Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001248-TA|BGIBMGA001248-PA|undefined
(698 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 92 7e-18
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 92 7e-18
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 91 1e-17
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 91 1e-17
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 91 1e-17
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 91 1e-17
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 91 1e-17
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 91 1e-17
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 91 1e-17
AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein pr... 91 2e-17
AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting p... 89 5e-17
AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting p... 89 5e-17
AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting p... 89 5e-17
AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting p... 89 5e-17
AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein. 89 5e-17
AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein. 89 5e-17
AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens ... 88 1e-16
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 87 2e-16
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 87 2e-16
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 87 2e-16
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 87 2e-16
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 87 2e-16
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 87 3e-16
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 86 5e-16
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 85 6e-16
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 85 6e-16
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 85 8e-16
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 85 8e-16
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 85 8e-16
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 85 8e-16
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 85 1e-15
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 85 1e-15
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 85 1e-15
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 84 1e-15
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 84 1e-15
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 84 2e-15
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 84 2e-15
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 84 2e-15
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 82 7e-15
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 81 1e-14
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 81 1e-14
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 81 1e-14
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 81 1e-14
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 81 1e-14
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 81 1e-14
AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein. 81 2e-14
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 81 2e-14
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 81 2e-14
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 81 2e-14
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 80 2e-14
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 80 2e-14
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 80 2e-14
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 80 2e-14
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 80 2e-14
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 80 2e-14
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 80 2e-14
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 80 3e-14
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 80 3e-14
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 80 3e-14
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 79 4e-14
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 79 4e-14
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 79 4e-14
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 79 4e-14
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 79 5e-14
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 79 7e-14
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 79 7e-14
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 79 7e-14
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 79 7e-14
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 79 7e-14
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 79 7e-14
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 79 7e-14
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 78 9e-14
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 78 9e-14
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 78 9e-14
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 78 9e-14
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 78 1e-13
AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FH... 78 1e-13
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 78 1e-13
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 77 2e-13
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 77 2e-13
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 77 2e-13
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 77 2e-13
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 77 2e-13
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 77 2e-13
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 77 3e-13
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 77 3e-13
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 77 3e-13
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 77 3e-13
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 77 3e-13
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 76 4e-13
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 76 4e-13
BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein. 76 4e-13
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 76 4e-13
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 76 4e-13
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 76 4e-13
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 76 4e-13
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 76 5e-13
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 76 5e-13
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 76 5e-13
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 76 5e-13
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 76 5e-13
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 76 5e-13
BC027860-1|AAH27860.1| 893|Homo sapiens filamin A interacting p... 75 6e-13
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 75 6e-13
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei... 75 6e-13
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 75 6e-13
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei... 75 6e-13
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 75 6e-13
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 75 6e-13
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 75 9e-13
U53445-1|AAA98972.1| 752|Homo sapiens DOC1 protein. 75 9e-13
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 75 9e-13
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 75 9e-13
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 75 9e-13
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 75 9e-13
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 75 9e-13
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 75 1e-12
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 75 1e-12
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 75 1e-12
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 75 1e-12
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 75 1e-12
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 75 1e-12
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 75 1e-12
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot... 74 1e-12
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 74 1e-12
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 74 1e-12
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 74 1e-12
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 74 1e-12
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 74 1e-12
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 74 1e-12
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 74 1e-12
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 74 1e-12
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 74 1e-12
AB067524-1|BAB67830.1| 704|Homo sapiens KIAA1937 protein protein. 74 1e-12
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 74 2e-12
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 74 2e-12
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 74 2e-12
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 74 2e-12
AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens ... 74 2e-12
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 73 3e-12
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 73 3e-12
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 73 3e-12
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 73 3e-12
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 73 3e-12
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 73 3e-12
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 73 3e-12
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 73 3e-12
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 73 3e-12
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 73 3e-12
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 73 3e-12
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 73 3e-12
AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein. 73 3e-12
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 73 5e-12
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 73 5e-12
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 73 5e-12
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 73 5e-12
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 73 5e-12
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 72 6e-12
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 72 6e-12
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 72 6e-12
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 72 6e-12
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 72 6e-12
AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluroni... 72 6e-12
L06148-1|AAA35921.1| 579|Homo sapiens golgin-165 protein. 72 8e-12
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 72 8e-12
D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein. 72 8e-12
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 72 8e-12
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 72 8e-12
BC048203-1|AAH48203.1| 663|Homo sapiens Unknown (protein for IM... 72 8e-12
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 72 8e-12
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 72 8e-12
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 72 8e-12
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 72 8e-12
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 72 8e-12
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 72 8e-12
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 72 8e-12
AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2... 72 8e-12
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 71 1e-11
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 71 1e-11
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 71 1e-11
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 71 1e-11
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 71 1e-11
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 71 2e-11
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein. 71 2e-11
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein. 71 2e-11
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 70 2e-11
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 70 2e-11
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 70 2e-11
BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosoph... 70 2e-11
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 70 2e-11
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 70 2e-11
AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosoph... 70 2e-11
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 70 2e-11
AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein. 70 2e-11
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 70 3e-11
Z98949-1|CAI17892.1| 2566|Homo sapiens protein ( Human DNA seque... 69 4e-11
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 69 4e-11
BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein. 69 4e-11
BC108282-1|AAI08283.1| 723|Homo sapiens Unknown (protein for IM... 69 4e-11
BC073850-1|AAH73850.1| 723|Homo sapiens RAD50 protein protein. 69 4e-11
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 69 4e-11
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 69 4e-11
AL080245-1|CAI16965.1| 2566|Homo sapiens protein ( Human DNA seq... 69 4e-11
AL079300-1|CAI17881.1| 2566|Homo sapiens protein ( Human DNA seq... 69 4e-11
AL022329-3|CAI17968.1| 2566|Homo sapiens protein ( Human DNA seq... 69 4e-11
AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens ... 69 4e-11
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 69 4e-11
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 69 4e-11
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 69 6e-11
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 69 6e-11
BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein. 69 6e-11
BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein. 69 6e-11
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 69 6e-11
BC012443-1|AAH12443.1| 717|Homo sapiens hook homolog 2 (Drosoph... 69 6e-11
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 69 6e-11
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 69 6e-11
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 69 6e-11
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 69 6e-11
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 69 6e-11
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 69 6e-11
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 69 7e-11
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 69 7e-11
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 69 7e-11
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 69 7e-11
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 69 7e-11
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 69 7e-11
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 69 7e-11
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 69 7e-11
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 69 7e-11
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 69 7e-11
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 69 7e-11
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 69 7e-11
AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens ... 69 7e-11
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 69 7e-11
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 68 1e-10
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 68 1e-10
BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein pr... 68 1e-10
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 68 1e-10
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 68 1e-10
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 68 1e-10
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ... 68 1e-10
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 68 1e-10
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 68 1e-10
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 68 1e-10
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 68 1e-10
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 68 1e-10
AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1 va... 68 1e-10
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 68 1e-10
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 68 1e-10
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 68 1e-10
BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated mot... 68 1e-10
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 68 1e-10
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 68 1e-10
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 68 1e-10
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 68 1e-10
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 68 1e-10
AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens ... 68 1e-10
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 68 1e-10
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 68 1e-10
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 68 1e-10
D67035-1|BAA22586.1| 973|Homo sapiens SCP-1 protein. 67 2e-10
DQ444714-1|ABE01857.1| 805|Homo sapiens cenexin 1 protein. 67 2e-10
DQ444713-1|ABE01856.1| 824|Homo sapiens cenexin 1 variant 1 pro... 67 2e-10
BC091500-1|AAH91500.1| 829|Homo sapiens ODF2 protein protein. 67 2e-10
BC010629-1|AAH10629.1| 763|Homo sapiens outer dense fiber of sp... 67 2e-10
AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1 p... 67 2e-10
AY366499-1|AAQ73195.1| 805|Homo sapiens outer dense fiber of sp... 67 2e-10
AL445287-6|CAH71069.1| 805|Homo sapiens outer dense fiber of sp... 67 2e-10
AL445287-5|CAH71068.1| 765|Homo sapiens outer dense fiber of sp... 67 2e-10
AL359091-23|CAI13506.1| 805|Homo sapiens outer dense fiber of s... 67 2e-10
AL359091-22|CAI13505.1| 765|Homo sapiens outer dense fiber of s... 67 2e-10
AJ310932-1|CAC70714.3| 2567|Homo sapiens myosin heavy chain prot... 67 2e-10
AJ310931-1|CAC70712.2| 2567|Homo sapiens myosin heavy chain prot... 67 2e-10
AB075376-1|BAC16363.1| 2567|Homo sapiens bk125H2.1 protein. 67 2e-10
AB042648-1|BAB55550.2| 2080|Homo sapiens bk125H2.1 protein. 67 2e-10
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 67 2e-10
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 67 2e-10
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 67 2e-10
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 67 2e-10
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 67 2e-10
BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein. 67 2e-10
BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein. 67 2e-10
BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein. 67 2e-10
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 67 2e-10
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 67 2e-10
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 67 2e-10
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 67 2e-10
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 66 3e-10
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 66 3e-10
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 66 3e-10
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 66 3e-10
BC011615-1|AAH11615.2| 739|Homo sapiens AZI1 protein protein. 66 3e-10
AY359522-1|AAQ57128.1| 657|Homo sapiens hypothetical protein DK... 66 3e-10
AL834265-1|CAD38940.1| 505|Homo sapiens hypothetical protein pr... 66 3e-10
AL445928-1|CAH72248.1| 657|Homo sapiens novel protein protein. 66 3e-10
AK092490-1|BAC03904.1| 280|Homo sapiens protein ( Homo sapiens ... 66 3e-10
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 66 3e-10
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 66 3e-10
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 66 3e-10
AB029041-1|BAA83070.1| 1165|Homo sapiens KIAA1118 protein protein. 66 3e-10
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 66 4e-10
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 66 4e-10
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 66 4e-10
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 66 4e-10
BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein. 66 4e-10
AY077700-1|AAL75811.1| 2568|Homo sapiens myosin-like protein pro... 66 4e-10
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 66 4e-10
BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil do... 66 5e-10
BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil do... 66 5e-10
BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance ... 66 5e-10
AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance ... 66 5e-10
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do... 66 5e-10
AF020043-1|AAC14893.1| 1217|Homo sapiens chromosome-associated p... 66 5e-10
AF011368-1|AAB84386.1| 761|Homo sapiens CEV14 protein. 66 5e-10
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein. 66 5e-10
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 65 7e-10
BC125087-1|AAI25088.1| 568|Homo sapiens CCDC41 protein protein. 65 7e-10
BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein. 65 7e-10
BC051733-1|AAH51733.1| 1026|Homo sapiens LUZP1 protein protein. 65 7e-10
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 65 7e-10
AL031428-1|CAI19705.1| 1026|Homo sapiens leucine zipper protein ... 65 7e-10
AK127744-1|BAC87110.1| 600|Homo sapiens protein ( Homo sapiens ... 65 7e-10
AK074153-1|BAB84979.1| 1046|Homo sapiens FLJ00226 protein protein. 65 7e-10
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 65 7e-10
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 65 9e-10
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 65 9e-10
BC101026-1|AAI01027.1| 490|Homo sapiens SASS6 protein protein. 65 9e-10
BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein. 65 9e-10
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 65 9e-10
BC008345-1|AAH08345.1| 963|Homo sapiens Unknown (protein for IM... 65 9e-10
AK000990-1|BAA91457.1| 535|Homo sapiens protein ( Homo sapiens ... 65 9e-10
AF273044-1|AAG34904.1| 761|Homo sapiens CTCL tumor antigen se2-... 65 9e-10
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 65 9e-10
D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein. 64 1e-09
BC129821-1|AAI29822.1| 315|Homo sapiens FLJ36144 protein protein. 64 1e-09
BC062603-1|AAH62603.1| 557|Homo sapiens Unknown (protein for IM... 64 1e-09
BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-co... 64 1e-09
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 64 1e-09
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 64 1e-09
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 64 1e-09
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 64 1e-09
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 64 1e-09
AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens ... 64 1e-09
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 64 1e-09
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 64 1e-09
BC068997-1|AAH68997.1| 541|Homo sapiens centrosomal protein 63k... 64 2e-09
BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3 (Drosoph... 64 2e-09
BC014050-1|AAH14050.1| 495|Homo sapiens centrosomal protein 63k... 64 2e-09
BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for IM... 64 2e-09
AY131226-1|AAN07912.1| 681|Homo sapiens medulloblastoma antigen... 64 2e-09
AL833308-1|CAD89924.1| 878|Homo sapiens hypothetical protein pr... 64 2e-09
AK056465-1|BAB71192.1| 703|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AK023738-1|BAB14662.1| 475|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AK023448-1|BAB14578.1| 541|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein. 64 2e-09
AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated microt... 64 2e-09
AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled co... 64 2e-09
AB007862-1|BAA23698.3| 3284|Homo sapiens KIAA0402 protein. 64 2e-09
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 64 2e-09
U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein. 63 3e-09
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 63 3e-09
AL137068-6|CAI12359.1| 346|Homo sapiens centrosomal protein 110... 63 3e-09
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 63 3e-09
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 63 4e-09
U51587-1|AAB81549.1| 767|Homo sapiens Golgi complex autoantigen... 63 4e-09
BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein. 63 4e-09
BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein. 63 4e-09
AK023677-1|BAB14636.1| 574|Homo sapiens protein ( Homo sapiens ... 63 4e-09
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 63 4e-09
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 63 4e-09
AF044924-1|AAC09299.1| 719|Homo sapiens hook2 protein protein. 63 4e-09
AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein. 63 4e-09
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 62 5e-09
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 62 5e-09
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 62 5e-09
BC032853-1|AAH32853.1| 767|Homo sapiens golgi autoantigen, golg... 62 5e-09
AL451125-2|CAI14346.1| 767|Homo sapiens golgi autoantigen, golg... 62 5e-09
AL354928-1|CAI39632.1| 767|Homo sapiens golgi autoantigen, golg... 62 5e-09
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 62 5e-09
AF432211-1|AAL99918.1| 460|Homo sapiens CLL-associated antigen ... 62 5e-09
BC133019-1|AAI33020.1| 1427|Homo sapiens LOC650001 protein protein. 62 6e-09
AL138742-1|CAI22698.1| 1325|Homo sapiens KIAA1009 protein. 62 6e-09
AK125995-1|BAC86384.1| 842|Homo sapiens protein ( Homo sapiens ... 62 6e-09
AB023226-1|BAA76853.2| 1345|Homo sapiens KIAA1009 protein protein. 62 6e-09
AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens ... 62 9e-09
AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2 ... 62 9e-09
BC128578-1|AAI28579.1| 751|Homo sapiens RRBP1 protein protein. 61 1e-08
BC128577-1|AAI28578.1| 934|Homo sapiens RRBP1 protein protein. 61 1e-08
BC029425-1|AAH29425.1| 272|Homo sapiens Unknown (protein for IM... 61 1e-08
AF006751-1|AAC25977.1| 977|Homo sapiens ES/130 protein. 61 1e-08
AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein. 61 1e-08
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 61 1e-08
AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 2... 61 1e-08
AK097021-1|BAC04928.1| 512|Homo sapiens protein ( Homo sapiens ... 61 1e-08
AB033055-1|BAA86543.1| 696|Homo sapiens KIAA1229 protein protein. 61 1e-08
AB011137-1|BAA25491.2| 641|Homo sapiens KIAA0565 protein protein. 61 1e-08
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 60 2e-08
BC104044-1|AAI04045.1| 830|Homo sapiens kinesin family member 7... 60 2e-08
BC092419-1|AAH92419.1| 701|Homo sapiens hypothetical LOC550631 ... 60 2e-08
AL132765-6|CAC10587.1| 977|Homo sapiens ribosome binding protei... 60 2e-08
AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protei... 60 2e-08
BC021134-1|AAH21134.1| 903|Homo sapiens centrobin, centrosomal ... 60 3e-08
BC014055-1|AAH14055.3| 805|Homo sapiens CNTROB protein protein. 60 3e-08
BC003177-1|AAH03177.1| 691|Homo sapiens calcium binding and coi... 60 3e-08
AY563137-1|AAT68474.1| 691|Homo sapiens calphoglin protein. 60 3e-08
AY358397-1|AAQ88763.1| 691|Homo sapiens EESP2436 protein. 60 3e-08
AY160227-1|AAO22136.1| 925|Homo sapiens centrobin beta protein. 60 3e-08
AY160226-1|AAO22135.1| 903|Homo sapiens centrobin alpha protein. 60 3e-08
AL136382-2|CAI23514.1| 636|Homo sapiens novel protein protein. 60 3e-08
AK129960-1|BAC85259.1| 488|Homo sapiens protein ( Homo sapiens ... 60 3e-08
AK027881-1|BAB55428.1| 690|Homo sapiens protein ( Homo sapiens ... 60 3e-08
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 60 3e-08
AB040969-1|BAA96060.1| 645|Homo sapiens KIAA1536 protein protein. 60 3e-08
AB033102-1|BAA86590.1| 1068|Homo sapiens KIAA1276 protein protein. 60 3e-08
BX530088-1|CAI95784.1| 810|Homo sapiens GRIP1 associated protei... 60 3e-08
BC050548-1|AAH50548.1| 1127|Homo sapiens KIF4A protein protein. 60 3e-08
BC044814-1|AAH44814.1| 374|Homo sapiens coiled-coil domain cont... 60 3e-08
AL357752-3|CAI41487.1| 1232|Homo sapiens kinesin family member 4... 60 3e-08
AL139398-5|CAI41024.1| 1232|Homo sapiens kinesin family member 4... 60 3e-08
AK095478-1|BAC04556.1| 374|Homo sapiens protein ( Homo sapiens ... 60 3e-08
AB046821-1|BAB13427.1| 690|Homo sapiens KIAA1601 protein protein. 60 3e-08
Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of... 59 5e-08
X14298-1|CAA32479.1| 3685|Homo sapiens protein ( Human mRNA for ... 59 5e-08
S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein. 59 5e-08
D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein. 59 5e-08
DQ679757-1|ABG74698.1| 1215|Homo sapiens intersectin 1 short for... 59 5e-08
DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short for... 59 5e-08
DQ679755-1|ABG74696.1| 1149|Homo sapiens intersectin 1 short for... 59 5e-08
DQ679754-1|ABG74695.1| 1144|Homo sapiens intersectin 1 short for... 59 5e-08
DQ386455-1|ABD72328.1| 1020|Homo sapiens intersectin 1 short for... 59 5e-08
DQ340865-1|ABC69037.1| 1076|Homo sapiens intersectin 1 short for... 59 5e-08
DQ120629-1|ABB92415.1| 1185|Homo sapiens KIF4B protein. 59 5e-08
BX538175-1|CAD98050.1| 627|Homo sapiens hypothetical protein pr... 59 5e-08
BC117560-1|AAI17561.1| 1144|Homo sapiens ITSN1 protein protein. 59 5e-08
BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 doma... 59 5e-08
BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein. 59 5e-08
BC115701-1|AAI15702.1| 828|Homo sapiens SLMAP protein protein. 59 5e-08
BC112273-1|AAI12274.1| 830|Homo sapiens kinesin family member 7... 59 5e-08
BC112271-1|AAI12272.1| 830|Homo sapiens kinesin family member 7... 59 5e-08
BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural mainten... 59 5e-08
BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein. 59 5e-08
AY358384-1|AAQ88750.1| 830|Homo sapiens EQYK340 protein. 59 5e-08
AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance ... 59 5e-08
AF345347-1|AAL06396.2| 1135|Homo sapiens mitotic spindle-associa... 59 5e-08
AF304450-1|AAG41949.1| 359|Homo sapiens sarcolemmal associated ... 59 5e-08
AF282265-1|AAF87584.1| 919|Homo sapiens inner centromere protei... 59 5e-08
AF114488-1|AAD29953.1| 1220|Homo sapiens intersectin short isofo... 59 5e-08
AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isofor... 59 5e-08
AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350 ... 59 5e-08
AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form p... 59 5e-08
AF064243-1|AAC78610.1| 1220|Homo sapiens intersectin short form ... 59 5e-08
AB023222-1|BAA76849.1| 1055|Homo sapiens KIAA1005 protein protein. 59 5e-08
AB018346-1|BAA34523.1| 1708|Homo sapiens KIAA0803 protein protein. 59 5e-08
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 59 6e-08
CR533567-1|CAG38598.1| 691|Homo sapiens KIAA1536 protein. 59 6e-08
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 59 6e-08
BC003664-1|AAH03664.1| 787|Homo sapiens Unknown (protein for IM... 59 6e-08
AF266285-1|AAF72535.1| 693|Homo sapiens golgin-like protein pro... 59 6e-08
AB208797-1|BAD92034.1| 1235|Homo sapiens Chromosome-associated k... 59 6e-08
M18533-1|AAA53189.1| 3685|Homo sapiens dystrophin protein. 58 8e-08
AL451144-4|CAI39566.1| 3685|Homo sapiens dystrophin (muscular dy... 58 8e-08
AL139278-1|CAI42991.1| 3685|Homo sapiens dystrophin (muscular dy... 58 8e-08
AL109609-3|CAI42950.1| 3685|Homo sapiens dystrophin (muscular dy... 58 8e-08
AL096699-2|CAI42225.1| 3685|Homo sapiens dystrophin (muscular dy... 58 8e-08
AL031643-3|CAI43058.1| 3685|Homo sapiens dystrophin (muscular dy... 58 8e-08
AL031542-2|CAI42229.1| 3685|Homo sapiens dystrophin (muscular dy... 58 8e-08
AF331638-1|AAL56068.2| 903|Homo sapiens PP1221 protein. 58 8e-08
AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H1... 58 8e-08
U72849-1|AAD00186.1| 2033|Homo sapiens envoplakin protein. 58 1e-07
U53786-1|AAC64662.1| 2033|Homo sapiens envoplakin protein. 58 1e-07
D86326-1|BAA25300.1| 962|Homo sapiens p115 protein. 58 1e-07
BC126105-1|AAI26106.1| 2033|Homo sapiens envoplakin protein. 58 1e-07
BC126103-1|AAI26104.1| 2033|Homo sapiens envoplakin protein. 58 1e-07
BC032654-1|AAH32654.1| 961|Homo sapiens vesicle docking protein... 58 1e-07
AL137265-1|CAB70664.1| 992|Homo sapiens hypothetical protein pr... 58 1e-07
AB028975-1|BAA83004.2| 1456|Homo sapiens KIAA1052 protein protein. 58 1e-07
BC132717-1|AAI32718.1| 1132|Homo sapiens phosphodiesterase 4D in... 58 1e-07
BC131515-1|AAI31516.1| 632|Homo sapiens GOLGA6 protein protein. 58 1e-07
BC078660-1|AAH78660.1| 1132|Homo sapiens phosphodiesterase 4D in... 58 1e-07
BC038515-1|AAH38515.1| 796|Homo sapiens CCDC110 protein protein. 58 1e-07
BC028419-1|AAH28419.1| 833|Homo sapiens coiled-coil domain cont... 58 1e-07
AL832010-1|CAD89917.1| 973|Homo sapiens hypothetical protein pr... 58 1e-07
AL590452-2|CAH72522.1| 1132|Homo sapiens phosphodiesterase 4D in... 58 1e-07
AL138796-2|CAI22822.1| 1132|Homo sapiens phosphodiesterase 4D in... 58 1e-07
AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein pr... 58 1e-07
AF272390-1|AAF78783.1| 1742|Homo sapiens myosin 5c protein. 58 1e-07
AB080722-1|BAC81776.1| 833|Homo sapiens hypothetical protein pr... 58 1e-07
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 58 1e-07
AB007946-1|BAA32322.2| 1148|Homo sapiens KIAA0477 protein protein. 58 1e-07
X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (... 57 2e-07
U06698-1|AAA20231.1| 1032|Homo sapiens neuronal kinesin heavy ch... 57 2e-07
M83216-1|AAA58419.1| 793|Homo sapiens caldesmon protein. 57 2e-07
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 57 2e-07
M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac m... 57 2e-07
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 57 2e-07
BC019283-1|AAH19283.1| 469|Homo sapiens TRAF interacting protei... 57 2e-07
BC000310-1|AAH00310.1| 469|Homo sapiens TRAF interacting protei... 57 2e-07
Y15164-1|CAA75436.1| 1012|Homo sapiens Cxorf5 (71-7A) protein pr... 57 2e-07
X65873-1|CAA46703.1| 963|Homo sapiens kinesin heavy chain protein. 57 2e-07
BC126281-1|AAI26282.1| 963|Homo sapiens kinesin family member 5... 57 2e-07
>AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 91.9 bits (218), Expect = 7e-18
Identities = 113/556 (20%), Positives = 241/556 (43%), Gaps = 34/556 (6%)
Query: 115 WTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSR 174
W Q+ + RD + E + E + ++ + L+ NQ++ + +
Sbjct: 1253 WKTQQTRDVLRDQV-QKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKS----KWEGK 1307
Query: 175 YNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVET 234
N EL L E + + A ER L A E L +V L+ V
Sbjct: 1308 QNSLESELM-ELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVE 1366
Query: 235 RNVMIDEIRELRSESENTK-ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKM 293
L + + AL+ E++ ER A++E+ +Q + + +A +
Sbjct: 1367 ARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALL 1426
Query: 294 DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARA---RKLRESLKTGEVTTSQLIQQR 350
+ L E E + +L G ++ LE Q ++ LE + +K + + + +L + R
Sbjct: 1427 TQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCR 1486
Query: 351 DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL 410
L+ + +++ +KLTVQ + I++LE+D + + L+ Q +++ ++ E ++
Sbjct: 1487 SVLEHLPMAVQEREQKLTVQREQ-IRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQV 1545
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
QD + + L+ +ELE++ E + L EL+ +ET RV +T E+
Sbjct: 1546 QDLKKQLVTLECLALELEENHHK----MECQQKLIKELEGQRETQRVALTHLTLDLEERS 1601
Query: 471 SENKIGIQQKLAAELLNKEEIIGK-MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRT 529
E + Q +L + ++ + +Q + +E+ + E+ Q E +DL+ ++
Sbjct: 1602 QE--LQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQE 1659
Query: 530 IANCQESPNGISYQDLQQ-EIM--DLKMKLLDVVHRNEELS---EILAKKDQELEQQDKN 583
+ +E + Q +Q +I+ DL+ L + R EL+ +++ ++ +E + K
Sbjct: 1660 LMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKA 1719
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
RG +K+ +L++KE +E+ Q+ + + D++ +Q+ ++ E
Sbjct: 1720 QRGSLEHMKL------ILRDKE----KEVECQQEHIHELQELKDQLEQQLQGLHRKVGET 1769
Query: 644 FATLENKQQQIHRLEK 659
L ++Q+I L++
Sbjct: 1770 SLLLSQREQEIVVLQQ 1785
Score = 81.8 bits (193), Expect = 7e-15
Identities = 104/459 (22%), Positives = 214/459 (46%), Gaps = 53/459 (11%)
Query: 219 EALVREVAKLRQDV----ETRNVMIDEIRELRSESENTKA--------LEEMRHELDEER 266
EA+ + KL QD+ +TR+V+ D++++L +T+A L++++ +L + +
Sbjct: 1239 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQ 1298
Query: 267 TAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKML----EDQSRQKE 322
K + K + ES+L + +A + +LR AE G ++L E+ + Q E
Sbjct: 1299 EEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVE 1358
Query: 323 ----VQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKS 373
+EARA+ L E L+T + +L + + E + Q+ +L V
Sbjct: 1359 HLQAAVVEARAQASAAGILEEDLRTAR-SALKLKNEEVESERERAQALQEQGELKVAQGK 1417
Query: 374 AIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN 433
A+Q+ L QT +E+ E + +I+ E+ + E+Q + A+E L ++L+K
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEK-QREMQ--KAALELLS---LDLKKRNQE 1471
Query: 434 PDLPTE--REID--------LWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
DL E +E++ L +Q ++ L V +++ ++++E++ + Q L
Sbjct: 1472 VDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLL-- 1529
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC--QESPNGIS 541
EL K+++I + Q ++L K + E ++ E+ ++ + I Q ++
Sbjct: 1530 ELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVA 1589
Query: 542 YQDLQQEIMDLKMKL---LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI-KIREEL 597
L ++ + +L +H E S +LA++ QE +Q+ K+ R Q + + +E L
Sbjct: 1590 LTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHL 1649
Query: 598 INVLKNKETE---QSRELAALQQDLEHRMRIVDEVNKQI 633
L+ ++ E Q + L+ + +I++E +QI
Sbjct: 1650 TQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQI 1688
Score = 73.3 bits (172), Expect = 3e-12
Identities = 87/423 (20%), Positives = 189/423 (44%), Gaps = 39/423 (9%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
R+ V AL R + + + N + E+ +LR+ + AL E LD K+
Sbjct: 560 RQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEAL-ALD-----KV 613
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
+ ++L E + + +R+ ++ + + + + +K LEA+ +
Sbjct: 614 GLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAE----AEKRREALWEKNTHLEAQLQ 669
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K E+ + + ++++ +Q ++ E + Q E T Q + Q+ + + RA+Q
Sbjct: 670 KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQ 729
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQA-----KIIE---LEKSKPNPDLPTEREI 442
E+ + + + L+ R + +D ++ E+LQ +++E E + N + +
Sbjct: 730 EKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKG- 788
Query: 443 DLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK-LAAELLNKEEIIGKMQIQTRE 501
L ++Q + V + EV K E ++E Q++ AA L + E GK ++ ++
Sbjct: 789 QLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQK 848
Query: 502 LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVH 561
++N+ + E++ ++ H + +A ES L++E M+L+M+L +
Sbjct: 849 AAHEKEVNQLR----EKWEKERSWHQQELAKALES--------LEREKMELEMRLKE--- 893
Query: 562 RNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLKNKETE---QSRELAALQQ 617
+ E+ I A++++E Q + + Q K R L+ L + E S++L L+Q
Sbjct: 894 QQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQ 953
Query: 618 DLE 620
D++
Sbjct: 954 DMK 956
Score = 61.3 bits (142), Expect = 1e-08
Identities = 75/410 (18%), Positives = 178/410 (43%), Gaps = 14/410 (3%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
+E+ L+Q+ + + ++E + ALE+ L E KE+ E +
Sbjct: 1817 QELEALQQEQQQAQGQEERVKEKADALQG--ALEQAHMTLKERHGELQDHKEQARRLEEE 1874
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVT 342
L RV +++ L + A + L+ Q ++ + E R L++S +
Sbjct: 1875 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAV 1934
Query: 343 TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL 402
+ Q+ ++L+AE + Q E ++ + L+E L + ALQ + + + EL
Sbjct: 1935 LKERDQELEALRAESQSSRHQEEAA----RARAEALQEALGKAHAALQGKEQHLLEQAEL 1990
Query: 403 KERTETELQDSRNAIEELQAKIIELEKS-KPNPDLPTEREIDLWAELQATKETLRVTEDE 461
E + +++ QA +LE++ + ++++ ++Q ++ L DE
Sbjct: 1991 SRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQAL-AQRDE 2049
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIG--KMQIQTRELIKNIKLNEQKVIQYEQY 519
++E+E + + Q++ ++ +++ +G + + + R L ++++ + + Q EQ
Sbjct: 2050 ELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQE 2109
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
+ +L+ + N + P+ S++ E LK+ L+ + E A + E +
Sbjct: 2110 ILELR-ETQQRNNLEALPH--SHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEARE 2166
Query: 580 QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEV 629
+ + Q + + + +V +E + + L++D E + R+ DE+
Sbjct: 2167 IEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSE-QQRLQDEL 2215
Score = 60.9 bits (141), Expect = 1e-08
Identities = 106/478 (22%), Positives = 203/478 (42%), Gaps = 50/478 (10%)
Query: 219 EALVREVAKLRQDVETRN--VMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEK- 275
E L R+ L QD+E R+ +M+ + R E + T+ + + +L++ KL+++E+
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQ---IKLSLRERG 1696
Query: 276 -LTTTESQLRQTRNRVAK------------MDKQLREAEASITSLTGTVKMLEDQSRQKE 322
TT+ QL Q R K M LR+ E + + L++ Q E
Sbjct: 1697 RELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLE 1756
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDL 382
QL+ RK+ E TS L+ QR+ E++ +QQ+++ Q + Q L+ L
Sbjct: 1757 QQLQGLHRKVGE--------TSLLLSQREQ---EIVVLQQQLQEAREQGELKEQSLQSQL 1805
Query: 383 KQTKRAL---QEQCEITKREIELKERTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPT 438
+ +RAL ++ E ++E + + E +++ +A++ L+ + L++
Sbjct: 1806 DEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHK 1865
Query: 439 EREIDLWAELQATKETLRVTEDEVTTCKREKESENK--IGIQQKLAAELLNKEEIIGKMQ 496
E+ L EL ++ E+ + + E + K + +QQ+ A + E +Q
Sbjct: 1866 EQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQ 1925
Query: 497 ---IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLK 553
+Q + ++K + + Q R + R A + G ++ LQ + +
Sbjct: 1926 DSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGK----E 1981
Query: 554 MKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI--NVLKNKETEQSRE 611
LL+ + L A L+ +SR ++I+E I L+ +E Q +
Sbjct: 1982 QHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQ 2041
Query: 612 LAALQQD--LEHRMRIVDEVNKQIAAKADE--IQE-LFATLENKQQQIHRLEKIVLAL 664
A Q+D L H+ + K +A + E IQE E ++++I L + V L
Sbjct: 2042 QALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVREL 2099
Score = 58.0 bits (134), Expect = 1e-07
Identities = 120/570 (21%), Positives = 249/570 (43%), Gaps = 52/570 (9%)
Query: 118 QEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYND 177
+E A+ +RD +A+ E++ LL + M ++ ++ K+ L V QD + + + +
Sbjct: 981 KEAARQHRDDLAALQEESS-SLLQDKMDLQKQVEDLKSQL-VAQDDSQRLVEQEVQEKLR 1038
Query: 178 QGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR--EVAKLRQDVETR 235
+ E +EL + E A T++ + K E+R L+ +R E++ LRQD++
Sbjct: 1039 ETQEYNRIQKEL--EREKASLTLSLMEK----EQRLLVLQEADSIRQQELSALRQDMQEA 1092
Query: 236 NVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQT----RNRV 290
E +EL ++ E + ++E + + L E TE QLR + +
Sbjct: 1093 Q---GEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKA 1149
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
A++ +LR E+ + +L + Q + QL + L+++L + + +L
Sbjct: 1150 AQLQLRLRSTESQLEALAA--EQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGG 1207
Query: 351 DSLQAEV-LECKQQ-----------IEKLTVQH-KSAIQQLEEDL---KQTKRALQEQCE 394
DS + LE Q + L+ + SA+ +L +DL +QT+ L++Q
Sbjct: 1208 DSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQ-- 1265
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET 454
+ K E L + TE E +++LQ ++ + ++ K + ++ L +EL ET
Sbjct: 1266 VQKLEERLTD-TEAEKSQVHTELQDLQRQLSQNQEEKSKWE---GKQNSLESELMELHET 1321
Query: 455 LRVTEDEVTTCKREK-ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ + + + ++ E++ + + Q L + E + ++ R + E+ +
Sbjct: 1322 MASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDL 1381
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQD----LQQEIMDLKMKLL-DVVHRNEELSE 568
L+ N + + +E + Q Q + + + LL + EE E
Sbjct: 1382 RTARSA---LKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVE 1438
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L + QELE+Q + + ++ + + N + + EQ +EL + LEH V E
Sbjct: 1439 TLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQE 1498
Query: 629 VNKQIAAKADEIQELFATLENKQQQI-HRL 657
+++ + ++I+EL E ++ + H+L
Sbjct: 1499 REQKLTVQREQIRELEKDRETQRNVLEHQL 1528
Score = 55.2 bits (127), Expect = 7e-07
Identities = 107/512 (20%), Positives = 231/512 (45%), Gaps = 49/512 (9%)
Query: 168 ILEHLSRYNDQGFELCGALRE----LKTQAEDAVNTVTDLSKRACHERRTLIAV----GE 219
+L + N+ ++ ALRE L+T + + LS+ A E+ +L V +
Sbjct: 291 LLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQ 350
Query: 220 ALVREVAKLRQDVETRNVM-IDE-IRELRSESENTKALEEMRHELDEERTAKLAIKEKLT 277
+V E + Q N + +D I + KAL +R L R A ++++L
Sbjct: 351 VMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLA 410
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
+ + + + + +++ + + LTG L Q+ + ++++ +++ RE L+
Sbjct: 411 GCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE-RELLQ 469
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
+L QQ + L+ E ++ +L +Q SA Q EE ++ A++E+ + +
Sbjct: 470 KAR---EELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQE 526
Query: 398 REIELKERTE---TELQDSRNAIEE--LQAKIIELEKSKPNPDLP-TEREIDLWAELQAT 451
+ L+ + +EL R A+E L+ +++ E+++ L E+ I AEL ++
Sbjct: 527 MLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSI---AELSSS 583
Query: 452 KETLR--VTEDEVTTCKREKESE----NKIGIQQKLAAELLNKEEIIGKMQI--QTRELI 503
+ TL+ V + K +E +K+G+ Q+L + + +M+ Q R +
Sbjct: 584 ENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNAL 643
Query: 504 KNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS--YQDLQQEIMDLKMKLLDVVH 561
+ + L E + + + ++ + + +E+ + +D+Q+E +++ KL + H
Sbjct: 644 Q-VDLAEAEKRREALWEKNTHLEAQ-LQKAEEAGAELQADLRDIQEEKEEIQKKLSESRH 701
Query: 562 RNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEH 621
+ E + L + QE ++Q++ AR ++ +E L+ RE AAL+ L+
Sbjct: 702 QQEAATTQLEQLHQEAKRQEEVL---ARAVQEKEALV-----------REKAALEVRLQA 747
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQ 653
R ++ +Q+ + + L ++L QQQ
Sbjct: 748 VERDRQDLAEQLQGLSSAKELLESSLFEAQQQ 779
Score = 54.8 bits (126), Expect = 1e-06
Identities = 105/535 (19%), Positives = 221/535 (41%), Gaps = 38/535 (7%)
Query: 133 PENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQ 192
P L LL +T +E L Q ++ GD+ + + D+ EL L + + Q
Sbjct: 243 PAQLLLLLAKTQELEKEAHERSQELI--QLKSQGDLEK--AELQDRVTELSALLTQSQKQ 298
Query: 193 AEDAVNTVTDLSKRA--CHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESE 250
ED + L + T + EA + A+ + + + V+ D + + E +
Sbjct: 299 NEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQ-EEKLSLQQVIKDITQVMVEEGD 357
Query: 251 NTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGT 310
N + HE E + + + + L R+ + + + +++ +
Sbjct: 358 NIA--QGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEA 415
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
V +L+ Q Q E + +A ++L++ TGE RD+L + ++ + +++ L+ +
Sbjct: 416 VNLLQQQHDQWEEEGKALRQRLQKL--TGE---------RDTLAGQTVDLQGEVDSLS-K 463
Query: 371 HKSAIQQLEEDLKQTKRAL-QEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEK 429
+ +Q+ E+L+Q L QE + + +EL+ + ++ EEL + E E+
Sbjct: 464 ERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERER 523
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREK-ESENKIGIQQKLAAELLNK 488
+ ++ + +EL +E L + E ++E+ E + ++ AEL +
Sbjct: 524 LQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSS 583
Query: 489 EEIIGKMQIQTR-ELIKNIKLNEQKVIQ---YEQYVRDLQAHNRTIANCQESPNGISYQD 544
E + R +K LNE + Q + L+ N+++ + E+
Sbjct: 584 ENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEA-------- 635
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKN 603
+Q L++ L + R E L E + +L++ ++ + QA + I+EE + K
Sbjct: 636 AEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKK 695
Query: 604 -KETEQSRELAALQ-QDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
E+ +E A Q + L + +EV + + + + A LE + Q + R
Sbjct: 696 LSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVER 750
Score = 53.6 bits (123), Expect = 2e-06
Identities = 103/507 (20%), Positives = 213/507 (42%), Gaps = 62/507 (12%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVE---TRNVMIDEIR-- 243
L+TQ ++A + + +++ + L +L+++ L++ VE ++ V D+ +
Sbjct: 969 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL 1028
Query: 244 ---ELRSESENTKALEEMRHELDEER---TAKLAIKEKLTTTESQLRQTRNR-VAKMDKQ 296
E++ + T+ ++ EL+ E+ T L KE+ + R + ++ + +
Sbjct: 1029 VEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQD 1088
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL-----IQQRD 351
++EA+ L+ +++L + ++KE A+ +L E L+ +T QL Q+
Sbjct: 1089 MQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAK 1148
Query: 352 S--LQAEVLECKQQIEKLTVQHKSAIQ-QLEEDLKQTKRALQEQC-EITKREIELKERTE 407
+ LQ + + Q+E L + + Q Q + L ALQ+ + + EL +
Sbjct: 1149 AAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGD 1208
Query: 408 TE-----LQDSRNAIEEL--QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
+ L+ +N L + ++ ++ + DLW + Q T++ LR D
Sbjct: 1209 SAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLW-KTQQTRDVLR---D 1264
Query: 461 EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYV 520
+V QKL L + E ++ + ++L + + N+++ ++E
Sbjct: 1265 QV----------------QKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQ 1308
Query: 521 RDLQAHNRTIANCQES-PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
L++ + S + + +LQ+ + +LL N L + + L+
Sbjct: 1309 NSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKEN------LTAQVEHLQA 1362
Query: 580 QDKNSRGQARVIKIREELINV------LKNKETEQSRELA-ALQQDLEHRMRIVDEVNKQ 632
+R QA I EE + LKN+E E RE A ALQ+ E ++ + +
Sbjct: 1363 AVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQEN 1422
Query: 633 IAAKADEIQELFATLENKQQQIHRLEK 659
+A + E +E + QI LEK
Sbjct: 1423 LALLTQTLAEREEEVETLRGQIQELEK 1449
Score = 47.2 bits (107), Expect = 2e-04
Identities = 100/489 (20%), Positives = 197/489 (40%), Gaps = 44/489 (8%)
Query: 177 DQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN 236
DQ E A + E+A + + A + + E + E A+L + +E
Sbjct: 1939 DQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEAST 1998
Query: 237 VMIDEIRELRSESENTKALEE-MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
+ L + +++ LEE +R + E + L +E + + L Q + +
Sbjct: 1999 ATLQA--SLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQE 2056
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ----LIQQRD 351
+ + E S+ + E Q+ +E + E R L +S++ ++T +Q +++ R+
Sbjct: 2057 REQLLEKSLAQRVQENMIQEKQNLGQERE-EEEIRGLHQSVRELQLTLAQKEQEILELRE 2115
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQ--QLEEDLKQTKRALQEQCEITK-REIELKERTET 408
+ Q LE K + + +++ LE L++ LQ T+ REIE +E+ +
Sbjct: 2116 TQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQD 2175
Query: 409 ---ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE--DEVT 463
L ++ ++ LQ + L+ S D +R D EL+ T+ L
Sbjct: 2176 LALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQD---ELELTRRALEKERLHSPGA 2232
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
T E S + G+Q + + + G + R+ ++++ +Q V + E L
Sbjct: 2233 TSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHL---QQAVARLEIDRSRL 2289
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNE-ELSEILAKKDQELEQQ-D 581
Q HN + + E +++E LK + + E+S+ A + + +
Sbjct: 2290 QRHNVQLRSTLEQ--------VERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQ 2341
Query: 582 KNSRG------QARVIKIREELINVLKNKE------TEQSRELAALQQDLEHRMRIVDEV 629
KNS Q V+ ++ +L K K+ + SRELA L L H + V +
Sbjct: 2342 KNSDAKCVAELQKEVVLLQAQLTLERKQKQDYITRSAQTSRELAGLHHSLSHSLLAVAQA 2401
Query: 630 NKQIAAKAD 638
+ +A+
Sbjct: 2402 PEATVLEAE 2410
Score = 42.3 bits (95), Expect = 0.006
Identities = 73/379 (19%), Positives = 159/379 (41%), Gaps = 31/379 (8%)
Query: 178 QGFELCGALRELKTQAEDAVNTVTDLSKRACHER-RTLIAVGEALVREVAKLRQDVETRN 236
QG L E N+V +++K + +T+ E + EV L+ +++T
Sbjct: 760 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819
Query: 237 VMIDEIREL------RSESENTKALEEMR--HELDEERTAKLAIKEKLTTTES---QLRQ 285
++ R+ ++E E ALE+ + HE + + + KE+ + L
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALES 879
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+++ +L+E + + ++ + Q+ Q++ K R SL + T +
Sbjct: 880 LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQK 939
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAI-----QQLEEDLKQTKRALQEQCEITKREI 400
+ S Q E L +++KL Q + I Q+ + +LK+ R Q + ++ +
Sbjct: 940 ELADA-SQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAAR--QHRDDLAALQE 996
Query: 401 ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
E + ++ D + +E+L+++++ + S+ + + ++ E ++ L +
Sbjct: 997 ESSSLLQDKM-DLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKA 1055
Query: 461 EVTTCKREKE------SENKIGIQQKLAAELLNKEEIIG---KMQIQTRELIKNIKLNEQ 511
+T EKE E QQ+L+A + +E G ++ Q L + +K E
Sbjct: 1056 SLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEA 1115
Query: 512 KVIQYE-QYVRDLQAHNRT 529
+ E Q + +L+A + T
Sbjct: 1116 DFLAQEAQLLEELEASHIT 1134
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associated
protein 1 protein.
Length = 2442
Score = 91.9 bits (218), Expect = 7e-18
Identities = 113/556 (20%), Positives = 241/556 (43%), Gaps = 34/556 (6%)
Query: 115 WTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSR 174
W Q+ + RD + E + E + ++ + L+ NQ++ + +
Sbjct: 1253 WKTQQTRDVLRDQV-QKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKS----KWEGK 1307
Query: 175 YNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVET 234
N EL L E + + A ER L A E L +V L+ V
Sbjct: 1308 QNSLESELM-ELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVE 1366
Query: 235 RNVMIDEIRELRSESENTK-ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKM 293
L + + AL+ E++ ER A++E+ +Q + + +A +
Sbjct: 1367 ARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALL 1426
Query: 294 DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARA---RKLRESLKTGEVTTSQLIQQR 350
+ L E E + +L G ++ LE Q ++ LE + +K + + + +L + R
Sbjct: 1427 TQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCR 1486
Query: 351 DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL 410
L+ + +++ +KLTVQ + I++LE+D + + L+ Q +++ ++ E ++
Sbjct: 1487 SVLEHLPMAVQEREQKLTVQREQ-IRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQV 1545
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
QD + + L+ +ELE++ E + L EL+ +ET RV +T E+
Sbjct: 1546 QDLKKQLVTLECLALELEENHHK----MECQQKLIKELEGQRETQRVALTHLTLDLEERS 1601
Query: 471 SENKIGIQQKLAAELLNKEEIIGK-MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRT 529
E + Q +L + ++ + +Q + +E+ + E+ Q E +DL+ ++
Sbjct: 1602 QE--LQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQE 1659
Query: 530 IANCQESPNGISYQDLQQ-EIM--DLKMKLLDVVHRNEELS---EILAKKDQELEQQDKN 583
+ +E + Q +Q +I+ DL+ L + R EL+ +++ ++ +E + K
Sbjct: 1660 LMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKA 1719
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
RG +K+ +L++KE +E+ Q+ + + D++ +Q+ ++ E
Sbjct: 1720 QRGSLEHMKL------ILRDKE----KEVECQQEHIHELQELKDQLEQQLQGLHRKVGET 1769
Query: 644 FATLENKQQQIHRLEK 659
L ++Q+I L++
Sbjct: 1770 SLLLSQREQEIVVLQQ 1785
Score = 81.8 bits (193), Expect = 7e-15
Identities = 104/459 (22%), Positives = 214/459 (46%), Gaps = 53/459 (11%)
Query: 219 EALVREVAKLRQDV----ETRNVMIDEIRELRSESENTKA--------LEEMRHELDEER 266
EA+ + KL QD+ +TR+V+ D++++L +T+A L++++ +L + +
Sbjct: 1239 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQ 1298
Query: 267 TAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKML----EDQSRQKE 322
K + K + ES+L + +A + +LR AE G ++L E+ + Q E
Sbjct: 1299 EEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVE 1358
Query: 323 ----VQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKS 373
+EARA+ L E L+T + +L + + E + Q+ +L V
Sbjct: 1359 HLQAAVVEARAQASAAGILEEDLRTAR-SALKLKNEEVESERERAQALQEQGELKVAQGK 1417
Query: 374 AIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN 433
A+Q+ L QT +E+ E + +I+ E+ + E+Q + A+E L ++L+K
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEK-QREMQ--KAALELLS---LDLKKRNQE 1471
Query: 434 PDLPTE--REID--------LWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
DL E +E++ L +Q ++ L V +++ ++++E++ + Q L
Sbjct: 1472 VDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLL-- 1529
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC--QESPNGIS 541
EL K+++I + Q ++L K + E ++ E+ ++ + I Q ++
Sbjct: 1530 ELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVA 1589
Query: 542 YQDLQQEIMDLKMKL---LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI-KIREEL 597
L ++ + +L +H E S +LA++ QE +Q+ K+ R Q + + +E L
Sbjct: 1590 LTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHL 1649
Query: 598 INVLKNKETE---QSRELAALQQDLEHRMRIVDEVNKQI 633
L+ ++ E Q + L+ + +I++E +QI
Sbjct: 1650 TQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQI 1688
Score = 73.3 bits (172), Expect = 3e-12
Identities = 87/423 (20%), Positives = 189/423 (44%), Gaps = 39/423 (9%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
R+ V AL R + + + N + E+ +LR+ + AL E LD K+
Sbjct: 560 RQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEAL-ALD-----KV 613
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
+ ++L E + + +R+ ++ + + + + +K LEA+ +
Sbjct: 614 GLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAE----AEKRREALWEKNTHLEAQLQ 669
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K E+ + + ++++ +Q ++ E + Q E T Q + Q+ + + RA+Q
Sbjct: 670 KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQ 729
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQA-----KIIE---LEKSKPNPDLPTEREI 442
E+ + + + L+ R + +D ++ E+LQ +++E E + N + +
Sbjct: 730 EKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKG- 788
Query: 443 DLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK-LAAELLNKEEIIGKMQIQTRE 501
L ++Q + V + EV K E ++E Q++ AA L + E GK ++ ++
Sbjct: 789 QLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQK 848
Query: 502 LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVH 561
++N+ + E++ ++ H + +A ES L++E M+L+M+L +
Sbjct: 849 AAHEKEVNQLR----EKWEKERSWHQQELAKALES--------LEREKMELEMRLKE--- 893
Query: 562 RNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLKNKETE---QSRELAALQQ 617
+ E+ I A++++E Q + + Q K R L+ L + E S++L L+Q
Sbjct: 894 QQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQ 953
Query: 618 DLE 620
D++
Sbjct: 954 DMK 956
Score = 61.3 bits (142), Expect = 1e-08
Identities = 75/410 (18%), Positives = 178/410 (43%), Gaps = 14/410 (3%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
+E+ L+Q+ + + ++E + ALE+ L E KE+ E +
Sbjct: 1817 QELEALQQEQQQAQGQEERVKEKADALQG--ALEQAHMTLKERHGELQDHKEQARRLEEE 1874
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVT 342
L RV +++ L + A + L+ Q ++ + E R L++S +
Sbjct: 1875 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAV 1934
Query: 343 TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL 402
+ Q+ ++L+AE + Q E ++ + L+E L + ALQ + + + EL
Sbjct: 1935 LKERDQELEALRAESQSSRHQEEAA----RARAEALQEALGKAHAALQGKEQHLLEQAEL 1990
Query: 403 KERTETELQDSRNAIEELQAKIIELEKS-KPNPDLPTEREIDLWAELQATKETLRVTEDE 461
E + +++ QA +LE++ + ++++ ++Q ++ L DE
Sbjct: 1991 SRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQAL-AQRDE 2049
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIG--KMQIQTRELIKNIKLNEQKVIQYEQY 519
++E+E + + Q++ ++ +++ +G + + + R L ++++ + + Q EQ
Sbjct: 2050 ELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQE 2109
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
+ +L+ + N + P+ S++ E LK+ L+ + E A + E +
Sbjct: 2110 ILELR-ETQQRNNLEALPH--SHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEARE 2166
Query: 580 QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEV 629
+ + Q + + + +V +E + + L++D E + R+ DE+
Sbjct: 2167 IEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSE-QQRLQDEL 2215
Score = 60.9 bits (141), Expect = 1e-08
Identities = 106/478 (22%), Positives = 203/478 (42%), Gaps = 50/478 (10%)
Query: 219 EALVREVAKLRQDVETRN--VMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEK- 275
E L R+ L QD+E R+ +M+ + R E + T+ + + +L++ KL+++E+
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQ---IKLSLRERG 1696
Query: 276 -LTTTESQLRQTRNRVAK------------MDKQLREAEASITSLTGTVKMLEDQSRQKE 322
TT+ QL Q R K M LR+ E + + L++ Q E
Sbjct: 1697 RELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLE 1756
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDL 382
QL+ RK+ E TS L+ QR+ E++ +QQ+++ Q + Q L+ L
Sbjct: 1757 QQLQGLHRKVGE--------TSLLLSQREQ---EIVVLQQQLQEAREQGELKEQSLQSQL 1805
Query: 383 KQTKRAL---QEQCEITKREIELKERTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPT 438
+ +RAL ++ E ++E + + E +++ +A++ L+ + L++
Sbjct: 1806 DEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHK 1865
Query: 439 EREIDLWAELQATKETLRVTEDEVTTCKREKESENK--IGIQQKLAAELLNKEEIIGKMQ 496
E+ L EL ++ E+ + + E + K + +QQ+ A + E +Q
Sbjct: 1866 EQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQ 1925
Query: 497 ---IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLK 553
+Q + ++K + + Q R + R A + G ++ LQ + +
Sbjct: 1926 DSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGK----E 1981
Query: 554 MKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI--NVLKNKETEQSRE 611
LL+ + L A L+ +SR ++I+E I L+ +E Q +
Sbjct: 1982 QHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQ 2041
Query: 612 LAALQQD--LEHRMRIVDEVNKQIAAKADE--IQE-LFATLENKQQQIHRLEKIVLAL 664
A Q+D L H+ + K +A + E IQE E ++++I L + V L
Sbjct: 2042 QALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVREL 2099
Score = 58.0 bits (134), Expect = 1e-07
Identities = 120/570 (21%), Positives = 249/570 (43%), Gaps = 52/570 (9%)
Query: 118 QEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYND 177
+E A+ +RD +A+ E++ LL + M ++ ++ K+ L V QD + + + +
Sbjct: 981 KEAARQHRDDLAALQEESS-SLLQDKMDLQKQVEDLKSQL-VAQDDSQRLVEQEVQEKLR 1038
Query: 178 QGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR--EVAKLRQDVETR 235
+ E +EL + E A T++ + K E+R L+ +R E++ LRQD++
Sbjct: 1039 ETQEYNRIQKEL--EREKASLTLSLMEK----EQRLLVLQEADSIRQQELSALRQDMQEA 1092
Query: 236 NVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQT----RNRV 290
E +EL ++ E + ++E + + L E TE QLR + +
Sbjct: 1093 Q---GEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKA 1149
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
A++ +LR E+ + +L + Q + QL + L+++L + + +L
Sbjct: 1150 AQLQLRLRSTESQLEALAA--EQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGG 1207
Query: 351 DSLQAEV-LECKQQ-----------IEKLTVQH-KSAIQQLEEDL---KQTKRALQEQCE 394
DS + LE Q + L+ + SA+ +L +DL +QT+ L++Q
Sbjct: 1208 DSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQ-- 1265
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET 454
+ K E L + TE E +++LQ ++ + ++ K + ++ L +EL ET
Sbjct: 1266 VQKLEERLTD-TEAEKSQVHTELQDLQRQLSQNQEEKSKWE---GKQNSLESELMELHET 1321
Query: 455 LRVTEDEVTTCKREK-ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ + + + ++ E++ + + Q L + E + ++ R + E+ +
Sbjct: 1322 MASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDL 1381
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQD----LQQEIMDLKMKLL-DVVHRNEELSE 568
L+ N + + +E + Q Q + + + LL + EE E
Sbjct: 1382 RTARSA---LKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVE 1438
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L + QELE+Q + + ++ + + N + + EQ +EL + LEH V E
Sbjct: 1439 TLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQE 1498
Query: 629 VNKQIAAKADEIQELFATLENKQQQI-HRL 657
+++ + ++I+EL E ++ + H+L
Sbjct: 1499 REQKLTVQREQIRELEKDRETQRNVLEHQL 1528
Score = 55.2 bits (127), Expect = 7e-07
Identities = 105/535 (19%), Positives = 222/535 (41%), Gaps = 38/535 (7%)
Query: 133 PENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQ 192
P L LL +T +E L Q ++ GD+ + + D+ EL L + + Q
Sbjct: 243 PAQLLLLLAKTQELEKEAHERSQELI--QLKSQGDLEK--AELQDRVTELSALLTQSQKQ 298
Query: 193 AEDAVNTVTDLSKRA--CHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESE 250
ED + L + T + EA + A+ + + + V+ D + + E +
Sbjct: 299 NEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQ-EEKLSLQQVIKDITQVMVEEGD 357
Query: 251 NTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGT 310
N + HE E + + + + L R+ + + + +++ +
Sbjct: 358 NIA--QGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEA 415
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
V +L+ Q Q E + +A ++L++ TGE RD+L + ++ + +++ L+ +
Sbjct: 416 VNLLQQQHDQWEEEGKALRQRLQKL--TGE---------RDTLAGQTVDLQGEVDSLS-K 463
Query: 371 HKSAIQQLEEDLKQTKRAL-QEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEK 429
+ +Q+ E+L+Q L QE + + +EL+ + ++ + EEL + E E+
Sbjct: 464 ERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEDQQEELHLAVRERER 523
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREK-ESENKIGIQQKLAAELLNK 488
+ ++ + +EL +E L + E ++E+ E + ++ AEL +
Sbjct: 524 LQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSS 583
Query: 489 EEIIGKMQIQTR-ELIKNIKLNEQKVIQ---YEQYVRDLQAHNRTIANCQESPNGISYQD 544
E + R +K LNE + Q + L+ N+++ + E+
Sbjct: 584 ENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEA-------- 635
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKN 603
+Q L++ L + R E L E + +L++ ++ + QA + I+EE + K
Sbjct: 636 AEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKK 695
Query: 604 -KETEQSRELAALQ-QDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
E+ +E A Q + L + +EV + + + + A LE + Q + R
Sbjct: 696 LSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVER 750
Score = 53.6 bits (123), Expect = 2e-06
Identities = 103/507 (20%), Positives = 213/507 (42%), Gaps = 62/507 (12%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVE---TRNVMIDEIR-- 243
L+TQ ++A + + +++ + L +L+++ L++ VE ++ V D+ +
Sbjct: 969 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL 1028
Query: 244 ---ELRSESENTKALEEMRHELDEER---TAKLAIKEKLTTTESQLRQTRNR-VAKMDKQ 296
E++ + T+ ++ EL+ E+ T L KE+ + R + ++ + +
Sbjct: 1029 VEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQD 1088
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL-----IQQRD 351
++EA+ L+ +++L + ++KE A+ +L E L+ +T QL Q+
Sbjct: 1089 MQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAK 1148
Query: 352 S--LQAEVLECKQQIEKLTVQHKSAIQ-QLEEDLKQTKRALQEQC-EITKREIELKERTE 407
+ LQ + + Q+E L + + Q Q + L ALQ+ + + EL +
Sbjct: 1149 AAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGD 1208
Query: 408 TE-----LQDSRNAIEEL--QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
+ L+ +N L + ++ ++ + DLW + Q T++ LR D
Sbjct: 1209 SAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLW-KTQQTRDVLR---D 1264
Query: 461 EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYV 520
+V QKL L + E ++ + ++L + + N+++ ++E
Sbjct: 1265 QV----------------QKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQ 1308
Query: 521 RDLQAHNRTIANCQES-PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
L++ + S + + +LQ+ + +LL N L + + L+
Sbjct: 1309 NSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKEN------LTAQVEHLQA 1362
Query: 580 QDKNSRGQARVIKIREELINV------LKNKETEQSRELA-ALQQDLEHRMRIVDEVNKQ 632
+R QA I EE + LKN+E E RE A ALQ+ E ++ + +
Sbjct: 1363 AVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQEN 1422
Query: 633 IAAKADEIQELFATLENKQQQIHRLEK 659
+A + E +E + QI LEK
Sbjct: 1423 LALLTQTLAEREEEVETLRGQIQELEK 1449
Score = 47.2 bits (107), Expect = 2e-04
Identities = 100/489 (20%), Positives = 197/489 (40%), Gaps = 44/489 (8%)
Query: 177 DQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN 236
DQ E A + E+A + + A + + E + E A+L + +E
Sbjct: 1939 DQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEAST 1998
Query: 237 VMIDEIRELRSESENTKALEE-MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
+ L + +++ LEE +R + E + L +E + + L Q + +
Sbjct: 1999 ATLQA--SLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQE 2056
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ----LIQQRD 351
+ + E S+ + E Q+ +E + E R L +S++ ++T +Q +++ R+
Sbjct: 2057 REQLLEKSLAQRVQENMIQEKQNLGQERE-EEEIRGLHQSVRELQLTLAQKEQEILELRE 2115
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQ--QLEEDLKQTKRALQEQCEITK-REIELKERTET 408
+ Q LE K + + +++ LE L++ LQ T+ REIE +E+ +
Sbjct: 2116 TQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQD 2175
Query: 409 ---ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE--DEVT 463
L ++ ++ LQ + L+ S D +R D EL+ T+ L
Sbjct: 2176 LALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQD---ELELTRRALEKERLHSPGA 2232
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
T E S + G+Q + + + G + R+ ++++ +Q V + E L
Sbjct: 2233 TSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHL---QQAVARLEIDRSRL 2289
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNE-ELSEILAKKDQELEQQ-D 581
Q HN + + E +++E LK + + E+S+ A + + +
Sbjct: 2290 QRHNVQLRSTLEQ--------VERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQ 2341
Query: 582 KNSRG------QARVIKIREELINVLKNKE------TEQSRELAALQQDLEHRMRIVDEV 629
KNS Q V+ ++ +L K K+ + SRELA L L H + V +
Sbjct: 2342 KNSDAKCVAELQKEVVLLQAQLTLERKQKQDYITRSAQTSRELAGLHHSLSHSLLAVAQA 2401
Query: 630 NKQIAAKAD 638
+ +A+
Sbjct: 2402 PEATVLEAE 2410
Score = 42.3 bits (95), Expect = 0.006
Identities = 73/379 (19%), Positives = 159/379 (41%), Gaps = 31/379 (8%)
Query: 178 QGFELCGALRELKTQAEDAVNTVTDLSKRACHER-RTLIAVGEALVREVAKLRQDVETRN 236
QG L E N+V +++K + +T+ E + EV L+ +++T
Sbjct: 760 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819
Query: 237 VMIDEIREL------RSESENTKALEEMR--HELDEERTAKLAIKEKLTTTES---QLRQ 285
++ R+ ++E E ALE+ + HE + + + KE+ + L
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALES 879
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+++ +L+E + + ++ + Q+ Q++ K R SL + T +
Sbjct: 880 LEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQK 939
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAI-----QQLEEDLKQTKRALQEQCEITKREI 400
+ S Q E L +++KL Q + I Q+ + +LK+ R Q + ++ +
Sbjct: 940 ELADA-SQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAAR--QHRDDLAALQE 996
Query: 401 ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
E + ++ D + +E+L+++++ + S+ + + ++ E ++ L +
Sbjct: 997 ESSSLLQDKM-DLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKA 1055
Query: 461 EVTTCKREKE------SENKIGIQQKLAAELLNKEEIIG---KMQIQTRELIKNIKLNEQ 511
+T EKE E QQ+L+A + +E G ++ Q L + +K E
Sbjct: 1056 SLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEA 1115
Query: 512 KVIQYE-QYVRDLQAHNRT 529
+ E Q + +L+A + T
Sbjct: 1116 DFLAQEAQLLEELEASHIT 1134
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 91.1 bits (216), Expect = 1e-17
Identities = 109/495 (22%), Positives = 221/495 (44%), Gaps = 32/495 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
R+L+ A D + DL + + L E L +A+L ++ +N + +IREL
Sbjct: 172 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 231
Query: 247 SE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
S+ + L+ R ++ K + E+L +++L T + A + + E +T
Sbjct: 232 GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 291
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L K L++++R E Q++ +K +++ E T QL +Q +A + + KQ +E
Sbjct: 292 VLK---KALDEETRSHEAQVQEMRQKHAQAV---EELTEQL-EQFKRAKANLDKNKQTLE 344
Query: 366 KLTVQHKSAIQ---QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
K ++ Q +++++ K+ L+ Q + + + ER EL D + ++
Sbjct: 345 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 404
Query: 423 KIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDE---VTTCKREKESENKIGIQ 478
+ + + +++ L ++LQ T+E L+ + V+T R+ E E +Q
Sbjct: 405 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN-SLQ 463
Query: 479 QKLAAELLNKEEI---IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+L E+ K+ + I + IQ + K ++ V E+ + Q + Q
Sbjct: 464 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ-QY 522
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVV---HRNEELSEILAKKDQELEQ---QDKNSRGQAR 589
+Y L++ L+ +L D+V +L L KK ++ +Q ++KN +
Sbjct: 523 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 582
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ R E + KET+ AL++ LE + + + NK + A E+++L ++ ++
Sbjct: 583 DERDRAEA--EAREKETKALSLARALEEALEAKEEL-ERTNKMLKA---EMEDLVSSKDD 636
Query: 650 KQQQIHRLEKIVLAL 664
+ +H LEK AL
Sbjct: 637 VGKNVHELEKSKRAL 651
Score = 72.5 bits (170), Expect = 5e-12
Identities = 112/542 (20%), Positives = 221/542 (40%), Gaps = 47/542 (8%)
Query: 162 DQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL 221
++ ++ + + + ++ + G L E + +A V LS + + L
Sbjct: 386 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 445
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTE 280
+ KLRQ E RN + D++ E +N + + + +L + + + E
Sbjct: 446 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 505
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE----------DQSRQKEVQLEARAR 330
++ + + + +Q E A+ L T L+ D RQ LE + R
Sbjct: 506 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQR 565
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K + L + +S+ +RD +AE E + + L + A+ + +E+L++T + L+
Sbjct: 566 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLK 624
Query: 391 EQCE--------ITKREIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD---- 435
+ E + K EL K ET++++ + +EEL+ ++ E +K +
Sbjct: 625 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASEDAKLRLEVNMQ 684
Query: 436 -LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKE 489
L + E DL A + +E R + ++ + E E E ++KL +L + E
Sbjct: 685 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKKKLEGDLKDLE 744
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQE 548
E IK ++ + ++ +++ + D +A + A +E N + L+ +
Sbjct: 745 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEAD 802
Query: 549 IMDLKMKLLDVVH-------RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINV 600
+M L+ L EEL+E LA QD+ R +AR+ ++ EEL
Sbjct: 803 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 862
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEK 659
N E R A QQ + + E + A K + Q+L + + ++H +E
Sbjct: 863 QGNMEAMSDRVRKATQQAEQLSNELATE--RSTAQKNESARQQLERQNKELRSKLHEMEG 920
Query: 660 IV 661
V
Sbjct: 921 AV 922
Score = 71.7 bits (168), Expect = 8e-12
Identities = 77/348 (22%), Positives = 153/348 (43%), Gaps = 11/348 (3%)
Query: 313 MLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHK 372
+L++Q Q E +L A A ++R L + +++ + ++ E + QQ++ +
Sbjct: 5 LLQEQL-QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMA 63
Query: 373 SAIQQLEEDLKQTKRALQE-QCEITKREIELKE-RTETELQDSRNAIEELQAKIIELEKS 430
+ LEE L++ + A Q+ Q E E ++K+ E + D +N + K++E S
Sbjct: 64 QQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERIS 123
Query: 431 KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE 490
+L E E K ++E EV K EK + +++KL + + E
Sbjct: 124 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 183
Query: 491 IIGKMQIQTREL-IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI 549
I +Q Q EL ++ K E+ + ++ N + +E IS DLQ+++
Sbjct: 184 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS--DLQEDL 241
Query: 550 MDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
+ + +L E L ELE ++ Q + RE+ + VLK E++
Sbjct: 242 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 301
Query: 610 RELAALQQDLEHR-MRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
R A Q++ + + V+E+ +Q+ ++ + A L+ +Q + +
Sbjct: 302 RSHEAQVQEMRQKHAQAVEELTEQL----EQFKRAKANLDKNKQTLEK 345
Score = 69.3 bits (162), Expect = 4e-11
Identities = 94/428 (21%), Positives = 187/428 (43%), Gaps = 37/428 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ E+ E E EE R + + K+A +++ E QL + K+ + A
Sbjct: 33 ELEEILHEMEARLEEEEDRGQQLQAERKKMA--QQMLDLEEQLEEEEAARQKLQLEKVTA 90
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
EA I L + +++DQ+ + ++ RKL E + ++TT+ AE E
Sbjct: 91 EAKIKKLEDEILVMDDQNNKL-----SKERKLLEE-RISDLTTN---------LAEEEEK 135
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
+ + KL +H+S I +LE LK+ +++ Q E+ K LK + E + D I +L
Sbjct: 136 AKNLTKLKNKHESMISELEVRLKKEEKSRQ---ELEK----LKRKLEGDASDFHEQIADL 188
Query: 421 QAKIIELE----KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG 476
QA+I EL+ K + R D A+ + +R E ++ + + +SE
Sbjct: 189 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER--A 246
Query: 477 IQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQES 536
+ K + + E + ++ + + + + ++ + EQ V L+ E+
Sbjct: 247 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 306
Query: 537 PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREE 596
Q+++Q+ +L + + + + L K Q LE+++ + G+ RV+ ++
Sbjct: 307 ----QVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 362
Query: 597 LINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ K K Q +EL + D E R E+N ++ +E++ + L + + +
Sbjct: 363 EVEHKKKKLEAQVQELQSKCSDGE---RARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 419
Query: 657 LEKIVLAL 664
L K V +L
Sbjct: 420 LAKDVASL 427
Score = 52.8 bits (121), Expect = 4e-06
Identities = 53/216 (24%), Positives = 99/216 (45%), Gaps = 16/216 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELD---EERTAKLAIKEKLTTTESQLRQ 285
++ +E R ++E EL E N +A+ + + E+ + +LA + RQ
Sbjct: 845 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 902
Query: 286 TRNRVAK-MDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R K + +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 903 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 957
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 958 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1014
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
+ + EL ++ + E + ++ L KSK P E
Sbjct: 1015 RKLQRELDEATESNEAMGREVNAL-KSKLRGPPPQE 1049
Score = 48.8 bits (111), Expect = 6e-05
Identities = 44/204 (21%), Positives = 96/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 787 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 841
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 842 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 897
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 898 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 957
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 958 LKQKDKKLKEILLQVEDERKMAEQ 981
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 91.1 bits (216), Expect = 1e-17
Identities = 109/495 (22%), Positives = 221/495 (44%), Gaps = 32/495 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
R+L+ A D + DL + + L E L +A+L ++ +N + +IREL
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1117
Query: 247 SE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
S+ + L+ R ++ K + E+L +++L T + A + + E +T
Sbjct: 1118 GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1177
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L K L++++R E Q++ +K +++ E T QL +Q +A + + KQ +E
Sbjct: 1178 VLK---KALDEETRSHEAQVQEMRQKHAQAV---EELTEQL-EQFKRAKANLDKNKQTLE 1230
Query: 366 KLTVQHKSAIQ---QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
K ++ Q +++++ K+ L+ Q + + + ER EL D + ++
Sbjct: 1231 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1290
Query: 423 KIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDE---VTTCKREKESENKIGIQ 478
+ + + +++ L ++LQ T+E L+ + V+T R+ E E +Q
Sbjct: 1291 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN-SLQ 1349
Query: 479 QKLAAELLNKEEI---IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+L E+ K+ + I + IQ + K ++ V E+ + Q + Q
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ-QY 1408
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVV---HRNEELSEILAKKDQELEQ---QDKNSRGQAR 589
+Y L++ L+ +L D+V +L L KK ++ +Q ++KN +
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ R E + KET+ AL++ LE + + + NK + A E+++L ++ ++
Sbjct: 1469 DERDRAEA--EAREKETKALSLARALEEALEAKEEL-ERTNKMLKA---EMEDLVSSKDD 1522
Query: 650 KQQQIHRLEKIVLAL 664
+ +H LEK AL
Sbjct: 1523 VGKNVHELEKSKRAL 1537
Score = 74.9 bits (176), Expect = 9e-13
Identities = 113/542 (20%), Positives = 222/542 (40%), Gaps = 47/542 (8%)
Query: 162 DQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL 221
++ ++ + + + ++ + G L E + +A V LS + + L
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTE 280
+ KLRQ E RN + D++ E +N + + + +L + + + E
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE----------DQSRQKEVQLEARAR 330
++ + + + +Q E A+ L T L+ D RQ LE + R
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQR 1451
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K + L + +S+ +RD +AE E + + L + A+ + +E+L++T + L+
Sbjct: 1452 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLK 1510
Query: 391 EQCE--------ITKREIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD---- 435
+ E + K EL K ET++++ + +EEL+ ++ E +K +
Sbjct: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 436 -LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKE 489
L + E DL A + +E R + ++ + E E E K ++KL +L + E
Sbjct: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQE 548
E IK ++ + ++ +++ + D +A + A +E N + L+ +
Sbjct: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEAD 1688
Query: 549 IMDLKMKLLDVVH-------RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINV 600
+M L+ L EEL+E LA QD+ R +AR+ ++ EEL
Sbjct: 1689 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1748
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEK 659
N E R A QQ + + E + A K + Q+L + + ++H +E
Sbjct: 1749 QGNMEAMSDRVRKATQQAEQLSNELATE--RSTAQKNESARQQLERQNKELRSKLHEMEG 1806
Query: 660 IV 661
V
Sbjct: 1807 AV 1808
Score = 70.5 bits (165), Expect = 2e-11
Identities = 91/403 (22%), Positives = 178/403 (44%), Gaps = 41/403 (10%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ----------SRQKE 322
+E++ E +L++T+ R K + +L+E E + LT +L++Q + +
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE-------VLECKQQIEKLTVQHKSAI 375
V+L A+ ++L E L E + + LQAE +L+ ++Q+E + ++A
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAAR 966
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPD 435
Q+L+ + K T A +I K E E+ + D N + + + K++E S +
Sbjct: 967 QKLQLE-KVTAEA-----KIKKLEDEI-----LVMDDQNNKLSK-ERKLLEERISDLTTN 1014
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
L E E K ++E EV K EK + +++KL + + E I +
Sbjct: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
Query: 496 QIQTREL-IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
Q Q EL ++ K E+ + ++ N + +E IS DLQ+++ +
Sbjct: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS--DLQEDLDSERA 1132
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ +L E L ELE ++ Q + RE+ + VLK E++R A
Sbjct: 1133 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1192
Query: 615 LQQDLEHR-MRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
Q++ + + V+E+ +Q+ ++ + A L+ +Q + +
Sbjct: 1193 QVQEMRQKHAQAVEELTEQL----EQFKRAKANLDKNKQTLEK 1231
Score = 52.8 bits (121), Expect = 4e-06
Identities = 53/216 (24%), Positives = 99/216 (45%), Gaps = 16/216 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELD---EERTAKLAIKEKLTTTESQLRQ 285
++ +E R ++E EL E N +A+ + + E+ + +LA + RQ
Sbjct: 1731 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1788
Query: 286 TRNRVAK-MDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R K + +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 1789 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 1843
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 1844 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1900
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
+ + EL ++ + E + ++ L KSK P E
Sbjct: 1901 RKLQRELDEATESNEAMGREVNAL-KSKLRGPPPQE 1935
Score = 48.8 bits (111), Expect = 6e-05
Identities = 44/204 (21%), Positives = 96/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 1673 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 1727
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 1783
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 1784 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1843
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 1844 LKQKDKKLKEILLQVEDERKMAEQ 1867
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/311 (24%), Positives = 144/311 (46%), Gaps = 33/311 (10%)
Query: 370 QHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE----LQDSRNAIEE------ 419
+ + +Q E++L++TK Q++ E +E+E K TE LQ+ A E
Sbjct: 849 RQEEEMQAKEDELQKTKER-QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907
Query: 420 -----LQAKIIELEKSKPNPDLPTEREIDLWAELQA-TKETLRVTEDEVTTCKREKESEN 473
L AK ELE+ + E E D +LQA K+ + D + E+ +
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 474 KIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNIKLNEQKV-------IQYEQYVRDL-Q 524
K+ +++ A A++ E+ I M Q +L K KL E+++ + E+ ++L +
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Query: 525 AHNRTIANCQESPNGISYQD-LQQEIMDLKMKLL-DVVHRNEELSEILAK-KDQELEQQD 581
N+ + E + ++ +QE+ LK KL D +E+++++ A+ + +++
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087
Query: 582 KNSRGQARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
K QA + ++ +E+ N LK K E ++ LQ+DL+ ++ KQ +
Sbjct: 1088 KEEELQAALARLDDEIAQKNNALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146
Query: 639 EIQELFATLEN 649
E++ L LE+
Sbjct: 1147 ELEALKTELED 1157
Score = 31.9 bits (69), Expect = 7.9
Identities = 19/88 (21%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Query: 570 LAKKDQELE-QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI--- 625
+ ++++E++ ++D+ + + R K EL L+ K ++ + E LQ+ L+ +
Sbjct: 847 VTRQEEEMQAKEDELQKTKERQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQ 653
+E+ ++AAK E++E+ +E + ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEE 933
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 91.1 bits (216), Expect = 1e-17
Identities = 109/495 (22%), Positives = 221/495 (44%), Gaps = 32/495 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
R+L+ A D + DL + + L E L +A+L ++ +N + +IREL
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1117
Query: 247 SE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
S+ + L+ R ++ K + E+L +++L T + A + + E +T
Sbjct: 1118 GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1177
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L K L++++R E Q++ +K +++ E T QL +Q +A + + KQ +E
Sbjct: 1178 VLK---KALDEETRSHEAQVQEMRQKHAQAV---EELTEQL-EQFKRAKANLDKNKQTLE 1230
Query: 366 KLTVQHKSAIQ---QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
K ++ Q +++++ K+ L+ Q + + + ER EL D + ++
Sbjct: 1231 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1290
Query: 423 KIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDE---VTTCKREKESENKIGIQ 478
+ + + +++ L ++LQ T+E L+ + V+T R+ E E +Q
Sbjct: 1291 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN-SLQ 1349
Query: 479 QKLAAELLNKEEI---IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+L E+ K+ + I + IQ + K ++ V E+ + Q + Q
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ-QY 1408
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVV---HRNEELSEILAKKDQELEQ---QDKNSRGQAR 589
+Y L++ L+ +L D+V +L L KK ++ +Q ++KN +
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ R E + KET+ AL++ LE + + + NK + A E+++L ++ ++
Sbjct: 1469 DERDRAEA--EAREKETKALSLARALEEALEAKEEL-ERTNKMLKA---EMEDLVSSKDD 1522
Query: 650 KQQQIHRLEKIVLAL 664
+ +H LEK AL
Sbjct: 1523 VGKNVHELEKSKRAL 1537
Score = 74.9 bits (176), Expect = 9e-13
Identities = 113/542 (20%), Positives = 222/542 (40%), Gaps = 47/542 (8%)
Query: 162 DQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL 221
++ ++ + + + ++ + G L E + +A V LS + + L
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTE 280
+ KLRQ E RN + D++ E +N + + + +L + + + E
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE----------DQSRQKEVQLEARAR 330
++ + + + +Q E A+ L T L+ D RQ LE + R
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQR 1451
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K + L + +S+ +RD +AE E + + L + A+ + +E+L++T + L+
Sbjct: 1452 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLK 1510
Query: 391 EQCE--------ITKREIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD---- 435
+ E + K EL K ET++++ + +EEL+ ++ E +K +
Sbjct: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 436 -LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKE 489
L + E DL A + +E R + ++ + E E E K ++KL +L + E
Sbjct: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQE 548
E IK ++ + ++ +++ + D +A + A +E N + L+ +
Sbjct: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEAD 1688
Query: 549 IMDLKMKLLDVVH-------RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINV 600
+M L+ L EEL+E LA QD+ R +AR+ ++ EEL
Sbjct: 1689 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1748
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEK 659
N E R A QQ + + E + A K + Q+L + + ++H +E
Sbjct: 1749 QGNMEAMSDRVRKATQQAEQLSNELATE--RSTAQKNESARQQLERQNKELRSKLHEMEG 1806
Query: 660 IV 661
V
Sbjct: 1807 AV 1808
Score = 70.5 bits (165), Expect = 2e-11
Identities = 91/403 (22%), Positives = 178/403 (44%), Gaps = 41/403 (10%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ----------SRQKE 322
+E++ E +L++T+ R K + +L+E E + LT +L++Q + +
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE-------VLECKQQIEKLTVQHKSAI 375
V+L A+ ++L E L E + + LQAE +L+ ++Q+E + ++A
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAAR 966
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPD 435
Q+L+ + K T A +I K E E+ + D N + + + K++E S +
Sbjct: 967 QKLQLE-KVTAEA-----KIKKLEDEI-----LVMDDQNNKLSK-ERKLLEERISDLTTN 1014
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
L E E K ++E EV K EK + +++KL + + E I +
Sbjct: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
Query: 496 QIQTREL-IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
Q Q EL ++ K E+ + ++ N + +E IS DLQ+++ +
Sbjct: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS--DLQEDLDSERA 1132
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ +L E L ELE ++ Q + RE+ + VLK E++R A
Sbjct: 1133 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1192
Query: 615 LQQDLEHR-MRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
Q++ + + V+E+ +Q+ ++ + A L+ +Q + +
Sbjct: 1193 QVQEMRQKHAQAVEELTEQL----EQFKRAKANLDKNKQTLEK 1231
Score = 52.8 bits (121), Expect = 4e-06
Identities = 53/216 (24%), Positives = 99/216 (45%), Gaps = 16/216 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELD---EERTAKLAIKEKLTTTESQLRQ 285
++ +E R ++E EL E N +A+ + + E+ + +LA + RQ
Sbjct: 1731 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1788
Query: 286 TRNRVAK-MDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R K + +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 1789 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 1843
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 1844 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1900
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
+ + EL ++ + E + ++ L KSK P E
Sbjct: 1901 RKLQRELDEATESNEAMGREVNAL-KSKLRGPPPQE 1935
Score = 48.8 bits (111), Expect = 6e-05
Identities = 44/204 (21%), Positives = 96/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 1673 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 1727
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 1783
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 1784 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1843
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 1844 LKQKDKKLKEILLQVEDERKMAEQ 1867
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/311 (24%), Positives = 144/311 (46%), Gaps = 33/311 (10%)
Query: 370 QHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE----LQDSRNAIEE------ 419
+ + +Q E++L++TK Q++ E +E+E K TE LQ+ A E
Sbjct: 849 RQEEEMQAKEDELQKTKER-QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907
Query: 420 -----LQAKIIELEKSKPNPDLPTEREIDLWAELQA-TKETLRVTEDEVTTCKREKESEN 473
L AK ELE+ + E E D +LQA K+ + D + E+ +
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
Query: 474 KIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNIKLNEQKV-------IQYEQYVRDL-Q 524
K+ +++ A A++ E+ I M Q +L K KL E+++ + E+ ++L +
Sbjct: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Query: 525 AHNRTIANCQESPNGISYQD-LQQEIMDLKMKLL-DVVHRNEELSEILAK-KDQELEQQD 581
N+ + E + ++ +QE+ LK KL D +E+++++ A+ + +++
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087
Query: 582 KNSRGQARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
K QA + ++ +E+ N LK K E ++ LQ+DL+ ++ KQ +
Sbjct: 1088 KEEELQAALARLDDEIAQKNNALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146
Query: 639 EIQELFATLEN 649
E++ L LE+
Sbjct: 1147 ELEALKTELED 1157
Score = 31.9 bits (69), Expect = 7.9
Identities = 19/88 (21%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Query: 570 LAKKDQELE-QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI--- 625
+ ++++E++ ++D+ + + R K EL L+ K ++ + E LQ+ L+ +
Sbjct: 847 VTRQEEEMQAKEDELQKTKERQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQ 653
+E+ ++AAK E++E+ +E + ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEE 933
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 91.1 bits (216), Expect = 1e-17
Identities = 109/495 (22%), Positives = 221/495 (44%), Gaps = 32/495 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
R+L+ A D + DL + + L E L +A+L ++ +N + +IREL
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1124
Query: 247 SE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
S+ + L+ R ++ K + E+L +++L T + A + + E +T
Sbjct: 1125 GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1184
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L K L++++R E Q++ +K +++ E T QL +Q +A + + KQ +E
Sbjct: 1185 VLK---KALDEETRSHEAQVQEMRQKHAQAV---EELTEQL-EQFKRAKANLDKNKQTLE 1237
Query: 366 KLTVQHKSAIQ---QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
K ++ Q +++++ K+ L+ Q + + + ER EL D + ++
Sbjct: 1238 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1297
Query: 423 KIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDE---VTTCKREKESENKIGIQ 478
+ + + +++ L ++LQ T+E L+ + V+T R+ E E +Q
Sbjct: 1298 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN-SLQ 1356
Query: 479 QKLAAELLNKEEI---IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+L E+ K+ + I + IQ + K ++ V E+ + Q + Q
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ-QY 1415
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVV---HRNEELSEILAKKDQELEQ---QDKNSRGQAR 589
+Y L++ L+ +L D+V +L L KK ++ +Q ++KN +
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ R E + KET+ AL++ LE + + + NK + A E+++L ++ ++
Sbjct: 1476 DERDRAEA--EAREKETKALSLARALEEALEAKEEL-ERTNKMLKA---EMEDLVSSKDD 1529
Query: 650 KQQQIHRLEKIVLAL 664
+ +H LEK AL
Sbjct: 1530 VGKNVHELEKSKRAL 1544
Score = 74.9 bits (176), Expect = 9e-13
Identities = 113/542 (20%), Positives = 222/542 (40%), Gaps = 47/542 (8%)
Query: 162 DQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL 221
++ ++ + + + ++ + G L E + +A V LS + + L
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTE 280
+ KLRQ E RN + D++ E +N + + + +L + + + E
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE----------DQSRQKEVQLEARAR 330
++ + + + +Q E A+ L T L+ D RQ LE + R
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQR 1458
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K + L + +S+ +RD +AE E + + L + A+ + +E+L++T + L+
Sbjct: 1459 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLK 1517
Query: 391 EQCE--------ITKREIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD---- 435
+ E + K EL K ET++++ + +EEL+ ++ E +K +
Sbjct: 1518 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1577
Query: 436 -LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKE 489
L + E DL A + +E R + ++ + E E E K ++KL +L + E
Sbjct: 1578 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1637
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQE 548
E IK ++ + ++ +++ + D +A + A +E N + L+ +
Sbjct: 1638 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEAD 1695
Query: 549 IMDLKMKLLDVVH-------RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINV 600
+M L+ L EEL+E LA QD+ R +AR+ ++ EEL
Sbjct: 1696 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1755
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEK 659
N E R A QQ + + E + A K + Q+L + + ++H +E
Sbjct: 1756 QGNMEAMSDRVRKATQQAEQLSNELATE--RSTAQKNESARQQLERQNKELRSKLHEMEG 1813
Query: 660 IV 661
V
Sbjct: 1814 AV 1815
Score = 70.5 bits (165), Expect = 2e-11
Identities = 91/403 (22%), Positives = 178/403 (44%), Gaps = 41/403 (10%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ----------SRQKE 322
+E++ E +L++T+ R K + +L+E E + LT +L++Q + +
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE-------VLECKQQIEKLTVQHKSAI 375
V+L A+ ++L E L E + + LQAE +L+ ++Q+E + ++A
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAAR 973
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPD 435
Q+L+ + K T A +I K E E+ + D N + + + K++E S +
Sbjct: 974 QKLQLE-KVTAEA-----KIKKLEDEI-----LVMDDQNNKLSK-ERKLLEERISDLTTN 1021
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
L E E K ++E EV K EK + +++KL + + E I +
Sbjct: 1022 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1081
Query: 496 QIQTREL-IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
Q Q EL ++ K E+ + ++ N + +E IS DLQ+++ +
Sbjct: 1082 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS--DLQEDLDSERA 1139
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ +L E L ELE ++ Q + RE+ + VLK E++R A
Sbjct: 1140 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1199
Query: 615 LQQDLEHR-MRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
Q++ + + V+E+ +Q+ ++ + A L+ +Q + +
Sbjct: 1200 QVQEMRQKHAQAVEELTEQL----EQFKRAKANLDKNKQTLEK 1238
Score = 52.8 bits (121), Expect = 4e-06
Identities = 53/216 (24%), Positives = 99/216 (45%), Gaps = 16/216 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELD---EERTAKLAIKEKLTTTESQLRQ 285
++ +E R ++E EL E N +A+ + + E+ + +LA + RQ
Sbjct: 1738 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1795
Query: 286 TRNRVAK-MDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R K + +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 1796 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 1850
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 1851 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1907
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
+ + EL ++ + E + ++ L KSK P E
Sbjct: 1908 RKLQRELDEATESNEAMGREVNAL-KSKLRGPPPQE 1942
Score = 48.8 bits (111), Expect = 6e-05
Identities = 44/204 (21%), Positives = 96/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 1680 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 1734
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 1790
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 1791 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1850
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 1851 LKQKDKKLKEILLQVEDERKMAEQ 1874
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/311 (24%), Positives = 144/311 (46%), Gaps = 33/311 (10%)
Query: 370 QHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE----LQDSRNAIEE------ 419
+ + +Q E++L++TK Q++ E +E+E K TE LQ+ A E
Sbjct: 856 RQEEEMQAKEDELQKTKER-QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 914
Query: 420 -----LQAKIIELEKSKPNPDLPTEREIDLWAELQA-TKETLRVTEDEVTTCKREKESEN 473
L AK ELE+ + E E D +LQA K+ + D + E+ +
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 474 KIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNIKLNEQKV-------IQYEQYVRDL-Q 524
K+ +++ A A++ E+ I M Q +L K KL E+++ + E+ ++L +
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Query: 525 AHNRTIANCQESPNGISYQD-LQQEIMDLKMKLL-DVVHRNEELSEILAK-KDQELEQQD 581
N+ + E + ++ +QE+ LK KL D +E+++++ A+ + +++
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094
Query: 582 KNSRGQARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
K QA + ++ +E+ N LK K E ++ LQ+DL+ ++ KQ +
Sbjct: 1095 KEEELQAALARLDDEIAQKNNALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1153
Query: 639 EIQELFATLEN 649
E++ L LE+
Sbjct: 1154 ELEALKTELED 1164
Score = 31.9 bits (69), Expect = 7.9
Identities = 19/88 (21%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Query: 570 LAKKDQELE-QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI--- 625
+ ++++E++ ++D+ + + R K EL L+ K ++ + E LQ+ L+ +
Sbjct: 854 VTRQEEEMQAKEDELQKTKERQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQ 653
+E+ ++AAK E++E+ +E + ++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEE 940
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 91.1 bits (216), Expect = 1e-17
Identities = 109/495 (22%), Positives = 221/495 (44%), Gaps = 32/495 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
R+L+ A D + DL + + L E L +A+L ++ +N + +IREL
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1124
Query: 247 SE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
S+ + L+ R ++ K + E+L +++L T + A + + E +T
Sbjct: 1125 GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1184
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L K L++++R E Q++ +K +++ E T QL +Q +A + + KQ +E
Sbjct: 1185 VLK---KALDEETRSHEAQVQEMRQKHAQAV---EELTEQL-EQFKRAKANLDKNKQTLE 1237
Query: 366 KLTVQHKSAIQ---QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
K ++ Q +++++ K+ L+ Q + + + ER EL D + ++
Sbjct: 1238 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1297
Query: 423 KIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDE---VTTCKREKESENKIGIQ 478
+ + + +++ L ++LQ T+E L+ + V+T R+ E E +Q
Sbjct: 1298 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN-SLQ 1356
Query: 479 QKLAAELLNKEEI---IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+L E+ K+ + I + IQ + K ++ V E+ + Q + Q
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ-QY 1415
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVV---HRNEELSEILAKKDQELEQ---QDKNSRGQAR 589
+Y L++ L+ +L D+V +L L KK ++ +Q ++KN +
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ R E + KET+ AL++ LE + + + NK + A E+++L ++ ++
Sbjct: 1476 DERDRAEA--EAREKETKALSLARALEEALEAKEEL-ERTNKMLKA---EMEDLVSSKDD 1529
Query: 650 KQQQIHRLEKIVLAL 664
+ +H LEK AL
Sbjct: 1530 VGKNVHELEKSKRAL 1544
Score = 74.9 bits (176), Expect = 9e-13
Identities = 113/542 (20%), Positives = 222/542 (40%), Gaps = 47/542 (8%)
Query: 162 DQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL 221
++ ++ + + + ++ + G L E + +A V LS + + L
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTE 280
+ KLRQ E RN + D++ E +N + + + +L + + + E
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE----------DQSRQKEVQLEARAR 330
++ + + + +Q E A+ L T L+ D RQ LE + R
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQR 1458
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K + L + +S+ +RD +AE E + + L + A+ + +E+L++T + L+
Sbjct: 1459 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLK 1517
Query: 391 EQCE--------ITKREIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD---- 435
+ E + K EL K ET++++ + +EEL+ ++ E +K +
Sbjct: 1518 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1577
Query: 436 -LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKE 489
L + E DL A + +E R + ++ + E E E K ++KL +L + E
Sbjct: 1578 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1637
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQE 548
E IK ++ + ++ +++ + D +A + A +E N + L+ +
Sbjct: 1638 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEAD 1695
Query: 549 IMDLKMKLLDVVH-------RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINV 600
+M L+ L EEL+E LA QD+ R +AR+ ++ EEL
Sbjct: 1696 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1755
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEK 659
N E R A QQ + + E + A K + Q+L + + ++H +E
Sbjct: 1756 QGNMEAMSDRVRKATQQAEQLSNELATE--RSTAQKNESARQQLERQNKELRSKLHEMEG 1813
Query: 660 IV 661
V
Sbjct: 1814 AV 1815
Score = 70.5 bits (165), Expect = 2e-11
Identities = 91/403 (22%), Positives = 178/403 (44%), Gaps = 41/403 (10%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ----------SRQKE 322
+E++ E +L++T+ R K + +L+E E + LT +L++Q + +
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE-------VLECKQQIEKLTVQHKSAI 375
V+L A+ ++L E L E + + LQAE +L+ ++Q+E + ++A
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAAR 973
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPD 435
Q+L+ + K T A +I K E E+ + D N + + + K++E S +
Sbjct: 974 QKLQLE-KVTAEA-----KIKKLEDEI-----LVMDDQNNKLSK-ERKLLEERISDLTTN 1021
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
L E E K ++E EV K EK + +++KL + + E I +
Sbjct: 1022 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1081
Query: 496 QIQTREL-IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
Q Q EL ++ K E+ + ++ N + +E IS DLQ+++ +
Sbjct: 1082 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS--DLQEDLDSERA 1139
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ +L E L ELE ++ Q + RE+ + VLK E++R A
Sbjct: 1140 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1199
Query: 615 LQQDLEHR-MRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
Q++ + + V+E+ +Q+ ++ + A L+ +Q + +
Sbjct: 1200 QVQEMRQKHAQAVEELTEQL----EQFKRAKANLDKNKQTLEK 1238
Score = 52.0 bits (119), Expect = 7e-06
Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 16/208 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELD---EERTAKLAIKEKLTTTESQLRQ 285
++ +E R ++E EL E N +A+ + + E+ + +LA + RQ
Sbjct: 1738 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1795
Query: 286 TRNRVAK-MDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R K + +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 1796 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 1850
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 1851 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1907
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSK 431
+ + EL ++ + E + ++ L KSK
Sbjct: 1908 RKLQRELDEATESNEAMGREVNAL-KSK 1934
Score = 48.8 bits (111), Expect = 6e-05
Identities = 44/204 (21%), Positives = 96/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 1680 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 1734
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 1790
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 1791 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1850
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 1851 LKQKDKKLKEILLQVEDERKMAEQ 1874
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/311 (24%), Positives = 144/311 (46%), Gaps = 33/311 (10%)
Query: 370 QHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE----LQDSRNAIEE------ 419
+ + +Q E++L++TK Q++ E +E+E K TE LQ+ A E
Sbjct: 856 RQEEEMQAKEDELQKTKER-QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 914
Query: 420 -----LQAKIIELEKSKPNPDLPTEREIDLWAELQA-TKETLRVTEDEVTTCKREKESEN 473
L AK ELE+ + E E D +LQA K+ + D + E+ +
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 974
Query: 474 KIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNIKLNEQKV-------IQYEQYVRDL-Q 524
K+ +++ A A++ E+ I M Q +L K KL E+++ + E+ ++L +
Sbjct: 975 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Query: 525 AHNRTIANCQESPNGISYQD-LQQEIMDLKMKLL-DVVHRNEELSEILAK-KDQELEQQD 581
N+ + E + ++ +QE+ LK KL D +E+++++ A+ + +++
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094
Query: 582 KNSRGQARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
K QA + ++ +E+ N LK K E ++ LQ+DL+ ++ KQ +
Sbjct: 1095 KEEELQAALARLDDEIAQKNNALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1153
Query: 639 EIQELFATLEN 649
E++ L LE+
Sbjct: 1154 ELEALKTELED 1164
Score = 31.9 bits (69), Expect = 7.9
Identities = 19/88 (21%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Query: 570 LAKKDQELE-QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI--- 625
+ ++++E++ ++D+ + + R K EL L+ K ++ + E LQ+ L+ +
Sbjct: 854 VTRQEEEMQAKEDELQKTKERQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQ 653
+E+ ++AAK E++E+ +E + ++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEE 940
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 91.1 bits (216), Expect = 1e-17
Identities = 109/495 (22%), Positives = 221/495 (44%), Gaps = 32/495 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
R+L+ A D + DL + + L E L +A+L ++ +N + +IREL
Sbjct: 943 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1002
Query: 247 SE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
S+ + L+ R ++ K + E+L +++L T + A + + E +T
Sbjct: 1003 GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1062
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L K L++++R E Q++ +K +++ E T QL +Q +A + + KQ +E
Sbjct: 1063 VLK---KALDEETRSHEAQVQEMRQKHAQAV---EELTEQL-EQFKRAKANLDKNKQTLE 1115
Query: 366 KLTVQHKSAIQ---QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
K ++ Q +++++ K+ L+ Q + + + ER EL D + ++
Sbjct: 1116 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1175
Query: 423 KIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDE---VTTCKREKESENKIGIQ 478
+ + + +++ L ++LQ T+E L+ + V+T R+ E E +Q
Sbjct: 1176 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN-SLQ 1234
Query: 479 QKLAAELLNKEEI---IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+L E+ K+ + I + IQ + K ++ V E+ + Q + Q
Sbjct: 1235 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ-QY 1293
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVV---HRNEELSEILAKKDQELEQ---QDKNSRGQAR 589
+Y L++ L+ +L D+V +L L KK ++ +Q ++KN +
Sbjct: 1294 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1353
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ R E + KET+ AL++ LE + + + NK + A E+++L ++ ++
Sbjct: 1354 DERDRAEA--EAREKETKALSLARALEEALEAKEEL-ERTNKMLKA---EMEDLVSSKDD 1407
Query: 650 KQQQIHRLEKIVLAL 664
+ +H LEK AL
Sbjct: 1408 VGKNVHELEKSKRAL 1422
Score = 74.9 bits (176), Expect = 9e-13
Identities = 113/542 (20%), Positives = 222/542 (40%), Gaps = 47/542 (8%)
Query: 162 DQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL 221
++ ++ + + + ++ + G L E + +A V LS + + L
Sbjct: 1157 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1216
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTE 280
+ KLRQ E RN + D++ E +N + + + +L + + + E
Sbjct: 1217 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1276
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE----------DQSRQKEVQLEARAR 330
++ + + + +Q E A+ L T L+ D RQ LE + R
Sbjct: 1277 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQR 1336
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K + L + +S+ +RD +AE E + + L + A+ + +E+L++T + L+
Sbjct: 1337 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLK 1395
Query: 391 EQCE--------ITKREIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD---- 435
+ E + K EL K ET++++ + +EEL+ ++ E +K +
Sbjct: 1396 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1455
Query: 436 -LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKE 489
L + E DL A + +E R + ++ + E E E K ++KL +L + E
Sbjct: 1456 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1515
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQE 548
E IK ++ + ++ +++ + D +A + A +E N + L+ +
Sbjct: 1516 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEAD 1573
Query: 549 IMDLKMKLLDVVH-------RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINV 600
+M L+ L EEL+E LA QD+ R +AR+ ++ EEL
Sbjct: 1574 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1633
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEK 659
N E R A QQ + + E + A K + Q+L + + ++H +E
Sbjct: 1634 QGNMEAMSDRVRKATQQAEQLSNELATE--RSTAQKNESARQQLERQNKELRSKLHEMEG 1691
Query: 660 IV 661
V
Sbjct: 1692 AV 1693
Score = 70.5 bits (165), Expect = 2e-11
Identities = 91/403 (22%), Positives = 178/403 (44%), Gaps = 41/403 (10%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ----------SRQKE 322
+E++ E +L++T+ R K + +L+E E + LT +L++Q + +
Sbjct: 736 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 795
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE-------VLECKQQIEKLTVQHKSAI 375
V+L A+ ++L E L E + + LQAE +L+ ++Q+E + ++A
Sbjct: 796 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAAR 851
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPD 435
Q+L+ + K T A +I K E E+ + D N + + + K++E S +
Sbjct: 852 QKLQLE-KVTAEA-----KIKKLEDEI-----LVMDDQNNKLSK-ERKLLEERISDLTTN 899
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
L E E K ++E EV K EK + +++KL + + E I +
Sbjct: 900 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 959
Query: 496 QIQTREL-IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
Q Q EL ++ K E+ + ++ N + +E IS DLQ+++ +
Sbjct: 960 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS--DLQEDLDSERA 1017
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ +L E L ELE ++ Q + RE+ + VLK E++R A
Sbjct: 1018 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1077
Query: 615 LQQDLEHR-MRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
Q++ + + V+E+ +Q+ ++ + A L+ +Q + +
Sbjct: 1078 QVQEMRQKHAQAVEELTEQL----EQFKRAKANLDKNKQTLEK 1116
Score = 52.0 bits (119), Expect = 7e-06
Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 16/208 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELD---EERTAKLAIKEKLTTTESQLRQ 285
++ +E R ++E EL E N +A+ + + E+ + +LA + RQ
Sbjct: 1616 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1673
Query: 286 TRNRVAK-MDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R K + +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 1674 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 1728
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 1729 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1785
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSK 431
+ + EL ++ + E + ++ L KSK
Sbjct: 1786 RKLQRELDEATESNEAMGREVNAL-KSK 1812
Score = 48.8 bits (111), Expect = 6e-05
Identities = 44/204 (21%), Positives = 96/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 1558 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 1612
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 1613 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 1668
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 1669 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1728
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 1729 LKQKDKKLKEILLQVEDERKMAEQ 1752
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/311 (24%), Positives = 144/311 (46%), Gaps = 33/311 (10%)
Query: 370 QHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE----LQDSRNAIEE------ 419
+ + +Q E++L++TK Q++ E +E+E K TE LQ+ A E
Sbjct: 734 RQEEEMQAKEDELQKTKER-QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 792
Query: 420 -----LQAKIIELEKSKPNPDLPTEREIDLWAELQA-TKETLRVTEDEVTTCKREKESEN 473
L AK ELE+ + E E D +LQA K+ + D + E+ +
Sbjct: 793 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 852
Query: 474 KIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNIKLNEQKV-------IQYEQYVRDL-Q 524
K+ +++ A A++ E+ I M Q +L K KL E+++ + E+ ++L +
Sbjct: 853 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 912
Query: 525 AHNRTIANCQESPNGISYQD-LQQEIMDLKMKLL-DVVHRNEELSEILAK-KDQELEQQD 581
N+ + E + ++ +QE+ LK KL D +E+++++ A+ + +++
Sbjct: 913 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 972
Query: 582 KNSRGQARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
K QA + ++ +E+ N LK K E ++ LQ+DL+ ++ KQ +
Sbjct: 973 KEEELQAALARLDDEIAQKNNALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1031
Query: 639 EIQELFATLEN 649
E++ L LE+
Sbjct: 1032 ELEALKTELED 1042
Score = 31.9 bits (69), Expect = 7.9
Identities = 19/88 (21%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Query: 570 LAKKDQELE-QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI--- 625
+ ++++E++ ++D+ + + R K EL L+ K ++ + E LQ+ L+ +
Sbjct: 732 VTRQEEEMQAKEDELQKTKERQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAE 790
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQ 653
+E+ ++AAK E++E+ +E + ++
Sbjct: 791 AEEMRVRLAAKKQELEEILHEMEARLEE 818
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 91.1 bits (216), Expect = 1e-17
Identities = 109/495 (22%), Positives = 221/495 (44%), Gaps = 32/495 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
R+L+ A D + DL + + L E L +A+L ++ +N + +IREL
Sbjct: 1070 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE 1129
Query: 247 SE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
S+ + L+ R ++ K + E+L +++L T + A + + E +T
Sbjct: 1130 GHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVT 1189
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L K L++++R E Q++ +K +++ E T QL +Q +A + + KQ +E
Sbjct: 1190 VLK---KALDEETRSHEAQVQEMRQKHAQAV---EELTEQL-EQFKRAKANLDKNKQTLE 1242
Query: 366 KLTVQHKSAIQ---QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
K ++ Q +++++ K+ L+ Q + + + ER EL D + ++
Sbjct: 1243 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1302
Query: 423 KIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDE---VTTCKREKESENKIGIQ 478
+ + + +++ L ++LQ T+E L+ + V+T R+ E E +Q
Sbjct: 1303 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN-SLQ 1361
Query: 479 QKLAAELLNKEEI---IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+L E+ K+ + I + IQ + K ++ V E+ + Q + Q
Sbjct: 1362 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ-QY 1420
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVV---HRNEELSEILAKKDQELEQ---QDKNSRGQAR 589
+Y L++ L+ +L D+V +L L KK ++ +Q ++KN +
Sbjct: 1421 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1480
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ R E + KET+ AL++ LE + + + NK + A E+++L ++ ++
Sbjct: 1481 DERDRAEA--EAREKETKALSLARALEEALEAKEEL-ERTNKMLKA---EMEDLVSSKDD 1534
Query: 650 KQQQIHRLEKIVLAL 664
+ +H LEK AL
Sbjct: 1535 VGKNVHELEKSKRAL 1549
Score = 74.9 bits (176), Expect = 9e-13
Identities = 113/542 (20%), Positives = 222/542 (40%), Gaps = 47/542 (8%)
Query: 162 DQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL 221
++ ++ + + + ++ + G L E + +A V LS + + L
Sbjct: 1284 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1343
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTE 280
+ KLRQ E RN + D++ E +N + + + +L + + + E
Sbjct: 1344 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1403
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE----------DQSRQKEVQLEARAR 330
++ + + + +Q E A+ L T L+ D RQ LE + R
Sbjct: 1404 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQR 1463
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K + L + +S+ +RD +AE E + + L + A+ + +E+L++T + L+
Sbjct: 1464 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLK 1522
Query: 391 EQCE--------ITKREIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD---- 435
+ E + K EL K ET++++ + +EEL+ ++ E +K +
Sbjct: 1523 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1582
Query: 436 -LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKE 489
L + E DL A + +E R + ++ + E E E K ++KL +L + E
Sbjct: 1583 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1642
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQE 548
E IK ++ + ++ +++ + D +A + A +E N + L+ +
Sbjct: 1643 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEAD 1700
Query: 549 IMDLKMKLLDVVH-------RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINV 600
+M L+ L EEL+E LA QD+ R +AR+ ++ EEL
Sbjct: 1701 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1760
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEK 659
N E R A QQ + + E + A K + Q+L + + ++H +E
Sbjct: 1761 QGNMEAMSDRVRKATQQAEQLSNELATE--RSTAQKNESARQQLERQNKELRSKLHEMEG 1818
Query: 660 IV 661
V
Sbjct: 1819 AV 1820
Score = 70.5 bits (165), Expect = 2e-11
Identities = 91/403 (22%), Positives = 178/403 (44%), Gaps = 41/403 (10%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ----------SRQKE 322
+E++ E +L++T+ R K + +L+E E + LT +L++Q + +
Sbjct: 863 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 922
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE-------VLECKQQIEKLTVQHKSAI 375
V+L A+ ++L E L E + + LQAE +L+ ++Q+E + ++A
Sbjct: 923 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAAR 978
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPD 435
Q+L+ + K T A +I K E E+ + D N + + + K++E S +
Sbjct: 979 QKLQLE-KVTAEA-----KIKKLEDEI-----LVMDDQNNKLSK-ERKLLEERISDLTTN 1026
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
L E E K ++E EV K EK + +++KL + + E I +
Sbjct: 1027 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1086
Query: 496 QIQTREL-IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
Q Q EL ++ K E+ + ++ N + +E IS DLQ+++ +
Sbjct: 1087 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS--DLQEDLDSERA 1144
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ +L E L ELE ++ Q + RE+ + VLK E++R A
Sbjct: 1145 ARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEA 1204
Query: 615 LQQDLEHR-MRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
Q++ + + V+E+ +Q+ ++ + A L+ +Q + +
Sbjct: 1205 QVQEMRQKHAQAVEELTEQL----EQFKRAKANLDKNKQTLEK 1243
Score = 52.0 bits (119), Expect = 7e-06
Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 16/208 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELD---EERTAKLAIKEKLTTTESQLRQ 285
++ +E R ++E EL E N +A+ + + E+ + +LA + RQ
Sbjct: 1743 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1800
Query: 286 TRNRVAK-MDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R K + +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 1801 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 1855
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 1856 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1912
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSK 431
+ + EL ++ + E + ++ L KSK
Sbjct: 1913 RKLQRELDEATESNEAMGREVNAL-KSK 1939
Score = 48.8 bits (111), Expect = 6e-05
Identities = 44/204 (21%), Positives = 96/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 1685 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 1739
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 1740 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 1795
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 1796 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1855
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 1856 LKQKDKKLKEILLQVEDERKMAEQ 1879
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/311 (24%), Positives = 144/311 (46%), Gaps = 33/311 (10%)
Query: 370 QHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE----LQDSRNAIEE------ 419
+ + +Q E++L++TK Q++ E +E+E K TE LQ+ A E
Sbjct: 861 RQEEEMQAKEDELQKTKER-QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 919
Query: 420 -----LQAKIIELEKSKPNPDLPTEREIDLWAELQA-TKETLRVTEDEVTTCKREKESEN 473
L AK ELE+ + E E D +LQA K+ + D + E+ +
Sbjct: 920 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 979
Query: 474 KIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNIKLNEQKV-------IQYEQYVRDL-Q 524
K+ +++ A A++ E+ I M Q +L K KL E+++ + E+ ++L +
Sbjct: 980 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1039
Query: 525 AHNRTIANCQESPNGISYQD-LQQEIMDLKMKLL-DVVHRNEELSEILAK-KDQELEQQD 581
N+ + E + ++ +QE+ LK KL D +E+++++ A+ + +++
Sbjct: 1040 LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1099
Query: 582 KNSRGQARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
K QA + ++ +E+ N LK K E ++ LQ+DL+ ++ KQ +
Sbjct: 1100 KEEELQAALARLDDEIAQKNNALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1158
Query: 639 EIQELFATLEN 649
E++ L LE+
Sbjct: 1159 ELEALKTELED 1169
Score = 31.9 bits (69), Expect = 7.9
Identities = 19/88 (21%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Query: 570 LAKKDQELE-QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI--- 625
+ ++++E++ ++D+ + + R K EL L+ K ++ + E LQ+ L+ +
Sbjct: 859 VTRQEEEMQAKEDELQKTKERQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAE 917
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQ 653
+E+ ++AAK E++E+ +E + ++
Sbjct: 918 AEEMRVRLAAKKQELEEILHEMEARLEE 945
>AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein
protein.
Length = 1177
Score = 90.6 bits (215), Expect = 2e-17
Identities = 109/512 (21%), Positives = 242/512 (47%), Gaps = 47/512 (9%)
Query: 171 HLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ 230
H+ + Q ++ ++L+ + E+ + +T SK +R+ L+ + + ++ Q
Sbjct: 257 HIEQLGLQSQKVQDLTQKLREE-EEKLKAITSKSKE---DRQKLLKLEVDFEHKASRFSQ 312
Query: 231 DVETRNVMIDEIRELRSESENTK--ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
+ E N + +E + K L + EL+E I + L E +L++ R+
Sbjct: 313 EHEEMNAKLAN-QESHNRQLRLKLVGLTQRIEELEE-------INKNLQKAEEELQELRD 364
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLI 347
++AK + A + +L V LE + + +E+ + E++ R+LR+ L+ E + +L
Sbjct: 365 KIAKGECGNSSLMAEVENLRKRV--LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELR 422
Query: 348 QQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEITK---REIE 401
+ + LQ + E +++E+ + KS QL +L++ K + L + E+ K +E+E
Sbjct: 423 LEVEKLQKRMSEL-EKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELE 481
Query: 402 LKE----RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
E + E L+D ++ +++ K+ ER++D + +V
Sbjct: 482 CSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD------GLNKNFKV 535
Query: 458 TEDEV--TTCKREKESENKIGIQQKLAAELLN----KEEIIGKMQIQ---TRELIKNIKL 508
+ +V T K +ES+ + ++ ++ ++ N ++E+IGK++ + + EL ++ L
Sbjct: 536 EQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDL 595
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
++++ E+ R++ + P ++L EI LK +L + +L +
Sbjct: 596 LKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMK 655
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELIN--VLKNKETEQSRELAALQQDLEHRMRIV 626
+ DQ LEQ+ + + +A + + E I + KNK E+ E+ + + +L HR R+
Sbjct: 656 TEDEYDQ-LEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKG-EVVSQEAELRHRFRLE 713
Query: 627 DEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ ++ + A+ ++E L NK+ Q+ +L+
Sbjct: 714 EAKSRDLKAEVQALKEKIHELMNKEDQLSQLQ 745
Score = 67.7 bits (158), Expect = 1e-10
Identities = 77/413 (18%), Positives = 187/413 (45%), Gaps = 22/413 (5%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E + ER KL +EK + ++ R+ K+ +L + ++ L +M +Q
Sbjct: 205 EQERERLKKLLEQEKAYQARKE-KENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGL 263
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+ +++ +KLRE + + TS+ + R L ++ + + + + +H+ +L
Sbjct: 264 QSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN 323
Query: 381 DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
++ + +T+R IE E LQ + ++EL+ KI + E + E
Sbjct: 324 QESHNRQLRLKLVGLTQR-IEELEEINKNLQKAEEELQELRDKIAKGECGNSSLMAEVEN 382
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKREKESEN------KIGIQ--QKLAAELLNKEEII 492
E++ E + TE + +++ + E ++ ++ QK +EL EE
Sbjct: 383 LRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAF 442
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI--ANCQESPNGISYQDLQQEIM 550
K + + +L ++ L ++K + + + +L+ + C ES + L+ ++
Sbjct: 443 SKSKSECTQL--HLNLEKEKNLT-KDLLNELEVVKSRVKELECSESRLEKAELSLKDDLT 499
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR-GQARVIKIREELIN------VLKN 603
LK + +V + + E + +++++++ +KN + Q +V+ + E+LI LK+
Sbjct: 500 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 559
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ E+ L + +L +++ +E + +++ D +++ +E +++I R
Sbjct: 560 EMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITR 612
Score = 54.0 bits (124), Expect = 2e-06
Identities = 76/436 (17%), Positives = 188/436 (43%), Gaps = 28/436 (6%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
+++L E L++ ++ + +++ R D I L++E + LE + E+ ++
Sbjct: 70 KKSLELSKEDLIQLLSIMEGELQARE---DVIHMLKTEKTKPEVLEAHYGSAEPEKVLRV 126
Query: 271 AIKEKLTTTESQLRQT--RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ + E + + ++++D+ + + + + + + E R+ +LE
Sbjct: 127 LHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE 186
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
K + + + T+ L Q+R+ L+ + + K + ++ + +L ++L + K
Sbjct: 187 KHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSF 246
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAE 447
+ + IE ++QD + E + K+ + KSK + + E+D E
Sbjct: 247 ALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDF--E 304
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK 507
+A++ +E+ +ES N+ +L +L+ + I +++ E+ KN++
Sbjct: 305 HKASR--FSQEHEEMNAKLANQESHNR-----QLRLKLVGLTQRIEELE----EINKNLQ 353
Query: 508 LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS 567
E+++ Q +RD A C S ++L++ +++++ K ++ +
Sbjct: 354 KAEEEL----QELRDKIAK----GECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCR 405
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
E L KK QE E K R + ++ R + L+ ++ E L +LE +
Sbjct: 406 E-LRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 628 EVNKQIAAKADEIQEL 643
++ ++ ++EL
Sbjct: 465 DLLNELEVVKSRVKEL 480
Score = 46.4 bits (105), Expect = 3e-04
Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 16/275 (5%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
SR L L +LK+ V+ ++ ++ E R + + + E K+ DV
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-MDV 543
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
T ++ + + L+ +SE + + + E DE KL +E+ + S+L + + + K
Sbjct: 544 -TEKLIEESKKLLKLKSEMEEKVYNLTRERDE-LIGKLKSEEEKS---SELSCSVDLLKK 598
Query: 293 MDKQLREAEASIT---SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
+ E E IT S G+ + ++ KE+ LE +L++ L+ EV L++
Sbjct: 599 RLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIE--RLKKRLQQLEVVEGDLMKT 656
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEITKREIELKERTET 408
D + + LE K + E+ S QQLEE Q K E+ E+ +E EL+ R
Sbjct: 657 ED--EYDQLEQKFRTEQDKANFLS--QQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRL 712
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
E SR+ E+QA ++ + D ++ ++D
Sbjct: 713 EEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVD 747
Score = 39.9 bits (89), Expect = 0.030
Identities = 60/306 (19%), Positives = 141/306 (46%), Gaps = 24/306 (7%)
Query: 237 VMIDEIRELR-SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
V+ ++EL SES KA ++ +L + ++ + + ++ +++Q +V ++K
Sbjct: 472 VVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNK 531
Query: 296 QLREAEASITSLTGTV-----KMLEDQSRQKE--VQLEARARKLRESLKTGEVTTSQLIQ 348
+ + + +T + K+L+ +S +E L +L LK+ E +S+L
Sbjct: 532 NFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSC 591
Query: 349 QRDSLQAE---VLECKQQIEK--------LTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
D L+ + E +++I + LT + I++L ++++ K+ LQ Q E+ +
Sbjct: 592 SVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVE 650
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +K E + + + E+ +A + + + + + I+ E+ + + LR
Sbjct: 651 GDL-MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEK-GEVVSQEAELRH 708
Query: 458 TEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
R+ ++E + +++K+ EL+NKE+ + ++Q+ L + E K
Sbjct: 709 RFRLEEAKSRDLKAEVQ-ALKEKIH-ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMG 766
Query: 518 QYVRDL 523
Q V +L
Sbjct: 767 QEVLNL 772
>AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 89.0 bits (211), Expect = 5e-17
Identities = 107/510 (20%), Positives = 240/510 (47%), Gaps = 43/510 (8%)
Query: 171 HLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ 230
H+ + Q ++ ++L+ + E+ + +T SK +R+ L+ + + ++ Q
Sbjct: 257 HIEQLGLQSQKVQDLTQKLREE-EEKLKAITSKSKE---DRQKLLKLEVDFEHKASRFSQ 312
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
+ E N + +E + K + + + E T K L E +L++ R+++
Sbjct: 313 EHEEMNAKLAN-QESHNRQLRLKLVGLTQRIEELEETNK-----NLQKAEEELQELRDKI 366
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQ 349
AK + A + +L V LE + + +E+ + E++ R+LR+ L+ E + +L +
Sbjct: 367 AKGECGNSSLMAEVENLRKRV--LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 424
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEITK---REIELK 403
+ LQ + E +++E+ + KS QL +L++ K + L + E+ K +E+E
Sbjct: 425 VEKLQKRMSEL-EKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 483
Query: 404 E----RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E + E L+D ++ +++ K+ ER++D + +V +
Sbjct: 484 ESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD------GLNKNFKVEQ 537
Query: 460 DEV--TTCKREKESENKIGIQQKLAAELLN----KEEIIGKMQIQ---TRELIKNIKLNE 510
+V T K +ES+ + ++ ++ ++ N ++E+IGK++ + + EL ++ L +
Sbjct: 538 GKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLK 597
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+++ E+ R++ + P ++L EI LK +L + +L +
Sbjct: 598 KRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTE 657
Query: 571 AKKDQELEQQDKNSRGQARVIKIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDE 628
+ DQ LEQ+ + + +A + + E I + KNK E+ E+ + + +L HR R+ +
Sbjct: 658 DEYDQ-LEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKG-EVVSQEAELRHRFRLEEA 715
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ + A+ ++E L NK+ Q+ +L+
Sbjct: 716 KSRDLKAEVQALKEKIHELMNKEDQLSQLQ 745
Score = 75.8 bits (178), Expect = 5e-13
Identities = 102/435 (23%), Positives = 205/435 (47%), Gaps = 34/435 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIK-EKLTTTESQLRQTRN-RVAKMDKQL 297
D ++LR E E KA+ E D ++ KL + E + SQ + N ++A +
Sbjct: 270 DLTQKLREEEEKLKAITSKSKE-DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHN 328
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
R+ + LT ++ LE+ ++ + + E ++LR+ + GE S L+ + ++L+ V
Sbjct: 329 RQLRLKLVGLTQRIEELEETNKNLQ-KAEEELQELRDKIAKGECGNSSLMAEVENLRKRV 387
Query: 358 LECK---QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
LE + ++I K Q + ++L+E+ +K E ++ KR EL E+ E S+
Sbjct: 388 LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSEL-EKLEEAFSKSK 446
Query: 415 NAIEELQAKIIELEKSKP-NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE-KESE 472
+ +L + LEK K DL E E+ +++ + L +E + + K+
Sbjct: 447 SECTQLH---LNLEKEKNLTKDLLNELEV-----VKSRVKELECSESRLEKAELSLKDDL 498
Query: 473 NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTI 530
K+ L E N E I + + + L KN K+ + KV+ E+ + + + +
Sbjct: 499 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLK 558
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKN-SRG 586
+ +E +L +E +L KL ++ ELS ++L K+ +E+ ++ +RG
Sbjct: 559 SEMEE-----KVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRG 613
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++R EL NK E + E+ L++ L+ ++ +V+ + + D++++ F T
Sbjct: 614 RSRK---GSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVEGDLMKTEDEYDQLEQKFRT 669
Query: 647 LENKQQQI-HRLEKI 660
++K + +LE+I
Sbjct: 670 EQDKANFLSQQLEEI 684
Score = 70.1 bits (164), Expect = 2e-11
Identities = 78/413 (18%), Positives = 188/413 (45%), Gaps = 22/413 (5%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E + ER KL +EK + ++ R+ K+ +L + ++ L +M +Q
Sbjct: 205 EQERERLKKLLEQEKAYQARKE-KENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGL 263
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+ +++ +KLRE + + TS+ + R L ++ + + + + +H+ +L
Sbjct: 264 QSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN 323
Query: 381 DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
++ + +T+R IE E T LQ + ++EL+ KI + E + E
Sbjct: 324 QESHNRQLRLKLVGLTQR-IEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVEN 382
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKREKESEN------KIGIQ--QKLAAELLNKEEII 492
E++ E + TE + +++ + E ++ ++ QK +EL EE
Sbjct: 383 LRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAF 442
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI--ANCQESPNGISYQDLQQEIM 550
K + + +L ++ L ++K + + + +L+ + C ES + L+ ++
Sbjct: 443 SKSKSECTQL--HLNLEKEKNLT-KDLLNELEVVKSRVKELECSESRLEKAELSLKDDLT 499
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR-GQARVIKIREELIN------VLKN 603
LK + +V + + E + +++++++ +KN + Q +V+ + E+LI LK+
Sbjct: 500 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 559
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ E+ L + +L +++ +E + +++ D +++ +E +++I R
Sbjct: 560 EMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITR 612
Score = 52.8 bits (121), Expect = 4e-06
Identities = 76/436 (17%), Positives = 187/436 (42%), Gaps = 28/436 (6%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
+++L E L++ ++ + +++ R D I L++E + LE + E+ ++
Sbjct: 70 KKSLELSKEDLIQLLSIMEGELQARE---DVIHMLKTEKTKPEVLEAHYGSAEPEKVLRV 126
Query: 271 AIKEKLTTTESQLRQT--RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ + E + + ++++D+ + + + + + + E R+ +LE
Sbjct: 127 LHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE 186
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
K + + + T+ L Q+R+ L+ + + K + ++ + +L ++L + K
Sbjct: 187 KHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSF 246
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAE 447
+ + IE ++QD + E + K+ + KSK + + E+D E
Sbjct: 247 ALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDF--E 304
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK 507
+A++ +E+ +ES N+ +L +L+ + I +++ E KN++
Sbjct: 305 HKASR--FSQEHEEMNAKLANQESHNR-----QLRLKLVGLTQRIEELE----ETNKNLQ 353
Query: 508 LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS 567
E+++ Q +RD A C S ++L++ +++++ K ++ +
Sbjct: 354 KAEEEL----QELRDKIAK----GECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCR 405
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
E L KK QE E K R + ++ R + L+ ++ E L +LE +
Sbjct: 406 E-LRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 628 EVNKQIAAKADEIQEL 643
++ ++ ++EL
Sbjct: 465 DLLNELEVVKSRVKEL 480
Score = 46.4 bits (105), Expect = 3e-04
Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 16/275 (5%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
SR L L +LK+ V+ ++ ++ E R + + + E K+ DV
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-MDV 543
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
T ++ + + L+ +SE + + + E DE KL +E+ + S+L + + + K
Sbjct: 544 -TEKLIEESKKLLKLKSEMEEKVYNLTRERDE-LIGKLKSEEEKS---SELSCSVDLLKK 598
Query: 293 MDKQLREAEASIT---SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
+ E E IT S G+ + ++ KE+ LE +L++ L+ EV L++
Sbjct: 599 RLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIE--RLKKRLQQLEVVEGDLMKT 656
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEITKREIELKERTET 408
D + + LE K + E+ S QQLEE Q K E+ E+ +E EL+ R
Sbjct: 657 ED--EYDQLEQKFRTEQDKANFLS--QQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRL 712
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
E SR+ E+QA ++ + D ++ ++D
Sbjct: 713 EEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVD 747
Score = 39.9 bits (89), Expect = 0.030
Identities = 60/306 (19%), Positives = 141/306 (46%), Gaps = 24/306 (7%)
Query: 237 VMIDEIRELR-SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
V+ ++EL SES KA ++ +L + ++ + + ++ +++Q +V ++K
Sbjct: 472 VVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNK 531
Query: 296 QLREAEASITSLTGTV-----KMLEDQSRQKE--VQLEARARKLRESLKTGEVTTSQLIQ 348
+ + + +T + K+L+ +S +E L +L LK+ E +S+L
Sbjct: 532 NFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSC 591
Query: 349 QRDSLQAE---VLECKQQIEK--------LTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
D L+ + E +++I + LT + I++L ++++ K+ LQ Q E+ +
Sbjct: 592 SVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVE 650
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +K E + + + E+ +A + + + + + I+ E+ + + LR
Sbjct: 651 GDL-MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEK-GEVVSQEAELRH 708
Query: 458 TEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
R+ ++E + +++K+ EL+NKE+ + ++Q+ L + E K
Sbjct: 709 RFRLEEAKSRDLKAEVQ-ALKEKIH-ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMG 766
Query: 518 QYVRDL 523
Q V +L
Sbjct: 767 QEVLNL 772
>AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 89.0 bits (211), Expect = 5e-17
Identities = 107/510 (20%), Positives = 240/510 (47%), Gaps = 43/510 (8%)
Query: 171 HLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ 230
H+ + Q ++ ++L+ + E+ + +T SK +R+ L+ + + ++ Q
Sbjct: 158 HIEQLGLQSQKVQDLTQKLREE-EEKLKAITSKSKE---DRQKLLKLEVDFEHKASRFSQ 213
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
+ E N + +E + K + + + E T K L E +L++ R+++
Sbjct: 214 EHEEMNAKLAN-QESHNRQLRLKLVGLTQRIEELEETNK-----NLQKAEEELQELRDKI 267
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQ 349
AK + A + +L V LE + + +E+ + E++ R+LR+ L+ E + +L +
Sbjct: 268 AKGECGNSSLMAEVENLRKRV--LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 325
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEITK---REIELK 403
+ LQ + E +++E+ + KS QL +L++ K + L + E+ K +E+E
Sbjct: 326 VEKLQKRMSEL-EKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 384
Query: 404 E----RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E + E L+D ++ +++ K+ ER++D + +V +
Sbjct: 385 ESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD------GLNKNFKVEQ 438
Query: 460 DEV--TTCKREKESENKIGIQQKLAAELLN----KEEIIGKMQIQ---TRELIKNIKLNE 510
+V T K +ES+ + ++ ++ ++ N ++E+IGK++ + + EL ++ L +
Sbjct: 439 GKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLK 498
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+++ E+ R++ + P ++L EI LK +L + +L +
Sbjct: 499 KRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTE 558
Query: 571 AKKDQELEQQDKNSRGQARVIKIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDE 628
+ DQ LEQ+ + + +A + + E I + KNK E+ E+ + + +L HR R+ +
Sbjct: 559 DEYDQ-LEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKG-EVVSQEAELRHRFRLEEA 616
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ + A+ ++E L NK+ Q+ +L+
Sbjct: 617 KSRDLKAEVQALKEKIHELMNKEDQLSQLQ 646
Score = 75.8 bits (178), Expect = 5e-13
Identities = 102/435 (23%), Positives = 205/435 (47%), Gaps = 34/435 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIK-EKLTTTESQLRQTRN-RVAKMDKQL 297
D ++LR E E KA+ E D ++ KL + E + SQ + N ++A +
Sbjct: 171 DLTQKLREEEEKLKAITSKSKE-DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHN 229
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
R+ + LT ++ LE+ ++ + + E ++LR+ + GE S L+ + ++L+ V
Sbjct: 230 RQLRLKLVGLTQRIEELEETNKNLQ-KAEEELQELRDKIAKGECGNSSLMAEVENLRKRV 288
Query: 358 LECK---QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
LE + ++I K Q + ++L+E+ +K E ++ KR EL E+ E S+
Sbjct: 289 LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSEL-EKLEEAFSKSK 347
Query: 415 NAIEELQAKIIELEKSKP-NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE-KESE 472
+ +L + LEK K DL E E+ +++ + L +E + + K+
Sbjct: 348 SECTQLH---LNLEKEKNLTKDLLNELEV-----VKSRVKELECSESRLEKAELSLKDDL 399
Query: 473 NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTI 530
K+ L E N E I + + + L KN K+ + KV+ E+ + + + +
Sbjct: 400 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLK 459
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKN-SRG 586
+ +E +L +E +L KL ++ ELS ++L K+ +E+ ++ +RG
Sbjct: 460 SEMEE-----KVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRG 514
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++R EL NK E + E+ L++ L+ ++ +V+ + + D++++ F T
Sbjct: 515 RSRK---GSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVEGDLMKTEDEYDQLEQKFRT 570
Query: 647 LENKQQQI-HRLEKI 660
++K + +LE+I
Sbjct: 571 EQDKANFLSQQLEEI 585
Score = 70.1 bits (164), Expect = 2e-11
Identities = 78/413 (18%), Positives = 188/413 (45%), Gaps = 22/413 (5%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E + ER KL +EK + ++ R+ K+ +L + ++ L +M +Q
Sbjct: 106 EQERERLKKLLEQEKAYQARKE-KENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGL 164
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+ +++ +KLRE + + TS+ + R L ++ + + + + +H+ +L
Sbjct: 165 QSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN 224
Query: 381 DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
++ + +T+R IE E T LQ + ++EL+ KI + E + E
Sbjct: 225 QESHNRQLRLKLVGLTQR-IEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVEN 283
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKREKESEN------KIGIQ--QKLAAELLNKEEII 492
E++ E + TE + +++ + E ++ ++ QK +EL EE
Sbjct: 284 LRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAF 343
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI--ANCQESPNGISYQDLQQEIM 550
K + + +L ++ L ++K + + + +L+ + C ES + L+ ++
Sbjct: 344 SKSKSECTQL--HLNLEKEKNLT-KDLLNELEVVKSRVKELECSESRLEKAELSLKDDLT 400
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR-GQARVIKIREELIN------VLKN 603
LK + +V + + E + +++++++ +KN + Q +V+ + E+LI LK+
Sbjct: 401 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 460
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ E+ L + +L +++ +E + +++ D +++ +E +++I R
Sbjct: 461 EMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITR 513
Score = 49.2 bits (112), Expect = 5e-05
Identities = 70/402 (17%), Positives = 170/402 (42%), Gaps = 25/402 (6%)
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAEA 302
L++E + LE + E+ ++ ++ + E + + ++++D+ + +
Sbjct: 2 LKTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKE 61
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
+ + + + E R+ +LE K + + + T+ L Q+R+ L+ + + K
Sbjct: 62 TYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKA 121
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
+ ++ + +L ++L + K + + IE ++QD + E +
Sbjct: 122 YQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEE 181
Query: 423 KIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ + KSK + + E+D E +A++ +E+ +ES N+ +L
Sbjct: 182 KLKAITSKSKEDRQKLLKLEVDF--EHKASR--FSQEHEEMNAKLANQESHNR-----QL 232
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
+L+ + I +++ E KN++ E+++ Q +RD A C S
Sbjct: 233 RLKLVGLTQRIEELE----ETNKNLQKAEEEL----QELRDKIAK----GECGNSSLMAE 280
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVL 601
++L++ +++++ K ++ + E L KK QE E K R + ++ R + L
Sbjct: 281 VENLRKRVLEMEGKDEEITKTESQCRE-LRKKLQEEEHHSKELRLEVEKLQKRMSELEKL 339
Query: 602 KNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
+ ++ E L +LE + ++ ++ ++EL
Sbjct: 340 EEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKEL 381
Score = 46.4 bits (105), Expect = 3e-04
Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 16/275 (5%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
SR L L +LK+ V+ ++ ++ E R + + + E K+ DV
Sbjct: 386 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-MDV 444
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
T ++ + + L+ +SE + + + E DE KL +E+ + S+L + + + K
Sbjct: 445 -TEKLIEESKKLLKLKSEMEEKVYNLTRERDE-LIGKLKSEEEKS---SELSCSVDLLKK 499
Query: 293 MDKQLREAEASIT---SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
+ E E IT S G+ + ++ KE+ LE +L++ L+ EV L++
Sbjct: 500 RLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIE--RLKKRLQQLEVVEGDLMKT 557
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEITKREIELKERTET 408
D + + LE K + E+ S QQLEE Q K E+ E+ +E EL+ R
Sbjct: 558 ED--EYDQLEQKFRTEQDKANFLS--QQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRL 613
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
E SR+ E+QA ++ + D ++ ++D
Sbjct: 614 EEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVD 648
Score = 39.9 bits (89), Expect = 0.030
Identities = 60/306 (19%), Positives = 141/306 (46%), Gaps = 24/306 (7%)
Query: 237 VMIDEIRELR-SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
V+ ++EL SES KA ++ +L + ++ + + ++ +++Q +V ++K
Sbjct: 373 VVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNK 432
Query: 296 QLREAEASITSLTGTV-----KMLEDQSRQKE--VQLEARARKLRESLKTGEVTTSQLIQ 348
+ + + +T + K+L+ +S +E L +L LK+ E +S+L
Sbjct: 433 NFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSC 492
Query: 349 QRDSLQAE---VLECKQQIEK--------LTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
D L+ + E +++I + LT + I++L ++++ K+ LQ Q E+ +
Sbjct: 493 SVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVE 551
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +K E + + + E+ +A + + + + + I+ E+ + + LR
Sbjct: 552 GDL-MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEK-GEVVSQEAELRH 609
Query: 458 TEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
R+ ++E + +++K+ EL+NKE+ + ++Q+ L + E K
Sbjct: 610 RFRLEEAKSRDLKAEVQ-ALKEKIH-ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMG 667
Query: 518 QYVRDL 523
Q V +L
Sbjct: 668 QEVLNL 673
>AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 89.0 bits (211), Expect = 5e-17
Identities = 107/510 (20%), Positives = 240/510 (47%), Gaps = 43/510 (8%)
Query: 171 HLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ 230
H+ + Q ++ ++L+ + E+ + +T SK +R+ L+ + + ++ Q
Sbjct: 257 HIEQLGLQSQKVQDLTQKLREE-EEKLKAITSKSKE---DRQKLLKLEVDFEHKASRFSQ 312
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
+ E N + +E + K + + + E T K L E +L++ R+++
Sbjct: 313 EHEEMNAKLAN-QESHNRQLRLKLVGLTQRIEELEETNK-----NLQKAEEELQELRDKI 366
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQ 349
AK + A + +L V LE + + +E+ + E++ R+LR+ L+ E + +L +
Sbjct: 367 AKGECGNSSLMAEVENLRKRV--LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 424
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEITK---REIELK 403
+ LQ + E +++E+ + KS QL +L++ K + L + E+ K +E+E
Sbjct: 425 VEKLQKRMSEL-EKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 483
Query: 404 E----RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E + E L+D ++ +++ K+ ER++D + +V +
Sbjct: 484 ESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD------GLNKNFKVEQ 537
Query: 460 DEV--TTCKREKESENKIGIQQKLAAELLN----KEEIIGKMQIQ---TRELIKNIKLNE 510
+V T K +ES+ + ++ ++ ++ N ++E+IGK++ + + EL ++ L +
Sbjct: 538 GKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLK 597
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+++ E+ R++ + P ++L EI LK +L + +L +
Sbjct: 598 KRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTE 657
Query: 571 AKKDQELEQQDKNSRGQARVIKIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDE 628
+ DQ LEQ+ + + +A + + E I + KNK E+ E+ + + +L HR R+ +
Sbjct: 658 DEYDQ-LEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKG-EVVSQEAELRHRFRLEEA 715
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ + A+ ++E L NK+ Q+ +L+
Sbjct: 716 KSRDLKAEVQALKEKIHELMNKEDQLSQLQ 745
Score = 75.8 bits (178), Expect = 5e-13
Identities = 102/435 (23%), Positives = 205/435 (47%), Gaps = 34/435 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIK-EKLTTTESQLRQTRN-RVAKMDKQL 297
D ++LR E E KA+ E D ++ KL + E + SQ + N ++A +
Sbjct: 270 DLTQKLREEEEKLKAITSKSKE-DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHN 328
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
R+ + LT ++ LE+ ++ + + E ++LR+ + GE S L+ + ++L+ V
Sbjct: 329 RQLRLKLVGLTQRIEELEETNKNLQ-KAEEELQELRDKIAKGECGNSSLMAEVENLRKRV 387
Query: 358 LECK---QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
LE + ++I K Q + ++L+E+ +K E ++ KR EL E+ E S+
Sbjct: 388 LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSEL-EKLEEAFSKSK 446
Query: 415 NAIEELQAKIIELEKSKP-NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE-KESE 472
+ +L + LEK K DL E E+ +++ + L +E + + K+
Sbjct: 447 SECTQLH---LNLEKEKNLTKDLLNELEV-----VKSRVKELECSESRLEKAELSLKDDL 498
Query: 473 NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTI 530
K+ L E N E I + + + L KN K+ + KV+ E+ + + + +
Sbjct: 499 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLK 558
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKN-SRG 586
+ +E +L +E +L KL ++ ELS ++L K+ +E+ ++ +RG
Sbjct: 559 SEMEE-----KVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRG 613
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++R EL NK E + E+ L++ L+ ++ +V+ + + D++++ F T
Sbjct: 614 RSRK---GSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVEGDLMKTEDEYDQLEQKFRT 669
Query: 647 LENKQQQI-HRLEKI 660
++K + +LE+I
Sbjct: 670 EQDKANFLSQQLEEI 684
Score = 70.1 bits (164), Expect = 2e-11
Identities = 78/413 (18%), Positives = 188/413 (45%), Gaps = 22/413 (5%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E + ER KL +EK + ++ R+ K+ +L + ++ L +M +Q
Sbjct: 205 EQERERLKKLLEQEKAYQARKE-KENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGL 263
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+ +++ +KLRE + + TS+ + R L ++ + + + + +H+ +L
Sbjct: 264 QSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN 323
Query: 381 DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
++ + +T+R IE E T LQ + ++EL+ KI + E + E
Sbjct: 324 QESHNRQLRLKLVGLTQR-IEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVEN 382
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKREKESEN------KIGIQ--QKLAAELLNKEEII 492
E++ E + TE + +++ + E ++ ++ QK +EL EE
Sbjct: 383 LRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAF 442
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI--ANCQESPNGISYQDLQQEIM 550
K + + +L ++ L ++K + + + +L+ + C ES + L+ ++
Sbjct: 443 SKSKSECTQL--HLNLEKEKNLT-KDLLNELEVVKSRVKELECSESRLEKAELSLKDDLT 499
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR-GQARVIKIREELIN------VLKN 603
LK + +V + + E + +++++++ +KN + Q +V+ + E+LI LK+
Sbjct: 500 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 559
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ E+ L + +L +++ +E + +++ D +++ +E +++I R
Sbjct: 560 EMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITR 612
Score = 52.8 bits (121), Expect = 4e-06
Identities = 76/436 (17%), Positives = 187/436 (42%), Gaps = 28/436 (6%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
+++L E L++ ++ + +++ R D I L++E + LE + E+ ++
Sbjct: 70 KKSLELSKEDLIQLLSIMEGELQARE---DVIHMLKTEKTKPEVLEAHYGSAEPEKVLRV 126
Query: 271 AIKEKLTTTESQLRQT--RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ + E + + ++++D+ + + + + + + E R+ +LE
Sbjct: 127 LHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE 186
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
K + + + T+ L Q+R+ L+ + + K + ++ + +L ++L + K
Sbjct: 187 KHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSF 246
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAE 447
+ + IE ++QD + E + K+ + KSK + + E+D E
Sbjct: 247 ALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDF--E 304
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK 507
+A++ +E+ +ES N+ +L +L+ + I +++ E KN++
Sbjct: 305 HKASR--FSQEHEEMNAKLANQESHNR-----QLRLKLVGLTQRIEELE----ETNKNLQ 353
Query: 508 LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS 567
E+++ Q +RD A C S ++L++ +++++ K ++ +
Sbjct: 354 KAEEEL----QELRDKIAK----GECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCR 405
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
E L KK QE E K R + ++ R + L+ ++ E L +LE +
Sbjct: 406 E-LRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 628 EVNKQIAAKADEIQEL 643
++ ++ ++EL
Sbjct: 465 DLLNELEVVKSRVKEL 480
Score = 46.4 bits (105), Expect = 3e-04
Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 16/275 (5%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
SR L L +LK+ V+ ++ ++ E R + + + E K+ DV
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-MDV 543
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
T ++ + + L+ +SE + + + E DE KL +E+ + S+L + + + K
Sbjct: 544 -TEKLIEESKKLLKLKSEMEEKVYNLTRERDE-LIGKLKSEEEKS---SELSCSVDLLKK 598
Query: 293 MDKQLREAEASIT---SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
+ E E IT S G+ + ++ KE+ LE +L++ L+ EV L++
Sbjct: 599 RLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIE--RLKKRLQQLEVVEGDLMKT 656
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEITKREIELKERTET 408
D + + LE K + E+ S QQLEE Q K E+ E+ +E EL+ R
Sbjct: 657 ED--EYDQLEQKFRTEQDKANFLS--QQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRL 712
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
E SR+ E+QA ++ + D ++ ++D
Sbjct: 713 EEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVD 747
Score = 39.9 bits (89), Expect = 0.030
Identities = 60/306 (19%), Positives = 141/306 (46%), Gaps = 24/306 (7%)
Query: 237 VMIDEIRELR-SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
V+ ++EL SES KA ++ +L + ++ + + ++ +++Q +V ++K
Sbjct: 472 VVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNK 531
Query: 296 QLREAEASITSLTGTV-----KMLEDQSRQKE--VQLEARARKLRESLKTGEVTTSQLIQ 348
+ + + +T + K+L+ +S +E L +L LK+ E +S+L
Sbjct: 532 NFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSC 591
Query: 349 QRDSLQAE---VLECKQQIEK--------LTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
D L+ + E +++I + LT + I++L ++++ K+ LQ Q E+ +
Sbjct: 592 SVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVE 650
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +K E + + + E+ +A + + + + + I+ E+ + + LR
Sbjct: 651 GDL-MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEK-GEVVSQEAELRH 708
Query: 458 TEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
R+ ++E + +++K+ EL+NKE+ + ++Q+ L + E K
Sbjct: 709 RFRLEEAKSRDLKAEVQ-ALKEKIH-ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMG 766
Query: 518 QYVRDL 523
Q V +L
Sbjct: 767 QEVLNL 772
>AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 89.0 bits (211), Expect = 5e-17
Identities = 107/510 (20%), Positives = 240/510 (47%), Gaps = 43/510 (8%)
Query: 171 HLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ 230
H+ + Q ++ ++L+ + E+ + +T SK +R+ L+ + + ++ Q
Sbjct: 158 HIEQLGLQSQKVQDLTQKLREE-EEKLKAITSKSKE---DRQKLLKLEVDFEHKASRFSQ 213
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
+ E N + +E + K + + + E T K L E +L++ R+++
Sbjct: 214 EHEEMNAKLAN-QESHNRQLRLKLVGLTQRIEELEETNK-----NLQKAEEELQELRDKI 267
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQ 349
AK + A + +L V LE + + +E+ + E++ R+LR+ L+ E + +L +
Sbjct: 268 AKGECGNSSLMAEVENLRKRV--LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 325
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEITK---REIELK 403
+ LQ + E +++E+ + KS QL +L++ K + L + E+ K +E+E
Sbjct: 326 VEKLQKRMSEL-EKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 384
Query: 404 E----RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E + E L+D ++ +++ K+ ER++D + +V +
Sbjct: 385 ESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD------GLNKNFKVEQ 438
Query: 460 DEV--TTCKREKESENKIGIQQKLAAELLN----KEEIIGKMQIQ---TRELIKNIKLNE 510
+V T K +ES+ + ++ ++ ++ N ++E+IGK++ + + EL ++ L +
Sbjct: 439 GKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLK 498
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+++ E+ R++ + P ++L EI LK +L + +L +
Sbjct: 499 KRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTE 558
Query: 571 AKKDQELEQQDKNSRGQARVIKIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDE 628
+ DQ LEQ+ + + +A + + E I + KNK E+ E+ + + +L HR R+ +
Sbjct: 559 DEYDQ-LEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKG-EVVSQEAELRHRFRLEEA 616
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ + A+ ++E L NK+ Q+ +L+
Sbjct: 617 KSRDLKAEVQALKEKIHELMNKEDQLSQLQ 646
Score = 75.8 bits (178), Expect = 5e-13
Identities = 102/435 (23%), Positives = 205/435 (47%), Gaps = 34/435 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIK-EKLTTTESQLRQTRN-RVAKMDKQL 297
D ++LR E E KA+ E D ++ KL + E + SQ + N ++A +
Sbjct: 171 DLTQKLREEEEKLKAITSKSKE-DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHN 229
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
R+ + LT ++ LE+ ++ + + E ++LR+ + GE S L+ + ++L+ V
Sbjct: 230 RQLRLKLVGLTQRIEELEETNKNLQ-KAEEELQELRDKIAKGECGNSSLMAEVENLRKRV 288
Query: 358 LECK---QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
LE + ++I K Q + ++L+E+ +K E ++ KR EL E+ E S+
Sbjct: 289 LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSEL-EKLEEAFSKSK 347
Query: 415 NAIEELQAKIIELEKSKP-NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE-KESE 472
+ +L + LEK K DL E E+ +++ + L +E + + K+
Sbjct: 348 SECTQLH---LNLEKEKNLTKDLLNELEV-----VKSRVKELECSESRLEKAELSLKDDL 399
Query: 473 NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTI 530
K+ L E N E I + + + L KN K+ + KV+ E+ + + + +
Sbjct: 400 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLK 459
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKN-SRG 586
+ +E +L +E +L KL ++ ELS ++L K+ +E+ ++ +RG
Sbjct: 460 SEMEE-----KVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRG 514
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++R EL NK E + E+ L++ L+ ++ +V+ + + D++++ F T
Sbjct: 515 RSRK---GSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVEGDLMKTEDEYDQLEQKFRT 570
Query: 647 LENKQQQI-HRLEKI 660
++K + +LE+I
Sbjct: 571 EQDKANFLSQQLEEI 585
Score = 70.1 bits (164), Expect = 2e-11
Identities = 78/413 (18%), Positives = 188/413 (45%), Gaps = 22/413 (5%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E + ER KL +EK + ++ R+ K+ +L + ++ L +M +Q
Sbjct: 106 EQERERLKKLLEQEKAYQARKE-KENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGL 164
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+ +++ +KLRE + + TS+ + R L ++ + + + + +H+ +L
Sbjct: 165 QSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN 224
Query: 381 DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
++ + +T+R IE E T LQ + ++EL+ KI + E + E
Sbjct: 225 QESHNRQLRLKLVGLTQR-IEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVEN 283
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKREKESEN------KIGIQ--QKLAAELLNKEEII 492
E++ E + TE + +++ + E ++ ++ QK +EL EE
Sbjct: 284 LRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAF 343
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI--ANCQESPNGISYQDLQQEIM 550
K + + +L ++ L ++K + + + +L+ + C ES + L+ ++
Sbjct: 344 SKSKSECTQL--HLNLEKEKNLT-KDLLNELEVVKSRVKELECSESRLEKAELSLKDDLT 400
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR-GQARVIKIREELIN------VLKN 603
LK + +V + + E + +++++++ +KN + Q +V+ + E+LI LK+
Sbjct: 401 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 460
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ E+ L + +L +++ +E + +++ D +++ +E +++I R
Sbjct: 461 EMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITR 513
Score = 49.2 bits (112), Expect = 5e-05
Identities = 70/402 (17%), Positives = 170/402 (42%), Gaps = 25/402 (6%)
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAEA 302
L++E + LE + E+ ++ ++ + E + + ++++D+ + +
Sbjct: 2 LKTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKE 61
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
+ + + + E R+ +LE K + + + T+ L Q+R+ L+ + + K
Sbjct: 62 TYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKA 121
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
+ ++ + +L ++L + K + + IE ++QD + E +
Sbjct: 122 YQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEE 181
Query: 423 KIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ + KSK + + E+D E +A++ +E+ +ES N+ +L
Sbjct: 182 KLKAITSKSKEDRQKLLKLEVDF--EHKASR--FSQEHEEMNAKLANQESHNR-----QL 232
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
+L+ + I +++ E KN++ E+++ Q +RD A C S
Sbjct: 233 RLKLVGLTQRIEELE----ETNKNLQKAEEEL----QELRDKIAK----GECGNSSLMAE 280
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVL 601
++L++ +++++ K ++ + E L KK QE E K R + ++ R + L
Sbjct: 281 VENLRKRVLEMEGKDEEITKTESQCRE-LRKKLQEEEHHSKELRLEVEKLQKRMSELEKL 339
Query: 602 KNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
+ ++ E L +LE + ++ ++ ++EL
Sbjct: 340 EEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKEL 381
Score = 46.4 bits (105), Expect = 3e-04
Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 16/275 (5%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
SR L L +LK+ V+ ++ ++ E R + + + E K+ DV
Sbjct: 386 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-MDV 444
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
T ++ + + L+ +SE + + + E DE KL +E+ + S+L + + + K
Sbjct: 445 -TEKLIEESKKLLKLKSEMEEKVYNLTRERDE-LIGKLKSEEEKS---SELSCSVDLLKK 499
Query: 293 MDKQLREAEASIT---SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
+ E E IT S G+ + ++ KE+ LE +L++ L+ EV L++
Sbjct: 500 RLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIE--RLKKRLQQLEVVEGDLMKT 557
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEITKREIELKERTET 408
D + + LE K + E+ S QQLEE Q K E+ E+ +E EL+ R
Sbjct: 558 ED--EYDQLEQKFRTEQDKANFLS--QQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRL 613
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
E SR+ E+QA ++ + D ++ ++D
Sbjct: 614 EEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVD 648
Score = 39.9 bits (89), Expect = 0.030
Identities = 60/306 (19%), Positives = 141/306 (46%), Gaps = 24/306 (7%)
Query: 237 VMIDEIRELR-SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
V+ ++EL SES KA ++ +L + ++ + + ++ +++Q +V ++K
Sbjct: 373 VVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNK 432
Query: 296 QLREAEASITSLTGTV-----KMLEDQSRQKE--VQLEARARKLRESLKTGEVTTSQLIQ 348
+ + + +T + K+L+ +S +E L +L LK+ E +S+L
Sbjct: 433 NFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSC 492
Query: 349 QRDSLQAE---VLECKQQIEK--------LTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
D L+ + E +++I + LT + I++L ++++ K+ LQ Q E+ +
Sbjct: 493 SVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVE 551
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +K E + + + E+ +A + + + + + I+ E+ + + LR
Sbjct: 552 GDL-MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEK-GEVVSQEAELRH 609
Query: 458 TEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
R+ ++E + +++K+ EL+NKE+ + ++Q+ L + E K
Sbjct: 610 RFRLEEAKSRDLKAEVQ-ALKEKIH-ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMG 667
Query: 518 QYVRDL 523
Q V +L
Sbjct: 668 QEVLNL 673
>AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein.
Length = 1213
Score = 89.0 bits (211), Expect = 5e-17
Identities = 107/510 (20%), Positives = 240/510 (47%), Gaps = 43/510 (8%)
Query: 171 HLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ 230
H+ + Q ++ ++L+ + E+ + +T SK +R+ L+ + + ++ Q
Sbjct: 257 HIEQLGLQSQKVQDLTQKLREE-EEKLKAITSKSKE---DRQKLLKLEVDFEHKASRFSQ 312
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
+ E N + +E + K + + + E T K L E +L++ R+++
Sbjct: 313 EHEEMNAKLAN-QESHNRQLRLKLVGLTQRIEELEETNK-----NLQKAEEELQELRDKI 366
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQ 349
AK + A + +L V LE + + +E+ + E++ R+LR+ L+ E + +L +
Sbjct: 367 AKGECGNSSLMAEVENLRKRV--LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 424
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEITK---REIELK 403
+ LQ + E +++E+ + KS QL +L++ K + L + E+ K +E+E
Sbjct: 425 VEKLQKRMSEL-EKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 483
Query: 404 E----RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E + E L+D ++ +++ K+ ER++D + +V +
Sbjct: 484 ESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD------GLNKNFKVEQ 537
Query: 460 DEV--TTCKREKESENKIGIQQKLAAELLN----KEEIIGKMQIQ---TRELIKNIKLNE 510
+V T K +ES+ + ++ ++ ++ N ++E+IGK++ + + EL ++ L +
Sbjct: 538 GKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLK 597
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+++ E+ R++ + P ++L EI LK +L + +L +
Sbjct: 598 KRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTE 657
Query: 571 AKKDQELEQQDKNSRGQARVIKIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDE 628
+ DQ LEQ+ + + +A + + E I + KNK E+ E+ + + +L HR R+ +
Sbjct: 658 DEYDQ-LEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKG-EVVSQEAELRHRFRLEEA 715
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ + A+ ++E L NK+ Q+ +L+
Sbjct: 716 KSRDLKAEVQALKEKIHELMNKEDQLSQLQ 745
Score = 75.8 bits (178), Expect = 5e-13
Identities = 102/435 (23%), Positives = 205/435 (47%), Gaps = 34/435 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIK-EKLTTTESQLRQTRN-RVAKMDKQL 297
D ++LR E E KA+ E D ++ KL + E + SQ + N ++A +
Sbjct: 270 DLTQKLREEEEKLKAITSKSKE-DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHN 328
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
R+ + LT ++ LE+ ++ + + E ++LR+ + GE S L+ + ++L+ V
Sbjct: 329 RQLRLKLVGLTQRIEELEETNKNLQ-KAEEELQELRDKIAKGECGNSSLMAEVENLRKRV 387
Query: 358 LECK---QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
LE + ++I K Q + ++L+E+ +K E ++ KR EL E+ E S+
Sbjct: 388 LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSEL-EKLEEAFSKSK 446
Query: 415 NAIEELQAKIIELEKSKP-NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE-KESE 472
+ +L + LEK K DL E E+ +++ + L +E + + K+
Sbjct: 447 SECTQLH---LNLEKEKNLTKDLLNELEV-----VKSRVKELECSESRLEKAELSLKDDL 498
Query: 473 NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTI 530
K+ L E N E I + + + L KN K+ + KV+ E+ + + + +
Sbjct: 499 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLK 558
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKN-SRG 586
+ +E +L +E +L KL ++ ELS ++L K+ +E+ ++ +RG
Sbjct: 559 SEMEE-----KVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRG 613
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++R EL NK E + E+ L++ L+ ++ +V+ + + D++++ F T
Sbjct: 614 RSRK---GSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVEGDLMKTEDEYDQLEQKFRT 669
Query: 647 LENKQQQI-HRLEKI 660
++K + +LE+I
Sbjct: 670 EQDKANFLSQQLEEI 684
Score = 70.1 bits (164), Expect = 2e-11
Identities = 78/413 (18%), Positives = 188/413 (45%), Gaps = 22/413 (5%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E + ER KL +EK + ++ R+ K+ +L + ++ L +M +Q
Sbjct: 205 EQERERLKKLLEQEKAYQARKE-KENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGL 263
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+ +++ +KLRE + + TS+ + R L ++ + + + + +H+ +L
Sbjct: 264 QSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN 323
Query: 381 DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
++ + +T+R IE E T LQ + ++EL+ KI + E + E
Sbjct: 324 QESHNRQLRLKLVGLTQR-IEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVEN 382
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKREKESEN------KIGIQ--QKLAAELLNKEEII 492
E++ E + TE + +++ + E ++ ++ QK +EL EE
Sbjct: 383 LRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAF 442
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI--ANCQESPNGISYQDLQQEIM 550
K + + +L ++ L ++K + + + +L+ + C ES + L+ ++
Sbjct: 443 SKSKSECTQL--HLNLEKEKNLT-KDLLNELEVVKSRVKELECSESRLEKAELSLKDDLT 499
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR-GQARVIKIREELIN------VLKN 603
LK + +V + + E + +++++++ +KN + Q +V+ + E+LI LK+
Sbjct: 500 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 559
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ E+ L + +L +++ +E + +++ D +++ +E +++I R
Sbjct: 560 EMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITR 612
Score = 52.8 bits (121), Expect = 4e-06
Identities = 76/436 (17%), Positives = 187/436 (42%), Gaps = 28/436 (6%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
+++L E L++ ++ + +++ R D I L++E + LE + E+ ++
Sbjct: 70 KKSLELSKEDLIQLLSIMEGELQARE---DVIHMLKTEKTKPEVLEAHYGSAEPEKVLRV 126
Query: 271 AIKEKLTTTESQLRQT--RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ + E + + ++++D+ + + + + + + E R+ +LE
Sbjct: 127 LHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE 186
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
K + + + T+ L Q+R+ L+ + + K + ++ + +L ++L + K
Sbjct: 187 KHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSF 246
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAE 447
+ + IE ++QD + E + K+ + KSK + + E+D E
Sbjct: 247 ALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDF--E 304
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK 507
+A++ +E+ +ES N+ +L +L+ + I +++ E KN++
Sbjct: 305 HKASR--FSQEHEEMNAKLANQESHNR-----QLRLKLVGLTQRIEELE----ETNKNLQ 353
Query: 508 LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS 567
E+++ Q +RD A C S ++L++ +++++ K ++ +
Sbjct: 354 KAEEEL----QELRDKIAK----GECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCR 405
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
E L KK QE E K R + ++ R + L+ ++ E L +LE +
Sbjct: 406 E-LRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 628 EVNKQIAAKADEIQEL 643
++ ++ ++EL
Sbjct: 465 DLLNELEVVKSRVKEL 480
Score = 46.4 bits (105), Expect = 3e-04
Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 16/275 (5%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
SR L L +LK+ V+ ++ ++ E R + + + E K+ DV
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-MDV 543
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
T ++ + + L+ +SE + + + E DE KL +E+ + S+L + + + K
Sbjct: 544 -TEKLIEESKKLLKLKSEMEEKVYNLTRERDE-LIGKLKSEEEKS---SELSCSVDLLKK 598
Query: 293 MDKQLREAEASIT---SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
+ E E IT S G+ + ++ KE+ LE +L++ L+ EV L++
Sbjct: 599 RLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIE--RLKKRLQQLEVVEGDLMKT 656
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEITKREIELKERTET 408
D + + LE K + E+ S QQLEE Q K E+ E+ +E EL+ R
Sbjct: 657 ED--EYDQLEQKFRTEQDKANFLS--QQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRL 712
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
E SR+ E+QA ++ + D ++ ++D
Sbjct: 713 EEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVD 747
Score = 39.9 bits (89), Expect = 0.030
Identities = 60/306 (19%), Positives = 141/306 (46%), Gaps = 24/306 (7%)
Query: 237 VMIDEIRELR-SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
V+ ++EL SES KA ++ +L + ++ + + ++ +++Q +V ++K
Sbjct: 472 VVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNK 531
Query: 296 QLREAEASITSLTGTV-----KMLEDQSRQKE--VQLEARARKLRESLKTGEVTTSQLIQ 348
+ + + +T + K+L+ +S +E L +L LK+ E +S+L
Sbjct: 532 NFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSC 591
Query: 349 QRDSLQAE---VLECKQQIEK--------LTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
D L+ + E +++I + LT + I++L ++++ K+ LQ Q E+ +
Sbjct: 592 SVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVE 650
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +K E + + + E+ +A + + + + + I+ E+ + + LR
Sbjct: 651 GDL-MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEK-GEVVSQEAELRH 708
Query: 458 TEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
R+ ++E + +++K+ EL+NKE+ + ++Q+ L + E K
Sbjct: 709 RFRLEEAKSRDLKAEVQ-ALKEKIH-ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMG 766
Query: 518 QYVRDL 523
Q V +L
Sbjct: 767 QEVLNL 772
>AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein.
Length = 1140
Score = 89.0 bits (211), Expect = 5e-17
Identities = 107/510 (20%), Positives = 240/510 (47%), Gaps = 43/510 (8%)
Query: 171 HLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ 230
H+ + Q ++ ++L+ + E+ + +T SK +R+ L+ + + ++ Q
Sbjct: 184 HIEQLGLQSQKVQDLTQKLREE-EEKLKAITSKSKE---DRQKLLKLEVDFEHKASRFSQ 239
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
+ E N + +E + K + + + E T K L E +L++ R+++
Sbjct: 240 EHEEMNAKLAN-QESHNRQLRLKLVGLTQRIEELEETNK-----NLQKAEEELQELRDKI 293
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQ 349
AK + A + +L V LE + + +E+ + E++ R+LR+ L+ E + +L +
Sbjct: 294 AKGECGNSSLMAEVENLRKRV--LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 351
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEITK---REIELK 403
+ LQ + E +++E+ + KS QL +L++ K + L + E+ K +E+E
Sbjct: 352 VEKLQKRMSEL-EKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 410
Query: 404 E----RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E + E L+D ++ +++ K+ ER++D + +V +
Sbjct: 411 ESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD------GLNKNFKVEQ 464
Query: 460 DEV--TTCKREKESENKIGIQQKLAAELLN----KEEIIGKMQIQ---TRELIKNIKLNE 510
+V T K +ES+ + ++ ++ ++ N ++E+IGK++ + + EL ++ L +
Sbjct: 465 GKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLK 524
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+++ E+ R++ + P ++L EI LK +L + +L +
Sbjct: 525 KRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTE 584
Query: 571 AKKDQELEQQDKNSRGQARVIKIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDE 628
+ DQ LEQ+ + + +A + + E I + KNK E+ E+ + + +L HR R+ +
Sbjct: 585 DEYDQ-LEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKG-EVVSQEAELRHRFRLEEA 642
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ + A+ ++E L NK+ Q+ +L+
Sbjct: 643 KSRDLKAEVQALKEKIHELMNKEDQLSQLQ 672
Score = 75.8 bits (178), Expect = 5e-13
Identities = 102/435 (23%), Positives = 205/435 (47%), Gaps = 34/435 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIK-EKLTTTESQLRQTRN-RVAKMDKQL 297
D ++LR E E KA+ E D ++ KL + E + SQ + N ++A +
Sbjct: 197 DLTQKLREEEEKLKAITSKSKE-DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHN 255
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
R+ + LT ++ LE+ ++ + + E ++LR+ + GE S L+ + ++L+ V
Sbjct: 256 RQLRLKLVGLTQRIEELEETNKNLQ-KAEEELQELRDKIAKGECGNSSLMAEVENLRKRV 314
Query: 358 LECK---QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
LE + ++I K Q + ++L+E+ +K E ++ KR EL E+ E S+
Sbjct: 315 LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSEL-EKLEEAFSKSK 373
Query: 415 NAIEELQAKIIELEKSKP-NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE-KESE 472
+ +L + LEK K DL E E+ +++ + L +E + + K+
Sbjct: 374 SECTQLH---LNLEKEKNLTKDLLNELEV-----VKSRVKELECSESRLEKAELSLKDDL 425
Query: 473 NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTI 530
K+ L E N E I + + + L KN K+ + KV+ E+ + + + +
Sbjct: 426 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLK 485
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKN-SRG 586
+ +E +L +E +L KL ++ ELS ++L K+ +E+ ++ +RG
Sbjct: 486 SEMEE-----KVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRG 540
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++R EL NK E + E+ L++ L+ ++ +V+ + + D++++ F T
Sbjct: 541 RSRK---GSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVEGDLMKTEDEYDQLEQKFRT 596
Query: 647 LENKQQQI-HRLEKI 660
++K + +LE+I
Sbjct: 597 EQDKANFLSQQLEEI 611
Score = 70.1 bits (164), Expect = 2e-11
Identities = 78/413 (18%), Positives = 188/413 (45%), Gaps = 22/413 (5%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E + ER KL +EK + ++ R+ K+ +L + ++ L +M +Q
Sbjct: 132 EQERERLKKLLEQEKAYQARKE-KENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGL 190
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+ +++ +KLRE + + TS+ + R L ++ + + + + +H+ +L
Sbjct: 191 QSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLAN 250
Query: 381 DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
++ + +T+R IE E T LQ + ++EL+ KI + E + E
Sbjct: 251 QESHNRQLRLKLVGLTQR-IEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVEN 309
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKREKESEN------KIGIQ--QKLAAELLNKEEII 492
E++ E + TE + +++ + E ++ ++ QK +EL EE
Sbjct: 310 LRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAF 369
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI--ANCQESPNGISYQDLQQEIM 550
K + + +L ++ L ++K + + + +L+ + C ES + L+ ++
Sbjct: 370 SKSKSECTQL--HLNLEKEKNLT-KDLLNELEVVKSRVKELECSESRLEKAELSLKDDLT 426
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR-GQARVIKIREELIN------VLKN 603
LK + +V + + E + +++++++ +KN + Q +V+ + E+LI LK+
Sbjct: 427 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 486
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ E+ L + +L +++ +E + +++ D +++ +E +++I R
Sbjct: 487 EMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITR 539
Score = 51.6 bits (118), Expect = 9e-06
Identities = 72/407 (17%), Positives = 172/407 (42%), Gaps = 25/407 (6%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQL 297
D I L++E + LE + E+ ++ ++ + E + + ++++D+
Sbjct: 23 DVIHMLKTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLE 82
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + + + E R+ +LE K + + + T+ L Q+R+ L+ +
Sbjct: 83 EKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLL 142
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ K + ++ + +L ++L + K + + IE ++QD +
Sbjct: 143 EQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKL 202
Query: 418 EELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG 476
E + K+ + KSK + + E+D E +A++ +E+ +ES N+
Sbjct: 203 REEEEKLKAITSKSKEDRQKLLKLEVDF--EHKASR--FSQEHEEMNAKLANQESHNR-- 256
Query: 477 IQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQES 536
+L +L+ + I +++ E KN++ E+++ Q +RD A C S
Sbjct: 257 ---QLRLKLVGLTQRIEELE----ETNKNLQKAEEEL----QELRDKIAK----GECGNS 301
Query: 537 PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREE 596
++L++ +++++ K ++ + E L KK QE E K R + ++ R
Sbjct: 302 SLMAEVENLRKRVLEMEGKDEEITKTESQCRE-LRKKLQEEEHHSKELRLEVEKLQKRMS 360
Query: 597 LINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
+ L+ ++ E L +LE + ++ ++ ++EL
Sbjct: 361 ELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKEL 407
Score = 46.4 bits (105), Expect = 3e-04
Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 16/275 (5%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
SR L L +LK+ V+ ++ ++ E R + + + E K+ DV
Sbjct: 412 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-MDV 470
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
T ++ + + L+ +SE + + + E DE KL +E+ + S+L + + + K
Sbjct: 471 -TEKLIEESKKLLKLKSEMEEKVYNLTRERDE-LIGKLKSEEEKS---SELSCSVDLLKK 525
Query: 293 MDKQLREAEASIT---SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
+ E E IT S G+ + ++ KE+ LE +L++ L+ EV L++
Sbjct: 526 RLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIE--RLKKRLQQLEVVEGDLMKT 583
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEITKREIELKERTET 408
D + + LE K + E+ S QQLEE Q K E+ E+ +E EL+ R
Sbjct: 584 ED--EYDQLEQKFRTEQDKANFLS--QQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRL 639
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
E SR+ E+QA ++ + D ++ ++D
Sbjct: 640 EEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVD 674
Score = 39.9 bits (89), Expect = 0.030
Identities = 60/306 (19%), Positives = 141/306 (46%), Gaps = 24/306 (7%)
Query: 237 VMIDEIRELR-SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
V+ ++EL SES KA ++ +L + ++ + + ++ +++Q +V ++K
Sbjct: 399 VVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNK 458
Query: 296 QLREAEASITSLTGTV-----KMLEDQSRQKE--VQLEARARKLRESLKTGEVTTSQLIQ 348
+ + + +T + K+L+ +S +E L +L LK+ E +S+L
Sbjct: 459 NFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSC 518
Query: 349 QRDSLQAE---VLECKQQIEK--------LTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
D L+ + E +++I + LT + I++L ++++ K+ LQ Q E+ +
Sbjct: 519 SVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVE 577
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +K E + + + E+ +A + + + + + I+ E+ + + LR
Sbjct: 578 GDL-MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEK-GEVVSQEAELRH 635
Query: 458 TEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
R+ ++E + +++K+ EL+NKE+ + ++Q+ L + E K
Sbjct: 636 RFRLEEAKSRDLKAEVQ-ALKEKIH-ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMG 693
Query: 518 QYVRDL 523
Q V +L
Sbjct: 694 QEVLNL 699
>AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens
cDNA FLJ14799 fis, clone NT2RP4001351, weakly similar to
Human ovarian cancer downregulated myosin heavy chain
homolog ).
Length = 965
Score = 87.8 bits (208), Expect = 1e-16
Identities = 107/510 (20%), Positives = 239/510 (46%), Gaps = 43/510 (8%)
Query: 171 HLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ 230
H+ + Q ++ ++L+ + E+ + +T SK +R+ L+ + + ++ Q
Sbjct: 9 HIEQLGLQSQKVQDLTQKLREE-EEKLKAITSKSKE---DRQKLLKLEVDFEHKASRFSQ 64
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
+ E N + +E + K + + + E T K L E +L++ R+++
Sbjct: 65 EHEEMNAKLAN-QESHNRQLRLKLVGLTQRIEELEETNK-----NLQKAEEELQELRDKI 118
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQ 349
AK + A + +L V LE + + +E+ + E++ R+LR+ L+ E + +L +
Sbjct: 119 AKGECGNSSLMAEVENLRKRV--LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 176
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEITK---REIELK 403
+ LQ + E +++E+ + KS QL +L++ K + L + E+ K +E+E
Sbjct: 177 VEKLQKRMSEL-EKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS 235
Query: 404 E----RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E + E L+D ++ +++ K+ ER++D + +V +
Sbjct: 236 ESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD------GLNKNFKVEQ 289
Query: 460 DEV--TTCKREKESENKIGIQQKLAAELLN----KEEIIGKMQIQ---TRELIKNIKLNE 510
+V T K +ES+ + ++ ++ ++ N ++E+IGK++ + + EL ++ L +
Sbjct: 290 GKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLK 349
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+++ E+ R++ + P ++L EI LK +L + +L +
Sbjct: 350 KRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTE 409
Query: 571 AKKDQELEQQDKNSRGQARVIKIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDE 628
+ DQ LEQ+ + + +A + + E I + KNK E+ E+ + + +L HR R+ +
Sbjct: 410 DEYDQ-LEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKG-EVVSQEAELRHRFRLEEA 467
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ + A ++E L NK+ Q+ +L+
Sbjct: 468 KSRDLKAGVQALKEKIHELMNKEDQLSQLQ 497
Score = 75.8 bits (178), Expect = 5e-13
Identities = 102/435 (23%), Positives = 205/435 (47%), Gaps = 34/435 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIK-EKLTTTESQLRQTRN-RVAKMDKQL 297
D ++LR E E KA+ E D ++ KL + E + SQ + N ++A +
Sbjct: 22 DLTQKLREEEEKLKAITSKSKE-DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHN 80
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
R+ + LT ++ LE+ ++ + + E ++LR+ + GE S L+ + ++L+ V
Sbjct: 81 RQLRLKLVGLTQRIEELEETNKNLQ-KAEEELQELRDKIAKGECGNSSLMAEVENLRKRV 139
Query: 358 LECK---QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
LE + ++I K Q + ++L+E+ +K E ++ KR EL E+ E S+
Sbjct: 140 LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSEL-EKLEEAFSKSK 198
Query: 415 NAIEELQAKIIELEKSKP-NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE-KESE 472
+ +L + LEK K DL E E+ +++ + L +E + + K+
Sbjct: 199 SECTQLH---LNLEKEKNLTKDLLNELEV-----VKSRVKELECSESRLEKAELSLKDDL 250
Query: 473 NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTI 530
K+ L E N E I + + + L KN K+ + KV+ E+ + + + +
Sbjct: 251 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLK 310
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKN-SRG 586
+ +E +L +E +L KL ++ ELS ++L K+ +E+ ++ +RG
Sbjct: 311 SEMEE-----KVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRG 365
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++R EL NK E + E+ L++ L+ ++ +V+ + + D++++ F T
Sbjct: 366 RSRK---GSELTCPEDNKIKELTLEIERLKKRLQ-QLEVVEGDLMKTEDEYDQLEQKFRT 421
Query: 647 LENKQQQI-HRLEKI 660
++K + +LE+I
Sbjct: 422 EQDKANFLSQQLEEI 436
Score = 40.7 bits (91), Expect = 0.017
Identities = 79/383 (20%), Positives = 166/383 (43%), Gaps = 34/383 (8%)
Query: 170 EHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLR 229
E +++ Q EL L+E + +++ V L KR + A ++ E +L
Sbjct: 147 EEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSK-SECTQLH 205
Query: 230 QDVET-RNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
++E +N+ D + EL K LE L++ A+L++K+ LT +S +
Sbjct: 206 LNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEK---AELSLKDDLTKLKSFTVMLVD 262
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQ 348
M +++++ E + L K+ + + +L ++KL + E L +
Sbjct: 263 ERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTR 322
Query: 349 QRDSLQAEVLECKQQIEKLTVQH---KSAIQQLEEDLKQTKRALQEQ-CEIT-KREIELK 403
+RD L ++ +++ +L+ K + +EE ++ R + E+T + ++K
Sbjct: 323 ERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIK 382
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER---EID----LWAELQATKETLR 456
E T E++ + +++L+ +L K++ D ++ E D L +L+ K +
Sbjct: 383 ELT-LEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIA 441
Query: 457 ----VTEDEVTTCKRE----------KESENKIGIQ--QKLAAELLNKEEIIGKMQIQTR 500
+ + EV + + E K + K G+Q ++ EL+NKE+ + ++Q+
Sbjct: 442 KNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAGVQALKEKIHELMNKEDQLSQLQVDYS 501
Query: 501 ELIKNIKLNEQKVIQYEQYVRDL 523
L + E K Q V +L
Sbjct: 502 VLQQRFMEEENKNKNMGQEVLNL 524
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 87.4 bits (207), Expect = 2e-16
Identities = 116/502 (23%), Positives = 228/502 (45%), Gaps = 49/502 (9%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
AL +L+ + ED VN++ + + L E+ + + KLR D+E ++ +
Sbjct: 152 ALDDLQAE-EDKVNSLNKTKSKLEQQVEDL----ESSLEQEKKLRVDLERNKRKLEG--D 204
Query: 245 LRSESENTKALEEMRHELDEERTAK----LAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
L+ E+ LE + +LDE K ++ K+ ++ Q + ++ ++ ++ E
Sbjct: 205 LKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL 264
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
E I + T E Q +LE + +L E+ G VT++Q I+ +AE L+
Sbjct: 265 EEEIEAERATRAKTEKQRSDYARELEELSERLEEA---GGVTSTQ-IELNKKREAEFLKL 320
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
++ +E+ T+QH++ + L + + L EQ + +R +K++ E E + + I++L
Sbjct: 321 RRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQR---VKQKLEKEKSEFKLEIDDL 377
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ + + KSK N + D +E + E ++ + E+TT K ++E +
Sbjct: 378 SSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTE-----AGE 432
Query: 481 LAAELLNKEEIIGKMQ-------IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
L+ +L KE I+ ++ QT EL + ++ E K + H+ +
Sbjct: 433 LSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLE-EENKAKNALAHALQSSRHDCDLLRE 491
Query: 534 QESPNGISYQDLQQ-------EIMDLKMKL-LDVVHRNEELSEI---LAKKDQELEQQDK 582
Q +LQ+ E+ + K D + R EEL E LA++ Q+ E+Q +
Sbjct: 492 QYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVE 551
Query: 583 NSRGQ-ARVIKIREELINVLKN--KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ A + K ++ L +++ + E++ LAA L+ + R D+V + K +E
Sbjct: 552 AVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA---LDKKQRNFDKVLAEWKTKCEE 608
Query: 640 IQ-ELFATLENKQQQIHRLEKI 660
Q EL A+L+ + L K+
Sbjct: 609 SQAELEASLKESRSLSTELFKL 630
Score = 71.7 bits (168), Expect = 8e-12
Identities = 110/504 (21%), Positives = 216/504 (42%), Gaps = 34/504 (6%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 49 ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 108
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL +EK E+ + + A+ DK L
Sbjct: 109 KVEKEKHATENKVKNLTEELSGLD-ETIAKLT-REKKALQEAHQQALDDLQAEEDKVNSL 166
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ ++ + ++ +Q ++ V LE RKL LK + + L + L E
Sbjct: 167 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLD-ER 225
Query: 358 LECKQ----QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
L+ K Q++ ++ Q ++ +K+ + ++E E + E + +TE + D
Sbjct: 226 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 285
Query: 414 RNAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC-KREKES 471
+EEL ++ E + +L +RE + + +E E V T K+ +S
Sbjct: 286 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS 345
Query: 472 ENKIGIQ---QKLAAELLNKEEIIGKMQI----QTRELIKNIKLNEQKVIQ-YEQYVRDL 523
++G Q + + L KE+ K++I + E + K N +K+ + E + +
Sbjct: 346 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 405
Query: 524 QAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLD---VVHRNEELSEILAKKDQE-- 576
+ N I Q S + ++ Q LQ E +L +L + +V + + ++ +E
Sbjct: 406 RGKNEEI---QRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 462
Query: 577 --LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA 634
LE+++K A ++ ++L+ + E+ A LQ+ L V + +
Sbjct: 463 RQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY- 521
Query: 635 AKADEIQELFATLENKQQQIHRLE 658
+ D IQ E K++ RL+
Sbjct: 522 -ETDAIQRTEELEEAKKKLAQRLQ 544
Score = 64.1 bits (149), Expect = 2e-09
Identities = 84/421 (19%), Positives = 183/421 (43%), Gaps = 37/421 (8%)
Query: 256 EEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE 315
++ + EL + + ++EKL T + + +V + L +AE
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC----------- 51
Query: 316 DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI 375
DQ + + QLEA+ +++ E + E ++L ++ L+ E E K+ I+ L +
Sbjct: 52 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 111
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA---KIIELEKSKP 432
++ + K +E + + +L + + + A+++LQA K+ L K+K
Sbjct: 112 KEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKS 171
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE--LLNKEE 490
+ E DL + L+ K+ LRV ++ KR+ E + K+ + L E +E
Sbjct: 172 KLEQQVE---DLESSLEQEKK-LRV---DLERNKRKLEGDLKLAQESILDLENDKQQLDE 224
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
+ K + +L ++ + +Q+++ +++LQA + E+ + +Q
Sbjct: 225 RLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR-S 283
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET---- 606
D +L ++ R EE + + Q + N + +A +K+R +L E
Sbjct: 284 DYARELEELSERLEEAGGVTS------TQIELNKKREAEFLKLRRDLEEATLQHEAMVAT 337
Query: 607 ---EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLA 663
+ + +A L + +++ R+ ++ K+ + EI +L +++E+ + LEKI
Sbjct: 338 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRT 397
Query: 664 L 664
L
Sbjct: 398 L 398
Score = 61.3 bits (142), Expect = 1e-08
Identities = 120/565 (21%), Positives = 245/565 (43%), Gaps = 59/565 (10%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LE+ D + +E++ K K NL ++ + + LS + E
Sbjct: 357 QRVKQKLEKEKSEFKLEIDDLSSSMESVSK-SKANL----EKICRTLEDQLSEARGKNEE 411
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAV----GEALVREVAKLRQDVETRNV 237
+ +L EL TQ +LS R E+ ++++ +A ++ +L++ +E N
Sbjct: 412 IQRSLSELTTQKSRLQTEAGELS-RQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK 470
Query: 238 MIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV-AKMDKQ 296
+ + S + L +R + +EE+ K ++ L+ S++ Q R + ++
Sbjct: 471 AKNALAHALQSSRHDCDL--LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 528
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE 356
E E + L ++ E+Q + A K ++ L+ GEV + +R + A
Sbjct: 529 TEELEEAKKKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQ-GEVEDLMVDVERANSLAA 586
Query: 357 VLECKQQ-IEKLTVQHKSAIQQ----LEEDLKQT----------KRALQE---QCEITKR 398
L+ KQ+ +K+ + K+ ++ LE LK++ K A +E Q E KR
Sbjct: 587 ALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKR 646
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL---WAELQATKETL 455
E + E E+ D I E I ELEKS+ +L + +I L AE E
Sbjct: 647 E---NKNLEQEIADLTEQIAENGKTIHELEKSRKQIEL-EKADIQLALEEAEAALEHEEA 702
Query: 456 RVTEDEVTTCKREKESENKIGIQQKLAAEL-LNKEEIIGKMQ--IQTRELIKNIKLNEQK 512
++ ++ + + E + KI + + +L N + + MQ + +N + +K
Sbjct: 703 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKK 762
Query: 513 VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK 572
++ + ++Q + AN Q + + +Q ++ D ++ L D + E+L E LA
Sbjct: 763 KMEGDLNEIEIQLSH---ANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 819
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ-QDLEHRMRIVDEVNK 631
++ + + QA V ++R L ++TE++R+LA + D R++++ N
Sbjct: 820 VER------RANLLQAEVEELRATL------EQTERARKLAEQELLDSNERVQLLHTQNT 867
Query: 632 QIAAKADEIQELFATLENKQQQIHR 656
+ +++ L+++ + R
Sbjct: 868 SLIHTKKKLETDLMQLQSEVEDASR 892
Score = 60.1 bits (139), Expect = 3e-08
Identities = 96/451 (21%), Positives = 192/451 (42%), Gaps = 30/451 (6%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+G +++ +L+ +E I+ R R+++E ++ + EL EE + +L +
Sbjct: 246 LGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRS--DYAREL-EELSERLEEAGGV 302
Query: 277 TTTESQLRQTRN-RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
T+T+ +L + R K+ + L EA ++ T++ S + + +++++
Sbjct: 303 TSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQK 362
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
L+ + I S V + K +EK+ ++ QL E + + + E+
Sbjct: 363 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKIC---RTLEDQLSEARGKNEEIQRSLSEL 419
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKET 454
T + K R +TE + +EE ++ + +L +SK TE + L E +A
Sbjct: 420 TTQ----KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 475
Query: 455 LRVTEDEVTTC-----KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ C + E+E E K +Q+ L+ N E + + +T + + +L
Sbjct: 476 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA--NSEVAQWRTKYETDAIQRTEELE 533
Query: 510 EQKVIQYEQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E K + Q ++D + + A C + Q LQ E+ DL ++DV N L+
Sbjct: 534 EAKK-KLAQRLQDSEEQVEAVNAKCASLEK--TKQRLQGEVEDL---MVDVERANS-LAA 586
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK + ++ + + + + + EL LK + S EL L+ E + ++
Sbjct: 587 ALDKKQRNFDKV--LAEWKTKCEESQAELEASLKESRS-LSTELFKLKNAYEEALDQLET 643
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
V ++ EI +L + + IH LEK
Sbjct: 644 VKRENKNLEQEIADLTEQIAENGKTIHELEK 674
Score = 58.8 bits (136), Expect = 6e-08
Identities = 102/451 (22%), Positives = 193/451 (42%), Gaps = 46/451 (10%)
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN---RVAKMDKQLREAEAS 303
S++E +L+E R E K A +E L E+ R+ +N +A + +Q+ E +
Sbjct: 609 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 668
Query: 304 ITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
I L + K +E + ++ LE A A E K + +L Q + + ++ E +
Sbjct: 669 IHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQL-ELTQVKSEIDRKIAEKDE 727
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR-EIELKERTETELQDS-RNAIEEL 420
+IE+L ++ ++ ++ L R+ E + K+ E +L E E +L + R A E L
Sbjct: 728 EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE-IEIQLSHANRQAAETL 786
Query: 421 Q-AKIIE--LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ + ++ L+ ++ + D + DL +L + + + EV + E +
Sbjct: 787 KHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA-- 844
Query: 478 QQKLAA-ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI---ANC 533
+KLA ELL+ E + + Q LI K E ++Q + V D R A
Sbjct: 845 -RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 903
Query: 534 QESPNGISYQDLQQEI----------MDLKMKLLDVVHRNEELSEILAK--KDQ------ 575
+ + ++L++E +L+ + D+ HR +E ++ K K Q
Sbjct: 904 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 963
Query: 576 -------ELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
ELE + K + + ++ E + L + E + + LQ DL ++++ +
Sbjct: 964 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQ-DLVDKLQVKVK 1022
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
K+ A +ADE T K Q H LE+
Sbjct: 1023 SYKRQAEEADEQANAHLTKFRKAQ--HELEE 1051
Score = 48.8 bits (111), Expect = 6e-05
Identities = 64/258 (24%), Positives = 112/258 (43%), Gaps = 20/258 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRA--CHERRT-LIAVGEALVREVAKLRQDVETRNV 237
EL L + + + A + D ++R H + T LI + L ++ +L+ +VE
Sbjct: 833 ELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVE---- 888
Query: 238 MIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL 297
D R+ R+ E K + EE + L + L QT V + +L
Sbjct: 889 --DASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRL 943
Query: 298 REAEA-SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSL 353
EAE ++ ++ LE + R+ E +LE +K ES+K E +L Q +
Sbjct: 944 DEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEED 1003
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ VL + ++KL V+ KS +Q EE +Q L + K + EL+E E +
Sbjct: 1004 RKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHL---TKFRKAQHELEE-AEERADIA 1059
Query: 414 RNAIEELQAKIIELEKSK 431
+ + +L+AK + S+
Sbjct: 1060 ESQVNKLRAKTRDFTSSR 1077
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 87.4 bits (207), Expect = 2e-16
Identities = 116/502 (23%), Positives = 228/502 (45%), Gaps = 49/502 (9%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
AL +L+ + ED VN++ + + L E+ + + KLR D+E ++ +
Sbjct: 1007 ALDDLQAE-EDKVNSLNKTKSKLEQQVEDL----ESSLEQEKKLRVDLERNKRKLEG--D 1059
Query: 245 LRSESENTKALEEMRHELDEERTAK----LAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
L+ E+ LE + +LDE K ++ K+ ++ Q + ++ ++ ++ E
Sbjct: 1060 LKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL 1119
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
E I + T E Q +LE + +L E+ G VT++Q I+ +AE L+
Sbjct: 1120 EEEIEAERATRAKTEKQRSDYARELEELSERLEEA---GGVTSTQ-IELNKKREAEFLKL 1175
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
++ +E+ T+QH++ + L + + L EQ + +R +K++ E E + + I++L
Sbjct: 1176 RRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQR---VKQKLEKEKSEFKLEIDDL 1232
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ + + KSK N + D +E + E ++ + E+TT K ++E +
Sbjct: 1233 SSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTE-----AGE 1287
Query: 481 LAAELLNKEEIIGKMQ-------IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
L+ +L KE I+ ++ QT EL + ++ E K + H+ +
Sbjct: 1288 LSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLE-EENKAKNALAHALQSSRHDCDLLRE 1346
Query: 534 QESPNGISYQDLQQ-------EIMDLKMKL-LDVVHRNEELSEI---LAKKDQELEQQDK 582
Q +LQ+ E+ + K D + R EEL E LA++ Q+ E+Q +
Sbjct: 1347 QYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVE 1406
Query: 583 NSRGQ-ARVIKIREELINVLKN--KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ A + K ++ L +++ + E++ LAA L+ + R D+V + K +E
Sbjct: 1407 AVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA---LDKKQRNFDKVLAEWKTKCEE 1463
Query: 640 IQ-ELFATLENKQQQIHRLEKI 660
Q EL A+L+ + L K+
Sbjct: 1464 SQAELEASLKESRSLSTELFKL 1485
Score = 72.1 bits (169), Expect = 6e-12
Identities = 118/551 (21%), Positives = 231/551 (41%), Gaps = 39/551 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 904 ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 963
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL +EK E+ + + A+ DK L
Sbjct: 964 KVEKEKHATENKVKNLTEELSGLD-ETIAKLT-REKKALQEAHQQALDDLQAEEDKVNSL 1021
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ ++ + ++ +Q ++ V LE RKL LK + + L + L E
Sbjct: 1022 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLD-ER 1080
Query: 358 LECKQ----QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
L+ K Q++ ++ Q ++ +K+ + ++E E + E + +TE + D
Sbjct: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
Query: 414 RNAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC-KREKES 471
+EEL ++ E + +L +RE + + +E E V T K+ +S
Sbjct: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS 1200
Query: 472 ENKIGIQ---QKLAAELLNKEEIIGKMQI----QTRELIKNIKLNEQKVIQ-YEQYVRDL 523
++G Q + + L KE+ K++I + E + K N +K+ + E + +
Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260
Query: 524 QAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLD---VVHRNEELSEILAKKDQE-- 576
+ N I Q S + ++ Q LQ E +L +L + +V + + ++ +E
Sbjct: 1261 RGKNEEI---QRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 1317
Query: 577 --LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA 634
LE+++K A ++ ++L+ + E+ A LQ+ L V + +
Sbjct: 1318 RQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYE 1377
Query: 635 AKA-DEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAAL------EH 687
A +EL E Q++ E+ V A+ ++ L +
Sbjct: 1378 TDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 1437
Query: 688 ELAAGLNRKER 698
LAA L++K+R
Sbjct: 1438 SLAAALDKKQR 1448
Score = 64.5 bits (150), Expect = 1e-09
Identities = 88/438 (20%), Positives = 188/438 (42%), Gaps = 40/438 (9%)
Query: 242 IRELRSESENTKALEEM---RHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLR 298
++ +E E EE + EL + + ++EKL T + + +V + L
Sbjct: 841 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLL 900
Query: 299 EAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
+AE DQ + + QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 901 DAEERC-----------DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS 949
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIE 418
E K+ I+ L + ++ + K +E + + +L + + + A++
Sbjct: 950 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALD 1009
Query: 419 ELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+LQA K+ L K+K + E DL + L+ K+ LRV ++ KR+ E + K+
Sbjct: 1010 DLQAEEDKVNSLNKTKSKLEQQVE---DLESSLEQEKK-LRV---DLERNKRKLEGDLKL 1062
Query: 476 GIQQKLAAE--LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
+ L E +E + K + +L ++ + +Q+++ +++LQA +
Sbjct: 1063 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE 1122
Query: 534 QESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
E+ + +Q D +L ++ R EE + + Q + N + +A +K+
Sbjct: 1123 IEAERATRAKTEKQR-SDYARELEELSERLEEAGGVTS------TQIELNKKREAEFLKL 1175
Query: 594 REELINVLKNKET-------EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
R +L E + + +A L + +++ R+ ++ K+ + EI +L ++
Sbjct: 1176 RRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSS 1235
Query: 647 LENKQQQIHRLEKIVLAL 664
+E+ + LEKI L
Sbjct: 1236 MESVSKSKANLEKICRTL 1253
Score = 61.3 bits (142), Expect = 1e-08
Identities = 120/565 (21%), Positives = 245/565 (43%), Gaps = 59/565 (10%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LE+ D + +E++ K K NL ++ + + LS + E
Sbjct: 1212 QRVKQKLEKEKSEFKLEIDDLSSSMESVSK-SKANL----EKICRTLEDQLSEARGKNEE 1266
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAV----GEALVREVAKLRQDVETRNV 237
+ +L EL TQ +LS R E+ ++++ +A ++ +L++ +E N
Sbjct: 1267 IQRSLSELTTQKSRLQTEAGELS-RQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK 1325
Query: 238 MIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV-AKMDKQ 296
+ + S + L +R + +EE+ K ++ L+ S++ Q R + ++
Sbjct: 1326 AKNALAHALQSSRHDCDL--LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1383
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE 356
E E + L ++ E+Q + A K ++ L+ GEV + +R + A
Sbjct: 1384 TEELEEAQEKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQ-GEVEDLMVDVERANSLAA 1441
Query: 357 VLECKQQ-IEKLTVQHKSAIQQ----LEEDLKQT----------KRALQE---QCEITKR 398
L+ KQ+ +K+ + K+ ++ LE LK++ K A +E Q E KR
Sbjct: 1442 ALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKR 1501
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL---WAELQATKETL 455
E + E E+ D I E I ELEKS+ +L + +I L AE E
Sbjct: 1502 E---NKNLEQEIADLTEQIAENGKTIHELEKSRKQIEL-EKADIQLALEEAEAALEHEEA 1557
Query: 456 RVTEDEVTTCKREKESENKIGIQQKLAAEL-LNKEEIIGKMQ--IQTRELIKNIKLNEQK 512
++ ++ + + E + KI + + +L N + + MQ + +N + +K
Sbjct: 1558 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKK 1617
Query: 513 VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK 572
++ + ++Q + AN Q + + +Q ++ D ++ L D + E+L E LA
Sbjct: 1618 KMEGDLNEIEIQLSH---ANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 1674
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ-QDLEHRMRIVDEVNK 631
++ + + QA V ++R L ++TE++R+LA + D R++++ N
Sbjct: 1675 VER------RANLLQAEVEELRATL------EQTERARKLAEQELLDSNERVQLLHTQNT 1722
Query: 632 QIAAKADEIQELFATLENKQQQIHR 656
+ +++ L+++ + R
Sbjct: 1723 SLIHTKKKLETDLMQLQSEVEDASR 1747
Score = 58.8 bits (136), Expect = 6e-08
Identities = 102/451 (22%), Positives = 193/451 (42%), Gaps = 46/451 (10%)
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN---RVAKMDKQLREAEAS 303
S++E +L+E R E K A +E L E+ R+ +N +A + +Q+ E +
Sbjct: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 1523
Query: 304 ITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
I L + K +E + ++ LE A A E K + +L Q + + ++ E +
Sbjct: 1524 IHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQL-ELTQVKSEIDRKIAEKDE 1582
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR-EIELKERTETELQDS-RNAIEEL 420
+IE+L ++ ++ ++ L R+ E + K+ E +L E E +L + R A E L
Sbjct: 1583 EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE-IEIQLSHANRQAAETL 1641
Query: 421 Q-AKIIE--LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ + ++ L+ ++ + D + DL +L + + + EV + E +
Sbjct: 1642 KHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA-- 1699
Query: 478 QQKLAA-ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI---ANC 533
+KLA ELL+ E + + Q LI K E ++Q + V D R A
Sbjct: 1700 -RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 1758
Query: 534 QESPNGISYQDLQQEI----------MDLKMKLLDVVHRNEELSEILAK--KDQ------ 575
+ + ++L++E +L+ + D+ HR +E ++ K K Q
Sbjct: 1759 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818
Query: 576 -------ELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
ELE + K + + ++ E + L + E + + LQ DL ++++ +
Sbjct: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQ-DLVDKLQVKVK 1877
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
K+ A +ADE T K Q H LE+
Sbjct: 1878 SYKRQAEEADEQANAHLTKFRKAQ--HELEE 1906
Score = 58.4 bits (135), Expect = 8e-08
Identities = 95/451 (21%), Positives = 192/451 (42%), Gaps = 30/451 (6%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+G +++ +L+ +E I+ R R+++E ++ + EL EE + +L +
Sbjct: 1101 LGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRS--DYAREL-EELSERLEEAGGV 1157
Query: 277 TTTESQLRQTRN-RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
T+T+ +L + R K+ + L EA ++ T++ S + + +++++
Sbjct: 1158 TSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQK 1217
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
L+ + I S V + K +EK+ ++ QL E + + + E+
Sbjct: 1218 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKIC---RTLEDQLSEARGKNEEIQRSLSEL 1274
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKET 454
T + K R +TE + +EE ++ + +L +SK TE + L E +A
Sbjct: 1275 TTQ----KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 1330
Query: 455 LRVTEDEVTTC-----KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ C + E+E E K +Q+ L+ N E + + +T + + +L
Sbjct: 1331 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA--NSEVAQWRTKYETDAIQRTEELE 1388
Query: 510 EQKVIQYEQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E + + Q ++D + + A C + Q LQ E+ DL ++DV N L+
Sbjct: 1389 EAQE-KLAQRLQDSEEQVEAVNAKCASLEK--TKQRLQGEVEDL---MVDVERANS-LAA 1441
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK + ++ + + + + + EL LK + S EL L+ E + ++
Sbjct: 1442 ALDKKQRNFDKV--LAEWKTKCEESQAELEASLKESRS-LSTELFKLKNAYEEALDQLET 1498
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
V ++ EI +L + + IH LEK
Sbjct: 1499 VKRENKNLEQEIADLTEQIAENGKTIHELEK 1529
Score = 48.8 bits (111), Expect = 6e-05
Identities = 64/258 (24%), Positives = 112/258 (43%), Gaps = 20/258 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRA--CHERRT-LIAVGEALVREVAKLRQDVETRNV 237
EL L + + + A + D ++R H + T LI + L ++ +L+ +VE
Sbjct: 1688 ELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVE---- 1743
Query: 238 MIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL 297
D R+ R+ E K + EE + L + L QT V + +L
Sbjct: 1744 --DASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRL 1798
Query: 298 REAEA-SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSL 353
EAE ++ ++ LE + R+ E +LE +K ES+K E +L Q +
Sbjct: 1799 DEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEED 1858
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ VL + ++KL V+ KS +Q EE +Q L + K + EL+E E +
Sbjct: 1859 RKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHL---TKFRKAQHELEE-AEERADIA 1914
Query: 414 RNAIEELQAKIIELEKSK 431
+ + +L+AK + S+
Sbjct: 1915 ESQVNKLRAKTRDFTSSR 1932
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 87.4 bits (207), Expect = 2e-16
Identities = 116/502 (23%), Positives = 228/502 (45%), Gaps = 49/502 (9%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
AL +L+ + ED VN++ + + L E+ + + KLR D+E ++ +
Sbjct: 234 ALDDLQAE-EDKVNSLNKTKSKLEQQVEDL----ESSLEQEKKLRVDLERNKRKLEG--D 286
Query: 245 LRSESENTKALEEMRHELDEERTAK----LAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
L+ E+ LE + +LDE K ++ K+ ++ Q + ++ ++ ++ E
Sbjct: 287 LKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL 346
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
E I + T E Q +LE + +L E+ G VT++Q I+ +AE L+
Sbjct: 347 EEEIEAERATRAKTEKQRSDYARELEELSERLEEA---GGVTSTQ-IELNKKREAEFLKL 402
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
++ +E+ T+QH++ + L + + L EQ + +R +K++ E E + + I++L
Sbjct: 403 RRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQR---VKQKLEKEKSEFKLEIDDL 459
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ + + KSK N + D +E + E ++ + E+TT K ++E +
Sbjct: 460 SSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTE-----AGE 514
Query: 481 LAAELLNKEEIIGKMQ-------IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
L+ +L KE I+ ++ QT EL + ++ E K + H+ +
Sbjct: 515 LSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLE-EENKAKNALAHALQSSRHDCDLLRE 573
Query: 534 QESPNGISYQDLQQ-------EIMDLKMKL-LDVVHRNEELSEI---LAKKDQELEQQDK 582
Q +LQ+ E+ + K D + R EEL E LA++ Q+ E+Q +
Sbjct: 574 QYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVE 633
Query: 583 NSRGQ-ARVIKIREELINVLKN--KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ A + K ++ L +++ + E++ LAA L+ + R D+V + K +E
Sbjct: 634 AVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA---LDKKQRNFDKVLAEWKTKCEE 690
Query: 640 IQ-ELFATLENKQQQIHRLEKI 660
Q EL A+L+ + L K+
Sbjct: 691 SQAELEASLKESRSLSTELFKL 712
Score = 72.1 bits (169), Expect = 6e-12
Identities = 118/551 (21%), Positives = 231/551 (41%), Gaps = 39/551 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 131 ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 190
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL +EK E+ + + A+ DK L
Sbjct: 191 KVEKEKHATENKVKNLTEELSGLD-ETIAKLT-REKKALQEAHQQALDDLQAEEDKVNSL 248
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ ++ + ++ +Q ++ V LE RKL LK + + L + L E
Sbjct: 249 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLD-ER 307
Query: 358 LECKQ----QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
L+ K Q++ ++ Q ++ +K+ + ++E E + E + +TE + D
Sbjct: 308 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 367
Query: 414 RNAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC-KREKES 471
+EEL ++ E + +L +RE + + +E E V T K+ +S
Sbjct: 368 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS 427
Query: 472 ENKIGIQ---QKLAAELLNKEEIIGKMQI----QTRELIKNIKLNEQKVIQ-YEQYVRDL 523
++G Q + + L KE+ K++I + E + K N +K+ + E + +
Sbjct: 428 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 487
Query: 524 QAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLD---VVHRNEELSEILAKKDQE-- 576
+ N I Q S + ++ Q LQ E +L +L + +V + + ++ +E
Sbjct: 488 RGKNEEI---QRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 544
Query: 577 --LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA 634
LE+++K A ++ ++L+ + E+ A LQ+ L V + +
Sbjct: 545 RQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYE 604
Query: 635 AKA-DEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAAL------EH 687
A +EL E Q++ E+ V A+ ++ L +
Sbjct: 605 TDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 664
Query: 688 ELAAGLNRKER 698
LAA L++K+R
Sbjct: 665 SLAAALDKKQR 675
Score = 64.5 bits (150), Expect = 1e-09
Identities = 88/438 (20%), Positives = 188/438 (42%), Gaps = 40/438 (9%)
Query: 242 IRELRSESENTKALEEM---RHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLR 298
++ +E E EE + EL + + ++EKL T + + +V + L
Sbjct: 68 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLL 127
Query: 299 EAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
+AE DQ + + QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 128 DAEERC-----------DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECS 176
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIE 418
E K+ I+ L + ++ + K +E + + +L + + + A++
Sbjct: 177 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALD 236
Query: 419 ELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+LQA K+ L K+K + E DL + L+ K+ LRV ++ KR+ E + K+
Sbjct: 237 DLQAEEDKVNSLNKTKSKLEQQVE---DLESSLEQEKK-LRV---DLERNKRKLEGDLKL 289
Query: 476 GIQQKLAAE--LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
+ L E +E + K + +L ++ + +Q+++ +++LQA +
Sbjct: 290 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE 349
Query: 534 QESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
E+ + +Q D +L ++ R EE + + Q + N + +A +K+
Sbjct: 350 IEAERATRAKTEKQR-SDYARELEELSERLEEAGGVTS------TQIELNKKREAEFLKL 402
Query: 594 REELINVLKNKET-------EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
R +L E + + +A L + +++ R+ ++ K+ + EI +L ++
Sbjct: 403 RRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSS 462
Query: 647 LENKQQQIHRLEKIVLAL 664
+E+ + LEKI L
Sbjct: 463 MESVSKSKANLEKICRTL 480
Score = 61.7 bits (143), Expect = 9e-09
Identities = 120/565 (21%), Positives = 245/565 (43%), Gaps = 59/565 (10%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LE+ D + +E++ K K NL ++ + + LS + E
Sbjct: 439 QRVKQKLEKEKSEFKLEIDDLSSSMESVSK-SKANL----EKICRTLEDQLSEARGKNEE 493
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAV----GEALVREVAKLRQDVETRNV 237
+ +L EL TQ +LS R E+ ++++ +A ++ +L++ +E N
Sbjct: 494 IQRSLSELTTQKSRLQTEAGELS-RQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK 552
Query: 238 MIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV-AKMDKQ 296
+ + S + L +R + +EE+ K ++ L+ S++ Q R + ++
Sbjct: 553 AKNALAHALQSSRHDCDL--LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 610
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE 356
E E + L ++ E+Q + A K ++ L+ GEV + +R + A
Sbjct: 611 TEELEEAQEKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQ-GEVEDLMVDVERANSLAA 668
Query: 357 VLECKQQ-IEKLTVQHKSAIQQ----LEEDLKQT----------KRALQE---QCEITKR 398
L+ KQ+ +K+ + K+ ++ LE LK++ K A +E Q E KR
Sbjct: 669 ALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKR 728
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL---WAELQATKETL 455
E + E E+ D I E I ELEKS+ +L + +I L AE E
Sbjct: 729 E---NKNLEQEIADLTEQIAENGKTIHELEKSRKQIEL-EKADIQLALEEAEAALEHEEA 784
Query: 456 RVTEDEVTTCKREKESENKIGIQQKLAAEL-LNKEEIIGKMQ--IQTRELIKNIKLNEQK 512
++ ++ + + E + KI + + +L N + + MQ + +N + +K
Sbjct: 785 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKK 844
Query: 513 VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK 572
++ + ++Q + AN Q + + +Q ++ D ++ L D + E+L E LA
Sbjct: 845 KMEGDLNEIEIQLSH---ANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQEDLKEQLAI 901
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ-QDLEHRMRIVDEVNK 631
++ + + QA V ++R L ++TE++R+LA + D R++++ N
Sbjct: 902 VER------RANLLQAEVEELRATL------EQTERARKLAEQELLDSNERVQLLHTQNT 949
Query: 632 QIAAKADEIQELFATLENKQQQIHR 656
+ +++ L+++ + R
Sbjct: 950 SLIHTKKKLETDLMQLQSEVEDASR 974
Score = 60.1 bits (139), Expect = 3e-08
Identities = 102/451 (22%), Positives = 194/451 (43%), Gaps = 46/451 (10%)
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN---RVAKMDKQLREAEAS 303
S++E +L+E R E K A +E L E+ R+ +N +A + +Q+ E +
Sbjct: 691 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 750
Query: 304 ITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
I L + K +E + ++ LE A A E K + +L Q + + ++ E +
Sbjct: 751 IHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQL-ELTQVKSEIDRKIAEKDE 809
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR-EIELKERTETELQDS-RNAIEEL 420
+IE+L ++ ++ ++ L R+ E + K+ E +L E E +L + R A E L
Sbjct: 810 EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE-IEIQLSHANRQAAETL 868
Query: 421 Q-AKIIE--LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ + ++ L+ ++ + D + + DL +L + + + EV + E +
Sbjct: 869 KHLRSVQGQLKDTQLHLDDALQTQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA-- 926
Query: 478 QQKLAA-ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI---ANC 533
+KLA ELL+ E + + Q LI K E ++Q + V D R A
Sbjct: 927 -RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 985
Query: 534 QESPNGISYQDLQQEI----------MDLKMKLLDVVHRNEELSEILAK--KDQ------ 575
+ + ++L++E +L+ + D+ HR +E ++ K K Q
Sbjct: 986 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1045
Query: 576 -------ELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
ELE + K + + ++ E + L + E + + LQ DL ++++ +
Sbjct: 1046 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQ-DLVDKLQVKVK 1104
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
K+ A +ADE T K Q H LE+
Sbjct: 1105 SYKRQAEEADEQANAHLTKFRKAQ--HELEE 1133
Score = 58.4 bits (135), Expect = 8e-08
Identities = 95/451 (21%), Positives = 192/451 (42%), Gaps = 30/451 (6%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+G +++ +L+ +E I+ R R+++E ++ + EL EE + +L +
Sbjct: 328 LGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRS--DYAREL-EELSERLEEAGGV 384
Query: 277 TTTESQLRQTRN-RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
T+T+ +L + R K+ + L EA ++ T++ S + + +++++
Sbjct: 385 TSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQK 444
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
L+ + I S V + K +EK+ ++ QL E + + + E+
Sbjct: 445 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKIC---RTLEDQLSEARGKNEEIQRSLSEL 501
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKET 454
T + K R +TE + +EE ++ + +L +SK TE + L E +A
Sbjct: 502 TTQ----KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 557
Query: 455 LRVTEDEVTTC-----KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ C + E+E E K +Q+ L+ N E + + +T + + +L
Sbjct: 558 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA--NSEVAQWRTKYETDAIQRTEELE 615
Query: 510 EQKVIQYEQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E + + Q ++D + + A C + Q LQ E+ DL ++DV N L+
Sbjct: 616 EAQE-KLAQRLQDSEEQVEAVNAKCASLEK--TKQRLQGEVEDL---MVDVERANS-LAA 668
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK + ++ + + + + + EL LK + S EL L+ E + ++
Sbjct: 669 ALDKKQRNFDKV--LAEWKTKCEESQAELEASLKESRS-LSTELFKLKNAYEEALDQLET 725
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
V ++ EI +L + + IH LEK
Sbjct: 726 VKRENKNLEQEIADLTEQIAENGKTIHELEK 756
Score = 52.0 bits (119), Expect = 7e-06
Identities = 72/310 (23%), Positives = 130/310 (41%), Gaps = 16/310 (5%)
Query: 130 SSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALREL 189
S A E L ++ +K + +L + QT D+ E L+ + L + EL
Sbjct: 858 SHANRQAAETLKHLRSVQGQLKDTQLHLD-DALQTQEDLKEQLAIVERRANLLQAEVEEL 916
Query: 190 KTQAE--DAVNTVTDLSKRACHERRTLIAV-GEALVREVAKLRQDV-ETRNVMIDEIREL 245
+ E + + + +ER L+ +L+ KL D+ + ++ + D R+
Sbjct: 917 RATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDA 976
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SI 304
R+ E K + EE + L + L QT V + +L EAE ++
Sbjct: 977 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRLDEAEQLAL 1033
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECK 361
++ LE + R+ E +LE +K ES+K E +L Q + + VL +
Sbjct: 1034 KGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQ 1093
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
++KL V+ KS +Q EE +Q L + K + EL+E E + + + +L+
Sbjct: 1094 DLVDKLQVKVKSYKRQAEEADEQANAHL---TKFRKAQHELEE-AEERADIAESQVNKLR 1149
Query: 422 AKIIELEKSK 431
AK + S+
Sbjct: 1150 AKTRDFTSSR 1159
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 87.4 bits (207), Expect = 2e-16
Identities = 116/502 (23%), Positives = 228/502 (45%), Gaps = 49/502 (9%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
AL +L+ + ED VN++ + + L E+ + + KLR D+E ++ +
Sbjct: 8 ALDDLQAE-EDKVNSLNKTKSKLEQQVEDL----ESSLEQEKKLRVDLERNKRKLEG--D 60
Query: 245 LRSESENTKALEEMRHELDEERTAK----LAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
L+ E+ LE + +LDE K ++ K+ ++ Q + ++ ++ ++ E
Sbjct: 61 LKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL 120
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
E I + T E Q +LE + +L E+ G VT++Q I+ +AE L+
Sbjct: 121 EEEIEAERATRAKTEKQRSDYARELEELSERLEEA---GGVTSTQ-IELNKKREAEFLKL 176
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
++ +E+ T+QH++ + L + + L EQ + +R +K++ E E + + I++L
Sbjct: 177 RRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQR---VKQKLEKEKSEFKLEIDDL 233
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ + + KSK N + D +E + E ++ + E+TT K ++E +
Sbjct: 234 SSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTE-----AGE 288
Query: 481 LAAELLNKEEIIGKMQ-------IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
L+ +L KE I+ ++ QT EL + ++ E K + H+ +
Sbjct: 289 LSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLE-EENKAKNALAHALQSSRHDCDLLRE 347
Query: 534 QESPNGISYQDLQQ-------EIMDLKMKL-LDVVHRNEELSEI---LAKKDQELEQQDK 582
Q +LQ+ E+ + K D + R EEL E LA++ Q+ E+Q +
Sbjct: 348 QYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVE 407
Query: 583 NSRGQ-ARVIKIREELINVLKN--KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ A + K ++ L +++ + E++ LAA L+ + R D+V + K +E
Sbjct: 408 AVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA---LDKKQRNFDKVLAEWKTKCEE 464
Query: 640 IQ-ELFATLENKQQQIHRLEKI 660
Q EL A+L+ + L K+
Sbjct: 465 SQAELEASLKESRSLSTELFKL 486
Score = 61.3 bits (142), Expect = 1e-08
Identities = 120/565 (21%), Positives = 245/565 (43%), Gaps = 59/565 (10%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LE+ D + +E++ K K NL ++ + + LS + E
Sbjct: 213 QRVKQKLEKEKSEFKLEIDDLSSSMESVSK-SKANL----EKICRTLEDQLSEARGKNEE 267
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAV----GEALVREVAKLRQDVETRNV 237
+ +L EL TQ +LS R E+ ++++ +A ++ +L++ +E N
Sbjct: 268 IQRSLSELTTQKSRLQTEAGELS-RQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK 326
Query: 238 MIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV-AKMDKQ 296
+ + S + L +R + +EE+ K ++ L+ S++ Q R + ++
Sbjct: 327 AKNALAHALQSSRHDCDL--LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 384
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE 356
E E + L ++ E+Q + A K ++ L+ GEV + +R + A
Sbjct: 385 TEELEEAKKKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQ-GEVEDLMVDVERANSLAA 442
Query: 357 VLECKQQ-IEKLTVQHKSAIQQ----LEEDLKQT----------KRALQE---QCEITKR 398
L+ KQ+ +K+ + K+ ++ LE LK++ K A +E Q E KR
Sbjct: 443 ALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKR 502
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL---WAELQATKETL 455
E + E E+ D I E I ELEKS+ +L + +I L AE E
Sbjct: 503 E---NKNLEQEIADLTEQIAENGKTIHELEKSRKQIEL-EKADIQLALEEAEAALEHEEA 558
Query: 456 RVTEDEVTTCKREKESENKIGIQQKLAAEL-LNKEEIIGKMQ--IQTRELIKNIKLNEQK 512
++ ++ + + E + KI + + +L N + + MQ + +N + +K
Sbjct: 559 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKK 618
Query: 513 VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK 572
++ + ++Q + AN Q + + +Q ++ D ++ L D + E+L E LA
Sbjct: 619 KMEGDLNEIEIQLSH---ANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 675
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ-QDLEHRMRIVDEVNK 631
++ + + QA V ++R L ++TE++R+LA + D R++++ N
Sbjct: 676 VER------RANLLQAEVEELRATL------EQTERARKLAEQELLDSNERVQLLHTQNT 723
Query: 632 QIAAKADEIQELFATLENKQQQIHR 656
+ +++ L+++ + R
Sbjct: 724 SLIHTKKKLETDLMQLQSEVEDASR 748
Score = 60.1 bits (139), Expect = 3e-08
Identities = 96/451 (21%), Positives = 192/451 (42%), Gaps = 30/451 (6%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+G +++ +L+ +E I+ R R+++E ++ + EL EE + +L +
Sbjct: 102 LGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRS--DYAREL-EELSERLEEAGGV 158
Query: 277 TTTESQLRQTRN-RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
T+T+ +L + R K+ + L EA ++ T++ S + + +++++
Sbjct: 159 TSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQK 218
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
L+ + I S V + K +EK+ ++ QL E + + + E+
Sbjct: 219 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKIC---RTLEDQLSEARGKNEEIQRSLSEL 275
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKET 454
T + K R +TE + +EE ++ + +L +SK TE + L E +A
Sbjct: 276 TTQ----KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 331
Query: 455 LRVTEDEVTTC-----KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ C + E+E E K +Q+ L+ N E + + +T + + +L
Sbjct: 332 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA--NSEVAQWRTKYETDAIQRTEELE 389
Query: 510 EQKVIQYEQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E K + Q ++D + + A C + Q LQ E+ DL ++DV N L+
Sbjct: 390 EAKK-KLAQRLQDSEEQVEAVNAKCASLEK--TKQRLQGEVEDL---MVDVERANS-LAA 442
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK + ++ + + + + + EL LK + S EL L+ E + ++
Sbjct: 443 ALDKKQRNFDKV--LAEWKTKCEESQAELEASLKESRS-LSTELFKLKNAYEEALDQLET 499
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
V ++ EI +L + + IH LEK
Sbjct: 500 VKRENKNLEQEIADLTEQIAENGKTIHELEK 530
Score = 58.8 bits (136), Expect = 6e-08
Identities = 102/451 (22%), Positives = 193/451 (42%), Gaps = 46/451 (10%)
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN---RVAKMDKQLREAEAS 303
S++E +L+E R E K A +E L E+ R+ +N +A + +Q+ E +
Sbjct: 465 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 524
Query: 304 ITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
I L + K +E + ++ LE A A E K + +L Q + + ++ E +
Sbjct: 525 IHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQL-ELTQVKSEIDRKIAEKDE 583
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR-EIELKERTETELQDS-RNAIEEL 420
+IE+L ++ ++ ++ L R+ E + K+ E +L E E +L + R A E L
Sbjct: 584 EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE-IEIQLSHANRQAAETL 642
Query: 421 Q-AKIIE--LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ + ++ L+ ++ + D + DL +L + + + EV + E +
Sbjct: 643 KHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA-- 700
Query: 478 QQKLAA-ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI---ANC 533
+KLA ELL+ E + + Q LI K E ++Q + V D R A
Sbjct: 701 -RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 759
Query: 534 QESPNGISYQDLQQEI----------MDLKMKLLDVVHRNEELSEILAK--KDQ------ 575
+ + ++L++E +L+ + D+ HR +E ++ K K Q
Sbjct: 760 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 819
Query: 576 -------ELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
ELE + K + + ++ E + L + E + + LQ DL ++++ +
Sbjct: 820 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQ-DLVDKLQVKVK 878
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
K+ A +ADE T K Q H LE+
Sbjct: 879 SYKRQAEEADEQANAHLTKFRKAQ--HELEE 907
Score = 48.8 bits (111), Expect = 6e-05
Identities = 64/258 (24%), Positives = 112/258 (43%), Gaps = 20/258 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRA--CHERRT-LIAVGEALVREVAKLRQDVETRNV 237
EL L + + + A + D ++R H + T LI + L ++ +L+ +VE
Sbjct: 689 ELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVE---- 744
Query: 238 MIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL 297
D R+ R+ E K + EE + L + L QT V + +L
Sbjct: 745 --DASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRL 799
Query: 298 REAEA-SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSL 353
EAE ++ ++ LE + R+ E +LE +K ES+K E +L Q +
Sbjct: 800 DEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEED 859
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ VL + ++KL V+ KS +Q EE +Q L + K + EL+E E +
Sbjct: 860 RKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHL---TKFRKAQHELEE-AEERADIA 915
Query: 414 RNAIEELQAKIIELEKSK 431
+ + +L+AK + S+
Sbjct: 916 ESQVNKLRAKTRDFTSSR 933
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 87.0 bits (206), Expect = 2e-16
Identities = 116/502 (23%), Positives = 228/502 (45%), Gaps = 49/502 (9%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
AL +L+ + ED VN++ + + L E+ + + KLR D+E ++ +
Sbjct: 152 ALDDLQAE-EDKVNSLNKTKSKLEQQVEDL----ESSLEQEKKLRVDLERNKRKLEG--D 204
Query: 245 LRSESENTKALEEMRHELDEERTAK----LAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
L+ E+ LE + +LDE K ++ K+ ++ Q + ++ ++ ++ E
Sbjct: 205 LKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL 264
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
E I + T E Q +LE + +L E+ G VT++Q I+ +AE L+
Sbjct: 265 EEEIEAERATRAKTEKQRSDYARELEELSERLEEA---GGVTSTQ-IELNKKREAEFLKL 320
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
++ +E+ T+QH++ + L + + L EQ + +R +K++ E E + + I++L
Sbjct: 321 RRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQR---VKQKLEKEKSEFKLEIDDL 377
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ + + KSK N + D +E + E ++ + E+TT K ++E +
Sbjct: 378 SSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTE-----AGE 432
Query: 481 LAAELLNKEEIIGKMQ-------IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
L+ +L KE I+ ++ QT EL + ++ E K + H+ +
Sbjct: 433 LSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLE-EENKAKNALGHALQSSRHDCDLLRE 491
Query: 534 QESPNGISYQDLQQ-------EIMDLKMKL-LDVVHRNEELSEI---LAKKDQELEQQDK 582
Q +LQ+ E+ + K D + R EEL E LA++ Q+ E+Q +
Sbjct: 492 QYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVE 551
Query: 583 NSRGQ-ARVIKIREELINVLKN--KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ A + K ++ L +++ + E++ LAA L+ + R D+V + K +E
Sbjct: 552 AVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA---LDKKQRNFDKVLAEWKTKCEE 608
Query: 640 IQ-ELFATLENKQQQIHRLEKI 660
Q EL A+L+ + L K+
Sbjct: 609 SQAELEASLKESRSLSTELFKL 630
Score = 70.1 bits (164), Expect = 2e-11
Identities = 109/504 (21%), Positives = 215/504 (42%), Gaps = 34/504 (6%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 49 ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 108
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL +EK E+ + + A+ DK L
Sbjct: 109 KVEKEKHATENKVKNLTEELSGLD-ETIAKLT-REKKALQEAHQQALDDLQAEEDKVNSL 166
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ ++ + ++ +Q ++ V LE RKL LK + + L + L E
Sbjct: 167 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLD-ER 225
Query: 358 LECKQ----QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
L+ K Q++ ++ Q ++ +K+ + ++E E + E + +TE + D
Sbjct: 226 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 285
Query: 414 RNAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC-KREKES 471
+EEL ++ E + +L +RE + + +E E V T K+ +S
Sbjct: 286 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS 345
Query: 472 ENKIGIQ---QKLAAELLNKEEIIGKMQI----QTRELIKNIKLNEQKVIQ-YEQYVRDL 523
++G Q + + L KE+ K++I + E + K N +K+ + E + +
Sbjct: 346 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 405
Query: 524 QAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLD---VVHRNEELSEILAKKDQE-- 576
+ N I Q S + ++ Q LQ E +L +L + +V + + ++ +E
Sbjct: 406 RGKNEEI---QRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 462
Query: 577 --LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA 634
LE+++K ++ ++L+ + E+ A LQ+ L V + +
Sbjct: 463 RQLEEENKAKNALGHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY- 521
Query: 635 AKADEIQELFATLENKQQQIHRLE 658
+ D IQ E K++ RL+
Sbjct: 522 -ETDAIQRTEELEEAKKKLAQRLQ 544
Score = 64.1 bits (149), Expect = 2e-09
Identities = 84/421 (19%), Positives = 183/421 (43%), Gaps = 37/421 (8%)
Query: 256 EEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE 315
++ + EL + + ++EKL T + + +V + L +AE
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC----------- 51
Query: 316 DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI 375
DQ + + QLEA+ +++ E + E ++L ++ L+ E E K+ I+ L +
Sbjct: 52 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 111
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA---KIIELEKSKP 432
++ + K +E + + +L + + + A+++LQA K+ L K+K
Sbjct: 112 KEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKS 171
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE--LLNKEE 490
+ E DL + L+ K+ LRV ++ KR+ E + K+ + L E +E
Sbjct: 172 KLEQQVE---DLESSLEQEKK-LRV---DLERNKRKLEGDLKLAQESILDLENDKQQLDE 224
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
+ K + +L ++ + +Q+++ +++LQA + E+ + +Q
Sbjct: 225 RLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR-S 283
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET---- 606
D +L ++ R EE + + Q + N + +A +K+R +L E
Sbjct: 284 DYARELEELSERLEEAGGVTS------TQIELNKKREAEFLKLRRDLEEATLQHEAMVAT 337
Query: 607 ---EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLA 663
+ + +A L + +++ R+ ++ K+ + EI +L +++E+ + LEKI
Sbjct: 338 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRT 397
Query: 664 L 664
L
Sbjct: 398 L 398
Score = 59.7 bits (138), Expect = 3e-08
Identities = 120/565 (21%), Positives = 245/565 (43%), Gaps = 59/565 (10%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LE+ D + +E++ K K NL ++ + + LS + E
Sbjct: 357 QRVKQKLEKEKSEFKLEIDDLSSSMESVSK-SKANL----EKICRTLEDQLSEARGKNEE 411
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAV----GEALVREVAKLRQDVETRNV 237
+ +L EL TQ +LS R E+ ++++ +A ++ +L++ +E N
Sbjct: 412 IQRSLSELTTQKSRLQTEAGELS-RQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK 470
Query: 238 MIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV-AKMDKQ 296
+ + S + L +R + +EE+ K ++ L+ S++ Q R + ++
Sbjct: 471 AKNALGHALQSSRHDCDL--LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 528
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE 356
E E + L ++ E+Q + A K ++ L+ GEV + +R + A
Sbjct: 529 TEELEEAKKKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQ-GEVEDLMVDVERANSLAA 586
Query: 357 VLECKQQ-IEKLTVQHKSAIQQ----LEEDLKQT----------KRALQE---QCEITKR 398
L+ KQ+ +K+ + K+ ++ LE LK++ K A +E Q E KR
Sbjct: 587 ALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKR 646
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL---WAELQATKETL 455
E + E E+ D I E I ELEKS+ +L + +I L AE E
Sbjct: 647 E---NKNLEQEIADLTEQIAENGKTIHELEKSRKQIEL-EKADIQLALEEAEAALEHEEA 702
Query: 456 RVTEDEVTTCKREKESENKIGIQQKLAAEL-LNKEEIIGKMQIQTRELIK--NIKLNEQK 512
++ ++ + + E + KI + + +L N + + MQ ++ N + +K
Sbjct: 703 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRRANEAIRLKK 762
Query: 513 VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK 572
++ + ++Q + AN Q + + +Q ++ D ++ L D + E+L E LA
Sbjct: 763 KMEGDLNEIEIQLSH---ANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 819
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ-QDLEHRMRIVDEVNK 631
++ + + QA V ++R L ++TE++R+LA + D R++++ N
Sbjct: 820 VER------RANLLQAEVEELRATL------EQTERARKLAEQELLDSNERVQLLHTQNT 867
Query: 632 QIAAKADEIQELFATLENKQQQIHR 656
+ +++ L+++ + R
Sbjct: 868 SLIHTKKKLETDLMQLQSEVEDASR 892
Score = 58.8 bits (136), Expect = 6e-08
Identities = 96/451 (21%), Positives = 192/451 (42%), Gaps = 30/451 (6%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+G +++ +L+ +E I+ R R+++E ++ + EL EE + +L +
Sbjct: 246 LGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRS--DYAREL-EELSERLEEAGGV 302
Query: 277 TTTESQLRQTRN-RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
T+T+ +L + R K+ + L EA ++ T++ S + + +++++
Sbjct: 303 TSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQK 362
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
L+ + I S V + K +EK+ ++ QL E + + + E+
Sbjct: 363 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKIC---RTLEDQLSEARGKNEEIQRSLSEL 419
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKET 454
T + K R +TE + +EE ++ + +L +SK TE + L E +A
Sbjct: 420 TTQ----KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 475
Query: 455 LRVTEDEVTTC-----KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ C + E+E E K +Q+ L+ N E + + +T + + +L
Sbjct: 476 GHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA--NSEVAQWRTKYETDAIQRTEELE 533
Query: 510 EQKVIQYEQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E K + Q ++D + + A C + Q LQ E+ DL ++DV N L+
Sbjct: 534 EAKK-KLAQRLQDSEEQVEAVNAKCASLEK--TKQRLQGEVEDL---MVDVERANS-LAA 586
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK + ++ + + + + + EL LK + S EL L+ E + ++
Sbjct: 587 ALDKKQRNFDKV--LAEWKTKCEESQAELEASLKESRS-LSTELFKLKNAYEEALDQLET 643
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
V ++ EI +L + + IH LEK
Sbjct: 644 VKRENKNLEQEIADLTEQIAENGKTIHELEK 674
Score = 58.4 bits (135), Expect = 8e-08
Identities = 102/451 (22%), Positives = 192/451 (42%), Gaps = 46/451 (10%)
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN---RVAKMDKQLREAEAS 303
S++E +L+E R E K A +E L E+ R+ +N +A + +Q+ E +
Sbjct: 609 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 668
Query: 304 ITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
I L + K +E + ++ LE A A E K + +L Q + + ++ E +
Sbjct: 669 IHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQL-ELTQVKSEIDRKIAEKDE 727
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR-EIELKERTETELQDS-RNAIEEL 420
+IE+L ++ ++ ++ L R E + K+ E +L E E +L + R A E L
Sbjct: 728 EIEQLKRNYQRTVETMQSALDAEVRRANEAIRLKKKMEGDLNE-IEIQLSHANRQAAETL 786
Query: 421 Q-AKIIE--LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ + ++ L+ ++ + D + DL +L + + + EV + E +
Sbjct: 787 KHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA-- 844
Query: 478 QQKLAA-ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI---ANC 533
+KLA ELL+ E + + Q LI K E ++Q + V D R A
Sbjct: 845 -RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 903
Query: 534 QESPNGISYQDLQQEI----------MDLKMKLLDVVHRNEELSEILAK--KDQ------ 575
+ + ++L++E +L+ + D+ HR +E ++ K K Q
Sbjct: 904 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 963
Query: 576 -------ELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
ELE + K + + ++ E + L + E + + LQ DL ++++ +
Sbjct: 964 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQ-DLVDKLQVKVK 1022
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
K+ A +ADE T K Q H LE+
Sbjct: 1023 SYKRQAEEADEQANAHLTKFRKAQ--HELEE 1051
Score = 48.8 bits (111), Expect = 6e-05
Identities = 64/258 (24%), Positives = 112/258 (43%), Gaps = 20/258 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRA--CHERRT-LIAVGEALVREVAKLRQDVETRNV 237
EL L + + + A + D ++R H + T LI + L ++ +L+ +VE
Sbjct: 833 ELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVE---- 888
Query: 238 MIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL 297
D R+ R+ E K + EE + L + L QT V + +L
Sbjct: 889 --DASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRL 943
Query: 298 REAEA-SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSL 353
EAE ++ ++ LE + R+ E +LE +K ES+K E +L Q +
Sbjct: 944 DEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEED 1003
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ VL + ++KL V+ KS +Q EE +Q L + K + EL+E E +
Sbjct: 1004 RKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHL---TKFRKAQHELEE-AEERADIA 1059
Query: 414 RNAIEELQAKIIELEKSK 431
+ + +L+AK + S+
Sbjct: 1060 ESQVNKLRAKTRDFTSSR 1077
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 86.6 bits (205), Expect = 3e-16
Identities = 86/407 (21%), Positives = 194/407 (47%), Gaps = 28/407 (6%)
Query: 257 EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED 316
E++H+LD+ + + +T ++LR+ +N + ++ +Q+ E + I +L + L
Sbjct: 478 ELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNL----EALLQ 533
Query: 317 QSRQKEVQLEARARKLRESLKTGEVTTS---QLIQQRDSLQAEVLECKQQIEKLTVQHKS 373
+S++ LE L ++ GE T+ QL ++ +LQ EV + + ++ + HK
Sbjct: 534 KSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQ 593
Query: 374 AIQQLEEDLKQTKRALQE-QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKP 432
A + L + +++ K L+ Q + E + E ++L +S+ + +L +I K+K
Sbjct: 594 AQENLHDQVQEQKAHLRAAQDRVLSLETSVNE-LNSQLNESKEKVSQLDIQI----KAK- 647
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE-NKIGIQ-QKLAAELLNKEE 490
TE + A A + L+ D ++K E NKI Q ++ A+L +K+E
Sbjct: 648 -----TELLLSAEAAKTAQRADLQNHLDTAQNALQDKHQELNKITTQLDQVTAKLQDKQE 702
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
+++ +E + EQK + E ++ L+A + + +E + QDLQQ+
Sbjct: 703 HCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQ----ALQDLQQQRQ 758
Query: 551 ---DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETE 607
DL+++ ++ + E EI++ +L+++ + + + +EE +LK
Sbjct: 759 LNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFET 818
Query: 608 QSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
S+E ++L +R++ +++ + + + +T+++K ++
Sbjct: 819 LSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKV 865
Score = 76.2 bits (179), Expect = 4e-13
Identities = 108/484 (22%), Positives = 223/484 (46%), Gaps = 60/484 (12%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
+ EL T +D ++ V+D K + E G+A + ++ K ++++ +L
Sbjct: 852 MTELST-VKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELK---------HQL 901
Query: 246 RSESENT-KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+ + ENT K +E++ L++E+ A +K +L + + QL Q +N + + +K+ ++
Sbjct: 902 QVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQ----- 956
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
L G + L+ S QK+ Q+EA L+ LK + Q + + LQ ++ + Q++
Sbjct: 957 --LQGNINELKQSSEQKKKQIEA----LQGELK---IAVLQKTELENKLQQQLTQAAQEL 1007
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQE-QCEITKREIELKERTETELQDSRNAIEELQAK 423
K I L+ + ++++ ++ Q + RE EL T +L+ + Q
Sbjct: 1008 ----AAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELL-ATRQDLKSVEEKLSLAQED 1062
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
+I N + L EL+ K TL E + K+E++ + + Q +
Sbjct: 1063 LISNRNQIGNQN-------KLIQELKTAKATL-----EQDSAKKEQQLQERCKALQDIQK 1110
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN----RTIANCQESPNG 539
E KE+ + + + E I+ IK ++K I + +L++H + I N +++
Sbjct: 1111 EKSLKEKELVNEKSKLAE-IEEIKCRQEKEI--TKLNEELKSHKLESIKEITNLKDAKQL 1167
Query: 540 ISYQDLQ-QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
+ Q L+ Q D ++ RN+++ + KK++E +++ + +I+E+ +
Sbjct: 1168 LIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEV 1227
Query: 599 NVLKNKETEQ--SRELAALQQDL-------EHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ K++E E + ++ AL ++L + R V E+ KQ EI L AT++N
Sbjct: 1228 GMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQN 1287
Query: 650 KQQQ 653
Q +
Sbjct: 1288 NQDE 1291
Score = 72.9 bits (171), Expect = 3e-12
Identities = 93/465 (20%), Positives = 204/465 (43%), Gaps = 27/465 (5%)
Query: 214 LIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALE--EMRHELDEERTAKLA 271
L+ A ++ + + ++ +T N I ++++L + A E +++ + DEER+ + A
Sbjct: 129 LVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREA 188
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQL--REAEASITSLTGTVKMLEDQSRQKEVQLEARA 329
++K+T +L + + + +L R + L + ++ ++ E +
Sbjct: 189 AEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERES 248
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL 389
KL++ K E Q S +A + + + ++ K + + +Q+L++ LK + L
Sbjct: 249 EKLKDESKKFE-------SQYASSEATISQLRSELSKGPQEVRVYVQELQK-LKSSVNEL 300
Query: 390 QEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQ 449
++ + + KE+ T+L++ N E + K I+ + + D + +E
Sbjct: 301 TQKNQTLTENLLKKEQDYTKLEEKHNE-ESVSKKNIQATLHQKDLDCQQLQSRLSASETS 359
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ + ++E T K ++E Q L AE ++ + + +L I
Sbjct: 360 LHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQL 419
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK-------LLDVVHR 562
K+++ E+ + +AH R Q S + D +Q++ DL++K L + V
Sbjct: 420 HSKLLETERQLG--EAHGRLKEQRQLSSEKL--MDKEQQVADLQLKLSRLEEQLKEKVTN 475
Query: 563 NEELSEILAK-KDQELEQQDKNSRGQARVIKIREELINVLK--NKETEQSRELAALQQDL 619
+ EL L K K Q EQQ A++ + + +L VL+ ++ ++ + L AL Q
Sbjct: 476 STELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKS 535
Query: 620 EHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
+ + ++++ + + AK + A L Q++ H L+ V L
Sbjct: 536 KENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQL 580
Score = 70.1 bits (164), Expect = 2e-11
Identities = 119/583 (20%), Positives = 237/583 (40%), Gaps = 61/583 (10%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q D + + +L DE+ E+ +Y + T++Q +++ LS+ +
Sbjct: 234 QTLMDNMTLERERESEKLKDESKKFES--QYASSEATISQLRSE------LSKGPQEVRV 285
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
L++LK+ + L++ + + + E E + T + +
Sbjct: 286 YVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLD 345
Query: 242 IRELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
++L+S S + +L + EL E+ A +KE+L+ E++ + + ++ +Q E
Sbjct: 346 CQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEK 405
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
E L + L + + E QL +L+E + QQ LQ ++
Sbjct: 406 EQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRL 465
Query: 361 KQQI-EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
++Q+ EK+T +L+ L +TK+ QEQ + + + +L+ I E
Sbjct: 466 EEQLKEKVTNS-----TELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGE 520
Query: 420 LQAKIIELE----KSKPNPDLPTEREIDLWAELQA----------TKETLRVTEDEVT-- 463
KI LE KSK N L + DL+A++QA +E +DEVT
Sbjct: 521 KDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQL 580
Query: 464 --TCKREKES-----ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
K + ES EN Q+ A L ++ + ++ EL + +++KV Q
Sbjct: 581 TENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQL 640
Query: 517 EQYVRD-----LQAHNRTIANCQESPNGI-----SYQDLQQEIMDLKMKLLDVV------ 560
+ ++ L A A + N + + QD QE+ + +L V
Sbjct: 641 DIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKHQELNKITTQLDQVTAKLQDK 700
Query: 561 --HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE--TEQSRELAALQ 616
H ++ S + K++ L + K + ++ K+ + + V +KE + ++ L
Sbjct: 701 QEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLN 760
Query: 617 QDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
DLE R E++KQ+ + + + L+ K + + +++
Sbjct: 761 TDLELR---ATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQ 800
Score = 69.3 bits (162), Expect = 4e-11
Identities = 92/409 (22%), Positives = 189/409 (46%), Gaps = 45/409 (11%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
+L G + ELK +E + L + L +++ + Q++ I
Sbjct: 956 QLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKIS 1015
Query: 241 EIRELRSESENT-KALEE----MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++ +S+ T K L+ EL R +++EKL+ + L RN++ +K
Sbjct: 1016 VLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNK 1075
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSL-Q 354
++E + + +L E S +KE QL+ R + L++ K + +L+ ++ L +
Sbjct: 1076 LIQELKTAKATL-------EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAE 1128
Query: 355 AEVLECKQ--QIEKLTVQHKS-AIQQLEE--DLK-------QTKRALQEQCEITKREIEL 402
E ++C+Q +I KL + KS ++ ++E +LK Q K LQ + + K +E
Sbjct: 1129 IEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQ 1188
Query: 403 KERTETELQDS-RNAIEELQAKIIELEKSKPNPDLPTEREIDLWA-ELQATKETLRVT-- 458
++R + L+D + EEL+ + IE E +K + ++ E+E+ + E K T+++T
Sbjct: 1189 EKRNQQILKDQVKKEEEELKKEFIEKE-AKLHSEI-KEKEVGMKKHEENEAKLTMQITAL 1246
Query: 459 EDEVTTCKRE-KESENKIGIQQK----LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ + T K+E + S+ ++ +K L E+ E + Q + R L++ E ++
Sbjct: 1247 NENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEI 1306
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ + V +LQ ++ N + Q+L +E L++K ++R
Sbjct: 1307 EKLQTKVLELQ---------RKLDNTTAVQELGRENQSLQIKHTQALNR 1346
Score = 65.7 bits (153), Expect = 5e-10
Identities = 93/487 (19%), Positives = 218/487 (44%), Gaps = 34/487 (6%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID-EIRELRSE 248
K Q + + T D +++ + E+ ++E + +E + ++ +I++L ++
Sbjct: 679 KHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEAD 738
Query: 249 SENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
S KA +E +L ++R ++ + T QL + V+ L++ ++ S+
Sbjct: 739 SLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESI 798
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLR---ESLKTGEVTTSQLIQ----QRDSLQAEVLEC 360
+ E++ + + E +++ + E L TT +Q ++++L E+
Sbjct: 799 KQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTV 858
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
K ++ K++ K++ + E++ ++ K A+ ++ K ELK + + +++++ +EL
Sbjct: 859 KDKLSKVSDSLKNSKSEFEKENQKGKAAI---LDLEKTCKELKHQLQVQMENTLKEQKEL 915
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ K +E EK E L EL + +E L + + T + EKE + G +
Sbjct: 916 K-KSLEKEK---------EASHQLKLELNSMQEQL--IQAQNTLKQNEKEEQQLQGNINE 963
Query: 481 LAAELLNKEEIIGKMQIQTR-ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQES--P 537
L K++ I +Q + + +++ +L + Q Q ++L A I+ Q +
Sbjct: 964 LKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEK 1023
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ +++ LQ + + +LL + + E L+ ++L ++N G + +L
Sbjct: 1024 SQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDL-ISNRNQIGN------QNKL 1076
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
I LK + ++ A +Q L+ R + + ++ K+ + K E+ + L ++ R
Sbjct: 1077 IQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQ 1136
Query: 658 EKIVLAL 664
EK + L
Sbjct: 1137 EKEITKL 1143
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 85.8 bits (203), Expect = 5e-16
Identities = 116/541 (21%), Positives = 242/541 (44%), Gaps = 47/541 (8%)
Query: 146 IENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTV-TDLS 204
IE + + L VNQ + + + LS +L L LK Q + + +
Sbjct: 523 IEEMNEKTLEKLDVNQTELES-LSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMD 581
Query: 205 KRACHERR---TLIAVGEALVREVAK-LRQDVETRNVMIDE----IRELRSESENTKA-L 255
++ H ++ ++I E ++ K L+ + +++ E ++E ++ EN +A +
Sbjct: 582 EQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 641
Query: 256 EEMRHELDEERTAKLAIKEKL-TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKML 314
+ EL ++ +AKL + + + T Q + ++A++ ++L + E LT V +
Sbjct: 642 KRSEGEL-QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV 700
Query: 315 EDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECK--------QQIEK 366
E Q + +L+A ++++ ++ E S++ Q+ SL +V E K +Q ++
Sbjct: 701 EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL-TQVYESKLEDGNKEQEQTKQ 759
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNAIEELQAKII 425
+ V+ ++ I Q+ E K+ L ++ + I L E ET+ ++ +E+++ K
Sbjct: 760 ILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAK 819
Query: 426 ELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAA-E 484
E++++ L ++E L EL+ T L E + E N GI ++ E
Sbjct: 820 EMQETLKKKLL--DQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLE 877
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQD 544
KE+I ++ REL I + E+K+ Q + ++++ I Q+
Sbjct: 878 TNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHE--------------IQLQE 923
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK 604
+QE+ +LK K+L EE+++ + +E +QD +K + +N L
Sbjct: 924 KEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQD 983
Query: 605 ETEQSRELAALQQDLEHRMR---IVDE--VNKQIAAKAD--EIQELFATLENKQQQIHRL 657
ET+ L L+ DL ++ + E V ++ A+ D ++ EL + L+ ++ L
Sbjct: 984 ETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSL 1043
Query: 658 E 658
+
Sbjct: 1044 K 1044
Score = 67.7 bits (158), Expect = 1e-10
Identities = 104/467 (22%), Positives = 206/467 (44%), Gaps = 49/467 (10%)
Query: 212 RTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKL 270
+TL + + + R+ L++ ET ++ L SE E + L+E EL++ + +
Sbjct: 134 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 193
Query: 271 AIKEKLTTTE-------SQLRQTRNRV-AKMDKQLREA----EASITSLTGTVKMLEDQS 318
A K KL T QL Q + V A+ +Q+ E E I L +K + Q
Sbjct: 194 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 253
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL 378
+ Q E R E L+ T + + R L+AE+ E + IEK + + + ++QQ
Sbjct: 254 EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE 313
Query: 379 EEDLKQ-----TKRALQEQC---------EITKREIELKERTET---ELQDS-RNAIEEL 420
+KQ K++ +EQ E+ ++E EL ++ +T E Q+ + A+E+
Sbjct: 314 LSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS 373
Query: 421 QAKIIELEKSKPNPDLPTEREIDLW--AELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
Q++ +++ + K + E++L A L ++ LR + E T R + E + ++
Sbjct: 374 QSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAET-YRTRILELESSLE 432
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKL------NEQKVIQYEQ---YVRDLQAHNRT 529
+ L +++ ++ + + K I + E + ++++Q + +LQ +
Sbjct: 433 KSLQENENQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWAEELQVLKQQ 492
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQAR 589
E Q+ + + D +++ H E + L K D + + S +
Sbjct: 493 YQTEMEKLREKCEQEKETLLKD--KEIIFQAHIEEMNEKTLEKLDVNQTELESLSSELSE 550
Query: 590 VIKIR---EELINVLKNKETEQSREL-AALQQDLEHRMRIVDEVNKQ 632
V+K R EE ++VLK++ + +EL A + + H + VD + K+
Sbjct: 551 VLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKE 597
Score = 63.3 bits (147), Expect = 3e-09
Identities = 92/442 (20%), Positives = 197/442 (44%), Gaps = 38/442 (8%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRH--ELDEERTAKLA-IKEKLTTTESQLRQTR 287
++E+ N ++ + + + E+ + +++++H EL EE+ ++ +EK+ T E+Q+ +
Sbjct: 1395 EIESLNEVLKNYNQ-QKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMK 1453
Query: 288 NRVAKMDKQLREAEASITSLTGTVKMLED----QSRQKEVQLEARARKLRESLKTGEVTT 343
+ K+L S+ S +K LED +S K +L+ +A + ++K +
Sbjct: 1454 AELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIK--KQLL 1511
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
SQ+ ++ + + ++ + + + LEE LK + + E + + +
Sbjct: 1512 SQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVA 1571
Query: 404 ERTETELQDSRNAIEE-LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEV 462
TE E DS+ +++ + KI L+++ TE+E L Q +ET V+
Sbjct: 1572 AYTEQEEADSQGCVQKTYEEKISVLQRNL------TEKEKLLQRVGQEKEET--VSSHFE 1623
Query: 463 TTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
C+ + E I ++ A+ + +IG +Q + E K L + ++ E +
Sbjct: 1624 MRCQYQ---ERLIKLEH-AEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNN 1679
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD--VVHRNE----ELSEILAK--KD 574
+QA + + ++L +I++ K+K LD +V + E E+ E+ +K K
Sbjct: 1680 IQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKL 1739
Query: 575 QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELA---ALQQDLEHRMRIVDEVNK 631
Q L+Q D G+ + ++ EE Q + L+ A DLE ++ + +
Sbjct: 1740 QALQQMD----GRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQ 1795
Query: 632 QIAAKADEIQELFATLENKQQQ 653
++ + +Q+ L + QQ
Sbjct: 1796 KLGKEIVRLQKDLRMLRKEHQQ 1817
Score = 61.7 bits (143), Expect = 9e-09
Identities = 105/523 (20%), Positives = 237/523 (45%), Gaps = 53/523 (10%)
Query: 138 ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV 197
+LLD+ ++ ++ L+ + Q + +LE +++ N G + A+ L+T ++ +
Sbjct: 828 KLLDQEAKLKKELENTALELSQKEKQFNAKMLE-MAQANSAG--ISDAVSRLETNQKEQI 884
Query: 198 NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEE 257
++T++ +R E +I++ E KL Q E + EI E++ + E + + E
Sbjct: 885 ESLTEVHRR---ELNDVISIWEK------KLNQQAEE----LQEIHEIQLQ-EKEQEVAE 930
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
++ ++ K + +++T + + + + ++ +QL++ A + SL +D+
Sbjct: 931 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLA------QDE 984
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA--- 374
++ K LE L +SLK QL++ + + AE E K+++ +LT + K+
Sbjct: 985 TKLK-AHLEKLEVDLNKSLKENTFLQEQLVELK--MLAE--EDKRKVSELTSKLKTTDEE 1039
Query: 375 IQQLEEDLKQTKRALQEQC-EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN 433
Q L+ +++ ++L+++ E K EL + + + + +E ++I + SK N
Sbjct: 1040 FQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTN 1099
Query: 434 PDLPTEREIDLWAELQATKETLRV---TEDEVTTCKRE-KESENKIGIQQKLAAELLNKE 489
L R KE L + T E+ R+ E +N + I + A L ++
Sbjct: 1100 AIL--SRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEK 1157
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI 549
E IK++K + + ++ ++ ++ + + A+ +ES ++L + I
Sbjct: 1158 E----------NQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENI 1207
Query: 550 MDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
+ + ++ + E+S L+K+ +L Q +NS + +E I+ L+ + E+
Sbjct: 1208 NAVTLMKEELKEKKVEISS-LSKQLTDLNVQLQNSIS----LSEKEAAISSLRKQYDEEK 1262
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
EL QDL ++ + + + D+ F+ + K Q
Sbjct: 1263 CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQ 1305
Score = 59.3 bits (137), Expect = 5e-08
Identities = 106/565 (18%), Positives = 254/565 (44%), Gaps = 58/565 (10%)
Query: 139 LLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVN 198
+ +T+ IE++ + K N +D ++++ L + + G E ++E + + N
Sbjct: 1389 ITQKTIEIESLNEVLK-NYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLEN 1447
Query: 199 TVTDLSKRACHERRTLIAVG---EALVREVAKLRQDVETRNVMIDEIRELRSESENTKAL 255
V + +++ L V ++ E+ L +E+ + ++ EL+ ++E A
Sbjct: 1448 QVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAA--KLAELKRKAEQKIAA 1505
Query: 256 --EEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS---LTG 309
+++ +++E E K + L+ ++L++ V ++++L+ E+S + +
Sbjct: 1506 IKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPR 1565
Query: 310 TVKMLEDQSRQKEVQLEARARKLRE---SLKTGEVTTSQLIQQRDSLQAEV-------LE 359
+ K + + Q+E + +K E S+ +T + + QR + E +
Sbjct: 1566 SAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMR 1625
Query: 360 CKQQIEKLTVQH--------KSAIQQLEEDLKQTKR------ALQEQCEITKREIELKER 405
C+ Q + ++H +S I L+E+L++ + A + E K I+ K+
Sbjct: 1626 CQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQN 1685
Query: 406 TETELQDSRNAIEE--LQAKIIELEKSKPNPDLPTEREIDL--WAELQATKETLRVTEDE 461
E D + ++E L +I+E + + + L ++E+ EL + E L+ +
Sbjct: 1686 LENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM 1745
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQK----VI 514
K + E ++K + L+ + +++ M+ Q +L + + +QK ++
Sbjct: 1746 DGRNKPTELLEENT--EEKSKSHLV-QPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIV 1802
Query: 515 QYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEILAK 572
+ ++ +R L+ H + + ++ + + ++QE DL++K + + E + LA+
Sbjct: 1803 RLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQ 1862
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR----IVDE 628
K+QELE K + +A+ ++ EL+ + + + +++A DL+ + I+D
Sbjct: 1863 KEQELEMTIKETINKAQ--EVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDA 1920
Query: 629 VNKQIAAKADEIQELFATLENKQQQ 653
+++ AK ++Q L+ K QQ
Sbjct: 1921 REEEMTAKVRDLQTQLEELQKKYQQ 1945
Score = 53.2 bits (122), Expect = 3e-06
Identities = 104/493 (21%), Positives = 224/493 (45%), Gaps = 55/493 (11%)
Query: 185 ALRELKTQAE----DAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
AL EL+ Q + ++ N + DL + A R ++ + +L + + + + V +
Sbjct: 391 ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENENQSKDLAVHL- 449
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAI-KEKLTTTESQLRQTRNRVAKMDKQLRE 299
E + + E T +E+ + EL+ + + A+ E+L + Q + ++ + +Q +E
Sbjct: 450 EAEKNKHNKEITVMVEKHKTELESLKHQQDALWAEELQVLKQQYQTEMEKLREKCEQEKE 509
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ +E+ + + +L+ +L ESL + S++++ R L+ E+
Sbjct: 510 TLLKDKEIIFQAH-IEEMNEKTLEKLDVNQTEL-ESLSS---ELSEVLKARHKLEEELSV 564
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK-ERTETELQDSRNAIE 418
K Q +K+ Q+LE + + K Q+Q + +E E+ +RTE L+D N +E
Sbjct: 565 LKDQTDKMK-------QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 617
Query: 419 -----------ELQAKIIELE---KSKPNPDLPTEREIDLWAELQ-ATKETLRVTEDEVT 463
E QA + LE K ++D++ Q AT E + E+++
Sbjct: 618 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 677
Query: 464 TCKR---EKESENKIGIQQKLAAELLNKEEIIGKM---QIQTRELIKNIKLNEQKVIQYE 517
++ + E+E +I + +++A K+++ ++ +IQ ++L++ + E++ + E
Sbjct: 678 QLQQKLLDLETE-RILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQL---EKQNSEME 733
Query: 518 QYVRDL-QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKD-- 574
Q V+ L Q + + + + +++E M L+M+ ++ AK+D
Sbjct: 734 QKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 793
Query: 575 ----QELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEV 629
+E E + KN + +K + +E+ LK K +Q A L+++LE+ + +
Sbjct: 794 HILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQE---AKLKKELENTALELSQK 850
Query: 630 NKQIAAKADEIQE 642
KQ AK E+ +
Sbjct: 851 EKQFNAKMLEMAQ 863
Score = 52.0 bits (119), Expect = 7e-06
Identities = 84/387 (21%), Positives = 171/387 (44%), Gaps = 34/387 (8%)
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
+KM+K+ E + S T + LED QK +++E+ L+ + ++ +L+Q+
Sbjct: 1362 SKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKL 1421
Query: 351 DSLQAEVLECK----QQIEKLTVQHKSAIQQLEEDLKQTKRALQE-QCEITKREIELK-- 403
Q E+ E K ++ E+ + ++ + ++ +L+ K+ L+ + +E ELK
Sbjct: 1422 QHFQ-ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1480
Query: 404 -ERTETE----LQDSRNAIEELQAKI-----IELEKSKPNPDLPTEREI-DLWAELQATK 452
+R E+E L + + E+ A I ++E+ + TE + +L +LQ +
Sbjct: 1481 EDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERE 1540
Query: 453 ETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEI--IGKMQIQTRELIKNIKLN- 509
+ + E+++ + + + + K A +EE G +Q E I ++ N
Sbjct: 1541 REVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNL 1600
Query: 510 --EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNEEL 566
++K++Q ++ + CQ I + + ++ D M + H EEL
Sbjct: 1601 TEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSM----IGHLQEEL 1656
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN-KETEQSRELAALQQDLEHRMRI 625
E KK + Q G I+ ++ L NV + ++T Q +EL Q LE +++
Sbjct: 1657 EE-KNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTC--QILEQKIKE 1713
Query: 626 VDE-VNKQIAAKADEIQELFATLENKQ 651
+D + +Q E++EL + E Q
Sbjct: 1714 LDSCLVRQKEVHRVEMEELTSKYEKLQ 1740
Score = 50.4 bits (115), Expect = 2e-05
Identities = 101/488 (20%), Positives = 216/488 (44%), Gaps = 46/488 (9%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
+E+ E+ V T L++ + + A +L ++ KL+ +E + +D + L+
Sbjct: 947 KEITWLKEEGVKQDTTLNELQ-EQLKQKSAHVNSLAQDETKLKAHLE--KLEVDLNKSLK 1003
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
+ + L E++ +E++ + KL TT+ + + ++ K +K L +
Sbjct: 1004 ENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1063
Query: 307 LTGTVKM-LEDQSRQKEVQLEARARKLRE--SLKTGEVTTS-QLIQQRDSLQAEVL---- 358
L+ + + L+ ++ E LEA+ +L S KT + + Q R + E L
Sbjct: 1064 LSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKT 1123
Query: 359 ----ECKQQIEKLTVQHKS---AIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
E + Q+ +LT + + + QQ L++ + ++ + + KE + E
Sbjct: 1124 CTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGG 1183
Query: 412 DSRNAIEELQAKIIELEKS-KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
+ + A E ++ I +L+K N + T + EL+ K + ++T +
Sbjct: 1184 NQQQAASEKESCITQLKKELSENINAVTLMK----EELKEKKVEISSLSKQLTDLN--VQ 1237
Query: 471 SENKIGIQQKLAA-ELLNKEEIIGKMQI--QTREL-IKNIKLNEQKVIQYEQYVRDLQAH 526
+N I + +K AA L K+ K ++ Q ++L K L+++K+ EQ D ++
Sbjct: 1238 LQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQV--DDWSN 1295
Query: 527 NRTIANCQESPNGISYQDLQQEI-MDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
+ + +Q+ +E+ + L++K + ++E+++ L K +EL+QQ+K
Sbjct: 1296 KFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQIN--LLK--EELDQQNK--- 1348
Query: 586 GQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
R ++ E+ + E ++S L+ +L+ + + E+ I K EI+ L
Sbjct: 1349 ---RFDCLKGEMEDDKSKMEKKESN----LETELKSQTARIMELEDHITQKTIEIESLNE 1401
Query: 646 TLENKQQQ 653
L+N QQ
Sbjct: 1402 VLKNYNQQ 1409
Score = 44.0 bits (99), Expect = 0.002
Identities = 55/293 (18%), Positives = 125/293 (42%), Gaps = 23/293 (7%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
A + L+ +D T+ + + + + LVR+ R ++E ++++
Sbjct: 1682 AKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQA 1741
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
L+ K E + +E+ + L + L+ E+Q ++A +++ ++ I
Sbjct: 1742 LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEI 1801
Query: 305 TSLTGTVKMLE--------------DQSRQKEVQLEARARKLRESLKTGEVT---TSQLI 347
L ++ML DQ R+++++ E +L+ + ++ +QL
Sbjct: 1802 VRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLA 1861
Query: 348 QQRDSLQAEVLEC---KQQIE-KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
Q+ L+ + E Q++E +L H+ QL + + + L+ + + ++ +
Sbjct: 1862 QKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAR 1921
Query: 404 ERTET-ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
E T +++D + +EELQ K + + + NP ++L +L A K TL
Sbjct: 1922 EEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQL-AQKTTL 1973
Score = 41.9 bits (94), Expect = 0.007
Identities = 52/258 (20%), Positives = 117/258 (45%), Gaps = 34/258 (13%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
+++ND F+L GA RE + ++ V DL ++ L E+ K D
Sbjct: 1778 AQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQEL---------EILKKEYDQ 1828
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
E + E +L E ++ L+++ E + +LA KE+ E +++T N+ +
Sbjct: 1829 EREEKIKQEQEDL--ELKHNSTLKQLMREFN----TQLAQKEQ--ELEMTIKETINKAQE 1880
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
++ +L E+ T+ L + +K+ L+ A++ E L E +
Sbjct: 1881 VEAELLESHQEETN------QLLKKIAEKDDDLKRTAKRYEEILDARE----------EE 1924
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
+ A+V + + Q+E+L +++ ++Q E ++ Q ++ ++ + + ++ + Q+
Sbjct: 1925 MTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISD-SKLKEQE 1983
Query: 413 SRNAIEELQAKIIELEKS 430
R I L+ ++ + EK+
Sbjct: 1984 FREQIHNLEDRLKKYEKN 2001
Score = 34.3 bits (75), Expect = 1.5
Identities = 78/376 (20%), Positives = 154/376 (40%), Gaps = 28/376 (7%)
Query: 200 VTDLSKRACHERRTLIAVGEALVREVA---KLRQDVETRNVMIDEIRELRSESENTKA-L 255
++ L + + + L VG+ V+ ++R + R + ++ + E ++ L
Sbjct: 1593 ISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHL 1652
Query: 256 EEMRHELDEERTAKLA--IKEKLTTTESQLRQTRNRVAK-MDKQLREAEASITSLTGTVK 312
+E E +++ + +A ++++ Q +Q V + K L+E E + L +K
Sbjct: 1653 QEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIK 1712
Query: 313 MLED-QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
L+ RQKEV R E L T + Q +QQ D ++ E+ + H
Sbjct: 1713 ELDSCLVRQKEVH-----RVEMEEL-TSKYEKLQALQQMDGRNKPTELLEENTEEKSKSH 1766
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ-DSRNAIEELQAKIIELEKS 430
+L +++ L+ + +RE + + LQ D R +E Q ELE
Sbjct: 1767 LVQ-PKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEIL 1822
Query: 431 KPNPDLPTEREIDLWAELQATKE--TLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
K D E +I E K TL+ E T +KE E ++ I++ + +
Sbjct: 1823 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVE 1882
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE 548
E++ Q +T +L+K K+ + + ++ I + +E +DLQ +
Sbjct: 1883 AELLESHQEETNQLLK-------KIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQ 1935
Query: 549 IMDLKMKLLDVVHRNE 564
+ +L+ K + + E
Sbjct: 1936 LEELQKKYQQKLEQEE 1951
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 85.4 bits (202), Expect = 6e-16
Identities = 84/407 (20%), Positives = 196/407 (48%), Gaps = 28/407 (6%)
Query: 257 EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED 316
E++H+LD+ + + +T ++LR+ +N + ++ +Q+ + + I +L + L
Sbjct: 478 ELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNL----EALLQ 533
Query: 317 QSRQKEVQLEARARKLRESLKTGEVTTS---QLIQQRDSLQAEVLECKQQIEKLTVQHKS 373
+S++ LE L ++ GE T+ QL ++ +LQ +V + ++++ + HK
Sbjct: 534 KSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQ 593
Query: 374 AIQQLEEDLKQTKRALQE-QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKP 432
A + L + +++ K L+ Q + E + E ++L +S+ + +L +I K+K
Sbjct: 594 AQENLHDQVQEQKAHLRAAQDRVLSLETSVNE-LNSQLNESKEKVSQLDIQI----KAK- 647
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE-NKIGIQ-QKLAAELLNKEE 490
TE + A A + L+ D ++K+ E NKI Q ++ A+L +K+E
Sbjct: 648 -----TELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQE 702
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
+++ +E + EQK + E ++ L+A + + +E + QDLQQ+
Sbjct: 703 HCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQ----ALQDLQQQRQ 758
Query: 551 ---DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETE 607
DL+++ ++ + E EI++ +L+++ + + + +EE +LK
Sbjct: 759 LNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFET 818
Query: 608 QSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
S+E ++L +R++ +++ + + + +T+++K ++
Sbjct: 819 LSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKV 865
Score = 77.4 bits (182), Expect = 2e-13
Identities = 105/520 (20%), Positives = 229/520 (44%), Gaps = 32/520 (6%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
+ EL T +D ++ V+D K + E G+A + ++ K ++++ +L
Sbjct: 852 MTELST-VKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELK---------HQL 901
Query: 246 RSESENT-KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+ + ENT K +E++ L++E+ A +K +L + + QL Q +N + + +K+ ++
Sbjct: 902 QVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQ----- 956
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
L G + L+ S QK+ Q+EA +L+ ++ ++L QQ E+ K++I
Sbjct: 957 --LQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKI 1014
Query: 365 EKLTVQHKSA---IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
L ++ + +QL+ D + L + K E + +L +RN I
Sbjct: 1015 SVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQN 1074
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAE----LQATKETLRVTEDEVTTCKREKESENKIGI 477
I EL+ +K + + ++ E LQ ++ + E E+ K + +I
Sbjct: 1075 KLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKC 1134
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+Q+ LN+E + ++++ + I N+K +Q +IQ + ++ +A + A QE
Sbjct: 1135 RQEKEITKLNEE--LKSHKLESIKEITNLKDAKQLLIQQKLELQG-KADSLKAAVEQEKR 1191
Query: 538 NGISYQD-LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREE 596
N +D +++E +LK + ++ + +L + +K+ +++ ++N I E
Sbjct: 1192 NQQILKDQVKKEEEELKKEFIE---KEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNE 1248
Query: 597 LINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ +K + R ++ L++ + + + + DE + L + +I +
Sbjct: 1249 NLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEK 1308
Query: 657 LEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRK 696
L+ VL L + +L+ + LNRK
Sbjct: 1309 LQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALNRK 1348
Score = 76.6 bits (180), Expect = 3e-13
Identities = 112/474 (23%), Positives = 212/474 (44%), Gaps = 51/474 (10%)
Query: 224 EVAKLRQDVETRNVMIDEIR----ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
+V LRQ+V+ + E + EL+ E E + L++ + D T A +L +
Sbjct: 84 DVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSA---ELQSL 140
Query: 280 ESQLR--QTRNRVAKMDKQLREAEAS-ITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
E QL QT N K K L E +A+ + + +K D+ R E + +L E L
Sbjct: 141 EQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEEL 200
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
E T Q ++ + LQ +E ++K VQ ++ + + + ++ L+++C+
Sbjct: 201 NK-EATVIQDLKT-ELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKL 258
Query: 397 KREIELKERTETELQDS-RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ + E T ++L+ +E+ + EL+K K + + T++ L L ++
Sbjct: 259 QSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDY 318
Query: 456 RVTEDEVTTCKREKESENKIGIQ----------QKLAAELLNKEEIIGKMQIQTRELIKN 505
E+ K +ES +K IQ Q+L + L E + ++ ++ E +
Sbjct: 319 TKLEE-----KHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEA 373
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV------ 559
+ ++++ + E + L+A + + +E Q LQ EI L KLL+
Sbjct: 374 TQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQ-LQSEINQLHSKLLETERQLGE 432
Query: 560 VH-RNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN---------KETEQS 609
H R +E ++ ++K + EQQ + Q ++ ++ E+L + N K +Q
Sbjct: 433 AHGRLKEQRQLSSEKLMDKEQQVADL--QLKLSRLEEQLKEKVTNSTELQHQLDKTKQQH 490
Query: 610 RELAALQQDLEHRMRI----VDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+E ALQQ ++R +++V +QI K +IQ L A L+ ++ I LEK
Sbjct: 491 QEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEK 544
Score = 70.1 bits (164), Expect = 2e-11
Identities = 97/462 (20%), Positives = 199/462 (43%), Gaps = 49/462 (10%)
Query: 241 EIRELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+ ++L+S S + +L + EL E+ A +KE+L+ E++ + + ++ +Q E
Sbjct: 345 DCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREE 404
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
E L + L + + E QL +L+E + QQ LQ ++
Sbjct: 405 KEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSR 464
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQ--TKRALQEQCEITKREIELK-ERTETELQDSRNA 416
++Q+++ QL++ +Q ++ALQ+ RE + E+ ++ D
Sbjct: 465 LEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQK 524
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLWAELQA----------TKETLRVTEDEVT--T 464
I+ L+A L+KSK N L + DL+A++QA +E +++VT T
Sbjct: 525 IQNLEAL---LQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLT 581
Query: 465 CKREKESENKIGIQQKL-------AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
K + +SE+ Q+ L A L ++ + ++ EL + +++KV Q +
Sbjct: 582 EKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLD 641
Query: 518 QYVRD-----LQAHNRTIANCQESPNGI-----SYQDLQQEIMDLKMKLLDVV------- 560
++ L A A + N + + QD QQE+ + +L V
Sbjct: 642 IQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQ 701
Query: 561 -HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE--TEQSRELAALQQ 617
H ++ S + K++ L + K + ++ K+ + + V +KE + ++ L
Sbjct: 702 EHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNT 761
Query: 618 DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
DLE R E++KQ+ + + + L+ K + + +++
Sbjct: 762 DLELR---ATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQ 800
Score = 70.1 bits (164), Expect = 2e-11
Identities = 89/383 (23%), Positives = 178/383 (46%), Gaps = 37/383 (9%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
+L G + ELK +E + L + L +++ + Q++ I
Sbjct: 956 QLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKIS 1015
Query: 241 EIRELRSESENT-KALEE----MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++ +S+ T K L+ EL R +++EKL+ + L RN++ +K
Sbjct: 1016 VLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNK 1075
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSL-Q 354
++E + + +L E S +KE QL+ R + L++ K + +L+ ++ L +
Sbjct: 1076 LIQELKTAKATL-------EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAE 1128
Query: 355 AEVLECKQ--QIEKLTVQHKS-AIQQLEE--DLK-------QTKRALQEQCEITKREIEL 402
E ++C+Q +I KL + KS ++ ++E +LK Q K LQ + + K +E
Sbjct: 1129 IEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQ 1188
Query: 403 KERTETELQDS-RNAIEELQAKIIELEKSKPNPDLPTEREIDLWA-ELQATKETLRVT-- 458
++R + L+D + EEL+ + IE E +K + ++ E+E+ + E K T+++T
Sbjct: 1189 EKRNQQILKDQVKKEEEELKKEFIEKE-AKLHSEI-KEKEVGMKKHEENEAKLTMQITAL 1246
Query: 459 EDEVTTCKRE-KESENKIGIQQK----LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ + T K+E + S+ ++ +K L E+ E + Q + R L++ E ++
Sbjct: 1247 NENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEI 1306
Query: 514 IQYEQYVRDLQAH-NRTIANCQE 535
+ + V +LQ + T A QE
Sbjct: 1307 EKLQTKVLELQRKLDNTTAAVQE 1329
Score = 66.1 bits (154), Expect = 4e-10
Identities = 93/487 (19%), Positives = 218/487 (44%), Gaps = 34/487 (6%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID-EIRELRSE 248
K Q + + T D +++ + E+ ++E + +E + ++ +I++L ++
Sbjct: 679 KQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEAD 738
Query: 249 SENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
S KA +E +L ++R ++ + T QL + V+ L++ ++ S+
Sbjct: 739 SLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESI 798
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLR---ESLKTGEVTTSQLIQ----QRDSLQAEVLEC 360
+ E++ + + E +++ + E L TT +Q ++++L E+
Sbjct: 799 KQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTV 858
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
K ++ K++ K++ + E++ ++ K A+ ++ K ELK + + +++++ +EL
Sbjct: 859 KDKLSKVSDSLKNSKSEFEKENQKGKAAI---LDLEKTCKELKHQLQVQMENTLKEQKEL 915
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ K +E EK E L EL + +E L + + T + EKE + G +
Sbjct: 916 K-KSLEKEK---------EASHQLKLELNSMQEQL--IQAQNTLKQNEKEEQQLQGNINE 963
Query: 481 LAAELLNKEEIIGKMQIQTR-ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQES--P 537
L K++ I +Q + + +++ +L + Q Q ++L A I+ Q +
Sbjct: 964 LKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEK 1023
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ +++ LQ + + +LL + + E L+ ++L ++N G + +L
Sbjct: 1024 SQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDL-ISNRNQIGN------QNKL 1076
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
I LK + ++ A +Q L+ R + + ++ K+ + K E+ + L ++ R
Sbjct: 1077 IQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQ 1136
Query: 658 EKIVLAL 664
EK + L
Sbjct: 1137 EKEITKL 1143
Score = 49.6 bits (113), Expect = 4e-05
Identities = 62/282 (21%), Positives = 126/282 (44%), Gaps = 29/282 (10%)
Query: 134 ENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGF-ELCGALRELKTQ 192
E L L E + I N + N + + +T LE S +Q E C AL++++ +
Sbjct: 1053 EEKLSLAQEDL-ISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKE 1111
Query: 193 A----EDAVNT---VTDLSKRACHERRTLIAVGEAL----VREVAKLRQDVETRNVMIDE 241
++ VN + ++ + C + + + + E L + + ++ + + ++I +
Sbjct: 1112 KSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQ 1171
Query: 242 IRELRSESENTKAL--EEMRHEL-------DEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
EL+ ++++ KA +E R++ EE K EK S++++ + K
Sbjct: 1172 KLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKK 1231
Query: 293 MDKQLREAEASITSLT---GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
++ + IT+L GTVK S+++ +LE + LR + E T +
Sbjct: 1232 HEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDE 1291
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE 391
R +L L+ + +IEKL ++ + +L+ L T A+QE
Sbjct: 1292 RRALLERCLKGEGEIEKL----QTKVLELQRKLDNTTAAVQE 1329
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 85.4 bits (202), Expect = 6e-16
Identities = 89/398 (22%), Positives = 179/398 (44%), Gaps = 12/398 (3%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
+E++ E +L + R + + +L E E + L L++Q Q E +L A A +L
Sbjct: 130 EEEMMAKEEELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQL-QAETELCAEAEEL 188
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE- 391
R L + ++ ++ E E Q ++ + + IQ+LEE L++ + A Q+
Sbjct: 189 RARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKL 248
Query: 392 QCEITKREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
Q E E +LK+ E + + + +N + K++E ++ +L E E
Sbjct: 249 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 308
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
K +T+ E + EK+ + ++KL + + + I ++Q Q EL + E
Sbjct: 309 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 368
Query: 511 QKVIQYEQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
+++ V + A N + +E + IS +LQ+++ + + +L E
Sbjct: 369 EELQAALARVEEEAAQKNMALKKIRELESQIS--ELQEDLESERASRNKAEKQKRDLGEE 426
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQQDLEHRMRIVDE 628
L ELE ++ Q + RE+ +N+LK E E A +Q+ + + V+E
Sbjct: 427 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 486
Query: 629 VNKQI----AAKADEIQELFATLENKQQQIHRLEKIVL 662
+ +Q+ KA+ +++ TLEN++ ++ K++L
Sbjct: 487 LAEQLEQTKRVKAN-LEKAKQTLENERGELANEVKVLL 523
Score = 79.0 bits (186), Expect = 5e-14
Identities = 112/501 (22%), Positives = 214/501 (42%), Gaps = 48/501 (9%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA----LVREVAKLRQDVETRN 236
ELC EL+ + + ++ CH+ + E L E K++Q+++
Sbjct: 180 ELCAEAEELRARLTAKKQELEEI----CHDLEARVEEEEERYQHLQAEKKKMQQNIQELE 235
Query: 237 VMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++E R + + K E + +L+EE+ + ++++ + + +R+A+
Sbjct: 236 EQLEEEESARQKLQLEKVTTEAKLKKLEEEQ---IILEDQNCKLAKEKKLLEDRIAEFTT 292
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDS 352
L E E SL E E +L ++ +E KT E ++ L Q
Sbjct: 293 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 352
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
LQA++ E K Q+ K + ++A+ ++EE+ Q AL++ E+ + EL+E E+E +
Sbjct: 353 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE-RA 411
Query: 413 SRNAIEELQAKI-IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES 471
SRN E+ + + ELE L TE E D A +E E EV K+ E
Sbjct: 412 SRNKAEKQKRDLGEELEA------LKTELE-DTLDSTAAQQELRSKREQEVNILKKTLEE 464
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
E K + E+ K + + E K +K N +K Q + R A+ +
Sbjct: 465 EAK--THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 522
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ + ++ ++ +L++K + E + LA K +L+ + N G
Sbjct: 523 LQGGRDSEHKRKKVEAQLQELQVKF----NEGERVRTELADKVTKLQVELDNVTG----- 573
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAK----ADEIQELF 644
L++ +K ++ +++ +AL+ L+ ++ E N+Q ++ K DE
Sbjct: 574 -----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 628
Query: 645 ATLENKQQQI-HRLEKIVLAL 664
LE ++++ H LEK + L
Sbjct: 629 EQLEEEEEEAKHNLEKQIATL 649
Score = 59.7 bits (138), Expect = 3e-08
Identities = 101/447 (22%), Positives = 206/447 (46%), Gaps = 46/447 (10%)
Query: 230 QDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN- 288
++ E ++ + +I L ++ + K ++M + TA+ +K KL L Q
Sbjct: 634 EEEEAKHNLEKQIATLHAQVADMK--KKMEDSVGCLETAE-EVKRKLQKDLEGLSQRHEE 690
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQ 348
+VA DK L + + + + + D RQ LE + +K + L + +++ +
Sbjct: 691 KVAAYDK-LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAE 749
Query: 349 QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTET 408
+RD +AE E ++ + L S + LEE A++++ E+ + L ++ T
Sbjct: 750 ERDRAEAEARE--KETKAL-----SLARALEE-------AMEQKAELER----LNKQFRT 791
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED-----EVT 463
E++D ++ +++ + ELEKSK + E ++ +L+ ++ L+ TED EV
Sbjct: 792 EMEDLMSSKDDVGKSVHELEKSKRALEQQVE---EMKTQLEELEDELQATEDAKLRLEVN 848
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI---QYEQYV 520
+ + E + + + + E K++++ +++ EL K V + E +
Sbjct: 849 LQAMKAQFERDLQGRDEQSEE--KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDL 906
Query: 521 RDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQ 580
+DL+AH + AN + LQ ++ D M+ LD + E EILA Q E +
Sbjct: 907 KDLEAHIDS-ANKNRDEAIKQLRKLQAQMKDC-MRELDDTRASRE--EILA---QAKENE 959
Query: 581 DKNSRGQARVIKIREELINVLKNK-ETEQSR-ELAALQQDLEHRMRIVDEVNKQIAAKAD 638
K +A +I+++EEL + K + +Q R ELA + + + E +++ A+
Sbjct: 960 KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIA 1019
Query: 639 EIQELFATLENKQQQIH-RLEKIVLAL 664
+++E + + I+ RL+K L +
Sbjct: 1020 QLEEELEEEQGNTELINDRLKKANLQI 1046
Score = 57.6 bits (133), Expect = 1e-07
Identities = 94/537 (17%), Positives = 231/537 (43%), Gaps = 48/537 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
++E++ + AV + + ++ + L + L E +L +V+ V++ R+
Sbjct: 473 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVK---VLLQGGRDS 529
Query: 246 RSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMD----KQLREA 300
+ + +A L+E++ + +E + + +K+T + +L +++ D K ++
Sbjct: 530 EHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDF 589
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
A + L T ++L++++RQK + L + +++ + + R+ L+ E E
Sbjct: 590 SALESQLQDTQELLQEENRQK-LSLSTKLKQVEDEKNSF----------REQLEEEEEEA 638
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
K +EK I L + K+ +++ + E+K + + +L+ EE
Sbjct: 639 KHNLEK-------QIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEK 691
Query: 421 QAKIIELEKSKPN---------PDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES 471
A +LEK+K DL +R+ E + K + E++ + K +E
Sbjct: 692 VAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEER 751
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ ++ + L+ + + Q EL +LN+Q + E + +++
Sbjct: 752 DRAEAEAREKETKALSLARALEEAMEQKAEL---ERLNKQFRTEMEDLMSSKDDVGKSVH 808
Query: 532 NCQESPNGISYQ--DLQQEIMDLKMKLL---DVVHRNE-ELSEILAKKDQELEQQDKNSR 585
++S + Q +++ ++ +L+ +L D R E L + A+ +++L+ +D+ S
Sbjct: 809 ELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSE 868
Query: 586 GQAR-VIKIREELINVLKNKETEQSRELAA---LQQDLEHRMRIVDEVNKQIAAKADEIQ 641
+ + +++ E+ L+++ ++S +AA L+ DL+ +D NK +++
Sbjct: 869 EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLR 928
Query: 642 ELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+L A +++ +++ + ++ L+ ELAA K +
Sbjct: 929 KLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQ 985
Score = 53.6 bits (123), Expect = 2e-06
Identities = 63/303 (20%), Positives = 135/303 (44%), Gaps = 18/303 (5%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
+ ++ L + Q + L + + E+ + + K+ +I + E L
Sbjct: 922 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 981
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
RQ + R+ + DEI S + ALEE R E R A+L +E+L +
Sbjct: 982 AKRQAQQERDELADEIAN--SSGKGALALEEKRRL--EARIAQL--EEELEEEQGNTELI 1035
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT-SQ 345
+R+ K + Q+ + A + G + E+ +RQ QLE + ++L+ L+ E T S+
Sbjct: 1036 NDRLKKANLQIDQINADLNLERGHAQKNEN-ARQ---QLERQNKELKVKLQEMEGTVKSK 1091
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+L+A++ + ++Q++ T + ++A +Q+ K+ K L + + + + K++
Sbjct: 1092 YKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQ 1151
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC 465
+ + +++L+ ++ E E+ + + L EL+ ET EV++
Sbjct: 1152 ADK----ASTRLKQLKRQLEEAEEEAQRANASRRK---LQRELEDATETADAMNREVSSL 1204
Query: 466 KRE 468
K +
Sbjct: 1205 KNK 1207
Score = 52.4 bits (120), Expect = 5e-06
Identities = 46/213 (21%), Positives = 91/213 (42%), Gaps = 13/213 (6%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
++ +E R ++E EL E NT+ + + L + I L ++ N
Sbjct: 1011 KRRLEARIAQLEE--ELEEEQGNTELIND---RLKKANLQIDQINADLNLERGHAQKNEN 1065
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL----KTGEVTTS 344
++++Q +E + + + GTVK + + LEA+ +L E L K +
Sbjct: 1066 ARQQLERQNKELKVKLQEMEGTVK---SKYKASITALEAKIAQLEEQLDNETKERQAACK 1122
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
Q+ + L+ +L+ + + Q+K + LKQ KR L+E E +R +
Sbjct: 1123 QVRRTEKKLKDVLLQVDDE-RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRR 1181
Query: 405 RTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
+ + EL+D+ + + ++ L+ DLP
Sbjct: 1182 KLQRELEDATETADAMNREVSSLKNKLRRGDLP 1214
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 85.0 bits (201), Expect = 8e-16
Identities = 89/398 (22%), Positives = 179/398 (44%), Gaps = 12/398 (3%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
+E++ E +L + R + + +L E E + L L++Q Q E +L A A +L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEEL 902
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE- 391
R L + ++ ++ E E Q ++ + + IQ+LEE L++ + A Q+
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 392 QCEITKREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
Q E E +LK+ E + + + +N + K++E ++ +L E E
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
K +T+ E + EK+ + ++KL + + + I ++Q Q EL + E
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 511 QKVIQYEQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
+++ V + A N + +E + IS +LQ+++ + + +L E
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQIS--ELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQQDLEHRMRIVDE 628
L ELE ++ Q + RE+ +N+LK E E A +Q+ + + V+E
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1200
Query: 629 VNKQI----AAKADEIQELFATLENKQQQIHRLEKIVL 662
+ +Q+ KA+ +++ TLEN++ ++ K++L
Sbjct: 1201 LAEQLEQTKRVKAN-LEKAKQTLENERGELANEVKVLL 1237
Score = 83.0 bits (196), Expect = 3e-15
Identities = 112/500 (22%), Positives = 214/500 (42%), Gaps = 47/500 (9%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA----LVREVAKLRQDVETRN 236
ELC EL+ + + ++ CH+ + E L E K++Q+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEI----CHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949
Query: 237 VMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++E R + + K E + +L+EE+ + ++++ + + +R+A+
Sbjct: 950 EQLEEEESARQKLQLEKVTTEAKLKKLEEEQ---IILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDS 352
L E E SL E E +L ++ +E KT E ++ L Q
Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
LQA++ E K Q+ K + ++A+ ++EE+ Q AL++ E+ + EL+E E+E +
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE-RA 1125
Query: 413 SRNAIEELQAKI-IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES 471
SRN E+ + + ELE L TE E D A +E E EV K+ E
Sbjct: 1126 SRNKAEKQKRDLGEELEA------LKTELE-DTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
E K + E+ K + + E K +K N +K Q + R A+ +
Sbjct: 1179 EAK--THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ + + ++ ++ +L++K + E + LA K +L+ + N G
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQELQVKF----NEGERVRTELADKVTKLQVELDNVTG----- 1287
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAK----ADEIQELF 644
L++ +K ++ +++ +AL+ L+ ++ E N+Q ++ K DE
Sbjct: 1288 -----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 645 ATLENKQQQIHRLEKIVLAL 664
LE +++ H LEK + L
Sbjct: 1343 EQLEEEEEAKHNLEKQIATL 1362
Score = 63.7 bits (148), Expect = 2e-09
Identities = 115/522 (22%), Positives = 234/522 (44%), Gaps = 50/522 (9%)
Query: 155 TNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTL 214
T L V D G LS+ + + +L L++Q +D + + +++ L
Sbjct: 1276 TKLQVELDNVTG----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL 1331
Query: 215 IAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKE 274
V + +L ++ E ++ + +I L ++ + K ++M + TA+ +K
Sbjct: 1332 KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK--KKMEDSVGCLETAE-EVKR 1388
Query: 275 KLTTTESQLRQTRN-RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLR 333
KL L Q +VA DK L + + + + + D RQ LE + +K
Sbjct: 1389 KLQKDLEGLSQRHEEKVAAYDK-LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFD 1447
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
+ L + +++ ++RD +AE E ++ + L S + LEE A++++
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEAEARE--KETKAL-----SLARALEE-------AMEQKA 1493
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE 453
E+ + L ++ TE++D ++ +++ + ELEKSK + E ++ +L+ ++
Sbjct: 1494 ELER----LNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVE---EMKTQLEELED 1546
Query: 454 TLRVTED-----EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
L+ TED EV + + E + + + + E K++++ +++ EL K
Sbjct: 1547 ELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE--KKKQLVRQVREMEAELEDERKQ 1604
Query: 509 NEQKVI---QYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
V + E ++DL+AH + AN + LQ ++ D M+ LD + E
Sbjct: 1605 RSMAVAARKKLEMDLKDLEAHIDS-ANKNRDEAIKQLRKLQAQMKDC-MRELDDTRASRE 1662
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSR-ELAALQQDLEHRM 623
EILA Q E + K +A +I+++EEL + K + +Q R ELA + +
Sbjct: 1663 --EILA---QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQIH-RLEKIVLAL 664
+ E +++ A+ +++E + + I+ RL+K L +
Sbjct: 1718 ALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759
Score = 54.0 bits (124), Expect = 2e-06
Identities = 47/213 (22%), Positives = 92/213 (43%), Gaps = 13/213 (6%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
++ +E R ++E EL E NT+ + + L + I L S ++ N
Sbjct: 1724 KRRLEARIAQLEE--ELEEEQGNTELIND---RLKKANLQIDQINTDLNLERSHAQKNEN 1778
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL----KTGEVTTS 344
++++Q +E + + + GTVK + + LEA+ +L E L K +
Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVK---SKYKASITALEAKIAQLEEQLDNETKERQAACK 1835
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
Q+ + L+ +L+ + + Q+K + LKQ KR L+E E +R +
Sbjct: 1836 QVRRTEKKLKDVLLQVDDE-RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRR 1894
Query: 405 RTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
+ + EL+D+ + + ++ L+ DLP
Sbjct: 1895 KLQRELEDATETADAMNREVSSLKNKLRRGDLP 1927
Score = 51.2 bits (117), Expect = 1e-05
Identities = 61/303 (20%), Positives = 134/303 (44%), Gaps = 18/303 (5%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
+ ++ L + Q + L + + E+ + + K+ +I + E L
Sbjct: 1635 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
RQ + R+ + DEI S + ALEE R E R A+L +E+L +
Sbjct: 1695 AKRQAQQERDELADEIAN--SSGKGALALEEKRRL--EARIAQL--EEELEEEQGNTELI 1748
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT-SQ 345
+R+ K + Q+ + + +L + + +RQ QLE + ++L+ L+ E T S+
Sbjct: 1749 NDRLKKANLQIDQINTDL-NLERSHAQKNENARQ---QLERQNKELKVKLQEMEGTVKSK 1804
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+L+A++ + ++Q++ T + ++A +Q+ K+ K L + + + + K++
Sbjct: 1805 YKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQ 1864
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC 465
+ + +++L+ ++ E E+ + + L EL+ ET EV++
Sbjct: 1865 ADK----ASTRLKQLKRQLEEAEEEAQRANASRRK---LQRELEDATETADAMNREVSSL 1917
Query: 466 KRE 468
K +
Sbjct: 1918 KNK 1920
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 85.0 bits (201), Expect = 8e-16
Identities = 89/398 (22%), Positives = 179/398 (44%), Gaps = 12/398 (3%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
+E++ E +L + R + + +L E E + L L++Q Q E +L A A +L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEEL 902
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE- 391
R L + ++ ++ E E Q ++ + + IQ+LEE L++ + A Q+
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 392 QCEITKREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
Q E E +LK+ E + + + +N + K++E ++ +L E E
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
K +T+ E + EK+ + ++KL + + + I ++Q Q EL + E
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 511 QKVIQYEQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
+++ V + A N + +E + IS +LQ+++ + + +L E
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQIS--ELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQQDLEHRMRIVDE 628
L ELE ++ Q + RE+ +N+LK E E A +Q+ + + V+E
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1200
Query: 629 VNKQI----AAKADEIQELFATLENKQQQIHRLEKIVL 662
+ +Q+ KA+ +++ TLEN++ ++ K++L
Sbjct: 1201 LAEQLEQTKRVKAN-LEKAKQTLENERGELANEVKVLL 1237
Score = 83.0 bits (196), Expect = 3e-15
Identities = 112/500 (22%), Positives = 214/500 (42%), Gaps = 47/500 (9%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA----LVREVAKLRQDVETRN 236
ELC EL+ + + ++ CH+ + E L E K++Q+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEI----CHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949
Query: 237 VMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++E R + + K E + +L+EE+ + ++++ + + +R+A+
Sbjct: 950 EQLEEEESARQKLQLEKVTTEAKLKKLEEEQ---IILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDS 352
L E E SL E E +L ++ +E KT E ++ L Q
Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
LQA++ E K Q+ K + ++A+ ++EE+ Q AL++ E+ + EL+E E+E +
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE-RA 1125
Query: 413 SRNAIEELQAKI-IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES 471
SRN E+ + + ELE L TE E D A +E E EV K+ E
Sbjct: 1126 SRNKAEKQKRDLGEELEA------LKTELE-DTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
E K + E+ K + + E K +K N +K Q + R A+ +
Sbjct: 1179 EAK--THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ + + ++ ++ +L++K + E + LA K +L+ + N G
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQELQVKF----NEGERVRTELADKVTKLQVELDNVTG----- 1287
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAK----ADEIQELF 644
L++ +K ++ +++ +AL+ L+ ++ E N+Q ++ K DE
Sbjct: 1288 -----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 645 ATLENKQQQIHRLEKIVLAL 664
LE +++ H LEK + L
Sbjct: 1343 EQLEEEEEAKHNLEKQIATL 1362
Score = 63.7 bits (148), Expect = 2e-09
Identities = 115/522 (22%), Positives = 234/522 (44%), Gaps = 50/522 (9%)
Query: 155 TNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTL 214
T L V D G LS+ + + +L L++Q +D + + +++ L
Sbjct: 1276 TKLQVELDNVTG----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL 1331
Query: 215 IAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKE 274
V + +L ++ E ++ + +I L ++ + K ++M + TA+ +K
Sbjct: 1332 KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK--KKMEDSVGCLETAE-EVKR 1388
Query: 275 KLTTTESQLRQTRN-RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLR 333
KL L Q +VA DK L + + + + + D RQ LE + +K
Sbjct: 1389 KLQKDLEGLSQRHEEKVAAYDK-LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFD 1447
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
+ L + +++ ++RD +AE E ++ + L S + LEE A++++
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEAEARE--KETKAL-----SLARALEE-------AMEQKA 1493
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE 453
E+ + L ++ TE++D ++ +++ + ELEKSK + E ++ +L+ ++
Sbjct: 1494 ELER----LNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVE---EMKTQLEELED 1546
Query: 454 TLRVTED-----EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
L+ TED EV + + E + + + + E K++++ +++ EL K
Sbjct: 1547 ELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE--KKKQLVRQVREMEAELEDERKQ 1604
Query: 509 NEQKVI---QYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
V + E ++DL+AH + AN + LQ ++ D M+ LD + E
Sbjct: 1605 RSMAVAARKKLEMDLKDLEAHIDS-ANKNRDEAIKQLRKLQAQMKDC-MRELDDTRASRE 1662
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSR-ELAALQQDLEHRM 623
EILA Q E + K +A +I+++EEL + K + +Q R ELA + +
Sbjct: 1663 --EILA---QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQIH-RLEKIVLAL 664
+ E +++ A+ +++E + + I+ RL+K L +
Sbjct: 1718 ALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759
Score = 54.0 bits (124), Expect = 2e-06
Identities = 47/213 (22%), Positives = 92/213 (43%), Gaps = 13/213 (6%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
++ +E R ++E EL E NT+ + + L + I L S ++ N
Sbjct: 1724 KRRLEARIAQLEE--ELEEEQGNTELIND---RLKKANLQIDQINTDLNLERSHAQKNEN 1778
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL----KTGEVTTS 344
++++Q +E + + + GTVK + + LEA+ +L E L K +
Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVK---SKYKASITALEAKIAQLEEQLDNETKERQAACK 1835
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
Q+ + L+ +L+ + + Q+K + LKQ KR L+E E +R +
Sbjct: 1836 QVRRTEKKLKDVLLQVDDE-RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRR 1894
Query: 405 RTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
+ + EL+D+ + + ++ L+ DLP
Sbjct: 1895 KLQRELEDATETADAMNREVSSLKNKLRRGDLP 1927
Score = 51.2 bits (117), Expect = 1e-05
Identities = 61/303 (20%), Positives = 134/303 (44%), Gaps = 18/303 (5%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
+ ++ L + Q + L + + E+ + + K+ +I + E L
Sbjct: 1635 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
RQ + R+ + DEI S + ALEE R E R A+L +E+L +
Sbjct: 1695 AKRQAQQERDELADEIAN--SSGKGALALEEKRRL--EARIAQL--EEELEEEQGNTELI 1748
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT-SQ 345
+R+ K + Q+ + + +L + + +RQ QLE + ++L+ L+ E T S+
Sbjct: 1749 NDRLKKANLQIDQINTDL-NLERSHAQKNENARQ---QLERQNKELKVKLQEMEGTVKSK 1804
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+L+A++ + ++Q++ T + ++A +Q+ K+ K L + + + + K++
Sbjct: 1805 YKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQ 1864
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC 465
+ + +++L+ ++ E E+ + + L EL+ ET EV++
Sbjct: 1865 ADK----ASTRLKQLKRQLEEAEEEAQRANASRRK---LQRELEDATETADAMNREVSSL 1917
Query: 466 KRE 468
K +
Sbjct: 1918 KNK 1920
>BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for
IMAGE:5563109) protein.
Length = 1374
Score = 85.0 bits (201), Expect = 8e-16
Identities = 89/398 (22%), Positives = 179/398 (44%), Gaps = 12/398 (3%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
+E++ E +L + R + + +L E E + L L++Q Q E +L A A +L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEEL 902
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE- 391
R L + ++ ++ E E Q ++ + + IQ+LEE L++ + A Q+
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 392 QCEITKREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
Q E E +LK+ E + + + +N + K++E ++ +L E E
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
K +T+ E + EK+ + ++KL + + + I ++Q Q EL + E
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 511 QKVIQYEQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
+++ V + A N + +E + IS +LQ+++ + + +L E
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQIS--ELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQQDLEHRMRIVDE 628
L ELE ++ Q + RE+ +N+LK E E A +Q+ + + V+E
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1200
Query: 629 VNKQI----AAKADEIQELFATLENKQQQIHRLEKIVL 662
+ +Q+ KA+ +++ TLEN++ ++ K++L
Sbjct: 1201 LAEQLEQTKRVKAN-LEKAKQTLENERGELANEVKVLL 1237
Score = 83.0 bits (196), Expect = 3e-15
Identities = 112/500 (22%), Positives = 214/500 (42%), Gaps = 47/500 (9%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA----LVREVAKLRQDVETRN 236
ELC EL+ + + ++ CH+ + E L E K++Q+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEI----CHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949
Query: 237 VMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++E R + + K E + +L+EE+ + ++++ + + +R+A+
Sbjct: 950 EQLEEEESARQKLQLEKVTTEAKLKKLEEEQ---IILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDS 352
L E E SL E E +L ++ +E KT E ++ L Q
Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
LQA++ E K Q+ K + ++A+ ++EE+ Q AL++ E+ + EL+E E+E +
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE-RA 1125
Query: 413 SRNAIEELQAKI-IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES 471
SRN E+ + + ELE L TE E D A +E E EV K+ E
Sbjct: 1126 SRNKAEKQKRDLGEELEA------LKTELE-DTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
E K + E+ K + + E K +K N +K Q + R A+ +
Sbjct: 1179 EAK--THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ + + ++ ++ +L++K + E + LA K +L+ + N G
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQELQVKF----NEGERVRTELADKVTKLQVELDNVTG----- 1287
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAK----ADEIQELF 644
L++ +K ++ +++ +AL+ L+ ++ E N+Q ++ K DE
Sbjct: 1288 -----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 645 ATLENKQQQIHRLEKIVLAL 664
LE +++ H LEK + L
Sbjct: 1343 EQLEEEEEAKHNLEKQIATL 1362
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 85.0 bits (201), Expect = 8e-16
Identities = 89/398 (22%), Positives = 179/398 (44%), Gaps = 12/398 (3%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
+E++ E +L + R + + +L E E + L L++Q Q E +L A A +L
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEEL 902
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE- 391
R L + ++ ++ E E Q ++ + + IQ+LEE L++ + A Q+
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 392 QCEITKREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
Q E E +LK+ E + + + +N + K++E ++ +L E E
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
K +T+ E + EK+ + ++KL + + + I ++Q Q EL + E
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 511 QKVIQYEQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
+++ V + A N + +E + IS +LQ+++ + + +L E
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQIS--ELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQQDLEHRMRIVDE 628
L ELE ++ Q + RE+ +N+LK E E A +Q+ + + V+E
Sbjct: 1141 LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE 1200
Query: 629 VNKQI----AAKADEIQELFATLENKQQQIHRLEKIVL 662
+ +Q+ KA+ +++ TLEN++ ++ K++L
Sbjct: 1201 LAEQLEQTKRVKAN-LEKAKQTLENERGELANEVKVLL 1237
Score = 83.0 bits (196), Expect = 3e-15
Identities = 112/500 (22%), Positives = 214/500 (42%), Gaps = 47/500 (9%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA----LVREVAKLRQDVETRN 236
ELC EL+ + + ++ CH+ + E L E K++Q+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEI----CHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949
Query: 237 VMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++E R + + K E + +L+EE+ + ++++ + + +R+A+
Sbjct: 950 EQLEEEESARQKLQLEKVTTEAKLKKLEEEQ---IILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDS 352
L E E SL E E +L ++ +E KT E ++ L Q
Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
LQA++ E K Q+ K + ++A+ ++EE+ Q AL++ E+ + EL+E E+E +
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE-RA 1125
Query: 413 SRNAIEELQAKI-IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES 471
SRN E+ + + ELE L TE E D A +E E EV K+ E
Sbjct: 1126 SRNKAEKQKRDLGEELEA------LKTELE-DTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
E K + E+ K + + E K +K N +K Q + R A+ +
Sbjct: 1179 EAK--THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ + + ++ ++ +L++K + E + LA K +L+ + N G
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQELQVKF----NEGERVRTELADKVTKLQVELDNVTG----- 1287
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAK----ADEIQELF 644
L++ +K ++ +++ +AL+ L+ ++ E N+Q ++ K DE
Sbjct: 1288 -----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 645 ATLENKQQQIHRLEKIVLAL 664
LE +++ H LEK + L
Sbjct: 1343 EQLEEEEEAKHNLEKQIATL 1362
Score = 63.7 bits (148), Expect = 2e-09
Identities = 115/522 (22%), Positives = 234/522 (44%), Gaps = 50/522 (9%)
Query: 155 TNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTL 214
T L V D G LS+ + + +L L++Q +D + + +++ L
Sbjct: 1276 TKLQVELDNVTG----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL 1331
Query: 215 IAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKE 274
V + +L ++ E ++ + +I L ++ + K ++M + TA+ +K
Sbjct: 1332 KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK--KKMEDSVGCLETAE-EVKR 1388
Query: 275 KLTTTESQLRQTRN-RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLR 333
KL L Q +VA DK L + + + + + D RQ LE + +K
Sbjct: 1389 KLQKDLEGLSQRHEEKVAAYDK-LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFD 1447
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
+ L + +++ ++RD +AE E ++ + L S + LEE A++++
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEAEARE--KETKAL-----SLARALEE-------AMEQKA 1493
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE 453
E+ + L ++ TE++D ++ +++ + ELEKSK + E ++ +L+ ++
Sbjct: 1494 ELER----LNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVE---EMKTQLEELED 1546
Query: 454 TLRVTED-----EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
L+ TED EV + + E + + + + E K++++ +++ EL K
Sbjct: 1547 ELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE--KKKQLVRQVREMEAELEDERKQ 1604
Query: 509 NEQKVI---QYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
V + E ++DL+AH + AN + LQ ++ D M+ LD + E
Sbjct: 1605 RSMAVAARKKLEMDLKDLEAHIDS-ANKNRDEAIKQLRKLQAQMKDC-MRELDDTRASRE 1662
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSR-ELAALQQDLEHRM 623
EILA Q E + K +A +I+++EEL + K + +Q R ELA + +
Sbjct: 1663 --EILA---QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQIH-RLEKIVLAL 664
+ E +++ A+ +++E + + I+ RL+K L +
Sbjct: 1718 ALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759
Score = 54.0 bits (124), Expect = 2e-06
Identities = 47/213 (22%), Positives = 92/213 (43%), Gaps = 13/213 (6%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
++ +E R ++E EL E NT+ + + L + I L S ++ N
Sbjct: 1724 KRRLEARIAQLEE--ELEEEQGNTELIND---RLKKANLQIDQINTDLNLERSHAQKNEN 1778
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL----KTGEVTTS 344
++++Q +E + + + GTVK + + LEA+ +L E L K +
Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVK---SKYKASITALEAKIAQLEEQLDNETKERQAACK 1835
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
Q+ + L+ +L+ + + Q+K + LKQ KR L+E E +R +
Sbjct: 1836 QVRRTEKKLKDVLLQVDDE-RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRR 1894
Query: 405 RTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
+ + EL+D+ + + ++ L+ DLP
Sbjct: 1895 KLQRELEDATETADAMNREVSSLKNKLRRGDLP 1927
Score = 51.2 bits (117), Expect = 1e-05
Identities = 61/303 (20%), Positives = 134/303 (44%), Gaps = 18/303 (5%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
+ ++ L + Q + L + + E+ + + K+ +I + E L
Sbjct: 1635 EAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER 1694
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
RQ + R+ + DEI S + ALEE R E R A+L +E+L +
Sbjct: 1695 AKRQAQQERDELADEIAN--SSGKGALALEEKRRL--EARIAQL--EEELEEEQGNTELI 1748
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT-SQ 345
+R+ K + Q+ + + +L + + +RQ QLE + ++L+ L+ E T S+
Sbjct: 1749 NDRLKKANLQIDQINTDL-NLERSHAQKNENARQ---QLERQNKELKVKLQEMEGTVKSK 1804
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+L+A++ + ++Q++ T + ++A +Q+ K+ K L + + + + K++
Sbjct: 1805 YKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQ 1864
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC 465
+ + +++L+ ++ E E+ + + L EL+ ET EV++
Sbjct: 1865 ADK----ASTRLKQLKRQLEEAEEEAQRANASRRK---LQRELEDATETADAMNREVSSL 1917
Query: 466 KRE 468
K +
Sbjct: 1918 KNK 1920
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 84.6 bits (200), Expect = 1e-15
Identities = 97/436 (22%), Positives = 201/436 (46%), Gaps = 37/436 (8%)
Query: 242 IRELRSESENTKA-LEEMRHELDEERTAKLAIKEKL-TTTESQLRQTRNRVAKMDKQLRE 299
++E ++ EN +A ++ EL ++ +AKL + + + T Q + ++A++ ++L +
Sbjct: 772 LKEHQAHVENLEADIKRSEGEL-QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLD 830
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
E LT V +E Q + +L+A ++++ ++ E S++ Q+ SL +V E
Sbjct: 831 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL-TQVYE 889
Query: 360 CK--------QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETEL 410
K +Q +++ V+ ++ I Q+ E K+ L ++ + I L E ET+
Sbjct: 890 SKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKF 949
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
++ +E+++ K E++++ L ++E L EL+ T L E + E
Sbjct: 950 KNQEKKMEKVKQKAKEMQETLKKKLL--DQEAKLKKELENTALELSQKEKQFNAKMLEMA 1007
Query: 471 SENKIGIQQKLAA-ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRT 529
N GI ++ E KE+I ++ REL I + E+K+ Q + ++++
Sbjct: 1008 QANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHE---- 1063
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQAR 589
I Q+ +QE+ +LK K+L EE+++ + +E +QD
Sbjct: 1064 ----------IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQE 1113
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMR---IVDE--VNKQIAAKAD--EIQE 642
+K + +N L ET+ L L+ DL ++ + E V ++ A+ D ++ E
Sbjct: 1114 QLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSE 1173
Query: 643 LFATLENKQQQIHRLE 658
L + L+ ++ L+
Sbjct: 1174 LTSKLKTTDEEFQSLK 1189
Score = 77.8 bits (183), Expect = 1e-13
Identities = 96/457 (21%), Positives = 212/457 (46%), Gaps = 33/457 (7%)
Query: 224 EVAKLRQDVETR-NVMIDEIRELRSESENTKALEEMRHELDEERTAK---LAIKEKLTTT 279
EV K R +E +V+ D+ +++ E E ++ H+ + K ++I+
Sbjct: 695 EVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKAL 754
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL---EARARKLRESL 336
+ Q+ Q + + DK L+E +A + +L +K E + +Q +L ++ E
Sbjct: 755 KDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQT 814
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
K E +QL Q+ L+ E + +Q+ ++ Q K +L+ Q + L +Q E
Sbjct: 815 KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV-QDLMQQLEKQ 873
Query: 397 KREIELKERT-----ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID-LWAELQA 450
E+E K ++ E++L+D E+ + ++E E ++EI+ L +L A
Sbjct: 874 NSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSA 933
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
++++ + +E T + K E K+ ++ A E+ +E + K+ Q +L K + E
Sbjct: 934 KEDSIHILNEEYET--KFKNQEKKMEKVKQKAKEM--QETLKKKLLDQEAKLKKEL---E 986
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI-MDLKMKLLDVVHRNEELSEI 569
++ Q ++ Q + + + Q + GIS + E +++ L VHR EL+++
Sbjct: 987 NTALELSQ--KEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHR-RELNDV 1043
Query: 570 LAKKDQELEQQDKNSRGQARV-IKIREELINVLKNK-------ETEQSRELAALQQDLEH 621
++ +++L QQ + + + ++ +E+ + LK K + E ++E+ L+++
Sbjct: 1044 ISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVK 1103
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ ++E+ +Q+ K+ + L + + +LE
Sbjct: 1104 QDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLE 1140
Score = 68.9 bits (161), Expect = 6e-11
Identities = 111/478 (23%), Positives = 215/478 (44%), Gaps = 49/478 (10%)
Query: 212 RTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKL 270
+TL + + + R+ L++ ET ++ L SE E + L+E EL++ + +
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 338
Query: 271 AIKEKLTTTE-------SQLRQTRNRV-AKMDKQLREA----EASITSLTGTVKMLEDQS 318
A K KL T QL Q + V A+ +Q+ E E I L +K + Q
Sbjct: 339 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 398
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL 378
+ Q E R E L+ T + + R L+AE+ E + IEK + + + ++QQ
Sbjct: 399 EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE 458
Query: 379 EEDLKQ-----TKRALQEQC----EITKREIELKERTETELQDSRNAIEELQAKIIELEK 429
+KQ K++ +EQ ++ ++E+ KE+ T+ +R + Q K + LEK
Sbjct: 459 LSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK-VALEK 517
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI-GIQQKLAAELLNK 488
S+ + L +E + +E+L + E E+ ESENK+ +QQ+
Sbjct: 518 SQ-SEYLKISQE-------KEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 569
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNG--ISYQDLQ 546
E+ ++ + L +N ++ + E + HN+ I E S + Q
Sbjct: 570 LELESSLE---KSLQENKNQSKDLAVHLE---AEKNKHNKEITVMVEKHKTELESLKHQQ 623
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ--QDKNSRGQARVIKIREELINVLKNK 604
+ K+++L ++ E+ ++ K +QE E +DK QA + ++ E+ + L K
Sbjct: 624 DALWTEKLQVLKQQYQT-EMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK--QQQIHRLEKI 660
+T EL +L +L ++ ++ ++++ D+ ++ LE K +Q+ H +++
Sbjct: 683 QT----ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQV 736
Score = 63.3 bits (147), Expect = 3e-09
Identities = 92/442 (20%), Positives = 197/442 (44%), Gaps = 38/442 (8%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRH--ELDEERTAKLA-IKEKLTTTESQLRQTR 287
++E+ N ++ + + + E+ + +++++H EL EE+ ++ +EK+ T E+Q+ +
Sbjct: 1540 EIESLNEVLKNYNQ-QKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMK 1598
Query: 288 NRVAKMDKQLREAEASITSLTGTVKMLED----QSRQKEVQLEARARKLRESLKTGEVTT 343
+ K+L S+ S +K LED +S K +L+ +A + ++K +
Sbjct: 1599 AELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIK--KQLL 1656
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
SQ+ ++ + + ++ + + + LEE LK + + E + + +
Sbjct: 1657 SQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVA 1716
Query: 404 ERTETELQDSRNAIEE-LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEV 462
TE E DS+ +++ + KI L+++ TE+E L Q +ET V+
Sbjct: 1717 AYTEQEEADSQGCVQKTYEEKISVLQRNL------TEKEKLLQRVGQEKEET--VSSHFE 1768
Query: 463 TTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
C+ + E I ++ A+ + +IG +Q + E K L + ++ E +
Sbjct: 1769 MRCQYQ---ERLIKLEH-AEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNN 1824
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD--VVHRNE----ELSEILAK--KD 574
+QA + + ++L +I++ K+K LD +V + E E+ E+ +K K
Sbjct: 1825 IQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKL 1884
Query: 575 QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELA---ALQQDLEHRMRIVDEVNK 631
Q L+Q D G+ + ++ EE Q + L+ A DLE ++ + +
Sbjct: 1885 QALQQMD----GRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQ 1940
Query: 632 QIAAKADEIQELFATLENKQQQ 653
++ + +Q+ L + QQ
Sbjct: 1941 KLGKEIVRLQKDLRMLRKEHQQ 1962
Score = 61.7 bits (143), Expect = 9e-09
Identities = 105/523 (20%), Positives = 237/523 (45%), Gaps = 53/523 (10%)
Query: 138 ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV 197
+LLD+ ++ ++ L+ + Q + +LE +++ N G + A+ L+T ++ +
Sbjct: 973 KLLDQEAKLKKELENTALELSQKEKQFNAKMLE-MAQANSAG--ISDAVSRLETNQKEQI 1029
Query: 198 NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEE 257
++T++ +R E +I++ E KL Q E + EI E++ + E + + E
Sbjct: 1030 ESLTEVHRR---ELNDVISIWEK------KLNQQAEE----LQEIHEIQLQ-EKEQEVAE 1075
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
++ ++ K + +++T + + + + ++ +QL++ A + SL +D+
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLA------QDE 1129
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA--- 374
++ K LE L +SLK QL++ + + AE E K+++ +LT + K+
Sbjct: 1130 TKLK-AHLEKLEVDLNKSLKENTFLQEQLVELK--MLAE--EDKRKVSELTSKLKTTDEE 1184
Query: 375 IQQLEEDLKQTKRALQEQC-EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN 433
Q L+ +++ ++L+++ E K EL + + + + +E ++I + SK N
Sbjct: 1185 FQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTN 1244
Query: 434 PDLPTEREIDLWAELQATKETLRV---TEDEVTTCKRE-KESENKIGIQQKLAAELLNKE 489
L R KE L + T E+ R+ E +N + I + A L ++
Sbjct: 1245 AIL--SRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEK 1302
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI 549
E IK++K + + ++ ++ ++ + + A+ +ES ++L + I
Sbjct: 1303 E----------NQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENI 1352
Query: 550 MDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
+ + ++ + E+S L+K+ +L Q +NS + +E I+ L+ + E+
Sbjct: 1353 NAVTLMKEELKEKKVEISS-LSKQLTDLNVQLQNSIS----LSEKEAAISSLRKQYDEEK 1407
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
EL QDL ++ + + + D+ F+ + K Q
Sbjct: 1408 CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQ 1450
Score = 59.3 bits (137), Expect = 5e-08
Identities = 106/565 (18%), Positives = 254/565 (44%), Gaps = 58/565 (10%)
Query: 139 LLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVN 198
+ +T+ IE++ + K N +D ++++ L + + G E ++E + + N
Sbjct: 1534 ITQKTIEIESLNEVLK-NYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLEN 1592
Query: 199 TVTDLSKRACHERRTLIAVG---EALVREVAKLRQDVETRNVMIDEIRELRSESENTKAL 255
V + +++ L V ++ E+ L +E+ + ++ EL+ ++E A
Sbjct: 1593 QVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAA--KLAELKRKAEQKIAA 1650
Query: 256 --EEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS---LTG 309
+++ +++E E K + L+ ++L++ V ++++L+ E+S + +
Sbjct: 1651 IKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPR 1710
Query: 310 TVKMLEDQSRQKEVQLEARARKLRE---SLKTGEVTTSQLIQQRDSLQAEV-------LE 359
+ K + + Q+E + +K E S+ +T + + QR + E +
Sbjct: 1711 SAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMR 1770
Query: 360 CKQQIEKLTVQH--------KSAIQQLEEDLKQTKR------ALQEQCEITKREIELKER 405
C+ Q + ++H +S I L+E+L++ + A + E K I+ K+
Sbjct: 1771 CQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQN 1830
Query: 406 TETELQDSRNAIEE--LQAKIIELEKSKPNPDLPTEREIDL--WAELQATKETLRVTEDE 461
E D + ++E L +I+E + + + L ++E+ EL + E L+ +
Sbjct: 1831 LENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM 1890
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQK----VI 514
K + E ++K + L+ + +++ M+ Q +L + + +QK ++
Sbjct: 1891 DGRNKPTELLEENT--EEKSKSHLV-QPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIV 1947
Query: 515 QYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEILAK 572
+ ++ +R L+ H + + ++ + + ++QE DL++K + + E + LA+
Sbjct: 1948 RLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQ 2007
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR----IVDE 628
K+QELE K + +A+ ++ EL+ + + + +++A DL+ + I+D
Sbjct: 2008 KEQELEMTIKETINKAQ--EVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDA 2065
Query: 629 VNKQIAAKADEIQELFATLENKQQQ 653
+++ AK ++Q L+ K QQ
Sbjct: 2066 REEEMTAKVRDLQTQLEELQKKYQQ 2090
Score = 56.4 bits (130), Expect = 3e-07
Identities = 105/493 (21%), Positives = 226/493 (45%), Gaps = 55/493 (11%)
Query: 185 ALRELKTQAE----DAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
AL EL+ Q + ++ N + DL + A R ++ + +L + + + + + V +
Sbjct: 536 ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHL- 594
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAI-KEKLTTTESQLRQTRNRVAKMDKQLRE 299
E + + E T +E+ + EL+ + + A+ EKL + Q + ++ + +Q +E
Sbjct: 595 EAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKE 654
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ +E+ + + +L+ + +L ESL + S++++ R L+ E+
Sbjct: 655 TLLKDKEIIFQAH-IEEMNEKTLEKLDVKQTEL-ESLSS---ELSEVLKARHKLEEELSV 709
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK-ERTETELQDSRNAIE 418
K Q +K+ Q+LE + + K Q+Q + +E E+ +RTE L+D N +E
Sbjct: 710 LKDQTDKMK-------QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 762
Query: 419 -----------ELQAKIIELE---KSKPNPDLPTEREIDLWAELQ-ATKETLRVTEDEVT 463
E QA + LE K ++D++ Q AT E + E+++
Sbjct: 763 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 822
Query: 464 TCKR---EKESENKIGIQQKLAAELLNKEEIIGKM---QIQTRELIKNIKLNEQKVIQYE 517
++ + E+E +I + +++A K+++ ++ +IQ ++L++ + E++ + E
Sbjct: 823 QLQQKLLDLETE-RILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQL---EKQNSEME 878
Query: 518 QYVRDL-QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKD-- 574
Q V+ L Q + + + + +++E M L+M+ ++ AK+D
Sbjct: 879 QKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 938
Query: 575 ----QELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEV 629
+E E + KN + +K + +E+ LK K +Q A L+++LE+ + +
Sbjct: 939 HILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQE---AKLKKELENTALELSQK 995
Query: 630 NKQIAAKADEIQE 642
KQ AK E+ +
Sbjct: 996 EKQFNAKMLEMAQ 1008
Score = 52.0 bits (119), Expect = 7e-06
Identities = 84/387 (21%), Positives = 171/387 (44%), Gaps = 34/387 (8%)
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
+KM+K+ E + S T + LED QK +++E+ L+ + ++ +L+Q+
Sbjct: 1507 SKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKL 1566
Query: 351 DSLQAEVLECK----QQIEKLTVQHKSAIQQLEEDLKQTKRALQE-QCEITKREIELK-- 403
Q E+ E K ++ E+ + ++ + ++ +L+ K+ L+ + +E ELK
Sbjct: 1567 QHFQ-ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1625
Query: 404 -ERTETE----LQDSRNAIEELQAKI-----IELEKSKPNPDLPTEREI-DLWAELQATK 452
+R E+E L + + E+ A I ++E+ + TE + +L +LQ +
Sbjct: 1626 EDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERE 1685
Query: 453 ETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEI--IGKMQIQTRELIKNIKLN- 509
+ + E+++ + + + + K A +EE G +Q E I ++ N
Sbjct: 1686 REVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNL 1745
Query: 510 --EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNEEL 566
++K++Q ++ + CQ I + + ++ D M + H EEL
Sbjct: 1746 TEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSM----IGHLQEEL 1801
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN-KETEQSRELAALQQDLEHRMRI 625
E KK + Q G I+ ++ L NV + ++T Q +EL Q LE +++
Sbjct: 1802 EE-KNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTC--QILEQKIKE 1858
Query: 626 VDE-VNKQIAAKADEIQELFATLENKQ 651
+D + +Q E++EL + E Q
Sbjct: 1859 LDSCLVRQKEVHRVEMEELTSKYEKLQ 1885
Score = 50.4 bits (115), Expect = 2e-05
Identities = 101/488 (20%), Positives = 216/488 (44%), Gaps = 46/488 (9%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
+E+ E+ V T L++ + + A +L ++ KL+ +E + +D + L+
Sbjct: 1092 KEITWLKEEGVKQDTTLNELQ-EQLKQKSAHVNSLAQDETKLKAHLE--KLEVDLNKSLK 1148
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
+ + L E++ +E++ + KL TT+ + + ++ K +K L +
Sbjct: 1149 ENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1208
Query: 307 LTGTVKM-LEDQSRQKEVQLEARARKLRE--SLKTGEVTTS-QLIQQRDSLQAEVL---- 358
L+ + + L+ ++ E LEA+ +L S KT + + Q R + E L
Sbjct: 1209 LSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKT 1268
Query: 359 ----ECKQQIEKLTVQHKS---AIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
E + Q+ +LT + + + QQ L++ + ++ + + KE + E
Sbjct: 1269 CTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGG 1328
Query: 412 DSRNAIEELQAKIIELEKS-KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
+ + A E ++ I +L+K N + T + EL+ K + ++T +
Sbjct: 1329 NQQQAASEKESCITQLKKELSENINAVTLMK----EELKEKKVEISSLSKQLTDLN--VQ 1382
Query: 471 SENKIGIQQKLAA-ELLNKEEIIGKMQI--QTREL-IKNIKLNEQKVIQYEQYVRDLQAH 526
+N I + +K AA L K+ K ++ Q ++L K L+++K+ EQ D ++
Sbjct: 1383 LQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQV--DDWSN 1440
Query: 527 NRTIANCQESPNGISYQDLQQEI-MDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
+ + +Q+ +E+ + L++K + ++E+++ L K +EL+QQ+K
Sbjct: 1441 KFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQIN--LLK--EELDQQNK--- 1493
Query: 586 GQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
R ++ E+ + E ++S L+ +L+ + + E+ I K EI+ L
Sbjct: 1494 ---RFDCLKGEMEDDKSKMEKKESN----LETELKSQTARIMELEDHITQKTIEIESLNE 1546
Query: 646 TLENKQQQ 653
L+N QQ
Sbjct: 1547 VLKNYNQQ 1554
Score = 44.0 bits (99), Expect = 0.002
Identities = 55/293 (18%), Positives = 125/293 (42%), Gaps = 23/293 (7%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
A + L+ +D T+ + + + + LVR+ R ++E ++++
Sbjct: 1827 AKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQA 1886
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
L+ K E + +E+ + L + L+ E+Q ++A +++ ++ I
Sbjct: 1887 LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEI 1946
Query: 305 TSLTGTVKMLE--------------DQSRQKEVQLEARARKLRESLKTGEVT---TSQLI 347
L ++ML DQ R+++++ E +L+ + ++ +QL
Sbjct: 1947 VRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLA 2006
Query: 348 QQRDSLQAEVLEC---KQQIE-KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
Q+ L+ + E Q++E +L H+ QL + + + L+ + + ++ +
Sbjct: 2007 QKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAR 2066
Query: 404 ERTET-ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
E T +++D + +EELQ K + + + NP ++L +L A K TL
Sbjct: 2067 EEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQL-AQKTTL 2118
Score = 41.9 bits (94), Expect = 0.007
Identities = 52/258 (20%), Positives = 117/258 (45%), Gaps = 34/258 (13%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
+++ND F+L GA RE + ++ V DL ++ L E+ K D
Sbjct: 1923 AQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQEL---------EILKKEYDQ 1973
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
E + E +L E ++ L+++ E + +LA KE+ E +++T N+ +
Sbjct: 1974 EREEKIKQEQEDL--ELKHNSTLKQLMREFN----TQLAQKEQ--ELEMTIKETINKAQE 2025
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
++ +L E+ T+ L + +K+ L+ A++ E L E +
Sbjct: 2026 VEAELLESHQEETN------QLLKKIAEKDDDLKRTAKRYEEILDARE----------EE 2069
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
+ A+V + + Q+E+L +++ ++Q E ++ Q ++ ++ + + ++ + Q+
Sbjct: 2070 MTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISD-SKLKEQE 2128
Query: 413 SRNAIEELQAKIIELEKS 430
R I L+ ++ + EK+
Sbjct: 2129 FREQIHNLEDRLKKYEKN 2146
Score = 34.3 bits (75), Expect = 1.5
Identities = 78/376 (20%), Positives = 154/376 (40%), Gaps = 28/376 (7%)
Query: 200 VTDLSKRACHERRTLIAVGEALVREVA---KLRQDVETRNVMIDEIRELRSESENTKA-L 255
++ L + + + L VG+ V+ ++R + R + ++ + E ++ L
Sbjct: 1738 ISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHL 1797
Query: 256 EEMRHELDEERTAKLA--IKEKLTTTESQLRQTRNRVAK-MDKQLREAEASITSLTGTVK 312
+E E +++ + +A ++++ Q +Q V + K L+E E + L +K
Sbjct: 1798 QEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIK 1857
Query: 313 MLED-QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
L+ RQKEV R E L T + Q +QQ D ++ E+ + H
Sbjct: 1858 ELDSCLVRQKEVH-----RVEMEEL-TSKYEKLQALQQMDGRNKPTELLEENTEEKSKSH 1911
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ-DSRNAIEELQAKIIELEKS 430
+L +++ L+ + +RE + + LQ D R +E Q ELE
Sbjct: 1912 LVQ-PKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEIL 1967
Query: 431 KPNPDLPTEREIDLWAELQATKE--TLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
K D E +I E K TL+ E T +KE E ++ I++ + +
Sbjct: 1968 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVE 2027
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE 548
E++ Q +T +L+K K+ + + ++ I + +E +DLQ +
Sbjct: 2028 AELLESHQEETNQLLK-------KIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQ 2080
Query: 549 IMDLKMKLLDVVHRNE 564
+ +L+ K + + E
Sbjct: 2081 LEELQKKYQQKLEQEE 2096
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 84.6 bits (200), Expect = 1e-15
Identities = 97/436 (22%), Positives = 201/436 (46%), Gaps = 37/436 (8%)
Query: 242 IRELRSESENTKA-LEEMRHELDEERTAKLAIKEKL-TTTESQLRQTRNRVAKMDKQLRE 299
++E ++ EN +A ++ EL ++ +AKL + + + T Q + ++A++ ++L +
Sbjct: 772 LKEHQAHVENLEADIKRSEGEL-QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLD 830
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
E LT V +E Q + +L+A ++++ ++ E S++ Q+ SL +V E
Sbjct: 831 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL-TQVYE 889
Query: 360 CK--------QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETEL 410
K +Q +++ V+ ++ I Q+ E K+ L ++ + I L E ET+
Sbjct: 890 SKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKF 949
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
++ +E+++ K E++++ L ++E L EL+ T L E + E
Sbjct: 950 KNQEKKMEKVKQKAKEMQETLKKKLL--DQEAKLKKELENTALELSQKEKQFNAKMLEMA 1007
Query: 471 SENKIGIQQKLAA-ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRT 529
N GI ++ E KE+I ++ REL I + E+K+ Q + ++++
Sbjct: 1008 QANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHE---- 1063
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQAR 589
I Q+ +QE+ +LK K+L EE+++ + +E +QD
Sbjct: 1064 ----------IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQE 1113
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMR---IVDE--VNKQIAAKAD--EIQE 642
+K + +N L ET+ L L+ DL ++ + E V ++ A+ D ++ E
Sbjct: 1114 QLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSE 1173
Query: 643 LFATLENKQQQIHRLE 658
L + L+ ++ L+
Sbjct: 1174 LTSKLKTTDEEFQSLK 1189
Score = 77.8 bits (183), Expect = 1e-13
Identities = 96/457 (21%), Positives = 212/457 (46%), Gaps = 33/457 (7%)
Query: 224 EVAKLRQDVETR-NVMIDEIRELRSESENTKALEEMRHELDEERTAK---LAIKEKLTTT 279
EV K R +E +V+ D+ +++ E E ++ H+ + K ++I+
Sbjct: 695 EVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKAL 754
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL---EARARKLRESL 336
+ Q+ Q + + DK L+E +A + +L +K E + +Q +L ++ E
Sbjct: 755 KDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQT 814
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
K E +QL Q+ L+ E + +Q+ ++ Q K +L+ Q + L +Q E
Sbjct: 815 KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV-QDLMQQLEKQ 873
Query: 397 KREIELKERT-----ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID-LWAELQA 450
E+E K ++ E++L+D E+ + ++E E ++EI+ L +L A
Sbjct: 874 NSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSA 933
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
++++ + +E T + K E K+ ++ A E+ +E + K+ Q +L K + E
Sbjct: 934 KEDSIHILNEEYET--KFKNQEKKMEKVKQKAKEM--QETLKKKLLDQEAKLKKEL---E 986
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI-MDLKMKLLDVVHRNEELSEI 569
++ Q ++ Q + + + Q + GIS + E +++ L VHR EL+++
Sbjct: 987 NTALELSQ--KEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHR-RELNDV 1043
Query: 570 LAKKDQELEQQDKNSRGQARV-IKIREELINVLKNK-------ETEQSRELAALQQDLEH 621
++ +++L QQ + + + ++ +E+ + LK K + E ++E+ L+++
Sbjct: 1044 ISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVK 1103
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ ++E+ +Q+ K+ + L + + +LE
Sbjct: 1104 QDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLE 1140
Score = 68.9 bits (161), Expect = 6e-11
Identities = 111/478 (23%), Positives = 215/478 (44%), Gaps = 49/478 (10%)
Query: 212 RTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKL 270
+TL + + + R+ L++ ET ++ L SE E + L+E EL++ + +
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 338
Query: 271 AIKEKLTTTE-------SQLRQTRNRV-AKMDKQLREA----EASITSLTGTVKMLEDQS 318
A K KL T QL Q + V A+ +Q+ E E I L +K + Q
Sbjct: 339 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 398
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL 378
+ Q E R E L+ T + + R L+AE+ E + IEK + + + ++QQ
Sbjct: 399 EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE 458
Query: 379 EEDLKQ-----TKRALQEQC----EITKREIELKERTETELQDSRNAIEELQAKIIELEK 429
+KQ K++ +EQ ++ ++E+ KE+ T+ +R + Q K + LEK
Sbjct: 459 LSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK-VALEK 517
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI-GIQQKLAAELLNK 488
S+ + L +E + +E+L + E E+ ESENK+ +QQ+
Sbjct: 518 SQ-SEYLKISQE-------KEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 569
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNG--ISYQDLQ 546
E+ ++ + L +N ++ + E + HN+ I E S + Q
Sbjct: 570 LELESSLE---KSLQENKNQSKDLAVHLE---AEKNKHNKEITVMVEKHKTELESLKHQQ 623
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ--QDKNSRGQARVIKIREELINVLKNK 604
+ K+++L ++ E+ ++ K +QE E +DK QA + ++ E+ + L K
Sbjct: 624 DALWTEKLQVLKQQYQT-EMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK--QQQIHRLEKI 660
+T EL +L +L ++ ++ ++++ D+ ++ LE K +Q+ H +++
Sbjct: 683 QT----ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQV 736
Score = 63.3 bits (147), Expect = 3e-09
Identities = 92/442 (20%), Positives = 197/442 (44%), Gaps = 38/442 (8%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRH--ELDEERTAKLA-IKEKLTTTESQLRQTR 287
++E+ N ++ + + + E+ + +++++H EL EE+ ++ +EK+ T E+Q+ +
Sbjct: 1540 EIESLNEVLKNYNQ-QKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMK 1598
Query: 288 NRVAKMDKQLREAEASITSLTGTVKMLED----QSRQKEVQLEARARKLRESLKTGEVTT 343
+ K+L S+ S +K LED +S K +L+ +A + ++K +
Sbjct: 1599 AELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIK--KQLL 1656
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
SQ+ ++ + + ++ + + + LEE LK + + E + + +
Sbjct: 1657 SQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVA 1716
Query: 404 ERTETELQDSRNAIEE-LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEV 462
TE E DS+ +++ + KI L+++ TE+E L Q +ET V+
Sbjct: 1717 AYTEQEEADSQGCVQKTYEEKISVLQRNL------TEKEKLLQRVGQEKEET--VSSHFE 1768
Query: 463 TTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
C+ + E I ++ A+ + +IG +Q + E K L + ++ E +
Sbjct: 1769 MRCQYQ---ERLIKLEH-AEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNN 1824
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD--VVHRNE----ELSEILAK--KD 574
+QA + + ++L +I++ K+K LD +V + E E+ E+ +K K
Sbjct: 1825 IQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKL 1884
Query: 575 QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELA---ALQQDLEHRMRIVDEVNK 631
Q L+Q D G+ + ++ EE Q + L+ A DLE ++ + +
Sbjct: 1885 QALQQMD----GRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQ 1940
Query: 632 QIAAKADEIQELFATLENKQQQ 653
++ + +Q+ L + QQ
Sbjct: 1941 KLGKEIVRLQKDLRMLRKEHQQ 1962
Score = 61.7 bits (143), Expect = 9e-09
Identities = 105/523 (20%), Positives = 237/523 (45%), Gaps = 53/523 (10%)
Query: 138 ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV 197
+LLD+ ++ ++ L+ + Q + +LE +++ N G + A+ L+T ++ +
Sbjct: 973 KLLDQEAKLKKELENTALELSQKEKQFNAKMLE-MAQANSAG--ISDAVSRLETNQKEQI 1029
Query: 198 NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEE 257
++T++ +R E +I++ E KL Q E + EI E++ + E + + E
Sbjct: 1030 ESLTEVHRR---ELNDVISIWEK------KLNQQAEE----LQEIHEIQLQ-EKEQEVAE 1075
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
++ ++ K + +++T + + + + ++ +QL++ A + SL +D+
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLA------QDE 1129
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA--- 374
++ K LE L +SLK QL++ + + AE E K+++ +LT + K+
Sbjct: 1130 TKLK-AHLEKLEVDLNKSLKENTFLQEQLVELK--MLAE--EDKRKVSELTSKLKTTDEE 1184
Query: 375 IQQLEEDLKQTKRALQEQC-EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN 433
Q L+ +++ ++L+++ E K EL + + + + +E ++I + SK N
Sbjct: 1185 FQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTN 1244
Query: 434 PDLPTEREIDLWAELQATKETLRV---TEDEVTTCKRE-KESENKIGIQQKLAAELLNKE 489
L R KE L + T E+ R+ E +N + I + A L ++
Sbjct: 1245 AIL--SRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEK 1302
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI 549
E IK++K + + ++ ++ ++ + + A+ +ES ++L + I
Sbjct: 1303 E----------NQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENI 1352
Query: 550 MDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
+ + ++ + E+S L+K+ +L Q +NS + +E I+ L+ + E+
Sbjct: 1353 NAVTLMKEELKEKKVEISS-LSKQLTDLNVQLQNSIS----LSEKEAAISSLRKQYDEEK 1407
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
EL QDL ++ + + + D+ F+ + K Q
Sbjct: 1408 CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQ 1450
Score = 59.3 bits (137), Expect = 5e-08
Identities = 106/565 (18%), Positives = 254/565 (44%), Gaps = 58/565 (10%)
Query: 139 LLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVN 198
+ +T+ IE++ + K N +D ++++ L + + G E ++E + + N
Sbjct: 1534 ITQKTIEIESLNEVLK-NYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLEN 1592
Query: 199 TVTDLSKRACHERRTLIAVG---EALVREVAKLRQDVETRNVMIDEIRELRSESENTKAL 255
V + +++ L V ++ E+ L +E+ + ++ EL+ ++E A
Sbjct: 1593 QVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAA--KLAELKRKAEQKIAA 1650
Query: 256 --EEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS---LTG 309
+++ +++E E K + L+ ++L++ V ++++L+ E+S + +
Sbjct: 1651 IKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPR 1710
Query: 310 TVKMLEDQSRQKEVQLEARARKLRE---SLKTGEVTTSQLIQQRDSLQAEV-------LE 359
+ K + + Q+E + +K E S+ +T + + QR + E +
Sbjct: 1711 SAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMR 1770
Query: 360 CKQQIEKLTVQH--------KSAIQQLEEDLKQTKR------ALQEQCEITKREIELKER 405
C+ Q + ++H +S I L+E+L++ + A + E K I+ K+
Sbjct: 1771 CQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQN 1830
Query: 406 TETELQDSRNAIEE--LQAKIIELEKSKPNPDLPTEREIDL--WAELQATKETLRVTEDE 461
E D + ++E L +I+E + + + L ++E+ EL + E L+ +
Sbjct: 1831 LENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM 1890
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQK----VI 514
K + E ++K + L+ + +++ M+ Q +L + + +QK ++
Sbjct: 1891 DGRNKPTELLEENT--EEKSKSHLV-QPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIV 1947
Query: 515 QYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEILAK 572
+ ++ +R L+ H + + ++ + + ++QE DL++K + + E + LA+
Sbjct: 1948 RLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQ 2007
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR----IVDE 628
K+QELE K + +A+ ++ EL+ + + + +++A DL+ + I+D
Sbjct: 2008 KEQELEMTIKETINKAQ--EVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDA 2065
Query: 629 VNKQIAAKADEIQELFATLENKQQQ 653
+++ AK ++Q L+ K QQ
Sbjct: 2066 REEEMTAKVRDLQTQLEELQKKYQQ 2090
Score = 56.4 bits (130), Expect = 3e-07
Identities = 105/493 (21%), Positives = 226/493 (45%), Gaps = 55/493 (11%)
Query: 185 ALRELKTQAE----DAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
AL EL+ Q + ++ N + DL + A R ++ + +L + + + + + V +
Sbjct: 536 ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHL- 594
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAI-KEKLTTTESQLRQTRNRVAKMDKQLRE 299
E + + E T +E+ + EL+ + + A+ EKL + Q + ++ + +Q +E
Sbjct: 595 EAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKE 654
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ +E+ + + +L+ + +L ESL + S++++ R L+ E+
Sbjct: 655 TLLKDKEIIFQAH-IEEMNEKTLEKLDVKQTEL-ESLSS---ELSEVLKARHKLEEELSV 709
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK-ERTETELQDSRNAIE 418
K Q +K+ Q+LE + + K Q+Q + +E E+ +RTE L+D N +E
Sbjct: 710 LKDQTDKMK-------QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 762
Query: 419 -----------ELQAKIIELE---KSKPNPDLPTEREIDLWAELQ-ATKETLRVTEDEVT 463
E QA + LE K ++D++ Q AT E + E+++
Sbjct: 763 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 822
Query: 464 TCKR---EKESENKIGIQQKLAAELLNKEEIIGKM---QIQTRELIKNIKLNEQKVIQYE 517
++ + E+E +I + +++A K+++ ++ +IQ ++L++ + E++ + E
Sbjct: 823 QLQQKLLDLETE-RILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQL---EKQNSEME 878
Query: 518 QYVRDL-QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKD-- 574
Q V+ L Q + + + + +++E M L+M+ ++ AK+D
Sbjct: 879 QKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 938
Query: 575 ----QELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEV 629
+E E + KN + +K + +E+ LK K +Q A L+++LE+ + +
Sbjct: 939 HILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQE---AKLKKELENTALELSQK 995
Query: 630 NKQIAAKADEIQE 642
KQ AK E+ +
Sbjct: 996 EKQFNAKMLEMAQ 1008
Score = 52.0 bits (119), Expect = 7e-06
Identities = 84/387 (21%), Positives = 171/387 (44%), Gaps = 34/387 (8%)
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
+KM+K+ E + S T + LED QK +++E+ L+ + ++ +L+Q+
Sbjct: 1507 SKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKL 1566
Query: 351 DSLQAEVLECK----QQIEKLTVQHKSAIQQLEEDLKQTKRALQE-QCEITKREIELK-- 403
Q E+ E K ++ E+ + ++ + ++ +L+ K+ L+ + +E ELK
Sbjct: 1567 QHFQ-ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1625
Query: 404 -ERTETE----LQDSRNAIEELQAKI-----IELEKSKPNPDLPTEREI-DLWAELQATK 452
+R E+E L + + E+ A I ++E+ + TE + +L +LQ +
Sbjct: 1626 EDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERE 1685
Query: 453 ETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEI--IGKMQIQTRELIKNIKLN- 509
+ + E+++ + + + + K A +EE G +Q E I ++ N
Sbjct: 1686 REVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNL 1745
Query: 510 --EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNEEL 566
++K++Q ++ + CQ I + + ++ D M + H EEL
Sbjct: 1746 TEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSM----IGHLQEEL 1801
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN-KETEQSRELAALQQDLEHRMRI 625
E KK + Q G I+ ++ L NV + ++T Q +EL Q LE +++
Sbjct: 1802 EE-KNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTC--QILEQKIKE 1858
Query: 626 VDE-VNKQIAAKADEIQELFATLENKQ 651
+D + +Q E++EL + E Q
Sbjct: 1859 LDSCLVRQKEVHRVEMEELTSKYEKLQ 1885
Score = 50.4 bits (115), Expect = 2e-05
Identities = 101/488 (20%), Positives = 216/488 (44%), Gaps = 46/488 (9%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
+E+ E+ V T L++ + + A +L ++ KL+ +E + +D + L+
Sbjct: 1092 KEITWLKEEGVKQDTTLNELQ-EQLKQKSAHVNSLAQDETKLKAHLE--KLEVDLNKSLK 1148
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
+ + L E++ +E++ + KL TT+ + + ++ K +K L +
Sbjct: 1149 ENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1208
Query: 307 LTGTVKM-LEDQSRQKEVQLEARARKLRE--SLKTGEVTTS-QLIQQRDSLQAEVL---- 358
L+ + + L+ ++ E LEA+ +L S KT + + Q R + E L
Sbjct: 1209 LSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKT 1268
Query: 359 ----ECKQQIEKLTVQHKS---AIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
E + Q+ +LT + + + QQ L++ + ++ + + KE + E
Sbjct: 1269 CTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGG 1328
Query: 412 DSRNAIEELQAKIIELEKS-KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
+ + A E ++ I +L+K N + T + EL+ K + ++T +
Sbjct: 1329 NQQQAASEKESCITQLKKELSENINAVTLMK----EELKEKKVEISSLSKQLTDLN--VQ 1382
Query: 471 SENKIGIQQKLAA-ELLNKEEIIGKMQI--QTREL-IKNIKLNEQKVIQYEQYVRDLQAH 526
+N I + +K AA L K+ K ++ Q ++L K L+++K+ EQ D ++
Sbjct: 1383 LQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQV--DDWSN 1440
Query: 527 NRTIANCQESPNGISYQDLQQEI-MDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
+ + +Q+ +E+ + L++K + ++E+++ L K +EL+QQ+K
Sbjct: 1441 KFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQIN--LLK--EELDQQNK--- 1493
Query: 586 GQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
R ++ E+ + E ++S L+ +L+ + + E+ I K EI+ L
Sbjct: 1494 ---RFDCLKGEMEDDKSKMEKKESN----LETELKSQTARIMELEDHITQKTIEIESLNE 1546
Query: 646 TLENKQQQ 653
L+N QQ
Sbjct: 1547 VLKNYNQQ 1554
Score = 44.0 bits (99), Expect = 0.002
Identities = 55/293 (18%), Positives = 125/293 (42%), Gaps = 23/293 (7%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
A + L+ +D T+ + + + + LVR+ R ++E ++++
Sbjct: 1827 AKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQA 1886
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
L+ K E + +E+ + L + L+ E+Q ++A +++ ++ I
Sbjct: 1887 LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEI 1946
Query: 305 TSLTGTVKMLE--------------DQSRQKEVQLEARARKLRESLKTGEVT---TSQLI 347
L ++ML DQ R+++++ E +L+ + ++ +QL
Sbjct: 1947 VRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLA 2006
Query: 348 QQRDSLQAEVLEC---KQQIE-KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
Q+ L+ + E Q++E +L H+ QL + + + L+ + + ++ +
Sbjct: 2007 QKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAR 2066
Query: 404 ERTET-ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
E T +++D + +EELQ K + + + NP ++L +L A K TL
Sbjct: 2067 EEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQL-AQKTTL 2118
Score = 41.9 bits (94), Expect = 0.007
Identities = 52/258 (20%), Positives = 117/258 (45%), Gaps = 34/258 (13%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
+++ND F+L GA RE + ++ V DL ++ L E+ K D
Sbjct: 1923 AQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQEL---------EILKKEYDQ 1973
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
E + E +L E ++ L+++ E + +LA KE+ E +++T N+ +
Sbjct: 1974 EREEKIKQEQEDL--ELKHNSTLKQLMREFN----TQLAQKEQ--ELEMTIKETINKAQE 2025
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
++ +L E+ T+ L + +K+ L+ A++ E L E +
Sbjct: 2026 VEAELLESHQEETN------QLLKKIAEKDDDLKRTAKRYEEILDARE----------EE 2069
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
+ A+V + + Q+E+L +++ ++Q E ++ Q ++ ++ + + ++ + Q+
Sbjct: 2070 MTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISD-SKLKEQE 2128
Query: 413 SRNAIEELQAKIIELEKS 430
R I L+ ++ + EK+
Sbjct: 2129 FREQIHNLEDRLKKYEKN 2146
Score = 34.3 bits (75), Expect = 1.5
Identities = 78/376 (20%), Positives = 154/376 (40%), Gaps = 28/376 (7%)
Query: 200 VTDLSKRACHERRTLIAVGEALVREVA---KLRQDVETRNVMIDEIRELRSESENTKA-L 255
++ L + + + L VG+ V+ ++R + R + ++ + E ++ L
Sbjct: 1738 ISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHL 1797
Query: 256 EEMRHELDEERTAKLA--IKEKLTTTESQLRQTRNRVAK-MDKQLREAEASITSLTGTVK 312
+E E +++ + +A ++++ Q +Q V + K L+E E + L +K
Sbjct: 1798 QEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIK 1857
Query: 313 MLED-QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
L+ RQKEV R E L T + Q +QQ D ++ E+ + H
Sbjct: 1858 ELDSCLVRQKEVH-----RVEMEEL-TSKYEKLQALQQMDGRNKPTELLEENTEEKSKSH 1911
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ-DSRNAIEELQAKIIELEKS 430
+L +++ L+ + +RE + + LQ D R +E Q ELE
Sbjct: 1912 LVQ-PKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEIL 1967
Query: 431 KPNPDLPTEREIDLWAELQATKE--TLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
K D E +I E K TL+ E T +KE E ++ I++ + +
Sbjct: 1968 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVE 2027
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE 548
E++ Q +T +L+K K+ + + ++ I + +E +DLQ +
Sbjct: 2028 AELLESHQEETNQLLK-------KIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQ 2080
Query: 549 IMDLKMKLLDVVHRNE 564
+ +L+ K + + E
Sbjct: 2081 LEELQKKYQQKLEQEE 2096
>AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golgin
subfamily a, 4 variant protein.
Length = 1310
Score = 84.6 bits (200), Expect = 1e-15
Identities = 97/436 (22%), Positives = 201/436 (46%), Gaps = 37/436 (8%)
Query: 242 IRELRSESENTKA-LEEMRHELDEERTAKLAIKEKL-TTTESQLRQTRNRVAKMDKQLRE 299
++E ++ EN +A ++ EL ++ +AKL + + + T Q + ++A++ ++L +
Sbjct: 803 LKEHQAHVENLEADIKRSEGEL-QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLD 861
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
E LT V +E Q + +L+A ++++ ++ E S++ Q+ SL +V E
Sbjct: 862 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL-TQVYE 920
Query: 360 CK--------QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETEL 410
K +Q +++ V+ ++ I Q+ E K+ L ++ + I L E ET+
Sbjct: 921 SKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKF 980
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
++ +E+++ K E++++ L ++E L EL+ T L E + E
Sbjct: 981 KNQEKKMEKVKQKAKEMQETLKKKLL--DQEAKLKKELENTALELSQKEKQFNAKMLEMA 1038
Query: 471 SENKIGIQQKLAA-ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRT 529
N GI ++ E KE+I ++ REL I + E+K+ Q + ++++
Sbjct: 1039 QANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHE---- 1094
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQAR 589
I Q+ +QE+ +LK K+L EE+++ + +E +QD
Sbjct: 1095 ----------IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQE 1144
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMR---IVDE--VNKQIAAKAD--EIQE 642
+K + +N L ET+ L L+ DL ++ + E V ++ A+ D ++ E
Sbjct: 1145 QLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSE 1204
Query: 643 LFATLENKQQQIHRLE 658
L + L+ ++ L+
Sbjct: 1205 LTSKLKTTDEEFQSLK 1220
Score = 77.8 bits (183), Expect = 1e-13
Identities = 96/457 (21%), Positives = 212/457 (46%), Gaps = 33/457 (7%)
Query: 224 EVAKLRQDVETR-NVMIDEIRELRSESENTKALEEMRHELDEERTAK---LAIKEKLTTT 279
EV K R +E +V+ D+ +++ E E ++ H+ + K ++I+
Sbjct: 726 EVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKAL 785
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL---EARARKLRESL 336
+ Q+ Q + + DK L+E +A + +L +K E + +Q +L ++ E
Sbjct: 786 KDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQT 845
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
K E +QL Q+ L+ E + +Q+ ++ Q K +L+ Q + L +Q E
Sbjct: 846 KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV-QDLMQQLEKQ 904
Query: 397 KREIELKERT-----ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID-LWAELQA 450
E+E K ++ E++L+D E+ + ++E E ++EI+ L +L A
Sbjct: 905 NSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSA 964
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
++++ + +E T + K E K+ ++ A E+ +E + K+ Q +L K + E
Sbjct: 965 KEDSIHILNEEYET--KFKNQEKKMEKVKQKAKEM--QETLKKKLLDQEAKLKKEL---E 1017
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI-MDLKMKLLDVVHRNEELSEI 569
++ Q ++ Q + + + Q + GIS + E +++ L VHR EL+++
Sbjct: 1018 NTALELSQ--KEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHR-RELNDV 1074
Query: 570 LAKKDQELEQQDKNSRGQARV-IKIREELINVLKNK-------ETEQSRELAALQQDLEH 621
++ +++L QQ + + + ++ +E+ + LK K + E ++E+ L+++
Sbjct: 1075 ISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVK 1134
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ ++E+ +Q+ K+ + L + + +LE
Sbjct: 1135 QDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLE 1171
Score = 68.9 bits (161), Expect = 6e-11
Identities = 111/478 (23%), Positives = 215/478 (44%), Gaps = 49/478 (10%)
Query: 212 RTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKL 270
+TL + + + R+ L++ ET ++ L SE E + L+E EL++ + +
Sbjct: 310 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 369
Query: 271 AIKEKLTTTE-------SQLRQTRNRV-AKMDKQLREA----EASITSLTGTVKMLEDQS 318
A K KL T QL Q + V A+ +Q+ E E I L +K + Q
Sbjct: 370 AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQG 429
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL 378
+ Q E R E L+ T + + R L+AE+ E + IEK + + + ++QQ
Sbjct: 430 EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE 489
Query: 379 EEDLKQ-----TKRALQEQC----EITKREIELKERTETELQDSRNAIEELQAKIIELEK 429
+KQ K++ +EQ ++ ++E+ KE+ T+ +R + Q K + LEK
Sbjct: 490 LSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK-VALEK 548
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI-GIQQKLAAELLNK 488
S+ + L +E + +E+L + E E+ ESENK+ +QQ+
Sbjct: 549 SQ-SEYLKISQE-------KEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 600
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNG--ISYQDLQ 546
E+ ++ + L +N ++ + E + HN+ I E S + Q
Sbjct: 601 LELESSLE---KSLQENKNQSKDLAVHLE---AEKNKHNKEITVMVEKHKTELESLKHQQ 654
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ--QDKNSRGQARVIKIREELINVLKNK 604
+ K+++L ++ E+ ++ K +QE E +DK QA + ++ E+ + L K
Sbjct: 655 DALWTEKLQVLKQQYQT-EMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 713
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK--QQQIHRLEKI 660
+T EL +L +L ++ ++ ++++ D+ ++ LE K +Q+ H +++
Sbjct: 714 QT----ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQV 767
Score = 56.4 bits (130), Expect = 3e-07
Identities = 105/493 (21%), Positives = 226/493 (45%), Gaps = 55/493 (11%)
Query: 185 ALRELKTQAE----DAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
AL EL+ Q + ++ N + DL + A R ++ + +L + + + + + V +
Sbjct: 567 ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHL- 625
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAI-KEKLTTTESQLRQTRNRVAKMDKQLRE 299
E + + E T +E+ + EL+ + + A+ EKL + Q + ++ + +Q +E
Sbjct: 626 EAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKE 685
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ +E+ + + +L+ + +L ESL + S++++ R L+ E+
Sbjct: 686 TLLKDKEIIFQAH-IEEMNEKTLEKLDVKQTEL-ESLSS---ELSEVLKARHKLEEELSV 740
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK-ERTETELQDSRNAIE 418
K Q +K+ Q+LE + + K Q+Q + +E E+ +RTE L+D N +E
Sbjct: 741 LKDQTDKMK-------QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 793
Query: 419 -----------ELQAKIIELE---KSKPNPDLPTEREIDLWAELQ-ATKETLRVTEDEVT 463
E QA + LE K ++D++ Q AT E + E+++
Sbjct: 794 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 853
Query: 464 TCKR---EKESENKIGIQQKLAAELLNKEEIIGKM---QIQTRELIKNIKLNEQKVIQYE 517
++ + E+E +I + +++A K+++ ++ +IQ ++L++ + E++ + E
Sbjct: 854 QLQQKLLDLETE-RILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQL---EKQNSEME 909
Query: 518 QYVRDL-QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKD-- 574
Q V+ L Q + + + + +++E M L+M+ ++ AK+D
Sbjct: 910 QKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 969
Query: 575 ----QELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEV 629
+E E + KN + +K + +E+ LK K +Q A L+++LE+ + +
Sbjct: 970 HILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQE---AKLKKELENTALELSQK 1026
Query: 630 NKQIAAKADEIQE 642
KQ AK E+ +
Sbjct: 1027 EKQFNAKMLEMAQ 1039
Score = 48.8 bits (111), Expect = 6e-05
Identities = 62/300 (20%), Positives = 145/300 (48%), Gaps = 32/300 (10%)
Query: 138 ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV 197
+LLD+ ++ ++ L+ + Q + +LE +++ N G + A+ L+T ++ +
Sbjct: 1004 KLLDQEAKLKKELENTALELSQKEKQFNAKMLE-MAQANSAG--ISDAVSRLETNQKEQI 1060
Query: 198 NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEE 257
++T++ +R E +I++ E KL Q E + EI E++ + E + + E
Sbjct: 1061 ESLTEVHRR---ELNDVISIWEK------KLNQQAEE----LQEIHEIQLQ-EKEQEVAE 1106
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
++ ++ K + +++T + + + + ++ +QL++ A + SL +D+
Sbjct: 1107 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLA------QDE 1160
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA--- 374
++ K LE L +SLK QL++ + + AE E K+++ +LT + K+
Sbjct: 1161 TKLK-AHLEKLEVDLNKSLKENTFLQEQLVELK--MLAE--EDKRKVSELTSKLKTTDEE 1215
Query: 375 IQQLEEDLKQTKRALQEQC-EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN 433
Q L+ +++ ++L+++ E K EL + + + + +E ++I + SK N
Sbjct: 1216 FQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTN 1275
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 84.2 bits (199), Expect = 1e-15
Identities = 85/384 (22%), Positives = 174/384 (45%), Gaps = 19/384 (4%)
Query: 134 ENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHL-SRYNDQGFELCGALRELKTQ 192
E E +E M +++ +K T ++ + + + + N Q EL +E + +
Sbjct: 602 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 661
Query: 193 AED-----AVNTVT-DLSKRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
ED ++ VT + +A HE+ L V A + L + + +++E+ +L
Sbjct: 662 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA--LSEMKSQYSKVLNELTQL 719
Query: 246 R----SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ ++ EN+ ++ E + RTA ++EK++ + L VAK++KQL E +
Sbjct: 720 KQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEK 779
Query: 302 ASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECK 361
A++T E E ++ A KL+ES+K E S+++Q +++EV + K
Sbjct: 780 AAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ----IRSEVSQVK 835
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
++ E + KS Q++ E L++ ++A +E E+ KR E + E + N + +
Sbjct: 836 REKENIQTLLKSKEQEVNELLQKFQQAQEELAEM-KRYAESSSKLEEDKDKKINEMSKEV 894
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ E S T +L+A ++ ++ ++++ CK++ + + L
Sbjct: 895 TKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLL 954
Query: 482 AAELLNKEEIIGKMQIQTRELIKN 505
A +E + K+ Q + KN
Sbjct: 955 YAVQGQMDEDVQKVLKQILTMCKN 978
Score = 52.0 bits (119), Expect = 7e-06
Identities = 93/477 (19%), Positives = 201/477 (42%), Gaps = 50/477 (10%)
Query: 222 VREVAKLRQDVETRNVMID-EIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTT 279
++++ ++ QD++ R + E ++L+ E ++ +A L + + E ++ L+ +KL T
Sbjct: 434 IQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLS--QKLKET 491
Query: 280 ESQLRQTRNRVAKMDKQ-------------------LREAEASITSLTGTVK-MLEDQSR 319
+S+ + V + KQ LR E I L ++ LE+ R
Sbjct: 492 QSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESER 551
Query: 320 QKEVQLEARARKLRESLKT---------GEVTTS--QLIQQRDSLQAEVLECKQQIEKLT 368
KE E + + T E+ +S +I+ + +A + E Q+ ++
Sbjct: 552 NKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEI 611
Query: 369 VQHKSAI-----QQLEEDLKQTKRALQEQC-EITKREIELKE---RTETELQD--SRNAI 417
++ K + Q+ ++ + K A+ E+ K+ EL + + EL+D R ++
Sbjct: 612 MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 671
Query: 418 EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR--EKESENKI 475
E++ A+ I + + L L K +E+T K+ + + EN +
Sbjct: 672 EDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 731
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
I + L + +M+ + L +++ E +V + E+ + + +A T A
Sbjct: 732 SITEHLQV-ITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKA-AMTDAMVPR 789
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
S L+ E+ L KL + V E++ + + E+ Q + ++K +E
Sbjct: 790 SSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKE 849
Query: 596 ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+ +N L K + ELA +++ E ++ ++ +K+I + E+ +L L + Q
Sbjct: 850 QEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 906
Score = 37.9 bits (84), Expect = 0.12
Identities = 55/253 (21%), Positives = 119/253 (47%), Gaps = 24/253 (9%)
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE- 470
D+ I++LQ + +L+K + + ER+ L ELQ+ + L C E
Sbjct: 429 DNDVRIQQLQEILQDLQKRLESSE--AERK-QLQVELQSRRAEL--------VCLNNTEI 477
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
SEN + QKL E +K E K + ++ +K ++ + + Y + +L+ I
Sbjct: 478 SENSSDLSQKLK-ETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHF-HELRVTEEEI 535
Query: 531 ANC-QESPNGISYQDLQQE-IMDLKMKLLD------VVHRNEELSEILAKKDQELEQQDK 582
Q+ N + + +E + +L+ KL++ + EE E+ + +E +K
Sbjct: 536 NVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNK 595
Query: 583 NSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHRM-RIVDEVNKQIAAKADEI 640
+ + +EE++ + +++ ++E + +D++ M R++DE+NKQ++ +
Sbjct: 596 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLY 655
Query: 641 QELFATLENKQQQ 653
+E A LE+ +++
Sbjct: 656 KEAQAELEDYRKR 668
>AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment
epithelial cell protein protein.
Length = 980
Score = 84.2 bits (199), Expect = 1e-15
Identities = 85/384 (22%), Positives = 174/384 (45%), Gaps = 19/384 (4%)
Query: 134 ENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHL-SRYNDQGFELCGALRELKTQ 192
E E +E M +++ +K T ++ + + + + N Q EL +E + +
Sbjct: 599 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 658
Query: 193 AED-----AVNTVT-DLSKRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
ED ++ VT + +A HE+ L V A + L + + +++E+ +L
Sbjct: 659 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA--LSEMKSQYSKVLNELTQL 716
Query: 246 R----SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ ++ EN+ ++ E + RTA ++EK++ + L VAK++KQL E +
Sbjct: 717 KQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEK 776
Query: 302 ASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECK 361
A++T E E ++ A KL+ES+K E S+++Q +++EV + K
Sbjct: 777 AAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ----IRSEVSQVK 832
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
++ E + KS Q++ E L++ ++A +E E+ KR E + E + N + +
Sbjct: 833 REKENIQTLLKSKEQEVNELLQKFQQAQEELAEM-KRYAESSSKLEEDKDKKINEMSKEV 891
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ E S T +L+A ++ ++ ++++ CK++ + + L
Sbjct: 892 TKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLL 951
Query: 482 AAELLNKEEIIGKMQIQTRELIKN 505
A +E + K+ Q + KN
Sbjct: 952 YAVQGQMDEDVQKVLKQILTMCKN 975
Score = 52.0 bits (119), Expect = 7e-06
Identities = 93/477 (19%), Positives = 201/477 (42%), Gaps = 50/477 (10%)
Query: 222 VREVAKLRQDVETRNVMID-EIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTT 279
++++ ++ QD++ R + E ++L+ E ++ +A L + + E ++ L+ +KL T
Sbjct: 431 IQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLS--QKLKET 488
Query: 280 ESQLRQTRNRVAKMDKQ-------------------LREAEASITSLTGTVK-MLEDQSR 319
+S+ + V + KQ LR E I L ++ LE+ R
Sbjct: 489 QSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESER 548
Query: 320 QKEVQLEARARKLRESLKT---------GEVTTS--QLIQQRDSLQAEVLECKQQIEKLT 368
KE E + + T E+ +S +I+ + +A + E Q+ ++
Sbjct: 549 NKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEI 608
Query: 369 VQHKSAI-----QQLEEDLKQTKRALQEQC-EITKREIELKE---RTETELQD--SRNAI 417
++ K + Q+ ++ + K A+ E+ K+ EL + + EL+D R ++
Sbjct: 609 MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 668
Query: 418 EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR--EKESENKI 475
E++ A+ I + + L L K +E+T K+ + + EN +
Sbjct: 669 EDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 728
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
I + L + +M+ + L +++ E +V + E+ + + +A T A
Sbjct: 729 SITEHLQV-ITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKA-AMTDAMVPR 786
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
S L+ E+ L KL + V E++ + + E+ Q + ++K +E
Sbjct: 787 SSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKE 846
Query: 596 ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+ +N L K + ELA +++ E ++ ++ +K+I + E+ +L L + Q
Sbjct: 847 QEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 903
Score = 37.9 bits (84), Expect = 0.12
Identities = 55/253 (21%), Positives = 119/253 (47%), Gaps = 24/253 (9%)
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE- 470
D+ I++LQ + +L+K + + ER+ L ELQ+ + L C E
Sbjct: 426 DNDVRIQQLQEILQDLQKRLESSE--AERK-QLQVELQSRRAEL--------VCLNNTEI 474
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
SEN + QKL E +K E K + ++ +K ++ + + Y + +L+ I
Sbjct: 475 SENSSDLSQKLK-ETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHF-HELRVTEEEI 532
Query: 531 ANC-QESPNGISYQDLQQE-IMDLKMKLLD------VVHRNEELSEILAKKDQELEQQDK 582
Q+ N + + +E + +L+ KL++ + EE E+ + +E +K
Sbjct: 533 NVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNK 592
Query: 583 NSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHRM-RIVDEVNKQIAAKADEI 640
+ + +EE++ + +++ ++E + +D++ M R++DE+NKQ++ +
Sbjct: 593 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLY 652
Query: 641 QELFATLENKQQQ 653
+E A LE+ +++
Sbjct: 653 KEAQAELEDYRKR 665
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 83.8 bits (198), Expect = 2e-15
Identities = 85/384 (22%), Positives = 174/384 (45%), Gaps = 19/384 (4%)
Query: 134 ENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHL-SRYNDQGFELCGALRELKTQ 192
E E +E M +++ +K T ++ + + + + N Q EL +E + +
Sbjct: 599 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 658
Query: 193 AED-----AVNTVT-DLSKRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
ED ++ VT + +A HE+ L V A + L + + +++E+ +L
Sbjct: 659 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA--LSEMKSQYSKVLNELTQL 716
Query: 246 R----SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ ++ EN+ ++ E + RTA ++EK++ + L VAK++KQL E +
Sbjct: 717 KQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEK 776
Query: 302 ASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECK 361
A++T E E ++ A KL+ES+K E S+++Q +++EV + K
Sbjct: 777 AAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ----IRSEVSQVK 832
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
++ E + KS Q++ E L++ ++A +E E+ KR E + E + N + +
Sbjct: 833 REKENIQTLLKSKEQEVNELLQKFQQAQEELAEM-KRYSESSSKLEEDKDKKINEMSKEV 891
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ E S T +L+A ++ ++ ++++ CK++ + + L
Sbjct: 892 TKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLL 951
Query: 482 AAELLNKEEIIGKMQIQTRELIKN 505
A +E + K+ Q + KN
Sbjct: 952 YAVQGQMDEDVQKVLKQILTMCKN 975
Score = 51.6 bits (118), Expect = 9e-06
Identities = 93/477 (19%), Positives = 201/477 (42%), Gaps = 50/477 (10%)
Query: 222 VREVAKLRQDVETRNVMID-EIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTT 279
++++ ++ QD++ R + E ++L+ E ++ +A L + + E ++ L+ +KL T
Sbjct: 431 IQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLS--QKLKET 488
Query: 280 ESQLRQTRNRVAKMDKQ-------------------LREAEASITSLTGTVK-MLEDQSR 319
+S+ + V + KQ LR E I L ++ LE+ R
Sbjct: 489 QSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESER 548
Query: 320 QKEVQLEARARKLRESLKT---------GEVTTS--QLIQQRDSLQAEVLECKQQIEKLT 368
KE E + + T E+ +S +I+ + +A + E Q+ ++
Sbjct: 549 NKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEI 608
Query: 369 VQHKSAI-----QQLEEDLKQTKRALQEQC-EITKREIELKE---RTETELQD--SRNAI 417
++ K + Q+ ++ + K A+ E+ K+ EL + + EL+D R ++
Sbjct: 609 MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 668
Query: 418 EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR--EKESENKI 475
E++ A+ I + + L L K +E+T K+ + + EN +
Sbjct: 669 EDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 728
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
I + L + +M+ + L +++ E +V + E+ + + +A T A
Sbjct: 729 SITEHLQV-ITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKA-AMTDAMVPR 786
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
S L+ E+ L KL + V E++ + + E+ Q + ++K +E
Sbjct: 787 SSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKE 846
Query: 596 ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+ +N L K + ELA +++ E ++ ++ +K+I + E+ +L L + Q
Sbjct: 847 QEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 903
Score = 37.9 bits (84), Expect = 0.12
Identities = 55/253 (21%), Positives = 119/253 (47%), Gaps = 24/253 (9%)
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE- 470
D+ I++LQ + +L+K + + ER+ L ELQ+ + L C E
Sbjct: 426 DNDVRIQQLQEILQDLQKRLESSE--AERK-QLQVELQSRRAEL--------VCLNNTEI 474
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
SEN + QKL E +K E K + ++ +K ++ + + Y + +L+ I
Sbjct: 475 SENSSDLSQKLK-ETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHF-HELRVTEEEI 532
Query: 531 ANC-QESPNGISYQDLQQE-IMDLKMKLLD------VVHRNEELSEILAKKDQELEQQDK 582
Q+ N + + +E + +L+ KL++ + EE E+ + +E +K
Sbjct: 533 NVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNK 592
Query: 583 NSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHRM-RIVDEVNKQIAAKADEI 640
+ + +EE++ + +++ ++E + +D++ M R++DE+NKQ++ +
Sbjct: 593 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLY 652
Query: 641 QELFATLENKQQQ 653
+E A LE+ +++
Sbjct: 653 KEAQAELEDYRKR 665
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 83.8 bits (198), Expect = 2e-15
Identities = 102/465 (21%), Positives = 203/465 (43%), Gaps = 35/465 (7%)
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-----RTAKLAIKEK 275
L++ AKL Q + +++ ++LR++ E K E ++ +E K I+EK
Sbjct: 1024 LIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEK 1083
Query: 276 LTTTESQLRQTRNRV-------AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
L E +L Q + R+ + K+++E +A I L ++ + E Q
Sbjct: 1084 LKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDL 1143
Query: 329 ARKLRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQT 385
AR+L E L+ TS I+ +AE + ++ +E+ T+QH++ L + +
Sbjct: 1144 ARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADS 1203
Query: 386 KRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLW 445
L EQ + +R +K++ E E + + I+++ + I L KSK N + D +
Sbjct: 1204 VAELGEQIDNLQR---VKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260
Query: 446 AELQATKETLRVTEDEVTTCKREKESEN-----KIGIQQKLAAELL-NKEEIIGKMQIQT 499
+E++A E ++ K +++N ++ ++ L ++L +K+ + +++
Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320
Query: 500 RELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGI--SYQDLQQEIMDLKMKL- 556
R++ + K + D QE+ + + E+ K K
Sbjct: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYE 1380
Query: 557 LDVVHRNEELSEI---LAKKDQELEQQDKNSRGQ-ARVIKIREELINVLKNKETEQSREL 612
D + R EEL E LA++ QE E++ + + + A + K ++ L +++ + R
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440
Query: 613 AALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
A L+ + R D+V + K DE Q A LE Q++ L
Sbjct: 1441 TAC-ATLDKKQRNFDKVLAEWKQKLDESQ---AELEAAQKESRSL 1481
Score = 73.3 bits (172), Expect = 3e-12
Identities = 101/482 (20%), Positives = 201/482 (41%), Gaps = 23/482 (4%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K E V +T+ + L+A L + + L++D++ + +
Sbjct: 907 ERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLT 966
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E L EE +KL KEK + E+ + + + DK L
Sbjct: 967 KVEKEKHATENKVKNLSEEMTAL-EENISKLT-KEKKSLQEAHQQTLDDLQVEEDKVNGL 1024
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ A + T ++ +Q ++ LE RKL LK + + L ++ ++ ++
Sbjct: 1025 IKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKL 1084
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTK-RALQEQCEITKREIELKERTETELQDSRNA 416
K++ E +Q + +Q+ Q K + LQ + E + EIE + +++ R+
Sbjct: 1085 K--KKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSD 1142
Query: 417 I-EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESEN 473
+ EL+ LE++ E AE Q + L + E T K+ +
Sbjct: 1143 LARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQAD 1202
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
+ +L ++ N + + K++ + EL I + E + RT
Sbjct: 1203 SVA---ELGEQIDNLQRVKQKLEKEKSELKMEI---DDMASNIEALSKSKSNIERTCRTV 1256
Query: 534 QESPNGISYQDLQQE--IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
++ + I +D QQ I DL M+ + +N ELS + +K+ + Q K+ + + +
Sbjct: 1257 EDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQL 1316
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
EEL ++ +ET+ +A Q H ++ E ++ E+Q + ++
Sbjct: 1317 ---EELKRQME-EETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEV 1372
Query: 652 QQ 653
Q
Sbjct: 1373 AQ 1374
Score = 68.1 bits (159), Expect = 1e-10
Identities = 86/399 (21%), Positives = 182/399 (45%), Gaps = 37/399 (9%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
++++ T + +T+ +A+ + + +E E + SL + E Q +VQ E
Sbjct: 850 EKEMATMKEDFERTKEELARSEARRKELEEKMVSL-----LQEKNDLQLQVQSET----- 899
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
E+L E LI+ + L+A+V E +++E+ +++ +L KR L+++
Sbjct: 900 -ENLMDAEERCEGLIKSKILLEAKVKELTERLEEE--------EEMNSELVAKKRNLEDK 950
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKII-ELEKSKPNPDLPTEREIDLWAELQAT 451
C KR+I+ E T T+++ ++A E + E+ + N T+ + L Q T
Sbjct: 951 CSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQT 1010
Query: 452 KETLRVTEDEVT-----TCKREKES---ENKIGIQQKLAAELLN-KEEIIGKMQIQTREL 502
+ L+V ED+V K E+++ E + ++KL A+L K ++ G +++ ++E
Sbjct: 1011 LDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKM-SQES 1069
Query: 503 IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
I +++ NE++ I+ + ++ + E + + +Q +E+ +L + +
Sbjct: 1070 IMDLE-NEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEA 1128
Query: 563 NEELSEILAKKDQELEQQ-DKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ-DLE 620
L + K+ +L ++ ++ S I + K +E E + L++ L+
Sbjct: 1129 EHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1188
Query: 621 HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
H KQ AD + EL ++N Q+ +LEK
Sbjct: 1189 HEATAATLRKKQ----ADSVAELGEQIDNLQRVKQKLEK 1223
Score = 64.5 bits (150), Expect = 1e-09
Identities = 88/433 (20%), Positives = 191/433 (44%), Gaps = 31/433 (7%)
Query: 112 VADWTAQ-EVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTD--GDI 168
+A+W + + +Q +A + + EL E ++ +T N++ + D+
Sbjct: 1457 LAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDL 1516
Query: 169 LEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKL 228
E ++ E + ++ + D + ++ HE ++ V L + ++L
Sbjct: 1517 TEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL 1576
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE---RTAKLAIKEK----LTTTES 281
+ V ++ +EI +L+ S+ +A E ++ LD E R L +K+K L E
Sbjct: 1577 DRKVIEKD---EEIEQLKRNSQ--RAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEI 1631
Query: 282 QLRQTRNRVAKMDKQLREAEASITS----LTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
QL + ++A+ + LR + + L ++ ED Q + +E R L E L+
Sbjct: 1632 QLGHSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAI-VERRNGLLLEELE 1690
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI---QQLEEDLKQTKRALQEQCE 394
+V Q + R + E+L+ +++ L Q+ S I ++LE D+ Q + ++ +
Sbjct: 1691 EMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQ 1750
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKE 453
++ E ++ T+ +++ Q LE+ K N + + DL L +A +
Sbjct: 1751 ESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK---DLQHRLDEAEQL 1807
Query: 454 TLRVTEDEVTTCK-REKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQK 512
L+ + ++ + R +E EN++ ++QK AE L K + + +E+ + + +
Sbjct: 1808 ALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAH---KYERKVKEMTYQAEEDRKN 1864
Query: 513 VIQYEQYVRDLQA 525
+++ + V LQA
Sbjct: 1865 ILRLQDLVDKLQA 1877
Score = 63.7 bits (148), Expect = 2e-09
Identities = 87/415 (20%), Positives = 180/415 (43%), Gaps = 38/415 (9%)
Query: 256 EEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE 315
E + EL + ++EK+ + + + +V + L +AE L
Sbjct: 861 ERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLI------- 913
Query: 316 DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTV------ 369
+ ++ LEA+ ++L E L+ E S+L+ ++ +L+ + K+ I+ L +
Sbjct: 914 ----KSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVE 969
Query: 370 QHKSAIQQLEEDLKQTKRALQEQ-CEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
+ K A + ++L + AL+E ++TK + L+E + L D + +EE K+ L
Sbjct: 970 KEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQ--VEE--DKVNGLI 1025
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELL 486
K + T+ DL L+ K+ LR ++ KR+ E + K+ + L E
Sbjct: 1026 KINAKLEQQTD---DLEGSLEQEKK-LRA---DLERAKRKLEGDLKMSQESIMDLENEKQ 1078
Query: 487 NKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
EE + K + + +L I + +Q+++ +++LQA + E+ + + + ++
Sbjct: 1079 QIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAK-IE 1137
Query: 547 QEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRGQARVIKIREELINVL 601
++ DL +L ++ R EE S +I K +E E Q K R E L
Sbjct: 1138 KQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQ-KMRRDLEEATLQHEATAATL 1196
Query: 602 KNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ K+ + EL +L+ + +++ ++ + D++ L + I R
Sbjct: 1197 RKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIER 1251
Score = 52.0 bits (119), Expect = 7e-06
Identities = 89/447 (19%), Positives = 185/447 (41%), Gaps = 32/447 (7%)
Query: 224 EVAKLRQDVETRNVM-IDEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTES 281
EVA+ + ET + +E+ E + + E + E + A L K++L
Sbjct: 1371 EVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVE 1430
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEV 341
L + R L + + + + K D+S+ + + +R L L
Sbjct: 1431 DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRN 1490
Query: 342 TTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE 401
+++ Q ++L+ E +++I LT Q + L+E K K QE+ ++ ++
Sbjct: 1491 AYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDL---QVA 1547
Query: 402 LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDE 461
L+E E L+ + I +Q ++ +++ + + EI+ Q + + R E
Sbjct: 1548 LEE-VEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIE-----QLKRNSQRAAEAL 1601
Query: 462 VTTCKREKESEN-KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYV 520
+ E S N + +++K+ +L E +G Q E ++++ + ++ + ++
Sbjct: 1602 QSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHL 1661
Query: 521 RDLQAHNRTIAN---CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL 577
D N + E NG+ L +E+ ++K+ L+ R LSE QEL
Sbjct: 1662 DDALRSNEDLKEQLAIVERRNGL----LLEELEEMKV-ALEQTERTRRLSE------QEL 1710
Query: 578 EQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI---A 634
D + R Q + LIN K E + ++ A ++ ++ ++ K I A
Sbjct: 1711 --LDASDRVQL-LHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAA 1767
Query: 635 AKADEIQELFATLENKQQQIHRLEKIV 661
A+E+++ T + ++ LE+ V
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNLEQTV 1794
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 83.8 bits (198), Expect = 2e-15
Identities = 85/384 (22%), Positives = 174/384 (45%), Gaps = 19/384 (4%)
Query: 134 ENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHL-SRYNDQGFELCGALRELKTQ 192
E E +E M +++ +K T ++ + + + + N Q EL +E + +
Sbjct: 608 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 667
Query: 193 AED-----AVNTVT-DLSKRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
ED ++ VT + +A HE+ L V A + L + + +++E+ +L
Sbjct: 668 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA--LSEMKSQYSKVLNELTQL 725
Query: 246 R----SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ ++ EN+ ++ E + RTA ++EK++ + L VAK++KQL E +
Sbjct: 726 KQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEK 785
Query: 302 ASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECK 361
A++T E E ++ A KL+ES+K E S+++Q +++EV + K
Sbjct: 786 AAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQ----IRSEVSQVK 841
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
++ E + KS Q++ E L++ ++A +E E+ KR E + E + N + +
Sbjct: 842 REKENIQTLLKSKEQEVNELLQKFQQAQEELAEM-KRYSESSSKLEEDKDKKINEMSKEV 900
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ E S T +L+A ++ ++ ++++ CK++ + + L
Sbjct: 901 TKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLL 960
Query: 482 AAELLNKEEIIGKMQIQTRELIKN 505
A +E + K+ Q + KN
Sbjct: 961 YAVQGQMDEDVQKVLKQILTMCKN 984
Score = 51.6 bits (118), Expect = 9e-06
Identities = 93/477 (19%), Positives = 201/477 (42%), Gaps = 50/477 (10%)
Query: 222 VREVAKLRQDVETRNVMID-EIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTT 279
++++ ++ QD++ R + E ++L+ E ++ +A L + + E ++ L+ +KL T
Sbjct: 440 IQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLS--QKLKET 497
Query: 280 ESQLRQTRNRVAKMDKQ-------------------LREAEASITSLTGTVK-MLEDQSR 319
+S+ + V + KQ LR E I L ++ LE+ R
Sbjct: 498 QSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESER 557
Query: 320 QKEVQLEARARKLRESLKT---------GEVTTS--QLIQQRDSLQAEVLECKQQIEKLT 368
KE E + + T E+ +S +I+ + +A + E Q+ ++
Sbjct: 558 NKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEI 617
Query: 369 VQHKSAI-----QQLEEDLKQTKRALQEQC-EITKREIELKE---RTETELQD--SRNAI 417
++ K + Q+ ++ + K A+ E+ K+ EL + + EL+D R ++
Sbjct: 618 MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 677
Query: 418 EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR--EKESENKI 475
E++ A+ I + + L L K +E+T K+ + + EN +
Sbjct: 678 EDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 737
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
I + L + +M+ + L +++ E +V + E+ + + +A T A
Sbjct: 738 SITEHLQV-ITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKA-AMTDAMVPR 795
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
S L+ E+ L KL + V E++ + + E+ Q + ++K +E
Sbjct: 796 SSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKE 855
Query: 596 ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+ +N L K + ELA +++ E ++ ++ +K+I + E+ +L L + Q
Sbjct: 856 QEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 912
Score = 37.9 bits (84), Expect = 0.12
Identities = 55/253 (21%), Positives = 119/253 (47%), Gaps = 24/253 (9%)
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE- 470
D+ I++LQ + +L+K + + ER+ L ELQ+ + L C E
Sbjct: 435 DNDVRIQQLQEILQDLQKRLESSE--AERK-QLQVELQSRRAEL--------VCLNNTEI 483
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
SEN + QKL E +K E K + ++ +K ++ + + Y + +L+ I
Sbjct: 484 SENSSDLSQKLK-ETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHF-HELRVTEEEI 541
Query: 531 ANC-QESPNGISYQDLQQE-IMDLKMKLLD------VVHRNEELSEILAKKDQELEQQDK 582
Q+ N + + +E + +L+ KL++ + EE E+ + +E +K
Sbjct: 542 NVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNK 601
Query: 583 NSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHRM-RIVDEVNKQIAAKADEI 640
+ + +EE++ + +++ ++E + +D++ M R++DE+NKQ++ +
Sbjct: 602 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLY 661
Query: 641 QELFATLENKQQQ 653
+E A LE+ +++
Sbjct: 662 KEAQAELEDYRKR 674
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 81.8 bits (193), Expect = 7e-15
Identities = 94/471 (19%), Positives = 210/471 (44%), Gaps = 29/471 (6%)
Query: 192 QAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESEN 251
+ +D+ + + + R + V L ++ +L+ R+++ ++ +E +
Sbjct: 457 ELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSS 516
Query: 252 TK-ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNR-----VAKMDKQLREAEASIT 305
K +LE+ R E+ +E L + + +L++ + + V +M + + E +
Sbjct: 517 LKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLV 576
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
S + E + R+ + E RK E +L++ +D + EV E + +E
Sbjct: 577 SARRRSDLYESELRESRLAAEEFKRKATEC-------QHKLLKAKDQGKPEVGEYAK-LE 628
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE---LQDSRNAIEELQA 422
K+ + + IQ+L+E L++ +A E E+ + + KER E E LQ+ ++ E ++
Sbjct: 629 KINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRK 688
Query: 423 KII---ELEKSKPNPDLPTER-EIDLWAELQATKETLRVTEDEVTTCKREKES-ENKIGI 477
K++ ELE+ + + E+ L + Q +E ++V ++++ +KE+ EN +
Sbjct: 689 KLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLEN---M 745
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
Q+ E K +I+ + + + I+ EQ++++ + L A++
Sbjct: 746 MQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSE-ANKLAANSSLFTQRNMKA 804
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+L+Q+ L+ + + +N +L E L K + + DKN + ++RE
Sbjct: 805 QEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQ-DHSDKNRLLELET-RLREVS 862
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
+ + ++ E R+L LQ L+ R + + AA ++++ LE
Sbjct: 863 LE-HEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELE 912
Score = 66.1 bits (154), Expect = 4e-10
Identities = 103/560 (18%), Positives = 238/560 (42%), Gaps = 41/560 (7%)
Query: 117 AQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHL-SRY 175
A+E+ + +R+A S+ + L + E IK + +D D + LE++ R+
Sbjct: 693 AEELEEKHREAQVSAQ-HLEVHLKQKEQHYEEKIKVLDNQ--IKKDLADKETLENMMQRH 749
Query: 176 NDQGFELCGALRELKTQAEDAVNTVTDLSKRACH--ERRTLIAVGEALVREVAKLRQDV- 232
++ E L E K + + L +R E L A + K ++++
Sbjct: 750 EEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMI 809
Query: 233 -ETRNVMID-EIRELRSESENTKA---LEEMRHELDEERTAKLAIKEKLTTT----ESQL 283
E R E + + E++N K LE++ H+ ++ L ++ +L E Q
Sbjct: 810 SELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQK 869
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
+ + ++ ++ L+E E+ +T+L LE Q RQ + +LE + E ++
Sbjct: 870 LELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHR 929
Query: 344 SQLIQQRDSLQ---AEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQE------ 391
++ ++ D+L+ + + ++Q+ +LT + Q L + L + A E
Sbjct: 930 DEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRS 989
Query: 392 -----QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
+ EIT+RE++L + +T ++ + L+ ++++LE + + L ER+ + W
Sbjct: 990 EVDHLRREITEREMQLTSQKQT-MEALKTTCTMLEEQVMDLE-ALNDELLEKERQWEAWR 1047
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
+ +++ + E +++ Q++ E + + + + L + +
Sbjct: 1048 SVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQAL 1107
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL 566
K + K + DL+ + + N S Q + +LK +LL+ + ++
Sbjct: 1108 KEQKLKAESLSDKLNDLEKKHAML-----EMNARSLQQKLETERELKQRLLEEQAKLQQQ 1162
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKI-REELINVLKNKETEQSRELAALQQDLEHRMRI 625
++ L Q + + +A ++K R +L L+N + S E ++ + + ++
Sbjct: 1163 MDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKL 1222
Query: 626 VDEVNKQIAAKADEIQELFA 645
+D + ++ A + + LF+
Sbjct: 1223 IDFLQAKMDQPAKKKKGLFS 1242
Score = 34.3 bits (75), Expect = 1.5
Identities = 53/278 (19%), Positives = 121/278 (43%), Gaps = 21/278 (7%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
AL+ T E+ V + L+ + R A L E ++ V M+D ++
Sbjct: 1014 ALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQ 1073
Query: 245 LRSESEN--TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
R+ ++ T++ + + + E + LA+++ L + + +++ ++K+ E
Sbjct: 1074 SRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEM 1133
Query: 303 SITSLTGTV--------KMLEDQSR-QKEVQLEAR-----ARKLRESLKTGEVTT---SQ 345
+ SL + ++LE+Q++ Q+++ L+ + L+E+L ++ S
Sbjct: 1134 NARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSD 1193
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
L Q +++Q K ++E Q I L+ + Q + + K + L +
Sbjct: 1194 LEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQ 1253
Query: 406 TETELQDSRNAIEELQAKIIELEKS--KPNPDLPTERE 441
+ + + A+E+ +A+ ELE++ K +L + RE
Sbjct: 1254 VPLQYNELKLALEKEKARCAELEEALQKTRIELRSARE 1291
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 81.4 bits (192), Expect = 1e-14
Identities = 100/457 (21%), Positives = 207/457 (45%), Gaps = 32/457 (7%)
Query: 225 VAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
+A+L ++ +N + +IREL S+ + L+ R ++ K + E+L +++L
Sbjct: 5 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 64
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
T + A + + E +T L K L++++R E Q++ +K +++ E T
Sbjct: 65 EDTLDSTATQQELRAKREQEVTVLK---KALDEETRSHEAQVQEMRQKHAQAV---EELT 118
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQ---QLEEDLKQTKRALQEQCEITKREI 400
QL +Q +A + + KQ +EK ++ Q +++++ K+ L+ Q + + +
Sbjct: 119 EQL-EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 177
Query: 401 ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTE 459
ER EL D + ++ + + + +++ L ++LQ T+E L+
Sbjct: 178 SDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEET 237
Query: 460 DE---VTTCKREKESENKIGIQQKLAAELLNKEEI---IGKMQIQTRELIKNIKLNEQKV 513
+ V+T R+ E E +Q +L E+ K+ + I + IQ + K ++ V
Sbjct: 238 RQKLNVSTKLRQLEEERN-SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 296
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV---HRNEELSEIL 570
E+ + Q + Q +Y L++ L+ +L D+V +L L
Sbjct: 297 EALEEGKKRFQKEIENLTQ-QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL 355
Query: 571 AKKDQELEQ---QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
KK ++ +Q ++KN + + R E + KET+ AL++ LE + + +
Sbjct: 356 EKKQRKFDQLLAEEKNISSKYADERDRAEA--EAREKETKALSLARALEEALEAKEEL-E 412
Query: 628 EVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
NK + A E+++L ++ ++ + +H LEK AL
Sbjct: 413 RTNKMLKA---EMEDLVSSKDDVGKNVHELEKSKRAL 446
Score = 74.5 bits (175), Expect = 1e-12
Identities = 113/542 (20%), Positives = 222/542 (40%), Gaps = 47/542 (8%)
Query: 162 DQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL 221
++ ++ + + + ++ + G L E + +A V LS + + L
Sbjct: 181 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 240
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTE 280
+ KLRQ E RN + D++ E +N + + + +L + + + E
Sbjct: 241 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 300
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLE----------DQSRQKEVQLEARAR 330
++ + + + +Q E A+ L T L+ D RQ LE + R
Sbjct: 301 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQR 360
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K + L + +S+ +RD +AE E + + L + A+ + +E+L++T + L+
Sbjct: 361 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLK 419
Query: 391 EQCE--------ITKREIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD---- 435
+ E + K EL K ET++++ + +EEL+ ++ E +K +
Sbjct: 420 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 479
Query: 436 -LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKE 489
L + E DL A + +E R + ++ + E E E K ++KL +L + E
Sbjct: 480 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 539
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQE 548
E IK ++ + ++ +++ + D +A + A +E N + L+ +
Sbjct: 540 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEAD 597
Query: 549 IMDLKMKLLDVVH-------RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINV 600
+M L+ L EEL+E LA QD+ R +AR+ ++ EEL
Sbjct: 598 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 657
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEK 659
N E R A QQ + + E + A K + Q+L + + ++H +E
Sbjct: 658 QGNMEAMSDRVRKATQQAEQLSNELATE--RSTAQKNESSRQQLERQNKELRSKLHEMEG 715
Query: 660 IV 661
V
Sbjct: 716 AV 717
Score = 52.0 bits (119), Expect = 7e-06
Identities = 50/208 (24%), Positives = 99/208 (47%), Gaps = 16/208 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELDE--ERTAKLAIKEKLTT--TESQLR 284
++ +E R ++E EL E N +A+ + + + E+ + E+ T ES +
Sbjct: 640 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQ 697
Query: 285 QTRNRVAKMDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
Q + ++ +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 698 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 752
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 753 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 809
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSK 431
+ + EL ++ + E + ++ L KSK
Sbjct: 810 RKLQRELDEATESNEAMGREVNAL-KSK 836
Score = 49.2 bits (112), Expect = 5e-05
Identities = 44/204 (21%), Positives = 97/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 582 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 636
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 637 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 692
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E + QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 693 ESSRQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 752
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 753 LKQKDKKLKEILLQVEDERKMAEQ 776
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 81.4 bits (192), Expect = 1e-14
Identities = 116/576 (20%), Positives = 251/576 (43%), Gaps = 35/576 (6%)
Query: 103 LPQELILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQD 162
+ +E++L + + +L D IA E + +L +E +N+ K + Q+
Sbjct: 983 MEEEILLLEDQNSKFIKEKKLMEDRIA----ECSSQLAEEEEKAKNLAK-----IRNKQE 1033
Query: 163 QTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV 222
D+ E L + EL A R+L + D + + +L + + L E L
Sbjct: 1034 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093
Query: 223 REVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
+A+ + +N + +REL+++ +E + E + ++ K + E+L ++
Sbjct: 1094 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT 1153
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEV 341
+L T + A + + E + L K LE++++ E Q++ +R+ T
Sbjct: 1154 ELEDTLDTTAAQQELRTKREQEVAELK---KALEEETKNHEAQIQ----DMRQRHATALE 1206
Query: 342 TTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
S+ ++Q +A + + KQ +E K +QQ++ + + ++ L Q +
Sbjct: 1207 ELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA 1266
Query: 399 EIELKERTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +R EL + + ++ EL LE+++ + L ++LQ T+E L+
Sbjct: 1267 KVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE 1326
Query: 458 -TEDEVTTCKREK---ESENKIGIQQKLAAELL-NKEEIIGKMQIQTRELIKNIKLNEQK 512
T ++ R + E +N + QQ+ E N E+ + +Q Q + K + +
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1386
Query: 513 VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV---VHRNEELSEI 569
+ E+ + L ++ E ++Y L++ L+ +L D+ + +++
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLEE-KALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASN 1445
Query: 570 LAKKDQELEQQDKNSRG-QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK ++ +Q + AR + R+ + KET+ AL++ LE + +
Sbjct: 1446 LEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF-ER 1504
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
NKQ+ A ++++L ++ ++ + +H LEK AL
Sbjct: 1505 QNKQLRA---DMEDLMSSKDDVGKNVHELEKSKRAL 1537
Score = 70.5 bits (165), Expect = 2e-11
Identities = 105/518 (20%), Positives = 218/518 (42%), Gaps = 48/518 (9%)
Query: 172 LSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQD 231
L +G + L++Q +D + + +++ + + + E + ++
Sbjct: 1296 LEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEE 1355
Query: 232 VETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
E R + ++ L+S+ +TK +++ ++ AK + + +L +
Sbjct: 1356 EEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAY 1415
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
K++K + + LT + D RQ LE + +K + L + +++ ++R
Sbjct: 1416 DKLEKTKNRLQQELDDLTVDL----DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEER 1471
Query: 351 DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITK-------REIE 401
D +AE E + + L + A++ EE +Q K RA E +K E+E
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELE 1531
Query: 402 LKERT-ETELQDSRNAIEELQAKIIELEKSKPNPD-----LPTEREIDLWAELQATKETL 455
+R E ++++ R +EEL+ ++ E +K + + + E DL + +E
Sbjct: 1532 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKK 1591
Query: 456 RVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
R+ +V + E E E K + ++K+ +L + E I E+IK ++ +
Sbjct: 1592 RLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQ 1651
Query: 511 QKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQEIMDLKMKLLD--------VVH 561
++ Y++ + + +A + A +ES + + L+ EI+ L+ +L
Sbjct: 1652 AQMKDYQRELEEARASRDEIFAQSKESEKKL--KSLEAEILQLQEELASSERARRHAEQE 1709
Query: 562 RNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEH 621
R+E EI + D+ R +AR+ ++ EEL E EQS + L
Sbjct: 1710 RDELADEITNSASGKSALLDEKRRLEARIAQLEEEL-------EEEQS-NMELLNDRFRK 1761
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
VD +N ++AA+ Q+ +N +QQ+ R K
Sbjct: 1762 TTLQVDTLNAELAAERSAAQK----SDNARQQLERQNK 1795
Score = 67.7 bits (158), Expect = 1e-10
Identities = 100/454 (22%), Positives = 199/454 (43%), Gaps = 31/454 (6%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L E K++ ++ +DE R + + K E + + EE L +
Sbjct: 939 QILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFI 998
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL---EARARKLRES 335
E +L + +R+A+ QL E E +L E E +L E ++L ++
Sbjct: 999 KEKKLME--DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1056
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
+ + T+ L Q LQA++ E K Q+ K + + A+ + +++ AL+ E+
Sbjct: 1057 KRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVREL 1116
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ EL+E E+E + SRN E+ + + E ++ L TE E L + A ++ L
Sbjct: 1117 QAQIAELQEDFESE-KASRNKAEKQKRDLSEELEA-----LKTELEDTL--DTTAAQQEL 1168
Query: 456 RV-TEDEVTTCKREKESENK---IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQ 511
R E EV K+ E E K IQ EE+ +++ Q + N++ N+Q
Sbjct: 1169 RTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE-QAKRFKANLEKNKQ 1227
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILA 571
+ E ++L + + ++ + + L ++ +L K+ + EL+E +
Sbjct: 1228 GL---ETDNKELACEVKVLQQV-KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKAS 1283
Query: 572 KKDQELEQ-QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVN 630
K EL+ + + IK ++ ++ + + ++EL LQ++ ++ + +
Sbjct: 1284 KLQNELDNVSTLLEEAEKKGIKFAKDAASL--ESQLQDTQEL--LQEETRQKLNLSSRI- 1338
Query: 631 KQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
+Q+ + + +QE E +++ LEK VLAL
Sbjct: 1339 RQLEEEKNSLQE---QQEEEEEARKNLEKQVLAL 1369
Score = 67.3 bits (157), Expect = 2e-10
Identities = 83/413 (20%), Positives = 180/413 (43%), Gaps = 27/413 (6%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQ---LREAEASITSLTGTVKMLEDQ 317
EL + L +KEK T E +L + + ++ ++ L E + T L + + +
Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRAR 912
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
K+ +LE L ++ E L ++ +QA + + ++Q+++ + Q
Sbjct: 913 LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL--Q 970
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
LE+ + K E+ + + K E +L + R I E +++ E E+ N
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR--IAECSSQLAEEEEKAKNLAKI 1028
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
++ + ++L+ + T E+ KR+ + E +Q ++A +E+ ++
Sbjct: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET-TDLQDQIAELQAQIDELKLQLAK 1087
Query: 498 QTRELIKNIKLNEQKVIQYE---QYVRDLQAHNRTIANCQESPNGI------SYQDLQQE 548
+ EL + + + + + VR+LQA + ES +DL +E
Sbjct: 1088 KEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEE 1147
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQE-------LEQQDKNSRGQARVIKIREELINVL 601
+ LK +L D + E+ K++QE LE++ KN Q + ++ R
Sbjct: 1148 LEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEE 1207
Query: 602 KNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+++ EQ++ A +LE + ++ NK++A + +Q++ A E+K++++
Sbjct: 1208 LSEQLEQAKRFKA---NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1257
Score = 58.8 bits (136), Expect = 6e-08
Identities = 108/546 (19%), Positives = 240/546 (43%), Gaps = 56/546 (10%)
Query: 154 KTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRT 213
+T +N + E + +Q E A + L+ Q + + D K+ + T
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1386
Query: 214 LIAVGEA---LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
+ ++ EA L+++ L Q +E + + D++ + ++ + + L+++ +LD +R
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQ--QELDDLTVDLDHQRQVAS 1444
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI----TSLTGTVKMLEDQSRQKEVQLE 326
+++K + L + ++ A+ ++ AEA T + LE+ KE + E
Sbjct: 1445 NLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE-EFE 1503
Query: 327 ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK 386
+ ++LR ++ + + + L+ +QQ+E++ Q +++LE++L+ T+
Sbjct: 1504 RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ----LEELEDELQATE 1559
Query: 387 RA---LQEQCEITKREIE--LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT--- 438
A L+ + K + E L+ R E + R I++++ ELE + L
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1619
Query: 439 -EREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
+ EIDL +L+A E DEV R+ +++ K Q++L +++EI + +
Sbjct: 1620 KKMEIDL-KDLEAQIEAANKARDEVIKQLRKLQAQMK-DYQRELEEARASRDEIFAQSKE 1677
Query: 498 QTREL----IKNIKLNEQ-----KVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE 548
++L + ++L E+ + ++ + RD A T + +S + L+
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEAR 1737
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELE-------------QQDKNSRGQA----RVI 591
I L+ +L + E L++ K +++ Q+ N+R Q + +
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 592 KIR-EELINVLKNKETEQSRELAA----LQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
K + +EL +K+K L A L++ LE + NK + +++E+F
Sbjct: 1798 KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQ 1857
Query: 647 LENKQQ 652
+E++++
Sbjct: 1858 VEDERR 1863
Score = 51.2 bits (117), Expect = 1e-05
Identities = 41/191 (21%), Positives = 89/191 (46%), Gaps = 7/191 (3%)
Query: 242 IRELRSESENTKALEEMRHELDEERTAKL-AIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
I +L E E ++ E+ ++ + T ++ + +L S +++ N ++++Q +E
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDSLQAEV 357
+A + L G VK + + LEA+ +L E L+ ++L+++ + E+
Sbjct: 1798 KAKLQELEGAVK---SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEI 1854
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ + Q+K +++ +KQ KR L+E E R + + + EL D+ A
Sbjct: 1855 FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1914
Query: 418 EELQAKIIELE 428
E L ++ L+
Sbjct: 1915 EGLSREVSTLK 1925
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/210 (23%), Positives = 103/210 (49%), Gaps = 21/210 (10%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
+E K + +E + + E EL S + E+ R EL +E T + K L +
Sbjct: 1676 KESEKKLKSLEAEILQLQE--ELASSERARRHAEQERDELADEITNSASGKSALL---DE 1730
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTG 339
R+ R+A+++++L E ++++ ++L D+ R+ +Q++ +L R + +
Sbjct: 1731 KRRLEARIAQLEEELEEEQSNM-------ELLNDRFRKTTLQVDTLNAELAAERSAAQKS 1783
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
+ QL +Q L+A++ E + ++ K T+ A I QLEE L+Q + ++
Sbjct: 1784 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL 1843
Query: 396 TKR-EIELKERTETELQDSRNAIEELQAKI 424
+R E +LKE +++D R ++ + ++
Sbjct: 1844 VRRTEKKLKE-IFMQVEDERRHADQYKEQM 1872
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 81.4 bits (192), Expect = 1e-14
Identities = 116/576 (20%), Positives = 251/576 (43%), Gaps = 35/576 (6%)
Query: 103 LPQELILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQD 162
+ +E++L + + +L D IA E + +L +E +N+ K + Q+
Sbjct: 983 MEEEILLLEDQNSKFIKEKKLMEDRIA----ECSSQLAEEEEKAKNLAK-----IRNKQE 1033
Query: 163 QTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV 222
D+ E L + EL A R+L + D + + +L + + L E L
Sbjct: 1034 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093
Query: 223 REVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
+A+ + +N + +REL+++ +E + E + ++ K + E+L ++
Sbjct: 1094 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT 1153
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEV 341
+L T + A + + E + L K LE++++ E Q++ +R+ T
Sbjct: 1154 ELEDTLDTTAAQQELRTKREQEVAELK---KALEEETKNHEAQIQ----DMRQRHATALE 1206
Query: 342 TTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
S+ ++Q +A + + KQ +E K +QQ++ + + ++ L Q +
Sbjct: 1207 ELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA 1266
Query: 399 EIELKERTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +R EL + + ++ EL LE+++ + L ++LQ T+E L+
Sbjct: 1267 KVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE 1326
Query: 458 -TEDEVTTCKREK---ESENKIGIQQKLAAELL-NKEEIIGKMQIQTRELIKNIKLNEQK 512
T ++ R + E +N + QQ+ E N E+ + +Q Q + K + +
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1386
Query: 513 VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV---VHRNEELSEI 569
+ E+ + L ++ E ++Y L++ L+ +L D+ + +++
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLEE-KALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASN 1445
Query: 570 LAKKDQELEQQDKNSRG-QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK ++ +Q + AR + R+ + KET+ AL++ LE + +
Sbjct: 1446 LEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF-ER 1504
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
NKQ+ A ++++L ++ ++ + +H LEK AL
Sbjct: 1505 QNKQLRA---DMEDLMSSKDDVGKNVHELEKSKRAL 1537
Score = 70.5 bits (165), Expect = 2e-11
Identities = 105/518 (20%), Positives = 218/518 (42%), Gaps = 48/518 (9%)
Query: 172 LSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQD 231
L +G + L++Q +D + + +++ + + + E + ++
Sbjct: 1296 LEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEE 1355
Query: 232 VETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
E R + ++ L+S+ +TK +++ ++ AK + + +L +
Sbjct: 1356 EEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAY 1415
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
K++K + + LT + D RQ LE + +K + L + +++ ++R
Sbjct: 1416 DKLEKTKNRLQQELDDLTVDL----DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEER 1471
Query: 351 DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITK-------REIE 401
D +AE E + + L + A++ EE +Q K RA E +K E+E
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELE 1531
Query: 402 LKERT-ETELQDSRNAIEELQAKIIELEKSKPNPD-----LPTEREIDLWAELQATKETL 455
+R E ++++ R +EEL+ ++ E +K + + + E DL + +E
Sbjct: 1532 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKK 1591
Query: 456 RVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
R+ +V + E E E K + ++K+ +L + E I E+IK ++ +
Sbjct: 1592 RLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQ 1651
Query: 511 QKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQEIMDLKMKLLD--------VVH 561
++ Y++ + + +A + A +ES + + L+ EI+ L+ +L
Sbjct: 1652 AQMKDYQRELEEARASRDEIFAQSKESEKKL--KSLEAEILQLQEELASSERARRHAEQE 1709
Query: 562 RNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEH 621
R+E EI + D+ R +AR+ ++ EEL E EQS + L
Sbjct: 1710 RDELADEITNSASGKSALLDEKRRLEARIAQLEEEL-------EEEQS-NMELLNDRFRK 1761
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
VD +N ++AA+ Q+ +N +QQ+ R K
Sbjct: 1762 TTLQVDTLNAELAAERSAAQK----SDNARQQLERQNK 1795
Score = 67.7 bits (158), Expect = 1e-10
Identities = 100/454 (22%), Positives = 199/454 (43%), Gaps = 31/454 (6%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L E K++ ++ +DE R + + K E + + EE L +
Sbjct: 939 QILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFI 998
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL---EARARKLRES 335
E +L + +R+A+ QL E E +L E E +L E ++L ++
Sbjct: 999 KEKKLME--DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1056
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
+ + T+ L Q LQA++ E K Q+ K + + A+ + +++ AL+ E+
Sbjct: 1057 KRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVREL 1116
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ EL+E E+E + SRN E+ + + E ++ L TE E L + A ++ L
Sbjct: 1117 QAQIAELQEDFESE-KASRNKAEKQKRDLSEELEA-----LKTELEDTL--DTTAAQQEL 1168
Query: 456 RV-TEDEVTTCKREKESENK---IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQ 511
R E EV K+ E E K IQ EE+ +++ Q + N++ N+Q
Sbjct: 1169 RTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE-QAKRFKANLEKNKQ 1227
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILA 571
+ E ++L + + ++ + + L ++ +L K+ + EL+E +
Sbjct: 1228 GL---ETDNKELACEVKVLQQV-KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKAS 1283
Query: 572 KKDQELEQ-QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVN 630
K EL+ + + IK ++ ++ + + ++EL LQ++ ++ + +
Sbjct: 1284 KLQNELDNVSTLLEEAEKKGIKFAKDAASL--ESQLQDTQEL--LQEETRQKLNLSSRI- 1338
Query: 631 KQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
+Q+ + + +QE E +++ LEK VLAL
Sbjct: 1339 RQLEEEKNSLQE---QQEEEEEARKNLEKQVLAL 1369
Score = 67.3 bits (157), Expect = 2e-10
Identities = 83/413 (20%), Positives = 180/413 (43%), Gaps = 27/413 (6%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQ---LREAEASITSLTGTVKMLEDQ 317
EL + L +KEK T E +L + + ++ ++ L E + T L + + +
Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRAR 912
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
K+ +LE L ++ E L ++ +QA + + ++Q+++ + Q
Sbjct: 913 LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL--Q 970
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
LE+ + K E+ + + K E +L + R I E +++ E E+ N
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR--IAECSSQLAEEEEKAKNLAKI 1028
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
++ + ++L+ + T E+ KR+ + E +Q ++A +E+ ++
Sbjct: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET-TDLQDQIAELQAQIDELKLQLAK 1087
Query: 498 QTRELIKNIKLNEQKVIQYE---QYVRDLQAHNRTIANCQESPNGI------SYQDLQQE 548
+ EL + + + + + VR+LQA + ES +DL +E
Sbjct: 1088 KEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEE 1147
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQE-------LEQQDKNSRGQARVIKIREELINVL 601
+ LK +L D + E+ K++QE LE++ KN Q + ++ R
Sbjct: 1148 LEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEE 1207
Query: 602 KNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+++ EQ++ A +LE + ++ NK++A + +Q++ A E+K++++
Sbjct: 1208 LSEQLEQAKRFKA---NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1257
Score = 58.8 bits (136), Expect = 6e-08
Identities = 108/546 (19%), Positives = 240/546 (43%), Gaps = 56/546 (10%)
Query: 154 KTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRT 213
+T +N + E + +Q E A + L+ Q + + D K+ + T
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1386
Query: 214 LIAVGEA---LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
+ ++ EA L+++ L Q +E + + D++ + ++ + + L+++ +LD +R
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQ--QELDDLTVDLDHQRQVAS 1444
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI----TSLTGTVKMLEDQSRQKEVQLE 326
+++K + L + ++ A+ ++ AEA T + LE+ KE + E
Sbjct: 1445 NLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE-EFE 1503
Query: 327 ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK 386
+ ++LR ++ + + + L+ +QQ+E++ Q +++LE++L+ T+
Sbjct: 1504 RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ----LEELEDELQATE 1559
Query: 387 RA---LQEQCEITKREIE--LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT--- 438
A L+ + K + E L+ R E + R I++++ ELE + L
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1619
Query: 439 -EREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
+ EIDL +L+A E DEV R+ +++ K Q++L +++EI + +
Sbjct: 1620 KKMEIDL-KDLEAQIEAANKARDEVIKQLRKLQAQMK-DYQRELEEARASRDEIFAQSKE 1677
Query: 498 QTREL----IKNIKLNEQ-----KVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE 548
++L + ++L E+ + ++ + RD A T + +S + L+
Sbjct: 1678 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEAR 1737
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELE-------------QQDKNSRGQA----RVI 591
I L+ +L + E L++ K +++ Q+ N+R Q + +
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 592 KIR-EELINVLKNKETEQSRELAA----LQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
K + +EL +K+K L A L++ LE + NK + +++E+F
Sbjct: 1798 KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQ 1857
Query: 647 LENKQQ 652
+E++++
Sbjct: 1858 VEDERR 1863
Score = 51.2 bits (117), Expect = 1e-05
Identities = 41/191 (21%), Positives = 89/191 (46%), Gaps = 7/191 (3%)
Query: 242 IRELRSESENTKALEEMRHELDEERTAKL-AIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
I +L E E ++ E+ ++ + T ++ + +L S +++ N ++++Q +E
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDSLQAEV 357
+A + L G VK + + LEA+ +L E L+ ++L+++ + E+
Sbjct: 1798 KAKLQELEGAVK---SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEI 1854
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ + Q+K +++ +KQ KR L+E E R + + + EL D+ A
Sbjct: 1855 FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1914
Query: 418 EELQAKIIELE 428
E L ++ L+
Sbjct: 1915 EGLSREVSTLK 1925
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/210 (23%), Positives = 103/210 (49%), Gaps = 21/210 (10%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
+E K + +E + + E EL S + E+ R EL +E T + K L +
Sbjct: 1676 KESEKKLKSLEAEILQLQE--ELASSERARRHAEQERDELADEITNSASGKSALL---DE 1730
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTG 339
R+ R+A+++++L E ++++ ++L D+ R+ +Q++ +L R + +
Sbjct: 1731 KRRLEARIAQLEEELEEEQSNM-------ELLNDRFRKTTLQVDTLNAELAAERSAAQKS 1783
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
+ QL +Q L+A++ E + ++ K T+ A I QLEE L+Q + ++
Sbjct: 1784 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL 1843
Query: 396 TKR-EIELKERTETELQDSRNAIEELQAKI 424
+R E +LKE +++D R ++ + ++
Sbjct: 1844 VRRTEKKLKE-IFMQVEDERRHADQYKEQM 1872
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
protein protein.
Length = 2442
Score = 81.4 bits (192), Expect = 1e-14
Identities = 104/459 (22%), Positives = 214/459 (46%), Gaps = 53/459 (11%)
Query: 219 EALVREVAKLRQDV----ETRNVMIDEIRELRSESENTKA--------LEEMRHELDEER 266
EA+ + KL QD+ +TR+V+ D++++L +T+A L++++ +L + +
Sbjct: 1239 EAVASALLKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQ 1298
Query: 267 TAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKML----EDQSRQKE 322
K + K + ES+L + +A + +LR AE G ++L E+ + Q E
Sbjct: 1299 EEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVE 1358
Query: 323 ----VQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKS 373
+EARA+ L E L+T + +L + + E + Q+ +L V
Sbjct: 1359 HLQAAVVEARAQASAAGILEEDLRTAR-SALKLKNEEVESERERAQALQEQGELKVAQGK 1417
Query: 374 AIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN 433
A+Q+ L QT +E+ E + +I+ E+ + E+Q + A+E L ++L+K
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEK-QREMQ--KAALELLS---LDLKKRNQE 1471
Query: 434 PDLPTE--REID--------LWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
DL E +E++ L +Q ++ L V +++ ++++E++ + Q L
Sbjct: 1472 VDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIREPEKDRETQRNVLEHQLL-- 1529
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC--QESPNGIS 541
EL K+++I + Q ++L K + E ++ E+ ++ + I Q ++
Sbjct: 1530 ELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVA 1589
Query: 542 YQDLQQEIMDLKMKL---LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI-KIREEL 597
L ++ + +L +H E S +LA++ QE +Q+ K+ R Q + + +E L
Sbjct: 1590 LTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHL 1649
Query: 598 INVLKNKETE---QSRELAALQQDLEHRMRIVDEVNKQI 633
L+ ++ E Q + L+ + +I++E +QI
Sbjct: 1650 TQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQI 1688
Score = 73.3 bits (172), Expect = 3e-12
Identities = 86/422 (20%), Positives = 190/422 (45%), Gaps = 37/422 (8%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
R+ V AL R + + + N + E+ +LR+ + AL E LD K+
Sbjct: 560 RQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEAL-ALD-----KV 613
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
+ ++L E + + +R+ ++ + + + + +K LEA+ +
Sbjct: 614 GLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAE----AEKRREALWEKNTHLEAQLQ 669
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K E+ + + ++++ +Q ++ E + Q E T Q + Q+ + + RA+Q
Sbjct: 670 KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQ 729
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQA-----KIIE--LEKSKPNPDLPTEREID 443
E+ + + + L+ R + +D ++ +LQ +++E L +++ + E +
Sbjct: 730 EKEALVREKAALEVRLQAVERDRQDLAAQLQGLSSAKELLESSLFEAQQQNSVIDEPQGQ 789
Query: 444 LWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK-LAAELLNKEEIIGKMQIQTREL 502
L ++Q + V + EV K E ++E Q++ AA L + E GK ++ ++
Sbjct: 790 LEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKA 849
Query: 503 IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
++N+ + E++ ++ H + +A ES L++E M+L+M+L + +
Sbjct: 850 AHEKEVNQLR----EKWEKERSWHQQELAKALES--------LEREKMELEMRLKE---Q 894
Query: 563 NEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLKNKETE---QSRELAALQQD 618
E+ I A++++E Q + + Q K R L+ L + E S++L L+QD
Sbjct: 895 QTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQD 954
Query: 619 LE 620
++
Sbjct: 955 MK 956
Score = 67.7 bits (158), Expect = 1e-10
Identities = 115/494 (23%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-----------DVET 234
L++ + Q + +V + A ER + V +RE K R+ ++E
Sbjct: 1474 LQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIREPEKDRETQRNVLEHQLLELEK 1533
Query: 235 RNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT-ESQLRQTRNRVAK 292
++ MI+ R +++ + LE + EL EE K+ ++KL E Q R +
Sbjct: 1534 KDQMIESQRGQVQDLKKQLVTLECLALEL-EENHHKMECQQKLIKELEGQRETQRVALTH 1592
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTGEVTTSQLIQQ 349
+ L E + + + + LE S +L+ R +++ RE ++ + L Q
Sbjct: 1593 LTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQD 1652
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ-CEITKREIELKERTET 408
+ E++ K++I+ L Q + LEEDL+Q K +L+E+ E+T + ++ER E
Sbjct: 1653 LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEE 1712
Query: 409 ELQDSRNAIEELQ-AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
S+ L+ K+I +K K E + + ELQ K+ L E ++ R
Sbjct: 1713 GKGPSKAQRGSLEHMKLILRDKEK-----EVECQQEHIHELQELKDQL---EQQLQGLHR 1764
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV-IQYEQYVRDLQAH 526
K+G L L +E+ I +Q Q +E + +L EQ + Q ++ R L
Sbjct: 1765 ------KVGETSLL---LSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR 1815
Query: 527 NRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHR--NEELSEILAKKDQELEQQDKN 583
++ + A QE ++ +E D L+ H E E+ K+Q + ++
Sbjct: 1816 DQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQ-ARRLEEE 1874
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
+ R ++ EE++ L+ + EQ + L ALQQ + E + A D +
Sbjct: 1875 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQ---AQEHEVETRALQDSWLQA 1931
Query: 644 FATLENKQQQIHRL 657
A L+ + Q++ L
Sbjct: 1932 QAVLKERDQELEAL 1945
Score = 63.3 bits (147), Expect = 3e-09
Identities = 107/478 (22%), Positives = 204/478 (42%), Gaps = 50/478 (10%)
Query: 219 EALVREVAKLRQDVETRN--VMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEK- 275
E L R+ L QD+E R+ +M+ + R E + T+ + + +L++ KL+++E+
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQ---IKLSLRERG 1696
Query: 276 -LTTTESQLRQTRNRVAK------------MDKQLREAEASITSLTGTVKMLEDQSRQKE 322
TT+ QL Q R K M LR+ E + + L++ Q E
Sbjct: 1697 RELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLE 1756
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDL 382
QL+ RK+ E TS L+ QR+ E++ +QQ+++ Q + Q L+ L
Sbjct: 1757 QQLQGLHRKVGE--------TSLLLSQREQ---EIVVLQQQLQEAREQGELKEQSLQSQL 1805
Query: 383 KQTKRAL---QEQCEITKREIELKERTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPT 438
+ +RAL ++ E ++E + + E +++ +A++ L+ + L++
Sbjct: 1806 DEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHK 1865
Query: 439 EREIDLWAELQATKETLRVTEDEVTTCKREKESENK--IGIQQKLAAELLNKEEIIGKMQ 496
E+ L EL ++ E+ + + E + K + +QQ+ A + E +Q
Sbjct: 1866 EQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQ 1925
Query: 497 ---IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLK 553
+Q + ++K + + Q R + R A + G ++ LQ + +
Sbjct: 1926 DSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGK----E 1981
Query: 554 MKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI--NVLKNKETEQSRE 611
LL+ + L A L+ +SR ++I+E I L+ +E Q +
Sbjct: 1982 QHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQ 2041
Query: 612 LAALQQD--LEHRMRIVDEVNKQIAAKADE--IQE-LFATLENKQQQIHRLEKIVLAL 664
A Q+D L H+ + K +A + E IQE LE ++++I L + V L
Sbjct: 2042 QALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGLEREEEEIRGLHQSVREL 2099
Score = 61.3 bits (142), Expect = 1e-08
Identities = 75/410 (18%), Positives = 178/410 (43%), Gaps = 14/410 (3%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
+E+ L+Q+ + + ++E + ALE+ L E KE+ E +
Sbjct: 1817 QELEALQQEQQQAQGQEERVKEKADALQG--ALEQAHMTLKERHGELQDHKEQARRLEEE 1874
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVT 342
L RV +++ L + A + L+ Q ++ + E R L++S +
Sbjct: 1875 LAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAV 1934
Query: 343 TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL 402
+ Q+ ++L+AE + Q E ++ + L+E L + ALQ + + + EL
Sbjct: 1935 LKERDQELEALRAESQSSRHQEEAA----RARAEALQEALGKAHAALQGKEQHLLEQAEL 1990
Query: 403 KERTETELQDSRNAIEELQAKIIELEKS-KPNPDLPTEREIDLWAELQATKETLRVTEDE 461
E + +++ QA +LE++ + ++++ ++Q ++ L DE
Sbjct: 1991 SRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQAL-AQRDE 2049
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIG--KMQIQTRELIKNIKLNEQKVIQYEQY 519
++E+E + + Q++ ++ +++ +G + + + R L ++++ + + Q EQ
Sbjct: 2050 ELRHQQEREQLLEKSLAQRVQENMIQEKQNLGLEREEEEIRGLHQSVRELQLTLAQKEQE 2109
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
+ +L+ + N + P+ S++ E LK+ L+ + E A + E +
Sbjct: 2110 ILELR-ETQQRNNLEALPH--SHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEARE 2166
Query: 580 QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEV 629
+ + Q + + + +V +E + + L++D E + R+ DE+
Sbjct: 2167 IEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSE-QQRLQDEL 2215
Score = 54.4 bits (125), Expect = 1e-06
Identities = 104/509 (20%), Positives = 222/509 (43%), Gaps = 43/509 (8%)
Query: 168 ILEHLSRYNDQGFELCGALRE----LKTQAEDAVNTVTDLSKRACHERRTLIAV----GE 219
+L + N+ ++ ALRE L+T + + LS+ A E+ +L V +
Sbjct: 291 LLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQ 350
Query: 220 ALVREVAKLRQDVETRNVMIDE--IRELRSESENTKALEEMRHELDEERTAKLAIKEKLT 277
+V E + Q N + E I + KAL +R L R A ++++L
Sbjct: 351 VMVEEGDNIAQGSGLENSLELESSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLA 410
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
+ + + + + +++ + + LTG L Q+ + ++++ +++ RE L+
Sbjct: 411 GCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE-RELLQ 469
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
+L QQ + L+ E ++ +L +Q SA Q EE ++ A++E+ + +
Sbjct: 470 KAR---EELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQE 526
Query: 398 REIELKERTE---TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET 454
+ L+ + +EL R A+E + + L + + R AEL +++ T
Sbjct: 527 MLMGLEAKQSESLSELITLREALESIHLEGELLRQEQTEVTAALARAEQSIAELSSSENT 586
Query: 455 LR--VTEDEVTTCKREKESE----NKIGIQQKLAAELLNKEEIIGKMQI--QTRELIKNI 506
L+ V + K +E +K+G+ Q+L + + +M+ Q R ++ +
Sbjct: 587 LKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQ-V 645
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS--YQDLQQEIMDLKMKLLDVVHRNE 564
L E + + + ++ + + +E+ + +D+Q+E +++ KL + H+ E
Sbjct: 646 DLAEAEKRREALWEKNTHLEAQ-LQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQE 704
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
+ L + QE ++Q++ AR ++ +E L+ RE AAL+ L+ R
Sbjct: 705 AATTQLEQLHQEAKRQEEVL---ARAVQEKEALV-----------REKAALEVRLQAVER 750
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQ 653
++ Q+ + + L ++L QQQ
Sbjct: 751 DRQDLAAQLQGLSSAKELLESSLFEAQQQ 779
Score = 54.4 bits (125), Expect = 1e-06
Identities = 116/554 (20%), Positives = 241/554 (43%), Gaps = 51/554 (9%)
Query: 118 QEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYND 177
+E A+ +RD +A+ E++ LL + M ++ ++ K+ L V QD + + + +
Sbjct: 981 KEAARQHRDDLAALQEESS-SLLQDKMDLQKQVEDLKSQL-VAQDDSQRLVEQEVQEKLR 1038
Query: 178 QGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR--EVAKLRQDVETR 235
+ E +EL + E A T++ + K E+R L+ +R E++ LRQD++
Sbjct: 1039 ETQEYNRIQKEL--EREKASLTLSLMEK----EQRLLVLQEADSIRQQELSALRQDMQEA 1092
Query: 236 NVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQT----RNRV 290
E +EL ++ E + ++E + + L E TE QLR + +
Sbjct: 1093 Q---GEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKA 1149
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
A++ +LR E+ + +L + Q + QL + L+++L + + +L
Sbjct: 1150 AQLHLRLRSTESQLEALAA--EQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGG 1207
Query: 351 DSLQAEV-LECKQQ-----------IEKLTVQH-KSAIQQLEEDL---KQTKRALQEQCE 394
DS + LE Q + L+ + SA+ +L +DL +QT+ L++Q
Sbjct: 1208 DSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALLKLHQDLWKTQQTRDVLRDQ-- 1265
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET 454
+ K E L + TE E +++LQ ++ + ++ K + ++ L +EL ET
Sbjct: 1266 VQKLEERLTD-TEAEKSQVHTELQDLQRQLSQNQEEKSKWE---GKQNSLESELMELHET 1321
Query: 455 LRVTEDEVTTCKREK-ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ + + + ++ E++ + + Q L + E + ++ R + E+ +
Sbjct: 1322 MASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDL 1381
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQD----LQQEIMDLKMKLL-DVVHRNEELSE 568
L+ N + + +E + Q Q + + + LL + EE E
Sbjct: 1382 RTARSA---LKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVE 1438
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L + QELE+Q + + ++ + + N + + EQ +EL + LEH V E
Sbjct: 1439 TLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQE 1498
Query: 629 VNKQIAAKADEIQE 642
+++ + ++I+E
Sbjct: 1499 REQKLTVQREQIRE 1512
Score = 53.2 bits (122), Expect = 3e-06
Identities = 104/535 (19%), Positives = 221/535 (41%), Gaps = 38/535 (7%)
Query: 133 PENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQ 192
P L LL +T +E L Q ++ GD+ + + D+ EL L + + Q
Sbjct: 243 PAQLLLLLAKTQELEKEAHERSQELI--QLKSQGDLEK--AELQDRVTELSALLTQSQKQ 298
Query: 193 AEDAVNTVTDLSKRA--CHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESE 250
ED + L + T + EA + A+ + + + V+ D + + E +
Sbjct: 299 NEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQ-EEKLSLQQVIKDITQVMVEEGD 357
Query: 251 NTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGT 310
N + + L+ E + + + + L R+ + + + +++ +
Sbjct: 358 NIAQGSGLENSLELE--SSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEA 415
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
V +L+ Q Q E + +A ++L++ TGE RD+L + ++ + +++ L+ +
Sbjct: 416 VNLLQQQHDQWEEEGKALRQRLQKL--TGE---------RDTLAGQTVDLQGEVDSLS-K 463
Query: 371 HKSAIQQLEEDLKQTKRAL-QEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEK 429
+ +Q+ E+L+Q L QE + + +EL+ + ++ EEL + E E+
Sbjct: 464 ERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERER 523
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREK-ESENKIGIQQKLAAELLNK 488
+ ++ + +EL +E L E ++E+ E + ++ AEL +
Sbjct: 524 LQEMLMGLEAKQSESLSELITLREALESIHLEGELLRQEQTEVTAALARAEQSIAELSSS 583
Query: 489 EEIIGKMQIQTR-ELIKNIKLNEQKVIQ---YEQYVRDLQAHNRTIANCQESPNGISYQD 544
E + R +K LNE + Q + L+ N+++ + E+
Sbjct: 584 ENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEA-------- 635
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKN 603
+Q L++ L + R E L E + +L++ ++ + QA + I+EE + K
Sbjct: 636 AEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKK 695
Query: 604 -KETEQSRELAALQ-QDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
E+ +E A Q + L + +EV + + + + A LE + Q + R
Sbjct: 696 LSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVER 750
Score = 53.2 bits (122), Expect = 3e-06
Identities = 101/500 (20%), Positives = 209/500 (41%), Gaps = 48/500 (9%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVE---TRNVMIDEIR-- 243
L+TQ ++A + + +++ + L +L+++ L++ VE ++ V D+ +
Sbjct: 969 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL 1028
Query: 244 ---ELRSESENTKALEEMRHELDEER---TAKLAIKEKLTTTESQLRQTRNR-VAKMDKQ 296
E++ + T+ ++ EL+ E+ T L KE+ + R + ++ + +
Sbjct: 1029 VEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQD 1088
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE 356
++EA+ L+ +++L + ++KE A+ +L E L+ +T QL R SL A+
Sbjct: 1089 MQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQL---RASLWAQ 1145
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
+ Q L ++ +S QLE + + Q Q + + + LQ + +
Sbjct: 1146 EAKAAQ----LHLRLRSTESQLEALAAEQQPGNQAQAQAQLASL------YSALQQALGS 1195
Query: 417 IEELQAKIIELEKSKPN-----PDLPTEREI----DLWAELQATKETLRVTEDEVTTCKR 467
+ E + ++ S P+ PD R + L L A + + K
Sbjct: 1196 VCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALLKLHQDLWKT 1255
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
++ + QKL L + E ++ + ++L + + N+++ ++E L++
Sbjct: 1256 QQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESEL 1315
Query: 528 RTIANCQES-PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+ S + + +LQ+ + +LL N L + + L+ +R
Sbjct: 1316 MELHETMASLQSRLRRAELQRMEAQGERELLQAAKEN------LTAQVEHLQAAVVEARA 1369
Query: 587 QARVIKIREELINV------LKNKETEQSRELA-ALQQDLEHRMRIVDEVNKQIAAKADE 639
QA I EE + LKN+E E RE A ALQ+ E ++ + + +A
Sbjct: 1370 QASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQT 1429
Query: 640 IQELFATLENKQQQIHRLEK 659
+ E +E + QI LEK
Sbjct: 1430 LAEREEEVETLRGQIQELEK 1449
Score = 46.8 bits (106), Expect = 3e-04
Identities = 100/489 (20%), Positives = 196/489 (40%), Gaps = 44/489 (8%)
Query: 177 DQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN 236
DQ E A + E+A + + A + + E + E A+L + +E
Sbjct: 1939 DQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEAST 1998
Query: 237 VMIDEIRELRSESENTKALEE-MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
+ L + +++ LEE +R + E + L +E + + L Q + +
Sbjct: 1999 ATLQA--SLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQE 2056
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ----LIQQRD 351
+ + E S+ + E Q+ E + E R L +S++ ++T +Q +++ R+
Sbjct: 2057 REQLLEKSLAQRVQENMIQEKQNLGLERE-EEEIRGLHQSVRELQLTLAQKEQEILELRE 2115
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQ--QLEEDLKQTKRALQEQCEITK-REIELKERTET 408
+ Q LE K + + +++ LE L++ LQ T+ REIE +E+ +
Sbjct: 2116 TQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQD 2175
Query: 409 ---ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE--DEVT 463
L ++ ++ LQ + L+ S D +R D EL+ T+ L
Sbjct: 2176 LALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQD---ELELTRRALEKERLHSPGA 2232
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
T E S + G+Q + + + G + R+ ++++ +Q V + E L
Sbjct: 2233 TSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHL---QQAVARLEIDRSRL 2289
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNE-ELSEILAKKDQELEQQ-D 581
Q HN + + E +++E LK + + E+S+ A + + +
Sbjct: 2290 QRHNVQLRSTLEQ--------VERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQ 2341
Query: 582 KNSRG------QARVIKIREELINVLKNKE------TEQSRELAALQQDLEHRMRIVDEV 629
KNS Q V+ ++ +L K K+ + SRELA L L H + V +
Sbjct: 2342 KNSNAKCVAELQKEVVLLQAQLTLERKQKQDYITRSAQTSRELAGLHHSLSHSLLAVAQA 2401
Query: 630 NKQIAAKAD 638
+ +A+
Sbjct: 2402 PEATVLEAE 2410
Score = 40.3 bits (90), Expect = 0.023
Identities = 66/344 (19%), Positives = 147/344 (42%), Gaps = 30/344 (8%)
Query: 212 RTLIAVGEALVREVAKLRQDVETRNVMIDEIREL------RSESENTKALEEMR--HELD 263
+T+ E + EV L+ +++T ++ R+ ++E E ALE+ + HE +
Sbjct: 795 QTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKE 854
Query: 264 EERTAKLAIKEKLTTTES---QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
+ + KE+ + L +++ +L+E + + ++ + Q+
Sbjct: 855 VNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAES 914
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI----- 375
Q++ K R SL + T + + S Q E L +++KL Q + I
Sbjct: 915 ALCQMQLETEKERVSLLETLLQTQKELADA-SQQLERLRQDMKVQKLKEQETTGILQTQL 973
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPD 435
Q+ + +LK+ R Q + ++ + E + ++ D + +E+L+++++ + S+ +
Sbjct: 974 QEAQRELKEAAR--QHRDDLAALQEESSSLLQDKM-DLQKQVEDLKSQLVAQDDSQRLVE 1030
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKE------SENKIGIQQKLAAELLNKE 489
+ ++ E ++ L + +T EKE E QQ+L+A + +
Sbjct: 1031 QEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQ 1090
Query: 490 EIIG---KMQIQTRELIKNIKLNEQKVIQYE-QYVRDLQAHNRT 529
E G ++ Q L + +K E + E Q + +L+A + T
Sbjct: 1091 EAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHIT 1134
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 81.4 bits (192), Expect = 1e-14
Identities = 116/576 (20%), Positives = 251/576 (43%), Gaps = 35/576 (6%)
Query: 103 LPQELILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQD 162
+ +E++L + + +L D IA E + +L +E +N+ K + Q+
Sbjct: 1025 MEEEILLLEDQNSKFIKEKKLMEDRIA----ECSSQLAEEEEKAKNLAK-----IRNKQE 1075
Query: 163 QTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV 222
D+ E L + EL A R+L + D + + +L + + L E L
Sbjct: 1076 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1135
Query: 223 REVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
+A+ + +N + +REL+++ +E + E + ++ K + E+L ++
Sbjct: 1136 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT 1195
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEV 341
+L T + A + + E + L K LE++++ E Q++ +R+ T
Sbjct: 1196 ELEDTLDTTAAQQELRTKREQEVAELK---KALEEETKNHEAQIQ----DMRQRHATALE 1248
Query: 342 TTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
S+ ++Q +A + + KQ +E K +QQ++ + + ++ L Q +
Sbjct: 1249 ELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA 1308
Query: 399 EIELKERTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +R EL + + ++ EL LE+++ + L ++LQ T+E L+
Sbjct: 1309 KVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE 1368
Query: 458 -TEDEVTTCKREK---ESENKIGIQQKLAAELL-NKEEIIGKMQIQTRELIKNIKLNEQK 512
T ++ R + E +N + QQ+ E N E+ + +Q Q + K + +
Sbjct: 1369 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1428
Query: 513 VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV---VHRNEELSEI 569
+ E+ + L ++ E ++Y L++ L+ +L D+ + +++
Sbjct: 1429 IESLEEAKKKLLKDAEALSQRLEE-KALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASN 1487
Query: 570 LAKKDQELEQQDKNSRG-QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK ++ +Q + AR + R+ + KET+ AL++ LE + +
Sbjct: 1488 LEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF-ER 1546
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
NKQ+ A ++++L ++ ++ + +H LEK AL
Sbjct: 1547 QNKQLRA---DMEDLMSSKDDVGKNVHELEKSKRAL 1579
Score = 70.5 bits (165), Expect = 2e-11
Identities = 105/518 (20%), Positives = 218/518 (42%), Gaps = 48/518 (9%)
Query: 172 LSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQD 231
L +G + L++Q +D + + +++ + + + E + ++
Sbjct: 1338 LEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEE 1397
Query: 232 VETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
E R + ++ L+S+ +TK +++ ++ AK + + +L +
Sbjct: 1398 EEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAY 1457
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
K++K + + LT + D RQ LE + +K + L + +++ ++R
Sbjct: 1458 DKLEKTKNRLQQELDDLTVDL----DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEER 1513
Query: 351 DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITK-------REIE 401
D +AE E + + L + A++ EE +Q K RA E +K E+E
Sbjct: 1514 DRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELE 1573
Query: 402 LKERT-ETELQDSRNAIEELQAKIIELEKSKPNPD-----LPTEREIDLWAELQATKETL 455
+R E ++++ R +EEL+ ++ E +K + + + E DL + +E
Sbjct: 1574 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKK 1633
Query: 456 RVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
R+ +V + E E E K + ++K+ +L + E I E+IK ++ +
Sbjct: 1634 RLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQ 1693
Query: 511 QKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQEIMDLKMKLLD--------VVH 561
++ Y++ + + +A + A +ES + + L+ EI+ L+ +L
Sbjct: 1694 AQMKDYQRELEEARASRDEIFAQSKESEKKL--KSLEAEILQLQEELASSERARRHAEQE 1751
Query: 562 RNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEH 621
R+E EI + D+ R +AR+ ++ EEL E EQS + L
Sbjct: 1752 RDELADEITNSASGKSALLDEKRRLEARIAQLEEEL-------EEEQS-NMELLNDRFRK 1803
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
VD +N ++AA+ Q+ +N +QQ+ R K
Sbjct: 1804 TTLQVDTLNAELAAERSAAQK----SDNARQQLERQNK 1837
Score = 67.7 bits (158), Expect = 1e-10
Identities = 100/454 (22%), Positives = 199/454 (43%), Gaps = 31/454 (6%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L E K++ ++ +DE R + + K E + + EE L +
Sbjct: 981 QILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFI 1040
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL---EARARKLRES 335
E +L + +R+A+ QL E E +L E E +L E ++L ++
Sbjct: 1041 KEKKLME--DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1098
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
+ + T+ L Q LQA++ E K Q+ K + + A+ + +++ AL+ E+
Sbjct: 1099 KRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVREL 1158
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ EL+E E+E + SRN E+ + + E ++ L TE E L + A ++ L
Sbjct: 1159 QAQIAELQEDFESE-KASRNKAEKQKRDLSEELEA-----LKTELEDTL--DTTAAQQEL 1210
Query: 456 RV-TEDEVTTCKREKESENK---IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQ 511
R E EV K+ E E K IQ EE+ +++ Q + N++ N+Q
Sbjct: 1211 RTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE-QAKRFKANLEKNKQ 1269
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILA 571
+ E ++L + + ++ + + L ++ +L K+ + EL+E +
Sbjct: 1270 GL---ETDNKELACEVKVLQQV-KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKAS 1325
Query: 572 KKDQELEQ-QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVN 630
K EL+ + + IK ++ ++ + + ++EL LQ++ ++ + +
Sbjct: 1326 KLQNELDNVSTLLEEAEKKGIKFAKDAASL--ESQLQDTQEL--LQEETRQKLNLSSRI- 1380
Query: 631 KQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
+Q+ + + +QE E +++ LEK VLAL
Sbjct: 1381 RQLEEEKNSLQE---QQEEEEEARKNLEKQVLAL 1411
Score = 67.3 bits (157), Expect = 2e-10
Identities = 83/413 (20%), Positives = 180/413 (43%), Gaps = 27/413 (6%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQ---LREAEASITSLTGTVKMLEDQ 317
EL + L +KEK T E +L + + ++ ++ L E + T L + + +
Sbjct: 895 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRAR 954
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
K+ +LE L ++ E L ++ +QA + + ++Q+++ + Q
Sbjct: 955 LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL--Q 1012
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
LE+ + K E+ + + K E +L + R I E +++ E E+ N
Sbjct: 1013 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR--IAECSSQLAEEEEKAKNLAKI 1070
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
++ + ++L+ + T E+ KR+ + E +Q ++A +E+ ++
Sbjct: 1071 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET-TDLQDQIAELQAQIDELKLQLAK 1129
Query: 498 QTRELIKNIKLNEQKVIQYE---QYVRDLQAHNRTIANCQESPNGI------SYQDLQQE 548
+ EL + + + + + VR+LQA + ES +DL +E
Sbjct: 1130 KEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEE 1189
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQE-------LEQQDKNSRGQARVIKIREELINVL 601
+ LK +L D + E+ K++QE LE++ KN Q + ++ R
Sbjct: 1190 LEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEE 1249
Query: 602 KNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+++ EQ++ A +LE + ++ NK++A + +Q++ A E+K++++
Sbjct: 1250 LSEQLEQAKRFKA---NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1299
Score = 58.8 bits (136), Expect = 6e-08
Identities = 108/546 (19%), Positives = 240/546 (43%), Gaps = 56/546 (10%)
Query: 154 KTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRT 213
+T +N + E + +Q E A + L+ Q + + D K+ + T
Sbjct: 1369 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1428
Query: 214 LIAVGEA---LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
+ ++ EA L+++ L Q +E + + D++ + ++ + + L+++ +LD +R
Sbjct: 1429 IESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQ--QELDDLTVDLDHQRQVAS 1486
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI----TSLTGTVKMLEDQSRQKEVQLE 326
+++K + L + ++ A+ ++ AEA T + LE+ KE + E
Sbjct: 1487 NLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE-EFE 1545
Query: 327 ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK 386
+ ++LR ++ + + + L+ +QQ+E++ Q +++LE++L+ T+
Sbjct: 1546 RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ----LEELEDELQATE 1601
Query: 387 RA---LQEQCEITKREIE--LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT--- 438
A L+ + K + E L+ R E + R I++++ ELE + L
Sbjct: 1602 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASK 1661
Query: 439 -EREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
+ EIDL +L+A E DEV R+ +++ K Q++L +++EI + +
Sbjct: 1662 KKMEIDL-KDLEAQIEAANKARDEVIKQLRKLQAQMK-DYQRELEEARASRDEIFAQSKE 1719
Query: 498 QTREL----IKNIKLNEQ-----KVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE 548
++L + ++L E+ + ++ + RD A T + +S + L+
Sbjct: 1720 SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEAR 1779
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELE-------------QQDKNSRGQA----RVI 591
I L+ +L + E L++ K +++ Q+ N+R Q + +
Sbjct: 1780 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1839
Query: 592 KIR-EELINVLKNKETEQSRELAA----LQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
K + +EL +K+K L A L++ LE + NK + +++E+F
Sbjct: 1840 KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQ 1899
Query: 647 LENKQQ 652
+E++++
Sbjct: 1900 VEDERR 1905
Score = 51.2 bits (117), Expect = 1e-05
Identities = 41/191 (21%), Positives = 89/191 (46%), Gaps = 7/191 (3%)
Query: 242 IRELRSESENTKALEEMRHELDEERTAKL-AIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
I +L E E ++ E+ ++ + T ++ + +L S +++ N ++++Q +E
Sbjct: 1780 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1839
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDSLQAEV 357
+A + L G VK + + LEA+ +L E L+ ++L+++ + E+
Sbjct: 1840 KAKLQELEGAVK---SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEI 1896
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ + Q+K +++ +KQ KR L+E E R + + + EL D+ A
Sbjct: 1897 FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1956
Query: 418 EELQAKIIELE 428
E L ++ L+
Sbjct: 1957 EGLSREVSTLK 1967
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/210 (23%), Positives = 103/210 (49%), Gaps = 21/210 (10%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
+E K + +E + + E EL S + E+ R EL +E T + K L +
Sbjct: 1718 KESEKKLKSLEAEILQLQE--ELASSERARRHAEQERDELADEITNSASGKSALL---DE 1772
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTG 339
R+ R+A+++++L E ++++ ++L D+ R+ +Q++ +L R + +
Sbjct: 1773 KRRLEARIAQLEEELEEEQSNM-------ELLNDRFRKTTLQVDTLNAELAAERSAAQKS 1825
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
+ QL +Q L+A++ E + ++ K T+ A I QLEE L+Q + ++
Sbjct: 1826 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL 1885
Query: 396 TKR-EIELKERTETELQDSRNAIEELQAKI 424
+R E +LKE +++D R ++ + ++
Sbjct: 1886 VRRTEKKLKE-IFMQVEDERRHADQYKEQM 1914
>AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein.
Length = 1559
Score = 81.0 bits (191), Expect = 1e-14
Identities = 93/451 (20%), Positives = 203/451 (45%), Gaps = 29/451 (6%)
Query: 212 RTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-ALEEMRHELDEERTAKL 270
R + V L ++ +L+ R+++ ++ +E + K +LE+ R E+ +E L
Sbjct: 25 RRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKAL 84
Query: 271 AIKEKLTTTESQLRQTRNR-----VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL 325
+ + +L++ + + V +M + + E + S + E + R+ +
Sbjct: 85 QLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAA 144
Query: 326 EARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQT 385
E RK E +L++ +D + EV E + +EK+ + + IQ+L+E L++
Sbjct: 145 EEFKRKATEC-------QHKLLKAKDQGKPEVGEYAK-LEKINAEQQLKIQELQEKLEKA 196
Query: 386 KRALQEQCEITKREIELKERTETE---LQDSRNAIEELQAKII---ELEKSKPNPDLPTE 439
+A E E+ + + KER E E LQ+ ++ E ++ K++ ELE+ + +
Sbjct: 197 VKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQ 256
Query: 440 R-EIDLWAELQATKETLRVTEDEVTTCKREKES-ENKIGIQQKLAAELLNKEEIIGKMQI 497
E+ L + Q +E ++V ++++ +KE+ EN + Q+ E K +I+ + +
Sbjct: 257 HLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLEN---MMQRHEEEAHEKGKILSEQKA 313
Query: 498 QTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLL 557
+ I+ EQ++++ + L A++ +L+Q+ L+ +
Sbjct: 314 MINAMDSKIRSLEQRIVELSE-ANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAG 372
Query: 558 DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ 617
+ +N +L E L K + + DKN + ++RE + + ++ E R+L LQ
Sbjct: 373 KLEAQNRKLEEQLEKISHQ-DHSDKNRLLELET-RLREVSLE-HEEQKLELKRQLTELQL 429
Query: 618 DLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
L+ R + + AA ++++ LE
Sbjct: 430 SLQERESQLTALQAARAALESQLRQAKTELE 460
Score = 64.5 bits (150), Expect = 1e-09
Identities = 108/580 (18%), Positives = 246/580 (42%), Gaps = 47/580 (8%)
Query: 117 AQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHL-SRY 175
A+E+ + +R+A S+ + L + E IK + +D D + LE++ R+
Sbjct: 241 AEELEEKHREAQVSAQ-HLEVHLKQKEQHYEEKIKVLDNQ--IKKDLADKETLENMMQRH 297
Query: 176 NDQGFELCGALRELKTQAEDAVNTVTDLSKRACH--ERRTLIAVGEALVREVAKLRQDV- 232
++ E L E K + + L +R E L A + K ++++
Sbjct: 298 EEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMI 357
Query: 233 -ETRNVMID-EIRELRSESENTKA---LEEMRHELDEERTAKLAIKEKLTTT----ESQL 283
E R E + + E++N K LE++ H+ ++ L ++ +L E Q
Sbjct: 358 SELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQK 417
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
+ + ++ ++ L+E E+ +T+L LE Q RQ + +LE + E ++
Sbjct: 418 LELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHR 477
Query: 344 SQLIQQRDSLQ---AEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQE------ 391
++ ++ D+L+ + + ++Q+ +LT + Q L + L + A E
Sbjct: 478 DEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRS 537
Query: 392 -----QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
+ EIT+RE++L + +T ++ + L+ ++++LE + + L ER+ + W
Sbjct: 538 EVDHLRREITEREMQLTSQKQT-MEALKTTCTMLEEQVMDLE-ALNDELLEKERQWEAWR 595
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
+ +++ + E +++ Q++ E + + + + L + +
Sbjct: 596 SVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQAL 655
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL 566
K + K + DL+ + + N S Q + +LK +LL+ + ++
Sbjct: 656 KEQKLKAESLSDKLNDLEKKHAML-----EMNARSLQQKLETERELKQRLLEEQAKLQQQ 710
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKI-REELINVLKNKETEQSRELAALQQDLEHRMRI 625
++ L Q + + +A ++K R +L L+N + S E ++ + + ++
Sbjct: 711 MDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKL 770
Query: 626 VDEVNKQI--AAKADEI----QELFATLENKQQQIHRLEK 659
+D + ++ AK ++ EL LE ++ + LE+
Sbjct: 771 IDFLQAKMDQPAKKKKVPLQYNELKLALEKEKARCAELEE 810
>AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 80.6 bits (190), Expect = 2e-14
Identities = 93/439 (21%), Positives = 207/439 (47%), Gaps = 38/439 (8%)
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--REA 300
+ + + E T+ +EE++ +LDEE + ++ E QL + +++ + L R+
Sbjct: 356 KAVAGQGELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKG 415
Query: 301 EASITSL-TGTVKMLEDQSRQKEVQLEARARKLRESLK-------TGEVTTSQLIQQRDS 352
EA ++ +K L DQ LE + +L+ LK EV L++ R+
Sbjct: 416 EAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETREL 475
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL-KERTETELQ 411
L+ EVLE KQ++E+ + + L+ LK+ + ++ E +++ + E+ +Q
Sbjct: 476 LE-EVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQ 534
Query: 412 DSRN---AIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR 467
D+ +E + K+ L + T E W + Q KE LR T+ E+ +
Sbjct: 535 DATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRM 594
Query: 468 EKES-ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
EKE E ++G +K+ E+L +E + + + + + +++ ++++++ ++ +++LQA
Sbjct: 595 EKEEMEEELG--EKI--EVLQRE--LEQARASAGD-TRQVEVLKKELLRTQEELKELQAE 647
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKL---LDVVHRNEELSEILAKKDQELEQQDKN 583
++ QE ++L++++ L+++ ++ +N +L + L + Q+ E+ K
Sbjct: 648 RQS----QEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKA 703
Query: 584 ---SRGQARVIKIREELINVLKNKETEQS----RELAALQQDLEHRMRIVDEVNKQIAAK 636
+ +A V+ R + + E++ R + L+Q L+ +VD A
Sbjct: 704 KMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARL 763
Query: 637 ADEIQELFATLENKQQQIH 655
D++Q L A + ++ ++
Sbjct: 764 RDKLQRLEAEKQQLEEALN 782
Score = 66.1 bits (154), Expect = 4e-10
Identities = 109/476 (22%), Positives = 216/476 (45%), Gaps = 31/476 (6%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV-ETRNVMIDEI 242
G REL+ +E+ + + K R T + + L E ++ +++ E V+ E+
Sbjct: 556 GLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQ-LRMEKEEMEEELGEKIEVLQREL 614
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
+ R+ + +T+ +E ++ EL RT + +KE +SQ R+R +++KQL A
Sbjct: 615 EQARASAGDTRQVEVLKKEL--LRTQE-ELKELQAERQSQEVAGRHRDRELEKQL--AVL 669
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT---GEVTTSQLIQQRDSLQAEVLE 359
+ + G + LE+Q+ Q + L+ + E+ K E + L Q+R +++ + E
Sbjct: 670 RVEADRG--RELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRE 727
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
+++ ++ + I LE+ LK+T+ + + R + +R E E Q A+
Sbjct: 728 TQEENDEF----RRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNA 783
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL-RVTEDEVTTCKREKESENKIGIQ 478
Q + L +K + E A L ++TL R E+E + + + ++ Q
Sbjct: 784 SQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQ 843
Query: 479 QKL---AAELLNKE-EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ 534
++L + LNKE E IG+ Q + ++ +L + K + + V D Q + A+
Sbjct: 844 KRLLDRTVDRLNKELEKIGEDSKQALQQLQ-AQLEDYKE-KARREVADAQRQAKDWASEA 901
Query: 535 ESPNGISYQDLQQEIMDLKMKLL------DVVHRNEEL-SEILAKKDQELEQQDKNSRGQ 587
E +G LQ EI L+ L D ++EL ++ L +QE E + ++ +
Sbjct: 902 EKTSG-GLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDR 960
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
AR +K EE ++ L+ + E+ + L + VD++ ++ + Q+L
Sbjct: 961 ARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDL 1016
Score = 62.1 bits (144), Expect = 6e-09
Identities = 61/249 (24%), Positives = 107/249 (42%), Gaps = 13/249 (5%)
Query: 191 TQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE-IRELRSES 249
++ +D + + + + ER T E L + + L Q+ E + D+ R+L+
Sbjct: 909 SRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLE 968
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTG 309
E LE ELDEE+ + +++ Q+ Q R + + ++ E SL
Sbjct: 969 EKVSRLET---ELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLER 1025
Query: 310 TVKMLEDQSRQKE---------VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
K L+ + E QLE++ + L+E L+ E + L L+ +V E
Sbjct: 1026 QNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKEL 1085
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
QIE QL +K KR + E E +R L+++ + E+++ E+L
Sbjct: 1086 SIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQL 1145
Query: 421 QAKIIELEK 429
QA+I LEK
Sbjct: 1146 QARIKSLEK 1154
Score = 56.8 bits (131), Expect = 2e-07
Identities = 102/473 (21%), Positives = 212/473 (44%), Gaps = 53/473 (11%)
Query: 241 EIRELRSES-ENTKALEEMRHELDEERTA-KLAIKEKLTTTESQLRQTRNRVAKMDKQLR 298
E REL E E + +EE + E TA K A+KE++ + + ++ R + + +QLR
Sbjct: 471 ETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLR 530
Query: 299 EAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA--- 355
S+ T +LE + ++ + R+L E+ + S + ++ L+A
Sbjct: 531 R---SMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQ 587
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE--QCEITKREIELKERTETELQDS 413
E+L+ + + E++ + I+ L+ +L+Q + + + Q E+ K+E+ + ELQ
Sbjct: 588 ELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAE 647
Query: 414 RNAIEEL-QAKIIELEKSKPNPDLPTEREIDLWAE---LQATKETLRVTEDEVTTCKREK 469
R + E + + ELEK + +R +L + LQ T + LR +E + K
Sbjct: 648 RQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVA 707
Query: 470 ESENKIGIQQKLAAELLNKE----------EIIG----------------KMQIQTRELI 503
E+E + Q++ A E +E I+G ++ + R+ +
Sbjct: 708 EAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKL 767
Query: 504 KNIKLNEQKVIQY----EQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKM---- 554
+ ++ +Q++ + ++ L A R + A +E+ G++ +Q+ ++ +
Sbjct: 768 QRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEG 827
Query: 555 KLLDVVHRNE-ELSEILAKKDQELEQQDKNSRGQARVIK-IREELINVLKNKETEQSREL 612
K +V+ R + EL E D+ +++ +K K ++L L++ + + RE+
Sbjct: 828 KQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREV 887
Query: 613 AALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ--QQIHRLEKIVLA 663
A Q+ + ++ + ++ DEIQ L L+ Q + RL+K +LA
Sbjct: 888 ADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLA 940
Score = 43.2 bits (97), Expect = 0.003
Identities = 60/269 (22%), Positives = 121/269 (44%), Gaps = 29/269 (10%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
DEI+ LR +AL+ + E D R K + ++L E ++ N+ D + R+
Sbjct: 913 DEIQRLR------QALQASQAERDTARLDKELLAQRLQGLE---QEAENKKRSQDDRARQ 963
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ L V LE + +++ +E ++ + ++L+Q+R + Q LE
Sbjct: 964 ----LKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQD--LE 1017
Query: 360 C-KQQIEKLTVQHKSAIQQLEEDLKQTKRA--LQEQCEITKREIELKERTETELQDSRNA 416
C K +E+ K+ + E K + L+ Q ++ + ++ +ER +T LQ +
Sbjct: 1018 CDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK 1077
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG 476
+E K+ EL + + ER+ Q + +LRV + + E+E E G
Sbjct: 1078 LER---KVKEL-----SIQIEDERQ---HVNDQKDQLSLRVKALKRQVDEAEEEIERLDG 1126
Query: 477 IQQKLAAELLNKEEIIGKMQIQTRELIKN 505
+++K E+ + E+ ++Q + + L K+
Sbjct: 1127 LRKKAQREVEEQHEVNEQLQARIKSLEKD 1155
>AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 80.6 bits (190), Expect = 2e-14
Identities = 93/439 (21%), Positives = 207/439 (47%), Gaps = 38/439 (8%)
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--REA 300
+ + + E T+ +EE++ +LDEE + ++ E QL + +++ + L R+
Sbjct: 356 KAVAGQGELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKG 415
Query: 301 EASITSL-TGTVKMLEDQSRQKEVQLEARARKLRESLK-------TGEVTTSQLIQQRDS 352
EA ++ +K L DQ LE + +L+ LK EV L++ R+
Sbjct: 416 EAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETREL 475
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL-KERTETELQ 411
L+ EVLE KQ++E+ + + L+ LK+ + ++ E +++ + E+ +Q
Sbjct: 476 LE-EVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQ 534
Query: 412 DSRN---AIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR 467
D+ +E + K+ L + T E W + Q KE LR T+ E+ +
Sbjct: 535 DATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRM 594
Query: 468 EKES-ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
EKE E ++G +K+ E+L +E + + + + + +++ ++++++ ++ +++LQA
Sbjct: 595 EKEEMEEELG--EKI--EVLQRE--LEQARASAGD-TRQVEVLKKELLRTQEELKELQAE 647
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKL---LDVVHRNEELSEILAKKDQELEQQDKN 583
++ QE ++L++++ L+++ ++ +N +L + L + Q+ E+ K
Sbjct: 648 RQS----QEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKA 703
Query: 584 ---SRGQARVIKIREELINVLKNKETEQS----RELAALQQDLEHRMRIVDEVNKQIAAK 636
+ +A V+ R + + E++ R + L+Q L+ +VD A
Sbjct: 704 KMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARL 763
Query: 637 ADEIQELFATLENKQQQIH 655
D++Q L A + ++ ++
Sbjct: 764 RDKLQRLEAEKQQLEEALN 782
Score = 66.1 bits (154), Expect = 4e-10
Identities = 109/476 (22%), Positives = 216/476 (45%), Gaps = 31/476 (6%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV-ETRNVMIDEI 242
G REL+ +E+ + + K R T + + L E ++ +++ E V+ E+
Sbjct: 556 GLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQ-LRMEKEEMEEELGEKIEVLQREL 614
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
+ R+ + +T+ +E ++ EL RT + +KE +SQ R+R +++KQL A
Sbjct: 615 EQARASAGDTRQVEVLKKEL--LRTQE-ELKELQAERQSQEVAGRHRDRELEKQL--AVL 669
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT---GEVTTSQLIQQRDSLQAEVLE 359
+ + G + LE+Q+ Q + L+ + E+ K E + L Q+R +++ + E
Sbjct: 670 RVEADRG--RELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRE 727
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
+++ ++ + I LE+ LK+T+ + + R + +R E E Q A+
Sbjct: 728 TQEENDEF----RRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNA 783
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL-RVTEDEVTTCKREKESENKIGIQ 478
Q + L +K + E A L ++TL R E+E + + + ++ Q
Sbjct: 784 SQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQ 843
Query: 479 QKL---AAELLNKE-EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ 534
++L + LNKE E IG+ Q + ++ +L + K + + V D Q + A+
Sbjct: 844 KRLLDRTVDRLNKELEKIGEDSKQALQQLQ-AQLEDYKE-KARREVADAQRQAKDWASEA 901
Query: 535 ESPNGISYQDLQQEIMDLKMKLL------DVVHRNEEL-SEILAKKDQELEQQDKNSRGQ 587
E +G LQ EI L+ L D ++EL ++ L +QE E + ++ +
Sbjct: 902 EKTSG-GLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDR 960
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
AR +K EE ++ L+ + E+ + L + VD++ ++ + Q+L
Sbjct: 961 ARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDL 1016
Score = 62.1 bits (144), Expect = 6e-09
Identities = 61/249 (24%), Positives = 107/249 (42%), Gaps = 13/249 (5%)
Query: 191 TQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE-IRELRSES 249
++ +D + + + + ER T E L + + L Q+ E + D+ R+L+
Sbjct: 909 SRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLE 968
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTG 309
E LE ELDEE+ + +++ Q+ Q R + + ++ E SL
Sbjct: 969 EKVSRLET---ELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLER 1025
Query: 310 TVKMLEDQSRQKE---------VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
K L+ + E QLE++ + L+E L+ E + L L+ +V E
Sbjct: 1026 QNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKEL 1085
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
QIE QL +K KR + E E +R L+++ + E+++ E+L
Sbjct: 1086 SIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQL 1145
Query: 421 QAKIIELEK 429
QA+I LEK
Sbjct: 1146 QARIKSLEK 1154
Score = 56.8 bits (131), Expect = 2e-07
Identities = 102/473 (21%), Positives = 212/473 (44%), Gaps = 53/473 (11%)
Query: 241 EIRELRSES-ENTKALEEMRHELDEERTA-KLAIKEKLTTTESQLRQTRNRVAKMDKQLR 298
E REL E E + +EE + E TA K A+KE++ + + ++ R + + +QLR
Sbjct: 471 ETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLR 530
Query: 299 EAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA--- 355
S+ T +LE + ++ + R+L E+ + S + ++ L+A
Sbjct: 531 R---SMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQ 587
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE--QCEITKREIELKERTETELQDS 413
E+L+ + + E++ + I+ L+ +L+Q + + + Q E+ K+E+ + ELQ
Sbjct: 588 ELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAE 647
Query: 414 RNAIEEL-QAKIIELEKSKPNPDLPTEREIDLWAE---LQATKETLRVTEDEVTTCKREK 469
R + E + + ELEK + +R +L + LQ T + LR +E + K
Sbjct: 648 RQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVA 707
Query: 470 ESENKIGIQQKLAAELLNKE----------EIIG----------------KMQIQTRELI 503
E+E + Q++ A E +E I+G ++ + R+ +
Sbjct: 708 EAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKL 767
Query: 504 KNIKLNEQKVIQY----EQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKM---- 554
+ ++ +Q++ + ++ L A R + A +E+ G++ +Q+ ++ +
Sbjct: 768 QRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEG 827
Query: 555 KLLDVVHRNE-ELSEILAKKDQELEQQDKNSRGQARVIK-IREELINVLKNKETEQSREL 612
K +V+ R + EL E D+ +++ +K K ++L L++ + + RE+
Sbjct: 828 KQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREV 887
Query: 613 AALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ--QQIHRLEKIVLA 663
A Q+ + ++ + ++ DEIQ L L+ Q + RL+K +LA
Sbjct: 888 ADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLA 940
Score = 43.2 bits (97), Expect = 0.003
Identities = 60/269 (22%), Positives = 121/269 (44%), Gaps = 29/269 (10%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
DEI+ LR +AL+ + E D R K + ++L E ++ N+ D + R+
Sbjct: 913 DEIQRLR------QALQASQAERDTARLDKELLAQRLQGLE---QEAENKKRSQDDRARQ 963
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ L V LE + +++ +E ++ + ++L+Q+R + Q LE
Sbjct: 964 ----LKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQD--LE 1017
Query: 360 C-KQQIEKLTVQHKSAIQQLEEDLKQTKRA--LQEQCEITKREIELKERTETELQDSRNA 416
C K +E+ K+ + E K + L+ Q ++ + ++ +ER +T LQ +
Sbjct: 1018 CDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK 1077
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG 476
+E K+ EL + + ER+ Q + +LRV + + E+E E G
Sbjct: 1078 LER---KVKEL-----SIQIEDERQ---HVNDQKDQLSLRVKALKRQVDEAEEEIERLDG 1126
Query: 477 IQQKLAAELLNKEEIIGKMQIQTRELIKN 505
+++K E+ + E+ ++Q + + L K+
Sbjct: 1127 LRKKAQREVEEQHEVNEQLQARIKSLEKD 1155
>AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein.
Length = 2010
Score = 80.6 bits (190), Expect = 2e-14
Identities = 104/500 (20%), Positives = 224/500 (44%), Gaps = 20/500 (4%)
Query: 154 KTNLTVNQDQTDGDILEHLSRYN-DQGFELCGALRELKTQAEDAVNTVTDLSKRACHERR 212
+T++++ Q++ D + + N E C L + K Q E V +++ +
Sbjct: 951 ETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNA 1010
Query: 213 TLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESEN-TKALEEMRHELDEERTAKLA 271
L A L E +L++D++ + + + + + +EN K L E LDE A+L
Sbjct: 1011 DLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDES-VARLT 1069
Query: 272 IKEKLTTTESQLRQTRNRVAKMDK--QLREAEASITSLTGTVKMLEDQSRQKEVQLEARA 329
KEK E+ + + A+ D+ L +A+ + ++ +Q ++ + E
Sbjct: 1070 -KEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAK 1128
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT--VQHKSAI-QQLEEDLKQTK 386
RKL LK + + + Q + L+ ++ + ++ +L+ V+ + + Q+++ +K+ +
Sbjct: 1129 RKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQ 1188
Query: 387 RALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL-EKSKPNPDLPTEREIDLW 445
+E E + E + R E + ++ +EEL ++ E S + +RE +L
Sbjct: 1189 ARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAEL- 1247
Query: 446 AELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
L+ E + + R K++E + +++ + L + + K + + R + +
Sbjct: 1248 GRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDS-LQRVRQKLEKEKSELRMEVDD 1306
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
+ N + + + + L RT + Q S I ++LQ+++ D + + + E
Sbjct: 1307 LAANVETLTRAKASAEKL---CRTYED-QLSEAKIKVEELQRQLADASTQRGRLQTESGE 1362
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
LS +L +K+ + Q SRG+A + EEL L+ +E++ LA Q L H +
Sbjct: 1363 LSRLLEEKECLISQL---SRGKALAAQSLEELRRQLE-EESKAKSALAHAVQALRHDCDL 1418
Query: 626 VDEVNKQIAAKADEIQELFA 645
+ E +++ A E+Q L +
Sbjct: 1419 LREQHEEEAEAQAELQRLLS 1438
Score = 71.7 bits (168), Expect = 8e-12
Identities = 94/453 (20%), Positives = 200/453 (44%), Gaps = 36/453 (7%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
AL + +L Q VE +++ ++LR ++E K E +L +E A A ++K
Sbjct: 1095 ALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAA-QDK---- 1149
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+Q ++ K D +L + + ++L Q ++K +L+ARA +L E L+
Sbjct: 1150 ----QQLEEKLKKKDSELSQLSLRVED----EQLLGAQMQKKIKELQARAEELEEELEAE 1201
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
+++ +QR E+ E +++E+ + + ++ E +L + +R L+E
Sbjct: 1202 RAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRH 1261
Query: 397 KREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ + R + E + ++ LQ +LEK K E+D A T
Sbjct: 1262 EATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSE----LRMEVDDLAANVETLTRA 1317
Query: 456 RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQ 515
+ + +++ ++ SE KI +++ L +L + G++Q ++ EL + ++ E + Q
Sbjct: 1318 KASAEKLCRTYEDQLSEAKIKVEE-LQRQLADASTQRGRLQTESGELSRLLEEKECLISQ 1376
Query: 516 YEQ----YVRDLQAHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEI 569
+ + L+ R + ++ + +++ Q L+ + L+ + + EL +
Sbjct: 1377 LSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRL 1436
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELIN-----VLKNKETEQSRELA-ALQQDLEHRM 623
L+K + E+ Q S+ +A I+ EEL L+ +E E+ E A A LE
Sbjct: 1437 LSKANAEVAQW--RSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAK 1494
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ ++ + + + A L+ KQ+ + R
Sbjct: 1495 LRLQTESEDVTLELERATSAAAALDKKQRHLER 1527
Score = 62.1 bits (144), Expect = 6e-09
Identities = 78/415 (18%), Positives = 191/415 (46%), Gaps = 39/415 (9%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTG-----TVKMLEDQSR-------- 319
+E+L ++LR R +A + + +E E + S+T +++ +Q
Sbjct: 922 EEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERC 981
Query: 320 ----QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI 375
+ +VQLE + ++L E L+ E + L +R L+ E E K+ I+ L + A
Sbjct: 982 HLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAE 1041
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA---KIIELEKSKP 432
++ + + K +E + + L + + + + A+ +LQA ++ L K+K
Sbjct: 1042 KEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAK- 1100
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEII 492
L E++++ +L+ + E + + KR+ E + K+ Q+ +A +K+++
Sbjct: 1101 ---LRLEQQVE---DLECSLEQEKKLRMDTERAKRKLEGDLKL-TQESVADAAQDKQQLE 1153
Query: 493 GKMQIQTRELIK-NIKLNEQKVI--QYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI 549
K++ + EL + ++++ +++++ Q ++ +++LQA + E+ + ++++
Sbjct: 1154 EKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARAR-VEKQR 1212
Query: 550 MDLKMKLLDVVHRNEELSEILAKKDQELEQQDK---NSRGQARVIKIREE-LINVLKNKE 605
+ +L ++ R EE A + + +++ R + +R E + L+ K+
Sbjct: 1213 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 1272
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
E + EL + ++ R+ ++ K+ + E+ +L A +E + EK+
Sbjct: 1273 AEGAAELG---EQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKL 1324
Score = 57.2 bits (132), Expect = 2e-07
Identities = 102/448 (22%), Positives = 197/448 (43%), Gaps = 47/448 (10%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
E AKLR E+ +V ++ R + + K + L+E R + ++ +L + +
Sbjct: 1491 EKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRES 1550
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R + ++ EA ++ +L K L+++ Q+ + ++E E T
Sbjct: 1551 RGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQEL----EKTK 1606
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
L ++ +QA + E + +E + K+ QLE L Q K E+ ++ E
Sbjct: 1607 KALEGEKSEIQAALEEAEGALE--LEETKTLRIQLE--LSQVK------AEVDRKLAEKD 1656
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI--DL-WAELQATKETLRVTED 460
E ++ + A+E LQA ++ E N L ++++ DL ELQ T + TE
Sbjct: 1657 EECANLRRNHQRAVESLQAS-LDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEA 1715
Query: 461 EVTTCKRE---KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
+ T + KE + +Q+LAAEL + + ++ R + +L E + E
Sbjct: 1716 QAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQ-----ALERRASLLAAELEELRA-ALE 1769
Query: 518 QYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL-LDVVHRNEELSEILAKKDQE 576
Q R + + + E N + Q+ +++ K KL D+ + E+ E A++ +E
Sbjct: 1770 QGERSRRLAEQELLEATERLNLLHSQN--TGLLNQKKKLEADLAQLSGEVEE-AAQERRE 1826
Query: 577 LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAK 636
E++ K + A + + EEL KE + S L +++ LE +R ++ A+
Sbjct: 1827 AEEKAKKAITDAAM--MAEEL-----KKEQDTSAHLERMKKTLEQTVR-------ELQAR 1872
Query: 637 ADEIQELFATLENKQQQIHRLEKIVLAL 664
+E ++ A L ++Q+ +LE V L
Sbjct: 1873 LEEAEQ--AALRGGKKQVQKLEAKVREL 1898
Score = 47.6 bits (108), Expect = 1e-04
Identities = 91/459 (19%), Positives = 193/459 (42%), Gaps = 36/459 (7%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+G + +++ +L+ E ++ R R+ E +A E EL EE + +L +E
Sbjct: 1176 LGAQMQKKIKELQARAEELEEELEAERAARARVEKQRA--EAAREL-EELSERL--EEAG 1230
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
+ Q R R A++ + RE E + TV L R+K+ + A +L E +
Sbjct: 1231 GASAGQREGCRKREAELGRLRRELEEAALRHEATVAAL----RRKQAE---GAAELGEQV 1283
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA---IQQLEEDLKQTKRALQE-Q 392
+ + +L +++ L+ EV + +E LT SA + E+ L + K ++E Q
Sbjct: 1284 DSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQ 1343
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE---REIDLWAELQ 449
++ + + R +TE + +EE + I +L + K E R+++ ++ +
Sbjct: 1344 RQLADASTQ-RGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAK 1402
Query: 450 -ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
A ++ + + + E E + + + N E + + + + + +L
Sbjct: 1403 SALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEEL 1462
Query: 509 NEQK---VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
E K ++ ++ ++A N ++ +++ LQ E D+ ++L R
Sbjct: 1463 EEAKKKLALRLQEAEEGVEAANAKCSSLEKAK-----LRLQTESEDVTLEL----ERATS 1513
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
+ L KK + LE+ + R Q ++ RE + + + EL L+ E +
Sbjct: 1514 AAAALDKKQRHLERALEERRRQEEEMQ-RE--LEAAQRESRGLGTELFRLRHGHEEALEA 1570
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
++ + ++ +EI +L + + I LEK AL
Sbjct: 1571 LETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKAL 1609
Score = 43.6 bits (98), Expect = 0.002
Identities = 57/279 (20%), Positives = 115/279 (41%), Gaps = 17/279 (6%)
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
R +E A M+ +L EE+ + + Q + R + + +L E A++
Sbjct: 1710 RQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALE 1769
Query: 306 SLTGTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
+ ++ E + + ++ L ++ L K E +QL + + E E ++
Sbjct: 1770 QGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEE 1829
Query: 363 QIEKLTVQHKSAIQQL--EEDLKQTKRALQEQCEITKREIE--LKERTETELQDSRNAIE 418
+ +K ++L E+D +++ E T RE++ L+E + L+ + ++
Sbjct: 1830 KAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQ 1889
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+L+AK+ ELE +L E++ A K RV E + +E +
Sbjct: 1890 KLEAKVRELE-----AELDAEQKKHAEALKGVRKHERRVKE----LAYQAEEDRKNLARM 1940
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
Q L +L +K + K Q + E N L + + Q+E
Sbjct: 1941 QDLVDKLQSKVKSY-KRQFEEAEQQANTNLAKYRKAQHE 1978
>AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein.
Length = 1208
Score = 80.6 bits (190), Expect = 2e-14
Identities = 93/439 (21%), Positives = 207/439 (47%), Gaps = 38/439 (8%)
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--REA 300
+ + + E T+ +EE++ +LDEE + ++ E QL + +++ + L R+
Sbjct: 361 KAVAGQGELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKG 420
Query: 301 EASITSL-TGTVKMLEDQSRQKEVQLEARARKLRESLK-------TGEVTTSQLIQQRDS 352
EA ++ +K L DQ LE + +L+ LK EV L++ R+
Sbjct: 421 EAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETREL 480
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL-KERTETELQ 411
L+ EVLE KQ++E+ + + L+ LK+ + ++ E +++ + E+ +Q
Sbjct: 481 LE-EVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQ 539
Query: 412 DSRN---AIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR 467
D+ +E + K+ L + T E W + Q KE LR T+ E+ +
Sbjct: 540 DATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRM 599
Query: 468 EKES-ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
EKE E ++G +K+ E+L +E + + + + + +++ ++++++ ++ +++LQA
Sbjct: 600 EKEEMEEELG--EKI--EVLQRE--LEQARASAGD-TRQVEVLKKELLRTQEELKELQAE 652
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKL---LDVVHRNEELSEILAKKDQELEQQDKN 583
++ QE ++L++++ L+++ ++ +N +L + L + Q+ E+ K
Sbjct: 653 RQS----QEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKA 708
Query: 584 ---SRGQARVIKIREELINVLKNKETEQS----RELAALQQDLEHRMRIVDEVNKQIAAK 636
+ +A V+ R + + E++ R + L+Q L+ +VD A
Sbjct: 709 KMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARL 768
Query: 637 ADEIQELFATLENKQQQIH 655
D++Q L A + ++ ++
Sbjct: 769 RDKLQRLEAEKQQLEEALN 787
Score = 66.1 bits (154), Expect = 4e-10
Identities = 109/476 (22%), Positives = 216/476 (45%), Gaps = 31/476 (6%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV-ETRNVMIDEI 242
G REL+ +E+ + + K R T + + L E ++ +++ E V+ E+
Sbjct: 561 GLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQ-LRMEKEEMEEELGEKIEVLQREL 619
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
+ R+ + +T+ +E ++ EL RT + +KE +SQ R+R +++KQL A
Sbjct: 620 EQARASAGDTRQVEVLKKEL--LRTQE-ELKELQAERQSQEVAGRHRDRELEKQL--AVL 674
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT---GEVTTSQLIQQRDSLQAEVLE 359
+ + G + LE+Q+ Q + L+ + E+ K E + L Q+R +++ + E
Sbjct: 675 RVEADRG--RELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRE 732
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
+++ ++ + I LE+ LK+T+ + + R + +R E E Q A+
Sbjct: 733 TQEENDEF----RRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNA 788
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL-RVTEDEVTTCKREKESENKIGIQ 478
Q + L +K + E A L ++TL R E+E + + + ++ Q
Sbjct: 789 SQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQ 848
Query: 479 QKL---AAELLNKE-EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ 534
++L + LNKE E IG+ Q + ++ +L + K + + V D Q + A+
Sbjct: 849 KRLLDRTVDRLNKELEKIGEDSKQALQQLQ-AQLEDYKE-KARREVADAQRQAKDWASEA 906
Query: 535 ESPNGISYQDLQQEIMDLKMKLL------DVVHRNEEL-SEILAKKDQELEQQDKNSRGQ 587
E +G LQ EI L+ L D ++EL ++ L +QE E + ++ +
Sbjct: 907 EKTSG-GLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDR 965
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
AR +K EE ++ L+ + E+ + L + VD++ ++ + Q+L
Sbjct: 966 ARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDL 1021
Score = 62.1 bits (144), Expect = 6e-09
Identities = 61/249 (24%), Positives = 107/249 (42%), Gaps = 13/249 (5%)
Query: 191 TQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE-IRELRSES 249
++ +D + + + + ER T E L + + L Q+ E + D+ R+L+
Sbjct: 914 SRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLE 973
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTG 309
E LE ELDEE+ + +++ Q+ Q R + + ++ E SL
Sbjct: 974 EKVSRLET---ELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLER 1030
Query: 310 TVKMLEDQSRQKE---------VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
K L+ + E QLE++ + L+E L+ E + L L+ +V E
Sbjct: 1031 QNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKEL 1090
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
QIE QL +K KR + E E +R L+++ + E+++ E+L
Sbjct: 1091 SIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQL 1150
Query: 421 QAKIIELEK 429
QA+I LEK
Sbjct: 1151 QARIKSLEK 1159
Score = 56.8 bits (131), Expect = 2e-07
Identities = 102/473 (21%), Positives = 212/473 (44%), Gaps = 53/473 (11%)
Query: 241 EIRELRSES-ENTKALEEMRHELDEERTA-KLAIKEKLTTTESQLRQTRNRVAKMDKQLR 298
E REL E E + +EE + E TA K A+KE++ + + ++ R + + +QLR
Sbjct: 476 ETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLR 535
Query: 299 EAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA--- 355
S+ T +LE + ++ + R+L E+ + S + ++ L+A
Sbjct: 536 R---SMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQ 592
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE--QCEITKREIELKERTETELQDS 413
E+L+ + + E++ + I+ L+ +L+Q + + + Q E+ K+E+ + ELQ
Sbjct: 593 ELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAE 652
Query: 414 RNAIEEL-QAKIIELEKSKPNPDLPTEREIDLWAE---LQATKETLRVTEDEVTTCKREK 469
R + E + + ELEK + +R +L + LQ T + LR +E + K
Sbjct: 653 RQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVA 712
Query: 470 ESENKIGIQQKLAAELLNKE----------EIIG----------------KMQIQTRELI 503
E+E + Q++ A E +E I+G ++ + R+ +
Sbjct: 713 EAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKL 772
Query: 504 KNIKLNEQKVIQY----EQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKM---- 554
+ ++ +Q++ + ++ L A R + A +E+ G++ +Q+ ++ +
Sbjct: 773 QRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEG 832
Query: 555 KLLDVVHRNE-ELSEILAKKDQELEQQDKNSRGQARVIK-IREELINVLKNKETEQSREL 612
K +V+ R + EL E D+ +++ +K K ++L L++ + + RE+
Sbjct: 833 KQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREV 892
Query: 613 AALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ--QQIHRLEKIVLA 663
A Q+ + ++ + ++ DEIQ L L+ Q + RL+K +LA
Sbjct: 893 ADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLA 945
Score = 43.2 bits (97), Expect = 0.003
Identities = 60/269 (22%), Positives = 121/269 (44%), Gaps = 29/269 (10%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
DEI+ LR +AL+ + E D R K + ++L E ++ N+ D + R+
Sbjct: 918 DEIQRLR------QALQASQAERDTARLDKELLAQRLQGLE---QEAENKKRSQDDRARQ 968
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ L V LE + +++ +E ++ + ++L+Q+R + Q LE
Sbjct: 969 ----LKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQD--LE 1022
Query: 360 C-KQQIEKLTVQHKSAIQQLEEDLKQTKRA--LQEQCEITKREIELKERTETELQDSRNA 416
C K +E+ K+ + E K + L+ Q ++ + ++ +ER +T LQ +
Sbjct: 1023 CDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK 1082
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG 476
+E K+ EL + + ER+ Q + +LRV + + E+E E G
Sbjct: 1083 LER---KVKEL-----SIQIEDERQ---HVNDQKDQLSLRVKALKRQVDEAEEEIERLDG 1131
Query: 477 IQQKLAAELLNKEEIIGKMQIQTRELIKN 505
+++K E+ + E+ ++Q + + L K+
Sbjct: 1132 LRKKAQREVEEQHEVNEQLQARIKSLEKD 1160
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 80.2 bits (189), Expect = 2e-14
Identities = 92/482 (19%), Positives = 214/482 (44%), Gaps = 24/482 (4%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 906 ERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 965
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQ--L 297
++ + + +EN K L E LD E AKL+ KEK E+ + + A+ DK L
Sbjct: 966 KVEKQKHATENKVKNLTEEMAGLD-ETIAKLS-KEKKALQETHQQTLDDLQAEEDKVNIL 1023
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + +T + + L ++
Sbjct: 1024 TKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKL 1083
Query: 358 LECKQQIEKL--TVQHKSAIQ-QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ + +I L ++ + A++ QL++ +K+ + ++E E + E + + E + D
Sbjct: 1084 EKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLS 1143
Query: 415 NAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESEN 473
+EE+ ++ E + +L +RE + + +L+ E + + + R+K +++
Sbjct: 1144 RELEEISERLEEAGGATSAQVELNKKREAE-FQKLRRDLEEATLQHEAMVAALRKKHADS 1202
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH-NRTIAN 532
+L ++ N + + K++ + EL K+ + + + + H + +
Sbjct: 1203 ----MAELGEQIDNLQRVKQKLEKEKSEL----KMETDDLSSNAEAISKAKGHLEKMCRS 1254
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK 592
++ +G+ ++ +Q+ + + D+ + L + ++L++QD +R +
Sbjct: 1255 LEDQVSGLKTKEEEQQRL-----INDLTAQRARLQTEAGEYSRQLDEQDALVSQLSRSKQ 1309
Query: 593 IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+ I LK++ E+++ AL L+ D + +Q + + EL L
Sbjct: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1369
Query: 653 QI 654
++
Sbjct: 1370 EV 1371
Score = 77.0 bits (181), Expect = 2e-13
Identities = 84/437 (19%), Positives = 194/437 (44%), Gaps = 32/437 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E + K++L +E++ ++ ++ + K+ +
Sbjct: 838 KIKPLLKSAETEKEMATMKEEFQKT-------KDELAKSEAKRKELEEKMVTLLKEKNDL 890
Query: 301 EASITSLTGTVKMLEDQSRQ---KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + S ++ E++ Q ++QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 891 QLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDEC 950
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + +Q + K +E + + +L + + + + +
Sbjct: 951 SELKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTL 1010
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1011 DDLQAEEDKVNILTKAKTK----LEQQVD---DLEGSLEQEKKLRMDLERAKRKLEGDLK 1063
Query: 475 IGIQQKLAAE--LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
+ + + E +E + K + + LI I+ + IQ ++ +++LQA +
Sbjct: 1064 LAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGE 1123
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-----SEILAKKDQELEQQDKNSRGQ 587
E+ S +++ DL +L ++ R EE +++ K +E E Q K R
Sbjct: 1124 EIEAERA-SRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQ-KLRRDL 1181
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATL 647
E ++ L+ K + +A L + +++ R+ ++ K+ + E +L +
Sbjct: 1182 EEATLQHEAMVAALRKKHAD---SMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNA 1238
Query: 648 ENKQQQIHRLEKIVLAL 664
E + LEK+ +L
Sbjct: 1239 EAISKAKGHLEKMCRSL 1255
Score = 66.9 bits (156), Expect = 2e-10
Identities = 114/559 (20%), Positives = 220/559 (39%), Gaps = 32/559 (5%)
Query: 118 QEVAQLYRDAIA-SSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYN 176
+ +A+L ++ A T + L+ L NI+ KT L D +G + +
Sbjct: 990 ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRM 1049
Query: 177 D---QGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA---KLRQ 230
D +L G L+ + D N L ++ + + + + E A +L++
Sbjct: 1050 DLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQK 1109
Query: 231 DVETRNVMIDEI-RELRSESENTKALEEMRHELDEE-RTAKLAIKEKLTTTESQLRQTRN 288
++ I+E+ E+ +E + E+ R +L E ++E T +Q+ +
Sbjct: 1110 KIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKK 1169
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQ 348
R A+ K R+ E + V L + +L + L+ + E S+L
Sbjct: 1170 REAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKM 1229
Query: 349 QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTET 408
+ D L + + I K + + LE+ + K +EQ + + R +T
Sbjct: 1230 ETDDLSSNA----EAISKAKGHLEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQT 1285
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKETLRVTEDEVTTC-- 465
E + ++E A + +L +SK E + L E +A + C
Sbjct: 1286 EAGEYSRQLDEQDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDL 1345
Query: 466 ---KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
+ E+E E K +Q+ L+ N E + + +T + + +L E K + Q +++
Sbjct: 1346 LREQYEEEQEGKAELQRALSKA--NSEVAQWRTKYETDAIQRTEELEEAKK-KLAQRLQE 1402
Query: 523 LQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD 581
+ H + A C + Q LQ E+ DL +LDV R+ L KK + ++
Sbjct: 1403 AEEHVEAVNAKCASLEK--TKQRLQNEVEDL---MLDV-ERSNAACAALDKKQRNFDKV- 1455
Query: 582 KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
S + + + + EL + + S EL ++ E + ++ + + EI
Sbjct: 1456 -LSEWKQKYEETQAEL-EASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEIS 1513
Query: 642 ELFATLENKQQQIHRLEKI 660
+L + +QIH LEKI
Sbjct: 1514 DLTEQIAEGGKQIHELEKI 1532
Score = 66.1 bits (154), Expect = 4e-10
Identities = 102/533 (19%), Positives = 233/533 (43%), Gaps = 58/533 (10%)
Query: 138 ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRE----LKTQA 193
E +D ++ ++ K+ L + D + E +S+ ++C +L + LKT+
Sbjct: 1208 EQIDNLQRVKQKLEKEKSELKMETDDLSSNA-EAISKAKGHLEKMCRSLEDQVSGLKTKE 1266
Query: 194 EDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK 253
E+ + DL+ + L E + + ++ ++ ++ ++ RS+ +T+
Sbjct: 1267 EEQQRLINDLTAQRAR-----------LQTEAGEYSRQLDEQDALVSQLS--RSKQASTQ 1313
Query: 254 ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
+EE++H+L+EE AK A+ L ++ R + + + E + +++ V
Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ 1373
Query: 314 ----LEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTV 369
E + Q+ +LE +KL + L+ E + + SL+ + ++E L +
Sbjct: 1374 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLML 1433
Query: 370 ---QHKSAIQQLEEDLKQTKRALQE---QCEITKREIELKER----TETELQDSRNAIEE 419
+ +A L++ + + L E + E T+ E+E ++ TEL +N EE
Sbjct: 1434 DVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
++ L ++ N ++EI E Q + ++ E E + E+E +
Sbjct: 1494 SLDQLETLRRAHKN----LQQEISDLTE-QIAEGGKQIHELEKIKKQVEQEKCEIQAALE 1548
Query: 480 KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNG 539
+ A L ++E I ++Q++ ++ + ++K+ + ++ + L+ ++ + +S
Sbjct: 1549 EAEASLEHEEGKILRIQLELNQVKSEV---DRKIAEKDEEIDQLKRNHTRVVETMQSTLD 1605
Query: 540 ISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELIN 599
+ + + + +K K+ +L+E+ E++ N R A ++
Sbjct: 1606 AEIRS-RNDALRVKKKM------EGDLNEM------EIQLNHAN-RLAAESLRNYRNTQG 1651
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+LK + L Q+DL+ ++ IV+ + A EI+EL+ATLE ++
Sbjct: 1652 ILKETQLHLDDALRG-QEDLKEQLAIVERRANLLQA---EIEELWATLEQTER 1700
Score = 61.3 bits (142), Expect = 1e-08
Identities = 98/471 (20%), Positives = 199/471 (42%), Gaps = 57/471 (12%)
Query: 160 NQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGE 219
N Q D+ E ++ Q EL ++++ + + + + HE ++ +
Sbjct: 1507 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1566
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE---RTAKLAIKEK- 275
L + +++ + + ++ ID+++ +T+ +E M+ LD E R L +K+K
Sbjct: 1567 ELNQVKSEVDRKIAEKDEEIDQLKR-----NHTRVVETMQSTLDAEIRSRNDALRVKKKM 1621
Query: 276 ---LTTTESQLRQTRNRVAKMDKQLREAEASITS----LTGTVKMLEDQSRQKEVQLEAR 328
L E QL A+ + R + + L ++ ED Q + +E R
Sbjct: 1622 EGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI-VERR 1680
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
A L+ ++ T Q + R + E+L+ ++++ L Q+ S I TK+
Sbjct: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN--------TKKK 1732
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
L+ +L+ E +Q+SRNA E+ + I + ++E D A L
Sbjct: 1733 LENDVS------QLQSEVEEVIQESRNAEEKAKKAITDAAMMAEE----LKKEQDTSAHL 1782
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
+ K+ L T K+ ++++ ++LA L ++ I K++ + REL ++
Sbjct: 1783 ERMKKNLEQT---------VKDLQHRLDEAEQLA--LKGGKKQIQKLEARVRELEGEVE- 1830
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANC-----QESPNGISYQDLQQEIMDLKMKLLDVVHRN 563
NEQK + + V+ L+ H+R + ++ N + QDL ++
Sbjct: 1831 NEQK--RNAEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEA 1888
Query: 564 EELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
EE S K ++L+ + + + +A I E +N L+ K E +++A
Sbjct: 1889 EEQSNANLSKFRKLQHELEEAEERA---DIAESQVNKLRVKSREVHTKISA 1936
>BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.
Length = 1843
Score = 80.2 bits (189), Expect = 2e-14
Identities = 105/464 (22%), Positives = 209/464 (45%), Gaps = 37/464 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLT 277
+ L+ L +E D++ EL E+ KA L +M E D +R + E+
Sbjct: 354 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Query: 278 TTESQLRQTRNRVAKMDKQLRE-------AEASITSLTGTVKMLEDQSRQKEVQLEARA- 329
T E +Q+ + + +L + +EA SL V L SR ++++E ++
Sbjct: 414 TLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTS-SRLLKLEMENQSL 472
Query: 330 ----RKLRESLKTGEVTTSQLIQ-----QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+LR ++ + E S++++ QR S + E+LE + EK ++Q+ Q L +
Sbjct: 473 TKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN---CQNLSK 529
Query: 381 DLKQTKRALQEQCEI----TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
DL + K L++ E ++R+I++ E+ L + +++ + +++I + K D+
Sbjct: 530 DLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ-RSQISAEARVK---DI 585
Query: 437 PTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ 496
E +I L ++ T L E E K+E E + G + A EL N+ + K
Sbjct: 586 EKENKI-LHESIKETSSKLSKIEFEKRQIKKELEHYKEKG---ERAEELENELHHLEKEN 641
Query: 497 IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKM 554
++ I N+K+ +K+ EQ +L+ NR + +S +++Q L++E L
Sbjct: 642 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 701
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ L++ RN E + + K +L+ ++K + +K EL+ K
Sbjct: 702 ENLEL-RRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 760
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
L + + + ++ NK+I E+Q+L + Q+ + L+
Sbjct: 761 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK 804
Score = 77.4 bits (182), Expect = 2e-13
Identities = 93/446 (20%), Positives = 210/446 (47%), Gaps = 37/446 (8%)
Query: 219 EALVREVAKLRQ-DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTA--KLAIKEK 275
E++ +KL + + E R + E+ + + E + LE H L++E K K
Sbjct: 594 ESIKETSSKLSKIEFEKRQIK-KELEHYKEKGERAEELENELHHLEKENELLQKKITNLK 652
Query: 276 LTTTESQ-LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRE 334
+T + + L Q + + + +++L++ S +LT ++ LE ++ Q + + R+ E
Sbjct: 653 ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEE-NLELRRNVE 711
Query: 335 SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE---EDLKQTKRALQE 391
SLK + +QL + L++E + K+ +E L K ++LE + L + LQ+
Sbjct: 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKT-ERLEVSYQGLDIENQRLQK 770
Query: 392 QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
E + ++I+ + E+ELQD + LQ + EL+ S + +L+
Sbjct: 771 TLENSNKKIQ---QLESELQDLEMENQTLQKNLEELKISSKRLE-----------QLEKE 816
Query: 452 KETLRVTEDEVTTCKREKESENK-IGIQQKLAAELLNKEEI-IGKMQIQTRELIKNIKLN 509
++L ++ K++ E ENK + Q ++ L + + IG ++ + + L K I +
Sbjct: 817 NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIY 876
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
++ ++ +++L+ N+ + + + + + L+++++ K+K + + E+L+
Sbjct: 877 KESCVR----LKELEKENKELVK-RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931
Query: 570 LAK--KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
L K ++E D+ S +R + +L + LK + ++AAL+ LE
Sbjct: 932 LEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEES----T 987
Query: 628 EVNKQIAAKADEIQELFATLENKQQQ 653
N+Q+ + +++ + L+ +Q +
Sbjct: 988 NYNQQLRQELKTVKKNYEALKQRQDE 1013
Score = 64.9 bits (151), Expect = 9e-10
Identities = 108/519 (20%), Positives = 234/519 (45%), Gaps = 45/519 (8%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D LE +D+ EL +LK + D + D+ ++ E + E + E+A
Sbjct: 365 DQLEGTRARSDKLHELEKENLQLKAKLHD-MEMERDMDRKKIEE-----LMEENMTLEMA 418
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEE-MRHELDE---ERTAKLAIK-EKLTTTES 281
+ +Q ++ + E+ ++ SE ++A ++ + HE++E R KL ++ + LT T
Sbjct: 419 Q-KQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 477
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL---KT 338
+LR T + V ++ + E L+ V++LE++ Q++ L+ + L + L K
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ-NCQNLSKDLMKEKA 536
Query: 339 GEVTTSQLIQQRDSLQAEVLE-----CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
T + +++ Q ++LE Q + L + + + + +D+++ + L E
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESI 596
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE 453
+ T ++ E + +++ +E + ELE + + E L+ T E
Sbjct: 597 KETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 656
Query: 454 TLRVTEDEVTTCKREKESENK-IGIQQKLAAEL--LNKEEI-IGKMQIQTRELIKNIKLN 509
+ E E + +RE K + + L +L L KE + + ++ R ++++K
Sbjct: 657 KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCA 716
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNG---------ISYQDLQQEIMDLKMKLLDVV 560
K+ Q + ++L++ + E +SYQ L E L+ K L+
Sbjct: 717 SMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ-KTLE-- 773
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
+ N+++ + L + Q+LE +++ + +KI + + L+ + +E + L++D +
Sbjct: 774 NSNKKIQQ-LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKK 832
Query: 621 HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+++ NK++ +A EI++ TLE +I LEK
Sbjct: 833 Q----LEKENKRLRQQA-EIKD--TTLEENNVKIGNLEK 864
Score = 53.6 bits (123), Expect = 2e-06
Identities = 103/485 (21%), Positives = 211/485 (43%), Gaps = 48/485 (9%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L+EL+ + ++ V KRA + +TL+ + E LV E K +Q +
Sbjct: 878 ESCVRLKELEKENKELV-------KRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Query: 241 EIRELRSESE----NTKALEEMRHELDE---ERTAK--LAIK-EKLTTTESQLRQTRNRV 290
E+ ++ E + ++ ++ R++L E E T K L IK EK+ E++L ++ N
Sbjct: 931 ELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTN-- 988
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
++QLR+ ++ +K +D+ R + + ++ E TT +L++ +
Sbjct: 989 --YNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQE-TTRELLKVK 1045
Query: 351 D----------SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI 400
D +LQAE K Q+++L Q+ + Q+ +QT ++ + +
Sbjct: 1046 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1105
Query: 401 ELKERTETELQDSRNAI-EELQAKIIELEKSKPNPDLPTERE--IDLWAELQATKETL-- 455
+L+ T S + + + Q I + N + ERE L+ L E L
Sbjct: 1106 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1165
Query: 456 ----RVTEDEVTTCKRE--KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ +E E K K + + ++ + +L ++ + K + Q +L K +K+
Sbjct: 1166 LHERQASEYESLISKHGTLKSAHKNLEVEHR---DLEDRYNQLLKQKGQLEDLEKMLKVE 1222
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSE 568
++K++ + + A + + + N Q L++ E++ K L + N +L +
Sbjct: 1223 QEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQ 1282
Query: 569 I-LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
L + +L++Q + + + + EL++ LK E++R L Q L + R +
Sbjct: 1283 TRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLL 1342
Query: 628 EVNKQ 632
E N +
Sbjct: 1343 EQNME 1347
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/433 (17%), Positives = 189/433 (43%), Gaps = 27/433 (6%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNR 289
D +T+ + I+E+ EN L+ M ++ +E L + + +L R+
Sbjct: 149 DFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLL--KNMALHLKRLIDERDE 206
Query: 290 VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
++ +L E + L + ++ + L L + +L Q+
Sbjct: 207 HSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQE 266
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITKREIELKERTE 407
+ ++L+CKQ++E++ ++ K Q+ L + R +++ + + + ++ E
Sbjct: 267 LEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLE 326
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
+E+ + + +++ +E+ K + + E + L +L+ T R D++
Sbjct: 327 SEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT----RARSDKL----H 378
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
E E EN + ++ KL + ++ K++ E + +Q + + +L+ +
Sbjct: 379 ELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Query: 528 RTIANCQESPNGISYQDLQQEIMDL-KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
RT + E+P + L E+ +L +LL + N+ L++ + + ++ + N+
Sbjct: 438 RT-SELSEAPQ----KSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA-- 490
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++++K+ +E + K E ++ E+ +Q L++ + ++ K+ A I+ L
Sbjct: 491 -SKILKMEKENQRLSKKVEILEN-EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL--- 545
Query: 647 LENKQQQIHRLEK 659
EN ++QI LE+
Sbjct: 546 RENSERQIKILEQ 558
Score = 44.0 bits (99), Expect = 0.002
Identities = 62/321 (19%), Positives = 140/321 (43%), Gaps = 19/321 (5%)
Query: 119 EVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQ 178
++ L R ++ L+ + + +EN ++ +NQ+ +L S ++
Sbjct: 1082 QILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN---AQLLIQQSSLENE 1138
Query: 179 GFELCGALRELKTQAEDAVNTVTDLS---KRACHERRTLIAVGEALVREVAKLRQDVETR 235
+ +LK+ + + L +R E +LI+ L + A +VE R
Sbjct: 1139 NESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTL--KSAHKNLEVEHR 1196
Query: 236 NVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++ D +L + + LE+M E+ + E + +L +R+
Sbjct: 1197 DLE-DRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYS 1255
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
QL + + + +K L + S+ ++ +LEA KL+E + ++T+++L Q + L
Sbjct: 1256 QLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLS- 1314
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE-LQDSR 414
+ K +E+ +++ + Q++ + Q + L++ E +K +++R + L + R
Sbjct: 1315 ---QLKGNLEE---ENRHLLDQIQTLMLQNRTLLEQNME-SKDLFHVEQRQYIDKLNELR 1367
Query: 415 NAIEELQAKIIELEK-SKPNP 434
E+L+ KI++ K P+P
Sbjct: 1368 RQKEKLEEKIMDQYKFYDPSP 1388
>BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein.
Length = 887
Score = 80.2 bits (189), Expect = 2e-14
Identities = 105/464 (22%), Positives = 209/464 (45%), Gaps = 37/464 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLT 277
+ L+ L +E D++ EL E+ KA L +M E D +R + E+
Sbjct: 351 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 410
Query: 278 TTESQLRQTRNRVAKMDKQLRE-------AEASITSLTGTVKMLEDQSRQKEVQLEARA- 329
T E +Q+ + + +L + +EA SL V L SR ++++E ++
Sbjct: 411 TLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTS-SRLLKLEMENQSL 469
Query: 330 ----RKLRESLKTGEVTTSQLIQ-----QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+LR ++ + E S++++ QR S + E+LE + EK ++Q+ Q L +
Sbjct: 470 TKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN---CQNLSK 526
Query: 381 DLKQTKRALQEQCEI----TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
DL + K L++ E ++R+I++ E+ L + +++ + +++I + K D+
Sbjct: 527 DLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ-RSQISAEARVK---DI 582
Query: 437 PTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ 496
E +I L ++ T L E E K+E E + G + A EL N+ + K
Sbjct: 583 EKENKI-LHESIKETSSKLSKIEFEKRQIKKELEHYKEKG---ERAEELENELHHLEKEN 638
Query: 497 IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKM 554
++ I N+K+ +K+ EQ +L+ NR + +S +++Q L++E L
Sbjct: 639 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 698
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ L++ RN E + + K +L+ ++K + +K EL+ K
Sbjct: 699 ENLEL-RRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 757
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
L + + + ++ NK+I E+Q+L + Q+ + L+
Sbjct: 758 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK 801
Score = 64.9 bits (151), Expect = 9e-10
Identities = 108/519 (20%), Positives = 234/519 (45%), Gaps = 45/519 (8%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D LE +D+ EL +LK + D + D+ ++ E + E + E+A
Sbjct: 362 DQLEGTRARSDKLHELEKENLQLKAKLHD-MEMERDMDRKKIEE-----LMEENMTLEMA 415
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEE-MRHELDE---ERTAKLAIK-EKLTTTES 281
+ +Q ++ + E+ ++ SE ++A ++ + HE++E R KL ++ + LT T
Sbjct: 416 Q-KQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 474
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL---KT 338
+LR T + V ++ + E L+ V++LE++ Q++ L+ + L + L K
Sbjct: 475 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ-NCQNLSKDLMKEKA 533
Query: 339 GEVTTSQLIQQRDSLQAEVLE-----CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
T + +++ Q ++LE Q + L + + + + +D+++ + L E
Sbjct: 534 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESI 593
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE 453
+ T ++ E + +++ +E + ELE + + E L+ T E
Sbjct: 594 KETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 653
Query: 454 TLRVTEDEVTTCKREKESENK-IGIQQKLAAEL--LNKEEI-IGKMQIQTRELIKNIKLN 509
+ E E + +RE K + + L +L L KE + + ++ R ++++K
Sbjct: 654 KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCA 713
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNG---------ISYQDLQQEIMDLKMKLLDVV 560
K+ Q + ++L++ + E +SYQ L E L+ K L+
Sbjct: 714 SMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ-KTLE-- 770
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
+ N+++ + L + Q+LE +++ + +KI + + L+ + +E + L++D +
Sbjct: 771 NSNKKIQQ-LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKK 829
Query: 621 HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+++ NK++ +A EI++ TLE +I LEK
Sbjct: 830 Q----LEKENKRLRQQA-EIKD--TTLEENNVKIGNLEK 861
Score = 61.7 bits (143), Expect = 9e-09
Identities = 68/309 (22%), Positives = 146/309 (47%), Gaps = 26/309 (8%)
Query: 219 EALVREVAKLRQ-DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTA--KLAIKEK 275
E++ +KL + + E R + E+ + + E + LE H L++E K K
Sbjct: 591 ESIKETSSKLSKIEFEKRQIK-KELEHYKEKGERAEELENELHHLEKENELLQKKITNLK 649
Query: 276 LTTTESQ-LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRE 334
+T + + L Q + + + +++L++ S +LT ++ LE ++ Q + + R+ E
Sbjct: 650 ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEE-NLELRRNVE 708
Query: 335 SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE---EDLKQTKRALQE 391
SLK + +QL + L++E + K+ +E L K ++LE + L + LQ+
Sbjct: 709 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKT-ERLEVSYQGLDIENQRLQK 767
Query: 392 QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
E + ++I+ + E+ELQD + LQ + EL+ S + +L+
Sbjct: 768 TLENSNKKIQ---QLESELQDLEMENQTLQKNLEELKISSKRLE-----------QLEKE 813
Query: 452 KETLRVTEDEVTTCKREKESENK-IGIQQKLAAELLNKEEI-IGKMQIQTRELIKNIKLN 509
++L ++ K++ E ENK + Q ++ L + + IG ++ + + L K I +
Sbjct: 814 NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIY 873
Query: 510 EQKVIQYEQ 518
++ ++ ++
Sbjct: 874 KESCVRLKE 882
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/433 (17%), Positives = 189/433 (43%), Gaps = 27/433 (6%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNR 289
D +T+ + I+E+ EN L+ M ++ +E L + + +L R+
Sbjct: 146 DFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLL--KNMALHLKRLIDERDE 203
Query: 290 VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
++ +L E + L + ++ + L L + +L Q+
Sbjct: 204 HSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQE 263
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITKREIELKERTE 407
+ ++L+CKQ++E++ ++ K Q+ L + R +++ + + + ++ E
Sbjct: 264 LEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLE 323
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
+E+ + + +++ +E+ K + + E + L +L+ T R D++
Sbjct: 324 SEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT----RARSDKL----H 375
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
E E EN + ++ KL + ++ K++ E + +Q + + +L+ +
Sbjct: 376 ELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 434
Query: 528 RTIANCQESPNGISYQDLQQEIMDL-KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
RT + E+P + L E+ +L +LL + N+ L++ + + ++ + N+
Sbjct: 435 RT-SELSEAPQ----KSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA-- 487
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++++K+ +E + K E ++ E+ +Q L++ + ++ K+ A I+ L
Sbjct: 488 -SKILKMEKENQRLSKKVEILEN-EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL--- 542
Query: 647 LENKQQQIHRLEK 659
EN ++QI LE+
Sbjct: 543 RENSERQIKILEQ 555
>AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22037 fis, clone HEP08868. ).
Length = 746
Score = 80.2 bits (189), Expect = 2e-14
Identities = 105/501 (20%), Positives = 225/501 (44%), Gaps = 36/501 (7%)
Query: 170 EHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLR 229
E L + Q EL ++EL+ + DL+ + E+ L+ E L + K +
Sbjct: 46 EELRKAMAQTQELVNKVKELEEKTATLSQEKNDLTIQLQAEQENLMDAEERLTW-MMKTK 104
Query: 230 QDVETRNVMIDEIRELRSESEN-----TKALEEMRHELDEERTAKLAIKEKLTTTESQLR 284
D+E++ I ++RE E E + A ++ EL + + ++ L TE + +
Sbjct: 105 MDLESQ---ISDMRERLEEEEGMAASLSAAKRKLEGELSDLKRDLEGLETTLAKTEKEKQ 161
Query: 285 QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTS 344
++V + L E SIT L + LE+ ++ L+A K+ K ++
Sbjct: 162 ALDHKVRTLTGDLSLREDSITKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKNNSKLST 221
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT-KREIELK 403
Q+ + D+ + E + + ++EK + +S ++ ++L + +R+ + E+ KR++E+
Sbjct: 222 QIHELEDNWEQE-KKIRAEVEKARRKAESDLKMTIDNLNEMERSKLDLEEVVKKRDLEIN 280
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAE--LQATKETLRVTEDE 461
++ +D ++ LQ K+ K + D E E +L AE ++A E R E E
Sbjct: 281 S-VNSKYEDEQSLNSTLQRKL------KEHQDRIEELEEELEAERAMRAKIEQNRKREAE 333
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR-ELIKNIKLNEQKVIQ-YEQY 519
+ +RE E + +Q + A L K+ + ++ E ++ +K +K Q +
Sbjct: 334 LLKLRRELE---EAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEKDKQVMKAE 390
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI---LAKKDQE 576
+ DL A TI + + + L+ + + K+ ++ E++ I L ++ E
Sbjct: 391 IDDLNASMETIQKSKMNAEA-HVRKLEDSLSEANAKVAELERNQAEINAIRTRLQAENSE 449
Query: 577 LEQQDKNSRGQA-RVIKIREELINVLKN-----KETEQSRELAALQ-QDLEHRMRIVDEV 629
L ++ + S+ + ++++I+ L + + + E +SR A + + +H + +V E
Sbjct: 450 LSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQ 509
Query: 630 NKQIAAKADEIQELFATLENK 650
++ E+Q L + L +
Sbjct: 510 LEEEQGGKSELQRLVSKLNTE 530
Score = 66.5 bits (155), Expect = 3e-10
Identities = 78/407 (19%), Positives = 171/407 (42%), Gaps = 20/407 (4%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
+E++ E +LR+ + ++ +++E E +L+ L Q + ++ L +L
Sbjct: 38 EEEMKAKEEELRKAMAQTQELVNKVKELEEKTATLSQEKNDLTIQLQAEQENLMDAEERL 97
Query: 333 RESLKTGEVTTSQLIQQRDSLQ------AEVLECKQQIEKLTVQHKSAIQQLEEDLKQT- 385
+KT SQ+ R+ L+ A + K+++E K ++ LE L +T
Sbjct: 98 TWMMKTKMDLESQISDMRERLEEEEGMAASLSAAKRKLEGELSDLKRDLEGLETTLAKTE 157
Query: 386 --KRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI---IELEKSKPNPDLPTER 440
K+AL + ++ L+E + T+LQ + A+EEL K ++ E+ K N
Sbjct: 158 KEKQALDHKVRTLTGDLSLREDSITKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKNNS 217
Query: 441 EIDLWA-ELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELLNKEEIIGKMQI 497
++ EL+ E + EV +R+ ES+ K+ I ++ L+ EE++ K +
Sbjct: 218 KLSTQIHELEDNWEQEKKIRAEVEKARRKAESDLKMTIDNLNEMERSKLDLEEVVKKRDL 277
Query: 498 QTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLL 557
+ + N K +++ + R L+ H I +E + + ++ +I + +
Sbjct: 278 EINSV--NSKYEDEQSLN-STLQRKLKEHQDRIEELEEELE--AERAMRAKIEQNRKREA 332
Query: 558 DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ 617
+++ EL E + + K + E + +K+K + + + A
Sbjct: 333 ELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEKDKQVMKAEID 392
Query: 618 DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
DL M + + A ++++ + K ++ R + + A+
Sbjct: 393 DLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVAELERNQAEINAI 439
Score = 64.9 bits (151), Expect = 9e-10
Identities = 109/518 (21%), Positives = 221/518 (42%), Gaps = 38/518 (7%)
Query: 158 TVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAV 217
T++ Q + D + HL++ N + L + Q + V ++A + + I
Sbjct: 198 TLDDLQAEEDKVNHLTKNNSKLSTQIHELEDNWEQEKKIRAEVEKARRKAESDLKMTIDN 257
Query: 218 GEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEE-MRHELDEERTAKLAIKEKL 276
+ R L + V+ R++ EI + S+ E+ ++L ++ +L E + ++E+L
Sbjct: 258 LNEMERSKLDLEEVVKKRDL---EINSVNSKYEDEQSLNSTLQRKLKEHQDRIEELEEEL 314
Query: 277 TTTES---QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLR 333
+ ++ Q R R A++ K RE E + T L R+K V A +
Sbjct: 315 EAERAMRAKIEQNRKREAELLKLRRELEEAALQSEATASTL----RKKHVDSMAELTEHV 370
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECK---QQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
ESL+ S+L + + ++AE+ + + I+K + ++ +++LE+ L + +
Sbjct: 371 ESLQR---VKSKLEKDKQVMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVA 427
Query: 391 EQCEITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE---REIDLWA 446
E E + EI ++ R + E + EE Q+++ ++ + K + + R++D +
Sbjct: 428 E-LERNQAEINAIRTRLQAENSELSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEES 486
Query: 447 ELQATKE-TLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
+ ++T +L T+ ++ K + E E + + LN E + + +T + +
Sbjct: 487 KSRSTAVVSLANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRT 546
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGI--SYQDLQQEIMDLKMKLLDVVHRN 563
+L E K + LQ Q + + Q LQ E+ DL + L
Sbjct: 547 EELEETK----RKLAARLQEAEEAAETAQARAASLEKNKQRLQAEVEDLTIDLEKANAAA 602
Query: 564 EELSEILAKKDQEL-EQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
L + D+ L E Q K Q V ++E + TE + A ++ LEH
Sbjct: 603 AALDKKQRLFDKMLAEWQQKCEELQVEVDSSQKECRMYM----TESFKIKTAYEESLEH- 657
Query: 623 MRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
++ V K+ +EI++L L + +H L+K+
Sbjct: 658 ---LESVKKENKTLQEEIKDLIDQLGEGGRSVHELQKL 692
Score = 50.0 bits (114), Expect = 3e-05
Identities = 63/313 (20%), Positives = 137/313 (43%), Gaps = 31/313 (9%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
+R+L+ +A V +L + + A+ L E ++L ++ E +++I L
Sbjct: 412 VRKLEDSLSEANAKVAELERNQAE----INAIRTRLQAENSELSREYEESQSRLNQI--L 465
Query: 246 RSESENTKALEEMRHELDEER----TAKLAI---KEKLTTTESQLRQTRNRVAKMDKQLR 298
R ++ T +++ + +LDEE TA +++ K L + QL + + +++ + +
Sbjct: 466 RIKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQLEEEQGGKSELQRLVS 525
Query: 299 EAEASITSL-----TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSL 353
+ +T+ T ++ E+ K +L AR ++ E+ +T + + L + + L
Sbjct: 526 KLNTEVTTWRTKYETDAIQRTEELEETKR-KLAARLQEAEEAAETAQARAASLEKNKQRL 584
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERT----ETE 409
QAEV + +EK +A+ + + + Q++CE + E++ ++ TE
Sbjct: 585 QAEVEDLTIDLEKANAA-AAALDKKQRLFDKMLAEWQQKCEELQVEVDSSQKECRMYMTE 643
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA-------ELQATKETLRVTEDEV 462
+ A EE + ++K + ID ELQ K+ L + ++E+
Sbjct: 644 SFKIKTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVHELQKLKKKLEMEKEEL 703
Query: 463 TTCKREKESENKI 475
E ES ++
Sbjct: 704 QVALEEAESSLEV 716
>AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein.
Length = 742
Score = 80.2 bits (189), Expect = 2e-14
Identities = 105/464 (22%), Positives = 209/464 (45%), Gaps = 37/464 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLT 277
+ L+ L +E D++ EL E+ KA L +M E D +R + E+
Sbjct: 279 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 338
Query: 278 TTESQLRQTRNRVAKMDKQLRE-------AEASITSLTGTVKMLEDQSRQKEVQLEARA- 329
T E +Q+ + + +L + +EA SL V L SR ++++E ++
Sbjct: 339 TLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTS-SRLLKLEMENQSL 397
Query: 330 ----RKLRESLKTGEVTTSQLIQ-----QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+LR ++ + E S++++ QR S + E+LE + EK ++Q+ Q L +
Sbjct: 398 TKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN---CQNLSK 454
Query: 381 DLKQTKRALQEQCEI----TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
DL + K L++ E ++R+I++ E+ L + +++ + +++I + K D+
Sbjct: 455 DLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ-RSQISAEARVK---DI 510
Query: 437 PTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ 496
E +I L ++ T L E E K+E E + G + A EL N+ + K
Sbjct: 511 EKENKI-LHESIKETSSKLSKIEFEKRQIKKELEHYKEKG---ERAEELENELHHLEKEN 566
Query: 497 IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKM 554
++ I N+K+ +K+ EQ +L+ NR + +S +++Q L++E L
Sbjct: 567 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 626
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ L++ RN E + + K +L+ ++K + +K EL+ K
Sbjct: 627 ENLEL-RRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 685
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
L + + + ++ NK+I E+Q+L + Q+ + L+
Sbjct: 686 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK 729
Score = 57.6 bits (133), Expect = 1e-07
Identities = 88/431 (20%), Positives = 190/431 (44%), Gaps = 31/431 (7%)
Query: 241 EIRELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+IR LR E E T+ L + + EL++ ++++ S R R ++D LRE
Sbjct: 184 KIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDA-LRE 242
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ L V +++ E +AR +L+E + T + L Q + +A +
Sbjct: 243 KAVRVDKLESEVSRYKERLHDIEFY-KARVEELKEDNQVLLETKTMLEDQLEGTRARS-D 300
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
++EK +Q K+ + +E + ++ ++E E + L+ + + +S + E
Sbjct: 301 KLHELEKENLQLKAKLHDMEMERDMDRKKIEELME---ENMTLEMAQKQSMDESLHLGWE 357
Query: 420 LQ--AKIIELEKSKPNPDLPTE-REI--DLWAELQATKETLRVTEDEV-TTCKREKESEN 473
L+ ++ EL ++ P L E E+ +L+ ++L T +E+ TT + + +
Sbjct: 358 LEQISRTSELSEA-PQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNAS 416
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK-----LNEQKVIQYEQYVRDLQAHNR 528
KI +K L K EI+ +Q ++ ++N + L ++K Q E+ + L+ ++
Sbjct: 417 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA-QLEKTIETLRENSE 475
Query: 529 TIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQA 588
E N + L Q + L+ + + + +I K+++ L + K + +
Sbjct: 476 RQIKILEQEN----EHLNQTVSSLRQR--SQISAEARVKDI-EKENKILHESIKETSSKL 528
Query: 589 RVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
I+ + I KE E +E ++LE+ + +++ N+ + K ++ +E
Sbjct: 529 SKIEFEKRQIK----KELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIE 584
Query: 649 NKQQQIHRLEK 659
+Q+ LE+
Sbjct: 585 ALEQENSELER 595
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/433 (17%), Positives = 189/433 (43%), Gaps = 27/433 (6%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNR 289
D +T+ + I+E+ EN L+ M ++ +E L + + +L R+
Sbjct: 74 DFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLL--KNMALHLKRLIDERDE 131
Query: 290 VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
++ +L E + L + ++ + L L + +L Q+
Sbjct: 132 HSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQE 191
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITKREIELKERTE 407
+ ++L+CKQ++E++ ++ K Q+ L + R +++ + + + ++ E
Sbjct: 192 LEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLE 251
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
+E+ + + +++ +E+ K + + E + L +L+ T R D++
Sbjct: 252 SEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT----RARSDKL----H 303
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
E E EN + ++ KL + ++ K++ E + +Q + + +L+ +
Sbjct: 304 ELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 362
Query: 528 RTIANCQESPNGISYQDLQQEIMDL-KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
RT + E+P + L E+ +L +LL + N+ L++ + + ++ + N+
Sbjct: 363 RT-SELSEAPQ----KSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA-- 415
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++++K+ +E + K E ++ E+ +Q L++ + ++ K+ A I+ L
Sbjct: 416 -SKILKMEKENQRLSKKVEILEN-EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL--- 470
Query: 647 LENKQQQIHRLEK 659
EN ++QI LE+
Sbjct: 471 RENSERQIKILEQ 483
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 80.2 bits (189), Expect = 2e-14
Identities = 105/464 (22%), Positives = 209/464 (45%), Gaps = 37/464 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLT 277
+ L+ L +E D++ EL E+ KA L +M E D +R + E+
Sbjct: 354 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Query: 278 TTESQLRQTRNRVAKMDKQLRE-------AEASITSLTGTVKMLEDQSRQKEVQLEARA- 329
T E +Q+ + + +L + +EA SL V L SR ++++E ++
Sbjct: 414 TLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTS-SRLLKLEMENQSL 472
Query: 330 ----RKLRESLKTGEVTTSQLIQ-----QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+LR ++ + E S++++ QR S + E+LE + EK ++Q+ Q L +
Sbjct: 473 TKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN---CQNLSK 529
Query: 381 DLKQTKRALQEQCEI----TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
DL + K L++ E ++R+I++ E+ L + +++ + +++I + K D+
Sbjct: 530 DLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ-RSQISAEARVK---DI 585
Query: 437 PTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ 496
E +I L ++ T L E E K+E E + G + A EL N+ + K
Sbjct: 586 EKENKI-LHESIKETSSKLSKIEFEKRQIKKELEHYKEKG---ERAEELENELHHLEKEN 641
Query: 497 IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKM 554
++ I N+K+ +K+ EQ +L+ NR + +S +++Q L++E L
Sbjct: 642 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 701
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ L++ RN E + + K +L+ ++K + +K EL+ K
Sbjct: 702 ENLEL-RRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 760
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
L + + + ++ NK+I E+Q+L + Q+ + L+
Sbjct: 761 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK 804
Score = 72.5 bits (170), Expect = 5e-12
Identities = 93/446 (20%), Positives = 209/446 (46%), Gaps = 38/446 (8%)
Query: 219 EALVREVAKLRQ-DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTA--KLAIKEK 275
E++ +KL + + E R + E+ + + E + LE H L++E K K
Sbjct: 594 ESIKETSSKLSKIEFEKRQIK-KELEHYKEKGERAEELENELHHLEKENELLQKKITNLK 652
Query: 276 LTTTESQ-LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRE 334
+T + + L Q + + + +++L++ S +LT ++ LE ++ Q + + R+ E
Sbjct: 653 ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEE-NLELRRNVE 711
Query: 335 SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE---EDLKQTKRALQE 391
SLK + +QL + L++E + K+ +E L K ++LE + L + LQ+
Sbjct: 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKT-ERLEVSYQGLDIENQRLQK 770
Query: 392 QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
E + ++I+ + E+ELQD + LQ + EL+ S + +L+
Sbjct: 771 TLENSNKKIQ---QLESELQDLEMENQTLQKNLEELKISSKRLE-----------QLEKE 816
Query: 452 KETLRVTEDEVTTCKREKESENK-IGIQQKLAAELLNKEEI-IGKMQIQTRELIKNIKLN 509
++L ++ K++ E ENK + Q ++ L + + IG ++ + + L K I +
Sbjct: 817 NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIY 876
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
++ ++ +++L+ N+ + + + + + L+++++ K+K + + E+L+
Sbjct: 877 KESCVR----LKELEKENKELVK-RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931
Query: 570 LAK--KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
L K ++E D+ S R + +L + LK + ++AAL+ LE
Sbjct: 932 LEKIGLNKERLLHDEQSTDD-RYKLLESKLESTLKKSLEIKEEKIAALEARLEES----T 986
Query: 628 EVNKQIAAKADEIQELFATLENKQQQ 653
N+Q+ + +++ + L+ +Q +
Sbjct: 987 NYNQQLRQELKTVKKNYEALKQRQDE 1012
Score = 64.9 bits (151), Expect = 9e-10
Identities = 108/519 (20%), Positives = 234/519 (45%), Gaps = 45/519 (8%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D LE +D+ EL +LK + D + D+ ++ E + E + E+A
Sbjct: 365 DQLEGTRARSDKLHELEKENLQLKAKLHD-MEMERDMDRKKIEE-----LMEENMTLEMA 418
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEE-MRHELDE---ERTAKLAIK-EKLTTTES 281
+ +Q ++ + E+ ++ SE ++A ++ + HE++E R KL ++ + LT T
Sbjct: 419 Q-KQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 477
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL---KT 338
+LR T + V ++ + E L+ V++LE++ Q++ L+ + L + L K
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ-NCQNLSKDLMKEKA 536
Query: 339 GEVTTSQLIQQRDSLQAEVLE-----CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
T + +++ Q ++LE Q + L + + + + +D+++ + L E
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESI 596
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE 453
+ T ++ E + +++ +E + ELE + + E L+ T E
Sbjct: 597 KETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 656
Query: 454 TLRVTEDEVTTCKREKESENK-IGIQQKLAAEL--LNKEEI-IGKMQIQTRELIKNIKLN 509
+ E E + +RE K + + L +L L KE + + ++ R ++++K
Sbjct: 657 KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCA 716
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNG---------ISYQDLQQEIMDLKMKLLDVV 560
K+ Q + ++L++ + E +SYQ L E L+ K L+
Sbjct: 717 SMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ-KTLE-- 773
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
+ N+++ + L + Q+LE +++ + +KI + + L+ + +E + L++D +
Sbjct: 774 NSNKKIQQ-LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKK 832
Query: 621 HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+++ NK++ +A EI++ TLE +I LEK
Sbjct: 833 Q----LEKENKRLRQQA-EIKD--TTLEENNVKIGNLEK 864
Score = 54.4 bits (125), Expect = 1e-06
Identities = 102/484 (21%), Positives = 207/484 (42%), Gaps = 47/484 (9%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ---DVETRNV 237
E C L+EL+ + ++ V KRA + +TL+ + E LV E K +Q D+E
Sbjct: 878 ESCVRLKELEKENKELV-------KRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Query: 238 MIDEI-----RELRSESENTKALEEMRHELDEERTAKLAIK-EKLTTTESQLRQTRNRVA 291
+++I R L E + + +L+ L IK EK+ E++L ++ N
Sbjct: 931 ELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTN--- 987
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
++QLR+ ++ +K +D+ R + + ++ E TT +L++ +D
Sbjct: 988 -YNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQE-TTRELLKVKD 1045
Query: 352 ----------SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE 401
+LQAE K Q+++L Q+ + Q+ +QT ++ + + +
Sbjct: 1046 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAK 1105
Query: 402 LKERTETELQDSRNAI-EELQAKIIELEKSKPNPDLPTERE--IDLWAELQATKETL--- 455
L+ T S + + + Q I + N + ERE L+ L E L
Sbjct: 1106 LQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELL 1165
Query: 456 ---RVTEDEVTTCKRE--KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
+ +E E K K + + ++ + +L ++ + K + Q +L K +K+ +
Sbjct: 1166 HERQASEYESLISKHGTLKSAHKNLEVEHR---DLEDRYNQLLKQKGQLEDLEKMLKVEQ 1222
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEI 569
+K++ + + A + + + N Q L++ E++ K L + N +L +
Sbjct: 1223 EKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQT 1282
Query: 570 -LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L + +L++Q + + + + EL++ LK E++R L Q L + R + E
Sbjct: 1283 RLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLE 1342
Query: 629 VNKQ 632
N +
Sbjct: 1343 QNME 1346
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/433 (17%), Positives = 189/433 (43%), Gaps = 27/433 (6%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNR 289
D +T+ + I+E+ EN L+ M ++ +E L + + +L R+
Sbjct: 149 DFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLL--KNMALHLKRLIDERDE 206
Query: 290 VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
++ +L E + L + ++ + L L + +L Q+
Sbjct: 207 HSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQE 266
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITKREIELKERTE 407
+ ++L+CKQ++E++ ++ K Q+ L + R +++ + + + ++ E
Sbjct: 267 LEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLE 326
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
+E+ + + +++ +E+ K + + E + L +L+ T R D++
Sbjct: 327 SEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT----RARSDKL----H 378
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
E E EN + ++ KL + ++ K++ E + +Q + + +L+ +
Sbjct: 379 ELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Query: 528 RTIANCQESPNGISYQDLQQEIMDL-KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
RT + E+P + L E+ +L +LL + N+ L++ + + ++ + N+
Sbjct: 438 RT-SELSEAPQ----KSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA-- 490
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++++K+ +E + K E ++ E+ +Q L++ + ++ K+ A I+ L
Sbjct: 491 -SKILKMEKENQRLSKKVEILEN-EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL--- 545
Query: 647 LENKQQQIHRLEK 659
EN ++QI LE+
Sbjct: 546 RENSERQIKILEQ 558
Score = 44.0 bits (99), Expect = 0.002
Identities = 62/321 (19%), Positives = 140/321 (43%), Gaps = 19/321 (5%)
Query: 119 EVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQ 178
++ L R ++ L+ + + +EN ++ +NQ+ +L S ++
Sbjct: 1081 QILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN---AQLLIQQSSLENE 1137
Query: 179 GFELCGALRELKTQAEDAVNTVTDLS---KRACHERRTLIAVGEALVREVAKLRQDVETR 235
+ +LK+ + + L +R E +LI+ L + A +VE R
Sbjct: 1138 NESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTL--KSAHKNLEVEHR 1195
Query: 236 NVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++ D +L + + LE+M E+ + E + +L +R+
Sbjct: 1196 DLE-DRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYS 1254
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
QL + + + +K L + S+ ++ +LEA KL+E + ++T+++L Q + L
Sbjct: 1255 QLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLS- 1313
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE-LQDSR 414
+ K +E+ +++ + Q++ + Q + L++ E +K +++R + L + R
Sbjct: 1314 ---QLKGNLEE---ENRHLLDQIQTLMLQNRTLLEQNME-SKDLFHVEQRQYIDKLNELR 1366
Query: 415 NAIEELQAKIIELEK-SKPNP 434
E+L+ KI++ K P+P
Sbjct: 1367 RQKEKLEEKIMDQYKFYDPSP 1387
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 80.2 bits (189), Expect = 2e-14
Identities = 105/464 (22%), Positives = 209/464 (45%), Gaps = 37/464 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLT 277
+ L+ L +E D++ EL E+ KA L +M E D +R + E+
Sbjct: 354 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Query: 278 TTESQLRQTRNRVAKMDKQLRE-------AEASITSLTGTVKMLEDQSRQKEVQLEARA- 329
T E +Q+ + + +L + +EA SL V L SR ++++E ++
Sbjct: 414 TLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTS-SRLLKLEMENQSL 472
Query: 330 ----RKLRESLKTGEVTTSQLIQ-----QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+LR ++ + E S++++ QR S + E+LE + EK ++Q+ Q L +
Sbjct: 473 TKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN---CQNLSK 529
Query: 381 DLKQTKRALQEQCEI----TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
DL + K L++ E ++R+I++ E+ L + +++ + +++I + K D+
Sbjct: 530 DLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ-RSQISAEARVK---DI 585
Query: 437 PTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ 496
E +I L ++ T L E E K+E E + G + A EL N+ + K
Sbjct: 586 EKENKI-LHESIKETSSKLSKIEFEKRQIKKELEHYKEKG---ERAEELENELHHLEKEN 641
Query: 497 IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKM 554
++ I N+K+ +K+ EQ +L+ NR + +S +++Q L++E L
Sbjct: 642 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 701
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ L++ RN E + + K +L+ ++K + +K EL+ K
Sbjct: 702 ENLEL-RRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 760
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
L + + + ++ NK+I E+Q+L + Q+ + L+
Sbjct: 761 LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK 804
Score = 77.4 bits (182), Expect = 2e-13
Identities = 93/446 (20%), Positives = 210/446 (47%), Gaps = 37/446 (8%)
Query: 219 EALVREVAKLRQ-DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTA--KLAIKEK 275
E++ +KL + + E R + E+ + + E + LE H L++E K K
Sbjct: 594 ESIKETSSKLSKIEFEKRQIK-KELEHYKEKGERAEELENELHHLEKENELLQKKITNLK 652
Query: 276 LTTTESQ-LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRE 334
+T + + L Q + + + +++L++ S +LT ++ LE ++ Q + + R+ E
Sbjct: 653 ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEE-NLELRRNVE 711
Query: 335 SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE---EDLKQTKRALQE 391
SLK + +QL + L++E + K+ +E L K ++LE + L + LQ+
Sbjct: 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKT-ERLEVSYQGLDIENQRLQK 770
Query: 392 QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
E + ++I+ + E+ELQD + LQ + EL+ S + +L+
Sbjct: 771 TLENSNKKIQ---QLESELQDLEMENQTLQKNLEELKISSKRLE-----------QLEKE 816
Query: 452 KETLRVTEDEVTTCKREKESENK-IGIQQKLAAELLNKEEI-IGKMQIQTRELIKNIKLN 509
++L ++ K++ E ENK + Q ++ L + + IG ++ + + L K I +
Sbjct: 817 NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIY 876
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
++ ++ +++L+ N+ + + + + + L+++++ K+K + + E+L+
Sbjct: 877 KESCVR----LKELEKENKELVK-RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931
Query: 570 LAK--KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
L K ++E D+ S +R + +L + LK + ++AAL+ LE
Sbjct: 932 LEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEES----T 987
Query: 628 EVNKQIAAKADEIQELFATLENKQQQ 653
N+Q+ + +++ + L+ +Q +
Sbjct: 988 NYNQQLRQELKTVKKNYEALKQRQDE 1013
Score = 64.9 bits (151), Expect = 9e-10
Identities = 108/519 (20%), Positives = 234/519 (45%), Gaps = 45/519 (8%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D LE +D+ EL +LK + D + D+ ++ E + E + E+A
Sbjct: 365 DQLEGTRARSDKLHELEKENLQLKAKLHD-MEMERDMDRKKIEE-----LMEENMTLEMA 418
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEE-MRHELDE---ERTAKLAIK-EKLTTTES 281
+ +Q ++ + E+ ++ SE ++A ++ + HE++E R KL ++ + LT T
Sbjct: 419 Q-KQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 477
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL---KT 338
+LR T + V ++ + E L+ V++LE++ Q++ L+ + L + L K
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ-NCQNLSKDLMKEKA 536
Query: 339 GEVTTSQLIQQRDSLQAEVLE-----CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
T + +++ Q ++LE Q + L + + + + +D+++ + L E
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESI 596
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE 453
+ T ++ E + +++ +E + ELE + + E L+ T E
Sbjct: 597 KETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 656
Query: 454 TLRVTEDEVTTCKREKESENK-IGIQQKLAAEL--LNKEEI-IGKMQIQTRELIKNIKLN 509
+ E E + +RE K + + L +L L KE + + ++ R ++++K
Sbjct: 657 KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCA 716
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNG---------ISYQDLQQEIMDLKMKLLDVV 560
K+ Q + ++L++ + E +SYQ L E L+ K L+
Sbjct: 717 SMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQ-KTLE-- 773
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
+ N+++ + L + Q+LE +++ + +KI + + L+ + +E + L++D +
Sbjct: 774 NSNKKIQQ-LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKK 832
Query: 621 HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+++ NK++ +A EI++ TLE +I LEK
Sbjct: 833 Q----LEKENKRLRQQA-EIKD--TTLEENNVKIGNLEK 864
Score = 53.6 bits (123), Expect = 2e-06
Identities = 103/485 (21%), Positives = 211/485 (43%), Gaps = 48/485 (9%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L+EL+ + ++ V KRA + +TL+ + E LV E K +Q +
Sbjct: 878 ESCVRLKELEKENKELV-------KRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Query: 241 EIRELRSESE----NTKALEEMRHELDE---ERTAK--LAIK-EKLTTTESQLRQTRNRV 290
E+ ++ E + ++ ++ R++L E E T K L IK EK+ E++L ++ N
Sbjct: 931 ELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTN-- 988
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
++QLR+ ++ +K +D+ R + + ++ E TT +L++ +
Sbjct: 989 --YNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQE-TTRELLKVK 1045
Query: 351 D----------SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI 400
D +LQAE K Q+++L Q+ + Q+ +QT ++ + +
Sbjct: 1046 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1105
Query: 401 ELKERTETELQDSRNAI-EELQAKIIELEKSKPNPDLPTERE--IDLWAELQATKETL-- 455
+L+ T S + + + Q I + N + ERE L+ L E L
Sbjct: 1106 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1165
Query: 456 ----RVTEDEVTTCKRE--KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ +E E K K + + ++ + +L ++ + K + Q +L K +K+
Sbjct: 1166 LHERQASEYESLISKHGTLKSAHKNLEVEHR---DLEDRYNQLLKQKGQLEDLEKMLKVE 1222
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSE 568
++K++ + + A + + + N Q L++ E++ K L + N +L +
Sbjct: 1223 QEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQ 1282
Query: 569 I-LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
L + +L++Q + + + + EL++ LK E++R L Q L + R +
Sbjct: 1283 TRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLL 1342
Query: 628 EVNKQ 632
E N +
Sbjct: 1343 EQNME 1347
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/433 (17%), Positives = 189/433 (43%), Gaps = 27/433 (6%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNR 289
D +T+ + I+E+ EN L+ M ++ +E L + + +L R+
Sbjct: 149 DFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLL--KNMALHLKRLIDERDE 206
Query: 290 VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
++ +L E + L + ++ + L L + +L Q+
Sbjct: 207 HSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQE 266
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITKREIELKERTE 407
+ ++L+CKQ++E++ ++ K Q+ L + R +++ + + + ++ E
Sbjct: 267 LEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLE 326
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
+E+ + + +++ +E+ K + + E + L +L+ T R D++
Sbjct: 327 SEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT----RARSDKL----H 378
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
E E EN + ++ KL + ++ K++ E + +Q + + +L+ +
Sbjct: 379 ELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Query: 528 RTIANCQESPNGISYQDLQQEIMDL-KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
RT + E+P + L E+ +L +LL + N+ L++ + + ++ + N+
Sbjct: 438 RT-SELSEAPQ----KSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA-- 490
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++++K+ +E + K E ++ E+ +Q L++ + ++ K+ A I+ L
Sbjct: 491 -SKILKMEKENQRLSKKVEILEN-EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL--- 545
Query: 647 LENKQQQIHRLEK 659
EN ++QI LE+
Sbjct: 546 RENSERQIKILEQ 558
Score = 44.0 bits (99), Expect = 0.002
Identities = 62/321 (19%), Positives = 140/321 (43%), Gaps = 19/321 (5%)
Query: 119 EVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQ 178
++ L R ++ L+ + + +EN ++ +NQ+ +L S ++
Sbjct: 1082 QILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN---AQLLIQQSSLENE 1138
Query: 179 GFELCGALRELKTQAEDAVNTVTDLS---KRACHERRTLIAVGEALVREVAKLRQDVETR 235
+ +LK+ + + L +R E +LI+ L + A +VE R
Sbjct: 1139 NESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTL--KSAHKNLEVEHR 1196
Query: 236 NVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++ D +L + + LE+M E+ + E + +L +R+
Sbjct: 1197 DLE-DRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYS 1255
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
QL + + + +K L + S+ ++ +LEA KL+E + ++T+++L Q + L
Sbjct: 1256 QLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLS- 1314
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE-LQDSR 414
+ K +E+ +++ + Q++ + Q + L++ E +K +++R + L + R
Sbjct: 1315 ---QLKGNLEE---ENRHLLDQIQTLMLQNRTLLEQNME-SKDLFHVEQRQYIDKLNELR 1367
Query: 415 NAIEELQAKIIELEK-SKPNP 434
E+L+ KI++ K P+P
Sbjct: 1368 RQKEKLEEKIMDQYKFYDPSP 1388
>X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa
protein.
Length = 976
Score = 79.8 bits (188), Expect = 3e-14
Identities = 109/465 (23%), Positives = 202/465 (43%), Gaps = 32/465 (6%)
Query: 249 SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLR-QTRNRVAKMDKQLREAEASITSL 307
+E TK E R E + EK+ T +LR Q N +M +L+E I L
Sbjct: 194 AEKTKKYEYEREETRQVYMDLNNNIEKMITAHGELRVQAENSRLEMHFKLKEDYEKIQHL 253
Query: 308 TGTVKM-LEDQSRQKE---VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
K + D+ +Q +Q+ + K+++ E + ++ Q + + + KQ
Sbjct: 254 EQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 364 IEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEI-TKREIELKERTETELQDSRNAIEE 419
IEK LT + + L+ + T++AL+E +I TK +L E ET++++S A
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVS-TQKALEEDLQIATKTICQLTEEKETQMEESNKARAA 372
Query: 420 LQAKIIELEKSKPNPD--LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ E E + + + L TE++ L+ ++ L++ E+ E E K+
Sbjct: 373 HSFVVTEFETTVCSLEELLRTEQQ-----RLEKNEDQLKILTMELQKKSSELEEMTKLTN 427
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+++ E L K ++G+ + E + K+ E+ ++ + LQA + + + +
Sbjct: 428 NKEVELEELKK--VLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQL 485
Query: 538 NGI--SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
I S Q +E+ DLK +L + +N EL+ K E ++ + + +K ++
Sbjct: 486 TAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQ 545
Query: 596 ELINVLKNKETEQSRELAALQQ---DLEHRMRIVDEVNKQ----IAAKADEIQE----LF 644
E IN K +E +++ LQ+ L + + V E KQ + K D+ +E L
Sbjct: 546 EDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Query: 645 ATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHEL 689
+ENK + I L++ AL K+ LE EL
Sbjct: 606 KQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELEL 650
Score = 76.2 bits (179), Expect = 4e-13
Identities = 106/499 (21%), Positives = 223/499 (44%), Gaps = 53/499 (10%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV----AKLRQDVETRNVMIDEIR- 243
L ++ D VN + + +K + I L +E+ L++ V T+ + ++++
Sbjct: 288 LLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQI 347
Query: 244 ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT----ESQLRQTRNRVAKMDKQLRE 299
++ + T+ E E ++ R A + + TT E LR + R+ K + QL+
Sbjct: 348 ATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKL--RESL--------KTGEV---TTSQL 346
+ + ++ + + KEV+LE + L +E+L K E T +L
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQEL 467
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQ---HKSAIQQLEEDLKQTK---RALQEQC-EITKRE 399
I + + EV + + Q+ +T + ++ L+ +L+ K L C +++
Sbjct: 468 IGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLEN 527
Query: 400 IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
EL + T + +N E++ + E+ + E E L EL+ +E L+
Sbjct: 528 KELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKR 587
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
DEV CK +K EN +++++ NK + I ++Q + + L K +++ YE
Sbjct: 588 DEVK-CKLDKSEENCNNLRKQVE----NKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK---LLDVVHRNEELSEILAKKDQE 576
V L+ + + ++ I+ Q+EI D K+ LL+ V + + +++ K +E
Sbjct: 643 VNKLELE---LESAKQKFGEIT-DTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKE 698
Query: 577 LEQQ------------DKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
++++ +K+ ++I+ R+ + + K+KE EQS A+L+ +L +
Sbjct: 699 IDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Query: 625 IVDEVNKQIAAKADEIQEL 643
+ V KQ+ + +E ++L
Sbjct: 759 ELLSVKKQLEIEREEKEKL 777
Score = 73.3 bits (172), Expect = 3e-12
Identities = 91/477 (19%), Positives = 206/477 (43%), Gaps = 23/477 (4%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
+C E +TQ E++ S T+ ++ E L E +L ++ + ++ E
Sbjct: 352 ICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTME 411
Query: 242 IRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--- 297
+++ SE E TK EL+E + L KE L Q + + +++L
Sbjct: 412 LQKKSSELEEMTKLTNNKEVELEELKKV-LGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 298 ---REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
RE E + T +Q KEV + L+ L+ ++ ++L + L
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYYSKEV------KDLKTELENEKLKNTELTSHCNKLS 524
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
E E Q+ +T++ K+ + + + KQ +R L++ + + E +L+ E ++ +
Sbjct: 525 LENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELK 584
Query: 415 NAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
+E++ K+ + E++ N E + ELQ + L+ + K+ E K
Sbjct: 585 QKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALK--KKGTAESKQLNVYEIK 642
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ 534
+ KL EL + ++ G++ ++ I++ K++E+ +++ + + + + + +
Sbjct: 643 VN---KLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIA--DEAVKLQK 697
Query: 535 ESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
E ++ + +M+ D + + SE+ K +E EQ + + + +
Sbjct: 698 EIDKRCQHKIAEMVALMEKHKHQYDKIIEERD-SELGLYKSKEQEQSSLRASLEIELSNL 756
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
+ EL++V K E E+ + ++ E+ + ++ +K+ E E++ L++K
Sbjct: 757 KAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIYWKLDSK 813
Score = 57.6 bits (133), Expect = 1e-07
Identities = 93/429 (21%), Positives = 191/429 (44%), Gaps = 57/429 (13%)
Query: 247 SESENTKALEEMRHELDEE----RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
S+ EN++ L + +L +E + K++ + +L ES+L++ R + K ++E +
Sbjct: 94 SDLENSEGLSRVFSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQF 153
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEV 357
++ +K+ E K++ E A + L+E+ T + +R+ +
Sbjct: 154 GNEKVS--LKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVY 211
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
++ IEK+ H Q E + L+E E + L++ + E+ D +
Sbjct: 212 MDLNNNIEKMITAHGELRVQAENSRLEMHFKLKEDYEKIQ---HLEQEYKKEINDKEKQV 268
Query: 418 EELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATK---ETLRVTEDEVTTCKREKESEN 473
L +I E E + E D +L + TK E L+ + ++ +E E +
Sbjct: 269 SLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELE-DI 327
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
K+ +Q+ ++ + +E+ +QI T+ + +L E+K Q E+ + AH+ +
Sbjct: 328 KVSLQRSVSTQKALEED----LQIATKTI---CQLTEEKETQMEESNKARAAHSFVVTEF 380
Query: 534 QESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
+ + + +E++ + + L+ +NE+ +IL +E Q K+S
Sbjct: 381 ETTVCSL------EELLRTEQQRLE---KNEDQLKILT-----MELQKKSSE-------- 418
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI----QELFATLEN 649
EE+ + NKE EL L++ L + ++ E NKQ A+E+ QEL L+
Sbjct: 419 LEEMTKLTNNKEV----ELEELKKVLGEKETLLYE-NKQFEKIAEELKGTEQELIGLLQA 473
Query: 650 KQQQIHRLE 658
+++++H LE
Sbjct: 474 REKEVHDLE 482
Score = 54.0 bits (124), Expect = 2e-06
Identities = 96/442 (21%), Positives = 190/442 (42%), Gaps = 25/442 (5%)
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
E+R+ + + + +SEN K E +H L +E ++ +T+ L + K
Sbjct: 291 ESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATK 350
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
QL E + T + + K S + E L E L+T + + Q
Sbjct: 351 TICQLTEEKE--TQMEESNKARAAHS-FVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 353 LQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
L E+ + ++E KLT + +++L++ L + + L E + K ELK TE E
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELK-GTEQE 466
Query: 410 LQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE 468
L A E E+ I+L + ++ DL EL+ E L+ T E+T+ +
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELE--NEKLKNT--ELTSHCNK 522
Query: 469 KESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIK---NIKLNEQKVIQYEQYVRDL 523
ENK Q+ + EL N++E I + Q ++K N++ E ++ +YVR+
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD-K 582
R C+ + + +L++++ + + ++ N+ L + + ++L + K
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 583 NSRGQARVIKIREEL--INVLKNKETEQSR-ELAALQQDLEHRMRIVDE---VNKQIAAK 636
++ + + +++ I KE E + L +++E I DE + K+I +
Sbjct: 643 VNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKR 702
Query: 637 AD-EIQELFATLENKQQQIHRL 657
+I E+ A +E + Q ++
Sbjct: 703 CQHKIAEMVALMEKHKHQYDKI 724
Score = 37.1 bits (82), Expect = 0.21
Identities = 68/283 (24%), Positives = 132/283 (46%), Gaps = 33/283 (11%)
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI----DLWAELQATKET 454
E EL+++ E++LQ++R IE + I EL+ L E I DL E AT+
Sbjct: 124 EAELRQK-ESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNATRHL 182
Query: 455 LRVTEDEVTTCKREKESENKIGIQQKLAAELL-----NKEEII---GKMQIQTR--ELIK 504
+ ++ TC R E K +++ ++ N E++I G++++Q L
Sbjct: 183 CNLLKE---TCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAHGELRVQAENSRLEM 239
Query: 505 NIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE--IMDLKMKL---LDV 559
+ KL E YE+ Q + + I + ++ + + Q ++E + DL L D
Sbjct: 240 HFKLKE----DYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDK 295
Query: 560 VHRNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELA--ALQ 616
V++ EE +++ ++ Q +E+Q ++ + IK+ + +V K E+ ++A +
Sbjct: 296 VNQLEEKTKLQSENLKQSIEKQHHLTK-ELEDIKVSLQR-SVSTQKALEEDLQIATKTIC 353
Query: 617 QDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
Q E + ++E NK AA + + E F T +++ R E+
Sbjct: 354 QLTEEKETQMEESNKARAAHSFVVTE-FETTVCSLEELLRTEQ 395
>AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 14
isoform protein.
Length = 972
Score = 79.8 bits (188), Expect = 3e-14
Identities = 83/367 (22%), Positives = 166/367 (45%), Gaps = 22/367 (5%)
Query: 154 KTNLTVNQDQTDGDILEHLSRY----NDQGFELCGALRELKTQAED-----AVNTVT-DL 203
K+ +T D+ E ++R N Q EL +E + + ED ++ VT +
Sbjct: 608 KSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEY 667
Query: 204 SKRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR----SESENTKALEEM 258
+A HE+ L V A + L + + +++E+ +L+ ++ EN+ ++ E
Sbjct: 668 IHKAEHEKLMQLTNVSRAKAEDA--LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEH 725
Query: 259 RHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQS 318
+ RTA ++EK++ + L V K++KQL E +A++T E
Sbjct: 726 LQVITTLRTAAKEMEEKISNLKEHLASKEVEVLKLEKQLLEEKAAMTDAMVPRSSYEKLQ 785
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL 378
E ++ A KL+ES+K E S+++Q +++EV + K++ E + KS Q++
Sbjct: 786 SSLESEVSVLASKLKESVKEKEKVHSEVVQ----IRSEVSQVKREKENIQTLLKSKEQEV 841
Query: 379 EEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT 438
E L++ ++A +E E+ KR E + E + N + + K+ E S T
Sbjct: 842 NELLQKFQQAQEELAEM-KRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYST 900
Query: 439 EREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQ 498
+L+A ++ ++ ++++ CK++ + + L A +E + K+ Q
Sbjct: 901 SSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQ 960
Query: 499 TRELIKN 505
+ KN
Sbjct: 961 ILTMCKN 967
Score = 50.4 bits (115), Expect = 2e-05
Identities = 90/476 (18%), Positives = 201/476 (42%), Gaps = 48/476 (10%)
Query: 222 VREVAKLRQDVETRNVMID-EIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTT 279
+++ ++ QD++ R + E ++L+ E ++ +A L + + E ++ L+ +KL T
Sbjct: 423 IQQPQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLS--QKLKET 480
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL-------------- 325
+SQ + V + KQ++ S S+ E + ++E+ +
Sbjct: 481 QSQYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESER 540
Query: 326 -EARARKLRESLKTGEVTT--SQLIQQRDSLQAEVLECKQQIEKLTV-------QHKSAI 375
+ + R+L E L E T +++ + +++ + + K + + I
Sbjct: 541 NKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYPEAQEGI 600
Query: 376 QQLEEDLK--QTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN 433
+L++ LK T+ A E ++ + + + ++ + +E QA++ + K K
Sbjct: 601 MELKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 660
Query: 434 PDLPTE--REIDLWAELQATKETLRVTEDEVTTCKRE--KESENKIGIQQKLAAELLNKE 489
D+ E + + +Q T + ED ++ K + K ++Q + A+ N
Sbjct: 661 EDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSV 720
Query: 490 EIIGKMQIQT---------RELIKNIK----LNEQKVIQYEQYVRDLQAHNRTIANCQES 536
I +Q+ T E I N+K E +V++ E+ + + +A T A S
Sbjct: 721 SITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVLKLEKQLLEEKA-AMTDAMVPRS 779
Query: 537 PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREE 596
L+ E+ L KL + V E++ + + E+ Q + ++K +E+
Sbjct: 780 SYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQ 839
Query: 597 LINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+N L K + ELA +++ E ++ ++ +K+I + E+ +L L + Q
Sbjct: 840 EVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQ 895
Score = 34.7 bits (76), Expect = 1.1
Identities = 45/218 (20%), Positives = 99/218 (45%), Gaps = 12/218 (5%)
Query: 446 AELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
AE + + L+ E+ + SEN + QKL EE + K + ++ +K
Sbjct: 442 AERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSQYEEAM-KEVLSVQKQMKL 500
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANC-QESPNGISYQDLQQE-IMDLKMKLLD----- 558
++ + + Y + +L+ I Q+ N + + +E + +L+ KL++
Sbjct: 501 GLVSPESMDNYSHF-HELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGT 559
Query: 559 -VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQ 616
+ EE E+ + +E +K +E I LK+ +++ ++E +
Sbjct: 560 VIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYPEAQEGIMELKDTLKSQMTQEASDEA 619
Query: 617 QDLEHRM-RIVDEVNKQIAAKADEIQELFATLENKQQQ 653
+D++ M R++DE+NKQ++ + +E A LE+ +++
Sbjct: 620 EDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKR 657
>AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.
Length = 1583
Score = 79.8 bits (188), Expect = 3e-14
Identities = 115/499 (23%), Positives = 225/499 (45%), Gaps = 55/499 (11%)
Query: 172 LSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQD 231
L Y + L L E++++ E + + ++ +E+ L + L+ +V ++ Q
Sbjct: 732 LRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKN--ANEKTRL--ENQNLLIQVEEVSQT 787
Query: 232 VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES-------QLR 284
+ ++ + E EN K L E + EL + R + +K+ L + S ++
Sbjct: 788 CSKSEIHNEKEKCFIKEHENLKPLLEQK-ELRDRRAELILLKDSLAKSPSVKNDPLSSVK 846
Query: 285 QTRNRVAKMDKQLREAEASITSLT-GTVKMLE--DQSRQKEVQLEARARKLRESLKTGEV 341
+ ++ ++K+ +E E I + VK + D SR++ ++ LR
Sbjct: 847 ELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSA 906
Query: 342 TTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA--IQQLEEDLKQTKRALQEQCEITKRE 399
+ LIQ +S + +LE ++Q E+L V+ + A + EDL + R QCE +
Sbjct: 907 SMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSD 966
Query: 400 IE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
E L R ET LQ + +E +I+E++++K D E E +LQ ++
Sbjct: 967 NEDLLARIET-LQSNAKLLE---VQILEVQRAKAMVDKELEAE-----KLQKEQKI---- 1013
Query: 459 EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ 518
++ TT +E + ++ Q+K + + + E++ K QT L ++ YE+
Sbjct: 1014 KEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKDAQQTT-------LMNMEIADYER 1066
Query: 519 YVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELE 578
+++L N+ + N N I +DL+QEI K K E L E + ++
Sbjct: 1067 LMKEL---NQKLTN---KNNKI--EDLEQEIKIQKQK-------QETLQEEITSLQSSVQ 1111
Query: 579 Q-QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKA 637
Q ++KN++ + ++K ++EL + K ET+ A+L+ +LE + V+ Q+A
Sbjct: 1112 QYEEKNTKIKQLLVKTKKELADS-KQAETDHLILQASLKGELEASQQQVEVYKIQLAEIT 1170
Query: 638 DEIQELFATLENKQQQIHR 656
E ++ L+ +Q R
Sbjct: 1171 SEKHKIHEHLKTSAEQHQR 1189
Score = 65.3 bits (152), Expect = 7e-10
Identities = 86/420 (20%), Positives = 189/420 (45%), Gaps = 30/420 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+++++L +++ L+EM E+ E+ K + ES L + + Q E
Sbjct: 647 EQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGES-LAKINEEKCNLAFQRDE 705
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ L +K L+++S + +L++ R + ++ ++++LQ+++LE
Sbjct: 706 ---KVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLE 762
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
K EK +++++ + Q+EE + QT + + K + +KE + + + +
Sbjct: 763 MKNANEKTRLENQNLLIQVEE-VSQT--CSKSEIHNEKEKCFIKEHENLKPLLEQKELRD 819
Query: 420 LQAKIIELEKS-KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+A++I L+ S +P + + L + KE E+ CK ++E NKI
Sbjct: 820 RRAELILLKDSLAKSPSVKND-------PLSSVKELEEKIENLEKECKEKEEKINKI--- 869
Query: 479 QKLAAELLNKEEIIGKMQIQT-RELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
KL A KE + + QT +E +++++ + Q +RDL I +
Sbjct: 870 -KLVAVKAKKELDSSRKETQTVKEELESLRSEKD---QLSASMRDL------IQGAESYK 919
Query: 538 NGISYQDLQQEIMDL-KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREE 596
N + + Q E +D+ K + + HR E+L+ L + E + ++ I+ +
Sbjct: 920 NLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQS 979
Query: 597 LINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+L+ + E R A + ++LE ++ K+ A +E++EL L+ +++Q+ +
Sbjct: 980 NAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKQKKQLQK 1039
Score = 58.0 bits (134), Expect = 1e-07
Identities = 89/470 (18%), Positives = 199/470 (42%), Gaps = 32/470 (6%)
Query: 170 EHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKR--ACHERRTLIAVGEALVREVAK 227
E + + + +L LR Q E + DL R L+ V + L + AK
Sbjct: 937 ERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEV-QILEVQRAK 995
Query: 228 LRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT- 286
D E + + ++++ + LEE++ +L +++ ++L + +QT
Sbjct: 996 AMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKDAQQTT 1055
Query: 287 --RNRVAKMDKQLREAEASITSLTGTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEV 341
+A ++ ++E +T+ ++ LE + +QK+ L+ L+ S++ E
Sbjct: 1056 LMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEE 1115
Query: 342 TTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE 401
+++ Q + E+ + KQ + S +LE +Q + + EIT + +
Sbjct: 1116 KNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHK 1175
Query: 402 LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDE 461
+ E +T + + + Q ++ L++ + + +E ++ K +RV
Sbjct: 1176 IHEHLKTSAEQHQRTLSAYQQRVTALQE---ECRAAKAEQATVTSEFESYK--VRVH--- 1227
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN--EQKVIQYEQY 519
K++K + E + E +I +++I+ ++ N+++N E + +Q E
Sbjct: 1228 -NVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHD 1286
Query: 520 VRDLQAHNRTIAN--CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK--KDQ 575
L+ HN+ + +E+ +Q E M +K + V + +E+L +DQ
Sbjct: 1287 TL-LERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQ 1345
Query: 576 ELEQQDKNSRG----QARVIKIREELINVLKNKETEQSRELAALQQDLEH 621
Q+++ + Q ++ K+ +L LKN+ T +R + QQ L++
Sbjct: 1346 VRHLQEEHRKTVETLQQQLSKMEAQLFQ-LKNEPT--TRSPVSSQQSLKN 1392
Score = 57.6 bits (133), Expect = 1e-07
Identities = 84/423 (19%), Positives = 178/423 (42%), Gaps = 26/423 (6%)
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
ET+ V +E+ LRSE + A MR + + K + E +E QL + R
Sbjct: 886 ETQTVK-EELESLRSEKDQLSA--SMRDLIQGAESYKNLLLEYEKQSE-QLDVEKERANN 941
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
+ ++ + + + T + + + L AR L+ + K EV ++ + +
Sbjct: 942 FEHRIEDLTRQLRNSTLQCETINSDNED----LLARIETLQSNAKLLEVQILEVQRAKAM 997
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
+ E+ K Q E+ +H + + +LEE Q ++ ++Q + T +E+EL ++ +
Sbjct: 998 VDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKQ-KKQLQKTMQELELVKKDAQQTTL 1056
Query: 413 SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR--EKE 470
I + + + EL + N + E DL E++ K+ ++E+T+ + ++
Sbjct: 1057 MNMEIADYERLMKELNQKLTNKNNKIE---DLEQEIKIQKQKQETLQEEITSLQSSVQQY 1113
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
E I+Q L K+E+ Q +T LI L + +Q ++ + +
Sbjct: 1114 EEKNTKIKQLLVK---TKKELADSKQAETDHLILQASLKGELEASQQQ----VEVYKIQL 1166
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
A + I ++ L+ + L R L E + + EQ S ++
Sbjct: 1167 AEITSEKHKI-HEHLKTSAEQHQRTLSAYQQRVTALQEEC--RAAKAEQATVTSEFESYK 1223
Query: 591 IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
+++ ++ KNK Q+ E +Q+ EH ++D++ ++ + +Q + L+
Sbjct: 1224 VRVHN-VLKQQKNKSMSQA-ETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTL 1281
Query: 651 QQQ 653
Q +
Sbjct: 1282 QSE 1284
Score = 56.4 bits (130), Expect = 3e-07
Identities = 100/491 (20%), Positives = 211/491 (42%), Gaps = 47/491 (9%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE 248
L+ Q E+A+NT +LS++ + + V + L E+ K+R E + + + + + ++
Sbjct: 51 LQKQLEEAMNTQLELSEQLKFQNNSEDNV-KKLQEEIEKIRPGFEEQILYLQKQLDATTD 109
Query: 249 SENTKALEEMRH--ELDEERTAKL--AIKEKLTTTES-QLRQTRNRVAKMDKQLREAEAS 303
E + + ++++ E + + K +++E+L ++ + + + +++ +E EA
Sbjct: 110 -EKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAE 168
Query: 304 ITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
I L + L Q E ++ + E+L+ +Q D+ +L +
Sbjct: 169 INKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQ-----DNQICSILLQENT 223
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI----ELKERTETELQDSRNAI-- 417
+ V K ++ LE+ LK+ L+ Q I K E+ LK + E + Q ++
Sbjct: 224 FVEQVVNEK--VKHLEDTLKE----LESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFH 277
Query: 418 --EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED----EVTTCKREKES 471
E+L+ KI EL +K E+ L +EL + T + EV + K + +
Sbjct: 278 EREDLEFKINELLLAKEEQGCVIEK---LKSELAGLNKQFCYTVEQHNREVQSLKEQHQK 334
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQ-TRELIKNIKLNEQK-VIQYEQYVRDLQAHNRT 529
E I + KE++ +IQ +E +N++ +Q+ ++ YE R
Sbjct: 335 E--ISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESL--------RE 384
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEILAKKDQELEQQDKNSRGQA 588
I ++ G S + QE +K + VH ++L +KD LE ++ +G+
Sbjct: 385 IMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNR-LQGEN 443
Query: 589 RVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
+ ++EL+ L+N + L R ++ E+ +I + +E + L+
Sbjct: 444 EKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLK 503
Query: 649 NKQQQIHRLEK 659
N +++ K
Sbjct: 504 NSHEEMDNFHK 514
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 79.4 bits (187), Expect = 4e-14
Identities = 110/439 (25%), Positives = 203/439 (46%), Gaps = 45/439 (10%)
Query: 227 KLRQDVETRNVMIDEIRELRSESENTK--ALEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+L Q+V V + + E K A+ EM +L EER A+ EK E+++
Sbjct: 683 RLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAR----EK---AENRVV 735
Query: 285 QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLKTGEV 341
Q + + +D L++++ + LTG + +ED+ + +QLE + K L+ LKT
Sbjct: 736 QIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAF 795
Query: 342 TTSQLIQQRDSLQAEV---LECKQQIE----KLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
L ++ E+ LE K+ +E +LT Q++ Q+ E L+ A Q
Sbjct: 796 EADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRE-LQDQLEAEQYFST 854
Query: 395 ITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL-PTEREIDLWAELQATK 452
+ K ++ ELKE E + +++ I+ELQ E E DL T+ E + A +
Sbjct: 855 LYKTQVKELKEEIEEKNRENLKKIQELQN---EKETLATQLDLAETKAESEQLARGLLEE 911
Query: 453 ETLRVTEDEVTTCKREK-ESENKIGIQQKL--AAELLNKE-EIIGKMQIQTRELIKNIKL 508
+ +T++ R + E +K +L A +L K+ EI+ + + E +K K
Sbjct: 912 QYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMK--KA 969
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E+ ++ E+ + +L+A N + + + L EIM+ K +D R + ++
Sbjct: 970 EEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKL-AEIMNRKDFKID---RKKANTQ 1025
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK++E N + Q + + RE+ ++ + E + A L ++ HR +E
Sbjct: 1026 DLRKKEKE------NRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHR----NE 1075
Query: 629 VNKQIAAKADEIQELFATL 647
+ Q+A+K +I++L A L
Sbjct: 1076 LQMQLASKESDIEQLRAKL 1094
Score = 68.5 bits (160), Expect = 7e-11
Identities = 105/518 (20%), Positives = 215/518 (41%), Gaps = 51/518 (9%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
L E Q + +TV+ + K + + +E K R + + D++ +L
Sbjct: 467 LDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDL 526
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ S+N++ E +L ++ + + T +LR++ ++K QL +
Sbjct: 527 KKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQ 586
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ + Q+ + QL+A R L + SLQ EV K +E
Sbjct: 587 ERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLE 646
Query: 366 KLTVQHKSA----------IQQLEEDLKQTKRALQEQCE-------ITKREIELKERT-- 406
K+ + K A LE DL ++LQ++ E +TK + K ++
Sbjct: 647 KVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIE 706
Query: 407 ----------ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
E +L++ R A E+ + +++++EK D+ ++ L KE +
Sbjct: 707 EAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERM- 765
Query: 457 VTEDEV--TTCKREKESENKIGIQQKLAAELLNKEEIIG---KMQIQTRELIKNIKLNEQ 511
EDEV T + E+ES ++ +Q +L + + + G +M+ + L++ +L E
Sbjct: 766 --EDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEF 823
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGIS------YQDLQQEIMDLKMKLLDVVHRNEE 565
++ Q + R + R + + E+ S ++L++EI + + L + +
Sbjct: 824 ELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQN 883
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
E LA + +L + S AR + + E+ + + + SR + D +H +
Sbjct: 884 EKETLATQ-LDLAETKAESEQLARGL-LEEQYFELTQESKKAASRNRQEI-TDKDHTVSR 940
Query: 626 VDEVN----KQIAAKADEIQELFATLENKQQQIHRLEK 659
++E N K I E +EL ++ K ++ ++LEK
Sbjct: 941 LEEANSMLTKDIEILRRENEELTEKMK-KAEEEYKLEK 977
Score = 48.4 bits (110), Expect = 9e-05
Identities = 62/279 (22%), Positives = 125/279 (44%), Gaps = 21/279 (7%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAV-GEALVREVAKLRQDVETRNVMIDEI 242
G +REL+ Q E A + L K E + I ++++ +L+ + ET +D +
Sbjct: 837 GQMRELQDQLE-AEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLD-L 894
Query: 243 RELRSESENTKA--LEEMRHELDEE-RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
E ++ESE LEE EL +E + A ++++T + + + + + K +
Sbjct: 895 AETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEI 954
Query: 300 AEASITSLTGTVKMLEDQ---SRQKEVQ-LEARARK---LRESLKTGEVTTSQLIQQRDS 352
LT +K E++ +++E+ L+A K +LKT V I R
Sbjct: 955 LRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKD 1014
Query: 353 LQAEVLECK-QQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEITKREIELKE----RT 406
+ + + Q + K +++ +L ++ ++ + ++ Q E+ + +L E R
Sbjct: 1015 FKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRN 1074
Query: 407 ETELQ--DSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
E ++Q + IE+L+AK+++L S P+ E D
Sbjct: 1075 ELQMQLASKESDIEQLRAKLLDLSDSTSVASFPSADETD 1113
Score = 44.8 bits (101), Expect = 0.001
Identities = 73/395 (18%), Positives = 166/395 (42%), Gaps = 35/395 (8%)
Query: 268 AKLAIKEKLTTTESQLR-QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLE 326
A +++E L T +L Q N + D+ ++ S L +K L+++ Q+ LE
Sbjct: 420 ADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR-NLE 478
Query: 327 ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK 386
+ ++ + L+Q R + E + + + S ++ EDLK+
Sbjct: 479 STVSQIEKE--------KMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKV- 529
Query: 387 RALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
+ ++ ++ + + +L+++ + + + L KS + L
Sbjct: 530 ---SQNSQLANEKL---SQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNR 583
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQ---TRELI 503
ELQ E R+ E+ + + +K+ I + + + E+IG +Q + +E +
Sbjct: 584 ELQ---ERNRILEN--SKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEV 638
Query: 504 KNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRN 563
K++K N +KV + +D+ H+ ++ N + DL ++ L+ +L V+ +
Sbjct: 639 KHLKHNLEKVEGERKEAQDMLNHS------EKEKNNLEI-DLNYKLKSLQQRLEQEVNEH 691
Query: 564 EELSEILAKKDQELEQQDKNSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
+ L K Q +E+ + + + +K E +N+ + ++ + L DL+
Sbjct: 692 KVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQS 751
Query: 623 MRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
+ ++ + DE++ L TL+ +Q+ RL
Sbjct: 752 QQKLEHLTGNKERMEDEVKNL--TLQLEQESNKRL 784
Score = 35.9 bits (79), Expect = 0.49
Identities = 55/288 (19%), Positives = 128/288 (44%), Gaps = 24/288 (8%)
Query: 373 SAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKP 432
+A + L+E L++T L+EQ E++LK+ E + + S ++++ ++ E +
Sbjct: 419 NADKSLQESLQKTIYKLEEQLH---NEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR 475
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEII 492
N + ++++ K L+ +E K E+E+E + ++ +++ K+++
Sbjct: 476 NLESTV-------SQIEKEKMLLQHRINEYQR-KAEQENEKRRNVENEVSTL---KDQLE 524
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
++ + N KL++ + Q E+ L+ + T ++S + ++ + I L
Sbjct: 525 DLKKVSQNSQLANEKLSQLQK-QLEEANDLLRTESDTAVRLRKS-----HTEMSKSISQL 578
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSREL 612
+ ++ RN L ++ D++ Q + R E+I L+ + T E+
Sbjct: 579 ESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEV 638
Query: 613 AALQQDLE----HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
L+ +LE R D +N K + +L L++ QQ++ +
Sbjct: 639 KHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQ 686
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 79.4 bits (187), Expect = 4e-14
Identities = 117/577 (20%), Positives = 251/577 (43%), Gaps = 37/577 (6%)
Query: 103 LPQELILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQD 162
+ +E++L + + +L D IA E + +L +E +N+ K + Q+
Sbjct: 983 MEEEILLLEDQNSKFIKEKKLMEDRIA----ECSSQLAEEEEKAKNLAK-----IRNKQE 1033
Query: 163 QTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV 222
D+ E L + EL A R+L + D + + +L + + L E L
Sbjct: 1034 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093
Query: 223 REVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
+A+ + +N + +REL+++ +E + E + ++ K + E+L ++
Sbjct: 1094 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT 1153
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEV 341
+L T + A + + E + L K LE++++ E Q++ +R+ T
Sbjct: 1154 ELEDTLDTTAAQQELRTKREQEVAELK---KALEEETKNHEAQIQ----DMRQRHATALE 1206
Query: 342 TTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
S+ ++Q +A + + KQ +E K +QQ++ + + ++ L Q +
Sbjct: 1207 ELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA 1266
Query: 399 EIELKERTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ +R EL + + ++ EL LE+++ + L ++LQ T+E L+
Sbjct: 1267 KVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQE 1326
Query: 458 -TEDEVTTCKREK---ESENKIGIQQKLAAELL-NKEEIIGKMQIQTRELIKNIKLNEQK 512
T ++ R + E +N + QQ+ E N E+ + +Q Q + K + +
Sbjct: 1327 ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT 1386
Query: 513 VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK----LLDVVHRNEELSE 568
+ E+ + L ++ E ++Y L++ L+ + +D+ H+ + S
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLEE-KALAYDKLEKTKNRLQQEPDDLTVDLDHQRQVASN 1445
Query: 569 ILAKKDQELEQQDKNSRG-QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
L KK ++ +Q + AR + R+ + KET+ AL++ LE + +
Sbjct: 1446 -LEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF-E 1503
Query: 628 EVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
NKQ+ A ++++L ++ ++ + +H LEK AL
Sbjct: 1504 RQNKQLRA---DMEDLMSSKDDVGKNVHELEKSKRAL 1537
Score = 70.5 bits (165), Expect = 2e-11
Identities = 106/517 (20%), Positives = 221/517 (42%), Gaps = 46/517 (8%)
Query: 172 LSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQD 231
L +G + L++Q +D + + +++ + + + E + ++
Sbjct: 1296 LEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEE 1355
Query: 232 VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
E R + ++ L+S+ +TK +++ +L + + A K+ L E+ ++ +
Sbjct: 1356 EEARKNLEKQVLALQSQLADTK--KKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKAL 1413
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
DK L + + + + + D RQ LE + +K + L + +++ ++RD
Sbjct: 1414 AYDK-LEKTKNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD 1472
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITK-------REIEL 402
+AE E + + L + A++ EE +Q K RA E +K E+E
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532
Query: 403 KERT-ETELQDSRNAIEELQAKIIELEKSKPNPD-----LPTEREIDLWAELQATKETLR 456
+R E ++++ R +EEL+ ++ E +K + + + E DL + +E R
Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592
Query: 457 VTEDEVTTCKREKESENK-----IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQ 511
+ +V + E E E K + ++K+ +L + E I E+IK ++ +
Sbjct: 1593 LLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQA 1652
Query: 512 KVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQEIMDLKMKLLD--------VVHR 562
++ Y++ + + +A + A +ES + + L+ EI+ L+ +L R
Sbjct: 1653 QMKDYQRELEEARASRDEIFAQSKESEKKL--KSLEAEILQLQEELASSERARRHAEQER 1710
Query: 563 NEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
+E EI + D+ R +AR+ ++ EEL E EQS + L
Sbjct: 1711 DELADEITNSASGKSALLDEKRRLEARIAQLEEEL-------EEEQS-NMELLNDRFRKT 1762
Query: 623 MRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
VD +N ++AA+ Q+ +N +QQ+ R K
Sbjct: 1763 TLQVDTLNAELAAERSAAQK----SDNARQQLERQNK 1795
Score = 67.7 bits (158), Expect = 1e-10
Identities = 100/454 (22%), Positives = 199/454 (43%), Gaps = 31/454 (6%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L E K++ ++ +DE R + + K E + + EE L +
Sbjct: 939 QILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFI 998
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL---EARARKLRES 335
E +L + +R+A+ QL E E +L E E +L E ++L ++
Sbjct: 999 KEKKLME--DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1056
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
+ + T+ L Q LQA++ E K Q+ K + + A+ + +++ AL+ E+
Sbjct: 1057 KRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVREL 1116
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ EL+E E+E + SRN E+ + + E ++ L TE E L + A ++ L
Sbjct: 1117 QAQIAELQEDFESE-KASRNKAEKQKRDLSEELEA-----LKTELEDTL--DTTAAQQEL 1168
Query: 456 RV-TEDEVTTCKREKESENK---IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQ 511
R E EV K+ E E K IQ EE+ +++ Q + N++ N+Q
Sbjct: 1169 RTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE-QAKRFKANLEKNKQ 1227
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILA 571
+ E ++L + + ++ + + L ++ +L K+ + EL+E +
Sbjct: 1228 GL---ETDNKELACEVKVLQQV-KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKAS 1283
Query: 572 KKDQELEQ-QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVN 630
K EL+ + + IK ++ ++ + + ++EL LQ++ ++ + +
Sbjct: 1284 KLQNELDNVSTLLEEAEKKGIKFAKDAASL--ESQLQDTQEL--LQEETRQKLNLSSRI- 1338
Query: 631 KQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
+Q+ + + +QE E +++ LEK VLAL
Sbjct: 1339 RQLEEEKNSLQE---QQEEEEEARKNLEKQVLAL 1369
Score = 67.3 bits (157), Expect = 2e-10
Identities = 83/413 (20%), Positives = 180/413 (43%), Gaps = 27/413 (6%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQ---LREAEASITSLTGTVKMLEDQ 317
EL + L +KEK T E +L + + ++ ++ L E + T L + + +
Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRAR 912
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
K+ +LE L ++ E L ++ +QA + + ++Q+++ + Q
Sbjct: 913 LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKL--Q 970
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
LE+ + K E+ + + K E +L + R I E +++ E E+ N
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR--IAECSSQLAEEEEKAKNLAKI 1028
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
++ + ++L+ + T E+ KR+ + E +Q ++A +E+ ++
Sbjct: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET-TDLQDQIAELQAQIDELKLQLAK 1087
Query: 498 QTRELIKNIKLNEQKVIQYE---QYVRDLQAHNRTIANCQESPNGI------SYQDLQQE 548
+ EL + + + + + VR+LQA + ES +DL +E
Sbjct: 1088 KEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEE 1147
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQE-------LEQQDKNSRGQARVIKIREELINVL 601
+ LK +L D + E+ K++QE LE++ KN Q + ++ R
Sbjct: 1148 LEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEE 1207
Query: 602 KNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+++ EQ++ A +LE + ++ NK++A + +Q++ A E+K++++
Sbjct: 1208 LSEQLEQAKRFKA---NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL 1257
Score = 56.4 bits (130), Expect = 3e-07
Identities = 94/492 (19%), Positives = 202/492 (41%), Gaps = 36/492 (7%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR 243
G + L+ + + LS+R E + L + L + +L+Q+ + V +D R
Sbjct: 1385 GTIESLEEAKKKLLKDAEALSQRL--EEKALAY--DKLEKTKNRLQQEPDDLTVDLDHQR 1440
Query: 244 ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEAS 303
++ S E K ++ L EE++ E+ E++ R+ + + + L EA +
Sbjct: 1441 QVASNLE--KKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 304 ITSLTGTVKML----EDQSRQKEV------QLEARARKLRESLKTGEVTTSQLIQQRDSL 353
K L ED K+ +LE R L + ++ +L + +
Sbjct: 1499 KEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ L + ++ + Q + +Q +E ++ KR L +Q + E+E + + S
Sbjct: 1559 EDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVAS 1618
Query: 414 RNAIE----ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREK 469
+ +E +L+A+I K++ + + Q E R + DE+ + K
Sbjct: 1619 KKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFA--QSK 1676
Query: 470 ESENKIGIQQKLAAELLN-KEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNR 528
ESE K+ + L AE+L +EE+ + + + +L ++ L R
Sbjct: 1677 ESEKKL---KSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRR 1733
Query: 529 TIANCQESPNGISYQDLQQEIMDLKMK--LLDVVHRNEELS---EILAKKD---QELEQQ 580
A + + + E+++ + + L V N EL+ K D Q+LE+Q
Sbjct: 1734 LEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQ 1793
Query: 581 DKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI 640
+K + A++ ++ + + K + ++ L++ LE + NK + ++
Sbjct: 1794 NKELK--AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKL 1851
Query: 641 QELFATLENKQQ 652
+E+F +E++++
Sbjct: 1852 KEIFMQVEDERR 1863
Score = 51.2 bits (117), Expect = 1e-05
Identities = 41/191 (21%), Positives = 89/191 (46%), Gaps = 7/191 (3%)
Query: 242 IRELRSESENTKALEEMRHELDEERTAKL-AIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
I +L E E ++ E+ ++ + T ++ + +L S +++ N ++++Q +E
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1797
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDSLQAEV 357
+A + L G VK + + LEA+ +L E L+ ++L+++ + E+
Sbjct: 1798 KAKLQELEGAVK---SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEI 1854
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ + Q+K +++ +KQ KR L+E E R + + + EL D+ A
Sbjct: 1855 FMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEAN 1914
Query: 418 EELQAKIIELE 428
E L ++ L+
Sbjct: 1915 EGLSREVSTLK 1925
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/210 (23%), Positives = 103/210 (49%), Gaps = 21/210 (10%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
+E K + +E + + E EL S + E+ R EL +E T + K L +
Sbjct: 1676 KESEKKLKSLEAEILQLQE--ELASSERARRHAEQERDELADEITNSASGKSALL---DE 1730
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTG 339
R+ R+A+++++L E ++++ ++L D+ R+ +Q++ +L R + +
Sbjct: 1731 KRRLEARIAQLEEELEEEQSNM-------ELLNDRFRKTTLQVDTLNAELAAERSAAQKS 1783
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
+ QL +Q L+A++ E + ++ K T+ A I QLEE L+Q + ++
Sbjct: 1784 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL 1843
Query: 396 TKR-EIELKERTETELQDSRNAIEELQAKI 424
+R E +LKE +++D R ++ + ++
Sbjct: 1844 VRRTEKKLKE-IFMQVEDERRHADQYKEQM 1872
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase 1 protein.
Length = 1354
Score = 79.4 bits (187), Expect = 4e-14
Identities = 110/439 (25%), Positives = 203/439 (46%), Gaps = 45/439 (10%)
Query: 227 KLRQDVETRNVMIDEIRELRSESENTK--ALEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+L Q+V V + + E K A+ EM +L EER A+ EK E+++
Sbjct: 683 RLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAR----EK---AENRVV 735
Query: 285 QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLKTGEV 341
Q + + +D L++++ + LTG + +ED+ + +QLE + K L+ LKT
Sbjct: 736 QIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAF 795
Query: 342 TTSQLIQQRDSLQAEV---LECKQQIE----KLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
L ++ E+ LE K+ +E +LT Q++ Q+ E L+ A Q
Sbjct: 796 EADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRE-LQDQLEAEQYFST 854
Query: 395 ITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL-PTEREIDLWAELQATK 452
+ K ++ ELKE E + +++ I+ELQ E E DL T+ E + A +
Sbjct: 855 LYKTQVKELKEEIEEKNRENLKKIQELQN---EKETLATQLDLAETKAESEQLARGLLEE 911
Query: 453 ETLRVTEDEVTTCKREK-ESENKIGIQQKL--AAELLNKE-EIIGKMQIQTRELIKNIKL 508
+ +T++ R + E +K +L A +L K+ EI+ + + E +K K
Sbjct: 912 QYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTERMK--KA 969
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E+ ++ E+ + +L+A N + + + L EIM+ K +D R + ++
Sbjct: 970 EEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKL-AEIMNRKDFKID---RKKANTQ 1025
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L KK++E N + Q + + RE+ ++ + E + A L ++ HR +E
Sbjct: 1026 DLRKKEKE------NRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHR----NE 1075
Query: 629 VNKQIAAKADEIQELFATL 647
+ Q+A+K +I++L A L
Sbjct: 1076 LQMQLASKESDIEQLRAKL 1094
Score = 66.5 bits (155), Expect = 3e-10
Identities = 104/518 (20%), Positives = 215/518 (41%), Gaps = 51/518 (9%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
L E Q + +TV+ + K + + +E K R + + +++ +L
Sbjct: 467 LDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKNQLEDL 526
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ S+N++ E +L ++ + + T +LR++ ++K QL +
Sbjct: 527 KKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQ 586
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ + Q+ + QL+A R L + SLQ EV K +E
Sbjct: 587 ERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLE 646
Query: 366 KLTVQHKSA----------IQQLEEDLKQTKRALQEQCE-------ITKREIELKERT-- 406
K+ + K A LE DL ++LQ++ E +TK + K ++
Sbjct: 647 KVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIE 706
Query: 407 ----------ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
E +L++ R A E+ + +++++EK D+ ++ L KE +
Sbjct: 707 EAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERM- 765
Query: 457 VTEDEV--TTCKREKESENKIGIQQKLAAELLNKEEIIG---KMQIQTRELIKNIKLNEQ 511
EDEV T + E+ES ++ +Q +L + + + G +M+ + L++ +L E
Sbjct: 766 --EDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEF 823
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGIS------YQDLQQEIMDLKMKLLDVVHRNEE 565
++ Q + R + R + + E+ S ++L++EI + + L + +
Sbjct: 824 ELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQN 883
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
E LA + +L + S AR + + E+ + + + SR + D +H +
Sbjct: 884 EKETLATQ-LDLAETKAESEQLARGL-LEEQYFELTQESKKAASRNRQEI-TDKDHTVSR 940
Query: 626 VDEVN----KQIAAKADEIQELFATLENKQQQIHRLEK 659
++E N K I E +EL ++ K ++ ++LEK
Sbjct: 941 LEEANSMLTKDIEILRRENEELTERMK-KAEEEYKLEK 977
Score = 48.4 bits (110), Expect = 9e-05
Identities = 62/279 (22%), Positives = 125/279 (44%), Gaps = 21/279 (7%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAV-GEALVREVAKLRQDVETRNVMIDEI 242
G +REL+ Q E A + L K E + I ++++ +L+ + ET +D +
Sbjct: 837 GQMRELQDQLE-AEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLD-L 894
Query: 243 RELRSESENTKA--LEEMRHELDEE-RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
E ++ESE LEE EL +E + A ++++T + + + + + K +
Sbjct: 895 AETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEI 954
Query: 300 AEASITSLTGTVKMLEDQ---SRQKEVQ-LEARARK---LRESLKTGEVTTSQLIQQRDS 352
LT +K E++ +++E+ L+A K +LKT V I R
Sbjct: 955 LRRENEELTERMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKD 1014
Query: 353 LQAEVLECK-QQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEITKREIELKE----RT 406
+ + + Q + K +++ +L ++ ++ + ++ Q E+ + +L E R
Sbjct: 1015 FKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRN 1074
Query: 407 ETELQ--DSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
E ++Q + IE+L+AK+++L S P+ E D
Sbjct: 1075 ELQMQLASKESDIEQLRAKLLDLSDSTSVASFPSADETD 1113
Score = 44.8 bits (101), Expect = 0.001
Identities = 73/395 (18%), Positives = 166/395 (42%), Gaps = 35/395 (8%)
Query: 268 AKLAIKEKLTTTESQLR-QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLE 326
A +++E L T +L Q N + D+ ++ S L +K L+++ Q+ LE
Sbjct: 420 ADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR-NLE 478
Query: 327 ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK 386
+ ++ + L+Q R + E + + + S ++ EDLK+
Sbjct: 479 STVSQIEKE--------KMLLQHRINEYQRKAEQENEKRRNVENEVSTLKNQLEDLKKV- 529
Query: 387 RALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
+ ++ ++ + + +L+++ + + + L KS + L
Sbjct: 530 ---SQNSQLANEKL---SQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNR 583
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQ---TRELI 503
ELQ E R+ E+ + + +K+ I + + + E+IG +Q + +E +
Sbjct: 584 ELQ---ERNRILEN--SKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEV 638
Query: 504 KNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRN 563
K++K N +KV + +D+ H+ ++ N + DL ++ L+ +L V+ +
Sbjct: 639 KHLKHNLEKVEGERKEAQDMLNHS------EKEKNNLEI-DLNYKLKSLQQRLEQEVNEH 691
Query: 564 EELSEILAKKDQELEQQDKNSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
+ L K Q +E+ + + + +K E +N+ + ++ + L DL+
Sbjct: 692 KVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQS 751
Query: 623 MRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
+ ++ + DE++ L TL+ +Q+ RL
Sbjct: 752 QQKLEHLTGNKERMEDEVKNL--TLQLEQESNKRL 784
Score = 37.1 bits (82), Expect = 0.21
Identities = 57/288 (19%), Positives = 129/288 (44%), Gaps = 24/288 (8%)
Query: 373 SAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKP 432
+A + L+E L++T L+EQ E++LK+ E + + S ++++ ++ E +
Sbjct: 419 NADKSLQESLQKTIYKLEEQLH---NEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR 475
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEII 492
N + ++++ K L+ +E K E+E+E + ++ +++ L N+ E +
Sbjct: 476 NLESTV-------SQIEKEKMLLQHRINEYQR-KAEQENEKRRNVENEVST-LKNQLEDL 526
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
K+ +N +L +K+ Q ++ + + RT ++ S+ ++ + I L
Sbjct: 527 KKVS-------QNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRK-SHTEMSKSISQL 578
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSREL 612
+ ++ RN L ++ D++ Q + R E+I L+ + T E+
Sbjct: 579 ESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEV 638
Query: 613 AALQQDLE----HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
L+ +LE R D +N K + +L L++ QQ++ +
Sbjct: 639 KHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQ 686
>AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein.
Length = 1571
Score = 79.4 bits (187), Expect = 4e-14
Identities = 115/479 (24%), Positives = 200/479 (41%), Gaps = 43/479 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID-EIRE 244
L E +QA + V L+K T IA E +R+ K RQ++E +D E E
Sbjct: 601 LAEFSSQAAEEEEKVKSLNKLRLKYEAT-IADMEDRLRKEEKGRQELEKLKRRLDGESSE 659
Query: 245 LRSES-ENTKALEEMRHEL---DEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
L+ + E + EE+R +L +EE A LA E +QL ++ + + L EA
Sbjct: 660 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS---LREAQAALAEA 716
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
+ + S E Q R +LEA +L ++L + T+ + R + EV E
Sbjct: 717 QEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDS----TNAQQELRSKREQEVTEL 772
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
K+ +E+ T H++A+Q+L + Q L EQ E +R E+T L+ + EL
Sbjct: 773 KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE---VSEL 829
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+A++ L+ ++ + R ELQ + R + E + E+ K+ Q+
Sbjct: 830 RAELSSLQTARQEGEQRRRR-----LELQLQEVQGRAGDGE----RARAEAAEKL---QR 877
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGI 540
AEL N + + + +T L K + E ++ ++ LQ R + G
Sbjct: 878 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL---LQEETRA-----KLALGS 929
Query: 541 SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINV 600
+ ++ E L+ +L + E L +L + + +A ++ EE
Sbjct: 930 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEE---- 985
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+RE AL Q L + VD + + E+ + LE ++Q + LEK
Sbjct: 986 ---ARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEK 1041
Score = 77.0 bits (181), Expect = 2e-13
Identities = 106/518 (20%), Positives = 212/518 (40%), Gaps = 28/518 (5%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L + + T D+ + L + EL R L ++ + + + +RA R L
Sbjct: 621 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR 680
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAKLAIKEK 275
E L +A+ + R ++ +RE ++ +E + LE R + + + E+
Sbjct: 681 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 740
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL-EARAR---- 330
L +L T + + + E +T L K LE+++R E + E R R
Sbjct: 741 LEALRGELEDTLDSTNAQQELRSKREQEVTELK---KTLEEETRIHEAAVQELRQRHGQA 797
Query: 331 --KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQT 385
+L E L+ + R +L+AEV E + ++ L + Q+ LE L++
Sbjct: 798 LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEV 857
Query: 386 KRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLW 445
+ + E +R + EL++ A+ E ++K I L K + + +L
Sbjct: 858 QGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL 917
Query: 446 AELQATKETL--RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELI 503
E K L RV E ++ E + +++ EL + + + + + E
Sbjct: 918 QEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA 977
Query: 504 KNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVH 561
++ E+ + R+ +A + +A E+ + + + LQQE+ D M L
Sbjct: 978 GALEAGEEA---RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL----E 1030
Query: 562 RNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEH 621
+ +L L KK ++ +Q + A V++ EE ++R L+ L + LE
Sbjct: 1031 QQRQLVSTLEKKQRKFDQLLAEEK--AAVLRAVEERERAEAEGREREARALS-LTRALEE 1087
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+E+ +Q A E++ L ++ ++ + +H LE+
Sbjct: 1088 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELER 1125
Score = 69.3 bits (162), Expect = 4e-11
Identities = 116/507 (22%), Positives = 215/507 (42%), Gaps = 48/507 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS 247
+L + + AV + +RA E R A +L R L ++ E R + + R LR+
Sbjct: 1048 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA---LEEEQEAREELERQNRALRA 1104
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
E LE + D+ + ++ E R +V +++ +L AE + L
Sbjct: 1105 E------LEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRL 1158
Query: 308 TGTVKMLEDQSRQ----KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
TV+ L+ Q + ++ E R R+L + L+ EV + +QR A + + +
Sbjct: 1159 EVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGE 1218
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
+E+L Q SA Q EE +KQ R +Q Q + RE+E + RT E S+N E + K
Sbjct: 1219 LEELKAQMASAGQGKEEAVKQL-RKMQAQMKELWREVE-ETRTSREEIFSQNRESEKRLK 1276
Query: 424 IIELEKSKPNPDLPTEREIDLWAEL---QATKETLRVTEDEVTTCKREKESENKIG-IQQ 479
+E E + +L A+ + E + + +++ E ++G +++
Sbjct: 1277 GLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEE 1336
Query: 480 KLAAELLNKE---EIIGKMQIQTRELIKNIKLN-------EQKVIQYEQYVRDLQA---- 525
+L E N E + K+ +Q L + E Q E+ +++L+
Sbjct: 1337 ELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGE 1396
Query: 526 --------HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL 577
H TIA ES + + L+QE + + V + L E++ + ++E
Sbjct: 1397 EDAGARARHKMTIA-ALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1455
Query: 578 EQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAA---LQQDLEHRMRIVDEVNKQI 633
D+ R Q +R ++L L+ E E SR A LQ++LE + +N+++
Sbjct: 1456 RVADQ-LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREV 1514
Query: 634 AAKADEIQELFATLENKQ-QQIHRLEK 659
+ ++ T + +Q+ RLE+
Sbjct: 1515 TTLRNRLRRGPLTFTTRTVRQVFRLEE 1541
Score = 62.1 bits (144), Expect = 6e-09
Identities = 69/314 (21%), Positives = 138/314 (43%), Gaps = 17/314 (5%)
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
+++Q R +V E +QQ + + + + QLEE+ + L+ + E+ E +
Sbjct: 445 EVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRG 504
Query: 405 RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET-----LRVTE 459
R Q+ + EL+A++ E E+ +R EL+A E ++
Sbjct: 505 RLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQL 564
Query: 460 DEVTT-CKREKESENKIGIQ---QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQ 515
++VTT K +K E+ + ++ KL+ E E+ + + Q E + +K + ++
Sbjct: 565 EKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLK 624
Query: 516 YEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQ 575
YE + D++ R ++ + + L E +L+ ++++ R EEL L +K++
Sbjct: 625 YEATIADMEDRLRKEEKGRQELEKLK-RRLDGESSELQEQMVEQQQRAEELRAQLGRKEE 683
Query: 576 ELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAA 635
EL+ + + R +L+ L+ E LA Q+DLE + KQ
Sbjct: 684 ELQAALARAEDEGGA---RAQLLKSLR----EAQAALAEAQEDLESERVARTKAEKQRRD 736
Query: 636 KADEIQELFATLEN 649
+E++ L LE+
Sbjct: 737 LGEELEALRGELED 750
Score = 60.5 bits (140), Expect = 2e-08
Identities = 94/436 (21%), Positives = 182/436 (41%), Gaps = 36/436 (8%)
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
LR N A ++RH K+ ++T + L+ + K+ + +++ +
Sbjct: 409 LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV 468
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT-GEVTTSQ-----LIQQRDSLQAEVL 358
L G V LE++ + QL A A E+ +T G + + ++ + ++ E
Sbjct: 469 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE 528
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE-QCEITKREIELKERTE----TELQDS 413
EC +Q++ + + IQ+LE L+ + A Q+ Q E E ++K+ E E Q+S
Sbjct: 529 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 588
Query: 414 RNAIEE--LQAKIIELEKSKPNPDLPTEREIDLWAELQAT----KETLRVTE---DEVTT 464
+ + E L+ ++ E + + L + +AT ++ LR E E+
Sbjct: 589 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 648
Query: 465 CKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQ 524
KR + E+ +Q+++ + EE+ ++ + EL + E + Q ++ L+
Sbjct: 649 LKRRLDGESS-ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLR 707
Query: 525 AHNRTIANCQESPNG---------ISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQ 575
+A QE +DL +E+ L+ +L D + E+ +K++Q
Sbjct: 708 EAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQ 767
Query: 576 ELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAA 635
E+ + K + R I E + L+ + + ELA + LE R K A
Sbjct: 768 EVTELKKTLEEETR---IHEAAVQELRQRHGQALGELA---EQLEQARRGKGAWEKTRLA 821
Query: 636 KADEIQELFATLENKQ 651
E+ EL A L + Q
Sbjct: 822 LEAEVSELRAELSSLQ 837
Score = 53.6 bits (123), Expect = 2e-06
Identities = 104/475 (21%), Positives = 203/475 (42%), Gaps = 49/475 (10%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E L+ + + E+ + + + + L + EA + + +L Q+ ETR +
Sbjct: 870 EAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST-EAQLHDAQELLQE-ETRAKLAL 927
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
R E+E +R +L+EE A+ +L T ++QL + R R +E
Sbjct: 928 GSRVRAMEAEAAG----LREQLEEEAAARERAGRELQTAQAQLSEWRRR--------QEE 975
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDSLQAEV 357
EA G ++ E+ R+ + EA ++L E +T E +L Q+ D ++
Sbjct: 976 EA------GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1029
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ +Q + L + + Q L E+ RA++E+ + E E +ER L +R A+
Sbjct: 1030 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER---ERAEAEGREREARALSLTR-AL 1085
Query: 418 EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
EE Q ELE+ N L E E A L + + + + C+ +++ N +
Sbjct: 1086 EEEQEAREELERQ--NRALRAELE----ALLSSKDDVGKSVHELERACRVAEQAANDLRA 1139
Query: 478 Q-QKLAAELLNKEEIIGKMQI--------QTRELIKNIKLNEQKVIQYEQYVRDLQAHNR 528
Q +L EL E+ ++++ R+L + E++ Q + +RD + R
Sbjct: 1140 QVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV-ER 1198
Query: 529 TIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQA 588
Q + + + L+ E+ +LK ++ EE + L K ++++ + +
Sbjct: 1199 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE-ET 1257
Query: 589 RVIKIREELINVLKNKETEQS-RELAALQQDLEHRMRIVDEVNKQIAAKADEIQE 642
R REE+ + +N+E+E+ + L A L+ + D +Q DE+ +
Sbjct: 1258 RT--SREEIFS--QNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD 1308
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 79.0 bits (186), Expect = 5e-14
Identities = 101/474 (21%), Positives = 218/474 (45%), Gaps = 38/474 (8%)
Query: 205 KRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDE 264
K ER L + EAL + +L++ + I E + + +S N K E D
Sbjct: 1325 KSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMK-------EKDN 1377
Query: 265 ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQ 324
E T ++ E+ +S L + + + K+L+E+ + S+ K +D R +EV
Sbjct: 1378 ETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVA---KEKDDLQRLQEV- 1433
Query: 325 LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ 384
L++ + +L+E++K E+ L + + A C ++ E+ + + + + E ++
Sbjct: 1434 LQSESDQLKENIK--EIVAKHLETEEELKVAHC--CLKEQEETINELRVNLSEKETEIST 1489
Query: 385 TKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL 444
++ L+ + K + +++E E E Q + I E+Q K+ EL++ K + +
Sbjct: 1490 IQKQLEAIND--KLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSI 1547
Query: 445 WAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELL--NKEEIIGKM---QIQT 499
+++ L+ +++E+ +EKE ++ ++ + L N +EI+ KM Q +
Sbjct: 1548 ESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKE 1607
Query: 500 RELIKNIKLNE--QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM--K 555
+ +K +NE +K+ + E + + N E+ N Q L + + +++ K
Sbjct: 1608 YQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENI-ETENIRLTQILHENLEEMRSVTK 1666
Query: 556 LLDVVHRNEELSEI----LAKKDQELEQQDKNSRGQARVI----KIREELINVLKNKETE 607
D + EE ++ L + +E +D + + +++ K +E I+ L+ +E
Sbjct: 1667 ERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSE 1726
Query: 608 QSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIV 661
++ E++ +Q+DLEH D + Q +E++ L+ +Q+ I +L IV
Sbjct: 1727 KTNEISNMQKDLEHSN---DALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIV 1777
Score = 78.2 bits (184), Expect = 9e-14
Identities = 118/499 (23%), Positives = 227/499 (45%), Gaps = 55/499 (11%)
Query: 182 LCGALRELK-TQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
LC E K T + +N + A E L++ ++L EV +LR++++ ++ +
Sbjct: 693 LCNLELEGKITDLQKELNKEVE-ENEALREEVILLSELKSLPSEVERLRKEIQDKS---E 748
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ + SE + K E+ H+ E R L E++ T+ L T++ D++ +
Sbjct: 749 ELHIITSEKD--KLFSEVVHK--ESRVQGLL--EEIGKTKDDLATTQSNYKSTDQEFQNF 802
Query: 301 EASITSLTGTVKM-LEDQSR--QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ KM LE+ R Q+ V L A+K SL G + T +L + LQ +
Sbjct: 803 KTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSL--GALKT-ELSYKTQELQEKT 859
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E ++++ ++ Q K ++ + L+ +R E+ IT++ + E +T Q+ ++ +
Sbjct: 860 REVQERLNEME-QLKEQLENRDSTLQTVER---EKTLITEKLQQTLEEVKTLTQE-KDDL 914
Query: 418 EELQAKI-IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK---------- 466
++LQ + IE ++ K + ID +L+ E+L+ ++ + T K
Sbjct: 915 KQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRN 974
Query: 467 ---REKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
E E K QQK+ + K+++ K T+ L ++K NE +I+ ++ + L
Sbjct: 975 LHMEENTGETKDEFQQKMVG-IDKKQDLEAK---NTQTLTADVKDNE--IIEQQRKIFSL 1028
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI--LAKKDQELEQQD 581
+ ES + +Q DLK + + EEL + KK QE+ Q+
Sbjct: 1029 IQEKNELQQMLESV----IAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQE 1084
Query: 582 KNS--RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
KN + + + + + L V + K E+S++L QQ L + + E+ K+I +E
Sbjct: 1085 KNHAIKKEGELSRTCDRLAEV-EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKI----NE 1139
Query: 640 IQELFATLENKQQQIHRLE 658
I+ L L+NK+ + +E
Sbjct: 1140 IENLKNELKNKELTLEHME 1158
Score = 70.5 bits (165), Expect = 2e-11
Identities = 101/481 (20%), Positives = 209/481 (43%), Gaps = 37/481 (7%)
Query: 196 AVNTVTDLSKRACHER----RTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESEN 251
++N + ++ + C E TL + E KL + N+ E+ LR++ +N
Sbjct: 459 SINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKL---LNQENIE-SELNSLRADYDN 514
Query: 252 TKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTR----NRVAKMDKQLREAEASITS 306
E++R E EE KL K L E+ R+T+ N ++ + LRE E I
Sbjct: 515 LVLDYEQLRTE-KEEMELKLKEKNDLDEFEALERKTKKDQENELSSKVELLREKEDQIKK 573
Query: 307 LTGTV--KMLEDQSRQKEVQLEA--RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
L + + LE+ LE+ ++++++L E ++ L++E LE K+
Sbjct: 574 LQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKE 633
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
++++L +K Q+E D++ + L+ + K +++L E ELQ + N I +L +
Sbjct: 634 KMKELATTYK----QMENDIQLYQSQLEAK---KKMQVDL----EKELQSAFNEITKLTS 682
Query: 423 KIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
I +L E +I DL EL E +EV K +++ ++L
Sbjct: 683 LIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEV---ERL 739
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
E+ +K E + + + +L + E +V + + + T + +S +
Sbjct: 740 RKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQ-E 798
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVL 601
+Q+ + MD + K V+ NE +++ + +E ++ D + + + + +
Sbjct: 799 FQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEK 858
Query: 602 KNKETEQSRELAALQQDLEHR---MRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ E+ E+ L++ LE+R ++ V+ I K + E TL ++ + +L+
Sbjct: 859 TREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQ 918
Query: 659 K 659
+
Sbjct: 919 E 919
Score = 65.3 bits (152), Expect = 7e-10
Identities = 87/444 (19%), Positives = 198/444 (44%), Gaps = 27/444 (6%)
Query: 212 RTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAKL 270
+ ++ E + +E+ L ++ + + + L++E S T+ L+E E+ E
Sbjct: 814 KMVLEENERMNQEIVNLSKEAQKFD---SSLGALKTELSYKTQELQEKTREVQERLNEME 870
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
+KE+L +S L+ + ++L++ + +LT L+ +++ +
Sbjct: 871 QLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKS 930
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
+ +++ T QL +SL+ + E ++ + S +EE+ +TK Q
Sbjct: 931 DIHDTVNMNIDTQEQLRNALESLK-QHQETINTLKSKISEEVSRNLHMEENTGETKDEFQ 989
Query: 391 EQ-CEITKREIELKERTETELQDSR-NAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
++ I K++ + T+T D + N I E Q KI L + K E I +L
Sbjct: 990 QKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQL 1049
Query: 449 QA-TKETLRVT---EDEVTTCKREKESENKIGIQQKLAA-----ELLNKEEIIGKMQIQT 499
+ KE + +T ++E+ E + + +I Q+K A EL + + +++ +
Sbjct: 1050 KTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKL 1109
Query: 500 RELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL-KMKLLD 558
+E + ++ +Q+++ ++ + ++Q I N + N + ++L E M+ +++L
Sbjct: 1110 KEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLK---NELKNKELTLEHMETERLELAQ 1166
Query: 559 VVHRNEELSEILAKKDQELEQQDKNSRGQARVIK--IREELINVLKNKETEQSRELAALQ 616
++ N E + + K+ + L++ K+ + ++ IRE L+ KE EL
Sbjct: 1167 KLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE-----ELKIAH 1221
Query: 617 QDLEHRMRIVDEVNKQIAAKADEI 640
L+ +DE+ + ++ K +I
Sbjct: 1222 IHLKEHQETIDELRRSVSEKTAQI 1245
Score = 61.3 bits (142), Expect = 1e-08
Identities = 111/551 (20%), Positives = 237/551 (43%), Gaps = 42/551 (7%)
Query: 142 ETMPIENIIKYPKTNLTVNQDQTDGDILEHLSR-YNDQGFELCGALRELKTQAEDAVNTV 200
ET +E K + V + +L+ L + + + L G +RE++ +
Sbjct: 1158 ETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEEL 1217
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKL--RQDVETRNVMI-DEIRELRSESENTKALEE 257
+ T+ + ++ + A++ QD+E + + +EI L E E ++E
Sbjct: 1218 KIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKE 1277
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLT---GTVKML 314
+ + +L ++ T + L + +++++ +E++ I SLT +K +
Sbjct: 1278 VSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTI 1337
Query: 315 EDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA 374
++ K QL+ R+ ++ + Q + ++ E + ++E+ + SA
Sbjct: 1338 KEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEK-DNETTKIVSEMEQFKPK-DSA 1395
Query: 375 IQQLEEDLKQTKRALQEQCE----ITKREIE---LKERTETELQDSRNAIEELQAKIIEL 427
+ ++E ++ + LQE + + K + + L+E ++E + I+E+ AK +E
Sbjct: 1396 LLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLET 1455
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
E+ + + + EL+ L E E++T +++ E+ N +Q K+ E+
Sbjct: 1456 EEELKVAHCCLKEQEETINELRV---NLSEKETEISTIQKQLEAIND-KLQNKI-QEIYE 1510
Query: 488 KEEIIGKMQI-QTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN-CQESPNGISYQDL 545
KEE QI + +E + +K ++ + ++ +++ + N QES I
Sbjct: 1511 KEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIK 1570
Query: 546 QQEIMDLKMKLLDVV--HRNEELSEILA--KKDQELEQQ-------DKNSRGQARVIKIR 594
++E M + L + E EI+A K+ QE E Q ++ + ++
Sbjct: 1571 EKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLK 1630
Query: 595 EEL----INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ-ELFATLEN 649
E+ +N L+N ETE R L ++LE MR V + + + + ++ E EN
Sbjct: 1631 EQFETQKLN-LENIETENIRLTQILHENLE-EMRSVTKERDDLRSVEETLKVERDQLKEN 1688
Query: 650 KQQQIHR-LEK 659
++ I R LEK
Sbjct: 1689 LRETITRDLEK 1699
Score = 54.0 bits (124), Expect = 2e-06
Identities = 89/454 (19%), Positives = 203/454 (44%), Gaps = 46/454 (10%)
Query: 224 EVAKLRQDVETRNVMIDE-IRELRSESENT----KALEEMRHELDEERTAKLAIKEKLTT 278
+++ +++D+E N + E I+EL++ K + E + ++ E K IK++ T
Sbjct: 1783 KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1842
Query: 279 TESQLRQTRNRVAKMDKQLREAEA------SITSLTGTVKMLEDQSRQKEVQLEARARKL 332
+ N K+ + L E ++ ++ + T+K+ DQ ++ + +AR ++
Sbjct: 1843 LSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI 1902
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
++ LKT + + + + D L +++I + T+Q I +++DL ++K LQ++
Sbjct: 1903 QQELKTARMLSKEHKETVDKL-------REKISEKTIQ----ISDIQKDLDKSKDELQKK 1951
Query: 393 CEITKREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTE----REIDLWAE 447
+ +++ ++R ++ Q ++ E ++I EL K D E +DL E
Sbjct: 1952 QDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKE 2011
Query: 448 LQATKE-TLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
++ KE ++RV + + K E Q+ + E I+ K++ + K
Sbjct: 2012 IEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEF---HRIMKKLKYVLSYVTKIK 2068
Query: 507 KLNEQKVIQYE-QYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
+ + + ++E ++ +++ + Q +E+ DLK+ +H
Sbjct: 2069 EEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVP--SRELRDLKLNQNMDLH---- 2122
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLK---NKETEQSRELAALQQDLEHR 622
+ EIL K E E + Q +V+ R+E+ L+ N + + +Q++ +
Sbjct: 2123 IEEIL-KDFSESEFPSIKTEFQ-QVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRI 2180
Query: 623 MRIVDEVNKQIAA---KADEIQELFATLENKQQQ 653
++ + N +I A ++ E +E AT+ + +Q
Sbjct: 2181 CQVNNFFNNRIIAIMNESTEFEERSATISKEWEQ 2214
Score = 53.2 bits (122), Expect = 3e-06
Identities = 87/441 (19%), Positives = 199/441 (45%), Gaps = 41/441 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR--EVAKLRQDVETR-----NVMID 240
+LK ++ V + + ++ ++ + AV E + E+ L++ ET+ N+ +
Sbjct: 1588 QLKENTKEIVAKMKESQEKE-YQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETE 1646
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
IR + EN + + + E D+ R+ + +K + + LR+T R + ++L+
Sbjct: 1647 NIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIV 1706
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
+ T+ L +K ++ + L S + ++ ++ + E
Sbjct: 1707 HMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQ 1766
Query: 361 KQQIEKLT--VQHKS-AIQQLEEDLKQTKRALQEQCE---------IT-KREIELKERTE 407
++ I+KL V K+ + +++DL+ + LQE+ + IT K+++ ++
Sbjct: 1767 QETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKV 1826
Query: 408 TELQDSRNAIEELQAKIIELE------KSKPNPDLPTEREIDLWAE-LQATKETLRVTED 460
+E++ + I++ + +LE K + +L + + + L+ +ETL++ D
Sbjct: 1827 SEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERD 1886
Query: 461 EVTTCKREKESENKIGIQQKL-AAELLNKE--EIIGKMQIQTRELIKNIKLNE-QKVIQY 516
++ +E ++ + + IQQ+L A +L+KE E + K++ + E K I++++ QK +
Sbjct: 1887 QLKESLQETKARD-LEIQQELKTARMLSKEHKETVDKLREKISE--KTIQISDIQKDLDK 1943
Query: 517 EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQE 576
+D + N Q P D QQ + + L + R +EL + ++ D
Sbjct: 1944 S---KDELQKKQDRQNHQVKPEKRLLSDGQQHLTE---SLREKCSRIKELLKRYSEMDDH 1997
Query: 577 LEQQDKNSRGQARVIKIREEL 597
E ++ S + I+ ++EL
Sbjct: 1998 YECLNRLSLDLEKEIEFQKEL 2018
Score = 53.2 bits (122), Expect = 3e-06
Identities = 118/529 (22%), Positives = 224/529 (42%), Gaps = 40/529 (7%)
Query: 159 VNQDQTDGDILEHLSRY-NDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAV 217
VN+ Q +E L + DQ L E A+ + ++ K ER L V
Sbjct: 1819 VNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEM-KSVMKERDNLRRV 1877
Query: 218 GEALVREVAKLR---QDVETRNVMID-EIRELRSES-ENTKALEEMRHELDEERTAKLAI 272
E L E +L+ Q+ + R++ I E++ R S E+ + ++++R ++ E+ I
Sbjct: 1878 EETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDI 1937
Query: 273 KEKLTTTESQLRQTRNRV---AKMDKQL-----REAEASITSLTGTVKMLEDQSRQKEVQ 324
++ L ++ +L++ ++R K +K+L + S+ +K L + + +
Sbjct: 1938 QKDLDKSKDELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDH 1997
Query: 325 LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ 384
E R + K E ++ + +L L+ K IEKL ++ + +K+
Sbjct: 1998 YECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKH-IEKLFTANQRCSMEFHRIMKK 2056
Query: 385 TKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL 444
K L +I + + E + E + D +EL KI L++ + D+P+ DL
Sbjct: 2057 LKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQ---DCDVPSRELRDL 2113
Query: 445 WAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ--IQTREL 502
+ + + +E+ K ESE I+ + L N++E+ ++ + TR
Sbjct: 2114 -----KLNQNMDLHIEEIL--KDFSESEFP-SIKTEFQQVLSNRKEMTQFLEEWLNTRFD 2165
Query: 503 IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP-----NGISYQDLQQEIMDLKMKLL 557
I+ +K QK V + +NR IA ES + ++ +Q++ LK K
Sbjct: 2166 IEKLKNGIQKENDRICQVNNF-FNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNE 2224
Query: 558 DVVHRNEELSEILAKKDQ--ELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAAL 615
+ + L LA Q Q +KN +R ++ E I L+N +++E A
Sbjct: 2225 KLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELEN-SLHEAKESAMH 2283
Query: 616 QQDLEHRMRIVDEVNKQIAAKAD-EIQELFATLENKQQQIHRL-EKIVL 662
++ +M+ EV I AK ++ E LE ++ I L +K+ L
Sbjct: 2284 KESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVAL 2332
Score = 38.7 bits (86), Expect = 0.069
Identities = 34/145 (23%), Positives = 70/145 (48%), Gaps = 11/145 (7%)
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
R+ T+ + E+ + L E + + + + K+ + +L T + +AK+ ++ E+ +
Sbjct: 2258 RATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLE 2317
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLR-ESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
T+++L+D +V L A+ K E LK V I A+ E +
Sbjct: 2318 KTKETIQVLQD-----KVALGAKPYKEEIEDLKMKLVK----IDLEKMKNAKEFEKEISA 2368
Query: 365 EKLTVQH-KSAIQQLEEDLKQTKRA 388
K TV++ K I+ L E+L+++++A
Sbjct: 2369 TKATVEYQKEVIRLLRENLRRSQQA 2393
>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
protein.
Length = 1337
Score = 78.6 bits (185), Expect = 7e-14
Identities = 102/472 (21%), Positives = 205/472 (43%), Gaps = 40/472 (8%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA----LVREVAKLRQDVETRN 236
ELC EL+ + + ++ CH+ + E L E K++Q+++
Sbjct: 894 ELCAEAEELRARLTAKKQELEEI----CHDLEARVEEEEERCQHLQAEKKKMQQNIQELE 949
Query: 237 VMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++E R + + K E + +L+EE+ + ++++ + + +R+A+
Sbjct: 950 EQLEEEESARQKLQLEKVTTEAKLKKLEEEQ---IILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDS 352
L E E SL E E +L ++ +E KT E ++ L Q
Sbjct: 1007 NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
LQA++ E K Q+ K + ++A+ ++EE+ Q AL++ E+ + EL+E E+E +
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE-RA 1125
Query: 413 SRNAIEELQAKI-IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES 471
SRN E+ + + ELE L TE E D A +E E EV K+ E
Sbjct: 1126 SRNKAEKQKRDLGEELEA------LKTELE-DTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
E K + E+ K + + E K +K N +K Q + R A+ +
Sbjct: 1179 EAK--THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ + + ++ ++ +L++K + E + LA K +L+ + N G
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQELQVKF----NEGERVRTELADKVTKLQVELDNVTG----- 1287
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
L++ +K ++ +++ +AL+ L+ ++ E N+Q + + +++++
Sbjct: 1288 -----LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQV 1334
Score = 72.9 bits (171), Expect = 3e-12
Identities = 109/472 (23%), Positives = 206/472 (43%), Gaps = 40/472 (8%)
Query: 203 LSKRACHERRTLIAVGEALVREVA---KLRQDVETRNVMIDEIRELRSESENTKALEEMR 259
L+++A +R+ + + L R A KLR R + +++ L S + +
Sbjct: 794 LARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWR--LFTKVKPLLQVSRQEEEMMAKE 851
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR 319
EL + R +LA + +LT E+ Q ++ +QL +AE T L + L +
Sbjct: 852 EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQL-QAE---TELCAEAEELRARLT 907
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQ--Q 377
K+ +LE L ++ E L ++ +Q + E ++Q+E + +SA Q Q
Sbjct: 908 AKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE----EEESARQKLQ 963
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKII-ELEKSKPNPDL 436
LE+ + K E+ +I + K E +L + R I E + E EKSK L
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDR--IAEFTTNLTEEEEKSKSLAKL 1021
Query: 437 PTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ 496
+ E A + +E LR + EK+ + ++KL + + + I ++Q
Sbjct: 1022 KNKHE----AMITDLEERLR---------REEKQRQELEKTRRKLEGDSTDLSDQIAELQ 1068
Query: 497 IQTRELIKNIKLNEQKVIQYEQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMK 555
Q EL + E+++ V + A N + +E + IS +LQ+++ +
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQIS--ELQEDLESERAS 1126
Query: 556 LLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAA 614
+ +L E L ELE ++ Q + RE+ +N+LK E E A
Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ 1186
Query: 615 LQQDLEHRMRIVDEVNKQI----AAKADEIQELFATLENKQQQIHRLEKIVL 662
+Q+ + + V+E+ +Q+ KA+ +++ TLEN++ ++ K++L
Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKAN-LEKAKQTLENERGELANEVKVLL 1237
>BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 78.6 bits (185), Expect = 7e-14
Identities = 109/465 (23%), Positives = 202/465 (43%), Gaps = 32/465 (6%)
Query: 249 SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLR-QTRNRVAKMDKQLREAEASITSL 307
+E TK E R E + EK+ T +LR Q N +M +L+E I L
Sbjct: 194 AEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHL 253
Query: 308 TGTVKM-LEDQSRQKE---VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
K + D+ +Q +Q+ + K+++ E + ++ Q + + + KQ
Sbjct: 254 EQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 364 IEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEI-TKREIELKERTETELQDSRNAIEE 419
IEK LT + + L+ + T++AL+E +I TK +L E ET++++S A
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVS-TQKALEEDLQIATKTICQLTEEKETQMEESNKARAA 372
Query: 420 LQAKIIELEKSKPNPD--LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ E E + + + L TE++ L+ ++ L++ E+ E E K+
Sbjct: 373 HSFVVTEFETTVCSLEELLRTEQQ-----RLEKNEDQLKILTMELQKKSSELEEMTKLTN 427
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+++ E L K ++G+ + E + K+ E+ ++ + LQA + + + +
Sbjct: 428 NKEVELEELKK--VLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQL 485
Query: 538 NGI--SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
I S Q +E+ DLK +L + +N EL+ K E ++ + + +K ++
Sbjct: 486 TAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQ 545
Query: 596 ELINVLKNKETEQSRELAALQQ---DLEHRMRIVDEVNKQ----IAAKADEIQE----LF 644
E IN K +E +++ LQ+ L + + V E KQ + K D+ +E L
Sbjct: 546 EDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Query: 645 ATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHEL 689
+ENK + I L++ AL K+ LE EL
Sbjct: 606 KQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELEL 650
Score = 76.2 bits (179), Expect = 4e-13
Identities = 106/499 (21%), Positives = 223/499 (44%), Gaps = 53/499 (10%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV----AKLRQDVETRNVMIDEIR- 243
L ++ D VN + + +K + I L +E+ L++ V T+ + ++++
Sbjct: 288 LLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQI 347
Query: 244 ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT----ESQLRQTRNRVAKMDKQLRE 299
++ + T+ E E ++ R A + + TT E LR + R+ K + QL+
Sbjct: 348 ATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKL--RESL--------KTGEV---TTSQL 346
+ + ++ + + KEV+LE + L +E+L K E T +L
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQEL 467
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQ---HKSAIQQLEEDLKQTK---RALQEQC-EITKRE 399
I + + EV + + Q+ +T + ++ L+ +L+ K L C +++
Sbjct: 468 IGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLEN 527
Query: 400 IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
EL + T + +N E++ + E+ + E E L EL+ +E L+
Sbjct: 528 KELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKR 587
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
DEV CK +K EN +++++ NK + I ++Q + + L K +++ YE
Sbjct: 588 DEVK-CKLDKSEENCNNLRKQVE----NKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK---LLDVVHRNEELSEILAKKDQE 576
V L+ + + ++ I+ Q+EI D K+ LL+ V + + +++ K +E
Sbjct: 643 VNKLELE---LESAKQKFGEIT-DTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKE 698
Query: 577 LEQQ------------DKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
++++ +K+ ++I+ R+ + + K+KE EQS A+L+ +L +
Sbjct: 699 IDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Query: 625 IVDEVNKQIAAKADEIQEL 643
+ V KQ+ + +E ++L
Sbjct: 759 ELLSVKKQLEIEREEKEKL 777
Score = 73.3 bits (172), Expect = 3e-12
Identities = 91/477 (19%), Positives = 206/477 (43%), Gaps = 23/477 (4%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
+C E +TQ E++ S T+ ++ E L E +L ++ + ++ E
Sbjct: 352 ICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTME 411
Query: 242 IRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--- 297
+++ SE E TK EL+E + L KE L Q + + +++L
Sbjct: 412 LQKKSSELEEMTKLTNNKEVELEELKKV-LGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 298 ---REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
RE E + T +Q KEV + L+ L+ ++ ++L + L
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYYSKEV------KDLKTELENEKLKNTELTSHCNKLS 524
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
E E Q+ +T++ K+ + + + KQ +R L++ + + E +L+ E ++ +
Sbjct: 525 LENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELK 584
Query: 415 NAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
+E++ K+ + E++ N E + ELQ + L+ + K+ E K
Sbjct: 585 QKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALK--KKGTAESKQLNVYEIK 642
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ 534
+ KL EL + ++ G++ ++ I++ K++E+ +++ + + + + + +
Sbjct: 643 VN---KLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIA--DEAVKLQK 697
Query: 535 ESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
E ++ + +M+ D + + SE+ K +E EQ + + + +
Sbjct: 698 EIDKRCQHKIAEMVALMEKHKHQYDKIIEERD-SELGLYKSKEQEQSSLRASLEIELSNL 756
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
+ EL++V K E E+ + ++ E+ + ++ +K+ E E++ L++K
Sbjct: 757 KAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIYWKLDSK 813
Score = 54.0 bits (124), Expect = 2e-06
Identities = 96/442 (21%), Positives = 190/442 (42%), Gaps = 25/442 (5%)
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
E+R+ + + + +SEN K E +H L +E ++ +T+ L + K
Sbjct: 291 ESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATK 350
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
QL E + T + + K S + E L E L+T + + Q
Sbjct: 351 TICQLTEEKE--TQMEESNKARAAHS-FVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 353 LQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
L E+ + ++E KLT + +++L++ L + + L E + K ELK TE E
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELK-GTEQE 466
Query: 410 LQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE 468
L A E E+ I+L + ++ DL EL+ E L+ T E+T+ +
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELE--NEKLKNT--ELTSHCNK 522
Query: 469 KESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIK---NIKLNEQKVIQYEQYVRDL 523
ENK Q+ + EL N++E I + Q ++K N++ E ++ +YVR+
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD-K 582
R C+ + + +L++++ + + ++ N+ L + + ++L + K
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 583 NSRGQARVIKIREEL--INVLKNKETEQSR-ELAALQQDLEHRMRIVDE---VNKQIAAK 636
++ + + +++ I KE E + L +++E I DE + K+I +
Sbjct: 643 VNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKR 702
Query: 637 AD-EIQELFATLENKQQQIHRL 657
+I E+ A +E + Q ++
Sbjct: 703 CQHKIAEMVALMEKHKHQYDKI 724
Score = 50.8 bits (116), Expect = 2e-05
Identities = 93/436 (21%), Positives = 203/436 (46%), Gaps = 71/436 (16%)
Query: 247 SESENTKALEEMRHELDEE----RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
S+ EN++ L + +L +E + K++ + +L ES+L++ R + K ++E +
Sbjct: 94 SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQF 153
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEV 357
++ +K+ E K++ E A + L+E+ T + +R+ +
Sbjct: 154 GNEKVS--LKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVY 211
Query: 358 LECKQQIEK-------LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTET-- 408
++ IEK L VQ +++ ++ LK+ +Q + K+EI KE+ +
Sbjct: 212 MDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL 271
Query: 409 --ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
++ + N +++L ++E + K N +++ +LQ+ E L+ + ++
Sbjct: 272 LIQITEKENKMKDL-TFLLEESRDKVN-------QLEEKTKLQS--ENLKQSIEKQHHLT 321
Query: 467 REKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
+E E + K+ +Q+ ++ + +E+ +QI T+ + +L E+K Q E+ + AH
Sbjct: 322 KELE-DIKVSLQRSVSTQKALEED----LQIATKTI---CQLTEEKETQMEESNKARAAH 373
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+ + + + + +E++ + + L+ +NE+ +IL +E Q K+S
Sbjct: 374 SFVVTEFETTVCSL------EELLRTEQQRLE---KNEDQLKILT-----MELQKKSSE- 418
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI----QE 642
EE+ + NKE EL L++ L + ++ E NKQ A+E+ QE
Sbjct: 419 -------LEEMTKLTNNKEV----ELEELKKVLGEKETLLYE-NKQFEKIAEELKGTEQE 466
Query: 643 LFATLENKQQQIHRLE 658
L L+ +++++H LE
Sbjct: 467 LIGLLQAREKEVHDLE 482
>AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 78.6 bits (185), Expect = 7e-14
Identities = 109/465 (23%), Positives = 202/465 (43%), Gaps = 32/465 (6%)
Query: 249 SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLR-QTRNRVAKMDKQLREAEASITSL 307
+E TK E R E + EK+ T +LR Q N +M +L+E I L
Sbjct: 194 AEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHL 253
Query: 308 TGTVKM-LEDQSRQKE---VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
K + D+ +Q +Q+ + K+++ E + ++ Q + + + KQ
Sbjct: 254 EQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 364 IEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEI-TKREIELKERTETELQDSRNAIEE 419
IEK LT + + L+ + T++AL+E +I TK +L E ET++++S A
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVS-TQKALEEDLQIATKTICQLTEEKETQMEESNKARAA 372
Query: 420 LQAKIIELEKSKPNPD--LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ E E + + + L TE++ L+ ++ L++ E+ E E K+
Sbjct: 373 HSFVVTEFETTVCSLEELLRTEQQ-----RLEKNEDQLKILTMELQKKSSELEEMTKLTN 427
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+++ E L K ++G+ + E + K+ E+ ++ + LQA + + + +
Sbjct: 428 NKEVELEELKK--VLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQL 485
Query: 538 NGI--SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
I S Q +E+ DLK +L + +N EL+ K E ++ + + +K ++
Sbjct: 486 TAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQ 545
Query: 596 ELINVLKNKETEQSRELAALQQ---DLEHRMRIVDEVNKQ----IAAKADEIQE----LF 644
E IN K +E +++ LQ+ L + + V E KQ + K D+ +E L
Sbjct: 546 EDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Query: 645 ATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHEL 689
+ENK + I L++ AL K+ LE EL
Sbjct: 606 KQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELEL 650
Score = 76.2 bits (179), Expect = 4e-13
Identities = 106/499 (21%), Positives = 223/499 (44%), Gaps = 53/499 (10%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV----AKLRQDVETRNVMIDEIR- 243
L ++ D VN + + +K + I L +E+ L++ V T+ + ++++
Sbjct: 288 LLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQI 347
Query: 244 ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT----ESQLRQTRNRVAKMDKQLRE 299
++ + T+ E E ++ R A + + TT E LR + R+ K + QL+
Sbjct: 348 ATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKL--RESL--------KTGEV---TTSQL 346
+ + ++ + + KEV+LE + L +E+L K E T +L
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQEL 467
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQ---HKSAIQQLEEDLKQTK---RALQEQC-EITKRE 399
I + + EV + + Q+ +T + ++ L+ +L+ K L C +++
Sbjct: 468 IGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLEN 527
Query: 400 IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
EL + T + +N E++ + E+ + E E L EL+ +E L+
Sbjct: 528 KELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKR 587
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
DEV CK +K EN +++++ NK + I ++Q + + L K +++ YE
Sbjct: 588 DEVK-CKLDKSEENCNNLRKQVE----NKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK---LLDVVHRNEELSEILAKKDQE 576
V L+ + + ++ I+ Q+EI D K+ LL+ V + + +++ K +E
Sbjct: 643 VNKLELE---LESAKQKFGEIT-DTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKE 698
Query: 577 LEQQ------------DKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
++++ +K+ ++I+ R+ + + K+KE EQS A+L+ +L +
Sbjct: 699 IDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Query: 625 IVDEVNKQIAAKADEIQEL 643
+ V KQ+ + +E ++L
Sbjct: 759 ELLSVKKQLEIEREEKEKL 777
Score = 73.3 bits (172), Expect = 3e-12
Identities = 91/477 (19%), Positives = 206/477 (43%), Gaps = 23/477 (4%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
+C E +TQ E++ S T+ ++ E L E +L ++ + ++ E
Sbjct: 352 ICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTME 411
Query: 242 IRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--- 297
+++ SE E TK EL+E + L KE L Q + + +++L
Sbjct: 412 LQKKSSELEEMTKLTNNKEVELEELKKV-LGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 298 ---REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
RE E + T +Q KEV + L+ L+ ++ ++L + L
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYYSKEV------KDLKTELENEKLKNTELTSHCNKLS 524
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
E E Q+ +T++ K+ + + + KQ +R L++ + + E +L+ E ++ +
Sbjct: 525 LENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELK 584
Query: 415 NAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
+E++ K+ + E++ N E + ELQ + L+ + K+ E K
Sbjct: 585 QKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALK--KKGTAESKQLNVYEIK 642
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ 534
+ KL EL + ++ G++ ++ I++ K++E+ +++ + + + + + +
Sbjct: 643 VN---KLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIA--DEAVKLQK 697
Query: 535 ESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
E ++ + +M+ D + + SE+ K +E EQ + + + +
Sbjct: 698 EIDKRCQHKIAEMVALMEKHKHQYDKIIEERD-SELGLYKSKEQEQSSLRASLEIELSNL 756
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
+ EL++V K E E+ + ++ E+ + ++ +K+ E E++ L++K
Sbjct: 757 KAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIYWKLDSK 813
Score = 54.0 bits (124), Expect = 2e-06
Identities = 96/442 (21%), Positives = 190/442 (42%), Gaps = 25/442 (5%)
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
E+R+ + + + +SEN K E +H L +E ++ +T+ L + K
Sbjct: 291 ESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATK 350
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
QL E + T + + K S + E L E L+T + + Q
Sbjct: 351 TICQLTEEKE--TQMEESNKARAAHS-FVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 353 LQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
L E+ + ++E KLT + +++L++ L + + L E + K ELK TE E
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELK-GTEQE 466
Query: 410 LQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE 468
L A E E+ I+L + ++ DL EL+ E L+ T E+T+ +
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELE--NEKLKNT--ELTSHCNK 522
Query: 469 KESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIK---NIKLNEQKVIQYEQYVRDL 523
ENK Q+ + EL N++E I + Q ++K N++ E ++ +YVR+
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD-K 582
R C+ + + +L++++ + + ++ N+ L + + ++L + K
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 583 NSRGQARVIKIREEL--INVLKNKETEQSR-ELAALQQDLEHRMRIVDE---VNKQIAAK 636
++ + + +++ I KE E + L +++E I DE + K+I +
Sbjct: 643 VNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKR 702
Query: 637 AD-EIQELFATLENKQQQIHRL 657
+I E+ A +E + Q ++
Sbjct: 703 CQHKIAEMVALMEKHKHQYDKI 724
Score = 50.8 bits (116), Expect = 2e-05
Identities = 93/436 (21%), Positives = 203/436 (46%), Gaps = 71/436 (16%)
Query: 247 SESENTKALEEMRHELDEE----RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
S+ EN++ L + +L +E + K++ + +L ES+L++ R + K ++E +
Sbjct: 94 SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQF 153
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEV 357
++ +K+ E K++ E A + L+E+ T + +R+ +
Sbjct: 154 GNEKVS--LKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVY 211
Query: 358 LECKQQIEK-------LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTET-- 408
++ IEK L VQ +++ ++ LK+ +Q + K+EI KE+ +
Sbjct: 212 MDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL 271
Query: 409 --ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
++ + N +++L ++E + K N +++ +LQ+ E L+ + ++
Sbjct: 272 LIQITEKENKMKDL-TFLLEESRDKVN-------QLEEKTKLQS--ENLKQSIEKQHHLT 321
Query: 467 REKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
+E E + K+ +Q+ ++ + +E+ +QI T+ + +L E+K Q E+ + AH
Sbjct: 322 KELE-DIKVSLQRSVSTQKALEED----LQIATKTI---CQLTEEKETQMEESNKARAAH 373
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+ + + + + +E++ + + L+ +NE+ +IL +E Q K+S
Sbjct: 374 SFVVTEFETTVCSL------EELLRTEQQRLE---KNEDQLKILT-----MELQKKSSE- 418
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI----QE 642
EE+ + NKE EL L++ L + ++ E NKQ A+E+ QE
Sbjct: 419 -------LEEMTKLTNNKEV----ELEELKKVLGEKETLLYE-NKQFEKIAEELKGTEQE 466
Query: 643 LFATLENKQQQIHRLE 658
L L+ +++++H LE
Sbjct: 467 LIGLLQAREKEVHDLE 482
>AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 792
Score = 78.6 bits (185), Expect = 7e-14
Identities = 109/465 (23%), Positives = 202/465 (43%), Gaps = 32/465 (6%)
Query: 249 SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLR-QTRNRVAKMDKQLREAEASITSL 307
+E TK E R E + EK+ T +LR Q N +M +L+E I L
Sbjct: 194 AEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHL 253
Query: 308 TGTVKM-LEDQSRQKE---VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
K + D+ +Q +Q+ + K+++ E + ++ Q + + + KQ
Sbjct: 254 EQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 364 IEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEI-TKREIELKERTETELQDSRNAIEE 419
IEK LT + + L+ + T++AL+E +I TK +L E ET++++S A
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVS-TQKALEEDLQIATKTICQLTEEKETQMEESNKARAA 372
Query: 420 LQAKIIELEKSKPNPD--LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ E E + + + L TE++ L+ ++ L++ E+ E E K+
Sbjct: 373 HSFVVTEFETTVCSLEELLRTEQQ-----RLEKNEDQLKILTMELQKKSSELEEMTKLTN 427
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+++ E L K ++G+ + E + K+ E+ ++ + LQA + + + +
Sbjct: 428 NKEVELEELKK--VLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQL 485
Query: 538 NGI--SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
I S Q +E+ DLK +L + +N EL+ K E ++ + + +K ++
Sbjct: 486 TAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQ 545
Query: 596 ELINVLKNKETEQSRELAALQQ---DLEHRMRIVDEVNKQ----IAAKADEIQE----LF 644
E IN K +E +++ LQ+ L + + V E KQ + K D+ +E L
Sbjct: 546 EDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Query: 645 ATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHEL 689
+ENK + I L++ AL K+ LE EL
Sbjct: 606 KQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELEL 650
Score = 76.2 bits (179), Expect = 4e-13
Identities = 106/499 (21%), Positives = 223/499 (44%), Gaps = 53/499 (10%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV----AKLRQDVETRNVMIDEIR- 243
L ++ D VN + + +K + I L +E+ L++ V T+ + ++++
Sbjct: 288 LLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQI 347
Query: 244 ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT----ESQLRQTRNRVAKMDKQLRE 299
++ + T+ E E ++ R A + + TT E LR + R+ K + QL+
Sbjct: 348 ATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKL--RESL--------KTGEV---TTSQL 346
+ + ++ + + KEV+LE + L +E+L K E T +L
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQEL 467
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQ---HKSAIQQLEEDLKQTK---RALQEQC-EITKRE 399
I + + EV + + Q+ +T + ++ L+ +L+ K L C +++
Sbjct: 468 IGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLEN 527
Query: 400 IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
EL + T + +N E++ + E+ + E E L EL+ +E L+
Sbjct: 528 KELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKR 587
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
DEV CK +K EN +++++ NK + I ++Q + + L K +++ YE
Sbjct: 588 DEVK-CKLDKSEENCNNLRKQVE----NKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK---LLDVVHRNEELSEILAKKDQE 576
V L+ + + ++ I+ Q+EI D K+ LL+ V + + +++ K +E
Sbjct: 643 VNKLELE---LESAKQKFGEIT-DTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKE 698
Query: 577 LEQQ------------DKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
++++ +K+ ++I+ R+ + + K+KE EQS A+L+ +L +
Sbjct: 699 IDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Query: 625 IVDEVNKQIAAKADEIQEL 643
+ V KQ+ + +E ++L
Sbjct: 759 ELLSVKKQLEIEREEKEKL 777
Score = 54.0 bits (124), Expect = 2e-06
Identities = 96/442 (21%), Positives = 190/442 (42%), Gaps = 25/442 (5%)
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
E+R+ + + + +SEN K E +H L +E ++ +T+ L + K
Sbjct: 291 ESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATK 350
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
QL E + T + + K S + E L E L+T + + Q
Sbjct: 351 TICQLTEEKE--TQMEESNKARAAHS-FVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 353 LQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
L E+ + ++E KLT + +++L++ L + + L E + K ELK TE E
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELK-GTEQE 466
Query: 410 LQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE 468
L A E E+ I+L + ++ DL EL+ E L+ T E+T+ +
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELE--NEKLKNT--ELTSHCNK 522
Query: 469 KESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIK---NIKLNEQKVIQYEQYVRDL 523
ENK Q+ + EL N++E I + Q ++K N++ E ++ +YVR+
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD-K 582
R C+ + + +L++++ + + ++ N+ L + + ++L + K
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 583 NSRGQARVIKIREEL--INVLKNKETEQSR-ELAALQQDLEHRMRIVDE---VNKQIAAK 636
++ + + +++ I KE E + L +++E I DE + K+I +
Sbjct: 643 VNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKR 702
Query: 637 AD-EIQELFATLENKQQQIHRL 657
+I E+ A +E + Q ++
Sbjct: 703 CQHKIAEMVALMEKHKHQYDKI 724
Score = 50.8 bits (116), Expect = 2e-05
Identities = 93/436 (21%), Positives = 203/436 (46%), Gaps = 71/436 (16%)
Query: 247 SESENTKALEEMRHELDEE----RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
S+ EN++ L + +L +E + K++ + +L ES+L++ R + K ++E +
Sbjct: 94 SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQF 153
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEV 357
++ +K+ E K++ E A + L+E+ T + +R+ +
Sbjct: 154 GNEKVS--LKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVY 211
Query: 358 LECKQQIEK-------LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTET-- 408
++ IEK L VQ +++ ++ LK+ +Q + K+EI KE+ +
Sbjct: 212 MDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL 271
Query: 409 --ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
++ + N +++L ++E + K N +++ +LQ+ E L+ + ++
Sbjct: 272 LIQITEKENKMKDL-TFLLEESRDKVN-------QLEEKTKLQS--ENLKQSIEKQHHLT 321
Query: 467 REKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
+E E + K+ +Q+ ++ + +E+ +QI T+ + +L E+K Q E+ + AH
Sbjct: 322 KELE-DIKVSLQRSVSTQKALEED----LQIATKTI---CQLTEEKETQMEESNKARAAH 373
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+ + + + + +E++ + + L+ +NE+ +IL +E Q K+S
Sbjct: 374 SFVVTEFETTVCSL------EELLRTEQQRLE---KNEDQLKILT-----MELQKKSSE- 418
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI----QE 642
EE+ + NKE EL L++ L + ++ E NKQ A+E+ QE
Sbjct: 419 -------LEEMTKLTNNKEV----ELEELKKVLGEKETLLYE-NKQFEKIAEELKGTEQE 466
Query: 643 LFATLENKQQQIHRLE 658
L L+ +++++H LE
Sbjct: 467 LIGLLQAREKEVHDLE 482
Score = 50.4 bits (115), Expect = 2e-05
Identities = 66/305 (21%), Positives = 136/305 (44%), Gaps = 22/305 (7%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACH----ERRTLIAVGEALVREVAKLRQDVETRNV---- 237
+++LKT+ E+ T+L+ C+ E + L + E+ ++D+
Sbjct: 499 VKDLKTELENEKLKNTELTSH-CNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEER 557
Query: 238 MIDEIRELR-SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQ 296
M+ +I L+ +E++ LE +R EL ++R +K KL +E R +V +K
Sbjct: 558 MLKQIENLQETETQLRNELEYVREELKQKRDE---VKCKLDKSEENCNNLRKQVENKNKY 614
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL-KTGEVTTSQLIQQRDSLQA 355
+ E + +L Q E+++ +L + K GE+T + + D +
Sbjct: 615 IEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKIS 674
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
E +++EK V A++ +E K+ + + E + ++ K + + +++ +
Sbjct: 675 EE-NLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKH---KHQYDKIIEERDS 730
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+ ++K E E+S L E +L AEL + K+ L + +E KRE + EN
Sbjct: 731 ELGLYKSK--EQEQSSLRASLEIELS-NLKAELLSVKKQLEIEREEKEKLKREAK-ENTA 786
Query: 476 GIQQK 480
+++K
Sbjct: 787 TLKEK 791
>AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 78.6 bits (185), Expect = 7e-14
Identities = 109/465 (23%), Positives = 202/465 (43%), Gaps = 32/465 (6%)
Query: 249 SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLR-QTRNRVAKMDKQLREAEASITSL 307
+E TK E R E + EK+ T +LR Q N +M +L+E I L
Sbjct: 194 AEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHL 253
Query: 308 TGTVKM-LEDQSRQKE---VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
K + D+ +Q +Q+ + K+++ E + ++ Q + + + KQ
Sbjct: 254 EQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 364 IEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEI-TKREIELKERTETELQDSRNAIEE 419
IEK LT + + L+ + T++AL+E +I TK +L E ET++++S A
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVS-TQKALEEDLQIATKTICQLTEEKETQMEESNKARAA 372
Query: 420 LQAKIIELEKSKPNPD--LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ E E + + + L TE++ L+ ++ L++ E+ E E K+
Sbjct: 373 HSFVVTEFETTVCSLEELLRTEQQ-----RLEKNEDQLKILTMELQKKSSELEEMTKLTN 427
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+++ E L K ++G+ + E + K+ E+ ++ + LQA + + + +
Sbjct: 428 NKEVELEELKK--VLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQL 485
Query: 538 NGI--SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
I S Q +E+ DLK +L + +N EL+ K E ++ + + +K ++
Sbjct: 486 TAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQ 545
Query: 596 ELINVLKNKETEQSRELAALQQ---DLEHRMRIVDEVNKQ----IAAKADEIQE----LF 644
E IN K +E +++ LQ+ L + + V E KQ + K D+ +E L
Sbjct: 546 EDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Query: 645 ATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHEL 689
+ENK + I L++ AL K+ LE EL
Sbjct: 606 KQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELEL 650
Score = 76.2 bits (179), Expect = 4e-13
Identities = 106/499 (21%), Positives = 223/499 (44%), Gaps = 53/499 (10%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV----AKLRQDVETRNVMIDEIR- 243
L ++ D VN + + +K + I L +E+ L++ V T+ + ++++
Sbjct: 288 LLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQI 347
Query: 244 ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT----ESQLRQTRNRVAKMDKQLRE 299
++ + T+ E E ++ R A + + TT E LR + R+ K + QL+
Sbjct: 348 ATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKL--RESL--------KTGEV---TTSQL 346
+ + ++ + + KEV+LE + L +E+L K E T +L
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQEL 467
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQ---HKSAIQQLEEDLKQTK---RALQEQC-EITKRE 399
I + + EV + + Q+ +T + ++ L+ +L+ K L C +++
Sbjct: 468 IGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLEN 527
Query: 400 IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
EL + T + +N E++ + E+ + E E L EL+ +E L+
Sbjct: 528 KELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKR 587
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
DEV CK +K EN +++++ NK + I ++Q + + L K +++ YE
Sbjct: 588 DEVK-CKLDKSEENCNNLRKQVE----NKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK---LLDVVHRNEELSEILAKKDQE 576
V L+ + + ++ I+ Q+EI D K+ LL+ V + + +++ K +E
Sbjct: 643 VNKLELE---LESAKQKFGEIT-DTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKE 698
Query: 577 LEQQ------------DKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
++++ +K+ ++I+ R+ + + K+KE EQS A+L+ +L +
Sbjct: 699 IDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Query: 625 IVDEVNKQIAAKADEIQEL 643
+ V KQ+ + +E ++L
Sbjct: 759 ELLSVKKQLEIEREEKEKL 777
Score = 73.3 bits (172), Expect = 3e-12
Identities = 91/477 (19%), Positives = 206/477 (43%), Gaps = 23/477 (4%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
+C E +TQ E++ S T+ ++ E L E +L ++ + ++ E
Sbjct: 352 ICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTME 411
Query: 242 IRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--- 297
+++ SE E TK EL+E + L KE L Q + + +++L
Sbjct: 412 LQKKSSELEEMTKLTNNKEVELEELKKV-LGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 298 ---REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
RE E + T +Q KEV + L+ L+ ++ ++L + L
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYYSKEV------KDLKTELENEKLKNTELTSHCNKLS 524
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
E E Q+ +T++ K+ + + + KQ +R L++ + + E +L+ E ++ +
Sbjct: 525 LENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELK 584
Query: 415 NAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
+E++ K+ + E++ N E + ELQ + L+ + K+ E K
Sbjct: 585 QKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALK--KKGTAESKQLNVYEIK 642
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ 534
+ KL EL + ++ G++ ++ I++ K++E+ +++ + + + + + +
Sbjct: 643 VN---KLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIA--DEAVKLQK 697
Query: 535 ESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
E ++ + +M+ D + + SE+ K +E EQ + + + +
Sbjct: 698 EIDKRCQHKIAEMVALMEKHKHQYDKIIEERD-SELGLYKSKEQEQSSLRASLEIELSNL 756
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
+ EL++V K E E+ + ++ E+ + ++ +K+ E E++ L++K
Sbjct: 757 KAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIYWKLDSK 813
Score = 54.0 bits (124), Expect = 2e-06
Identities = 96/442 (21%), Positives = 190/442 (42%), Gaps = 25/442 (5%)
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
E+R+ + + + +SEN K E +H L +E ++ +T+ L + K
Sbjct: 291 ESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATK 350
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
QL E + T + + K S + E L E L+T + + Q
Sbjct: 351 TICQLTEEKE--TQMEESNKARAAHS-FVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 353 LQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
L E+ + ++E KLT + +++L++ L + + L E + K ELK TE E
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELK-GTEQE 466
Query: 410 LQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE 468
L A E E+ I+L + ++ DL EL+ E L+ T E+T+ +
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELE--NEKLKNT--ELTSHCNK 522
Query: 469 KESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIK---NIKLNEQKVIQYEQYVRDL 523
ENK Q+ + EL N++E I + Q ++K N++ E ++ +YVR+
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD-K 582
R C+ + + +L++++ + + ++ N+ L + + ++L + K
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 583 NSRGQARVIKIREEL--INVLKNKETEQSR-ELAALQQDLEHRMRIVDE---VNKQIAAK 636
++ + + +++ I KE E + L +++E I DE + K+I +
Sbjct: 643 VNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKR 702
Query: 637 AD-EIQELFATLENKQQQIHRL 657
+I E+ A +E + Q ++
Sbjct: 703 CQHKIAEMVALMEKHKHQYDKI 724
Score = 50.8 bits (116), Expect = 2e-05
Identities = 93/436 (21%), Positives = 203/436 (46%), Gaps = 71/436 (16%)
Query: 247 SESENTKALEEMRHELDEE----RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
S+ EN++ L + +L +E + K++ + +L ES+L++ R + K ++E +
Sbjct: 94 SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQF 153
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEV 357
++ +K+ E K++ E A + L+E+ T + +R+ +
Sbjct: 154 GNEKVS--LKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVY 211
Query: 358 LECKQQIEK-------LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTET-- 408
++ IEK L VQ +++ ++ LK+ +Q + K+EI KE+ +
Sbjct: 212 MDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL 271
Query: 409 --ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
++ + N +++L ++E + K N +++ +LQ+ E L+ + ++
Sbjct: 272 LIQITEKENKMKDL-TFLLEESRDKVN-------QLEEKTKLQS--ENLKQSIEKQHHLT 321
Query: 467 REKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
+E E + K+ +Q+ ++ + +E+ +QI T+ + +L E+K Q E+ + AH
Sbjct: 322 KELE-DIKVSLQRSVSTQKALEED----LQIATKTI---CQLTEEKETQMEESNKARAAH 373
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+ + + + + +E++ + + L+ +NE+ +IL +E Q K+S
Sbjct: 374 SFVVTEFETTVCSL------EELLRTEQQRLE---KNEDQLKILT-----MELQKKSSE- 418
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI----QE 642
EE+ + NKE EL L++ L + ++ E NKQ A+E+ QE
Sbjct: 419 -------LEEMTKLTNNKEV----ELEELKKVLGEKETLLYE-NKQFEKIAEELKGTEQE 466
Query: 643 LFATLENKQQQIHRLE 658
L L+ +++++H LE
Sbjct: 467 LIGLLQAREKEVHDLE 482
>AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-1
protein.
Length = 795
Score = 78.6 bits (185), Expect = 7e-14
Identities = 109/465 (23%), Positives = 202/465 (43%), Gaps = 32/465 (6%)
Query: 249 SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLR-QTRNRVAKMDKQLREAEASITSL 307
+E TK E R E + EK+ T +LR Q N +M +L+E I L
Sbjct: 194 AEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHL 253
Query: 308 TGTVKM-LEDQSRQKE---VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
K + D+ +Q +Q+ + K+++ E + ++ Q + + + KQ
Sbjct: 254 EQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 364 IEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEI-TKREIELKERTETELQDSRNAIEE 419
IEK LT + + L+ + T++AL+E +I TK +L E ET++++S A
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVS-TQKALEEDLQIATKTICQLTEEKETQMEESNKARAA 372
Query: 420 LQAKIIELEKSKPNPD--LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
+ E E + + + L TE++ L+ ++ L++ E+ E E K+
Sbjct: 373 HSFVVTEFETTVCSLEELLRTEQQ-----RLEKNEDQLKILTMELQKKSSELEEMTKLTN 427
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+++ E L K ++G+ + E + K+ E+ ++ + LQA + + + +
Sbjct: 428 NKEVELEELKK--VLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKEVHDLEIQL 485
Query: 538 NGI--SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
I S Q +E+ DLK +L + +N EL+ K E ++ + + +K ++
Sbjct: 486 TAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQ 545
Query: 596 ELINVLKNKETEQSRELAALQQ---DLEHRMRIVDEVNKQ----IAAKADEIQE----LF 644
E IN K +E +++ LQ+ L + + V E KQ + K D+ +E L
Sbjct: 546 EDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Query: 645 ATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHEL 689
+ENK + I L++ AL K+ LE EL
Sbjct: 606 KQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELEL 650
Score = 76.2 bits (179), Expect = 4e-13
Identities = 106/499 (21%), Positives = 223/499 (44%), Gaps = 53/499 (10%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV----AKLRQDVETRNVMIDEIR- 243
L ++ D VN + + +K + I L +E+ L++ V T+ + ++++
Sbjct: 288 LLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQI 347
Query: 244 ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT----ESQLRQTRNRVAKMDKQLRE 299
++ + T+ E E ++ R A + + TT E LR + R+ K + QL+
Sbjct: 348 ATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKL--RESL--------KTGEV---TTSQL 346
+ + ++ + + KEV+LE + L +E+L K E T +L
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQEL 467
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQ---HKSAIQQLEEDLKQTK---RALQEQC-EITKRE 399
I + + EV + + Q+ +T + ++ L+ +L+ K L C +++
Sbjct: 468 IGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLEN 527
Query: 400 IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
EL + T + +N E++ + E+ + E E L EL+ +E L+
Sbjct: 528 KELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKR 587
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
DEV CK +K EN +++++ NK + I ++Q + + L K +++ YE
Sbjct: 588 DEVK-CKLDKSEENCNNLRKQVE----NKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK---LLDVVHRNEELSEILAKKDQE 576
V L+ + + ++ I+ Q+EI D K+ LL+ V + + +++ K +E
Sbjct: 643 VNKLELE---LESAKQKFGEIT-DTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKE 698
Query: 577 LEQQ------------DKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
++++ +K+ ++I+ R+ + + K+KE EQS A+L+ +L +
Sbjct: 699 IDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKA 758
Query: 625 IVDEVNKQIAAKADEIQEL 643
+ V KQ+ + +E ++L
Sbjct: 759 ELLSVKKQLEIEREEKEKL 777
Score = 68.9 bits (161), Expect = 6e-11
Identities = 89/459 (19%), Positives = 197/459 (42%), Gaps = 24/459 (5%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
+C E +TQ E++ S T+ ++ E L E +L ++ + ++ E
Sbjct: 352 ICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTME 411
Query: 242 IRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--- 297
+++ SE E TK EL+E + L KE L Q + + +++L
Sbjct: 412 LQKKSSELEEMTKLTNNKEVELEELKKV-LGEKETLLYENKQFEKIAEELKGTEQELIGL 470
Query: 298 ---REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
RE E + T +Q KEV + L+ L+ ++ ++L + L
Sbjct: 471 LQAREKEVHDLEIQLTAITTSEQYYSKEV------KDLKTELENEKLKNTELTSHCNKLS 524
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
E E Q+ +T++ K+ + + + KQ +R L++ + + E +L+ E ++ +
Sbjct: 525 LENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELK 584
Query: 415 NAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
+E++ K+ + E++ N E + ELQ + L+ + K+ E K
Sbjct: 585 QKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALK--KKGTAESKQLNVYEIK 642
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ 534
+ KL EL + ++ G++ ++ I++ K++E+ +++ + + + + + +
Sbjct: 643 VN---KLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIA--DEAVKLQK 697
Query: 535 ESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
E ++ + +M+ D + + SE+ K +E EQ + + + +
Sbjct: 698 EIDKRCQHKIAEMVALMEKHKHQYDKIIEERD-SELGLYKSKEQEQSSLRASLEIELSNL 756
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ 632
+ EL++V K E E+ E L+++ + + E K+
Sbjct: 757 KAELLSVKKQLEIER-EEKEKLKREAKENTATLKEKKKK 794
Score = 54.0 bits (124), Expect = 2e-06
Identities = 96/442 (21%), Positives = 190/442 (42%), Gaps = 25/442 (5%)
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
E+R+ + + + +SEN K E +H L +E ++ +T+ L + K
Sbjct: 291 ESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATK 350
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
QL E + T + + K S + E L E L+T + + Q
Sbjct: 351 TICQLTEEKE--TQMEESNKARAAHS-FVVTEFETTVCSLEELLRTEQQRLEKNEDQLKI 407
Query: 353 LQAEVLECKQQIE---KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
L E+ + ++E KLT + +++L++ L + + L E + K ELK TE E
Sbjct: 408 LTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELK-GTEQE 466
Query: 410 LQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE 468
L A E E+ I+L + ++ DL EL+ E L+ T E+T+ +
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELE--NEKLKNT--ELTSHCNK 522
Query: 469 KESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIK---NIKLNEQKVIQYEQYVRDL 523
ENK Q+ + EL N++E I + Q ++K N++ E ++ +YVR+
Sbjct: 523 LSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREE 582
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD-K 582
R C+ + + +L++++ + + ++ N+ L + + ++L + K
Sbjct: 583 LKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIK 642
Query: 583 NSRGQARVIKIREEL--INVLKNKETEQSR-ELAALQQDLEHRMRIVDE---VNKQIAAK 636
++ + + +++ I KE E + L +++E I DE + K+I +
Sbjct: 643 VNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKR 702
Query: 637 AD-EIQELFATLENKQQQIHRL 657
+I E+ A +E + Q ++
Sbjct: 703 CQHKIAEMVALMEKHKHQYDKI 724
Score = 50.8 bits (116), Expect = 2e-05
Identities = 93/436 (21%), Positives = 203/436 (46%), Gaps = 71/436 (16%)
Query: 247 SESENTKALEEMRHELDEE----RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
S+ EN++ L + +L +E + K++ + +L ES+L++ R + K ++E +
Sbjct: 94 SDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQF 153
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEV 357
++ +K+ E K++ E A + L+E+ T + +R+ +
Sbjct: 154 GNEKVS--LKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVY 211
Query: 358 LECKQQIEK-------LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTET-- 408
++ IEK L VQ +++ ++ LK+ +Q + K+EI KE+ +
Sbjct: 212 MDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLL 271
Query: 409 --ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
++ + N +++L ++E + K N +++ +LQ+ E L+ + ++
Sbjct: 272 LIQITEKENKMKDL-TFLLEESRDKVN-------QLEEKTKLQS--ENLKQSIEKQHHLT 321
Query: 467 REKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
+E E + K+ +Q+ ++ + +E+ +QI T+ + +L E+K Q E+ + AH
Sbjct: 322 KELE-DIKVSLQRSVSTQKALEED----LQIATKTI---CQLTEEKETQMEESNKARAAH 373
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+ + + + + +E++ + + L+ +NE+ +IL +E Q K+S
Sbjct: 374 SFVVTEFETTVCSL------EELLRTEQQRLE---KNEDQLKILT-----MELQKKSSE- 418
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI----QE 642
EE+ + NKE EL L++ L + ++ E NKQ A+E+ QE
Sbjct: 419 -------LEEMTKLTNNKEV----ELEELKKVLGEKETLLYE-NKQFEKIAEELKGTEQE 466
Query: 643 LFATLENKQQQIHRLE 658
L L+ +++++H LE
Sbjct: 467 LIGLLQAREKEVHDLE 482
>AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.
Length = 1635
Score = 78.6 bits (185), Expect = 7e-14
Identities = 114/499 (22%), Positives = 225/499 (45%), Gaps = 55/499 (11%)
Query: 172 LSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQD 231
L Y + L L E++++ E + + ++ +E+ L + L+ +V ++ Q
Sbjct: 784 LRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKN--ANEKTRL--ENQNLLIQVEEVSQT 839
Query: 232 VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES-------QLR 284
+ ++ + E EN K L E + EL + R + +K+ L + S ++
Sbjct: 840 CSKSEIHNEKEKCFIKEHENLKPLLEQK-ELRDRRAELILLKDSLAKSPSVKNDPLSSVK 898
Query: 285 QTRNRVAKMDKQLREAEASITSLT-GTVKMLE--DQSRQKEVQLEARARKLRESLKTGEV 341
+ ++ ++K+ +E E I + VK + D SR++ ++ LR
Sbjct: 899 ELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSA 958
Query: 342 TTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA--IQQLEEDLKQTKRALQEQCEITKRE 399
+ LIQ +S + +LE ++Q E+L V+ + A + EDL + R QCE +
Sbjct: 959 SMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSD 1018
Query: 400 IE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
E L R ET LQ + +E +I+E++++K D E E +LQ ++
Sbjct: 1019 NEDLLARIET-LQSNAKLLE---VQILEVQRAKAMVDKELEAE-----KLQKEQKI---- 1065
Query: 459 EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ 518
++ TT +E + ++ ++K + + + E++ K QT L ++ YE+
Sbjct: 1066 KEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTT-------LMNMEIADYER 1118
Query: 519 YVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELE 578
+++L N+ + N N I +DL+QEI K K E L E + ++
Sbjct: 1119 LMKEL---NQKLTN---KNNKI--EDLEQEIKIQKQK-------QETLQEEITSLQSSVQ 1163
Query: 579 Q-QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKA 637
Q ++KN++ + ++K ++EL + K ET+ A+L+ +LE + V+ Q+A
Sbjct: 1164 QYEEKNTKIKQLLVKTKKELADS-KQAETDHLILQASLKGELEASQQQVEVYKIQLAEIT 1222
Query: 638 DEIQELFATLENKQQQIHR 656
E ++ L+ +Q R
Sbjct: 1223 SEKHKIHEHLKTSAEQHQR 1241
Score = 65.3 bits (152), Expect = 7e-10
Identities = 86/420 (20%), Positives = 189/420 (45%), Gaps = 30/420 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+++++L +++ L+EM E+ E+ K + ES L + + Q E
Sbjct: 699 EQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGES-LAKINEEKCNLAFQRDE 757
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ L +K L+++S + +L++ R + ++ ++++LQ+++LE
Sbjct: 758 ---KVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLE 814
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
K EK +++++ + Q+EE + QT + + K + +KE + + + +
Sbjct: 815 MKNANEKTRLENQNLLIQVEE-VSQT--CSKSEIHNEKEKCFIKEHENLKPLLEQKELRD 871
Query: 420 LQAKIIELEKS-KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+A++I L+ S +P + + L + KE E+ CK ++E NKI
Sbjct: 872 RRAELILLKDSLAKSPSVKND-------PLSSVKELEEKIENLEKECKEKEEKINKI--- 921
Query: 479 QKLAAELLNKEEIIGKMQIQT-RELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
KL A KE + + QT +E +++++ + Q +RDL I +
Sbjct: 922 -KLVAVKAKKELDSSRKETQTVKEELESLRSEKD---QLSASMRDL------IQGAESYK 971
Query: 538 NGISYQDLQQEIMDL-KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREE 596
N + + Q E +D+ K + + HR E+L+ L + E + ++ I+ +
Sbjct: 972 NLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQS 1031
Query: 597 LINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+L+ + E R A + ++LE ++ K+ A +E++EL L+ +++Q+ +
Sbjct: 1032 NAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQK 1091
Score = 59.3 bits (137), Expect = 5e-08
Identities = 90/470 (19%), Positives = 199/470 (42%), Gaps = 32/470 (6%)
Query: 170 EHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKR--ACHERRTLIAVGEALVREVAK 227
E + + + +L LR Q E + DL R L+ V + L + AK
Sbjct: 989 ERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEV-QILEVQRAK 1047
Query: 228 LRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT- 286
D E + + ++++ + LEE++ +L +E+ ++L + +QT
Sbjct: 1048 AMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTT 1107
Query: 287 --RNRVAKMDKQLREAEASITSLTGTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEV 341
+A ++ ++E +T+ ++ LE + +QK+ L+ L+ S++ E
Sbjct: 1108 LMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEE 1167
Query: 342 TTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE 401
+++ Q + E+ + KQ + S +LE +Q + + EIT + +
Sbjct: 1168 KNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHK 1227
Query: 402 LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDE 461
+ E +T + + + Q ++ L++ + + +E ++ K +RV
Sbjct: 1228 IHEHLKTSAEQHQRTLSAYQQRVTALQE---ECRAAKAEQATVTSEFESYK--VRVH--- 1279
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN--EQKVIQYEQY 519
K++K + E + E +I +++I+ ++ N+++N E + +Q E
Sbjct: 1280 -NVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHD 1338
Query: 520 VRDLQAHNRTIAN--CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK--KDQ 575
L+ HN+ + +E+ +Q E M +K + V + +E+L +DQ
Sbjct: 1339 TL-LERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQ 1397
Query: 576 ELEQQDKNSRG----QARVIKIREELINVLKNKETEQSRELAALQQDLEH 621
Q+++ + Q ++ K+ +L LKN+ T +R + QQ L++
Sbjct: 1398 VRHLQEEHRKTVETLQQQLSKMEAQLFQ-LKNEPT--TRSPVSSQQSLKN 1444
Score = 57.6 bits (133), Expect = 1e-07
Identities = 84/423 (19%), Positives = 178/423 (42%), Gaps = 26/423 (6%)
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
ET+ V +E+ LRSE + A MR + + K + E +E QL + R
Sbjct: 938 ETQTVK-EELESLRSEKDQLSA--SMRDLIQGAESYKNLLLEYEKQSE-QLDVEKERANN 993
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
+ ++ + + + T + + + L AR L+ + K EV ++ + +
Sbjct: 994 FEHRIEDLTRQLRNSTLQCETINSDNED----LLARIETLQSNAKLLEVQILEVQRAKAM 1049
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
+ E+ K Q E+ +H + + +LEE Q ++ ++Q + T +E+EL ++ +
Sbjct: 1050 VDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKE-KKQLQKTMQELELVKKDAQQTTL 1108
Query: 413 SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR--EKE 470
I + + + EL + N + E DL E++ K+ ++E+T+ + ++
Sbjct: 1109 MNMEIADYERLMKELNQKLTNKNNKIE---DLEQEIKIQKQKQETLQEEITSLQSSVQQY 1165
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
E I+Q L K+E+ Q +T LI L + +Q ++ + +
Sbjct: 1166 EEKNTKIKQLLVK---TKKELADSKQAETDHLILQASLKGELEASQQQ----VEVYKIQL 1218
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
A + I ++ L+ + L R L E + + EQ S ++
Sbjct: 1219 AEITSEKHKI-HEHLKTSAEQHQRTLSAYQQRVTALQEEC--RAAKAEQATVTSEFESYK 1275
Query: 591 IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
+++ ++ KNK Q+ E +Q+ EH ++D++ ++ + +Q + L+
Sbjct: 1276 VRVHN-VLKQQKNKSMSQA-ETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTL 1333
Query: 651 QQQ 653
Q +
Sbjct: 1334 QSE 1336
Score = 56.4 bits (130), Expect = 3e-07
Identities = 100/491 (20%), Positives = 211/491 (42%), Gaps = 47/491 (9%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE 248
L+ Q E+A+NT +LS++ + + V + L E+ K+R E + + + + + ++
Sbjct: 103 LQKQLEEAMNTQLELSEQLKFQNNSEDNV-KKLQEEIEKIRPGFEEQILYLQKQLDATTD 161
Query: 249 SENTKALEEMRH--ELDEERTAKL--AIKEKLTTTES-QLRQTRNRVAKMDKQLREAEAS 303
E + + ++++ E + + K +++E+L ++ + + + +++ +E EA
Sbjct: 162 -EKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAE 220
Query: 304 ITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
I L + L Q E ++ + E+L+ +Q D+ +L +
Sbjct: 221 INKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQ-----DNQICSILLQENT 275
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI----ELKERTETELQDSRNAI-- 417
+ V K ++ LE+ LK+ L+ Q I K E+ LK + E + Q ++
Sbjct: 276 FVEQVVNEK--VKHLEDTLKE----LESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFH 329
Query: 418 --EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED----EVTTCKREKES 471
E+L+ KI EL +K E+ L +EL + T + EV + K + +
Sbjct: 330 EREDLEFKINELLLAKEEQGCVIEK---LKSELAGLNKQFCYTVEQHNREVQSLKEQHQK 386
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQ-TRELIKNIKLNEQK-VIQYEQYVRDLQAHNRT 529
E I + KE++ +IQ +E +N++ +Q+ ++ YE R
Sbjct: 387 E--ISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESL--------RE 436
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEILAKKDQELEQQDKNSRGQA 588
I ++ G S + QE +K + VH ++L +KD LE ++ +G+
Sbjct: 437 IMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNR-LQGEN 495
Query: 589 RVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
+ ++EL+ L+N + L R ++ E+ +I + +E + L+
Sbjct: 496 EKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLK 555
Query: 649 NKQQQIHRLEK 659
N +++ K
Sbjct: 556 NSHEEMDNFHK 566
Score = 37.1 bits (82), Expect = 0.21
Identities = 62/318 (19%), Positives = 143/318 (44%), Gaps = 22/318 (6%)
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE 379
+KE++ E R++ + E TG++ + L ++ D+L E E +QQ L ++ Q++E
Sbjct: 3 EKEIE-ELRSKPVTEG--TGDIIKA-LTERLDALLLEKAETEQQCLSLKKENIKMKQEVE 58
Query: 380 EDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
+ + + A +E + ++ E + EL R+ E +A + + + N L
Sbjct: 59 DSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELS 118
Query: 440 REIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ--- 496
++ +++ ++ ++E+ + E E + +Q++L A K+E + ++Q
Sbjct: 119 EQLKF---QNNSEDNVKKLQEEIEKIRPGFE-EQILYLQKQLDATTDEKKETVTQLQNII 174
Query: 497 -IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
++ KNI +++++Q ++ + CQ + ++ ++ +LK
Sbjct: 175 EANSQHYQKNINSLQEELLQ----LKAIHQEEVKELMCQIEASAKEHEAEINKLNELKEN 230
Query: 556 LLDVVHRNEELSEILAKKDQELEQQDK---NSRGQARVIKIREELINVLKNKETEQSREL 612
L+ +E+ I K + ELE K N+ ++ I + ++ E+ + L
Sbjct: 231 LVKQCEASEK--NIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHL 288
Query: 613 AALQQDLEHRMRIV-DEV 629
++LE + I+ DEV
Sbjct: 289 EDTLKELESQHSILKDEV 306
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 78.2 bits (184), Expect = 9e-14
Identities = 118/499 (23%), Positives = 227/499 (45%), Gaps = 55/499 (11%)
Query: 182 LCGALRELK-TQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
LC E K T + +N + A E L++ ++L EV +LR++++ ++ +
Sbjct: 713 LCNLELEGKITDLQKELNKEVE-ENEALREEVILLSELKSLPSEVERLRKEIQDKS---E 768
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ + SE + K E+ H+ E R L E++ T+ L T++ D++ +
Sbjct: 769 ELHIITSEKD--KLFSEVVHK--ESRVQGLL--EEIGKTKDDLATTQSNYKSTDQEFQNF 822
Query: 301 EASITSLTGTVKM-LEDQSR--QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ KM LE+ R Q+ V L A+K SL G + T +L + LQ +
Sbjct: 823 KTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSL--GALKT-ELSYKTQELQEKT 879
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E ++++ ++ Q K ++ + L+ +R E+ IT++ + E +T Q+ ++ +
Sbjct: 880 REVQERLNEME-QLKEQLENRDSPLQTVER---EKTLITEKLQQTLEEVKTLTQE-KDDL 934
Query: 418 EELQAKI-IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK---------- 466
++LQ + IE ++ K + ID +L+ E+L+ ++ + T K
Sbjct: 935 KQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRN 994
Query: 467 ---REKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
E E K QQK+ + K+++ K T+ L ++K NE +I+ ++ + L
Sbjct: 995 LHMEENTGETKDEFQQKMVG-IDKKQDLEAK---NTQTLTADVKDNE--IIEQQRKIFSL 1048
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI--LAKKDQELEQQD 581
+ ES + +Q DLK + + EEL + KK QE+ Q+
Sbjct: 1049 IQEKNELQQMLESV----IAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQE 1104
Query: 582 KNS--RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
KN + + + + + L V + K E+S++L QQ L + + E+ K+I +E
Sbjct: 1105 KNHAIKKEGELSRTCDRLAEV-EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKI----NE 1159
Query: 640 IQELFATLENKQQQIHRLE 658
I+ L L+NK+ + +E
Sbjct: 1160 IENLKNELKNKELTLEHME 1178
Score = 69.3 bits (162), Expect = 4e-11
Identities = 90/477 (18%), Positives = 213/477 (44%), Gaps = 26/477 (5%)
Query: 198 NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEE 257
NT+ LS+ + L+ E + E+ LR D + N+++D +LR+E E + +
Sbjct: 474 NTLDTLSEIEWNPATKLLNQ-ENIESELNSLRADYD--NLVLD-YEQLRTEKEEMELKLK 529
Query: 258 MRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED 316
+++LDE E + K++ ++ +N V + ++ E ++S ++ ED
Sbjct: 530 EKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKED 589
Query: 317 QSRQKEVQLEARARK-----LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
Q ++ + ++++ + L SL++ E Q+ Q + L+ K++ L ++
Sbjct: 590 QIKKLQEYIDSQKLENIKMDLSYSLESIE-DPKQMKQTLFDAETVALDAKRESAFLRSEN 648
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ-DSRNAIEELQAKIIELEKS 430
++++E L T + ++ ++ + ++E K++ + +L+ + ++A E+ K+ L
Sbjct: 649 LELKEKMKE-LATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEI-TKLTSLIDG 706
Query: 431 KPNPDLPTEREI-----DLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAEL 485
K DL E+ DL EL E +EV K +++ ++L E+
Sbjct: 707 KVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEV---ERLRKEI 763
Query: 486 LNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDL 545
+K E + + + +L + E +V + + + T + +S + +Q+
Sbjct: 764 QDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQ-EFQNF 822
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
+ MD + K V+ NE +++ + +E ++ D + + + + + +
Sbjct: 823 KTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREV 882
Query: 606 TEQSRELAALQQDLEHR---MRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
E+ E+ L++ LE+R ++ V+ I K + E TL ++ + +L++
Sbjct: 883 QERLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQE 939
Score = 65.3 bits (152), Expect = 7e-10
Identities = 87/444 (19%), Positives = 198/444 (44%), Gaps = 27/444 (6%)
Query: 212 RTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAKL 270
+ ++ E + +E+ L ++ + + + L++E S T+ L+E E+ E
Sbjct: 834 KMVLEENERMNQEIVNLSKEAQKFD---SSLGALKTELSYKTQELQEKTREVQERLNEME 890
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
+KE+L +S L+ + ++L++ + +LT L+ +++ +
Sbjct: 891 QLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKS 950
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
+ +++ T QL +SL+ + E ++ + S +EE+ +TK Q
Sbjct: 951 DIHDTVNMNIDTQEQLRNALESLK-QHQETINTLKSKISEEVSRNLHMEENTGETKDEFQ 1009
Query: 391 EQ-CEITKREIELKERTETELQDSR-NAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
++ I K++ + T+T D + N I E Q KI L + K E I +L
Sbjct: 1010 QKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQL 1069
Query: 449 QA-TKETLRVT---EDEVTTCKREKESENKIGIQQKLAA-----ELLNKEEIIGKMQIQT 499
+ KE + +T ++E+ E + + +I Q+K A EL + + +++ +
Sbjct: 1070 KTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKL 1129
Query: 500 RELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL-KMKLLD 558
+E + ++ +Q+++ ++ + ++Q I N + N + ++L E M+ +++L
Sbjct: 1130 KEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLK---NELKNKELTLEHMETERLELAQ 1186
Query: 559 VVHRNEELSEILAKKDQELEQQDKNSRGQARVIK--IREELINVLKNKETEQSRELAALQ 616
++ N E + + K+ + L++ K+ + ++ IRE L+ KE EL
Sbjct: 1187 KLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE-----ELKIAH 1241
Query: 617 QDLEHRMRIVDEVNKQIAAKADEI 640
L+ +DE+ + ++ K +I
Sbjct: 1242 IHLKEHQETIDELRRSVSEKTAQI 1265
Score = 65.3 bits (152), Expect = 7e-10
Identities = 87/431 (20%), Positives = 191/431 (44%), Gaps = 23/431 (5%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
DE++ + E ++ + L+E+ ++ +KE + ++ +T + L+E
Sbjct: 1435 DEMKSVAKEKDDLQRLQEVLQSESDQ------LKENIKEIVAKHLETEEELKVAHCCLKE 1488
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL-IQQRDSLQAEVL 358
E +I L + E + + QLEA KL+ ++ QL I+Q +Q V
Sbjct: 1489 QEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQENVN 1548
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL---QEQCEITKREIELKERTETELQDSRN 415
E KQ E + SA+Q +E + + L QE+ +I +E E +R + LQ R+
Sbjct: 1549 ELKQFKEHRKAK-DSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERD 1607
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
++E +I+ +K E + + T+E + E + +K + I
Sbjct: 1608 QLKENTKEIV----AKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENI 1663
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL-QAHNRTIANCQ 534
+ ++L+ E + +M+ T+E + E ++ +Q +L + R + +
Sbjct: 1664 ETENIRLTQILH--ENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQE 1721
Query: 535 ESPNGISYQDLQQEIMD-LKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV--- 590
E + QE +D L+ + + + + + L + L+ QD + + R+
Sbjct: 1722 ELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHM 1781
Query: 591 -IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+K ++E I+ L+ +E++ +L+ +Q+DLE+ + E +++ A ++ L +
Sbjct: 1782 HLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNE 1841
Query: 650 KQQQIHRLEKI 660
Q+++ +E++
Sbjct: 1842 TQKKVSEMEQL 1852
Score = 62.9 bits (146), Expect = 4e-09
Identities = 114/551 (20%), Positives = 238/551 (43%), Gaps = 42/551 (7%)
Query: 142 ETMPIENIIKYPKTNLTVNQDQTDGDILEHLSR-YNDQGFELCGALRELKTQAEDAVNTV 200
ET +E K + V + +L+ L + + + L G +RE++ +
Sbjct: 1178 ETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEEL 1237
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKL--RQDVETRNVMI-DEIRELRSESE---NTKA 254
+ T+ + ++ + A++ QD+E + + +EI L E E N K
Sbjct: 1238 KIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKK 1297
Query: 255 LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKML 314
+ E + ++E K +TT +++ R R+ + ++ +E S+T +K +
Sbjct: 1298 VSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTI 1357
Query: 315 EDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA 374
++ K QL+ R+ ++ + Q + ++ E + ++E+ + SA
Sbjct: 1358 KEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEK-DNETTKIVSEMEQFKPK-DSA 1415
Query: 375 IQQLEEDLKQTKRALQEQCE----ITKREIE---LKERTETELQDSRNAIEELQAKIIEL 427
+ ++E ++ + LQE + + K + + L+E ++E + I+E+ AK +E
Sbjct: 1416 LLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLET 1475
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
E+ + + + EL+ L E E++T +++ E+ N +Q K+ E+
Sbjct: 1476 EEELKVAHCCLKEQEETINELRV---NLSEKETEISTIQKQLEAIND-KLQNKI-QEIYE 1530
Query: 488 KEEIIGKMQI-QTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN-CQESPNGISYQDL 545
KEE + QI + +E + +K ++ + ++ +++ + N QES I
Sbjct: 1531 KEEQLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIK 1590
Query: 546 QQEIMDLKMKLLDVV--HRNEELSEILA--KKDQELEQQ-------DKNSRGQARVIKIR 594
++E M + L + E EI+A K+ QE E Q ++ + ++
Sbjct: 1591 EKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLK 1650
Query: 595 EEL----INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ-ELFATLEN 649
E+ +N L+N ETE R L ++LE MR V + + + + ++ E EN
Sbjct: 1651 EQFETQKLN-LENIETENIRLTQILHENLE-EMRSVTKERDDLRSVEETLKVERDQLKEN 1708
Query: 650 KQQQIHR-LEK 659
++ I R LEK
Sbjct: 1709 LRETITRDLEK 1719
Score = 57.2 bits (132), Expect = 2e-07
Identities = 59/262 (22%), Positives = 129/262 (49%), Gaps = 30/262 (11%)
Query: 224 EVAKLRQDVETRNVMIDE-IRELRSESENT----KALEEMRHELDEERTAKLAIKEKLTT 278
+++ +++D+E N + E I+EL++ K + E + ++ E K IK++ T
Sbjct: 1803 KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1862
Query: 279 TESQLRQTRNRVAKMDKQLREAEA------SITSLTGTVKMLEDQSRQKEVQLEARARKL 332
+ N ++ + L E ++ ++ + T+K+ DQ ++ + +AR ++
Sbjct: 1863 LSKLEIENLNLAQELHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI 1922
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
++ LKT + + + + D L +++I + T+Q I +++DL ++K LQ++
Sbjct: 1923 QQELKTARMLSKEHKETVDKL-------REKISEKTIQ----ISDIQKDLDKSKDELQKK 1971
Query: 393 C-EITKREIELKERTETELQDSRNAIEELQAKIIELEKS-KPNPDLPTERE-IDLWAELQ 449
E+ K+E++L R + ++ S I E++ +L+K +PN E + L +L
Sbjct: 1972 IQELQKKELQLL-RVKEDVNMSHKKINEME----QLKKQFEPNYLCKCEMDNFQLTKKLH 2026
Query: 450 ATKETLRVTEDEVTTCKREKES 471
+ E +R+ E +R KES
Sbjct: 2027 ESLEEIRIVAKERDELRRIKES 2048
Score = 43.6 bits (98), Expect = 0.002
Identities = 115/561 (20%), Positives = 238/561 (42%), Gaps = 49/561 (8%)
Query: 128 IASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALR 187
+A EN E+ +N+ + +T L + +DQ + E L + E+ L+
Sbjct: 1873 LAQELHENLEEMKSVMKERDNLRRVEET-LKLERDQ----LKESLQETKARDLEIQQELK 1927
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR---EVAKLRQDVETRNVMIDEIRE 244
+ +++ TV L ++ + + + + L + E+ K Q+++ + + + ++E
Sbjct: 1928 TARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKE 1987
Query: 245 -LRSESENTKALEEMRHELDEERTAKLAIKE-KLTTTESQLRQTRNRVAKMDKQLREAEA 302
+ + +E+++ + + K + +LT + + VAK +LR +
Sbjct: 1988 DVNMSHKKINEMEQLKKQFEPNYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKE 2047
Query: 303 SIT----SLTGTVKMLEDQSRQK-EVQLEARA-----RKLRESLKTGEVTTSQLIQQRDS 352
S+ T++ + + RQ +V+ E R + L ESL+ +L+++
Sbjct: 2048 SLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSE 2107
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
+ + EC + +L++ + I+ +K+ K L +I + + E + E + D
Sbjct: 2108 MD-DHYEC---LNRLSLDLEKEIE-FHRIMKKLKYVLSYVTKIKEEQHECINKFEMDFID 2162
Query: 413 SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+EL KI L++ + D+P+ DL + + + +E+ K ESE
Sbjct: 2163 EVEKQKELLIKIQHLQQ---DCDVPSRELRDL-----KLNQNMDLHIEEIL--KDFSESE 2212
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQ--IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
I+ + L N++E+ ++ + TR I+ +K QK V + +NR I
Sbjct: 2213 FP-SIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNF-FNNRII 2270
Query: 531 ANCQESP-----NGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQ--ELEQQDKN 583
A ES + ++ +Q++ LK K + + L LA Q Q +KN
Sbjct: 2271 AIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKN 2330
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD-EIQE 642
+R ++ E I L+N +++E A ++ +M+ EV I AK ++ E
Sbjct: 2331 PHVTSRATQLTTEKIRELEN-SLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHE 2389
Query: 643 LFATLENKQQQIHRL-EKIVL 662
LE ++ I L +K+ L
Sbjct: 2390 SNKCLEKTKETIQVLQDKVAL 2410
Score = 38.7 bits (86), Expect = 0.069
Identities = 34/145 (23%), Positives = 70/145 (48%), Gaps = 11/145 (7%)
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
R+ T+ + E+ + L E + + + + K+ + +L T + +AK+ ++ E+ +
Sbjct: 2336 RATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLE 2395
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLR-ESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
T+++L+D +V L A+ K E LK V I A+ E +
Sbjct: 2396 KTKETIQVLQD-----KVALGAKPYKEEIEDLKMKLVK----IDLEKMKNAKEFEKEISA 2446
Query: 365 EKLTVQH-KSAIQQLEEDLKQTKRA 388
K TV++ K I+ L E+L+++++A
Sbjct: 2447 TKATVEYQKEVIRLLRENLRRSQQA 2471
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 78.2 bits (184), Expect = 9e-14
Identities = 88/445 (19%), Positives = 201/445 (45%), Gaps = 27/445 (6%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
+V +L++++ ++ +E+++ + + + +++ EL + T LA++ KL T +Q
Sbjct: 439 KVEQLKEELSSKEAQWEELKKKAAGLQ--AEIGQVKQELSRKDTELLALQTKLETLTNQF 496
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
++ + + + L E L V L + +KE L + +++++ +
Sbjct: 497 SDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA 556
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++ +D +L+ K++ K+ V K I+ L+E L+ ++ + E K
Sbjct: 557 GEIHDLKD-----MLDVKER--KVNVLQKK-IENLQEQLRDKEKQMSSLKERVKSLQADT 608
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA-ELQATKETLRVTEDEV 462
T+T L A+ E + I L++ + + + EID + +L+ KE + + + ++
Sbjct: 609 TNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDL 668
Query: 463 TTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
+ EKE+ + K A L + +++T E+ ++ +++ ++ E ++
Sbjct: 669 S----EKEASL---LDLKEHASSLASSGLKKDSRLKTLEIA--LEQKKEECLKMESQLK- 718
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
+AH + Q L++EI K + + L EIL + + E +DK
Sbjct: 719 -KAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK 777
Query: 583 NSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ----IAAKAD 638
R +K + + + LK+KE + ++ A + ++ R +++ ++Q + K D
Sbjct: 778 KIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDD 837
Query: 639 EIQELFATLENKQQQIHRLEKIVLA 663
I+EL L + QI ++VLA
Sbjct: 838 RIEELEEAL-RESVQITAEREMVLA 861
Score = 70.5 bits (165), Expect = 2e-11
Identities = 100/470 (21%), Positives = 204/470 (43%), Gaps = 30/470 (6%)
Query: 209 HERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTA 268
HER +A E V + L + E N M+ E R E+ A + + E + +
Sbjct: 330 HERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDS 389
Query: 269 KLAIKEK-LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEA 327
K++ E+ L E +++ ++ A + + RE E +K +E R ++
Sbjct: 390 KISSMERGLRDLEEEIQMLKSNGA-LSTEEREEE---------MKQMEVY-RSHSKFMKN 438
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
+ +L+E L + E +L ++ LQAE+ + KQ++ + + A+Q E L
Sbjct: 439 KVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTE-LLALQTKLETLTNQFS 497
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIE-ELQAKIIEL-EKSKPNPDLPTEREIDLW 445
++ E+ K + KE+ LQ +A+ L+ K L +K+K D+ E+
Sbjct: 498 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA- 556
Query: 446 AELQATKETLRVTEDEVTTCKREKES-ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
E+ K+ L V E +V +++ E+ + ++ ++K + L + + + T +
Sbjct: 557 GEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Query: 505 NIK---LNEQKVIQ--YEQYVRDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLL 557
++ +++ I+ EQ RD + I N ++ + + LQ ++ + + LL
Sbjct: 617 TLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLL 676
Query: 558 DVVHRNEELSEILAKKDQELEQQD-KNSRGQARVIKIREELINVLKNK-ETEQSRELAAL 615
D+ L+ KKD L+ + + + +K+ +L + E S E++
Sbjct: 677 DLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDR 736
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN----KQQQIHRLEKIV 661
Q LE + + + + A+ D + E+ +EN K ++I LE+ V
Sbjct: 737 IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQV 786
Score = 60.1 bits (139), Expect = 3e-08
Identities = 99/503 (19%), Positives = 205/503 (40%), Gaps = 28/503 (5%)
Query: 192 QAEDAVNTVTDLS---KRACHERRTLIAVGEALVREVAKLRQDVETR-NVMIDEIRELRS 247
QA D NT+ DL K E L E +++ ++T + + + R LR
Sbjct: 145 QARD--NTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRK 202
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+ + + + ++ + +E + + + E ++++ N++ + D R E + L
Sbjct: 203 DEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAEL 262
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
T E+ ++ + E +A++L KT E ++ Q+ +L A K+ +E L
Sbjct: 263 T------EENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML 316
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
+ SA + EED ++T+R + + + E L E+ E E R EE+ +
Sbjct: 317 QSKGLSA-KATEEDHERTRRLAEAEMHVHHLE-SLLEQKEKENSMLR---EEMHRRFENA 371
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
S L T E+ +++ + + LR E+E+ K + ++ E+
Sbjct: 372 PDSAKTKALQTVIEMKD-SKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYR 430
Query: 488 KEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQ 547
K +++ +L + + E + + ++ LQA + + S LQ
Sbjct: 431 SHSKFMKNKVE--QLKEELSSKEAQWEELKKKAAGLQAEIGQVKQ-ELSRKDTELLALQT 487
Query: 548 EIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETE 607
++ L + D E L E L K EQ+ + + +++R E + NK+T+
Sbjct: 488 KLETLTNQFSDSKQHIEVLKESLTAK----EQRAAILQTEVDALRLRLEEKETMLNKKTK 543
Query: 608 QSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXX 667
Q +++A ++ + + ++ + K ++ L +EN Q+Q+ EK + +L
Sbjct: 544 QIQDMA---EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER 600
Query: 668 XXXXXXXXXXXXXKIAALEHELA 690
+ LE LA
Sbjct: 601 VKSLQADTTNTDTALTTLEEALA 623
Score = 50.8 bits (116), Expect = 2e-05
Identities = 59/267 (22%), Positives = 121/267 (45%), Gaps = 24/267 (8%)
Query: 223 REVAKLRQDVETRNVMIDEIR--ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT- 279
+++A+L + V+ +N + ++ E + ++ + LEE R D + +++ L
Sbjct: 777 KKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD 836
Query: 280 ------ESQLRQTRNRVAKMDKQLREAEASITSLTGTVK---MLEDQSRQKEVQLEARAR 330
E LR++ A+ + L + E++ T+ V+ M ++ +Q+ ++A+
Sbjct: 837 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 896
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
++SL E + L +R EVLE KQ+ + K A L E L +K+ Q
Sbjct: 897 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLE-LSSSKKKTQ 955
Query: 391 EQCEITKRE-----IELKERTETELQDSRNAIEELQAKIIELEKS--KPNPDLPTEREID 443
E+ KRE +LK++T+ ++ + E+ K ++ KP+PD + I
Sbjct: 956 EEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPD----QIIQ 1011
Query: 444 LWAELQATKETLRVTEDEVTTCKREKE 470
EL + L++ +TT +++
Sbjct: 1012 PLLELDQNRSKLKLYIGHLTTLCHDRD 1038
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 78.2 bits (184), Expect = 9e-14
Identities = 88/445 (19%), Positives = 201/445 (45%), Gaps = 27/445 (6%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
+V +L++++ ++ +E+++ + + + +++ EL + T LA++ KL T +Q
Sbjct: 439 KVEQLKEELSSKEAQWEELKKKAAGLQ--AEIGQVKQELSRKDTELLALQTKLETLTNQF 496
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
++ + + + L E L V L + +KE L + +++++ +
Sbjct: 497 SDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA 556
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++ +D +L+ K++ K+ V K I+ L+E L+ ++ + E K
Sbjct: 557 GEIHDLKD-----MLDVKER--KVNVLQKK-IENLQEQLRDKEKQMSSLKERVKSLQADT 608
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA-ELQATKETLRVTEDEV 462
T+T L A+ E + I L++ + + + EID + +L+ KE + + + ++
Sbjct: 609 TNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDL 668
Query: 463 TTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
+ EKE+ + K A L + +++T E+ ++ +++ ++ E ++
Sbjct: 669 S----EKEASL---LDLKEHASSLASSGLKKDSRLKTLEIA--LEQKKEECLKMESQLK- 718
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
+AH + Q L++EI K + + L EIL + + E +DK
Sbjct: 719 -KAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK 777
Query: 583 NSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ----IAAKAD 638
R +K + + + LK+KE + ++ A + ++ R +++ ++Q + K D
Sbjct: 778 KIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDD 837
Query: 639 EIQELFATLENKQQQIHRLEKIVLA 663
I+EL L + QI ++VLA
Sbjct: 838 RIEELEEAL-RESVQITAEREMVLA 861
Score = 70.5 bits (165), Expect = 2e-11
Identities = 100/470 (21%), Positives = 204/470 (43%), Gaps = 30/470 (6%)
Query: 209 HERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTA 268
HER +A E V + L + E N M+ E R E+ A + + E + +
Sbjct: 330 HERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDS 389
Query: 269 KLAIKEK-LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEA 327
K++ E+ L E +++ ++ A + + RE E +K +E R ++
Sbjct: 390 KISSMERGLRDLEEEIQMLKSNGA-LSTEEREEE---------MKQMEVY-RSHSKFMKN 438
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
+ +L+E L + E +L ++ LQAE+ + KQ++ + + A+Q E L
Sbjct: 439 KVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTE-LLALQTKLETLTNQFS 497
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIE-ELQAKIIEL-EKSKPNPDLPTEREIDLW 445
++ E+ K + KE+ LQ +A+ L+ K L +K+K D+ E+
Sbjct: 498 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA- 556
Query: 446 AELQATKETLRVTEDEVTTCKREKES-ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
E+ K+ L V E +V +++ E+ + ++ ++K + L + + + T +
Sbjct: 557 GEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Query: 505 NIK---LNEQKVIQ--YEQYVRDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLL 557
++ +++ I+ EQ RD + I N ++ + + LQ ++ + + LL
Sbjct: 617 TLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLL 676
Query: 558 DVVHRNEELSEILAKKDQELEQQD-KNSRGQARVIKIREELINVLKNK-ETEQSRELAAL 615
D+ L+ KKD L+ + + + +K+ +L + E S E++
Sbjct: 677 DLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDR 736
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN----KQQQIHRLEKIV 661
Q LE + + + + A+ D + E+ +EN K ++I LE+ V
Sbjct: 737 IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQV 786
Score = 60.1 bits (139), Expect = 3e-08
Identities = 99/503 (19%), Positives = 205/503 (40%), Gaps = 28/503 (5%)
Query: 192 QAEDAVNTVTDLS---KRACHERRTLIAVGEALVREVAKLRQDVETR-NVMIDEIRELRS 247
QA D NT+ DL K E L E +++ ++T + + + R LR
Sbjct: 145 QARD--NTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRK 202
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+ + + + ++ + +E + + + E ++++ N++ + D R E + L
Sbjct: 203 DEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAEL 262
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
T E+ ++ + E +A++L KT E ++ Q+ +L A K+ +E L
Sbjct: 263 T------EENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML 316
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
+ SA + EED ++T+R + + + E L E+ E E R EE+ +
Sbjct: 317 QSKGLSA-KATEEDHERTRRLAEAEMHVHHLE-SLLEQKEKENSMLR---EEMHRRFENA 371
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
S L T E+ +++ + + LR E+E+ K + ++ E+
Sbjct: 372 PDSAKTKALQTVIEMKD-SKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYR 430
Query: 488 KEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQ 547
K +++ +L + + E + + ++ LQA + + S LQ
Sbjct: 431 SHSKFMKNKVE--QLKEELSSKEAQWEELKKKAAGLQAEIGQVKQ-ELSRKDTELLALQT 487
Query: 548 EIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETE 607
++ L + D E L E L K EQ+ + + +++R E + NK+T+
Sbjct: 488 KLETLTNQFSDSKQHIEVLKESLTAK----EQRAAILQTEVDALRLRLEEKETMLNKKTK 543
Query: 608 QSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXX 667
Q +++A ++ + + ++ + K ++ L +EN Q+Q+ EK + +L
Sbjct: 544 QIQDMA---EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER 600
Query: 668 XXXXXXXXXXXXXKIAALEHELA 690
+ LE LA
Sbjct: 601 VKSLQADTTNTDTALTTLEEALA 623
Score = 50.8 bits (116), Expect = 2e-05
Identities = 59/267 (22%), Positives = 121/267 (45%), Gaps = 24/267 (8%)
Query: 223 REVAKLRQDVETRNVMIDEIR--ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT- 279
+++A+L + V+ +N + ++ E + ++ + LEE R D + +++ L
Sbjct: 777 KKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD 836
Query: 280 ------ESQLRQTRNRVAKMDKQLREAEASITSLTGTVK---MLEDQSRQKEVQLEARAR 330
E LR++ A+ + L + E++ T+ V+ M ++ +Q+ ++A+
Sbjct: 837 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 896
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
++SL E + L +R EVLE KQ+ + K A L E L +K+ Q
Sbjct: 897 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLE-LSSSKKKTQ 955
Query: 391 EQCEITKRE-----IELKERTETELQDSRNAIEELQAKIIELEKS--KPNPDLPTEREID 443
E+ KRE +LK++T+ ++ + E+ K ++ KP+PD + I
Sbjct: 956 EEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPD----QIIQ 1011
Query: 444 LWAELQATKETLRVTEDEVTTCKREKE 470
EL + L++ +TT +++
Sbjct: 1012 PLLELDQNRSKLKLYIGHLTTLCHDRD 1038
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 78.2 bits (184), Expect = 9e-14
Identities = 88/445 (19%), Positives = 201/445 (45%), Gaps = 27/445 (6%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
+V +L++++ ++ +E+++ + + + +++ EL + T LA++ KL T +Q
Sbjct: 439 KVEQLKEELSSKEAQWEELKKKAAGLQ--AEIGQVKQELSRKDTELLALQTKLETLTNQF 496
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
++ + + + L E L V L + +KE L + +++++ +
Sbjct: 497 SDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA 556
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++ +D +L+ K++ K+ V K I+ L+E L+ ++ + E K
Sbjct: 557 GEIHDLKD-----MLDVKER--KVNVLQKK-IENLQEQLRDKEKQMSSLKERVKSLQADT 608
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA-ELQATKETLRVTEDEV 462
T+T L A+ E + I L++ + + + EID + +L+ KE + + + ++
Sbjct: 609 TNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDL 668
Query: 463 TTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
+ EKE+ + K A L + +++T E+ ++ +++ ++ E ++
Sbjct: 669 S----EKEASL---LDLKEHASSLASSGLKKDSRLKTLEIA--LEQKKEECLKMESQLK- 718
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
+AH + Q L++EI K + + L EIL + + E +DK
Sbjct: 719 -KAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK 777
Query: 583 NSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ----IAAKAD 638
R +K + + + LK+KE + ++ A + ++ R +++ ++Q + K D
Sbjct: 778 KIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDD 837
Query: 639 EIQELFATLENKQQQIHRLEKIVLA 663
I+EL L + QI ++VLA
Sbjct: 838 RIEELEEAL-RESVQITAEREMVLA 861
Score = 70.5 bits (165), Expect = 2e-11
Identities = 100/470 (21%), Positives = 204/470 (43%), Gaps = 30/470 (6%)
Query: 209 HERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTA 268
HER +A E V + L + E N M+ E R E+ A + + E + +
Sbjct: 330 HERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDS 389
Query: 269 KLAIKEK-LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEA 327
K++ E+ L E +++ ++ A + + RE E +K +E R ++
Sbjct: 390 KISSMERGLRDLEEEIQMLKSNGA-LSTEEREEE---------MKQMEVY-RSHSKFMKN 438
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
+ +L+E L + E +L ++ LQAE+ + KQ++ + + A+Q E L
Sbjct: 439 KVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTE-LLALQTKLETLTNQFS 497
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIE-ELQAKIIEL-EKSKPNPDLPTEREIDLW 445
++ E+ K + KE+ LQ +A+ L+ K L +K+K D+ E+
Sbjct: 498 DSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA- 556
Query: 446 AELQATKETLRVTEDEVTTCKREKES-ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
E+ K+ L V E +V +++ E+ + ++ ++K + L + + + T +
Sbjct: 557 GEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Query: 505 NIK---LNEQKVIQ--YEQYVRDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLL 557
++ +++ I+ EQ RD + I N ++ + + LQ ++ + + LL
Sbjct: 617 TLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLL 676
Query: 558 DVVHRNEELSEILAKKDQELEQQD-KNSRGQARVIKIREELINVLKNK-ETEQSRELAAL 615
D+ L+ KKD L+ + + + +K+ +L + E S E++
Sbjct: 677 DLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDR 736
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN----KQQQIHRLEKIV 661
Q LE + + + + A+ D + E+ +EN K ++I LE+ V
Sbjct: 737 IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQV 786
Score = 60.1 bits (139), Expect = 3e-08
Identities = 99/503 (19%), Positives = 205/503 (40%), Gaps = 28/503 (5%)
Query: 192 QAEDAVNTVTDLS---KRACHERRTLIAVGEALVREVAKLRQDVETR-NVMIDEIRELRS 247
QA D NT+ DL K E L E +++ ++T + + + R LR
Sbjct: 145 QARD--NTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRK 202
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+ + + + ++ + +E + + + E ++++ N++ + D R E + L
Sbjct: 203 DEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAEL 262
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
T E+ ++ + E +A++L KT E ++ Q+ +L A K+ +E L
Sbjct: 263 T------EENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEML 316
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
+ SA + EED ++T+R + + + E L E+ E E R EE+ +
Sbjct: 317 QSKGLSA-KATEEDHERTRRLAEAEMHVHHLE-SLLEQKEKENSMLR---EEMHRRFENA 371
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
S L T E+ +++ + + LR E+E+ K + ++ E+
Sbjct: 372 PDSAKTKALQTVIEMKD-SKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYR 430
Query: 488 KEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQ 547
K +++ +L + + E + + ++ LQA + + S LQ
Sbjct: 431 SHSKFMKNKVE--QLKEELSSKEAQWEELKKKAAGLQAEIGQVKQ-ELSRKDTELLALQT 487
Query: 548 EIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETE 607
++ L + D E L E L K EQ+ + + +++R E + NK+T+
Sbjct: 488 KLETLTNQFSDSKQHIEVLKESLTAK----EQRAAILQTEVDALRLRLEEKETMLNKKTK 543
Query: 608 QSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXX 667
Q +++A ++ + + ++ + K ++ L +EN Q+Q+ EK + +L
Sbjct: 544 QIQDMA---EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER 600
Query: 668 XXXXXXXXXXXXXKIAALEHELA 690
+ LE LA
Sbjct: 601 VKSLQADTTNTDTALTTLEEALA 623
Score = 50.8 bits (116), Expect = 2e-05
Identities = 59/267 (22%), Positives = 121/267 (45%), Gaps = 24/267 (8%)
Query: 223 REVAKLRQDVETRNVMIDEIR--ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT- 279
+++A+L + V+ +N + ++ E + ++ + LEE R D + +++ L
Sbjct: 777 KKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD 836
Query: 280 ------ESQLRQTRNRVAKMDKQLREAEASITSLTGTVK---MLEDQSRQKEVQLEARAR 330
E LR++ A+ + L + E++ T+ V+ M ++ +Q+ ++A+
Sbjct: 837 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 896
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
++SL E + L +R EVLE KQ+ + K A L E L +K+ Q
Sbjct: 897 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLE-LSSSKKKTQ 955
Query: 391 EQCEITKRE-----IELKERTETELQDSRNAIEELQAKIIELEKS--KPNPDLPTEREID 443
E+ KRE +LK++T+ ++ + E+ K ++ KP+PD + I
Sbjct: 956 EEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPD----QIIQ 1011
Query: 444 LWAELQATKETLRVTEDEVTTCKREKE 470
EL + L++ +TT +++
Sbjct: 1012 PLLELDQNRSKLKLYIGHLTTLCHDRD 1038
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 77.8 bits (183), Expect = 1e-13
Identities = 101/485 (20%), Positives = 215/485 (44%), Gaps = 29/485 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 906 ERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 965
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQ--L 297
++ + + +EN K L E LD E AKL+ KEK E+ + + A+ DK L
Sbjct: 966 KVEKEKHATENKVKNLTEEMAGLD-ETIAKLS-KEKKALQETHQQTLDDLQAEEDKVNIL 1023
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + +T + + L ++
Sbjct: 1024 TKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKL 1083
Query: 358 LECKQQIEKL--TVQHKSAIQ-QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ + +I L ++ + A++ QL++ +K+ + ++E E + E + + E + D
Sbjct: 1084 EKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLS 1143
Query: 415 NAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESEN 473
+EE+ ++ E + +L +RE + + +L+ E + + + R+K +++
Sbjct: 1144 RELEEISERLEEAGGATSAQVELNKKREAE-FQKLRRDLEEATLQHEAMVAALRKKHADS 1202
Query: 474 KIGIQQKL-----AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNR 528
+ +++ + L KE+ +++++T +L N + + E+ R L+
Sbjct: 1203 MAELGEQIDNLQRVKQKLEKEK--SELKMETDDLSSNAEAISKAKGNLEKMCRSLED--- 1257
Query: 529 TIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQA 588
Q S ++ Q+ I DL + + E S L +KD + Q ++ +
Sbjct: 1258 -----QVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQAST 1312
Query: 589 RVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
+ I EEL + L+ +ET+ LA Q H ++ E ++ E+Q +
Sbjct: 1313 QQI---EELKHQLE-EETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKAN 1368
Query: 649 NKQQQ 653
++ Q
Sbjct: 1369 SEVAQ 1373
Score = 75.8 bits (178), Expect = 5e-13
Identities = 83/437 (18%), Positives = 194/437 (44%), Gaps = 32/437 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E + K++L +E++ ++ ++ + K+ +
Sbjct: 838 KIKPLLKSAETEKEMATMKEEFQKT-------KDELAKSEAKRKELEEKMVTLLKEKNDL 890
Query: 301 EASITSLTGTVKMLEDQSRQ---KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + S ++ E++ Q ++QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 891 QLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDEC 950
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + +
Sbjct: 951 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTL 1010
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1011 DDLQAEEDKVNILTKAKTK----LEQQVD---DLEGSLEQEKKLRMDLERAKRKLEGDLK 1063
Query: 475 IGIQQKLAAE--LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
+ + + E +E + K + + LI I+ + IQ ++ +++LQA +
Sbjct: 1064 LAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGE 1123
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-----SEILAKKDQELEQQDKNSRGQ 587
E+ S +++ DL +L ++ R EE +++ K +E E Q K R
Sbjct: 1124 EIEAERA-SRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQ-KLRRDL 1181
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATL 647
E ++ L+ K + +A L + +++ R+ ++ K+ + E +L +
Sbjct: 1182 EEATLQHEAMVAALRKKHAD---SMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNA 1238
Query: 648 ENKQQQIHRLEKIVLAL 664
E + LEK+ +L
Sbjct: 1239 EAISKAKGNLEKMCRSL 1255
Score = 69.7 bits (163), Expect = 3e-11
Identities = 114/559 (20%), Positives = 222/559 (39%), Gaps = 32/559 (5%)
Query: 118 QEVAQLYRDAIA-SSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYN 176
+ +A+L ++ A T + L+ L NI+ KT L D +G + +
Sbjct: 990 ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRM 1049
Query: 177 D---QGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA---KLRQ 230
D +L G L+ + D N L ++ + + + + E A +L++
Sbjct: 1050 DLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQK 1109
Query: 231 DVETRNVMIDEI-RELRSESENTKALEEMRHELDEE-RTAKLAIKEKLTTTESQLRQTRN 288
++ I+E+ E+ +E + E+ R +L E ++E T +Q+ +
Sbjct: 1110 KIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKK 1169
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQ 348
R A+ K R+ E + V L + +L + L+ + E S+L
Sbjct: 1170 REAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKM 1229
Query: 349 QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTET 408
+ D L + + I K + + LE+ + + K +EQ + + R +T
Sbjct: 1230 ETDDLSSNA----EAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQT 1285
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKETLRVTEDEVTTC-- 465
E + ++E A + +L +SK E + L E +A + C
Sbjct: 1286 EAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDL 1345
Query: 466 ---KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
+ E+E E K +Q+ L+ N E + + +T + + +L E K + Q +++
Sbjct: 1346 LREQYEEEQEGKAELQRALSKA--NSEVAQWRTKYETDAIQRTEELEEAKK-KLAQRLQE 1402
Query: 523 LQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD 581
+ H + A C + Q LQ E+ DL +LDV R+ L KK + ++
Sbjct: 1403 AEEHVEAVNAKCASLEK--TKQRLQNEVEDL---MLDV-ERSNAACAALDKKQRNFDKV- 1455
Query: 582 KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
S + + + + EL + + S EL ++ E + ++ + ++ EI
Sbjct: 1456 -LSEWKQKYEETQAEL-EASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEIS 1513
Query: 642 ELFATLENKQQQIHRLEKI 660
+L + +QIH LEKI
Sbjct: 1514 DLTEQIAEGGKQIHELEKI 1532
Score = 67.7 bits (158), Expect = 1e-10
Identities = 103/533 (19%), Positives = 232/533 (43%), Gaps = 58/533 (10%)
Query: 138 ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALR----ELKTQA 193
E +D ++ ++ K+ L + D + E +S+ ++C +L ELKT+
Sbjct: 1208 EQIDNLQRVKQKLEKEKSELKMETDDLSSNA-EAISKAKGNLEKMCRSLEDQVSELKTKE 1266
Query: 194 EDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK 253
E+ + DL+ + L E + + ++ ++ ++ ++ RS+ +T+
Sbjct: 1267 EEQQRLINDLTAQRAR-----------LQTEAGEYSRQLDEKDALVSQLS--RSKQASTQ 1313
Query: 254 ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
+EE++H+L+EE AK A+ L ++ R + + + E + +++ V
Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ 1373
Query: 314 ----LEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTV 369
E + Q+ +LE +KL + L+ E + + SL+ + ++E L +
Sbjct: 1374 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLML 1433
Query: 370 ---QHKSAIQQLEEDLKQTKRALQE---QCEITKREIELKER----TETELQDSRNAIEE 419
+ +A L++ + + L E + E T+ E+E ++ TEL +N EE
Sbjct: 1434 DVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
++ L + N ++EI E Q + ++ E E + E+E +
Sbjct: 1494 SLDQLETLRRENKN----LQQEISDLTE-QIAEGGKQIHELEKIKKQVEQEKCEIQAALE 1548
Query: 480 KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNG 539
+ A L ++E I ++Q++ ++ + ++K+ + ++ + L+ ++ + +S
Sbjct: 1549 EAEASLEHEEGKILRIQLELNQVKSEV---DRKIAEKDEEIDQLKRNHTRVVETMQSTLD 1605
Query: 540 ISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELIN 599
+ + + + +K K+ +L+E+ E++ N R A ++
Sbjct: 1606 AEIRS-RNDALRVKKKM------EGDLNEM------EIQLNHAN-RLAAESLRNYRNTQG 1651
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+LK + L Q+DL+ ++ IV+ + A EI+EL+ATLE ++
Sbjct: 1652 ILKETQLHLDDALRG-QEDLKEQLAIVERRANLLQA---EIEELWATLEQTER 1700
Score = 61.3 bits (142), Expect = 1e-08
Identities = 98/471 (20%), Positives = 198/471 (42%), Gaps = 57/471 (12%)
Query: 160 NQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGE 219
N Q D+ E ++ Q EL ++++ + + + + HE ++ +
Sbjct: 1507 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1566
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE---RTAKLAIKEK- 275
L + +++ + + ++ ID+++ +T+ +E M+ LD E R L +K+K
Sbjct: 1567 ELNQVKSEVDRKIAEKDEEIDQLKR-----NHTRVVETMQSTLDAEIRSRNDALRVKKKM 1621
Query: 276 ---LTTTESQLRQTRNRVAKMDKQLREAEASITS----LTGTVKMLEDQSRQKEVQLEAR 328
L E QL A+ + R + + L ++ ED Q + +E R
Sbjct: 1622 EGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI-VERR 1680
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
A L+ ++ T Q + R + E+L+ ++++ L Q+ S I TK+
Sbjct: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN--------TKKK 1732
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
L+ +L+ E +Q+SRNA E+ + I + ++E D A L
Sbjct: 1733 LENDVS------QLQSEVEEVIQESRNAEEKAKKAITDAAMMAEE----LKKEQDTSAHL 1782
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
+ K+ L T K+ ++++ ++LA L ++ I K++ + REL ++
Sbjct: 1783 ERMKKNLEQT---------VKDLQHRLDEAEQLA--LKGGKKQIQKLEARVRELEGEVE- 1830
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANC-----QESPNGISYQDLQQEIMDLKMKLLDVVHRN 563
NEQK + + V+ L+ H R + ++ N + QDL ++
Sbjct: 1831 NEQK--RNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEA 1888
Query: 564 EELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
EE S K ++L+ + + + +A I E +N L+ K E +++A
Sbjct: 1889 EEQSNANLSKFRKLQHELEEAEERAH---IAESQVNKLRVKSREVHTKISA 1936
>AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FHA)
phosphopeptide binding domain 1 protein.
Length = 692
Score = 77.8 bits (183), Expect = 1e-13
Identities = 94/434 (21%), Positives = 206/434 (47%), Gaps = 38/434 (8%)
Query: 235 RNVMIDEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTESQLRQTRNRVAKM 293
++++ +++RE +E E L E R E +E+ AK+ + E+ E + Q RNR +
Sbjct: 2 QSLLQEKLREHLAEKEK---LNEERLEQEEKLKAKIRQLTEEKAALEEYITQERNRAKET 58
Query: 294 DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSL 353
++ R+ + SL L Q + + +++E+L+ E T Q +++R +
Sbjct: 59 LEEERKRMQELESL------LAQQKKALAKSITQEKNRVKEALEE-EQTRVQELEERLAR 111
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
Q E+ E EK K A+++ ++ ++ + L +Q K E+ELKE+ E L
Sbjct: 112 QKEISESNIAYEKRKA--KEAMEKEKKKVQDLENRLTKQ----KEELELKEQKEDVL--- 162
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESEN 473
N + + A + E +K+K L E L +L T L T+ ++ + +
Sbjct: 163 NNKLSDALAMVEETQKTKATESLKAE---SLALKLNETLAELETTKTKMIMVEERLILQQ 219
Query: 474 KI--GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
K+ +Q + ++ EE I + + Q ++ + I E+K+ + Q+ + ++ T+
Sbjct: 220 KMVKALQDEQESQRHGFEEEIMEYKEQIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLK 279
Query: 532 NCQESPNGISYQD-LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
+ +P QD L + + K + H + ++LA + + L QQ+ +
Sbjct: 280 DNDPAPKEERPQDPLVAPMTESSAKDMAYEHL---IDDLLAAQKEILSQQEV-------I 329
Query: 591 IKIREELINVLKNKETEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+K+R++L ++ ++ EL Q+ +LE + +V + +K+++ +++ ++ + +E
Sbjct: 330 MKLRKDLTEA-HSRMSDLRGELNEKQKMELEQNVVLVQQQSKELSVLKEKMAQMSSLVEK 388
Query: 650 KQQQIHRLEKIVLA 663
K +++ LE+ + A
Sbjct: 389 KDRELKALEEALRA 402
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 77.8 bits (183), Expect = 1e-13
Identities = 91/437 (20%), Positives = 194/437 (44%), Gaps = 26/437 (5%)
Query: 233 ETRNVMIDEIRELRSESENTK-ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
E R + ++ RS S+ K + +++ EL + T LA++ KL T +Q ++ +
Sbjct: 417 EEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 476
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
+ + L E L V L + +KE L + +++++ + ++ +D
Sbjct: 477 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKD 536
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
+L+ K++ K+ V K I+ L+E L+ ++ + E K T+T L
Sbjct: 537 -----MLDVKER--KVNVLQKK-IENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 588
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA-ELQATKETLRVTEDEVTTCKREKE 470
A+ E + I L++ + + + EID + +L+ KE + + + +++ EKE
Sbjct: 589 TLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLS----EKE 644
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ + K A L + +++T E+ ++ +++ ++ E ++ +AH +
Sbjct: 645 ASL---LDLKEHASSLASSGLKKDSRLKTLEIA--LEQKKEECLKMESQLK--KAHEAAL 697
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
Q L++EI K + + L EIL + + E +DK R
Sbjct: 698 EARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQ 757
Query: 591 IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ----IAAKADEIQELFAT 646
+K + + + LK+KE + ++ A + ++ R +++ ++Q + K D I+EL
Sbjct: 758 VKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEA 817
Query: 647 LENKQQQIHRLEKIVLA 663
L + QI ++VLA
Sbjct: 818 L-RESVQITAEREMVLA 833
Score = 66.9 bits (156), Expect = 2e-10
Identities = 94/434 (21%), Positives = 198/434 (45%), Gaps = 37/434 (8%)
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ E EN+ EEM + A + K K T +++ ++ ++ M++ LR+ E I
Sbjct: 352 QKEKENSMLREEMHRRFEN---APDSAKTKALQTVIEMKDSK--ISSMERGLRDLEEEIQ 406
Query: 306 SL--TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
L G + E + K++++ K ++ K G+V Q + ++D+ E+L + +
Sbjct: 407 MLKSNGALSTEEREEEMKQMEVYRSHSKFMKN-KIGQV--KQELSRKDT---ELLALQTK 460
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL----KERTETELQDSRNAI-- 417
+E LT Q + Q +E LK++ A +++ I + E++ E ET L I
Sbjct: 461 LETLTNQFSDSKQHIEV-LKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQD 519
Query: 418 --EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR-----EKE 470
EE + E+ K D+ + L +++ +E LR E ++++ K + +
Sbjct: 520 MAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQAD 579
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ N L L KE I +++ Q R+ ++ + ++++ Y++ ++DL+ ++
Sbjct: 580 TTNTDTALTTLEEALAEKERTIERLKEQ-RD--RDEREKQEEIDNYKKDLKDLK-EKVSL 635
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQE---LEQQDKNSRGQ 587
S S DL++ L L R + L L +K +E +E Q K +
Sbjct: 636 LQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEA 695
Query: 588 ARVIKIREELINVLKNKETEQSR---ELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
A + E+ + +++ E E +R E + Q +++ + I+ EV + K +I EL
Sbjct: 696 ALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELE 755
Query: 645 ATLENKQQQIHRLE 658
++++ +++ L+
Sbjct: 756 RQVKDQNKKVANLK 769
Score = 50.8 bits (116), Expect = 2e-05
Identities = 59/267 (22%), Positives = 121/267 (45%), Gaps = 24/267 (8%)
Query: 223 REVAKLRQDVETRNVMIDEIR--ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT- 279
+++A+L + V+ +N + ++ E + ++ + LEE R D + +++ L
Sbjct: 749 KKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD 808
Query: 280 ------ESQLRQTRNRVAKMDKQLREAEASITSLTGTVK---MLEDQSRQKEVQLEARAR 330
E LR++ A+ + L + E++ T+ V+ M ++ +Q+ ++A+
Sbjct: 809 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS 868
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
++SL E + L +R EVLE KQ+ + K A L E L +K+ Q
Sbjct: 869 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLE-LSSSKKKTQ 927
Query: 391 EQCEITKRE-----IELKERTETELQDSRNAIEELQAKIIELEKS--KPNPDLPTEREID 443
E+ KRE +LK++T+ ++ + E+ K ++ KP+PD + I
Sbjct: 928 EEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPD----QIIQ 983
Query: 444 LWAELQATKETLRVTEDEVTTCKREKE 470
EL + L++ +TT +++
Sbjct: 984 PLLELDQNRSKLKLYIGHLTTLCHDRD 1010
Score = 49.6 bits (113), Expect = 4e-05
Identities = 80/450 (17%), Positives = 199/450 (44%), Gaps = 26/450 (5%)
Query: 255 LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEAS-ITSLTGTVKM 313
L+E+ E D R + KL+++ + ++ + K ++ LR+ EAS IT ++
Sbjct: 158 LKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRV 217
Query: 314 LEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR-DSLQAEVLECKQQIEKLTVQHK 372
++++++ ++ ++A +LR ++ + + AE+ E + ++L +H+
Sbjct: 218 VQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTE--ENFQRLHAEHE 275
Query: 373 SAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKP 432
++L L++T ++ + E K+ + ++ + +L + + + L AK E + +
Sbjct: 276 RQAKELFL-LRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS-KGLSAKATEEDHERT 333
Query: 433 NPDLPTEREIDLWAEL--QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE 490
E + L Q KE + E+ + +S +Q + K+
Sbjct: 334 RRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEM----KDS 389
Query: 491 IIGKMQIQTRELIKNIKLNEQK----VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
I M+ R+L + I++ + + E+ ++ ++ + R+ + ++ G Q+L
Sbjct: 390 KISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVY-RSHSKFMKNKIGQVKQELS 448
Query: 547 Q---EIMDLKMKLLDVVHR---NEELSEILAKKDQELEQQDKNSRGQARVIKIREELINV 600
+ E++ L+ KL + ++ +++ E+L + EQ+ + + +++R E
Sbjct: 449 RKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKET 508
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
+ NK+T+Q +++A ++ + + ++ + K ++ L +EN Q+Q+ EK
Sbjct: 509 MLNKKTKQIQDMA---EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQ 565
Query: 661 VLALXXXXXXXXXXXXXXXXKIAALEHELA 690
+ +L + LE LA
Sbjct: 566 MSSLKERVKSLQADTTNTDTALTTLEEALA 595
>AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A
protein.
Length = 1016
Score = 77.4 bits (182), Expect = 2e-13
Identities = 115/520 (22%), Positives = 238/520 (45%), Gaps = 60/520 (11%)
Query: 127 AIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGAL 186
++ S E + DE++P + P+ ++ + T+ + E R GF A
Sbjct: 135 SVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTE-EGTELSQRLVRSGF----AG 189
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR-EVAKLRQDVETRNVMIDEIREL 245
E+ + E+ + ++ + A + L A+ E + E AK+ Q +M + R+
Sbjct: 190 TEIDPENEELMLNISSRLQAAVE--KLLEAISETSSQLEHAKVTQT----ELMRESFRQK 243
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA----- 300
+ +E+ K EE+R L EE A+ + +L+ E + + ++Q++E
Sbjct: 244 QEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIID 303
Query: 301 --EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT--GEVTTSQLIQQRDSLQAE 356
E + + ++ LE + +Q + + E +R+ +E++K G V QL+Q+ + L E
Sbjct: 304 RLEQELLCASNRLQELEAEQQQIQEERELLSRQ-KEAMKAEAGPVE-QQLLQETEKLMKE 361
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
LE + Q EK+ + ++ LE D++ E R IEL++ TEL D R
Sbjct: 362 KLEVQCQAEKVRDDLQKQVKALEIDVE----------EQVSRFIELEQEKNTELMDLRQQ 411
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLRVTEDEVTTCKREKESENKI 475
+ L+ ++ ++ K + E E D++ E+Q ++ L+V + + SE++
Sbjct: 412 NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVP------RFQPISEHQT 465
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
++LA L K + ++ + +L ++I+ +++ + E VR+L+ A
Sbjct: 466 REVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSA---- 521
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKNSRGQARVIK 592
D Q++ D K V ELS ++ A++D ++ + + + ++ +
Sbjct: 522 --------DTFQKVED--RKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQ 571
Query: 593 IREELINVLKNKETEQ-SRELAALQQDLEHRMRIVDEVNK 631
REEL N KN+E +Q +L +++ R++ +++ NK
Sbjct: 572 FREELEN--KNEEVQQLHMQLEIQKKESTTRLQELEQENK 609
Score = 36.7 bits (81), Expect = 0.28
Identities = 67/333 (20%), Positives = 145/333 (43%), Gaps = 32/333 (9%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
+R+L+TQ E +S + C +R + E L + KL+Q++ I + +
Sbjct: 681 IRDLETQIECL------MSDQECVKRNREEEI-EQLNEVIEKLQQELAN----IGQKTSM 729
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ S + +A + ++H+LD KLA+++++ T ++ +N + + + ++ + +
Sbjct: 730 NAHSLSEEA-DSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELF 788
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
SL + +E E + L + EV ++ D+L++ LE +
Sbjct: 789 SLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTE-----DALKS--LENQTYFR 841
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTETELQDSRNAIEELQAKI 424
K +I LE L Q + + + E+T+ ++K+ E + E LQ KI
Sbjct: 842 SFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQE----QGQFETEMLQKKI 897
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQ----K 480
+ L+K + + +L+A +E + +D T E E N + Q +
Sbjct: 898 VNLQKI---VEEKVAAALVSQIQLEAVQEYAKFCQDN-QTISSEPERTNIQNLNQLREDE 953
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV 513
L +++ I +++ Q E+ ++ L +++V
Sbjct: 954 LGSDISALTLRISELESQVVEMHTSLILEKEQV 986
>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
Length = 3908
Score = 77.4 bits (182), Expect = 2e-13
Identities = 115/520 (22%), Positives = 238/520 (45%), Gaps = 60/520 (11%)
Query: 127 AIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGAL 186
++ S E + DE++P + P+ ++ + T+ + E R GF A
Sbjct: 1779 SVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTE-EGTELSQRLVRSGF----AG 1833
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR-EVAKLRQDVETRNVMIDEIREL 245
E+ + E+ + ++ + A + L A+ E + E AK+ Q +M + R+
Sbjct: 1834 TEIDPENEELMLNISSRLQAAVE--KLLEAISETSSQLEHAKVTQT----ELMRESFRQK 1887
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA----- 300
+ +E+ K EE+R L EE A+ + +L+ E + + ++Q++E
Sbjct: 1888 QEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIID 1947
Query: 301 --EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT--GEVTTSQLIQQRDSLQAE 356
E + + ++ LE + +Q + + E +R+ +E++K G V QL+Q+ + L E
Sbjct: 1948 RLEQELLCASNRLQELEAEQQQIQEERELLSRQ-KEAMKAEAGPVE-QQLLQETEKLMKE 2005
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
LE + Q EK+ + ++ LE D++ E R IEL++ TEL D R
Sbjct: 2006 KLEVQCQAEKVRDDLQKQVKALEIDVE----------EQVSRFIELEQEKNTELMDLRQQ 2055
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLRVTEDEVTTCKREKESENKI 475
+ L+ ++ ++ K + E E D++ E+Q ++ L+V + + SE++
Sbjct: 2056 NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVP------RFQPISEHQT 2109
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
++LA L K + ++ + +L ++I+ +++ + E VR+L+ A
Sbjct: 2110 REVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSA---- 2165
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKNSRGQARVIK 592
D Q++ D K V ELS ++ A++D ++ + + + ++ +
Sbjct: 2166 --------DTFQKVED--RKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQ 2215
Query: 593 IREELINVLKNKETEQ-SRELAALQQDLEHRMRIVDEVNK 631
REEL N KN+E +Q +L +++ R++ +++ NK
Sbjct: 2216 FREELEN--KNEEVQQLHMQLEIQKKESTTRLQELEQENK 2253
Score = 70.5 bits (165), Expect = 2e-11
Identities = 96/487 (19%), Positives = 217/487 (44%), Gaps = 61/487 (12%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALV---REVAKLRQDVETRNVMIDEIRELR 246
K + ++ + +L+ + E + + + + L + + +L++ + +N EI+ ++
Sbjct: 321 KEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN---QEIKNMK 377
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ--TRNRVAKMDKQLREAEASI 304
E N+K E E ++ + +K +SQ + + ++L + A +
Sbjct: 378 LELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAEL 437
Query: 305 TSLTGT--VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS---------- 352
+ G V+M ++ RQ Q+E + + ++ + S + D
Sbjct: 438 DEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINE 497
Query: 353 LQAEVLECKQQIEKLT------VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
L ++ + Q EKL ++ K A+Q+ EDL + +EQ + ++ I +E
Sbjct: 498 LNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESK 557
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E S + +E+L+A+I+ +S+ +L E E+ + K L + E E
Sbjct: 558 LNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNY------KIKLEMLEKEKNAVL 611
Query: 467 REKESENKIGIQQKLAAELL-NKEEIIGKMQ--IQTRELIKNIKLNEQKVIQYEQYVRDL 523
++ +E++ ++L +LL + EE + K++ ++ I KL + I Y+Q + L
Sbjct: 612 -DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGL 670
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
Q ++ Q+I ++ + +++ + +L ++K ++L+Q N
Sbjct: 671 Q------------------NEMSQKIETMQFEKDNLITKQNQLILEISKL-KDLQQSLVN 711
Query: 584 SRGQARVIKIRE--ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
S+ + ++I E + I +L+ +E E+ L+Q+++ + + KQ+ K +++Q
Sbjct: 712 SKSEEMTLQINELQKEIEILRQEEKEKG----TLEQEVQELQLKTELLEKQMKEKENDLQ 767
Query: 642 ELFATLE 648
E FA LE
Sbjct: 768 EKFAQLE 774
Score = 62.5 bits (145), Expect = 5e-09
Identities = 91/418 (21%), Positives = 187/418 (44%), Gaps = 31/418 (7%)
Query: 255 LEEMRHELDEER-TAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
+EE+ EL+E R T ++L E+ ++Q + ++ L++A
Sbjct: 171 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLE 230
Query: 314 LEDQSRQKEVQLEA--RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
L +QS++ ++Q + + LR S T T + L+Q + ++L +QQ+E+
Sbjct: 231 LTEQSQKLQIQFQQLQASETLRNS--THSSTAADLLQAKQ----QILTHQQQLEEQDHLL 284
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELK--ERTETELQDSRNAIEELQAKIIELEK 429
+ Q+ +ED LQE+ ++ + E + K + E+Q+ IEEL KIIE EK
Sbjct: 285 ED-YQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEK 343
Query: 430 S--KPNPDLPTEREI--DLWAELQATKETLRVTEDEVTTCK-REKESENKIGIQQKLAAE 484
+ L T ++ +L ++ + ++ + E+T K +E++S +I E
Sbjct: 344 KTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEE 403
Query: 485 LLNKEEIIGKMQ---IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
L + + + +Q E KL + + E Y + + + + Q
Sbjct: 404 LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIR-QHMAQMEE 462
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEIL--AKKDQELEQQDKNSRGQARVIKIREELIN 599
+ + M+ ++ + NE+ +++ A + ++ QD NS+ + K++EEL
Sbjct: 463 MKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE----KLKEELGL 518
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA---AKADEIQELFATLENKQQQI 654
+L+ K Q R+L L ++L + + IA +K +E + +T+E+ + +I
Sbjct: 519 ILEEKCALQ-RQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEI 575
Score = 59.3 bits (137), Expect = 5e-08
Identities = 83/413 (20%), Positives = 187/413 (45%), Gaps = 30/413 (7%)
Query: 174 RYNDQGFELCGALREL-KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
R +QG E A+ L K ++ + L + + TL E+ L ++
Sbjct: 3068 RIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNI 3127
Query: 233 ETRNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
+ + + E++ EL S + L+E +L E+ +K +L T+ +L T
Sbjct: 3128 QQKQSQMLEMQVELSSMKDRATELQE---QLSSEKMVVAELKSELAQTKLELETTLKAQH 3184
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
K K+L + T V +L D ++ ++R+L+ +L+ + + ++RD
Sbjct: 3185 KHLKELEAFRLEVKDKTDEVHLLNDTLASEQ----KKSRELQWALEKEKAKLGRS-EERD 3239
Query: 352 SLQAEVLECKQQIEKL-TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL 410
+ E L+ + +K +Q ++Q ++ L ++++ ++ Q + ++ ++ EL
Sbjct: 3240 KEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLEL 3299
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
Q +E + +I E+ + +RE +L A+LQ++ T + + + + KE
Sbjct: 3300 QV---LLESEKVRIREMSST-------LDRERELHAQLQSSDGTGQ-SRPPLPSEDLLKE 3348
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ ++ + ELLN+ E +QTR+ ++ + +K +Q EQ +A+
Sbjct: 3349 LQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQ-----EANTEGQ 3403
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK-KDQELEQQDK 582
E + + +DLQ+++ + + ++ + + L I+ + + QELE+++K
Sbjct: 3404 KKMHELQSKV--EDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEK 3454
Score = 53.2 bits (122), Expect = 3e-06
Identities = 100/442 (22%), Positives = 204/442 (46%), Gaps = 40/442 (9%)
Query: 181 ELCGALRELKTQAEDAV-NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMI 239
+L G L+E Q + N +L+ ER++ + + L+ V +L++ +
Sbjct: 357 KLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQ-LMGTVEELQKRNHKDSQFE 415
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTE-SQLRQTRNR-VAKMDKQ 296
+I + R E E + LE++R ELDE ++ +K++L +Q+ + + R +M+
Sbjct: 416 TDIVQ-RMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENA 474
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLE---ARARKLRESLKTGEVTTSQLIQQRDSL 353
LR + ++IT +K++ + ++L+ ++ KL+E L L +Q + L
Sbjct: 475 LR-SYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDL 533
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
E+ ++QI++ + I + E L + ++L E K EI + EL+
Sbjct: 534 VEELSFSREQIQRA----RQTIAEQESKLNEAHKSLST-VEDLKAEIVSASESRKELELK 588
Query: 414 RNA-IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT-EDEVTTCKREKES 471
A + + K+ LEK K N L E AEL+ + L + E+E++ K + E
Sbjct: 589 HEAEVTNYKIKLEMLEKEK-NAVLDRMAESQE-AELERLRTQLLFSHEEELSKLKEDLEI 646
Query: 472 ENKIGIQQ-KLAAELLNKEEIIG-----KMQIQTRELIKNIKLNEQKVIQYE-QYVRDLQ 524
E++I I++ K + K++I G +I+T + K+ + +Q + E ++DLQ
Sbjct: 647 EHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ 706
Query: 525 -------AHNRTIA-NCQESPNGISYQD------LQQEIMDLKMKLLDVVHRNEELSEIL 570
+ T+ N + I Q+ L+QE+ +L++K + + +E L
Sbjct: 707 QSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDL 766
Query: 571 AKKDQELEQQDKNSRGQARVIK 592
+K +LE ++ + + + ++
Sbjct: 767 QEKFAQLEAENSILKDEKKTLE 788
Score = 51.6 bits (118), Expect = 9e-06
Identities = 85/425 (20%), Positives = 185/425 (43%), Gaps = 33/425 (7%)
Query: 72 DRQAVLEVFQNLKSLYERLNNEGISACGE--GFLP-QELILFNVADWTAQEVAQLYRDAI 128
DR+++L Q +L+ ++N I+ E P QEL+ +N+ +Q L
Sbjct: 3087 DRRSLLSEIQ---ALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQ---MLEMQVE 3140
Query: 129 ASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRE 188
SS + A EL ++ + ++ K+ L QT ++ L + EL
Sbjct: 3141 LSSMKDRATELQEQLSSEKMVVAELKSELA----QTKLELETTLKAQHKHLKEL----EA 3192
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR-ELRS 247
+ + +D + V L+ E++ + AL +E AKL + E +++++ L S
Sbjct: 3193 FRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLES 3252
Query: 248 ESENTKALE---EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+ + L E + +L E K+ + L ++QL + + R ++ L + I
Sbjct: 3253 QKQRNLQLNLLLEQQKQLLNESQQKIESQRMLY--DAQLSEEQGRNLELQVLLESEKVRI 3310
Query: 305 TSLTGTVKMLEDQSRQKEVQLEAR--ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
++ T+ D+ R+ QL++ + R L + ++ +L +Q + + ++E
Sbjct: 3311 REMSSTL----DRERELHAQLQSSDGTGQSRPPLPSEDLL-KELQKQLEEKHSRIVELLN 3365
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
+ EK + QQ+E+D + ++ LQ + E + +++++D + +EE +
Sbjct: 3366 ETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQ 3425
Query: 423 KI--IELEKSKPNPDLPTEREIDL-WAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
++ ++LE + + ++ +L E + ++ L +E TT + +QQ
Sbjct: 3426 QVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQ 3485
Query: 480 KLAAE 484
K+ E
Sbjct: 3486 KIEGE 3490
Score = 50.0 bits (114), Expect = 3e-05
Identities = 79/383 (20%), Positives = 165/383 (43%), Gaps = 24/383 (6%)
Query: 108 ILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKT--NLTVN-QDQT 164
+L +A+ E+ +L + S E L L E + IE+ I K NL ++ + Q
Sbjct: 610 VLDRMAESQEAELERLRTQLLFSH--EEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQI 667
Query: 165 DGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVG-EALVR 223
DG E + FE + + + Q ++ + DL + + + + + L +
Sbjct: 668 DGLQNEMSQKIETMQFEKDNLITK-QNQLILEISKLKDLQQSLVNSKSEEMTLQINELQK 726
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENT-KALEEMRHELDEE----RTAKLAIKEKLTT 278
E+ LRQ+ + + + E++EL+ ++E K ++E ++L E+ +K++ T
Sbjct: 727 EIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKT 786
Query: 279 TESQLR-----QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQS-RQKEVQLEARARKL 332
E L+ R+ +D +++ S+ + + E++ +Q+ +QL K
Sbjct: 787 LEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQ 846
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE----KLTVQHKSAIQQLEEDLKQTKRA 388
R + E Q+ A +L+ K +E K +++KS ++ L E+L +R
Sbjct: 847 RNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL-HLQRI 905
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE-LEKSKPNPDLPTEREIDLWAE 447
++ + + E + +E+ +++E LE +K ++R DL +
Sbjct: 906 NPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQ 965
Query: 448 LQATKETLRVTEDEVTTCKREKE 470
L+ + +EV + K EKE
Sbjct: 966 LKPKPGEISFLNEEVKSLKPEKE 988
Score = 44.0 bits (99), Expect = 0.002
Identities = 85/465 (18%), Positives = 202/465 (43%), Gaps = 39/465 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
+R+L+TQ E +S + C +R + E L + KL+Q++ I + +
Sbjct: 2325 IRDLETQIECL------MSDQECVKRNREEEI-EQLNEVIEKLQQELAN----IGQKTSM 2373
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ S + +A + ++H+LD KLA+++++ T ++ +N + + + ++ + +
Sbjct: 2374 NAHSLSEEA-DSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELF 2432
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
SL + +E E + L + EV ++ D+L++ LE + +
Sbjct: 2433 SLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTE-----DALKS--LENQTYFK 2485
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTETELQDSRNAIEELQAKI 424
K +I LE L Q + + + E+T+ ++K+ E + E LQ KI
Sbjct: 2486 SFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQE----QGQFETEMLQKKI 2541
Query: 425 IELEK---SKPNPDLPTEREIDL---WAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+ L+K K L ++ +++ +A+ +T+ + + E+++G
Sbjct: 2542 VNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSD 2601
Query: 479 -QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
L + E + +M + +++ E+ V++ E+ + +LQ + + ++
Sbjct: 2602 ISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQ---KLLEGNEKKQ 2658
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEE---LSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ Q++ LK ++ H NEE +E+ A + + + + + + + + K++
Sbjct: 2659 REKEKKRSPQDVEVLK-TTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQ 2717
Query: 595 EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
EEL+ V + T ++L+ ++ L + + K+ + E
Sbjct: 2718 EELL-VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 2761
Score = 42.3 bits (95), Expect = 0.006
Identities = 67/317 (21%), Positives = 145/317 (45%), Gaps = 30/317 (9%)
Query: 357 VLEC-KQQIEKLTVQHKSAIQQLEE-DLKQTKRALQE-QCEITKREIELKERTETELQDS 413
+L C +Q+I++ V++++A++ L++ D + +Q ++ R+I LK E+E + S
Sbjct: 3061 LLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESE-KPS 3119
Query: 414 RNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+ +E +Q K ++ + + +R +L +L + K + + E+ K E E+
Sbjct: 3120 QELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETT 3179
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
K Q K EL +++ ++ + L + ++ R+LQ
Sbjct: 3180 LKA--QHKHLKEL-------EAFRLEVKDKTDEVHLLNDTLASEQKKSRELQ----WALE 3226
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV-- 590
+++ G S + ++E+ DLK L RN +L+ +L ++ Q L + + Q +
Sbjct: 3227 KEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYD 3286
Query: 591 IKIREEL-----INVLKNKETEQSRELAAL---QQDLEHRMRIVDEV--NKQIAAKADEI 640
++ EE + VL E + RE+++ +++L +++ D ++ D +
Sbjct: 3287 AQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLL 3346
Query: 641 QELFATLENKQQQIHRL 657
+EL LE K +I L
Sbjct: 3347 KELQKQLEEKHSRIVEL 3363
Score = 41.5 bits (93), Expect = 0.010
Identities = 63/282 (22%), Positives = 124/282 (43%), Gaps = 26/282 (9%)
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
+E + V HKS + L+ DL++TK+ ++ E+ L+++ + Q+ I LQ +
Sbjct: 1314 LEDIDVNHKSKLSSLQ-DLEKTKQLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKR 1372
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATK---ETLRVTEDEVTTCKRE---KESENKIGI 477
+ + +S P LP + + ++ Q T ++ D E KE N + +
Sbjct: 1373 LQAVSESTVPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEETNIVKL 1432
Query: 478 QQKLAAELLNKE--EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+K E L +E ++I M I + + +++ K E QAH A CQ+
Sbjct: 1433 LEKQYQEQLEEEVAKVIVSMSIAFAQQTELSRISGGK----ENTASSKQAH----AVCQQ 1484
Query: 536 SPNGISYQDLQQEIMDLK-MKLLDVVHRNE--ELSEILAKKDQE--LEQQDKNSRGQAR- 589
+ + L Q+ + + + +DV + E LS+ L + +E L D + +++
Sbjct: 1485 EQHYFNEMKLSQDQIGFQTFETVDVKFKEEFKPLSKELGEHGKEILLSNSDPHDIPESKD 1544
Query: 590 -VIKIREELINVLKNKETEQS--RELAALQQDLEHRMRIVDE 628
V+ I EE+ + K QS E++ D ++ + +E
Sbjct: 1545 CVLTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEE 1586
Score = 39.9 bits (89), Expect = 0.030
Identities = 78/419 (18%), Positives = 176/419 (42%), Gaps = 36/419 (8%)
Query: 263 DEERTAKL-AIKEKLTTTESQLRQTRNRV-AKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
DEER KL A K KL + Q+ + +K K+ R+ +S ++ + DQS+
Sbjct: 3 DEERQKKLEAGKAKLAQFRQRKAQSDGQSPSKKQKKKRKTSSSKHDVSAHHDLNIDQSQC 62
Query: 321 KEVQLEARAR---------KLRESLKTGEVTTSQL---IQQRDSLQAEVLECKQQIE--K 366
E+ + + R + +L +GE+T+ + ++ + +C ++
Sbjct: 63 NEMYINSSQRVESTVIPESTIMRTLHSGEITSHEQGFSVELESEISTTADDCSSEVNGCS 122
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQ-CEITKREIELKERTETELQDSRNAIEELQAKII 425
++ L E+ + EQ + + +E+ E +EL ++ IEEL ++
Sbjct: 123 FVMRTGKPTNLLREEEFGVDDSYSEQGAQDSPTHLEMME---SELAGKQHEIEELNRELE 179
Query: 426 ELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAEL 485
E+ + L +E + A ++ + + +REK+ + ++ ++
Sbjct: 180 EMRVTYGTEGLQQLQEFE--AAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQK 237
Query: 486 LNKEEIIGKMQIQTRELIKNIKLNEQK--VIQYEQYV----RDLQAHNRTIANCQESPNG 539
L I Q+Q E ++N + ++Q +Q + + L+ + + + Q+
Sbjct: 238 LQ----IQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKED 293
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ Q LQ++I +M+ D N EI K+ E K + + ++++++L
Sbjct: 294 FTMQISFLQEKIKVYEMEQ-DKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKL 352
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
K Q + + Q+ ++ + + K+ ++EI++L T+E Q++ H+
Sbjct: 353 TTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE-RQSSEEIKQLMGTVEELQKRNHK 410
>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
Length = 3911
Score = 77.4 bits (182), Expect = 2e-13
Identities = 115/520 (22%), Positives = 238/520 (45%), Gaps = 60/520 (11%)
Query: 127 AIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGAL 186
++ S E + DE++P + P+ ++ + T+ + E R GF A
Sbjct: 1790 SVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTE-EGTELSQRLVRSGF----AG 1844
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR-EVAKLRQDVETRNVMIDEIREL 245
E+ + E+ + ++ + A + L A+ E + E AK+ Q +M + R+
Sbjct: 1845 TEIDPENEELMLNISSRLQAAVE--KLLEAISETSSQLEHAKVTQT----ELMRESFRQK 1898
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA----- 300
+ +E+ K EE+R L EE A+ + +L+ E + + ++Q++E
Sbjct: 1899 QEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIID 1958
Query: 301 --EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT--GEVTTSQLIQQRDSLQAE 356
E + + ++ LE + +Q + + E +R+ +E++K G V QL+Q+ + L E
Sbjct: 1959 RLEQELLCASNRLQELEAEQQQIQEERELLSRQ-KEAMKAEAGPVE-QQLLQETEKLMKE 2016
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
LE + Q EK+ + ++ LE D++ E R IEL++ TEL D R
Sbjct: 2017 KLEVQCQAEKVRDDLQKQVKALEIDVE----------EQVSRFIELEQEKNTELMDLRQQ 2066
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLRVTEDEVTTCKREKESENKI 475
+ L+ ++ ++ K + E E D++ E+Q ++ L+V + + SE++
Sbjct: 2067 NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVP------RFQPISEHQT 2120
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
++LA L K + ++ + +L ++I+ +++ + E VR+L+ A
Sbjct: 2121 REVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSA---- 2176
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELEQQDKNSRGQARVIK 592
D Q++ D K V ELS ++ A++D ++ + + + ++ +
Sbjct: 2177 --------DTFQKVED--RKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQ 2226
Query: 593 IREELINVLKNKETEQ-SRELAALQQDLEHRMRIVDEVNK 631
REEL N KN+E +Q +L +++ R++ +++ NK
Sbjct: 2227 FREELEN--KNEEVQQLHMQLEIQKKESTTRLQELEQENK 2264
Score = 70.5 bits (165), Expect = 2e-11
Identities = 96/487 (19%), Positives = 217/487 (44%), Gaps = 61/487 (12%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALV---REVAKLRQDVETRNVMIDEIRELR 246
K + ++ + +L+ + E + + + + L + + +L++ + +N EI+ ++
Sbjct: 333 KEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN---QEIKNMK 389
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ--TRNRVAKMDKQLREAEASI 304
E N+K E E ++ + +K +SQ + + ++L + A +
Sbjct: 390 LELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAEL 449
Query: 305 TSLTGT--VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS---------- 352
+ G V+M ++ RQ Q+E + + ++ + S + D
Sbjct: 450 DEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINE 509
Query: 353 LQAEVLECKQQIEKLT------VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
L ++ + Q EKL ++ K A+Q+ EDL + +EQ + ++ I +E
Sbjct: 510 LNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESK 569
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E S + +E+L+A+I+ +S+ +L E E+ + K L + E E
Sbjct: 570 LNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNY------KIKLEMLEKEKNAVL 623
Query: 467 REKESENKIGIQQKLAAELL-NKEEIIGKMQ--IQTRELIKNIKLNEQKVIQYEQYVRDL 523
++ +E++ ++L +LL + EE + K++ ++ I KL + I Y+Q + L
Sbjct: 624 -DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGL 682
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
Q ++ Q+I ++ + +++ + +L ++K ++L+Q N
Sbjct: 683 Q------------------NEMSQKIETMQFEKDNLITKQNQLILEISKL-KDLQQSLVN 723
Query: 584 SRGQARVIKIRE--ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
S+ + ++I E + I +L+ +E E+ L+Q+++ + + KQ+ K +++Q
Sbjct: 724 SKSEEMTLQINELQKEIEILRQEEKEKG----TLEQEVQELQLKTELLEKQMKEKENDLQ 779
Query: 642 ELFATLE 648
E FA LE
Sbjct: 780 EKFAQLE 786
Score = 62.5 bits (145), Expect = 5e-09
Identities = 91/418 (21%), Positives = 187/418 (44%), Gaps = 31/418 (7%)
Query: 255 LEEMRHELDEER-TAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
+EE+ EL+E R T ++L E+ ++Q + ++ L++A
Sbjct: 183 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLE 242
Query: 314 LEDQSRQKEVQLEA--RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
L +QS++ ++Q + + LR S T T + L+Q + ++L +QQ+E+
Sbjct: 243 LTEQSQKLQIQFQQLQASETLRNS--THSSTAADLLQAKQ----QILTHQQQLEEQDHLL 296
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELK--ERTETELQDSRNAIEELQAKIIELEK 429
+ Q+ +ED LQE+ ++ + E + K + E+Q+ IEEL KIIE EK
Sbjct: 297 ED-YQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEK 355
Query: 430 S--KPNPDLPTEREI--DLWAELQATKETLRVTEDEVTTCK-REKESENKIGIQQKLAAE 484
+ L T ++ +L ++ + ++ + E+T K +E++S +I E
Sbjct: 356 KTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEE 415
Query: 485 LLNKEEIIGKMQ---IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
L + + + +Q E KL + + E Y + + + + Q
Sbjct: 416 LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIR-QHMAQMEE 474
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEIL--AKKDQELEQQDKNSRGQARVIKIREELIN 599
+ + M+ ++ + NE+ +++ A + ++ QD NS+ + K++EEL
Sbjct: 475 MKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE----KLKEELGL 530
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA---AKADEIQELFATLENKQQQI 654
+L+ K Q R+L L ++L + + IA +K +E + +T+E+ + +I
Sbjct: 531 ILEEKCALQ-RQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEI 587
Score = 59.3 bits (137), Expect = 5e-08
Identities = 83/413 (20%), Positives = 187/413 (45%), Gaps = 30/413 (7%)
Query: 174 RYNDQGFELCGALREL-KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
R +QG E A+ L K ++ + L + + TL E+ L ++
Sbjct: 3071 RIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNI 3130
Query: 233 ETRNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
+ + + E++ EL S + L+E +L E+ +K +L T+ +L T
Sbjct: 3131 QQKQSQMLEMQVELSSMKDRATELQE---QLSSEKMVVAELKSELAQTKLELETTLKAQH 3187
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
K K+L + T V +L D ++ ++R+L+ +L+ + + ++RD
Sbjct: 3188 KHLKELEAFRLEVKDKTDEVHLLNDTLASEQ----KKSRELQWALEKEKAKLGRS-EERD 3242
Query: 352 SLQAEVLECKQQIEKL-TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL 410
+ E L+ + +K +Q ++Q ++ L ++++ ++ Q + ++ ++ EL
Sbjct: 3243 KEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLEL 3302
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
Q +E + +I E+ + +RE +L A+LQ++ T + + + + KE
Sbjct: 3303 QV---LLESEKVRIREMSST-------LDRERELHAQLQSSDGTGQ-SRPPLPSEDLLKE 3351
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ ++ + ELLN+ E +QTR+ ++ + +K +Q EQ +A+
Sbjct: 3352 LQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQ-----EANTEGQ 3406
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK-KDQELEQQDK 582
E + + +DLQ+++ + + ++ + + L I+ + + QELE+++K
Sbjct: 3407 KKMHELQSKV--EDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEK 3457
Score = 53.2 bits (122), Expect = 3e-06
Identities = 100/442 (22%), Positives = 204/442 (46%), Gaps = 40/442 (9%)
Query: 181 ELCGALRELKTQAEDAV-NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMI 239
+L G L+E Q + N +L+ ER++ + + L+ V +L++ +
Sbjct: 369 KLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQ-LMGTVEELQKRNHKDSQFE 427
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTE-SQLRQTRNR-VAKMDKQ 296
+I + R E E + LE++R ELDE ++ +K++L +Q+ + + R +M+
Sbjct: 428 TDIVQ-RMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENA 486
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLE---ARARKLRESLKTGEVTTSQLIQQRDSL 353
LR + ++IT +K++ + ++L+ ++ KL+E L L +Q + L
Sbjct: 487 LR-SYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDL 545
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
E+ ++QI++ + I + E L + ++L E K EI + EL+
Sbjct: 546 VEELSFSREQIQRA----RQTIAEQESKLNEAHKSLST-VEDLKAEIVSASESRKELELK 600
Query: 414 RNA-IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT-EDEVTTCKREKES 471
A + + K+ LEK K N L E AEL+ + L + E+E++ K + E
Sbjct: 601 HEAEVTNYKIKLEMLEKEK-NAVLDRMAESQE-AELERLRTQLLFSHEEELSKLKEDLEI 658
Query: 472 ENKIGIQQ-KLAAELLNKEEIIG-----KMQIQTRELIKNIKLNEQKVIQYE-QYVRDLQ 524
E++I I++ K + K++I G +I+T + K+ + +Q + E ++DLQ
Sbjct: 659 EHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ 718
Query: 525 -------AHNRTIA-NCQESPNGISYQD------LQQEIMDLKMKLLDVVHRNEELSEIL 570
+ T+ N + I Q+ L+QE+ +L++K + + +E L
Sbjct: 719 QSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDL 778
Query: 571 AKKDQELEQQDKNSRGQARVIK 592
+K +LE ++ + + + ++
Sbjct: 779 QEKFAQLEAENSILKDEKKTLE 800
Score = 51.6 bits (118), Expect = 9e-06
Identities = 85/425 (20%), Positives = 185/425 (43%), Gaps = 33/425 (7%)
Query: 72 DRQAVLEVFQNLKSLYERLNNEGISACGE--GFLP-QELILFNVADWTAQEVAQLYRDAI 128
DR+++L Q +L+ ++N I+ E P QEL+ +N+ +Q L
Sbjct: 3090 DRRSLLSEIQ---ALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQ---MLEMQVE 3143
Query: 129 ASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRE 188
SS + A EL ++ + ++ K+ L QT ++ L + EL
Sbjct: 3144 LSSMKDRATELQEQLSSEKMVVAELKSELA----QTKLELETTLKAQHKHLKEL----EA 3195
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR-ELRS 247
+ + +D + V L+ E++ + AL +E AKL + E +++++ L S
Sbjct: 3196 FRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLES 3255
Query: 248 ESENTKALE---EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+ + L E + +L E K+ + L ++QL + + R ++ L + I
Sbjct: 3256 QKQRNLQLNLLLEQQKQLLNESQQKIESQRMLY--DAQLSEEQGRNLELQVLLESEKVRI 3313
Query: 305 TSLTGTVKMLEDQSRQKEVQLEAR--ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
++ T+ D+ R+ QL++ + R L + ++ +L +Q + + ++E
Sbjct: 3314 REMSSTL----DRERELHAQLQSSDGTGQSRPPLPSEDLL-KELQKQLEEKHSRIVELLN 3368
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
+ EK + QQ+E+D + ++ LQ + E + +++++D + +EE +
Sbjct: 3369 ETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQ 3428
Query: 423 KI--IELEKSKPNPDLPTEREIDL-WAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
++ ++LE + + ++ +L E + ++ L +E TT + +QQ
Sbjct: 3429 QVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQ 3488
Query: 480 KLAAE 484
K+ E
Sbjct: 3489 KIEGE 3493
Score = 44.0 bits (99), Expect = 0.002
Identities = 85/465 (18%), Positives = 202/465 (43%), Gaps = 39/465 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
+R+L+TQ E +S + C +R + E L + KL+Q++ I + +
Sbjct: 2336 IRDLETQIECL------MSDQECVKRNREEEI-EQLNEVIEKLQQELAN----IGQKTSM 2384
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ S + +A + ++H+LD KLA+++++ T ++ +N + + + ++ + +
Sbjct: 2385 NAHSLSEEA-DSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELF 2443
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
SL + +E E + L + EV ++ D+L++ LE + +
Sbjct: 2444 SLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTE-----DALKS--LENQTYFK 2496
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTETELQDSRNAIEELQAKI 424
K +I LE L Q + + + E+T+ ++K+ E + E LQ KI
Sbjct: 2497 SFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQE----QGQFETEMLQKKI 2552
Query: 425 IELEK---SKPNPDLPTEREIDL---WAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+ L+K K L ++ +++ +A+ +T+ + + E+++G
Sbjct: 2553 VNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSD 2612
Query: 479 -QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
L + E + +M + +++ E+ V++ E+ + +LQ + + ++
Sbjct: 2613 ISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQ---KLLEGNEKKQ 2669
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEE---LSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ Q++ LK ++ H NEE +E+ A + + + + + + + + K++
Sbjct: 2670 REKEKKRSPQDVEVLK-TTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQ 2728
Query: 595 EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
EEL+ V + T ++L+ ++ L + + K+ + E
Sbjct: 2729 EELL-VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 2772
Score = 42.3 bits (95), Expect = 0.006
Identities = 67/317 (21%), Positives = 145/317 (45%), Gaps = 30/317 (9%)
Query: 357 VLEC-KQQIEKLTVQHKSAIQQLEE-DLKQTKRALQE-QCEITKREIELKERTETELQDS 413
+L C +Q+I++ V++++A++ L++ D + +Q ++ R+I LK E+E + S
Sbjct: 3064 LLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESE-KPS 3122
Query: 414 RNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+ +E +Q K ++ + + +R +L +L + K + + E+ K E E+
Sbjct: 3123 QELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETT 3182
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
K Q K EL +++ ++ + L + ++ R+LQ
Sbjct: 3183 LKA--QHKHLKEL-------EAFRLEVKDKTDEVHLLNDTLASEQKKSRELQ----WALE 3229
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV-- 590
+++ G S + ++E+ DLK L RN +L+ +L ++ Q L + + Q +
Sbjct: 3230 KEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYD 3289
Query: 591 IKIREEL-----INVLKNKETEQSRELAAL---QQDLEHRMRIVDEV--NKQIAAKADEI 640
++ EE + VL E + RE+++ +++L +++ D ++ D +
Sbjct: 3290 AQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLL 3349
Query: 641 QELFATLENKQQQIHRL 657
+EL LE K +I L
Sbjct: 3350 KELQKQLEEKHSRIVEL 3366
Score = 37.1 bits (82), Expect = 0.21
Identities = 74/432 (17%), Positives = 180/432 (41%), Gaps = 35/432 (8%)
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+ E K LE + +++E A L +++ + + + +K K+ R+ +S +
Sbjct: 3 DEERQKKLEAGKAKIEELSLAFL-VRQLAQFRQRKAQSDGQSPSKKQKKKRKTSSSKHDV 61
Query: 308 TGTVKMLEDQSRQKEVQLEARAR---------KLRESLKTGEVTTSQL---IQQRDSLQA 355
+ + DQS+ E+ + + R + +L +GE+T+ + ++ +
Sbjct: 62 SAHHDLNIDQSQCNEMYINSSQRVESTVIPESTIMRTLHSGEITSHEQGFSVELESEIST 121
Query: 356 EVLECKQQIE--KLTVQHKSAIQQLEEDLKQTKRALQEQ-CEITKREIELKERTETELQD 412
+C ++ ++ L E+ + EQ + + +E+ E +EL
Sbjct: 122 TADDCSSEVNGCSFVMRTGKPTNLLREEEFGVDDSYSEQGAQDSPTHLEMME---SELAG 178
Query: 413 SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
++ IEEL ++ E+ + L +E + A ++ + + +REK+
Sbjct: 179 KQHEIEELNRELEEMRVTYGTEGLQQLQEFE--AAIKQRDGIITQLTANLQQARREKDET 236
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQK--VIQYEQYV----RDLQAH 526
+ ++ ++ L I Q+Q E ++N + ++Q +Q + + L+
Sbjct: 237 MREFLELTEQSQKLQ----IQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQ 292
Query: 527 NRTIANCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNS 584
+ + + Q+ + Q LQ++I +M+ D N EI K+ E K
Sbjct: 293 DHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQ-DKKVENSNKEEIQEKETIIEELNTKII 351
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
+ + ++++++L K Q + + Q+ ++ + + K+ ++EI++L
Sbjct: 352 EEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE-RQSSEEIKQLM 410
Query: 645 ATLENKQQQIHR 656
T+E Q++ H+
Sbjct: 411 GTVEELQKRNHK 422
Score = 36.7 bits (81), Expect = 0.28
Identities = 108/571 (18%), Positives = 240/571 (42%), Gaps = 37/571 (6%)
Query: 117 AQEVAQLYRDAIASSTPENALELLDETMPIENI-IKYP--KTNLTVNQDQTDGDILEHLS 173
+QE ++ D+I S + ++ E E + EN +K + N + + + E
Sbjct: 810 SQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNF 869
Query: 174 RYNDQGF-ELCGALRELKTQAEDAVNT--VTDLSK-RACHERRTLIAVGEALVREVAKLR 229
N Q E L ++K ED+ N + SK +A +E L + V+ + +
Sbjct: 870 EVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 929
Query: 230 QDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNR 289
+ +T + E E+ E K E+ +L+ + KL + ++L+ QL+Q
Sbjct: 930 DEDKT---FVAETLEMGEVVE--KDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGE 984
Query: 290 VAKMD---KQLREAEASITSLTGTVKMLEDQSRQKEVQ-LEARARKLRESLKT-----GE 340
++ ++ K L++ + ++ ++++ + +R + VQ + + L + + T E
Sbjct: 985 ISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAE 1044
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED-----LKQTKRALQEQCEI 395
+ S++ + ++E K E +TV +S +QL D K++ + E
Sbjct: 1045 GSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSEN 1104
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
K + EL ++E D R +E Q + L S + E + L + KE L
Sbjct: 1105 DKLQKELNV-LKSEQNDLRLQMEA-QRICLSLVYSTHVDQVREYMENEKDKALCSLKEEL 1162
Query: 456 RVTEDE-VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI 514
++E + ++ + E + Q+ E +IGK+Q E V+
Sbjct: 1163 IFAQEEKIKELQKIHQLELQTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVL 1222
Query: 515 --QYEQYVR-DLQAHNRTIANCQESPN-GISYQDLQQEIMDLKMKLLDVVHR-NEELSEI 569
Y ++ ++ A ++ + S N QD + E+ D + + ++++ EE +++
Sbjct: 1223 GEYYTPALKCEVNAEDKENSGDYISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKL 1282
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ-DLEHRMRIVDE 628
L + + + + + G ++ EE + + + ++ L+ D+ H+ ++
Sbjct: 1283 LVLQTRLSKIWGQQTDGMK--LEFGEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSL 1340
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ + +++QEL + + + QQQ+ E+
Sbjct: 1341 QDLEKTKLEEQVQELESLISSLQQQLKETEQ 1371
Score = 35.5 bits (78), Expect = 0.64
Identities = 88/449 (19%), Positives = 202/449 (44%), Gaps = 50/449 (11%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E+ E+ T +L EKL T+ + + R++ + +QL++ I+ L VK L+ + Q
Sbjct: 944 EVVEKDTTELM--EKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQ 1001
Query: 321 KEV---QLEARARKLR-ESLKTGEVTTSQLI--------QQRDSLQAEVLECKQQIEKLT 368
+ +LE R E++++ + S L+ + + ++V + + K+
Sbjct: 1002 VSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIM 1061
Query: 369 VQHKSAIQQLE--EDLKQTKRALQEQCEITKR-EIELKERTETE-LQDSRNAIEELQAKI 424
V+ K + + + E+ KQ + L +TK + + +E + LQ N ++ Q +
Sbjct: 1062 VEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDL 1121
Query: 425 -IELEKSKPNPDLPTEREIDLWAELQATK--ETLRVTEDEVTTCKREKESE----NKIGI 477
+++E + L +D E + + L ++E+ + EK E +++ +
Sbjct: 1122 RLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFAQEEKIKELQKIHQLEL 1181
Query: 478 QQKLAAELLNKEE----IIGKMQIQTRELIKNIKLNEQKVI--QYEQYVR-DLQAHNRTI 530
Q E ++ + +IGK+Q E V+ Y ++ ++ A ++
Sbjct: 1182 QTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKEN 1241
Query: 531 ANCQESPN-GISYQDLQQEIMDLKMKLLDVVHR-NEELSEILAKKDQ------------E 576
+ S N QD + E+ D + + ++++ EE +++L + + +
Sbjct: 1242 SGDYISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMK 1301
Query: 577 LEQQDKN-SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAA 635
LE ++N + + + I ++ N L++ + +L++L QDLE + ++ ++V + +
Sbjct: 1302 LEFGEENLPKEETEFLSIHSQMTN-LEDIDVNHKSKLSSL-QDLE-KTKLEEQVQELESL 1358
Query: 636 KADEIQELFATLENKQQQIHRLEKIVLAL 664
+ Q+L T +N + +IH L+K + A+
Sbjct: 1359 ISSLQQQLKETEQNYEAEIHCLQKRLQAV 1387
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 77.4 bits (182), Expect = 2e-13
Identities = 97/478 (20%), Positives = 220/478 (46%), Gaps = 42/478 (8%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA---LVREVAKLRQDVETRNVMIDEIRE 244
ELK + DL + E+ TL V E L++ +L V+ + ++E E
Sbjct: 894 ELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEE 953
Query: 245 LRSE-SENTKALE----EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+ SE + + LE E++ E+D+ ++ L +E + R T ++V + +++
Sbjct: 954 INSELTARGRKLEDECFELKKEIDD-------LETMLVKSEKEKRTTEHKVKNLTEEVEF 1006
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE--- 356
I+ L K++++ +Q L KL K Q+ + +L+ E
Sbjct: 1007 LNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKA 1066
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
+ C++++ KL K + + E+L+ ++R L E E+ K+E+EL + +++++ +
Sbjct: 1067 RMNCERELHKLEGNLKLNRESM-ENLESSQRHLAE--ELRKKELELSQ-MNSKVENEKGL 1122
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG 476
+ +LQ + EL+ DL + E + + +E +T+D +R +E +G
Sbjct: 1123 VAQLQKTVKELQTQ--IKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEE----VG 1176
Query: 477 IQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL-QAHNRTIANCQE 535
E+ K+E K+Q R++ E+ + +E L + H ++A +
Sbjct: 1177 GSSLAQLEITKKQET--KIQKLHRDM-------EEATLHFETTSASLKKRHADSLAELEG 1227
Query: 536 SPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELE-QQDKNSRGQARVIK 592
+ Q L+++ DL++++ D++ R E+++ A ++ +++ A++ K
Sbjct: 1228 QVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDK 1287
Query: 593 IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
+ +L N L ++T+ E + LE + ++++++++ + +I++L LE +
Sbjct: 1288 V-TQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKE 1344
Score = 66.1 bits (154), Expect = 4e-10
Identities = 91/433 (21%), Positives = 187/433 (43%), Gaps = 29/433 (6%)
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR---QKEVQLEAR 328
+++ L +E Q + + + + ++ + + + T+ +E+Q + ++QLEAR
Sbjct: 881 LQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEAR 940
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL-TVQHKSAIQQLEEDLKQTKR 387
++L E ++ E S+L + L+ E E K++I+ L T+ KS ++ + + +
Sbjct: 941 VKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKS--EKEKRTTEHKVK 998
Query: 388 ALQEQCEITKREIELKERTETELQDS-RNAIEELQAKIIELEKSKPNPDLPTEREID-LW 445
L E+ E +I R +Q++ + +++L + +L S +L E+++D L
Sbjct: 999 NLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKL-SSLSKANLKLEQQVDELE 1057
Query: 446 AELQATKETLRVTEDEV----TTCKREKES-ENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
L+ ++ E E+ K +ES EN Q+ LA EL KE + +M
Sbjct: 1058 GALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQM----- 1112
Query: 501 ELIKNIKLNEQK--VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD 558
N K+ +K V Q ++ V++LQ + + E+ + +++E DL L D
Sbjct: 1113 ----NSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAER-TTRAKMERERADLTQDLAD 1167
Query: 559 VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQD 618
+ NE L E+ +LE K ++ + EE + + A +
Sbjct: 1168 L---NERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETTSASLKKRHADSLAE 1224
Query: 619 LEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXX 678
LE ++ + +V +++ ++Q L + +Q+ R + L
Sbjct: 1225 LEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAK 1284
Query: 679 XXKIAALEHELAA 691
K+ L ++LAA
Sbjct: 1285 LDKVTQLANDLAA 1297
Score = 58.8 bits (136), Expect = 6e-08
Identities = 107/532 (20%), Positives = 222/532 (41%), Gaps = 52/532 (9%)
Query: 156 NLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLI 215
+L ++ G L L Q ++ R+++ T L KR L
Sbjct: 1167 DLNERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETTSASLKKRHADSLAELE 1226
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIK-E 274
E L + KL +D + +D++ + KA E L EER + K +
Sbjct: 1227 GQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLD 1286
Query: 275 KLTTTESQLRQTRNRV----AKMDKQLREAEASITSL----TGTVKMLEDQSRQKEVQLE 326
K+T + L + ++ + ++L E EA I L + + +ED Q E + +
Sbjct: 1287 KVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETK 1346
Query: 327 A---------RARK----LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKS 373
+ +A++ LRE + + ++L + + AE+++ + + E +Q
Sbjct: 1347 SQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTE 1406
Query: 374 AIQQLEEDLK-QTKRALQEQCEITKREIEL---KERTETELQDS-------RNAIEELQA 422
++ +++L + + A + R L + + + EL D+ R+A L
Sbjct: 1407 DLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQ 1466
Query: 423 KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLA 482
K +L+ K D + E + A L A+++ ++ E+ K E E+ +G Q+ L
Sbjct: 1467 K--QLQSGKALADWKQKHE-ESQALLDASQKEVQALSTELLKLKNTYE-ESIVG-QETLR 1521
Query: 483 AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISY 542
E N +E I + Q RE KN+ E+ E+ ++Q +E+ +
Sbjct: 1522 RENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQ------VTLEETEGALER 1575
Query: 543 QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLK 602
+ +I+ +++LL+ EL L++KD+E+E + + Q + ++ L + K
Sbjct: 1576 N--ESKILHFQLELLEA---KAELERKLSEKDEEIE--NFRRKQQCTIDSLQSSLDSEAK 1628
Query: 603 NKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
++ E +R +++DL + N+Q++ + +L +++ Q Q+
Sbjct: 1629 SR-IEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQL 1679
Score = 55.6 bits (128), Expect = 6e-07
Identities = 122/569 (21%), Positives = 240/569 (42%), Gaps = 66/569 (11%)
Query: 119 EVAQLYRDAIASSTP---ENA--LELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLS 173
+V QL D A T E+ L L+E + N + K+N T + G + +
Sbjct: 1287 KVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETK 1346
Query: 174 RYNDQGFELCGALRE---LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ 230
+ L A R+ L+ Q E+ +L RTL V +V+ K
Sbjct: 1347 SQSALAHALQKAQRDCDLLREQYEEEQEVKAEL-------HRTLSKVNAEMVQWRMKYEN 1399
Query: 231 DVETRNVMIDEIR-ELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
+V R +++ + EL E +A+ A+ ++ +L S L + R+
Sbjct: 1400 NVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRS 1459
Query: 289 RVAKMD-KQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLI 347
A++D KQL+ +A K E Q+ Q E +A E LK ++
Sbjct: 1460 AAARLDQKQLQSGKALAD---WKQKHEESQALLDASQKEVQALST-ELLKLKNTYEESIV 1515
Query: 348 QQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTE 407
Q ++L+ E +++I LT Q + + L E +++ K+ ++E+ K +
Sbjct: 1516 GQ-ETLRRENKNLQEEISNLTNQVREGTKNLTE-MEKVKKLIEEE----------KTEVQ 1563
Query: 408 TELQDSRNAIEELQAKII--ELEKSKPNPDL-----PTEREIDLW-AELQATKETLRVTE 459
L+++ A+E ++KI+ +LE + +L + EI+ + + Q T ++L+ +
Sbjct: 1564 VTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSL 1623
Query: 460 D-------EVTTCKREKESE-NKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNIKLNE 510
D EVT K++ E + N++ +Q A ++ + +G++QIQ ++L + +
Sbjct: 1624 DSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDST 1683
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
Q ++ V + N + + E + +Q ++ +++ E ++
Sbjct: 1684 QLNSDLKEQVAVAERRNSLLQSELEDLRSLQ----EQTERGRRLSEEELLEATERINLFY 1739
Query: 571 AKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVN 630
+ L Q+ K AR+ K EE++ +N E+ + AA++ ++
Sbjct: 1740 TQNTSLLSQKKKLEADVARMQKEAEEVVQECQN--AEEKAKKAAIE---------AANLS 1788
Query: 631 KQIAAKADEIQELFATLENKQQQIHRLEK 659
+++ K D I L T EN +Q I L+K
Sbjct: 1789 EELKKKQDTIAHLERTRENMEQTITDLQK 1817
Score = 54.0 bits (124), Expect = 2e-06
Identities = 113/560 (20%), Positives = 216/560 (38%), Gaps = 40/560 (7%)
Query: 117 AQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYN 176
A+++ LY + + +T + LD+ + N + KT L G+ L L
Sbjct: 1267 AEKLCTLYEERLHEATAK-----LDKVTQLANDLAAQKTKLW----SESGEFLRRLE--- 1314
Query: 177 DQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV---REVAKLRQDVE 233
E + +L + + + DL + E ++ A+ AL R+ LR+ E
Sbjct: 1315 ----EKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYE 1370
Query: 234 TRNVMIDEIRELRSESENTKALEEMRHELDE-ERTAKLA-IKEKLTTTESQLRQTRNRVA 291
+ E+ S+ M++E + +RT L K++L + +
Sbjct: 1371 EEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVAN 1430
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
+ L A + G + R +L+ + + ++L + + D
Sbjct: 1431 ARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLD 1490
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
+ Q EV ++ KL ++ +I +E L++ + LQE+ ++ + TE++
Sbjct: 1491 ASQKEVQALSTELLKLKNTYEESIVG-QETLRRENKNLQEEISNLTNQVREGTKNLTEME 1549
Query: 412 DSRNAIEELQAKI-IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
+ IEE + ++ + LE+++ + + + EL K L E ++++E
Sbjct: 1550 KVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAEL-----ERKLSEKDEE 1604
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK--LNEQKVIQYEQYVRDLQAHNR 528
EN QQ L + + K +I+ L K ++ LNE + +Q R + +
Sbjct: 1605 IENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEME-LQLSCANRQVSEATK 1663
Query: 529 TIANCQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
++ Q + Q D Q DLK ++ RN L L EQ ++ R
Sbjct: 1664 SLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRL 1723
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEV-----NKQIAAK--ADE 639
+ E IN+ + T + L+ D+ + +EV N + AK A E
Sbjct: 1724 SEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIE 1783
Query: 640 IQELFATLENKQQQIHRLEK 659
L L+ KQ I LE+
Sbjct: 1784 AANLSEELKKKQDTIAHLER 1803
Score = 48.4 bits (110), Expect = 9e-05
Identities = 82/423 (19%), Positives = 176/423 (41%), Gaps = 34/423 (8%)
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
KL Q V+ +++ R+ R E + L ++ L R + ++ +LR+
Sbjct: 1048 KLEQQVDELEGALEQERKARMNCE--RELHKLEGNLKLNRESMENLESSQRHLAEELRKK 1105
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+++M+ ++ + + L TVK L+ Q + + +LEA R R ++ +Q
Sbjct: 1106 ELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAE-RTTRAKMERERADLTQD 1164
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
+ + EV ++T + ++ IQ+L D+++ LK+R
Sbjct: 1165 LADLNERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEA------TLHFETTSASLKKRH 1218
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
L + +E LQ +LEK K DL E + L Q T+ + +++ T
Sbjct: 1219 ADSLAELEGQVENLQQVKQKLEKDK--SDLQLEVDDLLTRVEQMTR--AKANAEKLCTLY 1274
Query: 467 REK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ----YV 520
E+ E+ K+ +LA +L ++ K+ ++ E ++ ++ E + Q + +
Sbjct: 1275 EERLHEATAKLDKVTQLANDLAAQKT---KLWSESGEFLRRLEEKEALINQLSREKSNFT 1331
Query: 521 RDLQAHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELE 578
R ++ + +S + +++ Q Q++ L+ + + EL L+K + E+
Sbjct: 1332 RQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMV 1391
Query: 579 QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
Q + + VI+ E+L + +ELA Q+ M + + N +
Sbjct: 1392 QW--RMKYENNVIQRTEDL--------EDAKKELAIRLQEAAEAMGVANARNASLERARH 1441
Query: 639 EIQ 641
++Q
Sbjct: 1442 QLQ 1444
Score = 48.0 bits (109), Expect = 1e-04
Identities = 56/249 (22%), Positives = 101/249 (40%), Gaps = 12/249 (4%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEI-RE 244
LR L+ Q E + A +L+ + KL DV +E+ +E
Sbjct: 1710 LRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQE 1769
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-S 303
++ E K L EE K L T + QT + + K+L EAE +
Sbjct: 1770 CQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQT---ITDLQKRLAEAEQMA 1826
Query: 304 ITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDSLQAEVLEC 360
+ ++ LE + R+ E +LE R+ E+ + E +L Q + + +
Sbjct: 1827 LMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRM 1886
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
+ Q++KL ++ ++ QQ+E Q + L + + E+KER E + + + +L
Sbjct: 1887 QTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEV----AESQVNKL 1942
Query: 421 QAKIIELEK 429
+ K E K
Sbjct: 1943 KIKAREFGK 1951
>AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein.
Length = 1943
Score = 77.0 bits (181), Expect = 2e-13
Identities = 100/423 (23%), Positives = 189/423 (44%), Gaps = 29/423 (6%)
Query: 243 RELRSESENTKALEEMRHELDEE---RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
R+LR+E + + E ++E R + KE E + Q R R +QL+E
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA----QQLQE 851
Query: 300 AEASITSLTGTVKMLEDQSRQK-EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
E + + E + QK QLE ++ R +L QL +++ LQ E
Sbjct: 852 EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIE 418
E +++ + K Q+ E ++ ++ QE+ ++ + E E + R E E Q ++ +
Sbjct: 912 ELQRE-----EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD--K 964
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+LQ K +L +P ERE + +E L+ E+++ +REK + Q
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQERE-----KKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIK-LNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+ EL +EE + + + + R L + + E++ +Q E+ L R QE
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE--EQLLGEERETRRRQELE 1077
Query: 538 NGI-SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREE 596
++LQQE L + + R E E ++++EL+Q+++ + R + R+E
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQER--ERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 597 LINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
L + +E Q E L+++ E R R E+ +Q + +E+Q+ L ++Q+ R
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRR--QELERQY-REEEELQQEEEQLLREEQEKRR 1192
Query: 657 LEK 659
E+
Sbjct: 1193 QER 1195
Score = 70.1 bits (164), Expect = 2e-11
Identities = 98/465 (21%), Positives = 210/465 (45%), Gaps = 27/465 (5%)
Query: 210 ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAK 269
ER+ L + ++ +LR++ + R +E RE + E ++ R E EER +
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE----QQERREQQEERREQ 337
Query: 270 LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARA 329
+E+ E QLR+ + + ++QLR E ++ + R+++++ E +
Sbjct: 338 QLRREQEERREQQLRREQEE-ERREQQLRR-EQEEERREQQLRREQQLRREQQLRREQQL 395
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL 389
R+ ++ + ++ Q +++ L+ E ++Q E+ +H+ +Q E ++ KR
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE---RHEQKHEQ-ERREQRLKREQ 451
Query: 390 QEQCEITKREIELK--ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAE 447
+E+ + KRE E + E+ + Q R+ EE + + ++LE+ + + RE L E
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE-RREQQERREQQLRRE 510
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRE--LIKN 505
+ +E ++E ++ SE ++ +Q+ E L K E +++ + RE L +
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
+ ++++ E+ R + ++ + L+QE + +L E
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE-ERREQRLKREEPEEER 629
Query: 566 LSEILAKKDQELEQQ-----DKNSRGQARVIKIREE--LINVLKNKETEQSRELAALQQD 618
++L ++QE +Q ++ R + R+ + EE L LK + E+ RE +++
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 619 LEH-RMRIVDEVNK---QIAAKADEIQELFATLENKQQQIHRLEK 659
E R RI + K Q+ ++AD Q + KQ+ R ++
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE 734
Score = 62.9 bits (146), Expect = 4e-09
Identities = 94/444 (21%), Positives = 201/444 (45%), Gaps = 38/444 (8%)
Query: 233 ETRNVMIDEIRELRSESENTKALEEMRHELDEER-TAKLAIKEKLTTTESQLRQTRNRVA 291
E ++E ++L + K L+E + +ER + +++ E QLRQ R
Sbjct: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Query: 292 ----KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLI 347
+ D++ R E + K +ED+ + + + + + R+ R+ K E QL+
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR-KFRE--DEQLL 1628
Query: 348 QQRDSLQAEVLECKQQI--EKLTVQHKSAIQQLEED----LKQTKRALQE--QCEITKRE 399
Q+R+ Q E ++ E+ ++ + QQL D ++ ++ LQE + ++ ++E
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE 1688
Query: 400 IELKERTETEL-----QDSRNAIEELQAKIIELE-KSKPNPDLPTEREIDLWAELQATKE 453
+ K R E + ++ + EE Q + ELE K + L E E + +L+ +
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE---QLRRQER 1745
Query: 454 TLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV 513
++ E+E +RE++ + +K E ++E + + Q R + K E++
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE---REEQQLRSQESDRKFREEEQ 1802
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE---LSEIL 570
++ E+ + L+ R + + ++ +Q + + D +R EE E
Sbjct: 1803 LRQEREEQQLRPQQRD-GKYRWEEEQLQLEEQEQRLRQER----DRQYRAEEQFATQEKS 1857
Query: 571 AKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ-QDLEHRMRIVDEV 629
+++QEL Q+++ R Q R K+REE I + KE ++ R++ ++ Q+ + R+++
Sbjct: 1858 RREEQELWQEEEQKRRQERERKLREEHIR-RQQKEEQRHRQVGEIKSQEGKGHGRLLEPG 1916
Query: 630 NKQIAAKADEIQELFATLENKQQQ 653
Q A+ L+ ++ ++ Q
Sbjct: 1917 THQFASVPVRSSPLYEYIQEQRSQ 1940
Score = 61.7 bits (143), Expect = 9e-09
Identities = 109/492 (22%), Positives = 212/492 (43%), Gaps = 31/492 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
RE + + E+ + KR E R + E E + R+ +++R E
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAE---EEQEQARERIKSRIPKWQWQLESE 711
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTR--NRVAKMDKQLREA---- 300
+++ +K R + + R + K + +E Q ++ +R + ++Q R+
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQW 771
Query: 301 EASITSLTGTVKMLEDQS--RQKEVQLEARARKLRES--LKTGEVTTSQLIQQRD-SLQA 355
+A S G ++ Q+E QL A R+ RE L E + Q+R+ +
Sbjct: 772 QAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL 831
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLK--QTKRALQEQCEITKREIELKERTETELQD- 412
+ LE ++Q+++ + +Q+ E+ L+ Q +R QEQ K +L+E +
Sbjct: 832 QFLEEEEQLQRR--ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL 889
Query: 413 -SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT---KETLRVTEDEVTTCKRE 468
++ A++E K +L + + ERE E + +E L+ E+++ +RE
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 469 KESENKIGIQQKLAAELLNKEE-IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
K + Q + +L KEE ++G+ + R + K E++ +Q E+ L
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE--EQLLREE 1007
Query: 528 RTIANCQESPNGISYQD-LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
R QE +D LQQE L + + R + E ++++EL+Q+++ G
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREERE--KRRLQERERQYREEEELQQEEEQLLG 1065
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ R + R+EL + +E Q E L+++ E R R E +Q + + QE
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR--QERERQCREEEELQQEEEQL 1123
Query: 647 LENKQQQIHRLE 658
L ++++ R E
Sbjct: 1124 LREEREKRRRQE 1135
Score = 60.9 bits (141), Expect = 1e-08
Identities = 104/460 (22%), Positives = 204/460 (44%), Gaps = 43/460 (9%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
E+ + RQ+ + R E +L+S + EE E R L ++ K + Q
Sbjct: 172 ELWRQRQEWQEREERRAEEEQLQSCKGHET--EEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQS--RQKEVQLEARARKLRESLKTGEV 341
R+ R +++ +E T L + L+++ RQ+E+Q E E L+ E
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE------EEQLRKLER 283
Query: 342 TTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE 401
+ +Q + Q + L +QQ+ + + + QQ E +Q +R QE+ + E
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERRE-QQEERREQQERREQQEERREQQLRRE 342
Query: 402 LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDE 461
+ER E +L+ R EE + + + E+ + + RE L E Q +E E +
Sbjct: 343 QEERREQQLR--REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 400
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN-IKLNEQKVIQYEQYV 520
+ +RE++ + QQ + L +E+ + + Q + R K+ + EQ++ + ++
Sbjct: 401 L---RREQQLRRE---QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454
Query: 521 RD-LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE-------LSEILAK 572
RD L+ T + QE +D ++E + +KL + R ++ E +
Sbjct: 455 RDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER 514
Query: 573 KDQELEQQDKNSRGQARV----------IKIREELINVLKNKETEQSRELAALQQDLEHR 622
++Q L++Q++ R Q R+ + RE+L+ + K EQ R L+++ E R
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEER 574
Query: 623 MRIV---DEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ +E +Q K ++ + L L K++++ RLE+
Sbjct: 575 RDQLLKREEERRQQRLKREQEERLEQRL--KREEVERLEQ 612
Score = 60.5 bits (140), Expect = 2e-08
Identities = 97/447 (21%), Positives = 188/447 (42%), Gaps = 24/447 (5%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHEL--DEERTAKLAIKEK- 275
+ L RE R+ R + ++LR E + + EE RHE ++ER + +E+
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 276 -----LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
L E R + R + K+ +E E L + +Q ++E QL
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512
Query: 331 KLRES-LK--TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
+ RE LK E Q ++ L+ E E ++Q+ K + + ++ E+ LK+ +
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Query: 388 ALQEQC---EITKREIELKERTETELQD--SRNAIEELQAKIIELEKSKPNPDLPTEREI 442
++Q E +R+ LK E L+ R +E L+ + ++ K R+
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ 632
Query: 443 DLWAELQATK--ETLRVTEDE--VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQ 498
L +E Q + + LR + E KRE+E E ++ E ++E+ + Q Q
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Query: 499 TRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD 558
RE IK+ Q ++ E R + ++R + + ++ +L+ + +
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE 752
Query: 559 VVHRNEELSEILAKKDQELEQQDKNSRGQARVI---KIREELINVLKNKETEQ-SRELAA 614
HR ++ E + + ++K+ RG+ R+ +RE+ L+ +E +Q +
Sbjct: 753 RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLP 812
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQ 641
+++ E R R E K++ +E Q
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQ 839
Score = 60.1 bits (139), Expect = 3e-08
Identities = 96/483 (19%), Positives = 208/483 (43%), Gaps = 33/483 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
R+ K+Q E + KR E E L++E + + R+ E ELR
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE-EELR 1368
Query: 247 SESENTKALEEMRHELDEERTAKLAIKE---KLTTTESQLRQTRNRVAKMDKQLREAEAS 303
+ + K LEE + +ER K +E + E QLRQ R+R + ++Q +
Sbjct: 1369 HQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428
Query: 304 ITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
+ + Q R+++ E + + K E QL+Q+R+ Q +Q+
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE--EEQLLQEREEQQLH----RQE 1482
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ ++ + +++ E D K ++ L+ Q E ++ +E +++ + Q R ++E Q
Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQ-EPERKFLEEEQQLHRQ-QRQRKFLQEEQ-- 1538
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE---SENKIGIQQK 480
+L + + +R+ E Q +E E +++ +R+++ E K+ Q++
Sbjct: 1539 --QLRRQERGQQRRQDRDRKFREEEQLRQER---EEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGI 540
+ +++++ + Q ++ K E + + E+ + L R +E P +
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQ-L 1652
Query: 541 SYQDLQQEIM-DLKMKLLD---VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREE 596
Q+ +Q++ D K + ++ EE ++D++ ++++ R Q R K +E
Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQE 1712
Query: 597 LINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ + + + RE L+Q+ E E ++I ++E E ++QQ+ R
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI------LEEEQLRPEREEQQLRR 1766
Query: 657 LEK 659
E+
Sbjct: 1767 QER 1769
Score = 59.3 bits (137), Expect = 5e-08
Identities = 90/437 (20%), Positives = 195/437 (44%), Gaps = 21/437 (4%)
Query: 233 ETRNVMIDEIRELRSESENT-KALEEMRHELDEERTAKLAIKEKLTTTESQL-RQTRNRV 290
E ++E ++LR E + E++ E +E++ + K E QL RQ R+R
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSR----QKEVQL--EARARKLRESLKTGEVTTS 344
+ +++LR E L ++ Q + Q+E QL + R ++ R+
Sbjct: 1503 FR-EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
Query: 345 QLIQQRD--SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL 402
QL Q+R+ L + + K ++E+ V+ + ++ ED +Q +R QE + ++E +
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR--QEGQQQLRQERDR 1619
Query: 403 KERTETELQDSRNAIEELQAKIIELEKSKPNPDL-PTEREIDLW--AELQATKETLRVTE 459
K R + +L R ++L + + + + P L ERE L + + +E + E
Sbjct: 1620 KFREDEQLLQEREE-QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
E +R++ +Q+L + ++ + + Q++ +EL + + EQ + EQ
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
Q R I ++ Q L+++ D K + + + + E ++ +++ +
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798
Query: 580 QDKNSRGQARVIKIREELINVLKNKETEQ---SRELAALQQDLEHRMRIVDEVNKQIAAK 636
+++ R + ++R + + E EQ + L+Q+ + + R ++ Q ++
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
Query: 637 ADEIQELFATLENKQQQ 653
+E QEL+ E K++Q
Sbjct: 1859 REE-QELWQEEEQKRRQ 1874
Score = 58.0 bits (134), Expect = 1e-07
Identities = 98/488 (20%), Positives = 210/488 (43%), Gaps = 25/488 (5%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS 247
E + Q E+ +R E L E L+RE + R+ E R + ++L+
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE-RERQYRKDKKLQQ 968
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL---RQTRNRVAKMDKQLREAEASI 304
+ E EE +ER K +E+L E QL + + R + ++Q R+ +
Sbjct: 969 KEEQLLG-EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD--- 1024
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
L + L + R+K +L+ R R+ RE + + L ++R++ + + LE + +
Sbjct: 1025 -ELQQEEEQLLREEREKR-RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIEL-----KERTETELQDSRN 415
E+ Q + + + EE K+ ++ + QC E+ + E +L ++R EL+
Sbjct: 1083 EEELQQEEEQLLR-EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 416 AIEELQAKIIELEKSKPNP--DLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESEN 473
EE+Q + +L + +P ER+ ELQ +E L E E +RE++
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
+ +Q++ + E+ ++ Q +N + + + + + Q + + +
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD- 1260
Query: 534 QESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-SEILAKKDQELEQQDKNSRGQARVIK 592
++S + + +Q+ D + + R+ E +++++ E + ++ + Q
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320
Query: 593 IREELINVLKNKETEQS-RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+REE + +ET++ RE L Q+ E + E +++ + QE ++
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 652 QQIHRLEK 659
Q++ R E+
Sbjct: 1381 QRLRRQER 1388
Score = 44.8 bits (101), Expect = 0.001
Identities = 70/359 (19%), Positives = 166/359 (46%), Gaps = 22/359 (6%)
Query: 309 GTVKMLEDQSRQKEVQ--LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
G +L+D+ RQ+E Q E R R+L E + G+ + Q+R + E+ E ++Q EK
Sbjct: 105 GKESLLQDR-RQEEDQRRFEPRDRQLEE--EPGQ----RRRQKRQEQERELAEGEEQSEK 157
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE 426
+ Q+ +E+L + ++ QE+ E E +L+ E ++ + + + +++E
Sbjct: 158 QERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLE 217
Query: 427 LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELL 486
L + RE + ++ R E T ++E+E + Q++ EL
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE---TVLRKEEEKLQEEEPQRQ--RELQ 272
Query: 487 NKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
+EE + K++ Q + + +Q+ ++ EQ +R Q R +E ++ Q
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERR-EQQEERREQQERREQQ 331
Query: 547 QEIMDLKMKLLDVVHRNEEL--SEILAKKDQELEQQDKNSRGQ---ARVIKIREELINVL 601
+E + +++ R ++L + +++Q+L ++ + R + R ++R E +
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ-QLR 390
Query: 602 KNKETEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ ++ + ++L QQ E ++R ++ ++ + ++ +E ++++ RL++
Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Score = 35.5 bits (78), Expect = 0.64
Identities = 40/180 (22%), Positives = 80/180 (44%), Gaps = 6/180 (3%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL-- 276
E RE +LRQ+ E + E E E + E + +ER K +E+L
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ 1781
Query: 277 TTTESQLR-QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
E QLR Q +R + ++QLR+ E L + + + ++++QLE + ++LR+
Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQ-EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE 1840
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
Q Q S + E +++ +K + + ++ EE +++ ++ Q ++
Sbjct: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR--EEHIRRQQKEEQRHRQV 1898
>AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and
Golgi-localized PKN-associated protein (CG-NAP) protein.
Length = 3899
Score = 77.0 bits (181), Expect = 2e-13
Identities = 98/446 (21%), Positives = 203/446 (45%), Gaps = 38/446 (8%)
Query: 232 VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
V +M + R+ + +E+ K EE+R L EE A+ + +L+ E + +
Sbjct: 1873 VTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKT 1932
Query: 292 KMDKQLREA-------EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT--GEVT 342
++Q++E E + + ++ LE + +Q + + E +R+ +E++K G V
Sbjct: 1933 LFERQIQEKTDVIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ-KEAMKAEAGPVE 1991
Query: 343 TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL 402
QL+Q+ + L E LE + Q EK+ + ++ LE D++ E R IEL
Sbjct: 1992 -QQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVE----------EQVSRFIEL 2040
Query: 403 KERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLRVTEDE 461
++ TEL D R + L+ ++ ++ K + E E D++ E+Q ++ L+V
Sbjct: 2041 EQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVP-- 2098
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVR 521
+ + SE++ ++LA L K + ++ + +L ++I+ +++ + E VR
Sbjct: 2099 ----RFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVR 2154
Query: 522 DL-QA---HNRTIANCQESPNGISYQ---DLQQEIMDLKMK-LLDVVHRNEELSEILAKK 573
+L QA +R E+ +S + +++ +D K K + ++ + E+ E L K
Sbjct: 2155 ELVQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENK 2214
Query: 574 DQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI 633
++E++Q Q + R + + +NK + E L M D+ +
Sbjct: 2215 NEEVQQLHMQLEIQKKESTTRLQELE-QENKLFKDDMEKLGLAIKESDAMSTQDQ-HVLF 2272
Query: 634 AAKADEIQELFATLENKQQQIHRLEK 659
A IQE ++ +Q+ +L++
Sbjct: 2273 GKFAQIIQEKEVEIDQLNEQVTKLQQ 2298
Score = 68.9 bits (161), Expect = 6e-11
Identities = 102/487 (20%), Positives = 217/487 (44%), Gaps = 61/487 (12%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALV---REVAKLRQDVETRNVMIDEIRELR 246
K + ++ + +L+ + E + + + + L + + +L++ + +N EI+ ++
Sbjct: 321 KEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN---QEIKNMK 377
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ--TRNRVAKMDKQLREAEASI 304
E N+K E E ++ + +K +SQ + + ++L + A +
Sbjct: 378 LELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAEL 437
Query: 305 TSLTGT--VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
+ G V+M ++ RQ Q+E + + ++ + S + D ++
Sbjct: 438 DEMYGQQIVQMKQELIRQHMAQMEEIKTRHKGEMENALRSYSNITVNEDQIKL----MNV 493
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER---TETELQDSRNAIEE 419
I +L ++ + Q E+ ++ L+E+C + ++ +L E + ++Q +R I E
Sbjct: 494 AINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRGQIQRARQTIAE 553
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
++K+ E KS + DL AE+ + E+ + E K E E N
Sbjct: 554 QESKLNEAHKSLSTVE-------DLKAEIVSASESRKELE-----LKHEAEVTN-----Y 596
Query: 480 KLAAELLNKEE--IIGKM-QIQTRELIKNIKLNEQKVIQYEQYV----RDLQAHNRTIAN 532
K+ E+L KE+ ++ +M + Q EL + L+ Q + +E+ + DL+ +R
Sbjct: 597 KIKLEMLEKEKNAVLDRMAESQEAELER---LSTQLLFSHEEELSKLKEDLEIEHRISIE 653
Query: 533 CQESPNGISYQ---DLQQEIMDLKMKLLD------VVHRNEELSEILAKKDQELEQQDKN 583
+ GI Y+ D Q M K++ + + +N+ + EI KD L+Q N
Sbjct: 654 KLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKD--LQQSLVN 711
Query: 584 SRGQARVIKIRE--ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
S+ + ++I E + I +L+ +E E+ L+Q+++ + + KQ+ K +++Q
Sbjct: 712 SKSEEMTLQINELQKEIEILRQEEKEKG----TLEQEVQELQLKTELLEKQMKEKENDLQ 767
Query: 642 ELFATLE 648
E FA LE
Sbjct: 768 EKFAQLE 774
Score = 67.3 bits (157), Expect = 2e-10
Identities = 120/538 (22%), Positives = 231/538 (42%), Gaps = 52/538 (9%)
Query: 134 ENALELLDETMPIENIIKYPKTNL---TVNQDQTDGDILEHLSRYNDQGFELCGALRELK 190
E LE + ET K +T L + Q Q + L+ ++ E A +L
Sbjct: 1855 EKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLA 1914
Query: 191 TQ---AEDAVNTVTD---LSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
+ AE ++ D L +R E+ +I E + + Q++E I E RE
Sbjct: 1915 VELSKAEGVIDGYADEKTLFERQIQEKTDVIDRLEQELLCASNRLQELEAEQQQIQEERE 1974
Query: 245 LRSESENTKALE--EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
L S + E + +L +E T KL +KEKL + Q + R+ + KQ++ E
Sbjct: 1975 LLSRQKEAMKAEAGPVEQQLLQE-TEKL-MKEKL-EVQCQAEKVRD---DLQKQVKALEI 2028
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESL-KTGEVTTSQLI---QQRDSLQAEVL 358
+ LE + + + L + + L + L K + Q I +RD Q E+
Sbjct: 2029 DVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ 2088
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIE 418
+ +QQ+ K+ + + + +++Q L+E+ + + KE+ + ++Q+ IE
Sbjct: 2089 KLEQQL-KVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIE 2147
Query: 419 ELQAKIIEL------EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+L+ ++ EL E K + + E+ L +LQA ++ + E E+T + + E
Sbjct: 2148 KLEFRVRELVQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLE-- 2205
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
+ EL NK E + ++ +Q E+ K K + ++ + EQ + + +
Sbjct: 2206 -------QFREELENKNEEVQQLHMQL-EIQK--KESTTRLQELEQENKLFKDDMEKLGL 2255
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK 592
+ + +S QD Q + L K ++ E + L ++ +L+QQ K + +VI+
Sbjct: 2256 AIKESDAMSTQD--QHV--LFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDN-KVIE 2310
Query: 593 IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
+ ELI L+ ++ L D E R +E +Q+ +++Q+ A + K
Sbjct: 2311 EKNELIRDLET-------QIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQK 2361
Score = 61.7 bits (143), Expect = 9e-09
Identities = 91/418 (21%), Positives = 187/418 (44%), Gaps = 31/418 (7%)
Query: 255 LEEMRHELDEER-TAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
+EE+ EL+E R T ++L E+ ++Q + ++ L++A
Sbjct: 171 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLE 230
Query: 314 LEDQSRQKEVQLEA--RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
L +QS++ ++Q + + LR S T T + L+Q + ++L +QQ+E+
Sbjct: 231 LTEQSQKLQIQFQQLQASETLRNS--THSSTAADLLQAKQ----QILTHQQQLEEQDHLL 284
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELK--ERTETELQDSRNAIEELQAKIIELEK 429
+ Q+ +ED LQE+ ++ + E + K + E+Q+ IEEL KIIE EK
Sbjct: 285 ED-YQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEK 343
Query: 430 S--KPNPDLPTEREI--DLWAELQATKETLRVTEDEVTTCK-REKESENKIGIQQKLAAE 484
+ L T ++ +L ++ + ++ + E+T K +E++S +I E
Sbjct: 344 KTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEE 403
Query: 485 LLNKEEIIGKMQ---IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
L + + + +Q E KL + + E Y + + + + Q
Sbjct: 404 LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIR-QHMAQMEE 462
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEIL--AKKDQELEQQDKNSRGQARVIKIREELIN 599
+ + M+ ++ + NE+ +++ A + ++ QD NS+ + K++EEL
Sbjct: 463 IKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE----KLKEELGL 518
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA---AKADEIQELFATLENKQQQI 654
+L+ K Q R+L L ++L + + IA +K +E + +T+E+ + +I
Sbjct: 519 ILEEKCALQ-RQLEDLVEELSFSRGQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEI 575
Score = 57.6 bits (133), Expect = 1e-07
Identities = 82/413 (19%), Positives = 186/413 (45%), Gaps = 30/413 (7%)
Query: 174 RYNDQGFELCGALREL-KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
R +QG E A+ L K ++ + L + + TL E+ L ++
Sbjct: 3059 RIQEQGVEYQAAMECLHKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNI 3118
Query: 233 ETRNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
+ + + E++ EL S + L+E +L E+ +K +L T+ +L T
Sbjct: 3119 QQKQSQMLEMQVELSSMKDRATELQE---QLSSEKMVVAELKSELAQTKLELETTLKAQH 3175
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
K K+L + T V +L D + ++R+L+ +L+ + + ++RD
Sbjct: 3176 KHLKELEAFRLEVKDKTDEVHLLNDTLASEH----KKSRELQWALEKEKAKLGRS-EERD 3230
Query: 352 SLQAEVLECKQQIEKL-TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL 410
+ E L+ + +K +Q ++Q ++ L ++++ ++ Q + ++ ++ EL
Sbjct: 3231 KEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLEL 3290
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
Q ++ + +I E+ + +RE +L A+LQ++ T + + + + KE
Sbjct: 3291 QV---LLQSQKVRIREMSST-------LDRERELHAQLQSSDGTGQ-SRPPLPSEDLLKE 3339
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ ++ + ELLN+ E +QTR+ ++ + +K +Q EQ +A+
Sbjct: 3340 LQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQ-----EANTEGQ 3394
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK-KDQELEQQDK 582
E + + +DLQ+++ + + ++ + + L I+ + + QELE+++K
Sbjct: 3395 KKMHELQSKV--EDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEK 3445
Score = 51.6 bits (118), Expect = 9e-06
Identities = 85/425 (20%), Positives = 185/425 (43%), Gaps = 33/425 (7%)
Query: 72 DRQAVLEVFQNLKSLYERLNNEGISACGE--GFLP-QELILFNVADWTAQEVAQLYRDAI 128
DR+++L Q +L+ ++N I+ E P QEL+ +N+ +Q L
Sbjct: 3078 DRRSLLSEIQ---ALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQ---MLEMQVE 3131
Query: 129 ASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRE 188
SS + A EL ++ + ++ K+ L QT ++ L + EL
Sbjct: 3132 LSSMKDRATELQEQLSSEKMVVAELKSELA----QTKLELETTLKAQHKHLKEL----EA 3183
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR-ELRS 247
+ + +D + V L+ E + + AL +E AKL + E +++++ L S
Sbjct: 3184 FRLEVKDKTDEVHLLNDTLASEHKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLES 3243
Query: 248 ESENTKALE---EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+ + L E + +L E K+ + L ++QL + + R ++ L+ + I
Sbjct: 3244 QKQRNLQLNLLLEQQKQLLNESQQKIESQRMLY--DAQLSEEQGRNLELQVLLQSQKVRI 3301
Query: 305 TSLTGTVKMLEDQSRQKEVQLEAR--ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
++ T+ D+ R+ QL++ + R L + ++ +L +Q + + ++E
Sbjct: 3302 REMSSTL----DRERELHAQLQSSDGTGQSRPPLPSEDLL-KELQKQLEEKHSRIVELLN 3356
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
+ EK + QQ+E+D + ++ LQ + E + +++++D + +EE +
Sbjct: 3357 ETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQ 3416
Query: 423 KI--IELEKSKPNPDLPTEREIDL-WAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
++ ++LE + + ++ +L E + ++ L +E TT + +QQ
Sbjct: 3417 QVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQ 3476
Query: 480 KLAAE 484
K+ E
Sbjct: 3477 KIEGE 3481
Score = 51.2 bits (117), Expect = 1e-05
Identities = 79/383 (20%), Positives = 166/383 (43%), Gaps = 24/383 (6%)
Query: 108 ILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKT--NLTVN-QDQT 164
+L +A+ E+ +L + S E L L E + IE+ I K NL ++ + Q
Sbjct: 610 VLDRMAESQEAELERLSTQLLFSH--EEELSKLKEDLEIEHRISIEKLKDNLGIHYKQQI 667
Query: 165 DGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVG-EALVR 223
DG E + FE + + + Q ++ + DL + + + + + L +
Sbjct: 668 DGLQNEMSQKIETMQFEKDNLITK-QNQLILEISKLKDLQQSLVNSKSEEMTLQINELQK 726
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENT-KALEEMRHELDEE----RTAKLAIKEKLTT 278
E+ LRQ+ + + + E++EL+ ++E K ++E ++L E+ +K++ T
Sbjct: 727 EIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKT 786
Query: 279 TESQLR-----QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQS-RQKEVQLEARARKL 332
E L+ R+ +D +++ S+ + + E++ +Q+ +QL K
Sbjct: 787 LEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQ 846
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE----KLTVQHKSAIQQLEEDLKQTKRA 388
R + E Q+ A +L+ K +E K +++KS ++ L E+L +R
Sbjct: 847 RNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL-NLQRI 905
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE-LEKSKPNPDLPTEREIDLWAE 447
++ + + E + +E+ +++E LE +K ++R DL +
Sbjct: 906 NPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMENLEVTKREKLELSQRLSDLSEQ 965
Query: 448 LQATKETLRVTEDEVTTCKREKE 470
L+ + +EV + K+EKE
Sbjct: 966 LKQKHGEISFLNEEVKSLKQEKE 988
Score = 50.8 bits (116), Expect = 2e-05
Identities = 100/442 (22%), Positives = 202/442 (45%), Gaps = 40/442 (9%)
Query: 181 ELCGALRELKTQAEDAV-NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMI 239
+L G L+E Q + N +L+ ER++ + + L+ V +L++ +
Sbjct: 357 KLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQ-LMGTVEELQKRNHKDSQFE 415
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTE-SQLRQTRNR-VAKMDKQ 296
+I + R E E + LE++R ELDE ++ +K++L +Q+ + + R +M+
Sbjct: 416 TDIVQ-RMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEIKTRHKGEMENA 474
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLE---ARARKLRESLKTGEVTTSQLIQQRDSL 353
LR + ++IT +K++ + ++L+ ++ KL+E L L +Q + L
Sbjct: 475 LR-SYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDL 533
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
E+ + QI++ + I + E L + ++L E K EI + EL+
Sbjct: 534 VEELSFSRGQIQRA----RQTIAEQESKLNEAHKSLST-VEDLKAEIVSASESRKELELK 588
Query: 414 RNA-IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT-EDEVTTCKREKES 471
A + + K+ LEK K N L E AEL+ L + E+E++ K + E
Sbjct: 589 HEAEVTNYKIKLEMLEKEK-NAVLDRMAESQE-AELERLSTQLLFSHEEELSKLKEDLEI 646
Query: 472 ENKIGIQQ-KLAAELLNKEEIIG-----KMQIQTRELIKNIKLNEQKVIQYE-QYVRDLQ 524
E++I I++ K + K++I G +I+T + K+ + +Q + E ++DLQ
Sbjct: 647 EHRISIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ 706
Query: 525 -------AHNRTIA-NCQESPNGISYQD------LQQEIMDLKMKLLDVVHRNEELSEIL 570
+ T+ N + I Q+ L+QE+ +L++K + + +E L
Sbjct: 707 QSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDL 766
Query: 571 AKKDQELEQQDKNSRGQARVIK 592
+K +LE ++ + + + ++
Sbjct: 767 QEKFAQLEAENSILKDEKKTLE 788
Score = 45.6 bits (103), Expect = 6e-04
Identities = 85/465 (18%), Positives = 203/465 (43%), Gaps = 39/465 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
+R+L+TQ E +S + C +R + E L + KL+Q++ I + +
Sbjct: 2316 IRDLETQIECL------MSDQECVKRNREEEI-EQLNEVIEKLQQELAN----IGQKTSM 2364
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ S + +A + ++H+LD KLA+++++ T ++ +N + + + ++ + +
Sbjct: 2365 NAHSLSEEA-DSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELF 2423
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
SL + +E E + L + EV ++ D+L++ LE + +
Sbjct: 2424 SLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTE-----DALKS--LENQTYFK 2476
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTETELQDSRNAIEELQAKI 424
K +I LE L+Q + + + E+T+ ++K+ E + E LQ KI
Sbjct: 2477 SFEENGKGSIINLETRLRQLESTVSAKDLELTQCYKQIKDMQE----QGQFETEMLQKKI 2532
Query: 425 IELEK---SKPNPDLPTEREIDL---WAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+ L+K K L ++ +++ +A+ +T+ + + E+++G
Sbjct: 2533 VNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSD 2592
Query: 479 -QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
L + E + +M + +++ E+ V++ E+ + +LQ + + ++
Sbjct: 2593 ISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQ---KLLEGNEKKQ 2649
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEE---LSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ Q++ LK ++ H NEE +E+ A + + + + + + + + K++
Sbjct: 2650 REKEKKRSPQDVEVLK-TTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQ 2708
Query: 595 EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
EEL+ V + T ++L+ ++ L + + K+ + E
Sbjct: 2709 EELL-VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 2752
Score = 39.5 bits (88), Expect = 0.039
Identities = 63/297 (21%), Positives = 136/297 (45%), Gaps = 32/297 (10%)
Query: 357 VLEC-KQQIEKLTVQHKSAIQQLEE-DLKQTKRALQE-QCEITKREIELKERTETELQDS 413
+L C +Q+I++ V++++A++ L + D + +Q ++ R+I LK E+E + S
Sbjct: 3052 LLNCLEQRIQEQGVEYQAAMECLHKADRRSLLSEIQALHAQMNGRKITLKREQESE-KPS 3110
Query: 414 RNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+ +E +Q K ++ + + +R +L +L + K + + E+ K E E+
Sbjct: 3111 QELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETT 3170
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
K Q K EL +++ ++ + L + + R+LQ
Sbjct: 3171 LKA--QHKHLKEL-------EAFRLEVKDKTDEVHLLNDTLASEHKKSRELQ----WALE 3217
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK 592
+++ G S + ++E+ DLK L RN +L+ +L ++ Q L + + I+
Sbjct: 3218 KEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQK-------IE 3270
Query: 593 IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ L + ++E ++ EL L Q + R+R ++++ D +EL A L++
Sbjct: 3271 SQRMLYDAQLSEEQGRNLELQVLLQSQKVRIR-------EMSSTLDRERELHAQLQS 3320
Score = 38.7 bits (86), Expect = 0.069
Identities = 77/419 (18%), Positives = 176/419 (42%), Gaps = 36/419 (8%)
Query: 263 DEERTAKL-AIKEKLTTTESQLRQTRNRV-AKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
DEER KL A K KL + Q+ + +K K+ R+ +S ++ + DQS+
Sbjct: 3 DEERQKKLEAGKAKLAQFRQRKAQSDGQSPSKKQKKKRKTSSSKHDVSAHHDLNIDQSQC 62
Query: 321 KEVQLEARAR---------KLRESLKTGEVTTSQL---IQQRDSLQAEVLECKQQIE--K 366
++ + + R + +L +GE+T+ + ++ + +C ++
Sbjct: 63 NQMYINSSQRVESTVIPESTIMRTLHSGEITSHEQGFSVELESEISTTADDCSSEVNGCS 122
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQ-CEITKREIELKERTETELQDSRNAIEELQAKII 425
++ L E+ + EQ + + +E+ E +EL ++ IEEL ++
Sbjct: 123 FVMRTGKPTNLLREEEFGVDDSYSEQGAQDSPTHLEMME---SELAGKQHEIEELNRELE 179
Query: 426 ELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAEL 485
E+ + L +E + A ++ + + +REK+ + ++ ++
Sbjct: 180 EMRVTYGTEGLQQLQEFE--AAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQK 237
Query: 486 LNKEEIIGKMQIQTRELIKNIKLNEQK--VIQYEQYV----RDLQAHNRTIANCQESPNG 539
L I Q+Q E ++N + ++Q +Q + + L+ + + + Q+
Sbjct: 238 LQ----IQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKED 293
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ Q LQ++I +M+ D N EI K+ E K + + ++++++L
Sbjct: 294 FTMQISFLQEKIKVYEMEQ-DKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKL 352
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
K Q + + Q+ ++ + + K+ ++EI++L T+E Q++ H+
Sbjct: 353 TTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE-RQSSEEIKQLMGTVEELQKRNHK 410
>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 76.6 bits (180), Expect = 3e-13
Identities = 105/502 (20%), Positives = 227/502 (45%), Gaps = 51/502 (10%)
Query: 204 SKRACH---ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMR 259
+ +AC+ E + L+ L EVA+L++ ++ + + ++ E E +A LEE+R
Sbjct: 599 NNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLE---VKNQQNIKEERERMRANLEELR 655
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRV--AKMDKQLREAEASITSLTGTVKMLEDQ 317
+ +E+ ++++L +E +LR+ + KM+++ + E ++ L+DQ
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTE---------IRDLQDQ 706
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+ +L++ R E + G + +L+Q + LQ ++L K++ E L +++
Sbjct: 707 LSEMHDELDSAKRS--EDREKGAL-IEELLQAKQDLQ-DLLIAKEEQEDL-------LRK 755
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
E +L K AL+E+ +E++ LKE+ + ELQ R ++EE K +E+ S+ N
Sbjct: 756 RERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSE 814
Query: 437 PTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
+ ++ + LQ E L+ +E+ +R + + +I + L + +E + K
Sbjct: 815 QDQAGTEMRVKLLQEENEKLQGRSEELE--RRVAQLQRQI---EDLKGDEAKAKETLKKY 869
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ + R+L E+ ++ + ++ + R + N E+ G + QE L K
Sbjct: 870 EGEIRQL-------EEALVHARKEEKEAVSARRALENELEAAQG-NLSQTTQEQKQLSEK 921
Query: 556 LLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAAL 615
L + + E+L + K + E E+ + K+++E+ ++++ T L
Sbjct: 922 LKEESEQKEQLRRL--KNEMENERWHLGK----TIEKLQKEMADIVEASRTSTLELQNQL 975
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXX 675
+ E R + E+ +Q+ K E ++ T Q ++ +E+ +
Sbjct: 976 DEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKR 1035
Query: 676 XXXXXKIAALEHELAAGLNRKE 697
+ LE+EL A + K+
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKD 1057
Score = 73.3 bits (172), Expect = 3e-12
Identities = 116/536 (21%), Positives = 233/536 (43%), Gaps = 43/536 (8%)
Query: 140 LDETMPIENIIKYPKTNLTVNQDQTDG--DILEHLSRYND-QGFELCGALRELKTQAEDA 196
L+E ++ + +T + QDQ D L+ R D + L L + K +D
Sbjct: 683 LEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDL 742
Query: 197 VNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID-EIRELR-SESENTKA 254
+ + R L A+ AL EV+ Q+++ D E++ LR S E TK
Sbjct: 743 LIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKN 802
Query: 255 LEEM--RHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
+E + R E+ A ++ KL E++ Q R+ ++++++ + + I L G
Sbjct: 803 VEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSE--ELERRVAQLQRQIEDLKG--- 857
Query: 313 MLEDQSRQKEV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
D+++ KE + E R+L E+L + + R +L+ E+ + + + T +
Sbjct: 858 ---DEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQE 914
Query: 371 HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKS 430
K QL E LK+ EQ E +R LK E E IE+LQ ++ ++ ++
Sbjct: 915 QK----QLSEKLKEE----SEQKEQLRR---LKNEMENERWHLGKTIEKLQKEMADIVEA 963
Query: 431 KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE 490
L + ++D + E + + + T + EK + +Q ++ L +EE
Sbjct: 964 SRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR---LMEEE 1020
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
+ + Q L K L EQ ++DL+ ++ ++ + + Q ++ ++
Sbjct: 1021 LRDYQRAQDEALTKRQLL--------EQTLKDLEYELEAKSHLKDDRSRLVKQ-MEDKVS 1071
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK--IREELINVLKNKETEQ 608
L+M+L + + ++ LSE +++ +++EQ +N Q R + + + I++ + + +
Sbjct: 1072 QLEMELEEERNNSDLLSERISRSREQMEQL-RNELLQERAARQDLECDKISLERQNKDLK 1130
Query: 609 SRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
SR + + +V ++ +IA D ++ N Q RLE+ V L
Sbjct: 1131 SRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKEL 1186
Score = 64.1 bits (149), Expect = 2e-09
Identities = 108/496 (21%), Positives = 213/496 (42%), Gaps = 64/496 (12%)
Query: 158 TVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA- 216
T QDQ ++ L + ++ +L G EL+ + + DL + TL
Sbjct: 812 TSEQDQAGTEMRVKLLQEENE--KLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKY 869
Query: 217 ------VGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAK 269
+ EALV + ++ V R + +E+ + S+ T+ +++ +L EE K
Sbjct: 870 EGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQK 929
Query: 270 LAIKEKLTTTESQLRQTRNRVAKMDKQLRE-AEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ E++ + K+ K++ + EAS TS L++ + +L
Sbjct: 930 EQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEM 989
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
R+L+E KT E S+L K Q E ++ + Q +D TKR
Sbjct: 990 QRQLKE--KTLEAEKSRLTAM-----------KMQDEMRLMEEELRDYQRAQDEALTKRQ 1036
Query: 389 LQEQCEITKREIELKERTETELQDSRNA-IEELQAKI----IELEKSKPNPDLPTEREID 443
L EQ T +++E + ++ L+D R+ +++++ K+ +ELE+ + N DL +ER
Sbjct: 1037 LLEQ---TLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISR 1093
Query: 444 LWAELQATKETL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
+++ + L R ++ K E +NK L + +++ E G +
Sbjct: 1094 SREQMEQLRNELLQERAARQDLECDKISLERQNK-----DLKSRIIHLE---GSYRSSKE 1145
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
L+ + E ++ + E L++ R AN Q +S + L++++ +L M++ D
Sbjct: 1146 GLVVQM---EARIAELEDR---LESEERDRANLQ-----LSNRRLERKVKELVMQVDD-- 1192
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
E L+ DQ+ +Q + R ++ EE I+ L++ + + REL E
Sbjct: 1193 -------EHLSLTDQK-DQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNE 1244
Query: 621 HRMRIVDEVNKQIAAK 636
H ++ + K + K
Sbjct: 1245 HLQGQLNSMKKDLRLK 1260
Score = 62.1 bits (144), Expect = 6e-09
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 13/232 (5%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L + + L ++E ++ + D+ L + E+ + EM EL+EER + E+++
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEM--ELEEERNNSDLLSERISR 1093
Query: 279 TESQLRQTRN-----RVAKMDKQLREA--EASITSLTGTVKMLEDQSRQKE----VQLEA 327
+ Q+ Q RN R A+ D + + E L + LE R + VQ+EA
Sbjct: 1094 SREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEA 1153
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
R +L + L++ E + L L+ +V E Q++ + QL LK KR
Sbjct: 1154 RIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKR 1213
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
++E E R K++ + EL++ + E LQ ++ ++K LP++
Sbjct: 1214 QVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSK 1265
Score = 53.6 bits (123), Expect = 2e-06
Identities = 70/352 (19%), Positives = 159/352 (45%), Gaps = 28/352 (7%)
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
++LK+ ++Q Q + +EV + +Q KLT++ +QL+ ++K + +E+
Sbjct: 586 QTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERE 645
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNP-DLPTEREIDLWAELQATK 452
+ EL+ + +++++ + L+ EL K+ + ERE E++ +
Sbjct: 646 RMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMERE-QHQTEIRDLQ 704
Query: 453 ETLRVTEDEVTTCKREKESENKIGIQQKLAAE------LLNKEEIIGKMQIQTRELI--- 503
+ L DE+ + KR ++ E I++ L A+ L+ KEE ++ + REL
Sbjct: 705 DQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 764
Query: 504 ----KNIKLNEQKVIQY-EQYVRDLQAHNRTI----ANCQESPNGISYQDLQQEIMDLKM 554
+ + ++Q++ + EQY +LQA ++ N + + + + Q ++++
Sbjct: 765 GALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRV 824
Query: 555 KLLD-----VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN---KET 606
KLL + R+EEL +A+ +++E + +K E I L+
Sbjct: 825 KLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHAR 884
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ +E + ++ LE+ + Q + ++ E +++Q+ RL+
Sbjct: 885 KEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLK 936
>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 76.6 bits (180), Expect = 3e-13
Identities = 105/502 (20%), Positives = 227/502 (45%), Gaps = 51/502 (10%)
Query: 204 SKRACH---ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMR 259
+ +AC+ E + L+ L EVA+L++ ++ + + ++ E E +A LEE+R
Sbjct: 599 NNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLE---VKNQQNIKEERERMRANLEELR 655
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRV--AKMDKQLREAEASITSLTGTVKMLEDQ 317
+ +E+ ++++L +E +LR+ + KM+++ + E ++ L+DQ
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTE---------IRDLQDQ 706
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+ +L++ R E + G + +L+Q + LQ ++L K++ E L +++
Sbjct: 707 LSEMHDELDSAKRS--EDREKGAL-IEELLQAKQDLQ-DLLIAKEEQEDL-------LRK 755
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
E +L K AL+E+ +E++ LKE+ + ELQ R ++EE K +E+ S+ N
Sbjct: 756 RERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSE 814
Query: 437 PTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
+ ++ + LQ E L+ +E+ +R + + +I + L + +E + K
Sbjct: 815 QDQAGTEMRVKLLQEENEKLQGRSEELE--RRVAQLQRQI---EDLKGDEAKAKETLKKY 869
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ + R+L E+ ++ + ++ + R + N E+ G + QE L K
Sbjct: 870 EGEIRQL-------EEALVHARKEEKEAVSARRALENELEAAQG-NLSQTTQEQKQLSEK 921
Query: 556 LLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAAL 615
L + + E+L + K + E E+ + K+++E+ ++++ T L
Sbjct: 922 LKEESEQKEQLRRL--KNEMENERWHLGK----TIEKLQKEMADIVEASRTSTLELQNQL 975
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXX 675
+ E R + E+ +Q+ K E ++ T Q ++ +E+ +
Sbjct: 976 DEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKR 1035
Query: 676 XXXXXKIAALEHELAAGLNRKE 697
+ LE+EL A + K+
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKD 1057
Score = 73.3 bits (172), Expect = 3e-12
Identities = 116/536 (21%), Positives = 233/536 (43%), Gaps = 43/536 (8%)
Query: 140 LDETMPIENIIKYPKTNLTVNQDQTDG--DILEHLSRYND-QGFELCGALRELKTQAEDA 196
L+E ++ + +T + QDQ D L+ R D + L L + K +D
Sbjct: 683 LEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDL 742
Query: 197 VNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID-EIRELR-SESENTKA 254
+ + R L A+ AL EV+ Q+++ D E++ LR S E TK
Sbjct: 743 LIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKN 802
Query: 255 LEEM--RHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
+E + R E+ A ++ KL E++ Q R+ ++++++ + + I L G
Sbjct: 803 VEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSE--ELERRVAQLQRQIEDLKG--- 857
Query: 313 MLEDQSRQKEV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
D+++ KE + E R+L E+L + + R +L+ E+ + + + T +
Sbjct: 858 ---DEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQE 914
Query: 371 HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKS 430
K QL E LK+ EQ E +R LK E E IE+LQ ++ ++ ++
Sbjct: 915 QK----QLSEKLKEE----SEQKEQLRR---LKNEMENERWHLGKTIEKLQKEMADIVEA 963
Query: 431 KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE 490
L + ++D + E + + + T + EK + +Q ++ L +EE
Sbjct: 964 SRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR---LMEEE 1020
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
+ + Q L K L EQ ++DL+ ++ ++ + + Q ++ ++
Sbjct: 1021 LRDYQRAQDEALTKRQLL--------EQTLKDLEYELEAKSHLKDDRSRLVKQ-MEDKVS 1071
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK--IREELINVLKNKETEQ 608
L+M+L + + ++ LSE +++ +++EQ +N Q R + + + I++ + + +
Sbjct: 1072 QLEMELEEERNNSDLLSERISRSREQMEQL-RNELLQERAARQDLECDKISLERQNKDLK 1130
Query: 609 SRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
SR + + +V ++ +IA D ++ N Q RLE+ V L
Sbjct: 1131 SRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKEL 1186
Score = 64.1 bits (149), Expect = 2e-09
Identities = 108/496 (21%), Positives = 213/496 (42%), Gaps = 64/496 (12%)
Query: 158 TVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA- 216
T QDQ ++ L + ++ +L G EL+ + + DL + TL
Sbjct: 812 TSEQDQAGTEMRVKLLQEENE--KLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKY 869
Query: 217 ------VGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAK 269
+ EALV + ++ V R + +E+ + S+ T+ +++ +L EE K
Sbjct: 870 EGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQK 929
Query: 270 LAIKEKLTTTESQLRQTRNRVAKMDKQLRE-AEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ E++ + K+ K++ + EAS TS L++ + +L
Sbjct: 930 EQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEM 989
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
R+L+E KT E S+L K Q E ++ + Q +D TKR
Sbjct: 990 QRQLKE--KTLEAEKSRLTAM-----------KMQDEMRLMEEELRDYQRAQDEALTKRQ 1036
Query: 389 LQEQCEITKREIELKERTETELQDSRNA-IEELQAKI----IELEKSKPNPDLPTEREID 443
L EQ T +++E + ++ L+D R+ +++++ K+ +ELE+ + N DL +ER
Sbjct: 1037 LLEQ---TLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISR 1093
Query: 444 LWAELQATKETL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
+++ + L R ++ K E +NK L + +++ E G +
Sbjct: 1094 SREQMEQLRNELLQERAARQDLECDKISLERQNK-----DLKSRIIHLE---GSYRSSKE 1145
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
L+ + E ++ + E L++ R AN Q +S + L++++ +L M++ D
Sbjct: 1146 GLVVQM---EARIAELEDR---LESEERDRANLQ-----LSNRRLERKVKELVMQVDD-- 1192
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
E L+ DQ+ +Q + R ++ EE I+ L++ + + REL E
Sbjct: 1193 -------EHLSLTDQK-DQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNE 1244
Query: 621 HRMRIVDEVNKQIAAK 636
H ++ + K + K
Sbjct: 1245 HLQGQLNSMKKDLRLK 1260
Score = 62.1 bits (144), Expect = 6e-09
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 13/232 (5%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L + + L ++E ++ + D+ L + E+ + EM EL+EER + E+++
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEM--ELEEERNNSDLLSERISR 1093
Query: 279 TESQLRQTRN-----RVAKMDKQLREA--EASITSLTGTVKMLEDQSRQKE----VQLEA 327
+ Q+ Q RN R A+ D + + E L + LE R + VQ+EA
Sbjct: 1094 SREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEA 1153
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
R +L + L++ E + L L+ +V E Q++ + QL LK KR
Sbjct: 1154 RIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKR 1213
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
++E E R K++ + EL++ + E LQ ++ ++K LP++
Sbjct: 1214 QVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSK 1265
Score = 53.6 bits (123), Expect = 2e-06
Identities = 70/352 (19%), Positives = 159/352 (45%), Gaps = 28/352 (7%)
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
++LK+ ++Q Q + +EV + +Q KLT++ +QL+ ++K + +E+
Sbjct: 586 QTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERE 645
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNP-DLPTEREIDLWAELQATK 452
+ EL+ + +++++ + L+ EL K+ + ERE E++ +
Sbjct: 646 RMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMERE-QHQTEIRDLQ 704
Query: 453 ETLRVTEDEVTTCKREKESENKIGIQQKLAAE------LLNKEEIIGKMQIQTRELI--- 503
+ L DE+ + KR ++ E I++ L A+ L+ KEE ++ + REL
Sbjct: 705 DQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 764
Query: 504 ----KNIKLNEQKVIQY-EQYVRDLQAHNRTI----ANCQESPNGISYQDLQQEIMDLKM 554
+ + ++Q++ + EQY +LQA ++ N + + + + Q ++++
Sbjct: 765 GALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRV 824
Query: 555 KLLD-----VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN---KET 606
KLL + R+EEL +A+ +++E + +K E I L+
Sbjct: 825 KLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHAR 884
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ +E + ++ LE+ + Q + ++ E +++Q+ RL+
Sbjct: 885 KEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLK 936
>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 76.6 bits (180), Expect = 3e-13
Identities = 105/502 (20%), Positives = 227/502 (45%), Gaps = 51/502 (10%)
Query: 204 SKRACH---ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMR 259
+ +AC+ E + L+ L EVA+L++ ++ + + ++ E E +A LEE+R
Sbjct: 599 NNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLE---VKNQQNIKEERERMRANLEELR 655
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRV--AKMDKQLREAEASITSLTGTVKMLEDQ 317
+ +E+ ++++L +E +LR+ + KM+++ + E ++ L+DQ
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTE---------IRDLQDQ 706
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+ +L++ R E + G + +L+Q + LQ ++L K++ E L +++
Sbjct: 707 LSEMHDELDSAKRS--EDREKGAL-IEELLQAKQDLQ-DLLIAKEEQEDL-------LRK 755
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
E +L K AL+E+ +E++ LKE+ + ELQ R ++EE K +E+ S+ N
Sbjct: 756 RERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSE 814
Query: 437 PTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
+ ++ + LQ E L+ +E+ +R + + +I + L + +E + K
Sbjct: 815 QDQAGTEMRVKLLQEENEKLQGRSEELE--RRVAQLQRQI---EDLKGDEAKAKETLKKY 869
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ + R+L E+ ++ + ++ + R + N E+ G + QE L K
Sbjct: 870 EGEIRQL-------EEALVHARKEEKEAVSARRALENELEAAQG-NLSQTTQEQKQLSEK 921
Query: 556 LLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAAL 615
L + + E+L + K + E E+ + K+++E+ ++++ T L
Sbjct: 922 LKEESEQKEQLRRL--KNEMENERWHLGK----TIEKLQKEMADIVEASRTSTLELQNQL 975
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXX 675
+ E R + E+ +Q+ K E ++ T Q ++ +E+ +
Sbjct: 976 DEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKR 1035
Query: 676 XXXXXKIAALEHELAAGLNRKE 697
+ LE+EL A + K+
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKD 1057
Score = 73.3 bits (172), Expect = 3e-12
Identities = 116/536 (21%), Positives = 233/536 (43%), Gaps = 43/536 (8%)
Query: 140 LDETMPIENIIKYPKTNLTVNQDQTDG--DILEHLSRYND-QGFELCGALRELKTQAEDA 196
L+E ++ + +T + QDQ D L+ R D + L L + K +D
Sbjct: 683 LEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDL 742
Query: 197 VNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID-EIRELR-SESENTKA 254
+ + R L A+ AL EV+ Q+++ D E++ LR S E TK
Sbjct: 743 LIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKN 802
Query: 255 LEEM--RHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
+E + R E+ A ++ KL E++ Q R+ ++++++ + + I L G
Sbjct: 803 VEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSE--ELERRVAQLQRQIEDLKG--- 857
Query: 313 MLEDQSRQKEV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
D+++ KE + E R+L E+L + + R +L+ E+ + + + T +
Sbjct: 858 ---DEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQE 914
Query: 371 HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKS 430
K QL E LK+ EQ E +R LK E E IE+LQ ++ ++ ++
Sbjct: 915 QK----QLSEKLKEE----SEQKEQLRR---LKNEMENERWHLGKTIEKLQKEMADIVEA 963
Query: 431 KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE 490
L + ++D + E + + + T + EK + +Q ++ L +EE
Sbjct: 964 SRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR---LMEEE 1020
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
+ + Q L K L EQ ++DL+ ++ ++ + + Q ++ ++
Sbjct: 1021 LRDYQRAQDEALTKRQLL--------EQTLKDLEYELEAKSHLKDDRSRLVKQ-MEDKVS 1071
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK--IREELINVLKNKETEQ 608
L+M+L + + ++ LSE +++ +++EQ +N Q R + + + I++ + + +
Sbjct: 1072 QLEMELEEERNNSDLLSERISRSREQMEQL-RNELLQERAARQDLECDKISLERQNKDLK 1130
Query: 609 SRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
SR + + +V ++ +IA D ++ N Q RLE+ V L
Sbjct: 1131 SRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKEL 1186
Score = 64.1 bits (149), Expect = 2e-09
Identities = 108/496 (21%), Positives = 213/496 (42%), Gaps = 64/496 (12%)
Query: 158 TVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA- 216
T QDQ ++ L + ++ +L G EL+ + + DL + TL
Sbjct: 812 TSEQDQAGTEMRVKLLQEENE--KLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKY 869
Query: 217 ------VGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAK 269
+ EALV + ++ V R + +E+ + S+ T+ +++ +L EE K
Sbjct: 870 EGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQK 929
Query: 270 LAIKEKLTTTESQLRQTRNRVAKMDKQLRE-AEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ E++ + K+ K++ + EAS TS L++ + +L
Sbjct: 930 EQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEM 989
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
R+L+E KT E S+L K Q E ++ + Q +D TKR
Sbjct: 990 QRQLKE--KTLEAEKSRLTAM-----------KMQDEMRLMEEELRDYQRAQDEALTKRQ 1036
Query: 389 LQEQCEITKREIELKERTETELQDSRNA-IEELQAKI----IELEKSKPNPDLPTEREID 443
L EQ T +++E + ++ L+D R+ +++++ K+ +ELE+ + N DL +ER
Sbjct: 1037 LLEQ---TLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISR 1093
Query: 444 LWAELQATKETL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
+++ + L R ++ K E +NK L + +++ E G +
Sbjct: 1094 SREQMEQLRNELLQERAARQDLECDKISLERQNK-----DLKSRIIHLE---GSYRSSKE 1145
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
L+ + E ++ + E L++ R AN Q +S + L++++ +L M++ D
Sbjct: 1146 GLVVQM---EARIAELEDR---LESEERDRANLQ-----LSNRRLERKVKELVMQVDD-- 1192
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
E L+ DQ+ +Q + R ++ EE I+ L++ + + REL E
Sbjct: 1193 -------EHLSLTDQK-DQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNE 1244
Query: 621 HRMRIVDEVNKQIAAK 636
H ++ + K + K
Sbjct: 1245 HLQGQLNSMKKDLRLK 1260
Score = 62.1 bits (144), Expect = 6e-09
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 13/232 (5%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L + + L ++E ++ + D+ L + E+ + EM EL+EER + E+++
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEM--ELEEERNNSDLLSERISR 1093
Query: 279 TESQLRQTRN-----RVAKMDKQLREA--EASITSLTGTVKMLEDQSRQKE----VQLEA 327
+ Q+ Q RN R A+ D + + E L + LE R + VQ+EA
Sbjct: 1094 SREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEA 1153
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
R +L + L++ E + L L+ +V E Q++ + QL LK KR
Sbjct: 1154 RIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKR 1213
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
++E E R K++ + EL++ + E LQ ++ ++K LP++
Sbjct: 1214 QVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSK 1265
Score = 53.6 bits (123), Expect = 2e-06
Identities = 70/352 (19%), Positives = 159/352 (45%), Gaps = 28/352 (7%)
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
++LK+ ++Q Q + +EV + +Q KLT++ +QL+ ++K + +E+
Sbjct: 586 QTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERE 645
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNP-DLPTEREIDLWAELQATK 452
+ EL+ + +++++ + L+ EL K+ + ERE E++ +
Sbjct: 646 RMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMERE-QHQTEIRDLQ 704
Query: 453 ETLRVTEDEVTTCKREKESENKIGIQQKLAAE------LLNKEEIIGKMQIQTRELI--- 503
+ L DE+ + KR ++ E I++ L A+ L+ KEE ++ + REL
Sbjct: 705 DQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 764
Query: 504 ----KNIKLNEQKVIQY-EQYVRDLQAHNRTI----ANCQESPNGISYQDLQQEIMDLKM 554
+ + ++Q++ + EQY +LQA ++ N + + + + Q ++++
Sbjct: 765 GALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRV 824
Query: 555 KLLD-----VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN---KET 606
KLL + R+EEL +A+ +++E + +K E I L+
Sbjct: 825 KLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHAR 884
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ +E + ++ LE+ + Q + ++ E +++Q+ RL+
Sbjct: 885 KEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLK 936
>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
Length = 1302
Score = 76.6 bits (180), Expect = 3e-13
Identities = 105/502 (20%), Positives = 227/502 (45%), Gaps = 51/502 (10%)
Query: 204 SKRACH---ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMR 259
+ +AC+ E + L+ L EVA+L++ ++ + + ++ E E +A LEE+R
Sbjct: 599 NNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLE---VKNQQNIKEERERMRANLEELR 655
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRV--AKMDKQLREAEASITSLTGTVKMLEDQ 317
+ +E+ ++++L +E +LR+ + KM+++ + E ++ L+DQ
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTE---------IRDLQDQ 706
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+ +L++ R E + G + +L+Q + LQ ++L K++ E L +++
Sbjct: 707 LSEMHDELDSAKRS--EDREKGAL-IEELLQAKQDLQ-DLLIAKEEQEDL-------LRK 755
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
E +L K AL+E+ +E++ LKE+ + ELQ R ++EE K +E+ S+ N
Sbjct: 756 RERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSE 814
Query: 437 PTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
+ ++ + LQ E L+ +E+ +R + + +I + L + +E + K
Sbjct: 815 QDQAGTEMRVKLLQEENEKLQGRSEELE--RRVAQLQRQI---EDLKGDEAKAKETLKKY 869
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ + R+L E+ ++ + ++ + R + N E+ G + QE L K
Sbjct: 870 EGEIRQL-------EEALVHARKEEKEAVSARRALENELEAAQG-NLSQTTQEQKQLSEK 921
Query: 556 LLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAAL 615
L + + E+L + K + E E+ + K+++E+ ++++ T L
Sbjct: 922 LKEESEQKEQLRRL--KNEMENERWHLGK----TIEKLQKEMADIVEASRTSTLELQNQL 975
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXX 675
+ E R + E+ +Q+ K E ++ T Q ++ +E+ +
Sbjct: 976 DEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKR 1035
Query: 676 XXXXXKIAALEHELAAGLNRKE 697
+ LE+EL A + K+
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKD 1057
Score = 73.3 bits (172), Expect = 3e-12
Identities = 116/536 (21%), Positives = 233/536 (43%), Gaps = 43/536 (8%)
Query: 140 LDETMPIENIIKYPKTNLTVNQDQTDG--DILEHLSRYND-QGFELCGALRELKTQAEDA 196
L+E ++ + +T + QDQ D L+ R D + L L + K +D
Sbjct: 683 LEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDL 742
Query: 197 VNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID-EIRELR-SESENTKA 254
+ + R L A+ AL EV+ Q+++ D E++ LR S E TK
Sbjct: 743 LIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKN 802
Query: 255 LEEM--RHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
+E + R E+ A ++ KL E++ Q R+ ++++++ + + I L G
Sbjct: 803 VEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSE--ELERRVAQLQRQIEDLKG--- 857
Query: 313 MLEDQSRQKEV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
D+++ KE + E R+L E+L + + R +L+ E+ + + + T +
Sbjct: 858 ---DEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQE 914
Query: 371 HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKS 430
K QL E LK+ EQ E +R LK E E IE+LQ ++ ++ ++
Sbjct: 915 QK----QLSEKLKEE----SEQKEQLRR---LKNEMENERWHLGKTIEKLQKEMADIVEA 963
Query: 431 KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE 490
L + ++D + E + + + T + EK + +Q ++ L +EE
Sbjct: 964 SRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMR---LMEEE 1020
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
+ + Q L K L EQ ++DL+ ++ ++ + + Q ++ ++
Sbjct: 1021 LRDYQRAQDEALTKRQLL--------EQTLKDLEYELEAKSHLKDDRSRLVKQ-MEDKVS 1071
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK--IREELINVLKNKETEQ 608
L+M+L + + ++ LSE +++ +++EQ +N Q R + + + I++ + + +
Sbjct: 1072 QLEMELEEERNNSDLLSERISRSREQMEQL-RNELLQERAARQDLECDKISLERQNKDLK 1130
Query: 609 SRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
SR + + +V ++ +IA D ++ N Q RLE+ V L
Sbjct: 1131 SRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKEL 1186
Score = 64.1 bits (149), Expect = 2e-09
Identities = 108/496 (21%), Positives = 213/496 (42%), Gaps = 64/496 (12%)
Query: 158 TVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA- 216
T QDQ ++ L + ++ +L G EL+ + + DL + TL
Sbjct: 812 TSEQDQAGTEMRVKLLQEENE--KLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKY 869
Query: 217 ------VGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAK 269
+ EALV + ++ V R + +E+ + S+ T+ +++ +L EE K
Sbjct: 870 EGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQK 929
Query: 270 LAIKEKLTTTESQLRQTRNRVAKMDKQLRE-AEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ E++ + K+ K++ + EAS TS L++ + +L
Sbjct: 930 EQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEM 989
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
R+L+E KT E S+L K Q E ++ + Q +D TKR
Sbjct: 990 QRQLKE--KTLEAEKSRLTAM-----------KMQDEMRLMEEELRDYQRAQDEALTKRQ 1036
Query: 389 LQEQCEITKREIELKERTETELQDSRNA-IEELQAKI----IELEKSKPNPDLPTEREID 443
L EQ T +++E + ++ L+D R+ +++++ K+ +ELE+ + N DL +ER
Sbjct: 1037 LLEQ---TLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISR 1093
Query: 444 LWAELQATKETL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
+++ + L R ++ K E +NK L + +++ E G +
Sbjct: 1094 SREQMEQLRNELLQERAARQDLECDKISLERQNK-----DLKSRIIHLE---GSYRSSKE 1145
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
L+ + E ++ + E L++ R AN Q +S + L++++ +L M++ D
Sbjct: 1146 GLVVQM---EARIAELEDR---LESEERDRANLQ-----LSNRRLERKVKELVMQVDD-- 1192
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
E L+ DQ+ +Q + R ++ EE I+ L++ + + REL E
Sbjct: 1193 -------EHLSLTDQK-DQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNE 1244
Query: 621 HRMRIVDEVNKQIAAK 636
H ++ + K + K
Sbjct: 1245 HLQGQLNSMKKDLRLK 1260
Score = 62.1 bits (144), Expect = 6e-09
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 13/232 (5%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L + + L ++E ++ + D+ L + E+ + EM EL+EER + E+++
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEM--ELEEERNNSDLLSERISR 1093
Query: 279 TESQLRQTRN-----RVAKMDKQLREA--EASITSLTGTVKMLEDQSRQKE----VQLEA 327
+ Q+ Q RN R A+ D + + E L + LE R + VQ+EA
Sbjct: 1094 SREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEA 1153
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
R +L + L++ E + L L+ +V E Q++ + QL LK KR
Sbjct: 1154 RIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKR 1213
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
++E E R K++ + EL++ + E LQ ++ ++K LP++
Sbjct: 1214 QVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSK 1265
Score = 53.6 bits (123), Expect = 2e-06
Identities = 70/352 (19%), Positives = 159/352 (45%), Gaps = 28/352 (7%)
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
++LK+ ++Q Q + +EV + +Q KLT++ +QL+ ++K + +E+
Sbjct: 586 QTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERE 645
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNP-DLPTEREIDLWAELQATK 452
+ EL+ + +++++ + L+ EL K+ + ERE E++ +
Sbjct: 646 RMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMERE-QHQTEIRDLQ 704
Query: 453 ETLRVTEDEVTTCKREKESENKIGIQQKLAAE------LLNKEEIIGKMQIQTRELI--- 503
+ L DE+ + KR ++ E I++ L A+ L+ KEE ++ + REL
Sbjct: 705 DQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 764
Query: 504 ----KNIKLNEQKVIQY-EQYVRDLQAHNRTI----ANCQESPNGISYQDLQQEIMDLKM 554
+ + ++Q++ + EQY +LQA ++ N + + + + Q ++++
Sbjct: 765 GALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRV 824
Query: 555 KLLD-----VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN---KET 606
KLL + R+EEL +A+ +++E + +K E I L+
Sbjct: 825 KLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHAR 884
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ +E + ++ LE+ + Q + ++ E +++Q+ RL+
Sbjct: 885 KEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLK 936
>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
Length = 1047
Score = 76.6 bits (180), Expect = 3e-13
Identities = 105/502 (20%), Positives = 227/502 (45%), Gaps = 51/502 (10%)
Query: 204 SKRACH---ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMR 259
+ +AC+ E + L+ L EVA+L++ ++ + + ++ E E +A LEE+R
Sbjct: 344 NNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLE---VKNQQNIKEERERMRANLEELR 400
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRV--AKMDKQLREAEASITSLTGTVKMLEDQ 317
+ +E+ ++++L +E +LR+ + KM+++ + E ++ L+DQ
Sbjct: 401 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTE---------IRDLQDQ 451
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+ +L++ R E + G + +L+Q + LQ ++L K++ E L +++
Sbjct: 452 LSEMHDELDSAKRS--EDREKGAL-IEELLQAKQDLQ-DLLIAKEEQEDL-------LRK 500
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
E +L K AL+E+ +E++ LKE+ + ELQ R ++EE K +E+ S+ N
Sbjct: 501 RERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSE 559
Query: 437 PTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
+ ++ + LQ E L+ +E+ +R + + +I + L + +E + K
Sbjct: 560 QDQAGTEMRVKLLQEENEKLQGRSEELE--RRVAQLQRQI---EDLKGDEAKAKETLKKY 614
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ + R+L E+ ++ + ++ + R + N E+ G + QE L K
Sbjct: 615 EGEIRQL-------EEALVHARKEEKEAVSARRALENELEAAQG-NLSQTTQEQKQLSEK 666
Query: 556 LLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAAL 615
L + + E+L + K + E E+ + K+++E+ ++++ T L
Sbjct: 667 LKEESEQKEQLRRL--KNEMENERWHLGK----TIEKLQKEMADIVEASRTSTLELQNQL 720
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXX 675
+ E R + E+ +Q+ K E ++ T Q ++ +E+ +
Sbjct: 721 DEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKR 780
Query: 676 XXXXXKIAALEHELAAGLNRKE 697
+ LE+EL A + K+
Sbjct: 781 QLLEQTLKDLEYELEAKSHLKD 802
Score = 73.7 bits (173), Expect = 2e-12
Identities = 116/534 (21%), Positives = 231/534 (43%), Gaps = 46/534 (8%)
Query: 140 LDETMPIENIIKYPKTNLTVNQDQTDG--DILEHLSRYND-QGFELCGALRELKTQAEDA 196
L+E ++ + +T + QDQ D L+ R D + L L + K +D
Sbjct: 428 LEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDL 487
Query: 197 VNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID-EIRELR-SESENTKA 254
+ + R L A+ AL EV+ Q+++ D E++ LR S E TK
Sbjct: 488 LIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKN 547
Query: 255 LEEM--RHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
+E + R E+ A ++ KL E++ Q R+ ++++++ + + I L G
Sbjct: 548 VEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSE--ELERRVAQLQRQIEDLKG--- 602
Query: 313 MLEDQSRQKEV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
D+++ KE + E R+L E+L + + R +L+ E+ + + + T +
Sbjct: 603 ---DEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQE 659
Query: 371 HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKS 430
K ++L+E+ +Q ++ + + E+ L + E ++ + +E + +EL+
Sbjct: 660 QKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQ 719
Query: 431 KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE---SENKIGIQQKLAAELLN 487
RE+ + Q ++TL + +T K + E E ++ Q+ E L
Sbjct: 720 LDEYKEKNRREL-AEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALT 778
Query: 488 KEEIIGK-MQIQTRELIKNIKLNEQK---VIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
K +++ + ++ EL L + + V Q E V L+ +E N
Sbjct: 779 KRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLE------MELEEERNN---S 829
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQE-----LEQQDKNSRGQARVIKIREELI 598
DL E + + ++ V RNE L E A++D E LE+Q+K+ + +R+I +
Sbjct: 830 DLLSERISRSREQMEQV-RNELLQERAARQDLECDKISLERQNKDLK--SRIIHLEGSYR 886
Query: 599 NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE--IQELFATLENK 650
+ + + +A L+ LE R D N Q++ + E ++EL ++++
Sbjct: 887 SSKEGLVVQMEARIAELEDRLESEER--DRANLQLSNRRLERKVKELVMQVDDE 938
Score = 64.5 bits (150), Expect = 1e-09
Identities = 108/496 (21%), Positives = 213/496 (42%), Gaps = 64/496 (12%)
Query: 158 TVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA- 216
T QDQ ++ L + ++ +L G EL+ + + DL + TL
Sbjct: 557 TSEQDQAGTEMRVKLLQEENE--KLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKY 614
Query: 217 ------VGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAK 269
+ EALV + ++ V R + +E+ + S+ T+ +++ +L EE K
Sbjct: 615 EGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQK 674
Query: 270 LAIKEKLTTTESQLRQTRNRVAKMDKQLRE-AEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ E++ + K+ K++ + EAS TS L++ + +L
Sbjct: 675 EQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEM 734
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
R+L+E KT E S+L K Q E ++ + Q +D TKR
Sbjct: 735 QRQLKE--KTLEAEKSRLTAM-----------KMQDEMRLMEEELRDYQRAQDEALTKRQ 781
Query: 389 LQEQCEITKREIELKERTETELQDSRNA-IEELQAKI----IELEKSKPNPDLPTEREID 443
L EQ T +++E + ++ L+D R+ +++++ K+ +ELE+ + N DL +ER
Sbjct: 782 LLEQ---TLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISR 838
Query: 444 LWAELQATKETL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
+++ + L R ++ K E +NK L + +++ E G +
Sbjct: 839 SREQMEQVRNELLQERAARQDLECDKISLERQNK-----DLKSRIIHLE---GSYRSSKE 890
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
L+ + E ++ + E L++ R AN Q +S + L++++ +L M++ D
Sbjct: 891 GLVVQM---EARIAELEDR---LESEERDRANLQ-----LSNRRLERKVKELVMQVDD-- 937
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
E L+ DQ+ +Q + R ++ EE I+ L++ + + REL E
Sbjct: 938 -------EHLSLTDQK-DQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNE 989
Query: 621 HRMRIVDEVNKQIAAK 636
H ++ + K + K
Sbjct: 990 HLQGQLNSMKKDLRLK 1005
Score = 62.5 bits (145), Expect = 5e-09
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 13/232 (5%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L + + L ++E ++ + D+ L + E+ + EM EL+EER + E+++
Sbjct: 781 QLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEM--ELEEERNNSDLLSERISR 838
Query: 279 TESQLRQTRN-----RVAKMDKQLREA--EASITSLTGTVKMLEDQSRQKE----VQLEA 327
+ Q+ Q RN R A+ D + + E L + LE R + VQ+EA
Sbjct: 839 SREQMEQVRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEA 898
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
R +L + L++ E + L L+ +V E Q++ + QL LK KR
Sbjct: 899 RIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKR 958
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
++E E R K++ + EL++ + E LQ ++ ++K LP++
Sbjct: 959 QVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSK 1010
Score = 53.6 bits (123), Expect = 2e-06
Identities = 70/352 (19%), Positives = 159/352 (45%), Gaps = 28/352 (7%)
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
++LK+ ++Q Q + +EV + +Q KLT++ +QL+ ++K + +E+
Sbjct: 331 QTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERE 390
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNP-DLPTEREIDLWAELQATK 452
+ EL+ + +++++ + L+ EL K+ + ERE E++ +
Sbjct: 391 RMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMERE-QHQTEIRDLQ 449
Query: 453 ETLRVTEDEVTTCKREKESENKIGIQQKLAAE------LLNKEEIIGKMQIQTRELI--- 503
+ L DE+ + KR ++ E I++ L A+ L+ KEE ++ + REL
Sbjct: 450 DQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALK 509
Query: 504 ----KNIKLNEQKVIQY-EQYVRDLQAHNRTI----ANCQESPNGISYQDLQQEIMDLKM 554
+ + ++Q++ + EQY +LQA ++ N + + + + Q ++++
Sbjct: 510 GALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRV 569
Query: 555 KLLD-----VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN---KET 606
KLL + R+EEL +A+ +++E + +K E I L+
Sbjct: 570 KLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHAR 629
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ +E + ++ LE+ + Q + ++ E +++Q+ RL+
Sbjct: 630 KEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLK 681
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 76.2 bits (179), Expect = 4e-13
Identities = 100/440 (22%), Positives = 206/440 (46%), Gaps = 41/440 (9%)
Query: 235 RNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMD 294
+N + + I E +SE A++EM +L EERT +K+K+ E+ L + R + +D
Sbjct: 718 KNKIYESIEEAKSE-----AMKEMEKKLLEERT----LKQKV---ENLLLEAEKRCSLLD 765
Query: 295 KQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLK--TGEVTTSQLIQ- 348
L++++ I L +L + R +++E +K + LK T +V T ++ +
Sbjct: 766 CDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEK 825
Query: 349 QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTE 407
Q ++E K +EK + + Q + +K+ + L+ EQ T + +++E E
Sbjct: 826 QLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKE 885
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
E ++ +ELQ K EL+ + + L + EI L + + + + E++ + ++
Sbjct: 886 -ECEEKTKLGKELQQKKQELQDERDS--LAAQLEITL-TKADSEQLARSIAEEQYSDLEK 941
Query: 468 EKESENKIGIQQKLAA---ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQ 524
EK + ++ I++ +A EL K+ I ++ R L ++ + + ++D+Q
Sbjct: 942 EKIMK-ELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQ 1000
Query: 525 AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNS 584
+ + + S I Q +Q + + +K V +L+EI+ +K+ D +
Sbjct: 1001 EQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAV----NKLAEIMNRKEPVKRGNDTDV 1056
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
R R K +L LK++ + ++++ Q++L +E+ QIA ++ EL
Sbjct: 1057 R---RKEKENRKLHMELKSEREKLTQQMIKYQKEL-------NEMQAQIAEESQIRIELQ 1106
Query: 645 ATLENKQQQIHRLEKIVLAL 664
TL++K I +L + AL
Sbjct: 1107 MTLDSKDSDIEQLRSQLQAL 1126
Score = 68.9 bits (161), Expect = 6e-11
Identities = 100/516 (19%), Positives = 222/516 (43%), Gaps = 32/516 (6%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D LE L + N + +L+ Q ++ + S A R+T A ++++
Sbjct: 538 DQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQ-AESSKQIQQLE 596
Query: 227 KLRQDVETRNVMIDEIR-ELRSESENTK-ALEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+D++ +N +++ + +L E N + ALE R + ++ ++ E L+
Sbjct: 597 SNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLK 656
Query: 285 QTRNRVAKMDKQLREAEASITSL-----------TGTVKMLEDQSRQKEVQLEARARKLR 333
+ +AK++ + R+ + T L T +K+++ Q+E + +A +L
Sbjct: 657 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLA 716
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLE---CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
+ K E + ++ ++LE KQ++E L ++ + L+ DLKQ+++ +
Sbjct: 717 DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKIN 776
Query: 391 E---QCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSK-PNPDLPTEREIDLW 445
E Q ++ ++ L + E E Q +L+ + ++ K L E +
Sbjct: 777 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME 836
Query: 446 AELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
++ K+ + ++ + KE ++++ +Q + L K + + +++ + E K
Sbjct: 837 MKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFST--LYKTQ-VRELKEECEEKTKL 893
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
K +QK Q Q RD A I + ++ +++ DL+ + + + E
Sbjct: 894 GKELQQKK-QELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEK---EKIMKELE 949
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
+ E++A+ QEL ++D + + L N++ E + +L +Q+ L R+
Sbjct: 950 IKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLS---RL 1006
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIV 661
DE A KA ++L K Q +++L +I+
Sbjct: 1007 KDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIM 1042
Score = 49.6 bits (113), Expect = 4e-05
Identities = 67/355 (18%), Positives = 155/355 (43%), Gaps = 21/355 (5%)
Query: 317 QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQ 376
QSR+ E ++++++ L T E S +Q ++ L+ + ++EK + + I
Sbjct: 435 QSRKNE-----ESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEI- 488
Query: 377 QLEEDLKQTKRALQ-EQCEITKREIELKERTETELQDSRNA---IEELQAKIIELEKSKP 432
L + ++ R L+ E+ + + E + + + E RN + L+ ++ +L+K
Sbjct: 489 TLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQ 548
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLA--AELLNKEE 490
N + TE+ L +L T LR TE + R+ ++E+ IQQ + +L +K
Sbjct: 549 NSQISTEKVNQLQRQLDETNALLR-TESDTAARLRKTQAESSKQIQQLESNNRDLQDKNC 607
Query: 491 IIGKMQIQTRELIKNIKL---NEQKVIQY-EQYVRDLQAHNRTIANCQESPNG-ISYQDL 545
++ +++ + N++ +E++ + + + DLQ R ++ NG I +
Sbjct: 608 LLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQ--GRICGLEEDLKNGKILLAKV 665
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR-EELINVLKNK 604
+ E L+ + D+ + + + + ++Q + + + K R + + ++
Sbjct: 666 ELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESI 725
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
E +S + +++ L + +V + L L+ QQ+I+ L K
Sbjct: 726 EEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK 780
Score = 41.9 bits (94), Expect = 0.007
Identities = 55/265 (20%), Positives = 114/265 (43%), Gaps = 14/265 (5%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAED-AVNTVTDLSKRACHERRTLIAVGEALVREV 225
++ E G EL +EL+ + + A L+K + IA + E
Sbjct: 882 ELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEK 941
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
K+ +++E + +M +EL + +LEE L + KE+L +++
Sbjct: 942 EKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQE 1001
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+R+ + +A T + L+ Q+ K ++ R +E +K G T +
Sbjct: 1002 QLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNR----KEPVKRGNDTDVR 1057
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+++++ + +E K + EKLT Q + + +++L + + + E+ +I IEL+
Sbjct: 1058 R-KEKENRKLH-MELKSEREKLTQQ----MIKYQKELNEMQAQIAEESQI---RIELQMT 1108
Query: 406 TETELQDSRNAIEELQAKIIELEKS 430
+++ D +LQA I L+ S
Sbjct: 1109 LDSKDSDIEQLRSQLQALHIGLDSS 1133
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 76.2 bits (179), Expect = 4e-13
Identities = 87/437 (19%), Positives = 196/437 (44%), Gaps = 32/437 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E E+T KE+L TE++ ++ ++ + ++ +
Sbjct: 839 KIKPLLKSAETEKEMANMKEEF--EKT-----KEELAKTEAKRKELEEKMVTLMQEKNDL 891
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + ++ E DQ + ++QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 892 QLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDEC 951
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + +
Sbjct: 952 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1011
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1012 DDLQAEEDKVNTLTKAK----IKLEQQVD---DLEGSLEQEKKIRMDLERAKRKLEGDLK 1064
Query: 475 IGIQQKLAAE--LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
+ + + E +E + K + + L I+ + +Q ++ +++LQA +
Sbjct: 1065 LAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEE 1124
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-----SEILAKKDQELEQQDKNSRGQ 587
E+ S +++ DL +L ++ R EE ++I K +E E Q K R
Sbjct: 1125 EIEAERA-SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ-KMRRDL 1182
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATL 647
E L+ K + +A L + +++ R+ ++ K+ + EI +L + +
Sbjct: 1183 EEATLQHEATAATLRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239
Query: 648 ENKQQQIHRLEKIVLAL 664
E + LEK+ AL
Sbjct: 1240 ETVSKAKGNLEKMCRAL 1256
Score = 72.9 bits (171), Expect = 3e-12
Identities = 104/482 (21%), Positives = 210/482 (43%), Gaps = 23/482 (4%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 907 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 966
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 967 KVEKEKHATENKVKNLTEEMAGLD-ETIAKLT-KEKKALQEAHQQTLDDLQAEEDKVNTL 1024
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + +T + + L ++
Sbjct: 1025 TKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKL 1084
Query: 358 LECKQQIEKL--TVQHKSAI-QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ + ++ L ++ + A+ QL++ +K+ + ++E E + E + + E + D
Sbjct: 1085 KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144
Query: 415 NAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKE-TLRVTEDEVTTCKREKESE 472
+EE+ ++ E + ++ +RE + + +E TL+ T K+ +S
Sbjct: 1145 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1204
Query: 473 NKIGIQQKLAAELLNK-EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
++G Q + K E+ +M+++ +L N++ + E+ R L+ I
Sbjct: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK 1264
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+E + Q+ I DL + + + E S L +KD + Q SRG+
Sbjct: 1265 TKEE--------EQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQL---SRGKQAFT 1313
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ EEL L+ + +S ALQ + ++ ++ AKA E+Q + ++
Sbjct: 1314 QQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKA-ELQRAMSKANSEV 1372
Query: 652 QQ 653
Q
Sbjct: 1373 AQ 1374
Score = 68.9 bits (161), Expect = 6e-11
Identities = 88/458 (19%), Positives = 189/458 (41%), Gaps = 30/458 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEK 275
A+G L +++ +L+ +E I+ R R+++E ++ ++ EL+E ++E
Sbjct: 1103 ALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS--DLSRELEE---ISERLEEA 1157
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
T +Q+ + R A+ K R+ E + T L + +L + L+
Sbjct: 1158 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV 1217
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
+ E S++ + D L + + + + K + + LE+ L + K +EQ +
Sbjct: 1218 KQKLEKEKSEMKMEIDDLASNM----ETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRL 1273
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQA 450
+ R +TE + ++E + +L + K +L + E ++ A+ A
Sbjct: 1274 INDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAK-SA 1332
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
L+ + + + + E E + + + A N E + + +T + + +L E
Sbjct: 1333 LAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE 1392
Query: 511 QKVIQYEQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKL---------LDVV 560
K + Q ++D + H + A C + Q LQ E+ DL + + LD
Sbjct: 1393 AKK-KLAQRLQDAEEHVEAVNAKCASLEK--TKQRLQNEVEDLMIDVERTNAACAALDKK 1449
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
RN +ILA+ Q+ E+ + + + +KN E +L L+++ +
Sbjct: 1450 QRN--FDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENK 1507
Query: 621 HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ + + ++ +QIA I EL + +Q+ L+
Sbjct: 1508 NLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQ 1545
Score = 59.3 bits (137), Expect = 5e-08
Identities = 94/511 (18%), Positives = 219/511 (42%), Gaps = 36/511 (7%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E + + EL + +E ++ + + + + + + + TL
Sbjct: 1446 LDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFK-IKNAYEESLDQLETLKR 1504
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+ L +E++ L + + I E+++++ + E K+ E++ L+E + + K+
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKS--ELQAALEEAEASLEHEEGKI 1562
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGT-VKMLEDQSRQKEVQLEARARKLRES 335
+ +L Q ++ V D+++ E + I + ++++E + ++ +R +R
Sbjct: 1563 LRIQLELNQVKSEV---DRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619
Query: 336 LKT-GEVTTSQL-IQQRDSLQAEVLEC---KQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K G++ ++ + + + AE L Q I K T H + +EDLK+ ++
Sbjct: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679
Query: 391 EQCEITKREIELKERTETELQDSRNAIEE--LQA-KIIELEKSKPNPDLPTEREIDLWAE 447
+ + + EIE T + + SR E+ L A + ++L ++ + T+++++ +
Sbjct: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE--TD 1737
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK 507
+ + + ED + + +E K + AE L KE+ T ++ +K
Sbjct: 1738 ISQIQGEM---EDIIQEARNAEEKAKKAITDAAMMAEELKKEQ-------DTSAHLERMK 1787
Query: 508 LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS 567
N EQ V+DLQ Q L+ + +L+ ++ RN E
Sbjct: 1788 KN------LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAV 1841
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVL--KNKETEQSRELAALQQDLE-HRMR 624
+ L K ++++++ + + I ++L++ L K K ++ E A Q ++ + R
Sbjct: 1842 KGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFR 1901
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIH 655
+ ++ +AD + L K +++H
Sbjct: 1902 RIQHELEEAEERADIAESQVNKLRVKSREVH 1932
Score = 54.4 bits (125), Expect = 1e-06
Identities = 69/405 (17%), Positives = 177/405 (43%), Gaps = 17/405 (4%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
D + EL + +N L+ ++ +L++E++ + L + + + + + KM + L +
Sbjct: 1202 DSVAELGEQIDN---LQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALED 1258
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ I + + L + + +L+ + + L + SQL + + + ++ E
Sbjct: 1259 QLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEE 1318
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
K+Q+E+ ++ KSA+ + + L+EQ E E E K + + + + + +
Sbjct: 1319 LKRQLEE-EIKAKSALAHALQSSRHDCDLLREQYE---EEQEAKAELQRAMSKANSEVAQ 1374
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES-ENKIGIQ 478
+ K E + + +L E + L LQ +E + + + ++ K+ +N++
Sbjct: 1375 WRTK-YETDAIQRTEEL-EEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEV--- 1429
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
+ L ++ + + R K + +QK + + Q +R+++ +
Sbjct: 1430 EDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLST-ELFKI 1488
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
+Y++ ++ LK + ++ +L+E +A+ + + + K + +V + + EL
Sbjct: 1489 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKK---QVEQEKSELQ 1545
Query: 599 NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
L+ E E + + ++ EV+++IA K +EI ++
Sbjct: 1546 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQM 1590
>BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein.
Length = 703
Score = 76.2 bits (179), Expect = 4e-13
Identities = 99/440 (22%), Positives = 208/440 (47%), Gaps = 41/440 (9%)
Query: 235 RNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMD 294
+N + + I E +SE A++EM +L EERT +K+K+ E+ L + R + +D
Sbjct: 33 KNKIYESIEEAKSE-----AMKEMEKKLLEERT----LKQKV---ENLLLEAEKRCSLLD 80
Query: 295 KQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK--LRES---LKTGEVTTSQLIQ- 348
L++++ I L +L + R +++E +K L ++ ++T +V T ++ +
Sbjct: 81 CDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEK 140
Query: 349 QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTE 407
Q ++E K +EK + + Q + +K+ + L+ EQ T + +++E E
Sbjct: 141 QLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKE 200
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
E ++ +ELQ K EL+ + + L + EI L + + + + E++ + ++
Sbjct: 201 -ECEEKTKLGKELQQKKQELQDERDS--LAAQLEITL-TKADSEQLARSIAEEQYSDLEK 256
Query: 468 EKESENKIGIQQKLA---AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQ 524
EK + ++ I++ +A EL K+ I ++ R L ++ + + ++D+Q
Sbjct: 257 EKIMK-ELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQ 315
Query: 525 AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNS 584
+ + + S I Q +Q + + +K V +L+EI+ +K+ D +
Sbjct: 316 EQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAV----NKLAEIMNRKEPVKRGNDTDV 371
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
R R K +L LK++ + ++++ Q++L +E+ QIA ++ EL
Sbjct: 372 R---RKEKENRKLHMELKSEREKLTQQMIKYQKEL-------NEMQAQIAEESQIRIELQ 421
Query: 645 ATLENKQQQIHRLEKIVLAL 664
TL++K I +L + AL
Sbjct: 422 MTLDSKDSDIEQLRSQLQAL 441
Score = 56.4 bits (130), Expect = 3e-07
Identities = 72/363 (19%), Positives = 160/363 (44%), Gaps = 18/363 (4%)
Query: 307 LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE---CKQQ 363
+T +K+++ Q+E + +A +L + K E + ++ ++LE KQ+
Sbjct: 5 MTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQK 64
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQE---QCEITKREI-ELKERTETELQDSRNAIEE 419
+E L ++ + L+ DLKQ+++ + E Q ++ ++ L + E E Q +
Sbjct: 65 VENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQND 124
Query: 420 LQAKIIELEKSK-PNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
L+ + ++ K L E + ++ K+ + ++ + KE ++++ +
Sbjct: 125 LKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAE 184
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
Q + L K + + +++ + E K K +QK Q Q RD A I +
Sbjct: 185 QYFST--LYKTQ-VRELKEECEEKTKLGKELQQKK-QELQDERDSLAAQLEITLTKADSE 240
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
++ +++ DL+ + + + E+ E++A+ QEL ++D + +
Sbjct: 241 QLARSIAEEQYSDLEK---EKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDV 297
Query: 599 NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
L N++ E + +L +Q+ L R+ DE A KA ++L K Q +++L
Sbjct: 298 ANLANEKEELNNKLKDVQEQLS---RLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLA 354
Query: 659 KIV 661
+I+
Sbjct: 355 EIM 357
Score = 41.9 bits (94), Expect = 0.007
Identities = 55/265 (20%), Positives = 114/265 (43%), Gaps = 14/265 (5%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAED-AVNTVTDLSKRACHERRTLIAVGEALVREV 225
++ E G EL +EL+ + + A L+K + IA + E
Sbjct: 197 ELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEK 256
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
K+ +++E + +M +EL + +LEE L + KE+L +++
Sbjct: 257 EKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQE 316
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+R+ + +A T + L+ Q+ K ++ R +E +K G T +
Sbjct: 317 QLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNR----KEPVKRGNDTDVR 372
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+++++ + +E K + EKLT Q + + +++L + + + E+ +I IEL+
Sbjct: 373 R-KEKENRKLH-MELKSEREKLTQQ----MIKYQKELNEMQAQIAEESQI---RIELQMT 423
Query: 406 TETELQDSRNAIEELQAKIIELEKS 430
+++ D +LQA I L+ S
Sbjct: 424 LDSKDSDIEQLRSQLQALHIGLDSS 448
Score = 37.9 bits (84), Expect = 0.12
Identities = 53/233 (22%), Positives = 103/233 (44%), Gaps = 28/233 (12%)
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKREKESENKI--GIQQ-------KLAAELLNKEEI 491
EID+ +L+ +++L E E K +NKI I++ ++ +LL + +
Sbjct: 2 EIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTL 61
Query: 492 IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL---------QAHNRTIANCQESPNG-IS 541
K++ E K L + + Q +Q + +L N T+ QE+ ++
Sbjct: 62 KQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLT 121
Query: 542 YQDLQ---QEIMDLKMKLLDVVHRNEELSEI---LAKKDQELEQQDKNSRGQARVIKIRE 595
DL+ Q++ LKM + N L E+ L K++ EL ++ +++ GQ + ++ +
Sbjct: 122 QNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQL 181
Query: 596 ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
E Q RE L+++ E + ++ E+ ++ DE L A LE
Sbjct: 182 EAEQYFSTLYKTQVRE---LKEECEEKTKLGKELQQKKQELQDERDSLAAQLE 231
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 76.2 bits (179), Expect = 4e-13
Identities = 87/437 (19%), Positives = 196/437 (44%), Gaps = 32/437 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E E+T KE+L TE++ ++ ++ + ++ +
Sbjct: 839 KIKPLLKSAETEKEMANMKEEF--EKT-----KEELAKTEAKRKELEEKMVTLMQEKNDL 891
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + ++ E DQ + ++QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 892 QLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDEC 951
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + +
Sbjct: 952 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1011
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1012 DDLQAEEDKVNTLTKAK----IKLEQQVD---DLEGSLEQEKKIRMDLERAKRKLEGDLK 1064
Query: 475 IGIQQKLAAE--LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
+ + + E +E + K + + L I+ + +Q ++ +++LQA +
Sbjct: 1065 LAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEE 1124
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-----SEILAKKDQELEQQDKNSRGQ 587
E+ S +++ DL +L ++ R EE ++I K +E E Q K R
Sbjct: 1125 EIEAERA-SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ-KMRRDL 1182
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATL 647
E L+ K + +A L + +++ R+ ++ K+ + EI +L + +
Sbjct: 1183 EEATLQHEATAATLRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239
Query: 648 ENKQQQIHRLEKIVLAL 664
E + LEK+ AL
Sbjct: 1240 ETVSKAKGNLEKMCRAL 1256
Score = 70.9 bits (166), Expect = 1e-11
Identities = 103/482 (21%), Positives = 209/482 (43%), Gaps = 23/482 (4%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 907 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 966
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 967 KVEKEKHATENKVKNLTEEMAGLD-ETIAKLT-KEKKALQEAHQQTLDDLQAEEDKVNTL 1024
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + + + L ++
Sbjct: 1025 TKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKL 1084
Query: 358 LECKQQIEKL--TVQHKSAI-QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ + ++ L ++ + A+ QL++ +K+ + ++E E + E + + E + D
Sbjct: 1085 KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1144
Query: 415 NAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKE-TLRVTEDEVTTCKREKESE 472
+EE+ ++ E + ++ +RE + + +E TL+ T K+ +S
Sbjct: 1145 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1204
Query: 473 NKIGIQQKLAAELLNK-EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
++G Q + K E+ +M+++ +L N++ + E+ R L+ I
Sbjct: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK 1264
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+E + Q+ I DL + + + E S L +KD + Q SRG+
Sbjct: 1265 TKEE--------EQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQL---SRGKQAFT 1313
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ EEL L+ + +S ALQ + ++ ++ AKA E+Q + ++
Sbjct: 1314 QQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKA-ELQRAMSKANSEV 1372
Query: 652 QQ 653
Q
Sbjct: 1373 AQ 1374
Score = 68.9 bits (161), Expect = 6e-11
Identities = 88/458 (19%), Positives = 189/458 (41%), Gaps = 30/458 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEK 275
A+G L +++ +L+ +E I+ R R+++E ++ ++ EL+E ++E
Sbjct: 1103 ALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS--DLSRELEE---ISERLEEA 1157
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
T +Q+ + R A+ K R+ E + T L + +L + L+
Sbjct: 1158 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV 1217
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
+ E S++ + D L + + + + K + + LE+ L + K +EQ +
Sbjct: 1218 KQKLEKEKSEMKMEIDDLASNM----ETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRL 1273
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQA 450
+ R +TE + ++E + +L + K +L + E ++ A+ A
Sbjct: 1274 INDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAK-SA 1332
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
L+ + + + + E E + + + A N E + + +T + + +L E
Sbjct: 1333 LAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEE 1392
Query: 511 QKVIQYEQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKL---------LDVV 560
K + Q ++D + H + A C + Q LQ E+ DL + + LD
Sbjct: 1393 AKK-KLAQRLQDAEEHVEAVNAKCASLEK--TKQRLQNEVEDLMIDVERTNAACAALDKK 1449
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
RN +ILA+ Q+ E+ + + + +KN E +L L+++ +
Sbjct: 1450 QRN--FDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENK 1507
Query: 621 HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ + + ++ +QIA I EL + +Q+ L+
Sbjct: 1508 NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQ 1545
Score = 58.4 bits (135), Expect = 8e-08
Identities = 94/511 (18%), Positives = 218/511 (42%), Gaps = 36/511 (7%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E + + EL + +E ++ + + + + + + + TL
Sbjct: 1446 LDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFK-IKNAYEESLDQLETLKR 1504
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+ L +E++ L + + I E+ +++ + E K+ E++ L+E + + K+
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKS--ELQAALEEAEASLEHEEGKI 1562
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGT-VKMLEDQSRQKEVQLEARARKLRES 335
+ +L Q ++ V D+++ E + I + ++++E + ++ +R +R
Sbjct: 1563 LRIQLELNQVKSEV---DRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619
Query: 336 LKT-GEVTTSQL-IQQRDSLQAEVLEC---KQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K G++ ++ + + + AE L Q I K T H + +EDLK+ ++
Sbjct: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679
Query: 391 EQCEITKREIELKERTETELQDSRNAIEE--LQA-KIIELEKSKPNPDLPTEREIDLWAE 447
+ + + EIE T + + SR E+ L A + ++L ++ + T+++++ +
Sbjct: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE--TD 1737
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK 507
+ + + ED + + +E K + AE L KE+ T ++ +K
Sbjct: 1738 ISQIQGEM---EDIIQEARNAEEKAKKAITDAAMMAEELKKEQ-------DTSAHLERMK 1787
Query: 508 LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS 567
N EQ V+DLQ Q L+ + +L+ ++ RN E
Sbjct: 1788 KN------LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAV 1841
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVL--KNKETEQSRELAALQQDLE-HRMR 624
+ L K ++++++ + + I ++L++ L K K ++ E A Q ++ + R
Sbjct: 1842 KGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFR 1901
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIH 655
+ ++ +AD + L K +++H
Sbjct: 1902 RIQHELEEAEERADIAESQVNKLRVKSREVH 1932
Score = 55.6 bits (128), Expect = 6e-07
Identities = 69/405 (17%), Positives = 178/405 (43%), Gaps = 17/405 (4%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
D + EL + +N L+ ++ +L++E++ + L + + + + + KM + L +
Sbjct: 1202 DSVAELGEQIDN---LQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALED 1258
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ I + + L + + +L+ + + L + SQL + + + ++ E
Sbjct: 1259 QLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEE 1318
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
K+Q+E+ ++ KSA+ + + L+EQ E E E K + + + + + +
Sbjct: 1319 LKRQLEE-EIKAKSALAHALQSSRHDCDLLREQYE---EEQEAKAELQRAMSKANSEVAQ 1374
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES-ENKIGIQ 478
+ K E + + +L E + L LQ +E + + + ++ K+ +N++
Sbjct: 1375 WRTK-YETDAIQRTEEL-EEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEV--- 1429
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
+ L ++ + + R K + +QK + + Q +R+++ +
Sbjct: 1430 EDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLST-ELFKI 1488
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
+Y++ ++ LK + ++ +L+E +A+ + + + +K + +V + + EL
Sbjct: 1489 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK---QVEQEKSELQ 1545
Query: 599 NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
L+ E E + + ++ EV+++IA K +EI ++
Sbjct: 1546 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQM 1590
>AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein.
Length = 1337
Score = 76.2 bits (179), Expect = 4e-13
Identities = 100/440 (22%), Positives = 206/440 (46%), Gaps = 41/440 (9%)
Query: 235 RNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMD 294
+N + + I E +SE A++EM +L EERT +K+K+ E+ L + R + +D
Sbjct: 667 KNKIYESIEEAKSE-----AMKEMEKKLLEERT----LKQKV---ENLLLEAEKRCSLLD 714
Query: 295 KQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLK--TGEVTTSQLIQ- 348
L++++ I L +L + R +++E +K + LK T +V T ++ +
Sbjct: 715 CDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEK 774
Query: 349 QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTE 407
Q ++E K +EK + + Q + +K+ + L+ EQ T + +++E E
Sbjct: 775 QLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKE 834
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
E ++ +ELQ K EL+ + + L + EI L + + + + E++ + ++
Sbjct: 835 -ECEEKTKLGKELQQKKQELQDERDS--LAAQLEITL-TKADSEQLARSIAEEQYSDLEK 890
Query: 468 EKESENKIGIQQKLAA---ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQ 524
EK + ++ I++ +A EL K+ I ++ R L ++ + + ++D+Q
Sbjct: 891 EKIMK-ELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQ 949
Query: 525 AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNS 584
+ + + S I Q +Q + + +K V +L+EI+ +K+ D +
Sbjct: 950 EQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAV----NKLAEIMNRKEPVKRGNDTDV 1005
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
R R K +L LK++ + ++++ Q++L +E+ QIA ++ EL
Sbjct: 1006 R---RKEKENRKLHMELKSEREKLTQQMIKYQKEL-------NEMQAQIAEESQIRIELQ 1055
Query: 645 ATLENKQQQIHRLEKIVLAL 664
TL++K I +L + AL
Sbjct: 1056 MTLDSKDSDIEQLRSQLQAL 1075
Score = 68.9 bits (161), Expect = 6e-11
Identities = 100/516 (19%), Positives = 222/516 (43%), Gaps = 32/516 (6%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D LE L + N + +L+ Q ++ + S A R+T A ++++
Sbjct: 487 DQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQ-AESSKQIQQLE 545
Query: 227 KLRQDVETRNVMIDEIR-ELRSESENTK-ALEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+D++ +N +++ + +L E N + ALE R + ++ ++ E L+
Sbjct: 546 SNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLK 605
Query: 285 QTRNRVAKMDKQLREAEASITSL-----------TGTVKMLEDQSRQKEVQLEARARKLR 333
+ +AK++ + R+ + T L T +K+++ Q+E + +A +L
Sbjct: 606 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLA 665
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLE---CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
+ K E + ++ ++LE KQ++E L ++ + L+ DLKQ+++ +
Sbjct: 666 DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKIN 725
Query: 391 E---QCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSK-PNPDLPTEREIDLW 445
E Q ++ ++ L + E E Q +L+ + ++ K L E +
Sbjct: 726 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME 785
Query: 446 AELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
++ K+ + ++ + KE ++++ +Q + L K + + +++ + E K
Sbjct: 786 MKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFST--LYKTQ-VRELKEECEEKTKL 842
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
K +QK Q Q RD A I + ++ +++ DL+ + + + E
Sbjct: 843 GKELQQKK-QELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEK---EKIMKELE 898
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
+ E++A+ QEL ++D + + L N++ E + +L +Q+ L R+
Sbjct: 899 IKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLS---RL 955
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIV 661
DE A KA ++L K Q +++L +I+
Sbjct: 956 KDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIM 991
Score = 53.2 bits (122), Expect = 3e-06
Identities = 67/360 (18%), Positives = 157/360 (43%), Gaps = 17/360 (4%)
Query: 313 MLEDQSRQKEVQ-LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
+L D +E +++R ++++ L T E S +Q ++ L+ + ++EK +
Sbjct: 374 LLSDSPSCRETDSIQSRKNEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKEL 433
Query: 372 KSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTETELQDSRNA---IEELQAKIIEL 427
+ I L + ++ R L+ E+ + + E + + + E RN + L+ ++ +L
Sbjct: 434 EEEI-TLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDL 492
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLA--AEL 485
+K N + TE+ L +L T LR TE + R+ ++E+ IQQ + +L
Sbjct: 493 KKRNQNSQISTEKVNQLQRQLDETNALLR-TESDTAARLRKTQAESSKQIQQLESNNRDL 551
Query: 486 LNKEEIIGKMQIQTRELIKNIKL---NEQKVIQY-EQYVRDLQAHNRTIANCQESPNG-I 540
+K ++ +++ + N++ +E++ + + + DLQ R ++ NG I
Sbjct: 552 QDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQ--GRICGLEEDLKNGKI 609
Query: 541 SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR-EELIN 599
++ E L+ + D+ + + + + ++Q + + + K R +
Sbjct: 610 LLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK 669
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ ++ E +S + +++ L + +V + L L+ QQ+I+ L K
Sbjct: 670 IYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK 729
Score = 41.9 bits (94), Expect = 0.007
Identities = 55/265 (20%), Positives = 114/265 (43%), Gaps = 14/265 (5%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAED-AVNTVTDLSKRACHERRTLIAVGEALVREV 225
++ E G EL +EL+ + + A L+K + IA + E
Sbjct: 831 ELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEK 890
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
K+ +++E + +M +EL + +LEE L + KE+L +++
Sbjct: 891 EKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQE 950
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+R+ + +A T + L+ Q+ K ++ R +E +K G T +
Sbjct: 951 QLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNR----KEPVKRGNDTDVR 1006
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+++++ + +E K + EKLT Q + + +++L + + + E+ +I IEL+
Sbjct: 1007 R-KEKENRKLH-MELKSEREKLTQQ----MIKYQKELNEMQAQIAEESQI---RIELQMT 1057
Query: 406 TETELQDSRNAIEELQAKIIELEKS 430
+++ D +LQA I L+ S
Sbjct: 1058 LDSKDSDIEQLRSQLQALHIGLDSS 1082
>AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein.
Length = 2058
Score = 76.2 bits (179), Expect = 4e-13
Identities = 94/414 (22%), Positives = 194/414 (46%), Gaps = 48/414 (11%)
Query: 232 VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
V +M + R+ + +E+ K EE+R L EE A+ + +L+ E + +
Sbjct: 83 VTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKT 142
Query: 292 KMDKQLREA-------EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT--GEVT 342
++Q++E E + + ++ LE + +Q + + E +R+ +E++K G V
Sbjct: 143 LFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ-KEAMKAEAGPVE 201
Query: 343 TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL 402
QL+Q+ + L E LE + Q EK+ + ++ LE D++ E R IEL
Sbjct: 202 -QQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVE----------EQVSRFIEL 250
Query: 403 KERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLRVTEDE 461
++ TEL D R + L+ ++ ++ K + E E D++ E+Q ++ L+V
Sbjct: 251 EQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVP-- 308
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVR 521
+ + SE++ ++LA L K + ++ + +L ++I+ +++ + E VR
Sbjct: 309 ----RFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVR 364
Query: 522 DLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELE 578
+L+ A D Q++ D K V ELS ++ A++D
Sbjct: 365 ELEQALLVSA------------DTFQKVED--RKHFGAVEAKPELSLEVQLQAERDAIDR 410
Query: 579 QQDKNSRGQARVIKIREELINVLKNKETEQ-SRELAALQQDLEHRMRIVDEVNK 631
++ + + + ++ + REEL N KN+E +Q +L +++ R++ +++ NK
Sbjct: 411 KEKEITNLEEQLEQFREELEN--KNEEVQQLHMQLEIQKKESTTRLQELEQENK 462
Score = 69.3 bits (162), Expect = 4e-11
Identities = 114/544 (20%), Positives = 235/544 (43%), Gaps = 58/544 (10%)
Query: 134 ENALELLDETMPIENIIKYPKTNL---TVNQDQTDGDILEHLSRYNDQGFELCGALRELK 190
E LE + ET K +T L + Q Q + L+ ++ E A +L
Sbjct: 65 EKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLA 124
Query: 191 TQ---AEDAVNTVTD---LSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
+ AE ++ D L +R E+ +I E + + Q++E I E RE
Sbjct: 125 VELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERE 184
Query: 245 LRSESENTKALE--EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
L S + E + +L +E T KL +KEKL + Q + R+ + KQ++ E
Sbjct: 185 LLSRQKEAMKAEAGPVEQQLLQE-TEKL-MKEKL-EVQCQAEKVRD---DLQKQVKALEI 238
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESL-KTGEVTTSQLI---QQRDSLQAEVL 358
+ LE + + + L + + L + L K + Q I +RD Q E+
Sbjct: 239 DVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ 298
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIE 418
+ +QQ+ K+ + + + +++Q L+E+ + + KE+ + ++Q+ IE
Sbjct: 299 KLEQQL-KVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIE 357
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+L+ ++ ELE++ L + +T + ED E + E + +Q
Sbjct: 358 KLEFRVRELEQA-----------------LLVSADTFQKVEDRKHFGAVEAKPELSLEVQ 400
Query: 479 QKLAAELLN-KEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+ + ++ KE+ I ++ Q + + ++ ++V Q + + + T E
Sbjct: 401 LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQE 460
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEE------LSEILAKKDQELEQQDKNSRGQARVI 591
N + D+++ + L +K D + ++ ++I+ +K+ E++Q ++ +V
Sbjct: 461 NKLFKDDMEK--LGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNE------QVT 512
Query: 592 KIREELINVLKNKETEQSRELAA-LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
K++++L NK E+ EL L+ +E M + V + + +EI++L +E
Sbjct: 513 KLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRN---REEEIEQLNEVIEKL 569
Query: 651 QQQI 654
QQ++
Sbjct: 570 QQEL 573
Score = 59.3 bits (137), Expect = 5e-08
Identities = 83/413 (20%), Positives = 187/413 (45%), Gaps = 30/413 (7%)
Query: 174 RYNDQGFELCGALREL-KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
R +QG E A+ L K ++ + L + + TL E+ L ++
Sbjct: 1277 RIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNI 1336
Query: 233 ETRNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
+ + + E++ EL S + L+E +L E+ +K +L T+ +L T
Sbjct: 1337 QQKQSQMLEMQVELSSMKDRATELQE---QLSSEKMVVAELKSELAQTKLELETTLKAQH 1393
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
K K+L + T V +L D ++ ++R+L+ +L+ + + ++RD
Sbjct: 1394 KHLKELEAFRLEVKDKTDEVHLLNDTLASEQ----KKSRELQWALEKEKAKLGRS-EERD 1448
Query: 352 SLQAEVLECKQQIEKL-TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL 410
+ E L+ + +K +Q ++Q ++ L ++++ ++ Q + ++ ++ EL
Sbjct: 1449 KEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLEL 1508
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
Q +E + +I E+ + +RE +L A+LQ++ T + + + + KE
Sbjct: 1509 QV---LLESEKVRIREMSST-------LDRERELHAQLQSSDGTGQ-SRPPLPSEDLLKE 1557
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ ++ + ELLN+ E +QTR+ ++ + +K +Q EQ +A+
Sbjct: 1558 LQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQ-----EANTEGQ 1612
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK-KDQELEQQDK 582
E + + +DLQ+++ + + ++ + + L I+ + + QELE+++K
Sbjct: 1613 KKMHELQSKV--EDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEK 1663
Score = 51.6 bits (118), Expect = 9e-06
Identities = 85/425 (20%), Positives = 185/425 (43%), Gaps = 33/425 (7%)
Query: 72 DRQAVLEVFQNLKSLYERLNNEGISACGE--GFLP-QELILFNVADWTAQEVAQLYRDAI 128
DR+++L Q +L+ ++N I+ E P QEL+ +N+ +Q L
Sbjct: 1296 DRRSLLSEIQ---ALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQ---MLEMQVE 1349
Query: 129 ASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRE 188
SS + A EL ++ + ++ K+ L QT ++ L + EL
Sbjct: 1350 LSSMKDRATELQEQLSSEKMVVAELKSELA----QTKLELETTLKAQHKHLKEL----EA 1401
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR-ELRS 247
+ + +D + V L+ E++ + AL +E AKL + E +++++ L S
Sbjct: 1402 FRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLES 1461
Query: 248 ESENTKALE---EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+ + L E + +L E K+ + L ++QL + + R ++ L + I
Sbjct: 1462 QKQRNLQLNLLLEQQKQLLNESQQKIESQRMLY--DAQLSEEQGRNLELQVLLESEKVRI 1519
Query: 305 TSLTGTVKMLEDQSRQKEVQLEAR--ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
++ T+ D+ R+ QL++ + R L + ++ +L +Q + + ++E
Sbjct: 1520 REMSSTL----DRERELHAQLQSSDGTGQSRPPLPSEDLL-KELQKQLEEKHSRIVELLN 1574
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
+ EK + QQ+E+D + ++ LQ + E + +++++D + +EE +
Sbjct: 1575 ETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQ 1634
Query: 423 KI--IELEKSKPNPDLPTEREIDL-WAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
++ ++LE + + ++ +L E + ++ L +E TT + +QQ
Sbjct: 1635 QVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQ 1694
Query: 480 KLAAE 484
K+ E
Sbjct: 1695 KIEGE 1699
Score = 44.0 bits (99), Expect = 0.002
Identities = 85/465 (18%), Positives = 202/465 (43%), Gaps = 39/465 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
+R+L+TQ E +S + C +R + E L + KL+Q++ I + +
Sbjct: 534 IRDLETQIECL------MSDQECVKRNREEEI-EQLNEVIEKLQQELAN----IGQKTSM 582
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ S + +A + ++H+LD KLA+++++ T ++ +N + + + ++ + +
Sbjct: 583 NAHSLSEEA-DSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELF 641
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
SL + +E E + L + EV ++ D+L++ LE + +
Sbjct: 642 SLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTE-----DALKS--LENQTYFK 694
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTETELQDSRNAIEELQAKI 424
K +I LE L Q + + + E+T+ ++K+ E + E LQ KI
Sbjct: 695 SFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQE----QGQFETEMLQKKI 750
Query: 425 IELEK---SKPNPDLPTEREIDL---WAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+ L+K K L ++ +++ +A+ +T+ + + E+++G
Sbjct: 751 VNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSD 810
Query: 479 -QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
L + E + +M + +++ E+ V++ E+ + +LQ + + ++
Sbjct: 811 ISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQ---KLLEGNEKKQ 867
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEE---LSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ Q++ LK ++ H NEE +E+ A + + + + + + + + K++
Sbjct: 868 REKEKKRSPQDVEVLK-TTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQ 926
Query: 595 EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
EEL+ V + T ++L+ ++ L + + K+ + E
Sbjct: 927 EELL-VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 970
Score = 42.3 bits (95), Expect = 0.006
Identities = 67/317 (21%), Positives = 145/317 (45%), Gaps = 30/317 (9%)
Query: 357 VLEC-KQQIEKLTVQHKSAIQQLEE-DLKQTKRALQE-QCEITKREIELKERTETELQDS 413
+L C +Q+I++ V++++A++ L++ D + +Q ++ R+I LK E+E + S
Sbjct: 1270 LLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESE-KPS 1328
Query: 414 RNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+ +E +Q K ++ + + +R +L +L + K + + E+ K E E+
Sbjct: 1329 QELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETT 1388
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
K Q K EL +++ ++ + L + ++ R+LQ
Sbjct: 1389 LKA--QHKHLKEL-------EAFRLEVKDKTDEVHLLNDTLASEQKKSRELQ----WALE 1435
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV-- 590
+++ G S + ++E+ DLK L RN +L+ +L ++ Q L + + Q +
Sbjct: 1436 KEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYD 1495
Query: 591 IKIREEL-----INVLKNKETEQSRELAAL---QQDLEHRMRIVDEV--NKQIAAKADEI 640
++ EE + VL E + RE+++ +++L +++ D ++ D +
Sbjct: 1496 AQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLL 1555
Query: 641 QELFATLENKQQQIHRL 657
+EL LE K +I L
Sbjct: 1556 KELQKQLEEKHSRIVEL 1572
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 76.2 bits (179), Expect = 4e-13
Identities = 100/440 (22%), Positives = 206/440 (46%), Gaps = 41/440 (9%)
Query: 235 RNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMD 294
+N + + I E +SE A++EM +L EERT +K+K+ E+ L + R + +D
Sbjct: 758 KNKIYESIEEAKSE-----AMKEMEKKLLEERT----LKQKV---ENLLLEAEKRCSLLD 805
Query: 295 KQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLK--TGEVTTSQLIQ- 348
L++++ I L +L + R +++E +K + LK T +V T ++ +
Sbjct: 806 CDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEK 865
Query: 349 QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTE 407
Q ++E K +EK + + Q + +K+ + L+ EQ T + +++E E
Sbjct: 866 QLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKE 925
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
E ++ +ELQ K EL+ + + L + EI L + + + + E++ + ++
Sbjct: 926 -ECEEKTKLGKELQQKKQELQDERDS--LAAQLEITL-TKADSEQLARSIAEEQYSDLEK 981
Query: 468 EKESENKIGIQQKLAA---ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQ 524
EK + ++ I++ +A EL K+ I ++ R L ++ + + ++D+Q
Sbjct: 982 EKIMK-ELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQ 1040
Query: 525 AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNS 584
+ + + S I Q +Q + + +K V +L+EI+ +K+ D +
Sbjct: 1041 EQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAV----NKLAEIMNRKEPVKRGNDTDV 1096
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
R R K +L LK++ + ++++ Q++L +E+ QIA ++ EL
Sbjct: 1097 R---RKEKENRKLHMELKSEREKLTQQMIKYQKEL-------NEMQAQIAEESQIRIELQ 1146
Query: 645 ATLENKQQQIHRLEKIVLAL 664
TL++K I +L + AL
Sbjct: 1147 MTLDSKDSDIEQLRSQLQAL 1166
Score = 68.9 bits (161), Expect = 6e-11
Identities = 100/516 (19%), Positives = 222/516 (43%), Gaps = 32/516 (6%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D LE L + N + +L+ Q ++ + S A R+T A ++++
Sbjct: 578 DQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQ-AESSKQIQQLE 636
Query: 227 KLRQDVETRNVMIDEIR-ELRSESENTK-ALEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+D++ +N +++ + +L E N + ALE R + ++ ++ E L+
Sbjct: 637 SNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEEDLK 696
Query: 285 QTRNRVAKMDKQLREAEASITSL-----------TGTVKMLEDQSRQKEVQLEARARKLR 333
+ +AK++ + R+ + T L T +K+++ Q+E + +A +L
Sbjct: 697 NGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLA 756
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLE---CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
+ K E + ++ ++LE KQ++E L ++ + L+ DLKQ+++ +
Sbjct: 757 DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKIN 816
Query: 391 E---QCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSK-PNPDLPTEREIDLW 445
E Q ++ ++ L + E E Q +L+ + ++ K L E +
Sbjct: 817 ELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLME 876
Query: 446 AELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
++ K+ + ++ + KE ++++ +Q + L K + + +++ + E K
Sbjct: 877 MKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFST--LYKTQ-VRELKEECEEKTKL 933
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
K +QK Q Q RD A I + ++ +++ DL+ + + + E
Sbjct: 934 GKELQQKK-QELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEK---EKIMKELE 989
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
+ E++A+ QEL ++D + + L N++ E + +L +Q+ L R+
Sbjct: 990 IKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLS---RL 1046
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIV 661
DE A KA ++L K Q +++L +I+
Sbjct: 1047 KDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIM 1082
Score = 49.6 bits (113), Expect = 4e-05
Identities = 67/355 (18%), Positives = 155/355 (43%), Gaps = 21/355 (5%)
Query: 317 QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQ 376
QSR+ E ++++++ L T E S +Q ++ L+ + ++EK + + I
Sbjct: 475 QSRKNE-----ESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEI- 528
Query: 377 QLEEDLKQTKRALQ-EQCEITKREIELKERTETELQDSRNA---IEELQAKIIELEKSKP 432
L + ++ R L+ E+ + + E + + + E RN + L+ ++ +L+K
Sbjct: 529 TLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQ 588
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLA--AELLNKEE 490
N + TE+ L +L T LR TE + R+ ++E+ IQQ + +L +K
Sbjct: 589 NSQISTEKVNQLQRQLDETNALLR-TESDTAARLRKTQAESSKQIQQLESNNRDLQDKNC 647
Query: 491 IIGKMQIQTRELIKNIKL---NEQKVIQY-EQYVRDLQAHNRTIANCQESPNG-ISYQDL 545
++ +++ + N++ +E++ + + + DLQ R ++ NG I +
Sbjct: 648 LLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQ--GRICGLEEDLKNGKILLAKV 705
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR-EELINVLKNK 604
+ E L+ + D+ + + + + ++Q + + + K R + + ++
Sbjct: 706 ELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESI 765
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
E +S + +++ L + +V + L L+ QQ+I+ L K
Sbjct: 766 EEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLK 820
Score = 41.9 bits (94), Expect = 0.007
Identities = 55/265 (20%), Positives = 114/265 (43%), Gaps = 14/265 (5%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAED-AVNTVTDLSKRACHERRTLIAVGEALVREV 225
++ E G EL +EL+ + + A L+K + IA + E
Sbjct: 922 ELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEK 981
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
K+ +++E + +M +EL + +LEE L + KE+L +++
Sbjct: 982 EKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQE 1041
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+R+ + +A T + L+ Q+ K ++ R +E +K G T +
Sbjct: 1042 QLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNR----KEPVKRGNDTDVR 1097
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+++++ + +E K + EKLT Q + + +++L + + + E+ +I IEL+
Sbjct: 1098 R-KEKENRKLH-MELKSEREKLTQQ----MIKYQKELNEMQAQIAEESQI---RIELQMT 1148
Query: 406 TETELQDSRNAIEELQAKIIELEKS 430
+++ D +LQA I L+ S
Sbjct: 1149 LDSKDSDIEQLRSQLQALHIGLDSS 1173
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 75.8 bits (178), Expect = 5e-13
Identities = 110/558 (19%), Positives = 240/558 (43%), Gaps = 41/558 (7%)
Query: 166 GDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV 225
G+ LS ++ +L + +L+ + E ++++ R ++ + +
Sbjct: 2197 GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLE 2256
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+L+ E + ++I + ++E E K +EEM L + ++ + Q++
Sbjct: 2257 RELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQ 2316
Query: 285 QTRNRVAKMDKQL----------REAEASITSLTGT-VKMLEDQSRQKEVQLEARARKLR 333
+ + +++++DK L +AE I + T V+ML++Q ++ + A +
Sbjct: 2317 EKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGD-Q 2375
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
E +K E + I++ L+ + + + ++E + +QQL+E + L+ +
Sbjct: 2376 EIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKES-EHHADLLKGRV 2434
Query: 394 EITKREIEL----KERTETELQDSRNAIEELQAKIIELEKSKPNPDLP-----TEREIDL 444
E +RE+E+ +E E ++S+ +E L+AKI + +S +L +E+E DL
Sbjct: 2435 ENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKE-DL 2493
Query: 445 WAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
ELQ KE R++E E+ E + K +Q+ + +Q Q +EL +
Sbjct: 2494 TNELQ--KEQERISELEIINSSFENILQEK---EQEKVQMKEKSSTAMEMLQTQLKELNE 2548
Query: 505 NIKL--NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ N+Q+ + ++ Q + Q G+ + + + L+ + ++
Sbjct: 2549 RVAALHNDQEACKAKEQNLSSQVECLELEKAQ-LLQGL--DEAKNNYIVLQSSVNGLIQE 2605
Query: 563 NEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
E+ + L KKD+E+ + + Q +++ + + EQ+ EL L +LE +
Sbjct: 2606 VEDGKQKLEKKDEEISRLKNQIQDQEQLVS-KLSQVEGEHQLWKEQNLELRNLTVELEQK 2664
Query: 623 MRIVDEVNKQIAAKADEIQELFATLEN-----KQQQIHRLEKIVLALXXXXXXXXXXXXX 677
++++ N + + +Q + LEN K ++ +EK V +
Sbjct: 2665 IQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VNKMTAKETELQREMHE 2723
Query: 678 XXXKIAALEHELAAGLNR 695
K A L+ EL+ NR
Sbjct: 2724 MAQKTAELQEELSGEKNR 2741
Score = 66.9 bits (156), Expect = 2e-10
Identities = 106/542 (19%), Positives = 232/542 (42%), Gaps = 36/542 (6%)
Query: 147 ENIIKYPKTNLTVNQD--QTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLS 204
E + + ++ T++Q+ Q + + L + + L L +L + + N + +
Sbjct: 398 EELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFK 457
Query: 205 KRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS-ESENTKA-LEEMRHEL 262
++ C + A + E+ + ++++ N ++ E ++ E + +A L+ ++ L
Sbjct: 458 QKLCRAEQAFQA-SQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCL 516
Query: 263 DEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--REAEASITSLTGTVKMLEDQSRQ 320
++ + +K K T+ E+ LR + ++ + + L + + ++ L +D ++
Sbjct: 517 NQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKK 576
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQR---DSLQAE--VLEC-KQQIEKLTVQHKSA 374
+E +E KL ++ K + S L ++ + L+ E + C K + EKL Q +S
Sbjct: 577 REHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESE 636
Query: 375 IQQLEEDLKQTKRALQEQCEITKREIELKERT-----ETELQDSRNAIEELQAKIIELEK 429
+ L+ + + L+ Q +I E + RT E + RN L +K +E+E
Sbjct: 637 KENLQSKINHLETCLKTQ-QIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVET 695
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE 489
K E+ AE K + + T + + E+ Q L+ E+++K+
Sbjct: 696 QKL-----AYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKD 750
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ-DLQQE 548
+ + L +K + ++ E + R L A ++ A N I Q + E
Sbjct: 751 RCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSE 810
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK-NSRGQAR---VIKIREELI-NVLKN 603
+ +++ + L + + LE Q + NS Q + +++I+ E+ N++K
Sbjct: 811 RSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKA 870
Query: 604 KETEQS------RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
++ QS + ++ LQ+D +V E + K E+Q L +E +Q +I L
Sbjct: 871 EQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQEL 930
Query: 658 EK 659
+K
Sbjct: 931 KK 932
Score = 65.3 bits (152), Expect = 7e-10
Identities = 82/403 (20%), Positives = 176/403 (43%), Gaps = 28/403 (6%)
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
L ++Q ++ RN++ +++ +L+ E + + L+ Q + +V+L + + L +
Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKC 339
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQ---QLEEDLKQTKRALQEQ 392
TT+Q Q A + K+ E L+ Q ++A LE+ +K+ ++ QE+
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEE 399
Query: 393 CEITKRE--------IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL 444
+R I++K R ELQ ++N LQA++ +L K + E
Sbjct: 400 LSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQK 459
Query: 445 WAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ + ++ E+E+ E + EN + L + K + ++ + +K
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNL-----LKSHSEQKAREVCHLEAE----LK 510
Query: 505 NIKLNEQKVIQYEQYVRDLQAHNRTIANC-QESPNGISYQDLQQEIMDLKMKLLDVVHRN 563
NIK Q + Q + + +++A N + ++ I+ Q+ + LK+ + D+ +
Sbjct: 511 NIK---QCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQR 567
Query: 564 EELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE-H 621
+ ++L K++ +EQ DK S+ + + L LK KE E+ +E L +
Sbjct: 568 DCSQDLLKKREHHIEQLNDKLSKTEKESKALLSAL--ELKKKEYEELKEEKTLFSCWKSE 625
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
+++ ++ + +I L L+ +Q + H + V L
Sbjct: 626 NEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTL 668
Score = 58.4 bits (135), Expect = 8e-08
Identities = 86/363 (23%), Positives = 158/363 (43%), Gaps = 29/363 (7%)
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
+ S+ S ++ DQS + L+ R L SL++ + S L +Q + L E
Sbjct: 804 QGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEI 863
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
++ + K H+S + + + + + + + + E E ELQ + +E
Sbjct: 864 EENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETE 923
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC----KRE-KESENKI 475
QA+I EL+KS + D ELQ ETL + + E+++ KRE +E +
Sbjct: 924 QAEIQELKKSNHLLE-------DSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 976
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G +++ A LN+E++ IQ E N +K I E + Q + C+E
Sbjct: 977 GTLKEINAS-LNQEKM---NLIQKSESFANYIDEREKSIS-ELSDQYKQEKLILLQRCEE 1031
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
+ N +Y+DL Q+ + K + E + + + ELEQ +A + +E
Sbjct: 1032 TGN--AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLK-----EAFAKEHQE 1084
Query: 596 ELINVLKNKETEQS--RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ 653
L + +E Q+ EL +QQ L R + D N ++A +++ TL+ +Q +
Sbjct: 1085 FLTKLAFAEERNQNLMLELETVQQAL--RSEMTDNQNNS-KSEAGGLKQEIMTLKEEQNK 1141
Query: 654 IHR 656
+ +
Sbjct: 1142 MQK 1144
Score = 57.2 bits (132), Expect = 2e-07
Identities = 83/436 (19%), Positives = 197/436 (45%), Gaps = 31/436 (7%)
Query: 248 ESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
E+EN+K +E ++ +++ + ++ + T S+ N + K +++ E E +S
Sbjct: 2454 EAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEIINSS 2513
Query: 307 LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
++ E + Q + + L+ LK + L +++ +A+ Q+E
Sbjct: 2514 FENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVEC 2573
Query: 367 LTVQHKSAIQQLEED------LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
L ++ +Q L+E L+ + L ++ E K+++E K+ + L++ E+L
Sbjct: 2574 LELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQL 2633
Query: 421 QAKIIEL--------EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+K+ ++ E++ +L E E + LQ+ +L+ T + + + + E+E
Sbjct: 2634 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQV-LQSKNASLQDTLEVLQSSYKNLENE 2692
Query: 473 NKIGIQQKLA-AELLNKEEI-IGKMQIQTRELI-KNIKLNEQKVIQYEQYVRDLQAHNRT 529
++ K++ E +NK ++Q + E+ K +L E+ + + +LQ
Sbjct: 2693 LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEE 2752
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK---DQELEQQDKNSRG 586
I + ++ ++L E +LK K LD +H+++ E ++ + +L + +
Sbjct: 2753 IKSSKD-----QLKELTLENSELK-KSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 2806
Query: 587 QARVI---KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
QA ++ K E I + K T + L++ + +++ +E+N + A ++EL
Sbjct: 2807 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEEL 2866
Query: 644 FATLENKQQQIHRLEK 659
T + + +++L+K
Sbjct: 2867 KKTKMDNLKYVNQLKK 2882
Score = 51.6 bits (118), Expect = 9e-06
Identities = 87/430 (20%), Positives = 180/430 (41%), Gaps = 40/430 (9%)
Query: 257 EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED 316
E R E D+ ++ ++ + E L + + + KQ E + + E
Sbjct: 813 ECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQ 872
Query: 317 QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV--LECKQQIEKLTVQHKSA 374
+ + R KL+E + ++ + ++ + E+ L K + E+ +Q
Sbjct: 873 MHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKK 932
Query: 375 IQQLEEDLKQTKRALQEQCEITKRE----IELKERTETELQDSRNAIEELQAKIIE---- 426
L ED + + L E + K+E I L +R EL ++E+ A + +
Sbjct: 933 SNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMN 992
Query: 427 -LEKSKPNPDLPTEREIDLWAEL--QATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
++KS+ + ERE + +EL Q +E L + + C+ + + + K A
Sbjct: 993 LIQKSESFANYIDEREKSI-SELSDQYKQEKLILLQ----RCEETGNAYEDLSQKYKAAQ 1047
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
E +K E + + L +N K NE + ++ E + ++ Q +A +E + +
Sbjct: 1048 EKNSKLECLLN---ECTSLCENRK-NELEQLK-EAFAKEHQEFLTKLAFAEERNQNLMLE 1102
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL---EQQDKNSRGQARVIKIREELINV 600
L+ L+ ++ D ++N SE K + + E+Q+K + +++ E+L+ V
Sbjct: 1103 -LETVQQALRSEMTD--NQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKV 1159
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVN---------KQIAAKADEIQ--ELFATLEN 649
+K K Q+ E ++ ++ R ++ N K+I+ + Q +L A L N
Sbjct: 1160 MKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRN 1219
Query: 650 KQQQIHRLEK 659
K+ ++ EK
Sbjct: 1220 KELKLQESEK 1229
Score = 46.4 bits (105), Expect = 3e-04
Identities = 59/224 (26%), Positives = 104/224 (46%), Gaps = 31/224 (13%)
Query: 224 EVAKLRQDV----ETRNVMIDEIRELRSESENTKALEEMRHELD--EERTAKLAIKEKLT 277
E L+Q++ E +N M E+ +L E+E + + +HE E + ++KE+
Sbjct: 1124 EAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKER-- 1181
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRE 334
ES+ Q N +MD +++ E S+ S + LE R KE++L+ ++ L+
Sbjct: 1182 --ESERNQC-NFKPQMDLEVK--EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQH 1236
Query: 335 SLKT--GEVTTSQLIQQRDSLQAEVLECKQQIEK--LTVQHKSAIQQ-----LEEDLKQT 385
L+T G++ TS L + + + +C+ E+ ++ H+ + Q L+ L+ T
Sbjct: 1237 ELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTT 1296
Query: 386 KRALQEQ---CEITKREIELKERTETELQDSRNAIEELQAKIIE 426
L E CEI + E K TEL DSR+ K+ E
Sbjct: 1297 MNKLNELEKICEILQAE---KYELVTELNDSRSECITATRKMAE 1337
Score = 39.5 bits (88), Expect = 0.039
Identities = 57/298 (19%), Positives = 132/298 (44%), Gaps = 27/298 (9%)
Query: 134 ENALEL--LDETMPIENIIKYPKTNLTVNQD-----QTDGDILEHLSRYNDQGFELCGAL 186
EN LEL +D+ +E + K + ++ Q ++ E LS ++ L G L
Sbjct: 2690 ENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNR---LAGEL 2746
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE-- 244
+ L + + + + + +L+ +++L + + V + K+R+++ + + E +
Sbjct: 2747 QLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 2806
Query: 245 ----LRSESENTKALEEMRHELDEER----TAKLAIKEKLTTTESQLRQTRNRVAKMDKQ 296
L + + ++ R +L + + KL I + L +++ +L + ++ ++
Sbjct: 2807 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEI-DLLKSSKEELNNSLKATTQILEE 2865
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL-IQQRDSLQA 355
L++ + +K ++++ K L ++L E + + SQL Q
Sbjct: 2866 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTG 2925
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE--ITKREIE-LKERTETEL 410
V++ K +++LT + K + LEE K+ L + C I+ ++E KE ET++
Sbjct: 2926 TVMDTK--VDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQV 2981
Score = 37.1 bits (82), Expect = 0.21
Identities = 80/436 (18%), Positives = 188/436 (43%), Gaps = 29/436 (6%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTESQ 282
E +L +E R+ ++ + E ++ L+E++ E +L I +L S
Sbjct: 1878 ENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSD 1937
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG--- 339
L + + ++L + + L ++M D+S ++++ K+ +S K
Sbjct: 1938 LSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIG--DNVAKVNDSWKERFLD 1995
Query: 340 -EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-TK 397
E S++ ++ S++ E L + +E + + K +++ E+ ++ L+E+ + T
Sbjct: 1996 VENELSRIRSEKASIEHEALYLEADLEVVQTE-KLCLEKDNENKQKVIVCLEEELSVVTS 2054
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLR 456
+L+ +T + A+++L K+ E + + I + AE++ E L+
Sbjct: 2055 ERNQLRGELDT-MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQ 2113
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI-KLNEQKVIQ 515
+V+ ++K +Q+KL + L K+ + + EL I +LN++K
Sbjct: 2114 TLSSDVSELLKDKTH-----LQEKLQS--LEKDS--QALSLTKCELENQIAQLNKEK--- 2161
Query: 516 YEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI---LAK 572
E V++ ++ ++ +S + L+ +++ L + EE+ ++ + K
Sbjct: 2162 -ELLVKESESLQARLSESDYEKLNVS-KALEAALVEKGEFALRLSSTQEEVHQLRRGIEK 2219
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ 632
+E +K A +K RE + LK+K REL +++ E + + +
Sbjct: 2220 LRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAE 2279
Query: 633 IAAKADEIQELFATLE 648
+ +I+E+ +L+
Sbjct: 2280 VETLKTQIEEMARSLK 2295
Score = 36.7 bits (81), Expect = 0.28
Identities = 56/263 (21%), Positives = 119/263 (45%), Gaps = 13/263 (4%)
Query: 232 VETRNVMIDEIRELRSES-ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
VE N M + EL+ E E + E++ EL E+ +LA + +L E ++ +++++
Sbjct: 2704 VEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKN-RLAGELQLLLEE--IKSSKDQL 2760
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
++ + E + S+ + E + R++ + + R + + + + T++ +
Sbjct: 2761 KELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVE 2820
Query: 351 DSLQAEVLECKQQI---EKLTVQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
E L K++ +KL + KS+ ++L LK T + L+E + ++ +
Sbjct: 2821 IQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQL 2880
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTE-REIDLWAELQATKETLRVTEDEVTTC 465
+ E + ++ ++ L +LE+ K L E ++ E Q T + DE+TT
Sbjct: 2881 KKENERAQGKMKLLIKSCKQLEEEK--EILQKELSQLQAAQEKQKTGTVMDTKVDELTT- 2937
Query: 466 KREKESENKIGIQQKLAAELLNK 488
KE + + + K A E L+K
Sbjct: 2938 -EIKELKETLEEKTKEADEYLDK 2959
>AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1007
Score = 75.8 bits (178), Expect = 5e-13
Identities = 115/516 (22%), Positives = 235/516 (45%), Gaps = 44/516 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE---- 241
L +LK+Q + L ++ H++ L + ++V+ A L++ + + E
Sbjct: 264 LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNH 323
Query: 242 IRELRSESENTKALE-EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
IRE++S E + E+ ++ E +T IK+++ E L+ +++K +L+
Sbjct: 324 IREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNI 383
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTT-SQLIQQRDSLQAEVL 358
+ ++ L+ Q Q+ +LE + L E L+ + SQ + Q ++L
Sbjct: 384 LDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLL 443
Query: 359 EC-KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-------TKREIELKERT---- 406
E K++IE++T + + A+Q E L + K LQE+C+I TKR + E
Sbjct: 444 ERDKREIERMTAESR-ALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKME 502
Query: 407 ETELQDSRNAIEELQAKIIELEKSK---------PNPDLPTEREI--DLWAELQATKETL 455
++ L+ + +LQ ++ +L + K L +RE L EL ++ L
Sbjct: 503 QSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHL 562
Query: 456 RVT-EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGK----MQIQTRELIKNIKLNE 510
+ +D + T K + ++ QK +E N+ E K Q Q + L I+ N+
Sbjct: 563 NLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENK 622
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEI 569
K++Q E + LQ + +ES S L+++ L+ +L D + ++ LS++
Sbjct: 623 LKLVQQEMMFQRLQKERES----EESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 678
Query: 570 LAKKD--QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
LA ++ + L+++++ + + + ++ + + E+S EL ALQ++ +
Sbjct: 679 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 738
Query: 628 EVNKQIAAKADEIQELFATL-ENKQQQIHRLEKIVL 662
+ Q + + ++ A+L E + Q +LEK +L
Sbjct: 739 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLL 774
Score = 67.3 bits (157), Expect = 2e-10
Identities = 120/570 (21%), Positives = 244/570 (42%), Gaps = 62/570 (10%)
Query: 169 LEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKL 228
++HL + + + R+ + + E+ + + DL + E+++L E L R V K
Sbjct: 1 MQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQ----EKKSLECEVEELHRTVQKR 56
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
+Q ++ + + L +E E K+L+ +DE I++ L S+LR+
Sbjct: 57 QQQ---KDFIDGNVESLMTELEIEKSLKHHEDIVDEIE----CIEKTLLKRRSELREADR 109
Query: 289 RVAKMDKQLREAEASITSLT----------GTVKMLEDQSRQKEVQLEARARKLRESLKT 338
+A+ + +L + + L V+ D R +Q E+ A +L +
Sbjct: 110 LLAEAESELSCTKEKVCLLVVWGVSSVWTKNAVEKFTDAKRSL-LQTESDAEELERRAQE 168
Query: 339 GEVTTSQLIQQRDSLQAEVLECKQ---QIEKLTVQHKSAIQQLEED---LKQTKRALQEQ 392
V + QQ SLQA+ + +Q + E++ + + + D L + K L E+
Sbjct: 169 TAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEE 228
Query: 393 CEITKREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
+ +++IE+ ER E LQ + + LQAK ELEK K + L +L
Sbjct: 229 LQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHK 288
Query: 452 KETLRVTEDEVTTCKREKESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
KE L + + + K + + ++G + + + + ++ ++ Q EL N++++
Sbjct: 289 KEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGEL--NVQIS 346
Query: 510 EQKVI------QYEQYVRDLQAHNRTIANCQ-ESPNGISYQDLQQ-EIMDLKMKLLDVVH 561
E+K + E+ +LQ R ++ + E N + L+ E+ LK++ V
Sbjct: 347 ERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVS 406
Query: 562 RNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ----- 616
E+ + ++ ELE + S+ Q I+ +++L+ K + + E ALQ
Sbjct: 407 ELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVEC 466
Query: 617 -----QDLEHRMRIVDEV---NKQIAAKADE--------IQELFATLENKQQQIHRLEKI 660
+DL+ + I ++ K++ A A+E +++L + QQ++ +L +
Sbjct: 467 LSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRD 526
Query: 661 VLALXXXXXXXXXXXXXXXXKIAALEHELA 690
L+L + +L+ ELA
Sbjct: 527 KLSLHNDISAMQQQLQEKREAVNSLQEELA 556
>AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1773
Score = 75.8 bits (178), Expect = 5e-13
Identities = 115/516 (22%), Positives = 235/516 (45%), Gaps = 44/516 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE---- 241
L +LK+Q + L ++ H++ L + ++V+ A L++ + + E
Sbjct: 1030 LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNH 1089
Query: 242 IRELRSESENTKALE-EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
IRE++S E + E+ ++ E +T IK+++ E L+ +++K +L+
Sbjct: 1090 IREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNI 1149
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTT-SQLIQQRDSLQAEVL 358
+ ++ L+ Q Q+ +LE + L E L+ + SQ + Q ++L
Sbjct: 1150 LDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLL 1209
Query: 359 EC-KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-------TKREIELKERT---- 406
E K++IE++T + + A+Q E L + K LQE+C+I TKR + E
Sbjct: 1210 ERDKREIERMTAESR-ALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKME 1268
Query: 407 ETELQDSRNAIEELQAKIIELEKSK---------PNPDLPTEREI--DLWAELQATKETL 455
++ L+ + +LQ ++ +L + K L +RE L EL ++ L
Sbjct: 1269 QSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHL 1328
Query: 456 RVT-EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGK----MQIQTRELIKNIKLNE 510
+ +D + T K + ++ QK +E N+ E K Q Q + L I+ N+
Sbjct: 1329 NLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENK 1388
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEI 569
K++Q E + LQ + +ES S L+++ L+ +L D + ++ LS++
Sbjct: 1389 LKLVQQEMMFQRLQKERES----EESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 1444
Query: 570 LAKKD--QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
LA ++ + L+++++ + + + ++ + + E+S EL ALQ++ +
Sbjct: 1445 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 1504
Query: 628 EVNKQIAAKADEIQELFATL-ENKQQQIHRLEKIVL 662
+ Q + + ++ A+L E + Q +LEK +L
Sbjct: 1505 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLL 1540
Score = 75.4 bits (177), Expect = 6e-13
Identities = 121/562 (21%), Positives = 244/562 (43%), Gaps = 55/562 (9%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
DI++HL + + + R+ + + E+ + + DL + E+++L E L R V
Sbjct: 778 DIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQ----EKKSLECEVEELHRTVQ 833
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
K +Q ++ + + L +E E K+L+ +DE I++ L S+LR+
Sbjct: 834 KRQQQ---KDFIDGNVESLMTELEIEKSLKHHEDIVDEIE----CIEKTLLKRRSELREA 886
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+A+ + +L + V+ D R +Q E+ A +L + V +
Sbjct: 887 DRLLAEAESEL---SCTKEKTKNAVEKFTDAKRSL-LQTESDAEELERRAQETAVNLVKA 942
Query: 347 IQQRDSLQAEVLECKQ---QIEKLTVQHKSAIQQLEED---LKQTKRALQEQCEITKREI 400
QQ SLQA+ + +Q + E++ + + + D L + K L E+ + +++I
Sbjct: 943 DQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDI 1002
Query: 401 ELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E+ ER E LQ + + LQAK ELEK K + L +L KE L + +
Sbjct: 1003 EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ 1062
Query: 460 DEVTTCKREKESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI--- 514
+ K + + ++G + + + + ++ ++ Q EL N++++E+K
Sbjct: 1063 GSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGEL--NVQISERKTQLTL 1120
Query: 515 ---QYEQYVRDLQAHNRTIANCQ-ESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEI 569
+ E+ +LQ R ++ + E N + L+ E+ LK++ V E+
Sbjct: 1121 IKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVA 1180
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ----------QDL 619
+ ++ ELE + S+ Q I+ +++L+ K + + E ALQ +DL
Sbjct: 1181 VLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDL 1240
Query: 620 EHRMRIVDEV---NKQIAAKADE--------IQELFATLENKQQQIHRLEKIVLALXXXX 668
+ + I ++ K++ A A+E +++L + QQ++ +L + L+L
Sbjct: 1241 QEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDI 1300
Query: 669 XXXXXXXXXXXXKIAALEHELA 690
+ +L+ ELA
Sbjct: 1301 SAMQQQLQEKREAVNSLQEELA 1322
Score = 54.8 bits (126), Expect = 1e-06
Identities = 66/286 (23%), Positives = 129/286 (45%), Gaps = 27/286 (9%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
AKL+ + N++ ++++ ++ N +R E R +L K KL T E +
Sbjct: 221 AKLKHLQDDNNLLKQQLKDFQNHL-NHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHS 279
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+ + K L + + + + K D+++ +E +L+ +E L TG+ Q
Sbjct: 280 PSD---VLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQ 336
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
++ LE + +K QH++ IQQ+E ++ LQE + + E++
Sbjct: 337 ACER-------ALEARMNFDKR--QHEARIQQMENEIHY----LQENLKSME---EIQGL 380
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTED---- 460
T+ +LQ++ E + A++ ELEK K D ++ ++ L EL+ K+ + ++
Sbjct: 381 TDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATA 440
Query: 461 EVTTCKREKES--ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
E+T K + +S + I Q+ A EL E K R+L +
Sbjct: 441 ELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTR 486
Score = 49.6 bits (113), Expect = 4e-05
Identities = 104/496 (20%), Positives = 215/496 (43%), Gaps = 47/496 (9%)
Query: 194 EDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENT 252
++ + T+ + +A +E R L E L++ + ++ Q+ + ++ + +R E +E
Sbjct: 70 QEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELE 129
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
AL+E +HE++ + + L+ E++L N QL+E +T LT
Sbjct: 130 SALQE-QHEVN---ASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLT---- 181
Query: 313 MLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHK 372
LE + Q E++ E +A L+ +L + + + Q+ L A++ + L Q K
Sbjct: 182 QLEQSALQAELEKERQA--LKNALGKAQF-SEEKEQENSELHAKLKHLQDDNNLLKQQLK 238
Query: 373 SAIQQLEEDLKQTKRALQEQCEITKREIELKERT-ETELQDSRN----AIEELQAKIIE- 426
L + R + + + +LK T E + + ++ +LQ + E
Sbjct: 239 DFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEI 298
Query: 427 LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEV-TTCKREKES-------ENKIGIQ 478
L +SK D RE L E+ +E L ++E C+R E+ +++ IQ
Sbjct: 299 LARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQ 358
Query: 479 QK------LAAELLNKEEIIG--KMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
Q L L + EEI G +Q+Q + K L + + ++ ++ + D ++ +
Sbjct: 359 QMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVF 418
Query: 531 A---NCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
++ ++ D E+ K +L + ++++ A++ QE E+ + +
Sbjct: 419 GLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAA 478
Query: 586 GQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
AR + E I +L+N Q E L+ + + + N Q+ EI++L
Sbjct: 479 QAARDLTRAEAEIELLQNL-LRQKGEQFRLEME---KTGVGTGANSQVL----EIEKLNE 530
Query: 646 TLENKQQQIHRLEKIV 661
T+E ++ +I RL+ ++
Sbjct: 531 TMERQRTEIARLQNVL 546
Score = 39.9 bits (89), Expect = 0.030
Identities = 65/335 (19%), Positives = 143/335 (42%), Gaps = 15/335 (4%)
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
+G + L+ ++Q + QLE+R L E L T ++ + L + + ++K
Sbjct: 6 SGKEQQLDIMNKQYQ-QLESR---LDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKD 61
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
S +Q+ +K Q +C + E E + TE++ R+ +E + +
Sbjct: 62 LEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENM 121
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE-NKIGIQQKLAAELL 486
K + + + ++ A LQ T+ L E E+ +++E N++ + + L
Sbjct: 122 RKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLT 181
Query: 487 NKEEIIGKMQIQ-TRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDL 545
E+ + +++ R+ +KN Q + EQ +L A + + Q+ N L
Sbjct: 182 QLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHA---KLKHLQDDNN-----LL 233
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
+Q++ D + L VV E+ A+ D EL ++ K G+ + + L L + +
Sbjct: 234 KQQLKDFQNHLNHVVDGLVRPEEVAARVD-ELRRKLKLGTGEMNIHSPSDVLGKSLADLQ 292
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI 640
+ S LA + + + ++ +++A + +++
Sbjct: 293 KQFSEILARSKWERDEAQVRERKLQEEMALQQEKL 327
>AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110kDa
protein.
Length = 2325
Score = 75.8 bits (178), Expect = 5e-13
Identities = 115/516 (22%), Positives = 235/516 (45%), Gaps = 44/516 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE---- 241
L +LK+Q + L ++ H++ L + ++V+ A L++ + + E
Sbjct: 1582 LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNH 1641
Query: 242 IRELRSESENTKALE-EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
IRE++S E + E+ ++ E +T IK+++ E L+ +++K +L+
Sbjct: 1642 IREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNI 1701
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTT-SQLIQQRDSLQAEVL 358
+ ++ L+ Q Q+ +LE + L E L+ + SQ + Q ++L
Sbjct: 1702 LDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLL 1761
Query: 359 EC-KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-------TKREIELKERT---- 406
E K++IE++T + + A+Q E L + K LQE+C+I TKR + E
Sbjct: 1762 ERDKREIERMTAESR-ALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKME 1820
Query: 407 ETELQDSRNAIEELQAKIIELEKSK---------PNPDLPTEREI--DLWAELQATKETL 455
++ L+ + +LQ ++ +L + K L +RE L EL ++ L
Sbjct: 1821 QSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHL 1880
Query: 456 RVT-EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGK----MQIQTRELIKNIKLNE 510
+ +D + T K + ++ QK +E N+ E K Q Q + L I+ N+
Sbjct: 1881 NLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENK 1940
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEI 569
K++Q E + LQ + +ES S L+++ L+ +L D + ++ LS++
Sbjct: 1941 LKLVQQEMMFQRLQKERES----EESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 1996
Query: 570 LAKKD--QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
LA ++ + L+++++ + + + ++ + + E+S EL ALQ++ +
Sbjct: 1997 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 2056
Query: 628 EVNKQIAAKADEIQELFATL-ENKQQQIHRLEKIVL 662
+ Q + + ++ A+L E + Q +LEK +L
Sbjct: 2057 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLL 2092
Score = 75.4 bits (177), Expect = 6e-13
Identities = 121/562 (21%), Positives = 244/562 (43%), Gaps = 55/562 (9%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
DI++HL + + + R+ + + E+ + + DL + E+++L E L R V
Sbjct: 1330 DIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQ----EKKSLECEVEELHRTVQ 1385
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
K +Q ++ + + L +E E K+L+ +DE I++ L S+LR+
Sbjct: 1386 KRQQQ---KDFIDGNVESLMTELEIEKSLKHHEDIVDEIE----CIEKTLLKRRSELREA 1438
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+A+ + +L + V+ D R +Q E+ A +L + V +
Sbjct: 1439 DRLLAEAESEL---SCTKEKTKNAVEKFTDAKRSL-LQTESDAEELERRAQETAVNLVKA 1494
Query: 347 IQQRDSLQAEVLECKQ---QIEKLTVQHKSAIQQLEED---LKQTKRALQEQCEITKREI 400
QQ SLQA+ + +Q + E++ + + + D L + K L E+ + +++I
Sbjct: 1495 DQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDI 1554
Query: 401 ELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E+ ER E LQ + + LQAK ELEK K + L +L KE L + +
Sbjct: 1555 EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ 1614
Query: 460 DEVTTCKREKESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI--- 514
+ K + + ++G + + + + ++ ++ Q EL N++++E+K
Sbjct: 1615 GSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGEL--NVQISERKTQLTL 1672
Query: 515 ---QYEQYVRDLQAHNRTIANCQ-ESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEI 569
+ E+ +LQ R ++ + E N + L+ E+ LK++ V E+
Sbjct: 1673 IKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVA 1732
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ----------QDL 619
+ ++ ELE + S+ Q I+ +++L+ K + + E ALQ +DL
Sbjct: 1733 VLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDL 1792
Query: 620 EHRMRIVDEV---NKQIAAKADE--------IQELFATLENKQQQIHRLEKIVLALXXXX 668
+ + I ++ K++ A A+E +++L + QQ++ +L + L+L
Sbjct: 1793 QEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDI 1852
Query: 669 XXXXXXXXXXXXKIAALEHELA 690
+ +L+ ELA
Sbjct: 1853 SAMQQQLQEKREAVNSLQEELA 1874
Score = 54.8 bits (126), Expect = 1e-06
Identities = 66/286 (23%), Positives = 129/286 (45%), Gaps = 27/286 (9%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
AKL+ + N++ ++++ ++ N +R E R +L K KL T E +
Sbjct: 773 AKLKHLQDDNNLLKQQLKDFQNHL-NHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHS 831
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+ + K L + + + + K D+++ +E +L+ +E L TG+ Q
Sbjct: 832 PSD---VLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQ 888
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
++ LE + +K QH++ IQQ+E ++ LQE + + E++
Sbjct: 889 ACER-------ALEARMNFDKR--QHEARIQQMENEIHY----LQENLKSME---EIQGL 932
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTED---- 460
T+ +LQ++ E + A++ ELEK K D ++ ++ L EL+ K+ + ++
Sbjct: 933 TDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATA 992
Query: 461 EVTTCKREKES--ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
E+T K + +S + I Q+ A EL E K R+L +
Sbjct: 993 ELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTR 1038
Score = 49.6 bits (113), Expect = 4e-05
Identities = 104/496 (20%), Positives = 215/496 (43%), Gaps = 47/496 (9%)
Query: 194 EDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENT 252
++ + T+ + +A +E R L E L++ + ++ Q+ + ++ + +R E +E
Sbjct: 622 QEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELE 681
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
AL+E +HE++ + + L+ E++L N QL+E +T LT
Sbjct: 682 SALQE-QHEVN---ASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLT---- 733
Query: 313 MLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHK 372
LE + Q E++ E +A L+ +L + + + Q+ L A++ + L Q K
Sbjct: 734 QLEQSALQAELEKERQA--LKNALGKAQFSEEKE-QENSELHAKLKHLQDDNNLLKQQLK 790
Query: 373 SAIQQLEEDLKQTKRALQEQCEITKREIELKERT-ETELQDSRN----AIEELQAKIIE- 426
L + R + + + +LK T E + + ++ +LQ + E
Sbjct: 791 DFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEI 850
Query: 427 LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT-TCKREKES-------ENKIGIQ 478
L +SK D RE L E+ +E L ++E C+R E+ +++ IQ
Sbjct: 851 LARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQ 910
Query: 479 QK------LAAELLNKEEIIG--KMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
Q L L + EEI G +Q+Q + K L + + ++ ++ + D ++ +
Sbjct: 911 QMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVF 970
Query: 531 A---NCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
++ ++ D E+ K +L + ++++ A++ QE E+ + +
Sbjct: 971 GLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAA 1030
Query: 586 GQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
AR + E I +L+N Q E L+ + + + N Q+ EI++L
Sbjct: 1031 QAARDLTRAEAEIELLQNL-LRQKGEQFRLEME---KTGVGTGANSQVL----EIEKLNE 1082
Query: 646 TLENKQQQIHRLEKIV 661
T+E ++ +I RL+ ++
Sbjct: 1083 TMERQRTEIARLQNVL 1098
Score = 46.8 bits (106), Expect = 3e-04
Identities = 81/421 (19%), Positives = 178/421 (42%), Gaps = 33/421 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT----ESQLRQTRNRVAKMDK 295
+E ++L + K E + L ++ + +L + KL E Q+ + + +A K
Sbjct: 472 EEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQK 531
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
++++ + +I SL + + + Q + ++L K + S+L + +
Sbjct: 532 EIKDLQIAIDSLDSK----DPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAK 587
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE--------------QCEITKREIE 401
E E K E+LT +A + L++DL+ LQE +C + E E
Sbjct: 588 ETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKE 647
Query: 402 LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDE 461
+ TE++ R+ +E + + K + + + ++ A LQ T+ L E E
Sbjct: 648 TLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAE 707
Query: 462 VTTCKREKESE-NKIGIQQKLAAELLNKEEIIGKMQIQ-TRELIKNIKLNEQKVIQYEQY 519
+ +++E N++ + + L E+ + +++ R+ +KN Q + EQ
Sbjct: 708 LEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQE 767
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
+L A + + Q+ N L+Q++ D + L VV E+ A+ D EL +
Sbjct: 768 NSELHA---KLKHLQDDNN-----LLKQQLKDFQNHLNHVVDGLVRPEEVAARVD-ELRR 818
Query: 580 QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ K G+ + + L L + + + S LA + + + ++ +++A + ++
Sbjct: 819 KLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEK 878
Query: 640 I 640
+
Sbjct: 879 L 879
Score = 41.5 bits (93), Expect = 0.010
Identities = 64/363 (17%), Positives = 161/363 (44%), Gaps = 19/363 (5%)
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL---E 359
S+ SL G +D+ E +L L+ + T +L ++ E+ +
Sbjct: 246 SLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDK 305
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRAL-QEQCEITK---REIELKERTETELQDSR- 414
+ +++ + K + ++L+ DL L Q+ E+T+ ++ EL++ D++
Sbjct: 306 LNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQELAFYKIDAKF 365
Query: 415 NAIEELQAKIIELEKSKP-NPDLPTER-EIDLWA-ELQATKETLRVTEDEVTTCKREKES 471
+ ++ E++K+ +P + R + +++A E V ++ ++ +
Sbjct: 366 EPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRND 425
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ L +L +KE+ I Q + EL I+ EQ++++ + + L+ + +
Sbjct: 426 HMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQ-LK 484
Query: 532 NCQESPNGISYQDLQ---QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQA 588
E+ + Y+ L Q + L+ + LD+ + E+ + +A K +E+ K+ +
Sbjct: 485 KISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEI----KDLQIAI 540
Query: 589 RVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
+ ++ + +K +++ + ++L + + + +DE+ +IA + +EI++L L
Sbjct: 541 DSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLT 600
Query: 649 NKQ 651
Q
Sbjct: 601 EGQ 603
Score = 39.1 bits (87), Expect = 0.052
Identities = 48/256 (18%), Positives = 118/256 (46%), Gaps = 19/256 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVM-- 238
+L E + E A+ + KR HE R + + E+ L++++++ +
Sbjct: 878 KLATGQEEFRQACERALEARMNFDKRQ-HEARI-----QQMENEIHYLQENLKSMEEIQG 931
Query: 239 IDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--- 295
+ +++ ++ E + L ++R +++ +E++ + +L++ + VA DK
Sbjct: 932 LTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLAT 991
Query: 296 -QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
+L A+ + SL GTV + + ++ + E +RK ++ + +++ ++ L+
Sbjct: 992 AELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLR 1051
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLE-EDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ + + ++EK V + Q LE E L +T +++ EI + L+ + D+
Sbjct: 1052 QKGEQFRLEMEKTGVGTGANSQVLEIEKLNETME--RQRTEIAR----LQNVLDLTGSDN 1105
Query: 414 RNAIEELQAKIIELEK 429
+ E + +I EL +
Sbjct: 1106 KGGFENVLEEIAELRR 1121
Score = 35.5 bits (78), Expect = 0.64
Identities = 71/373 (19%), Positives = 148/373 (39%), Gaps = 30/373 (8%)
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
L++ E Q + +D +A +++E+L + + + EE + R L+E
Sbjct: 244 LRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQ 303
Query: 396 TKREIELKERTETELQ-------DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
K LKE + Q D E L+ K IEL ++ E+E+ + ++
Sbjct: 304 DKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRA-CQKQYELEQELAFY-KI 361
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
A E L E + + IG + + + E I I + + ++ K+
Sbjct: 362 DAKFEPLNYYPSEYAEIDKAPDESPYIG-KSRYKRNMFATESYI----IDSAQAVQIKKM 416
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS-----YQDLQQEIMDLKMKLLDVVHRN 563
+ ++ + +L+ H ++ IS +L EI + ++L
Sbjct: 417 EPDEQLRNDH--MNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEF 474
Query: 564 EELSEILAKKDQELEQQD---KNSRGQARVI-KIREELINVLKNKETEQSRELAALQQDL 619
++L E + K +D K G+ +++ K+R+E ++ L+ + +Q +E+A Q+++
Sbjct: 475 KQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALD-LELQMEKQKQEIAGKQKEI 533
Query: 620 EHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXX 679
+ +D ++ +K + + A K+QQ+ + K L
Sbjct: 534 KDLQIAIDSLD----SKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKET 589
Query: 680 XKIAALEHELAAG 692
+I LE +L G
Sbjct: 590 EEIKDLEEQLTEG 602
>AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein.
Length = 1793
Score = 75.8 bits (178), Expect = 5e-13
Identities = 115/516 (22%), Positives = 235/516 (45%), Gaps = 44/516 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE---- 241
L +LK+Q + L ++ H++ L + ++V+ A L++ + + E
Sbjct: 1050 LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNH 1109
Query: 242 IRELRSESENTKALE-EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
IRE++S E + E+ ++ E +T IK+++ E L+ +++K +L+
Sbjct: 1110 IREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNI 1169
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTT-SQLIQQRDSLQAEVL 358
+ ++ L+ Q Q+ +LE + L E L+ + SQ + Q ++L
Sbjct: 1170 LDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLL 1229
Query: 359 EC-KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-------TKREIELKERT---- 406
E K++IE++T + + A+Q E L + K LQE+C+I TKR + E
Sbjct: 1230 ERDKREIERMTAESR-ALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKME 1288
Query: 407 ETELQDSRNAIEELQAKIIELEKSK---------PNPDLPTEREI--DLWAELQATKETL 455
++ L+ + +LQ ++ +L + K L +RE L EL ++ L
Sbjct: 1289 QSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHL 1348
Query: 456 RVT-EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGK----MQIQTRELIKNIKLNE 510
+ +D + T K + ++ QK +E N+ E K Q Q + L I+ N+
Sbjct: 1349 NLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENK 1408
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEI 569
K++Q E + LQ + +ES S L+++ L+ +L D + ++ LS++
Sbjct: 1409 LKLVQQEMMFQRLQKERES----EESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 1464
Query: 570 LAKKD--QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
LA ++ + L+++++ + + + ++ + + E+S EL ALQ++ +
Sbjct: 1465 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 1524
Query: 628 EVNKQIAAKADEIQELFATL-ENKQQQIHRLEKIVL 662
+ Q + + ++ A+L E + Q +LEK +L
Sbjct: 1525 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLL 1560
Score = 75.4 bits (177), Expect = 6e-13
Identities = 121/562 (21%), Positives = 244/562 (43%), Gaps = 55/562 (9%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
DI++HL + + + R+ + + E+ + + DL + E+++L E L R V
Sbjct: 798 DIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQ----EKKSLECEVEELHRTVQ 853
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
K +Q ++ + + L +E E K+L+ +DE I++ L S+LR+
Sbjct: 854 KRQQQ---KDFIDGNVESLMTELEIEKSLKHHEDIVDEIE----CIEKTLLKRRSELREA 906
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+A+ + +L + V+ D R +Q E+ A +L + V +
Sbjct: 907 DRLLAEAESEL---SCTKEKTKNAVEKFTDAKRSL-LQTESDAEELERRAQETAVNLVKA 962
Query: 347 IQQRDSLQAEVLECKQ---QIEKLTVQHKSAIQQLEED---LKQTKRALQEQCEITKREI 400
QQ SLQA+ + +Q + E++ + + + D L + K L E+ + +++I
Sbjct: 963 DQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDI 1022
Query: 401 ELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E+ ER E LQ + + LQAK ELEK K + L +L KE L + +
Sbjct: 1023 EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ 1082
Query: 460 DEVTTCKREKESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI--- 514
+ K + + ++G + + + + ++ ++ Q EL N++++E+K
Sbjct: 1083 GSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGEL--NVQISERKTQLTL 1140
Query: 515 ---QYEQYVRDLQAHNRTIANCQ-ESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEI 569
+ E+ +LQ R ++ + E N + L+ E+ LK++ V E+
Sbjct: 1141 IKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVA 1200
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ----------QDL 619
+ ++ ELE + S+ Q I+ +++L+ K + + E ALQ +DL
Sbjct: 1201 VLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDL 1260
Query: 620 EHRMRIVDEV---NKQIAAKADE--------IQELFATLENKQQQIHRLEKIVLALXXXX 668
+ + I ++ K++ A A+E +++L + QQ++ +L + L+L
Sbjct: 1261 QEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDI 1320
Query: 669 XXXXXXXXXXXXKIAALEHELA 690
+ +L+ ELA
Sbjct: 1321 SAMQQQLQEKREAVNSLQEELA 1342
Score = 54.8 bits (126), Expect = 1e-06
Identities = 66/286 (23%), Positives = 129/286 (45%), Gaps = 27/286 (9%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
AKL+ + N++ ++++ ++ N +R E R +L K KL T E +
Sbjct: 247 AKLKHLQDDNNLLKQQLKDFQNHL-NHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHS 305
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+ + K L + + + + K D+++ +E +L+ +E L TG+ Q
Sbjct: 306 PSD---VLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQ 362
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
++ LE + +K QH++ IQQ+E ++ LQE + + E++
Sbjct: 363 ACER-------ALEARMNFDKR--QHEARIQQMENEIHY----LQENLKSME---EIQGL 406
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTED---- 460
T+ +LQ++ E + A++ ELEK K D ++ ++ L EL+ K+ + ++
Sbjct: 407 TDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATA 466
Query: 461 EVTTCKREKES--ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
E+T K + +S + I Q+ A EL E K R+L +
Sbjct: 467 ELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTR 512
Score = 49.6 bits (113), Expect = 4e-05
Identities = 104/496 (20%), Positives = 215/496 (43%), Gaps = 47/496 (9%)
Query: 194 EDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENT 252
++ + T+ + +A +E R L E L++ + ++ Q+ + ++ + +R E +E
Sbjct: 96 QEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELE 155
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
AL+E +HE++ + + L+ E++L N QL+E +T LT
Sbjct: 156 SALQE-QHEVN---ASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLT---- 207
Query: 313 MLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHK 372
LE + Q E++ E +A L+ +L + + + Q+ L A++ + L Q K
Sbjct: 208 QLEQSALQAELEKERQA--LKNALGKAQF-SEEKEQENSELHAKLKHLQDDNNLLKQQLK 264
Query: 373 SAIQQLEEDLKQTKRALQEQCEITKREIELKERT-ETELQDSRN----AIEELQAKIIE- 426
L + R + + + +LK T E + + ++ +LQ + E
Sbjct: 265 DFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEI 324
Query: 427 LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEV-TTCKREKES-------ENKIGIQ 478
L +SK D RE L E+ +E L ++E C+R E+ +++ IQ
Sbjct: 325 LARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQ 384
Query: 479 QK------LAAELLNKEEIIG--KMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
Q L L + EEI G +Q+Q + K L + + ++ ++ + D ++ +
Sbjct: 385 QMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVF 444
Query: 531 A---NCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
++ ++ D E+ K +L + ++++ A++ QE E+ + +
Sbjct: 445 GLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAA 504
Query: 586 GQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
AR + E I +L+N Q E L+ + + + N Q+ EI++L
Sbjct: 505 QAARDLTRAEAEIELLQNL-LRQKGEQFRLEME---KTGVGTGANSQVL----EIEKLNE 556
Query: 646 TLENKQQQIHRLEKIV 661
T+E ++ +I RL+ ++
Sbjct: 557 TMERQRTEIARLQNVL 572
Score = 39.9 bits (89), Expect = 0.030
Identities = 65/335 (19%), Positives = 143/335 (42%), Gaps = 15/335 (4%)
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
+G + L+ ++Q + QLE+R L E L T ++ + L + + ++K
Sbjct: 32 SGKEQQLDIMNKQYQ-QLESR---LDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKD 87
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
S +Q+ +K Q +C + E E + TE++ R+ +E + +
Sbjct: 88 LEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENM 147
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE-NKIGIQQKLAAELL 486
K + + + ++ A LQ T+ L E E+ +++E N++ + + L
Sbjct: 148 RKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLT 207
Query: 487 NKEEIIGKMQIQ-TRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDL 545
E+ + +++ R+ +KN Q + EQ +L A + + Q+ N L
Sbjct: 208 QLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHA---KLKHLQDDNN-----LL 259
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
+Q++ D + L VV E+ A+ D EL ++ K G+ + + L L + +
Sbjct: 260 KQQLKDFQNHLNHVVDGLVRPEEVAARVD-ELRRKLKLGTGEMNIHSPSDVLGKSLADLQ 318
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI 640
+ S LA + + + ++ +++A + +++
Sbjct: 319 KQFSEILARSKWERDEAQVRERKLQEEMALQQEKL 353
>AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein.
Length = 2325
Score = 75.8 bits (178), Expect = 5e-13
Identities = 115/516 (22%), Positives = 235/516 (45%), Gaps = 44/516 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE---- 241
L +LK+Q + L ++ H++ L + ++V+ A L++ + + E
Sbjct: 1582 LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNH 1641
Query: 242 IRELRSESENTKALE-EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
IRE++S E + E+ ++ E +T IK+++ E L+ +++K +L+
Sbjct: 1642 IREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNI 1701
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTT-SQLIQQRDSLQAEVL 358
+ ++ L+ Q Q+ +LE + L E L+ + SQ + Q ++L
Sbjct: 1702 LDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLL 1761
Query: 359 EC-KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-------TKREIELKERT---- 406
E K++IE++T + + A+Q E L + K LQE+C+I TKR + E
Sbjct: 1762 ERDKREIERMTAESR-ALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKME 1820
Query: 407 ETELQDSRNAIEELQAKIIELEKSK---------PNPDLPTEREI--DLWAELQATKETL 455
++ L+ + +LQ ++ +L + K L +RE L EL ++ L
Sbjct: 1821 QSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHL 1880
Query: 456 RVT-EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGK----MQIQTRELIKNIKLNE 510
+ +D + T K + ++ QK +E N+ E K Q Q + L I+ N+
Sbjct: 1881 NLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENK 1940
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEI 569
K++Q E + LQ + +ES S L+++ L+ +L D + ++ LS++
Sbjct: 1941 LKLVQQEMMFQRLQKERES----EESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 1996
Query: 570 LAKKD--QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
LA ++ + L+++++ + + + ++ + + E+S EL ALQ++ +
Sbjct: 1997 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 2056
Query: 628 EVNKQIAAKADEIQELFATL-ENKQQQIHRLEKIVL 662
+ Q + + ++ A+L E + Q +LEK +L
Sbjct: 2057 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLL 2092
Score = 75.4 bits (177), Expect = 6e-13
Identities = 121/562 (21%), Positives = 244/562 (43%), Gaps = 55/562 (9%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
DI++HL + + + R+ + + E+ + + DL + E+++L E L R V
Sbjct: 1330 DIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQ----EKKSLECEVEELHRTVQ 1385
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
K +Q ++ + + L +E E K+L+ +DE I++ L S+LR+
Sbjct: 1386 KRQQQ---KDFIDGNVESLMTELEIEKSLKHHEDIVDEIE----CIEKTLLKRRSELREA 1438
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+A+ + +L + V+ D R +Q E+ A +L + V +
Sbjct: 1439 DRLLAEAESEL---SCTKEKTKNAVEKFTDAKRSL-LQTESDAEELERRAQETAVNLVKA 1494
Query: 347 IQQRDSLQAEVLECKQ---QIEKLTVQHKSAIQQLEED---LKQTKRALQEQCEITKREI 400
QQ SLQA+ + +Q + E++ + + + D L + K L E+ + +++I
Sbjct: 1495 DQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDI 1554
Query: 401 ELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
E+ ER E LQ + + LQAK ELEK K + L +L KE L + +
Sbjct: 1555 EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ 1614
Query: 460 DEVTTCKREKESENKIGIQQ--KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI--- 514
+ K + + ++G + + + + ++ ++ Q EL N++++E+K
Sbjct: 1615 GSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGEL--NVQISERKTQLTL 1672
Query: 515 ---QYEQYVRDLQAHNRTIANCQ-ESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEELSEI 569
+ E+ +LQ R ++ + E N + L+ E+ LK++ V E+
Sbjct: 1673 IKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVA 1732
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ----------QDL 619
+ ++ ELE + S+ Q I+ +++L+ K + + E ALQ +DL
Sbjct: 1733 VLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDL 1792
Query: 620 EHRMRIVDEV---NKQIAAKADE--------IQELFATLENKQQQIHRLEKIVLALXXXX 668
+ + I ++ K++ A A+E +++L + QQ++ +L + L+L
Sbjct: 1793 QEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDI 1852
Query: 669 XXXXXXXXXXXXKIAALEHELA 690
+ +L+ ELA
Sbjct: 1853 SAMQQQLQEKREAVNSLQEELA 1874
Score = 54.8 bits (126), Expect = 1e-06
Identities = 66/286 (23%), Positives = 129/286 (45%), Gaps = 27/286 (9%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
AKL+ + N++ ++++ ++ N +R E R +L K KL T E +
Sbjct: 773 AKLKHLQDDNNLLKQQLKDFQNHL-NHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHS 831
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+ + K L + + + + K D+++ +E +L+ +E L TG+ Q
Sbjct: 832 PSD---VLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQ 888
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
++ LE + +K QH++ IQQ+E ++ LQE + + E++
Sbjct: 889 ACER-------ALEARMNFDKR--QHEARIQQMENEIHY----LQENLKSME---EIQGL 932
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTED---- 460
T+ +LQ++ E + A++ ELEK K D ++ ++ L EL+ K+ + ++
Sbjct: 933 TDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATA 992
Query: 461 EVTTCKREKES--ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
E+T K + +S + I Q+ A EL E K R+L +
Sbjct: 993 ELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTR 1038
Score = 49.6 bits (113), Expect = 4e-05
Identities = 104/496 (20%), Positives = 215/496 (43%), Gaps = 47/496 (9%)
Query: 194 EDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENT 252
++ + T+ + +A +E R L E L++ + ++ Q+ + ++ + +R E +E
Sbjct: 622 QEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELE 681
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
AL+E +HE++ + + L+ E++L N QL+E +T LT
Sbjct: 682 SALQE-QHEVN---ASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLT---- 733
Query: 313 MLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHK 372
LE + Q E++ E +A L+ +L + + + Q+ L A++ + L Q K
Sbjct: 734 QLEQSALQAELEKERQA--LKNALGKAQFSEEKE-QENSELHAKLKHLQDDNNLLKQQLK 790
Query: 373 SAIQQLEEDLKQTKRALQEQCEITKREIELKERT-ETELQDSRN----AIEELQAKIIE- 426
L + R + + + +LK T E + + ++ +LQ + E
Sbjct: 791 DFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEI 850
Query: 427 LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT-TCKREKES-------ENKIGIQ 478
L +SK D RE L E+ +E L ++E C+R E+ +++ IQ
Sbjct: 851 LARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQ 910
Query: 479 QK------LAAELLNKEEIIG--KMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
Q L L + EEI G +Q+Q + K L + + ++ ++ + D ++ +
Sbjct: 911 QMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVF 970
Query: 531 A---NCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
++ ++ D E+ K +L + ++++ A++ QE E+ + +
Sbjct: 971 GLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAA 1030
Query: 586 GQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
AR + E I +L+N Q E L+ + + + N Q+ EI++L
Sbjct: 1031 QAARDLTRAEAEIELLQNL-LRQKGEQFRLEME---KTGVGTGANSQVL----EIEKLNE 1082
Query: 646 TLENKQQQIHRLEKIV 661
T+E ++ +I RL+ ++
Sbjct: 1083 TMERQRTEIARLQNVL 1098
Score = 46.8 bits (106), Expect = 3e-04
Identities = 81/421 (19%), Positives = 178/421 (42%), Gaps = 33/421 (7%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT----ESQLRQTRNRVAKMDK 295
+E ++L + K E + L ++ + +L + KL E Q+ + + +A K
Sbjct: 472 EEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQK 531
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
++++ + +I SL + + + Q + ++L K + S+L + +
Sbjct: 532 EIKDLQIAIDSLDSK----DPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAK 587
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE--------------QCEITKREIE 401
E E K E+LT +A + L++DL+ LQE +C + E E
Sbjct: 588 ETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKE 647
Query: 402 LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDE 461
+ TE++ R+ +E + + K + + + ++ A LQ T+ L E E
Sbjct: 648 TLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAE 707
Query: 462 VTTCKREKESE-NKIGIQQKLAAELLNKEEIIGKMQIQ-TRELIKNIKLNEQKVIQYEQY 519
+ +++E N++ + + L E+ + +++ R+ +KN Q + EQ
Sbjct: 708 LEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQE 767
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
+L A + + Q+ N L+Q++ D + L VV E+ A+ D EL +
Sbjct: 768 NSELHA---KLKHLQDDNN-----LLKQQLKDFQNHLNHVVDGLVRPEEVAARVD-ELRR 818
Query: 580 QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ K G+ + + L L + + + S LA + + + ++ +++A + ++
Sbjct: 819 KLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEK 878
Query: 640 I 640
+
Sbjct: 879 L 879
Score = 41.5 bits (93), Expect = 0.010
Identities = 64/363 (17%), Positives = 161/363 (44%), Gaps = 19/363 (5%)
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL---E 359
S+ SL G +D+ E +L L+ + T +L ++ E+ +
Sbjct: 246 SLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDK 305
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRAL-QEQCEITK---REIELKERTETELQDSR- 414
+ +++ + K + ++L+ DL L Q+ E+T+ ++ EL++ D++
Sbjct: 306 LNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQELAFYKIDAKF 365
Query: 415 NAIEELQAKIIELEKSKP-NPDLPTER-EIDLWA-ELQATKETLRVTEDEVTTCKREKES 471
+ ++ E++K+ +P + R + +++A E V ++ ++ +
Sbjct: 366 EPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRND 425
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ L +L +KE+ I Q + EL I+ EQ++++ + + L+ + +
Sbjct: 426 HMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQ-LK 484
Query: 532 NCQESPNGISYQDLQ---QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQA 588
E+ + Y+ L Q + L+ + LD+ + E+ + +A K +E+ K+ +
Sbjct: 485 KISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEI----KDLQIAI 540
Query: 589 RVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
+ ++ + +K +++ + ++L + + + +DE+ +IA + +EI++L L
Sbjct: 541 DSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLT 600
Query: 649 NKQ 651
Q
Sbjct: 601 EGQ 603
Score = 39.1 bits (87), Expect = 0.052
Identities = 48/256 (18%), Positives = 118/256 (46%), Gaps = 19/256 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVM-- 238
+L E + E A+ + KR HE R + + E+ L++++++ +
Sbjct: 878 KLATGQEEFRQACERALEARMNFDKRQ-HEARI-----QQMENEIHYLQENLKSMEEIQG 931
Query: 239 IDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--- 295
+ +++ ++ E + L ++R +++ +E++ + +L++ + VA DK
Sbjct: 932 LTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLAT 991
Query: 296 -QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
+L A+ + SL GTV + + ++ + E +RK ++ + +++ ++ L+
Sbjct: 992 AELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLR 1051
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLE-EDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ + + ++EK V + Q LE E L +T +++ EI + L+ + D+
Sbjct: 1052 QKGEQFRLEMEKTGVGTGANSQVLEIEKLNETME--RQRTEIAR----LQNVLDLTGSDN 1105
Query: 414 RNAIEELQAKIIELEK 429
+ E + +I EL +
Sbjct: 1106 KGGFENVLEEIAELRR 1121
Score = 35.5 bits (78), Expect = 0.64
Identities = 71/373 (19%), Positives = 148/373 (39%), Gaps = 30/373 (8%)
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
L++ E Q + +D +A +++E+L + + + EE + R L+E
Sbjct: 244 LRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQ 303
Query: 396 TKREIELKERTETELQ-------DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
K LKE + Q D E L+ K IEL ++ E+E+ + ++
Sbjct: 304 DKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRA-CQKQYELEQELAFY-KI 361
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
A E L E + + IG + + + E I I + + ++ K+
Sbjct: 362 DAKFEPLNYYPSEYAEIDKAPDESPYIG-KSRYKRNMFATESYI----IDSAQAVQIKKM 416
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS-----YQDLQQEIMDLKMKLLDVVHRN 563
+ ++ + +L+ H ++ IS +L EI + ++L
Sbjct: 417 EPDEQLRNDH--MNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEF 474
Query: 564 EELSEILAKKDQELEQQD---KNSRGQARVI-KIREELINVLKNKETEQSRELAALQQDL 619
++L E + K +D K G+ +++ K+R+E ++ L+ + +Q +E+A Q+++
Sbjct: 475 KQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALD-LELQMEKQKQEIAGKQKEI 533
Query: 620 EHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXX 679
+ +D ++ +K + + A K+QQ+ + K L
Sbjct: 534 KDLQIAIDSLD----SKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKET 589
Query: 680 XKIAALEHELAAG 692
+I LE +L G
Sbjct: 590 EEIKDLEEQLTEG 602
>BC027860-1|AAH27860.1| 893|Homo sapiens filamin A interacting
protein 1-like protein.
Length = 893
Score = 75.4 bits (177), Expect = 6e-13
Identities = 103/470 (21%), Positives = 213/470 (45%), Gaps = 34/470 (7%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
++E+ ++ T+ + + E R E + T+ +E++ + + + I KLT +S
Sbjct: 20 IQELTTNAKETHTK-LALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDS 78
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED------QSRQKEVQLEARARKLRES 335
Q RQ + ++A + +Q+ E E + SL + L+D + + A +LR+
Sbjct: 79 QNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKR 138
Query: 336 LKTGEVTTSQLI----QQRD---SLQAEVLECKQ---QIEKLTVQHKSAIQQLEEDLKQT 385
+ E +LI Q RD L+ E L+ K ++EKL+ + A+++LE+ ++
Sbjct: 139 VLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLS-KRIMALEKLEDAFNKS 197
Query: 386 KRALQE-QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK--PNPDLPTEREI 442
K+ +C + K + K+ ++ EL+ + I+EL+A LEK++ DL + +
Sbjct: 198 KQECYSLKCNLEKERMTTKQLSQ-ELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTL 256
Query: 443 DLW--AELQATKETLRVTEDEVTTCKREKESE-NKI-GIQQKLAAE----LLNKEEIIGK 494
+ E + E L+ TED++ + + E NK+ + +KL E L +K ++ K
Sbjct: 257 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 316
Query: 495 MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
M T+E ++K K+ E+ DL + + N +S I L+ ++
Sbjct: 317 MYSVTKER-DDLK---NKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSG 372
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
K +H+ + L+++ + L+ + K+ + + E+ L+ + + +
Sbjct: 373 KSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQF 432
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
L ++LEH + + + Q LF L+ ++ + L + V AL
Sbjct: 433 LSKELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDAL 482
Score = 53.2 bits (122), Expect = 3e-06
Identities = 80/423 (18%), Positives = 184/423 (43%), Gaps = 26/423 (6%)
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
T L R ++ E T KL E+++++ + +++K+L+ T+
Sbjct: 10 TAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTI 69
Query: 312 --KMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTV 369
K+ + S+ + QL+ + L + E T L + + LQ + K++I K
Sbjct: 70 MAKLTNEDSQNR--QLQQKLAALSRQIDELEETNRSLRKAEEELQ----DIKEKISKGEY 123
Query: 370 QHKSAIQQLEEDLKQTKRALQEQCEITKRE---IELKERTETELQDSRN---AIEELQAK 423
+ + ++EE K+ + E+ K E +L +R E E S++ +E+L +
Sbjct: 124 GNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKR 183
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK-REKESENKIGIQQKLA 482
I+ LEK + + + L L+ + T + E+ + K R KE E I+ +L
Sbjct: 184 IMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE---AIESRLE 240
Query: 483 AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVR----DLQAHNRTIANCQESPN 538
+E + K++ T + K +K+ + E ++ LQ + E
Sbjct: 241 KTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLI 300
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEEL-SEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ + L+ + D++ K+ V ++L +++ A++++ + + + + R+ +
Sbjct: 301 EETKRALKSK-TDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIE 359
Query: 598 INVLKNKETEQS-RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ LKNK + S + AL Q+ ++++ + + +++ K +++ + L + +
Sbjct: 360 KDFLKNKLNQDSGKSTTALHQE-NNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYET 418
Query: 657 LEK 659
LE+
Sbjct: 419 LER 421
>AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protein
130d protein.
Length = 1135
Score = 75.4 bits (177), Expect = 6e-13
Identities = 103/470 (21%), Positives = 213/470 (45%), Gaps = 34/470 (7%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
++E+ ++ T+ + + E R E + T+ +E++ + + + I KLT +S
Sbjct: 260 IQELTTNAKETHTK-LALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDS 318
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED------QSRQKEVQLEARARKLRES 335
Q RQ + ++A + +Q+ E E + SL + L+D + + A +LR+
Sbjct: 319 QNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKR 378
Query: 336 LKTGEVTTSQLI----QQRD---SLQAEVLECKQ---QIEKLTVQHKSAIQQLEEDLKQT 385
+ E +LI Q RD L+ E L+ K ++EKL+ + A+++LE+ ++
Sbjct: 379 VLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLS-KRIMALEKLEDAFNKS 437
Query: 386 KRALQE-QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK--PNPDLPTEREI 442
K+ +C + K + K+ ++ EL+ + I+EL+A LEK++ DL + +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQ-ELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTL 496
Query: 443 DLW--AELQATKETLRVTEDEVTTCKREKESE-NKI-GIQQKLAAE----LLNKEEIIGK 494
+ E + E L+ TED++ + + E NK+ + +KL E L +K ++ K
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 495 MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
M T+E ++K K+ E+ DL + + N +S I L+ ++
Sbjct: 557 MYSVTKER-DDLK---NKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSG 612
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
K +H+ + L+++ + L+ + K+ + + E+ L+ + + +
Sbjct: 613 KSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQF 672
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
L ++LEH + + + Q LF L+ ++ + L + V AL
Sbjct: 673 LSKELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDAL 722
Score = 67.3 bits (157), Expect = 2e-10
Identities = 93/465 (20%), Positives = 196/465 (42%), Gaps = 34/465 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
EAL R+ + + ++ + EL E K E R L + A+ + ++ +
Sbjct: 117 EALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHK--ESYRRILGQLLVAEKSHRQTILE 174
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT 338
E + R+ + + K D+ + E L + +KE + E R L+E L
Sbjct: 175 LEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTK 234
Query: 339 GEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
+ ++ ++ L A++ +Q+I++LT K +L L + R +E+ + T+
Sbjct: 235 LKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLA--LAEA-RVQEEEQKATRL 291
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
E EL+ +T QD + +L + + + R+ID EL+ T +LR
Sbjct: 292 EKELQTQTTKFHQDQDTIMAKLTNEDSQ-NRQLQQKLAALSRQID---ELEETNRSLRKA 347
Query: 459 EDEVTTCKRE--KESENKIGIQ------QKLAAELLNKEEIIGKMQIQTREL-------- 502
E+E+ K + K GI +K ++ K+E + KM+ Q R+L
Sbjct: 348 EEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERET 407
Query: 503 --IKNIKLNEQKVIQYEQYVRDLQ-AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV 559
K+ KL +K+ + + L+ A N++ C + + + + + +++ L V
Sbjct: 408 LQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKV 467
Query: 560 VHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDL 619
+ E E +K + ++D V+ + E K K+TE + A+ Q +
Sbjct: 468 RIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQV 527
Query: 620 EHRM------RIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
E ++++E + + +K D +++++ + + ++L+
Sbjct: 528 EQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Score = 44.0 bits (99), Expect = 0.002
Identities = 72/356 (20%), Positives = 149/356 (41%), Gaps = 34/356 (9%)
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK-----------LTV---QHKSAI 375
+K+ E+L+ Q D + + E + +EK L V H+ I
Sbjct: 113 KKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSHRQTI 172
Query: 376 QQLEEDLKQTKRALQEQCE---ITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSK 431
+LEE+ ++ K +++ E + ++E E LK+ + E++ +E + ++ L++
Sbjct: 173 LELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEEL 232
Query: 432 PNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEI 491
+D L A R E+TT KE+ K+ + + E K
Sbjct: 233 TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTT--NAKETHTKLALAEARVQEEEQKATR 290
Query: 492 IGK-MQIQTRELIKNIKLNEQKVIQYEQYVRDLQ----AHNRTIANCQESPNGISYQDLQ 546
+ K +Q QT + ++ K+ + R LQ A +R I +E+ S + +
Sbjct: 291 LEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNR--SLRKAE 348
Query: 547 QEIMDLKMKLLDVVHRNEE-LSEILAKKDQELEQQDKNSRGQARVIKIREEL--INVLKN 603
+E+ D+K K+ + N ++E+ + + L+ + K+ +IK+ E+ +N
Sbjct: 349 EELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDE----ELIKMEEQCRDLNKRLE 404
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ET QS++ + L R+ ++++ E L LE ++ +L +
Sbjct: 405 RETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQ 460
>AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protein
130c protein.
Length = 1133
Score = 75.4 bits (177), Expect = 6e-13
Identities = 103/470 (21%), Positives = 213/470 (45%), Gaps = 34/470 (7%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
++E+ ++ T+ + + E R E + T+ +E++ + + + I KLT +S
Sbjct: 260 IQELTTNAKETHTK-LALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDS 318
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED------QSRQKEVQLEARARKLRES 335
Q RQ + ++A + +Q+ E E + SL + L+D + + A +LR+
Sbjct: 319 QNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKR 378
Query: 336 LKTGEVTTSQLI----QQRD---SLQAEVLECKQ---QIEKLTVQHKSAIQQLEEDLKQT 385
+ E +LI Q RD L+ E L+ K ++EKL+ + A+++LE+ ++
Sbjct: 379 VLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLS-KRIMALEKLEDAFNKS 437
Query: 386 KRALQE-QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK--PNPDLPTEREI 442
K+ +C + K + K+ ++ EL+ + I+EL+A LEK++ DL + +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQ-ELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTL 496
Query: 443 DLW--AELQATKETLRVTEDEVTTCKREKESE-NKI-GIQQKLAAE----LLNKEEIIGK 494
+ E + E L+ TED++ + + E NK+ + +KL E L +K ++ K
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 495 MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
M T+E ++K K+ E+ DL + + N +S I L+ ++
Sbjct: 557 MYSVTKER-DDLK---NKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSG 612
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
K +H+ + L+++ + L+ + K+ + + E+ L+ + + +
Sbjct: 613 KSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQF 672
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
L ++LEH + + + Q LF L+ ++ + L + V AL
Sbjct: 673 LSKELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDAL 722
Score = 67.3 bits (157), Expect = 2e-10
Identities = 93/465 (20%), Positives = 196/465 (42%), Gaps = 34/465 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
EAL R+ + + ++ + EL E K E R L + A+ + ++ +
Sbjct: 117 EALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHK--ESYRRILGQLLVAEKSRRQTILE 174
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT 338
E + R+ + + K D+ + E L + +KE + E R L+E L
Sbjct: 175 LEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTK 234
Query: 339 GEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
+ ++ ++ L A++ +Q+I++LT K +L L + R +E+ + T+
Sbjct: 235 LKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLA--LAEA-RVQEEEQKATRL 291
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
E EL+ +T QD + +L + + + R+ID EL+ T +LR
Sbjct: 292 EKELQTQTTKFHQDQDTIMAKLTNEDSQ-NRQLQQKLAALSRQID---ELEETNRSLRKA 347
Query: 459 EDEVTTCKRE--KESENKIGIQ------QKLAAELLNKEEIIGKMQIQTREL-------- 502
E+E+ K + K GI +K ++ K+E + KM+ Q R+L
Sbjct: 348 EEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERET 407
Query: 503 --IKNIKLNEQKVIQYEQYVRDLQ-AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV 559
K+ KL +K+ + + L+ A N++ C + + + + + +++ L V
Sbjct: 408 LQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKV 467
Query: 560 VHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDL 619
+ E E +K + ++D V+ + E K K+TE + A+ Q +
Sbjct: 468 RIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQV 527
Query: 620 EHRM------RIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
E ++++E + + +K D +++++ + + ++L+
Sbjct: 528 EQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Score = 43.2 bits (97), Expect = 0.003
Identities = 73/356 (20%), Positives = 149/356 (41%), Gaps = 34/356 (9%)
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK-----------LTVQHKS---AI 375
+K+ E+L+ Q D + + E + +EK L V KS I
Sbjct: 113 KKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTI 172
Query: 376 QQLEEDLKQTKRALQEQCE---ITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSK 431
+LEE+ ++ K +++ E + ++E E LK+ + E++ +E + ++ L++
Sbjct: 173 LELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEEL 232
Query: 432 PNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEI 491
+D L A R E+TT KE+ K+ + + E K
Sbjct: 233 TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTT--NAKETHTKLALAEARVQEEEQKATR 290
Query: 492 IGK-MQIQTRELIKNIKLNEQKVIQYEQYVRDLQ----AHNRTIANCQESPNGISYQDLQ 546
+ K +Q QT + ++ K+ + R LQ A +R I +E+ S + +
Sbjct: 291 LEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNR--SLRKAE 348
Query: 547 QEIMDLKMKLLDVVHRNEE-LSEILAKKDQELEQQDKNSRGQARVIKIREEL--INVLKN 603
+E+ D+K K+ + N ++E+ + + L+ + K+ +IK+ E+ +N
Sbjct: 349 EELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDE----ELIKMEEQCRDLNKRLE 404
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ET QS++ + L R+ ++++ E L LE ++ +L +
Sbjct: 405 RETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQ 460
>AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protein
130b protein.
Length = 1133
Score = 75.4 bits (177), Expect = 6e-13
Identities = 103/470 (21%), Positives = 213/470 (45%), Gaps = 34/470 (7%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
++E+ ++ T+ + + E R E + T+ +E++ + + + I KLT +S
Sbjct: 260 IQELTTNAKETHTK-LALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDS 318
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED------QSRQKEVQLEARARKLRES 335
Q RQ + ++A + +Q+ E E + SL + L+D + + A +LR+
Sbjct: 319 QNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKR 378
Query: 336 LKTGEVTTSQLI----QQRD---SLQAEVLECKQ---QIEKLTVQHKSAIQQLEEDLKQT 385
+ E +LI Q RD L+ E L+ K ++EKL+ + A+++LE+ ++
Sbjct: 379 VLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLS-KRIMALEKLEDAFNKS 437
Query: 386 KRALQE-QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK--PNPDLPTEREI 442
K+ +C + K + K+ ++ EL+ + I+EL+A LEK++ DL + +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQ-ELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTL 496
Query: 443 DLW--AELQATKETLRVTEDEVTTCKREKESE-NKI-GIQQKLAAE----LLNKEEIIGK 494
+ E + E L+ TED++ + + E NK+ + +KL E L +K ++ K
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 495 MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
M T+E ++K K+ E+ DL + + N +S I L+ ++
Sbjct: 557 MYSVTKER-DDLK---NKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSG 612
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
K +H+ + L+++ + L+ + K+ + + E+ L+ + + +
Sbjct: 613 KSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQF 672
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
L ++LEH + + + Q LF L+ ++ + L + V AL
Sbjct: 673 LSKELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDAL 722
Score = 67.3 bits (157), Expect = 2e-10
Identities = 93/465 (20%), Positives = 196/465 (42%), Gaps = 34/465 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
EAL R+ + + ++ + EL E K E R L + A+ + ++ +
Sbjct: 117 EALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHK--ESYRRILGQLLVAEKSHRQTILE 174
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT 338
E + R+ + + K D+ + E L + +KE + E R L+E L
Sbjct: 175 LEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTK 234
Query: 339 GEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
+ ++ ++ L A++ +Q+I++LT K +L L + R +E+ + T+
Sbjct: 235 LKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLA--LAEA-RVQEEEQKATRL 291
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
E EL+ +T QD + +L + + + R+ID EL+ T +LR
Sbjct: 292 EKELQTQTTKFHQDQDTIMAKLTNEDSQ-NRQLQQKLAALSRQID---ELEETNRSLRKA 347
Query: 459 EDEVTTCKRE--KESENKIGIQ------QKLAAELLNKEEIIGKMQIQTREL-------- 502
E+E+ K + K GI +K ++ K+E + KM+ Q R+L
Sbjct: 348 EEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERET 407
Query: 503 --IKNIKLNEQKVIQYEQYVRDLQ-AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV 559
K+ KL +K+ + + L+ A N++ C + + + + + +++ L V
Sbjct: 408 LQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKV 467
Query: 560 VHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDL 619
+ E E +K + ++D V+ + E K K+TE + A+ Q +
Sbjct: 468 RIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQV 527
Query: 620 EHRM------RIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
E ++++E + + +K D +++++ + + ++L+
Sbjct: 528 EQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Score = 44.0 bits (99), Expect = 0.002
Identities = 72/356 (20%), Positives = 149/356 (41%), Gaps = 34/356 (9%)
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK-----------LTV---QHKSAI 375
+K+ E+L+ Q D + + E + +EK L V H+ I
Sbjct: 113 KKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSHRQTI 172
Query: 376 QQLEEDLKQTKRALQEQCE---ITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSK 431
+LEE+ ++ K +++ E + ++E E LK+ + E++ +E + ++ L++
Sbjct: 173 LELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEEL 232
Query: 432 PNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEI 491
+D L A R E+TT KE+ K+ + + E K
Sbjct: 233 TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTT--NAKETHTKLALAEARVQEEEQKATR 290
Query: 492 IGK-MQIQTRELIKNIKLNEQKVIQYEQYVRDLQ----AHNRTIANCQESPNGISYQDLQ 546
+ K +Q QT + ++ K+ + R LQ A +R I +E+ S + +
Sbjct: 291 LEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNR--SLRKAE 348
Query: 547 QEIMDLKMKLLDVVHRNEE-LSEILAKKDQELEQQDKNSRGQARVIKIREEL--INVLKN 603
+E+ D+K K+ + N ++E+ + + L+ + K+ +IK+ E+ +N
Sbjct: 349 EELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDE----ELIKMEEQCRDLNKRLE 404
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ET QS++ + L R+ ++++ E L LE ++ +L +
Sbjct: 405 RETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQ 460
>AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protein
130a protein.
Length = 1135
Score = 75.4 bits (177), Expect = 6e-13
Identities = 103/470 (21%), Positives = 213/470 (45%), Gaps = 34/470 (7%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
++E+ ++ T+ + + E R E + T+ +E++ + + + I KLT +S
Sbjct: 260 IQELTTNAKETHTK-LALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDS 318
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED------QSRQKEVQLEARARKLRES 335
Q RQ + ++A + +Q+ E E + SL + L+D + + A +LR+
Sbjct: 319 QNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKR 378
Query: 336 LKTGEVTTSQLI----QQRD---SLQAEVLECKQ---QIEKLTVQHKSAIQQLEEDLKQT 385
+ E +LI Q RD L+ E L+ K ++EKL+ + A+++LE+ ++
Sbjct: 379 VLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLS-KRIMALEKLEDAFNKS 437
Query: 386 KRALQE-QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK--PNPDLPTEREI 442
K+ +C + K + K+ ++ EL+ + I+EL+A LEK++ DL + +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQ-ELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTL 496
Query: 443 DLW--AELQATKETLRVTEDEVTTCKREKESE-NKI-GIQQKLAAE----LLNKEEIIGK 494
+ E + E L+ TED++ + + E NK+ + +KL E L +K ++ K
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 495 MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
M T+E ++K K+ E+ DL + + N +S I L+ ++
Sbjct: 557 MYSVTKER-DDLK---NKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSG 612
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
K +H+ + L+++ + L+ + K+ + + E+ L+ + + +
Sbjct: 613 KSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQF 672
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
L ++LEH + + + Q LF L+ ++ + L + V AL
Sbjct: 673 LSKELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDAL 722
Score = 67.3 bits (157), Expect = 2e-10
Identities = 93/465 (20%), Positives = 196/465 (42%), Gaps = 34/465 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
EAL R+ + + ++ + EL E K E R L + A+ + ++ +
Sbjct: 117 EALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHK--ESYRRILGQLLVAEKSRRQTILE 174
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT 338
E + R+ + + K D+ + E L + +KE + E R L+E L
Sbjct: 175 LEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTK 234
Query: 339 GEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
+ ++ ++ L A++ +Q+I++LT K +L L + R +E+ + T+
Sbjct: 235 LKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLA--LAEA-RVQEEEQKATRL 291
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
E EL+ +T QD + +L + + + R+ID EL+ T +LR
Sbjct: 292 EKELQTQTTKFHQDQDTIMAKLTNEDSQ-NRQLQQKLAALSRQID---ELEETNRSLRKA 347
Query: 459 EDEVTTCKRE--KESENKIGIQ------QKLAAELLNKEEIIGKMQIQTREL-------- 502
E+E+ K + K GI +K ++ K+E + KM+ Q R+L
Sbjct: 348 EEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERET 407
Query: 503 --IKNIKLNEQKVIQYEQYVRDLQ-AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV 559
K+ KL +K+ + + L+ A N++ C + + + + + +++ L V
Sbjct: 408 LQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKV 467
Query: 560 VHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDL 619
+ E E +K + ++D V+ + E K K+TE + A+ Q +
Sbjct: 468 RIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQV 527
Query: 620 EHRM------RIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
E ++++E + + +K D +++++ + + ++L+
Sbjct: 528 EQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Score = 43.2 bits (97), Expect = 0.003
Identities = 73/356 (20%), Positives = 149/356 (41%), Gaps = 34/356 (9%)
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK-----------LTVQHKS---AI 375
+K+ E+L+ Q D + + E + +EK L V KS I
Sbjct: 113 KKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTI 172
Query: 376 QQLEEDLKQTKRALQEQCE---ITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSK 431
+LEE+ ++ K +++ E + ++E E LK+ + E++ +E + ++ L++
Sbjct: 173 LELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEEL 232
Query: 432 PNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEI 491
+D L A R E+TT KE+ K+ + + E K
Sbjct: 233 TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTT--NAKETHTKLALAEARVQEEEQKATR 290
Query: 492 IGK-MQIQTRELIKNIKLNEQKVIQYEQYVRDLQ----AHNRTIANCQESPNGISYQDLQ 546
+ K +Q QT + ++ K+ + R LQ A +R I +E+ S + +
Sbjct: 291 LEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNR--SLRKAE 348
Query: 547 QEIMDLKMKLLDVVHRNEE-LSEILAKKDQELEQQDKNSRGQARVIKIREEL--INVLKN 603
+E+ D+K K+ + N ++E+ + + L+ + K+ +IK+ E+ +N
Sbjct: 349 EELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDE----ELIKMEEQCRDLNKRLE 404
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ET QS++ + L R+ ++++ E L LE ++ +L +
Sbjct: 405 RETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQ 460
>AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protein
90 protein.
Length = 764
Score = 75.4 bits (177), Expect = 6e-13
Identities = 103/470 (21%), Positives = 213/470 (45%), Gaps = 34/470 (7%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
++E+ ++ T+ + + E R E + T+ +E++ + + + I KLT +S
Sbjct: 260 IQELTTNAKETHTK-LALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDS 318
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED------QSRQKEVQLEARARKLRES 335
Q RQ + ++A + +Q+ E E + SL + L+D + + A +LR+
Sbjct: 319 QNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKR 378
Query: 336 LKTGEVTTSQLI----QQRD---SLQAEVLECKQ---QIEKLTVQHKSAIQQLEEDLKQT 385
+ E +LI Q RD L+ E L+ K ++EKL+ + A+++LE+ ++
Sbjct: 379 VLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLS-KRIMALEKLEDAFNKS 437
Query: 386 KRALQE-QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK--PNPDLPTEREI 442
K+ +C + K + K+ ++ EL+ + I+EL+A LEK++ DL + +
Sbjct: 438 KQECYSLKCNLEKERMTTKQLSQ-ELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTL 496
Query: 443 DLW--AELQATKETLRVTEDEVTTCKREKESE-NKI-GIQQKLAAE----LLNKEEIIGK 494
+ E + E L+ TED++ + + E NK+ + +KL E L +K ++ K
Sbjct: 497 TVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEK 556
Query: 495 MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
M T+E ++K K+ E+ DL + + N +S I L+ ++
Sbjct: 557 MYSVTKER-DDLK---NKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSG 612
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
K +H+ + L+++ + L+ + K+ + + E+ L+ + + +
Sbjct: 613 KSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQF 672
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
L ++LEH + + + Q LF L+ ++ + L + V AL
Sbjct: 673 LSKELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDAL 722
Score = 67.3 bits (157), Expect = 2e-10
Identities = 93/465 (20%), Positives = 196/465 (42%), Gaps = 34/465 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
EAL R+ + + ++ + EL E K E R L + A+ + ++ +
Sbjct: 117 EALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHK--ESYRRILGQLLVAEKSRRQTILE 174
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT 338
E + R+ + + K D+ + E L + +KE + E R L+E L
Sbjct: 175 LEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTK 234
Query: 339 GEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
+ ++ ++ L A++ +Q+I++LT K +L L + R +E+ + T+
Sbjct: 235 LKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLA--LAEA-RVQEEEQKATRL 291
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
E EL+ +T QD + +L + + + R+ID EL+ T +LR
Sbjct: 292 EKELQTQTTKFHQDQDTIMAKLTNEDSQ-NRQLQQKLAALSRQID---ELEETNRSLRKA 347
Query: 459 EDEVTTCKRE--KESENKIGIQ------QKLAAELLNKEEIIGKMQIQTREL-------- 502
E+E+ K + K GI +K ++ K+E + KM+ Q R+L
Sbjct: 348 EEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERET 407
Query: 503 --IKNIKLNEQKVIQYEQYVRDLQ-AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV 559
K+ KL +K+ + + L+ A N++ C + + + + + +++ L V
Sbjct: 408 LQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKV 467
Query: 560 VHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDL 619
+ E E +K + ++D V+ + E K K+TE + A+ Q +
Sbjct: 468 RIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQV 527
Query: 620 EHRM------RIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
E ++++E + + +K D +++++ + + ++L+
Sbjct: 528 EQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Score = 43.2 bits (97), Expect = 0.003
Identities = 73/356 (20%), Positives = 149/356 (41%), Gaps = 34/356 (9%)
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK-----------LTVQHKS---AI 375
+K+ E+L+ Q D + + E + +EK L V KS I
Sbjct: 113 KKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTI 172
Query: 376 QQLEEDLKQTKRALQEQCE---ITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSK 431
+LEE+ ++ K +++ E + ++E E LK+ + E++ +E + ++ L++
Sbjct: 173 LELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEEL 232
Query: 432 PNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEI 491
+D L A R E+TT KE+ K+ + + E K
Sbjct: 233 TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTT--NAKETHTKLALAEARVQEEEQKATR 290
Query: 492 IGK-MQIQTRELIKNIKLNEQKVIQYEQYVRDLQ----AHNRTIANCQESPNGISYQDLQ 546
+ K +Q QT + ++ K+ + R LQ A +R I +E+ S + +
Sbjct: 291 LEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNR--SLRKAE 348
Query: 547 QEIMDLKMKLLDVVHRNEE-LSEILAKKDQELEQQDKNSRGQARVIKIREEL--INVLKN 603
+E+ D+K K+ + N ++E+ + + L+ + K+ +IK+ E+ +N
Sbjct: 349 EELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDE----ELIKMEEQCRDLNKRLE 404
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ET QS++ + L R+ ++++ E L LE ++ +L +
Sbjct: 405 RETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQ 460
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 75.4 bits (177), Expect = 6e-13
Identities = 99/470 (21%), Positives = 205/470 (43%), Gaps = 28/470 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 907 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 966
Query: 241 EIRELRSESEN-TKALEEMRHELDEE----RTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++ + + +EN K L E LDE K A++E T L+ ++V + K
Sbjct: 967 KVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTK 1026
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
+ E + L G++ +Q ++ + LE RKL LK + +T + L
Sbjct: 1027 AKTKLEQQVDDLEGSL----EQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNE 1082
Query: 356 EVLECKQQIEKL--TVQHKSAI-QQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
++ + + ++ L ++ + A+ QL++ +K+ + ++E E + E + + E + D
Sbjct: 1083 KLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142
Query: 413 SRNAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKE-TLRVTEDEVTTCKREKE 470
+EE+ ++ E + +L +RE + + +E TL+ K+ +
Sbjct: 1143 LSRELEEISERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHAD 1202
Query: 471 SENKIGIQQKLAAELLNK-EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRT 529
S ++G Q + K E+ +++++ +L N++ + +E+ R L+
Sbjct: 1203 SVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSE 1262
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQAR 589
I +E + Q+ I +L + + + E S L +KD + Q SRG+
Sbjct: 1263 IKTKEE--------EQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQL---SRGKQA 1311
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKAD 638
+ EEL L+ +ET+ LA Q H ++ ++ ++ AKA+
Sbjct: 1312 FTQQIEELKRQLE-EETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAE 1360
Score = 68.1 bits (159), Expect = 1e-10
Identities = 90/441 (20%), Positives = 196/441 (44%), Gaps = 40/441 (9%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E E+T KE+L TE++ ++ ++ + ++ +
Sbjct: 839 KIKPLLKSAETEKEMANMKEEF--EKT-----KEELAKTEAKRKELEEKMVTLMQEKNDL 891
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 892 QLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDEC 951
Query: 358 LECKQQIEKLTV------QHKSAIQQLEEDLKQTKRALQEQ-CEITKREIELKERTETEL 410
E K+ I+ L + + K A + ++L + L E ++TK + L+E + L
Sbjct: 952 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1011
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
D ++ + K+ L K+K E+++D +L+ + E + ++ KR+ E
Sbjct: 1012 DD----LQMEEDKVNTLTKAKTK----LEQQVD---DLEGSLEQEKKLCMDLERAKRKLE 1060
Query: 471 SENKIGIQQKLAAELLNKE--EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNR 528
+ K+ + + E ++ E + K + + L I+ + +Q ++ +++LQA
Sbjct: 1061 GDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIE 1120
Query: 529 TIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-----SEILAKKDQELEQQDKN 583
+ E+ S +++ DL +L ++ R EE ++I K +E E Q K
Sbjct: 1121 ELEEEIEAERA-SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIELNKKREAEFQ-KM 1178
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
R E L+ K + +A L + ++ R+ ++ K+ + EI +L
Sbjct: 1179 RRDLEESTLQHEATAAALRKKHAD---SVAELGKQIDSLQRVKQKLEKEKSELKMEINDL 1235
Query: 644 FATLENKQQQIHRLEKIVLAL 664
+ +E + EK+ L
Sbjct: 1236 ASNMETVSKAKANFEKMCRTL 1256
Score = 64.5 bits (150), Expect = 1e-09
Identities = 98/469 (20%), Positives = 189/469 (40%), Gaps = 34/469 (7%)
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
R L + K EE + L E +A+ K +L T + + + M QL +
Sbjct: 1254 RTLEDQLSEIKTKEEEQQRLINELSAQ---KARLHTESGEFSRQLDEKDAMVSQLSRGKQ 1310
Query: 303 SITSLTGTVK-MLEDQSRQKEVQLEA--RARK----LRESLKTGEVTTSQLIQQRDSLQA 355
+ T +K LE++++ K A AR LRE + + ++L + +
Sbjct: 1311 AFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANS 1370
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI----ELKERTETELQ 411
EV + + + E +Q +++ ++ L Q + +E E + + K+R + E++
Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVE 1430
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTT--CKREK 469
D +E A I L+K + N D + E QA E + ++T K +
Sbjct: 1431 DLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKN 1490
Query: 470 ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRT 529
E + + L E N ++ I + Q E K+I E+ Q + +LQ
Sbjct: 1491 AYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQT---- 1546
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQAR 589
+ +E+ + +++ +I+ ++++L V E+ +A+KD+EL+Q +N R
Sbjct: 1547 --SLEEAEASLEHEE--GKILRIQLELNQV---KSEIDRKIAEKDEELDQLKRN---HLR 1596
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
V++ + ++ + R ++ DL ++ N+Q A ++ L
Sbjct: 1597 VVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGIL-- 1654
Query: 650 KQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
K Q+H L+ + A +E EL A L R ER
Sbjct: 1655 KDTQLH-LDDAIRGQDDLKEQLAMVERRANLMQAEVE-ELRASLERTER 1701
Score = 54.8 bits (126), Expect = 1e-06
Identities = 94/470 (20%), Positives = 208/470 (44%), Gaps = 48/470 (10%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
E K+R+D+E + + E ++ ++ E+ ++D + +K+KL +S+L
Sbjct: 1174 EFQKMRRDLE-ESTLQHEATAAALRKKHADSVAELGKQIDSLQR----VKQKLEKEKSEL 1228
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVK--MLEDQSRQKEVQL---EARARKLRESLKT 338
+ N +A + + +A+A+ + T++ + E +++++E Q E A+K R ++
Sbjct: 1229 KMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTES 1288
Query: 339 GEVT---------TSQLIQQRDSLQAEVLECKQQIEKLTVQHKS---AIQQLEEDLKQTK 386
GE + SQL + + + ++ E K+Q+E+ T + A+Q D +
Sbjct: 1289 GEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLR 1348
Query: 387 RALQEQCE--------ITKREIELKE-RTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
+E+ E ++K E+ + RT+ E D+ EEL+ +L + + +
Sbjct: 1349 EQYEEEQEAKAELQRGMSKANSEVAQWRTKYE-TDAIQRTEELEEAKKKLAQRLQDAEEH 1407
Query: 438 TEREIDLWAELQATKETLR-VTEDEVTTCKREKES----ENKIGIQQKLAAELLNK-EEI 491
E A L+ TK+ L+ ED + +R + + K K+ AE K EE
Sbjct: 1408 VEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEET 1467
Query: 492 IGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQDLQ--QE 548
+++ +E +++ KV YE+ + L+ R N Q+ + ++ Q + +
Sbjct: 1468 QAELEASQKE-SRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKH 1526
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQ 608
I +L+ + H EL L + + LE + + ++++I+ EL V + +
Sbjct: 1527 IHELEKVKKQLDHEKSELQTSLEEAEASLEHE------EGKILRIQLELNQVKSEIDRKI 1580
Query: 609 SRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ + L Q + +R+V+ + + A+ + + + ++ +E
Sbjct: 1581 AEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEME 1630
Score = 45.2 bits (102), Expect = 8e-04
Identities = 59/258 (22%), Positives = 111/258 (43%), Gaps = 19/258 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV-ETRNVMI 239
EL +L + + A + D S+R + L +L+ KL D+ + + M
Sbjct: 1691 ELRASLERTERGRKMAEQELLDASERV----QLLHTQNTSLINTKKKLETDISQIQGEME 1746
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
D ++E R+ E K + D A+ KE+ T+ + + D QLR
Sbjct: 1747 DIVQEARNAEEKAK-----KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1801
Query: 300 AEASITSLTG---TVKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSL 353
EA +L G ++ LE + R+ E ++E+ + E++K E +L Q +
Sbjct: 1802 GEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEED 1861
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER---TETEL 410
+ +L + ++KL + K+ +Q EE +Q+ L + ++ E +ER E+++
Sbjct: 1862 RKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQV 1921
Query: 411 QDSRNAIEELQAKIIELE 428
R E+ K+I E
Sbjct: 1922 NKLRVKSREVHTKVISEE 1939
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain
(1437 AA) protein.
Length = 1437
Score = 74.9 bits (176), Expect = 9e-13
Identities = 98/480 (20%), Positives = 206/480 (42%), Gaps = 18/480 (3%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 405 ERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 464
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQ--L 297
++ + + +EN K L E LD E AKL+ KEK E+ + + A+ DK L
Sbjct: 465 KVEKEKHATENKVKNLTEEMAGLD-ETIAKLS-KEKKALQETHQQTLDDLQAEEDKVNIL 522
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + +T + L ++
Sbjct: 523 TKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKL 582
Query: 358 LECKQQIEKL--TVQHKSAIQ-QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ + +I L ++ + A++ QL++ +K+ + ++E E + E + + E + D
Sbjct: 583 EKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLS 642
Query: 415 NAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESEN 473
+EE+ ++ E + +L +RE + + +L+ E + + + R+K +++
Sbjct: 643 RELEEISERLEEAGGATSAQVELNKKREAE-FQKLRRDLEEATLQHEAMVAALRKKHADS 701
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
+L ++ N + + K++ + EL + +L+
Sbjct: 702 ----MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKDGGRSLED 757
Query: 534 QESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
Q S ++ Q+ I DL + + E S L +KD + Q ++ + + I
Sbjct: 758 QVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQI-- 815
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ 653
EEL + L+ +ET+ LA Q H ++ E ++ E+Q + ++ Q
Sbjct: 816 -EELKHQLE-EETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ 873
Score = 74.1 bits (174), Expect = 1e-12
Identities = 82/432 (18%), Positives = 191/432 (44%), Gaps = 32/432 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E + K++L +E++ ++ ++ + K+ +
Sbjct: 337 KIKPLLKSAETEKEMATMKEEFQKT-------KDELAKSEAKRKELEEKMVTLLKEKNDL 389
Query: 301 EASITSLTGTVKMLEDQSRQ---KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + S ++ E++ Q ++QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 390 QLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDEC 449
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + +
Sbjct: 450 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTL 509
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K E+++D +L+ + E + ++ KR+ E + K
Sbjct: 510 DDLQAEEDKVNILTKAKTK----LEQQVD---DLEGSLEQEKKLRMDLERAKRKLEGDLK 562
Query: 475 IGIQQKLAAE--LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
+ + + E +E + K + + LI I+ + IQ ++ +++LQA +
Sbjct: 563 LAQESTMDNENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGE 622
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-----SEILAKKDQELEQQDKNSRGQ 587
E+ S +++ DL +L ++ R EE +++ K +E E Q K R
Sbjct: 623 EIEAERA-SRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQ-KLRRDL 680
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATL 647
E ++ L+ K + +A L + +++ R+ ++ K+ + E +L +
Sbjct: 681 EEATLQHEAMVAALRKKHAD---SMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNA 737
Query: 648 ENKQQQIHRLEK 659
E + LEK
Sbjct: 738 EAISKAKGNLEK 749
Score = 70.1 bits (164), Expect = 2e-11
Identities = 93/514 (18%), Positives = 215/514 (41%), Gaps = 31/514 (6%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
++ E + EL R+L+ + + + DL + A +
Sbjct: 423 EVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 482
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERT---AKLAIKEKLTTTESQL 283
++ ET + E + L+ + T L++++ E D+ AK +++++ E L
Sbjct: 483 EMAGLDETIAKLSKEKKALQETHQQT--LDDLQAEEDKVNILTKAKTKLEQQVDDLEGSL 540
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARA---RKLRESLKTGE 340
Q + +++ R+ E + + E+ +Q + +LE + L ++ +
Sbjct: 541 EQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKKEFEISNLISKIEDEQ 600
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEITK 397
QL ++ LQA + E ++IE A +Q L +L++ L+E T
Sbjct: 601 AVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS 660
Query: 398 REIELKERTETELQDSRNAIEEL----QAKIIELEKSKPNPDLPTEREID----LWAELQ 449
++EL ++ E E Q R +EE +A + L K + +ID + +L+
Sbjct: 661 AQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLE 720
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
K L++ D++++ E S+ K +++ L ++ + + + + LI ++
Sbjct: 721 KEKSELKMETDDLSS-NAEAISKAKGNLEKDGGRSLEDQVSELKTKEEEQQRLINDLTAQ 779
Query: 510 EQKV-IQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMD---LKMKLLDVVHRN 563
++ + +Y R L + ++ S + Q +L+ ++ + K L + +
Sbjct: 780 RARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS 839
Query: 564 EELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET---EQSRELAALQQDLE 620
++L ++Q E+Q+ + Q + K E+ N ET +++ EL ++ L
Sbjct: 840 RHDCDLL--REQYEEEQEGKAELQRALSKANSEVAQWRTNTETDAIQRTEELEEAKKKLA 897
Query: 621 HRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R++ +E + + AK +++ L+N+ + +
Sbjct: 898 QRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDL 931
Score = 67.7 bits (158), Expect = 1e-10
Identities = 113/560 (20%), Positives = 218/560 (38%), Gaps = 33/560 (5%)
Query: 118 QEVAQLYRDAIA-SSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYN 176
+ +A+L ++ A T + L+ L NI+ KT L D +G + +
Sbjct: 489 ETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRM 548
Query: 177 DQGFELCGALRELKTQAEDAVNTVTD-------LSKRACHERRTLIAVGEALVREVAKLR 229
D +LK E ++ D L K+ + + + E+ +L+
Sbjct: 549 DLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKKEFEISNLISKIEDEQAVEI-QLQ 607
Query: 230 QDVETRNVMIDEI-RELRSESENTKALEEMRHELDEE-RTAKLAIKEKLTTTESQLRQTR 287
+ ++ I+E+ E+ +E + E+ R +L E ++E T +Q+ +
Sbjct: 608 KKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNK 667
Query: 288 NRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLI 347
R A+ K R+ E + V L + +L + L+ + E S+L
Sbjct: 668 KREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK 727
Query: 348 QQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTE 407
+ D L + + L K + LE+ + + K +EQ + + R +
Sbjct: 728 METDDLSSNAEAISKAKGNL---EKDGGRSLEDQVSELKTKEEEQQRLINDLTAQRARLQ 784
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKETLRVTEDEVTTC- 465
TE + ++E A + +L +SK E + L E +A + C
Sbjct: 785 TEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCD 844
Query: 466 ----KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVR 521
+ E+E E K +Q+ L+ N E + +T + + +L E K + Q ++
Sbjct: 845 LLREQYEEEQEGKAELQRALSKA--NSEVAQWRTNTETDAIQRTEELEEAKK-KLAQRLQ 901
Query: 522 DLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQ 580
+ + H + A C + Q LQ E+ DL +LDV R+ L KK + ++
Sbjct: 902 EAEEHVEAVNAKCASLEK--TKQRLQNEVEDL---MLDV-ERSNAACAALDKKQRNFDKV 955
Query: 581 DKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI 640
S + + + + EL + + S EL ++ E + ++ + ++ EI
Sbjct: 956 --LSEWKQKYEETQAEL-EASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI 1012
Query: 641 QELFATLENKQQQIHRLEKI 660
+L + +QIH LEKI
Sbjct: 1013 SDLTEQIAEGGKQIHELEKI 1032
Score = 66.1 bits (154), Expect = 4e-10
Identities = 104/534 (19%), Positives = 231/534 (43%), Gaps = 59/534 (11%)
Query: 138 ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYN-----DQGFELCGALRELKTQ 192
E +D ++ ++ K+ L + D + E +S+ D G L + ELKT+
Sbjct: 707 EQIDNLQRVKQKLEKEKSELKMETDDLSSNA-EAISKAKGNLEKDGGRSLEDQVSELKTK 765
Query: 193 AEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT 252
E+ + DL+ + L E + + ++ ++ ++ ++ RS+ +T
Sbjct: 766 EEEQQRLINDLTAQRAR-----------LQTEAGEYSRQLDEKDALVSQLS--RSKQAST 812
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
+ +EE++H+L+EE AK A+ L ++ R + + + E + +++ V
Sbjct: 813 QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 872
Query: 313 M----LEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
E + Q+ +LE +KL + L+ E + + SL+ + ++E L
Sbjct: 873 QWRTNTETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 932
Query: 369 V---QHKSAIQQLEEDLKQTKRALQE---QCEITKREIELKER----TETELQDSRNAIE 418
+ + +A L++ + + L E + E T+ E+E ++ TEL +N E
Sbjct: 933 LDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYE 992
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
E ++ L + N ++EI E Q + ++ E E + E+E
Sbjct: 993 ESLDQLETLRRENKN----LQQEISDLTE-QIAEGGKQIHELEKIKKQVEQEKCEIQAAL 1047
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
++ A L ++E I ++Q++ ++ + ++K+ + ++ + L+ ++ + +S
Sbjct: 1048 EEAEASLEHEEGKILRIQLELNQVKSEV---DRKIAEKDEEIDQLKRNHTRVVETMQSTL 1104
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
+ + + + +K K+ +L+E+ E++ N R A ++
Sbjct: 1105 DAEIRS-RNDALRVKKKM------EGDLNEM------EIQLNHAN-RLAAESLRNYRNTQ 1150
Query: 599 NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+LK + L Q+DL+ ++ IV+ + A EI+EL+ATLE ++
Sbjct: 1151 GILKETQLHLDDALRG-QEDLKEQLAIVERRANLLQA---EIEELWATLEQTER 1200
Score = 60.9 bits (141), Expect = 1e-08
Identities = 98/471 (20%), Positives = 198/471 (42%), Gaps = 57/471 (12%)
Query: 160 NQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGE 219
N Q D+ E ++ Q EL ++++ + + + + HE ++ +
Sbjct: 1007 NLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQL 1066
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE---RTAKLAIKEK- 275
L + +++ + + ++ ID+++ +T+ +E M+ LD E R L +K+K
Sbjct: 1067 ELNQVKSEVDRKIAEKDEEIDQLKR-----NHTRVVETMQSTLDAEIRSRNDALRVKKKM 1121
Query: 276 ---LTTTESQLRQTRNRVAKMDKQLREAEASITS----LTGTVKMLEDQSRQKEVQLEAR 328
L E QL A+ + R + + L ++ ED Q + +E R
Sbjct: 1122 EGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI-VERR 1180
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
A L+ ++ T Q + R + E+L+ ++++ L Q+ S I TK+
Sbjct: 1181 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN--------TKKK 1232
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
L+ +L+ E +Q+SRNA E+ + I + ++E D A L
Sbjct: 1233 LENDVS------QLQSEVEEVIQESRNAEEKAKKAITDAAMMAEE----LKKEQDTSAHL 1282
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
+ K+ L T K+ ++++ ++LA L ++ I K++ + REL ++
Sbjct: 1283 ERMKKNLEQT---------VKDLQHRLDEAEQLA--LKGGKKQIQKLEARVRELEGEVE- 1330
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANC-----QESPNGISYQDLQQEIMDLKMKLLDVVHRN 563
NEQK + + V+ L+ H R + ++ N + QDL ++
Sbjct: 1331 NEQK--RNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEA 1388
Query: 564 EELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
EE S K ++L+ + + + +A I E +N L+ K E +++A
Sbjct: 1389 EEQSNANLSKFRKLQHELEEAEERA---DIAESQVNKLRVKSREVHTKISA 1436
>U53445-1|AAA98972.1| 752|Homo sapiens DOC1 protein.
Length = 752
Score = 74.9 bits (176), Expect = 9e-13
Identities = 98/458 (21%), Positives = 211/458 (46%), Gaps = 24/458 (5%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
++E+ ++ T+ + + E R E + T+ +E++ + + + I KLT +S
Sbjct: 20 IQELTTNAKETHTK-LALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDS 78
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED---QSRQKEVQLEARARKLRESLKT 338
Q RQ + ++A + +Q+ E E + SL + L+D + + E ++ E +K
Sbjct: 79 QNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELIKM 138
Query: 339 GEVTTS-QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE-QCEIT 396
E +R++LQ++ + K ++EKL+ + A+++LE+ ++K+ +C +
Sbjct: 139 EEQCRDLNKRLERETLQSK--DFKLEVEKLS-KRIMALEKLEDAFNKSKQECYSLKCNLE 195
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSK--PNPDLPTEREIDLW--AELQATK 452
K + K+ ++ EL+ + I+EL+A LEK++ DL + + + E +
Sbjct: 196 KERMTTKQLSQ-ELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMS 254
Query: 453 ETLRVTEDEVTTCKREKESE-NKI-GIQQKLAAE----LLNKEEIIGKMQIQTRELIKNI 506
E L+ TED++ + + E NK+ + +KL E L +K ++ KM T+E ++
Sbjct: 255 EKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKER-DDL 313
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL 566
K K+ E+ DL + + N +S I L+ ++ K +H+
Sbjct: 314 K---NKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNK 370
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIV 626
+ L+++ + L+ + K+ + + E+ L+ + + + L ++LEH +
Sbjct: 371 IKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMEL 430
Query: 627 DEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
+ + Q LF L+ ++ + L + V AL
Sbjct: 431 AKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDAL 468
Score = 57.2 bits (132), Expect = 2e-07
Identities = 78/417 (18%), Positives = 183/417 (43%), Gaps = 28/417 (6%)
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
T L R ++ E T KL E+++++ + +++K+L+ T+
Sbjct: 10 TAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTI 69
Query: 312 --KMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTV 369
K+ + S+ + QL+ + L + E T L + + LQ + K++I K
Sbjct: 70 MAKLTNEDSQNR--QLQQKLAALSRQIDELEETNRSLRKAEEELQ----DIKEKISKGEY 123
Query: 370 QHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEK 429
+ + ++EE +K ++EQC + + ER + +D + +E+L +I+ LEK
Sbjct: 124 GNAGIMAEVEELIK-----MEEQCRDLNKRL---ERETLQSKDFKLEVEKLSKRIMALEK 175
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK-REKESENKIGIQQKLAAELLNK 488
+ + + L L+ + T + E+ + K R KE E I+ +L
Sbjct: 176 LEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE---AIESRLEKTEFTL 232
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVR----DLQAHNRTIANCQESPNGISYQD 544
+E + K++ T + K +K+ + E ++ LQ + E + +
Sbjct: 233 KEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRA 292
Query: 545 LQQEIMDLKMKLLDVVHRNEEL-SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN 603
L+ + D++ K+ V ++L +++ A++++ + + + + R+ + + LKN
Sbjct: 293 LKSK-TDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKN 351
Query: 604 KETEQS-RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
K + S + AL Q+ ++++ + + +++ K +++ + L + + LE+
Sbjct: 352 KLNQDSGKSTTALHQE-NNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLER 407
>BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein
protein.
Length = 898
Score = 74.9 bits (176), Expect = 9e-13
Identities = 109/423 (25%), Positives = 188/423 (44%), Gaps = 42/423 (9%)
Query: 186 LRELKTQAEDAVNTVTDLS--KRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEI 242
LR+ + E N + LS K H+ T L+RE+ KL++D+ + + +
Sbjct: 336 LRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWA 395
Query: 243 R-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ +L++E ++ K E + +L E T KLT + + Q R M K +E+E
Sbjct: 396 QNKLKAEMDSHK---ETKDKLKETTT-------KLTQAKEEADQIRKNCQDMIKTYQESE 445
Query: 302 ASITS-----LTGTVKMLEDQSRQKEVQLEARARKLRE------SLKTGEVTTSQLIQQR 350
++ L T LE Q ++K QLE K++E + K G L +
Sbjct: 446 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 505
Query: 351 DSLQAEVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERT 406
L+ E L + ++ K + + K+ IQ L + +K T LQEQ + K+EIE LKE
Sbjct: 506 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-TADQLQEQLQRGKQEIENLKE-- 562
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E++ + I +LQ I K + L TER A+LQ+ +L+ D+V+ +
Sbjct: 563 --EVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSE 620
Query: 467 REKESENKIGIQQKLAAE-LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA 525
+ +S+ + Q + E L KEE + K ++QT + + E K + + V +L+
Sbjct: 621 SQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQ--VEELKD 678
Query: 526 HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
T Q + S +DL +++ + K LD V E+ + + N+R
Sbjct: 679 ELVT----QRRKHASSIKDLTKQLQQARRK-LDQVESGSYDKEVSSMGSRSSSSGSLNAR 733
Query: 586 GQA 588
A
Sbjct: 734 SSA 736
Score = 63.3 bits (147), Expect = 3e-09
Identities = 99/433 (22%), Positives = 184/433 (42%), Gaps = 21/433 (4%)
Query: 242 IRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
I +++S S + LEE+ EL A+ + + E L V DK L++
Sbjct: 150 ISKIKSVSASEDLLEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCV--QDKYLQQEH 207
Query: 302 ASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
+ K E D +K+ L +K E+ K T QL + + L EV
Sbjct: 208 IIKKLIKENKKHQELFVDICSEKD-NLREELKKRTETEKQHMNTIKQLESRIEELNKEVK 266
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK----ERTETELQDSR 414
+ Q+ V K+A+QQL +++ Q ++CE ++E E R E E D R
Sbjct: 267 ASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLR 326
Query: 415 NAIEELQAKI----IELEKSKPNPDLPTEREIDLWAELQATK--ETLRVTEDEVTTCKRE 468
E L+ K+ ELEK+ N +E +L TK ET R+ E+ K +
Sbjct: 327 KEKETLEKKLRDANKELEKN-TNKIKQLSQEKGRLHQLYETKEGETTRLIR-EIDKLKED 384
Query: 469 KESE-NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
S K+ Q KL AE+ + +E K++ T +L + + +Q + ++ Q
Sbjct: 385 INSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQES 444
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+N ++ ++ +L++++ + K L++ H + E L + +E + + R
Sbjct: 445 EEIKSNELDAKLRVTKGELEKQMQE-KSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRT 503
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ + ++ +K E A Q+L +++ D++ +Q+ EI+ L
Sbjct: 504 KVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEE 563
Query: 647 LENKQQQIHRLEK 659
+E+ I+ L+K
Sbjct: 564 VESLNSLINDLQK 576
Score = 51.2 bits (117), Expect = 1e-05
Identities = 89/433 (20%), Positives = 195/433 (45%), Gaps = 52/433 (12%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQ----LRQTRNRVAKMDKQLREAEASIT 305
EN K E E+ + +K++ T TE Q ++Q +R+ +++K+++ + +
Sbjct: 215 ENKKHQELFVDICSEKDNLREELKKR-TETEKQHMNTIKQLESRIEELNKEVKASRDQLI 273
Query: 306 SLTGTVKMLEDQSRQKEVQ-LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
+ T K Q ++ Q +E +K E+ + E + ++ + E L+ +++
Sbjct: 274 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRG----EKESLDLRKEK 329
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL-QDSRNAIEELQAK 423
E L + + A ++LE++ + K+ QE+ + + E KE T L ++ E++ +
Sbjct: 330 ETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQL-YETKEGETTRLIREIDKLKEDINSH 388
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG---IQQK 480
+I+++ ++ + E+D E TK+ L+ T ++T K E + K I+
Sbjct: 389 VIKVKWAQNK----LKAEMDSHKE---TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTY 441
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI---------- 530
+E + E+ K+++ EL K ++ ++ + +++L+ RT
Sbjct: 442 QESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTL 501
Query: 531 ---ANCQESPNGISYQDLQQ--EIMDLK----MKLLDVVHRNEELSEILAKKDQELEQQD 581
C E + +L + EI++ + LLD V ++L E L + QE+E
Sbjct: 502 RTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 561
Query: 582 KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
+ ++ LIN L+ K+ E SR+ + + L R+ + N Q+ ++++ +Q
Sbjct: 562 EE-------VESLNSLINDLQ-KDIEGSRKRES--ELLLFTERLTSK-NAQLQSESNSLQ 610
Query: 642 ELFATLENKQQQI 654
F + + Q+
Sbjct: 611 SQFDKVSCSESQL 623
>BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 74.9 bits (176), Expect = 9e-13
Identities = 109/423 (25%), Positives = 188/423 (44%), Gaps = 42/423 (9%)
Query: 186 LRELKTQAEDAVNTVTDLS--KRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEI 242
LR+ + E N + LS K H+ T L+RE+ KL++D+ + + +
Sbjct: 336 LRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWA 395
Query: 243 R-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ +L++E ++ K E + +L E T KLT + + Q R M K +E+E
Sbjct: 396 QNKLKAEMDSHK---ETKDKLKETTT-------KLTQAKEEADQIRKNCQDMIKTYQESE 445
Query: 302 ASITS-----LTGTVKMLEDQSRQKEVQLEARARKLRE------SLKTGEVTTSQLIQQR 350
++ L T LE Q ++K QLE K++E + K G L +
Sbjct: 446 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 505
Query: 351 DSLQAEVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERT 406
L+ E L + ++ K + + K+ IQ L + +K T LQEQ + K+EIE LKE
Sbjct: 506 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-TADQLQEQLQRGKQEIENLKE-- 562
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E++ + I +LQ I K + L TER A+LQ+ +L+ D+V+ +
Sbjct: 563 --EVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSE 620
Query: 467 REKESENKIGIQQKLAAE-LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA 525
+ +S+ + Q + E L KEE + K ++QT + + E K + + V +L+
Sbjct: 621 SQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQ--VEELKD 678
Query: 526 HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
T Q + S +DL +++ + K LD V E+ + + N+R
Sbjct: 679 ELVT----QRRKHASSIKDLTKQLQQARRK-LDQVESGSYDKEVSSMGSRSSSSGSLNAR 733
Query: 586 GQA 588
A
Sbjct: 734 SSA 736
Score = 63.3 bits (147), Expect = 3e-09
Identities = 99/433 (22%), Positives = 184/433 (42%), Gaps = 21/433 (4%)
Query: 242 IRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
I +++S S + LEE+ EL A+ + + E L V DK L++
Sbjct: 150 ISKIKSVSASEDLLEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCV--QDKYLQQEH 207
Query: 302 ASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
+ K E D +K+ L +K E+ K T QL + + L EV
Sbjct: 208 IIKKLIKENKKHQELFVDICSEKD-NLREELKKRTETEKQHMNTIKQLESRIEELNKEVK 266
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK----ERTETELQDSR 414
+ Q+ V K+A+QQL +++ Q ++CE ++E E R E E D R
Sbjct: 267 ASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLR 326
Query: 415 NAIEELQAKI----IELEKSKPNPDLPTEREIDLWAELQATK--ETLRVTEDEVTTCKRE 468
E L+ K+ ELEK+ N +E +L TK ET R+ E+ K +
Sbjct: 327 KEKETLEKKLRDANKELEKN-TNKIKQLSQEKGRLHQLYETKEGETTRLIR-EIDKLKED 384
Query: 469 KESE-NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
S K+ Q KL AE+ + +E K++ T +L + + +Q + ++ Q
Sbjct: 385 INSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQES 444
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+N ++ ++ +L++++ + K L++ H + E L + +E + + R
Sbjct: 445 EEIKSNELDAKLRVTKGELEKQMQE-KSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRT 503
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ + ++ +K E A Q+L +++ D++ +Q+ EI+ L
Sbjct: 504 KVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEE 563
Query: 647 LENKQQQIHRLEK 659
+E+ I+ L+K
Sbjct: 564 VESLNSLINDLQK 576
Score = 51.2 bits (117), Expect = 1e-05
Identities = 89/433 (20%), Positives = 195/433 (45%), Gaps = 52/433 (12%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQ----LRQTRNRVAKMDKQLREAEASIT 305
EN K E E+ + +K++ T TE Q ++Q +R+ +++K+++ + +
Sbjct: 215 ENKKHQELFVDICSEKDNLREELKKR-TETEKQHMNTIKQLESRIEELNKEVKASRDQLI 273
Query: 306 SLTGTVKMLEDQSRQKEVQ-LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
+ T K Q ++ Q +E +K E+ + E + ++ + E L+ +++
Sbjct: 274 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRG----EKESLDLRKEK 329
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL-QDSRNAIEELQAK 423
E L + + A ++LE++ + K+ QE+ + + E KE T L ++ E++ +
Sbjct: 330 ETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQL-YETKEGETTRLIREIDKLKEDINSH 388
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG---IQQK 480
+I+++ ++ + E+D E TK+ L+ T ++T K E + K I+
Sbjct: 389 VIKVKWAQNK----LKAEMDSHKE---TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTY 441
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI---------- 530
+E + E+ K+++ EL K ++ ++ + +++L+ RT
Sbjct: 442 QESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTL 501
Query: 531 ---ANCQESPNGISYQDLQQ--EIMDLK----MKLLDVVHRNEELSEILAKKDQELEQQD 581
C E + +L + EI++ + LLD V ++L E L + QE+E
Sbjct: 502 RTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 561
Query: 582 KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
+ ++ LIN L+ K+ E SR+ + + L R+ + N Q+ ++++ +Q
Sbjct: 562 EE-------VESLNSLINDLQ-KDIEGSRKRES--ELLLFTERLTSK-NAQLQSESNSLQ 610
Query: 642 ELFATLENKQQQI 654
F + + Q+
Sbjct: 611 SQFDKVSCSESQL 623
>BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 74.9 bits (176), Expect = 9e-13
Identities = 109/423 (25%), Positives = 188/423 (44%), Gaps = 42/423 (9%)
Query: 186 LRELKTQAEDAVNTVTDLS--KRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEI 242
LR+ + E N + LS K H+ T L+RE+ KL++D+ + + +
Sbjct: 336 LRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWA 395
Query: 243 R-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ +L++E ++ K E + +L E T KLT + + Q R M K +E+E
Sbjct: 396 QNKLKAEMDSHK---ETKDKLKETTT-------KLTQAKEEADQIRKNCQDMIKTYQESE 445
Query: 302 ASITS-----LTGTVKMLEDQSRQKEVQLEARARKLRE------SLKTGEVTTSQLIQQR 350
++ L T LE Q ++K QLE K++E + K G L +
Sbjct: 446 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 505
Query: 351 DSLQAEVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERT 406
L+ E L + ++ K + + K+ IQ L + +K T LQEQ + K+EIE LKE
Sbjct: 506 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-TADQLQEQLQRGKQEIENLKE-- 562
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E++ + I +LQ I K + L TER A+LQ+ +L+ D+V+ +
Sbjct: 563 --EVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSE 620
Query: 467 REKESENKIGIQQKLAAE-LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA 525
+ +S+ + Q + E L KEE + K ++QT + + E K + + V +L+
Sbjct: 621 SQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQ--VEELKD 678
Query: 526 HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
T Q + S +DL +++ + K LD V E+ + + N+R
Sbjct: 679 ELVT----QRRKHASSIKDLTKQLQQARRK-LDQVESGSYDKEVSSMGSRSSSSGSLNAR 733
Query: 586 GQA 588
A
Sbjct: 734 SSA 736
Score = 61.7 bits (143), Expect = 9e-09
Identities = 98/433 (22%), Positives = 184/433 (42%), Gaps = 21/433 (4%)
Query: 242 IRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
I +++S S + LEE+ EL A+ + + E L V DK L++
Sbjct: 150 ISKIKSVSASEDLLEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCV--QDKYLQQEH 207
Query: 302 ASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
+ K E D +K+ L +K E+ K T QL + + L EV
Sbjct: 208 IIKKLIKENKKHQELFVDICSEKD-NLREELKKRTETEKQHMNTIKQLESRIEELNKEVK 266
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK----ERTETELQDSR 414
+ ++ V K+A+QQL +++ Q ++CE ++E E R E E D R
Sbjct: 267 ASRDKLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLR 326
Query: 415 NAIEELQAKI----IELEKSKPNPDLPTEREIDLWAELQATK--ETLRVTEDEVTTCKRE 468
E L+ K+ ELEK+ N +E +L TK ET R+ E+ K +
Sbjct: 327 KEKETLEKKLRDANKELEKN-TNKIKQLSQEKGRLHQLYETKEGETTRLIR-EIDKLKED 384
Query: 469 KESE-NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
S K+ Q KL AE+ + +E K++ T +L + + +Q + ++ Q
Sbjct: 385 INSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQES 444
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+N ++ ++ +L++++ + K L++ H + E L + +E + + R
Sbjct: 445 EEIKSNELDAKLRVTKGELEKQMQE-KSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRT 503
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ + ++ +K E A Q+L +++ D++ +Q+ EI+ L
Sbjct: 504 KVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEE 563
Query: 647 LENKQQQIHRLEK 659
+E+ I+ L+K
Sbjct: 564 VESLNSLINDLQK 576
Score = 51.2 bits (117), Expect = 1e-05
Identities = 89/433 (20%), Positives = 195/433 (45%), Gaps = 52/433 (12%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQ----LRQTRNRVAKMDKQLREAEASIT 305
EN K E E+ + +K++ T TE Q ++Q +R+ +++K+++ + +
Sbjct: 215 ENKKHQELFVDICSEKDNLREELKKR-TETEKQHMNTIKQLESRIEELNKEVKASRDKLI 273
Query: 306 SLTGTVKMLEDQSRQKEVQ-LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
+ T K Q ++ Q +E +K E+ + E + ++ + E L+ +++
Sbjct: 274 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRG----EKESLDLRKEK 329
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL-QDSRNAIEELQAK 423
E L + + A ++LE++ + K+ QE+ + + E KE T L ++ E++ +
Sbjct: 330 ETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQL-YETKEGETTRLIREIDKLKEDINSH 388
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG---IQQK 480
+I+++ ++ + E+D E TK+ L+ T ++T K E + K I+
Sbjct: 389 VIKVKWAQNK----LKAEMDSHKE---TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTY 441
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI---------- 530
+E + E+ K+++ EL K ++ ++ + +++L+ RT
Sbjct: 442 QESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTL 501
Query: 531 ---ANCQESPNGISYQDLQQ--EIMDLK----MKLLDVVHRNEELSEILAKKDQELEQQD 581
C E + +L + EI++ + LLD V ++L E L + QE+E
Sbjct: 502 RTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 561
Query: 582 KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
+ ++ LIN L+ K+ E SR+ + + L R+ + N Q+ ++++ +Q
Sbjct: 562 EE-------VESLNSLINDLQ-KDIEGSRKRES--ELLLFTERLTSK-NAQLQSESNSLQ 610
Query: 642 ELFATLENKQQQI 654
F + + Q+
Sbjct: 611 SQFDKVSCSESQL 623
>BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.
Length = 1004
Score = 74.9 bits (176), Expect = 9e-13
Identities = 109/423 (25%), Positives = 188/423 (44%), Gaps = 42/423 (9%)
Query: 186 LRELKTQAEDAVNTVTDLS--KRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEI 242
LR+ + E N + LS K H+ T L+RE+ KL++D+ + + +
Sbjct: 442 LRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWA 501
Query: 243 R-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ +L++E ++ K E + +L E T KLT + + Q R M K +E+E
Sbjct: 502 QNKLKAEMDSHK---ETKDKLKETTT-------KLTQAKEEADQIRKNCQDMIKTYQESE 551
Query: 302 ASITS-----LTGTVKMLEDQSRQKEVQLEARARKLRE------SLKTGEVTTSQLIQQR 350
++ L T LE Q ++K QLE K++E + K G L +
Sbjct: 552 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 611
Query: 351 DSLQAEVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERT 406
L+ E L + ++ K + + K+ IQ L + +K T LQEQ + K+EIE LKE
Sbjct: 612 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-TADQLQEQLQRGKQEIENLKE-- 668
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E++ + I +LQ I K + L TER A+LQ+ +L+ D+V+ +
Sbjct: 669 --EVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSE 726
Query: 467 REKESENKIGIQQKLAAE-LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA 525
+ +S+ + Q + E L KEE + K ++QT + + E K + + V +L+
Sbjct: 727 SQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQ--VEELKD 784
Query: 526 HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
T Q + S +DL +++ + K LD V E+ + + N+R
Sbjct: 785 ELVT----QRRKHASSIKDLTKQLQQARRK-LDQVESGSYDKEVSSMGSRSSSSGSLNAR 839
Query: 586 GQA 588
A
Sbjct: 840 SSA 842
Score = 63.3 bits (147), Expect = 3e-09
Identities = 99/433 (22%), Positives = 184/433 (42%), Gaps = 21/433 (4%)
Query: 242 IRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
I +++S S + LEE+ EL A+ + + E L V DK L++
Sbjct: 256 ISKIKSVSASEDLLEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCV--QDKYLQQEH 313
Query: 302 ASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
+ K E D +K+ L +K E+ K T QL + + L EV
Sbjct: 314 IIKKLIKENKKHQELFVDICSEKD-NLREELKKRTETEKQHMNTIKQLESRIEELNKEVK 372
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK----ERTETELQDSR 414
+ Q+ V K+A+QQL +++ Q ++CE ++E E R E E D R
Sbjct: 373 ASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLR 432
Query: 415 NAIEELQAKI----IELEKSKPNPDLPTEREIDLWAELQATK--ETLRVTEDEVTTCKRE 468
E L+ K+ ELEK+ N +E +L TK ET R+ E+ K +
Sbjct: 433 KEKETLEKKLRDANKELEKN-TNKIKQLSQEKGRLHQLYETKEGETTRLIR-EIDKLKED 490
Query: 469 KESE-NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
S K+ Q KL AE+ + +E K++ T +L + + +Q + ++ Q
Sbjct: 491 INSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQES 550
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+N ++ ++ +L++++ + K L++ H + E L + +E + + R
Sbjct: 551 EEIKSNELDAKLRVTKGELEKQMQE-KSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRT 609
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ + ++ +K E A Q+L +++ D++ +Q+ EI+ L
Sbjct: 610 KVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEE 669
Query: 647 LENKQQQIHRLEK 659
+E+ I+ L+K
Sbjct: 670 VESLNSLINDLQK 682
Score = 51.2 bits (117), Expect = 1e-05
Identities = 89/433 (20%), Positives = 195/433 (45%), Gaps = 52/433 (12%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQ----LRQTRNRVAKMDKQLREAEASIT 305
EN K E E+ + +K++ T TE Q ++Q +R+ +++K+++ + +
Sbjct: 321 ENKKHQELFVDICSEKDNLREELKKR-TETEKQHMNTIKQLESRIEELNKEVKASRDQLI 379
Query: 306 SLTGTVKMLEDQSRQKEVQ-LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
+ T K Q ++ Q +E +K E+ + E + ++ + E L+ +++
Sbjct: 380 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRG----EKESLDLRKEK 435
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL-QDSRNAIEELQAK 423
E L + + A ++LE++ + K+ QE+ + + E KE T L ++ E++ +
Sbjct: 436 ETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQL-YETKEGETTRLIREIDKLKEDINSH 494
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIG---IQQK 480
+I+++ ++ + E+D E TK+ L+ T ++T K E + K I+
Sbjct: 495 VIKVKWAQNK----LKAEMDSHKE---TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTY 547
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI---------- 530
+E + E+ K+++ EL K ++ ++ + +++L+ RT
Sbjct: 548 QESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTL 607
Query: 531 ---ANCQESPNGISYQDLQQ--EIMDLK----MKLLDVVHRNEELSEILAKKDQELEQQD 581
C E + +L + EI++ + LLD V ++L E L + QE+E
Sbjct: 608 RTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 667
Query: 582 KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
+ ++ LIN L+ K+ E SR+ + + L R+ + N Q+ ++++ +Q
Sbjct: 668 EE-------VESLNSLINDLQ-KDIEGSRKRES--ELLLFTERLTSK-NAQLQSESNSLQ 716
Query: 642 ELFATLENKQQQI 654
F + + Q+
Sbjct: 717 SQFDKVSCSESQL 729
>AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen
HD-CL-01 protein.
Length = 613
Score = 74.9 bits (176), Expect = 9e-13
Identities = 109/423 (25%), Positives = 188/423 (44%), Gaps = 42/423 (9%)
Query: 186 LRELKTQAEDAVNTVTDLS--KRACHER-RTLIAVGEALVREVAKLRQDVETRNVMIDEI 242
LR+ + E N + LS K H+ T L+RE+ KL++D+ + + +
Sbjct: 153 LRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWA 212
Query: 243 R-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ +L++E ++ K E + +L E T KLT + + Q R M K +E+E
Sbjct: 213 QNKLKAEMDSHK---ETKDKLKETTT-------KLTQAKEEADQIRKNCQDMIKTYQESE 262
Query: 302 ASITS-----LTGTVKMLEDQSRQKEVQLEARARKLRE------SLKTGEVTTSQLIQQR 350
++ L T LE Q ++K QLE K++E + K G L +
Sbjct: 263 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 322
Query: 351 DSLQAEVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERT 406
L+ E L + ++ K + + K+ IQ L + +K T LQEQ + K+EIE LKE
Sbjct: 323 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVK-TADQLQEQLQRGKQEIENLKE-- 379
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E++ + I +LQ I K + L TER A+LQ+ +L+ D+V+ +
Sbjct: 380 --EVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSE 437
Query: 467 REKESENKIGIQQKLAAE-LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA 525
+ +S+ + Q + E L KEE + K ++QT + + E K + + V +L+
Sbjct: 438 SQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQ--VEELKD 495
Query: 526 HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
T Q + S +DL +++ + K LD V E+ + + N+R
Sbjct: 496 ELVT----QRRKHASSIKDLTKQLQQARRK-LDQVESGSYDKEVSSMGSRSSSSGSLNAR 550
Query: 586 GQA 588
A
Sbjct: 551 SSA 553
Score = 62.5 bits (145), Expect = 5e-09
Identities = 85/425 (20%), Positives = 197/425 (46%), Gaps = 36/425 (8%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQ----LRQTRNRVAKMDKQLREAEASIT 305
EN K E E+ + +K++ T TE Q ++Q +R+ +++K+++ + +
Sbjct: 32 ENKKHQELFVDICSEKDNLREELKKR-TETEKQHMNTIKQLESRIEELNKEVKASRDKLI 90
Query: 306 SLTGTVKMLEDQSRQKEVQ-LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
+ T K Q ++ Q +E +K E+ + E + ++ + E L+ +++
Sbjct: 91 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRG----EKESLDLRKEK 146
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL-QDSRNAIEELQAK 423
E L + + A ++LE++ + K+ QE+ + + E KE T L ++ E++ +
Sbjct: 147 ETLEKKLRDANKELEKNTNKIKQLSQEKGRL-HQLYETKEGETTRLIREIDKLKEDINSH 205
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK---IGIQQK 480
+I+++ ++ + E+D E TK+ L+ T ++T K E + K I+
Sbjct: 206 VIKVKWAQNK----LKAEMDSHKE---TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTY 258
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGI 540
+E + E+ K+++ EL K ++ ++ + +++L+ RT + +
Sbjct: 259 QESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTL 318
Query: 541 -----SYQDLQQEIMDLKMKLLDVVHRNE-ELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+D + D K ++++R + E+ +L K + Q++ RG+ + ++
Sbjct: 319 RTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 378
Query: 595 EEL--INVLKN---KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
EE+ +N L N K+ E SR+ + + L R+ + N Q+ ++++ +Q F +
Sbjct: 379 EEVESLNSLINDLQKDIEGSRKRES--ELLLFTERLTSK-NAQLQSESNSLQSQFDKVSC 435
Query: 650 KQQQI 654
+ Q+
Sbjct: 436 SESQL 440
Score = 60.1 bits (139), Expect = 3e-08
Identities = 83/369 (22%), Positives = 167/369 (45%), Gaps = 24/369 (6%)
Query: 312 KMLEDQSRQKEVQLEARARK--LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI----E 365
K++++ + +E+ ++ + K LRE LK T Q + L++ + E +++ +
Sbjct: 28 KLIKENKKHQELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRD 87
Query: 366 KLTVQH---KSAIQQLEEDLKQTKRALQEQCEITKREIELK----ERTETELQDSRNAIE 418
KL Q K+A+QQL +++ Q ++CE ++E E R E E D R E
Sbjct: 88 KLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKE 147
Query: 419 ELQAKI----IELEKSKPNPDLPTEREIDLWAELQATK--ETLRVTEDEVTTCKREKESE 472
L+ K+ ELEK+ N +E +L TK ET R+ E+ K + S
Sbjct: 148 TLEKKLRDANKELEKN-TNKIKQLSQEKGRLHQLYETKEGETTRLIR-EIDKLKEDINSH 205
Query: 473 -NKI-GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
K+ Q KL AE+ + +E K++ T +L + + +Q + ++ Q
Sbjct: 206 VIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIK 265
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
+N ++ ++ +L++++ + K L++ H + E L + +E + + R + +
Sbjct: 266 SNELDAKLRVTKGELEKQMQE-KSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKC 324
Query: 591 IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
++ +K E A Q+L +++ D++ +Q+ EI+ L +E+
Sbjct: 325 LEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESL 384
Query: 651 QQQIHRLEK 659
I+ L+K
Sbjct: 385 NSLINDLQK 393
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 74.5 bits (175), Expect = 1e-12
Identities = 107/498 (21%), Positives = 221/498 (44%), Gaps = 34/498 (6%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
ALR+ ++ + + + + A + + L A + + + ++++ R + + ++E
Sbjct: 767 ALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE 826
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
SE K E ++ +E+ A+ + E+ + + +++T N++ + ++Q + +
Sbjct: 827 NLSEVSQVKETLEKELQILKEKFAEAS--EEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 884
Query: 305 TSLTGTVKMLEDQSRQK---EVQLEARARKLR----ESLKTGEVTTSQLIQQRDSLQAEV 357
L + +E + R+K E QL KL E +K +SQL + D L+ +
Sbjct: 885 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE 944
Query: 358 LECKQQIEKLTVQHKSA--IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
+ ++ KLT +++A +Q+ ED+ T +A Q Q E K+ E K+ E +L D
Sbjct: 945 RDVEELQLKLTKANENASFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKELERKLSDLEK 1002
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+E + EL+ T+ + + LQ ++TL TED++ + E
Sbjct: 1003 KMETSHNQCQELKARYERATSETKTKHE--EILQNLQKTLLDTEDKLKGAREENS----- 1055
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G+ Q+L E L K+ K QT E +++ EQ + + + L+ +T A Q
Sbjct: 1056 GLLQEL--EELRKQADKAK-AAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQN 1110
Query: 536 SPNGISYQDLQQ-EIMDLKMKLLDVVHRNEE--LSEILAKKDQELEQQDKNSRGQARVIK 592
+ + +L+ E ++ +LL V ++ E EI K ++ + S Q +K
Sbjct: 1111 ELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVK 1170
Query: 593 IREEL----INVLKNKETEQSRELA--ALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ EEL V +++ E+ R + L + + + + + +++ A+ I A
Sbjct: 1171 LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSAL 1230
Query: 647 LENKQQQIHRLEKIVLAL 664
L K ++ +L V L
Sbjct: 1231 LTEKDAELEKLRNEVTVL 1248
Score = 71.3 bits (167), Expect = 1e-11
Identities = 110/521 (21%), Positives = 227/521 (43%), Gaps = 46/521 (8%)
Query: 164 TDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL-- 221
T GD+ + + EL +L KT+A+ + D E+ ++ + + L
Sbjct: 451 TKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLAL 510
Query: 222 -VREVAKLRQ---------DVETRNVMIDEIRELRSESENTKALEEMR------HELDEE 265
V+EVA+LR+ DV+ ++ EI L+ + E T+ + H E
Sbjct: 511 RVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGARE 570
Query: 266 RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK--MLEDQSRQKEV 323
T + IK T TE ++ + +K++ +E I ++ + Q +E+
Sbjct: 571 ETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL 630
Query: 324 QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLK 383
++ E+ + E+ T Q+ + R Q E+ + Q + H ++ L L
Sbjct: 631 KVSFSKGLGTETAEFAELKT-QIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLM 689
Query: 384 QTKRALQEQCEITKREIELKERTE-TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI 442
+ + + E + +++ E E++D+ N ++E + K+ ELE + + T+
Sbjct: 690 KVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVID 749
Query: 443 DLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL 502
+ ++L+AT+E L + D + E +SE K QQ AAE QI+ E+
Sbjct: 750 NFTSQLKATEEKL-LDLDALRKASSEGKSEMKKLRQQLEAAE----------KQIKHLEI 798
Query: 503 IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVV 560
KN + ++ I R+LQ + N QE+ + +S + L++E+ LK K +
Sbjct: 799 EKNAESSKASSI-----TRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEAS 853
Query: 561 HRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINV-LKNKE-TEQSRELAALQQ 617
+ + + +L Q+++ + + + K+RE L ++ K +E E+ +L ++
Sbjct: 854 EEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKE 913
Query: 618 DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
LE+ + E+ K + ++ ++ L K++ + L+
Sbjct: 914 KLEND---IAEIMKMSGDNSSQLTKMNDELRLKERDVEELQ 951
Score = 62.5 bits (145), Expect = 5e-09
Identities = 116/495 (23%), Positives = 210/495 (42%), Gaps = 51/495 (10%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR 243
G L E ++ ++ T L + A E++ I E L+ E R +V + EI
Sbjct: 334 GLLTETSSRYARKISGTTALQE-ALKEKQQHI---EQLLAERDLERAEVAKATSHVGEIE 389
Query: 244 E---LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+ L + + LE + ++D+ RT A + +QL + + +V D Q R
Sbjct: 390 QELALARDGHDQHVLE-LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVE--DLQFRVE 446
Query: 301 EASITSLTGTVKMLEDQSRQKEVQL-----EARARKLRESLKTGEVTT----SQLIQQRD 351
E SIT + + +R KE++ + +A KL+ L+ V T S++++
Sbjct: 447 EESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEK 506
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
L V E + +L + + L Q +LQE+ E+T+ + +R T L+
Sbjct: 507 DLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTD---HQREITSLK 563
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQ-ATKETLRVTEDEVTTCKREKE 470
+ A EE K I+ + L E E L ++L+ A KE D + K +
Sbjct: 564 EHFGAREETHQKEIKALYT-ATEKLSKENE-SLKSKLEHANKE----NSDVIALWK--SK 615
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
E I Q+ EL K + +T E + E+ + Y+ + +LQ
Sbjct: 616 LETAIASHQQAMEEL--KVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQ------ 667
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-----DQEL-EQQDKNS 584
N Q+S ++++ L+ KL+ V+ E E + K DQ L E +D +
Sbjct: 668 -NQQDSERAAHAKEMEA----LRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLN 722
Query: 585 RGQARVIKIRE-ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
+ Q IK++E E++ N++T+ + + E ++ +D + K + E+++L
Sbjct: 723 KLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKL 782
Query: 644 FATLENKQQQIHRLE 658
LE ++QI LE
Sbjct: 783 RQQLEAAEKQIKHLE 797
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 74.5 bits (175), Expect = 1e-12
Identities = 107/498 (21%), Positives = 221/498 (44%), Gaps = 34/498 (6%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
ALR+ ++ + + + + A + + L A + + + ++++ R + + ++E
Sbjct: 732 ALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE 791
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
SE K E ++ +E+ A+ + E+ + + +++T N++ + ++Q + +
Sbjct: 792 NLSEVSQVKETLEKELQILKEKFAEAS--EEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 849
Query: 305 TSLTGTVKMLEDQSRQK---EVQLEARARKLR----ESLKTGEVTTSQLIQQRDSLQAEV 357
L + +E + R+K E QL KL E +K +SQL + D L+ +
Sbjct: 850 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE 909
Query: 358 LECKQQIEKLTVQHKSA--IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
+ ++ KLT +++A +Q+ ED+ T +A Q Q E K+ E K+ E +L D
Sbjct: 910 RDVEELQLKLTKANENASFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKELERKLSDLEK 967
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+E + EL+ T+ + + LQ ++TL TED++ + E
Sbjct: 968 KMETSHNQCQELKARYERATSETKTKHE--EILQNLQKTLLDTEDKLKGAREENS----- 1020
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G+ Q+L E L K+ K QT E +++ EQ + + + L+ +T A Q
Sbjct: 1021 GLLQEL--EELRKQAEKAK-AAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQN 1075
Query: 536 SPNGISYQDLQQ-EIMDLKMKLLDVVHRNEE--LSEILAKKDQELEQQDKNSRGQARVIK 592
+ + +L+ E ++ +LL V ++ E EI K ++ + S Q +K
Sbjct: 1076 ELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVK 1135
Query: 593 IREEL----INVLKNKETEQSRELA--ALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ EEL V +++ E+ R + L + + + + + +++ A+ I A
Sbjct: 1136 LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSAL 1195
Query: 647 LENKQQQIHRLEKIVLAL 664
L K ++ +L V L
Sbjct: 1196 LTEKDAELEKLRNEVTVL 1213
Score = 71.7 bits (168), Expect = 8e-12
Identities = 105/499 (21%), Positives = 220/499 (44%), Gaps = 46/499 (9%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL---VREVAKLRQ---------DVE 233
+ +L+ + E+ T DL E+ ++ + + L V+EVA+LR+ DV+
Sbjct: 438 VEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVD 497
Query: 234 TRNVMIDEIRELRSESENTKALEEMR------HELDEERTAKLAIKEKLTTTESQLRQTR 287
++ EI L+ + E T+ + H E T + IK T TE ++
Sbjct: 498 MSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENE 557
Query: 288 NRVAKMDKQLREAEASITSLTGTVK--MLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+ +K++ +E I ++ + Q +E+++ E+ + E+ T Q
Sbjct: 558 SLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKT-Q 616
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+ + R Q E+ + Q + H ++ L L + + + E + +++ E
Sbjct: 617 IEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAED 676
Query: 406 TE-TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTT 464
E++D+ N ++E + K+ ELE + + T+ + ++L+AT+E L + D +
Sbjct: 677 QHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKL-LDLDALRK 735
Query: 465 CKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQ 524
E +SE K QQ AAE QI+ E+ KN + ++ I R+LQ
Sbjct: 736 ASSEGKSEMKKLRQQLEAAE----------KQIKHLEIEKNAESSKASSI-----TRELQ 780
Query: 525 AHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
+ N QE+ + +S + L++E+ LK K + + + + +L Q+++
Sbjct: 781 GRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEE 840
Query: 583 N-SRGQARVIKIREELINV-LKNKE-TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ + + K+RE L ++ K +E E+ +L ++ LE+ + E+ K + +
Sbjct: 841 QFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEND---IAEIMKMSGDNSSQ 897
Query: 640 IQELFATLENKQQQIHRLE 658
+ ++ L K++ + L+
Sbjct: 898 LTKMNDELRLKERDVEELQ 916
Score = 57.2 bits (132), Expect = 2e-07
Identities = 126/550 (22%), Positives = 237/550 (43%), Gaps = 77/550 (14%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR 243
G L E ++ ++ T L + A E++ I E L+ E R +V + EI
Sbjct: 334 GLLTETSSRYARKISGTTALQE-ALKEKQQHI---EQLLAERDLERAEVAKATSHVGEIE 389
Query: 244 E---LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+ L + + LE + ++D+ RT A + +QL + + +V D Q R
Sbjct: 390 QELALARDGHDQHVLE-LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVE--DLQFRVE 446
Query: 301 EASITSLTGTVKMLEDQSR----QKEVQLEARA-----RKLRESLKTGEVTTS-QLIQQR 350
E SIT V + ++SR +K++ L + R+L + G+V S L+Q+
Sbjct: 447 EESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEI 506
Query: 351 DSL-----------QAEVLECKQQIEKLTVQHKSAIQQL---EEDLKQTKRALQEQCEIT 396
SL Q E+ K+ H+ I+ L E L + +L+ + E
Sbjct: 507 SSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHA 566
Query: 397 KRE----IEL-KERTETELQDSRNAIEELQ-----------AKIIELEKSKPNPDLPTER 440
+E I L K + ET + + A+EEL+ A+ EL+ L +
Sbjct: 567 NKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQH 626
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKRE---KESENKI-GIQQKL-AAE---LLNKEEII 492
EI+ Q ++ E E K KE EN + I+ KL AE L+ E+ +
Sbjct: 627 EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTL 686
Query: 493 GKMQ---IQTREL-IKNIKLNEQ-KVIQ--------YEQYVRDLQAHNRTIANCQESPNG 539
K+Q I+ +EL + K NEQ KVI E+ + DL A + + +
Sbjct: 687 NKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKK 746
Query: 540 ISYQ--DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ Q +++I L+++ + ++ L ++ +L +N ++V + E+
Sbjct: 747 LRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKE 806
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAKADEIQELFATLENK-QQQ 653
+ +LK K E S E ++Q+ ++ + + + +Q +++ ++++E A +E K +++
Sbjct: 807 LQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREK 866
Query: 654 IHRLEKIVLA 663
R E+++ A
Sbjct: 867 DEREEQLIKA 876
Score = 50.8 bits (116), Expect = 2e-05
Identities = 75/381 (19%), Positives = 166/381 (43%), Gaps = 26/381 (6%)
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
A++ + TT + L+ R+ A + +S++S +L + S + ++
Sbjct: 295 AVRRVMATTSASLK--RSPSASSLSSMSSVASSVSSRPSRTGLLTETSSRYARKISGTTA 352
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
L+E+LK + QL+ +RD +AEV + + ++ + A ++ + + + +
Sbjct: 353 -LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMD 411
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + K +L++ + +E+LQ ++ E +K + ++ T E EL+
Sbjct: 412 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELE- 470
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
+ L + EV +R ES NK ++ LL + I +Q E ++ + +
Sbjct: 471 --KDLALRVQEVAELRRRLES-NKPAGDVDMSLSLLQE---ISSLQ----EKLEVTRTDH 520
Query: 511 QKVIQ--YEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
Q+ I E + + H + I + + L +E LK KL H N+E S+
Sbjct: 521 QREITSLKEHFGAREETHQKEIKALYTAT-----EKLSKENESLKSKL---EHANKENSD 572
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRM-RIV 626
++A +LE + + +K+ + + + E ++ ++ D +H + +
Sbjct: 573 VIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQ 632
Query: 627 DEVNKQIAAKADEIQELFATL 647
++ + + AA A E++ L A L
Sbjct: 633 NQQDSERAAHAKEMEALRAKL 653
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 74.5 bits (175), Expect = 1e-12
Identities = 103/486 (21%), Positives = 214/486 (44%), Gaps = 31/486 (6%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 905 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLA 964
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 965 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 1022
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL----IQQRDSL 353
+++ + ++ +Q ++ + LE RKL LK + + L +Q + L
Sbjct: 1023 SKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKL 1082
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ + + QQ K+ + A+ QL++ LK+ + ++E E + E + + E D
Sbjct: 1083 KKKEFDINQQNSKIEDEQVLAL-QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDL 1141
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKES 471
+EE+ + LE++ + E AE Q + L + E T K+
Sbjct: 1142 SRELEEISER---LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1198
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNR 528
+ + +L ++ N + + K++ + E + ++ N +++I+ + +L+ +R
Sbjct: 1199 ADSVA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKVSR 1252
Query: 529 TIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQA 588
T+ + Q + + ++ Q+ + D + + N ELS L +K+ + Q +RG+
Sbjct: 1253 TLED-QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEKEALISQL---TRGKL 1308
Query: 589 RVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATL 647
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + +
Sbjct: 1309 SYTQQMEDLKRQLE-EEGKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKA 1366
Query: 648 ENKQQQ 653
++ Q
Sbjct: 1367 NSEVAQ 1372
Score = 68.9 bits (161), Expect = 6e-11
Identities = 85/435 (19%), Positives = 195/435 (44%), Gaps = 36/435 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E IKE L +E++ ++ ++ + ++ +
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGR-------IKETLEKSEARRKELEEKMVSLLQEKNDL 889
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 949
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 950 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1009
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L KSK + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1010 DDLQAEEDKVNTLSKSK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 1062
Query: 475 IGIQ--QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV--IQYEQYVRDLQAHNRTI 530
+ + L + L EE + K + + +N K+ +++V +Q ++ +++ QA +
Sbjct: 1063 LTQESIMDLENDKLQLEEKLKKKEFDINQ--QNSKIEDEQVLALQLQKKLKENQARIEEL 1120
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSR 585
E+ + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 1121 EEELEAER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRR 1178
Query: 586 GQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 1179 DLEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTS 1235
Query: 646 TLENKQQQIHRLEKI 660
+E + LEK+
Sbjct: 1236 NMEQIIKAKANLEKV 1250
Score = 67.3 bits (157), Expect = 2e-10
Identities = 92/461 (19%), Positives = 202/461 (43%), Gaps = 39/461 (8%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESEN-TKALEEMRHELDEERTAKLAIKEK 275
V + L +E ++ + +++ +++I + ++ E ++ LE+ +E +
Sbjct: 1215 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLND 1274
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLT----GTVKMLEDQSRQKEVQLEAR--- 328
TT ++L QT N ++ +QL E EA I+ LT + +ED RQ E + +A+
Sbjct: 1275 FTTQRAKL-QTEN--GELSRQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNAL 1331
Query: 329 ------ARK----LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL 378
AR LRE + ++L + +EV +C+ + E +Q +++
Sbjct: 1332 AHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEEA 1391
Query: 379 EEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT 438
++ L Q + +E E + E+T+ LQ N IE+L ++++E+S
Sbjct: 1392 KKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQ---NEIEDL---MVDVERSNAAAAALD 1445
Query: 439 EREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGK--- 494
+++ + L K+ ++ E+ + ++E S + + K A E L E +
Sbjct: 1446 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1505
Query: 495 -MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLK 553
+Q + +L + + + V + E+ + L+ + + E S + + +I+ +
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEA-SLEHEEGKILRAQ 1564
Query: 554 MKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELA 613
++ + E+ LA+KD+E+EQ +N + RV+ + ++ E R
Sbjct: 1565 LEFNQI---KAEIERKLAEKDEEMEQAKRNHQ---RVVDSLQTSLDAETRSRNEVLRVKK 1618
Query: 614 ALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1659
Score = 58.4 bits (135), Expect = 8e-08
Identities = 96/470 (20%), Positives = 198/470 (42%), Gaps = 46/470 (9%)
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSE-----SENTKALEEMRHELDEERTAKLAIKEK 275
L ++ K D+ +N I++ + L + EN +EE+ EL+ ERTA+ +++
Sbjct: 1078 LEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKL 1137
Query: 276 LTTTESQLRQTRNRVAKM----DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
+ +L + R+ + Q+ + + LE+ + Q E A +K
Sbjct: 1138 RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1197
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE 391
+S+ L + + L+ E E K +++ +T + I+ + +L++ R L++
Sbjct: 1198 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKA-KANLEKVSRTLED 1256
Query: 392 QCEITKREIELKERT-----------ETELQDSRNAIEELQAKIIELEKSKPN-----PD 435
Q + ++E +R+ +TE + +EE +A I +L + K + D
Sbjct: 1257 QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEKEALISQLTRGKLSYTQQMED 1316
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
L + E + A+ A L+ + + + E E + + + N E +
Sbjct: 1317 LKRQLEEEGKAK-NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRT 1375
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ +T + + +L E K + Q ++D + + N + S + LQ EI DL
Sbjct: 1376 KYETDAIQRTEELEEAKK-KLAQRLQDAEEAVEAV-NAKCSSLEKTKHRLQNEIEDL--- 1430
Query: 556 LLDVVHRNEELSEILAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSR 610
++DV R+ + L KK + ++ + K Q+ + ++E ++ TE +
Sbjct: 1431 MVDV-ERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFK 1485
Query: 611 ELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
A ++ LEH + NK + +EI +L L + +H LEK+
Sbjct: 1486 LKNAYEESLEH-LETFKRENKNLQ---EEISDLTEQLGEGGKNVHELEKV 1531
Score = 57.2 bits (132), Expect = 2e-07
Identities = 117/557 (21%), Positives = 235/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL ++ + + + Y + E
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANL----EKVSRTLEDQANEYRVKLEE 1267
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
+L + TQ +LS R E+ LI+ L R Q +E ++E
Sbjct: 1268 AQRSLNDFTTQRAKLQTENGELS-RQLEEKEALIS---QLTRGKLSYTQQMEDLKRQLEE 1323
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E ++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 1324 --EGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDA 1381
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L++AE ++ ++ LE + + ++E L ++
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1437
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1438 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1497
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + E + ELEK + ++ +++L + L+ + +L
Sbjct: 1498 ETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEV---EKLELQSALEEAEASLE 1554
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAE-------LLNKEEIIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + N + ++ +Q + +N
Sbjct: 1555 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEV 1613
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1614 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1668
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQA-RVIKIREELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A R + E + +L ++ T +
Sbjct: 1669 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQ 1728
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 1729 KKKMDADLSQLQSEVEE 1745
Score = 54.4 bits (125), Expect = 1e-06
Identities = 92/453 (20%), Positives = 186/453 (41%), Gaps = 25/453 (5%)
Query: 219 EALVREVAKLRQD-VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLT 277
EA + K D V ID ++ ++ + E K+ E + ELD+ + I +
Sbjct: 1188 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS--EFKLELDDVTSNMEQIIKAKA 1245
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
E R ++ + +L EA+ S+ T L+ ++ + QLE + L L
Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEK-EALISQLT 1304
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE-QCEIT 396
G+++ +Q ++ E + K + + L E ++ A E Q ++
Sbjct: 1305 RGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLS 1364
Query: 397 KREIELKE-RTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
K E+ + RT+ E D+ EEL+ +L + + + E + L+ TK L
Sbjct: 1365 KANSEVAQCRTKYE-TDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRL 1423
Query: 456 R-VTEDEVTTCKREKESENKIGIQQ----KLAAELLNK-EEIIGKMQIQTRELIKNIKLN 509
+ ED + +R + + +Q K+ AE K EE +++ +E +++
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKE-ARSLSTE 1482
Query: 510 EQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNEEL 566
K+ YE+ + L+ R N QE + ++ Q + + + +L+ + EL
Sbjct: 1483 LFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLEL 1542
Query: 567 SEILAKKDQELEQQD-KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
L + + LE ++ K R Q +I+ E+ L K+ E ++Q + R+
Sbjct: 1543 QSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE-------MEQAKRNHQRV 1595
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
VD + + A+ E+ + + ++ +E
Sbjct: 1596 VDSLQTSLDAETRSRNEVLRVKKKMEGDLNEME 1628
Score = 54.4 bits (125), Expect = 1e-06
Identities = 87/503 (17%), Positives = 212/503 (42%), Gaps = 34/503 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1502
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + E+ ++R + E K ALEE L+ E L
Sbjct: 1503 ENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILR 1562
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1563 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVK-K 1618
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1677
Query: 391 EQCEITKREIELKERTETELQDSRN-AIEEL--QAKIIELEKSKPNPDLPTEREIDLWAE 447
+ + + E+E + + SR A EL ++ ++L S+ + ++++D A+
Sbjct: 1678 RRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMD--AD 1735
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK 507
L + + E+ V C+ +E K + AE L KE+ T ++ +K
Sbjct: 1736 LSQLQSEV---EEAVQECRNAEEKAKKAITHAAMMAEELKKEQ-------DTSAHLERMK 1785
Query: 508 LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS 567
N EQ ++DLQ Q L+ + +L+ +L RN E
Sbjct: 1786 KN------MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESV 1839
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
+ + K ++ +++ + + + ++L++ L+ K R+ ++ +
Sbjct: 1840 KGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFR 1899
Query: 628 EVNKQIAAKADEIQELFATLENK 650
+V ++ +A+E ++ + NK
Sbjct: 1900 KVQHEL-DEAEERADIAESQVNK 1921
Score = 45.6 bits (103), Expect = 6e-04
Identities = 60/296 (20%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1638 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1696
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + D ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1697 TERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEK 1756
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1757 AKKAITHAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1813
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1814 LQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKL 1873
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1874 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1925
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 74.5 bits (175), Expect = 1e-12
Identities = 107/498 (21%), Positives = 221/498 (44%), Gaps = 34/498 (6%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
ALR+ ++ + + + + A + + L A + + + ++++ R + + ++E
Sbjct: 778 ALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE 837
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
SE K E ++ +E+ A+ + E+ + + +++T N++ + ++Q + +
Sbjct: 838 NLSEVSQVKETLEKELQILKEKFAEAS--EEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 895
Query: 305 TSLTGTVKMLEDQSRQK---EVQLEARARKLR----ESLKTGEVTTSQLIQQRDSLQAEV 357
L + +E + R+K E QL KL E +K +SQL + D L+ +
Sbjct: 896 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE 955
Query: 358 LECKQQIEKLTVQHKSA--IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
+ ++ KLT +++A +Q+ ED+ T +A Q Q E K+ E K+ E +L D
Sbjct: 956 RDVEELQLKLTKANENASFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKELERKLSDLEK 1013
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+E + EL+ T+ + + LQ ++TL TED++ + E
Sbjct: 1014 KMETSHNQCQELKARYERATSETKTKHE--EILQNLQKTLLDTEDKLKGAREENS----- 1066
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G+ Q+L E L K+ K QT E +++ EQ + + + L+ +T A Q
Sbjct: 1067 GLLQEL--EELRKQADKAK-AAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQN 1121
Query: 536 SPNGISYQDLQQ-EIMDLKMKLLDVVHRNEE--LSEILAKKDQELEQQDKNSRGQARVIK 592
+ + +L+ E ++ +LL V ++ E EI K ++ + S Q +K
Sbjct: 1122 ELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVK 1181
Query: 593 IREEL----INVLKNKETEQSRELA--ALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ EEL V +++ E+ R + L + + + + + +++ A+ I A
Sbjct: 1182 LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSAL 1241
Query: 647 LENKQQQIHRLEKIVLAL 664
L K ++ +L V L
Sbjct: 1242 LTEKDAELEKLRNEVTVL 1259
Score = 70.9 bits (166), Expect = 1e-11
Identities = 103/480 (21%), Positives = 216/480 (45%), Gaps = 36/480 (7%)
Query: 186 LRELKTQAEDAVNTVTDLSKRA-CHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
+ EL+ V V +L +R ++ + + +L++E++ L++ +E D RE
Sbjct: 512 IMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRT--DHQRE 569
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+ S E+ A EE H+ +E A EKL+ L+ +++ +K+ + A
Sbjct: 570 ITSLKEHFGAREET-HQ--KEIKALYTATEKLSKENESLK---SKLEHANKENSDVIALW 623
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
S T + Q +E+++ E+ + E+ T Q+ + R Q E+ + Q
Sbjct: 624 KSKLETA-IASHQQAMEELKVSFSKGLGTETAEFAELKT-QIEKMRLDYQHEIENLQNQQ 681
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTE-TELQDSRNAIEELQAK 423
+ H ++ L L + + + E + +++ E E++D+ N ++E + K
Sbjct: 682 DSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIK 741
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
+ ELE + + T+ + ++L+AT+E L + D + E +SE K QQ AA
Sbjct: 742 VKELEVLQAKCNEQTKVIDNFTSQLKATEEKL-LDLDALRKASSEGKSEMKKLRQQLEAA 800
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISY- 542
E QI+ E+ KN + ++ I R+LQ + N QE+ + +S
Sbjct: 801 E----------KQIKHLEIEKNAESSKASSI-----TRELQGRELKLTNLQENLSEVSQV 845
Query: 543 -QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINV 600
+ L++E+ LK K + + + + +L Q+++ + + + K+RE L ++
Sbjct: 846 KETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADM 905
Query: 601 -LKNKE-TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
K +E E+ +L ++ LE+ + E+ K + ++ ++ L K++ + L+
Sbjct: 906 EAKFREKDEREEQLIKAKEKLEND---IAEIMKMSGDNSSQLTKMNDELRLKERDVEELQ 962
Score = 64.1 bits (149), Expect = 2e-09
Identities = 109/505 (21%), Positives = 214/505 (42%), Gaps = 60/505 (11%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDE--ERTAKLAIKEKL 276
EA RE +L +E +++++ E TK E + ++ E E T ++
Sbjct: 418 EAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARI 477
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
E L + + K+ ++L + + S + LE + ++ R+L +
Sbjct: 478 KELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNK 537
Query: 337 KTGEVTTS-QLIQQRDSL-----------QAEVLECKQQIEKLTVQHKSAIQQL---EED 381
G+V S L+Q+ SL Q E+ K+ H+ I+ L E
Sbjct: 538 PAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEK 597
Query: 382 LKQTKRALQEQCEITKRE----IEL-KERTETELQDSRNAIEELQ-----------AKII 425
L + +L+ + E +E I L K + ET + + A+EEL+ A+
Sbjct: 598 LSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFA 657
Query: 426 ELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE---KESENKI-GIQQKL 481
EL+ L + EI+ Q ++ E E K KE EN + I+ KL
Sbjct: 658 ELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKL 717
Query: 482 -AAE---LLNKEEIIGKMQ---IQTREL-IKNIKLNEQ-KVIQ--------YEQYVRDLQ 524
AE L+ E+ + K+Q I+ +EL + K NEQ KVI E+ + DL
Sbjct: 718 DKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLD 777
Query: 525 AHNRTIANCQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
A + + + + Q +++I L+++ + ++ L ++ +L +
Sbjct: 778 ALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE 837
Query: 583 NSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAKADE 639
N ++V + E+ + +LK K E S E ++Q+ ++ + + + +Q +++ ++
Sbjct: 838 NLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEK 897
Query: 640 IQELFATLENK-QQQIHRLEKIVLA 663
++E A +E K +++ R E+++ A
Sbjct: 898 LRENLADMEAKFREKDEREEQLIKA 922
Score = 43.2 bits (97), Expect = 0.003
Identities = 77/358 (21%), Positives = 155/358 (43%), Gaps = 32/358 (8%)
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
A++ + TT + L+ R+ A + +S++S +L + S + ++
Sbjct: 295 AVRRVMATTSASLK--RSPSASSLSSMSSVASSVSSRPSRTGLLTETSSRYARKISGTTA 352
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
L+E+LK + QL+ +RD +AEV + + ++ + A ++ + + + +
Sbjct: 353 -LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMD 411
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + K +L++ + +E+LQ ++ E+S DL + +I E
Sbjct: 412 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRV--EEESITKGDLEQKSQISEDPENTQ 469
Query: 451 TK-ETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
TK E R+ E E + + +++ KL EL + + + EL K++ L
Sbjct: 470 TKLEHARIKELEQSLLFEKTKAD-------KLQRELEDTRVATVSEKSRIMELEKDLALR 522
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
Q+V + R L++ N+ + S L QEI L+ KL V R + EI
Sbjct: 523 VQEVAELR---RRLES-NKPAGDVDMS------LSLLQEISSLQEKL--EVTRTDHQREI 570
Query: 570 LAKKD-----QELEQQDKNSRGQA--RVIKIREELINVLKNKETEQSRELAALQQDLE 620
+ K+ +E Q++ + A ++ K E L + L++ E S +A + LE
Sbjct: 571 TSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLE 628
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 74.5 bits (175), Expect = 1e-12
Identities = 107/498 (21%), Positives = 221/498 (44%), Gaps = 34/498 (6%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
ALR+ ++ + + + + A + + L A + + + ++++ R + + ++E
Sbjct: 732 ALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE 791
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
SE K E ++ +E+ A+ + E+ + + +++T N++ + ++Q + +
Sbjct: 792 NLSEVSQVKETLEKELQILKEKFAEAS--EEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 849
Query: 305 TSLTGTVKMLEDQSRQK---EVQLEARARKLR----ESLKTGEVTTSQLIQQRDSLQAEV 357
L + +E + R+K E QL KL E +K +SQL + D L+ +
Sbjct: 850 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE 909
Query: 358 LECKQQIEKLTVQHKSA--IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
+ ++ KLT +++A +Q+ ED+ T +A Q Q E K+ E K+ E +L D
Sbjct: 910 RDVEELQLKLTKANENASFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKELERKLSDLEK 967
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+E + EL+ T+ + + LQ ++TL TED++ + E
Sbjct: 968 KMETSHNQCQELKARYERATSETKTKHE--EILQNLQKTLLDTEDKLKGAREENS----- 1020
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G+ Q+L E L K+ K QT E +++ EQ + + + L+ +T A Q
Sbjct: 1021 GLLQEL--EELRKQADKAK-AAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQN 1075
Query: 536 SPNGISYQDLQQ-EIMDLKMKLLDVVHRNEE--LSEILAKKDQELEQQDKNSRGQARVIK 592
+ + +L+ E ++ +LL V ++ E EI K ++ + S Q +K
Sbjct: 1076 ELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVK 1135
Query: 593 IREEL----INVLKNKETEQSRELA--ALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ EEL V +++ E+ R + L + + + + + +++ A+ I A
Sbjct: 1136 LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSAL 1195
Query: 647 LENKQQQIHRLEKIVLAL 664
L K ++ +L V L
Sbjct: 1196 LTEKDAELEKLRNEVTVL 1213
Score = 68.1 bits (159), Expect = 1e-10
Identities = 104/499 (20%), Positives = 218/499 (43%), Gaps = 46/499 (9%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEAL---VREVAKLRQ---------DVE 233
+ +L+ + E+ T DL E+ ++ + + L V+EVA+LR+ DV+
Sbjct: 438 VEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVD 497
Query: 234 TRNVMIDEIRELRSESENTKALEEMR------HELDEERTAKLAIKEKLTTTESQLRQTR 287
++ EI L+ + E T+ + H E T + IK T TE ++
Sbjct: 498 MSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENE 557
Query: 288 NRVAKMDKQLREAEASITSLTGTVK--MLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
+ +K++ +E I ++ + Q +E+++ E+ + E+ T Q
Sbjct: 558 SLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGAETAEFAELKT-Q 616
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+ + R Q E+ + Q H ++ L L + + + E + +++ E
Sbjct: 617 IEKMRLDYQHEIENLQNQQNSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAED 676
Query: 406 TE-TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTT 464
E++D+ N ++E + K+ ELE + + T+ + ++ +AT+E L + D +
Sbjct: 677 QHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQPKATEEKL-LDLDALRK 735
Query: 465 CKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQ 524
E +SE K QQ AAE QI+ E+ KN + ++ I R+LQ
Sbjct: 736 ASSEGKSEMKKLRQQLEAAE----------KQIKHLEIEKNAESSKASSI-----TRELQ 780
Query: 525 AHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
+ N QE+ + +S + L++E+ LK K + + + + +L Q+++
Sbjct: 781 GRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEE 840
Query: 583 N-SRGQARVIKIREELINV-LKNKE-TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ + + K+RE L ++ K +E E+ +L ++ LE+ + E+ K + +
Sbjct: 841 QFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLEND---IAEIMKMSGDNSSQ 897
Query: 640 IQELFATLENKQQQIHRLE 658
+ ++ L K++ + L+
Sbjct: 898 LTKMNDELRLKERDVEELQ 916
Score = 57.2 bits (132), Expect = 2e-07
Identities = 126/550 (22%), Positives = 237/550 (43%), Gaps = 77/550 (14%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR 243
G L E ++ ++ T L + A E++ I E L+ E R +V + EI
Sbjct: 334 GLLTETSSRYARKISGTTALQE-ALKEKQQHI---EQLLAERDLERAEVAKATSHVGEIE 389
Query: 244 E---LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+ L + + LE + ++D+ RT A + +QL + + +V D Q R
Sbjct: 390 QELALARDGHDQHVLE-LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVE--DLQFRVE 446
Query: 301 EASITSLTGTVKMLEDQSR----QKEVQLEARA-----RKLRESLKTGEVTTS-QLIQQR 350
E SIT V + ++SR +K++ L + R+L + G+V S L+Q+
Sbjct: 447 EESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEI 506
Query: 351 DSL-----------QAEVLECKQQIEKLTVQHKSAIQQL---EEDLKQTKRALQEQCEIT 396
SL Q E+ K+ H+ I+ L E L + +L+ + E
Sbjct: 507 SSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHA 566
Query: 397 KRE----IEL-KERTETELQDSRNAIEELQ-----------AKIIELEKSKPNPDLPTER 440
+E I L K + ET + + A+EEL+ A+ EL+ L +
Sbjct: 567 NKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGAETAEFAELKTQIEKMRLDYQH 626
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKRE---KESENKI-GIQQKL-AAE---LLNKEEII 492
EI+ Q ++ E E K KE EN + I+ KL AE L+ E+ +
Sbjct: 627 EIENLQNQQNSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTL 686
Query: 493 GKMQ---IQTREL-IKNIKLNEQ-KVIQ--------YEQYVRDLQAHNRTIANCQESPNG 539
K+Q I+ +EL + K NEQ KVI E+ + DL A + + +
Sbjct: 687 NKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQPKATEEKLLDLDALRKASSEGKSEMKK 746
Query: 540 ISYQ--DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ Q +++I L+++ + ++ L ++ +L +N ++V + E+
Sbjct: 747 LRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKE 806
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAKADEIQELFATLENK-QQQ 653
+ +LK K E S E ++Q+ ++ + + + +Q +++ ++++E A +E K +++
Sbjct: 807 LQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREK 866
Query: 654 IHRLEKIVLA 663
R E+++ A
Sbjct: 867 DEREEQLIKA 876
Score = 52.0 bits (119), Expect = 7e-06
Identities = 76/381 (19%), Positives = 165/381 (43%), Gaps = 26/381 (6%)
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
A++ + TT + L+ R+ A + S++S +L + S + ++
Sbjct: 295 AVRRVMATTSASLK--RSPSASSLSSMSSVAPSVSSRPSRTGLLTETSSRYARKISGTTA 352
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
L+E+LK + QL+ +RD +AEV + + ++ + A ++ + + + +
Sbjct: 353 -LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMD 411
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + K +L++ + +E+LQ ++ E +K + ++ T E EL+
Sbjct: 412 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELE- 470
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
+ L + EV +R ES NK ++ LL + I +Q E ++ + +
Sbjct: 471 --KDLALRVQEVAELRRRLES-NKPAGDVDMSLSLLQE---ISSLQ----EKLEVTRTDH 520
Query: 511 QKVIQ--YEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
Q+ I E + + H + I + + L +E LK KL H N+E S+
Sbjct: 521 QREITSLKEHFGAREETHQKEIKALYTAT-----EKLSKENESLKSKL---EHANKENSD 572
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRM-RIV 626
++A +LE + + +K+ + + + E ++ ++ D +H + +
Sbjct: 573 VIALWKSKLETAIASHQQAMEELKVSFSKGLGAETAEFAELKTQIEKMRLDYQHEIENLQ 632
Query: 627 DEVNKQIAAKADEIQELFATL 647
++ N + AA A E++ L A L
Sbjct: 633 NQQNSERAAHAKEMEALRAKL 653
>AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated
protein CEP110 protein.
Length = 994
Score = 74.5 bits (175), Expect = 1e-12
Identities = 115/516 (22%), Positives = 235/516 (45%), Gaps = 44/516 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE---- 241
L +LK+Q + L ++ H++ L + ++V+ A L++ + + E
Sbjct: 251 LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNH 310
Query: 242 IRELRSESENTKALE-EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
IRE++S E + E+ ++ E +T IK+++ E L+ +++K +L+
Sbjct: 311 IREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELQNI 370
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLE-ARARKLRESLKTGEVTT-SQLIQQRDSLQAEVL 358
+ ++ L+ Q Q+ +LE + L E L+ + SQ + Q ++L
Sbjct: 371 LDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLL 430
Query: 359 EC-KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-------TKREIELKERT---- 406
E K++IE++T + + A+Q E L + K LQE+C+I TKR + E
Sbjct: 431 ERDKREIERMTAESR-ALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKME 489
Query: 407 ETELQDSRNAIEELQAKIIELEKSK---------PNPDLPTEREI--DLWAELQATKETL 455
++ L+ + +LQ ++ +L + K L +RE L EL ++ L
Sbjct: 490 QSNLEKLDLNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHL 549
Query: 456 RVT-EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGK----MQIQTRELIKNIKLNE 510
+ +D + T K + ++ QK +E N+ E K Q Q + L I+ N+
Sbjct: 550 NLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENK 609
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR-NEELSEI 569
K++Q E + LQ + +ES S L+++ L+ +L D + ++ LS++
Sbjct: 610 LKLVQQEMMFQRLQKERES----EESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 665
Query: 570 LAKKD--QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
LA ++ + L+++++ + + + ++ + + E+S EL ALQ++ +
Sbjct: 666 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 725
Query: 628 EVNKQIAAKADEIQELFATL-ENKQQQIHRLEKIVL 662
+ Q + + ++ A+L E + Q +LEK +L
Sbjct: 726 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLL 761
Score = 70.1 bits (164), Expect = 2e-11
Identities = 109/520 (20%), Positives = 228/520 (43%), Gaps = 50/520 (9%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-----LEEMRHELDEERTAKLA-- 271
E L + L Q+ ++ ++E+ + + K +E + EL+ E++ K
Sbjct: 26 EELHHNIDDLLQEKKSLECEVEELHRTVQKRQRQKDFIDGNVESLMTELEIEKSLKHHED 85
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ---SRQKEVQLEAR 328
I +++ E L + R+ + + D+ L EAE+ ++ K ++ +++ +Q E+
Sbjct: 86 IVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESD 145
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ---QIEKLTVQHKSAIQQLEED---L 382
A +L + V + QQ SLQA+ + +Q + E++ + + + D L
Sbjct: 146 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 205
Query: 383 KQTKRALQEQCEITKREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
+ K L E+ + +++IE+ ER E LQ + + LQAK ELEK K +
Sbjct: 206 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEM 265
Query: 442 IDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQ--KLAAELLNKEEIIGKMQIQT 499
L +L KE L + + + K + + ++G + + + + ++ ++ Q
Sbjct: 266 AVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK 325
Query: 500 RELIKNIKLNEQKVI------QYEQYVRDLQAHNRTIANCQ-ESPNGISYQDLQQ-EIMD 551
EL N++++E+K + E+ +LQ R ++ + E N + L+ E+
Sbjct: 326 GEL--NVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELQNILDMLQLENHELQG 383
Query: 552 LKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRE 611
LK++ V E+ + ++ ELE + S+ Q I+ +++L+ K + + E
Sbjct: 384 LKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAE 443
Query: 612 LAALQ----------QDLEHRMRIVDEV---NKQIAAKADE--------IQELFATLENK 650
ALQ +DL+ + I ++ K++ A A+E +++L +
Sbjct: 444 SRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLDLNVRKL 503
Query: 651 QQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELA 690
QQ++ +L + L+L + +L+ ELA
Sbjct: 504 QQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELA 543
Score = 65.3 bits (152), Expect = 7e-10
Identities = 112/525 (21%), Positives = 240/525 (45%), Gaps = 65/525 (12%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
L + K + E+ + + + + + L E L E+ KL++D+E D ++
Sbjct: 177 LEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQV 236
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV---------AKMDKQ 296
ESE L+ R EL++ ++ + ++++ + QL + + AK D Q
Sbjct: 237 LKESE--VLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQ 294
Query: 297 --LREAEASITSLTGTVK----MLEDQSRQK-EVQLEARARK-----LRESLKTGE---- 340
LR E +T ++ +LE+ S QK E+ ++ RK +++ ++ E
Sbjct: 295 EALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQ 354
Query: 341 VTTSQLIQQRDSLQ--AEVLECK-QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
V Q+ + + LQ ++L+ + +++ L +QH + +LE K L+E+ E+
Sbjct: 355 VVLRQMSKHKTELQNILDMLQLENHELQGLKLQHDQRVSELE---KTQVAVLEEKLELEN 411
Query: 398 -REIELKERTETE-----LQDSRNAIEELQAKIIELEK-----SKPNPDLPTEREIDLW- 445
++I +++ E E L+ + IE + A+ L+ SK DL + + D+W
Sbjct: 412 LQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDL--QEKCDIWE 469
Query: 446 AELQATKETLRVTEDEVTTCKREKESENKIGIQ-QKLAAEL--LNKEEIIGKMQIQTREL 502
+L TK L E+ K E+ + K+ + +KL EL LN++++ I +
Sbjct: 470 KKLAQTKRVLAAAEE---NSKMEQSNLEKLDLNVRKLQQELDQLNRDKLSLHNDISAMQ- 525
Query: 503 IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQD-LQQEIMDLKMKLLDVVH 561
+ ++ + V ++ + ++Q H +A Q+ + +QD L E L+ + + +
Sbjct: 526 -QQLQEKREAVNSLQEELANVQDH-LNLAK-QDLLHTTKHQDVLLSEQTRLQKDISEWAN 582
Query: 562 RNEELSEILAKKDQELE-QQDKNSRGQARVIKIREELINVLKNKETEQSR----ELAALQ 616
R E+ + K Q+L+ Q++ + ++++ + K +E+E+S+ ++ +
Sbjct: 583 RFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKE 642
Query: 617 QDLEHRMRIVDEVNK--QIAAKADEIQELFATLENKQQQIHRLEK 659
Q + + D+ +K Q+ +K +E TL+ +++ LEK
Sbjct: 643 QQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEK 687
Score = 46.8 bits (106), Expect = 3e-04
Identities = 56/294 (19%), Positives = 135/294 (45%), Gaps = 15/294 (5%)
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIE--LKERTETELQDSRNAIEELQAKIIE 426
+QH + ++ E ++ +KR +++ E I+ L+E+ E + +EEL + +
Sbjct: 1 MQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECE-----VEELHRTVQK 55
Query: 427 LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELL 486
++ K D E L EL+ K +L+ ED V + +++ K + + A LL
Sbjct: 56 RQRQKDFIDGNVE---SLMTELEIEK-SLKHHEDIVDEIECIEKTLLKRRSELREADRLL 111
Query: 487 NKEEI-IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH-NRTIANCQESPNGISYQD 544
+ E + + +T+ ++ ++ ++Q E +L+ T N ++ + +
Sbjct: 112 AEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQL--RS 169
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK 604
LQ + DL+ + +E+++I+A KD + + K ++ ++ I + +
Sbjct: 170 LQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERN 229
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
E + L + L+ + ++++ Q+ ++ E+ L L +K++++H L+
Sbjct: 230 EDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ 283
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 74.5 bits (175), Expect = 1e-12
Identities = 116/504 (23%), Positives = 222/504 (44%), Gaps = 44/504 (8%)
Query: 188 ELKTQAE----DAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR 243
ELKTQ E D + + +L + ER EAL AKL + ++ + ++ IR
Sbjct: 398 ELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALR---AKLMKVIKEKENSLEAIR 454
Query: 244 EL--RSESENTKALEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLR 298
++E ++ +E+ ++L E K E+ + + +++T N++ + ++Q
Sbjct: 455 SKLDKAEDQHLVEMEDTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFN 514
Query: 299 EAEASITSLTGTVKMLEDQSRQK---EVQLEARARKLR----ESLKTGEVTTSQLIQQRD 351
+ + L + +E + R+K E QL KL E +K +SQL + D
Sbjct: 515 MLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND 574
Query: 352 SLQAEVLECKQQIEKLTVQHKSA--IQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
L+ + + ++ KLT +++A +Q+ ED+ T +A Q Q E K+ E K+ E +
Sbjct: 575 ELRLKERDVEELQLKLTKANENASFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKELERK 632
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREK 469
L D +E + EL+ T+ + + LQ ++TL TED++ + E
Sbjct: 633 LSDLEKKMETSHNQCQELKARYERATSETKTKHE--EILQNLQKTLLDTEDKLKGAREEN 690
Query: 470 ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRT 529
G+ Q+L E L K+ K QT E +++ EQ + + + L+ +T
Sbjct: 691 S-----GLLQEL--EELRKQAEKAK-AAQTAE--DAMQIMEQMTKEKTETLASLEDTKQT 740
Query: 530 IANCQESPNGISYQDLQQ-EIMDLKMKLLDVVHRNEE--LSEILAKKDQELEQQDKNSRG 586
A Q + + +L+ E ++ +LL V ++ E EI K ++ + S
Sbjct: 741 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 800
Query: 587 QARVIKIREEL----INVLKNKETEQSRELA--ALQQDLEHRMRIVDEVNKQIAAKADEI 640
Q +K+ EEL V +++ E+ R + L + + + + + +++ A+ I
Sbjct: 801 QEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSI 860
Query: 641 QELFATLENKQQQIHRLEKIVLAL 664
A L K ++ +L V L
Sbjct: 861 SITSALLTEKDAELEKLRNEVTVL 884
Score = 54.4 bits (125), Expect = 1e-06
Identities = 111/497 (22%), Positives = 212/497 (42%), Gaps = 51/497 (10%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR 243
G L E ++ ++ T L + A E++ I E L+ E R +V + EI
Sbjct: 85 GLLTETSSRYARKISGTTALQE-ALKEKQQHI---EQLLAERDLERAEVAKATSHVGEIE 140
Query: 244 E---LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+ L + + LE + ++D+ RT A + +QL + + +V D Q R
Sbjct: 141 QELALARDGHDQHVLE-LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVE--DLQFRVE 197
Query: 301 EASITSLTGTVKMLEDQSRQKEVQL-----EARARKLRESLKTGEVTT----SQLIQQRD 351
E SIT + + +R KE++ + +A KL+ L+ V T S++++
Sbjct: 198 EESITKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEK 257
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
L V E + +L + + L Q +LQE+ E+T+ + +R T L+
Sbjct: 258 DLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTD---HQREITSLK 314
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQ-ATKETLRVTEDEVTTCKREKE 470
+ A EE K I+ + L E E L ++L+ A KE D + K +
Sbjct: 315 EHFGAREETHQKEIKALYT-ATEKLSKENE-SLKSKLEHANKE----NSDVIALWK--SK 366
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
E I Q+ EL K + +T E + E+ + Y+ + +LQ
Sbjct: 367 LETAIASHQQAMEEL--KVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQ------ 418
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
N Q+S ++++ L+ KL+ V+ E E + K + E Q + +
Sbjct: 419 -NQQDSERAAHAKEMEA----LRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEM-EDTL 472
Query: 591 IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAKADEIQELFATL 647
K++E + K K E S E ++Q+ ++ + + + +Q +++ ++++E A +
Sbjct: 473 NKLQE--AEIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADM 530
Query: 648 ENK-QQQIHRLEKIVLA 663
E K +++ R E+++ A
Sbjct: 531 EAKFREKDEREEQLIKA 547
>AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain protein.
Length = 1995
Score = 74.1 bits (174), Expect = 1e-12
Identities = 100/488 (20%), Positives = 201/488 (41%), Gaps = 28/488 (5%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
R L ++ + + + +RA R L E L +A+ + R ++ +RE +
Sbjct: 1075 RRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQ 1134
Query: 247 SE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ +E + LE R + + + E+L +L T + + + E +T
Sbjct: 1135 AALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVT 1194
Query: 306 SLTGTVKMLEDQSRQKEVQL-EARAR------KLRESLKTGEVTTSQLIQQRDSLQAEVL 358
L K LE+++R E + E R R +L E L+ + R +L+AEV
Sbjct: 1195 ELK---KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVS 1251
Query: 359 ECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
E + ++ L + Q+ LE L++ + + E +R + EL++
Sbjct: 1252 ELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSG 1311
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL--RVTEDEVTTCKREKESEN 473
A+ E ++K I L K + + +L E K L RV E ++ E
Sbjct: 1312 ALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1371
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
+ +++ EL + + + + + E ++ E+ + R+ +A + +A
Sbjct: 1372 EAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEA---RRRAAREAEALTQRLAEK 1428
Query: 534 QESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
E+ + + + LQQE+ D M L + +L L KK ++ +Q + A V+
Sbjct: 1429 TETVDRLERGRRRLQQELDDATMDL----EQQRQLVSTLEKKQRKFDQLLAEEK--AAVL 1482
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ EE ++R L+ L + LE +E+ +Q A E++ L ++ ++
Sbjct: 1483 RAVEERERAEAEGREREARALS-LTRALEEEQEAREELERQNRALRAELEALLSSKDDVG 1541
Query: 652 QQIHRLEK 659
+ +H LE+
Sbjct: 1542 KSVHELER 1549
Score = 72.5 bits (170), Expect = 5e-12
Identities = 104/443 (23%), Positives = 186/443 (41%), Gaps = 42/443 (9%)
Query: 222 VREVAKLRQDVETRNVMID-EIRELRSES-ENTKALEEMRHEL---DEERTAKLAIKEKL 276
+R+ K RQ++E +D E EL+ + E + EE+R +L +EE A LA E
Sbjct: 1060 LRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDE 1119
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
+QL ++ + + L EA+ + S E Q R +LEA +L ++L
Sbjct: 1120 GGARAQLLKS---LREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1176
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
+ T+ + R + EV E K+ +E+ T H++A+Q+L + Q L EQ E
Sbjct: 1177 DS----TNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQA 1232
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+R E+T L+ + EL+A++ L+ ++ + R ELQ + R
Sbjct: 1233 RRGKGAWEKTRLALEAE---VSELRAELSSLQTARQEGEQRRRR-----LELQLQEVQGR 1284
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+ E + E+ K+ Q+ AEL N + + + +T L K + E ++
Sbjct: 1285 AGDGE----RARAEAAEKL---QRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDA 1337
Query: 517 EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQE 576
++ LQ R + G + ++ E L+ +L + E L +
Sbjct: 1338 QEL---LQEETRA-----KLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQ 1389
Query: 577 LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAK 636
L + + +A ++ EE +RE AL Q L + VD + +
Sbjct: 1390 LSEWRRRQEEEAGALEAGEE-------ARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1442
Query: 637 ADEIQELFATLENKQQQIHRLEK 659
E+ + LE ++Q + LEK
Sbjct: 1443 QQELDDATMDLEQQRQLVSTLEK 1465
Score = 69.3 bits (162), Expect = 4e-11
Identities = 116/507 (22%), Positives = 215/507 (42%), Gaps = 48/507 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS 247
+L + + AV + +RA E R A +L R L ++ E R + + R LR+
Sbjct: 1472 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA---LEEEQEAREELERQNRALRA 1528
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
E LE + D+ + ++ E R +V +++ +L AE + L
Sbjct: 1529 E------LEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRL 1582
Query: 308 TGTVKMLEDQSRQ----KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
TV+ L+ Q + ++ E R R+L + L+ EV + +QR A + + +
Sbjct: 1583 EVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGE 1642
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
+E+L Q SA Q EE +KQ R +Q Q + RE+E + RT E S+N E + K
Sbjct: 1643 LEELKAQMASAGQGKEEAVKQL-RKMQAQMKELWREVE-ETRTSREEIFSQNRESEKRLK 1700
Query: 424 IIELEKSKPNPDLPTEREIDLWAEL---QATKETLRVTEDEVTTCKREKESENKIG-IQQ 479
+E E + +L A+ + E + + +++ E ++G +++
Sbjct: 1701 GLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEE 1760
Query: 480 KLAAELLNKE---EIIGKMQIQTRELIKNIKLN-------EQKVIQYEQYVRDLQA---- 525
+L E N E + K+ +Q L + E Q E+ +++L+
Sbjct: 1761 ELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGE 1820
Query: 526 --------HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL 577
H TIA ES + + L+QE + + V + L E++ + ++E
Sbjct: 1821 EDAGARARHKMTIA-ALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1879
Query: 578 EQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAA---LQQDLEHRMRIVDEVNKQI 633
D+ R Q +R ++L L+ E E SR A LQ++LE + +N+++
Sbjct: 1880 RVADQ-LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREV 1938
Query: 634 AAKADEIQELFATLENKQ-QQIHRLEK 659
+ ++ T + +Q+ RLE+
Sbjct: 1939 TTLRNRLRRGPLTFTTRTVRQVFRLEE 1965
Score = 55.2 bits (127), Expect = 7e-07
Identities = 93/437 (21%), Positives = 180/437 (41%), Gaps = 38/437 (8%)
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
LR N A ++RH K+ ++T + L+ + K+ + +++ +
Sbjct: 833 LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV 892
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT-GEVTTSQ-----LIQQRDSLQAEVL 358
L G V LE++ + QL A A E+ +T G + + ++ + ++ E
Sbjct: 893 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE 952
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE-QCEITKREIELKERTE--TELQDSRN 415
EC +Q++ + + IQ+LE L+ + A Q+ Q E E ++K+ E L+D +
Sbjct: 953 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1012
Query: 416 AIEELQA--KIIELEKSKPNPDLPTERE-------IDLWAELQATKETLRVTE---DEVT 463
+ + + KI+ S P R ++ + Q ++ LR E E+
Sbjct: 1013 KLSKSGSCWKIV-WPSSHPRQLRRRRRSRASISYGSNMRPQSQTWRDRLRKEEKGRQELE 1071
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
KR + E+ +Q+++ + EE+ ++ + EL + E + Q ++ L
Sbjct: 1072 KLKRRLDGESS-ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSL 1130
Query: 524 QAHNRTIANCQESPNG---------ISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKD 574
+ +A QE +DL +E+ L+ +L D + E+ +K++
Sbjct: 1131 REAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKRE 1190
Query: 575 QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA 634
QE+ + K + R I E + L+ + + ELA + LE R K
Sbjct: 1191 QEVTELKKTLEEETR---IHEAAVQELRQRHGQALGELA---EQLEQARRGKGAWEKTRL 1244
Query: 635 AKADEIQELFATLENKQ 651
A E+ EL A L + Q
Sbjct: 1245 ALEAEVSELRAELSSLQ 1261
Score = 53.6 bits (123), Expect = 2e-06
Identities = 104/475 (21%), Positives = 203/475 (42%), Gaps = 49/475 (10%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E L+ + + E+ + + + + L + EA + + +L Q+ ETR +
Sbjct: 1294 EAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST-EAQLHDAQELLQE-ETRAKLAL 1351
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
R E+E +R +L+EE A+ +L T ++QL + R R +E
Sbjct: 1352 GSRVRAMEAEAAG----LREQLEEEAAARERAGRELQTAQAQLSEWRRR--------QEE 1399
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDSLQAEV 357
EA G ++ E+ R+ + EA ++L E +T E +L Q+ D ++
Sbjct: 1400 EA------GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1453
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ +Q + L + + Q L E+ RA++E+ + E E +ER L +R A+
Sbjct: 1454 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER---ERAEAEGREREARALSLTR-AL 1509
Query: 418 EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGI 477
EE Q ELE+ N L E E A L + + + + C+ +++ N +
Sbjct: 1510 EEEQEAREELERQ--NRALRAELE----ALLSSKDDVGKSVHELERACRVAEQAANDLRA 1563
Query: 478 Q-QKLAAELLNKEEIIGKMQI--------QTRELIKNIKLNEQKVIQYEQYVRDLQAHNR 528
Q +L EL E+ ++++ R+L + E++ Q + +RD + R
Sbjct: 1564 QVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV-ER 1622
Query: 529 TIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQA 588
Q + + + L+ E+ +LK ++ EE + L K ++++ + +
Sbjct: 1623 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE-ET 1681
Query: 589 RVIKIREELINVLKNKETEQS-RELAALQQDLEHRMRIVDEVNKQIAAKADEIQE 642
R REE+ + +N+E+E+ + L A L+ + D +Q DE+ +
Sbjct: 1682 RT--SREEIFS--QNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD 1732
>AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 74.1 bits (174), Expect = 1e-12
Identities = 83/354 (23%), Positives = 164/354 (46%), Gaps = 21/354 (5%)
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQ--RDSLQAEVLECKQQIEKLTVQHKSAIQ 376
R ++ +LE +RKL+ES +T + + S E+ K++IEKL Q +
Sbjct: 450 RLEQEKLEL-SRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTES-S 507
Query: 377 QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI--EELQAKIIELEKSKPNP 434
LE+ L++ A++++ + R+I+ E+ LQ R + E +QA +SK
Sbjct: 508 HLEQQLEEAN-AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELK 566
Query: 435 DLPTEREIDL--WAELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELLNKEE 490
D +R++ + + E+ L + ++ R+KE E + +Q + L EL E
Sbjct: 567 DAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTER 626
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GISYQDLQQEI 549
++++ T L + + Q E Y + L+ + Q S + G+ + QQEI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 550 MDLKMKL-LDVVHRNEELSE---ILAKKDQELEQQDKNSRGQA-----RVIKIREELINV 600
LK L + EELS+ I A + + L+++ +S GQ ++ ++++L
Sbjct: 687 TKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKT 746
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++E+ + +Q E ++ E NK++ ++ D++ L+ L QQ+
Sbjct: 747 RRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQL 800
Score = 56.8 bits (131), Expect = 2e-07
Identities = 92/458 (20%), Positives = 203/458 (44%), Gaps = 33/458 (7%)
Query: 202 DLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+LS++ +T+ A+ + V +D+E +N+ +EI +LR + + LE+ E
Sbjct: 457 ELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLK-EEIEKLRKQVTESSHLEQQLEE 515
Query: 262 LDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQK 321
+ R ++ E Q++ + ++K+L +A + + + K L+D Q+
Sbjct: 516 ANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS---KELKDAHCQR 572
Query: 322 EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++ ++ ++ E L +L + + EV Q++E L Q ++ +++
Sbjct: 573 KLAMQ-EFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLR-QELRRTERAKKE 630
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK----IIELEKSKPNPDLP 437
L+ AL + ++ E E +L++ +++ Q + +E + L
Sbjct: 631 LEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLK 690
Query: 438 TERE-IDLWAELQATKETLRVTEDEVTTCKRE-KESE-NKIGIQQKLAAELLNKEEIIGK 494
T+ E ++ E + +K + +E+ K+E +SE ++ + +++ E+ +
Sbjct: 691 TDLEKKSIFYEEELSKRE-GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 749
Query: 495 MQIQTRELIKNIK--LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
Q + E K +KV+ E+ + L + + E+ + I Q L++E+ DL
Sbjct: 750 SQSEREEFESEFKQQYEREKVLLTEEN-KKLTSELDKLTTLYENLS-IHNQQLEEEVKDL 807
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG--QARVIKIREELINVLKN-----KE 605
K V H +++EI+ + +K++RG QA K+ EEL L+N +
Sbjct: 808 ADKKESVAHWEAQITEII-----QWVSDEKDARGYLQALASKMTEEL-EALRNSSLGTRA 861
Query: 606 TEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQE 642
T+ ++ + D+ R+ + ++ +I AK IQE
Sbjct: 862 TDMPWKMRRFAKLDMSARLELQSALDAEIRAK-QAIQE 898
Score = 53.2 bits (122), Expect = 3e-06
Identities = 90/414 (21%), Positives = 184/414 (44%), Gaps = 29/414 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA-EASITSLT 308
+N A E + KL + KL + ++ + + +D L + + I +L
Sbjct: 436 DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQ--YSTVDGPLTASKDLEIKNLK 493
Query: 309 GTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ L Q S E QLE A +R+ L +Q +LQ E + +++
Sbjct: 494 EEIEKLRKQVTESSHLEQQLE-EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELV 552
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIEELQA 422
+ + + K+ ++L++ Q K A+QE EI +R EL K++ ++D ++ +
Sbjct: 553 QASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ 612
Query: 423 KIIELEKSKPNPDLPTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ L + + ++E+++ E L A R ++ ++ E+E + G++QK
Sbjct: 613 KVESLRQELRRTE-RAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELE-GLKQKQ 670
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQYVRDLQA-HNRTIANCQESPNG 539
+ G I+ ++ I +K + E+K I YE+ + + H I N ++ +
Sbjct: 671 IS------YSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHD 724
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
Q L +EIM LK KL R E SE +++ E E + + R + + + ++L
Sbjct: 725 SEGQQLALNKEIMILKDKLEKT--RRESQSE---REEFESEFKQQYEREKVLLTEENKKL 779
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ L +K T L+ Q LE ++ + + + +A +I E+ + +++
Sbjct: 780 TSEL-DKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEK 832
>AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 74.1 bits (174), Expect = 1e-12
Identities = 83/354 (23%), Positives = 164/354 (46%), Gaps = 21/354 (5%)
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQ--RDSLQAEVLECKQQIEKLTVQHKSAIQ 376
R ++ +LE +RKL+ES +T + + S E+ K++IEKL Q +
Sbjct: 450 RLEQEKLEL-SRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTES-S 507
Query: 377 QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI--EELQAKIIELEKSKPNP 434
LE+ L++ A++++ + R+I+ E+ LQ R + E +QA +SK
Sbjct: 508 HLEQQLEEAN-AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELK 566
Query: 435 DLPTEREIDL--WAELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELLNKEE 490
D +R++ + + E+ L + ++ R+KE E + +Q + L EL E
Sbjct: 567 DAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTER 626
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GISYQDLQQEI 549
++++ T L + + Q E Y + L+ + Q S + G+ + QQEI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 550 MDLKMKL-LDVVHRNEELSE---ILAKKDQELEQQDKNSRGQA-----RVIKIREELINV 600
LK L + EELS+ I A + + L+++ +S GQ ++ ++++L
Sbjct: 687 TKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKT 746
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++E+ + +Q E ++ E NK++ ++ D++ L+ L QQ+
Sbjct: 747 RRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQL 800
Score = 56.8 bits (131), Expect = 2e-07
Identities = 92/458 (20%), Positives = 203/458 (44%), Gaps = 33/458 (7%)
Query: 202 DLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+LS++ +T+ A+ + V +D+E +N+ +EI +LR + + LE+ E
Sbjct: 457 ELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLK-EEIEKLRKQVTESSHLEQQLEE 515
Query: 262 LDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQK 321
+ R ++ E Q++ + ++K+L +A + + + K L+D Q+
Sbjct: 516 ANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS---KELKDAHCQR 572
Query: 322 EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++ ++ ++ E L +L + + EV Q++E L Q ++ +++
Sbjct: 573 KLAMQ-EFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLR-QELRRTERAKKE 630
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK----IIELEKSKPNPDLP 437
L+ AL + ++ E E +L++ +++ Q + +E + L
Sbjct: 631 LEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLK 690
Query: 438 TERE-IDLWAELQATKETLRVTEDEVTTCKRE-KESE-NKIGIQQKLAAELLNKEEIIGK 494
T+ E ++ E + +K + +E+ K+E +SE ++ + +++ E+ +
Sbjct: 691 TDLEKKSIFYEEELSKRE-GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 749
Query: 495 MQIQTRELIKNIK--LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
Q + E K +KV+ E+ + L + + E+ + I Q L++E+ DL
Sbjct: 750 SQSEREEFESEFKQQYEREKVLLTEEN-KKLTSELDKLTTLYENLS-IHNQQLEEEVKDL 807
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG--QARVIKIREELINVLKN-----KE 605
K V H +++EI+ + +K++RG QA K+ EEL L+N +
Sbjct: 808 ADKKESVAHWEAQITEII-----QWVSDEKDARGYLQALASKMTEEL-EALRNSSLGTRA 861
Query: 606 TEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQE 642
T+ ++ + D+ R+ + ++ +I AK IQE
Sbjct: 862 TDMPWKMRRFAKLDMSARLELQSALDAEIRAK-QAIQE 898
Score = 53.2 bits (122), Expect = 3e-06
Identities = 90/414 (21%), Positives = 184/414 (44%), Gaps = 29/414 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA-EASITSLT 308
+N A E + KL + KL + ++ + + +D L + + I +L
Sbjct: 436 DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQ--YSTVDGPLTASKDLEIKNLK 493
Query: 309 GTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ L Q S E QLE A +R+ L +Q +LQ E + +++
Sbjct: 494 EEIEKLRKQVTESSHLEQQLE-EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELV 552
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIEELQA 422
+ + + K+ ++L++ Q K A+QE EI +R EL K++ ++D ++ +
Sbjct: 553 QASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ 612
Query: 423 KIIELEKSKPNPDLPTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ L + + ++E+++ E L A R ++ ++ E+E + G++QK
Sbjct: 613 KVESLRQELRRTE-RAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELE-GLKQKQ 670
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQYVRDLQA-HNRTIANCQESPNG 539
+ G I+ ++ I +K + E+K I YE+ + + H I N ++ +
Sbjct: 671 IS------YSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHD 724
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
Q L +EIM LK KL R E SE +++ E E + + R + + + ++L
Sbjct: 725 SEGQQLALNKEIMILKDKLEKT--RRESQSE---REEFESEFKQQYEREKVLLTEENKKL 779
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ L +K T L+ Q LE ++ + + + +A +I E+ + +++
Sbjct: 780 TSEL-DKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEK 832
>AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 74.1 bits (174), Expect = 1e-12
Identities = 83/354 (23%), Positives = 164/354 (46%), Gaps = 21/354 (5%)
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQ--RDSLQAEVLECKQQIEKLTVQHKSAIQ 376
R ++ +LE +RKL+ES +T + + S E+ K++IEKL Q +
Sbjct: 450 RLEQEKLEL-SRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTES-S 507
Query: 377 QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI--EELQAKIIELEKSKPNP 434
LE+ L++ A++++ + R+I+ E+ LQ R + E +QA +SK
Sbjct: 508 HLEQQLEEAN-AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELK 566
Query: 435 DLPTEREIDL--WAELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELLNKEE 490
D +R++ + + E+ L + ++ R+KE E + +Q + L EL E
Sbjct: 567 DAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTER 626
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GISYQDLQQEI 549
++++ T L + + Q E Y + L+ + Q S + G+ + QQEI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 550 MDLKMKL-LDVVHRNEELSE---ILAKKDQELEQQDKNSRGQA-----RVIKIREELINV 600
LK L + EELS+ I A + + L+++ +S GQ ++ ++++L
Sbjct: 687 TKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKT 746
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++E+ + +Q E ++ E NK++ ++ D++ L+ L QQ+
Sbjct: 747 RRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQL 800
Score = 56.8 bits (131), Expect = 2e-07
Identities = 92/458 (20%), Positives = 203/458 (44%), Gaps = 33/458 (7%)
Query: 202 DLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+LS++ +T+ A+ + V +D+E +N+ +EI +LR + + LE+ E
Sbjct: 457 ELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLK-EEIEKLRKQVTESSHLEQQLEE 515
Query: 262 LDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQK 321
+ R ++ E Q++ + ++K+L +A + + + K L+D Q+
Sbjct: 516 ANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS---KELKDAHCQR 572
Query: 322 EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++ ++ ++ E L +L + + EV Q++E L Q ++ +++
Sbjct: 573 KLAMQ-EFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLR-QELRRTERAKKE 630
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK----IIELEKSKPNPDLP 437
L+ AL + ++ E E +L++ +++ Q + +E + L
Sbjct: 631 LEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLK 690
Query: 438 TERE-IDLWAELQATKETLRVTEDEVTTCKRE-KESE-NKIGIQQKLAAELLNKEEIIGK 494
T+ E ++ E + +K + +E+ K+E +SE ++ + +++ E+ +
Sbjct: 691 TDLEKKSIFYEEELSKRE-GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 749
Query: 495 MQIQTRELIKNIK--LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
Q + E K +KV+ E+ + L + + E+ + I Q L++E+ DL
Sbjct: 750 SQSEREEFESEFKQQYEREKVLLTEEN-KKLTSELDKLTTLYENLS-IHNQQLEEEVKDL 807
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG--QARVIKIREELINVLKN-----KE 605
K V H +++EI+ + +K++RG QA K+ EEL L+N +
Sbjct: 808 ADKKESVAHWEAQITEII-----QWVSDEKDARGYLQALASKMTEEL-EALRNSSLGTRA 861
Query: 606 TEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQE 642
T+ ++ + D+ R+ + ++ +I AK IQE
Sbjct: 862 TDMPWKMRRFAKLDMSARLELQSALDAEIRAK-QAIQE 898
Score = 53.2 bits (122), Expect = 3e-06
Identities = 90/414 (21%), Positives = 184/414 (44%), Gaps = 29/414 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA-EASITSLT 308
+N A E + KL + KL + ++ + + +D L + + I +L
Sbjct: 436 DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQ--YSTVDGPLTASKDLEIKNLK 493
Query: 309 GTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ L Q S E QLE A +R+ L +Q +LQ E + +++
Sbjct: 494 EEIEKLRKQVTESSHLEQQLE-EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELV 552
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIEELQA 422
+ + + K+ ++L++ Q K A+QE EI +R EL K++ ++D ++ +
Sbjct: 553 QASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ 612
Query: 423 KIIELEKSKPNPDLPTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ L + + ++E+++ E L A R ++ ++ E+E + G++QK
Sbjct: 613 KVESLRQELRRTE-RAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELE-GLKQKQ 670
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQYVRDLQA-HNRTIANCQESPNG 539
+ G I+ ++ I +K + E+K I YE+ + + H I N ++ +
Sbjct: 671 IS------YSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHD 724
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
Q L +EIM LK KL R E SE +++ E E + + R + + + ++L
Sbjct: 725 SEGQQLALNKEIMILKDKLEKT--RRESQSE---REEFESEFKQQYEREKVLLTEENKKL 779
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ L +K T L+ Q LE ++ + + + +A +I E+ + +++
Sbjct: 780 TSEL-DKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEK 832
>AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 74.1 bits (174), Expect = 1e-12
Identities = 83/354 (23%), Positives = 164/354 (46%), Gaps = 21/354 (5%)
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQ--RDSLQAEVLECKQQIEKLTVQHKSAIQ 376
R ++ +LE +RKL+ES +T + + S E+ K++IEKL Q +
Sbjct: 450 RLEQEKLEL-SRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTES-S 507
Query: 377 QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI--EELQAKIIELEKSKPNP 434
LE+ L++ A++++ + R+I+ E+ LQ R + E +QA +SK
Sbjct: 508 HLEQQLEEAN-AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELK 566
Query: 435 DLPTEREIDL--WAELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELLNKEE 490
D +R++ + + E+ L + ++ R+KE E + +Q + L EL E
Sbjct: 567 DAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTER 626
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GISYQDLQQEI 549
++++ T L + + Q E Y + L+ + Q S + G+ + QQEI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 550 MDLKMKL-LDVVHRNEELSE---ILAKKDQELEQQDKNSRGQA-----RVIKIREELINV 600
LK L + EELS+ I A + + L+++ +S GQ ++ ++++L
Sbjct: 687 TKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKT 746
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++E+ + +Q E ++ E NK++ ++ D++ L+ L QQ+
Sbjct: 747 RRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQL 800
Score = 56.8 bits (131), Expect = 2e-07
Identities = 92/458 (20%), Positives = 203/458 (44%), Gaps = 33/458 (7%)
Query: 202 DLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+LS++ +T+ A+ + V +D+E +N+ +EI +LR + + LE+ E
Sbjct: 457 ELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLK-EEIEKLRKQVTESSHLEQQLEE 515
Query: 262 LDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQK 321
+ R ++ E Q++ + ++K+L +A + + + K L+D Q+
Sbjct: 516 ANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS---KELKDAHCQR 572
Query: 322 EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++ ++ ++ E L +L + + EV Q++E L Q ++ +++
Sbjct: 573 KLAMQ-EFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLR-QELRRTERAKKE 630
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK----IIELEKSKPNPDLP 437
L+ AL + ++ E E +L++ +++ Q + +E + L
Sbjct: 631 LEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLK 690
Query: 438 TERE-IDLWAELQATKETLRVTEDEVTTCKRE-KESE-NKIGIQQKLAAELLNKEEIIGK 494
T+ E ++ E + +K + +E+ K+E +SE ++ + +++ E+ +
Sbjct: 691 TDLEKKSIFYEEELSKRE-GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 749
Query: 495 MQIQTRELIKNIK--LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
Q + E K +KV+ E+ + L + + E+ + I Q L++E+ DL
Sbjct: 750 SQSEREEFESEFKQQYEREKVLLTEEN-KKLTSELDKLTTLYENLS-IHNQQLEEEVKDL 807
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG--QARVIKIREELINVLKN-----KE 605
K V H +++EI+ + +K++RG QA K+ EEL L+N +
Sbjct: 808 ADKKESVAHWEAQITEII-----QWVSDEKDARGYLQALASKMTEEL-EALRNSSLGTRA 861
Query: 606 TEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQE 642
T+ ++ + D+ R+ + ++ +I AK IQE
Sbjct: 862 TDMPWKMRRFAKLDMSARLELQSALDAEIRAK-QAIQE 898
Score = 53.2 bits (122), Expect = 3e-06
Identities = 90/414 (21%), Positives = 184/414 (44%), Gaps = 29/414 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA-EASITSLT 308
+N A E + KL + KL + ++ + + +D L + + I +L
Sbjct: 436 DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQ--YSTVDGPLTASKDLEIKNLK 493
Query: 309 GTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ L Q S E QLE A +R+ L +Q +LQ E + +++
Sbjct: 494 EEIEKLRKQVTESSHLEQQLE-EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELV 552
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIEELQA 422
+ + + K+ ++L++ Q K A+QE EI +R EL K++ ++D ++ +
Sbjct: 553 QASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ 612
Query: 423 KIIELEKSKPNPDLPTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ L + + ++E+++ E L A R ++ ++ E+E + G++QK
Sbjct: 613 KVESLRQELRRTE-RAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELE-GLKQKQ 670
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQYVRDLQA-HNRTIANCQESPNG 539
+ G I+ ++ I +K + E+K I YE+ + + H I N ++ +
Sbjct: 671 IS------YSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHD 724
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
Q L +EIM LK KL R E SE +++ E E + + R + + + ++L
Sbjct: 725 SEGQQLALNKEIMILKDKLEKT--RRESQSE---REEFESEFKQQYEREKVLLTEENKKL 779
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ L +K T L+ Q LE ++ + + + +A +I E+ + +++
Sbjct: 780 TSEL-DKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEK 832
>AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 74.1 bits (174), Expect = 1e-12
Identities = 83/354 (23%), Positives = 164/354 (46%), Gaps = 21/354 (5%)
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQ--RDSLQAEVLECKQQIEKLTVQHKSAIQ 376
R ++ +LE +RKL+ES +T + + S E+ K++IEKL Q +
Sbjct: 450 RLEQEKLEL-SRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTES-S 507
Query: 377 QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI--EELQAKIIELEKSKPNP 434
LE+ L++ A++++ + R+I+ E+ LQ R + E +QA +SK
Sbjct: 508 HLEQQLEEAN-AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELK 566
Query: 435 DLPTEREIDL--WAELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELLNKEE 490
D +R++ + + E+ L + ++ R+KE E + +Q + L EL E
Sbjct: 567 DAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTER 626
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GISYQDLQQEI 549
++++ T L + + Q E Y + L+ + Q S + G+ + QQEI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 550 MDLKMKL-LDVVHRNEELSE---ILAKKDQELEQQDKNSRGQA-----RVIKIREELINV 600
LK L + EELS+ I A + + L+++ +S GQ ++ ++++L
Sbjct: 687 TKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKT 746
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++E+ + +Q E ++ E NK++ ++ D++ L+ L QQ+
Sbjct: 747 RRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQL 800
Score = 56.8 bits (131), Expect = 2e-07
Identities = 92/458 (20%), Positives = 203/458 (44%), Gaps = 33/458 (7%)
Query: 202 DLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+LS++ +T+ A+ + V +D+E +N+ +EI +LR + + LE+ E
Sbjct: 457 ELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLK-EEIEKLRKQVTESSHLEQQLEE 515
Query: 262 LDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQK 321
+ R ++ E Q++ + ++K+L +A + + + K L+D Q+
Sbjct: 516 ANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS---KELKDAHCQR 572
Query: 322 EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++ ++ ++ E L +L + + EV Q++E L Q ++ +++
Sbjct: 573 KLAMQ-EFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLR-QELRRTERAKKE 630
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK----IIELEKSKPNPDLP 437
L+ AL + ++ E E +L++ +++ Q + +E + L
Sbjct: 631 LEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLK 690
Query: 438 TERE-IDLWAELQATKETLRVTEDEVTTCKRE-KESE-NKIGIQQKLAAELLNKEEIIGK 494
T+ E ++ E + +K + +E+ K+E +SE ++ + +++ E+ +
Sbjct: 691 TDLEKKSIFYEEELSKRE-GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 749
Query: 495 MQIQTRELIKNIK--LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
Q + E K +KV+ E+ + L + + E+ + I Q L++E+ DL
Sbjct: 750 SQSEREEFESEFKQQYEREKVLLTEEN-KKLTSELDKLTTLYENLS-IHNQQLEEEVKDL 807
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG--QARVIKIREELINVLKN-----KE 605
K V H +++EI+ + +K++RG QA K+ EEL L+N +
Sbjct: 808 ADKKESVAHWEAQITEII-----QWVSDEKDARGYLQALASKMTEEL-EALRNSSLGTRA 861
Query: 606 TEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQE 642
T+ ++ + D+ R+ + ++ +I AK IQE
Sbjct: 862 TDMPWKMRRFAKLDMSARLELQSALDAEIRAK-QAIQE 898
Score = 53.2 bits (122), Expect = 3e-06
Identities = 90/414 (21%), Positives = 184/414 (44%), Gaps = 29/414 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA-EASITSLT 308
+N A E + KL + KL + ++ + + +D L + + I +L
Sbjct: 436 DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQ--YSTVDGPLTASKDLEIKNLK 493
Query: 309 GTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ L Q S E QLE A +R+ L +Q +LQ E + +++
Sbjct: 494 EEIEKLRKQVTESSHLEQQLE-EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELV 552
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIEELQA 422
+ + + K+ ++L++ Q K A+QE EI +R EL K++ ++D ++ +
Sbjct: 553 QASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ 612
Query: 423 KIIELEKSKPNPDLPTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ L + + ++E+++ E L A R ++ ++ E+E + G++QK
Sbjct: 613 KVESLRQELRRTE-RAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELE-GLKQKQ 670
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQYVRDLQA-HNRTIANCQESPNG 539
+ G I+ ++ I +K + E+K I YE+ + + H I N ++ +
Sbjct: 671 IS------YSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHD 724
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
Q L +EIM LK KL R E SE +++ E E + + R + + + ++L
Sbjct: 725 SEGQQLALNKEIMILKDKLEKT--RRESQSE---REEFESEFKQQYEREKVLLTEENKKL 779
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ L +K T L+ Q LE ++ + + + +A +I E+ + +++
Sbjct: 780 TSEL-DKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEK 832
>AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 74.1 bits (174), Expect = 1e-12
Identities = 83/354 (23%), Positives = 164/354 (46%), Gaps = 21/354 (5%)
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQ--RDSLQAEVLECKQQIEKLTVQHKSAIQ 376
R ++ +LE +RKL+ES +T + + S E+ K++IEKL Q +
Sbjct: 450 RLEQEKLEL-SRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTES-S 507
Query: 377 QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI--EELQAKIIELEKSKPNP 434
LE+ L++ A++++ + R+I+ E+ LQ R + E +QA +SK
Sbjct: 508 HLEQQLEEAN-AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELK 566
Query: 435 DLPTEREIDL--WAELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELLNKEE 490
D +R++ + + E+ L + ++ R+KE E + +Q + L EL E
Sbjct: 567 DAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTER 626
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GISYQDLQQEI 549
++++ T L + + Q E Y + L+ + Q S + G+ + QQEI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 550 MDLKMKL-LDVVHRNEELSE---ILAKKDQELEQQDKNSRGQA-----RVIKIREELINV 600
LK L + EELS+ I A + + L+++ +S GQ ++ ++++L
Sbjct: 687 TKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKT 746
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++E+ + +Q E ++ E NK++ ++ D++ L+ L QQ+
Sbjct: 747 RRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQL 800
Score = 56.8 bits (131), Expect = 2e-07
Identities = 92/458 (20%), Positives = 203/458 (44%), Gaps = 33/458 (7%)
Query: 202 DLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+LS++ +T+ A+ + V +D+E +N+ +EI +LR + + LE+ E
Sbjct: 457 ELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLK-EEIEKLRKQVTESSHLEQQLEE 515
Query: 262 LDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQK 321
+ R ++ E Q++ + ++K+L +A + + + K L+D Q+
Sbjct: 516 ANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS---KELKDAHCQR 572
Query: 322 EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++ ++ ++ E L +L + + EV Q++E L Q ++ +++
Sbjct: 573 KLAMQ-EFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLR-QELRRTERAKKE 630
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK----IIELEKSKPNPDLP 437
L+ AL + ++ E E +L++ +++ Q + +E + L
Sbjct: 631 LEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLK 690
Query: 438 TERE-IDLWAELQATKETLRVTEDEVTTCKRE-KESE-NKIGIQQKLAAELLNKEEIIGK 494
T+ E ++ E + +K + +E+ K+E +SE ++ + +++ E+ +
Sbjct: 691 TDLEKKSIFYEEELSKRE-GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 749
Query: 495 MQIQTRELIKNIK--LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
Q + E K +KV+ E+ + L + + E+ + I Q L++E+ DL
Sbjct: 750 SQSEREEFESEFKQQYEREKVLLTEEN-KKLTSELDKLTTLYENLS-IHNQQLEEEVKDL 807
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG--QARVIKIREELINVLKN-----KE 605
K V H +++EI+ + +K++RG QA K+ EEL L+N +
Sbjct: 808 ADKKESVAHWEAQITEII-----QWVSDEKDARGYLQALASKMTEEL-EALRNSSLGTRA 861
Query: 606 TEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQE 642
T+ ++ + D+ R+ + ++ +I AK IQE
Sbjct: 862 TDMPWKMRRFAKLDMSARLELQSALDAEIRAK-QAIQE 898
Score = 53.2 bits (122), Expect = 3e-06
Identities = 90/414 (21%), Positives = 184/414 (44%), Gaps = 29/414 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA-EASITSLT 308
+N A E + KL + KL + ++ + + +D L + + I +L
Sbjct: 436 DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQ--YSTVDGPLTASKDLEIKNLK 493
Query: 309 GTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ L Q S E QLE A +R+ L +Q +LQ E + +++
Sbjct: 494 EEIEKLRKQVTESSHLEQQLE-EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELV 552
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIEELQA 422
+ + + K+ ++L++ Q K A+QE EI +R EL K++ ++D ++ +
Sbjct: 553 QASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ 612
Query: 423 KIIELEKSKPNPDLPTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ L + + ++E+++ E L A R ++ ++ E+E + G++QK
Sbjct: 613 KVESLRQELRRTE-RAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELE-GLKQKQ 670
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQYVRDLQA-HNRTIANCQESPNG 539
+ G I+ ++ I +K + E+K I YE+ + + H I N ++ +
Sbjct: 671 IS------YSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHD 724
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
Q L +EIM LK KL R E SE +++ E E + + R + + + ++L
Sbjct: 725 SEGQQLALNKEIMILKDKLEKT--RRESQSE---REEFESEFKQQYEREKVLLTEENKKL 779
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ L +K T L+ Q LE ++ + + + +A +I E+ + +++
Sbjct: 780 TSEL-DKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEK 832
>AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 74.1 bits (174), Expect = 1e-12
Identities = 83/354 (23%), Positives = 164/354 (46%), Gaps = 21/354 (5%)
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQ--RDSLQAEVLECKQQIEKLTVQHKSAIQ 376
R ++ +LE +RKL+ES +T + + S E+ K++IEKL Q +
Sbjct: 450 RLEQEKLEL-SRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTES-S 507
Query: 377 QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI--EELQAKIIELEKSKPNP 434
LE+ L++ A++++ + R+I+ E+ LQ R + E +QA +SK
Sbjct: 508 HLEQQLEEAN-AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELK 566
Query: 435 DLPTEREIDL--WAELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELLNKEE 490
D +R++ + + E+ L + ++ R+KE E + +Q + L EL E
Sbjct: 567 DAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTER 626
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GISYQDLQQEI 549
++++ T L + + Q E Y + L+ + Q S + G+ + QQEI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 550 MDLKMKL-LDVVHRNEELSE---ILAKKDQELEQQDKNSRGQA-----RVIKIREELINV 600
LK L + EELS+ I A + + L+++ +S GQ ++ ++++L
Sbjct: 687 TKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKT 746
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++E+ + +Q E ++ E NK++ ++ D++ L+ L QQ+
Sbjct: 747 RRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQL 800
Score = 56.8 bits (131), Expect = 2e-07
Identities = 92/458 (20%), Positives = 203/458 (44%), Gaps = 33/458 (7%)
Query: 202 DLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+LS++ +T+ A+ + V +D+E +N+ +EI +LR + + LE+ E
Sbjct: 457 ELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLK-EEIEKLRKQVTESSHLEQQLEE 515
Query: 262 LDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQK 321
+ R ++ E Q++ + ++K+L +A + + + K L+D Q+
Sbjct: 516 ANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS---KELKDAHCQR 572
Query: 322 EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++ ++ ++ E L +L + + EV Q++E L Q ++ +++
Sbjct: 573 KLAMQ-EFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLR-QELRRTERAKKE 630
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK----IIELEKSKPNPDLP 437
L+ AL + ++ E E +L++ +++ Q + +E + L
Sbjct: 631 LEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLK 690
Query: 438 TERE-IDLWAELQATKETLRVTEDEVTTCKRE-KESE-NKIGIQQKLAAELLNKEEIIGK 494
T+ E ++ E + +K + +E+ K+E +SE ++ + +++ E+ +
Sbjct: 691 TDLEKKSIFYEEELSKRE-GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 749
Query: 495 MQIQTRELIKNIK--LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
Q + E K +KV+ E+ + L + + E+ + I Q L++E+ DL
Sbjct: 750 SQSEREEFESEFKQQYEREKVLLTEEN-KKLTSELDKLTTLYENLS-IHNQQLEEEVKDL 807
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG--QARVIKIREELINVLKN-----KE 605
K V H +++EI+ + +K++RG QA K+ EEL L+N +
Sbjct: 808 ADKKESVAHWEAQITEII-----QWVSDEKDARGYLQALASKMTEEL-EALRNSSLGTRA 861
Query: 606 TEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQE 642
T+ ++ + D+ R+ + ++ +I AK IQE
Sbjct: 862 TDMPWKMRRFAKLDMSARLELQSALDAEIRAK-QAIQE 898
Score = 53.2 bits (122), Expect = 3e-06
Identities = 90/414 (21%), Positives = 184/414 (44%), Gaps = 29/414 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA-EASITSLT 308
+N A E + KL + KL + ++ + + +D L + + I +L
Sbjct: 436 DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQ--YSTVDGPLTASKDLEIKNLK 493
Query: 309 GTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ L Q S E QLE A +R+ L +Q +LQ E + +++
Sbjct: 494 EEIEKLRKQVTESSHLEQQLE-EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELV 552
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIEELQA 422
+ + + K+ ++L++ Q K A+QE EI +R EL K++ ++D ++ +
Sbjct: 553 QASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ 612
Query: 423 KIIELEKSKPNPDLPTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ L + + ++E+++ E L A R ++ ++ E+E + G++QK
Sbjct: 613 KVESLRQELRRTE-RAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELE-GLKQKQ 670
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQYVRDLQA-HNRTIANCQESPNG 539
+ G I+ ++ I +K + E+K I YE+ + + H I N ++ +
Sbjct: 671 IS------YSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHD 724
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
Q L +EIM LK KL R E SE +++ E E + + R + + + ++L
Sbjct: 725 SEGQQLALNKEIMILKDKLEKT--RRESQSE---REEFESEFKQQYEREKVLLTEENKKL 779
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ L +K T L+ Q LE ++ + + + +A +I E+ + +++
Sbjct: 780 TSEL-DKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEK 832
>AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring protein
AKAP350 protein.
Length = 3595
Score = 74.1 bits (174), Expect = 1e-12
Identities = 94/414 (22%), Positives = 193/414 (46%), Gaps = 48/414 (11%)
Query: 232 VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
V +M + R+ + +E+ K EE+R L EE A+ + +L+ E + +
Sbjct: 1561 VTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKT 1620
Query: 292 KMDKQLREA-------EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT--GEVT 342
++Q++E E + + ++ LE + +Q + + E +R+ +E++K G V
Sbjct: 1621 LFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ-KEAMKAEAGPVE 1679
Query: 343 TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL 402
QL+Q+ + L E LE + Q EK + ++ LE D++ E R IEL
Sbjct: 1680 -QQLLQETEKLMKEKLEVQCQAEKDRDDLQKQVKALEIDVE----------EQVSRFIEL 1728
Query: 403 KERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLRVTEDE 461
++ TEL D R + L+ ++ ++ K + E E D++ E+Q ++ L+V
Sbjct: 1729 EQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVP-- 1786
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVR 521
+ + SE++ ++LA L K + ++ + +L ++I+ +++ + E VR
Sbjct: 1787 ----RFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVR 1842
Query: 522 DLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS---EILAKKDQELE 578
+L+ A D Q++ D K V ELS ++ A++D
Sbjct: 1843 ELEQALLVSA------------DTFQKVED--RKHFGAVEAKPELSLEVQLQAERDAIDR 1888
Query: 579 QQDKNSRGQARVIKIREELINVLKNKETEQ-SRELAALQQDLEHRMRIVDEVNK 631
++ + + + ++ + REEL N KN+E +Q +L +++ R++ +++ NK
Sbjct: 1889 KEKEITNLEEQLEQFREELEN--KNEEVQQLHMQLEIQKKESTTRLQELEQENK 1940
Score = 70.5 bits (165), Expect = 2e-11
Identities = 96/487 (19%), Positives = 217/487 (44%), Gaps = 61/487 (12%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALV---REVAKLRQDVETRNVMIDEIRELR 246
K + ++ + +L+ + E + + + + L + + +L++ + +N EI+ ++
Sbjct: 11 KEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN---QEIKNMK 67
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ--TRNRVAKMDKQLREAEASI 304
E N+K E E ++ + +K +SQ + + ++L + A +
Sbjct: 68 LELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAEL 127
Query: 305 TSLTGT--VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS---------- 352
+ G V+M ++ RQ Q+E + + ++ + S + D
Sbjct: 128 DEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINE 187
Query: 353 LQAEVLECKQQIEKLT------VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
L ++ + Q EKL ++ K A+Q+ EDL + +EQ + ++ I +E
Sbjct: 188 LNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESK 247
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E S + +E+L+A+I+ +S+ +L E E+ + K L + E E
Sbjct: 248 LNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNY------KIKLEMLEKEKNAVL 301
Query: 467 REKESENKIGIQQKLAAELL-NKEEIIGKMQ--IQTRELIKNIKLNEQKVIQYEQYVRDL 523
++ +E++ ++L +LL + EE + K++ ++ I KL + I Y+Q + L
Sbjct: 302 -DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGL 360
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
Q ++ Q+I ++ + +++ + +L ++K ++L+Q N
Sbjct: 361 Q------------------NEMSQKIETMQFEKDNLITKQNQLILEISKL-KDLQQSLVN 401
Query: 584 SRGQARVIKIRE--ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
S+ + ++I E + I +L+ +E E+ L+Q+++ + + KQ+ K +++Q
Sbjct: 402 SKSEEMTLQINELQKEIEILRQEEKEKG----TLEQEVQELQLKTELLEKQMKEKENDLQ 457
Query: 642 ELFATLE 648
E FA LE
Sbjct: 458 EKFAQLE 464
Score = 69.7 bits (163), Expect = 3e-11
Identities = 115/544 (21%), Positives = 236/544 (43%), Gaps = 58/544 (10%)
Query: 134 ENALELLDETMPIENIIKYPKTNL---TVNQDQTDGDILEHLSRYNDQGFELCGALRELK 190
E LE + ET K +T L + Q Q + L+ ++ E A +L
Sbjct: 1543 EKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLA 1602
Query: 191 TQ---AEDAVNTVTD---LSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
+ AE ++ D L +R E+ +I E + + Q++E I E RE
Sbjct: 1603 VELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERE 1662
Query: 245 LRSESENTKALE--EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
L S + E + +L +E T KL +KEKL E Q + ++R + KQ++ E
Sbjct: 1663 LLSRQKEAMKAEAGPVEQQLLQE-TEKL-MKEKL---EVQCQAEKDR-DDLQKQVKALEI 1716
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESL-KTGEVTTSQLI---QQRDSLQAEVL 358
+ LE + + + L + + L + L K + Q I +RD Q E+
Sbjct: 1717 DVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ 1776
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIE 418
+ +QQ+ K+ + + + +++Q L+E+ + + KE+ + ++Q+ IE
Sbjct: 1777 KLEQQL-KVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIE 1835
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+L+ ++ ELE++ L + +T + ED E + E + +Q
Sbjct: 1836 KLEFRVRELEQA-----------------LLVSADTFQKVEDRKHFGAVEAKPELSLEVQ 1878
Query: 479 QKLAAELLN-KEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
+ + ++ KE+ I ++ Q + + ++ ++V Q + + + T E
Sbjct: 1879 LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQE 1938
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEE------LSEILAKKDQELEQQDKNSRGQARVI 591
N + D+++ + L +K D + ++ ++I+ +K+ E++Q ++ +V
Sbjct: 1939 NKLFKDDMEK--LGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNE------QVT 1990
Query: 592 KIREELINVLKNKETEQSRELAA-LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
K++++L NK E+ EL L+ +E M + V + + +EI++L +E
Sbjct: 1991 KLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRN---REEEIEQLNEVIEKL 2047
Query: 651 QQQI 654
QQ++
Sbjct: 2048 QQEL 2051
Score = 59.3 bits (137), Expect = 5e-08
Identities = 83/413 (20%), Positives = 187/413 (45%), Gaps = 30/413 (7%)
Query: 174 RYNDQGFELCGALREL-KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
R +QG E A+ L K ++ + L + + TL E+ L ++
Sbjct: 2755 RIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNI 2814
Query: 233 ETRNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
+ + + E++ EL S + L+E +L E+ +K +L T+ +L T
Sbjct: 2815 QQKQSQMLEMQVELSSMKDRATELQE---QLSSEKMVVAELKSELAQTKLELETTLKAQH 2871
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
K K+L + T V +L D ++ ++R+L+ +L+ + + ++RD
Sbjct: 2872 KHLKELEAFRLEVKDKTDEVHLLNDTLASEQ----KKSRELQWALEKEKAKLGRS-EERD 2926
Query: 352 SLQAEVLECKQQIEKL-TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL 410
+ E L+ + +K +Q ++Q ++ L ++++ ++ Q + ++ ++ EL
Sbjct: 2927 KEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLEL 2986
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
Q +E + +I E+ + +RE +L A+LQ++ T + + + + KE
Sbjct: 2987 QV---LLESEKVRIREMSST-------LDRERELHAQLQSSDGTGQ-SRPPLPSEDLLKE 3035
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ ++ + ELLN+ E +QTR+ ++ + +K +Q EQ +A+
Sbjct: 3036 LQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQ-----EANTEGQ 3090
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK-KDQELEQQDK 582
E + + +DLQ+++ + + ++ + + L I+ + + QELE+++K
Sbjct: 3091 KKMHELQSKV--EDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEK 3141
Score = 53.2 bits (122), Expect = 3e-06
Identities = 100/442 (22%), Positives = 204/442 (46%), Gaps = 40/442 (9%)
Query: 181 ELCGALRELKTQAEDAV-NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMI 239
+L G L+E Q + N +L+ ER++ + + L+ V +L++ +
Sbjct: 47 KLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQ-LMGTVEELQKRNHKDSQFE 105
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTE-SQLRQTRNR-VAKMDKQ 296
+I + R E E + LE++R ELDE ++ +K++L +Q+ + + R +M+
Sbjct: 106 TDIVQ-RMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENA 164
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLE---ARARKLRESLKTGEVTTSQLIQQRDSL 353
LR + ++IT +K++ + ++L+ ++ KL+E L L +Q + L
Sbjct: 165 LR-SYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDL 223
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
E+ ++QI++ + I + E L + ++L E K EI + EL+
Sbjct: 224 VEELSFSREQIQRA----RQTIAEQESKLNEAHKSLST-VEDLKAEIVSASESRKELELK 278
Query: 414 RNA-IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT-EDEVTTCKREKES 471
A + + K+ LEK K N L E AEL+ + L + E+E++ K + E
Sbjct: 279 HEAEVTNYKIKLEMLEKEK-NAVLDRMAESQE-AELERLRTQLLFSHEEELSKLKEDLEI 336
Query: 472 ENKIGIQQ-KLAAELLNKEEIIG-----KMQIQTRELIKNIKLNEQKVIQYE-QYVRDLQ 524
E++I I++ K + K++I G +I+T + K+ + +Q + E ++DLQ
Sbjct: 337 EHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ 396
Query: 525 -------AHNRTIA-NCQESPNGISYQD------LQQEIMDLKMKLLDVVHRNEELSEIL 570
+ T+ N + I Q+ L+QE+ +L++K + + +E L
Sbjct: 397 QSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDL 456
Query: 571 AKKDQELEQQDKNSRGQARVIK 592
+K +LE ++ + + + ++
Sbjct: 457 QEKFAQLEAENSILKDEKKTLE 478
Score = 51.6 bits (118), Expect = 9e-06
Identities = 85/425 (20%), Positives = 185/425 (43%), Gaps = 33/425 (7%)
Query: 72 DRQAVLEVFQNLKSLYERLNNEGISACGE--GFLP-QELILFNVADWTAQEVAQLYRDAI 128
DR+++L Q +L+ ++N I+ E P QEL+ +N+ +Q L
Sbjct: 2774 DRRSLLSEIQ---ALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQ---MLEMQVE 2827
Query: 129 ASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRE 188
SS + A EL ++ + ++ K+ L QT ++ L + EL
Sbjct: 2828 LSSMKDRATELQEQLSSEKMVVAELKSELA----QTKLELETTLKAQHKHLKEL----EA 2879
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIR-ELRS 247
+ + +D + V L+ E++ + AL +E AKL + E +++++ L S
Sbjct: 2880 FRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLES 2939
Query: 248 ESENTKALE---EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+ + L E + +L E K+ + L ++QL + + R ++ L + I
Sbjct: 2940 QKQRNLQLNLLLEQQKQLLNESQQKIESQRMLY--DAQLSEEQGRNLELQVLLESEKVRI 2997
Query: 305 TSLTGTVKMLEDQSRQKEVQLEAR--ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
++ T+ D+ R+ QL++ + R L + ++ +L +Q + + ++E
Sbjct: 2998 REMSSTL----DRERELHAQLQSSDGTGQSRPPLPSEDLL-KELQKQLEEKHSRIVELLN 3052
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
+ EK + QQ+E+D + ++ LQ + E + +++++D + +EE +
Sbjct: 3053 ETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQ 3112
Query: 423 KI--IELEKSKPNPDLPTEREIDL-WAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
++ ++LE + + ++ +L E + ++ L +E TT + +QQ
Sbjct: 3113 QVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNWVLQQ 3172
Query: 480 KLAAE 484
K+ E
Sbjct: 3173 KIEGE 3177
Score = 44.0 bits (99), Expect = 0.002
Identities = 85/465 (18%), Positives = 202/465 (43%), Gaps = 39/465 (8%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
+R+L+TQ E +S + C +R + E L + KL+Q++ I + +
Sbjct: 2012 IRDLETQIECL------MSDQECVKRNREEEI-EQLNEVIEKLQQELAN----IGQKTSM 2060
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ S + +A + ++H+LD KLA+++++ T ++ +N + + + ++ + +
Sbjct: 2061 NAHSLSEEA-DSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELF 2119
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
SL + +E E + L + EV ++ D+L++ LE + +
Sbjct: 2120 SLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTE-----DALKS--LENQTYFK 2172
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQ-EQCEITKREIELKERTETELQDSRNAIEELQAKI 424
K +I LE L Q + + + E+T+ ++K+ E + E LQ KI
Sbjct: 2173 SFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQE----QGQFETEMLQKKI 2228
Query: 425 IELEK---SKPNPDLPTEREIDL---WAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+ L+K K L ++ +++ +A+ +T+ + + E+++G
Sbjct: 2229 VNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSD 2288
Query: 479 -QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
L + E + +M + +++ E+ V++ E+ + +LQ + + ++
Sbjct: 2289 ISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQ---KLLEGNEKKQ 2345
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEE---LSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ Q++ LK ++ H NEE +E+ A + + + + + + + + K++
Sbjct: 2346 REKEKKRSPQDVEVLK-TTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQ 2404
Query: 595 EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
EEL+ V + T ++L+ ++ L + + K+ + E
Sbjct: 2405 EELL-VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 2448
Score = 42.3 bits (95), Expect = 0.006
Identities = 67/317 (21%), Positives = 145/317 (45%), Gaps = 30/317 (9%)
Query: 357 VLEC-KQQIEKLTVQHKSAIQQLEE-DLKQTKRALQE-QCEITKREIELKERTETELQDS 413
+L C +Q+I++ V++++A++ L++ D + +Q ++ R+I LK E+E + S
Sbjct: 2748 LLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESE-KPS 2806
Query: 414 RNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+ +E +Q K ++ + + +R +L +L + K + + E+ K E E+
Sbjct: 2807 QELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETT 2866
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
K Q K EL +++ ++ + L + ++ R+LQ
Sbjct: 2867 LKA--QHKHLKEL-------EAFRLEVKDKTDEVHLLNDTLASEQKKSRELQ----WALE 2913
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARV-- 590
+++ G S + ++E+ DLK L RN +L+ +L ++ Q L + + Q +
Sbjct: 2914 KEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYD 2973
Query: 591 IKIREEL-----INVLKNKETEQSRELAAL---QQDLEHRMRIVDEV--NKQIAAKADEI 640
++ EE + VL E + RE+++ +++L +++ D ++ D +
Sbjct: 2974 AQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLL 3033
Query: 641 QELFATLENKQQQIHRL 657
+EL LE K +I L
Sbjct: 3034 KELQKQLEEKHSRIVEL 3050
Score = 40.3 bits (90), Expect = 0.023
Identities = 56/271 (20%), Positives = 122/271 (45%), Gaps = 19/271 (7%)
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKS--KPNPDLPTEREI--DLWAELQATK 452
+++ +++ + E+Q+ IEEL KIIE EK + L T ++ +L ++
Sbjct: 1 EQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN 60
Query: 453 ETLRVTEDEVTTCK-REKESENKIGIQQKLAAELLNKEEIIGKMQ---IQTRELIKNIKL 508
+ ++ + E+T K +E++S +I EL + + + +Q E KL
Sbjct: 61 QEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKL 120
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
+ + E Y + + + + Q + + M+ ++ + NE+ +
Sbjct: 121 EQLRAELDEMYGQQIVQMKQELIR-QHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIK 179
Query: 569 IL--AKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIV 626
++ A + ++ QD NS+ + K++EEL +L+ K Q R+L L ++L +
Sbjct: 180 LMNVAINELNIKLQDTNSQKE----KLKEELGLILEEKCALQ-RQLEDLVEELSFSREQI 234
Query: 627 DEVNKQIA---AKADEIQELFATLENKQQQI 654
+ IA +K +E + +T+E+ + +I
Sbjct: 235 QRARQTIAEQESKLNEAHKSLSTVEDLKAEI 265
Score = 36.7 bits (81), Expect = 0.28
Identities = 108/571 (18%), Positives = 240/571 (42%), Gaps = 37/571 (6%)
Query: 117 AQEVAQLYRDAIASSTPENALELLDETMPIENI-IKYP--KTNLTVNQDQTDGDILEHLS 173
+QE ++ D+I S + ++ E E + EN +K + N + + + E
Sbjct: 488 SQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNF 547
Query: 174 RYNDQGF-ELCGALRELKTQAEDAVNT--VTDLSK-RACHERRTLIAVGEALVREVAKLR 229
N Q E L ++K ED+ N + SK +A +E L + V+ + +
Sbjct: 548 EVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 607
Query: 230 QDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNR 289
+ +T + E E+ E K E+ +L+ + KL + ++L+ QL+Q
Sbjct: 608 DEDKT---FVAETLEMGEVVE--KDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGE 662
Query: 290 VAKMD---KQLREAEASITSLTGTVKMLEDQSRQKEVQ-LEARARKLRESLKT-----GE 340
++ ++ K L++ + ++ ++++ + +R + VQ + + L + + T E
Sbjct: 663 ISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAE 722
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED-----LKQTKRALQEQCEI 395
+ S++ + ++E K E +TV +S +QL D K++ + E
Sbjct: 723 GSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSEN 782
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
K + EL ++E D R +E Q + L S + E + L + KE L
Sbjct: 783 DKLQKELNV-LKSEQNDLRLQMEA-QRICLSLVYSTHVDQVREYMENEKDKALCSLKEEL 840
Query: 456 RVTEDE-VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI 514
++E + ++ + E + Q+ E +IGK+Q E V+
Sbjct: 841 IFAQEEKIKELQKIHQLELQTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVL 900
Query: 515 --QYEQYVR-DLQAHNRTIANCQESPN-GISYQDLQQEIMDLKMKLLDVVHR-NEELSEI 569
Y ++ ++ A ++ + S N QD + E+ D + + ++++ EE +++
Sbjct: 901 GEYYTPALKCEVNAEDKENSGDYISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKL 960
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ-DLEHRMRIVDE 628
L + + + + + G ++ EE + + + ++ L+ D+ H+ ++
Sbjct: 961 LVLQTRLSKIWGQQTDGMK--LEFGEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSL 1018
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ + +++QEL + + + QQQ+ E+
Sbjct: 1019 QDLEKTKLEEQVQELESLISSLQQQLKETEQ 1049
Score = 35.5 bits (78), Expect = 0.64
Identities = 88/449 (19%), Positives = 202/449 (44%), Gaps = 50/449 (11%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E+ E+ T +L EKL T+ + + R++ + +QL++ I+ L VK L+ + Q
Sbjct: 622 EVVEKDTTELM--EKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQ 679
Query: 321 KEV---QLEARARKLR-ESLKTGEVTTSQLI--------QQRDSLQAEVLECKQQIEKLT 368
+ +LE R E++++ + S L+ + + ++V + + K+
Sbjct: 680 VSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIM 739
Query: 369 VQHKSAIQQLE--EDLKQTKRALQEQCEITKR-EIELKERTETE-LQDSRNAIEELQAKI 424
V+ K + + + E+ KQ + L +TK + + +E + LQ N ++ Q +
Sbjct: 740 VEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDL 799
Query: 425 -IELEKSKPNPDLPTEREIDLWAELQATK--ETLRVTEDEVTTCKREKESE----NKIGI 477
+++E + L +D E + + L ++E+ + EK E +++ +
Sbjct: 800 RLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFAQEEKIKELQKIHQLEL 859
Query: 478 QQKLAAELLNKEE----IIGKMQIQTRELIKNIKLNEQKVI--QYEQYVR-DLQAHNRTI 530
Q E ++ + +IGK+Q E V+ Y ++ ++ A ++
Sbjct: 860 QTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKEN 919
Query: 531 ANCQESPN-GISYQDLQQEIMDLKMKLLDVVHR-NEELSEILAKKDQ------------E 576
+ S N QD + E+ D + + ++++ EE +++L + + +
Sbjct: 920 SGDYISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMK 979
Query: 577 LEQQDKN-SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAA 635
LE ++N + + + I ++ N L++ + +L++L QDLE + ++ ++V + +
Sbjct: 980 LEFGEENLPKEETEFLSIHSQMTN-LEDIDVNHKSKLSSL-QDLE-KTKLEEQVQELESL 1036
Query: 636 KADEIQELFATLENKQQQIHRLEKIVLAL 664
+ Q+L T +N + +IH L+K + A+
Sbjct: 1037 ISSLQQQLKETEQNYEAEIHCLQKRLQAV 1065
>AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein
kinase alpha variant protein.
Length = 1702
Score = 74.1 bits (174), Expect = 1e-12
Identities = 83/354 (23%), Positives = 164/354 (46%), Gaps = 21/354 (5%)
Query: 319 RQKEVQLEARARKLRESLKTGEVTTSQLIQQ--RDSLQAEVLECKQQIEKLTVQHKSAIQ 376
R ++ +LE +RKL+ES +T + + S E+ K++IEKL Q +
Sbjct: 461 RLEQEKLEL-SRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTES-S 518
Query: 377 QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI--EELQAKIIELEKSKPNP 434
LE+ L++ A++++ + R+I+ E+ LQ R + E +QA +SK
Sbjct: 519 HLEQQLEEAN-AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELK 577
Query: 435 DLPTEREIDL--WAELQATKETLRVTEDEVTTCKREKESENKIGIQ--QKLAAELLNKEE 490
D +R++ + + E+ L + ++ R+KE E + +Q + L EL E
Sbjct: 578 DAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTER 637
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GISYQDLQQEI 549
++++ T L + + Q E Y + L+ + Q S + G+ + QQEI
Sbjct: 638 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 697
Query: 550 MDLKMKL-LDVVHRNEELSE---ILAKKDQELEQQDKNSRGQA-----RVIKIREELINV 600
LK L + EELS+ I A + + L+++ +S GQ ++ ++++L
Sbjct: 698 TKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKT 757
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++E+ + +Q E ++ E NK++ ++ D++ L+ L QQ+
Sbjct: 758 RRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQL 811
Score = 56.8 bits (131), Expect = 2e-07
Identities = 92/458 (20%), Positives = 203/458 (44%), Gaps = 33/458 (7%)
Query: 202 DLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+LS++ +T+ A+ + V +D+E +N+ +EI +LR + + LE+ E
Sbjct: 468 ELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLK-EEIEKLRKQVTESSHLEQQLEE 526
Query: 262 LDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQK 321
+ R ++ E Q++ + ++K+L +A + + + K L+D Q+
Sbjct: 527 ANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQS---KELKDAHCQR 583
Query: 322 EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++ ++ ++ E L +L + + EV Q++E L Q ++ +++
Sbjct: 584 KLAMQ-EFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLR-QELRRTERAKKE 641
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK----IIELEKSKPNPDLP 437
L+ AL + ++ E E +L++ +++ Q + +E + L
Sbjct: 642 LEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLK 701
Query: 438 TERE-IDLWAELQATKETLRVTEDEVTTCKRE-KESE-NKIGIQQKLAAELLNKEEIIGK 494
T+ E ++ E + +K + +E+ K+E +SE ++ + +++ E+ +
Sbjct: 702 TDLEKKSIFYEEELSKRE-GIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLEKTRRE 760
Query: 495 MQIQTRELIKNIK--LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
Q + E K +KV+ E+ + L + + E+ + I Q L++E+ DL
Sbjct: 761 SQSEREEFESEFKQQYEREKVLLTEEN-KKLTSELDKLTTLYENLS-IHNQQLEEEVKDL 818
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG--QARVIKIREELINVLKN-----KE 605
K V H +++EI+ + +K++RG QA K+ EEL L+N +
Sbjct: 819 ADKKESVAHWEAQITEII-----QWVSDEKDARGYLQALASKMTEEL-EALRNSSLGTRA 872
Query: 606 TEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQE 642
T+ ++ + D+ R+ + ++ +I AK IQE
Sbjct: 873 TDMPWKMRRFAKLDMSARLELQSALDAEIRAK-QAIQE 909
Score = 53.2 bits (122), Expect = 3e-06
Identities = 90/414 (21%), Positives = 184/414 (44%), Gaps = 29/414 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA-EASITSLT 308
+N A E + KL + KL + ++ + + +D L + + I +L
Sbjct: 447 DNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQ--YSTVDGPLTASKDLEIKNLK 504
Query: 309 GTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ L Q S E QLE A +R+ L +Q +LQ E + +++
Sbjct: 505 EEIEKLRKQVTESSHLEQQLE-EANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELV 563
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIEELQA 422
+ + + K+ ++L++ Q K A+QE EI +R EL K++ ++D ++ +
Sbjct: 564 QASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ 623
Query: 423 KIIELEKSKPNPDLPTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K+ L + + ++E+++ E L A R ++ ++ E+E + G++QK
Sbjct: 624 KVESLRQELRRTE-RAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELE-GLKQKQ 681
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQYVRDLQA-HNRTIANCQESPNG 539
+ G I+ ++ I +K + E+K I YE+ + + H I N ++ +
Sbjct: 682 IS------YSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHD 735
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
Q L +EIM LK KL R E SE +++ E E + + R + + + ++L
Sbjct: 736 SEGQQLALNKEIMILKDKLEKT--RRESQSE---REEFESEFKQQYEREKVLLTEENKKL 790
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
+ L +K T L+ Q LE ++ + + + +A +I E+ + +++
Sbjct: 791 TSEL-DKLTTLYENLSIHNQQLEEEVKDLADKKESVAHWEAQITEIIQWVSDEK 843
>AB067524-1|BAB67830.1| 704|Homo sapiens KIAA1937 protein protein.
Length = 704
Score = 74.1 bits (174), Expect = 1e-12
Identities = 91/425 (21%), Positives = 197/425 (46%), Gaps = 35/425 (8%)
Query: 244 ELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
+LR + L E R E +E+ AK+ + E+ E + Q RNR + ++ R+
Sbjct: 20 KLREHLAEKEKLNEERLEQEEKLKAKIRQLTEEKAALEEYITQERNRAKETLEEERKRMQ 79
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
+ SL L Q + + +++E+L+ E T Q +++R + Q E+ E
Sbjct: 80 ELESL------LAQQKKALAKSITQEKNRVKEALEE-EQTRVQELEERLARQKEISESNI 132
Query: 363 QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
EK K A+++ ++ ++ + L +Q K E+ELKE+ E L N + + A
Sbjct: 133 AYEKRKA--KEAMEKEKKKVQDLENRLTKQ----KEELELKEQKEDVL---NNKLSDALA 183
Query: 423 KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI--GIQQK 480
+ E +K+K L E L +L T L T+ ++ + + K+ +Q +
Sbjct: 184 MVEETQKTKATESLKAE---SLALKLNETLAELETTKTKMIMVEERLILQQKMVKALQDE 240
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGI 540
++ E I + + Q ++ + I E+K+ + Q+ + ++ T+ + +P
Sbjct: 241 QESQRHGFGEEIMEYKEQIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLKDNDPAPKEE 300
Query: 541 SYQD-LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELIN 599
QD L + + K + H + ++LA + + L QQ+ ++K+R++L
Sbjct: 301 RPQDPLVAPMTESSAKDMAYEHL---IDDLLAAQKEILSQQEV-------IMKLRKDLTE 350
Query: 600 VLKNKETEQSRELAALQQ-DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ ++ EL Q+ +LE + +V + +K+++ +++ ++ + +E K +++ LE
Sbjct: 351 A-HSRMSDLRGELNEKQKMELEQNVVLVQQQSKELSVLKEKMAQMSSLVEKKDRELKALE 409
Query: 659 KIVLA 663
+ + A
Sbjct: 410 EALRA 414
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 73.7 bits (173), Expect = 2e-12
Identities = 109/558 (19%), Positives = 240/558 (43%), Gaps = 41/558 (7%)
Query: 166 GDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV 225
G+ LS ++ +L + +L+ + E ++++ R ++ + +
Sbjct: 2100 GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLE 2159
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+L+ E + ++I + ++E E K +EEM L + ++ + Q++
Sbjct: 2160 RELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQ 2219
Query: 285 QTRNRVAKMDKQL----------REAEASITSLTGT-VKMLEDQSRQKEVQLEARARKLR 333
+ + +++++DK L +AE I + T V+ML++Q ++ + A +
Sbjct: 2220 EKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGD-Q 2278
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
E +K E + I++ L+ + + + ++E + +QQL+E + L+ +
Sbjct: 2279 EIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKES-EHHADLLKGRV 2337
Query: 394 EITKREIEL----KERTETELQDSRNAIEELQAKIIELEKSKPNPDLP-----TEREIDL 444
E +RE+E+ +E E ++S+ +E L+AKI + +S +L +E+E +L
Sbjct: 2338 ENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKE-NL 2396
Query: 445 WAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
ELQ KE R++E E+ E + K +Q+ + +Q Q +EL +
Sbjct: 2397 TNELQ--KEQERISELEIINSSFENILQEK---EQEKVQMKEKSSTAMEMLQTQLKELNE 2451
Query: 505 NIKL--NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ N+Q+ + ++ Q + Q G+ + + + L+ + ++
Sbjct: 2452 RVAALHNDQEACKAKEQNLSSQVECLELEKAQ-LLQGL--DEAKNNYIVLQSSVNGLIQE 2508
Query: 563 NEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
E+ + L KKD+E+ + + Q +++ + + EQ+ EL L +LE +
Sbjct: 2509 VEDGKQKLEKKDEEISRLKNQIQDQEQLVS-KLSQVEGEHQLWKEQNLELRNLTVELEQK 2567
Query: 623 MRIVDEVNKQIAAKADEIQELFATLEN-----KQQQIHRLEKIVLALXXXXXXXXXXXXX 677
++++ N + + +Q + LEN K ++ +EK V +
Sbjct: 2568 IQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VNKMTAKETELQREMHE 2626
Query: 678 XXXKIAALEHELAAGLNR 695
K A L+ EL+ NR
Sbjct: 2627 MAQKTAELQEELSGEKNR 2644
Score = 67.3 bits (157), Expect = 2e-10
Identities = 106/541 (19%), Positives = 234/541 (43%), Gaps = 35/541 (6%)
Query: 147 ENIIKYPKTNLTVNQD--QTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLS 204
E + + ++ T++Q+ Q + + L + + L L +L + + N + +
Sbjct: 398 EELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFK 457
Query: 205 KRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS-ESENTKA-LEEMRHEL 262
++ C + A + E+ + ++++ N ++ E ++ E + +A L+ ++ L
Sbjct: 458 QKLCRAEQAFQA-SQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCL 516
Query: 263 DEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--REAEASITSLTGTVKMLEDQSRQ 320
++ + +K K T+ E+ LR + ++ + + L + + ++ L +D ++
Sbjct: 517 NQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKK 576
Query: 321 KEVQLEARARKLRESLKTGEVTTSQL-IQQRD-SLQAE--VLEC-KQQIEKLTVQHKSAI 375
+E +E KL ++ K + S L +++++ L+ E + C K + EKL Q +S
Sbjct: 577 REHHIEQLNDKLSKTEKESKALLSALELKKKEYELKEEKTLFSCWKSENEKLLTQMESEK 636
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERT-----ETELQDSRNAIEELQAKIIELEKS 430
+ L+ + + L+ Q +I E + RT E + RN L +K +E+E
Sbjct: 637 ENLQSKINHLETCLKTQ-QIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQ 695
Query: 431 KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE 490
K E+ AE K + + T + + E+ Q L+ E+++K+
Sbjct: 696 KL-----AYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDR 750
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ-DLQQEI 549
+ + L +K + ++ E + R L A ++ A N I Q + E
Sbjct: 751 CYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSER 810
Query: 550 MDLKMKLLDVVHRNEELSEILAKKDQELEQQDK-NSRGQAR---VIKIREELI-NVLKNK 604
+ +++ + L + + LE Q + NS Q + +++I+ E+ N++K +
Sbjct: 811 SECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAE 870
Query: 605 ETEQS------RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ QS + ++ LQ+D +V E + K E+Q L +E +Q +I L+
Sbjct: 871 QMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELK 930
Query: 659 K 659
K
Sbjct: 931 K 931
Score = 58.4 bits (135), Expect = 8e-08
Identities = 86/363 (23%), Positives = 158/363 (43%), Gaps = 29/363 (7%)
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
+ S+ S ++ DQS + L+ R L SL++ + S L +Q + L E
Sbjct: 803 QGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEI 862
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
++ + K H+S + + + + + + + + E E ELQ + +E
Sbjct: 863 EENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETE 922
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC----KRE-KESENKI 475
QA+I EL+KS + D ELQ ETL + + E+++ KRE +E +
Sbjct: 923 QAEIQELKKSNHLLE-------DSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 975
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G +++ A LN+E++ IQ E N +K I E + Q + C+E
Sbjct: 976 GTLKEINAS-LNQEKM---NLIQKSESFANYIDEREKSIS-ELSDQYKQEKLILLQRCEE 1030
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
+ N +Y+DL Q+ + K + E + + + ELEQ +A + +E
Sbjct: 1031 TGN--AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLK-----EAFAKEHQE 1083
Query: 596 ELINVLKNKETEQS--RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ 653
L + +E Q+ EL +QQ L R + D N ++A +++ TL+ +Q +
Sbjct: 1084 FLTKLAFAEERNQNLMLELETVQQAL--RSEMTDNQNNS-KSEAGGLKQEIMTLKEEQNK 1140
Query: 654 IHR 656
+ +
Sbjct: 1141 MQK 1143
Score = 57.2 bits (132), Expect = 2e-07
Identities = 83/436 (19%), Positives = 197/436 (45%), Gaps = 31/436 (7%)
Query: 248 ESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
E+EN+K +E ++ +++ + ++ + T S+ N + K +++ E E +S
Sbjct: 2357 EAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSS 2416
Query: 307 LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
++ E + Q + + L+ LK + L +++ +A+ Q+E
Sbjct: 2417 FENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVEC 2476
Query: 367 LTVQHKSAIQQLEED------LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
L ++ +Q L+E L+ + L ++ E K+++E K+ + L++ E+L
Sbjct: 2477 LELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQL 2536
Query: 421 QAKIIEL--------EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+K+ ++ E++ +L E E + LQ+ +L+ T + + + + E+E
Sbjct: 2537 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQV-LQSKNASLQDTLEVLQSSYKNLENE 2595
Query: 473 NKIGIQQKLA-AELLNKEEI-IGKMQIQTRELI-KNIKLNEQKVIQYEQYVRDLQAHNRT 529
++ K++ E +NK ++Q + E+ K +L E+ + + +LQ
Sbjct: 2596 LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEE 2655
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK---DQELEQQDKNSRG 586
I + ++ ++L E +LK K LD +H+++ E ++ + +L + +
Sbjct: 2656 IKSSKD-----QLKELTLENSELK-KSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 2709
Query: 587 QARVI---KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
QA ++ K E I + K T + L++ + +++ +E+N + A ++EL
Sbjct: 2710 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEEL 2769
Query: 644 FATLENKQQQIHRLEK 659
T + + +++L+K
Sbjct: 2770 KKTKMDNLKYVNQLKK 2785
Score = 56.4 bits (130), Expect = 3e-07
Identities = 89/435 (20%), Positives = 196/435 (45%), Gaps = 27/435 (6%)
Query: 230 QDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNR 289
Q+ E RN I+E+ ELR + K ++ ++ E + K +L E L + R+
Sbjct: 286 QNQELRN-KINEL-ELRLQGHE-KEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDE 342
Query: 290 VAKMDKQLREAEASITSLTGTVKML-EDQSRQKEVQLEARA---RKLRESLKTGEVTTSQ 345
+ + Q +A T+L +K L ED S Q++ AR +K++E K + S+
Sbjct: 343 LVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSR 402
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE- 404
+ +L E ++ K ++ + Q K+ L+ +L + ++++Q E E + K
Sbjct: 403 QQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKL-TSVKQQLENNLEEFKQKLC 461
Query: 405 RTETELQDSRNAIEELQAKIIELEKS----KPNPDLPTEREIDLWAELQATKETLRVTED 460
R E Q S+ EL+ + E++K K + + L AEL+ K+ L +++
Sbjct: 462 RAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQN 521
Query: 461 EVTTCKREKESENKI--GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ 518
K + S+ + +Q+K+ + + K+++ +L K ++ + + E
Sbjct: 522 FAEEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREH 579
Query: 519 YVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELE 578
++ Q +++ +ES +S +L+++ +LK + E ++L + + E E
Sbjct: 580 HIE--QLNDKLSKTEKESKALLSALELKKKEYELKEEKTLFSCWKSENEKLLTQMESEKE 637
Query: 579 QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
Q+++ + E + + K E + + L+ D E+ + ++ + +K+
Sbjct: 638 NL------QSKINHL-ETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSV 690
Query: 639 EIQ-ELFATLENKQQ 652
E++ + A +E +Q+
Sbjct: 691 EVETQKLAYMELQQK 705
Score = 51.6 bits (118), Expect = 9e-06
Identities = 87/430 (20%), Positives = 180/430 (41%), Gaps = 40/430 (9%)
Query: 257 EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED 316
E R E D+ ++ ++ + E L + + + KQ E + + E
Sbjct: 812 ECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQ 871
Query: 317 QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV--LECKQQIEKLTVQHKSA 374
+ + R KL+E + ++ + ++ + E+ L K + E+ +Q
Sbjct: 872 MHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKK 931
Query: 375 IQQLEEDLKQTKRALQEQCEITKRE----IELKERTETELQDSRNAIEELQAKIIE---- 426
L ED + + L E + K+E I L +R EL ++E+ A + +
Sbjct: 932 SNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMN 991
Query: 427 -LEKSKPNPDLPTEREIDLWAEL--QATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
++KS+ + ERE + +EL Q +E L + + C+ + + + K A
Sbjct: 992 LIQKSESFANYIDEREKSI-SELSDQYKQEKLILLQ----RCEETGNAYEDLSQKYKAAQ 1046
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
E +K E + + L +N K NE + ++ E + ++ Q +A +E + +
Sbjct: 1047 EKNSKLECLLN---ECTSLCENRK-NELEQLK-EAFAKEHQEFLTKLAFAEERNQNLMLE 1101
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL---EQQDKNSRGQARVIKIREELINV 600
L+ L+ ++ D ++N SE K + + E+Q+K + +++ E+L+ V
Sbjct: 1102 -LETVQQALRSEMTD--NQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKV 1158
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVN---------KQIAAKADEIQ--ELFATLEN 649
+K K Q+ E ++ ++ R ++ N K+I+ + Q +L A L N
Sbjct: 1159 MKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRN 1218
Query: 650 KQQQIHRLEK 659
K+ ++ EK
Sbjct: 1219 KELKLQESEK 1228
Score = 46.4 bits (105), Expect = 3e-04
Identities = 59/224 (26%), Positives = 104/224 (46%), Gaps = 31/224 (13%)
Query: 224 EVAKLRQDV----ETRNVMIDEIRELRSESENTKALEEMRHELD--EERTAKLAIKEKLT 277
E L+Q++ E +N M E+ +L E+E + + +HE E + ++KE+
Sbjct: 1123 EAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKER-- 1180
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRE 334
ES+ Q N +MD +++ E S+ S + LE R KE++L+ ++ L+
Sbjct: 1181 --ESERNQC-NFKPQMDLEVK--EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQH 1235
Query: 335 SLKT--GEVTTSQLIQQRDSLQAEVLECKQQIEK--LTVQHKSAIQQ-----LEEDLKQT 385
L+T G++ TS L + + + +C+ E+ ++ H+ + Q L+ L+ T
Sbjct: 1236 ELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTT 1295
Query: 386 KRALQEQ---CEITKREIELKERTETELQDSRNAIEELQAKIIE 426
L E CEI + E K TEL DSR+ K+ E
Sbjct: 1296 MNKLNELEKICEILQAE---KYELVTELNDSRSECITATRKMAE 1336
Score = 39.5 bits (88), Expect = 0.039
Identities = 57/298 (19%), Positives = 132/298 (44%), Gaps = 27/298 (9%)
Query: 134 ENALEL--LDETMPIENIIKYPKTNLTVNQD-----QTDGDILEHLSRYNDQGFELCGAL 186
EN LEL +D+ +E + K + ++ Q ++ E LS ++ L G L
Sbjct: 2593 ENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNR---LAGEL 2649
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE-- 244
+ L + + + + + +L+ +++L + + V + K+R+++ + + E +
Sbjct: 2650 QLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 2709
Query: 245 ----LRSESENTKALEEMRHELDEER----TAKLAIKEKLTTTESQLRQTRNRVAKMDKQ 296
L + + ++ R +L + + KL I + L +++ +L + ++ ++
Sbjct: 2710 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEI-DLLKSSKEELNNSLKATTQILEE 2768
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL-IQQRDSLQA 355
L++ + +K ++++ K L ++L E + + SQL Q
Sbjct: 2769 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTG 2828
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE--ITKREIE-LKERTETEL 410
V++ K +++LT + K + LEE K+ L + C I+ ++E KE ET++
Sbjct: 2829 TVMDTK--VDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQV 2884
Score = 37.1 bits (82), Expect = 0.21
Identities = 80/436 (18%), Positives = 188/436 (43%), Gaps = 29/436 (6%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTESQ 282
E +L +E R+ ++ + E ++ L+E++ E +L I +L S
Sbjct: 1781 ENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSD 1840
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG--- 339
L + + ++L + + L ++M D+S ++++ K+ +S K
Sbjct: 1841 LSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIG--DNVAKVNDSWKERFLD 1898
Query: 340 -EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-TK 397
E S++ ++ S++ E L + +E + + K +++ E+ ++ L+E+ + T
Sbjct: 1899 VENELSRIRSEKASIEHEALYLEADLEVVQTE-KLCLEKDNENKQKVIVCLEEELSVVTS 1957
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLR 456
+L+ +T + A+++L K+ E + + I + AE++ E L+
Sbjct: 1958 ERNQLRGELDT-MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQ 2016
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI-KLNEQKVIQ 515
+V+ ++K +Q+KL + L K+ + + EL I +LN++K
Sbjct: 2017 TLSSDVSELLKDKTH-----LQEKLQS--LEKDS--QALSLTKCELENQIAQLNKEK--- 2064
Query: 516 YEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI---LAK 572
E V++ ++ ++ +S + L+ +++ L + EE+ ++ + K
Sbjct: 2065 -ELLVKESESLQARLSESDYEKLNVS-KALEAALVEKGEFALRLSSTQEEVHQLRRGIEK 2122
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ 632
+E +K A +K RE + LK+K REL +++ E + + +
Sbjct: 2123 LRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAE 2182
Query: 633 IAAKADEIQELFATLE 648
+ +I+E+ +L+
Sbjct: 2183 VETLKTQIEEMARSLK 2198
Score = 36.7 bits (81), Expect = 0.28
Identities = 56/263 (21%), Positives = 119/263 (45%), Gaps = 13/263 (4%)
Query: 232 VETRNVMIDEIRELRSES-ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
VE N M + EL+ E E + E++ EL E+ +LA + +L E ++ +++++
Sbjct: 2607 VEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKN-RLAGELQLLLEE--IKSSKDQL 2663
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
++ + E + S+ + E + R++ + + R + + + + T++ +
Sbjct: 2664 KELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVE 2723
Query: 351 DSLQAEVLECKQQI---EKLTVQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
E L K++ +KL + KS+ ++L LK T + L+E + ++ +
Sbjct: 2724 IQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQL 2783
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTE-REIDLWAELQATKETLRVTEDEVTTC 465
+ E + ++ ++ L +LE+ K L E ++ E Q T + DE+TT
Sbjct: 2784 KKENERAQGKMKLLIKSCKQLEEEK--EILQKELSQLQAAQEKQKTGTVMDTKVDELTT- 2840
Query: 466 KREKESENKIGIQQKLAAELLNK 488
KE + + + K A E L+K
Sbjct: 2841 -EIKELKETLEEKTKEADEYLDK 2862
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 73.7 bits (173), Expect = 2e-12
Identities = 107/498 (21%), Positives = 220/498 (44%), Gaps = 34/498 (6%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
ALR+ ++ + + + + A + + L A + + + ++++ R + + ++E
Sbjct: 778 ALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE 837
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
SE K E ++ +E+ A+ + E+ + + +++T N++ + ++Q + +
Sbjct: 838 NLSEVSQVKETLEKELQILKEKFAEAS--EEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 895
Query: 305 TSLTGTVKMLEDQSRQK---EVQLEARARKLR----ESLKTGEVTTSQLIQQRDSLQAEV 357
L + +E + R+K E QL KL E +K SQL + D L+ +
Sbjct: 896 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKE 955
Query: 358 LECKQQIEKLTVQHKSA--IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
+ ++ KLT +++A +Q+ ED+ T +A Q Q E K+ E K+ E +L D
Sbjct: 956 RDVEELQLKLTKANENASFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKELERKLSDLEK 1013
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+E + EL+ T+ + + LQ ++TL TED++ + E
Sbjct: 1014 KMETSHNQCQELKARYERATSETKTKHE--EILQNLQKTLLDTEDKLKGAREENS----- 1066
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G+ Q+L E L K+ K QT E +++ EQ + + + L+ +T A Q
Sbjct: 1067 GLLQEL--EELRKQAEKAK-AAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQN 1121
Query: 536 SPNGISYQDLQQ-EIMDLKMKLLDVVHRNEE--LSEILAKKDQELEQQDKNSRGQARVIK 592
+ + +L+ E ++ +LL V ++ E EI K ++ + S Q +K
Sbjct: 1122 ELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVK 1181
Query: 593 IREEL----INVLKNKETEQSRELA--ALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
+ EEL V +++ E+ R + L + + + + + +++ A+ I A
Sbjct: 1182 LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSAL 1241
Query: 647 LENKQQQIHRLEKIVLAL 664
L K ++ +L V L
Sbjct: 1242 LTEKDAELEKLRNEVTVL 1259
Score = 70.1 bits (164), Expect = 2e-11
Identities = 103/480 (21%), Positives = 215/480 (44%), Gaps = 36/480 (7%)
Query: 186 LRELKTQAEDAVNTVTDLSKRA-CHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
+ EL+ V V +L +R ++ + + +L++E++ L++ +E D RE
Sbjct: 512 IMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRT--DHQRE 569
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+ S E+ A EE H+ +E A EKL+ L+ +++ +K+ + A
Sbjct: 570 ITSLKEHFGAREET-HQ--KEIKALYTATEKLSKENESLK---SKLEHANKENSDVIALW 623
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
S T + Q +E+++ E+ + E+ T Q+ + R Q E+ + Q
Sbjct: 624 KSKLETA-IASHQQAMEELKVSFSKGLGTETAEFAELKT-QIEKMRLDYQHEIENLQNQQ 681
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTE-TELQDSRNAIEELQAK 423
+ H ++ L L + + + E + +++ E E++D+ N ++E + K
Sbjct: 682 DSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIK 741
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
+ ELE + + T+ + ++L+AT+E L + D + E +SE K QQ AA
Sbjct: 742 VKELEVLQAKCNEQTKVIDNFTSQLKATEEKL-LDLDALRKASSEGKSEMKKLRQQLEAA 800
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISY- 542
E QI+ E+ KN + ++ I R+LQ + N QE+ + +S
Sbjct: 801 E----------KQIKHLEIEKNAESSKASSI-----TRELQGRELKLTNLQENLSEVSQV 845
Query: 543 -QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINV 600
+ L++E+ LK K + + + + +L Q+++ + + + K+RE L ++
Sbjct: 846 KETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADM 905
Query: 601 -LKNKE-TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
K +E E+ +L ++ LE+ + E+ K ++ ++ L K++ + L+
Sbjct: 906 EAKFREKDEREEQLIKAKEKLEND---IAEIMKMSGDNPSQLTKMNDELRLKERDVEELQ 962
Score = 64.1 bits (149), Expect = 2e-09
Identities = 109/505 (21%), Positives = 214/505 (42%), Gaps = 60/505 (11%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDE--ERTAKLAIKEKL 276
EA RE +L +E +++++ E TK E + ++ E E T ++
Sbjct: 418 EAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARI 477
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
E L + + K+ ++L + + S + LE + ++ R+L +
Sbjct: 478 KELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNK 537
Query: 337 KTGEVTTS-QLIQQRDSL-----------QAEVLECKQQIEKLTVQHKSAIQQL---EED 381
G+V S L+Q+ SL Q E+ K+ H+ I+ L E
Sbjct: 538 PAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEK 597
Query: 382 LKQTKRALQEQCEITKRE----IEL-KERTETELQDSRNAIEELQ-----------AKII 425
L + +L+ + E +E I L K + ET + + A+EEL+ A+
Sbjct: 598 LSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFA 657
Query: 426 ELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE---KESENKI-GIQQKL 481
EL+ L + EI+ Q ++ E E K KE EN + I+ KL
Sbjct: 658 ELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKL 717
Query: 482 -AAE---LLNKEEIIGKMQ---IQTREL-IKNIKLNEQ-KVIQ--------YEQYVRDLQ 524
AE L+ E+ + K+Q I+ +EL + K NEQ KVI E+ + DL
Sbjct: 718 DKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLD 777
Query: 525 AHNRTIANCQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
A + + + + Q +++I L+++ + ++ L ++ +L +
Sbjct: 778 ALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQE 837
Query: 583 NSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ---IAAKADE 639
N ++V + E+ + +LK K E S E ++Q+ ++ + + + +Q +++ ++
Sbjct: 838 NLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEK 897
Query: 640 IQELFATLENK-QQQIHRLEKIVLA 663
++E A +E K +++ R E+++ A
Sbjct: 898 LRENLADMEAKFREKDEREEQLIKA 922
Score = 43.2 bits (97), Expect = 0.003
Identities = 77/358 (21%), Positives = 155/358 (43%), Gaps = 32/358 (8%)
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARAR 330
A++ + TT + L+ R+ A + +S++S +L + S + ++
Sbjct: 295 AVRRVMATTSASLK--RSPSASSLSSMSSVASSVSSRPSRTGLLTETSSRYARKISGTTA 352
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
L+E+LK + QL+ +RD +AEV + + ++ + A ++ + + + +
Sbjct: 353 -LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMD 411
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + K +L++ + +E+LQ ++ E+S DL + +I E
Sbjct: 412 QLRTMVEAADREKVELLNQLEEEKRKVEDLQFRV--EEESITKGDLEQKSQISEDPENTQ 469
Query: 451 TK-ETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
TK E R+ E E + + +++ KL EL + + + EL K++ L
Sbjct: 470 TKLEHARIKELEQSLLFEKTKAD-------KLQRELEDTRVATVSEKSRIMELEKDLALR 522
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
Q+V + R L++ N+ + S L QEI L+ KL V R + EI
Sbjct: 523 VQEVAELR---RRLES-NKPAGDVDMS------LSLLQEISSLQEKL--EVTRTDHQREI 570
Query: 570 LAKKD-----QELEQQDKNSRGQA--RVIKIREELINVLKNKETEQSRELAALQQDLE 620
+ K+ +E Q++ + A ++ K E L + L++ E S +A + LE
Sbjct: 571 TSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLE 628
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 73.7 bits (173), Expect = 2e-12
Identities = 109/558 (19%), Positives = 240/558 (43%), Gaps = 41/558 (7%)
Query: 166 GDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV 225
G+ LS ++ +L + +L+ + E ++++ R ++ + +
Sbjct: 2101 GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLE 2160
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+L+ E + ++I + ++E E K +EEM L + ++ + Q++
Sbjct: 2161 RELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQ 2220
Query: 285 QTRNRVAKMDKQL----------REAEASITSLTGT-VKMLEDQSRQKEVQLEARARKLR 333
+ + +++++DK L +AE I + T V+ML++Q ++ + A +
Sbjct: 2221 EKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGD-Q 2279
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
E +K E + I++ L+ + + + ++E + +QQL+E + L+ +
Sbjct: 2280 EIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKES-EHHADLLKGRV 2338
Query: 394 EITKREIEL----KERTETELQDSRNAIEELQAKIIELEKSKPNPDLP-----TEREIDL 444
E +RE+E+ +E E ++S+ +E L+AKI + +S +L +E+E +L
Sbjct: 2339 ENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKE-NL 2397
Query: 445 WAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
ELQ KE R++E E+ E + K +Q+ + +Q Q +EL +
Sbjct: 2398 TNELQ--KEQERISELEIINSSFENILQEK---EQEKVQMKEKSSTAMEMLQTQLKELNE 2452
Query: 505 NIKL--NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ N+Q+ + ++ Q + Q G+ + + + L+ + ++
Sbjct: 2453 RVAALHNDQEACKAKEQNLSSQVECLELEKAQ-LLQGL--DEAKNNYIVLQSSVNGLIQE 2509
Query: 563 NEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
E+ + L KKD+E+ + + Q +++ + + EQ+ EL L +LE +
Sbjct: 2510 VEDGKQKLEKKDEEISRLKNQIQDQEQLVS-KLSQVEGEHQLWKEQNLELRNLTVELEQK 2568
Query: 623 MRIVDEVNKQIAAKADEIQELFATLEN-----KQQQIHRLEKIVLALXXXXXXXXXXXXX 677
++++ N + + +Q + LEN K ++ +EK V +
Sbjct: 2569 IQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VNKMTAKETELQREMHE 2627
Query: 678 XXXKIAALEHELAAGLNR 695
K A L+ EL+ NR
Sbjct: 2628 MAQKTAELQEELSGEKNR 2645
Score = 66.9 bits (156), Expect = 2e-10
Identities = 106/542 (19%), Positives = 232/542 (42%), Gaps = 36/542 (6%)
Query: 147 ENIIKYPKTNLTVNQD--QTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLS 204
E + + ++ T++Q+ Q + + L + + L L +L + + N + +
Sbjct: 398 EELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFK 457
Query: 205 KRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS-ESENTKA-LEEMRHEL 262
++ C + A + E+ + ++++ N ++ E ++ E + +A L+ ++ L
Sbjct: 458 QKLCRAEQAFQA-SQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCL 516
Query: 263 DEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--REAEASITSLTGTVKMLEDQSRQ 320
++ + +K K T+ E+ LR + ++ + + L + + ++ L +D ++
Sbjct: 517 NQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKK 576
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQR---DSLQAE--VLEC-KQQIEKLTVQHKSA 374
+E +E KL ++ K + S L ++ + L+ E + C K + EKL Q +S
Sbjct: 577 REHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESE 636
Query: 375 IQQLEEDLKQTKRALQEQCEITKREIELKERT-----ETELQDSRNAIEELQAKIIELEK 429
+ L+ + + L+ Q +I E + RT E + RN L +K +E+E
Sbjct: 637 KENLQSKINHLETCLKTQ-QIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVET 695
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE 489
K E+ AE K + + T + + E+ Q L+ E+++K+
Sbjct: 696 QKL-----AYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKD 750
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ-DLQQE 548
+ + L +K + ++ E + R L A ++ A N I Q + E
Sbjct: 751 RCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSE 810
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK-NSRGQAR---VIKIREELI-NVLKN 603
+ +++ + L + + LE Q + NS Q + +++I+ E+ N++K
Sbjct: 811 RSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKA 870
Query: 604 KETEQS------RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
++ QS + ++ LQ+D +V E + K E+Q L +E +Q +I L
Sbjct: 871 EQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQEL 930
Query: 658 EK 659
+K
Sbjct: 931 KK 932
Score = 65.3 bits (152), Expect = 7e-10
Identities = 82/403 (20%), Positives = 176/403 (43%), Gaps = 28/403 (6%)
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
L ++Q ++ RN++ +++ +L+ E + + L+ Q + +V+L + + L +
Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKC 339
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQ---QLEEDLKQTKRALQEQ 392
TT+Q Q A + K+ E L+ Q ++A LE+ +K+ ++ QE+
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEE 399
Query: 393 CEITKRE--------IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL 444
+R I++K R ELQ ++N LQA++ +L K + E
Sbjct: 400 LSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQK 459
Query: 445 WAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ + ++ E+E+ E + EN + L + K + ++ + +K
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNL-----LKSHSEQKAREVCHLEAE----LK 510
Query: 505 NIKLNEQKVIQYEQYVRDLQAHNRTIANC-QESPNGISYQDLQQEIMDLKMKLLDVVHRN 563
NIK Q + Q + + +++A N + ++ I+ Q+ + LK+ + D+ +
Sbjct: 511 NIK---QCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQR 567
Query: 564 EELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE-H 621
+ ++L K++ +EQ DK S+ + + L LK KE E+ +E L +
Sbjct: 568 DCSQDLLKKREHHIEQLNDKLSKTEKESKALLSAL--ELKKKEYEELKEEKTLFSCWKSE 625
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
+++ ++ + +I L L+ +Q + H + V L
Sbjct: 626 NEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTL 668
Score = 58.4 bits (135), Expect = 8e-08
Identities = 86/363 (23%), Positives = 158/363 (43%), Gaps = 29/363 (7%)
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
+ S+ S ++ DQS + L+ R L SL++ + S L +Q + L E
Sbjct: 804 QGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEI 863
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
++ + K H+S + + + + + + + + E E ELQ + +E
Sbjct: 864 EENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETE 923
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC----KRE-KESENKI 475
QA+I EL+KS + D ELQ ETL + + E+++ KRE +E +
Sbjct: 924 QAEIQELKKSNHLLE-------DSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 976
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G +++ A LN+E++ IQ E N +K I E + Q + C+E
Sbjct: 977 GTLKEINAS-LNQEKM---NLIQKSESFANYIDEREKSIS-ELSDQYKQEKLILLQRCEE 1031
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
+ N +Y+DL Q+ + K + E + + + ELEQ +A + +E
Sbjct: 1032 TGN--AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLK-----EAFAKEHQE 1084
Query: 596 ELINVLKNKETEQS--RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ 653
L + +E Q+ EL +QQ L R + D N ++A +++ TL+ +Q +
Sbjct: 1085 FLTKLAFAEERNQNLMLELETVQQAL--RSEMTDNQNNS-KSEAGGLKQEIMTLKEEQNK 1141
Query: 654 IHR 656
+ +
Sbjct: 1142 MQK 1144
Score = 57.2 bits (132), Expect = 2e-07
Identities = 83/436 (19%), Positives = 197/436 (45%), Gaps = 31/436 (7%)
Query: 248 ESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
E+EN+K +E ++ +++ + ++ + T S+ N + K +++ E E +S
Sbjct: 2358 EAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSS 2417
Query: 307 LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
++ E + Q + + L+ LK + L +++ +A+ Q+E
Sbjct: 2418 FENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVEC 2477
Query: 367 LTVQHKSAIQQLEED------LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
L ++ +Q L+E L+ + L ++ E K+++E K+ + L++ E+L
Sbjct: 2478 LELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQL 2537
Query: 421 QAKIIEL--------EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+K+ ++ E++ +L E E + LQ+ +L+ T + + + + E+E
Sbjct: 2538 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQV-LQSKNASLQDTLEVLQSSYKNLENE 2596
Query: 473 NKIGIQQKLA-AELLNKEEI-IGKMQIQTRELI-KNIKLNEQKVIQYEQYVRDLQAHNRT 529
++ K++ E +NK ++Q + E+ K +L E+ + + +LQ
Sbjct: 2597 LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEE 2656
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK---DQELEQQDKNSRG 586
I + ++ ++L E +LK K LD +H+++ E ++ + +L + +
Sbjct: 2657 IKSSKD-----QLKELTLENSELK-KSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 2710
Query: 587 QARVI---KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
QA ++ K E I + K T + L++ + +++ +E+N + A ++EL
Sbjct: 2711 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEEL 2770
Query: 644 FATLENKQQQIHRLEK 659
T + + +++L+K
Sbjct: 2771 KKTKMDNLKYVNQLKK 2786
Score = 51.6 bits (118), Expect = 9e-06
Identities = 87/430 (20%), Positives = 180/430 (41%), Gaps = 40/430 (9%)
Query: 257 EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED 316
E R E D+ ++ ++ + E L + + + KQ E + + E
Sbjct: 813 ECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQ 872
Query: 317 QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV--LECKQQIEKLTVQHKSA 374
+ + R KL+E + ++ + ++ + E+ L K + E+ +Q
Sbjct: 873 MHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKK 932
Query: 375 IQQLEEDLKQTKRALQEQCEITKRE----IELKERTETELQDSRNAIEELQAKIIE---- 426
L ED + + L E + K+E I L +R EL ++E+ A + +
Sbjct: 933 SNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMN 992
Query: 427 -LEKSKPNPDLPTEREIDLWAEL--QATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
++KS+ + ERE + +EL Q +E L + + C+ + + + K A
Sbjct: 993 LIQKSESFANYIDEREKSI-SELSDQYKQEKLILLQ----RCEETGNAYEDLSQKYKAAQ 1047
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
E +K E + + L +N K NE + ++ E + ++ Q +A +E + +
Sbjct: 1048 EKNSKLECLLN---ECTSLCENRK-NELEQLK-EAFAKEHQEFLTKLAFAEERNQNLMLE 1102
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL---EQQDKNSRGQARVIKIREELINV 600
L+ L+ ++ D ++N SE K + + E+Q+K + +++ E+L+ V
Sbjct: 1103 -LETVQQALRSEMTD--NQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKV 1159
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVN---------KQIAAKADEIQ--ELFATLEN 649
+K K Q+ E ++ ++ R ++ N K+I+ + Q +L A L N
Sbjct: 1160 MKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRN 1219
Query: 650 KQQQIHRLEK 659
K+ ++ EK
Sbjct: 1220 KELKLQESEK 1229
Score = 46.4 bits (105), Expect = 3e-04
Identities = 59/224 (26%), Positives = 104/224 (46%), Gaps = 31/224 (13%)
Query: 224 EVAKLRQDV----ETRNVMIDEIRELRSESENTKALEEMRHELD--EERTAKLAIKEKLT 277
E L+Q++ E +N M E+ +L E+E + + +HE E + ++KE+
Sbjct: 1124 EAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKER-- 1181
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRE 334
ES+ Q N +MD +++ E S+ S + LE R KE++L+ ++ L+
Sbjct: 1182 --ESERNQC-NFKPQMDLEVK--EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQH 1236
Query: 335 SLKT--GEVTTSQLIQQRDSLQAEVLECKQQIEK--LTVQHKSAIQQ-----LEEDLKQT 385
L+T G++ TS L + + + +C+ E+ ++ H+ + Q L+ L+ T
Sbjct: 1237 ELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTT 1296
Query: 386 KRALQEQ---CEITKREIELKERTETELQDSRNAIEELQAKIIE 426
L E CEI + E K TEL DSR+ K+ E
Sbjct: 1297 MNKLNELEKICEILQAE---KYELVTELNDSRSECITATRKMAE 1337
Score = 39.5 bits (88), Expect = 0.039
Identities = 57/298 (19%), Positives = 132/298 (44%), Gaps = 27/298 (9%)
Query: 134 ENALEL--LDETMPIENIIKYPKTNLTVNQD-----QTDGDILEHLSRYNDQGFELCGAL 186
EN LEL +D+ +E + K + ++ Q ++ E LS ++ L G L
Sbjct: 2594 ENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNR---LAGEL 2650
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE-- 244
+ L + + + + + +L+ +++L + + V + K+R+++ + + E +
Sbjct: 2651 QLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 2710
Query: 245 ----LRSESENTKALEEMRHELDEER----TAKLAIKEKLTTTESQLRQTRNRVAKMDKQ 296
L + + ++ R +L + + KL I + L +++ +L + ++ ++
Sbjct: 2711 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEI-DLLKSSKEELNNSLKATTQILEE 2769
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL-IQQRDSLQA 355
L++ + +K ++++ K L ++L E + + SQL Q
Sbjct: 2770 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTG 2829
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE--ITKREIE-LKERTETEL 410
V++ K +++LT + K + LEE K+ L + C I+ ++E KE ET++
Sbjct: 2830 TVMDTK--VDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQV 2885
Score = 37.1 bits (82), Expect = 0.21
Identities = 80/436 (18%), Positives = 188/436 (43%), Gaps = 29/436 (6%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTESQ 282
E +L +E R+ ++ + E ++ L+E++ E +L I +L S
Sbjct: 1782 ENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSD 1841
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG--- 339
L + + ++L + + L ++M D+S ++++ K+ +S K
Sbjct: 1842 LSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIG--DNVAKVNDSWKERFLD 1899
Query: 340 -EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-TK 397
E S++ ++ S++ E L + +E + + K +++ E+ ++ L+E+ + T
Sbjct: 1900 VENELSRIRSEKASIEHEALYLEADLEVVQTE-KLCLEKDNENKQKVIVCLEEELSVVTS 1958
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLR 456
+L+ +T + A+++L K+ E + + I + AE++ E L+
Sbjct: 1959 ERNQLRGELDT-MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQ 2017
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI-KLNEQKVIQ 515
+V+ ++K +Q+KL + L K+ + + EL I +LN++K
Sbjct: 2018 TLSSDVSELLKDKTH-----LQEKLQS--LEKDS--QALSLTKCELENQIAQLNKEK--- 2065
Query: 516 YEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI---LAK 572
E V++ ++ ++ +S + L+ +++ L + EE+ ++ + K
Sbjct: 2066 -ELLVKESESLQARLSESDYEKLNVS-KALEAALVEKGEFALRLSSTQEEVHQLRRGIEK 2123
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ 632
+E +K A +K RE + LK+K REL +++ E + + +
Sbjct: 2124 LRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAE 2183
Query: 633 IAAKADEIQELFATLE 648
+ +I+E+ +L+
Sbjct: 2184 VETLKTQIEEMARSLK 2199
Score = 36.7 bits (81), Expect = 0.28
Identities = 56/263 (21%), Positives = 119/263 (45%), Gaps = 13/263 (4%)
Query: 232 VETRNVMIDEIRELRSES-ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
VE N M + EL+ E E + E++ EL E+ +LA + +L E ++ +++++
Sbjct: 2608 VEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKN-RLAGELQLLLEE--IKSSKDQL 2664
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
++ + E + S+ + E + R++ + + R + + + + T++ +
Sbjct: 2665 KELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVE 2724
Query: 351 DSLQAEVLECKQQI---EKLTVQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
E L K++ +KL + KS+ ++L LK T + L+E + ++ +
Sbjct: 2725 IQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQL 2784
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTE-REIDLWAELQATKETLRVTEDEVTTC 465
+ E + ++ ++ L +LE+ K L E ++ E Q T + DE+TT
Sbjct: 2785 KKENERAQGKMKLLIKSCKQLEEEK--EILQKELSQLQAAQEKQKTGTVMDTKVDELTT- 2841
Query: 466 KREKESENKIGIQQKLAAELLNK 488
KE + + + K A E L+K
Sbjct: 2842 -EIKELKETLEEKTKEADEYLDK 2863
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 73.7 bits (173), Expect = 2e-12
Identities = 109/558 (19%), Positives = 240/558 (43%), Gaps = 41/558 (7%)
Query: 166 GDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREV 225
G+ LS ++ +L + +L+ + E ++++ R ++ + +
Sbjct: 2101 GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLE 2160
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+L+ E + ++I + ++E E K +EEM L + ++ + Q++
Sbjct: 2161 RELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQ 2220
Query: 285 QTRNRVAKMDKQL----------REAEASITSLTGT-VKMLEDQSRQKEVQLEARARKLR 333
+ + +++++DK L +AE I + T V+ML++Q ++ + A +
Sbjct: 2221 EKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGD-Q 2279
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
E +K E + I++ L+ + + + ++E + +QQL+E + L+ +
Sbjct: 2280 EIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKES-EHHADLLKGRV 2338
Query: 394 EITKREIEL----KERTETELQDSRNAIEELQAKIIELEKSKPNPDLP-----TEREIDL 444
E +RE+E+ +E E ++S+ +E L+AKI + +S +L +E+E +L
Sbjct: 2339 ENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKE-NL 2397
Query: 445 WAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
ELQ KE R++E E+ E + K +Q+ + +Q Q +EL +
Sbjct: 2398 TNELQ--KEQERISELEIINSSFENILQEK---EQEKVQMKEKSSTAMEMLQTQLKELNE 2452
Query: 505 NIKL--NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ N+Q+ + ++ Q + Q G+ + + + L+ + ++
Sbjct: 2453 RVAALHNDQEACKAKEQNLSSQVECLELEKAQ-LLQGL--DEAKNNYIVLQSSVNGLIQE 2509
Query: 563 NEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
E+ + L KKD+E+ + + Q +++ + + EQ+ EL L +LE +
Sbjct: 2510 VEDGKQKLEKKDEEISRLKNQIQDQEQLVS-KLSQVEGEHQLWKEQNLELRNLTVELEQK 2568
Query: 623 MRIVDEVNKQIAAKADEIQELFATLEN-----KQQQIHRLEKIVLALXXXXXXXXXXXXX 677
++++ N + + +Q + LEN K ++ +EK V +
Sbjct: 2569 IQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VNKMTAKETELQREMHE 2627
Query: 678 XXXKIAALEHELAAGLNR 695
K A L+ EL+ NR
Sbjct: 2628 MAQKTAELQEELSGEKNR 2645
Score = 66.9 bits (156), Expect = 2e-10
Identities = 106/542 (19%), Positives = 232/542 (42%), Gaps = 36/542 (6%)
Query: 147 ENIIKYPKTNLTVNQD--QTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLS 204
E + + ++ T++Q+ Q + + L + + L L +L + + N + +
Sbjct: 398 EELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFK 457
Query: 205 KRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS-ESENTKA-LEEMRHEL 262
++ C + A + E+ + ++++ N ++ E ++ E + +A L+ ++ L
Sbjct: 458 QKLCRAEQAFQA-SQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCL 516
Query: 263 DEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL--REAEASITSLTGTVKMLEDQSRQ 320
++ + +K K T+ E+ LR + ++ + + L + + ++ L +D ++
Sbjct: 517 NQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKK 576
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQR---DSLQAE--VLEC-KQQIEKLTVQHKSA 374
+E +E KL ++ K + S L ++ + L+ E + C K + EKL Q +S
Sbjct: 577 REHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESE 636
Query: 375 IQQLEEDLKQTKRALQEQCEITKREIELKERT-----ETELQDSRNAIEELQAKIIELEK 429
+ L+ + + L+ Q +I E + RT E + RN L +K +E+E
Sbjct: 637 KENLQSKINHLETCLKTQ-QIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVET 695
Query: 430 SKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE 489
K E+ AE K + + T + + E+ Q L+ E+++K+
Sbjct: 696 QKL-----AYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKD 750
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ-DLQQE 548
+ + L +K + ++ E + R L A ++ A N I Q + E
Sbjct: 751 RCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSE 810
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK-NSRGQAR---VIKIREELI-NVLKN 603
+ +++ + L + + LE Q + NS Q + +++I+ E+ N++K
Sbjct: 811 RSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKA 870
Query: 604 KETEQS------RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
++ QS + ++ LQ+D +V E + K E+Q L +E +Q +I L
Sbjct: 871 EQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQEL 930
Query: 658 EK 659
+K
Sbjct: 931 KK 932
Score = 65.3 bits (152), Expect = 7e-10
Identities = 82/403 (20%), Positives = 176/403 (43%), Gaps = 28/403 (6%)
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
L ++Q ++ RN++ +++ +L+ E + + L+ Q + +V+L + + L +
Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKC 339
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQ---QLEEDLKQTKRALQEQ 392
TT+Q Q A + K+ E L+ Q ++A LE+ +K+ ++ QE+
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEE 399
Query: 393 CEITKRE--------IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDL 444
+R I++K R ELQ ++N LQA++ +L K + E
Sbjct: 400 LSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQK 459
Query: 445 WAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ + ++ E+E+ E + EN + L + K + ++ + +K
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNL-----LKSHSEQKAREVCHLEAE----LK 510
Query: 505 NIKLNEQKVIQYEQYVRDLQAHNRTIANC-QESPNGISYQDLQQEIMDLKMKLLDVVHRN 563
NIK Q + Q + + +++A N + ++ I+ Q+ + LK+ + D+ +
Sbjct: 511 NIK---QCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQR 567
Query: 564 EELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE-H 621
+ ++L K++ +EQ DK S+ + + L LK KE E+ +E L +
Sbjct: 568 DCSQDLLKKREHHIEQLNDKLSKTEKESKALLSAL--ELKKKEYEELKEEKTLFSCWKSE 625
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
+++ ++ + +I L L+ +Q + H + V L
Sbjct: 626 NEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTL 668
Score = 58.4 bits (135), Expect = 8e-08
Identities = 86/363 (23%), Positives = 158/363 (43%), Gaps = 29/363 (7%)
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
+ S+ S ++ DQS + L+ R L SL++ + S L +Q + L E
Sbjct: 804 QGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEI 863
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
++ + K H+S + + + + + + + + E E ELQ + +E
Sbjct: 864 EENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETE 923
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC----KRE-KESENKI 475
QA+I EL+KS + D ELQ ETL + + E+++ KRE +E +
Sbjct: 924 QAEIQELKKSNHLLE-------DSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 976
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G +++ A LN+E++ IQ E N +K I E + Q + C+E
Sbjct: 977 GTLKEINAS-LNQEKM---NLIQKSESFANYIDEREKSIS-ELSDQYKQEKLILLQRCEE 1031
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
+ N +Y+DL Q+ + K + E + + + ELEQ +A + +E
Sbjct: 1032 TGN--AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLK-----EAFAKEHQE 1084
Query: 596 ELINVLKNKETEQS--RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ 653
L + +E Q+ EL +QQ L R + D N ++A +++ TL+ +Q +
Sbjct: 1085 FLTKLAFAEERNQNLMLELETVQQAL--RSEMTDNQNNS-KSEAGGLKQEIMTLKEEQNK 1141
Query: 654 IHR 656
+ +
Sbjct: 1142 MQK 1144
Score = 57.2 bits (132), Expect = 2e-07
Identities = 83/436 (19%), Positives = 197/436 (45%), Gaps = 31/436 (7%)
Query: 248 ESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
E+EN+K +E ++ +++ + ++ + T S+ N + K +++ E E +S
Sbjct: 2358 EAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSS 2417
Query: 307 LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
++ E + Q + + L+ LK + L +++ +A+ Q+E
Sbjct: 2418 FENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVEC 2477
Query: 367 LTVQHKSAIQQLEED------LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
L ++ +Q L+E L+ + L ++ E K+++E K+ + L++ E+L
Sbjct: 2478 LELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQL 2537
Query: 421 QAKIIEL--------EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+K+ ++ E++ +L E E + LQ+ +L+ T + + + + E+E
Sbjct: 2538 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQV-LQSKNASLQDTLEVLQSSYKNLENE 2596
Query: 473 NKIGIQQKLA-AELLNKEEI-IGKMQIQTRELI-KNIKLNEQKVIQYEQYVRDLQAHNRT 529
++ K++ E +NK ++Q + E+ K +L E+ + + +LQ
Sbjct: 2597 LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEE 2656
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK---DQELEQQDKNSRG 586
I + ++ ++L E +LK K LD +H+++ E ++ + +L + +
Sbjct: 2657 IKSSKD-----QLKELTLENSELK-KSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 2710
Query: 587 QARVI---KIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
QA ++ K E I + K T + L++ + +++ +E+N + A ++EL
Sbjct: 2711 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEEL 2770
Query: 644 FATLENKQQQIHRLEK 659
T + + +++L+K
Sbjct: 2771 KKTKMDNLKYVNQLKK 2786
Score = 51.6 bits (118), Expect = 9e-06
Identities = 87/430 (20%), Positives = 180/430 (41%), Gaps = 40/430 (9%)
Query: 257 EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED 316
E R E D+ ++ ++ + E L + + + KQ E + + E
Sbjct: 813 ECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQ 872
Query: 317 QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV--LECKQQIEKLTVQHKSA 374
+ + R KL+E + ++ + ++ + E+ L K + E+ +Q
Sbjct: 873 MHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKK 932
Query: 375 IQQLEEDLKQTKRALQEQCEITKRE----IELKERTETELQDSRNAIEELQAKIIE---- 426
L ED + + L E + K+E I L +R EL ++E+ A + +
Sbjct: 933 SNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMN 992
Query: 427 -LEKSKPNPDLPTEREIDLWAEL--QATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
++KS+ + ERE + +EL Q +E L + + C+ + + + K A
Sbjct: 993 LIQKSESFANYIDEREKSI-SELSDQYKQEKLILLQ----RCEETGNAYEDLSQKYKAAQ 1047
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
E +K E + + L +N K NE + ++ E + ++ Q +A +E + +
Sbjct: 1048 EKNSKLECLLN---ECTSLCENRK-NELEQLK-EAFAKEHQEFLTKLAFAEERNQNLMLE 1102
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL---EQQDKNSRGQARVIKIREELINV 600
L+ L+ ++ D ++N SE K + + E+Q+K + +++ E+L+ V
Sbjct: 1103 -LETVQQALRSEMTD--NQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKV 1159
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVN---------KQIAAKADEIQ--ELFATLEN 649
+K K Q+ E ++ ++ R ++ N K+I+ + Q +L A L N
Sbjct: 1160 MKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRN 1219
Query: 650 KQQQIHRLEK 659
K+ ++ EK
Sbjct: 1220 KELKLQESEK 1229
Score = 46.4 bits (105), Expect = 3e-04
Identities = 59/224 (26%), Positives = 104/224 (46%), Gaps = 31/224 (13%)
Query: 224 EVAKLRQDV----ETRNVMIDEIRELRSESENTKALEEMRHELD--EERTAKLAIKEKLT 277
E L+Q++ E +N M E+ +L E+E + + +HE E + ++KE+
Sbjct: 1124 EAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKER-- 1181
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRE 334
ES+ Q N +MD +++ E S+ S + LE R KE++L+ ++ L+
Sbjct: 1182 --ESERNQC-NFKPQMDLEVK--EISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQH 1236
Query: 335 SLKT--GEVTTSQLIQQRDSLQAEVLECKQQIEK--LTVQHKSAIQQ-----LEEDLKQT 385
L+T G++ TS L + + + +C+ E+ ++ H+ + Q L+ L+ T
Sbjct: 1237 ELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTT 1296
Query: 386 KRALQEQ---CEITKREIELKERTETELQDSRNAIEELQAKIIE 426
L E CEI + E K TEL DSR+ K+ E
Sbjct: 1297 MNKLNELEKICEILQAE---KYELVTELNDSRSECITATRKMAE 1337
Score = 39.5 bits (88), Expect = 0.039
Identities = 57/298 (19%), Positives = 132/298 (44%), Gaps = 27/298 (9%)
Query: 134 ENALEL--LDETMPIENIIKYPKTNLTVNQD-----QTDGDILEHLSRYNDQGFELCGAL 186
EN LEL +D+ +E + K + ++ Q ++ E LS ++ L G L
Sbjct: 2594 ENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNR---LAGEL 2650
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE-- 244
+ L + + + + + +L+ +++L + + V + K+R+++ + + E +
Sbjct: 2651 QLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 2710
Query: 245 ----LRSESENTKALEEMRHELDEER----TAKLAIKEKLTTTESQLRQTRNRVAKMDKQ 296
L + + ++ R +L + + KL I + L +++ +L + ++ ++
Sbjct: 2711 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEI-DLLKSSKEELNNSLKATTQILEE 2769
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL-IQQRDSLQA 355
L++ + +K ++++ K L ++L E + + SQL Q
Sbjct: 2770 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTG 2829
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE--ITKREIE-LKERTETEL 410
V++ K +++LT + K + LEE K+ L + C I+ ++E KE ET++
Sbjct: 2830 TVMDTK--VDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQV 2885
Score = 37.1 bits (82), Expect = 0.21
Identities = 80/436 (18%), Positives = 188/436 (43%), Gaps = 29/436 (6%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTESQ 282
E +L +E R+ ++ + E ++ L+E++ E +L I +L S
Sbjct: 1782 ENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSD 1841
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG--- 339
L + + ++L + + L ++M D+S ++++ K+ +S K
Sbjct: 1842 LSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIG--DNVAKVNDSWKERFLD 1899
Query: 340 -EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-TK 397
E S++ ++ S++ E L + +E + + K +++ E+ ++ L+E+ + T
Sbjct: 1900 VENELSRIRSEKASIEHEALYLEADLEVVQTE-KLCLEKDNENKQKVIVCLEEELSVVTS 1958
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLW-AELQATKETLR 456
+L+ +T + A+++L K+ E + + I + AE++ E L+
Sbjct: 1959 ERNQLRGELDT-MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQ 2017
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI-KLNEQKVIQ 515
+V+ ++K +Q+KL + L K+ + + EL I +LN++K
Sbjct: 2018 TLSSDVSELLKDKTH-----LQEKLQS--LEKDS--QALSLTKCELENQIAQLNKEK--- 2065
Query: 516 YEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI---LAK 572
E V++ ++ ++ +S + L+ +++ L + EE+ ++ + K
Sbjct: 2066 -ELLVKESESLQARLSESDYEKLNVS-KALEAALVEKGEFALRLSSTQEEVHQLRRGIEK 2123
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ 632
+E +K A +K RE + LK+K REL +++ E + + +
Sbjct: 2124 LRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAE 2183
Query: 633 IAAKADEIQELFATLE 648
+ +I+E+ +L+
Sbjct: 2184 VETLKTQIEEMARSLK 2199
Score = 36.7 bits (81), Expect = 0.28
Identities = 56/263 (21%), Positives = 119/263 (45%), Gaps = 13/263 (4%)
Query: 232 VETRNVMIDEIRELRSES-ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
VE N M + EL+ E E + E++ EL E+ +LA + +L E ++ +++++
Sbjct: 2608 VEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKN-RLAGELQLLLEE--IKSSKDQL 2664
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
++ + E + S+ + E + R++ + + R + + + + T++ +
Sbjct: 2665 KELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVE 2724
Query: 351 DSLQAEVLECKQQI---EKLTVQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
E L K++ +KL + KS+ ++L LK T + L+E + ++ +
Sbjct: 2725 IQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQL 2784
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTE-REIDLWAELQATKETLRVTEDEVTTC 465
+ E + ++ ++ L +LE+ K L E ++ E Q T + DE+TT
Sbjct: 2785 KKENERAQGKMKLLIKSCKQLEEEK--EILQKELSQLQAAQEKQKTGTVMDTKVDELTT- 2841
Query: 466 KREKESENKIGIQQKLAAELLNK 488
KE + + + K A E L+K
Sbjct: 2842 -EIKELKETLEEKTKEADEYLDK 2863
>AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens
cDNA FLJ43937 fis, clone TESTI4013924. ).
Length = 623
Score = 73.7 bits (173), Expect = 2e-12
Identities = 122/601 (20%), Positives = 262/601 (43%), Gaps = 50/601 (8%)
Query: 117 AQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYN 176
A +V L R+ + + L++LD I+N + + D ++ H
Sbjct: 35 ASQVENLTREL--ENGEKQQLQMLDRLKEIQNHFDTCEAERK-HADLQISELTRHAEDAT 91
Query: 177 DQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVET-- 234
Q L++ + E+A DL +A R + L R + K + V+
Sbjct: 92 KQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELT 151
Query: 235 --RNVMIDEIRELRSESENT-KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
N ++ E EL+++ + +E +R EL++ T + +E+L + E +LR ++ A
Sbjct: 152 GKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKLRDIKSHQA 211
Query: 292 KMDKQLREAEASITSLTGTVKM---LEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQ 348
++ +++ + +I L +K ++ Q + ++ LE +L++S + ++ +
Sbjct: 212 DLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQE 271
Query: 349 QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI-TKREIELKERTE 407
L A + ++ + K+ ++ L + Q K +E I T+ ++E ++ +
Sbjct: 272 SIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETATIITQLKLE-RDVHQ 330
Query: 408 TELQDSRNAIEELQAK----IIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDEV 462
EL+D ++++ ++ K I EL K E I L AE K ++ ++
Sbjct: 331 RELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAESLEEKNMAKIHRGQL 390
Query: 463 TTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
K + + + Q + + L + K Q++ RE K+I + E+ + + E+
Sbjct: 391 EKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEERE--KHISIEEEHLRRMEEARLQ 448
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDL------KMKLL----DV---VHR----NEE 565
L+ + QES G+ +++ K+K+ D+ HR ++
Sbjct: 449 LKDQLLCLETEQESILGVIGKEIDAACKTFSKDSVEKLKVFSSGPDIHYDPHRWLAESKT 508
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
+ L ++ +E E ++KN R Q ++ R++L N+ +NKE+E L L Q +E + ++
Sbjct: 509 KLQWLCEELKERENREKNLRHQ--LMLCRQQLRNLTENKESE----LQCLFQQIERQEQL 562
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAAL 685
+DE++++ K D ++E + K +++ L+ V+AL K++ L
Sbjct: 563 LDEIHRE---KRDLLEE----TQRKDEEMGSLQDRVIALETSTQVALDHLESVPEKLSLL 615
Query: 686 E 686
E
Sbjct: 616 E 616
Score = 57.2 bits (132), Expect = 2e-07
Identities = 86/417 (20%), Positives = 185/417 (44%), Gaps = 35/417 (8%)
Query: 258 MRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLED 316
M EL+E +R + KEK SQ+ + +KQ + + + E
Sbjct: 13 MASELEEVKRCMERKDKEKAHLA-SQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEA 71
Query: 317 QSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV--------LECKQQIEKLT 368
+ + ++Q+ R ++ K E S+L QQ ++L+ E L+ ++ I +
Sbjct: 72 ERKHADLQISELTRHAEDATKQAERYLSEL-QQSEALKEEAEKRREDLKLKAQESIRQWK 130
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
++HK + LE+ + + +I K + ELK + LQ N +EL + +
Sbjct: 131 LKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRA 190
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
+ E+ D+ + QA E L V T + E E + + IQ ++ E +
Sbjct: 191 LQEEELHSKEEKLRDIKSH-QADLE-LEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHL 248
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE 548
EE I EL K+ ++ K+++ ++ ++DL A +AN + + + + + ++
Sbjct: 249 EEEIA-------ELKKSQAQDKAKLLEMQESIKDLSAIRADLAN-KLAEEERAKKAVLKD 300
Query: 549 IMDLKMKLLDVVHRNEELSEILA--KKDQELEQQD-KNSRGQARVIKIR-----EELINV 600
+ DL + R+EE + I+ K ++++ Q++ K+ + +K + +EL+
Sbjct: 301 LSDLTAQ---AKSRDEETATIITQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKH 357
Query: 601 LKNKETEQSRELAALQ-QDLEHR--MRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
K +++E + L+ + LE + +I +++ ++ D + E EN+ +++
Sbjct: 358 FKKEKSEAENHIRTLKAESLEEKNMAKIHRGQLEKLKSQCDRLTEELTQNENENKKL 414
Score = 44.0 bits (99), Expect = 0.002
Identities = 72/298 (24%), Positives = 131/298 (43%), Gaps = 29/298 (9%)
Query: 375 IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNP 434
+++ E + K L Q E RE+E E+ + ++ D ++E+Q E + +
Sbjct: 20 VKRCMERKDKEKAHLASQVENLTRELENGEKQQLQMLDR---LKEIQNHFDTCEAERKHA 76
Query: 435 DLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGK 494
DL E+ AE ATK+ R E+ + KE K KL A+ E I +
Sbjct: 77 DLQIS-ELTRHAE-DATKQAERYLS-ELQQSEALKEEAEKRREDLKLKAQ-----ESIRQ 128
Query: 495 MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
+++ ++L E+ + + + V +L N I ++ Y LQQ I +L+
Sbjct: 129 WKLKHKKL-------ERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQ-IENLRK 180
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+L DV+ + E L K+++L + +K + I+ L+++ +QS+ +
Sbjct: 181 ELNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQ 240
Query: 615 LQQDLEHRMRIVDEVNK---QIAAKADEIQE-------LFATLENKQQQIHRLEKIVL 662
++ + H + E+ K Q AK E+QE + A L NK + R +K VL
Sbjct: 241 MKVEKAHLEEEIAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVL 298
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 73.3 bits (172), Expect = 3e-12
Identities = 100/488 (20%), Positives = 212/488 (43%), Gaps = 35/488 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 905 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLA 964
Query: 241 EIRELRSESEN-TKALEEMRHELDE----ERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++ + + +EN K L E LDE K A++E L+ ++V + K
Sbjct: 965 KVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSK 1024
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL----IQQRD 351
+ E + L G++ +Q ++ + LE RKL LK + + L +Q +
Sbjct: 1025 SKVKLEQQVDDLEGSL----EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
L+ + + QQ K+ + A+ QL++ LK+ + ++E E + E + + E
Sbjct: 1081 KLKKKEFDINQQNSKIEDEQALAL-QLQKKLKENQARIEELEEELEAERTARAKVEKLRS 1139
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREK 469
D +EE+ + LE++ + E AE Q + L + E T K
Sbjct: 1140 DLSRELEEISER---LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRK 1196
Query: 470 ESENKIGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAH 526
+ + + +L ++ N + + K++ + E + ++ N +++I+ + +L+
Sbjct: 1197 KHADSVA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKV 1250
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+RT+ + Q + + ++ Q+ + D + + N EL+ L +K+ + Q +RG
Sbjct: 1251 SRTLED-QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQL---TRG 1306
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFA 645
+ + E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + +
Sbjct: 1307 KLSYTQQMEDLKRQLE-EEGKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLS 1364
Query: 646 TLENKQQQ 653
++ Q
Sbjct: 1365 KANSEVAQ 1372
Score = 67.7 bits (158), Expect = 1e-10
Identities = 82/433 (18%), Positives = 189/433 (43%), Gaps = 32/433 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E IKE L +E++ ++ ++ + ++ +
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGR-------IKETLEKSEARRKELEEKMVSLLQEKNDL 889
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 949
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 950 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1009
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQ K+ L KSK + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1010 DDLQVEEDKVNSLSKSK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 1062
Query: 475 IGIQ--QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
+ + L + L EE + K + + I+ + +Q ++ +++ QA +
Sbjct: 1063 LTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEE 1122
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRGQ 587
E+ + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 1123 ELEAER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRRDL 1180
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATL 647
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ + +
Sbjct: 1181 EEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237
Query: 648 ENKQQQIHRLEKI 660
E + LEK+
Sbjct: 1238 EQIIKAKANLEKV 1250
Score = 62.9 bits (146), Expect = 4e-09
Identities = 98/451 (21%), Positives = 197/451 (43%), Gaps = 46/451 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESEN-TKALEEMRHELDEERTAKLAIKEK 275
V + L +E ++ + +++ +++I + ++ E ++ LE+ +E +
Sbjct: 1215 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLND 1274
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLT----GTVKMLEDQSRQKEVQLEARARK 331
TT ++L QT N ++ +QL E EA I+ LT + +ED RQ E + +A+
Sbjct: 1275 FTTQRAKL-QTEN--GELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK-NA 1330
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE 391
L +L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 1331 LAHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQR 1384
Query: 392 QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
E+ + + +L +R LQD+ A+E + AK LEK+K L E E DL +++ +
Sbjct: 1385 TEELEEAKKKLAQR----LQDAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERS 1437
Query: 452 KETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI-KLNE 510
+ +++ + +KI + K E E + Q + R L + KL
Sbjct: 1438 NAAAAALD-------KKQRNFDKILAEWKQKYEESQSE--LESSQKEARSLSTELFKLKN 1488
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNEELSE 568
YE+ + L+ R N QE + ++ Q + + + +L+ + EL
Sbjct: 1489 ----AYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQS 1544
Query: 569 ILAKKDQELEQQD-KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
L + + LE ++ K R Q +I+ E+ L K+ E ++Q + R+VD
Sbjct: 1545 ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE-------MEQAKRNHQRVVD 1597
Query: 628 EVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ + A+ E+ + + ++ +E
Sbjct: 1598 SLQTSLDAETRSRNEVLRVKKKMEGDLNEME 1628
Score = 59.3 bits (137), Expect = 5e-08
Identities = 96/470 (20%), Positives = 198/470 (42%), Gaps = 46/470 (9%)
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSE-----SENTKALEEMRHELDEERTAKLAIKEK 275
L ++ K D+ +N I++ + L + EN +EE+ EL+ ERTA+ +++
Sbjct: 1078 LEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKL 1137
Query: 276 LTTTESQLRQTRNRVAKM----DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
+ +L + R+ + Q+ + + LE+ + Q E A +K
Sbjct: 1138 RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1197
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE 391
+S+ L + + L+ E E K +++ +T + I+ + +L++ R L++
Sbjct: 1198 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKA-KANLEKVSRTLED 1256
Query: 392 QCEITKREIELKERT-----------ETELQDSRNAIEELQAKIIELEKSKPN-----PD 435
Q + ++E +R+ +TE + +EE +A I +L + K + D
Sbjct: 1257 QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMED 1316
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
L + E + A+ A L+ + + + E E + + + N E +
Sbjct: 1317 LKRQLEEEGKAK-NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1375
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ +T + + +L E K + Q ++D + + N + S + LQ EI DL
Sbjct: 1376 KYETDAIQRTEELEEAKK-KLAQRLQDAEEAVEAV-NAKCSSLEKTKHRLQNEIEDL--- 1430
Query: 556 LLDVVHRNEELSEILAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSR 610
++DV R+ + L KK + ++ + K Q+ + ++E ++ TE +
Sbjct: 1431 MVDV-ERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFK 1485
Query: 611 ELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
A ++ LEH + NK + +EI +L L + +H LEK+
Sbjct: 1486 LKNAYEESLEH-LETFKRENKNLQ---EEISDLTEQLGEGGKNVHELEKV 1531
Score = 56.0 bits (129), Expect = 4e-07
Identities = 116/557 (20%), Positives = 235/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL ++ + + + Y + E
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANL----EKVSRTLEDQANEYRVKLEE 1267
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
+L + TQ +L+ R E+ LI+ L R Q +E ++E
Sbjct: 1268 AQRSLNDFTTQRAKLQTENGELA-RQLEEKEALIS---QLTRGKLSYTQQMEDLKRQLEE 1323
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E ++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 1324 --EGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L++AE ++ ++ LE + + ++E L ++
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1437
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1438 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1497
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + E + ELEK + ++ +++L + L+ + +L
Sbjct: 1498 ETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEV---EKLELQSALEEAEASLE 1554
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAE-------LLNKEEIIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + N + ++ +Q + +N
Sbjct: 1555 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEV 1613
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1614 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1668
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 1669 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1728
Query: 612 LAALQQDLEHRMRIVDE 628
++ DL V+E
Sbjct: 1729 KKKMESDLTQLQSEVEE 1745
Score = 53.2 bits (122), Expect = 3e-06
Identities = 84/501 (16%), Positives = 206/501 (41%), Gaps = 30/501 (5%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1502
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + E+ ++R + E K ALEE L+ E L
Sbjct: 1503 ENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILR 1562
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1563 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVK-K 1618
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1677
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++++
Sbjct: 1678 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMES 1734
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
L+ E+ V C+ +E K + AE L KE+ T ++ +K N
Sbjct: 1735 DLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ-------DTSAHLERMKKN 1787
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
EQ ++DLQ Q L+ + +L+ +L RN E +
Sbjct: 1788 ------MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKG 1841
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEV 629
+ K ++ +++ + + + ++L++ L+ K R+ ++ + +V
Sbjct: 1842 MRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKV 1901
Query: 630 NKQIAAKADEIQELFATLENK 650
++ +A+E ++ + NK
Sbjct: 1902 QHEL-DEAEERADIAESQVNK 1921
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1638 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1696
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1697 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEK 1756
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1757 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1813
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1814 LQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKL 1873
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1874 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1925
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 73.3 bits (172), Expect = 3e-12
Identities = 91/436 (20%), Positives = 200/436 (45%), Gaps = 28/436 (6%)
Query: 236 NVMIDEIRELRSESENTKA-LE-EMRHELDEE--RTAKLAIKEKLTTTESQLRQTRNRVA 291
NV++ E+ +N +A L+ E+ E D E T + ++E+L E + + ++ +
Sbjct: 10 NVVLHELSGDDDTDQNMRAPLDPELHQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIR 69
Query: 292 KMDKQLREAEASIT----SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLI 347
+ D QL++ + ++ + +K L+ ++ K L +++ T T Q
Sbjct: 70 QKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSE 129
Query: 348 QQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLK----QTKRALQEQCEITKREIELK 403
+Q E + +IEK ++HK +Q+ EE + Q +A EQ + E+E
Sbjct: 130 EQLSKHDKSSTEEEMEIEK--IKHK--LQEKEELISTLQAQLTQAQAEQPAQSSTEMEEF 185
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
+ +LQ+ I LQA++ + + + + E++ +++ ++ L VT
Sbjct: 186 VMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELL---QLVT 242
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
E E + K+ + Q+ E ++E ++G+ Q+ L + + EQ+ Q ++ +
Sbjct: 243 QADVETEMQQKLRVLQRKLEE--HEESLVGRAQV-VDLLQQELTAAEQRNQILSQQLQQM 299
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELE-QQDK 582
+A + T+ N E+ S L++ +++ + L + EE+ +L + +Q + Q +
Sbjct: 300 EAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAEL 359
Query: 583 NSR----GQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
SR Q ++ E+ ++L ++T Q + +A + +++ + N+Q A
Sbjct: 360 ESRYSALEQKHKAEMEEKTSHILSLQKTGQELQ-SACDALKDQNSKLLQDKNEQAVQSAQ 418
Query: 639 EIQELFATLENKQQQI 654
IQ+L L+ K ++I
Sbjct: 419 TIQQLEDQLQQKSKEI 434
Score = 68.1 bits (159), Expect = 1e-10
Identities = 117/525 (22%), Positives = 246/525 (46%), Gaps = 52/525 (9%)
Query: 147 ENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKR 206
E++ N V++D + D + + + DQ E L E K + ++ T+ +
Sbjct: 1813 ESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLEN---- 1868
Query: 207 ACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-ALEEMRHELDEE 265
E+ TL++ E+ L+++V N++ +I+E S K EE + +L+E
Sbjct: 1869 ---EKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER 1925
Query: 266 RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ---KE 322
+LA E + + + + A++ +L E+E + +L V LE++ +Q ++
Sbjct: 1926 LMNQLA--ELNGSIGNYCQDVTD--AQIKNELLESE--MKNLKKCVSELEEEKQQLVKEK 1979
Query: 323 VQLEARARK-LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++E+ RK E ++ + ++ LQ E+L+ KQQ K + Q+
Sbjct: 1980 TKVESEIRKEYLEKIQGAQKEPGNKSHAKE-LQ-ELLKEKQQEVKQLQKDCIRYQEKISA 2037
Query: 382 LKQTKRALQEQCEITKREIEL-KERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
L++T +AL+ +++++E+ KE ++ + A EL + + L+ ++
Sbjct: 2038 LERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLAD 2097
Query: 441 EIDLWAELQATKETLR---VTEDEVTTCK----REKESENKIGIQQKLAA---ELLNKEE 490
+ L ELQ+ KE+++ +DE + EK + K +Q+KL A E ++ EE
Sbjct: 2098 NLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEE 2157
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
IG++Q+ + K ++ ++ + + V L A +++++ Q+ + + E
Sbjct: 2158 TIGEIQVTLNKKDKEVQQLQENL---DSTVTQLAAFTKSMSSLQDDRDRVI-----DEAK 2209
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR-EEL-INVLKNKETEQ 608
+ K D + EE EI K+D +D Q R + I EEL IN+ + + +Q
Sbjct: 2210 KWERKFSDAIQSKEE--EIRLKEDNCSVLKD-----QLRQMSIHMEELKINISRLEHDKQ 2262
Query: 609 SRELAALQQDLEHRMRIVDEV---NKQIAAKADEIQELFATLENK 650
E A Q +++ + ++ D + NK++ ++ +E + L+ + +N+
Sbjct: 2263 IWESKA-QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNE 2306
Score = 66.9 bits (156), Expect = 2e-10
Identities = 105/519 (20%), Positives = 227/519 (43%), Gaps = 49/519 (9%)
Query: 168 ILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAK 227
++E + D AL E + Q V ++ +++ ++ + + EA +
Sbjct: 724 LIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLD 783
Query: 228 LRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELD-------EERTAKLAIKEKLTTT 279
N++ ++I L E+++ +E +++ELD E+ T +++ +L
Sbjct: 784 YESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNK 843
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRE-SLKT 338
ES++ + RV + ++ E +++ + ++ +K+ +E + + E +
Sbjct: 844 ESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV 903
Query: 339 GEVTTS------QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED------LKQTK 386
E++ S QL +++ SL E+ K+Q+ L+ ++ +Q+EED LKQ
Sbjct: 904 TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNY 963
Query: 387 RALQEQCEITKREIE-----LKERTETELQDSRNAI---EELQAKIIELEKSKPNPDLPT 438
+ +I+K E++ LK+ E + + A+ +EL ++ LE+ N +
Sbjct: 964 DEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDES 1023
Query: 439 EREIDL----WAELQATKETLRVTEDEVTTCKREKE-------SENKIGIQ--QKLAAEL 485
++EI L E++ KE +E VT+ +E E SE ++ +Q +K E
Sbjct: 1024 KKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEK 1083
Query: 486 LNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQD 544
L EE + Q + +++ K N+ ++Q E + + QA + I + ++ +G S
Sbjct: 1084 LAAEEQFQALVKQMNQTLQD-KTNQIDLLQAE--ISENQAIIQKLITSNTDASDGDSVAL 1140
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK 604
+++ ++ H EL E + ++E EQ K + + R+ ++ + K
Sbjct: 1141 VKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQ---EALTSRKAILKKAQEK 1197
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
E EL + D DE +K+ D++++L
Sbjct: 1198 ERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1236
Score = 66.9 bits (156), Expect = 2e-10
Identities = 129/633 (20%), Positives = 280/633 (44%), Gaps = 57/633 (9%)
Query: 70 ELDRQAVLEVFQNLKSLYERLNNEGISACGE-GFLPQELILFNVADWTAQEVAQLYRDAI 128
E ++Q E Q L++ L ++ + GE L +E+ N+ + QE +L R
Sbjct: 1853 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQE--ELSRVTK 1910
Query: 129 ASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRE 188
T E + L+E + + + + + QD TD I L + + C + E
Sbjct: 1911 LKETAEEEKDDLEERL-MNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKC--VSE 1967
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE 248
L+ + + V T + R+ + + +E E + ++ ++ +E++
Sbjct: 1968 LEEEKQQLVKEKTKVESEI---RKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL 2024
Query: 249 SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLT 308
++ +E L ERT K A++ T ++ L T+ +A+ + ++A+A + S
Sbjct: 2025 QKDCIRYQEKISAL--ERTVK-ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASF- 2080
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTG-EVTTSQLIQQRDSLQA--EVLECKQQIE 365
K+L D ++ + ++ A KL++ L++ E SQ+ Q+ + L+ E E K E
Sbjct: 2081 ---KVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKE 2137
Query: 366 KLTVQHK-SAIQQ----LEEDL--------KQTKRA--LQEQCEITKREIELKERTETEL 410
K +Q K A+++ LEE + K+ K LQE + T ++ ++ + L
Sbjct: 2138 KKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL 2197
Query: 411 QDSRNAI----EELQAKIIELEKSKPNPDLPTEREI----DLWAELQATKETLRVTEDEV 462
QD R+ + ++ + K + +SK E D ++ E L++ +
Sbjct: 2198 QDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRL 2257
Query: 463 TTCKR--EKESENKIGIQQKLAAELLNK-EEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
K+ E +++ ++ +QQK+ L + +E++ +++ +TR L + + K+ +
Sbjct: 2258 EHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLE-ETRHLYHSSQNELAKLESELKS 2316
Query: 520 VRD-LQAHNRTIANCQESPNGISYQDLQQE--IMDLKMKLLDVVHRNEELSEILAKKDQE 576
++D L + ++ C+E + QQE I + K + + E+ ++ +E
Sbjct: 2317 LKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEE 2376
Query: 577 LEQQDKNSRGQARVIKIREELINV----LKNKETEQSRELAALQQDLEHRMRIVDEVNKQ 632
+ +++ ++ +EE I V L+ + ++ +EL L E +++E NK+
Sbjct: 2377 INMKEQKI---ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2433
Query: 633 IAAKADEIQELFATLENKQ-QQIHRLEKIVLAL 664
K +++ E T++ + QQ +L+ V ++
Sbjct: 2434 AVDKTNQLMETLKTIKKENIQQKAQLDSFVKSM 2466
Score = 66.9 bits (156), Expect = 2e-10
Identities = 107/526 (20%), Positives = 218/526 (41%), Gaps = 36/526 (6%)
Query: 161 QDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA 220
+ Q D +I E L Q E L E +A D N + + K E A ++
Sbjct: 2403 RQQHDKEIKE-LENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDS 2461
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTE 280
V+ ++ L+ D R+ ++ + ++L E + + E + E +KE++
Sbjct: 2462 FVKSMSSLQND---RDRIVGDYQQL--EERHLSIILEKDQLIQEAAAENNKLKEEIRGLR 2516
Query: 281 SQLRQTRNRVAKMDKQL----REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
S + + AK+D +L + IT K L + Q+ +LE + KL E L
Sbjct: 2517 SHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKL 2576
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEI 395
K E L + ++LQ E + ++IE L V +Q+ ++ T Q ++
Sbjct: 2577 KESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKV 2636
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ E+ R S+ I EL+ +++ ++K E E L EL+
Sbjct: 2637 KEEEV---HRLSALFSSSQKRIAELEEELVCVQKEAAKK--VGEIEDKLKKELKHLHHDA 2691
Query: 456 RVTEDEVTTCKRE--KESENKIGIQQKLAAELLNKEEIIGKMQ--------IQTRELIKN 505
+ +E T + + + + + ++QKL + + ++Q +Q N
Sbjct: 2692 GIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHAN 2751
Query: 506 IKLNEQKVIQYEQYVRDL-QAHNRTIANCQE----SPNGISYQDLQQEIMDLKMKL-LDV 559
+L+E K +Y+ +++L Q + + N + S S ++ + KL +
Sbjct: 2752 EELDELK-RKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQL 2810
Query: 560 VHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVL-KNKETEQSRELAALQQD 618
+ ++E+L + ++ + Q S+ A + R+ L N L K +++E+ ++ +A Q
Sbjct: 2811 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPS 2870
Query: 619 LEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
V + K +++ ++ L L+N QQQ ++ + + L
Sbjct: 2871 TSPAE--VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITEL 2914
Score = 62.9 bits (146), Expect = 4e-09
Identities = 87/456 (19%), Positives = 194/456 (42%), Gaps = 28/456 (6%)
Query: 219 EALVREVAKLRQD-VETRNVMIDEIRELRSESENT-KALEEMRHELDEERTAKLAIKEKL 276
E LV+E+ L+ + ++ +EL+ E E ++ E + +E + + A++++
Sbjct: 1584 EKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEK 1643
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
+LR T + +KQL+EAE + + ++ +QK ++LE +LR +
Sbjct: 1644 QELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEV 1703
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
T + ++ S A + K+++E++ +++++ ++ + L K +L E+ +
Sbjct: 1704 HPAGDTAKECMETLLSSNASM---KEELERVKMEYETLSKKF-QSLMSEKDSLSEEVQDL 1759
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
K +IE + L+ + + Q + E E ++ P E++ + E++
Sbjct: 1760 KHQIEDNVSKQANLEATEK--HDNQTNVTE-EGTQSIPGETEEQDSLSMSTRPTCSESVP 1816
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+ ++ S ++I + +L KE I G + E KN + ++ +
Sbjct: 1817 SAKSANPAVSKDFSSHDEINNYLQQIDQL--KERIAGLEE----EKQKNKEFSQTLENEK 1870
Query: 517 EQYVRDLQAHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEILAKKD 574
+ + + + QE ++ Q +Q+E+ + ++L E L +
Sbjct: 1871 NTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQL 1930
Query: 575 QELEQQDKNSRGQARVIKIREELI-NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI 633
EL N +I+ EL+ + +KN + S QQ ++ + ++ E+ K+
Sbjct: 1931 AELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1990
Query: 634 AAKADEIQ----------ELFATLENKQQQIHRLEK 659
K Q EL L+ KQQ++ +L+K
Sbjct: 1991 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2026
Score = 58.4 bits (135), Expect = 8e-08
Identities = 77/370 (20%), Positives = 159/370 (42%), Gaps = 17/370 (4%)
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
E+E + L ++ +L+E + + + + + +L R + +QL++ EA +L
Sbjct: 247 ETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTL 306
Query: 308 TGTVKMLEDQSR--QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
TV+ ++S+ ++++LE RKL S + L++Q + E + +
Sbjct: 307 RNTVETEREESKILLEKMELEVAERKL--SFHNLQEEMHHLLEQFEQAGQAQAELESRYS 364
Query: 366 KLTVQHKSAIQQLEE---DLKQTKRALQEQCEITKREIE--LKERTETELQDS---RNAI 417
L +HK+ +++ L++T + LQ C+ K + L+++ E +Q + +
Sbjct: 365 ALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLE 424
Query: 418 EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE-TLRVTEDEVTTC-KREKESENKI 475
++LQ K E+ + L + E T VTE+ + + KR E EN+
Sbjct: 425 DQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEK 484
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
G + EL + K+ Q L + E E + D+ N+ ++ +E
Sbjct: 485 GALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIA--NKRSSSAEE 542
Query: 536 SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI-LAKKDQELEQQDKNSRGQARVIKIR 594
S + Q+ +L + LL++ EE++ + L + + E+ D Q + ++
Sbjct: 543 SGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQME 602
Query: 595 EELINVLKNK 604
E I +K K
Sbjct: 603 GEGIAPIKMK 612
Score = 57.6 bits (133), Expect = 1e-07
Identities = 90/451 (19%), Positives = 192/451 (42%), Gaps = 43/451 (9%)
Query: 241 EIRELRSESENTKAL-EEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
E +EL S+ E T+ L ++EL + + ++K++LT + L + + + ++ +R+
Sbjct: 2285 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ 2344
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQ-QRDSLQAEVL 358
EA I + + + LE Q +L +R L E + E L+ + +++Q +
Sbjct: 2345 QEADIQNSKFSYEQLETDL-QASRELTSR---LHEEINMKEQKIISLLSGKEEAIQVAIA 2400
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIE 418
E +QQ H I++LE L Q + E K+ ++ + L+ +
Sbjct: 2401 ELRQQ-------HDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENI 2453
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEV---TTCKREKESENKI 475
+ +A++ KS + +R + + +L+ ++ + +D++ + K E
Sbjct: 2454 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIR 2513
Query: 476 GIQQ----------KLAAELLNKEE----IIGKMQIQTRELIK-NIKLNEQKVIQYEQYV 520
G++ KL AEL+ E +I Q ++L++ ++ N++ +Y +
Sbjct: 2514 GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLE 2573
Query: 521 RDLQAHNRTIANCQESPNGI--SYQDLQQEIMDLKMKLLDVVHRNEELSE---------I 569
L+ + + S N + QDL +EI LK+ + + + L E
Sbjct: 2574 EKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQ 2633
Query: 570 LAKKDQELEQQDK-NSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L K++E+ + S Q R+ ++ EEL+ V K + L+++L+H
Sbjct: 2634 LKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGI 2693
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ + + + EL L +Q++ + K
Sbjct: 2694 MRNETETAEERVAELARDLVEMEQKLLMVTK 2724
Score = 55.2 bits (127), Expect = 7e-07
Identities = 87/457 (19%), Positives = 196/457 (42%), Gaps = 31/457 (6%)
Query: 218 GEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLT 277
G V ++ +++E V + E++ + SE TK EE+ ++ L I+ T
Sbjct: 1300 GGTSVAQIKAQLKEIEAEKVEL-ELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKT 1358
Query: 278 TTESQLRQTRNRVAKMDK-QLREAEAS-ITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
+ + K++ QL+ A + L + L+ +KE + + +L E
Sbjct: 1359 VSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEK 1418
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE----------EDLKQT 385
+++I+Q D ++A Q+E +H I+QL+ E++ +
Sbjct: 1419 EAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEE 1474
Query: 386 KRALQE-----QCEITKREIELKER--TETELQDSRNAIEELQAKIIELEKSKPNPDLPT 438
RA Q+ Q + R+ LKE + EL +R IE L + ++E +
Sbjct: 1475 SRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEK 1534
Query: 439 EREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ-I 497
+ + A LQ ++ L +TE + + + + S + ++ L +KE+++ +++ +
Sbjct: 1535 DTVLGRLALLQEERDKL-ITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESL 1593
Query: 498 QTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLL 557
++ ++ ++ + E+ ++Y LQ++ ++N E + + ++QE +L KL
Sbjct: 1594 KSSKIAESTEWQEKHKELQKEYEILLQSY-ENVSNEAERIQHV-VEAVRQEKQELYGKLR 1651
Query: 558 DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ 617
+E + L + +QE+E+ + R + K +++ I L+ + E+
Sbjct: 1652 STEANKKETEKQLQEAEQEMEEMKEKMR---KFAKSKQQKILELEEENDRLRAEVHPAGD 1708
Query: 618 DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ M + N + + + ++ + TL K Q +
Sbjct: 1709 TAKECMETLLSSNASMKEELERVKMEYETLSKKFQSL 1745
Score = 50.8 bits (116), Expect = 2e-05
Identities = 87/449 (19%), Positives = 202/449 (44%), Gaps = 38/449 (8%)
Query: 219 EALVREVAKLRQDVETR-NVMIDEIRELRSESENTK-ALEEMRHE---LDEERT-----A 268
E ++E + +D+ N + +E ++L E E+ K ++ ++ + L EE T A
Sbjct: 2573 EEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHA 2632
Query: 269 KLAIKEKLTTTESQL-RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEA 327
+L +KE+ S L ++ R+A+++++L + G + ED+ +++ L
Sbjct: 2633 QLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEI---EDKLKKELKHLHH 2689
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
A +R +T E ++L + ++ ++L ++ + LT Q +S + + L+ ++
Sbjct: 2690 DAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSS-LQNSRD 2748
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAE 447
E+ + KR+ + + +L++ E A + E S + + E + +
Sbjct: 2749 HANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTE---ENSLSHLEK 2805
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK 507
L ++ L E + + ++S N++ K A L N+ + + + + K+ +
Sbjct: 2806 LN--QQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWN---ELEKFRKSEE 2860
Query: 508 LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS 567
++ Q ++Q+ + +++ Q + L +E+ +L+ + L + N+E++
Sbjct: 2861 GKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDR-----LLKELKNLQQQYLQI---NQEIT 2912
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR--- 624
E+ K Q E QDK Q ++R+E N+ E Q R + + E RM+
Sbjct: 2913 ELHPLKAQLQEYQDKTKAFQIMQEELRQE--NLSWQHELHQLRMEKSSWEIHERRMKEQY 2970
Query: 625 --IVDEVNKQIAAKADEIQELFATLENKQ 651
+ + ++Q++ + I+EL ++ Q
Sbjct: 2971 LMAISDKDQQLSHLQNLIRELRSSSSQTQ 2999
Score = 48.0 bits (109), Expect = 1e-04
Identities = 87/413 (21%), Positives = 180/413 (43%), Gaps = 40/413 (9%)
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLR----QTRNRVAKMDKQLREAEASITSLT 308
K E+++ +L E T++ AI +K E LR Q ++ ++ +Q E ++
Sbjct: 1171 KEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1230
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE-VLECKQQIEKL 367
++ L+ Q R+ + + + +ES + L + + + VLE +
Sbjct: 1231 DQLRQLQIQVRE-SIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWP 1289
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK-ERTETELQDSRNAIEELQAKIIE 426
+ ++ Q + Q K L+E E K E+ELK T +EL + +LQ +I
Sbjct: 1290 SHSEDASALQGGTSVAQIKAQLKE-IEAEKVELELKVSSTTSELTKKSEEVFQLQEQI-- 1346
Query: 427 LEKSKPNPDLPTEREIDLWAELQA--TKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+K ++ + + + AE+ A ++ L ++ ++ + +E + K+ QKL ++
Sbjct: 1347 ---NKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISK 1403
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQD 544
KEE + + Q E + + ++I+ E ++ L H + +E I +
Sbjct: 1404 ---KEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKAL--HTQLEMQAKEHDERI--KQ 1456
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK 604
LQ E+ ++K K EE+ E + +Q + QA +I +E L +NK
Sbjct: 1457 LQVELCEMKQK-------PEEIGE------ESRAKQQIQRKLQAALISRKEAL---KENK 1500
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
++ EL+ + +E + + +V Q++A+ E + L Q++ +L
Sbjct: 1501 SLQE--ELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKL 1551
Score = 45.6 bits (103), Expect = 6e-04
Identities = 75/395 (18%), Positives = 158/395 (40%), Gaps = 20/395 (5%)
Query: 68 QPELDRQAVLEVFQNLKSLYERL-----NNEGISACGEGFLPQELILFNVADWTAQEVAQ 122
+ E + V E+ ++L + ++L N+G++A + F L N D +E+ +
Sbjct: 2697 ETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2756
Query: 123 LYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFEL 182
L R AS L L E + + + + T+ + L HL + N Q
Sbjct: 2757 LKRKYDASL---KELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSK 2813
Query: 183 CGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEI 242
L L +Q ED+ N V SK +L + L E+ K R+ E +
Sbjct: 2814 DEQLLHLSSQLEDSYNQVQSFSKAMA----SLQNERDHLWNELEKFRKSEEGKQ---RSA 2866
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
+ + ++L++ L +R L + L Q+ Q + + QL+E +
Sbjct: 2867 AQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQ- 2925
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
T ++++++ RQ+ + + +LR + E+ ++ +Q ++ +
Sbjct: 2926 ---DKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLS 2982
Query: 363 QIEKLTVQHKSAIQQLEE-DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
++ L + +S+ Q + ++ ++A E L TE ++++E+
Sbjct: 2983 HLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIH 3042
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
K + +++ N E + L +L T ++LR
Sbjct: 3043 QKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLR 3077
Score = 44.8 bits (101), Expect = 0.001
Identities = 91/431 (21%), Positives = 188/431 (43%), Gaps = 33/431 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLR--EAEASITSL 307
EN +L++ EL+ E+ A L +L +++ + +++ ++ Q R EA+ ++ +
Sbjct: 468 ENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEI 527
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE-- 365
+ + D + ++ E + + E+ T SQ ++ L E+ E +++I
Sbjct: 528 S-----IVDIANKRSSSAEESGQDVLEN------TFSQKHKELSVLLLEMKEAQEEIAFL 576
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD-SRNAIEELQAKI 424
KL +Q K A + E L Q + E I I++K E QD EE
Sbjct: 577 KLQLQGKRAEEADHEVLDQKEMKQMEGEGIAP--IKMKVFLEDTGQDFPLMPNEESSLPA 634
Query: 425 IELEKSKPNPDLPTEREI---DLWAELQATKE----TLRVTEDEVTTCKREKESENKIGI 477
+E E++ T EI D EL++TK+ +L D + C +++ K I
Sbjct: 635 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPD-IGQCHQDELERLKSQI 693
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNI-KLNEQKVIQYEQYVRDLQAHNRTIANCQES 536
+ L +EI K + + I N+ +L E+ + A +
Sbjct: 694 LE-LELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQ 752
Query: 537 PNGISY-QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
+S +L+ ++ L+M L + + E D L +Q + +A+ ++
Sbjct: 753 VKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKI 812
Query: 596 ELI-NVLKNKE---TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E++ N L + + +EQS + +LQ L+++ V E +++ + +++EL L K+
Sbjct: 813 EVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 872
Query: 652 QQIHRLEKIVL 662
+I ++++++L
Sbjct: 873 LEITKMDQLLL 883
Score = 40.3 bits (90), Expect = 0.023
Identities = 87/452 (19%), Positives = 194/452 (42%), Gaps = 37/452 (8%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKA----LEEMRHELDEER-TAKLAIKE 274
+L + V +L + + E+ EL++E+E + LE + +R ++++I +
Sbjct: 472 SLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVD 531
Query: 275 KLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRE 334
S ++ V + + E S+ L +M E Q ++L+ + ++ E
Sbjct: 532 IANKRSSSAEESGQDVLENTFSQKHKELSVLLL----EMKEAQEEIAFLKLQLQGKRAEE 587
Query: 335 SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK------LTVQHKSAIQQLEEDLKQTKRA 388
+ EV + ++Q + ++ K +E L +S++ +E++ T+
Sbjct: 588 A--DHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQ 645
Query: 389 LQEQCEITKRE--IELKERTETELQDSRNAIEEL-QAKIIELEKSKPNPDLPTEREIDLW 445
+ EI+ + +ELK T+ + S +A+ ++ Q ELE+ K E E++
Sbjct: 646 SRTSEEISLNDAGVELKS-TKQDGDKSLSAVPDIGQCHQDELERLKSQI---LELELNFH 701
Query: 446 AELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
+ ++ L E++ + E K A L++E ++ Q +EL
Sbjct: 702 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEER--DQLLSQVKELSMV 759
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
+L Q V Q E + + + R Q + + + + + ++ K K + + E
Sbjct: 760 TELRAQ-VKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNE 818
Query: 566 LSEI-LAKKDQELEQQDKNSRGQARVIKIRE--ELINVLKNKETEQSRELAALQQDLEHR 622
L ++ L +Q + S+ Q + ++ E E + + +K E S+ L+ Q++LE
Sbjct: 819 LDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS--QKELE-- 874
Query: 623 MRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++++ + K +++ L T+E K QQ+
Sbjct: 875 ---ITKMDQLLLEKKRDVETLQQTIEEKDQQV 903
Score = 39.5 bits (88), Expect = 0.039
Identities = 88/469 (18%), Positives = 188/469 (40%), Gaps = 31/469 (6%)
Query: 210 ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE--LDEERT 267
E + L A ++ R ++ L+ + N +DE++ R + K L +++ + L+ ER
Sbjct: 2725 ENKGLTAQIQSFGRSMSSLQNSRDHANEELDELK--RKYDASLKELAQLKEQGLLNRERD 2782
Query: 268 AKLAIKE-KLTTTE----SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKE 322
A L+ + +TE S L + ++ D+QL + + V+ +
Sbjct: 2783 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQ 2842
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDL 382
+ + +L E + E + Q + AEV K+ + L +++L+
Sbjct: 2843 NERDHLWNEL-EKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQ 2901
Query: 383 KQTKRALQEQCEITKREIELKE---RTET-ELQDSRNAIEEL--QAKIIELEKSKPNPDL 436
+Q + QE E+ + +L+E +T+ ++ E L Q ++ +L K + ++
Sbjct: 2902 QQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEI 2961
Query: 437 PTEREIDLWAELQATKET-LRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
R + + + K+ L ++ + + + +Q + A G
Sbjct: 2962 HERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQ 3021
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLK 553
+ + +LN+ +++ +R +Q N + E N +S Q D Q + + +
Sbjct: 3022 NLVYETELLRTQLNDSLKEIHQKELR-IQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQ 3080
Query: 554 MKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRE-- 611
D+++ +L K+ QEL+ N +E V + + E+ RE
Sbjct: 3081 QHYGDLLNH----CAVLEKQVQELQAGPLNIDVAPGA---PQEKNGVHRKSDPEELREPQ 3133
Query: 612 --LAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ QQ L + + V+E+ K + + D+ L ++QI RLE
Sbjct: 3134 QSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRLE 3182
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 73.3 bits (172), Expect = 3e-12
Identities = 107/498 (21%), Positives = 220/498 (44%), Gaps = 43/498 (8%)
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
+L+ E + ++I + ++E E K +EEM L + ++ + Q+++
Sbjct: 65 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQE 124
Query: 286 TRNRVAKMDK-------QLRE---AEASITSLTGT-VKMLEDQSRQKEVQLEARARKLRE 334
+ +++++DK QL E AE I + T V+ML++Q ++ + A +E
Sbjct: 125 KQGQLSELDKLLSSFKSQLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGD-QE 183
Query: 335 SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
+K E + I++ L+ + + + ++E + +QQL+E + L+ + E
Sbjct: 184 IMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKES-EHHADLLKGRVE 242
Query: 395 ITKREIEL----KERTETELQDSRNAIEELQAKIIELEKSKPNPDLP-----TEREIDLW 445
+RE+E+ +E E ++S+ +E L+AKI + +S +L +E+E DL
Sbjct: 243 NLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKE-DLT 301
Query: 446 AELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
ELQ KE R++E E+ E +Q+K ++ KE+ M++ +L +
Sbjct: 302 NELQ--KEQERISELEIINSSFENI------LQEKEQEKVQMKEKSSTAMEMLQTQLKSS 353
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQ---EIMDLKMKLLDVVHR 562
++ Q I ++ V + + + C E Q L + + L+ + ++
Sbjct: 354 MR-EWQPCIMTKKPVSAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQE 412
Query: 563 NEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
E+ + L KKD+E+ + + Q +++ + + EQ+ EL L +LE +
Sbjct: 413 VEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQ-VEGEHQLWKEQNLELRNLTVELEQK 471
Query: 623 MRIVDEVNKQIAAKADEIQELFATLEN-----KQQQIHRLEKIVLALXXXXXXXXXXXXX 677
++++ N + + +Q + LEN K ++ +EK V +
Sbjct: 472 IQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VNKMTAKETELQREMHE 530
Query: 678 XXXKIAALEHELAAGLNR 695
K A L+ EL+ NR
Sbjct: 531 MAQKTAELQEELSGEKNR 548
Score = 60.5 bits (140), Expect = 2e-08
Identities = 79/410 (19%), Positives = 184/410 (44%), Gaps = 40/410 (9%)
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
+ +E++R ++ + +L I EKL + + +++V ++++L+ +E + +
Sbjct: 22 RGIEKLRVRIEADEKKQLHIAEKLKERDGENDSLKDKVENLERELQMSEEN-----QELV 76
Query: 313 MLEDQSRQKEVQ-LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
+L+ ++ + EV+ L+ + ++ SLK E+ L ++++L ++ E + Q+ +L
Sbjct: 77 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLL 136
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL---- 427
S QLEE +EQ EI ++KE ++T ++ +N ++EL + L
Sbjct: 137 SSFKSQLEE---------KEQAEI-----QIKEESKTAVEMLQNQLKELNEAVAALCGDQ 182
Query: 428 ---EKSKPNPDLPTEREIDLWAELQATKETLRVTE-DEVTTCKREKESENKIGIQQKLAA 483
+ ++ + D P E E L ++ + L E ++ ++ KESE+ + +
Sbjct: 183 EIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVE 242
Query: 484 ELLNKEEIIGKMQ----IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNG 539
L + EI Q ++ ++ + K+ Q +R L+ TI + +E
Sbjct: 243 NLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKE---- 298
Query: 540 ISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELIN 599
DL E+ + ++ ++ N IL +K+QE Q + S +++ + +
Sbjct: 299 ----DLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKSSM 354
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+ ++A +Q+L ++ ++ Q+ DE + + L++
Sbjct: 355 REWQPCIMTKKPVSAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQS 404
Score = 56.4 bits (130), Expect = 3e-07
Identities = 81/436 (18%), Positives = 195/436 (44%), Gaps = 31/436 (7%)
Query: 248 ESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
E+EN+K +E ++ +++ + ++ + T S+ N + K +++ E E +S
Sbjct: 261 EAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEIINSS 320
Query: 307 LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
++ E + Q + + L+ LK+ I + + A+ Q+E
Sbjct: 321 FENILQEKEQEKVQMKEKSSTAMEMLQTQLKSSMREWQPCIMTKKPVSAKEQNLSSQVEC 380
Query: 367 LTVQHKSAIQQLEED------LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
L ++ +Q L+E L+ + L ++ E K+++E K+ + L++ E+L
Sbjct: 381 LELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQL 440
Query: 421 QAKIIELE--------KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+K+ ++E ++ +L E E + LQ+ +L+ T + + + + E+E
Sbjct: 441 VSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQV-LQSKNASLQDTLEVLQSSYKNLENE 499
Query: 473 NKIGIQQKLA-AELLNKEEIIG-KMQIQTRELI-KNIKLNEQKVIQYEQYVRDLQAHNRT 529
++ K++ E +NK ++Q + E+ K +L E+ + + +LQ
Sbjct: 500 LELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEE 559
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKD---QELEQQDKNSRG 586
I + ++ ++L E +LK K LD +H+++ E +++ +L + +
Sbjct: 560 IKSSKDQ-----LKELTLENSELK-KSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 613
Query: 587 QARVIKIREEL---INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
QA ++ ++ I + K T + L++ + +++ +E+N + A ++EL
Sbjct: 614 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEEL 673
Query: 644 FATLENKQQQIHRLEK 659
T + + +++L+K
Sbjct: 674 KKTKMDNLKYVNQLKK 689
Score = 39.5 bits (88), Expect = 0.039
Identities = 57/298 (19%), Positives = 132/298 (44%), Gaps = 27/298 (9%)
Query: 134 ENALEL--LDETMPIENIIKYPKTNLTVNQD-----QTDGDILEHLSRYNDQGFELCGAL 186
EN LEL +D+ +E + K + ++ Q ++ E LS ++ L G L
Sbjct: 497 ENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNR---LAGEL 553
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE-- 244
+ L + + + + + +L+ +++L + + V + K+R+++ + + E +
Sbjct: 554 QLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKH 613
Query: 245 ----LRSESENTKALEEMRHELDEER----TAKLAIKEKLTTTESQLRQTRNRVAKMDKQ 296
L + + ++ R +L + + KL I + L +++ +L + ++ ++
Sbjct: 614 QALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEI-DLLKSSKEELNNSLKATTQILEE 672
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL-IQQRDSLQA 355
L++ + +K ++++ K L ++L E + + SQL Q
Sbjct: 673 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTG 732
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE--ITKREIE-LKERTETEL 410
V++ K +++LT + K + LEE K+ L + C I+ ++E KE ET++
Sbjct: 733 TVMDTK--VDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQV 788
Score = 36.7 bits (81), Expect = 0.28
Identities = 56/263 (21%), Positives = 119/263 (45%), Gaps = 13/263 (4%)
Query: 232 VETRNVMIDEIRELRSES-ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV 290
VE N M + EL+ E E + E++ EL E+ +LA + +L E ++ +++++
Sbjct: 511 VEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKN-RLAGELQLLLEE--IKSSKDQL 567
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
++ + E + S+ + E + R++ + + R + + + + T++ +
Sbjct: 568 KELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVE 627
Query: 351 DSLQAEVLECKQQI---EKLTVQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
E L K++ +KL + KS+ ++L LK T + L+E + ++ +
Sbjct: 628 IQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQL 687
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTE-REIDLWAELQATKETLRVTEDEVTTC 465
+ E + ++ ++ L +LE+ K L E ++ E Q T + DE+TT
Sbjct: 688 KKENERAQGKMKLLIKSCKQLEEEK--EILQKELSQLQAAQEKQKTGTVMDTKVDELTT- 744
Query: 466 KREKESENKIGIQQKLAAELLNK 488
KE + + + K A E L+K
Sbjct: 745 -EIKELKETLEEKTKEADEYLDK 766
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 73.3 bits (172), Expect = 3e-12
Identities = 85/437 (19%), Positives = 193/437 (44%), Gaps = 32/437 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E + IK++L +E++ ++ ++ + K+ +
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQK-------IKDELAKSEAKRKELEEKMVTLLKEKNDL 893
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 894 QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDEC 953
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + +
Sbjct: 954 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1013
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1014 DDLQAEEDKVNTLTKAK----IKLEQQVD---DLEGSLEQEKKLRMDLERAKRKLEGDLK 1066
Query: 475 IGIQ--QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
+ + + E +E + K + + L I+ + IQ ++ +++LQA +
Sbjct: 1067 LAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEE 1126
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-----SEILAKKDQELEQQDKNSRGQ 587
E+ S +++ DL +L ++ R EE ++I K +E E Q K R
Sbjct: 1127 EIEAERA-SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ-KMRRDL 1184
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATL 647
E L+ K + +A L + +++ R+ ++ K+ + EI +L + +
Sbjct: 1185 EEATLQHEATAATLRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNV 1241
Query: 648 ENKQQQIHRLEKIVLAL 664
E + LEK+ L
Sbjct: 1242 ETVSKAKGNLEKMCRTL 1258
Score = 72.9 bits (171), Expect = 3e-12
Identities = 103/500 (20%), Positives = 219/500 (43%), Gaps = 26/500 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 968
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 969 KVEKEKHATENKVKNLTEEMAGLD-ETIAKLT-KEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + + ++ L ++
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKL 1086
Query: 358 LECKQQIEKL--TVQHKSAIQ-QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ + +I L ++ + A+ QL++ +K+ + ++E E + E + + E + D
Sbjct: 1087 KKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1146
Query: 415 NAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKE-TLRVTEDEVTTCKREKESE 472
+EE+ ++ E + ++ +RE + + +E TL+ T K+ +S
Sbjct: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1206
Query: 473 NKIGIQQKLAAELLNK-EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
++G Q + K E+ +M+++ +L N++ + E+ R L+ +
Sbjct: 1207 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK 1266
Query: 532 NCQESP----NGISYQ--DLQQEI------MDLKMKLLDVVHRNEE-LSEILAKKDQELE 578
+ +E N ++ Q LQ E +D K L+ + R ++ ++ + + ++LE
Sbjct: 1267 SKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLE 1326
Query: 579 QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
++ K A ++ ++L+ + E+ A LQ+ L V + + + D
Sbjct: 1327 EEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY--ETD 1384
Query: 639 EIQELFATLENKQQQIHRLE 658
IQ E K++ RL+
Sbjct: 1385 AIQRTEELEEAKKKLAQRLQ 1404
Score = 64.1 bits (149), Expect = 2e-09
Identities = 90/452 (19%), Positives = 184/452 (40%), Gaps = 28/452 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEK 275
A+G L +++ +L+ +E I+ R R+++E ++ ++ EL+E ++E
Sbjct: 1105 ALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS--DLSRELEE---ISERLEEA 1159
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
T +Q+ + R A+ K R+ E + T L + +L + L+
Sbjct: 1160 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV 1219
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
+ E S++ + D L + V + + K + + LE+ L + K +EQ +
Sbjct: 1220 KQKLEKEKSEMKMEIDDLASNV----ETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRL 1275
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKET 454
+ R +TE + ++E +A + +L + K E + L E++A
Sbjct: 1276 INDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNAL 1335
Query: 455 LRVTEDEVTTC-----KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ C + E+E E+K +Q+ L+ N E + + +T + + +L
Sbjct: 1336 AHALQSSRHDCDLLREQYEEEQESKAELQRALSKA--NTEVAQWRTKYETDAIQRTEELE 1393
Query: 510 EQKVIQYEQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E K + Q ++ + H + A C + Q LQ E+ DL +LDV E +
Sbjct: 1394 EAKK-KLAQRLQAAEEHVEAVNAKCASLEK--TKQRLQNEVEDL---MLDV----ERTNA 1443
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
A D++ DK + + + + + EL ++ E + ++
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
+ ++ EI +L + ++IH LEKI
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1535
Score = 56.4 bits (130), Expect = 3e-07
Identities = 91/486 (18%), Positives = 205/486 (42%), Gaps = 41/486 (8%)
Query: 188 ELKTQAEDAVNTVTDLSK------RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
EL+ ++A + T+L K + + TL + L +E++ L + + I E
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 1531
Query: 242 IRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ +++ + E K E++ L+E + + K+ + +L Q ++ V D+++ E +
Sbjct: 1532 LEKIKKQVEQEKC--ELQAALEEAEASLEHEEGKILRIQLELNQVKSEV---DRKIAEKD 1586
Query: 302 ASITSLTGT-VKMLEDQSRQKEVQLEARARKLRESLKT-GEVTTSQL-IQQRDSLQAEVL 358
I L ++++E + ++ +R +R K G++ ++ + + + AE L
Sbjct: 1587 EEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEAL 1646
Query: 359 EC---KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
Q I K T H + +EDLK+ ++ + + + EIE T + + SR
Sbjct: 1647 RNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRK 1706
Query: 416 AIEE--LQA-KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
E+ L A + ++L ++ + T+++++ ++ + + ED + + +E
Sbjct: 1707 IAEQELLDASERVQLLHTQNTSLINTKKKLE--TDISQMQGEM---EDILQEARNAEEKA 1761
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
K + AE L KE+ T ++ +K N EQ V+DLQ
Sbjct: 1762 KKAITDAAMMAEELKKEQ-------DTSAHLERMKKN------MEQTVKDLQLRLDEAEQ 1808
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK 592
Q L+ + +L+ ++ RN E + L K ++ +++ + + I
Sbjct: 1809 LALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNIL 1868
Query: 593 IREELINVLKNKETEQSRELAALQQDLE---HRMRIVDEVNKQIAAKADEIQELFATLEN 649
++L++ L+ K R+ ++ + R + ++ +AD + L
Sbjct: 1869 RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRV 1928
Query: 650 KQQQIH 655
K +++H
Sbjct: 1929 KSREVH 1934
Score = 55.2 bits (127), Expect = 7e-07
Identities = 72/405 (17%), Positives = 176/405 (43%), Gaps = 17/405 (4%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
D + EL + +N L+ ++ +L++E++ + L + + + + + KM + L +
Sbjct: 1204 DSVAELGEQIDN---LQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ + S + L + + +L+ + + L E SQL + + + ++ E
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
K+Q+E+ ++ K+A+ + + L+EQ E E E K + L + + +
Sbjct: 1321 LKRQLEE-EIKAKNALAHALQSSRHDCDLLREQYE---EEQESKAELQRALSKANTEVAQ 1376
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES-ENKIGIQ 478
+ K E + + +L E + L LQA +E + + + ++ K+ +N++
Sbjct: 1377 WRTK-YETDAIQRTEEL-EEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV--- 1431
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
+ L ++ + + R K + +QK + + Q R++ +
Sbjct: 1432 EDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGT-ELFKI 1490
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
+Y++ ++ LK + ++ +L+E +A+ + + + +K + +V + + EL
Sbjct: 1491 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK---QVEQEKCELQ 1547
Query: 599 NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
L+ E E + + ++ EV+++IA K +EI +L
Sbjct: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQL 1592
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 112/258 (43%), Gaps = 19/258 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV-ETRNVMI 239
EL L + + + A + D S+R + L +L+ KL D+ + + M
Sbjct: 1693 ELRATLEQTERSRKIAEQELLDASERV----QLLHTQNTSLINTKKKLETDISQMQGEME 1748
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
D ++E R+ E K + D A+ KE+ T+ + + D QLR
Sbjct: 1749 DILQEARNAEEKAK-----KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Query: 300 AEASITSLTG---TVKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSL 353
EA +L G ++ LE + R+ E ++E+ ++ E++K E +L Q +
Sbjct: 1804 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED 1863
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER---TETEL 410
+ +L + ++KL + KS +Q EE +Q+ L + ++ E +ER E+++
Sbjct: 1864 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
Query: 411 QDSRNAIEELQAKIIELE 428
R E+ K+I E
Sbjct: 1924 NKLRVKSREVHTKVISEE 1941
>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1454
Score = 73.3 bits (172), Expect = 3e-12
Identities = 86/425 (20%), Positives = 196/425 (46%), Gaps = 33/425 (7%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV-REVAKLRQDVETRNVMIDEIRE 244
L + KT+ E N V +L K H T + EAL REV + E +N +
Sbjct: 908 LDQTKTELEKKTNAVKELEKLQ-HSTETELT--EALQKREVL----ETELQNAHGELKST 960
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
LR E L++ + L+E+ T + +L + ++ + + +MD+ L+E +
Sbjct: 961 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL 1020
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
V L+ R+ ++E + KL +L+ E+ + +Q +SL ++ K+Q+
Sbjct: 1021 KQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQL 1080
Query: 365 ---EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
E + +Q++ I QL++++++T++ ++E + K E ++ T+ +++ + +EL+
Sbjct: 1081 REKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMK---EQEQYIATQYKEAIDLGQELR 1137
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE--DEVTTCKREKESENKIGIQQ 479
+++ S + +L R ++QA +E R++ +++ +EK++ + +
Sbjct: 1138 LTREQVQNS--HTELAEARH----QQVQAQREIERLSSELEDMKQLSKEKDAHGN-HLAE 1190
Query: 480 KLAAELLNKEEIIGKMQIQTREL---IKNIK--LNEQKVIQYEQYVR-----DLQAHNRT 529
+L A + + + +MQ + ++L ++++K + + + E + + D Q +
Sbjct: 1191 ELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQ 1250
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQAR 589
N Q + ++ Q + +L ++ D E +E L K+ EL + G +
Sbjct: 1251 QLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEK 1310
Query: 590 VIKIR 594
I+
Sbjct: 1311 AEDIK 1315
Score = 66.1 bits (154), Expect = 4e-10
Identities = 83/449 (18%), Positives = 200/449 (44%), Gaps = 27/449 (6%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
++V +L + +D+ +E S+ E K + ++ + + + + L T+++
Sbjct: 857 QKVIELTGTARQVKIEMDQYKEELSKME--KEIMHLKRDGENKAMHLSQLDMILDQTKTE 914
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTG 339
L + N V +++K E +T ++LE + + +L++ R+L R+ L+
Sbjct: 915 LEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKA 974
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC-EITKR 398
+++ + L AE+ ECK +IE K + ++++ LK+ L+++ ++T
Sbjct: 975 QLSLEEKYTTIKDLTAELRECKMEIE----DKKQELLEMDQALKERNWELKQRAAQVTHL 1030
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
++ ++E E++ +E K ELE + N + + + A+ Q ++ +
Sbjct: 1031 DMTIREH-RGEMEQKIIKLEGTLEKS-ELELKECNKQIESLNDKLQNAKEQLREKEFIML 1088
Query: 459 EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ 518
++E + +KE E +++ + + +E+ I + +L + ++L ++V
Sbjct: 1089 QNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQV--QNS 1146
Query: 519 YVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEELSEILAKKDQEL 577
+ +A ++ + +E + L E+ D+K + H N E+ A K +E
Sbjct: 1147 HTELAEARHQQVQAQRE------IERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREA 1200
Query: 578 EQQDKNSRGQARVIKIREELINVLKNKETEQ---SRELAALQQDLEHRMRIVDEVNKQIA 634
+ +R QA + K+ E+ ++ + E A + + + V ++N+Q+
Sbjct: 1201 HLE---ARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLE 1257
Query: 635 AKADEIQELFATLENKQQQIHRLEKIVLA 663
E++E T+ N QQ+ +++ A
Sbjct: 1258 KAKLELEEAQDTVSNLHQQVQDRNEVIEA 1286
Score = 64.1 bits (149), Expect = 2e-09
Identities = 87/418 (20%), Positives = 181/418 (43%), Gaps = 43/418 (10%)
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLR----EAEASITSLT 308
+ L E + E+ +E K E L ++Q+ + +V ++D L E + L
Sbjct: 691 RLLTESKGEMKKENMKK---DEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLE 747
Query: 309 GTVKMLEDQSRQK-------EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL--- 358
G + E Q ++K + +L+ + L+E+ + + L QQ+ LQ E +
Sbjct: 748 GNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNG 807
Query: 359 ---ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
+ + ++EK + + +Q+ E + R ++E+CE E +LK + EL +
Sbjct: 808 ELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTAR 867
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
++ IE+++ K E+EI + + + + +++ ++ + + E E K
Sbjct: 868 QVK------IEMDQYKEELS-KMEKEI-MHLKRDGENKAMHLSQLDMILDQTKTELEKKT 919
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
++L +L + E +Q RE+++ N + + +R LQ + Q
Sbjct: 920 NAVKEL-EKLQHSTETELTEALQKREVLETELQNAHG--ELKSTLRQLQELRDVLQKAQL 976
Query: 536 S--PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
S + +DL E+ + KM++ D E+ + L +++ EL+Q+ A+V
Sbjct: 977 SLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQR------AAQV--- 1027
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
L ++ E +++ L+ LE + E NKQI + D++Q L K+
Sbjct: 1028 -THLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKE 1084
Score = 61.3 bits (142), Expect = 1e-08
Identities = 86/501 (17%), Positives = 209/501 (41%), Gaps = 29/501 (5%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSES------ENTK---ALEEMRHELDEERTAKLAIK 273
+ ++ L+QD+ + ++ + L +ES EN K AL+ +++++ EE +
Sbjct: 670 KTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLD 729
Query: 274 EKLTTTESQL----RQTRNRVAKMDKQLREAEASITSLTGTVKMLE---DQSRQKEVQLE 326
L + +L Q K +KQL++ + L +K+ ++ ++ V L+
Sbjct: 730 SALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQ 789
Query: 327 ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK 386
++ ++ L+ + +L + L+ +V + +Q+++K Q +S+ ++L + ++ +
Sbjct: 790 HTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQK---QRESSAEKLRKMEEKCE 846
Query: 387 RALQEQCEITKREIELK---ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
A E ++ IEL + + E+ + + +++ +I+ L++ N + ++D
Sbjct: 847 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLS-QLD 905
Query: 444 LWAELQAT---KETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
+ + T K+T V E E E E + ++ L EL N + Q +
Sbjct: 906 MILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQ 965
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA-NCQESPNGISYQD--LQQEIMDLKMKLL 557
EL ++ + + + ++DL A R ++ + D L++ +LK +
Sbjct: 966 ELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAA 1025
Query: 558 DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ 617
V H + + E + +Q++ + + +K + I L +K +L +
Sbjct: 1026 QVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEF 1085
Query: 618 DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXX 677
+ + + ++ K+I ++E+ + ++ ++Q I K + L
Sbjct: 1086 IMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQN 1145
Query: 678 XXXKIAALEHELAAGLNRKER 698
++A H+ ER
Sbjct: 1146 SHTELAEARHQQVQAQREIER 1166
Score = 58.8 bits (136), Expect = 6e-08
Identities = 89/486 (18%), Positives = 203/486 (41%), Gaps = 30/486 (6%)
Query: 194 EDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK 253
+ + ++ + + + L+ +L+ + + ++ + + + ++ +
Sbjct: 110 DQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVP 169
Query: 254 ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
LEE L+ E +A+ + L E++L Q++ V + ++ L+E++ L +
Sbjct: 170 ILEEQIINLEAEVSAQDKV---LREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLE 226
Query: 314 LEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE--VLE-----CKQQIEK 366
Q ++ E Q E K + ++ ++ + +QAE +LE C+++ ++
Sbjct: 227 QTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKR 286
Query: 367 LTVQ---HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
L + +KS ++ L+E L+Q K E + +L +SR +I +L+++
Sbjct: 287 LQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESE 346
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
+ ++ + +L + A E L + + E+ + + E S KI Q L
Sbjct: 347 LENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKR 406
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLN---EQKVIQYEQYVR------DLQAHNRTIANCQ 534
EL + + K Q+ + ++ + K++ E ++ ++Q + + Q
Sbjct: 407 ELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQ 466
Query: 535 ESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKI 593
S + I+ D Q+ K+ L+ ++ + KDQ +K + + R++
Sbjct: 467 LSQSLITCNDSQESS---KLSSLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTG 523
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ 653
EEL L E E S L+ ++ HR + +++ KA +L + + K Q
Sbjct: 524 IEELRTKLIQIEAENSD----LKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQ 579
Query: 654 IHRLEK 659
+ LEK
Sbjct: 580 LLTLEK 585
Score = 44.0 bits (99), Expect = 0.002
Identities = 73/310 (23%), Positives = 143/310 (46%), Gaps = 40/310 (12%)
Query: 375 IQQLEEDLKQTKRALQEQCEITKREIELK--ERTETELQDSRNAIEELQAKIIELEKSKP 432
I+ L E L + ++ Q C +T+ + E EL SR + L++ ++
Sbjct: 113 IKSLREKLNKLRQ--QNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESA----QQQAA 166
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR---EKESENKIGIQQ--KLAAELLN 487
+ + E+ I+L AE+ A + LR E+++ ++ EKE + ++ KL +LL
Sbjct: 167 SVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLE 226
Query: 488 KEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD----LQAHN----RTIANCQESPNG 539
+ + + + Q E + N + + QY++ V + +QA R + NC++
Sbjct: 227 QTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKR 286
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRN---EELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + + E+ LK KL + N +E I+A K+ E+ Q SR ++K+
Sbjct: 287 LQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQS--ILKLE 344
Query: 595 EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
EL +NK+ E R+ +L E+R E+ ++AA+ + + +E+ + ++
Sbjct: 345 SEL----ENKD-EILRDKFSLMN--ENR-----ELKVRVAAQNERLDLCQQEIESSRVEL 392
Query: 655 HRLEKIVLAL 664
LEKI+ L
Sbjct: 393 RSLEKIISQL 402
Score = 43.2 bits (97), Expect = 0.003
Identities = 83/425 (19%), Positives = 173/425 (40%), Gaps = 37/425 (8%)
Query: 242 IRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
I +L SE EN + + L E +K ++ +L + + +LR E
Sbjct: 340 ILKLESELENKDEILRDKFSLMNENRE---LKVRVAAQNERLDLCQQEIESSRVELRSLE 396
Query: 302 ASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECK 361
I+ L ++ +S + Q+ + + K + E + + R L + E +
Sbjct: 397 KIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQ 456
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK---REIE---------LKERTETE 409
+ LT S D +++ + + E K ++E + ++ E E
Sbjct: 457 KLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVESVKDQNQHTMNKQYEKE 516
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREK 469
Q IEEL+ K+I++E N DL ++ Q +E L E + K E
Sbjct: 517 RQRLVTGIEELRTKLIQIEAE--NSDLKVNMA-HRTSQFQLIQEEL--LEKASNSSKLES 571
Query: 470 ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRT 529
E K Q L E +E+I+ I KN +L EQ++++ + +R L+ T
Sbjct: 572 EMTKKCS--QLLTLEKQLEEKIVAYSSIAA----KNAEL-EQELMEKNEKIRSLE----T 620
Query: 530 IANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQAR 589
N + ++++ ++ ++ ++ + R L L KKDQ+ ++Q+K +
Sbjct: 621 NINTEHEKICLAFEKAKKIHLEQHKEMEKQIER---LEAQLEKKDQQFKEQEKTMSMLQQ 677
Query: 590 VIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
I ++ + L TE E+ + ++ + Q++ + ++++L + LE
Sbjct: 678 DIICKQHHLESLDRLLTESKGEMKKENMKKDEALK---ALQNQVSEETIKVRQLDSALEI 734
Query: 650 KQQQI 654
++++
Sbjct: 735 CKEEL 739
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 73.3 bits (172), Expect = 3e-12
Identities = 85/437 (19%), Positives = 193/437 (44%), Gaps = 32/437 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E + IK++L +E++ ++ ++ + K+ +
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQK-------IKDELAKSEAKRKELEEKMVTLLKEKNDL 893
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E + E ++L ++ L+ E
Sbjct: 894 QLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDEC 953
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + +
Sbjct: 954 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL 1013
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1014 DDLQAEEDKVNTLTKAK----IKLEQQVD---DLEGSLEQEKKLRMDLERAKRKLEGDLK 1066
Query: 475 IGIQ--QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
+ + + E +E + K + + L I+ + IQ ++ +++LQA +
Sbjct: 1067 LAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEE 1126
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-----SEILAKKDQELEQQDKNSRGQ 587
E+ S +++ DL +L ++ R EE ++I K +E E Q K R
Sbjct: 1127 EIEAERA-SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ-KMRRDL 1184
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATL 647
E L+ K + +A L + +++ R+ ++ K+ + EI +L + +
Sbjct: 1185 EEATLQHEATAATLRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNV 1241
Query: 648 ENKQQQIHRLEKIVLAL 664
E + LEK+ L
Sbjct: 1242 ETVSKAKGNLEKMCRTL 1258
Score = 72.9 bits (171), Expect = 3e-12
Identities = 103/500 (20%), Positives = 219/500 (43%), Gaps = 26/500 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E + VT+ ++ L A L E ++L++D++ + +
Sbjct: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 968
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 969 KVEKEKHATENKVKNLTEEMAGLD-ETIAKLT-KEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + + ++ L ++
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKL 1086
Query: 358 LECKQQIEKL--TVQHKSAIQ-QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ + +I L ++ + A+ QL++ +K+ + ++E E + E + + E + D
Sbjct: 1087 KKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1146
Query: 415 NAIEELQAKIIEL-EKSKPNPDLPTEREIDLWAELQATKE-TLRVTEDEVTTCKREKESE 472
+EE+ ++ E + ++ +RE + + +E TL+ T K+ +S
Sbjct: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSV 1206
Query: 473 NKIGIQQKLAAELLNK-EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
++G Q + K E+ +M+++ +L N++ + E+ R L+ +
Sbjct: 1207 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELK 1266
Query: 532 NCQESP----NGISYQ--DLQQEI------MDLKMKLLDVVHRNEE-LSEILAKKDQELE 578
+ +E N ++ Q LQ E +D K L+ + R ++ ++ + + ++LE
Sbjct: 1267 SKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLE 1326
Query: 579 QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
++ K A ++ ++L+ + E+ A LQ+ L V + + + D
Sbjct: 1327 EEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY--ETD 1384
Query: 639 EIQELFATLENKQQQIHRLE 658
IQ E K++ RL+
Sbjct: 1385 AIQRTEELEEAKKKLAQRLQ 1404
Score = 64.1 bits (149), Expect = 2e-09
Identities = 90/452 (19%), Positives = 184/452 (40%), Gaps = 28/452 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEK 275
A+G L +++ +L+ +E I+ R R+++E ++ ++ EL+E ++E
Sbjct: 1105 ALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS--DLSRELEE---ISERLEEA 1159
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
T +Q+ + R A+ K R+ E + T L + +L + L+
Sbjct: 1160 GGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV 1219
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEI 395
+ E S++ + D L + V + + K + + LE+ L + K +EQ +
Sbjct: 1220 KQKLEKEKSEMKMEIDDLASNV----ETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRL 1275
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER-EIDLWAELQATKET 454
+ R +TE + ++E +A + +L + K E + L E++A
Sbjct: 1276 INDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNAL 1335
Query: 455 LRVTEDEVTTC-----KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
+ C + E+E E+K +Q+ L+ N E + + +T + + +L
Sbjct: 1336 AHALQSSRHDCDLLREQYEEEQESKAELQRALSKA--NTEVAQWRTKYETDAIQRTEELE 1393
Query: 510 EQKVIQYEQYVRDLQAHNRTI-ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E K + Q ++ + H + A C + Q LQ E+ DL +LDV E +
Sbjct: 1394 EAKK-KLAQRLQAAEEHVEAVNAKCASLEK--TKQRLQNEVEDL---MLDV----ERTNA 1443
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
A D++ DK + + + + + EL ++ E + ++
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
+ ++ EI +L + ++IH LEKI
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKI 1535
Score = 56.4 bits (130), Expect = 3e-07
Identities = 91/486 (18%), Positives = 205/486 (42%), Gaps = 41/486 (8%)
Query: 188 ELKTQAEDAVNTVTDLSK------RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
EL+ ++A + T+L K + + TL + L +E++ L + + I E
Sbjct: 1472 ELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 1531
Query: 242 IRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
+ +++ + E K E++ L+E + + K+ + +L Q ++ V D+++ E +
Sbjct: 1532 LEKIKKQVEQEKC--ELQAALEEAEASLEHEEGKILRIQLELNQVKSEV---DRKIAEKD 1586
Query: 302 ASITSLTGT-VKMLEDQSRQKEVQLEARARKLRESLKT-GEVTTSQL-IQQRDSLQAEVL 358
I L ++++E + ++ +R +R K G++ ++ + + + AE L
Sbjct: 1587 EEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEAL 1646
Query: 359 EC---KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
Q I K T H + +EDLK+ ++ + + + EIE T + + SR
Sbjct: 1647 RNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRK 1706
Query: 416 AIEE--LQA-KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
E+ L A + ++L ++ + T+++++ ++ + + ED + + +E
Sbjct: 1707 IAEQELLDASERVQLLHTQNTSLINTKKKLE--TDISQMQGEM---EDILQEARNAEEKA 1761
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
K + AE L KE+ T ++ +K N EQ V+DLQ
Sbjct: 1762 KKAITDAAMMAEELKKEQ-------DTSAHLERMKKN------MEQTVKDLQLRLDEAEQ 1808
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK 592
Q L+ + +L+ ++ RN E + L K ++ +++ + + I
Sbjct: 1809 LALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNIL 1868
Query: 593 IREELINVLKNKETEQSRELAALQQDLE---HRMRIVDEVNKQIAAKADEIQELFATLEN 649
++L++ L+ K R+ ++ + R + ++ +AD + L
Sbjct: 1869 RLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRV 1928
Query: 650 KQQQIH 655
K +++H
Sbjct: 1929 KSREVH 1934
Score = 55.2 bits (127), Expect = 7e-07
Identities = 72/405 (17%), Positives = 176/405 (43%), Gaps = 17/405 (4%)
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
D + EL + +N L+ ++ +L++E++ + L + + + + + KM + L +
Sbjct: 1204 DSVAELGEQIDN---LQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ + S + L + + +L+ + + L E SQL + + + ++ E
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
K+Q+E+ ++ K+A+ + + L+EQ E E E K + L + + +
Sbjct: 1321 LKRQLEE-EIKAKNALAHALQSSRHDCDLLREQYE---EEQESKAELQRALSKANTEVAQ 1376
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES-ENKIGIQ 478
+ K E + + +L E + L LQA +E + + + ++ K+ +N++
Sbjct: 1377 WRTK-YETDAIQRTEEL-EEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEV--- 1431
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
+ L ++ + + R K + +QK + + Q R++ +
Sbjct: 1432 EDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGT-ELFKI 1490
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
+Y++ ++ LK + ++ +L+E +A+ + + + +K + +V + + EL
Sbjct: 1491 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK---QVEQEKCELQ 1547
Query: 599 NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
L+ E E + + ++ EV+++IA K +EI +L
Sbjct: 1548 AALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQL 1592
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 112/258 (43%), Gaps = 19/258 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV-ETRNVMI 239
EL L + + + A + D S+R + L +L+ KL D+ + + M
Sbjct: 1693 ELRATLEQTERSRKIAEQELLDASERV----QLLHTQNTSLINTKKKLETDISQMQGEME 1748
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
D ++E R+ E K + D A+ KE+ T+ + + D QLR
Sbjct: 1749 DILQEARNAEEKAK-----KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Query: 300 AEASITSLTG---TVKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSL 353
EA +L G ++ LE + R+ E ++E+ ++ E++K E +L Q +
Sbjct: 1804 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED 1863
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER---TETEL 410
+ +L + ++KL + KS +Q EE +Q+ L + ++ E +ER E+++
Sbjct: 1864 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV 1923
Query: 411 QDSRNAIEELQAKIIELE 428
R E+ K+I E
Sbjct: 1924 NKLRVKSREVHTKVISEE 1941
>L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein.
Length = 1300
Score = 72.9 bits (171), Expect = 3e-12
Identities = 107/497 (21%), Positives = 214/497 (43%), Gaps = 27/497 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAK---LRQDVETRNV 237
E G L++ + Q ++A T L + R V + + A+ +QD++++ V
Sbjct: 464 EKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV 523
Query: 238 MID-EIRELRSESENT----KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
+ E++ L S+ +T + LE+ +L E ++ +E L + + +
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTGEVTTSQLIQQ 349
+Q A+ TS + + L +K+ Q++ L R+ L + E +
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM 643
Query: 350 RDSLQAEVLECKQQI-EKLTVQHKSAIQQLEEDLKQTK-RALQEQCEITKREIELKERTE 407
L+AEV + + E+ H+ Q +K K R L+EQ + EI K
Sbjct: 644 NFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQ---HEISNKMEEF 700
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
L D A++ K+ L +PN D+ + E + + + K + E +
Sbjct: 701 KILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVAT 760
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK-LNEQKVIQYEQYVRDLQAH 526
++E N I + + + + Q+ L++ +K + +K + + L+A
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEELSEILAKKDQELEQQDKNSR 585
+AN +++ QDL+QEI LK ++ +V + + ++LS + K QEL+ K
Sbjct: 821 LLKVANKEKT-----VQDLKQEIKALKEEIGNVQLEKAQQLS--ITSKVQELQNLLKGKE 873
Query: 586 GQARVIK-IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
Q +K + EE L N + ++L + L+ ++ V + N + A+ A + +EL
Sbjct: 874 EQMNTMKAVLEEKEKDLANTG-KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELE 932
Query: 645 ATLENKQQQIHRLEKIV 661
L+ K+ ++ RLE ++
Sbjct: 933 IVLKEKENELKRLEAML 949
Score = 63.7 bits (148), Expect = 2e-09
Identities = 108/506 (21%), Positives = 227/506 (44%), Gaps = 37/506 (7%)
Query: 170 EHLSRYNDQGFELCGALRELKTQAEDAVN--TVTDLSKRACHERRTLI-AVGEALVREVA 226
E L+ + L +++LK + D V+ ++ + K+ HE+ I +V E L E+
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELL 822
Query: 227 KLRQDVETRNVMIDEIRELRSESENT---KALE-EMRHELDEERTAKLAIKEKLTTTESQ 282
K+ +T + EI+ L+ E N KA + + ++ E + +E++ T ++
Sbjct: 823 KVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAV 882
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVT 342
L + +A K L++ + SL V+ + Q KE ++ +L LK E
Sbjct: 883 LEEKEKDLANTGKWLQDLQEENESLKAHVQEVA-QHNLKEASSASQFEELEIVLKEKENE 941
Query: 343 TSQL---IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKRE 399
+L +++R+S + + Q ++ KS I+QL++ Q + E+ K
Sbjct: 942 LKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLK-- 999
Query: 400 IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
+ ER E E+ N ++ L+ +E ++ K N +++++ EL+A KE L+
Sbjct: 1000 -VISER-EKEISGLWNELDSLK-DAVEHQRKKNNE---RQQQVEA-VELEA-KEVLKKLF 1051
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
+V+ E G ++K A E + ++++ +L + +++ ++ E+Y
Sbjct: 1052 PKVSVPSNLSYGEWLHGFEKK-AKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKY 1110
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRN-EELSEILAKKDQELE 578
L + Q S ++QE K+K+ D H+ +++ +QELE
Sbjct: 1111 KSVLAETEGILQKLQRS--------VEQEENKWKVKV-DESHKTIKQMQSSFTSSEQELE 1161
Query: 579 QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
+ ++ + + RE L L+ E E+S + + ++L+ ++ +E ++ + +
Sbjct: 1162 RLRSENKDIENLRREREHLEMELEKAEMERSTYVTEV-RELKAQL---NETLTKLRTEQN 1217
Query: 639 EIQELFATLENKQQQIHRLE-KIVLA 663
E Q++ L QQ + ++ KIV A
Sbjct: 1218 ERQKVAGDLHKAQQSLELIQSKIVKA 1243
Score = 60.5 bits (140), Expect = 2e-08
Identities = 84/454 (18%), Positives = 200/454 (44%), Gaps = 36/454 (7%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKA----------LEEMRHELDEERTAKLAI 272
REV L + + + ++L++E++ A L+ M DE +
Sbjct: 249 REVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLL 308
Query: 273 KEKLTTTESQLRQT-RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
KEK + L+++ + + + QL+E + + ++ +D+ +Q ++ +
Sbjct: 309 KEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKER 368
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED---LKQTKRA 388
+ + L ++ + Q ++ Q+ +++ ++ + +Q+E + LKQ
Sbjct: 369 SNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGI 428
Query: 389 LQEQCEITKREIELKERTETEL--QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
L++ T ++E K+ E QD + EL K +L++ + + L
Sbjct: 429 LRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKV 488
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
+LQ + +EV + R++ +E++ QQ L ++ + KE + + + + + +
Sbjct: 489 QLQEAERRW----EEVQSYIRKRTAEHEAA-QQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 507 KLNEQKVIQY----EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ EQ+++Q ++ V ++ + + E + Q +QQ + + V
Sbjct: 544 QQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQ-IQQFHSQIAAQTSASVLA 602
Query: 563 NEELSEILAKKDQELEQ-QDKNSRGQARVIKIREEL-----INVLKNKETEQSRELAALQ 616
EEL +++A+KD++++Q +D + + R+ EEL +N L E ++ + LA Q
Sbjct: 603 -EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQ 661
Query: 617 QDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
H + +++ + + K D+I+ L L+++
Sbjct: 662 AAAAHEL---EKMQQSVYVKDDKIRLLEEQLQHE 692
Score = 59.3 bits (137), Expect = 5e-08
Identities = 118/558 (21%), Positives = 243/558 (43%), Gaps = 40/558 (7%)
Query: 122 QLYRDAIASSTPENAL--ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQG 179
Q + IA+ T + L EL + IK + +L +D+ E L +
Sbjct: 586 QQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKE-EELKDIQNMN 644
Query: 180 FELCGALRELKTQAEDAVNTVTDLSK--RACHERRTLIAVGEALVREVAKLRQDVETRNV 237
F L +++L+ A + +L K ++ + + I + E ++ ++ +E +
Sbjct: 645 FLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH--EISNKMEEFKI 702
Query: 238 MIDEIRELRSESENTKAL--EEMRHELDEERTAKLAIK-EKLTTTESQLRQTRNRVAKMD 294
+ D+ + L+SE + + L E+ ++ E+ + K EKL T E L +VA +
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKE 762
Query: 295 KQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL--KTGEVTTSQLIQQRDS 352
++L +SLT V+ L+ + +V + +L++ + K G++ + + +
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQND-QVSFASLVEELKKVIHEKDGKIKSVE-----EL 816
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE--RTETEL 410
L+AE+L+ + EK K I+ L+E++ + +Q IT + EL+ + + E
Sbjct: 817 LEAELLKVANK-EKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQ 875
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT-----KETLRVTE-DEVTT 464
++ A+ E + K + K DL E E L A +Q KE ++ +E+
Sbjct: 876 MNTMKAVLEEKEKDLA-NTGKWLQDLQEENE-SLKAHVQEVAQHNLKEASSASQFEELEI 933
Query: 465 CKREKESENKI--GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
+EKE+E K + ++ ++L +K +++ +Q + + L K+ ++ + K Y+Q
Sbjct: 934 VLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENK-LFKS-QIEQLKQQNYQQ-ASS 990
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
H + E IS L E+ LK + +N E + + + E ++ K
Sbjct: 991 FPPHEELLKVISEREKEIS--GLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLK 1048
Query: 583 NSRGQARV---IKIREELINVLKN-KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
+ V + E L K KE + + LEH+++ DE++ + + +
Sbjct: 1049 KLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECE 1108
Query: 639 EIQELFATLENKQQQIHR 656
+ + + A E Q++ R
Sbjct: 1109 KYKSVLAETEGILQKLQR 1126
>D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein.
Length = 1307
Score = 72.9 bits (171), Expect = 3e-12
Identities = 107/497 (21%), Positives = 214/497 (43%), Gaps = 27/497 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAK---LRQDVETRNV 237
E G L++ + Q ++A T L + R V + + A+ +QD++++ V
Sbjct: 471 EKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV 530
Query: 238 MID-EIRELRSESENT----KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
+ E++ L S+ +T + LE+ +L E ++ +E L + + +
Sbjct: 531 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 590
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTGEVTTSQLIQQ 349
+Q A+ TS + + L +K+ Q++ L R+ L + E +
Sbjct: 591 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM 650
Query: 350 RDSLQAEVLECKQQI-EKLTVQHKSAIQQLEEDLKQTK-RALQEQCEITKREIELKERTE 407
L+AEV + + E+ H+ Q +K K R L+EQ + EI K
Sbjct: 651 NFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQ---HEISNKMEEF 707
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
L D A++ K+ L +PN D+ + E + + + K + E +
Sbjct: 708 KILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVAT 767
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK-LNEQKVIQYEQYVRDLQAH 526
++E N I + + + + Q+ L++ +K + +K + + L+A
Sbjct: 768 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 827
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEELSEILAKKDQELEQQDKNSR 585
+AN +++ QDL+QEI LK ++ +V + + ++LS + K QEL+ K
Sbjct: 828 LLKVANKEKT-----VQDLKQEIKALKEEIGNVQLEKAQQLS--ITSKVQELQNLLKGKE 880
Query: 586 GQARVIK-IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
Q +K + EE L N + ++L + L+ ++ V + N + A+ A + +EL
Sbjct: 881 EQMNTMKAVLEEKEKDLANTG-KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELE 939
Query: 645 ATLENKQQQIHRLEKIV 661
L+ K+ ++ RLE ++
Sbjct: 940 IVLKEKENELKRLEAML 956
Score = 63.7 bits (148), Expect = 2e-09
Identities = 108/506 (21%), Positives = 227/506 (44%), Gaps = 37/506 (7%)
Query: 170 EHLSRYNDQGFELCGALRELKTQAEDAVN--TVTDLSKRACHERRTLI-AVGEALVREVA 226
E L+ + L +++LK + D V+ ++ + K+ HE+ I +V E L E+
Sbjct: 770 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELL 829
Query: 227 KLRQDVETRNVMIDEIRELRSESENT---KALE-EMRHELDEERTAKLAIKEKLTTTESQ 282
K+ +T + EI+ L+ E N KA + + ++ E + +E++ T ++
Sbjct: 830 KVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAV 889
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVT 342
L + +A K L++ + SL V+ + Q KE ++ +L LK E
Sbjct: 890 LEEKEKDLANTGKWLQDLQEENESLKAHVQEVA-QHNLKEASSASQFEELEIVLKEKENE 948
Query: 343 TSQL---IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKRE 399
+L +++R+S + + Q ++ KS I+QL++ Q + E+ K
Sbjct: 949 LKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLK-- 1006
Query: 400 IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
+ ER E E+ N ++ L+ +E ++ K N +++++ EL+A KE L+
Sbjct: 1007 -VISER-EKEISGLWNELDSLK-DAVEHQRKKNNE---RQQQVEA-VELEA-KEVLKKLF 1058
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
+V+ E G ++K A E + ++++ +L + +++ ++ E+Y
Sbjct: 1059 PKVSVPSNLSYGEWLHGFEKK-AKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKY 1117
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRN-EELSEILAKKDQELE 578
L + Q S ++QE K+K+ D H+ +++ +QELE
Sbjct: 1118 KSVLAETEGILQKLQRS--------VEQEENKWKVKV-DESHKTIKQMQSSFTSSEQELE 1168
Query: 579 QQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
+ ++ + + RE L L+ E E+S + + ++L+ ++ +E ++ + +
Sbjct: 1169 RLRSENKDIENLRREREHLEMELEKAEMERSTYVTEV-RELKAQL---NETLTKLRTEQN 1224
Query: 639 EIQELFATLENKQQQIHRLE-KIVLA 663
E Q++ L QQ + ++ KIV A
Sbjct: 1225 ERQKVAGDLHKAQQSLELIQSKIVKA 1250
Score = 60.5 bits (140), Expect = 2e-08
Identities = 84/454 (18%), Positives = 200/454 (44%), Gaps = 36/454 (7%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKA----------LEEMRHELDEERTAKLAI 272
REV L + + + ++L++E++ A L+ M DE +
Sbjct: 256 REVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLL 315
Query: 273 KEKLTTTESQLRQT-RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
KEK + L+++ + + + QL+E + + ++ +D+ +Q ++ +
Sbjct: 316 KEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKER 375
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED---LKQTKRA 388
+ + L ++ + Q ++ Q+ +++ ++ + +Q+E + LKQ
Sbjct: 376 SNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGI 435
Query: 389 LQEQCEITKREIELKERTETEL--QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
L++ T ++E K+ E QD + EL K +L++ + + L
Sbjct: 436 LRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKV 495
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
+LQ + +EV + R++ +E++ QQ L ++ + KE + + + + + +
Sbjct: 496 QLQEAERRW----EEVQSYIRKRTAEHEAA-QQDLQSKFVAKENEVQSLHSKLTDTLVSK 550
Query: 507 KLNEQKVIQY----EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ EQ+++Q ++ V ++ + + E + Q +QQ + + V
Sbjct: 551 QQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQ-IQQFHSQIAAQTSASVLA 609
Query: 563 NEELSEILAKKDQELEQ-QDKNSRGQARVIKIREEL-----INVLKNKETEQSRELAALQ 616
EEL +++A+KD++++Q +D + + R+ EEL +N L E ++ + LA Q
Sbjct: 610 -EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQ 668
Query: 617 QDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
H + +++ + + K D+I+ L L+++
Sbjct: 669 AAAAHEL---EKMQQSVYVKDDKIRLLEEQLQHE 699
Score = 59.3 bits (137), Expect = 5e-08
Identities = 118/558 (21%), Positives = 243/558 (43%), Gaps = 40/558 (7%)
Query: 122 QLYRDAIASSTPENAL--ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQG 179
Q + IA+ T + L EL + IK + +L +D+ E L +
Sbjct: 593 QQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKE-EELKDIQNMN 651
Query: 180 FELCGALRELKTQAEDAVNTVTDLSK--RACHERRTLIAVGEALVREVAKLRQDVETRNV 237
F L +++L+ A + +L K ++ + + I + E ++ ++ +E +
Sbjct: 652 FLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH--EISNKMEEFKI 709
Query: 238 MIDEIRELRSESENTKAL--EEMRHELDEERTAKLAIK-EKLTTTESQLRQTRNRVAKMD 294
+ D+ + L+SE + + L E+ ++ E+ + K EKL T E L +VA +
Sbjct: 710 LNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKE 769
Query: 295 KQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL--KTGEVTTSQLIQQRDS 352
++L +SLT V+ L+ + +V + +L++ + K G++ + + +
Sbjct: 770 EELNAIRTENSSLTKEVQDLKAKQND-QVSFASLVEELKKVIHEKDGKIKSVE-----EL 823
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE--RTETEL 410
L+AE+L+ + EK K I+ L+E++ + +Q IT + EL+ + + E
Sbjct: 824 LEAELLKVANK-EKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQ 882
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT-----KETLRVTE-DEVTT 464
++ A+ E + K + K DL E E L A +Q KE ++ +E+
Sbjct: 883 MNTMKAVLEEKEKDLA-NTGKWLQDLQEENE-SLKAHVQEVAQHNLKEASSASQFEELEI 940
Query: 465 CKREKESENKI--GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
+EKE+E K + ++ ++L +K +++ +Q + + L K+ ++ + K Y+Q
Sbjct: 941 VLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENK-LFKS-QIEQLKQQNYQQ-ASS 997
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
H + E IS L E+ LK + +N E + + + E ++ K
Sbjct: 998 FPPHEELLKVISEREKEIS--GLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLK 1055
Query: 583 NSRGQARV---IKIREELINVLKN-KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
+ V + E L K KE + + LEH+++ DE++ + + +
Sbjct: 1056 KLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECE 1115
Query: 639 EIQELFATLENKQQQIHR 656
+ + + A E Q++ R
Sbjct: 1116 KYKSVLAETEGILQKLQR 1133
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 72.9 bits (171), Expect = 3e-12
Identities = 100/488 (20%), Positives = 212/488 (43%), Gaps = 35/488 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 905 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLA 964
Query: 241 EIRELRSESEN-TKALEEMRHELDE----ERTAKLAIKEKLTTTESQLRQTRNRVAKMDK 295
++ + + +EN K L E LDE K A++E L+ ++V + K
Sbjct: 965 KVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSK 1024
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL----IQQRD 351
+ E + L G++ +Q ++ + LE RKL LK + + L +Q +
Sbjct: 1025 SKVKLEQQVDDLEGSL----EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
L+ + + QQ K+ + A+ QL++ LK+ + ++E E + E + + E
Sbjct: 1081 KLKKKEFDINQQNSKIEDEQVLAL-QLQKKLKENQARIEELEEELEAERTARAKVEKLRS 1139
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREK 469
D +EE+ + LE++ + E AE Q + L + E T K
Sbjct: 1140 DLSRELEEISER---LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRK 1196
Query: 470 ESENKIGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAH 526
+ + + +L ++ N + + K++ + E + ++ N +++I+ + +L+
Sbjct: 1197 KHADSVA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKV 1250
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
+RT+ + Q + + ++ Q+ + D + + N EL+ L +K+ + Q +RG
Sbjct: 1251 SRTLED-QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQL---TRG 1306
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFA 645
+ + E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + +
Sbjct: 1307 KLSYTQQMEDLKRQLE-EEGKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLS 1364
Query: 646 TLENKQQQ 653
++ Q
Sbjct: 1365 KANSEVAQ 1372
Score = 68.1 bits (159), Expect = 1e-10
Identities = 83/438 (18%), Positives = 195/438 (44%), Gaps = 42/438 (9%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E IKE L +E++ ++ ++ + ++ +
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGR-------IKETLEKSEARRKELEEKMVSLLQEKNDL 889
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 890 QLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 949
Query: 358 LECKQQIEKLTV------QHKSAIQQLEEDLKQTKRALQE-QCEITKREIELKERTETEL 410
E K+ I+ L + + K A + ++L + L E ++TK + L+E + L
Sbjct: 950 SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1009
Query: 411 QD---SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE----TLRVTEDEVT 463
D + + L ++LE+ + + E+E + +L+ K L++T++ +
Sbjct: 1010 DDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1069
Query: 464 TCKREK-ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
+ +K + E K+ +K ++ + I Q+ +L K +K N+ ++ + E+ +
Sbjct: 1070 DLENDKLQLEEKL---KKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEE---E 1123
Query: 523 LQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDK 582
L+A A ++ + DL +E+ ++ +L + E+ K++ E + K
Sbjct: 1124 LEAERTARAKVEKLRS-----DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ---K 1175
Query: 583 NSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQE 642
R E L+ K + +A L + +++ R+ ++ K+ + E+ +
Sbjct: 1176 MRRDLEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDD 1232
Query: 643 LFATLENKQQQIHRLEKI 660
+ + +E + LEK+
Sbjct: 1233 VTSNMEQIIKAKANLEKV 1250
Score = 62.9 bits (146), Expect = 4e-09
Identities = 98/451 (21%), Positives = 197/451 (43%), Gaps = 46/451 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESEN-TKALEEMRHELDEERTAKLAIKEK 275
V + L +E ++ + +++ +++I + ++ E ++ LE+ +E +
Sbjct: 1215 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLND 1274
Query: 276 LTTTESQLRQTRNRVAKMDKQLREAEASITSLT----GTVKMLEDQSRQKEVQLEARARK 331
TT ++L QT N ++ +QL E EA I+ LT + +ED RQ E + +A+
Sbjct: 1275 FTTQRAKL-QTEN--GELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK-NA 1330
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE 391
L +L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 1331 LAHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQR 1384
Query: 392 QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
E+ + + +L +R LQD+ A+E + AK LEK+K L E E DL +++ +
Sbjct: 1385 TEELEEAKKKLAQR----LQDAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERS 1437
Query: 452 KETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI-KLNE 510
+ +++ + +KI + K E E + Q + R L + KL
Sbjct: 1438 NAAAAALD-------KKQRNFDKILAEWKQKYEESQSE--LESSQKEARSLSTELFKLKN 1488
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNEELSE 568
YE+ + L+ R N QE + ++ Q + + + +L+ + EL
Sbjct: 1489 ----AYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQS 1544
Query: 569 ILAKKDQELEQQD-KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
L + + LE ++ K R Q +I+ E+ L K+ E ++Q + R+VD
Sbjct: 1545 ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE-------MEQAKRNHQRVVD 1597
Query: 628 EVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ + A+ E+ + + ++ +E
Sbjct: 1598 SLQTSLDAETRSRNEVLRVKKKMEGDLNEME 1628
Score = 58.8 bits (136), Expect = 6e-08
Identities = 96/470 (20%), Positives = 198/470 (42%), Gaps = 46/470 (9%)
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSE-----SENTKALEEMRHELDEERTAKLAIKEK 275
L ++ K D+ +N I++ + L + EN +EE+ EL+ ERTA+ +++
Sbjct: 1078 LEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKL 1137
Query: 276 LTTTESQLRQTRNRVAKM----DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
+ +L + R+ + Q+ + + LE+ + Q E A +K
Sbjct: 1138 RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1197
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQE 391
+S+ L + + L+ E E K +++ +T + I+ + +L++ R L++
Sbjct: 1198 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKA-KANLEKVSRTLED 1256
Query: 392 QCEITKREIELKERT-----------ETELQDSRNAIEELQAKIIELEKSKPN-----PD 435
Q + ++E +R+ +TE + +EE +A I +L + K + D
Sbjct: 1257 QANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMED 1316
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
L + E + A+ A L+ + + + E E + + + N E +
Sbjct: 1317 LKRQLEEEGKAK-NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1375
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ +T + + +L E K + Q ++D + + N + S + LQ EI DL
Sbjct: 1376 KYETDAIQRTEELEEAKK-KLAQRLQDAEEAVEAV-NAKCSSLEKTKHRLQNEIEDL--- 1430
Query: 556 LLDVVHRNEELSEILAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSR 610
++DV R+ + L KK + ++ + K Q+ + ++E ++ TE +
Sbjct: 1431 MVDV-ERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFK 1485
Query: 611 ELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
A ++ LEH + NK + +EI +L L + +H LEK+
Sbjct: 1486 LKNAYEESLEH-LETFKRENKNLQ---EEISDLTEQLGEGGKNVHELEKV 1531
Score = 56.0 bits (129), Expect = 4e-07
Identities = 116/557 (20%), Positives = 235/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL ++ + + + Y + E
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANL----EKVSRTLEDQANEYRVKLEE 1267
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
+L + TQ +L+ R E+ LI+ L R Q +E ++E
Sbjct: 1268 AQRSLNDFTTQRAKLQTENGELA-RQLEEKEALIS---QLTRGKLSYTQQMEDLKRQLEE 1323
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E ++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 1324 --EGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L++AE ++ ++ LE + + ++E L ++
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1437
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1438 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1497
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + E + ELEK + ++ +++L + L+ + +L
Sbjct: 1498 ETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEV---EKLELQSALEEAEASLE 1554
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAE-------LLNKEEIIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + N + ++ +Q + +N
Sbjct: 1555 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEV 1613
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1614 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1668
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 1669 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1728
Query: 612 LAALQQDLEHRMRIVDE 628
++ DL V+E
Sbjct: 1729 KKKMESDLTQLQSEVEE 1745
Score = 53.2 bits (122), Expect = 3e-06
Identities = 84/501 (16%), Positives = 206/501 (41%), Gaps = 30/501 (5%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1444 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1502
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + E+ ++R + E K ALEE L+ E L
Sbjct: 1503 ENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILR 1562
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1563 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVK-K 1618
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1619 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1677
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++++
Sbjct: 1678 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMES 1734
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
L+ E+ V C+ +E K + AE L KE+ T ++ +K N
Sbjct: 1735 DLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ-------DTSAHLERMKKN 1787
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
EQ ++DLQ Q L+ + +L+ +L RN E +
Sbjct: 1788 ------MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKG 1841
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEV 629
+ K ++ +++ + + + ++L++ L+ K R+ ++ + +V
Sbjct: 1842 MRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKV 1901
Query: 630 NKQIAAKADEIQELFATLENK 650
++ +A+E ++ + NK
Sbjct: 1902 QHEL-DEAEERADIAESQVNK 1921
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1638 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1696
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1697 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEK 1756
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1757 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1813
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1814 LQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKL 1873
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1874 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1925
>AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.
Length = 1302
Score = 72.9 bits (171), Expect = 3e-12
Identities = 105/502 (20%), Positives = 224/502 (44%), Gaps = 51/502 (10%)
Query: 204 SKRACH---ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMR 259
+ +AC+ E + L+ L EVA+L++ ++ + + ++ E E +A LEE+R
Sbjct: 599 NNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLE---VKNQQNIKEERERMRANLEELR 655
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRV--AKMDKQLREAEASITSLTGTVKMLEDQ 317
+ +E+ ++++L +E +LR+ + KM+++ + E ++ L+DQ
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTE---------IRDLQDQ 706
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+ +L++ R E + G + +L+Q + LQ ++L K+ E L +++
Sbjct: 707 LSEMHDELDSAKRS--EDREKGAL-IEELLQAKQDLQ-DLLIAKEGREDL-------LRK 755
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
E +L K AL+E+ +E++ LKE+ + ELQ R ++EE K +E+ S+ N
Sbjct: 756 RERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE-ATKNVEVLASRSNTSE 814
Query: 437 PTEREIDLWAE-LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
+ ++ + LQ E L+ +E+ +R + + +I + L + +E + K
Sbjct: 815 QDQAGTEMRVKLLQEENEKLQGRSEELE--RRVAQLQRQI---EDLKGDEAKAKETLKKY 869
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ + R+L E+ ++ + ++ + R + N E G + QE L K
Sbjct: 870 EGEIRQL-------EEALVHARKEEKEAVSARRALENELEGAQG-NLSQTTQEQKQLSEK 921
Query: 556 LLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAAL 615
L + + E+L + K + E E+ + K+++E+ ++++ T L
Sbjct: 922 LKEESEQKEQLRRL--KNEMENERWHLGK----TIEKLQKEMADIVEASRTSTLELQNQL 975
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXX 675
+ E R + E+ +Q+ K E ++ T Q + +E+ +
Sbjct: 976 DEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDEALTKR 1035
Query: 676 XXXXXKIAALEHELAAGLNRKE 697
+ LE+EL A + K+
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKD 1057
Score = 69.3 bits (162), Expect = 4e-11
Identities = 117/536 (21%), Positives = 230/536 (42%), Gaps = 43/536 (8%)
Query: 140 LDETMPIENIIKYPKTNLTVNQDQTDG--DILEHLSRYND-QGFELCGALRELKTQAEDA 196
L+E ++ + +T + QDQ D L+ R D + L L + K +D
Sbjct: 683 LEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDL 742
Query: 197 VNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID-EIRELR-SESENTKA 254
+ R L A+ AL EV+ Q+++ D E++ LR S E TK
Sbjct: 743 LIAKEGREDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKN 802
Query: 255 LEEM--RHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
+E + R E+ A ++ KL E++ Q R+ ++++++ + + I L G
Sbjct: 803 VEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSE--ELERRVAQLQRQIEDLKG--- 857
Query: 313 MLEDQSRQKEV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
D+++ KE + E R+L E+L + + R +L+ E+ + + + T +
Sbjct: 858 ---DEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEGAQGNLSQTTQE 914
Query: 371 HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKS 430
K QL E LK+ EQ E +R LK E E IE+LQ ++ ++ ++
Sbjct: 915 QK----QLSEKLKEES----EQKEQLRR---LKNEMENERWHLGKTIEKLQKEMADIVEA 963
Query: 431 KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE 490
L + ++D + E + + + T + EK + +Q + L +EE
Sbjct: 964 SRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMR---LMEEE 1020
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
+ + Q L K L EQ ++DL+ ++ ++ + + Q ++ ++
Sbjct: 1021 LRDYQRAQDEALTKRQLL--------EQTLKDLEYELEAKSHLKDDRSRLVKQ-MEAKVS 1071
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL--INVLKNKETEQ 608
L+M+L + + ++ LSE +++ +++EQ +N Q R + E I++ + + +
Sbjct: 1072 QLEMELEEERNNSDLLSERISRSREQMEQL-RNGLLQERAARQDLECGKISLERQNKDLK 1130
Query: 609 SRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
SR + + +V ++ +IA D ++ N Q RLE+ V L
Sbjct: 1131 SRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKEL 1186
Score = 62.9 bits (146), Expect = 4e-09
Identities = 108/496 (21%), Positives = 213/496 (42%), Gaps = 64/496 (12%)
Query: 158 TVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA- 216
T QDQ ++ L + ++ +L G EL+ + + DL + TL
Sbjct: 812 TSEQDQAGTEMRVKLLQEENE--KLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKY 869
Query: 217 ------VGEALVREVAKLRQDVETRNVMIDEIRELRSE-SENTKALEEMRHELDEERTAK 269
+ EALV + ++ V R + +E+ + S+ T+ +++ +L EE K
Sbjct: 870 EGEIRQLEEALVHARKEEKEAVSARRALENELEGAQGNLSQTTQEQKQLSEKLKEESEQK 929
Query: 270 LAIKEKLTTTESQLRQTRNRVAKMDKQLRE-AEASITSLTGTVKMLEDQSRQKEVQLEAR 328
++ E++ + K+ K++ + EAS TS L++ + +L
Sbjct: 930 EQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEM 989
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
R+L+E KT E S+L K Q ++ + Q +D TKR
Sbjct: 990 QRQLKE--KTLEAEKSRLTAM-----------KMQDGMRLMEEELRDYQRAQDEALTKRQ 1036
Query: 389 LQEQCEITKREIELKERTETELQDSRNA-IEELQAKI----IELEKSKPNPDLPTEREID 443
L EQ T +++E + ++ L+D R+ +++++AK+ +ELE+ + N DL +ER
Sbjct: 1037 LLEQ---TLKDLEYELEAKSHLKDDRSRLVKQMEAKVSQLEMELEEERNNSDLLSERISR 1093
Query: 444 LWAELQATKETL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
+++ + L R ++ K E +NK L + +++ E G +
Sbjct: 1094 SREQMEQLRNGLLQERAARQDLECGKISLERQNK-----DLKSRIIHLE---GSYRSSKE 1145
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
L+ + E ++ + E L++ R AN Q +S + L++++ +L M++ D
Sbjct: 1146 GLVVQM---EARIAELEDR---LESEERDRANLQ-----LSNRRLERKVKELVMQVDD-- 1192
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
E L+ DQ+ +Q + R ++ EE I+ L++ + + REL E
Sbjct: 1193 -------EHLSLTDQK-DQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNE 1244
Query: 621 HRMRIVDEVNKQIAAK 636
H ++ + K + K
Sbjct: 1245 HLQGQLNSMKKDLRLK 1260
Score = 60.9 bits (141), Expect = 1e-08
Identities = 57/232 (24%), Positives = 105/232 (45%), Gaps = 13/232 (5%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
+ L + + L ++E ++ + D+ L + E + EM EL+EER + E+++
Sbjct: 1036 QLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEAKVSQLEM--ELEEERNNSDLLSERISR 1093
Query: 279 TESQLRQTRN-----RVAKMDKQLREA--EASITSLTGTVKMLEDQSRQKE----VQLEA 327
+ Q+ Q RN R A+ D + + E L + LE R + VQ+EA
Sbjct: 1094 SREQMEQLRNGLLQERAARQDLECGKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEA 1153
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
R +L + L++ E + L L+ +V E Q++ + QL LK KR
Sbjct: 1154 RIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKR 1213
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
++E E R K++ + EL++ + E LQ ++ ++K LP++
Sbjct: 1214 QVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSK 1265
Score = 49.6 bits (113), Expect = 4e-05
Identities = 69/352 (19%), Positives = 158/352 (44%), Gaps = 28/352 (7%)
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
++LK+ ++Q Q + +EV + +Q KLT++ +QL+ ++K + +E+
Sbjct: 586 QTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERE 645
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNP-DLPTEREIDLWAELQATK 452
+ EL+ + +++++ + L+ EL K+ + ERE E++ +
Sbjct: 646 RMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMERE-QHQTEIRDLQ 704
Query: 453 ETLRVTEDEVTTCKREKESENKIGIQQKLAAE------LLNKEEIIGKMQIQTRELI--- 503
+ L DE+ + KR ++ E I++ L A+ L+ KE ++ + REL
Sbjct: 705 DQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTALK 764
Query: 504 ----KNIKLNEQKVIQY-EQYVRDLQAHNRTI----ANCQESPNGISYQDLQQEIMDLKM 554
+ + ++Q++ + EQY +LQA ++ N + + + + Q ++++
Sbjct: 765 GALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRV 824
Query: 555 KLLD-----VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN---KET 606
KLL + R+EEL +A+ +++E + +K E I L+
Sbjct: 825 KLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHAR 884
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
++ +E + ++ LE+ + Q + ++ E +++Q+ RL+
Sbjct: 885 KEEKEAVSARRALENELEGAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLK 936
>AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1
protein.
Length = 1357
Score = 72.9 bits (171), Expect = 3e-12
Identities = 107/497 (21%), Positives = 214/497 (43%), Gaps = 27/497 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAK---LRQDVETRNV 237
E G L++ + Q ++A T L + R V + + A+ +QD++++ V
Sbjct: 464 EKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV 523
Query: 238 MID-EIRELRSESENT----KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
+ E++ L S+ +T + LE+ +L E ++ +E L + + +
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTGEVTTSQLIQQ 349
+Q A+ TS + + L +K+ Q++ L R+ L + E +
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM 643
Query: 350 RDSLQAEVLECKQQI-EKLTVQHKSAIQQLEEDLKQTK-RALQEQCEITKREIELKERTE 407
L+AEV + + E+ H+ Q +K K R L+EQ + EI K
Sbjct: 644 NFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQ---HEISNKMEEF 700
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
L D A++ K+ L +PN D+ + E + + + K + E +
Sbjct: 701 KILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVAT 760
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK-LNEQKVIQYEQYVRDLQAH 526
++E N I + + + + Q+ L++ +K + +K + + L+A
Sbjct: 761 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 820
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEELSEILAKKDQELEQQDKNSR 585
+AN +++ QDL+QEI LK ++ +V + + ++LS + K QEL+ K
Sbjct: 821 LLKVANKEKT-----VQDLKQEIKALKEEIGNVQLEKAQQLS--ITSKVQELQNLLKGKE 873
Query: 586 GQARVIK-IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
Q +K + EE L N + ++L + L+ ++ V + N + A+ A + +EL
Sbjct: 874 EQMNTMKAVLEEKEKDLANTG-KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELE 932
Query: 645 ATLENKQQQIHRLEKIV 661
L+ K+ ++ RLE ++
Sbjct: 933 IVLKEKENELKRLEAML 949
Score = 60.5 bits (140), Expect = 2e-08
Identities = 84/454 (18%), Positives = 200/454 (44%), Gaps = 36/454 (7%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKA----------LEEMRHELDEERTAKLAI 272
REV L + + + ++L++E++ A L+ M DE +
Sbjct: 249 REVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLL 308
Query: 273 KEKLTTTESQLRQT-RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
KEK + L+++ + + + QL+E + + ++ +D+ +Q ++ +
Sbjct: 309 KEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKER 368
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED---LKQTKRA 388
+ + L ++ + Q ++ Q+ +++ ++ + +Q+E + LKQ
Sbjct: 369 SNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGI 428
Query: 389 LQEQCEITKREIELKERTETEL--QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
L++ T ++E K+ E QD + EL K +L++ + + L
Sbjct: 429 LRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKV 488
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
+LQ + +EV + R++ +E++ QQ L ++ + KE + + + + + +
Sbjct: 489 QLQEAERRW----EEVQSYIRKRTAEHEAA-QQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 507 KLNEQKVIQY----EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ EQ+++Q ++ V ++ + + E + Q +QQ + + V
Sbjct: 544 QQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQ-IQQFHSQIAAQTSASVLA 602
Query: 563 NEELSEILAKKDQELEQ-QDKNSRGQARVIKIREEL-----INVLKNKETEQSRELAALQ 616
EEL +++A+KD++++Q +D + + R+ EEL +N L E ++ + LA Q
Sbjct: 603 -EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQ 661
Query: 617 QDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
H + +++ + + K D+I+ L L+++
Sbjct: 662 AAAAHEL---EKMQQSVYVKDDKIRLLEEQLQHE 692
Score = 60.1 bits (139), Expect = 3e-08
Identities = 83/407 (20%), Positives = 188/407 (46%), Gaps = 35/407 (8%)
Query: 242 IRELRSESENTKA--LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+++L+ E+E+ KA E +H L E +A + E L++ N + +++ L+E
Sbjct: 897 LQDLQEENESLKAHVQEVAQHNLKEASSAS-----QFEELEIVLKEKENELKRLEAMLKE 951
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
E+ ++S T ++ ++D+++ + Q+E + ++ + +L++ + E+
Sbjct: 952 RESDLSSKTQLLQDVQDENKLFKSQIE-QLKQQNYQQASSFPPHEELLKVISEREKEISG 1010
Query: 360 CKQQIEKL--TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK-ERTETELQDSRNA 416
+++ L V+H+ ++ DL++ E T++ ++ K +T E Q A
Sbjct: 1011 LWNELDSLKDAVEHQ---RKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEA 1067
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLWAE--LQATKETLRVT--EDEVTTCKRE-KES 471
+ EL+AK + L+K P +P+ W + KE + T +EV + + KE+
Sbjct: 1068 V-ELEAKEV-LKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEA 1125
Query: 472 ENKIGIQQ----KLAAELLNKEEIIGKMQ--IQTRELIKNIKLNE-QKVIQYEQYVRDLQ 524
+ + Q K + L E I+ K+Q ++ E +K++E K I +Q
Sbjct: 1126 DEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--KQMQSSFT 1183
Query: 525 AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNS 584
+ + + + I ++E ++++++ + + R+ ++E+ KD E Q K
Sbjct: 1184 SSEQELERLRSENKDIENLRREREHLEMELEKAE-MERSTYVTEVRELKDLLTELQKKLD 1242
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
+ ++ EEL N+LK + + L L+ + R ++ +++K
Sbjct: 1243 DSYSEAVRQNEEL-NLLK---AQLNETLTKLRTEQNERQKVAGDLHK 1285
>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1044
Score = 72.9 bits (171), Expect = 3e-12
Identities = 81/401 (20%), Positives = 189/401 (47%), Gaps = 31/401 (7%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV-REVAKLRQDVETRNVMIDEIRE 244
L + KT+ E N V +L K H T + EAL REV + E +N +
Sbjct: 654 LDQTKTELEKKTNAVKELEKLQ-HSTETELT--EALQKREVL----ETELQNAHGELKST 706
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
LR E L++ + L+E+ T + +L + ++ + + +MD+ L+E +
Sbjct: 707 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL 766
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
V L+ R+ ++E + KL +L+ E+ + +Q +SL ++ K+Q+
Sbjct: 767 KQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQL 826
Query: 365 ---EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
E + +Q++ I QL++++++T++ ++E + K E ++ T+ +++ + +EL+
Sbjct: 827 REKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMK---EQEQYIATQYKEAIDLGQELR 883
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE--DEVTTCKREKESENKIGIQQ 479
+++ S + +L R ++QA +E R++ +++ +EK++ + +
Sbjct: 884 LTREQVQNS--HTELAEARH----QQVQAQREIERLSSELEDMKQLSKEKDAHGN-HLAE 936
Query: 480 KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNG 539
+L A + + + +MQ + ++L ++ + E Y ++ +H A + S +
Sbjct: 937 ELGASKVREAHLEARMQAEIKKLSAEVESLK------EAYHMEMISHQENHAKWKISADS 990
Query: 540 --ISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELE 578
S Q L +++ K++L + L + + +++ +E
Sbjct: 991 QKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIE 1031
Score = 66.1 bits (154), Expect = 4e-10
Identities = 83/449 (18%), Positives = 200/449 (44%), Gaps = 27/449 (6%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
++V +L + +D+ +E S+ E K + ++ + + + + L T+++
Sbjct: 603 QKVIELTGTARQVKIEMDQYKEELSKME--KEIMHLKRDGENKAMHLSQLDMILDQTKTE 660
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTG 339
L + N V +++K E +T ++LE + + +L++ R+L R+ L+
Sbjct: 661 LEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKA 720
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC-EITKR 398
+++ + L AE+ ECK +IE K + ++++ LK+ L+++ ++T
Sbjct: 721 QLSLEEKYTTIKDLTAELRECKMEIE----DKKQELLEMDQALKERNWELKQRAAQVTHL 776
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
++ ++E E++ +E K ELE + N + + + A+ Q ++ +
Sbjct: 777 DMTIREH-RGEMEQKIIKLEGTLEKS-ELELKECNKQIESLNDKLQNAKEQLREKEFIML 834
Query: 459 EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ 518
++E + +KE E +++ + + +E+ I + +L + ++L ++V
Sbjct: 835 QNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQV--QNS 892
Query: 519 YVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEELSEILAKKDQEL 577
+ +A ++ + +E + L E+ D+K + H N E+ A K +E
Sbjct: 893 HTELAEARHQQVQAQRE------IERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREA 946
Query: 578 EQQDKNSRGQARVIKIREELINVLKNKETEQ---SRELAALQQDLEHRMRIVDEVNKQIA 634
+ +R QA + K+ E+ ++ + E A + + + V ++N+Q+
Sbjct: 947 HLE---ARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLE 1003
Query: 635 AKADEIQELFATLENKQQQIHRLEKIVLA 663
E++E T+ N QQ+ +++ A
Sbjct: 1004 KAKLELEEAQDTVSNLHQQVQDRNEVIEA 1032
Score = 64.1 bits (149), Expect = 2e-09
Identities = 87/418 (20%), Positives = 181/418 (43%), Gaps = 43/418 (10%)
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLR----EAEASITSLT 308
+ L E + E+ +E K E L ++Q+ + +V ++D L E + L
Sbjct: 437 RLLTESKGEMKKENMKK---DEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLE 493
Query: 309 GTVKMLEDQSRQK-------EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL--- 358
G + E Q ++K + +L+ + L+E+ + + L QQ+ LQ E +
Sbjct: 494 GNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNG 553
Query: 359 ---ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
+ + ++EK + + +Q+ E + R ++E+CE E +LK + EL +
Sbjct: 554 ELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTAR 613
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
++ IE+++ K E+EI + + + + +++ ++ + + E E K
Sbjct: 614 QVK------IEMDQYKEELS-KMEKEI-MHLKRDGENKAMHLSQLDMILDQTKTELEKKT 665
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
++L +L + E +Q RE+++ N + + +R LQ + Q
Sbjct: 666 NAVKEL-EKLQHSTETELTEALQKREVLETELQNAHG--ELKSTLRQLQELRDVLQKAQL 722
Query: 536 S--PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
S + +DL E+ + KM++ D E+ + L +++ EL+Q+ A+V
Sbjct: 723 SLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQR------AAQV--- 773
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
L ++ E +++ L+ LE + E NKQI + D++Q L K+
Sbjct: 774 -THLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKE 830
Score = 61.3 bits (142), Expect = 1e-08
Identities = 86/501 (17%), Positives = 209/501 (41%), Gaps = 29/501 (5%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSES------ENTK---ALEEMRHELDEERTAKLAIK 273
+ ++ L+QD+ + ++ + L +ES EN K AL+ +++++ EE +
Sbjct: 416 KTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLD 475
Query: 274 EKLTTTESQL----RQTRNRVAKMDKQLREAEASITSLTGTVKMLE---DQSRQKEVQLE 326
L + +L Q K +KQL++ + L +K+ ++ ++ V L+
Sbjct: 476 SALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQ 535
Query: 327 ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK 386
++ ++ L+ + +L + L+ +V + +Q+++K Q +S+ ++L + ++ +
Sbjct: 536 HTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQK---QRESSAEKLRKMEEKCE 592
Query: 387 RALQEQCEITKREIELK---ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
A E ++ IEL + + E+ + + +++ +I+ L++ N + ++D
Sbjct: 593 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLS-QLD 651
Query: 444 LWAELQAT---KETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
+ + T K+T V E E E E + ++ L EL N + Q +
Sbjct: 652 MILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQ 711
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA-NCQESPNGISYQD--LQQEIMDLKMKLL 557
EL ++ + + + ++DL A R ++ + D L++ +LK +
Sbjct: 712 ELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAA 771
Query: 558 DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ 617
V H + + E + +Q++ + + +K + I L +K +L +
Sbjct: 772 QVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEF 831
Query: 618 DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXX 677
+ + + ++ K+I ++E+ + ++ ++Q I K + L
Sbjct: 832 IMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQN 891
Query: 678 XXXKIAALEHELAAGLNRKER 698
++A H+ ER
Sbjct: 892 SHTELAEARHQQVQAQREIER 912
Score = 44.0 bits (99), Expect = 0.002
Identities = 60/323 (18%), Positives = 135/323 (41%), Gaps = 17/323 (5%)
Query: 349 QRDSLQAEVLECKQQIEKLTVQ---HKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+ + L+ + C+++ ++L + +KS ++ L+E L+Q K E +
Sbjct: 14 EEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSE 73
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC 465
+L +SR +I +L++++ ++ + +L + A E L + + E+ +
Sbjct: 74 VMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESS 133
Query: 466 KREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN---EQKVIQYEQYVR- 521
+ E S KI Q L EL + + K Q+ + ++ + K++ E ++
Sbjct: 134 RVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKL 193
Query: 522 -----DLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQE 576
++Q + + Q S + I+ D Q+ ++ V +++E + ++Q
Sbjct: 194 AIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQH 253
Query: 577 LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAK 636
+ Q V I E L+ K + E + L+ ++ HR + +++ K
Sbjct: 254 TMNKQYEKERQRLVTGIEE-----LRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEK 308
Query: 637 ADEIQELFATLENKQQQIHRLEK 659
A +L + + K Q+ LEK
Sbjct: 309 ASNSSKLESEMTKKCSQLLTLEK 331
Score = 44.0 bits (99), Expect = 0.002
Identities = 85/441 (19%), Positives = 180/441 (40%), Gaps = 32/441 (7%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
V+ + Q E+R ++ EL ++ E + + +E E + A E+L +
Sbjct: 69 VKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQ 128
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT--G 339
++ +R + ++K + + L G L E R E+ K
Sbjct: 129 EIESSRVELRSLEKIISQLPLK-RELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVIS 187
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTV-----QHKSAIQQLE-EDLKQTKRALQEQC 393
E+ I++ + + Q+ + + Q S + LE E +K + E
Sbjct: 188 ELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESV 247
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE 453
+ + + + ++ E E Q IEEL+ K+I++E N DL ++ Q +E
Sbjct: 248 K-DQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAE--NSDLKVNMA-HRTSQFQLIQE 303
Query: 454 TLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV 513
L E + K E E K Q L E +E+I+ I KN +L EQ++
Sbjct: 304 EL--LEKASNSSKLESEMTKKCS--QLLTLEKQLEEKIVAYSSIAA----KNAEL-EQEL 354
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK 573
++ + +R L+ T N + ++++ ++ ++ ++ + R L L KK
Sbjct: 355 MEKNEKIRSLE----TNINTEHEKICLAFEKAKKIHLEQHKEMEKQIER---LEAQLEKK 407
Query: 574 DQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI 633
DQ+ ++Q+K + I ++ + L TE E+ + ++ + Q+
Sbjct: 408 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALK---ALQNQV 464
Query: 634 AAKADEIQELFATLENKQQQI 654
+ + ++++L + LE ++++
Sbjct: 465 SEETIKVRQLDSALEICKEEL 485
Score = 32.3 bits (70), Expect = 6.0
Identities = 22/107 (20%), Positives = 56/107 (52%), Gaps = 13/107 (12%)
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
EIL +K ++L++++ N + + R++ ++ + + TE + + L+ +LE++ I+
Sbjct: 44 EILKEKLRQLKEENNNGKEKLRIMAVKNSEVMA---QLTESRQSILKLESELENKDEILR 100
Query: 628 ----------EVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
E+ ++AA+ + + +E+ + ++ LEKI+ L
Sbjct: 101 DKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQL 147
>AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein.
Length = 1498
Score = 72.9 bits (171), Expect = 3e-12
Identities = 94/455 (20%), Positives = 204/455 (44%), Gaps = 24/455 (5%)
Query: 210 ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESE-NTKALEEMRHELDEERTA 268
E+RT A L REVA++RQ + + ++ R E E + ++L+ + ++ A
Sbjct: 893 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEVETHLQSLQFDKEQMVAVTEA 952
Query: 269 KLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
A+K+++ E ++ R + + +++R + +TS K ++ + + E +
Sbjct: 953 NEALKKQI---EELQQEARKAITEQKQKMRRLGSDLTSAQ---KEMKTKHKAYENAVGIL 1006
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
+R+L+E+L E ++L Q R Q + + + ++ +Q + ++
Sbjct: 1007 SRRLQEALAAREAADAELGQLR--AQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE 1064
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
LQE +T +E+E EL+D + KI LE+S L E E L
Sbjct: 1065 LQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGL 1124
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
+ LR + T ++E++ + + ++ A L KEE +M+ + L +++
Sbjct: 1125 GQSNAALREHNSILETALAKREAD-LVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEK 1183
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-S 567
++KV ++ V A + N ++ E+ ++K +L H ++L +
Sbjct: 1184 EKEKVNSLKEQV--------AAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQA 1235
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
E + +E + + ++ QA + + R +L +L+ + EQ + A Q++E+ VD
Sbjct: 1236 EADDLQIREGKHSQEIAQFQAELAEARAQL-QLLQKQLDEQLSKQPAGNQEMENLKWEVD 1294
Query: 628 EVNKQIAAKADEI----QELFATLENKQQQIHRLE 658
+ ++I + ++ Q+ + LE QQ + ++
Sbjct: 1295 QKEREIQSLKQQLDLTEQQGWKELEGLQQLLQNVK 1329
Score = 66.5 bits (155), Expect = 3e-10
Identities = 105/515 (20%), Positives = 234/515 (45%), Gaps = 56/515 (10%)
Query: 161 QDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA 220
Q + I E + G +L A +E+KT+ + N V LS+R + +A EA
Sbjct: 964 QQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRL----QEALAAREA 1019
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTE 280
E+ +LR + + + +++ +A+ + L++E ++E + T
Sbjct: 1020 ADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE------LQEVIALTS 1073
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+L ++R +V +++ +L+E+ +K LE+ +++ ++LE KL TG
Sbjct: 1074 QELEESREKVLELEDELQESR----GFRKKIKRLEESNKKLALELEHEKGKL-----TGL 1124
Query: 341 VTTSQLIQQRDS-LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEIT 396
++ +++ +S L+ + + + + +L +Q ++ +Q+ EE+ +Q K +ALQ E
Sbjct: 1125 GQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKE 1184
Query: 397 KREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
K ++ LKE+ ++ + +A +EL + K + + L +LQA + L
Sbjct: 1185 KEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKE----LQAKEHLVQKLQAEADDL 1240
Query: 456 RVTE----DEVTTCKRE-KESENKIGIQQKLAAELLNKEEI-----------IGKMQIQT 499
++ E E+ + E E+ ++ + QK E L+K+ + + + +
Sbjct: 1241 QIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPAGNQEMENLKWEVDQKEREI 1300
Query: 500 RELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQD---LQQEIMDLKMKL 556
+ L + + L EQ+ + + ++ L + ++ + ++ +D LQ ++ +LK +
Sbjct: 1301 QSLKQQLDLTEQQGWKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNM 1360
Query: 557 LDVVHRNEELSEIL---AKKDQELEQQDKNSRGQARVIKIRE-----ELINVLKNKETEQ 608
++ +N++L L A K ++ + + +S A IKI + L+ L
Sbjct: 1361 KTLLQQNQQLKLDLRRGAAKTRKEPKGEASSSNPATPIKIPDCPVPASLLEELLRPPPAV 1420
Query: 609 SRE-LAALQQDLEHRMRIVDEVNKQIAAKADEIQE 642
S+E L L L+ + +D + +Q+ A + E
Sbjct: 1421 SKEPLKNLNSCLQQLKQEMDSLRRQMEEHALTVHE 1455
Score = 65.7 bits (153), Expect = 5e-10
Identities = 117/564 (20%), Positives = 249/564 (44%), Gaps = 49/564 (8%)
Query: 126 DAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGA 185
++ A+ T E L++L E M +E ++ +L +Q + L+ +
Sbjct: 397 ESSAAETQEEMLQVLKEKMRLEGQLE--ALSLEASQALKEKAELQAQLAALSTKLQAQVE 454
Query: 186 LRELKTQAEDAVNTVTDLSKRACHE-RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
Q +D++++ D K++C + R + + L + A L V ++ +
Sbjct: 455 CSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQR 514
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
L ++ E+ + R L ++ T +++++T +SQL+Q + + +L+ ++A I
Sbjct: 515 LMAKVEDMQ-----RSMLSKDNTVH-DLRQQMTALQSQLQQVQLERTTLTSKLKASQAEI 568
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRE--SLKTGEVTTSQLIQ----QRDSLQAEVL 358
+SL + + +Q + EAR R E ++ G++T + L++ + SL ++
Sbjct: 569 SSLQSVRQWYQ---QQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLT 625
Query: 359 ECKQQIEKLTVQHKSAIQQLEED----------LKQTKRALQEQCEITKREIELKERTET 408
E + + K + + +Q +E D +++ K ++E + E E +
Sbjct: 626 ETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQ 685
Query: 409 ELQDSRNAIEEL--QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
+ DS ++E+ Q K+ L++ + L E +DL +L T+E L+ E + +
Sbjct: 686 RMADSAASLEQQLEQVKLTLLQRDQQLEALQQE-HLDLMKQLTLTQEALQSREQSLDALQ 744
Query: 467 -REKESENKIGIQQKLAAE------LLNKEEIIGKMQIQT-----RELIKNIKLNEQKVI 514
R E + ++G Q AA LL E+II + +Q EL + + E+
Sbjct: 745 TRYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTE 804
Query: 515 QYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKD 574
+ + + L+ I + Q L++++ +K + L E KD
Sbjct: 805 ETSETLEKLR-EELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKD 863
Query: 575 QEL-EQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDL-EHRMRIVD-EVNK 631
Q + E + R + + ++R+EL+ V K T ++ EL+ L +++ + R + D E +
Sbjct: 864 QLISELKATRKRLDSELKELRQELMQVHGEKRTAEA-ELSRLHREVAQVRQHMADLEGHL 922
Query: 632 QIAAK-ADEIQELFATLENKQQQI 654
Q A K DE++ +L+ ++Q+
Sbjct: 923 QSAQKERDEVETHLQSLQFDKEQM 946
Score = 52.8 bits (121), Expect = 4e-06
Identities = 103/523 (19%), Positives = 225/523 (43%), Gaps = 58/523 (11%)
Query: 158 TVNQDQTDGDILEHLS-RYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
T+ Q + D+L+ + + DQG E+ G +R + D++ + L A + ++
Sbjct: 354 TLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRR----DSICSSVSLESSAAETQEEMLQ 409
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSE----SENTKALEEMRHELDEERTAKLAI 272
V + +R +L + + E EL+++ S +A E H + + + +
Sbjct: 410 VLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDS---L 466
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
++ T + + + L AS+ S +++ E+Q ++ L A+ +
Sbjct: 467 SSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQR----LMAKVEDM 522
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE-EDLKQTKRALQE 391
+ S+ + + T L QQ +LQ+++ + Q+E+ T+ K Q E L+ ++ Q+
Sbjct: 523 QRSMLSKDNTVHDLRQQMTALQSQLQQV--QLERTTLTSKLKASQAEISSLQSVRQWYQQ 580
Query: 392 QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
Q + + E + R + E+ + + QA ++E K
Sbjct: 581 QLALAQ---EARVRLQGEMAHIQVG-QMTQAGLLEHLKL--------------------- 615
Query: 452 KETLRVTEDEVTTCKREKESENKIGIQ-QKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
E + +++ T R + + +I Q Q + A++L++E MQIQ + + L +
Sbjct: 616 -ENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAF--MQIQEAKTMVEEDL-Q 671
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ--QEIMDLKMKLLDVVHRNEELSE 568
+++ ++E LQ + A+ ++ + LQ Q++ L+ + LD++ + E
Sbjct: 672 RRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQE 731
Query: 569 ILAKKDQELEQ-QDKNSRGQARVIKI------REELINVLKNKETEQSRELAALQQDLEH 621
L ++Q L+ Q + QAR+ ++ RE+ I +L+N++ L A + E
Sbjct: 732 ALQSREQSLDALQTRYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEE 791
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
R + + ++ +++L L K Q+ L++ AL
Sbjct: 792 LDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAAL 834
>Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein.
Length = 1356
Score = 72.5 bits (170), Expect = 5e-12
Identities = 105/445 (23%), Positives = 202/445 (45%), Gaps = 39/445 (8%)
Query: 233 ETRNVMIDEIRELRSESENTK-ALEEMRHELDEERTAKL-AIKEKLTTTESQLRQTRNRV 290
+ R M EI L+ E+ + A+ ++L+ +++A+L +++ ++L + ++
Sbjct: 409 QVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKL 468
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL-----RESLKTGEVTTSQ 345
+ + Q + AE + T L V++ E + R +EVQ R R ++ L++ V
Sbjct: 469 QQEEVQKKNAEQAATQLK--VQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKEN 526
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL---EEDLKQTKRALQEQCEITKREIEL 402
+Q S + L KQQ+E+ +Q + Q+ EE L+ + + EQ E K +I+
Sbjct: 527 EVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQ- 585
Query: 403 KERTETELQDSRNAI-EELQAKIIELEKS-KPNPD-LPTEREIDLWAELQATKETLRVTE 459
+ ++ Q S + + EEL I E +K K D L +ER+ L + +E L+ +
Sbjct: 586 QFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERD-----RLTSKEEELKDIQ 640
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
+ K E + + +Q AA L K MQ I+L E+++ Q+
Sbjct: 641 NMNFLLKAEVQKLQALANEQAAAAHELEK------MQQSVYVKDDKIRLLEEQL----QH 690
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
+ I N Q Q LQ + + K DVV E++ + + +KD++L+
Sbjct: 691 EISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNK--DVV---EQMEKCIQEKDEKLKT 745
Query: 580 QDKNSRGQARVIKIREELINVLKNKE---TEQSRELAALQQDLEHRMRIVDEVNKQIAAK 636
++ + +EE +N ++ + T++ ++L A Q D +V+E+ K I K
Sbjct: 746 VEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEK 805
Query: 637 ADEIQELFATLENKQQQIHRLEKIV 661
+I+ + LE + ++ EK V
Sbjct: 806 DGKIKSVEELLEAELLKVANKEKTV 830
Score = 71.3 bits (167), Expect = 1e-11
Identities = 107/497 (21%), Positives = 213/497 (42%), Gaps = 27/497 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAK---LRQDVETRNV 237
E G L++ + Q ++A T L + R V + + A+ +QD++++ V
Sbjct: 463 EKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV 522
Query: 238 MID-EIRELRSESENT----KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAK 292
+ E++ L S+ +T + LE+ +L E ++ +E L + + +
Sbjct: 523 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 582
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTGEVTTSQLIQQ 349
+Q A+ TS + + L +K+ Q++ L R+ L + E +
Sbjct: 583 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM 642
Query: 350 RDSLQAEVLECKQQI-EKLTVQHKSAIQQLEEDLKQTK-RALQEQCEITKREIELKERTE 407
L+AEV + + E+ H+ Q +K K R L+EQ + EI K
Sbjct: 643 NFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQ---HEISNKMEEF 699
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
L D A++ K+ L +PN D+ + E + + + K + E +
Sbjct: 700 KILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVAT 759
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK-LNEQKVIQYEQYVRDLQAH 526
++E N I + + + + Q+ L++ +K + +K + + L+A
Sbjct: 760 KEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE 819
Query: 527 NRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEELSEILAKKDQELEQQDKNSR 585
+AN +++ QDL+QEI LK ++ +V + + ++LS + K QEL+ K
Sbjct: 820 LLKVANKEKT-----VQDLKQEIKALKEEIGNVQLEKAQQLS--ITSKVQELQNLLKGKE 872
Query: 586 GQARVIK-IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
Q +K + EE L N + ++L + L+ ++ V + N + A+ A + +EL
Sbjct: 873 EQMNTMKAVLEEKEKDLANTG-KWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELE 931
Query: 645 ATLENKQQQIHRLEKIV 661
L+ K ++ RLE ++
Sbjct: 932 IVLKEKGNELKRLEAML 948
Score = 69.7 bits (163), Expect = 3e-11
Identities = 91/451 (20%), Positives = 207/451 (45%), Gaps = 27/451 (5%)
Query: 224 EVAKLRQD-VETRNVMIDEIRELRSESENTKALEEMRHELD------EERTAKLAIKEKL 276
E+ KLRQD N + ++ +L+ E K E+ +L E R ++ +
Sbjct: 446 ELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 505
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
T E + Q ++ +K + E ++ + LT T+ + + Q Q+ +QL +K
Sbjct: 506 RTAEHEAAQ-QDLQSKFVAKENEVQSLHSKLTDTL-VSKQQLEQRLMQLMESEQKRVNKE 563
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
++ ++ +++Q ++L+A++ + QI T A ++L + + + + +++ +
Sbjct: 564 ESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA-EELHKVIAEKDKQIKQTEDSL 622
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET-L 455
E + E EL+D +N L+A++ +L+ + N E++ + K+ +
Sbjct: 623 ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQ-ALANEQAAAAHELEKMQQSVYVKDDKI 681
Query: 456 RVTEDEVTTCKREKESENKIGIQQK--LAAELLNKEEIIGKMQIQ--TRELIKNIKLNEQ 511
R+ E+++ K E KI Q L +E+ + ++ + + ++ K I+ ++
Sbjct: 682 RLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDE 741
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLDVVHRN---EEL 566
K+ E+ L+ +A +E N I ++ L +E+ DLK K D V EEL
Sbjct: 742 KLKTVEEL---LETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEEL 798
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI- 625
+++ +KD +++ ++ + + +E+ + LK + E+ +Q + ++ I
Sbjct: 799 KKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSIT 858
Query: 626 --VDEVNKQIAAKADEIQELFATLENKQQQI 654
V E+ + K +++ + A LE K++ +
Sbjct: 859 SKVQELQNLLKGKEEQMNTMKAVLEEKEKDL 889
Score = 60.5 bits (140), Expect = 2e-08
Identities = 84/454 (18%), Positives = 200/454 (44%), Gaps = 36/454 (7%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKA----------LEEMRHELDEERTAKLAI 272
REV L + + + ++L++E++ A L+ M DE +
Sbjct: 248 REVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLL 307
Query: 273 KEKLTTTESQLRQT-RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
KEK + L+++ + + + QL+E + + ++ +D+ +Q ++ +
Sbjct: 308 KEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKER 367
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED---LKQTKRA 388
+ + L ++ + Q ++ Q+ +++ ++ + +Q+E + LKQ
Sbjct: 368 SNVVMTRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGI 427
Query: 389 LQEQCEITKREIELKERTETEL--QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
L++ T ++E K+ E QD + EL K +L++ + + L
Sbjct: 428 LRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKV 487
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
+LQ + +EV + R++ +E++ QQ L ++ + KE + + + + + +
Sbjct: 488 QLQEAERRW----EEVQSYIRKRTAEHEAA-QQDLQSKFVAKENEVQSLHSKLTDTLVSK 542
Query: 507 KLNEQKVIQY----EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ EQ+++Q ++ V ++ + + E + Q +QQ + + V
Sbjct: 543 QQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQ-IQQFHSQIAAQTSASVLA 601
Query: 563 NEELSEILAKKDQELEQ-QDKNSRGQARVIKIREEL-----INVLKNKETEQSRELAALQ 616
EEL +++A+KD++++Q +D + + R+ EEL +N L E ++ + LA Q
Sbjct: 602 -EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQ 660
Query: 617 QDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
H + +++ + + K D+I+ L L+++
Sbjct: 661 AAAAHEL---EKMQQSVYVKDDKIRLLEEQLQHE 691
Score = 59.3 bits (137), Expect = 5e-08
Identities = 83/407 (20%), Positives = 188/407 (46%), Gaps = 35/407 (8%)
Query: 242 IRELRSESENTKA--LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+++L+ E+E+ KA E +H L E +A + E L++ N + +++ L+E
Sbjct: 896 LQDLQEENESLKAHVQEVAQHNLKEASSAS-----QFEELEIVLKEKGNELKRLEAMLKE 950
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
E+ ++S T ++ ++D+++ + Q+E + ++ + +L++ + E+
Sbjct: 951 RESDLSSKTQLLQDVQDENKLFKSQIE-QLKQQNYQQASSFPPHEELLKVISEREKEISG 1009
Query: 360 CKQQIEKL--TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK-ERTETELQDSRNA 416
+++ L V+H+ ++ DL++ E T++ ++ K +T E Q A
Sbjct: 1010 LWNELDSLKDAVEHQ---RKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEA 1066
Query: 417 IEELQAKIIELEKSKPNPDLPTEREIDLWAE--LQATKETLRVT--EDEVTTCKRE-KES 471
+ EL+AK + L+K P +P+ W + KE + T +EV + + KE+
Sbjct: 1067 V-ELEAKEV-LKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEA 1124
Query: 472 ENKIGIQQ----KLAAELLNKEEIIGKMQ--IQTRELIKNIKLNE-QKVIQYEQYVRDLQ 524
+ + Q K + L E I+ K+Q ++ E +K++E K I +Q
Sbjct: 1125 DEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--KQMQSSFT 1182
Query: 525 AHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNS 584
+ + + + I ++E ++++++ + + R+ ++E+ KD E Q K
Sbjct: 1183 SSEQELERLRSENKDIENLRREREHLEMELEKAE-MERSTYVTEVRELKDLLTELQKKLD 1241
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
+ ++ EEL N+LK + + L L+ + R ++ +++K
Sbjct: 1242 DSYSEAVRQNEEL-NLLK---AQLNETLTKLRTEQNERQKVAGDLHK 1284
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain
(1151 AA) protein.
Length = 1151
Score = 72.5 bits (170), Expect = 5e-12
Identities = 101/483 (20%), Positives = 211/483 (43%), Gaps = 25/483 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 119 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 178
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 179 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 236
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + L + L+ +
Sbjct: 237 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERL 296
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ ++ L + + Q L L++ + LQ + E + E+E + +++ R+ +
Sbjct: 297 KKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 355
Query: 418 -EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESENK 474
EL+ LE++ + E AE Q + L + E T K+ +
Sbjct: 356 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 415
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ +L ++ N + + K++ + E + ++ N +++I+ + +L+ RT+
Sbjct: 416 VA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKMCRTLE 469
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ Q + + ++ Q+ + DL + + N ELS L +K+ + Q +RG+
Sbjct: 470 D-QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL---TRGKLTYT 525
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATLENK 650
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + + ++
Sbjct: 526 QQLEDLKRQLE-EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSE 583
Query: 651 QQQ 653
Q
Sbjct: 584 VAQ 586
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 47/465 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
V + L +E ++ + +++ +++I + ++ E K + +++E R+ + +
Sbjct: 429 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE--KMCRTLEDQMNEHRSKAEETQRSV 486
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTV---KMLEDQSRQKEVQLEARARKL 332
SQ + + ++ +QL E EA I+ LT G + + LED RQ E +++A+ L
Sbjct: 487 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-NAL 545
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
+L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 546 AHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQRT 599
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATK 452
E+ + + +L +R LQ++ A+E + AK LEK+K L E E DL +++ +
Sbjct: 600 EELEEAKKKLAQR----LQEAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERSN 652
Query: 453 ETLRVTE------DEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ D++ ++K ES++++ QK A L + + ++ E ++
Sbjct: 653 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 712
Query: 505 NIKLNEQKVIQYE--QYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKL---- 556
K E K +Q E L + +TI ++ + + +LQ + + + L
Sbjct: 713 TFK-RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 771
Query: 557 -------LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ E+ LA+KD+E+EQ +N RV+ + ++ E
Sbjct: 772 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN---HLRVVDSLQTSLDAETRSRNEAL 828
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R ++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 829 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 873
Score = 65.7 bits (153), Expect = 5e-10
Identities = 82/438 (18%), Positives = 199/438 (45%), Gaps = 34/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E +KE L +E++ ++ ++ + ++ +
Sbjct: 51 KIKPLLKSAEREKEMASMKEEFTR-------LKEALEKSEARRKELEEKMVSLLQEKNDL 103
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 104 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 163
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 164 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 223
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 224 DDLQAEEDKVNTLTKAK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 276
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL-IKNIKLNEQKVI--QYEQYVRDLQAHNRTIA 531
+ Q+ + +K+++ +++ + EL N ++ +++ + Q ++ +++LQA +
Sbjct: 277 L-TQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 335
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRG 586
E+ + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 336 EELEAER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRRD 393
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 394 LEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 450
Query: 647 LENKQQQIHRLEKIVLAL 664
+E + LEK+ L
Sbjct: 451 MEQIIKAKANLEKMCRTL 468
Score = 59.7 bits (138), Expect = 3e-08
Identities = 90/456 (19%), Positives = 190/456 (41%), Gaps = 38/456 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLT 277
+AL ++ K ++++ R ++E EL +E +E++R +L E ++E
Sbjct: 314 QALGSQLQKKLKELQARIEELEE--ELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 371
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
T Q+ + R A+ K R+ E + T L + +L + L+ +
Sbjct: 372 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 431
Query: 338 TGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
E S+ + D + + ++++ K +EK+ + + + ++T+R++ +
Sbjct: 432 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND--- 488
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQ 449
+T + +L +TE + ++E +A I +L + K DL + E ++ A+
Sbjct: 489 LTSQRAKL----QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-N 543
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
A L+ + + + E E + + + N E + + +T + + +L
Sbjct: 544 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 603
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
E K ++ +A A C + LQ EI DL ++DV R+ +
Sbjct: 604 EAKKKLAQRLQEAEEAVEAVNAKCSSLEK--TKHRLQNEIEDL---MVDV-ERSNAAAAA 657
Query: 570 LAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L KK + ++ + K Q+ + ++E ++ TE + A ++ LEH +
Sbjct: 658 LDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFKLKNAYEESLEH-LE 712
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
NK + +EI +L L + + IH LEK+
Sbjct: 713 TFKRENKNLQ---EEISDLTEQLGSSGKTIHELEKV 745
Score = 59.3 bits (137), Expect = 5e-08
Identities = 91/502 (18%), Positives = 222/502 (44%), Gaps = 34/502 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 658 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 716
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + I E+ ++R + E K ALEE L+ E L
Sbjct: 717 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 776
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 777 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK-K 832
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 833 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 891
Query: 391 EQCEITKREIELKERTETELQDSRN-AIEEL--QAKIIELEKSKPNPDLPTEREIDLWAE 447
+ + + E+E + + SR A EEL ++ ++L S+ + ++++D A+
Sbjct: 892 RRNNLLQAELEELRAVVEQTERSRKLADEELIETSERVQLLHSQNTSLINQKKKMD--AD 949
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE----IIGKMQIQTRELI 503
L + + E+ V C+ +E K + AE L KE+ + +M+ + I
Sbjct: 950 LSQLQTEV---EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTI 1006
Query: 504 KNI--KLNEQKVIQY---EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD 558
K++ +L+E + I ++ ++ L+A R + N E+ + + + + + + ++ +
Sbjct: 1007 KDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESV-KGMRKSERRIKE 1065
Query: 559 VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQD 618
+ ++ EE + L + +++ + R + EE N +K + EL +
Sbjct: 1066 LTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL----DE 1121
Query: 619 LEHRMRIVDEVNKQIAAKADEI 640
E R I + ++ AK+ +I
Sbjct: 1122 AEERADIAESQVNKLRAKSRDI 1143
Score = 55.2 bits (127), Expect = 7e-07
Identities = 121/557 (21%), Positives = 234/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL + + EH S+ E
Sbjct: 427 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEHRSKAE----E 481
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
++ +L +Q +LS R E+ LI+ L R Q +E ++E
Sbjct: 482 TQRSVNDLTSQRAKLQTENGELS-RQLDEKEALIS---QLTRGKLTYTQQLEDLKRQLEE 537
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E+++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 538 --EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 595
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L+EAE ++ ++ LE + + ++E L ++
Sbjct: 596 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 651
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 652 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 711
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + I ELEK + L E+ ++L + L+ + +L
Sbjct: 712 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ--LEAEK-MELQSALEEAEASLE 768
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEE-------IIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + E+ ++ +Q + +N
Sbjct: 769 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 827
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 828 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 882
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 883 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADEELIETSERVQLLHSQNTSLINQ 942
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 943 KKKMDADLSQLQTEVEE 959
Score = 45.6 bits (103), Expect = 6e-04
Identities = 60/296 (20%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 852 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 910
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + D ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 911 TERSRKLADEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 970
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 971 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1027
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1028 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1087
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1088 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1139
>BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein
protein.
Length = 724
Score = 72.5 bits (170), Expect = 5e-12
Identities = 103/465 (22%), Positives = 207/465 (44%), Gaps = 42/465 (9%)
Query: 229 RQDVETRNVMIDEIRELRS-----ESENTKALEEMRHELDEERTAKLAIKEKLTTT---E 280
+Q + R ++ I ELR+ E+EN+ M H + + + + EK + + E
Sbjct: 232 KQYEKERQGLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLE 291
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
S++ + +++ ++KQL E + +S+ LE Q E QLE + ++ +E KT
Sbjct: 292 SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELE-QELMLEAQLEKKDQQFKEQEKTMS 350
Query: 341 VTTSQLIQQR---DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCE 394
+ +I ++ +SL + E K +++K ++ A++ L+ + + R L E
Sbjct: 351 MLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALE 410
Query: 395 ITKREIEL--------KERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
I K E+ L KE+ E +L+ + LQ EL+ + +E+ + L
Sbjct: 411 IRKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQK---ELKIKNHSLQETSEQNVILQH 467
Query: 447 ELQATK-----ETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRE 501
LQ + ET+R E E T K EK+ ++Q+L + + E + KM+ +
Sbjct: 468 TLQQQQQMLQQETIRNGELEDTQTKLEKQVSK---LEQELQKQRESSAEKLRKMEEKCES 524
Query: 502 LIKNIKLNEQKVIQYEQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
L QKVI+ R ++ ++ + I + E + + LD++
Sbjct: 525 AAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMI 584
Query: 561 HRNEELSEILAKKD--QELEQQDKNSRGQ-ARVIKIREELINVLKNKETEQS---RELAA 614
++ +E+ K + +ELE+ ++ + ++ RE L L+N E R+L
Sbjct: 585 -LDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQE 643
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
L+ L+ ++E I E++E +E+K+Q++ +++
Sbjct: 644 LRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQ 688
Score = 62.9 bits (146), Expect = 4e-09
Identities = 82/428 (19%), Positives = 189/428 (44%), Gaps = 35/428 (8%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
S+ + + C L L+ Q E+ + + ++ + + L+ + L ++ + ++
Sbjct: 288 SKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMLEAQ-LEKKDQQFKEQE 346
Query: 233 ETRNVMIDEIRELRSESENT-KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
+T +++ +I + E+ + L E + E+ +E K E L ++Q+ + +V
Sbjct: 347 KTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKK---DEALKALQNQVSEETIKVR 403
Query: 292 KMDKQLR----EAEASITSLTGTVKMLEDQSRQK-------EVQLEARARKLRESLKTGE 340
++D L E + L G + E Q ++K + +L+ + L+E+ +
Sbjct: 404 QLDSALEIRKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNV 463
Query: 341 VTTSQLIQQRDSLQAEVL------ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
+ L QQ+ LQ E + + + ++EK + + +Q+ E + R ++E+CE
Sbjct: 464 ILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE 523
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET 454
E +LK + EL + ++ IE+++ K E+EI + + +
Sbjct: 524 SAAHEADLKRQKVIELTGTARQVK------IEMDQYKEELS-KMEKEI-MHLKRDGENKA 575
Query: 455 LRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI 514
+ +++ ++ + + E E K ++L +L + E +Q RE+++ N
Sbjct: 576 MHLSQLDMILDQTKTELEKKTNAVKEL-EKLQHSTETELTEALQKREVLETELQNAHG-- 632
Query: 515 QYEQYVRDLQAHNRTIANCQES--PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK 572
+ + +R LQ + Q S + +DL E+ + KM++ D E+ + L +
Sbjct: 633 ELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKE 692
Query: 573 KDQELEQQ 580
++ EL+Q+
Sbjct: 693 RNWELKQR 700
Score = 41.9 bits (94), Expect = 0.007
Identities = 45/212 (21%), Positives = 102/212 (48%), Gaps = 31/212 (14%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
EL G R++K + + ++ + K H +R GE +++L ++++D
Sbjct: 538 ELTGTARQVKIEMDQYKEELSKMEKEIMHLKRD----GENKAMHLSQL-------DMILD 586
Query: 241 EIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTT----TESQLRQTRNRVAKMDK 295
+ + EL ++ K LE+++H + E T L +E L T +L+ T ++ ++
Sbjct: 587 QTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRD 646
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
L++A+ S+ T+K L + R+ ++++E + ++L E Q +++R+
Sbjct: 647 VLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEM--------DQALKERN---- 694
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
E KQ+ ++T I++ +++Q K+
Sbjct: 695 --WELKQRAAQVT-HLDMTIREHRGEMEQKKK 723
Score = 41.5 bits (93), Expect = 0.010
Identities = 57/298 (19%), Positives = 122/298 (40%), Gaps = 14/298 (4%)
Query: 371 HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKS 430
+KS ++ L+E L+Q K E + +L +SR +I +L++++ ++
Sbjct: 14 YKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEI 73
Query: 431 KPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEE 490
+ +L + A E L + + E+ + + E S KI Q L EL +
Sbjct: 74 LRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKS 133
Query: 491 IIGKMQIQTRELIKNIKLN---EQKVIQYEQYVR------DLQAHNRTIANCQESPNGIS 541
+ K Q+ + ++ + K++ E ++ ++Q + + Q S + I+
Sbjct: 134 YLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLIT 193
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVL 601
D Q+ ++ V +++E + ++Q + Q V I E L
Sbjct: 194 CNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQGLVTGIEE-----L 248
Query: 602 KNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ K + E + L+ ++ HR + +++ KA +L + + K Q+ LEK
Sbjct: 249 RTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEK 306
Score = 40.7 bits (91), Expect = 0.017
Identities = 58/316 (18%), Positives = 140/316 (44%), Gaps = 18/316 (5%)
Query: 383 KQTKRALQEQCEITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
K+ KR LQE+C + K E+E LKE+ +++ N E+L +I+ ++ S+ L R+
Sbjct: 2 KENKR-LQERCGLYKSELEILKEKLRQLKEENNNGKEKL--RIMAVKNSEVMAQLTESRQ 58
Query: 442 --IDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQT 499
+ L +EL+ E LR D+ + +E + ++ Q + +L +E ++++++
Sbjct: 59 SILKLESELENKDEILR---DKFSLMNENRELKVRVAAQNE-RLDLCQQEIESSRVELRS 114
Query: 500 RELIKNIKLNEQKVIQYEQYVRDLQ------AHNRTIANCQESPNGISYQDLQQEIMDLK 553
E I + ++++ ++ Y+ Q +R I C+ + IS ++ I + +
Sbjct: 115 LEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAE 174
Query: 554 MKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELA 613
++ L +LS+ L + + ++ K S + +K+ + K+ Q
Sbjct: 175 IQKLHANLTANQLSQSLITCN-DSQESSKLSSLETEPVKLGGHQV-AESVKDQNQHTMNK 232
Query: 614 ALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXX 673
+++ + + ++E+ ++ E +L + ++ Q +++ +L
Sbjct: 233 QYEKERQGLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLES 292
Query: 674 XXXXXXXKIAALEHEL 689
++ LE +L
Sbjct: 293 EMTKKCSQLLTLEKQL 308
Score = 36.3 bits (80), Expect = 0.37
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 8/147 (5%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV-REVAKLRQDVETRNVMIDEIRE 244
L + KT+ E N V +L K H T + EAL REV + E +N +
Sbjct: 585 LDQTKTELEKKTNAVKELEKLQ-HSTETELT--EALQKREVL----ETELQNAHGELKST 637
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
LR E L++ + L+E+ T + +L + ++ + + +MD+ L+E +
Sbjct: 638 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL 697
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARK 331
V L+ R+ ++E + +K
Sbjct: 698 KQRAAQVTHLDMTIREHRGEMEQKKKK 724
>BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein.
Length = 873
Score = 72.5 bits (170), Expect = 5e-12
Identities = 105/445 (23%), Positives = 202/445 (45%), Gaps = 39/445 (8%)
Query: 233 ETRNVMIDEIRELRSESENTK-ALEEMRHELDEERTAKL-AIKEKLTTTESQLRQTRNRV 290
+ R M EI L+ E+ + A+ ++L+ +++A+L +++ ++L + ++
Sbjct: 410 QVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKL 469
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL-----RESLKTGEVTTSQ 345
+ + Q + AE + T L V++ E + R +EVQ R R ++ L++ V
Sbjct: 470 QQEEVQKKNAEQAATQLK--VQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKEN 527
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL---EEDLKQTKRALQEQCEITKREIEL 402
+Q S + L KQQ+E+ +Q + Q+ EE L+ + + EQ E K +I+
Sbjct: 528 EVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQ- 586
Query: 403 KERTETELQDSRNAI-EELQAKIIELEKS-KPNPD-LPTEREIDLWAELQATKETLRVTE 459
+ ++ Q S + + EEL I E +K K D L +ER+ L + +E L+ +
Sbjct: 587 QFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERD-----RLTSKEEELKDIQ 641
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
+ K E + + +Q AA L K MQ I+L E+++ Q+
Sbjct: 642 NMNFLLKAEVQKLQALANEQAAAAHELEK------MQQSVYVKDDKIRLLEEQL----QH 691
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
+ I N Q Q LQ + + K DVV E++ + + +KD++L+
Sbjct: 692 EISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNK--DVV---EQMEKCIQEKDEKLKT 746
Query: 580 QDKNSRGQARVIKIREELINVLKNKE---TEQSRELAALQQDLEHRMRIVDEVNKQIAAK 636
++ + +EE +N ++ + T++ ++L A Q D +V+E+ K I K
Sbjct: 747 VEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEK 806
Query: 637 ADEIQELFATLENKQQQIHRLEKIV 661
+I+ + LE + ++ EK V
Sbjct: 807 DGKIKSVEELLEAELLKVANKEKTV 831
Score = 62.5 bits (145), Expect = 5e-09
Identities = 85/425 (20%), Positives = 194/425 (45%), Gaps = 24/425 (5%)
Query: 224 EVAKLRQD-VETRNVMIDEIRELRSESENTKALEEMRHELD------EERTAKLAIKEKL 276
E+ KLRQD N + ++ +L+ E K E+ +L E R ++ +
Sbjct: 447 ELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 506
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
T E + Q ++ +K + E ++ + LT T+ + + Q Q+ +QL +K
Sbjct: 507 RTAEHEAAQ-QDLQSKFVAKENEVQSLHSKLTDTL-VSKQQLEQRLMQLMESEQKRVNKE 564
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
++ ++ +++Q ++L+A++ + QI T A ++L + + + + +++ +
Sbjct: 565 ESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA-EELHKVIAEKDKQIKQTEDSL 623
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET-L 455
E + E EL+D +N L+A++ +L+ + N E++ + K+ +
Sbjct: 624 ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQ-ALANEQAAAAHELEKMQQSVYVKDDKI 682
Query: 456 RVTEDEVTTCKREKESENKIGIQQK--LAAELLNKEEIIGKMQIQ--TRELIKNIKLNEQ 511
R+ E+++ K E KI Q L +E+ + ++ + + ++ K I+ ++
Sbjct: 683 RLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDE 742
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLDVVHRN---EEL 566
K+ E+ L+ +A +E N I ++ L +E+ DLK K D V EEL
Sbjct: 743 KLKTVEEL---LETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEEL 799
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIV 626
+++ +KD +++ ++ + + +E+ + LK + E+ +Q + ++ I
Sbjct: 800 KKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSIT 859
Query: 627 DEVNK 631
+V +
Sbjct: 860 SKVQE 864
Score = 60.5 bits (140), Expect = 2e-08
Identities = 84/454 (18%), Positives = 200/454 (44%), Gaps = 36/454 (7%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKA----------LEEMRHELDEERTAKLAI 272
REV L + + + ++L++E++ A L+ M DE +
Sbjct: 249 REVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLL 308
Query: 273 KEKLTTTESQLRQT-RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
KEK + L+++ + + + QL+E + + ++ +D+ +Q ++ +
Sbjct: 309 KEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQEMMTEKER 368
Query: 332 LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED---LKQTKRA 388
+ + L ++ + Q ++ Q+ +++ ++ + +Q+E + LKQ
Sbjct: 369 SNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGI 428
Query: 389 LQEQCEITKREIELKERTETEL--QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
L++ T ++E K+ E QD + EL K +L++ + + L
Sbjct: 429 LRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKV 488
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
+LQ + +EV + R++ +E++ QQ L ++ + KE + + + + + +
Sbjct: 489 QLQEAERRW----EEVQSYIRKRTAEHEAA-QQDLQSKFVAKENEVQSLHSKLTDTLVSK 543
Query: 507 KLNEQKVIQY----EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+ EQ+++Q ++ V ++ + + E + Q +QQ + + V
Sbjct: 544 QQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQ-IQQFHSQIAAQTSASVLA 602
Query: 563 NEELSEILAKKDQELEQ-QDKNSRGQARVIKIREEL-----INVLKNKETEQSRELAALQ 616
EEL +++A+KD++++Q +D + + R+ EEL +N L E ++ + LA Q
Sbjct: 603 -EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQ 661
Query: 617 QDLEHRMRIVDEVNKQIAAKADEIQELFATLENK 650
H + +++ + + K D+I+ L L+++
Sbjct: 662 AAAAHEL---EKMQQSVYVKDDKIRLLEEQLQHE 692
>AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 720
Score = 72.5 bits (170), Expect = 5e-12
Identities = 103/465 (22%), Positives = 207/465 (44%), Gaps = 42/465 (9%)
Query: 229 RQDVETRNVMIDEIRELRS-----ESENTKALEEMRHELDEERTAKLAIKEKLTTT---E 280
+Q + R ++ I ELR+ E+EN+ M H + + + + EK + + E
Sbjct: 231 KQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLE 290
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
S++ + +++ ++KQL E + +S+ LE Q E QLE + ++ +E KT
Sbjct: 291 SEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELE-QELMLEAQLEKKDQQFKEQEKTMS 349
Query: 341 VTTSQLIQQR---DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCE 394
+ +I ++ +SL + E K +++K ++ A++ L+ + + R L E
Sbjct: 350 MLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALE 409
Query: 395 ITKREIEL--------KERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
I K E+ L KE+ E +L+ + LQ EL+ + +E+ + L
Sbjct: 410 ICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQK---ELKIKNHSLQETSEQNVILQH 466
Query: 447 ELQATK-----ETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRE 501
LQ + ET+R E E T K EK+ ++Q+L + + E + KM+ +
Sbjct: 467 TLQQQQQMLQQETIRNGELEDTQTKLEKQVSK---LEQELQKQRESSAEKLRKMEEKCES 523
Query: 502 LIKNIKLNEQKVIQYEQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
L QKVI+ R ++ ++ + I + E + + LD++
Sbjct: 524 AAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMI 583
Query: 561 HRNEELSEILAKKD--QELEQQDKNSRGQ-ARVIKIREELINVLKNKETEQS---RELAA 614
++ +E+ K + +ELE+ ++ + ++ RE L L+N E R+L
Sbjct: 584 -LDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQE 642
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
L+ L+ ++E I E++E +E+K+Q++ +++
Sbjct: 643 LRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQ 687
Score = 62.9 bits (146), Expect = 4e-09
Identities = 82/428 (19%), Positives = 189/428 (44%), Gaps = 35/428 (8%)
Query: 173 SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDV 232
S+ + + C L L+ Q E+ + + ++ + + L+ + L ++ + ++
Sbjct: 287 SKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMLEAQ-LEKKDQQFKEQE 345
Query: 233 ETRNVMIDEIRELRSESENT-KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
+T +++ +I + E+ + L E + E+ +E K E L ++Q+ + +V
Sbjct: 346 KTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKK---DEALKALQNQVSEETIKVR 402
Query: 292 KMDKQLR----EAEASITSLTGTVKMLEDQSRQK-------EVQLEARARKLRESLKTGE 340
++D L E + L G + E Q ++K + +L+ + L+E+ +
Sbjct: 403 QLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNV 462
Query: 341 VTTSQLIQQRDSLQAEVL------ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
+ L QQ+ LQ E + + + ++EK + + +Q+ E + R ++E+CE
Sbjct: 463 ILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE 522
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET 454
E +LK + EL + ++ IE+++ K E+EI + + +
Sbjct: 523 SAAHEADLKRQKVIELTGTARQVK------IEMDQYKEELS-KMEKEI-MHLKRDGENKA 574
Query: 455 LRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI 514
+ +++ ++ + + E E K ++L +L + E +Q RE+++ N
Sbjct: 575 MHLSQLDMILDQTKTELEKKTNAVKEL-EKLQHSTETELTEALQKREVLETELQNAHG-- 631
Query: 515 QYEQYVRDLQAHNRTIANCQES--PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK 572
+ + +R LQ + Q S + +DL E+ + KM++ D E+ + L +
Sbjct: 632 ELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKE 691
Query: 573 KDQELEQQ 580
++ EL+Q+
Sbjct: 692 RNWELKQR 699
Score = 43.6 bits (98), Expect = 0.002
Identities = 57/316 (18%), Positives = 142/316 (44%), Gaps = 19/316 (6%)
Query: 383 KQTKRALQEQCEITKREIE-LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
K+ KR LQE+C + K E+E LKE+ +++ N E+L +I+ ++ S+ L R+
Sbjct: 2 KENKR-LQERCGLYKSELEILKEKLRQLKEENNNGKEKL--RIMAVKNSEVMAQLTESRQ 58
Query: 442 --IDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQT 499
+ L +EL+ E LR D+ + +E + ++ Q + +L +E ++++++
Sbjct: 59 SILKLESELENKDEILR---DKFSLMNENRELKVRVAAQNE-RLDLCQQEIESSRVELRS 114
Query: 500 RELIKNIKLNEQKVIQYEQYVRDLQ------AHNRTIANCQESPNGISYQDLQQEIMDLK 553
E I + ++++ ++ Y+ Q +R I C+ + IS ++ I + +
Sbjct: 115 LEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAE 174
Query: 554 MKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELA 613
++ L +LS+ L + + ++ K S + +K+ + +K++ +
Sbjct: 175 IQKLHANLTANQLSQSLITCN-DSQESSKLSSLETEPVKLGGHQVESVKDQNQHTMNK-- 231
Query: 614 ALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXX 673
+++ + + ++E+ ++ E +L + ++ Q +++ +L
Sbjct: 232 QYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLES 291
Query: 674 XXXXXXXKIAALEHEL 689
++ LE +L
Sbjct: 292 EMTKKCSQLLTLEKQL 307
Score = 41.1 bits (92), Expect = 0.013
Identities = 60/326 (18%), Positives = 136/326 (41%), Gaps = 21/326 (6%)
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
++ L+ ++ + + +LT + + +I +LE +L+ L+++ + ELK R +
Sbjct: 36 KEKLRIMAVKNSEVMAQLT-ESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQ 94
Query: 410 LQDSRNAIEELQAKIIELEK-SKPNPDLPTEREIDLWAELQATKETLRVTEDE---VTTC 465
+ +E+++ +EL K LP +RE+ + + + + E + C
Sbjct: 95 NERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCC 154
Query: 466 KREKESENKIGIQQKL-AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQ 524
+ K +++ I+ + AE+ + Q+ + N K+ E L
Sbjct: 155 EANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLG 214
Query: 525 AHN-RTIANCQESPNGISYQDLQQEIM----DLKMKLLDVVHRNEELSEILAKKDQELEQ 579
H ++ + + Y+ +Q ++ +L+ KL+ + N +L +A + + +
Sbjct: 215 GHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQL 274
Query: 580 -QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKAD 638
Q++ + K+ E+ T++ +L L++ LE ++ + + A
Sbjct: 275 IQEELLEKASNSSKLESEM--------TKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQ 326
Query: 639 EIQELFATLENKQQQIHRLEKIVLAL 664
E+ L A LE K QQ EK + L
Sbjct: 327 ELM-LEAQLEKKDQQFKEQEKTMSML 351
Score = 41.1 bits (92), Expect = 0.013
Identities = 42/193 (21%), Positives = 93/193 (48%), Gaps = 30/193 (15%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
EL G R++K + + ++ + K H +R GE +++L ++++D
Sbjct: 537 ELTGTARQVKIEMDQYKEELSKMEKEIMHLKRD----GENKAMHLSQL-------DMILD 585
Query: 241 EIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLTT----TESQLRQTRNRVAKMDK 295
+ + EL ++ K LE+++H + E T L +E L T +L+ T ++ ++
Sbjct: 586 QTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRD 645
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
L++A+ S+ T+K L + R+ ++++E + ++L E Q +++R+
Sbjct: 646 VLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEM--------DQALKERN---- 693
Query: 356 EVLECKQQIEKLT 368
E KQ+ ++T
Sbjct: 694 --WELKQRAAQVT 704
Score = 33.9 bits (74), Expect = 2.0
Identities = 34/144 (23%), Positives = 62/144 (43%), Gaps = 8/144 (5%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV-REVAKLRQDVETRNVMIDEIRE 244
L + KT+ E N V +L K H T + EAL REV + E +N +
Sbjct: 584 LDQTKTELEKKTNAVKELEKLQ-HSTETELT--EALQKREVL----ETELQNAHGELKST 636
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
LR E L++ + L+E+ T + +L + ++ + + +MD+ L+E +
Sbjct: 637 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL 696
Query: 305 TSLTGTVKMLEDQSRQKEVQLEAR 328
V L+ R+ ++E +
Sbjct: 697 KQRAAQVTHLDMTIREHRGEMEQK 720
>BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 72.1 bits (169), Expect = 6e-12
Identities = 106/543 (19%), Positives = 260/543 (47%), Gaps = 55/543 (10%)
Query: 147 ENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV----NTVTD 202
E ++ K + Q D + L + ++ +++ + + + +A++ + + +
Sbjct: 70 EIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVN 129
Query: 203 LSKRACHERRTLIAVGE-ALVREVAKLRQDV-ETRNVMIDEIRELR-SESENTKALEEMR 259
L+K E+ + +++ + + +R++ + +++V + R+ ++ E+ +LR S ++ T+ +E
Sbjct: 130 LTKLV--EQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETE 187
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR 319
+E A ++++ +++ + + K++K+L++ +A + S +K L+ +
Sbjct: 188 RSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQ 247
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQL--IQQRDS-LQAEVLECKQQIEKLTVQHKSAIQ 376
+ + +L+ ++L+E E +L Q R++ LQ E + E+L+ +++
Sbjct: 248 KSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKAL 307
Query: 377 QL---EEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKII----ELEK 429
+L EE++ Q + + + +I ++ + TE + + E L+ +I+ E+E
Sbjct: 308 ELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEA 367
Query: 430 SKPNPDLPTE------REIDLWAE--LQATKETLRVTE--DEVTTCKREKESE-----NK 474
SK +L + RE D+ + L+A T + T+ KR E E ++
Sbjct: 368 SKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDE 427
Query: 475 IGIQQKLAAEL-LNKEEIIGKMQIQTRELIKN---IKLNEQKVIQYEQYVRDLQAHNRTI 530
Q+K+ L ++ I + T++++ N IK+ E ++ Y + + + + +
Sbjct: 428 AQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQ 487
Query: 531 ANCQE---SPNGISYQDL---QQEIMDLKMKLLDVVHRNEELSEILAKKDQ-----ELEQ 579
N E S + ++L Q EI D+K KL ++H+ +EL E ++ K+ LEQ
Sbjct: 488 QNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQ 547
Query: 580 Q--DKNSRG-QARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI 633
Q +K +A + K+R++ + + ++ +E E+ + L + + R+R E+++ I
Sbjct: 548 QRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVI 607
Query: 634 AAK 636
+ +
Sbjct: 608 SER 610
Score = 50.4 bits (115), Expect = 2e-05
Identities = 96/479 (20%), Positives = 211/479 (44%), Gaps = 58/479 (12%)
Query: 226 AKLRQDVETRNVMIDEI-RELRSESENTKALEEMRHE--LDEERTAKLA--IKEKLTTTE 280
AKL+Q+ E +++ +++ +E + ++ KA EE H+ LD + K+ I +KL TE
Sbjct: 282 AKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTE 341
Query: 281 SQLRQTRNRVAKMDKQL----REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
Q + + Q+ RE EAS K +++ R++++ + + + +
Sbjct: 342 DQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQ 401
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
K ++ Q + +L+ E+ K + +K + I LE K+ R + + ++T
Sbjct: 402 KQTDLVKLHE-QAKRNLEGEIQNYKDEAQK----QRKIIFHLE---KERDRYINQASDLT 453
Query: 397 KREI----ELKERTETELQDSRNAIEELQAKIIE----LEKSKPNPDLPTEREIDLWAEL 448
++ + ++K R ET++ D R I E + K+ + E + + +L ++ ++ E+
Sbjct: 454 QKVLMNMEDIKVR-ETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEI 512
Query: 449 QATKETLRVTEDEVTTCKR-------------------EKESENKIGIQQKLAAELLNKE 489
K L++ +V K EKE E QKL + L +
Sbjct: 513 TDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETK 572
Query: 490 EIIGKMQIQTRELIKNI------KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
I K + + R+L++ I +L ++K + RD+ N + + + Y+
Sbjct: 573 HFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELA---LLYE 629
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN 603
++ + L R E++ + + + ++ +R A V ++R+E ++ +
Sbjct: 630 KIKIQQSVLNKGESQYNQRLEDMRILRLEIKKLRREKGILARSMANVEELRQEFFHMQRE 689
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ-IHRLEKIV 661
E++R AL+++LE+ + + +++ A EL + Q++ I + E++V
Sbjct: 690 LLKERTR-CRALEEELENPLNV--HRWRKLEASDPNAYELIQKIHTLQKRLISKTEEVV 745
Score = 49.2 bits (112), Expect = 5e-05
Identities = 75/364 (20%), Positives = 161/364 (44%), Gaps = 28/364 (7%)
Query: 294 DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL--KTGEVTTSQLIQQRD 351
DK L + L +K +S E +L A+ R+L + + +V T+ + Q D
Sbjct: 33 DKSLEKFRIEYERLHAVMK----KSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDD 88
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE----LKERTE 407
Q + K++IEK SA + E+ K+T AL+E+ + +E L
Sbjct: 89 --QTTIASLKKEIEKAWKMVDSAYDK-EQKAKETILALKEEIVNLTKLVEQGSGLSMDQH 145
Query: 408 TELQDSRNAIEELQAK----IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
+ ++D EE+ + + E+ K + + TE++ + + + + + E+
Sbjct: 146 SNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQ 205
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+R+ E+ + ++KL EL + + Q + + L + ++ +++++ + EQ +++
Sbjct: 206 --QRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQ 263
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
+ N A E + LQQE + + N++ + L K++E+ Q +
Sbjct: 264 KILNERAAKELEQFQ-MRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRM----RIVDEVNKQIAAKADE 639
++ KIRE++ L + E +Q E+ ++ L++++ R V+ KQ
Sbjct: 323 I---GKLNKIREQIHKKLHHTE-DQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKA 378
Query: 640 IQEL 643
+ EL
Sbjct: 379 MDEL 382
Score = 40.3 bits (90), Expect = 0.023
Identities = 64/296 (21%), Positives = 130/296 (43%), Gaps = 24/296 (8%)
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
V +SA +++E D + L + K IE ER ++ S + + L AK EL
Sbjct: 10 VLEESAFEEMERDFQGVLHELSGDKSLEKFRIEY-ERLHAVMKKSYDNEKRLMAKCRELN 68
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
EI + + AT L++++D+ TT K+ K K+ +K
Sbjct: 69 A-----------EIVVNSAKVAT--ALKLSQDDQTTIASLKKEIEKAW---KMVDSAYDK 112
Query: 489 EEIIGKMQIQTRELIKNI-KLNEQ-KVIQYEQY--VRDLQAHNRTIANCQESPNGISYQD 544
E+ + + +E I N+ KL EQ + +Q+ +RDL + ++
Sbjct: 113 EQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLS-EVVK 171
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKN 603
L++ + + + EE +++ QE++Q Q++ SR + K+ +EL + +
Sbjct: 172 LRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQAD 231
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
++ Q+ E+ ALQQ ++ + ++ +Q+ + + LE Q + +L++
Sbjct: 232 MDSRQT-EIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQ 286
>BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 72.1 bits (169), Expect = 6e-12
Identities = 106/543 (19%), Positives = 260/543 (47%), Gaps = 55/543 (10%)
Query: 147 ENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV----NTVTD 202
E ++ K + Q D + L + ++ +++ + + + +A++ + + +
Sbjct: 70 EIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVN 129
Query: 203 LSKRACHERRTLIAVGE-ALVREVAKLRQDV-ETRNVMIDEIRELR-SESENTKALEEMR 259
L+K E+ + +++ + + +R++ + +++V + R+ ++ E+ +LR S ++ T+ +E
Sbjct: 130 LTKLV--EQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETE 187
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR 319
+E A ++++ +++ + + K++K+L++ +A + S +K L+ +
Sbjct: 188 RSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQ 247
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQL--IQQRDS-LQAEVLECKQQIEKLTVQHKSAIQ 376
+ + +L+ ++L+E E +L Q R++ LQ E + E+L+ +++
Sbjct: 248 KSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKAL 307
Query: 377 QL---EEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKII----ELEK 429
+L EE++ Q + + + +I ++ + TE + + E L+ +I+ E+E
Sbjct: 308 ELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEA 367
Query: 430 SKPNPDLPTE------REIDLWAE--LQATKETLRVTE--DEVTTCKREKESE-----NK 474
SK +L + RE D+ + L+A T + T+ KR E E ++
Sbjct: 368 SKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDE 427
Query: 475 IGIQQKLAAEL-LNKEEIIGKMQIQTRELIKN---IKLNEQKVIQYEQYVRDLQAHNRTI 530
Q+K+ L ++ I + T++++ N IK+ E ++ Y + + + + +
Sbjct: 428 AQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQ 487
Query: 531 ANCQE---SPNGISYQDL---QQEIMDLKMKLLDVVHRNEELSEILAKKDQ-----ELEQ 579
N E S + ++L Q EI D+K KL ++H+ +EL E ++ K+ LEQ
Sbjct: 488 QNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQ 547
Query: 580 Q--DKNSRG-QARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI 633
Q +K +A + K+R++ + + ++ +E E+ + L + + R+R E+++ I
Sbjct: 548 QRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVI 607
Query: 634 AAK 636
+ +
Sbjct: 608 SER 610
Score = 50.4 bits (115), Expect = 2e-05
Identities = 96/479 (20%), Positives = 211/479 (44%), Gaps = 58/479 (12%)
Query: 226 AKLRQDVETRNVMIDEI-RELRSESENTKALEEMRHE--LDEERTAKLA--IKEKLTTTE 280
AKL+Q+ E +++ +++ +E + ++ KA EE H+ LD + K+ I +KL TE
Sbjct: 282 AKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTE 341
Query: 281 SQLRQTRNRVAKMDKQL----REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
Q + + Q+ RE EAS K +++ R++++ + + + +
Sbjct: 342 DQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQ 401
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
K ++ Q + +L+ E+ K + +K + I LE K+ R + + ++T
Sbjct: 402 KQTDLVKLHE-QAKRNLEGEIQNYKDEAQK----QRKIIFHLE---KERDRYINQASDLT 453
Query: 397 KREI----ELKERTETELQDSRNAIEELQAKIIE----LEKSKPNPDLPTEREIDLWAEL 448
++ + ++K R ET++ D R I E + K+ + E + + +L ++ ++ E+
Sbjct: 454 QKVLMNMEDIKVR-ETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEI 512
Query: 449 QATKETLRVTEDEVTTCKR-------------------EKESENKIGIQQKLAAELLNKE 489
K L++ +V K EKE E QKL + L +
Sbjct: 513 TDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETK 572
Query: 490 EIIGKMQIQTRELIKNI------KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
I K + + R+L++ I +L ++K + RD+ N + + + Y+
Sbjct: 573 HFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELA---LLYE 629
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN 603
++ + L R E++ + + + ++ +R A V ++R+E ++ +
Sbjct: 630 KIKIQQSVLNKGESQYNQRLEDMRILRLEIKKLRREKGILARSMANVEELRQEFFHMQRE 689
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ-IHRLEKIV 661
E++R AL+++LE+ + + +++ A EL + Q++ I + E++V
Sbjct: 690 LLKERTR-CRALEEELENPLNV--HRWRKLEASDPNAYELIQKIHTLQKRLISKTEEVV 745
Score = 49.2 bits (112), Expect = 5e-05
Identities = 75/364 (20%), Positives = 161/364 (44%), Gaps = 28/364 (7%)
Query: 294 DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL--KTGEVTTSQLIQQRD 351
DK L + L +K +S E +L A+ R+L + + +V T+ + Q D
Sbjct: 33 DKSLEKFRIEYERLHAVMK----KSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDD 88
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE----LKERTE 407
Q + K++IEK SA + E+ K+T AL+E+ + +E L
Sbjct: 89 --QTTIASLKKEIEKAWKMVDSAYDK-EQKAKETILALKEEIVNLTKLVEQGSGLSMDQH 145
Query: 408 TELQDSRNAIEELQAK----IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
+ ++D EE+ + + E+ K + + TE++ + + + + + E+
Sbjct: 146 SNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQ 205
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+R+ E+ + ++KL EL + + Q + + L + ++ +++++ + EQ +++
Sbjct: 206 --QRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQ 263
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
+ N A E + LQQE + + N++ + L K++E+ Q +
Sbjct: 264 KILNERAAKELEQFQ-MRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRM----RIVDEVNKQIAAKADE 639
++ KIRE++ L + E +Q E+ ++ L++++ R V+ KQ
Sbjct: 323 I---GKLNKIREQIHKKLHHTE-DQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKA 378
Query: 640 IQEL 643
+ EL
Sbjct: 379 MDEL 382
Score = 40.3 bits (90), Expect = 0.023
Identities = 64/296 (21%), Positives = 130/296 (43%), Gaps = 24/296 (8%)
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
V +SA +++E D + L + K IE ER ++ S + + L AK EL
Sbjct: 10 VLEESAFEEMERDFQGVLHELSGDKSLEKFRIEY-ERLHAVMKKSYDNEKRLMAKCRELN 68
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
EI + + AT L++++D+ TT K+ K K+ +K
Sbjct: 69 A-----------EIVVNSAKVAT--ALKLSQDDQTTIASLKKEIEKAW---KMVDSAYDK 112
Query: 489 EEIIGKMQIQTRELIKNI-KLNEQ-KVIQYEQY--VRDLQAHNRTIANCQESPNGISYQD 544
E+ + + +E I N+ KL EQ + +Q+ +RDL + ++
Sbjct: 113 EQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLS-EVVK 171
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKN 603
L++ + + + EE +++ QE++Q Q++ SR + K+ +EL + +
Sbjct: 172 LRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQAD 231
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
++ Q+ E+ ALQQ ++ + ++ +Q+ + + LE Q + +L++
Sbjct: 232 MDSRQT-EIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQ 286
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 72.1 bits (169), Expect = 6e-12
Identities = 101/501 (20%), Positives = 224/501 (44%), Gaps = 43/501 (8%)
Query: 192 QAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESEN 251
+ +D+ + + + R + V L ++ +L+ R+++ ++ +E +
Sbjct: 457 ELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSS 516
Query: 252 TK-ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNR-----VAKMDKQLREAEASIT 305
K +LE+ R E+ +E L + + +L++ + + V +M + + E +
Sbjct: 517 LKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLV 576
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
S + E + R+ + E RK E +L++ +D + EV E + +E
Sbjct: 577 SARRRSDLYESELRESRLAAEEFKRKATEC-------QHKLLKAKDQGKPEVGEYAK-LE 628
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE---LQDSRNAIEELQA 422
K+ + + IQ+L+E L++ +A E E+ + + KER E E LQ+ ++ E ++
Sbjct: 629 KINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRK 688
Query: 423 KIIELEKSKPNPD-----LPT--EREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
K++E E+ + + + L T RE L ++Q + ++ D++ + EK E ++
Sbjct: 689 KLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSQQIQQMADKILELE-EKHREAQV 747
Query: 476 GIQQKLAAELLNKEE-IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ 534
Q L L KE+ K+++ ++ K++ E +++ + + ++ +
Sbjct: 748 SAQH-LEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQK 806
Query: 535 ESPNGI--SYQDLQQEIMDLK--MKLLD----VVHRNEELSE--ILAKKDQELEQQDKNS 584
N + + L+Q I++L KL RN + E I + Q+ + +
Sbjct: 807 AMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAG 866
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD-EVNKQIAAKADEIQEL 643
+ +A+ K+ E+L + ++++R L +LE R+R V E +Q ++ EL
Sbjct: 867 KLEAQNRKLEEQLEKISHQDHSDKNRLL-----ELETRLREVSLEHEEQKLELKRQLTEL 921
Query: 644 FATLENKQQQIHRLEKIVLAL 664
+L+ ++ Q+ L+ AL
Sbjct: 922 QLSLQERESQLTALQAARAAL 942
Score = 70.1 bits (164), Expect = 2e-11
Identities = 96/500 (19%), Positives = 223/500 (44%), Gaps = 45/500 (9%)
Query: 194 EDAVNTVTDLS--KRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESEN 251
+D +T+ S KR+ + R ++ + + +L D+ ++ + EI+E +++
Sbjct: 505 QDLATYITECSSLKRSLEQARMEVSQEDD---KALQLLHDIREQSRKLQEIKEQEYQAQ- 560
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL---- 307
+EEMR +++ ++ + + ES+LR++R + ++ E + +
Sbjct: 561 ---VEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQG 617
Query: 308 ---TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
G LE + +++++++ KL +++K T L R + + ++++
Sbjct: 618 KPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKE----RAEREL 673
Query: 365 EKLTVQHKSA--IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA 422
EKL + S+ I++ + ++ + +L+ + + + + R + ++Q I+++
Sbjct: 674 EKLQNREDSSEGIRKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSQQIQQMAD 733
Query: 423 KIIELEKSKPNPDLPTER-EIDLWAELQATKETLRVTEDEVTTCKREKES-ENKIGIQQK 480
KI+ELE+ + + E+ L + Q +E ++V ++++ +KE+ EN + ++
Sbjct: 734 KILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEE 793
Query: 481 LAAE----LLNKEEIIGKMQIQTRELIKNI-KLNEQKVIQYEQYV---RDLQAHNRTIAN 532
A E L ++ +I M + R L + I +L+E + + R+++A I+
Sbjct: 794 EAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISE 853
Query: 533 CQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNE-------ELSEILAKKDQELEQQDKN 583
++ + Q L+ + L+ +L + H++ EL L + E E+Q
Sbjct: 854 LRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLE 913
Query: 584 SRGQARVIKI----REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+ Q +++ RE + L+ +L + +LE +E + + A DE
Sbjct: 914 LKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDE 973
Query: 640 IQELFATLENKQQQIHRLEK 659
IQ F L N I LE+
Sbjct: 974 IQRKFDALRNSCTVITDLEE 993
Score = 64.9 bits (151), Expect = 9e-10
Identities = 94/518 (18%), Positives = 221/518 (42%), Gaps = 38/518 (7%)
Query: 159 VNQDQTDGDILEHL-SRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACH--ERRTLI 215
+ +D D + LE++ R+ ++ E L E K + + L +R E L
Sbjct: 774 IKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLA 833
Query: 216 AVGEALVREVAKLRQDV--ETRNVMID-EIRELRSESENTKA---LEEMRHELDEERTAK 269
A + K ++++ E R E + + E++N K LE++ H+ ++
Sbjct: 834 ANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRL 893
Query: 270 LAIKEKLTTT----ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQL 325
L ++ +L E Q + + ++ ++ L+E E+ +T+L LE Q RQ + +L
Sbjct: 894 LELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTEL 953
Query: 326 EARARKLRESLKTGEVTTSQLIQQRDSLQ---AEVLECKQQIEKLTVQHKSAIQQ---LE 379
E + E ++ ++ ++ D+L+ + + ++Q+ +LT + Q L
Sbjct: 954 EETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLS 1013
Query: 380 EDLKQTKRALQE-----------QCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
+ L + A E + EIT+RE++L + +T ++ + L+ ++++LE
Sbjct: 1014 KQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQT-MEALKTTCTMLEEQVMDLE 1072
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
+ + L ER+ + W + +++ + E +++ Q++
Sbjct: 1073 -ALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVV 1131
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE 548
E + + + + L + +K + K + DL+ + + N S Q +
Sbjct: 1132 ELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAML-----EMNARSLQQKLET 1186
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI-REELINVLKNKETE 607
+LK +LL+ + ++ ++ L Q + + +A ++K R +L L+N +
Sbjct: 1187 ERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVL 1246
Query: 608 QSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
S E ++ + + +++D + ++ A + + LF+
Sbjct: 1247 YSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFS 1284
Score = 34.3 bits (75), Expect = 1.5
Identities = 53/278 (19%), Positives = 121/278 (43%), Gaps = 21/278 (7%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
AL+ T E+ V + L+ + R A L E ++ V M+D ++
Sbjct: 1056 ALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQ 1115
Query: 245 LRSESEN--TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
R+ ++ T++ + + + E + LA+++ L + + +++ ++K+ E
Sbjct: 1116 SRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEM 1175
Query: 303 SITSLTGTV--------KMLEDQSR-QKEVQLEAR-----ARKLRESLKTGEVTT---SQ 345
+ SL + ++LE+Q++ Q+++ L+ + L+E+L ++ S
Sbjct: 1176 NARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSD 1235
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
L Q +++Q K ++E Q I L+ + Q + + K + L +
Sbjct: 1236 LEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQ 1295
Query: 406 TETELQDSRNAIEELQAKIIELEKS--KPNPDLPTERE 441
+ + + A+E+ +A+ ELE++ K +L + RE
Sbjct: 1296 VPLQYNELKLALEKEKARCAELEEALQKTRIELRSARE 1333
>AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 72.1 bits (169), Expect = 6e-12
Identities = 106/543 (19%), Positives = 260/543 (47%), Gaps = 55/543 (10%)
Query: 147 ENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV----NTVTD 202
E ++ K + Q D + L + ++ +++ + + + +A++ + + +
Sbjct: 70 EIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVN 129
Query: 203 LSKRACHERRTLIAVGE-ALVREVAKLRQDV-ETRNVMIDEIRELR-SESENTKALEEMR 259
L+K E+ + +++ + + +R++ + +++V + R+ ++ E+ +LR S ++ T+ +E
Sbjct: 130 LTKLV--EQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETE 187
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR 319
+E A ++++ +++ + + K++K+L++ +A + S +K L+ +
Sbjct: 188 RSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQ 247
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQL--IQQRDS-LQAEVLECKQQIEKLTVQHKSAIQ 376
+ + +L+ ++L+E E +L Q R++ LQ E + E+L+ +++
Sbjct: 248 KSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKAL 307
Query: 377 QL---EEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKII----ELEK 429
+L EE++ Q + + + +I ++ + TE + + E L+ +I+ E+E
Sbjct: 308 ELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEA 367
Query: 430 SKPNPDLPTE------REIDLWAE--LQATKETLRVTE--DEVTTCKREKESE-----NK 474
SK +L + RE D+ + L+A T + T+ KR E E ++
Sbjct: 368 SKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDE 427
Query: 475 IGIQQKLAAEL-LNKEEIIGKMQIQTRELIKN---IKLNEQKVIQYEQYVRDLQAHNRTI 530
Q+K+ L ++ I + T++++ N IK+ E ++ Y + + + + +
Sbjct: 428 AQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQ 487
Query: 531 ANCQE---SPNGISYQDL---QQEIMDLKMKLLDVVHRNEELSEILAKKDQ-----ELEQ 579
N E S + ++L Q EI D+K KL ++H+ +EL E ++ K+ LEQ
Sbjct: 488 QNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQ 547
Query: 580 Q--DKNSRG-QARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI 633
Q +K +A + K+R++ + + ++ +E E+ + L + + R+R E+++ I
Sbjct: 548 QRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVI 607
Query: 634 AAK 636
+ +
Sbjct: 608 SER 610
Score = 50.4 bits (115), Expect = 2e-05
Identities = 96/479 (20%), Positives = 211/479 (44%), Gaps = 58/479 (12%)
Query: 226 AKLRQDVETRNVMIDEI-RELRSESENTKALEEMRHE--LDEERTAKLA--IKEKLTTTE 280
AKL+Q+ E +++ +++ +E + ++ KA EE H+ LD + K+ I +KL TE
Sbjct: 282 AKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTE 341
Query: 281 SQLRQTRNRVAKMDKQL----REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
Q + + Q+ RE EAS K +++ R++++ + + + +
Sbjct: 342 DQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQ 401
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
K ++ Q + +L+ E+ K + +K + I LE K+ R + + ++T
Sbjct: 402 KQTDLVKLHE-QAKRNLEGEIQNYKDEAQK----QRKIIFHLE---KERDRYINQASDLT 453
Query: 397 KREI----ELKERTETELQDSRNAIEELQAKIIE----LEKSKPNPDLPTEREIDLWAEL 448
++ + ++K R ET++ D R I E + K+ + E + + +L ++ ++ E+
Sbjct: 454 QKVLMNMEDIKVR-ETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEI 512
Query: 449 QATKETLRVTEDEVTTCKR-------------------EKESENKIGIQQKLAAELLNKE 489
K L++ +V K EKE E QKL + L +
Sbjct: 513 TDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETK 572
Query: 490 EIIGKMQIQTRELIKNI------KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
I K + + R+L++ I +L ++K + RD+ N + + + Y+
Sbjct: 573 HFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELA---LLYE 629
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN 603
++ + L R E++ + + + ++ +R A V ++R+E ++ +
Sbjct: 630 KIKIQQSVLNKGESQYNQRLEDMRILRLEIKKLRREKGILARSMANVEELRQEFFHMQRE 689
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ-IHRLEKIV 661
E++R AL+++LE+ + + +++ A EL + Q++ I + E++V
Sbjct: 690 LLKERTR-CRALEEELENPLNV--HRWRKLEASDPNAYELIQKIHTLQKRLISKTEEVV 745
Score = 49.2 bits (112), Expect = 5e-05
Identities = 75/364 (20%), Positives = 161/364 (44%), Gaps = 28/364 (7%)
Query: 294 DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL--KTGEVTTSQLIQQRD 351
DK L + L +K +S E +L A+ R+L + + +V T+ + Q D
Sbjct: 33 DKSLEKFRIEYERLHAVMK----KSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDD 88
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE----LKERTE 407
Q + K++IEK SA + E+ K+T AL+E+ + +E L
Sbjct: 89 --QTTIASLKKEIEKAWKMVDSAYDK-EQKAKETILALKEEIVNLTKLVEQGSGLSMDQH 145
Query: 408 TELQDSRNAIEELQAK----IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
+ ++D EE+ + + E+ K + + TE++ + + + + + E+
Sbjct: 146 SNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQ 205
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+R+ E+ + ++KL EL + + Q + + L + ++ +++++ + EQ +++
Sbjct: 206 --QRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQ 263
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
+ N A E + LQQE + + N++ + L K++E+ Q +
Sbjct: 264 KILNERAAKELEQFQ-MRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRM----RIVDEVNKQIAAKADE 639
++ KIRE++ L + E +Q E+ ++ L++++ R V+ KQ
Sbjct: 323 I---GKLNKIREQIHKKLHHTE-DQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKA 378
Query: 640 IQEL 643
+ EL
Sbjct: 379 MDEL 382
Score = 40.3 bits (90), Expect = 0.023
Identities = 64/296 (21%), Positives = 130/296 (43%), Gaps = 24/296 (8%)
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
V +SA +++E D + L + K IE ER ++ S + + L AK EL
Sbjct: 10 VLEESAFEEMERDFQGVLHELSGDKSLEKFRIEY-ERLHAVMKKSYDNEKRLMAKCRELN 68
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
EI + + AT L++++D+ TT K+ K K+ +K
Sbjct: 69 A-----------EIVVNSAKVAT--ALKLSQDDQTTIASLKKEIEKAW---KMVDSAYDK 112
Query: 489 EEIIGKMQIQTRELIKNI-KLNEQ-KVIQYEQY--VRDLQAHNRTIANCQESPNGISYQD 544
E+ + + +E I N+ KL EQ + +Q+ +RDL + ++
Sbjct: 113 EQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLS-EVVK 171
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKN 603
L++ + + + EE +++ QE++Q Q++ SR + K+ +EL + +
Sbjct: 172 LRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQAD 231
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
++ Q+ E+ ALQQ ++ + ++ +Q+ + + LE Q + +L++
Sbjct: 232 MDSRQT-EIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQ 286
>AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 72.1 bits (169), Expect = 6e-12
Identities = 106/543 (19%), Positives = 260/543 (47%), Gaps = 55/543 (10%)
Query: 147 ENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV----NTVTD 202
E ++ K + Q D + L + ++ +++ + + + +A++ + + +
Sbjct: 70 EIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVN 129
Query: 203 LSKRACHERRTLIAVGE-ALVREVAKLRQDV-ETRNVMIDEIRELR-SESENTKALEEMR 259
L+K E+ + +++ + + +R++ + +++V + R+ ++ E+ +LR S ++ T+ +E
Sbjct: 130 LTKLV--EQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETE 187
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR 319
+E A ++++ +++ + + K++K+L++ +A + S +K L+ +
Sbjct: 188 RSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQ 247
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQL--IQQRDS-LQAEVLECKQQIEKLTVQHKSAIQ 376
+ + +L+ ++L+E E +L Q R++ LQ E + E+L+ +++
Sbjct: 248 KSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKAL 307
Query: 377 QL---EEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKII----ELEK 429
+L EE++ Q + + + +I ++ + TE + + E L+ +I+ E+E
Sbjct: 308 ELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEA 367
Query: 430 SKPNPDLPTE------REIDLWAE--LQATKETLRVTE--DEVTTCKREKESE-----NK 474
SK +L + RE D+ + L+A T + T+ KR E E ++
Sbjct: 368 SKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDE 427
Query: 475 IGIQQKLAAEL-LNKEEIIGKMQIQTRELIKN---IKLNEQKVIQYEQYVRDLQAHNRTI 530
Q+K+ L ++ I + T++++ N IK+ E ++ Y + + + + +
Sbjct: 428 AQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQ 487
Query: 531 ANCQE---SPNGISYQDL---QQEIMDLKMKLLDVVHRNEELSEILAKKDQ-----ELEQ 579
N E S + ++L Q EI D+K KL ++H+ +EL E ++ K+ LEQ
Sbjct: 488 QNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQ 547
Query: 580 Q--DKNSRG-QARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI 633
Q +K +A + K+R++ + + ++ +E E+ + L + + R+R E+++ I
Sbjct: 548 QRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVI 607
Query: 634 AAK 636
+ +
Sbjct: 608 SER 610
Score = 50.4 bits (115), Expect = 2e-05
Identities = 96/479 (20%), Positives = 211/479 (44%), Gaps = 58/479 (12%)
Query: 226 AKLRQDVETRNVMIDEI-RELRSESENTKALEEMRHE--LDEERTAKLA--IKEKLTTTE 280
AKL+Q+ E +++ +++ +E + ++ KA EE H+ LD + K+ I +KL TE
Sbjct: 282 AKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTE 341
Query: 281 SQLRQTRNRVAKMDKQL----REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
Q + + Q+ RE EAS K +++ R++++ + + + +
Sbjct: 342 DQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQ 401
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
K ++ Q + +L+ E+ K + +K + I LE K+ R + + ++T
Sbjct: 402 KQTDLVKLHE-QAKRNLEGEIQNYKDEAQK----QRKIIFHLE---KERDRYINQASDLT 453
Query: 397 KREI----ELKERTETELQDSRNAIEELQAKIIE----LEKSKPNPDLPTEREIDLWAEL 448
++ + ++K R ET++ D R I E + K+ + E + + +L ++ ++ E+
Sbjct: 454 QKVLMNMEDIKVR-ETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEI 512
Query: 449 QATKETLRVTEDEVTTCKR-------------------EKESENKIGIQQKLAAELLNKE 489
K L++ +V K EKE E QKL + L +
Sbjct: 513 TDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETK 572
Query: 490 EIIGKMQIQTRELIKNI------KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
I K + + R+L++ I +L ++K + RD+ N + + + Y+
Sbjct: 573 HFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELA---LLYE 629
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN 603
++ + L R E++ + + + ++ +R A V ++R+E ++ +
Sbjct: 630 KIKIQQSVLNKGESQYNQRLEDMRILRLEIKKLRREKGILARSMANVEELRQEFFHMQRE 689
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQ-IHRLEKIV 661
E++R AL+++LE+ + + +++ A EL + Q++ I + E++V
Sbjct: 690 LLKERTR-CRALEEELENPLNV--HRWRKLEASDPNAYELIQKIHTLQKRLISKTEEVV 745
Score = 49.2 bits (112), Expect = 5e-05
Identities = 75/364 (20%), Positives = 161/364 (44%), Gaps = 28/364 (7%)
Query: 294 DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL--KTGEVTTSQLIQQRD 351
DK L + L +K +S E +L A+ R+L + + +V T+ + Q D
Sbjct: 33 DKSLEKFRIEYERLHAVMK----KSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDD 88
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE----LKERTE 407
Q + K++IEK SA + E+ K+T AL+E+ + +E L
Sbjct: 89 --QTTIASLKKEIEKAWKMVDSAYDK-EQKAKETILALKEEIVNLTKLVEQGSGLSMDQH 145
Query: 408 TELQDSRNAIEELQAK----IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
+ ++D EE+ + + E+ K + + TE++ + + + + + E+
Sbjct: 146 SNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQ 205
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+R+ E+ + ++KL EL + + Q + + L + ++ +++++ + EQ +++
Sbjct: 206 --QRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQ 263
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
+ N A E + LQQE + + N++ + L K++E+ Q +
Sbjct: 264 KILNERAAKELEQFQ-MRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRM----RIVDEVNKQIAAKADE 639
++ KIRE++ L + E +Q E+ ++ L++++ R V+ KQ
Sbjct: 323 I---GKLNKIREQIHKKLHHTE-DQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKA 378
Query: 640 IQEL 643
+ EL
Sbjct: 379 MDEL 382
Score = 40.3 bits (90), Expect = 0.023
Identities = 64/296 (21%), Positives = 130/296 (43%), Gaps = 24/296 (8%)
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
V +SA +++E D + L + K IE ER ++ S + + L AK EL
Sbjct: 10 VLEESAFEEMERDFQGVLHELSGDKSLEKFRIEY-ERLHAVMKKSYDNEKRLMAKCRELN 68
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
EI + + AT L++++D+ TT K+ K K+ +K
Sbjct: 69 A-----------EIVVNSAKVAT--ALKLSQDDQTTIASLKKEIEKAW---KMVDSAYDK 112
Query: 489 EEIIGKMQIQTRELIKNI-KLNEQ-KVIQYEQY--VRDLQAHNRTIANCQESPNGISYQD 544
E+ + + +E I N+ KL EQ + +Q+ +RDL + ++
Sbjct: 113 EQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLS-EVVK 171
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKN 603
L++ + + + EE +++ QE++Q Q++ SR + K+ +EL + +
Sbjct: 172 LRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQAD 231
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
++ Q+ E+ ALQQ ++ + ++ +Q+ + + LE Q + +L++
Sbjct: 232 MDSRQT-EIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQ 286
>AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluronic
acid binding protein protein.
Length = 724
Score = 72.1 bits (169), Expect = 6e-12
Identities = 95/437 (21%), Positives = 204/437 (46%), Gaps = 43/437 (9%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL-AIKEKLTTTESQLRQTRNR 289
DV+T V+ + +S+ K +E + L+ ++ L A K+ ++ES+ Q ++
Sbjct: 25 DVKTLEVLKGPVSF--QKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKESQKNDK 82
Query: 290 VAK-MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTS-QLI 347
K ++K++R + ++ LE + + E +L A R+ + SL T QLI
Sbjct: 83 DLKILEKEIRVLLQERGAQDSRIQDLETELEKMEARLNAALRE-KTSLSANNATLEKQLI 141
Query: 348 QQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKRE-IELK-ER 405
+ + E+L K + + Q I LE + KR + + + K+E +E+K +
Sbjct: 142 ELTRT--NELL--KSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQV 197
Query: 406 TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC 465
T+ L++S+ I +L+ K++ +EK K + TE+ ++ E+ + + + ++
Sbjct: 198 TQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQL 257
Query: 466 KREKESENK--IGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+ + +N + ++Q L EE I + Q +L +L E+ + E +V
Sbjct: 258 EENLKEKNDEILSLKQSL-------EENIVILSKQVEDLNVKCQLLEK---EKEDHVNRN 307
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQ-DK 582
+ HN ++L E+ +LK K + E+L + + D L+Q+ +
Sbjct: 308 REHN---------------ENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKEL 352
Query: 583 NSRGQARVIKIREELI---NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
+S ++ +EE++ N+ + + + EL LQQ E R+V ++ ++ ++A+E
Sbjct: 353 SSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEE 412
Query: 640 IQELFATLENKQQQIHR 656
++ L L+ K+ ++ +
Sbjct: 413 LKLLEEKLKGKEAELEK 429
Score = 59.3 bits (137), Expect = 5e-08
Identities = 86/385 (22%), Positives = 167/385 (43%), Gaps = 30/385 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
R+ ++ + + ID + L+ E E + +L + EE +KEK E +L+QT +
Sbjct: 332 REKLQQKELQIDSL--LQQEKELSSSLHQKLCSFQEEM-----VKEK-NLFEEELKQTLD 383
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQ 348
+ K+ ++ +AE + L K ++ + E +L+ + +L +S T L +
Sbjct: 384 ELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQE 443
Query: 349 QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTET 408
+ DS+ + + Q E S I EDLK +LQE+ + E +
Sbjct: 444 KYDSMVQSLEDVTAQFESYKALTASEI----EDLKLENSSLQEKAAKAGKN---AEDVQH 496
Query: 409 ELQDSRNAIEELQAKIIELE-KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
++ + ++ +E +++L+ KS E + ++ + L+ E++ K+
Sbjct: 497 QILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFR--KQ 554
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
++ E + ++ AEL E I K ++ EL K + +Q + + + QA
Sbjct: 555 LEDEEGRKAEKENTTAEL---TEEINKWRLLYEELYNKTKPFQ---LQLDAFEVEKQALL 608
Query: 528 RTIANCQESPNGI--SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSR 585
QE N I SY L +LK K+ VV +E S++ ++ + Q K +
Sbjct: 609 NEHGAAQEQLNKIRDSYAKLLGH-QNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQ 667
Query: 586 GQARVIKIREELINVLKNKETEQSR 610
+ K++EEL VL K + S+
Sbjct: 668 SET---KLQEELNKVLGIKHFDPSK 689
Score = 48.8 bits (111), Expect = 6e-05
Identities = 65/317 (20%), Positives = 124/317 (39%), Gaps = 10/317 (3%)
Query: 224 EVAKLRQDVETRNVMIDEIRE-LRSESENTKALEEMRHELDEERTAKLAIKEKLTTT-ES 281
E+ KL+Q E ++ ++ E +S +E K LEE + E A + T +
Sbjct: 384 ELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQE 443
Query: 282 QLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEV 341
+ + + Q +A S +K+ ++K + A ++ + E
Sbjct: 444 KYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATES 503
Query: 342 TTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE 401
+ + ++ LQ + + +I+++TV I L+ LKQ + ++Q E +
Sbjct: 504 SNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKA 563
Query: 402 LKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQ---ATKETLRVT 458
KE T EL + N L ++ K+KP E++ A L A +E L
Sbjct: 564 EKENTTAELTEEINKWRLLYEEL--YNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKI 621
Query: 459 EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQ-TRELIKNIKLNEQ--KVIQ 515
D + + KI KL E + + K++ Q ++ KL E+ KV+
Sbjct: 622 RDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLG 681
Query: 516 YEQYVRDLQAHNRTIAN 532
+ + H+ + N
Sbjct: 682 IKHFDPSKAFHHESKEN 698
>L06148-1|AAA35921.1| 579|Homo sapiens golgin-165 protein.
Length = 579
Score = 71.7 bits (168), Expect = 8e-12
Identities = 92/454 (20%), Positives = 205/454 (45%), Gaps = 23/454 (5%)
Query: 210 ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESE-NTKALEEMRHELDEERTA 268
E+RT A L REVA++RQ + + ++ R E E + ++L+ + ++ A
Sbjct: 124 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEA 183
Query: 269 KLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
A+K+++ E ++ R + + +++R + +TS K ++ + + E +
Sbjct: 184 NEALKKQI---EELQQEARKAITEQKQKMRRLGSDLTSAQ---KEMKTKHKAYENAVGIL 237
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
+R+L+E+L E ++L Q R Q + + + ++ +Q + ++
Sbjct: 238 SRRLQEALAAKEAADAELGQLR--AQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE 295
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
LQE +T +E+E EL+D + KI LE+S L E E L
Sbjct: 296 LQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGL 355
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
+ LR + T ++E++ + + ++ A L KEE +M+ + L +++
Sbjct: 356 GQSNAALREHNSILETALAKREAD-LVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEK 414
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-S 567
++KV ++ V A + N ++ E+ ++K +L H ++L +
Sbjct: 415 EKEKVNSLKEQV--------AAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQA 466
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
E + +E + + ++ QA + + R +L +L+ + EQ + Q++E+ VD
Sbjct: 467 EADDLQIREGKHSQEIAQFQAELAEARAQL-QLLQKQLDEQLSKQPVGNQEMENLKWEVD 525
Query: 628 EVNKQIAAKADEIQELFATLENKQQQIHRLEKIV 661
+ ++I + Q+L T + ++++ L++++
Sbjct: 526 QKEREIQSLK---QQLDLTEQQGRKELEGLQQLL 556
Score = 64.5 bits (150), Expect = 1e-09
Identities = 84/405 (20%), Positives = 186/405 (45%), Gaps = 34/405 (8%)
Query: 161 QDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA 220
Q + I E + G +L A +E+KT+ + N V LS+R + +A EA
Sbjct: 195 QQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRL----QEALAAKEA 250
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTE 280
E+ +LR + + + +++ +A+ + L++E ++E + T
Sbjct: 251 ADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE------LQEVIALTS 304
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+L ++R +V +++ +L+E+ +K LE+ +++ ++LE KL TG
Sbjct: 305 QELEESREKVLELEDELQESR----GFRKKIKRLEESNKKLALELEHEKGKL-----TGL 355
Query: 341 VTTSQLIQQRDS-LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEIT 396
++ +++ +S L+ + + + + +L +Q ++ +Q+ EE+ +Q K +ALQ E
Sbjct: 356 GQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKE 415
Query: 397 KREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
K ++ LKE+ ++ + +A +EL + K + + L +LQA + L
Sbjct: 416 KEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKE----LQAKEHLVQKLQAEADDL 471
Query: 456 RVTE----DEVTTCKRE-KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
++ E E+ + E E+ ++ + QK E L+K+ +G +++ + + K E
Sbjct: 472 QIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQP-VGNQEMENLKWEVDQKERE 530
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ ++ + + + Q Q N S ++ QE + + K
Sbjct: 531 IQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQK 575
Score = 48.8 bits (111), Expect = 6e-05
Identities = 85/455 (18%), Positives = 200/455 (43%), Gaps = 45/455 (9%)
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
T + L+ ++ ++D+ R E + T++ L ++ K Q+E ++
Sbjct: 7 TGDSAALQAVKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALK 66
Query: 337 KTGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHK---SAIQQLEEDLKQT---KR 387
K + Q +QQ+ ++A + Q I +L K S +++L ++L Q KR
Sbjct: 67 KQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKR 126
Query: 388 ALQEQCEITKREI-ELKER---TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
+ + RE+ ++++ E LQ ++ +E++ + L+ K TE
Sbjct: 127 TAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEA 186
Query: 444 LWAELQATKETLR--VTE---------DEVTTCKRE-----KESENKIGIQQKLAAELLN 487
L +++ ++ R +TE ++T+ ++E K EN +GI + E L
Sbjct: 187 LKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALA 246
Query: 488 KEEI----IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ-ESPNGISY 542
+E +G+++ Q ++ L+E+ IQ + +H++T+ + + ++
Sbjct: 247 AKEAADAELGQLRAQGGSSDSSLALHER--IQALEAELQAVSHSKTLLEKELQEVIALTS 304
Query: 543 QDLQ---QEIMDLKMKLLD---VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREE 596
Q+L+ +++++L+ +L + + + L E K ELE + G + E
Sbjct: 305 QELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALRE 364
Query: 597 LINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
++L+ ++ +L L ++ ++ +E ++Q+ +Q L A+LE ++++++
Sbjct: 365 HNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQM---KHLVQALQASLEKEKEKVNS 421
Query: 657 LEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAA 691
L++ V A +++ ++ EL A
Sbjct: 422 LKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQA 456
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 71.7 bits (168), Expect = 8e-12
Identities = 101/483 (20%), Positives = 210/483 (43%), Gaps = 25/483 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 963 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 1020
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + L + L +
Sbjct: 1021 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 1080
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ ++ L + + Q L L++ + LQ + E + E+E + +++ R+ +
Sbjct: 1081 KKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 418 -EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESENK 474
EL+ LE++ + E AE Q + L + E T K+ +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ +L ++ N + + K++ + E + ++ N +++I+ + +L+ RT+
Sbjct: 1200 VA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKMCRTLE 1253
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ Q + + ++ Q+ + DL + + N ELS L +K+ + Q +RG+
Sbjct: 1254 D-QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL---TRGKLTYT 1309
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATLENK 650
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + + ++
Sbjct: 1310 QQLEDLKRQLE-EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSE 1367
Query: 651 QQQ 653
Q
Sbjct: 1368 VAQ 1370
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 47/465 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
V + L +E ++ + +++ +++I + ++ E K + +++E R+ + +
Sbjct: 1213 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE--KMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTV---KMLEDQSRQKEVQLEARARKL 332
SQ + + ++ +QL E EA I+ LT G + + LED RQ E +++A+ L
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-NAL 1329
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
+L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 1330 AHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQRT 1383
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATK 452
E+ + + +L +R LQ++ A+E + AK LEK+K L E E DL +++ +
Sbjct: 1384 EELEEAKKKLAQR----LQEAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERSN 1436
Query: 453 ETLRVTE------DEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ D++ ++K ES++++ QK A L + + ++ E ++
Sbjct: 1437 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1496
Query: 505 NIKLNEQKVIQYE--QYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKL---- 556
K E K +Q E L + +TI ++ + + +LQ + + + L
Sbjct: 1497 TFK-RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 557 -------LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ E+ LA+KD+E+EQ +N RV+ + ++ E
Sbjct: 1556 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN---HLRVVDSLQTSLDAETRSRNEAL 1612
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R ++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 1613 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1657
Score = 65.7 bits (153), Expect = 5e-10
Identities = 82/438 (18%), Positives = 199/438 (45%), Gaps = 34/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E +KE L +E++ ++ ++ + ++ +
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTR-------LKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 947
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1007
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1008 DDLQAEEDKVNTLTKAK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL-IKNIKLNEQKVI--QYEQYVRDLQAHNRTIA 531
+ Q+ + +K+++ +++ + EL N ++ +++ + Q ++ +++LQA +
Sbjct: 1061 L-TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 1119
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRG 586
E+ + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 1120 EELEAER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRRD 1177
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 1178 LEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 647 LENKQQQIHRLEKIVLAL 664
+E + LEK+ L
Sbjct: 1235 MEQIIKAKANLEKMCRTL 1252
Score = 59.7 bits (138), Expect = 3e-08
Identities = 90/456 (19%), Positives = 190/456 (41%), Gaps = 38/456 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLT 277
+AL ++ K ++++ R ++E EL +E +E++R +L E ++E
Sbjct: 1098 QALGSQLQKKLKELQARIEELEE--ELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 1155
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
T Q+ + R A+ K R+ E + T L + +L + L+ +
Sbjct: 1156 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 1215
Query: 338 TGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
E S+ + D + + ++++ K +EK+ + + + ++T+R++ +
Sbjct: 1216 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND--- 1272
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQ 449
+T + +L +TE + ++E +A I +L + K DL + E ++ A+
Sbjct: 1273 LTSQRAKL----QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-N 1327
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
A L+ + + + E E + + + N E + + +T + + +L
Sbjct: 1328 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1387
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
E K ++ +A A C + LQ EI DL ++DV R+ +
Sbjct: 1388 EAKKKLAQRLQEAEEAVEAVNAKCSSLEK--TKHRLQNEIEDL---MVDV-ERSNAAAAA 1441
Query: 570 LAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L KK + ++ + K Q+ + ++E ++ TE + A ++ LEH +
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFKLKNAYEESLEH-LE 1496
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
NK + +EI +L L + + IH LEK+
Sbjct: 1497 TFKRENKNLQ---EEISDLTEQLGSSGKTIHELEKV 1529
Score = 58.0 bits (134), Expect = 1e-07
Identities = 88/500 (17%), Positives = 214/500 (42%), Gaps = 30/500 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1500
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + I E+ ++R + E K ALEE L+ E L
Sbjct: 1501 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1561 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK-K 1616
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1617 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1675
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++ A
Sbjct: 1676 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMDA 1732
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEE----IIGKMQIQTRELIKN 505
L+ E+ V C+ +E K + AE L KE+ + +M+ + IK+
Sbjct: 1733 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1792
Query: 506 I--KLNEQKVIQY---EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
+ +L+E + I ++ ++ L+A R + N E+ + + + + + + ++ ++
Sbjct: 1793 LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESV-KGMRKSERRIKELT 1851
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
++ EE + L + +++ + R + EE N +K + EL + E
Sbjct: 1852 YQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL----DEAE 1907
Query: 621 HRMRIVDEVNKQIAAKADEI 640
R I + ++ AK+ +I
Sbjct: 1908 ERADIAESQVNKLRAKSRDI 1927
Score = 56.0 bits (129), Expect = 4e-07
Identities = 121/557 (21%), Positives = 234/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL + + EH S+ E
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEHRSKAE----E 1265
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
++ +L +Q +LS R E+ LI+ L R Q +E ++E
Sbjct: 1266 TQRSVNDLTSQRAKLQTENGELS-RQLDEKEALIS---QLTRGKLTYTQQLEDLKRQLEE 1321
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E+++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 1322 --EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L+EAE ++ ++ LE + + ++E L ++
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1435
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1436 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1495
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + I ELEK + L E+ ++L + L+ + +L
Sbjct: 1496 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ--LEAEK-MELQSALEEAEASLE 1552
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEE-------IIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + E+ ++ +Q + +N
Sbjct: 1553 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 1611
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1612 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1666
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1726
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 1727 KKKMDADLSQLQTEVEE 1743
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1636 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1695 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 1754
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1755 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1811
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1812 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1871
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1923
>D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein.
Length = 1530
Score = 71.7 bits (168), Expect = 8e-12
Identities = 92/454 (20%), Positives = 205/454 (45%), Gaps = 23/454 (5%)
Query: 210 ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESE-NTKALEEMRHELDEERTA 268
E+RT A L REVA++RQ + + ++ R E E + ++L+ + ++ A
Sbjct: 893 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEA 952
Query: 269 KLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
A+K+++ E ++ R + + +++R + +TS K ++ + + E +
Sbjct: 953 NEALKKQI---EELQQEARKAITEQKQKMRRLGSDLTSAQ---KEMKTKHKAYENAVGIL 1006
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
+R+L+E+L E ++L Q R Q + + + ++ +Q + ++
Sbjct: 1007 SRRLQEALAAKEAADAELGQLR--AQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE 1064
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
LQE +T +E+E EL+D + KI LE+S L E E L
Sbjct: 1065 LQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGL 1124
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
+ LR + T ++E++ + + ++ A L KEE +M+ + L +++
Sbjct: 1125 GQSNAALREHNSILETALAKREAD-LVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEK 1183
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-S 567
++KV ++ V A + N ++ E+ ++K +L H ++L +
Sbjct: 1184 EKEKVNSLKEQV--------AAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQA 1235
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
E + +E + + ++ QA + + R +L +L+ + EQ + Q++E+ VD
Sbjct: 1236 EADDLQIREGKHSQEIAQFQAELAEARAQL-QLLQKQLDEQLSKQPVGNQEMENLKWEVD 1294
Query: 628 EVNKQIAAKADEIQELFATLENKQQQIHRLEKIV 661
+ ++I + Q+L T + ++++ L++++
Sbjct: 1295 QKEREIQSLK---QQLDLTEQQGRKELEGLQQLL 1325
Score = 66.5 bits (155), Expect = 3e-10
Identities = 91/432 (21%), Positives = 196/432 (45%), Gaps = 36/432 (8%)
Query: 161 QDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA 220
Q + I E + G +L A +E+KT+ + N V LS+R + +A EA
Sbjct: 964 QQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRL----QEALAAKEA 1019
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTE 280
E+ +LR + + + +++ +A+ + L++E ++E + T
Sbjct: 1020 ADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE------LQEVIALTS 1073
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+L ++R +V +++ +L+E+ +K LE+ +++ ++LE KL TG
Sbjct: 1074 QELEESREKVLELEDELQESR----GFRKKIKRLEESNKKLALELEHEKGKL-----TGL 1124
Query: 341 VTTSQLIQQRDS-LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEIT 396
++ +++ +S L+ + + + + +L +Q ++ +Q+ EE+ +Q K +ALQ E
Sbjct: 1125 GQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKE 1184
Query: 397 KREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
K ++ LKE+ ++ + +A +EL + K + + L +LQA + L
Sbjct: 1185 KEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKE----LQAKEHLVQKLQAEADDL 1240
Query: 456 RVTE----DEVTTCKRE-KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
++ E E+ + E E+ ++ + QK E L+K+ +G +++ + + K E
Sbjct: 1241 QIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQP-VGNQEMENLKWEVDQKERE 1299
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+ ++ + + + Q Q N S ++ QE DL M D ++SE+
Sbjct: 1300 IQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQE--DLSMTQKDKFMLQAKVSELK 1357
Query: 571 AKKDQELEQQDK 582
L+Q +
Sbjct: 1358 NNMKTLLQQNQQ 1369
Score = 62.9 bits (146), Expect = 4e-09
Identities = 112/561 (19%), Positives = 242/561 (43%), Gaps = 43/561 (7%)
Query: 126 DAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGA 185
++ A+ T E L++L E M +E ++ +L +Q + L+ +
Sbjct: 397 ESSAAETQEEMLQVLKEKMRLEGQLE--ALSLEASQALKEKAELQAQLAALSTKLQAQVE 454
Query: 186 LRELKTQAEDAVNTVTDLSKRACHE-RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
Q +D++++ D K++C + R + + L + A L V ++ +
Sbjct: 455 CSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQR 514
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
L ++ E+ + R L ++ T +++++T +SQL+Q + + +L+ ++A I
Sbjct: 515 LMAKVEDMQ-----RSMLSKDNTVH-DLRQQMTALQSQLQQVQLERTTLTSKLKASQAEI 568
Query: 305 TSLTGTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECK 361
+SL + + Q +++ V+L+ ++ T L + SL ++ E +
Sbjct: 569 SSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGILEHLKLENVSLSQQLTETQ 628
Query: 362 QQIEKLTVQHKSAIQQLEED----------LKQTKRALQEQCEITKREIELKERTETELQ 411
+ K + + +Q +E D +++ K ++E + E E + +
Sbjct: 629 HRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMA 688
Query: 412 DSRNAIEEL--QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE- 468
DS ++E+ Q K+ L++ + L E +DL +L T+E L+ E + +
Sbjct: 689 DSAASLEQQLEQVKLTLLQRDQQLEALQQE-HLDLMKQLTLTQEALQSREQSLDALQTHY 747
Query: 469 KESENKIGIQQKLAAE------LLNKEEIIGKMQIQT-----RELIKNIKLNEQKVIQYE 517
E + ++G Q AA LL E+II + +Q EL + + E+ +
Sbjct: 748 DELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETS 807
Query: 518 QYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL 577
+ + L+ I + Q L++++ +K + L E KDQ +
Sbjct: 808 ETLEKLR-EELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLI 866
Query: 578 -EQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDL-EHRMRIVD-EVNKQIA 634
E + R + + ++R+EL+ V K T ++ EL+ L +++ + R + D E + Q A
Sbjct: 867 SELKATRKRLDSELKELRQELMQVHGEKRTAEA-ELSRLHREVAQVRQHMADLEGHLQSA 925
Query: 635 AK-ADEIQELFATLENKQQQI 654
K DE++ +L+ ++Q+
Sbjct: 926 QKERDEMETHLQSLQFDKEQM 946
Score = 52.4 bits (120), Expect = 5e-06
Identities = 104/523 (19%), Positives = 224/523 (42%), Gaps = 58/523 (11%)
Query: 158 TVNQDQTDGDILEHLS-RYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
T+ Q + D+L+ + + DQG E+ G +R + D++ + L A + ++
Sbjct: 354 TLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRR----DSICSSVSLESSAAETQEEMLQ 409
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSE----SENTKALEEMRHELDEERTAKLAI 272
V + +R +L + + E EL+++ S +A E H + + + +
Sbjct: 410 VLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDS---L 466
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
++ T + + + L AS+ S +++ E+Q ++ L A+ +
Sbjct: 467 SSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQR----LMAKVEDM 522
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE-EDLKQTKRALQE 391
+ S+ + + T L QQ +LQ+++ + Q+E+ T+ K Q E L+ ++ Q+
Sbjct: 523 QRSMLSKDNTVHDLRQQMTALQSQLQQV--QLERTTLTSKLKASQAEISSLQSVRQWYQQ 580
Query: 392 QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
Q + + E + R + E+ + + QA I+E K
Sbjct: 581 QLALAQ---EARVRLQGEMAHIQVG-QMTQAGILEHLKL--------------------- 615
Query: 452 KETLRVTEDEVTTCKREKESENKIGIQ-QKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
E + +++ T R + + +I Q Q + A++L++E MQIQ + + L +
Sbjct: 616 -ENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAF--MQIQEAKTMVEEDL-Q 671
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ--QEIMDLKMKLLDVVHRNEELSE 568
+++ ++E LQ + A+ ++ + LQ Q++ L+ + LD++ + E
Sbjct: 672 RRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQE 731
Query: 569 ILAKKDQELEQ-QDKNSRGQARVIKI------REELINVLKNKETEQSRELAALQQDLEH 621
L ++Q L+ Q QAR+ ++ RE+ I +L+N++ L A + E
Sbjct: 732 ALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEE 791
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
R + + ++ +++L L K Q+ L++ AL
Sbjct: 792 LDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAAL 834
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 71.7 bits (168), Expect = 8e-12
Identities = 101/483 (20%), Positives = 210/483 (43%), Gaps = 25/483 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 963 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 1020
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + L + L +
Sbjct: 1021 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 1080
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ ++ L + + Q L L++ + LQ + E + E+E + +++ R+ +
Sbjct: 1081 KKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 418 -EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESENK 474
EL+ LE++ + E AE Q + L + E T K+ +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ +L ++ N + + K++ + E + ++ N +++I+ + +L+ RT+
Sbjct: 1200 VA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKMCRTLE 1253
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ Q + + ++ Q+ + DL + + N ELS L +K+ + Q +RG+
Sbjct: 1254 D-QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL---TRGKLTYT 1309
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATLENK 650
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + + ++
Sbjct: 1310 QQLEDLKRQLE-EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSE 1367
Query: 651 QQQ 653
Q
Sbjct: 1368 VAQ 1370
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 47/465 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
V + L +E ++ + +++ +++I + ++ E K + +++E R+ + +
Sbjct: 1213 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE--KMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTV---KMLEDQSRQKEVQLEARARKL 332
SQ + + ++ +QL E EA I+ LT G + + LED RQ E +++A+ L
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-NAL 1329
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
+L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 1330 AHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQRT 1383
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATK 452
E+ + + +L +R LQ++ A+E + AK LEK+K L E E DL +++ +
Sbjct: 1384 EELEEAKKKLAQR----LQEAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERSN 1436
Query: 453 ETLRVTE------DEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ D++ ++K ES++++ QK A L + + ++ E ++
Sbjct: 1437 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1496
Query: 505 NIKLNEQKVIQYE--QYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKL---- 556
K E K +Q E L + +TI ++ + + +LQ + + + L
Sbjct: 1497 TFK-RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 557 -------LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ E+ LA+KD+E+EQ +N RV+ + ++ E
Sbjct: 1556 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN---HLRVVDSLQTSLDAETRSRNEAL 1612
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R ++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 1613 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1657
Score = 65.7 bits (153), Expect = 5e-10
Identities = 82/438 (18%), Positives = 199/438 (45%), Gaps = 34/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E +KE L +E++ ++ ++ + ++ +
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTR-------LKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 947
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1007
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1008 DDLQAEEDKVNTLTKAK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL-IKNIKLNEQKVI--QYEQYVRDLQAHNRTIA 531
+ Q+ + +K+++ +++ + EL N ++ +++ + Q ++ +++LQA +
Sbjct: 1061 L-TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 1119
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRG 586
E+ + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 1120 EELEAER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRRD 1177
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 1178 LEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 647 LENKQQQIHRLEKIVLAL 664
+E + LEK+ L
Sbjct: 1235 MEQIIKAKANLEKMCRTL 1252
Score = 59.7 bits (138), Expect = 3e-08
Identities = 90/456 (19%), Positives = 190/456 (41%), Gaps = 38/456 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLT 277
+AL ++ K ++++ R ++E EL +E +E++R +L E ++E
Sbjct: 1098 QALGSQLQKKLKELQARIEELEE--ELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 1155
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
T Q+ + R A+ K R+ E + T L + +L + L+ +
Sbjct: 1156 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 1215
Query: 338 TGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
E S+ + D + + ++++ K +EK+ + + + ++T+R++ +
Sbjct: 1216 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND--- 1272
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQ 449
+T + +L +TE + ++E +A I +L + K DL + E ++ A+
Sbjct: 1273 LTSQRAKL----QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-N 1327
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
A L+ + + + E E + + + N E + + +T + + +L
Sbjct: 1328 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1387
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
E K ++ +A A C + LQ EI DL ++DV R+ +
Sbjct: 1388 EAKKKLAQRLQEAEEAVEAVNAKCSSLEK--TKHRLQNEIEDL---MVDV-ERSNAAAAA 1441
Query: 570 LAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L KK + ++ + K Q+ + ++E ++ TE + A ++ LEH +
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFKLKNAYEESLEH-LE 1496
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
NK + +EI +L L + + IH LEK+
Sbjct: 1497 TFKRENKNLQ---EEISDLTEQLGSSGKTIHELEKV 1529
Score = 58.0 bits (134), Expect = 1e-07
Identities = 88/500 (17%), Positives = 214/500 (42%), Gaps = 30/500 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1500
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + I E+ ++R + E K ALEE L+ E L
Sbjct: 1501 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1561 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK-K 1616
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1617 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1675
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++ A
Sbjct: 1676 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMDA 1732
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEE----IIGKMQIQTRELIKN 505
L+ E+ V C+ +E K + AE L KE+ + +M+ + IK+
Sbjct: 1733 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1792
Query: 506 I--KLNEQKVIQY---EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
+ +L+E + I ++ ++ L+A R + N E+ + + + + + + ++ ++
Sbjct: 1793 LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESV-KGMRKSERRIKELT 1851
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
++ EE + L + +++ + R + EE N +K + EL + E
Sbjct: 1852 YQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL----DEAE 1907
Query: 621 HRMRIVDEVNKQIAAKADEI 640
R I + ++ AK+ +I
Sbjct: 1908 ERADIAESQVNKLRAKSRDI 1927
Score = 56.0 bits (129), Expect = 4e-07
Identities = 121/557 (21%), Positives = 234/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL + + EH S+ E
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEHRSKAE----E 1265
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
++ +L +Q +LS R E+ LI+ L R Q +E ++E
Sbjct: 1266 TQRSVNDLTSQRAKLQTENGELS-RQLDEKEALIS---QLTRGKLTYTQQLEDLKRQLEE 1321
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E+++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 1322 --EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L+EAE ++ ++ LE + + ++E L ++
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1435
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1436 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1495
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + I ELEK + L E+ ++L + L+ + +L
Sbjct: 1496 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ--LEAEK-MELQSALEEAEASLE 1552
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEE-------IIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + E+ ++ +Q + +N
Sbjct: 1553 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 1611
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1612 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1666
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1726
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 1727 KKKMDADLSQLQTEVEE 1743
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1636 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1695 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 1754
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1755 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1811
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1812 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1871
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1923
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 71.7 bits (168), Expect = 8e-12
Identities = 101/483 (20%), Positives = 210/483 (43%), Gaps = 25/483 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 963 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 1020
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + L + L +
Sbjct: 1021 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 1080
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ ++ L + + Q L L++ + LQ + E + E+E + +++ R+ +
Sbjct: 1081 KKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 418 -EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESENK 474
EL+ LE++ + E AE Q + L + E T K+ +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ +L ++ N + + K++ + E + ++ N +++I+ + +L+ RT+
Sbjct: 1200 VA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKMCRTLE 1253
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ Q + + ++ Q+ + DL + + N ELS L +K+ + Q +RG+
Sbjct: 1254 D-QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL---TRGKLTYT 1309
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATLENK 650
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + + ++
Sbjct: 1310 QQLEDLKRQLE-EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSE 1367
Query: 651 QQQ 653
Q
Sbjct: 1368 VAQ 1370
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 47/465 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
V + L +E ++ + +++ +++I + ++ E K + +++E R+ + +
Sbjct: 1213 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE--KMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTV---KMLEDQSRQKEVQLEARARKL 332
SQ + + ++ +QL E EA I+ LT G + + LED RQ E +++A+ L
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-NAL 1329
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
+L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 1330 AHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQRT 1383
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATK 452
E+ + + +L +R LQ++ A+E + AK LEK+K L E E DL +++ +
Sbjct: 1384 EELEEAKKKLAQR----LQEAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERSN 1436
Query: 453 ETLRVTE------DEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ D++ ++K ES++++ QK A L + + ++ E ++
Sbjct: 1437 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1496
Query: 505 NIKLNEQKVIQYE--QYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKL---- 556
K E K +Q E L + +TI ++ + + +LQ + + + L
Sbjct: 1497 TFK-RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 557 -------LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ E+ LA+KD+E+EQ +N RV+ + ++ E
Sbjct: 1556 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN---HLRVVDSLQTSLDAETRSRNEAL 1612
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R ++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 1613 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1657
Score = 65.7 bits (153), Expect = 5e-10
Identities = 82/438 (18%), Positives = 199/438 (45%), Gaps = 34/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E +KE L +E++ ++ ++ + ++ +
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTR-------LKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 947
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1007
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1008 DDLQAEEDKVNTLTKAK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL-IKNIKLNEQKVI--QYEQYVRDLQAHNRTIA 531
+ Q+ + +K+++ +++ + EL N ++ +++ + Q ++ +++LQA +
Sbjct: 1061 L-TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 1119
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRG 586
E+ + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 1120 EELEAER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRRD 1177
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 1178 LEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 647 LENKQQQIHRLEKIVLAL 664
+E + LEK+ L
Sbjct: 1235 MEQIIKAKANLEKMCRTL 1252
Score = 59.7 bits (138), Expect = 3e-08
Identities = 90/456 (19%), Positives = 190/456 (41%), Gaps = 38/456 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLT 277
+AL ++ K ++++ R ++E EL +E +E++R +L E ++E
Sbjct: 1098 QALGSQLQKKLKELQARIEELEE--ELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 1155
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
T Q+ + R A+ K R+ E + T L + +L + L+ +
Sbjct: 1156 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 1215
Query: 338 TGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
E S+ + D + + ++++ K +EK+ + + + ++T+R++ +
Sbjct: 1216 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND--- 1272
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQ 449
+T + +L +TE + ++E +A I +L + K DL + E ++ A+
Sbjct: 1273 LTSQRAKL----QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-N 1327
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
A L+ + + + E E + + + N E + + +T + + +L
Sbjct: 1328 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1387
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
E K ++ +A A C + LQ EI DL ++DV R+ +
Sbjct: 1388 EAKKKLAQRLQEAEEAVEAVNAKCSSLEK--TKHRLQNEIEDL---MVDV-ERSNAAAAA 1441
Query: 570 LAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L KK + ++ + K Q+ + ++E ++ TE + A ++ LEH +
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFKLKNAYEESLEH-LE 1496
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
NK + +EI +L L + + IH LEK+
Sbjct: 1497 TFKRENKNLQ---EEISDLTEQLGSSGKTIHELEKV 1529
Score = 58.0 bits (134), Expect = 1e-07
Identities = 88/500 (17%), Positives = 214/500 (42%), Gaps = 30/500 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1500
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + I E+ ++R + E K ALEE L+ E L
Sbjct: 1501 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1561 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK-K 1616
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1617 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1675
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++ A
Sbjct: 1676 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMDA 1732
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEE----IIGKMQIQTRELIKN 505
L+ E+ V C+ +E K + AE L KE+ + +M+ + IK+
Sbjct: 1733 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1792
Query: 506 I--KLNEQKVIQY---EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
+ +L+E + I ++ ++ L+A R + N E+ + + + + + + ++ ++
Sbjct: 1793 LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESV-KGMRKSERRIKELT 1851
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
++ EE + L + +++ + R + EE N +K + EL + E
Sbjct: 1852 YQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL----DEAE 1907
Query: 621 HRMRIVDEVNKQIAAKADEI 640
R I + ++ AK+ +I
Sbjct: 1908 ERADIAESQVNKLRAKSRDI 1927
Score = 56.0 bits (129), Expect = 4e-07
Identities = 121/557 (21%), Positives = 234/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL + + EH S+ E
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEHRSKAE----E 1265
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
++ +L +Q +LS R E+ LI+ L R Q +E ++E
Sbjct: 1266 TQRSVNDLTSQRAKLQTENGELS-RQLDEKEALIS---QLTRGKLTYTQQLEDLKRQLEE 1321
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E+++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 1322 --EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L+EAE ++ ++ LE + + ++E L ++
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1435
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1436 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1495
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + I ELEK + L E+ ++L + L+ + +L
Sbjct: 1496 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ--LEAEK-MELQSALEEAEASLE 1552
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEE-------IIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + E+ ++ +Q + +N
Sbjct: 1553 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 1611
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1612 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1666
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1726
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 1727 KKKMDADLSQLQTEVEE 1743
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1636 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1695 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 1754
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1755 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1811
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1812 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1871
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1923
>BC048203-1|AAH48203.1| 663|Homo sapiens Unknown (protein for
IMAGE:4139784) protein.
Length = 663
Score = 71.7 bits (168), Expect = 8e-12
Identities = 92/454 (20%), Positives = 205/454 (45%), Gaps = 23/454 (5%)
Query: 210 ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESE-NTKALEEMRHELDEERTA 268
E+RT A L REVA++RQ + + ++ R E E + ++L+ + ++ A
Sbjct: 105 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEA 164
Query: 269 KLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
A+K+++ E ++ R + + +++R + +TS K ++ + + E +
Sbjct: 165 NEALKKQI---EELQQEARKAITEQKQKMRRLGSDLTSAQ---KEMKTKHKAYENAVGIL 218
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
+R+L+E+L E ++L Q R Q + + + ++ +Q + ++
Sbjct: 219 SRRLQEALAAKEAADAELGQLR--AQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE 276
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
LQE +T +E+E EL+D + KI LE+S L E E L
Sbjct: 277 LQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGL 336
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
+ LR + T ++E++ + + ++ A L KEE +M+ + L +++
Sbjct: 337 GQSNAALREHNSILETALAKREAD-LVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEK 395
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-S 567
++KV ++ V A + N ++ E+ ++K +L H ++L +
Sbjct: 396 EKEKVNSLKEQV--------AAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQA 447
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
E + +E + + ++ QA + + R +L +L+ + EQ + Q++E+ VD
Sbjct: 448 EADDLQIREGKHSQEIAQFQAELAEARAQL-QLLQKQLDEQLSKQPVGNQEMENLKWEVD 506
Query: 628 EVNKQIAAKADEIQELFATLENKQQQIHRLEKIV 661
+ ++I + Q+L T + ++++ L++++
Sbjct: 507 QKEREIQSLK---QQLDLTEQQGRKELEGLQQLL 537
Score = 66.5 bits (155), Expect = 3e-10
Identities = 91/432 (21%), Positives = 196/432 (45%), Gaps = 36/432 (8%)
Query: 161 QDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA 220
Q + I E + G +L A +E+KT+ + N V LS+R + +A EA
Sbjct: 176 QQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRL----QEALAAKEA 231
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTE 280
E+ +LR + + + +++ +A+ + L++E ++E + T
Sbjct: 232 ADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE------LQEVIALTS 285
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+L ++R +V +++ +L+E+ +K LE+ +++ ++LE KL TG
Sbjct: 286 QELEESREKVLELEDELQESR----GFRKKIKRLEESNKKLALELEHEKGKL-----TGL 336
Query: 341 VTTSQLIQQRDS-LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEIT 396
++ +++ +S L+ + + + + +L +Q ++ +Q+ EE+ +Q K +ALQ E
Sbjct: 337 GQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKE 396
Query: 397 KREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
K ++ LKE+ ++ + +A +EL + K + + L +LQA + L
Sbjct: 397 KEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKE----LQAKEHLVQKLQAEADDL 452
Query: 456 RVTE----DEVTTCKRE-KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
++ E E+ + E E+ ++ + QK E L+K+ +G +++ + + K E
Sbjct: 453 QIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQP-VGNQEMENLKWEVDQKERE 511
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+ ++ + + + Q Q N S ++ QE DL M D ++SE+
Sbjct: 512 IQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQE--DLSMTQKDKFMLQAKVSELK 569
Query: 571 AKKDQELEQQDK 582
L+Q +
Sbjct: 570 NNMKTLLQQNQQ 581
Score = 47.2 bits (107), Expect = 2e-04
Identities = 83/440 (18%), Positives = 194/440 (44%), Gaps = 45/440 (10%)
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
++D+ R E + T++ L ++ K Q+E ++ K + Q +QQ+
Sbjct: 3 ELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKV 62
Query: 352 SLQA---EVLECKQQIEKLTVQHK---SAIQQLEEDLKQT---KRALQEQCEITKREI-E 401
++A + Q I +L K S +++L ++L Q KR + + RE+ +
Sbjct: 63 MVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQ 122
Query: 402 LKER---TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR-- 456
+++ E LQ ++ +E++ + L+ K TE L +++ ++ R
Sbjct: 123 VRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKA 182
Query: 457 VTE---------DEVTTCKRE-----KESENKIGIQQKLAAELLNKEEI----IGKMQIQ 498
+TE ++T+ ++E K EN +GI + E L +E +G+++ Q
Sbjct: 183 ITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQ 242
Query: 499 TRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQ-ESPNGISYQDLQ---QEIMDLKM 554
++ L+E+ IQ + +H++T+ + + ++ Q+L+ +++++L+
Sbjct: 243 GGSSDSSLALHER--IQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELED 300
Query: 555 KLLD---VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRE 611
+L + + + L E K ELE + G + E ++L+ ++ +
Sbjct: 301 ELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREAD 360
Query: 612 LAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXX 671
L L ++ ++ +E ++Q+ +Q L A+LE ++++++ L++ V A
Sbjct: 361 LVQLNLQVQAVLQRKEEEDRQM---KHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHN 417
Query: 672 XXXXXXXXXKIAALEHELAA 691
+++ ++ EL A
Sbjct: 418 RRHFKAASLELSEVKKELQA 437
>BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein.
Length = 1006
Score = 71.7 bits (168), Expect = 8e-12
Identities = 94/453 (20%), Positives = 200/453 (44%), Gaps = 36/453 (7%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
AL + +L Q VE +++ ++LR ++E K E +L +E A A ++K
Sbjct: 91 ALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAA-QDK---- 145
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+Q ++ K D +L + + ++L Q ++K +L+ARA +L E L+
Sbjct: 146 ----QQLEEKLKKKDSELSQLSLRVED----EQLLGAQMQKKIKELQARAEELEEELEAE 197
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
+++ +QR E+ E +++E+ + + ++ E +L + +R L+E
Sbjct: 198 RAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRH 257
Query: 397 KREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ + R + E + ++ LQ +LEK K E+D A T
Sbjct: 258 EATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSE----LRMEVDDLAANVETLTRA 313
Query: 456 RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQ 515
+ + +++ ++ SE KI +++ L +L + G++Q ++ EL + ++ E + Q
Sbjct: 314 KASAEKLCRTYEDQLSEAKIKVEE-LQRQLADASTQRGRLQTESGELSRLLEEKECLISQ 372
Query: 516 YEQ----YVRDLQAHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEI 569
+ + L+ R + ++ + +++ Q L+ + L+ + + EL +
Sbjct: 373 LSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRL 432
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELIN-----VLKNKETEQSRELA-ALQQDLEHRM 623
L+K + E+ Q S+ +A I+ EEL L+ +E E+ E A A LE
Sbjct: 433 LSKANAEVAQW--RSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAK 490
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ ++ + + + A L+ KQ+ + R
Sbjct: 491 LRLQTESEDVTLELERATSAAAALDKKQRHLER 523
Score = 57.2 bits (132), Expect = 2e-07
Identities = 102/448 (22%), Positives = 197/448 (43%), Gaps = 47/448 (10%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
E AKLR E+ +V ++ R + + K + L+E R + ++ +L + +
Sbjct: 487 EKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRES 546
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R + ++ EA ++ +L K L+++ Q+ + ++E E T
Sbjct: 547 RGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQEL----EKTK 602
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
L ++ +QA + E + +E + K+ QLE L Q K E+ ++ E
Sbjct: 603 KALEGEKSEIQAALEEAEGALE--LEETKTLRIQLE--LSQVK------AEVDRKLAEKD 652
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI--DL-WAELQATKETLRVTED 460
E ++ + A+E LQA ++ E N L ++++ DL ELQ T + TE
Sbjct: 653 EECANLRRNHQRAVESLQAS-LDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEA 711
Query: 461 EVTTCKRE---KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
+ T + KE + +Q+LAAEL + + ++ R + +L E + E
Sbjct: 712 QAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQ-----ALERRASLLAAELEELRA-ALE 765
Query: 518 QYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL-LDVVHRNEELSEILAKKDQE 576
Q R + + + E N + Q+ +++ K KL D+ + E+ E A++ +E
Sbjct: 766 QGERSRRLAEQELLEATERLNLLHSQN--TGLLNQKKKLEADLAQLSGEVEE-AAQERRE 822
Query: 577 LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAK 636
E++ K + A + + EEL KE + S L +++ LE +R ++ A+
Sbjct: 823 AEEKAKKAITDAAM--MAEEL-----KKEQDTSAHLERMKKTLEQTVR-------ELQAR 868
Query: 637 ADEIQELFATLENKQQQIHRLEKIVLAL 664
+E ++ A L ++Q+ +LE V L
Sbjct: 869 LEEAEQ--AALRGGKKQVQKLEAKVREL 894
Score = 47.6 bits (108), Expect = 1e-04
Identities = 91/459 (19%), Positives = 193/459 (42%), Gaps = 36/459 (7%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+G + +++ +L+ E ++ R R+ E +A E EL EE + +L +E
Sbjct: 172 LGAQMQKKIKELQARAEELEEELEAERAARARVEKQRA--EAAREL-EELSERL--EEAG 226
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
+ Q R R A++ + RE E + TV L R+K+ + A +L E +
Sbjct: 227 GASAGQREGCRKREAELGRLRRELEEAALRHEATVAAL----RRKQAE---GAAELGEQV 279
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA---IQQLEEDLKQTKRALQE-Q 392
+ + +L +++ L+ EV + +E LT SA + E+ L + K ++E Q
Sbjct: 280 DSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQ 339
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE---REIDLWAELQ 449
++ + + R +TE + +EE + I +L + K E R+++ ++ +
Sbjct: 340 RQLADASTQ-RGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAK 398
Query: 450 -ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
A ++ + + + E E + + + N E + + + + + +L
Sbjct: 399 SALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEEL 458
Query: 509 NEQK---VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
E K ++ ++ ++A N ++ +++ LQ E D+ ++L R
Sbjct: 459 EEAKKKLALRLQEAEEGVEAANAKCSSLEKAK-----LRLQTESEDVTLEL----ERATS 509
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
+ L KK + LE+ + R Q ++ RE + + + EL L+ E +
Sbjct: 510 AAAALDKKQRHLERALEERRRQEEEMQ-RE--LEAAQRESRGLGTELFRLRHGHEEALEA 566
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
++ + ++ +EI +L + + I LEK AL
Sbjct: 567 LETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKAL 605
Score = 43.6 bits (98), Expect = 0.002
Identities = 57/279 (20%), Positives = 115/279 (41%), Gaps = 17/279 (6%)
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
R +E A M+ +L EE+ + + Q + R + + +L E A++
Sbjct: 706 RQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALE 765
Query: 306 SLTGTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
+ ++ E + + ++ L ++ L K E +QL + + E E ++
Sbjct: 766 QGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEE 825
Query: 363 QIEKLTVQHKSAIQQL--EEDLKQTKRALQEQCEITKREIE--LKERTETELQDSRNAIE 418
+ +K ++L E+D +++ E T RE++ L+E + L+ + ++
Sbjct: 826 KAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQ 885
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+L+AK+ ELE +L E++ A K RV E + +E +
Sbjct: 886 KLEAKVRELE-----AELDAEQKKHAEALKGVRKHERRVKE----LAYQAEEDRKNLARM 936
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
Q L +L +K + K Q + E N L + + Q+E
Sbjct: 937 QDLVDKLQSKVKSY-KRQFEEAEQQANTNLAKYRKAQHE 974
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 71.7 bits (168), Expect = 8e-12
Identities = 101/483 (20%), Positives = 210/483 (43%), Gaps = 25/483 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 147 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 206
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 207 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 264
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + L + L +
Sbjct: 265 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 324
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ ++ L + + Q L L++ + LQ + E + E+E + +++ R+ +
Sbjct: 325 KKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 383
Query: 418 -EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESENK 474
EL+ LE++ + E AE Q + L + E T K+ +
Sbjct: 384 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 443
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ +L ++ N + + K++ + E + ++ N +++I+ + +L+ RT+
Sbjct: 444 VA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKMCRTLE 497
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ Q + + ++ Q+ + DL + + N ELS L +K+ + Q +RG+
Sbjct: 498 D-QMNEHRSKAEETQRSVNDLTSQQAKLQTENGELSRQLDEKEALISQL---TRGKLTYT 553
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATLENK 650
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + + ++
Sbjct: 554 QQLEDLKRQLE-EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSE 611
Query: 651 QQQ 653
Q
Sbjct: 612 VAQ 614
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 47/465 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
V + L +E ++ + +++ +++I + ++ E K + +++E R+ + +
Sbjct: 457 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE--KMCRTLEDQMNEHRSKAEETQRSV 514
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTV---KMLEDQSRQKEVQLEARARKL 332
SQ + + ++ +QL E EA I+ LT G + + LED RQ E +++A+ L
Sbjct: 515 NDLTSQQAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-NAL 573
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
+L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 574 AHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQRT 627
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATK 452
E+ + + +L +R LQ++ A+E + AK LEK+K L E E DL +++ +
Sbjct: 628 EELEEAKKKLAQR----LQEAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERSN 680
Query: 453 ETLRVTE------DEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ D++ ++K ES++++ QK A L + + ++ E ++
Sbjct: 681 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 740
Query: 505 NIKLNEQKVIQYE--QYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKL---- 556
K E K +Q E L + +TI ++ + + +LQ + + + L
Sbjct: 741 TFK-RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 799
Query: 557 -------LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ E+ LA+KD+E+EQ +N RV+ + ++ E
Sbjct: 800 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN---HLRVVDSLQTSLDAETRSRNEAL 856
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R ++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 857 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 901
Score = 65.7 bits (153), Expect = 5e-10
Identities = 82/438 (18%), Positives = 199/438 (45%), Gaps = 34/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E +KE L +E++ ++ ++ + ++ +
Sbjct: 79 KIKPLLKSAEREKEMASMKEEFTR-------LKEALEKSEARRKELEEKMVSLLQEKNDL 131
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 132 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 191
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 192 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 251
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 252 DDLQAEEDKVNTLTKAK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 304
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL-IKNIKLNEQKVI--QYEQYVRDLQAHNRTIA 531
+ Q+ + +K+++ +++ + EL N ++ +++ + Q ++ +++LQA +
Sbjct: 305 L-TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 363
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRG 586
E+ + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 364 EELEAER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRRD 421
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 422 LEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 478
Query: 647 LENKQQQIHRLEKIVLAL 664
+E + LEK+ L
Sbjct: 479 MEQIIKAKANLEKMCRTL 496
Score = 60.5 bits (140), Expect = 2e-08
Identities = 90/456 (19%), Positives = 191/456 (41%), Gaps = 38/456 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLT 277
+AL ++ K ++++ R ++E EL +E +E++R +L E ++E
Sbjct: 342 QALGSQLQKKLKELQARIEELEE--ELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 399
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
T Q+ + R A+ K R+ E + T L + +L + L+ +
Sbjct: 400 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 459
Query: 338 TGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
E S+ + D + + ++++ K +EK+ + + + ++T+R++ +
Sbjct: 460 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND--- 516
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQ 449
+T ++ +L +TE + ++E +A I +L + K DL + E ++ A+
Sbjct: 517 LTSQQAKL----QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-N 571
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
A L+ + + + E E + + + N E + + +T + + +L
Sbjct: 572 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 631
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
E K ++ +A A C + LQ EI DL ++DV R+ +
Sbjct: 632 EAKKKLAQRLQEAEEAVEAVNAKCSSLEK--TKHRLQNEIEDL---MVDV-ERSNAAAAA 685
Query: 570 LAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L KK + ++ + K Q+ + ++E ++ TE + A ++ LEH +
Sbjct: 686 LDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFKLKNAYEESLEH-LE 740
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
NK + +EI +L L + + IH LEK+
Sbjct: 741 TFKRENKNLQ---EEISDLTEQLGSSGKTIHELEKV 773
Score = 58.0 bits (134), Expect = 1e-07
Identities = 88/500 (17%), Positives = 214/500 (42%), Gaps = 30/500 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 686 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 744
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + I E+ ++R + E K ALEE L+ E L
Sbjct: 745 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 804
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 805 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK-K 860
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 861 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 919
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++ A
Sbjct: 920 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMDA 976
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEE----IIGKMQIQTRELIKN 505
L+ E+ V C+ +E K + AE L KE+ + +M+ + IK+
Sbjct: 977 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1036
Query: 506 I--KLNEQKVIQY---EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
+ +L+E + I ++ ++ L+A R + N E+ + + + + + + ++ ++
Sbjct: 1037 LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESV-KGMRKSERRIKELT 1095
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
++ EE + L + +++ + R + EE N +K + EL + E
Sbjct: 1096 YQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL----DEAE 1151
Query: 621 HRMRIVDEVNKQIAAKADEI 640
R I + ++ AK+ +I
Sbjct: 1152 ERADIAESQVNKLRAKSRDI 1171
Score = 56.0 bits (129), Expect = 4e-07
Identities = 121/557 (21%), Positives = 234/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL + + EH S+ E
Sbjct: 455 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEHRSKAE----E 509
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
++ +L +Q +LS R E+ LI+ L R Q +E ++E
Sbjct: 510 TQRSVNDLTSQQAKLQTENGELS-RQLDEKEALIS---QLTRGKLTYTQQLEDLKRQLEE 565
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E+++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 566 --EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 623
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L+EAE ++ ++ LE + + ++E L ++
Sbjct: 624 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 679
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 680 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 739
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + I ELEK + L E+ ++L + L+ + +L
Sbjct: 740 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ--LEAEK-MELQSALEEAEASLE 796
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEE-------IIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + E+ ++ +Q + +N
Sbjct: 797 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 855
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 856 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 910
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 911 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 970
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 971 KKKMDADLSQLQTEVEE 987
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 880 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 938
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 939 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 998
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 999 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1055
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1056 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1115
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1116 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1167
>AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 71.7 bits (168), Expect = 8e-12
Identities = 94/453 (20%), Positives = 200/453 (44%), Gaps = 36/453 (7%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
AL + +L Q VE +++ ++LR ++E K E +L +E A A ++K
Sbjct: 1068 ALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAA-QDK---- 1122
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+Q ++ K D +L + + ++L Q ++K +L+ARA +L E L+
Sbjct: 1123 ----QQLEEKLKKKDSELSQLSLRVED----EQLLGAQMQKKIKELQARAEELEEELEAE 1174
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
+++ +QR E+ E +++E+ + + ++ E +L + +R L+E
Sbjct: 1175 RAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRH 1234
Query: 397 KREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ + R + E + ++ LQ +LEK K E+D A T
Sbjct: 1235 EATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSE----LRMEVDDLAANVETLTRA 1290
Query: 456 RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQ 515
+ + +++ ++ SE KI +++ L +L + G++Q ++ EL + ++ E + Q
Sbjct: 1291 KASAEKLCRTYEDQLSEAKIKVEE-LQRQLADASTQRGRLQTESGELSRLLEEKECLISQ 1349
Query: 516 YEQ----YVRDLQAHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEI 569
+ + L+ R + ++ + +++ Q L+ + L+ + + EL +
Sbjct: 1350 LSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRL 1409
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELIN-----VLKNKETEQSRELA-ALQQDLEHRM 623
L+K + E+ Q S+ +A I+ EEL L+ +E E+ E A A LE
Sbjct: 1410 LSKANAEVAQW--RSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAK 1467
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ ++ + + + A L+ KQ+ + R
Sbjct: 1468 LRLQTESEDVTLELERATSAAAALDKKQRHLER 1500
Score = 62.1 bits (144), Expect = 6e-09
Identities = 78/415 (18%), Positives = 191/415 (46%), Gaps = 39/415 (9%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTG-----TVKMLEDQSR-------- 319
+E+L ++LR R +A + + +E E + S+T +++ +Q
Sbjct: 895 EEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERC 954
Query: 320 ----QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI 375
+ +VQLE + ++L E L+ E + L +R L+ E E K+ I+ L + A
Sbjct: 955 HLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAE 1014
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA---KIIELEKSKP 432
++ + + K +E + + L + + + + A+ +LQA ++ L K+K
Sbjct: 1015 KEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAK- 1073
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEII 492
L E++++ +L+ + E + + KR+ E + K+ Q+ +A +K+++
Sbjct: 1074 ---LRLEQQVE---DLECSLEQEKKLRMDTERAKRKLEGDLKL-TQESVADAAQDKQQLE 1126
Query: 493 GKMQIQTRELIK-NIKLNEQKVI--QYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI 549
K++ + EL + ++++ +++++ Q ++ +++LQA + E+ + ++++
Sbjct: 1127 EKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARAR-VEKQR 1185
Query: 550 MDLKMKLLDVVHRNEELSEILAKKDQELEQQDK---NSRGQARVIKIREE-LINVLKNKE 605
+ +L ++ R EE A + + +++ R + +R E + L+ K+
Sbjct: 1186 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 1245
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
E + EL + ++ R+ ++ K+ + E+ +L A +E + EK+
Sbjct: 1246 AEGAAELG---EQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKL 1297
Score = 57.2 bits (132), Expect = 2e-07
Identities = 102/448 (22%), Positives = 197/448 (43%), Gaps = 47/448 (10%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
E AKLR E+ +V ++ R + + K + L+E R + ++ +L + +
Sbjct: 1464 EKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRES 1523
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R + ++ EA ++ +L K L+++ Q+ + ++E E T
Sbjct: 1524 RGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQEL----EKTK 1579
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
L ++ +QA + E + +E + K+ QLE L Q K E+ ++ E
Sbjct: 1580 KALEGEKSEIQAALEEAEGALE--LEETKTLRIQLE--LSQVK------AEVDRKLAEKD 1629
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI--DL-WAELQATKETLRVTED 460
E ++ + A+E LQA ++ E N L ++++ DL ELQ T + TE
Sbjct: 1630 EECANLRRNHQRAVESLQAS-LDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEA 1688
Query: 461 EVTTCKRE---KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
+ T + KE + +Q+LAAEL + + ++ R + +L E + E
Sbjct: 1689 QAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQ-----ALERRASLLAAELEELRA-ALE 1742
Query: 518 QYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL-LDVVHRNEELSEILAKKDQE 576
Q R + + + E N + Q+ +++ K KL D+ + E+ E A++ +E
Sbjct: 1743 QGERSRRLAEQELLEATERLNLLHSQN--TGLLNQKKKLEADLAQLSGEVEE-AAQERRE 1799
Query: 577 LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAK 636
E++ K + A + + EEL KE + S L +++ LE +R ++ A+
Sbjct: 1800 AEEKAKKAITDAAM--MAEEL-----KKEQDTSAHLERMKKTLEQTVR-------ELQAR 1845
Query: 637 ADEIQELFATLENKQQQIHRLEKIVLAL 664
+E ++ A L ++Q+ +LE V L
Sbjct: 1846 LEEAEQ--AALRGGKKQVQKLEAKVREL 1871
Score = 47.6 bits (108), Expect = 1e-04
Identities = 91/459 (19%), Positives = 193/459 (42%), Gaps = 36/459 (7%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+G + +++ +L+ E ++ R R+ E +A E EL EE + +L +E
Sbjct: 1149 LGAQMQKKIKELQARAEELEEELEAERAARARVEKQRA--EAAREL-EELSERL--EEAG 1203
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
+ Q R R A++ + RE E + TV L R+K+ + A +L E +
Sbjct: 1204 GASAGQREGCRKREAELGRLRRELEEAALRHEATVAAL----RRKQAE---GAAELGEQV 1256
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA---IQQLEEDLKQTKRALQE-Q 392
+ + +L +++ L+ EV + +E LT SA + E+ L + K ++E Q
Sbjct: 1257 DSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQ 1316
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE---REIDLWAELQ 449
++ + + R +TE + +EE + I +L + K E R+++ ++ +
Sbjct: 1317 RQLADASTQ-RGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAK 1375
Query: 450 -ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
A ++ + + + E E + + + N E + + + + + +L
Sbjct: 1376 SALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEEL 1435
Query: 509 NEQK---VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
E K ++ ++ ++A N ++ +++ LQ E D+ ++L R
Sbjct: 1436 EEAKKKLALRLQEAEEGVEAANAKCSSLEKAK-----LRLQTESEDVTLEL----ERATS 1486
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
+ L KK + LE+ + R Q ++ RE + + + EL L+ E +
Sbjct: 1487 AAAALDKKQRHLERALEERRRQEEEMQ-RE--LEAAQRESRGLGTELFRLRHGHEEALEA 1543
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
++ + ++ +EI +L + + I LEK AL
Sbjct: 1544 LETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKAL 1582
Score = 43.6 bits (98), Expect = 0.002
Identities = 57/279 (20%), Positives = 115/279 (41%), Gaps = 17/279 (6%)
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
R +E A M+ +L EE+ + + Q + R + + +L E A++
Sbjct: 1683 RQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALE 1742
Query: 306 SLTGTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
+ ++ E + + ++ L ++ L K E +QL + + E E ++
Sbjct: 1743 QGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEE 1802
Query: 363 QIEKLTVQHKSAIQQL--EEDLKQTKRALQEQCEITKREIE--LKERTETELQDSRNAIE 418
+ +K ++L E+D +++ E T RE++ L+E + L+ + ++
Sbjct: 1803 KAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQ 1862
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+L+AK+ ELE +L E++ A K RV E + +E +
Sbjct: 1863 KLEAKVRELE-----AELDAEQKKHAEALKGVRKHERRVKE----LAYQAEEDRKNLARM 1913
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
Q L +L +K + K Q + E N L + + Q+E
Sbjct: 1914 QDLVDKLQSKVKSY-KRQFEEAEQQANTNLAKYRKAQHE 1951
>AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 71.7 bits (168), Expect = 8e-12
Identities = 94/453 (20%), Positives = 200/453 (44%), Gaps = 36/453 (7%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
AL + +L Q VE +++ ++LR ++E K E +L +E A A ++K
Sbjct: 1068 ALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAA-QDK---- 1122
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+Q ++ K D +L + + ++L Q ++K +L+ARA +L E L+
Sbjct: 1123 ----QQLEEKLKKKDSELSQLSLRVED----EQLLGAQMQKKIKELQARAEELEEELEAE 1174
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
+++ +QR E+ E +++E+ + + ++ E +L + +R L+E
Sbjct: 1175 RAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRH 1234
Query: 397 KREIELKERTETE-LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ + R + E + ++ LQ +LEK K E+D A T
Sbjct: 1235 EATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSE----LRMEVDDLAANVETLTRA 1290
Query: 456 RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQ 515
+ + +++ ++ SE KI +++ L +L + G++Q ++ EL + ++ E + Q
Sbjct: 1291 KASAEKLCRTYEDQLSEAKIKVEE-LQRQLADASTQRGRLQTESGELSRLLEEKECLISQ 1349
Query: 516 YEQ----YVRDLQAHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEI 569
+ + L+ R + ++ + +++ Q L+ + L+ + + EL +
Sbjct: 1350 LSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRL 1409
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELIN-----VLKNKETEQSRELA-ALQQDLEHRM 623
L+K + E+ Q S+ +A I+ EEL L+ +E E+ E A A LE
Sbjct: 1410 LSKANAEVAQW--RSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAK 1467
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
+ ++ + + + A L+ KQ+ + R
Sbjct: 1468 LRLQTESEDVTLELERATSAAAALDKKQRHLER 1500
Score = 62.1 bits (144), Expect = 6e-09
Identities = 78/415 (18%), Positives = 191/415 (46%), Gaps = 39/415 (9%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTG-----TVKMLEDQSR-------- 319
+E+L ++LR R +A + + +E E + S+T +++ +Q
Sbjct: 895 EEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERC 954
Query: 320 ----QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI 375
+ +VQLE + ++L E L+ E + L +R L+ E E K+ I+ L + A
Sbjct: 955 HLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAE 1014
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQA---KIIELEKSKP 432
++ + + K +E + + L + + + + A+ +LQA ++ L K+K
Sbjct: 1015 KEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAK- 1073
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEII 492
L E++++ +L+ + E + + KR+ E + K+ Q+ +A +K+++
Sbjct: 1074 ---LRLEQQVE---DLECSLEQEKKLRMDTERAKRKLEGDLKL-TQESVADAAQDKQQLE 1126
Query: 493 GKMQIQTRELIK-NIKLNEQKVI--QYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI 549
K++ + EL + ++++ +++++ Q ++ +++LQA + E+ + ++++
Sbjct: 1127 EKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARAR-VEKQR 1185
Query: 550 MDLKMKLLDVVHRNEELSEILAKKDQELEQQDK---NSRGQARVIKIREE-LINVLKNKE 605
+ +L ++ R EE A + + +++ R + +R E + L+ K+
Sbjct: 1186 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 1245
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
E + EL + ++ R+ ++ K+ + E+ +L A +E + EK+
Sbjct: 1246 AEGAAELG---EQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKL 1297
Score = 57.2 bits (132), Expect = 2e-07
Identities = 102/448 (22%), Positives = 197/448 (43%), Gaps = 47/448 (10%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
E AKLR E+ +V ++ R + + K + L+E R + ++ +L + +
Sbjct: 1464 EKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRES 1523
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R + ++ EA ++ +L K L+++ Q+ + ++E E T
Sbjct: 1524 RGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQEL----EKTK 1579
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
L ++ +QA + E + +E + K+ QLE L Q K E+ ++ E
Sbjct: 1580 KALEGEKSEIQAALEEAEGALE--LEETKTLRIQLE--LSQVK------AEVDRKLAEKD 1629
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI--DL-WAELQATKETLRVTED 460
E ++ + A+E LQA ++ E N L ++++ DL ELQ T + TE
Sbjct: 1630 EECANLRRNHQRAVESLQAS-LDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEA 1688
Query: 461 EVTTCKRE---KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
+ T + KE + +Q+LAAEL + + ++ R + +L E + E
Sbjct: 1689 QAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQ-----ALERRASLLAAELEELRA-ALE 1742
Query: 518 QYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL-LDVVHRNEELSEILAKKDQE 576
Q R + + + E N + Q+ +++ K KL D+ + E+ E A++ +E
Sbjct: 1743 QGERSRRLAEQELLEATERLNLLHSQN--TGLLNQKKKLEADLAQLSGEVEE-AAQERRE 1799
Query: 577 LEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAK 636
E++ K + A + + EEL KE + S L +++ LE +R ++ A+
Sbjct: 1800 AEEKAKKAITDAAM--MAEEL-----KKEQDTSAHLERMKKTLEQTVR-------ELQAR 1845
Query: 637 ADEIQELFATLENKQQQIHRLEKIVLAL 664
+E ++ A L ++Q+ +LE V L
Sbjct: 1846 LEEAEQ--AALRGGKKQVQKLEAKVREL 1871
Score = 47.6 bits (108), Expect = 1e-04
Identities = 91/459 (19%), Positives = 193/459 (42%), Gaps = 36/459 (7%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
+G + +++ +L+ E ++ R R+ E +A E EL EE + +L +E
Sbjct: 1149 LGAQMQKKIKELQARAEELEEELEAERAARARVEKQRA--EAAREL-EELSERL--EEAG 1203
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
+ Q R R A++ + RE E + TV L R+K+ + A +L E +
Sbjct: 1204 GASAGQREGCRKREAELGRLRRELEEAALRHEATVAAL----RRKQAE---GAAELGEQV 1256
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA---IQQLEEDLKQTKRALQE-Q 392
+ + +L +++ L+ EV + +E LT SA + E+ L + K ++E Q
Sbjct: 1257 DSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQ 1316
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE---REIDLWAELQ 449
++ + + R +TE + +EE + I +L + K E R+++ ++ +
Sbjct: 1317 RQLADASTQ-RGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAK 1375
Query: 450 -ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
A ++ + + + E E + + + N E + + + + + +L
Sbjct: 1376 SALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEEL 1435
Query: 509 NEQK---VIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
E K ++ ++ ++A N ++ +++ LQ E D+ ++L R
Sbjct: 1436 EEAKKKLALRLQEAEEGVEAANAKCSSLEKAK-----LRLQTESEDVTLEL----ERATS 1486
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
+ L KK + LE+ + R Q ++ RE + + + EL L+ E +
Sbjct: 1487 AAAALDKKQRHLERALEERRRQEEEMQ-RE--LEAAQRESRGLGTELFRLRHGHEEALEA 1543
Query: 626 VDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
++ + ++ +EI +L + + I LEK AL
Sbjct: 1544 LETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKAL 1582
Score = 43.6 bits (98), Expect = 0.002
Identities = 57/279 (20%), Positives = 115/279 (41%), Gaps = 17/279 (6%)
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
R +E A M+ +L EE+ + + Q + R + + +L E A++
Sbjct: 1683 RQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALE 1742
Query: 306 SLTGTVKMLEDQ---SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
+ ++ E + + ++ L ++ L K E +QL + + E E ++
Sbjct: 1743 QGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEE 1802
Query: 363 QIEKLTVQHKSAIQQL--EEDLKQTKRALQEQCEITKREIE--LKERTETELQDSRNAIE 418
+ +K ++L E+D +++ E T RE++ L+E + L+ + ++
Sbjct: 1803 KAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQ 1862
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+L+AK+ ELE +L E++ A K RV E + +E +
Sbjct: 1863 KLEAKVRELE-----AELDAEQKKHAEALKGVRKHERRVKE----LAYQAEEDRKNLARM 1913
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE 517
Q L +L +K + K Q + E N L + + Q+E
Sbjct: 1914 QDLVDKLQSKVKSY-KRQFEEAEQQANTNLAKYRKAQHE 1951
>AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens
cDNA FLJ35908 fis, clone TESTI2009935. ).
Length = 550
Score = 71.7 bits (168), Expect = 8e-12
Identities = 98/515 (19%), Positives = 239/515 (46%), Gaps = 59/515 (11%)
Query: 147 ENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV----NTVTD 202
E ++ K + Q D + L + ++ +++ + + + +A++ + + +
Sbjct: 70 EIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVN 129
Query: 203 LSKRACHERRTLIAVGE-ALVREVAKLRQDV-ETRNVMIDEIRELR-SESENTKALEEMR 259
L+K E+ + +++ + + +R++ + +++V + R+ ++ E+ +LR S ++ T+ +E
Sbjct: 130 LTKLV--EQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETE 187
Query: 260 HELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR 319
+E A ++++ +++ + + K++K+L++ +A + S +K L+ +
Sbjct: 188 RSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQ 247
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE 379
+ + +L+ KL + LK ++ + ++ + Q + +Q+ E QH +QL
Sbjct: 248 KSKEELQ----KLEQQLKEQKILNERAAKELEQFQMRNAKLQQENE----QHSLVCEQLS 299
Query: 380 EDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
++ +Q + +ELK + E + +++ I +L K +
Sbjct: 300 QENQQ-------------KALELKAKEE--------EVHQMRLDIGKLNKIREQIHKKLH 338
Query: 440 REIDLWAELQATKETLRVTEDEVTTCKREKE-SENKIGIQQKLAAELLNKEEIIGKMQIQ 498
D AE++ KETL+ +++ +RE E S+ + + +K ELL + +I+ K ++
Sbjct: 339 HTEDQKAEVEQHKETLK---NQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLK 395
Query: 499 ----TRELIKNIKLNEQKVIQYE----QYVRDLQAHNRTIANCQESPNGISYQ--DLQQE 548
T++ +KL+EQ E Y + Q + I + ++ + Q DL Q+
Sbjct: 396 AVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQK 455
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQ 608
++ M + D+ R ++ + KK E E + K + ++ L + KN E
Sbjct: 456 VL---MNMEDIKVRETQIFD-YRKKIAESEIKLKQQQNLYEAVRSDRNLYS--KNL-VEA 508
Query: 609 SRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
E+ +++ L+ + VDE+ + I+AK + +L
Sbjct: 509 QDEITDMKRKLKIMIHQVDELKEDISAKESALVKL 543
Score = 49.2 bits (112), Expect = 5e-05
Identities = 75/364 (20%), Positives = 161/364 (44%), Gaps = 28/364 (7%)
Query: 294 DKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL--KTGEVTTSQLIQQRD 351
DK L + L +K +S E +L A+ R+L + + +V T+ + Q D
Sbjct: 33 DKSLEKFRIEYERLHAVMK----KSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDD 88
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE----LKERTE 407
Q + K++IEK SA + E+ K+T AL+E+ + +E L
Sbjct: 89 --QTTIASLKKEIEKAWKMVDSAYDK-EQKAKETILALKEEIVNLTKLVEQGSGLSMDQH 145
Query: 408 TELQDSRNAIEELQAK----IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
+ ++D EE+ + + E+ K + + TE++ + + + + + E+
Sbjct: 146 SNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQ 205
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+R+ E+ + ++KL EL + + Q + + L + ++ +++++ + EQ +++
Sbjct: 206 --QRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQ 263
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
+ N A E + LQQE + + N++ + L K++E+ Q +
Sbjct: 264 KILNERAAKELEQFQ-MRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 584 SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRM----RIVDEVNKQIAAKADE 639
++ KIRE++ L + E +Q E+ ++ L++++ R V+ KQ
Sbjct: 323 I---GKLNKIREQIHKKLHHTE-DQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKA 378
Query: 640 IQEL 643
+ EL
Sbjct: 379 MDEL 382
Score = 40.3 bits (90), Expect = 0.023
Identities = 64/296 (21%), Positives = 130/296 (43%), Gaps = 24/296 (8%)
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
V +SA +++E D + L + K IE ER ++ S + + L AK EL
Sbjct: 10 VLEESAFEEMERDFQGVLHELSGDKSLEKFRIEY-ERLHAVMKKSYDNEKRLMAKCRELN 68
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
EI + + AT L++++D+ TT K+ K K+ +K
Sbjct: 69 A-----------EIVVNSAKVAT--ALKLSQDDQTTIASLKKEIEKAW---KMVDSAYDK 112
Query: 489 EEIIGKMQIQTRELIKNI-KLNEQ-KVIQYEQY--VRDLQAHNRTIANCQESPNGISYQD 544
E+ + + +E I N+ KL EQ + +Q+ +RDL + ++
Sbjct: 113 EQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLS-EVVK 171
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ-QDKNSRGQARVIKIREELINVLKN 603
L++ + + + EE +++ QE++Q Q++ SR + K+ +EL + +
Sbjct: 172 LRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQAD 231
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
++ Q+ E+ ALQQ ++ + ++ +Q+ + + LE Q + +L++
Sbjct: 232 MDSRQT-EIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQ 286
>AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20-7
protein.
Length = 623
Score = 71.7 bits (168), Expect = 8e-12
Identities = 112/544 (20%), Positives = 245/544 (45%), Gaps = 36/544 (6%)
Query: 138 ELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAV 197
+L+ + +N+I+ + + + +T + E L ++ +L ++++ TQ E+
Sbjct: 6 KLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELR 65
Query: 198 NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE-----LRSESENT 252
+ A E ++ + KL+ +++ + I++ E L+ E
Sbjct: 66 EQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRV 125
Query: 253 KA-LEEMRHELDEERTAKLA-IKEK-LTTTESQL-RQTRNRVAKMDKQLREAEASITSLT 308
K + ++ + EE+ AKL + EK L E +L ++ + R + +Q++ A S +
Sbjct: 126 KQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEK--SQS 183
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
+K+ +++ +Q+ + LE + + L E L Q+ ++ + +LE + +EK
Sbjct: 184 EYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSL 243
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
++K+ + L L+ K + EIT + E+ +TEL+ ++ + L + +++
Sbjct: 244 QENKNQSKDLAVHLEAEKN--KHNMEIT----VMVEKHKTELESLKHQQDALWTEKLQVL 297
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE---NKIGIQQKLAAEL 485
K + ++ RE + + KETL ++ + E+ +E K+ ++Q L
Sbjct: 298 KQQYQTEMEKLRE-----KCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESL 352
Query: 486 LNKEEIIGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQD 544
++ + K + + E + +K K+ Q E + + + H++ + + +S Q
Sbjct: 353 SSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQR 412
Query: 545 LQQEIMDLKMKL-LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN 603
++ + D +L L + R++ L E A + LE K S G+ + + ++ ++
Sbjct: 413 TEKALKDQINQLELLLKERDKHLKEHQAHV-ENLEADIKRSEGELQQASAKLDVFQSYQS 471
Query: 604 KETEQSR----ELAALQQ---DLE-HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIH 655
EQ++ +LA LQQ DLE R+ + +V + A K D EL A Q +
Sbjct: 472 ATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQ 531
Query: 656 RLEK 659
+LEK
Sbjct: 532 QLEK 535
Score = 45.6 bits (103), Expect = 6e-04
Identities = 64/279 (22%), Positives = 131/279 (46%), Gaps = 30/279 (10%)
Query: 403 KERTETELQDSRNAIEEL-QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDE 461
K + T+L+D++N IE+L Q K + + ++K E + + A+L++ + + T+ E
Sbjct: 4 KTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQM-TTQGE 62
Query: 462 VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI-KLNEQKVIQYEQYV 520
++EK +K + EE K++ + E IK I K +E++ I +Q
Sbjct: 63 ELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ-- 120
Query: 521 RDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQ 580
+L + + + + + LQ K+ ++ + +EL++ L +++E ++Q
Sbjct: 121 -ELSRVKQEVVDVMKKSSEEQIAKLQ------KLHEKELARKEQELTKKLQTREREFQEQ 173
Query: 581 DKNS--RGQARVIKIR-----------EELINVLKNKETEQSRELAALQQDLE-HRMRIV 626
K + + Q+ +KI EEL K TE +L LQQ+ E +R RI+
Sbjct: 174 MKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRIL 233
Query: 627 D---EVNKQIAAKADEIQELFATLENKQQQIHRLEKIVL 662
+ + K + ++ ++L LE ++ + H +E V+
Sbjct: 234 ELESSLEKSLQENKNQSKDLAVHLEAEKNK-HNMEITVM 271
Score = 43.6 bits (98), Expect = 0.002
Identities = 50/200 (25%), Positives = 102/200 (51%), Gaps = 25/200 (12%)
Query: 242 IRELRSESENTKA-LEEMRHELDEERTAKLAIKEKL-TTTESQLRQTRNRVAKMDKQLRE 299
++E ++ EN +A ++ EL ++ +AKL + + + T Q + ++A++ ++L +
Sbjct: 435 LKEHQAHVENLEADIKRSEGEL-QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLD 493
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
E LT V +E Q +K+V E A K++ L+QQ L+ + E
Sbjct: 494 LETERILLTKQVAEVEAQ--KKDVCTELDAHKIQ---------VQDLMQQ---LEKQNSE 539
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ-------CEITKREIELKERTETELQD 412
+Q+++ LT ++S ++ ++ +QTK+ L E+ E K+EIE+ + + +D
Sbjct: 540 MEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKED 599
Query: 413 SRNAI-EELQAKIIELEKSK 431
S + + EE + K + +K K
Sbjct: 600 SIHILNEEYETKFKKKKKKK 619
Score = 33.1 bits (72), Expect = 3.4
Identities = 36/177 (20%), Positives = 77/177 (43%), Gaps = 5/177 (2%)
Query: 255 LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKML 314
L+E L E + ++ + +E +L+Q AK+D + +++ T +
Sbjct: 428 LKERDKHLKEHQAHVENLEADIKRSEGELQQAS---AKLDV-FQSYQSATHEQTKAYEEQ 483
Query: 315 EDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA 374
Q +QK + LE L + + E + + D+ + +V + QQ+EK + +
Sbjct: 484 LAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQK 543
Query: 375 IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD-SRNAIEELQAKIIELEKS 430
++ L + + ++ E TK+ + KE ++++ + IE L K+ E S
Sbjct: 544 VKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDS 600
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 71.7 bits (168), Expect = 8e-12
Identities = 101/483 (20%), Positives = 210/483 (43%), Gaps = 25/483 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 542 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 601
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 602 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 659
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + L + L +
Sbjct: 660 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 719
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ ++ L + + Q L L++ + LQ + E + E+E + +++ R+ +
Sbjct: 720 KKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 778
Query: 418 -EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESENK 474
EL+ LE++ + E AE Q + L + E T K+ +
Sbjct: 779 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 838
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ +L ++ N + + K++ + E + ++ N +++I+ + +L+ RT+
Sbjct: 839 VA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKMCRTLE 892
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ Q + + ++ Q+ + DL + + N ELS L +K+ + Q +RG+
Sbjct: 893 D-QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL---TRGKLTYT 948
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATLENK 650
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + + ++
Sbjct: 949 QQLEDLKRQLE-EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSE 1006
Query: 651 QQQ 653
Q
Sbjct: 1007 VAQ 1009
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 47/465 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
V + L +E ++ + +++ +++I + ++ E K + +++E R+ + +
Sbjct: 852 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE--KMCRTLEDQMNEHRSKAEETQRSV 909
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTV---KMLEDQSRQKEVQLEARARKL 332
SQ + + ++ +QL E EA I+ LT G + + LED RQ E +++A+ L
Sbjct: 910 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-NAL 968
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
+L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 969 AHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQRT 1022
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATK 452
E+ + + +L +R LQ++ A+E + AK LEK+K L E E DL +++ +
Sbjct: 1023 EELEEAKKKLAQR----LQEAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERSN 1075
Query: 453 ETLRVTE------DEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ D++ ++K ES++++ QK A L + + ++ E ++
Sbjct: 1076 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1135
Query: 505 NIKLNEQKVIQYE--QYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKL---- 556
K E K +Q E L + +TI ++ + + +LQ + + + L
Sbjct: 1136 TFK-RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1194
Query: 557 -------LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ E+ LA+KD+E+EQ +N RV+ + ++ E
Sbjct: 1195 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN---HLRVVDSLQTSLDAETRSRNEAL 1251
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R ++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 1252 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1296
Score = 65.7 bits (153), Expect = 5e-10
Identities = 82/438 (18%), Positives = 199/438 (45%), Gaps = 34/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E +KE L +E++ ++ ++ + ++ +
Sbjct: 474 KIKPLLKSAEREKEMASMKEEFTR-------LKEALEKSEARRKELEEKMVSLLQEKNDL 526
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 527 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 586
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 587 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 646
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 647 DDLQAEEDKVNTLTKAK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 699
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL-IKNIKLNEQKVI--QYEQYVRDLQAHNRTIA 531
+ Q+ + +K+++ +++ + EL N ++ +++ + Q ++ +++LQA +
Sbjct: 700 L-TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 758
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRG 586
E+ + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 759 EELEAER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRRD 816
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 817 LEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 873
Query: 647 LENKQQQIHRLEKIVLAL 664
+E + LEK+ L
Sbjct: 874 MEQIIKAKANLEKMCRTL 891
Score = 59.7 bits (138), Expect = 3e-08
Identities = 90/456 (19%), Positives = 190/456 (41%), Gaps = 38/456 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLT 277
+AL ++ K ++++ R ++E EL +E +E++R +L E ++E
Sbjct: 737 QALGSQLQKKLKELQARIEELEE--ELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 794
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
T Q+ + R A+ K R+ E + T L + +L + L+ +
Sbjct: 795 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 854
Query: 338 TGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
E S+ + D + + ++++ K +EK+ + + + ++T+R++ +
Sbjct: 855 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND--- 911
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQ 449
+T + +L +TE + ++E +A I +L + K DL + E ++ A+
Sbjct: 912 LTSQRAKL----QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-N 966
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
A L+ + + + E E + + + N E + + +T + + +L
Sbjct: 967 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1026
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
E K ++ +A A C + LQ EI DL ++DV R+ +
Sbjct: 1027 EAKKKLAQRLQEAEEAVEAVNAKCSSLEK--TKHRLQNEIEDL---MVDV-ERSNAAAAA 1080
Query: 570 LAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L KK + ++ + K Q+ + ++E ++ TE + A ++ LEH +
Sbjct: 1081 LDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFKLKNAYEESLEH-LE 1135
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
NK + +EI +L L + + IH LEK+
Sbjct: 1136 TFKRENKNLQ---EEISDLTEQLGSSGKTIHELEKV 1168
Score = 58.0 bits (134), Expect = 1e-07
Identities = 88/500 (17%), Positives = 214/500 (42%), Gaps = 30/500 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1081 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1139
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + I E+ ++R + E K ALEE L+ E L
Sbjct: 1140 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1199
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1200 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK-K 1255
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1256 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1314
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++ A
Sbjct: 1315 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMDA 1371
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEE----IIGKMQIQTRELIKN 505
L+ E+ V C+ +E K + AE L KE+ + +M+ + IK+
Sbjct: 1372 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1431
Query: 506 I--KLNEQKVIQY---EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
+ +L+E + I ++ ++ L+A R + N E+ + + + + + + ++ ++
Sbjct: 1432 LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESV-KGMRKSERRIKELT 1490
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
++ EE + L + +++ + R + EE N +K + EL + E
Sbjct: 1491 YQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL----DEAE 1546
Query: 621 HRMRIVDEVNKQIAAKADEI 640
R I + ++ AK+ +I
Sbjct: 1547 ERADIAESQVNKLRAKSRDI 1566
Score = 56.0 bits (129), Expect = 4e-07
Identities = 121/557 (21%), Positives = 234/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL + + EH S+ E
Sbjct: 850 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEHRSKAE----E 904
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
++ +L +Q +LS R E+ LI+ L R Q +E ++E
Sbjct: 905 TQRSVNDLTSQRAKLQTENGELS-RQLDEKEALIS---QLTRGKLTYTQQLEDLKRQLEE 960
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E+++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 961 --EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1018
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L+EAE ++ ++ LE + + ++E L ++
Sbjct: 1019 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1074
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1075 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1134
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + I ELEK + L E+ ++L + L+ + +L
Sbjct: 1135 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ--LEAEK-MELQSALEEAEASLE 1191
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEE-------IIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + E+ ++ +Q + +N
Sbjct: 1192 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 1250
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1251 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1305
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 1306 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1365
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 1366 KKKMDADLSQLQTEVEE 1382
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1275 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1333
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1334 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 1393
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1394 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1450
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1451 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1510
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1511 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1562
>AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2
protein.
Length = 1390
Score = 71.7 bits (168), Expect = 8e-12
Identities = 92/454 (20%), Positives = 205/454 (45%), Gaps = 23/454 (5%)
Query: 210 ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESE-NTKALEEMRHELDEERTA 268
E+RT A L REVA++RQ + + ++ R E E + ++L+ + ++ A
Sbjct: 893 EKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEA 952
Query: 269 KLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEAR 328
A+K+++ E ++ R + + +++R + +TS K ++ + + E +
Sbjct: 953 NEALKKQI---EELQQEARKAITEQKQKMRRLGSDLTSAQ---KEMKTKHKAYENAVGIL 1006
Query: 329 ARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRA 388
+R+L+E+L E ++L Q R Q + + + ++ +Q + ++
Sbjct: 1007 SRRLQEALAAKEAADAELGQLR--AQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE 1064
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
LQE +T +E+E EL+D + KI LE+S L E E L
Sbjct: 1065 LQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGL 1124
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
+ LR + T ++E++ + + ++ A L KEE +M+ + L +++
Sbjct: 1125 GQSNAALREHNSILETALAKREAD-LVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEK 1183
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-S 567
++KV ++ V A + N ++ E+ ++K +L H ++L +
Sbjct: 1184 EKEKVNSLKEQV--------AAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQA 1235
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
E + +E + + ++ QA + + R +L +L+ + EQ + Q++E+ VD
Sbjct: 1236 EADDLQIREGKHSQEIAQFQAELAEARAQL-QLLQKQLDEQLSKQPVGNQEMENLKWEVD 1294
Query: 628 EVNKQIAAKADEIQELFATLENKQQQIHRLEKIV 661
+ ++I + Q+L T + ++++ L++++
Sbjct: 1295 QKEREIQSLK---QQLDLTEQQGRKELEGLQQLL 1325
Score = 66.5 bits (155), Expect = 3e-10
Identities = 91/432 (21%), Positives = 196/432 (45%), Gaps = 36/432 (8%)
Query: 161 QDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA 220
Q + I E + G +L A +E+KT+ + N V LS+R + +A EA
Sbjct: 964 QQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRL----QEALAAKEA 1019
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTE 280
E+ +LR + + + +++ +A+ + L++E ++E + T
Sbjct: 1020 ADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKE------LQEVIALTS 1073
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+L ++R +V +++ +L+E+ +K LE+ +++ ++LE KL TG
Sbjct: 1074 QELEESREKVLELEDELQESR----GFRKKIKRLEESNKKLALELEHEKGKL-----TGL 1124
Query: 341 VTTSQLIQQRDS-LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK---RALQEQCEIT 396
++ +++ +S L+ + + + + +L +Q ++ +Q+ EE+ +Q K +ALQ E
Sbjct: 1125 GQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKE 1184
Query: 397 KREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
K ++ LKE+ ++ + +A +EL + K + + L +LQA + L
Sbjct: 1185 KEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKE----LQAKEHLVQKLQAEADDL 1240
Query: 456 RVTE----DEVTTCKRE-KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
++ E E+ + E E+ ++ + QK E L+K+ +G +++ + + K E
Sbjct: 1241 QIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQP-VGNQEMENLKWEVDQKERE 1299
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+ ++ + + + Q Q N S ++ QE DL M D ++SE+
Sbjct: 1300 IQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQE--DLSMTQKDKFMLQAKVSELK 1357
Query: 571 AKKDQELEQQDK 582
L+Q +
Sbjct: 1358 NNMKTLLQQNQQ 1369
Score = 63.3 bits (147), Expect = 3e-09
Identities = 116/564 (20%), Positives = 248/564 (43%), Gaps = 49/564 (8%)
Query: 126 DAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGA 185
++ A+ T E L++L E M +E ++ +L +Q + L+ +
Sbjct: 397 ESSAAETQEEMLQVLKEKMRLEGQLE--ALSLEASQALKEKAELQAQLAALSTKLQAQVE 454
Query: 186 LRELKTQAEDAVNTVTDLSKRACHE-RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
Q +D++++ D K++C + R + + L + A L V ++ +
Sbjct: 455 CSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQR 514
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
L ++ E+ + R L ++ T +++++T +SQL+Q + + +L+ ++A I
Sbjct: 515 LMAKVEDMQ-----RSMLSKDNTVH-DLRQQMTALQSQLQQVQLERTTLTSKLKASQAEI 568
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRE--SLKTGEVTTSQLIQ----QRDSLQAEVL 358
+SL + + +Q + EAR R E ++ G++T + L++ + SL ++
Sbjct: 569 SSLQSVRQWYQ---QQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLT 625
Query: 359 ECKQQIEKLTVQHKSAIQQLEED----------LKQTKRALQEQCEITKREIELKERTET 408
E + + K + + +Q +E D +++ K ++E + E E +
Sbjct: 626 ETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQ 685
Query: 409 ELQDSRNAIEEL--QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
+ DS ++E+ Q K+ L++ + L E +DL +L T+E L+ E + +
Sbjct: 686 RMADSAASLEQQLEQVKLTLLQRDQQLEALQQE-HLDLMKQLTLTQEALQSREQSLDALQ 744
Query: 467 RE-KESENKIGIQQKLAAE------LLNKEEIIGKMQIQT-----RELIKNIKLNEQKVI 514
E + ++G Q AA LL E+II + +Q EL + + E+
Sbjct: 745 THYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTE 804
Query: 515 QYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKD 574
+ + + L+ I + Q L++++ +K + L E KD
Sbjct: 805 ETSETLEKLR-EELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKD 863
Query: 575 QEL-EQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDL-EHRMRIVD-EVNK 631
Q + E + R + + ++R+EL+ V K T ++ EL+ L +++ + R + D E +
Sbjct: 864 QLISELKATRKRLDSELKELRQELMQVHGEKRTAEA-ELSRLHREVAQVRQHMADLEGHL 922
Query: 632 QIAAK-ADEIQELFATLENKQQQI 654
Q A K DE++ +L+ ++Q+
Sbjct: 923 QSAQKERDEMETHLQSLQFDKEQM 946
Score = 51.6 bits (118), Expect = 9e-06
Identities = 103/523 (19%), Positives = 224/523 (42%), Gaps = 58/523 (11%)
Query: 158 TVNQDQTDGDILEHLS-RYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
T+ Q + D+L+ + + DQG E+ G +R + D++ + L A + ++
Sbjct: 354 TLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRR----DSICSSVSLESSAAETQEEMLQ 409
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSE----SENTKALEEMRHELDEERTAKLAI 272
V + +R +L + + E EL+++ S +A E H + + + +
Sbjct: 410 VLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDS---L 466
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL 332
++ T + + + L AS+ S +++ E+Q ++ L A+ +
Sbjct: 467 SSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQR----LMAKVEDM 522
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE-EDLKQTKRALQE 391
+ S+ + + T L QQ +LQ+++ + Q+E+ T+ K Q E L+ ++ Q+
Sbjct: 523 QRSMLSKDNTVHDLRQQMTALQSQLQQV--QLERTTLTSKLKASQAEISSLQSVRQWYQQ 580
Query: 392 QCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQAT 451
Q + + E + R + E+ + + QA ++E K
Sbjct: 581 QLALAQ---EARVRLQGEMAHIQVG-QMTQAGLLEHLKL--------------------- 615
Query: 452 KETLRVTEDEVTTCKREKESENKIGIQ-QKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
E + +++ T R + + +I Q Q + A++L++E MQIQ + + L +
Sbjct: 616 -ENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAF--MQIQEAKTMVEEDL-Q 671
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ--QEIMDLKMKLLDVVHRNEELSE 568
+++ ++E LQ + A+ ++ + LQ Q++ L+ + LD++ + E
Sbjct: 672 RRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQE 731
Query: 569 ILAKKDQELEQ-QDKNSRGQARVIKI------REELINVLKNKETEQSRELAALQQDLEH 621
L ++Q L+ Q QAR+ ++ RE+ I +L+N++ L A + E
Sbjct: 732 ALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEE 791
Query: 622 RMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
R + + ++ +++L L K Q+ L++ AL
Sbjct: 792 LDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAAL 834
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 71.3 bits (167), Expect = 1e-11
Identities = 101/483 (20%), Positives = 210/483 (43%), Gaps = 25/483 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 963 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 1020
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + L + L +
Sbjct: 1021 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 1080
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ ++ L + + Q L L++ + LQ + E + E+E + +++ R+ +
Sbjct: 1081 KKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDL 1139
Query: 418 -EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESENK 474
EL+ LE++ + E AE Q + L + E T K+ +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ +L ++ N + + K++ + E + ++ N +++I+ + +L+ RT+
Sbjct: 1200 VA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKMCRTLE 1253
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ Q + + ++ Q+ + DL + + N ELS L +K+ + Q +RG+
Sbjct: 1254 D-QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL---TRGKLTYT 1309
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATLENK 650
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + + ++
Sbjct: 1310 QQLEDLKRQLE-EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSE 1367
Query: 651 QQQ 653
Q
Sbjct: 1368 VAQ 1370
Score = 66.9 bits (156), Expect = 2e-10
Identities = 83/438 (18%), Positives = 199/438 (45%), Gaps = 34/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E +KE L +E++ ++ ++ + ++ +
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTR-------LKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 947
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1007
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1008 DDLQAEEDKVNTLTKAK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL-IKNIKLNEQKVI--QYEQYVRDLQAHNRTIA 531
+ Q+ + +K+++ +++ + EL N ++ +++ + Q ++ +++LQA +
Sbjct: 1061 L-TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 1119
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRG 586
ES + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 1120 EELESER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRRD 1177
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 1178 LEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 647 LENKQQQIHRLEKIVLAL 664
+E + LEK+ L
Sbjct: 1235 MEQIIKAKANLEKMCRTL 1252
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 47/465 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
V + L +E ++ + +++ +++I + ++ E K + +++E R+ + +
Sbjct: 1213 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE--KMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTV---KMLEDQSRQKEVQLEARARKL 332
SQ + + ++ +QL E EA I+ LT G + + LED RQ E +++A+ L
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-NAL 1329
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
+L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 1330 AHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQRT 1383
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATK 452
E+ + + +L +R LQ++ A+E + AK LEK+K L E E DL +++ +
Sbjct: 1384 EELEEAKKKLAQR----LQEAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERSN 1436
Query: 453 ETLRVTE------DEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ D++ ++K ES++++ QK A L + + ++ E ++
Sbjct: 1437 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1496
Query: 505 NIKLNEQKVIQYE--QYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKL---- 556
K E K +Q E L + +TI ++ + + +LQ + + + L
Sbjct: 1497 TFK-RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 557 -------LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ E+ LA+KD+E+EQ +N RV+ + ++ E
Sbjct: 1556 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN---HLRVVDSLQTSLDAETRSRNEAL 1612
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R ++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 1613 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1657
Score = 60.9 bits (141), Expect = 1e-08
Identities = 91/456 (19%), Positives = 190/456 (41%), Gaps = 38/456 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLT 277
+AL ++ K ++++ R ++E EL SE +E++R +L E ++E
Sbjct: 1098 QALGSQLQKKLKELQARIEELEE--ELESERTARAKVEKLRSDLSRELEEISERLEEAGG 1155
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
T Q+ + R A+ K R+ E + T L + +L + L+ +
Sbjct: 1156 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 1215
Query: 338 TGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
E S+ + D + + ++++ K +EK+ + + + ++T+R++ +
Sbjct: 1216 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND--- 1272
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQ 449
+T + +L +TE + ++E +A I +L + K DL + E ++ A+
Sbjct: 1273 LTSQRAKL----QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-N 1327
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
A L+ + + + E E + + + N E + + +T + + +L
Sbjct: 1328 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1387
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
E K ++ +A A C + LQ EI DL ++DV R+ +
Sbjct: 1388 EAKKKLAQRLQEAEEAVEAVNAKCSSLEK--TKHRLQNEIEDL---MVDV-ERSNAAAAA 1441
Query: 570 LAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L KK + ++ + K Q+ + ++E ++ TE + A ++ LEH +
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFKLKNAYEESLEH-LE 1496
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
NK + +EI +L L + + IH LEK+
Sbjct: 1497 TFKRENKNLQ---EEISDLTEQLGSSGKTIHELEKV 1529
Score = 58.0 bits (134), Expect = 1e-07
Identities = 88/500 (17%), Positives = 214/500 (42%), Gaps = 30/500 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1500
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + I E+ ++R + E K ALEE L+ E L
Sbjct: 1501 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1561 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK-K 1616
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1617 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1675
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++ A
Sbjct: 1676 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMDA 1732
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEE----IIGKMQIQTRELIKN 505
L+ E+ V C+ +E K + AE L KE+ + +M+ + IK+
Sbjct: 1733 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1792
Query: 506 I--KLNEQKVIQY---EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
+ +L+E + I ++ ++ L+A R + N E+ + + + + + + ++ ++
Sbjct: 1793 LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESV-KGMRKSERRIKELT 1851
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
++ EE + L + +++ + R + EE N +K + EL + E
Sbjct: 1852 YQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL----DEAE 1907
Query: 621 HRMRIVDEVNKQIAAKADEI 640
R I + ++ AK+ +I
Sbjct: 1908 ERADIAESQVNKLRAKSRDI 1927
Score = 56.0 bits (129), Expect = 4e-07
Identities = 121/557 (21%), Positives = 234/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL + + EH S+ E
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEHRSKAE----E 1265
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
++ +L +Q +LS R E+ LI+ L R Q +E ++E
Sbjct: 1266 TQRSVNDLTSQRAKLQTENGELS-RQLDEKEALIS---QLTRGKLTYTQQLEDLKRQLEE 1321
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E+++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 1322 --EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L+EAE ++ ++ LE + + ++E L ++
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1435
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1436 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1495
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + I ELEK + L E+ ++L + L+ + +L
Sbjct: 1496 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ--LEAEK-MELQSALEEAEASLE 1552
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEE-------IIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + E+ ++ +Q + +N
Sbjct: 1553 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 1611
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1612 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1666
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1726
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 1727 KKKMDADLSQLQTEVEE 1743
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1636 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1695 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 1754
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1755 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1811
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1812 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1871
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1923
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 71.3 bits (167), Expect = 1e-11
Identities = 101/483 (20%), Positives = 210/483 (43%), Gaps = 25/483 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 963 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 1020
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + L + L +
Sbjct: 1021 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 1080
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ ++ L + + Q L L++ + LQ + E + E+E + +++ R+ +
Sbjct: 1081 KKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDL 1139
Query: 418 -EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESENK 474
EL+ LE++ + E AE Q + L + E T K+ +
Sbjct: 1140 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ +L ++ N + + K++ + E + ++ N +++I+ + +L+ RT+
Sbjct: 1200 VA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKMCRTLE 1253
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ Q + + ++ Q+ + DL + + N ELS L +K+ + Q +RG+
Sbjct: 1254 D-QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL---TRGKLTYT 1309
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATLENK 650
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + + ++
Sbjct: 1310 QQLEDLKRQLE-EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSE 1367
Query: 651 QQQ 653
Q
Sbjct: 1368 VAQ 1370
Score = 66.9 bits (156), Expect = 2e-10
Identities = 83/438 (18%), Positives = 199/438 (45%), Gaps = 34/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E +KE L +E++ ++ ++ + ++ +
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTR-------LKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 947
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1007
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1008 DDLQAEEDKVNTLTKAK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL-IKNIKLNEQKVI--QYEQYVRDLQAHNRTIA 531
+ Q+ + +K+++ +++ + EL N ++ +++ + Q ++ +++LQA +
Sbjct: 1061 L-TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 1119
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRG 586
ES + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 1120 EELESER-TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ-KMRRD 1177
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 1178 LEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 647 LENKQQQIHRLEKIVLAL 664
+E + LEK+ L
Sbjct: 1235 MEQIIKAKANLEKMCRTL 1252
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 47/465 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
V + L +E ++ + +++ +++I + ++ E K + +++E R+ + +
Sbjct: 1213 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE--KMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTV---KMLEDQSRQKEVQLEARARKL 332
SQ + + ++ +QL E EA I+ LT G + + LED RQ E +++A+ L
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-NAL 1329
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
+L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 1330 AHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQRT 1383
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATK 452
E+ + + +L +R LQ++ A+E + AK LEK+K L E E DL +++ +
Sbjct: 1384 EELEEAKKKLAQR----LQEAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERSN 1436
Query: 453 ETLRVTE------DEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ D++ ++K ES++++ QK A L + + ++ E ++
Sbjct: 1437 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1496
Query: 505 NIKLNEQKVIQYE--QYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKL---- 556
K E K +Q E L + +TI ++ + + +LQ + + + L
Sbjct: 1497 TFK-RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 557 -------LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ E+ LA+KD+E+EQ +N RV+ + ++ E
Sbjct: 1556 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN---HLRVVDSLQTSLDAETRSRNEAL 1612
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R ++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 1613 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1657
Score = 60.9 bits (141), Expect = 1e-08
Identities = 91/456 (19%), Positives = 190/456 (41%), Gaps = 38/456 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLT 277
+AL ++ K ++++ R ++E EL SE +E++R +L E ++E
Sbjct: 1098 QALGSQLQKKLKELQARIEELEE--ELESERTARAKVEKLRSDLSRELEEISERLEEAGG 1155
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
T Q+ + R A+ K R+ E + T L + +L + L+ +
Sbjct: 1156 ATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 1215
Query: 338 TGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
E S+ + D + + ++++ K +EK+ + + + ++T+R++ +
Sbjct: 1216 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND--- 1272
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQ 449
+T + +L +TE + ++E +A I +L + K DL + E ++ A+
Sbjct: 1273 LTSQRAKL----QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-N 1327
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
A L+ + + + E E + + + N E + + +T + + +L
Sbjct: 1328 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1387
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
E K ++ +A A C + LQ EI DL ++DV R+ +
Sbjct: 1388 EAKKKLAQRLQEAEEAVEAVNAKCSSLEK--TKHRLQNEIEDL---MVDV-ERSNAAAAA 1441
Query: 570 LAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L KK + ++ + K Q+ + ++E ++ TE + A ++ LEH +
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFKLKNAYEESLEH-LE 1496
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
NK + +EI +L L + + IH LEK+
Sbjct: 1497 TFKRENKNLQ---EEISDLTEQLGSSGKTIHELEKV 1529
Score = 58.0 bits (134), Expect = 1e-07
Identities = 88/500 (17%), Positives = 214/500 (42%), Gaps = 30/500 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1500
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + I E+ ++R + E K ALEE L+ E L
Sbjct: 1501 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1561 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK-K 1616
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1617 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1675
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++ A
Sbjct: 1676 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMDA 1732
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEE----IIGKMQIQTRELIKN 505
L+ E+ V C+ +E K + AE L KE+ + +M+ + IK+
Sbjct: 1733 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1792
Query: 506 I--KLNEQKVIQY---EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
+ +L+E + I ++ ++ L+A R + N E+ + + + + + + ++ ++
Sbjct: 1793 LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESV-KGMRKSERRIKELT 1851
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
++ EE + L + +++ + R + EE N +K + EL + E
Sbjct: 1852 YQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL----DEAE 1907
Query: 621 HRMRIVDEVNKQIAAKADEI 640
R I + ++ AK+ +I
Sbjct: 1908 ERADIAESQVNKLRAKSRDI 1927
Score = 56.0 bits (129), Expect = 4e-07
Identities = 121/557 (21%), Positives = 234/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL + + EH S+ E
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEHRSKAE----E 1265
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
++ +L +Q +LS R E+ LI+ L R Q +E ++E
Sbjct: 1266 TQRSVNDLTSQRAKLQTENGELS-RQLDEKEALIS---QLTRGKLTYTQQLEDLKRQLEE 1321
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E+++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 1322 --EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L+EAE ++ ++ LE + + ++E L ++
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1435
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1436 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1495
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + I ELEK + L E+ ++L + L+ + +L
Sbjct: 1496 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ--LEAEK-MELQSALEEAEASLE 1552
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEE-------IIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + E+ ++ +Q + +N
Sbjct: 1553 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 1611
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1612 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1666
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1726
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 1727 KKKMDADLSQLQTEVEE 1743
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1636 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1695 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 1754
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1755 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1811
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1812 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1871
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1923
>D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein.
Length = 709
Score = 71.3 bits (167), Expect = 1e-11
Identities = 99/438 (22%), Positives = 197/438 (44%), Gaps = 37/438 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLT 277
+ L+ L +E D++ EL E+ KA L +M E D +R + E+
Sbjct: 279 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 338
Query: 278 TTESQLRQTRNRVAKMDKQLRE-------AEASITSLTGTVKMLEDQSRQKEVQLEARA- 329
T E +Q+ + + +L + +EA SL V L SR ++++E ++
Sbjct: 339 TLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTS-SRLLKLEMENQSL 397
Query: 330 ----RKLRESLKTGEVTTSQLIQ-----QRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
+LR ++ + E S++++ QR S + E+LE + EK ++Q+ Q L +
Sbjct: 398 TKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN---CQNLSK 454
Query: 381 DLKQTKRALQEQCEI----TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL 436
DL + K L++ E ++R+I++ E+ L + +++ + +++I + K D+
Sbjct: 455 DLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ-RSQISAEARVK---DI 510
Query: 437 PTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ 496
E +I L ++ T L E E K+E E + G + A EL N+ + K
Sbjct: 511 EKENKI-LHESIKETSSKLSKIEFEKRQIKKELEHYKEKG---ERAEELENELHHLEKEN 566
Query: 497 IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKM 554
++ I N+K+ +K+ EQ +L+ NR + +S +++Q L++E L
Sbjct: 567 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 626
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
+ L+ + RN E + + K +L+ ++K + +K EL+ K
Sbjct: 627 ENLE-LRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG 685
Query: 615 LQQDLEHRMRIVDEVNKQ 632
L + + + ++ NK+
Sbjct: 686 LDIENQRLQKTLENSNKK 703
Score = 57.6 bits (133), Expect = 1e-07
Identities = 88/431 (20%), Positives = 190/431 (44%), Gaps = 31/431 (7%)
Query: 241 EIRELRSE-SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+IR LR E E T+ L + + EL++ ++++ S R R ++D LRE
Sbjct: 184 KIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDA-LRE 242
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
+ L V +++ E +AR +L+E + T + L Q + +A +
Sbjct: 243 KAVRVDKLESEVSRYKERLHDIEFY-KARVEELKEDNQVLLETKTMLEDQLEGTRARS-D 300
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEE 419
++EK +Q K+ + +E + ++ ++E E + L+ + + +S + E
Sbjct: 301 KLHELEKENLQLKAKLHDMEMERDMDRKKIEELME---ENMTLEMAQKQSMDESLHLGWE 357
Query: 420 LQ--AKIIELEKSKPNPDLPTE-REI--DLWAELQATKETLRVTEDEV-TTCKREKESEN 473
L+ ++ EL ++ P L E E+ +L+ ++L T +E+ TT + + +
Sbjct: 358 LEQISRTSELSEA-PQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNAS 416
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK-----LNEQKVIQYEQYVRDLQAHNR 528
KI +K L K EI+ +Q ++ ++N + L ++K Q E+ + L+ ++
Sbjct: 417 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA-QLEKTIETLRENSE 475
Query: 529 TIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQA 588
E N + L Q + L+ + + + +I K+++ L + K + +
Sbjct: 476 RQIKILEQEN----EHLNQTVSSLRQR--SQISAEARVKDI-EKENKILHESIKETSSKL 528
Query: 589 RVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
I+ + I KE E +E ++LE+ + +++ N+ + K ++ +E
Sbjct: 529 SKIEFEKRQIK----KELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIE 584
Query: 649 NKQQQIHRLEK 659
+Q+ LE+
Sbjct: 585 ALEQENSELER 595
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/433 (17%), Positives = 189/433 (43%), Gaps = 27/433 (6%)
Query: 231 DVETRNVMIDEIRELRSESENTKALEEMR-HELDEERTAKLAIKEKLTTTESQLRQTRNR 289
D +T+ + I+E+ EN L+ M ++ +E L + + +L R+
Sbjct: 74 DFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLL--KNMALHLKRLIDERDE 131
Query: 290 VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
++ +L E + L + ++ + L L + +L Q+
Sbjct: 132 HSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQE 191
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--RALQEQCEITKREIELKERTE 407
+ ++L+CKQ++E++ ++ K Q+ L + R +++ + + + ++ E
Sbjct: 192 LEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLE 251
Query: 408 TELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
+E+ + + +++ +E+ K + + E + L +L+ T R D++
Sbjct: 252 SEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT----RARSDKL----H 303
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
E E EN + ++ KL + ++ K++ E + +Q + + +L+ +
Sbjct: 304 ELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 362
Query: 528 RTIANCQESPNGISYQDLQQEIMDL-KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRG 586
RT + E+P + L E+ +L +LL + N+ L++ + + ++ + N+
Sbjct: 363 RT-SELSEAPQ----KSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA-- 415
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
++++K+ +E + K E ++ E+ +Q L++ + ++ K+ A I+ L
Sbjct: 416 -SKILKMEKENQRLSKKVEILEN-EIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETL--- 470
Query: 647 LENKQQQIHRLEK 659
EN ++QI LE+
Sbjct: 471 RENSERQIKILEQ 483
>AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransferase
9 protein.
Length = 978
Score = 71.3 bits (167), Expect = 1e-11
Identities = 80/401 (19%), Positives = 189/401 (47%), Gaps = 31/401 (7%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALV-REVAKLRQDVETRNVMIDEIRE 244
L + KT+ E N V +L K H T + EAL REV + E +N +
Sbjct: 588 LDQTKTELEKKTNAVKELEKLQ-HSTETELT--EALQKREVL----ETELQNAHGELKST 640
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
LR E L++ + L+E+ T + +L + ++ + + +MD+ L+E +
Sbjct: 641 LRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDEKQELLEMDQALKERNWEL 700
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
V L+ R+ ++E + KL +L+ E+ + +Q +SL ++ K+Q+
Sbjct: 701 KQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQL 760
Query: 365 ---EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
E + +Q++ I QL++++++T++ ++E + K E ++ T+ +++ + ++L+
Sbjct: 761 REKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMK---EQEQYIATQCKEAIDLGQKLR 817
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE--DEVTTCKREKESENKIGIQQ 479
+++ S + +L R ++QA +E R++ +++ +EK++ + +
Sbjct: 818 LTREQVQNS--HTELAEARH----QQVQAQREIERLSSELEDMKQLSKEKDAHGN-HLAE 870
Query: 480 KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNG 539
+L A + + + +MQ + ++L ++ + E Y ++ +H A + S +
Sbjct: 871 ELGASKVREAHLEARMQAEIKKLSAEVESLK------EAYHMEMISHQENHAKWKISADS 924
Query: 540 --ISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELE 578
S Q L +++ K++L + L + + +++ +E
Sbjct: 925 QKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIE 965
Score = 65.3 bits (152), Expect = 7e-10
Identities = 83/449 (18%), Positives = 200/449 (44%), Gaps = 27/449 (6%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
++V +L + +D+ +E S+ E K + ++ + + + + L T+++
Sbjct: 537 QKVIELTGTARQVKIEMDQYKEELSKME--KEIMHLKRDGENKAMHFSQLDMILDQTKTE 594
Query: 283 LRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKL---RESLKTG 339
L + N V +++K E +T ++LE + + +L++ R+L R+ L+
Sbjct: 595 LEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKA 654
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC-EITKR 398
+++ + L AE+ ECK +IE K + ++++ LK+ L+++ ++T
Sbjct: 655 QLSLEEKYTTIKDLTAELRECKMEIE----DEKQELLEMDQALKERNWELKQRAAQVTHL 710
Query: 399 EIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
++ ++E E++ +E K ELE + N + + + A+ Q ++ +
Sbjct: 711 DMTIREH-RGEMEQKIIKLEGTLEKS-ELELKECNKQIESLNDKLQNAKEQLREKEFIML 768
Query: 459 EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ 518
++E + +KE E +++ + + +E+ I + +L + ++L ++V
Sbjct: 769 QNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQCKEAIDLGQKLRLTREQV--QNS 826
Query: 519 YVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEELSEILAKKDQEL 577
+ +A ++ + +E + L E+ D+K + H N E+ A K +E
Sbjct: 827 HTELAEARHQQVQAQRE------IERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREA 880
Query: 578 EQQDKNSRGQARVIKIREELINVLKNKETEQ---SRELAALQQDLEHRMRIVDEVNKQIA 634
+ +R QA + K+ E+ ++ + E A + + + V ++N+Q+
Sbjct: 881 HLE---ARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLE 937
Query: 635 AKADEIQELFATLENKQQQIHRLEKIVLA 663
E++E T+ N QQ+ +++ A
Sbjct: 938 KAKLELEEAQDTVSNLHQQVQDRNEVIEA 966
Score = 63.3 bits (147), Expect = 3e-09
Identities = 87/418 (20%), Positives = 180/418 (43%), Gaps = 43/418 (10%)
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLR----EAEASITSLT 308
+ L E + E+ +E K E L ++Q+ + +V ++D L E + L
Sbjct: 371 RLLTESKGEMKKENMKK---DEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLE 427
Query: 309 GTVKMLEDQSRQK-------EVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVL--- 358
G + E Q ++K + +L+ + L+E+ + + L QQ+ LQ E +
Sbjct: 428 GNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNG 487
Query: 359 ---ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
+ + ++EK + + +Q+ E + R ++E+CE E +LK + EL +
Sbjct: 488 ELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTAR 547
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
++ IE+++ K E+EI + + + + ++ ++ + + E E K
Sbjct: 548 QVK------IEMDQYKEELS-KMEKEI-MHLKRDGENKAMHFSQLDMILDQTKTELEKKT 599
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
++L +L + E +Q RE+++ N + + +R LQ + Q
Sbjct: 600 NAVKEL-EKLQHSTETELTEALQKREVLETELQNAHG--ELKSTLRQLQELRDVLQKAQL 656
Query: 536 S--PNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKI 593
S + +DL E+ + KM++ D E+ + L +++ EL+Q+ A+V
Sbjct: 657 SLEEKYTTIKDLTAELRECKMEIEDEKQELLEMDQALKERNWELKQR------AAQV--- 707
Query: 594 REELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
L ++ E +++ L+ LE + E NKQI + D++Q L K+
Sbjct: 708 -THLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKE 764
Score = 60.1 bits (139), Expect = 3e-08
Identities = 86/501 (17%), Positives = 209/501 (41%), Gaps = 29/501 (5%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSES------ENTK---ALEEMRHELDEERTAKLAIK 273
+ ++ L+QD+ + ++ + L +ES EN K AL+ +++++ EE +
Sbjct: 350 KTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLD 409
Query: 274 EKLTTTESQL----RQTRNRVAKMDKQLREAEASITSLTGTVKMLE---DQSRQKEVQLE 326
L + +L Q K +KQL++ + L +K+ ++ ++ V L+
Sbjct: 410 SALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQ 469
Query: 327 ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK 386
++ ++ L+ + +L + L+ +V + +Q+++K Q +S+ ++L + ++ +
Sbjct: 470 HTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQK---QRESSAEKLRKMEEKCE 526
Query: 387 RALQEQCEITKREIELK---ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREID 443
A E ++ IEL + + E+ + + +++ +I+ L++ N + ++D
Sbjct: 527 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHFS-QLD 585
Query: 444 LWAELQAT---KETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
+ + T K+T V E E E E + ++ L EL N + Q +
Sbjct: 586 MILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQ 645
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA-NCQESPNGISYQD--LQQEIMDLKMKLL 557
EL ++ + + + ++DL A R ++ + D L++ +LK +
Sbjct: 646 ELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDEKQELLEMDQALKERNWELKQRAA 705
Query: 558 DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ 617
V H + + E + +Q++ + + +K + I L +K +L +
Sbjct: 706 QVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEF 765
Query: 618 DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXX 677
+ + + ++ K+I ++E+ + ++ ++Q I K + L
Sbjct: 766 IMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQCKEAIDLGQKLRLTREQVQN 825
Query: 678 XXXKIAALEHELAAGLNRKER 698
++A H+ ER
Sbjct: 826 SHTELAEARHQQVQAQREIER 846
Score = 50.0 bits (114), Expect = 3e-05
Identities = 65/319 (20%), Positives = 141/319 (44%), Gaps = 25/319 (7%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSK--RACH-----ERRTLIAVGEALVREVAKLRQDVE 233
EL L++ + E+ T+ DL+ R C E++ L+ + +AL +L+Q
Sbjct: 646 ELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDEKQELLEMDQALKERNWELKQRAA 705
Query: 234 TRNVMIDEIRELRSESEN-----TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
+ IRE R E E LE+ EL E ++ +KL + QLR+
Sbjct: 706 QVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEF 765
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQ 348
+ + ++++ + + I +K +E +++E + + ++ + + +T Q+
Sbjct: 766 IMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQCKEAIDLGQKLRLTREQVQN 825
Query: 349 QRDSL---QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK-REIELKE 404
L + + ++ +++IE+L+ + + ++QL ++ L E+ +K RE L+
Sbjct: 826 SHTELAEARHQQVQAQREIERLSSELED-MKQLSKEKDAHGNHLAEELGASKVREAHLEA 884
Query: 405 RTETELQDSRNAIEEL-QAKIIEL-------EKSKPNPDLPTEREIDLWAELQATKETLR 456
R + E++ +E L +A +E+ K K + D L +L+ K L
Sbjct: 885 RMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELE 944
Query: 457 VTEDEVTTCKREKESENKI 475
+D V+ ++ + N++
Sbjct: 945 EAQDTVSNLHQQVQDRNEV 963
Score = 43.6 bits (98), Expect = 0.002
Identities = 84/435 (19%), Positives = 178/435 (40%), Gaps = 32/435 (7%)
Query: 228 LRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTR 287
+ Q E+R ++ EL ++ E + + +E E + A E+L + ++ +R
Sbjct: 9 MAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSR 68
Query: 288 NRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT--GEVTTSQ 345
+ ++K + + L G L E R E+ K E+
Sbjct: 69 VELRSLEKIISQLPLK-RELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKL 127
Query: 346 LIQQRDSLQAEVLECKQQIEKLTV-----QHKSAIQQLE-EDLKQTKRALQEQCEITKRE 399
I++ + + Q+ + + Q S + LE E +K + E + + +
Sbjct: 128 AIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVK-DQNQ 186
Query: 400 IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE 459
+ ++ E E Q IEEL+ K+I++E N DL ++ Q +E L E
Sbjct: 187 HTMNKQYEKERQRLVTGIEELRTKLIQIEAE--NSDLKVNMA-HRTSQFQLIQEEL--LE 241
Query: 460 DEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
+ K E E K Q L E +E+I+ I KN +L EQ++++ +
Sbjct: 242 KASNSSKLESEMTKKCS--QLLTLEKQLEEKIVAYSSIAA----KNAEL-EQELMEKNEK 294
Query: 520 VRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
+R L+ T N + ++++ ++ ++ ++ + R L L KKDQ+ ++
Sbjct: 295 IRSLE----TNINTEHEKICLAFEKAKKIHLEQHKEMEKQIER---LEAQLEKKDQQFKE 347
Query: 580 QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADE 639
Q+K + I ++ + L TE E+ + ++ + Q++ + +
Sbjct: 348 QEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALK---ALQNQVSEETIK 404
Query: 640 IQELFATLENKQQQI 654
+++L + LE ++++
Sbjct: 405 VRQLDSALEICKEEL 419
Score = 33.9 bits (74), Expect = 2.0
Identities = 58/333 (17%), Positives = 131/333 (39%), Gaps = 21/333 (6%)
Query: 370 QHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEK 429
+ + +I +LE +L+ L+++ + ELK R + + +E+++ +EL
Sbjct: 14 ESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRS 73
Query: 430 -SKPNPDLPTEREIDLWAELQATKETLRVTEDE---VTTCKREKESENKIGIQQKL-AAE 484
K LP +RE+ + + + + E + C+ K +++ I+ + AE
Sbjct: 74 LEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAE 133
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN--RTIANCQESPNGISY 542
+ + Q+ + N K+ E L H ++ + + Y
Sbjct: 134 IQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQY 193
Query: 543 QDLQQEIM----DLKMKLLDVVHRNEELSEILAKKDQELEQ-QDKNSRGQARVIKIREEL 597
+ +Q ++ +L+ KL+ + N +L +A + + + Q++ + K+ E+
Sbjct: 194 EKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEM 253
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIH-R 656
T++ +L L++ LE ++ + + A E+ E + + + I+
Sbjct: 254 --------TKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTE 305
Query: 657 LEKIVLALXXXXXXXXXXXXXXXXKIAALEHEL 689
EKI LA +I LE +L
Sbjct: 306 HEKICLAFEKAKKIHLEQHKEMEKQIERLEAQL 338
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 70.9 bits (166), Expect = 1e-11
Identities = 101/483 (20%), Positives = 209/483 (43%), Gaps = 25/483 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMID 240
E C L + K Q E V + + + L A L E ++L++D++ + +
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 241 EIRELRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDK--QL 297
++ + + +EN K L E LD E AKL KEK E+ + + A+ DK L
Sbjct: 963 KVEKEKHATENKVKNLTEEMAGLD-EIIAKLT-KEKKALQEAHQQALDDLQAEEDKVNTL 1020
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+A+ + ++ +Q ++ + LE RKL LK + + L + L +
Sbjct: 1021 TKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL 1080
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
+ ++ L + + Q L L++ + LQ + E + E+E + +++ R+ +
Sbjct: 1081 KKKDFELNALNARIEDE-QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 418 -EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESENK 474
EL+ LE++ E AE Q + L + E T K+ +
Sbjct: 1140 SRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1199
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL---IKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ +L ++ N + + K++ + E + ++ N +++I+ + +L+ RT+
Sbjct: 1200 VA---ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAK---ANLEKMCRTLE 1253
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
+ Q + + ++ Q+ + DL + + N ELS L +K+ + Q +RG+
Sbjct: 1254 D-QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL---TRGKLTYT 1309
Query: 592 KIREELINVLKNKETEQSRELAALQQDLEHRMRIV-DEVNKQIAAKADEIQELFATLENK 650
+ E+L L+ +E + LA Q H ++ ++ ++ AKA E+Q + + ++
Sbjct: 1310 QQLEDLKRQLE-EEVKAKNALAHALQSARHDCDLLREQYEEETEAKA-ELQRVLSKANSE 1367
Query: 651 QQQ 653
Q
Sbjct: 1368 VAQ 1370
Score = 66.9 bits (156), Expect = 2e-10
Identities = 98/465 (21%), Positives = 205/465 (44%), Gaps = 47/465 (10%)
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKL 276
V + L +E ++ + +++ +++I + ++ E K + +++E R+ + +
Sbjct: 1213 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE--KMCRTLEDQMNEHRSKAEETQRSV 1270
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTV---KMLEDQSRQKEVQLEARARKL 332
SQ + + ++ +QL E EA I+ LT G + + LED RQ E +++A+ L
Sbjct: 1271 NDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-NAL 1329
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
+L++ L +Q + E E K +++++ + S + Q K A+Q
Sbjct: 1330 AHALQSARHDCDLLREQYE----EETEAKAELQRVLSKANSEVAQWRT--KYETDAIQRT 1383
Query: 393 CEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATK 452
E+ + + +L +R LQ++ A+E + AK LEK+K L E E DL +++ +
Sbjct: 1384 EELEEAKKKLAQR----LQEAEEAVEAVNAKCSSLEKTKHR--LQNEIE-DLMVDVERSN 1436
Query: 453 ETLRVTE------DEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK 504
+ D++ ++K ES++++ QK A L + + ++ E ++
Sbjct: 1437 AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE 1496
Query: 505 NIKLNEQKVIQYE--QYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKL---- 556
K E K +Q E L + +TI ++ + + +LQ + + + L
Sbjct: 1497 TFK-RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEE 1555
Query: 557 -------LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ E+ LA+KD+E+EQ +N RV+ + ++ E
Sbjct: 1556 GKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN---HLRVVDSLQTSLDAETRSRNEAL 1612
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
R ++ DL + N+ A +++ L + L++ Q Q+
Sbjct: 1613 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1657
Score = 65.7 bits (153), Expect = 5e-10
Identities = 82/438 (18%), Positives = 199/438 (45%), Gaps = 34/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+I+ L +E K + M+ E +KE L +E++ ++ ++ + ++ +
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTR-------LKEALEKSEARRKELEEKMVSLLQEKNDL 887
Query: 301 EASITSLTGTVKMLE---DQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
+ + + + E DQ + ++QLEA+ +++ E L+ E ++L ++ L+ E
Sbjct: 888 QLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDEC 947
Query: 358 LECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI 417
E K+ I+ L + ++ + K +E + + +L + + + + A+
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1007
Query: 418 EELQA---KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENK 474
++LQA K+ L K+K + E+++D +L+ + E + ++ KR+ E + K
Sbjct: 1008 DDLQAEEDKVNTLTKAK----VKLEQQVD---DLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 475 IGIQQKLAAELLNKEEIIGKMQIQTREL-IKNIKLNEQKVI--QYEQYVRDLQAHNRTIA 531
+ Q+ + +K+++ +++ + EL N ++ +++ + Q ++ +++LQA +
Sbjct: 1061 L-TQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 1119
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS-----EILAKKDQELEQQDKNSRG 586
E+ + +++ DL +L ++ R EE +I K +E E Q K R
Sbjct: 1120 EELEAER-TARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQ-KMRRD 1177
Query: 587 QARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFAT 646
E L+ K + +A L + +++ R+ ++ K+ + E+ ++ +
Sbjct: 1178 LEEATLQHEATAAALRKKHAD---SVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 647 LENKQQQIHRLEKIVLAL 664
+E + LEK+ L
Sbjct: 1235 MEQIIKAKANLEKMCRTL 1252
Score = 60.1 bits (139), Expect = 3e-08
Identities = 90/456 (19%), Positives = 190/456 (41%), Gaps = 38/456 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLT 277
+AL ++ K ++++ R ++E EL +E +E++R +L E ++E
Sbjct: 1098 QALGSQLQKKLKELQARIEELEE--ELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 1155
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
T Q+ + R A+ K R+ E + T L + +L + L+ +
Sbjct: 1156 ATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQ 1215
Query: 338 TGEVTTSQLIQQRDSLQA---EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
E S+ + D + + ++++ K +EK+ + + + ++T+R++ +
Sbjct: 1216 KLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND--- 1272
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN-----PDLPTEREIDLWAELQ 449
+T + +L +TE + ++E +A I +L + K DL + E ++ A+
Sbjct: 1273 LTSQRAKL----QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK-N 1327
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLN 509
A L+ + + + E E + + + N E + + +T + + +L
Sbjct: 1328 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1387
Query: 510 EQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI 569
E K ++ +A A C + LQ EI DL ++DV R+ +
Sbjct: 1388 EAKKKLAQRLQEAEEAVEAVNAKCSSLEK--TKHRLQNEIEDL---MVDV-ERSNAAAAA 1441
Query: 570 LAKKDQELEQ-----QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L KK + ++ + K Q+ + ++E ++ TE + A ++ LEH +
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTELFKLKNAYEESLEH-LE 1496
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
NK + +EI +L L + + IH LEK+
Sbjct: 1497 TFKRENKNLQ---EEISDLTEQLGSSGKTIHELEKV 1529
Score = 58.0 bits (134), Expect = 1e-07
Identities = 88/500 (17%), Positives = 214/500 (42%), Gaps = 30/500 (6%)
Query: 157 LTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIA 216
L Q D + E +Y + EL + +E ++ + + + + + + T
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK-LKNAYEESLEHLETFKR 1500
Query: 217 VGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-----ALEEMRHELDEERTAKLA 271
+ L E++ L + + + I E+ ++R + E K ALEE L+ E L
Sbjct: 1501 ENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILR 1560
Query: 272 IKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM-LEDQSRQKEVQLEARAR 330
+ + ++++ + ++A+ D+++ +A+ + + +++ L+ ++R + L + +
Sbjct: 1561 AQLEFNQIKAEIER---KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVK-K 1616
Query: 331 KLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQ 390
K+ L E+ S + Q +V + ++ +Q A++ +DLK+ ++
Sbjct: 1617 KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA-NDDLKENIAIVE 1675
Query: 391 EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
+ + + E+E + + SR E+ ++IE + I+ ++ A
Sbjct: 1676 RRNNLLQAELEELRAVVEQTERSRKLAEQ---ELIETSERVQLLHSQNTSLINQKKKMDA 1732
Query: 451 TKETLRV-TEDEVTTCKREKESENKIGIQQKLAAELLNKEE----IIGKMQIQTRELIKN 505
L+ E+ V C+ +E K + AE L KE+ + +M+ + IK+
Sbjct: 1733 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1792
Query: 506 I--KLNEQKVIQY---EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
+ +L+E + I ++ ++ L+A R + N E+ + + + + + + ++ ++
Sbjct: 1793 LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESV-KGMRKSERRIKELT 1851
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
++ EE + L + +++ + R + EE N +K + EL + E
Sbjct: 1852 YQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL----DEAE 1907
Query: 621 HRMRIVDEVNKQIAAKADEI 640
R I + ++ AK+ +I
Sbjct: 1908 ERADIAESQVNKLRAKSRDI 1927
Score = 56.0 bits (129), Expect = 4e-07
Identities = 121/557 (21%), Positives = 234/557 (42%), Gaps = 74/557 (13%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q + + E LEL D T +E IIK K NL + + EH S+ E
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEHRSKAE----E 1265
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE 241
++ +L +Q +LS R E+ LI+ L R Q +E ++E
Sbjct: 1266 TQRSVNDLTSQRAKLQTENGELS-RQLDEKEALIS---QLTRGKLTYTQQLEDLKRQLEE 1321
Query: 242 IRELRSESENTKALEEMRHELD-------EERTAKLAIKEKLTTTESQLRQTRNRVA--- 291
E+++++ AL+ RH+ D EE AK ++ L+ S++ Q R +
Sbjct: 1322 --EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 292 ------------KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
K+ ++L+EAE ++ ++ LE + + ++E L ++
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE----DLMVDVERS 1435
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ---LEEDLKQTKRALQEQCEIT 396
+ L +++ + + E KQ+ E+ + +S+ ++ L +L + K A +E E
Sbjct: 1436 NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL 1495
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
+ + + E+ D + I ELEK + L E+ ++L + L+ + +L
Sbjct: 1496 ETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQ--LEAEK-MELQSALEEAEASLE 1552
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEE-------IIGKMQ--IQTRELIKNIK 507
E ++ + E ++ K I++KLA + E+ ++ +Q + +N
Sbjct: 1553 HEEGKILRAQLEF-NQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEA 1611
Query: 508 LNEQKVIQYEQYVRDLQ-AH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
L +K ++ + ++Q +H NR A Q+ + LQ + D +++L D V N++
Sbjct: 1612 LRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ-----VKSLQSLLKDTQIQLDDAVRANDD 1666
Query: 566 LSEILAKKDQ-------ELEQ------QDKNSRGQARVIKIR-EELINVLKNKETEQSRE 611
L E +A ++ ELE+ Q + SR A I E + +L ++ T +
Sbjct: 1667 LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ 1726
Query: 612 LAALQQDLEHRMRIVDE 628
+ DL V+E
Sbjct: 1727 KKKMDADLSQLQTEVEE 1743
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/296 (19%), Positives = 129/296 (43%), Gaps = 16/296 (5%)
Query: 136 ALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED 195
A E + +++++K + L + + + D+ E+++ + L L EL+ E
Sbjct: 1636 AAEAQKQVKSLQSLLKDTQIQLD-DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
Query: 196 AVNT--VTDLSKRACHERRTLI-AVGEALVREVAKLRQDVETRNVMIDE-IRELRSESEN 251
+ + + ER L+ + +L+ + K+ D+ ++E ++E R+ E
Sbjct: 1695 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEK 1754
Query: 252 TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA-SITSLTGT 310
K + EE + L + + QT + + +L EAE ++
Sbjct: 1755 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGKKQ 1811
Query: 311 VKMLEDQSRQKEVQLEARARKLRESLK---TGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
++ LE + R+ E +LEA ++ ES+K E +L Q + + +L + ++KL
Sbjct: 1812 LQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL 1871
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
++ K+ +Q EE +Q L + ++ E +ER + + + + +L+AK
Sbjct: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI----AESQVNKLRAK 1923
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 70.5 bits (165), Expect = 2e-11
Identities = 96/487 (19%), Positives = 217/487 (44%), Gaps = 61/487 (12%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALV---REVAKLRQDVETRNVMIDEIRELR 246
K + ++ + +L+ + E + + + + L + + +L++ + +N EI+ ++
Sbjct: 321 KEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN---QEIKNMK 377
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ--TRNRVAKMDKQLREAEASI 304
E N+K E E ++ + +K +SQ + + ++L + A +
Sbjct: 378 LELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAEL 437
Query: 305 TSLTGT--VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS---------- 352
+ G V+M ++ RQ Q+E + + ++ + S + D
Sbjct: 438 DEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINE 497
Query: 353 LQAEVLECKQQIEKLT------VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
L ++ + Q EKL ++ K A+Q+ EDL + +EQ + ++ I +E
Sbjct: 498 LNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESK 557
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E S + +E+L+A+I+ +S+ +L E E+ + K L + E E
Sbjct: 558 LNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNY------KIKLEMLEKEKNAVL 611
Query: 467 REKESENKIGIQQKLAAELL-NKEEIIGKMQ--IQTRELIKNIKLNEQKVIQYEQYVRDL 523
++ +E++ ++L +LL + EE + K++ ++ I KL + I Y+Q + L
Sbjct: 612 -DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGL 670
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
Q ++ Q+I ++ + +++ + +L ++K ++L+Q N
Sbjct: 671 Q------------------NEMSQKIETMQFEKDNLITKQNQLILEISKL-KDLQQSLVN 711
Query: 584 SRGQARVIKIRE--ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
S+ + ++I E + I +L+ +E E+ L+Q+++ + + KQ+ K +++Q
Sbjct: 712 SKSEEMTLQINELQKEIEILRQEEKEKG----TLEQEVQELQLKTELLEKQMKEKENDLQ 767
Query: 642 ELFATLE 648
E FA LE
Sbjct: 768 EKFAQLE 774
Score = 62.5 bits (145), Expect = 5e-09
Identities = 91/418 (21%), Positives = 187/418 (44%), Gaps = 31/418 (7%)
Query: 255 LEEMRHELDEER-TAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
+EE+ EL+E R T ++L E+ ++Q + ++ L++A
Sbjct: 171 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLE 230
Query: 314 LEDQSRQKEVQLEA--RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
L +QS++ ++Q + + LR S T T + L+Q + ++L +QQ+E+
Sbjct: 231 LTEQSQKLQIQFQQLQASETLRNS--THSSTAADLLQAKQ----QILTHQQQLEEQDHLL 284
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELK--ERTETELQDSRNAIEELQAKIIELEK 429
+ Q+ +ED LQE+ ++ + E + K + E+Q+ IEEL KIIE EK
Sbjct: 285 ED-YQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEK 343
Query: 430 S--KPNPDLPTEREI--DLWAELQATKETLRVTEDEVTTCK-REKESENKIGIQQKLAAE 484
+ L T ++ +L ++ + ++ + E+T K +E++S +I E
Sbjct: 344 KTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEE 403
Query: 485 LLNKEEIIGKMQ---IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
L + + + +Q E KL + + E Y + + + + Q
Sbjct: 404 LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIR-QHMAQMEE 462
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEIL--AKKDQELEQQDKNSRGQARVIKIREELIN 599
+ + M+ ++ + NE+ +++ A + ++ QD NS+ + K++EEL
Sbjct: 463 MKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE----KLKEELGL 518
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA---AKADEIQELFATLENKQQQI 654
+L+ K Q R+L L ++L + + IA +K +E + +T+E+ + +I
Sbjct: 519 ILEEKCALQ-RQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEI 575
Score = 53.2 bits (122), Expect = 3e-06
Identities = 100/442 (22%), Positives = 204/442 (46%), Gaps = 40/442 (9%)
Query: 181 ELCGALRELKTQAEDAV-NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMI 239
+L G L+E Q + N +L+ ER++ + + L+ V +L++ +
Sbjct: 357 KLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQ-LMGTVEELQKRNHKDSQFE 415
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTE-SQLRQTRNR-VAKMDKQ 296
+I + R E E + LE++R ELDE ++ +K++L +Q+ + + R +M+
Sbjct: 416 TDIVQ-RMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENA 474
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLE---ARARKLRESLKTGEVTTSQLIQQRDSL 353
LR + ++IT +K++ + ++L+ ++ KL+E L L +Q + L
Sbjct: 475 LR-SYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDL 533
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
E+ ++QI++ + I + E L + ++L E K EI + EL+
Sbjct: 534 VEELSFSREQIQRA----RQTIAEQESKLNEAHKSLST-VEDLKAEIVSASESRKELELK 588
Query: 414 RNA-IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT-EDEVTTCKREKES 471
A + + K+ LEK K N L E AEL+ + L + E+E++ K + E
Sbjct: 589 HEAEVTNYKIKLEMLEKEK-NAVLDRMAESQE-AELERLRTQLLFSHEEELSKLKEDLEI 646
Query: 472 ENKIGIQQ-KLAAELLNKEEIIG-----KMQIQTRELIKNIKLNEQKVIQYE-QYVRDLQ 524
E++I I++ K + K++I G +I+T + K+ + +Q + E ++DLQ
Sbjct: 647 EHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ 706
Query: 525 -------AHNRTIA-NCQESPNGISYQD------LQQEIMDLKMKLLDVVHRNEELSEIL 570
+ T+ N + I Q+ L+QE+ +L++K + + +E L
Sbjct: 707 QSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDL 766
Query: 571 AKKDQELEQQDKNSRGQARVIK 592
+K +LE ++ + + + ++
Sbjct: 767 QEKFAQLEAENSILKDEKKTLE 788
Score = 51.2 bits (117), Expect = 1e-05
Identities = 79/383 (20%), Positives = 166/383 (43%), Gaps = 24/383 (6%)
Query: 108 ILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKT--NLTVN-QDQT 164
+L +A+ E+ +L + S E L L E + IE+ I K NL ++ + Q
Sbjct: 610 VLDRMAESQEAELERLRTQLLFSH--EEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQI 667
Query: 165 DGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVG-EALVR 223
DG E + FE + + + Q ++ + DL + + + + + L +
Sbjct: 668 DGLQNEMSQKIETMQFEKDNLITK-QNQLILEISKLKDLQQSLVNSKSEEMTLQINELQK 726
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENT-KALEEMRHELDEE----RTAKLAIKEKLTT 278
E+ LRQ+ + + + E++EL+ ++E K ++E ++L E+ +K++ T
Sbjct: 727 EIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKT 786
Query: 279 TESQLR-----QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQS-RQKEVQLEARARKL 332
E L+ R+ +D +++ S+ + + E++ +Q+ +QL K
Sbjct: 787 LEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQ 846
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE----KLTVQHKSAIQQLEEDLKQTKRA 388
R + E Q+ A +L+ K +E K +++KS ++ L E+L +R
Sbjct: 847 RNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL-HLQRI 905
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE-LEKSKPNPDLPTEREIDLWAE 447
++ + + E + +E+ +++E LE +K ++R DL +
Sbjct: 906 NPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQ 965
Query: 448 LQATKETLRVTEDEVTTCKREKE 470
L+ + +EV + K+EKE
Sbjct: 966 LKQKHGEISFLNEEVKSLKQEKE 988
Score = 39.9 bits (89), Expect = 0.030
Identities = 78/419 (18%), Positives = 176/419 (42%), Gaps = 36/419 (8%)
Query: 263 DEERTAKL-AIKEKLTTTESQLRQTRNRV-AKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
DEER KL A K KL + Q+ + +K K+ R+ +S ++ + DQS+
Sbjct: 3 DEERQKKLEAGKAKLAQFRQRKAQSDGQSPSKKQKKKRKTSSSKHDVSAHHDLNIDQSQC 62
Query: 321 KEVQLEARAR---------KLRESLKTGEVTTSQL---IQQRDSLQAEVLECKQQIE--K 366
E+ + + R + +L +GE+T+ + ++ + +C ++
Sbjct: 63 NEMYINSSQRVESTVIPESTIMRTLHSGEITSHEQGFSVELESEISTTADDCSSEVNGCS 122
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQ-CEITKREIELKERTETELQDSRNAIEELQAKII 425
++ L E+ + EQ + + +E+ E +EL ++ IEEL ++
Sbjct: 123 FVMRTGKPTNLLREEEFGVDDSYSEQGAQDSPTHLEMME---SELAGKQHEIEELNRELE 179
Query: 426 ELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAEL 485
E+ + L +E + A ++ + + +REK+ + ++ ++
Sbjct: 180 EMRVTYGTEGLQQLQEFE--AAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQK 237
Query: 486 LNKEEIIGKMQIQTRELIKNIKLNEQK--VIQYEQYV----RDLQAHNRTIANCQESPNG 539
L I Q+Q E ++N + ++Q +Q + + L+ + + + Q+
Sbjct: 238 LQ----IQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKED 293
Query: 540 ISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ Q LQ++I +M+ D N EI K+ E K + + ++++++L
Sbjct: 294 FTMQISFLQEKIKVYEMEQ-DKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKL 352
Query: 598 INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
K Q + + Q+ ++ + + K+ ++EI++L T+E Q++ H+
Sbjct: 353 TTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE-RQSSEEIKQLMGTVEELQKRNHK 410
>AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein.
Length = 1642
Score = 70.5 bits (165), Expect = 2e-11
Identities = 96/487 (19%), Positives = 217/487 (44%), Gaps = 61/487 (12%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALV---REVAKLRQDVETRNVMIDEIRELR 246
K + ++ + +L+ + E + + + + L + + +L++ + +N EI+ ++
Sbjct: 333 KEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN---QEIKNMK 389
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ--TRNRVAKMDKQLREAEASI 304
E N+K E E ++ + +K +SQ + + ++L + A +
Sbjct: 390 LELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAEL 449
Query: 305 TSLTGT--VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS---------- 352
+ G V+M ++ RQ Q+E + + ++ + S + D
Sbjct: 450 DEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINE 509
Query: 353 LQAEVLECKQQIEKLT------VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
L ++ + Q EKL ++ K A+Q+ EDL + +EQ + ++ I +E
Sbjct: 510 LNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESK 569
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E S + +E+L+A+I+ +S+ +L E E+ + K L + E E
Sbjct: 570 LNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNY------KIKLEMLEKEKNAVL 623
Query: 467 REKESENKIGIQQKLAAELL-NKEEIIGKMQ--IQTRELIKNIKLNEQKVIQYEQYVRDL 523
++ +E++ ++L +LL + EE + K++ ++ I KL + I Y+Q + L
Sbjct: 624 -DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGL 682
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
Q ++ Q+I ++ + +++ + +L ++K ++L+Q N
Sbjct: 683 Q------------------NEMSQKIETMQFEKDNLITKQNQLILEISKL-KDLQQSLVN 723
Query: 584 SRGQARVIKIRE--ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
S+ + ++I E + I +L+ +E E+ L+Q+++ + + KQ+ K +++Q
Sbjct: 724 SKSEEMTLQINELQKEIEILRQEEKEKG----TLEQEVQELQLKTELLEKQMKEKENDLQ 779
Query: 642 ELFATLE 648
E FA LE
Sbjct: 780 EKFAQLE 786
Score = 62.5 bits (145), Expect = 5e-09
Identities = 91/418 (21%), Positives = 187/418 (44%), Gaps = 31/418 (7%)
Query: 255 LEEMRHELDEER-TAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
+EE+ EL+E R T ++L E+ ++Q + ++ L++A
Sbjct: 183 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLE 242
Query: 314 LEDQSRQKEVQLEA--RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
L +QS++ ++Q + + LR S T T + L+Q + ++L +QQ+E+
Sbjct: 243 LTEQSQKLQIQFQQLQASETLRNS--THSSTAADLLQAKQ----QILTHQQQLEEQDHLL 296
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELK--ERTETELQDSRNAIEELQAKIIELEK 429
+ Q+ +ED LQE+ ++ + E + K + E+Q+ IEEL KIIE EK
Sbjct: 297 ED-YQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEK 355
Query: 430 S--KPNPDLPTEREI--DLWAELQATKETLRVTEDEVTTCK-REKESENKIGIQQKLAAE 484
+ L T ++ +L ++ + ++ + E+T K +E++S +I E
Sbjct: 356 KTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEE 415
Query: 485 LLNKEEIIGKMQ---IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
L + + + +Q E KL + + E Y + + + + Q
Sbjct: 416 LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIR-QHMAQMEE 474
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEIL--AKKDQELEQQDKNSRGQARVIKIREELIN 599
+ + M+ ++ + NE+ +++ A + ++ QD NS+ + K++EEL
Sbjct: 475 MKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE----KLKEELGL 530
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA---AKADEIQELFATLENKQQQI 654
+L+ K Q R+L L ++L + + IA +K +E + +T+E+ + +I
Sbjct: 531 ILEEKCALQ-RQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEI 587
Score = 53.2 bits (122), Expect = 3e-06
Identities = 100/442 (22%), Positives = 204/442 (46%), Gaps = 40/442 (9%)
Query: 181 ELCGALRELKTQAEDAV-NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMI 239
+L G L+E Q + N +L+ ER++ + + L+ V +L++ +
Sbjct: 369 KLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQ-LMGTVEELQKRNHKDSQFE 427
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTE-SQLRQTRNR-VAKMDKQ 296
+I + R E E + LE++R ELDE ++ +K++L +Q+ + + R +M+
Sbjct: 428 TDIVQ-RMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENA 486
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLE---ARARKLRESLKTGEVTTSQLIQQRDSL 353
LR + ++IT +K++ + ++L+ ++ KL+E L L +Q + L
Sbjct: 487 LR-SYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDL 545
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
E+ ++QI++ + I + E L + ++L E K EI + EL+
Sbjct: 546 VEELSFSREQIQRA----RQTIAEQESKLNEAHKSLST-VEDLKAEIVSASESRKELELK 600
Query: 414 RNA-IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT-EDEVTTCKREKES 471
A + + K+ LEK K N L E AEL+ + L + E+E++ K + E
Sbjct: 601 HEAEVTNYKIKLEMLEKEK-NAVLDRMAESQE-AELERLRTQLLFSHEEELSKLKEDLEI 658
Query: 472 ENKIGIQQ-KLAAELLNKEEIIG-----KMQIQTRELIKNIKLNEQKVIQYE-QYVRDLQ 524
E++I I++ K + K++I G +I+T + K+ + +Q + E ++DLQ
Sbjct: 659 EHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ 718
Query: 525 -------AHNRTIA-NCQESPNGISYQD------LQQEIMDLKMKLLDVVHRNEELSEIL 570
+ T+ N + I Q+ L+QE+ +L++K + + +E L
Sbjct: 719 QSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDL 778
Query: 571 AKKDQELEQQDKNSRGQARVIK 592
+K +LE ++ + + + ++
Sbjct: 779 QEKFAQLEAENSILKDEKKTLE 800
Score = 48.4 bits (110), Expect = 9e-05
Identities = 79/383 (20%), Positives = 164/383 (42%), Gaps = 24/383 (6%)
Query: 108 ILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKT--NLTVN-QDQT 164
+L +A+ E+ +L + S E L L E + IE+ I K NL ++ + Q
Sbjct: 622 VLDRMAESQEAELERLRTQLLFSH--EEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQI 679
Query: 165 DGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVG-EALVR 223
DG E + FE + + + Q ++ + DL + + + + + L +
Sbjct: 680 DGLQNEMSQKIETMQFEKDNLITK-QNQLILEISKLKDLQQSLVNSKSEEMTLQINELQK 738
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENT-KALEEMRHELDEE----RTAKLAIKEKLTT 278
E+ LRQ+ + + + E++EL+ ++E K ++E ++L E+ +K++ T
Sbjct: 739 EIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKT 798
Query: 279 TESQLR-----QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQS-RQKEVQLEARARKL 332
E L+ R+ +D +++ S+ + + E++ +Q+ +QL K
Sbjct: 799 LEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQ 858
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE----KLTVQHKSAIQQLEEDLKQTKRA 388
R + E Q+ A +L+ K +E K +++KS ++ L E+L +R
Sbjct: 859 RNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL-HLQRI 917
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE-LEKSKPNPDLPTEREIDLWAE 447
++ + + E + E+ +++E LE +K ++R DL +
Sbjct: 918 NPTTVKMKSSVFDEDKTFVAETLEMGEVXEKDTTELMEKLEVTKREKLELSQRLSDLSEQ 977
Query: 448 LQATKETLRVTEDEVTTCKREKE 470
L+ + +EV + K EKE
Sbjct: 978 LKPKPGEISFLNEEVKSLKPEKE 1000
Score = 37.1 bits (82), Expect = 0.21
Identities = 74/432 (17%), Positives = 180/432 (41%), Gaps = 35/432 (8%)
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+ E K LE + +++E A L +++ + + + +K K+ R+ +S +
Sbjct: 3 DEERQKKLEAGKAKIEELSLAFL-VRQLAQFRQRKAQSDGQSPSKKQKKKRKTSSSKHDV 61
Query: 308 TGTVKMLEDQSRQKEVQLEARAR---------KLRESLKTGEVTTSQL---IQQRDSLQA 355
+ + DQS+ E+ + + R + +L +GE+T+ + ++ +
Sbjct: 62 SAHHDLNIDQSQCNEMYINSSQRVESTVIPESTIMRTLHSGEITSHEQGFSVELESEIST 121
Query: 356 EVLECKQQIE--KLTVQHKSAIQQLEEDLKQTKRALQEQ-CEITKREIELKERTETELQD 412
+C ++ ++ L E+ + EQ + + +E+ E +EL
Sbjct: 122 TADDCSSEVNGCSFVMRTGKPTNLLREEEFGVDDSYSEQGAQDSPTHLEMME---SELAG 178
Query: 413 SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
++ IEEL ++ E+ + L +E + A ++ + + +REK+
Sbjct: 179 KQHEIEELNRELEEMRVTYGTEGLQQLQEFE--AAIKQRDGIITQLTANLQQARREKDET 236
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQK--VIQYEQYV----RDLQAH 526
+ ++ ++ L I Q+Q E ++N + ++Q +Q + + L+
Sbjct: 237 MREFLELTEQSQKLQ----IQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQ 292
Query: 527 NRTIANCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNS 584
+ + + Q+ + Q LQ++I +M+ D N EI K+ E K
Sbjct: 293 DHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQ-DKKVENSNKEEIQEKETIIEELNTKII 351
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF 644
+ + ++++++L K Q + + Q+ ++ + + K+ ++EI++L
Sbjct: 352 EEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE-RQSSEEIKQLM 410
Query: 645 ATLENKQQQIHR 656
T+E Q++ H+
Sbjct: 411 GTVEELQKRNHK 422
>AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein.
Length = 1620
Score = 70.5 bits (165), Expect = 2e-11
Identities = 96/487 (19%), Positives = 217/487 (44%), Gaps = 61/487 (12%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALV---REVAKLRQDVETRNVMIDEIRELR 246
K + ++ + +L+ + E + + + + L + + +L++ + +N EI+ ++
Sbjct: 302 KEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN---QEIKNMK 358
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ--TRNRVAKMDKQLREAEASI 304
E N+K E E ++ + +K +SQ + + ++L + A +
Sbjct: 359 LELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAEL 418
Query: 305 TSLTGT--VKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS---------- 352
+ G V+M ++ RQ Q+E + + ++ + S + D
Sbjct: 419 DEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINE 478
Query: 353 LQAEVLECKQQIEKLT------VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERT 406
L ++ + Q EKL ++ K A+Q+ EDL + +EQ + ++ I +E
Sbjct: 479 LNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESK 538
Query: 407 ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCK 466
E S + +E+L+A+I+ +S+ +L E E+ + K L + E E
Sbjct: 539 LNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNY------KIKLEMLEKEKNAVL 592
Query: 467 REKESENKIGIQQKLAAELL-NKEEIIGKMQ--IQTRELIKNIKLNEQKVIQYEQYVRDL 523
++ +E++ ++L +LL + EE + K++ ++ I KL + I Y+Q + L
Sbjct: 593 -DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGL 651
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN 583
Q ++ Q+I ++ + +++ + +L ++K ++L+Q N
Sbjct: 652 Q------------------NEMSQKIETMQFEKDNLITKQNQLILEISKL-KDLQQSLVN 692
Query: 584 SRGQARVIKIRE--ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
S+ + ++I E + I +L+ +E E+ L+Q+++ + + KQ+ K +++Q
Sbjct: 693 SKSEEMTLQINELQKEIEILRQEEKEKG----TLEQEVQELQLKTELLEKQMKEKENDLQ 748
Query: 642 ELFATLE 648
E FA LE
Sbjct: 749 EKFAQLE 755
Score = 62.5 bits (145), Expect = 5e-09
Identities = 91/418 (21%), Positives = 187/418 (44%), Gaps = 31/418 (7%)
Query: 255 LEEMRHELDEER-TAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
+EE+ EL+E R T ++L E+ ++Q + ++ L++A
Sbjct: 152 IEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLE 211
Query: 314 LEDQSRQKEVQLEA--RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH 371
L +QS++ ++Q + + LR S T T + L+Q + ++L +QQ+E+
Sbjct: 212 LTEQSQKLQIQFQQLQASETLRNS--THSSTAADLLQAKQ----QILTHQQQLEEQDHLL 265
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELK--ERTETELQDSRNAIEELQAKIIELEK 429
+ Q+ +ED LQE+ ++ + E + K + E+Q+ IEEL KIIE EK
Sbjct: 266 ED-YQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEK 324
Query: 430 S--KPNPDLPTEREI--DLWAELQATKETLRVTEDEVTTCK-REKESENKIGIQQKLAAE 484
+ L T ++ +L ++ + ++ + E+T K +E++S +I E
Sbjct: 325 KTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEE 384
Query: 485 LLNKEEIIGKMQ---IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
L + + + +Q E KL + + E Y + + + + Q
Sbjct: 385 LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIR-QHMAQMEE 443
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEIL--AKKDQELEQQDKNSRGQARVIKIREELIN 599
+ + M+ ++ + NE+ +++ A + ++ QD NS+ + K++EEL
Sbjct: 444 MKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKE----KLKEELGL 499
Query: 600 VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA---AKADEIQELFATLENKQQQI 654
+L+ K Q R+L L ++L + + IA +K +E + +T+E+ + +I
Sbjct: 500 ILEEKCALQ-RQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEI 556
Score = 53.2 bits (122), Expect = 3e-06
Identities = 100/442 (22%), Positives = 204/442 (46%), Gaps = 40/442 (9%)
Query: 181 ELCGALRELKTQAEDAV-NTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMI 239
+L G L+E Q + N +L+ ER++ + + L+ V +L++ +
Sbjct: 338 KLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQ-LMGTVEELQKRNHKDSQFE 396
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLA-IKEKLTTTE-SQLRQTRNR-VAKMDKQ 296
+I + R E E + LE++R ELDE ++ +K++L +Q+ + + R +M+
Sbjct: 397 TDIVQ-RMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENA 455
Query: 297 LREAEASITSLTGTVKMLEDQSRQKEVQLE---ARARKLRESLKTGEVTTSQLIQQRDSL 353
LR + ++IT +K++ + ++L+ ++ KL+E L L +Q + L
Sbjct: 456 LR-SYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDL 514
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
E+ ++QI++ + I + E L + ++L E K EI + EL+
Sbjct: 515 VEELSFSREQIQRA----RQTIAEQESKLNEAHKSLST-VEDLKAEIVSASESRKELELK 569
Query: 414 RNA-IEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT-EDEVTTCKREKES 471
A + + K+ LEK K N L E AEL+ + L + E+E++ K + E
Sbjct: 570 HEAEVTNYKIKLEMLEKEK-NAVLDRMAESQE-AELERLRTQLLFSHEEELSKLKEDLEI 627
Query: 472 ENKIGIQQ-KLAAELLNKEEIIG-----KMQIQTRELIKNIKLNEQKVIQYE-QYVRDLQ 524
E++I I++ K + K++I G +I+T + K+ + +Q + E ++DLQ
Sbjct: 628 EHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ 687
Query: 525 -------AHNRTIA-NCQESPNGISYQD------LQQEIMDLKMKLLDVVHRNEELSEIL 570
+ T+ N + I Q+ L+QE+ +L++K + + +E L
Sbjct: 688 QSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDL 747
Query: 571 AKKDQELEQQDKNSRGQARVIK 592
+K +LE ++ + + + ++
Sbjct: 748 QEKFAQLEAENSILKDEKKTLE 769
Score = 36.7 bits (81), Expect = 0.28
Identities = 108/571 (18%), Positives = 240/571 (42%), Gaps = 37/571 (6%)
Query: 117 AQEVAQLYRDAIASSTPENALELLDETMPIENI-IKYP--KTNLTVNQDQTDGDILEHLS 173
+QE ++ D+I S + ++ E E + EN +K + N + + + E
Sbjct: 779 SQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNF 838
Query: 174 RYNDQGF-ELCGALRELKTQAEDAVNT--VTDLSK-RACHERRTLIAVGEALVREVAKLR 229
N Q E L ++K ED+ N + SK +A +E L + V+ + +
Sbjct: 839 EVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 898
Query: 230 QDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNR 289
+ +T + E E+ E K E+ +L+ + KL + ++L+ QL+Q
Sbjct: 899 DEDKT---FVAETLEMGEVVE--KDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGE 953
Query: 290 VAKMD---KQLREAEASITSLTGTVKMLEDQSRQKEVQ-LEARARKLRESLKT-----GE 340
++ ++ K L++ + ++ ++++ + +R + VQ + + L + + T E
Sbjct: 954 ISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAE 1013
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED-----LKQTKRALQEQCEI 395
+ S++ + ++E K E +TV +S +QL D K++ + E
Sbjct: 1014 GSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSEN 1073
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
K + EL ++E D R +E Q + L S + E + L + KE L
Sbjct: 1074 DKLQKELNV-LKSEQNDLRLQMEA-QRICLSLVYSTHVDQVREYMENEKDKALCSLKEEL 1131
Query: 456 RVTEDE-VTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI 514
++E + ++ + E + Q+ E +IGK+Q E V+
Sbjct: 1132 IFAQEEKIKELQKIHQLELQTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVL 1191
Query: 515 --QYEQYVR-DLQAHNRTIANCQESPN-GISYQDLQQEIMDLKMKLLDVVHR-NEELSEI 569
Y ++ ++ A ++ + S N QD + E+ D + + ++++ EE +++
Sbjct: 1192 GEYYTPALKCEVNAEDKENSGDYISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKL 1251
Query: 570 LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ-DLEHRMRIVDE 628
L + + + + + G ++ EE + + + ++ L+ D+ H+ ++
Sbjct: 1252 LVLQTRLSKIWGQQTDGMK--LEFGEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSL 1309
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ + +++QEL + + + QQQ+ E+
Sbjct: 1310 QDLEKTKLEEQVQELESLISSLQQQLKETEQ 1340
Score = 35.5 bits (78), Expect = 0.64
Identities = 88/449 (19%), Positives = 202/449 (44%), Gaps = 50/449 (11%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E+ E+ T +L EKL T+ + + R++ + +QL++ I+ L VK L+ + Q
Sbjct: 913 EVVEKDTTELM--EKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQ 970
Query: 321 KEV---QLEARARKLR-ESLKTGEVTTSQLI--------QQRDSLQAEVLECKQQIEKLT 368
+ +LE R E++++ + S L+ + + ++V + + K+
Sbjct: 971 VSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIM 1030
Query: 369 VQHKSAIQQLE--EDLKQTKRALQEQCEITKR-EIELKERTETE-LQDSRNAIEELQAKI 424
V+ K + + + E+ KQ + L +TK + + +E + LQ N ++ Q +
Sbjct: 1031 VEDKVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDL 1090
Query: 425 -IELEKSKPNPDLPTEREIDLWAELQATK--ETLRVTEDEVTTCKREKESE----NKIGI 477
+++E + L +D E + + L ++E+ + EK E +++ +
Sbjct: 1091 RLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFAQEEKIKELQKIHQLEL 1150
Query: 478 QQKLAAELLNKEE----IIGKMQIQTRELIKNIKLNEQKVI--QYEQYVR-DLQAHNRTI 530
Q E ++ + +IGK+Q E V+ Y ++ ++ A ++
Sbjct: 1151 QTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKEN 1210
Query: 531 ANCQESPN-GISYQDLQQEIMDLKMKLLDVVHR-NEELSEILAKKDQ------------E 576
+ S N QD + E+ D + + ++++ EE +++L + + +
Sbjct: 1211 SGDYISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMK 1270
Query: 577 LEQQDKN-SRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAA 635
LE ++N + + + I ++ N L++ + +L++L QDLE + ++ ++V + +
Sbjct: 1271 LEFGEENLPKEETEFLSIHSQMTN-LEDIDVNHKSKLSSL-QDLE-KTKLEEQVQELESL 1327
Query: 636 KADEIQELFATLENKQQQIHRLEKIVLAL 664
+ Q+L T +N + +IH L+K + A+
Sbjct: 1328 ISSLQQQLKETEQNYEAEIHCLQKRLQAV 1356
Score = 34.3 bits (75), Expect = 1.5
Identities = 49/261 (18%), Positives = 113/261 (43%), Gaps = 16/261 (6%)
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
E E+EL ++ IEEL ++ E+ + L +E + A ++ + +
Sbjct: 139 EMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFE--AAIKQRDGIITQLTANLQ 196
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQK--VIQYEQYV- 520
+REK+ + ++ ++ L I Q+Q E ++N + ++Q +Q +
Sbjct: 197 QARREKDETMREFLELTEQSQKLQ----IQFQQLQASETLRNSTHSSTAADLLQAKQQIL 252
Query: 521 ---RDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILAKKDQ 575
+ L+ + + + Q+ + Q LQ++I +M+ D N EI K+
Sbjct: 253 THQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQ-DKKVENSNKEEIQEKETI 311
Query: 576 ELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAA 635
E K + + ++++++L K Q + + Q+ ++ + + K+
Sbjct: 312 IEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE-RQ 370
Query: 636 KADEIQELFATLENKQQQIHR 656
++EI++L T+E Q++ H+
Sbjct: 371 SSEEIKQLMGTVEELQKRNHK 391
>U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein.
Length = 2363
Score = 70.1 bits (164), Expect = 2e-11
Identities = 87/405 (21%), Positives = 193/405 (47%), Gaps = 33/405 (8%)
Query: 241 EIRELRSESENTKALE-EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
EI E R E ++L R EL E +L ++ L +++ T +A+ ++ +++
Sbjct: 1208 EIAETRFEVAQVESLRYRQRVELLERELQEL--QDSLNAEREKVQVTAKTMAQHEELMKK 1265
Query: 300 AEASITSLTGTVKMLEDQSRQKEV---QLEARARKLRESLKTGEVTTSQLIQQRDSLQAE 356
E ++ + T KML ++ + E Q++A+ RKL + + ++L ++ LQAE
Sbjct: 1266 TE-TMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAE 1324
Query: 357 VLECKQQIEKLTVQHKSAI-QQLEEDLKQTKRALQEQCEITKREIELKE----------R 405
++ +++ +++ + QQ + D ++ ++ L E+ TKR +L E R
Sbjct: 1325 KKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIAR 1384
Query: 406 TETELQDSRNAIEELQAKI--IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
+ L +++N I+ L+ + + EK DL + ID+ +++ + ++ T
Sbjct: 1385 SNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDA-KIIDIQEKVKTITQVKKIGRRYKT 1443
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+ K ++K+ ++ + ++E+ + ++Q EL + + E K E V +L
Sbjct: 1444 QYEELKAQQDKV-METSAQSSGDHQEQHVSVQEMQ--ELKETLNQAETKSKSLESQVENL 1500
Query: 524 QAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD 581
Q +T++ + + Q LQ E+ L+ L D + E+L + + +K+++ +
Sbjct: 1501 Q---KTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAI 1557
Query: 582 KNSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
++ + A + ++++L +N+E +Q R A QQ E +RI
Sbjct: 1558 VAAKSKIAHLAGVKDQLTK--ENEELKQ-RNGALDQQKDELDVRI 1599
Score = 64.5 bits (150), Expect = 1e-09
Identities = 85/442 (19%), Positives = 196/442 (44%), Gaps = 31/442 (7%)
Query: 232 VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAK--LAIKEKLTTTESQLRQTRNR 289
+ T+ ++ + +E+ + + +E +RT K + KE + SQLRQT +
Sbjct: 888 LNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQ 947
Query: 290 VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
V + ++L+ + +++ V LE +S KE Q+ R K EV + +
Sbjct: 948 VNDLKERLKTSTSNVEQYQAMVTSLE-ESLNKEKQVTEEVR------KNIEVRLKESAEF 1000
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
+ L+ +++E +++ ++L + AI+ +E+ L + K+ L + E +R T
Sbjct: 1001 QTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLS---SVQNEVQEALQRASTA 1057
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREK 469
L + + A + Q E K ERE+ L A A E L+ +++V+ K
Sbjct: 1058 LSNEQQARRDCQ----EQAKIAVEAQNKYERELMLHA---ADVEALQAAKEQVS--KMAS 1108
Query: 470 ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL--QAHN 527
++ QK ++LL + + + ++ + + + + + + D + +
Sbjct: 1109 VRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSD 1168
Query: 528 RTIANCQESPNGISYQDLQQE--IMDLKMKLLDVVHRNEELSEILAKKDQ-ELEQQDKNS 584
+ +A+ +E G L +E + +++L + R +E++E + Q E + +
Sbjct: 1169 KVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRV 1228
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLE--HRMRIVDEVNKQIAAKADEIQE 642
R ++ ++ +N + K ++ +A ++ ++ M +V E NK + + + +++
Sbjct: 1229 ELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQ 1288
Query: 643 LFATLENKQQQIHRLEKIVLAL 664
L+ Q ++ +LE +L L
Sbjct: 1289 ---DLQQMQAKVRKLELDILPL 1307
Score = 56.4 bits (130), Expect = 3e-07
Identities = 108/565 (19%), Positives = 237/565 (41%), Gaps = 41/565 (7%)
Query: 146 IENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED---AVNTVTD 202
IE + + + L VN+ + + L + N+Q L +EL+ A+D A+ +
Sbjct: 57 IEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEKNKELEI-AQDRNIAIQSQFT 114
Query: 203 LSKRACH-ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+K E+R LI E L +E+ L +DV+ N E ES TK E++ +
Sbjct: 115 RTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLN-------EKLKESNTTKG--ELQLK 165
Query: 262 LDEERTAKLAIK--EKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR 319
LDE + + +++K EK E +L ++N + + + E ++LE +
Sbjct: 166 LDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCN 225
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE 379
+ + E +L E + + + L + + L ++ E K+Q + + + +
Sbjct: 226 LENKKEE--VSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNEL-NAH 282
Query: 380 EDLKQTKRALQEQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT 438
L ++ + E E+ E L+++ A + +Q ++E+E+SK +
Sbjct: 283 IKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEM 342
Query: 439 EREID-LWAELQATKETLRVTEDEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKM 495
+I L EL+ + L T+ + E+ K+ + E+
Sbjct: 343 LEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELY-NA 401
Query: 496 QIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
++T++ + KL +++ +Y ++ V++++A + +E Y+ Q+ + L +
Sbjct: 402 YVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQRE-----EYERAQKAVASLSV 456
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
KL + + L E K +++ ++++R +K + I VL E E++R
Sbjct: 457 KLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLL-MELEEARG--- 512
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL-XXXXXXXXX 673
H +R + + I++ ++ I + + N ++ + +++++AL
Sbjct: 513 -----NHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETRERE 567
Query: 674 XXXXXXXKIAALEHELAAGLNRKER 698
KI L+ +L + L E+
Sbjct: 568 EQETTSSKITELQLKLESALTELEQ 592
Score = 56.0 bits (129), Expect = 4e-07
Identities = 108/501 (21%), Positives = 214/501 (42%), Gaps = 57/501 (11%)
Query: 192 QAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESEN 251
Q E+ VN + + K + A+ +L + K +Q E I E+R L+ +E
Sbjct: 943 QTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNI-EVR-LKESAEF 1000
Query: 252 TKALEEMRHELDEERTAKLAIKEK-LTTTESQLRQTRNRVAKMDKQLREA-EASITSLTG 309
LE+ E+++E+ K + + + E QL + + ++ + +++EA + + T+L+
Sbjct: 1001 QTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSN 1060
Query: 310 TVKMLEDQSRQKEVQLEARARKLRE-SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
+ D Q ++ +EA+ + RE L +V Q +++ S A V +Q +E+ T
Sbjct: 1061 EQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASV---RQHLEETT 1117
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
+ +S + + + ++ +R L+++ E E+ L D IE+L K++
Sbjct: 1118 QKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQ---IEKLSDKVVASV 1174
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
K L + ++ Q E LR E + E ++ + ELL +
Sbjct: 1175 KEGVQGPLNVSLSEEGKSQEQIL-EILRFIRREKEIAETRFEVAQVESLRYRQRVELLER 1233
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN---RTIANCQESPNGISYQDL 545
E + ++Q + +++ + + Q+E+ ++ + N T +E + QDL
Sbjct: 1234 E--LQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLE-QDL 1290
Query: 546 QQ---EIMDLKMKLLDVVHRNEELSE---ILAKKDQELEQQDKN--SRGQARVIKIR--- 594
QQ ++ L++ +L + N ELSE +L + + LE+ K +R Q V + +
Sbjct: 1291 QQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPD 1350
Query: 595 -EELINVLKNKETEQSR-------------ELA--------------ALQQDLEHRMRIV 626
EE +L KE R E+A +L++DL
Sbjct: 1351 TEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEK 1410
Query: 627 DEVNKQIAAKADEIQELFATL 647
+ + K + AK +IQE T+
Sbjct: 1411 ETIQKDLDAKIIDIQEKVKTI 1431
Score = 47.6 bits (108), Expect = 1e-04
Identities = 103/509 (20%), Positives = 205/509 (40%), Gaps = 44/509 (8%)
Query: 170 EHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRT-LIAVGEALVREVAKL 228
E + N Q L R ++ Q +D + L R +I E +++
Sbjct: 470 EDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSS 529
Query: 229 RQDVETRNVMIDEIRELRSESENTK-ALEEM--RHELDEERTAKLAIKEKLTTTESQLRQ 285
+ + V I EL+ +++ AL E+ E +E+ T I E ES L +
Sbjct: 530 SEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTE 589
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE-VTTS 344
Q++ + SI ++L Q+ + L A + T + +TS
Sbjct: 590 LEQLRKSRQHQMQLVD-SIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTS 648
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
Q + V+E + IE K+A++QL+E + K+ E +I ++E +
Sbjct: 649 QTVST--PAPVPVIESTEAIEA-----KAALKQLQEIFENYKKEKAENEKIQNEQLEKLQ 701
Query: 405 RTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
T+L+ I +L E + N + L Q T + E +
Sbjct: 702 EQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIIN 761
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
T ++ N+ ++ AE L KE+ + K + ++L++Q+ E + +
Sbjct: 762 TMTQDLRGANEKLAVAEIRAENLKKEKEMLK--------LSEVRLSQQR----ESLLAEQ 809
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNE-ELSEILAKKDQELEQQDK 582
+ N + N Q + GI L++ + K +L + + E E+S + K + E+EQ+
Sbjct: 810 RGQNLLLTNLQ-TIQGI----LERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHT 864
Query: 583 NSRG-QARVIKIREEL---INV-LKNKE--TEQSRELAALQQDLEHRMRIVDEVNKQIAA 635
+R +++ + +L N+ L KE +E+A L++ L + V + Q
Sbjct: 865 LTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTG 924
Query: 636 KA-----DEIQELFATLENKQQQIHRLEK 659
K +++ +L + L ++Q++ L++
Sbjct: 925 KGQPSNKEDVDDLVSQLRQTEEQVNDLKE 953
Score = 46.4 bits (105), Expect = 3e-04
Identities = 44/201 (21%), Positives = 92/201 (45%), Gaps = 15/201 (7%)
Query: 203 LSKRACHERRTLIAVGEA--LVREVAKLRQDVETRNVMIDEIRE----LRSESENT-KAL 255
LS++ H +R E L E+A+ + +I ++E +R+E E K L
Sbjct: 1358 LSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDL 1417
Query: 256 EEMRHELDEERTAKLAIKE---KLTTTESQLRQTRNRVAKMDKQL----REAEASITSLT 308
+ ++ E+ +K+ + T +L+ +++V + Q +E S+ +
Sbjct: 1418 DAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQ 1477
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
+ L +Q+ K LE++ L+++L E L +Q LQ+E+ +Q ++ T
Sbjct: 1478 ELKETL-NQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT 1536
Query: 369 VQHKSAIQQLEEDLKQTKRAL 389
Q + QQ+ E ++T++A+
Sbjct: 1537 TQEEQLRQQITEKEEKTRKAI 1557
Score = 41.5 bits (93), Expect = 0.010
Identities = 70/337 (20%), Positives = 146/337 (43%), Gaps = 34/337 (10%)
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
++ L+ + + + +I+ L +H+ + E+ + ++ L E E + E
Sbjct: 22 QNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLE 81
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE-DEVTTCKR- 467
L+ N ++ L K ELE + +R I + ++ TKE L + D + T +R
Sbjct: 82 LEKLNNQLKALTEKNKELE-------IAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERL 134
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK---NIKLNEQKVIQYEQYVRD-- 522
+E E ++L +L G++Q++ EL ++K E+++ Q ++ +
Sbjct: 135 SQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQN 194
Query: 523 --LQAHNRT-----IANCQESPNGI-----SYQDLQQEIMDLKMKLLDVVHRNEEL---- 566
L +T +A +E N I + ++ ++E+ L+ ++ + NE L
Sbjct: 195 TWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHV 254
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETE---QSRELAALQQDLEHRM 623
++L K + EQQ + +L N+ K+ + +S EL ++L +
Sbjct: 255 EDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLL 314
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQ-QQIHRLEK 659
+ E NK I E+++ +E + ++I RLEK
Sbjct: 315 KEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEK 351
>M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.
Length = 2871
Score = 70.1 bits (164), Expect = 2e-11
Identities = 104/494 (21%), Positives = 223/494 (45%), Gaps = 49/494 (9%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSES 249
K +DA T+ D +K ER + E R+ + ++ + V D + S +
Sbjct: 1466 KQSLDDAAKTIQDKNKEI--ERLKQLIDKETNDRKCLE-DENARLQRVQYDLQKANSSAT 1522
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTG 309
E L+ EL R + ++ T + + + +N + ++ Q ++ E + L
Sbjct: 1523 ETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKR 1582
Query: 310 TVKMLEDQSRQKEVQLEARARKLRE-SLK----TGEVTTSQLIQQR--DSL--QAEVLEC 360
T + ++ E +LE R L+E ++K T ++ + ++++R D L Q +VL+
Sbjct: 1583 TASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDG 1642
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
+ EK Q + +++L +++ +R L ++ E K+ E + ++D ++ E
Sbjct: 1643 HLR-EKQRTQEE--LRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNES 1699
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ IE+E+ + + T+ + L EL+ LR+ D++ + E +S+ I
Sbjct: 1700 K---IEIERLQSLTENLTKEHLMLEEELR----NLRLEYDDLRRGRSEADSDKNATI--- 1749
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRD-LQAHNRTIANCQESPN 538
EL ++ +I ++ + LI +++ + + Q E++ + L+A NR QES N
Sbjct: 1750 --LELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNR----IQESKN 1803
Query: 539 GISYQDLQQEIMDLKMKLL-----------DVVHRNEELSEILAKKDQELE---QQDKNS 584
+ ++E + +K+K+L D ++R + E + Q LE QQ +N
Sbjct: 1804 QCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQND 1863
Query: 585 RGQARV-IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAK-ADEIQE 642
Q + +EE I ++++ + RE +L+ ++E + + ++ K D +E
Sbjct: 1864 LNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRE 1923
Query: 643 LFATLENKQQQIHR 656
+ LE ++ + R
Sbjct: 1924 TQSQLETERSRYQR 1937
Score = 64.9 bits (151), Expect = 9e-10
Identities = 114/576 (19%), Positives = 244/576 (42%), Gaps = 39/576 (6%)
Query: 105 QELILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQT 164
++L L N +E +L RDA + + +N + LD+ N+ KY +Q +
Sbjct: 1025 EDLKLKNTKIEVLEEELRLARDANSENCNKN--KFLDQ-----NLQKY---QAECSQFKA 1074
Query: 165 DGDILEHLSRYND-QGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR 223
LE L R + G L + Q ++ +T L+ E+R +V + +
Sbjct: 1075 KLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQ 1134
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
+ Q + R + + + ESE KA++E +E++ R + E++L
Sbjct: 1135 QKNDYDQLQKARQCEKENLGWQKLESE--KAIKEKEYEIERLRVLLQEEGTRKREYENEL 1192
Query: 284 RQTRNRVAKMDKQLR---EAEASITSLT-GTVKML-EDQSRQKEVQLEARARK---LRES 335
+ RN + LR E E +IT T + M ED S+ QL+ +R+ L++
Sbjct: 1193 AKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDE 1252
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECK-------QQIEKLTVQHKSAIQQLEEDLKQTKRA 388
+ + Q +QR + L+ K Q+ + L ++ K +QQ ED + K++
Sbjct: 1253 IVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQS 1312
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
L+E + + + + ER + E Q+ E + ++ ++ + + + + + E+
Sbjct: 1313 LEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFE--TEI 1370
Query: 449 QATKETLR--VTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
TK T+ + E T + +N + L+ E+ + + + R + ++I
Sbjct: 1371 NITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDI 1430
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL 566
+ + + Q + L+ R + + + Y +Q + D + D E L
Sbjct: 1431 QQQKATGSEVSQRKQQLEVELRQVTQ-MRTEESVRY---KQSLDDAAKTIQDKNKEIERL 1486
Query: 567 SEILAKKDQELE-QQDKNSRGQARVIKIREELINVLK--NKETEQSRELAALQQDLEHRM 623
+++ K+ + + +D+N+R Q +++ + + NK Q +EL L+ D E
Sbjct: 1487 KQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVS 1546
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ ++ I + ++EL + +++++RL++
Sbjct: 1547 QERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKR 1582
Score = 62.9 bits (146), Expect = 4e-09
Identities = 108/543 (19%), Positives = 237/543 (43%), Gaps = 51/543 (9%)
Query: 128 IASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALR 187
+ ++ E + L ++ NI K LT+ +++ + + L ++
Sbjct: 1351 VRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIK 1410
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS 247
LK + + + ++ T V + + +LRQ + R + +R +S
Sbjct: 1411 RLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE--ESVRYKQS 1468
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+ K +++ E+ ER +L KE T L R+ ++ L++A +S T
Sbjct: 1469 LDDAAKTIQDKNKEI--ERLKQLIDKE--TNDRKCLEDENARLQRVQYDLQKANSSATET 1524
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
+K+ E + + + E +++ ++K ++T Q + LQ + +E + K
Sbjct: 1525 INKLKVQEQELTRLRIDYERVSQE--RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKR 1582
Query: 368 TVQHKSAIQQ-LEEDLKQTKRALQEQC-EITK--REIE----LKERTETELQDSRNAIEE 419
T S ++ LEE+L+ +R+L+EQ +IT +++E +K+R+E +L+ R+ ++
Sbjct: 1583 TASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDG 1642
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
EK + +L L +E++A + L ++ V E K I+
Sbjct: 1643 HLR-----EKQRTQEELRR-----LSSEVEALRRQLLQEQESVKQAHLRNEHFQK-AIED 1691
Query: 480 KLAAELLNKEEI-IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
K + LN+ +I I ++Q T L K + E+++ DL+ R+ A+
Sbjct: 1692 K--SRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLR-RGRSEAD------ 1742
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
D I++L+ +L +R EL ++ +L+++ +N R + + K +++ +
Sbjct: 1743 ----SDKNATILELRSQLQISNNRTLELQGLI----NDLQRERENLRQE--IEKFQKQAL 1792
Query: 599 NVLKNKETEQSRELAALQQDLEH---RMRIVDEVNKQIAAKADEIQELFATLENKQQQIH 655
N+ E + + Q+ E +++++++ ++ DE+ +TLE + +
Sbjct: 1793 EA-SNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQ 1851
Query: 656 RLE 658
RLE
Sbjct: 1852 RLE 1854
Score = 56.4 bits (130), Expect = 3e-07
Identities = 108/507 (21%), Positives = 215/507 (42%), Gaps = 69/507 (13%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKAL------EEM---RHELDEE-RTAKLAI 272
+ + + ++E V++ E + E EN A EEM R++ + E K I
Sbjct: 1162 KAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTI 1221
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKE---VQLEARA 329
KE E + RN++ ++ ++ R+ + I L ++ +Q R+ E +Q +A
Sbjct: 1222 KEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACG 1281
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA-IQQLEEDLKQ-TKR 387
++ + + E+ Q++QQR A + ++ K T+Q K+ I++L+ + ++ KR
Sbjct: 1282 SEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAK-TIQDKNKEIERLKAEFQEEAKR 1340
Query: 388 ALQEQCEITKRE-------IELKERTETELQDSRNAIEEL-QAKIIELEKSKPNPDLPTE 439
+ + E++K I LK + ETE+ ++ I +L K + + D T
Sbjct: 1341 RWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTR 1400
Query: 440 REIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ-----QKLAAEL-----LNKE 489
L E++ K TL T + + + + + + G + Q+L EL + E
Sbjct: 1401 ENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE 1460
Query: 490 EIIGKMQ--------IQTR----ELIKNI---KLNEQKVIQYE----QYVR-DLQAHNRT 529
E + Q IQ + E +K + + N++K ++ E Q V+ DLQ N
Sbjct: 1461 ESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKAN-- 1518
Query: 530 IANCQESPNGISYQ---------DLQQEIMDLKMKLLDVVHRNEELSEILAKK---DQEL 577
++ E+ N + Q D ++ + +K D+ L E+ +K ++EL
Sbjct: 1519 -SSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEEL 1577
Query: 578 EQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKA 637
+ + + + K EE + ++ EQ+ ++ L Q LE + + +
Sbjct: 1578 NRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQR 1637
Query: 638 DEIQELFATLENKQQQIHRLEKIVLAL 664
D + + Q+++ RL V AL
Sbjct: 1638 DVLDGHLREKQRTQEELRRLSSEVEAL 1664
Score = 37.9 bits (84), Expect = 0.12
Identities = 42/230 (18%), Positives = 95/230 (41%), Gaps = 20/230 (8%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
++ L N++ EL G + +L+ + E+ + K+A + +
Sbjct: 1751 ELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQA-------LEASNRIQESKN 1803
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
+ Q V+ R ++ +I+ L + + LE+ + A+ +K++L E + +Q
Sbjct: 1804 QCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRL---ECEKQQI 1860
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+N + + Q E +I + ++S +++ L + +L+ +K E
Sbjct: 1861 QNDLNQWKTQYSRKEEAIRKIESE----REKSEREKNSLRSEIERLQAEIKRIEERC--- 1913
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
R L+ E + Q+E +++ I +L + + R Q +CE T
Sbjct: 1914 ---RRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWT 1960
>J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplakin
mRNA, 3' end. ).
Length = 1752
Score = 70.1 bits (164), Expect = 2e-11
Identities = 104/494 (21%), Positives = 223/494 (45%), Gaps = 49/494 (9%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSES 249
K +DA T+ D +K ER + E R+ + ++ + V D + S +
Sbjct: 347 KQSLDDAAKTIQDKNKEI--ERLKQLIDKETNDRKCLE-DENARLQRVQYDLQKANSSAT 403
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTG 309
E L+ EL R + ++ T + + + +N + ++ Q ++ E + L
Sbjct: 404 ETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKR 463
Query: 310 TVKMLEDQSRQKEVQLEARARKLRE-SLK----TGEVTTSQLIQQR--DSL--QAEVLEC 360
T + ++ E +LE R L+E ++K T ++ + ++++R D L Q +VL+
Sbjct: 464 TASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDG 523
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
+ EK Q + +++L +++ +R L ++ E K+ E + ++D ++ E
Sbjct: 524 HLR-EKQRTQEE--LRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNES 580
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ IE+E+ + + T+ + L EL+ LR+ D++ + E +S+ I
Sbjct: 581 K---IEIERLQSLTENLTKEHLMLEEELR----NLRLEYDDLRRGRSEADSDKNATI--- 630
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRD-LQAHNRTIANCQESPN 538
EL ++ +I ++ + LI +++ + + Q E++ + L+A NR QES N
Sbjct: 631 --LELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNR----IQESKN 684
Query: 539 GISYQDLQQEIMDLKMKLL-----------DVVHRNEELSEILAKKDQELE---QQDKNS 584
+ ++E + +K+K+L D ++R + E + Q LE QQ +N
Sbjct: 685 QCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQND 744
Query: 585 RGQARV-IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAK-ADEIQE 642
Q + +EE I ++++ + RE +L+ ++E + + ++ K D +E
Sbjct: 745 LNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRE 804
Query: 643 LFATLENKQQQIHR 656
+ LE ++ + R
Sbjct: 805 TQSQLETERSRYQR 818
Score = 64.1 bits (149), Expect = 2e-09
Identities = 83/430 (19%), Positives = 187/430 (43%), Gaps = 26/430 (6%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLR---EAEASITS 306
E+ KA++E +E++ R + E++L + RN + LR E E +IT
Sbjct: 40 ESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITK 99
Query: 307 LT-GTVKML-EDQSRQKEVQLEARARK---LRESLKTGEVTTSQLIQQRDSLQAEVLECK 361
T + M ED S+ QL+ +R+ L++ + + Q +QR + L+ K
Sbjct: 100 TTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQK 159
Query: 362 -------QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
Q+ + L ++ K +QQ ED + K++L+E + + + + ER + E Q+
Sbjct: 160 ACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEA 219
Query: 415 NAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR--VTEDEVTTCKREKESE 472
E + ++ ++ + + + + + E+ TK T+ + E T + +
Sbjct: 220 KRRWEYENELSKVRNNYDEEIISLKNQFE--TEINITKTTIHQLTMQKEEDTSGYRAQID 277
Query: 473 NKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIAN 532
N + L+ E+ + + + R + ++I+ + + Q + L+ R +
Sbjct: 278 NLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQ 337
Query: 533 CQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELE-QQDKNSRGQARVI 591
+ + Y +Q + D + D E L +++ K+ + + +D+N+R Q
Sbjct: 338 -MRTEESVRY---KQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQY 393
Query: 592 KIREELINVLK--NKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+++ + + NK Q +EL L+ D E + ++ I + ++EL +
Sbjct: 394 DLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQK 453
Query: 650 KQQQIHRLEK 659
+++++RL++
Sbjct: 454 VEEELNRLKR 463
Score = 62.9 bits (146), Expect = 4e-09
Identities = 108/543 (19%), Positives = 237/543 (43%), Gaps = 51/543 (9%)
Query: 128 IASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALR 187
+ ++ E + L ++ NI K LT+ +++ + + L ++
Sbjct: 232 VRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIK 291
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS 247
LK + + + ++ T V + + +LRQ + R + +R +S
Sbjct: 292 RLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE--ESVRYKQS 349
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+ K +++ E+ ER +L KE T L R+ ++ L++A +S T
Sbjct: 350 LDDAAKTIQDKNKEI--ERLKQLIDKE--TNDRKCLEDENARLQRVQYDLQKANSSATET 405
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
+K+ E + + + E +++ ++K ++T Q + LQ + +E + K
Sbjct: 406 INKLKVQEQELTRLRIDYERVSQE--RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKR 463
Query: 368 TVQHKSAIQQ-LEEDLKQTKRALQEQC-EITK--REIE----LKERTETELQDSRNAIEE 419
T S ++ LEE+L+ +R+L+EQ +IT +++E +K+R+E +L+ R+ ++
Sbjct: 464 TASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDG 523
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
EK + +L L +E++A + L ++ V E K I+
Sbjct: 524 HLR-----EKQRTQEELRR-----LSSEVEALRRQLLQEQESVKQAHLRNEHFQK-AIED 572
Query: 480 KLAAELLNKEEI-IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
K + LN+ +I I ++Q T L K + E+++ DL+ R+ A+
Sbjct: 573 K--SRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLR-RGRSEAD------ 623
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
D I++L+ +L +R EL ++ +L+++ +N R + + K +++ +
Sbjct: 624 ----SDKNATILELRSQLQISNNRTLELQGLI----NDLQRERENLRQE--IEKFQKQAL 673
Query: 599 NVLKNKETEQSRELAALQQDLEH---RMRIVDEVNKQIAAKADEIQELFATLENKQQQIH 655
N+ E + + Q+ E +++++++ ++ DE+ +TLE + +
Sbjct: 674 EA-SNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQ 732
Query: 656 RLE 658
RLE
Sbjct: 733 RLE 735
Score = 56.4 bits (130), Expect = 3e-07
Identities = 108/507 (21%), Positives = 215/507 (42%), Gaps = 69/507 (13%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKAL------EEM---RHELDEE-RTAKLAI 272
+ + + ++E V++ E + E EN A EEM R++ + E K I
Sbjct: 43 KAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTI 102
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKE---VQLEARA 329
KE E + RN++ ++ ++ R+ + I L ++ +Q R+ E +Q +A
Sbjct: 103 KEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACG 162
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA-IQQLEEDLKQ-TKR 387
++ + + E+ Q++QQR A + ++ K T+Q K+ I++L+ + ++ KR
Sbjct: 163 SEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAK-TIQDKNKEIERLKAEFQEEAKR 221
Query: 388 ALQEQCEITKRE-------IELKERTETELQDSRNAIEEL-QAKIIELEKSKPNPDLPTE 439
+ + E++K I LK + ETE+ ++ I +L K + + D T
Sbjct: 222 RWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTR 281
Query: 440 REIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ-----QKLAAEL-----LNKE 489
L E++ K TL T + + + + + + G + Q+L EL + E
Sbjct: 282 ENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE 341
Query: 490 EIIGKMQ--------IQTR----ELIKNI---KLNEQKVIQYE----QYVR-DLQAHNRT 529
E + Q IQ + E +K + + N++K ++ E Q V+ DLQ N
Sbjct: 342 ESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKAN-- 399
Query: 530 IANCQESPNGISYQ---------DLQQEIMDLKMKLLDVVHRNEELSEILAKK---DQEL 577
++ E+ N + Q D ++ + +K D+ L E+ +K ++EL
Sbjct: 400 -SSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEEL 458
Query: 578 EQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKA 637
+ + + + K EE + ++ EQ+ ++ L Q LE + + +
Sbjct: 459 NRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQR 518
Query: 638 DEIQELFATLENKQQQIHRLEKIVLAL 664
D + + Q+++ RL V AL
Sbjct: 519 DVLDGHLREKQRTQEELRRLSSEVEAL 545
Score = 37.9 bits (84), Expect = 0.12
Identities = 42/230 (18%), Positives = 95/230 (41%), Gaps = 20/230 (8%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
++ L N++ EL G + +L+ + E+ + K+A + +
Sbjct: 632 ELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQA-------LEASNRIQESKN 684
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
+ Q V+ R ++ +I+ L + + LE+ + A+ +K++L E + +Q
Sbjct: 685 QCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRL---ECEKQQI 741
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+N + + Q E +I + ++S +++ L + +L+ +K E
Sbjct: 742 QNDLNQWKTQYSRKEEAIRKIESE----REKSEREKNSLRSEIERLQAEIKRIEERC--- 794
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
R L+ E + Q+E +++ I +L + + R Q +CE T
Sbjct: 795 ---RRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWT 841
>BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 70.1 bits (164), Expect = 2e-11
Identities = 90/473 (19%), Positives = 190/473 (40%), Gaps = 35/473 (7%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE 248
L + DAV + KRA E + +A E L + +L V T + DE L SE
Sbjct: 165 LSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTT---LQDEKNSLVSE 221
Query: 249 SEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+E + L+++ D+ T + +K + QL Q + +++ + L
Sbjct: 222 NEMMNEKLDQLDGSFDDPNTV---VAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEEL 278
Query: 308 TGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
+++E Q R E+ L R L++ + T+ + A LE +I +
Sbjct: 279 EK--QLIEFQHRNDELTSLAEETRALKDEIDVLRATSDK---------ANKLESTVEIYR 327
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE 426
+Q + +++ + L++T + E++ T+L+ + +++L K+
Sbjct: 328 QKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSS 387
Query: 427 LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELL 486
K +R + L KE L D + KE+ ++ Q
Sbjct: 388 ESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTL------KETNEELRCSQV------ 435
Query: 487 NKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
+++ + + + +N+ V E ++R LQ N+ + QE ++LQ
Sbjct: 436 -QQDHLNQTDASATKSYENLAAEIMPVEYREVFIR-LQHENKMLRLQQEGSENERIEELQ 493
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+++ K+ ++ E + + Q++E K+ + Q K E + LK K
Sbjct: 494 EQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGS--KSEGESSSKLKQKLE 551
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+L + ++L+ + +++++ I +I EL A L+ K + + +E+
Sbjct: 552 AHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEE 604
Score = 57.6 bits (133), Expect = 1e-07
Identities = 66/313 (21%), Positives = 142/313 (45%), Gaps = 14/313 (4%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLT 277
E +++ R +ET + ++ +L SES+ L L+E+ A L KE+L
Sbjct: 358 EEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLI 417
Query: 278 TTESQLRQTRNRVAKMDKQ---LREAEASITSLTGTV--KMLEDQSRQKEVQLEARARKL 332
L++T + Q L + +AS T + +++ + R+ ++L+ + L
Sbjct: 418 EQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKML 477
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
R + E + +Q++ + + + ++L+ K I++L++ ++ +++LQEQ
Sbjct: 478 RLQQEGSENERIEELQEQLEQKHRKMNELETEQRLS---KERIRELQQQIEDLQKSLQEQ 534
Query: 393 CEITKREI--ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
++ E +LK++ E ++ EELQ K +E +P+ + ++ +L A LQ
Sbjct: 535 GSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQK 594
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
E ++ E+ + + K + KL + E ++ + Q+ +E I +E
Sbjct: 595 KDEDMKAMEERYKMYLEKARNVIKT-LDPKL--NPASAEIMLLRKQLAEKERRIEILESE 651
Query: 511 QKVIQYEQYVRDL 523
KV ++ Y L
Sbjct: 652 CKVAKFRDYEEKL 664
Score = 41.5 bits (93), Expect = 0.010
Identities = 87/365 (23%), Positives = 157/365 (43%), Gaps = 60/365 (16%)
Query: 351 DSLQAEVLECKQQI---EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTE 407
+S+Q V+ Q++ E L+ A+ +LE+ LK RAL+E E + EL++R E
Sbjct: 146 ESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLK---RALEELQEALAEKEELRQRCE 202
Query: 408 ------TELQDSRNAI----EELQAKIIELEKSKPNPD-----------LPTEREIDLWA 446
T LQD +N++ E + K+ +L+ S +P+ L E+ +
Sbjct: 203 ELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENF 262
Query: 447 ELQATKETLRV--------------TEDEVTTCKRE----KESENKIGIQQKLAAELLNK 488
L+A K+ RV DE+T+ E K+ + + A +L +
Sbjct: 263 RLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLEST 322
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH--NRTIANCQESPNGISYQDLQ 546
EI + +L K +K ++ + Y L+ A Q QDL
Sbjct: 323 VEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLH 382
Query: 547 QEIMDLKMK---LLDVVHRNEELSEILAK-KDQELEQQD--KNSRGQARVIKIREELINV 600
++ + L + R EE E L K K++ +EQ+D K + + R +++++ +N
Sbjct: 383 VKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQ 442
Query: 601 LKNKETEQSRELAALQQDLEHR---MRIVDEVN----KQIAAKADEIQELFATLENKQQQ 653
T+ LAA +E+R +R+ E +Q ++ + I+EL LE K ++
Sbjct: 443 TDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRK 502
Query: 654 IHRLE 658
++ LE
Sbjct: 503 MNELE 507
>AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 70.1 bits (164), Expect = 2e-11
Identities = 87/405 (21%), Positives = 193/405 (47%), Gaps = 33/405 (8%)
Query: 241 EIRELRSESENTKALE-EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
EI E R E ++L R EL E +L ++ L +++ T +A+ ++ +++
Sbjct: 1208 EIAETRFEVAQVESLRYRQRVELLERELQEL--QDSLNAEREKVQVTAKTMAQHEELMKK 1265
Query: 300 AEASITSLTGTVKMLEDQSRQKEV---QLEARARKLRESLKTGEVTTSQLIQQRDSLQAE 356
E ++ + T KML ++ + E Q++A+ RKL + + ++L ++ LQAE
Sbjct: 1266 TE-TMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAE 1324
Query: 357 VLECKQQIEKLTVQHKSAI-QQLEEDLKQTKRALQEQCEITKREIELKE----------R 405
++ +++ +++ + QQ + D ++ ++ L E+ TKR +L E R
Sbjct: 1325 KKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIAR 1384
Query: 406 TETELQDSRNAIEELQAKI--IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
+ L +++N I+ L+ + + EK DL + ID+ +++ + ++ T
Sbjct: 1385 SNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDA-KIIDIQEKVKTITQVKKIGRRYKT 1443
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+ K ++K+ ++ + ++E+ + ++Q EL + + E K E V +L
Sbjct: 1444 QYEELKAQQDKV-METSAQSSGDHQEQHVSVQEMQ--ELKETLNQAETKSKSLESQVENL 1500
Query: 524 QAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD 581
Q +T++ + + Q LQ E+ L+ L D + E+L + + +K+++ +
Sbjct: 1501 Q---KTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAI 1557
Query: 582 KNSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
++ + A + ++++L +N+E +Q R A QQ E +RI
Sbjct: 1558 VAAKSKIAHLAGVKDQLTK--ENEELKQ-RNGALDQQKDELDVRI 1599
Score = 65.3 bits (152), Expect = 7e-10
Identities = 85/442 (19%), Positives = 197/442 (44%), Gaps = 31/442 (7%)
Query: 232 VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAK--LAIKEKLTTTESQLRQTRNR 289
+ T+ ++ + +E+ + ++ +E +RT K + KE + SQLRQT +
Sbjct: 888 LNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQ 947
Query: 290 VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
V + ++L+ + +++ V LE +S KE Q+ R K EV + +
Sbjct: 948 VNDLKERLKTSTSNVEQYQAMVTSLE-ESLNKEKQVTEEVR------KNIEVRLKESAEF 1000
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
+ L+ +++E +++ ++L + AI+ +E+ L + K+ L + E +R T
Sbjct: 1001 QTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLS---SVQNEVQEALQRASTA 1057
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREK 469
L + + A + Q E K ERE+ L A A E L+ +++V+ K
Sbjct: 1058 LSNEQQARRDCQ----EQAKIAVEAQNKYERELMLHA---ADVEALQAAKEQVS--KMAS 1108
Query: 470 ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL--QAHN 527
++ QK ++LL + + + ++ + + + + + + D + +
Sbjct: 1109 VRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSD 1168
Query: 528 RTIANCQESPNGISYQDLQQE--IMDLKMKLLDVVHRNEELSEILAKKDQ-ELEQQDKNS 584
+ +A+ +E G L +E + +++L + R +E++E + Q E + +
Sbjct: 1169 KVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRV 1228
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLE--HRMRIVDEVNKQIAAKADEIQE 642
R ++ ++ +N + K ++ +A ++ ++ M +V E NK + + + +++
Sbjct: 1229 ELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQ 1288
Query: 643 LFATLENKQQQIHRLEKIVLAL 664
L+ Q ++ +LE +L L
Sbjct: 1289 ---DLQQMQAKVRKLELDILPL 1307
Score = 56.4 bits (130), Expect = 3e-07
Identities = 108/565 (19%), Positives = 237/565 (41%), Gaps = 41/565 (7%)
Query: 146 IENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED---AVNTVTD 202
IE + + + L VN+ + + L + N+Q L +EL+ A+D A+ +
Sbjct: 57 IEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEKNKELEI-AQDRNIAIQSQFT 114
Query: 203 LSKRACH-ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+K E+R LI E L +E+ L +DV+ N E ES TK E++ +
Sbjct: 115 RTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLN-------EKLKESNTTKG--ELQLK 165
Query: 262 LDEERTAKLAIK--EKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR 319
LDE + + +++K EK E +L ++N + + + E ++LE +
Sbjct: 166 LDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCN 225
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE 379
+ + E +L E + + + L + + L ++ E K+Q + + + +
Sbjct: 226 LENKKEE--VSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNEL-NAH 282
Query: 380 EDLKQTKRALQEQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT 438
L ++ + E E+ E L+++ A + +Q ++E+E+SK +
Sbjct: 283 IKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEM 342
Query: 439 EREID-LWAELQATKETLRVTEDEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKM 495
+I L EL+ + L T+ + E+ K+ + E+
Sbjct: 343 LEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELY-NA 401
Query: 496 QIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
++T++ + KL +++ +Y ++ V++++A + +E Y+ Q+ + L +
Sbjct: 402 YVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQRE-----EYERAQKAVASLSV 456
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
KL + + L E K +++ ++++R +K + I VL E E++R
Sbjct: 457 KLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLL-MELEEARG--- 512
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL-XXXXXXXXX 673
H +R + + I++ ++ I + + N ++ + +++++AL
Sbjct: 513 -----NHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETRERE 567
Query: 674 XXXXXXXKIAALEHELAAGLNRKER 698
KI L+ +L + L E+
Sbjct: 568 EQETTSSKITELQLKLESALTELEQ 592
Score = 56.0 bits (129), Expect = 4e-07
Identities = 108/501 (21%), Positives = 214/501 (42%), Gaps = 57/501 (11%)
Query: 192 QAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESEN 251
Q E+ VN + + K + A+ +L + K +Q E I E+R L+ +E
Sbjct: 943 QTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNI-EVR-LKESAEF 1000
Query: 252 TKALEEMRHELDEERTAKLAIKEK-LTTTESQLRQTRNRVAKMDKQLREA-EASITSLTG 309
LE+ E+++E+ K + + + E QL + + ++ + +++EA + + T+L+
Sbjct: 1001 QTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSN 1060
Query: 310 TVKMLEDQSRQKEVQLEARARKLRE-SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
+ D Q ++ +EA+ + RE L +V Q +++ S A V +Q +E+ T
Sbjct: 1061 EQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASV---RQHLEETT 1117
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
+ +S + + + ++ +R L+++ E E+ L D IE+L K++
Sbjct: 1118 QKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQ---IEKLSDKVVASV 1174
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
K L + ++ Q E LR E + E ++ + ELL +
Sbjct: 1175 KEGVQGPLNVSLSEEGKSQEQIL-EILRFIRREKEIAETRFEVAQVESLRYRQRVELLER 1233
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN---RTIANCQESPNGISYQDL 545
E + ++Q + +++ + + Q+E+ ++ + N T +E + QDL
Sbjct: 1234 E--LQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLE-QDL 1290
Query: 546 QQ---EIMDLKMKLLDVVHRNEELSE---ILAKKDQELEQQDKN--SRGQARVIKIR--- 594
QQ ++ L++ +L + N ELSE +L + + LE+ K +R Q V + +
Sbjct: 1291 QQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPD 1350
Query: 595 -EELINVLKNKETEQSR-------------ELA--------------ALQQDLEHRMRIV 626
EE +L KE R E+A +L++DL
Sbjct: 1351 TEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEK 1410
Query: 627 DEVNKQIAAKADEIQELFATL 647
+ + K + AK +IQE T+
Sbjct: 1411 ETIQKDLDAKIIDIQEKVKTI 1431
Score = 48.8 bits (111), Expect = 6e-05
Identities = 104/509 (20%), Positives = 205/509 (40%), Gaps = 44/509 (8%)
Query: 170 EHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRT-LIAVGEALVREVAKL 228
E + N Q L R ++ Q +D + L R +I E +++
Sbjct: 470 EDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSS 529
Query: 229 RQDVETRNVMIDEIRELRSESENTK-ALEEM--RHELDEERTAKLAIKEKLTTTESQLRQ 285
+ + V I EL+ +++ AL E+ E +E+ T I E ES L +
Sbjct: 530 SEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTE 589
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE-VTTS 344
Q++ + SI ++L Q+ + L A + T + +TS
Sbjct: 590 LEQLRKSRQHQMQLVD-SIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTS 648
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
Q + V+E + IE K+A++QL+E + K+ E +I ++E +
Sbjct: 649 QTVST--PAPVPVIESTEAIEA-----KAALKQLQEIFENYKKEKAENEKIQNEQLEKLQ 701
Query: 405 RTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
T+L+ I +L E + N + L Q T + E +
Sbjct: 702 EQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIIN 761
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
T ++ N+ ++ AE L KE+ + K + ++L++Q+ E + +
Sbjct: 762 TMTQDLRGANEKLAVAEVRAENLKKEKEMLK--------LSEVRLSQQR----ESLLAEQ 809
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNE-ELSEILAKKDQELEQQDK 582
+ N + N Q + GI L++ + K +L + + E E+S + K + E+EQ+
Sbjct: 810 RGQNLLLTNLQ-TIQGI----LERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHT 864
Query: 583 NSRG-QARVIKIREEL---INV-LKNKE--TEQSRELAALQQDLEHRMRIVDEVNKQIAA 635
+R +++ + +L N+ L KE +E+A L+Q L + V + Q
Sbjct: 865 LTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTG 924
Query: 636 KA-----DEIQELFATLENKQQQIHRLEK 659
K +++ +L + L ++Q++ L++
Sbjct: 925 KGQPSNKEDVDDLVSQLRQTEEQVNDLKE 953
Score = 46.4 bits (105), Expect = 3e-04
Identities = 44/201 (21%), Positives = 92/201 (45%), Gaps = 15/201 (7%)
Query: 203 LSKRACHERRTLIAVGEA--LVREVAKLRQDVETRNVMIDEIRE----LRSESENT-KAL 255
LS++ H +R E L E+A+ + +I ++E +R+E E K L
Sbjct: 1358 LSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDL 1417
Query: 256 EEMRHELDEERTAKLAIKE---KLTTTESQLRQTRNRVAKMDKQL----REAEASITSLT 308
+ ++ E+ +K+ + T +L+ +++V + Q +E S+ +
Sbjct: 1418 DAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQ 1477
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
+ L +Q+ K LE++ L+++L E L +Q LQ+E+ +Q ++ T
Sbjct: 1478 ELKETL-NQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT 1536
Query: 369 VQHKSAIQQLEEDLKQTKRAL 389
Q + QQ+ E ++T++A+
Sbjct: 1537 TQEEQLRQQITEKEEKTRKAI 1557
Score = 41.5 bits (93), Expect = 0.010
Identities = 70/337 (20%), Positives = 146/337 (43%), Gaps = 34/337 (10%)
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
++ L+ + + + +I+ L +H+ + E+ + ++ L E E + E
Sbjct: 22 QNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLE 81
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE-DEVTTCKR- 467
L+ N ++ L K ELE + +R I + ++ TKE L + D + T +R
Sbjct: 82 LEKLNNQLKALTEKNKELE-------IAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERL 134
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK---NIKLNEQKVIQYEQYVRD-- 522
+E E ++L +L G++Q++ EL ++K E+++ Q ++ +
Sbjct: 135 SQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQN 194
Query: 523 --LQAHNRT-----IANCQESPNGI-----SYQDLQQEIMDLKMKLLDVVHRNEEL---- 566
L +T +A +E N I + ++ ++E+ L+ ++ + NE L
Sbjct: 195 TWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHV 254
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETE---QSRELAALQQDLEHRM 623
++L K + EQQ + +L N+ K+ + +S EL ++L +
Sbjct: 255 EDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLL 314
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQ-QQIHRLEK 659
+ E NK I E+++ +E + ++I RLEK
Sbjct: 315 KEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEK 351
>AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 70.1 bits (164), Expect = 2e-11
Identities = 87/405 (21%), Positives = 193/405 (47%), Gaps = 33/405 (8%)
Query: 241 EIRELRSESENTKALE-EMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
EI E R E ++L R EL E +L ++ L +++ T +A+ ++ +++
Sbjct: 1208 EIAETRFEVAQVESLRYRQRVELLERELQEL--QDSLNAEREKVQVTAKTMAQHEELMKK 1265
Query: 300 AEASITSLTGTVKMLEDQSRQKEV---QLEARARKLRESLKTGEVTTSQLIQQRDSLQAE 356
E ++ + T KML ++ + E Q++A+ RKL + + ++L ++ LQAE
Sbjct: 1266 TE-TMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAE 1324
Query: 357 VLECKQQIEKLTVQHKSAI-QQLEEDLKQTKRALQEQCEITKREIELKE----------R 405
++ +++ +++ + QQ + D ++ ++ L E+ TKR +L E R
Sbjct: 1325 KKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIAR 1384
Query: 406 TETELQDSRNAIEELQAKI--IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
+ L +++N I+ L+ + + EK DL + ID+ +++ + ++ T
Sbjct: 1385 SNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDA-KIIDIQEKVKTITQVKKIGRRYKT 1443
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+ K ++K+ ++ + ++E+ + ++Q EL + + E K E V +L
Sbjct: 1444 QYEELKAQQDKV-METSAQSSGDHQEQHVSVQEMQ--ELKETLNQAETKSKSLESQVENL 1500
Query: 524 QAHNRTIANCQESPNGISYQ--DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD 581
Q +T++ + + Q LQ E+ L+ L D + E+L + + +K+++ +
Sbjct: 1501 Q---KTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAI 1557
Query: 582 KNSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
++ + A + ++++L +N+E +Q R A QQ E +RI
Sbjct: 1558 VAAKSKIAHLAGVKDQLTK--ENEELKQ-RNGALDQQKDELDVRI 1599
Score = 65.3 bits (152), Expect = 7e-10
Identities = 85/442 (19%), Positives = 197/442 (44%), Gaps = 31/442 (7%)
Query: 232 VETRNVMIDEIRELRSESENTKALEEMRHELDEERTAK--LAIKEKLTTTESQLRQTRNR 289
+ T+ ++ + +E+ + ++ +E +RT K + KE + SQLRQT +
Sbjct: 888 LNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQ 947
Query: 290 VAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQ 349
V + ++L+ + +++ V LE +S KE Q+ R K EV + +
Sbjct: 948 VNDLKERLKTSTSNVEQYQAMVTSLE-ESLNKEKQVTEEVR------KNIEVRLKESAEF 1000
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
+ L+ +++E +++ ++L + AI+ +E+ L + K+ L + E +R T
Sbjct: 1001 QTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLS---SVQNEVQEALQRASTA 1057
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREK 469
L + + A + Q E K ERE+ L A A E L+ +++V+ K
Sbjct: 1058 LSNEQQARRDCQ----EQAKIAVEAQNKYERELMLHA---ADVEALQAAKEQVS--KMAS 1108
Query: 470 ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL--QAHN 527
++ QK ++LL + + + ++ + + + + + + D + +
Sbjct: 1109 VRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSD 1168
Query: 528 RTIANCQESPNGISYQDLQQE--IMDLKMKLLDVVHRNEELSEILAKKDQ-ELEQQDKNS 584
+ +A+ +E G L +E + +++L + R +E++E + Q E + +
Sbjct: 1169 KVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRV 1228
Query: 585 RGQARVIKIREELINVLKNKETEQSRELAALQQDLE--HRMRIVDEVNKQIAAKADEIQE 642
R ++ ++ +N + K ++ +A ++ ++ M +V E NK + + + +++
Sbjct: 1229 ELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQ 1288
Query: 643 LFATLENKQQQIHRLEKIVLAL 664
L+ Q ++ +LE +L L
Sbjct: 1289 ---DLQQMQAKVRKLELDILPL 1307
Score = 56.4 bits (130), Expect = 3e-07
Identities = 108/565 (19%), Positives = 237/565 (41%), Gaps = 41/565 (7%)
Query: 146 IENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAED---AVNTVTD 202
IE + + + L VN+ + + L + N+Q L +EL+ A+D A+ +
Sbjct: 57 IEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEKNKELEI-AQDRNIAIQSQFT 114
Query: 203 LSKRACH-ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE 261
+K E+R LI E L +E+ L +DV+ N E ES TK E++ +
Sbjct: 115 RTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLN-------EKLKESNTTKG--ELQLK 165
Query: 262 LDEERTAKLAIK--EKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR 319
LDE + + +++K EK E +L ++N + + + E ++LE +
Sbjct: 166 LDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCN 225
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE 379
+ + E +L E + + + L + + L ++ E K+Q + + + +
Sbjct: 226 LENKKEE--VSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNEL-NAH 282
Query: 380 EDLKQTKRALQEQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT 438
L ++ + E E+ E L+++ A + +Q ++E+E+SK +
Sbjct: 283 IKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEM 342
Query: 439 EREID-LWAELQATKETLRVTEDEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKM 495
+I L EL+ + L T+ + E+ K+ + E+
Sbjct: 343 LEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELY-NA 401
Query: 496 QIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKM 554
++T++ + KL +++ +Y ++ V++++A + +E Y+ Q+ + L +
Sbjct: 402 YVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQRE-----EYERAQKAVASLSV 456
Query: 555 KLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAA 614
KL + + L E K +++ ++++R +K + I VL E E++R
Sbjct: 457 KLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLL-MELEEARG--- 512
Query: 615 LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL-XXXXXXXXX 673
H +R + + I++ ++ I + + N ++ + +++++AL
Sbjct: 513 -----NHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETRERE 567
Query: 674 XXXXXXXKIAALEHELAAGLNRKER 698
KI L+ +L + L E+
Sbjct: 568 EQETTSSKITELQLKLESALTELEQ 592
Score = 56.0 bits (129), Expect = 4e-07
Identities = 108/501 (21%), Positives = 214/501 (42%), Gaps = 57/501 (11%)
Query: 192 QAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESEN 251
Q E+ VN + + K + A+ +L + K +Q E I E+R L+ +E
Sbjct: 943 QTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNI-EVR-LKESAEF 1000
Query: 252 TKALEEMRHELDEERTAKLAIKEK-LTTTESQLRQTRNRVAKMDKQLREA-EASITSLTG 309
LE+ E+++E+ K + + + E QL + + ++ + +++EA + + T+L+
Sbjct: 1001 QTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSN 1060
Query: 310 TVKMLEDQSRQKEVQLEARARKLRE-SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
+ D Q ++ +EA+ + RE L +V Q +++ S A V +Q +E+ T
Sbjct: 1061 EQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASV---RQHLEETT 1117
Query: 369 VQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELE 428
+ +S + + + ++ +R L+++ E E+ L D IE+L K++
Sbjct: 1118 QKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQ---IEKLSDKVVASV 1174
Query: 429 KSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK 488
K L + ++ Q E LR E + E ++ + ELL +
Sbjct: 1175 KEGVQGPLNVSLSEEGKSQEQIL-EILRFIRREKEIAETRFEVAQVESLRYRQRVELLER 1233
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN---RTIANCQESPNGISYQDL 545
E + ++Q + +++ + + Q+E+ ++ + N T +E + QDL
Sbjct: 1234 E--LQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLE-QDL 1290
Query: 546 QQ---EIMDLKMKLLDVVHRNEELSE---ILAKKDQELEQQDKN--SRGQARVIKIR--- 594
QQ ++ L++ +L + N ELSE +L + + LE+ K +R Q V + +
Sbjct: 1291 QQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPD 1350
Query: 595 -EELINVLKNKETEQSR-------------ELA--------------ALQQDLEHRMRIV 626
EE +L KE R E+A +L++DL
Sbjct: 1351 TEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEK 1410
Query: 627 DEVNKQIAAKADEIQELFATL 647
+ + K + AK +IQE T+
Sbjct: 1411 ETIQKDLDAKIIDIQEKVKTI 1431
Score = 48.8 bits (111), Expect = 6e-05
Identities = 104/509 (20%), Positives = 205/509 (40%), Gaps = 44/509 (8%)
Query: 170 EHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRT-LIAVGEALVREVAKL 228
E + N Q L R ++ Q +D + L R +I E +++
Sbjct: 470 EDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSS 529
Query: 229 RQDVETRNVMIDEIRELRSESENTK-ALEEM--RHELDEERTAKLAIKEKLTTTESQLRQ 285
+ + V I EL+ +++ AL E+ E +E+ T I E ES L +
Sbjct: 530 SEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTE 589
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE-VTTS 344
Q++ + SI ++L Q+ + L A + T + +TS
Sbjct: 590 LEQLRKSRQHQMQLVD-SIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTS 648
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
Q + V+E + IE K+A++QL+E + K+ E +I ++E +
Sbjct: 649 QTVST--PAPVPVIESTEAIEA-----KAALKQLQEIFENYKKEKAENEKIQNEQLEKLQ 701
Query: 405 RTETELQDSRNAIE-ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
T+L+ I +L E + N + L Q T + E +
Sbjct: 702 EQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIIN 761
Query: 464 TCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
T ++ N+ ++ AE L KE+ + K + ++L++Q+ E + +
Sbjct: 762 TMTQDLRGANEKLAVAEVRAENLKKEKEMLK--------LSEVRLSQQR----ESLLAEQ 809
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNE-ELSEILAKKDQELEQQDK 582
+ N + N Q + GI L++ + K +L + + E E+S + K + E+EQ+
Sbjct: 810 RGQNLLLTNLQ-TIQGI----LERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHT 864
Query: 583 NSRG-QARVIKIREEL---INV-LKNKE--TEQSRELAALQQDLEHRMRIVDEVNKQIAA 635
+R +++ + +L N+ L KE +E+A L+Q L + V + Q
Sbjct: 865 LTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTG 924
Query: 636 KA-----DEIQELFATLENKQQQIHRLEK 659
K +++ +L + L ++Q++ L++
Sbjct: 925 KGQPSNKEDVDDLVSQLRQTEEQVNDLKE 953
Score = 46.4 bits (105), Expect = 3e-04
Identities = 44/201 (21%), Positives = 92/201 (45%), Gaps = 15/201 (7%)
Query: 203 LSKRACHERRTLIAVGEA--LVREVAKLRQDVETRNVMIDEIRE----LRSESENT-KAL 255
LS++ H +R E L E+A+ + +I ++E +R+E E K L
Sbjct: 1358 LSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDL 1417
Query: 256 EEMRHELDEERTAKLAIKE---KLTTTESQLRQTRNRVAKMDKQL----REAEASITSLT 308
+ ++ E+ +K+ + T +L+ +++V + Q +E S+ +
Sbjct: 1418 DAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQ 1477
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
+ L +Q+ K LE++ L+++L E L +Q LQ+E+ +Q ++ T
Sbjct: 1478 ELKETL-NQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT 1536
Query: 369 VQHKSAIQQLEEDLKQTKRAL 389
Q + QQ+ E ++T++A+
Sbjct: 1537 TQEEQLRQQITEKEEKTRKAI 1557
Score = 41.5 bits (93), Expect = 0.010
Identities = 70/337 (20%), Positives = 146/337 (43%), Gaps = 34/337 (10%)
Query: 350 RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETE 409
++ L+ + + + +I+ L +H+ + E+ + ++ L E E + E
Sbjct: 22 QNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLE 81
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTE-DEVTTCKR- 467
L+ N ++ L K ELE + +R I + ++ TKE L + D + T +R
Sbjct: 82 LEKLNNQLKALTEKNKELE-------IAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERL 134
Query: 468 EKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIK---NIKLNEQKVIQYEQYVRD-- 522
+E E ++L +L G++Q++ EL ++K E+++ Q ++ +
Sbjct: 135 SQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQN 194
Query: 523 --LQAHNRT-----IANCQESPNGI-----SYQDLQQEIMDLKMKLLDVVHRNEEL---- 566
L +T +A +E N I + ++ ++E+ L+ ++ + NE L
Sbjct: 195 TWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHV 254
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETE---QSRELAALQQDLEHRM 623
++L K + EQQ + +L N+ K+ + +S EL ++L +
Sbjct: 255 EDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLL 314
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQ-QQIHRLEK 659
+ E NK I E+++ +E + ++I RLEK
Sbjct: 315 KEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEK 351
>AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 70.1 bits (164), Expect = 2e-11
Identities = 90/473 (19%), Positives = 190/473 (40%), Gaps = 35/473 (7%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE 248
L + DAV + KRA E + +A E L + +L V T + DE L SE
Sbjct: 165 LSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTT---LQDEKNSLVSE 221
Query: 249 SEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+E + L+++ D+ T + +K + QL Q + +++ + L
Sbjct: 222 NEMMNEKLDQLDGSFDDPNTV---VAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEEL 278
Query: 308 TGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
+++E Q R E+ L R L++ + T+ + A LE +I +
Sbjct: 279 EK--QLIEFQHRNDELTSLAEETRALKDEIDVLRATSDK---------ANKLESTVEIYR 327
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE 426
+Q + +++ + L++T + E++ T+L+ + +++L K+
Sbjct: 328 QKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSS 387
Query: 427 LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELL 486
K +R + L KE L D + KE+ ++ Q
Sbjct: 388 ESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTL------KETNEELRCSQV------ 435
Query: 487 NKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
+++ + + + +N+ V E ++R LQ N+ + QE ++LQ
Sbjct: 436 -QQDHLNQTDASATKSYENLAAEIMPVEYREVFIR-LQHENKMLRLQQEGSENERIEELQ 493
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+++ K+ ++ E + + Q++E K+ + Q K E + LK K
Sbjct: 494 EQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGS--KSEGESSSKLKQKLE 551
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+L + ++L+ + +++++ I +I EL A L+ K + + +E+
Sbjct: 552 AHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEE 604
Score = 57.6 bits (133), Expect = 1e-07
Identities = 66/313 (21%), Positives = 142/313 (45%), Gaps = 14/313 (4%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLT 277
E +++ R +ET + ++ +L SES+ L L+E+ A L KE+L
Sbjct: 358 EEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLI 417
Query: 278 TTESQLRQTRNRVAKMDKQ---LREAEASITSLTGTV--KMLEDQSRQKEVQLEARARKL 332
L++T + Q L + +AS T + +++ + R+ ++L+ + L
Sbjct: 418 EQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKML 477
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
R + E + +Q++ + + + ++L+ K I++L++ ++ +++LQEQ
Sbjct: 478 RLQQEGSENERIEELQEQLEQKHRKMNELETEQRLS---KERIRELQQQIEDLQKSLQEQ 534
Query: 393 CEITKREI--ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
++ E +LK++ E ++ EELQ K +E +P+ + ++ +L A LQ
Sbjct: 535 GSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQK 594
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
E ++ E+ + + K + KL + E ++ + Q+ +E I +E
Sbjct: 595 KDEDMKAMEERYKMYLEKARNVIKT-LDPKL--NPASAEIMLLRKQLAEKERRIEILESE 651
Query: 511 QKVIQYEQYVRDL 523
KV ++ Y L
Sbjct: 652 CKVAKFRDYEEKL 664
Score = 41.5 bits (93), Expect = 0.010
Identities = 87/365 (23%), Positives = 157/365 (43%), Gaps = 60/365 (16%)
Query: 351 DSLQAEVLECKQQI---EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTE 407
+S+Q V+ Q++ E L+ A+ +LE+ LK RAL+E E + EL++R E
Sbjct: 146 ESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLK---RALEELQEALAEKEELRQRCE 202
Query: 408 ------TELQDSRNAI----EELQAKIIELEKSKPNPD-----------LPTEREIDLWA 446
T LQD +N++ E + K+ +L+ S +P+ L E+ +
Sbjct: 203 ELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENF 262
Query: 447 ELQATKETLRV--------------TEDEVTTCKRE----KESENKIGIQQKLAAELLNK 488
L+A K+ RV DE+T+ E K+ + + A +L +
Sbjct: 263 RLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLEST 322
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH--NRTIANCQESPNGISYQDLQ 546
EI + +L K +K ++ + Y L+ A Q QDL
Sbjct: 323 VEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLH 382
Query: 547 QEIMDLKMK---LLDVVHRNEELSEILAK-KDQELEQQD--KNSRGQARVIKIREELINV 600
++ + L + R EE E L K K++ +EQ+D K + + R +++++ +N
Sbjct: 383 VKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQ 442
Query: 601 LKNKETEQSRELAALQQDLEHR---MRIVDEVN----KQIAAKADEIQELFATLENKQQQ 653
T+ LAA +E+R +R+ E +Q ++ + I+EL LE K ++
Sbjct: 443 TDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRK 502
Query: 654 IHRLE 658
++ LE
Sbjct: 503 MNELE 507
>AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.
Length = 2871
Score = 70.1 bits (164), Expect = 2e-11
Identities = 104/494 (21%), Positives = 223/494 (45%), Gaps = 49/494 (9%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSES 249
K +DA T+ D +K ER + E R+ + ++ + V D + S +
Sbjct: 1466 KQSLDDAAKTIQDKNKEI--ERLKQLIDKETNDRKCLE-DENARLQRVQYDLQKANSSAT 1522
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTG 309
E L+ EL R + ++ T + + + +N + ++ Q ++ E + L
Sbjct: 1523 ETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKR 1582
Query: 310 TVKMLEDQSRQKEVQLEARARKLRE-SLK----TGEVTTSQLIQQR--DSL--QAEVLEC 360
T + ++ E +LE R L+E ++K T ++ + ++++R D L Q +VL+
Sbjct: 1583 TASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDG 1642
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
+ EK Q + +++L +++ +R L ++ E K+ E + ++D ++ E
Sbjct: 1643 HLR-EKQRTQEE--LRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNES 1699
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+ IE+E+ + + T+ + L EL+ LR+ D++ + E +S+ I
Sbjct: 1700 K---IEIERLQSLTENLTKEHLMLEEELR----NLRLEYDDLRRGRSEADSDKNATI--- 1749
Query: 481 LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRD-LQAHNRTIANCQESPN 538
EL ++ +I ++ + LI +++ + + Q E++ + L+A NR QES N
Sbjct: 1750 --LELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNR----IQESKN 1803
Query: 539 GISYQDLQQEIMDLKMKLL-----------DVVHRNEELSEILAKKDQELE---QQDKNS 584
+ ++E + +K+K+L D ++R + E + Q LE QQ +N
Sbjct: 1804 QCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQND 1863
Query: 585 RGQARV-IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAK-ADEIQE 642
Q + +EE I ++++ + RE +L+ ++E + + ++ K D +E
Sbjct: 1864 LNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRE 1923
Query: 643 LFATLENKQQQIHR 656
+ LE ++ + R
Sbjct: 1924 TQSQLETERSRYQR 1937
Score = 64.9 bits (151), Expect = 9e-10
Identities = 114/576 (19%), Positives = 244/576 (42%), Gaps = 39/576 (6%)
Query: 105 QELILFNVADWTAQEVAQLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQT 164
++L L N +E +L RDA + + +N + LD+ N+ KY +Q +
Sbjct: 1025 EDLKLKNTKIEVLEEELRLARDANSENCNKN--KFLDQ-----NLQKY---QAECSQFKA 1074
Query: 165 DGDILEHLSRYND-QGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVR 223
LE L R + G L + Q ++ +T L+ E+R +V + +
Sbjct: 1075 KLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQ 1134
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQL 283
+ Q + R + + + ESE KA++E +E++ R + E++L
Sbjct: 1135 QKNDYDQLQKARQCEKENLGWQKLESE--KAIKEKEYEIERLRVLLQEEGTRKREYENEL 1192
Query: 284 RQTRNRVAKMDKQLR---EAEASITSLT-GTVKML-EDQSRQKEVQLEARARK---LRES 335
+ RN + LR E E +IT T + M ED S+ QL+ +R+ L++
Sbjct: 1193 AKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDE 1252
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECK-------QQIEKLTVQHKSAIQQLEEDLKQTKRA 388
+ + Q +QR + L+ K Q+ + L ++ K +QQ ED + K++
Sbjct: 1253 IVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQS 1312
Query: 389 LQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
L+E + + + + ER + E Q+ E + ++ ++ + + + + + E+
Sbjct: 1313 LEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFE--TEI 1370
Query: 449 QATKETLR--VTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
TK T+ + E T + +N + L+ E+ + + + R + ++I
Sbjct: 1371 NITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDI 1430
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL 566
+ + + Q + L+ R + + + Y +Q + D + D E L
Sbjct: 1431 QQQKATGSEVSQRKQQLEVELRQVTQ-MRTEESVRY---KQSLDDAAKTIQDKNKEIERL 1486
Query: 567 SEILAKKDQELE-QQDKNSRGQARVIKIREELINVLK--NKETEQSRELAALQQDLEHRM 623
+++ K+ + + +D+N+R Q +++ + + NK Q +EL L+ D E
Sbjct: 1487 KQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVS 1546
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ ++ I + ++EL + +++++RL++
Sbjct: 1547 QERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKR 1582
Score = 62.9 bits (146), Expect = 4e-09
Identities = 108/543 (19%), Positives = 237/543 (43%), Gaps = 51/543 (9%)
Query: 128 IASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALR 187
+ ++ E + L ++ NI K LT+ +++ + + L ++
Sbjct: 1351 VRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIK 1410
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS 247
LK + + + ++ T V + + +LRQ + R + +R +S
Sbjct: 1411 RLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE--ESVRYKQS 1468
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+ K +++ E+ ER +L KE T L R+ ++ L++A +S T
Sbjct: 1469 LDDAAKTIQDKNKEI--ERLKQLIDKE--TNDRKCLEDENARLQRVQYDLQKANSSATET 1524
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
+K+ E + + + E +++ ++K ++T Q + LQ + +E + K
Sbjct: 1525 INKLKVQEQELTRLRIDYERVSQE--RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKR 1582
Query: 368 TVQHKSAIQQ-LEEDLKQTKRALQEQC-EITK--REIE----LKERTETELQDSRNAIEE 419
T S ++ LEE+L+ +R+L+EQ +IT +++E +K+R+E +L+ R+ ++
Sbjct: 1583 TASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDG 1642
Query: 420 LQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQ 479
EK + +L L +E++A + L ++ V E K I+
Sbjct: 1643 HLR-----EKQRTQEELRR-----LSSEVEALRRQLLQEQESVKQAHLRNEHFQK-AIED 1691
Query: 480 KLAAELLNKEEI-IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
K + LN+ +I I ++Q T L K + E+++ DL+ R+ A+
Sbjct: 1692 K--SRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLR-RGRSEAD------ 1742
Query: 539 GISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI 598
D I++L+ +L +R EL ++ +L+++ +N R + + K +++ +
Sbjct: 1743 ----SDKNATILELRSQLQISNNRTLELQGLI----NDLQRERENLRQE--IEKFQKQAL 1792
Query: 599 NVLKNKETEQSRELAALQQDLEH---RMRIVDEVNKQIAAKADEIQELFATLENKQQQIH 655
N+ E + + Q+ E +++++++ ++ DE+ +TLE + +
Sbjct: 1793 EA-SNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQ 1851
Query: 656 RLE 658
RLE
Sbjct: 1852 RLE 1854
Score = 56.4 bits (130), Expect = 3e-07
Identities = 108/507 (21%), Positives = 215/507 (42%), Gaps = 69/507 (13%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKAL------EEM---RHELDEE-RTAKLAI 272
+ + + ++E V++ E + E EN A EEM R++ + E K I
Sbjct: 1162 KAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTI 1221
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKE---VQLEARA 329
KE E + RN++ ++ ++ R+ + I L ++ +Q R+ E +Q +A
Sbjct: 1222 KEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACG 1281
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA-IQQLEEDLKQ-TKR 387
++ + + E+ Q++QQR A + ++ K T+Q K+ I++L+ + ++ KR
Sbjct: 1282 SEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAK-TIQDKNKEIERLKAEFQEEAKR 1340
Query: 388 ALQEQCEITKRE-------IELKERTETELQDSRNAIEEL-QAKIIELEKSKPNPDLPTE 439
+ + E++K I LK + ETE+ ++ I +L K + + D T
Sbjct: 1341 RWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTR 1400
Query: 440 REIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ-----QKLAAEL-----LNKE 489
L E++ K TL T + + + + + + G + Q+L EL + E
Sbjct: 1401 ENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTE 1460
Query: 490 EIIGKMQ--------IQTR----ELIKNI---KLNEQKVIQYE----QYVR-DLQAHNRT 529
E + Q IQ + E +K + + N++K ++ E Q V+ DLQ N
Sbjct: 1461 ESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKAN-- 1518
Query: 530 IANCQESPNGISYQ---------DLQQEIMDLKMKLLDVVHRNEELSEILAKK---DQEL 577
++ E+ N + Q D ++ + +K D+ L E+ +K ++EL
Sbjct: 1519 -SSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEEL 1577
Query: 578 EQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKA 637
+ + + + K EE + ++ EQ+ ++ L Q LE + + +
Sbjct: 1578 NRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQR 1637
Query: 638 DEIQELFATLENKQQQIHRLEKIVLAL 664
D + + Q+++ RL V AL
Sbjct: 1638 DVLDGHLREKQRTQEELRRLSSEVEAL 1664
Score = 37.9 bits (84), Expect = 0.12
Identities = 42/230 (18%), Positives = 95/230 (41%), Gaps = 20/230 (8%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
++ L N++ EL G + +L+ + E+ + K+A + +
Sbjct: 1751 ELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQA-------LEASNRIQESKN 1803
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
+ Q V+ R ++ +I+ L + + LE+ + A+ +K++L E + +Q
Sbjct: 1804 QCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRL---ECEKQQI 1860
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+N + + Q E +I + ++S +++ L + +L+ +K E
Sbjct: 1861 QNDLNQWKTQYSRKEEAIRKIESE----REKSEREKNSLRSEIERLQAEIKRIEERC--- 1913
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
R L+ E + Q+E +++ I +L + + R Q +CE T
Sbjct: 1914 ---RRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWT 1960
>AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein.
Length = 728
Score = 70.1 bits (164), Expect = 2e-11
Identities = 90/473 (19%), Positives = 190/473 (40%), Gaps = 35/473 (7%)
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE 248
L + DAV + KRA E + +A E L + +L V T + DE L SE
Sbjct: 165 LSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTT---LQDEKNSLVSE 221
Query: 249 SEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+E + L+++ D+ T + +K + QL Q + +++ + L
Sbjct: 222 NEMMNEKLDQLDGSFDDPNTV---VAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEEL 278
Query: 308 TGTVKMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
+++E Q R E+ L R L++ + T+ + A LE +I +
Sbjct: 279 EK--QLIEFQHRNDELTSLAEETRALKDEIDVLRATSDK---------ANKLESTVEIYR 327
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE 426
+Q + +++ + L++T + E++ T+L+ + +++L K+
Sbjct: 328 QKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSS 387
Query: 427 LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELL 486
K +R + L KE L D + KE+ ++ Q
Sbjct: 388 ESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTL------KETNEELRCSQV------ 435
Query: 487 NKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
+++ + + + +N+ V E ++R LQ N+ + QE ++LQ
Sbjct: 436 -QQDHLNQTDASATKSYENLAAEIMPVEYREVFIR-LQHENKMLRLQQEGSENERIEELQ 493
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+++ K+ ++ E + + Q++E K+ + Q K E + LK K
Sbjct: 494 EQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGS--KSEGESSSKLKQKLE 551
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+L + ++L+ + +++++ I +I EL A L+ K + + +E+
Sbjct: 552 AHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEE 604
Score = 57.6 bits (133), Expect = 1e-07
Identities = 66/313 (21%), Positives = 142/313 (45%), Gaps = 14/313 (4%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAIKEKLT 277
E +++ R +ET + ++ +L SES+ L L+E+ A L KE+L
Sbjct: 358 EEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLI 417
Query: 278 TTESQLRQTRNRVAKMDKQ---LREAEASITSLTGTV--KMLEDQSRQKEVQLEARARKL 332
L++T + Q L + +AS T + +++ + R+ ++L+ + L
Sbjct: 418 EQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKML 477
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQ 392
R + E + +Q++ + + + ++L+ K I++L++ ++ +++LQEQ
Sbjct: 478 RLQQEGSENERIEELQEQLEQKHRKMNELETEQRLS---KERIRELQQQIEDLQKSLQEQ 534
Query: 393 CEITKREI--ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQA 450
++ E +LK++ E ++ EELQ K +E +P+ + ++ +L A LQ
Sbjct: 535 GSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQK 594
Query: 451 TKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNE 510
E ++ E+ + + K + KL + E ++ + Q+ +E I +E
Sbjct: 595 KDEDMKAMEERYKMYLEKARNVIKT-LDPKL--NPASAEIMLLRKQLAEKERRIEILESE 651
Query: 511 QKVIQYEQYVRDL 523
KV ++ Y L
Sbjct: 652 CKVAKFRDYEEKL 664
Score = 41.5 bits (93), Expect = 0.010
Identities = 87/365 (23%), Positives = 157/365 (43%), Gaps = 60/365 (16%)
Query: 351 DSLQAEVLECKQQI---EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTE 407
+S+Q V+ Q++ E L+ A+ +LE+ LK RAL+E E + EL++R E
Sbjct: 146 ESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLK---RALEELQEALAEKEELRQRCE 202
Query: 408 ------TELQDSRNAI----EELQAKIIELEKSKPNPD-----------LPTEREIDLWA 446
T LQD +N++ E + K+ +L+ S +P+ L E+ +
Sbjct: 203 ELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENF 262
Query: 447 ELQATKETLRV--------------TEDEVTTCKRE----KESENKIGIQQKLAAELLNK 488
L+A K+ RV DE+T+ E K+ + + A +L +
Sbjct: 263 RLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLEST 322
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH--NRTIANCQESPNGISYQDLQ 546
EI + +L K +K ++ + Y L+ A Q QDL
Sbjct: 323 VEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLH 382
Query: 547 QEIMDLKMK---LLDVVHRNEELSEILAK-KDQELEQQD--KNSRGQARVIKIREELINV 600
++ + L + R EE E L K K++ +EQ+D K + + R +++++ +N
Sbjct: 383 VKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQ 442
Query: 601 LKNKETEQSRELAALQQDLEHR---MRIVDEVN----KQIAAKADEIQELFATLENKQQQ 653
T+ LAA +E+R +R+ E +Q ++ + I+EL LE K ++
Sbjct: 443 TDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRK 502
Query: 654 IHRLE 658
++ LE
Sbjct: 503 MNELE 507
>AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein.
Length = 864
Score = 69.7 bits (163), Expect = 3e-11
Identities = 101/487 (20%), Positives = 219/487 (44%), Gaps = 30/487 (6%)
Query: 187 RELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR 246
++L+ E+ + T A E + ++ + L +AKL+ ++ N+ E L
Sbjct: 51 QQLERHKEELLETADKELGEAKKEIKRKLSEMQDLEETMAKLQLEL---NLCQKEKERLS 107
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
E LE + H+L++E+ E TE QL R+ +++ ++ + S +
Sbjct: 108 DELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQLTLEVERM-RLEHGIKRRDRSPSR 166
Query: 307 LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSL--QAEVLECKQQI 364
L +K +E++ + +LE +L+ ++ +TS +++ S+ E + +I
Sbjct: 167 LDTFLKGIEEERDYYKKELE----RLQHIIQRRSCSTSYSAREKSSIFRTPEKGDYNSEI 222
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAI--EELQA 422
++T + + +Q++ E ++ +Q ++ E + E Q+ +A+ E Q
Sbjct: 223 HQIT-RERDELQRMLERFEKYMEDIQSNVKLLTAERDKLSVLYNEAQEELSALRKESTQT 281
Query: 423 ----KIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES--ENKIG 476
I+ L + + L R I AE +A +E L E+ K E E E+
Sbjct: 282 TAPHNIVSLMEKEKELALSDLRRI--MAEKEALREKLEHIEEVSLFGKSELEKTIEHLTC 339
Query: 477 IQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV-IQYEQYVRDLQAHNRTIANCQE 535
+ +L +E K E+ K+ I +E I++++ N+ KV Q +V +H +T N
Sbjct: 340 VNHQLESE---KYELKSKVLIM-KETIESLE-NKLKVQAQKFSHVAGDSSHQKTEVNSLR 394
Query: 536 SPNGI---SYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK 592
N S D Q + + +L + + L E + + + ++ QD+ + + I
Sbjct: 395 IVNEQLQRSVDDYQHRLSIKRGELESAQAQIKILEEKIDELNLKMTSQDEEAHVMKKTIG 454
Query: 593 IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
+ ++ + L+ E++ ++A LQ++L ++ + V ++ I+ + +L TL N+ +
Sbjct: 455 VIDKEKDFLQETVDEKTEKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDR 514
Query: 653 QIHRLEK 659
+I+ L +
Sbjct: 515 EINSLRR 521
Score = 58.8 bits (136), Expect = 6e-08
Identities = 78/427 (18%), Positives = 182/427 (42%), Gaps = 24/427 (5%)
Query: 224 EVAKLRQDVETRNVMIDEIR-ELRSESENTKALEEMRHELDEERTAKLAI----KEKLTT 278
E+ + ++ IDE+ ++ S+ E +++ +D+E+ EK+
Sbjct: 417 ELESAQAQIKILEEKIDELNLKMTSQDEEAHVMKKTIGVIDKEKDFLQETVDEKTEKIAN 476
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT 338
+ L VA+M + E E+S+ L T+ + + QL+A ++L E ++
Sbjct: 477 LQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQLDAAHKELDEVGRS 536
Query: 339 GEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
E+ ++ LQ ++ ++ ++++++ ++A+Q+ EE + + + E +
Sbjct: 537 REIA----FKENRRLQDDLATMARENQEISLELEAAVQEKEEMKSRVHKYITEVSR-WES 591
Query: 399 EIELKERTETELQDS----RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET 454
+ KE+ +L D N E+ + K + E + L + + E + +E
Sbjct: 592 LMAAKEKENQDLLDRFQMLHNRAEDWEVKAHQAEGESSSVRLEL---LSIDTERRHLRER 648
Query: 455 LRVTEDEVTT-CKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ + E E+ E++I K + L EE + + + ++ ++ +
Sbjct: 649 VELLEKEIQEHINAHHAYESQISSMAKAMSRL---EEELRHQEDEKATVLNDLSSLRELC 705
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILA-K 572
I+ + +D+ N + + ++++ E LK +L + H + L +LA
Sbjct: 706 IKLDSG-KDIMTQQLNSKNLEFERVVVELENVKSESDLLKKQLSNERHTVKNLESLLATN 764
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ 632
+D+E S + I++ +E + + ++K T QSRE L+ + D + +Q
Sbjct: 765 RDKEFHSH-LTSHEKDTEIQLLKEKLTLSESKLTSQSRENTMLRAKVAQLQTDYDALKRQ 823
Query: 633 IAAKADE 639
I+ + E
Sbjct: 824 ISTERYE 830
Score = 34.3 bits (75), Expect = 1.5
Identities = 35/141 (24%), Positives = 69/141 (48%), Gaps = 17/141 (12%)
Query: 375 IQQLEEDLKQTKRALQEQCE-ITKREIELKERTE---TELQDSRNAIEELQAKIIELEKS 430
+QQ +DL++ R L E E +T + L + E EL + ++L+ EL ++
Sbjct: 4 LQQANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEIDQLAQQLERHKEELLET 63
Query: 431 KPNPDLPTEREID-LWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNK- 488
++EI +E+Q +ET+ + E+ C++EKE +L+ ELL K
Sbjct: 64 ADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQKEKE---------RLSDELLVKS 114
Query: 489 --EEIIGKMQIQTRELIKNIK 507
E ++ +++ + + L K ++
Sbjct: 115 DLETVVHQLEQEKQRLSKKVE 135
>Z98949-1|CAI17892.1| 2566|Homo sapiens protein ( Human DNA sequence
from clone CTA-125H2 on chromosome 22q11-12. ).
Length = 2566
Score = 69.3 bits (162), Expect = 4e-11
Identities = 117/534 (21%), Positives = 233/534 (43%), Gaps = 44/534 (8%)
Query: 154 KTNLTVNQDQTDGDILEHLSRYNDQGFE---LCGALRELKTQAEDAVNTVTDLSKRACHE 210
+ L N D + I + S D+ F+ C L + + A V +L +
Sbjct: 1425 RNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQV 1484
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR---SESENT---KALEEMRHELDE 264
++ L V + L K++ + RN + ++R ++ EN K L++ LD
Sbjct: 1485 QKKLGDVNKQLEEAQQKIQLNDLERNPTGGDEWQMRFDCAQMENEFLRKRLQQCEERLDS 1544
Query: 265 ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT-SLTGTVKMLEDQ-SRQKE 322
E TA+ +++KL +L+ + KM QL+ +T L T +LE+Q SR E
Sbjct: 1545 ELTARKELEQKL----GELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHE 1600
Query: 323 VQLEARARKLRESLKTGEVT-----TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
++ + + L+ + GE ++ Q+ S++ E+ + +QQ+ K Q S ++Q
Sbjct: 1601 LEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQL-KQKEQEASQLKQ 1659
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERT---ETELQDSRNAIEELQAKIIELEKSKPN 433
E L+ KR L + + + LKER E+ + + + + I +LE+ +
Sbjct: 1660 QVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQR 1719
Query: 434 PDLPTEREIDLWAELQATKETLRVTEDEVTTCKR-----EKESENKIGIQQKLAAELLNK 488
+L ER + + + +E ED +C++ E + E + +Q + E +
Sbjct: 1720 FELEIERMKQMHQKDREDQE--EELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDL 1777
Query: 489 EEIIGKM--QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
E +IG + QI R+ +L + + + D+Q T+ + + S + + +
Sbjct: 1778 EGLIGTLCDQIGHRDFDVEKRLRRD-LRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVH 1836
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLKNKE 605
++ + K + + + L+ L ELE +N S ++ +++ E ++LK +
Sbjct: 1837 SQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRID 1896
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+Q DL M+ ++ Q AA +IQEL LE +++ H+L++
Sbjct: 1897 EDQD--------DLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE 1942
Score = 51.6 bits (118), Expect = 9e-06
Identities = 64/304 (21%), Positives = 126/304 (41%), Gaps = 17/304 (5%)
Query: 257 EMRHELDEERTAKLAIKEKL---TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
E R D RT L +L T + + ++ + K+ QL ++EA T K+
Sbjct: 1796 EKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKV 1855
Query: 314 LEDQSRQKEVQLEARARK---LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
L +LE R + E L + + L+++ D Q ++ E Q+ + L Q
Sbjct: 1856 LTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQ 1915
Query: 371 HKSAIQQLEE------DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI 424
+ I Q++E + K+ K LQEQ ++ + IE E++ + R + +A I
Sbjct: 1916 SAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD----RAIVSRQEAVI 1971
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+LE + +R L L+ + + + T + ++ ++ Q++L
Sbjct: 1972 CDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQY-YQRRLEEL 2030
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQD 544
+ EE++ + +R ++ K E+ + DL+ R IA+ Q + ++ D
Sbjct: 2031 KADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSD 2090
Query: 545 LQQE 548
E
Sbjct: 2091 SDTE 2094
Score = 40.7 bits (91), Expect = 0.017
Identities = 38/205 (18%), Positives = 98/205 (47%), Gaps = 10/205 (4%)
Query: 227 KLRQDVETRNVMIDEIRELRSESE-NTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
++ +D + N ++ + ++L ++S + ++E++ +L+E + K ++E+L + ++
Sbjct: 1894 RIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEY 1953
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
R+ EA I L + + Q ++ EV + +LR+SL + +
Sbjct: 1954 LEQSTVDRAIVSRQ-EAVICDLENKTEFQKVQIKRFEVLVI----RLRDSL----IKMGE 2004
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+ Q + +++ E Q ++ + K+ +++L + + R E + + +++
Sbjct: 2005 ELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQT 2064
Query: 406 TETELQDSRNAIEELQAKIIELEKS 430
+T+L+ S I +LQA + E+ S
Sbjct: 2065 LQTDLETSIRRIADLQAALEEVASS 2089
>DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein
kinase beta (DMPK-like) protein.
Length = 1711
Score = 69.3 bits (162), Expect = 4e-11
Identities = 99/404 (24%), Positives = 184/404 (45%), Gaps = 43/404 (10%)
Query: 263 DEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKE 322
DE+ L ++ E ++R+ ++ ++L+E+ ++ SL G+ + L + +R KE
Sbjct: 427 DEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKE 486
Query: 323 V-----QLEARARKLRES--LKTGEVTTSQLIQQR-DSLQA-------------EVLECK 361
+ ++E K+ +S L+ T L Q+R DS Q E E
Sbjct: 487 IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELH 546
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIE 418
+Q+ + + + KS ++L++ +Q K ALQE E+ +R EL K++ +L+D +E
Sbjct: 547 KQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEME 606
Query: 419 ELQAKIIELEKSKPNPD-LPTEREIDL-WAELQATKETLRVTEDEVTTCKREKESENKIG 476
K+ + + + L E E L A +A+KE ++ E CK+ + +
Sbjct: 607 VATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKER-KLREHSENFCKQMESELEALK 665
Query: 477 IQQ--KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTIANC 533
++Q + A L ++ I K++ + E+KV+ Y E+ VR +H + N
Sbjct: 666 VKQGGRGAGATLEHQQEISKIKSEL----------EKKVLFYEEELVRREASHVLEVKNV 715
Query: 534 -QESPNGISYQ-DLQQEIMDLKMKL-LDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
+E + S+Q LQ+EI+ LK KL R+ E+ E + + E++ + +
Sbjct: 716 KKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKK 775
Query: 591 IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA 634
+ E + +K T Q+R+L QDL + V QIA
Sbjct: 776 LTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIA 819
Score = 59.3 bits (137), Expect = 5e-08
Identities = 84/386 (21%), Positives = 173/386 (44%), Gaps = 35/386 (9%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDE-----ERTAKLAIKEKLT 277
+E+ KL +++E I + L + E+T AL + R + + E+ ++ +EK
Sbjct: 485 KEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEK-E 543
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
QL + R+ K+L++A L ++ + Q + +R+LR+ +
Sbjct: 544 ELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEE 603
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
EV T Q+ D+++ E+ ++ ++L Q A+ + ++ R L+E E
Sbjct: 604 EMEVAT----QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKE-----RKLREHSENFC 654
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
+++E + Q R A L+ + E SK +L E+++ + E +E V
Sbjct: 655 KQMESELEALKVKQGGRGAGATLEH---QQEISKIKSEL--EKKVLFYEEELVRREASHV 709
Query: 458 TEDEVTTCKRE-KESEN-KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK--LNEQKV 513
E V K+E +SE+ ++ +Q+++ E+ + + E + IK ++
Sbjct: 710 LE--VKNVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERA 767
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK 573
+ +++ + L A N + + + + Q L+ E+ DL K V H +++EI+
Sbjct: 768 MLFDEN-KKLTAENEKLCSFVDKLTAQNRQ-LEDELQDLAAKKESVAHWEAQIAEII--- 822
Query: 574 DQELEQQDKNSRG--QARVIKIREEL 597
+ +K++RG QA K+ EEL
Sbjct: 823 --QWVSDEKDARGYLQALASKMTEEL 846
Score = 39.1 bits (87), Expect = 0.052
Identities = 37/151 (24%), Positives = 73/151 (48%), Gaps = 11/151 (7%)
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+K+ + Q V+ L +R ++N + L +EI LK K+ D +L + +
Sbjct: 459 RKLQESTQTVQSLHGSSRALSNSNRDKE---IKKLNEEIERLKNKIADSNRLERQLEDTV 515
Query: 571 AKKDQELEQQDKNSRG---QARVIKI-REELINVL---KNKETEQSRELAALQQDLEHRM 623
A + QE E + RG Q RV++ +EEL L + Q++EL Q + +
Sbjct: 516 ALR-QEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLAL 574
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ E+N+++A + Q++ L +K++++
Sbjct: 575 QEFSELNERMAELRAQKQKVSRQLRDKEEEM 605
>BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein.
Length = 638
Score = 69.3 bits (162), Expect = 4e-11
Identities = 116/507 (22%), Positives = 215/507 (42%), Gaps = 48/507 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS 247
+L + + AV + +RA E R A +L R L ++ E R + + R LR+
Sbjct: 115 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA---LEEEQEAREELERQNRALRA 171
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
E LE + D+ + ++ E R +V +++ +L AE + L
Sbjct: 172 E------LEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRL 225
Query: 308 TGTVKMLEDQSRQ----KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
TV+ L+ Q + ++ E R R+L + L+ EV + +QR A + + +
Sbjct: 226 EVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGE 285
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
+E+L Q SA Q EE +KQ R +Q Q + RE+E + RT E S+N E + K
Sbjct: 286 LEELKAQMASAGQGKEEAVKQL-RKMQAQMKELWREVE-ETRTSREEIFSQNRESEKRLK 343
Query: 424 IIELEKSKPNPDLPTEREIDLWAEL---QATKETLRVTEDEVTTCKREKESENKIG-IQQ 479
+E E + +L A+ + E + + +++ E ++G +++
Sbjct: 344 GLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEE 403
Query: 480 KLAAELLNKE---EIIGKMQIQTRELIKNIKLN-------EQKVIQYEQYVRDLQA---- 525
+L E N E + K+ +Q L + E Q E+ +++L+
Sbjct: 404 ELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGE 463
Query: 526 --------HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL 577
H TIA ES + + L+QE + + V + L E++ + ++E
Sbjct: 464 EDAGARARHKMTIA-ALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 522
Query: 578 EQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAA---LQQDLEHRMRIVDEVNKQI 633
D+ R Q +R ++L L+ E E SR A LQ++LE + +N+++
Sbjct: 523 RVADQ-LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREV 581
Query: 634 AAKADEIQELFATLENKQ-QQIHRLEK 659
+ ++ T + +Q+ RLE+
Sbjct: 582 TTLRNRLRRGPLTFTTRTVRQVFRLEE 608
Score = 52.0 bits (119), Expect = 7e-06
Identities = 90/398 (22%), Positives = 174/398 (43%), Gaps = 43/398 (10%)
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+R +L+EE A+ +L T ++QL + R R +E EA G ++ E+
Sbjct: 8 LREQLEEEAAARERAGRELQTAQAQLSEWRRR--------QEEEA------GALEAGEEA 53
Query: 318 SRQKEVQLEARARKLRESLKTG---EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA 374
R+ + EA ++L E +T E +L Q+ D ++ + +Q + L + +
Sbjct: 54 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 113
Query: 375 IQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNP 434
Q L E+ RA++E+ + E E +ER L +R A+EE Q ELE+ N
Sbjct: 114 DQLLAEEKAAVLRAVEER---ERAEAEGREREARALSLTR-ALEEEQEAREELERQ--NR 167
Query: 435 DLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ-QKLAAELLNKEEIIG 493
L E E A L + + + + C+ +++ N + Q +L EL E+
Sbjct: 168 ALRAELE----ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKL 223
Query: 494 KMQI--------QTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDL 545
++++ R+L + E++ Q + +RD + R Q + + + L
Sbjct: 224 RLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV-ERDEERKQRTLAVAARKKL 282
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
+ E+ +LK ++ EE + L K ++++ + + R REE+ + +N+E
Sbjct: 283 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE-ETRT--SREEIFS--QNRE 337
Query: 606 TEQS-RELAALQQDLEHRMRIVDEVNKQIAAKADEIQE 642
+E+ + L A L+ + D +Q DE+ +
Sbjct: 338 SEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD 375
Score = 41.9 bits (94), Expect = 0.007
Identities = 75/341 (21%), Positives = 147/341 (43%), Gaps = 32/341 (9%)
Query: 325 LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ 384
+EA A LRE L+ + ++ + QA++ E +++ E + A++ EE
Sbjct: 1 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE----EEAGALEAGEE---A 53
Query: 385 TKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL--PTEREI 442
+RA +E +T+R E E + + R +EL ++LE+ + +R+
Sbjct: 54 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 113
Query: 443 D-LWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRE 501
D L AE +A LR E+ + E E + L L ++E +++ Q R
Sbjct: 114 DQLLAEEKAA--VLRAVEERE---RAEAEGREREARALSLTRALEEEQEAREELERQNRA 168
Query: 502 LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLL---D 558
L ++ + V +L+ R +++ N DL+ ++ +L+ +L D
Sbjct: 169 LRAELEALLSSKDDVGKSVHELE---RACRVAEQAAN-----DLRAQVTELEDELTAAED 220
Query: 559 VVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL--INVLKNKETEQSRELAALQ 616
R E + L K E + Q ++ G+ R ++ ++L V +++E +Q A +
Sbjct: 221 AKLRLEVTVQAL-KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAAR 279
Query: 617 QDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
+ LE + +E+ Q+A+ +E L Q Q+ L
Sbjct: 280 KKLEGEL---EELKAQMASAGQGKEEAVKQLRKMQAQMKEL 317
Score = 35.5 bits (78), Expect = 0.64
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 7/115 (6%)
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK 604
LQQE+ D M L + +L L KK ++ +Q + A V++ EE
Sbjct: 85 LQQELDDATMDL----EQQRQLVSTLEKKQRKFDQLLAEEK--AAVLRAVEERERAEAEG 138
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
++R L+ L + LE +E+ +Q A E++ L ++ ++ + +H LE+
Sbjct: 139 REREARALS-LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER 192
>BC108282-1|AAI08283.1| 723|Homo sapiens Unknown (protein for
IMAGE:3855371) protein.
Length = 723
Score = 69.3 bits (162), Expect = 4e-11
Identities = 102/448 (22%), Positives = 219/448 (48%), Gaps = 44/448 (9%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
++ + LRQ +T+ +++E + E + K +E E+ ++ T+K A +LT+++
Sbjct: 186 IKALETLRQVRQTQG---QKVKEYQMELKYLKQYKEKACEIRDQITSKEA---QLTSSKE 239
Query: 282 QLRQTRNRVAKMDKQLREAE---ASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL-K 337
++ N + + +L+E E + I L +K L+ SR+K Q+E +L E + K
Sbjct: 240 IVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALD--SRKK--QMEKDNSELEEKMEK 295
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
+ T QL + Q V E ++ KL H+ +LE+ K+++ QE+ E+
Sbjct: 296 VFQGTDEQLNDLYHNHQRTVREKER---KLVDCHR----ELEKLNKESRLLNQEKSELLV 348
Query: 398 RE--IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKET 454
+ ++L+ E +R+++ + A +EL+ + P +ER+I + +L + +E
Sbjct: 349 EQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPF--SERQIKNFHKLVRERQEG 406
Query: 455 LRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI 514
T +++ EKE+ ++QK E+ +K+ +G++ I+ + I + K NE K +
Sbjct: 407 EAKTANQLMNDFAEKET-----LKQKQIDEIRDKKTGLGRI-IELKSEILSKKQNELKNV 460
Query: 515 QYEQYVRDLQAHNRTIANCQE----SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+YE ++ L+ + I + + +S + + LKM+++ + + +L L
Sbjct: 461 KYE--LQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTL 518
Query: 571 AKKDQELEQQDKN--SRGQARVI-KIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
K DQE+EQ + + +R Q ++ K + + ++ ++ S EL +L ++ ++ D
Sbjct: 519 RKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKKQLED 578
Query: 628 ---EVNKQIAAKADEIQELFATLENKQQ 652
+K+I D + +L L + +Q
Sbjct: 579 WLHSKSKEINQTRDRLAKLNKELASSEQ 606
Score = 41.9 bits (94), Expect = 0.007
Identities = 57/248 (22%), Positives = 108/248 (43%), Gaps = 18/248 (7%)
Query: 181 ELCGALREL-KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMI 239
EL A REL K + V T+ +E+ L L +E+ +L TR M
Sbjct: 480 ELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQME 539
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLA-------IKEKLTTTESQLRQTRNRVAK 292
++ + E + ++ RH +E T+ L +++ L + ++ QTR+R+AK
Sbjct: 540 MLTKDKADKDEQIRKIKS-RHS--DELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAK 596
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQL--EARARKLRESLKTGEVTTSQLIQQR 350
++K+L +E + + +K E+Q E +L ++ L + + +QR
Sbjct: 597 LNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQR 656
Query: 351 DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK----ERT 406
L Q I +LT +++S + + QT+ LQE + ++ L + T
Sbjct: 657 AMLAGATAVYSQFITQLTDENQSCCPVCQR-VFQTEAELQEVISDLQSKLRLAPDKLKST 715
Query: 407 ETELQDSR 414
E+EL+ +
Sbjct: 716 ESELKKKK 723
Score = 39.1 bits (87), Expect = 0.052
Identities = 90/467 (19%), Positives = 191/467 (40%), Gaps = 44/467 (9%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENT-----KALEEMRHELDEERTAKLAIKEKLTT 278
+ ++R + ++ + +E+ EN L+E+ H L + IK L +
Sbjct: 219 KACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKA-LDS 277
Query: 279 TESQLRQTRNRVA-KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
+ Q+ + + + KM+K + + + L + + +K V KL + +
Sbjct: 278 RKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESR 337
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
S+L+ ++ LQ + ++ I +S QLE D +R + +I
Sbjct: 338 LLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELD--GFERGPFSERQIKN 395
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ER E E + + + + K E K K ++ +++ L ++ E L
Sbjct: 396 FHKLVRERQEGEAKTANQLMNDFAEK--ETLKQKQIDEI-RDKKTGLGRIIELKSEILSK 452
Query: 458 TEDEVTTCKREKE-----SENKIGIQQKL--AAELLNKEEIIGKMQIQTRELI--KNIKL 508
++E+ K E + S+ + + Q+L A L+K E ++ E+I +N K
Sbjct: 453 KQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKA 512
Query: 509 NEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQDLQ---------QEIMDL------ 552
+ + ++ +Q + L H T + + +D Q E+ L
Sbjct: 513 DLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPN 572
Query: 553 KMKLLDVVH-RNEELSEI---LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQ 608
K +L D +H +++E+++ LAK ++EL ++N +K +EE ++ ++K +
Sbjct: 573 KKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDV 632
Query: 609 SRELAALQQDLEHRMRIVDEVNKQIA--AKADEIQELFATLENKQQQ 653
+ DL+ +++ +KQ A A A + F T + Q
Sbjct: 633 CGS-QDFESDLDRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQ 678
>BC073850-1|AAH73850.1| 723|Homo sapiens RAD50 protein protein.
Length = 723
Score = 69.3 bits (162), Expect = 4e-11
Identities = 102/448 (22%), Positives = 219/448 (48%), Gaps = 44/448 (9%)
Query: 222 VREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTES 281
++ + LRQ +T+ +++E + E + K +E E+ ++ T+K A +LT+++
Sbjct: 186 IKALETLRQVRQTQG---QKVKEYQMELKYLKQYKEKACEIRDQITSKEA---QLTSSKE 239
Query: 282 QLRQTRNRVAKMDKQLREAE---ASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL-K 337
++ N + + +L+E E + I L +K L+ SR+K Q+E +L E + K
Sbjct: 240 IVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALD--SRKK--QMEKDNSELEEKMEK 295
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
+ T QL + Q V E ++ KL H+ +LE+ K+++ QE+ E+
Sbjct: 296 VFQGTDEQLNDLYHNHQRTVREKER---KLVDCHR----ELEKLNKESRLLNQEKSELLV 348
Query: 398 RE--IELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKET 454
+ ++L+ E +R+++ + A +EL+ + P +ER+I + +L + +E
Sbjct: 349 EQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPF--SERQIKNFHKLVRERQEG 406
Query: 455 LRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI 514
T +++ EKE+ ++QK E+ +K+ +G++ I+ + I + K NE K +
Sbjct: 407 EAKTANQLMNDFAEKET-----LKQKQIDEIRDKKTGLGRI-IELKSEILSKKQNELKNV 460
Query: 515 QYEQYVRDLQAHNRTIANCQE----SPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+YE ++ L+ + I + + +S + + LKM+++ + + +L L
Sbjct: 461 KYE--LQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTL 518
Query: 571 AKKDQELEQQDKN--SRGQARVI-KIREELINVLKNKETEQSRELAALQQDLEHRMRIVD 627
K DQE+EQ + + +R Q ++ K + + ++ ++ S EL +L ++ ++ D
Sbjct: 519 RKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKKQLED 578
Query: 628 ---EVNKQIAAKADEIQELFATLENKQQ 652
+K+I D + +L L + +Q
Sbjct: 579 WLHSKSKEINQTRDRLAKLNKELASSEQ 606
Score = 41.9 bits (94), Expect = 0.007
Identities = 57/248 (22%), Positives = 108/248 (43%), Gaps = 18/248 (7%)
Query: 181 ELCGALREL-KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMI 239
EL A REL K + V T+ +E+ L L +E+ +L TR M
Sbjct: 480 ELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQME 539
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLA-------IKEKLTTTESQLRQTRNRVAK 292
++ + E + ++ RH +E T+ L +++ L + ++ QTR+R+AK
Sbjct: 540 MLTKDKADKDEQIRKIKS-RHS--DELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAK 596
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQL--EARARKLRESLKTGEVTTSQLIQQR 350
++K+L +E + + +K E+Q E +L ++ L + + +QR
Sbjct: 597 LNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDLDRLKEEIEKSSKQR 656
Query: 351 DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK----ERT 406
L Q I +LT +++S + + QT+ LQE + ++ L + T
Sbjct: 657 AMLAGATAVYSQFITQLTDENQSCCPVCQR-VFQTEAELQEVISDLQSKLRLAPDKLKST 715
Query: 407 ETELQDSR 414
E+EL+ +
Sbjct: 716 ESELKKKK 723
Score = 39.1 bits (87), Expect = 0.052
Identities = 90/467 (19%), Positives = 191/467 (40%), Gaps = 44/467 (9%)
Query: 224 EVAKLRQDVETRNVMIDEIRELRSESENT-----KALEEMRHELDEERTAKLAIKEKLTT 278
+ ++R + ++ + +E+ EN L+E+ H L + IK L +
Sbjct: 219 KACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKA-LDS 277
Query: 279 TESQLRQTRNRVA-KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
+ Q+ + + + KM+K + + + L + + +K V KL + +
Sbjct: 278 RKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESR 337
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
S+L+ ++ LQ + ++ I +S QLE D +R + +I
Sbjct: 338 LLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELD--GFERGPFSERQIKN 395
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
++ER E E + + + + K E K K ++ +++ L ++ E L
Sbjct: 396 FHKLVRERQEGEAKTANQLMNDFAEK--ETLKQKQIDEI-RDKKTGLGRIIELKSEILSK 452
Query: 458 TEDEVTTCKREKE-----SENKIGIQQKL--AAELLNKEEIIGKMQIQTRELI--KNIKL 508
++E+ K E + S+ + + Q+L A L+K E ++ E+I +N K
Sbjct: 453 KQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKA 512
Query: 509 NEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQDLQ---------QEIMDL------ 552
+ + ++ +Q + L H T + + +D Q E+ L
Sbjct: 513 DLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPN 572
Query: 553 KMKLLDVVH-RNEELSEI---LAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQ 608
K +L D +H +++E+++ LAK ++EL ++N +K +EE ++ ++K +
Sbjct: 573 KKQLEDWLHSKSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDV 632
Query: 609 SRELAALQQDLEHRMRIVDEVNKQIA--AKADEIQELFATLENKQQQ 653
+ DL+ +++ +KQ A A A + F T + Q
Sbjct: 633 CGS-QDFESDLDRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQ 678
>BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein.
Length = 933
Score = 69.3 bits (162), Expect = 4e-11
Identities = 99/404 (24%), Positives = 184/404 (45%), Gaps = 43/404 (10%)
Query: 263 DEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKE 322
DE+ L ++ E ++R+ ++ ++L+E+ ++ SL G+ + L + +R KE
Sbjct: 427 DEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKE 486
Query: 323 V-----QLEARARKLRES--LKTGEVTTSQLIQQR-DSLQA-------------EVLECK 361
+ ++E K+ +S L+ T L Q+R DS Q E E
Sbjct: 487 IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELH 546
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIE 418
+Q+ + + + KS ++L++ +Q K ALQE E+ +R EL K++ +L+D +E
Sbjct: 547 KQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEME 606
Query: 419 ELQAKIIELEKSKPNPD-LPTEREIDL-WAELQATKETLRVTEDEVTTCKREKESENKIG 476
K+ + + + L E E L A +A+KE ++ E CK+ + +
Sbjct: 607 VATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKER-KLREHSENFCKQMESELEALK 665
Query: 477 IQQ--KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTIANC 533
++Q + A L ++ I K++ + E+KV+ Y E+ VR +H + N
Sbjct: 666 VKQGGRGAGATLEHQQEISKIKSEL----------EKKVLFYEEELVRREASHVLEVKNV 715
Query: 534 -QESPNGISYQ-DLQQEIMDLKMKL-LDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
+E + S+Q LQ+EI+ LK KL R+ E+ E + + E++ + +
Sbjct: 716 KKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKK 775
Query: 591 IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA 634
+ E + +K T Q+R+L QDL + V QIA
Sbjct: 776 LTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIA 819
Score = 59.3 bits (137), Expect = 5e-08
Identities = 84/386 (21%), Positives = 173/386 (44%), Gaps = 35/386 (9%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDE-----ERTAKLAIKEKLT 277
+E+ KL +++E I + L + E+T AL + R + + E+ ++ +EK
Sbjct: 485 KEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEK-E 543
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
QL + R+ K+L++A L ++ + Q + +R+LR+ +
Sbjct: 544 ELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEE 603
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
EV T Q+ D+++ E+ ++ ++L Q A+ + ++ R L+E E
Sbjct: 604 EMEVAT----QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKE-----RKLREHSENFC 654
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
+++E + Q R A L+ + E SK +L E+++ + E +E V
Sbjct: 655 KQMESELEALKVKQGGRGAGATLEH---QQEISKIKSEL--EKKVLFYEEELVRREASHV 709
Query: 458 TEDEVTTCKRE-KESEN-KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK--LNEQKV 513
E V K+E +SE+ ++ +Q+++ E+ + + E + IK ++
Sbjct: 710 LE--VKNVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERA 767
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK 573
+ +++ + L A N + + + + Q L+ E+ DL K V H +++EI+
Sbjct: 768 MLFDEN-KKLTAENEKLCSFVDKLTAQNRQ-LEDELQDLAAKKESVAHWEAQIAEII--- 822
Query: 574 DQELEQQDKNSRG--QARVIKIREEL 597
+ +K++RG QA K+ EEL
Sbjct: 823 --QWVSDEKDARGYLQALASKMTEEL 846
Score = 39.1 bits (87), Expect = 0.052
Identities = 37/151 (24%), Positives = 73/151 (48%), Gaps = 11/151 (7%)
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+K+ + Q V+ L +R ++N + L +EI LK K+ D +L + +
Sbjct: 459 RKLQESTQTVQSLHGSSRALSNSNRDKE---IKKLNEEIERLKNKIADSNRLERQLEDTV 515
Query: 571 AKKDQELEQQDKNSRG---QARVIKI-REELINVL---KNKETEQSRELAALQQDLEHRM 623
A + QE E + RG Q RV++ +EEL L + Q++EL Q + +
Sbjct: 516 ALR-QEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLAL 574
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ E+N+++A + Q++ L +K++++
Sbjct: 575 QEFSELNERMAELRAQKQKVSRQLRDKEEEM 605
>BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein.
Length = 2002
Score = 69.3 bits (162), Expect = 4e-11
Identities = 111/549 (20%), Positives = 240/549 (43%), Gaps = 38/549 (6%)
Query: 137 LELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDA 196
+E+++ + +I+ + N V+ D G E +Y E+ + L+ + ED
Sbjct: 1340 MEVMEMEVMEARLIRAAEINGEVDDDDAGG---EWRLKYERAVREVDFTKKRLQQEFEDK 1396
Query: 197 VNTVTDLSKRACHERR-TLIAVGEALVREVAKLRQDVETRNVMIDEIR-ELRSESENTKA 254
+ V +KR R L A E R + +L++ + + + + L +
Sbjct: 1397 LE-VEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
Query: 255 LEEMRHELDEE--RTAKLAIKEKLTTTESQLRQTR--NRVAKMDKQLREAEASITSLTGT 310
LE+ + D E + + A +EKL + Q + + +QL E + I T
Sbjct: 1456 LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQK 1515
Query: 311 VKMLEDQSRQ---KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
V LE + + +E + EA K+++ L+ E ++ D QA ++ +Q++++
Sbjct: 1516 VVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE-QAGTIQMLEQLKQM 1574
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQC-----EITKREIELKERTETELQDSRNAIEELQA 422
VQ + + ++ L++ KR L+ + ++ +R+ E ++R +L+ ++ + + Q
Sbjct: 1575 EVQLEEEYEDKQKVLRE-KRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQL 1633
Query: 423 KIIELEKSKPNP----DLPTEREIDLWAELQATKETLRV-TEDEVTTCKREKESENKIGI 477
+ L+ S P+ L + E + A K + E E + + ++ K +
Sbjct: 1634 MLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL 1693
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ---YVRDLQAHNRTIANCQ 534
+++L+ K EI +++ ++ + +K ++ V Q + + DLQA AN +
Sbjct: 1694 EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE-ANKE 1752
Query: 535 ESPNGISYQDLQQEIMDLKMKLLD--VVHRNE-ELSEILAKKDQELEQ----QDKNSRGQ 587
+ Q LQ ++ L+ ++D +V R E ++ E+ + + E Q + SR +
Sbjct: 1753 KQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLK 1812
Query: 588 ARVIKIREELINVL--KNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFA 645
+ K+ EE + +N+E EQ++ L +D + M + + + K E++
Sbjct: 1813 ENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLE 1872
Query: 646 TLENKQQQI 654
+LE Q +
Sbjct: 1873 SLEAANQSL 1881
Score = 52.8 bits (121), Expect = 4e-06
Identities = 81/404 (20%), Positives = 176/404 (43%), Gaps = 32/404 (7%)
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
++LR K EE ELDE+ + + E+L E QL + K+ ++ RE E
Sbjct: 1542 KQLRDLEAKVKDQEE---ELDEQ-AGTIQMLEQLKQMEVQLEEEYEDKQKVLREKRELEG 1597
Query: 303 SITSLTGTVKMLEDQSRQ---KEVQ----LEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
+ +L+ V + +S + K+++ L A A+ + + LK + ++ Q ++ L+
Sbjct: 1598 KLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEE 1657
Query: 356 EVLECKQQIEK---LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
C ++ + V+ + Q++ D+ + K AL+EQ +RE + E+Q
Sbjct: 1658 SEFTCAAAVKARKAMEVEIEDLHLQID-DIAKAKTALEEQLSRLQRE-------KNEIQ- 1708
Query: 413 SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
N +EE Q + EL K R++ +LQA E + E+ + +S+
Sbjct: 1709 --NRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQ 1766
Query: 473 NKIGIQQKLAAELLNKEEI-IGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
+ Q + L++++E I +++ + +K E + ++ + L R
Sbjct: 1767 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKL-TEERDQR 1825
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVI 591
E+ + LQ+++ D K ++ ++ + E S + + +LE + ++ +
Sbjct: 1826 IAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADL 1885
Query: 592 KIREELINVLK-----NKETEQSRELAALQQDLEHRMRIVDEVN 630
K+ + I L+ E++++ +L + D + + D V+
Sbjct: 1886 KLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVD 1929
Score = 52.0 bits (119), Expect = 7e-06
Identities = 92/471 (19%), Positives = 207/471 (43%), Gaps = 43/471 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA-KLRQDVETRNVMIDEIRELR 246
EL+ ++ + +++L+ ER T + + L E A +LR + E++EL+
Sbjct: 1279 ELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAE--------KEMKELQ 1330
Query: 247 SESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
++ + K +E M E+ E R + A + + R K ++ +RE + +
Sbjct: 1331 TQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR---LKYERAVREVDFTKK 1387
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L + + +Q + QLE R L+ + + QL ++ L AE+ + K +E
Sbjct: 1388 RLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1447
Query: 366 KLTVQ-HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI 424
V+ H+ +Q D + ++ + Q E +RE +L+ + L ++ + ++L+ K
Sbjct: 1448 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE-KLQREKDMLLAEAFSLKQQLEEKD 1506
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+++ T++ + L AELQ + ++DE + K +K+ + L A+
Sbjct: 1507 MDIAGF-------TQKVVSLEAELQDISS--QESKDEASLAKVKKQLRD-------LEAK 1550
Query: 485 LLNKEEIIGKM--QIQTRELIKNIKLN-EQKVIQYEQYVRDLQAHNRTIANCQESPNGIS 541
+ ++EE + + IQ E +K +++ E++ ++ +R+ + +A + N
Sbjct: 1551 VKDQEEELDEQAGTIQMLEQLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRD 1610
Query: 542 YQDLQQEIMDLK---------MKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIK 592
++ ++ DLK +LD + + +A+ +LE+ + + K
Sbjct: 1611 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK 1670
Query: 593 IREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
E I L + + ++ AL++ L R +E+ ++ +++ EL
Sbjct: 1671 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL 1721
Score = 39.9 bits (89), Expect = 0.030
Identities = 48/221 (21%), Positives = 96/221 (43%), Gaps = 18/221 (8%)
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
E+Q ++E +R ++E+ + + E K + +L N + + ++ T EL
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRL-----NSDRLESRISELTSELT--- 1299
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEE 565
+E+ + + D + R A + Y L++++ ++M++++ + R E
Sbjct: 1300 --DERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1357
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQS------RELAALQQD 618
++ + D E + K R V ++ L ++K E EQ R L LQ D
Sbjct: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417
Query: 619 LEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
E R + ++ K+ E+Q+ LE +Q + H LEK
Sbjct: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
Score = 37.1 bits (82), Expect = 0.21
Identities = 38/161 (23%), Positives = 73/161 (45%), Gaps = 16/161 (9%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D+ L N + EL L+ L++Q E ++ D ++L++ EA +RE
Sbjct: 1741 DLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD---------KSLVSRQEAKIRE-- 1789
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
L +E + + L S + +E++ E D+ A+ KE+ + QLR T
Sbjct: 1790 -LETRLEFERTQVKRLESLASRLKEN--MEKLTEERDQRIAAENREKEQNKRLQRQLRDT 1846
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLE--DQSRQKEVQL 325
+ + ++ ++ EA L ++ LE +QS Q +++L
Sbjct: 1847 KEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKL 1887
>AL080245-1|CAI16965.1| 2566|Homo sapiens protein ( Human DNA sequence
from clone RP11-89B2 on chromosome 22. ).
Length = 2566
Score = 69.3 bits (162), Expect = 4e-11
Identities = 117/534 (21%), Positives = 233/534 (43%), Gaps = 44/534 (8%)
Query: 154 KTNLTVNQDQTDGDILEHLSRYNDQGFE---LCGALRELKTQAEDAVNTVTDLSKRACHE 210
+ L N D + I + S D+ F+ C L + + A V +L +
Sbjct: 1425 RNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQV 1484
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR---SESENT---KALEEMRHELDE 264
++ L V + L K++ + RN + ++R ++ EN K L++ LD
Sbjct: 1485 QKKLGDVNKQLEEAQQKIQLNDLERNPTGGDEWQMRFDCAQMENEFLRKRLQQCEERLDS 1544
Query: 265 ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT-SLTGTVKMLEDQ-SRQKE 322
E TA+ +++KL +L+ + KM QL+ +T L T +LE+Q SR E
Sbjct: 1545 ELTARKELEQKL----GELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHE 1600
Query: 323 VQLEARARKLRESLKTGEVT-----TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
++ + + L+ + GE ++ Q+ S++ E+ + +QQ+ K Q S ++Q
Sbjct: 1601 LEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQL-KQKEQEASQLKQ 1659
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERT---ETELQDSRNAIEELQAKIIELEKSKPN 433
E L+ KR L + + + LKER E+ + + + + I +LE+ +
Sbjct: 1660 QVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQR 1719
Query: 434 PDLPTEREIDLWAELQATKETLRVTEDEVTTCKR-----EKESENKIGIQQKLAAELLNK 488
+L ER + + + +E ED +C++ E + E + +Q + E +
Sbjct: 1720 FELEIERMKQMHQKDREDQE--EELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDL 1777
Query: 489 EEIIGKM--QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
E +IG + QI R+ +L + + + D+Q T+ + + S + + +
Sbjct: 1778 EGLIGTLCDQIGHRDFDVEKRLRRD-LRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVH 1836
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLKNKE 605
++ + K + + + L+ L ELE +N S ++ +++ E ++LK +
Sbjct: 1837 SQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRID 1896
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+Q DL M+ ++ Q AA +IQEL LE +++ H+L++
Sbjct: 1897 EDQD--------DLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE 1942
Score = 51.6 bits (118), Expect = 9e-06
Identities = 64/304 (21%), Positives = 126/304 (41%), Gaps = 17/304 (5%)
Query: 257 EMRHELDEERTAKLAIKEKL---TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
E R D RT L +L T + + ++ + K+ QL ++EA T K+
Sbjct: 1796 EKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKV 1855
Query: 314 LEDQSRQKEVQLEARARK---LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
L +LE R + E L + + L+++ D Q ++ E Q+ + L Q
Sbjct: 1856 LTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQ 1915
Query: 371 HKSAIQQLEE------DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI 424
+ I Q++E + K+ K LQEQ ++ + IE E++ + R + +A I
Sbjct: 1916 SAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD----RAIVSRQEAVI 1971
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+LE + +R L L+ + + + T + ++ ++ Q++L
Sbjct: 1972 CDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQY-YQRRLEEL 2030
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQD 544
+ EE++ + +R ++ K E+ + DL+ R IA+ Q + ++ D
Sbjct: 2031 KADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSD 2090
Query: 545 LQQE 548
E
Sbjct: 2091 SDTE 2094
Score = 40.7 bits (91), Expect = 0.017
Identities = 38/205 (18%), Positives = 98/205 (47%), Gaps = 10/205 (4%)
Query: 227 KLRQDVETRNVMIDEIRELRSESE-NTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
++ +D + N ++ + ++L ++S + ++E++ +L+E + K ++E+L + ++
Sbjct: 1894 RIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEY 1953
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
R+ EA I L + + Q ++ EV + +LR+SL + +
Sbjct: 1954 LEQSTVDRAIVSRQ-EAVICDLENKTEFQKVQIKRFEVLVI----RLRDSL----IKMGE 2004
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+ Q + +++ E Q ++ + K+ +++L + + R E + + +++
Sbjct: 2005 ELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQT 2064
Query: 406 TETELQDSRNAIEELQAKIIELEKS 430
+T+L+ S I +LQA + E+ S
Sbjct: 2065 LQTDLETSIRRIADLQAALEEVASS 2089
>AL079300-1|CAI17881.1| 2566|Homo sapiens protein ( Human DNA sequence
from clone CTA-109D1 on chromosome 22. ).
Length = 2566
Score = 69.3 bits (162), Expect = 4e-11
Identities = 117/534 (21%), Positives = 233/534 (43%), Gaps = 44/534 (8%)
Query: 154 KTNLTVNQDQTDGDILEHLSRYNDQGFE---LCGALRELKTQAEDAVNTVTDLSKRACHE 210
+ L N D + I + S D+ F+ C L + + A V +L +
Sbjct: 1425 RNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQV 1484
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR---SESENT---KALEEMRHELDE 264
++ L V + L K++ + RN + ++R ++ EN K L++ LD
Sbjct: 1485 QKKLGDVNKQLEEAQQKIQLNDLERNPTGGDEWQMRFDCAQMENEFLRKRLQQCEERLDS 1544
Query: 265 ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT-SLTGTVKMLEDQ-SRQKE 322
E TA+ +++KL +L+ + KM QL+ +T L T +LE+Q SR E
Sbjct: 1545 ELTARKELEQKL----GELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHE 1600
Query: 323 VQLEARARKLRESLKTGEVT-----TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
++ + + L+ + GE ++ Q+ S++ E+ + +QQ+ K Q S ++Q
Sbjct: 1601 LEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQL-KQKEQEASQLKQ 1659
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERT---ETELQDSRNAIEELQAKIIELEKSKPN 433
E L+ KR L + + + LKER E+ + + + + I +LE+ +
Sbjct: 1660 QVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQR 1719
Query: 434 PDLPTEREIDLWAELQATKETLRVTEDEVTTCKR-----EKESENKIGIQQKLAAELLNK 488
+L ER + + + +E ED +C++ E + E + +Q + E +
Sbjct: 1720 FELEIERMKQMHQKDREDQE--EELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDL 1777
Query: 489 EEIIGKM--QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
E +IG + QI R+ +L + + + D+Q T+ + + S + + +
Sbjct: 1778 EGLIGTLCDQIGHRDFDVEKRLRRD-LRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVH 1836
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLKNKE 605
++ + K + + + L+ L ELE +N S ++ +++ E ++LK +
Sbjct: 1837 SQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRID 1896
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+Q DL M+ ++ Q AA +IQEL LE +++ H+L++
Sbjct: 1897 EDQD--------DLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE 1942
Score = 51.6 bits (118), Expect = 9e-06
Identities = 64/304 (21%), Positives = 126/304 (41%), Gaps = 17/304 (5%)
Query: 257 EMRHELDEERTAKLAIKEKL---TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
E R D RT L +L T + + ++ + K+ QL ++EA T K+
Sbjct: 1796 EKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKV 1855
Query: 314 LEDQSRQKEVQLEARARK---LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
L +LE R + E L + + L+++ D Q ++ E Q+ + L Q
Sbjct: 1856 LTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQ 1915
Query: 371 HKSAIQQLEE------DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI 424
+ I Q++E + K+ K LQEQ ++ + IE E++ + R + +A I
Sbjct: 1916 SAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD----RAIVSRQEAVI 1971
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+LE + +R L L+ + + + T + ++ ++ Q++L
Sbjct: 1972 CDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQY-YQRRLEEL 2030
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQD 544
+ EE++ + +R ++ K E+ + DL+ R IA+ Q + ++ D
Sbjct: 2031 KADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSD 2090
Query: 545 LQQE 548
E
Sbjct: 2091 SDTE 2094
Score = 40.7 bits (91), Expect = 0.017
Identities = 38/205 (18%), Positives = 98/205 (47%), Gaps = 10/205 (4%)
Query: 227 KLRQDVETRNVMIDEIRELRSESE-NTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
++ +D + N ++ + ++L ++S + ++E++ +L+E + K ++E+L + ++
Sbjct: 1894 RIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEY 1953
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
R+ EA I L + + Q ++ EV + +LR+SL + +
Sbjct: 1954 LEQSTVDRAIVSRQ-EAVICDLENKTEFQKVQIKRFEVLVI----RLRDSL----IKMGE 2004
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+ Q + +++ E Q ++ + K+ +++L + + R E + + +++
Sbjct: 2005 ELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQT 2064
Query: 406 TETELQDSRNAIEELQAKIIELEKS 430
+T+L+ S I +LQA + E+ S
Sbjct: 2065 LQTDLETSIRRIADLQAALEEVASS 2089
>AL022329-3|CAI17968.1| 2566|Homo sapiens protein ( Human DNA sequence
from clone CTA-407F11 on chromosome 22q12. ).
Length = 2566
Score = 69.3 bits (162), Expect = 4e-11
Identities = 117/534 (21%), Positives = 233/534 (43%), Gaps = 44/534 (8%)
Query: 154 KTNLTVNQDQTDGDILEHLSRYNDQGFE---LCGALRELKTQAEDAVNTVTDLSKRACHE 210
+ L N D + I + S D+ F+ C L + + A V +L +
Sbjct: 1425 RNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQV 1484
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELR---SESENT---KALEEMRHELDE 264
++ L V + L K++ + RN + ++R ++ EN K L++ LD
Sbjct: 1485 QKKLGDVNKQLEEAQQKIQLNDLERNPTGGDEWQMRFDCAQMENEFLRKRLQQCEERLDS 1544
Query: 265 ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT-SLTGTVKMLEDQ-SRQKE 322
E TA+ +++KL +L+ + KM QL+ +T L T +LE+Q SR E
Sbjct: 1545 ELTARKELEQKL----GELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHE 1600
Query: 323 VQLEARARKLRESLKTGEVT-----TSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
++ + + L+ + GE ++ Q+ S++ E+ + +QQ+ K Q S ++Q
Sbjct: 1601 LEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQL-KQKEQEASQLKQ 1659
Query: 378 LEEDLKQTKRALQEQCEITKREIE-LKERT---ETELQDSRNAIEELQAKIIELEKSKPN 433
E L+ KR L + + + LKER E+ + + + + I +LE+ +
Sbjct: 1660 QVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQR 1719
Query: 434 PDLPTEREIDLWAELQATKETLRVTEDEVTTCKR-----EKESENKIGIQQKLAAELLNK 488
+L ER + + + +E ED +C++ E + E + +Q + E +
Sbjct: 1720 FELEIERMKQMHQKDREDQE--EELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDL 1777
Query: 489 EEIIGKM--QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
E +IG + QI R+ +L + + + D+Q T+ + + S + + +
Sbjct: 1778 EGLIGTLCDQIGHRDFDVEKRLRRD-LRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVH 1836
Query: 547 QEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLKNKE 605
++ + K + + + L+ L ELE +N S ++ +++ E ++LK +
Sbjct: 1837 SQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRID 1896
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+Q DL M+ ++ Q AA +IQEL LE +++ H+L++
Sbjct: 1897 EDQD--------DLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQE 1942
Score = 51.6 bits (118), Expect = 9e-06
Identities = 64/304 (21%), Positives = 126/304 (41%), Gaps = 17/304 (5%)
Query: 257 EMRHELDEERTAKLAIKEKL---TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKM 313
E R D RT L +L T + + ++ + K+ QL ++EA T K+
Sbjct: 1796 EKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKV 1855
Query: 314 LEDQSRQKEVQLEARARK---LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQ 370
L +LE R + E L + + L+++ D Q ++ E Q+ + L Q
Sbjct: 1856 LTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQ 1915
Query: 371 HKSAIQQLEE------DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI 424
+ I Q++E + K+ K LQEQ ++ + IE E++ + R + +A I
Sbjct: 1916 SAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD----RAIVSRQEAVI 1971
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+LE + +R L L+ + + + T + ++ ++ Q++L
Sbjct: 1972 CDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQY-YQRRLEEL 2030
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQD 544
+ EE++ + +R ++ K E+ + DL+ R IA+ Q + ++ D
Sbjct: 2031 KADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSD 2090
Query: 545 LQQE 548
E
Sbjct: 2091 SDTE 2094
Score = 40.7 bits (91), Expect = 0.017
Identities = 38/205 (18%), Positives = 98/205 (47%), Gaps = 10/205 (4%)
Query: 227 KLRQDVETRNVMIDEIRELRSESE-NTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQ 285
++ +D + N ++ + ++L ++S + ++E++ +L+E + K ++E+L + ++
Sbjct: 1894 RIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEY 1953
Query: 286 TRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
R+ EA I L + + Q ++ EV + +LR+SL + +
Sbjct: 1954 LEQSTVDRAIVSRQ-EAVICDLENKTEFQKVQIKRFEVLVI----RLRDSL----IKMGE 2004
Query: 346 LIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKER 405
+ Q + +++ E Q ++ + K+ +++L + + R E + + +++
Sbjct: 2005 ELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQT 2064
Query: 406 TETELQDSRNAIEELQAKIIELEKS 430
+T+L+ S I +LQA + E+ S
Sbjct: 2065 LQTDLETSIRRIADLQAALEEVASS 2089
>AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens
cDNA FLJ13881 fis, clone THYRO1001458, moderately
similar to MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 545
Score = 69.3 bits (162), Expect = 4e-11
Identities = 116/507 (22%), Positives = 215/507 (42%), Gaps = 48/507 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS 247
+L + + AV + +RA E R A +L R L ++ E R + + R LR+
Sbjct: 22 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA---LEEEQEAREELERQNRALRA 78
Query: 248 ESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
E LE + D+ + ++ E R +V +++ +L AE + L
Sbjct: 79 E------LEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRL 132
Query: 308 TGTVKMLEDQSRQ----KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQ 363
TV+ L+ Q + ++ E R R+L + L+ EV + +QR A + + +
Sbjct: 133 EVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGE 192
Query: 364 IEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
+E+L Q SA Q EE +KQ R +Q Q + RE+E + RT E S+N E + K
Sbjct: 193 LEELKAQMASAGQGKEEAVKQL-RKMQAQMKELWREVE-ETRTSREEIFSQNRESEKRLK 250
Query: 424 IIELEKSKPNPDLPTEREIDLWAEL---QATKETLRVTEDEVTTCKREKESENKIG-IQQ 479
+E E + +L A+ + E + + +++ E ++G +++
Sbjct: 251 GLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEE 310
Query: 480 KLAAELLNKE---EIIGKMQIQTRELIKNIKLN-------EQKVIQYEQYVRDLQA---- 525
+L E N E + K+ +Q L + E Q E+ +++L+
Sbjct: 311 ELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGE 370
Query: 526 --------HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQEL 577
H TIA ES + + L+QE + + V + L E++ + ++E
Sbjct: 371 EDAGARARHKMTIA-ALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 429
Query: 578 EQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAA---LQQDLEHRMRIVDEVNKQI 633
D+ R Q +R ++L L+ E E SR A LQ++LE + +N+++
Sbjct: 430 RVADQ-LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREV 488
Query: 634 AAKADEIQELFATLENKQ-QQIHRLEK 659
+ ++ T + +Q+ RLE+
Sbjct: 489 TTLRNRLRRGPLTFTTRTVRQVFRLEE 515
>AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1711
Score = 69.3 bits (162), Expect = 4e-11
Identities = 99/404 (24%), Positives = 184/404 (45%), Gaps = 43/404 (10%)
Query: 263 DEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKE 322
DE+ L ++ E ++R+ ++ ++L+E+ ++ SL G+ + L + +R KE
Sbjct: 427 DEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKE 486
Query: 323 V-----QLEARARKLRES--LKTGEVTTSQLIQQR-DSLQA-------------EVLECK 361
+ ++E K+ +S L+ T L Q+R DS Q E E
Sbjct: 487 IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELH 546
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIE 418
+Q+ + + + KS ++L++ +Q K ALQE E+ +R EL K++ +L+D +E
Sbjct: 547 KQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEME 606
Query: 419 ELQAKIIELEKSKPNPD-LPTEREIDL-WAELQATKETLRVTEDEVTTCKREKESENKIG 476
K+ + + + L E E L A +A+KE ++ E CK+ + +
Sbjct: 607 VATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKER-KLREHSENFCKQMESELEALK 665
Query: 477 IQQ--KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTIANC 533
++Q + A L ++ I K++ + E+KV+ Y E+ VR +H + N
Sbjct: 666 VKQGGRGAGATLEHQQEISKIKSEL----------EKKVLFYEEELVRREASHVLEVKNV 715
Query: 534 -QESPNGISYQ-DLQQEIMDLKMKL-LDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
+E + S+Q LQ+EI+ LK KL R+ E+ E + + E++ + +
Sbjct: 716 KKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKK 775
Query: 591 IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA 634
+ E + +K T Q+R+L QDL + V QIA
Sbjct: 776 LTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIA 819
Score = 59.3 bits (137), Expect = 5e-08
Identities = 84/386 (21%), Positives = 173/386 (44%), Gaps = 35/386 (9%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDE-----ERTAKLAIKEKLT 277
+E+ KL +++E I + L + E+T AL + R + + E+ ++ +EK
Sbjct: 485 KEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEK-E 543
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
QL + R+ K+L++A L ++ + Q + +R+LR+ +
Sbjct: 544 ELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEE 603
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
EV T Q+ D+++ E+ ++ ++L Q A+ + ++ R L+E E
Sbjct: 604 EMEVAT----QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKE-----RKLREHSENFC 654
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
+++E + Q R A L+ + E SK +L E+++ + E +E V
Sbjct: 655 KQMESELEALKVKQGGRGAGATLEH---QQEISKIKSEL--EKKVLFYEEELVRREASHV 709
Query: 458 TEDEVTTCKRE-KESEN-KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK--LNEQKV 513
E V K+E +SE+ ++ +Q+++ E+ + + E + IK ++
Sbjct: 710 LE--VKNVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERA 767
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK 573
+ +++ + L A N + + + + Q L+ E+ DL K V H +++EI+
Sbjct: 768 MLFDEN-KKLTAENEKLCSFVDKLTAQNRQ-LEDELQDLAAKKESVAHWEAQIAEII--- 822
Query: 574 DQELEQQDKNSRG--QARVIKIREEL 597
+ +K++RG QA K+ EEL
Sbjct: 823 --QWVSDEKDARGYLQALASKMTEEL 846
Score = 39.1 bits (87), Expect = 0.052
Identities = 37/151 (24%), Positives = 73/151 (48%), Gaps = 11/151 (7%)
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+K+ + Q V+ L +R ++N + L +EI LK K+ D +L + +
Sbjct: 459 RKLQESTQTVQSLHGSSRALSNSNRDKE---IKKLNEEIERLKNKIADSNRLERQLEDTV 515
Query: 571 AKKDQELEQQDKNSRG---QARVIKI-REELINVL---KNKETEQSRELAALQQDLEHRM 623
A + QE E + RG Q RV++ +EEL L + Q++EL Q + +
Sbjct: 516 ALR-QEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLAL 574
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ E+N+++A + Q++ L +K++++
Sbjct: 575 QEFSELNERMAELRAQKQKVSRQLRDKEEEM 605
>AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.
Length = 1760
Score = 69.3 bits (162), Expect = 4e-11
Identities = 99/404 (24%), Positives = 184/404 (45%), Gaps = 43/404 (10%)
Query: 263 DEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKE 322
DE+ L ++ E ++R+ ++ ++L+E+ ++ SL G+ + L + +R KE
Sbjct: 476 DEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKE 535
Query: 323 V-----QLEARARKLRES--LKTGEVTTSQLIQQR-DSLQA-------------EVLECK 361
+ ++E K+ +S L+ T L Q+R DS Q E E
Sbjct: 536 IKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELH 595
Query: 362 QQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIEL---KERTETELQDSRNAIE 418
+Q+ + + + KS ++L++ +Q K ALQE E+ +R EL K++ +L+D +E
Sbjct: 596 KQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEME 655
Query: 419 ELQAKIIELEKSKPNPD-LPTEREIDL-WAELQATKETLRVTEDEVTTCKREKESENKIG 476
K+ + + + L E E L A +A+KE ++ E CK+ + +
Sbjct: 656 VATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKER-KLREHSENFCKQMESELEALK 714
Query: 477 IQQ--KLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY-EQYVRDLQAHNRTIANC 533
++Q + A L ++ I K++ + E+KV+ Y E+ VR +H + N
Sbjct: 715 VKQGGRGAGATLEHQQEISKIKSEL----------EKKVLFYEEELVRREASHVLEVKNV 764
Query: 534 -QESPNGISYQ-DLQQEIMDLKMKL-LDVVHRNEELSEILAKKDQELEQQDKNSRGQARV 590
+E + S+Q LQ+EI+ LK KL R+ E+ E + + E++ + +
Sbjct: 765 KKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKK 824
Query: 591 IKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIA 634
+ E + +K T Q+R+L QDL + V QIA
Sbjct: 825 LTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIA 868
Score = 59.3 bits (137), Expect = 5e-08
Identities = 84/386 (21%), Positives = 173/386 (44%), Gaps = 35/386 (9%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDE-----ERTAKLAIKEKLT 277
+E+ KL +++E I + L + E+T AL + R + + E+ ++ +EK
Sbjct: 534 KEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEK-E 592
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
QL + R+ K+L++A L ++ + Q + +R+LR+ +
Sbjct: 593 ELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEE 652
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK 397
EV T Q+ D+++ E+ ++ ++L Q A+ + ++ R L+E E
Sbjct: 653 EMEVAT----QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKE-----RKLREHSENFC 703
Query: 398 REIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
+++E + Q R A L+ + E SK +L E+++ + E +E V
Sbjct: 704 KQMESELEALKVKQGGRGAGATLEH---QQEISKIKSEL--EKKVLFYEEELVRREASHV 758
Query: 458 TEDEVTTCKRE-KESEN-KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK--LNEQKV 513
E V K+E +SE+ ++ +Q+++ E+ + + E + IK ++
Sbjct: 759 LE--VKNVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERA 816
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK 573
+ +++ + L A N + + + + Q L+ E+ DL K V H +++EI+
Sbjct: 817 MLFDEN-KKLTAENEKLCSFVDKLTAQNRQ-LEDELQDLAAKKESVAHWEAQIAEII--- 871
Query: 574 DQELEQQDKNSRG--QARVIKIREEL 597
+ +K++RG QA K+ EEL
Sbjct: 872 --QWVSDEKDARGYLQALASKMTEEL 895
Score = 39.1 bits (87), Expect = 0.052
Identities = 37/151 (24%), Positives = 73/151 (48%), Gaps = 11/151 (7%)
Query: 511 QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEIL 570
+K+ + Q V+ L +R ++N + L +EI LK K+ D +L + +
Sbjct: 508 RKLQESTQTVQSLHGSSRALSNSNRDKE---IKKLNEEIERLKNKIADSNRLERQLEDTV 564
Query: 571 AKKDQELEQQDKNSRG---QARVIKI-REELINVL---KNKETEQSRELAALQQDLEHRM 623
A + QE E + RG Q RV++ +EEL L + Q++EL Q + +
Sbjct: 565 ALR-QEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLAL 623
Query: 624 RIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ E+N+++A + Q++ L +K++++
Sbjct: 624 QEFSELNERMAELRAQKQKVSRQLRDKEEEM 654
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 68.9 bits (161), Expect = 6e-11
Identities = 90/425 (21%), Positives = 194/425 (45%), Gaps = 33/425 (7%)
Query: 255 LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL------- 307
LEE ++ ++++ +L SQ + +AK+ KQLR+ EA +
Sbjct: 1515 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1574
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRES-LKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
GT++MLE Q +++LE ++R++ K E ++ + R S Q ++ + + Q+E+
Sbjct: 1575 AGTIQMLE----QAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1630
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE 426
+ K + + + +L+ L +Q + +R+ E ++R +L+ ++ + + Q +
Sbjct: 1631 -EYEDKQKVLREKRELEGKLATLSDQ--VNRRDFESEKRLRKDLKRTKALLADAQLMLDH 1687
Query: 427 LEKSKPN----PDLPTEREIDLWAELQATKETLRV-TEDEVTTCKREKESENKIGIQQKL 481
L+ S P+ L + E + A K + E E + + ++ K ++++L
Sbjct: 1688 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1747
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ---YVRDLQAHNRTIANCQESPN 538
+ K EI +++ ++ + +K ++ V Q + + DLQA AN ++
Sbjct: 1748 SRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE-ANKEKQEL 1806
Query: 539 GISYQDLQQEIMDLKMKLLD--VVHRNE-ELSEILAKKDQELEQ----QDKNSRGQARVI 591
Q LQ ++ L+ ++D +V R E ++ E+ + + E Q + SR + +
Sbjct: 1807 QEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1866
Query: 592 KIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
K+ EE +N+E EQ++ L +D + M + + + K E++ +LE
Sbjct: 1867 KLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1926
Query: 650 KQQQI 654
Q +
Sbjct: 1927 ANQSL 1931
Score = 56.4 bits (130), Expect = 3e-07
Identities = 59/293 (20%), Positives = 138/293 (47%), Gaps = 22/293 (7%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
RE+A+L+ +E + R E +E++ ++D+ AK A++E+L+ + +
Sbjct: 1696 REIAQLKNQLEESEFTCAAAVKARKAME--VEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1753
Query: 283 LRQTRNRVAKMDKQLRE---------AEAS--ITSLTGTVKMLEDQSRQKEVQLEARARK 331
+ +NR+ + + + E A+AS + + LE+ +++K+ +L+ + +
Sbjct: 1754 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQ-ELQEKLQA 1812
Query: 332 LRESLKTGEVT-TSQLIQQRDSLQAEVLECKQQIEKLTVQH-KSAIQQLEEDLKQTKRAL 389
L+ ++ E + + + R + LE + + E+ V+ +S +L+E++++
Sbjct: 1813 LQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEER 1872
Query: 390 QEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQ 449
++ RE E +R + +L+D++ + EL K E E S+ +L + E L A Q
Sbjct: 1873 DQRIAAENREKEQNKRLQRQLRDTKEEMGELARK--EAEASRKKHELEMDLE-SLEAANQ 1929
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL 502
+ + L++ + + E E + + L L ++++ K Q + +L
Sbjct: 1930 SLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSL---QDMVTKYQKRKNKL 1979
Score = 52.8 bits (121), Expect = 4e-06
Identities = 100/476 (21%), Positives = 220/476 (46%), Gaps = 46/476 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA-KLRQDVETRNVMIDEIRELR 246
EL+ ++ + +++L+ ER T + + L E A +LR + E++EL+
Sbjct: 1292 ELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAE--------KEMKELQ 1343
Query: 247 SESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
++ + K +E M E+ E R + A + + R K ++ +RE + +
Sbjct: 1344 TQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR---LKYERAVREVDFTKK 1400
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L + + +Q + QLE R L+ + + QL ++ L AE+ + K +E
Sbjct: 1401 RLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1460
Query: 366 KLTVQ-HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI 424
V+ H+ +Q D + ++ + Q E +RE +L+ + L ++ + ++L+ K
Sbjct: 1461 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE-KLQREKDMLLAEAFSLKQQLEEKD 1519
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+++ T++ + L AELQ + ++DE + K +K+ + L A+
Sbjct: 1520 MDIAGF-------TQKVVSLEAELQDISS--QESKDEASLAKVKKQLRD-------LEAK 1563
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQ-YVRDLQAHNRTI----ANCQESPN 538
+ ++EE + + Q T ++++ KL E ++ + Q + +++++ + + +CQ+
Sbjct: 1564 VKDQEEELDE-QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1622
Query: 539 GISYQDLQQEIMDLKMKLL----DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ Q L++E D K K+L ++ + LS+ + ++D E E++ + + + +
Sbjct: 1623 QMEVQ-LEEEYED-KQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLAD 1680
Query: 595 EEL-INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+L ++ LKN RE+A L+ LE K A EI++L +++
Sbjct: 1681 AQLMLDHLKN-SAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD 1735
Score = 39.9 bits (89), Expect = 0.030
Identities = 48/221 (21%), Positives = 96/221 (43%), Gaps = 18/221 (8%)
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
E+Q ++E +R ++E+ + + E K + +L N + + ++ T EL
Sbjct: 1261 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRL-----NSDRLESRISELTSELT--- 1312
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEE 565
+E+ + + D + R A + Y L++++ ++M++++ + R E
Sbjct: 1313 --DERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1370
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQS------RELAALQQD 618
++ + D E + K R V ++ L ++K E EQ R L LQ D
Sbjct: 1371 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1430
Query: 619 LEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
E R + ++ K+ E+Q+ LE +Q + H LEK
Sbjct: 1431 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1471
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372
protein.
Length = 3225
Score = 68.9 bits (161), Expect = 6e-11
Identities = 88/411 (21%), Positives = 191/411 (46%), Gaps = 29/411 (7%)
Query: 262 LDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT----SLTGTVKMLEDQ 317
++ T + ++E+L E + + ++ + + D QL++ + ++ + +K L+
Sbjct: 1 MEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLH 60
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
++ K L +++ T T Q +Q E + +IEK ++HK +Q+
Sbjct: 61 AKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEK--IKHK--LQE 116
Query: 378 LEEDLK----QTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPN 433
EE + Q +A EQ + E+E + +LQ+ I LQA++ + + ++
Sbjct: 117 KEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQ-AEQA 175
Query: 434 PDLPTEREIDLWAELQATKET-LRVTEDE----VTTCKREKESENKIGIQQKLAAELLNK 488
L + +++ E A ET +R+ EDE VT E E + K+ + Q+ E ++
Sbjct: 176 AQLSSMQQV--VREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEE--HE 231
Query: 489 EEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE 548
E ++G+ Q+ L + + EQ+ Q ++ ++A + T+ N E+ S L++
Sbjct: 232 ESLVGRAQV-VDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKM 290
Query: 549 IMDLKMKLLDVVHRNEELSEILAKKDQELE-QQDKNSR----GQARVIKIREELINVLKN 603
+++ + L + EE+ +L + +Q + Q + SR Q ++ E+ ++L
Sbjct: 291 ELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSL 350
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
++T Q + +A + +++ + N+Q A IQ+L L+ K ++I
Sbjct: 351 QKTGQELQ-SACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEI 400
Score = 68.1 bits (159), Expect = 1e-10
Identities = 117/525 (22%), Positives = 246/525 (46%), Gaps = 52/525 (9%)
Query: 147 ENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKR 206
E++ N V++D + D + + + DQ E L E K + ++ T+ +
Sbjct: 1779 ESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLEN---- 1834
Query: 207 ACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTK-ALEEMRHELDEE 265
E+ TL++ E+ L+++V N++ +I+E S K EE + +L+E
Sbjct: 1835 ---EKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER 1891
Query: 266 RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ---KE 322
+LA E + + + + A++ +L E+E + +L V LE++ +Q ++
Sbjct: 1892 LMNQLA--ELNGSIGNYCQDVTD--AQIKNELLESE--MKNLKKCVSELEEEKQQLVKEK 1945
Query: 323 VQLEARARK-LRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED 381
++E+ RK E ++ + ++ LQ E+L+ KQQ K + Q+
Sbjct: 1946 TKVESEIRKEYLEKIQGAQKEPGNKSHAKE-LQ-ELLKEKQQEVKQLQKDCIRYQEKISA 2003
Query: 382 LKQTKRALQEQCEITKREIEL-KERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
L++T +AL+ +++++E+ KE ++ + A EL + + L+ ++
Sbjct: 2004 LERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLAD 2063
Query: 441 EIDLWAELQATKETLR---VTEDEVTTCK----REKESENKIGIQQKLAA---ELLNKEE 490
+ L ELQ+ KE+++ +DE + EK + K +Q+KL A E ++ EE
Sbjct: 2064 NLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEE 2123
Query: 491 IIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIM 550
IG++Q+ + K ++ ++ + + V L A +++++ Q+ + + E
Sbjct: 2124 TIGEIQVTLNKKDKEVQQLQENL---DSTVTQLAAFTKSMSSLQDDRDRVI-----DEAK 2175
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR-EEL-INVLKNKETEQ 608
+ K D + EE EI K+D +D Q R + I EEL IN+ + + +Q
Sbjct: 2176 KWERKFSDAIQSKEE--EIRLKEDNCSVLKD-----QLRQMSIHMEELKINISRLEHDKQ 2228
Query: 609 SRELAALQQDLEHRMRIVDEV---NKQIAAKADEIQELFATLENK 650
E A Q +++ + ++ D + NK++ ++ +E + L+ + +N+
Sbjct: 2229 IWESKA-QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNE 2272
Score = 66.9 bits (156), Expect = 2e-10
Identities = 105/519 (20%), Positives = 227/519 (43%), Gaps = 49/519 (9%)
Query: 168 ILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAK 227
++E + D AL E + Q V ++ +++ ++ + + EA +
Sbjct: 690 LIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLD 749
Query: 228 LRQDVETRNVMIDEIRELRSESENTKA-LEEMRHELD-------EERTAKLAIKEKLTTT 279
N++ ++I L E+++ +E +++ELD E+ T +++ +L
Sbjct: 750 YESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNK 809
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRE-SLKT 338
ES++ + RV + ++ E +++ + ++ +K+ +E + + E +
Sbjct: 810 ESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV 869
Query: 339 GEVTTS------QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEED------LKQTK 386
E++ S QL +++ SL E+ K+Q+ L+ ++ +Q+EED LKQ
Sbjct: 870 TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNY 929
Query: 387 RALQEQCEITKREIE-----LKERTETELQDSRNAI---EELQAKIIELEKSKPNPDLPT 438
+ +I+K E++ LK+ E + + A+ +EL ++ LE+ N +
Sbjct: 930 DEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDES 989
Query: 439 EREIDL----WAELQATKETLRVTEDEVTTCKREKE-------SENKIGIQ--QKLAAEL 485
++EI L E++ KE +E VT+ +E E SE ++ +Q +K E
Sbjct: 990 KKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEK 1049
Query: 486 LNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQD 544
L EE + Q + +++ K N+ ++Q E + + QA + I + ++ +G S
Sbjct: 1050 LAAEEQFQALVKQMNQTLQD-KTNQIDLLQAE--ISENQAIIQKLITSNTDASDGDSVAL 1106
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK 604
+++ ++ H EL E + ++E EQ K + + R+ ++ + K
Sbjct: 1107 VKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQ---EALTSRKAILKKAQEK 1163
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
E EL + D DE +K+ D++++L
Sbjct: 1164 ERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1202
Score = 66.9 bits (156), Expect = 2e-10
Identities = 129/633 (20%), Positives = 280/633 (44%), Gaps = 57/633 (9%)
Query: 70 ELDRQAVLEVFQNLKSLYERLNNEGISACGE-GFLPQELILFNVADWTAQEVAQLYRDAI 128
E ++Q E Q L++ L ++ + GE L +E+ N+ + QE +L R
Sbjct: 1819 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQE--ELSRVTK 1876
Query: 129 ASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRE 188
T E + L+E + + + + + QD TD I L + + C + E
Sbjct: 1877 LKETAEEEKDDLEERL-MNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKC--VSE 1933
Query: 189 LKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSE 248
L+ + + V T + R+ + + +E E + ++ ++ +E++
Sbjct: 1934 LEEEKQQLVKEKTKVESEI---RKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL 1990
Query: 249 SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLT 308
++ +E L ERT K A++ T ++ L T+ +A+ + ++A+A + S
Sbjct: 1991 QKDCIRYQEKISAL--ERTVK-ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASF- 2046
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTG-EVTTSQLIQQRDSLQA--EVLECKQQIE 365
K+L D ++ + ++ A KL++ L++ E SQ+ Q+ + L+ E E K E
Sbjct: 2047 ---KVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKE 2103
Query: 366 KLTVQHK-SAIQQ----LEEDL--------KQTKRA--LQEQCEITKREIELKERTETEL 410
K +Q K A+++ LEE + K+ K LQE + T ++ ++ + L
Sbjct: 2104 KKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL 2163
Query: 411 QDSRNAI----EELQAKIIELEKSKPNPDLPTEREI----DLWAELQATKETLRVTEDEV 462
QD R+ + ++ + K + +SK E D ++ E L++ +
Sbjct: 2164 QDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRL 2223
Query: 463 TTCKR--EKESENKIGIQQKLAAELLNK-EEIIGKMQIQTRELIKNIKLNEQKVIQYEQY 519
K+ E +++ ++ +QQK+ L + +E++ +++ +TR L + + K+ +
Sbjct: 2224 EHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLE-ETRHLYHSSQNELAKLESELKS 2282
Query: 520 VRD-LQAHNRTIANCQESPNGISYQDLQQE--IMDLKMKLLDVVHRNEELSEILAKKDQE 576
++D L + ++ C+E + QQE I + K + + E+ ++ +E
Sbjct: 2283 LKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEE 2342
Query: 577 LEQQDKNSRGQARVIKIREELINV----LKNKETEQSRELAALQQDLEHRMRIVDEVNKQ 632
+ +++ ++ +EE I V L+ + ++ +EL L E +++E NK+
Sbjct: 2343 INMKEQKI---ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2399
Query: 633 IAAKADEIQELFATLENKQ-QQIHRLEKIVLAL 664
K +++ E T++ + QQ +L+ V ++
Sbjct: 2400 AVDKTNQLMETLKTIKKENIQQKAQLDSFVKSM 2432
Score = 66.9 bits (156), Expect = 2e-10
Identities = 107/526 (20%), Positives = 218/526 (41%), Gaps = 36/526 (6%)
Query: 161 QDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEA 220
+ Q D +I E L Q E L E +A D N + + K E A ++
Sbjct: 2369 RQQHDKEIKE-LENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDS 2427
Query: 221 LVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTE 280
V+ ++ L+ D R+ ++ + ++L E + + E + E +KE++
Sbjct: 2428 FVKSMSSLQND---RDRIVGDYQQL--EERHLSIILEKDQLIQEAAAENNKLKEEIRGLR 2482
Query: 281 SQLRQTRNRVAKMDKQL----REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
S + + AK+D +L + IT K L + Q+ +LE + KL E L
Sbjct: 2483 SHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKL 2542
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ-TKRALQEQCEI 395
K E L + ++LQ E + ++IE L V +Q+ ++ T Q ++
Sbjct: 2543 KESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKV 2602
Query: 396 TKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETL 455
+ E+ R S+ I EL+ +++ ++K E E L EL+
Sbjct: 2603 KEEEV---HRLSALFSSSQKRIAELEEELVCVQKEAAKK--VGEIEDKLKKELKHLHHDA 2657
Query: 456 RVTEDEVTTCKRE--KESENKIGIQQKLAAELLNKEEIIGKMQ--------IQTRELIKN 505
+ +E T + + + + + ++QKL + + ++Q +Q N
Sbjct: 2658 GIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHAN 2717
Query: 506 IKLNEQKVIQYEQYVRDL-QAHNRTIANCQE----SPNGISYQDLQQEIMDLKMKL-LDV 559
+L+E K +Y+ +++L Q + + N + S S ++ + KL +
Sbjct: 2718 EELDELK-RKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQL 2776
Query: 560 VHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVL-KNKETEQSRELAALQQD 618
+ ++E+L + ++ + Q S+ A + R+ L N L K +++E+ ++ +A Q
Sbjct: 2777 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPS 2836
Query: 619 LEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLAL 664
V + K +++ ++ L L+N QQQ ++ + + L
Sbjct: 2837 TSPAE--VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITEL 2880
Score = 62.9 bits (146), Expect = 4e-09
Identities = 87/456 (19%), Positives = 194/456 (42%), Gaps = 28/456 (6%)
Query: 219 EALVREVAKLRQD-VETRNVMIDEIRELRSESENT-KALEEMRHELDEERTAKLAIKEKL 276
E LV+E+ L+ + ++ +EL+ E E ++ E + +E + + A++++
Sbjct: 1550 EKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEK 1609
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
+LR T + +KQL+EAE + + ++ +QK ++LE +LR +
Sbjct: 1610 QELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEV 1669
Query: 337 KTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEIT 396
T + ++ S A + K+++E++ +++++ ++ + L K +L E+ +
Sbjct: 1670 HPAGDTAKECMETLLSSNASM---KEELERVKMEYETLSKKF-QSLMSEKDSLSEEVQDL 1725
Query: 397 KREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
K +IE + L+ + + Q + E E ++ P E++ + E++
Sbjct: 1726 KHQIEGNVSKQANLEATEK--HDNQTNVTE-EGTQSIPGETEEQDSLSMSTRPTCSESVP 1782
Query: 457 VTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+ ++ S ++I + +L KE I G + E KN + ++ +
Sbjct: 1783 SAKSANPAVSKDFSSHDEINNYLQQIDQL--KERIAGLEE----EKQKNKEFSQTLENEK 1836
Query: 517 EQYVRDLQAHNRTIANCQESPNGISY--QDLQQEIMDLKMKLLDVVHRNEELSEILAKKD 574
+ + + + QE ++ Q +Q+E+ + ++L E L +
Sbjct: 1837 NTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQL 1896
Query: 575 QELEQQDKNSRGQARVIKIREELI-NVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI 633
EL N +I+ EL+ + +KN + S QQ ++ + ++ E+ K+
Sbjct: 1897 AELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1956
Query: 634 AAKADEIQ----------ELFATLENKQQQIHRLEK 659
K Q EL L+ KQQ++ +L+K
Sbjct: 1957 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 1992
Score = 61.7 bits (143), Expect = 9e-09
Identities = 84/434 (19%), Positives = 187/434 (43%), Gaps = 19/434 (4%)
Query: 186 LRELKTQAEDAVNTV-TDLSKRACHERRTLIAVGEALVREVAKLRQDVETR-NVMIDEIR 243
+++ + E+ ++T+ LS+ + L ++ + + + A+ V + ++ +
Sbjct: 149 MKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVT 208
Query: 244 ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEAS 303
+ E+E + L ++ +L+E + + + + + +L R + +QL++ EA
Sbjct: 209 QADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAE 268
Query: 304 ITSLTGTVKMLEDQSR--QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECK 361
+L TV+ ++S+ ++++LE RKL S + L++Q + E +
Sbjct: 269 HNTLRNTVETEREESKILLEKMELEVAERKL--SFHNLQEEMHHLLEQFEQAGQAQAELE 326
Query: 362 QQIEKLTVQHKSAIQQLEE---DLKQTKRALQEQCEITKREIE--LKERTETELQDS--- 413
+ L +HK+ +++ L++T + LQ C+ K + L+++ E +Q +
Sbjct: 327 SRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTI 386
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKE-TLRVTEDEVTTC-KREKES 471
+ ++LQ K E+ + L + E T VTE+ + + KR E
Sbjct: 387 QQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVEL 446
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIA 531
EN+ G + EL + K+ Q L + E E + D+ N+ +
Sbjct: 447 ENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIA--NKRSS 504
Query: 532 NCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEI-LAKKDQELEQQDKNSRGQARV 590
+ +ES + Q+ +L + LL++ EE++ + L + + E+ D Q +
Sbjct: 505 SAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEM 564
Query: 591 IKIREELINVLKNK 604
++ E I +K K
Sbjct: 565 KQMEGEGIAPIKMK 578
Score = 57.6 bits (133), Expect = 1e-07
Identities = 90/451 (19%), Positives = 192/451 (42%), Gaps = 43/451 (9%)
Query: 241 EIRELRSESENTKAL-EEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
E +EL S+ E T+ L ++EL + + ++K++LT + L + + + ++ +R+
Sbjct: 2251 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ 2310
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQ-QRDSLQAEVL 358
EA I + + + LE Q +L +R L E + E L+ + +++Q +
Sbjct: 2311 QEADIQNSKFSYEQLETDL-QASRELTSR---LHEEINMKEQKIISLLSGKEEAIQVAIA 2366
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIE 418
E +QQ H I++LE L Q + E K+ ++ + L+ +
Sbjct: 2367 ELRQQ-------HDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENI 2419
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEV---TTCKREKESENKI 475
+ +A++ KS + +R + + +L+ ++ + +D++ + K E
Sbjct: 2420 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIR 2479
Query: 476 GIQQ----------KLAAELLNKEE----IIGKMQIQTRELIK-NIKLNEQKVIQYEQYV 520
G++ KL AEL+ E +I Q ++L++ ++ N++ +Y +
Sbjct: 2480 GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLE 2539
Query: 521 RDLQAHNRTIANCQESPNGI--SYQDLQQEIMDLKMKLLDVVHRNEELSE---------I 569
L+ + + S N + QDL +EI LK+ + + + L E
Sbjct: 2540 EKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQ 2599
Query: 570 LAKKDQELEQQDK-NSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDE 628
L K++E+ + S Q R+ ++ EEL+ V K + L+++L+H
Sbjct: 2600 LKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGI 2659
Query: 629 VNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ + + + EL L +Q++ + K
Sbjct: 2660 MRNETETAEERVAELARDLVEMEQKLLMVTK 2690
Score = 55.2 bits (127), Expect = 7e-07
Identities = 87/457 (19%), Positives = 196/457 (42%), Gaps = 31/457 (6%)
Query: 218 GEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLT 277
G V ++ +++E V + E++ + SE TK EE+ ++ L I+ T
Sbjct: 1266 GGTSVAQIKAQLKEIEAEKVEL-ELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKT 1324
Query: 278 TTESQLRQTRNRVAKMDK-QLREAEAS-ITSLTGTVKMLEDQSRQKEVQLEARARKLRES 335
+ + K++ QL+ A + L + L+ +KE + + +L E
Sbjct: 1325 VSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEK 1384
Query: 336 LKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE----------EDLKQT 385
+++I+Q D ++A Q+E +H I+QL+ E++ +
Sbjct: 1385 EAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEE 1440
Query: 386 KRALQE-----QCEITKREIELKER--TETELQDSRNAIEELQAKIIELEKSKPNPDLPT 438
RA Q+ Q + R+ LKE + EL +R IE L + ++E +
Sbjct: 1441 SRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEK 1500
Query: 439 EREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQ-I 497
+ + A LQ ++ L +TE + + + + S + ++ L +KE+++ +++ +
Sbjct: 1501 DTVLGRLALLQEERDKL-ITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESL 1559
Query: 498 QTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLL 557
++ ++ ++ + E+ ++Y LQ++ ++N E + + ++QE +L KL
Sbjct: 1560 KSSKIAESTEWQEKHKELQKEYEILLQSY-ENVSNEAERIQHV-VEAVRQEKQELYGKLR 1617
Query: 558 DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQ 617
+E + L + +QE+E+ + R + K +++ I L+ + E+
Sbjct: 1618 STEANKKETEKQLQEAEQEMEEMKEKMR---KFAKSKQQKILELEEENDRLRAEVHPAGD 1674
Query: 618 DLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ M + N + + + ++ + TL K Q +
Sbjct: 1675 TAKECMETLLSSNASMKEELERVKMEYETLSKKFQSL 1711
Score = 51.6 bits (118), Expect = 9e-06
Identities = 87/449 (19%), Positives = 203/449 (45%), Gaps = 38/449 (8%)
Query: 219 EALVREVAKLRQDVETR-NVMIDEIRELRSESENTK-ALEEMRHE---LDEERT-----A 268
E ++E + +D+ N + +E ++L E E+ K ++ ++ + L EE T A
Sbjct: 2539 EEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHA 2598
Query: 269 KLAIKEKLTTTESQL-RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEA 327
+L +KE+ S L ++ R+A+++++L + G + ED+ +++ L
Sbjct: 2599 QLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEI---EDKLKKELKHLHH 2655
Query: 328 RARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
A +R +T E ++L + ++ ++L ++ + LT Q +S + + L+ ++
Sbjct: 2656 DAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSS-LQNSRD 2714
Query: 388 ALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAE 447
E+ + KR+ + + +L++ E A + E S + + E + +
Sbjct: 2715 HANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTE---ENSLSHLEK 2771
Query: 448 LQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK 507
L ++ L E + + ++S N++ K A L N+ + + + + K+ +
Sbjct: 2772 LN--QQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWN---ELEKFRKSEE 2826
Query: 508 LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELS 567
++ Q ++Q+ + +++ Q + L +E+ +L+ + L + N+E++
Sbjct: 2827 GKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDR-----LLKELKNLQQQYLQI---NQEIT 2878
Query: 568 EILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR--- 624
E+ K Q E QDK Q ++R+E N+ E +Q R + + E RM+
Sbjct: 2879 ELHPLKAQLQEYQDKTKAFQIMQEELRQE--NLSWQHELDQLRMEKSSWEIHERRMKEQY 2936
Query: 625 --IVDEVNKQIAAKADEIQELFATLENKQ 651
+ + ++Q++ + I+EL ++ Q
Sbjct: 2937 LMAISDKDQQLSHLQNLIRELRSSSSQTQ 2965
Score = 48.0 bits (109), Expect = 1e-04
Identities = 87/413 (21%), Positives = 180/413 (43%), Gaps = 40/413 (9%)
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLR----QTRNRVAKMDKQLREAEASITSLT 308
K E+++ +L E T++ AI +K E LR Q ++ ++ +Q E ++
Sbjct: 1137 KEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1196
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAE-VLECKQQIEKL 367
++ L+ Q R+ + + + +ES + L + + + VLE +
Sbjct: 1197 DQLRQLQIQVRE-SIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWP 1255
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK-ERTETELQDSRNAIEELQAKIIE 426
+ ++ Q + Q K L+E E K E+ELK T +EL + +LQ +I
Sbjct: 1256 SHSEDASALQGGTSVAQIKAQLKE-IEAEKVELELKVSSTTSELTKKSEEVFQLQEQI-- 1312
Query: 427 LEKSKPNPDLPTEREIDLWAELQA--TKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+K ++ + + + AE+ A ++ L ++ ++ + +E + K+ QKL ++
Sbjct: 1313 ---NKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISK 1369
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQD 544
KEE + + Q E + + ++I+ E ++ L H + +E I +
Sbjct: 1370 ---KEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKAL--HTQLEMQAKEHDERI--KQ 1422
Query: 545 LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK 604
LQ E+ ++K K EE+ E + +Q + QA +I +E L +NK
Sbjct: 1423 LQVELCEMKQK-------PEEIGE------ESRAKQQIQRKLQAALISRKEAL---KENK 1466
Query: 605 ETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
++ EL+ + +E + + +V Q++A+ E + L Q++ +L
Sbjct: 1467 SLQE--ELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKL 1517
Score = 44.8 bits (101), Expect = 0.001
Identities = 91/431 (21%), Positives = 188/431 (43%), Gaps = 33/431 (7%)
Query: 250 ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLR--EAEASITSL 307
EN +L++ EL+ E+ A L +L +++ + +++ ++ Q R EA+ ++ +
Sbjct: 434 ENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEI 493
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE-- 365
+ + D + ++ E + + E+ T SQ ++ L E+ E +++I
Sbjct: 494 S-----IVDIANKRSSSAEESGQDVLEN------TFSQKHKELSVLLLEMKEAQEEIAFL 542
Query: 366 KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD-SRNAIEELQAKI 424
KL +Q K A + E L Q + E I I++K E QD EE
Sbjct: 543 KLQLQGKRAEEADHEVLDQKEMKQMEGEGIAP--IKMKVFLEDTGQDFPLMPNEESSLPA 600
Query: 425 IELEKSKPNPDLPTEREI---DLWAELQATKE----TLRVTEDEVTTCKREKESENKIGI 477
+E E++ T EI D EL++TK+ +L D + C +++ K I
Sbjct: 601 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPD-IGQCHQDELERLKSQI 659
Query: 478 QQKLAAELLNKEEIIGKMQIQTRELIKNI-KLNEQKVIQYEQYVRDLQAHNRTIANCQES 536
+ L +EI K + + I N+ +L E+ + A +
Sbjct: 660 LE-LELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQ 718
Query: 537 PNGISY-QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIRE 595
+S +L+ ++ L+M L + + E D L +Q + +A+ ++
Sbjct: 719 VKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKI 778
Query: 596 ELI-NVLKNKE---TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E++ N L + + +EQS + +LQ L+++ V E +++ + +++EL L K+
Sbjct: 779 EVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 838
Query: 652 QQIHRLEKIVL 662
+I ++++++L
Sbjct: 839 LEITKMDQLLL 849
Score = 44.8 bits (101), Expect = 0.001
Identities = 75/395 (18%), Positives = 158/395 (40%), Gaps = 20/395 (5%)
Query: 68 QPELDRQAVLEVFQNLKSLYERL-----NNEGISACGEGFLPQELILFNVADWTAQEVAQ 122
+ E + V E+ ++L + ++L N+G++A + F L N D +E+ +
Sbjct: 2663 ETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2722
Query: 123 LYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFEL 182
L R AS L L E + + + + T+ + L HL + N Q
Sbjct: 2723 LKRKYDASL---KELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSK 2779
Query: 183 CGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEI 242
L L +Q ED+ N V SK +L + L E+ K R+ E +
Sbjct: 2780 DEQLLHLSSQLEDSYNQVQSFSKAMA----SLQNERDHLWNELEKFRKSEEGKQ---RSA 2832
Query: 243 RELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
+ + ++L++ L +R L + L Q+ Q + + QL+E +
Sbjct: 2833 AQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQ- 2891
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQ 362
T ++++++ RQ+ + + +LR + E+ ++ +Q ++ +
Sbjct: 2892 ---DKTKAFQIMQEELRQENLSWQHELDQLRMEKSSWEIHERRMKEQYLMAISDKDQQLS 2948
Query: 363 QIEKLTVQHKSAIQQLEE-DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
++ L + +S+ Q + ++ ++A E L TE ++++E+
Sbjct: 2949 HLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIH 3008
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
K + +++ N E + L +L T ++LR
Sbjct: 3009 QKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLR 3043
Score = 40.3 bits (90), Expect = 0.023
Identities = 87/452 (19%), Positives = 194/452 (42%), Gaps = 37/452 (8%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKA----LEEMRHELDEER-TAKLAIKE 274
+L + V +L + + E+ EL++E+E + LE + +R ++++I +
Sbjct: 438 SLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVD 497
Query: 275 KLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRE 334
S ++ V + + E S+ L +M E Q ++L+ + ++ E
Sbjct: 498 IANKRSSSAEESGQDVLENTFSQKHKELSVLLL----EMKEAQEEIAFLKLQLQGKRAEE 553
Query: 335 SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK------LTVQHKSAIQQLEEDLKQTKRA 388
+ EV + ++Q + ++ K +E L +S++ +E++ T+
Sbjct: 554 A--DHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQ 611
Query: 389 LQEQCEITKRE--IELKERTETELQDSRNAIEEL-QAKIIELEKSKPNPDLPTEREIDLW 445
+ EI+ + +ELK T+ + S +A+ ++ Q ELE+ K E E++
Sbjct: 612 SRTSEEISLNDAGVELKS-TKQDGDKSLSAVPDIGQCHQDELERLKSQI---LELELNFH 667
Query: 446 AELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
+ ++ L E++ + E K A L++E ++ Q +EL
Sbjct: 668 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEER--DQLLSQVKELSMV 725
Query: 506 IKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
+L Q V Q E + + + R Q + + + + + ++ K K + + E
Sbjct: 726 TELRAQ-VKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNE 784
Query: 566 LSEI-LAKKDQELEQQDKNSRGQARVIKIRE--ELINVLKNKETEQSRELAALQQDLEHR 622
L ++ L +Q + S+ Q + ++ E E + + +K E S+ L+ Q++LE
Sbjct: 785 LDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS--QKELE-- 840
Query: 623 MRIVDEVNKQIAAKADEIQELFATLENKQQQI 654
+ ++++ + K +++ L T+E K QQ+
Sbjct: 841 ---ITKMDQLLLEKKRDVETLQQTIEEKDQQV 869
Score = 39.5 bits (88), Expect = 0.039
Identities = 88/469 (18%), Positives = 188/469 (40%), Gaps = 31/469 (6%)
Query: 210 ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE--LDEERT 267
E + L A ++ R ++ L+ + N +DE++ R + K L +++ + L+ ER
Sbjct: 2691 ENKGLTAQIQSFGRSMSSLQNSRDHANEELDELK--RKYDASLKELAQLKEQGLLNRERD 2748
Query: 268 AKLAIKE-KLTTTE----SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKE 322
A L+ + +TE S L + ++ D+QL + + V+ +
Sbjct: 2749 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQ 2808
Query: 323 VQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDL 382
+ + +L E + E + Q + AEV K+ + L +++L+
Sbjct: 2809 NERDHLWNEL-EKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQ 2867
Query: 383 KQTKRALQEQCEITKREIELKE---RTET-ELQDSRNAIEEL--QAKIIELEKSKPNPDL 436
+Q + QE E+ + +L+E +T+ ++ E L Q ++ +L K + ++
Sbjct: 2868 QQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELDQLRMEKSSWEI 2927
Query: 437 PTEREIDLWAELQATKET-LRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
R + + + K+ L ++ + + + +Q + A G
Sbjct: 2928 HERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQ 2987
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ--DLQQEIMDLK 553
+ + +LN+ +++ +R +Q N + E N +S Q D Q + + +
Sbjct: 2988 NLVYETELLRTQLNDSLKEIHQKELR-IQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQ 3046
Query: 554 MKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRE-- 611
D+++ +L K+ QEL+ N +E V + + E+ RE
Sbjct: 3047 QHYGDLLNH----CAVLEKQVQELQAGPLNIDVAPGA---PQEKNGVHRKSDPEELREPQ 3099
Query: 612 --LAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
+ QQ L + + V+E+ K + + D+ L ++QI RLE
Sbjct: 3100 QSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRLE 3148
>BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein.
Length = 790
Score = 68.9 bits (161), Expect = 6e-11
Identities = 104/510 (20%), Positives = 223/510 (43%), Gaps = 50/510 (9%)
Query: 170 EHLSRYNDQGFELCGALRELK---TQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
E L R + E+ L E++ + ED + ++++R E R L V E+
Sbjct: 256 ESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIK 315
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
L ++ +EI++ + ++E +E++H++DE + ++ K+ ++ T
Sbjct: 316 DLSDKLKVAEGKQEEIQQ-KGQAEK----KELQHKIDEMEEKEQELQAKIEALQADNDFT 370
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKML-EDQSRQKEVQLEARARKLRESLKTGEVTTSQ 345
R+ + ++L E +T K+ E+Q+R KE +E K+ + TT
Sbjct: 371 NERLTALQEKLI-VEGHLTKAVEETKLSKENQTRAKESDFSDTLSPSKE--KSSDDTTDA 427
Query: 346 LIQQRDSLQ--AEVLECKQQIE--KLTVQHKSAIQQLEEDLKQTKRALQEQCEITKRE-I 400
+ ++D + A+V K ++ + ++ K IQ L ++L + QE +K++
Sbjct: 428 QMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEA----QELARTSKQKCF 483
Query: 401 ELKERTETELQDSRNAIEEL--QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVT 458
EL+ E E + RN +EE Q ++++ + + + D RE + +E+ +T++ L
Sbjct: 484 ELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLRE-EKDSEITSTRDELLSA 542
Query: 459 EDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ 518
DE+ + K+A+E ++ I +Q + +++ ++ + +YE+
Sbjct: 543 RDEILLLHQAAA---------KVASE---RDTDIASLQEELKKVRAELERWRKAASEYEK 590
Query: 519 YVRDLQ-AHNRTIANCQESPNGIS------YQDLQQEIMDLKMKLLDVVHRNEELSEILA 571
+ LQ + C++ + + L++E L+ + + N LS L
Sbjct: 591 EITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQ 650
Query: 572 KKDQELEQQDKNSRGQARVIKI----REEL---INVLKNKETEQSRELAALQQDLEHRMR 624
++++EL K S + I R+EL + LK + S +L L E++ +
Sbjct: 651 RQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAK 710
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQI 654
V + ++ E++ F E ++Q I
Sbjct: 711 DVQKEYEKTQTVLSELKLKFEMTEQEKQSI 740
Score = 58.4 bits (135), Expect = 8e-08
Identities = 59/320 (18%), Positives = 146/320 (45%), Gaps = 14/320 (4%)
Query: 228 LRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEE----RTAKLAIKEKLTTTESQL 283
L + + +++ D+++ +SE E + ++ +R EL E RT+K E E +
Sbjct: 434 LNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEER 493
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
+ RN+V + KQ++ +A + L + L ++ + R+ +
Sbjct: 494 KAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAA 553
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC-EITKREIEL 402
+++ +RD+ A + E +++ + + A + E+++ + + Q +C + ++ E
Sbjct: 554 AKVASERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREE 613
Query: 403 KERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEV 462
R + EL+ R L+ + L++ N L +E + + K++L +T D
Sbjct: 614 ATRLQGELEKLRKEWNALETECHSLKRE--NVLLSSELQRQEKELHNSQKQSLELTSDLS 671
Query: 463 TTCKREKESENKIG-IQQKLAAELLNKEEIIGKMQIQTRELIKNIK-----LNEQKVIQY 516
KE EN++G ++++ + + + ++ K + Q +++ K + L+E K +++
Sbjct: 672 ILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSELK-LKF 730
Query: 517 EQYVRDLQAHNRTIANCQES 536
E ++ Q+ + C+ +
Sbjct: 731 EMTEQEKQSITDELKQCKNN 750
Score = 48.0 bits (109), Expect = 1e-04
Identities = 88/477 (18%), Positives = 202/477 (42%), Gaps = 35/477 (7%)
Query: 206 RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEI--RELRSESENTKALEEMRHELD 263
+AC + +T ++L +E+ L++D E R L+ + E + L E+ L
Sbjct: 225 QACSKNQT----EDSLRKELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLS 280
Query: 264 EERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEV 323
+KE T+ +LR+ N+ ++++ + G + ++ + + ++
Sbjct: 281 NTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKK 340
Query: 324 QLEARARKLRESLKTGEVTTS-QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDL 382
+L+ + ++ E K E+ + +Q + E L Q EKL V+ E L
Sbjct: 341 ELQHKIDEMEE--KEQELQAKIEALQADNDFTNERLTALQ--EKLIVEGHLTKAVEETKL 396
Query: 383 KQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREI 442
+ + ++ + + KE++ + D++ ++L + ++ K + + EI
Sbjct: 397 SKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQ-GAQSEI 455
Query: 443 DLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL 502
+ E+Q ++ L + E+ ++K E + ++++ A EE ++Q+ +L
Sbjct: 456 EAKQEIQHLRKEL-IEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQL 514
Query: 503 ----IKNIKLNEQKVIQYEQYVRD--LQAHNRTIANCQESPNGISYQD-----LQQEIMD 551
I L E+K + RD L A + + Q + S +D LQ+E+
Sbjct: 515 QRLHIDTENLREEKDSEITS-TRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKK 573
Query: 552 LKMKL----LDVVHRNEELSEI-----LAKKDQELEQQDKNSRGQARVIKIREELINVLK 602
++ +L +E++ + L + E +Q+++ +R Q + K+R+E N L+
Sbjct: 574 VRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEW-NALE 632
Query: 603 NKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ RE L +L+ + + + KQ ++ L + + + Q+ L++
Sbjct: 633 TECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKE 689
>BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein.
Length = 954
Score = 68.9 bits (161), Expect = 6e-11
Identities = 120/530 (22%), Positives = 226/530 (42%), Gaps = 67/530 (12%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNV--MIDEIR 243
+ +L ++ E + +T+ + A + ++ + E +++E A+ + + R + + +
Sbjct: 110 IEQLISEHEVEITGLTEKASSARSQANSIQSQME-IIQEQARNQNSMYMRQLSDLESTVS 168
Query: 244 ELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEAS 303
+LRSE K + E + E + E+ LA E LT ++ Q +D QL++ A
Sbjct: 169 QLRSELREAKRMYEDKTE-ELEKQLVLANSE-LTEARTERDQFSQESGNLDDQLQKLLAD 226
Query: 304 ITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE-VTTSQLIQQRDSLQAEVLECKQ 362
+ R+KE+ LE K TG +T L ++ D+ EV Q
Sbjct: 227 L------------HKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEV----Q 270
Query: 363 QIEKLTVQHKSAIQ-QLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
++E L KS Q Q+E + A+Q + E ++ L + E+ + R +EEL
Sbjct: 271 RLEALLKALKSECQGQMERQMA----AIQGKNESLEKVSSLTAQLESTKEMLRKVVEELT 326
Query: 422 AKIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
AK + LE S ER I DL LQ + + T E+T K + K+ Q
Sbjct: 327 AKKMTLESS--------ERTISDLTTSLQEKERAIEATNAEIT--KLRSRVDLKLQELQH 376
Query: 481 LAAE---LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
L E L N + +++Q E K I++ Q++ Q V H RT Q
Sbjct: 377 LKNEGDHLRNVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQ---HGRTAGAMQ--- 430
Query: 538 NGISYQDLQQEIMDLKMKLLDVV----HRNEELSEILAK-KDQELEQQDKNSRGQARVIK 592
+ L++EI D +M+L ++ ++ ++ E+ A+ D ELE+ + G R+
Sbjct: 431 --VEKAQLEKEINDRRMELKELKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRA 488
Query: 593 I------REELINVLKNKETE---QSRELAALQQDLEHRMR----IVDEVNKQIAAKADE 639
+ R++L+N +K +E S E L+++ ++ +++ Q+ + E
Sbjct: 489 VKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQLKSAQSE 548
Query: 640 IQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHEL 689
+++ TL++ + K+ + + KI LE +
Sbjct: 549 LEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAM 598
Score = 56.4 bits (130), Expect = 3e-07
Identities = 77/356 (21%), Positives = 164/356 (46%), Gaps = 21/356 (5%)
Query: 181 ELCGALRELKTQAEDAVNT-VTDLSKRA---CHERRTLIAVGEALVREVAKLRQDVETRN 236
+L +L+E K +A +A N +T L R E + L G+ L R V + ++ +
Sbjct: 341 DLTTSLQE-KERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL-RNVQTECEALKLQM 398
Query: 237 VMIDEIRE-LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMD 294
D++ E LR + EN T+ + + + K +++++ +L++ + K D
Sbjct: 399 TEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRMELKELKILKDKKD 458
Query: 295 KQLREAEASITSLT-GTVKMLEDQS-RQKEVQ-LEARARKLRESLKTGEVTTSQLIQQRD 351
++RE EA ++ L VK++ S R + V+ ++ +L +KT + L ++ +
Sbjct: 459 AKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRSELNNLSEEYE 518
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
L+ +++E T + K ++ + +L+QT+ L+ +++ + ++
Sbjct: 519 VLKRNFRNKSEEMEMTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQIT 578
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES 471
R I+ LQ+KI LE++ N + E+ L+ K L V T K +
Sbjct: 579 AKRGQIDALQSKIQFLEEAMTNAN--KEKHF-----LKEEKSKLSQELSTVATEKNKMAG 631
Query: 472 ENKI--GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYE-QYVRDLQ 524
E ++ +++L ++ N E + K +Q E I+ EQ+ ++ + Q+ D++
Sbjct: 632 ELEVLRSQERRLKEKVTNMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDIK 687
Score = 40.7 bits (91), Expect = 0.017
Identities = 43/213 (20%), Positives = 96/213 (45%), Gaps = 16/213 (7%)
Query: 179 GFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVE-TRNV 237
G E A++++K + + +N V K + E L E L R +++E T N
Sbjct: 482 GSERLRAVKDIKQERDQLLNEV----KTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNK 537
Query: 238 MIDEIRELRSESENTK-ALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRV------ 290
+ +++ +SE E T+ L+ M + +++++T Q+ ++++
Sbjct: 538 LKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEA 597
Query: 291 ---AKMDKQ-LREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
A +K L+E ++ ++ TV +++ + L ++ R+L+E + EV +
Sbjct: 598 MTNANKEKHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVTNMEVALDKA 657
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLE 379
Q Q + +Q+ +L +QH I++L+
Sbjct: 658 SLQFAECQDIIQRQEQESVRLKLQHTLDIKELQ 690
Score = 38.3 bits (85), Expect = 0.091
Identities = 73/400 (18%), Positives = 157/400 (39%), Gaps = 27/400 (6%)
Query: 273 KEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLT-GTVKMLEDQSRQKEVQLEARARK 331
++ L + +Q+ Q R + + L+E + + + K + + + +
Sbjct: 3 EDMLKDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKICEHDSMSTLHFRSLGSA 62
Query: 332 LRESLKTGEVTTSQL----IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKR 387
+ + L+ + S L D L+A E + +IE L QH+ I+QL + +
Sbjct: 63 ISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEIT 122
Query: 388 ALQEQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEK--SKPNPDLPTEREI-- 442
L E+ + + ++ + E + +RN ++ +LE S+ +L + +
Sbjct: 123 GLTEKASSARSQANSIQSQMEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYE 182
Query: 443 DLWAEL--QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTR 500
D EL Q +TE + +ES N QKL A+L +E+ + + Q +
Sbjct: 183 DKTEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNK 242
Query: 501 ELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVV 560
L N I + R+L N + + + + Q ++ ++ +
Sbjct: 243 RLWDRDTGNS---ITIDHLRRELDNRNMEVQRLEALLKALKSECQGQ----MERQMAAIQ 295
Query: 561 HRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLE 620
+NE L ++ L Q ++++ R K+ EEL E+ + R ++ L L+
Sbjct: 296 GKNESLEKV-----SSLTAQLESTKEMLR--KVVEELTAKKMTLESSE-RTISDLTTSLQ 347
Query: 621 HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
+ R ++ N +I + L++ + + L +
Sbjct: 348 EKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNV 387
>BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein.
Length = 1139
Score = 68.9 bits (161), Expect = 6e-11
Identities = 72/338 (21%), Positives = 159/338 (47%), Gaps = 24/338 (7%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-----LEEMRHELDEERTAKLAIKEKLTTTE 280
AKL++ +E + +++++E +S+ + +A L+E R E E AK E++ T
Sbjct: 109 AKLKE-LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 167
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+ +A +DK++ E A SL V+ L+++ + LE ++ E G
Sbjct: 168 DAIE-----MATLDKEMAEERAE--SLQQEVEALKERVDELTTDLEILKAEIEEKGSDGA 220
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI 400
++ QL +Q + A + + ++ L+ K +L++ +++ + L E+ +++
Sbjct: 221 ASSYQL-KQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL----EVVRQQ- 274
Query: 401 ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
+ER + EL + + I+EL+ ++ ++ ++ T+R ++L +++ +ET V +
Sbjct: 275 --RERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRET--VGDL 330
Query: 461 EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYV 520
E ++ EN + +L +L + + Q + + + +Q + +Y Q
Sbjct: 331 EAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLT 390
Query: 521 RDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD 558
+LQ NR + N QE+ + Q E D K+K +
Sbjct: 391 ANLQDVNRELTNQQEA-SVERQQQPPPETFDFKIKFAE 427
Score = 62.1 bits (144), Expect = 6e-09
Identities = 84/355 (23%), Positives = 159/355 (44%), Gaps = 32/355 (9%)
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
G V L S+++E L A+ R L E L+T +L + D + + LE K +I+
Sbjct: 71 GAVPPLPSPSKEEE-GLRAQVRDLEEKLET-----LRLKRAEDKAKLKELE-KHKIQLEQ 123
Query: 369 VQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
VQ KS +Q+ + DL+ R L+E + K +E KER E+ D+ +AIE + L
Sbjct: 124 VQEWKSKMQEQQADLQ---RRLKEARKEAKEALEAKERYMEEMADTADAIE-----MATL 175
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
+K ++ ER L E++A KE + ++ K E E + G + L
Sbjct: 176 DK-----EMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLE 230
Query: 488 KEEI-IGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQDL 545
++ + ++ R+L + K K+ + E+ ++L+ + QE
Sbjct: 231 EQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQE-----ELSQA 285
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
+ I +LK + +D EE+ E+L ++ LE++ + R ++ E+ + L+
Sbjct: 286 ESTIDELK-EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENA 344
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
E E L++ L+ V E K++ A + + + T++ +Q L+ +
Sbjct: 345 RETELE---LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTANLQDV 396
Score = 34.7 bits (76), Expect = 1.1
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 18/201 (8%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHER--RTLIAVGEALVREVAKLRQDVETRNVMI 239
L AL EL +A + + S C + LI+ L + + D E
Sbjct: 728 LVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTMNKLATAMQEGEYDAERPPSKP 787
Query: 240 D--EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL 297
E+R +E T A E + +L++ T +K+ L +L + R++ ++K+L
Sbjct: 788 PPVELRAAALRAEITDA-EGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKL 846
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
A K +++ + + +LE LR+ K E T L D L+AE
Sbjct: 847 DSA----------AKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEK 896
Query: 358 LECKQQIEKLTVQHKSAIQQL 378
E KQ +L Q K I+ L
Sbjct: 897 AELKQ---RLNSQSKRTIEGL 914
>BC012443-1|AAH12443.1| 717|Homo sapiens hook homolog 2
(Drosophila) protein.
Length = 717
Score = 68.9 bits (161), Expect = 6e-11
Identities = 80/286 (27%), Positives = 126/286 (44%), Gaps = 20/286 (6%)
Query: 184 GALRELKTQAEDAVNTVTDLSKR-ACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEI 242
G LREL+ Q V L +R A H RT E +R LR +E + + E+
Sbjct: 322 GELRELRRQ-------VRQLEERNAGHAERTRQLEDE--LRRAGSLRAQLEAQRRQVQEL 372
Query: 243 RELRSES--ENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
+ R E + K L E R+ L+E+ + KE+L LR+ + Q R
Sbjct: 373 QGQRQEEAMKAEKWLFECRN-LEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRGL 431
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLI--QQRDSLQAEVL 358
+ SL T +++ + + + E R LR L+ + + ++++ LQ ++
Sbjct: 432 TQADPSLDPTSTPVDNLAAEI-LPAELRETLLRLQLENKRLCRQEAADRERQEELQRQLE 490
Query: 359 ECKQQIEKLTVQHKSAIQQLEE---DLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
+ + L QH+ QQL E ++ ++ALQEQ T+ I LK + E LQ
Sbjct: 491 DANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDSILLKRKLEEHLQKLHE 550
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREI-DLWAELQATKETLRVTED 460
A ELQ K +E+ +P D T R I +L LQ LR E+
Sbjct: 551 ADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLRAMEE 596
Score = 49.6 bits (113), Expect = 4e-05
Identities = 89/408 (21%), Positives = 176/408 (43%), Gaps = 40/408 (9%)
Query: 239 IDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ----LRQTRNRVAKMD 294
+++++E E+ + E +R E A+L + + T+ +Q L+ + + +
Sbjct: 245 LEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQALKDEMDELRQSS 304
Query: 295 KQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
++ + EA++TS + L + RQ QLE R E + E +++ SL+
Sbjct: 305 ERAGQLEATLTSCRRRLGELRELRRQVR-QLEERNAGHAERTRQLE----DELRRAGSLR 359
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
A++ ++Q+++L Q + + E+ L + R L+E+ E +E KER E R
Sbjct: 360 AQLEAQRRQVQELQGQRQEEAMKAEKWLFEC-RNLEEKYESVTKE---KERLLAERDSLR 415
Query: 415 NAIEELQAKIIE---LEKSKPNPDLPTEREID------LWAELQATK-----ETLRVTED 460
A EEL+ ++ L ++ P+ D PT +D L AEL+ T E R+
Sbjct: 416 EANEELRCAQLQPRGLTQADPSLD-PTSTPVDNLAAEILPAELRETLLRLQLENKRLCRQ 474
Query: 461 EVTTCKREKESENKIGIQQKLAAEL-----LNKEEIIGKMQIQTRELIKNIKLNEQKVIQ 515
E +R++E + ++ + L LN++++ +++ Q +L K ++ K
Sbjct: 475 EAADRERQEELQRQLEDANRARHGLETQHRLNQQQL-SELRAQVEDLQKALQEQGGKTED 533
Query: 516 YEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL-LDVVHRNEELSEILAKKD 574
R L+ H + + + Q ++ I +L+ R EEL L KKD
Sbjct: 534 SILLKRKLEEHLQKLHEAD-----LELQRKREYIEELEPPTDSSTARRIEELQHNLQKKD 588
Query: 575 QELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
+L ++ R ++ + + + EL +L+ L R
Sbjct: 589 ADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRER 636
Score = 48.8 bits (111), Expect = 6e-05
Identities = 66/293 (22%), Positives = 129/293 (44%), Gaps = 23/293 (7%)
Query: 185 ALRELKTQAE---DAVNTVTDLSKRACHERRTLIAVGEAL--VREVAKLRQDVETRNVMI 239
AL L +A+ D ++ + S+RA TL + L +RE+ + + +E RN
Sbjct: 282 ALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNA-- 339
Query: 240 DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+E T+ LE+ R A + ++ + Q ++ + K + R
Sbjct: 340 -------GHAERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRN 392
Query: 300 AEASITSLTGTV-KMLEDQSRQKEVQLEARARKLR-ESLKTGEVTTSQLIQQRDSLQAEV 357
E S+T ++L ++ +E E R +L+ L + + D+L AE+
Sbjct: 393 LEEKYESVTKEKERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEI 452
Query: 358 L--ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
L E ++ + +L +++K +Q D ++ + LQ Q E R + ET+ + ++
Sbjct: 453 LPAELRETLLRLQLENKRLCRQEAAD-RERQEELQRQLEDANRA---RHGLETQHRLNQQ 508
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE 468
+ EL+A++ +L+K+ TE I L +L+ + L + E+ KRE
Sbjct: 509 QLSELRAQVEDLQKALQEQGGKTEDSILLKRKLEEHLQKLHEADLELQR-KRE 560
Score = 43.2 bits (97), Expect = 0.003
Identities = 96/441 (21%), Positives = 187/441 (42%), Gaps = 44/441 (9%)
Query: 247 SESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITS 306
S+S L E E DE + L ++ +L + + A + +++ E T
Sbjct: 172 SQSRRYYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPEGEGTP 231
Query: 307 LTGTVKMLEDQSRQKEVQLEA-RARKLRES--LKTGEVTTSQL-IQQRD----SLQAEVL 358
K+L QS+ +++Q E R RE L+ E+ +Q R+ SL E
Sbjct: 232 GLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQALTSLAQEAQ 291
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERT----------ET 408
K ++++L Q QLE L +R L E E+ ++ +L+ER E
Sbjct: 292 ALKDEMDELR-QSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQLED 350
Query: 409 ELQDS---RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTC 465
EL+ + R +E + ++ EL+ + + E+ + L+ E++ E E
Sbjct: 351 ELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESV-TKEKERLLA 409
Query: 466 KRE--KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDL 523
+R+ +E+ ++ Q L + + L I E + E +R L
Sbjct: 410 ERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELR----ETLLR-L 464
Query: 524 QAHNRTIANCQESPNGISYQDLQQEIMDLKMKL--LDVVHR--NEELSEILAKKDQELEQ 579
Q N+ + QE+ + ++LQ+++ D L+ HR ++LSE+ A+ ++L++
Sbjct: 465 QLENKRLCR-QEAADRERQEELQRQLEDANRARHGLETQHRLNQQQLSELRAQV-EDLQK 522
Query: 580 QDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQI-AAKAD 638
+ G+ E+ I +LK K E ++L +L+ + ++E+ ++ A
Sbjct: 523 ALQEQGGKT------EDSI-LLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTAR 575
Query: 639 EIQELFATLENKQQQIHRLEK 659
I+EL L+ K + +E+
Sbjct: 576 RIEELQHNLQKKDADLRAMEE 596
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 68.9 bits (161), Expect = 6e-11
Identities = 90/425 (21%), Positives = 194/425 (45%), Gaps = 33/425 (7%)
Query: 255 LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL------- 307
LEE ++ ++++ +L SQ + +AK+ KQLR+ EA +
Sbjct: 1044 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1103
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRES-LKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
GT++MLE Q +++LE ++R++ K E ++ + R S Q ++ + + Q+E+
Sbjct: 1104 AGTIQMLE----QAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1159
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE 426
+ K + + + +L+ L +Q + +R+ E ++R +L+ ++ + + Q +
Sbjct: 1160 -EYEDKQKVLREKRELEGKLATLSDQ--VNRRDFESEKRLRKDLKRTKALLADAQLMLDH 1216
Query: 427 LEKSKPN----PDLPTEREIDLWAELQATKETLRV-TEDEVTTCKREKESENKIGIQQKL 481
L+ S P+ L + E + A K + E E + + ++ K ++++L
Sbjct: 1217 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1276
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ---YVRDLQAHNRTIANCQESPN 538
+ K EI +++ ++ + +K ++ V Q + + DLQA AN ++
Sbjct: 1277 SRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE-ANKEKQEL 1335
Query: 539 GISYQDLQQEIMDLKMKLLD--VVHRNE-ELSEILAKKDQELEQ----QDKNSRGQARVI 591
Q LQ ++ L+ ++D +V R E ++ E+ + + E Q + SR + +
Sbjct: 1336 QEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1395
Query: 592 KIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
K+ EE +N+E EQ++ L +D + M + + + K E++ +LE
Sbjct: 1396 KLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1455
Query: 650 KQQQI 654
Q +
Sbjct: 1456 ANQSL 1460
Score = 56.0 bits (129), Expect = 4e-07
Identities = 46/230 (20%), Positives = 111/230 (48%), Gaps = 16/230 (6%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
RE+A+L+ +E + R E +E++ ++D+ AK A++E+L+ + +
Sbjct: 1225 REIAQLKNQLEESEFTCAAAVKARKAME--VEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1282
Query: 283 LRQTRNRVAKMDKQLRE---------AEAS--ITSLTGTVKMLEDQSRQKEVQLEARARK 331
+ +NR+ + + + E A+AS + + LE+ +++K+ +L+ + +
Sbjct: 1283 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQ-ELQEKLQA 1341
Query: 332 LRESLKTGEVT-TSQLIQQRDSLQAEVLECKQQIEKLTVQH-KSAIQQLEEDLKQTKRAL 389
L+ ++ E + + + R + LE + + E+ V+ +S +L+E++++
Sbjct: 1342 LQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEER 1401
Query: 390 QEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
++ RE E +R + +L+D++ + EL K E + K ++ E
Sbjct: 1402 DQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLE 1451
Score = 52.8 bits (121), Expect = 4e-06
Identities = 100/476 (21%), Positives = 220/476 (46%), Gaps = 46/476 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA-KLRQDVETRNVMIDEIRELR 246
EL+ ++ + +++L+ ER T + + L E A +LR + E++EL+
Sbjct: 821 ELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAE--------KEMKELQ 872
Query: 247 SESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
++ + K +E M E+ E R + A + + R K ++ +RE + +
Sbjct: 873 TQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR---LKYERAVREVDFTKK 929
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L + + +Q + QLE R L+ + + QL ++ L AE+ + K +E
Sbjct: 930 RLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 989
Query: 366 KLTVQ-HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI 424
V+ H+ +Q D + ++ + Q E +RE +L+ + L ++ + ++L+ K
Sbjct: 990 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE-KLQREKDMLLAEAFSLKQQLEEKD 1048
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+++ T++ + L AELQ + ++DE + K +K+ + L A+
Sbjct: 1049 MDIAGF-------TQKVVSLEAELQDISS--QESKDEASLAKVKKQLRD-------LEAK 1092
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQ-YVRDLQAHNRTI----ANCQESPN 538
+ ++EE + + Q T ++++ KL E ++ + Q + +++++ + + +CQ+
Sbjct: 1093 VKDQEEELDE-QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1151
Query: 539 GISYQDLQQEIMDLKMKLL----DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ Q L++E D K K+L ++ + LS+ + ++D E E++ + + + +
Sbjct: 1152 QMEVQ-LEEEYED-KQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLAD 1209
Query: 595 EEL-INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+L ++ LKN RE+A L+ LE K A EI++L +++
Sbjct: 1210 AQLMLDHLKN-SAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD 1264
Score = 39.9 bits (89), Expect = 0.030
Identities = 48/221 (21%), Positives = 96/221 (43%), Gaps = 18/221 (8%)
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
E+Q ++E +R ++E+ + + E K + +L N + + ++ T EL
Sbjct: 790 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRL-----NSDRLESRISELTSELT--- 841
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEE 565
+E+ + + D + R A + Y L++++ ++M++++ + R E
Sbjct: 842 --DERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 899
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQS------RELAALQQD 618
++ + D E + K R V ++ L ++K E EQ R L LQ D
Sbjct: 900 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 959
Query: 619 LEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
E R + ++ K+ E+Q+ LE +Q + H LEK
Sbjct: 960 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1000
Score = 38.7 bits (86), Expect = 0.069
Identities = 47/243 (19%), Positives = 104/243 (42%), Gaps = 20/243 (8%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
A + ++ + ED + D++K L + +L +D E N ++ + +
Sbjct: 1247 ARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKA 1306
Query: 245 LRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQ---LRQT---RNRVAKMDKQL 297
+++ A + +++ +L+E K ++EKL +SQ L Q+ ++ V++ + ++
Sbjct: 1307 AVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKI 1366
Query: 298 REAEASITSLTGTVKMLED-------------QSRQKEVQLEARARKLRESLKTGEVTTS 344
RE E + VK LE + R + + E R ++ + L+ T
Sbjct: 1367 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1426
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
+ + + +AE K ++E ++A Q L+ DLK + + + + E+E E
Sbjct: 1427 EEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1486
Query: 405 RTE 407
+
Sbjct: 1487 NED 1489
Score = 37.1 bits (82), Expect = 0.21
Identities = 38/161 (23%), Positives = 73/161 (45%), Gaps = 16/161 (9%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D+ L N + EL L+ L++Q E ++ D ++L++ EA +RE
Sbjct: 1320 DLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD---------KSLVSRQEAKIRE-- 1368
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
L +E + + L S + +E++ E D+ A+ KE+ + QLR T
Sbjct: 1369 -LETRLEFERTQVKRLESLASRLKEN--MEKLTEERDQRIAAENREKEQNKRLQRQLRDT 1425
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLE--DQSRQKEVQL 325
+ + ++ ++ EA L ++ LE +QS Q +++L
Sbjct: 1426 KEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKL 1466
>AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens
cDNA FLJ40198 fis, clone TESTI2019975, weakly similar to
TRICHOHYALIN. ).
Length = 621
Score = 68.9 bits (161), Expect = 6e-11
Identities = 93/481 (19%), Positives = 226/481 (46%), Gaps = 37/481 (7%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVG------EALVREVAKLRQDVET---R 235
A+++L+ +A D ++ + D K A + L AV + + E+ K R + R
Sbjct: 146 AVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYR 205
Query: 236 NVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKE---KLTTTESQL--RQTRNRV 290
N + DE EL+ + N K E+++ E+ +L +KE KL + L +Q +
Sbjct: 206 NTITDE--ELKEK--NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 261
Query: 291 AKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQR 350
+ K+L+ A + + ++ ++Q+E ++ + K++E ++ +Q
Sbjct: 262 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE-------WEEKIQEQE 314
Query: 351 DSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETEL 410
+ ++ + + ++Q EK+ Q + + + EE +++ + + E+ E +R E+ E ++
Sbjct: 315 EKIREQEEKIREQEEKMRRQ-EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 373
Query: 411 QDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKE 470
++ + E Q KI E E+ + + E+E E + ++ ++ E E ++EK+
Sbjct: 374 RELEEKMHE-QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 432
Query: 471 ---SENKIGIQQKLAAELLNKE-EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAH 526
E KI Q+K+ E +E E + + + + RE + I ++K+ + E+ + +
Sbjct: 433 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ-EEIWRQKEKMHEQEKIWKQEEKV 491
Query: 527 NRTIANCQESPNGISYQD-----LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQD 581
R + I Q+ +++I + + K+ + + E E + ++++++ +Q+
Sbjct: 492 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEEKIWEQE 551
Query: 582 KNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQ 641
+ R Q +++ +EE + + K EQ ++ ++ + + + E ++ + +++Q
Sbjct: 552 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 611
Query: 642 E 642
E
Sbjct: 612 E 612
Score = 57.6 bits (133), Expect = 1e-07
Identities = 93/416 (22%), Positives = 177/416 (42%), Gaps = 36/416 (8%)
Query: 264 EERTAKLA-IKEKLTTTESQLRQTRNRVAK--MDKQLREAEASITSLTGTVKMLEDQSRQ 320
E R +KLA KE+LT Q + A K++ T+ +G ED+ +
Sbjct: 48 ETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKA 107
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
EA R+L + T + T Q + LQ + + +++L + + I +L +
Sbjct: 108 SHQHQEALRRELEAQVHTIRILTCQ----KTELQMALYYSQHAVKQLEGEARDLISRLHD 163
Query: 381 DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTER 440
K L++ + + +R EL R+A+ +EL ++ + E+
Sbjct: 164 SWKFAGE-LEQALSAVATQKKKADRYIEELTKERDALS------LELYRNTITDEELKEK 216
Query: 441 EIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAEL--LNKE--EIIGKMQ 496
L +LQ + + V KR+ E + QQ+L AE L KE + K+Q
Sbjct: 217 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 276
Query: 497 IQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
Q E +LN+Q Q E+ R + QE I Q+ + + KM+
Sbjct: 277 AQVEENELWNRLNQQ---QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 333
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK--ETEQSRELAA 614
+ + +E E + ++++ + ++++ R ++ +EE I L+ K E E+ RE
Sbjct: 334 QEEMMWEKE--EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE 391
Query: 615 LQQDLEHRMRIVDEVNKQ----------IAAKADEIQELFATLENKQQQIHRLEKI 660
+Q+ E ++R ++ +Q I + ++I+E + ++++IH EKI
Sbjct: 392 KRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 446
Score = 52.8 bits (121), Expect = 4e-06
Identities = 40/193 (20%), Positives = 94/193 (48%), Gaps = 4/193 (2%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRE--LRSESENTKALEEMRHELDE--ERTAKLAIKE 274
E +RE K E + ++IRE R E E EE E +E + K+ +E
Sbjct: 423 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQE 482
Query: 275 KLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRE 334
K+ E ++ + ++ ++++RE E + ++ E++ R++E ++ + K+RE
Sbjct: 483 KIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIRE 542
Query: 335 SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
+ ++ +Q + +Q + + +Q EK+ Q + +Q E+ +Q ++ +++
Sbjct: 543 QEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 602
Query: 395 ITKREIELKERTE 407
+ ++E +++E E
Sbjct: 603 LRQQEEKMQEHQE 615
Score = 51.6 bits (118), Expect = 9e-06
Identities = 71/355 (20%), Positives = 165/355 (46%), Gaps = 26/355 (7%)
Query: 324 QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL----- 378
QLE AR L L +L Q ++ + + + IE+LT + + +L
Sbjct: 149 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI 208
Query: 379 -EEDLKQTKRALQEQCEIT---KREIELK-ERTETELQDSRNAI--EELQAKIIELEKSK 431
+E+LK+ LQE+ ++ K EI+L + + +L+ ++ + ++LQA+ L K
Sbjct: 209 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 268
Query: 432 PNPDLPTEREID---LWAELQATKETLRVTEDEVTTCKREK--ESENKIGIQQKLAAE-- 484
+ + +++ LW L +E ++E EK E E KI Q++ E
Sbjct: 269 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 328
Query: 485 --LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISY 542
+ +EE++ + + + R + + E+K+ + E+ + + + R + I
Sbjct: 329 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 388
Query: 543 QDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLK 602
Q+ +++ + K+ + R E+ +++ ++++ EQ++K + ++ + E++ K
Sbjct: 389 QEEKRQEEE---KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 445
Query: 603 NKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
+E E+ +E + + E ++R +E+ +Q K E ++++ E +Q ++
Sbjct: 446 IREEEKRQEQEEMWRQ-EEKIREQEEIWRQ-KEKMHEQEKIWKQEEKVWRQEEKM 498
Score = 50.0 bits (114), Expect = 3e-05
Identities = 83/393 (21%), Positives = 185/393 (47%), Gaps = 37/393 (9%)
Query: 274 EKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLR 333
E+LT L R D++L+E A + K+ +S + E+QL + +L+
Sbjct: 190 EELTKERDALSLELYRNTITDEELKEKNAKLQE-----KLQLVESEKSEIQLNVK--ELK 242
Query: 334 ESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC 393
L+ ++L+ + LQAE ++++ ++ + ++ Q+EE+ + R Q+Q
Sbjct: 243 RKLER-----AKLLLPQQQLQAEADHLGKELQSVSAKLQA---QVEEN-ELWNRLNQQQE 293
Query: 394 EITKREIELKERTETELQDSRNAIEELQAKIIELE-KSKPNPDLPTEREIDL--WAELQA 450
E R+ E + E ++Q+ I E + KI E E K + ++ E+E + E+
Sbjct: 294 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 353
Query: 451 TKETLRVTEDEVTTCKREK--ESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
KE +E+ K EK E E K+ Q+K+ + ++E K++ Q + + K+
Sbjct: 354 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE-EKIREQEKRQEQEAKM 412
Query: 509 --NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL 566
E+K+ + E+ +R+ + + + +E I Q+ +E + K + + + R EE
Sbjct: 413 WRQEEKIREQEEKIREQE---KKMWRQEEK---IHEQEKIRE--EEKRQEQEEMWRQEEK 464
Query: 567 SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIV 626
++ +E+ +Q + Q ++ K +EE + + K +Q ++ ++ + + +
Sbjct: 465 ----IREQEEIWRQKEKMHEQEKIWK-QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 519
Query: 627 DEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
E ++I + ++I+E + ++++I E+
Sbjct: 520 REQEEKIREQEEKIREQKEKIREQEEKIWEQEE 552
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 68.9 bits (161), Expect = 6e-11
Identities = 104/466 (22%), Positives = 199/466 (42%), Gaps = 51/466 (10%)
Query: 228 LRQDVETRNVMI-DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
L + + T N+ + D ++L+ + +ALEE + +E E+ +L +T
Sbjct: 12 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKT 71
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+NR+ + E + + L D RQ LE + RK + L + +S+
Sbjct: 72 KNRLQQ------ELDDLVVDL--------DNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 117
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE--------ITKR 398
+RD +AE E + + L + A+ + +E+L++T + L+ + E + K
Sbjct: 118 ADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLKAEMEDLVSSKDDVGKN 176
Query: 399 EIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD-----LPTEREIDLWAELQA 450
EL K ET++++ + +EEL+ ++ E +K + L + E DL A +
Sbjct: 177 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 236
Query: 451 TKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
+E R + ++ + E E E K ++KL +L + E E IK+
Sbjct: 237 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKH 296
Query: 506 IKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVH--- 561
++ + ++ +++ + D +A + A +E N + L+ ++M L+ L
Sbjct: 297 VRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEADLMQLQEDLAAAERARK 354
Query: 562 ----RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
EEL+E LA QD+ R +AR+ ++ EEL N E R A Q
Sbjct: 355 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 414
Query: 617 QDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEKIV 661
Q + + E + A K + Q+L + + ++H +E V
Sbjct: 415 QAEQLSNELATE--RSTAQKNESARQQLERQNKELRSKLHEMEGAV 458
Score = 52.0 bits (119), Expect = 7e-06
Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 16/208 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELD---EERTAKLAIKEKLTTTESQLRQ 285
++ +E R ++E EL E N +A+ + + E+ + +LA + RQ
Sbjct: 381 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 438
Query: 286 TRNRVAK-MDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R K + +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 439 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 493
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 494 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 550
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSK 431
+ + EL ++ + E + ++ L KSK
Sbjct: 551 RKLQRELDEATESNEAMGREVNAL-KSK 577
Score = 48.8 bits (111), Expect = 6e-05
Identities = 44/204 (21%), Positives = 96/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 323 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 377
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 378 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 433
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 434 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 493
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 494 LKQKDKKLKEILLQVEDERKMAEQ 517
Score = 35.5 bits (78), Expect = 0.64
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 13/184 (7%)
Query: 487 NKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
N E I + IQ + K ++ V E+ + Q + Q +Y L+
Sbjct: 11 NLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ-QYEEKAAAYDKLE 69
Query: 547 QEIMDLKMKLLDVV---HRNEELSEILAKKDQELEQ---QDKNSRGQARVIKIREELINV 600
+ L+ +L D+V +L L KK ++ +Q ++KN + + R E
Sbjct: 70 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA--E 127
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
+ KET+ AL++ LE + + + NK + A E+++L ++ ++ + +H LEK
Sbjct: 128 AREKETKALSLARALEEALEAKEEL-ERTNKMLKA---EMEDLVSSKDDVGKNVHELEKS 183
Query: 661 VLAL 664
AL
Sbjct: 184 KRAL 187
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 68.9 bits (161), Expect = 6e-11
Identities = 104/466 (22%), Positives = 199/466 (42%), Gaps = 51/466 (10%)
Query: 228 LRQDVETRNVMI-DEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
L + + T N+ + D ++L+ + +ALEE + +E E+ +L +T
Sbjct: 12 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKT 71
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
+NR+ + E + + L D RQ LE + RK + L + +S+
Sbjct: 72 KNRLQQ------ELDDLVVDL--------DNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 117
Query: 347 IQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE--------ITKR 398
+RD +AE E + + L + A+ + +E+L++T + L+ + E + K
Sbjct: 118 ADERDRAEAEAREKETKALSLARALEEAL-EAKEELERTNKMLKAEMEDLVSSKDDVGKN 176
Query: 399 EIEL---KERTETELQDSRNAIEELQAKIIELEKSKPNPD-----LPTEREIDLWAELQA 450
EL K ET++++ + +EEL+ ++ E +K + L + E DL A +
Sbjct: 177 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 236
Query: 451 TKETLRVTEDEVTTCKREKESENK-----IGIQQKLAAELLNKEEIIGKMQIQTRELIKN 505
+E R + ++ + E E E K ++KL +L + E E IK+
Sbjct: 237 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKH 296
Query: 506 IKLNEQKVIQYEQYVRDLQA-HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVH--- 561
++ + ++ +++ + D +A + A +E N + L+ ++M L+ L
Sbjct: 297 VRKLQAQMKDFQRELEDARASRDEIFATAKE--NEKKAKSLEADLMQLQEDLAAAERARK 354
Query: 562 ----RNEELSEILAKK-DQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
EEL+E LA QD+ R +AR+ ++ EEL N E R A Q
Sbjct: 355 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 414
Query: 617 QDLEHRMRIVDEVNKQIAAKADEI-QELFATLENKQQQIHRLEKIV 661
Q + + E + A K + Q+L + + ++H +E V
Sbjct: 415 QAEQLSNELATE--RSTAQKNESARQQLERQNKELRSKLHEMEGAV 458
Score = 52.8 bits (121), Expect = 4e-06
Identities = 53/216 (24%), Positives = 99/216 (45%), Gaps = 16/216 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELD---EERTAKLAIKEKLTTTESQLRQ 285
++ +E R ++E EL E N +A+ + + E+ + +LA + RQ
Sbjct: 381 KRRLEARIAQLEE--ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 438
Query: 286 TRNRVAK-MDKQLREAEASITS-LTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTT 343
R K + +L E E ++ S T+ LE + Q E Q+E AR+ + + K+
Sbjct: 439 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS----- 493
Query: 344 SQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
++Q+D E+L + K+ Q+K ++ +KQ KR L+E E ++R +
Sbjct: 494 ---LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 550
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
+ + EL ++ + E + ++ L KSK P E
Sbjct: 551 RKLQRELDEATESNEAMGREVNAL-KSKLRGPPPQE 585
Score = 48.8 bits (111), Expect = 6e-05
Identities = 44/204 (21%), Positives = 96/204 (47%), Gaps = 13/204 (6%)
Query: 220 ALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTT 279
A +E K + +E + + E +L + K + + EL EE + L+ + L
Sbjct: 323 ATAKENEKKAKSLEADLMQLQE--DLAAAERARKQADLEKEELAEELASSLSGRNAL--- 377
Query: 280 ESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTG 339
+ + R+ R+A+++++L E + ++ +++ V+ Q+ Q +L R + +
Sbjct: 378 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE----RSTAQKN 433
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEI 395
E QL +Q L++++ E + ++ K T+ A I QLEE ++Q R Q +
Sbjct: 434 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 493
Query: 396 TKREIELKERTETELQDSRNAIEE 419
K++ + + +++D R E+
Sbjct: 494 LKQKDKKLKEILLQVEDERKMAEQ 517
Score = 35.5 bits (78), Expect = 0.64
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 13/184 (7%)
Query: 487 NKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQ 546
N E I + IQ + K ++ V E+ + Q + Q +Y L+
Sbjct: 11 NLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ-QYEEKAAAYDKLE 69
Query: 547 QEIMDLKMKLLDVV---HRNEELSEILAKKDQELEQ---QDKNSRGQARVIKIREELINV 600
+ L+ +L D+V +L L KK ++ +Q ++KN + + R E
Sbjct: 70 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA--E 127
Query: 601 LKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
+ KET+ AL++ LE + + + NK + A E+++L ++ ++ + +H LEK
Sbjct: 128 AREKETKALSLARALEEALEAKEEL-ERTNKMLKA---EMEDLVSSKDDVGKNVHELEKS 183
Query: 661 VLAL 664
AL
Sbjct: 184 KRAL 187
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 68.9 bits (161), Expect = 6e-11
Identities = 90/425 (21%), Positives = 194/425 (45%), Gaps = 33/425 (7%)
Query: 255 LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL------- 307
LEE ++ ++++ +L SQ + +AK+ KQLR+ EA +
Sbjct: 1178 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1237
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRES-LKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
GT++MLE Q +++LE ++R++ K E ++ + R S Q ++ + + Q+E+
Sbjct: 1238 AGTIQMLE----QAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1293
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE 426
+ K + + + +L+ L +Q + +R+ E ++R +L+ ++ + + Q +
Sbjct: 1294 -EYEDKQKVLREKRELEGKLATLSDQ--VNRRDFESEKRLRKDLKRTKALLADAQLMLDH 1350
Query: 427 LEKSKPN----PDLPTEREIDLWAELQATKETLRV-TEDEVTTCKREKESENKIGIQQKL 481
L+ S P+ L + E + A K + E E + + ++ K ++++L
Sbjct: 1351 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1410
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ---YVRDLQAHNRTIANCQESPN 538
+ K EI +++ ++ + +K ++ V Q + + DLQA AN ++
Sbjct: 1411 SRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE-ANKEKQEL 1469
Query: 539 GISYQDLQQEIMDLKMKLLD--VVHRNE-ELSEILAKKDQELEQ----QDKNSRGQARVI 591
Q LQ ++ L+ ++D +V R E ++ E+ + + E Q + SR + +
Sbjct: 1470 QEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1529
Query: 592 KIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
K+ EE +N+E EQ++ L +D + M + + + K E++ +LE
Sbjct: 1530 KLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1589
Query: 650 KQQQI 654
Q +
Sbjct: 1590 ANQSL 1594
Score = 56.0 bits (129), Expect = 4e-07
Identities = 46/230 (20%), Positives = 111/230 (48%), Gaps = 16/230 (6%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
RE+A+L+ +E + R E +E++ ++D+ AK A++E+L+ + +
Sbjct: 1359 REIAQLKNQLEESEFTCAAAVKARKAME--VEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1416
Query: 283 LRQTRNRVAKMDKQLRE---------AEAS--ITSLTGTVKMLEDQSRQKEVQLEARARK 331
+ +NR+ + + + E A+AS + + LE+ +++K+ +L+ + +
Sbjct: 1417 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQ-ELQEKLQA 1475
Query: 332 LRESLKTGEVT-TSQLIQQRDSLQAEVLECKQQIEKLTVQH-KSAIQQLEEDLKQTKRAL 389
L+ ++ E + + + R + LE + + E+ V+ +S +L+E++++
Sbjct: 1476 LQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEER 1535
Query: 390 QEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE 439
++ RE E +R + +L+D++ + EL K E + K ++ E
Sbjct: 1536 DQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLE 1585
Score = 52.8 bits (121), Expect = 4e-06
Identities = 100/476 (21%), Positives = 220/476 (46%), Gaps = 46/476 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA-KLRQDVETRNVMIDEIRELR 246
EL+ ++ + +++L+ ER T + + L E A +LR + E++EL+
Sbjct: 955 ELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAE--------KEMKELQ 1006
Query: 247 SESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
++ + K +E M E+ E R + A + + R K ++ +RE + +
Sbjct: 1007 TQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR---LKYERAVREVDFTKK 1063
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L + + +Q + QLE R L+ + + QL ++ L AE+ + K +E
Sbjct: 1064 RLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1123
Query: 366 KLTVQ-HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI 424
V+ H+ +Q D + ++ + Q E +RE +L+ + L ++ + ++L+ K
Sbjct: 1124 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE-KLQREKDMLLAEAFSLKQQLEEKD 1182
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+++ T++ + L AELQ + ++DE + K +K+ + L A+
Sbjct: 1183 MDIAGF-------TQKVVSLEAELQDISS--QESKDEASLAKVKKQLRD-------LEAK 1226
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQ-YVRDLQAHNRTI----ANCQESPN 538
+ ++EE + + Q T ++++ KL E ++ + Q + +++++ + + +CQ+
Sbjct: 1227 VKDQEEELDE-QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1285
Query: 539 GISYQDLQQEIMDLKMKLL----DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ Q L++E D K K+L ++ + LS+ + ++D E E++ + + + +
Sbjct: 1286 QMEVQ-LEEEYED-KQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLAD 1343
Query: 595 EEL-INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+L ++ LKN RE+A L+ LE K A EI++L +++
Sbjct: 1344 AQLMLDHLKN-SAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD 1398
Score = 39.9 bits (89), Expect = 0.030
Identities = 48/221 (21%), Positives = 96/221 (43%), Gaps = 18/221 (8%)
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
E+Q ++E +R ++E+ + + E K + +L N + + ++ T EL
Sbjct: 924 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRL-----NSDRLESRISELTSELT--- 975
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEE 565
+E+ + + D + R A + Y L++++ ++M++++ + R E
Sbjct: 976 --DERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1033
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQS------RELAALQQD 618
++ + D E + K R V ++ L ++K E EQ R L LQ D
Sbjct: 1034 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1093
Query: 619 LEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
E R + ++ K+ E+Q+ LE +Q + H LEK
Sbjct: 1094 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1134
Score = 38.7 bits (86), Expect = 0.069
Identities = 47/243 (19%), Positives = 104/243 (42%), Gaps = 20/243 (8%)
Query: 185 ALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
A + ++ + ED + D++K L + +L +D E N ++ + +
Sbjct: 1381 ARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKA 1440
Query: 245 LRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQ---LRQT---RNRVAKMDKQL 297
+++ A + +++ +L+E K ++EKL +SQ L Q+ ++ V++ + ++
Sbjct: 1441 AVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKI 1500
Query: 298 REAEASITSLTGTVKMLED-------------QSRQKEVQLEARARKLRESLKTGEVTTS 344
RE E + VK LE + R + + E R ++ + L+ T
Sbjct: 1501 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1560
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKE 404
+ + + +AE K ++E ++A Q L+ DLK + + + + E+E E
Sbjct: 1561 EEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1620
Query: 405 RTE 407
+
Sbjct: 1621 NED 1623
Score = 37.1 bits (82), Expect = 0.21
Identities = 38/161 (23%), Positives = 73/161 (45%), Gaps = 16/161 (9%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D+ L N + EL L+ L++Q E ++ D ++L++ EA +RE
Sbjct: 1454 DLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD---------KSLVSRQEAKIRE-- 1502
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
L +E + + L S + +E++ E D+ A+ KE+ + QLR T
Sbjct: 1503 -LETRLEFERTQVKRLESLASRLKEN--MEKLTEERDQRIAAENREKEQNKRLQRQLRDT 1559
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLE--DQSRQKEVQL 325
+ + ++ ++ EA L ++ LE +QS Q +++L
Sbjct: 1560 KEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKL 1600
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 68.9 bits (161), Expect = 6e-11
Identities = 90/425 (21%), Positives = 194/425 (45%), Gaps = 33/425 (7%)
Query: 255 LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL------- 307
LEE ++ ++++ +L SQ + +AK+ KQLR+ EA +
Sbjct: 1494 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1553
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRES-LKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
GT++MLE Q +++LE ++R++ K E ++ + R S Q ++ + + Q+E+
Sbjct: 1554 AGTIQMLE----QAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1609
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIE 426
+ K + + + +L+ L +Q + +R+ E ++R +L+ ++ + + Q +
Sbjct: 1610 -EYEDKQKVLREKRELEGKLATLSDQ--VNRRDFESEKRLRKDLKRTKALLADAQLMLDH 1666
Query: 427 LEKSKPN----PDLPTEREIDLWAELQATKETLRV-TEDEVTTCKREKESENKIGIQQKL 481
L+ S P+ L + E + A K + E E + + ++ K ++++L
Sbjct: 1667 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1726
Query: 482 AAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQ---YVRDLQAHNRTIANCQESPN 538
+ K EI +++ ++ + +K ++ V Q + + DLQA AN ++
Sbjct: 1727 SRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE-ANKEKQEL 1785
Query: 539 GISYQDLQQEIMDLKMKLLD--VVHRNE-ELSEILAKKDQELEQ----QDKNSRGQARVI 591
Q LQ ++ L+ ++D +V R E ++ E+ + + E Q + SR + +
Sbjct: 1786 QEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1845
Query: 592 KIREELIN--VLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
K+ EE +N+E EQ++ L +D + M + + + K E++ +LE
Sbjct: 1846 KLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1905
Query: 650 KQQQI 654
Q +
Sbjct: 1906 ANQSL 1910
Score = 56.4 bits (130), Expect = 3e-07
Identities = 59/293 (20%), Positives = 138/293 (47%), Gaps = 22/293 (7%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQ 282
RE+A+L+ +E + R E +E++ ++D+ AK A++E+L+ + +
Sbjct: 1675 REIAQLKNQLEESEFTCAAAVKARKAME--VEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1732
Query: 283 LRQTRNRVAKMDKQLRE---------AEAS--ITSLTGTVKMLEDQSRQKEVQLEARARK 331
+ +NR+ + + + E A+AS + + LE+ +++K+ +L+ + +
Sbjct: 1733 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQ-ELQEKLQA 1791
Query: 332 LRESLKTGEVT-TSQLIQQRDSLQAEVLECKQQIEKLTVQH-KSAIQQLEEDLKQTKRAL 389
L+ ++ E + + + R + LE + + E+ V+ +S +L+E++++
Sbjct: 1792 LQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEER 1851
Query: 390 QEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQ 449
++ RE E +R + +L+D++ + EL K E E S+ +L + E L A Q
Sbjct: 1852 DQRIAAENREKEQNKRLQRQLRDTKEEMGELARK--EAEASRKKHELEMDLE-SLEAANQ 1908
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL 502
+ + L++ + + E E + + L L ++++ K Q + +L
Sbjct: 1909 SLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSL---QDMVTKYQKRKNKL 1958
Score = 52.8 bits (121), Expect = 4e-06
Identities = 100/476 (21%), Positives = 220/476 (46%), Gaps = 46/476 (9%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA-KLRQDVETRNVMIDEIRELR 246
EL+ ++ + +++L+ ER T + + L E A +LR + E++EL+
Sbjct: 1271 ELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAE--------KEMKELQ 1322
Query: 247 SESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
++ + K +E M E+ E R + A + + R K ++ +RE + +
Sbjct: 1323 TQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR---LKYERAVREVDFTKK 1379
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
L + + +Q + QLE R L+ + + QL ++ L AE+ + K +E
Sbjct: 1380 RLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLE 1439
Query: 366 KLTVQ-HKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKI 424
V+ H+ +Q D + ++ + Q E +RE +L+ + L ++ + ++L+ K
Sbjct: 1440 GQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE-KLQREKDMLLAEAFSLKQQLEEKD 1498
Query: 425 IELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAE 484
+++ T++ + L AELQ + ++DE + K +K+ + L A+
Sbjct: 1499 MDIAGF-------TQKVVSLEAELQDISS--QESKDEASLAKVKKQLRD-------LEAK 1542
Query: 485 LLNKEEIIGKMQIQTRELIKNIKLN-EQKVIQYEQ-YVRDLQAHNRTI----ANCQESPN 538
+ ++EE + + Q T ++++ KL E ++ + Q + +++++ + + +CQ+
Sbjct: 1543 VKDQEEELDE-QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1601
Query: 539 GISYQDLQQEIMDLKMKLL----DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ Q L++E D K K+L ++ + LS+ + ++D E E++ + + + +
Sbjct: 1602 QMEVQ-LEEEYED-KQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLAD 1659
Query: 595 EEL-INVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLEN 649
+L ++ LKN RE+A L+ LE K A EI++L +++
Sbjct: 1660 AQLMLDHLKN-SAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD 1714
Score = 39.9 bits (89), Expect = 0.030
Identities = 48/221 (21%), Positives = 96/221 (43%), Gaps = 18/221 (8%)
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNI 506
E+Q ++E +R ++E+ + + E K + +L N + + ++ T EL
Sbjct: 1240 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRL-----NSDRLESRISELTSELT--- 1291
Query: 507 KLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDV-VHRNEE 565
+E+ + + D + R A + Y L++++ ++M++++ + R E
Sbjct: 1292 --DERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1349
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQS------RELAALQQD 618
++ + D E + K R V ++ L ++K E EQ R L LQ D
Sbjct: 1350 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1409
Query: 619 LEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
E R + ++ K+ E+Q+ LE +Q + H LEK
Sbjct: 1410 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1450
>Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein.
Length = 4684
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2354 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2412
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2413 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2470
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2471 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2521
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2522 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2581
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2582 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2633
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2634 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2689
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2690 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2749
Query: 617 QDL 619
+++
Sbjct: 2750 EEV 2752
Score = 66.1 bits (154), Expect = 4e-10
Identities = 99/496 (19%), Positives = 210/496 (42%), Gaps = 48/496 (9%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1447 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1501
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L ++ E+ R++E ++A+ +K L
Sbjct: 1502 VEAALEKQRQLAEAHAQAKAQAEREAKELQQRIQ--EEVVRREEAAVDAQQQKRSIQEEL 1559
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1560 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1619
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQ 449
E+ E KR+ E ER ++QD + + ++ K++ +R + EL+
Sbjct: 1620 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1679
Query: 450 ATKETLRVTEDEVTTCKREKESENKIGI-----QQKLAAELLNKEEIIGKMQIQTRELIK 504
L+ E E C+ E E ++ + Q+ AEL +K + +T +L +
Sbjct: 1680 -----LQAEEAERWLCQAEVERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLER 1731
Query: 505 NIKLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHR 562
+++ V Q E+ R Q +E+ + L+ E + L+++ +V+ +
Sbjct: 1732 SLQEEHVAVAQLREEAERRAQQQAEAERAREEAERQLERWQLKANEALRLRLQAEEVLQQ 1791
Query: 563 NEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
+ L++ A+K +E +++ RG+A +R+ RELA +Q+LE +
Sbjct: 1792 -KSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQ 1834
Query: 623 MRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKI 682
++ + +Q A E+ L A E +QQ LE+ + L ++
Sbjct: 1835 RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAEL 1894
Query: 683 AALEHELAAGLNRKER 698
A + E+ L K +
Sbjct: 1895 AKVRAEMEVLLASKAK 1910
Score = 62.1 bits (144), Expect = 6e-09
Identities = 108/500 (21%), Positives = 218/500 (43%), Gaps = 41/500 (8%)
Query: 188 ELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRS 247
+L+ ++ V L + A ERR RE A+ + +E + +E LR
Sbjct: 1728 QLERSLQEEHVAVAQLREEA--ERRAQQQAEAERAREEAE--RQLERWQLKANEALRLRL 1783
Query: 248 ESENT---KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
++E K+L + E +E + A + + E +RQ +++KQ + AE +
Sbjct: 1784 QAEEVLQQKSLAQAEAEKQKEEAEREA-RRRGKAEEQAVRQRELAEQELEKQRQLAEGTA 1842
Query: 305 TSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQI 364
+ L + R + Q E + + L E L + + Q+R L+AE+ + + ++
Sbjct: 1843 QQRLAAEQELI-RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEM 1901
Query: 365 EKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETELQDSRN 415
E L A ++ +++K+ L+ + E+ + L+ + + +L +
Sbjct: 1902 EVLLASKAKAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1961
Query: 416 AIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTCKR--EK 469
A + +A+ + EK + L TE EI L E +A E L R+ EDE +R E+
Sbjct: 1962 ARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQRRRLEEQ 2020
Query: 470 ESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD 522
+++K I+++LA +EL ++ ++ Q R++ + I + + +
Sbjct: 2021 AAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 2080
Query: 523 LQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK---DQELE 578
L+ R +N +++ S + + E + + R E E + K ++E
Sbjct: 2081 LELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2138
Query: 579 QQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKA 637
+Q K + + +K + EE ++ + E E +R+L Q+ + R++ +E A +
Sbjct: 2139 RQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQ-AEEKAHAFAVQQ 2197
Query: 638 DEIQELFATLENKQQQIHRL 657
E QEL TL+ +Q + RL
Sbjct: 2198 KE-QELQQTLQQEQSVLDRL 2216
Score = 59.7 bits (138), Expect = 3e-08
Identities = 113/527 (21%), Positives = 220/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1610 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAEA 1662
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER A E+ + L +T R A + +L+
Sbjct: 1663 EAAREKQRALQALEELRLQAEEAERWLCQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1719
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E QL +R L+A E
Sbjct: 1720 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERQL--ERWQLKANE 1777
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1778 ALRLRLQAEEVLQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1835
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1836 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1886
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L K E+ E+ + L+A E
Sbjct: 1887 --RQELEAELA---KVRAEMEVL---LASKAKAEEESRSTSEKSKQRLEAEAGRFRELAE 1938
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1939 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1996
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1997 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 2054
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 2055 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 2101
Score = 57.6 bits (133), Expect = 1e-07
Identities = 87/438 (19%), Positives = 190/438 (43%), Gaps = 35/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMD--KQLR 298
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ + +Q +
Sbjct: 2084 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 2142
Query: 299 EAEASITSLTGTV---KMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
A + L V + L +++ Q+ QL+ ++ L+ E + +QQ++
Sbjct: 2143 AALEEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2202
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ L+ +Q + A ++ E+ ++ + + + ++R++E ER + ++
Sbjct: 2203 QQTLQQEQSVLDRLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA 2262
Query: 415 NAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKES 471
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2263 QARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTL 2315
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD--------L 523
K ++Q+L L EE + + EL + +K + + V + +
Sbjct: 2316 RQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQM 2374
Query: 524 QAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQ 580
+ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2375 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQL 2433
Query: 581 DKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAAK 636
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A +
Sbjct: 2434 AEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2493
Query: 637 -ADEIQELFATLENKQQQ 653
A+E Q TLE ++Q+
Sbjct: 2494 LAEETQGFQRTLEAERQR 2511
Score = 56.8 bits (131), Expect = 2e-07
Identities = 87/511 (17%), Positives = 211/511 (41%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1380 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1438
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1439 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1498
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q+I++ V+ + A + ++E+
Sbjct: 1499 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRIQEEVVRREEAAVDAQQQKRSIQEE 1558
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1559 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1617
Query: 442 IDLWAEL---QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE----EIIGK 494
AE QA +E R+ +R++++E ++ + K AE ++ + + +
Sbjct: 1618 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1677
Query: 495 MQIQTRELIK-----NIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEI 549
+++Q E + ++ Q + E R +A ++ + LQ+E
Sbjct: 1678 LRLQAEEAERWLCQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1737
Query: 550 MDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNK---ET 606
+ + + R ++ +E +++ Q ++ +++R + VL+ K +
Sbjct: 1738 VAVAQLREEAERRAQQQAEAERAREEAERQLERWQLKANEALRLRLQAEEVLQQKSLAQA 1797
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1798 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1857
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1858 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1888
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2514 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2573
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2574 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2632
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2633 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2692
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2693 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2749
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2750 -EEVTASQVAATKTLPN 2765
>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2244 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2302
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2303 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2360
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2361 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2411
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2412 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2471
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2472 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2523
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2524 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2579
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2580 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2639
Query: 617 QDL 619
+++
Sbjct: 2640 EEV 2642
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1337 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1391
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1392 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1449
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1450 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1509
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1510 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEELR 1569
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1570 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1623
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1624 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1682
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1683 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1726
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1727 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1786
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1787 VRAEMEVLLASKAR 1800
Score = 60.5 bits (140), Expect = 2e-08
Identities = 115/506 (22%), Positives = 218/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1607 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1665
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1666 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1725
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1726 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1785
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1786 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1845
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1846 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 1904
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 1905 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 1964
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 1965 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 2022
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K EE + + E E +R+L Q+ + R++ +E
Sbjct: 2023 AEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2081
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2082 AFAVQQKE-QELQQTLQQEQSVLDQL 2106
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1500 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAET 1552
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1553 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1609
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1610 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1667
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1668 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1725
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1726 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1776
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1777 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1828
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1829 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1886
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1887 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1944
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 1945 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1991
Score = 57.6 bits (133), Expect = 1e-07
Identities = 87/438 (19%), Positives = 189/438 (43%), Gaps = 35/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMD--KQLR 298
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ + +Q +
Sbjct: 1974 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 2032
Query: 299 EAEASITSLTGTV---KMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
A + L V + L +++ Q+ QL+ ++ L+ E + +QQ++
Sbjct: 2033 AALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2092
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ L+ +Q + A ++ E+ ++ + + + +R++E ER + ++
Sbjct: 2093 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAEEQA 2152
Query: 415 NAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKES 471
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2153 QARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTL 2205
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD--------L 523
K ++Q+L L EE + + EL + +K + + V + +
Sbjct: 2206 RQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQM 2264
Query: 524 QAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQ 580
+ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2265 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQL 2323
Query: 581 DKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAAK 636
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A +
Sbjct: 2324 AEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2383
Query: 637 -ADEIQELFATLENKQQQ 653
A+E Q TLE ++Q+
Sbjct: 2384 LAEETQGFQRTLEAERQR 2401
Score = 54.4 bits (125), Expect = 1e-06
Identities = 89/511 (17%), Positives = 206/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1270 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1328
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1329 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1388
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1389 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1448
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1449 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1507
Query: 442 IDLWAELQATK-----ETLRVTEDEVTTCKREKESE--NKIGIQQKLAAELLNKEEIIGK 494
AE Q + E LR + + KR+ E E +++ + + A E + + +
Sbjct: 1508 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEE 1567
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1568 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1627
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1628 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1687
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1688 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1747
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1748 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1778
Score = 52.8 bits (121), Expect = 4e-06
Identities = 86/464 (18%), Positives = 188/464 (40%), Gaps = 30/464 (6%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVET--RNVMIDEIRELRS 247
K +AE+ + ++ SK+ L E A+LR E R + E R
Sbjct: 1798 KARAEEESRSTSEKSKQRLEAEAGRF---RELAEEAARLRALAEEAKRQRQLAEEDAARQ 1854
Query: 248 ESENTKALEEMRHELDE----ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEAS 303
+E + L E + E + A++A+KEK E +LR+ A ++L E A
Sbjct: 1855 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE-RLRRLAEDEAFQRRRLEEQAAQ 1913
Query: 304 ITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ---AEVLEC 360
+ + L + + +LE + + ++L+ +++ + S + A E
Sbjct: 1914 HKA--DIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1971
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
+ ++ ++ + ++ E+ + R Q E +R E +ER + L A +
Sbjct: 1972 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2031
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+A + E+E+ K N + R + AE ++ ++ L++ ++ + +E + +QQK
Sbjct: 2032 KAALEEVERLKAN--VEEARRLRERAEQESARQ-LQLAQEAAQKRLQAEEKAHAFAVQQK 2088
Query: 481 ---LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
L L ++ ++ +++ + + + E+ +Q E+ + ++S
Sbjct: 2089 EQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSA 2148
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ Q + K+ R E E + E + A + K ++
Sbjct: 2149 EEQAQARAQAQAAAEKL-------RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2201
Query: 598 INVLKNK-ETEQSRELAALQ-QDLEHRMRIVDEVNKQIAAKADE 639
L+ K + EQ LQ ++ +H+ ++DE +++ A+A E
Sbjct: 2202 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2245
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2404 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2463
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2464 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2522
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2523 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2582
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2583 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2639
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2640 -EEVTASQVAATKTLPN 2655
>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2244 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2302
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2303 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2360
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2361 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2411
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2412 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2471
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2472 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2523
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2524 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2579
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2580 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2639
Query: 617 QDL 619
+++
Sbjct: 2640 EEV 2642
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1337 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1391
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1392 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1449
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1450 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1509
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1510 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEELR 1569
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1570 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1623
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1624 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1682
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1683 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1726
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1727 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1786
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1787 VRAEMEVLLASKAR 1800
Score = 60.5 bits (140), Expect = 2e-08
Identities = 115/506 (22%), Positives = 218/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1607 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1665
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1666 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1725
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1726 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1785
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1786 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1845
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1846 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 1904
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 1905 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 1964
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 1965 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 2022
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K EE + + E E +R+L Q+ + R++ +E
Sbjct: 2023 AEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2081
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2082 AFAVQQKE-QELQQTLQQEQSVLDQL 2106
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1500 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAET 1552
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1553 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1609
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1610 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1667
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1668 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1725
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1726 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1776
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1777 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1828
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1829 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1886
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1887 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1944
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 1945 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1991
Score = 57.6 bits (133), Expect = 1e-07
Identities = 87/438 (19%), Positives = 189/438 (43%), Gaps = 35/438 (7%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMD--KQLR 298
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ + +Q +
Sbjct: 1974 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 2032
Query: 299 EAEASITSLTGTV---KMLEDQSRQKEV-QLEARARKLRESLKTGEVTTSQLIQQRDSLQ 354
A + L V + L +++ Q+ QL+ ++ L+ E + +QQ++
Sbjct: 2033 AALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2092
Query: 355 AEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSR 414
+ L+ +Q + A ++ E+ ++ + + + +R++E ER + ++
Sbjct: 2093 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAEEQA 2152
Query: 415 NAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKES 471
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2153 QARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTL 2205
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD--------L 523
K ++Q+L L EE + + EL + +K + + V + +
Sbjct: 2206 RQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQM 2264
Query: 524 QAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQ 580
+ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2265 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQL 2323
Query: 581 DKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAAK 636
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A +
Sbjct: 2324 AEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ 2383
Query: 637 -ADEIQELFATLENKQQQ 653
A+E Q TLE ++Q+
Sbjct: 2384 LAEETQGFQRTLEAERQR 2401
Score = 54.4 bits (125), Expect = 1e-06
Identities = 89/511 (17%), Positives = 206/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1270 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1328
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1329 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1388
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1389 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1448
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1449 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1507
Query: 442 IDLWAELQATK-----ETLRVTEDEVTTCKREKESE--NKIGIQQKLAAELLNKEEIIGK 494
AE Q + E LR + + KR+ E E +++ + + A E + + +
Sbjct: 1508 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEE 1567
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1568 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1627
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1628 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1687
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1688 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1747
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1748 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1778
Score = 52.8 bits (121), Expect = 4e-06
Identities = 86/464 (18%), Positives = 188/464 (40%), Gaps = 30/464 (6%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVET--RNVMIDEIRELRS 247
K +AE+ + ++ SK+ L E A+LR E R + E R
Sbjct: 1798 KARAEEESRSTSEKSKQRLEAEAGRF---RELAEEAARLRALAEEAKRQRQLAEEDAARQ 1854
Query: 248 ESENTKALEEMRHELDE----ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEAS 303
+E + L E + E + A++A+KEK E +LR+ A ++L E A
Sbjct: 1855 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE-RLRRLAEDEAFQRRRLEEQAAQ 1913
Query: 304 ITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQ---AEVLEC 360
+ + L + + +LE + + ++L+ +++ + S + A E
Sbjct: 1914 HKA--DIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1971
Query: 361 KQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEEL 420
+ ++ ++ + ++ E+ + R Q E +R E +ER + L A +
Sbjct: 1972 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2031
Query: 421 QAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQK 480
+A + E+E+ K N + R + AE ++ ++ L++ ++ + +E + +QQK
Sbjct: 2032 KAALEEVERLKAN--VEEARRLRERAEQESARQ-LQLAQEAAQKRLQAEEKAHAFAVQQK 2088
Query: 481 ---LAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESP 537
L L ++ ++ +++ + + + E+ +Q E+ + ++S
Sbjct: 2089 EQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSA 2148
Query: 538 NGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREEL 597
+ Q + K+ R E E + E + A + K ++
Sbjct: 2149 EEQAQARAQAQAAAEKL-------RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2201
Query: 598 INVLKNK-ETEQSRELAALQ-QDLEHRMRIVDEVNKQIAAKADE 639
L+ K + EQ LQ ++ +H+ ++DE +++ A+A E
Sbjct: 2202 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATE 2245
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2404 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2463
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2464 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2522
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2523 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2582
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2583 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2639
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2640 -EEVTASQVAATKTLPN 2655
>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
Length = 4547
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2217 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2275
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2276 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2333
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2334 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2384
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2385 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2444
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2445 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2496
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2497 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2552
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2553 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2612
Query: 617 QDL 619
+++
Sbjct: 2613 EEV 2615
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1310 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1364
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1365 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1422
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1423 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1482
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1483 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1542
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1543 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1596
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1597 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1655
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1656 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1699
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1759
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1760 VRAEMEVLLASKAR 1773
Score = 61.3 bits (142), Expect = 1e-08
Identities = 115/506 (22%), Positives = 219/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1580 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1638
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1639 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1698
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1699 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1758
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1759 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1818
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1819 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 1877
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 1878 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 1937
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 1938 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1995
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K + EE + + E E +R+L Q+ + R++ +E
Sbjct: 1996 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2054
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2055 AFAVQQKE-QELQQTLQQEQSVLDQL 2079
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1473 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAEA 1525
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1526 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1582
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1583 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1640
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1641 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1698
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1699 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1749
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1750 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1801
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1802 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1859
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1860 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1917
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 1918 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1964
Score = 58.0 bits (134), Expect = 1e-07
Identities = 87/439 (19%), Positives = 192/439 (43%), Gaps = 37/439 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ ++ R+
Sbjct: 1947 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAE-EEAARQR 2004
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLR-------ESLKTGEVTTSQLIQQRDSL 353
+A++ + +E+ R +E + AR+L+ + L+ E + +QQ++
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2064
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ L+ +Q + A ++ E+ ++ + + + ++R++E ER + ++
Sbjct: 2065 LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2124
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKE 470
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2125 AQARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2177
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD-------- 522
K ++Q+L L EE + + EL + +K + + V +
Sbjct: 2178 LRQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQ 2236
Query: 523 LQAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
++ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2237 MEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQ 2295
Query: 580 QDKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAA 635
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A
Sbjct: 2296 LAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2355
Query: 636 K-ADEIQELFATLENKQQQ 653
+ A+E Q TLE ++Q+
Sbjct: 2356 QLAEETQGFQRTLEAERQR 2374
Score = 56.0 bits (129), Expect = 4e-07
Identities = 88/511 (17%), Positives = 208/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1243 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1301
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1302 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1361
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1421
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1422 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1480
Query: 442 IDLWAEL---QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE----EIIGK 494
AE QA +E R+ +R++++E ++ + K AE ++ + + +
Sbjct: 1481 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1540
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1541 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1600
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1601 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1660
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1661 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1720
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1751
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2377 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2436
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2437 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2495
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2496 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2555
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2556 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2612
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2613 -EEVTASQVAATKTLPN 2628
>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
Length = 4551
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2221 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2279
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2280 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2337
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2338 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2388
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2389 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2448
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2449 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2500
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2501 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2556
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2557 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2616
Query: 617 QDL 619
+++
Sbjct: 2617 EEV 2619
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1314 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1368
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1369 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1426
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1427 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1486
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1487 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1546
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1547 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1600
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1601 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1659
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1660 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1703
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1704 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1763
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1764 VRAEMEVLLASKAR 1777
Score = 61.3 bits (142), Expect = 1e-08
Identities = 115/506 (22%), Positives = 219/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1584 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1642
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1643 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1702
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1703 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1762
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1763 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1822
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1823 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 1881
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 1882 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 1941
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 1942 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1999
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K + EE + + E E +R+L Q+ + R++ +E
Sbjct: 2000 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2058
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2059 AFAVQQKE-QELQQTLQQEQSVLDQL 2083
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1477 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAEA 1529
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1530 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1586
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1587 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1644
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1645 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1702
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1703 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1753
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1754 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1805
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1806 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1863
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1864 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1921
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 1922 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1968
Score = 58.0 bits (134), Expect = 1e-07
Identities = 87/439 (19%), Positives = 192/439 (43%), Gaps = 37/439 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ ++ R+
Sbjct: 1951 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAE-EEAARQR 2008
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLR-------ESLKTGEVTTSQLIQQRDSL 353
+A++ + +E+ R +E + AR+L+ + L+ E + +QQ++
Sbjct: 2009 KAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2068
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ L+ +Q + A ++ E+ ++ + + + ++R++E ER + ++
Sbjct: 2069 LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2128
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKE 470
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2129 AQARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2181
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD-------- 522
K ++Q+L L EE + + EL + +K + + V +
Sbjct: 2182 LRQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQ 2240
Query: 523 LQAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
++ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2241 MEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQ 2299
Query: 580 QDKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAA 635
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A
Sbjct: 2300 LAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2359
Query: 636 K-ADEIQELFATLENKQQQ 653
+ A+E Q TLE ++Q+
Sbjct: 2360 QLAEETQGFQRTLEAERQR 2378
Score = 56.0 bits (129), Expect = 4e-07
Identities = 88/511 (17%), Positives = 208/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1247 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1305
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1306 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1365
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1366 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1425
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1426 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1484
Query: 442 IDLWAEL---QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE----EIIGK 494
AE QA +E R+ +R++++E ++ + K AE ++ + + +
Sbjct: 1485 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1544
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1545 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1604
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1605 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1664
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1665 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1724
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1725 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1755
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2381 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2440
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2441 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2499
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2500 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2559
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2560 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2616
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2617 -EEVTASQVAATKTLPN 2632
>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
Length = 4547
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2217 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2275
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2276 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2333
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2334 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2384
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2385 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2444
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2445 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2496
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2497 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2552
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2553 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2612
Query: 617 QDL 619
+++
Sbjct: 2613 EEV 2615
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1310 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1364
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1365 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1422
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1423 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1482
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1483 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1542
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1543 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1596
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1597 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1655
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1656 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1699
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1759
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1760 VRAEMEVLLASKAR 1773
Score = 61.3 bits (142), Expect = 1e-08
Identities = 115/506 (22%), Positives = 219/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1580 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1638
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1639 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1698
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1699 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1758
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1759 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1818
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1819 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 1877
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 1878 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 1937
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 1938 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1995
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K + EE + + E E +R+L Q+ + R++ +E
Sbjct: 1996 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2054
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2055 AFAVQQKE-QELQQTLQQEQSVLDQL 2079
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1473 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAEA 1525
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1526 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1582
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1583 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1640
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1641 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1698
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1699 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1749
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1750 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1801
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1802 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1859
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1860 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1917
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 1918 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1964
Score = 58.0 bits (134), Expect = 1e-07
Identities = 87/439 (19%), Positives = 192/439 (43%), Gaps = 37/439 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ ++ R+
Sbjct: 1947 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAE-EEAARQR 2004
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLR-------ESLKTGEVTTSQLIQQRDSL 353
+A++ + +E+ R +E + AR+L+ + L+ E + +QQ++
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2064
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ L+ +Q + A ++ E+ ++ + + + ++R++E ER + ++
Sbjct: 2065 LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2124
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKE 470
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2125 AQARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2177
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD-------- 522
K ++Q+L L EE + + EL + +K + + V +
Sbjct: 2178 LRQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQ 2236
Query: 523 LQAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
++ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2237 MEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQ 2295
Query: 580 QDKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAA 635
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A
Sbjct: 2296 LAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2355
Query: 636 K-ADEIQELFATLENKQQQ 653
+ A+E Q TLE ++Q+
Sbjct: 2356 QLAEETQGFQRTLEAERQR 2374
Score = 56.0 bits (129), Expect = 4e-07
Identities = 88/511 (17%), Positives = 208/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1243 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1301
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1302 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1361
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1421
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1422 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1480
Query: 442 IDLWAEL---QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE----EIIGK 494
AE QA +E R+ +R++++E ++ + K AE ++ + + +
Sbjct: 1481 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1540
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1541 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1600
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1601 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1660
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1661 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1720
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1721 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1751
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2377 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2436
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2437 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2495
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2496 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2555
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2556 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2612
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2613 -EEVTASQVAATKTLPN 2628
>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
Length = 4515
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2185 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2243
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2244 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2301
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2302 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2352
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2353 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2412
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2413 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2464
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2465 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2520
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2521 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2580
Query: 617 QDL 619
+++
Sbjct: 2581 EEV 2583
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1278 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1332
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1333 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1390
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1391 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1450
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1451 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1510
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1511 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1564
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1565 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1623
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1624 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1667
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1668 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1727
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1728 VRAEMEVLLASKAR 1741
Score = 61.3 bits (142), Expect = 1e-08
Identities = 115/506 (22%), Positives = 219/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1548 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1606
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1607 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1666
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1667 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1726
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1727 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1786
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1787 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 1845
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 1846 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 1905
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 1906 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1963
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K + EE + + E E +R+L Q+ + R++ +E
Sbjct: 1964 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2022
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2023 AFAVQQKE-QELQQTLQQEQSVLDQL 2047
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1441 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAEA 1493
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1494 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1550
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1551 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1608
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1609 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1666
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1667 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1717
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1718 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1769
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1770 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1827
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1828 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1885
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 1886 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1932
Score = 58.0 bits (134), Expect = 1e-07
Identities = 87/439 (19%), Positives = 192/439 (43%), Gaps = 37/439 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ ++ R+
Sbjct: 1915 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAE-EEAARQR 1972
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLR-------ESLKTGEVTTSQLIQQRDSL 353
+A++ + +E+ R +E + AR+L+ + L+ E + +QQ++
Sbjct: 1973 KAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2032
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ L+ +Q + A ++ E+ ++ + + + ++R++E ER + ++
Sbjct: 2033 LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2092
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKE 470
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2093 AQARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2145
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD-------- 522
K ++Q+L L EE + + EL + +K + + V +
Sbjct: 2146 LRQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQ 2204
Query: 523 LQAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
++ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2205 MEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQ 2263
Query: 580 QDKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAA 635
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A
Sbjct: 2264 LAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2323
Query: 636 K-ADEIQELFATLENKQQQ 653
+ A+E Q TLE ++Q+
Sbjct: 2324 QLAEETQGFQRTLEAERQR 2342
Score = 56.0 bits (129), Expect = 4e-07
Identities = 88/511 (17%), Positives = 208/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1211 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1269
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1270 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1329
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1330 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1389
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1390 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1448
Query: 442 IDLWAEL---QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE----EIIGK 494
AE QA +E R+ +R++++E ++ + K AE ++ + + +
Sbjct: 1449 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1508
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1509 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1568
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1569 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1628
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1629 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1688
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1689 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1719
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2345 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2404
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2405 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2463
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2464 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2523
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2524 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2580
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2581 -EEVTASQVAATKTLPN 2596
>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
Length = 4684
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2354 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2412
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2413 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2470
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2471 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2521
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2522 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2581
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2582 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2633
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2634 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2689
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2690 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2749
Query: 617 QDL 619
+++
Sbjct: 2750 EEV 2752
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1447 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1501
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1502 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1559
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1560 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1619
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1620 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1679
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1680 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1733
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1734 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1792
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1793 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1836
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1837 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1896
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1897 VRAEMEVLLASKAR 1910
Score = 61.3 bits (142), Expect = 1e-08
Identities = 115/506 (22%), Positives = 219/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1717 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1775
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1776 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1835
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1836 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1895
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1896 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1955
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1956 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 2014
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 2015 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 2074
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 2075 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 2132
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K + EE + + E E +R+L Q+ + R++ +E
Sbjct: 2133 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2191
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2192 AFAVQQKE-QELQQTLQQEQSVLDQL 2216
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1610 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAEA 1662
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1663 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1719
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1720 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1777
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1778 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1835
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1836 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1886
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1887 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1938
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1939 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1996
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1997 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 2054
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 2055 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 2101
Score = 58.0 bits (134), Expect = 1e-07
Identities = 87/439 (19%), Positives = 192/439 (43%), Gaps = 37/439 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ ++ R+
Sbjct: 2084 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAE-EEAARQR 2141
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLR-------ESLKTGEVTTSQLIQQRDSL 353
+A++ + +E+ R +E + AR+L+ + L+ E + +QQ++
Sbjct: 2142 KAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2201
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ L+ +Q + A ++ E+ ++ + + + ++R++E ER + ++
Sbjct: 2202 LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2261
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKE 470
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2262 AQARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2314
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD-------- 522
K ++Q+L L EE + + EL + +K + + V +
Sbjct: 2315 LRQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQ 2373
Query: 523 LQAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
++ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2374 MEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQ 2432
Query: 580 QDKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAA 635
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A
Sbjct: 2433 LAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2492
Query: 636 K-ADEIQELFATLENKQQQ 653
+ A+E Q TLE ++Q+
Sbjct: 2493 QLAEETQGFQRTLEAERQR 2511
Score = 56.0 bits (129), Expect = 4e-07
Identities = 88/511 (17%), Positives = 208/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1380 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1438
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1439 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1498
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1499 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1558
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1559 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1617
Query: 442 IDLWAEL---QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE----EIIGK 494
AE QA +E R+ +R++++E ++ + K AE ++ + + +
Sbjct: 1618 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1677
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1678 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1737
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1738 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1797
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1798 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1857
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1858 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1888
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2514 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2573
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2574 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2632
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2633 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2692
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2693 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2749
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2750 -EEVTASQVAATKTLPN 2765
>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
Length = 4525
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2195 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2253
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2254 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2311
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2312 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2362
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2363 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2422
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2423 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2474
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2475 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2530
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2531 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2590
Query: 617 QDL 619
+++
Sbjct: 2591 EEV 2593
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1288 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1342
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1343 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1400
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1401 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1460
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1461 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1520
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1521 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1574
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1575 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1633
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1634 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1677
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1678 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1737
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1738 VRAEMEVLLASKAR 1751
Score = 61.3 bits (142), Expect = 1e-08
Identities = 115/506 (22%), Positives = 219/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1558 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1616
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1617 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1676
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1677 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1736
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1737 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1796
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1797 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 1855
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 1856 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 1915
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 1916 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1973
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K + EE + + E E +R+L Q+ + R++ +E
Sbjct: 1974 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2032
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2033 AFAVQQKE-QELQQTLQQEQSVLDQL 2057
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1451 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAEA 1503
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1504 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1560
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1561 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1618
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1619 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1676
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1677 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1727
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1728 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1779
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1780 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1837
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1838 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1895
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 1896 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1942
Score = 58.0 bits (134), Expect = 1e-07
Identities = 87/439 (19%), Positives = 192/439 (43%), Gaps = 37/439 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ ++ R+
Sbjct: 1925 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAE-EEAARQR 1982
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLR-------ESLKTGEVTTSQLIQQRDSL 353
+A++ + +E+ R +E + AR+L+ + L+ E + +QQ++
Sbjct: 1983 KAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2042
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ L+ +Q + A ++ E+ ++ + + + ++R++E ER + ++
Sbjct: 2043 LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2102
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKE 470
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2103 AQARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2155
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD-------- 522
K ++Q+L L EE + + EL + +K + + V +
Sbjct: 2156 LRQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQ 2214
Query: 523 LQAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
++ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2215 MEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQ 2273
Query: 580 QDKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAA 635
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A
Sbjct: 2274 LAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2333
Query: 636 K-ADEIQELFATLENKQQQ 653
+ A+E Q TLE ++Q+
Sbjct: 2334 QLAEETQGFQRTLEAERQR 2352
Score = 56.0 bits (129), Expect = 4e-07
Identities = 88/511 (17%), Positives = 208/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1221 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1279
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1280 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1339
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1340 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1399
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1400 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1458
Query: 442 IDLWAEL---QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE----EIIGK 494
AE QA +E R+ +R++++E ++ + K AE ++ + + +
Sbjct: 1459 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1518
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1519 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1578
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1579 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1638
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1639 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1698
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1699 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1729
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2355 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2414
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2415 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2473
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2474 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2533
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2534 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2590
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2591 -EEVTASQVAATKTLPN 2606
>AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.
Length = 4533
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2203 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2261
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2262 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2319
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2320 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2370
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2371 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2430
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2431 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2482
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2483 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2538
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2539 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2598
Query: 617 QDL 619
+++
Sbjct: 2599 EEV 2601
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1296 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1350
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1351 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1408
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1409 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1468
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1469 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1528
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1529 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1582
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1583 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1641
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1642 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1685
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1686 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1745
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1746 VRAEMEVLLASKAR 1759
Score = 61.3 bits (142), Expect = 1e-08
Identities = 115/506 (22%), Positives = 219/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1566 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1624
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1625 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1684
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1685 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1744
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1745 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1804
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1805 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 1863
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 1864 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 1923
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 1924 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1981
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K + EE + + E E +R+L Q+ + R++ +E
Sbjct: 1982 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2040
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2041 AFAVQQKE-QELQQTLQQEQSVLDQL 2065
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1459 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAEA 1511
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1512 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1568
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1569 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1626
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1627 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1684
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1685 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1735
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1736 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1787
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1788 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1845
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1846 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1903
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 1904 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1950
Score = 58.0 bits (134), Expect = 1e-07
Identities = 87/439 (19%), Positives = 192/439 (43%), Gaps = 37/439 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ ++ R+
Sbjct: 1933 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAE-EEAARQR 1990
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLR-------ESLKTGEVTTSQLIQQRDSL 353
+A++ + +E+ R +E + AR+L+ + L+ E + +QQ++
Sbjct: 1991 KAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2050
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ L+ +Q + A ++ E+ ++ + + + ++R++E ER + ++
Sbjct: 2051 LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2110
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKE 470
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2111 AQARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2163
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD-------- 522
K ++Q+L L EE + + EL + +K + + V +
Sbjct: 2164 LRQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQ 2222
Query: 523 LQAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
++ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2223 MEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQ 2281
Query: 580 QDKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAA 635
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A
Sbjct: 2282 LAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2341
Query: 636 K-ADEIQELFATLENKQQQ 653
+ A+E Q TLE ++Q+
Sbjct: 2342 QLAEETQGFQRTLEAERQR 2360
Score = 56.0 bits (129), Expect = 4e-07
Identities = 88/511 (17%), Positives = 208/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1229 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1287
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1288 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1347
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1348 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1407
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1408 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1466
Query: 442 IDLWAEL---QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE----EIIGK 494
AE QA +E R+ +R++++E ++ + K AE ++ + + +
Sbjct: 1467 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1526
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1527 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1586
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1587 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1646
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1647 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1706
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1707 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1737
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2363 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2422
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2423 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2481
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2482 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2541
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2542 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2598
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2599 -EEVTASQVAATKTLPN 2614
>AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.
Length = 4574
Score = 68.5 bits (160), Expect = 7e-11
Identities = 92/423 (21%), Positives = 181/423 (42%), Gaps = 28/423 (6%)
Query: 201 TDLSKRACHERRTLIAVGEALVREVAKLRQDVETRN---VMIDEIRELRSESENTKALEE 257
T+ +++ L +V + E++KL+ +E N ++ D+ R E + +++
Sbjct: 2244 TEAARQRSQVEEELFSV-RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQ 2302
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
+ E A E L Q R KM K+ +A T L ++L+
Sbjct: 2303 VAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-- 2360
Query: 318 SRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQ 377
+QKE+ E +AR+L+E E QL ++ Q LE ++Q + ++ + ++
Sbjct: 2361 -QQKELAQE-QARRLQEDK---EQMAQQLAEETQGFQ-RTLEAERQRQ---LEMSAEAER 2411
Query: 378 LEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLP 437
L+ + + RA E +R + E +L + A +E + LE + D
Sbjct: 2412 LKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHD 2471
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
ER + AEL+ KE L+ E ++ K SE +QQ+ +LL + + + + +
Sbjct: 2472 AERLREAIAELEREKEKLQ-QEAKLLQLK----SEEMQTVQQE---QLLQETQALQQSFL 2523
Query: 498 QTRE-LIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
++ L++ + EQ+ + EQ +D A + + Q+ Q ++QE L +
Sbjct: 2524 SEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ----QQMEQERQRLVASM 2579
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+ R E E + +K +EL+Q ++ R Q ++ + + EQ R A
Sbjct: 2580 EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS 2639
Query: 617 QDL 619
+++
Sbjct: 2640 EEV 2642
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/494 (20%), Positives = 212/494 (42%), Gaps = 44/494 (8%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E++++E LR + + ++ SE + +EE +++R + +E+L
Sbjct: 1337 ESVIQEYVDLRTHYSELTTLTSQY--IKFISETLRRMEEEERLAEQQRAEE---RERLAE 1391
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK------L 332
E+ L + R + +AE L +M E+ R++E ++A+ +K L
Sbjct: 1392 VEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVVRREEAAVDAQQQKRSIQEEL 1449
Query: 333 RESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL--EEDLKQTKRALQ 390
++ ++ E +Q ++ + L +++I + +Q ++ +Q E Q RA
Sbjct: 1450 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARA 1509
Query: 391 EQCEITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL- 448
E+ E KR+ E ER ++QD + + ++ K++ +R + EL
Sbjct: 1510 EEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1569
Query: 449 -QATKETLRVTEDEVTTCKREKESENKIGIQQKLA-AELLNKEEIIGKMQIQTRELIKNI 506
QA + R+ + EV +R ++ + + Q+ A AEL +K + +T +L +++
Sbjct: 1570 LQAEEAERRLRQAEV---ERARQVQVALETAQRSAEAELQSKRASFAE---KTAQLERSL 1623
Query: 507 KLNEQKVIQY-EQYVRDLQAHNRTIANCQESPNGISYQDLQ-QEIMDLKMKLLDVVHRNE 564
+ V Q E+ R Q +E+ + L+ E + L+++ +V + +
Sbjct: 1624 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQ-K 1682
Query: 565 ELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMR 624
L++ A+K +E +++ RG+A +R+ RELA +Q+LE + +
Sbjct: 1683 SLAQAEAEKQKEEAEREARRRGKAEEQAVRQ--------------RELA--EQELEKQRQ 1726
Query: 625 IVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAA 684
+ + +Q A E+ L A E +QQ LE+ + L ++A
Sbjct: 1727 LAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK 1786
Query: 685 LEHELAAGLNRKER 698
+ E+ L K R
Sbjct: 1787 VRAEMEVLLASKAR 1800
Score = 61.3 bits (142), Expect = 1e-08
Identities = 115/506 (22%), Positives = 219/506 (43%), Gaps = 58/506 (11%)
Query: 204 SKRACHERRTLIAVGEALVRE---VAKLRQDVETRNVMIDEIRELRSESENT------KA 254
SKRA +T + +L E VA+LR++ E R E R E+E KA
Sbjct: 1607 SKRASFAEKTA-QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKA 1665
Query: 255 LEEMRHELDEERTAK---LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTV 311
E +R L E A+ LA E E R+ R R ++ +R+ E + L
Sbjct: 1666 NEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR 1725
Query: 312 KMLEDQSRQK---EVQL----------EARARKLRESLKTGEVTTSQLIQQRDSLQAEVL 358
++ E ++Q+ E +L E + + L E L + + Q+R L+AE+
Sbjct: 1726 QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELA 1785
Query: 359 ECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQC----EITKREIELK-----ERTETE 409
+ + ++E L A ++ +++K+ L+ + E+ + L+ + + +
Sbjct: 1786 KVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ 1845
Query: 410 LQDSRNAIEELQAKIIELEKSKPNPD---LPTEREIDLWAELQATKETL-RVTEDEVTTC 465
L + A + +A+ + EK + L TE EI L E +A E L R+ EDE
Sbjct: 1846 LAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL-KEKEAENERLRRLAEDEAFQR 1904
Query: 466 KR--EKESENKIGIQQKLA-------AELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQY 516
+R E+ +++K I+++LA +EL ++ ++ Q R++ + I + +
Sbjct: 1905 RRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKA 1964
Query: 517 EQYVRDLQAH-NRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKK-- 573
+L+ R +N +++ S + + E + + R E E + K
Sbjct: 1965 AAGKAELELELGRIRSNAEDTLR--SKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 2022
Query: 574 -DQELEQQDKNSRGQARVIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
++E +Q K + + +K + EE + + E E +R+L Q+ + R++ +E
Sbjct: 2023 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQ-AEEKAH 2081
Query: 632 QIAAKADEIQELFATLENKQQQIHRL 657
A + E QEL TL+ +Q + +L
Sbjct: 2082 AFAVQQKE-QELQQTLQQEQSVLDQL 2106
Score = 60.1 bits (139), Expect = 3e-08
Identities = 111/527 (21%), Positives = 221/527 (41%), Gaps = 47/527 (8%)
Query: 184 GALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEI 242
G L+ L+ +AE+A + KR E + + E + RQ +VE + + E
Sbjct: 1500 GELQALRARAEEA-----EAQKRQAQEEAERLR--RQVQDESQRKRQAEVELASRVKAEA 1552
Query: 243 RELRSESENTKALEEMRHELDE-ERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAE 301
R + +ALEE+R + +E ER + A E+ + L +T R A + +L+
Sbjct: 1553 EAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVAL-ETAQRSA--EAELQSKR 1609
Query: 302 ASITSLTGTV-KMLEDQS---RQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA-E 356
AS T + + L+++ Q + E RA++ E+ + E +L +R L+A E
Sbjct: 1610 ASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAEREL--ERWQLKANE 1667
Query: 357 VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNA 416
L + Q E++ Q A + E+ ++ +R + + + ++ + +E E EL+ R
Sbjct: 1668 ALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQR-- 1725
Query: 417 IEELQAKIIELEKSKPNPDLPTERE-IDLWAELQATKETLRVTEDEVTTCKREKESENKI 475
+L + L E+E I L AE + ++ ++ E+E+ +RE + +
Sbjct: 1726 ---------QLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQK 1776
Query: 476 GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQE 535
+Q+L AEL ++ +M++ L + E+ E+ + L+A E
Sbjct: 1777 --RQELEAELA---KVRAEMEVL---LASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1828
Query: 536 SPNGISYQDLQQEIM-DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIR 594
+ + L +E ++ D + E +LA+K + + + +K +
Sbjct: 1829 EAARL--RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEK 1886
Query: 595 E---ELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQ 651
E E + L E Q R L +Q +H+ I + + + A E++ +E+
Sbjct: 1887 EAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1944
Query: 652 QQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+Q ++E+ +LAL ++ + L KE+
Sbjct: 1945 RQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQ 1991
Score = 58.0 bits (134), Expect = 1e-07
Identities = 87/439 (19%), Positives = 192/439 (43%), Gaps = 37/439 (8%)
Query: 241 EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREA 300
E+ +RS +E+T +E EL+ R +LA +E+ E++ R ++ A+ ++ R+
Sbjct: 1974 ELGRIRSNAEDTLRSKEQA-ELEAARQRQLAAEEERRRREAEERVQKSLAAE-EEAARQR 2031
Query: 301 EASITSLTGTVKMLEDQSRQKEVQLEARARKLR-------ESLKTGEVTTSQLIQQRDSL 353
+A++ + +E+ R +E + AR+L+ + L+ E + +QQ++
Sbjct: 2032 KAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQE 2091
Query: 354 QAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDS 413
+ L+ +Q + A ++ E+ ++ + + + ++R++E ER + ++
Sbjct: 2092 LQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2151
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL-QATKETLRVTEDEVTTCKR--EKE 470
A + QA +L K E+E A+ QA + + E+ K+ E+
Sbjct: 2152 AQARAQAQAAAEKLRKE-------AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT 2204
Query: 471 SENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRD-------- 522
K ++Q+L L EE + + EL + +K + + V +
Sbjct: 2205 LRQKAQVEQELTTLRLQLEETDHQKNLLDEEL-QRLKAEATEAARQRSQVEEELFSVRVQ 2263
Query: 523 LQAHNRTIANCQESPNGISYQD---LQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQ 579
++ ++ A + + +D Q+ + + K+ V LS + A++ L Q
Sbjct: 2264 MEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS-VAAQEAARLRQ 2322
Query: 580 QDKNSRGQARVI---KIREELINVLKNKETEQSRELAALQQDL-EHRMRIVDEVNKQIAA 635
+ Q R + ++E++ V + + EL Q++L + + R + E +Q+A
Sbjct: 2323 LAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2382
Query: 636 K-ADEIQELFATLENKQQQ 653
+ A+E Q TLE ++Q+
Sbjct: 2383 QLAEETQGFQRTLEAERQR 2401
Score = 56.0 bits (129), Expect = 4e-07
Identities = 88/511 (17%), Positives = 208/511 (40%), Gaps = 31/511 (6%)
Query: 216 AVGEALVREVAKLRQDVETRNVMIDEIRELRSESENT---KALEEMRHELDEERTAKLAI 272
AV E L +E A L +++E ++E + + N L+ + ++ E A A
Sbjct: 1270 AVREQLRQEQALL-EEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1328
Query: 273 KEKLTT-TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK 331
K K+ + +ES +++ + + I ++ T++ +E++ R E Q +
Sbjct: 1329 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1388
Query: 332 LRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAI-------QQLEED 381
L E +L+ Q + + E E +Q++++ V+ + A + ++E+
Sbjct: 1389 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1448
Query: 382 LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTERE 441
L+Q +++ + + + R+ E ER+ +++ + LQ + E ++ +L R
Sbjct: 1449 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVV-RLQLEATERQRGGAEGELQALRA 1507
Query: 442 IDLWAEL---QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE----EIIGK 494
AE QA +E R+ +R++++E ++ + K AE ++ + + +
Sbjct: 1508 RAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEE 1567
Query: 495 MQIQTRELIKNIKLNE-----QKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQE- 548
+++Q E + ++ E Q + E R +A ++ + LQ+E
Sbjct: 1568 LRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEH 1627
Query: 549 --IMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKET 606
+ L+ + + E + ++ELE+ + R+ EE+ +
Sbjct: 1628 VAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQA 1687
Query: 607 EQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVLALXX 666
E ++ +++ R + ++ +Q E+++ E QQ E+ ++ L
Sbjct: 1688 EAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA 1747
Query: 667 XXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
++A L+ E AA +++
Sbjct: 1748 ETEQGEQQRQLLEEELARLQREAAAATQKRQ 1778
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/257 (20%), Positives = 119/257 (46%), Gaps = 16/257 (6%)
Query: 188 ELKTQAEDAVNTVTDLSK---RACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRE 244
E+ +AE V ++S+ RA + + E + ++ + + + ++ +
Sbjct: 2404 EMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEI 2463
Query: 245 LRSESEN-TKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT--RNRVAKMDKQLREAE 301
R +S++ + L E EL+ E+ KL + KL +S+ QT + ++ + + L+++
Sbjct: 2464 QRQQSDHDAERLREAIAELEREKE-KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSF 2522
Query: 302 ASIT-SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLEC 360
S SL + +E + + E + K ++ + + Q+ Q+R L A + E
Sbjct: 2523 LSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA 2582
Query: 361 KQ---QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIE-LKERTETELQDSRNA 416
++ + E+ + + +QQLE+ +Q + L E+ + + +++ L+E+ L S
Sbjct: 2583 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHS--- 2639
Query: 417 IEELQAKIIELEKSKPN 433
EE+ A + K+ PN
Sbjct: 2640 -EEVTASQVAATKTLPN 2655
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 68.5 bits (160), Expect = 7e-11
Identities = 113/488 (23%), Positives = 228/488 (46%), Gaps = 65/488 (13%)
Query: 190 KTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDE-IRELRSE 248
K Q ++ + T+L C E L A A +E+ ++ D+E R +E + L++E
Sbjct: 746 KLQLQEQLQAETEL----CAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAE 801
Query: 249 SENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSL 307
+ + ++E+ +L+EE +A+ ++ + TTE++L+ K++++L + +
Sbjct: 802 KKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK-------KLEEELDDLLVDL--- 851
Query: 308 TGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKL 367
D RQ LE + +K + L + +++ +RD +AE E ++ + L
Sbjct: 852 --------DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGERDRAEAEARE--KETKAL 901
Query: 368 TVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
S + LEE A++++ E+ + L ++ TE++D ++ +++ + EL
Sbjct: 902 -----SLARALEE-------AMEQKAELER----LNKQFRTEMEDLMSSKDDVGKSVHEL 945
Query: 428 EKSK-----PNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLA 482
EKSK ++ T+ E +L ELQAT++ E + K + E + +Q +
Sbjct: 946 EKSKRALEQQVEEMKTQLE-ELEGELQATEDAKLRLEVNLQAMKAQFERD----LQGRDE 1000
Query: 483 AELLNKEEIIGKMQIQTRELIKNIKLNEQKVI---QYEQYVRDLQAHNRTIANCQESPNG 539
K++++ +++ EL K V + E ++DL+AH + AN
Sbjct: 1001 QSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS-ANKNRDEAI 1059
Query: 540 ISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELIN 599
+ LQ ++ D M+ LD + E EILA Q E + K +A +I+++EEL
Sbjct: 1060 KQLRKLQAQMKDC-MRELDDTRASRE--EILA---QAKENEKKLKSMEAEMIQLQEELAA 1113
Query: 600 VLKNK-ETEQSR-ELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIH-R 656
+ K + +Q R ELA + + + E +++ A+ +++E + + I+ R
Sbjct: 1114 AERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDR 1173
Query: 657 LEKIVLAL 664
L+K L +
Sbjct: 1174 LKKANLQI 1181
Score = 56.0 bits (129), Expect = 4e-07
Identities = 102/503 (20%), Positives = 213/503 (42%), Gaps = 49/503 (9%)
Query: 154 KTNLTVNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRT 213
+ LT + + + +I L ++ E C L+ K + + + + + + R+
Sbjct: 767 RARLTAKKQELE-EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQK 825
Query: 214 LIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIK 273
L ++ KL ++++ V +D R+ E K ++ L EE+T
Sbjct: 826 LQLEKVTTEAKLKKLEEELDDLLVDLDHQRQSACNLE--KKQKKFDQLLAEEKTISAKYA 883
Query: 274 EKLTTTESQLRQTRNRVAKMDKQLREA---EASITSLTGTVKM-LEDQSRQKEVQLEARA 329
+ E++ R+ + + + L EA +A + L + +ED K+ +
Sbjct: 884 GERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKD-DVGKSV 942
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL 389
+L +S + E ++ Q + L+ E+ + +L V ++ Q E DL +
Sbjct: 943 HELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDL----QGR 998
Query: 390 QEQCEITKREIELKER-TETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
EQ E K+++ + R E EL+D R Q + + K DL +L
Sbjct: 999 DEQSEEKKKQLVRQVREMEAELEDERK-----QRSMAVAARKKLEMDL---------KDL 1044
Query: 449 QATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKL 508
+A ++ DE R+ +++ K ++L ++EEI+ Q +E K +K
Sbjct: 1045 EAHIDSANKNRDEAIKQLRKLQAQMK-DCMRELDDTRASREEILA----QAKENEKKLKS 1099
Query: 509 NEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSE 568
E ++IQ ++ +L A R Q+ + +L EI + K + L
Sbjct: 1100 MEAEMIQLQE---ELAAAERAKRQAQQERD-----ELADEIANSSGKGALALEEKRRLEA 1151
Query: 569 ILAKKDQELEQQDKNSRGQARVIKIREELINV-LKNKETEQSRELAALQQDLEHRMRIVD 627
+A+ ++ELE++ +G +I R + N+ + T+ + E + Q++ E+ + ++
Sbjct: 1152 RIAQLEEELEEE----QGNTELINDRLKKANLQIDQINTDLNLERSHAQKN-ENARQQLE 1206
Query: 628 EVNKQIAAKADEIQELFATLENK 650
NK++ K +QE+ T+++K
Sbjct: 1207 RQNKELKVK---LQEMEGTVKSK 1226
Score = 48.0 bits (109), Expect = 1e-04
Identities = 79/410 (19%), Positives = 183/410 (44%), Gaps = 31/410 (7%)
Query: 315 EDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE---KLTVQH 371
E+ + +E QL A R L E ++ +Q ++ LQAE C + E +LT +
Sbjct: 716 EELVKVREKQLAAENR-LTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAK- 773
Query: 372 KSAIQQLEEDLKQTKRALQEQC---EITKREIELK-ERTETELQDSRNAIEELQ------ 421
K ++++ DL+ +E+C + K++++ + E +L++ +A ++LQ
Sbjct: 774 KQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTT 833
Query: 422 -AKIIELEKSKPN--PDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
AK+ +LE+ + DL +R+ E + K + E++ + K E +
Sbjct: 834 EAKLKKLEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGERDRAEAEA 893
Query: 479 QKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN 538
++ + L+ + + Q EL +LN+Q + E + +++ ++S
Sbjct: 894 REKETKALSLARALEEAMEQKAEL---ERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 950
Query: 539 GISYQ--DLQQEIMDLKMKLL---DVVHRNE-ELSEILAKKDQELEQQDKNSRGQAR-VI 591
+ Q +++ ++ +L+ +L D R E L + A+ +++L+ +D+ S + + ++
Sbjct: 951 ALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLV 1010
Query: 592 KIREELINVLKNKETEQSRELAA---LQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
+ E+ L+++ ++S +AA L+ DL+ +D NK ++++L A ++
Sbjct: 1011 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1070
Query: 649 NKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKER 698
+ +++ + ++ L+ ELAA K +
Sbjct: 1071 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQ 1120
Score = 46.0 bits (104), Expect = 5e-04
Identities = 58/257 (22%), Positives = 105/257 (40%), Gaps = 21/257 (8%)
Query: 167 DILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVA 226
D+ H+ N E LR+L+ Q +D + + D RA E A +E
Sbjct: 1043 DLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT--RASREEIL------AQAKENE 1094
Query: 227 KLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT 286
K + +E + + E EL + + ++ R EL +E A + K L E R+
Sbjct: 1095 KKLKSMEAEMIQLQE--ELAAAERAKRQAQQERDELADE-IANSSGKGALALEEK--RRL 1149
Query: 287 RNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL 346
R+A+++++L E + + + +K Q Q L R + E QL
Sbjct: 1150 EARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE----RSHAQKNENARQQL 1205
Query: 347 IQQRDSLQAEVLECKQQIE---KLTVQHKSA-IQQLEEDLKQTKRALQEQCEITKREIEL 402
+Q L+ ++ E + ++ K ++ A I QLEE L + Q C+ +R +
Sbjct: 1206 ERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKK 1265
Query: 403 KERTETELQDSRNAIEE 419
+ ++ D R E+
Sbjct: 1266 LKDVLLQVDDERRNAEQ 1282
Score = 45.2 bits (102), Expect = 8e-04
Identities = 72/399 (18%), Positives = 167/399 (41%), Gaps = 19/399 (4%)
Query: 261 ELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQ 320
E E+ T L++ L Q + + ++ + +S + +V LE R
Sbjct: 892 EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRA 951
Query: 321 KEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE 380
E Q+E +L E + T ++ +LQA + ++ ++ Q + +QL
Sbjct: 952 LEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 1011
Query: 381 DLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTE- 439
+++ + L+++ + + +++ E +L+D I+ E K +
Sbjct: 1012 QVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKD 1071
Query: 440 --REIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
RE+D + +A++E + E + E+E I +Q++LAA E + Q
Sbjct: 1072 CMRELD---DTRASREEILAQAKENEKKLKSMEAE-MIQLQEELAA----AERAKRQAQQ 1123
Query: 498 QTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLL 557
+ EL I + K + R L+A + E G + +L + + +
Sbjct: 1124 ERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNT--ELINDRLKKANLQI 1181
Query: 558 DVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE----TEQSRELA 613
D ++ + L A+K++ QQ + + +V K+ +E+ +K+K T ++A
Sbjct: 1182 DQINTDLNLERSHAQKNENARQQLERQNKELKV-KL-QEMEGTVKSKYKASITALEAKIA 1239
Query: 614 ALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQ 652
L++ L++ + KQ+ +++++ ++++++
Sbjct: 1240 QLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERR 1278
Score = 40.7 bits (91), Expect = 0.017
Identities = 40/174 (22%), Positives = 75/174 (43%), Gaps = 13/174 (7%)
Query: 229 RQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRN 288
++ +E R ++E EL E NT+ + + L + I L S ++ N
Sbjct: 1146 KRRLEARIAQLEE--ELEEEQGNTELIND---RLKKANLQIDQINTDLNLERSHAQKNEN 1200
Query: 289 RVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL----KTGEVTTS 344
++++Q +E + + + GTVK + + LEA+ +L E L K +
Sbjct: 1201 ARQQLERQNKELKVKLQEMEGTVK---SKYKASITALEAKIAQLEEQLDNETKERQAACK 1257
Query: 345 QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
Q+ + L+ +L+ + + Q+K + LKQ KR L+E E +R
Sbjct: 1258 QVRRTEKKLKDVLLQVDDE-RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQR 1310
>AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ36144 fis, clone TESTI2025022, weakly similar to
TRICHOHYALIN. ).
Length = 650
Score = 68.5 bits (160), Expect = 7e-11
Identities = 77/353 (21%), Positives = 168/353 (47%), Gaps = 21/353 (5%)
Query: 181 ELCGALRELKTQAEDAVNTVTDLSKRA---CHERRTLIAVGEALVREVAKLRQDV---ET 234
EL AL + T+ + A + +L+K E E L ++ A+L++ + E+
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAES 239
Query: 235 RNVMID-EIRELRSESENTKAL--EEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVA 291
I ++EL+ + E K L + + L EE + +E+L E ++R+ ++
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ---EEELREQEKKIRKQEEKMW 296
Query: 292 KMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRD 351
+ +++LRE E + + E + R++E +L + ++LRE K E Q+ +Q +
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKKLRE-QEEQMQEQEE 355
Query: 352 SLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQ 411
+ + + ++Q EK+ Q + +Q E+ +++ ++ +++Q E + E E ++
Sbjct: 356 KMWEQEEKMREQEEKMWRQEERLWEQ-EKQMREQEQKMRDQEERMWEQDERLREKEERMR 414
Query: 412 DSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKES 471
+ E+++ K+ E +K + ++E + E + + ++ E+E T +E
Sbjct: 415 EQEKMWEQVE-KMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM----REQ 469
Query: 472 ENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQ--KVIQYEQYVRD 522
E K+ Q++ E KE ++ Q +L + K+ EQ K+ + E+ +RD
Sbjct: 470 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Score = 67.3 bits (157), Expect = 2e-10
Identities = 65/284 (22%), Positives = 130/284 (45%), Gaps = 17/284 (5%)
Query: 210 ERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAK 269
E R G+ +E RQ+ R E+RE E K L E ++ E+
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLRE-QEKELREQEKELREQKKLREQEEQMQEQEEKM 357
Query: 270 LAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARA 329
+EK+ E ++ + R+ + +KQ+RE E KM + + R E + R
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ---------KMRDQEERMWE--QDERL 406
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL 389
R+ E ++ E Q+ + R+ + + E K + ++ +Q + I++ E+ +++ + +
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466
Query: 390 QEQCE-ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAEL 448
+EQ E + K+E + E+ E E Q R + E + K+ E EK + + E+E + +
Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQR--LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 524
Query: 449 QATKETLRVTEDEVTTCKRE--KESENKIGIQQKLAAELLNKEE 490
+ + ++ ++E + E +E E +I Q++ E L + E
Sbjct: 525 EMWGQEKKMWQEEKMWGQEEMMREKEERIRDQKEKMQERLPEHE 568
Score = 47.2 bits (107), Expect = 2e-04
Identities = 59/272 (21%), Positives = 132/272 (48%), Gaps = 14/272 (5%)
Query: 381 DLKQTKRALQEQCEITKREIE--LKERTETELQDSRNAI--EELQAKIIELEKSKPNPDL 436
+L++ A+ + + R IE KER L+ RN I EEL+ K EL++ P +
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAE- 238
Query: 437 PTEREIDLWA-ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKM 495
+ EI L EL+ E + +V T ++E + ++ ++ +EE + +
Sbjct: 239 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 298
Query: 496 QIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMK 555
+ + RE ++ E+K+ + E+ +R+ + R +E ++ ++++ + + K
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQE--KELREQKKLREQEEQMQEQEEK 356
Query: 556 LLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI----NVLKNKETEQSRE 611
+ + + E E + ++++ L +Q+K R Q + ++ +EE + L+ KE E+ RE
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMRE 415
Query: 612 LAALQQDLEHRMRIVDEVNKQIAAKADEIQEL 643
+ + +E +MR ++ +Q D+ +++
Sbjct: 416 QEKMWEQVE-KMREEKKMQEQEKKTRDQEEKM 446
Score = 39.9 bits (89), Expect = 0.030
Identities = 64/295 (21%), Positives = 132/295 (44%), Gaps = 20/295 (6%)
Query: 376 QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPD 435
QQ LK+ K+A + E +REIE ++ T L + +E + + + +
Sbjct: 73 QQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGN 132
Query: 436 LPTEREIDLWAELQATK-------ETLRVTEDEVTTCKREKESENKIG-IQQKLAAELLN 487
L T +L A QA + T + + R S + G +Q+ L+A
Sbjct: 133 LGTPSSFNL-ALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRALSAVSTR 191
Query: 488 KEEIIGKMQIQTREL-IKNIKLNEQKVIQYEQYVRDLQAHNRT-IANCQESPNGISYQDL 545
++ ++ T+E +++L + E ++ + + +A ++S ++ ++L
Sbjct: 192 HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKEL 251
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
++++ K LL V N L E + ++++EL +Q+K R Q + +EE + + K
Sbjct: 252 KRKLERAKF-LLPQVQTNT-LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 309
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
EQ ++ +Q E R+R E K++ + E++E E ++Q + EK+
Sbjct: 310 REQEEKM--WRQ--EKRLR---EQEKELREQEKELREQKKLREQEEQMQEQEEKM 357
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 68.5 bits (160), Expect = 7e-11
Identities = 105/518 (20%), Positives = 215/518 (41%), Gaps = 51/518 (9%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIREL 245
L E Q + +TV+ + K + + +E K R + + D++ +L
Sbjct: 145 LDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDL 204
Query: 246 RSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASIT 305
+ S+N++ E +L ++ + + T +LR++ ++K QL +
Sbjct: 205 KKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQ 264
Query: 306 SLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIE 365
++ + Q+ + QL+A R L + SLQ EV K +E
Sbjct: 265 ERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLE 324
Query: 366 KLTVQHKSA----------IQQLEEDLKQTKRALQEQCE-------ITKREIELKERT-- 406
K+ + K A LE DL ++LQ++ E +TK + K ++
Sbjct: 325 KVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIE 384
Query: 407 ----------ETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLR 456
E +L++ R A E+ + +++++EK D+ ++ L KE +
Sbjct: 385 EAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERM- 443
Query: 457 VTEDEV--TTCKREKESENKIGIQQKLAAELLNKEEIIG---KMQIQTRELIKNIKLNEQ 511
EDEV T + E+ES ++ +Q +L + + + G +M+ + L++ +L E
Sbjct: 444 --EDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEF 501
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGIS------YQDLQQEIMDLKMKLLDVVHRNEE 565
++ Q + R + R + + E+ S ++L++EI + + L + +
Sbjct: 502 ELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQN 561
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRI 625
E LA + +L + S AR + + E+ + + + SR + D +H +
Sbjct: 562 EKETLATQ-LDLAETKAESEQLARGL-LEEQYFELTQESKKAASRNRQEI-TDKDHTVSR 618
Query: 626 VDEVN----KQIAAKADEIQELFATLENKQQQIHRLEK 659
++E N K I E +EL ++ K ++ ++LEK
Sbjct: 619 LEEANSMLTKDIEILRRENEELTEKMK-KAEEEYKLEK 655
Score = 64.1 bits (149), Expect = 2e-09
Identities = 81/317 (25%), Positives = 147/317 (46%), Gaps = 31/317 (9%)
Query: 227 KLRQDVETRNVMIDEIRELRSESENTK--ALEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+L Q+V V + + E K A+ EM +L EER A+ EK E+++
Sbjct: 361 RLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAR----EK---AENRVV 413
Query: 285 QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLKTGEV 341
Q + + +D L++++ + LTG + +ED+ + +QLE + K L+ LKT
Sbjct: 414 QIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAF 473
Query: 342 TTSQLIQQRDSLQAEV---LECKQQIE----KLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
L ++ E+ LE K+ +E +LT Q++ Q+ E L+ A Q
Sbjct: 474 EADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRE-LQDQLEAEQYFST 532
Query: 395 ITKREI-ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDL-PTEREIDLWAELQATK 452
+ K ++ ELKE E + +++ I+ELQ E E DL T+ E + A +
Sbjct: 533 LYKTQVKELKEEIEEKNRENLKKIQELQN---EKETLATQLDLAETKAESEQLARGLLEE 589
Query: 453 ETLRVTEDEVTTCKREK-ESENKIGIQQKL--AAELLNKE-EIIGKMQIQTRELIKNIKL 508
+ +T++ R + E +K +L A +L K+ EI+ + + E +K K
Sbjct: 590 QYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMK--KA 647
Query: 509 NEQKVIQYEQYVRDLQA 525
E+ ++ E+ + +L+A
Sbjct: 648 EEEYKLEKEEEISNLKA 664
Score = 44.8 bits (101), Expect = 0.001
Identities = 73/395 (18%), Positives = 166/395 (42%), Gaps = 35/395 (8%)
Query: 268 AKLAIKEKLTTTESQLR-QTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLE 326
A +++E L T +L Q N + D+ ++ S L +K L+++ Q+ LE
Sbjct: 98 ADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR-NLE 156
Query: 327 ARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK 386
+ ++ + L+Q R + E + + + S ++ EDLK+
Sbjct: 157 STVSQIEKE--------KMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKV- 207
Query: 387 RALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWA 446
+ ++ ++ + + +L+++ + + + L KS + L
Sbjct: 208 ---SQNSQLANEKL---SQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNR 261
Query: 447 ELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQ---TRELI 503
ELQ E R+ E+ + + +K+ I + + + E+IG +Q + +E +
Sbjct: 262 ELQ---ERNRILEN--SKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEV 316
Query: 504 KNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRN 563
K++K N +KV + +D+ H+ ++ N + DL ++ L+ +L V+ +
Sbjct: 317 KHLKHNLEKVEGERKEAQDMLNHS------EKEKNNLEI-DLNYKLKSLQQRLEQEVNEH 369
Query: 564 EELSEILAKKDQELEQQDKNSRGQ-ARVIKIREELINVLKNKETEQSRELAALQQDLEHR 622
+ L K Q +E+ + + + +K E +N+ + ++ + L DL+
Sbjct: 370 KVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQS 429
Query: 623 MRIVDEVNKQIAAKADEIQELFATLENKQQQIHRL 657
+ ++ + DE++ L TL+ +Q+ RL
Sbjct: 430 QQKLEHLTGNKERMEDEVKNL--TLQLEQESNKRL 462
Score = 35.9 bits (79), Expect = 0.49
Identities = 55/288 (19%), Positives = 128/288 (44%), Gaps = 24/288 (8%)
Query: 373 SAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKP 432
+A + L+E L++T L+EQ E++LK+ E + + S ++++ ++ E +
Sbjct: 97 NADKSLQESLQKTIYKLEEQLH---NEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRR 153
Query: 433 NPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEII 492
N + ++++ K L+ +E K E+E+E + ++ +++ K+++
Sbjct: 154 NLESTV-------SQIEKEKMLLQHRINEYQR-KAEQENEKRRNVENEVSTL---KDQLE 202
Query: 493 GKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDL 552
++ + N KL++ + Q E+ L+ + T ++S + ++ + I L
Sbjct: 203 DLKKVSQNSQLANEKLSQLQK-QLEEANDLLRTESDTAVRLRKS-----HTEMSKSISQL 256
Query: 553 KMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSREL 612
+ ++ RN L ++ D++ Q + R E+I L+ + T E+
Sbjct: 257 ESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEV 316
Query: 613 AALQQDLE----HRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHR 656
L+ +LE R D +N K + +L L++ QQ++ +
Sbjct: 317 KHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQ 364
>X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein.
Length = 1263
Score = 68.1 bits (159), Expect = 1e-10
Identities = 72/338 (21%), Positives = 158/338 (46%), Gaps = 24/338 (7%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-----LEEMRHELDEERTAKLAIKEKLTTTE 280
AKL++ +E + +++++E +S+ + +A L+E R E E AK E++ T
Sbjct: 228 AKLKE-LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 286
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+ +A +DK++ E A SL V+ L+++ + LE ++ E G
Sbjct: 287 DAIE-----MATLDKEMAEERAE--SLQQEVEALKERVDELTTDLEILKAEIEEKGSDGA 339
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI 400
++ QL +Q + A + + ++ L+ K +L++ +++ + L E+ +++
Sbjct: 340 ASSYQL-KQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL----EVVRQQ- 393
Query: 401 ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
+ER + EL + + I+EL+ ++ ++ ++ T+R ++L +++ +ET V +
Sbjct: 394 --RERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRET--VGDL 449
Query: 461 EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYV 520
E ++ EN + +L +L + + Q + + + +Q + +Y Q
Sbjct: 450 EAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLT 509
Query: 521 RDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD 558
LQ NR + N QE+ + Q E D K+K +
Sbjct: 510 AHLQDVNRELTNQQEA-SVERQQQPPPETFDFKIKFAE 546
Score = 62.1 bits (144), Expect = 6e-09
Identities = 84/355 (23%), Positives = 159/355 (44%), Gaps = 32/355 (9%)
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
G V L S+++E L A+ R L E L+T +L + D + + LE K +I+
Sbjct: 190 GAVPPLPSPSKEEE-GLRAQVRDLEEKLET-----LRLKRAEDKAKLKELE-KHKIQLEQ 242
Query: 369 VQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
VQ KS +Q+ + DL+ R L+E + K +E KER E+ D+ +AIE + L
Sbjct: 243 VQEWKSKMQEQQADLQ---RRLKEARKEAKEALEAKERYMEEMADTADAIE-----MATL 294
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
+K ++ ER L E++A KE + ++ K E E + G + L
Sbjct: 295 DK-----EMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLE 349
Query: 488 KEEI-IGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQDL 545
++ + ++ R+L + K K+ + E+ ++L+ + QE
Sbjct: 350 EQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQE-----ELSQA 404
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
+ I +LK + +D EE+ E+L ++ LE++ + R ++ E+ + L+
Sbjct: 405 ESTIDELK-EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENA 463
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
E E L++ L+ V E K++ A + + + T++ +Q L+ +
Sbjct: 464 RETELE---LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 515
Score = 34.7 bits (76), Expect = 1.1
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 18/201 (8%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHER--RTLIAVGEALVREVAKLRQDVETRNVMI 239
L AL EL +A + + S C + LI+ L + + D E
Sbjct: 847 LVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTMNKLATAMQEGEYDAERPPSKP 906
Query: 240 D--EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL 297
E+R +E T A E + +L++ T +K+ L +L + R++ ++K+L
Sbjct: 907 PPVELRAAALRAEITDA-EGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKL 965
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
A K +++ + + +LE LR+ K E T L D L+AE
Sbjct: 966 DSA----------AKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEK 1015
Query: 358 LECKQQIEKLTVQHKSAIQQL 378
E KQ +L Q K I+ L
Sbjct: 1016 AELKQ---RLNSQSKRTIEGL 1033
>BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein
protein.
Length = 1694
Score = 68.1 bits (159), Expect = 1e-10
Identities = 70/347 (20%), Positives = 156/347 (44%), Gaps = 18/347 (5%)
Query: 325 LEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQ 384
L+ +LR+SL+ + T L + L + + K Q S I+QL+E
Sbjct: 1060 LQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDV 1119
Query: 385 TKRALQEQCEITKRE----IELKERTETELQDS---RNAIEELQAKIIELEKSKPNPDLP 437
++ L+E+ + K + + E ++ ++ R A+ L+ +I+ LE
Sbjct: 1120 LQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGE 1179
Query: 438 TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQI 497
E+ ++ + + + L+ T + + REKE E ++ LA E L KE+ GK
Sbjct: 1180 NEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGKTG- 1238
Query: 498 QTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLL 557
+ +L+ +K ++K + ++Q + +A Q+ + Q++ Q + D + +
Sbjct: 1239 ELNQLLNAVKSMQEKTVVFQQ-----ERDQVMLALKQKQMENTALQNVVQRLRDKEFRSN 1293
Query: 558 DVVH--RNEELSEILAKKDQELEQQDKNSRGQARVIKIREELI---NVLKNKETEQSREL 612
+ RN L + + L +D+ ++ + +V + E+L+ N ++N + S ++
Sbjct: 1294 QELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQV 1353
Query: 613 AALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+LQ+ L + DE Q++ +++++ +L N Q + ++
Sbjct: 1354 ESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQ 1400
Score = 56.4 bits (130), Expect = 3e-07
Identities = 83/458 (18%), Positives = 181/458 (39%), Gaps = 40/458 (8%)
Query: 251 NTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI-TSLTG 309
N+ EE+ E D + ++E + ++ ++ A++ ++L + +A +
Sbjct: 915 NSNQFEELLQERDTLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDN 974
Query: 310 TVKMLEDQSR--QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEK- 366
K+ D + Q Q E + + + L + + QL +D L ++ Q+
Sbjct: 975 NSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSA 1034
Query: 367 --LTVQHKSAIQQLEED-LKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAK 423
LT Q ++ + + L ++ LQ++ E ++ ++ K+ T LQ++ + + + A
Sbjct: 1035 SLLTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAA 1094
Query: 424 IIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAA 483
ELE+ + T+ EI E Q + L +D + K ++ + K
Sbjct: 1095 TSELERKEHE---QTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNK--- 1148
Query: 484 ELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ 543
+N+ E++ R+ + N+K ++++ E + L+ N I YQ
Sbjct: 1149 --VNENELL-------RQAVTNLK---ERILILEMDIGKLKGENEKIVETYRGKE-TEYQ 1195
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKN 603
LQ+ M M L + + E +Q L+++++ G+ +L+N +K+
Sbjct: 1196 ALQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGKTGEL------NQLLNAVKS 1249
Query: 604 KETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIVL- 662
+ + QQ+ + M + + + A + +Q L Q++ RL +L
Sbjct: 1250 MQ----EKTVVFQQERDQVMLALKQKQMENTALQNVVQRLRDKEFRSNQELERLRNHLLE 1305
Query: 663 ---ALXXXXXXXXXXXXXXXXKIAALEHELAAGLNRKE 697
+ K+ LE +L + N E
Sbjct: 1306 SEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAME 1343
Score = 54.0 bits (124), Expect = 2e-06
Identities = 78/451 (17%), Positives = 192/451 (42%), Gaps = 32/451 (7%)
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTT 278
E L + LR++ R + ++ R L S E L+E L EE++ + + T
Sbjct: 544 EELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTL 603
Query: 279 TESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKT 338
+ + + V++++ E I K++EDQ++ K +QL ++ ++ +
Sbjct: 604 --DSVTELASEVSQLNTIKEHLEEEIKHHQ---KIIEDQNQSK-MQLLQSLQEQKKEMDE 657
Query: 339 GEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKR 398
Q+ L E E + ++K Q K+ + + +D++ + ++ ++
Sbjct: 658 FRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSL 717
Query: 399 EIEL-KERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRV 457
IE E+ + ++ ++ ++ + +E+ K ++ ++ID ++ + K T +
Sbjct: 718 NIENGSEKHDLSKAETERLVKGIKERELEI-KLLNEKNISLTKQIDQLSKDEVGKLTQII 776
Query: 458 TEDEV------TTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQ 511
+ ++ +++ + +QQ+L A + +E++ + +TRE N
Sbjct: 777 QQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRE-------NSH 829
Query: 512 KVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILA 571
+Y + + + A + Q+ +S + + D+ + + + LS I+
Sbjct: 830 LKTEYHKMMDIVAAKEAALIKLQDENKKLSTR-FESSGQDMFRETI------QNLSRIIR 882
Query: 572 KKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNK 631
+KD E++ + + V++ N + Q EL + L+ +++ ++E +
Sbjct: 883 EKDIEIDALSQKCQTLLAVLQ-TSSTGNEAGGVNSNQFEELLQERDTLKQQVKKMEEWKQ 941
Query: 632 QIAAKADEIQELFATLENKQQQIHRLEKIVL 662
Q+ +Q A L Q+++H+L+ VL
Sbjct: 942 QVMTTVQNMQHESAQL---QEELHQLQAQVL 969
Score = 49.6 bits (113), Expect = 4e-05
Identities = 100/455 (21%), Positives = 208/455 (45%), Gaps = 58/455 (12%)
Query: 213 TLIAVGEALVREVAKLRQDVETRNVMIDEIR-ELRSESEN-TKALEEMRHELDEERTAKL 270
TL+ EA VR + + ++E N + ++ +++ E+E A E++RH+L+E L
Sbjct: 357 TLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEE----CL 412
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSR-QKEVQLEARA 329
A +L+ ++ + +T KM+K EAE ++LE+ ++ +K ++ + A
Sbjct: 413 AGNNQLSLEKNTIVET----LKMEKGEIEAELCWAKK----RLLEEANKYEKTIEELSNA 464
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTK--- 386
R L S ++ LI+ E+ E K+ IE Q++ D K+TK
Sbjct: 465 RNLNTSAL--QLEHEHLIKLNQKKDMEIAELKKNIE-----------QMDTDHKETKDVL 511
Query: 387 -RALQEQCEIT----KREI---ELKERT---ETELQDSRNAIEELQAKIIELEKSKPNPD 435
+L+EQ ++T K+EI +LKER+ + EL A+ + + +E+ +
Sbjct: 512 SSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLG 571
Query: 436 LPTEREIDLWAELQATKE----TLRVTEDEVTTCKREKESE-NKIG-IQQKLAAELLNKE 489
E L EL+ +E T V + + E SE +++ I++ L E+ + +
Sbjct: 572 SMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQ 631
Query: 490 EIIGKMQIQTRELIKNIKLNEQKV----IQYEQ----YVRDLQAHNRTIANCQESPNGIS 541
+II +L+++++ ++++ Q+EQ + + + I + Q++ I
Sbjct: 632 KIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIK 691
Query: 542 YQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVL 601
Q L +E D++ D+ + S + ++ + + + IK RE I +L
Sbjct: 692 TQ-LHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLL 750
Query: 602 KNKETEQSRELAALQQDLEHRM-RIVDEVNKQIAA 635
K ++++ L +D ++ +I+ + + +I A
Sbjct: 751 NEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQA 785
Score = 48.4 bits (110), Expect = 9e-05
Identities = 108/566 (19%), Positives = 231/566 (40%), Gaps = 61/566 (10%)
Query: 137 LELLDETMPIENII-KYPKTNLTVNQDQTDGDILEH-LSRYNDQGFELCGALRELKTQAE 194
+E ++ T +E + K N ++ + D DIL + N + ++ LK +
Sbjct: 43 IEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECS 102
Query: 195 DAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQ---DVETRNVMIDEIRE------- 244
+ S + R L A V EV +L+Q D E + + + +
Sbjct: 103 KLQPSAVKQSDTMTEKERILAQ--SASVEEVFRLQQALSDAENEIMRLSSLNQEELQMSL 160
Query: 245 --LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEA 302
L +E E K+ LD E ++ L E +L Q+ + + ++ E +
Sbjct: 161 LKLNNEYEVIKSTATRDISLDSELHD---LRLNLEAKEQELNQSISEKETLIAEIEELDR 217
Query: 303 SITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQL-------IQQRDSLQA 355
T + +++DQ +++ + ++ KL++ L + QL ++ D +
Sbjct: 218 QNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKE 277
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRN 415
++++ + + L + + ++E + Q ++ + I K +ELKE ++
Sbjct: 278 KLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSR 337
Query: 416 AIEELQAKIIELEKSKPNPDLPTEREIDL------WAELQATKETLRVTEDEVTTCKREK 469
EL + + S L ERE ++ +EL+ E L+ +V K E
Sbjct: 338 IRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDV---KMEN 394
Query: 470 E------SENKIGIQQKLAAE---LLNKEEIIGKMQIQTRELIKNIKLNEQKVIQ----Y 516
E + + +++ LA L K I+ ++++ E+ + ++++++ Y
Sbjct: 395 EKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKY 454
Query: 517 EQYVRDL-QAHNRTIANCQ-ESPNGISY-QDLQQEIMDLKMKLLDVVHRNEELSEILAKK 573
E+ + +L A N + Q E + I Q EI +LK + + ++E ++L+
Sbjct: 455 EKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLS-- 512
Query: 574 DQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDL---EHRMRIVDEVN 630
LE+Q + ++I +E I LK + ++ EL Q L E + ++E +
Sbjct: 513 -SSLEEQ----KQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKD 567
Query: 631 KQIAAKADEIQELFATLENKQQQIHR 656
+ + + +E L LE +++ R
Sbjct: 568 RSLGSMKEENNHLQEELERLREEQSR 593
Score = 39.5 bits (88), Expect = 0.039
Identities = 61/294 (20%), Positives = 128/294 (43%), Gaps = 28/294 (9%)
Query: 208 CHERRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHE----LD 263
CH + E L++E K + N +++ ++ ++ E T ++ R + L
Sbjct: 1215 CHSMKEKALAFEQLLKE--KEQGKTGELNQLLNAVKSMQ---EKTVVFQQERDQVMLALK 1269
Query: 264 EERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEV 323
+++ A++ + + ++ + ++ L E+E S T + E + R+K
Sbjct: 1270 QKQMENTALQNVVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVT 1329
Query: 324 QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEE--- 380
LE KL S E + Q Q +SLQ ++ +Q ++ +Q + +Q+++
Sbjct: 1330 VLE---EKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYAL 1386
Query: 381 DLKQTKRALQ--EQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT 438
L + L+ +Q E EL+++ + + +NA E L+ K+I L++ +
Sbjct: 1387 SLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNA-ENLEGKVISLQECLDEANAAL 1445
Query: 439 EREIDLWAELQATKETLRVTEDEVTTCKREKESENKI--GIQQKLAAELLNKEE 490
+ L E L V E+++ KR+ E ++ +Q+KL + L N E
Sbjct: 1446 DSASRL-------TEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMS-LANSSE 1491
Score = 37.5 bits (83), Expect = 0.16
Identities = 65/272 (23%), Positives = 124/272 (45%), Gaps = 32/272 (11%)
Query: 409 ELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE 468
EL D IEEL+ +++ S E ++ E+Q T + L++ ++V + K+
Sbjct: 1 ELSDYEERIEELE-NLLQQGGSGV-----IETDLSKIYEMQKTIQVLQI--EKVESTKKM 52
Query: 469 KESENKI-GIQQKLAA-----ELLNKE-EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVR 521
++ E+KI I +KL++ ++L +E E + + Q E +N+KL K+
Sbjct: 53 EQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQS 112
Query: 522 DLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRN-EELSEILAKKDQELE-- 578
D I S + LQQ + D + +++ + N EEL L K + E E
Sbjct: 113 DTMTEKERILAQSASVEEVFR--LQQALSDAENEIMRLSSLNQEELQMSLLKLNNEYEVI 170
Query: 579 ----QQDKNSRGQARVIKIR-----EELINVLKNKET--EQSRELAALQQDL-EHRMRIV 626
+D + + +++ +EL + KET + EL Q+ +H + I
Sbjct: 171 KSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIK 230
Query: 627 DEVNKQIAAKADEIQELFATLENKQQQIHRLE 658
D+++KQ I +L L ++++++H+LE
Sbjct: 231 DQLSKQQNEGDSIISKLKQDLNDEKKRVHQLE 262
>BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein
protein.
Length = 971
Score = 68.1 bits (159), Expect = 1e-10
Identities = 101/489 (20%), Positives = 215/489 (43%), Gaps = 52/489 (10%)
Query: 186 LRELKTQAEDAVNTVTDLSKRACHE-----RRTLIAVGEALVREVAKLRQDVETRNVMID 240
L+ L+++ E+ V + + + E + AV +R+ KL+ D+E ++
Sbjct: 341 LKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQH---- 396
Query: 241 EIRELRSESENTKALEEMRHELDEE-RTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLRE 299
+++ LEE +++L +E K +++KL T ++ ++ V K ++ L
Sbjct: 397 --------NKDKLNLEEDKNQLQQELENLKEVLEDKLDTANQEIGHLQDMVRKSEQGLGS 448
Query: 300 AEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLE 359
AE I SL Q Q+ +Q E K +SLK T L+ L+ E +
Sbjct: 449 AEGLIASL---------QDSQERLQNELDLTK--DSLKE---TKDALLNVEGELEQERQQ 494
Query: 360 CKQQIEKLTVQHKSAIQQLEEDLK-QTKRALQEQCEITKREIELKERTETELQDSRNAIE 418
++ I + + K + ++ DL+ + L+++C + E+ L+ +D ++A+
Sbjct: 495 HEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHE-----EDKKSAMS 549
Query: 419 ELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQ 478
+L ++ + EK+ + E DL ++ K+ L + + T ++ +++ +
Sbjct: 550 QL-LQLKDREKNAARDSWQKKVE-DLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQE-R 606
Query: 479 QKLAAELLNKEEIIGKMQIQTRE--LIKNIKLNEQKVIQYEQYVRDLQA-HNRTIANCQ- 534
Q+L EL EE + +E ++ + E+K + LQ H+ + + +
Sbjct: 607 QRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKD 666
Query: 535 ---ESPNGISYQDLQQEIMDLKMKLLDV--VHRNEELSEILAKKDQELEQQDKNSRGQAR 589
ES G+ + ++QE+ L+ +L D SE+ + ++ N +
Sbjct: 667 AHRESMEGLRIE-MEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELA 725
Query: 590 VIKIR-EELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLE 648
K+ E I++ + + E + LQ++L HR + E++K++ + I L LE
Sbjct: 726 AAKMELERSIDISRRQSKEHICRITDLQEELRHREHRISELDKEVQHLHENISALTKELE 785
Query: 649 NKQQQIHRL 657
K ++I R+
Sbjct: 786 FKGKEILRI 794
Score = 55.6 bits (128), Expect = 6e-07
Identities = 106/457 (23%), Positives = 202/457 (44%), Gaps = 61/457 (13%)
Query: 253 KALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK 312
K + +++ EL + ++ +K ++ L N V + KQL +A+ +L K
Sbjct: 180 KTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHK 239
Query: 313 MLEDQ--SRQKEVQLEARARKLRES----LKTGEVTTSQLIQQRDSLQAEVLECKQQIEK 366
+E + + ++ +Q +A L+ S L+ ++T I+ +S ++ V E Q+E+
Sbjct: 240 EVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEE 299
Query: 367 LTVQHKSAIQQLEEDLKQTKRALQEQCEITKR------EIELK------ERTETELQDSR 414
+S Q L+E+ KQ L+++ KR E ELK E T+L ++
Sbjct: 300 ERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAH 359
Query: 415 N-AIEELQAK---IIEL-------EKSKPNPDLPTEREIDLW------AELQATKETLR- 456
+ +EEL K IE +K K DL + D +LQ E L+
Sbjct: 360 SKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKE 419
Query: 457 VTEDEVTTCKRE--------KESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIK- 507
V ED++ T +E ++SE +G + L A L + +E + T++ +K K
Sbjct: 420 VLEDKLDTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKD 479
Query: 508 --LNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEE 565
LN + ++ E+ Q H TIA +E + + DL++K + + +E
Sbjct: 480 ALLNVEGELEQER-----QQHEETIAAMKEEEK----LKVDKMAHDLEIKWTE--NLRQE 528
Query: 566 LSEILAKKDQELEQQDKNSRGQARVIKIREE--LINVLKNKETEQSRELAALQQDLEHRM 623
S++ + + E+ K++ Q +K RE+ + + K + +++ L+Q+LE ++
Sbjct: 529 CSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQL 588
Query: 624 RIVDEVNKQIAAK-ADEIQELFATLENKQQQIHRLEK 659
+Q+ A+ E Q L LE ++Q + K
Sbjct: 589 SQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHK 625
Score = 39.1 bits (87), Expect = 0.052
Identities = 33/150 (22%), Positives = 68/150 (45%), Gaps = 3/150 (2%)
Query: 225 VAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLR 284
+A LR ++ ++ ++ E A E+ +D R ++T + +LR
Sbjct: 698 LASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELR 757
Query: 285 QTRNRVAKMDKQLREAEASITSLTGTV--KMLEDQSRQKEVQLEARARKLRESLKTGEVT 342
+R++++DK+++ +I++LT + K E + E + R ++ E E +
Sbjct: 758 HREHRISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLEEMEEKYLMRE-S 816
Query: 343 TSQLIQQRDSLQAEVLECKQQIEKLTVQHK 372
+ IQ L+A + E Q I+KL +K
Sbjct: 817 KPEDIQMITELKAMLTERDQIIKKLIEDNK 846
>BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.
Length = 1726
Score = 68.1 bits (159), Expect = 1e-10
Identities = 106/464 (22%), Positives = 209/464 (45%), Gaps = 46/464 (9%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEE--MRHELDEERTAKLAIKEKLTTTESQL 283
+ L Q V+ RN D R+L S +N + L++ + + L +++ ++A K K+ + S
Sbjct: 865 SNLNQVVQERN---DAQRQL-SREQNARMLQDGILTNHLSKQKEIEMAQK-KMNSENSHS 919
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQ----LEARARKLRESLKTG 339
+ ++ + L+E A + T+K + +K + ++ + L++++K
Sbjct: 920 HEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQN 979
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL------QEQC 393
E T +Q I Q + + + + K + ++LE +++ L ++Q
Sbjct: 980 EETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQS 1039
Query: 394 EITKREIEL---KERTE-TELQDSRNA-IEELQA--KIIELEKSKPNPDLPTEREIDLWA 446
E +KRE+EL + R E + LQD N + L+ +I+ + K L EI+
Sbjct: 1040 ETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKL-NSLEIEFHH 1098
Query: 447 ELQATKE-TL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL 502
A +E TL RV +D T + KE E K +Q + + K+E + + Q +
Sbjct: 1099 TRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQS- 1157
Query: 503 IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+N+ L +Q + +T+ N Q+ + I Q LQ E K LL + R
Sbjct: 1158 -ENMLLRQQ----LDDAHNKADNKEKTVINIQDQFHAI-VQKLQAE--SEKQSLL-LEER 1208
Query: 563 NEEL-SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE-TEQSRELAA-----L 615
N+EL SE K+++ + +++ + + V ++++EL + LK + +E S E+ + L
Sbjct: 1209 NKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINL 1268
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ + + + + ++ Q+ D E E Q +LEK
Sbjct: 1269 EDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEK 1312
Score = 50.8 bits (116), Expect = 2e-05
Identities = 102/549 (18%), Positives = 229/549 (41%), Gaps = 64/549 (11%)
Query: 120 VAQLYRDAIASSTPENALELL-----DETMPIENIIKYPKTNLTVNQDQTDGDILEHLSR 174
+A D S T + LEL DE +++ + + +NL N + + + S+
Sbjct: 1029 LAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESK 1088
Query: 175 YNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVET 234
N E L+ + DLS+ C + + + E K+ + +
Sbjct: 1089 LNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKE----MEQKYQNEQVKVNKYIGK 1144
Query: 235 RNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLR-QTRNRVAK 292
+ + + + +L+SE+ + L++ ++ D + + I+++ +L+ ++ +
Sbjct: 1145 QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL 1204
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
++++ +E + L E++ ++EV + ++L ++LK ++ + L
Sbjct: 1205 LEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASL------ 1258
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
+ + + + Q L++ L Q + LQE + + E+ +QD
Sbjct: 1259 ---------EVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEK----MQD 1305
Query: 413 SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+ +E+ AK+ + ++++D ELQ ++EDE K+ E +
Sbjct: 1306 HKQKLEKDNAKL----------KVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELK 1355
Query: 473 NKI--GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ + Q++ + + EI G + + KLNE + ++ + DL+ ++
Sbjct: 1356 QSLECNLDQEMKKNVELEREITGFKNLLK---MTRKKLNEYENGEF-SFHGDLKT-SQFE 1410
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-SEILAKK--DQELEQQDKNSRGQ 587
+ Q + DL E+ K L + +N+ L E+L+ K ++ E+ KN +
Sbjct: 1411 MDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKK-- 1468
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI----QEL 643
K+ +E+IN+ + E R + L Q +++ I + ++IA K E+ Q
Sbjct: 1469 ----KLEQEVINLRSHIE----RNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQ 1520
Query: 644 FATLENKQQ 652
A+ EN +Q
Sbjct: 1521 AASQENLEQ 1529
Score = 48.4 bits (110), Expect = 9e-05
Identities = 83/419 (19%), Positives = 173/419 (41%), Gaps = 26/419 (6%)
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
++ EL E + K ++ + E +L R + + +++ R A+ + ++ E+Q
Sbjct: 779 LQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQ 838
Query: 318 SRQK-EV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV---LECKQQIEKLTVQH 371
R++ EV QLE + L L+T + +Q++Q+R+ Q ++ + + + H
Sbjct: 839 YRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNH 898
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK 431
S +++E K+ E K + E+ R I+ ++ + E EK K
Sbjct: 899 LSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEK-K 957
Query: 432 PNPDLP--TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE 489
DL E+ DL ++ +ETL T + +EN + + KL E +KE
Sbjct: 958 CFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAM-LNSKLENEKQSKE 1016
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GIS-----YQ 543
+ +++ L I +Q + Q + Q+ N +S +
Sbjct: 1017 RLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNE 1076
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLK 602
L Q++ + KL + + L +K LE+ K+ S+ Q ++ +E+ +
Sbjct: 1077 ILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQM----KEMEQKYQ 1132
Query: 603 NKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF----ATLENKQQQIHRL 657
N++ + ++ + Q+ +E R+ + N + + D+ T+ N Q Q H +
Sbjct: 1133 NEQVKVNKYIGK-QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAI 1190
Score = 41.5 bits (93), Expect = 0.010
Identities = 81/363 (22%), Positives = 155/363 (42%), Gaps = 61/363 (16%)
Query: 169 LEHLSRYN----DQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVRE 224
LE SRY D+ +L L +++ Q ++A + T+ + C E+ + + L ++
Sbjct: 1258 LEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVR--CAEK--MQDHKQKLEKD 1313
Query: 225 VAKLRQDVETRNVMIDEIRE-------LRSESENTKALEEMRHEL----DEERTAKLAIK 273
AKL+ V+ + I+E+++ E E K L E++ L D+E + ++
Sbjct: 1314 NAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELE 1373
Query: 274 EKLTTTESQLRQTRNRVAK------------------MDKQLREAEASITSLTGTVKMLE 315
++T ++ L+ TR ++ + MD Q+ + + I LT +
Sbjct: 1374 REITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAEL---- 1429
Query: 316 DQSRQKEVQLEARARKLRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTV--- 369
+ + K + L+ + + L+E S+KT + +L + + L+ EV+ + IE+ V
Sbjct: 1430 ETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELG 1489
Query: 370 ---QHKSAI-----QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
Q+K I Q++ E LK+ LQ Q + + +E ++ EL+
Sbjct: 1490 QVKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQM----ELR 1545
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K +E E SK + +L Q E L+V + + K K +E + KL
Sbjct: 1546 IKDLESELSKIKTSQEDFNKTELEKYKQLYLEELKVRKS--LSSKLTKTNERLAEVNTKL 1603
Query: 482 AAE 484
E
Sbjct: 1604 LVE 1606
>BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 68.1 bits (159), Expect = 1e-10
Identities = 102/474 (21%), Positives = 223/474 (47%), Gaps = 44/474 (9%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
RR L ++ E+ LR +V+ E+ + + ++ ++++ L EE+
Sbjct: 906 RRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQ 965
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARA 329
++E+L + QLR ++++ R+ + +++ D+++ EV QL
Sbjct: 966 LLQEELEALQLQLR-------ALEQETRDGGQEYV-VKEVLRIEPDRAQADEVLQLREEL 1017
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL 389
LR K L+QQR + AE E + EK+T + + +L+ D Q +
Sbjct: 1018 EALRRQ-KGAREAEVLLLQQRVAALAE--EKSRAQEKVT---EKEVVKLQND-PQLEAEY 1070
Query: 390 QEQCEITKREIELKERTETE---LQDSRNAIEELQA----KIIELEKSKPNPDLPTEREI 442
Q+ E +R+ +L+E+ E E LQD +E+ +A KI E K D TERE+
Sbjct: 1071 QQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREV 1130
Query: 443 -DLWAELQATKETLRVTEDEVTTCKRE---KESEN-KIGIQQKLAAELL----NKEEIIG 493
DL + + R ++ E T R+ E EN K+ +Q+K+ E++ E +
Sbjct: 1131 SDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKV-REIVRPDPKAESEVA 1189
Query: 494 KMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ---DLQQEIM 550
++++ E + + E+++ Y+ + L+ + + + I Y+ ++++E+
Sbjct: 1190 NLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQ 1249
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSR 610
L+ +++D E + + +E+ Q K+++ Q + ++ +E++ ++ +T++
Sbjct: 1250 RLREEIVDKTRLIERCDLEIYQLKKEI-QALKDTKPQVQTKEVVQEILQFQEDPQTKE-- 1306
Query: 611 ELAALQQDLEHRMRIVDEVNKQIAAKADEI----QELFATLEN-KQQQIHRLEK 659
E+A+L+ L + ++ ++ A++ ++I +EL E QQ++ R E+
Sbjct: 1307 EVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEE 1360
Score = 62.5 bits (145), Expect = 5e-09
Identities = 98/433 (22%), Positives = 192/433 (44%), Gaps = 37/433 (8%)
Query: 228 LRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTR 287
LRQ E V + ++ R +S +A + +R ELDEE + ++ ++ +T+ ++ R
Sbjct: 867 LRQQPEVE-VTHETLQRNRPDSGVEEAWK-IRKELDEETERRRQLENEVKSTQEEIWTLR 924
Query: 288 NRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLKTGEVTTS 344
N+ + +E + +LE+ +Q + L K L+E L+ ++
Sbjct: 925 NQGPQESVVRKEVLKKVPD-----PVLEESFQQLQRTLAEEQHKNQLLQEELEALQLQLR 979
Query: 345 QLIQQ-RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
L Q+ RD Q V++ +IE Q + QL E+L+ AL+ Q + E+ L
Sbjct: 980 ALEQETRDGGQEYVVKEVLRIEPDRAQ-ADEVLQLREELE----ALRRQKGAREAEVLLL 1034
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
++ L + ++ +E K+ E E K D E E E ++ LR ++E
Sbjct: 1035 QQRVAALAEEKSRAQE---KVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEEL 1091
Query: 464 T-----CKR-EKE---SENKIGIQQKLAAEL-LNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ KR EKE +E KI +++ L E E + + Q + + ++++
Sbjct: 1092 SFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREK 1151
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILA 571
+ + + L+ N + QE I D + E+ +L+++L++ + E L
Sbjct: 1152 TELLRKIWALEEENAKVV-VQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLR 1210
Query: 572 KKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQQDLEHRMRIVDEVN 630
ELE R + ++++E V+K K + E +EL L++++ + R+++ +
Sbjct: 1211 SYQSELEA----LRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCD 1266
Query: 631 KQIAAKADEIQEL 643
+I EIQ L
Sbjct: 1267 LEIYQLKKEIQAL 1279
Score = 41.5 bits (93), Expect = 0.010
Identities = 58/294 (19%), Positives = 127/294 (43%), Gaps = 23/294 (7%)
Query: 239 IDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT---RNRVAKMDK 295
I +++ + + + + ++E+ ++ +T + + +E Q +Q R R A ++
Sbjct: 1276 IQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERER-ASQEE 1334
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
Q+ E ++ + V E ++E L A A ES+ +L + LQ
Sbjct: 1335 QIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQR 1394
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLK--QTKRALQEQCEITKREIELKERTETELQDS 413
E ++Q+E+L + + A ++ E +++ Q + A EQ E RE + QD
Sbjct: 1395 RRTELERQLEELE-RERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDP 1453
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESEN 473
+ A E + ++LE+ + L L EL+ + L E + E +
Sbjct: 1454 QQAREHALLR-LQLEEEQHRRQL-------LEGELETLRRKLAALE--------KAEVKE 1497
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
K+ + + + E + E+ I +++ E ++ + + +V + E + +L+ HN
Sbjct: 1498 KVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHN 1551
Score = 34.3 bits (75), Expect = 1.5
Identities = 46/214 (21%), Positives = 95/214 (44%), Gaps = 13/214 (6%)
Query: 209 HERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEIRELRSESENTKALEEMRHELDEERT 267
H R+ L E L R++A L + +V+ + V+ + ++ + ++E + ++ ++ L+EE
Sbjct: 1471 HRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTE--QEIQRLKSSLEEESR 1528
Query: 268 AKLAIKEKLTTTESQLRQTRNRVAKMDKQ---LREAEASITSLTGTVKMLEDQSRQKEVQ 324
+K + +++ E++L + +K K+ LRE + L LE + Q E+
Sbjct: 1529 SKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKL-QLERENLQLETRRLQSEIN 1587
Query: 325 LEA-RARKLRESLKTGEVTTS-----QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL 378
+ A R LR T L ++ D L+ + +I++L + S +
Sbjct: 1588 MAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKR 1647
Query: 379 EEDLKQTKRALQEQCEITKREIELKERTETELQD 412
E+ +R++ T RE+ +E L D
Sbjct: 1648 EQRENHLRRSIVVIHPDTGRELSPEEAHRAGLID 1681
>AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.
Length = 1710
Score = 68.1 bits (159), Expect = 1e-10
Identities = 106/464 (22%), Positives = 209/464 (45%), Gaps = 46/464 (9%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEE--MRHELDEERTAKLAIKEKLTTTESQL 283
+ L Q V+ RN D R+L S +N + L++ + + L +++ ++A K K+ + S
Sbjct: 849 SNLNQVVQERN---DAQRQL-SREQNARMLQDGILTNHLSKQKEIEMAQK-KMNSENSHS 903
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQ----LEARARKLRESLKTG 339
+ ++ + L+E A + T+K + +K + ++ + L++++K
Sbjct: 904 HEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQN 963
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL------QEQC 393
E T +Q I Q + + + + K + ++LE +++ L ++Q
Sbjct: 964 EETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQS 1023
Query: 394 EITKREIEL---KERTE-TELQDSRNA-IEELQA--KIIELEKSKPNPDLPTEREIDLWA 446
E +KRE+EL + R E + LQD N + L+ +I+ + K L EI+
Sbjct: 1024 ETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKL-NSLEIEFHH 1082
Query: 447 ELQATKE-TL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL 502
A +E TL RV +D T + KE E K +Q + + K+E + + Q +
Sbjct: 1083 TRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQS- 1141
Query: 503 IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+N+ L +Q + +T+ N Q+ + I Q LQ E K LL + R
Sbjct: 1142 -ENMLLRQQ----LDDAHNKADNKEKTVINIQDQFHAI-VQKLQAE--SEKQSLL-LEER 1192
Query: 563 NEEL-SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE-TEQSRELAA-----L 615
N+EL SE K+++ + +++ + + V ++++EL + LK + +E S E+ + L
Sbjct: 1193 NKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINL 1252
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ + + + + ++ Q+ D E E Q +LEK
Sbjct: 1253 EDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEK 1296
Score = 50.8 bits (116), Expect = 2e-05
Identities = 102/549 (18%), Positives = 229/549 (41%), Gaps = 64/549 (11%)
Query: 120 VAQLYRDAIASSTPENALELL-----DETMPIENIIKYPKTNLTVNQDQTDGDILEHLSR 174
+A D S T + LEL DE +++ + + +NL N + + + S+
Sbjct: 1013 LAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESK 1072
Query: 175 YNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVET 234
N E L+ + DLS+ C + + + E K+ + +
Sbjct: 1073 LNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKE----MEQKYQNEQVKVNKYIGK 1128
Query: 235 RNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLR-QTRNRVAK 292
+ + + + +L+SE+ + L++ ++ D + + I+++ +L+ ++ +
Sbjct: 1129 QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL 1188
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
++++ +E + L E++ ++EV + ++L ++LK ++ + L
Sbjct: 1189 LEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASL------ 1242
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
+ + + + Q L++ L Q + LQE + + E+ +QD
Sbjct: 1243 ---------EVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEK----MQD 1289
Query: 413 SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+ +E+ AK+ + ++++D ELQ ++EDE K+ E +
Sbjct: 1290 HKQKLEKDNAKL----------KVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELK 1339
Query: 473 NKI--GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ + Q++ + + EI G + + KLNE + ++ + DL+ ++
Sbjct: 1340 QSLECNLDQEMKKNVELEREITGFKNLLK---MTRKKLNEYENGEF-SFHGDLKT-SQFE 1394
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-SEILAKK--DQELEQQDKNSRGQ 587
+ Q + DL E+ K L + +N+ L E+L+ K ++ E+ KN +
Sbjct: 1395 MDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKK-- 1452
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI----QEL 643
K+ +E+IN+ + E R + L Q +++ I + ++IA K E+ Q
Sbjct: 1453 ----KLEQEVINLRSHIE----RNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQ 1504
Query: 644 FATLENKQQ 652
A+ EN +Q
Sbjct: 1505 AASQENLEQ 1513
Score = 48.4 bits (110), Expect = 9e-05
Identities = 83/419 (19%), Positives = 173/419 (41%), Gaps = 26/419 (6%)
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
++ EL E + K ++ + E +L R + + +++ R A+ + ++ E+Q
Sbjct: 763 LQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQ 822
Query: 318 SRQK-EV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV---LECKQQIEKLTVQH 371
R++ EV QLE + L L+T + +Q++Q+R+ Q ++ + + + H
Sbjct: 823 YRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNH 882
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK 431
S +++E K+ E K + E+ R I+ ++ + E EK K
Sbjct: 883 LSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEK-K 941
Query: 432 PNPDLP--TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE 489
DL E+ DL ++ +ETL T + +EN + + KL E +KE
Sbjct: 942 CFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAM-LNSKLENEKQSKE 1000
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GIS-----YQ 543
+ +++ L I +Q + Q + Q+ N +S +
Sbjct: 1001 RLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNE 1060
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLK 602
L Q++ + KL + + L +K LE+ K+ S+ Q ++ +E+ +
Sbjct: 1061 ILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQM----KEMEQKYQ 1116
Query: 603 NKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF----ATLENKQQQIHRL 657
N++ + ++ + Q+ +E R+ + N + + D+ T+ N Q Q H +
Sbjct: 1117 NEQVKVNKYIGK-QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAI 1174
Score = 41.5 bits (93), Expect = 0.010
Identities = 81/363 (22%), Positives = 155/363 (42%), Gaps = 61/363 (16%)
Query: 169 LEHLSRYN----DQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVRE 224
LE SRY D+ +L L +++ Q ++A + T+ + C E+ + + L ++
Sbjct: 1242 LEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVR--CAEK--MQDHKQKLEKD 1297
Query: 225 VAKLRQDVETRNVMIDEIRE-------LRSESENTKALEEMRHEL----DEERTAKLAIK 273
AKL+ V+ + I+E+++ E E K L E++ L D+E + ++
Sbjct: 1298 NAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELE 1357
Query: 274 EKLTTTESQLRQTRNRVAK------------------MDKQLREAEASITSLTGTVKMLE 315
++T ++ L+ TR ++ + MD Q+ + + I LT +
Sbjct: 1358 REITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAEL---- 1413
Query: 316 DQSRQKEVQLEARARKLRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTV--- 369
+ + K + L+ + + L+E S+KT + +L + + L+ EV+ + IE+ V
Sbjct: 1414 ETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELG 1473
Query: 370 ---QHKSAI-----QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
Q+K I Q++ E LK+ LQ Q + + +E ++ EL+
Sbjct: 1474 QVKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQM----ELR 1529
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K +E E SK + +L Q E L+V + + K K +E + KL
Sbjct: 1530 IKDLESELSKIKTSQEDFNKTELEKYKQLYLEELKVRKS--LSSKLTKTNERLAEVNTKL 1587
Query: 482 AAE 484
E
Sbjct: 1588 LVE 1590
>AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens
cDNA FLJ46736 fis, clone TRACH3020769, weakly similar
to Myosin heavy chain, nonmuscle type B. ).
Length = 1080
Score = 68.1 bits (159), Expect = 1e-10
Identities = 106/464 (22%), Positives = 209/464 (45%), Gaps = 46/464 (9%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEE--MRHELDEERTAKLAIKEKLTTTESQL 283
+ L Q V+ RN D R+L S +N + L++ + + L +++ ++A K K+ + S
Sbjct: 406 SNLNQVVQERN---DAQRQL-SREQNARMLQDGILTNHLSKQKEIEMAQK-KMNSENSHS 460
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQ----LEARARKLRESLKTG 339
+ ++ + L+E A + T+K + +K + ++ + L++++K
Sbjct: 461 HEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQN 520
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL------QEQC 393
E T +Q I Q + + + + K + ++LE +++ L ++Q
Sbjct: 521 EETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQS 580
Query: 394 EITKREIEL---KERTE-TELQDSRNA-IEELQA--KIIELEKSKPNPDLPTEREIDLWA 446
E +KRE+EL + R E + LQD N + L+ +I+ + K L EI+
Sbjct: 581 ETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKL-NSLEIEFHH 639
Query: 447 ELQATKE-TL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL 502
A +E TL RV +D T + KE E K +Q + + K+E + + Q +
Sbjct: 640 TRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQS- 698
Query: 503 IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+N+ L +Q + +T+ N Q+ + I Q LQ E K LL + R
Sbjct: 699 -ENMLLRQQ----LDDAHNKADNKEKTVINIQDQFHAI-VQKLQAE--SEKQSLL-LEER 749
Query: 563 NEEL-SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE-TEQSRELAA-----L 615
N+EL SE K+++ + +++ + + V ++++EL + LK + +E S E+ + L
Sbjct: 750 NKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINL 809
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ + + + + ++ Q+ D E E Q +LEK
Sbjct: 810 EDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEK 853
Score = 59.3 bits (137), Expect = 5e-08
Identities = 96/437 (21%), Positives = 191/437 (43%), Gaps = 48/437 (10%)
Query: 249 SENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLT 308
S+ ++EM + E+ K + E +L Q ++ + +QL +A +
Sbjct: 659 SQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKE 718
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
TV ++DQ +L+A + K +SL E +LI + + L+ E + Q E
Sbjct: 719 KTVINIQDQFHAIVQKLQAESEK--QSLLLEE-RNKELISECNHLK----ERQYQYENEK 771
Query: 369 VQHKSAIQQLEEDLKQT--KRALQE-QCEITKR-EIELKERTET---ELQDSRNAIEELQ 421
+ + ++QL+++L T K+++ E E+T R I L++ T+ +L RN ++E Q
Sbjct: 772 AEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQ 831
Query: 422 AKIIE--------------LEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKR 467
+ E LEK + ++++D ELQ ++EDE K+
Sbjct: 832 DRHTEAVRCAEKMQDHKQKLEKDNAKLKVTIKKQMDKIEELQKNLLNANLSEDEKEQLKK 891
Query: 468 EKESENKI--GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQA 525
E + + + Q++ + + EI G + + KLNE + ++ + DL+
Sbjct: 892 LMELKQSLECNLGQEMKKNVELEREITGFKNLLK---MTRKKLNEYENGEF-SFHGDLKT 947
Query: 526 HNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-SEILAKK--DQELEQQDK 582
++ + Q + DL E+ K L + +N+ L E+L+ K ++ E+ K
Sbjct: 948 -SQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQK 1006
Query: 583 NSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQE 642
N + K+ +E+IN+ + E R + L Q +++ I + ++IA K E+
Sbjct: 1007 NKK------KLEQEVINLRSHIE----RNMVELGQVKQYKQEIEERARQEIAEKLKEVNL 1056
Query: 643 LFATLENKQQQIHRLEK 659
Q+ + +L +
Sbjct: 1057 FLQAQAASQENLEQLRE 1073
Score = 48.4 bits (110), Expect = 9e-05
Identities = 83/419 (19%), Positives = 173/419 (41%), Gaps = 26/419 (6%)
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
++ EL E + K ++ + E +L R + + +++ R A+ + ++ E+Q
Sbjct: 320 LQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQ 379
Query: 318 SRQK-EV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV---LECKQQIEKLTVQH 371
R++ EV QLE + L L+T + +Q++Q+R+ Q ++ + + + H
Sbjct: 380 YRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNH 439
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK 431
S +++E K+ E K + E+ R I+ ++ + E EK K
Sbjct: 440 LSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEK-K 498
Query: 432 PNPDLP--TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE 489
DL E+ DL ++ +ETL T + +EN + + KL E +KE
Sbjct: 499 CFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAM-LNSKLENEKQSKE 557
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GIS-----YQ 543
+ +++ L I +Q + Q + Q+ N +S +
Sbjct: 558 RLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNE 617
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLK 602
L Q++ + KL + + L +K LE+ K+ S+ Q ++ +E+ +
Sbjct: 618 ILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQM----KEMEQKYQ 673
Query: 603 NKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF----ATLENKQQQIHRL 657
N++ + ++ + Q+ +E R+ + N + + D+ T+ N Q Q H +
Sbjct: 674 NEQVKVNKYIGK-QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAI 731
Score = 39.5 bits (88), Expect = 0.039
Identities = 55/278 (19%), Positives = 125/278 (44%), Gaps = 24/278 (8%)
Query: 159 VNQDQTDGDILEHLSRYNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVG 218
+N + D+ + L + +Q E ++ T+A + D ++ + L
Sbjct: 807 INLEDETQDLKKKLGQIRNQLQEA----QDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTI 862
Query: 219 EALVREVAKLRQDVETRNVMIDEIRELRSESENTKALE-----EMRHELDEERTAKLAIK 273
+ + ++ +L++++ N+ DE +L+ E ++LE EM+ ++ ER K
Sbjct: 863 KKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLGQEMKKNVELEREIT-GFK 921
Query: 274 EKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVK-MLEDQSRQKE------VQLE 326
L T +L + N L+ ++ + +K ++D + + E + L+
Sbjct: 922 NLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLD 981
Query: 327 ARARKLRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLK 383
+ + L+E S+KT + +L + + L+ EV+ + IE+ V+ ++Q +++++
Sbjct: 982 TKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVE-LGQVKQYKQEIE 1040
Query: 384 QTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
+ RA QE E K E+ L + + Q++ + E Q
Sbjct: 1041 E--RARQEIAEKLK-EVNLFLQAQAASQENLEQLREKQ 1075
Score = 37.5 bits (83), Expect = 0.16
Identities = 54/292 (18%), Positives = 126/292 (43%), Gaps = 13/292 (4%)
Query: 122 QLYRDAIASSTPENALELLDETMPIENIIKYPKTNLTVNQDQTDGDILEHLSRYNDQGFE 181
Q +A T + L DET ++ + + L QD+ + + + D +
Sbjct: 792 QSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHT-EAVRCAEKMQDHKQK 850
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVETR-NVMID 240
L +LK + ++ + +L K + L + ++++ +L+Q +E +
Sbjct: 851 LEKDNAKLKVTIKKQMDKIEELQKNLLNAN--LSEDEKEQLKKLMELKQSLECNLGQEMK 908
Query: 241 EIRELRSESENTKALEEM-RHELDEERTAKLAIKEKLTTTES----QLRQTRNRVAKMDK 295
+ EL E K L +M R +L+E + + L T++ Q+ + ++++ +
Sbjct: 909 KNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTA 968
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
+L A + L ++L+++ + ++ + KL+++ K E ++I R ++
Sbjct: 969 ELETAGSKCLHLDTKNQILQEELLSMKT-VQKKCEKLQKNKKKLE---QEVINLRSHIER 1024
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTE 407
++E Q + + A Q++ E LK+ LQ Q + +L+E+ +
Sbjct: 1025 NMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQLREKQD 1076
>AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein.
Length = 1261
Score = 68.1 bits (159), Expect = 1e-10
Identities = 72/338 (21%), Positives = 158/338 (46%), Gaps = 24/338 (7%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-----LEEMRHELDEERTAKLAIKEKLTTTE 280
AKL++ +E + +++++E +S+ + +A L+E R E E AK E++ T
Sbjct: 226 AKLKE-LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 284
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+ +A +DK++ E A SL V+ L+++ + LE ++ E G
Sbjct: 285 DAIE-----MATLDKEMAEERAE--SLQQEVEALKERVDELTTDLEILKAEIEEKGSDGA 337
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI 400
++ QL +Q + A + + ++ L+ K +L++ +++ + L E+ +++
Sbjct: 338 ASSYQL-KQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL----EVVRQQ- 391
Query: 401 ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
+ER + EL + + I+EL+ ++ ++ ++ T+R ++L +++ +ET V +
Sbjct: 392 --RERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRET--VGDL 447
Query: 461 EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYV 520
E ++ EN + +L +L + + Q + + + +Q + +Y Q
Sbjct: 448 EAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLT 507
Query: 521 RDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD 558
LQ NR + N QE+ + Q E D K+K +
Sbjct: 508 AHLQDVNRELTNQQEA-SVERQQQPPPETFDFKIKFAE 544
Score = 62.1 bits (144), Expect = 6e-09
Identities = 84/355 (23%), Positives = 159/355 (44%), Gaps = 32/355 (9%)
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
G V L S+++E L A+ R L E L+T +L + D + + LE K +I+
Sbjct: 188 GAVPPLPSPSKEEE-GLRAQVRDLEEKLET-----LRLKRAEDKAKLKELE-KHKIQLEQ 240
Query: 369 VQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
VQ KS +Q+ + DL+ R L+E + K +E KER E+ D+ +AIE + L
Sbjct: 241 VQEWKSKMQEQQADLQ---RRLKEARKEAKEALEAKERYMEEMADTADAIE-----MATL 292
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
+K ++ ER L E++A KE + ++ K E E + G + L
Sbjct: 293 DK-----EMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLE 347
Query: 488 KEEI-IGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQDL 545
++ + ++ R+L + K K+ + E+ ++L+ + QE
Sbjct: 348 EQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQE-----ELSQA 402
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
+ I +LK + +D EE+ E+L ++ LE++ + R ++ E+ + L+
Sbjct: 403 ESTIDELK-EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENA 461
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
E E L++ L+ V E K++ A + + + T++ +Q L+ +
Sbjct: 462 RETELE---LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 513
Score = 34.7 bits (76), Expect = 1.1
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 18/201 (8%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHER--RTLIAVGEALVREVAKLRQDVETRNVMI 239
L AL EL +A + + S C + LI+ L + + D E
Sbjct: 845 LVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTMNKLATAMQEGEYDAERPPSKP 904
Query: 240 D--EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL 297
E+R +E T A E + +L++ T +K+ L +L + R++ ++K+L
Sbjct: 905 PPVELRAAALRAEITDA-EGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKL 963
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
A K +++ + + +LE LR+ K E T L D L+AE
Sbjct: 964 DSA----------AKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEK 1013
Query: 358 LECKQQIEKLTVQHKSAIQQL 378
E KQ +L Q K I+ L
Sbjct: 1014 AELKQ---RLNSQSKRTIEGL 1031
>AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform
protein.
Length = 1144
Score = 68.1 bits (159), Expect = 1e-10
Identities = 72/338 (21%), Positives = 158/338 (46%), Gaps = 24/338 (7%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-----LEEMRHELDEERTAKLAIKEKLTTTE 280
AKL++ +E + +++++E +S+ + +A L+E R E E AK E++ T
Sbjct: 109 AKLKE-LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 167
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+ +A +DK++ E A SL V+ L+++ + LE ++ E G
Sbjct: 168 DAIE-----MATLDKEMAEERAE--SLQQEVEALKERVDELTTDLEILKAEIEEKGSDGA 220
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI 400
++ QL +Q + A + + ++ L+ K +L++ +++ + L E+ +++
Sbjct: 221 ASSYQL-KQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL----EVVRQQ- 274
Query: 401 ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
+ER + EL + + I+EL+ ++ ++ ++ T+R ++L +++ +ET V +
Sbjct: 275 --RERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRET--VGDL 330
Query: 461 EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYV 520
E ++ EN + +L +L + + Q + + + +Q + +Y Q
Sbjct: 331 EAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLT 390
Query: 521 RDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD 558
LQ NR + N QE+ + Q E D K+K +
Sbjct: 391 AHLQDVNRELTNQQEA-SVERQQQPPPETFDFKIKFAE 427
Score = 62.1 bits (144), Expect = 6e-09
Identities = 84/355 (23%), Positives = 159/355 (44%), Gaps = 32/355 (9%)
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
G V L S+++E L A+ R L E L+T +L + D + + LE K +I+
Sbjct: 71 GAVPPLPSPSKEEE-GLRAQVRDLEEKLET-----LRLKRAEDKAKLKELE-KHKIQLEQ 123
Query: 369 VQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
VQ KS +Q+ + DL+ R L+E + K +E KER E+ D+ +AIE + L
Sbjct: 124 VQEWKSKMQEQQADLQ---RRLKEARKEAKEALEAKERYMEEMADTADAIE-----MATL 175
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
+K ++ ER L E++A KE + ++ K E E + G + L
Sbjct: 176 DK-----EMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLE 230
Query: 488 KEEI-IGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQDL 545
++ + ++ R+L + K K+ + E+ ++L+ + QE
Sbjct: 231 EQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQE-----ELSQA 285
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
+ I +LK + +D EE+ E+L ++ LE++ + R ++ E+ + L+
Sbjct: 286 ESTIDELK-EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENA 344
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
E E L++ L+ V E K++ A + + + T++ +Q L+ +
Sbjct: 345 RETELE---LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 396
Score = 34.7 bits (76), Expect = 1.1
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 18/201 (8%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHER--RTLIAVGEALVREVAKLRQDVETRNVMI 239
L AL EL +A + + S C + LI+ L + + D E
Sbjct: 728 LVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTMNKLATAMQEGEYDAERPPSKP 787
Query: 240 D--EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL 297
E+R +E T A E + +L++ T +K+ L +L + R++ ++K+L
Sbjct: 788 PPVELRAAALRAEITDA-EGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKL 846
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
A K +++ + + +LE LR+ K E T L D L+AE
Sbjct: 847 DSA----------AKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEK 896
Query: 358 LECKQQIEKLTVQHKSAIQQL 378
E KQ +L Q K I+ L
Sbjct: 897 AELKQ---RLNSQSKRTIEGL 914
>AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform
protein.
Length = 1278
Score = 68.1 bits (159), Expect = 1e-10
Identities = 72/338 (21%), Positives = 158/338 (46%), Gaps = 24/338 (7%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-----LEEMRHELDEERTAKLAIKEKLTTTE 280
AKL++ +E + +++++E +S+ + +A L+E R E E AK E++ T
Sbjct: 243 AKLKE-LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 301
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+ +A +DK++ E A SL V+ L+++ + LE ++ E G
Sbjct: 302 DAIE-----MATLDKEMAEERAE--SLQQEVEALKERVDELTTDLEILKAEIEEKGSDGA 354
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI 400
++ QL +Q + A + + ++ L+ K +L++ +++ + L E+ +++
Sbjct: 355 ASSYQL-KQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL----EVVRQQ- 408
Query: 401 ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
+ER + EL + + I+EL+ ++ ++ ++ T+R ++L +++ +ET V +
Sbjct: 409 --RERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRET--VGDL 464
Query: 461 EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYV 520
E ++ EN + +L +L + + Q + + + +Q + +Y Q
Sbjct: 465 EAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLT 524
Query: 521 RDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD 558
LQ NR + N QE+ + Q E D K+K +
Sbjct: 525 AHLQDVNRELTNQQEA-SVERQQQPPPETFDFKIKFAE 561
Score = 62.1 bits (144), Expect = 6e-09
Identities = 84/355 (23%), Positives = 159/355 (44%), Gaps = 32/355 (9%)
Query: 309 GTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLT 368
G V L S+++E L A+ R L E L+T +L + D + + LE K +I+
Sbjct: 205 GAVPPLPSPSKEEE-GLRAQVRDLEEKLET-----LRLKRAEDKAKLKELE-KHKIQLEQ 257
Query: 369 VQH-KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIEL 427
VQ KS +Q+ + DL+ R L+E + K +E KER E+ D+ +AIE + L
Sbjct: 258 VQEWKSKMQEQQADLQ---RRLKEARKEAKEALEAKERYMEEMADTADAIE-----MATL 309
Query: 428 EKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLN 487
+K ++ ER L E++A KE + ++ K E E + G + L
Sbjct: 310 DK-----EMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLE 364
Query: 488 KEEI-IGKMQIQTRELIKNIKLNEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQDL 545
++ + ++ R+L + K K+ + E+ ++L+ + QE
Sbjct: 365 EQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQE-----ELSQA 419
Query: 546 QQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE 605
+ I +LK + +D EE+ E+L ++ LE++ + R ++ E+ + L+
Sbjct: 420 ESTIDELK-EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENA 478
Query: 606 TEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
E E L++ L+ V E K++ A + + + T++ +Q L+ +
Sbjct: 479 RETELE---LREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 530
Score = 34.7 bits (76), Expect = 1.1
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 18/201 (8%)
Query: 182 LCGALRELKTQAEDAVNTVTDLSKRACHER--RTLIAVGEALVREVAKLRQDVETRNVMI 239
L AL EL +A + + S C + LI+ L + + D E
Sbjct: 862 LVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTMNKLATAMQEGEYDAERPPSKP 921
Query: 240 D--EIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQL 297
E+R +E T A E + +L++ T +K+ L +L + R++ ++K+L
Sbjct: 922 PPVELRAAALRAEITDA-EGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKL 980
Query: 298 REAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV 357
A K +++ + + +LE LR+ K E T L D L+AE
Sbjct: 981 DSA----------AKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEK 1030
Query: 358 LECKQQIEKLTVQHKSAIQQL 378
E KQ +L Q K I+ L
Sbjct: 1031 AELKQ---RLNSQSKRTIEGL 1048
>AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 68.1 bits (159), Expect = 1e-10
Identities = 102/474 (21%), Positives = 223/474 (47%), Gaps = 44/474 (9%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
RR L ++ E+ LR +V+ E+ + + ++ ++++ L EE+
Sbjct: 906 RRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQ 965
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARA 329
++E+L + QLR ++++ R+ + +++ D+++ EV QL
Sbjct: 966 LLQEELEALQLQLR-------ALEQETRDGGQEYV-VKEVLRIEPDRAQADEVLQLREEL 1017
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL 389
LR K L+QQR + AE E + EK+T + + +L+ D Q +
Sbjct: 1018 EALRRQ-KGAREAEVLLLQQRVAALAE--EKSRAQEKVT---EKEVVKLQND-PQLEAEY 1070
Query: 390 QEQCEITKREIELKERTETE---LQDSRNAIEELQA----KIIELEKSKPNPDLPTEREI 442
Q+ E +R+ +L+E+ E E LQD +E+ +A KI E K D TERE+
Sbjct: 1071 QQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREV 1130
Query: 443 -DLWAELQATKETLRVTEDEVTTCKRE---KESEN-KIGIQQKLAAELL----NKEEIIG 493
DL + + R ++ E T R+ E EN K+ +Q+K+ E++ E +
Sbjct: 1131 SDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKV-REIVRPDPKAESEVA 1189
Query: 494 KMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ---DLQQEIM 550
++++ E + + E+++ Y+ + L+ + + + I Y+ ++++E+
Sbjct: 1190 NLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQ 1249
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSR 610
L+ +++D E + + +E+ Q K+++ Q + ++ +E++ ++ +T++
Sbjct: 1250 RLREEIVDKTRLIERCDLEIYQLKKEI-QALKDTKPQVQTKEVVQEILQFQEDPQTKE-- 1306
Query: 611 ELAALQQDLEHRMRIVDEVNKQIAAKADEI----QELFATLEN-KQQQIHRLEK 659
E+A+L+ L + ++ ++ A++ ++I +EL E QQ++ R E+
Sbjct: 1307 EVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEE 1360
Score = 62.5 bits (145), Expect = 5e-09
Identities = 98/433 (22%), Positives = 192/433 (44%), Gaps = 37/433 (8%)
Query: 228 LRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTR 287
LRQ E V + ++ R +S +A + +R ELDEE + ++ ++ +T+ ++ R
Sbjct: 867 LRQQPEVE-VTHETLQRNRPDSGVEEAWK-IRKELDEETERRRQLENEVKSTQEEIWTLR 924
Query: 288 NRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLKTGEVTTS 344
N+ + +E + +LE+ +Q + L K L+E L+ ++
Sbjct: 925 NQGPQESVVRKEVLKKVPD-----PVLEESFQQLQRTLAEEQHKNQLLQEELEALQLQLR 979
Query: 345 QLIQQ-RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
L Q+ RD Q V++ +IE Q + QL E+L+ AL+ Q + E+ L
Sbjct: 980 ALEQETRDGGQEYVVKEVLRIEPDRAQ-ADEVLQLREELE----ALRRQKGAREAEVLLL 1034
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
++ L + ++ +E K+ E E K D E E E ++ LR ++E
Sbjct: 1035 QQRVAALAEEKSRAQE---KVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEEL 1091
Query: 464 T-----CKR-EKE---SENKIGIQQKLAAEL-LNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ KR EKE +E KI +++ L E E + + Q + + ++++
Sbjct: 1092 SFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREK 1151
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILA 571
+ + + L+ N + QE I D + E+ +L+++L++ + E L
Sbjct: 1152 TELLRKIWALEEENAKVV-VQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLR 1210
Query: 572 KKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQQDLEHRMRIVDEVN 630
ELE R + ++++E V+K K + E +EL L++++ + R+++ +
Sbjct: 1211 SYQSELEA----LRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCD 1266
Query: 631 KQIAAKADEIQEL 643
+I EIQ L
Sbjct: 1267 LEIYQLKKEIQAL 1279
Score = 41.9 bits (94), Expect = 0.007
Identities = 75/389 (19%), Positives = 167/389 (42%), Gaps = 32/389 (8%)
Query: 239 IDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT---RNRVAKMDK 295
I +++ + + + + ++E+ ++ +T + + +E Q +Q R R A ++
Sbjct: 1276 IQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERER-ASQEE 1334
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
Q+ E ++ + V E ++E L A A ES+ +L + LQ
Sbjct: 1335 QIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQR 1394
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLK--QTKRALQEQCEITKREIELKERTETELQDS 413
E ++Q+E+L + + A ++ E +++ Q + A EQ E RE + QD
Sbjct: 1395 RRTELERQLEELE-RERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDP 1453
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESEN 473
+ A E + ++LE+ + L L EL+ + L E + E +
Sbjct: 1454 QQAREHALLR-LQLEEEQHRRQL-------LEGELETLRRKLAALE--------KAEVKE 1497
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
K+ + + + E + E+ I +++ E ++ + + +V + E + +L+ HN +
Sbjct: 1498 KVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKE 1557
Query: 534 QESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQ---DKNSRGQARV 590
+ +++ LQ E +L+++ R + + A + ++L D + +R+
Sbjct: 1558 LDFLREENHK-LQLERQNLQLE----TRRLQSEINMAATETRDLRNMTVADSGTNHDSRL 1612
Query: 591 IKIREELINVLKNKETEQSRELAALQQDL 619
+ EL + LK ++ E+ LQ+ L
Sbjct: 1613 WSLEREL-DDLKRLSKDKDLEIDELQKRL 1640
>AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 68.1 bits (159), Expect = 1e-10
Identities = 102/474 (21%), Positives = 223/474 (47%), Gaps = 44/474 (9%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
RR L ++ E+ LR +V+ E+ + + ++ ++++ L EE+
Sbjct: 906 RRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQ 965
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARA 329
++E+L + QLR ++++ R+ + +++ D+++ EV QL
Sbjct: 966 LLQEELEALQLQLR-------ALEQETRDGGQEYV-VKEVLRIEPDRAQADEVLQLREEL 1017
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL 389
LR K L+QQR + AE E + EK+T + + +L+ D Q +
Sbjct: 1018 EALRRQ-KGAREAEVLLLQQRVAALAE--EKSRAQEKVT---EKEVVKLQND-PQLEAEY 1070
Query: 390 QEQCEITKREIELKERTETE---LQDSRNAIEELQA----KIIELEKSKPNPDLPTEREI 442
Q+ E +R+ +L+E+ E E LQD +E+ +A KI E K D TERE+
Sbjct: 1071 QQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREV 1130
Query: 443 -DLWAELQATKETLRVTEDEVTTCKRE---KESEN-KIGIQQKLAAELL----NKEEIIG 493
DL + + R ++ E T R+ E EN K+ +Q+K+ E++ E +
Sbjct: 1131 SDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKV-REIVRPDPKAESEVA 1189
Query: 494 KMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ---DLQQEIM 550
++++ E + + E+++ Y+ + L+ + + + I Y+ ++++E+
Sbjct: 1190 NLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQ 1249
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSR 610
L+ +++D E + + +E+ Q K+++ Q + ++ +E++ ++ +T++
Sbjct: 1250 RLREEIVDKTRLIERCDLEIYQLKKEI-QALKDTKPQVQTKEVVQEILQFQEDPQTKE-- 1306
Query: 611 ELAALQQDLEHRMRIVDEVNKQIAAKADEI----QELFATLEN-KQQQIHRLEK 659
E+A+L+ L + ++ ++ A++ ++I +EL E QQ++ R E+
Sbjct: 1307 EVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEE 1360
Score = 62.5 bits (145), Expect = 5e-09
Identities = 98/433 (22%), Positives = 192/433 (44%), Gaps = 37/433 (8%)
Query: 228 LRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTR 287
LRQ E V + ++ R +S +A + +R ELDEE + ++ ++ +T+ ++ R
Sbjct: 867 LRQQPEVE-VTHETLQRNRPDSGVEEAWK-IRKELDEETERRRQLENEVKSTQEEIWTLR 924
Query: 288 NRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLKTGEVTTS 344
N+ + +E + +LE+ +Q + L K L+E L+ ++
Sbjct: 925 NQGPQESVVRKEVLKKVPD-----PVLEESFQQLQRTLAEEQHKNQLLQEELEALQLQLR 979
Query: 345 QLIQQ-RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
L Q+ RD Q V++ +IE Q + QL E+L+ AL+ Q + E+ L
Sbjct: 980 ALEQETRDGGQEYVVKEVLRIEPDRAQ-ADEVLQLREELE----ALRRQKGAREAEVLLL 1034
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
++ L + ++ +E K+ E E K D E E E ++ LR ++E
Sbjct: 1035 QQRVAALAEEKSRAQE---KVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEEL 1091
Query: 464 T-----CKR-EKE---SENKIGIQQKLAAEL-LNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ KR EKE +E KI +++ L E E + + Q + + ++++
Sbjct: 1092 SFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREK 1151
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILA 571
+ + + L+ N + QE I D + E+ +L+++L++ + E L
Sbjct: 1152 TELLRKIWALEEENAKVV-VQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLR 1210
Query: 572 KKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQQDLEHRMRIVDEVN 630
ELE R + ++++E V+K K + E +EL L++++ + R+++ +
Sbjct: 1211 SYQSELEA----LRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCD 1266
Query: 631 KQIAAKADEIQEL 643
+I EIQ L
Sbjct: 1267 LEIYQLKKEIQAL 1279
Score = 41.9 bits (94), Expect = 0.007
Identities = 75/389 (19%), Positives = 167/389 (42%), Gaps = 32/389 (8%)
Query: 239 IDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT---RNRVAKMDK 295
I +++ + + + + ++E+ ++ +T + + +E Q +Q R R A ++
Sbjct: 1276 IQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERER-ASQEE 1334
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
Q+ E ++ + V E ++E L A A ES+ +L + LQ
Sbjct: 1335 QIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQR 1394
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLK--QTKRALQEQCEITKREIELKERTETELQDS 413
E ++Q+E+L + + A ++ E +++ Q + A EQ E RE + QD
Sbjct: 1395 RRTELERQLEELE-RERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDP 1453
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESEN 473
+ A E + ++LE+ + L L EL+ + L E + E +
Sbjct: 1454 QQAREHALLR-LQLEEEQHRRQL-------LEGELETLRRKLAALE--------KAEVKE 1497
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANC 533
K+ + + + E + E+ I +++ E ++ + + +V + E + +L+ HN +
Sbjct: 1498 KVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKE 1557
Query: 534 QESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQ---DKNSRGQARV 590
+ +++ LQ E +L+++ R + + A + ++L D + +R+
Sbjct: 1558 LDFLREENHK-LQLERQNLQLE----TRRLQSEINMAATETRDLRNMTVADSGTNHDSRL 1612
Query: 591 IKIREELINVLKNKETEQSRELAALQQDL 619
+ EL + LK ++ E+ LQ+ L
Sbjct: 1613 WSLEREL-DDLKRLSKDKDLEIDELQKRL 1640
>AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1
variant protein.
Length = 459
Score = 68.1 bits (159), Expect = 1e-10
Identities = 72/338 (21%), Positives = 158/338 (46%), Gaps = 24/338 (7%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKA-----LEEMRHELDEERTAKLAIKEKLTTTE 280
AKL++ +E + +++++E +S+ + +A L+E R E E AK E++ T
Sbjct: 68 AKLKE-LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTA 126
Query: 281 SQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGE 340
+ +A +DK++ E A SL V+ L+++ + LE ++ E G
Sbjct: 127 DAIE-----MATLDKEMAEERAE--SLQQEVEALKERVDELTTDLEILKAEIEEKGSDGA 179
Query: 341 VTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREI 400
++ QL +Q + A + + ++ L+ K +L++ +++ + L E+ +++
Sbjct: 180 ASSYQL-KQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL----EVVRQQ- 233
Query: 401 ELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTED 460
+ER + EL + + I+EL+ ++ ++ ++ T+R ++L +++ +ET V +
Sbjct: 234 --RERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRET--VGDL 289
Query: 461 EVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYV 520
E ++ EN + +L +L + + Q + + + +Q + +Y Q
Sbjct: 290 EAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLT 349
Query: 521 RDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLD 558
LQ NR + N QE+ + Q E D K+K +
Sbjct: 350 AHLQDVNRELTNQQEA-SVERQQQPPPETFDFKIKFAE 386
Score = 60.9 bits (141), Expect = 1e-08
Identities = 81/344 (23%), Positives = 154/344 (44%), Gaps = 31/344 (9%)
Query: 320 QKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQH-KSAIQQL 378
Q+E L A+ R L E L+T +L + D + + LE K +I+ VQ KS +Q+
Sbjct: 40 QEEEGLRAQVRDLEEKLET-----LRLKRAEDKAKLKELE-KHKIQLEQVQEWKSKMQEQ 93
Query: 379 EEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPT 438
+ DL+ R L+E + K +E KER E+ D+ +AIE + L+K ++
Sbjct: 94 QADLQ---RRLKEARKEAKEALEAKERYMEEMADTADAIE-----MATLDK-----EMAE 140
Query: 439 EREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEI-IGKMQI 497
ER L E++A KE + ++ K E E + G + L ++ + +
Sbjct: 141 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALV 200
Query: 498 QTRELIKNIKLNEQKVIQ-YEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKL 556
+ R+L + K K+ + E+ ++L+ + QE + I +LK +
Sbjct: 201 RMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQE-----ELSQAESTIDELK-EQ 254
Query: 557 LDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQ 616
+D EE+ E+L ++ LE++ + R ++ E+ + L+ E E L+
Sbjct: 255 VDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELE---LR 311
Query: 617 QDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKI 660
+ L+ V E K++ A + + + T++ +Q L+ +
Sbjct: 312 EQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDV 355
Score = 35.9 bits (79), Expect = 0.49
Identities = 44/232 (18%), Positives = 103/232 (44%), Gaps = 12/232 (5%)
Query: 436 LPTEREIDLWAELQATKETLRVTEDEVTTCKREK-ESENKIGIQQKLAAELLNKEEIIGK 494
L T+RE E + + +R E+++ T + ++ E + K+ +K +L +E K
Sbjct: 30 LCTDREASPLQEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSK 89
Query: 495 MQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMD--- 551
MQ Q +L + +K ++ + L+A R + ++ + I L +E+ +
Sbjct: 90 MQEQQADLQRRLKEARKEAKEA------LEAKERYMEEMADTADAIEMATLDKEMAEERA 143
Query: 552 --LKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQS 609
L+ ++ + R +EL+ L E+E++ + + +K EE LK+
Sbjct: 144 ESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMR 203
Query: 610 RELAALQQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEKIV 661
++ +Q+ +++++ N+++ + + L L + I L++ V
Sbjct: 204 DLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQV 255
>AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.
Length = 1715
Score = 68.1 bits (159), Expect = 1e-10
Identities = 106/464 (22%), Positives = 209/464 (45%), Gaps = 46/464 (9%)
Query: 226 AKLRQDVETRNVMIDEIRELRSESENTKALEE--MRHELDEERTAKLAIKEKLTTTESQL 283
+ L Q V+ RN D R+L S +N + L++ + + L +++ ++A K K+ + S
Sbjct: 854 SNLNQVVQERN---DAQRQL-SREQNARMLQDGILTNHLSKQKEIEMAQK-KMNSENSHS 908
Query: 284 RQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQ----LEARARKLRESLKTG 339
+ ++ + L+E A + T+K + +K + ++ + L++++K
Sbjct: 909 HEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQN 968
Query: 340 EVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL------QEQC 393
E T +Q I Q + + + + K + ++LE +++ L ++Q
Sbjct: 969 EETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQS 1028
Query: 394 EITKREIEL---KERTE-TELQDSRNA-IEELQA--KIIELEKSKPNPDLPTEREIDLWA 446
E +KRE+EL + R E + LQD N + L+ +I+ + K L EI+
Sbjct: 1029 ETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKL-NSLEIEFHH 1087
Query: 447 ELQATKE-TL---RVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTREL 502
A +E TL RV +D T + KE E K +Q + + K+E + + Q +
Sbjct: 1088 TRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQS- 1146
Query: 503 IKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHR 562
+N+ L +Q + +T+ N Q+ + I Q LQ E K LL + R
Sbjct: 1147 -ENMLLRQQ----LDDAHNKADNKEKTVINIQDQFHAI-VQKLQAE--SEKQSLL-LEER 1197
Query: 563 NEEL-SEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKE-TEQSRELAA-----L 615
N+EL SE K+++ + +++ + + V ++++EL + LK + +E S E+ + L
Sbjct: 1198 NKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINL 1257
Query: 616 QQDLEHRMRIVDEVNKQIAAKADEIQELFATLENKQQQIHRLEK 659
+ + + + + ++ Q+ D E E Q +LEK
Sbjct: 1258 EDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEK 1301
Score = 50.8 bits (116), Expect = 2e-05
Identities = 102/549 (18%), Positives = 229/549 (41%), Gaps = 64/549 (11%)
Query: 120 VAQLYRDAIASSTPENALELL-----DETMPIENIIKYPKTNLTVNQDQTDGDILEHLSR 174
+A D S T + LEL DE +++ + + +NL N + + + S+
Sbjct: 1018 LAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESK 1077
Query: 175 YNDQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVREVAKLRQDVET 234
N E L+ + DLS+ C + + + E K+ + +
Sbjct: 1078 LNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKE----MEQKYQNEQVKVNKYIGK 1133
Query: 235 RNVMIDEIRELRSESENTKA-LEEMRHELDEERTAKLAIKEKLTTTESQLR-QTRNRVAK 292
+ + + + +L+SE+ + L++ ++ D + + I+++ +L+ ++ +
Sbjct: 1134 QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL 1193
Query: 293 MDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDS 352
++++ +E + L E++ ++EV + ++L ++LK ++ + L
Sbjct: 1194 LEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASL------ 1247
Query: 353 LQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQD 412
+ + + + Q L++ L Q + LQE + + E+ +QD
Sbjct: 1248 ---------EVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEK----MQD 1294
Query: 413 SRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESE 472
+ +E+ AK+ + ++++D ELQ ++EDE K+ E +
Sbjct: 1295 HKQKLEKDNAKL----------KVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELK 1344
Query: 473 NKI--GIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTI 530
+ + Q++ + + EI G + + KLNE + ++ + DL+ ++
Sbjct: 1345 QSLECNLDQEMKKNVELEREITGFKNLLK---MTRKKLNEYENGEF-SFHGDLKT-SQFE 1399
Query: 531 ANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEEL-SEILAKK--DQELEQQDKNSRGQ 587
+ Q + DL E+ K L + +N+ L E+L+ K ++ E+ KN +
Sbjct: 1400 MDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKK-- 1457
Query: 588 ARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEI----QEL 643
K+ +E+IN+ + E R + L Q +++ I + ++IA K E+ Q
Sbjct: 1458 ----KLEQEVINLRSHIE----RNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQ 1509
Query: 644 FATLENKQQ 652
A+ EN +Q
Sbjct: 1510 AASQENLEQ 1518
Score = 48.4 bits (110), Expect = 9e-05
Identities = 83/419 (19%), Positives = 173/419 (41%), Gaps = 26/419 (6%)
Query: 258 MRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQ 317
++ EL E + K ++ + E +L R + + +++ R A+ + ++ E+Q
Sbjct: 768 LQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQ 827
Query: 318 SRQK-EV--QLEARARKLRESLKTGEVTTSQLIQQRDSLQAEV---LECKQQIEKLTVQH 371
R++ EV QLE + L L+T + +Q++Q+R+ Q ++ + + + H
Sbjct: 828 YRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNH 887
Query: 372 KSAIQQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQAKIIELEKSK 431
S +++E K+ E K + E+ R I+ ++ + E EK K
Sbjct: 888 LSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEK-K 946
Query: 432 PNPDLP--TEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKLAAELLNKE 489
DL E+ DL ++ +ETL T + +EN + + KL E +KE
Sbjct: 947 CFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAM-LNSKLENEKQSKE 1005
Query: 490 EIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPN-GIS-----YQ 543
+ +++ L I +Q + Q + Q+ N +S +
Sbjct: 1006 RLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNE 1065
Query: 544 DLQQEIMDLKMKLLDVVHRNEELSEILAKKDQELEQQDKN-SRGQARVIKIREELINVLK 602
L Q++ + KL + + L +K LE+ K+ S+ Q ++ +E+ +
Sbjct: 1066 ILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQM----KEMEQKYQ 1121
Query: 603 NKETEQSRELAALQQDLEHRMRIVDEVNKQIAAKADEIQELF----ATLENKQQQIHRL 657
N++ + ++ + Q+ +E R+ + N + + D+ T+ N Q Q H +
Sbjct: 1122 NEQVKVNKYIGK-QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAI 1179
Score = 41.5 bits (93), Expect = 0.010
Identities = 81/363 (22%), Positives = 155/363 (42%), Gaps = 61/363 (16%)
Query: 169 LEHLSRYN----DQGFELCGALRELKTQAEDAVNTVTDLSKRACHERRTLIAVGEALVRE 224
LE SRY D+ +L L +++ Q ++A + T+ + C E+ + + L ++
Sbjct: 1247 LEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVR--CAEK--MQDHKQKLEKD 1302
Query: 225 VAKLRQDVETRNVMIDEIRE-------LRSESENTKALEEMRHEL----DEERTAKLAIK 273
AKL+ V+ + I+E+++ E E K L E++ L D+E + ++
Sbjct: 1303 NAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELE 1362
Query: 274 EKLTTTESQLRQTRNRVAK------------------MDKQLREAEASITSLTGTVKMLE 315
++T ++ L+ TR ++ + MD Q+ + + I LT +
Sbjct: 1363 REITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAEL---- 1418
Query: 316 DQSRQKEVQLEARARKLRE---SLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTV--- 369
+ + K + L+ + + L+E S+KT + +L + + L+ EV+ + IE+ V
Sbjct: 1419 ETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELG 1478
Query: 370 ---QHKSAI-----QQLEEDLKQTKRALQEQCEITKREIELKERTETELQDSRNAIEELQ 421
Q+K I Q++ E LK+ LQ Q + + +E ++ EL+
Sbjct: 1479 QVKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQM----ELR 1534
Query: 422 AKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESENKIGIQQKL 481
K +E E SK + +L Q E L+V + + K K +E + KL
Sbjct: 1535 IKDLESELSKIKTSQEDFNKTELEKYKQLYLEELKVRKS--LSSKLTKTNERLAEVNTKL 1592
Query: 482 AAE 484
E
Sbjct: 1593 LVE 1595
>AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein.
Length = 1426
Score = 68.1 bits (159), Expect = 1e-10
Identities = 102/474 (21%), Positives = 223/474 (47%), Gaps = 44/474 (9%)
Query: 211 RRTLIAVGEALVREVAKLRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKL 270
RR L ++ E+ LR +V+ E+ + + ++ ++++ L EE+
Sbjct: 576 RRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQ 635
Query: 271 AIKEKLTTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEV-QLEARA 329
++E+L + QLR ++++ R+ + +++ D+++ EV QL
Sbjct: 636 LLQEELEALQLQLR-------ALEQETRDGGQEYV-VKEVLRIEPDRAQADEVLQLREEL 687
Query: 330 RKLRESLKTGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRAL 389
LR K L+QQR + AE E + EK+T + + +L+ D Q +
Sbjct: 688 EALRRQ-KGAREAEVLLLQQRVAALAE--EKSRAQEKVT---EKEVVKLQND-PQLEAEY 740
Query: 390 QEQCEITKREIELKERTETE---LQDSRNAIEELQA----KIIELEKSKPNPDLPTEREI 442
Q+ E +R+ +L+E+ E E LQD +E+ +A KI E K D TERE+
Sbjct: 741 QQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREV 800
Query: 443 -DLWAELQATKETLRVTEDEVTTCKRE---KESEN-KIGIQQKLAAELL----NKEEIIG 493
DL + + R ++ E T R+ E EN K+ +Q+K+ E++ E +
Sbjct: 801 SDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKV-REIVRPDPKAESEVA 859
Query: 494 KMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHNRTIANCQESPNGISYQ---DLQQEIM 550
++++ E + + E+++ Y+ + L+ + + + I Y+ ++++E+
Sbjct: 860 NLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQ 919
Query: 551 DLKMKLLDVVHRNEELSEILAKKDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSR 610
L+ +++D E + + +E+ Q K+++ Q + ++ +E++ ++ +T++
Sbjct: 920 RLREEIVDKTRLIERCDLEIYQLKKEI-QALKDTKPQVQTKEVVQEILQFQEDPQTKE-- 976
Query: 611 ELAALQQDLEHRMRIVDEVNKQIAAKADEI----QELFATLEN-KQQQIHRLEK 659
E+A+L+ L + ++ ++ A++ ++I +EL E QQ++ R E+
Sbjct: 977 EVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEE 1030
Score = 62.5 bits (145), Expect = 5e-09
Identities = 98/433 (22%), Positives = 192/433 (44%), Gaps = 37/433 (8%)
Query: 228 LRQDVETRNVMIDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTR 287
LRQ E V + ++ R +S +A + +R ELDEE + ++ ++ +T+ ++ R
Sbjct: 537 LRQQPEVE-VTHETLQRNRPDSGVEEAWK-IRKELDEETERRRQLENEVKSTQEEIWTLR 594
Query: 288 NRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARK---LRESLKTGEVTTS 344
N+ + +E + +LE+ +Q + L K L+E L+ ++
Sbjct: 595 NQGPQESVVRKEVLKKVPD-----PVLEESFQQLQRTLAEEQHKNQLLQEELEALQLQLR 649
Query: 345 QLIQQ-RDSLQAEVLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITKREIELK 403
L Q+ RD Q V++ +IE Q + QL E+L+ AL+ Q + E+ L
Sbjct: 650 ALEQETRDGGQEYVVKEVLRIEPDRAQ-ADEVLQLREELE----ALRRQKGAREAEVLLL 704
Query: 404 ERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVT 463
++ L + ++ +E K+ E E K D E E E ++ LR ++E
Sbjct: 705 QQRVAALAEEKSRAQE---KVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEEL 761
Query: 464 T-----CKR-EKE---SENKIGIQQKLAAEL-LNKEEIIGKMQIQTRELIKNIKLNEQKV 513
+ KR EKE +E KI +++ L E E + + Q + + ++++
Sbjct: 762 SFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREK 821
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQD--LQQEIMDLKMKLLDVVHRNEELSEILA 571
+ + + L+ N + QE I D + E+ +L+++L++ + E L
Sbjct: 822 TELLRKIWALEEENAKVV-VQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLR 880
Query: 572 KKDQELEQQDKNSRGQARVIKIREELINVLKNK-ETEQSRELAALQQDLEHRMRIVDEVN 630
ELE R + ++++E V+K K + E +EL L++++ + R+++ +
Sbjct: 881 SYQSELEA----LRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCD 936
Query: 631 KQIAAKADEIQEL 643
+I EIQ L
Sbjct: 937 LEIYQLKKEIQAL 949
Score = 41.5 bits (93), Expect = 0.010
Identities = 58/294 (19%), Positives = 127/294 (43%), Gaps = 23/294 (7%)
Query: 239 IDEIRELRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQT---RNRVAKMDK 295
I +++ + + + + ++E+ ++ +T + + +E Q +Q R R A ++
Sbjct: 946 IQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERER-ASQEE 1004
Query: 296 QLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLKTGEVTTSQLIQQRDSLQA 355
Q+ E ++ + V E ++E L A A ES+ +L + LQ
Sbjct: 1005 QIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQR 1064
Query: 356 EVLECKQQIEKLTVQHKSAIQQLEEDLK--QTKRALQEQCEITKREIELKERTETELQDS 413
E ++Q+E+L + + A ++ E +++ Q + A EQ E RE + QD
Sbjct: 1065 RRTELERQLEELE-RERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDP 1123
Query: 414 RNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKREKESEN 473
+ A E + ++LE+ + L L EL+ + L E + E +
Sbjct: 1124 QQAREHALLR-LQLEEEQHRRQL-------LEGELETLRRKLAALE--------KAEVKE 1167
Query: 474 KIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVIQYEQYVRDLQAHN 527
K+ + + + E + E+ I +++ E ++ + + +V + E + +L+ HN
Sbjct: 1168 KVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHN 1221
Score = 34.3 bits (75), Expect = 1.5
Identities = 46/214 (21%), Positives = 95/214 (44%), Gaps = 13/214 (6%)
Query: 209 HERRTLIAVGEALVREVAKLRQ-DVETRNVMIDEIRELRSESENTKALEEMRHELDEERT 267
H R+ L E L R++A L + +V+ + V+ + ++ + ++E + ++ ++ L+EE
Sbjct: 1141 HRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTE--QEIQRLKSSLEEESR 1198
Query: 268 AKLAIKEKLTTTESQLRQTRNRVAKMDKQ---LREAEASITSLTGTVKMLEDQSRQKEVQ 324
+K + +++ E++L + +K K+ LRE + L LE + Q E+
Sbjct: 1199 SKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKL-QLERENLQLETRRLQSEIN 1257
Query: 325 LEA-RARKLRESLKTGEVTTS-----QLIQQRDSLQAEVLECKQQIEKLTVQHKSAIQQL 378
+ A R LR T L ++ D L+ + +I++L + S +
Sbjct: 1258 MAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKR 1317
Query: 379 EEDLKQTKRALQEQCEITKREIELKERTETELQD 412
E+ +R++ T RE+ +E L D
Sbjct: 1318 EQRENHLRRSIVVIHPDTGRELSPEEAHRAGLID 1351
>U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1
protein.
Length = 753
Score = 67.7 bits (158), Expect = 1e-10
Identities = 95/479 (19%), Positives = 220/479 (45%), Gaps = 43/479 (8%)
Query: 245 LRSESENTKALEEMRHELDEERTAKLAIKEKLTTTESQLRQTRNRVAKMDKQLREAEASI 304
+++ S+ + +EE+ ++++ + K++ ++L++ ++ D L+E E I
Sbjct: 1 VKASSKKSHQIEELEQQIEKLQAEVKGYKDE----NNRLKEKEHK--NQDDLLKEKETLI 54
Query: 305 TSLTGTVKMLEDQSRQKEVQLE--ARARKLRESLKTGEVTTSQLIQQRDS-LQAEVLECK 361
L + L++++ +VQ++ ++ L G I++ ++ L+ + +E
Sbjct: 55 QQLK---EELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERS 111
Query: 362 Q--QIEKLTVQHKSAIQQLEEDLKQTKRALQEQCEITK----REIELKE---RTETELQD 412
++E+ ++ +S I +LE +LK+ + LQ+ + TK +E++LKE + LQD
Sbjct: 112 HSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQD 171
Query: 413 SRNAI----EELQAKIIELEKSKPNPDLPTEREIDLWAELQATKETLRVTEDEVTTCKRE 468
++ + EE + E EK K + R +L A+LQ +E ++++T K++
Sbjct: 172 MKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQ 231
Query: 469 -KESENKIGI---QQKLAAELLNK---------EEIIGKMQI--QTRELIKNIKLNEQKV 513
K+ + ++ + + KL +N+ +E+ K + Q +E + N K+ E+ +
Sbjct: 232 IKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKV-EEAI 290
Query: 514 IQYEQYVRDLQAHNRTIANCQESPNGISYQDLQQEIMDLKMKLLDVVHRNEELSEILAK- 572
QYE+ +DL + I + + + ++Q+ + L+ KL +V EL + K
Sbjct: 291 QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQV-LEAKLEEVERLATELEKWKEKC 349
Query: 573 KDQELEQQDKNSRGQARVIKIREELINVLKNKETEQSRELAALQQDLEHRMRIVDEVNKQ 632
D E + ++++ + +L N+ + + + A ++ LE +M ++ + +
Sbjct: 350 NDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEA 409
Query: 633 IAAKADEIQELFATLENKQQQIHRLEKIVLALXXXXXXXXXXXXXXXXKIAALEHELAA 691
+ E+++ E +Q + +E + L +AALE +L A
Sbjct: 410 ENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKA 468
Score = 59.7 bits (138), Expect = 3e-08
Identities = 63/308 (20%), Positives = 143/308 (46%), Gaps = 22/308 (7%)
Query: 222 VREVAKLRQDVE--TRNVM-IDEIRELRSESENT--KALEEMRHELDEERTAKLAIKEKL 276
V+E+ KL++++ T N+ + + +L+ E E T + E+++ EL +K L
Sbjct: 153 VKEL-KLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADL 211
Query: 277 TTTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESL 336
E + ++ KQ+++ + ++ + K+L R K +LE + + + L
Sbjct: 212 QRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLL----RIKINELEKKKNQCSQEL 267
Query: 337 KTGEVTTSQLIQQRDSLQAE--VLECKQQIEKLTVQHKSAIQQLEEDLKQTKRALQEQCE 394
+ T QL +Q ++ + E + + ++ + L V+ K I+ + L++ ++ EQ +
Sbjct: 268 DMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEK-IIEDMRMTLEEQEQTQVEQDQ 326
Query: 395 ITKREIELKERTETELQDSRNAIEELQAKIIELEKSKPNPDLPTEREIDLWAELQATKET 454
+ + ++E ER TEL+ + +L+ K + N + E D+ +L ++
Sbjct: 327 VLEAKLEEVERLATELEKWKEKCNDLETK----NNQRSNKE--HENNTDVLGKLTNLQDE 380
Query: 455 LRVTEDEVTTCKREKESENKIGIQQKLAAELLNKEEIIGKMQIQTRELIKNIKLNEQKVI 514
L+ +E + +++ E + I Q AE + +E+ K + RE + NE +++
Sbjct: 381 LQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEM--KKYAEDRERFFK-QQNEMEIL 437
Query: 515 QYEQYVRD 522
+ +D
Sbjct: 438 TAQLTEKD 445
Score = 33.5 bits (73), Expect = 2.6
Identities = 49/233 (21%), Positives = 99/233 (42%), Gaps = 26/233 (11%)
Query: 223 REVAKLRQDVETRNVMIDEIRELRSESENTKA----LEEMRHEL-DEERTAKLAIKEKLT 277
+E ++ QD + ++E+ L +E E K LE ++ ++E + KLT
Sbjct: 317 QEQTQVEQD-QVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLT 375
Query: 278 TTESQLRQTRNRVAKMDKQLREAEASITSLTGTVKMLEDQSRQKEVQLEARARKLRESLK 337
+ +L+++ + K+ E + + + + + ++ +K + R K + +
Sbjct: 376 NLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEM- 434
Query: 338 TGEVTTSQLIQQRDSLQAEVLECKQQIEKLTVQHKSA----------IQQLEEDLKQTKR 387
E+ T+QL ++ LQ E Q + L +Q K+ I+QL+ + +T +
Sbjct: 435 --EILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSK 492
Query: 388 ALQEQCEITKREIEL----KERTE---TELQDSRNAIEELQAKIIELEKSKPN 433
+ +I + I K +TE T + SRN IE+ + E S N
Sbjct: 493 IETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTEN 545
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.311 0.127 0.330
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 74,446,370
Number of Sequences: 224733
Number of extensions: 2868431
Number of successful extensions: 38489
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 844
Number of HSP's successfully gapped in prelim test: 2364
Number of HSP's that attempted gapping in prelim test: 18650
Number of HSP's gapped (non-prelim): 11683
length of query: 698
length of database: 73,234,838
effective HSP length: 95
effective length of query: 603
effective length of database: 51,885,203
effective search space: 31286777409
effective search space used: 31286777409
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 69 (31.9 bits)
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