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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001247-TA|BGIBMGA001247-PA|IPR011072|Protein kinase
PKN/PRK1, effector, IPR009053|Prefoldin
         (490 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X65873-1|CAA46703.1|  963|Homo sapiens kinesin heavy chain protein.    60   2e-08
BC126281-1|AAI26282.1|  963|Homo sapiens kinesin family member 5...    60   2e-08
BC126279-1|AAI26280.1|  963|Homo sapiens kinesin family member 5...    60   2e-08
AL161932-2|CAH71618.1|  963|Homo sapiens kinesin family member 5...    60   2e-08
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein.                58   5e-08
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.                58   5e-08
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.                58   5e-08
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.           58   5e-08
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.           58   5e-08
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.            58   5e-08
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.            58   5e-08
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.            58   5e-08
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.            58   5e-08
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.            58   5e-08
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.            58   5e-08
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.             58   7e-08
BC078168-1|AAH78168.1|  887|Homo sapiens KIAA1212 protein protein.     58   7e-08
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.               58   7e-08
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein...    58   7e-08
AB014535-1|BAA31610.2|  864|Homo sapiens KIAA0635 protein protein.     58   9e-08
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot...    56   3e-07
AK125925-1|BAC86346.1|  623|Homo sapiens protein ( Homo sapiens ...    56   4e-07
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote...    55   7e-07
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250...    55   7e-07
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ...    55   7e-07
L06148-1|AAA35921.1|  579|Homo sapiens golgin-165 protein.             54   9e-07
D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein.                 54   9e-07
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein.       54   9e-07
AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2...    54   9e-07
AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein.           54   1e-06
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.      54   2e-06
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav...    54   2e-06
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc...    54   2e-06
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.             53   2e-06
BC048203-1|AAH48203.1|  663|Homo sapiens Unknown (protein for IM...    53   2e-06
BC014109-1|AAH14109.1|  670|Homo sapiens leucine rich repeat con...    53   2e-06
AL132765-6|CAC10587.1|  977|Homo sapiens ribosome binding protei...    53   2e-06
AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protei...    53   2e-06
BC115701-1|AAI15702.1|  828|Homo sapiens SLMAP protein protein.        52   3e-06
AY517555-1|AAT44528.1|  941|Homo sapiens hypothetical rhabdomyos...    52   3e-06
BC128578-1|AAI28579.1|  751|Homo sapiens RRBP1 protein protein.        52   6e-06
BC128577-1|AAI28578.1|  934|Homo sapiens RRBP1 protein protein.        52   6e-06
AF006751-1|AAC25977.1|  977|Homo sapiens ES/130 protein.               52   6e-06
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.     52   6e-06
AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein.     52   6e-06
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.      51   8e-06
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.      51   8e-06
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.      51   8e-06
BC000099-1|AAH00099.4|  655|Homo sapiens RRBP1 protein protein.        51   8e-06
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.     51   8e-06
AK027863-1|BAB55415.1|  612|Homo sapiens protein ( Homo sapiens ...    51   8e-06
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.           51   1e-05
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.                51   1e-05
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot...    51   1e-05
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-...    51   1e-05
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-...    51   1e-05
BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein.        51   1e-05
BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein.        51   1e-05
AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein.             51   1e-05
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-...    51   1e-05
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-...    51   1e-05
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein.             51   1e-05
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p...    51   1e-05
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein.     51   1e-05
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein.     51   1e-05
BC114627-1|AAI14628.1|  790|Homo sapiens SLMAP protein protein.        50   1e-05
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.         50   1e-05
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110...    50   1e-05
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110...    50   1e-05
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein.     50   1e-05
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein.           50   1e-05
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat...    50   1e-05
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.                 50   2e-05
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.           50   2e-05
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p...    50   2e-05
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav...    49   3e-05
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ...    49   3e-05
AB058696-1|BAB47422.1| 1270|Homo sapiens KIAA1793 protein protein.     49   4e-05
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no...    48   6e-05
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha...    48   6e-05
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle...    48   6e-05
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.                 48   6e-05
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM...    48   6e-05
BC007570-1|AAH07570.1|  649|Homo sapiens FBF1 protein protein.         48   6e-05
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy...    48   6e-05
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ...    48   1e-04
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ...    48   1e-04
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ...    48   1e-04
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ...    48   1e-04
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.                 47   1e-04
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.    47   1e-04
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,...    47   1e-04
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,...    47   1e-04
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110...    47   1e-04
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ...    47   1e-04
AF083322-1|AAC32373.1|  994|Homo sapiens centriole associated pr...    47   1e-04
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p...    47   1e-04
U93121-1|AAB88727.1|  753|Homo sapiens M-phase phosphoprotein-1 ...    47   2e-04
BC112391-1|AAI12392.1|  957|Homo sapiens ELKS/RAB6-interacting/C...    47   2e-04
BC111550-1|AAI11551.1|  957|Homo sapiens ERC2 protein protein.         47   2e-04
AY739715-1|AAW65984.1|  617|Homo sapiens M-phase phosphoprotein ...    47   2e-04
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ...    47   2e-04
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related...    47   2e-04
AB002376-1|BAA20832.2|  970|Homo sapiens KIAA0378 protein.             47   2e-04
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ...    46   2e-04
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch...    46   3e-04
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR...    46   3e-04
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ...    46   3e-04
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ...    46   3e-04
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C...    46   3e-04
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C...    46   3e-04
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein.        46   3e-04
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,...    46   3e-04
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,...    46   3e-04
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.         46   3e-04
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.           46   3e-04
AB053469-1|BAC54108.1|  720|Homo sapiens ELKS gamma protein.           46   3e-04
AB053468-1|BAC54107.1|  992|Homo sapiens ELKS beta protein.            46   3e-04
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein.     46   3e-04
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.     46   3e-04
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy...    46   4e-04
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (...    46   4e-04
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p...    46   4e-04
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p...    46   4e-04
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ...    46   4e-04
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ...    46   4e-04
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ...    46   4e-04
BC064528-1|AAH64528.1|  762|Homo sapiens coiled-coil domain cont...    46   4e-04
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi...    46   4e-04
AL451139-16|CAI15849.2|  434|Homo sapiens coiled-coil domain con...    46   4e-04
AL451139-13|CAI15848.2|  762|Homo sapiens coiled-coil domain con...    46   4e-04
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi...    46   4e-04
AL355877-3|CAH71541.2|  434|Homo sapiens coiled-coil domain cont...    46   4e-04
AL355877-2|CAH71540.2|  762|Homo sapiens coiled-coil domain cont...    46   4e-04
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi...    46   4e-04
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi...    46   4e-04
AK091682-1|BAC03719.1|  936|Homo sapiens protein ( Homo sapiens ...    46   4e-04
AK024038-1|BAB14794.1|  762|Homo sapiens protein ( Homo sapiens ...    46   4e-04
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain...    46   4e-04
AF273047-1|AAG34907.1|  623|Homo sapiens CTCL tumor antigen se20...    46   4e-04
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti...    46   4e-04
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l...    46   4e-04
X03740-1|CAA27380.1|  876|Homo sapiens protein ( Human skeletal ...    45   5e-04
BX538186-1|CAD98058.1|  971|Homo sapiens hypothetical protein pr...    45   5e-04
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.      45   5e-04
BC129821-1|AAI29822.1|  315|Homo sapiens FLJ36144 protein protein.     45   5e-04
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ...    45   5e-04
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ...    45   5e-04
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.        45   5e-04
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ...    45   5e-04
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/...    45   5e-04
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ...    45   5e-04
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.     45   5e-04
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch...    45   7e-04
BC112121-1|AAI12122.1|  478|Homo sapiens growth arrest-specific ...    45   7e-04
BC104785-1|AAI04786.1|  478|Homo sapiens growth arrest-specific ...    45   7e-04
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote...    45   7e-04
AK131384-1|BAD18535.1|  326|Homo sapiens protein ( Homo sapiens ...    45   7e-04
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.      45   7e-04
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.     45   7e-04
AF050079-1|AAC69519.1|  478|Homo sapiens growth arrest specific ...    45   7e-04
AF050078-1|AAC69518.1|  478|Homo sapiens growth arrest specific ...    45   7e-04
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein.               45   7e-04
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein.               45   7e-04
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein.                  44   0.001
BC104044-1|AAI04045.1|  830|Homo sapiens kinesin family member 7...    44   0.001
BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance ...    44   0.001
AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance ...    44   0.001
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein...    44   0.001
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein.      44   0.001
AF020043-1|AAC14893.1| 1217|Homo sapiens chromosome-associated p...    44   0.001
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein.               44   0.001
X06825-1|CAA29971.1|  284|Homo sapiens protein ( Human mRNA for ...    44   0.001
M19715-1|AAA61227.1|  229|Homo sapiens TPM1 protein.                   44   0.001
DQ679757-1|ABG74698.1| 1215|Homo sapiens intersectin 1 short for...    44   0.001
DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short for...    44   0.001
DQ679755-1|ABG74696.1| 1149|Homo sapiens intersectin 1 short for...    44   0.001
DQ679754-1|ABG74695.1| 1144|Homo sapiens intersectin 1 short for...    44   0.001
DQ386455-1|ABD72328.1| 1020|Homo sapiens intersectin 1 short for...    44   0.001
DQ340865-1|ABC69037.1| 1076|Homo sapiens intersectin 1 short for...    44   0.001
BX538175-1|CAD98050.1|  627|Homo sapiens hypothetical protein pr...    44   0.001
BX537985-1|CAD97945.1| 1202|Homo sapiens hypothetical protein pr...    44   0.001
BX537964-1|CAD97928.1|  898|Homo sapiens hypothetical protein pr...    44   0.001
BC117560-1|AAI17561.1| 1144|Homo sapiens ITSN1 protein protein.        44   0.001
BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 doma...    44   0.001
BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein.        44   0.001
BC105632-1|AAI05633.1|  898|Homo sapiens chromosome 10 open read...    44   0.001
BC103499-1|AAI03500.1|  898|Homo sapiens chromosome 10 open read...    44   0.001
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.    44   0.001
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein.        44   0.001
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige...    44   0.001
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr...    44   0.001
AL133410-4|CAI10977.1|  284|Homo sapiens tropomyosin 2 (beta) pr...    44   0.001
AK024959-1|BAB15043.1|  696|Homo sapiens protein ( Homo sapiens ...    44   0.001
AF273054-1|AAM44457.1|  613|Homo sapiens CTCL tumor antigen HD-C...    44   0.001
AF114488-1|AAD29953.1| 1220|Homo sapiens intersectin short isofo...    44   0.001
AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isofor...    44   0.001
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein.           44   0.001
AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form p...    44   0.001
AF064243-1|AAC78610.1| 1220|Homo sapiens intersectin short form ...    44   0.001
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform...    44   0.001
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform...    44   0.001
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein.     44   0.001
AB209625-1|BAD92862.1|  459|Homo sapiens dynactin 1 isoform 1 va...    44   0.001
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein.     44   0.001
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.             44   0.001
X04201-1|CAA27798.1|  285|Homo sapiens protein ( Human skeletal ...    44   0.002
BC052988-1|AAH52988.1|  980|Homo sapiens retinoic acid induced 1...    44   0.002
BC051733-1|AAH51733.1| 1026|Homo sapiens LUZP1 protein protein.        44   0.002
BC008425-1|AAH08425.1|  285|Homo sapiens tropomyosin 3 protein.        44   0.002
BC008407-1|AAH08407.1|  285|Homo sapiens tropomyosin 3 protein.        44   0.002
AY317139-1|AAP84319.1|  983|Homo sapiens RAI14 isoform protein.        44   0.002
AL590431-11|CAH71269.1|  284|Homo sapiens tropomyosin 3 protein.       44   0.002
AL031428-1|CAI19705.1| 1026|Homo sapiens leucine zipper protein ...    44   0.002
AJ132949-1|CAB36967.1|  585|Homo sapiens rfg5 protein protein.         44   0.002
AF155135-1|AAF44722.1|  980|Homo sapiens novel retinal pigment e...    44   0.002
AB037755-1|BAA92572.1|  989|Homo sapiens KIAA1334 protein protein.     44   0.002
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.          43   0.002
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak...    43   0.002
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,...    43   0.002
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,...    43   0.002
BC023566-1|AAH23566.1|  740|Homo sapiens RAS and EF-hand domain ...    43   0.002
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.               43   0.002
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he...    43   0.002
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he...    43   0.002
AL499602-1|CAH70678.1|  740|Homo sapiens RAS and EF-hand domain ...    43   0.002
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont...    43   0.002
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont...    43   0.002
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.          43   0.002
AK131080-1|BAC85130.1|  563|Homo sapiens FLJ00279 protein protein.     43   0.002
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY...    43   0.002
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.     43   0.002
BC098576-1|AAH98576.1|  918|Homo sapiens inner centromere protei...    43   0.003
BC046212-1|AAH46212.1|  364|Homo sapiens Similar to cytomatrix p...    43   0.003
BC017837-1|AAH17837.1|  311|Homo sapiens Unknown (protein for IM...    43   0.003
AY714053-1|AAU04398.1|  918|Homo sapiens inner centromere protei...    43   0.003
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit...    43   0.003
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein.         43   0.003
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot...    43   0.003
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.              43   0.003
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.     43   0.003
AB015617-1|BAA88763.1|  948|Homo sapiens ELKS protein.                 43   0.003
U90028-1|AAB94805.1|  975|Homo sapiens bicaudal-D protein.             42   0.004
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co...    42   0.004
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-...    42   0.004
BC112273-1|AAI12274.1|  830|Homo sapiens kinesin family member 7...    42   0.004
BC112271-1|AAI12272.1|  830|Homo sapiens kinesin family member 7...    42   0.004
BC073744-1|AAH73744.1|  648|Homo sapiens ITSN1 protein protein.        42   0.004
BC058925-1|AAH58925.1|  634|Homo sapiens ITSN1 protein protein.        42   0.004
AY884293-1|AAX84184.1| 1117|Homo sapiens cytospin A protein.           42   0.004
AY358384-1|AAQ88750.1|  830|Homo sapiens EQYK340 protein.              42   0.004
AK074153-1|BAB84979.1| 1046|Homo sapiens FLJ00226 protein protein.     42   0.004
AB209022-1|BAD92259.1|  939|Homo sapiens KIAA0376 protein varian...    42   0.004
AB208965-1|BAD92202.1|  705|Homo sapiens Rho-associated, coiled-...    42   0.004
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein.     42   0.004
AB002374-1|BAA21574.1|  885|Homo sapiens KIAA0376 protein.             42   0.004
X03541-1|CAA27243.1|  641|Homo sapiens protein ( Human mRNA of t...    42   0.005
U51587-1|AAB81549.1|  767|Homo sapiens Golgi complex autoantigen...    42   0.005
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.                42   0.005
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei...    42   0.005
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec...    42   0.005
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec...    42   0.005
AL590431-10|CAH71268.1|  247|Homo sapiens tropomyosin 3 protein.       42   0.005
AL590431-9|CAH71267.1|  248|Homo sapiens tropomyosin 3 protein.        42   0.005
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3...    42   0.005
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3...    42   0.005
AK025690-1|BAB15219.1|  746|Homo sapiens protein ( Homo sapiens ...    42   0.005
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub...    42   0.006
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.               42   0.006
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ...    42   0.006
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr...    42   0.006
BC080545-1|AAH80545.1|  498|Homo sapiens MYH11 protein protein.        42   0.006
BC032762-1|AAH32762.1|  571|Homo sapiens OPTN protein protein.         42   0.006
BC023021-1|AAH23021.1|  731|Homo sapiens golgi autoantigen, golg...    42   0.006
BC013876-1|AAH13876.1|  577|Homo sapiens optineurin protein.           42   0.006
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S...    42   0.006
AY644768-1|AAV85456.1|  731|Homo sapiens cell proliferation-indu...    42   0.006
AY354204-1|AAQ63889.2|  972|Homo sapiens retinoic acid induced 1...    42   0.006
AL451125-2|CAI14346.1|  767|Homo sapiens golgi autoantigen, golg...    42   0.006
AL355355-6|CAI16549.1|  577|Homo sapiens optineurin protein.           42   0.006
AL355355-5|CAI16550.1|  571|Homo sapiens optineurin protein.           42   0.006
AL354928-1|CAI39632.1|  767|Homo sapiens golgi autoantigen, golg...    42   0.006
AK126045-1|BAC86410.1|  978|Homo sapiens galactosaminyltransfera...    42   0.006
AK124447-1|BAC85854.1|  434|Homo sapiens protein ( Homo sapiens ...    42   0.006
AF420373-1|AAL76329.1|  577|Homo sapiens optineurin isoform 3 pr...    42   0.006
AF420372-1|AAL76328.1|  577|Homo sapiens optineurin isoform 2 pr...    42   0.006
AF420371-1|AAL76327.1|  577|Homo sapiens optineurin isoform 1 pr...    42   0.006
AF283527-1|AAG00497.1|  577|Homo sapiens FIP2 protein.                 42   0.006
AF085199-1|AAD09753.1|  731|Homo sapiens golgin-84 protein.            42   0.006
AF061034-2|AAC16047.1|  520|Homo sapiens FIP2 protein.                 42   0.006
AF061034-1|AAC16046.1|  577|Homo sapiens FIP2 protein.                 42   0.006
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant...    42   0.006
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant...    42   0.006
X95654-1|CAA64956.1|  976|Homo sapiens polypeptide of 976 aa pro...    41   0.009
X69292-1|CAA49154.1|  881|Homo sapiens smooth muscle mysosin  he...    41   0.009
U72849-1|AAD00186.1| 2033|Homo sapiens envoplakin protein.             41   0.009
U53786-1|AAC64662.1| 2033|Homo sapiens envoplakin protein.             41   0.009
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav...    41   0.009
BC126105-1|AAI26106.1| 2033|Homo sapiens envoplakin protein.           41   0.009
BC126103-1|AAI26104.1| 2033|Homo sapiens envoplakin protein.           41   0.009
BC103765-1|AAI03766.1|  691|Homo sapiens NUMA1 protein protein.        41   0.009
BC032853-1|AAH32853.1|  767|Homo sapiens golgi autoantigen, golg...    41   0.009
BC027493-1|AAH27493.1|  691|Homo sapiens Unknown (protein for IM...    41   0.009
BC016175-1|AAH16175.1|  279|Homo sapiens Unknown (protein for IM...    41   0.009
AL833308-1|CAD89924.1|  878|Homo sapiens hypothetical protein pr...    41   0.009
AK097336-1|BAC05002.1|  454|Homo sapiens protein ( Homo sapiens ...    41   0.009
AF020091-1|AAB69327.1|  622|Homo sapiens smooth muscle myosin he...    41   0.009
AF013570-1|AAB69326.1|  588|Homo sapiens smooth muscle myosin he...    41   0.009
Z99496-1|CAI21605.1|  805|Homo sapiens chromosome 6 open reading...    41   0.011
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige...    41   0.011
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige...    41   0.011
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein.           41   0.011
DQ444714-1|ABE01857.1|  805|Homo sapiens cenexin 1 protein.            41   0.011
DQ444713-1|ABE01856.1|  824|Homo sapiens cenexin 1 variant 1 pro...    41   0.011
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k...    41   0.011
BC118982-1|AAI18983.1|  553|Homo sapiens KIAA2012 protein protein.     41   0.011
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein.           41   0.011
BC091500-1|AAH91500.1|  829|Homo sapiens ODF2 protein protein.         41   0.011
BC047871-1|AAH47871.1|  933|Homo sapiens CDC42BPB protein protein.     41   0.011
BC010629-1|AAH10629.1|  763|Homo sapiens outer dense fiber of sp...    41   0.011
AY366499-1|AAQ73195.1|  805|Homo sapiens outer dense fiber of sp...    41   0.011
AL590005-3|CAI14988.1| 5457|Homo sapiens dystonin protein.             41   0.011
AL589993-1|CAI16048.1|  805|Homo sapiens chromosome 6 open readi...    41   0.011
AL512448-3|CAI16610.1| 5144|Homo sapiens dystonin protein.             41   0.011
AL512448-2|CAI16608.1| 5457|Homo sapiens dystonin protein.             41   0.011
AL512422-3|CAI14342.1| 5457|Homo sapiens dystonin protein.             41   0.011
AL445287-6|CAH71069.1|  805|Homo sapiens outer dense fiber of sp...    41   0.011
AL390069-1|CAI14134.1|  805|Homo sapiens chromosome 6 open readi...    41   0.011
AL359091-23|CAI13506.1|  805|Homo sapiens outer dense fiber of s...    41   0.011
AL137008-4|CAI20332.1| 5144|Homo sapiens dystonin protein.             41   0.011
AL137008-3|CAI20331.1| 5457|Homo sapiens dystonin protein.             41   0.011
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein.             41   0.011
AL096710-4|CAI22045.1| 5144|Homo sapiens dystonin protein.             41   0.011
AL096710-2|CAI22043.1| 5457|Homo sapiens dystonin protein.             41   0.011
AK097517-1|BAC05084.1|  621|Homo sapiens protein ( Homo sapiens ...    41   0.011
AF400226-1|AAL62061.1| 5171|Homo sapiens bullous pemphigoid anti...    41   0.011
AF308284-1|AAG48252.1|  546|Homo sapiens serologically defined b...    41   0.011
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k...    41   0.011
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein.           41   0.011
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein.           41   0.011
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel...    41   0.011
AB095932-1|BAC23108.1|  555|Homo sapiens KIAA2012 protein protein.     41   0.011
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.     41   0.011
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein.     41   0.011
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein.        40   0.015
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.          40   0.015
X04588-1|CAB37185.1|  248|Homo sapiens protein ( Human 2.5 kb mR...    40   0.015
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.       40   0.015
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein.               40   0.015
EF179183-1|ABN05286.1|  295|Homo sapiens troponin T type 2 (card...    40   0.015
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein.               40   0.015
BC072428-1|AAH72428.1|  248|Homo sapiens tropomyosin 3 protein.        40   0.015
BC050555-1|AAH50555.1|  873|Homo sapiens KTN1 protein protein.         40   0.015
BC015403-1|AAH15403.1|  248|Homo sapiens tropomyosin 3 protein.        40   0.015
BC002653-1|AAH02653.1|  285|Homo sapiens troponin T type 2 (card...    40   0.015
BC000771-1|AAH00771.1|  248|Homo sapiens tropomyosin 3 protein.        40   0.015
AY536375-1|AAT66048.1|  820|Homo sapiens rhabdomyosarcoma antige...    40   0.015
AY277394-1|AAP96757.1|  226|Homo sapiens troponin T cardiac isof...    40   0.015
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot...    40   0.015
AY004867-1|AAF87083.1|  247|Homo sapiens tropomyosin isoform pro...    40   0.015
AL590431-7|CAH71264.1|  248|Homo sapiens tropomyosin 3 protein.        40   0.015
AL590431-5|CAH71266.1|  248|Homo sapiens tropomyosin 3 protein.        40   0.015
AF474157-1|AAL84570.1|  247|Homo sapiens TPMsk3 protein.               40   0.015
AF039690-1|AAC18039.1|  414|Homo sapiens antigen NY-CO-8 protein.      40   0.015
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.                 40   0.020
U33822-1|AAC52059.1|  803|Homo sapiens TXBP181 protein.                40   0.020
DQ424903-1|ABD83668.1|  245|Homo sapiens tropomyosin 1 alpha var...    40   0.020
BC130564-1|AAI30565.1|  905|Homo sapiens KIAA1524 protein.             40   0.020
BC110997-1|AAI10998.1|  916|Homo sapiens coiled-coil domain cont...    40   0.020
BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil do...    40   0.020
BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil do...    40   0.020
BC066969-1|AAH66969.1|  278|Homo sapiens CCDC121 protein protein.      40   0.020
BC066936-1|AAH66936.1|  278|Homo sapiens coiled-coil domain cont...    40   0.020
BC040264-1|AAH40264.1|  751|Homo sapiens coiled-coil domain cont...    40   0.020
BC017659-1|AAH17659.1|  285|Homo sapiens KIAA1524 protein protein.     40   0.020
BC012785-1|AAH12785.1|  174|Homo sapiens ODF2 protein protein.         40   0.020
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p...    40   0.020
AL832024-1|CAD89923.1|  988|Homo sapiens hypothetical protein pr...    40   0.020
AL831815-1|CAD38529.1|  969|Homo sapiens hypothetical protein pr...    40   0.020
AL590452-8|CAH72528.1| 2240|Homo sapiens phosphodiesterase 4D in...    40   0.020
AL590452-7|CAH72527.1|  988|Homo sapiens phosphodiesterase 4D in...    40   0.020
AL590452-6|CAH72526.1|  969|Homo sapiens phosphodiesterase 4D in...    40   0.020
AL590452-4|CAH72524.1| 2346|Homo sapiens phosphodiesterase 4D in...    40   0.020
AL590452-3|CAH72523.1| 2362|Homo sapiens phosphodiesterase 4D in...    40   0.020
AL138796-7|CAI22827.1| 2240|Homo sapiens phosphodiesterase 4D in...    40   0.020
AL138796-6|CAI22826.1|  988|Homo sapiens phosphodiesterase 4D in...    40   0.020
AL138796-5|CAI22825.1|  969|Homo sapiens phosphodiesterase 4D in...    40   0.020
AL138796-4|CAI22824.1| 2346|Homo sapiens phosphodiesterase 4D in...    40   0.020
AL138796-3|CAI22823.1| 2362|Homo sapiens phosphodiesterase 4D in...    40   0.020
AK125354-1|BAC86143.1|  278|Homo sapiens protein ( Homo sapiens ...    40   0.020
AK055217-1|BAB70876.1|  688|Homo sapiens protein ( Homo sapiens ...    40   0.020
AK025336-1|BAB15114.1|  963|Homo sapiens protein ( Homo sapiens ...    40   0.020
AK022912-1|BAB14305.1|  472|Homo sapiens protein ( Homo sapiens ...    40   0.020
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do...    40   0.020
AF334474-1|AAL11632.1|  905|Homo sapiens p90 autoantigen protein.      40   0.020
AF155115-1|AAD42881.1|  472|Homo sapiens NY-REN-58 antigen protein.    40   0.020
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein.              40   0.020
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein.              40   0.020
AB040957-1|BAA96048.1|  884|Homo sapiens KIAA1524 protein protein.     40   0.020
AB032945-1|BAA86433.2| 1854|Homo sapiens KIAA1119 protein protein.     40   0.020
AB007923-1|BAA32299.2| 2296|Homo sapiens KIAA0454 protein protein.     40   0.020
X97053-1|CAA65765.1|  566|Homo sapiens plectin protein.                40   0.026
X15786-1|CAA33787.1|  899|Homo sapiens retII protein.                  40   0.026
U04824-1|AAA19586.1|  779|Homo sapiens PITSLRE alpha 2-1 protein.      40   0.026
M21984-1|AAA36777.1|  258|Homo sapiens troponin T protein.             40   0.026
DQ778624-1|ABG77458.1|  250|Homo sapiens troponin T type 3 protein.    40   0.026
CR541927-1|CAG46725.1|  256|Homo sapiens TNNT3 protein.                40   0.026
BT019997-1|AAV38800.1|  256|Homo sapiens troponin T3, skeletal, ...    40   0.026
BC127816-1|AAI27817.1|  416|Homo sapiens Unknown (protein for IM...    40   0.026
BC125087-1|AAI25088.1|  568|Homo sapiens CCDC41 protein protein.       40   0.026
BC125086-1|AAI25087.1|  634|Homo sapiens CCDC41 protein protein.       40   0.026
BC117327-1|AAI17328.1|  250|Homo sapiens troponin T type 3 (skel...    40   0.026
BC050446-1|AAH50446.1|  272|Homo sapiens TNNT3 protein protein.        40   0.026
AL590005-2|CAI14989.1| 7543|Homo sapiens dystonin protein.             40   0.026
AL512448-1|CAI16609.1| 7543|Homo sapiens dystonin protein.             40   0.026
AL512422-2|CAI14341.1| 7543|Homo sapiens dystonin protein.             40   0.026
AL137008-2|CAI20330.1| 7543|Homo sapiens dystonin protein.             40   0.026
AL133410-3|CAI10976.1|  322|Homo sapiens tropomyosin 2 (beta) pr...    40   0.026
AL133410-1|CAI10975.1|  284|Homo sapiens tropomyosin 2 (beta) pr...    40   0.026
AL096710-3|CAI22044.1| 7543|Homo sapiens dystonin protein.             40   0.026
AL031283-6|CAI21428.1|  692|Homo sapiens forkhead-associated (FH...    40   0.026
AF331638-1|AAL56068.2|  903|Homo sapiens PP1221 protein.               40   0.026
AF263742-1|AAF72196.1|  693|Homo sapiens golgin-like protein pro...    40   0.026
AF026276-1|AAF21629.1|  258|Homo sapiens fast skeletal troponin ...    40   0.026
M75165-1|AAB59509.1|  284|Homo sapiens tropomyosin protein.            39   0.035
M74817-1|AAA61230.1|  284|Homo sapiens tropomyosin-1 protein.          39   0.035
M12125-1|AAA36773.1|  284|Homo sapiens protein ( Human fibroblas...    39   0.035
BC021134-1|AAH21134.1|  903|Homo sapiens centrobin, centrosomal ...    39   0.035
BC014055-1|AAH14055.3|  805|Homo sapiens CNTROB protein protein.       39   0.035
BC011776-1|AAH11776.1|  284|Homo sapiens tropomyosin 2 (beta) pr...    39   0.035
AY160227-1|AAO22136.1|  925|Homo sapiens centrobin beta protein.       39   0.035
AY160226-1|AAO22135.1|  903|Homo sapiens centrobin alpha protein.      39   0.035
AL445287-5|CAH71068.1|  765|Homo sapiens outer dense fiber of sp...    39   0.035
AL359091-22|CAI13505.1|  765|Homo sapiens outer dense fiber of s...    39   0.035
AL133410-2|CAI10974.1|  284|Homo sapiens tropomyosin 2 (beta) pr...    39   0.035
AL133027-1|CAB61359.1| 1033|Homo sapiens hypothetical protein pr...    39   0.035
AK223258-1|BAD96978.1|  284|Homo sapiens tropomyosin 2 (beta) is...    39   0.035
AF527734-1|AAP85633.1|  439|Homo sapiens medulloblastoma antigen...    39   0.035
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei...    39   0.035
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei...    39   0.035
AF329092-1|AAN16206.1|  764|Homo sapiens GPBP-interacting protei...    39   0.035
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian...    39   0.035
BC091490-1|AAH91490.1|  620|Homo sapiens ODF2L protein protein.        39   0.046
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei...    39   0.046
AK125783-1|BAC86289.1|  731|Homo sapiens protein ( Homo sapiens ...    39   0.046
AK023385-1|BAB14554.1|  284|Homo sapiens protein ( Homo sapiens ...    39   0.046
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei...    39   0.046
AF209746-1|AAF17621.1|  257|Homo sapiens beta tropomyosin protein.     39   0.046
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg...    39   0.046
AB202104-1|BAE78628.1|  756|Homo sapiens chromosome 6 open readi...    39   0.046
X74819-1|CAA52818.1|  288|Homo sapiens cardiac troponin T protein.     38   0.060
L40162-1|AAA67422.1|  288|Homo sapiens troponin T cardiac isofor...    38   0.060
BC131515-1|AAI31516.1|  632|Homo sapiens GOLGA6 protein protein.       38   0.060
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi...    38   0.060
AL833273-1|CAD91152.1| 1509|Homo sapiens hypothetical protein pr...    38   0.060
AL590431-12|CAH71270.1|  242|Homo sapiens tropomyosin 3 protein.       38   0.060
AL139421-4|CAI22511.1|  720|Homo sapiens coiled-coil domain cont...    38   0.060
AL138742-1|CAI22698.1| 1325|Homo sapiens KIAA1009 protein.             38   0.060
AK125236-1|BAC86093.1|  232|Homo sapiens protein ( Homo sapiens ...    38   0.060
AK092690-1|BAC03946.1|  243|Homo sapiens protein ( Homo sapiens ...    38   0.060
AF266285-1|AAF72535.1|  693|Homo sapiens golgin-like protein pro...    38   0.060
AB210045-1|BAE06127.1| 1043|Homo sapiens KIF5A variant protein p...    38   0.060
AB023226-1|BAA76853.2| 1345|Homo sapiens KIAA1009 protein protein.     38   0.060
X05276-1|CAA28888.1|  248|Homo sapiens protein ( Human mRNA for ...    38   0.080
X03741-1|CAA27381.1|  635|Homo sapiens protein ( Human cardiac m...    38   0.080
U73682-1|AAB86589.1|  776|Homo sapiens meningioma-expressed anti...    38   0.080
M21665-1|AAA36345.1|  524|Homo sapiens protein ( Human beta-myos...    38   0.080
M21664-1|AAA36344.1|  532|Homo sapiens protein ( Human alpha-myo...    38   0.080
M19714-1|AAA61226.1|  264|Homo sapiens TPM1 protein.                   38   0.080
L16782-1|AAC37542.1|  566|Homo sapiens putative M phase phosphop...    38   0.080
BX640689-1|CAE45814.1|  256|Homo sapiens hypothetical protein pr...    38   0.080
BX538286-1|CAD98081.1|  724|Homo sapiens hypothetical protein pr...    38   0.080
BX537708-1|CAD97819.1| 1605|Homo sapiens hypothetical protein pr...    38   0.080
BT019634-1|AAV38440.1|  248|Homo sapiens tropomyosin 4 protein.        38   0.080
BC067225-1|AAH67225.1|  248|Homo sapiens tropomyosin 4 protein.        38   0.080
BC062543-1|AAH62543.1|  653|Homo sapiens CLIP1 protein protein.        38   0.080
BC060803-1|AAH60803.1|  715|Homo sapiens chromosome 6 open readi...    38   0.080
BC050434-1|AAH50434.1|  273|Homo sapiens FLJ10154 protein protein.     38   0.080
BC037576-1|AAH37576.1|  248|Homo sapiens tropomyosin 4 protein.        38   0.080
BC036124-1|AAH36124.1|  424|Homo sapiens MIPOL1 protein protein.       38   0.080
BC019283-1|AAH19283.1|  469|Homo sapiens TRAF interacting protei...    38   0.080
BC002827-1|AAH02827.1|  248|Homo sapiens tropomyosin 4 protein.        38   0.080
BC000310-1|AAH00310.1|  469|Homo sapiens TRAF interacting protei...    38   0.080
AL442127-3|CAI13168.1|  273|Homo sapiens RP11-297I6.1 protein.         38   0.080
AK098740-1|BAC05400.1|  293|Homo sapiens protein ( Homo sapiens ...    38   0.080
AK056673-1|BAB71249.1|  883|Homo sapiens protein ( Homo sapiens ...    38   0.080
AK026958-1|BAB15602.1|  715|Homo sapiens protein ( Homo sapiens ...    38   0.080
AK001016-1|BAA91467.1|  273|Homo sapiens protein ( Homo sapiens ...    38   0.080
AF310722-1|AAK17926.1|  320|Homo sapiens tropomyosin 4-anaplasti...    38   0.080
AF250731-1|AAO27830.1|  713|Homo sapiens centrosomal colon cance...    38   0.080
AF186109-1|AAG17014.1|  237|Homo sapiens TPM4-ALK fusion oncopro...    38   0.080
AB209992-1|BAE06074.1| 2319|Homo sapiens DSP variant protein pro...    38   0.080
AB067524-1|BAB67830.1|  704|Homo sapiens KIAA1937 protein protein.     38   0.080
X13939-1|CAA32122.1|  328|Homo sapiens laminin B2 protein.             38   0.11 
U06698-1|AAA20231.1| 1032|Homo sapiens neuronal kinesin heavy ch...    38   0.11 
M83216-1|AAA58419.1|  793|Homo sapiens caldesmon protein.              38   0.11 
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein.       38   0.11 
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein.                  38   0.11 
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.             38   0.11 
BC060826-1|AAH60826.1|  843|Homo sapiens GOLGA3 protein protein.       38   0.11 

>X65873-1|CAA46703.1|  963|Homo sapiens kinesin heavy chain protein.
          Length = 963

 Score = 59.7 bits (138), Expect = 2e-08
 Identities = 73/375 (19%), Positives = 154/375 (41%), Gaps = 16/375 (4%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVD 109
           + D+  E +++  + + E LK ++    E+      D+D M  ++ RLQ EN   + +V 
Sbjct: 431 QLDDKDEEINQQ-SQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVK 489

Query: 110 ETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
           E  +       N +     V+  +  Y++L++EL+++ A   ++   +   + M    + 
Sbjct: 490 EVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKK 549

Query: 165 RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
           R A +   L    AE  IA   + D++Q      I+      ++   + ++E    V + 
Sbjct: 550 RAAEMMASLLKDLAEIGIA-VGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRC 608

Query: 225 RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR 284
           +  E   +TE    K+ E EK  A                   LQ+   +  +L +    
Sbjct: 609 KQLE-STQTE-SNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDA 666

Query: 285 RCLEYVPCKENEPT-DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
              E V  +  E   + E E   ++Q         E++++  R      ++SL    + +
Sbjct: 667 LSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAK 726

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
                  K+ T+L D+ QK++  Q+ +  + E  K+ +Q  ++  ++L  ++   ++ R 
Sbjct: 727 A------KLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQ 780

Query: 404 YDCYSKDVSYPELQT 418
                ++    ELQT
Sbjct: 781 DLKGLEETVAKELQT 795



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 29/148 (19%), Positives = 72/148 (48%), Gaps = 4/148 (2%)

Query: 280 DMERRRCLEYVPCKENEPTDRETEIWKELQMT---RGALLRSEEELRQSRAEKDSFLNSL 336
           D ERR+C E +     +  D++ EI ++ Q+    +  +L  EE L  +R ++D+    L
Sbjct: 415 DAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAEL 474

Query: 337 SRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
           +R+ A+ + ++    ++   L +      +  Q ++++ +  + +   + Q    LA++ 
Sbjct: 475 NRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASID 534

Query: 396 LEVKRLRNYDCYSKDVSYPELQTEILDL 423
            E+++L+    + K  +   + + + DL
Sbjct: 535 AELQKLKEMTNHQKKRAAEMMASLLKDL 562


>BC126281-1|AAI26282.1|  963|Homo sapiens kinesin family member 5B
           protein.
          Length = 963

 Score = 59.7 bits (138), Expect = 2e-08
 Identities = 73/375 (19%), Positives = 154/375 (41%), Gaps = 16/375 (4%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVD 109
           + D+  E +++  + + E LK ++    E+      D+D M  ++ RLQ EN   + +V 
Sbjct: 431 QLDDKDEEINQQ-SQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVK 489

Query: 110 ETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
           E  +       N +     V+  +  Y++L++EL+++ A   ++   +   + M    + 
Sbjct: 490 EVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKK 549

Query: 165 RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
           R A +   L    AE  IA   + D++Q      I+      ++   + ++E    V + 
Sbjct: 550 RAAEMMASLLKDLAEIGIA-VGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRC 608

Query: 225 RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR 284
           +  E   +TE    K+ E EK  A                   LQ+   +  +L +    
Sbjct: 609 KQLE-STQTE-SNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDA 666

Query: 285 RCLEYVPCKENEPT-DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
              E V  +  E   + E E   ++Q         E++++  R      ++SL    + +
Sbjct: 667 LSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAK 726

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
                  K+ T+L D+ QK++  Q+ +  + E  K+ +Q  ++  ++L  ++   ++ R 
Sbjct: 727 A------KLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQ 780

Query: 404 YDCYSKDVSYPELQT 418
                ++    ELQT
Sbjct: 781 DLKGLEETVAKELQT 795



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 29/148 (19%), Positives = 72/148 (48%), Gaps = 4/148 (2%)

Query: 280 DMERRRCLEYVPCKENEPTDRETEIWKELQMT---RGALLRSEEELRQSRAEKDSFLNSL 336
           D ERR+C E +     +  D++ EI ++ Q+    +  +L  EE L  +R ++D+    L
Sbjct: 415 DAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAEL 474

Query: 337 SRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
           +R+ A+ + ++    ++   L +      +  Q ++++ +  + +   + Q    LA++ 
Sbjct: 475 NRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASID 534

Query: 396 LEVKRLRNYDCYSKDVSYPELQTEILDL 423
            E+++L+    + K  +   + + + DL
Sbjct: 535 AELQKLKEMTNHQKKRAAEMMASLLKDL 562


>BC126279-1|AAI26280.1|  963|Homo sapiens kinesin family member 5B
           protein.
          Length = 963

 Score = 59.7 bits (138), Expect = 2e-08
 Identities = 73/375 (19%), Positives = 154/375 (41%), Gaps = 16/375 (4%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVD 109
           + D+  E +++  + + E LK ++    E+      D+D M  ++ RLQ EN   + +V 
Sbjct: 431 QLDDKDEEINQQ-SQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVK 489

Query: 110 ETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
           E  +       N +     V+  +  Y++L++EL+++ A   ++   +   + M    + 
Sbjct: 490 EVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKK 549

Query: 165 RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
           R A +   L    AE  IA   + D++Q      I+      ++   + ++E    V + 
Sbjct: 550 RAAEMMASLLKDLAEIGIA-VGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRC 608

Query: 225 RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR 284
           +  E   +TE    K+ E EK  A                   LQ+   +  +L +    
Sbjct: 609 KQLE-STQTE-SNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDA 666

Query: 285 RCLEYVPCKENEPT-DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
              E V  +  E   + E E   ++Q         E++++  R      ++SL    + +
Sbjct: 667 LSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAK 726

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
                  K+ T+L D+ QK++  Q+ +  + E  K+ +Q  ++  ++L  ++   ++ R 
Sbjct: 727 A------KLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQ 780

Query: 404 YDCYSKDVSYPELQT 418
                ++    ELQT
Sbjct: 781 DLKGLEETVAKELQT 795



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 29/148 (19%), Positives = 72/148 (48%), Gaps = 4/148 (2%)

Query: 280 DMERRRCLEYVPCKENEPTDRETEIWKELQMT---RGALLRSEEELRQSRAEKDSFLNSL 336
           D ERR+C E +     +  D++ EI ++ Q+    +  +L  EE L  +R ++D+    L
Sbjct: 415 DAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAEL 474

Query: 337 SRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
           +R+ A+ + ++    ++   L +      +  Q ++++ +  + +   + Q    LA++ 
Sbjct: 475 NRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASID 534

Query: 396 LEVKRLRNYDCYSKDVSYPELQTEILDL 423
            E+++L+    + K  +   + + + DL
Sbjct: 535 AELQKLKEMTNHQKKRAAEMMASLLKDL 562


>AL161932-2|CAH71618.1|  963|Homo sapiens kinesin family member 5B
           protein.
          Length = 963

 Score = 59.7 bits (138), Expect = 2e-08
 Identities = 73/375 (19%), Positives = 154/375 (41%), Gaps = 16/375 (4%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVD 109
           + D+  E +++  + + E LK ++    E+      D+D M  ++ RLQ EN   + +V 
Sbjct: 431 QLDDKDEEINQQ-SQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVK 489

Query: 110 ETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
           E  +       N +     V+  +  Y++L++EL+++ A   ++   +   + M    + 
Sbjct: 490 EVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKK 549

Query: 165 RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
           R A +   L    AE  IA   + D++Q      I+      ++   + ++E    V + 
Sbjct: 550 RAAEMMASLLKDLAEIGIA-VGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRC 608

Query: 225 RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR 284
           +  E   +TE    K+ E EK  A                   LQ+   +  +L +    
Sbjct: 609 KQLE-STQTE-SNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDA 666

Query: 285 RCLEYVPCKENEPT-DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
              E V  +  E   + E E   ++Q         E++++  R      ++SL    + +
Sbjct: 667 LSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAK 726

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
                  K+ T+L D+ QK++  Q+ +  + E  K+ +Q  ++  ++L  ++   ++ R 
Sbjct: 727 A------KLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQ 780

Query: 404 YDCYSKDVSYPELQT 418
                ++    ELQT
Sbjct: 781 DLKGLEETVAKELQT 795



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 29/148 (19%), Positives = 72/148 (48%), Gaps = 4/148 (2%)

Query: 280 DMERRRCLEYVPCKENEPTDRETEIWKELQMT---RGALLRSEEELRQSRAEKDSFLNSL 336
           D ERR+C E +     +  D++ EI ++ Q+    +  +L  EE L  +R ++D+    L
Sbjct: 415 DAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAEL 474

Query: 337 SRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
           +R+ A+ + ++    ++   L +      +  Q ++++ +  + +   + Q    LA++ 
Sbjct: 475 NRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASID 534

Query: 396 LEVKRLRNYDCYSKDVSYPELQTEILDL 423
            E+++L+    + K  +   + + + DL
Sbjct: 535 AELQKLKEMTNHQKKRAAEMMASLLKDL 562


>Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein.
          Length = 4684

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2289 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2348

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2349 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2407

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2408 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2463

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2464 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2523

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2524 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2583

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2584 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2642

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2643 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2695

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2696 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2751

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2752 VTASQVAATKTLPNGRDALDGPAAE 2776



 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 105/504 (20%), Positives = 204/504 (40%), Gaps = 35/504 (6%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1447 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1506

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1507 EKQRQLAEAHAQAKAQAEREAKELQQRIQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1566

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1567 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1626

Query: 174  KDTKAEFEIAKKKHKDLEQLVNRLAIE-RSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
            +  + E E  +++ +D  Q   +  +E  S    + +  RE+    + + + R+  ++A 
Sbjct: 1627 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1686

Query: 233  TEFLQAKV--AEQ-----EKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDM--- 281
                QA+V  A Q     E ++  A                QL+ S ++  + +  +   
Sbjct: 1687 RWLCQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1746

Query: 282  -ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLR--SEEELRQ---SRAEKDSFLNS 335
             ERR   +    +  E  +R+ E W +L+      LR  +EE L+Q   ++AE +     
Sbjct: 1747 AERRAQQQAEAERAREEAERQLERW-QLKANEALRLRLQAEEVLQQKSLAQAEAEKQKEE 1805

Query: 336  LSRIAQGEGTESFQDKMATELLDRE-QKIVKLQQTIDEQR---ENEKSMEQTMT-QYENQ 390
              R A+  G    Q     EL ++E +K  +L +   +QR   E E    +  T Q E Q
Sbjct: 1806 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1865

Query: 391  LAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRALMLE 449
               L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++     +
Sbjct: 1866 RQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKAKAEEESRSTSEKSKQ 1924

Query: 450  RHERAADLFARMVRARKDLAALLD 473
            R E  A  F  +      L AL +
Sbjct: 1925 RLEAEAGRFRELAEEAARLRALAE 1948



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 74/373 (19%), Positives = 142/373 (38%), Gaps = 22/373 (5%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1829 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1888

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1889 ELEAELAKVRAEMEVLLASKAKAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1947

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1948 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 2002

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 2003 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 2059

Query: 328  EKDSFL---NSLSRIAQGEGTESFQ-DKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
             ++  L    S  + A G+     +  ++ +   D  +   + +     QR+     E+ 
Sbjct: 2060 VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERR 2119

Query: 384  MTQYENQL-AALRLEVKRLRNYDCYSKDVSYPELQT-EILDLHLQVETLSRERTALITAA 441
              + E ++  +L  E +  R      ++V   + +  E   L  + E  S  +  L   A
Sbjct: 2120 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEA 2179

Query: 442  ASRALMLERHERA 454
            A + L  E    A
Sbjct: 2180 AQKRLQAEEKAHA 2192



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 58/277 (20%), Positives = 111/277 (40%), Gaps = 16/277 (5%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
            ++ +E  A +A  E  A+ ++ L +   RI +       +K + E+   + + L     R
Sbjct: 2059 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2118

Query: 197  LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQA--KVAEQEKSKAVAXXXX 254
               E      K     E+A    + A   V   KA+ E  ++  + AEQE ++ +     
Sbjct: 2119 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQE 2178

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWKE--LQMT 311
                           + + +   L   +++ + +      E E   R  E  +E  +Q  
Sbjct: 2179 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDRLRGEAEAARRAAEEAEEARVQAE 2238

Query: 312  RGAL-----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            R A      +   E L+QS AE+ +   + ++ A  E      ++ A      EQ  ++ 
Sbjct: 2239 REAAQSRRQVEEAERLKQS-AEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQAALRQ 2296

Query: 367  QQTID-EQRENEKSMEQTM---TQYENQLAALRLEVK 399
            +Q  D E  +++K  EQT+    Q E +L  LRL+++
Sbjct: 2297 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2333


>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
          Length = 4574

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2179 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2238

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2239 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2297

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2298 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2353

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2354 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2413

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2414 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2473

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2474 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2532

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2533 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2585

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2586 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2641

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2642 VTASQVAATKTLPNGRDALDGPAAE 2666



 Score = 52.0 bits (119), Expect = 5e-06
 Identities = 105/507 (20%), Positives = 203/507 (40%), Gaps = 41/507 (8%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1337 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1396

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1397 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1456

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1457 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1516

Query: 174  KDTKAEFEIAKKKHKDLEQ--------LVNRL------AIERSHATVKVKELREQAETAE 219
            +  + E E  +++ +D  Q        L +R+      A E+  A   ++ELR QAE AE
Sbjct: 1517 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEELRLQAEEAE 1576

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
            +  + R +E +   +   A    Q  ++A                   LQ       +L 
Sbjct: 1577 R--RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1634

Query: 280  DMERRRCLEYVPC-KENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDS 331
            +   RR  +     +  E  +RE E W +L+      LR + E       L Q+ AEK  
Sbjct: 1635 EEAERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1693

Query: 332  FLNSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQY 387
                     +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q 
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQG 1752

Query: 388  ENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRAL 446
            E Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++   
Sbjct: 1753 EQQRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1811

Query: 447  MLERHERAADLFARMVRARKDLAALLD 473
              +R E  A  F  +      L AL +
Sbjct: 1812 SKQRLEAEAGRFRELAEEAARLRALAE 1838



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 51/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2064 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2123

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + A  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2124 RVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2182

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2183 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2242

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2243 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2301

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2302 QVAEE 2306



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1719 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1778

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1779 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1837

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1838 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 1892

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 1893 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 1949

Query: 328  EKDSFL 333
             ++  L
Sbjct: 1950 VEEEIL 1955



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 71/369 (19%), Positives = 146/369 (39%), Gaps = 36/369 (9%)

Query: 134  LNEELSKERAAREA-LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ 192
            + E L++ R A ++ L+      E  LR  R     +E ++   KA FE A     +LE 
Sbjct: 1918 IEERLAQLRKASDSELERQKGLVEDTLRQRRQ----VEEEILALKASFEKAAAGKAELEL 1973

Query: 193  LVNRLAIE-----RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFL---------QA 238
             + R+        RS    +++  R++   AE+  + R +E++ +             +A
Sbjct: 1974 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2033

Query: 239  KVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENE-- 296
             + E E+ KA                  QLQ  ++ + + +  E +     V  KE E  
Sbjct: 2034 ALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ 2093

Query: 297  -PTDRETEIWKELQMTRGALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMAT 354
                +E  +  +L+    A  R+ EE  ++R + +     +  ++ + E  +   ++ A 
Sbjct: 2094 QTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAEEQAQ 2153

Query: 355  ELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP 414
                 +    KL++  +++       EQ   + +    A   + K+        K     
Sbjct: 2154 ARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK----A 2209

Query: 415  ELQTEILDLHLQVETLSRERTAL------ITAAASRALMLERHERAADLFARMVRARKDL 468
            +++ E+  L LQ+E    ++  L      + A A+ A   +R +   +LF+  VR + + 
Sbjct: 2210 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR-QRSQVEEELFS--VRVQMEE 2266

Query: 469  AALLDGRID 477
             + L  RI+
Sbjct: 2267 LSKLKARIE 2275


>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
          Length = 4574

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2179 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2238

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2239 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2297

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2298 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2353

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2354 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2413

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2414 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2473

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2474 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2532

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2533 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2585

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2586 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2641

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2642 VTASQVAATKTLPNGRDALDGPAAE 2666



 Score = 52.0 bits (119), Expect = 5e-06
 Identities = 105/507 (20%), Positives = 203/507 (40%), Gaps = 41/507 (8%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1337 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1396

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1397 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1456

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1457 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1516

Query: 174  KDTKAEFEIAKKKHKDLEQ--------LVNRL------AIERSHATVKVKELREQAETAE 219
            +  + E E  +++ +D  Q        L +R+      A E+  A   ++ELR QAE AE
Sbjct: 1517 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEELRLQAEEAE 1576

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
            +  + R +E +   +   A    Q  ++A                   LQ       +L 
Sbjct: 1577 R--RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLR 1634

Query: 280  DMERRRCLEYVPC-KENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDS 331
            +   RR  +     +  E  +RE E W +L+      LR + E       L Q+ AEK  
Sbjct: 1635 EEAERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1693

Query: 332  FLNSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQY 387
                     +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q 
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQG 1752

Query: 388  ENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRAL 446
            E Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++   
Sbjct: 1753 EQQRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEK 1811

Query: 447  MLERHERAADLFARMVRARKDLAALLD 473
              +R E  A  F  +      L AL +
Sbjct: 1812 SKQRLEAEAGRFRELAEEAARLRALAE 1838



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 51/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2064 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2123

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + A  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2124 RVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2182

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2183 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2242

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2243 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2301

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2302 QVAEE 2306



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1719 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1778

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1779 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1837

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1838 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 1892

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 1893 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 1949

Query: 328  EKDSFL 333
             ++  L
Sbjct: 1950 VEEEIL 1955



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 71/369 (19%), Positives = 146/369 (39%), Gaps = 36/369 (9%)

Query: 134  LNEELSKERAAREA-LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ 192
            + E L++ R A ++ L+      E  LR  R     +E ++   KA FE A     +LE 
Sbjct: 1918 IEERLAQLRKASDSELERQKGLVEDTLRQRRQ----VEEEILALKASFEKAAAGKAELEL 1973

Query: 193  LVNRLAIE-----RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFL---------QA 238
             + R+        RS    +++  R++   AE+  + R +E++ +             +A
Sbjct: 1974 ELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA 2033

Query: 239  KVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENE-- 296
             + E E+ KA                  QLQ  ++ + + +  E +     V  KE E  
Sbjct: 2034 ALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ 2093

Query: 297  -PTDRETEIWKELQMTRGALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMAT 354
                +E  +  +L+    A  R+ EE  ++R + +     +  ++ + E  +   ++ A 
Sbjct: 2094 QTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAEEQAQ 2153

Query: 355  ELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP 414
                 +    KL++  +++       EQ   + +    A   + K+        K     
Sbjct: 2154 ARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK----A 2209

Query: 415  ELQTEILDLHLQVETLSRERTAL------ITAAASRALMLERHERAADLFARMVRARKDL 468
            +++ E+  L LQ+E    ++  L      + A A+ A   +R +   +LF+  VR + + 
Sbjct: 2210 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAAR-QRSQVEEELFS--VRVQMEE 2266

Query: 469  AALLDGRID 477
             + L  RI+
Sbjct: 2267 LSKLKARIE 2275


>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
          Length = 4547

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2212 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2270

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2271 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2326

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2327 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2386

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2387 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2446

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2447 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2506 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2558

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2614

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2615 VTASQVAATKTLPNGRDALDGPAAE 2639



 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 101/505 (20%), Positives = 205/505 (40%), Gaps = 37/505 (7%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1310 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1369

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1370 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1429

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1430 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489

Query: 174  KDTKAEFEIAKKKHKDLEQLVNRLAIE-RSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
            +  + E E  +++ +D  Q   +  +E  S    + +  RE+    + + + R+  ++A 
Sbjct: 1490 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1549

Query: 233  TEFLQAKV--AEQ-----EKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDM--- 281
                QA+V  A Q     E ++  A                QL+ S ++  + +  +   
Sbjct: 1550 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1609

Query: 282  -ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDSFL 333
             ERR   +    +  E  +RE E W +L+      LR + E       L Q+ AEK    
Sbjct: 1610 AERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1668

Query: 334  NSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQYEN 389
                   +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q E 
Sbjct: 1669 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQGEQ 1727

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRALML 448
            Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++     
Sbjct: 1728 QRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1786

Query: 449  ERHERAADLFARMVRARKDLAALLD 473
            +R E  A  F  +      L AL +
Sbjct: 1787 QRLEAEAGRFRELAEEAARLRALAE 1811



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1692 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1751

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1752 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1810

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1811 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 1865

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 1866 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 1922

Query: 328  EKDSFL 333
             ++  L
Sbjct: 1923 VEEEIL 1928



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2037 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2096

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + +  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2097 RVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2155

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2156 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2215

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2216 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2274

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2275 QVAEE 2279



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 58/277 (20%), Positives = 110/277 (39%), Gaps = 16/277 (5%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
            ++ +E  A +A  E  A+ ++ L +   RI +       +K + E+   + + L     R
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1981

Query: 197  LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXX 254
               E      K     E+A    + A   V   KA+ E  +   + AEQE ++ +     
Sbjct: 1982 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2041

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWKE--LQMT 311
                           + + +   L   +++ + +      E E   R  E  +E  +Q  
Sbjct: 2042 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2101

Query: 312  RGAL-----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            R A      +   E L+QS AE+ +   + ++ A  E      ++ A      EQ  ++ 
Sbjct: 2102 REAAQSRRQVEEAERLKQS-AEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQAALRQ 2159

Query: 367  QQTID-EQRENEKSMEQTM---TQYENQLAALRLEVK 399
            +Q  D E  +++K  EQT+    Q E +L  LRL+++
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2196


>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
          Length = 4551

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2156 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2215

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2216 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2274

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2275 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2330

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2331 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2390

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2391 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2450

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2451 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2509

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2510 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2562

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2563 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2618

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2619 VTASQVAATKTLPNGRDALDGPAAE 2643



 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 101/505 (20%), Positives = 205/505 (40%), Gaps = 37/505 (7%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1314 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1373

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1374 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1433

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1434 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1493

Query: 174  KDTKAEFEIAKKKHKDLEQLVNRLAIE-RSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
            +  + E E  +++ +D  Q   +  +E  S    + +  RE+    + + + R+  ++A 
Sbjct: 1494 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1553

Query: 233  TEFLQAKV--AEQ-----EKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDM--- 281
                QA+V  A Q     E ++  A                QL+ S ++  + +  +   
Sbjct: 1554 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1613

Query: 282  -ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDSFL 333
             ERR   +    +  E  +RE E W +L+      LR + E       L Q+ AEK    
Sbjct: 1614 AERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1672

Query: 334  NSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQYEN 389
                   +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q E 
Sbjct: 1673 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQGEQ 1731

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRALML 448
            Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++     
Sbjct: 1732 QRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1790

Query: 449  ERHERAADLFARMVRARKDLAALLD 473
            +R E  A  F  +      L AL +
Sbjct: 1791 QRLEAEAGRFRELAEEAARLRALAE 1815



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1696 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1755

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1756 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1814

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1815 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 1869

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 1870 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 1926

Query: 328  EKDSFL 333
             ++  L
Sbjct: 1927 VEEEIL 1932



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2041 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2100

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + +  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2101 RVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2159

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2160 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2219

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2220 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2278

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2279 QVAEE 2283



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 58/277 (20%), Positives = 110/277 (39%), Gaps = 16/277 (5%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
            ++ +E  A +A  E  A+ ++ L +   RI +       +K + E+   + + L     R
Sbjct: 1926 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1985

Query: 197  LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXX 254
               E      K     E+A    + A   V   KA+ E  +   + AEQE ++ +     
Sbjct: 1986 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2045

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWKE--LQMT 311
                           + + +   L   +++ + +      E E   R  E  +E  +Q  
Sbjct: 2046 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2105

Query: 312  RGAL-----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            R A      +   E L+QS AE+ +   + ++ A  E      ++ A      EQ  ++ 
Sbjct: 2106 REAAQSRRQVEEAERLKQS-AEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQAALRQ 2163

Query: 367  QQTID-EQRENEKSMEQTM---TQYENQLAALRLEVK 399
            +Q  D E  +++K  EQT+    Q E +L  LRL+++
Sbjct: 2164 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2200


>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
          Length = 4547

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2212 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2270

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2271 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2326

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2327 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2386

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2387 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2446

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2447 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2506 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2558

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2559 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2614

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2615 VTASQVAATKTLPNGRDALDGPAAE 2639



 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 101/505 (20%), Positives = 205/505 (40%), Gaps = 37/505 (7%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1310 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1369

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1370 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1429

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1430 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489

Query: 174  KDTKAEFEIAKKKHKDLEQLVNRLAIE-RSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
            +  + E E  +++ +D  Q   +  +E  S    + +  RE+    + + + R+  ++A 
Sbjct: 1490 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1549

Query: 233  TEFLQAKV--AEQ-----EKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDM--- 281
                QA+V  A Q     E ++  A                QL+ S ++  + +  +   
Sbjct: 1550 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1609

Query: 282  -ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDSFL 333
             ERR   +    +  E  +RE E W +L+      LR + E       L Q+ AEK    
Sbjct: 1610 AERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1668

Query: 334  NSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQYEN 389
                   +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q E 
Sbjct: 1669 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQGEQ 1727

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRALML 448
            Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++     
Sbjct: 1728 QRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1786

Query: 449  ERHERAADLFARMVRARKDLAALLD 473
            +R E  A  F  +      L AL +
Sbjct: 1787 QRLEAEAGRFRELAEEAARLRALAE 1811



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1692 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1751

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1752 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1810

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1811 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 1865

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 1866 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 1922

Query: 328  EKDSFL 333
             ++  L
Sbjct: 1923 VEEEIL 1928



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2037 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2096

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + +  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2097 RVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2155

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2156 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2215

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2216 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2274

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2275 QVAEE 2279



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 58/277 (20%), Positives = 110/277 (39%), Gaps = 16/277 (5%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
            ++ +E  A +A  E  A+ ++ L +   RI +       +K + E+   + + L     R
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1981

Query: 197  LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXX 254
               E      K     E+A    + A   V   KA+ E  +   + AEQE ++ +     
Sbjct: 1982 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2041

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWKE--LQMT 311
                           + + +   L   +++ + +      E E   R  E  +E  +Q  
Sbjct: 2042 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2101

Query: 312  RGAL-----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            R A      +   E L+QS AE+ +   + ++ A  E      ++ A      EQ  ++ 
Sbjct: 2102 REAAQSRRQVEEAERLKQS-AEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQAALRQ 2159

Query: 367  QQTID-EQRENEKSMEQTM---TQYENQLAALRLEVK 399
            +Q  D E  +++K  EQT+    Q E +L  LRL+++
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2196


>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
          Length = 4515

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2120 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2179

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2180 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2238

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2239 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2294

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2295 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2354

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2355 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2414

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2415 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2473

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2474 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2526

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2527 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2582

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2583 VTASQVAATKTLPNGRDALDGPAAE 2607



 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 101/505 (20%), Positives = 205/505 (40%), Gaps = 37/505 (7%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1278 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1337

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1338 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1397

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1398 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1457

Query: 174  KDTKAEFEIAKKKHKDLEQLVNRLAIE-RSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
            +  + E E  +++ +D  Q   +  +E  S    + +  RE+    + + + R+  ++A 
Sbjct: 1458 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1517

Query: 233  TEFLQAKV--AEQ-----EKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDM--- 281
                QA+V  A Q     E ++  A                QL+ S ++  + +  +   
Sbjct: 1518 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1577

Query: 282  -ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDSFL 333
             ERR   +    +  E  +RE E W +L+      LR + E       L Q+ AEK    
Sbjct: 1578 AERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1636

Query: 334  NSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQYEN 389
                   +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q E 
Sbjct: 1637 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQGEQ 1695

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRALML 448
            Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++     
Sbjct: 1696 QRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1754

Query: 449  ERHERAADLFARMVRARKDLAALLD 473
            +R E  A  F  +      L AL +
Sbjct: 1755 QRLEAEAGRFRELAEEAARLRALAE 1779



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1660 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1719

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1720 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1778

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1779 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 1833

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 1834 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 1890

Query: 328  EKDSFL 333
             ++  L
Sbjct: 1891 VEEEIL 1896



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2005 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2064

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + +  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2065 RVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2123

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2124 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2183

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2184 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2242

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2243 QVAEE 2247



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 58/277 (20%), Positives = 110/277 (39%), Gaps = 16/277 (5%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
            ++ +E  A +A  E  A+ ++ L +   RI +       +K + E+   + + L     R
Sbjct: 1890 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1949

Query: 197  LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXX 254
               E      K     E+A    + A   V   KA+ E  +   + AEQE ++ +     
Sbjct: 1950 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2009

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWKE--LQMT 311
                           + + +   L   +++ + +      E E   R  E  +E  +Q  
Sbjct: 2010 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2069

Query: 312  RGAL-----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            R A      +   E L+QS AE+ +   + ++ A  E      ++ A      EQ  ++ 
Sbjct: 2070 REAAQSRRQVEEAERLKQS-AEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQAALRQ 2127

Query: 367  QQTID-EQRENEKSMEQTM---TQYENQLAALRLEVK 399
            +Q  D E  +++K  EQT+    Q E +L  LRL+++
Sbjct: 2128 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2164


>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
          Length = 4684

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2289 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2348

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2349 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2407

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2408 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2463

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2464 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2523

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2524 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2583

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2584 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2642

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2643 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2695

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2696 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2751

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2752 VTASQVAATKTLPNGRDALDGPAAE 2776



 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 101/505 (20%), Positives = 205/505 (40%), Gaps = 37/505 (7%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1447 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1506

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1507 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1566

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1567 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1626

Query: 174  KDTKAEFEIAKKKHKDLEQLVNRLAIE-RSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
            +  + E E  +++ +D  Q   +  +E  S    + +  RE+    + + + R+  ++A 
Sbjct: 1627 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1686

Query: 233  TEFLQAKV--AEQ-----EKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDM--- 281
                QA+V  A Q     E ++  A                QL+ S ++  + +  +   
Sbjct: 1687 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1746

Query: 282  -ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDSFL 333
             ERR   +    +  E  +RE E W +L+      LR + E       L Q+ AEK    
Sbjct: 1747 AERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1805

Query: 334  NSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQYEN 389
                   +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q E 
Sbjct: 1806 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQGEQ 1864

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRALML 448
            Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++     
Sbjct: 1865 QRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1923

Query: 449  ERHERAADLFARMVRARKDLAALLD 473
            +R E  A  F  +      L AL +
Sbjct: 1924 QRLEAEAGRFRELAEEAARLRALAE 1948



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1829 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1888

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1889 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1947

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1948 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 2002

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 2003 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 2059

Query: 328  EKDSFL 333
             ++  L
Sbjct: 2060 VEEEIL 2065



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2174 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2233

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + +  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2234 RVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2292

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2293 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2352

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2353 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2411

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2412 QVAEE 2416



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 58/277 (20%), Positives = 110/277 (39%), Gaps = 16/277 (5%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
            ++ +E  A +A  E  A+ ++ L +   RI +       +K + E+   + + L     R
Sbjct: 2059 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2118

Query: 197  LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXX 254
               E      K     E+A    + A   V   KA+ E  +   + AEQE ++ +     
Sbjct: 2119 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2178

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWKE--LQMT 311
                           + + +   L   +++ + +      E E   R  E  +E  +Q  
Sbjct: 2179 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2238

Query: 312  RGAL-----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            R A      +   E L+QS AE+ +   + ++ A  E      ++ A      EQ  ++ 
Sbjct: 2239 REAAQSRRQVEEAERLKQS-AEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQAALRQ 2296

Query: 367  QQTID-EQRENEKSMEQTM---TQYENQLAALRLEVK 399
            +Q  D E  +++K  EQT+    Q E +L  LRL+++
Sbjct: 2297 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2333


>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
          Length = 4525

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2130 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2189

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2190 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2248

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2249 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2304

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2305 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2364

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2365 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2424

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2425 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2483

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2484 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2536

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2537 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2592

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2593 VTASQVAATKTLPNGRDALDGPAAE 2617



 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 101/505 (20%), Positives = 205/505 (40%), Gaps = 37/505 (7%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1288 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1347

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1348 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1407

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1408 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1467

Query: 174  KDTKAEFEIAKKKHKDLEQLVNRLAIE-RSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
            +  + E E  +++ +D  Q   +  +E  S    + +  RE+    + + + R+  ++A 
Sbjct: 1468 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1527

Query: 233  TEFLQAKV--AEQ-----EKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDM--- 281
                QA+V  A Q     E ++  A                QL+ S ++  + +  +   
Sbjct: 1528 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1587

Query: 282  -ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDSFL 333
             ERR   +    +  E  +RE E W +L+      LR + E       L Q+ AEK    
Sbjct: 1588 AERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1646

Query: 334  NSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQYEN 389
                   +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q E 
Sbjct: 1647 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQGEQ 1705

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRALML 448
            Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++     
Sbjct: 1706 QRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1764

Query: 449  ERHERAADLFARMVRARKDLAALLD 473
            +R E  A  F  +      L AL +
Sbjct: 1765 QRLEAEAGRFRELAEEAARLRALAE 1789



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1670 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1729

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1730 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1788

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1789 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 1843

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 1844 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 1900

Query: 328  EKDSFL 333
             ++  L
Sbjct: 1901 VEEEIL 1906



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2015 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2074

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + +  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2075 RVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2133

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2134 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2193

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2194 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2252

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2253 QVAEE 2257



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 58/277 (20%), Positives = 110/277 (39%), Gaps = 16/277 (5%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
            ++ +E  A +A  E  A+ ++ L +   RI +       +K + E+   + + L     R
Sbjct: 1900 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1959

Query: 197  LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXX 254
               E      K     E+A    + A   V   KA+ E  +   + AEQE ++ +     
Sbjct: 1960 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2019

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWKE--LQMT 311
                           + + +   L   +++ + +      E E   R  E  +E  +Q  
Sbjct: 2020 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2079

Query: 312  RGAL-----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            R A      +   E L+QS AE+ +   + ++ A  E      ++ A      EQ  ++ 
Sbjct: 2080 REAAQSRRQVEEAERLKQS-AEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQAALRQ 2137

Query: 367  QQTID-EQRENEKSMEQTM---TQYENQLAALRLEVK 399
            +Q  D E  +++K  EQT+    Q E +L  LRL+++
Sbjct: 2138 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2174


>AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.
          Length = 4533

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2138 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2197

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2198 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2256

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2257 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2312

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2313 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2372

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2373 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2432

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2433 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2491

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2492 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2544

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2545 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2600

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2601 VTASQVAATKTLPNGRDALDGPAAE 2625



 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 101/505 (20%), Positives = 205/505 (40%), Gaps = 37/505 (7%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1296 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1355

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1356 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1415

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1416 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1475

Query: 174  KDTKAEFEIAKKKHKDLEQLVNRLAIE-RSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
            +  + E E  +++ +D  Q   +  +E  S    + +  RE+    + + + R+  ++A 
Sbjct: 1476 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1535

Query: 233  TEFLQAKV--AEQ-----EKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDM--- 281
                QA+V  A Q     E ++  A                QL+ S ++  + +  +   
Sbjct: 1536 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1595

Query: 282  -ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDSFL 333
             ERR   +    +  E  +RE E W +L+      LR + E       L Q+ AEK    
Sbjct: 1596 AERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1654

Query: 334  NSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQYEN 389
                   +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q E 
Sbjct: 1655 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQGEQ 1713

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRALML 448
            Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++     
Sbjct: 1714 QRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1772

Query: 449  ERHERAADLFARMVRARKDLAALLD 473
            +R E  A  F  +      L AL +
Sbjct: 1773 QRLEAEAGRFRELAEEAARLRALAE 1797



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1678 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1737

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1738 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1796

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1797 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 1851

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 1852 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 1908

Query: 328  EKDSFL 333
             ++  L
Sbjct: 1909 VEEEIL 1914



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2023 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2082

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + +  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2083 RVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2141

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2142 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2201

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2202 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2260

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2261 QVAEE 2265



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 58/277 (20%), Positives = 110/277 (39%), Gaps = 16/277 (5%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
            ++ +E  A +A  E  A+ ++ L +   RI +       +K + E+   + + L     R
Sbjct: 1908 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 1967

Query: 197  LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXX 254
               E      K     E+A    + A   V   KA+ E  +   + AEQE ++ +     
Sbjct: 1968 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2027

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWKE--LQMT 311
                           + + +   L   +++ + +      E E   R  E  +E  +Q  
Sbjct: 2028 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2087

Query: 312  RGAL-----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            R A      +   E L+QS AE+ +   + ++ A  E      ++ A      EQ  ++ 
Sbjct: 2088 REAAQSRRQVEEAERLKQS-AEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQAALRQ 2145

Query: 367  QQTID-EQRENEKSMEQTM---TQYENQLAALRLEVK 399
            +Q  D E  +++K  EQT+    Q E +L  LRL+++
Sbjct: 2146 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2182


>AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.
          Length = 4574

 Score = 58.4 bits (135), Expect = 5e-08
 Identities = 115/505 (22%), Positives = 202/505 (40%), Gaps = 46/505 (9%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV----RVLSNLEWKTRNTEFDNDT--ERLHR 60
            A+Q +L +  A   +ME     A +TL +     + L+ L  +   T+   +   E L R
Sbjct: 2179 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2238

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS--ILQHKVDETSKKENEE 118
            + A   E  + +     E+  +  +  + + K   R++ EN   IL+ K +     + E 
Sbjct: 2239 LKAEATEAARQRSQVEEELFSVR-VQMEELSKLKARIEAENRALILRDKDNTQRFLQEEA 2297

Query: 119  PPCHPVQSGSYNYQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTK 177
                 V   +    V  +E ++ R  A E L +  A AE ML+     +    R     K
Sbjct: 2298 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR----LK 2353

Query: 178  AEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ 237
            AE E+ +++ +  ++   RL  ++     ++ E  +  +   +  + R  E  A  E L+
Sbjct: 2354 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLK 2413

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR---DRSIRLV----------DMERR 284
             +VAE  +++A A                +L          + LV          D +  
Sbjct: 2414 LRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAE 2473

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGAL--LRSEEELRQSRAEKDSFLNSLSRIAQG 342
            R  E +   E E    + E  K LQ+    +  ++ E+ L++++A + SFL+    + Q 
Sbjct: 2474 RLREAIAELEREKEKLQQEA-KLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2532

Query: 343  EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
            E     Q+K   E L +++ + K QQ  +EQ+  ++ MEQ     E Q     +E  R R
Sbjct: 2533 ERFIE-QEKAKLEQLFQDE-VAKAQQLREEQQRQQQQMEQ-----ERQRLVASMEEARRR 2585

Query: 403  NYDC-YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM 461
             ++          ELQ        Q E L+ E   L      +  +LE   RAA   +  
Sbjct: 2586 QHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRL----REQLQLLEEQHRAALAHSEE 2641

Query: 462  VRARKDLA--ALLDGR--IDPPPFE 482
            V A +  A   L +GR  +D P  E
Sbjct: 2642 VTASQVAATKTLPNGRDALDGPAAE 2666



 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 101/505 (20%), Positives = 205/505 (40%), Gaps = 37/505 (7%)

Query: 3    KNLIAQQNSLLEHYAILRDMESR-AGVAAETLGEVRVLSNLEWKTRNTEFDN--DTERLH 59
            +++I +   L  HY+ L  + S+     +ETL  +     L  + R  E +   + E   
Sbjct: 1337 ESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAAL 1396

Query: 60   RMVAGIAE-NLKAKINFSLEIAKIPWLDRDTMIKKIERL---QKENSILQHKVDETSKKE 115
                 +AE + +AK     E  ++    ++ ++++ E     Q++   +Q ++ +  +  
Sbjct: 1397 EKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1456

Query: 116  NEE--PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
              E        ++   +   + EE+   R   EA +     AE  L+  RAR    E Q 
Sbjct: 1457 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1516

Query: 174  KDTKAEFEIAKKKHKDLEQLVNRLAIE-RSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
            +  + E E  +++ +D  Q   +  +E  S    + +  RE+    + + + R+  ++A 
Sbjct: 1517 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1576

Query: 233  TEFLQAKV--AEQ-----EKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDM--- 281
                QA+V  A Q     E ++  A                QL+ S ++  + +  +   
Sbjct: 1577 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREE 1636

Query: 282  -ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-------LRQSRAEKDSFL 333
             ERR   +    +  E  +RE E W +L+      LR + E       L Q+ AEK    
Sbjct: 1637 AERRAQQQAEAERAREEAERELERW-QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEE 1695

Query: 334  NSLSRIAQGEGTESF--QDKMATELLDREQKIVK--LQQTIDEQRENEKSMEQTMTQYEN 389
                   +G+  E    Q ++A + L++++++ +   QQ +  ++E  +   +T  Q E 
Sbjct: 1696 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET-EQGEQ 1754

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVET-LSRERTALITAAASRALML 448
            Q   L  E+ RL+  +  +      EL+ E+  +  ++E  L+ +  A   + ++     
Sbjct: 1755 QRQLLEEELARLQR-EAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSK 1813

Query: 449  ERHERAADLFARMVRARKDLAALLD 473
            +R E  A  F  +      L AL +
Sbjct: 1814 QRLEAEAGRFRELAEEAARLRALAE 1838



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 16/246 (6%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVA 153
            + L+K+  + +    +    E E        + G    Q+L EEL++ +    A  +   
Sbjct: 1719 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1778

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSHATVKVKELR 212
              E+ L   RA +  L       + E     +K K  LE    R   E +    +++ L 
Sbjct: 1779 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFR-ELAEEAARLRALA 1837

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            E+A+   Q+A+   + Q+A  E + A     EK  A+                 + ++ R
Sbjct: 1838 EEAKRQRQLAEEDAARQRAEAERVLA-----EKLAAIGEATRLKTEAEIALKEKEAENER 1892

Query: 273  DRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWK----ELQMTRGALLRSEEELRQSRA 327
             R +   +  +RRR  E     + +  +R  ++ K    EL+  +G +   E+ LRQ R 
Sbjct: 1893 LRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV---EDTLRQRRQ 1949

Query: 328  EKDSFL 333
             ++  L
Sbjct: 1950 VEEEIL 1955



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 11/245 (4%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQ---LKDTKAEFEIAKKKHKDLEQL 193
            +L++E A +    E  A A ++ +  +    TL+++   L   + E E A++  ++ E+ 
Sbjct: 2064 QLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA 2123

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +   E + +  +V+E     ++AE+ AQ+R   Q A  E L+ +  ++   +A A   
Sbjct: 2124 RVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQA 2182

Query: 254  XXXXXXXXXXXXXQLQSFRDRSIR---LVDMERRRCLEYVPCKENEPTDRETEIWK-ELQ 309
                         + + F ++++R    V+ E       +   +++    + E+ + + +
Sbjct: 2183 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2242

Query: 310  MTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             T  A  RS  EEEL   R + +      +RI         +DK  T+   +E+   K++
Sbjct: 2243 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEE-AEKMK 2301

Query: 368  QTIDE 372
            Q  +E
Sbjct: 2302 QVAEE 2306



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 58/277 (20%), Positives = 110/277 (39%), Gaps = 16/277 (5%)

Query: 137  ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
            ++ +E  A +A  E  A+ ++ L +   RI +       +K + E+   + + L     R
Sbjct: 1949 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2008

Query: 197  LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXX 254
               E      K     E+A    + A   V   KA+ E  +   + AEQE ++ +     
Sbjct: 2009 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE 2068

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIWKE--LQMT 311
                           + + +   L   +++ + +      E E   R  E  +E  +Q  
Sbjct: 2069 AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAE 2128

Query: 312  RGAL-----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            R A      +   E L+QS AE+ +   + ++ A  E      ++ A      EQ  ++ 
Sbjct: 2129 REAAQSRRQVEEAERLKQS-AEEQAQARAQAQ-AAAEKLRKEAEQEAARRAQAEQAALRQ 2186

Query: 367  QQTID-EQRENEKSMEQTM---TQYENQLAALRLEVK 399
            +Q  D E  +++K  EQT+    Q E +L  LRL+++
Sbjct: 2187 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE 2223


>BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.
          Length = 1843

 Score = 58.0 bits (134), Expect = 7e-08
 Identities = 90/383 (23%), Positives = 163/383 (42%), Gaps = 44/383 (11%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +   + KK+E L  EN I+Q K    + +   +             + L E   ++    
Sbjct: 499 ENQRLSKKVEIL--ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
           E   E +    S LR  R++I+  E ++KD + E +I  +  K+    ++++  E+    
Sbjct: 557 EQENEHLNQTVSSLR-QRSQISA-EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK 614

Query: 206 VKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA------------EQEKSKAVAXXX 253
            +++  +E+ E AE++ ++ +   +   E LQ K+             EQE S+      
Sbjct: 615 KELEHYKEKGERAEEL-ENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENR 673

Query: 254 XXXXXXXXXXXXX-QLQSFRDRSIRLVD--MERRRCLEYVPCK---------ENEPTDRE 301
                         QL+S    + +L +  +E RR +E + C          EN+  + E
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733

Query: 302 TE-IWKELQMTRGALLRSEE--------ELRQSRAEKDSFLNSLSRIAQGEGTESFQD-K 351
            E + K L++ + +  ++E         ++   R +K +  NS  +I Q E     QD +
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK-TLENSNKKIQQLES--ELQDLE 790

Query: 352 MATELLDREQKIVKLQQTIDEQRENE-KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           M  + L +  + +K+     EQ E E KS+EQ  +Q E     L  E KRLR      KD
Sbjct: 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ-QAEIKD 849

Query: 411 VSYPELQTEILDLHLQVETLSRE 433
            +  E   +I +L  + +TLS+E
Sbjct: 850 TTLEENNVKIGNLEKENKTLSKE 872



 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 85/430 (19%), Positives = 184/430 (42%), Gaps = 31/430 (7%)

Query: 55   TERLHRMVAGI-AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE--- 110
            TERL     G+  EN + +        KI  L+ +     ++ L+ EN  LQ  ++E   
Sbjct: 751  TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESE-----LQDLEMENQTLQKNLEELKI 805

Query: 111  TSKK-ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATL 169
            +SK+ E  E     ++  +   +   ++L KE    + L++     ++ L     +I  L
Sbjct: 806  SSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN---KRLRQQAEIKDTTLEENNVKIGNL 862

Query: 170  ERQLKDTKAEFEIAKKKHKDLEQLV--NRLAIERSHATVK-VKELREQAETAEQVAQSRV 226
            E++ K    E  I K+    L++L   N+  ++R+   +K +  LRE   + +   Q   
Sbjct: 863  EKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMN 922

Query: 227  SEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRC 286
            ++ +  T  L+     +E+   +                 +L+S   +S+ + + E+   
Sbjct: 923  NDLEKLTHELEKIGLNKER---LLHDEQSTDDSRYKLLESKLESTLKKSLEIKE-EKIAA 978

Query: 287  LEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE 346
            LE    +  E T+   ++ +EL+  +    ++ E L+Q + E+    +S     +    E
Sbjct: 979  LE---ARLEESTNYNQQLRQELKTVK----KNYEALKQRQDEERMVQSSPPISGEDNKWE 1031

Query: 347  SFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDC 406
                +   ELL  + +++++++     +  +++++  + Q E Q   L+ ++  L+    
Sbjct: 1032 RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQR-QT 1090

Query: 407  YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARK 466
             S       LQT+   L ++  TL+ + T+L+   A   +     E   +    +++ R+
Sbjct: 1091 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE---SVIKERE 1147

Query: 467  DLAALLDGRI 476
            DL +L D  I
Sbjct: 1148 DLKSLYDSLI 1157



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 70/382 (18%), Positives = 144/382 (37%), Gaps = 32/382 (8%)

Query: 31  ETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENL------KAKINFSLEIAKIPW 84
           +T+  +R  S +  + R  + + + + LH  +   +  L      K +I   LE  K   
Sbjct: 565 QTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 624

Query: 85  LDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
              + +  ++  L+KEN +LQ K+       N +  C  +++       L  E  K +  
Sbjct: 625 ERAEELENELHHLEKENELLQKKI------TNLKITCEKIEALEQENSELERENRKLKKT 678

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            ++ K +    ES L    +++     +L+      + A  K   L+     L  E+   
Sbjct: 679 LDSFKNLTFQLES-LEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
              ++ L+   +  E++  S         + LQ  +    K                   
Sbjct: 738 KKGLELLKASFKKTERLEVS-YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTL 796

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
              L+  +  S RL  +E          KEN+  ++ET    +L+  +  L +  + LRQ
Sbjct: 797 QKNLEELKISSKRLEQLE----------KENKSLEQET---SQLEKDKKQLEKENKRLRQ 843

Query: 325 SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME--- 381
               KD+ L   + +  G   E     ++ E+   ++  V+L++   E +E  K      
Sbjct: 844 QAEIKDTTLEE-NNVKIG-NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDI 901

Query: 382 QTMTQYENQLAALRLEVKRLRN 403
           +T+      L + +L+ +++ N
Sbjct: 902 KTLVTLREDLVSEKLKTQQMNN 923



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 66/381 (17%), Positives = 158/381 (41%), Gaps = 21/381 (5%)

Query: 85  LDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           ++RD   KKIE L +EN  L     E ++K++ +   H         +      + +++ 
Sbjct: 396 MERDMDRKKIEELMEENMTL-----EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSL 450

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
              + E+ +S    L +    +     +L+ T    E    K   +E+   RL+ +    
Sbjct: 451 GHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 510

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
             ++ + ++  +  + +++  + E+    + ++      E+   +               
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL 570

Query: 265 XXQLQSFRDRSIRLVDMERR---RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEE- 320
             + Q   +  ++ ++ E +     ++    K ++    + +I KEL+  +    R+EE 
Sbjct: 571 RQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEEL 630

Query: 321 --ELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENE 377
             EL     E +     ++ +    E  E+ + + +   L+RE +  KL++T+D  +   
Sbjct: 631 ENELHHLEKENELLQKKITNLKITCEKIEALEQENSE--LERENR--KLKKTLDSFKNLT 686

Query: 378 KSMEQTMTQYENQLAALRLEVKR-LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTA 436
             +E ++ +  +QL    LE++R + +  C S  ++  +LQ E  +L  + E L ++   
Sbjct: 687 FQLE-SLEKENSQLDEENLELRRNVESLKCASMKMA--QLQLENKELESEKEQL-KKGLE 742

Query: 437 LITAAASRALMLERHERAADL 457
           L+ A+  +   LE   +  D+
Sbjct: 743 LLKASFKKTERLEVSYQGLDI 763


>BC078168-1|AAH78168.1|  887|Homo sapiens KIAA1212 protein protein.
          Length = 887

 Score = 58.0 bits (134), Expect = 7e-08
 Identities = 90/383 (23%), Positives = 163/383 (42%), Gaps = 44/383 (11%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +   + KK+E L  EN I+Q K    + +   +             + L E   ++    
Sbjct: 496 ENQRLSKKVEIL--ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 553

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
           E   E +    S LR  R++I+  E ++KD + E +I  +  K+    ++++  E+    
Sbjct: 554 EQENEHLNQTVSSLR-QRSQISA-EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK 611

Query: 206 VKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA------------EQEKSKAVAXXX 253
            +++  +E+ E AE++ ++ +   +   E LQ K+             EQE S+      
Sbjct: 612 KELEHYKEKGERAEEL-ENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENR 670

Query: 254 XXXXXXXXXXXXX-QLQSFRDRSIRLVD--MERRRCLEYVPCK---------ENEPTDRE 301
                         QL+S    + +L +  +E RR +E + C          EN+  + E
Sbjct: 671 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 730

Query: 302 TE-IWKELQMTRGALLRSEE--------ELRQSRAEKDSFLNSLSRIAQGEGTESFQD-K 351
            E + K L++ + +  ++E         ++   R +K +  NS  +I Q E     QD +
Sbjct: 731 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK-TLENSNKKIQQLES--ELQDLE 787

Query: 352 MATELLDREQKIVKLQQTIDEQRENE-KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           M  + L +  + +K+     EQ E E KS+EQ  +Q E     L  E KRLR      KD
Sbjct: 788 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ-QAEIKD 846

Query: 411 VSYPELQTEILDLHLQVETLSRE 433
            +  E   +I +L  + +TLS+E
Sbjct: 847 TTLEENNVKIGNLEKENKTLSKE 869



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 66/381 (17%), Positives = 158/381 (41%), Gaps = 21/381 (5%)

Query: 85  LDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           ++RD   KKIE L +EN  L     E ++K++ +   H         +      + +++ 
Sbjct: 393 MERDMDRKKIEELMEENMTL-----EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSL 447

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
              + E+ +S    L +    +     +L+ T    E    K   +E+   RL+ +    
Sbjct: 448 GHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 507

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
             ++ + ++  +  + +++  + E+    + ++      E+   +               
Sbjct: 508 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL 567

Query: 265 XXQLQSFRDRSIRLVDMERR---RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEE- 320
             + Q   +  ++ ++ E +     ++    K ++    + +I KEL+  +    R+EE 
Sbjct: 568 RQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEEL 627

Query: 321 --ELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENE 377
             EL     E +     ++ +    E  E+ + + +   L+RE +  KL++T+D  +   
Sbjct: 628 ENELHHLEKENELLQKKITNLKITCEKIEALEQENSE--LERENR--KLKKTLDSFKNLT 683

Query: 378 KSMEQTMTQYENQLAALRLEVKR-LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTA 436
             +E ++ +  +QL    LE++R + +  C S  ++  +LQ E  +L  + E L ++   
Sbjct: 684 FQLE-SLEKENSQLDEENLELRRNVESLKCASMKMA--QLQLENKELESEKEQL-KKGLE 739

Query: 437 LITAAASRALMLERHERAADL 457
           L+ A+  +   LE   +  D+
Sbjct: 740 LLKASFKKTERLEVSYQGLDI 760



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 49/222 (22%), Positives = 91/222 (40%), Gaps = 25/222 (11%)

Query: 31  ETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENL------KAKINFSLEIAKIPW 84
           +T+  +R  S +  + R  + + + + LH  +   +  L      K +I   LE  K   
Sbjct: 562 QTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 621

Query: 85  LDRDTMIKKIERLQKENSILQHKV--------------DETSKKENEEPPCHPVQSGSYN 130
              + +  ++  L+KEN +LQ K+               E S+ E E            N
Sbjct: 622 ERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKN 681

Query: 131 YQVLNEELSKERA-AREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD 189
                E L KE +   E   E+  + ES L+ A  ++A L+ + K+ ++E E  KK  + 
Sbjct: 682 LTFQLESLEKENSQLDEENLELRRNVES-LKCASMKMAQLQLENKELESEKEQLKKGLEL 740

Query: 190 LE---QLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE 228
           L+   +   RL +      ++ + L++  E + +  Q   SE
Sbjct: 741 LKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESE 782


>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
          Length = 1870

 Score = 58.0 bits (134), Expect = 7e-08
 Identities = 90/383 (23%), Positives = 163/383 (42%), Gaps = 44/383 (11%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +   + KK+E L  EN I+Q K    + +   +             + L E   ++    
Sbjct: 499 ENQRLSKKVEIL--ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
           E   E +    S LR  R++I+  E ++KD + E +I  +  K+    ++++  E+    
Sbjct: 557 EQENEHLNQTVSSLR-QRSQISA-EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK 614

Query: 206 VKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA------------EQEKSKAVAXXX 253
            +++  +E+ E AE++ ++ +   +   E LQ K+             EQE S+      
Sbjct: 615 KELEHYKEKGERAEEL-ENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENR 673

Query: 254 XXXXXXXXXXXXX-QLQSFRDRSIRLVD--MERRRCLEYVPCK---------ENEPTDRE 301
                         QL+S    + +L +  +E RR +E + C          EN+  + E
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733

Query: 302 TE-IWKELQMTRGALLRSEE--------ELRQSRAEKDSFLNSLSRIAQGEGTESFQD-K 351
            E + K L++ + +  ++E         ++   R +K +  NS  +I Q E     QD +
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK-TLENSNKKIQQLES--ELQDLE 790

Query: 352 MATELLDREQKIVKLQQTIDEQRENE-KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           M  + L +  + +K+     EQ E E KS+EQ  +Q E     L  E KRLR      KD
Sbjct: 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ-QAEIKD 849

Query: 411 VSYPELQTEILDLHLQVETLSRE 433
            +  E   +I +L  + +TLS+E
Sbjct: 850 TTLEENNVKIGNLEKENKTLSKE 872



 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 86/430 (20%), Positives = 179/430 (41%), Gaps = 32/430 (7%)

Query: 55   TERLHRMVAGI-AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE--- 110
            TERL     G+  EN + +        KI  L+ +     ++ L+ EN  LQ  ++E   
Sbjct: 751  TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESE-----LQDLEMENQTLQKNLEELKI 805

Query: 111  TSKK-ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATL 169
            +SK+ E  E     ++  +   +   ++L KE    + L++     ++ L     +I  L
Sbjct: 806  SSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN---KRLRQQAEIKDTTLEENNVKIGNL 862

Query: 170  ERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQ 229
            E++ K    E  I K+    L++L          AT+ +K L       E +   ++  Q
Sbjct: 863  EKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTL---VTLREDLVSEKLKTQ 919

Query: 230  KARTEFLQAKVAEQEK---SKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRC 286
            +   + L+    E EK   +K                   +L+S   +S+ + + E+   
Sbjct: 920  QMNND-LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKE-EKIAA 977

Query: 287  LEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE 346
            LE    +  E T+   ++ +EL+  +    ++ E L+Q + E+    +S     +    E
Sbjct: 978  LE---ARLEESTNYNQQLRQELKTVK----KNYEALKQRQDEERMVQSSPPISGEDNKWE 1030

Query: 347  SFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDC 406
                +   ELL  + +++++++     +  +++++  + Q E Q   L+ ++  L+    
Sbjct: 1031 RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQR-QT 1089

Query: 407  YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARK 466
             S       LQT+   L ++  TL+ + T+L+   A   +     E   +    +++ R+
Sbjct: 1090 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE---SVIKERE 1146

Query: 467  DLAALLDGRI 476
            DL +L D  I
Sbjct: 1147 DLKSLYDSLI 1156



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 70/382 (18%), Positives = 144/382 (37%), Gaps = 32/382 (8%)

Query: 31  ETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENL------KAKINFSLEIAKIPW 84
           +T+  +R  S +  + R  + + + + LH  +   +  L      K +I   LE  K   
Sbjct: 565 QTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 624

Query: 85  LDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
              + +  ++  L+KEN +LQ K+       N +  C  +++       L  E  K +  
Sbjct: 625 ERAEELENELHHLEKENELLQKKI------TNLKITCEKIEALEQENSELERENRKLKKT 678

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            ++ K +    ES L    +++     +L+      + A  K   L+     L  E+   
Sbjct: 679 LDSFKNLTFQLES-LEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
              ++ L+   +  E++  S         + LQ  +    K                   
Sbjct: 738 KKGLELLKASFKKTERLEVS-YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTL 796

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
              L+  +  S RL  +E          KEN+  ++ET    +L+  +  L +  + LRQ
Sbjct: 797 QKNLEELKISSKRLEQLE----------KENKSLEQET---SQLEKDKKQLEKENKRLRQ 843

Query: 325 SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME--- 381
               KD+ L   + +  G   E     ++ E+   ++  V+L++   E +E  K      
Sbjct: 844 QAEIKDTTLEE-NNVKIG-NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDI 901

Query: 382 QTMTQYENQLAALRLEVKRLRN 403
           +T+      L + +L+ +++ N
Sbjct: 902 KTLVTLREDLVSEKLKTQQMNN 923



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 66/381 (17%), Positives = 158/381 (41%), Gaps = 21/381 (5%)

Query: 85  LDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           ++RD   KKIE L +EN  L     E ++K++ +   H         +      + +++ 
Sbjct: 396 MERDMDRKKIEELMEENMTL-----EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSL 450

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
              + E+ +S    L +    +     +L+ T    E    K   +E+   RL+ +    
Sbjct: 451 GHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 510

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
             ++ + ++  +  + +++  + E+    + ++      E+   +               
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL 570

Query: 265 XXQLQSFRDRSIRLVDMERR---RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEE- 320
             + Q   +  ++ ++ E +     ++    K ++    + +I KEL+  +    R+EE 
Sbjct: 571 RQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEEL 630

Query: 321 --ELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENE 377
             EL     E +     ++ +    E  E+ + + +   L+RE +  KL++T+D  +   
Sbjct: 631 ENELHHLEKENELLQKKITNLKITCEKIEALEQENSE--LERENR--KLKKTLDSFKNLT 686

Query: 378 KSMEQTMTQYENQLAALRLEVKR-LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTA 436
             +E ++ +  +QL    LE++R + +  C S  ++  +LQ E  +L  + E L ++   
Sbjct: 687 FQLE-SLEKENSQLDEENLELRRNVESLKCASMKMA--QLQLENKELESEKEQL-KKGLE 742

Query: 437 LITAAASRALMLERHERAADL 457
           L+ A+  +   LE   +  D+
Sbjct: 743 LLKASFKKTERLEVSYQGLDI 763


>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
           protein.
          Length = 1843

 Score = 58.0 bits (134), Expect = 7e-08
 Identities = 90/383 (23%), Positives = 163/383 (42%), Gaps = 44/383 (11%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +   + KK+E L  EN I+Q K    + +   +             + L E   ++    
Sbjct: 499 ENQRLSKKVEIL--ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
           E   E +    S LR  R++I+  E ++KD + E +I  +  K+    ++++  E+    
Sbjct: 557 EQENEHLNQTVSSLR-QRSQISA-EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK 614

Query: 206 VKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA------------EQEKSKAVAXXX 253
            +++  +E+ E AE++ ++ +   +   E LQ K+             EQE S+      
Sbjct: 615 KELEHYKEKGERAEEL-ENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENR 673

Query: 254 XXXXXXXXXXXXX-QLQSFRDRSIRLVD--MERRRCLEYVPCK---------ENEPTDRE 301
                         QL+S    + +L +  +E RR +E + C          EN+  + E
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733

Query: 302 TE-IWKELQMTRGALLRSEE--------ELRQSRAEKDSFLNSLSRIAQGEGTESFQD-K 351
            E + K L++ + +  ++E         ++   R +K +  NS  +I Q E     QD +
Sbjct: 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK-TLENSNKKIQQLES--ELQDLE 790

Query: 352 MATELLDREQKIVKLQQTIDEQRENE-KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           M  + L +  + +K+     EQ E E KS+EQ  +Q E     L  E KRLR      KD
Sbjct: 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ-QAEIKD 849

Query: 411 VSYPELQTEILDLHLQVETLSRE 433
            +  E   +I +L  + +TLS+E
Sbjct: 850 TTLEENNVKIGNLEKENKTLSKE 872



 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 85/430 (19%), Positives = 184/430 (42%), Gaps = 31/430 (7%)

Query: 55   TERLHRMVAGI-AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE--- 110
            TERL     G+  EN + +        KI  L+ +     ++ L+ EN  LQ  ++E   
Sbjct: 751  TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESE-----LQDLEMENQTLQKNLEELKI 805

Query: 111  TSKK-ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATL 169
            +SK+ E  E     ++  +   +   ++L KE    + L++     ++ L     +I  L
Sbjct: 806  SSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN---KRLRQQAEIKDTTLEENNVKIGNL 862

Query: 170  ERQLKDTKAEFEIAKKKHKDLEQLV--NRLAIERSHATVK-VKELREQAETAEQVAQSRV 226
            E++ K    E  I K+    L++L   N+  ++R+   +K +  LRE   + +   Q   
Sbjct: 863  EKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMN 922

Query: 227  SEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRC 286
            ++ +  T  L+     +E+   +                 +L+S   +S+ + + E+   
Sbjct: 923  NDLEKLTHELEKIGLNKER---LLHDEQSTDDSRYKLLESKLESTLKKSLEIKE-EKIAA 978

Query: 287  LEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE 346
            LE    +  E T+   ++ +EL+  +    ++ E L+Q + E+    +S     +    E
Sbjct: 979  LE---ARLEESTNYNQQLRQELKTVK----KNYEALKQRQDEERMVQSSPPISGEDNKWE 1031

Query: 347  SFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDC 406
                +   ELL  + +++++++     +  +++++  + Q E Q   L+ ++  L+    
Sbjct: 1032 RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQR-QT 1090

Query: 407  YSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARK 466
             S       LQT+   L ++  TL+ + T+L+   A   +     E   +    +++ R+
Sbjct: 1091 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE---SVIKERE 1147

Query: 467  DLAALLDGRI 476
            DL +L D  I
Sbjct: 1148 DLKSLYDSLI 1157



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 70/382 (18%), Positives = 144/382 (37%), Gaps = 32/382 (8%)

Query: 31  ETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENL------KAKINFSLEIAKIPW 84
           +T+  +R  S +  + R  + + + + LH  +   +  L      K +I   LE  K   
Sbjct: 565 QTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG 624

Query: 85  LDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
              + +  ++  L+KEN +LQ K+       N +  C  +++       L  E  K +  
Sbjct: 625 ERAEELENELHHLEKENELLQKKI------TNLKITCEKIEALEQENSELERENRKLKKT 678

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            ++ K +    ES L    +++     +L+      + A  K   L+     L  E+   
Sbjct: 679 LDSFKNLTFQLES-LEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
              ++ L+   +  E++  S         + LQ  +    K                   
Sbjct: 738 KKGLELLKASFKKTERLEVS-YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTL 796

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
              L+  +  S RL  +E          KEN+  ++ET    +L+  +  L +  + LRQ
Sbjct: 797 QKNLEELKISSKRLEQLE----------KENKSLEQET---SQLEKDKKQLEKENKRLRQ 843

Query: 325 SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME--- 381
               KD+ L   + +  G   E     ++ E+   ++  V+L++   E +E  K      
Sbjct: 844 QAEIKDTTLEE-NNVKIG-NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDI 901

Query: 382 QTMTQYENQLAALRLEVKRLRN 403
           +T+      L + +L+ +++ N
Sbjct: 902 KTLVTLREDLVSEKLKTQQMNN 923



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 66/381 (17%), Positives = 158/381 (41%), Gaps = 21/381 (5%)

Query: 85  LDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           ++RD   KKIE L +EN  L     E ++K++ +   H         +      + +++ 
Sbjct: 396 MERDMDRKKIEELMEENMTL-----EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSL 450

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
              + E+ +S    L +    +     +L+ T    E    K   +E+   RL+ +    
Sbjct: 451 GHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 510

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
             ++ + ++  +  + +++  + E+    + ++      E+   +               
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL 570

Query: 265 XXQLQSFRDRSIRLVDMERR---RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEE- 320
             + Q   +  ++ ++ E +     ++    K ++    + +I KEL+  +    R+EE 
Sbjct: 571 RQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEEL 630

Query: 321 --ELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENE 377
             EL     E +     ++ +    E  E+ + + +   L+RE +  KL++T+D  +   
Sbjct: 631 ENELHHLEKENELLQKKITNLKITCEKIEALEQENSE--LERENR--KLKKTLDSFKNLT 686

Query: 378 KSMEQTMTQYENQLAALRLEVKR-LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTA 436
             +E ++ +  +QL    LE++R + +  C S  ++  +LQ E  +L  + E L ++   
Sbjct: 687 FQLE-SLEKENSQLDEENLELRRNVESLKCASMKMA--QLQLENKELESEKEQL-KKGLE 742

Query: 437 LITAAASRALMLERHERAADL 457
           L+ A+  +   LE   +  D+
Sbjct: 743 LLKASFKKTERLEVSYQGLDI 763


>AB014535-1|BAA31610.2|  864|Homo sapiens KIAA0635 protein protein.
          Length = 864

 Score = 57.6 bits (133), Expect = 9e-08
 Identities = 76/363 (20%), Positives = 146/363 (40%), Gaps = 20/363 (5%)

Query: 90  MIKKIERLQKENSILQHKVDE-TSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
           M K I  + KE   LQ  VDE T K  N +      +      +++   +S+  ++   L
Sbjct: 449 MKKTIGVIDKEKDFLQETVDEKTEKIANLQENLANKEKAVAQMKIM---ISECESSVNQL 505

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
           KE + + +  +   R ++    ++L +     EIA K+++ L+  +  +A E    ++++
Sbjct: 506 KETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQEISLEL 565

Query: 209 KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL 268
           +   ++ E  +      ++E  +R E L A   E+E    +                   
Sbjct: 566 EAAVQEKEEMKSRVHKYITE-VSRWESLMA-AKEKENQDLLDRFQMLHNRAEDWEVKAHQ 623

Query: 269 QSFRDRSIRL----VDMERRRCLEYVPCKENEPTDR---ETEIWKELQMTRGALLRSEEE 321
                 S+RL    +D ERR   E V   E E  +          ++     A+ R EEE
Sbjct: 624 AEGESSSVRLELLSIDTERRHLRERVELLEKEIQEHINAHHAYESQISSMAKAMSRLEEE 683

Query: 322 LRQSRAEKDSFLNSLSRIAQ-----GEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
           LR    EK + LN LS + +       G +    ++ ++ L+ E+ +V+L+    E    
Sbjct: 684 LRHQEDEKATVLNDLSSLRELCIKLDSGKDIMTQQLNSKNLEFERVVVELENVKSESDLL 743

Query: 377 EKSMEQTMTQYEN--QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRER 434
           +K +       +N   L A   + +   +   + KD     L+ ++     ++ + SRE 
Sbjct: 744 KKQLSNERHTVKNLESLLATNRDKEFHSHLTSHEKDTEIQLLKEKLTLSESKLTSQSREN 803

Query: 435 TAL 437
           T L
Sbjct: 804 TML 806


>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
          Length = 1938

 Score = 56.0 bits (129), Expect = 3e-07
 Identities = 75/380 (19%), Positives = 155/380 (40%), Gaps = 23/380 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            R+   +K+ R   E + LQH+    + ++ +      +     N Q + ++L KE++  E
Sbjct: 1171 REAEFQKMRR-DLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKS--E 1227

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
               E+   A ++  +++++ + +ER  +  + +F   K K +   QL++ L ++++    
Sbjct: 1228 LKMEIDDMASNIEALSKSK-SNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQT 1286

Query: 207  KVKELREQAETAEQVAQSRVSEQKART---EFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            +  EL  + E  E +       ++A T   E L+ ++ E+ K+K                
Sbjct: 1287 QNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDL 1346

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEE 321
               Q +  ++    L     +   E    K    TD  + TE  +E +      L+  EE
Sbjct: 1347 LREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1406

Query: 322  LRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRENE 377
              ++   K + L    +  QGE  +  +D      A   LD++Q+         +Q+ +E
Sbjct: 1407 KTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDE 1466

Query: 378  KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
               E    Q E++  +L  E+ ++RN        +Y E+  ++  L  + + L  E + L
Sbjct: 1467 SQAELEAAQKESR--SLSTELFKMRN--------AYEEVVDQLETLRRENKNLQEEISDL 1516

Query: 438  ITAAASRALMLERHERAADL 457
                A     L+  E+   L
Sbjct: 1517 TEQIAETGKNLQEAEKTKKL 1536



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 60/303 (19%), Positives = 123/303 (40%), Gaps = 16/303 (5%)

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +K ++ SAE     A   +AT++   + TK E   ++ + K+LE+ +  L  E++   ++
Sbjct: 840  IKPLLKSAE-----AEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQ 894

Query: 208  VKELREQAETAEQVAQSRVSEQ---KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            V+   E    AE+  +  +  +   +A+ + L  ++ E+E+  +                
Sbjct: 895  VQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSL 954

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               +    + ++  V+ E+      V     E T  E  I K  +  +      ++ L  
Sbjct: 955  KRDIDDL-ELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDD 1013

Query: 325  SRAEKDSFLNSLSRI-----AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
             + E+D  +N L +I      Q +  E   ++      D E+   KL+  +   +E+   
Sbjct: 1014 LQVEEDK-VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMD 1072

Query: 380  MEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALIT 439
            +E    Q E +L     E+ +L+      + V   + Q +I +L  ++E L  E  A  T
Sbjct: 1073 LENEKQQIEEKLKKKEFELSQLQ-ARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHT 1131

Query: 440  AAA 442
              A
Sbjct: 1132 LRA 1134



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 75/404 (18%), Positives = 161/404 (39%), Gaps = 34/404 (8%)

Query: 65   IAENLKAKINFSLEIAKIPWLDRDTMIKKIE-RLQKENSILQHKVDETSK-----KENEE 118
            + E  K+ +  +LE  +      ++ I +++  L +  S L  KV E  +     K N +
Sbjct: 1536 LVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQ 1595

Query: 119  PPCHPVQSG-SYNYQVLNEELSKERAAREALKEV---VASAESMLRVARARIATLERQLK 174
                 +QS      +  N+ L  ++     L E+   +  +   +   +  + T++ QLK
Sbjct: 1596 RAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLK 1655

Query: 175  DTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS-RVSEQKART 233
            D++   + A + ++DL++   +LAI      + ++EL E     EQ  ++ R+SEQ+   
Sbjct: 1656 DSQLHLDDALRSNEDLKE---QLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLD 1712

Query: 234  EFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCK 293
               + ++   + +  +                 Q Q+  + SI+    E R   E     
Sbjct: 1713 ASDRVQLLHSQNTSLI------NTKKKLEADIAQCQAEVENSIQ----ESRNAEEKAKKA 1762

Query: 294  ENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA 353
              +      E+ KE Q T   L R ++ L Q+  +    L+   ++A   G +  Q K+ 
Sbjct: 1763 ITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ-KL- 1819

Query: 354  TELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSY 413
                  E ++ +L+  +D +++      +   +YE ++  +  + +  R      +D+  
Sbjct: 1820 ------ENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNILRLQDL-V 1872

Query: 414  PELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADL 457
             +LQ ++     Q E    +    ++        LE     AD+
Sbjct: 1873 DKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADI 1916


>AK125925-1|BAC86346.1|  623|Homo sapiens protein ( Homo sapiens
           cDNA FLJ43937 fis, clone TESTI4013924. ).
          Length = 623

 Score = 55.6 bits (128), Expect = 4e-07
 Identities = 63/319 (19%), Positives = 141/319 (44%), Gaps = 13/319 (4%)

Query: 92  KKIER-LQKENSILQHKVDETSK--KENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
           KK+ER L+K++  +     + ++  KE +E     + +     + L +EL+     R   
Sbjct: 134 KKLERALEKQSETVDELTGKNNQILKEKDELKTQ-LYAALQQIENLRKELNDVLTKRALQ 192

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
           +E + S E  LR  ++  A LE ++K++       + + K   ++ +++ +E++H   ++
Sbjct: 193 EEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEI 252

Query: 209 KELRE-QAETAEQV--AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXX 265
            EL++ QA+   ++   Q  + +  A    L  K+AE+E++K                  
Sbjct: 253 AELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRD 312

Query: 266 XQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQS 325
            +  +   +     D+ +R   +     ++  T  E  I + ++  +     +E  +R  
Sbjct: 313 EETATIITQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTL 372

Query: 326 RAEKDSFLNSLSRIAQG--EGTESFQDKMATELLDREQKIVKLQ---QTIDEQRENEKSM 380
           +AE     N +++I +G  E  +S  D++  EL   E +  KL+   Q + +Q E  +  
Sbjct: 373 KAESLEEKN-MAKIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEEREKH 431

Query: 381 EQTMTQYENQLAALRLEVK 399
                ++  ++   RL++K
Sbjct: 432 ISIEEEHLRRMEEARLQLK 450



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 55/263 (20%), Positives = 103/263 (39%), Gaps = 25/263 (9%)

Query: 164 ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ 223
           +++  L R+L++ + +      + K+++   +    ER HA +++ EL   AE A + A+
Sbjct: 36  SQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAE 95

Query: 224 SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER 283
             +SE +      +     +E  K  A                  +S R   ++   +E 
Sbjct: 96  RYLSELQQSEALKEEAEKRREDLKLKAQ-----------------ESIRQWKLKHKKLE- 137

Query: 284 RRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
            R LE      +E T +  +I KE    +  L  + +++   R E +  L    R  Q E
Sbjct: 138 -RALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLT--KRALQEE 194

Query: 344 GTESFQDKM---ATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKR 400
              S ++K+    +   D E ++     TI       K   +  +Q + + A L  E+  
Sbjct: 195 ELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAE 254

Query: 401 LRNYDCYSKDVSYPELQTEILDL 423
           L+      K     E+Q  I DL
Sbjct: 255 LKKSQAQDK-AKLLEMQESIKDL 276


>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
           protein.
          Length = 1410

 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 69/308 (22%), Positives = 140/308 (45%), Gaps = 28/308 (9%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAE-FEIAKKKHKDL-EQ 192
           +EEL KE    + L++  A  + ++  + A + +LE+QL++ + E F I  K+ KDL EQ
Sbjct: 106 SEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNI--KQMKDLFEQ 163

Query: 193 LVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
              +LA E +    K  E R   E AEQ   +R++E+  +    +A V +  K++ +   
Sbjct: 164 KAAQLATEIADIKSKYDEERSLREAAEQKV-TRLTEELNK----EATVIQDLKTE-LLQR 217

Query: 253 XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                         Q+Q+  D     + +ER R  E +  +  +   +       +   R
Sbjct: 218 PGIEDVAVLKKELVQVQTLMDN----MTLERERESEKLKDESKKFESQYASSEATISQLR 273

Query: 313 GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
             L +  +E+R    E     +S++ + Q   T      +   LL +EQ   KL++  +E
Sbjct: 274 SELSKGPQEVRVYVQELQKLKSSVNELTQKNQT------LTENLLKKEQDYTKLEEKHNE 327

Query: 373 QRENEKSMEQTM-------TQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
           +  ++K+++ T+        Q +++L+A    + R+ + +   K  +  +L+ E+ ++  
Sbjct: 328 ESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRI-HVELSEKGEATQKLKEELSEVET 386

Query: 426 QVETLSRE 433
           + + L  E
Sbjct: 387 KYQHLKAE 394



 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 66/351 (18%), Positives = 150/351 (42%), Gaps = 20/351 (5%)

Query: 92  KKIERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKE 150
           +K +++Q   ++LQ   +  S  E E    +  +Q+G     VLN+   K    ++ + +
Sbjct: 520 EKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQ 579

Query: 151 VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE 210
           +  + ++     +     L  Q+++ KA    A+ +   LE  VN L  + + +  KV +
Sbjct: 580 LTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQ 639

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
           L  Q +   ++    +S + A+T    A+ A+ +     A                QL  
Sbjct: 640 LDIQIKAKTELL---LSAEAAKT----AQRADLQNHLDTAQNALQDKHQELNKITTQLDQ 692

Query: 271 FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
               + +L D ++  C + +     E  ++   + ++ +   G + + E +  + +A K+
Sbjct: 693 V---TAKLQD-KQEHCSQ-LESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKE 747

Query: 331 SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENE--KSMEQTMTQYE 388
             L  L +  Q       +    ++ L+ E++IV     +D Q+++E  +S++Q +T+ E
Sbjct: 748 QALQDLQQQRQLNTDLELRATELSKQLEMEKEIVS-STRLDLQKKSEALESIKQKLTKQE 806

Query: 389 NQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALIT 439
            +   L+ + + L         + + EL   I     +++ +  E+ AL+T
Sbjct: 807 EEKQILKQDFETLSQ----ETKIQHEELNNRIQTTVTELQKVKMEKEALMT 853



 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 75/335 (22%), Positives = 149/335 (44%), Gaps = 30/335 (8%)

Query: 92   KKIERLQKENSILQHKVDETSKKENEEPPCHPVQSG---SYNYQVLNEELSKERAAREAL 148
            +K E L  E  I + + D    K ++E     +Q     + + ++   ELSK+    E  
Sbjct: 723  QKTEEL--EGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQL---EME 777

Query: 149  KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ---LVNRLAIERSHAT 205
            KE+V+S    L+     + +++++L   + E +I K+  + L Q   + +     R   T
Sbjct: 778  KEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTT 837

Query: 206  VKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            V   +  +  + A     S V ++ ++ ++ L+   +E EK                   
Sbjct: 838  VTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL 897

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
              QLQ   + +++    E ++ LE    KE E +    ++  EL   +  L++++  L+Q
Sbjct: 898  KHQLQVQMENTLK-EQKELKKSLE----KEKEASH---QLKLELNSMQEQLIQAQNTLKQ 949

Query: 325  SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTM 384
            +  E+     +++ + Q     S Q K   E L  E KI  LQ+T     E E  ++Q +
Sbjct: 950  NEKEEQQLQGNINELKQS----SEQKKKQIEALQGELKIAVLQKT-----ELENKLQQQL 1000

Query: 385  TQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
            TQ   +LAA + ++  L+N    S++ ++ +LQ++
Sbjct: 1001 TQAAQELAAEKEKISVLQNNYEKSQE-TFKQLQSD 1034



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 84/410 (20%), Positives = 168/410 (40%), Gaps = 29/410 (7%)

Query: 87  RDTMIKKIERLQKENSILQHKVDET-SKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +D   +K  +L  E + ++ K DE  S +E  E     +         + ++L  E   R
Sbjct: 158 KDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQR 217

Query: 146 EALKEVVASAESMLRVARARI-ATLERQ-----LKDTKAEFEIA-KKKHKDLEQLVNRLA 198
             +++V    + +++V       TLER+     LKD   +FE         + QL + L+
Sbjct: 218 PGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDESKKFESQYASSEATISQLRSELS 277

Query: 199 IERSHATVKVKELREQAETAEQVAQSR--VSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
                  V V+EL++   +  ++ Q    ++E   + E    K+ E+   ++V+      
Sbjct: 278 KGPQEVRVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQA 337

Query: 257 XXXXXXXXXXQLQS---FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRG 313
                     QLQS     + S+  + +E     E     + E ++ ET+ ++ L+    
Sbjct: 338 TLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETK-YQHLKAEFK 396

Query: 314 ALLRSEEELRQSRAEKDSFLNSLS--------RIAQGEGTESFQDKMATE-LLDREQKIV 364
            L +  EE  Q   +  S +N L         ++ +  G    Q ++++E L+D+EQ++ 
Sbjct: 397 QLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVA 456

Query: 365 KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
            LQ  +    E  K      T+ ++QL   + + +  +     S      E Q ++  + 
Sbjct: 457 DLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQ-QSTTAKLREAQNDLEQVL 515

Query: 425 LQV---ETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAAL 471
            Q+   +   +   AL+  +     +LE+ ER  DL+A++     + A L
Sbjct: 516 RQIGEKDQKIQNLEALLQKSKENISLLEK-ER-EDLYAKIQAGEGETAVL 563


>AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
           protein.
          Length = 2442

 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 103/463 (22%), Positives = 186/463 (40%), Gaps = 35/463 (7%)

Query: 32  TLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMI 91
           TL E    S+LE +    E    T  L R    IAE   ++     E+A     D     
Sbjct: 544 TLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVA-----DLRAAA 598

Query: 92  KKIERLQKENSILQHKVDET--SKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            K+  L +  ++ +  +++     +E  +  C  +++       L  +L++    REAL 
Sbjct: 599 VKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALW 658

Query: 150 EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDL--EQLVNRLAIERSHATVK 207
           E     E+ L+ A    A L+  L+D + E E  +KK  +   +Q      +E+ H   K
Sbjct: 659 EKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAK 718

Query: 208 VKELREQAETAEQVAQSRVSEQKARTEFLQA------KVAEQEKSKAVAXXXXXXXXXXX 261
            +E  E    A Q  ++ V E+ A    LQA       +AEQ +  + A           
Sbjct: 719 RQE--EVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEA 776

Query: 262 XXXXXQLQSFRDR---SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRS 318
                 ++  + +    I+ V   +      V C + E     ++  +E       L ++
Sbjct: 777 QQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQA 836

Query: 319 EEE----LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
           E+E    L Q +A  +  +N L    + E     Q ++A  L   E++ ++L+  + EQ+
Sbjct: 837 EQEGKTALEQQKAAHEKEVNQLREKWEKE-RSWHQQELAKALESLEREKMELEMRLKEQQ 895

Query: 375 ENEKSM----EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETL 430
              +++    E+  TQ E+ L  ++LE ++ R     S   +  + Q E+ D   Q+E L
Sbjct: 896 TEMEAIQAQREEERTQAESALCQMQLETEKER----VSLLETLLQTQKELADASQQLERL 951

Query: 431 SRERTA--LITAAASRALMLERHERAADLFARMVRARKDLAAL 471
            ++     L     +  L  +  E   +L     + R DLAAL
Sbjct: 952 RQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAAL 994



 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 73/340 (21%), Positives = 137/340 (40%), Gaps = 31/340 (9%)

Query: 149  KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
            KE     E  L V   R+  LE  L D +AE   ++++ K L  L  + A +     V+ 
Sbjct: 1865 KEQARRLEEELAVEGRRVQALEEVLGDLRAE---SREQEKALLALQQQCAEQAQEHEVET 1921

Query: 209  KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL 268
            + L++    A+ V + R  E +A     Q+   ++E ++A A                + 
Sbjct: 1922 RALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKE 1981

Query: 269  QSFRDR----------------SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
            Q   ++                S+       R+  E +  +E E  D++    +++Q  +
Sbjct: 1982 QHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQ 2041

Query: 313  GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
             AL + +EELR  + E++  L     +AQ       Q+K        E++I  L Q++ E
Sbjct: 2042 QALAQRDEELRHQQ-EREQLLE--KSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRE 2098

Query: 373  QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
                   ++ T+ Q E ++  LR E ++  N +          ++ + L L      L R
Sbjct: 2099 -------LQLTLAQKEQEILELR-ETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQR 2150

Query: 433  ERTALITA-AASRALMLERHERAADLFARMVRARKDLAAL 471
            E   L  A   + A  +E  E+A DL   + + +  +++L
Sbjct: 2151 ELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSL 2190



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 97/471 (20%), Positives = 195/471 (41%), Gaps = 27/471 (5%)

Query: 14   EHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKI 73
            E  A LRD++       + L E R        T+  +   + +R   ++A   +  +A +
Sbjct: 677  ELQADLRDIQEEKEEIQKKLSESRHQQEAA-TTQLEQLHQEAKRQEEVLARAVQEKEALV 735

Query: 74   N--FSLEIA-KIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYN 130
                +LE+  +    DR  + ++++ L     +L+  + E  ++ +       V  G   
Sbjct: 736  REKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS----VIEVTKGQLE 791

Query: 131  YQVLNEELSKERAAREA--LKEVVASAESMLRVAR-ARIATLERQLKDTKAEFEIAKKKH 187
             Q+     +KE    E   LK  + +  S     R A    L +  ++ K   E  K  H
Sbjct: 792  VQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAH 851

Query: 188  -KDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ--E 244
             K++ QL  +   ERS    ++ +  E  E  +   + R+ EQ+   E +QA+  E+  +
Sbjct: 852  EKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQ 911

Query: 245  KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER-RRCLEYVPCKENEPTD-RET 302
               A+                  LQ+ ++ +     +ER R+ ++    KE E T   +T
Sbjct: 912  AESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQT 971

Query: 303  EIWKELQMTRGALLRSEEELRQSRAEKDSFLN---SLSRIAQGEGTESFQDKMATELLDR 359
            ++ +  +  + A  +  ++L   + E  S L     L +  +   ++      +  L+++
Sbjct: 972  QLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQ 1031

Query: 360  E--QKIVKLQQ--TIDEQRENEK-SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP 414
            E  +K+ + Q+   I ++ E EK S+  ++ + E +L  L+ E   +R  +  +      
Sbjct: 1032 EVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQ-EADSIRQQELSALRQDMQ 1090

Query: 415  ELQTEILDLHLQVETLSRE-RTALITAAASRALMLERHERAADLFARMVRA 464
            E Q E  +L  Q+E L +E +       A  A +LE  E A+ +  + +RA
Sbjct: 1091 EAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELE-ASHITEQQLRA 1140



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 90/417 (21%), Positives = 175/417 (41%), Gaps = 30/417 (7%)

Query: 39   LSNLEWKTRNTEFDN-DTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIER- 96
            +++L+ + R  E    + +    ++    ENL A++   L+ A +    + +    +E  
Sbjct: 1322 MASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEH-LQAAVVEARAQASAAGILEED 1380

Query: 97   LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAE 156
            L+   S L+ K +E    E+E      +Q      +V   +  +E  A   L + +A  E
Sbjct: 1381 LRTARSALKLKNEEV---ESERERAQALQEQG-ELKVAQGKALQENLA--LLTQTLAERE 1434

Query: 157  SMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAE 216
              +   R +I  LE+Q +  KA  E+     K   Q V+ L  E+     K + + E   
Sbjct: 1435 EEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVD-LQQEQIQELEKCRSVLEHLP 1493

Query: 217  TAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSI 276
             A Q  + +++ Q+ +   L+    ++E  + V                 Q    +D   
Sbjct: 1494 MAVQEREQKLTVQREQIRELEK---DRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKK 1550

Query: 277  RLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSL 336
            +LV +E   CL     + +   + + ++ KEL+  R     +   L     E+   L + 
Sbjct: 1551 QLVTLE---CLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQ 1607

Query: 337  SRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRL 396
            S  +Q    ES    +A EL +R+Q++   ++ I+E +  ++ + Q + + + +   L L
Sbjct: 1608 S--SQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQE---LML 1662

Query: 397  EVKRLRNYDCYSKDVSYPELQTEILDLHL-QVETLSRERTALITAAASRALMLERHE 452
            + +R++  +           QT+IL+  L Q++   RER   +T    R LM ER E
Sbjct: 1663 QKERIQVLE------DQRTRQTKILEEDLEQIKLSLRERGRELT--TQRQLMQERAE 1711



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 55/246 (22%), Positives = 104/246 (42%), Gaps = 8/246 (3%)

Query: 161  VARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR-EQAETAE 219
            V R ++  LE +L DT+AE      + +DL++ +++   E+S    K   L  E  E  E
Sbjct: 1261 VLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHE 1320

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
             +A  +   ++A  + ++A+  E+E  +A                           I   
Sbjct: 1321 TMASLQSRLRRAELQRMEAQ-GERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEE 1379

Query: 280  DMERRRCLEYVPCKENEPTDRETEIWK---ELQMTRG-ALLRSEEELRQSRAEKDSFLNS 335
            D+   R    +  +E E      +  +   EL++ +G AL  +   L Q+ AE++  + +
Sbjct: 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVET 1439

Query: 336  LSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
            L    Q    +    K A ELL  + K  K  Q +D Q+E  + +E+  +  E+   A++
Sbjct: 1440 LRGQIQELEKQREMQKAALELLSLDLK--KRNQEVDLQQEQIQELEKCRSVLEHLPMAVQ 1497

Query: 396  LEVKRL 401
               ++L
Sbjct: 1498 EREQKL 1503



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 35/124 (28%), Positives = 67/124 (54%), Gaps = 13/124 (10%)

Query: 133  VLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ 192
            VL ++L + R   E LKE   S +S L  A+  +A  +++L+  + E + A+ + + +++
Sbjct: 1782 VLQQQLQEAREQGE-LKE--QSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKE 1838

Query: 193  LVNRL--AIERSHATVK-----VKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAE 242
              + L  A+E++H T+K     +++ +EQA   E+   V   RV   +     L+A+  E
Sbjct: 1839 KADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESRE 1898

Query: 243  QEKS 246
            QEK+
Sbjct: 1899 QEKA 1902



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 61/302 (20%), Positives = 116/302 (38%), Gaps = 22/302 (7%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEE--PPCHPVQSGSYNYQVLNEELSKERA 143
           +RDT+  +   LQ E   L  K  E  +K  EE       ++  ++  + +N EL  +  
Sbjct: 443 ERDTLAGQTVDLQGEVDSLS-KERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGD 501

Query: 144 AREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN-RLAIERS 202
           + +  KE     +  L +A      L+  L   +A      K+ + L +L+  R A+E S
Sbjct: 502 SAQGQKE---EQQEELHLAVRERERLQEMLMGLEA------KQSESLSELITLREALESS 552

Query: 203 HATVKVKELREQAETAEQVAQSR--VSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXX 260
           H   ++   +EQ E    +A++   ++E  +    L+ +VA+   +              
Sbjct: 553 HLEGELLR-QEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALD 611

Query: 261 XXXXXXQLQSFRDRS----IRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                 QL    + +     R+   E+ R    V   E E   R   +W++       L 
Sbjct: 612 KVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEK--RREALWEKNTHLEAQLQ 669

Query: 317 RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
           ++EE   + +A+          I +       Q + AT  L++  +  K Q+ +  +   
Sbjct: 670 KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQ 729

Query: 377 EK 378
           EK
Sbjct: 730 EK 731



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 3/143 (2%)

Query: 314  ALLRSEEELRQSRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDE 372
            AL +  ++L +++  +D   + + ++ +    TE+ + ++ TEL D ++++ + Q+   +
Sbjct: 1244 ALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSK 1303

Query: 373  QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
                + S+E  + +    +A+L+  ++R       ++      LQ    +L  QVE L +
Sbjct: 1304 WEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQG-ERELLQAAKENLTAQVEHL-Q 1361

Query: 433  ERTALITAAASRALMLERHERAA 455
                   A AS A +LE   R A
Sbjct: 1362 AAVVEARAQASAAGILEEDLRTA 1384


>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal
           Nek2-associated protein 1 protein.
          Length = 2442

 Score = 54.8 bits (126), Expect = 7e-07
 Identities = 103/463 (22%), Positives = 186/463 (40%), Gaps = 35/463 (7%)

Query: 32  TLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMI 91
           TL E    S+LE +    E    T  L R    IAE   ++     E+A     D     
Sbjct: 544 TLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVA-----DLRAAA 598

Query: 92  KKIERLQKENSILQHKVDET--SKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            K+  L +  ++ +  +++     +E  +  C  +++       L  +L++    REAL 
Sbjct: 599 VKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALW 658

Query: 150 EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDL--EQLVNRLAIERSHATVK 207
           E     E+ L+ A    A L+  L+D + E E  +KK  +   +Q      +E+ H   K
Sbjct: 659 EKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAK 718

Query: 208 VKELREQAETAEQVAQSRVSEQKARTEFLQA------KVAEQEKSKAVAXXXXXXXXXXX 261
            +E  E    A Q  ++ V E+ A    LQA       +AEQ +  + A           
Sbjct: 719 RQE--EVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEA 776

Query: 262 XXXXXQLQSFRDR---SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRS 318
                 ++  + +    I+ V   +      V C + E     ++  +E       L ++
Sbjct: 777 QQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQA 836

Query: 319 EEE----LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
           E+E    L Q +A  +  +N L    + E     Q ++A  L   E++ ++L+  + EQ+
Sbjct: 837 EQEGKTALEQQKAAHEKEVNQLREKWEKE-RSWHQQELAKALESLEREKMELEMRLKEQQ 895

Query: 375 ENEKSM----EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETL 430
              +++    E+  TQ E+ L  ++LE ++ R     S   +  + Q E+ D   Q+E L
Sbjct: 896 TEMEAIQAQREEERTQAESALCQMQLETEKER----VSLLETLLQTQKELADASQQLERL 951

Query: 431 SRERTA--LITAAASRALMLERHERAADLFARMVRARKDLAAL 471
            ++     L     +  L  +  E   +L     + R DLAAL
Sbjct: 952 RQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAAL 994



 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 73/340 (21%), Positives = 137/340 (40%), Gaps = 31/340 (9%)

Query: 149  KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
            KE     E  L V   R+  LE  L D +AE   ++++ K L  L  + A +     V+ 
Sbjct: 1865 KEQARRLEEELAVEGRRVQALEEVLGDLRAE---SREQEKALLALQQQCAEQAQEHEVET 1921

Query: 209  KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL 268
            + L++    A+ V + R  E +A     Q+   ++E ++A A                + 
Sbjct: 1922 RALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKE 1981

Query: 269  QSFRDR----------------SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
            Q   ++                S+       R+  E +  +E E  D++    +++Q  +
Sbjct: 1982 QHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQ 2041

Query: 313  GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
             AL + +EELR  + E++  L     +AQ       Q+K        E++I  L Q++ E
Sbjct: 2042 QALAQRDEELRHQQ-EREQLLE--KSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRE 2098

Query: 373  QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
                   ++ T+ Q E ++  LR E ++  N +          ++ + L L      L R
Sbjct: 2099 -------LQLTLAQKEQEILELR-ETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQR 2150

Query: 433  ERTALITA-AASRALMLERHERAADLFARMVRARKDLAAL 471
            E   L  A   + A  +E  E+A DL   + + +  +++L
Sbjct: 2151 ELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSL 2190



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 97/471 (20%), Positives = 195/471 (41%), Gaps = 27/471 (5%)

Query: 14   EHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKI 73
            E  A LRD++       + L E R        T+  +   + +R   ++A   +  +A +
Sbjct: 677  ELQADLRDIQEEKEEIQKKLSESRHQQEAA-TTQLEQLHQEAKRQEEVLARAVQEKEALV 735

Query: 74   N--FSLEIA-KIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYN 130
                +LE+  +    DR  + ++++ L     +L+  + E  ++ +       V  G   
Sbjct: 736  REKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS----VIEVTKGQLE 791

Query: 131  YQVLNEELSKERAAREA--LKEVVASAESMLRVAR-ARIATLERQLKDTKAEFEIAKKKH 187
             Q+     +KE    E   LK  + +  S     R A    L +  ++ K   E  K  H
Sbjct: 792  VQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAH 851

Query: 188  -KDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ--E 244
             K++ QL  +   ERS    ++ +  E  E  +   + R+ EQ+   E +QA+  E+  +
Sbjct: 852  EKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQ 911

Query: 245  KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER-RRCLEYVPCKENEPTD-RET 302
               A+                  LQ+ ++ +     +ER R+ ++    KE E T   +T
Sbjct: 912  AESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQT 971

Query: 303  EIWKELQMTRGALLRSEEELRQSRAEKDSFLN---SLSRIAQGEGTESFQDKMATELLDR 359
            ++ +  +  + A  +  ++L   + E  S L     L +  +   ++      +  L+++
Sbjct: 972  QLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQ 1031

Query: 360  E--QKIVKLQQ--TIDEQRENEK-SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP 414
            E  +K+ + Q+   I ++ E EK S+  ++ + E +L  L+ E   +R  +  +      
Sbjct: 1032 EVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQ-EADSIRQQELSALRQDMQ 1090

Query: 415  ELQTEILDLHLQVETLSRE-RTALITAAASRALMLERHERAADLFARMVRA 464
            E Q E  +L  Q+E L +E +       A  A +LE  E A+ +  + +RA
Sbjct: 1091 EAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELE-ASHITEQQLRA 1140



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 90/417 (21%), Positives = 175/417 (41%), Gaps = 30/417 (7%)

Query: 39   LSNLEWKTRNTEFDN-DTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIER- 96
            +++L+ + R  E    + +    ++    ENL A++   L+ A +    + +    +E  
Sbjct: 1322 MASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEH-LQAAVVEARAQASAAGILEED 1380

Query: 97   LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAE 156
            L+   S L+ K +E    E+E      +Q      +V   +  +E  A   L + +A  E
Sbjct: 1381 LRTARSALKLKNEEV---ESERERAQALQEQG-ELKVAQGKALQENLA--LLTQTLAERE 1434

Query: 157  SMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAE 216
              +   R +I  LE+Q +  KA  E+     K   Q V+ L  E+     K + + E   
Sbjct: 1435 EEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVD-LQQEQIQELEKCRSVLEHLP 1493

Query: 217  TAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSI 276
             A Q  + +++ Q+ +   L+    ++E  + V                 Q    +D   
Sbjct: 1494 MAVQEREQKLTVQREQIRELEK---DRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKK 1550

Query: 277  RLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSL 336
            +LV +E   CL     + +   + + ++ KEL+  R     +   L     E+   L + 
Sbjct: 1551 QLVTLE---CLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQ 1607

Query: 337  SRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRL 396
            S  +Q    ES    +A EL +R+Q++   ++ I+E +  ++ + Q + + + +   L L
Sbjct: 1608 S--SQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQE---LML 1662

Query: 397  EVKRLRNYDCYSKDVSYPELQTEILDLHL-QVETLSRERTALITAAASRALMLERHE 452
            + +R++  +           QT+IL+  L Q++   RER   +T    R LM ER E
Sbjct: 1663 QKERIQVLE------DQRTRQTKILEEDLEQIKLSLRERGRELT--TQRQLMQERAE 1711



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 55/246 (22%), Positives = 104/246 (42%), Gaps = 8/246 (3%)

Query: 161  VARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR-EQAETAE 219
            V R ++  LE +L DT+AE      + +DL++ +++   E+S    K   L  E  E  E
Sbjct: 1261 VLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHE 1320

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
             +A  +   ++A  + ++A+  E+E  +A                           I   
Sbjct: 1321 TMASLQSRLRRAELQRMEAQ-GERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEE 1379

Query: 280  DMERRRCLEYVPCKENEPTDRETEIWK---ELQMTRG-ALLRSEEELRQSRAEKDSFLNS 335
            D+   R    +  +E E      +  +   EL++ +G AL  +   L Q+ AE++  + +
Sbjct: 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVET 1439

Query: 336  LSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
            L    Q    +    K A ELL  + K  K  Q +D Q+E  + +E+  +  E+   A++
Sbjct: 1440 LRGQIQELEKQREMQKAALELLSLDLK--KRNQEVDLQQEQIQELEKCRSVLEHLPMAVQ 1497

Query: 396  LEVKRL 401
               ++L
Sbjct: 1498 EREQKL 1503



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 35/124 (28%), Positives = 67/124 (54%), Gaps = 13/124 (10%)

Query: 133  VLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ 192
            VL ++L + R   E LKE   S +S L  A+  +A  +++L+  + E + A+ + + +++
Sbjct: 1782 VLQQQLQEAREQGE-LKE--QSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKE 1838

Query: 193  LVNRL--AIERSHATVK-----VKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAE 242
              + L  A+E++H T+K     +++ +EQA   E+   V   RV   +     L+A+  E
Sbjct: 1839 KADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESRE 1898

Query: 243  QEKS 246
            QEK+
Sbjct: 1899 QEKA 1902



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 61/302 (20%), Positives = 116/302 (38%), Gaps = 22/302 (7%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEE--PPCHPVQSGSYNYQVLNEELSKERA 143
           +RDT+  +   LQ E   L  K  E  +K  EE       ++  ++  + +N EL  +  
Sbjct: 443 ERDTLAGQTVDLQGEVDSLS-KERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGD 501

Query: 144 AREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN-RLAIERS 202
           + +  KE     +  L +A      L+  L   +A      K+ + L +L+  R A+E S
Sbjct: 502 SAQGQKE---DQQEELHLAVRERERLQEMLMGLEA------KQSESLSELITLREALESS 552

Query: 203 HATVKVKELREQAETAEQVAQSR--VSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXX 260
           H   ++   +EQ E    +A++   ++E  +    L+ +VA+   +              
Sbjct: 553 HLEGELLR-QEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALD 611

Query: 261 XXXXXXQLQSFRDRS----IRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                 QL    + +     R+   E+ R    V   E E   R   +W++       L 
Sbjct: 612 KVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEK--RREALWEKNTHLEAQLQ 669

Query: 317 RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
           ++EE   + +A+          I +       Q + AT  L++  +  K Q+ +  +   
Sbjct: 670 KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQ 729

Query: 377 EK 378
           EK
Sbjct: 730 EK 731



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 3/143 (2%)

Query: 314  ALLRSEEELRQSRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDE 372
            AL +  ++L +++  +D   + + ++ +    TE+ + ++ TEL D ++++ + Q+   +
Sbjct: 1244 ALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSK 1303

Query: 373  QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
                + S+E  + +    +A+L+  ++R       ++      LQ    +L  QVE L +
Sbjct: 1304 WEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQG-ERELLQAAKENLTAQVEHL-Q 1361

Query: 433  ERTALITAAASRALMLERHERAA 455
                   A AS A +LE   R A
Sbjct: 1362 AAVVEARAQASAAGILEEDLRTA 1384


>L06148-1|AAA35921.1|  579|Homo sapiens golgin-165 protein.
          Length = 579

 Score = 54.4 bits (125), Expect = 9e-07
 Identities = 97/454 (21%), Positives = 181/454 (39%), Gaps = 42/454 (9%)

Query: 45  KTRNTEFDNDTERLHRMVAGIAENL-KAKINFSLEIAKIPWLDRDTMIKKIERLQKENSI 103
           K+   E D    RL       +E L K +   +++  ++  L ++T   K +  + +   
Sbjct: 17  KSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQF 76

Query: 104 LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVAR 163
           LQ KV   + + +       +       + L+ EL + R     +     +AE+ L    
Sbjct: 77  LQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLH 136

Query: 164 ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH--ATVKVKE-LREQAETAEQ 220
             +A + + + D +   + A+K+  ++E  +  L  ++    A  +  E L++Q E  +Q
Sbjct: 137 REVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQ 196

Query: 221 VAQSRVSEQKARTEFLQAKV--AEQE---KSKA------VAXXXXXXXXXXXXXXXXQLQ 269
            A+  ++EQK +   L + +  A++E   K KA      +                 +L 
Sbjct: 197 EARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELG 256

Query: 270 SFR------DRSIRLVDMERRRCLEY-VPCKENEPTDRETEIWKELQMTRGALLRSEE-- 320
             R      D S+ L   ER + LE  +    +  T  E E+ + + +T   L  S E  
Sbjct: 257 QLRAQGGSSDSSLAL--HERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKV 314

Query: 321 -ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
            EL     E   F   + R+      E    K+A EL   + K+  L Q+    RE+   
Sbjct: 315 LELEDELQESRGFRKKIKRL------EESNKKLALELEHEKGKLTGLGQSNAALREHNSI 368

Query: 380 MEQTMTQYENQLAALRLEVKR-LRNYDCYSKDVSY--PELQTEILDLHLQVETLSRERTA 436
           +E  + + E  L  L L+V+  L+  +   + + +    LQ  +     +V +L  +   
Sbjct: 369 LETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQ--- 425

Query: 437 LITAAASRALMLERHERAADLFARMVRARKDLAA 470
            + AA   A    RH +AA L   +   +K+L A
Sbjct: 426 -VAAAKVEAGHNRRHFKAASL--ELSEVKKELQA 456



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 12/157 (7%)

Query: 132 QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
           Q L   L KE+    +LKE VA+       A+       R  K    E    KK+ +  E
Sbjct: 406 QALQASLEKEKEKVNSLKEQVAA-------AKVEAGHNRRHFKAASLELSEVKKELQAKE 458

Query: 192 QLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAX 251
            LV +L  E     ++++E +   E A+   Q+ ++E +A+ + LQ ++ EQ   + V  
Sbjct: 459 HLVQKLQAEAD--DLQIREGKHSQEIAQ--FQAELAEARAQLQLLQKQLDEQLSKQPVGN 514

Query: 252 XXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE 288
                          ++QS + + + L + + R+ LE
Sbjct: 515 QEMENLKWEVDQKEREIQSLK-QQLDLTEQQGRKELE 550


>D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein.
          Length = 1530

 Score = 54.4 bits (125), Expect = 9e-07
 Identities = 97/454 (21%), Positives = 181/454 (39%), Gaps = 42/454 (9%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENL-KAKINFSLEIAKIPWLDRDTMIKKIERLQKENSI 103
            K+   E D    RL       +E L K +   +++  ++  L ++T   K +  + +   
Sbjct: 786  KSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQF 845

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVAR 163
            LQ KV   + + +       +       + L+ EL + R     +     +AE+ L    
Sbjct: 846  LQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLH 905

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH--ATVKVKE-LREQAETAEQ 220
              +A + + + D +   + A+K+  ++E  +  L  ++    A  +  E L++Q E  +Q
Sbjct: 906  REVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQ 965

Query: 221  VAQSRVSEQKARTEFLQAKV--AEQE---KSKA------VAXXXXXXXXXXXXXXXXQLQ 269
             A+  ++EQK +   L + +  A++E   K KA      +                 +L 
Sbjct: 966  EARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELG 1025

Query: 270  SFR------DRSIRLVDMERRRCLEY-VPCKENEPTDRETEIWKELQMTRGALLRSEE-- 320
              R      D S+ L   ER + LE  +    +  T  E E+ + + +T   L  S E  
Sbjct: 1026 QLRAQGGSSDSSLAL--HERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKV 1083

Query: 321  -ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
             EL     E   F   + R+      E    K+A EL   + K+  L Q+    RE+   
Sbjct: 1084 LELEDELQESRGFRKKIKRL------EESNKKLALELEHEKGKLTGLGQSNAALREHNSI 1137

Query: 380  MEQTMTQYENQLAALRLEVKR-LRNYDCYSKDVSY--PELQTEILDLHLQVETLSRERTA 436
            +E  + + E  L  L L+V+  L+  +   + + +    LQ  +     +V +L  +   
Sbjct: 1138 LETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQ--- 1194

Query: 437  LITAAASRALMLERHERAADLFARMVRARKDLAA 470
             + AA   A    RH +AA L   +   +K+L A
Sbjct: 1195 -VAAAKVEAGHNRRHFKAASL--ELSEVKKELQA 1225



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 98/432 (22%), Positives = 174/432 (40%), Gaps = 46/432 (10%)

Query: 35   EVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKI 94
            E + +   + + R  EF+ + ERL RM      +  A +   LE  K+  L RD   +++
Sbjct: 661  EAKTMVEEDLQRRLEEFEGERERLQRMA-----DSAASLEQQLEQVKLTLLQRD---QQL 712

Query: 95   ERLQKENSILQHKVDETSKK-ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
            E LQ+E+  L  ++  T +  ++ E     +Q+     Q    EL  E A+RE    ++ 
Sbjct: 713  EALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQ 772

Query: 154  SAESMLRVARARIATLERQL-KDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR 212
            + + +L  A     + + +L +  +   E  ++  + LE+L   LAI+      +V+ L 
Sbjct: 773  NEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSG----QVEHL- 827

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
             Q ETA    Q     QK + +FLQ KV  +   +                   +L++ R
Sbjct: 828  -QQETAALKKQM----QKIKEQFLQQKVMVEAYRR---------DATSKDQLISELKATR 873

Query: 273  DRSIRLVDMERRRCLEYVPCKENEPTDRETE---IWKELQMTRGALLRSEEELRQSRAEK 329
             R    +D E +   + +     E    E E   + +E+   R  +   E  L+ ++ E+
Sbjct: 874  KR----LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKER 929

Query: 330  DSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYEN 389
            D     L  + Q +  +      A E L  +++I +LQQ   E R+     +Q M +  +
Sbjct: 930  DEMETHLQSL-QFDKEQMVAVTEANEAL--KKQIEELQQ---EARKAITEQKQKMRRLGS 983

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLE 449
             L + + E+K    +  Y   V    L   + +     E    E   L     S    L 
Sbjct: 984  DLTSAQKEMK--TKHKAYENAVGI--LSRRLQEALAAKEAADAELGQLRAQGGSSDSSLA 1039

Query: 450  RHERAADLFARM 461
             HER   L A +
Sbjct: 1040 LHERIQALEAEL 1051



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 12/157 (7%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            Q L   L KE+    +LKE VA+       A+       R  K    E    KK+ +  E
Sbjct: 1175 QALQASLEKEKEKVNSLKEQVAA-------AKVEAGHNRRHFKAASLELSEVKKELQAKE 1227

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAX 251
             LV +L  E     ++++E +   E A+   Q+ ++E +A+ + LQ ++ EQ   + V  
Sbjct: 1228 HLVQKLQAEAD--DLQIREGKHSQEIAQ--FQAELAEARAQLQLLQKQLDEQLSKQPVGN 1283

Query: 252  XXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE 288
                           ++QS + + + L + + R+ LE
Sbjct: 1284 QEMENLKWEVDQKEREIQSLK-QQLDLTEQQGRKELE 1319



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 51/274 (18%), Positives = 111/274 (40%), Gaps = 14/274 (5%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L   L  + A+  +    +  AE   +   A++  ++R +          +++   L+  
Sbjct: 487 LQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQ 546

Query: 194 VNRLAIERSHATVKVKELREQAETAEQV----AQSRVSEQKARTEFLQAKVAEQEKSKAV 249
           + ++ +ER+  T K+K  + +  + + V     Q     Q+AR   LQ ++A  +  +  
Sbjct: 547 LQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVR-LQGEMAHIQVGQMT 605

Query: 250 AXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ 309
                            QL   + RS++    E+ R    +   E +  D+E   + ++Q
Sbjct: 606 QAGILEHLKLENVSLSQQLTETQHRSMK----EKGRIAAQLQGIEADMLDQEA-AFMQIQ 660

Query: 310 MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGT-ESFQDKMATELLDREQKIVKLQQ 368
             +  +   EE+L++   E +     L R+A    + E   +++   LL R+Q++  LQQ
Sbjct: 661 EAKTMV---EEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQ 717

Query: 369 TIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
              +  +     ++ +   E  L AL+     L+
Sbjct: 718 EHLDLMKQLTLTQEALQSREQSLDALQTHYDELQ 751


>BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein.
          Length = 2002

 Score = 54.4 bits (125), Expect = 9e-07
 Identities = 95/433 (21%), Positives = 193/433 (44%), Gaps = 54/433 (12%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSIL 104
            K RN E   +++RL   ++ +   L  + N     +++  LD +T  +   R +KE   L
Sbjct: 1275 KERN-ELRLNSDRLESRISELTSELTDERNTGESASQL--LDAETAERL--RAEKEMKEL 1329

Query: 105  QHKVDETSKK----ENEEPPCHPVQSGSYNYQVLNEE------LSKERAAREA---LKEV 151
            Q + D   K+    E E      +++   N +V +++      L  ERA RE     K +
Sbjct: 1330 QTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRL 1389

Query: 152  VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVK-- 209
                E  L V +     LER+L D +A+ E +++  + L++   RL  E     + ++  
Sbjct: 1390 QQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQ 1449

Query: 210  ELRE-QAETAEQVAQSRVSE--QKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX 266
            ++R  + E  ++   S +S+  ++A+ E LQ +  ++EK   +A                
Sbjct: 1450 QVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDM-- 1507

Query: 267  QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
             +  F  +   +V +E    L+ +  +E++      ++ K+L+     +   EEEL + +
Sbjct: 1508 DIAGFTQK---VVSLEAE--LQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE-Q 1561

Query: 327  AEKDSFLNSLSRIAQGEGTESFQDKMAT--ELLDREQKIVKLQQTIDEQR-ENEKSMEQT 383
            A     L  L ++ + +  E ++DK     E  + E K+  L   ++ +  E+EK + + 
Sbjct: 1562 AGTIQMLEQLKQM-EVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKD 1620

Query: 384  MTQYENQLAALRL-------------EVKRLRN------YDCYSKDVSYPELQTEILDLH 424
            + + +  LA  +L             E+ +L+N      + C +   +   ++ EI DLH
Sbjct: 1621 LKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLH 1680

Query: 425  LQVETLSRERTAL 437
            LQ++ +++ +TAL
Sbjct: 1681 LQIDDIAKAKTAL 1693



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 12/100 (12%)

Query: 306  KELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVK 365
            +E+Q  R  L ++E+E  + R   D   + +S +      E    + A++LLD E     
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETA--- 1317

Query: 366  LQQTIDEQRENEKSMEQTMTQYE---NQLAALRLEVKRLR 402
                  E+   EK M++  TQY+    Q+  + +EV   R
Sbjct: 1318 ------ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEAR 1351


>AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2
            protein.
          Length = 1390

 Score = 54.4 bits (125), Expect = 9e-07
 Identities = 97/454 (21%), Positives = 181/454 (39%), Gaps = 42/454 (9%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENL-KAKINFSLEIAKIPWLDRDTMIKKIERLQKENSI 103
            K+   E D    RL       +E L K +   +++  ++  L ++T   K +  + +   
Sbjct: 786  KSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQF 845

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVAR 163
            LQ KV   + + +       +       + L+ EL + R     +     +AE+ L    
Sbjct: 846  LQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLH 905

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH--ATVKVKE-LREQAETAEQ 220
              +A + + + D +   + A+K+  ++E  +  L  ++    A  +  E L++Q E  +Q
Sbjct: 906  REVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQ 965

Query: 221  VAQSRVSEQKARTEFLQAKV--AEQE---KSKA------VAXXXXXXXXXXXXXXXXQLQ 269
             A+  ++EQK +   L + +  A++E   K KA      +                 +L 
Sbjct: 966  EARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELG 1025

Query: 270  SFR------DRSIRLVDMERRRCLEY-VPCKENEPTDRETEIWKELQMTRGALLRSEE-- 320
              R      D S+ L   ER + LE  +    +  T  E E+ + + +T   L  S E  
Sbjct: 1026 QLRAQGGSSDSSLAL--HERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKV 1083

Query: 321  -ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
             EL     E   F   + R+      E    K+A EL   + K+  L Q+    RE+   
Sbjct: 1084 LELEDELQESRGFRKKIKRL------EESNKKLALELEHEKGKLTGLGQSNAALREHNSI 1137

Query: 380  MEQTMTQYENQLAALRLEVKR-LRNYDCYSKDVSY--PELQTEILDLHLQVETLSRERTA 436
            +E  + + E  L  L L+V+  L+  +   + + +    LQ  +     +V +L  +   
Sbjct: 1138 LETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQ--- 1194

Query: 437  LITAAASRALMLERHERAADLFARMVRARKDLAA 470
             + AA   A    RH +AA L   +   +K+L A
Sbjct: 1195 -VAAAKVEAGHNRRHFKAASL--ELSEVKKELQA 1225



 Score = 43.6 bits (98), Expect = 0.002
 Identities = 98/432 (22%), Positives = 174/432 (40%), Gaps = 46/432 (10%)

Query: 35   EVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKI 94
            E + +   + + R  EF+ + ERL RM      +  A +   LE  K+  L RD   +++
Sbjct: 661  EAKTMVEEDLQRRLEEFEGERERLQRMA-----DSAASLEQQLEQVKLTLLQRD---QQL 712

Query: 95   ERLQKENSILQHKVDETSKK-ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
            E LQ+E+  L  ++  T +  ++ E     +Q+     Q    EL  E A+RE    ++ 
Sbjct: 713  EALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQ 772

Query: 154  SAESMLRVARARIATLERQL-KDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR 212
            + + +L  A     + + +L +  +   E  ++  + LE+L   LAI+      +V+ L 
Sbjct: 773  NEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSG----QVEHL- 827

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
             Q ETA    Q     QK + +FLQ KV  +   +                   +L++ R
Sbjct: 828  -QQETAALKKQM----QKIKEQFLQQKVMVEAYRR---------DATSKDQLISELKATR 873

Query: 273  DRSIRLVDMERRRCLEYVPCKENEPTDRETE---IWKELQMTRGALLRSEEELRQSRAEK 329
             R    +D E +   + +     E    E E   + +E+   R  +   E  L+ ++ E+
Sbjct: 874  KR----LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKER 929

Query: 330  DSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYEN 389
            D     L  + Q +  +      A E L  +++I +LQQ   E R+     +Q M +  +
Sbjct: 930  DEMETHLQSL-QFDKEQMVAVTEANEAL--KKQIEELQQ---EARKAITEQKQKMRRLGS 983

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLE 449
             L + + E+K    +  Y   V    L   + +     E    E   L     S    L 
Sbjct: 984  DLTSAQKEMK--TKHKAYENAVGI--LSRRLQEALAAKEAADAELGQLRAQGGSSDSSLA 1039

Query: 450  RHERAADLFARM 461
             HER   L A +
Sbjct: 1040 LHERIQALEAEL 1051



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 12/157 (7%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            Q L   L KE+    +LKE VA+       A+       R  K    E    KK+ +  E
Sbjct: 1175 QALQASLEKEKEKVNSLKEQVAA-------AKVEAGHNRRHFKAASLELSEVKKELQAKE 1227

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAX 251
             LV +L  E     ++++E +   E A+   Q+ ++E +A+ + LQ ++ EQ   + V  
Sbjct: 1228 HLVQKLQAEAD--DLQIREGKHSQEIAQ--FQAELAEARAQLQLLQKQLDEQLSKQPVGN 1283

Query: 252  XXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE 288
                           ++QS + + + L + + R+ LE
Sbjct: 1284 QEMENLKWEVDQKEREIQSLK-QQLDLTEQQGRKELE 1319



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 51/274 (18%), Positives = 111/274 (40%), Gaps = 14/274 (5%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L   L  + A+  +    +  AE   +   A++  ++R +          +++   L+  
Sbjct: 487 LQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQ 546

Query: 194 VNRLAIERSHATVKVKELREQAETAEQV----AQSRVSEQKARTEFLQAKVAEQEKSKAV 249
           + ++ +ER+  T K+K  + +  + + V     Q     Q+AR   LQ ++A  +  +  
Sbjct: 547 LQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVR-LQGEMAHIQVGQMT 605

Query: 250 AXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ 309
                            QL   + RS++    E+ R    +   E +  D+E   + ++Q
Sbjct: 606 QAGLLEHLKLENVSLSQQLTETQHRSMK----EKGRIAAQLQGIEADMLDQEA-AFMQIQ 660

Query: 310 MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGT-ESFQDKMATELLDREQKIVKLQQ 368
             +  +   EE+L++   E +     L R+A    + E   +++   LL R+Q++  LQQ
Sbjct: 661 EAKTMV---EEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQ 717

Query: 369 TIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
              +  +     ++ +   E  L AL+     L+
Sbjct: 718 EHLDLMKQLTLTQEALQSREQSLDALQTHYDELQ 751


>AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein.
          Length = 1498

 Score = 54.0 bits (124), Expect = 1e-06
 Identities = 97/454 (21%), Positives = 181/454 (39%), Gaps = 42/454 (9%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENL-KAKINFSLEIAKIPWLDRDTMIKKIERLQKENSI 103
            K+   E D    RL       +E L K +   +++  ++  L ++T   K +  + +   
Sbjct: 786  KSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQF 845

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVAR 163
            LQ KV   + + +       +       + L+ EL + R     +     +AE+ L    
Sbjct: 846  LQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLH 905

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH--ATVKVKE-LREQAETAEQ 220
              +A + + + D +   + A+K+  ++E  +  L  ++    A  +  E L++Q E  +Q
Sbjct: 906  REVAQVRQHMADLEGHLQSAQKERDEVETHLQSLQFDKEQMVAVTEANEALKKQIEELQQ 965

Query: 221  VAQSRVSEQKARTEFLQAKV--AEQE---KSKA------VAXXXXXXXXXXXXXXXXQLQ 269
             A+  ++EQK +   L + +  A++E   K KA      +                 +L 
Sbjct: 966  EARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAREAADAELG 1025

Query: 270  SFR------DRSIRLVDMERRRCLEY-VPCKENEPTDRETEIWKELQMTRGALLRSEE-- 320
              R      D S+ L   ER + LE  +    +  T  E E+ + + +T   L  S E  
Sbjct: 1026 QLRAQGGSSDSSLAL--HERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKV 1083

Query: 321  -ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
             EL     E   F   + R+      E    K+A EL   + K+  L Q+    RE+   
Sbjct: 1084 LELEDELQESRGFRKKIKRL------EESNKKLALELEHEKGKLTGLGQSNAALREHNSI 1137

Query: 380  MEQTMTQYENQLAALRLEVKR-LRNYDCYSKDVSY--PELQTEILDLHLQVETLSRERTA 436
            +E  + + E  L  L L+V+  L+  +   + + +    LQ  +     +V +L  +   
Sbjct: 1138 LETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQ--- 1194

Query: 437  LITAAASRALMLERHERAADLFARMVRARKDLAA 470
             + AA   A    RH +AA L   +   +K+L A
Sbjct: 1195 -VAAAKVEAGHNRRHFKAASL--ELSEVKKELQA 1225



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 98/432 (22%), Positives = 174/432 (40%), Gaps = 46/432 (10%)

Query: 35   EVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKI 94
            E + +   + + R  EF+ + ERL RM      +  A +   LE  K+  L RD   +++
Sbjct: 661  EAKTMVEEDLQRRLEEFEGERERLQRMA-----DSAASLEQQLEQVKLTLLQRD---QQL 712

Query: 95   ERLQKENSILQHKVDETSKK-ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
            E LQ+E+  L  ++  T +  ++ E     +Q+     Q    EL  E A+RE    ++ 
Sbjct: 713  EALQQEHLDLMKQLTLTQEALQSREQSLDALQTRYDELQARLGELQGEAASREDTICLLQ 772

Query: 154  SAESMLRVARARIATLERQL-KDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR 212
            + + +L  A     + + +L +  +   E  ++  + LE+L   LAI+      +V+ L 
Sbjct: 773  NEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSG----QVEHL- 827

Query: 213  EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
             Q ETA    Q     QK + +FLQ KV  +   +                   +L++ R
Sbjct: 828  -QQETAALKKQM----QKIKEQFLQQKVMVEAYRR---------DATSKDQLISELKATR 873

Query: 273  DRSIRLVDMERRRCLEYVPCKENEPTDRETE---IWKELQMTRGALLRSEEELRQSRAEK 329
             R    +D E +   + +     E    E E   + +E+   R  +   E  L+ ++ E+
Sbjct: 874  KR----LDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKER 929

Query: 330  DSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYEN 389
            D     L  + Q +  +      A E L  +++I +LQQ   E R+     +Q M +  +
Sbjct: 930  DEVETHLQSL-QFDKEQMVAVTEANEAL--KKQIEELQQ---EARKAITEQKQKMRRLGS 983

Query: 390  QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLE 449
             L + + E+K    +  Y   V    L   + +     E    E   L     S    L 
Sbjct: 984  DLTSAQKEMK--TKHKAYENAVGI--LSRRLQEALAAREAADAELGQLRAQGGSSDSSLA 1039

Query: 450  RHERAADLFARM 461
             HER   L A +
Sbjct: 1040 LHERIQALEAEL 1051



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 11/112 (9%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            Q L   L KE+    +LKE VA+       A+       R  K    E    KK+ +  E
Sbjct: 1175 QALQASLEKEKEKVNSLKEQVAA-------AKVEAGHNRRHFKAASLELSEVKKELQAKE 1227

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             LV +L  E     ++++E +   E A+   Q+ ++E +A+ + LQ ++ EQ
Sbjct: 1228 HLVQKLQAEAD--DLQIREGKHSQEIAQ--FQAELAEARAQLQLLQKQLDEQ 1275



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 51/274 (18%), Positives = 111/274 (40%), Gaps = 14/274 (5%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L   L  + A+  +    +  AE   +   A++  ++R +          +++   L+  
Sbjct: 487 LQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQ 546

Query: 194 VNRLAIERSHATVKVKELREQAETAEQV----AQSRVSEQKARTEFLQAKVAEQEKSKAV 249
           + ++ +ER+  T K+K  + +  + + V     Q     Q+AR   LQ ++A  +  +  
Sbjct: 547 LQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVR-LQGEMAHIQVGQMT 605

Query: 250 AXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ 309
                            QL   + RS++    E+ R    +   E +  D+E   + ++Q
Sbjct: 606 QAGLLEHLKLENVSLSQQLTETQHRSMK----EKGRIAAQLQGIEADMLDQEA-AFMQIQ 660

Query: 310 MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGT-ESFQDKMATELLDREQKIVKLQQ 368
             +  +   EE+L++   E +     L R+A    + E   +++   LL R+Q++  LQQ
Sbjct: 661 EAKTMV---EEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQ 717

Query: 369 TIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
              +  +     ++ +   E  L AL+     L+
Sbjct: 718 EHLDLMKQLTLTQEALQSREQSLDALQTRYDELQ 751


>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
          Length = 1411

 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 67/350 (19%), Positives = 148/350 (42%), Gaps = 20/350 (5%)

Query: 93  KIERLQKENSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEV 151
           K +++Q   ++LQ   +  S  E E    +  +Q+G     VLN+   K    +E + ++
Sbjct: 521 KDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQL 580

Query: 152 VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
               ++     +     L  Q+++ KA    A+ +   LE  VN L  + + +  KV +L
Sbjct: 581 TEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQL 640

Query: 212 REQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSF 271
             Q +   ++    +S + A+T    A+ A+ +     A                QL   
Sbjct: 641 DIQIKAKTELL---LSAEAAKT----AQRADLQNHLDTAQNALQDKQQELNKITTQLDQV 693

Query: 272 RDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDS 331
              + +L D ++  C + +     E  ++   + ++ +   G + + E +  + +A K+ 
Sbjct: 694 ---TAKLQD-KQEHCSQ-LESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQ 748

Query: 332 FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENE--KSMEQTMTQYEN 389
            L  L +  Q       +    ++ L+ E++IV     +D Q+++E  +S++Q +T+ E 
Sbjct: 749 ALQDLQQQRQLNTDLELRATELSKQLEMEKEIVS-STRLDLQKKSEALESIKQKLTKQEE 807

Query: 390 QLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALIT 439
           +   L+ + + L         + + EL   I     +++ +  E+ AL+T
Sbjct: 808 EKQILKQDFETLSQ----ETKIQHEELNNRIQTTVTELQKVKMEKEALMT 853



 Score = 52.8 bits (121), Expect = 3e-06
 Identities = 71/310 (22%), Positives = 142/310 (45%), Gaps = 32/310 (10%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAE-FEIAKKKHKDL-EQ 192
           +EEL KE    + L++  A  + ++  + A + +LE+QL++ + E F I  K+ KDL EQ
Sbjct: 106 SEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNI--KQMKDLFEQ 163

Query: 193 LVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
              +LA E +    K  E R   E AEQ   +R++E+  +    +A V +  K++ +   
Sbjct: 164 KAAQLATEIADIKSKYDEERSLREAAEQKV-TRLTEELNK----EATVIQDLKTE-LLQR 217

Query: 253 XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYV--PCKENEPTDRETEIWKELQM 310
                         Q+Q+  D     + +ER R  E +   CK+ +     +E    +  
Sbjct: 218 PGIEDVAVLKKELVQVQTLMDN----MTLERERESEKLKDECKKLQSQYASSE--ATISQ 271

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            R  L +  +E+     E     +S++ + Q   T      +   LL +EQ   KL++  
Sbjct: 272 LRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQT------LTENLLKKEQDYTKLEEKH 325

Query: 371 DEQRENEKSMEQTM-------TQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDL 423
           +E+  ++K+++ T+        Q +++L+A    + R+ + +   K  +  +L+ E+ ++
Sbjct: 326 NEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRI-HVELSEKGEATQKLKEELSEV 384

Query: 424 HLQVETLSRE 433
             + + L  E
Sbjct: 385 ETKYQHLKAE 394



 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 75/335 (22%), Positives = 149/335 (44%), Gaps = 30/335 (8%)

Query: 92   KKIERLQKENSILQHKVDETSKKENEEPPCHPVQSG---SYNYQVLNEELSKERAAREAL 148
            +K E L  E  I + + D    K ++E     +Q     + + ++   ELSK+    E  
Sbjct: 723  QKTEEL--EGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQL---EME 777

Query: 149  KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ---LVNRLAIERSHAT 205
            KE+V+S    L+     + +++++L   + E +I K+  + L Q   + +     R   T
Sbjct: 778  KEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTT 837

Query: 206  VKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            V   +  +  + A     S V ++ ++ ++ L+   +E EK                   
Sbjct: 838  VTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL 897

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
              QLQ   + +++    E ++ LE    KE E +    ++  EL   +  L++++  L+Q
Sbjct: 898  KHQLQVQMENTLK-EQKELKKSLE----KEKEASH---QLKLELNSMQEQLIQAQNTLKQ 949

Query: 325  SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTM 384
            +  E+     +++ + Q     S Q K   E L  E KI  LQ+T     E E  ++Q +
Sbjct: 950  NEKEEQQLQGNINELKQS----SEQKKKQIEALQGELKIAVLQKT-----ELENKLQQQL 1000

Query: 385  TQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
            TQ   +LAA + ++  L+N    S++ ++ +LQ++
Sbjct: 1001 TQAAQELAAEKEKISVLQNNYEKSQE-TFKQLQSD 1034



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 83/410 (20%), Positives = 169/410 (41%), Gaps = 29/410 (7%)

Query: 87  RDTMIKKIERLQKENSILQHKVDET-SKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +D   +K  +L  E + ++ K DE  S +E  E     +         + ++L  E   R
Sbjct: 158 KDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQR 217

Query: 146 EALKEVVASAESMLRVARARI-ATLERQLKDTKAEFEIAKKKHK------DLEQLVNRLA 198
             +++V    + +++V       TLER+ +  K + E  K + +       + QL + LA
Sbjct: 218 PGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELA 277

Query: 199 IERSHATVKVKELREQAETAEQVAQSR--VSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
                  V V+EL++   +  ++ Q    ++E   + E    K+ E+   ++V+      
Sbjct: 278 KGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQA 337

Query: 257 XXXXXXXXXXQLQS---FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRG 313
                     QLQS     + S+  + +E     E     + E ++ ET+ ++ L+    
Sbjct: 338 TLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETK-YQHLKAEFK 396

Query: 314 ALLRSEEELRQSRAEKDSFLNSLS--------RIAQGEGTESFQDKMATE-LLDREQKIV 364
            L +  EE  Q   +  S +N L         ++ +  G    Q ++++E L+D+EQ++ 
Sbjct: 397 QLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVA 456

Query: 365 KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
            LQ  +    E  K      T+ ++QL   + + +  +     S      E Q ++  + 
Sbjct: 457 DLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQ-QSTTAKLREAQNDLEQVL 515

Query: 425 LQV---ETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAAL 471
            Q+   +   +   AL+  +     +LE+ ER  DL+A++     + A L
Sbjct: 516 RQIGDKDQKIQNLEALLQKSKENISLLEK-ER-EDLYAKIQAGEGETAVL 563


>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
            chain protein.
          Length = 1939

 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 85/444 (19%), Positives = 184/444 (41%), Gaps = 31/444 (6%)

Query: 6    IAQQNSLLEHYAILR-DMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAG 64
            I QQNS +E   +L   ++ +       + E+      E +T   + +     L R +  
Sbjct: 1089 INQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAE-RTARAKVEKLRSDLSRELEE 1147

Query: 65   IAENLK---AKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPC 121
            I+E L+      +  +E+ K     R+   +K+ R   E + LQH+    + ++      
Sbjct: 1148 ISERLEEAGGATSVQIEMNK----KREAEFQKMRR-DLEEATLQHEATAAALRKKHADSV 1202

Query: 122  HPVQSGSYNYQVLNEELSKERAA-REALKEVVASAESMLRVARARIATLERQLKDTKAEF 180
              +     N Q + ++L KE++  +  L +V ++ E +++ A+A +  + R L+D   E+
Sbjct: 1203 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKVSRTLEDQANEY 1261

Query: 181  EIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE----QVAQSRVSEQKARTEFL 236
             +   K ++ ++ +N    +R+    +  EL  Q E  E    Q+ + ++S  + + E L
Sbjct: 1262 RV---KLEEAQRSLNDFTTQRAKLQTENGELSRQLEEKEALISQLTRGKLSYTQ-QMEDL 1317

Query: 237  QAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENE 296
            + ++ E+ K+K                   Q +   +    L  +  +   E   C+   
Sbjct: 1318 KRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKY 1377

Query: 297  PTD--RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQD---- 350
             TD  + TE  +E +      L+  EE  ++   K S L       Q E  +   D    
Sbjct: 1378 ETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERS 1437

Query: 351  KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
              A   LD++Q+     + + E ++  +  +  +   + +  +L  E+ +L+N   Y + 
Sbjct: 1438 NAAAAALDKKQR--NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN--AYEES 1493

Query: 411  VSYPE-LQTEILDLHLQVETLSRE 433
            + + E  + E  +L  ++  L+ +
Sbjct: 1494 LEHLETFKRENKNLQEEISDLTEQ 1517



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 49/273 (17%), Positives = 112/273 (41%), Gaps = 13/273 (4%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1670

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
            + +  +    +    +++ELR   EQ E + ++A   + E   R + L ++       K 
Sbjct: 1671 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKK 1730

Query: 249  VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                              + ++  +++ + +        E    KE + +     + K +
Sbjct: 1731 KMDADLSQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELK--KEQDTSAHLERMKKNM 1788

Query: 309  QMTRGALLRSEEELRQ--SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            + T   L    +E  Q   +  K       +R+ + EG    + K   E +   +K  + 
Sbjct: 1789 EQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERR 1848

Query: 367  QQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + +  Q E +K   + + + ++ +  L+L+VK
Sbjct: 1849 IKELTYQTEEDK---KNLLRLQDLVDKLQLKVK 1878



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 76/362 (20%), Positives = 146/362 (40%), Gaps = 26/362 (7%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
            AE  K       E  +I      +  ++ E  +K  S+LQ K D   + + E+   +  +
Sbjct: 845  AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                  Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    KK
Sbjct: 905  ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KK 954

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
               DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 955  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 1014

Query: 245  KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER-RRCLE-YVPCKENEPTDRET 302
            +   V                 +    +++ +R+ D+ER +R LE  +   +    D E 
Sbjct: 1015 EEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRM-DLERAKRKLEGDLKLTQESIMDLEN 1073

Query: 303  EIWKELQMTRGALLRSEEELRQ--SRAEKDSF--LNSLSRIAQGEG-TESFQDKMATELL 357
            +   +LQ+    L + E ++ Q  S+ E +    L    ++ + +   E  ++++  E  
Sbjct: 1074 D---KLQLEE-KLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERT 1129

Query: 358  DREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQ 417
             R  K+ KL+   D  RE E+  E+           + +  KR   +    +D+    LQ
Sbjct: 1130 AR-AKVEKLRS--DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQ 1186

Query: 418  TE 419
             E
Sbjct: 1187 HE 1188



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 52/208 (25%), Positives = 98/208 (47%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++  ++ E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1737 SQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1795

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1796 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELEGELEA--EQKRNAESVKGMRKS 1845

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  KK    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1846 -----ERRIKELTYQTEEDKKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1893

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1894 NLSKFRKVQHELDEAEERADIAESQVNK 1921



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 81/441 (18%), Positives = 169/441 (38%), Gaps = 39/441 (8%)

Query: 43   EWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS 102
            EWK +  E  ++ E   +    ++  L     F L+ A       +  ++ +E  ++EN 
Sbjct: 1457 EWKQKYEESQSELESSQKEARSLSTEL-----FKLKNAY------EESLEHLETFKRENK 1505

Query: 103  ILQHKVDETSKKENEEPP-CHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML-R 160
             LQ ++ + +++  E     H ++      +V   EL      + AL+E  AS E    +
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLEL------QSALEEAEASLEHEEGK 1559

Query: 161  VARARI------ATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
            + RA++      A +ER+L +   E E AK+ H   +++V+ L       T      R +
Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH---QRVVDSLQTSLDAET----RSRNE 1612

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
                ++  +  ++E + +        AE +K                      +++  D 
Sbjct: 1613 VLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSLLKDTQIQLDDAVRANDDL 1669

Query: 275  SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLN 334
               +  +ERR  L     +E      +TE  +  ++    L+ + E ++   ++  S +N
Sbjct: 1670 KENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLADRELIETSERVQLLHSQNTSLIN 1727

Query: 335  SLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAA 393
               ++ A     +S  ++   E  + E+K  K         E  K  + T    E     
Sbjct: 1728 QKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLERMKKN 1787

Query: 394  LRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHE- 452
            +   +K L++    ++ ++    + ++  L  +V  L  E  A     A     + + E 
Sbjct: 1788 MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSER 1847

Query: 453  RAADLFARMVRARKDLAALLD 473
            R  +L  +    +K+L  L D
Sbjct: 1848 RIKELTYQTEEDKKNLLRLQD 1868


>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
            protein protein.
          Length = 2442

 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 74/340 (21%), Positives = 138/340 (40%), Gaps = 31/340 (9%)

Query: 149  KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
            KE     E  L V   R+  LE  L D +AE   ++++ K L  L  + A +     V+ 
Sbjct: 1865 KEQARRLEEELAVEGRRVQALEEVLGDLRAE---SREQEKALLALQQQCAEQAQEHEVET 1921

Query: 209  KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL 268
            + L++    A+ V + R  E +A     Q+   ++E ++A A                + 
Sbjct: 1922 RALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKE 1981

Query: 269  QSFRDR----------------SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
            Q   ++                S+       R+  E +  +E E  D++    +++Q  +
Sbjct: 1982 QHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQ 2041

Query: 313  GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
             AL + +EELR  + E++  L     +AQ       Q+K    L   E++I  L Q++ E
Sbjct: 2042 QALAQRDEELRHQQ-EREQLLE--KSLAQRVQENMIQEKQNLGLEREEEEIRGLHQSVRE 2098

Query: 373  QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
                   ++ T+ Q E ++  LR E ++  N +          ++ + L L      L R
Sbjct: 2099 -------LQLTLAQKEQEILELR-ETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQR 2150

Query: 433  ERTALITA-AASRALMLERHERAADLFARMVRARKDLAAL 471
            E   L  A   + A  +E  E+A DL   + + +  +++L
Sbjct: 2151 ELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSL 2190



 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 84/379 (22%), Positives = 152/379 (40%), Gaps = 28/379 (7%)

Query: 114 KENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQL 173
           +E  +  C  +++       L  +L++    REAL E     E+ L+ A    A L+  L
Sbjct: 623 EEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADL 682

Query: 174 KDTKAEFEIAKKKHKDL--EQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKA 231
           +D + E E  +KK  +   +Q      +E+ H   K +E  E    A Q  ++ V E+ A
Sbjct: 683 RDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQE--EVLARAVQEKEALVREKAA 740

Query: 232 RTEFLQAKVAEQE--KSKAVAXXXXXXXXXXXXXXXXQLQSFRDR-------SIRLVDME 282
               LQA   +++   ++                   Q  S  D         I+ V   
Sbjct: 741 LEVRLQAVERDRQDLAAQLQGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQTVTQA 800

Query: 283 RRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE----LRQSRAEKDSFLNSLSR 338
           +      V C + E     ++  +E       L ++E+E    L Q +A  +  +N L  
Sbjct: 801 KEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLRE 860

Query: 339 IAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSM----EQTMTQYENQLAAL 394
             + E     Q ++A  L   E++ ++L+  + EQ+   +++    E+  TQ E+ L  +
Sbjct: 861 KWEKE-RSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQM 919

Query: 395 RLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTA--LITAAASRALMLERHE 452
           +LE ++ R     S   +  + Q E+ D   Q+E L ++     L     +  L  +  E
Sbjct: 920 QLETEKER----VSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQE 975

Query: 453 RAADLFARMVRARKDLAAL 471
              +L     + R DLAAL
Sbjct: 976 AQRELKEAARQHRDDLAAL 994



 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 97/473 (20%), Positives = 200/473 (42%), Gaps = 31/473 (6%)

Query: 14   EHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKI 73
            E  A LRD++       + L E R        T+  +   + +R   ++A   +  +A +
Sbjct: 677  ELQADLRDIQEEKEEIQKKLSESRHQQEAA-TTQLEQLHQEAKRQEEVLARAVQEKEALV 735

Query: 74   N--FSLEIA-KIPWLDRDTMIKKIERLQKENSILQHKVDETSKKEN--EEPPCH---PVQ 125
                +LE+  +    DR  +  +++ L     +L+  + E  ++ +  +EP       +Q
Sbjct: 736  REKAALEVRLQAVERDRQDLAAQLQGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQ 795

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
            + +   +V+  E+   R  +  L    + AE     A  ++A  E++    K   E  K 
Sbjct: 796  TVTQAKEVIQGEV---RCLKLELDTERSQAEQERDAAARQLAQAEQE---GKTALEQQKA 849

Query: 186  KH-KDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ- 243
             H K++ QL  +   ERS    ++ +  E  E  +   + R+ EQ+   E +QA+  E+ 
Sbjct: 850  AHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEER 909

Query: 244  -EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER-RRCLEYVPCKENEPTD-R 300
             +   A+                  LQ+ ++ +     +ER R+ ++    KE E T   
Sbjct: 910  TQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGIL 969

Query: 301  ETEIWKELQMTRGALLRSEEELRQSRAEKDSFLN---SLSRIAQGEGTESFQDKMATELL 357
            +T++ +  +  + A  +  ++L   + E  S L     L +  +   ++      +  L+
Sbjct: 970  QTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLV 1029

Query: 358  DRE--QKIVKLQQ--TIDEQRENEK-SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVS 412
            ++E  +K+ + Q+   I ++ E EK S+  ++ + E +L  L+ E   +R  +  +    
Sbjct: 1030 EQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQ-EADSIRQQELSALRQD 1088

Query: 413  YPELQTEILDLHLQVETLSRE-RTALITAAASRALMLERHERAADLFARMVRA 464
              E Q E  +L  Q+E L +E +       A  A +LE  E A+ +  + +RA
Sbjct: 1089 MQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELE-ASHITEQQLRA 1140



 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 90/417 (21%), Positives = 175/417 (41%), Gaps = 30/417 (7%)

Query: 39   LSNLEWKTRNTEFDN-DTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIER- 96
            +++L+ + R  E    + +    ++    ENL A++   L+ A +    + +    +E  
Sbjct: 1322 MASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEH-LQAAVVEARAQASAAGILEED 1380

Query: 97   LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAE 156
            L+   S L+ K +E    E+E      +Q      +V   +  +E  A   L + +A  E
Sbjct: 1381 LRTARSALKLKNEEV---ESERERAQALQEQG-ELKVAQGKALQENLA--LLTQTLAERE 1434

Query: 157  SMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAE 216
              +   R +I  LE+Q +  KA  E+     K   Q V+ L  E+     K + + E   
Sbjct: 1435 EEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVD-LQQEQIQELEKCRSVLEHLP 1493

Query: 217  TAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSI 276
             A Q  + +++ Q+   E ++    ++E  + V                 Q    +D   
Sbjct: 1494 MAVQEREQKLTVQR---EQIREPEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKK 1550

Query: 277  RLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSL 336
            +LV +E   CL     + +   + + ++ KEL+  R     +   L     E+   L + 
Sbjct: 1551 QLVTLE---CLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQ 1607

Query: 337  SRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRL 396
            S  +Q    ES    +A EL +R+Q++   ++ I+E +  ++ + Q + + + +   L L
Sbjct: 1608 S--SQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQE---LML 1662

Query: 397  EVKRLRNYDCYSKDVSYPELQTEILDLHL-QVETLSRERTALITAAASRALMLERHE 452
            + +R++  +           QT+IL+  L Q++   RER   +T    R LM ER E
Sbjct: 1663 QKERIQVLE------DQRTRQTKILEEDLEQIKLSLRERGRELT--TQRQLMQERAE 1711



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 61/271 (22%), Positives = 113/271 (41%), Gaps = 10/271 (3%)

Query: 138  LSKERAAREALK--EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            LS E  A   LK  + +   +    V R ++  LE +L DT+AE      + +DL++ ++
Sbjct: 1236 LSAEAVASALLKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLS 1295

Query: 196  RLAIERSHATVKVKELR-EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXX 254
            +   E+S    K   L  E  E  E +A  +   ++A  + ++A+  E+E  +A      
Sbjct: 1296 QNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQ-GERELLQAAKENLT 1354

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK---ELQMT 311
                                 I   D+   R    +  +E E      +  +   EL++ 
Sbjct: 1355 AQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVA 1414

Query: 312  RG-ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            +G AL  +   L Q+ AE++  + +L    Q    +    K A ELL  + K  K  Q +
Sbjct: 1415 QGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLK--KRNQEV 1472

Query: 371  DEQRENEKSMEQTMTQYENQLAALRLEVKRL 401
            D Q+E  + +E+  +  E+   A++   ++L
Sbjct: 1473 DLQQEQIQELEKCRSVLEHLPMAVQEREQKL 1503



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 32/143 (22%), Positives = 69/143 (48%), Gaps = 3/143 (2%)

Query: 314  ALLRSEEELRQSRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDE 372
            ALL+  ++L +++  +D   + + ++ +    TE+ + ++ TEL D ++++ + Q+   +
Sbjct: 1244 ALLKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSK 1303

Query: 373  QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
                + S+E  + +    +A+L+  ++R       ++      LQ    +L  QVE L +
Sbjct: 1304 WEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQG-ERELLQAAKENLTAQVEHL-Q 1361

Query: 433  ERTALITAAASRALMLERHERAA 455
                   A AS A +LE   R A
Sbjct: 1362 AAVVEARAQASAAGILEEDLRTA 1384



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 35/124 (28%), Positives = 67/124 (54%), Gaps = 13/124 (10%)

Query: 133  VLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ 192
            VL ++L + R   E LKE   S +S L  A+  +A  +++L+  + E + A+ + + +++
Sbjct: 1782 VLQQQLQEAREQGE-LKE--QSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKE 1838

Query: 193  LVNRL--AIERSHATVK-----VKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAE 242
              + L  A+E++H T+K     +++ +EQA   E+   V   RV   +     L+A+  E
Sbjct: 1839 KADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESRE 1898

Query: 243  QEKS 246
            QEK+
Sbjct: 1899 QEKA 1902


>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
          Length = 2083

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 85/374 (22%), Positives = 154/374 (41%), Gaps = 27/374 (7%)

Query: 83  PWLDRDTMIKKIERLQ---KENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELS 139
           P ++    +K +E LQ   K    L  +  ET +   E+  C  + S     + L E+L 
Sbjct: 125 PVVEDGASVKTLETLQQRVKRQENLLKRCKETIQSHKEQ--CTLLTSEK---EALQEQLD 179

Query: 140 KERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEF--EIAKKKHKDLEQLVNRL 197
           +     E +K++  + ++ L         L  QL+  K     E  ++ H+ LE     +
Sbjct: 180 ERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEI 239

Query: 198 AIERSHA---TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXX 254
           A  RS     T + +ELREQ E +E+ A   +  +KA +   + + A + K KA      
Sbjct: 240 AQLRSRIKQMTTQGEELREQKEKSERAAFEEL--EKALSTAQKTEEARR-KLKAEMDEQI 296

Query: 255 XXXXXXXXXXXXQLQSFRDR-SIRLVDMERRRCLEYVP----CKENEPTDRETEIWKELQ 309
                        LQ    R    +VD+ ++   E +       E E   +E E+ K+LQ
Sbjct: 297 KTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQ 356

Query: 310 MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE-GTESFQDKMATELLDREQKIVKLQQ 368
            TR    + + ++   +++ +    S  +  Q     E  + +    L + E K+  LQQ
Sbjct: 357 -TREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQ 415

Query: 369 TIDEQR----ENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
             +  R    E E S+E+++ + ENQ   L + ++  +N       V   + +TE+  L 
Sbjct: 416 EAETYRTRILELESSLEKSLQENENQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLK 475

Query: 425 LQVETLSRERTALI 438
            Q + L  E   ++
Sbjct: 476 HQQDALWAEELQVL 489



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 57/269 (21%), Positives = 122/269 (45%), Gaps = 22/269 (8%)

Query: 130  NYQVLNEELSKERAAR-EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHK 188
            NY    +   KE   + +  +E+    ++ ++ A  +I TLE Q+   KAE E    K K
Sbjct: 1405 NYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE---TKKK 1461

Query: 189  DLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ-SRVSEQK--ARTEFLQAKVAEQEK 245
            +LE +   L+++     +K  E R ++E+A ++A+  R +EQK  A  + L +++ E+E+
Sbjct: 1462 ELEHV--NLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEE 1519

Query: 246  SKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIW 305
                                 +     +  ++ V+  +   L  VP +  +     TE  
Sbjct: 1520 QYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL-IVP-RSAKNVAAYTE-- 1575

Query: 306  KELQMTRGALLRSEEE----LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
            +E   ++G + ++ EE    L+++  EK+  L  + +  + E T S   +M  +    ++
Sbjct: 1576 QEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQ--EKEETVSSHFEMRCQY---QE 1630

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
            +++KL+    +Q E++  +     + E +
Sbjct: 1631 RLIKLEHAEAKQHEDQSMIGHLQEELEEK 1659



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 66/333 (19%), Positives = 141/333 (42%), Gaps = 30/333 (9%)

Query: 130 NYQVLNEELSKERAAREA-LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHK 188
           +YQ    E +K    + A L++ +   E+   +   ++A +E Q KD   E +  K + +
Sbjct: 660 SYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQ 719

Query: 189 DLEQLVNRLAIERSHATVKVKELREQAET------AEQVAQSRVSEQKARTEFLQAKVAE 242
           DL Q   +L  + S    KVK L +  E+       EQ    ++  +K     LQ +  +
Sbjct: 720 DLMQ---QLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEK-ENMILQMREGQ 775

Query: 243 QEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRET 302
           +++ + +                     F+++  + ++  +++  E     + +  D+E 
Sbjct: 776 KKEIEILTQKLSAKEDSIHILNEEYETKFKNQE-KKMEKVKQKAKEMQETLKKKLLDQEA 834

Query: 303 EIWKELQMTRGALLRSEEE-----LRQSRAEKDSFLNSLSRIA--QGEGTESFQDKMATE 355
           ++ KEL+ T   L + E++     L  ++A      +++SR+   Q E  ES  +    E
Sbjct: 835 KLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRE 894

Query: 356 LLD----REQKIVKLQQTIDEQRENE-KSMEQTMTQYENQLAALRLEVKRLRNYDCYSK- 409
           L D     E+K+ +  + + E  E + +  EQ + + + ++     E + +     + K 
Sbjct: 895 LNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKE 954

Query: 410 -----DVSYPELQTEILDLHLQVETLSRERTAL 437
                D +  ELQ ++      V +L+++ T L
Sbjct: 955 EGVKQDTTLNELQEQLKQKSAHVNSLAQDETKL 987



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 55/323 (17%), Positives = 139/323 (43%), Gaps = 18/323 (5%)

Query: 106 HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARAR 165
           H+  E  ++E  +      Q  +   ++  ++   ERAA E L++ +++A+      R  
Sbjct: 229 HETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKL 288

Query: 166 IATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSR 225
            A ++ Q+K  +   + ++++   L+Q ++R  +++    V  K   EQ    +++ +  
Sbjct: 289 KAEMDEQIKTIE---KTSEEERISLQQELSR--VKQEVVDVMKKSSEEQIAKLQKLHEKE 343

Query: 226 VS-EQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR 284
           ++ +++  T+ LQ +  E ++   VA                Q +S    ++  ++++++
Sbjct: 344 LARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESL---ALEELELQKK 400

Query: 285 RCLEYVPCKENE-PTDRETEIWKELQMTRGALLRSEEELRQSR-------AEKDSFLNSL 336
             L     K  +   + ET   + L++        +E   QS+       AEK+     +
Sbjct: 401 AILTESENKLRDLQQEAETYRTRILELESSLEKSLQENENQSKDLAVHLEAEKNKHNKEI 460

Query: 337 SRIAQGEGTESFQDKMATELLDREQ-KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
           + + +   TE    K   + L  E+ +++K Q   + ++  EK  ++  T  +++    +
Sbjct: 461 TVMVEKHKTELESLKHQQDALWAEELQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQ 520

Query: 396 LEVKRLRNYDCYSKDVSYPELQT 418
             ++ +        DV+  EL++
Sbjct: 521 AHIEEMNEKTLEKLDVNQTELES 543



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 63/314 (20%), Positives = 121/314 (38%), Gaps = 17/314 (5%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLV 194
            EE++KE      LKE     ++ L   + ++      + ++ A+ E   K H + LE  +
Sbjct: 943  EEMNKEITW---LKEEGVKQDTTLNELQEQLKQKSAHV-NSLAQDETKLKAHLEKLEVDL 998

Query: 195  NRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXX 254
            N+   E +    ++ EL+  AE  ++      S+ K   E  Q+  +  EKS        
Sbjct: 999  NKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKS 1058

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGA 314
                        QL     ++  L++ +    +     K N    R +         + A
Sbjct: 1059 LEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEA 1118

Query: 315  LL-------RSEEELRQSRAEKDSFLNSLSRIA-QGEGTESFQDKMATELLDREQKIVKL 366
            LL         E +LRQ   E+++   S  +   Q E  E+    M  ++     +   L
Sbjct: 1119 LLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEAL 1178

Query: 367  QQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQ 426
            Q+    Q++     E  +TQ + +L+   +    L   +   K V    L  ++ DL++Q
Sbjct: 1179 QKEGGNQQQAASEKESCITQLKKELSE-NINAVTLMKEELKEKKVEISSLSKQLTDLNVQ 1237

Query: 427  VE---TLSRERTAL 437
            ++   +LS +  A+
Sbjct: 1238 LQNSISLSEKEAAI 1251



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 73/391 (18%), Positives = 154/391 (39%), Gaps = 42/391 (10%)

Query: 101  NSILQHKVDETSKKENEEPPCHP-VQSGSYNYQVLNEELSKERAAREALKEVVASAESML 159
            N   Q    +  +KEN+       ++S     + L +E   ++ A    +  +   +  L
Sbjct: 1144 NISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKEL 1203

Query: 160  RVARARIATLERQLKDTKAEFEIAKKKHKDLE-QLVNRLAIERSHATVKVKELREQAETA 218
                  +  ++ +LK+ K E     K+  DL  QL N +++    A +    LR+Q +  
Sbjct: 1204 SENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAIS--SLRKQYDEE 1261

Query: 219  EQVAQSRVSEQKARTEFL-QAKVAEQE------------KSKAVAXXXXXXXXXXXXXXX 265
            +     +V +   + + L + K++  E            K KA +               
Sbjct: 1262 KCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQ 1321

Query: 266  XQLQSF----RDRSIRLVDMERRRCLEYVPCKENEPTD-------RETEIWKELQMTRGA 314
             +L+S     +D  I L+  E  +  +   C + E  D       +E+ +  EL+     
Sbjct: 1322 LELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTAR 1381

Query: 315  LLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            ++  E+ + Q   E +S    L    Q +  E        EL+   QK+   Q+  +E+ 
Sbjct: 1382 IMELEDHITQKTIEIESLNEVLKNYNQQKDIEH------KELV---QKLQHFQELGEEKD 1432

Query: 375  ENEKSMEQTMTQYENQLAALRLEVK-RLRNYDCYSKDVSYPELQTEILDLHLQVETLSR- 432
               K  E+ +   ENQ+ +++ E++ + +  +  +  V   E + + L+  L+ E+ ++ 
Sbjct: 1433 NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1492

Query: 433  ---ERTALITAAASRALMLERHERAADLFAR 460
               +R A    AA +  +L + E   + + +
Sbjct: 1493 AELKRKAEQKIAAIKKQLLSQMEEKEEQYKK 1523



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 65/321 (20%), Positives = 133/321 (41%), Gaps = 18/321 (5%)

Query: 86   DRDTMIKKIER--LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERA 143
            ++D  +K+ E   L  EN +   K +  +KK+  E     V+S     + L + L  E A
Sbjct: 1430 EKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA 1489

Query: 144  AREALKEVVASAESMLRVARARIATL-----ERQLKDTKAEFEIAKKKHKDLEQLVNRLA 198
            A+  L E+   AE  +   + ++ +      E+  K T++       K ++ E+ V+ L 
Sbjct: 1490 AK--LAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILE 1547

Query: 199  IERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXX 258
             +         E      +A+ VA +   +++A ++    K  E++ S            
Sbjct: 1548 EKLKSVESSQSETLIVPRSAKNVA-AYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKL 1606

Query: 259  XXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMT--RGALL 316
                    +        +R    ER   LE+   K++E       + +EL+    + +L+
Sbjct: 1607 LQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLI 1666

Query: 317  RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMAT-ELLDREQKIVKLQQTIDEQRE 375
             ++   ++          +L  +   +  ++ Q+K  T ++L  EQKI +L   +  Q+E
Sbjct: 1667 VAQHVEKEGGKNNIQAKQNLENVFD-DVQKTLQEKELTCQIL--EQKIKELDSCLVRQKE 1723

Query: 376  -NEKSMEQTMTQYENQLAALR 395
             +   ME+  ++YE +L AL+
Sbjct: 1724 VHRVEMEELTSKYE-KLQALQ 1743



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 87/425 (20%), Positives = 167/425 (39%), Gaps = 38/425 (8%)

Query: 3   KNLIAQ--QNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR 60
           KNLI Q  Q+  +      R M     +  E + ++R     +  T+  E     E+  R
Sbjct: 207 KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIK-QMTTQGEELREQKEKSER 265

Query: 61  MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIER--------LQKENSILQHKVDETS 112
                 E   +    + E  +    + D  IK IE+        LQ+E S ++ +V +  
Sbjct: 266 AAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM 325

Query: 113 KKENEEP-----PCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES-MLRVARARI 166
           KK +EE        H  +      ++  +  ++ER  +E +K  +  ++S  L++++   
Sbjct: 326 KKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQ--- 382

Query: 167 ATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRV 226
              E++ +++ A  E+  +K   L +  N+L   +  A      + E   + E+  Q   
Sbjct: 383 ---EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENE 439

Query: 227 SEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX-----XXQLQSFRDRSIRLVDM 281
           ++ K     L+A+  +  K   V                      +LQ  + +    ++ 
Sbjct: 440 NQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWAEELQVLKQQYQTEMEK 499

Query: 282 ERRRCLEYVPCKENEPTDRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLS 337
            R +C +    KE    D+E      I +  + T   L  ++ EL    +E    L +  
Sbjct: 500 LREKCEQE---KETLLKDKEIIFQAHIEEMNEKTLEKLDVNQTELESLSSELSEVLKARH 556

Query: 338 RIAQGEGTESFQ-DKMATELLDR--EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAAL 394
           ++ +       Q DKM  EL  +  EQK    QQ     +E+E S+++T    ++Q+  L
Sbjct: 557 KLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQL 616

Query: 395 RLEVK 399
            L +K
Sbjct: 617 ELLLK 621


>BC048203-1|AAH48203.1|  663|Homo sapiens Unknown (protein for
           IMAGE:4139784) protein.
          Length = 663

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 96/449 (21%), Positives = 179/449 (39%), Gaps = 42/449 (9%)

Query: 50  EFDNDTERLHRMVAGIAENL-KAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV 108
           E D    RL       +E L K +   +++  ++  L ++T   K +  + +   LQ KV
Sbjct: 3   ELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKV 62

Query: 109 DETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIAT 168
              + + +       +       + L+ EL + R     +     +AE+ L      +A 
Sbjct: 63  MVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQ 122

Query: 169 LERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH--ATVKVKE-LREQAETAEQVAQSR 225
           + + + D +   + A+K+  ++E  +  L  ++    A  +  E L++Q E  +Q A+  
Sbjct: 123 VRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKA 182

Query: 226 VSEQKARTEFLQAKV--AEQE---KSKA------VAXXXXXXXXXXXXXXXXQLQSFR-- 272
           ++EQK +   L + +  A++E   K KA      +                 +L   R  
Sbjct: 183 ITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQ 242

Query: 273 ----DRSIRLVDMERRRCLEY-VPCKENEPTDRETEIWKELQMTRGALLRSEE---ELRQ 324
               D S+ L   ER + LE  +    +  T  E E+ + + +T   L  S E   EL  
Sbjct: 243 GGSSDSSLAL--HERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELED 300

Query: 325 SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTM 384
              E   F   + R+      E    K+A EL   + K+  L Q+    RE+   +E  +
Sbjct: 301 ELQESRGFRKKIKRL------EESNKKLALELEHEKGKLTGLGQSNAALREHNSILETAL 354

Query: 385 TQYENQLAALRLEVKR-LRNYDCYSKDVSY--PELQTEILDLHLQVETLSRERTALITAA 441
            + E  L  L L+V+  L+  +   + + +    LQ  +     +V +L  +    + AA
Sbjct: 355 AKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQ----VAAA 410

Query: 442 ASRALMLERHERAADLFARMVRARKDLAA 470
              A    RH +AA L   +   +K+L A
Sbjct: 411 KVEAGHNRRHFKAASL--ELSEVKKELQA 437



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 12/157 (7%)

Query: 132 QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
           Q L   L KE+    +LKE VA+       A+       R  K    E    KK+ +  E
Sbjct: 387 QALQASLEKEKEKVNSLKEQVAA-------AKVEAGHNRRHFKAASLELSEVKKELQAKE 439

Query: 192 QLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAX 251
            LV +L  E     ++++E +   E A+   Q+ ++E +A+ + LQ ++ EQ   + V  
Sbjct: 440 HLVQKLQAEAD--DLQIREGKHSQEIAQ--FQAELAEARAQLQLLQKQLDEQLSKQPVGN 495

Query: 252 XXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE 288
                          ++QS + + + L + + R+ LE
Sbjct: 496 QEMENLKWEVDQKEREIQSLK-QQLDLTEQQGRKELE 531


>BC014109-1|AAH14109.1|  670|Homo sapiens leucine rich repeat
           containing 45 protein.
          Length = 670

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 77/354 (21%), Positives = 152/354 (42%), Gaps = 23/354 (6%)

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           EE++K   A  A    V   +  L    + I  L+ +L+ T+A   ++++K +DL +L+ 
Sbjct: 271 EEMAKSSRASAAR---VGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLA 327

Query: 196 RLAIER-SHATVKVKELR-EQAETAEQVAQ--SRVSEQKARTEFLQAKVAEQEKSKAVAX 251
               E+ S +  + KEL+ EQ E AE+ ++    +S    +   LQ +V E E+      
Sbjct: 328 TAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQ 387

Query: 252 XXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMT 311
                          +L+    ++   +DME+RRC + +   E+        + + L+ +
Sbjct: 388 EQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEES 447

Query: 312 RGALLRSEEELRQSRAEKDSFLNSLSRIA---QGEGTESFQDKMATELLDREQKIVKLQ- 367
             A+    + L  +R   +  L+ +   A   +G+  E      +   L+ +Q++  L+ 
Sbjct: 448 EKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLED 507

Query: 368 ------QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL-RNYDCYSKDVSYPELQTEI 420
                 Q  DE +      +Q + + + +++ L L+V+ L R  +   +++S  + +   
Sbjct: 508 KLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVA 567

Query: 421 LDLHLQVETLSRERTALITAAASRALMLERHERAADLFARM-VRARKDLAALLD 473
               ++VE   +        AA  AL     E+AA L  ++ V A     ALLD
Sbjct: 568 EVSRVRVELQEQNGRLQAELAAQEAL----REKAAALERQLKVMASDHREALLD 617



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 60/309 (19%), Positives = 131/309 (42%), Gaps = 20/309 (6%)

Query: 90  MIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQV--LNEELSKERA--AR 145
           +++ +    ++N +LQ++VDE  +K      C   Q      ++  ++ EL K RA  A 
Sbjct: 358 LLRDLSAANEKNLLLQNQVDELERKFR----CQQEQLFQTRQEMTSMSAEL-KMRAIQAE 412

Query: 146 EAL-KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
           E L  E     +S+      RI  +E   +  +   +  +++ + LE    RL++E   +
Sbjct: 413 ERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLE--AARLSLEEELS 470

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            VK   L E+ +  E++ +++ S+ +   +   A + ++ +  A A              
Sbjct: 471 RVKAAALSERGQAEEELIKAK-SQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQV 529

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEY---VPCKENEPTDRETEIWKELQMTRGALLRSEEE 321
             + Q+   +    V+  RRR  E    +  K+ E     + +  ELQ   G  L++E  
Sbjct: 530 VAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGR-LQAELA 588

Query: 322 LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ---KIVKLQQTIDEQRENEK 378
            +++  EK + L    ++   +  E+  D+ +     RE+   +  ++ +  DE+ +   
Sbjct: 589 AQEALREKAAALERQLKVMASDHREALLDRESENASLREKLRLREAEIARIRDEEAQRAS 648

Query: 379 SMEQTMTQY 387
            ++  +  Y
Sbjct: 649 FLQNAVLAY 657


>AL132765-6|CAC10587.1|  977|Homo sapiens ribosome binding protein 1
           homolog 180kDa (dog) protein.
          Length = 977

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 98/414 (23%), Positives = 175/414 (42%), Gaps = 36/414 (8%)

Query: 3   KNLIAQQNSLLEHYAILRDM--ESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR 60
           K L  +Q       + LR++  E  A  A    GE +V   L    R  E    T    R
Sbjct: 274 KLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLV--AREQEI---TAVQAR 328

Query: 61  MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEP 119
           M A   E++K       +I  +     +    ++ RLQ+ENSIL+  +++ TS+ E+++ 
Sbjct: 329 MQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQ- 387

Query: 120 PCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAE 179
                   +     L +ELSK         E V   E   +   A+ A  E+Q+   +A 
Sbjct: 388 --------NAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQAS 439

Query: 180 FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
               ++  + L++ ++ ++ E  H       LR  AE A++  Q +++E  ++ +  +A+
Sbjct: 440 H---RESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQE-QQQQMAELHSKLQSSEAE 495

Query: 240 VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIR-LVDMERRRCLEYVPCKENEPT 298
           V    +SK                   QL   R RSI  L++  + R  + V   + E  
Sbjct: 496 V----RSKCEELSGLHGQLQEARAENSQLTE-RIRSIEALLEAGQARDAQDVQASQAEAD 550

Query: 299 DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLD 358
            ++T + KEL+     L +   ELR++  E+    N+  R    +  E+    +AT    
Sbjct: 551 QQQTRL-KELESQVSGLEKEAIELREA-VEQQKVKNNDLREKNWKAMEA----LATAEQA 604

Query: 359 REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAAL-RLEVKRLRNYDCYSKDV 411
            ++K++ L Q   E+ E +  + +  T  E  LA L  L V   +NY  + +D+
Sbjct: 605 CKEKLLSLTQA-KEESEKQLCLIEAQTM-EALLALLPELSVLAQQNYTEWLQDL 656


>AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protein 1
            homolog 180kDa (dog) protein.
          Length = 1410

 Score = 53.2 bits (122), Expect = 2e-06
 Identities = 98/414 (23%), Positives = 175/414 (42%), Gaps = 36/414 (8%)

Query: 3    KNLIAQQNSLLEHYAILRDM--ESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR 60
            K L  +Q       + LR++  E  A  A    GE +V   L    R  E    T    R
Sbjct: 707  KLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLV--AREQEI---TAVQAR 761

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEP 119
            M A   E++K       +I  +     +    ++ RLQ+ENSIL+  +++ TS+ E+++ 
Sbjct: 762  MQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQ- 820

Query: 120  PCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAE 179
                    +     L +ELSK         E V   E   +   A+ A  E+Q+   +A 
Sbjct: 821  --------NAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQAS 872

Query: 180  FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
                ++  + L++ ++ ++ E  H       LR  AE A++  Q +++E  ++ +  +A+
Sbjct: 873  H---RESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQE-QQQQMAELHSKLQSSEAE 928

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIR-LVDMERRRCLEYVPCKENEPT 298
            V    +SK                   QL   R RSI  L++  + R  + V   + E  
Sbjct: 929  V----RSKCEELSGLHGQLQEARAENSQLTE-RIRSIEALLEAGQARDAQDVQASQAEAD 983

Query: 299  DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLD 358
             ++T + KEL+     L +   ELR++  E+    N+  R    +  E+    +AT    
Sbjct: 984  QQQTRL-KELESQVSGLEKEAIELREA-VEQQKVKNNDLREKNWKAMEA----LATAEQA 1037

Query: 359  REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAAL-RLEVKRLRNYDCYSKDV 411
             ++K++ L Q   E+ E +  + +  T  E  LA L  L V   +NY  + +D+
Sbjct: 1038 CKEKLLSLTQA-KEESEKQLCLIEAQTM-EALLALLPELSVLAQQNYTEWLQDL 1089


>BC115701-1|AAI15702.1|  828|Homo sapiens SLMAP protein protein.
          Length = 828

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 100/477 (20%), Positives = 184/477 (38%), Gaps = 44/477 (9%)

Query: 1   MRKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFD-----NDT 55
           +RK LIA Q    +H       ES   V  E +  VR LS +E    NTE +        
Sbjct: 236 LRKELIALQED--KHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMN 293

Query: 56  ERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKE 115
           ER    +  +A      +N   +++    +      +  ++ Q E   LQHK+DE  +KE
Sbjct: 294 ERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKE 353

Query: 116 NEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKD 175
            E      +++   +    NE L+  +   E L+E                ++LE  L  
Sbjct: 354 QELQA--KIEALQADNDFTNERLTALQVRLEHLQEKTLK----------ECSSLEHLLSK 401

Query: 176 TKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE------Q 229
           +  +       H+ +E    +L +E  H T  V+E +   E   +  +S  S+      +
Sbjct: 402 SGGDCTFI---HQFIE-CQKKLIVE-GHLTKAVEETKLSKENQTRAKESDFSDTLSPSKE 456

Query: 230 KARTEFLQAKVAEQEKSKAVAXXXXXXX----XXXXXXXXXQLQSFRDRSIRLVDMER-- 283
           K+  +   A++ EQ+ ++ +A                    ++Q  R   I   ++ R  
Sbjct: 457 KSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTS 516

Query: 284 -RRCLEYVPCKENEPT---DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSL--S 337
            ++C E     E E     ++  E  K++Q+ +  L R   +    R EKDS + S    
Sbjct: 517 KQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDE 576

Query: 338 RIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLE 397
            ++  +         A    +R+  I  LQ+ + + R   +   +  ++YE ++ +L+  
Sbjct: 577 LLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNS 636

Query: 398 VKRLRNYDCYSKD-VSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHER 453
             +LR   C  +       LQ E+  L  +   L  E  +L       +  L+R E+
Sbjct: 637 F-QLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEK 692


>AY517555-1|AAT44528.1|  941|Homo sapiens hypothetical
           rhabdomyosarcoma antigen MU-RMS-40.3 protein.
          Length = 941

 Score = 52.4 bits (120), Expect = 3e-06
 Identities = 74/358 (20%), Positives = 149/358 (41%), Gaps = 26/358 (7%)

Query: 87  RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
           R+    K+ R   E + LQH+    + ++        +     N Q + ++L KE++  E
Sbjct: 169 REAEFLKLRR-DLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKS--E 225

Query: 147 ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
              E+   + SM  V++++ A LE+  +  + +   A+ K++++++ ++ L  ++S    
Sbjct: 226 FKLEIDDLSSSMESVSKSK-ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQT 284

Query: 207 KVKELREQAETAEQVAQSRVSEQK----ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
           +  EL  Q E  E +  S++S  K     +TE L+ ++ E+ K+K               
Sbjct: 285 EAGELSRQLEEKESIV-SQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCD 343

Query: 263 XXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEE 320
               Q +  ++    L     +   E    +    TD  + TE  +E +      L+  E
Sbjct: 344 LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSE 403

Query: 321 ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN-EKS 379
           E  ++   K + L    +  QGE           +L+   ++   L   +D+++ N +K 
Sbjct: 404 EQVEAVNAKCASLEKTKQRLQGE---------VEDLMVDVERANSLAAALDKKQRNFDKV 454

Query: 380 MEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
           + +  T+ E   A L   +K  R+    ++         E LD   Q+ET+ RE   L
Sbjct: 455 LAEWKTKCEESQAELEASLKESRSLS--TELFKLKNAYEEALD---QLETVKRENKNL 507



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 85/398 (21%), Positives = 158/398 (39%), Gaps = 32/398 (8%)

Query: 70  KAKINFSLEIAKIPWLDRDTMIKKIE-RLQKENSILQHKVDETSK-----KENEEPPCHP 123
           KA I  +LE A+      +  I +I+  L +  S +  K+ E  +     K N +     
Sbjct: 539 KADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVET 598

Query: 124 VQSG-SYNYQVLNEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAE 179
           +QS      +  NE +  ++     L E+   ++ A          + +++ QLKDT+  
Sbjct: 599 MQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLH 658

Query: 180 FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
            + A +  +DL++   +LAI    A +   E+ E   T EQ  ++R   + A  E L + 
Sbjct: 659 LDDALRGQEDLKE---QLAIVERRANLLQAEVEELRATLEQTERAR---KLAEQELLDSN 712

Query: 240 VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD 299
             E+ +                     QLQS     +     + R   E       +   
Sbjct: 713 --ERVQLLHTQNTSLIHTKKKLETDLMQLQS----EVEDASRDARNAEEKAKKAITDAAM 766

Query: 300 RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR 359
              E+ KE Q T   L R ++ L Q+  +    L+   ++A   G +  Q K+ T + + 
Sbjct: 767 MAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ-KLETRIREL 824

Query: 360 EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
           E ++        EQ++N +S+ + + +YE ++  L  + +  R      +D+   +LQ +
Sbjct: 825 EFELE------GEQKKNTESV-KGLRKYERRVKELTYQSEEDRKNVLRLQDL-VDKLQVK 876

Query: 420 ILDLHLQVETLSRERTALITAAASRALMLERHERAADL 457
           +     Q E    +  A +T        LE  E  AD+
Sbjct: 877 VKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 914



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 66/352 (18%), Positives = 143/352 (40%), Gaps = 30/352 (8%)

Query: 132 QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
           Q   ++++     +  L++ V   ES L   +     LER  +  + + ++A++   DLE
Sbjct: 13  QAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLE 72

Query: 192 ----QLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
               QL  RL  ++     +++   E  +T     Q ++ E +AR E L+ ++  +  ++
Sbjct: 73  NDKQQLDERLK-KKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATR 131

Query: 248 AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE 307
           A                  +L+     +   +++ ++R  E++  + +     E  +  E
Sbjct: 132 AKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDL---EEATLQHE 188

Query: 308 LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
             +   A LR +     S AE    +++L R+ Q         K+  E  + + +I  L 
Sbjct: 189 AMV---ATLRKKH--ADSVAELGEQIDNLQRVKQ---------KLEKEKSEFKLEIDDLS 234

Query: 368 QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
            +++   +++ ++E+     E+QL+  R + + ++             LQTE  +L  Q+
Sbjct: 235 SSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQR-SLSELTTQKSRLQTEAGELSRQL 293

Query: 428 E-------TLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALL 472
           E        LSR + A           LE   +A +  A  +++ +    LL
Sbjct: 294 EEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLL 345


>BC128578-1|AAI28579.1|  751|Homo sapiens RRBP1 protein protein.
          Length = 751

 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 98/414 (23%), Positives = 174/414 (42%), Gaps = 36/414 (8%)

Query: 3   KNLIAQQNSLLEHYAILRDM--ESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR 60
           K L  +Q       + LR++  E  A  A    GE +V   L    R  E    T    R
Sbjct: 48  KLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLV--AREQEI---TAVQAR 102

Query: 61  MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEP 119
           M A   E++K       +I  +     +    ++ RLQ+ENSIL+  +++ TS+ E+++ 
Sbjct: 103 MQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQ- 161

Query: 120 PCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAE 179
                   +     L +ELSK         E V   E   +   A+ A  E+Q+   +A 
Sbjct: 162 --------NAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQAS 213

Query: 180 FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
               ++  + L++ ++ ++ E  H       LR  AE A++  Q +++E  ++ +  +A+
Sbjct: 214 H---RESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQE-QQQQMAELHSKLQSSEAE 269

Query: 240 VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIR-LVDMERRRCLEYVPCKENEPT 298
           V    +SK                   QL   R RSI  L++  + R  + V   + E  
Sbjct: 270 V----RSKCEELSGLHGQLQEARAENSQLTE-RIRSIEALLEAGQARDAQDVQASQAEAD 324

Query: 299 DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLD 358
            ++T + KEL+     L +   ELR++  E+    N+  R    +  E+    +AT    
Sbjct: 325 QQQTRL-KELESQVSGLEKEAIELREA-VEQQKVKNNDLREKNWKAMEA----LATAEQA 378

Query: 359 REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAAL-RLEVKRLRNYDCYSKDV 411
            ++K+  L Q   E+ E +  + +  T  E  LA L  L V   +NY  + +D+
Sbjct: 379 CKEKLHSLTQA-KEESEKQLCLIEAQTM-EALLALLPELSVLAQQNYTEWLQDL 430


>BC128577-1|AAI28578.1|  934|Homo sapiens RRBP1 protein protein.
          Length = 934

 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 98/414 (23%), Positives = 174/414 (42%), Gaps = 36/414 (8%)

Query: 3   KNLIAQQNSLLEHYAILRDM--ESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR 60
           K L  +Q       + LR++  E  A  A    GE +V   L    R  E    T    R
Sbjct: 231 KLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLV--AREQEI---TAVQAR 285

Query: 61  MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEP 119
           M A   E++K       +I  +     +    ++ RLQ+ENSIL+  +++ TS+ E+++ 
Sbjct: 286 MQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQ- 344

Query: 120 PCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAE 179
                   +     L +ELSK         E V   E   +   A+ A  E+Q+   +A 
Sbjct: 345 --------NAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQAS 396

Query: 180 FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
               ++  + L++ ++ ++ E  H       LR  AE A++  Q +++E  ++ +  +A+
Sbjct: 397 H---RESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQE-QQQQMAELHSKLQSSEAE 452

Query: 240 VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIR-LVDMERRRCLEYVPCKENEPT 298
           V    +SK                   QL   R RSI  L++  + R  + V   + E  
Sbjct: 453 V----RSKCEELSGLHGQLQEARAENSQLTE-RIRSIEALLEAGQARDAQDVQASQAEAD 507

Query: 299 DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLD 358
            ++T + KEL+     L +   ELR++  E+    N+  R    +  E+    +AT    
Sbjct: 508 QQQTRL-KELESQVSGLEKEAIELREA-VEQQKVKNNDLREKNWKAMEA----LATAEQA 561

Query: 359 REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAAL-RLEVKRLRNYDCYSKDV 411
            ++K+  L Q   E+ E +  + +  T  E  LA L  L V   +NY  + +D+
Sbjct: 562 CKEKLHSLTQA-KEESEKQLCLIEAQTM-EALLALLPELSVLAQQNYTEWLQDL 613


>AF006751-1|AAC25977.1|  977|Homo sapiens ES/130 protein.
          Length = 977

 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 98/414 (23%), Positives = 174/414 (42%), Gaps = 36/414 (8%)

Query: 3   KNLIAQQNSLLEHYAILRDM--ESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR 60
           K L  +Q       + LR++  E  A  A    GE +V   L    R  E    T    R
Sbjct: 274 KLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLV--AREQEI---TAVQAR 328

Query: 61  MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEP 119
           M A   E++K       +I  +     +    ++ RLQ+ENSIL+  +++ TS+ E+++ 
Sbjct: 329 MQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQ- 387

Query: 120 PCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAE 179
                   +     L +ELSK         E V   E   +   A+ A  E+Q+   +A 
Sbjct: 388 --------NAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQAS 439

Query: 180 FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
               ++  + L++ ++ ++ E  H       LR  AE A++  Q +++E  ++ +  +A+
Sbjct: 440 H---RESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQE-QQQQMAELHSKLQSSEAE 495

Query: 240 VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIR-LVDMERRRCLEYVPCKENEPT 298
           V    +SK                   QL   R RSI  L++  + R  + V   + E  
Sbjct: 496 V----RSKCEELSGLHGQLQEARAENSQLTE-RIRSIEALLEAGQARDAQDVQASQAEAD 550

Query: 299 DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLD 358
            ++T + KEL+     L +   ELR++  E+    N+  R    +  E+    +AT    
Sbjct: 551 QQQTRL-KELESQVSGLEKEAIELREA-VEQQKVKNNDLREKNWKAMEA----LATAEQA 604

Query: 359 REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAAL-RLEVKRLRNYDCYSKDV 411
            ++K+  L Q   E+ E +  + +  T  E  LA L  L V   +NY  + +D+
Sbjct: 605 CKEKLHSLTQA-KEESEKQLCLIEAQTM-EALLALLPELSVLAQQNYTEWLQDL 656


>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
          Length = 1047

 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 68/307 (22%), Positives = 124/307 (40%), Gaps = 11/307 (3%)

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA--LKEVVASAESMLRV 161
            LQ+++DE  +K   E      Q      +     L+  +   E   ++E +   +     
Sbjct: 716  LQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDE 775

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET-AEQ 220
            A  +   LE+ LKD + E E       D  +LV ++  + S   ++++E R  ++  +E+
Sbjct: 776  ALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSER 835

Query: 221  VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
            +++SR   ++ R E LQ + A Q+                      +  S+R     LV 
Sbjct: 836  ISRSREQMEQVRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE-GSYRSSKEGLVV 894

Query: 281  MERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEEL-RQSRAEKDSFLNSLSRI 339
                R  E     E+E  DR       LQ++   L R  +EL  Q   E  S  +   ++
Sbjct: 895  QMEARIAELEDRLESEERDRAN-----LQLSNRRLERKVKELVMQVDDEHLSLTDQKDQL 949

Query: 340  AQGEGTESFQDKMATELLDR-EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +        Q + A E +DR E    KLQ+ ++EQ +  + ++  +   +  L   +L  
Sbjct: 950  SLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPS 1009

Query: 399  KRLRNYD 405
            K L + D
Sbjct: 1010 KVLDDMD 1016



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 58/275 (21%), Positives = 114/275 (41%), Gaps = 11/275 (4%)

Query: 165 RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE---LREQAETAEQV 221
           R+A L+RQ++D K +   AK+  K  E  + +L     HA  + KE    R   E   + 
Sbjct: 589 RVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEA 648

Query: 222 AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
           AQ  +S+     + L  K+ E+ + K                    ++  +     +V+ 
Sbjct: 649 AQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEA 708

Query: 282 ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
            R   LE     +N+  + + +  +EL   +  L     E  +SR       + + R+ +
Sbjct: 709 SRTSTLEL----QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM-RLME 763

Query: 342 GE--GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
            E    +  QD+  T+    EQ +  L+  ++ +   +    + + Q E++++ L +E++
Sbjct: 764 EELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELE 823

Query: 400 RLR-NYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
             R N D  S+ +S    Q E +   L  E  +R+
Sbjct: 824 EERNNSDLLSERISRSREQMEQVRNELLQERAARQ 858



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 59/346 (17%), Positives = 145/346 (41%), Gaps = 15/346 (4%)

Query: 95  ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
           E L++  + LQ ++++   K +E      ++      + L E L   R   +       +
Sbjct: 584 EELERRVAQLQRQIEDL--KGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRA 641

Query: 155 AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
            E+ L  A+  ++   ++ K    + +   ++ + L +L N +  ER H    +++L  Q
Sbjct: 642 LENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKL--Q 699

Query: 215 AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
            E A+ V  SR S  + + +  + K   ++  + +A                +L + + +
Sbjct: 700 KEMADIVEASRTSTLELQNQLDEYK---EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 756

Query: 275 S-IRLVDMERRRCLEYVPCKENEPTDRET--EIWKELQMTRGALLRSEEELRQSRAEKDS 331
             +RL++ E R   +Y   ++   T R+   +  K+L+    A    +++  +   + + 
Sbjct: 757 DEMRLMEEELR---DYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMED 813

Query: 332 FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ L    + E   S  D ++  +    +++ +++  + ++R   + +E      E Q 
Sbjct: 814 KVSQLEMELEEERNNS--DLLSERISRSREQMEQVRNELLQERAARQDLECDKISLERQN 871

Query: 392 AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
             L+  +  L      SK+    +++  I +L  ++E+  R+R  L
Sbjct: 872 KDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANL 917



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 44/208 (21%), Positives = 94/208 (45%), Gaps = 13/208 (6%)

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
           QL+    ++I+      R  LE +  + NE  +  + + + L+ + G L ++ EEL Q +
Sbjct: 376 QLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVK 435

Query: 327 AEKDSFLNSLSRIAQGEGTESFQD-KMATELLDRE-----QKIVKLQQTIDEQRENEKSM 380
            E++     + R  Q + +E   +   A    DRE     +++++ +Q + +    ++  
Sbjct: 436 MEREQHQTEI-RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQ 494

Query: 381 EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLS-RERTALIT 439
           E  + + E +L AL+  +K     +  S D    +L+ E  D  LQ    S  E T  + 
Sbjct: 495 EDLLRKRERELTALKGALKE----EVSSHDQEMDKLK-EQYDAELQALRESVEEATKNVE 549

Query: 440 AAASRALMLERHERAADLFARMVRARKD 467
             ASR+   E+ +   ++  ++++   +
Sbjct: 550 VLASRSNTSEQDQAGTEMRVKLLQEENE 577



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 8/139 (5%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           DR  ++K     Q E+ + Q +++   ++ N +     +       + +  EL +ERAAR
Sbjct: 803 DRSRLVK-----QMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQVRNELLQERAAR 857

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHA 204
           + L+    S E   +  ++RI  LE   + +K    +  +    + +L +RL + ER  A
Sbjct: 858 QDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEAR--IAELEDRLESEERDRA 915

Query: 205 TVKVKELREQAETAEQVAQ 223
            +++   R + +  E V Q
Sbjct: 916 NLQLSNRRLERKVKELVMQ 934


>AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein.
          Length = 1586

 Score = 51.6 bits (118), Expect = 6e-06
 Identities = 98/414 (23%), Positives = 174/414 (42%), Gaps = 36/414 (8%)

Query: 3    KNLIAQQNSLLEHYAILRDM--ESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR 60
            K L  +Q       + LR++  E  A  A    GE +V   L    R  E    T    R
Sbjct: 883  KLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLV--AREQEI---TAVQAR 937

Query: 61   MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEP 119
            M A   E++K       +I  +     +    ++ RLQ+ENSIL+  +++ TS+ E+++ 
Sbjct: 938  MQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQ- 996

Query: 120  PCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAE 179
                    +     L +ELSK         E V   E   +   A+ A  E+Q+   +A 
Sbjct: 997  --------NAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQAS 1048

Query: 180  FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
                ++  + L++ ++ ++ E  H       LR  AE A++  Q +++E  ++ +  +A+
Sbjct: 1049 H---RESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQE-QQQQMAELHSKLQSSEAE 1104

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIR-LVDMERRRCLEYVPCKENEPT 298
            V    +SK                   QL   R RSI  L++  + R  + V   + E  
Sbjct: 1105 V----RSKCEELSGLHGQLQEARAENSQLTE-RIRSIEALLEAGQARDAQDVQASQAEAD 1159

Query: 299  DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLD 358
             ++T + KEL+     L +   ELR++  E+    N+  R    +  E+    +AT    
Sbjct: 1160 QQQTRL-KELESQVSGLEKEAIELREA-VEQQKVKNNDLREKNWKAMEA----LATAEQA 1213

Query: 359  REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAAL-RLEVKRLRNYDCYSKDV 411
             ++K+  L Q   E+ E +  + +  T  E  LA L  L V   +NY  + +D+
Sbjct: 1214 CKEKLHSLTQA-KEESEKQLCLIEAQTM-EALLALLPELSVLAQQNYTEWLQDL 1265


>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
          Length = 1302

 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 59/275 (21%), Positives = 114/275 (41%), Gaps = 11/275 (4%)

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE---LREQAETAEQV 221
            R+A L+RQ++D K +   AK+  K  E  + +L     HA  + KE    R   E   + 
Sbjct: 844  RVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEA 903

Query: 222  AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
            AQ  +S+     + L  K+ E+ + K                    ++  +     +V+ 
Sbjct: 904  AQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEA 963

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
             R   LE     +N+  + + +  +EL   +  L     E  +SR       + + R+ +
Sbjct: 964  SRTSTLEL----QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM-RLME 1018

Query: 342  GE--GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             E    +  QD+  T+    EQ +  L+  ++ +   +    + + Q E++++ L +E++
Sbjct: 1019 EELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELE 1078

Query: 400  RLR-NYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
              R N D  S+ +S    Q E L   L  E  +R+
Sbjct: 1079 EERNNSDLLSERISRSREQMEQLRNELLQERAARQ 1113



 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 68/307 (22%), Positives = 124/307 (40%), Gaps = 11/307 (3%)

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA--LKEVVASAESMLRV 161
            LQ+++DE  +K   E      Q      +     L+  +   E   ++E +   +     
Sbjct: 971  LQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDE 1030

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET-AEQ 220
            A  +   LE+ LKD + E E       D  +LV ++  + S   ++++E R  ++  +E+
Sbjct: 1031 ALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSER 1090

Query: 221  VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
            +++SR   ++ R E LQ + A Q+                      +  S+R     LV 
Sbjct: 1091 ISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE-GSYRSSKEGLVV 1149

Query: 281  MERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEEL-RQSRAEKDSFLNSLSRI 339
                R  E     E+E  DR       LQ++   L R  +EL  Q   E  S  +   ++
Sbjct: 1150 QMEARIAELEDRLESEERDRAN-----LQLSNRRLERKVKELVMQVDDEHLSLTDQKDQL 1204

Query: 340  AQGEGTESFQDKMATELLDR-EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +        Q + A E +DR E    KLQ+ ++EQ +  + ++  +   +  L   +L  
Sbjct: 1205 SLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPS 1264

Query: 399  KRLRNYD 405
            K L + D
Sbjct: 1265 KVLDDMD 1271



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 60/346 (17%), Positives = 145/346 (41%), Gaps = 15/346 (4%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
            E L++  + LQ ++++   K +E      ++      + L E L   R   +       +
Sbjct: 839  EELERRVAQLQRQIEDL--KGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRA 896

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E+ L  A+  ++   ++ K    + +   ++ + L +L N +  ER H    +++L  Q
Sbjct: 897  LENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKL--Q 954

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
             E A+ V  SR S  + + +  + K   ++  + +A                +L + + +
Sbjct: 955  KEMADIVEASRTSTLELQNQLDEYK---EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011

Query: 275  S-IRLVDMERRRCLEYVPCKENEPTDRET--EIWKELQMTRGALLRSEEELRQSRAEKDS 331
              +RL++ E R   +Y   ++   T R+   +  K+L+    A    +++  +   + + 
Sbjct: 1012 DEMRLMEEELR---DYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMED 1068

Query: 332  FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
             ++ L    + E   S  D ++  +    +++ +L+  + ++R   + +E      E Q 
Sbjct: 1069 KVSQLEMELEEERNNS--DLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQN 1126

Query: 392  AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
              L+  +  L      SK+    +++  I +L  ++E+  R+R  L
Sbjct: 1127 KDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANL 1172



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 44/208 (21%), Positives = 94/208 (45%), Gaps = 13/208 (6%)

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
           QL+    ++I+      R  LE +  + NE  +  + + + L+ + G L ++ EEL Q +
Sbjct: 631 QLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVK 690

Query: 327 AEKDSFLNSLSRIAQGEGTESFQD-KMATELLDRE-----QKIVKLQQTIDEQRENEKSM 380
            E++     + R  Q + +E   +   A    DRE     +++++ +Q + +    ++  
Sbjct: 691 MEREQHQTEI-RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQ 749

Query: 381 EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLS-RERTALIT 439
           E  + + E +L AL+  +K     +  S D    +L+ E  D  LQ    S  E T  + 
Sbjct: 750 EDLLRKRERELTALKGALKE----EVSSHDQEMDKLK-EQYDAELQALRESVEEATKNVE 804

Query: 440 AAASRALMLERHERAADLFARMVRARKD 467
             ASR+   E+ +   ++  ++++   +
Sbjct: 805 VLASRSNTSEQDQAGTEMRVKLLQEENE 832



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 8/139 (5%)

Query: 86   DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
            DR  ++K     Q E+ + Q +++   ++ N +     +       + L  EL +ERAAR
Sbjct: 1058 DRSRLVK-----QMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAAR 1112

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHA 204
            + L+    S E   +  ++RI  LE   + +K    +  +    + +L +RL + ER  A
Sbjct: 1113 QDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEAR--IAELEDRLESEERDRA 1170

Query: 205  TVKVKELREQAETAEQVAQ 223
             +++   R + +  E V Q
Sbjct: 1171 NLQLSNRRLERKVKELVMQ 1189


>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
          Length = 1302

 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 59/275 (21%), Positives = 114/275 (41%), Gaps = 11/275 (4%)

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE---LREQAETAEQV 221
            R+A L+RQ++D K +   AK+  K  E  + +L     HA  + KE    R   E   + 
Sbjct: 844  RVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEA 903

Query: 222  AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
            AQ  +S+     + L  K+ E+ + K                    ++  +     +V+ 
Sbjct: 904  AQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEA 963

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
             R   LE     +N+  + + +  +EL   +  L     E  +SR       + + R+ +
Sbjct: 964  SRTSTLEL----QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM-RLME 1018

Query: 342  GE--GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             E    +  QD+  T+    EQ +  L+  ++ +   +    + + Q E++++ L +E++
Sbjct: 1019 EELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELE 1078

Query: 400  RLR-NYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
              R N D  S+ +S    Q E L   L  E  +R+
Sbjct: 1079 EERNNSDLLSERISRSREQMEQLRNELLQERAARQ 1113



 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 68/307 (22%), Positives = 124/307 (40%), Gaps = 11/307 (3%)

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA--LKEVVASAESMLRV 161
            LQ+++DE  +K   E      Q      +     L+  +   E   ++E +   +     
Sbjct: 971  LQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDE 1030

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET-AEQ 220
            A  +   LE+ LKD + E E       D  +LV ++  + S   ++++E R  ++  +E+
Sbjct: 1031 ALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSER 1090

Query: 221  VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
            +++SR   ++ R E LQ + A Q+                      +  S+R     LV 
Sbjct: 1091 ISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE-GSYRSSKEGLVV 1149

Query: 281  MERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEEL-RQSRAEKDSFLNSLSRI 339
                R  E     E+E  DR       LQ++   L R  +EL  Q   E  S  +   ++
Sbjct: 1150 QMEARIAELEDRLESEERDRAN-----LQLSNRRLERKVKELVMQVDDEHLSLTDQKDQL 1204

Query: 340  AQGEGTESFQDKMATELLDR-EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +        Q + A E +DR E    KLQ+ ++EQ +  + ++  +   +  L   +L  
Sbjct: 1205 SLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPS 1264

Query: 399  KRLRNYD 405
            K L + D
Sbjct: 1265 KVLDDMD 1271



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 60/346 (17%), Positives = 145/346 (41%), Gaps = 15/346 (4%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
            E L++  + LQ ++++   K +E      ++      + L E L   R   +       +
Sbjct: 839  EELERRVAQLQRQIEDL--KGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRA 896

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E+ L  A+  ++   ++ K    + +   ++ + L +L N +  ER H    +++L  Q
Sbjct: 897  LENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKL--Q 954

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
             E A+ V  SR S  + + +  + K   ++  + +A                +L + + +
Sbjct: 955  KEMADIVEASRTSTLELQNQLDEYK---EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011

Query: 275  S-IRLVDMERRRCLEYVPCKENEPTDRET--EIWKELQMTRGALLRSEEELRQSRAEKDS 331
              +RL++ E R   +Y   ++   T R+   +  K+L+    A    +++  +   + + 
Sbjct: 1012 DEMRLMEEELR---DYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMED 1068

Query: 332  FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
             ++ L    + E   S  D ++  +    +++ +L+  + ++R   + +E      E Q 
Sbjct: 1069 KVSQLEMELEEERNNS--DLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQN 1126

Query: 392  AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
              L+  +  L      SK+    +++  I +L  ++E+  R+R  L
Sbjct: 1127 KDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANL 1172



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 44/208 (21%), Positives = 94/208 (45%), Gaps = 13/208 (6%)

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
           QL+    ++I+      R  LE +  + NE  +  + + + L+ + G L ++ EEL Q +
Sbjct: 631 QLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVK 690

Query: 327 AEKDSFLNSLSRIAQGEGTESFQD-KMATELLDRE-----QKIVKLQQTIDEQRENEKSM 380
            E++     + R  Q + +E   +   A    DRE     +++++ +Q + +    ++  
Sbjct: 691 MEREQHQTEI-RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQ 749

Query: 381 EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLS-RERTALIT 439
           E  + + E +L AL+  +K     +  S D    +L+ E  D  LQ    S  E T  + 
Sbjct: 750 EDLLRKRERELTALKGALKE----EVSSHDQEMDKLK-EQYDAELQALRESVEEATKNVE 804

Query: 440 AAASRALMLERHERAADLFARMVRARKD 467
             ASR+   E+ +   ++  ++++   +
Sbjct: 805 VLASRSNTSEQDQAGTEMRVKLLQEENE 832



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 8/139 (5%)

Query: 86   DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
            DR  ++K     Q E+ + Q +++   ++ N +     +       + L  EL +ERAAR
Sbjct: 1058 DRSRLVK-----QMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAAR 1112

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHA 204
            + L+    S E   +  ++RI  LE   + +K    +  +    + +L +RL + ER  A
Sbjct: 1113 QDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEAR--IAELEDRLESEERDRA 1170

Query: 205  TVKVKELREQAETAEQVAQ 223
             +++   R + +  E V Q
Sbjct: 1171 NLQLSNRRLERKVKELVMQ 1189


>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
          Length = 1302

 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 59/275 (21%), Positives = 114/275 (41%), Gaps = 11/275 (4%)

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE---LREQAETAEQV 221
            R+A L+RQ++D K +   AK+  K  E  + +L     HA  + KE    R   E   + 
Sbjct: 844  RVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEA 903

Query: 222  AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
            AQ  +S+     + L  K+ E+ + K                    ++  +     +V+ 
Sbjct: 904  AQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEA 963

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
             R   LE     +N+  + + +  +EL   +  L     E  +SR       + + R+ +
Sbjct: 964  SRTSTLEL----QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM-RLME 1018

Query: 342  GE--GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             E    +  QD+  T+    EQ +  L+  ++ +   +    + + Q E++++ L +E++
Sbjct: 1019 EELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELE 1078

Query: 400  RLR-NYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
              R N D  S+ +S    Q E L   L  E  +R+
Sbjct: 1079 EERNNSDLLSERISRSREQMEQLRNELLQERAARQ 1113



 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 68/307 (22%), Positives = 124/307 (40%), Gaps = 11/307 (3%)

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA--LKEVVASAESMLRV 161
            LQ+++DE  +K   E      Q      +     L+  +   E   ++E +   +     
Sbjct: 971  LQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDE 1030

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET-AEQ 220
            A  +   LE+ LKD + E E       D  +LV ++  + S   ++++E R  ++  +E+
Sbjct: 1031 ALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSER 1090

Query: 221  VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
            +++SR   ++ R E LQ + A Q+                      +  S+R     LV 
Sbjct: 1091 ISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE-GSYRSSKEGLVV 1149

Query: 281  MERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEEL-RQSRAEKDSFLNSLSRI 339
                R  E     E+E  DR       LQ++   L R  +EL  Q   E  S  +   ++
Sbjct: 1150 QMEARIAELEDRLESEERDRAN-----LQLSNRRLERKVKELVMQVDDEHLSLTDQKDQL 1204

Query: 340  AQGEGTESFQDKMATELLDR-EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +        Q + A E +DR E    KLQ+ ++EQ +  + ++  +   +  L   +L  
Sbjct: 1205 SLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPS 1264

Query: 399  KRLRNYD 405
            K L + D
Sbjct: 1265 KVLDDMD 1271



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 60/346 (17%), Positives = 145/346 (41%), Gaps = 15/346 (4%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
            E L++  + LQ ++++   K +E      ++      + L E L   R   +       +
Sbjct: 839  EELERRVAQLQRQIEDL--KGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRA 896

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E+ L  A+  ++   ++ K    + +   ++ + L +L N +  ER H    +++L  Q
Sbjct: 897  LENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKL--Q 954

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
             E A+ V  SR S  + + +  + K   ++  + +A                +L + + +
Sbjct: 955  KEMADIVEASRTSTLELQNQLDEYK---EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011

Query: 275  S-IRLVDMERRRCLEYVPCKENEPTDRET--EIWKELQMTRGALLRSEEELRQSRAEKDS 331
              +RL++ E R   +Y   ++   T R+   +  K+L+    A    +++  +   + + 
Sbjct: 1012 DEMRLMEEELR---DYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMED 1068

Query: 332  FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
             ++ L    + E   S  D ++  +    +++ +L+  + ++R   + +E      E Q 
Sbjct: 1069 KVSQLEMELEEERNNS--DLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQN 1126

Query: 392  AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
              L+  +  L      SK+    +++  I +L  ++E+  R+R  L
Sbjct: 1127 KDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANL 1172



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 44/208 (21%), Positives = 94/208 (45%), Gaps = 13/208 (6%)

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
           QL+    ++I+      R  LE +  + NE  +  + + + L+ + G L ++ EEL Q +
Sbjct: 631 QLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVK 690

Query: 327 AEKDSFLNSLSRIAQGEGTESFQD-KMATELLDRE-----QKIVKLQQTIDEQRENEKSM 380
            E++     + R  Q + +E   +   A    DRE     +++++ +Q + +    ++  
Sbjct: 691 MEREQHQTEI-RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQ 749

Query: 381 EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLS-RERTALIT 439
           E  + + E +L AL+  +K     +  S D    +L+ E  D  LQ    S  E T  + 
Sbjct: 750 EDLLRKRERELTALKGALKE----EVSSHDQEMDKLK-EQYDAELQALRESVEEATKNVE 804

Query: 440 AAASRALMLERHERAADLFARMVRARKD 467
             ASR+   E+ +   ++  ++++   +
Sbjct: 805 VLASRSNTSEQDQAGTEMRVKLLQEENE 832



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 8/139 (5%)

Query: 86   DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
            DR  ++K     Q E+ + Q +++   ++ N +     +       + L  EL +ERAAR
Sbjct: 1058 DRSRLVK-----QMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAAR 1112

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHA 204
            + L+    S E   +  ++RI  LE   + +K    +  +    + +L +RL + ER  A
Sbjct: 1113 QDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEAR--IAELEDRLESEERDRA 1170

Query: 205  TVKVKELREQAETAEQVAQ 223
             +++   R + +  E V Q
Sbjct: 1171 NLQLSNRRLERKVKELVMQ 1189


>BC000099-1|AAH00099.4|  655|Homo sapiens RRBP1 protein protein.
          Length = 655

 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 77/322 (23%), Positives = 143/322 (44%), Gaps = 29/322 (9%)

Query: 93  KIERLQKENSILQHKVDE-TSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEV 151
           ++ RLQ+ENSIL+  +++ TS+ E+++         +     L +ELSK         E 
Sbjct: 39  QLARLQQENSILRDALNQATSQVESKQ---------NAELAKLRQELSKVSKELVEKSEA 89

Query: 152 VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
           V   E   +   A+ A  E+Q+   +A     ++  + L++ ++ ++ E  H       L
Sbjct: 90  VRQDEQQRKALEAKAAAFEKQVLQLQASH---RESEEALQKRLDEVSRELCHTQSSHASL 146

Query: 212 REQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSF 271
           R  AE A++  Q +++E  ++ +  +A+V    +SK                   QL   
Sbjct: 147 RADAEKAQE-QQQQMAELHSKLQSSEAEV----RSKCEELSGLHGQLQEARAENSQLTE- 200

Query: 272 RDRSIR-LVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
           R RSI  L++  + R  + V   + E   ++T + KEL+     L +   ELR++  E+ 
Sbjct: 201 RIRSIEALLEAGQARDAQDVQASQAEADQQQTRL-KELESQVSGLEKEAIELREA-VEQQ 258

Query: 331 SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
              N+  R    +  E+    +AT     ++K+  L Q   E+ E +  + +  T  E  
Sbjct: 259 KVKNNDLREKNWKAMEA----LATAEQACKEKLHSLTQA-KEESEKQLCLIEAQTM-EAL 312

Query: 391 LAAL-RLEVKRLRNYDCYSKDV 411
           LA L  L V   +NY  + +D+
Sbjct: 313 LALLPELSVLAQQNYTEWLQDL 334


>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
          Length = 1302

 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 59/275 (21%), Positives = 114/275 (41%), Gaps = 11/275 (4%)

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE---LREQAETAEQV 221
            R+A L+RQ++D K +   AK+  K  E  + +L     HA  + KE    R   E   + 
Sbjct: 844  RVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEA 903

Query: 222  AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
            AQ  +S+     + L  K+ E+ + K                    ++  +     +V+ 
Sbjct: 904  AQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEA 963

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
             R   LE     +N+  + + +  +EL   +  L     E  +SR       + + R+ +
Sbjct: 964  SRTSTLEL----QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM-RLME 1018

Query: 342  GE--GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             E    +  QD+  T+    EQ +  L+  ++ +   +    + + Q E++++ L +E++
Sbjct: 1019 EELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELE 1078

Query: 400  RLR-NYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
              R N D  S+ +S    Q E L   L  E  +R+
Sbjct: 1079 EERNNSDLLSERISRSREQMEQLRNELLQERAARQ 1113



 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 68/307 (22%), Positives = 124/307 (40%), Gaps = 11/307 (3%)

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA--LKEVVASAESMLRV 161
            LQ+++DE  +K   E      Q      +     L+  +   E   ++E +   +     
Sbjct: 971  LQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDE 1030

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET-AEQ 220
            A  +   LE+ LKD + E E       D  +LV ++  + S   ++++E R  ++  +E+
Sbjct: 1031 ALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSER 1090

Query: 221  VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
            +++SR   ++ R E LQ + A Q+                      +  S+R     LV 
Sbjct: 1091 ISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE-GSYRSSKEGLVV 1149

Query: 281  MERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEEL-RQSRAEKDSFLNSLSRI 339
                R  E     E+E  DR       LQ++   L R  +EL  Q   E  S  +   ++
Sbjct: 1150 QMEARIAELEDRLESEERDRAN-----LQLSNRRLERKVKELVMQVDDEHLSLTDQKDQL 1204

Query: 340  AQGEGTESFQDKMATELLDR-EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +        Q + A E +DR E    KLQ+ ++EQ +  + ++  +   +  L   +L  
Sbjct: 1205 SLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPS 1264

Query: 399  KRLRNYD 405
            K L + D
Sbjct: 1265 KVLDDMD 1271



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 60/346 (17%), Positives = 145/346 (41%), Gaps = 15/346 (4%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
            E L++  + LQ ++++   K +E      ++      + L E L   R   +       +
Sbjct: 839  EELERRVAQLQRQIEDL--KGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRA 896

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E+ L  A+  ++   ++ K    + +   ++ + L +L N +  ER H    +++L  Q
Sbjct: 897  LENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKL--Q 954

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
             E A+ V  SR S  + + +  + K   ++  + +A                +L + + +
Sbjct: 955  KEMADIVEASRTSTLELQNQLDEYK---EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011

Query: 275  S-IRLVDMERRRCLEYVPCKENEPTDRET--EIWKELQMTRGALLRSEEELRQSRAEKDS 331
              +RL++ E R   +Y   ++   T R+   +  K+L+    A    +++  +   + + 
Sbjct: 1012 DEMRLMEEELR---DYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMED 1068

Query: 332  FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
             ++ L    + E   S  D ++  +    +++ +L+  + ++R   + +E      E Q 
Sbjct: 1069 KVSQLEMELEEERNNS--DLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQN 1126

Query: 392  AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
              L+  +  L      SK+    +++  I +L  ++E+  R+R  L
Sbjct: 1127 KDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANL 1172



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 44/208 (21%), Positives = 94/208 (45%), Gaps = 13/208 (6%)

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
           QL+    ++I+      R  LE +  + NE  +  + + + L+ + G L ++ EEL Q +
Sbjct: 631 QLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVK 690

Query: 327 AEKDSFLNSLSRIAQGEGTESFQD-KMATELLDRE-----QKIVKLQQTIDEQRENEKSM 380
            E++     + R  Q + +E   +   A    DRE     +++++ +Q + +    ++  
Sbjct: 691 MEREQHQTEI-RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQ 749

Query: 381 EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLS-RERTALIT 439
           E  + + E +L AL+  +K     +  S D    +L+ E  D  LQ    S  E T  + 
Sbjct: 750 EDLLRKRERELTALKGALKE----EVSSHDQEMDKLK-EQYDAELQALRESVEEATKNVE 804

Query: 440 AAASRALMLERHERAADLFARMVRARKD 467
             ASR+   E+ +   ++  ++++   +
Sbjct: 805 VLASRSNTSEQDQAGTEMRVKLLQEENE 832



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 8/139 (5%)

Query: 86   DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
            DR  ++K     Q E+ + Q +++   ++ N +     +       + L  EL +ERAAR
Sbjct: 1058 DRSRLVK-----QMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAAR 1112

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHA 204
            + L+    S E   +  ++RI  LE   + +K    +  +    + +L +RL + ER  A
Sbjct: 1113 QDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEAR--IAELEDRLESEERDRA 1170

Query: 205  TVKVKELREQAETAEQVAQ 223
             +++   R + +  E V Q
Sbjct: 1171 NLQLSNRRLERKVKELVMQ 1189


>AK027863-1|BAB55415.1|  612|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14957 fis, clone PLACE4000009, weakly similar to
           MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
          Length = 612

 Score = 51.2 bits (117), Expect = 8e-06
 Identities = 68/307 (22%), Positives = 123/307 (40%), Gaps = 11/307 (3%)

Query: 104 LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELS--KERAAREALKEVVASAESMLRV 161
           LQ+++DE  +K   E      Q      +     L+  K +     ++E +   +     
Sbjct: 281 LQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDE 340

Query: 162 ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET-AEQ 220
           A  +   LE+ LKD + E E       D  +LV ++  + S   ++++E R  ++   E+
Sbjct: 341 ALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLTER 400

Query: 221 VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
           +++SR   ++ R E LQ + A Q+                      +  S+R     LV 
Sbjct: 401 ISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLE-GSYRSSKEGLVV 459

Query: 281 MERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEEL-RQSRAEKDSFLNSLSRI 339
               R  E     E+E  DR       LQ++   L R  +EL  Q   E  S  +   ++
Sbjct: 460 QMEARIAELEDRLESEERDRAN-----LQLSNRRLERKVKELVMQVDDEHLSLTDQKDQL 514

Query: 340 AQGEGTESFQDKMATELLDR-EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
           +        Q + A E +DR E    KLQ+ ++EQ +  + ++  +   +  L   +L  
Sbjct: 515 SLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPS 574

Query: 399 KRLRNYD 405
           K L + D
Sbjct: 575 KVLDDMD 581



 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 57/275 (20%), Positives = 113/275 (41%), Gaps = 11/275 (4%)

Query: 165 RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE---LREQAETAEQV 221
           R+A L+RQ++D K +   AK+  K  E  + +L     H   + KE    R   E   + 
Sbjct: 154 RVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHVRKEEKEAVSARRALENELEA 213

Query: 222 AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
           AQ  +S+     + L  K+ E+ + K                    ++  +     +V+ 
Sbjct: 214 AQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEA 273

Query: 282 ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
            R   LE     +N+  + + +  +EL   +  L     E  +SR       + + R+ +
Sbjct: 274 SRTSTLEL----QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGM-RLME 328

Query: 342 GE--GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
            E    +  QD+  T+    EQ +  L+  ++ +   +    + + Q E++++ L +E++
Sbjct: 329 EELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELE 388

Query: 400 RLR-NYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
             R N D  ++ +S    Q E L   L  E  +R+
Sbjct: 389 EERNNSDLLTERISRSREQMEQLRNELLQERAARQ 423



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 64/347 (18%), Positives = 147/347 (42%), Gaps = 17/347 (4%)

Query: 95  ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
           E L++  + LQ ++++   K +E      ++      + L E L   R   +       +
Sbjct: 149 EELERRVAQLQRQIEDL--KGDEAKAKETLKKYEGEIRQLEEALVHVRKEEKEAVSARRA 206

Query: 155 AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
            E+ L  A+  ++   ++ K    + +   ++ + L +L N +  ER H    +++L  Q
Sbjct: 207 LENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKL--Q 264

Query: 215 AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
            E A+ V  SR S  + + +  + K   ++  + +A                +L + + +
Sbjct: 265 KEMADIVEASRTSTLELQNQLDEYK---EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 321

Query: 275 S-IRLVDMERRRCLEYVPCKENEPTDRET--EIWKELQMTRGALLRSEEELRQSRAEKDS 331
             +RL++ E R   +Y   ++   T R+   +  K+L+    A    +++  +SR  K  
Sbjct: 322 DGMRLMEEELR---DYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDD--RSRLVKQ- 375

Query: 332 FLNSLSRIAQGEGTESFQDKMATELLDRE-QKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
             + +S++      E     + TE + R  +++ +L+  + ++R   + +E      E Q
Sbjct: 376 MEDKVSQLEMELEEERNNSDLLTERISRSREQMEQLRNELLQERAARQDLECDKISLERQ 435

Query: 391 LAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
              L+  +  L      SK+    +++  I +L  ++E+  R+R  L
Sbjct: 436 NKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANL 482



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 8/139 (5%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           DR  ++K     Q E+ + Q +++   ++ N +     +       + L  EL +ERAAR
Sbjct: 368 DRSRLVK-----QMEDKVSQLEMELEEERNNSDLLTERISRSREQMEQLRNELLQERAAR 422

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHA 204
           + L+    S E   +  ++RI  LE   + +K    +  +    + +L +RL + ER  A
Sbjct: 423 QDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEAR--IAELEDRLESEERDRA 480

Query: 205 TVKVKELREQAETAEQVAQ 223
            +++   R + +  E V Q
Sbjct: 481 NLQLSNRRLERKVKELVMQ 499


>Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.
          Length = 2101

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 68/317 (21%), Positives = 131/317 (41%), Gaps = 15/317 (4%)

Query: 136 EELSKERAAR--------EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKH 187
           E L KE+AA+        +   E   SA++ +  A+   A L R++++ +A  E A+++ 
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ 666

Query: 188 KDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
            + +  V  L ++      K  E    A+  +Q+ Q ++   K   +  +  + E+++  
Sbjct: 667 HEAQAQVAELELQLRSEQQKATEKERVAQEKDQL-QEQLQALKESLKVTKGSLEEEKRRA 725

Query: 248 AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKENEPTDRETEIW 305
           A A                 L     R  + ++ ER  R+ LE    +  E    ETE+ 
Sbjct: 726 ADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLLQLGEAHQAETEVL 785

Query: 306 K-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES--FQDKMATELLDREQK 362
           + EL     A   +E E  Q   E  ++ +      Q E      FQ+++ T   + E+ 
Sbjct: 786 RRELAEAMAAQHTAESECEQLVKEVAAWRDGYEDSQQEEAQYGAMFQEQLMTLKEECEKA 845

Query: 363 IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILD 422
             +LQ+  ++    E   E  +++ +N+LA L   + R        K+V   +L  ++  
Sbjct: 846 RQELQEAKEKVAGIESHSELQISRQQNKLAELHANLARALQ-QVQEKEVRAQKLADDLST 904

Query: 423 LHLQVETLSRERTALIT 439
           L  ++   S+E   L T
Sbjct: 905 LQEKMAATSKEVARLET 921



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 65/309 (21%), Positives = 132/309 (42%), Gaps = 17/309 (5%)

Query: 136  EELSKERAA-REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            E+L KE AA R+  ++          + + ++ TL+ + +  + E + AK+K   +E   
Sbjct: 804  EQLVKEVAAWRDGYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESH- 862

Query: 195  NRLAIERSHATVKVKELREQ-AETAEQVAQSRVSEQKARTEF--LQAKVAEQEKSKAVAX 251
            + L I R     K+ EL    A   +QV +  V  QK   +   LQ K+A   K  A   
Sbjct: 863  SELQISRQQN--KLAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLE 920

Query: 252  XXXXXXXXXXXXXXXQL--QSFRDRSIRLVDMERRRCLEYVPCKEN-EPTDRETE-IWKE 307
                           +L  +  R    +   +E ++  ++   +   +  +RE E +  E
Sbjct: 921  TLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNE 980

Query: 308  LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
            L+  R AL+ S+ + ++ R +++     ++R+ Q  G    Q  +A E   R +  ++LQ
Sbjct: 981  LERLRAALMESQGQQQEERGQQE---REVARLTQERGRA--QADLALEKAARAELEMRLQ 1035

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
              ++EQR    ++++ +     +      E+ +LR  +  ++     EL+  +  L  Q+
Sbjct: 1036 NALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA-AQIKELEELRQTVKQLKEQL 1094

Query: 428  ETLSRERTA 436
                +E  +
Sbjct: 1095 AKKEKEHAS 1103



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 82/406 (20%), Positives = 159/406 (39%), Gaps = 31/406 (7%)

Query: 67  ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
           E+L  +++ +L+  +    ++  M +KI +L +EN  L  K+ E +         H  Q 
Sbjct: 286 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFAS--------HLQQL 337

Query: 127 GSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKK 186
                  LNE   +   A +   E  A  E  L  A      LE + +  + +     + 
Sbjct: 338 ----QDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKL---SQL 390

Query: 187 HKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
            + L QL +    E+      V +L    + A  +A +  ++ +AR E L+ +  +QE  
Sbjct: 391 EEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANN-TQLQARVEMLETERGQQEAK 449

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
                                LQS    SI  +   +    +         T +   +  
Sbjct: 450 LLAERGHFEEEKQQLSSLITDLQS----SISNLSQAKEELEQASQAHGARLTAQVASLTS 505

Query: 307 ELQMTRGALLRSEEE---LRQSRAEKDSFL-NSLSRIAQ-GEGTESFQDKMATELLDREQ 361
           EL      + + ++E   L+Q   EK + L  +L +  Q  +G     +++++ L  +EQ
Sbjct: 506 ELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ 565

Query: 362 KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEIL 421
           ++ ++ +  +  R++    +Q  T  E + A+LR     L+  +   K+ +    + EIL
Sbjct: 566 QLKEVAEKQEATRQDH--AQQLATAAEEREASLRERDAALKQLEALEKEKA---AKLEIL 620

Query: 422 DLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKD 467
              LQV   +R+        A R    E   +  +L A +  AR++
Sbjct: 621 QQQLQVANEARDSAQTSVTQAQRE-KAELSRKVEELQACVETARQE 665



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 78/400 (19%), Positives = 154/400 (38%), Gaps = 32/400 (8%)

Query: 97  LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAE 156
           L+++N ILQ K+ +  +  ++     P + G     VL  E  K+ AA       +A+  
Sbjct: 376 LEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAA------TLAANN 429

Query: 157 SMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAE 216
           + L+   AR+  LE +    +A+    +   ++ +Q ++ L  +   +   + + +E+ E
Sbjct: 430 TQLQ---ARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELE 486

Query: 217 TAEQVAQSRVSEQKA----RTEFLQAKVAEQEKS----KAVAXXXXXXXXXXXXXXXXQL 268
            A Q   +R++ Q A        L A + +Q++     K  A                  
Sbjct: 487 QASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQAS 546

Query: 269 QSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIW--------KELQM-TRGALLRSE 319
           Q  R +  +L    +++  +     E +   R+            +E  +  R A L+  
Sbjct: 547 QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL 606

Query: 320 EELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA---TELLDREQKIVKLQQTIDEQREN 376
           E L + +A K   L    ++A  E  +S Q  +     E  +  +K+ +LQ  ++  R+ 
Sbjct: 607 EALEKEKAAKLEILQQQLQVA-NEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665

Query: 377 EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE-RT 435
           +   +  + + E QL + + +    +      KD    +LQ     L +   +L  E R 
Sbjct: 666 QHEAQAQVAELELQLRSEQQKATE-KERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR 724

Query: 436 ALITAAASRALMLERHERAADLFARMVRARKDLAALLDGR 475
           A       +  + E       L  +  R RK+L     GR
Sbjct: 725 AADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGR 764



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 94/417 (22%), Positives = 163/417 (39%), Gaps = 52/417 (12%)

Query: 86   DRDTMIKKIERLQKENSILQ---HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKER 142
            D  T+ +K+    KE + L+    K  E  +  + E    P ++G    + L E+  ++ 
Sbjct: 901  DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF 960

Query: 143  AAREA-LKEVVASAESM-LRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
             + +A L+ +   AE M   + R R A +E Q +         +++    E+ V RL  E
Sbjct: 961  CSTQAALQAMEREAEQMGNELERLRAALMESQGQQ--------QEERGQQEREVARLTQE 1012

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXX 260
            R  A   +   +      E   Q+ ++EQ+     LQ  +A     K             
Sbjct: 1013 RGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGL 1072

Query: 261  XXXXXXQLQSFRDRSIRLVDMERRRCLEYVP--------CKENEPTDRETEIWK------ 306
                  +L+  R    +L +   ++  E+              EPT  + E  +      
Sbjct: 1073 EAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKL 1132

Query: 307  -----ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
                 + Q    +L RS E  R SRAE+DS L +L    QG+      ++ A EL   + 
Sbjct: 1133 EQQCQKQQEQADSLERSLEAERASRAERDSALETL----QGQ-----LEEKAQELGHSQS 1183

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEIL 421
             +   Q+ +   R   +   +   +++ Q+A  R E +R  +       +S  E +  IL
Sbjct: 1184 ALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSL------ISSLEEEVSIL 1237

Query: 422  DLH-LQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDL--AALLDGR 475
            +   L+ E  S+E   L+ A + ++  LE  E  A    R      +L  AALL GR
Sbjct: 1238 NRQVLEKEGESKELKRLVMAESEKSQKLE--ESCACCRQRQPATVPELQNAALLCGR 1292



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 60/272 (22%), Positives = 113/272 (41%), Gaps = 27/272 (9%)

Query: 134  LNEELSKERAAREALKEVVASAESM--LRVARARI------ATLERQLKDTKAEFEIAKK 185
            L EE  K R   +  KE VA  ES   L+++R +       A L R L+  + +   A+K
Sbjct: 838  LKEECEKARQELQEAKEKVAGIESHSELQISRQQNKLAELHANLARALQQVQEKEVRAQK 897

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEK 245
               DL  L  ++A   S    +++ L  +A   ++ A   + ++ AR    Q +  E+++
Sbjct: 898  LADDLSTLQEKMAAT-SKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQ 956

Query: 246  SKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIW 305
             +                   + +   +   RL    R   +E    ++ E   +E E+ 
Sbjct: 957  GRQFCSTQAALQAMER-----EAEQMGNELERL----RAALMESQGQQQEERGQQEREVA 1007

Query: 306  KELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDRE--- 360
            + L   RG   R++ +L   +A +      L      +  E  + Q+ +A  L ++E   
Sbjct: 1008 R-LTQERG---RAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKD 1063

Query: 361  QKIVKLQQTIDEQRENEKSMEQTMTQYENQLA 392
            Q++ KL+     Q +  + + QT+ Q + QLA
Sbjct: 1064 QELAKLRGLEAAQIKELEELRQTVKQLKEQLA 1095



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 30/160 (18%), Positives = 71/160 (44%), Gaps = 3/160 (1%)

Query: 90   MIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            ++++ +R Q+E   L  +V+E SKK  +      VQ             S++ A R   +
Sbjct: 1519 VLEERQRFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQR--FQ 1576

Query: 150  EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDL-EQLVNRLAIERSHATVKV 208
              +   ++ L          + Q++  K  ++  K+++++L EQL +   +++ +  ++ 
Sbjct: 1577 AQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRA 1636

Query: 209  KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
            +  R   E  +   +++ +EQ  R    Q +  E + + A
Sbjct: 1637 EAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHA 1676


>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
          Length = 3259

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 68/342 (19%), Positives = 156/342 (45%), Gaps = 23/342 (6%)

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVAR 163
            LQ KV +T + EN+E     ++   + Y     EL+K  +  ++LK+ +    + L   +
Sbjct: 2274 LQQKVCDTLQGENKEL-LSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCK 2332

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLE-------QLVNRLAIERSHATVKVKELREQAE 216
             +   LE  ++  +A+ + +K  ++ LE       +L +RL  E +    K+  L    E
Sbjct: 2333 EQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKE 2392

Query: 217  TAEQVAQSRVSEQKAR-TEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRS 275
             A QVA + + +Q  +  + L+  ++++E+   V                  L++ +  +
Sbjct: 2393 EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEN 2452

Query: 276  IRLVDMERRRCLEYVPCKENEPTDRETEI--WKELQMTRGALLRSEEELRQSRAEKDSFL 333
            I+    ++ +   +V    +   DR+  +  +++L+    +++  +++L Q  A +++ L
Sbjct: 2453 IQ----QKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKL 2508

Query: 334  NSLSRIAQG--EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME-QTMTQYENQ 390
                R  +   +   S   K+  EL+   + + ++    D Q++    ++ Q   + EN+
Sbjct: 2509 KEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENK 2568

Query: 391  LAALRLEVKRLRNYDCYSKDV--SYPELQTEILDLHLQVETL 430
             A L    ++L+  +  ++D+  S+  LQ E  DL  ++E+L
Sbjct: 2569 YAKLE---EKLKESEEANEDLRRSFNALQEEKQDLSKEIESL 2607



 Score = 48.0 bits (109), Expect = 7e-05
 Identities = 78/373 (20%), Positives = 150/373 (40%), Gaps = 37/373 (9%)

Query: 98  QKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK----EVVA 153
           Q E  + +H    T ++   E   H +Q        L  +L++ +A + A      E   
Sbjct: 127 QSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFV 186

Query: 154 SAESMLRVARARIATLERQLKDTKAE-------------FEIAKKKHKD-LEQLVNRLAI 199
             +  L+     I+TL+ QL  T+AE             FE   + H+D L QLV +  +
Sbjct: 187 MMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADV 246

Query: 200 ERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXX 259
           E    T   ++LR      E+  +S V   +   + LQ ++   E+   +          
Sbjct: 247 E----TEMQQKLRVLQRKLEEHEESLVGRAQV-VDLLQQELTAAEQRNQILSQQLQQMEA 301

Query: 260 XXXXXXXQLQSFRDRS-IRLVDME---RRRCLEYVPCKEN-----EPTDRETEIWKELQM 310
                   +++ R+ S I L  ME     R L +   +E      E  ++  +   EL+ 
Sbjct: 302 EHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELES 361

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSLSRIAQG--EGTESFQDKMATELLDREQKIVKLQQ 368
              AL   E++ +    EK S + SL +  Q      ++ +D+ +  L D+ ++ V+  Q
Sbjct: 362 RYSAL---EQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQ 418

Query: 369 TIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVE 428
           TI +  +  +   + ++Q+ N+L   + E     ++     + +    +  I  L  +V 
Sbjct: 419 TIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVV 478

Query: 429 TLSRERTALITAA 441
            L  E+ AL+ ++
Sbjct: 479 ELENEKGALLLSS 491



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 51/227 (22%), Positives = 99/227 (43%), Gaps = 19/227 (8%)

Query: 185 KKHKDLEQLVNRL---AIERSHATVKVKELREQAETAEQVAQ-SRVSEQKARTEFLQAKV 240
           K+  +L QL+      A   S A   + E R+Q     QV + S V+E +A+ + L+  +
Sbjct: 716 KEISNLNQLIEEFKKNADNNSSAFTALSEERDQL--LSQVKELSMVTELRAQVKQLEMNL 773

Query: 241 AEQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTD 299
           AE E+ + +                  L    + + +++  ++    L+ V  + +E + 
Sbjct: 774 AEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNE--LDDVQLQFSEQST 831

Query: 300 RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR 359
               +  +LQ     +L   E +R   ++ +    +LS+       E    KM   LL++
Sbjct: 832 LIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQ------KELEITKMDQLLLEK 885

Query: 360 EQKIVKLQQTIDEQ----RENEKSMEQTMTQYENQLAALRLEVKRLR 402
           ++ +  LQQTI+E+     E   SM + M Q   +  +L +E+K L+
Sbjct: 886 KRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLK 932



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 75/366 (20%), Positives = 157/366 (42%), Gaps = 29/366 (7%)

Query: 88   DTMIKKIERLQKENSILQHKVDETSKKENEEPPC-HPVQSGSYNYQVLNEELSKERAARE 146
            D + ++I  L++E    Q   + +   ENE+      + +     ++L EE++K     +
Sbjct: 1843 DQLKERIAGLEEEK---QKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQ 1899

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKH-KDLE--QLVNRLAIERSH 203
             ++E ++    +   A      LE +L +  AE   +   + +D+   Q+ N L +E   
Sbjct: 1900 QIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNEL-LESEM 1958

Query: 204  ATVKVKELREQAETAEQVAQSRVS-EQKARTEFLQA-KVAEQEKSKAVAXXXXXXXXXXX 261
              +K K + E  E  +Q+ + +   E + R E+L+  + A++E                 
Sbjct: 1959 KNLK-KCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEK 2017

Query: 262  XXXXXQLQSFRDR-SIRLVDMERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE 319
                 QLQ    R   ++  +ER  + LE+V          +TE  K+L++T+  L ++ 
Sbjct: 2018 QQEVKQLQKDCIRYQEKISALERTVKALEFV----------QTESQKDLEITKENLAQAV 2067

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD--KMATELLDREQKIVKLQQTIDEQRENE 377
            E  ++++AE  SF   L    Q E      D  K+  EL   ++ +    +  DE  + E
Sbjct: 2068 EHRKKAQAELASF-KVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDE--DLE 2124

Query: 378  KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            + +EQ   ++  +   ++ ++  LR    + ++ +  E+Q  +     +V+ L     + 
Sbjct: 2125 RRLEQAEEKHLKEKKNMQEKLDALRREKVHLEE-TIGEIQVTLNKKDKEVQQLQENLDST 2183

Query: 438  ITAAAS 443
            +T  A+
Sbjct: 2184 VTQLAA 2189



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 34/160 (21%), Positives = 74/160 (46%), Gaps = 6/160 (3%)

Query: 86   DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
            D++ ++K+IE L K + I +    +   KE ++     +QS    Y+ ++ E  + +   
Sbjct: 1582 DKEKLVKEIESL-KSSKIAESTEWQEKHKELQKEYEILLQS----YENVSNEAERIQHVV 1636

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
            EA+++        LR   A     E+QL++ + E E  K+K +   +   +  +E     
Sbjct: 1637 EAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEEN 1696

Query: 206  VKVK-ELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQE 244
             +++ E+    +TA++  ++ +S   +  E L+    E E
Sbjct: 1697 DRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYE 1736



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 60/298 (20%), Positives = 125/298 (41%), Gaps = 30/298 (10%)

Query: 132 QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE-IAKKKHKDL 190
           Q+L+++L +  A    L+  V   E+    ++  +  +E ++ + K  F  + ++ H  L
Sbjct: 290 QILSQQLQQMEAEHNTLRNTV---ETEREESKILLEKMELEVAERKLSFHNLQEEMHHLL 346

Query: 191 EQLVN----RLAIERSHATVKVKELREQAETAEQVA--QSRVSEQKARTEFLQ---AKVA 241
           EQ       +  +E  ++ ++ K   E  E    +   Q    E ++  + L+   +K+ 
Sbjct: 347 EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLL 406

Query: 242 EQEKSKAV-AXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDR 300
           + +  +AV +                ++  F +R + L   E      + P   NE T  
Sbjct: 407 QDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNR-LPLQQHETASQTSF-PDVYNEGTQA 464

Query: 301 ETE-----IWK---ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQDK 351
            TE     + K   EL+  +GALL S  EL + +AE +   + ++ + AQ    E+ ++ 
Sbjct: 465 VTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREV 524

Query: 352 MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSK 409
               ++D   K     ++   +   +  +E T +Q   +L+ L LE+K  +    + K
Sbjct: 525 SEISIVDIANK-----RSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLK 577



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 40/212 (18%), Positives = 88/212 (41%), Gaps = 8/212 (3%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWL------DRDTMIKKIERLQ 98
            + + +E     ER+  + + + E  +A     LEI K+  L      D +T+ + IE   
Sbjct: 841  QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKD 900

Query: 99   KENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESM 158
            ++ + +   + E   + NEE     V+  +   Q LN     E A +E ++E    +  +
Sbjct: 901  QQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQ-LNLLSRAEEAKKEQVEEDNEVSSGL 959

Query: 159  LRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETA 218
             +         +   ++ + EF++ KK+++  ++ +    I R     +V  L E+    
Sbjct: 960  KQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANL 1019

Query: 219  EQVAQSRVS-EQKARTEFLQAKVAEQEKSKAV 249
            +  ++  +   +  R E  + K  ++   K V
Sbjct: 1020 KDESKKEIPLSETERGEVEEDKENKEYSEKCV 1051


>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
          Length = 3225

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 68/342 (19%), Positives = 156/342 (45%), Gaps = 23/342 (6%)

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVAR 163
            LQ KV +T + EN+E     ++   + Y     EL+K  +  ++LK+ +    + L   +
Sbjct: 2240 LQQKVCDTLQGENKEL-LSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCK 2298

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLE-------QLVNRLAIERSHATVKVKELREQAE 216
             +   LE  ++  +A+ + +K  ++ LE       +L +RL  E +    K+  L    E
Sbjct: 2299 EQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKE 2358

Query: 217  TAEQVAQSRVSEQKAR-TEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRS 275
             A QVA + + +Q  +  + L+  ++++E+   V                  L++ +  +
Sbjct: 2359 EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEN 2418

Query: 276  IRLVDMERRRCLEYVPCKENEPTDRETEI--WKELQMTRGALLRSEEELRQSRAEKDSFL 333
            I+    ++ +   +V    +   DR+  +  +++L+    +++  +++L Q  A +++ L
Sbjct: 2419 IQ----QKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKL 2474

Query: 334  NSLSRIAQG--EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME-QTMTQYENQ 390
                R  +   +   S   K+  EL+   + + ++    D Q++    ++ Q   + EN+
Sbjct: 2475 KEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENK 2534

Query: 391  LAALRLEVKRLRNYDCYSKDV--SYPELQTEILDLHLQVETL 430
             A L    ++L+  +  ++D+  S+  LQ E  DL  ++E+L
Sbjct: 2535 YAKLE---EKLKESEEANEDLRRSFNALQEEKQDLSKEIESL 2573



 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 70/369 (18%), Positives = 160/369 (43%), Gaps = 26/369 (7%)

Query: 86  DRDTMIKKIE-RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           + +  I+KI+ +LQ++  ++     + ++ + E+P     +   +   V+ ++  +E+  
Sbjct: 102 EEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEF---VMMKQQLQEK-- 156

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD-LEQLVNRLAIERSH 203
            E +  + A          A+++++++ +++  A FE   + H+D L QLV +  +E   
Sbjct: 157 EEFISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVE--- 213

Query: 204 ATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            T   ++LR      E+  +S V   +   + LQ ++   E+   +              
Sbjct: 214 -TEMQQKLRVLQRKLEEHEESLVGRAQV-VDLLQQELTAAEQRNQILSQQLQQMEAEHNT 271

Query: 264 XXXQLQSFRDRS-IRLVDME---RRRCLEYVPCKEN-----EPTDRETEIWKELQMTRGA 314
               +++ R+ S I L  ME     R L +   +E      E  ++  +   EL+    A
Sbjct: 272 LRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSA 331

Query: 315 LLRSEEELRQSRAEKDSFLNSLSRIAQG--EGTESFQDKMATELLDREQKIVKLQQTIDE 372
           L   E++ +    EK S + SL +  Q      ++ +D+ +  L D+ ++ V+  QTI +
Sbjct: 332 L---EQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQ 388

Query: 373 QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
             +  +   + ++Q+ N+L   + E     ++     + +    +  I  L  +V  L  
Sbjct: 389 LEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELEN 448

Query: 433 ERTALITAA 441
           E+ AL+ ++
Sbjct: 449 EKGALLLSS 457



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 51/227 (22%), Positives = 99/227 (43%), Gaps = 19/227 (8%)

Query: 185 KKHKDLEQLVNRL---AIERSHATVKVKELREQAETAEQVAQ-SRVSEQKARTEFLQAKV 240
           K+  +L QL+      A   S A   + E R+Q     QV + S V+E +A+ + L+  +
Sbjct: 682 KEISNLNQLIEEFKKNADNNSSAFTALSEERDQL--LSQVKELSMVTELRAQVKQLEMNL 739

Query: 241 AEQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTD 299
           AE E+ + +                  L    + + +++  ++    L+ V  + +E + 
Sbjct: 740 AEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNE--LDDVQLQFSEQST 797

Query: 300 RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR 359
               +  +LQ     +L   E +R   ++ +    +LS+       E    KM   LL++
Sbjct: 798 LIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQ------KELEITKMDQLLLEK 851

Query: 360 EQKIVKLQQTIDEQ----RENEKSMEQTMTQYENQLAALRLEVKRLR 402
           ++ +  LQQTI+E+     E   SM + M Q   +  +L +E+K L+
Sbjct: 852 KRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLK 898



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 52/290 (17%), Positives = 119/290 (41%), Gaps = 14/290 (4%)

Query: 165 RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
           R+A  E+ + + K   +I ++K   L+Q    L  ER  A  K+K+L+  A+        
Sbjct: 14  RLAYAEQLVVELK---DIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNK 70

Query: 225 RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR 284
            + E KA+   +     + E+  +                  +LQ  ++  I  +  +  
Sbjct: 71  YIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQE-KEELISTLQAQLT 129

Query: 285 RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEG 344
           +     P + +   +    + ++LQ     +   + +L Q++AE+ + L+S+ ++ + + 
Sbjct: 130 QAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREKD 189

Query: 345 TESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNY 404
                 +  T++   E ++++L    D + E ++ +     + E    +L   V R +  
Sbjct: 190 A-----RFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESL---VGRAQVV 241

Query: 405 DCYSKDVSYPELQTEILDLHLQVETLSRE--RTALITAAASRALMLERHE 452
           D   ++++  E + +IL   LQ         R  + T      ++LE+ E
Sbjct: 242 DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKME 291



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 75/366 (20%), Positives = 157/366 (42%), Gaps = 29/366 (7%)

Query: 88   DTMIKKIERLQKENSILQHKVDETSKKENEEPPC-HPVQSGSYNYQVLNEELSKERAARE 146
            D + ++I  L++E    Q   + +   ENE+      + +     ++L EE++K     +
Sbjct: 1809 DQLKERIAGLEEEK---QKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQ 1865

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKH-KDLE--QLVNRLAIERSH 203
             ++E ++    +   A      LE +L +  AE   +   + +D+   Q+ N L +E   
Sbjct: 1866 QIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNEL-LESEM 1924

Query: 204  ATVKVKELREQAETAEQVAQSRVS-EQKARTEFLQA-KVAEQEKSKAVAXXXXXXXXXXX 261
              +K K + E  E  +Q+ + +   E + R E+L+  + A++E                 
Sbjct: 1925 KNLK-KCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEK 1983

Query: 262  XXXXXQLQSFRDR-SIRLVDMERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE 319
                 QLQ    R   ++  +ER  + LE+V          +TE  K+L++T+  L ++ 
Sbjct: 1984 QQEVKQLQKDCIRYQEKISALERTVKALEFV----------QTESQKDLEITKENLAQAV 2033

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD--KMATELLDREQKIVKLQQTIDEQRENE 377
            E  ++++AE  SF   L    Q E      D  K+  EL   ++ +    +  DE  + E
Sbjct: 2034 EHRKKAQAELASF-KVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDE--DLE 2090

Query: 378  KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            + +EQ   ++  +   ++ ++  LR    + ++ +  E+Q  +     +V+ L     + 
Sbjct: 2091 RRLEQAEEKHLKEKKNMQEKLDALRREKVHLEE-TIGEIQVTLNKKDKEVQQLQENLDST 2149

Query: 438  ITAAAS 443
            +T  A+
Sbjct: 2150 VTQLAA 2155



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 34/160 (21%), Positives = 74/160 (46%), Gaps = 6/160 (3%)

Query: 86   DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
            D++ ++K+IE L K + I +    +   KE ++     +QS    Y+ ++ E  + +   
Sbjct: 1548 DKEKLVKEIESL-KSSKIAESTEWQEKHKELQKEYEILLQS----YENVSNEAERIQHVV 1602

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
            EA+++        LR   A     E+QL++ + E E  K+K +   +   +  +E     
Sbjct: 1603 EAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEEN 1662

Query: 206  VKVK-ELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQE 244
             +++ E+    +TA++  ++ +S   +  E L+    E E
Sbjct: 1663 DRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYE 1702



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 60/298 (20%), Positives = 125/298 (41%), Gaps = 30/298 (10%)

Query: 132 QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE-IAKKKHKDL 190
           Q+L+++L +  A    L+  V   E+    ++  +  +E ++ + K  F  + ++ H  L
Sbjct: 256 QILSQQLQQMEAEHNTLRNTV---ETEREESKILLEKMELEVAERKLSFHNLQEEMHHLL 312

Query: 191 EQLVN----RLAIERSHATVKVKELREQAETAEQVA--QSRVSEQKARTEFLQ---AKVA 241
           EQ       +  +E  ++ ++ K   E  E    +   Q    E ++  + L+   +K+ 
Sbjct: 313 EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLL 372

Query: 242 EQEKSKAV-AXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDR 300
           + +  +AV +                ++  F +R + L   E      + P   NE T  
Sbjct: 373 QDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNR-LPLQQHETASQTSF-PDVYNEGTQA 430

Query: 301 ETE-----IWK---ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQDK 351
            TE     + K   EL+  +GALL S  EL + +AE +   + ++ + AQ    E+ ++ 
Sbjct: 431 VTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREV 490

Query: 352 MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSK 409
               ++D   K     ++   +   +  +E T +Q   +L+ L LE+K  +    + K
Sbjct: 491 SEISIVDIANK-----RSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLK 543



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 40/212 (18%), Positives = 88/212 (41%), Gaps = 8/212 (3%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWL------DRDTMIKKIERLQ 98
            + + +E     ER+  + + + E  +A     LEI K+  L      D +T+ + IE   
Sbjct: 807  QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKD 866

Query: 99   KENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESM 158
            ++ + +   + E   + NEE     V+  +   Q LN     E A +E ++E    +  +
Sbjct: 867  QQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQ-LNLLSRAEEAKKEQVEEDNEVSSGL 925

Query: 159  LRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETA 218
             +         +   ++ + EF++ KK+++  ++ +    I R     +V  L E+    
Sbjct: 926  KQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANL 985

Query: 219  EQVAQSRVS-EQKARTEFLQAKVAEQEKSKAV 249
            +  ++  +   +  R E  + K  ++   K V
Sbjct: 986  KDESKKEIPLSETERGEVEEDKENKEYSEKCV 1017


>BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet
           coiled-coil, rootletin protein.
          Length = 1898

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 74/371 (19%), Positives = 151/371 (40%), Gaps = 23/371 (6%)

Query: 112 SKKENEEPPCHPVQSGSYNYQVLNE---ELSKERAAREALKEVVASAESMLRVARARIAT 168
           S +    P C    + +  +  L++   ++   R   EA ++++ +    L  + +    
Sbjct: 387 SPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRA 446

Query: 169 LERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE 228
           LE QL+  + + + A + H+D ++ V RL       + +   L    + A+Q A+    E
Sbjct: 447 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQE 506

Query: 229 Q---KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR-DRSIRLVDM-ER 283
           +   +A  E L+ +    E+ +  A                QL+     RS+   ++ E 
Sbjct: 507 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 566

Query: 284 RRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
           R  L     + +     + E+ + L       +  E  + + RAE+ S  +SLS+++   
Sbjct: 567 REALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLS--- 623

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT---QYENQLAALRLEVKR 400
              +  + +A + LD  + + +L++     +  ++  EQ  T   + + +L  LRLE + 
Sbjct: 624 ---ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEV 680

Query: 401 LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFAR 460
            R        +   E   E L+   Q+ TL  ER+ L    A  +  L   E+  +   R
Sbjct: 681 AR--QGLEGSLRVAEQAQEALE--QQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR 736

Query: 461 MVRARKDLAAL 471
              A++ + AL
Sbjct: 737 --EAQRQVEAL 745



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 69/334 (20%), Positives = 145/334 (43%), Gaps = 23/334 (6%)

Query: 125  QSGSYNYQVLNEELSK-ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  S + +++ ++L + ER A+ +L+E  A+ E  L+  +       R+L+  +A+ +  
Sbjct: 841  EKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ-- 898

Query: 184  KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             +  ++ E+L+ RL  E+   + ++  L+++ +    +A+S   +Q+A +      + E 
Sbjct: 899  SQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESE--KQQALS------LKES 950

Query: 244  EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            EK+ A++                  +  RD   R  + +R           +    RE  
Sbjct: 951  EKT-ALSEKLMGTRHSLATISLEMERQKRDAQSRQ-EQDRSTVNALTSELRDLRAQREEA 1008

Query: 304  IWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQK 362
                 Q  R    R +E+ R    ++DS L     +  Q    E  +D +  ELL+ ++K
Sbjct: 1009 AAAHAQEVR----RLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 1064

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN--YDCYSKDVSYPELQTEI 420
            + + Q+  + QR+    + +++ +   +  ALR   + LR+      S+ +S  +L  E 
Sbjct: 1065 LRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISL-KLANE- 1122

Query: 421  LDLHLQVETLSRERTALITAAASRALMLERHERA 454
             D   ++  L   RTA+   A      L+  ER+
Sbjct: 1123 -DKEQKLALLEEARTAVGKEAGELRTGLQEVERS 1155



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 69/313 (22%), Positives = 127/313 (40%), Gaps = 20/313 (6%)

Query: 138  LSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEF-----EIAKKKHKD--L 190
            LS  +A     +E V  +E   R    ++ATLER L+ T++E      +I+K K  +  L
Sbjct: 1455 LSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKL 1514

Query: 191  EQLVNRL--AIERSHA-TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
            E    RL   ++ S + TVK++  R   E   Q ++  +S+++A+ + LQ +V   ++  
Sbjct: 1515 EGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQV 1574

Query: 248  AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKENEPTDRETEIW 305
            A +                 L    +    L D  R     L       N   D+   + 
Sbjct: 1575 ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQ 1634

Query: 306  KEL---QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
            K L   +  R  L    +  RQ+ +E     +SL     GE  ++ + ++A   L R + 
Sbjct: 1635 KALTACEHDRQVLQERLDAARQALSEARKQSSSL-----GEQVQTLRGEVADLELQRVEA 1689

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILD 422
              +LQQ  +  R+ ++     +   +      RL  +RL +       +   + + E   
Sbjct: 1690 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1749

Query: 423  LHLQVETLSRERT 435
            L L+ + ++  RT
Sbjct: 1750 LRLEKDRVALRRT 1762



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 76/366 (20%), Positives = 147/366 (40%), Gaps = 39/366 (10%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L + LSK  A  E+L +       ++       + L+ + +  + E  +A+++ + LE+L
Sbjct: 615 LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEEL 674

Query: 194 -----VNRLAIERS-HATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKS 246
                V R  +E S     + +E  EQ     +  +S++ EQ A+ +  L  +  E E++
Sbjct: 675 RLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 734

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIW 305
           +  A                  +     +++LV  ER  R L          ++  T + 
Sbjct: 735 RREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL----------SEEATRLR 784

Query: 306 KELQMTRGALLRSEEELRQSRAEKDSF------LNSLSRIAQGEGTESFQDKMATELLDR 359
            E +   G+L   + +L Q  A ++        L        GE     Q  +AT+    
Sbjct: 785 LEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKAS 844

Query: 360 EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR---------LEVKR--LRNYDCYS 408
             K +  Q+ +  +RE + S+ +    +E  L  L+         LE +R  L++     
Sbjct: 845 LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 904

Query: 409 KDVSYPELQTEILDLHLQVETLSRERTALITAAAS---RALMLERHERAADLFARMVRAR 465
           ++     L+ E  +L  ++  L +ER   +  A S   +AL L+  E+ A L  +++  R
Sbjct: 905 QEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA-LSEKLMGTR 963

Query: 466 KDLAAL 471
             LA +
Sbjct: 964 HSLATI 969



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 72/311 (23%), Positives = 129/311 (41%), Gaps = 30/311 (9%)

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELS-----KERAAREALKEVVASAESML 159
            + K D  S++E +    + + S   + +   EE +     + R  +E  +++    +S L
Sbjct: 975  RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCL 1034

Query: 160  RVARARIATLERQLKDTKAEF--EIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET 217
            R A   + T  R L+D +     E+ + + K  E    R  ++R  A    + L E A+ 
Sbjct: 1035 REAE-ELRTQLRLLEDARDGLRRELLEAQRKLRESQEGR-EVQRQEAGELRRSLGEGAKE 1092

Query: 218  AEQVAQS----RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
             E + +S    R + +KA +E +  K+A ++K + +A                +      
Sbjct: 1093 REALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEV 1152

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
               RL   E RR L+ +  +        T + +EL   +G L   E   ++SR E    L
Sbjct: 1153 ERSRL---EARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRET---L 1206

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEK----SMEQTMTQYEN 389
                R+ +GE +    + M  EL   ++   KLQ+   E R  E+    S+E+     + 
Sbjct: 1207 GLRQRLLKGEAS---LEVMRQELQVAQR---KLQEQEGEFRTRERRLLGSLEEARGTEKQ 1260

Query: 390  QLAALR-LEVK 399
            QL   R LE+K
Sbjct: 1261 QLDHARGLELK 1271



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 32/146 (21%), Positives = 73/146 (50%), Gaps = 8/146 (5%)

Query: 91   IKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            +  +++LQ E  +LQ ++    +   + E     V+  +   +   + ++  R   +  +
Sbjct: 1711 LNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLE--KDRVALRRTLDKVER 1768

Query: 150  EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAI-ERSHATVKV 208
            E + S E  +R++ A    L+R L  T AE E+A+ + + ++QL  ++ + E+SH+  ++
Sbjct: 1769 EKLRSHEDTVRLS-AEKGRLDRTL--TGAELELAEAQ-RQIQQLEAQVVVLEQSHSPAQL 1824

Query: 209  KELREQAETAEQVAQSRVSEQKARTE 234
            +   +Q +   Q    R+   +A+TE
Sbjct: 1825 EVDAQQQQLELQQEVERLRSAQAQTE 1850



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 81/395 (20%), Positives = 153/395 (38%), Gaps = 27/395 (6%)

Query: 86   DRDTMIKKIERLQKENSILQHKV-----DETSKKENEEPPCHPVQSGSYNYQVLNEELSK 140
            D+  + + + +L++E S LQ +      + T  +E +E             Q L   L  
Sbjct: 632  DKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRV 691

Query: 141  ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
               A+EAL++ + +        + ++A L RQL   + E E A+++ +   + + R A E
Sbjct: 692  AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 751

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKAR----TEFLQAKVAEQEKSKAVAXXXXXX 256
            +     +   L  Q   AE+  ++ +SE+  R     E L+  + E ++  A        
Sbjct: 752  KEALAKEHAGLAVQLVAAEREGRT-LSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 810

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                        ++       L  + +    + +  +E    D+E    K +Q  R A  
Sbjct: 811  LEAEGQALLLAKETLTG---ELAGLRQ----QIIATQEKASLDKELMAQKLVQAEREA-- 861

Query: 317  RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATE-LLDREQKIVKLQQTIDEQRE 375
              +  LR+ RA  +  L  L R  +    E   ++   +  L REQ+  +L   ++ ++E
Sbjct: 862  --QASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE--ELLARLEAEKE 917

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERT 435
             E S E    Q E     L  E ++ +      K+     L  +++     + T+S E  
Sbjct: 918  -ELSEEIAALQQERDEGLLLAESEKQQALSL--KESEKTALSEKLMGTRHSLATISLEME 974

Query: 436  ALITAAASRALMLERHERAADLFARMVRARKDLAA 470
                 A SR         A     R +RA+++ AA
Sbjct: 975  RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 1009



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 6/86 (6%)

Query: 306 KELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQD-KMATELLDREQK-- 362
           +E Q+ +  L R E+ L QSRAE+D      + +++ + TE  QD + A   L+ EQ+  
Sbjct: 52  EENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERD-TEHSQDLESALIRLEEEQQRS 110

Query: 363 --IVKLQQTIDEQRENEKSMEQTMTQ 386
             + ++   + EQ +   S  Q +++
Sbjct: 111 ASLAQVNAMLREQLDQAGSANQALSE 136


>BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet
           coiled-coil, rootletin protein.
          Length = 2017

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 74/371 (19%), Positives = 151/371 (40%), Gaps = 23/371 (6%)

Query: 112 SKKENEEPPCHPVQSGSYNYQVLNE---ELSKERAAREALKEVVASAESMLRVARARIAT 168
           S +    P C    + +  +  L++   ++   R   EA ++++ +    L  + +    
Sbjct: 506 SPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRA 565

Query: 169 LERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE 228
           LE QL+  + + + A + H+D ++ V RL       + +   L    + A+Q A+    E
Sbjct: 566 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQE 625

Query: 229 Q---KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR-DRSIRLVDM-ER 283
           +   +A  E L+ +    E+ +  A                QL+     RS+   ++ E 
Sbjct: 626 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 685

Query: 284 RRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
           R  L     + +     + E+ + L       +  E  + + RAE+ S  +SLS+++   
Sbjct: 686 REALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLS--- 742

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT---QYENQLAALRLEVKR 400
              +  + +A + LD  + + +L++     +  ++  EQ  T   + + +L  LRLE + 
Sbjct: 743 ---ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEV 799

Query: 401 LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFAR 460
            R        +   E   E L+   Q+ TL  ER+ L    A  +  L   E+  +   R
Sbjct: 800 AR--QGLEGSLRVAEQAQEALE--QQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR 855

Query: 461 MVRARKDLAAL 471
              A++ + AL
Sbjct: 856 --EAQRQVEAL 864



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 69/334 (20%), Positives = 145/334 (43%), Gaps = 23/334 (6%)

Query: 125  QSGSYNYQVLNEELSK-ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  S + +++ ++L + ER A+ +L+E  A+ E  L+  +       R+L+  +A+ +  
Sbjct: 960  EKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ-- 1017

Query: 184  KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             +  ++ E+L+ RL  E+   + ++  L+++ +    +A+S   +Q+A +      + E 
Sbjct: 1018 SQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESE--KQQALS------LKES 1069

Query: 244  EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            EK+ A++                  +  RD   R  + +R           +    RE  
Sbjct: 1070 EKT-ALSEKLMGTRHSLATISLEMERQKRDAQSRQ-EQDRSTVNALTSELRDLRAQREEA 1127

Query: 304  IWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQK 362
                 Q  R    R +E+ R    ++DS L     +  Q    E  +D +  ELL+ ++K
Sbjct: 1128 AAAHAQEVR----RLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 1183

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN--YDCYSKDVSYPELQTEI 420
            + + Q+  + QR+    + +++ +   +  ALR   + LR+      S+ +S  +L  E 
Sbjct: 1184 LRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISL-KLANE- 1241

Query: 421  LDLHLQVETLSRERTALITAAASRALMLERHERA 454
             D   ++  L   RTA+   A      L+  ER+
Sbjct: 1242 -DKEQKLALLEEARTAVGKEAGELRTGLQEVERS 1274



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 69/313 (22%), Positives = 127/313 (40%), Gaps = 20/313 (6%)

Query: 138  LSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEF-----EIAKKKHKD--L 190
            LS  +A     +E V  +E   R    ++ATLER L+ T++E      +I+K K  +  L
Sbjct: 1574 LSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKL 1633

Query: 191  EQLVNRL--AIERSHA-TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
            E    RL   ++ S + TVK++  R   E   Q ++  +S+++A+ + LQ +V   ++  
Sbjct: 1634 EGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQV 1693

Query: 248  AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKENEPTDRETEIW 305
            A +                 L    +    L D  R     L       N   D+   + 
Sbjct: 1694 ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQ 1753

Query: 306  KEL---QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
            K L   +  R  L    +  RQ+ +E     +SL     GE  ++ + ++A   L R + 
Sbjct: 1754 KALTACEHDRQVLQERLDAARQALSEARKQSSSL-----GEQVQTLRGEVADLELQRVEA 1808

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILD 422
              +LQQ  +  R+ ++     +   +      RL  +RL +       +   + + E   
Sbjct: 1809 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1868

Query: 423  LHLQVETLSRERT 435
            L L+ + ++  RT
Sbjct: 1869 LRLEKDRVALRRT 1881



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 76/366 (20%), Positives = 147/366 (40%), Gaps = 39/366 (10%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L + LSK  A  E+L +       ++       + L+ + +  + E  +A+++ + LE+L
Sbjct: 734  LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEEL 793

Query: 194  -----VNRLAIERS-HATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKS 246
                 V R  +E S     + +E  EQ     +  +S++ EQ A+ +  L  +  E E++
Sbjct: 794  RLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 853

Query: 247  KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIW 305
            +  A                  +     +++LV  ER  R L          ++  T + 
Sbjct: 854  RREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL----------SEEATRLR 903

Query: 306  KELQMTRGALLRSEEELRQSRAEKDSF------LNSLSRIAQGEGTESFQDKMATELLDR 359
             E +   G+L   + +L Q  A ++        L        GE     Q  +AT+    
Sbjct: 904  LEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKAS 963

Query: 360  EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR---------LEVKR--LRNYDCYS 408
              K +  Q+ +  +RE + S+ +    +E  L  L+         LE +R  L++     
Sbjct: 964  LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 1023

Query: 409  KDVSYPELQTEILDLHLQVETLSRERTALITAAAS---RALMLERHERAADLFARMVRAR 465
            ++     L+ E  +L  ++  L +ER   +  A S   +AL L+  E+ A L  +++  R
Sbjct: 1024 QEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA-LSEKLMGTR 1082

Query: 466  KDLAAL 471
              LA +
Sbjct: 1083 HSLATI 1088



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 72/311 (23%), Positives = 129/311 (41%), Gaps = 30/311 (9%)

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELS-----KERAAREALKEVVASAESML 159
            + K D  S++E +    + + S   + +   EE +     + R  +E  +++    +S L
Sbjct: 1094 RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCL 1153

Query: 160  RVARARIATLERQLKDTKAEF--EIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET 217
            R A   + T  R L+D +     E+ + + K  E    R  ++R  A    + L E A+ 
Sbjct: 1154 REAE-ELRTQLRLLEDARDGLRRELLEAQRKLRESQEGR-EVQRQEAGELRRSLGEGAKE 1211

Query: 218  AEQVAQS----RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
             E + +S    R + +KA +E +  K+A ++K + +A                +      
Sbjct: 1212 REALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEV 1271

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
               RL   E RR L+ +  +        T + +EL   +G L   E   ++SR E    L
Sbjct: 1272 ERSRL---EARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRET---L 1325

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEK----SMEQTMTQYEN 389
                R+ +GE +    + M  EL   ++   KLQ+   E R  E+    S+E+     + 
Sbjct: 1326 GLRQRLLKGEAS---LEVMRQELQVAQR---KLQEQEGEFRTRERRLLGSLEEARGTEKQ 1379

Query: 390  QLAALR-LEVK 399
            QL   R LE+K
Sbjct: 1380 QLDHARGLELK 1390



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 32/146 (21%), Positives = 73/146 (50%), Gaps = 8/146 (5%)

Query: 91   IKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            +  +++LQ E  +LQ ++    +   + E     V+  +   +   + ++  R   +  +
Sbjct: 1830 LNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLE--KDRVALRRTLDKVER 1887

Query: 150  EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAI-ERSHATVKV 208
            E + S E  +R++ A    L+R L  T AE E+A+ + + ++QL  ++ + E+SH+  ++
Sbjct: 1888 EKLRSHEDTVRLS-AEKGRLDRTL--TGAELELAEAQ-RQIQQLEAQVVVLEQSHSPAQL 1943

Query: 209  KELREQAETAEQVAQSRVSEQKARTE 234
            +   +Q +   Q    R+   +A+TE
Sbjct: 1944 EVDAQQQQLELQQEVERLRSAQAQTE 1969



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 81/395 (20%), Positives = 153/395 (38%), Gaps = 27/395 (6%)

Query: 86   DRDTMIKKIERLQKENSILQHKV-----DETSKKENEEPPCHPVQSGSYNYQVLNEELSK 140
            D+  + + + +L++E S LQ +      + T  +E +E             Q L   L  
Sbjct: 751  DKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRV 810

Query: 141  ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
               A+EAL++ + +        + ++A L RQL   + E E A+++ +   + + R A E
Sbjct: 811  AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 870

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKAR----TEFLQAKVAEQEKSKAVAXXXXXX 256
            +     +   L  Q   AE+  ++ +SE+  R     E L+  + E ++  A        
Sbjct: 871  KEALAKEHAGLAVQLVAAEREGRT-LSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 929

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                        ++       L  + +    + +  +E    D+E    K +Q  R A  
Sbjct: 930  LEAEGQALLLAKETLTG---ELAGLRQ----QIIATQEKASLDKELMAQKLVQAEREA-- 980

Query: 317  RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATE-LLDREQKIVKLQQTIDEQRE 375
              +  LR+ RA  +  L  L R  +    E   ++   +  L REQ+  +L   ++ ++E
Sbjct: 981  --QASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE--ELLARLEAEKE 1036

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERT 435
             E S E    Q E     L  E ++ +      K+     L  +++     + T+S E  
Sbjct: 1037 -ELSEEIAALQQERDEGLLLAESEKQQALSL--KESEKTALSEKLMGTRHSLATISLEME 1093

Query: 436  ALITAAASRALMLERHERAADLFARMVRARKDLAA 470
                 A SR         A     R +RA+++ AA
Sbjct: 1094 RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 1128


>BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein.
          Length = 1132

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 74/371 (19%), Positives = 151/371 (40%), Gaps = 23/371 (6%)

Query: 112 SKKENEEPPCHPVQSGSYNYQVLNE---ELSKERAAREALKEVVASAESMLRVARARIAT 168
           S +    P C    + +  +  L++   ++   R   EA ++++ +    L  + +    
Sbjct: 369 SPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRA 428

Query: 169 LERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE 228
           LE QL+  + + + A + H+D ++ V RL       + +   L    + A+Q A+    E
Sbjct: 429 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQE 488

Query: 229 Q---KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR-DRSIRLVDM-ER 283
           +   +A  E L+ +    E+ +  A                QL+     RS+   ++ E 
Sbjct: 489 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 548

Query: 284 RRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
           R  L     + +     + E+ + L       +  E  + + RAE+ S  +SLS+++   
Sbjct: 549 REALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLS--- 605

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT---QYENQLAALRLEVKR 400
              +  + +A + LD  + + +L++     +  ++  EQ  T   + + +L  LRLE + 
Sbjct: 606 ---ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEV 662

Query: 401 LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFAR 460
            R        +   E   E L+   Q+ TL  ER+ L    A  +  L   E+  +   R
Sbjct: 663 AR--QGLEGSLRVAEQAQEALE--QQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR 718

Query: 461 MVRARKDLAAL 471
              A++ + AL
Sbjct: 719 --EAQRQVEAL 727



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 56/281 (19%), Positives = 124/281 (44%), Gaps = 18/281 (6%)

Query: 125  QSGSYNYQVLNEELSK-ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  S + +++ ++L + ER A+ +L+E  A+ E  L+  +       R+L+  +A+ +  
Sbjct: 823  EKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ-- 880

Query: 184  KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             +  ++ E+L+ RL  E+   + ++  L+++ +    +A+S   +Q+A +      + E 
Sbjct: 881  SQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESE--KQQALS------LKES 932

Query: 244  EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            EK+ A++                  +  RD   R  + +R           +    RE  
Sbjct: 933  EKT-ALSEKLMGTRHSLATISLEMERQKRDAQSRQ-EQDRSTVNALTSELRDLRAQREEA 990

Query: 304  IWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQK 362
                 Q  R    R +E+ R    ++DS L     +  Q    E  +D +  ELL+ ++K
Sbjct: 991  AAAHAQEVR----RLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 1046

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
            + + Q+  + QR+    + +++ +   +  ALR   + LR+
Sbjct: 1047 LRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRS 1087



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 76/366 (20%), Positives = 147/366 (40%), Gaps = 39/366 (10%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L + LSK  A  E+L +       ++       + L+ + +  + E  +A+++ + LE+L
Sbjct: 597 LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEEL 656

Query: 194 -----VNRLAIERS-HATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKS 246
                V R  +E S     + +E  EQ     +  +S++ EQ A+ +  L  +  E E++
Sbjct: 657 RLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 716

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIW 305
           +  A                  +     +++LV  ER  R L          ++  T + 
Sbjct: 717 RREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL----------SEEATRLR 766

Query: 306 KELQMTRGALLRSEEELRQSRAEKDSF------LNSLSRIAQGEGTESFQDKMATELLDR 359
            E +   G+L   + +L Q  A ++        L        GE     Q  +AT+    
Sbjct: 767 LEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKAS 826

Query: 360 EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR---------LEVKR--LRNYDCYS 408
             K +  Q+ +  +RE + S+ +    +E  L  L+         LE +R  L++     
Sbjct: 827 LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 886

Query: 409 KDVSYPELQTEILDLHLQVETLSRERTALITAAAS---RALMLERHERAADLFARMVRAR 465
           ++     L+ E  +L  ++  L +ER   +  A S   +AL L+  E+ A L  +++  R
Sbjct: 887 QEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA-LSEKLMGTR 945

Query: 466 KDLAAL 471
             LA +
Sbjct: 946 HSLATI 951



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 81/395 (20%), Positives = 153/395 (38%), Gaps = 27/395 (6%)

Query: 86  DRDTMIKKIERLQKENSILQHKV-----DETSKKENEEPPCHPVQSGSYNYQVLNEELSK 140
           D+  + + + +L++E S LQ +      + T  +E +E             Q L   L  
Sbjct: 614 DKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRV 673

Query: 141 ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
              A+EAL++ + +        + ++A L RQL   + E E A+++ +   + + R A E
Sbjct: 674 AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 733

Query: 201 RSHATVKVKELREQAETAEQVAQSRVSEQKAR----TEFLQAKVAEQEKSKAVAXXXXXX 256
           +     +   L  Q   AE+  ++ +SE+  R     E L+  + E ++  A        
Sbjct: 734 KEALAKEHAGLAVQLVAAEREGRT-LSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 792

Query: 257 XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       ++       L  + +    + +  +E    D+E    K +Q  R A  
Sbjct: 793 LEAEGQALLLAKETLTG---ELAGLRQ----QIIATQEKASLDKELMAQKLVQAEREA-- 843

Query: 317 RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATE-LLDREQKIVKLQQTIDEQRE 375
             +  LR+ RA  +  L  L R  +    E   ++   +  L REQ+  +L   ++ ++E
Sbjct: 844 --QASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE--ELLARLEAEKE 899

Query: 376 NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERT 435
            E S E    Q E     L  E ++ +      K+     L  +++     + T+S E  
Sbjct: 900 -ELSEEIAALQQERDEGLLLAESEKQQALSL--KESEKTALSEKLMGTRHSLATISLEME 956

Query: 436 ALITAAASRALMLERHERAADLFARMVRARKDLAA 470
                A SR         A     R +RA+++ AA
Sbjct: 957 RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 991


>BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein.
          Length = 1132

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 74/371 (19%), Positives = 151/371 (40%), Gaps = 23/371 (6%)

Query: 112 SKKENEEPPCHPVQSGSYNYQVLNE---ELSKERAAREALKEVVASAESMLRVARARIAT 168
           S +    P C    + +  +  L++   ++   R   EA ++++ +    L  + +    
Sbjct: 369 SPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRA 428

Query: 169 LERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE 228
           LE QL+  + + + A + H+D ++ V RL       + +   L    + A+Q A+    E
Sbjct: 429 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQE 488

Query: 229 Q---KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR-DRSIRLVDM-ER 283
           +   +A  E L+ +    E+ +  A                QL+     RS+   ++ E 
Sbjct: 489 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 548

Query: 284 RRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
           R  L     + +     + E+ + L       +  E  + + RAE+ S  +SLS+++   
Sbjct: 549 REALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLS--- 605

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT---QYENQLAALRLEVKR 400
              +  + +A + LD  + + +L++     +  ++  EQ  T   + + +L  LRLE + 
Sbjct: 606 ---ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEV 662

Query: 401 LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFAR 460
            R        +   E   E L+   Q+ TL  ER+ L    A  +  L   E+  +   R
Sbjct: 663 AR--QGLEGSLRVAEQAQEALE--QQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR 718

Query: 461 MVRARKDLAAL 471
              A++ + AL
Sbjct: 719 --EAQRQVEAL 727



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 56/281 (19%), Positives = 124/281 (44%), Gaps = 18/281 (6%)

Query: 125  QSGSYNYQVLNEELSK-ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  S + +++ ++L + ER A+ +L+E  A+ E  L+  +       R+L+  +A+ +  
Sbjct: 823  EKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ-- 880

Query: 184  KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             +  ++ E+L+ RL  E+   + ++  L+++ +    +A+S   +Q+A +      + E 
Sbjct: 881  SQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESE--KQQALS------LKES 932

Query: 244  EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            EK+ A++                  +  RD   R  + +R           +    RE  
Sbjct: 933  EKT-ALSEKLMGTRHSLATISLEMERQKRDAQSRQ-EQDRSTVNALTSELRDLRAQREEA 990

Query: 304  IWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQK 362
                 Q  R    R +E+ R    ++DS L     +  Q    E  +D +  ELL+ ++K
Sbjct: 991  AAAHAQEVR----RLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 1046

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
            + + Q+  + QR+    + +++ +   +  ALR   + LR+
Sbjct: 1047 LRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRS 1087



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 76/366 (20%), Positives = 147/366 (40%), Gaps = 39/366 (10%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L + LSK  A  E+L +       ++       + L+ + +  + E  +A+++ + LE+L
Sbjct: 597 LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEEL 656

Query: 194 -----VNRLAIERS-HATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKS 246
                V R  +E S     + +E  EQ     +  +S++ EQ A+ +  L  +  E E++
Sbjct: 657 RLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 716

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIW 305
           +  A                  +     +++LV  ER  R L          ++  T + 
Sbjct: 717 RREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL----------SEEATRLR 766

Query: 306 KELQMTRGALLRSEEELRQSRAEKDSF------LNSLSRIAQGEGTESFQDKMATELLDR 359
            E +   G+L   + +L Q  A ++        L        GE     Q  +AT+    
Sbjct: 767 LEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKAS 826

Query: 360 EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR---------LEVKR--LRNYDCYS 408
             K +  Q+ +  +RE + S+ +    +E  L  L+         LE +R  L++     
Sbjct: 827 LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 886

Query: 409 KDVSYPELQTEILDLHLQVETLSRERTALITAAAS---RALMLERHERAADLFARMVRAR 465
           ++     L+ E  +L  ++  L +ER   +  A S   +AL L+  E+ A L  +++  R
Sbjct: 887 QEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA-LSEKLMGTR 945

Query: 466 KDLAAL 471
             LA +
Sbjct: 946 HSLATI 951



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 81/395 (20%), Positives = 153/395 (38%), Gaps = 27/395 (6%)

Query: 86  DRDTMIKKIERLQKENSILQHKV-----DETSKKENEEPPCHPVQSGSYNYQVLNEELSK 140
           D+  + + + +L++E S LQ +      + T  +E +E             Q L   L  
Sbjct: 614 DKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRV 673

Query: 141 ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
              A+EAL++ + +        + ++A L RQL   + E E A+++ +   + + R A E
Sbjct: 674 AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 733

Query: 201 RSHATVKVKELREQAETAEQVAQSRVSEQKAR----TEFLQAKVAEQEKSKAVAXXXXXX 256
           +     +   L  Q   AE+  ++ +SE+  R     E L+  + E ++  A        
Sbjct: 734 KEALAKEHAGLAVQLVAAEREGRT-LSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 792

Query: 257 XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       ++       L  + +    + +  +E    D+E    K +Q  R A  
Sbjct: 793 LEAEGQALLLAKETLTG---ELAGLRQ----QIIATQEKASLDKELMAQKLVQAEREA-- 843

Query: 317 RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATE-LLDREQKIVKLQQTIDEQRE 375
             +  LR+ RA  +  L  L R  +    E   ++   +  L REQ+  +L   ++ ++E
Sbjct: 844 --QASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE--ELLARLEAEKE 899

Query: 376 NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERT 435
            E S E    Q E     L  E ++ +      K+     L  +++     + T+S E  
Sbjct: 900 -ELSEEIAALQQERDEGLLLAESEKQQALSL--KESEKTALSEKLMGTRHSLATISLEME 956

Query: 436 ALITAAASRALMLERHERAADLFARMVRARKDLAA 470
                A SR         A     R +RA+++ AA
Sbjct: 957 RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 991


>AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein.
          Length = 1203

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 83/409 (20%), Positives = 165/409 (40%), Gaps = 34/409 (8%)

Query: 20   RDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI 79
            R++E     A +T  +V VL     +T+    +   ER  + VAG   +   ++   L +
Sbjct: 612  RELEQARASAGDTR-QVEVLKKELLRTQEELKELQAERQSQEVAG--RHRDRELEKQLAV 668

Query: 80   AKIPWLDRDTMIKKIERLQKENSILQHKVD-ETSKKENEEPPCHPVQSGSYNYQVLNEEL 138
             ++   DR   +++ + LQ + ++ Q + D E + K            G     V    L
Sbjct: 669  LRVE-ADRGRELEE-QNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAV-ETTL 725

Query: 139  SKERAAREALKEVVASAESMLRVARARI---ATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
             + +   +  +  +   E  L+  R  +     +E +L+D     E  K++   LE+ +N
Sbjct: 726  RETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQ---LEEALN 782

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQE---KSKAVAXX 252
                E        + L  + E A++       EQ+     L+ +  ++E   + KA    
Sbjct: 783  ASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEE 842

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIW-KELQ 309
                          +L+   + S + +   + +  +Y      E  D  R+ + W  E +
Sbjct: 843  QKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAE 902

Query: 310  MTRGALLRSEEE---LRQ----SRAEKDSFLNSLSRIAQ--------GEGTESFQDKMAT 354
             T G L R ++E   LRQ    S+AE+D+       +AQ         E  +  QD  A 
Sbjct: 903  KTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRAR 962

Query: 355  ELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
            +L   E+K+ +L+  +DE++   + +   + +  +Q+  LR E+ + R+
Sbjct: 963  QLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERS 1011



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 74/321 (23%), Positives = 131/321 (40%), Gaps = 30/321 (9%)

Query: 104 LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVAR 163
           LQ K+DE  KK  +     P Q G      L  +L ++      L+E++   +   + + 
Sbjct: 371 LQRKLDEEVKKRQK---LEPSQVG------LERQLEEKTEECSRLQELLERRKGEAQQSN 421

Query: 164 ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ 223
             +  ++R L   +      + +  +L+  +  +        V +K+L E  E  E+V +
Sbjct: 422 KELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLE 481

Query: 224 S--RVSEQ-KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRD--RSIR 277
              RV EQ + R   L A     ++  A                  QL+ S +D  +   
Sbjct: 482 GKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHA 541

Query: 278 LVDMERRRCLEYVPC--KENEPTDRETEIWKEL-QMTRGALLRSEEELRQSRAEKDSFLN 334
           +++ ER++    V    +E E T  ET  W+ + Q  +  L  +++EL Q R EK+    
Sbjct: 542 VLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEE 601

Query: 335 SLSR---IAQGE---GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME----QTM 384
            L     + Q E      S  D    E+L +E  +++ Q+ + E +   +S E       
Sbjct: 602 ELGEKIEVLQRELEQARASAGDTRQVEVLKKE--LLRTQEELKELQAERQSQEVAGRHRD 659

Query: 385 TQYENQLAALRLEVKRLRNYD 405
            + E QLA LR+E  R R  +
Sbjct: 660 RELEKQLAVLRVEADRGRELE 680



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 39/165 (23%), Positives = 75/165 (45%), Gaps = 8/165 (4%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            +D   ++++ L+++ S L+ ++DE  +K   E     V  G      L  EL +ER+AR+
Sbjct: 957  QDDRARQLKGLEEKVSRLETELDE--EKNTVELLTDRVNRGRDQVDQLRTELMQERSARQ 1014

Query: 147  ALKEVVASAESMLRVARARIATLE------RQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
             L+    S E   +  + R+A+ E        L   +++ ++ +++ +  E+    L   
Sbjct: 1015 DLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQST 1074

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEK 245
                  KVKEL  Q E   Q    +  +   R + L+ +V E E+
Sbjct: 1075 NRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEE 1119



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 56/287 (19%), Positives = 119/287 (41%), Gaps = 15/287 (5%)

Query: 91  IKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
           ++ ++RL  +   L+H + ET   E +    H VQ      +VL ++L + R   E + E
Sbjct: 424 LQNMKRLLDQGEDLRHGL-ETQVMELQNKLKH-VQGPEPAKEVLLKDLLETRELLEEVLE 481

Query: 151 VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE 210
                E  LR+    +  L+  LK+     E+A +     +Q V  +  +    T +++ 
Sbjct: 482 GKQRVEEQLRLRERELTALKGALKE-----EVASR-----DQEVEHVRQQYQRDTEQLRR 531

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             + A     V ++   +  A    LQ ++ E  +                     +L  
Sbjct: 532 SMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQ 591

Query: 271 FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
            R     + + E    +E +  +E E         +++++ +  LLR++EEL++ +AE+ 
Sbjct: 592 LRMEKEEMEE-ELGEKIEVLQ-RELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQ 649

Query: 331 S-FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
           S  +    R  + E   +     A    + E++ ++LQ+T+ + R++
Sbjct: 650 SQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQD 696


>AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet
           coiled-coil, rootletin protein.
          Length = 1898

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 74/371 (19%), Positives = 151/371 (40%), Gaps = 23/371 (6%)

Query: 112 SKKENEEPPCHPVQSGSYNYQVLNE---ELSKERAAREALKEVVASAESMLRVARARIAT 168
           S +    P C    + +  +  L++   ++   R   EA ++++ +    L  + +    
Sbjct: 387 SPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRA 446

Query: 169 LERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE 228
           LE QL+  + + + A + H+D ++ V RL       + +   L    + A+Q A+    E
Sbjct: 447 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQE 506

Query: 229 Q---KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR-DRSIRLVDM-ER 283
           +   +A  E L+ +    E+ +  A                QL+     RS+   ++ E 
Sbjct: 507 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 566

Query: 284 RRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
           R  L     + +     + E+ + L       +  E  + + RAE+ S  +SLS+++   
Sbjct: 567 REALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLS--- 623

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT---QYENQLAALRLEVKR 400
              +  + +A + LD  + + +L++     +  ++  EQ  T   + + +L  LRLE + 
Sbjct: 624 ---ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEV 680

Query: 401 LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFAR 460
            R        +   E   E L+   Q+ TL  ER+ L    A  +  L   E+  +   R
Sbjct: 681 AR--QGLEGSLRVAEQAQEALE--QQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR 736

Query: 461 MVRARKDLAAL 471
              A++ + AL
Sbjct: 737 --EAQRQVEAL 745



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 69/334 (20%), Positives = 145/334 (43%), Gaps = 23/334 (6%)

Query: 125  QSGSYNYQVLNEELSK-ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  S + +++ ++L + ER A+ +L+E  A+ E  L+  +       R+L+  +A+ +  
Sbjct: 841  EKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ-- 898

Query: 184  KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             +  ++ E+L+ RL  E+   + ++  L+++ +    +A+S   +Q+A +      + E 
Sbjct: 899  SQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESE--KQQALS------LKES 950

Query: 244  EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            EK+ A++                  +  RD   R  + +R           +    RE  
Sbjct: 951  EKT-ALSEKLMGTRHSLATISLEMERQKRDAQSRQ-EQDRSTVNALTSELRDLRAQREEA 1008

Query: 304  IWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQK 362
                 Q  R    R +E+ R    ++DS L     +  Q    E  +D +  ELL+ ++K
Sbjct: 1009 AAAHAQEVR----RLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 1064

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN--YDCYSKDVSYPELQTEI 420
            + + Q+  + QR+    + +++ +   +  ALR   + LR+      S+ +S  +L  E 
Sbjct: 1065 LRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISL-KLANE- 1122

Query: 421  LDLHLQVETLSRERTALITAAASRALMLERHERA 454
             D   ++  L   RTA+   A      L+  ER+
Sbjct: 1123 -DKEQKLALLEEARTAVGKEAGELRTGLQEVERS 1155



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 69/313 (22%), Positives = 127/313 (40%), Gaps = 20/313 (6%)

Query: 138  LSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEF-----EIAKKKHKD--L 190
            LS  +A     +E V  +E   R    ++ATLER L+ T++E      +I+K K  +  L
Sbjct: 1455 LSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKL 1514

Query: 191  EQLVNRL--AIERSHA-TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
            E    RL   ++ S + TVK++  R   E   Q ++  +S+++A+ + LQ +V   ++  
Sbjct: 1515 EGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQV 1574

Query: 248  AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKENEPTDRETEIW 305
            A +                 L    +    L D  R     L       N   D+   + 
Sbjct: 1575 ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQ 1634

Query: 306  KEL---QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
            K L   +  R  L    +  RQ+ +E     +SL     GE  ++ + ++A   L R + 
Sbjct: 1635 KALTACEHDRQVLQERLDAARQALSEARKQSSSL-----GEQVQTLRGEVADLELQRVEA 1689

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILD 422
              +LQQ  +  R+ ++     +   +      RL  +RL +       +   + + E   
Sbjct: 1690 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1749

Query: 423  LHLQVETLSRERT 435
            L L+ + ++  RT
Sbjct: 1750 LRLEKDRVALRRT 1762



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 76/366 (20%), Positives = 147/366 (40%), Gaps = 39/366 (10%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L + LSK  A  E+L +       ++       + L+ + +  + E  +A+++ + LE+L
Sbjct: 615 LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEEL 674

Query: 194 -----VNRLAIERS-HATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKS 246
                V R  +E S     + +E  EQ     +  +S++ EQ A+ +  L  +  E E++
Sbjct: 675 RLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 734

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIW 305
           +  A                  +     +++LV  ER  R L          ++  T + 
Sbjct: 735 RREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL----------SEEATRLR 784

Query: 306 KELQMTRGALLRSEEELRQSRAEKDSF------LNSLSRIAQGEGTESFQDKMATELLDR 359
            E +   G+L   + +L Q  A ++        L        GE     Q  +AT+    
Sbjct: 785 LEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKAS 844

Query: 360 EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR---------LEVKR--LRNYDCYS 408
             K +  Q+ +  +RE + S+ +    +E  L  L+         LE +R  L++     
Sbjct: 845 LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 904

Query: 409 KDVSYPELQTEILDLHLQVETLSRERTALITAAAS---RALMLERHERAADLFARMVRAR 465
           ++     L+ E  +L  ++  L +ER   +  A S   +AL L+  E+ A L  +++  R
Sbjct: 905 QEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA-LSEKLMGTR 963

Query: 466 KDLAAL 471
             LA +
Sbjct: 964 HSLATI 969



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 72/311 (23%), Positives = 129/311 (41%), Gaps = 30/311 (9%)

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELS-----KERAAREALKEVVASAESML 159
            + K D  S++E +    + + S   + +   EE +     + R  +E  +++    +S L
Sbjct: 975  RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCL 1034

Query: 160  RVARARIATLERQLKDTKAEF--EIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET 217
            R A   + T  R L+D +     E+ + + K  E    R  ++R  A    + L E A+ 
Sbjct: 1035 REAE-ELRTQLRLLEDARDGLRRELLEAQRKLRESQEGR-EVQRQEAGELRRSLGEGAKE 1092

Query: 218  AEQVAQS----RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
             E + +S    R + +KA +E +  K+A ++K + +A                +      
Sbjct: 1093 REALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEV 1152

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
               RL   E RR L+ +  +        T + +EL   +G L   E   ++SR E    L
Sbjct: 1153 ERSRL---EARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRET---L 1206

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEK----SMEQTMTQYEN 389
                R+ +GE +    + M  EL   ++   KLQ+   E R  E+    S+E+     + 
Sbjct: 1207 GLRQRLLKGEAS---LEVMRQELQVAQR---KLQEQEGEFRTRERRLLGSLEEARGTEKQ 1260

Query: 390  QLAALR-LEVK 399
            QL   R LE+K
Sbjct: 1261 QLDHARGLELK 1271



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 32/146 (21%), Positives = 73/146 (50%), Gaps = 8/146 (5%)

Query: 91   IKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            +  +++LQ E  +LQ ++    +   + E     V+  +   +   + ++  R   +  +
Sbjct: 1711 LNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLE--KDRVALRRTLDKVER 1768

Query: 150  EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAI-ERSHATVKV 208
            E + S E  +R++ A    L+R L  T AE E+A+ + + ++QL  ++ + E+SH+  ++
Sbjct: 1769 EKLRSHEDTVRLS-AEKGRLDRTL--TGAELELAEAQ-RQIQQLEAQVVVLEQSHSPAQL 1824

Query: 209  KELREQAETAEQVAQSRVSEQKARTE 234
            +   +Q +   Q    R+   +A+TE
Sbjct: 1825 EVDAQQQQLELQQEVERLRSAQAQTE 1850



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 81/395 (20%), Positives = 153/395 (38%), Gaps = 27/395 (6%)

Query: 86   DRDTMIKKIERLQKENSILQHKV-----DETSKKENEEPPCHPVQSGSYNYQVLNEELSK 140
            D+  + + + +L++E S LQ +      + T  +E +E             Q L   L  
Sbjct: 632  DKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRV 691

Query: 141  ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
               A+EAL++ + +        + ++A L RQL   + E E A+++ +   + + R A E
Sbjct: 692  AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 751

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKAR----TEFLQAKVAEQEKSKAVAXXXXXX 256
            +     +   L  Q   AE+  ++ +SE+  R     E L+  + E ++  A        
Sbjct: 752  KEALAKEHAGLAVQLVAAEREGRT-LSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 810

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                        ++       L  + +    + +  +E    D+E    K +Q  R A  
Sbjct: 811  LEAEGQALLLAKETLTG---ELAGLRQ----QIIATQEKASLDKELMAQKLVQAEREA-- 861

Query: 317  RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATE-LLDREQKIVKLQQTIDEQRE 375
              +  LR+ RA  +  L  L R  +    E   ++   +  L REQ+  +L   ++ ++E
Sbjct: 862  --QASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE--ELLARLEAEKE 917

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERT 435
             E S E    Q E     L  E ++ +      K+     L  +++     + T+S E  
Sbjct: 918  -ELSEEIAALQQERDEGLLLAESEKQQALSL--KESEKTALSEKLMGTRHSLATISLEME 974

Query: 436  ALITAAASRALMLERHERAADLFARMVRARKDLAA 470
                 A SR         A     R +RA+++ AA
Sbjct: 975  RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 1009



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 6/86 (6%)

Query: 306 KELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQD-KMATELLDREQK-- 362
           +E Q+ +  L R E+ L QSRAE+D      + +++ + TE  QD + A   L+ EQ+  
Sbjct: 52  EENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERD-TEHSQDLESALIRLEEEQQRS 110

Query: 363 --IVKLQQTIDEQRENEKSMEQTMTQ 386
             + ++   + EQ +   S  Q +++
Sbjct: 111 ASLAQVNAMLREQLDQAGSANQALSE 136


>AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet
           coiled-coil, rootletin protein.
          Length = 2017

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 74/371 (19%), Positives = 151/371 (40%), Gaps = 23/371 (6%)

Query: 112 SKKENEEPPCHPVQSGSYNYQVLNE---ELSKERAAREALKEVVASAESMLRVARARIAT 168
           S +    P C    + +  +  L++   ++   R   EA ++++ +    L  + +    
Sbjct: 506 SPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRA 565

Query: 169 LERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE 228
           LE QL+  + + + A + H+D ++ V RL       + +   L    + A+Q A+    E
Sbjct: 566 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQE 625

Query: 229 Q---KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR-DRSIRLVDM-ER 283
           +   +A  E L+ +    E+ +  A                QL+     RS+   ++ E 
Sbjct: 626 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 685

Query: 284 RRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
           R  L     + +     + E+ + L       +  E  + + RAE+ S  +SLS+++   
Sbjct: 686 REALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLS--- 742

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT---QYENQLAALRLEVKR 400
              +  + +A + LD  + + +L++     +  ++  EQ  T   + + +L  LRLE + 
Sbjct: 743 ---ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEV 799

Query: 401 LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFAR 460
            R        +   E   E L+   Q+ TL  ER+ L    A  +  L   E+  +   R
Sbjct: 800 AR--QGLEGSLRVAEQAQEALE--QQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR 855

Query: 461 MVRARKDLAAL 471
              A++ + AL
Sbjct: 856 --EAQRQVEAL 864



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 69/334 (20%), Positives = 145/334 (43%), Gaps = 23/334 (6%)

Query: 125  QSGSYNYQVLNEELSK-ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  S + +++ ++L + ER A+ +L+E  A+ E  L+  +       R+L+  +A+ +  
Sbjct: 960  EKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ-- 1017

Query: 184  KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             +  ++ E+L+ RL  E+   + ++  L+++ +    +A+S   +Q+A +      + E 
Sbjct: 1018 SQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESE--KQQALS------LKES 1069

Query: 244  EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            EK+ A++                  +  RD   R  + +R           +    RE  
Sbjct: 1070 EKT-ALSEKLMGTRHSLATISLEMERQKRDAQSRQ-EQDRSTVNALTSELRDLRAQREEA 1127

Query: 304  IWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQK 362
                 Q  R    R +E+ R    ++DS L     +  Q    E  +D +  ELL+ ++K
Sbjct: 1128 AAAHAQEVR----RLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 1183

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN--YDCYSKDVSYPELQTEI 420
            + + Q+  + QR+    + +++ +   +  ALR   + LR+      S+ +S  +L  E 
Sbjct: 1184 LRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISL-KLANE- 1241

Query: 421  LDLHLQVETLSRERTALITAAASRALMLERHERA 454
             D   ++  L   RTA+   A      L+  ER+
Sbjct: 1242 -DKEQKLALLEEARTAVGKEAGELRTGLQEVERS 1274



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 69/313 (22%), Positives = 127/313 (40%), Gaps = 20/313 (6%)

Query: 138  LSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEF-----EIAKKKHKD--L 190
            LS  +A     +E V  +E   R    ++ATLER L+ T++E      +I+K K  +  L
Sbjct: 1574 LSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKL 1633

Query: 191  EQLVNRL--AIERSHA-TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
            E    RL   ++ S + TVK++  R   E   Q ++  +S+++A+ + LQ +V   ++  
Sbjct: 1634 EGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQV 1693

Query: 248  AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKENEPTDRETEIW 305
            A +                 L    +    L D  R     L       N   D+   + 
Sbjct: 1694 ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQ 1753

Query: 306  KEL---QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
            K L   +  R  L    +  RQ+ +E     +SL     GE  ++ + ++A   L R + 
Sbjct: 1754 KALTACEHDRQVLQERLDAARQALSEARKQSSSL-----GEQVQTLRGEVADLELQRVEA 1808

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILD 422
              +LQQ  +  R+ ++     +   +      RL  +RL +       +   + + E   
Sbjct: 1809 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1868

Query: 423  LHLQVETLSRERT 435
            L L+ + ++  RT
Sbjct: 1869 LRLEKDRVALRRT 1881



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 76/366 (20%), Positives = 147/366 (40%), Gaps = 39/366 (10%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L + LSK  A  E+L +       ++       + L+ + +  + E  +A+++ + LE+L
Sbjct: 734  LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEEL 793

Query: 194  -----VNRLAIERS-HATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKS 246
                 V R  +E S     + +E  EQ     +  +S++ EQ A+ +  L  +  E E++
Sbjct: 794  RLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 853

Query: 247  KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIW 305
            +  A                  +     +++LV  ER  R L          ++  T + 
Sbjct: 854  RREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL----------SEEATRLR 903

Query: 306  KELQMTRGALLRSEEELRQSRAEKDSF------LNSLSRIAQGEGTESFQDKMATELLDR 359
             E +   G+L   + +L Q  A ++        L        GE     Q  +AT+    
Sbjct: 904  LEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKAS 963

Query: 360  EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR---------LEVKR--LRNYDCYS 408
              K +  Q+ +  +RE + S+ +    +E  L  L+         LE +R  L++     
Sbjct: 964  LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 1023

Query: 409  KDVSYPELQTEILDLHLQVETLSRERTALITAAAS---RALMLERHERAADLFARMVRAR 465
            ++     L+ E  +L  ++  L +ER   +  A S   +AL L+  E+ A L  +++  R
Sbjct: 1024 QEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA-LSEKLMGTR 1082

Query: 466  KDLAAL 471
              LA +
Sbjct: 1083 HSLATI 1088



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 72/311 (23%), Positives = 129/311 (41%), Gaps = 30/311 (9%)

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELS-----KERAAREALKEVVASAESML 159
            + K D  S++E +    + + S   + +   EE +     + R  +E  +++    +S L
Sbjct: 1094 RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCL 1153

Query: 160  RVARARIATLERQLKDTKAEF--EIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET 217
            R A   + T  R L+D +     E+ + + K  E    R  ++R  A    + L E A+ 
Sbjct: 1154 REAE-ELRTQLRLLEDARDGLRRELLEAQRKLRESQEGR-EVQRQEAGELRRSLGEGAKE 1211

Query: 218  AEQVAQS----RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
             E + +S    R + +KA +E +  K+A ++K + +A                +      
Sbjct: 1212 REALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEV 1271

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
               RL   E RR L+ +  +        T + +EL   +G L   E   ++SR E    L
Sbjct: 1272 ERSRL---EARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRET---L 1325

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEK----SMEQTMTQYEN 389
                R+ +GE +    + M  EL   ++   KLQ+   E R  E+    S+E+     + 
Sbjct: 1326 GLRQRLLKGEAS---LEVMRQELQVAQR---KLQEQEGEFRTRERRLLGSLEEARGTEKQ 1379

Query: 390  QLAALR-LEVK 399
            QL   R LE+K
Sbjct: 1380 QLDHARGLELK 1390



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 32/146 (21%), Positives = 73/146 (50%), Gaps = 8/146 (5%)

Query: 91   IKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            +  +++LQ E  +LQ ++    +   + E     V+  +   +   + ++  R   +  +
Sbjct: 1830 LNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLE--KDRVALRRTLDKVER 1887

Query: 150  EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAI-ERSHATVKV 208
            E + S E  +R++ A    L+R L  T AE E+A+ + + ++QL  ++ + E+SH+  ++
Sbjct: 1888 EKLRSHEDTVRLS-AEKGRLDRTL--TGAELELAEAQ-RQIQQLEAQVVVLEQSHSPAQL 1943

Query: 209  KELREQAETAEQVAQSRVSEQKARTE 234
            +   +Q +   Q    R+   +A+TE
Sbjct: 1944 EVDAQQQQLELQQEVERLRSAQAQTE 1969



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 81/395 (20%), Positives = 153/395 (38%), Gaps = 27/395 (6%)

Query: 86   DRDTMIKKIERLQKENSILQHKV-----DETSKKENEEPPCHPVQSGSYNYQVLNEELSK 140
            D+  + + + +L++E S LQ +      + T  +E +E             Q L   L  
Sbjct: 751  DKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRV 810

Query: 141  ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
               A+EAL++ + +        + ++A L RQL   + E E A+++ +   + + R A E
Sbjct: 811  AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 870

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKAR----TEFLQAKVAEQEKSKAVAXXXXXX 256
            +     +   L  Q   AE+  ++ +SE+  R     E L+  + E ++  A        
Sbjct: 871  KEALAKEHAGLAVQLVAAEREGRT-LSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 929

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                        ++       L  + +    + +  +E    D+E    K +Q  R A  
Sbjct: 930  LEAEGQALLLAKETLTG---ELAGLRQ----QIIATQEKASLDKELMAQKLVQAEREA-- 980

Query: 317  RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATE-LLDREQKIVKLQQTIDEQRE 375
              +  LR+ RA  +  L  L R  +    E   ++   +  L REQ+  +L   ++ ++E
Sbjct: 981  --QASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE--ELLARLEAEKE 1036

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERT 435
             E S E    Q E     L  E ++ +      K+     L  +++     + T+S E  
Sbjct: 1037 -ELSEEIAALQQERDEGLLLAESEKQQALSL--KESEKTALSEKLMGTRHSLATISLEME 1093

Query: 436  ALITAAASRALMLERHERAADLFARMVRARKDLAA 470
                 A SR         A     R +RA+++ AA
Sbjct: 1094 RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 1128


>AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein.
          Length = 1203

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 83/409 (20%), Positives = 165/409 (40%), Gaps = 34/409 (8%)

Query: 20   RDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI 79
            R++E     A +T  +V VL     +T+    +   ER  + VAG   +   ++   L +
Sbjct: 612  RELEQARASAGDTR-QVEVLKKELLRTQEELKELQAERQSQEVAG--RHRDRELEKQLAV 668

Query: 80   AKIPWLDRDTMIKKIERLQKENSILQHKVD-ETSKKENEEPPCHPVQSGSYNYQVLNEEL 138
             ++   DR   +++ + LQ + ++ Q + D E + K            G     V    L
Sbjct: 669  LRVE-ADRGRELEE-QNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAV-ETTL 725

Query: 139  SKERAAREALKEVVASAESMLRVARARI---ATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
             + +   +  +  +   E  L+  R  +     +E +L+D     E  K++   LE+ +N
Sbjct: 726  RETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQ---LEEALN 782

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQE---KSKAVAXX 252
                E        + L  + E A++       EQ+     L+ +  ++E   + KA    
Sbjct: 783  ASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEE 842

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIW-KELQ 309
                          +L+   + S + +   + +  +Y      E  D  R+ + W  E +
Sbjct: 843  QKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAE 902

Query: 310  MTRGALLRSEEE---LRQ----SRAEKDSFLNSLSRIAQ--------GEGTESFQDKMAT 354
             T G L R ++E   LRQ    S+AE+D+       +AQ         E  +  QD  A 
Sbjct: 903  KTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRAR 962

Query: 355  ELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
            +L   E+K+ +L+  +DE++   + +   + +  +Q+  LR E+ + R+
Sbjct: 963  QLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERS 1011



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 74/321 (23%), Positives = 131/321 (40%), Gaps = 30/321 (9%)

Query: 104 LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVAR 163
           LQ K+DE  KK  +     P Q G      L  +L ++      L+E++   +   + + 
Sbjct: 371 LQRKLDEEVKKRQK---LEPSQVG------LERQLEEKTEECSRLQELLERRKGEAQQSN 421

Query: 164 ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ 223
             +  ++R L   +      + +  +L+  +  +        V +K+L E  E  E+V +
Sbjct: 422 KELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLE 481

Query: 224 S--RVSEQ-KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRD--RSIR 277
              RV EQ + R   L A     ++  A                  QL+ S +D  +   
Sbjct: 482 GKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHA 541

Query: 278 LVDMERRRCLEYVPC--KENEPTDRETEIWKEL-QMTRGALLRSEEELRQSRAEKDSFLN 334
           +++ ER++    V    +E E T  ET  W+ + Q  +  L  +++EL Q R EK+    
Sbjct: 542 VLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEE 601

Query: 335 SLSR---IAQGE---GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME----QTM 384
            L     + Q E      S  D    E+L +E  +++ Q+ + E +   +S E       
Sbjct: 602 ELGEKIEVLQRELEQARASAGDTRQVEVLKKE--LLRTQEELKELQAERQSQEVAGRHRD 659

Query: 385 TQYENQLAALRLEVKRLRNYD 405
            + E QLA LR+E  R R  +
Sbjct: 660 RELEKQLAVLRVEADRGRELE 680



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 39/165 (23%), Positives = 75/165 (45%), Gaps = 8/165 (4%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            +D   ++++ L+++ S L+ ++DE  +K   E     V  G      L  EL +ER+AR+
Sbjct: 957  QDDRARQLKGLEEKVSRLETELDE--EKNTVELLTDRVNRGRDQVDQLRTELMQERSARQ 1014

Query: 147  ALKEVVASAESMLRVARARIATLE------RQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
             L+    S E   +  + R+A+ E        L   +++ ++ +++ +  E+    L   
Sbjct: 1015 DLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQST 1074

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEK 245
                  KVKEL  Q E   Q    +  +   R + L+ +V E E+
Sbjct: 1075 NRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEE 1119



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 56/287 (19%), Positives = 119/287 (41%), Gaps = 15/287 (5%)

Query: 91  IKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
           ++ ++RL  +   L+H + ET   E +    H VQ      +VL ++L + R   E + E
Sbjct: 424 LQNMKRLLDQGEDLRHGL-ETQVMELQNKLKH-VQGPEPAKEVLLKDLLETRELLEEVLE 481

Query: 151 VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE 210
                E  LR+    +  L+  LK+     E+A +     +Q V  +  +    T +++ 
Sbjct: 482 GKQRVEEQLRLRERELTALKGALKE-----EVASR-----DQEVEHVRQQYQRDTEQLRR 531

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             + A     V ++   +  A    LQ ++ E  +                     +L  
Sbjct: 532 SMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQ 591

Query: 271 FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
            R     + + E    +E +  +E E         +++++ +  LLR++EEL++ +AE+ 
Sbjct: 592 LRMEKEEMEE-ELGEKIEVLQ-RELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQ 649

Query: 331 S-FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
           S  +    R  + E   +     A    + E++ ++LQ+T+ + R++
Sbjct: 650 SQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQD 696


>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
            protein.
          Length = 2585

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 71/337 (21%), Positives = 144/337 (42%), Gaps = 32/337 (9%)

Query: 86   DRDTMIKKIER-LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
            +++T I  I++ L+  N  LQ+K+ E  +KE +           +N + ++E   K    
Sbjct: 1482 EKETEISTIQKQLEAINDKLQNKIQEIYEKEEQ-----------FNIKQISEVQEKVNEL 1530

Query: 145  REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            ++  KE   + +S L+   +++  L  +L++++ E +I  K+ ++++++   L IER   
Sbjct: 1531 KQ-FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQL 1589

Query: 205  TVKVKE----LREQAETAEQ----VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
                KE    ++E  E   Q     A +   E+    E L+ +   Q+ +          
Sbjct: 1590 KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIR 1649

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN--EPTDRETEIWKELQMTRGA 314
                      +++S       L  +E    +E    KEN  E   R+ E  +EL++    
Sbjct: 1650 LTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMH 1709

Query: 315  LLRSEE---ELRQSRAEKDSFLNSLSR-IAQGEGTESFQD-KMATELLDREQKIVKLQQT 369
            L   +E   +LR   +EK + ++++ + +         QD K+  EL      + + Q+T
Sbjct: 1710 LKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQET 1769

Query: 370  IDEQR----ENEKSMEQTMTQYENQLAALRLEVKRLR 402
            ID+ R    E    +       EN  A L+ +++ L+
Sbjct: 1770 IDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELK 1806



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 69/349 (19%), Positives = 154/349 (44%), Gaps = 51/349 (14%)

Query: 128  SYNYQVLNE---ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAK 184
            SY  Q L E   E+ +     E LKE + + +S L+        +  +L+ T  E +   
Sbjct: 849  SYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLT 908

Query: 185  KKHKDLEQLVNRLAIERS------HATVKV-----KELREQAETAEQ------VAQSRVS 227
            ++  DL+QL   L IER       H TV +     ++LR   E+ +Q        +S++S
Sbjct: 909  QEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKIS 968

Query: 228  EQKARTEFLQAKVAE-----QEKSKAVAXXXXXXXXXXXXXXXXQLQS---FRDRSIRLV 279
            E+ +R   ++    E     Q+K   +                    +    + R I  +
Sbjct: 969  EEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSL 1028

Query: 280  DMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR----QSRAEKDSFLNS 335
              E+    + +     E    +T++ + ++MT    + ++EELR    + + +++     
Sbjct: 1029 IQEKNELQQMLESVIAEKEQLKTDLKENIEMT----IENQEELRLLGDELKKQQEIVAQE 1084

Query: 336  LSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
             +   + EG  S   +    L + E+K+ +  Q + E+++   ++++ M++ + ++    
Sbjct: 1085 KNHAIKKEGELS---RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKIN--- 1138

Query: 396  LEVKRLRNYDCYSKDVSYPELQTEILDL-------HLQVETLSRERTAL 437
             E++ L+N +  +K+++   ++TE L+L       + +V+++++ER  L
Sbjct: 1139 -EIENLKN-ELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVL 1185



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 75/345 (21%), Positives = 149/345 (43%), Gaps = 29/345 (8%)

Query: 99   KENSILQHKVDETSK-KENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES 157
            K+ S +Q KV+E  + KE+ +     +QS       L   L +   ++E ++ ++   E 
Sbjct: 1518 KQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQE---SQEEIQIMIKEKEE 1574

Query: 158  MLRVARARIATLER-QLKDTKAEFEIAKKKHKDLE-QLVNRLAI-ERSHATVKVKELREQ 214
            M RV  A    +ER QLK+   E     K+ ++ E Q +   A+ E      +++ L+EQ
Sbjct: 1575 MKRVQEA--LQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQ 1632

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
             ET +   ++  +E    T+ L   + E                          ++ R+ 
Sbjct: 1633 FETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRET 1692

Query: 275  SIRLVDMERRRCLEYVPCKENEPT---------DRETEI---WKELQMTRGAL----LRS 318
              R ++ +    + ++  KE++ T         ++  EI    K+L+ +  AL    L+ 
Sbjct: 1693 ITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKI 1752

Query: 319  EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
            +EELR +         ++ ++ +G  +E   DK++    D E    KLQ+ I E + NE 
Sbjct: 1753 QEELRIAHMHLKEQQETIDKL-RGIVSEK-TDKLSNMQKDLENSNAKLQEKIQELKANEH 1810

Query: 379  SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDL 423
             +  T+ +  N+      E+++L+      + ++  +L+ E L+L
Sbjct: 1811 QL-ITLKKDVNETQKKVSEMEQLKK-QIKDQSLTLSKLEIENLNL 1853



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 59/308 (19%), Positives = 120/308 (38%), Gaps = 13/308 (4%)

Query: 166  IATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSR 225
            +AT +   K T  EF+  K  H D EQ    +  E      ++  L ++A+  +    + 
Sbjct: 785  LATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGAL 844

Query: 226  VSEQKARTEFLQAKVAE-QEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR 284
             +E   +T+ LQ K  E QE+   +                  LQ+  +R   L+  + +
Sbjct: 845  KTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDST-----LQTV-EREKTLITEKLQ 898

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGALLRS-EEELRQSRAEKDSFLNSLSRIAQGE 343
            + LE V     E  D + ++ + LQ+ R  L     + +  +   ++   N+L  + Q +
Sbjct: 899  QTLEEVKTLTQEKDDLK-QLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQ 957

Query: 344  GT-ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
             T  + + K++ E+           +T DE ++    +++           L  +VK   
Sbjct: 958  ETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNE 1017

Query: 403  NYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMV 462
              +   K  S   L  E  +L   +E++  E+  L T       M   ++    L    +
Sbjct: 1018 IIEQQRKIFS---LIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDEL 1074

Query: 463  RARKDLAA 470
            + ++++ A
Sbjct: 1075 KKQQEIVA 1082



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 66/338 (19%), Positives = 135/338 (39%), Gaps = 22/338 (6%)

Query: 90   MIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            M KKI  ++   + L++K  E + +  E       Q  + NY+ + + ++KER   + LK
Sbjct: 1133 MQKKINEIENLKNELKNK--ELTLEHMETERLELAQKLNENYEEV-KSITKER---KVLK 1186

Query: 150  EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVK 209
            E+  S E+     R  I  +E     TK E +IA    K+ ++ ++ L    S  T ++ 
Sbjct: 1187 ELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQII 1246

Query: 210  ELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
              ++  E +    Q  +       E L    +V+E +++                    +
Sbjct: 1247 NTQD-LEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLAR 1305

Query: 268  LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRET------EIWKELQMTRGALLRSEEE 321
            ++  R R        +         ++N  T +E       ++ + ++ T   +  S+ +
Sbjct: 1306 IEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSK 1365

Query: 322  LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME 381
              QS   K+   N  ++I      E F+ K  + LL  E +++ L + + E  +  KS+ 
Sbjct: 1366 QEQSLNMKEKD-NETTKIV--SEMEQFKPK-DSALLRIEIEMLGLSKRLQESHDEMKSVA 1421

Query: 382  QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
            +     +     L+ E  +L+      K++    L+TE
Sbjct: 1422 KEKDDLQRLQEVLQSESDQLKE---NIKEIVAKHLETE 1456



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 69/354 (19%), Positives = 149/354 (42%), Gaps = 26/354 (7%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L +EL+KE    EAL+E V    S L+   + +  L ++++D   E  I   + KD    
Sbjct: 705  LQKELNKEVEENEALREEVILL-SELKSLPSEVERLRKEIQDKSEELHIITSE-KD---- 758

Query: 194  VNRLAIERSHATVKVKELREQ-AETAEQVAQSRVSEQKARTEFLQAKVAEQ--EKSKAVA 250
              +L  E  H   +V+ L E+  +T + +A ++ + +    EF   K      E+   + 
Sbjct: 759  --KLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMV 816

Query: 251  XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDR--ETEIWKEL 308
                            + Q F D S+  +  E     + +  K  E  +R  E E  KE 
Sbjct: 817  LEENERMNQEIVNLSKEAQKF-DSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQ 875

Query: 309  QMTRGALLRSEEELRQSRAEK-DSFLNSLSRIAQ-GEGTESFQDKMATELLDREQKI-VK 365
               R + L++ E  +    EK    L  +  + Q  +  +  Q+ +  E    +  I   
Sbjct: 876  LENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDT 935

Query: 366  LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD---VSYPELQTEILD 422
            +   ID Q +   ++E ++ Q++  +  L+ ++    + + + ++    +  E Q +++ 
Sbjct: 936  VNMNIDTQEQLRNALE-SLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVG 994

Query: 423  LHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRI 476
            +  + + L  + T  +TA      ++E+  +   +F+ +++ + +L  +L+  I
Sbjct: 995  ID-KKQDLEAKNTQTLTADVKDNEIIEQQRK---IFS-LIQEKNELQQMLESVI 1043


>AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein.
          Length = 1208

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 83/409 (20%), Positives = 165/409 (40%), Gaps = 34/409 (8%)

Query: 20   RDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI 79
            R++E     A +T  +V VL     +T+    +   ER  + VAG   +   ++   L +
Sbjct: 617  RELEQARASAGDTR-QVEVLKKELLRTQEELKELQAERQSQEVAG--RHRDRELEKQLAV 673

Query: 80   AKIPWLDRDTMIKKIERLQKENSILQHKVD-ETSKKENEEPPCHPVQSGSYNYQVLNEEL 138
             ++   DR   +++ + LQ + ++ Q + D E + K            G     V    L
Sbjct: 674  LRVE-ADRGRELEE-QNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAV-ETTL 730

Query: 139  SKERAAREALKEVVASAESMLRVARARI---ATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
             + +   +  +  +   E  L+  R  +     +E +L+D     E  K++   LE+ +N
Sbjct: 731  RETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQ---LEEALN 787

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQE---KSKAVAXX 252
                E        + L  + E A++       EQ+     L+ +  ++E   + KA    
Sbjct: 788  ASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEE 847

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIW-KELQ 309
                          +L+   + S + +   + +  +Y      E  D  R+ + W  E +
Sbjct: 848  QKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAE 907

Query: 310  MTRGALLRSEEE---LRQ----SRAEKDSFLNSLSRIAQ--------GEGTESFQDKMAT 354
             T G L R ++E   LRQ    S+AE+D+       +AQ         E  +  QD  A 
Sbjct: 908  KTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRAR 967

Query: 355  ELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
            +L   E+K+ +L+  +DE++   + +   + +  +Q+  LR E+ + R+
Sbjct: 968  QLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERS 1016



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 74/321 (23%), Positives = 131/321 (40%), Gaps = 30/321 (9%)

Query: 104 LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVAR 163
           LQ K+DE  KK  +     P Q G      L  +L ++      L+E++   +   + + 
Sbjct: 376 LQRKLDEEVKKRQK---LEPSQVG------LERQLEEKTEECSRLQELLERRKGEAQQSN 426

Query: 164 ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ 223
             +  ++R L   +      + +  +L+  +  +        V +K+L E  E  E+V +
Sbjct: 427 KELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLE 486

Query: 224 S--RVSEQ-KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRD--RSIR 277
              RV EQ + R   L A     ++  A                  QL+ S +D  +   
Sbjct: 487 GKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHA 546

Query: 278 LVDMERRRCLEYVPC--KENEPTDRETEIWKEL-QMTRGALLRSEEELRQSRAEKDSFLN 334
           +++ ER++    V    +E E T  ET  W+ + Q  +  L  +++EL Q R EK+    
Sbjct: 547 VLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEE 606

Query: 335 SLSR---IAQGE---GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME----QTM 384
            L     + Q E      S  D    E+L +E  +++ Q+ + E +   +S E       
Sbjct: 607 ELGEKIEVLQRELEQARASAGDTRQVEVLKKE--LLRTQEELKELQAERQSQEVAGRHRD 664

Query: 385 TQYENQLAALRLEVKRLRNYD 405
            + E QLA LR+E  R R  +
Sbjct: 665 RELEKQLAVLRVEADRGRELE 685



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 39/165 (23%), Positives = 75/165 (45%), Gaps = 8/165 (4%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            +D   ++++ L+++ S L+ ++DE  +K   E     V  G      L  EL +ER+AR+
Sbjct: 962  QDDRARQLKGLEEKVSRLETELDE--EKNTVELLTDRVNRGRDQVDQLRTELMQERSARQ 1019

Query: 147  ALKEVVASAESMLRVARARIATLE------RQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
             L+    S E   +  + R+A+ E        L   +++ ++ +++ +  E+    L   
Sbjct: 1020 DLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQST 1079

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEK 245
                  KVKEL  Q E   Q    +  +   R + L+ +V E E+
Sbjct: 1080 NRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAEE 1124



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 56/287 (19%), Positives = 119/287 (41%), Gaps = 15/287 (5%)

Query: 91  IKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
           ++ ++RL  +   L+H + ET   E +    H VQ      +VL ++L + R   E + E
Sbjct: 429 LQNMKRLLDQGEDLRHGL-ETQVMELQNKLKH-VQGPEPAKEVLLKDLLETRELLEEVLE 486

Query: 151 VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE 210
                E  LR+    +  L+  LK+     E+A +     +Q V  +  +    T +++ 
Sbjct: 487 GKQRVEEQLRLRERELTALKGALKE-----EVASR-----DQEVEHVRQQYQRDTEQLRR 536

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             + A     V ++   +  A    LQ ++ E  +                     +L  
Sbjct: 537 SMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQ 596

Query: 271 FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
            R     + + E    +E +  +E E         +++++ +  LLR++EEL++ +AE+ 
Sbjct: 597 LRMEKEEMEE-ELGEKIEVLQ-RELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQ 654

Query: 331 S-FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
           S  +    R  + E   +     A    + E++ ++LQ+T+ + R++
Sbjct: 655 SQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQD 701


>AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein.
          Length = 1919

 Score = 50.8 bits (116), Expect = 1e-05
 Identities = 74/371 (19%), Positives = 151/371 (40%), Gaps = 23/371 (6%)

Query: 112 SKKENEEPPCHPVQSGSYNYQVLNE---ELSKERAAREALKEVVASAESMLRVARARIAT 168
           S +    P C    + +  +  L++   ++   R   EA ++++ +    L  + +    
Sbjct: 408 SPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRA 467

Query: 169 LERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE 228
           LE QL+  + + + A + H+D ++ V RL       + +   L    + A+Q A+    E
Sbjct: 468 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQE 527

Query: 229 Q---KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR-DRSIRLVDM-ER 283
           +   +A  E L+ +    E+ +  A                QL+     RS+   ++ E 
Sbjct: 528 REKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEV 587

Query: 284 RRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGE 343
           R  L     + +     + E+ + L       +  E  + + RAE+ S  +SLS+++   
Sbjct: 588 REALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLS--- 644

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT---QYENQLAALRLEVKR 400
              +  + +A + LD  + + +L++     +  ++  EQ  T   + + +L  LRLE + 
Sbjct: 645 ---ALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEV 701

Query: 401 LRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFAR 460
            R        +   E   E L+   Q+ TL  ER+ L    A  +  L   E+  +   R
Sbjct: 702 AR--QGLEGSLRVAEQAQEALE--QQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARR 757

Query: 461 MVRARKDLAAL 471
              A++ + AL
Sbjct: 758 --EAQRQVEAL 766



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 69/334 (20%), Positives = 145/334 (43%), Gaps = 23/334 (6%)

Query: 125  QSGSYNYQVLNEELSK-ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  S + +++ ++L + ER A+ +L+E  A+ E  L+  +       R+L+  +A+ +  
Sbjct: 862  EKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ-- 919

Query: 184  KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             +  ++ E+L+ RL  E+   + ++  L+++ +    +A+S   +Q+A +      + E 
Sbjct: 920  SQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESE--KQQALS------LKES 971

Query: 244  EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            EK+ A++                  +  RD   R  + +R           +    RE  
Sbjct: 972  EKT-ALSEKLMGTRHSLATISLEMERQKRDAQSRQ-EQDRSTVNALTSELRDLRAQREEA 1029

Query: 304  IWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQK 362
                 Q  R    R +E+ R    ++DS L     +  Q    E  +D +  ELL+ ++K
Sbjct: 1030 AAAHAQEVR----RLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRK 1085

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN--YDCYSKDVSYPELQTEI 420
            + + Q+  + QR+    + +++ +   +  ALR   + LR+      S+ +S  +L  E 
Sbjct: 1086 LRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISL-KLANE- 1143

Query: 421  LDLHLQVETLSRERTALITAAASRALMLERHERA 454
             D   ++  L   RTA+   A      L+  ER+
Sbjct: 1144 -DKEQKLALLEEARTAVGKEAGELRTGLQEVERS 1176



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 69/313 (22%), Positives = 127/313 (40%), Gaps = 20/313 (6%)

Query: 138  LSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEF-----EIAKKKHKD--L 190
            LS  +A     +E V  +E   R    ++ATLER L+ T++E      +I+K K  +  L
Sbjct: 1476 LSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKL 1535

Query: 191  EQLVNRL--AIERSHA-TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
            E    RL   ++ S + TVK++  R   E   Q ++  +S+++A+ + LQ +V   ++  
Sbjct: 1536 EGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQV 1595

Query: 248  AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKENEPTDRETEIW 305
            A +                 L    +    L D  R     L       N   D+   + 
Sbjct: 1596 ADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQ 1655

Query: 306  KEL---QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
            K L   +  R  L    +  RQ+ +E     +SL     GE  ++ + ++A   L R + 
Sbjct: 1656 KALTACEHDRQVLQERLDAARQALSEARKQSSSL-----GEQVQTLRGEVADLELQRVEA 1710

Query: 363  IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILD 422
              +LQQ  +  R+ ++     +   +      RL  +RL +       +   + + E   
Sbjct: 1711 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1770

Query: 423  LHLQVETLSRERT 435
            L L+ + ++  RT
Sbjct: 1771 LRLEKDRVALRRT 1783



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 76/366 (20%), Positives = 147/366 (40%), Gaps = 39/366 (10%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L + LSK  A  E+L +       ++       + L+ + +  + E  +A+++ + LE+L
Sbjct: 636 LQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEEL 695

Query: 194 -----VNRLAIERS-HATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKS 246
                V R  +E S     + +E  EQ     +  +S++ EQ A+ +  L  +  E E++
Sbjct: 696 RLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 755

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIW 305
           +  A                  +     +++LV  ER  R L          ++  T + 
Sbjct: 756 RREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTL----------SEEATRLR 805

Query: 306 KELQMTRGALLRSEEELRQSRAEKDSF------LNSLSRIAQGEGTESFQDKMATELLDR 359
            E +   G+L   + +L Q  A ++        L        GE     Q  +AT+    
Sbjct: 806 LEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKAS 865

Query: 360 EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR---------LEVKR--LRNYDCYS 408
             K +  Q+ +  +RE + S+ +    +E  L  L+         LE +R  L++     
Sbjct: 866 LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 925

Query: 409 KDVSYPELQTEILDLHLQVETLSRERTALITAAAS---RALMLERHERAADLFARMVRAR 465
           ++     L+ E  +L  ++  L +ER   +  A S   +AL L+  E+ A L  +++  R
Sbjct: 926 QEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTA-LSEKLMGTR 984

Query: 466 KDLAAL 471
             LA +
Sbjct: 985 HSLATI 990



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 72/311 (23%), Positives = 129/311 (41%), Gaps = 30/311 (9%)

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELS-----KERAAREALKEVVASAESML 159
            + K D  S++E +    + + S   + +   EE +     + R  +E  +++    +S L
Sbjct: 996  RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCL 1055

Query: 160  RVARARIATLERQLKDTKAEF--EIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET 217
            R A   + T  R L+D +     E+ + + K  E    R  ++R  A    + L E A+ 
Sbjct: 1056 REAE-ELRTQLRLLEDARDGLRRELLEAQRKLRESQEGR-EVQRQEAGELRRSLGEGAKE 1113

Query: 218  AEQVAQS----RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
             E + +S    R + +KA +E +  K+A ++K + +A                +      
Sbjct: 1114 REALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEV 1173

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
               RL   E RR L+ +  +        T + +EL   +G L   E   ++SR E    L
Sbjct: 1174 ERSRL---EARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRET---L 1227

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEK----SMEQTMTQYEN 389
                R+ +GE +    + M  EL   ++   KLQ+   E R  E+    S+E+     + 
Sbjct: 1228 GLRQRLLKGEAS---LEVMRQELQVAQR---KLQEQEGEFRTRERRLLGSLEEARGTEKQ 1281

Query: 390  QLAALR-LEVK 399
            QL   R LE+K
Sbjct: 1282 QLDHARGLELK 1292



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 32/146 (21%), Positives = 73/146 (50%), Gaps = 8/146 (5%)

Query: 91   IKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            +  +++LQ E  +LQ ++    +   + E     V+  +   +   + ++  R   +  +
Sbjct: 1732 LNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLE--KDRVALRRTLDKVER 1789

Query: 150  EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAI-ERSHATVKV 208
            E + S E  +R++ A    L+R L  T AE E+A+ + + ++QL  ++ + E+SH+  ++
Sbjct: 1790 EKLRSHEDTVRLS-AEKGRLDRTL--TGAELELAEAQ-RQIQQLEAQVVVLEQSHSPAQL 1845

Query: 209  KELREQAETAEQVAQSRVSEQKARTE 234
            +   +Q +   Q    R+   +A+TE
Sbjct: 1846 EVDAQQQQLELQQEVERLRSAQAQTE 1871



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 81/395 (20%), Positives = 153/395 (38%), Gaps = 27/395 (6%)

Query: 86   DRDTMIKKIERLQKENSILQHKV-----DETSKKENEEPPCHPVQSGSYNYQVLNEELSK 140
            D+  + + + +L++E S LQ +      + T  +E +E             Q L   L  
Sbjct: 653  DKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRV 712

Query: 141  ERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
               A+EAL++ + +        + ++A L RQL   + E E A+++ +   + + R A E
Sbjct: 713  AEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAARE 772

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKAR----TEFLQAKVAEQEKSKAVAXXXXXX 256
            +     +   L  Q   AE+  ++ +SE+  R     E L+  + E ++  A        
Sbjct: 773  KEALAKEHAGLAVQLVAAEREGRT-LSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQ 831

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                        ++       L  + +    + +  +E    D+E    K +Q  R A  
Sbjct: 832  LEAEGQALLLAKETLTG---ELAGLRQ----QIIATQEKASLDKELMAQKLVQAEREA-- 882

Query: 317  RSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATE-LLDREQKIVKLQQTIDEQRE 375
              +  LR+ RA  +  L  L R  +    E   ++   +  L REQ+  +L   ++ ++E
Sbjct: 883  --QASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE--ELLARLEAEKE 938

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERT 435
             E S E    Q E     L  E ++ +      K+     L  +++     + T+S E  
Sbjct: 939  -ELSEEIAALQQERDEGLLLAESEKQQALSL--KESEKTALSEKLMGTRHSLATISLEME 995

Query: 436  ALITAAASRALMLERHERAADLFARMVRARKDLAA 470
                 A SR         A     R +RA+++ AA
Sbjct: 996  RQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAA 1030


>BC114627-1|AAI14628.1|  790|Homo sapiens SLMAP protein protein.
          Length = 790

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 100/485 (20%), Positives = 192/485 (39%), Gaps = 31/485 (6%)

Query: 1   MRKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFD-----NDT 55
           +RK LIA Q    +H       ES   V  E +  VR LS +E    NTE +        
Sbjct: 236 LRKELIALQED--KHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMN 293

Query: 56  ERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKE 115
           ER    +  +A      +N   +++    +      +  ++ Q E   LQHK+DE  +KE
Sbjct: 294 ERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKE 353

Query: 116 NEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKD 175
            E      +Q+     Q  N + + ER    AL+E +     + +       + E Q + 
Sbjct: 354 QE------LQAKIEALQADN-DFTNERLT--ALQEKLIVEGHLTKAVEETKLSKENQTRA 404

Query: 176 TKAEFE--IAKKKHKDLEQLVNRLAIER--SHATVKVKELREQAETAEQVAQSRVSEQKA 231
            +++F   ++  K K  +   +    E+  +    KV  L++  + A+   +++   Q  
Sbjct: 405 KESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHL 464

Query: 232 RTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVP 291
           R E ++A+   +  SK                   Q++    + I+++  + +R      
Sbjct: 465 RKELIEAQELAR-TSKQKCFELQALLEEERKAYRNQVEE-STKQIQVLQAQLQRLHIDTE 522

Query: 292 CKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK 351
               E     T    EL   R  +L   +   +  +E+D+ + SL    +    E  + +
Sbjct: 523 NLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELERWR 582

Query: 352 MATELLDREQKIVKLQQTIDEQ-RENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
            A    + E++I  LQ +   + ++ E    +  T+ + +L  LR E   L   +C+S  
Sbjct: 583 KAAS--EYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALET-ECHSLK 639

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHE---RAADLFARMVRARKD 467
                L +E+     ++   S++++  +T+  S  L + R E   +   L  + +R   D
Sbjct: 640 RENVLLSSELQRQEKELHN-SQKQSLELTSDLS-ILQMSRKELENQVGSLKEQHLRDSAD 697

Query: 468 LAALL 472
           L  LL
Sbjct: 698 LKTLL 702



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 49/251 (19%), Positives = 99/251 (39%), Gaps = 19/251 (7%)

Query: 148 LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
           L + +  A    ++   ++ATL+R L  T+   + + +   D ++L++RL +  +     
Sbjct: 168 LSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQAC 227

Query: 208 VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
            K   E +   E +A          T     +   QEK + V                  
Sbjct: 228 SKNQTEDSLRKELIALQEDKHNYETTAKESLRRVLQEKIEVV---------RKLSEVERS 278

Query: 268 LQSFRDRSIRLVDMERR--RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQS 325
           L +  D    L +M  R    L  +  K N   +   ++  +L++  G   + EE  ++ 
Sbjct: 279 LSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEG---KQEEIQQKG 335

Query: 326 RAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE---QKIVKLQQTIDEQRENEKSMEQ 382
           +AEK    + +  + + E  +  Q K+     D +   +++  LQ+ +  +    K++E+
Sbjct: 336 QAEKKELQHKIDEMEEKE--QELQAKIEALQADNDFTNERLTALQEKLIVEGHLTKAVEE 393

Query: 383 TMTQYENQLAA 393
           T    ENQ  A
Sbjct: 394 TKLSKENQTRA 404


>AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.
          Length = 1302

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 67/307 (21%), Positives = 123/307 (40%), Gaps = 11/307 (3%)

Query: 104  LQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELS--KERAAREALKEVVASAESMLRV 161
            LQ+++DE  +K   E      Q      +     L+  K +     ++E +   +     
Sbjct: 971  LQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDE 1030

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAET-AEQ 220
            A  +   LE+ LKD + E E       D  +LV ++  + S   ++++E R  ++  +E+
Sbjct: 1031 ALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEAKVSQLEMELEEERNNSDLLSER 1090

Query: 221  VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
            +++SR   ++ R   LQ + A Q+                      +  S+R     LV 
Sbjct: 1091 ISRSREQMEQLRNGLLQERAARQDLECGKISLERQNKDLKSRIIHLE-GSYRSSKEGLVV 1149

Query: 281  MERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEEL-RQSRAEKDSFLNSLSRI 339
                R  E     E+E  DR       LQ++   L R  +EL  Q   E  S  +   ++
Sbjct: 1150 QMEARIAELEDRLESEERDRAN-----LQLSNRRLERKVKELVMQVDDEHLSLTDQKDQL 1204

Query: 340  AQGEGTESFQDKMATELLDR-EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +        Q + A E +DR E    KLQ+ ++EQ +  + ++  +   +  L   +L  
Sbjct: 1205 SLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPS 1264

Query: 399  KRLRNYD 405
            K L + D
Sbjct: 1265 KVLDDMD 1271



 Score = 48.0 bits (109), Expect = 7e-05
 Identities = 59/275 (21%), Positives = 113/275 (41%), Gaps = 11/275 (4%)

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE---LREQAETAEQV 221
            R+A L+RQ++D K +   AK+  K  E  + +L     HA  + KE    R   E   + 
Sbjct: 844  RVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEG 903

Query: 222  AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
            AQ  +S+     + L  K+ E+ + K                    ++  +     +V+ 
Sbjct: 904  AQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEA 963

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
             R   LE     +N+  + + +  +EL   +  L     E  +SR       + + R+ +
Sbjct: 964  SRTSTLEL----QNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGM-RLME 1018

Query: 342  GE--GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             E    +  QD+  T+    EQ +  L+  ++ +   +    + + Q E +++ L +E++
Sbjct: 1019 EELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEAKVSQLEMELE 1078

Query: 400  RLR-NYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
              R N D  S+ +S    Q E L   L  E  +R+
Sbjct: 1079 EERNNSDLLSERISRSREQMEQLRNGLLQERAARQ 1113



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 60/346 (17%), Positives = 146/346 (42%), Gaps = 15/346 (4%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
            E L++  + LQ ++++   K +E      ++      + L E L   R   +       +
Sbjct: 839  EELERRVAQLQRQIEDL--KGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRA 896

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E+ L  A+  ++   ++ K    + +   ++ + L +L N +  ER H    +++L  Q
Sbjct: 897  LENELEGAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKL--Q 954

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
             E A+ V  SR S  + + +  + K   ++  + +A                +L + + +
Sbjct: 955  KEMADIVEASRTSTLELQNQLDEYK---EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011

Query: 275  S-IRLVDMERRRCLEYVPCKENEPTDRET--EIWKELQMTRGALLRSEEELRQSRAEKDS 331
              +RL++ E R   +Y   ++   T R+   +  K+L+    A    +++  +   + ++
Sbjct: 1012 DGMRLMEEELR---DYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEA 1068

Query: 332  FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
             ++ L    + E   S  D ++  +    +++ +L+  + ++R   + +E      E Q 
Sbjct: 1069 KVSQLEMELEEERNNS--DLLSERISRSREQMEQLRNGLLQERAARQDLECGKISLERQN 1126

Query: 392  AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
              L+  +  L      SK+    +++  I +L  ++E+  R+R  L
Sbjct: 1127 KDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANL 1172



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 44/208 (21%), Positives = 94/208 (45%), Gaps = 13/208 (6%)

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
           QL+    ++I+      R  LE +  + NE  +  + + + L+ + G L ++ EEL Q +
Sbjct: 631 QLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVK 690

Query: 327 AEKDSFLNSLSRIAQGEGTESFQD-KMATELLDRE-----QKIVKLQQTIDEQRENEKSM 380
            E++     + R  Q + +E   +   A    DRE     +++++ +Q + +    ++  
Sbjct: 691 MEREQHQTEI-RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGR 749

Query: 381 EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLS-RERTALIT 439
           E  + + E +L AL+  +K     +  S D    +L+ E  D  LQ    S  E T  + 
Sbjct: 750 EDLLRKRERELTALKGALKE----EVSSHDQEMDKLK-EQYDAELQALRESVEEATKNVE 804

Query: 440 AAASRALMLERHERAADLFARMVRARKD 467
             ASR+   E+ +   ++  ++++   +
Sbjct: 805 VLASRSNTSEQDQAGTEMRVKLLQEENE 832



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 30/138 (21%), Positives = 66/138 (47%), Gaps = 5/138 (3%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            +D   + +++++ + S L+ +++E  ++ N +     +       + L   L +ERAAR+
Sbjct: 1056 KDDRSRLVKQMEAKVSQLEMELEE--ERNNSDLLSERISRSREQMEQLRNGLLQERAARQ 1113

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHAT 205
             L+    S E   +  ++RI  LE   + +K    +  +    + +L +RL + ER  A 
Sbjct: 1114 DLECGKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEAR--IAELEDRLESEERDRAN 1171

Query: 206  VKVKELREQAETAEQVAQ 223
            +++   R + +  E V Q
Sbjct: 1172 LQLSNRRLERKVKELVMQ 1189


>AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110kDa
            protein.
          Length = 1773

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 98/493 (19%), Positives = 196/493 (39%), Gaps = 31/493 (6%)

Query: 1    MRKNLIAQQNSLLEHYAILRDMESRAGVAAE-TLGEVRVLSNLEWKTRNTEFDNDTERLH 59
            + K L+ +++ L E   +L + ES      E T   V   ++ +     TE  +D E L 
Sbjct: 872  IEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTE--SDAEELE 929

Query: 60   RMVAGIAENLKAKINFSLEIAKIPWLDRDT-MIKKIERLQKENSILQHKVDE----TSKK 114
            R     A NL  K +  L   +    D +   IK+ E L++ N I+  K  +    + KK
Sbjct: 930  RRAQETAVNL-VKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKK 988

Query: 115  ENEEPPCHPVQSG--------SYNYQVLNEE---LSKERAAREALKEVVASAESMLRVAR 163
            E        +Q           ++ QVL E    L  +RA  E LK  V S +  + V  
Sbjct: 989  EKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLD 1048

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ 223
             ++   + +L   +     AK   ++  +L      E+ +   +VK L E+    +    
Sbjct: 1049 RQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELN 1108

Query: 224  SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX--QLQSFRDRSIRLVDM 281
             ++SE+K +   ++ ++ ++E++  V                   QL++   + ++L   
Sbjct: 1109 VQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHD 1168

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
            +R   LE       E       + +  Q  +G +   ++ L + + E +  + + SR  Q
Sbjct: 1169 QRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIER-MTAESRALQ 1227

Query: 342  G--EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
               E     ++ +  +    E+K+ + ++ +    EN K  +  + + E  +  L+ E+ 
Sbjct: 1228 SCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELD 1287

Query: 400  RLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL---ITAAASRALMLERHERAAD 456
            +L N D  S       +Q ++ +    V +L  E   +   +  A    L   +H+    
Sbjct: 1288 QL-NRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV-- 1344

Query: 457  LFARMVRARKDLA 469
            L +   R +KD++
Sbjct: 1345 LLSEQTRLQKDIS 1357



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 68/332 (20%), Positives = 141/332 (42%), Gaps = 27/332 (8%)

Query: 88   DTMIKKIERLQKENSILQHKVDETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKER 142
            + + K+ E LQ++  I + K+ +T +     +EN +     ++    N + L +EL +  
Sbjct: 1231 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN 1290

Query: 143  AAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK------KHKD-LEQLVN 195
              + +L   +++ +  L+  R  + +L+ +L + +    +AK+      KH+D L     
Sbjct: 1291 RDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQT 1350

Query: 196  RLAIERSHATVKVKELREQAETAE---QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
            RL  + S    + ++ +++ ET +   QV Q+ + E K +    +      +K +     
Sbjct: 1351 RLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEES 1410

Query: 253  XXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE-LQM 310
                          QL+    D+  +L D    + L     +E   T +E E W E L+ 
Sbjct: 1411 KLETSKVTLKEQQHQLEKELTDQKSKL-DQVLSKVL---AAEERVRTLQEEERWCESLEK 1466

Query: 311  TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDREQKIVKLQQ 368
            T     R   E  Q   EK   L +L + A     +    +++  TE    E+++  L++
Sbjct: 1467 TLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKE 1526

Query: 369  TIDEQREN-EKSM---EQTMTQYENQLAALRL 396
             +  QR   EK++   +Q  +  + ++A + L
Sbjct: 1527 ALKIQRSQLEKNLLEQKQENSCIQKEMATIEL 1558



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 77/421 (18%), Positives = 167/421 (39%), Gaps = 23/421 (5%)

Query: 67   ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
            E L   I+  L+  K    + + + + +++ Q++   +   V+    +   E      + 
Sbjct: 805  EELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHED 864

Query: 127  GSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKK 186
                 + + + L K R+       ++A AES L   + +      +  D K      +  
Sbjct: 865  IVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESD 924

Query: 187  HKDLEQLVNRLAIERSHATVKVKELREQAETAEQ--VAQSRVSEQ-----KARTEFLQAK 239
             ++LE+     A+    A  +++ L+  A+  EQ  + Q  + ++      A+    Q  
Sbjct: 925  AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 984

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRL----VDMERRRCLEYVPCKEN 295
              ++EK                      LQ  ++  + L     ++E+ +       +E 
Sbjct: 985  SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEM 1044

Query: 296  EPTDRETEIWK-ELQMTRGALLRS----EEELRQSRAEKDSFLNSLSRIAQGEGTESFQ- 349
               DR+    K EL + +G+++++    +E LR    E     N +  +       SFQ 
Sbjct: 1045 AVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK 1104

Query: 350  DKMATELLDREQKIVKLQQTIDEQREN----EKSMEQTMTQYENQLAALRLEVKRLRNYD 405
             ++  ++ +R+ ++  ++Q I+++ EN     + M +  T+ +N L  L+LE   L+   
Sbjct: 1105 GELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLK 1164

Query: 406  C-YSKDVSYPE-LQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVR 463
              + + VS  E  Q  +L+  L++E L +           +  +LER +R  +      R
Sbjct: 1165 LQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESR 1224

Query: 464  A 464
            A
Sbjct: 1225 A 1225



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 71/331 (21%), Positives = 139/331 (41%), Gaps = 29/331 (8%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           + +EL++  +A +   EV AS +       A  A LE +L    AE   A +  ++LE++
Sbjct: 121 MRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAE---ANQLKEELEKV 177

Query: 194 VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
                +E+S    ++++ R+  + A   AQ    +++  +E L AK+   +    +    
Sbjct: 178 TRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSE-LHAKLKHLQDDNNLLKQQ 236

Query: 254 XXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ---- 309
                         L    + + R+ ++ R+  L       + P+D   +   +LQ    
Sbjct: 237 LKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFS 296

Query: 310 --MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGT------ESFQDKMATELLDREQ 361
             + R    R E ++R+ + +++  L    ++A G+         + + +M  +    E 
Sbjct: 297 EILARSKWERDEAQVRERKLQEEMALQQ-EKLATGQEEFRQACERALEARMNFDKRQHEA 355

Query: 362 KIVKLQQTIDEQRENEKSME--QTMTQYENQ---------LAALRLEVKRLRNYDCYSKD 410
           +I +++  I   +EN KSME  Q +T  + Q         LA LR   K+ +  D  S++
Sbjct: 356 RIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQE 415

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAA 441
             +  L  E+  L   V T  +  TA +T A
Sbjct: 416 QVF-GLDKELKKLKKAVATSDKLATAELTIA 445


>AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110kDa
            protein.
          Length = 2325

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 98/493 (19%), Positives = 196/493 (39%), Gaps = 31/493 (6%)

Query: 1    MRKNLIAQQNSLLEHYAILRDMESRAGVAAE-TLGEVRVLSNLEWKTRNTEFDNDTERLH 59
            + K L+ +++ L E   +L + ES      E T   V   ++ +     TE  +D E L 
Sbjct: 1424 IEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTE--SDAEELE 1481

Query: 60   RMVAGIAENLKAKINFSLEIAKIPWLDRDT-MIKKIERLQKENSILQHKVDE----TSKK 114
            R     A NL  K +  L   +    D +   IK+ E L++ N I+  K  +    + KK
Sbjct: 1482 RRAQETAVNL-VKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKK 1540

Query: 115  ENEEPPCHPVQSG--------SYNYQVLNEE---LSKERAAREALKEVVASAESMLRVAR 163
            E        +Q           ++ QVL E    L  +RA  E LK  V S +  + V  
Sbjct: 1541 EKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLD 1600

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ 223
             ++   + +L   +     AK   ++  +L      E+ +   +VK L E+    +    
Sbjct: 1601 RQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELN 1660

Query: 224  SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX--QLQSFRDRSIRLVDM 281
             ++SE+K +   ++ ++ ++E++  V                   QL++   + ++L   
Sbjct: 1661 VQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHD 1720

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
            +R   LE       E       + +  Q  +G +   ++ L + + E +  + + SR  Q
Sbjct: 1721 QRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIER-MTAESRALQ 1779

Query: 342  G--EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
               E     ++ +  +    E+K+ + ++ +    EN K  +  + + E  +  L+ E+ 
Sbjct: 1780 SCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELD 1839

Query: 400  RLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL---ITAAASRALMLERHERAAD 456
            +L N D  S       +Q ++ +    V +L  E   +   +  A    L   +H+    
Sbjct: 1840 QL-NRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV-- 1896

Query: 457  LFARMVRARKDLA 469
            L +   R +KD++
Sbjct: 1897 LLSEQTRLQKDIS 1909



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 68/332 (20%), Positives = 141/332 (42%), Gaps = 27/332 (8%)

Query: 88   DTMIKKIERLQKENSILQHKVDETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKER 142
            + + K+ E LQ++  I + K+ +T +     +EN +     ++    N + L +EL +  
Sbjct: 1783 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN 1842

Query: 143  AAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK------KHKD-LEQLVN 195
              + +L   +++ +  L+  R  + +L+ +L + +    +AK+      KH+D L     
Sbjct: 1843 RDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQT 1902

Query: 196  RLAIERSHATVKVKELREQAETAE---QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
            RL  + S    + ++ +++ ET +   QV Q+ + E K +    +      +K +     
Sbjct: 1903 RLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEES 1962

Query: 253  XXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE-LQM 310
                          QL+    D+  +L D    + L     +E   T +E E W E L+ 
Sbjct: 1963 KLETSKVTLKEQQHQLEKELTDQKSKL-DQVLSKVL---AAEERVRTLQEEERWCESLEK 2018

Query: 311  TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDREQKIVKLQQ 368
            T     R   E  Q   EK   L +L + A     +    +++  TE    E+++  L++
Sbjct: 2019 TLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKE 2078

Query: 369  TIDEQREN-EKSM---EQTMTQYENQLAALRL 396
             +  QR   EK++   +Q  +  + ++A + L
Sbjct: 2079 ALKIQRSQLEKNLLEQKQENSCIQKEMATIEL 2110



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 77/421 (18%), Positives = 167/421 (39%), Gaps = 23/421 (5%)

Query: 67   ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
            E L   I+  L+  K    + + + + +++ Q++   +   V+    +   E      + 
Sbjct: 1357 EELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHED 1416

Query: 127  GSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKK 186
                 + + + L K R+       ++A AES L   + +      +  D K      +  
Sbjct: 1417 IVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESD 1476

Query: 187  HKDLEQLVNRLAIERSHATVKVKELREQAETAEQ--VAQSRVSEQ-----KARTEFLQAK 239
             ++LE+     A+    A  +++ L+  A+  EQ  + Q  + ++      A+    Q  
Sbjct: 1477 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 1536

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRL----VDMERRRCLEYVPCKEN 295
              ++EK                      LQ  ++  + L     ++E+ +       +E 
Sbjct: 1537 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEM 1596

Query: 296  EPTDRETEIWK-ELQMTRGALLRS----EEELRQSRAEKDSFLNSLSRIAQGEGTESFQ- 349
               DR+    K EL + +G+++++    +E LR    E     N +  +       SFQ 
Sbjct: 1597 AVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK 1656

Query: 350  DKMATELLDREQKIVKLQQTIDEQREN----EKSMEQTMTQYENQLAALRLEVKRLRNYD 405
             ++  ++ +R+ ++  ++Q I+++ EN     + M +  T+ +N L  L+LE   L+   
Sbjct: 1657 GELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLK 1716

Query: 406  C-YSKDVSYPE-LQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVR 463
              + + VS  E  Q  +L+  L++E L +           +  +LER +R  +      R
Sbjct: 1717 LQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESR 1776

Query: 464  A 464
            A
Sbjct: 1777 A 1777



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 71/331 (21%), Positives = 139/331 (41%), Gaps = 29/331 (8%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           + +EL++  +A +   EV AS +       A  A LE +L    AE   A +  ++LE++
Sbjct: 673 MRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAE---ANQLKEELEKV 729

Query: 194 VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
                +E+S    ++++ R+  + A   AQ    +++  +E L AK+   +    +    
Sbjct: 730 TRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSE-LHAKLKHLQDDNNLLKQQ 788

Query: 254 XXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ---- 309
                         L    + + R+ ++ R+  L       + P+D   +   +LQ    
Sbjct: 789 LKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFS 848

Query: 310 --MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGT------ESFQDKMATELLDREQ 361
             + R    R E ++R+ + +++  L    ++A G+         + + +M  +    E 
Sbjct: 849 EILARSKWERDEAQVRERKLQEEMALQQ-EKLATGQEEFRQACERALEARMNFDKRQHEA 907

Query: 362 KIVKLQQTIDEQRENEKSME--QTMTQYENQ---------LAALRLEVKRLRNYDCYSKD 410
           +I +++  I   +EN KSME  Q +T  + Q         LA LR   K+ +  D  S++
Sbjct: 908 RIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQE 967

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAA 441
             +  L  E+  L   V T  +  TA +T A
Sbjct: 968 QVF-GLDKELKKLKKAVATSDKLATAELTIA 997



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 64/343 (18%), Positives = 143/343 (41%), Gaps = 35/343 (10%)

Query: 156 ESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQA 215
           E  +  A+ R++ L  +++  + +   A ++ K LE+ +    I  +   +  K+L  + 
Sbjct: 443 EKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRL 502

Query: 216 ETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDR 274
           +   ++ Q  +  +    +  Q    +Q++ K +                 + Q S +++
Sbjct: 503 QLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQ 562

Query: 275 SIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL--QMTRGALLRSE------------- 319
            + +++ + ++ LE    +      +ETE  K+L  Q+T G +  +E             
Sbjct: 563 QLDIMNKQYQQ-LESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGL 621

Query: 320 -EELRQSRAEKDSFLNSLSRIAQGEGT--------ESFQDKMATELLDRE---QKIVKLQ 367
            E L   + +     N   ++   + T        E  +D++    +D E   +++ +L+
Sbjct: 622 QEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELE 681

Query: 368 QTIDEQRENEKSMEQT---MTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
             + EQ E   S++QT   ++ YE +L A RL + R    +   +++      T++    
Sbjct: 682 SALQEQHEVNASLQQTQGDLSAYEAELEA-RLNL-RDAEANQLKEELEKVTRLTQLEQSA 739

Query: 425 LQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKD 467
           LQ E L +ER AL  A        E+ +  ++L A++   + D
Sbjct: 740 LQAE-LEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDD 781



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 58/290 (20%), Positives = 112/290 (38%), Gaps = 38/290 (13%)

Query: 156 ESMLRVARARIATLERQLKDTKAEFEIAKKKH-KDLEQLVNRLAIERSHATVKVKELREQ 214
           E+  R +   +  LER L+    E E  K K  + LE++ N+  + +S        L+E+
Sbjct: 262 EAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKS--------LKEE 313

Query: 215 AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR-D 273
           A   +Q  +   S+   + E L+ K  E  ++                    +L  ++ D
Sbjct: 314 AMLQKQSCEELKSDLNTKNELLKQKTIELTRA-----------CQKQYELEQELAFYKID 362

Query: 274 RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
                ++       E     +  P   ++   + +  T   ++ S + ++  + E D  L
Sbjct: 363 AKFEPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQL 422

Query: 334 NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAA 393
            +     +G         + T+L D+E+KI   Q  + E  +  +  EQ + +   +   
Sbjct: 423 RNDHMNLRGH------TPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQ 476

Query: 394 LRLEVKRLRNYDCYSKDVSYPE----------LQTEILDLHLQVETLSRE 433
           L  E  +L+      KD+ Y +          L+ E LDL LQ+E   +E
Sbjct: 477 LE-EAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQE 525


>AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein.
          Length = 1793

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 98/493 (19%), Positives = 196/493 (39%), Gaps = 31/493 (6%)

Query: 1    MRKNLIAQQNSLLEHYAILRDMESRAGVAAE-TLGEVRVLSNLEWKTRNTEFDNDTERLH 59
            + K L+ +++ L E   +L + ES      E T   V   ++ +     TE  +D E L 
Sbjct: 892  IEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTE--SDAEELE 949

Query: 60   RMVAGIAENLKAKINFSLEIAKIPWLDRDT-MIKKIERLQKENSILQHKVDE----TSKK 114
            R     A NL  K +  L   +    D +   IK+ E L++ N I+  K  +    + KK
Sbjct: 950  RRAQETAVNL-VKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKK 1008

Query: 115  ENEEPPCHPVQSG--------SYNYQVLNEE---LSKERAAREALKEVVASAESMLRVAR 163
            E        +Q           ++ QVL E    L  +RA  E LK  V S +  + V  
Sbjct: 1009 EKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLD 1068

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ 223
             ++   + +L   +     AK   ++  +L      E+ +   +VK L E+    +    
Sbjct: 1069 RQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELN 1128

Query: 224  SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX--QLQSFRDRSIRLVDM 281
             ++SE+K +   ++ ++ ++E++  V                   QL++   + ++L   
Sbjct: 1129 VQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHD 1188

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
            +R   LE       E       + +  Q  +G +   ++ L + + E +  + + SR  Q
Sbjct: 1189 QRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIER-MTAESRALQ 1247

Query: 342  G--EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
               E     ++ +  +    E+K+ + ++ +    EN K  +  + + E  +  L+ E+ 
Sbjct: 1248 SCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELD 1307

Query: 400  RLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL---ITAAASRALMLERHERAAD 456
            +L N D  S       +Q ++ +    V +L  E   +   +  A    L   +H+    
Sbjct: 1308 QL-NRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV-- 1364

Query: 457  LFARMVRARKDLA 469
            L +   R +KD++
Sbjct: 1365 LLSEQTRLQKDIS 1377



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 68/332 (20%), Positives = 141/332 (42%), Gaps = 27/332 (8%)

Query: 88   DTMIKKIERLQKENSILQHKVDETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKER 142
            + + K+ E LQ++  I + K+ +T +     +EN +     ++    N + L +EL +  
Sbjct: 1251 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN 1310

Query: 143  AAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK------KHKD-LEQLVN 195
              + +L   +++ +  L+  R  + +L+ +L + +    +AK+      KH+D L     
Sbjct: 1311 RDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQT 1370

Query: 196  RLAIERSHATVKVKELREQAETAE---QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
            RL  + S    + ++ +++ ET +   QV Q+ + E K +    +      +K +     
Sbjct: 1371 RLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEES 1430

Query: 253  XXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE-LQM 310
                          QL+    D+  +L D    + L     +E   T +E E W E L+ 
Sbjct: 1431 KLETSKVTLKEQQHQLEKELTDQKSKL-DQVLSKVL---AAEERVRTLQEEERWCESLEK 1486

Query: 311  TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDREQKIVKLQQ 368
            T     R   E  Q   EK   L +L + A     +    +++  TE    E+++  L++
Sbjct: 1487 TLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKE 1546

Query: 369  TIDEQREN-EKSM---EQTMTQYENQLAALRL 396
             +  QR   EK++   +Q  +  + ++A + L
Sbjct: 1547 ALKIQRSQLEKNLLEQKQENSCIQKEMATIEL 1578



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 77/421 (18%), Positives = 167/421 (39%), Gaps = 23/421 (5%)

Query: 67   ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
            E L   I+  L+  K    + + + + +++ Q++   +   V+    +   E      + 
Sbjct: 825  EELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHED 884

Query: 127  GSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKK 186
                 + + + L K R+       ++A AES L   + +      +  D K      +  
Sbjct: 885  IVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESD 944

Query: 187  HKDLEQLVNRLAIERSHATVKVKELREQAETAEQ--VAQSRVSEQ-----KARTEFLQAK 239
             ++LE+     A+    A  +++ L+  A+  EQ  + Q  + ++      A+    Q  
Sbjct: 945  AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 1004

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRL----VDMERRRCLEYVPCKEN 295
              ++EK                      LQ  ++  + L     ++E+ +       +E 
Sbjct: 1005 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEM 1064

Query: 296  EPTDRETEIWK-ELQMTRGALLRS----EEELRQSRAEKDSFLNSLSRIAQGEGTESFQ- 349
               DR+    K EL + +G+++++    +E LR    E     N +  +       SFQ 
Sbjct: 1065 AVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK 1124

Query: 350  DKMATELLDREQKIVKLQQTIDEQREN----EKSMEQTMTQYENQLAALRLEVKRLRNYD 405
             ++  ++ +R+ ++  ++Q I+++ EN     + M +  T+ +N L  L+LE   L+   
Sbjct: 1125 GELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLK 1184

Query: 406  C-YSKDVSYPE-LQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVR 463
              + + VS  E  Q  +L+  L++E L +           +  +LER +R  +      R
Sbjct: 1185 LQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESR 1244

Query: 464  A 464
            A
Sbjct: 1245 A 1245



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 71/331 (21%), Positives = 139/331 (41%), Gaps = 29/331 (8%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           + +EL++  +A +   EV AS +       A  A LE +L    AE   A +  ++LE++
Sbjct: 147 MRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAE---ANQLKEELEKV 203

Query: 194 VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
                +E+S    ++++ R+  + A   AQ    +++  +E L AK+   +    +    
Sbjct: 204 TRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSE-LHAKLKHLQDDNNLLKQQ 262

Query: 254 XXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ---- 309
                         L    + + R+ ++ R+  L       + P+D   +   +LQ    
Sbjct: 263 LKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFS 322

Query: 310 --MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGT------ESFQDKMATELLDREQ 361
             + R    R E ++R+ + +++  L    ++A G+         + + +M  +    E 
Sbjct: 323 EILARSKWERDEAQVRERKLQEEMALQQ-EKLATGQEEFRQACERALEARMNFDKRQHEA 381

Query: 362 KIVKLQQTIDEQRENEKSME--QTMTQYENQ---------LAALRLEVKRLRNYDCYSKD 410
           +I +++  I   +EN KSME  Q +T  + Q         LA LR   K+ +  D  S++
Sbjct: 382 RIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQE 441

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAA 441
             +  L  E+  L   V T  +  TA +T A
Sbjct: 442 QVF-GLDKELKKLKKAVATSDKLATAELTIA 471


>AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein.
          Length = 2325

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 98/493 (19%), Positives = 196/493 (39%), Gaps = 31/493 (6%)

Query: 1    MRKNLIAQQNSLLEHYAILRDMESRAGVAAE-TLGEVRVLSNLEWKTRNTEFDNDTERLH 59
            + K L+ +++ L E   +L + ES      E T   V   ++ +     TE  +D E L 
Sbjct: 1424 IEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTE--SDAEELE 1481

Query: 60   RMVAGIAENLKAKINFSLEIAKIPWLDRDT-MIKKIERLQKENSILQHKVDE----TSKK 114
            R     A NL  K +  L   +    D +   IK+ E L++ N I+  K  +    + KK
Sbjct: 1482 RRAQETAVNL-VKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKK 1540

Query: 115  ENEEPPCHPVQSG--------SYNYQVLNEE---LSKERAAREALKEVVASAESMLRVAR 163
            E        +Q           ++ QVL E    L  +RA  E LK  V S +  + V  
Sbjct: 1541 EKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLD 1600

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ 223
             ++   + +L   +     AK   ++  +L      E+ +   +VK L E+    +    
Sbjct: 1601 RQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELN 1660

Query: 224  SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX--QLQSFRDRSIRLVDM 281
             ++SE+K +   ++ ++ ++E++  V                   QL++   + ++L   
Sbjct: 1661 VQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHD 1720

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
            +R   LE       E       + +  Q  +G +   ++ L + + E +  + + SR  Q
Sbjct: 1721 QRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIER-MTAESRALQ 1779

Query: 342  G--EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
               E     ++ +  +    E+K+ + ++ +    EN K  +  + + E  +  L+ E+ 
Sbjct: 1780 SCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELD 1839

Query: 400  RLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL---ITAAASRALMLERHERAAD 456
            +L N D  S       +Q ++ +    V +L  E   +   +  A    L   +H+    
Sbjct: 1840 QL-NRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV-- 1896

Query: 457  LFARMVRARKDLA 469
            L +   R +KD++
Sbjct: 1897 LLSEQTRLQKDIS 1909



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 68/332 (20%), Positives = 141/332 (42%), Gaps = 27/332 (8%)

Query: 88   DTMIKKIERLQKENSILQHKVDETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKER 142
            + + K+ E LQ++  I + K+ +T +     +EN +     ++    N + L +EL +  
Sbjct: 1783 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN 1842

Query: 143  AAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK------KHKD-LEQLVN 195
              + +L   +++ +  L+  R  + +L+ +L + +    +AK+      KH+D L     
Sbjct: 1843 RDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQT 1902

Query: 196  RLAIERSHATVKVKELREQAETAE---QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
            RL  + S    + ++ +++ ET +   QV Q+ + E K +    +      +K +     
Sbjct: 1903 RLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEES 1962

Query: 253  XXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE-LQM 310
                          QL+    D+  +L D    + L     +E   T +E E W E L+ 
Sbjct: 1963 KLETSKVTLKEQQHQLEKELTDQKSKL-DQVLSKVL---AAEERVRTLQEEERWCESLEK 2018

Query: 311  TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDREQKIVKLQQ 368
            T     R   E  Q   EK   L +L + A     +    +++  TE    E+++  L++
Sbjct: 2019 TLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKE 2078

Query: 369  TIDEQREN-EKSM---EQTMTQYENQLAALRL 396
             +  QR   EK++   +Q  +  + ++A + L
Sbjct: 2079 ALKIQRSQLEKNLLEQKQENSCIQKEMATIEL 2110



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 77/421 (18%), Positives = 167/421 (39%), Gaps = 23/421 (5%)

Query: 67   ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
            E L   I+  L+  K    + + + + +++ Q++   +   V+    +   E      + 
Sbjct: 1357 EELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHED 1416

Query: 127  GSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKK 186
                 + + + L K R+       ++A AES L   + +      +  D K      +  
Sbjct: 1417 IVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESD 1476

Query: 187  HKDLEQLVNRLAIERSHATVKVKELREQAETAEQ--VAQSRVSEQ-----KARTEFLQAK 239
             ++LE+     A+    A  +++ L+  A+  EQ  + Q  + ++      A+    Q  
Sbjct: 1477 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 1536

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRL----VDMERRRCLEYVPCKEN 295
              ++EK                      LQ  ++  + L     ++E+ +       +E 
Sbjct: 1537 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEM 1596

Query: 296  EPTDRETEIWK-ELQMTRGALLRS----EEELRQSRAEKDSFLNSLSRIAQGEGTESFQ- 349
               DR+    K EL + +G+++++    +E LR    E     N +  +       SFQ 
Sbjct: 1597 AVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK 1656

Query: 350  DKMATELLDREQKIVKLQQTIDEQREN----EKSMEQTMTQYENQLAALRLEVKRLRNYD 405
             ++  ++ +R+ ++  ++Q I+++ EN     + M +  T+ +N L  L+LE   L+   
Sbjct: 1657 GELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLK 1716

Query: 406  C-YSKDVSYPE-LQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVR 463
              + + VS  E  Q  +L+  L++E L +           +  +LER +R  +      R
Sbjct: 1717 LQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESR 1776

Query: 464  A 464
            A
Sbjct: 1777 A 1777



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 71/331 (21%), Positives = 139/331 (41%), Gaps = 29/331 (8%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           + +EL++  +A +   EV AS +       A  A LE +L    AE   A +  ++LE++
Sbjct: 673 MRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAE---ANQLKEELEKV 729

Query: 194 VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
                +E+S    ++++ R+  + A   AQ    +++  +E L AK+   +    +    
Sbjct: 730 TRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSE-LHAKLKHLQDDNNLLKQQ 788

Query: 254 XXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ---- 309
                         L    + + R+ ++ R+  L       + P+D   +   +LQ    
Sbjct: 789 LKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFS 848

Query: 310 --MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGT------ESFQDKMATELLDREQ 361
             + R    R E ++R+ + +++  L    ++A G+         + + +M  +    E 
Sbjct: 849 EILARSKWERDEAQVRERKLQEEMALQQ-EKLATGQEEFRQACERALEARMNFDKRQHEA 907

Query: 362 KIVKLQQTIDEQRENEKSME--QTMTQYENQ---------LAALRLEVKRLRNYDCYSKD 410
           +I +++  I   +EN KSME  Q +T  + Q         LA LR   K+ +  D  S++
Sbjct: 908 RIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQE 967

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAA 441
             +  L  E+  L   V T  +  TA +T A
Sbjct: 968 QVF-GLDKELKKLKKAVATSDKLATAELTIA 997



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 64/343 (18%), Positives = 143/343 (41%), Gaps = 35/343 (10%)

Query: 156 ESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQA 215
           E  +  A+ R++ L  +++  + +   A ++ K LE+ +    I  +   +  K+L  + 
Sbjct: 443 EKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRL 502

Query: 216 ETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDR 274
           +   ++ Q  +  +    +  Q    +Q++ K +                 + Q S +++
Sbjct: 503 QLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQ 562

Query: 275 SIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL--QMTRGALLRSE------------- 319
            + +++ + ++ LE    +      +ETE  K+L  Q+T G +  +E             
Sbjct: 563 QLDIMNKQYQQ-LESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGL 621

Query: 320 -EELRQSRAEKDSFLNSLSRIAQGEGT--------ESFQDKMATELLDRE---QKIVKLQ 367
            E L   + +     N   ++   + T        E  +D++    +D E   +++ +L+
Sbjct: 622 QEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELE 681

Query: 368 QTIDEQRENEKSMEQT---MTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
             + EQ E   S++QT   ++ YE +L A RL + R    +   +++      T++    
Sbjct: 682 SALQEQHEVNASLQQTQGDLSAYEAELEA-RLNL-RDAEANQLKEELEKVTRLTQLEQSA 739

Query: 425 LQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKD 467
           LQ E L +ER AL  A        E+ +  ++L A++   + D
Sbjct: 740 LQAE-LEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDD 781



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 58/290 (20%), Positives = 112/290 (38%), Gaps = 38/290 (13%)

Query: 156 ESMLRVARARIATLERQLKDTKAEFEIAKKKH-KDLEQLVNRLAIERSHATVKVKELREQ 214
           E+  R +   +  LER L+    E E  K K  + LE++ N+  + +S        L+E+
Sbjct: 262 EAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKS--------LKEE 313

Query: 215 AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR-D 273
           A   +Q  +   S+   + E L+ K  E  ++                    +L  ++ D
Sbjct: 314 AMLQKQSCEELKSDLNTKNELLKQKTIELTRA-----------CQKQYELEQELAFYKID 362

Query: 274 RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
                ++       E     +  P   ++   + +  T   ++ S + ++  + E D  L
Sbjct: 363 AKFEPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDEQL 422

Query: 334 NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAA 393
            +     +G         + T+L D+E+KI   Q  + E  +  +  EQ + +   +   
Sbjct: 423 RNDHMNLRGH------TPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQ 476

Query: 394 LRLEVKRLRNYDCYSKDVSYPE----------LQTEILDLHLQVETLSRE 433
           L  E  +L+      KD+ Y +          L+ E LDL LQ+E   +E
Sbjct: 477 LE-EAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQE 525


>AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparatus
           protein 1 variant protein.
          Length = 1585

 Score = 50.4 bits (115), Expect = 1e-05
 Identities = 69/331 (20%), Positives = 132/331 (39%), Gaps = 24/331 (7%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +RD  +K++E L+KE +     + +  +  NE       Q+     Q    ELS++    
Sbjct: 82  ERDAALKQLEALEKEKAAKLEILQQQLQVANEARDS--AQTSVTQAQREKAELSRKV--- 136

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHA 204
           E L+  V +A      A+A++A LE QL+  + +    ++  ++ +QL  +L A++ S  
Sbjct: 137 EELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLK 196

Query: 205 TVK--VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
             K  ++E + +A  A +  Q  +SE KA T  L     EQ K +               
Sbjct: 197 VTKGSLEEEKRRAADALEEQQRCISELKAETRSL----VEQHKRERKELEEERAGRKGLE 252

Query: 263 XXXXQLQSFRDRSIRLVDMERRRCL--EYVPCKENEPTDRETEIWKEL-------QMTRG 313
               QL         ++  E    +  ++    E E   +E   W+E        +   G
Sbjct: 253 ARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYG 312

Query: 314 ALLRSEEELRQSRAEK--DSFLNSLSRIAQGEGTESFQ-DKMATELLDREQKIVKLQQTI 370
           A+ + +    +   EK       +  ++A  E     Q  +   EL +    + +  Q +
Sbjct: 313 AMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQV 372

Query: 371 DEQRENEKSMEQTMTQYENQLAALRLEVKRL 401
            E+    + +   ++  + ++AA   EV RL
Sbjct: 373 QEKEVRAQKLADDLSTLQEKMAATSKEVARL 403



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 65/309 (21%), Positives = 132/309 (42%), Gaps = 17/309 (5%)

Query: 136 EELSKERAA-REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
           E+L KE AA RE  ++          + + ++ TL+ + +  + E + AK+K   +E   
Sbjct: 288 EQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESH- 346

Query: 195 NRLAIERSHATVKVKELREQ-AETAEQVAQSRVSEQKARTEF--LQAKVAEQEKSKAVAX 251
           + L I R     ++ EL    A   +QV +  V  QK   +   LQ K+A   K  A   
Sbjct: 347 SELQISRQQN--ELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLE 404

Query: 252 XXXXXXXXXXXXXXXQL--QSFRDRSIRLVDMERRRCLEYVPCKEN-EPTDRETE-IWKE 307
                          +L  +  R    +   +E ++  ++   +   +  +RE E +  E
Sbjct: 405 TLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNE 464

Query: 308 LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
           L+  R AL+ S+ + ++ R +++     ++R+ Q  G    Q  +A E   R +  ++LQ
Sbjct: 465 LERLRAALMESQGQQQEERGQQE---REVARLTQERGRA--QADLALEKAARAELEMRLQ 519

Query: 368 QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
             ++EQR    ++++ +     +      E+ +LR  +  ++     EL+  +  L  Q+
Sbjct: 520 NALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA-AQIKELEELRQTVKQLKEQL 578

Query: 428 ETLSRERTA 436
               +E  +
Sbjct: 579 AKKEKEHAS 587



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 96/446 (21%), Positives = 176/446 (39%), Gaps = 54/446 (12%)

Query: 53  NDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQ---HKVD 109
           N+   LH  +A   + ++ K   + ++A     D  T+ +K+    KE + L+    K  
Sbjct: 356 NELAELHANLARALQQVQEKEVRAQKLAD----DLSTLQEKMAATSKEVARLETLVRKAG 411

Query: 110 ETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA-LKEVVASAESM-LRVARARIA 167
           E  +  + E    P ++G    + L E+  ++  + +A L+ +   AE M   + R R A
Sbjct: 412 EQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAA 471

Query: 168 TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVS 227
            +E Q +         +++    E+ V RL  ER  A   +   +      E   Q+ ++
Sbjct: 472 LMESQGQQ--------QEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALN 523

Query: 228 EQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCL 287
           EQ+     LQ  +A     K                   +L+  R    +L +   ++  
Sbjct: 524 EQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEK 583

Query: 288 EYVP--------CKENEPTDRETEIWK-----------ELQMTRGALLRSEEELRQSRAE 328
           E+              EPT  + E  +           + Q    +L RS E  R SRAE
Sbjct: 584 EHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAE 643

Query: 329 KDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYE 388
           +DS L +L    QG+      ++ A EL   +  +   Q+ +   R   +   +   +++
Sbjct: 644 RDSALETL----QGQ-----LEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWK 694

Query: 389 NQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH-LQVETLSRERTALITAAASRALM 447
            Q+A  R E +R  +       +S  E +  IL+   L+ E  S+E   L+ A + ++  
Sbjct: 695 AQVARGRQEAERKNSL------ISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQK 748

Query: 448 LERHER--AADLFARMVRARKDLAAL 471
           LE   R   A+  +   RA +  +AL
Sbjct: 749 LEERLRLLQAETASNSARAAERSSAL 774



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 67/317 (21%), Positives = 131/317 (41%), Gaps = 32/317 (10%)

Query: 89  TMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
           T   + E+L KE +  + + +++ ++E +       Q        L EE  K R   +  
Sbjct: 282 TAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQ-----LMTLKEECEKARQELQEA 336

Query: 149 KEVVASAESM--LRVARARI------ATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
           KE VA  ES   L+++R +       A L R L+  + +   A+K   DL  L  ++A  
Sbjct: 337 KEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAAT 396

Query: 201 RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXX 260
            S    +++ L  +A   ++ A   + ++ AR    Q +  E+++ +             
Sbjct: 397 -SKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAME 455

Query: 261 XXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEE 320
                 + +   +   RL    R   +E    ++ E   +E E+ + L   RG   R++ 
Sbjct: 456 R-----EAEQMGNELERL----RAALMESQGQQQEERGQQEREVAR-LTQERG---RAQA 502

Query: 321 ELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDRE---QKIVKLQQTIDEQRE 375
           +L   +A +      L      +  E  + Q+ +A  L ++E   Q++ KL+     Q +
Sbjct: 503 DLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIK 562

Query: 376 NEKSMEQTMTQYENQLA 392
             + + QT+ Q + QLA
Sbjct: 563 ELEELRQTVKQLKEQLA 579



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 31/160 (19%), Positives = 72/160 (45%), Gaps = 3/160 (1%)

Query: 90   MIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            ++++ +R Q+E   L  +V+E SKK  +      VQ             S++ A R  L+
Sbjct: 1003 VLEERQRFQEERQKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQR--LQ 1060

Query: 150  EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDL-EQLVNRLAIERSHATVKV 208
              +   ++ L          + Q++  K  ++  K+++++L EQL +   +++ +  ++ 
Sbjct: 1061 AQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRA 1120

Query: 209  KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
            +  R   E  +   +++ +EQ  R    Q +  E + + A
Sbjct: 1121 EAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHA 1160


>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
          Length = 1937

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 68/354 (19%), Positives = 140/354 (39%), Gaps = 18/354 (5%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 1170 REAEFQKLRR-DLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK 1228

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
               + ++S    +  A+  +  + R L+D  +E    K K ++ ++L+N L  +R+    
Sbjct: 1229 METDDLSSNAEAISKAKGNLEKMCRSLEDQVSEL---KTKEEEQQRLINDLTAQRARLQT 1285

Query: 207  KVKELREQAETAEQVAQSRVSEQKART---EFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            +  E   Q +  + +       ++A T   E L+ ++ E+ K+K                
Sbjct: 1286 EAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDL 1345

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
               Q +  ++    L     +   E    +    TD   +  +EL+  +  L +  +E  
Sbjct: 1346 LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD-AIQRTEELEEAKKKLAQRLQEAE 1404

Query: 324  QSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
            +     ++   SL +  Q       Q+++   +LD E+          +QR  +K + + 
Sbjct: 1405 EHVEAVNAKCASLEKTKQ-----RLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEW 1459

Query: 384  MTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
              +YE   A L    K  R+    ++      +  E LD   Q+ETL RE   L
Sbjct: 1460 KQKYEETQAELEASQKESRSLS--TELFKVKNVYEESLD---QLETLRRENKNL 1508



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 59/296 (19%), Positives = 127/296 (42%), Gaps = 20/296 (6%)

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +K ++ SAE+        +AT++ + + TK E   ++ K K+LE+ +  L  E++   ++
Sbjct: 839  IKPLLKSAET-----EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQ 893

Query: 208  VK----ELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            V+     L +  E  EQ+ ++++ + +A+ + +  +  E+E+  A               
Sbjct: 894  VQSEADSLADAEERCEQLIKNKI-QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 952

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-L 322
                +    + ++  V+ E+      V     E    +  I K L   + AL  + ++ L
Sbjct: 953  LKKDIDDL-ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK-LSKEKKALQETHQQTL 1010

Query: 323  RQSRAEKDSFLNSLSRI-----AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENE 377
               +AE+D  +N L++       Q +  E   ++     +D E+   KL+  +   +E+ 
Sbjct: 1011 DDLQAEEDK-VNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQEST 1069

Query: 378  KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
              ME    Q + +L     E+  L +     +     +LQ +I +L  ++E L  E
Sbjct: 1070 MDMENDKQQLDEKLEKKEFEISNLIS-KIEDEQAVEIQLQKKIKELQARIEELGEE 1124



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 5/108 (4%)

Query: 145  REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            +E LKE +A  E    + +A I  L   L+ T+   +IA+++  D  + V  L  + +  
Sbjct: 1667 QEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 1726

Query: 205  TVKVKELRE-----QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
                K+L       Q+E  E + +SR +E+KA+     A +  +E  K
Sbjct: 1727 INTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKK 1774



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 79/426 (18%), Positives = 178/426 (41%), Gaps = 38/426 (8%)

Query: 56   ERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDET---- 111
            ER  +++    + L+AKI    E A+        +  K  +L+ E S L+  +D+     
Sbjct: 906  ERCEQLIKNKIQ-LEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTL 964

Query: 112  SKKENEEPPC-HPVQSGSYNYQVLNEELSKERAAREALKEV-------VASAESMLRVAR 163
            +K E E+    + V++ +     L+E ++K    ++AL+E        + + E  + +  
Sbjct: 965  AKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILT 1024

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE---RSHATVKVKELREQAETAEQ 220
                 LE+Q+ D +   E  KK   DLE+   +L  +      +T+ ++  ++Q +   +
Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLE 1084

Query: 221  VAQSRVSEQKARTEFLQA-KVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
              +  +S   ++ E  QA ++  Q+K K +                 + ++ + RS    
Sbjct: 1085 KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS---- 1140

Query: 280  DMERRRCLEYVPCKENEPTDRETEIWKELQMTRGA-LLRSEEELRQSRAEKDSFLNSLSR 338
            D+ R   LE +  +  E     T    EL   R A   +   +L ++  + ++ + +L +
Sbjct: 1141 DLSRE--LEEI-SERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK 1197

Query: 339  IAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
                       D MA EL ++   + +++Q +++++   K     ++     ++  +  +
Sbjct: 1198 --------KHADSMA-ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNL 1248

Query: 399  KRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLF 458
            +++    C S +    EL+T+  +    +  L+ +R  L T A   +  L+  +      
Sbjct: 1249 EKM----CRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQL 1304

Query: 459  ARMVRA 464
            +R  +A
Sbjct: 1305 SRSKQA 1310



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 46/252 (18%), Positives = 102/252 (40%), Gaps = 11/252 (4%)

Query: 207  KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX 266
            K+K L + AET +++A  +   QK + E  +++   +E  + +                 
Sbjct: 838  KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMV-TLLKEKNDLQLQVQS 896

Query: 267  QLQSFRDRSIRLVDMERRRCLEYVPCKE-NEPTDRETEIWKELQMTRGALLRSEEELRQS 325
            +  S  D   R   + + +       KE  E  + E EI  EL   +  L   E+E  + 
Sbjct: 897  EADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKL---EDECSEL 953

Query: 326  RAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTM 384
            + + D    +L+++  +   TE+    +  E+   ++ I KL +   E++  +++ +QT+
Sbjct: 954  KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSK---EKKALQETHQQTL 1010

Query: 385  TQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASR 444
               + +   + +  K     +    D+    L+ E   L + +E   R+    +  A   
Sbjct: 1011 DDLQAEEDKVNILTKAKTKLEQQVDDLE-GSLEQE-KKLRMDLERAKRKLEGDLKLAQES 1068

Query: 445  ALMLERHERAAD 456
             + +E  ++  D
Sbjct: 1069 TMDMENDKQQLD 1080



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 55/254 (21%), Positives = 114/254 (44%), Gaps = 19/254 (7%)

Query: 2    RKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRM 61
            R NL+  Q  + E +A L   E    +A + L +      L   T+NT   N  ++L   
Sbjct: 1680 RANLL--QAEIEELWATLEQTERSRKIAEQELLDASERVQL-LHTQNTSLINTKKKLEND 1736

Query: 62   VAGIAENLKAKINFSL---EIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEE 118
            V+ +   ++  I  S    E AK    D   M +++++ Q  ++ L+ ++ +  ++  ++
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE-RMKKNLEQTVKD 1795

Query: 119  PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKA 178
                  ++     +   +++ K  A    L+  V + +     A   +   ER++K+   
Sbjct: 1796 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTY 1855

Query: 179  EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE-QKARTEFLQ 237
            + E  +K    L+ LV++L         KVK  + QAE AE+ + + +S+ +K + E  +
Sbjct: 1856 QTEEDRKNVLRLQDLVDKLQ-------AKVKSYKRQAEEAEEQSNANLSKFRKLQHELEE 1908

Query: 238  AK----VAEQEKSK 247
            A+    +AE + +K
Sbjct: 1909 AEERAHIAESQVNK 1922


>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
          Length = 2115

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 68/317 (21%), Positives = 130/317 (41%), Gaps = 15/317 (4%)

Query: 136 EELSKERAAR--------EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKH 187
           E L KE+AA+        +   E   SA++ +  A+   A L R++++ +A  E A+++ 
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ 666

Query: 188 KDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
            + +  V  L ++      K  E    A+  +Q+ Q ++   K   +  +  + E+++  
Sbjct: 667 HEAQAQVAELELQLRSEQQKATEKERVAQEKDQL-QEQLQALKESLKVTKGSLEEEKRRA 725

Query: 248 AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKENEPTDRETEIW 305
           A A                 L     R  + ++ ER  R+ LE    +  E    ETE+ 
Sbjct: 726 ADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVL 785

Query: 306 K-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES--FQDKMATELLDREQK 362
           + EL     A   +E E  Q   E  ++        Q E      FQ+++ T   + E+ 
Sbjct: 786 RRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKA 845

Query: 363 IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILD 422
             +LQ+  ++    E   E  +++ +N+LA L   + R        K+V   +L  ++  
Sbjct: 846 RQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQ-QVQEKEVRAQKLADDLST 904

Query: 423 LHLQVETLSRERTALIT 439
           L  ++   S+E   L T
Sbjct: 905 LQEKMAATSKEVARLET 921



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 65/309 (21%), Positives = 132/309 (42%), Gaps = 17/309 (5%)

Query: 136  EELSKERAA-REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            E+L KE AA RE  ++          + + ++ TL+ + +  + E + AK+K   +E   
Sbjct: 804  EQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESH- 862

Query: 195  NRLAIERSHATVKVKELREQ-AETAEQVAQSRVSEQKARTEF--LQAKVAEQEKSKAVAX 251
            + L I R     ++ EL    A   +QV +  V  QK   +   LQ K+A   K  A   
Sbjct: 863  SELQISRQQN--ELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLE 920

Query: 252  XXXXXXXXXXXXXXXQL--QSFRDRSIRLVDMERRRCLEYVPCKEN-EPTDRETE-IWKE 307
                           +L  +  R    +   +E ++  ++   +   +  +RE E +  E
Sbjct: 921  TLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNE 980

Query: 308  LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
            L+  R AL+ S+ + ++ R +++     ++R+ Q  G    Q  +A E   R +  ++LQ
Sbjct: 981  LERLRAALMESQGQQQEERGQQE---REVARLTQERGRA--QADLALEKAARAELEMRLQ 1035

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
              ++EQR    ++++ +     +      E+ +LR  +  ++     EL+  +  L  Q+
Sbjct: 1036 NALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA-AQIKELEELRQTVKQLKEQL 1094

Query: 428  ETLSRERTA 436
                +E  +
Sbjct: 1095 AKKEKEHAS 1103



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 82/406 (20%), Positives = 159/406 (39%), Gaps = 31/406 (7%)

Query: 67  ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
           E+L  +++ +L+  +    ++  M +KI +L +EN  L  K+ E +         H  Q 
Sbjct: 286 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFAS--------HLQQL 337

Query: 127 GSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKK 186
                  LNE   +   A +   E  A  E  L  A      LE + +  + +     + 
Sbjct: 338 ----QDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKL---SQL 390

Query: 187 HKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
            + L QL +    E+      V +L    + A  +A +  ++ +AR E L+ +  +QE  
Sbjct: 391 EEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANN-TQLQARVEMLETERGQQEAK 449

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
                                LQS    SI  +   +    +         T +   +  
Sbjct: 450 LLAERGHFEEEKQQLSSLITDLQS----SISNLSQAKEELEQASQAHGARLTAQVASLTS 505

Query: 307 ELQMTRGALLRSEEE---LRQSRAEKDSFL-NSLSRIAQ-GEGTESFQDKMATELLDREQ 361
           EL      + + ++E   L+Q   EK + L  +L +  Q  +G     +++++ L  +EQ
Sbjct: 506 ELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ 565

Query: 362 KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEIL 421
           ++ ++ +  +  R++    +Q  T  E + A+LR     L+  +   K+ +    + EIL
Sbjct: 566 QLKEVAEKQEATRQDH--AQQLATAAEEREASLRERDAALKQLEALEKEKA---AKLEIL 620

Query: 422 DLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKD 467
              LQV   +R+        A R    E   +  +L A +  AR++
Sbjct: 621 QQQLQVANEARDSAQTSVTQAQRE-KAELSRKVEELQACVETARQE 665



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 78/400 (19%), Positives = 154/400 (38%), Gaps = 32/400 (8%)

Query: 97  LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAE 156
           L+++N ILQ K+ +  +  ++     P + G     VL  E  K+ AA       +A+  
Sbjct: 376 LEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAA------TLAANN 429

Query: 157 SMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAE 216
           + L+   AR+  LE +    +A+    +   ++ +Q ++ L  +   +   + + +E+ E
Sbjct: 430 TQLQ---ARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELE 486

Query: 217 TAEQVAQSRVSEQKA----RTEFLQAKVAEQEKS----KAVAXXXXXXXXXXXXXXXXQL 268
            A Q   +R++ Q A        L A + +Q++     K  A                  
Sbjct: 487 QASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQAS 546

Query: 269 QSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIW--------KELQM-TRGALLRSE 319
           Q  R +  +L    +++  +     E +   R+            +E  +  R A L+  
Sbjct: 547 QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL 606

Query: 320 EELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA---TELLDREQKIVKLQQTIDEQREN 376
           E L + +A K   L    ++A  E  +S Q  +     E  +  +K+ +LQ  ++  R+ 
Sbjct: 607 EALEKEKAAKLEILQQQLQVA-NEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665

Query: 377 EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE-RT 435
           +   +  + + E QL + + +    +      KD    +LQ     L +   +L  E R 
Sbjct: 666 QHEAQAQVAELELQLRSEQQKATE-KERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR 724

Query: 436 ALITAAASRALMLERHERAADLFARMVRARKDLAALLDGR 475
           A       +  + E       L  +  R RK+L     GR
Sbjct: 725 AADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGR 764



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 96/446 (21%), Positives = 176/446 (39%), Gaps = 54/446 (12%)

Query: 53   NDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQ---HKVD 109
            N+   LH  +A   + ++ K   + ++A     D  T+ +K+    KE + L+    K  
Sbjct: 872  NELAELHANLARALQQVQEKEVRAQKLAD----DLSTLQEKMAATSKEVARLETLVRKAG 927

Query: 110  ETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA-LKEVVASAESM-LRVARARIA 167
            E  +  + E    P ++G    + L E+  ++  + +A L+ +   AE M   + R R A
Sbjct: 928  EQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAA 987

Query: 168  TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVS 227
             +E Q +         +++    E+ V RL  ER  A   +   +      E   Q+ ++
Sbjct: 988  LMESQGQQ--------QEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALN 1039

Query: 228  EQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCL 287
            EQ+     LQ  +A     K                   +L+  R    +L +   ++  
Sbjct: 1040 EQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEK 1099

Query: 288  EYVP--------CKENEPTDRETEIWK-----------ELQMTRGALLRSEEELRQSRAE 328
            E+              EPT  + E  +           + Q    +L RS E  R SRAE
Sbjct: 1100 EHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAE 1159

Query: 329  KDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYE 388
            +DS L +L    QG+      ++ A EL   +  +   Q+ +   R   +   +   +++
Sbjct: 1160 RDSALETL----QGQ-----LEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWK 1210

Query: 389  NQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH-LQVETLSRERTALITAAASRALM 447
             Q+A  R E +R  +       +S  E +  IL+   L+ E  S+E   L+ A + ++  
Sbjct: 1211 AQVARGRQEAERKNSL------ISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQK 1264

Query: 448  LERHER--AADLFARMVRARKDLAAL 471
            LE   R   A+  +   RA +  +AL
Sbjct: 1265 LEERLRLLQAETASNSARAAERSSAL 1290



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 67/317 (21%), Positives = 131/317 (41%), Gaps = 32/317 (10%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
            T   + E+L KE +  + + +++ ++E +       Q        L EE  K R   +  
Sbjct: 798  TAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQ-----LMTLKEECEKARQELQEA 852

Query: 149  KEVVASAESM--LRVARARI------ATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
            KE VA  ES   L+++R +       A L R L+  + +   A+K   DL  L  ++A  
Sbjct: 853  KEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAAT 912

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXX 260
             S    +++ L  +A   ++ A   + ++ AR    Q +  E+++ +             
Sbjct: 913  -SKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAME 971

Query: 261  XXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEE 320
                  + +   +   RL    R   +E    ++ E   +E E+ + L   RG   R++ 
Sbjct: 972  R-----EAEQMGNELERL----RAALMESQGQQQEERGQQEREVAR-LTQERG---RAQA 1018

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDRE---QKIVKLQQTIDEQRE 375
            +L   +A +      L      +  E  + Q+ +A  L ++E   Q++ KL+     Q +
Sbjct: 1019 DLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIK 1078

Query: 376  NEKSMEQTMTQYENQLA 392
              + + QT+ Q + QLA
Sbjct: 1079 ELEELRQTVKQLKEQLA 1095


>AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein
           protein.
          Length = 2121

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 68/317 (21%), Positives = 130/317 (41%), Gaps = 15/317 (4%)

Query: 136 EELSKERAAR--------EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKH 187
           E L KE+AA+        +   E   SA++ +  A+   A L R++++ +A  E A+++ 
Sbjct: 613 EALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ 672

Query: 188 KDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
            + +  V  L ++      K  E    A+  +Q+ Q ++   K   +  +  + E+++  
Sbjct: 673 HEAQAQVAELELQLRSEQQKATEKERVAQEKDQL-QEQLQALKESLKVTKGSLEEEKRRA 731

Query: 248 AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKENEPTDRETEIW 305
           A A                 L     R  + ++ ER  R+ LE    +  E    ETE+ 
Sbjct: 732 ADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVL 791

Query: 306 K-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES--FQDKMATELLDREQK 362
           + EL     A   +E E  Q   E  ++        Q E      FQ+++ T   + E+ 
Sbjct: 792 RRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKA 851

Query: 363 IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILD 422
             +LQ+  ++    E   E  +++ +N+LA L   + R        K+V   +L  ++  
Sbjct: 852 RQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQ-QVQEKEVRAQKLADDLST 910

Query: 423 LHLQVETLSRERTALIT 439
           L  ++   S+E   L T
Sbjct: 911 LQEKMAATSKEVARLET 927



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 65/309 (21%), Positives = 132/309 (42%), Gaps = 17/309 (5%)

Query: 136  EELSKERAA-REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            E+L KE AA RE  ++          + + ++ TL+ + +  + E + AK+K   +E   
Sbjct: 810  EQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESH- 868

Query: 195  NRLAIERSHATVKVKELREQ-AETAEQVAQSRVSEQKARTEF--LQAKVAEQEKSKAVAX 251
            + L I R     ++ EL    A   +QV +  V  QK   +   LQ K+A   K  A   
Sbjct: 869  SELQISRQQN--ELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLE 926

Query: 252  XXXXXXXXXXXXXXXQL--QSFRDRSIRLVDMERRRCLEYVPCKEN-EPTDRETE-IWKE 307
                           +L  +  R    +   +E ++  ++   +   +  +RE E +  E
Sbjct: 927  TLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNE 986

Query: 308  LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
            L+  R AL+ S+ + ++ R +++     ++R+ Q  G    Q  +A E   R +  ++LQ
Sbjct: 987  LERLRAALMESQGQQQEERGQQE---REVARLTQERGRA--QADLALEKAARAELEMRLQ 1041

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
              ++EQR    ++++ +     +      E+ +LR  +  ++     EL+  +  L  Q+
Sbjct: 1042 NALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA-AQIKELEELRQTVKQLKEQL 1100

Query: 428  ETLSRERTA 436
                +E  +
Sbjct: 1101 AKKEKEHAS 1109



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 82/406 (20%), Positives = 159/406 (39%), Gaps = 31/406 (7%)

Query: 67  ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
           E+L  +++ +L+  +    ++  M +KI +L +EN  L  K+ E +         H  Q 
Sbjct: 292 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFAS--------HLQQL 343

Query: 127 GSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKK 186
                  LNE   +   A +   E  A  E  L  A      LE + +  + +     + 
Sbjct: 344 ----QDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKL---SQL 396

Query: 187 HKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
            + L QL +    E+      V +L    + A  +A +  ++ +AR E L+ +  +QE  
Sbjct: 397 EEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANN-TQLQARVEMLETERGQQEAK 455

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
                                LQS    SI  +   +    +         T +   +  
Sbjct: 456 LLAERGHFEEEKQQLSSLITDLQS----SISNLSQAKEELEQASQAHGARLTAQVASLTS 511

Query: 307 ELQMTRGALLRSEEE---LRQSRAEKDSFL-NSLSRIAQ-GEGTESFQDKMATELLDREQ 361
           EL      + + ++E   L+Q   EK + L  +L +  Q  +G     +++++ L  +EQ
Sbjct: 512 ELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ 571

Query: 362 KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEIL 421
           ++ ++ +  +  R++    +Q  T  E + A+LR     L+  +   K+ +    + EIL
Sbjct: 572 QLKEVAEKQEATRQDH--AQQLATAAEEREASLRERDAALKQLEALEKEKA---AKLEIL 626

Query: 422 DLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKD 467
              LQV   +R+        A R    E   +  +L A +  AR++
Sbjct: 627 QQQLQVANEARDSAQTSVTQAQRE-KAELSRKVEELQACVETARQE 671



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 78/400 (19%), Positives = 154/400 (38%), Gaps = 32/400 (8%)

Query: 97  LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAE 156
           L+++N ILQ K+ +  +  ++     P + G     VL  E  K+ AA       +A+  
Sbjct: 382 LEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAA------TLAANN 435

Query: 157 SMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAE 216
           + L+   AR+  LE +    +A+    +   ++ +Q ++ L  +   +   + + +E+ E
Sbjct: 436 TQLQ---ARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELE 492

Query: 217 TAEQVAQSRVSEQKA----RTEFLQAKVAEQEKS----KAVAXXXXXXXXXXXXXXXXQL 268
            A Q   +R++ Q A        L A + +Q++     K  A                  
Sbjct: 493 QASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQAS 552

Query: 269 QSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIW--------KELQM-TRGALLRSE 319
           Q  R +  +L    +++  +     E +   R+            +E  +  R A L+  
Sbjct: 553 QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL 612

Query: 320 EELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA---TELLDREQKIVKLQQTIDEQREN 376
           E L + +A K   L    ++A  E  +S Q  +     E  +  +K+ +LQ  ++  R+ 
Sbjct: 613 EALEKEKAAKLEILQQQLQVA-NEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 671

Query: 377 EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE-RT 435
           +   +  + + E QL + + +    +      KD    +LQ     L +   +L  E R 
Sbjct: 672 QHEAQAQVAELELQLRSEQQKATE-KERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR 730

Query: 436 ALITAAASRALMLERHERAADLFARMVRARKDLAALLDGR 475
           A       +  + E       L  +  R RK+L     GR
Sbjct: 731 AADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGR 770



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 96/446 (21%), Positives = 176/446 (39%), Gaps = 54/446 (12%)

Query: 53   NDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQ---HKVD 109
            N+   LH  +A   + ++ K   + ++A     D  T+ +K+    KE + L+    K  
Sbjct: 878  NELAELHANLARALQQVQEKEVRAQKLAD----DLSTLQEKMAATSKEVARLETLVRKAG 933

Query: 110  ETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA-LKEVVASAESM-LRVARARIA 167
            E  +  + E    P ++G    + L E+  ++  + +A L+ +   AE M   + R R A
Sbjct: 934  EQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAA 993

Query: 168  TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVS 227
             +E Q +         +++    E+ V RL  ER  A   +   +      E   Q+ ++
Sbjct: 994  LMESQGQQ--------QEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALN 1045

Query: 228  EQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCL 287
            EQ+     LQ  +A     K                   +L+  R    +L +   ++  
Sbjct: 1046 EQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEK 1105

Query: 288  EYVP--------CKENEPTDRETEIWK-----------ELQMTRGALLRSEEELRQSRAE 328
            E+              EPT  + E  +           + Q    +L RS E  R SRAE
Sbjct: 1106 EHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAE 1165

Query: 329  KDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYE 388
            +DS L +L    QG+      ++ A EL   +  +   Q+ +   R   +   +   +++
Sbjct: 1166 RDSALETL----QGQ-----LEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWK 1216

Query: 389  NQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH-LQVETLSRERTALITAAASRALM 447
             Q+A  R E +R  +       +S  E +  IL+   L+ E  S+E   L+ A + ++  
Sbjct: 1217 AQVARGRQEAERKNSL------ISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQK 1270

Query: 448  LERHER--AADLFARMVRARKDLAAL 471
            LE   R   A+  +   RA +  +AL
Sbjct: 1271 LEERLRLLQAETASNSARAAERSSAL 1296



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 67/317 (21%), Positives = 131/317 (41%), Gaps = 32/317 (10%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
            T   + E+L KE +  + + +++ ++E +       Q        L EE  K R   +  
Sbjct: 804  TAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQ-----LMTLKEECEKARQELQEA 858

Query: 149  KEVVASAESM--LRVARARI------ATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE 200
            KE VA  ES   L+++R +       A L R L+  + +   A+K   DL  L  ++A  
Sbjct: 859  KEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAAT 918

Query: 201  RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXX 260
             S    +++ L  +A   ++ A   + ++ AR    Q +  E+++ +             
Sbjct: 919  -SKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAME 977

Query: 261  XXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEE 320
                  + +   +   RL    R   +E    ++ E   +E E+ + L   RG   R++ 
Sbjct: 978  R-----EAEQMGNELERL----RAALMESQGQQQEERGQQEREVAR-LTQERG---RAQA 1024

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDRE---QKIVKLQQTIDEQRE 375
            +L   +A +      L      +  E  + Q+ +A  L ++E   Q++ KL+     Q +
Sbjct: 1025 DLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIK 1084

Query: 376  NEKSMEQTMTQYENQLA 392
              + + QT+ Q + QLA
Sbjct: 1085 ELEELRQTVKQLKEQLA 1101


>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
            chain protein.
          Length = 1939

 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 84/444 (18%), Positives = 183/444 (41%), Gaps = 31/444 (6%)

Query: 6    IAQQNSLLE-HYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAG 64
            I QQNS +E   A+   ++ +       + E+      E +T   + +     L R +  
Sbjct: 1089 INQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAE-RTARAKVEKLRSDLSRELEE 1147

Query: 65   IAENLK---AKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPC 121
            I+E L+      +  +E+ K     R+   +K+ R   E + LQH+    + ++      
Sbjct: 1148 ISERLEEAGGATSVQIEMNK----KREAEFQKMRR-DLEEATLQHEATAAALRKKHADSV 1202

Query: 122  HPVQSGSYNYQVLNEELSKERAA-REALKEVVASAESMLRVARARIATLERQLKDTKAEF 180
              +     N Q + ++L KE++  +  L +V ++ E +++ A+A +  + R L+D   E+
Sbjct: 1203 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKVSRTLEDQANEY 1261

Query: 181  EIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE----QVAQSRVSEQKARTEFL 236
             +   K ++ ++ +N    +R+    +  EL  Q E  E    Q+ + ++S  + + E L
Sbjct: 1262 RV---KLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQ-QMEDL 1317

Query: 237  QAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENE 296
            + ++ E+ K+K                   Q +   +    L  +  +   E    +   
Sbjct: 1318 KRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY 1377

Query: 297  PTD--RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQD---- 350
             TD  + TE  +E +      L+  EE  ++   K S L       Q E  +   D    
Sbjct: 1378 ETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERS 1437

Query: 351  KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
              A   LD++Q+     + + E ++  +  +  +   + +  +L  E+ +L+N   Y + 
Sbjct: 1438 NAAAAALDKKQR--NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN--AYEES 1493

Query: 411  VSYPE-LQTEILDLHLQVETLSRE 433
            + + E  + E  +L  ++  L+ +
Sbjct: 1494 LEHLETFKRENKNLQEEISDLTEQ 1517



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 68/341 (19%), Positives = 138/341 (40%), Gaps = 26/341 (7%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L   L +E+  R  L+      E  L++ +  I  LE      +   E  KKK  D+ Q 
Sbjct: 1036 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLE---EKLKKKEFDINQQ 1092

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF------LQAKVAEQEKSK 247
             +++  E++ A    K+L+E     E++ +   +E+ AR +       L  ++ E  +  
Sbjct: 1093 NSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1152

Query: 248  AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE 307
              A                + Q  R R +    ++       +  K     D   E+ ++
Sbjct: 1153 EEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGEQ 1208

Query: 308  LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKI-VKL 366
            +   +    + E+E  + + E D   +++ +I + +      +K++  L D+  +  VKL
Sbjct: 1209 IDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKVSRTLEDQANEYRVKL 1265

Query: 367  QQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQ 426
            ++   ++  N+ + ++   Q EN   A +LE K           +SY +   ++ DL  Q
Sbjct: 1266 EEA--QRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQ---QMEDLKRQ 1320

Query: 427  VETLSRERTALITAAASRA----LMLERHERAADLFARMVR 463
            +E   + + AL  A  S      L+ E++E   +  A + R
Sbjct: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 1361



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 49/273 (17%), Positives = 113/273 (41%), Gaps = 13/273 (4%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1670

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
            + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++       K 
Sbjct: 1671 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKK 1730

Query: 249  VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                              + ++  +++ + +        E    KE + +     + K +
Sbjct: 1731 KMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELK--KEQDTSAHLERMKKNM 1788

Query: 309  QMTRGALLRSEEELRQ--SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            + T   L    +E  Q   +  K       +R+ + EG    + K   E +   +K  + 
Sbjct: 1789 EQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERR 1848

Query: 367  QQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + +  Q E +K   + + + ++ +  L+L+VK
Sbjct: 1849 IKELTYQTEEDK---KNLLRLQDLVDKLQLKVK 1878



 Score = 35.9 bits (79), Expect = 0.32
 Identities = 53/208 (25%), Positives = 98/208 (47%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            T+  ++ E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1737 TQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1795

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1796 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELEGELEA--EQKRNAESVKGMRKS 1845

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  KK    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1846 -----ERRIKELTYQTEEDKKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1893

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1894 NLSKFRKVQHELDEAEERADIAESQVNK 1921



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 10/169 (5%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
            AE  K       E  +I      +  ++ E  +K  S+LQ K D   + + E+   +  +
Sbjct: 845  AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                  Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    KK
Sbjct: 905  ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KK 954

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTE 234
               DLE  + ++  E+     KVK L E+    +++      E+KA  E
Sbjct: 955  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQE 1003



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 80/441 (18%), Positives = 168/441 (38%), Gaps = 39/441 (8%)

Query: 43   EWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS 102
            EWK +  E  ++ E   +    ++  L     F L+ A       +  ++ +E  ++EN 
Sbjct: 1457 EWKQKYEESQSELESSQKEARSLSTEL-----FKLKNAY------EESLEHLETFKRENK 1505

Query: 103  ILQHKVDETSKKENEEPP-CHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML-R 160
             LQ ++ + +++  E     H ++      +V   EL      + AL+E  AS E    +
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLEL------QSALEEAEASLEHEEGK 1559

Query: 161  VARARI------ATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
            + RA++      A +ER+L +   E E AK+ H   +++V+ L       T      R +
Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH---QRVVDSLQTSLDAET----RSRNE 1612

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
                ++  +  ++E + +        AE +K                      +++  D 
Sbjct: 1613 VLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSLLKDTQIQLDDAVRANDDL 1669

Query: 275  SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLN 334
               +  +ERR  L     +E      +TE  +  ++    L+ + E ++   ++  S +N
Sbjct: 1670 KENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELIETSERVQLLHSQNTSLIN 1727

Query: 335  SLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAA 393
               ++       +S  ++   E  + E+K  K         E  K  + T    E     
Sbjct: 1728 QKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1787

Query: 394  LRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHE- 452
            +   +K L++    ++ ++    + ++  L  +V  L  E  A     A     + + E 
Sbjct: 1788 MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSER 1847

Query: 453  RAADLFARMVRARKDLAALLD 473
            R  +L  +    +K+L  L D
Sbjct: 1848 RIKELTYQTEEDKKNLLRLQD 1868



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 22/117 (18%), Positives = 57/117 (48%), Gaps = 4/117 (3%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++AL ++    + +  ++++++  LE+Q+ D +   E  KK   DLE
Sbjct: 993  KLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVK-LEQQVDDLEGSLEQEKKVRMDLE 1051

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQVAQSR---VSEQKARTEFLQAKVAEQEK 245
            +   +L  +       + +L       E+  + +   +++Q ++ E  QA   + +K
Sbjct: 1052 RAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQK 1108


>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
            cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
            protein.
          Length = 1939

 Score = 49.2 bits (112), Expect = 3e-05
 Identities = 84/444 (18%), Positives = 183/444 (41%), Gaps = 31/444 (6%)

Query: 6    IAQQNSLLEHYAILR-DMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAG 64
            I QQNS +E   +L   ++ +       + E+      E +T   + +     L R +  
Sbjct: 1089 INQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAE-RTARAKVEKLRSDLSRELEE 1147

Query: 65   IAENLK---AKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPC 121
            I+E L+      +  +E+ K     R+   +K+ R   E + LQH+    + ++      
Sbjct: 1148 ISERLEEAGGATSVQIEMNK----KREAEFQKMRR-DLEEATLQHEATAAALRKKHADSV 1202

Query: 122  HPVQSGSYNYQVLNEELSKERAA-REALKEVVASAESMLRVARARIATLERQLKDTKAEF 180
              +     N Q + ++L KE++  +  L +V ++ E +++ A+A +  + R L+D   E+
Sbjct: 1203 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK-AKANLEKVSRTLEDQANEY 1261

Query: 181  EIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE----QVAQSRVSEQKARTEFL 236
             +   K ++ ++ +N    +R+    +  EL  Q E  E    Q+ + ++S  + + E L
Sbjct: 1262 RV---KLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQ-QMEDL 1317

Query: 237  QAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENE 296
            + ++ E+ K+K                   Q +   +    L  +  +   E    +   
Sbjct: 1318 KRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY 1377

Query: 297  PTD--RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQD---- 350
             TD  + TE  +E +      L+  EE  ++   K S L       Q E  +   D    
Sbjct: 1378 ETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERS 1437

Query: 351  KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
              A   LD++Q+     + + E ++  +  +  +   + +  +L  E+ +L+N   Y + 
Sbjct: 1438 NAAAAALDKKQR--NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKN--AYEES 1493

Query: 411  VSYPE-LQTEILDLHLQVETLSRE 433
            + + E  + E  +L  ++  L+ +
Sbjct: 1494 LEHLETFKRENKNLQEEISDLTEQ 1517



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 68/341 (19%), Positives = 137/341 (40%), Gaps = 26/341 (7%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L   L +E+  R  L+      E  L++ +  I  LE      +   E  KKK  D+ Q 
Sbjct: 1036 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLE---EKLKKKEFDINQQ 1092

Query: 194  VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF------LQAKVAEQEKSK 247
             +++  E+  A    K+L+E     E++ +   +E+ AR +       L  ++ E  +  
Sbjct: 1093 NSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1152

Query: 248  AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE 307
              A                + Q  R R +    ++       +  K     D   E+ ++
Sbjct: 1153 EEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGEQ 1208

Query: 308  LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKI-VKL 366
            +   +    + E+E  + + E D   +++ +I + +      +K++  L D+  +  VKL
Sbjct: 1209 IDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKVSRTLEDQANEYRVKL 1265

Query: 367  QQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQ 426
            ++   ++  N+ + ++   Q EN   A +LE K           +SY +   ++ DL  Q
Sbjct: 1266 EEA--QRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQ---QMEDLKRQ 1320

Query: 427  VETLSRERTALITAAASRA----LMLERHERAADLFARMVR 463
            +E   + + AL  A  S      L+ E++E   +  A + R
Sbjct: 1321 LEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 1361



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 49/273 (17%), Positives = 113/273 (41%), Gaps = 13/273 (4%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1670

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
            + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++       K 
Sbjct: 1671 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKK 1730

Query: 249  VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                              + ++  +++ + +        E    KE + +     + K +
Sbjct: 1731 KMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELK--KEQDTSAHLERMKKNM 1788

Query: 309  QMTRGALLRSEEELRQ--SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
            + T   L    +E  Q   +  K       +R+ + EG    + K   E +   +K  + 
Sbjct: 1789 EQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERR 1848

Query: 367  QQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + +  Q E +K   + + + ++ +  L+L+VK
Sbjct: 1849 IKELTYQTEEDK---KNLLRLQDLVDKLQLKVK 1878



 Score = 35.9 bits (79), Expect = 0.32
 Identities = 53/208 (25%), Positives = 98/208 (47%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            T+  ++ E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1737 TQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1795

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1796 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELEGELEA--EQKRNAESVKGMRKS 1845

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  KK    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1846 -----ERRIKELTYQTEEDKKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1893

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1894 NLSKFRKVQHELDEAEERADIAESQVNK 1921



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 10/169 (5%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
            AE  K       E  +I      +  ++ E  +K  S+LQ K D   + + E+   +  +
Sbjct: 845  AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                  Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    KK
Sbjct: 905  ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KK 954

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTE 234
               DLE  + ++  E+     KVK L E+    +++      E+KA  E
Sbjct: 955  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQE 1003



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 80/441 (18%), Positives = 168/441 (38%), Gaps = 39/441 (8%)

Query: 43   EWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS 102
            EWK +  E  ++ E   +    ++  L     F L+ A       +  ++ +E  ++EN 
Sbjct: 1457 EWKQKYEESQSELESSQKEARSLSTEL-----FKLKNAY------EESLEHLETFKRENK 1505

Query: 103  ILQHKVDETSKKENEEPP-CHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML-R 160
             LQ ++ + +++  E     H ++      +V   EL      + AL+E  AS E    +
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLEL------QSALEEAEASLEHEEGK 1559

Query: 161  VARARI------ATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
            + RA++      A +ER+L +   E E AK+ H   +++V+ L       T      R +
Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH---QRVVDSLQTSLDAET----RSRNE 1612

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
                ++  +  ++E + +        AE +K                      +++  D 
Sbjct: 1613 VLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSLLKDTQIQLDDAVRANDDL 1669

Query: 275  SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLN 334
               +  +ERR  L     +E      +TE  +  ++    L+ + E ++   ++  S +N
Sbjct: 1670 KENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELIETSERVQLLHSQNTSLIN 1727

Query: 335  SLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAA 393
               ++       +S  ++   E  + E+K  K         E  K  + T    E     
Sbjct: 1728 QKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1787

Query: 394  LRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHE- 452
            +   +K L++    ++ ++    + ++  L  +V  L  E  A     A     + + E 
Sbjct: 1788 MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSER 1847

Query: 453  RAADLFARMVRARKDLAALLD 473
            R  +L  +    +K+L  L D
Sbjct: 1848 RIKELTYQTEEDKKNLLRLQD 1868



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 21/117 (17%), Positives = 56/117 (47%), Gaps = 4/117 (3%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++AL ++    + +  ++++++  LE+Q+ D +   E  KK   DLE
Sbjct: 993  KLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVK-LEQQVDDLEGSLEQEKKVRMDLE 1051

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQVAQSR---VSEQKARTEFLQAKVAEQEK 245
            +   +L  +       + +L       E+  + +   +++Q ++ E  Q    + +K
Sbjct: 1052 RAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQK 1108


>AB058696-1|BAB47422.1| 1270|Homo sapiens KIAA1793 protein protein.
          Length = 1270

 Score = 48.8 bits (111), Expect = 4e-05
 Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 6/143 (4%)

Query: 300 RETEIW-KELQMTRGALLRSEEELRQSRAEKDSFLNSLSR---IAQGEGTESFQDKMATE 355
           ++ E++ K++Q  +G L    EE+     EK+S L  + +   +AQ E  +S +      
Sbjct: 218 QQAEVFTKQIQQLQGELRSLREEISLLEHEKESELKEIEQELHLAQAE-IQSLRQAAEDS 276

Query: 356 LLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVS-YP 414
             + E  I  LQ+ +   +   + ME+    YE ++A+LR E++   +    S  +S Y 
Sbjct: 277 ATEHESDIASLQEDLCRMQNELEDMERIRGDYEMEIASLRAEMEMKSSEPSGSLGLSDYS 336

Query: 415 ELQTEILDLHLQVETLSRERTAL 437
            LQ E+ +L  +   L+ E  AL
Sbjct: 337 GLQEELQELRERYHFLNEEYRAL 359


>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
            non-muscle protein.
          Length = 1960

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 76/347 (21%), Positives = 154/347 (44%), Gaps = 39/347 (11%)

Query: 136  EEL-SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            EEL ++  A ++ L+E+    E+ +     R   L+ + K  +   +  +++ ++ E   
Sbjct: 900  EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959

Query: 195  NRLAIERSHATVKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVA 250
             +L +E+     K+K+L E+    E    ++A+ +   +    EF      E+EKSK++A
Sbjct: 960  QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 1019

Query: 251  XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE-IWKELQ 309
                            +L++  +  I   D+E R   E    +E E T R+ E    +L 
Sbjct: 1020 ----------------KLKNKHEAMI--TDLEERLRREEKQRQELEKTRRKLEGDSTDLS 1061

Query: 310  MTRGALLRSEEELRQSRAEKDSFLN-SLSRIAQGEGTESFQDKMA-TELLDREQKIVKLQ 367
                 L     EL+   A+K+  L  +L+R+ +    E+ Q  MA  ++ + E +I +LQ
Sbjct: 1062 DQIAELQAQIAELKMQLAKKEEELQAALARVEE----EAAQKNMALKKIRELESQISELQ 1117

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE-ILDLHLQ 426
            + ++ +R +    E+       +L AL+ E++     D      +  EL+++   ++++ 
Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELE-----DTLDSTAAQQELRSKREQEVNIL 1172

Query: 427  VETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
             +TL  E     T  A    M ++H +A +  A  +   K + A L+
Sbjct: 1173 KKTLEEEAK---THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 69/357 (19%), Positives = 151/357 (42%), Gaps = 32/357 (8%)

Query: 109  DETSKKENEEPPCHPVQSGS----YNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            D  ++ E EE  C  +Q+       N Q L E+L +E +AR+ L+    + E+ L+    
Sbjct: 919  DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978

Query: 165  RIATLERQ----------LKDTKAEFEI----AKKKHKDLEQLVNR---LAIERSHATVK 207
                LE Q          L+D  AEF       ++K K L +L N+   +  +      +
Sbjct: 979  EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR 1038

Query: 208  VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
             ++ R++ E   +  +   ++   +   LQA++AE +   A                  Q
Sbjct: 1039 EEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ 1098

Query: 268  ----LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGAL---LRSEE 320
                L+  R+   ++ +++    LE      N+   ++ ++ +EL+  +  L   L S  
Sbjct: 1099 KNMALKKIRELESQISELQED--LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSM 380
              ++ R++++  +N L +  + E  ++ + ++        Q + +L + +++ +  + ++
Sbjct: 1157 AQQELRSKREQEVNILKKTLE-EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANL 1215

Query: 381  EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            E+     EN+   L  EVK L      S+     +++ ++ +L ++     R RT L
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQGKGDSEH-KRKKVEAQLQELQVKFNEGERVRTEL 1271



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 61/234 (26%), Positives = 105/234 (44%), Gaps = 35/234 (14%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLD--RDTMIKKIERLQKENS 102
            + R  E + + ER  R +A +A   K +++     A I   +  RD  IK++ +LQ +  
Sbjct: 1590 QVREMEAELEDERKQRSMA-VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648

Query: 103  ILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEEL-SKERAAREALKEVVASAE 156
                ++D+T     E     +     ++S       L EEL + ERA R+A +E    A+
Sbjct: 1649 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1708

Query: 157  SML-------------RVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRLAI 199
             +              R   ARIA LE +L++ +   E+     KK +  ++Q+   L +
Sbjct: 1709 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768

Query: 200  ERSHATVKVKELREQAETAEQVAQSRVSEQ--------KARTEFLQAKVAEQEK 245
            ERSHA  K +  R+Q E   +  + ++ E         KA    L+AK+A+ E+
Sbjct: 1769 ERSHAQ-KNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 61/291 (20%), Positives = 123/291 (42%), Gaps = 11/291 (3%)

Query: 135  NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEF-----EIAKKKHKD 189
            + +L+K+ +A E+  +            +  ++T  +Q++D K  F     E  + KH +
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH-N 1354

Query: 190  LEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
            LE+ +  L  + +    K+++     ETAE+V +    + +  ++  + KVA  +K +  
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414

Query: 250  AXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE-YVPCKENEPTDRETEIWKEL 308
                             Q QS  +   +    ++    E  +  K  E  DR     +E 
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474

Query: 309  QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQ 368
            +    +L R+ EE  + +AE +  LN   R  + E   S +D +   + + E+    L+Q
Sbjct: 1475 ETKALSLARALEEAMEQKAELER-LNKQFR-TEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532

Query: 369  TIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
             ++E +   + +E  +   E+  A LRLEV        + +D+   + Q+E
Sbjct: 1533 QVEEMKTQLEELEDELQATED--AKLRLEVNLQAMKAQFERDLQGRDEQSE 1581



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 50/313 (15%), Positives = 122/313 (38%), Gaps = 10/313 (3%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSY----NYQVLNEELSKE 141
            +D + K +  L+K    L+ +V+E   +  E E      +        N Q +  +  ++
Sbjct: 1513 KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERD 1572

Query: 142  RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
               R+   E     + ++R  R   A LE + K         KK   DL+ L   +    
Sbjct: 1573 LQGRDEQSE--EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630

Query: 202  SHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +    +K+LR+     +   +     + +R E L      ++K K++            
Sbjct: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 1690

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD-RETEIWKELQMTRGALLRSEE 320
                 + Q+ ++R     ++        +  +E    + R  ++ +EL+  +G      +
Sbjct: 1691 AAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 1750

Query: 321  ELRQSRAEKDSFLNSLS-RIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DEQRENEK 378
             L+++  + D     L+   +  +  E+ + ++  +  + + K+ +++ T+  + + +  
Sbjct: 1751 RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810

Query: 379  SMEQTMTQYENQL 391
            ++E  + Q E QL
Sbjct: 1811 ALEAKIAQLEEQL 1823



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 73/335 (21%), Positives = 137/335 (40%), Gaps = 33/335 (9%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE--TSKKENEEPPCHP 123
            AE +K K+   LE         +  +   ++L+K  + LQ ++D+         +  C+ 
Sbjct: 1383 AEEVKRKLQKDLEGLS---QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL 1439

Query: 124  VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA-RIATLERQLKDTKAEFEI 182
             +      Q+L EE  K  +A+ A +   A AE+  +  +A  +A    +  + KAE E 
Sbjct: 1440 EKKQKKFDQLLAEE--KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELER 1497

Query: 183  AKKKHK-DLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
              K+ + ++E L++     +      V EL +     EQ    +V E K + E L+ ++ 
Sbjct: 1498 LNKQFRTEMEDLMS----SKDDVGKSVHELEKSKRALEQ----QVEEMKTQLEELEDELQ 1549

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
              E +K                    LQ   ++S    + ++++ +  V   E E  D  
Sbjct: 1550 ATEDAKL---RLEVNLQAMKAQFERDLQGRDEQS----EEKKKQLVRQVREMEAELEDER 1602

Query: 302  TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
                K+  M   A  + E +L+   A  DS   + +R    +     Q +M   + + + 
Sbjct: 1603 ----KQRSMAVAARKKLEMDLKDLEAHIDSA--NKNRDEAIKQLRKLQAQMKDCMRELDD 1656

Query: 362  KIVKLQQTIDEQRENEK---SMEQTMTQYENQLAA 393
                 ++ + + +ENEK   SME  M Q + +LAA
Sbjct: 1657 TRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 1691



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 39/183 (21%), Positives = 75/183 (40%), Gaps = 11/183 (6%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKEN 101
            LE +  NTE  ND  RL +    I +     IN  L + +      +   +++ER  KE 
Sbjct: 1738 LEEEQGNTELIND--RLKKANLQIDQ-----INTDLNLERSHAQKNENARQQLERQNKEL 1790

Query: 102  SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRV 161
             +   +++ T K + +      + +       L E+L  E   R+A  + V   E  L+ 
Sbjct: 1791 KVKLQEMEGTVKSKYKAS----ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQV 221
               ++    R  +  K + + A  + K L++ +     E   A    ++L+ + E A + 
Sbjct: 1847 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATET 1906

Query: 222  AQS 224
            A +
Sbjct: 1907 ADA 1909



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 59/336 (17%), Positives = 136/336 (40%), Gaps = 24/336 (7%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EEL K R  + A +  +   E++     A    L+ QL+   AE E+      + E+L  
Sbjct: 852  EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ---AETELCA----EAEELRA 904

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXX 252
            RL  ++        +L  + E  E+  Q   +E+K      + L+ ++ E+E ++     
Sbjct: 905  RLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMER---RRCLEYVPCKENEPTDRETEIWKELQ 309
                          +     D++ +L   ++    R  E+      E  ++   + K   
Sbjct: 965  EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT-TNLTEEEEKSKSLAKLKN 1023

Query: 310  MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA---TELLDREQKIVKL 366
                 +   EE LR+   ++   L    R  +G+ T+   D++A    ++ + + ++ K 
Sbjct: 1024 KHEAMITDLEERLRREEKQRQE-LEKTRRKLEGDSTD-LSDQIAELQAQIAELKMQLAKK 1081

Query: 367  QQTIDE--QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
            ++ +     R  E++ ++ M     ++  L  ++  L+  D  S+  S  + + +  DL 
Sbjct: 1082 EEELQAALARVEEEAAQKNMAL--KKIRELESQISELQE-DLESERASRNKAEKQKRDLG 1138

Query: 425  LQVETLSRERTALITAAASRALMLERHERAADLFAR 460
             ++E L  E    + + A++  +  + E+  ++  +
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKK 1174


>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
            protein.
          Length = 1337

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 76/347 (21%), Positives = 154/347 (44%), Gaps = 39/347 (11%)

Query: 136  EEL-SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            EEL ++  A ++ L+E+    E+ +     R   L+ + K  +   +  +++ ++ E   
Sbjct: 900  EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959

Query: 195  NRLAIERSHATVKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVA 250
             +L +E+     K+K+L E+    E    ++A+ +   +    EF      E+EKSK++A
Sbjct: 960  QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 1019

Query: 251  XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE-IWKELQ 309
                            +L++  +  I   D+E R   E    +E E T R+ E    +L 
Sbjct: 1020 ----------------KLKNKHEAMI--TDLEERLRREEKQRQELEKTRRKLEGDSTDLS 1061

Query: 310  MTRGALLRSEEELRQSRAEKDSFLN-SLSRIAQGEGTESFQDKMA-TELLDREQKIVKLQ 367
                 L     EL+   A+K+  L  +L+R+ +    E+ Q  MA  ++ + E +I +LQ
Sbjct: 1062 DQIAELQAQIAELKMQLAKKEEELQAALARVEE----EAAQKNMALKKIRELESQISELQ 1117

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE-ILDLHLQ 426
            + ++ +R +    E+       +L AL+ E++     D      +  EL+++   ++++ 
Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELE-----DTLDSTAAQQELRSKREQEVNIL 1172

Query: 427  VETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
             +TL  E     T  A    M ++H +A +  A  +   K + A L+
Sbjct: 1173 KKTLEEEAK---THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 69/357 (19%), Positives = 151/357 (42%), Gaps = 32/357 (8%)

Query: 109  DETSKKENEEPPCHPVQSGS----YNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            D  ++ E EE  C  +Q+       N Q L E+L +E +AR+ L+    + E+ L+    
Sbjct: 919  DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978

Query: 165  RIATLERQ----------LKDTKAEFEI----AKKKHKDLEQLVNR---LAIERSHATVK 207
                LE Q          L+D  AEF       ++K K L +L N+   +  +      +
Sbjct: 979  EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR 1038

Query: 208  VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
             ++ R++ E   +  +   ++   +   LQA++AE +   A                  Q
Sbjct: 1039 EEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ 1098

Query: 268  ----LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGAL---LRSEE 320
                L+  R+   ++ +++    LE      N+   ++ ++ +EL+  +  L   L S  
Sbjct: 1099 KNMALKKIRELESQISELQED--LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSM 380
              ++ R++++  +N L +  + E  ++ + ++        Q + +L + +++ +  + ++
Sbjct: 1157 AQQELRSKREQEVNILKKTLE-EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANL 1215

Query: 381  EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            E+     EN+   L  EVK L      S+     +++ ++ +L ++     R RT L
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQGKGDSEH-KRKKVEAQLQELQVKFNEGERVRTEL 1271



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 59/336 (17%), Positives = 136/336 (40%), Gaps = 24/336 (7%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EEL K R  + A +  +   E++     A    L+ QL+   AE E+      + E+L  
Sbjct: 852  EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ---AETELCA----EAEELRA 904

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXX 252
            RL  ++        +L  + E  E+  Q   +E+K      + L+ ++ E+E ++     
Sbjct: 905  RLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMER---RRCLEYVPCKENEPTDRETEIWKELQ 309
                          +     D++ +L   ++    R  E+      E  ++   + K   
Sbjct: 965  EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT-TNLTEEEEKSKSLAKLKN 1023

Query: 310  MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA---TELLDREQKIVKL 366
                 +   EE LR+   ++   L    R  +G+ T+   D++A    ++ + + ++ K 
Sbjct: 1024 KHEAMITDLEERLRREEKQRQE-LEKTRRKLEGDSTD-LSDQIAELQAQIAELKMQLAKK 1081

Query: 367  QQTIDE--QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
            ++ +     R  E++ ++ M     ++  L  ++  L+  D  S+  S  + + +  DL 
Sbjct: 1082 EEELQAALARVEEEAAQKNMAL--KKIRELESQISELQE-DLESERASRNKAEKQKRDLG 1138

Query: 425  LQVETLSRERTALITAAASRALMLERHERAADLFAR 460
             ++E L  E    + + A++  +  + E+  ++  +
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKK 1174


>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
           myosin heavy chain (NMHC) mRNA, 3' end. ).
          Length = 1247

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 76/347 (21%), Positives = 154/347 (44%), Gaps = 39/347 (11%)

Query: 136 EEL-SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
           EEL ++  A ++ L+E+    E+ +     R   L+ + K  +   +  +++ ++ E   
Sbjct: 186 EELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESAR 245

Query: 195 NRLAIERSHATVKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVA 250
            +L +E+     K+K+L E+    E    ++A+ +   +    EF      E+EKSK++A
Sbjct: 246 QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 305

Query: 251 XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE-IWKELQ 309
                           +L++  +  I   D+E R   E    +E E T R+ E    +L 
Sbjct: 306 ----------------KLKNKHEAMI--TDLEERLRREEKQRQELEKTRRKLEGDSTDLS 347

Query: 310 MTRGALLRSEEELRQSRAEKDSFLN-SLSRIAQGEGTESFQDKMA-TELLDREQKIVKLQ 367
                L     EL+   A+K+  L  +L+R+ +    E+ Q  MA  ++ + E +I +LQ
Sbjct: 348 DQIAELQAQIAELKMQLAKKEEELQAALARVEE----EAAQKNMALKKIRELESQISELQ 403

Query: 368 QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE-ILDLHLQ 426
           + ++ +R +    E+       +L AL+ E++     D      +  EL+++   ++++ 
Sbjct: 404 EDLESERASRNKAEKQKRDLGEELEALKTELE-----DTLDSTAAQQELRSKREQEVNIL 458

Query: 427 VETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
            +TL  E     T  A    M ++H +A +  A  +   K + A L+
Sbjct: 459 KKTLEEEAK---THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 502



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 82/431 (19%), Positives = 180/431 (41%), Gaps = 35/431 (8%)

Query: 31  ETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTM 90
           E L +VR    L  + R  E +    +L      + E L+A+     E  ++    R  +
Sbjct: 138 EELVKVRE-KQLAAENRLMEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL----RARL 192

Query: 91  IKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
             K + L++    L+ +V+E  ++E  +      +    N Q L E+L +E +AR+ L+ 
Sbjct: 193 TAKKQELEEICHDLEARVEE--EEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 250

Query: 151 VVASAESMLRVARARIATLERQ----------LKDTKAEFEI----AKKKHKDLEQLVNR 196
              + E+ L+        LE Q          L+D  AEF       ++K K L +L N+
Sbjct: 251 EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNK 310

Query: 197 ---LAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              +  +      + ++ R++ E   +  +   ++   +   LQA++AE +   A     
Sbjct: 311 HEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEE 370

Query: 254 XXXXXXXXXXXXXQ----LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ 309
                        Q    L+  R+   ++ +++    LE      N+   ++ ++ +EL+
Sbjct: 371 LQAALARVEEEAAQKNMALKKIRELESQISELQED--LESERASRNKAEKQKRDLGEELE 428

Query: 310 MTRGAL---LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKL 366
             +  L   L S    ++ R++++  +N L +  + E  ++ + ++        Q + +L
Sbjct: 429 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE-EEAKTHEAQIQEMRQKHSQAVEEL 487

Query: 367 QQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQ 426
            + +++ +  + ++E+     EN+   L  EVK L      S+     +++ ++ +L ++
Sbjct: 488 AEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGGRDSEH-KRKKVEAQLQELQVK 546

Query: 427 VETLSRERTAL 437
                R RT L
Sbjct: 547 FNEGERVRTEL 557



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 56/315 (17%), Positives = 124/315 (39%), Gaps = 14/315 (4%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSY----NYQVLNEELSKE 141
            +D + K +  L+K    L+ +V+E   +  E E      +        N Q +  +  ++
Sbjct: 800  KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERD 859

Query: 142  RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
               R+   E     + ++R  R   A LE + K         KK   DL+ L   +    
Sbjct: 860  LQGRDEQSE--EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 917

Query: 202  SHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +    +K+LR+     +   +     + +R E L      ++K K++            
Sbjct: 918  KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 977

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD-RETEIWKELQMTRGALLRSEE 320
                 + Q+ ++R     ++        +  +E    + R  ++ +EL+  +G      +
Sbjct: 978  AAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 1037

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQ---TI-DEQREN 376
             L+++  + D  +N+   + +G   ++   +   E  ++E K VKLQ+   T+  + + +
Sbjct: 1038 RLKKANLQIDQ-INADLNLERGHAQKNENARQQLERQNKELK-VKLQEMEGTVKSKYKAS 1095

Query: 377  EKSMEQTMTQYENQL 391
              ++E  + Q E QL
Sbjct: 1096 ITALEAKIAQLEEQL 1110



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 60/234 (25%), Positives = 104/234 (44%), Gaps = 35/234 (14%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLD--RDTMIKKIERLQKENS 102
            + R  E + + ER  R +A +A   K +++     A I   +  RD  IK++ +LQ +  
Sbjct: 877  QVREMEAELEDERKQRSMA-VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 935

Query: 103  ILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEEL-SKERAAREALKEVVASAE 156
                ++D+T     E     +     ++S       L EEL + ERA R+A +E    A+
Sbjct: 936  DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 995

Query: 157  SML-------------RVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRLAI 199
             +              R   ARIA LE +L++ +   E+     KK +  ++Q+   L +
Sbjct: 996  EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNL 1055

Query: 200  ERSHATVKVKELREQAETAEQVAQSRVSEQ--------KARTEFLQAKVAEQEK 245
            ER HA  K +  R+Q E   +  + ++ E         KA    L+AK+A+ E+
Sbjct: 1056 ERGHAQ-KNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1108



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 73/335 (21%), Positives = 137/335 (40%), Gaps = 33/335 (9%)

Query: 66  AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE--TSKKENEEPPCHP 123
           AE +K K+   LE         +  +   ++L+K  + LQ ++D+         +  C+ 
Sbjct: 670 AEEVKRKLQKDLEGLS---QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL 726

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA-RIATLERQLKDTKAEFEI 182
            +      Q+L EE  K  +A+ A +   A AE+  +  +A  +A    +  + KAE E 
Sbjct: 727 EKKQKKFDQLLAEE--KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELER 784

Query: 183 AKKKHK-DLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
             K+ + ++E L++     +      V EL +     EQ    +V E K + E L+ ++ 
Sbjct: 785 LNKQFRTEMEDLMS----SKDDVGKSVHELEKSKRALEQ----QVEEMKTQLEELEDELQ 836

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
             E +K                    LQ   ++S    + ++++ +  V   E E  D  
Sbjct: 837 ATEDAKL---RLEVNLQAMKAQFERDLQGRDEQS----EEKKKQLVRQVREMEAELEDER 889

Query: 302 TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
               K+  M   A  + E +L+   A  DS   + +R    +     Q +M   + + + 
Sbjct: 890 ----KQRSMAVAARKKLEMDLKDLEAHIDSA--NKNRDEAIKQLRKLQAQMKDCMRELDD 943

Query: 362 KIVKLQQTIDEQRENEK---SMEQTMTQYENQLAA 393
                ++ + + +ENEK   SME  M Q + +LAA
Sbjct: 944 TRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 978



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 39/183 (21%), Positives = 75/183 (40%), Gaps = 11/183 (6%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKEN 101
            LE +  NTE  ND  RL +    I +     IN  L + +      +   +++ER  KE 
Sbjct: 1025 LEEEQGNTELIND--RLKKANLQIDQ-----INADLNLERGHAQKNENARQQLERQNKEL 1077

Query: 102  SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRV 161
             +   +++ T K + +      + +       L E+L  E   R+A  + V   E  L+ 
Sbjct: 1078 KVKLQEMEGTVKSKYKAS----ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1133

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQV 221
               ++    R  +  K + + A  + K L++ +     E   A    ++L+ + E A + 
Sbjct: 1134 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATET 1193

Query: 222  AQS 224
            A +
Sbjct: 1194 ADA 1196



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 59/336 (17%), Positives = 136/336 (40%), Gaps = 24/336 (7%)

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           EEL K R  + A +  +   E++     A    L+ QL+   AE E+      + E+L  
Sbjct: 138 EELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQ---AETELCA----EAEELRA 190

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXX 252
           RL  ++        +L  + E  E+  Q   +E+K      + L+ ++ E+E ++     
Sbjct: 191 RLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 250

Query: 253 XXXXXXXXXXXXXXQLQSFRDRSIRLVDMER---RRCLEYVPCKENEPTDRETEIWKELQ 309
                         +     D++ +L   ++    R  E+      E  ++   + K   
Sbjct: 251 EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT-TNLTEEEEKSKSLAKLKN 309

Query: 310 MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA---TELLDREQKIVKL 366
                +   EE LR+   ++   L    R  +G+ T+   D++A    ++ + + ++ K 
Sbjct: 310 KHEAMITDLEERLRREEKQRQE-LEKTRRKLEGDSTD-LSDQIAELQAQIAELKMQLAKK 367

Query: 367 QQTIDE--QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
           ++ +     R  E++ ++ M     ++  L  ++  L+  D  S+  S  + + +  DL 
Sbjct: 368 EEELQAALARVEEEAAQKNMAL--KKIRELESQISELQE-DLESERASRNKAEKQKRDLG 424

Query: 425 LQVETLSRERTALITAAASRALMLERHERAADLFAR 460
            ++E L  E    + + A++  +  + E+  ++  +
Sbjct: 425 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKK 460


>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
          Length = 1960

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 76/347 (21%), Positives = 154/347 (44%), Gaps = 39/347 (11%)

Query: 136  EEL-SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            EEL ++  A ++ L+E+    E+ +     R   L+ + K  +   +  +++ ++ E   
Sbjct: 900  EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959

Query: 195  NRLAIERSHATVKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVA 250
             +L +E+     K+K+L E+    E    ++A+ +   +    EF      E+EKSK++A
Sbjct: 960  QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 1019

Query: 251  XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE-IWKELQ 309
                            +L++  +  I   D+E R   E    +E E T R+ E    +L 
Sbjct: 1020 ----------------KLKNKHEAMI--TDLEERLRREEKQRQELEKTRRKLEGDSTDLS 1061

Query: 310  MTRGALLRSEEELRQSRAEKDSFLN-SLSRIAQGEGTESFQDKMA-TELLDREQKIVKLQ 367
                 L     EL+   A+K+  L  +L+R+ +    E+ Q  MA  ++ + E +I +LQ
Sbjct: 1062 DQIAELQAQIAELKMQLAKKEEELQAALARVEE----EAAQKNMALKKIRELESQISELQ 1117

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE-ILDLHLQ 426
            + ++ +R +    E+       +L AL+ E++     D      +  EL+++   ++++ 
Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELE-----DTLDSTAAQQELRSKREQEVNIL 1172

Query: 427  VETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
             +TL  E     T  A    M ++H +A +  A  +   K + A L+
Sbjct: 1173 KKTLEEEAK---THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 69/357 (19%), Positives = 151/357 (42%), Gaps = 32/357 (8%)

Query: 109  DETSKKENEEPPCHPVQSGS----YNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            D  ++ E EE  C  +Q+       N Q L E+L +E +AR+ L+    + E+ L+    
Sbjct: 919  DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978

Query: 165  RIATLERQ----------LKDTKAEFEI----AKKKHKDLEQLVNR---LAIERSHATVK 207
                LE Q          L+D  AEF       ++K K L +L N+   +  +      +
Sbjct: 979  EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR 1038

Query: 208  VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
             ++ R++ E   +  +   ++   +   LQA++AE +   A                  Q
Sbjct: 1039 EEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ 1098

Query: 268  ----LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGAL---LRSEE 320
                L+  R+   ++ +++    LE      N+   ++ ++ +EL+  +  L   L S  
Sbjct: 1099 KNMALKKIRELESQISELQED--LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSM 380
              ++ R++++  +N L +  + E  ++ + ++        Q + +L + +++ +  + ++
Sbjct: 1157 AQQELRSKREQEVNILKKTLE-EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANL 1215

Query: 381  EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            E+     EN+   L  EVK L      S+     +++ ++ +L ++     R RT L
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQGKGDSEH-KRKKVEAQLQELQVKFNEGERVRTEL 1271



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 61/234 (26%), Positives = 105/234 (44%), Gaps = 35/234 (14%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLD--RDTMIKKIERLQKENS 102
            + R  E + + ER  R +A +A   K +++     A I   +  RD  IK++ +LQ +  
Sbjct: 1590 QVREMEAELEDERKQRSMA-VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648

Query: 103  ILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEEL-SKERAAREALKEVVASAE 156
                ++D+T     E     +     ++S       L EEL + ERA R+A +E    A+
Sbjct: 1649 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1708

Query: 157  SML-------------RVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRLAI 199
             +              R   ARIA LE +L++ +   E+     KK +  ++Q+   L +
Sbjct: 1709 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768

Query: 200  ERSHATVKVKELREQAETAEQVAQSRVSEQ--------KARTEFLQAKVAEQEK 245
            ERSHA  K +  R+Q E   +  + ++ E         KA    L+AK+A+ E+
Sbjct: 1769 ERSHAQ-KNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 61/291 (20%), Positives = 123/291 (42%), Gaps = 11/291 (3%)

Query: 135  NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEF-----EIAKKKHKD 189
            + +L+K+ +A E+  +            +  ++T  +Q++D K  F     E  + KH +
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH-N 1354

Query: 190  LEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
            LE+ +  L  + +    K+++     ETAE+V +    + +  ++  + KVA  +K +  
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414

Query: 250  AXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE-YVPCKENEPTDRETEIWKEL 308
                             Q QS  +   +    ++    E  +  K  E  DR     +E 
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474

Query: 309  QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQ 368
            +    +L R+ EE  + +AE +  LN   R  + E   S +D +   + + E+    L+Q
Sbjct: 1475 ETKALSLARALEEAMEQKAELER-LNKQFR-TEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532

Query: 369  TIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
             ++E +   + +E  +   E+  A LRLEV        + +D+   + Q+E
Sbjct: 1533 QVEEMKTQLEELEDELQATED--AKLRLEVNLQAMKAQFERDLQGRDEQSE 1581



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 50/313 (15%), Positives = 122/313 (38%), Gaps = 10/313 (3%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSY----NYQVLNEELSKE 141
            +D + K +  L+K    L+ +V+E   +  E E      +        N Q +  +  ++
Sbjct: 1513 KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERD 1572

Query: 142  RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
               R+   E     + ++R  R   A LE + K         KK   DL+ L   +    
Sbjct: 1573 LQGRDEQSE--EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630

Query: 202  SHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +    +K+LR+     +   +     + +R E L      ++K K++            
Sbjct: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 1690

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD-RETEIWKELQMTRGALLRSEE 320
                 + Q+ ++R     ++        +  +E    + R  ++ +EL+  +G      +
Sbjct: 1691 AAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 1750

Query: 321  ELRQSRAEKDSFLNSLS-RIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DEQRENEK 378
             L+++  + D     L+   +  +  E+ + ++  +  + + K+ +++ T+  + + +  
Sbjct: 1751 RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810

Query: 379  SMEQTMTQYENQL 391
            ++E  + Q E QL
Sbjct: 1811 ALEAKIAQLEEQL 1823



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 73/335 (21%), Positives = 137/335 (40%), Gaps = 33/335 (9%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE--TSKKENEEPPCHP 123
            AE +K K+   LE         +  +   ++L+K  + LQ ++D+         +  C+ 
Sbjct: 1383 AEEVKRKLQKDLEGLS---QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL 1439

Query: 124  VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA-RIATLERQLKDTKAEFEI 182
             +      Q+L EE  K  +A+ A +   A AE+  +  +A  +A    +  + KAE E 
Sbjct: 1440 EKKQKKFDQLLAEE--KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELER 1497

Query: 183  AKKKHK-DLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
              K+ + ++E L++     +      V EL +     EQ    +V E K + E L+ ++ 
Sbjct: 1498 LNKQFRTEMEDLMS----SKDDVGKSVHELEKSKRALEQ----QVEEMKTQLEELEDELQ 1549

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
              E +K                    LQ   ++S    + ++++ +  V   E E  D  
Sbjct: 1550 ATEDAKL---RLEVNLQAMKAQFERDLQGRDEQS----EEKKKQLVRQVREMEAELEDER 1602

Query: 302  TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
                K+  M   A  + E +L+   A  DS   + +R    +     Q +M   + + + 
Sbjct: 1603 ----KQRSMAVAARKKLEMDLKDLEAHIDSA--NKNRDEAIKQLRKLQAQMKDCMRELDD 1656

Query: 362  KIVKLQQTIDEQRENEK---SMEQTMTQYENQLAA 393
                 ++ + + +ENEK   SME  M Q + +LAA
Sbjct: 1657 TRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 1691



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 39/183 (21%), Positives = 75/183 (40%), Gaps = 11/183 (6%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKEN 101
            LE +  NTE  ND  RL +    I +     IN  L + +      +   +++ER  KE 
Sbjct: 1738 LEEEQGNTELIND--RLKKANLQIDQ-----INTDLNLERSHAQKNENARQQLERQNKEL 1790

Query: 102  SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRV 161
             +   +++ T K + +      + +       L E+L  E   R+A  + V   E  L+ 
Sbjct: 1791 KVKLQEMEGTVKSKYKAS----ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQV 221
               ++    R  +  K + + A  + K L++ +     E   A    ++L+ + E A + 
Sbjct: 1847 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATET 1906

Query: 222  AQS 224
            A +
Sbjct: 1907 ADA 1909



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 59/336 (17%), Positives = 136/336 (40%), Gaps = 24/336 (7%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EEL K R  + A +  +   E++     A    L+ QL+   AE E+      + E+L  
Sbjct: 852  EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ---AETELCA----EAEELRA 904

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXX 252
            RL  ++        +L  + E  E+  Q   +E+K      + L+ ++ E+E ++     
Sbjct: 905  RLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMER---RRCLEYVPCKENEPTDRETEIWKELQ 309
                          +     D++ +L   ++    R  E+      E  ++   + K   
Sbjct: 965  EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT-TNLTEEEEKSKSLAKLKN 1023

Query: 310  MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA---TELLDREQKIVKL 366
                 +   EE LR+   ++   L    R  +G+ T+   D++A    ++ + + ++ K 
Sbjct: 1024 KHEAMITDLEERLRREEKQRQE-LEKTRRKLEGDSTD-LSDQIAELQAQIAELKMQLAKK 1081

Query: 367  QQTIDE--QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
            ++ +     R  E++ ++ M     ++  L  ++  L+  D  S+  S  + + +  DL 
Sbjct: 1082 EEELQAALARVEEEAAQKNMAL--KKIRELESQISELQE-DLESERASRNKAEKQKRDLG 1138

Query: 425  LQVETLSRERTALITAAASRALMLERHERAADLFAR 460
             ++E L  E    + + A++  +  + E+  ++  +
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKK 1174


>BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for
            IMAGE:5563109) protein.
          Length = 1374

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 76/347 (21%), Positives = 154/347 (44%), Gaps = 39/347 (11%)

Query: 136  EEL-SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            EEL ++  A ++ L+E+    E+ +     R   L+ + K  +   +  +++ ++ E   
Sbjct: 900  EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959

Query: 195  NRLAIERSHATVKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVA 250
             +L +E+     K+K+L E+    E    ++A+ +   +    EF      E+EKSK++A
Sbjct: 960  QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 1019

Query: 251  XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE-IWKELQ 309
                            +L++  +  I   D+E R   E    +E E T R+ E    +L 
Sbjct: 1020 ----------------KLKNKHEAMI--TDLEERLRREEKQRQELEKTRRKLEGDSTDLS 1061

Query: 310  MTRGALLRSEEELRQSRAEKDSFLN-SLSRIAQGEGTESFQDKMA-TELLDREQKIVKLQ 367
                 L     EL+   A+K+  L  +L+R+ +    E+ Q  MA  ++ + E +I +LQ
Sbjct: 1062 DQIAELQAQIAELKMQLAKKEEELQAALARVEE----EAAQKNMALKKIRELESQISELQ 1117

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE-ILDLHLQ 426
            + ++ +R +    E+       +L AL+ E++     D      +  EL+++   ++++ 
Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELE-----DTLDSTAAQQELRSKREQEVNIL 1172

Query: 427  VETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
             +TL  E     T  A    M ++H +A +  A  +   K + A L+
Sbjct: 1173 KKTLEEEAK---THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 69/357 (19%), Positives = 151/357 (42%), Gaps = 32/357 (8%)

Query: 109  DETSKKENEEPPCHPVQSGS----YNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            D  ++ E EE  C  +Q+       N Q L E+L +E +AR+ L+    + E+ L+    
Sbjct: 919  DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978

Query: 165  RIATLERQ----------LKDTKAEFEI----AKKKHKDLEQLVNR---LAIERSHATVK 207
                LE Q          L+D  AEF       ++K K L +L N+   +  +      +
Sbjct: 979  EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR 1038

Query: 208  VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
             ++ R++ E   +  +   ++   +   LQA++AE +   A                  Q
Sbjct: 1039 EEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ 1098

Query: 268  ----LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGAL---LRSEE 320
                L+  R+   ++ +++    LE      N+   ++ ++ +EL+  +  L   L S  
Sbjct: 1099 KNMALKKIRELESQISELQED--LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSM 380
              ++ R++++  +N L +  + E  ++ + ++        Q + +L + +++ +  + ++
Sbjct: 1157 AQQELRSKREQEVNILKKTLE-EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANL 1215

Query: 381  EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            E+     EN+   L  EVK L      S+     +++ ++ +L ++     R RT L
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQGKGDSEH-KRKKVEAQLQELQVKFNEGERVRTEL 1271



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 59/336 (17%), Positives = 136/336 (40%), Gaps = 24/336 (7%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EEL K R  + A +  +   E++     A    L+ QL+   AE E+      + E+L  
Sbjct: 852  EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ---AETELCA----EAEELRA 904

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXX 252
            RL  ++        +L  + E  E+  Q   +E+K      + L+ ++ E+E ++     
Sbjct: 905  RLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMER---RRCLEYVPCKENEPTDRETEIWKELQ 309
                          +     D++ +L   ++    R  E+      E  ++   + K   
Sbjct: 965  EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT-TNLTEEEEKSKSLAKLKN 1023

Query: 310  MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA---TELLDREQKIVKL 366
                 +   EE LR+   ++   L    R  +G+ T+   D++A    ++ + + ++ K 
Sbjct: 1024 KHEAMITDLEERLRREEKQRQE-LEKTRRKLEGDSTD-LSDQIAELQAQIAELKMQLAKK 1081

Query: 367  QQTIDE--QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
            ++ +     R  E++ ++ M     ++  L  ++  L+  D  S+  S  + + +  DL 
Sbjct: 1082 EEELQAALARVEEEAAQKNMAL--KKIRELESQISELQE-DLESERASRNKAEKQKRDLG 1138

Query: 425  LQVETLSRERTALITAAASRALMLERHERAADLFAR 460
             ++E L  E    + + A++  +  + E+  ++  +
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKK 1174


>BC007570-1|AAH07570.1|  649|Homo sapiens FBF1 protein protein.
          Length = 649

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 80/377 (21%), Positives = 165/377 (43%), Gaps = 34/377 (9%)

Query: 55  TERLHRMVAGIAENLKAKINFSLEIAKIPWLD-RDTMIKKIERLQK-ENSILQHKVDETS 112
           T +  R +A IA+    ++    E+ +   LD R    ++++RL+  ++  +      TS
Sbjct: 189 TAQHQRRLAAIAQEKDQEMERLRELQRASILDMRRDHEEQLQRLKLLKDREVDAATSATS 248

Query: 113 KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEV-VASAESMLRVARARIATLER 171
              +     H ++  S +   L+  +          +E+ +   +  LR  + R+   +R
Sbjct: 249 HTRSLNSIIHQMEKFSSSLHELSSRVEASHLTTSQERELGIRQRDEQLRALQERLGQQQR 308

Query: 172 QLKDTKAEFE--IAK------KKHKDLEQLVNRLAIERSHATVKVKELREQAE-TAEQVA 222
            +++ ++  +  I K      ++ + LEQ   R+  E+S A    + L EQ + TA+Q+A
Sbjct: 309 DMEEERSRQQEVIGKMEARLNEQSRLLEQERWRVTAEQSKAESMQRALEEQRKVTAQQMA 368

Query: 223 QSRVSEQKARTEFLQAKVAE-----QEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIR 277
             R   ++A++  L+ + +      +E+ +  A                + ++  +R+++
Sbjct: 369 MERAELERAKSALLEEQKSVMLKCGEERRRLAAEWAEFSAQQKLSKERAEREA--ERALQ 426

Query: 278 LVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLS 337
            VD +R   L  +  K+ E   R +E+  E +         E+E ++ R EK+    +  
Sbjct: 427 -VDTQREGTLISL-AKQAELKIRASELRAEEKQLAAERAALEQERQELRLEKERINATAL 484

Query: 338 RIA-QGEGTESFQDKMATELLD------REQKIVKLQQ-----TIDEQRENEKSMEQTMT 385
           R+  + E  ES   K+A+E  +      RE + V+ +Q      + +Q+E  +  EQ M 
Sbjct: 485 RVKLRAEEVESMS-KVASEKYEEGERALREAQQVQAEQQARLQAVQQQQERLRKQEQHMH 543

Query: 386 QYENQLAALRLEVKRLR 402
           Q    LA  RL++ R R
Sbjct: 544 QEHLSLAQQRLQLDRAR 560


>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
            polypeptide 9 protein.
          Length = 1960

 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 76/347 (21%), Positives = 154/347 (44%), Gaps = 39/347 (11%)

Query: 136  EEL-SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            EEL ++  A ++ L+E+    E+ +     R   L+ + K  +   +  +++ ++ E   
Sbjct: 900  EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959

Query: 195  NRLAIERSHATVKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVA 250
             +L +E+     K+K+L E+    E    ++A+ +   +    EF      E+EKSK++A
Sbjct: 960  QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLA 1019

Query: 251  XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE-IWKELQ 309
                            +L++  +  I   D+E R   E    +E E T R+ E    +L 
Sbjct: 1020 ----------------KLKNKHEAMI--TDLEERLRREEKQRQELEKTRRKLEGDSTDLS 1061

Query: 310  MTRGALLRSEEELRQSRAEKDSFLN-SLSRIAQGEGTESFQDKMA-TELLDREQKIVKLQ 367
                 L     EL+   A+K+  L  +L+R+ +    E+ Q  MA  ++ + E +I +LQ
Sbjct: 1062 DQIAELQAQIAELKMQLAKKEEELQAALARVEE----EAAQKNMALKKIRELESQISELQ 1117

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE-ILDLHLQ 426
            + ++ +R +    E+       +L AL+ E++     D      +  EL+++   ++++ 
Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELE-----DTLDSTAAQQELRSKREQEVNIL 1172

Query: 427  VETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
             +TL  E     T  A    M ++H +A +  A  +   K + A L+
Sbjct: 1173 KKTLEEEAK---THEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 69/357 (19%), Positives = 151/357 (42%), Gaps = 32/357 (8%)

Query: 109  DETSKKENEEPPCHPVQSGS----YNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            D  ++ E EE  C  +Q+       N Q L E+L +E +AR+ L+    + E+ L+    
Sbjct: 919  DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978

Query: 165  RIATLERQ----------LKDTKAEFEI----AKKKHKDLEQLVNR---LAIERSHATVK 207
                LE Q          L+D  AEF       ++K K L +L N+   +  +      +
Sbjct: 979  EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR 1038

Query: 208  VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
             ++ R++ E   +  +   ++   +   LQA++AE +   A                  Q
Sbjct: 1039 EEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ 1098

Query: 268  ----LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGAL---LRSEE 320
                L+  R+   ++ +++    LE      N+   ++ ++ +EL+  +  L   L S  
Sbjct: 1099 KNMALKKIRELESQISELQED--LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSM 380
              ++ R++++  +N L +  + E  ++ + ++        Q + +L + +++ +  + ++
Sbjct: 1157 AQQELRSKREQEVNILKKTLE-EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANL 1215

Query: 381  EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            E+     EN+   L  EVK L      S+     +++ ++ +L ++     R RT L
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQGKGDSEH-KRKKVEAQLQELQVKFNEGERVRTEL 1271



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 61/234 (26%), Positives = 105/234 (44%), Gaps = 35/234 (14%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLD--RDTMIKKIERLQKENS 102
            + R  E + + ER  R +A +A   K +++     A I   +  RD  IK++ +LQ +  
Sbjct: 1590 QVREMEAELEDERKQRSMA-VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648

Query: 103  ILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEEL-SKERAAREALKEVVASAE 156
                ++D+T     E     +     ++S       L EEL + ERA R+A +E    A+
Sbjct: 1649 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1708

Query: 157  SML-------------RVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRLAI 199
             +              R   ARIA LE +L++ +   E+     KK +  ++Q+   L +
Sbjct: 1709 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768

Query: 200  ERSHATVKVKELREQAETAEQVAQSRVSEQ--------KARTEFLQAKVAEQEK 245
            ERSHA  K +  R+Q E   +  + ++ E         KA    L+AK+A+ E+
Sbjct: 1769 ERSHAQ-KNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 61/291 (20%), Positives = 123/291 (42%), Gaps = 11/291 (3%)

Query: 135  NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEF-----EIAKKKHKD 189
            + +L+K+ +A E+  +            +  ++T  +Q++D K  F     E  + KH +
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH-N 1354

Query: 190  LEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
            LE+ +  L  + +    K+++     ETAE+V +    + +  ++  + KVA  +K +  
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414

Query: 250  AXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE-YVPCKENEPTDRETEIWKEL 308
                             Q QS  +   +    ++    E  +  K  E  DR     +E 
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474

Query: 309  QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQ 368
            +    +L R+ EE  + +AE +  LN   R  + E   S +D +   + + E+    L+Q
Sbjct: 1475 ETKALSLARALEEAMEQKAELER-LNKQFR-TEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532

Query: 369  TIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
             ++E +   + +E  +   E+  A LRLEV        + +D+   + Q+E
Sbjct: 1533 QVEEMKTQLEELEDELQATED--AKLRLEVNLQAMKAQFERDLQGRDEQSE 1581



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 50/313 (15%), Positives = 122/313 (38%), Gaps = 10/313 (3%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSY----NYQVLNEELSKE 141
            +D + K +  L+K    L+ +V+E   +  E E      +        N Q +  +  ++
Sbjct: 1513 KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERD 1572

Query: 142  RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
               R+   E     + ++R  R   A LE + K         KK   DL+ L   +    
Sbjct: 1573 LQGRDEQSE--EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630

Query: 202  SHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +    +K+LR+     +   +     + +R E L      ++K K++            
Sbjct: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 1690

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD-RETEIWKELQMTRGALLRSEE 320
                 + Q+ ++R     ++        +  +E    + R  ++ +EL+  +G      +
Sbjct: 1691 AAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 1750

Query: 321  ELRQSRAEKDSFLNSLS-RIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DEQRENEK 378
             L+++  + D     L+   +  +  E+ + ++  +  + + K+ +++ T+  + + +  
Sbjct: 1751 RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 1810

Query: 379  SMEQTMTQYENQL 391
            ++E  + Q E QL
Sbjct: 1811 ALEAKIAQLEEQL 1823



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 73/335 (21%), Positives = 137/335 (40%), Gaps = 33/335 (9%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE--TSKKENEEPPCHP 123
            AE +K K+   LE         +  +   ++L+K  + LQ ++D+         +  C+ 
Sbjct: 1383 AEEVKRKLQKDLEGLS---QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL 1439

Query: 124  VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA-RIATLERQLKDTKAEFEI 182
             +      Q+L EE  K  +A+ A +   A AE+  +  +A  +A    +  + KAE E 
Sbjct: 1440 EKKQKKFDQLLAEE--KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELER 1497

Query: 183  AKKKHK-DLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
              K+ + ++E L++     +      V EL +     EQ    +V E K + E L+ ++ 
Sbjct: 1498 LNKQFRTEMEDLMS----SKDDVGKSVHELEKSKRALEQ----QVEEMKTQLEELEDELQ 1549

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
              E +K                    LQ   ++S    + ++++ +  V   E E  D  
Sbjct: 1550 ATEDAKL---RLEVNLQAMKAQFERDLQGRDEQS----EEKKKQLVRQVREMEAELEDER 1602

Query: 302  TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
                K+  M   A  + E +L+   A  DS   + +R    +     Q +M   + + + 
Sbjct: 1603 ----KQRSMAVAARKKLEMDLKDLEAHIDSA--NKNRDEAIKQLRKLQAQMKDCMRELDD 1656

Query: 362  KIVKLQQTIDEQRENEK---SMEQTMTQYENQLAA 393
                 ++ + + +ENEK   SME  M Q + +LAA
Sbjct: 1657 TRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 1691



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 39/183 (21%), Positives = 75/183 (40%), Gaps = 11/183 (6%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKEN 101
            LE +  NTE  ND  RL +    I +     IN  L + +      +   +++ER  KE 
Sbjct: 1738 LEEEQGNTELIND--RLKKANLQIDQ-----INTDLNLERSHAQKNENARQQLERQNKEL 1790

Query: 102  SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRV 161
             +   +++ T K + +      + +       L E+L  E   R+A  + V   E  L+ 
Sbjct: 1791 KVKLQEMEGTVKSKYKAS----ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846

Query: 162  ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQV 221
               ++    R  +  K + + A  + K L++ +     E   A    ++L+ + E A + 
Sbjct: 1847 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATET 1906

Query: 222  AQS 224
            A +
Sbjct: 1907 ADA 1909



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 59/336 (17%), Positives = 136/336 (40%), Gaps = 24/336 (7%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EEL K R  + A +  +   E++     A    L+ QL+   AE E+      + E+L  
Sbjct: 852  EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ---AETELCA----EAEELRA 904

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXX 252
            RL  ++        +L  + E  E+  Q   +E+K      + L+ ++ E+E ++     
Sbjct: 905  RLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMER---RRCLEYVPCKENEPTDRETEIWKELQ 309
                          +     D++ +L   ++    R  E+      E  ++   + K   
Sbjct: 965  EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT-TNLTEEEEKSKSLAKLKN 1023

Query: 310  MTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA---TELLDREQKIVKL 366
                 +   EE LR+   ++   L    R  +G+ T+   D++A    ++ + + ++ K 
Sbjct: 1024 KHEAMITDLEERLRREEKQRQE-LEKTRRKLEGDSTD-LSDQIAELQAQIAELKMQLAKK 1081

Query: 367  QQTIDE--QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
            ++ +     R  E++ ++ M     ++  L  ++  L+  D  S+  S  + + +  DL 
Sbjct: 1082 EEELQAALARVEEEAAQKNMAL--KKIRELESQISELQE-DLESERASRNKAEKQKRDLG 1138

Query: 425  LQVETLSRERTALITAAASRALMLERHERAADLFAR 460
             ++E L  E    + + A++  +  + E+  ++  +
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKK 1174


>AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein 1
            protein.
          Length = 1820

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 74/372 (19%), Positives = 159/372 (42%), Gaps = 39/372 (10%)

Query: 65   IAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKE------NSILQHK---VDETSKKE 115
            I E  K + + S ++ +   L+++++I K+ER  KE      +S+   K   V E   KE
Sbjct: 1169 ILETQKVECSHSAKLEQ-DILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKE 1227

Query: 116  NEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKD 175
                  + +Q   +  Q+  EE    R   E LKE ++++ +  +  +A +   E    D
Sbjct: 1228 EITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYAD 1287

Query: 176  TKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQKAR 232
             K +   AKK+ K +++ V+ +  E     +K+ EL ++     Q   + Q  + + K +
Sbjct: 1288 LKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQ 1347

Query: 233  TEFLQAKVAEQEKSKAV----AXXXXXXXXXXXXXXXXQLQSFRDRSI--RLVDMER--- 283
                + + A Q+  +A                      Q Q  +D+ +  +L ++ER   
Sbjct: 1348 LNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLAT 1407

Query: 284  ------RRCLEYVPCKENEPTDRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
                   +C + +  K N+ +++E    T++  +L   +  L  SE++    R  K    
Sbjct: 1408 ELEKWKEKCND-LETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADR--KKWLE 1464

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTID----EQRENEKSMEQTMTQYEN 389
              +  I Q +  E+ ++K   +  +  ++  K Q  ++    +  E +  +++   + + 
Sbjct: 1465 EKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQ 1524

Query: 390  QLAALRLEVKRL 401
             +AAL +++K L
Sbjct: 1525 LVAALEIQLKAL 1536



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 303 EIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
           +I  EL  T+G L++++EEL++   E DS +  L    +   T++ + K    ++D+++ 
Sbjct: 719 QIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINIIDQKED 778

Query: 363 IVKLQQTIDEQREN 376
            +   Q +    EN
Sbjct: 779 TINEFQNLKSHMEN 792


>AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein 1
            protein.
          Length = 1780

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 74/372 (19%), Positives = 159/372 (42%), Gaps = 39/372 (10%)

Query: 65   IAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKE------NSILQHK---VDETSKKE 115
            I E  K + + S ++ +   L+++++I K+ER  KE      +S+   K   V E   KE
Sbjct: 1129 ILETQKVECSHSAKLEQ-DILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKE 1187

Query: 116  NEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKD 175
                  + +Q   +  Q+  EE    R   E LKE ++++ +  +  +A +   E    D
Sbjct: 1188 EITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYAD 1247

Query: 176  TKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQKAR 232
             K +   AKK+ K +++ V+ +  E     +K+ EL ++     Q   + Q  + + K +
Sbjct: 1248 LKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQ 1307

Query: 233  TEFLQAKVAEQEKSKAV----AXXXXXXXXXXXXXXXXQLQSFRDRSI--RLVDMER--- 283
                + + A Q+  +A                      Q Q  +D+ +  +L ++ER   
Sbjct: 1308 LNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLAT 1367

Query: 284  ------RRCLEYVPCKENEPTDRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
                   +C + +  K N+ +++E    T++  +L   +  L  SE++    R  K    
Sbjct: 1368 ELEKWKEKCND-LETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADR--KKWLE 1424

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTID----EQRENEKSMEQTMTQYEN 389
              +  I Q +  E+ ++K   +  +  ++  K Q  ++    +  E +  +++   + + 
Sbjct: 1425 EKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQ 1484

Query: 390  QLAALRLEVKRL 401
             +AAL +++K L
Sbjct: 1485 LVAALEIQLKAL 1496



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 303 EIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
           +I  EL  T+G L++++EEL++   E DS +  L    +   T++ + K    ++D+++ 
Sbjct: 679 QIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINIIDQKED 738

Query: 363 IVKLQQTIDEQREN 376
            +   Q +    EN
Sbjct: 739 TINEFQNLKSHMEN 752


>AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein 1
            protein.
          Length = 1780

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 74/372 (19%), Positives = 159/372 (42%), Gaps = 39/372 (10%)

Query: 65   IAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKE------NSILQHK---VDETSKKE 115
            I E  K + + S ++ +   L+++++I K+ER  KE      +S+   K   V E   KE
Sbjct: 1129 ILETQKVECSHSAKLEQ-DILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKE 1187

Query: 116  NEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKD 175
                  + +Q   +  Q+  EE    R   E LKE ++++ +  +  +A +   E    D
Sbjct: 1188 EITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYAD 1247

Query: 176  TKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQKAR 232
             K +   AKK+ K +++ V+ +  E     +K+ EL ++     Q   + Q  + + K +
Sbjct: 1248 LKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQ 1307

Query: 233  TEFLQAKVAEQEKSKAV----AXXXXXXXXXXXXXXXXQLQSFRDRSI--RLVDMER--- 283
                + + A Q+  +A                      Q Q  +D+ +  +L ++ER   
Sbjct: 1308 LNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLAT 1367

Query: 284  ------RRCLEYVPCKENEPTDRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
                   +C + +  K N+ +++E    T++  +L   +  L  SE++    R  K    
Sbjct: 1368 ELEKWKEKCND-LETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADR--KKWLE 1424

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTID----EQRENEKSMEQTMTQYEN 389
              +  I Q +  E+ ++K   +  +  ++  K Q  ++    +  E +  +++   + + 
Sbjct: 1425 EKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQ 1484

Query: 390  QLAALRLEVKRL 401
             +AAL +++K L
Sbjct: 1485 LVAALEIQLKAL 1496



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 303 EIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
           +I  EL  T+G L++++EEL++   E DS +  L    +   T++ + K    ++D+++ 
Sbjct: 679 QIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINIIDQKED 738

Query: 363 IVKLQQTIDEQREN 376
            +   Q +    EN
Sbjct: 739 TINEFQNLKSHMEN 752


>AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein 1
            protein.
          Length = 1820

 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 74/372 (19%), Positives = 159/372 (42%), Gaps = 39/372 (10%)

Query: 65   IAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKE------NSILQHK---VDETSKKE 115
            I E  K + + S ++ +   L+++++I K+ER  KE      +S+   K   V E   KE
Sbjct: 1169 ILETQKVECSHSAKLEQ-DILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKE 1227

Query: 116  NEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKD 175
                  + +Q   +  Q+  EE    R   E LKE ++++ +  +  +A +   E    D
Sbjct: 1228 EITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYAD 1287

Query: 176  TKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQKAR 232
             K +   AKK+ K +++ V+ +  E     +K+ EL ++     Q   + Q  + + K +
Sbjct: 1288 LKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQ 1347

Query: 233  TEFLQAKVAEQEKSKAV----AXXXXXXXXXXXXXXXXQLQSFRDRSI--RLVDMER--- 283
                + + A Q+  +A                      Q Q  +D+ +  +L ++ER   
Sbjct: 1348 LNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLAT 1407

Query: 284  ------RRCLEYVPCKENEPTDRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
                   +C + +  K N+ +++E    T++  +L   +  L  SE++    R  K    
Sbjct: 1408 ELEKWKEKCND-LETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADR--KKWLE 1464

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTID----EQRENEKSMEQTMTQYEN 389
              +  I Q +  E+ ++K   +  +  ++  K Q  ++    +  E +  +++   + + 
Sbjct: 1465 EKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQ 1524

Query: 390  QLAALRLEVKRL 401
             +AAL +++K L
Sbjct: 1525 LVAALEIQLKAL 1536



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 303 EIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
           +I  EL  T+G L++++EEL++   E DS +  L    +   T++ + K    ++D+++ 
Sbjct: 719 QIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINIIDQKED 778

Query: 363 IVKLQQTIDEQREN 376
            +   Q +    EN
Sbjct: 779 TINEFQNLKSHMEN 792


>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
          Length = 2663

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 70/337 (20%), Positives = 142/337 (42%), Gaps = 32/337 (9%)

Query: 86   DRDTMIKKIER-LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
            +++T I  I++ L+  N  LQ+K+ E  +KE +            N + ++E        
Sbjct: 1502 EKETEISTIQKQLEAINDKLQNKIQEIYEKEEQ-----------LNIKQISEVQENVNEL 1550

Query: 145  REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            ++  KE   + +S L+   +++  L  +L++++ E +I  K+ ++++++   L IER   
Sbjct: 1551 KQ-FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQL 1609

Query: 205  TVKVKE----LREQAETAEQ----VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
                KE    ++E  E   Q     A +   E+    E L+ +   Q+ +          
Sbjct: 1610 KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIR 1669

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN--EPTDRETEIWKELQMTRGA 314
                      +++S       L  +E    +E    KEN  E   R+ E  +EL++    
Sbjct: 1670 LTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMH 1729

Query: 315  LLRSEE---ELRQSRAEKDSFLNSLSR-IAQGEGTESFQD-KMATELLDREQKIVKLQQT 369
            L   +E   +LR   +EK + ++++ + +         QD K+  EL      + + Q+T
Sbjct: 1730 LKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQET 1789

Query: 370  IDEQR----ENEKSMEQTMTQYENQLAALRLEVKRLR 402
            ID+ R    E    +       EN  A L+ +++ L+
Sbjct: 1790 IDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELK 1826



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 69/349 (19%), Positives = 154/349 (44%), Gaps = 51/349 (14%)

Query: 128  SYNYQVLNE---ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAK 184
            SY  Q L E   E+ +     E LKE + + +S L+        +  +L+ T  E +   
Sbjct: 869  SYKTQELQEKTREVQERLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLT 928

Query: 185  KKHKDLEQLVNRLAIERS------HATVKV-----KELREQAETAEQ------VAQSRVS 227
            ++  DL+QL   L IER       H TV +     ++LR   E+ +Q        +S++S
Sbjct: 929  QEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKIS 988

Query: 228  EQKARTEFLQAKVAE-----QEKSKAVAXXXXXXXXXXXXXXXXQLQS---FRDRSIRLV 279
            E+ +R   ++    E     Q+K   +                    +    + R I  +
Sbjct: 989  EEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSL 1048

Query: 280  DMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR----QSRAEKDSFLNS 335
              E+    + +     E    +T++ + ++MT    + ++EELR    + + +++     
Sbjct: 1049 IQEKNELQQMLESVIAEKEQLKTDLKENIEMT----IENQEELRLLGDELKKQQEIVAQE 1104

Query: 336  LSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
             +   + EG  S   +    L + E+K+ +  Q + E+++   ++++ M++ + ++    
Sbjct: 1105 KNHAIKKEGELS---RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKIN--- 1158

Query: 396  LEVKRLRNYDCYSKDVSYPELQTEILDL-------HLQVETLSRERTAL 437
             E++ L+N +  +K+++   ++TE L+L       + +V+++++ER  L
Sbjct: 1159 -EIENLKN-ELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVL 1205



 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 81/358 (22%), Positives = 154/358 (43%), Gaps = 32/358 (8%)

Query: 92   KKIERLQ-KENSILQHKVDETSK-KENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            +K E+L  K+ S +Q  V+E  + KE+ +     +QS       L   L +   ++E ++
Sbjct: 1530 EKEEQLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQE---SQEEIQ 1586

Query: 150  EVVASAESMLRVARARIATLER-QLKDTKAEFEIAKKKHKDLE-QLVNRLAI-ERSHATV 206
             ++   E M RV  A    +ER QLK+   E     K+ ++ E Q +   A+ E      
Sbjct: 1587 IMIKEKEEMKRVQEA--LQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMC 1644

Query: 207  KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX 266
            +++ L+EQ ET +   ++  +E    T+ L   + E                        
Sbjct: 1645 EIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQ 1704

Query: 267  QLQSFRDRSIRLVDMERRRCLEYVPCKENEPT---------DRETEI---WKELQMTRGA 314
              ++ R+   R ++ +    + ++  KE++ T         ++  EI    K+L+ +  A
Sbjct: 1705 LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA 1764

Query: 315  L----LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            L    L+ +EELR +         ++ ++ +G  +E   DK++    D E    KLQ+ I
Sbjct: 1765 LKAQDLKIQEELRIAHMHLKEQQETIDKL-RGIVSEK-TDKLSNMQKDLENSNAKLQEKI 1822

Query: 371  DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVE 428
             E + NE  +  T+ +  N+      E+++L+      KD S    + EI +L+L  E
Sbjct: 1823 QELKANEHQL-ITLKKDVNETQKKVSEMEQLKK---QIKDQSLTLSKLEIENLNLAQE 1876



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 59/308 (19%), Positives = 120/308 (38%), Gaps = 13/308 (4%)

Query: 166  IATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSR 225
            +AT +   K T  EF+  K  H D EQ    +  E      ++  L ++A+  +    + 
Sbjct: 805  LATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGAL 864

Query: 226  VSEQKARTEFLQAKVAE-QEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR 284
             +E   +T+ LQ K  E QE+   +                  LQ+  +R   L+  + +
Sbjct: 865  KTELSYKTQELQEKTREVQERLNEM-----EQLKEQLENRDSPLQTV-EREKTLITEKLQ 918

Query: 285  RCLEYVPCKENEPTDRETEIWKELQMTRGALLRS-EEELRQSRAEKDSFLNSLSRIAQGE 343
            + LE V     E  D + ++ + LQ+ R  L     + +  +   ++   N+L  + Q +
Sbjct: 919  QTLEEVKTLTQEKDDLK-QLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQ 977

Query: 344  GT-ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLR 402
             T  + + K++ E+           +T DE ++    +++           L  +VK   
Sbjct: 978  ETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNE 1037

Query: 403  NYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMV 462
              +   K  S   L  E  +L   +E++  E+  L T       M   ++    L    +
Sbjct: 1038 IIEQQRKIFS---LIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDEL 1094

Query: 463  RARKDLAA 470
            + ++++ A
Sbjct: 1095 KKQQEIVA 1102



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 67/338 (19%), Positives = 135/338 (39%), Gaps = 22/338 (6%)

Query: 90   MIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            M KKI  ++   + L++K  E + +  E       Q  + NY+ + + ++KER   + LK
Sbjct: 1153 MQKKINEIENLKNELKNK--ELTLEHMETERLELAQKLNENYEEV-KSITKER---KVLK 1206

Query: 150  EVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVK 209
            E+  S E+     R  I  +E     TK E +IA    K+ ++ ++ L    S  T ++ 
Sbjct: 1207 ELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQII 1266

Query: 210  ELREQAETAEQVAQSRVSEQKARTEFLQ--AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
              ++  E +    Q  +       E L    KV+E +++                    +
Sbjct: 1267 NTQD-LEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTLAR 1325

Query: 268  LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRET------EIWKELQMTRGALLRSEEE 321
            ++  R R        +         ++N  T +E       ++ + ++ T   +  S+ +
Sbjct: 1326 IEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSK 1385

Query: 322  LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME 381
              QS   K+   N  ++I      E F+ K  + LL  E +++ L + + E  +  KS+ 
Sbjct: 1386 QEQSLNMKEKD-NETTKIV--SEMEQFKPK-DSALLRIEIEMLGLSKRLQESHDEMKSVA 1441

Query: 382  QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
            +     +     L+ E  +L+      K++    L+TE
Sbjct: 1442 KEKDDLQRLQEVLQSESDQLKE---NIKEIVAKHLETE 1476



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 65/328 (19%), Positives = 134/328 (40%), Gaps = 32/328 (9%)

Query: 86   DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
            +RD +    E L+ E   L+  + ET  ++ E+     ++    + +   E + K R   
Sbjct: 1687 ERDDLRSVEETLKVERDQLKENLRETITRDLEKQ--EELKIVHMHLKEHQETIDKLRGIV 1744

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
                  +++ +  L  +   +   + ++++   E  IA    K+ ++ +++L    S  T
Sbjct: 1745 SEKTNEISNMQKDLEHSNDALKAQDLKIQE---ELRIAHMHLKEQQETIDKLRGIVSEKT 1801

Query: 206  VKVKELREQAETAEQVAQSRVSEQKARTEFL----------QAKVAEQEKSKAVAXXXXX 255
             K+  +++  E +    Q ++ E KA    L          Q KV+E E+ K        
Sbjct: 1802 DKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSL 1861

Query: 256  XXXXXXXXXXXQLQSFRDR--SIRLVDMER---RRC-----LEYVPCKEN--EPTDRETE 303
                         Q   +    ++ V  ER   RR      LE    KE+  E   R+ E
Sbjct: 1862 TLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLE 1921

Query: 304  IWKELQMTRGALLRSEE---ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE 360
            I +EL+  R      +E   +LR+  +EK   ++ + +    +  +  Q K+  EL  +E
Sbjct: 1922 IQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLD-KSKDELQKKIQ-ELQKKE 1979

Query: 361  QKIVKLQQTIDEQRENEKSMEQTMTQYE 388
             +++++++ ++   +    MEQ   Q+E
Sbjct: 1980 LQLLRVKEDVNMSHKKINEMEQLKKQFE 2007



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 69/354 (19%), Positives = 149/354 (42%), Gaps = 26/354 (7%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L +EL+KE    EAL+E V    S L+   + +  L ++++D   E  I   + KD    
Sbjct: 725  LQKELNKEVEENEALREEVILL-SELKSLPSEVERLRKEIQDKSEELHIITSE-KD---- 778

Query: 194  VNRLAIERSHATVKVKELREQ-AETAEQVAQSRVSEQKARTEFLQAKVAEQ--EKSKAVA 250
              +L  E  H   +V+ L E+  +T + +A ++ + +    EF   K      E+   + 
Sbjct: 779  --KLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMV 836

Query: 251  XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDR--ETEIWKEL 308
                            + Q F D S+  +  E     + +  K  E  +R  E E  KE 
Sbjct: 837  LEENERMNQEIVNLSKEAQKF-DSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQ 895

Query: 309  QMTRGALLRSEEELRQSRAEK-DSFLNSLSRIAQ-GEGTESFQDKMATELLDREQKI-VK 365
               R + L++ E  +    EK    L  +  + Q  +  +  Q+ +  E    +  I   
Sbjct: 896  LENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDT 955

Query: 366  LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD---VSYPELQTEILD 422
            +   ID Q +   ++E ++ Q++  +  L+ ++    + + + ++    +  E Q +++ 
Sbjct: 956  VNMNIDTQEQLRNALE-SLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVG 1014

Query: 423  LHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRI 476
            +  + + L  + T  +TA      ++E+  +   +F+ +++ + +L  +L+  I
Sbjct: 1015 ID-KKQDLEAKNTQTLTADVKDNEIIEQQRK---IFS-LIQEKNELQQMLESVI 1063


>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
          Length = 1976

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 64/340 (18%), Positives = 141/340 (41%), Gaps = 25/340 (7%)

Query: 136  EELSKERAAR-EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            EE+    AA+ + L+E++   ES +     R   L+ + K  +A  +  +++  + E   
Sbjct: 907  EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966

Query: 195  NRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXX 254
             +L +E+  A  K+K++ E+    E      + E+K     ++ ++AE     A      
Sbjct: 967  QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK----LMEDRIAECSSQLAEEEEKA 1022

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCK-ENEPTDRETEIWKELQMTRG 313
                         +    +R  +  + + R+ LE    K + E TD + +I  ELQ    
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKK--EEKTRQELEKAKRKLDGETTDLQDQI-AELQ---- 1075

Query: 314  ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
                  +EL+   A+K+  L     +A+G+     ++     + + + +I +LQ+  + +
Sbjct: 1076 ---AQIDELKLQLAKKEEELQ--GALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130

Query: 374  RENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            + +    E+       +L AL+ E++   +     +++   + + E+ +L   +E  ++ 
Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELR-TKREQEVAELKKALEEETKN 1189

Query: 434  RTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
              A I        M +RH  A +  +  +   K   A L+
Sbjct: 1190 HEAQIQD------MRQRHATALEELSEQLEQAKRFKANLE 1223



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 80/405 (19%), Positives = 179/405 (44%), Gaps = 35/405 (8%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKEN 101
            L+ K + T+ + + E + R    + E  K  +   L+     + + + M  ++   ++E 
Sbjct: 862  LKVKEKQTKVEGELEEMERKHQQLLEE-KNILAEQLQAETELFAEAEEMRARLAAKKQEL 920

Query: 102  SILQHKVDETSKKENEEPPC--HPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML 159
              + H ++   ++E E      +  +    + Q L E+L +E  AR+ L+    +AE+ +
Sbjct: 921  EEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKI 980

Query: 160  RVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE 219
            +     I  LE    D  ++F   KK  +D      R+A E S       +L E+ E A+
Sbjct: 981  KKMEEEILLLE----DQNSKFIKEKKLMED------RIA-ECS------SQLAEEEEKAK 1023

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR--SIR 277
             +A+ R ++Q+     L+ ++ ++EK++                   Q+   + +   ++
Sbjct: 1024 NLAKIR-NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1082

Query: 278  LVDMERRRCLEYVPCKENEPT---DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLN 334
            L   ++   L+    + ++ T   +   ++ +ELQ     L    E  + SR + +    
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1142

Query: 335  SLSRIAQGEGTESFQDKMAT-----EL-LDREQKIVKLQQTIDEQRENEKSMEQTMTQ-Y 387
             LS   +   TE  +D + T     EL   REQ++ +L++ ++E+ +N ++  Q M Q +
Sbjct: 1143 DLSEELEALKTE-LEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRH 1201

Query: 388  ENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
               L  L  ++++ + +   + + +   L+T+  +L  +V+ L +
Sbjct: 1202 ATALEELSEQLEQAKRFKA-NLEKNKQGLETDNKELACEVKVLQQ 1245



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 74/373 (19%), Positives = 150/373 (40%), Gaps = 27/373 (7%)

Query: 88   DTMIKKIERLQKENSIL------QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE 141
            D + K   RLQ+E   L      Q +V    +K+ ++      +  S + +   E    E
Sbjct: 1416 DKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE 1475

Query: 142  RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
              ARE   + ++ A ++     A+    ERQ K  +A+ E       D+ + V+ L   +
Sbjct: 1476 AEAREKETKALSLARALEEALEAK-EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1534

Query: 202  SHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVAEQEKSKAVAXXXXXXXXXX 260
                 +V+E+R Q E  E   Q+   + K R E  +QA  A+ E+               
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQA-TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593

Query: 261  XXXXXXQLQS-----FRDRSIRLVDMERRRC-LEYVPCKENEPTDRETEIWKELQMTRGA 314
                  +L++      + R++ +   ++    L+ +  +         E+ K+L+  +  
Sbjct: 1594 LIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQ 1653

Query: 315  LLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            +   + EL ++RA +D         AQ + +E     +  E+L  ++++   ++      
Sbjct: 1654 MKDYQRELEEARASRDEI------FAQSKESEKKLKSLEAEILQLQEELASSERARRHAE 1707

Query: 375  ENEKSMEQTMTQYENQLAALRLEVKRLR-NYDCYSKDVSYPELQTEILD-----LHLQVE 428
            +    +   +T   +  +AL  E +RL        +++   +   E+L+       LQV+
Sbjct: 1708 QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVD 1767

Query: 429  TLSRERTALITAA 441
            TL+ E  A  +AA
Sbjct: 1768 TLNAELAAERSAA 1780



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 71/338 (21%), Positives = 140/338 (41%), Gaps = 25/338 (7%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            Q  +EEL K    +E   +V    E M R  +  +       +  +AE E+      + E
Sbjct: 855  QAKDEELLK---VKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETEL----FAEAE 907

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
            ++  RLA ++      + +L    E+ E   Q+ Q+   + +A  + L+ ++ E+E ++ 
Sbjct: 908  EMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQ 967

Query: 249  VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                              ++    D++ + +  + ++ +E    + +     E E  K L
Sbjct: 968  KLQLEKVTAEAKIKKMEEEILLLEDQNSKFI--KEKKLMEDRIAECSSQLAEEEEKAKNL 1025

Query: 309  QMTRG--ALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVK 365
               R    ++ S+ E R  + EK    L    R   GE T+  QD++A   L  +   +K
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTD-LQDQIAE--LQAQIDELK 1082

Query: 366  LQ-QTIDEQRENEKSMEQTMTQYENQ----LAALRLEVKRLRNYDCYSKDVSYPELQTEI 420
            LQ    +E+ +   +     T ++N     +  L+ ++  L+  D  S+  S  + + + 
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE-DFESEKASRNKAEKQK 1141

Query: 421  LDLHLQVETLSRE-RTALITAAASRALMLERHERAADL 457
             DL  ++E L  E    L T AA + L  +R +  A+L
Sbjct: 1142 RDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 99/490 (20%), Positives = 206/490 (42%), Gaps = 55/490 (11%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV-----RVLSNLEWKTRNTEFDNDT----ER 57
            A +     H A ++DM  R   A E L E      R  +NLE   +  E DN       +
Sbjct: 1182 ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVK 1241

Query: 58   LHRMVAGIAENLKAKINFSLEI--AKIPWLDR--DTMIKKIERLQKENSILQHKVDETSK 113
            + + V   +E+ + K++  ++   AK+   DR    + +K  +LQ E   +   ++E  K
Sbjct: 1242 VLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEK 1301

Query: 114  KENE-EPPCHPVQSGSYNYQVLNEELSKERA-----------AREALKEVVASAESMLRV 161
            K  +       ++S   + Q L +E ++++             + +L+E     E   + 
Sbjct: 1302 KGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN 1361

Query: 162  ARARIATLERQLKDTKAE----------FEIAKKK-HKDLEQLVNRLAIERSHATVKVKE 210
               ++  L+ QL DTK +           E AKKK  KD E L  RL  E++ A  K+++
Sbjct: 1362 LEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE-EKALAYDKLEK 1420

Query: 211  LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             + + +         +  Q+     L+ K  +++  + +A                + ++
Sbjct: 1421 TKNRLQQELDDLTVDLDHQRQVASNLEKK--QKKFDQLLAEEKSISARYAEERDRAEAEA 1478

Query: 271  FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
             R++  + + +   R LE    +  E  +R+    K+L+     L+ S++++ ++  E +
Sbjct: 1479 -REKETKALSL--ARALEEA-LEAKEEFERQN---KQLRADMEDLMSSKDDVGKNVHELE 1531

Query: 331  SFLNSLSRIAQGEGT--ESFQDKM-ATE----LLDREQKIVKLQQTIDEQRENEKSMEQT 383
                +L +  +   T  E  +D++ ATE     L+   + +K Q   D Q  +E++ E+ 
Sbjct: 1532 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKK 1591

Query: 384  MTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAAS 443
                + Q+  L  E++  R     +   S  +++ ++ DL  Q+E  ++ R  +I     
Sbjct: 1592 RLLIK-QVRELEAELEDERKQRALAV-ASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK 1649

Query: 444  RALMLERHER 453
                ++ ++R
Sbjct: 1650 LQAQMKDYQR 1659



 Score = 35.9 bits (79), Expect = 0.32
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 16/135 (11%)

Query: 132  QVLNEELSKERAAREALKEVVASA-ESMLRVARARIATLERQL----KDTKAEFEIAKKK 186
            Q L  +  + +A  + L+  V S  ++ +    A+I  LE QL    K+  A  ++ ++ 
Sbjct: 1788 QQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRT 1847

Query: 187  HKDLEQLVNRLAIERSHA----------TVKVKELREQAETAEQVA-QSRVSEQKARTEF 235
             K L+++  ++  ER HA            ++K+L+ Q E AE+ A ++  S +K + E 
Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907

Query: 236  LQAKVAEQEKSKAVA 250
              A  A +  S+ V+
Sbjct: 1908 DDATEANEGLSREVS 1922



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 95/447 (21%), Positives = 174/447 (38%), Gaps = 39/447 (8%)

Query: 36   VRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDR-DTMIKKI 94
            ++V+  L+ +    + D ++E+  R     AE  K  ++  LE  K    D  DT   + 
Sbjct: 1110 LKVVRELQAQIAELQEDFESEKASR---NKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166

Query: 95   E-RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
            E R ++E  + + K     + +N E     +Q     +    EELS++    +  K  + 
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQ---IQDMRQRHATALEELSEQLEQAKRFKANLE 1223

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
              +  L      +A   + L+  KAE E    K K L+  V  L     HA V   + R 
Sbjct: 1224 KNKQGLETDNKELACEVKVLQQVKAESE---HKRKKLDAQVQEL-----HAKVSEGD-RL 1274

Query: 214  QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
            + E AE+ ++ +       T      + E+ + K +                 +L     
Sbjct: 1275 RVELAEKASKLQNELDNVST------LLEEAEKKGIKFAKDAASLESQLQDTQELLQEET 1328

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
            R  +L    R R LE       E  + E E  K L+     +L  + +L  ++ + D  L
Sbjct: 1329 RQ-KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEK---QVLALQSQLADTKKKVDDDL 1384

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIV--KLQQTIDEQRENEKSMEQTMTQYENQL 391
             ++  + + +  +  +D  A      E+ +   KL++T  + R  ++  + T+     + 
Sbjct: 1385 GTIESLEEAK-KKLLKDAEALSQRLEEKALAYDKLEKT--KNRLQQELDDLTVDLDHQRQ 1441

Query: 392  AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERH 451
             A  LE K+ +     +++ S      E  D   + E  +RE+    T A S A  LE  
Sbjct: 1442 VASNLEKKQKKFDQLLAEEKSISARYAEERD---RAEAEAREKE---TKALSLARALEEA 1495

Query: 452  ERAADLFARM-VRARKDLAALLDGRID 477
              A + F R   + R D+  L+  + D
Sbjct: 1496 LEAKEEFERQNKQLRADMEDLMSSKDD 1522


>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
            non-muscle protein.
          Length = 1976

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 64/340 (18%), Positives = 141/340 (41%), Gaps = 25/340 (7%)

Query: 136  EELSKERAAR-EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            EE+    AA+ + L+E++   ES +     R   L+ + K  +A  +  +++  + E   
Sbjct: 907  EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966

Query: 195  NRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXX 254
             +L +E+  A  K+K++ E+    E      + E+K     ++ ++AE     A      
Sbjct: 967  QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK----LMEDRIAECSSQLAEEEEKA 1022

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCK-ENEPTDRETEIWKELQMTRG 313
                         +    +R  +  + + R+ LE    K + E TD + +I  ELQ    
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKK--EEKTRQELEKAKRKLDGETTDLQDQI-AELQ---- 1075

Query: 314  ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
                  +EL+   A+K+  L     +A+G+     ++     + + + +I +LQ+  + +
Sbjct: 1076 ---AQIDELKLQLAKKEEELQ--GALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130

Query: 374  RENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            + +    E+       +L AL+ E++   +     +++   + + E+ +L   +E  ++ 
Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELR-TKREQEVAELKKALEEETKN 1189

Query: 434  RTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
              A I        M +RH  A +  +  +   K   A L+
Sbjct: 1190 HEAQIQD------MRQRHATALEELSEQLEQAKRFKANLE 1223



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 80/405 (19%), Positives = 179/405 (44%), Gaps = 35/405 (8%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKEN 101
            L+ K + T+ + + E + R    + E  K  +   L+     + + + M  ++   ++E 
Sbjct: 862  LKVKEKQTKVEGELEEMERKHQQLLEE-KNILAEQLQAETELFAEAEEMRARLAAKKQEL 920

Query: 102  SILQHKVDETSKKENEEPPC--HPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML 159
              + H ++   ++E E      +  +    + Q L E+L +E  AR+ L+    +AE+ +
Sbjct: 921  EEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKI 980

Query: 160  RVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE 219
            +     I  LE    D  ++F   KK  +D      R+A E S       +L E+ E A+
Sbjct: 981  KKMEEEILLLE----DQNSKFIKEKKLMED------RIA-ECS------SQLAEEEEKAK 1023

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR--SIR 277
             +A+ R ++Q+     L+ ++ ++EK++                   Q+   + +   ++
Sbjct: 1024 NLAKIR-NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1082

Query: 278  LVDMERRRCLEYVPCKENEPT---DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLN 334
            L   ++   L+    + ++ T   +   ++ +ELQ     L    E  + SR + +    
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1142

Query: 335  SLSRIAQGEGTESFQDKMAT-----EL-LDREQKIVKLQQTIDEQRENEKSMEQTMTQ-Y 387
             LS   +   TE  +D + T     EL   REQ++ +L++ ++E+ +N ++  Q M Q +
Sbjct: 1143 DLSEELEALKTE-LEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRH 1201

Query: 388  ENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
               L  L  ++++ + +   + + +   L+T+  +L  +V+ L +
Sbjct: 1202 ATALEELSEQLEQAKRFKA-NLEKNKQGLETDNKELACEVKVLQQ 1245



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 74/373 (19%), Positives = 150/373 (40%), Gaps = 27/373 (7%)

Query: 88   DTMIKKIERLQKENSIL------QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE 141
            D + K   RLQ+E   L      Q +V    +K+ ++      +  S + +   E    E
Sbjct: 1416 DKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE 1475

Query: 142  RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
              ARE   + ++ A ++     A+    ERQ K  +A+ E       D+ + V+ L   +
Sbjct: 1476 AEAREKETKALSLARALEEALEAK-EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1534

Query: 202  SHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVAEQEKSKAVAXXXXXXXXXX 260
                 +V+E+R Q E  E   Q+   + K R E  +QA  A+ E+               
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQA-TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593

Query: 261  XXXXXXQLQS-----FRDRSIRLVDMERRRC-LEYVPCKENEPTDRETEIWKELQMTRGA 314
                  +L++      + R++ +   ++    L+ +  +         E+ K+L+  +  
Sbjct: 1594 LIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQ 1653

Query: 315  LLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            +   + EL ++RA +D         AQ + +E     +  E+L  ++++   ++      
Sbjct: 1654 MKDYQRELEEARASRDEI------FAQSKESEKKLKSLEAEILQLQEELASSERARRHAE 1707

Query: 375  ENEKSMEQTMTQYENQLAALRLEVKRLR-NYDCYSKDVSYPELQTEILD-----LHLQVE 428
            +    +   +T   +  +AL  E +RL        +++   +   E+L+       LQV+
Sbjct: 1708 QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVD 1767

Query: 429  TLSRERTALITAA 441
            TL+ E  A  +AA
Sbjct: 1768 TLNAELAAERSAA 1780



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 71/338 (21%), Positives = 140/338 (41%), Gaps = 25/338 (7%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            Q  +EEL K    +E   +V    E M R  +  +       +  +AE E+      + E
Sbjct: 855  QAKDEELLK---VKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETEL----FAEAE 907

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
            ++  RLA ++      + +L    E+ E   Q+ Q+   + +A  + L+ ++ E+E ++ 
Sbjct: 908  EMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQ 967

Query: 249  VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                              ++    D++ + +  + ++ +E    + +     E E  K L
Sbjct: 968  KLQLEKVTAEAKIKKMEEEILLLEDQNSKFI--KEKKLMEDRIAECSSQLAEEEEKAKNL 1025

Query: 309  QMTRG--ALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVK 365
               R    ++ S+ E R  + EK    L    R   GE T+  QD++A   L  +   +K
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTD-LQDQIAE--LQAQIDELK 1082

Query: 366  LQ-QTIDEQRENEKSMEQTMTQYENQ----LAALRLEVKRLRNYDCYSKDVSYPELQTEI 420
            LQ    +E+ +   +     T ++N     +  L+ ++  L+  D  S+  S  + + + 
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE-DFESEKASRNKAEKQK 1141

Query: 421  LDLHLQVETLSRE-RTALITAAASRALMLERHERAADL 457
             DL  ++E L  E    L T AA + L  +R +  A+L
Sbjct: 1142 RDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 99/490 (20%), Positives = 206/490 (42%), Gaps = 55/490 (11%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV-----RVLSNLEWKTRNTEFDNDT----ER 57
            A +     H A ++DM  R   A E L E      R  +NLE   +  E DN       +
Sbjct: 1182 ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVK 1241

Query: 58   LHRMVAGIAENLKAKINFSLEI--AKIPWLDR--DTMIKKIERLQKENSILQHKVDETSK 113
            + + V   +E+ + K++  ++   AK+   DR    + +K  +LQ E   +   ++E  K
Sbjct: 1242 VLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEK 1301

Query: 114  KENE-EPPCHPVQSGSYNYQVLNEELSKERA-----------AREALKEVVASAESMLRV 161
            K  +       ++S   + Q L +E ++++             + +L+E     E   + 
Sbjct: 1302 KGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN 1361

Query: 162  ARARIATLERQLKDTKAE----------FEIAKKK-HKDLEQLVNRLAIERSHATVKVKE 210
               ++  L+ QL DTK +           E AKKK  KD E L  RL  E++ A  K+++
Sbjct: 1362 LEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE-EKALAYDKLEK 1420

Query: 211  LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             + + +         +  Q+     L+ K  +++  + +A                + ++
Sbjct: 1421 TKNRLQQELDDLTVDLDHQRQVASNLEKK--QKKFDQLLAEEKSISARYAEERDRAEAEA 1478

Query: 271  FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
             R++  + + +   R LE    +  E  +R+    K+L+     L+ S++++ ++  E +
Sbjct: 1479 -REKETKALSL--ARALEEA-LEAKEEFERQN---KQLRADMEDLMSSKDDVGKNVHELE 1531

Query: 331  SFLNSLSRIAQGEGT--ESFQDKM-ATE----LLDREQKIVKLQQTIDEQRENEKSMEQT 383
                +L +  +   T  E  +D++ ATE     L+   + +K Q   D Q  +E++ E+ 
Sbjct: 1532 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKK 1591

Query: 384  MTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAAS 443
                + Q+  L  E++  R     +   S  +++ ++ DL  Q+E  ++ R  +I     
Sbjct: 1592 RLLIK-QVRELEAELEDERKQRALAV-ASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK 1649

Query: 444  RALMLERHER 453
                ++ ++R
Sbjct: 1650 LQAQMKDYQR 1659



 Score = 35.9 bits (79), Expect = 0.32
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 16/135 (11%)

Query: 132  QVLNEELSKERAAREALKEVVASA-ESMLRVARARIATLERQL----KDTKAEFEIAKKK 186
            Q L  +  + +A  + L+  V S  ++ +    A+I  LE QL    K+  A  ++ ++ 
Sbjct: 1788 QQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRT 1847

Query: 187  HKDLEQLVNRLAIERSHA----------TVKVKELREQAETAEQVA-QSRVSEQKARTEF 235
             K L+++  ++  ER HA            ++K+L+ Q E AE+ A ++  S +K + E 
Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907

Query: 236  LQAKVAEQEKSKAVA 250
              A  A +  S+ V+
Sbjct: 1908 DDATEANEGLSREVS 1922



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 95/447 (21%), Positives = 174/447 (38%), Gaps = 39/447 (8%)

Query: 36   VRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDR-DTMIKKI 94
            ++V+  L+ +    + D ++E+  R     AE  K  ++  LE  K    D  DT   + 
Sbjct: 1110 LKVVRELQAQIAELQEDFESEKASR---NKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166

Query: 95   E-RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
            E R ++E  + + K     + +N E     +Q     +    EELS++    +  K  + 
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQ---IQDMRQRHATALEELSEQLEQAKRFKANLE 1223

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
              +  L      +A   + L+  KAE E    K K L+  V  L     HA V   + R 
Sbjct: 1224 KNKQGLETDNKELACEVKVLQQVKAESE---HKRKKLDAQVQEL-----HAKVSEGD-RL 1274

Query: 214  QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
            + E AE+ ++ +       T      + E+ + K +                 +L     
Sbjct: 1275 RVELAEKASKLQNELDNVST------LLEEAEKKGIKFAKDAASLESQLQDTQELLQEET 1328

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
            R  +L    R R LE       E  + E E  K L+     +L  + +L  ++ + D  L
Sbjct: 1329 RQ-KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEK---QVLALQSQLADTKKKVDDDL 1384

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIV--KLQQTIDEQRENEKSMEQTMTQYENQL 391
             ++  + + +  +  +D  A      E+ +   KL++T  + R  ++  + T+     + 
Sbjct: 1385 GTIESLEEAK-KKLLKDAEALSQRLEEKALAYDKLEKT--KNRLQQELDDLTVDLDHQRQ 1441

Query: 392  AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERH 451
             A  LE K+ +     +++ S      E  D   + E  +RE+    T A S A  LE  
Sbjct: 1442 VASNLEKKQKKFDQLLAEEKSISARYAEERD---RAEAEAREKE---TKALSLARALEEA 1495

Query: 452  ERAADLFARM-VRARKDLAALLDGRID 477
              A + F R   + R D+  L+  + D
Sbjct: 1496 LEAKEEFERQNKQLRADMEDLMSSKDD 1522


>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
            non-muscle protein.
          Length = 1976

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 64/340 (18%), Positives = 141/340 (41%), Gaps = 25/340 (7%)

Query: 136  EELSKERAAR-EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            EE+    AA+ + L+E++   ES +     R   L+ + K  +A  +  +++  + E   
Sbjct: 907  EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966

Query: 195  NRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXX 254
             +L +E+  A  K+K++ E+    E      + E+K     ++ ++AE     A      
Sbjct: 967  QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK----LMEDRIAECSSQLAEEEEKA 1022

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCK-ENEPTDRETEIWKELQMTRG 313
                         +    +R  +  + + R+ LE    K + E TD + +I  ELQ    
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKK--EEKTRQELEKAKRKLDGETTDLQDQI-AELQ---- 1075

Query: 314  ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
                  +EL+   A+K+  L     +A+G+     ++     + + + +I +LQ+  + +
Sbjct: 1076 ---AQIDELKLQLAKKEEELQ--GALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130

Query: 374  RENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            + +    E+       +L AL+ E++   +     +++   + + E+ +L   +E  ++ 
Sbjct: 1131 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELR-TKREQEVAELKKALEEETKN 1189

Query: 434  RTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
              A I        M +RH  A +  +  +   K   A L+
Sbjct: 1190 HEAQIQD------MRQRHATALEELSEQLEQAKRFKANLE 1223



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 80/405 (19%), Positives = 179/405 (44%), Gaps = 35/405 (8%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKEN 101
            L+ K + T+ + + E + R    + E  K  +   L+     + + + M  ++   ++E 
Sbjct: 862  LKVKEKQTKVEGELEEMERKHQQLLEE-KNILAEQLQAETELFAEAEEMRARLAAKKQEL 920

Query: 102  SILQHKVDETSKKENEEPPC--HPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML 159
              + H ++   ++E E      +  +    + Q L E+L +E  AR+ L+    +AE+ +
Sbjct: 921  EEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKI 980

Query: 160  RVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE 219
            +     I  LE    D  ++F   KK  +D      R+A E S       +L E+ E A+
Sbjct: 981  KKMEEEILLLE----DQNSKFIKEKKLMED------RIA-ECS------SQLAEEEEKAK 1023

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR--SIR 277
             +A+ R ++Q+     L+ ++ ++EK++                   Q+   + +   ++
Sbjct: 1024 NLAKIR-NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1082

Query: 278  LVDMERRRCLEYVPCKENEPT---DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLN 334
            L   ++   L+    + ++ T   +   ++ +ELQ     L    E  + SR + +    
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1142

Query: 335  SLSRIAQGEGTESFQDKMAT-----EL-LDREQKIVKLQQTIDEQRENEKSMEQTMTQ-Y 387
             LS   +   TE  +D + T     EL   REQ++ +L++ ++E+ +N ++  Q M Q +
Sbjct: 1143 DLSEELEALKTE-LEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRH 1201

Query: 388  ENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
               L  L  ++++ + +   + + +   L+T+  +L  +V+ L +
Sbjct: 1202 ATALEELSEQLEQAKRFKA-NLEKNKQGLETDNKELACEVKVLQQ 1245



 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 74/373 (19%), Positives = 150/373 (40%), Gaps = 27/373 (7%)

Query: 88   DTMIKKIERLQKENSIL------QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE 141
            D + K   RLQ+E   L      Q +V    +K+ ++      +  S + +   E    E
Sbjct: 1416 DKLEKTKNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE 1475

Query: 142  RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
              ARE   + ++ A ++     A+    ERQ K  +A+ E       D+ + V+ L   +
Sbjct: 1476 AEAREKETKALSLARALEEALEAK-EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1534

Query: 202  SHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVAEQEKSKAVAXXXXXXXXXX 260
                 +V+E+R Q E  E   Q+   + K R E  +QA  A+ E+               
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQA-TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593

Query: 261  XXXXXXQLQS-----FRDRSIRLVDMERRRC-LEYVPCKENEPTDRETEIWKELQMTRGA 314
                  +L++      + R++ +   ++    L+ +  +         E+ K+L+  +  
Sbjct: 1594 LIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQ 1653

Query: 315  LLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            +   + EL ++RA +D         AQ + +E     +  E+L  ++++   ++      
Sbjct: 1654 MKDYQRELEEARASRDEI------FAQSKESEKKLKSLEAEILQLQEELASSERARRHAE 1707

Query: 375  ENEKSMEQTMTQYENQLAALRLEVKRLR-NYDCYSKDVSYPELQTEILD-----LHLQVE 428
            +    +   +T   +  +AL  E +RL        +++   +   E+L+       LQV+
Sbjct: 1708 QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVD 1767

Query: 429  TLSRERTALITAA 441
            TL+ E  A  +AA
Sbjct: 1768 TLNAELAAERSAA 1780



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 71/338 (21%), Positives = 140/338 (41%), Gaps = 25/338 (7%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            Q  +EEL K    +E   +V    E M R  +  +       +  +AE E+      + E
Sbjct: 855  QAKDEELLK---VKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETEL----FAEAE 907

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
            ++  RLA ++      + +L    E+ E   Q+ Q+   + +A  + L+ ++ E+E ++ 
Sbjct: 908  EMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQ 967

Query: 249  VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                              ++    D++ + +  + ++ +E    + +     E E  K L
Sbjct: 968  KLQLEKVTAEAKIKKMEEEILLLEDQNSKFI--KEKKLMEDRIAECSSQLAEEEEKAKNL 1025

Query: 309  QMTRG--ALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVK 365
               R    ++ S+ E R  + EK    L    R   GE T+  QD++A   L  +   +K
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTD-LQDQIAE--LQAQIDELK 1082

Query: 366  LQ-QTIDEQRENEKSMEQTMTQYENQ----LAALRLEVKRLRNYDCYSKDVSYPELQTEI 420
            LQ    +E+ +   +     T ++N     +  L+ ++  L+  D  S+  S  + + + 
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE-DFESEKASRNKAEKQK 1141

Query: 421  LDLHLQVETLSRE-RTALITAAASRALMLERHERAADL 457
             DL  ++E L  E    L T AA + L  +R +  A+L
Sbjct: 1142 RDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 99/490 (20%), Positives = 206/490 (42%), Gaps = 55/490 (11%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV-----RVLSNLEWKTRNTEFDNDT----ER 57
            A +     H A ++DM  R   A E L E      R  +NLE   +  E DN       +
Sbjct: 1182 ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVK 1241

Query: 58   LHRMVAGIAENLKAKINFSLEI--AKIPWLDR--DTMIKKIERLQKENSILQHKVDETSK 113
            + + V   +E+ + K++  ++   AK+   DR    + +K  +LQ E   +   ++E  K
Sbjct: 1242 VLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEK 1301

Query: 114  KENE-EPPCHPVQSGSYNYQVLNEELSKERA-----------AREALKEVVASAESMLRV 161
            K  +       ++S   + Q L +E ++++             + +L+E     E   + 
Sbjct: 1302 KGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN 1361

Query: 162  ARARIATLERQLKDTKAE----------FEIAKKK-HKDLEQLVNRLAIERSHATVKVKE 210
               ++  L+ QL DTK +           E AKKK  KD E L  RL  E++ A  K+++
Sbjct: 1362 LEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE-EKALAYDKLEK 1420

Query: 211  LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             + + +         +  Q+     L+ K  +++  + +A                + ++
Sbjct: 1421 TKNRLQQEPDDLTVDLDHQRQVASNLEKK--QKKFDQLLAEEKSISARYAEERDRAEAEA 1478

Query: 271  FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
             R++  + + +   R LE    +  E  +R+    K+L+     L+ S++++ ++  E +
Sbjct: 1479 -REKETKALSL--ARALEEA-LEAKEEFERQN---KQLRADMEDLMSSKDDVGKNVHELE 1531

Query: 331  SFLNSLSRIAQGEGT--ESFQDKM-ATE----LLDREQKIVKLQQTIDEQRENEKSMEQT 383
                +L +  +   T  E  +D++ ATE     L+   + +K Q   D Q  +E++ E+ 
Sbjct: 1532 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKK 1591

Query: 384  MTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAAS 443
                + Q+  L  E++  R     +   S  +++ ++ DL  Q+E  ++ R  +I     
Sbjct: 1592 RLLIK-QVRELEAELEDERKQRALAV-ASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK 1649

Query: 444  RALMLERHER 453
                ++ ++R
Sbjct: 1650 LQAQMKDYQR 1659



 Score = 35.9 bits (79), Expect = 0.32
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 16/135 (11%)

Query: 132  QVLNEELSKERAAREALKEVVASA-ESMLRVARARIATLERQL----KDTKAEFEIAKKK 186
            Q L  +  + +A  + L+  V S  ++ +    A+I  LE QL    K+  A  ++ ++ 
Sbjct: 1788 QQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRT 1847

Query: 187  HKDLEQLVNRLAIERSHA----------TVKVKELREQAETAEQVA-QSRVSEQKARTEF 235
             K L+++  ++  ER HA            ++K+L+ Q E AE+ A ++  S +K + E 
Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907

Query: 236  LQAKVAEQEKSKAVA 250
              A  A +  S+ V+
Sbjct: 1908 DDATEANEGLSREVS 1922



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 95/447 (21%), Positives = 174/447 (38%), Gaps = 39/447 (8%)

Query: 36   VRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDR-DTMIKKI 94
            ++V+  L+ +    + D ++E+  R     AE  K  ++  LE  K    D  DT   + 
Sbjct: 1110 LKVVRELQAQIAELQEDFESEKASR---NKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166

Query: 95   E-RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
            E R ++E  + + K     + +N E     +Q     +    EELS++    +  K  + 
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQ---IQDMRQRHATALEELSEQLEQAKRFKANLE 1223

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
              +  L      +A   + L+  KAE E    K K L+  V  L     HA V   + R 
Sbjct: 1224 KNKQGLETDNKELACEVKVLQQVKAESE---HKRKKLDAQVQEL-----HAKVSEGD-RL 1274

Query: 214  QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
            + E AE+ ++ +       T      + E+ + K +                 +L     
Sbjct: 1275 RVELAEKASKLQNELDNVST------LLEEAEKKGIKFAKDAASLESQLQDTQELLQEET 1328

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
            R  +L    R R LE       E  + E E  K L+     +L  + +L  ++ + D  L
Sbjct: 1329 RQ-KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEK---QVLALQSQLADTKKKVDDDL 1384

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIV--KLQQTIDEQRENEKSMEQTMTQYENQL 391
             ++  + + +  +  +D  A      E+ +   KL++T  + R  ++  + T+     + 
Sbjct: 1385 GTIESLEEAK-KKLLKDAEALSQRLEEKALAYDKLEKT--KNRLQQEPDDLTVDLDHQRQ 1441

Query: 392  AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERH 451
             A  LE K+ +     +++ S      E  D   + E  +RE+    T A S A  LE  
Sbjct: 1442 VASNLEKKQKKFDQLLAEEKSISARYAEERD---RAEAEAREKE---TKALSLARALEEA 1495

Query: 452  ERAADLFARM-VRARKDLAALLDGRID 477
              A + F R   + R D+  L+  + D
Sbjct: 1496 LEAKEEFERQNKQLRADMEDLMSSKDD 1522


>AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110kDa
           protein.
          Length = 1007

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 68/332 (20%), Positives = 141/332 (42%), Gaps = 27/332 (8%)

Query: 88  DTMIKKIERLQKENSILQHKVDETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKER 142
           + + K+ E LQ++  I + K+ +T +     +EN +     ++    N + L +EL +  
Sbjct: 465 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN 524

Query: 143 AAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK------KHKD-LEQLVN 195
             + +L   +++ +  L+  R  + +L+ +L + +    +AK+      KH+D L     
Sbjct: 525 RDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQT 584

Query: 196 RLAIERSHATVKVKELREQAETAE---QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
           RL  + S    + ++ +++ ET +   QV Q+ + E K +    +      +K +     
Sbjct: 585 RLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEES 644

Query: 253 XXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE-LQM 310
                         QL+    D+  +L D    + L     +E   T +E E W E L+ 
Sbjct: 645 KLETSKVTLKEQQHQLEKELTDQKSKL-DQVLSKVL---AAEERVRTLQEEERWCESLEK 700

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDREQKIVKLQQ 368
           T     R   E  Q   EK   L +L + A     +    +++  TE    E+++  L++
Sbjct: 701 TLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKE 760

Query: 369 TIDEQREN-EKSM---EQTMTQYENQLAALRL 396
            +  QR   EK++   +Q  +  + ++A + L
Sbjct: 761 ALKIQRSQLEKNLLEQKQENSCIQKEMATIEL 792



 Score = 44.0 bits (99), Expect = 0.001
 Identities = 74/394 (18%), Positives = 158/394 (40%), Gaps = 26/394 (6%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEE---LSKER 142
           D   + KK E+L +E   LQ  ++   + E+            ++ QVL E    L  +R
Sbjct: 214 DFQCLSKKKEKLTEELQKLQKDIEMAERNED------------HHLQVLKESEVLLQAKR 261

Query: 143 AAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERS 202
           A  E LK  V S +  + V   ++   + +L   +     AK   ++  +L      E+ 
Sbjct: 262 AELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKC 321

Query: 203 HATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
           +   +VK L E+    +     ++SE+K +   ++ ++ ++E++  V             
Sbjct: 322 NHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELK 381

Query: 263 XXXX--QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEE 320
                 QL++   + ++L   +R   LE       E       + +  Q  +G +   ++
Sbjct: 382 NILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQ 441

Query: 321 ELRQSRAEKDSFLNSLSRIAQG--EGTESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
            L + + E +  + + SR  Q   E     ++ +  +    E+K+ + ++ +    EN K
Sbjct: 442 LLERDKREIER-MTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSK 500

Query: 379 SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL- 437
             +  + + E  +  L+ E+ +L N D  S       +Q ++ +    V +L  E   + 
Sbjct: 501 MEQSNLEKLELNVRKLQQELDQL-NRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQ 559

Query: 438 --ITAAASRALMLERHERAADLFARMVRARKDLA 469
             +  A    L   +H+    L +   R +KD++
Sbjct: 560 DHLNLAKQDLLHTTKHQDV--LLSEQTRLQKDIS 591



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 2/90 (2%)

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
           +L    ++L Q + +++  L  +++I   + ++        E L  E  + KLQ+ I+  
Sbjct: 182 SLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEE--LQKLQKDIEMA 239

Query: 374 RENEKSMEQTMTQYENQLAALRLEVKRLRN 403
             NE    Q + + E  L A R E+++L++
Sbjct: 240 ERNEDHHLQVLKESEVLLQAKRAELEKLKS 269


>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
            protein.
          Length = 1939

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 64/357 (17%), Positives = 148/357 (41%), Gaps = 18/357 (5%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            R+   +K+ R   E S LQH+    + ++        +     + Q + ++L KE++  E
Sbjct: 1171 REAEFQKMRR-DLEESTLQHEATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKS--E 1227

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
               E+   A +M  V++A+ A  E+  +  + +    K K ++ ++L+N L+ +++    
Sbjct: 1228 LKMEINDLASNMETVSKAK-ANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHT 1286

Query: 207  KVKELREQAETAEQVAQSRVSEQKART---EFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            +  E   Q +  + +       ++A T   E L+ ++ E+ K+K+               
Sbjct: 1287 ESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDL 1346

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEE 321
               Q +  ++    L     +   E    +    TD  + TE  +E +      L+  EE
Sbjct: 1347 LREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406

Query: 322  LRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRENE 377
              ++   K + L    +  Q E  +   D      A   LD++Q+     + + E ++  
Sbjct: 1407 HVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQR--NFDKVLAEWKQKY 1464

Query: 378  KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
            +  +  +   + +  +L  E+ +++N   Y + + + E L+ E  +L  ++  L+ +
Sbjct: 1465 EETQAELEASQKESRSLSTELFKVKN--AYEESLDHLETLKRENKNLQQEISDLTEQ 1519



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 51/295 (17%), Positives = 120/295 (40%), Gaps = 18/295 (6%)

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +K ++ SAE+        +A ++ + + TK E    + K K+LE+ +  L  E++   ++
Sbjct: 840  IKPLLKSAET-----EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ 894

Query: 208  VK----ELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            V+     L +  E  +Q+ ++++ + +A+ + +  +  ++E+  A               
Sbjct: 895  VQAEADALADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 953

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
                +    + ++  V+ E+      V     E    +  I K L   + AL  + ++  
Sbjct: 954  LKKDIDDL-ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK-LTKEKKALQEAHQQTL 1011

Query: 324  QSRAEKDSFLNSLSRI-----AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
                 ++  +N+L++       Q +  E   ++     +D E+   KL+  +   +E+  
Sbjct: 1012 DDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTM 1071

Query: 379  SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
              E    Q   +L     E+  L+      +     +LQ +I +L  ++E L  E
Sbjct: 1072 DTENDKQQLNEKLKKKEFEMSNLQG-KIEDEQALAMQLQKKIKELQARIEELEEE 1125



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 63/348 (18%), Positives = 140/348 (40%), Gaps = 34/348 (9%)

Query: 63   AGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCH 122
            A +  + K   + S E+ K+     +++   +E L++EN  LQ ++ + +++        
Sbjct: 1469 AELEASQKESRSLSTELFKVKNAYEESL-DHLETLKRENKNLQQEISDLTEQ-------- 1519

Query: 123  PVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEI 182
             +  G  +   L +   +    +  L+  +  AE+ L     +I  ++ +L   K+E + 
Sbjct: 1520 -IAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDR 1578

Query: 183  A-KKKHKDLEQLV-NRLAIERSHATVKVKELREQAETA--EQVAQSRVSEQKARTEFLQA 238
               +K ++L+QL  N L +  S  +    E+R + +    ++  +  ++E + +      
Sbjct: 1579 KIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANR 1638

Query: 239  KVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPT 298
            + AE  ++                     ++   D   +L  +ERR  L     +E   +
Sbjct: 1639 QAAEALRN---LRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRAS 1695

Query: 299  DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIA------QGEGTESFQD-- 350
               TE  +  +M    LL + E ++    +  S +N+  ++       QGE  +  Q+  
Sbjct: 1696 LERTE--RGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEAR 1753

Query: 351  -------KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
                   K  T+     +++ K Q T       +K+MEQT+   + +L
Sbjct: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1801



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 38/181 (20%), Positives = 78/181 (43%), Gaps = 11/181 (6%)

Query: 207  KVKELREQAETAEQVAQSRVSEQKARTEF--LQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            K+K L + AET +++A  +   +K + E    +AK  E E+                   
Sbjct: 839  KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               L    +R  +L+  + +  LE    +  E  + E EI  EL   +  L   E+E  +
Sbjct: 899  ADALADAEERCDQLIKTKIQ--LEAKIKEVTERAEDEEEINAELTAKKRKL---EDECSE 953

Query: 325  SRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
             + + D    +L+++  +   TE+    +  E+   ++ I KL +   E++  +++ +QT
Sbjct: 954  LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK---EKKALQEAHQQT 1010

Query: 384  M 384
            +
Sbjct: 1011 L 1011


>AF083322-1|AAC32373.1|  994|Homo sapiens centriole associated
           protein CEP110 protein.
          Length = 994

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 77/421 (18%), Positives = 167/421 (39%), Gaps = 23/421 (5%)

Query: 67  ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
           E L   I+  L+  K    + + + + +++ Q++   +   V+    +   E      + 
Sbjct: 26  EELHHNIDDLLQEKKSLECEVEELHRTVQKRQRQKDFIDGNVESLMTELEIEKSLKHHED 85

Query: 127 GSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKK 186
                + + + L K R+       ++A AES L   + +      +  D K      +  
Sbjct: 86  IVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESD 145

Query: 187 HKDLEQLVNRLAIERSHATVKVKELREQAETAEQ--VAQSRVSEQ-----KARTEFLQAK 239
            ++LE+     A+    A  +++ L+  A+  EQ  + Q  + ++      A+    Q  
Sbjct: 146 AEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCL 205

Query: 240 VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRL----VDMERRRCLEYVPCKEN 295
             ++EK                      LQ  ++  + L     ++E+ +       +E 
Sbjct: 206 SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEM 265

Query: 296 EPTDRETEIWK-ELQMTRGALLRS----EEELRQSRAEKDSFLNSLSRIAQGEGTESFQ- 349
              DR+    K EL + +G+++++    +E LR    E     N +  +       SFQ 
Sbjct: 266 AVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK 325

Query: 350 DKMATELLDREQKIVKLQQTIDEQREN----EKSMEQTMTQYENQLAALRLEVKRLRNYD 405
            ++  ++ +R+ ++  ++Q I+++ EN     + M +  T+ +N L  L+LE   L+   
Sbjct: 326 GELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELQNILDMLQLENHELQGLK 385

Query: 406 C-YSKDVSYPE-LQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVR 463
             + + VS  E  Q  +L+  L++E L +           +  +LER +R  +      R
Sbjct: 386 LQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESR 445

Query: 464 A 464
           A
Sbjct: 446 A 446



 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 68/332 (20%), Positives = 141/332 (42%), Gaps = 27/332 (8%)

Query: 88  DTMIKKIERLQKENSILQHKVDETSK-----KENEEPPCHPVQSGSYNYQVLNEELSKER 142
           + + K+ E LQ++  I + K+ +T +     +EN +     ++    N + L +EL +  
Sbjct: 452 ECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLDLNVRKLQQELDQLN 511

Query: 143 AAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK------KHKD-LEQLVN 195
             + +L   +++ +  L+  R  + +L+ +L + +    +AK+      KH+D L     
Sbjct: 512 RDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQT 571

Query: 196 RLAIERSHATVKVKELREQAETAE---QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
           RL  + S    + ++ +++ ET +   QV Q+ + E K +    +      +K +     
Sbjct: 572 RLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEES 631

Query: 253 XXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE-LQM 310
                         QL+    D+  +L D    + L     +E   T +E E W E L+ 
Sbjct: 632 KLETSKVTLKEQQHQLEKELTDQKSKL-DQVLSKVL---AAEERVRTLQEEERWCESLEK 687

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTE--SFQDKMATELLDREQKIVKLQQ 368
           T     R   E  Q   EK   L +L + A     +    +++  TE    E+++  L++
Sbjct: 688 TLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKE 747

Query: 369 TIDEQREN-EKSM---EQTMTQYENQLAALRL 396
            +  QR   EK++   +Q  +  + ++A + L
Sbjct: 748 ALKIQRSQLEKNLLEQKQENSCIQKEMATIEL 779


>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
            protein.
          Length = 2018

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 64/340 (18%), Positives = 141/340 (41%), Gaps = 25/340 (7%)

Query: 136  EELSKERAAR-EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
            EE+    AA+ + L+E++   ES +     R   L+ + K  +A  +  +++  + E   
Sbjct: 949  EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 1008

Query: 195  NRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXX 254
             +L +E+  A  K+K++ E+    E      + E+K     ++ ++AE     A      
Sbjct: 1009 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK----LMEDRIAECSSQLAEEEEKA 1064

Query: 255  XXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCK-ENEPTDRETEIWKELQMTRG 313
                         +    +R  +  + + R+ LE    K + E TD + +I  ELQ    
Sbjct: 1065 KNLAKIRNKQEVMISDLEERLKK--EEKTRQELEKAKRKLDGETTDLQDQI-AELQ---- 1117

Query: 314  ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
                  +EL+   A+K+  L     +A+G+     ++     + + + +I +LQ+  + +
Sbjct: 1118 ---AQIDELKLQLAKKEEELQ--GALARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1172

Query: 374  RENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            + +    E+       +L AL+ E++   +     +++   + + E+ +L   +E  ++ 
Sbjct: 1173 KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELR-TKREQEVAELKKALEEETKN 1231

Query: 434  RTALITAAASRALMLERHERAADLFARMVRARKDLAALLD 473
              A I        M +RH  A +  +  +   K   A L+
Sbjct: 1232 HEAQIQD------MRQRHATALEELSEQLEQAKRFKANLE 1265



 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 80/405 (19%), Positives = 179/405 (44%), Gaps = 35/405 (8%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKEN 101
            L+ K + T+ + + E + R    + E  K  +   L+     + + + M  ++   ++E 
Sbjct: 904  LKVKEKQTKVEGELEEMERKHQQLLEE-KNILAEQLQAETELFAEAEEMRARLAAKKQEL 962

Query: 102  SILQHKVDETSKKENEEPPC--HPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML 159
              + H ++   ++E E      +  +    + Q L E+L +E  AR+ L+    +AE+ +
Sbjct: 963  EEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKI 1022

Query: 160  RVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE 219
            +     I  LE    D  ++F   KK  +D      R+A E S       +L E+ E A+
Sbjct: 1023 KKMEEEILLLE----DQNSKFIKEKKLMED------RIA-ECS------SQLAEEEEKAK 1065

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR--SIR 277
             +A+ R ++Q+     L+ ++ ++EK++                   Q+   + +   ++
Sbjct: 1066 NLAKIR-NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1124

Query: 278  LVDMERRRCLEYVPCKENEPT---DRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLN 334
            L   ++   L+    + ++ T   +   ++ +ELQ     L    E  + SR + +    
Sbjct: 1125 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1184

Query: 335  SLSRIAQGEGTESFQDKMAT-----EL-LDREQKIVKLQQTIDEQRENEKSMEQTMTQ-Y 387
             LS   +   TE  +D + T     EL   REQ++ +L++ ++E+ +N ++  Q M Q +
Sbjct: 1185 DLSEELEALKTE-LEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRH 1243

Query: 388  ENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
               L  L  ++++ + +   + + +   L+T+  +L  +V+ L +
Sbjct: 1244 ATALEELSEQLEQAKRFKA-NLEKNKQGLETDNKELACEVKVLQQ 1287



 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 74/373 (19%), Positives = 150/373 (40%), Gaps = 27/373 (7%)

Query: 88   DTMIKKIERLQKENSIL------QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE 141
            D + K   RLQ+E   L      Q +V    +K+ ++      +  S + +   E    E
Sbjct: 1458 DKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE 1517

Query: 142  RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
              ARE   + ++ A ++     A+    ERQ K  +A+ E       D+ + V+ L   +
Sbjct: 1518 AEAREKETKALSLARALEEALEAK-EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSK 1576

Query: 202  SHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVAEQEKSKAVAXXXXXXXXXX 260
                 +V+E+R Q E  E   Q+   + K R E  +QA  A+ E+               
Sbjct: 1577 RALEQQVEEMRTQLEELEDELQA-TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1635

Query: 261  XXXXXXQLQS-----FRDRSIRLVDMERRRC-LEYVPCKENEPTDRETEIWKELQMTRGA 314
                  +L++      + R++ +   ++    L+ +  +         E+ K+L+  +  
Sbjct: 1636 LIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQ 1695

Query: 315  LLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            +   + EL ++RA +D         AQ + +E     +  E+L  ++++   ++      
Sbjct: 1696 MKDYQRELEEARASRDEI------FAQSKESEKKLKSLEAEILQLQEELASSERARRHAE 1749

Query: 375  ENEKSMEQTMTQYENQLAALRLEVKRLR-NYDCYSKDVSYPELQTEILD-----LHLQVE 428
            +    +   +T   +  +AL  E +RL        +++   +   E+L+       LQV+
Sbjct: 1750 QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVD 1809

Query: 429  TLSRERTALITAA 441
            TL+ E  A  +AA
Sbjct: 1810 TLNAELAAERSAA 1822



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 71/338 (21%), Positives = 140/338 (41%), Gaps = 25/338 (7%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            Q  +EEL K    +E   +V    E M R  +  +       +  +AE E+      + E
Sbjct: 897  QAKDEELLK---VKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETEL----FAEAE 949

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
            ++  RLA ++      + +L    E+ E   Q+ Q+   + +A  + L+ ++ E+E ++ 
Sbjct: 950  EMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQ 1009

Query: 249  VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                              ++    D++ + +  + ++ +E    + +     E E  K L
Sbjct: 1010 KLQLEKVTAEAKIKKMEEEILLLEDQNSKFI--KEKKLMEDRIAECSSQLAEEEEKAKNL 1067

Query: 309  QMTRG--ALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVK 365
               R    ++ S+ E R  + EK    L    R   GE T+  QD++A   L  +   +K
Sbjct: 1068 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTD-LQDQIAE--LQAQIDELK 1124

Query: 366  LQ-QTIDEQRENEKSMEQTMTQYENQ----LAALRLEVKRLRNYDCYSKDVSYPELQTEI 420
            LQ    +E+ +   +     T ++N     +  L+ ++  L+  D  S+  S  + + + 
Sbjct: 1125 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE-DFESEKASRNKAEKQK 1183

Query: 421  LDLHLQVETLSRE-RTALITAAASRALMLERHERAADL 457
             DL  ++E L  E    L T AA + L  +R +  A+L
Sbjct: 1184 RDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1221



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 99/490 (20%), Positives = 206/490 (42%), Gaps = 55/490 (11%)

Query: 7    AQQNSLLEHYAILRDMESRAGVAAETLGEV-----RVLSNLEWKTRNTEFDNDT----ER 57
            A +     H A ++DM  R   A E L E      R  +NLE   +  E DN       +
Sbjct: 1224 ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVK 1283

Query: 58   LHRMVAGIAENLKAKINFSLEI--AKIPWLDR--DTMIKKIERLQKENSILQHKVDETSK 113
            + + V   +E+ + K++  ++   AK+   DR    + +K  +LQ E   +   ++E  K
Sbjct: 1284 VLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEK 1343

Query: 114  KENE-EPPCHPVQSGSYNYQVLNEELSKERA-----------AREALKEVVASAESMLRV 161
            K  +       ++S   + Q L +E ++++             + +L+E     E   + 
Sbjct: 1344 KGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN 1403

Query: 162  ARARIATLERQLKDTKAE----------FEIAKKK-HKDLEQLVNRLAIERSHATVKVKE 210
               ++  L+ QL DTK +           E AKKK  KD E L  RL  E++ A  K+++
Sbjct: 1404 LEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE-EKALAYDKLEK 1462

Query: 211  LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             + + +         +  Q+     L+ K  +++  + +A                + ++
Sbjct: 1463 TKNRLQQELDDLTVDLDHQRQVASNLEKK--QKKFDQLLAEEKSISARYAEERDRAEAEA 1520

Query: 271  FRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
             R++  + + +   R LE    +  E  +R+    K+L+     L+ S++++ ++  E +
Sbjct: 1521 -REKETKALSL--ARALEEA-LEAKEEFERQN---KQLRADMEDLMSSKDDVGKNVHELE 1573

Query: 331  SFLNSLSRIAQGEGT--ESFQDKM-ATE----LLDREQKIVKLQQTIDEQRENEKSMEQT 383
                +L +  +   T  E  +D++ ATE     L+   + +K Q   D Q  +E++ E+ 
Sbjct: 1574 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKK 1633

Query: 384  MTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAAS 443
                + Q+  L  E++  R     +   S  +++ ++ DL  Q+E  ++ R  +I     
Sbjct: 1634 RLLIK-QVRELEAELEDERKQRALAV-ASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK 1691

Query: 444  RALMLERHER 453
                ++ ++R
Sbjct: 1692 LQAQMKDYQR 1701



 Score = 35.9 bits (79), Expect = 0.32
 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 16/135 (11%)

Query: 132  QVLNEELSKERAAREALKEVVASA-ESMLRVARARIATLERQL----KDTKAEFEIAKKK 186
            Q L  +  + +A  + L+  V S  ++ +    A+I  LE QL    K+  A  ++ ++ 
Sbjct: 1830 QQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRT 1889

Query: 187  HKDLEQLVNRLAIERSHA----------TVKVKELREQAETAEQVA-QSRVSEQKARTEF 235
             K L+++  ++  ER HA            ++K+L+ Q E AE+ A ++  S +K + E 
Sbjct: 1890 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1949

Query: 236  LQAKVAEQEKSKAVA 250
              A  A +  S+ V+
Sbjct: 1950 DDATEANEGLSREVS 1964



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 95/447 (21%), Positives = 174/447 (38%), Gaps = 39/447 (8%)

Query: 36   VRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDR-DTMIKKI 94
            ++V+  L+ +    + D ++E+  R     AE  K  ++  LE  K    D  DT   + 
Sbjct: 1152 LKVVRELQAQIAELQEDFESEKASR---NKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1208

Query: 95   E-RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
            E R ++E  + + K     + +N E     +Q     +    EELS++    +  K  + 
Sbjct: 1209 ELRTKREQEVAELKKALEEETKNHEAQ---IQDMRQRHATALEELSEQLEQAKRFKANLE 1265

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
              +  L      +A   + L+  KAE E    K K L+  V  L     HA V   + R 
Sbjct: 1266 KNKQGLETDNKELACEVKVLQQVKAESE---HKRKKLDAQVQEL-----HAKVSEGD-RL 1316

Query: 214  QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
            + E AE+ ++ +       T      + E+ + K +                 +L     
Sbjct: 1317 RVELAEKASKLQNELDNVST------LLEEAEKKGIKFAKDAASLESQLQDTQELLQEET 1370

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFL 333
            R  +L    R R LE       E  + E E  K L+     +L  + +L  ++ + D  L
Sbjct: 1371 RQ-KLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEK---QVLALQSQLADTKKKVDDDL 1426

Query: 334  NSLSRIAQGEGTESFQDKMATELLDREQKIV--KLQQTIDEQRENEKSMEQTMTQYENQL 391
             ++  + + +  +  +D  A      E+ +   KL++T  + R  ++  + T+     + 
Sbjct: 1427 GTIESLEEAK-KKLLKDAEALSQRLEEKALAYDKLEKT--KNRLQQELDDLTVDLDHQRQ 1483

Query: 392  AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERH 451
             A  LE K+ +     +++ S      E  D   + E  +RE+    T A S A  LE  
Sbjct: 1484 VASNLEKKQKKFDQLLAEEKSISARYAEERD---RAEAEAREKE---TKALSLARALEEA 1537

Query: 452  ERAADLFARM-VRARKDLAALLDGRID 477
              A + F R   + R D+  L+  + D
Sbjct: 1538 LEAKEEFERQNKQLRADMEDLMSSKDD 1564


>U93121-1|AAB88727.1|  753|Homo sapiens M-phase phosphoprotein-1
           protein.
          Length = 753

 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 70/352 (19%), Positives = 150/352 (42%), Gaps = 38/352 (10%)

Query: 85  LDRDTMIKKIERLQKE------NSILQHK---VDETSKKENEEPPCHPVQSGSYNYQVLN 135
           L+++++I K+ER  KE      +S+   K   V E   KE      + +Q   +  Q+  
Sbjct: 121 LEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKE 180

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           EE    R   E LKE ++++ +  +  +A +   E    D K +   AKK+ K +++ V+
Sbjct: 181 EEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVS 240

Query: 196 RLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSKAV--- 249
            +  E     +K+ EL ++     Q   + Q  + + K +    + + A Q+  +A    
Sbjct: 241 VMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDL 300

Query: 250 -AXXXXXXXXXXXXXXXXQLQSFRDRSI--RLVDMER---------RRCLEYVPCKENEP 297
                             Q Q  +D+ +  +L ++ER          +C + +  K N+ 
Sbjct: 301 NVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCND-LETKNNQR 359

Query: 298 TDRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA 353
           +++E    T++  +L   +  L  SE++    R  K      +  I Q +  E+ ++K  
Sbjct: 360 SNKEHENNTDVLGKLTNLQDELQESEQKYNADR--KKWLEEKMMLITQAKEAENIRNKEM 417

Query: 354 TELLDREQKIVKLQQTID----EQRENEKSMEQTMTQYENQLAALRLEVKRL 401
            +  +  ++  K Q  ++    +  E +  +++   + +  +AAL +++K L
Sbjct: 418 KKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKAL 469



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 54/307 (17%), Positives = 123/307 (40%), Gaps = 9/307 (2%)

Query: 86  DRDTMIKKI-ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           +++T+I+++ E LQ++N  L  ++    + +        +  G   Y+   +EL      
Sbjct: 49  EKETLIQQLKEELQEKNVTLDVQIQHVVEGKRA---LSELTQGVTCYKAKIKELETILET 105

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
           ++  +   A  E  +    + I  LER LK+ +   + + K  KDL     +L  E +  
Sbjct: 106 QKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQL 165

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
           T  +++++   +  E+  ++   E +   E L A  A  +  KA                
Sbjct: 166 TNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKL 225

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               +  +     +  M     L  +  K NE   ++ +  +EL M +  + + +E+L  
Sbjct: 226 TDAKKQIKQVQKEVSVMRDEDKL--LRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNN 283

Query: 325 SRAEKDSFLNSLSRIAQGEGT-ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
            + E+   +    R  +     E   + M   L ++EQ  V+  Q ++ + E  + +   
Sbjct: 284 QKVEE--AIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATE 341

Query: 384 MTQYENQ 390
           + +++ +
Sbjct: 342 LEKWKEK 348


>BC112391-1|AAI12392.1|  957|Homo sapiens ELKS/RAB6-interacting/CAST
           family member 2 protein.
          Length = 957

 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 94/493 (19%), Positives = 202/493 (40%), Gaps = 57/493 (11%)

Query: 2   RKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTE-FDNDTERLHR 60
           R   +A+  S + H  ++ D + +  +      E+   S L+ +   T+      E    
Sbjct: 328 RTRRMAEAESQVSHLEVILDQKEKENIHLRE--ELHRRSQLQPEPAKTKALQTVIEMKDT 385

Query: 61  MVAGIAENLKAKINFSLEIAKIPWL----DRDTMIKKIERLQKENSILQHKVD----ETS 112
            +A +  N++  +   +++ K   +    DR+  IK+IE  +  +  ++ K+D    E S
Sbjct: 386 KIASLERNIR-DLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELS 444

Query: 113 KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQ 172
           KKE+E      + +     + L+ + S  +   E LKE + + E    + +  +  L  +
Sbjct: 445 KKESE------LLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLR 498

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
           L++ ++      KK K L+ L      E+     +++++++  E  E+    +++  + +
Sbjct: 499 LEEKES---FLNKKTKQLQDLTE----EKGTLAGEIRDMKDMLEVKER----KINVLQKK 547

Query: 233 TEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPC 292
            E LQ ++ +++K                      L +  +        E+ R +E +  
Sbjct: 548 IENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAL-----SEKERIIERLK- 601

Query: 293 KENEPTDRE-TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK 351
           ++ E  DRE  E  +  +     L      L+    EK+S L  L   A           
Sbjct: 602 EQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHA---------SS 652

Query: 352 MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRL------EVKRLRNYD 405
           +A+  L R+ K+  L+  I++++E    +E  + +  N     R+      ++K+L    
Sbjct: 653 LASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEA 712

Query: 406 CYSKDVSYPELQTEI---LDLHLQVETLSRERTALITAAASRAL--MLERHERAADLFAR 460
            Y +D    + Q E+   L++  +VE    ++   I    S  L  M +++++ A+L   
Sbjct: 713 SYYRD-ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHN 771

Query: 461 MVRARKDLAALLD 473
               +K  A LL+
Sbjct: 772 QQLEKKKNAQLLE 784



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 53/235 (22%), Positives = 112/235 (47%), Gaps = 30/235 (12%)

Query: 22  MESRAGVAAETLGEVRVLSNLEWKTR-NTEFDNDTERLHRMVAGIAENL---KAKINFSL 77
           +E +    ++   +++   N+E  +R N EF +  ++L +  +   +     +A+++  L
Sbjct: 671 IEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLL 730

Query: 78  EIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEE 137
           EI K    +++   KKI  L  E+  L+H  D+  K  N +   H            N++
Sbjct: 731 EILKEVENEKNDKDKKIAEL--ESLTLRHMKDQNKKVANLK---H------------NQQ 773

Query: 138 LSKERAAREALKEVVASAESMLRVAR-ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
           L K++ A + L+EV    +SM   ++  +I  L   L+ T+ E +  K +    +Q    
Sbjct: 774 LEKKKNA-QLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQ---S 829

Query: 197 LAIERSH-ATVKV---KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
           LA + +H A +++   K+L E  E  ++   + +SE+ A    L+   ++++K++
Sbjct: 830 LAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQ 884


>BC111550-1|AAI11551.1|  957|Homo sapiens ERC2 protein protein.
          Length = 957

 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 94/493 (19%), Positives = 202/493 (40%), Gaps = 57/493 (11%)

Query: 2   RKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTE-FDNDTERLHR 60
           R   +A+  S + H  ++ D + +  +      E+   S L+ +   T+      E    
Sbjct: 328 RTRRMAEAESQVSHLEVILDQKEKENIHLRE--ELHRRSQLQPEPAKTKALQTVIEMKDT 385

Query: 61  MVAGIAENLKAKINFSLEIAKIPWL----DRDTMIKKIERLQKENSILQHKVD----ETS 112
            +A +  N++  +   +++ K   +    DR+  IK+IE  +  +  ++ K+D    E S
Sbjct: 386 KIASLERNIR-DLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELS 444

Query: 113 KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQ 172
           KKE+E      + +     + L+ + S  +   E LKE + + E    + +  +  L  +
Sbjct: 445 KKESE------LLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLR 498

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
           L++ ++      KK K L+ L      E+     +++++++  E  E+    +++  + +
Sbjct: 499 LEEKES---FLNKKTKQLQDLTE----EKGTLAGEIRDMKDMLEVKER----KINVLQKK 547

Query: 233 TEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPC 292
            E LQ ++ +++K                      L +  +        E+ R +E +  
Sbjct: 548 IENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAL-----SEKERIIERLK- 601

Query: 293 KENEPTDRE-TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK 351
           ++ E  DRE  E  +  +     L      L+    EK+S L  L   A           
Sbjct: 602 EQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHA---------SS 652

Query: 352 MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRL------EVKRLRNYD 405
           +A+  L R+ K+  L+  I++++E    +E  + +  N     R+      ++K+L    
Sbjct: 653 LASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEA 712

Query: 406 CYSKDVSYPELQTEI---LDLHLQVETLSRERTALITAAASRAL--MLERHERAADLFAR 460
            Y +D    + Q E+   L++  +VE    ++   I    S  L  M +++++ A+L   
Sbjct: 713 SYYRD-ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHN 771

Query: 461 MVRARKDLAALLD 473
               +K  A LL+
Sbjct: 772 QQLEKKKNAQLLE 784



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 53/235 (22%), Positives = 112/235 (47%), Gaps = 30/235 (12%)

Query: 22  MESRAGVAAETLGEVRVLSNLEWKTR-NTEFDNDTERLHRMVAGIAENL---KAKINFSL 77
           +E +    ++   +++   N+E  +R N EF +  ++L +  +   +     +A+++  L
Sbjct: 671 IEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLL 730

Query: 78  EIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEE 137
           EI K    +++   KKI  L  E+  L+H  D+  K  N +   H            N++
Sbjct: 731 EILKEVENEKNDKDKKIAEL--ESLTLRHMKDQNKKVANLK---H------------NQQ 773

Query: 138 LSKERAAREALKEVVASAESMLRVAR-ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
           L K++ A + L+EV    +SM   ++  +I  L   L+ T+ E +  K +    +Q    
Sbjct: 774 LEKKKNA-QLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQ---S 829

Query: 197 LAIERSH-ATVKV---KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
           LA + +H A +++   K+L E  E  ++   + +SE+ A    L+   ++++K++
Sbjct: 830 LAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQ 884


>AY739715-1|AAW65984.1|  617|Homo sapiens M-phase phosphoprotein 1
           protein.
          Length = 617

 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 70/352 (19%), Positives = 150/352 (42%), Gaps = 38/352 (10%)

Query: 85  LDRDTMIKKIERLQKE------NSILQHK---VDETSKKENEEPPCHPVQSGSYNYQVLN 135
           L+++++I K+ER  KE      +S+   K   V E   KE      + +Q   +  Q+  
Sbjct: 83  LEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKE 142

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           EE    R   E LKE ++++ +  +  +A +   E    D K +   AKK+ K +++ V+
Sbjct: 143 EEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVS 202

Query: 196 RLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSKAV--- 249
            +  E     +K+ EL ++     Q   + Q  + + K +    + + A Q+  +A    
Sbjct: 203 VMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDL 262

Query: 250 -AXXXXXXXXXXXXXXXXQLQSFRDRSI--RLVDMER---------RRCLEYVPCKENEP 297
                             Q Q  +D+ +  +L ++ER          +C + +  K N+ 
Sbjct: 263 NVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCND-LETKNNQR 321

Query: 298 TDRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA 353
           +++E    T++  +L   +  L  SE++    R  K      +  I Q +  E+ ++K  
Sbjct: 322 SNKEHENNTDVLGKLTNLQDELQESEQKYNADR--KKWLEEKMMLITQAKEAENIRNKEM 379

Query: 354 TELLDREQKIVKLQQTID----EQRENEKSMEQTMTQYENQLAALRLEVKRL 401
            +  +  ++  K Q  ++    +  E +  +++   + +  +AAL +++K L
Sbjct: 380 KKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKAL 431



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 54/307 (17%), Positives = 123/307 (40%), Gaps = 9/307 (2%)

Query: 86  DRDTMIKKI-ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           +++T+I+++ E LQ++N  L  ++    + +        +  G   Y+   +EL      
Sbjct: 11  EKETLIQQLKEELQEKNVTLDVQIQHVVEGKRA---LSELTQGVTCYKAKIKELETILET 67

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
           ++  +   A  E  +    + I  LER LK+ +   + + K  KDL     +L  E +  
Sbjct: 68  QKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQL 127

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
           T  +++++   +  E+  ++   E +   E L A  A  +  KA                
Sbjct: 128 TNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKL 187

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               +  +     +  M     L  +  K NE   ++ +  +EL M +  + + +E+L  
Sbjct: 188 TDAKKQIKQVQKEVSVMRDEDKL--LRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNN 245

Query: 325 SRAEKDSFLNSLSRIAQGEGT-ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
            + E+   +    R  +     E   + M   L ++EQ  V+  Q ++ + E  + +   
Sbjct: 246 QKVEE--AIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATE 303

Query: 384 MTQYENQ 390
           + +++ +
Sbjct: 304 LEKWKEK 310


>AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein 1
           protein.
          Length = 1116

 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 70/352 (19%), Positives = 150/352 (42%), Gaps = 38/352 (10%)

Query: 85  LDRDTMIKKIERLQKE------NSILQHK---VDETSKKENEEPPCHPVQSGSYNYQVLN 135
           L+++++I K+ER  KE      +S+   K   V E   KE      + +Q   +  Q+  
Sbjct: 484 LEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKE 543

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           EE    R   E LKE ++++ +  +  +A +   E    D K +   AKK+ K +++ V+
Sbjct: 544 EEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVS 603

Query: 196 RLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSKAV--- 249
            +  E     +K+ EL ++     Q   + Q  + + K +    + + A Q+  +A    
Sbjct: 604 VMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDL 663

Query: 250 -AXXXXXXXXXXXXXXXXQLQSFRDRSI--RLVDMER---------RRCLEYVPCKENEP 297
                             Q Q  +D+ +  +L ++ER          +C + +  K N+ 
Sbjct: 664 NVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCND-LETKNNQR 722

Query: 298 TDRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA 353
           +++E    T++  +L   +  L  SE++    R  K      +  I Q +  E+ ++K  
Sbjct: 723 SNKEHENNTDVLGKLTNLQDELQESEQKYNADR--KKWLEEKMMLITQAKEAENIRNKEM 780

Query: 354 TELLDREQKIVKLQQTID----EQRENEKSMEQTMTQYENQLAALRLEVKRL 401
            +  +  ++  K Q  ++    +  E +  +++   + +  +AAL +++K L
Sbjct: 781 KKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKAL 832



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 54/307 (17%), Positives = 123/307 (40%), Gaps = 9/307 (2%)

Query: 86  DRDTMIKKI-ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           +++T+I+++ E LQ++N  L  ++    + +        +  G   Y+   +EL      
Sbjct: 412 EKETLIQQLKEELQEKNVTLDVQIQHVVEGKRA---LSELTQGVTCYKAKIKELETILET 468

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
           ++  +   A  E  +    + I  LER LK+ +   + + K  KDL     +L  E +  
Sbjct: 469 QKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQL 528

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
           T  +++++   +  E+  ++   E +   E L A  A  +  KA                
Sbjct: 529 TNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKL 588

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               +  +     +  M     L  +  K NE   ++ +  +EL M +  + + +E+L  
Sbjct: 589 TDAKKQIKQVQKEVSVMRDEDKL--LRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNN 646

Query: 325 SRAEKDSFLNSLSRIAQGEGT-ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
            + E+   +    R  +     E   + M   L ++EQ  V+  Q ++ + E  + +   
Sbjct: 647 QKVEE--AIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATE 704

Query: 384 MTQYENQ 390
           + +++ +
Sbjct: 705 LEKWKEK 711



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 303 EIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
           +I  EL  T+G L++++EEL++   E DS +  L    +   T++ + K    ++D+++ 
Sbjct: 15  QIKAELAKTKGELIKTKEELKKRENESDSLIQELETSIKKIITQNQRIKELINIIDQKED 74

Query: 363 IVKLQQTIDEQREN 376
            +   Q +    EN
Sbjct: 75  TINEFQNLKSLMEN 88


>AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related
            protein protein.
          Length = 1820

 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 70/352 (19%), Positives = 150/352 (42%), Gaps = 38/352 (10%)

Query: 85   LDRDTMIKKIERLQKE------NSILQHK---VDETSKKENEEPPCHPVQSGSYNYQVLN 135
            L+++++I K+ER  KE      +S+   K   V E   KE      + +Q   +  Q+  
Sbjct: 1188 LEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKE 1247

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EE    R   E LKE ++++ +  +  +A +   E    D K +   AKK+ K +++ V+
Sbjct: 1248 EEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVS 1307

Query: 196  RLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSKAV--- 249
             +  E     +K+ EL ++     Q   + Q  + + K +    + + A Q+  +A    
Sbjct: 1308 VMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDL 1367

Query: 250  -AXXXXXXXXXXXXXXXXQLQSFRDRSI--RLVDMER---------RRCLEYVPCKENEP 297
                              Q Q  +D+ +  +L ++ER          +C + +  K N+ 
Sbjct: 1368 NVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCND-LETKNNQR 1426

Query: 298  TDRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMA 353
            +++E    T++  +L   +  L  SE++    R  K      +  I Q +  E+ ++K  
Sbjct: 1427 SNKEHENNTDVLGKLTNLQDELQESEQKYNADR--KKWLEEKMMLITQAKEAENIRNKEM 1484

Query: 354  TELLDREQKIVKLQQTID----EQRENEKSMEQTMTQYENQLAALRLEVKRL 401
             +  +  ++  K Q  ++    +  E +  +++   + +  +AAL +++K L
Sbjct: 1485 KKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKAL 1536



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 54/307 (17%), Positives = 123/307 (40%), Gaps = 9/307 (2%)

Query: 86   DRDTMIKKI-ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
            +++T+I+++ E LQ++N  L  ++    + +        +  G   Y+   +EL      
Sbjct: 1116 EKETLIQQLKEELQEKNVTLDVQIQHVVEGKRA---LSELTQGVTCYKAKIKELETILET 1172

Query: 145  REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            ++  +   A  E  +    + I  LER LK+ +   + + K  KDL     +L  E +  
Sbjct: 1173 QKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQL 1232

Query: 205  TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            T  +++++   +  E+  ++   E +   E L A  A  +  KA                
Sbjct: 1233 TNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKL 1292

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
                +  +     +  M     L  +  K NE   ++ +  +EL M +  + + +E+L  
Sbjct: 1293 TDAKKQIKQVQKEVSVMRDEDKL--LRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNN 1350

Query: 325  SRAEKDSFLNSLSRIAQGEGT-ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
             + E+   +    R  +     E   + M   L ++EQ  V+  Q ++ + E  + +   
Sbjct: 1351 QKVEE--AIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATE 1408

Query: 384  MTQYENQ 390
            + +++ +
Sbjct: 1409 LEKWKEK 1415



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 303 EIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
           +I  EL  T+G L++++EEL++   E DS +  L    +   T++ + K    ++D+++ 
Sbjct: 719 QIKAELAKTKGELIKTKEELKKRENESDSLIQELKTSIKKIITQNQRIKELINIIDQKED 778

Query: 363 IVKLQQTIDEQREN 376
            +   Q +    EN
Sbjct: 779 TINEFQNLKSLMEN 792


>AB002376-1|BAA20832.2|  970|Homo sapiens KIAA0378 protein.
          Length = 970

 Score = 46.8 bits (106), Expect = 2e-04
 Identities = 94/493 (19%), Positives = 202/493 (40%), Gaps = 57/493 (11%)

Query: 2   RKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTE-FDNDTERLHR 60
           R   +A+  S + H  ++ D + +  +      E+   S L+ +   T+      E    
Sbjct: 341 RTRRMAEAESQVSHLEVILDQKEKENIHLRE--ELHRRSQLQPEPAKTKALQTVIEMKDT 398

Query: 61  MVAGIAENLKAKINFSLEIAKIPWL----DRDTMIKKIERLQKENSILQHKVD----ETS 112
            +A +  N++  +   +++ K   +    DR+  IK+IE  +  +  ++ K+D    E S
Sbjct: 399 KIASLERNIR-DLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELS 457

Query: 113 KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQ 172
           KKE+E      + +     + L+ + S  +   E LKE + + E    + +  +  L  +
Sbjct: 458 KKESE------LLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLR 511

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
           L++ ++      KK K L+ L      E+     +++++++  E  E+    +++  + +
Sbjct: 512 LEEKES---FLNKKTKQLQDLTE----EKGTLAGEIRDMKDMLEVKER----KINVLQKK 560

Query: 233 TEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPC 292
            E LQ ++ +++K                      L +  +        E+ R +E +  
Sbjct: 561 IENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAL-----SEKERIIERLK- 614

Query: 293 KENEPTDRE-TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK 351
           ++ E  DRE  E  +  +     L      L+    EK+S L  L   A           
Sbjct: 615 EQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHA---------SS 665

Query: 352 MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRL------EVKRLRNYD 405
           +A+  L R+ K+  L+  I++++E    +E  + +  N     R+      ++K+L    
Sbjct: 666 LASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEA 725

Query: 406 CYSKDVSYPELQTEI---LDLHLQVETLSRERTALITAAASRAL--MLERHERAADLFAR 460
            Y +D    + Q E+   L++  +VE    ++   I    S  L  M +++++ A+L   
Sbjct: 726 SYYRD-ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHN 784

Query: 461 MVRARKDLAALLD 473
               +K  A LL+
Sbjct: 785 QQLEKKKNAQLLE 797



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 53/235 (22%), Positives = 112/235 (47%), Gaps = 30/235 (12%)

Query: 22  MESRAGVAAETLGEVRVLSNLEWKTR-NTEFDNDTERLHRMVAGIAENL---KAKINFSL 77
           +E +    ++   +++   N+E  +R N EF +  ++L +  +   +     +A+++  L
Sbjct: 684 IEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLL 743

Query: 78  EIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEE 137
           EI K    +++   KKI  L  E+  L+H  D+  K  N +   H            N++
Sbjct: 744 EILKEVENEKNDKDKKIAEL--ESLTLRHMKDQNKKVANLK---H------------NQQ 786

Query: 138 LSKERAAREALKEVVASAESMLRVAR-ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR 196
           L K++ A + L+EV    +SM   ++  +I  L   L+ T+ E +  K +    +Q    
Sbjct: 787 LEKKKNA-QLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQ---S 842

Query: 197 LAIERSH-ATVKV---KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
           LA + +H A +++   K+L E  E  ++   + +SE+ A    L+   ++++K++
Sbjct: 843 LAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQ 897


>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain (1437
            AA) protein.
          Length = 1437

 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 69/355 (19%), Positives = 140/355 (39%), Gaps = 19/355 (5%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 669  REAEFQKLRR-DLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK 727

Query: 147  ALKEVVASAESMLRVARARIATLE-RQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
               + ++S    +  A+  +     R L+D  +E    K K ++ ++L+N L  +R+   
Sbjct: 728  METDDLSSNAEAISKAKGNLEKDGGRSLEDQVSEL---KTKEEEQQRLINDLTAQRARLQ 784

Query: 206  VKVKELREQAETAEQVAQSRVSEQKART---EFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
             +  E   Q +  + +       ++A T   E L+ ++ E+ K+K               
Sbjct: 785  TEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCD 844

Query: 263  XXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEEL 322
                Q +  ++    L     +   E    + N  TD   +  +EL+  +  L +  +E 
Sbjct: 845  LLREQYEEEQEGKAELQRALSKANSEVAQWRTNTETDA-IQRTEELEEAKKKLAQRLQEA 903

Query: 323  RQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQ 382
             +     ++   SL +  Q       Q+++   +LD E+          +QR  +K + +
Sbjct: 904  EEHVEAVNAKCASLEKTKQ-----RLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSE 958

Query: 383  TMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
               +YE   A L    K  R+    ++      +  E LD   Q+ETL RE   L
Sbjct: 959  WKQKYEETQAELEASQKESRSLS--TELFKVKNVYEESLD---QLETLRRENKNL 1008



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 5/108 (4%)

Query: 145  REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            +E LKE +A  E    + +A I  L   L+ T+   +IA+++  D  + V  L  + +  
Sbjct: 1167 QEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 1226

Query: 205  TVKVKELRE-----QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
                K+L       Q+E  E + +SR +E+KA+     A +  +E  K
Sbjct: 1227 INTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKK 1274



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 58/296 (19%), Positives = 126/296 (42%), Gaps = 20/296 (6%)

Query: 148 LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
           +K ++ SAE+        +AT++ + + TK E   ++ K K+LE+ +  L  E++   ++
Sbjct: 338 IKPLLKSAET-----EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQ 392

Query: 208 VK----ELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
           V+     L +  E  EQ+ ++++ + +A+ + +  +  E+E+  A               
Sbjct: 393 VQSEADSLADAEERCEQLIKNKI-QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 451

Query: 264 XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-L 322
               +    + ++  V+ E+      V     E    +  I K L   + AL  + ++ L
Sbjct: 452 LKKDIDDL-ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK-LSKEKKALQETHQQTL 509

Query: 323 RQSRAEKDSFLNSLSRI-----AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENE 377
              +AE+D  +N L++       Q +  E   ++     +D E+   KL+  +   +E+ 
Sbjct: 510 DDLQAEEDK-VNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQEST 568

Query: 378 KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
              E    Q + +L     E+  L +     +     +LQ +I +L  ++E L  E
Sbjct: 569 MDNENDKQQLDEKLEKKEFEISNLIS-KIEDEQAVEIQLQKKIKELQARIEELGEE 623



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 36/180 (20%), Positives = 77/180 (42%), Gaps = 9/180 (5%)

Query: 207 KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX 266
           K+K L + AET +++A  +   QK + E  +++   +E  + +                 
Sbjct: 337 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMV-TLLKEKNDLQLQVQS 395

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKE-NEPTDRETEIWKELQMTRGALLRSEEELRQS 325
           +  S  D   R   + + +       KE  E  + E EI  EL   +  L   E+E  + 
Sbjct: 396 EADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKL---EDECSEL 452

Query: 326 RAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTM 384
           + + D    +L+++  +   TE+    +  E+   ++ I KL +   E++  +++ +QT+
Sbjct: 453 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSK---EKKALQETHQQTL 509



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 55/254 (21%), Positives = 114/254 (44%), Gaps = 19/254 (7%)

Query: 2    RKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRM 61
            R NL+  Q  + E +A L   E    +A + L +      L   T+NT   N  ++L   
Sbjct: 1180 RANLL--QAEIEELWATLEQTERSRKIAEQELLDASERVQL-LHTQNTSLINTKKKLEND 1236

Query: 62   VAGIAENLKAKINFSL---EIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEE 118
            V+ +   ++  I  S    E AK    D   M +++++ Q  ++ L+ ++ +  ++  ++
Sbjct: 1237 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE-RMKKNLEQTVKD 1295

Query: 119  PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKA 178
                  ++     +   +++ K  A    L+  V + +     A   +   ER++K+   
Sbjct: 1296 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTY 1355

Query: 179  EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE-QKARTEFLQ 237
            + E  +K    L+ LV++L         KVK  + QAE AE+ + + +S+ +K + E  +
Sbjct: 1356 QTEEDRKNVLRLQDLVDKLQ-------AKVKSYKRQAEEAEEQSNANLSKFRKLQHELEE 1408

Query: 238  AK----VAEQEKSK 247
            A+    +AE + +K
Sbjct: 1409 AEERADIAESQVNK 1422


>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
            (1085 AA) protein.
          Length = 1085

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 85/398 (21%), Positives = 158/398 (39%), Gaps = 32/398 (8%)

Query: 70   KAKINFSLEIAKIPWLDRDTMIKKIE-RLQKENSILQHKVDETSK-----KENEEPPCHP 123
            KA I  +LE A+      +  I +I+  L +  S +  K+ E  +     K N +     
Sbjct: 683  KADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVET 742

Query: 124  VQSG-SYNYQVLNEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAE 179
            +QS      +  NE +  ++     L E+   ++ A          + +++ QLKDT+  
Sbjct: 743  MQSALDAEVRRANEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLH 802

Query: 180  FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
             + A +  +DL++   +LAI    A +   E+ E   T EQ  ++R   + A  E L + 
Sbjct: 803  LDDALRGQEDLKE---QLAIVERRANLLQAEVEELRATLEQTERAR---KLAEQELLDSN 856

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD 299
              E+ +                     QLQS     +     + R   E       +   
Sbjct: 857  --ERVQLLHTQNTSLIHTKKKLETDLMQLQS----EVEDASRDARNAEEKAKKAITDAAM 910

Query: 300  RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR 359
               E+ KE Q T   L R ++ L Q+  +    L+   ++A   G +  Q K+ T + + 
Sbjct: 911  MAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ-KLETRIREL 968

Query: 360  EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
            E ++        EQ++N +S+ + + +YE ++  L  + +  R      +D+   +LQ +
Sbjct: 969  EFELE------GEQKKNTESV-KGLRKYERRVKELTYQSEEDRKNVLRLQDL-VDKLQVK 1020

Query: 420  ILDLHLQVETLSRERTALITAAASRALMLERHERAADL 457
            +     Q E    +  A +T        LE  E  AD+
Sbjct: 1021 VKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1058



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 63/308 (20%), Positives = 127/308 (41%), Gaps = 29/308 (9%)

Query: 136 EELSKERAAREA-LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
           ++L K +   EA +KEV   AE    +  A +   +R+L+D  +E    KK   DLE  +
Sbjct: 52  DQLIKAKFQLEAKIKEVTERAEDEEEI-NAELTAKKRKLEDECSEL---KKDIDDLELTL 107

Query: 195 NRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QEKSKAVAXXX 253
            ++  E+     KVK L E+    ++       E+KA  E  Q  + + Q +   V    
Sbjct: 108 AKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLN 167

Query: 254 XXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRG 313
                        +    +++ +R VD+ER +              R+ E   +L++ + 
Sbjct: 168 KTKSKLEQQVEDLESSLEQEKKLR-VDLERNK--------------RKLE--GDLKLAQE 210

Query: 314 ALLRSEEELRQ--SRAEKDSF-LNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
           ++L  E + +Q   R +K  F    L    + E T   Q     ++ + + +I +L++ I
Sbjct: 211 SILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQ--FQKKIKELQARIEELEEEI 268

Query: 371 DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETL 430
           + +R      E+  + Y  +L  L   ++          +++  + + E L L   +E  
Sbjct: 269 EAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELN-KKREAEFLKLRRDLEEA 327

Query: 431 SRERTALI 438
           + +  A++
Sbjct: 328 TLQHEAMV 335



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 85/434 (19%), Positives = 174/434 (40%), Gaps = 35/434 (8%)

Query: 69  LKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDET----SKKENEEPPC-HP 123
           L+AKI    E A+        +  K  +L+ E S L+  +D+     +K E E+    + 
Sbjct: 61  LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 120

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARI-------ATLERQLKDT 176
           V++ +     L+E ++K    ++AL+E    A   L+    ++       + LE+Q++D 
Sbjct: 121 VKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDL 180

Query: 177 KAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFL 236
           ++  E  KK   DLE+   +L  +   A   + +L    E  +Q    R+ ++      L
Sbjct: 181 ESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL----ENDKQQLDERLKKKDFEYCQL 236

Query: 237 QAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN- 295
           Q+KV +++                      ++++ R    +          E     E  
Sbjct: 237 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 296

Query: 296 EPTDRETEIWKELQMTRGA-LLRSEEELRQSRAEKDSFLNSLSR-----IAQ-GEGTESF 348
           E     T    EL   R A  L+   +L ++  + ++ + +L +     +A+ GE  ++ 
Sbjct: 297 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNL 356

Query: 349 Q---DKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYD 405
           Q    K+  E  + + +I  L  +++   +++ ++E+     E+QL+  R + + ++   
Sbjct: 357 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQR-S 415

Query: 406 CYSKDVSYPELQTEILDLHLQVE-------TLSRERTALITAAASRALMLERHERAADLF 458
                     LQTE  +L  Q+E        LSR + A           LE   +A +  
Sbjct: 416 LSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 475

Query: 459 ARMVRARKDLAALL 472
              +++ +    LL
Sbjct: 476 GHALQSSRHDCDLL 489



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 54/270 (20%), Positives = 110/270 (40%), Gaps = 11/270 (4%)

Query: 172 QLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKA 231
           + + TK E   ++ K K+LE+ +  L  E++   ++V+   E    AE+     + + K 
Sbjct: 1   EFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLI-KAKF 59

Query: 232 RTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL-QSFRDRSIRLVDMERRRCLEYV 290
           + E    +V E+ + +                   +L +   D  + L  +E+ +     
Sbjct: 60  QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 119

Query: 291 PCKE-NEPTDRETEIWKELQMTRGALLRSEEE-LRQSRAEKDSFLNSLSRI-----AQGE 343
             K   E      E   +L   + AL  + ++ L   +AE+D  +NSL++       Q E
Sbjct: 120 KVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK-VNSLNKTKSKLEQQVE 178

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
             ES  ++     +D E+   KL+  +   +E+   +E    Q + +L     E  +L++
Sbjct: 179 DLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQS 238

Query: 404 YDCYSKDVSYPELQTEILDLHLQVETLSRE 433
                +     + Q +I +L  ++E L  E
Sbjct: 239 -KVEDEQTLGLQFQKKIKELQARIEELEEE 267



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 79/419 (18%), Positives = 168/419 (40%), Gaps = 27/419 (6%)

Query: 37  RVLSNLEWKTRNTEFDNDTE-RLHRMVAGIAENLKA--KINFSLEIAKIPWLDRDTMIKK 93
           + L +L+ +       N T+ +L + V  +  +L+   K+   LE  K   L+ D  + +
Sbjct: 151 QALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK-LEGDLKLAQ 209

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
              L  EN   + ++DE  KK++ E  C  +QS   + Q L  +  K+    + L+  + 
Sbjct: 210 ESILDLEND--KQQLDERLKKKDFEY-CQ-LQSKVEDEQTLGLQFQKKI---KELQARIE 262

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             E  +   RA  A  E+Q  D   E E   ++ ++   + +           +  +LR 
Sbjct: 263 ELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRR 322

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
             E A    ++ V+  + +     A++ EQ  +                     L S  +
Sbjct: 323 DLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 382

Query: 274 RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ--MTRGALLRSEE-ELRQSRAEKD 330
            S+        +    +  + +E   +  EI + L    T+ + L++E  EL +   EK+
Sbjct: 383 -SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKE 441

Query: 331 SFLNSLSRIAQG--EGTESFQDKMATE----------LLDREQKIVKLQQTIDEQRENEK 378
           S ++ LSR  Q   + TE  + ++  E          L         L++  +E++E + 
Sbjct: 442 SIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRHDCDLLREQYEEEQEGKA 501

Query: 379 SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            +++ +++  +++A  R + +          + +  +L   + D   QVE ++ +  +L
Sbjct: 502 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASL 560


>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
            for embryonic myosin heavy chain (SMHCE). ).
          Length = 1085

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 85/398 (21%), Positives = 158/398 (39%), Gaps = 32/398 (8%)

Query: 70   KAKINFSLEIAKIPWLDRDTMIKKIE-RLQKENSILQHKVDETSK-----KENEEPPCHP 123
            KA I  +LE A+      +  I +I+  L +  S +  K+ E  +     K N +     
Sbjct: 683  KADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVET 742

Query: 124  VQSG-SYNYQVLNEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAE 179
            +QS      +  NE +  ++     L E+   ++ A          + +++ QLKDT+  
Sbjct: 743  MQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLH 802

Query: 180  FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
             + A +  +DL++   +LAI    A +   E+ E   T EQ  ++R   + A  E L + 
Sbjct: 803  LDDALRGQEDLKE---QLAIVERRANLLQAEVEELRATLEQTERAR---KLAEQELLDSN 856

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD 299
              E+ +                     QLQS     +     + R   E       +   
Sbjct: 857  --ERVQLLHTQNTSLIHTKKKLETDLMQLQS----EVEDASRDARNAEEKAKKAITDAAM 910

Query: 300  RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR 359
               E+ KE Q T   L R ++ L Q+  +    L+   ++A   G +  Q K+ T + + 
Sbjct: 911  MAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ-KLETRIREL 968

Query: 360  EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
            E ++        EQ++N +S+ + + +YE ++  L  + +  R      +D+   +LQ +
Sbjct: 969  EFELE------GEQKKNTESV-KGLRKYERRVKELTYQSEEDRKNVLRLQDL-VDKLQVK 1020

Query: 420  ILDLHLQVETLSRERTALITAAASRALMLERHERAADL 457
            +     Q E    +  A +T        LE  E  AD+
Sbjct: 1021 VKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1058



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 86/434 (19%), Positives = 175/434 (40%), Gaps = 35/434 (8%)

Query: 69  LKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDET----SKKENEEPPC-HP 123
           L+AKI    E A+        +  K  +L+ E S L+  +D+     +K E E+    + 
Sbjct: 61  LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 120

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARI-------ATLERQLKDT 176
           V++ +     L+E ++K    ++AL+E    A   L+    ++       + LE+Q++D 
Sbjct: 121 VKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDL 180

Query: 177 KAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFL 236
           ++  E  KK   DLE+   +L  +   A   + +L    E  +Q    R+ ++      L
Sbjct: 181 ESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL----ENDKQQLDERLKKKDFEYCQL 236

Query: 237 QAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN- 295
           Q+KV +++                      ++++ R    +          E     E  
Sbjct: 237 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 296

Query: 296 EPTDRETEIWKELQMTRGA-LLRSEEELRQSRAEKDSFLNSLSR-----IAQ-GEGTESF 348
           E     T    EL   R A  L+   +L ++  + ++ + +L +     +A+ GE  ++ 
Sbjct: 297 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNL 356

Query: 349 Q---DKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYD 405
           Q    K+  E  + + +I  L  +++   +++ ++E+     E+QL+  R + + ++   
Sbjct: 357 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQR-S 415

Query: 406 CYSKDVSYPELQTEILDLHLQVE-------TLSRERTALITAAASRALMLERHERAADLF 458
                     LQTE  +L  Q+E        LSR + A           LE   +A +  
Sbjct: 416 LSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 475

Query: 459 ARMVRARKDLAALL 472
           A  +++ +    LL
Sbjct: 476 AHALQSSRHDCDLL 489



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 63/308 (20%), Positives = 127/308 (41%), Gaps = 29/308 (9%)

Query: 136 EELSKERAAREA-LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLV 194
           ++L K +   EA +KEV   AE    +  A +   +R+L+D  +E    KK   DLE  +
Sbjct: 52  DQLIKAKFQLEAKIKEVTERAEDEEEI-NAELTAKKRKLEDECSEL---KKDIDDLELTL 107

Query: 195 NRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QEKSKAVAXXX 253
            ++  E+     KVK L E+    ++       E+KA  E  Q  + + Q +   V    
Sbjct: 108 AKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLN 167

Query: 254 XXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRG 313
                        +    +++ +R VD+ER +              R+ E   +L++ + 
Sbjct: 168 KTKSKLEQQVEDLESSLEQEKKLR-VDLERNK--------------RKLE--GDLKLAQE 210

Query: 314 ALLRSEEELRQ--SRAEKDSF-LNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
           ++L  E + +Q   R +K  F    L    + E T   Q     ++ + + +I +L++ I
Sbjct: 211 SILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQ--FQKKIKELQARIEELEEEI 268

Query: 371 DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETL 430
           + +R      E+  + Y  +L  L   ++          +++  + + E L L   +E  
Sbjct: 269 EAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELN-KKREAEFLKLRRDLEEA 327

Query: 431 SRERTALI 438
           + +  A++
Sbjct: 328 TLQHEAMV 335



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 94/451 (20%), Positives = 176/451 (39%), Gaps = 26/451 (5%)

Query: 37  RVLSNLEWKTRNTEFDNDTE-RLHRMVAGIAENLKA--KINFSLEIAKIPWLDRDTMIKK 93
           + L +L+ +       N T+ +L + V  +  +L+   K+   LE  K   L+ D  + +
Sbjct: 151 QALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK-LEGDLKLAQ 209

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
              L  EN   + ++DE  KK++ E  C  +QS   + Q L  +  K+    + L+  + 
Sbjct: 210 ESILDLEND--KQQLDERLKKKDFEY-CQ-LQSKVEDEQTLGLQFQKKI---KELQARIE 262

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             E  +   RA  A  E+Q  D   E E   ++ ++   + +           +  +LR 
Sbjct: 263 ELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRR 322

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
             E A    ++ V+  + +     A++ EQ  +                     L S  +
Sbjct: 323 DLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 382

Query: 274 RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ--MTRGALLRSEE-ELRQSRAEKD 330
            S+        +    +  + +E   +  EI + L    T+ + L++E  EL +   EK+
Sbjct: 383 -SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKE 441

Query: 331 SFLNSLSRIAQG--EGTESFQDKMATELLDREQKIVKLQQT---IDEQRENEKSMEQTMT 385
           S ++ LSR  Q   + TE  + ++  E   +      LQ +    D  RE  +  ++   
Sbjct: 442 SIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKA 501

Query: 386 QYENQLAALRLEVKRLRNYDCYSKDV--SYPELQTEILDLHLQVETLSRERTALITAAAS 443
           + +  L+    EV + R    Y  D      EL+     L  +++    +  A+    AS
Sbjct: 502 ELQRALSKANSEVAQWRTK--YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCAS 559

Query: 444 RALMLERHE-RAADLFARMVRARKDLAALLD 473
                +R +    DL   + RA   LAA LD
Sbjct: 560 LEKTKQRLQGEVEDLMVDVERA-NSLAAALD 589



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 54/270 (20%), Positives = 110/270 (40%), Gaps = 11/270 (4%)

Query: 172 QLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKA 231
           + + TK E   ++ K K+LE+ +  L  E++   ++V+   E    AE+     + + K 
Sbjct: 1   EFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLI-KAKF 59

Query: 232 RTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL-QSFRDRSIRLVDMERRRCLEYV 290
           + E    +V E+ + +                   +L +   D  + L  +E+ +     
Sbjct: 60  QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 119

Query: 291 PCKE-NEPTDRETEIWKELQMTRGALLRSEEE-LRQSRAEKDSFLNSLSRI-----AQGE 343
             K   E      E   +L   + AL  + ++ L   +AE+D  +NSL++       Q E
Sbjct: 120 KVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK-VNSLNKTKSKLEQQVE 178

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
             ES  ++     +D E+   KL+  +   +E+   +E    Q + +L     E  +L++
Sbjct: 179 DLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQS 238

Query: 404 YDCYSKDVSYPELQTEILDLHLQVETLSRE 433
                +     + Q +I +L  ++E L  E
Sbjct: 239 -KVEDEQTLGLQFQKKIKELQARIEELEEE 267


>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
            embryonic myosin heavy chain. ).
          Length = 1940

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 85/398 (21%), Positives = 158/398 (39%), Gaps = 32/398 (8%)

Query: 70   KAKINFSLEIAKIPWLDRDTMIKKIE-RLQKENSILQHKVDETSK-----KENEEPPCHP 123
            KA I  +LE A+      +  I +I+  L +  S +  K+ E  +     K N +     
Sbjct: 1538 KADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVET 1597

Query: 124  VQSG-SYNYQVLNEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAE 179
            +QS      +  NE +  ++     L E+   ++ A          + +++ QLKDT+  
Sbjct: 1598 MQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLH 1657

Query: 180  FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
             + A +  +DL++   +LAI    A +   E+ E   T EQ  ++R   + A  E L + 
Sbjct: 1658 LDDALRGQEDLKE---QLAIVERRANLLQAEVEELRATLEQTERAR---KLAEQELLDSN 1711

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD 299
              E+ +                     QLQS     +     + R   E       +   
Sbjct: 1712 --ERVQLLHTQNTSLIHTKKKLETDLMQLQS----EVEDASRDARNAEEKAKKAITDAAM 1765

Query: 300  RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR 359
               E+ KE Q T   L R ++ L Q+  +    L+   ++A   G +  Q K+ T + + 
Sbjct: 1766 MAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ-KLETRIREL 1823

Query: 360  EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
            E ++        EQ++N +S+ + + +YE ++  L  + +  R      +D+   +LQ +
Sbjct: 1824 EFELE------GEQKKNTESV-KGLRKYERRVKELTYQSEEDRKNVLRLQDL-VDKLQVK 1875

Query: 420  ILDLHLQVETLSRERTALITAAASRALMLERHERAADL 457
            +     Q E    +  A +T        LE  E  AD+
Sbjct: 1876 VKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 86/434 (19%), Positives = 175/434 (40%), Gaps = 35/434 (8%)

Query: 69   LKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDET----SKKENEEPPC-HP 123
            L+AKI    E A+        +  K  +L+ E S L+  +D+     +K E E+    + 
Sbjct: 916  LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 975

Query: 124  VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARI-------ATLERQLKDT 176
            V++ +     L+E ++K    ++AL+E    A   L+    ++       + LE+Q++D 
Sbjct: 976  VKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDL 1035

Query: 177  KAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFL 236
            ++  E  KK   DLE+   +L  +   A   + +L    E  +Q    R+ ++      L
Sbjct: 1036 ESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL----ENDKQQLDERLKKKDFEYCQL 1091

Query: 237  QAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN- 295
            Q+KV +++                      ++++ R    +          E     E  
Sbjct: 1092 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 1151

Query: 296  EPTDRETEIWKELQMTRGA-LLRSEEELRQSRAEKDSFLNSLSR-----IAQ-GEGTESF 348
            E     T    EL   R A  L+   +L ++  + ++ + +L +     +A+ GE  ++ 
Sbjct: 1152 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNL 1211

Query: 349  Q---DKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYD 405
            Q    K+  E  + + +I  L  +++   +++ ++E+     E+QL+  R + + ++   
Sbjct: 1212 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQR-S 1270

Query: 406  CYSKDVSYPELQTEILDLHLQVE-------TLSRERTALITAAASRALMLERHERAADLF 458
                      LQTE  +L  Q+E        LSR + A           LE   +A +  
Sbjct: 1271 LSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 1330

Query: 459  ARMVRARKDLAALL 472
            A  +++ +    LL
Sbjct: 1331 AHALQSSRHDCDLL 1344



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 16/294 (5%)

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +K ++ SAE+        +AT++ + + TK E   ++ K K+LE+ +  L  E++   ++
Sbjct: 837  IKPLLKSAET-----EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQ 891

Query: 208  VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
            V+   E    AE+     + + K + E    +V E+ + +                   +
Sbjct: 892  VQAESENLLDAEERCDQLI-KAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 950

Query: 268  L-QSFRDRSIRLVDMERRRCLEYVPCKE-NEPTDRETEIWKELQMTRGALLRSEEE-LRQ 324
            L +   D  + L  +E+ +       K   E      E   +L   + AL  + ++ L  
Sbjct: 951  LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 1010

Query: 325  SRAEKDSFLNSLSRI-----AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
             +AE+D  +NSL++       Q E  ES  ++     +D E+   KL+  +   +E+   
Sbjct: 1011 LQAEEDK-VNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD 1069

Query: 380  MEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            +E    Q + +L     E  +L++     +     + Q +I +L  ++E L  E
Sbjct: 1070 LENDKQQLDERLKKKDFEYCQLQS-KVEDEQTLGLQFQKKIKELQARIEELEEE 1122



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 48/211 (22%), Positives = 89/211 (42%), Gaps = 22/211 (10%)

Query: 207  KVKELREQAETAEQVAQSRVSEQKARTEFL--QAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            K+K L + AET +++A  +   QK + E    +AK  E E+                   
Sbjct: 836  KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               L    +R  +L+  + +  LE    +  E  + E EI  EL   +  L   E+E  +
Sbjct: 896  SENLLDAEERCDQLIKAKFQ--LEAKIKEVTERAEDEEEINAELTAKKRKL---EDECSE 950

Query: 325  SRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKL-----------QQTIDE 372
             + + D    +L+++  +   TE+    +  EL   ++ I KL           QQ +D+
Sbjct: 951  LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 1010

Query: 373  -QRENEK--SMEQTMTQYENQLAALRLEVKR 400
             Q E +K  S+ +T ++ E Q+  L   +++
Sbjct: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 1041



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 94/451 (20%), Positives = 176/451 (39%), Gaps = 26/451 (5%)

Query: 37   RVLSNLEWKTRNTEFDNDTE-RLHRMVAGIAENLKA--KINFSLEIAKIPWLDRDTMIKK 93
            + L +L+ +       N T+ +L + V  +  +L+   K+   LE  K   L+ D  + +
Sbjct: 1006 QALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK-LEGDLKLAQ 1064

Query: 94   IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
               L  EN   + ++DE  KK++ E  C  +QS   + Q L  +  K+    + L+  + 
Sbjct: 1065 ESILDLEND--KQQLDERLKKKDFEY-CQ-LQSKVEDEQTLGLQFQKKI---KELQARIE 1117

Query: 154  SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
              E  +   RA  A  E+Q  D   E E   ++ ++   + +           +  +LR 
Sbjct: 1118 ELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRR 1177

Query: 214  QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
              E A    ++ V+  + +     A++ EQ  +                     L S  +
Sbjct: 1178 DLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 1237

Query: 274  RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ--MTRGALLRSEE-ELRQSRAEKD 330
             S+        +    +  + +E   +  EI + L    T+ + L++E  EL +   EK+
Sbjct: 1238 -SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKE 1296

Query: 331  SFLNSLSRIAQG--EGTESFQDKMATELLDREQKIVKLQQT---IDEQRENEKSMEQTMT 385
            S ++ LSR  Q   + TE  + ++  E   +      LQ +    D  RE  +  ++   
Sbjct: 1297 SIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKA 1356

Query: 386  QYENQLAALRLEVKRLRNYDCYSKDV--SYPELQTEILDLHLQVETLSRERTALITAAAS 443
            + +  L+    EV + R    Y  D      EL+     L  +++    +  A+    AS
Sbjct: 1357 ELQRALSKANSEVAQWRTK--YETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCAS 1414

Query: 444  RALMLERHE-RAADLFARMVRARKDLAALLD 473
                 +R +    DL   + RA   LAA LD
Sbjct: 1415 LEKTKQRLQGEVEDLMVDVERA-NSLAAALD 1444


>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
            protein.
          Length = 1167

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 85/398 (21%), Positives = 158/398 (39%), Gaps = 32/398 (8%)

Query: 70   KAKINFSLEIAKIPWLDRDTMIKKIE-RLQKENSILQHKVDETSK-----KENEEPPCHP 123
            KA I  +LE A+      +  I +I+  L +  S +  K+ E  +     K N +     
Sbjct: 765  KADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVET 824

Query: 124  VQSG-SYNYQVLNEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAE 179
            +QS      +  NE +  ++     L E+   ++ A          + +++ QLKDT+  
Sbjct: 825  MQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLH 884

Query: 180  FEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAK 239
             + A +  +DL++   +LAI    A +   E+ E   T EQ  ++R   + A  E L + 
Sbjct: 885  LDDALQTQEDLKE---QLAIVERRANLLQAEVEELRATLEQTERAR---KLAEQELLDSN 938

Query: 240  VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD 299
              E+ +                     QLQS     +     + R   E       +   
Sbjct: 939  --ERVQLLHTQNTSLIHTKKKLETDLMQLQS----EVEDASRDARNAEEKAKKAITDAAM 992

Query: 300  RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR 359
               E+ KE Q T   L R ++ L Q+  +    L+   ++A   G +  Q K+ T + + 
Sbjct: 993  MAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ-KLETRIREL 1050

Query: 360  EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTE 419
            E ++        EQ++N +S+ + + +YE ++  L  + +  R      +D+   +LQ +
Sbjct: 1051 EFELE------GEQKKNTESV-KGLRKYERRVKELTYQSEEDRKNVLRLQDL-VDKLQVK 1102

Query: 420  ILDLHLQVETLSRERTALITAAASRALMLERHERAADL 457
            +     Q E    +  A +T        LE  E  AD+
Sbjct: 1103 VKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1140



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 86/434 (19%), Positives = 175/434 (40%), Gaps = 35/434 (8%)

Query: 69  LKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDET----SKKENEEPPC-HP 123
           L+AKI    E A+        +  K  +L+ E S L+  +D+     +K E E+    + 
Sbjct: 143 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 202

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARI-------ATLERQLKDT 176
           V++ +     L+E ++K    ++AL+E    A   L+    ++       + LE+Q++D 
Sbjct: 203 VKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDL 262

Query: 177 KAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFL 236
           ++  E  KK   DLE+   +L  +   A   + +L    E  +Q    R+ ++      L
Sbjct: 263 ESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL----ENDKQQLDERLKKKDFEYCQL 318

Query: 237 QAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN- 295
           Q+KV +++                      ++++ R    +          E     E  
Sbjct: 319 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 378

Query: 296 EPTDRETEIWKELQMTRGA-LLRSEEELRQSRAEKDSFLNSLSR-----IAQ-GEGTESF 348
           E     T    EL   R A  L+   +L ++  + ++ + +L +     +A+ GE  ++ 
Sbjct: 379 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNL 438

Query: 349 Q---DKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYD 405
           Q    K+  E  + + +I  L  +++   +++ ++E+     E+QL+  R + + ++   
Sbjct: 439 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQR-S 497

Query: 406 CYSKDVSYPELQTEILDLHLQVE-------TLSRERTALITAAASRALMLERHERAADLF 458
                     LQTE  +L  Q+E        LSR + A           LE   +A +  
Sbjct: 498 LSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 557

Query: 459 ARMVRARKDLAALL 472
           A  +++ +    LL
Sbjct: 558 AHALQSSRHDCDLL 571



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 16/294 (5%)

Query: 148 LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
           +K ++ SAE+        +AT++ + + TK E   ++ K K+LE+ +  L  E++   ++
Sbjct: 64  IKPLLKSAET-----EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQ 118

Query: 208 VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQ 267
           V+   E    AE+     + + K + E    +V E+ + +                   +
Sbjct: 119 VQAESENLLDAEERCDQLI-KAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 177

Query: 268 L-QSFRDRSIRLVDMERRRCLEYVPCKE-NEPTDRETEIWKELQMTRGALLRSEEE-LRQ 324
           L +   D  + L  +E+ +       K   E      E   +L   + AL  + ++ L  
Sbjct: 178 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 237

Query: 325 SRAEKDSFLNSLSRI-----AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
            +AE+D  +NSL++       Q E  ES  ++     +D E+   KL+  +   +E+   
Sbjct: 238 LQAEEDK-VNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD 296

Query: 380 MEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
           +E    Q + +L     E  +L++     +     + Q +I +L  ++E L  E
Sbjct: 297 LENDKQQLDERLKKKDFEYCQLQS-KVEDEQTLGLQFQKKIKELQARIEELEEE 349



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 48/211 (22%), Positives = 89/211 (42%), Gaps = 22/211 (10%)

Query: 207 KVKELREQAETAEQVAQSRVSEQKARTEFL--QAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
           K+K L + AET +++A  +   QK + E    +AK  E E+                   
Sbjct: 63  KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 122

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
              L    +R  +L+  + +  LE    +  E  + E EI  EL   +  L   E+E  +
Sbjct: 123 SENLLDAEERCDQLIKAKFQ--LEAKIKEVTERAEDEEEINAELTAKKRKL---EDECSE 177

Query: 325 SRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKL-----------QQTIDE 372
            + + D    +L+++  +   TE+    +  EL   ++ I KL           QQ +D+
Sbjct: 178 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 237

Query: 373 -QRENEK--SMEQTMTQYENQLAALRLEVKR 400
            Q E +K  S+ +T ++ E Q+  L   +++
Sbjct: 238 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 268



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 94/451 (20%), Positives = 176/451 (39%), Gaps = 26/451 (5%)

Query: 37  RVLSNLEWKTRNTEFDNDTE-RLHRMVAGIAENLKA--KINFSLEIAKIPWLDRDTMIKK 93
           + L +L+ +       N T+ +L + V  +  +L+   K+   LE  K   L+ D  + +
Sbjct: 233 QALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK-LEGDLKLAQ 291

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
              L  EN   + ++DE  KK++ E  C  +QS   + Q L  +  K+    + L+  + 
Sbjct: 292 ESILDLEND--KQQLDERLKKKDFEY-CQ-LQSKVEDEQTLGLQFQKKI---KELQARIE 344

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             E  +   RA  A  E+Q  D   E E   ++ ++   + +           +  +LR 
Sbjct: 345 ELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRR 404

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
             E A    ++ V+  + +     A++ EQ  +                     L S  +
Sbjct: 405 DLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 464

Query: 274 RSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQ--MTRGALLRSEE-ELRQSRAEKD 330
            S+        +    +  + +E   +  EI + L    T+ + L++E  EL +   EK+
Sbjct: 465 -SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKE 523

Query: 331 SFLNSLSRIAQG--EGTESFQDKMATELLDREQKIVKLQQT---IDEQRENEKSMEQTMT 385
           S ++ LSR  Q   + TE  + ++  E   +      LQ +    D  RE  +  ++   
Sbjct: 524 SIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKA 583

Query: 386 QYENQLAALRLEVKRLRNYDCYSKDV--SYPELQTEILDLHLQVETLSRERTALITAAAS 443
           + +  L+    EV + R    Y  D      EL+     L  +++    +  A+    AS
Sbjct: 584 ELQRALSKANSEVAQWRTK--YETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCAS 641

Query: 444 RALMLERHE-RAADLFARMVRARKDLAALLD 473
                +R +    DL   + RA   LAA LD
Sbjct: 642 LEKTKQRLQGEVEDLMVDVERA-NSLAAALD 671


>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
           family member 1 protein.
          Length = 1116

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 72/372 (19%), Positives = 153/372 (41%), Gaps = 34/372 (9%)

Query: 98  QKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES 157
           ++  +ILQ +VD    +  E+     +   +   Q + EE   +      LK+++   E 
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETM--LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 571

Query: 158 MLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR-----LAIERSHATVK--VKE 210
            + V + +I  L+ QL+D + +    K++ K L+            +E + A  +  ++ 
Sbjct: 572 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIER 631

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVA--EQEKSKAVAXXXXXXXXXXXXXXXXQL 268
           L+EQ +  E+  Q  +   K   + L+ KV+  + + S+  A                  
Sbjct: 632 LKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLK 691

Query: 269 QSFRDRSIRL-VDMERRRCL--EYVPCKENE---PTDRETEIWKELQMTRGALLRSEEEL 322
           +  R +++ + ++ ++  CL  E    K +E         E+   +Q     + R ++E 
Sbjct: 692 KDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDES 751

Query: 323 RQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQ 382
            +++AE D  L  L  +               E  D+++KI +L++ + +Q +   +++ 
Sbjct: 752 SKAQAEVDRLLEILKEV-------------ENEKNDKDKKIAELERQVKDQNKKVANLKH 798

Query: 383 TMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAA 442
              Q E + +A  LE  R R  +    + S  +LQ  +     ++E L       +   A
Sbjct: 799 -KEQVEKKKSAQMLEEARRREDNL---NDSSQQLQDSLRKKDDRIEELEEALRESVQITA 854

Query: 443 SRALMLERHERA 454
            R ++L + E A
Sbjct: 855 EREMVLAQEESA 866



 Score = 44.0 bits (99), Expect = 0.001
 Identities = 75/367 (20%), Positives = 161/367 (43%), Gaps = 54/367 (14%)

Query: 87  RDTMIKKI-ERLQKEN---SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE- 141
           RD  IKK+ E LQ +       +   + T +    E   H ++S     +  N  L +E 
Sbjct: 305 RDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEM 364

Query: 142 -RAAREALKEVVASA-ESMLRVARARIATLERQLKDTKAEFEIAKK----KHKDLEQLVN 195
            R    A       A ++++ +  ++I+++ER L+D + E ++ K       ++ E+ + 
Sbjct: 365 HRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMK 424

Query: 196 RLAIERSHATV---KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
           ++ + RSH+     KV++L+E+  + E    ++  E K +   LQA++ + ++  +    
Sbjct: 425 QMEVYRSHSKFMKNKVEQLKEELSSKE----AQWEELKKKAAGLQAEIGQVKQELSRKDT 480

Query: 253 XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                         Q   F D    +  ++     E +  KE      +TE+        
Sbjct: 481 ELLALQTKLETLTNQ---FSDSKQHIEVLK-----ESLTAKEQRAAILQTEV-------- 524

Query: 313 GALLRSEEELRQSRAEKDSFLNSLSR----IAQGEGTESFQDKMATELLD-REQKIVKLQ 367
                  + LR    EK++ LN  ++    +A+ +GT++ +     ++LD +E+K+  LQ
Sbjct: 525 -------DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQ 577

Query: 368 QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
           + I+       ++++ +   E Q+++L+  VK L+  D  + D +   L+  + +    +
Sbjct: 578 KKIE-------NLQEQLRDKEKQMSSLKERVKSLQ-ADTTNTDTALTTLEEALAEKERTI 629

Query: 428 ETLSRER 434
           E L  +R
Sbjct: 630 ERLKEQR 636



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 82/393 (20%), Positives = 154/393 (39%), Gaps = 47/393 (11%)

Query: 19  LRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDN---DTERLHRMVAGIAENLKAKINF 75
           L  +E        T+  ++   + + + +  E DN   D + L   V+ +  +L  K   
Sbjct: 615 LTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEAS 674

Query: 76  SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ-------SGS 128
            L++ +       + +KK  RL+     L+ K +E  K E++    H            S
Sbjct: 675 LLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMS 734

Query: 129 YNYQVLNEEL-------SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE 181
              Q L  E+       SK +A  + L E++   E+       +IA LERQ+KD     +
Sbjct: 735 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK--K 792

Query: 182 IAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
           +A  KHK+         +E+  +   ++E R + +     +Q      + + +    ++ 
Sbjct: 793 VANLKHKE--------QVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDD----RIE 840

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
           E E+    A                Q +S R  + + V+ E    +E V         +E
Sbjct: 841 ELEE----ALRESVQITAEREMVLAQEESARTNAEKQVE-ELLMAMEKV--------KQE 887

Query: 302 TEIWK-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMAT-ELLDR 359
            E  K +L  T+ +L   E  L   RAE+   L  +  + Q     +  +K A   LL+ 
Sbjct: 888 LESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLEL 947

Query: 360 EQKIVKLQQTIDE-QRENEKSMEQTMTQYENQL 391
                K Q+ +   +RE ++ ++Q   Q +N++
Sbjct: 948 SSSKKKTQEEVAALKREKDRLVQQLKQQTQNRM 980


>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
           family member 1 protein.
          Length = 1116

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 72/372 (19%), Positives = 153/372 (41%), Gaps = 34/372 (9%)

Query: 98  QKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES 157
           ++  +ILQ +VD    +  E+     +   +   Q + EE   +      LK+++   E 
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETM--LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 571

Query: 158 MLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR-----LAIERSHATVK--VKE 210
            + V + +I  L+ QL+D + +    K++ K L+            +E + A  +  ++ 
Sbjct: 572 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIER 631

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVA--EQEKSKAVAXXXXXXXXXXXXXXXXQL 268
           L+EQ +  E+  Q  +   K   + L+ KV+  + + S+  A                  
Sbjct: 632 LKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLK 691

Query: 269 QSFRDRSIRL-VDMERRRCL--EYVPCKENE---PTDRETEIWKELQMTRGALLRSEEEL 322
           +  R +++ + ++ ++  CL  E    K +E         E+   +Q     + R ++E 
Sbjct: 692 KDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDES 751

Query: 323 RQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQ 382
            +++AE D  L  L  +               E  D+++KI +L++ + +Q +   +++ 
Sbjct: 752 SKAQAEVDRLLEILKEV-------------ENEKNDKDKKIAELERQVKDQNKKVANLKH 798

Query: 383 TMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAA 442
              Q E + +A  LE  R R  +    + S  +LQ  +     ++E L       +   A
Sbjct: 799 -KEQVEKKKSAQMLEEARRREDNL---NDSSQQLQDSLRKKDDRIEELEEALRESVQITA 854

Query: 443 SRALMLERHERA 454
            R ++L + E A
Sbjct: 855 EREMVLAQEESA 866



 Score = 44.0 bits (99), Expect = 0.001
 Identities = 75/367 (20%), Positives = 161/367 (43%), Gaps = 54/367 (14%)

Query: 87  RDTMIKKI-ERLQKEN---SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE- 141
           RD  IKK+ E LQ +       +   + T +    E   H ++S     +  N  L +E 
Sbjct: 305 RDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEM 364

Query: 142 -RAAREALKEVVASA-ESMLRVARARIATLERQLKDTKAEFEIAKK----KHKDLEQLVN 195
            R    A       A ++++ +  ++I+++ER L+D + E ++ K       ++ E+ + 
Sbjct: 365 HRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMK 424

Query: 196 RLAIERSHATV---KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
           ++ + RSH+     KV++L+E+  + E    ++  E K +   LQA++ + ++  +    
Sbjct: 425 QMEVYRSHSKFMKNKVEQLKEELSSKE----AQWEELKKKAAGLQAEIGQVKQELSRKDT 480

Query: 253 XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                         Q   F D    +  ++     E +  KE      +TE+        
Sbjct: 481 ELLALQTKLETLTNQ---FSDSKQHIEVLK-----ESLTAKEQRAAILQTEV-------- 524

Query: 313 GALLRSEEELRQSRAEKDSFLNSLSR----IAQGEGTESFQDKMATELLD-REQKIVKLQ 367
                  + LR    EK++ LN  ++    +A+ +GT++ +     ++LD +E+K+  LQ
Sbjct: 525 -------DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQ 577

Query: 368 QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
           + I+       ++++ +   E Q+++L+  VK L+  D  + D +   L+  + +    +
Sbjct: 578 KKIE-------NLQEQLRDKEKQMSSLKERVKSLQ-ADTTNTDTALTTLEEALAEKERTI 629

Query: 428 ETLSRER 434
           E L  +R
Sbjct: 630 ERLKEQR 636



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 82/393 (20%), Positives = 154/393 (39%), Gaps = 47/393 (11%)

Query: 19  LRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDN---DTERLHRMVAGIAENLKAKINF 75
           L  +E        T+  ++   + + + +  E DN   D + L   V+ +  +L  K   
Sbjct: 615 LTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEAS 674

Query: 76  SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ-------SGS 128
            L++ +       + +KK  RL+     L+ K +E  K E++    H            S
Sbjct: 675 LLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMS 734

Query: 129 YNYQVLNEEL-------SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE 181
              Q L  E+       SK +A  + L E++   E+       +IA LERQ+KD     +
Sbjct: 735 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK--K 792

Query: 182 IAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
           +A  KHK+         +E+  +   ++E R + +     +Q      + + +    ++ 
Sbjct: 793 VANLKHKE--------QVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDD----RIE 840

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
           E E+    A                Q +S R  + + V+ E    +E V         +E
Sbjct: 841 ELEE----ALRESVQITAEREMVLAQEESARTNAEKQVE-ELLMAMEKV--------KQE 887

Query: 302 TEIWK-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMAT-ELLDR 359
            E  K +L  T+ +L   E  L   RAE+   L  +  + Q     +  +K A   LL+ 
Sbjct: 888 LESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLEL 947

Query: 360 EQKIVKLQQTIDE-QRENEKSMEQTMTQYENQL 391
                K Q+ +   +RE ++ ++Q   Q +N++
Sbjct: 948 SSSKKKTQEEVAALKREKDRLVQQLKQQTQNRM 980


>BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein.
          Length = 1006

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 66/319 (20%), Positives = 137/319 (42%), Gaps = 18/319 (5%)

Query: 96  RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-REALKEVVAS 154
           R + E + L+H+    + +  +      +     + Q + ++L KE++  R  + ++ A+
Sbjct: 247 RRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAAN 306

Query: 155 AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
            E++ R A+A    L R  +D  +E   AK K ++L++ +   + +R     +  EL   
Sbjct: 307 VETLTR-AKASAEKLCRTYEDQLSE---AKIKVEELQRQLADASTQRGRLQTESGELSRL 362

Query: 215 AETAEQVAQSRVSEQKART----EFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
            E  E +  S++S  KA      E L+ ++ E+ K+K+                  Q + 
Sbjct: 363 LEEKECLI-SQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEE 421

Query: 271 FRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEELRQSRAE 328
             +    L  +  +   E    +     D  + TE  +E +      L+  EE  ++   
Sbjct: 422 EAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANA 481

Query: 329 KDSFLNSLSRIAQGEGTE-SFQDKMATEL---LDREQKIVKLQQTIDEQRENEKSMEQTM 384
           K S L       Q E  + + + + AT     LD++Q+   L++ ++E+R  E+ M++ +
Sbjct: 482 KCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQR--HLERALEERRRQEEEMQREL 539

Query: 385 TQYENQLAALRLEVKRLRN 403
              + +   L  E+ RLR+
Sbjct: 540 EAAQRESRGLGTELFRLRH 558



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 106/488 (21%), Positives = 196/488 (40%), Gaps = 38/488 (7%)

Query: 5   LIAQQNSLLE-HYAILRDMESRAG-VAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMV 62
           L  ++ +L E H   L D+++    V+A T  ++R    LE +  + E   + E+  RM 
Sbjct: 64  LTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLR----LEQQVEDLECSLEQEKKLRMD 119

Query: 63  AGIAEN-LKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV-DETSKKENEEPP 120
              A+  L+  +  + E       D+  + +K+++   E S L  +V DE       +  
Sbjct: 120 TERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKK 179

Query: 121 CHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML-----RVARARIATLERQLKD 175
              +Q+ +   + L EEL  ERAAR  +++  A A   L     R+  A  A+  ++   
Sbjct: 180 IKELQARA---EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGC 236

Query: 176 TKAEFEIAKKKHKDLEQLVNR----LAIERSHATVKVKELREQAETAEQVAQS---RVSE 228
            K E E+ + + ++LE+   R    +A  R        EL EQ ++ ++V Q      SE
Sbjct: 237 RKREAELGRLR-RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSE 295

Query: 229 QKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE 288
            +   + L A V    ++KA A                +++  + R +     +R R L+
Sbjct: 296 LRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQ-RQLADASTQRGR-LQ 353

Query: 289 YVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQG-----E 343
               + +   + +  +  +L   +    +S EELR+   E+    ++L+   Q      +
Sbjct: 354 TESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCD 413

Query: 344 GTESFQDKMATELLDREQKIVKLQQTIDEQREN-EKSMEQTMTQYEN--QLAALRL---- 396
                 ++ A    + ++ + K    + + R   E    Q   + E   +  ALRL    
Sbjct: 414 LLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAE 473

Query: 397 EVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAAD 456
           E     N  C S + +   LQTE  D+ L++E  +    AL          LE   R  +
Sbjct: 474 EGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEE 533

Query: 457 LFARMVRA 464
              R + A
Sbjct: 534 EMQRELEA 541



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 67/321 (20%), Positives = 123/321 (38%), Gaps = 15/321 (4%)

Query: 144 AREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH 203
           A++ L   +  AE  +  A A+ ++LE+     + E E    + +        L  ++ H
Sbjct: 461 AKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRH 520

Query: 204 ATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
               ++E R Q E  ++  ++   E +   TE  + +   +E  +A+             
Sbjct: 521 LERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEE 580

Query: 263 XXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE-- 319
                 Q S   +SI+ ++ + ++ LE     E +    E E   EL+ T+   ++ E  
Sbjct: 581 ISDLTDQVSLSGKSIQELE-KTKKALEGEK-SEIQAALEEAEGALELEETKTLRIQLELS 638

Query: 320 ---EELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
               E+ +  AEKD    +L R  Q    ES Q  +  E   R + +   ++   +  + 
Sbjct: 639 QVKAEVDRKLAEKDEECANLRRNHQ-RAVESLQASLDAETRARNEALRLKKKMEGDLNDL 697

Query: 377 EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTA 436
           E  +     Q     AA RL   +L+      +     E Q    +LH Q + L R  + 
Sbjct: 698 ELQLGHATRQATEAQAATRLMQAQLKE-----EQAGRDEEQRLAAELHEQAQALERRASL 752

Query: 437 LITAAASRALMLERHERAADL 457
           L          LE+ ER+  L
Sbjct: 753 LAAELEELRAALEQGERSRRL 773



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 34/160 (21%), Positives = 80/160 (50%), Gaps = 8/160 (5%)

Query: 90  MIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
           ++ + ++L+ + + L  +V+E +++  E       +    +  ++ EEL KE+     L+
Sbjct: 795 LLNQKKKLEADLAQLSGEVEEAAQERREAE--EKAKKAITDAAMMAEELKKEQDTSAHLE 852

Query: 150 EVVASAESMLRVARARIATLER-QLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
            +  + E  +R  +AR+   E+  L+  K + +  + K ++LE  ++  A ++ HA   +
Sbjct: 853 RMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELD--AEQKKHAEA-L 909

Query: 209 KELREQAETAEQVAQSRVSEQK--ARTEFLQAKVAEQEKS 246
           K +R+     +++A     ++K  AR + L  K+  + KS
Sbjct: 910 KGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKS 949


>AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,
            cardiac muscle, beta protein.
          Length = 1983

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 66/319 (20%), Positives = 137/319 (42%), Gaps = 18/319 (5%)

Query: 96   RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-REALKEVVAS 154
            R + E + L+H+    + +  +      +     + Q + ++L KE++  R  + ++ A+
Sbjct: 1224 RRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAAN 1283

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E++ R A+A    L R  +D  +E   AK K ++L++ +   + +R     +  EL   
Sbjct: 1284 VETLTR-AKASAEKLCRTYEDQLSE---AKIKVEELQRQLADASTQRGRLQTESGELSRL 1339

Query: 215  AETAEQVAQSRVSEQKART----EFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             E  E +  S++S  KA      E L+ ++ E+ K+K+                  Q + 
Sbjct: 1340 LEEKECLI-SQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEE 1398

Query: 271  FRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEELRQSRAE 328
              +    L  +  +   E    +     D  + TE  +E +      L+  EE  ++   
Sbjct: 1399 EAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANA 1458

Query: 329  KDSFLNSLSRIAQGEGTE-SFQDKMATEL---LDREQKIVKLQQTIDEQRENEKSMEQTM 384
            K S L       Q E  + + + + AT     LD++Q+   L++ ++E+R  E+ M++ +
Sbjct: 1459 KCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQR--HLERALEERRRQEEEMQREL 1516

Query: 385  TQYENQLAALRLEVKRLRN 403
               + +   L  E+ RLR+
Sbjct: 1517 EAAQRESRGLGTELFRLRH 1535



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 106/488 (21%), Positives = 196/488 (40%), Gaps = 38/488 (7%)

Query: 5    LIAQQNSLLE-HYAILRDMESRAG-VAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMV 62
            L  ++ +L E H   L D+++    V+A T  ++R    LE +  + E   + E+  RM 
Sbjct: 1041 LTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLR----LEQQVEDLECSLEQEKKLRMD 1096

Query: 63   AGIAEN-LKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV-DETSKKENEEPP 120
               A+  L+  +  + E       D+  + +K+++   E S L  +V DE       +  
Sbjct: 1097 TERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKK 1156

Query: 121  CHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML-----RVARARIATLERQLKD 175
               +Q+ +   + L EEL  ERAAR  +++  A A   L     R+  A  A+  ++   
Sbjct: 1157 IKELQARA---EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGC 1213

Query: 176  TKAEFEIAKKKHKDLEQLVNR----LAIERSHATVKVKELREQAETAEQVAQS---RVSE 228
             K E E+ + + ++LE+   R    +A  R        EL EQ ++ ++V Q      SE
Sbjct: 1214 RKREAELGRLR-RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSE 1272

Query: 229  QKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE 288
             +   + L A V    ++KA A                +++  + R +     +R R L+
Sbjct: 1273 LRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQ-RQLADASTQRGR-LQ 1330

Query: 289  YVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQG-----E 343
                + +   + +  +  +L   +    +S EELR+   E+    ++L+   Q      +
Sbjct: 1331 TESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCD 1390

Query: 344  GTESFQDKMATELLDREQKIVKLQQTIDEQREN-EKSMEQTMTQYEN--QLAALRL---- 396
                  ++ A    + ++ + K    + + R   E    Q   + E   +  ALRL    
Sbjct: 1391 LLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAE 1450

Query: 397  EVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAAD 456
            E     N  C S + +   LQTE  D+ L++E  +    AL          LE   R  +
Sbjct: 1451 EGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEE 1510

Query: 457  LFARMVRA 464
               R + A
Sbjct: 1511 EMQRELEA 1518



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 66/326 (20%), Positives = 138/326 (42%), Gaps = 26/326 (7%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EEL+  RA    L+  +A+AE+  +       ++ ++  D   + +  +    D E+  +
Sbjct: 896  EELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCH 955

Query: 196  RLAIERSHATVKVKELREQAETAEQV-AQSRVSEQKARTEFLQAK--VAEQEKSKAVAXX 252
             L   +     KVKEL E+ E  E+V A      +K   E  + K  + + + + A A  
Sbjct: 956  LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEK 1015

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                          ++ +  D S+  +  E++   E     +    D + E  +   +T+
Sbjct: 1016 EKQATENKVKNLTEEMAAL-DESVARLTKEKKALQE---AHQQALGDLQAEEDRVSALTK 1071

Query: 313  GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
             A LR E++           +  L    + E       + A   L+ + K+   Q+++ +
Sbjct: 1072 -AKLRLEQQ-----------VEDLECSLEQEKKLRMDTERAKRKLEGDLKLT--QESVAD 1117

Query: 373  QRENEKSMEQTMTQYENQLA--ALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETL 430
              ++++ +E+ + + +++L+  +LR+E ++L       K +   + + E L+  L+ E  
Sbjct: 1118 AAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQ-MQKKIKELQARAEELEEELEAERA 1176

Query: 431  SRERTALITAAASRAL--MLERHERA 454
            +R R     A A+R L  + ER E A
Sbjct: 1177 ARARVEKQRAEAARELEELSERLEEA 1202



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 67/321 (20%), Positives = 123/321 (38%), Gaps = 15/321 (4%)

Query: 144  AREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH 203
            A++ L   +  AE  +  A A+ ++LE+     + E E    + +        L  ++ H
Sbjct: 1438 AKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRH 1497

Query: 204  ATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
                ++E R Q E  ++  ++   E +   TE  + +   +E  +A+             
Sbjct: 1498 LERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEE 1557

Query: 263  XXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE-- 319
                  Q S   +SI+ ++ + ++ LE     E +    E E   EL+ T+   ++ E  
Sbjct: 1558 ISDLTDQVSLSGKSIQELE-KTKKALEGEK-SEIQAALEEAEGALELEETKTLRIQLELS 1615

Query: 320  ---EELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
                E+ +  AEKD    +L R  Q    ES Q  +  E   R + +   ++   +  + 
Sbjct: 1616 QVKAEVDRKLAEKDEECANLRRNHQ-RAVESLQASLDAETRARNEALRLKKKMEGDLNDL 1674

Query: 377  EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTA 436
            E  +     Q     AA RL   +L+      +     E Q    +LH Q + L R  + 
Sbjct: 1675 ELQLGHATRQATEAQAATRLMQAQLKE-----EQAGRDEEQRLAAELHEQAQALERRASL 1729

Query: 437  LITAAASRALMLERHERAADL 457
            L          LE+ ER+  L
Sbjct: 1730 LAAELEELRAALEQGERSRRL 1750



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 34/160 (21%), Positives = 80/160 (50%), Gaps = 8/160 (5%)

Query: 90   MIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            ++ + ++L+ + + L  +V+E +++  E       +    +  ++ EEL KE+     L+
Sbjct: 1772 LLNQKKKLEADLAQLSGEVEEAAQERREAE--EKAKKAITDAAMMAEELKKEQDTSAHLE 1829

Query: 150  EVVASAESMLRVARARIATLER-QLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
             +  + E  +R  +AR+   E+  L+  K + +  + K ++LE  ++  A ++ HA   +
Sbjct: 1830 RMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELD--AEQKKHAEA-L 1886

Query: 209  KELREQAETAEQVAQSRVSEQK--ARTEFLQAKVAEQEKS 246
            K +R+     +++A     ++K  AR + L  K+  + KS
Sbjct: 1887 KGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKS 1926


>AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,
            cardiac muscle, beta protein.
          Length = 1983

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 66/319 (20%), Positives = 137/319 (42%), Gaps = 18/319 (5%)

Query: 96   RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-REALKEVVAS 154
            R + E + L+H+    + +  +      +     + Q + ++L KE++  R  + ++ A+
Sbjct: 1224 RRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAAN 1283

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E++ R A+A    L R  +D  +E   AK K ++L++ +   + +R     +  EL   
Sbjct: 1284 VETLTR-AKASAEKLCRTYEDQLSE---AKIKVEELQRQLADASTQRGRLQTESGELSRL 1339

Query: 215  AETAEQVAQSRVSEQKART----EFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             E  E +  S++S  KA      E L+ ++ E+ K+K+                  Q + 
Sbjct: 1340 LEEKECLI-SQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEE 1398

Query: 271  FRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEELRQSRAE 328
              +    L  +  +   E    +     D  + TE  +E +      L+  EE  ++   
Sbjct: 1399 EAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANA 1458

Query: 329  KDSFLNSLSRIAQGEGTE-SFQDKMATEL---LDREQKIVKLQQTIDEQRENEKSMEQTM 384
            K S L       Q E  + + + + AT     LD++Q+   L++ ++E+R  E+ M++ +
Sbjct: 1459 KCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQR--HLERALEERRRQEEEMQREL 1516

Query: 385  TQYENQLAALRLEVKRLRN 403
               + +   L  E+ RLR+
Sbjct: 1517 EAAQRESRGLGTELFRLRH 1535



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 106/488 (21%), Positives = 196/488 (40%), Gaps = 38/488 (7%)

Query: 5    LIAQQNSLLE-HYAILRDMESRAG-VAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMV 62
            L  ++ +L E H   L D+++    V+A T  ++R    LE +  + E   + E+  RM 
Sbjct: 1041 LTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLR----LEQQVEDLECSLEQEKKLRMD 1096

Query: 63   AGIAEN-LKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV-DETSKKENEEPP 120
               A+  L+  +  + E       D+  + +K+++   E S L  +V DE       +  
Sbjct: 1097 TERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKK 1156

Query: 121  CHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML-----RVARARIATLERQLKD 175
               +Q+ +   + L EEL  ERAAR  +++  A A   L     R+  A  A+  ++   
Sbjct: 1157 IKELQARA---EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGC 1213

Query: 176  TKAEFEIAKKKHKDLEQLVNR----LAIERSHATVKVKELREQAETAEQVAQS---RVSE 228
             K E E+ + + ++LE+   R    +A  R        EL EQ ++ ++V Q      SE
Sbjct: 1214 RKREAELGRLR-RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSE 1272

Query: 229  QKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE 288
             +   + L A V    ++KA A                +++  + R +     +R R L+
Sbjct: 1273 LRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQ-RQLADASTQRGR-LQ 1330

Query: 289  YVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQG-----E 343
                + +   + +  +  +L   +    +S EELR+   E+    ++L+   Q      +
Sbjct: 1331 TESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCD 1390

Query: 344  GTESFQDKMATELLDREQKIVKLQQTIDEQREN-EKSMEQTMTQYEN--QLAALRL---- 396
                  ++ A    + ++ + K    + + R   E    Q   + E   +  ALRL    
Sbjct: 1391 LLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAE 1450

Query: 397  EVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAAD 456
            E     N  C S + +   LQTE  D+ L++E  +    AL          LE   R  +
Sbjct: 1451 EGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEE 1510

Query: 457  LFARMVRA 464
               R + A
Sbjct: 1511 EMQRELEA 1518



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 66/326 (20%), Positives = 138/326 (42%), Gaps = 26/326 (7%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EEL+  RA    L+  +A+AE+  +       ++ ++  D   + +  +    D E+  +
Sbjct: 896  EELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCH 955

Query: 196  RLAIERSHATVKVKELREQAETAEQV-AQSRVSEQKARTEFLQAK--VAEQEKSKAVAXX 252
             L   +     KVKEL E+ E  E+V A      +K   E  + K  + + + + A A  
Sbjct: 956  LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEK 1015

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                          ++ +  D S+  +  E++   E     +    D + E  +   +T+
Sbjct: 1016 EKQATENKVKNLTEEMAAL-DESVARLTKEKKALQE---AHQQALGDLQAEEDRVSALTK 1071

Query: 313  GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
             A LR E++           +  L    + E       + A   L+ + K+   Q+++ +
Sbjct: 1072 -AKLRLEQQ-----------VEDLECSLEQEKKLRMDTERAKRKLEGDLKLT--QESVAD 1117

Query: 373  QRENEKSMEQTMTQYENQLA--ALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETL 430
              ++++ +E+ + + +++L+  +LR+E ++L       K +   + + E L+  L+ E  
Sbjct: 1118 AAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQ-MQKKIKELQARAEELEEELEAERA 1176

Query: 431  SRERTALITAAASRAL--MLERHERA 454
            +R R     A A+R L  + ER E A
Sbjct: 1177 ARARVEKQRAEAARELEELSERLEEA 1202



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 67/321 (20%), Positives = 123/321 (38%), Gaps = 15/321 (4%)

Query: 144  AREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH 203
            A++ L   +  AE  +  A A+ ++LE+     + E E    + +        L  ++ H
Sbjct: 1438 AKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRH 1497

Query: 204  ATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
                ++E R Q E  ++  ++   E +   TE  + +   +E  +A+             
Sbjct: 1498 LERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEE 1557

Query: 263  XXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE-- 319
                  Q S   +SI+ ++ + ++ LE     E +    E E   EL+ T+   ++ E  
Sbjct: 1558 ISDLTDQVSLSGKSIQELE-KTKKALEGEK-SEIQAALEEAEGALELEETKTLRIQLELS 1615

Query: 320  ---EELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
                E+ +  AEKD    +L R  Q    ES Q  +  E   R + +   ++   +  + 
Sbjct: 1616 QVKAEVDRKLAEKDEECANLRRNHQ-RAVESLQASLDAETRARNEALRLKKKMEGDLNDL 1674

Query: 377  EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTA 436
            E  +     Q     AA RL   +L+      +     E Q    +LH Q + L R  + 
Sbjct: 1675 ELQLGHATRQATEAQAATRLMQAQLKE-----EQAGRDEEQRLAAELHEQAQALERRASL 1729

Query: 437  LITAAASRALMLERHERAADL 457
            L          LE+ ER+  L
Sbjct: 1730 LAAELEELRAALEQGERSRRL 1750



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 34/160 (21%), Positives = 80/160 (50%), Gaps = 8/160 (5%)

Query: 90   MIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            ++ + ++L+ + + L  +V+E +++  E       +    +  ++ EEL KE+     L+
Sbjct: 1772 LLNQKKKLEADLAQLSGEVEEAAQERREAE--EKAKKAITDAAMMAEELKKEQDTSAHLE 1829

Query: 150  EVVASAESMLRVARARIATLER-QLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
             +  + E  +R  +AR+   E+  L+  K + +  + K ++LE  ++  A ++ HA   +
Sbjct: 1830 RMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELD--AEQKKHAEA-L 1886

Query: 209  KELREQAETAEQVAQSRVSEQK--ARTEFLQAKVAEQEKS 246
            K +R+     +++A     ++K  AR + L  K+  + KS
Sbjct: 1887 KGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKS 1926


>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
          Length = 1116

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 72/372 (19%), Positives = 153/372 (41%), Gaps = 34/372 (9%)

Query: 98  QKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES 157
           ++  +ILQ +VD    +  E+     +   +   Q + EE   +      LK+++   E 
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETM--LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 571

Query: 158 MLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR-----LAIERSHATVK--VKE 210
            + V + +I  L+ QL+D + +    K++ K L+            +E + A  +  ++ 
Sbjct: 572 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIER 631

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVA--EQEKSKAVAXXXXXXXXXXXXXXXXQL 268
           L+EQ +  E+  Q  +   K   + L+ KV+  + + S+  A                  
Sbjct: 632 LKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLK 691

Query: 269 QSFRDRSIRL-VDMERRRCL--EYVPCKENE---PTDRETEIWKELQMTRGALLRSEEEL 322
           +  R +++ + ++ ++  CL  E    K +E         E+   +Q     + R ++E 
Sbjct: 692 KDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDES 751

Query: 323 RQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQ 382
            +++AE D  L  L  +               E  D+++KI +L++ + +Q +   +++ 
Sbjct: 752 SKAQAEVDRLLEILKEV-------------ENEKNDKDKKIAELERQVKDQNKKVANLKH 798

Query: 383 TMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAA 442
              Q E + +A  LE  R R  +    + S  +LQ  +     ++E L       +   A
Sbjct: 799 -KEQVEKKKSAQMLEEARRREDNL---NDSSQQLQDSLRKKDDRIEELEEALRESVQITA 854

Query: 443 SRALMLERHERA 454
            R ++L + E A
Sbjct: 855 EREMVLAQEESA 866



 Score = 44.0 bits (99), Expect = 0.001
 Identities = 75/367 (20%), Positives = 161/367 (43%), Gaps = 54/367 (14%)

Query: 87  RDTMIKKI-ERLQKEN---SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE- 141
           RD  IKK+ E LQ +       +   + T +    E   H ++S     +  N  L +E 
Sbjct: 305 RDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEM 364

Query: 142 -RAAREALKEVVASA-ESMLRVARARIATLERQLKDTKAEFEIAKK----KHKDLEQLVN 195
            R    A       A ++++ +  ++I+++ER L+D + E ++ K       ++ E+ + 
Sbjct: 365 HRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMK 424

Query: 196 RLAIERSHATV---KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
           ++ + RSH+     KV++L+E+  + E    ++  E K +   LQA++ + ++  +    
Sbjct: 425 QMEVYRSHSKFMKNKVEQLKEELSSKE----AQWEELKKKAAGLQAEIGQVKQELSRKDT 480

Query: 253 XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                         Q   F D    +  ++     E +  KE      +TE+        
Sbjct: 481 ELLALQTKLETLTNQ---FSDSKQHIEVLK-----ESLTAKEQRAAILQTEV-------- 524

Query: 313 GALLRSEEELRQSRAEKDSFLNSLSR----IAQGEGTESFQDKMATELLD-REQKIVKLQ 367
                  + LR    EK++ LN  ++    +A+ +GT++ +     ++LD +E+K+  LQ
Sbjct: 525 -------DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQ 577

Query: 368 QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
           + I+       ++++ +   E Q+++L+  VK L+  D  + D +   L+  + +    +
Sbjct: 578 KKIE-------NLQEQLRDKEKQMSSLKERVKSLQ-ADTTNTDTALTTLEEALAEKERTI 629

Query: 428 ETLSRER 434
           E L  +R
Sbjct: 630 ERLKEQR 636



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 82/393 (20%), Positives = 154/393 (39%), Gaps = 47/393 (11%)

Query: 19  LRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDN---DTERLHRMVAGIAENLKAKINF 75
           L  +E        T+  ++   + + + +  E DN   D + L   V+ +  +L  K   
Sbjct: 615 LTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEAS 674

Query: 76  SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ-------SGS 128
            L++ +       + +KK  RL+     L+ K +E  K E++    H            S
Sbjct: 675 LLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMS 734

Query: 129 YNYQVLNEEL-------SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE 181
              Q L  E+       SK +A  + L E++   E+       +IA LERQ+KD     +
Sbjct: 735 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK--K 792

Query: 182 IAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
           +A  KHK+         +E+  +   ++E R + +     +Q      + + +    ++ 
Sbjct: 793 VANLKHKE--------QVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDD----RIE 840

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
           E E+    A                Q +S R  + + V+ E    +E V         +E
Sbjct: 841 ELEE----ALRESVQITAEREMVLAQEESARTNAEKQVE-ELLMAMEKV--------KQE 887

Query: 302 TEIWK-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMAT-ELLDR 359
            E  K +L  T+ +L   E  L   RAE+   L  +  + Q     +  +K A   LL+ 
Sbjct: 888 LESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLEL 947

Query: 360 EQKIVKLQQTIDE-QRENEKSMEQTMTQYENQL 391
                K Q+ +   +RE ++ ++Q   Q +N++
Sbjct: 948 SSSKKKTQEEVAALKREKDRLVQQLKQQTQNRM 980


>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
          Length = 1088

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 72/372 (19%), Positives = 153/372 (41%), Gaps = 34/372 (9%)

Query: 98  QKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES 157
           ++  +ILQ +VD    +  E+     +   +   Q + EE   +      LK+++   E 
Sbjct: 486 EQRAAILQTEVDALRLRLEEKETM--LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 543

Query: 158 MLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR-----LAIERSHATVK--VKE 210
            + V + +I  L+ QL+D + +    K++ K L+            +E + A  +  ++ 
Sbjct: 544 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIER 603

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVA--EQEKSKAVAXXXXXXXXXXXXXXXXQL 268
           L+EQ +  E+  Q  +   K   + L+ KV+  + + S+  A                  
Sbjct: 604 LKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLK 663

Query: 269 QSFRDRSIRL-VDMERRRCL--EYVPCKENE---PTDRETEIWKELQMTRGALLRSEEEL 322
           +  R +++ + ++ ++  CL  E    K +E         E+   +Q     + R ++E 
Sbjct: 664 KDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDES 723

Query: 323 RQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQ 382
            +++AE D  L  L  +               E  D+++KI +L++ + +Q +   +++ 
Sbjct: 724 SKAQAEVDRLLEILKEV-------------ENEKNDKDKKIAELERQVKDQNKKVANLKH 770

Query: 383 TMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAA 442
              Q E + +A  LE  R R  +    + S  +LQ  +     ++E L       +   A
Sbjct: 771 -KEQVEKKKSAQMLEEARRREDNL---NDSSQQLQDSLRKKDDRIEELEEALRESVQITA 826

Query: 443 SRALMLERHERA 454
            R ++L + E A
Sbjct: 827 EREMVLAQEESA 838



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 78/423 (18%), Positives = 175/423 (41%), Gaps = 35/423 (8%)

Query: 87  RDTMIKKI-ERLQKEN---SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE- 141
           RD  IKK+ E LQ +       +   + T +    E   H ++S     +  N  L +E 
Sbjct: 305 RDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEM 364

Query: 142 -RAAREALKEVVASA-ESMLRVARARIATLERQLKDTKAEFEIAKK----KHKDLEQLVN 195
            R    A       A ++++ +  ++I+++ER L+D + E ++ K       ++ E+ + 
Sbjct: 365 HRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMK 424

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           ++ + RSH+     ++ +  +   +   + +   + + E L  + ++ ++   V      
Sbjct: 425 QMEVYRSHSKFMKNKIGQVKQELSR-KDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 483

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDR-ETEIWKEL----QM 310
                      ++ + R R      M  ++  +     E + T   E    K++    + 
Sbjct: 484 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 543

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSL-SRIAQGEGTESFQDKMATELLDREQKIVKLQQT 369
               L +  E L++   +K+  ++SL  R+   +   +  D   T L   E+ + + ++T
Sbjct: 544 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL---EEALAEKERT 600

Query: 370 ID---EQRE-NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
           I+   EQR+ +E+  ++ +  Y+  L  L+ +V  L+       D+S  E +  +LDL  
Sbjct: 601 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG------DLS--EKEASLLDLKE 652

Query: 426 QVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRIDPPPFEDIA 485
              +L+   + L   +  + L +   ++  +      + +K   A L+ R  P   + I 
Sbjct: 653 HASSLA--SSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQ 710

Query: 486 HAE 488
           H E
Sbjct: 711 HLE 713



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 82/393 (20%), Positives = 154/393 (39%), Gaps = 47/393 (11%)

Query: 19  LRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDN---DTERLHRMVAGIAENLKAKINF 75
           L  +E        T+  ++   + + + +  E DN   D + L   V+ +  +L  K   
Sbjct: 587 LTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEAS 646

Query: 76  SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ-------SGS 128
            L++ +       + +KK  RL+     L+ K +E  K E++    H            S
Sbjct: 647 LLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMS 706

Query: 129 YNYQVLNEEL-------SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE 181
              Q L  E+       SK +A  + L E++   E+       +IA LERQ+KD     +
Sbjct: 707 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK--K 764

Query: 182 IAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
           +A  KHK+         +E+  +   ++E R + +     +Q      + + +    ++ 
Sbjct: 765 VANLKHKE--------QVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDD----RIE 812

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
           E E+    A                Q +S R  + + V+ E    +E V         +E
Sbjct: 813 ELEE----ALRESVQITAEREMVLAQEESARTNAEKQVE-ELLMAMEKV--------KQE 859

Query: 302 TEIWK-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMAT-ELLDR 359
            E  K +L  T+ +L   E  L   RAE+   L  +  + Q     +  +K A   LL+ 
Sbjct: 860 LESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLEL 919

Query: 360 EQKIVKLQQTIDE-QRENEKSMEQTMTQYENQL 391
                K Q+ +   +RE ++ ++Q   Q +N++
Sbjct: 920 SSSKKKTQEEVAALKREKDRLVQQLKQQTQNRM 952


>AB053469-1|BAC54108.1|  720|Homo sapiens ELKS gamma protein.
          Length = 720

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 90/451 (19%), Positives = 184/451 (40%), Gaps = 34/451 (7%)

Query: 24  SRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIP 83
           S A     +L + R  + ++ +T+  E   + + L + V      L + +N S++    P
Sbjct: 134 SMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMN-SIKTFWSP 192

Query: 84  WLDRDTMIKKIER----LQKEN-SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEEL 138
            L ++  ++K E     + KE   ++Q +    + +   E     +   +   Q + EE 
Sbjct: 193 ELKKERALRKDEASKITIWKEQYRVVQEENQVDALRLRLEEKETMLNKKTKQIQDMAEEK 252

Query: 139 SKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR-- 196
             +      LK+++   E  + V + +I  L+ QL+D + +    K++ K L+       
Sbjct: 253 GTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTD 312

Query: 197 ---LAIERSHATVK--VKELREQAETAEQVAQSRVSEQKARTEFLQAKVA--EQEKSKAV 249
                +E + A  +  ++ L+EQ +  E+  Q  +   K   + L+ KV+  + + S+  
Sbjct: 313 TALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKE 372

Query: 250 AXXXXXXXXXXXXXXXXQLQSFRDRSIRL-VDMERRRCL--EYVPCKENE---PTDRETE 303
           A                  +  R +++ + ++ ++  CL  E    K +E         E
Sbjct: 373 ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPE 432

Query: 304 IWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKI 363
           +   +Q     + R ++E  +++AE D  L  L  +   E  ++ +DK   EL     + 
Sbjct: 433 MSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEV---ENEKNDKDKKIAELESLTSRQ 489

Query: 364 VKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDL 423
           VK Q   +++  N K  EQ     E + +A  LE  R R  +    + S  +LQ  +   
Sbjct: 490 VKDQ---NKKVANLKHKEQV----EKKKSAQMLEEARRREDNL---NDSSQQLQDSLRKK 539

Query: 424 HLQVETLSRERTALITAAASRALMLERHERA 454
             ++E L       +   A R ++L + E A
Sbjct: 540 DDRIEELEEALRESVQITAEREMVLAQEESA 570


>AB053468-1|BAC54107.1|  992|Homo sapiens ELKS beta protein.
          Length = 992

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 77/372 (20%), Positives = 153/372 (41%), Gaps = 30/372 (8%)

Query: 98  QKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES 157
           ++  +ILQ +VD    +  E+     +   +   Q + EE   +      LK+++   E 
Sbjct: 486 EQRAAILQTEVDALRLRLEEKETM--LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 543

Query: 158 MLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR-----LAIERSHATVK--VKE 210
            + V + +I  L+ QL+D + +    K++ K L+            +E + A  +  ++ 
Sbjct: 544 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIER 603

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVA--EQEKSKAVAXXXXXXXXXXXXXXXXQL 268
           L+EQ +  E+  Q  +   K   + L+ KV+  + + S+  A                  
Sbjct: 604 LKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLK 663

Query: 269 QSFRDRSIRL-VDMERRRCL--EYVPCKENE---PTDRETEIWKELQMTRGALLRSEEEL 322
           +  R +++ + ++ ++  CL  E    K +E         E+   +Q     + R ++E 
Sbjct: 664 KDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDES 723

Query: 323 RQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQ 382
            +++AE D  L  L  +   E  ++ +DK   EL     + VK Q   +++  N K  EQ
Sbjct: 724 SKAQAEVDRLLEILKEV---ENEKNDKDKKIAELESLTSRQVKDQ---NKKVANLKHKEQ 777

Query: 383 TMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAA 442
                E + +A  LE  R R  +    + S  +LQ  +     ++E L       +   A
Sbjct: 778 V----EKKKSAQMLEEARRREDNL---NDSSQQLQDSLRKKDDRIEELEEALRESVQITA 830

Query: 443 SRALMLERHERA 454
            R ++L + E A
Sbjct: 831 EREMVLAQEESA 842



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 78/423 (18%), Positives = 175/423 (41%), Gaps = 35/423 (8%)

Query: 87  RDTMIKKI-ERLQKEN---SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE- 141
           RD  IKK+ E LQ +       +   + T +    E   H ++S     +  N  L +E 
Sbjct: 305 RDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEM 364

Query: 142 -RAAREALKEVVASA-ESMLRVARARIATLERQLKDTKAEFEIAKK----KHKDLEQLVN 195
            R    A       A ++++ +  ++I+++ER L+D + E ++ K       ++ E+ + 
Sbjct: 365 HRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMK 424

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           ++ + RSH+     ++ +  +   +   + +   + + E L  + ++ ++   V      
Sbjct: 425 QMEVYRSHSKFMKNKIGQVKQELSR-KDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 483

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDR-ETEIWKEL----QM 310
                      ++ + R R      M  ++  +     E + T   E    K++    + 
Sbjct: 484 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 543

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSL-SRIAQGEGTESFQDKMATELLDREQKIVKLQQT 369
               L +  E L++   +K+  ++SL  R+   +   +  D   T L   E+ + + ++T
Sbjct: 544 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL---EEALAEKERT 600

Query: 370 ID---EQRE-NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
           I+   EQR+ +E+  ++ +  Y+  L  L+ +V  L+       D+S  E +  +LDL  
Sbjct: 601 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG------DLS--EKEASLLDLKE 652

Query: 426 QVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRIDPPPFEDIA 485
              +L+   + L   +  + L +   ++  +      + +K   A L+ R  P   + I 
Sbjct: 653 HASSLA--SSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQ 710

Query: 486 HAE 488
           H E
Sbjct: 711 HLE 713


>AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein.
          Length = 2010

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 66/319 (20%), Positives = 137/319 (42%), Gaps = 18/319 (5%)

Query: 96   RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-REALKEVVAS 154
            R + E + L+H+    + +  +      +     + Q + ++L KE++  R  + ++ A+
Sbjct: 1251 RRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAAN 1310

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E++ R A+A    L R  +D  +E   AK K ++L++ +   + +R     +  EL   
Sbjct: 1311 VETLTR-AKASAEKLCRTYEDQLSE---AKIKVEELQRQLADASTQRGRLQTESGELSRL 1366

Query: 215  AETAEQVAQSRVSEQKART----EFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQS 270
             E  E +  S++S  KA      E L+ ++ E+ K+K+                  Q + 
Sbjct: 1367 LEEKECLI-SQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEE 1425

Query: 271  FRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEELRQSRAE 328
              +    L  +  +   E    +     D  + TE  +E +      L+  EE  ++   
Sbjct: 1426 EAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANA 1485

Query: 329  KDSFLNSLSRIAQGEGTE-SFQDKMATEL---LDREQKIVKLQQTIDEQRENEKSMEQTM 384
            K S L       Q E  + + + + AT     LD++Q+   L++ ++E+R  E+ M++ +
Sbjct: 1486 KCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQR--HLERALEERRRQEEEMQREL 1543

Query: 385  TQYENQLAALRLEVKRLRN 403
               + +   L  E+ RLR+
Sbjct: 1544 EAAQRESRGLGTELFRLRH 1562



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 67/326 (20%), Positives = 138/326 (42%), Gaps = 26/326 (7%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EEL+  RA    L+  +A+AE+  +       ++ ++  D   + +  +    D E+  +
Sbjct: 923  EELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCH 982

Query: 196  RLAIERSHATVKVKELREQAETAEQV-AQSRVSEQKARTEFLQAK--VAEQEKSKAVAXX 252
             L   +     KVKEL E+ E  E+V A      +K   E  + K  + + E + A A  
Sbjct: 983  LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEK 1042

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                          ++ +  D S+  +  E++   E     +    D + E  +   +T+
Sbjct: 1043 EKQATENKVKNLTEEMAAL-DESVARLTKEKKALQE---AHQQALGDLQAEEDRVSALTK 1098

Query: 313  GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
             A LR E++           +  L    + E       + A   L+ + K+   Q+++ +
Sbjct: 1099 -AKLRLEQQ-----------VEDLECSLEQEKKLRMDTERAKRKLEGDLKLT--QESVAD 1144

Query: 373  QRENEKSMEQTMTQYENQLA--ALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETL 430
              ++++ +E+ + + +++L+  +LR+E ++L       K +   + + E L+  L+ E  
Sbjct: 1145 AAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQ-MQKKIKELQARAEELEEELEAERA 1203

Query: 431  SRERTALITAAASRAL--MLERHERA 454
            +R R     A A+R L  + ER E A
Sbjct: 1204 ARARVEKQRAEAARELEELSERLEEA 1229



 Score = 41.9 bits (94), Expect = 0.005
 Identities = 106/488 (21%), Positives = 196/488 (40%), Gaps = 38/488 (7%)

Query: 5    LIAQQNSLLE-HYAILRDMESRAG-VAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMV 62
            L  ++ +L E H   L D+++    V+A T  ++R    LE +  + E   + E+  RM 
Sbjct: 1068 LTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLR----LEQQVEDLECSLEQEKKLRMD 1123

Query: 63   AGIAEN-LKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV-DETSKKENEEPP 120
               A+  L+  +  + E       D+  + +K+++   E S L  +V DE       +  
Sbjct: 1124 TERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKK 1183

Query: 121  CHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML-----RVARARIATLERQLKD 175
               +Q+ +   + L EEL  ERAAR  +++  A A   L     R+  A  A+  ++   
Sbjct: 1184 IKELQARA---EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGC 1240

Query: 176  TKAEFEIAKKKHKDLEQLVNR----LAIERSHATVKVKELREQAETAEQVAQS---RVSE 228
             K E E+ + + ++LE+   R    +A  R        EL EQ ++ ++V Q      SE
Sbjct: 1241 RKREAELGRLR-RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSE 1299

Query: 229  QKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE 288
             +   + L A V    ++KA A                +++  + R +     +R R L+
Sbjct: 1300 LRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQ-RQLADASTQRGR-LQ 1357

Query: 289  YVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQG-----E 343
                + +   + +  +  +L   +    +S EELR+   E+    ++L+   Q      +
Sbjct: 1358 TESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCD 1417

Query: 344  GTESFQDKMATELLDREQKIVKLQQTIDEQREN-EKSMEQTMTQYEN--QLAALRL---- 396
                  ++ A    + ++ + K    + + R   E    Q   + E   +  ALRL    
Sbjct: 1418 LLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAE 1477

Query: 397  EVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAAD 456
            E     N  C S + +   LQTE  D+ L++E  +    AL          LE   R  +
Sbjct: 1478 EGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEE 1537

Query: 457  LFARMVRA 464
               R + A
Sbjct: 1538 EMQRELEA 1545



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 67/321 (20%), Positives = 123/321 (38%), Gaps = 15/321 (4%)

Query: 144  AREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH 203
            A++ L   +  AE  +  A A+ ++LE+     + E E    + +        L  ++ H
Sbjct: 1465 AKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRH 1524

Query: 204  ATVKVKELREQAETAEQVAQSRVSEQKAR-TEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
                ++E R Q E  ++  ++   E +   TE  + +   +E  +A+             
Sbjct: 1525 LERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEE 1584

Query: 263  XXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE-- 319
                  Q S   +SI+ ++ + ++ LE     E +    E E   EL+ T+   ++ E  
Sbjct: 1585 ISDLTDQVSLSGKSIQELE-KTKKALEGEK-SEIQAALEEAEGALELEETKTLRIQLELS 1642

Query: 320  ---EELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQREN 376
                E+ +  AEKD    +L R  Q    ES Q  +  E   R + +   ++   +  + 
Sbjct: 1643 QVKAEVDRKLAEKDEECANLRRNHQ-RAVESLQASLDAETRARNEALRLKKKMEGDLNDL 1701

Query: 377  EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTA 436
            E  +     Q     AA RL   +L+      +     E Q    +LH Q + L R  + 
Sbjct: 1702 ELQLGHATRQATEAQAATRLMQAQLKE-----EQAGRDEEQRLAAELHEQAQALERRASL 1756

Query: 437  LITAAASRALMLERHERAADL 457
            L          LE+ ER+  L
Sbjct: 1757 LAAELEELRAALEQGERSRRL 1777



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 34/160 (21%), Positives = 80/160 (50%), Gaps = 8/160 (5%)

Query: 90   MIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALK 149
            ++ + ++L+ + + L  +V+E +++  E       +    +  ++ EEL KE+     L+
Sbjct: 1799 LLNQKKKLEADLAQLSGEVEEAAQERREAE--EKAKKAITDAAMMAEELKKEQDTSAHLE 1856

Query: 150  EVVASAESMLRVARARIATLER-QLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
             +  + E  +R  +AR+   E+  L+  K + +  + K ++LE  ++  A ++ HA   +
Sbjct: 1857 RMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELD--AEQKKHAEA-L 1913

Query: 209  KELREQAETAEQVAQSRVSEQK--ARTEFLQAKVAEQEKS 246
            K +R+     +++A     ++K  AR + L  K+  + KS
Sbjct: 1914 KGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKS 1953


>AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.
          Length = 1003

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 77/372 (20%), Positives = 153/372 (41%), Gaps = 30/372 (8%)

Query: 98  QKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES 157
           ++  +ILQ +VD    +  E+     +   +   Q + EE   +      LK+++   E 
Sbjct: 497 EQRAAILQTEVDALRLRLEEKETM--LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 554

Query: 158 MLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR-----LAIERSHATVK--VKE 210
            + V + +I  L+ QL+D + +    K++ K L+            +E + A  +  ++ 
Sbjct: 555 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIER 614

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVA--EQEKSKAVAXXXXXXXXXXXXXXXXQL 268
           L+EQ +  E+  Q  +   K   + L+ KV+  + + S+  A                  
Sbjct: 615 LKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLK 674

Query: 269 QSFRDRSIRL-VDMERRRCL--EYVPCKENE---PTDRETEIWKELQMTRGALLRSEEEL 322
           +  R +++ + ++ ++  CL  E    K +E         E+   +Q     + R ++E 
Sbjct: 675 KDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDES 734

Query: 323 RQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQ 382
            +++AE D  L  L  +   E  ++ +DK   EL     + VK Q   +++  N K  EQ
Sbjct: 735 SKAQAEVDRLLEILKEV---ENEKNDKDKKIAELESLTSRQVKDQ---NKKVANLKHKEQ 788

Query: 383 TMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAA 442
                E + +A  LE  R R  +    + S  +LQ  +     ++E L       +   A
Sbjct: 789 V----EKKKSAQMLEEARRREDNL---NDSSQQLQDSLRKKDDRIEELEEALRESVQITA 841

Query: 443 SRALMLERHERA 454
            R ++L + E A
Sbjct: 842 EREMVLAQEESA 853



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 78/423 (18%), Positives = 175/423 (41%), Gaps = 35/423 (8%)

Query: 87  RDTMIKKI-ERLQKEN---SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE- 141
           RD  IKK+ E LQ +       +   + T +    E   H ++S     +  N  L +E 
Sbjct: 316 RDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEM 375

Query: 142 -RAAREALKEVVASA-ESMLRVARARIATLERQLKDTKAEFEIAKK----KHKDLEQLVN 195
            R    A       A ++++ +  ++I+++ER L+D + E ++ K       ++ E+ + 
Sbjct: 376 HRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMK 435

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           ++ + RSH+     ++ +  +   +   + +   + + E L  + ++ ++   V      
Sbjct: 436 QMEVYRSHSKFMKNKIGQVKQELSR-KDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 494

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDR-ETEIWKEL----QM 310
                      ++ + R R      M  ++  +     E + T   E    K++    + 
Sbjct: 495 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 554

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSL-SRIAQGEGTESFQDKMATELLDREQKIVKLQQT 369
               L +  E L++   +K+  ++SL  R+   +   +  D   T L   E+ + + ++T
Sbjct: 555 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL---EEALAEKERT 611

Query: 370 ID---EQRE-NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
           I+   EQR+ +E+  ++ +  Y+  L  L+ +V  L+       D+S  E +  +LDL  
Sbjct: 612 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG------DLS--EKEASLLDLKE 663

Query: 426 QVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRIDPPPFEDIA 485
              +L+   + L   +  + L +   ++  +      + +K   A L+ R  P   + I 
Sbjct: 664 HASSLA--SSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQ 721

Query: 486 HAE 488
           H E
Sbjct: 722 HLE 724


>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
            chain protein.
          Length = 1934

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 67/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 1167 REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 1225

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
              L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +R+   
Sbjct: 1226 LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQRAKLQ 1281

Query: 206  VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 1340

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                 Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 1341 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
            EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 1401 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 1458

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
              +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 1515



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 70/353 (19%), Positives = 141/353 (39%), Gaps = 36/353 (10%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 991  KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 1049

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
            +   +L  +       + +L    +  ++             +R+ +++A    LQ K+ 
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
            E + ++                   +L+S   R +  +            C+      RE
Sbjct: 1110 ELQ-ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKRE 1168

Query: 302  TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
             E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228

Query: 354  TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
             ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288

Query: 402  RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
            R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 1289 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 1339



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 27/111 (24%), Positives = 58/111 (52%), Gaps = 7/111 (6%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1609 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1668

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
            + +  +   R++   +++ELR   EQ E + ++A   + E   R + L ++
Sbjct: 1669 ENI-AIVERRNNLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQ 1718



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 53/287 (18%), Positives = 124/287 (43%), Gaps = 15/287 (5%)

Query: 166  IATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVK----ELREQAETAEQV 221
            +A+++ +    K   E ++ + K+LE+ +  L  E++   ++V+     L +  E  +Q+
Sbjct: 849  MASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 908

Query: 222  AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
             ++++ + +A+ + +  ++ ++E+  A                   +    + ++  V+ 
Sbjct: 909  IKNKI-QLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDIDDL-ELTLAKVEK 966

Query: 282  ERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEE-LRQSRAEKDSFLNSLSRI- 339
            E+      V     E    + EI  +L   + AL  + ++ L   +AE+D  +N+L++  
Sbjct: 967  EKHATENKVKNLTEEMAGLD-EIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLTKAK 1024

Query: 340  ----AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
                 Q +  E   ++     +D E+   KL+  +   +E+   +E    Q + +L    
Sbjct: 1025 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 1084

Query: 396  LEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAA 442
             E+  L N     +     +LQ ++ +L  ++E L  E  A  TA A
Sbjct: 1085 FELNAL-NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 82/441 (18%), Positives = 168/441 (38%), Gaps = 40/441 (9%)

Query: 43   EWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS 102
            EWK +  E  ++ E   +    ++  L     F L+ A       +  ++ +E  ++EN 
Sbjct: 1455 EWKQKYEESQSELESSQKEARSLSTEL-----FKLKNAY------EESLEHLETFKRENK 1503

Query: 103  ILQHKV-DETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML-R 160
             LQ ++ D T +  +     H ++      +    EL      + AL+E  AS E    +
Sbjct: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMEL------QSALEEAEASLEHEEGK 1557

Query: 161  VARARI------ATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
            + RA++      A +ER+L +   E E AK+ H    ++V+ L       T      R +
Sbjct: 1558 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL---RVVDSLQTSLDAET----RSRNE 1610

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
            A   ++  +  ++E + +        AE +K                      +++  D 
Sbjct: 1611 ALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSLLKDTQIQLDDAVRANDDL 1667

Query: 275  SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLN 334
               +  +ERR  L+    +E      +TE  +  ++    L+ + E ++   ++  S +N
Sbjct: 1668 KENIAIVERRNNLQ-AELEELRAVVEQTE--RSRKLADRELIETSERVQLLHSQNTSLIN 1724

Query: 335  SLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAA 393
               ++ A     ++  ++   E  + E+K  K         E  K  + T    E     
Sbjct: 1725 QKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1784

Query: 394  LRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHE- 452
            +   +K L++    ++ ++    + ++  L  +V  L  E  A     A     + + E 
Sbjct: 1785 MEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSER 1844

Query: 453  RAADLFARMVRARKDLAALLD 473
            R  +L  +    RK+L  L D
Sbjct: 1845 RIKELTYQTEEDRKNLLRLQD 1865



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1734 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1792

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1793 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1842

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1843 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1890

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1891 NLSKFRKVQHELDEAEERADIAESQVNK 1918


>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain
           (1151 AA) protein.
          Length = 1151

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 67/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87  RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
           R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 383 REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 441

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
             L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +R+   
Sbjct: 442 LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQRAKLQ 497

Query: 206 VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
            +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 498 TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 556

Query: 262 XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 557 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 616

Query: 320 EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
           EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 617 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 674

Query: 376 NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
             +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 675 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 731



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 68/373 (18%), Positives = 154/373 (41%), Gaps = 28/373 (7%)

Query: 66  AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
           AE  K   +   E  ++      +  ++ E  +K  S+LQ K D   + + E+      +
Sbjct: 59  AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 118

Query: 126 SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                 Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    K+
Sbjct: 119 ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KR 168

Query: 186 KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
              DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 169 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 228

Query: 245 KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEI 304
           +   V                 +    +++ +R+ D+ER +             + + ++
Sbjct: 229 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM-DLERAK----------RKLEGDLKL 277

Query: 305 WKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIV 364
            +E  M    L   +++L +   +KD  LN+L+  A+ E  ++   ++  +L + + +I 
Sbjct: 278 TQESIMD---LENDKQQLEERLKKKDFELNALN--ARIEDEQALGSQLQKKLKELQARIE 332

Query: 365 KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP-ELQTEILDL 423
           +L++ ++ +R     +E+  +    +L  +   ++          +++   E + + +  
Sbjct: 333 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 392

Query: 424 HLQVETLSRERTA 436
            L+  TL  E TA
Sbjct: 393 DLEEATLQHEATA 405



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 26/111 (23%), Positives = 56/111 (50%), Gaps = 6/111 (5%)

Query: 135 NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
           NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 825 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 884

Query: 192 QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
           + +  +    +    +++ELR   EQ E + ++A   + E   R + L ++
Sbjct: 885 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLADEELIETSERVQLLHSQ 935



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 70/353 (19%), Positives = 140/353 (39%), Gaps = 36/353 (10%)

Query: 132 QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
           ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 207 KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 265

Query: 192 QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
           +   +L  +       + +L    +  E+             +R+ +++A    LQ K+ 
Sbjct: 266 RAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQLQKKLK 325

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
           E + ++                   +L+S   R +  +             +      RE
Sbjct: 326 ELQ-ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 384

Query: 302 TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
            E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 385 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 444

Query: 354 TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
            ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 445 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 504

Query: 402 RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
           R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 505 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 555



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 68/340 (20%), Positives = 137/340 (40%), Gaps = 24/340 (7%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L   L +E+  R  L+      E  L++ +  I  LE   +  +   E  KKK  +L  L
Sbjct: 250 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLE---ERLKKKDFELNAL 306

Query: 194 VNRLAIER---SHATVKVKELREQAETAEQVAQ----SRVSEQKARTEFLQAKVAEQEKS 246
             R+  E+   S    K+KEL+ + E  E+  +    +R   +K R++ L  ++ E  + 
Sbjct: 307 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD-LSRELEEISER 365

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
              A                + Q  R R +    ++       +  K     D   E+ +
Sbjct: 366 LEEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGE 421

Query: 307 ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR-EQKIVK 365
           ++   +    + E+E  + + E D   +++ +I + +      +KM   L D+  +   K
Sbjct: 422 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKMCRTLEDQMNEHRSK 478

Query: 366 LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
            ++T  ++  N+ + ++   Q EN   + +L+ K           ++Y + Q E L   L
Sbjct: 479 AEET--QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQL 535

Query: 426 QVETLSRERT--ALITAAASRALMLERHERAADLFARMVR 463
           + E  ++     AL +A     L+ E++E   +  A + R
Sbjct: 536 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 575



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 71/330 (21%), Positives = 130/330 (39%), Gaps = 38/330 (11%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKEN----EEPPCHPVQSGSYNYQVLNEELSKERAA 144
            T + K++   +E+  L+H   ET K+EN    EE      Q GS    +   EL K R  
Sbjct: 695  TELFKLKNAYEES--LEHL--ETFKRENKNLQEEISDLTEQLGSSGKTI--HELEKVRKQ 748

Query: 145  REA----LKEVVASAESMLRVARARIATLERQLKDTKAEFEIA-KKKHKDLEQLV-NRLA 198
             EA    L+  +  AE+ L     +I   + +    KAE E    +K +++EQ   N L 
Sbjct: 749  LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 808

Query: 199  IERSHATVKVKELREQAET--AEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
            +  S  T    E R + E    ++  +  ++E + +        AE +K           
Sbjct: 809  VVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSL 865

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       +++  D    +  +ERR  L     +E      +TE  +  ++    L+
Sbjct: 866  LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLADEELI 923

Query: 317  RSEEELRQSRAEKDSFLNSLSRI------AQGEGTESFQD---------KMATELLDREQ 361
             + E ++   ++  S +N   ++       Q E  E+ Q+         K  T+     +
Sbjct: 924  ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE 983

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ K Q T       +K+MEQT+   +++L
Sbjct: 984  ELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1013



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 951  SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1009

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1010 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1059

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1060 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1107

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1108 NLSKFRKVQHELDEAEERADIAESQVNK 1135


>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
            protein.
          Length = 1935

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 67/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 1167 REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 1225

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
              L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +R+   
Sbjct: 1226 LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQRAKLQ 1281

Query: 206  VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 1340

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                 Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 1341 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
            EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 1401 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 1458

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
              +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 1515



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 68/373 (18%), Positives = 154/373 (41%), Gaps = 28/373 (7%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
            AE  K   +   E  ++      +  ++ E  +K  S+LQ K D   + + E+      +
Sbjct: 843  AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                  Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    K+
Sbjct: 903  ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KR 952

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
               DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 953  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 1012

Query: 245  KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEI 304
            +   V                 +    +++ +R+ D+ER +             + + ++
Sbjct: 1013 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM-DLERAK----------RKLEGDLKL 1061

Query: 305  WKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIV 364
             +E  M    L   +++L +   +KD  LN+L+  A+ E  ++   ++  +L + + +I 
Sbjct: 1062 TQESIMD---LENDKQQLDERLKKKDFELNALN--ARIEDEQALGSQLQKKLKELQARIE 1116

Query: 365  KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP-ELQTEILDL 423
            +L++ ++ +R     +E+  +    +L  +   ++          +++   E + + +  
Sbjct: 1117 ELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1176

Query: 424  HLQVETLSRERTA 436
             L+  TL  E TA
Sbjct: 1177 DLEEATLQHEATA 1189



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1609 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1668

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
            + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++
Sbjct: 1669 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 70/340 (20%), Positives = 137/340 (40%), Gaps = 24/340 (7%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L   L +E+  R  L+      E  L++ +  I  LE    D +   E  KKK  +L  L
Sbjct: 1034 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN---DKQQLDERLKKKDFELNAL 1090

Query: 194  VNRLAIER---SHATVKVKELREQAETAEQVAQS----RVSEQKARTEFLQAKVAEQEKS 246
              R+  E+   S    K+KEL+ + E  E+  +S    R   +K R++ L  ++ E  + 
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSD-LSRELEEISER 1149

Query: 247  KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
               A                + Q  R R +    ++       +  K     D   E+ +
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGE 1205

Query: 307  ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR-EQKIVK 365
            ++   +    + E+E  + + E D   +++ +I + +      +KM   L D+  +   K
Sbjct: 1206 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKMCRTLEDQMNEHRSK 1262

Query: 366  LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
             ++T  ++  N+ + ++   Q EN   + +L+ K           ++Y + Q E L   L
Sbjct: 1263 AEET--QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQL 1319

Query: 426  QVETLSRERT--ALITAAASRALMLERHERAADLFARMVR 463
            + E  ++     AL +A     L+ E++E   +  A + R
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 1359



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 69/353 (19%), Positives = 140/353 (39%), Gaps = 36/353 (10%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 991  KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 1049

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
            +   +L  +       + +L    +  ++             +R+ +++A    LQ K+ 
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
            E + ++                   +L+S   R +  +             +      RE
Sbjct: 1110 ELQ-ARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168

Query: 302  TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
             E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228

Query: 354  TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
             ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288

Query: 402  RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
            R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 1289 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 1339



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 71/330 (21%), Positives = 130/330 (39%), Gaps = 38/330 (11%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKEN----EEPPCHPVQSGSYNYQVLNEELSKERAA 144
            T + K++   +E+  L+H   ET K+EN    EE      Q GS    +   EL K R  
Sbjct: 1479 TELFKLKNAYEES--LEHL--ETFKRENKNLQEEISDLTEQLGSSGKTI--HELEKVRKQ 1532

Query: 145  REA----LKEVVASAESMLRVARARIATLERQLKDTKAEFEIA-KKKHKDLEQLV-NRLA 198
             EA    L+  +  AE+ L     +I   + +    KAE E    +K +++EQ   N L 
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 1592

Query: 199  IERSHATVKVKELREQAET--AEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
            +  S  T    E R + E    ++  +  ++E + +        AE +K           
Sbjct: 1593 VVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSL 1649

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       +++  D    +  +ERR  L     +E      +TE  +  ++    L+
Sbjct: 1650 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELI 1707

Query: 317  RSEEELRQSRAEKDSFLNSLSRI------AQGEGTESFQD---------KMATELLDREQ 361
             + E ++   ++  S +N   ++       Q E  E+ Q+         K  T+     +
Sbjct: 1708 ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE 1767

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ K Q T       +K+MEQT+   +++L
Sbjct: 1768 ELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1793

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1794 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1843

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1844 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1891

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1892 NLSKFRKVQHELDEAEERADIAESQVNK 1919


>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
            protein.
          Length = 1935

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 67/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 1167 REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 1225

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
              L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +R+   
Sbjct: 1226 LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQRAKLQ 1281

Query: 206  VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 1340

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                 Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 1341 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
            EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 1401 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 1458

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
              +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 1515



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 68/373 (18%), Positives = 154/373 (41%), Gaps = 28/373 (7%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
            AE  K   +   E  ++      +  ++ E  +K  S+LQ K D   + + E+      +
Sbjct: 843  AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                  Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    K+
Sbjct: 903  ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KR 952

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
               DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 953  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 1012

Query: 245  KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEI 304
            +   V                 +    +++ +R+ D+ER +             + + ++
Sbjct: 1013 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM-DLERAK----------RKLEGDLKL 1061

Query: 305  WKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIV 364
             +E  M    L   +++L +   +KD  LN+L+  A+ E  ++   ++  +L + + +I 
Sbjct: 1062 TQESIMD---LENDKQQLDERLKKKDFELNALN--ARIEDEQALGSQLQKKLKELQARIE 1116

Query: 365  KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP-ELQTEILDL 423
            +L++ ++ +R     +E+  +    +L  +   ++          +++   E + + +  
Sbjct: 1117 ELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1176

Query: 424  HLQVETLSRERTA 436
             L+  TL  E TA
Sbjct: 1177 DLEEATLQHEATA 1189



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1609 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1668

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
            + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++
Sbjct: 1669 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 70/340 (20%), Positives = 137/340 (40%), Gaps = 24/340 (7%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L   L +E+  R  L+      E  L++ +  I  LE    D +   E  KKK  +L  L
Sbjct: 1034 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN---DKQQLDERLKKKDFELNAL 1090

Query: 194  VNRLAIER---SHATVKVKELREQAETAEQVAQS----RVSEQKARTEFLQAKVAEQEKS 246
              R+  E+   S    K+KEL+ + E  E+  +S    R   +K R++ L  ++ E  + 
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSD-LSRELEEISER 1149

Query: 247  KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
               A                + Q  R R +    ++       +  K     D   E+ +
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGE 1205

Query: 307  ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR-EQKIVK 365
            ++   +    + E+E  + + E D   +++ +I + +      +KM   L D+  +   K
Sbjct: 1206 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKMCRTLEDQMNEHRSK 1262

Query: 366  LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
             ++T  ++  N+ + ++   Q EN   + +L+ K           ++Y + Q E L   L
Sbjct: 1263 AEET--QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQL 1319

Query: 426  QVETLSRERT--ALITAAASRALMLERHERAADLFARMVR 463
            + E  ++     AL +A     L+ E++E   +  A + R
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 1359



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 69/353 (19%), Positives = 140/353 (39%), Gaps = 36/353 (10%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 991  KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 1049

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
            +   +L  +       + +L    +  ++             +R+ +++A    LQ K+ 
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
            E + ++                   +L+S   R +  +             +      RE
Sbjct: 1110 ELQ-ARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168

Query: 302  TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
             E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228

Query: 354  TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
             ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288

Query: 402  RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
            R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 1289 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 1339



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 71/330 (21%), Positives = 130/330 (39%), Gaps = 38/330 (11%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKEN----EEPPCHPVQSGSYNYQVLNEELSKERAA 144
            T + K++   +E+  L+H   ET K+EN    EE      Q GS    +   EL K R  
Sbjct: 1479 TELFKLKNAYEES--LEHL--ETFKRENKNLQEEISDLTEQLGSSGKTI--HELEKVRKQ 1532

Query: 145  REA----LKEVVASAESMLRVARARIATLERQLKDTKAEFEIA-KKKHKDLEQLV-NRLA 198
             EA    L+  +  AE+ L     +I   + +    KAE E    +K +++EQ   N L 
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 1592

Query: 199  IERSHATVKVKELREQAET--AEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
            +  S  T    E R + E    ++  +  ++E + +        AE +K           
Sbjct: 1593 VVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSL 1649

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       +++  D    +  +ERR  L     +E      +TE  +  ++    L+
Sbjct: 1650 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELI 1707

Query: 317  RSEEELRQSRAEKDSFLNSLSRI------AQGEGTESFQD---------KMATELLDREQ 361
             + E ++   ++  S +N   ++       Q E  E+ Q+         K  T+     +
Sbjct: 1708 ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE 1767

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ K Q T       +K+MEQT+   +++L
Sbjct: 1768 ELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1793

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1794 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1843

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1844 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1891

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1892 NLSKFRKVQHELDEAEERADIAESQVNK 1919


>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
            cardiac muscle, beta protein.
          Length = 1935

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 67/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 1167 REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 1225

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
              L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +R+   
Sbjct: 1226 LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQRAKLQ 1281

Query: 206  VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 1340

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                 Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 1341 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
            EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 1401 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 1458

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
              +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 1515



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1609 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1668

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
            + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++
Sbjct: 1669 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 68/373 (18%), Positives = 154/373 (41%), Gaps = 28/373 (7%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
            AE  K   +   E  ++      +  ++ E  +K  S+LQ K D   + + E+      +
Sbjct: 843  AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                  Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    K+
Sbjct: 903  ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KR 952

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
               DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 953  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 1012

Query: 245  KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEI 304
            +   V                 +    +++ +R+ D+ER +             + + ++
Sbjct: 1013 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM-DLERAK----------RKLEGDLKL 1061

Query: 305  WKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIV 364
             +E  M    L   +++L +   +KD  LN+L+  A+ E  ++   ++  +L + + +I 
Sbjct: 1062 TQESIMD---LENDKQQLDERLKKKDFELNALN--ARIEDEQALGSQLQKKLKELQARIE 1116

Query: 365  KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP-ELQTEILDL 423
            +L++ ++ +R     +E+  +    +L  +   ++          +++   E + + +  
Sbjct: 1117 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1176

Query: 424  HLQVETLSRERTA 436
             L+  TL  E TA
Sbjct: 1177 DLEEATLQHEATA 1189



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 69/340 (20%), Positives = 137/340 (40%), Gaps = 24/340 (7%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L   L +E+  R  L+      E  L++ +  I  LE    D +   E  KKK  +L  L
Sbjct: 1034 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN---DKQQLDERLKKKDFELNAL 1090

Query: 194  VNRLAIER---SHATVKVKELREQAETAEQVAQ----SRVSEQKARTEFLQAKVAEQEKS 246
              R+  E+   S    K+KEL+ + E  E+  +    +R   +K R++ L  ++ E  + 
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD-LSRELEEISER 1149

Query: 247  KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
               A                + Q  R R +    ++       +  K     D   E+ +
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGE 1205

Query: 307  ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR-EQKIVK 365
            ++   +    + E+E  + + E D   +++ +I + +      +KM   L D+  +   K
Sbjct: 1206 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKMCRTLEDQMNEHRSK 1262

Query: 366  LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
             ++T  ++  N+ + ++   Q EN   + +L+ K           ++Y + Q E L   L
Sbjct: 1263 AEET--QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQL 1319

Query: 426  QVETLSRERT--ALITAAASRALMLERHERAADLFARMVR 463
            + E  ++     AL +A     L+ E++E   +  A + R
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 1359



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 69/353 (19%), Positives = 140/353 (39%), Gaps = 36/353 (10%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 991  KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 1049

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
            +   +L  +       + +L    +  ++             +R+ +++A    LQ K+ 
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
            E + ++                   +L+S   R +  +             +      RE
Sbjct: 1110 ELQ-ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168

Query: 302  TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
             E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228

Query: 354  TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
             ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288

Query: 402  RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
            R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 1289 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 1339



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 71/330 (21%), Positives = 130/330 (39%), Gaps = 38/330 (11%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKEN----EEPPCHPVQSGSYNYQVLNEELSKERAA 144
            T + K++   +E+  L+H   ET K+EN    EE      Q GS    +   EL K R  
Sbjct: 1479 TELFKLKNAYEES--LEHL--ETFKRENKNLQEEISDLTEQLGSSGKTI--HELEKVRKQ 1532

Query: 145  REA----LKEVVASAESMLRVARARIATLERQLKDTKAEFEIA-KKKHKDLEQLV-NRLA 198
             EA    L+  +  AE+ L     +I   + +    KAE E    +K +++EQ   N L 
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 1592

Query: 199  IERSHATVKVKELREQAET--AEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
            +  S  T    E R + E    ++  +  ++E + +        AE +K           
Sbjct: 1593 VVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSL 1649

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       +++  D    +  +ERR  L     +E      +TE  +  ++    L+
Sbjct: 1650 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELI 1707

Query: 317  RSEEELRQSRAEKDSFLNSLSRI------AQGEGTESFQD---------KMATELLDREQ 361
             + E ++   ++  S +N   ++       Q E  E+ Q+         K  T+     +
Sbjct: 1708 ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE 1767

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ K Q T       +K+MEQT+   +++L
Sbjct: 1768 ELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1793

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1794 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1843

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1844 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1891

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1892 NLSKFRKVQHELDEAEERADIAESQVNK 1919


>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
            cardiac muscle, beta protein.
          Length = 1935

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 67/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 1167 REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 1225

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
              L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +R+   
Sbjct: 1226 LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQRAKLQ 1281

Query: 206  VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 1340

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                 Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 1341 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
            EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 1401 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 1458

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
              +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 1515



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1609 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1668

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
            + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++
Sbjct: 1669 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 68/373 (18%), Positives = 154/373 (41%), Gaps = 28/373 (7%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
            AE  K   +   E  ++      +  ++ E  +K  S+LQ K D   + + E+      +
Sbjct: 843  AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                  Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    K+
Sbjct: 903  ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KR 952

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
               DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 953  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 1012

Query: 245  KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEI 304
            +   V                 +    +++ +R+ D+ER +             + + ++
Sbjct: 1013 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM-DLERAK----------RKLEGDLKL 1061

Query: 305  WKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIV 364
             +E  M    L   +++L +   +KD  LN+L+  A+ E  ++   ++  +L + + +I 
Sbjct: 1062 TQESIMD---LENDKQQLDERLKKKDFELNALN--ARIEDEQALGSQLQKKLKELQARIE 1116

Query: 365  KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP-ELQTEILDL 423
            +L++ ++ +R     +E+  +    +L  +   ++          +++   E + + +  
Sbjct: 1117 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1176

Query: 424  HLQVETLSRERTA 436
             L+  TL  E TA
Sbjct: 1177 DLEEATLQHEATA 1189



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 69/340 (20%), Positives = 137/340 (40%), Gaps = 24/340 (7%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L   L +E+  R  L+      E  L++ +  I  LE    D +   E  KKK  +L  L
Sbjct: 1034 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN---DKQQLDERLKKKDFELNAL 1090

Query: 194  VNRLAIER---SHATVKVKELREQAETAEQVAQ----SRVSEQKARTEFLQAKVAEQEKS 246
              R+  E+   S    K+KEL+ + E  E+  +    +R   +K R++ L  ++ E  + 
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD-LSRELEEISER 1149

Query: 247  KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
               A                + Q  R R +    ++       +  K     D   E+ +
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGE 1205

Query: 307  ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR-EQKIVK 365
            ++   +    + E+E  + + E D   +++ +I + +      +KM   L D+  +   K
Sbjct: 1206 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKMCRTLEDQMNEHRSK 1262

Query: 366  LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
             ++T  ++  N+ + ++   Q EN   + +L+ K           ++Y + Q E L   L
Sbjct: 1263 AEET--QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQL 1319

Query: 426  QVETLSRERT--ALITAAASRALMLERHERAADLFARMVR 463
            + E  ++     AL +A     L+ E++E   +  A + R
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 1359



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 69/353 (19%), Positives = 140/353 (39%), Gaps = 36/353 (10%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 991  KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 1049

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
            +   +L  +       + +L    +  ++             +R+ +++A    LQ K+ 
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
            E + ++                   +L+S   R +  +             +      RE
Sbjct: 1110 ELQ-ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168

Query: 302  TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
             E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228

Query: 354  TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
             ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288

Query: 402  RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
            R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 1289 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 1339



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 71/330 (21%), Positives = 130/330 (39%), Gaps = 38/330 (11%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKEN----EEPPCHPVQSGSYNYQVLNEELSKERAA 144
            T + K++   +E+  L+H   ET K+EN    EE      Q GS    +   EL K R  
Sbjct: 1479 TELFKLKNAYEES--LEHL--ETFKRENKNLQEEISDLTEQLGSSGKTI--HELEKVRKQ 1532

Query: 145  REA----LKEVVASAESMLRVARARIATLERQLKDTKAEFEIA-KKKHKDLEQLV-NRLA 198
             EA    L+  +  AE+ L     +I   + +    KAE E    +K +++EQ   N L 
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 1592

Query: 199  IERSHATVKVKELREQAET--AEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
            +  S  T    E R + E    ++  +  ++E + +        AE +K           
Sbjct: 1593 VVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSL 1649

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       +++  D    +  +ERR  L     +E      +TE  +  ++    L+
Sbjct: 1650 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELI 1707

Query: 317  RSEEELRQSRAEKDSFLNSLSRI------AQGEGTESFQD---------KMATELLDREQ 361
             + E ++   ++  S +N   ++       Q E  E+ Q+         K  T+     +
Sbjct: 1708 ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE 1767

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ K Q T       +K+MEQT+   +++L
Sbjct: 1768 ELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1793

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1794 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1843

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1844 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1891

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1892 NLSKFRKVQHELDEAEERADIAESQVNK 1919


>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
            cardiac muscle, beta protein.
          Length = 1935

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 67/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 1167 REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 1225

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
              L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +R+   
Sbjct: 1226 LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQRAKLQ 1281

Query: 206  VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 1340

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                 Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 1341 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
            EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 1401 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 1458

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
              +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 1515



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1609 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1668

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
            + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++
Sbjct: 1669 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 68/373 (18%), Positives = 154/373 (41%), Gaps = 28/373 (7%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
            AE  K   +   E  ++      +  ++ E  +K  S+LQ K D   + + E+      +
Sbjct: 843  AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                  Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    K+
Sbjct: 903  ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KR 952

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
               DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 953  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 1012

Query: 245  KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEI 304
            +   V                 +    +++ +R+ D+ER +             + + ++
Sbjct: 1013 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM-DLERAK----------RKLEGDLKL 1061

Query: 305  WKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIV 364
             +E  M    L   +++L +   +KD  LN+L+  A+ E  ++   ++  +L + + +I 
Sbjct: 1062 TQESIMD---LENDKQQLDERLKKKDFELNALN--ARIEDEQALGSQLQKKLKELQARIE 1116

Query: 365  KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP-ELQTEILDL 423
            +L++ ++ +R     +E+  +    +L  +   ++          +++   E + + +  
Sbjct: 1117 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1176

Query: 424  HLQVETLSRERTA 436
             L+  TL  E TA
Sbjct: 1177 DLEEATLQHEATA 1189



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 69/340 (20%), Positives = 137/340 (40%), Gaps = 24/340 (7%)

Query: 134  LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
            L   L +E+  R  L+      E  L++ +  I  LE    D +   E  KKK  +L  L
Sbjct: 1034 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN---DKQQLDERLKKKDFELNAL 1090

Query: 194  VNRLAIER---SHATVKVKELREQAETAEQVAQ----SRVSEQKARTEFLQAKVAEQEKS 246
              R+  E+   S    K+KEL+ + E  E+  +    +R   +K R++ L  ++ E  + 
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD-LSRELEEISER 1149

Query: 247  KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
               A                + Q  R R +    ++       +  K     D   E+ +
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGE 1205

Query: 307  ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR-EQKIVK 365
            ++   +    + E+E  + + E D   +++ +I + +      +KM   L D+  +   K
Sbjct: 1206 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKMCRTLEDQMNEHRSK 1262

Query: 366  LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
             ++T  ++  N+ + ++   Q EN   + +L+ K           ++Y + Q E L   L
Sbjct: 1263 AEET--QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQL 1319

Query: 426  QVETLSRERT--ALITAAASRALMLERHERAADLFARMVR 463
            + E  ++     AL +A     L+ E++E   +  A + R
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 1359



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 69/353 (19%), Positives = 140/353 (39%), Gaps = 36/353 (10%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 991  KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 1049

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
            +   +L  +       + +L    +  ++             +R+ +++A    LQ K+ 
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
            E + ++                   +L+S   R +  +             +      RE
Sbjct: 1110 ELQ-ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168

Query: 302  TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
             E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228

Query: 354  TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
             ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288

Query: 402  RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
            R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 1289 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 1339



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 71/330 (21%), Positives = 130/330 (39%), Gaps = 38/330 (11%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKEN----EEPPCHPVQSGSYNYQVLNEELSKERAA 144
            T + K++   +E+  L+H   ET K+EN    EE      Q GS    +   EL K R  
Sbjct: 1479 TELFKLKNAYEES--LEHL--ETFKRENKNLQEEISDLTEQLGSSGKTI--HELEKVRKQ 1532

Query: 145  REA----LKEVVASAESMLRVARARIATLERQLKDTKAEFEIA-KKKHKDLEQLV-NRLA 198
             EA    L+  +  AE+ L     +I   + +    KAE E    +K +++EQ   N L 
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 1592

Query: 199  IERSHATVKVKELREQAET--AEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
            +  S  T    E R + E    ++  +  ++E + +        AE +K           
Sbjct: 1593 VVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSL 1649

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       +++  D    +  +ERR  L     +E      +TE  +  ++    L+
Sbjct: 1650 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELI 1707

Query: 317  RSEEELRQSRAEKDSFLNSLSRI------AQGEGTESFQD---------KMATELLDREQ 361
             + E ++   ++  S +N   ++       Q E  E+ Q+         K  T+     +
Sbjct: 1708 ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE 1767

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ K Q T       +K+MEQT+   +++L
Sbjct: 1768 ELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1793

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1794 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1843

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1844 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1891

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1892 NLSKFRKVQHELDEAEERADIAESQVNK 1919


>BC064528-1|AAH64528.1|  762|Homo sapiens coiled-coil domain
           containing 21 protein.
          Length = 762

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 71/287 (24%), Positives = 119/287 (41%), Gaps = 26/287 (9%)

Query: 161 VARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ 220
           V   R+  L+R+    +A+F    +K + L +    L  + S + V+V+ +RE  + A Q
Sbjct: 379 VCLLRLQELQRENTFLRAQFA---QKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQ 435

Query: 221 VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
                V +Q+ R +     +   +K                      L+ +      L D
Sbjct: 436 KHSEEVKKQEERVKGRDKHINNLKKK----CQKESEQNREKQQRIETLERYLADLPTLED 491

Query: 281 MERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE---EELRQSRAEKDSFLNSL 336
            +++ + L+    K  E  ++ TE+   L+ T+      E   E LRQ  AE  S  +SL
Sbjct: 492 HQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSL 551

Query: 337 S-----RIAQGEGTESFQDKMATELLDREQKIV-KLQQTIDEQRENEKSMEQTMTQYENQ 390
                     GEG E   +       D  QKIV K QQ +D+ R   +S+EQ + Q E  
Sbjct: 552 QDKQSVEETSGEGPEVEMESWQKRY-DSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGT 610

Query: 391 LAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
             ALR E +R        +D +  +L+T + +L +Q + L  +   L
Sbjct: 611 SQALREEAQR--------RDSALQQLRTAVKELSVQNQDLIEKNLTL 649



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 28/176 (15%), Positives = 74/176 (42%), Gaps = 4/176 (2%)

Query: 294 ENEPTDRETEIWKELQMTRGALLRSEEELRQSRAE---KDSFLNSLSRIAQGEGTESFQD 350
           E + +  E E+    +  + AL +  EE+++       +D  +N+L +  Q E  ++ + 
Sbjct: 413 EKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREK 472

Query: 351 KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           +   E L+R    +   +   +Q +  K  E   T+ + ++  L   ++  +   C  K+
Sbjct: 473 QQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAI-CREKE 531

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARK 466
           +    L+    +      +L  +++   T+     + +E  ++  D   ++V  ++
Sbjct: 532 IQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQ 587


>BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open reading
           frame 60 protein.
          Length = 1107

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 92/447 (20%), Positives = 175/447 (39%), Gaps = 36/447 (8%)

Query: 37  RVLSNLEWKTRNTE--FDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKK- 93
           +++ + E K    +  ++ + + L R     AE+L+A      ++ K  +  ++ +++K 
Sbjct: 210 KLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRK-EFQGQEAILRKT 268

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           I +L+ E  ++Q +      K  +      +     N QVL ++L   +    AL     
Sbjct: 269 IGKLKTELQMVQDEAGSLLDKCQKLQTALAIAEN--NVQVLQKQLDDAKEGEMALLSKHK 326

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             ES L  AR R+      L    +   + +      E  +  L  E+S    ++ +L E
Sbjct: 327 EVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEE 386

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA-VAXXXXXXXXXXXXXXXXQLQSFR 272
           +        QS   EQK +   L+ KV E ++++                    QL    
Sbjct: 387 ERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAH 446

Query: 273 DRSIRLVDMERRRCLEYVPC-----KENEPTDRETEIWKE---LQMTRGALLRSEEELRQ 324
            +++  +  +    +E V       K+    D E +  K+   L+  +  L +  E L++
Sbjct: 447 SKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKE 506

Query: 325 SRAEKDSFLNS--------LSRIAQGEGTE-----SFQDKMATELLDREQKIVK--LQQT 369
              +K +  N         + +  QG G+      S QD    E L  E  + K  L++T
Sbjct: 507 VLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQ--ERLQNELDLTKDSLKET 564

Query: 370 IDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVE 428
            D     E  +EQ   Q+E  +AA++ E K   +   +  ++ + E L+ E   L    E
Sbjct: 565 KDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLR---E 621

Query: 429 TLSRERTALITAAASRALMLERHERAA 455
            L  +      +A S+ L L+  E+ A
Sbjct: 622 ELRLQHEEDKKSAMSQLLQLKDREKNA 648


>AL451139-16|CAI15849.2|  434|Homo sapiens coiled-coil domain
           containing 21 protein.
          Length = 434

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 71/287 (24%), Positives = 119/287 (41%), Gaps = 26/287 (9%)

Query: 161 VARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ 220
           V   R+  L+R+    +A+F    +K + L +    L  + S + V+V+ +RE  + A Q
Sbjct: 52  VCLLRLQELQRENTFLRAQFA---QKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQ 108

Query: 221 VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
                V +Q+ R +     +   +K                      L+ +      L D
Sbjct: 109 KHSEEVKKQEERVKGRDKHINNLKKK----CQKESEQNREKQQRIETLERYLADLPTLED 164

Query: 281 MERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE---EELRQSRAEKDSFLNSL 336
            +++ + L+    K  E  ++ TE+   L+ T+      E   E LRQ  AE  S  +SL
Sbjct: 165 HQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSL 224

Query: 337 S-----RIAQGEGTESFQDKMATELLDREQKIV-KLQQTIDEQRENEKSMEQTMTQYENQ 390
                     GEG E   +       D  QKIV K QQ +D+ R   +S+EQ + Q E  
Sbjct: 225 QDKQSVEETSGEGPEVEMESWQKRY-DSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGT 283

Query: 391 LAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
             ALR E +R        +D +  +L+T + +L +Q + L  +   L
Sbjct: 284 SQALREEAQR--------RDSALQQLRTAVKELSVQNQDLIEKNLTL 322



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 28/176 (15%), Positives = 74/176 (42%), Gaps = 4/176 (2%)

Query: 294 ENEPTDRETEIWKELQMTRGALLRSEEELRQSRAE---KDSFLNSLSRIAQGEGTESFQD 350
           E + +  E E+    +  + AL +  EE+++       +D  +N+L +  Q E  ++ + 
Sbjct: 86  EKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREK 145

Query: 351 KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           +   E L+R    +   +   +Q +  K  E   T+ + ++  L   ++  +   C  K+
Sbjct: 146 QQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAI-CREKE 204

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARK 466
           +    L+    +      +L  +++   T+     + +E  ++  D   ++V  ++
Sbjct: 205 IQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQ 260


>AL451139-13|CAI15848.2|  762|Homo sapiens coiled-coil domain
           containing 21 protein.
          Length = 762

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 71/287 (24%), Positives = 119/287 (41%), Gaps = 26/287 (9%)

Query: 161 VARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ 220
           V   R+  L+R+    +A+F    +K + L +    L  + S + V+V+ +RE  + A Q
Sbjct: 379 VCLLRLQELQRENTFLRAQFA---QKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQ 435

Query: 221 VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
                V +Q+ R +     +   +K                      L+ +      L D
Sbjct: 436 KHSEEVKKQEERVKGRDKHINNLKKK----CQKESEQNREKQQRIETLERYLADLPTLED 491

Query: 281 MERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE---EELRQSRAEKDSFLNSL 336
            +++ + L+    K  E  ++ TE+   L+ T+      E   E LRQ  AE  S  +SL
Sbjct: 492 HQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSL 551

Query: 337 S-----RIAQGEGTESFQDKMATELLDREQKIV-KLQQTIDEQRENEKSMEQTMTQYENQ 390
                     GEG E   +       D  QKIV K QQ +D+ R   +S+EQ + Q E  
Sbjct: 552 QDKQSVEETSGEGPEVEMESWQKRY-DSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGT 610

Query: 391 LAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
             ALR E +R        +D +  +L+T + +L +Q + L  +   L
Sbjct: 611 SQALREEAQR--------RDSALQQLRTAVKELSVQNQDLIEKNLTL 649



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 28/176 (15%), Positives = 74/176 (42%), Gaps = 4/176 (2%)

Query: 294 ENEPTDRETEIWKELQMTRGALLRSEEELRQSRAE---KDSFLNSLSRIAQGEGTESFQD 350
           E + +  E E+    +  + AL +  EE+++       +D  +N+L +  Q E  ++ + 
Sbjct: 413 EKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREK 472

Query: 351 KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           +   E L+R    +   +   +Q +  K  E   T+ + ++  L   ++  +   C  K+
Sbjct: 473 QQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAI-CREKE 531

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARK 466
           +    L+    +      +L  +++   T+     + +E  ++  D   ++V  ++
Sbjct: 532 IQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQ 587


>AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open reading
           frame 60 protein.
          Length = 1140

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 92/447 (20%), Positives = 175/447 (39%), Gaps = 36/447 (8%)

Query: 37  RVLSNLEWKTRNTE--FDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKK- 93
           +++ + E K    +  ++ + + L R     AE+L+A      ++ K  +  ++ +++K 
Sbjct: 243 KLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRK-EFQGQEAILRKT 301

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           I +L+ E  ++Q +      K  +      +     N QVL ++L   +    AL     
Sbjct: 302 IGKLKTELQMVQDEAGSLLDKCQKLQTALAIAEN--NVQVLQKQLDDAKEGEMALLSKHK 359

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             ES L  AR R+      L    +   + +      E  +  L  E+S    ++ +L E
Sbjct: 360 EVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEE 419

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA-VAXXXXXXXXXXXXXXXXQLQSFR 272
           +        QS   EQK +   L+ KV E ++++                    QL    
Sbjct: 420 ERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAH 479

Query: 273 DRSIRLVDMERRRCLEYVPC-----KENEPTDRETEIWKE---LQMTRGALLRSEEELRQ 324
            +++  +  +    +E V       K+    D E +  K+   L+  +  L +  E L++
Sbjct: 480 SKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKE 539

Query: 325 SRAEKDSFLNS--------LSRIAQGEGTE-----SFQDKMATELLDREQKIVK--LQQT 369
              +K +  N         + +  QG G+      S QD    E L  E  + K  L++T
Sbjct: 540 VLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQ--ERLQNELDLTKDSLKET 597

Query: 370 IDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVE 428
            D     E  +EQ   Q+E  +AA++ E K   +   +  ++ + E L+ E   L    E
Sbjct: 598 KDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLR---E 654

Query: 429 TLSRERTALITAAASRALMLERHERAA 455
            L  +      +A S+ L L+  E+ A
Sbjct: 655 ELRLQHEEDKKSAMSQLLQLKDREKNA 681


>AL355877-3|CAH71541.2|  434|Homo sapiens coiled-coil domain
           containing 21 protein.
          Length = 434

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 71/287 (24%), Positives = 119/287 (41%), Gaps = 26/287 (9%)

Query: 161 VARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ 220
           V   R+  L+R+    +A+F    +K + L +    L  + S + V+V+ +RE  + A Q
Sbjct: 52  VCLLRLQELQRENTFLRAQFA---QKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQ 108

Query: 221 VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
                V +Q+ R +     +   +K                      L+ +      L D
Sbjct: 109 KHSEEVKKQEERVKGRDKHINNLKKK----CQKESEQNREKQQRIETLERYLADLPTLED 164

Query: 281 MERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE---EELRQSRAEKDSFLNSL 336
            +++ + L+    K  E  ++ TE+   L+ T+      E   E LRQ  AE  S  +SL
Sbjct: 165 HQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSL 224

Query: 337 S-----RIAQGEGTESFQDKMATELLDREQKIV-KLQQTIDEQRENEKSMEQTMTQYENQ 390
                     GEG E   +       D  QKIV K QQ +D+ R   +S+EQ + Q E  
Sbjct: 225 QDKQSVEETSGEGPEVEMESWQKRY-DSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGT 283

Query: 391 LAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
             ALR E +R        +D +  +L+T + +L +Q + L  +   L
Sbjct: 284 SQALREEAQR--------RDSALQQLRTAVKELSVQNQDLIEKNLTL 322



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 28/176 (15%), Positives = 74/176 (42%), Gaps = 4/176 (2%)

Query: 294 ENEPTDRETEIWKELQMTRGALLRSEEELRQSRAE---KDSFLNSLSRIAQGEGTESFQD 350
           E + +  E E+    +  + AL +  EE+++       +D  +N+L +  Q E  ++ + 
Sbjct: 86  EKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREK 145

Query: 351 KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           +   E L+R    +   +   +Q +  K  E   T+ + ++  L   ++  +   C  K+
Sbjct: 146 QQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAI-CREKE 204

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARK 466
           +    L+    +      +L  +++   T+     + +E  ++  D   ++V  ++
Sbjct: 205 IQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQ 260


>AL355877-2|CAH71540.2|  762|Homo sapiens coiled-coil domain
           containing 21 protein.
          Length = 762

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 71/287 (24%), Positives = 119/287 (41%), Gaps = 26/287 (9%)

Query: 161 VARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ 220
           V   R+  L+R+    +A+F    +K + L +    L  + S + V+V+ +RE  + A Q
Sbjct: 379 VCLLRLQELQRENTFLRAQFA---QKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQ 435

Query: 221 VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
                V +Q+ R +     +   +K                      L+ +      L D
Sbjct: 436 KHSEEVKKQEERVKGRDKHINNLKKK----CQKESEQNREKQQRIETLERYLADLPTLED 491

Query: 281 MERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE---EELRQSRAEKDSFLNSL 336
            +++ + L+    K  E  ++ TE+   L+ T+      E   E LRQ  AE  S  +SL
Sbjct: 492 HQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSL 551

Query: 337 S-----RIAQGEGTESFQDKMATELLDREQKIV-KLQQTIDEQRENEKSMEQTMTQYENQ 390
                     GEG E   +       D  QKIV K QQ +D+ R   +S+EQ + Q E  
Sbjct: 552 QDKQSVEETSGEGPEVEMESWQKRY-DSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGT 610

Query: 391 LAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
             ALR E +R        +D +  +L+T + +L +Q + L  +   L
Sbjct: 611 SQALREEAQR--------RDSALQQLRTAVKELSVQNQDLIEKNLTL 649



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 28/176 (15%), Positives = 74/176 (42%), Gaps = 4/176 (2%)

Query: 294 ENEPTDRETEIWKELQMTRGALLRSEEELRQSRAE---KDSFLNSLSRIAQGEGTESFQD 350
           E + +  E E+    +  + AL +  EE+++       +D  +N+L +  Q E  ++ + 
Sbjct: 413 EKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREK 472

Query: 351 KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           +   E L+R    +   +   +Q +  K  E   T+ + ++  L   ++  +   C  K+
Sbjct: 473 QQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAI-CREKE 531

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARK 466
           +    L+    +      +L  +++   T+     + +E  ++  D   ++V  ++
Sbjct: 532 IQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQ 587


>AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open reading
           frame 60 protein.
          Length = 1140

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 92/447 (20%), Positives = 175/447 (39%), Gaps = 36/447 (8%)

Query: 37  RVLSNLEWKTRNTE--FDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKK- 93
           +++ + E K    +  ++ + + L R     AE+L+A      ++ K  +  ++ +++K 
Sbjct: 243 KLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRK-EFQGQEAILRKT 301

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           I +L+ E  ++Q +      K  +      +     N QVL ++L   +    AL     
Sbjct: 302 IGKLKTELQMVQDEAGSLLDKCQKLQTALAIAEN--NVQVLQKQLDDAKEGEMALLSKHK 359

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             ES L  AR R+      L    +   + +      E  +  L  E+S    ++ +L E
Sbjct: 360 EVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEE 419

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA-VAXXXXXXXXXXXXXXXXQLQSFR 272
           +        QS   EQK +   L+ KV E ++++                    QL    
Sbjct: 420 ERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAH 479

Query: 273 DRSIRLVDMERRRCLEYVPC-----KENEPTDRETEIWKE---LQMTRGALLRSEEELRQ 324
            +++  +  +    +E V       K+    D E +  K+   L+  +  L +  E L++
Sbjct: 480 SKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKE 539

Query: 325 SRAEKDSFLNS--------LSRIAQGEGTE-----SFQDKMATELLDREQKIVK--LQQT 369
              +K +  N         + +  QG G+      S QD    E L  E  + K  L++T
Sbjct: 540 VLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQ--ERLQNELDLTKDSLKET 597

Query: 370 IDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVE 428
            D     E  +EQ   Q+E  +AA++ E K   +   +  ++ + E L+ E   L    E
Sbjct: 598 KDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLR---E 654

Query: 429 TLSRERTALITAAASRALMLERHERAA 455
            L  +      +A S+ L L+  E+ A
Sbjct: 655 ELRLQHEEDKKSAMSQLLQLKDREKNA 681


>AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open reading
           frame 60 protein.
          Length = 1140

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 92/447 (20%), Positives = 175/447 (39%), Gaps = 36/447 (8%)

Query: 37  RVLSNLEWKTRNTE--FDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKK- 93
           +++ + E K    +  ++ + + L R     AE+L+A      ++ K  +  ++ +++K 
Sbjct: 243 KLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRK-EFQGQEAILRKT 301

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           I +L+ E  ++Q +      K  +      +     N QVL ++L   +    AL     
Sbjct: 302 IGKLKTELQMVQDEAGSLLDKCQKLQTALAIAEN--NVQVLQKQLDDAKEGEMALLSKHK 359

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             ES L  AR R+      L    +   + +      E  +  L  E+S    ++ +L E
Sbjct: 360 EVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEE 419

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA-VAXXXXXXXXXXXXXXXXQLQSFR 272
           +        QS   EQK +   L+ KV E ++++                    QL    
Sbjct: 420 ERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAH 479

Query: 273 DRSIRLVDMERRRCLEYVPC-----KENEPTDRETEIWKE---LQMTRGALLRSEEELRQ 324
            +++  +  +    +E V       K+    D E +  K+   L+  +  L +  E L++
Sbjct: 480 SKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKE 539

Query: 325 SRAEKDSFLNS--------LSRIAQGEGTE-----SFQDKMATELLDREQKIVK--LQQT 369
              +K +  N         + +  QG G+      S QD    E L  E  + K  L++T
Sbjct: 540 VLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQ--ERLQNELDLTKDSLKET 597

Query: 370 IDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVE 428
            D     E  +EQ   Q+E  +AA++ E K   +   +  ++ + E L+ E   L    E
Sbjct: 598 KDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLR---E 654

Query: 429 TLSRERTALITAAASRALMLERHERAA 455
            L  +      +A S+ L L+  E+ A
Sbjct: 655 ELRLQHEEDKKSAMSQLLQLKDREKNA 681


>AK091682-1|BAC03719.1|  936|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34363 fis, clone FEBRA2015042. ).
          Length = 936

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 92/447 (20%), Positives = 175/447 (39%), Gaps = 36/447 (8%)

Query: 37  RVLSNLEWKTRNTE--FDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKK- 93
           +++ + E K    +  ++ + + L R     AE+L+A      ++ K  +  ++ +++K 
Sbjct: 123 KLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRK-EFQGQEAILRKT 181

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           I +L+ E  ++Q +      K  +      +     N QVL ++L   +    AL     
Sbjct: 182 IGKLKTELQMVQDEAGSLLDKCQKLQTALAIAEN--NVQVLQKQLDDAKEGEMALLSKHK 239

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             ES L  AR R+      L    +   + +      E  +  L  E+S    ++ +L E
Sbjct: 240 EVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEE 299

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA-VAXXXXXXXXXXXXXXXXQLQSFR 272
           +        QS   EQK +   L+ KV E ++++                    QL    
Sbjct: 300 ERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAH 359

Query: 273 DRSIRLVDMERRRCLEYVPC-----KENEPTDRETEIWKE---LQMTRGALLRSEEELRQ 324
            +++  +  +    +E V       K+    D E +  K+   L+  +  L +  E L++
Sbjct: 360 SKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKE 419

Query: 325 SRAEKDSFLNS--------LSRIAQGEGTE-----SFQDKMATELLDREQKIVK--LQQT 369
              +K +  N         + +  QG G+      S QD    E L  E  + K  L++T
Sbjct: 420 VLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQ--ERLQNELDLTKDSLKET 477

Query: 370 IDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVE 428
            D     E  +EQ   Q+E  +AA++ E K   +   +  ++ + E L+ E   L    E
Sbjct: 478 KDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLR---E 534

Query: 429 TLSRERTALITAAASRALMLERHERAA 455
            L  +      +A S+ L L+  E+ A
Sbjct: 535 ELRLQHEEDKKSAMSQLLQLKDREKNA 561


>AK024038-1|BAB14794.1|  762|Homo sapiens protein ( Homo sapiens
           cDNA FLJ13976 fis, clone Y79AA1001594, weakly similar to
           HYALURONAN-MEDIATED MOTILITY RECEPTOR. ).
          Length = 762

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 71/287 (24%), Positives = 119/287 (41%), Gaps = 26/287 (9%)

Query: 161 VARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ 220
           V   R+  L+R+    +A+F    +K + L +    L  + S + V+V+ +RE  + A Q
Sbjct: 380 VCLLRLQELQRENTFLRAQFA---QKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQ 436

Query: 221 VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVD 280
                V +Q+ R +     +   +K                      L+ +      L D
Sbjct: 437 KHSEEVKKQEERVKGRDKHINNLKKK----CQKESEQNREKQQRIETLERYLADLPTLED 492

Query: 281 MERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE---EELRQSRAEKDSFLNSL 336
            +++ + L+    K  E  ++ TE+   L+ T+      E   E LRQ  AE  S  +SL
Sbjct: 493 HQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSL 552

Query: 337 S-----RIAQGEGTESFQDKMATELLDREQKIV-KLQQTIDEQRENEKSMEQTMTQYENQ 390
                     GEG E   +       D  QKIV K QQ +D+ R   +S+EQ + Q E  
Sbjct: 553 QDKQSVEETSGEGPEVEMESWQKRY-DSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGT 611

Query: 391 LAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
             ALR E +R        +D +  +L+T + +L +Q + L  +   L
Sbjct: 612 SQALREEAQR--------RDSALQQLRTAVKELSVQNQDLIEKNLTL 650



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 28/176 (15%), Positives = 74/176 (42%), Gaps = 4/176 (2%)

Query: 294 ENEPTDRETEIWKELQMTRGALLRSEEELRQSRAE---KDSFLNSLSRIAQGEGTESFQD 350
           E + +  E E+    +  + AL +  EE+++       +D  +N+L +  Q E  ++ + 
Sbjct: 414 EKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREK 473

Query: 351 KMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKD 410
           +   E L+R    +   +   +Q +  K  E   T+ + ++  L   ++  +   C  K+
Sbjct: 474 QQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAI-CREKE 532

Query: 411 VSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARK 466
           +    L+    +      +L  +++   T+     + +E  ++  D   ++V  ++
Sbjct: 533 IQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQ 588


>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
            protein.
          Length = 1935

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 67/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 1167 REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 1225

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
              L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +R+   
Sbjct: 1226 LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQRAKLQ 1281

Query: 206  VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 1340

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                 Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 1341 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
            EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 1401 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 1458

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
              +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 1515



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 70/353 (19%), Positives = 141/353 (39%), Gaps = 36/353 (10%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 991  KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 1049

Query: 192  QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
            +   +L  +       + +L    +  ++             +R+ +++A    LQ K+ 
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
            E + ++                   +L+S   R +  +            C+      RE
Sbjct: 1110 ELQ-ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKRE 1168

Query: 302  TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
             E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 1228

Query: 354  TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
             ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 1229 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 1288

Query: 402  RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
            R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 1289 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 1339



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 69/373 (18%), Positives = 153/373 (41%), Gaps = 28/373 (7%)

Query: 66   AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
            AE  K   +   E  ++      +  ++ E  +K  S+LQ K D   + + E+      +
Sbjct: 843  AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902

Query: 126  SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                  Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    K+
Sbjct: 903  ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KR 952

Query: 186  KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
               DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 953  DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 1012

Query: 245  KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEI 304
            +   V                 +    +++ +R+ D+ER +             + + ++
Sbjct: 1013 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM-DLERAK----------RKLEGDLKL 1061

Query: 305  WKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIV 364
             +E  M    L   +++L +   +KD  LN+L+  A+ E  ++   ++  +L + + +I 
Sbjct: 1062 TQESIMD---LENDKQQLDERLKKKDFELNALN--ARIEDEQALGSQLQKKLKELQARIE 1116

Query: 365  KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN-YDCYSKDVSYPELQTEILDL 423
            +L++ ++ +R     +E+  +    +L  +   ++       C  +     E + + +  
Sbjct: 1117 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRR 1176

Query: 424  HLQVETLSRERTA 436
             L+  TL  E TA
Sbjct: 1177 DLEEATLQHEATA 1189



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1609 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1668

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
            + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++
Sbjct: 1669 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 71/330 (21%), Positives = 130/330 (39%), Gaps = 38/330 (11%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKEN----EEPPCHPVQSGSYNYQVLNEELSKERAA 144
            T + K++   +E+  L+H   ET K+EN    EE      Q GS    +   EL K R  
Sbjct: 1479 TELFKLKNAYEES--LEHL--ETFKRENKNLQEEISDLTEQLGSSGKTI--HELEKVRKQ 1532

Query: 145  REA----LKEVVASAESMLRVARARIATLERQLKDTKAEFEIA-KKKHKDLEQLV-NRLA 198
             EA    L+  +  AE+ L     +I   + +    KAE E    +K +++EQ   N L 
Sbjct: 1533 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 1592

Query: 199  IERSHATVKVKELREQAET--AEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
            +  S  T    E R + E    ++  +  ++E + +        AE +K           
Sbjct: 1593 VVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSL 1649

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       +++  D    +  +ERR  L     +E      +TE  +  ++    L+
Sbjct: 1650 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELI 1707

Query: 317  RSEEELRQSRAEKDSFLNSLSRI------AQGEGTESFQD---------KMATELLDREQ 361
             + E ++   ++  S +N   ++       Q E  E+ Q+         K  T+     +
Sbjct: 1708 ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE 1767

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ K Q T       +K+MEQT+   +++L
Sbjct: 1768 ELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1797



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1793

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1794 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1843

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1844 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1891

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1892 NLSKFRKVQHELDEAEERADIAESQVNK 1919


>AF273047-1|AAG34907.1|  623|Homo sapiens CTCL tumor antigen se20-7
           protein.
          Length = 623

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 68/297 (22%), Positives = 129/297 (43%), Gaps = 23/297 (7%)

Query: 157 SMLRVARARIATLERQ----LKDTKAEF-EIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
           + LR A+  I  LE+     + +TK +  E  + K +++ QL +R+       T + +EL
Sbjct: 9   TQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRI----KQMTTQGEEL 64

Query: 212 REQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSF 271
           REQ E +E+ A   +  +KA +   + + A + K KA                   LQ  
Sbjct: 65  REQKEKSERAAFEEL--EKALSTAQKTEEARR-KLKAEMDEQIKTIEKTSEEERISLQQE 121

Query: 272 RDR-SIRLVDMERRRCLEYVP----CKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
             R    +VD+ ++   E +       E E   +E E+ K+LQ TR    + + ++   +
Sbjct: 122 LSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQ-TREREFQEQMKVALEK 180

Query: 327 AEKDSFLNSLSRIAQGE-GTESFQDKMATELLDREQKIVKLQQTIDEQR----ENEKSME 381
           ++ +    S  +  Q     E  + +    L + E K+  LQQ  +  R    E E S+E
Sbjct: 181 SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLE 240

Query: 382 QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALI 438
           +++ + +NQ   L + ++  +N       V   + +TE+  L  Q + L  E+  ++
Sbjct: 241 KSLQENKNQSKDLAVHLEAEKNKHNMEITVMVEKHKTELESLKHQQDALWTEKLQVL 297



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 55/323 (17%), Positives = 138/323 (42%), Gaps = 18/323 (5%)

Query: 106 HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARAR 165
           H+  E  ++E  +      Q  +   ++  ++   ERAA E L++ +++A+      R  
Sbjct: 37  HETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKL 96

Query: 166 IATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSR 225
            A ++ Q+K  +   + ++++   L+Q ++R  +++    V  K   EQ    +++ +  
Sbjct: 97  KAEMDEQIKTIE---KTSEEERISLQQELSR--VKQEVVDVMKKSSEEQIAKLQKLHEKE 151

Query: 226 VS-EQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERR 284
           ++ +++  T+ LQ +  E ++   VA                Q +S    ++  ++++++
Sbjct: 152 LARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESL---ALEELELQKK 208

Query: 285 RCLEYVPCKENE-PTDRETEIWKELQMTRGALLRSEEELRQSR-------AEKDSFLNSL 336
             L     K  +   + ET   + L++        +E   QS+       AEK+     +
Sbjct: 209 AILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNMEI 268

Query: 337 SRIAQGEGTESFQDKMATELLDREQ-KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALR 395
           + + +   TE    K   + L  E+ +++K Q   + ++  EK  ++  T  +++    +
Sbjct: 269 TVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQ 328

Query: 396 LEVKRLRNYDCYSKDVSYPELQT 418
             ++ +        DV   EL++
Sbjct: 329 AHIEEMNEKTLEKLDVKQTELES 351



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 85/425 (20%), Positives = 168/425 (39%), Gaps = 38/425 (8%)

Query: 3   KNLIAQ--QNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR 60
           KNLI Q  Q+  +      R M     +  E + ++R     +  T+  E     E+  R
Sbjct: 15  KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIK-QMTTQGEELREQKEKSER 73

Query: 61  MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIER--------LQKENSILQHKVDETS 112
                 E   +    + E  +    + D  IK IE+        LQ+E S ++ +V +  
Sbjct: 74  AAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM 133

Query: 113 KKENEEP-----PCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES-MLRVARARI 166
           KK +EE        H  +      ++  +  ++ER  +E +K  +  ++S  L++++   
Sbjct: 134 KKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQ--- 190

Query: 167 ATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRV 226
              E++ +++ A  E+  +K   L +  N+L   +  A      + E   + E+  Q   
Sbjct: 191 ---EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK 247

Query: 227 SEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRC 286
           ++ K     L+A   E+ K                     Q  +     ++++  + +  
Sbjct: 248 NQSKDLAVHLEA---EKNKHNMEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTE 304

Query: 287 LEYV--PCKENEPT---DRE----TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLS 337
           +E +   C++ + T   D+E      I +  + T   L   + EL    +E    L +  
Sbjct: 305 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARH 364

Query: 338 RIAQGEGTESFQ-DKMATELLDR--EQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAAL 394
           ++ +       Q DKM  EL  +  EQK    QQ     +E+E S+++T    ++Q+  L
Sbjct: 365 KLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQL 424

Query: 395 RLEVK 399
            L +K
Sbjct: 425 ELLLK 429


>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
            cardiac muscle, beta variant protein.
          Length = 1574

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 67/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 806  REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 864

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
              L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +R+   
Sbjct: 865  LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQRAKLQ 920

Query: 206  VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
             +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 921  TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 979

Query: 262  XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                 Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 980  DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1039

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
            EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 1040 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 1097

Query: 376  NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
              +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 1098 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 1154



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 135  NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 1248 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 1307

Query: 192  QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
            + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++
Sbjct: 1308 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1358



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 68/373 (18%), Positives = 154/373 (41%), Gaps = 28/373 (7%)

Query: 66  AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
           AE  K   +   E  ++      +  ++ E  +K  S+LQ K D   + + E+      +
Sbjct: 482 AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 541

Query: 126 SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                 Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    K+
Sbjct: 542 ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KR 591

Query: 186 KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
              DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 592 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 651

Query: 245 KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEI 304
           +   V                 +    +++ +R+ D+ER +             + + ++
Sbjct: 652 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM-DLERAK----------RKLEGDLKL 700

Query: 305 WKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIV 364
            +E  M    L   +++L +   +KD  LN+L+  A+ E  ++   ++  +L + + +I 
Sbjct: 701 TQESIMD---LENDKQQLDERLKKKDFELNALN--ARIEDEQALGSQLQKKLKELQARIE 755

Query: 365 KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP-ELQTEILDL 423
           +L++ ++ +R     +E+  +    +L  +   ++          +++   E + + +  
Sbjct: 756 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 815

Query: 424 HLQVETLSRERTA 436
            L+  TL  E TA
Sbjct: 816 DLEEATLQHEATA 828



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 69/340 (20%), Positives = 137/340 (40%), Gaps = 24/340 (7%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L   L +E+  R  L+      E  L++ +  I  LE    D +   E  KKK  +L  L
Sbjct: 673 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN---DKQQLDERLKKKDFELNAL 729

Query: 194 VNRLAIER---SHATVKVKELREQAETAEQVAQ----SRVSEQKARTEFLQAKVAEQEKS 246
             R+  E+   S    K+KEL+ + E  E+  +    +R   +K R++ L  ++ E  + 
Sbjct: 730 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD-LSRELEEISER 788

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
              A                + Q  R R +    ++       +  K     D   E+ +
Sbjct: 789 LEEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGE 844

Query: 307 ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR-EQKIVK 365
           ++   +    + E+E  + + E D   +++ +I + +      +KM   L D+  +   K
Sbjct: 845 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKMCRTLEDQMNEHRSK 901

Query: 366 LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
            ++T  ++  N+ + ++   Q EN   + +L+ K           ++Y + Q E L   L
Sbjct: 902 AEET--QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQL 958

Query: 426 QVETLSRERT--ALITAAASRALMLERHERAADLFARMVR 463
           + E  ++     AL +A     L+ E++E   +  A + R
Sbjct: 959 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 998



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 69/353 (19%), Positives = 140/353 (39%), Gaps = 36/353 (10%)

Query: 132 QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
           ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 630 KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 688

Query: 192 QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
           +   +L  +       + +L    +  ++             +R+ +++A    LQ K+ 
Sbjct: 689 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 748

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
           E + ++                   +L+S   R +  +             +      RE
Sbjct: 749 ELQ-ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 807

Query: 302 TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
            E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 808 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 867

Query: 354 TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
            ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 868 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELS 927

Query: 402 RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
           R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 928 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 978



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 71/330 (21%), Positives = 130/330 (39%), Gaps = 38/330 (11%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKEN----EEPPCHPVQSGSYNYQVLNEELSKERAA 144
            T + K++   +E+  L+H   ET K+EN    EE      Q GS    +   EL K R  
Sbjct: 1118 TELFKLKNAYEES--LEHL--ETFKRENKNLQEEISDLTEQLGSSGKTI--HELEKVRKQ 1171

Query: 145  REA----LKEVVASAESMLRVARARIATLERQLKDTKAEFEIA-KKKHKDLEQLV-NRLA 198
             EA    L+  +  AE+ L     +I   + +    KAE E    +K +++EQ   N L 
Sbjct: 1172 LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 1231

Query: 199  IERSHATVKVKELREQAET--AEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
            +  S  T    E R + E    ++  +  ++E + +        AE +K           
Sbjct: 1232 VVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSL 1288

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       +++  D    +  +ERR  L     +E      +TE  +  ++    L+
Sbjct: 1289 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELI 1346

Query: 317  RSEEELRQSRAEKDSFLNSLSRI------AQGEGTESFQD---------KMATELLDREQ 361
             + E ++   ++  S +N   ++       Q E  E+ Q+         K  T+     +
Sbjct: 1347 ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE 1406

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ K Q T       +K+MEQT+   +++L
Sbjct: 1407 ELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1436



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 1374 SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1432

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1433 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1482

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1483 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1530

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1531 NLSKFRKVQHELDEAEERADIAESQVNK 1558


>AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and
            Golgi-localized PKN-associated protein (CG-NAP) protein.
          Length = 3899

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 81/385 (21%), Positives = 151/385 (39%), Gaps = 30/385 (7%)

Query: 97   LQKENSILQHKVDETSKK--ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
            LQK+   L+  V+E   +  E E+     +       Q L ++L K    R+ L E    
Sbjct: 2019 LQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK---MRKFLDEQAID 2075

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E    V +  I  LE+QLK       I++ + +++EQL N L  E++    ++   +EQ
Sbjct: 2076 REHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLK-EKTDKCSELLLSKEQ 2134

Query: 215  AETAEQVAQSRVSEQKART-EFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
             +   Q     + + + R  E +QA + E  K                          ++
Sbjct: 2135 LQRDIQERNEEIEKLEFRVRELVQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKE 2194

Query: 274  RSIRLVDMERRRCLEYVPCKENE--PTDRETEIWKELQMTRGALLRSEEELRQSRAEK-- 329
            + I  ++ +  +  E +  K  E      + EI K+   TR   L  E +L +   EK  
Sbjct: 2195 KEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLG 2254

Query: 330  ------DSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENE--KSME 381
                  D+       +  G+  +  Q+K   E+    +++ KLQQ +    +N+  +   
Sbjct: 2255 LAIKESDAMSTQDQHVLFGKFAQIIQEK-EVEIDQLNEQVTKLQQQLKITTDNKVIEEKN 2313

Query: 382  QTMTQYENQLAALRLE---VKRLRNYDCYSKDVSYPELQTEILDL----HLQVETLSRER 434
            + +   E Q+  L  +   VKR R  +    +    +LQ E+ ++     +   +LS E 
Sbjct: 2314 ELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEA 2373

Query: 435  TAL---ITAAASRALMLERHERAAD 456
             +L   +    +  L LE+    A+
Sbjct: 2374 DSLKHQLDVVIAEKLALEQQVETAN 2398



 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 92/444 (20%), Positives = 186/444 (41%), Gaps = 42/444 (9%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIK----KIERLQKENSILQ 105
           E ++     H+ ++ + E+LKA+I  + E  K   L  +  +     K+E L+KE + + 
Sbjct: 553 EQESKLNEAHKSLSTV-EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVL 611

Query: 106 HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE-RAAREALKEVVA-----SAESML 159
            ++ E+ + E E      + S       L E+L  E R + E LK+ +        + + 
Sbjct: 612 DRMAESQEAELERLSTQLLFSHEEELSKLKEDLEIEHRISIEKLKDNLGIHYKQQIDGLQ 671

Query: 160 RVARARIATLERQLKD--TKAEFEIAK-KKHKDLEQ-LVNRLAIERS---HATVKVKELR 212
                +I T++ +  +  TK    I +  K KDL+Q LVN  + E +   +   K  E+ 
Sbjct: 672 NEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEIL 731

Query: 213 EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            Q E  +   +  V E + +TE L+ ++ E+E                       L+   
Sbjct: 732 RQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 791

Query: 273 DRSIRLVDMERRRCLEYVPCKENEPTDRETEIW-KELQMTRGALLRSEEELRQSRAEKDS 331
                +   ER   L+ +  K  +       +W KE+++    L+   E+L+Q   +   
Sbjct: 792 KIHTPVSQEERLIFLDSIKSKSKD------SVWEKEIEI----LIEENEDLKQQCIQ--- 838

Query: 332 FLNSLSRIAQGEGTESFQDK-MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
            LN    I +   T SF +K       + +++   L +  D+  +++   E    +Y+++
Sbjct: 839 -LN--EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE---LEYKSK 892

Query: 391 LAAL--RLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALI-TAAASRALM 447
           L AL   L ++R+       K   + E +T + +     E + ++ T L+     ++   
Sbjct: 893 LKALNEELNLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMENLEVTKREK 952

Query: 448 LERHERAADLFARMVRARKDLAAL 471
           LE  +R +DL  ++ +   +++ L
Sbjct: 953 LELSQRLSDLSEQLKQKHGEISFL 976



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 66/350 (18%), Positives = 143/350 (40%), Gaps = 22/350 (6%)

Query: 92  KKIERLQKENSILQHKV---DETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
           KK E    + S LQ K+   +    K+ E      +Q      + LN ++ +E      L
Sbjct: 289 KKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLEL 348

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL--AIE----RS 202
           K+ + +A+ +L   + +I    +++K+ K E   +K+K +   + + +L   +E    R+
Sbjct: 349 KDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRN 408

Query: 203 HATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
           H   + +   +  +  EQ  Q ++ + +A  + +  +   Q K + +             
Sbjct: 409 HKDSQFE--TDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEIKTR 466

Query: 263 XXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN---EPTDRETEIWKE----LQMTRGAL 315
                  + R  S   V+ ++ + +     + N   + T+ + E  KE    +   + AL
Sbjct: 467 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 526

Query: 316 LRSEEELRQSRA-EKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            R  E+L +  +  +     +   IA+ E   +   K  + + D + +IV   ++   ++
Sbjct: 527 QRQLEDLVEELSFSRGQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASES---RK 583

Query: 375 ENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
           E E   E  +T Y+ +L  L  E   + +    S++     L T++L  H
Sbjct: 584 ELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLSTQLLFSH 633



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 3/133 (2%)

Query: 308  LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
            L  ++G  + SE    +S +  DSF   +  + +    +  Q    TE    + +   +Q
Sbjct: 2907 LTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNDGMQVLSLTESPYSDGEDHSIQ 2966

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
            Q  +   E  K+   T++  ++ +  ++L+ +    YD      S+ + + E+L L LQ 
Sbjct: 2967 QVSESWLEERKAYINTISSLKDLITKMQLQ-REAEVYDSSQSHESFSDWRGELL-LALQ- 3023

Query: 428  ETLSRERTALITA 440
            +    ER+ L+ A
Sbjct: 3024 QVFLEERSVLLAA 3036


>X03740-1|CAA27380.1|  876|Homo sapiens protein ( Human skeletal
           mRNA for myosin heavy chain light meromyosin region. ).
          Length = 876

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 65/357 (18%), Positives = 144/357 (40%), Gaps = 18/357 (5%)

Query: 87  RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
           R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  E
Sbjct: 108 REAEFQKMRR-DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKS--E 164

Query: 147 ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
              E+   A +M  V++A+   LE+  +  + +    K K ++ ++L+N L  +R+    
Sbjct: 165 MKMEIDDLASNMETVSKAK-GNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQ 223

Query: 207 KVKELREQAETAEQVAQSRVSEQKART---EFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
              E   Q +  + +       ++A T   E L+ ++ E+ K+K+               
Sbjct: 224 NQVEYSRQLDEKDTLETQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDL 283

Query: 264 XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEE 321
              Q +  ++    L     +   E    +    TD  + TE  +E +      L+  EE
Sbjct: 284 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 343

Query: 322 LRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRENE 377
             ++   K + L    +  Q E  +   D      A   LD++Q      + + E ++  
Sbjct: 344 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQ--TNFDKILAEWKQKC 401

Query: 378 KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
           +     +  ++ +  +L  E+ +++N   Y + +   E L+ E  +L  ++  L+ +
Sbjct: 402 EETHAVLESFQKESRSLSTELFKIKN--AYEESLDQLETLKRENKNLQQEISDLTEQ 456



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 58/285 (20%), Positives = 112/285 (39%), Gaps = 22/285 (7%)

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKAR 232
           LKDT+   + A +  +DL++   +LA+    A +   E+ E   T EQ  +SR   + A 
Sbjct: 591 LKDTQLHLDDALRSQEDLKE---QLAMVERRANLLQAEIEELRATLEQTERSR---KIAE 644

Query: 233 TEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPC 292
            E L A  +E+ +                     Q+Q   +  I+    E R   E    
Sbjct: 645 QELLDA--SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIK----EARNAEEKAKK 698

Query: 293 KENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKM 352
              +      E+ KE Q T   L R ++ L Q+  +    L+   ++A   G +  Q K+
Sbjct: 699 AITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ-KL 756

Query: 353 ATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVS 412
                  E K+ +L+  ++ +++      + + ++E ++  L  + +  R      +D+ 
Sbjct: 757 -------EAKVRELEGEVESEQKRNVEAVKGLHKHERKVKELTYQTEEDRKNILRLQDL- 808

Query: 413 YPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADL 457
             +LQ ++     Q E    +    ++        LE  E  AD+
Sbjct: 809 VDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADI 853



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 57/252 (22%), Positives = 110/252 (43%), Gaps = 18/252 (7%)

Query: 2   RKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR- 60
           R NL+  Q  + E  A L   E    +A + L +      L   T+NT   N  ++L   
Sbjct: 618 RANLL--QAEIEELRATLEQTERSRKIAEQELLDASERVQL-LHTQNTSLINTKKKLETD 674

Query: 61  --MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEE 118
              + G  E++  +   + E AK    D   M +++++ Q  ++ L+ ++ +  ++  ++
Sbjct: 675 ISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE-RMKKNLEQTVKD 733

Query: 119 PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKA 178
                 ++     +   +++ K  A    L+  V S +     A   +   ER++K+   
Sbjct: 734 LQHRLDEAEQLALKGGKKQIQKLEAKVRELEGEVESEQKRNVEAVKGLHKHERKVKELTY 793

Query: 179 EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQA 238
           + E  +K    L+ LV++L         KVK  + QAE AE+  QS V+  K R   +Q 
Sbjct: 794 QTEEDRKNILRLQDLVDKLQ-------AKVKSYKRQAEEAEE--QSNVNLSKFRR--IQH 842

Query: 239 KVAEQEKSKAVA 250
           ++ E E+   +A
Sbjct: 843 ELEEAEERADIA 854


>BX538186-1|CAD98058.1|  971|Homo sapiens hypothetical protein
           protein.
          Length = 971

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 92/447 (20%), Positives = 174/447 (38%), Gaps = 36/447 (8%)

Query: 37  RVLSNLEWKTRNTE--FDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKK- 93
           +++ + E K    +  ++ + + L R     AE+L+A      ++ K  +  ++ +++K 
Sbjct: 123 KLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRK-EFQGQEAILRKT 181

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           I +L+ E  ++Q +      K  +      +     N QVL ++L   +    AL     
Sbjct: 182 IGKLKTELQMVQDEAGSLLDKCQKLQTALAIAEN--NVQVLQKQLDDAKEGEMALLSKHK 239

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             ES L  AR R+      L    +   + +      E  +  L  E+S    ++ +L E
Sbjct: 240 EVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEE 299

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA-VAXXXXXXXXXXXXXXXXQLQSFR 272
           +        QS   EQK +   L+ KV E ++++                    QL    
Sbjct: 300 ERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAH 359

Query: 273 DRSIRLVDMERRRCLEYVPC-----KENEPTDRETEIWKE---LQMTRGALLRSEEELRQ 324
            +++  +  +    +E V       K+    D E +  K+   L+  +  L +  E L++
Sbjct: 360 SKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKE 419

Query: 325 SRAEKDSFLNS--------LSRIAQGEGTE-----SFQDKMATELLDREQKIVK--LQQT 369
              +K    N         + +  QG G+      S QD    E L  E  + K  L++T
Sbjct: 420 VLEDKLDTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQ--ERLQNELDLTKDSLKET 477

Query: 370 IDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVE 428
            D     E  +EQ   Q+E  +AA++ E K   +   +  ++ + E L+ E   L    E
Sbjct: 478 KDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLR---E 534

Query: 429 TLSRERTALITAAASRALMLERHERAA 455
            L  +      +A S+ L L+  E+ A
Sbjct: 535 ELRLQHEEDKKSAMSQLLQLKDREKNA 561


>BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.
          Length = 1726

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 69/358 (19%), Positives = 148/358 (41%), Gaps = 23/358 (6%)

Query: 109  DETSKKENEEPPCHPVQSGSYNYQVLNEELS---KERAAREALKEVVASAESMLRVARAR 165
            D T   E     C    S   N+ +L E+L    K+  +   +++   S E +L + +  
Sbjct: 702  DLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNH 761

Query: 166  IATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVA 222
               L  ++K  + +  + +++  + +++ ++L  ++     ++  LR    Q E   + A
Sbjct: 762  CELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA 821

Query: 223  QS---RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
             +   ++ EQ  R E    K  E ++   ++                Q+   R+ + R +
Sbjct: 822  DTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 881

Query: 280  DMERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSR 338
              E+  R L+      +    +E E+ ++   +  +    EE+     + K+S L     
Sbjct: 882  SREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEK---DLSHKNSMLQEEIA 938

Query: 339  IAQGE-GTESFQDKMATELLDREQKIVK-----LQQTIDEQRENEKSMEQTMTQYENQLA 392
            + + E  T   Q++   +    + KIVK     LQ+TI   ++NE+++ QT++QY  +L+
Sbjct: 939  MLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTI---KQNEETLTQTISQYNGRLS 995

Query: 393  ALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLER 450
             L  E   + N    ++  S   L+ E+   H ++     +R    T+     L  +R
Sbjct: 996  VLTAE-NAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQR 1052



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 79/381 (20%), Positives = 166/381 (43%), Gaps = 34/381 (8%)

Query: 87   RDTMIKKIERLQKENSILQHKVDET-SKKENEEPPCHPVQSGSYNY-QVLNEELSKERAA 144
            ++++ +++ +LQ EN +L+ ++D+  +K +N+E     +Q   +   Q L  E  K+   
Sbjct: 1145 QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL 1204

Query: 145  -REALKEVVASAESML-RVARARIATLERQLKDTKAEFEIAK--KKHKDLE---QLVNRL 197
              E  KE+++    +  R  +      ER++   + + E+A   KK    E   ++ +R 
Sbjct: 1205 LEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRY 1264

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXX 257
             I     T  +K+   Q     Q AQ R +E     E +Q    + EK  A         
Sbjct: 1265 RINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQ 1324

Query: 258  XXXXXXXXXQL------QSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIWKEL-Q 309
                      L      +  +++  +L+++++   C      K+N   +RE   +K L +
Sbjct: 1325 MDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLK 1384

Query: 310  MTRGALLRSEE-------ELRQSRAEKDSFLNSLSR-----IAQGE--GTESFQDKMATE 355
            MTR  L   E        +L+ S+ E D  +N L        A+ E  G++        +
Sbjct: 1385 MTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 1444

Query: 356  LLDREQKIVK-LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP 414
            +L  E   +K +Q+  ++ ++N+K +EQ +    + +    +E+ +++ Y    ++ +  
Sbjct: 1445 ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1504

Query: 415  ELQTEI--LDLHLQVETLSRE 433
            E+  ++  ++L LQ +  S+E
Sbjct: 1505 EIAEKLKEVNLFLQAQAASQE 1525


>BC129821-1|AAI29822.1|  315|Homo sapiens FLJ36144 protein protein.
          Length = 315

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 53/241 (21%), Positives = 109/241 (45%), Gaps = 21/241 (8%)

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
           +E +   E  +R    ++   E +L++ + +    ++K    E+   RL  +      + 
Sbjct: 5   EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEK---RLREQEKELREQE 61

Query: 209 KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL 268
           KELREQ E  EQ  Q +  E+K   +  + K+ EQE+                     Q 
Sbjct: 62  KELREQKELREQEEQMQEQEEKMWEQ--EEKMREQEEK----------MWRQEERLWEQE 109

Query: 269 QSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE-IWKELQMTRGALLRSEEELRQSRA 327
           +  R++  ++ D E R   +    +E E   RE E +W++++  R      E+E +++R 
Sbjct: 110 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE-KKTRD 168

Query: 328 EKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQY 387
           +++  +    RI + E  +  +++  T + ++E+K+ K ++ + EQ E E   ++   Q 
Sbjct: 169 QEEK-MQEEERIRERE--KKMREEEET-MREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 224

Query: 388 E 388
           E
Sbjct: 225 E 225


>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
            skeletal muscle, adult protein.
          Length = 1941

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 65/357 (18%), Positives = 144/357 (40%), Gaps = 18/357 (5%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  E
Sbjct: 1173 REAEFQKMRR-DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKS--E 1229

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
               E+   A ++  V++A+   LE+  +  + +    K K ++ ++L+N L  +R     
Sbjct: 1230 MKMEIDDLASNVETVSKAK-GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQT 1288

Query: 207  KVKELREQAETAEQVAQSRVSEQKART---EFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            +  E   Q +  E +       ++A T   E L+ ++ E+ K+K                
Sbjct: 1289 ESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEE 321
               Q +  ++    L     +   E    +    TD  + TE  +E +      L++ EE
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408

Query: 322  LRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRENE 377
              ++   K + L    +  Q E  +   D      A   LD++Q+     + + E ++  
Sbjct: 1409 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQR--NFDKILAEWKQKC 1466

Query: 378  KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
            +     +   + +  +L  E+ +++N   Y + +   E L+ E  +L  ++  L+ +
Sbjct: 1467 EETHAELEASQKEARSLGTELFKIKN--AYEESLDQLETLKRENKNLQQEISDLTEQ 1521



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 74/358 (20%), Positives = 144/358 (40%), Gaps = 46/358 (12%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++ L ++ A  + +  + +A+I  LE+Q+ D +   E  KK   DLE
Sbjct: 997  KLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIK-LEQQVDDLEGSLEQEKKLRMDLE 1055

Query: 192  QLVNRL--------------AIERSHATVKVKE-------LREQAETAEQVA---QSRVS 227
            +   +L                E+     K+K+       L+ + E  + +    Q ++ 
Sbjct: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIK 1115

Query: 228  EQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCL 287
            E +AR E L+ ++  +  S+A A                +L+     +   ++M ++R  
Sbjct: 1116 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175

Query: 288  EYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES 347
            E+   +     D E E   + + T   L +   +   S AE    +++L R+ Q    E 
Sbjct: 1176 EFQKMRR----DLE-EATLQHEATAATLRKKHAD---SVAELGEQIDNLQRVKQKLEKEK 1227

Query: 348  FQDKMATELLDREQKIV--------KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + KM  + L    + V        K+ +T+++Q    KS E+   +  N L A R  ++
Sbjct: 1228 SEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287

Query: 400  RLR---NYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
                  +     K+    +L         Q+E L R+    I A  A + AL   RH+
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345



 Score = 35.9 bits (79), Expect = 0.32
 Identities = 52/295 (17%), Positives = 126/295 (42%), Gaps = 18/295 (6%)

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +K ++ SAE+        +AT++ + +  K E   ++ K K+LE+ +  L  E++   ++
Sbjct: 842  IKPLLKSAET-----EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQ 896

Query: 208  VKE----LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            V+     L +  E  +Q+ ++++ + +A+ + +  +  ++E+  A               
Sbjct: 897  VQAEAEGLADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 955

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
                +    + ++  V+ E+      V     E    +  I K  +  +      ++ L 
Sbjct: 956  LKKDIDDL-ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1014

Query: 324  QSRAEKDSFLNSL--SRIAQGEGTESFQDKMATE---LLDREQKIVKLQQTIDEQRENEK 378
              +AE+D  +N+L  ++I   +  +  +  +  E    +D E+   KL+  +   +E+  
Sbjct: 1015 DLQAEEDK-VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIM 1073

Query: 379  SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
             +E    Q + +L     E+  L++     +     +LQ +I +L  ++E L  E
Sbjct: 1074 DIENEKQQLDEKLKKKEFEISNLQS-KIEDEQALGIQLQKKIKELQARIEELEEE 1127



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 11/181 (6%)

Query: 207  KVKELREQAETAEQVAQSRVSEQKARTEFL--QAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            K+K L + AET +++A  +   QK + E    +AK  E E+                   
Sbjct: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               L    +R  +L+  + +  LE    +  E  + E EI  EL   +  L   E+E  +
Sbjct: 901  AEGLADAEERCDQLIKTKIQ--LEAKIKEVTERAEDEEEINAELTAKKRKL---EDECSE 955

Query: 325  SRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
             + + D    +L+++  +   TE+    +  E+   ++ I KL +   E++  +++ +QT
Sbjct: 956  LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK---EKKALQEAHQQT 1012

Query: 384  M 384
            +
Sbjct: 1013 L 1013



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 38/236 (16%), Positives = 96/236 (40%), Gaps = 11/236 (4%)

Query: 173  LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQ 229
            LKDT+   + A +  +DL++ +  +    +    +++ELR   EQ E + ++A+  + + 
Sbjct: 1656 LKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1715

Query: 230  KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
              R + L  +      +K                   + ++  +++ + +        E 
Sbjct: 1716 SERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEEL 1775

Query: 290  VPCKENEPTDRETEIWKELQMT-RGALLRSEE-ELRQSRAEKDSFLNSLSRIAQGEGTES 347
               KE + +     + K ++ T +   LR +E E    +  K       +R+ + EG   
Sbjct: 1776 K--KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1833

Query: 348  FQDKMATE----LLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + K   E    L   E+++ +L    +E R+N   ++  + + + ++ + + + +
Sbjct: 1834 SEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1889



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 54/275 (19%), Positives = 109/275 (39%), Gaps = 24/275 (8%)

Query: 67   ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
            E+LK ++      A +   + + +   +E+ ++   I + ++ + S++       H   +
Sbjct: 1671 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQL---LHTQNT 1727

Query: 127  GSYNYQV-LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLK---DTKAEFEI 182
               N +  L  ++S+ +   E + +   +AE   + A    A +  +LK   DT A  E 
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787

Query: 183  AKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE 242
             KK   ++EQ V  L +           L E  + A +  + ++ + +AR   L+ +V  
Sbjct: 1788 MKK---NMEQTVKDLQL----------RLDEAEQLALKGGKKQIQKLEARVRELEGEVES 1834

Query: 243  QEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRET 302
            ++K  A A                Q +  R   +RL D+  +        K  +    E 
Sbjct: 1835 EQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL---QAKVKSYKRQAEEA 1891

Query: 303  EIWKELQMTRGALLRSEEELRQSRAE-KDSFLNSL 336
            E      + +   L+ E E  + RA+  +S +N L
Sbjct: 1892 EEQSNTNLAKFRKLQHELEEAEERADIAESQVNKL 1926


>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
            skeletal muscle, adult protein.
          Length = 1939

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 65/357 (18%), Positives = 145/357 (40%), Gaps = 18/357 (5%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  E
Sbjct: 1171 REAEFQKMRR-DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKS--E 1227

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
               E+   A +M  V++A+   LE+  +  + +    K K ++ ++L+N L  +R+    
Sbjct: 1228 MKMEIDDLASNMETVSKAK-GNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQT 1286

Query: 207  KVKELREQAETAEQVAQSRVSEQKART---EFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            +  E   Q +  + +       ++A T   E L+ ++ E+ K+K+               
Sbjct: 1287 ESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDL 1346

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEE 321
               Q +  ++    L     +   E    +    TD  + TE  +E +      L+  EE
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406

Query: 322  LRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRENE 377
              ++   K + L    +  Q E  +   D      A   LD++Q+     + + E ++  
Sbjct: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQR--NFDKILAEWKQKC 1464

Query: 378  KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
            +     +   + +  +L  E+ +++N   Y + +   E L+ E  +L  ++  L+ +
Sbjct: 1465 EETHAELEASQKESRSLSTELFKIKN--AYEESLDQLETLKRENKNLQQEISDLTEQ 1519



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 69/348 (19%), Positives = 150/348 (43%), Gaps = 35/348 (10%)

Query: 93   KIERLQKENSILQHKVDETS-KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEV 151
            K   L+K    LQ++V++     E     C  +     N+  +  E  ++    E   E+
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQK--CEETHAEL 1471

Query: 152  VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
             AS +   R     +  ++   +++  + E  K+++K+L+Q ++ L  + +    ++ EL
Sbjct: 1472 EASQKES-RSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHEL 1530

Query: 212  REQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSF 271
            +   +  +QV Q + SE +A  E  +A + E E+ K +                 Q++S 
Sbjct: 1531 K---KIKKQVEQEK-SELQAALEEAEASL-EHEEGKIL----------RIQLELNQVKSE 1575

Query: 272  RDRSIRLVDME-RRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD 330
             DR I   D E  +    ++   E+  +  + EI      +R   +R ++++     E +
Sbjct: 1576 VDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEI-----RSRNDAIRLKKKMEGDLNEME 1630

Query: 331  SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
              LN  +R+A  E   ++++  A         +   Q  +D+   +++ +++ +   E +
Sbjct: 1631 IQLNHANRMA-AEALRNYRNTQAI--------LKDTQLHLDDALRSQEDLKEQLAMVERR 1681

Query: 391  LAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALI 438
               L+ E++ LR       + S    + E+LD   +V+ L  + T+LI
Sbjct: 1682 ANLLQAEIEELR-ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLI 1728



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 75/376 (19%), Positives = 146/376 (38%), Gaps = 44/376 (11%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++ L ++ A  + +  + +A+I  LE+Q+ D +   E  KK   DLE
Sbjct: 995  KLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIK-LEQQVDDLEGSLEQEKKIRMDLE 1053

Query: 192  QLVNRLA------------IERSHATVKVKELREQAETA--------EQV----AQSRVS 227
            +   +L             IE     +  K  +++ E +        EQ      Q ++ 
Sbjct: 1054 RAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIK 1113

Query: 228  EQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCL 287
            E +AR E L+ ++  +  S+A A                +L+     +   ++M ++R  
Sbjct: 1114 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1173

Query: 288  EYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES 347
            E+   +     D E E   + + T   L +   +   S AE    +++L R+ Q    E 
Sbjct: 1174 EFQKMRR----DLE-EATLQHEATAATLRKKHAD---SVAELGEQIDNLQRVKQKLEKEK 1225

Query: 348  FQDKMATELLDREQKIV--------KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + KM  + L    + V        K+ + +++Q    K+ E+   +  N L A R  ++
Sbjct: 1226 SEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQ 1285

Query: 400  RLR---NYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAAD 456
                  +     KD    +L         Q+E L R+    I A ++ A  L+      D
Sbjct: 1286 TESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCD 1345

Query: 457  LFARMVRARKDLAALL 472
            L        ++  A L
Sbjct: 1346 LLREQYEEEQEAKAEL 1361



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 52/295 (17%), Positives = 125/295 (42%), Gaps = 18/295 (6%)

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +K ++ SAE+        +A ++ + + TK E    + K K+LE+ +  L  E++   ++
Sbjct: 840  IKPLLKSAET-----EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ 894

Query: 208  VK----ELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            V+     L +  E  +Q+ ++++ + +A+ + +  +  ++E+  A               
Sbjct: 895  VQAEADSLADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 953

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
                +    + ++  V+ E+      V     E    +  I K  +  +      ++ L 
Sbjct: 954  LKKDIDDL-ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012

Query: 324  QSRAEKDSFLNSL--SRIAQGEGTESFQDKMATE---LLDREQKIVKLQQTIDEQRENEK 378
              +AE+D  +N+L  ++I   +  +  +  +  E    +D E+   KL+  +   +E+  
Sbjct: 1013 DLQAEEDK-VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTM 1071

Query: 379  SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
             +E    Q + +L     E+  L++     +     +LQ +I +L  ++E L  E
Sbjct: 1072 DIENDKQQLDEKLKKKEFEMSGLQS-KIEDEQALGMQLQKKIKELQARIEELEEE 1125



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 39/236 (16%), Positives = 94/236 (39%), Gaps = 11/236 (4%)

Query: 173  LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQ 229
            LKDT+   + A +  +DL++ +  +    +    +++ELR   EQ E + ++A+  + + 
Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713

Query: 230  KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
              R + L  +      +K                   + ++  +++ + +        E 
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEEL 1773

Query: 290  VPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ--SRAEKDSFLNSLSRIAQGEGTES 347
               KE + +     + K L+ T   L    +E  Q   +  K       +R+ + EG   
Sbjct: 1774 K--KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1831

Query: 348  FQDKMATE----LLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + K   E    L   E+K+ +L    +E R+N   ++  + + + ++ + + + +
Sbjct: 1832 SEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1887



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 38/181 (20%), Positives = 78/181 (43%), Gaps = 11/181 (6%)

Query: 207  KVKELREQAETAEQVAQSRVSEQKARTEF--LQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            K+K L + AET +++A  +   +K + E    +AK  E E+                   
Sbjct: 839  KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               L    +R  +L+  + +  LE    +  E  + E EI  EL   +  L   E+E  +
Sbjct: 899  ADSLADAEERCDQLIKTKIQ--LEAKIKEVTERAEDEEEINAELTAKKRKL---EDECSE 953

Query: 325  SRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
             + + D    +L+++  +   TE+    +  E+   ++ I KL +   E++  +++ +QT
Sbjct: 954  LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK---EKKALQEAHQQT 1010

Query: 384  M 384
            +
Sbjct: 1011 L 1011



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 57/252 (22%), Positives = 110/252 (43%), Gaps = 18/252 (7%)

Query: 2    RKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR- 60
            R NL+  Q  + E  A L   E    +A + L +      L   T+NT   N  ++L   
Sbjct: 1681 RANLL--QAEIEELRATLEQTERSRKIAEQELLDASERVQL-LHTQNTSLINTKKKLETD 1737

Query: 61   --MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEE 118
               + G  E++  +   + E AK    D   M +++++ Q  ++ L+ ++ +  ++  ++
Sbjct: 1738 ISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE-RMKKNLEQTVKD 1796

Query: 119  PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKA 178
                  ++     +   +++ K  A    L+  V S +     A   +   ER++K+   
Sbjct: 1797 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTY 1856

Query: 179  EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQA 238
            + E  +K    L+ LV++L         KVK  + QAE AE+  QS V+  K R   +Q 
Sbjct: 1857 QTEEDRKNILRLQDLVDKLQ-------AKVKSYKRQAEEAEE--QSNVNLSKFRR--IQH 1905

Query: 239  KVAEQEKSKAVA 250
            ++ E E+   +A
Sbjct: 1906 ELEEAEERADIA 1917


>AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.
          Length = 1710

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 69/358 (19%), Positives = 148/358 (41%), Gaps = 23/358 (6%)

Query: 109  DETSKKENEEPPCHPVQSGSYNYQVLNEELS---KERAAREALKEVVASAESMLRVARAR 165
            D T   E     C    S   N+ +L E+L    K+  +   +++   S E +L + +  
Sbjct: 686  DLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNH 745

Query: 166  IATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVA 222
               L  ++K  + +  + +++  + +++ ++L  ++     ++  LR    Q E   + A
Sbjct: 746  CELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA 805

Query: 223  QS---RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
             +   ++ EQ  R E    K  E ++   ++                Q+   R+ + R +
Sbjct: 806  DTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 865

Query: 280  DMERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSR 338
              E+  R L+      +    +E E+ ++   +  +    EE+     + K+S L     
Sbjct: 866  SREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEK---DLSHKNSMLQEEIA 922

Query: 339  IAQGE-GTESFQDKMATELLDREQKIVK-----LQQTIDEQRENEKSMEQTMTQYENQLA 392
            + + E  T   Q++   +    + KIVK     LQ+TI   ++NE+++ QT++QY  +L+
Sbjct: 923  MLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTI---KQNEETLTQTISQYNGRLS 979

Query: 393  ALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLER 450
             L  E   + N    ++  S   L+ E+   H ++     +R    T+     L  +R
Sbjct: 980  VLTAE-NAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQR 1036



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 79/381 (20%), Positives = 166/381 (43%), Gaps = 34/381 (8%)

Query: 87   RDTMIKKIERLQKENSILQHKVDET-SKKENEEPPCHPVQSGSYNY-QVLNEELSKERAA 144
            ++++ +++ +LQ EN +L+ ++D+  +K +N+E     +Q   +   Q L  E  K+   
Sbjct: 1129 QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL 1188

Query: 145  -REALKEVVASAESML-RVARARIATLERQLKDTKAEFEIAK--KKHKDLE---QLVNRL 197
              E  KE+++    +  R  +      ER++   + + E+A   KK    E   ++ +R 
Sbjct: 1189 LEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRY 1248

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXX 257
             I     T  +K+   Q     Q AQ R +E     E +Q    + EK  A         
Sbjct: 1249 RINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQ 1308

Query: 258  XXXXXXXXXQL------QSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIWKEL-Q 309
                      L      +  +++  +L+++++   C      K+N   +RE   +K L +
Sbjct: 1309 MDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLK 1368

Query: 310  MTRGALLRSEE-------ELRQSRAEKDSFLNSLSR-----IAQGE--GTESFQDKMATE 355
            MTR  L   E        +L+ S+ E D  +N L        A+ E  G++        +
Sbjct: 1369 MTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 1428

Query: 356  LLDREQKIVK-LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP 414
            +L  E   +K +Q+  ++ ++N+K +EQ +    + +    +E+ +++ Y    ++ +  
Sbjct: 1429 ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1488

Query: 415  ELQTEI--LDLHLQVETLSRE 433
            E+  ++  ++L LQ +  S+E
Sbjct: 1489 EIAEKLKEVNLFLQAQAASQE 1509


>AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46736 fis, clone TRACH3020769, weakly  similar
           to Myosin heavy chain, nonmuscle type B. ).
          Length = 1080

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 69/358 (19%), Positives = 148/358 (41%), Gaps = 23/358 (6%)

Query: 109 DETSKKENEEPPCHPVQSGSYNYQVLNEELS---KERAAREALKEVVASAESMLRVARAR 165
           D T   E     C    S   N+ +L E+L    K+  +   +++   S E +L + +  
Sbjct: 243 DLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNH 302

Query: 166 IATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVA 222
              L  ++K  + +  + +++  + +++ ++L  ++     ++  LR    Q E   + A
Sbjct: 303 CELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA 362

Query: 223 QS---RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
            +   ++ EQ  R E    K  E ++   ++                Q+   R+ + R +
Sbjct: 363 DTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 422

Query: 280 DMERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSR 338
             E+  R L+      +    +E E+ ++   +  +    EE+     + K+S L     
Sbjct: 423 SREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEK---DLSHKNSMLQEEIA 479

Query: 339 IAQGE-GTESFQDKMATELLDREQKIVK-----LQQTIDEQRENEKSMEQTMTQYENQLA 392
           + + E  T   Q++   +    + KIVK     LQ+TI   ++NE+++ QT++QY  +L+
Sbjct: 480 MLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTI---KQNEETLTQTISQYNGRLS 536

Query: 393 ALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLER 450
            L  E   + N    ++  S   L+ E+   H ++     +R    T+     L  +R
Sbjct: 537 VLTAE-NAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQR 593



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 79/381 (20%), Positives = 166/381 (43%), Gaps = 34/381 (8%)

Query: 87   RDTMIKKIERLQKENSILQHKVDET-SKKENEEPPCHPVQSGSYNY-QVLNEELSKERAA 144
            ++++ +++ +LQ EN +L+ ++D+  +K +N+E     +Q   +   Q L  E  K+   
Sbjct: 686  QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL 745

Query: 145  -REALKEVVASAESML-RVARARIATLERQLKDTKAEFEIAK--KKHKDLE---QLVNRL 197
              E  KE+++    +  R  +      ER++   + + E+A   KK    E   ++ +R 
Sbjct: 746  LEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRY 805

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXX 257
             I     T  +K+   Q     Q AQ R +E     E +Q    + EK  A         
Sbjct: 806  RINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTIKKQ 865

Query: 258  XXXXXXXXXQL------QSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIWKEL-Q 309
                      L      +  +++  +L+++++   C      K+N   +RE   +K L +
Sbjct: 866  MDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLGQEMKKNVELEREITGFKNLLK 925

Query: 310  MTRGALLRSEE-------ELRQSRAEKDSFLNSLSR-----IAQGE--GTESFQDKMATE 355
            MTR  L   E        +L+ S+ E D  +N L        A+ E  G++        +
Sbjct: 926  MTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 985

Query: 356  LLDREQKIVK-LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP 414
            +L  E   +K +Q+  ++ ++N+K +EQ +    + +    +E+ +++ Y    ++ +  
Sbjct: 986  ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1045

Query: 415  ELQTEI--LDLHLQVETLSRE 433
            E+  ++  ++L LQ +  S+E
Sbjct: 1046 EIAEKLKEVNLFLQAQAASQE 1066


>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
            protein.
          Length = 1939

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 65/357 (18%), Positives = 145/357 (40%), Gaps = 18/357 (5%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  E
Sbjct: 1171 REAEFQKMRR-DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKS--E 1227

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
               E+   A +M  V++A+   LE+  +  + +    K K ++ ++L+N L  +R+    
Sbjct: 1228 MKMEIDDLASNMETVSKAK-GNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQT 1286

Query: 207  KVKELREQAETAEQVAQSRVSEQKART---EFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            +  E   Q +  + +       ++A T   E L+ ++ E+ K+K+               
Sbjct: 1287 ESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDL 1346

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEE 321
               Q +  ++    L     +   E    +    TD  + TE  +E +      L+  EE
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406

Query: 322  LRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRENE 377
              ++   K + L    +  Q E  +   D      A   LD++Q+     + + E ++  
Sbjct: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQR--NFDKILAEWKQKC 1464

Query: 378  KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
            +     +   + +  +L  E+ +++N   Y + +   E L+ E  +L  ++  L+ +
Sbjct: 1465 EETHAELEASQKESRSLSTELFKIKN--AYEESLDQLETLKRENKNLQQEISDLTEQ 1519



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 75/376 (19%), Positives = 146/376 (38%), Gaps = 44/376 (11%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++ L ++ A  + +  + +A+I  LE+Q+ D +   E  KK   DLE
Sbjct: 995  KLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIK-LEQQVDDLEGSLEQEKKIRMDLE 1053

Query: 192  QLVNRLA------------IERSHATVKVKELREQAETA--------EQV----AQSRVS 227
            +   +L             IE     +  K  +++ E +        EQ      Q ++ 
Sbjct: 1054 RAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIK 1113

Query: 228  EQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCL 287
            E +AR E L+ ++  +  S+A A                +L+     +   ++M ++R  
Sbjct: 1114 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1173

Query: 288  EYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES 347
            E+   +     D E E   + + T   L +   +   S AE    +++L R+ Q    E 
Sbjct: 1174 EFQKMRR----DLE-EATLQHEATAATLRKKHAD---SVAELGEQIDNLQRVKQKLEKEK 1225

Query: 348  FQDKMATELLDREQKIV--------KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + KM  + L    + V        K+ + +++Q    K+ E+   +  N L A R  ++
Sbjct: 1226 SEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQ 1285

Query: 400  RLR---NYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAAD 456
                  +     KD    +L         Q+E L R+    I A ++ A  L+      D
Sbjct: 1286 TESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCD 1345

Query: 457  LFARMVRARKDLAALL 472
            L        ++  A L
Sbjct: 1346 LLREQYEEEQEAKAEL 1361



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 52/295 (17%), Positives = 125/295 (42%), Gaps = 18/295 (6%)

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +K ++ SAE+        +A ++ + + TK E    + K K+LE+ +  L  E++   ++
Sbjct: 840  IKPLLKSAET-----EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQ 894

Query: 208  VK----ELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            V+     L +  E  +Q+ ++++ + +A+ + +  +  ++E+  A               
Sbjct: 895  VQAEADSLADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 953

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
                +    + ++  V+ E+      V     E    +  I K  +  +      ++ L 
Sbjct: 954  LKKDIDDL-ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012

Query: 324  QSRAEKDSFLNSL--SRIAQGEGTESFQDKMATE---LLDREQKIVKLQQTIDEQRENEK 378
              +AE+D  +N+L  ++I   +  +  +  +  E    +D E+   KL+  +   +E+  
Sbjct: 1013 DLQAEEDK-VNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAM 1071

Query: 379  SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
             +E    Q + +L     E+  L++     +     +LQ +I +L  ++E L  E
Sbjct: 1072 DIENDKQQLDEKLKKKEFEMSGLQS-KIEDEQALGMQLQKKIKELQARIEELEEE 1125



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 39/236 (16%), Positives = 94/236 (39%), Gaps = 11/236 (4%)

Query: 173  LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQ 229
            LKDT+   + A +  +DL++ +  +    +    +++ELR   EQ E + ++A+  + + 
Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713

Query: 230  KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
              R + L  +      +K                   + ++  +++ + +        E 
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEEL 1773

Query: 290  VPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ--SRAEKDSFLNSLSRIAQGEGTES 347
               KE + +     + K L+ T   L    +E  Q   +  K       +R+ + EG   
Sbjct: 1774 K--KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1831

Query: 348  FQDKMATE----LLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + K   E    L   E+K+ +L    +E R+N   ++  + + + ++ + + + +
Sbjct: 1832 SEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1887



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 38/181 (20%), Positives = 78/181 (43%), Gaps = 11/181 (6%)

Query: 207  KVKELREQAETAEQVAQSRVSEQKARTEF--LQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            K+K L + AET +++A  +   +K + E    +AK  E E+                   
Sbjct: 839  KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               L    +R  +L+  + +  LE    +  E  + E EI  EL   +  L   E+E  +
Sbjct: 899  ADSLADAEERCDQLIKTKIQ--LEAKIKEVTERAEDEEEINAELTAKKRKL---EDECSE 953

Query: 325  SRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
             + + D    +L+++  +   TE+    +  E+   ++ I KL +   E++  +++ +QT
Sbjct: 954  LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK---EKKALQEAHQQT 1010

Query: 384  M 384
            +
Sbjct: 1011 L 1011



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 57/252 (22%), Positives = 110/252 (43%), Gaps = 18/252 (7%)

Query: 2    RKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHR- 60
            R NL+  Q  + E  A L   E    +A + L +      L   T+NT   N  ++L   
Sbjct: 1681 RANLL--QAEIEELRATLEQTERSRKIAEQELLDASERVQL-LHTQNTSLINTKKKLETD 1737

Query: 61   --MVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEE 118
               + G  E++  +   + E AK    D   M +++++ Q  ++ L+ ++ +  ++  ++
Sbjct: 1738 ISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE-RMKKNLEQTVKD 1796

Query: 119  PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKA 178
                  ++     +   +++ K  A    L+  V S +     A   +   ER++K+   
Sbjct: 1797 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTY 1856

Query: 179  EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQA 238
            + E  +K    L+ LV++L         KVK  + QAE AE+  QS V+  K R   +Q 
Sbjct: 1857 QTEEDRKNILRLQDLVDKLQ-------AKVKSYKRQAEEAEE--QSNVNLSKFRR--IQH 1905

Query: 239  KVAEQEKSKAVA 250
            ++ E E+   +A
Sbjct: 1906 ELEEAEERADIA 1917


>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
            protein.
          Length = 1941

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 65/357 (18%), Positives = 144/357 (40%), Gaps = 18/357 (5%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  E
Sbjct: 1173 REAEFQKMRR-DLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKS--E 1229

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
               E+   A ++  V++A+   LE+  +  + +    K K ++ ++L+N L  +R     
Sbjct: 1230 MKMEIDDLASNVETVSKAK-GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQT 1288

Query: 207  KVKELREQAETAEQVAQSRVSEQKART---EFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            +  E   Q +  E +       ++A T   E L+ ++ E+ K+K                
Sbjct: 1289 ESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEEE 321
               Q +  ++    L     +   E    +    TD  + TE  +E +      L++ EE
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408

Query: 322  LRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRENE 377
              ++   K + L    +  Q E  +   D      A   LD++Q+     + + E ++  
Sbjct: 1409 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQR--NFDKILAEWKQKC 1466

Query: 378  KSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
            +     +   + +  +L  E+ +++N   Y + +   E L+ E  +L  ++  L+ +
Sbjct: 1467 EETHAELEASQKEARSLGTELFKIKN--AYEESLDQLETLKRENKNLQQEISDLTEQ 1521



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 74/358 (20%), Positives = 144/358 (40%), Gaps = 46/358 (12%)

Query: 132  QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
            ++  E+ + + A ++ L ++ A  + +  + +A+I  LE+Q+ D +   E  KK   DLE
Sbjct: 997  KLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIK-LEQQVDDLEGSLEQEKKLRMDLE 1055

Query: 192  QLVNRL--------------AIERSHATVKVKE-------LREQAETAEQVA---QSRVS 227
            +   +L                E+     K+K+       L+ + E  + +    Q ++ 
Sbjct: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIK 1115

Query: 228  EQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCL 287
            E +AR E L+ ++  +  S+A A                +L+     +   ++M ++R  
Sbjct: 1116 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175

Query: 288  EYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES 347
            E+   +     D E E   + + T   L +   +   S AE    +++L R+ Q    E 
Sbjct: 1176 EFQKMRR----DLE-EATLQHEATAATLRKKHAD---SVAELGEQIDNLQRVKQKLEKEK 1227

Query: 348  FQDKMATELLDREQKIV--------KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + KM  + L    + V        K+ +T+++Q    KS E+   +  N L A R  ++
Sbjct: 1228 SEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287

Query: 400  RLR---NYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
                  +     K+    +L         Q+E L R+    I A  A + AL   RH+
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345



 Score = 35.9 bits (79), Expect = 0.32
 Identities = 52/295 (17%), Positives = 126/295 (42%), Gaps = 18/295 (6%)

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +K ++ SAE+        +AT++ + +  K E   ++ K K+LE+ +  L  E++   ++
Sbjct: 842  IKPLLKSAET-----EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQ 896

Query: 208  VKE----LREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            V+     L +  E  +Q+ ++++ + +A+ + +  +  ++E+  A               
Sbjct: 897  VQAEAEGLADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 955

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
                +    + ++  V+ E+      V     E    +  I K  +  +      ++ L 
Sbjct: 956  LKKDIDDL-ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1014

Query: 324  QSRAEKDSFLNSL--SRIAQGEGTESFQDKMATE---LLDREQKIVKLQQTIDEQRENEK 378
              +AE+D  +N+L  ++I   +  +  +  +  E    +D E+   KL+  +   +E+  
Sbjct: 1015 DLQAEEDK-VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIM 1073

Query: 379  SMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
             +E    Q + +L     E+  L++     +     +LQ +I +L  ++E L  E
Sbjct: 1074 DIENEKQQLDEKLKKKEFEISNLQS-KIEDEQALGIQLQKKIKELQARIEELEEE 1127



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 11/181 (6%)

Query: 207  KVKELREQAETAEQVAQSRVSEQKARTEFL--QAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            K+K L + AET +++A  +   QK + E    +AK  E E+                   
Sbjct: 841  KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900

Query: 265  XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               L    +R  +L+  + +  LE    +  E  + E EI  EL   +  L   E+E  +
Sbjct: 901  AEGLADAEERCDQLIKTKIQ--LEAKIKEVTERAEDEEEINAELTAKKRKL---EDECSE 955

Query: 325  SRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
             + + D    +L+++  +   TE+    +  E+   ++ I KL +   E++  +++ +QT
Sbjct: 956  LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK---EKKALQEAHQQT 1012

Query: 384  M 384
            +
Sbjct: 1013 L 1013



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 38/236 (16%), Positives = 96/236 (40%), Gaps = 11/236 (4%)

Query: 173  LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQ 229
            LKDT+   + A +  +DL++ +  +    +    +++ELR   EQ E + ++A+  + + 
Sbjct: 1656 LKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1715

Query: 230  KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
              R + L  +      +K                   + ++  +++ + +        E 
Sbjct: 1716 SERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEEL 1775

Query: 290  VPCKENEPTDRETEIWKELQMT-RGALLRSEE-ELRQSRAEKDSFLNSLSRIAQGEGTES 347
               KE + +     + K ++ T +   LR +E E    +  K       +R+ + EG   
Sbjct: 1776 K--KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1833

Query: 348  FQDKMATE----LLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
             + K   E    L   E+++ +L    +E R+N   ++  + + + ++ + + + +
Sbjct: 1834 SEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAE 1889



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 54/275 (19%), Positives = 109/275 (39%), Gaps = 24/275 (8%)

Query: 67   ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQS 126
            E+LK ++      A +   + + +   +E+ ++   I + ++ + S++       H   +
Sbjct: 1671 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQL---LHTQNT 1727

Query: 127  GSYNYQV-LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLK---DTKAEFEI 182
               N +  L  ++S+ +   E + +   +AE   + A    A +  +LK   DT A  E 
Sbjct: 1728 SLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1787

Query: 183  AKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE 242
             KK   ++EQ V  L +           L E  + A +  + ++ + +AR   L+ +V  
Sbjct: 1788 MKK---NMEQTVKDLQL----------RLDEAEQLALKGGKKQIQKLEARVRELEGEVES 1834

Query: 243  QEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRET 302
            ++K  A A                Q +  R   +RL D+  +        K  +    E 
Sbjct: 1835 EQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKL---QAKVKSYKRQAEEA 1891

Query: 303  EIWKELQMTRGALLRSEEELRQSRAE-KDSFLNSL 336
            E      + +   L+ E E  + RA+  +S +N L
Sbjct: 1892 EEQSNTNLAKFRKLQHELEEAEERADIAESQVNKL 1926


>AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.
          Length = 1715

 Score = 45.2 bits (102), Expect = 5e-04
 Identities = 69/358 (19%), Positives = 148/358 (41%), Gaps = 23/358 (6%)

Query: 109  DETSKKENEEPPCHPVQSGSYNYQVLNEELS---KERAAREALKEVVASAESMLRVARAR 165
            D T   E     C    S   N+ +L E+L    K+  +   +++   S E +L + +  
Sbjct: 691  DLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNH 750

Query: 166  IATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVA 222
               L  ++K  + +  + +++  + +++ ++L  ++     ++  LR    Q E   + A
Sbjct: 751  CELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA 810

Query: 223  QS---RVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
             +   ++ EQ  R E    K  E ++   ++                Q+   R+ + R +
Sbjct: 811  DTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 870

Query: 280  DMERR-RCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSR 338
              E+  R L+      +    +E E+ ++   +  +    EE+     + K+S L     
Sbjct: 871  SREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEK---DLSHKNSMLQEEIA 927

Query: 339  IAQGE-GTESFQDKMATELLDREQKIVK-----LQQTIDEQRENEKSMEQTMTQYENQLA 392
            + + E  T   Q++   +    + KIVK     LQ+TI   ++NE+++ QT++QY  +L+
Sbjct: 928  MLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTI---KQNEETLTQTISQYNGRLS 984

Query: 393  ALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLER 450
             L  E   + N    ++  S   L+ E+   H ++     +R    T+     L  +R
Sbjct: 985  VLTAE-NAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQR 1041



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 79/381 (20%), Positives = 166/381 (43%), Gaps = 34/381 (8%)

Query: 87   RDTMIKKIERLQKENSILQHKVDET-SKKENEEPPCHPVQSGSYNY-QVLNEELSKERAA 144
            ++++ +++ +LQ EN +L+ ++D+  +K +N+E     +Q   +   Q L  E  K+   
Sbjct: 1134 QESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLL 1193

Query: 145  -REALKEVVASAESML-RVARARIATLERQLKDTKAEFEIAK--KKHKDLE---QLVNRL 197
              E  KE+++    +  R  +      ER++   + + E+A   KK    E   ++ +R 
Sbjct: 1194 LEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRY 1253

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXX 257
             I     T  +K+   Q     Q AQ R +E     E +Q    + EK  A         
Sbjct: 1254 RINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQ 1313

Query: 258  XXXXXXXXXQL------QSFRDRSIRLVDMERR-RCLEYVPCKENEPTDRETEIWKEL-Q 309
                      L      +  +++  +L+++++   C      K+N   +RE   +K L +
Sbjct: 1314 MDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLK 1373

Query: 310  MTRGALLRSEE-------ELRQSRAEKDSFLNSLSR-----IAQGE--GTESFQDKMATE 355
            MTR  L   E        +L+ S+ E D  +N L        A+ E  G++        +
Sbjct: 1374 MTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 1433

Query: 356  LLDREQKIVK-LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP 414
            +L  E   +K +Q+  ++ ++N+K +EQ +    + +    +E+ +++ Y    ++ +  
Sbjct: 1434 ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1493

Query: 415  ELQTEI--LDLHLQVETLSRE 433
            E+  ++  ++L LQ +  S+E
Sbjct: 1494 EIAEKLKEVNLFLQAQAASQE 1514


>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
            protein.
          Length = 1937

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 66/357 (18%), Positives = 146/357 (40%), Gaps = 23/357 (6%)

Query: 87   RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 1170 REAEFQKLRR-DLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK 1228

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
               + ++S    +  A+  +  + R L+D  +     K K ++ ++L+N L  +R+    
Sbjct: 1229 METDDLSSNAEAISKAKGHLEKMCRSLEDQVSGL---KTKEEEQQRLINDLTAQRARLQT 1285

Query: 207  KV----KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
            +     ++L EQ     Q+++S+ +  + + E L+ ++ E+ K+K               
Sbjct: 1286 EAGEYSRQLDEQDALVSQLSRSKQASTQ-QIEELKHQLEEETKAKNALAHALQSSRHDCD 1344

Query: 263  XXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSEE 320
                Q +  ++    L     +   E    +    TD  + TE  +E +      L+  E
Sbjct: 1345 LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAE 1404

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQREN 376
            E  ++   K + L    +  Q E  +   D      A   LD++Q+     + + E ++ 
Sbjct: 1405 EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQR--NFDKVLSEWKQK 1462

Query: 377  EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV------SYPELQTEILDLHLQV 427
             +  +  +   + +  +L  E+ +++N    S D       ++  LQ EI DL  Q+
Sbjct: 1463 YEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQI 1519



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 73/391 (18%), Positives = 158/391 (40%), Gaps = 29/391 (7%)

Query: 93   KIERLQKENSILQHKVDETSKK-ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEV 151
            K   L+K    LQ++V++     E     C  +     N+   ++ LS+ +   E  +  
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNF---DKVLSEWKQKYEETQAE 1469

Query: 152  VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
            + +++   R     +  ++   +++  + E  ++ HK+L+Q ++ L  + +    ++ EL
Sbjct: 1470 LEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHEL 1529

Query: 212  ---REQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL 268
               ++Q E  +   Q+ + E +A  E  + K+   +                      QL
Sbjct: 1530 EKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQL 1589

Query: 269  QSFRDRSIR----LVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
            +    R +      +D E R   + +  K+    D       E+Q+     L + E LR 
Sbjct: 1590 KRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNE---MEIQLNHANRL-AAESLRN 1645

Query: 325  SRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDR-----EQKIVKLQQTIDEQRENEK 378
             R  +     +   +     G E  ++++A  +++R     + +I +L  T+++   + K
Sbjct: 1646 YRNTQGILKETQLHLDDALRGQEDLKEQLA--IVERRANLLQAEIEELWATLEQTERSRK 1703

Query: 379  SMEQTMTQYENQLAALRLEVKRLRN-YDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
              EQ +     ++  L  +   L N       DVS  +LQ+E+ ++  +      +    
Sbjct: 1704 IAEQELLDASERVQLLHTQNTSLINTKKKLENDVS--QLQSEVEEVIQESRNAEEKAKKA 1761

Query: 438  ITAAASRALMLERHERAADLFARMVRARKDL 468
            IT A   A+M E  ++  D  A + R +K+L
Sbjct: 1762 ITDA---AMMAEELKKEQDTSAHLERMKKNL 1789



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 58/294 (19%), Positives = 123/294 (41%), Gaps = 16/294 (5%)

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +K ++ SAE+        +AT++ + + TK E   ++ K K+LE+ +  L  E++   ++
Sbjct: 839  IKPLLKSAET-----EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQ 893

Query: 208  VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ-EKSKAVAXXXXXXXXXXXXXXXX 266
            V+   +    AE+  +  + + K + E    +V E+ E+ + +                 
Sbjct: 894  VQSEADSLADAEERCEQLI-KNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 952

Query: 267  QLQSFRDRSIRLVDMERRRCLEYVPCKE-NEPTDRETEIWKELQMTRGALLRSEEE-LRQ 324
              +   D  + L  +E+++       K   E      E   +L   + AL  + ++ L  
Sbjct: 953  LKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDD 1012

Query: 325  SRAEKDSFLNSLSRI-----AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
             +AE+D  +N L++       Q +  E   ++     +D E+   KL+  +   +E+   
Sbjct: 1013 LQAEEDK-VNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMD 1071

Query: 380  MEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            ME    Q + +L     E+  L +     +     +LQ +I +L  ++E L  E
Sbjct: 1072 MENDKQQLDEKLEKKEFEISNLIS-KIEDEQAVEIQLQKKIKELQARIEELGEE 1124



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 47/252 (18%), Positives = 102/252 (40%), Gaps = 11/252 (4%)

Query: 207  KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX 266
            K+K L + AET +++A  +   QK + E  +++   +E  + +                 
Sbjct: 838  KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMV-TLLKEKNDLQLQVQS 896

Query: 267  QLQSFRDRSIRLVDMERRRCLEYVPCKE-NEPTDRETEIWKELQMTRGALLRSEEELRQS 325
            +  S  D   R   + + +       KE  E  + E EI  EL   +  L   E+E  + 
Sbjct: 897  EADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKL---EDECSEL 953

Query: 326  RAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTM 384
            + + D    +L+++  Q   TE+    +  E+   ++ I KL +   E++  +++ +QT+
Sbjct: 954  KKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSK---EKKALQETHQQTL 1010

Query: 385  TQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASR 444
               + +   + +  K     +    D+    L+ E   L + +E   R+    +  A   
Sbjct: 1011 DDLQAEEDKVNILTKAKTKLEQQVDDLE-GSLEQE-KKLRMDLERAKRKLEGDLKLAQES 1068

Query: 445  ALMLERHERAAD 456
             + +E  ++  D
Sbjct: 1069 TMDMENDKQQLD 1080



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 77/426 (18%), Positives = 177/426 (41%), Gaps = 38/426 (8%)

Query: 56   ERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDET---- 111
            ER  +++    + L+AKI    E A+        +  K  +L+ E S L+  +D+     
Sbjct: 906  ERCEQLIKNKIQ-LEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTL 964

Query: 112  SKKENEEPPC-HPVQSGSYNYQVLNEELSKERAAREALKEV-------VASAESMLRVAR 163
            +K E ++    + V++ +     L+E ++K    ++AL+E        + + E  + +  
Sbjct: 965  AKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILT 1024

Query: 164  ARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIE---RSHATVKVKELREQAETAEQ 220
                 LE+Q+ D +   E  KK   DLE+   +L  +      +T+ ++  ++Q +   +
Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLE 1084

Query: 221  VAQSRVSEQKARTEFLQA-KVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLV 279
              +  +S   ++ E  QA ++  Q+K K +                 + ++ + RS    
Sbjct: 1085 KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS---- 1140

Query: 280  DMERRRCLEYVPCKENEPTDRETEIWKELQMTRGA-LLRSEEELRQSRAEKDSFLNSLSR 338
            D+ R   LE +  +  E     T    EL   R A   +   +L ++  + ++ + +L +
Sbjct: 1141 DLSRE--LEEI-SERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRK 1197

Query: 339  IAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
                       D MA EL ++   + +++Q +++++   K     ++     ++  +  +
Sbjct: 1198 --------KHADSMA-ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHL 1248

Query: 399  KRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLF 458
            +++    C S +     L+T+  +    +  L+ +R  L T A   +  L+  +      
Sbjct: 1249 EKM----CRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQL 1304

Query: 459  ARMVRA 464
            +R  +A
Sbjct: 1305 SRSKQA 1310



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 54/254 (21%), Positives = 114/254 (44%), Gaps = 19/254 (7%)

Query: 2    RKNLIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRM 61
            R NL+  Q  + E +A L   E    +A + L +      L   T+NT   N  ++L   
Sbjct: 1680 RANLL--QAEIEELWATLEQTERSRKIAEQELLDASERVQL-LHTQNTSLINTKKKLEND 1736

Query: 62   VAGIAENLKAKINFSL---EIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEE 118
            V+ +   ++  I  S    E AK    D   M +++++ Q  ++ L+ ++ +  ++  ++
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE-RMKKNLEQTVKD 1795

Query: 119  PPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKA 178
                  ++     +   +++ K  A    L+  V + +     A   +   +R++K+   
Sbjct: 1796 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHDRRVKELTY 1855

Query: 179  EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSE-QKARTEFLQ 237
            + E  +K    L+ LV++L         KVK  + QAE AE+ + + +S+ +K + E  +
Sbjct: 1856 QTEEDRKNVLRLQDLVDKLQ-------AKVKSYKRQAEEAEEQSNANLSKFRKLQHELEE 1908

Query: 238  AK----VAEQEKSK 247
            A+    +AE + +K
Sbjct: 1909 AEERADIAESQVNK 1922


>BC112121-1|AAI12122.1|  478|Homo sapiens growth arrest-specific 8
           protein.
          Length = 478

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 68/342 (19%), Positives = 136/342 (39%), Gaps = 27/342 (7%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKH----KD 189
           + EEL +ER  R   +       +   + R ++   + +L++   E E A+++H    K 
Sbjct: 38  IREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKV 97

Query: 190 LEQLVNRLAIERSHATVKVKELREQAETAEQVAQS--RVSEQKARTEFLQAKVAEQEKSK 247
            +Q V  L  E  +    + E++ +     ++AQ   R+ E   R +    KV  +E+  
Sbjct: 98  YKQKVKHLLYEHQN---NLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQEL 154

Query: 248 AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE 307
           A                      F +R +R ++ +  + ++ +  ++     R+TE+ + 
Sbjct: 155 ASEVVVKNLRLKHTEEITRMRNDF-ERQVREIEAKYDKKMKML--RDELDLRRKTELHEV 211

Query: 308 LQMTRG---ALLRSEEELRQ--SRAEKDSFLNSLSRI----AQGEGTESFQDKMATELLD 358
            +   G    L++  EE          D  LN+L+ I     Q E     +D +  E+ +
Sbjct: 212 EERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAE 271

Query: 359 REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE--L 416
              +  +L   + + RE    M++ +  YE     L     RL+  +   KD+ +    L
Sbjct: 272 VSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEHEVL 331

Query: 417 QTEILDLHLQVETLSRERTALITAAASRA----LMLERHERA 454
           +     +  + + L R+ TA I     +     L+LER  +A
Sbjct: 332 EQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQA 373


>BC104785-1|AAI04786.1|  478|Homo sapiens growth arrest-specific 8
           protein.
          Length = 478

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 68/342 (19%), Positives = 136/342 (39%), Gaps = 27/342 (7%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKH----KD 189
           + EEL +ER  R   +       +   + R ++   + +L++   E E A+++H    K 
Sbjct: 38  IREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKV 97

Query: 190 LEQLVNRLAIERSHATVKVKELREQAETAEQVAQS--RVSEQKARTEFLQAKVAEQEKSK 247
            +Q V  L  E  +    + E++ +     ++AQ   R+ E   R +    KV  +E+  
Sbjct: 98  YKQKVKHLLYEHQN---NLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQEL 154

Query: 248 AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE 307
           A                      F +R +R ++ +  + ++ +  ++     R+TE+ + 
Sbjct: 155 ASEVVVKNLRLKHTEEITRMRNDF-ERQVREIEAKYDKKMKML--RDELDLRRKTELHEV 211

Query: 308 LQMTRG---ALLRSEEELRQ--SRAEKDSFLNSLSRI----AQGEGTESFQDKMATELLD 358
            +   G    L++  EE          D  LN+L+ I     Q E     +D +  E+ +
Sbjct: 212 EERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAE 271

Query: 359 REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE--L 416
              +  +L   + + RE    M++ +  YE     L     RL+  +   KD+ +    L
Sbjct: 272 VSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEHEVL 331

Query: 417 QTEILDLHLQVETLSRERTALITAAASRA----LMLERHERA 454
           +     +  + + L R+ TA I     +     L+LER  +A
Sbjct: 332 EQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQA 373


>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
           protein.
          Length = 1492

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 66/350 (18%), Positives = 145/350 (41%), Gaps = 22/350 (6%)

Query: 92  KKIERLQKENSILQHKV---DETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
           KK E    + S LQ K+   +    K+ E      +Q      + LN ++ +E      L
Sbjct: 289 KKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLEL 348

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL--AIE----RS 202
           K+ + +A+ +L   + +I    +++K+ K E   +K+K +   + + +L   +E    R+
Sbjct: 349 KDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRN 408

Query: 203 HATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
           H   + +   +  +  EQ  Q ++ + +A  + +  +   Q K + +             
Sbjct: 409 HKDSQFE--TDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 466

Query: 263 XXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN---EPTDRETEIWKE----LQMTRGAL 315
                  + R  S   V+ ++ + +     + N   + T+ + E  KE    +   + AL
Sbjct: 467 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 526

Query: 316 LRSEEELRQSRA-EKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            R  E+L +  +  ++    +   IA+ E   +   K  + + D + +IV   ++   ++
Sbjct: 527 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASES---RK 583

Query: 375 ENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
           E E   E  +T Y+ +L  L  E   + +    S++     L+T++L  H
Sbjct: 584 ELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSH 633



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 92/444 (20%), Positives = 185/444 (41%), Gaps = 42/444 (9%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIK----KIERLQKENSILQ 105
           E ++     H+ ++ + E+LKA+I  + E  K   L  +  +     K+E L+KE + + 
Sbjct: 553 EQESKLNEAHKSLSTV-EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVL 611

Query: 106 HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE-RAAREALKEVVA-----SAESML 159
            ++ E+ + E E      + S       L E+L  E R   E LK+ +        + + 
Sbjct: 612 DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ 671

Query: 160 RVARARIATLERQLKD--TKAEFEIAK-KKHKDLEQ-LVNRLAIERS---HATVKVKELR 212
                +I T++ +  +  TK    I +  K KDL+Q LVN  + E +   +   K  E+ 
Sbjct: 672 NEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEIL 731

Query: 213 EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            Q E  +   +  V E + +TE L+ ++ E+E                       L+   
Sbjct: 732 RQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 791

Query: 273 DRSIRLVDMERRRCLEYVPCKENEPTDRETEIW-KELQMTRGALLRSEEELRQSRAEKDS 331
                +   ER   L+ +  K  +       +W KE+++    L+   E+L+Q   +   
Sbjct: 792 KIHTPVSQEERLIFLDSIKSKSKD------SVWEKEIEI----LIEENEDLKQQCIQ--- 838

Query: 332 FLNSLSRIAQGEGTESFQDK-MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
            LN    I +   T SF +K       + +++   L +  D+  +++   E    +Y+++
Sbjct: 839 -LN--EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE---LEYKSK 892

Query: 391 LAAL--RLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALI-TAAASRALM 447
           L AL   L ++R+       K   + E +T + +     E + ++ T L+     ++   
Sbjct: 893 LKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREK 952

Query: 448 LERHERAADLFARMVRARKDLAAL 471
           LE  +R +DL  ++ +   +++ L
Sbjct: 953 LELSQRLSDLSEQLKQKHGEISFL 976


>AK131384-1|BAD18535.1|  326|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16459 fis, clone BRCAN2002473, moderately
           similar to Tropomyosin, fibroblast isoform 2. ).
          Length = 326

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 49/253 (19%), Positives = 102/253 (40%), Gaps = 10/253 (3%)

Query: 138 LSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL 197
           L+ E AA + L++ + S +  L+     +      LKD + + E+A+KK  D E  V  L
Sbjct: 72  LAAEEAAAK-LEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASL 130

Query: 198 AIERSHATVKVKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXX 254
                    ++   +E+  TA Q    A+    E +   + ++++  + E+   +     
Sbjct: 131 NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQL 190

Query: 255 XXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGA 314
                       + +    R + +++ +  R  E     E +  + E E+ K +     +
Sbjct: 191 KEAKHIAEDADRKYEEVA-RKLVIIESDLERAEERAELSEGKCAELEEEL-KTVTNNLKS 248

Query: 315 LLRSEEELRQSRAEKDSFLNSLS-RIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
           L    E+  Q     +  +  LS ++ + E    F ++  T+L   E+ I  L++ +   
Sbjct: 249 LEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKL---EKSIDDLEEKVAHA 305

Query: 374 RENEKSMEQTMTQ 386
           +E   SM Q + Q
Sbjct: 306 KEENLSMHQMLDQ 318



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 49/234 (20%), Positives = 104/234 (44%), Gaps = 16/234 (6%)

Query: 207 KVKELREQAETAEQVAQSRVSEQKA---RTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
           K++ L+   E A   A+   +++KA   R++ L+  +A +EK   V+             
Sbjct: 7   KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHK 66

Query: 264 XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
               L +  + + +L D E     + +   E+E  D+ +E  K+ Q     L  +E++  
Sbjct: 67  AEDSLLAAEEAAAKLED-ELVSLQKKLKGTEDE-LDKYSEALKDAQEK---LELAEKKAT 121

Query: 324 QSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
            + A+  S LN   ++ + E  +  Q+++AT L    QK+ + ++  DE     K +E  
Sbjct: 122 DAEADVAS-LNRRIQLVEEE-LDRAQERLATAL----QKLEEAEKAADESERGMKVIESR 175

Query: 384 MTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
             + E ++    +++K  ++      D  Y E+  +++ +   +E  + ER  L
Sbjct: 176 AQKDEEKMEIQEIQLKEAKHI-AEDADRKYEEVARKLVIIESDLER-AEERAEL 227


>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
          Length = 3908

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 66/350 (18%), Positives = 145/350 (41%), Gaps = 22/350 (6%)

Query: 92  KKIERLQKENSILQHKV---DETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
           KK E    + S LQ K+   +    K+ E      +Q      + LN ++ +E      L
Sbjct: 289 KKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLEL 348

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL--AIE----RS 202
           K+ + +A+ +L   + +I    +++K+ K E   +K+K +   + + +L   +E    R+
Sbjct: 349 KDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRN 408

Query: 203 HATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
           H   + +   +  +  EQ  Q ++ + +A  + +  +   Q K + +             
Sbjct: 409 HKDSQFE--TDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 466

Query: 263 XXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN---EPTDRETEIWKE----LQMTRGAL 315
                  + R  S   V+ ++ + +     + N   + T+ + E  KE    +   + AL
Sbjct: 467 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 526

Query: 316 LRSEEELRQSRA-EKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            R  E+L +  +  ++    +   IA+ E   +   K  + + D + +IV   ++   ++
Sbjct: 527 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASES---RK 583

Query: 375 ENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
           E E   E  +T Y+ +L  L  E   + +    S++     L+T++L  H
Sbjct: 584 ELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSH 633



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 91/430 (21%), Positives = 178/430 (41%), Gaps = 42/430 (9%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIK----KIERLQKENSILQ 105
           E ++     H+ ++ + E+LKA+I  + E  K   L  +  +     K+E L+KE + + 
Sbjct: 553 EQESKLNEAHKSLSTV-EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVL 611

Query: 106 HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE-RAAREALKEVVA-----SAESML 159
            ++ E+ + E E      + S       L E+L  E R   E LK+ +        + + 
Sbjct: 612 DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ 671

Query: 160 RVARARIATLERQLKD--TKAEFEIAK-KKHKDLEQ-LVNRLAIERS---HATVKVKELR 212
                +I T++ +  +  TK    I +  K KDL+Q LVN  + E +   +   K  E+ 
Sbjct: 672 NEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEIL 731

Query: 213 EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            Q E  +   +  V E + +TE L+ ++ E+E                       L+   
Sbjct: 732 RQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 791

Query: 273 DRSIRLVDMERRRCLEYVPCKENEPTDRETEIW-KELQMTRGALLRSEEELRQSRAEKDS 331
                +   ER   L+ +  K  +       +W KE+++    L+   E+L+Q   +   
Sbjct: 792 KIHTPVSQEERLIFLDSIKSKSKD------SVWEKEIEI----LIEENEDLKQQCIQ--- 838

Query: 332 FLNSLSRIAQGEGTESFQDK-MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
            LN    I +   T SF +K       + +++   L +  D+  +++   E    +Y+++
Sbjct: 839 -LN--EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE---LEYKSK 892

Query: 391 LAAL--RLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALI-TAAASRALM 447
           L AL   L ++R+       K   + E +T + +     E + ++ T L+     ++   
Sbjct: 893 LKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREK 952

Query: 448 LERHERAADL 457
           LE  +R +DL
Sbjct: 953 LELSQRLSDL 962



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 80/343 (23%), Positives = 141/343 (41%), Gaps = 28/343 (8%)

Query: 97   LQKENSILQHKVDETSKK--ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
            LQK+   L+  V+E   +  E E+     +       Q L ++L K    R+ L E    
Sbjct: 2020 LQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK---MRKFLDEQAID 2076

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E    V +  I  LE+QLK       I++ + +++EQL N       H   K  +  E 
Sbjct: 2077 REHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLAN-------HLKEKTDKCSEL 2129

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
              + EQ+ Q  + E+    E L+ +V E E++  V+                + +     
Sbjct: 2130 LLSKEQL-QRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSL 2188

Query: 275  SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD-SFL 333
             ++L   ER    + +  KE E T+ E    ++L+  R  L    EE++Q   + +    
Sbjct: 2189 EVQL-QAER----DAIDRKEKEITNLE----EQLEQFREELENKNEEVQQLHMQLEIQKK 2239

Query: 334  NSLSRIAQGE-GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLA 392
             S +R+ + E   + F+D M  E L    K      T D+     K   Q + + E ++ 
Sbjct: 2240 ESTTRLQELEQENKLFKDDM--EKLGLAIKESDAMSTQDQHVLFGK-FAQIIQEKEVEID 2296

Query: 393  ALRLEVKRLRNYDCYSKDVSYPELQTEIL-DLHLQVETLSRER 434
             L  +V +L+     + D    E + E++ DL  Q+E L  ++
Sbjct: 2297 QLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQ 2339



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 67/354 (18%), Positives = 146/354 (41%), Gaps = 20/354 (5%)

Query: 92   KKIERLQKENSILQH-KVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
            K +E + + +S L+H KV +T                    + L E L +E  ARE L  
Sbjct: 1857 KLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAV 1916

Query: 151  VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHATV-KV 208
             ++ AE ++          ERQ+++   + +I  +  ++L    NRL  +E     + + 
Sbjct: 1917 ELSKAEGVIDGYADEKTLFERQIQE---KTDIIDRLEQELLCASNRLQELEAEQQQIQEE 1973

Query: 209  KELREQAETAEQVAQSRVSEQ--KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX 266
            +EL  + + A +     V +Q  +   + ++ K+  Q +++ V                 
Sbjct: 1974 RELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEE 2033

Query: 267  QLQSF----RDRSIRLVDM-ERRRCLEYVPCKENEPTDRET-EIWKELQMTRGALLRSEE 320
            Q+  F    ++++  L+D+ ++ + LE    K  +  D +  +   E  + +  + + E+
Sbjct: 2034 QVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQ 2093

Query: 321  ELRQSRAEKDSFLNSLSRIAQ-GEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
            +L+     +    +    + Q     +   DK +  LL +EQ    LQ+ I E+ E  + 
Sbjct: 2094 QLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQ----LQRDIQERNEEIEK 2149

Query: 380  MEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            +E  + + E  L       +++ +   +    + PEL  E+  L  + + + R+
Sbjct: 2150 LEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEV-QLQAERDAIDRK 2202



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 30/133 (22%), Positives = 59/133 (44%), Gaps = 3/133 (2%)

Query: 308  LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
            L  ++G  + SE    +S +  DSF   +  + +    E  Q    TE    + +   +Q
Sbjct: 2916 LTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQ 2975

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
            Q  +   E  K+   T++  ++ +  ++L+ +    YD      S+ + + E+L L LQ 
Sbjct: 2976 QVSEPWLEERKAYINTISSLKDLITKMQLQ-REAEVYDSSQSHESFSDWRGELL-LALQ- 3032

Query: 428  ETLSRERTALITA 440
            +    ER+ L+ A
Sbjct: 3033 QVFLEERSVLLAA 3045


>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
          Length = 3911

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 66/350 (18%), Positives = 145/350 (41%), Gaps = 22/350 (6%)

Query: 92  KKIERLQKENSILQHKV---DETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
           KK E    + S LQ K+   +    K+ E      +Q      + LN ++ +E      L
Sbjct: 301 KKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLEL 360

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL--AIE----RS 202
           K+ + +A+ +L   + +I    +++K+ K E   +K+K +   + + +L   +E    R+
Sbjct: 361 KDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRN 420

Query: 203 HATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
           H   + +   +  +  EQ  Q ++ + +A  + +  +   Q K + +             
Sbjct: 421 HKDSQFE--TDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 478

Query: 263 XXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN---EPTDRETEIWKE----LQMTRGAL 315
                  + R  S   V+ ++ + +     + N   + T+ + E  KE    +   + AL
Sbjct: 479 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 538

Query: 316 LRSEEELRQSRA-EKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            R  E+L +  +  ++    +   IA+ E   +   K  + + D + +IV   ++   ++
Sbjct: 539 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASES---RK 595

Query: 375 ENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
           E E   E  +T Y+ +L  L  E   + +    S++     L+T++L  H
Sbjct: 596 ELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSH 645



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 92/444 (20%), Positives = 185/444 (41%), Gaps = 42/444 (9%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIK----KIERLQKENSILQ 105
           E ++     H+ ++ + E+LKA+I  + E  K   L  +  +     K+E L+KE + + 
Sbjct: 565 EQESKLNEAHKSLSTV-EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVL 623

Query: 106 HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE-RAAREALKEVVA-----SAESML 159
            ++ E+ + E E      + S       L E+L  E R   E LK+ +        + + 
Sbjct: 624 DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ 683

Query: 160 RVARARIATLERQLKD--TKAEFEIAK-KKHKDLEQ-LVNRLAIERS---HATVKVKELR 212
                +I T++ +  +  TK    I +  K KDL+Q LVN  + E +   +   K  E+ 
Sbjct: 684 NEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEIL 743

Query: 213 EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            Q E  +   +  V E + +TE L+ ++ E+E                       L+   
Sbjct: 744 RQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 803

Query: 273 DRSIRLVDMERRRCLEYVPCKENEPTDRETEIW-KELQMTRGALLRSEEELRQSRAEKDS 331
                +   ER   L+ +  K  +       +W KE+++    L+   E+L+Q   +   
Sbjct: 804 KIHTPVSQEERLIFLDSIKSKSKD------SVWEKEIEI----LIEENEDLKQQCIQ--- 850

Query: 332 FLNSLSRIAQGEGTESFQDK-MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
            LN    I +   T SF +K       + +++   L +  D+  +++   E    +Y+++
Sbjct: 851 -LN--EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE---LEYKSK 904

Query: 391 LAAL--RLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALI-TAAASRALM 447
           L AL   L ++R+       K   + E +T + +     E + ++ T L+     ++   
Sbjct: 905 LKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREK 964

Query: 448 LERHERAADLFARMVRARKDLAAL 471
           LE  +R +DL  ++ +   +++ L
Sbjct: 965 LELSQRLSDLSEQLKQKHGEISFL 988



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 80/343 (23%), Positives = 141/343 (41%), Gaps = 28/343 (8%)

Query: 97   LQKENSILQHKVDETSKK--ENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
            LQK+   L+  V+E   +  E E+     +       Q L ++L K    R+ L E    
Sbjct: 2031 LQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK---MRKFLDEQAID 2087

Query: 155  AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             E    V +  I  LE+QLK       I++ + +++EQL N       H   K  +  E 
Sbjct: 2088 REHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLAN-------HLKEKTDKCSEL 2140

Query: 215  AETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDR 274
              + EQ+ Q  + E+    E L+ +V E E++  V+                + +     
Sbjct: 2141 LLSKEQL-QRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSL 2199

Query: 275  SIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKD-SFL 333
             ++L   ER    + +  KE E T+ E    ++L+  R  L    EE++Q   + +    
Sbjct: 2200 EVQL-QAER----DAIDRKEKEITNLE----EQLEQFREELENKNEEVQQLHMQLEIQKK 2250

Query: 334  NSLSRIAQGE-GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLA 392
             S +R+ + E   + F+D M  E L    K      T D+     K   Q + + E ++ 
Sbjct: 2251 ESTTRLQELEQENKLFKDDM--EKLGLAIKESDAMSTQDQHVLFGK-FAQIIQEKEVEID 2307

Query: 393  ALRLEVKRLRNYDCYSKDVSYPELQTEIL-DLHLQVETLSRER 434
             L  +V +L+     + D    E + E++ DL  Q+E L  ++
Sbjct: 2308 QLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQ 2350



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 67/354 (18%), Positives = 146/354 (41%), Gaps = 20/354 (5%)

Query: 92   KKIERLQKENSILQH-KVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
            K +E + + +S L+H KV +T                    + L E L +E  ARE L  
Sbjct: 1868 KLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAV 1927

Query: 151  VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL-AIERSHATV-KV 208
             ++ AE ++          ERQ+++   + +I  +  ++L    NRL  +E     + + 
Sbjct: 1928 ELSKAEGVIDGYADEKTLFERQIQE---KTDIIDRLEQELLCASNRLQELEAEQQQIQEE 1984

Query: 209  KELREQAETAEQVAQSRVSEQ--KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX 266
            +EL  + + A +     V +Q  +   + ++ K+  Q +++ V                 
Sbjct: 1985 RELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEE 2044

Query: 267  QLQSF----RDRSIRLVDM-ERRRCLEYVPCKENEPTDRET-EIWKELQMTRGALLRSEE 320
            Q+  F    ++++  L+D+ ++ + LE    K  +  D +  +   E  + +  + + E+
Sbjct: 2045 QVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQ 2104

Query: 321  ELRQSRAEKDSFLNSLSRIAQ-GEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
            +L+     +    +    + Q     +   DK +  LL +EQ    LQ+ I E+ E  + 
Sbjct: 2105 QLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQ----LQRDIQERNEEIEK 2160

Query: 380  MEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            +E  + + E  L       +++ +   +    + PEL  E+  L  + + + R+
Sbjct: 2161 LEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEV-QLQAERDAIDRK 2213



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 30/133 (22%), Positives = 59/133 (44%), Gaps = 3/133 (2%)

Query: 308  LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
            L  ++G  + SE    +S +  DSF   +  + +    E  Q    TE    + +   +Q
Sbjct: 2919 LTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQ 2978

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
            Q  +   E  K+   T++  ++ +  ++L+ +    YD      S+ + + E+L L LQ 
Sbjct: 2979 QVSEPWLEERKAYINTISSLKDLITKMQLQ-REAEVYDSSQSHESFSDWRGELL-LALQ- 3035

Query: 428  ETLSRERTALITA 440
            +    ER+ L+ A
Sbjct: 3036 QVFLEERSVLLAA 3048


>AF050079-1|AAC69519.1|  478|Homo sapiens growth arrest specific 11
           protein.
          Length = 478

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 68/342 (19%), Positives = 136/342 (39%), Gaps = 27/342 (7%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKH----KD 189
           + EEL +ER  R   +       +   + R ++   + +L++   E E A+++H    K 
Sbjct: 38  IREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKV 97

Query: 190 LEQLVNRLAIERSHATVKVKELREQAETAEQVAQS--RVSEQKARTEFLQAKVAEQEKSK 247
            +Q V  L  E  +    + E++ +     ++AQ   R+ E   R +    KV  +E+  
Sbjct: 98  YKQKVKHLLYEHQN---NLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQEL 154

Query: 248 AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE 307
           A                      F +R +R ++ +  + ++ +  ++     R+TE+ + 
Sbjct: 155 ASEVVVKNLRLKHTEEITRMRNDF-ERQVREIEAKYDKKMKML--RDELDLRRKTELHEV 211

Query: 308 LQMTRG---ALLRSEEELRQ--SRAEKDSFLNSLSRI----AQGEGTESFQDKMATELLD 358
            +   G    L++  EE          D  LN+L+ I     Q E     +D +  E+ +
Sbjct: 212 EERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAE 271

Query: 359 REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE--L 416
              +  +L   + + RE    M++ +  YE     L     RL+  +   KD+ +    L
Sbjct: 272 VSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEHEVL 331

Query: 417 QTEILDLHLQVETLSRERTALITAAASRA----LMLERHERA 454
           +     +  + + L R+ TA I     +     L+LER  +A
Sbjct: 332 EQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQA 373


>AF050078-1|AAC69518.1|  478|Homo sapiens growth arrest specific 11
           protein.
          Length = 478

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 68/342 (19%), Positives = 136/342 (39%), Gaps = 27/342 (7%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKH----KD 189
           + EEL +ER  R   +       +   + R ++   + +L++   E E A+++H    K 
Sbjct: 38  IREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKV 97

Query: 190 LEQLVNRLAIERSHATVKVKELREQAETAEQVAQS--RVSEQKARTEFLQAKVAEQEKSK 247
            +Q V  L  E  +    + E++ +     ++AQ   R+ E   R +    KV  +E+  
Sbjct: 98  YKQKVKHLLYEHQN---NLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQEL 154

Query: 248 AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE 307
           A                      F +R +R ++ +  + ++ +  ++     R+TE+ + 
Sbjct: 155 ASEVVVKNLRLKHTEEITRMRNDF-ERQVREIEAKYDKKMKML--RDELDLRRKTELHEV 211

Query: 308 LQMTRG---ALLRSEEELRQ--SRAEKDSFLNSLSRI----AQGEGTESFQDKMATELLD 358
            +   G    L++  EE          D  LN+L+ I     Q E     +D +  E+ +
Sbjct: 212 EERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAE 271

Query: 359 REQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE--L 416
              +  +L   + + RE    M++ +  YE     L     RL+  +   KD+ +    L
Sbjct: 272 VSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEHEVL 331

Query: 417 QTEILDLHLQVETLSRERTALITAAASRA----LMLERHERA 454
           +     +  + + L R+ TA I     +     L+LER  +A
Sbjct: 332 EQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQA 373


>AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein.
          Length = 1642

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 66/350 (18%), Positives = 145/350 (41%), Gaps = 22/350 (6%)

Query: 92  KKIERLQKENSILQHKV---DETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
           KK E    + S LQ K+   +    K+ E      +Q      + LN ++ +E      L
Sbjct: 301 KKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLEL 360

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL--AIE----RS 202
           K+ + +A+ +L   + +I    +++K+ K E   +K+K +   + + +L   +E    R+
Sbjct: 361 KDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRN 420

Query: 203 HATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
           H   + +   +  +  EQ  Q ++ + +A  + +  +   Q K + +             
Sbjct: 421 HKDSQFE--TDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 478

Query: 263 XXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN---EPTDRETEIWKE----LQMTRGAL 315
                  + R  S   V+ ++ + +     + N   + T+ + E  KE    +   + AL
Sbjct: 479 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 538

Query: 316 LRSEEELRQSRA-EKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            R  E+L +  +  ++    +   IA+ E   +   K  + + D + +IV   ++   ++
Sbjct: 539 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASES---RK 595

Query: 375 ENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
           E E   E  +T Y+ +L  L  E   + +    S++     L+T++L  H
Sbjct: 596 ELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSH 645



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 91/430 (21%), Positives = 177/430 (41%), Gaps = 42/430 (9%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIK----KIERLQKENSILQ 105
           E ++     H+ ++ + E+LKA+I  + E  K   L  +  +     K+E L+KE + + 
Sbjct: 565 EQESKLNEAHKSLSTV-EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVL 623

Query: 106 HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE-RAAREALKEVVA-----SAESML 159
            ++ E+ + E E      + S       L E+L  E R   E LK+ +        + + 
Sbjct: 624 DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ 683

Query: 160 RVARARIATLERQLKD--TKAEFEIAK-KKHKDLEQ-LVNRLAIERS---HATVKVKELR 212
                +I T++ +  +  TK    I +  K KDL+Q LVN  + E +   +   K  E+ 
Sbjct: 684 NEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEIL 743

Query: 213 EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            Q E  +   +  V E + +TE L+ ++ E+E                       L+   
Sbjct: 744 RQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 803

Query: 273 DRSIRLVDMERRRCLEYVPCKENEPTDRETEIW-KELQMTRGALLRSEEELRQSRAEKDS 331
                +   ER   L+ +  K  +       +W KE+++    L+   E+L+Q   +   
Sbjct: 804 KIHTPVSQEERLIFLDSIKSKSKD------SVWEKEIEI----LIEENEDLKQQCIQ--- 850

Query: 332 FLNSLSRIAQGEGTESFQDK-MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
            LN    I +   T SF +K       + +++   L +  D+  +++   E    +Y+++
Sbjct: 851 -LN--EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE---LEYKSK 904

Query: 391 LAAL--RLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALI-TAAASRALM 447
           L AL   L ++R+       K   + E +T + +     E   ++ T L+     ++   
Sbjct: 905 LKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVXEKDTTELMEKLEVTKREK 964

Query: 448 LERHERAADL 457
           LE  +R +DL
Sbjct: 965 LELSQRLSDL 974


>AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein.
          Length = 1620

 Score = 44.8 bits (101), Expect = 7e-04
 Identities = 66/350 (18%), Positives = 145/350 (41%), Gaps = 22/350 (6%)

Query: 92  KKIERLQKENSILQHKV---DETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREAL 148
           KK E    + S LQ K+   +    K+ E      +Q      + LN ++ +E      L
Sbjct: 270 KKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLEL 329

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL--AIE----RS 202
           K+ + +A+ +L   + +I    +++K+ K E   +K+K +   + + +L   +E    R+
Sbjct: 330 KDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRN 389

Query: 203 HATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
           H   + +   +  +  EQ  Q ++ + +A  + +  +   Q K + +             
Sbjct: 390 HKDSQFE--TDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 447

Query: 263 XXXXQLQSFRDRSIRLVDMERRRCLEYVPCKEN---EPTDRETEIWKE----LQMTRGAL 315
                  + R  S   V+ ++ + +     + N   + T+ + E  KE    +   + AL
Sbjct: 448 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 507

Query: 316 LRSEEELRQSRA-EKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
            R  E+L +  +  ++    +   IA+ E   +   K  + + D + +IV   ++   ++
Sbjct: 508 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASES---RK 564

Query: 375 ENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
           E E   E  +T Y+ +L  L  E   + +    S++     L+T++L  H
Sbjct: 565 ELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSH 614



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 92/444 (20%), Positives = 185/444 (41%), Gaps = 42/444 (9%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIK----KIERLQKENSILQ 105
           E ++     H+ ++ + E+LKA+I  + E  K   L  +  +     K+E L+KE + + 
Sbjct: 534 EQESKLNEAHKSLSTV-EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVL 592

Query: 106 HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE-RAAREALKEVVA-----SAESML 159
            ++ E+ + E E      + S       L E+L  E R   E LK+ +        + + 
Sbjct: 593 DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ 652

Query: 160 RVARARIATLERQLKD--TKAEFEIAK-KKHKDLEQ-LVNRLAIERS---HATVKVKELR 212
                +I T++ +  +  TK    I +  K KDL+Q LVN  + E +   +   K  E+ 
Sbjct: 653 NEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEIL 712

Query: 213 EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            Q E  +   +  V E + +TE L+ ++ E+E                       L+   
Sbjct: 713 RQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 772

Query: 273 DRSIRLVDMERRRCLEYVPCKENEPTDRETEIW-KELQMTRGALLRSEEELRQSRAEKDS 331
                +   ER   L+ +  K  +       +W KE+++    L+   E+L+Q   +   
Sbjct: 773 KIHTPVSQEERLIFLDSIKSKSKD------SVWEKEIEI----LIEENEDLKQQCIQ--- 819

Query: 332 FLNSLSRIAQGEGTESFQDK-MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
            LN    I +   T SF +K       + +++   L +  D+  +++   E    +Y+++
Sbjct: 820 -LN--EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE---LEYKSK 873

Query: 391 LAAL--RLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALI-TAAASRALM 447
           L AL   L ++R+       K   + E +T + +     E + ++ T L+     ++   
Sbjct: 874 LKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREK 933

Query: 448 LERHERAADLFARMVRARKDLAAL 471
           LE  +R +DL  ++ +   +++ L
Sbjct: 934 LELSQRLSDLSEQLKQKHGEISFL 957


>U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein.
          Length = 1312

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 56/280 (20%), Positives = 129/280 (46%), Gaps = 28/280 (10%)

Query: 148 LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
           L+EV++  +S LR+A         +LK T++E    KKK K  ++++  + + +S   +K
Sbjct: 694 LQEVISDLQSKLRLA-------PDKLKSTESEL---KKKEKRRDEMLGLVPMRQSIIDLK 743

Query: 208 VKELREQAETAEQVAQ--SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXX 265
            KE+ E     + V +   R+       E L   +  +E+S  V                
Sbjct: 744 EKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELK 803

Query: 266 XQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR-- 323
              +    ++ +L  ++  R ++ V  ++ E   +   +  ++++ R  +   +E+++  
Sbjct: 804 DVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHL 863

Query: 324 -----QSRAEKDSFLNSLSRIAQ-GEGTESFQDKMAT---ELLDREQKIVKLQQTIDE-Q 373
                + ++EK     +L R  Q  E T     ++ +   E+ D ++++  L+ T+++ Q
Sbjct: 864 KSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQ 923

Query: 374 RENEKSMEQTMTQYENQLAALRL-EVK-RLRNYDCYSKDV 411
           +E E+ + +  T   N++A  +L ++K +++N   Y KD+
Sbjct: 924 QEKEELINKKNT--SNKIAQDKLNDIKEKVKNIHGYMKDI 961



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 29/144 (20%), Positives = 61/144 (42%), Gaps = 8/144 (5%)

Query: 78  EIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKK-ENEEPPCHPVQSGSYNYQVLNE 136
           + AK+  +D D  ++++ + ++E    QHK+D  S K E         Q    + +    
Sbjct: 812 QAAKLQGIDLDRTVQQVNQEKQEK---QHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTN 868

Query: 137 ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE----IAKKKHKDLEQ 192
           EL  E+       +     E         + +L R++KD K +        +K  ++ E+
Sbjct: 869 ELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEE 928

Query: 193 LVNRLAIERSHATVKVKELREQAE 216
           L+N+       A  K+ +++E+ +
Sbjct: 929 LINKKNTSNKIAQDKLNDIKEKVK 952


>BC104044-1|AAI04045.1|  830|Homo sapiens kinesin family member 7
           protein.
          Length = 830

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 71/299 (23%), Positives = 130/299 (43%), Gaps = 26/299 (8%)

Query: 132 QVLNEELSKERAAREALKEVVAS---AESMLRVARARIATLERQLKDTKAEFEIAKKKHK 188
           Q + E     R   E + E+V +   A+++ R    RI  LE++ +  +AE    +++ +
Sbjct: 195 QKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLR 254

Query: 189 DLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
           +LE    + A ERS    +++E R +   A+   Q  + E+K  TE L +  A+ EK   
Sbjct: 255 ELEGKELQDAGERS----RLQEFRRRVAAAQSQVQV-LKEKKQATERLVSLSAQSEK--- 306

Query: 249 VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                             Q Q    R +R  + E++R LE    K      +E E+ K  
Sbjct: 307 -----RLQELERNVQLMRQQQGQLQRRLR-EETEQKRRLEAEMSKRQHRV-KELEL-KHE 358

Query: 309 QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE-QKIVKLQ 367
           Q  +   +++EE     R  +     S+  + Q +  E  Q K     LD+E +K+++ +
Sbjct: 359 QQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEE-QKKW----LDQEMEKVLQQR 413

Query: 368 QTIDEQRENEKSMEQTMTQYENQL-AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
           + ++E  E     E  + + E  +     LE+KRLR+    ++D+     + E L+  L
Sbjct: 414 RALEELGEELHKREAILAKKEALMQEKTGLEIKRLRSSQALNEDIVRVSSRLEHLEKEL 472


>BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance of
           chromosomes 3 protein.
          Length = 1217

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 37/186 (19%), Positives = 83/186 (44%), Gaps = 4/186 (2%)

Query: 66  AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEE----PPC 121
           A++L+ ++  + E  K    +R  +++KIE  QKE +  + K +   +KE          
Sbjct: 309 AKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQA 368

Query: 122 HPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE 181
              ++  Y  Q    + + +    + +K+ + S +  +   + +IA + + L+DT+A  E
Sbjct: 369 TQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKE 428

Query: 182 IAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
              +++  L+Q +N +         K  E++ + +  +        E+ A  + L AK  
Sbjct: 429 KNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDELQSERNYLWREENAEQQALAAKRE 488

Query: 242 EQEKSK 247
           + EK +
Sbjct: 489 DLEKKQ 494


>AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance of
           chromosomes 3 protein.
          Length = 1217

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 37/186 (19%), Positives = 83/186 (44%), Gaps = 4/186 (2%)

Query: 66  AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEE----PPC 121
           A++L+ ++  + E  K    +R  +++KIE  QKE +  + K +   +KE          
Sbjct: 309 AKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQA 368

Query: 122 HPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE 181
              ++  Y  Q    + + +    + +K+ + S +  +   + +IA + + L+DT+A  E
Sbjct: 369 TQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKE 428

Query: 182 IAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
              +++  L+Q +N +         K  E++ + +  +        E+ A  + L AK  
Sbjct: 429 KNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDELQSERNYLWREENAEQQALAAKRE 488

Query: 242 EQEKSK 247
           + EK +
Sbjct: 489 DLEKKQ 494


>AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein
           protein.
          Length = 1173

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 56/280 (20%), Positives = 129/280 (46%), Gaps = 28/280 (10%)

Query: 148 LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
           L+EV++  +S LR+A         +LK T++E    KKK K  ++++  + + +S   +K
Sbjct: 555 LQEVISDLQSKLRLA-------PDKLKSTESEL---KKKEKRRDEMLGLVPMRQSIIDLK 604

Query: 208 VKELREQAETAEQVAQ--SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXX 265
            KE+ E     + V +   R+       E L   +  +E+S  V                
Sbjct: 605 EKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELK 664

Query: 266 XQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR-- 323
              +    ++ +L  ++  R ++ V  ++ E   +   +  ++++ R  +   +E+++  
Sbjct: 665 DVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHL 724

Query: 324 -----QSRAEKDSFLNSLSRIAQ-GEGTESFQDKMAT---ELLDREQKIVKLQQTIDE-Q 373
                + ++EK     +L R  Q  E T     ++ +   E+ D ++++  L+ T+++ Q
Sbjct: 725 KSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQ 784

Query: 374 RENEKSMEQTMTQYENQLAALRL-EVK-RLRNYDCYSKDV 411
           +E E+ + +  T   N++A  +L ++K +++N   Y KD+
Sbjct: 785 QEKEELINKKNT--SNKIAQDKLNDIKEKVKNIHGYMKDI 822



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 29/144 (20%), Positives = 61/144 (42%), Gaps = 8/144 (5%)

Query: 78  EIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKK-ENEEPPCHPVQSGSYNYQVLNE 136
           + AK+  +D D  ++++ + ++E    QHK+D  S K E         Q    + +    
Sbjct: 673 QAAKLQGIDLDRTVQQVNQEKQEK---QHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTN 729

Query: 137 ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE----IAKKKHKDLEQ 192
           EL  E+       +     E         + +L R++KD K +        +K  ++ E+
Sbjct: 730 ELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEE 789

Query: 193 LVNRLAIERSHATVKVKELREQAE 216
           L+N+       A  K+ +++E+ +
Sbjct: 790 LINKKNTSNKIAQDKLNDIKEKVK 813


>AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein.
          Length = 1312

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 56/280 (20%), Positives = 129/280 (46%), Gaps = 28/280 (10%)

Query: 148 LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
           L+EV++  +S LR+A         +LK T++E    KKK K  ++++  + + +S   +K
Sbjct: 694 LQEVISDLQSKLRLA-------PDKLKSTESEL---KKKEKRRDEMLGLVPMRQSIIDLK 743

Query: 208 VKELREQAETAEQVAQ--SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXX 265
            KE+ E     + V +   R+       E L   +  +E+S  V                
Sbjct: 744 EKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELK 803

Query: 266 XQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR-- 323
              +    ++ +L  ++  R ++ V  ++ E   +   +  ++++ R  +   +E+++  
Sbjct: 804 DVERKIAQQAAKLQGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHL 863

Query: 324 -----QSRAEKDSFLNSLSRIAQ-GEGTESFQDKMAT---ELLDREQKIVKLQQTIDE-Q 373
                + ++EK     +L R  Q  E T     ++ +   E+ D ++++  L+ T+++ Q
Sbjct: 864 KSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQ 923

Query: 374 RENEKSMEQTMTQYENQLAALRL-EVK-RLRNYDCYSKDV 411
           +E E+ + +  T   N++A  +L ++K +++N   Y KD+
Sbjct: 924 QEKEELINKKNT--SNKIAQDKLNDIKEKVKNIHGYMKDI 961



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 29/144 (20%), Positives = 61/144 (42%), Gaps = 8/144 (5%)

Query: 78  EIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKK-ENEEPPCHPVQSGSYNYQVLNE 136
           + AK+  +D D  ++++ + ++E    QHK+D  S K E         Q    + +    
Sbjct: 812 QAAKLQGIDLDRTVQQVNQEKQEK---QHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTN 868

Query: 137 ELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE----IAKKKHKDLEQ 192
           EL  E+       +     E         + +L R++KD K +        +K  ++ E+
Sbjct: 869 ELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEE 928

Query: 193 LVNRLAIERSHATVKVKELREQAE 216
           L+N+       A  K+ +++E+ +
Sbjct: 929 LINKKNTSNKIAQDKLNDIKEKVK 952


>AF020043-1|AAC14893.1| 1217|Homo sapiens chromosome-associated
           polypeptide protein.
          Length = 1217

 Score = 44.4 bits (100), Expect = 0.001
 Identities = 37/186 (19%), Positives = 83/186 (44%), Gaps = 4/186 (2%)

Query: 66  AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEE----PPC 121
           A++L+ ++  + E  K    +R  +++KIE  QKE +  + K +   +KE          
Sbjct: 309 AKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQA 368

Query: 122 HPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFE 181
              ++  Y  Q    + + +    + +K+ + S +  +   + +IA + + L+DT+A  E
Sbjct: 369 TQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEANKE 428

Query: 182 IAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVA 241
              +++  L+Q +N +         K  E++ + +  +        E+ A  + L AK  
Sbjct: 429 KNLEQYNKLDQDLNEVKARVEELDRKYYEVKNKKDELQSERNYLWREENAEQQALAAKRE 488

Query: 242 EQEKSK 247
           + EK +
Sbjct: 489 DLEKKQ 494


>X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein.
          Length = 1263

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 55/259 (21%), Positives = 106/259 (40%), Gaps = 10/259 (3%)

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           E L  +RA  +A  + +   +  L   +   + ++ Q  D +   + A+K+ K+  +   
Sbjct: 217 ETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKE 276

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           R   E +     ++      E AE+ A+S   E     E L+ +V E      +      
Sbjct: 277 RYMEEMADTADAIEMATLDKEMAEERAESLQQE----VEALKERVDELTTDLEILKAEIE 332

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIW-KELQMTRG 313
                      QL+   +++ RL D + R R L     +E+    +  E   +EL++ R 
Sbjct: 333 EKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ 392

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DE 372
              R +EEL Q+ +  D       ++    G E   + +    L+ E+K+ +L++T+ D 
Sbjct: 393 QRERLQEELSQAESTIDEL---KEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDL 449

Query: 373 QRENEKSMEQTMTQYENQL 391
           +  NE + E      E +L
Sbjct: 450 EAMNEMNDELQENARETEL 468



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 64/255 (25%), Positives = 114/255 (44%), Gaps = 31/255 (12%)

Query: 3   KNLIAQQNSLLEHYAILR--DMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTER-LH 59
           + L AQ   L E    LR    E +A +      ++++    EWK++  E   D +R L 
Sbjct: 203 EGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLK 262

Query: 60  RMVAGIAENLKAKINFSLEIA------KIPWLDRDTMIKKIERLQKENSILQHKVDETS- 112
                  E L+AK  +  E+A      ++  LD++   ++ E LQ+E   L+ +VDE + 
Sbjct: 263 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 322

Query: 113 -----KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIA 167
                K E EE       S SY  + L E+ ++ + A   +++ ++S+E    V      
Sbjct: 323 DLEILKAEIEEKGSDGAAS-SYQLKQLEEQNARLKDALVRMRD-LSSSEKQEHV------ 374

Query: 168 TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVS 227
            L++ ++    E E+ +++ + L++       E S A   + EL+EQ + A   A+  V 
Sbjct: 375 KLQKLMEKKNQELEVVRQQRERLQE-------ELSQAESTIDELKEQVDAA-LGAEEMVE 426

Query: 228 EQKARTEFLQAKVAE 242
               R   L+ KV E
Sbjct: 427 MLTDRNLNLEEKVRE 441



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 47/230 (20%), Positives = 101/230 (43%), Gaps = 7/230 (3%)

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ--SRVSEQK 230
           L     E E  + + +DLE+ +  L ++R+    K+KEL +     EQV +  S++ EQ+
Sbjct: 195 LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQ 254

Query: 231 ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYV 290
           A  +  + K A +E  +A+                 ++ +             ++ +E +
Sbjct: 255 ADLQ-RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEAL 313

Query: 291 PCKENEPTDRETEIWK-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQ 349
             + +E T  + EI K E++        S  +L+Q   +     ++L R+     +E  +
Sbjct: 314 KERVDELT-TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQE 372

Query: 350 DKMATELLDRE-QKIVKLQQTIDEQRENEKSMEQTMTQYENQL-AALRLE 397
                +L++++ Q++  ++Q  +  +E     E T+ + + Q+ AAL  E
Sbjct: 373 HVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAE 422



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 6/118 (5%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVARARI--ATLERQLKDTKAEFEI-AKKKHKDLE 191
           N+EL   R  RE L+E ++ AES +   + ++  A    ++ +   +  +  ++K ++L 
Sbjct: 384 NQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELR 443

Query: 192 QLVNRL-AIERSHATVKVKELREQAETAEQ--VAQSRVSEQKARTEFLQAKVAEQEKS 246
           + V  L A+   +  ++      + E  EQ  +A +RV E + R E  Q  VA+ +++
Sbjct: 444 ETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQT 501


>X06825-1|CAA29971.1|  284|Homo sapiens protein ( Human mRNA for
           skeletal beta-tropomyosin. ).
          Length = 284

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 49/242 (20%), Positives = 108/242 (44%), Gaps = 14/242 (5%)

Query: 170 ERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQ 229
           E + K  + E +  +KK K  E  V +     S +  + +E  EQAE     A++ V+  
Sbjct: 33  EDRCKQLEEEQQALQKKLKGTEDEVEKY----SESVKEAQEKLEQAEKKATDAEADVASL 88

Query: 230 KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
             R + ++ ++   ++  A A                 ++   +R+++  +    + ++ 
Sbjct: 89  NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQL 148

Query: 290 VPCKE-NEPTDRE-TEIWKELQMTRGALLRSEE--ELRQSRA-----EKDSFLNSLSRI- 339
              K   E +DR+  E+ ++L +  G L RSEE  E+ +S+      E     N+L  + 
Sbjct: 149 KEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLE 208

Query: 340 AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
           AQ +   + +DK   E+   E+K+ + +   +    +   +E+T+   E+++ A +++ K
Sbjct: 209 AQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYK 268

Query: 400 RL 401
            +
Sbjct: 269 AI 270



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 46/212 (21%), Positives = 93/212 (43%), Gaps = 12/212 (5%)

Query: 42  LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI-AKIPWLDRDTMI--KKIERLQ 98
           L+ K + TE  ++ E+    V    E L+     + +  A +  L+R   +  ++++R Q
Sbjct: 46  LQKKLKGTE--DEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103

Query: 99  KENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESM 158
           +  +    K++E  K  +E      V            EL +E   +EA K +   ++  
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEL-QEMQLKEA-KHIAEDSDRK 161

Query: 159 LRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ----LVNRLAIERSHATVKVKELREQ 214
                 ++  LE +L+ ++   E+A+ K  DLE+    + N L    + A  K     ++
Sbjct: 162 YEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQAD-KYSTKEDK 220

Query: 215 AETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
            E   ++ + ++ E + R EF +  VA+ EK+
Sbjct: 221 YEEEIKLLEEKLKEAETRAEFAERSVAKLEKT 252



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 32/143 (22%), Positives = 71/143 (49%), Gaps = 9/143 (6%)

Query: 293 KENEPTDRETEIWKE-LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK 351
           K+ + T+ E E + E ++  +  L ++E++   + A+  S LN   ++ + E  +  Q++
Sbjct: 48  KKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVAS-LNRRIQLVEEE-LDRAQER 105

Query: 352 MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
           +AT L    QK+ + ++  DE     K +E    + E ++    +++K  ++      D 
Sbjct: 106 LATAL----QKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHI-AEDSDR 160

Query: 412 SYPELQTEILDLHLQVETLSRER 434
            Y E+  +++ L  ++E  S ER
Sbjct: 161 KYEEVARKLVILEGELER-SEER 182


>M19715-1|AAA61227.1|  229|Homo sapiens TPM1 protein.
          Length = 229

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 42/218 (19%), Positives = 90/218 (41%), Gaps = 9/218 (4%)

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQ 229
           LKD + + E+A+KK  D E  V  L         ++   +E+  TA Q    A+    E 
Sbjct: 9   LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 68

Query: 230 KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
           +   + ++++  + E+   +                 + +    R + +++ +  R  E 
Sbjct: 69  ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVA-RKLVIIESDLERAEER 127

Query: 290 VPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLS-RIAQGEGTESF 348
               E +    E ++ + +  T  AL+ +E++  Q     +  +  LS ++ + E    F
Sbjct: 128 AELSEGQVRQLEEQL-RIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEF 186

Query: 349 QDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQ 386
            ++  T+L   E+ I  L++ +   +E   SM Q + Q
Sbjct: 187 AERSVTKL---EKSIDDLEEKVAHAKEENLSMHQMLDQ 221



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 29/159 (18%), Positives = 71/159 (44%), Gaps = 7/159 (4%)

Query: 92  KKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
           ++++R Q+  +    K++E  K  +E E     ++S +   Q   E++  +    +  K 
Sbjct: 42  EELDRAQERLATALQKLEEAEKAADESERGMKVIESRA---QKDEEKMEIQEIQLKEAKH 98

Query: 151 VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ---LVNRLAIERSHATVK 207
           +   A+        ++  +E  L+  +   E+++ + + LE+   ++++       A  K
Sbjct: 99  IAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDK 158

Query: 208 VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
             +  ++ E   +V   ++ E + R EF +  V + EKS
Sbjct: 159 YSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKS 197



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 38/166 (22%), Positives = 76/166 (45%), Gaps = 14/166 (8%)

Query: 307 ELQMTRGALLRSEE--ELRQSRA-EKDSFLNSLSRIAQ--GEGTESFQDKMATELLDREQ 361
           EL     AL  ++E  EL + +A + ++ + SL+R  Q   E  +  Q+++AT L    Q
Sbjct: 1   ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL----Q 56

Query: 362 KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEIL 421
           K+ + ++  DE     K +E    + E ++    +++K  ++      D  Y E+  +++
Sbjct: 57  KLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHI-AEDADRKYEEVARKLV 115

Query: 422 DLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKD 467
            +   +E  + ER  L   +  +   LE   R  D   + + A +D
Sbjct: 116 IIESDLER-AEERAEL---SEGQVRQLEEQLRIMDQTLKALMAAED 157


>DQ679757-1|ABG74698.1| 1215|Homo sapiens intersectin 1 short form
           variant 5 protein.
          Length = 1215

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short form
           variant 2 protein.
          Length = 1178

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 322 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 380

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 381 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 434

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 435 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 492

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 493 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 552

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 553 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 612

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 613 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 656


>DQ679755-1|ABG74696.1| 1149|Homo sapiens intersectin 1 short form
           variant 7 protein.
          Length = 1149

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>DQ679754-1|ABG74695.1| 1144|Homo sapiens intersectin 1 short form
           variant 6 protein.
          Length = 1144

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>DQ386455-1|ABD72328.1| 1020|Homo sapiens intersectin 1 short form
           transcript variant 8 protein.
          Length = 1020

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>DQ340865-1|ABC69037.1| 1076|Homo sapiens intersectin 1 short form
           protein.
          Length = 1076

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 357 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 415

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 416 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 469

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 470 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 527

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 528 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 587

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 588 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 647

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 648 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 691


>BX538175-1|CAD98050.1|  627|Homo sapiens hypothetical protein
           protein.
          Length = 627

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 214 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 272

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 273 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 326

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 327 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 384

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 385 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 444

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 445 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 504

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 505 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 548


>BX537985-1|CAD97945.1| 1202|Homo sapiens hypothetical protein
           protein.
          Length = 1202

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 65/344 (18%), Positives = 148/344 (43%), Gaps = 21/344 (6%)

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL-- 193
           ++L KE    + L++     ++ L     +I  LE++ K    E  I K+    L++L  
Sbjct: 7   KQLEKEN---KRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 63

Query: 194 VNRLAIERSHATVK-VKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
            N+  ++R+   +K +  LRE   + +   Q   ++ +  T  L+     +E+   +   
Sbjct: 64  ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER---LLHD 120

Query: 253 XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                         +L+S   +S+ + + E+   LE    +  E T+   ++ +EL+  +
Sbjct: 121 EQSTDDSRYKLLESKLESTLKKSLEIKE-EKIAALE---ARLEESTNYNQQLRQELKTVK 176

Query: 313 GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
               ++ E L+Q + E+    +S     +    E    +   ELL  + +++++++    
Sbjct: 177 ----KNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNAT 232

Query: 373 QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
            +  +++++  + Q E Q   L+ ++  L+     S       LQT+   L ++  TL+ 
Sbjct: 233 LQAEKQALKTQLKQLETQNNNLQTQILALQR-QTVSLQEQNTTLQTQNAKLQVENSTLNS 291

Query: 433 ERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRI 476
           + T+L+   A   +     E   +    +++ R+DL +L D  I
Sbjct: 292 QSTSLMNQNAQLLIQQSSLENENE---SVIKEREDLKSLYDSLI 332


>BX537964-1|CAD97928.1|  898|Homo sapiens hypothetical protein
           protein.
          Length = 898

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 74/404 (18%), Positives = 159/404 (39%), Gaps = 29/404 (7%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +++T+ KK+    KE     +K+ + S+++      +  + G     +   +  KE    
Sbjct: 328 EKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINS 387

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ-LVNRLAIERSHA 204
             +K  V  A++ L+         + +LK+T  +   AK++   + +   + +   +   
Sbjct: 388 HVIK--VKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESE 445

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            +K  EL  +    +   + ++ E+  + E   AK+ E E  K                 
Sbjct: 446 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRT----FKEGMDELRTL 501

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
             +++   D  +R  D E  +  E +  ++ E  +   ++ K     +  L R ++E+  
Sbjct: 502 RTKVKCLEDERLRTED-ELSKYKEIINRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIEN 559

Query: 325 SRAEKDSF---LNSLSRIAQGEGTES-----FQDKMATELLDREQKIVKLQQTIDEQREN 376
            + E +S    +N L +  +G          F +++ ++    + +   LQ   D+   +
Sbjct: 560 LKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCS 619

Query: 377 EKSME---QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
           E  ++   + M Q    L +  L+ + LR  +  +        QTE+  L  QVE L  E
Sbjct: 620 ESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDE 679

Query: 434 RTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRID 477
              L+T     A  ++      DL  ++ +AR+ L  +  G  D
Sbjct: 680 ---LVTQRRKHASSIK------DLTKQLQQARRKLDQVESGSYD 714



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 72/351 (20%), Positives = 135/351 (38%), Gaps = 35/351 (9%)

Query: 67  ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV---DETSKKENEEPPCHP 123
           +NL+ ++    E  K        +  +IE L KE    + ++   D T+K  N     H 
Sbjct: 231 DNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAK--NAVQQLH- 287

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  +   +  N++  + R  +EA+       E      R    TLE++L+D   E E  
Sbjct: 288 -KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKN 346

Query: 184 KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             K K L Q   RL     H   + KE     ET   + +    ++   +  ++ K A Q
Sbjct: 347 TNKIKQLSQEKGRL-----HQLYETKE----GETTRLIREIDKLKEDINSHVIKVKWA-Q 396

Query: 244 EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            K KA                    Q+  +      D  R+ C + +   +     +  E
Sbjct: 397 NKLKAEMDSHKETKDKLKETTTKLTQAKEE-----ADQIRKNCQDMIKTYQESEEIKSNE 451

Query: 304 IWKELQMTRGAL---LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK------MAT 354
           +  +L++T+G L   ++ + +  +    K   L  L R  + EG +  +        +  
Sbjct: 452 LDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFK-EGMDELRTLRTKVKCLED 510

Query: 355 ELLDREQKIVKLQQTIDEQR---ENEKSMEQTMTQYENQLAALRLEVKRLR 402
           E L  E ++ K ++ I+ Q+   +N     +T  Q + QL   + E++ L+
Sbjct: 511 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 561



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 70/318 (22%), Positives = 132/318 (41%), Gaps = 33/318 (10%)

Query: 95  ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
           ERL+ E+ + ++K     +K   +     V++       L E+L + +   E LKE V S
Sbjct: 511 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQ----LQEQLQRGKQEIENLKEEVES 566

Query: 155 AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             S++   +  I    ++  +     E    K+  L+   N L  +    +    +L+ Q
Sbjct: 567 LNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQ 626

Query: 215 AETAEQV---AQSRVSEQ----KARTEFLQAKVA-EQEKSKAVAXXXXXXXXXXXXXXXX 266
            E  +Q     +SR+ ++    K   + LQA++A  Q + KA++                
Sbjct: 627 CEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 686

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
              S +D + +L   + RR L+ V   E+   D+E         + G+L        +S 
Sbjct: 687 HASSIKDLTKQL--QQARRKLDQV---ESGSYDKEVSSMGSRSSSSGSL------NARSS 735

Query: 327 AEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQ 386
           AE  S  N+ S +A     ++F       L++R   IV+LQ+    + E  + ME  + Q
Sbjct: 736 AEDRSPENTGSSVA----VDNFPQVDKAMLIER---IVRLQKAHARKNEKIEFMEDHIKQ 788

Query: 387 YENQLAALRLEVKRLRNY 404
              +   +R + K +++Y
Sbjct: 789 LVEE---IRKKTKIIQSY 803


>BC117560-1|AAI17561.1| 1144|Homo sapiens ITSN1 protein protein.
          Length = 1144

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 domain
           protein) protein.
          Length = 1721

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein.
          Length = 1716

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>BC105632-1|AAI05633.1|  898|Homo sapiens chromosome 10 open reading
           frame 118 protein.
          Length = 898

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 74/404 (18%), Positives = 159/404 (39%), Gaps = 29/404 (7%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +++T+ KK+    KE     +K+ + S+++      +  + G     +   +  KE    
Sbjct: 328 EKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINS 387

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ-LVNRLAIERSHA 204
             +K  V  A++ L+         + +LK+T  +   AK++   + +   + +   +   
Sbjct: 388 HVIK--VKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESE 445

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            +K  EL  +    +   + ++ E+  + E   AK+ E E  K                 
Sbjct: 446 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRT----FKEGMDELRTL 501

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
             +++   D  +R  D E  +  E +  ++ E  +   ++ K     +  L R ++E+  
Sbjct: 502 RTKVKCLEDERLRTED-ELSKYKEIINRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIEN 559

Query: 325 SRAEKDSF---LNSLSRIAQGEGTES-----FQDKMATELLDREQKIVKLQQTIDEQREN 376
            + E +S    +N L +  +G          F +++ ++    + +   LQ   D+   +
Sbjct: 560 LKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCS 619

Query: 377 EKSME---QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
           E  ++   + M Q    L +  L+ + LR  +  +        QTE+  L  QVE L  E
Sbjct: 620 ESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDE 679

Query: 434 RTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRID 477
              L+T     A  ++      DL  ++ +AR+ L  +  G  D
Sbjct: 680 ---LVTQRRKHASSIK------DLTKQLQQARRKLDQVESGSYD 714



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 72/351 (20%), Positives = 135/351 (38%), Gaps = 35/351 (9%)

Query: 67  ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV---DETSKKENEEPPCHP 123
           +NL+ ++    E  K        +  +IE L KE    + ++   D T+K  N     H 
Sbjct: 231 DNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAK--NAVQQLH- 287

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  +   +  N++  + R  +EA+       E      R    TLE++L+D   E E  
Sbjct: 288 -KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKN 346

Query: 184 KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             K K L Q   RL     H   + KE     ET   + +    ++   +  ++ K A Q
Sbjct: 347 TNKIKQLSQEKGRL-----HQLYETKE----GETTRLIREIDKLKEDINSHVIKVKWA-Q 396

Query: 244 EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            K KA                    Q+  +      D  R+ C + +   +     +  E
Sbjct: 397 NKLKAEMDSHKETKDKLKETTTKLTQAKEE-----ADQIRKNCQDMIKTYQESEEIKSNE 451

Query: 304 IWKELQMTRGAL---LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK------MAT 354
           +  +L++T+G L   ++ + +  +    K   L  L R  + EG +  +        +  
Sbjct: 452 LDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFK-EGMDELRTLRTKVKCLED 510

Query: 355 ELLDREQKIVKLQQTIDEQR---ENEKSMEQTMTQYENQLAALRLEVKRLR 402
           E L  E ++ K ++ I+ Q+   +N     +T  Q + QL   + E++ L+
Sbjct: 511 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 561



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 70/318 (22%), Positives = 132/318 (41%), Gaps = 33/318 (10%)

Query: 95  ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
           ERL+ E+ + ++K     +K   +     V++       L E+L + +   E LKE V S
Sbjct: 511 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQ----LQEQLQRGKQEIENLKEEVES 566

Query: 155 AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             S++   +  I    ++  +     E    K+  L+   N L  +    +    +L+ Q
Sbjct: 567 LNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQ 626

Query: 215 AETAEQV---AQSRVSEQ----KARTEFLQAKVA-EQEKSKAVAXXXXXXXXXXXXXXXX 266
            E  +Q     +SR+ ++    K   + LQA++A  Q + KA++                
Sbjct: 627 CEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 686

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
              S +D + +L   + RR L+ V   E+   D+E         + G+L        +S 
Sbjct: 687 HASSIKDLTKQL--QQARRKLDQV---ESGSYDKEVSSMGSRSSSSGSL------NARSS 735

Query: 327 AEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQ 386
           AE  S  N+ S +A     ++F       L++R   IV+LQ+    + E  + ME  + Q
Sbjct: 736 AEDRSPENTGSSVA----VDNFPQVDKAMLIER---IVRLQKAHARKNEKIEFMEDHIKQ 788

Query: 387 YENQLAALRLEVKRLRNY 404
              +   +R + K +++Y
Sbjct: 789 LVEE---IRKKTKIIQSY 803


>BC103499-1|AAI03500.1|  898|Homo sapiens chromosome 10 open reading
           frame 118 protein.
          Length = 898

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 74/404 (18%), Positives = 159/404 (39%), Gaps = 29/404 (7%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +++T+ KK+    KE     +K+ + S+++      +  + G     +   +  KE    
Sbjct: 328 EKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINS 387

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ-LVNRLAIERSHA 204
             +K  V  A++ L+         + +LK+T  +   AK++   + +   + +   +   
Sbjct: 388 HVIK--VKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESE 445

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            +K  EL  +    +   + ++ E+  + E   AK+ E E  K                 
Sbjct: 446 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRT----FKEGMDELRTL 501

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
             +++   D  +R  D E  +  E +  ++ E  +   ++ K     +  L R ++E+  
Sbjct: 502 RTKVKCLEDERLRTED-ELSKYKEIINRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIEN 559

Query: 325 SRAEKDSF---LNSLSRIAQGEGTES-----FQDKMATELLDREQKIVKLQQTIDEQREN 376
            + E +S    +N L +  +G          F +++ ++    + +   LQ   D+   +
Sbjct: 560 LKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCS 619

Query: 377 EKSME---QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
           E  ++   + M Q    L +  L+ + LR  +  +        QTE+  L  QVE L  E
Sbjct: 620 ESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDE 679

Query: 434 RTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRID 477
              L+T     A  ++      DL  ++ +AR+ L  +  G  D
Sbjct: 680 ---LVTQRRKHASSIK------DLTKQLQQARRKLDQVESGSYD 714



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 73/351 (20%), Positives = 135/351 (38%), Gaps = 35/351 (9%)

Query: 67  ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV---DETSKKENEEPPCHP 123
           +NL+ ++    E  K        +  +IE L KE    + K+   D T+K  N     H 
Sbjct: 231 DNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDKLIAQDVTAK--NAVQQLH- 287

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  +   +  N++  + R  +EA+       E      R    TLE++L+D   E E  
Sbjct: 288 -KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKN 346

Query: 184 KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             K K L Q   RL     H   + KE     ET   + +    ++   +  ++ K A Q
Sbjct: 347 TNKIKQLSQEKGRL-----HQLYETKE----GETTRLIREIDKLKEDINSHVIKVKWA-Q 396

Query: 244 EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            K KA                    Q+  +      D  R+ C + +   +     +  E
Sbjct: 397 NKLKAEMDSHKETKDKLKETTTKLTQAKEE-----ADQIRKNCQDMIKTYQESEEIKSNE 451

Query: 304 IWKELQMTRGAL---LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK------MAT 354
           +  +L++T+G L   ++ + +  +    K   L  L R  + EG +  +        +  
Sbjct: 452 LDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFK-EGMDELRTLRTKVKCLED 510

Query: 355 ELLDREQKIVKLQQTIDEQR---ENEKSMEQTMTQYENQLAALRLEVKRLR 402
           E L  E ++ K ++ I+ Q+   +N     +T  Q + QL   + E++ L+
Sbjct: 511 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 561



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 70/318 (22%), Positives = 132/318 (41%), Gaps = 33/318 (10%)

Query: 95  ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
           ERL+ E+ + ++K     +K   +     V++       L E+L + +   E LKE V S
Sbjct: 511 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQ----LQEQLQRGKQEIENLKEEVES 566

Query: 155 AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             S++   +  I    ++  +     E    K+  L+   N L  +    +    +L+ Q
Sbjct: 567 LNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQ 626

Query: 215 AETAEQV---AQSRVSEQ----KARTEFLQAKVA-EQEKSKAVAXXXXXXXXXXXXXXXX 266
            E  +Q     +SR+ ++    K   + LQA++A  Q + KA++                
Sbjct: 627 CEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 686

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
              S +D + +L   + RR L+ V   E+   D+E         + G+L        +S 
Sbjct: 687 HASSIKDLTKQL--QQARRKLDQV---ESGSYDKEVSSMGSRSSSSGSL------NARSS 735

Query: 327 AEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQ 386
           AE  S  N+ S +A     ++F       L++R   IV+LQ+    + E  + ME  + Q
Sbjct: 736 AEDRSPENTGSSVA----VDNFPQVDKAMLIER---IVRLQKAHARKNEKIEFMEDHIKQ 788

Query: 387 YENQLAALRLEVKRLRNY 404
              +   +R + K +++Y
Sbjct: 789 LVEE---IRKKTKIIQSY 803


>BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.
          Length = 1004

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 74/404 (18%), Positives = 159/404 (39%), Gaps = 29/404 (7%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +++T+ KK+    KE     +K+ + S+++      +  + G     +   +  KE    
Sbjct: 434 EKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINS 493

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ-LVNRLAIERSHA 204
             +K  V  A++ L+         + +LK+T  +   AK++   + +   + +   +   
Sbjct: 494 HVIK--VKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESE 551

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            +K  EL  +    +   + ++ E+  + E   AK+ E E  K                 
Sbjct: 552 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRT----FKEGMDELRTL 607

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
             +++   D  +R  D E  +  E +  ++ E  +   ++ K     +  L R ++E+  
Sbjct: 608 RTKVKCLEDERLRTED-ELSKYKEIINRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIEN 665

Query: 325 SRAEKDSF---LNSLSRIAQGEGTES-----FQDKMATELLDREQKIVKLQQTIDEQREN 376
            + E +S    +N L +  +G          F +++ ++    + +   LQ   D+   +
Sbjct: 666 LKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCS 725

Query: 377 EKSME---QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
           E  ++   + M Q    L +  L+ + LR  +  +        QTE+  L  QVE L  E
Sbjct: 726 ESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDE 785

Query: 434 RTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRID 477
              L+T     A  ++      DL  ++ +AR+ L  +  G  D
Sbjct: 786 ---LVTQRRKHASSIK------DLTKQLQQARRKLDQVESGSYD 820



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 72/351 (20%), Positives = 135/351 (38%), Gaps = 35/351 (9%)

Query: 67  ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV---DETSKKENEEPPCHP 123
           +NL+ ++    E  K        +  +IE L KE    + ++   D T+K  N     H 
Sbjct: 337 DNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAK--NAVQQLH- 393

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  +   +  N++  + R  +EA+       E      R    TLE++L+D   E E  
Sbjct: 394 -KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKN 452

Query: 184 KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             K K L Q   RL     H   + KE     ET   + +    ++   +  ++ K A Q
Sbjct: 453 TNKIKQLSQEKGRL-----HQLYETKE----GETTRLIREIDKLKEDINSHVIKVKWA-Q 502

Query: 244 EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            K KA                    Q+  +      D  R+ C + +   +     +  E
Sbjct: 503 NKLKAEMDSHKETKDKLKETTTKLTQAKEE-----ADQIRKNCQDMIKTYQESEEIKSNE 557

Query: 304 IWKELQMTRGAL---LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK------MAT 354
           +  +L++T+G L   ++ + +  +    K   L  L R  + EG +  +        +  
Sbjct: 558 LDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFK-EGMDELRTLRTKVKCLED 616

Query: 355 ELLDREQKIVKLQQTIDEQR---ENEKSMEQTMTQYENQLAALRLEVKRLR 402
           E L  E ++ K ++ I+ Q+   +N     +T  Q + QL   + E++ L+
Sbjct: 617 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 667



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 70/318 (22%), Positives = 132/318 (41%), Gaps = 33/318 (10%)

Query: 95  ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
           ERL+ E+ + ++K     +K   +     V++       L E+L + +   E LKE V S
Sbjct: 617 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQ----LQEQLQRGKQEIENLKEEVES 672

Query: 155 AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             S++   +  I    ++  +     E    K+  L+   N L  +    +    +L+ Q
Sbjct: 673 LNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQ 732

Query: 215 AETAEQV---AQSRVSEQ----KARTEFLQAKVA-EQEKSKAVAXXXXXXXXXXXXXXXX 266
            E  +Q     +SR+ ++    K   + LQA++A  Q + KA++                
Sbjct: 733 CEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 792

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
              S +D + +L   + RR L+ V   E+   D+E         + G+L        +S 
Sbjct: 793 HASSIKDLTKQL--QQARRKLDQV---ESGSYDKEVSSMGSRSSSSGSL------NARSS 841

Query: 327 AEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQ 386
           AE  S  N+ S +A     ++F       L++R   IV+LQ+    + E  + ME  + Q
Sbjct: 842 AEDRSPENTGSSVA----VDNFPQVDKAMLIER---IVRLQKAHARKNEKIEFMEDHIKQ 894

Query: 387 YENQLAALRLEVKRLRNY 404
              +   +R + K +++Y
Sbjct: 895 LVEE---IRKKTKIIQSY 909


>BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein.
          Length = 1139

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 55/259 (21%), Positives = 106/259 (40%), Gaps = 10/259 (3%)

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           E L  +RA  +A  + +   +  L   +   + ++ Q  D +   + A+K+ K+  +   
Sbjct: 98  ETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKE 157

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           R   E +     ++      E AE+ A+S   E     E L+ +V E      +      
Sbjct: 158 RYMEEMADTADAIEMATLDKEMAEERAESLQQE----VEALKERVDELTTDLEILKAEIE 213

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIW-KELQMTRG 313
                      QL+   +++ RL D + R R L     +E+    +  E   +EL++ R 
Sbjct: 214 EKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ 273

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DE 372
              R +EEL Q+ +  D       ++    G E   + +    L+ E+K+ +L++T+ D 
Sbjct: 274 QRERLQEELSQAESTIDEL---KEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDL 330

Query: 373 QRENEKSMEQTMTQYENQL 391
           +  NE + E      E +L
Sbjct: 331 EAMNEMNDELQENARETEL 349



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 64/255 (25%), Positives = 114/255 (44%), Gaps = 31/255 (12%)

Query: 3   KNLIAQQNSLLEHYAILR--DMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTER-LH 59
           + L AQ   L E    LR    E +A +      ++++    EWK++  E   D +R L 
Sbjct: 84  EGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLK 143

Query: 60  RMVAGIAENLKAKINFSLEIA------KIPWLDRDTMIKKIERLQKENSILQHKVDETS- 112
                  E L+AK  +  E+A      ++  LD++   ++ E LQ+E   L+ +VDE + 
Sbjct: 144 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 203

Query: 113 -----KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIA 167
                K E EE       S SY  + L E+ ++ + A   +++ ++S+E    V      
Sbjct: 204 DLEILKAEIEEKGSDGAAS-SYQLKQLEEQNARLKDALVRMRD-LSSSEKQEHV------ 255

Query: 168 TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVS 227
            L++ ++    E E+ +++ + L++       E S A   + EL+EQ + A   A+  V 
Sbjct: 256 KLQKLMEKKNQELEVVRQQRERLQE-------ELSQAESTIDELKEQVDAA-LGAEEMVE 307

Query: 228 EQKARTEFLQAKVAE 242
               R   L+ KV E
Sbjct: 308 MLTDRNLNLEEKVRE 322



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 47/230 (20%), Positives = 101/230 (43%), Gaps = 7/230 (3%)

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ--SRVSEQK 230
           L     E E  + + +DLE+ +  L ++R+    K+KEL +     EQV +  S++ EQ+
Sbjct: 76  LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQ 135

Query: 231 ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYV 290
           A  +  + K A +E  +A+                 ++ +             ++ +E +
Sbjct: 136 ADLQ-RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEAL 194

Query: 291 PCKENEPTDRETEIWK-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQ 349
             + +E T  + EI K E++        S  +L+Q   +     ++L R+     +E  +
Sbjct: 195 KERVDELT-TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQE 253

Query: 350 DKMATELLDRE-QKIVKLQQTIDEQRENEKSMEQTMTQYENQL-AALRLE 397
                +L++++ Q++  ++Q  +  +E     E T+ + + Q+ AAL  E
Sbjct: 254 HVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAE 303



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 6/118 (5%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVARARI--ATLERQLKDTKAEFEI-AKKKHKDLE 191
           N+EL   R  RE L+E ++ AES +   + ++  A    ++ +   +  +  ++K ++L 
Sbjct: 265 NQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELR 324

Query: 192 QLVNRL-AIERSHATVKVKELREQAETAEQ--VAQSRVSEQKARTEFLQAKVAEQEKS 246
           + V  L A+   +  ++      + E  EQ  +A +RV E + R E  Q  VA+ +++
Sbjct: 325 ETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQT 382


>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
           MU-RMS-40.7B protein.
          Length = 1179

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 66/359 (18%), Positives = 150/359 (41%), Gaps = 22/359 (6%)

Query: 87  RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA-R 145
           R+   +K+ R   E + LQH+    + ++        +     N Q + ++L KE++  +
Sbjct: 411 REAEFQKMRR-DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 469

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
             L +V ++ E +++ A+A +  + R L+D   E    + K ++ ++ VN L  +++   
Sbjct: 470 LELDDVTSNMEQIIK-AKANLEKMCRTLEDQMNEH---RSKAEETQRSVNDLTSQQAKLQ 525

Query: 206 VKVKELREQAETAE----QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
            +  EL  Q +  E    Q+ + +++  + + E L+ ++ E+ K+K              
Sbjct: 526 TENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQLEEEVKAKNALAHALQSARHDC 584

Query: 262 XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD--RETEIWKELQMTRGALLRSE 319
                Q +   +    L  +  +   E    +    TD  + TE  +E +      L+  
Sbjct: 585 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 644

Query: 320 EELRQSRAEKDSFLNSLSRIAQGEGTESFQD----KMATELLDREQKIVKLQQTIDEQRE 375
           EE  ++   K S L       Q E  +   D      A   LD++Q+     + + E ++
Sbjct: 645 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR--NFDKILAEWKQ 702

Query: 376 NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE-LQTEILDLHLQVETLSRE 433
             +  +  +   + +  +L  E+ +L+N   Y + + + E  + E  +L  ++  L+ +
Sbjct: 703 KYEESQSELESSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEISDLTEQ 759



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 70/340 (20%), Positives = 137/340 (40%), Gaps = 24/340 (7%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           L   L +E+  R  L+      E  L++ +  I  LE    D +   E  KKK  +L  L
Sbjct: 278 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN---DKQQLDERLKKKDFELNAL 334

Query: 194 VNRLAIER---SHATVKVKELREQAETAEQVAQ----SRVSEQKARTEFLQAKVAEQEKS 246
             R+  E+   S    K+KEL+ + E  E+  +    +R   +K R++ L  ++ E  + 
Sbjct: 335 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSD-LSRELEEISER 393

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK 306
              A                + Q  R R +    ++       +  K     D   E+ +
Sbjct: 394 LEEAGGATSVQIEMNKKREAEFQKMR-RDLEEATLQHEATAAALRKKH---ADSVAELGE 449

Query: 307 ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDR-EQKIVK 365
           ++   +    + E+E  + + E D   +++ +I + +      +KM   L D+  +   K
Sbjct: 450 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN---LEKMCRTLEDQMNEHRSK 506

Query: 366 LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
            ++T  ++  N+ + +Q   Q EN   + +L+ K           ++Y + Q E L   L
Sbjct: 507 AEET--QRSVNDLTSQQAKLQTENGELSRQLDEKEALISQLTRGKLTYTQ-QLEDLKRQL 563

Query: 426 QVETLSRERT--ALITAAASRALMLERHERAADLFARMVR 463
           + E  ++     AL +A     L+ E++E   +  A + R
Sbjct: 564 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 603



 Score = 37.9 bits (84), Expect = 0.080
 Identities = 26/111 (23%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query: 135 NEELSKERAAREALKEV---VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
           NE L  ++     L E+   ++ A  M   A+ ++ +L+  LKDT+ + + A + + DL+
Sbjct: 853 NEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK 912

Query: 192 QLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQAK 239
           + +  +    +    +++ELR   EQ E + ++A+  + E   R + L ++
Sbjct: 913 ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 963



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 68/373 (18%), Positives = 154/373 (41%), Gaps = 28/373 (7%)

Query: 66  AENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQ 125
           AE  K   +   E  ++      +  ++ E  +K  S+LQ K D   + + E+      +
Sbjct: 87  AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 146

Query: 126 SGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKK 185
                 Q++  ++  E   +E + E +   E M     A +   +R+L+D  +E    K+
Sbjct: 147 ERCD--QLIKNKIQLEAKVKE-MNERLEDEEEM----NAELTAKKRKLEDECSEL---KR 196

Query: 186 KHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAE-QE 244
              DLE  + ++  E+     KVK L E+    +++      E+KA  E  Q  + + Q 
Sbjct: 197 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQA 256

Query: 245 KSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEI 304
           +   V                 +    +++ +R+ D+ER +             + + ++
Sbjct: 257 EEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM-DLERAK----------RKLEGDLKL 305

Query: 305 WKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIV 364
            +E  M    L   +++L +   +KD  LN+L+  A+ E  ++   ++  +L + + +I 
Sbjct: 306 TQESIMD---LENDKQQLDERLKKKDFELNALN--ARIEDEQALGSQLQKKLKELQARIE 360

Query: 365 KLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYP-ELQTEILDL 423
           +L++ ++ +R     +E+  +    +L  +   ++          +++   E + + +  
Sbjct: 361 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 420

Query: 424 HLQVETLSRERTA 436
            L+  TL  E TA
Sbjct: 421 DLEEATLQHEATA 433



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 69/353 (19%), Positives = 140/353 (39%), Gaps = 36/353 (10%)

Query: 132 QVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLE 191
           ++  E+ + + A ++AL ++ A  + +  + +A++  LE+Q+ D +   E  KK   DLE
Sbjct: 235 KLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK-LEQQVDDLEGSLEQEKKVRMDLE 293

Query: 192 QLVNRLAIERSHATVKVKELREQAETAEQ----------VAQSRVSEQKARTEFLQAKVA 241
           +   +L  +       + +L    +  ++             +R+ +++A    LQ K+ 
Sbjct: 294 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 353

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
           E + ++                   +L+S   R +  +             +      RE
Sbjct: 354 ELQ-ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 412

Query: 302 TEIWKELQMTRGALLRSE---EELRQ----SRAEKDSFLNSLSRIAQGEGTESFQDKM-A 353
            E  K  +    A L+ E     LR+    S AE    +++L R+ Q    E  + K+  
Sbjct: 413 AEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEL 472

Query: 354 TELLDREQKIVK-----------LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL- 401
            ++    ++I+K           L+  ++E R   +  ++++    +Q A L+ E   L 
Sbjct: 473 DDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAKLQTENGELS 532

Query: 402 RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA--AASRALMLERHE 452
           R  D   K+    +L    L    Q+E L R+    + A  A + AL   RH+
Sbjct: 533 RQLD--EKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHD 583



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 71/330 (21%), Positives = 130/330 (39%), Gaps = 38/330 (11%)

Query: 89   TMIKKIERLQKENSILQHKVDETSKKEN----EEPPCHPVQSGSYNYQVLNEELSKERAA 144
            T + K++   +E+  L+H   ET K+EN    EE      Q GS    +   EL K R  
Sbjct: 723  TELFKLKNAYEES--LEHL--ETFKRENKNLQEEISDLTEQLGSSGKTI--HELEKVRKQ 776

Query: 145  REA----LKEVVASAESMLRVARARIATLERQLKDTKAEFEIA-KKKHKDLEQLV-NRLA 198
             EA    L+  +  AE+ L     +I   + +    KAE E    +K +++EQ   N L 
Sbjct: 777  LEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 836

Query: 199  IERSHATVKVKELREQAET--AEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXX 256
            +  S  T    E R + E    ++  +  ++E + +        AE +K           
Sbjct: 837  VVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ---VKSLQSL 893

Query: 257  XXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALL 316
                       +++  D    +  +ERR  L     +E      +TE  +  ++    L+
Sbjct: 894  LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTE--RSRKLAEQELI 951

Query: 317  RSEEELRQSRAEKDSFLNSLSRI------AQGEGTESFQD---------KMATELLDREQ 361
             + E ++   ++  S +N   ++       Q E  E+ Q+         K  T+     +
Sbjct: 952  ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAE 1011

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
            ++ K Q T       +K+MEQT+   +++L
Sbjct: 1012 ELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1041



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 51/208 (24%), Positives = 97/208 (46%), Gaps = 32/208 (15%)

Query: 49   TEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK--ENSI--L 104
            ++   + E   +      E  K  I  +  +A+    ++DT    +ER++K  E +I  L
Sbjct: 979  SQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNMEQTIKDL 1037

Query: 105  QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            QH++DE  +          ++ G    Q L   + +     EA  E   +AES+  + ++
Sbjct: 1038 QHRLDEAEQIA--------LKGGKKQLQKLEARVRELENELEA--EQKRNAESVKGMRKS 1087

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
                 ER++K+   + E  +K    L+ LV++L +       KVK  + QAE AE+ A +
Sbjct: 1088 -----ERRIKELTYQTEEDRKNLLRLQDLVDKLQL-------KVKAYKRQAEEAEEQANT 1135

Query: 225  RVSE-QKARTEFLQAK----VAEQEKSK 247
             +S+ +K + E  +A+    +AE + +K
Sbjct: 1136 NLSKFRKVQHELDEAEERADIAESQVNK 1163


>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
            protein.
          Length = 1331

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 85/393 (21%), Positives = 162/393 (41%), Gaps = 48/393 (12%)

Query: 109  DETSKKENEEPPCHPVQSGS----YNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
            D  ++ E EE  C  +Q+       N Q L E+L +E +AR+ L+    + E+ L+    
Sbjct: 783  DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 842

Query: 165  RIATLERQLKDTKAEFEIAKKKHKDLEQLV-------NRLAIERSHATVKVKELREQA-- 215
             +  L   L   +      +KK K  +QL+        + A ER  A  + +E   +A  
Sbjct: 843  ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGERDRAEAEAREKETKALS 902

Query: 216  ------ETAEQVAQSRVSEQKARTE---FLQAK------VAEQEKSKAVAXXXXXXXXXX 260
                  E  EQ A+     ++ RTE    + +K      V E EKSK             
Sbjct: 903  LARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQ 962

Query: 261  XXXXXXQLQSFRDRSIRL-VDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE 319
                  +LQ+  D  +RL V+++  +  ++   ++ +  D ++E  K+ Q+ R  +   E
Sbjct: 963  LEELEGELQATEDAKLRLEVNLQAMKA-QFE--RDLQGRDEQSE-EKKKQLVR-QVREME 1017

Query: 320  EELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKS 379
             EL   R ++   + +  ++      +  +  + +   +R++ I +L++   + ++  + 
Sbjct: 1018 AELEDERKQRSMAVAARKKLEM--DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1075

Query: 380  MEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALIT 439
            ++ T    E  LA  +   K+L+     S +    +LQ E+           +ER  L  
Sbjct: 1076 LDDTRASREEILAQAKENEKKLK-----SMEAEMIQLQEELAAAERAKRQAQQERDELAD 1130

Query: 440  AAASR----ALMLERHERAADLFARMVRARKDL 468
              A+     AL LE   R   L AR+ +  ++L
Sbjct: 1131 EIANSSGKGALALEEKRR---LEARIAQLEEEL 1160



 Score = 43.2 bits (97), Expect = 0.002
 Identities = 61/234 (26%), Positives = 105/234 (44%), Gaps = 35/234 (14%)

Query: 45   KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLD--RDTMIKKIERLQKENS 102
            + R  E + + ER  R +A +A   K +++     A I   +  RD  IK++ +LQ +  
Sbjct: 1012 QVREMEAELEDERKQRSMA-VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1070

Query: 103  ILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEELSK-ERAAREALKEVVASAE 156
                ++D+T     E     +     ++S       L EEL+  ERA R+A +E    A+
Sbjct: 1071 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1130

Query: 157  SML-------------RVARARIATLERQLKDTKAEFEIA----KKKHKDLEQLVNRLAI 199
             +              R   ARIA LE +L++ +   E+     KK +  ++Q+   L +
Sbjct: 1131 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1190

Query: 200  ERSHATVKVKELREQAETAEQVAQSRVSEQ--------KARTEFLQAKVAEQEK 245
            ERSHA  K +  R+Q E   +  + ++ E         KA    L+AK+A+ E+
Sbjct: 1191 ERSHAQ-KNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1243



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 72/345 (20%), Positives = 141/345 (40%), Gaps = 18/345 (5%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EEL K R  + A +  +   E++     A    L+ QL+   AE E+      + E+L  
Sbjct: 716  EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ---AETELCA----EAEELRA 768

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            RL  ++        +L  + E  E+  Q   +E+K   + +Q ++ EQ + +  A     
Sbjct: 769  RLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ-ELEEQLEEEESARQKLQ 827

Query: 256  XXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMT-RGA 314
                       +L+   D    LVD++ +R       K+ +  D+     K +     G 
Sbjct: 828  LEKVTTEAKLKKLEEELDD--LLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGE 885

Query: 315  LLRSEEELRQSRAEKDSFLNSLSR-IAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
              R+E E R+   +  S   +L   + Q    E    +  TE+ D       + +++ E 
Sbjct: 886  RDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 945

Query: 374  RENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEI-LDLHLQVETLSR 432
             ++++++EQ + + + QL  L  E++   +      +V+   ++ +   DL  + E    
Sbjct: 946  EKSKRALEQQVEEMKTQLEELEGELQATEDAK-LRLEVNLQAMKAQFERDLQGRDEQSEE 1004

Query: 433  ERTALITAAASRALML--ERHERAADLFAR--MVRARKDLAALLD 473
            ++  L+         L  ER +R+  + AR  +    KDL A +D
Sbjct: 1005 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1049


>AL133410-4|CAI10977.1|  284|Homo sapiens tropomyosin 2 (beta)
           protein.
          Length = 284

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 49/242 (20%), Positives = 108/242 (44%), Gaps = 14/242 (5%)

Query: 170 ERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQ 229
           E + K  + E +  +KK K  E  V +     S +  + +E  EQAE     A++ V+  
Sbjct: 33  EDRCKQLEEEQQALQKKLKGTEDEVEKY----SESVKEAQEKLEQAEKKATDAEADVASL 88

Query: 230 KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
             R + ++ ++   ++  A A                 ++   +R+++  +    + ++ 
Sbjct: 89  NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQL 148

Query: 290 VPCKE-NEPTDRE-TEIWKELQMTRGALLRSEE--ELRQSRA-----EKDSFLNSLSRI- 339
              K   E +DR+  E+ ++L +  G L RSEE  E+ +S+      E     N+L  + 
Sbjct: 149 KEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLE 208

Query: 340 AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVK 399
           AQ +   + +DK   E+   E+K+ + +   +    +   +E+T+   E+++ A +++ K
Sbjct: 209 AQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYK 268

Query: 400 RL 401
            +
Sbjct: 269 AI 270



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 46/212 (21%), Positives = 93/212 (43%), Gaps = 12/212 (5%)

Query: 42  LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI-AKIPWLDRDTMI--KKIERLQ 98
           L+ K + TE  ++ E+    V    E L+     + +  A +  L+R   +  ++++R Q
Sbjct: 46  LQKKLKGTE--DEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQ 103

Query: 99  KENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESM 158
           +  +    K++E  K  +E      V            EL +E   +EA K +   ++  
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEL-QEMQLKEA-KHIAEDSDRK 161

Query: 159 LRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ----LVNRLAIERSHATVKVKELREQ 214
                 ++  LE +L+ ++   E+A+ K  DLE+    + N L    + A  K     ++
Sbjct: 162 YEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQAD-KYSTKEDK 220

Query: 215 AETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
            E   ++ + ++ E + R EF +  VA+ EK+
Sbjct: 221 YEEEIKLLEEKLKEAETRAEFAERSVAKLEKT 252



 Score = 31.9 bits (69), Expect = 5.3
 Identities = 32/143 (22%), Positives = 71/143 (49%), Gaps = 9/143 (6%)

Query: 293 KENEPTDRETEIWKE-LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK 351
           K+ + T+ E E + E ++  +  L ++E++   + A+  S LN   ++ + E  +  Q++
Sbjct: 48  KKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVAS-LNRRIQLVEEE-LDRAQER 105

Query: 352 MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
           +AT L    QK+ + ++  DE     K +E    + E ++    +++K  ++      D 
Sbjct: 106 LATAL----QKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHI-AEDSDR 160

Query: 412 SYPELQTEILDLHLQVETLSRER 434
            Y E+  +++ L  ++E  S ER
Sbjct: 161 KYEEVARKLVILEGELER-SEER 182


>AK024959-1|BAB15043.1|  696|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ21306 fis, clone COL02125. ).
          Length = 696

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 39/168 (23%), Positives = 81/168 (48%), Gaps = 10/168 (5%)

Query: 85  LDRDTMIKKIERLQKE------NSILQHK---VDETSKKENEEPPCHPVQSGSYNYQVLN 135
           L+++++I K+ER  KE      +S+   K   V E   KE      + +Q   +  Q+  
Sbjct: 399 LEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKE 458

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           EE    R   E LKE ++++ +  +  +A +   E    D K +   AKK+ K +++ V+
Sbjct: 459 EEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVS 518

Query: 196 RLAIERSHATVKVKEL-REQAETAEQVAQSRVSEQKARTEFLQAKVAE 242
            +  E     +K+ EL +++ + ++++   + + Q+ + +    KV E
Sbjct: 519 VMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEE 566



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 54/307 (17%), Positives = 123/307 (40%), Gaps = 9/307 (2%)

Query: 86  DRDTMIKKI-ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           +++T+I+++ E LQ++N  L  ++    + +        +  G   Y+   +EL      
Sbjct: 327 EKETLIQQLKEELQEKNVTLDVQIQHVVEGKRA---LSELTQGVTCYKAKIKELETILET 383

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
           ++  +   A  E  +    + I  LER LK+ +   + + K  KDL     +L  E +  
Sbjct: 384 QKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQL 443

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
           T  +++++   +  E+  ++   E +   E L A  A  +  KA                
Sbjct: 444 TNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKL 503

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
               +  +     +  M     L  +  K NE   ++ +  +EL M +  + + +E+L  
Sbjct: 504 TDAKKQIKQVQKEVSVMRDEDKL--LRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNN 561

Query: 325 SRAEKDSFLNSLSRIAQGEGT-ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
            + E+   +    R  +     E   + M   L ++EQ  V+  Q ++ + E  + +   
Sbjct: 562 QKVEE--AIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATE 619

Query: 384 MTQYENQ 390
           + +++ +
Sbjct: 620 LEKWKEK 626


>AF273054-1|AAM44457.1|  613|Homo sapiens CTCL tumor antigen
           HD-CL-01 protein.
          Length = 613

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 74/404 (18%), Positives = 159/404 (39%), Gaps = 29/404 (7%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
           +++T+ KK+    KE     +K+ + S+++      +  + G     +   +  KE    
Sbjct: 145 EKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINS 204

Query: 146 EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ-LVNRLAIERSHA 204
             +K  V  A++ L+         + +LK+T  +   AK++   + +   + +   +   
Sbjct: 205 HVIK--VKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESE 262

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            +K  EL  +    +   + ++ E+  + E   AK+ E E  K                 
Sbjct: 263 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRT----FKEGMDELRTL 318

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
             +++   D  +R  D E  +  E +  ++ E  +   ++ K     +  L R ++E+  
Sbjct: 319 RTKVKCLEDERLRTED-ELSKYKEIINRQKAEIQNLLDKV-KTADQLQEQLQRGKQEIEN 376

Query: 325 SRAEKDSF---LNSLSRIAQGEGTES-----FQDKMATELLDREQKIVKLQQTIDEQREN 376
            + E +S    +N L +  +G          F +++ ++    + +   LQ   D+   +
Sbjct: 377 LKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCS 436

Query: 377 EKSME---QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
           E  ++   + M Q    L +  L+ + LR  +  +        QTE+  L  QVE L  E
Sbjct: 437 ESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDE 496

Query: 434 RTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRID 477
              L+T     A  ++      DL  ++ +AR+ L  +  G  D
Sbjct: 497 ---LVTQRRKHASSIK------DLTKQLQQARRKLDQVESGSYD 531



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 73/351 (20%), Positives = 135/351 (38%), Gaps = 35/351 (9%)

Query: 67  ENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKV---DETSKKENEEPPCHP 123
           +NL+ ++    E  K        +  +IE L KE    + K+   D T+K  N     H 
Sbjct: 48  DNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDKLIAQDVTAK--NAVQQLH- 104

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            +  +   +  N++  + R  +EA+       E      R    TLE++L+D   E E  
Sbjct: 105 -KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKN 163

Query: 184 KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
             K K L Q   RL     H   + KE     ET   + +    ++   +  ++ K A Q
Sbjct: 164 TNKIKQLSQEKGRL-----HQLYETKE----GETTRLIREIDKLKEDINSHVIKVKWA-Q 213

Query: 244 EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETE 303
            K KA                    Q+  +      D  R+ C + +   +     +  E
Sbjct: 214 NKLKAEMDSHKETKDKLKETTTKLTQAKEE-----ADQIRKNCQDMIKTYQESEEIKSNE 268

Query: 304 IWKELQMTRGAL---LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDK------MAT 354
           +  +L++T+G L   ++ + +  +    K   L  L R  + EG +  +        +  
Sbjct: 269 LDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFK-EGMDELRTLRTKVKCLED 327

Query: 355 ELLDREQKIVKLQQTIDEQR---ENEKSMEQTMTQYENQLAALRLEVKRLR 402
           E L  E ++ K ++ I+ Q+   +N     +T  Q + QL   + E++ L+
Sbjct: 328 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLK 378



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 67/300 (22%), Positives = 123/300 (41%), Gaps = 30/300 (10%)

Query: 95  ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
           ERL+ E+ + ++K     +K   +     V++       L E+L + +   E LKE V S
Sbjct: 328 ERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQ----LQEQLQRGKQEIENLKEEVES 383

Query: 155 AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQ 214
             S++   +  I    ++  +     E    K+  L+   N L  +    +    +L+ Q
Sbjct: 384 LNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQ 443

Query: 215 AETAEQV---AQSRVSEQ----KARTEFLQAKVA-EQEKSKAVAXXXXXXXXXXXXXXXX 266
            E  +Q     +SR+ ++    K   + LQA++A  Q + KA++                
Sbjct: 444 CEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRK 503

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
              S +D + +L   + RR L+ V   E+   D+E         + G+L        +S 
Sbjct: 504 HASSIKDLTKQL--QQARRKLDQV---ESGSYDKEVSSMGSRSSSSGSL------NARSS 552

Query: 327 AEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQ 386
           AE  S  N+ S +A     ++F       L++R   IV+LQ+    + E  + ME  + Q
Sbjct: 553 AEDRSPENTGSSVA----VDNFPQVDKAMLIER---IVRLQKAHARKNEKIEFMEDHIKQ 605


>AF114488-1|AAD29953.1| 1220|Homo sapiens intersectin short isoform
           protein.
          Length = 1220

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isoform
           protein.
          Length = 1721

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein.
          Length = 1261

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 55/259 (21%), Positives = 106/259 (40%), Gaps = 10/259 (3%)

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           E L  +RA  +A  + +   +  L   +   + ++ Q  D +   + A+K+ K+  +   
Sbjct: 215 ETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKE 274

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           R   E +     ++      E AE+ A+S   E     E L+ +V E      +      
Sbjct: 275 RYMEEMADTADAIEMATLDKEMAEERAESLQQE----VEALKERVDELTTDLEILKAEIE 330

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIW-KELQMTRG 313
                      QL+   +++ RL D + R R L     +E+    +  E   +EL++ R 
Sbjct: 331 EKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ 390

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DE 372
              R +EEL Q+ +  D       ++    G E   + +    L+ E+K+ +L++T+ D 
Sbjct: 391 QRERLQEELSQAESTIDEL---KEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDL 447

Query: 373 QRENEKSMEQTMTQYENQL 391
           +  NE + E      E +L
Sbjct: 448 EAMNEMNDELQENARETEL 466



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 64/255 (25%), Positives = 114/255 (44%), Gaps = 31/255 (12%)

Query: 3   KNLIAQQNSLLEHYAILR--DMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTER-LH 59
           + L AQ   L E    LR    E +A +      ++++    EWK++  E   D +R L 
Sbjct: 201 EGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLK 260

Query: 60  RMVAGIAENLKAKINFSLEIA------KIPWLDRDTMIKKIERLQKENSILQHKVDETS- 112
                  E L+AK  +  E+A      ++  LD++   ++ E LQ+E   L+ +VDE + 
Sbjct: 261 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 320

Query: 113 -----KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIA 167
                K E EE       S SY  + L E+ ++ + A   +++ ++S+E    V      
Sbjct: 321 DLEILKAEIEEKGSDGAAS-SYQLKQLEEQNARLKDALVRMRD-LSSSEKQEHV------ 372

Query: 168 TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVS 227
            L++ ++    E E+ +++ + L++       E S A   + EL+EQ + A   A+  V 
Sbjct: 373 KLQKLMEKKNQELEVVRQQRERLQE-------ELSQAESTIDELKEQVDAA-LGAEEMVE 424

Query: 228 EQKARTEFLQAKVAE 242
               R   L+ KV E
Sbjct: 425 MLTDRNLNLEEKVRE 439



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 47/230 (20%), Positives = 101/230 (43%), Gaps = 7/230 (3%)

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ--SRVSEQK 230
           L     E E  + + +DLE+ +  L ++R+    K+KEL +     EQV +  S++ EQ+
Sbjct: 193 LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQ 252

Query: 231 ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYV 290
           A  +  + K A +E  +A+                 ++ +             ++ +E +
Sbjct: 253 ADLQ-RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEAL 311

Query: 291 PCKENEPTDRETEIWK-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQ 349
             + +E T  + EI K E++        S  +L+Q   +     ++L R+     +E  +
Sbjct: 312 KERVDELT-TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQE 370

Query: 350 DKMATELLDRE-QKIVKLQQTIDEQRENEKSMEQTMTQYENQL-AALRLE 397
                +L++++ Q++  ++Q  +  +E     E T+ + + Q+ AAL  E
Sbjct: 371 HVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAE 420



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 6/118 (5%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVARARI--ATLERQLKDTKAEFEI-AKKKHKDLE 191
           N+EL   R  RE L+E ++ AES +   + ++  A    ++ +   +  +  ++K ++L 
Sbjct: 382 NQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELR 441

Query: 192 QLVNRL-AIERSHATVKVKELREQAETAEQ--VAQSRVSEQKARTEFLQAKVAEQEKS 246
           + V  L A+   +  ++      + E  EQ  +A +RV E + R E  Q  VA+ +++
Sbjct: 442 ETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQT 499


>AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form
           protein.
          Length = 1721

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>AF064243-1|AAC78610.1| 1220|Homo sapiens intersectin short form
           protein.
          Length = 1220

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 76/344 (22%), Positives = 134/344 (38%), Gaps = 19/344 (5%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR-LEVKR--LRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            +  +S  Q +  + NQL  LR +  K+   +     ++ +   E + +I++L  Q E  
Sbjct: 590 EKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEA 649

Query: 431 SRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDG 474
            R                + H+R   L       R++     DG
Sbjct: 650 QRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDG 693


>AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform
           protein.
          Length = 1144

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 55/259 (21%), Positives = 106/259 (40%), Gaps = 10/259 (3%)

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           E L  +RA  +A  + +   +  L   +   + ++ Q  D +   + A+K+ K+  +   
Sbjct: 98  ETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKE 157

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           R   E +     ++      E AE+ A+S   E     E L+ +V E      +      
Sbjct: 158 RYMEEMADTADAIEMATLDKEMAEERAESLQQE----VEALKERVDELTTDLEILKAEIE 213

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIW-KELQMTRG 313
                      QL+   +++ RL D + R R L     +E+    +  E   +EL++ R 
Sbjct: 214 EKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ 273

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DE 372
              R +EEL Q+ +  D       ++    G E   + +    L+ E+K+ +L++T+ D 
Sbjct: 274 QRERLQEELSQAESTIDEL---KEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDL 330

Query: 373 QRENEKSMEQTMTQYENQL 391
           +  NE + E      E +L
Sbjct: 331 EAMNEMNDELQENARETEL 349



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 64/255 (25%), Positives = 114/255 (44%), Gaps = 31/255 (12%)

Query: 3   KNLIAQQNSLLEHYAILR--DMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTER-LH 59
           + L AQ   L E    LR    E +A +      ++++    EWK++  E   D +R L 
Sbjct: 84  EGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLK 143

Query: 60  RMVAGIAENLKAKINFSLEIA------KIPWLDRDTMIKKIERLQKENSILQHKVDETS- 112
                  E L+AK  +  E+A      ++  LD++   ++ E LQ+E   L+ +VDE + 
Sbjct: 144 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 203

Query: 113 -----KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIA 167
                K E EE       S SY  + L E+ ++ + A   +++ ++S+E    V      
Sbjct: 204 DLEILKAEIEEKGSDGAAS-SYQLKQLEEQNARLKDALVRMRD-LSSSEKQEHV------ 255

Query: 168 TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVS 227
            L++ ++    E E+ +++ + L++       E S A   + EL+EQ + A   A+  V 
Sbjct: 256 KLQKLMEKKNQELEVVRQQRERLQE-------ELSQAESTIDELKEQVDAA-LGAEEMVE 307

Query: 228 EQKARTEFLQAKVAE 242
               R   L+ KV E
Sbjct: 308 MLTDRNLNLEEKVRE 322



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 47/230 (20%), Positives = 101/230 (43%), Gaps = 7/230 (3%)

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ--SRVSEQK 230
           L     E E  + + +DLE+ +  L ++R+    K+KEL +     EQV +  S++ EQ+
Sbjct: 76  LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQ 135

Query: 231 ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYV 290
           A  +  + K A +E  +A+                 ++ +             ++ +E +
Sbjct: 136 ADLQ-RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEAL 194

Query: 291 PCKENEPTDRETEIWK-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQ 349
             + +E T  + EI K E++        S  +L+Q   +     ++L R+     +E  +
Sbjct: 195 KERVDELT-TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQE 253

Query: 350 DKMATELLDRE-QKIVKLQQTIDEQRENEKSMEQTMTQYENQL-AALRLE 397
                +L++++ Q++  ++Q  +  +E     E T+ + + Q+ AAL  E
Sbjct: 254 HVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAE 303



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 6/118 (5%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVARARI--ATLERQLKDTKAEFEI-AKKKHKDLE 191
           N+EL   R  RE L+E ++ AES +   + ++  A    ++ +   +  +  ++K ++L 
Sbjct: 265 NQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELR 324

Query: 192 QLVNRL-AIERSHATVKVKELREQAETAEQ--VAQSRVSEQKARTEFLQAKVAEQEKS 246
           + V  L A+   +  ++      + E  EQ  +A +RV E + R E  Q  VA+ +++
Sbjct: 325 ETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQT 382


>AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform
           protein.
          Length = 1278

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 55/259 (21%), Positives = 106/259 (40%), Gaps = 10/259 (3%)

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           E L  +RA  +A  + +   +  L   +   + ++ Q  D +   + A+K+ K+  +   
Sbjct: 232 ETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKE 291

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           R   E +     ++      E AE+ A+S   E     E L+ +V E      +      
Sbjct: 292 RYMEEMADTADAIEMATLDKEMAEERAESLQQE----VEALKERVDELTTDLEILKAEIE 347

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIW-KELQMTRG 313
                      QL+   +++ RL D + R R L     +E+    +  E   +EL++ R 
Sbjct: 348 EKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ 407

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DE 372
              R +EEL Q+ +  D       ++    G E   + +    L+ E+K+ +L++T+ D 
Sbjct: 408 QRERLQEELSQAESTIDEL---KEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDL 464

Query: 373 QRENEKSMEQTMTQYENQL 391
           +  NE + E      E +L
Sbjct: 465 EAMNEMNDELQENARETEL 483



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 64/255 (25%), Positives = 114/255 (44%), Gaps = 31/255 (12%)

Query: 3   KNLIAQQNSLLEHYAILR--DMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTER-LH 59
           + L AQ   L E    LR    E +A +      ++++    EWK++  E   D +R L 
Sbjct: 218 EGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLK 277

Query: 60  RMVAGIAENLKAKINFSLEIA------KIPWLDRDTMIKKIERLQKENSILQHKVDETS- 112
                  E L+AK  +  E+A      ++  LD++   ++ E LQ+E   L+ +VDE + 
Sbjct: 278 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 337

Query: 113 -----KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIA 167
                K E EE       S SY  + L E+ ++ + A   +++ ++S+E    V      
Sbjct: 338 DLEILKAEIEEKGSDGAAS-SYQLKQLEEQNARLKDALVRMRD-LSSSEKQEHV------ 389

Query: 168 TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVS 227
            L++ ++    E E+ +++ + L++       E S A   + EL+EQ + A   A+  V 
Sbjct: 390 KLQKLMEKKNQELEVVRQQRERLQE-------ELSQAESTIDELKEQVDAA-LGAEEMVE 441

Query: 228 EQKARTEFLQAKVAE 242
               R   L+ KV E
Sbjct: 442 MLTDRNLNLEEKVRE 456



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 47/230 (20%), Positives = 101/230 (43%), Gaps = 7/230 (3%)

Query: 173 LKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQ--SRVSEQK 230
           L     E E  + + +DLE+ +  L ++R+    K+KEL +     EQV +  S++ EQ+
Sbjct: 210 LPSPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQ 269

Query: 231 ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYV 290
           A  +  + K A +E  +A+                 ++ +             ++ +E +
Sbjct: 270 ADLQ-RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEAL 328

Query: 291 PCKENEPTDRETEIWK-ELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQ 349
             + +E T  + EI K E++        S  +L+Q   +     ++L R+     +E  +
Sbjct: 329 KERVDELT-TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQE 387

Query: 350 DKMATELLDRE-QKIVKLQQTIDEQRENEKSMEQTMTQYENQL-AALRLE 397
                +L++++ Q++  ++Q  +  +E     E T+ + + Q+ AAL  E
Sbjct: 388 HVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAE 437



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 6/118 (5%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVARARI--ATLERQLKDTKAEFEI-AKKKHKDLE 191
           N+EL   R  RE L+E ++ AES +   + ++  A    ++ +   +  +  ++K ++L 
Sbjct: 399 NQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELR 458

Query: 192 QLVNRL-AIERSHATVKVKELREQAETAEQ--VAQSRVSEQKARTEFLQAKVAEQEKS 246
           + V  L A+   +  ++      + E  EQ  +A +RV E + R E  Q  VA+ +++
Sbjct: 459 ETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQT 516


>AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein.
          Length = 1286

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 47/210 (22%), Positives = 88/210 (41%), Gaps = 25/210 (11%)

Query: 40  SNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK 99
           S  E + R  +   DTE+  R  A        +I  S ++ ++   +    I  +++  K
Sbjct: 329 SQFECRVRELQRMLDTEKQSRARAD------QRITESRQVVELAVKEHKAEILALQQALK 382

Query: 100 ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML 159
           E  +   K +  S K N+    H +     N + L ++L  ER  ++ L E  A  +  +
Sbjct: 383 EQKL---KAESLSDKLNDLEKKHAMLE--MNARSLQQKLETERELKQRLLEEQAKLQQQM 437

Query: 160 RVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE 219
            + +  I  L + L++     ++ K +  DLE  +  + +  SH  VK+           
Sbjct: 438 DLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKM----------- 486

Query: 220 QVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
              +  +S+Q    +FLQAK+ +  K K V
Sbjct: 487 ---EGTISQQTKLIDFLQAKMDQPAKKKKV 513



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 62/291 (21%), Positives = 122/291 (41%), Gaps = 28/291 (9%)

Query: 152 VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
           + S +  +   +     LE Q+ D +A  +   +K +  E   + L  E+S    +V+EL
Sbjct: 279 LTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVREL 338

Query: 212 REQAETAEQ--------VAQSR------VSEQKARTEFLQAKVAEQE-KSKAVA------ 250
           +   +T +Q        + +SR      V E KA    LQ  + EQ+ K+++++      
Sbjct: 339 QRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDL 398

Query: 251 XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM 310
                           +L++ R+   RL++ E+ +  + +  ++N    R T+  +E  +
Sbjct: 399 EKKHAMLEMNARSLQQKLETERELKQRLLE-EQAKLQQQMDLQKNH-IFRLTQGLQE-AL 455

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATEL---LDREQKIVKLQ 367
            R  LL++E    + + E    L S  ++   EGT S Q K+   L   +D+  K  K+ 
Sbjct: 456 DRADLLKTERSDLEYQLENIQVLYSHEKVKM-EGTISQQTKLIDFLQAKMDQPAKKKKVP 514

Query: 368 QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQT 418
              +E +   +  +    + E  L   R+E++  R    + K   +P   T
Sbjct: 515 LQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPST 565



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 65/339 (19%), Positives = 122/339 (35%), Gaps = 21/339 (6%)

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
           V+    N    N  L  +R  + A +E+++           +   LE Q  + K E ++ 
Sbjct: 56  VELSEANKLAANSSLFTQRNMK-AQEEMISELRQQKFYLETQAGKLEAQ--NRKLEEQLE 112

Query: 184 KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF--LQAKVA 241
           K  H+D       L +E     V ++   ++ E   Q+ + ++S Q+  ++   LQA  A
Sbjct: 113 KISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARA 172

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
             E     A                 L + RD   R  D  R  C      +E    ++ 
Sbjct: 173 ALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQ--LNQL 230

Query: 302 TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
           TE   EL      L    ++L ++    D  +   S +          D +  E+ +RE 
Sbjct: 231 TEDNAELNNQNFYL---SKQLDEASGANDEIVQLRSEV----------DHLRREITEREM 277

Query: 362 KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNY-DCYSKDVSYPELQTEI 420
           ++   +QT++  +     +E+ +   E     L  + ++   +      + S  E +   
Sbjct: 278 QLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRE 337

Query: 421 LDLHLQVETLSRERTALITAAASRALMLERHERAADLFA 459
           L   L  E  SR R       + + + L   E  A++ A
Sbjct: 338 LQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILA 376


>AB209625-1|BAD92862.1|  459|Homo sapiens dynactin 1 isoform 1
           variant protein.
          Length = 459

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 55/259 (21%), Positives = 106/259 (40%), Gaps = 10/259 (3%)

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           E L  +RA  +A  + +   +  L   +   + ++ Q  D +   + A+K+ K+  +   
Sbjct: 57  ETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKE 116

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           R   E +     ++      E AE+ A+S   E     E L+ +V E      +      
Sbjct: 117 RYMEEMADTADAIEMATLDKEMAEERAESLQQE----VEALKERVDELTTDLEILKAEIE 172

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVD-MERRRCLEYVPCKENEPTDRETEIW-KELQMTRG 313
                      QL+   +++ RL D + R R L     +E+    +  E   +EL++ R 
Sbjct: 173 EKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQ 232

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DE 372
              R +EEL Q+ +  D       ++    G E   + +    L+ E+K+ +L++T+ D 
Sbjct: 233 QRERLQEELSQAESTIDEL---KEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDL 289

Query: 373 QRENEKSMEQTMTQYENQL 391
           +  NE + E      E +L
Sbjct: 290 EAMNEMNDELQENARETEL 308



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 64/255 (25%), Positives = 114/255 (44%), Gaps = 31/255 (12%)

Query: 3   KNLIAQQNSLLEHYAILR--DMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTER-LH 59
           + L AQ   L E    LR    E +A +      ++++    EWK++  E   D +R L 
Sbjct: 43  EGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLK 102

Query: 60  RMVAGIAENLKAKINFSLEIA------KIPWLDRDTMIKKIERLQKENSILQHKVDETS- 112
                  E L+AK  +  E+A      ++  LD++   ++ E LQ+E   L+ +VDE + 
Sbjct: 103 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 162

Query: 113 -----KKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIA 167
                K E EE       S SY  + L E+ ++ + A   +++ ++S+E    V      
Sbjct: 163 DLEILKAEIEEKGSDGAAS-SYQLKQLEEQNARLKDALVRMRD-LSSSEKQEHV------ 214

Query: 168 TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVS 227
            L++ ++    E E+ +++ + L++       E S A   + EL+EQ + A   A+  V 
Sbjct: 215 KLQKLMEKKNQELEVVRQQRERLQE-------ELSQAESTIDELKEQVDAA-LGAEEMVE 266

Query: 228 EQKARTEFLQAKVAE 242
               R   L+ KV E
Sbjct: 267 MLTDRNLNLEEKVRE 281



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 53/251 (21%), Positives = 113/251 (45%), Gaps = 9/251 (3%)

Query: 152 VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
           V  A S+L   R+ + T +R+    + E E  + + +DLE+ +  L ++R+    K+KEL
Sbjct: 16  VLCASSVLVERRSGLCT-DREASPLQEE-EGLRAQVRDLEEKLETLRLKRAEDKAKLKEL 73

Query: 212 REQAETAEQVAQ--SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQ 269
            +     EQV +  S++ EQ+A  +  + K A +E  +A+                 ++ 
Sbjct: 74  EKHKIQLEQVQEWKSKMQEQQADLQ-RRLKEARKEAKEALEAKERYMEEMADTADAIEMA 132

Query: 270 SFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWK-ELQMTRGALLRSEEELRQSRAE 328
           +             ++ +E +  + +E T  + EI K E++        S  +L+Q   +
Sbjct: 133 TLDKEMAEERAESLQQEVEALKERVDELT-TDLEILKAEIEEKGSDGAASSYQLKQLEEQ 191

Query: 329 KDSFLNSLSRIAQGEGTESFQDKMATELLDRE-QKIVKLQQTIDEQRENEKSMEQTMTQY 387
                ++L R+     +E  +     +L++++ Q++  ++Q  +  +E     E T+ + 
Sbjct: 192 NARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDEL 251

Query: 388 ENQL-AALRLE 397
           + Q+ AAL  E
Sbjct: 252 KEQVDAALGAE 262



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 6/118 (5%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVARARI--ATLERQLKDTKAEFEI-AKKKHKDLE 191
           N+EL   R  RE L+E ++ AES +   + ++  A    ++ +   +  +  ++K ++L 
Sbjct: 224 NQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELR 283

Query: 192 QLVNRL-AIERSHATVKVKELREQAETAEQ--VAQSRVSEQKARTEFLQAKVAEQEKS 246
           + V  L A+   +  ++      + E  EQ  +A +RV E + R E  Q  VA+ +++
Sbjct: 284 ETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQT 341


>AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein.
          Length = 1559

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 47/210 (22%), Positives = 88/210 (41%), Gaps = 25/210 (11%)

Query: 40  SNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK 99
           S  E + R  +   DTE+  R  A        +I  S ++ ++   +    I  +++  K
Sbjct: 603 SQFECRVRELQRMLDTEKQSRARAD------QRITESRQVVELAVKEHKAEILALQQALK 656

Query: 100 ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML 159
           E  +   K +  S K N+    H +     N + L ++L  ER  ++ L E  A  +  +
Sbjct: 657 EQKL---KAESLSDKLNDLEKKHAMLE--MNARSLQQKLETERELKQRLLEEQAKLQQQM 711

Query: 160 RVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE 219
            + +  I  L + L++     ++ K +  DLE  +  + +  SH  VK+           
Sbjct: 712 DLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKM----------- 760

Query: 220 QVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
              +  +S+Q    +FLQAK+ +  K K V
Sbjct: 761 ---EGTISQQTKLIDFLQAKMDQPAKKKKV 787



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 62/291 (21%), Positives = 122/291 (41%), Gaps = 28/291 (9%)

Query: 152 VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
           + S +  +   +     LE Q+ D +A  +   +K +  E   + L  E+S    +V+EL
Sbjct: 553 LTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVREL 612

Query: 212 REQAETAEQ--------VAQSR------VSEQKARTEFLQAKVAEQE-KSKAVA------ 250
           +   +T +Q        + +SR      V E KA    LQ  + EQ+ K+++++      
Sbjct: 613 QRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDL 672

Query: 251 XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM 310
                           +L++ R+   RL++ E+ +  + +  ++N    R T+  +E  +
Sbjct: 673 EKKHAMLEMNARSLQQKLETERELKQRLLE-EQAKLQQQMDLQKNH-IFRLTQGLQE-AL 729

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATEL---LDREQKIVKLQ 367
            R  LL++E    + + E    L S  ++   EGT S Q K+   L   +D+  K  K+ 
Sbjct: 730 DRADLLKTERSDLEYQLENIQVLYSHEKVKM-EGTISQQTKLIDFLQAKMDQPAKKKKVP 788

Query: 368 QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQT 418
              +E +   +  +    + E  L   R+E++  R    + K   +P   T
Sbjct: 789 LQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPST 839



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 65/339 (19%), Positives = 122/339 (35%), Gaps = 21/339 (6%)

Query: 124 VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
           V+    N    N  L  +R  + A +E+++           +   LE Q  + K E ++ 
Sbjct: 330 VELSEANKLAANSSLFTQRNMK-AQEEMISELRQQKFYLETQAGKLEAQ--NRKLEEQLE 386

Query: 184 KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF--LQAKVA 241
           K  H+D       L +E     V ++   ++ E   Q+ + ++S Q+  ++   LQA  A
Sbjct: 387 KISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARA 446

Query: 242 EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
             E     A                 L + RD   R  D  R  C      +E    ++ 
Sbjct: 447 ALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQ--LNQL 504

Query: 302 TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
           TE   EL      L    ++L ++    D  +   S +          D +  E+ +RE 
Sbjct: 505 TEDNAELNNQNFYL---SKQLDEASGANDEIVQLRSEV----------DHLRREITEREM 551

Query: 362 KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNY-DCYSKDVSYPELQTEI 420
           ++   +QT++  +     +E+ +   E     L  + ++   +      + S  E +   
Sbjct: 552 QLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRE 611

Query: 421 LDLHLQVETLSRERTALITAAASRALMLERHERAADLFA 459
           L   L  E  SR R       + + + L   E  A++ A
Sbjct: 612 LQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILA 650



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 66/353 (18%), Positives = 148/353 (41%), Gaps = 24/353 (6%)

Query: 138 LSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL 197
           LS++    +A +   +  E  L       ++L+R L+  +A  E++++  K L QL++ +
Sbjct: 34  LSQKEVELKASETQRSLLEQDLATYITECSSLKRSLE--QARMEVSQEDDKAL-QLLHDI 90

Query: 198 AIERSHATVKVKELREQAETAE------QVAQSRVSEQKARTEFLQAKVAEQ----EKSK 247
             E+S    ++KE   QA+  E      Q+ +  VS ++ R++  ++++ E     E+ K
Sbjct: 91  R-EQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARR-RSDLYESELRESRLAAEEFK 148

Query: 248 AVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKE 307
             A                ++  +    +  ++ E++  ++ +  K  +     TE  + 
Sbjct: 149 RKATECQHKLLKAKDQGKPEVGEYA--KLEKINAEQQLKIQELQEKLEKAVKASTEATEL 206

Query: 308 LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
           LQ  R A  R+E EL + +  +DS      ++ +    E  ++K     +  +   V L+
Sbjct: 207 LQNIRQAKERAERELEKLQNREDSSEGIRKKLVE---AEELEEKHREAQVSAQHLEVHLK 263

Query: 368 QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
           Q      E  K ++  + +       L   ++R    + + K     E +  I  +  ++
Sbjct: 264 QKEQHYEEKIKVLDNQIKKDLADKETLENMMQR-HEEEAHEKGKILSEQKAMINAMDSKI 322

Query: 428 ETLSRERTALITA---AASRALMLERHERAADLFARMVRARKDLAALLDGRID 477
            +L +    L  A   AA+ +L  +R+ +A +     +R +K       G+++
Sbjct: 323 RSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLE 375


>AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.
          Length = 1635

 Score = 44.0 bits (99), Expect = 0.001
 Identities = 78/384 (20%), Positives = 170/384 (44%), Gaps = 32/384 (8%)

Query: 96   RLQKENSILQ-HKVDET-SKKE--NEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEV 151
            RL+ +N ++Q  +V +T SK E  NE+  C   +  +    +  +EL   RA    LK+ 
Sbjct: 823  RLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDS 882

Query: 152  VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
            +A + S+     + +  LE ++       E  +K+ K+ E+ +N++ +    A  ++   
Sbjct: 883  LAKSPSVKNDPLSSVKELEEKI-------ENLEKECKEKEEKINKIKLVAVKAKKELDSS 935

Query: 212  REQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSF 271
            R++ +T ++  +S  SE+   +  ++  +   E  K +                 + +  
Sbjct: 936  RKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNL----LLEYEKQSEQLDVEKERA 991

Query: 272  RDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE-EELRQSRAEKD 330
             +   R+ D+ R+     + C+     + +     E   +   LL  +  E+++++A  D
Sbjct: 992  NNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVD 1051

Query: 331  SFLNS-----LSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT 385
              L +       +I +   T +  +++  + L +E+K  +LQ+T+ E    +K  +QT T
Sbjct: 1052 KELEAEKLQKEQKIKEHATTVNELEELQVQ-LQKEKK--QLQKTMQELELVKKDAQQT-T 1107

Query: 386  QYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRA 445
                ++A     +K L N    +K+    +L+ EI     + ETL  E T+L      ++
Sbjct: 1108 LMNMEIADYERLMKEL-NQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSL------QS 1160

Query: 446  LMLERHERAADLFARMVRARKDLA 469
             + +  E+   +   +V+ +K+LA
Sbjct: 1161 SVQQYEEKNTKIKQLLVKTKKELA 1184



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 61/318 (19%), Positives = 128/318 (40%), Gaps = 19/318 (5%)

Query: 137  ELSKE-RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EL KE +  +E         +S+LR        L ++L++ ++E E  +    +++    
Sbjct: 761  ELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANE 820

Query: 196  RLAIERSHATVKVKELREQAETAE---QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
            +  +E  +  ++V+E+ +    +E   +  +  + E +     L+ K     +++ +   
Sbjct: 821  KTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLK 880

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                           L S ++   ++ ++E+  C E    K N+      +  KEL  +R
Sbjct: 881  DSLAKSPSVKND--PLSSVKELEEKIENLEKE-CKEKEE-KINKIKLVAVKAKKELDSSR 936

Query: 313  GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
                  +EEL   R+EKD    S+  + Q  G ES+++     LL+ E    K  + +D 
Sbjct: 937  KETQTVKEELESLRSEKDQLSASMRDLIQ--GAESYKNL----LLEYE----KQSEQLDV 986

Query: 373  QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
            ++E   + E  +     QL    L+ + + N D          LQ+    L +Q+  + R
Sbjct: 987  EKERANNFEHRIEDLTRQLRNSTLQCETI-NSDNEDLLARIETLQSNAKLLEVQILEVQR 1045

Query: 433  ERTALITAAASRALMLER 450
             +  +     +  L  E+
Sbjct: 1046 AKAMVDKELEAEKLQKEQ 1063



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 72/386 (18%), Positives = 159/386 (41%), Gaps = 40/386 (10%)

Query: 92   KKIERLQKENSILQHKVDET-SKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
            K+++  +KE   ++ +++   S+K+        +  G+ +Y+ L  E  K+    +  KE
Sbjct: 930  KELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKE 989

Query: 151  VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE 210
               + E        RI  L RQL+++  + E     ++DL   +  L        V++ E
Sbjct: 990  RANNFEH-------RIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILE 1042

Query: 211  L-REQAETAEQV-AQSRVSEQKAR------TEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
            + R +A   +++ A+    EQK +       E  + +V  Q++ K +             
Sbjct: 1043 VQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKD 1102

Query: 263  XXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKEN--EPTDRETEIWKELQMTRGALLRS 318
                 L      ++ + D ER  +   + +  K N  E  ++E +I K+ Q T    + S
Sbjct: 1103 AQQTTLM-----NMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITS 1157

Query: 319  EEELRQSRAEKDSFLNSL-----SRIAQGEGTES----FQDKMATELLDREQKI----VK 365
             +   Q   EK++ +  L       +A  +  E+     Q  +  EL   +Q++    ++
Sbjct: 1158 LQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQ 1217

Query: 366  LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
            L +   E+ +  + ++ +  Q++  L+A +  V  L+  +C +       + +E     +
Sbjct: 1218 LAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQE-ECRAAKAEQATVTSEFESYKV 1276

Query: 426  QV-ETLSRERTALITAAASRALMLER 450
            +V   L +++   ++ A +     ER
Sbjct: 1277 RVHNVLKQQKNKSMSQAETEGAKQER 1302


>X04201-1|CAA27798.1|  285|Homo sapiens protein ( Human skeletal
           muscle 1.3 kb mRNA for tropomyosin. ).
          Length = 285

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 56/253 (22%), Positives = 108/253 (42%), Gaps = 20/253 (7%)

Query: 162 ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQV 221
           A A     E + K  + E    +KK K  E  +++     S A    +E  E AE     
Sbjct: 26  AEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY----SEALKDAQEKLELAEKKAAD 81

Query: 222 AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
           A++ V+    R + ++ ++   ++  A A                 ++   +R+++  D 
Sbjct: 82  AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALK--DE 139

Query: 282 ERRRCLEYVPCKEN----EPTDRE-TEIWKELQMTRGALLRSEE--ELRQSRA-----EK 329
           E+   L+ +  KE     E  DR+  E+ ++L +  G L R+EE  EL +S+      E 
Sbjct: 140 EKME-LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEEL 198

Query: 330 DSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYE 388
            +  N+L  + AQ E     +DK   E+     K+ + +   +    +   +E+T+   E
Sbjct: 199 KNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 258

Query: 389 NQLAALRLEVKRL 401
           ++L A +L+ K +
Sbjct: 259 DELYAQKLKYKAI 271



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 31/160 (19%), Positives = 73/160 (45%), Gaps = 9/160 (5%)

Query: 92  KKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
           ++++R Q+  +    K++E  K  +E E     +++ +   +   E++  +    +  K 
Sbjct: 98  EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE---EKMELQEIQLKEAKH 154

Query: 151 VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ----LVNRLAIERSHATV 206
           +   A+        ++  +E  L+ T+   E+A+ K  +LE+    + N L    + A  
Sbjct: 155 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAE- 213

Query: 207 KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
           K  +  ++ E   ++   ++ E + R EF +  VA+ EK+
Sbjct: 214 KYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKT 253



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 30/160 (18%), Positives = 76/160 (47%), Gaps = 7/160 (4%)

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           +E ++K+  +L  K+D+ +  +  E      +      + L +EL+  +   +  ++ + 
Sbjct: 2   MEAIKKKMQML--KLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELD 59

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
                L+ A+ ++   E++  D +AE     ++ + +E+ ++R     + A  K++E  +
Sbjct: 60  KYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 119

Query: 214 QAETAE---QVAQSRV--SEQKARTEFLQAKVAEQEKSKA 248
            A+ +E   +V ++R    E+K   + +Q K A+    +A
Sbjct: 120 AADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 159



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 16/127 (12%)

Query: 346 ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN-Y 404
           E+ + KM    LD+E  + + +Q   EQ++ E+  +    Q E++LAA++ ++K   +  
Sbjct: 3   EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSK----QLEDELAAMQKKLKGTEDEL 58

Query: 405 DCYSKDVSYPELQTEI-----LDLHLQVETLSRERTALITAAASRALMLERHERAADLFA 459
           D YS+ +   + + E+      D   +V +L+R R  L+     RA      ER A    
Sbjct: 59  DKYSEALKDAQEKLELAEKKAADAEAEVASLNR-RIQLVEEELDRA-----QERLATALQ 112

Query: 460 RMVRARK 466
           ++  A K
Sbjct: 113 KLEEAEK 119


>BC052988-1|AAH52988.1|  980|Homo sapiens retinoic acid induced 14
           protein.
          Length = 980

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 67/315 (21%), Positives = 132/315 (41%), Gaps = 41/315 (13%)

Query: 136 EELSKE-RAAREALKEVVASAESM--------LRVARARIATLERQLKDTKAEFEIAKKK 186
           EE  KE  + ++ +K  + S ESM        LRV    I  L++ L++   E E  K+K
Sbjct: 493 EEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEK 552

Query: 187 HKDLEQLVNRLAIERSHATV---KVKELREQAETAEQVAQSRVSE--------QKARTEF 235
            ++LE+ +    +ER   TV    V+E  E   +   V ++   E        Q+A+ E 
Sbjct: 553 VRELEEKL----VEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEI 608

Query: 236 LQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL--------QSFRDRSIRLVDMERRRCL 287
           ++ K   + +    A                +L        Q +++    L D  +R+ L
Sbjct: 609 MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 668

Query: 288 EYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES 347
           E V  +     + E    K +Q+T  +  ++E+ L + +++    LN L+++ Q      
Sbjct: 669 EDVTAEYIHKAEHE----KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ---LVD 721

Query: 348 FQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV--KRLRNYD 405
            Q + +  + +  Q I  L+    E  E   ++++ +   E ++A L  ++  ++    D
Sbjct: 722 AQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTD 781

Query: 406 CYSKDVSYPELQTEI 420
                 SY +LQ+ +
Sbjct: 782 AMVPRSSYEKLQSSL 796



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 3/107 (2%)

Query: 142 RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
           R A + ++E +++ +  L      +A LE+QL + KA    A       E+L + L  E 
Sbjct: 741 RTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEV 800

Query: 202 SHATVKVKE-LREQAETAEQVAQ--SRVSEQKARTEFLQAKVAEQEK 245
           S    K+KE ++E+ +   +V Q  S VS+ K   E +Q  +  +E+
Sbjct: 801 SVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQ 847



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 43/180 (23%), Positives = 82/180 (45%), Gaps = 20/180 (11%)

Query: 85  LDRDTMIKKIERLQKENS--ILQH----KVDETSKKENEEPPCH---PVQSGSYNYQVLN 135
           L+  T +K++   QKENS  I +H        T+ KE EE   +    + S       L 
Sbjct: 710 LNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLE 769

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           ++L +E+AA        +S E +     + ++ L  +LK++  E E   K H ++ Q+ +
Sbjct: 770 KQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKE---KVHSEVVQIRS 826

Query: 196 RLA-IERSHATVKVKELREQAETAE-----QVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
            ++ ++R    ++     ++ E  E     Q AQ  ++E K  +E   +   E++K K +
Sbjct: 827 EVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSE--SSSKLEEDKDKKI 884



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 71/379 (18%), Positives = 152/379 (40%), Gaps = 45/379 (11%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERA-- 143
           D    +++ ER +++   L+ K+ E  K    +PP    +    +Y  + E ++KE+A  
Sbjct: 538 DLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFL 597

Query: 144 ---AREALKEVVA---------------SAESMLRVARARIATLERQL-------KDTKA 178
               +EA +E++                 AE M       I  L +Q+       K+ +A
Sbjct: 598 FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQA 657

Query: 179 EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQA 238
           E E  +K+ K LE +      +  H  +       +A+  + +++ +    K   E  Q 
Sbjct: 658 ELEDYRKR-KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL 716

Query: 239 K-VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEP 297
           K + + +K  +V+                +++       ++ +++     E++  KE E 
Sbjct: 717 KQLVDAQKENSVSITEHLQVITTLRTAAKEMEE------KISNLK-----EHLASKEVEV 765

Query: 298 TDRETEIWKE-LQMTRGALLRSEEELRQSRAEKD-SFLNSLSR--IAQGEGTESFQDKMA 353
              E ++ +E   MT   + RS  E  QS  E + S L S  +  + + E   S   ++ 
Sbjct: 766 AKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR 825

Query: 354 TELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSY 413
           +E+   +++   +Q  +  + +    + Q   Q + +LA ++   +     +   KD   
Sbjct: 826 SEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLE-EDKDKKI 884

Query: 414 PELQTEILDLHLQVETLSR 432
            E+  E+  L   + +LS+
Sbjct: 885 NEMSKEVTKLKEALNSLSQ 903


>BC051733-1|AAH51733.1| 1026|Homo sapiens LUZP1 protein protein.
          Length = 1026

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 61/318 (19%), Positives = 137/318 (43%), Gaps = 26/318 (8%)

Query: 93  KIERLQKENSILQHKVDETSKKENE--EPPCHPVQSGSYNYQVLNE-ELSKERAAR-EAL 148
           K++ L +    L+       K E+E  +     +Q+   N  +L E E+ ++R  R E  
Sbjct: 19  KLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGK 78

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
            E +  AE + R+ + ++   E   ++ K+E E  +K+  +LE+L    +  ++  T   
Sbjct: 79  DEEIKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLC 138

Query: 209 KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL 268
             L E+    ++++        +  E L+ KV E E S+                   +L
Sbjct: 139 LSLNEERNLTKKIS--------SELEMLRVKVKELESSE-------DRLDKTEQSLASEL 183

Query: 269 QSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE--TEIWKELQMTRGALLRSEEELRQSR 326
           +  +  ++  V  ER+   E    KENE   +E   ++ +  +M R     +    R   
Sbjct: 184 EKLKSLTLSFVS-ERKYLNEKE--KENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDL 240

Query: 327 AEKDSFLNSL-SRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT 385
             +D   ++L S+ ++ +G   +  ++  E  ++ +      Q  ++ ++  + +E+  T
Sbjct: 241 RIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKT 300

Query: 386 QYENQLAALRLEVKRLRN 403
           Q ++   +L  E+K++++
Sbjct: 301 QIKH-FESLEEELKKMKS 317



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 38/191 (19%), Positives = 83/191 (43%), Gaps = 5/191 (2%)

Query: 45  KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSIL 104
           K  N ++  +   L R    I + + + +  S E  +   LD    ++   R + EN   
Sbjct: 222 KKMNRDYTRNASNLERNDLRIEDGISSTLP-SKESRRKGGLDYLKQVENETRNKSENEKN 280

Query: 105 QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
           +++ D   K  N+E     +++   +++ L EEL K ++    L++   S ++  ++  +
Sbjct: 281 RNQEDNKVKDLNQE--IEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLAS 338

Query: 165 RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
           ++  ++ Q+K  K E E  + + +D   L ++   ER+       E      TA +++  
Sbjct: 339 QLEEIKLQIKKQK-ELENGEVEGED-AFLSSKGRHERTKFRGHGSEASVSKHTARELSPQ 396

Query: 225 RVSEQKARTEF 235
              E+    EF
Sbjct: 397 HKRERLRNREF 407


>BC008425-1|AAH08425.1|  285|Homo sapiens tropomyosin 3 protein.
          Length = 285

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 56/253 (22%), Positives = 108/253 (42%), Gaps = 20/253 (7%)

Query: 162 ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQV 221
           A A     E + K  + E    +KK K  E  +++     S A    +E  E AE     
Sbjct: 26  AEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY----SEALKDAQEKLELAEKKAAD 81

Query: 222 AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
           A++ V+    R + ++ ++   ++  A A                 ++   +R+++  D 
Sbjct: 82  AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALK--DE 139

Query: 282 ERRRCLEYVPCKEN----EPTDRE-TEIWKELQMTRGALLRSEE--ELRQSRA-----EK 329
           E+   L+ +  KE     E  DR+  E+ ++L +  G L R+EE  EL +S+      E 
Sbjct: 140 EKME-LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEEL 198

Query: 330 DSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYE 388
            +  N+L  + AQ E     +DK   E+     K+ + +   +    +   +E+T+   E
Sbjct: 199 KNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 258

Query: 389 NQLAALRLEVKRL 401
           ++L A +L+ K +
Sbjct: 259 DELYAQKLKYKAI 271



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 31/160 (19%), Positives = 73/160 (45%), Gaps = 9/160 (5%)

Query: 92  KKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
           ++++R Q+  +    K++E  K  +E E     +++ +   +   E++  +    +  K 
Sbjct: 98  EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE---EKMELQEIQLKEAKH 154

Query: 151 VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ----LVNRLAIERSHATV 206
           +   A+        ++  +E  L+ T+   E+A+ K  +LE+    + N L    + A  
Sbjct: 155 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAE- 213

Query: 207 KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
           K  +  ++ E   ++   ++ E + R EF +  VA+ EK+
Sbjct: 214 KYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKT 253



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 30/160 (18%), Positives = 76/160 (47%), Gaps = 7/160 (4%)

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           +E ++K+  +L  K+D+ +  +  E      +      + L +EL+  +   +  ++ + 
Sbjct: 2   MEAIKKKMQML--KLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELD 59

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
                L+ A+ ++   E++  D +AE     ++ + +E+ ++R     + A  K++E  +
Sbjct: 60  KYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 119

Query: 214 QAETAE---QVAQSRV--SEQKARTEFLQAKVAEQEKSKA 248
            A+ +E   +V ++R    E+K   + +Q K A+    +A
Sbjct: 120 AADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 159



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 16/127 (12%)

Query: 346 ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN-Y 404
           E+ + KM    LD+E  + + +Q   EQ++ E+  +    Q E++LAA++ ++K   +  
Sbjct: 3   EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSK----QLEDELAAMQKKLKGTEDEL 58

Query: 405 DCYSKDVSYPELQTEI-----LDLHLQVETLSRERTALITAAASRALMLERHERAADLFA 459
           D YS+ +   + + E+      D   +V +L+R R  L+     RA      ER A    
Sbjct: 59  DKYSEALKDAQEKLELAEKKAADAEAEVASLNR-RIQLVEEELDRA-----QERLATALQ 112

Query: 460 RMVRARK 466
           ++  A K
Sbjct: 113 KLEEAEK 119


>BC008407-1|AAH08407.1|  285|Homo sapiens tropomyosin 3 protein.
          Length = 285

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 56/253 (22%), Positives = 108/253 (42%), Gaps = 20/253 (7%)

Query: 162 ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQV 221
           A A     E + K  + E    +KK K  E  +++     S A    +E  E AE     
Sbjct: 26  AEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY----SEALKDAQEKLELAEKKAAD 81

Query: 222 AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
           A++ V+    R + ++ ++   ++  A A                 ++   +R+++  D 
Sbjct: 82  AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALK--DE 139

Query: 282 ERRRCLEYVPCKEN----EPTDRE-TEIWKELQMTRGALLRSEE--ELRQSRA-----EK 329
           E+   L+ +  KE     E  DR+  E+ ++L +  G L R+EE  EL +S+      E 
Sbjct: 140 EKME-LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEEL 198

Query: 330 DSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYE 388
            +  N+L  + AQ E     +DK   E+     K+ + +   +    +   +E+T+   E
Sbjct: 199 KNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 258

Query: 389 NQLAALRLEVKRL 401
           ++L A +L+ K +
Sbjct: 259 DELYAQKLKYKAI 271



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 31/160 (19%), Positives = 73/160 (45%), Gaps = 9/160 (5%)

Query: 92  KKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
           ++++R Q+  +    K++E  K  +E E     +++ +   +   E++  +    +  K 
Sbjct: 98  EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE---EKMELQEIQLKEAKH 154

Query: 151 VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ----LVNRLAIERSHATV 206
           +   A+        ++  +E  L+ T+   E+A+ K  +LE+    + N L    + A  
Sbjct: 155 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAE- 213

Query: 207 KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
           K  +  ++ E   ++   ++ E + R EF +  VA+ EK+
Sbjct: 214 KYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKT 253



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 30/160 (18%), Positives = 76/160 (47%), Gaps = 7/160 (4%)

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           +E ++K+  +L  K+D+ +  +  E      +      + L +EL+  +   +  ++ + 
Sbjct: 2   MEAIKKKMQML--KLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELD 59

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
                L+ A+ ++   E++  D +AE     ++ + +E+ ++R     + A  K++E  +
Sbjct: 60  KYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 119

Query: 214 QAETAE---QVAQSRV--SEQKARTEFLQAKVAEQEKSKA 248
            A+ +E   +V ++R    E+K   + +Q K A+    +A
Sbjct: 120 AADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 159



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 16/127 (12%)

Query: 346 ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN-Y 404
           E+ + KM    LD+E  + + +Q   EQ++ E+  +    Q E++LAA++ ++K   +  
Sbjct: 3   EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSK----QLEDELAAMQKKLKGTEDEL 58

Query: 405 DCYSKDVSYPELQTEI-----LDLHLQVETLSRERTALITAAASRALMLERHERAADLFA 459
           D YS+ +   + + E+      D   +V +L+R R  L+     RA      ER A    
Sbjct: 59  DKYSEALKDAQEKLELAEKKAADAEAEVASLNR-RIQLVEEELDRA-----QERLATALQ 112

Query: 460 RMVRARK 466
           ++  A K
Sbjct: 113 KLEEAEK 119


>AY317139-1|AAP84319.1|  983|Homo sapiens RAI14 isoform protein.
          Length = 983

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 67/315 (21%), Positives = 132/315 (41%), Gaps = 41/315 (13%)

Query: 136 EELSKE-RAAREALKEVVASAESM--------LRVARARIATLERQLKDTKAEFEIAKKK 186
           EE  KE  + ++ +K  + S ESM        LRV    I  L++ L++   E E  K+K
Sbjct: 496 EEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEK 555

Query: 187 HKDLEQLVNRLAIERSHATV---KVKELREQAETAEQVAQSRVSE--------QKARTEF 235
            ++LE+ +    +ER   TV    V+E  E   +   V ++   E        Q+A+ E 
Sbjct: 556 VRELEEKL----VEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEI 611

Query: 236 LQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL--------QSFRDRSIRLVDMERRRCL 287
           ++ K   + +    A                +L        Q +++    L D  +R+ L
Sbjct: 612 MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 671

Query: 288 EYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES 347
           E V  +     + E    K +Q+T  +  ++E+ L + +++    LN L+++ Q      
Sbjct: 672 EDVTAEYIHKAEHE----KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ---LVD 724

Query: 348 FQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV--KRLRNYD 405
            Q + +  + +  Q I  L+    E  E   ++++ +   E ++A L  ++  ++    D
Sbjct: 725 AQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTD 784

Query: 406 CYSKDVSYPELQTEI 420
                 SY +LQ+ +
Sbjct: 785 AMVPRSSYEKLQSSL 799



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 3/107 (2%)

Query: 142 RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
           R A + ++E +++ +  L      +A LE+QL + KA    A       E+L + L  E 
Sbjct: 744 RTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEV 803

Query: 202 SHATVKVKE-LREQAETAEQVAQ--SRVSEQKARTEFLQAKVAEQEK 245
           S    K+KE ++E+ +   +V Q  S VS+ K   E +Q  +  +E+
Sbjct: 804 SVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQ 850



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 71/379 (18%), Positives = 152/379 (40%), Gaps = 45/379 (11%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERA-- 143
           D    +++ ER +++   L+ K+ E  K    +PP    +    +Y  + E ++KE+A  
Sbjct: 541 DLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFL 600

Query: 144 ---AREALKEVVA---------------SAESMLRVARARIATLERQL-------KDTKA 178
               +EA +E++                 AE M       I  L +Q+       K+ +A
Sbjct: 601 FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQA 660

Query: 179 EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQA 238
           E E  +K+ K LE +      +  H  +       +A+  + +++ +    K   E  Q 
Sbjct: 661 ELEDYRKR-KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL 719

Query: 239 K-VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEP 297
           K + + +K  +V+                +++       ++ +++     E++  KE E 
Sbjct: 720 KQLVDAQKENSVSITEHLQVITTLRTAAKEMEE------KISNLK-----EHLASKEVEV 768

Query: 298 TDRETEIWKE-LQMTRGALLRSEEELRQSRAEKD-SFLNSLSR--IAQGEGTESFQDKMA 353
              E ++ +E   MT   + RS  E  QS  E + S L S  +  + + E   S   ++ 
Sbjct: 769 AKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR 828

Query: 354 TELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSY 413
           +E+   +++   +Q  +  + +    + Q   Q + +LA ++   +     +   KD   
Sbjct: 829 SEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLE-EDKDKKI 887

Query: 414 PELQTEILDLHLQVETLSR 432
            E+  E+  L   + +LS+
Sbjct: 888 NEMSKEVTKLKEALNSLSQ 906



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 43/180 (23%), Positives = 81/180 (45%), Gaps = 20/180 (11%)

Query: 85  LDRDTMIKKIERLQKENS--ILQH----KVDETSKKENEEPPCH---PVQSGSYNYQVLN 135
           L+  T +K++   QKENS  I +H        T+ KE EE   +    + S       L 
Sbjct: 713 LNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLE 772

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           ++L +E+AA        +S E +     + ++ L  +LK++  E E   K H ++ Q+ +
Sbjct: 773 KQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKE---KVHSEVVQIRS 829

Query: 196 RLA-IERSHATVKVKELREQAETAE-----QVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
            ++ ++R    ++     ++ E  E     Q AQ  ++E K   E   +   E++K K +
Sbjct: 830 EVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAE--SSSKLEEDKDKKI 887


>AL590431-11|CAH71269.1|  284|Homo sapiens tropomyosin 3 protein.
          Length = 284

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 56/253 (22%), Positives = 108/253 (42%), Gaps = 20/253 (7%)

Query: 162 ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQV 221
           A A     E + K  + E    +KK K  E  +++     S A    +E  E AE     
Sbjct: 25  AEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY----SEALKDAQEKLELAEKKAAD 80

Query: 222 AQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDM 281
           A++ V+    R + ++ ++   ++  A A                 ++   +R+++  D 
Sbjct: 81  AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALK--DE 138

Query: 282 ERRRCLEYVPCKEN----EPTDRE-TEIWKELQMTRGALLRSEE--ELRQSRA-----EK 329
           E+   L+ +  KE     E  DR+  E+ ++L +  G L R+EE  EL +S+      E 
Sbjct: 139 EKME-LQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEEL 197

Query: 330 DSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYE 388
            +  N+L  + AQ E     +DK   E+     K+ + +   +    +   +E+T+   E
Sbjct: 198 KNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 257

Query: 389 NQLAALRLEVKRL 401
           ++L A +L+ K +
Sbjct: 258 DELYAQKLKYKAI 270



 Score = 38.7 bits (86), Expect = 0.046
 Identities = 31/160 (19%), Positives = 73/160 (45%), Gaps = 9/160 (5%)

Query: 92  KKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
           ++++R Q+  +    K++E  K  +E E     +++ +   +   E++  +    +  K 
Sbjct: 97  EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE---EKMELQEIQLKEAKH 153

Query: 151 VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ----LVNRLAIERSHATV 206
           +   A+        ++  +E  L+ T+   E+A+ K  +LE+    + N L    + A  
Sbjct: 154 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAE- 212

Query: 207 KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKS 246
           K  +  ++ E   ++   ++ E + R EF +  VA+ EK+
Sbjct: 213 KYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKT 252



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 30/160 (18%), Positives = 76/160 (47%), Gaps = 7/160 (4%)

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           +E ++K+  +L  K+D+ +  +  E      +      + L +EL+  +   +  ++ + 
Sbjct: 1   MEAIKKKMQML--KLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELD 58

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
                L+ A+ ++   E++  D +AE     ++ + +E+ ++R     + A  K++E  +
Sbjct: 59  KYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 118

Query: 214 QAETAE---QVAQSRV--SEQKARTEFLQAKVAEQEKSKA 248
            A+ +E   +V ++R    E+K   + +Q K A+    +A
Sbjct: 119 AADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEA 158



 Score = 31.1 bits (67), Expect = 9.2
 Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 16/127 (12%)

Query: 346 ESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN-Y 404
           E+ + KM    LD+E  + + +Q   EQ++ E+  +    Q E++LAA++ ++K   +  
Sbjct: 2   EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSK----QLEDELAAMQKKLKGTEDEL 57

Query: 405 DCYSKDVSYPELQTEI-----LDLHLQVETLSRERTALITAAASRALMLERHERAADLFA 459
           D YS+ +   + + E+      D   +V +L+R R  L+     RA      ER A    
Sbjct: 58  DKYSEALKDAQEKLELAEKKAADAEAEVASLNR-RIQLVEEELDRA-----QERLATALQ 111

Query: 460 RMVRARK 466
           ++  A K
Sbjct: 112 KLEEAEK 118


>AL031428-1|CAI19705.1| 1026|Homo sapiens leucine zipper protein 1
           protein.
          Length = 1026

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 61/318 (19%), Positives = 137/318 (43%), Gaps = 26/318 (8%)

Query: 93  KIERLQKENSILQHKVDETSKKENE--EPPCHPVQSGSYNYQVLNE-ELSKERAAR-EAL 148
           K++ L +    L+       K E+E  +     +Q+   N  +L E E+ ++R  R E  
Sbjct: 19  KLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGK 78

Query: 149 KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
            E +  AE + R+ + ++   E   ++ K+E E  +K+  +LE+L    +  ++  T   
Sbjct: 79  DEEIKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLC 138

Query: 209 KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL 268
             L E+    ++++        +  E L+ KV E E S+                   +L
Sbjct: 139 LSLNEERNLTKKIS--------SELEMLRVKVKELESSE-------DRLDKTEQSLASEL 183

Query: 269 QSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE--TEIWKELQMTRGALLRSEEELRQSR 326
           +  +  ++  V  ER+   E    KENE   +E   ++ +  +M R     +    R   
Sbjct: 184 EKLKSLTLSFVS-ERKYLNEKE--KENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDL 240

Query: 327 AEKDSFLNSL-SRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT 385
             +D   ++L S+ ++ +G   +  ++  E  ++ +      Q  ++ ++  + +E+  T
Sbjct: 241 RIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKT 300

Query: 386 QYENQLAALRLEVKRLRN 403
           Q ++   +L  E+K++++
Sbjct: 301 QIKH-FESLEEELKKMKS 317



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 38/191 (19%), Positives = 83/191 (43%), Gaps = 5/191 (2%)

Query: 45  KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSIL 104
           K  N ++  +   L R    I + + + +  S E  +   LD    ++   R + EN   
Sbjct: 222 KKMNRDYTRNASNLERNDLRIEDGISSTLP-SKESRRKGGLDYLKQVENETRNKSENEKN 280

Query: 105 QHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARA 164
           +++ D   K  N+E     +++   +++ L EEL K ++    L++   S ++  ++  +
Sbjct: 281 RNQEDNKVKDLNQE--IEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLAS 338

Query: 165 RIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQS 224
           ++  ++ Q+K  K E E  + + +D   L ++   ER+       E      TA +++  
Sbjct: 339 QLEEIKLQIKKQK-ELENGEVEGED-AFLSSKGRHERTKFRGHGSEASVSKHTARELSPQ 396

Query: 225 RVSEQKARTEF 235
              E+    EF
Sbjct: 397 HKRERLRNREF 407


>AJ132949-1|CAB36967.1|  585|Homo sapiens rfg5 protein protein.
          Length = 585

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 70/369 (18%), Positives = 146/369 (39%), Gaps = 33/369 (8%)

Query: 95  ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
           E   KEN        + +   N++   H + +     Q+L  E+        +L +    
Sbjct: 195 EESSKENVSSNAACPDHTPTPNDDGKSHELSNLRLENQLLRNEVQSLNQEMASLLQRSKE 254

Query: 155 AESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSH-ATVKVK---- 209
            +  L  ARAR+   E+   D      + +     ++ L   +A + S  A +KV+    
Sbjct: 255 TQEELNKARARV---EKWNADHSKSDRMTRGLRAQVDDLTEAVAAKDSQLAVLKVRLQEA 311

Query: 210 ----ELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXX 265
                 R +A  A Q  +SR+ + ++    LQ +  +  + +                  
Sbjct: 312 DQLLSTRTEALEALQSEKSRIMQDQSEGNSLQNQALQTLQERL---HEADATLKREQESY 368

Query: 266 XQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD---RETEIWKELQMTRGALLRSEEEL 322
            Q+QS     +  V+MER+   E +   E + +D   R  E+ +++++ +  L  S++EL
Sbjct: 369 KQMQSEFAARLNKVEMERQNLAEAITLAERKYSDEKKRVDELQQQVKLYKLNLESSKQEL 428

Query: 323 RQSRAEKDSFLNS----LSRIAQGEGTESFQDKMATEL------LDREQKIVKLQQTIDE 372
              + +    L S    ++ + +G G E      A+ +       ++E +  ++Q+ + +
Sbjct: 429 IDYKQKATRILQSKEKLINSLKEGSGFEGLDSSTASSMELEELRHEKEMQREEIQKLMGQ 488

Query: 373 QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEI----LDLHLQVE 428
             +    ++    Q  N+  + R +++ L +     K  S  EL+TE+     + H   E
Sbjct: 489 IHQLRSELQDMEAQQVNEAESAREQLQDLHDQIAGQK-ASKQELETELERLKQEFHYIEE 547

Query: 429 TLSRERTAL 437
            L R +  L
Sbjct: 548 DLYRTKNTL 556



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 50/223 (22%), Positives = 97/223 (43%), Gaps = 22/223 (9%)

Query: 9   QNSLL--EHYAILRDMESRAGVAAETLGEV-RVLSNLE-WKTRNTEFDNDTERLHRMVAG 64
           +N LL  E  ++ ++M S    + ET  E+ +  + +E W   +++ D  T  L   V  
Sbjct: 230 ENQLLRNEVQSLNQEMASLLQRSKETQEELNKARARVEKWNADHSKSDRMTRGLRAQVDD 289

Query: 65  IAENLKAKINFSLEIAKIPWLDRDTMI----KKIERLQKENSILQHKVDETSKKENE--- 117
           + E + AK +  L + K+   + D ++    + +E LQ E S +     E +  +N+   
Sbjct: 290 LTEAVAAK-DSQLAVLKVRLQEADQLLSTRTEALEALQSEKSRIMQDQSEGNSLQNQALQ 348

Query: 118 --EPPCHPVQSG----SYNYQVLNEE----LSKERAAREALKEVVASAESMLRVARARIA 167
             +   H   +       +Y+ +  E    L+K    R+ L E +  AE      + R+ 
Sbjct: 349 TLQERLHEADATLKREQESYKQMQSEFAARLNKVEMERQNLAEAITLAERKYSDEKKRVD 408

Query: 168 TLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE 210
            L++Q+K  K   E +K++  D +Q   R+   +      +KE
Sbjct: 409 ELQQQVKLYKLNLESSKQELIDYKQKATRILQSKEKLINSLKE 451


>AF155135-1|AAF44722.1|  980|Homo sapiens novel retinal pigment
           epithelial cell protein protein.
          Length = 980

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 67/315 (21%), Positives = 132/315 (41%), Gaps = 41/315 (13%)

Query: 136 EELSKE-RAAREALKEVVASAESM--------LRVARARIATLERQLKDTKAEFEIAKKK 186
           EE  KE  + ++ +K  + S ESM        LRV    I  L++ L++   E E  K+K
Sbjct: 493 EEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEK 552

Query: 187 HKDLEQLVNRLAIERSHATV---KVKELREQAETAEQVAQSRVSE--------QKARTEF 235
            ++LE+ +    +ER   TV    V+E  E   +   V ++   E        Q+A+ E 
Sbjct: 553 VRELEEKL----VEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEI 608

Query: 236 LQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL--------QSFRDRSIRLVDMERRRCL 287
           ++ K   + +    A                +L        Q +++    L D  +R+ L
Sbjct: 609 MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 668

Query: 288 EYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES 347
           E V  +     + E    K +Q+T  +  ++E+ L + +++    LN L+++ Q      
Sbjct: 669 EDVTAEYIHKAEHE----KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ---LVD 721

Query: 348 FQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV--KRLRNYD 405
            Q + +  + +  Q I  L+    E  E   ++++ +   E ++A L  ++  ++    D
Sbjct: 722 AQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTD 781

Query: 406 CYSKDVSYPELQTEI 420
                 SY +LQ+ +
Sbjct: 782 AMVPRSSYEKLQSSL 796



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 3/107 (2%)

Query: 142 RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
           R A + ++E +++ +  L      +A LE+QL + KA    A       E+L + L  E 
Sbjct: 741 RTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEV 800

Query: 202 SHATVKVKE-LREQAETAEQVAQ--SRVSEQKARTEFLQAKVAEQEK 245
           S    K+KE ++E+ +   +V Q  S VS+ K   E +Q  +  +E+
Sbjct: 801 SVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQ 847



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 71/379 (18%), Positives = 152/379 (40%), Gaps = 45/379 (11%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERA-- 143
           D    +++ ER +++   L+ K+ E  K    +PP    +    +Y  + E ++KE+A  
Sbjct: 538 DLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFL 597

Query: 144 ---AREALKEVVA---------------SAESMLRVARARIATLERQL-------KDTKA 178
               +EA +E++                 AE M       I  L +Q+       K+ +A
Sbjct: 598 FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQA 657

Query: 179 EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQA 238
           E E  +K+ K LE +      +  H  +       +A+  + +++ +    K   E  Q 
Sbjct: 658 ELEDYRKR-KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL 716

Query: 239 K-VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEP 297
           K + + +K  +V+                +++       ++ +++     E++  KE E 
Sbjct: 717 KQLVDAQKENSVSITEHLQVITTLRTAAKEMEE------KISNLK-----EHLASKEVEV 765

Query: 298 TDRETEIWKE-LQMTRGALLRSEEELRQSRAEKD-SFLNSLSR--IAQGEGTESFQDKMA 353
              E ++ +E   MT   + RS  E  QS  E + S L S  +  + + E   S   ++ 
Sbjct: 766 AKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR 825

Query: 354 TELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSY 413
           +E+   +++   +Q  +  + +    + Q   Q + +LA ++   +     +   KD   
Sbjct: 826 SEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLE-EDKDKKI 884

Query: 414 PELQTEILDLHLQVETLSR 432
            E+  E+  L   + +LS+
Sbjct: 885 NEMSKEVTKLKEALNSLSQ 903



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 43/180 (23%), Positives = 81/180 (45%), Gaps = 20/180 (11%)

Query: 85  LDRDTMIKKIERLQKENS--ILQH----KVDETSKKENEEPPCH---PVQSGSYNYQVLN 135
           L+  T +K++   QKENS  I +H        T+ KE EE   +    + S       L 
Sbjct: 710 LNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLE 769

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           ++L +E+AA        +S E +     + ++ L  +LK++  E E   K H ++ Q+ +
Sbjct: 770 KQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKE---KVHSEVVQIRS 826

Query: 196 RLA-IERSHATVKVKELREQAETAE-----QVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
            ++ ++R    ++     ++ E  E     Q AQ  ++E K   E   +   E++K K +
Sbjct: 827 EVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAE--SSSKLEEDKDKKI 884


>AB037755-1|BAA92572.1|  989|Homo sapiens KIAA1334 protein protein.
          Length = 989

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 67/315 (21%), Positives = 132/315 (41%), Gaps = 41/315 (13%)

Query: 136 EELSKE-RAAREALKEVVASAESM--------LRVARARIATLERQLKDTKAEFEIAKKK 186
           EE  KE  + ++ +K  + S ESM        LRV    I  L++ L++   E E  K+K
Sbjct: 502 EEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEK 561

Query: 187 HKDLEQLVNRLAIERSHATV---KVKELREQAETAEQVAQSRVSE--------QKARTEF 235
            ++LE+ +    +ER   TV    V+E  E   +   V ++   E        Q+A+ E 
Sbjct: 562 VRELEEKL----VEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEI 617

Query: 236 LQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQL--------QSFRDRSIRLVDMERRRCL 287
           ++ K   + +    A                +L        Q +++    L D  +R+ L
Sbjct: 618 MKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSL 677

Query: 288 EYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTES 347
           E V  +     + E    K +Q+T  +  ++E+ L + +++    LN L+++ Q      
Sbjct: 678 EDVTAEYIHKAEHE----KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ---LVD 730

Query: 348 FQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV--KRLRNYD 405
            Q + +  + +  Q I  L+    E  E   ++++ +   E ++A L  ++  ++    D
Sbjct: 731 AQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTD 790

Query: 406 CYSKDVSYPELQTEI 420
                 SY +LQ+ +
Sbjct: 791 AMVPRSSYEKLQSSL 805



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 3/107 (2%)

Query: 142 RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
           R A + ++E +++ +  L      +A LE+QL + KA    A       E+L + L  E 
Sbjct: 750 RTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEV 809

Query: 202 SHATVKVKE-LREQAETAEQVAQ--SRVSEQKARTEFLQAKVAEQEK 245
           S    K+KE ++E+ +   +V Q  S VS+ K   E +Q  +  +E+
Sbjct: 810 SVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQ 856



 Score = 33.5 bits (73), Expect = 1.7
 Identities = 43/180 (23%), Positives = 82/180 (45%), Gaps = 20/180 (11%)

Query: 85  LDRDTMIKKIERLQKENS--ILQH----KVDETSKKENEEPPCH---PVQSGSYNYQVLN 135
           L+  T +K++   QKENS  I +H        T+ KE EE   +    + S       L 
Sbjct: 719 LNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLE 778

Query: 136 EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
           ++L +E+AA        +S E +     + ++ L  +LK++  E E   K H ++ Q+ +
Sbjct: 779 KQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKE---KVHSEVVQIRS 835

Query: 196 RLA-IERSHATVKVKELREQAETAE-----QVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
            ++ ++R    ++     ++ E  E     Q AQ  ++E K  +E   +   E++K K +
Sbjct: 836 EVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSE--SSSKLEEDKDKKI 893



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 71/379 (18%), Positives = 152/379 (40%), Gaps = 45/379 (11%)

Query: 86  DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERA-- 143
           D    +++ ER +++   L+ K+ E  K    +PP    +    +Y  + E ++KE+A  
Sbjct: 547 DLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFL 606

Query: 144 ---AREALKEVVA---------------SAESMLRVARARIATLERQL-------KDTKA 178
               +EA +E++                 AE M       I  L +Q+       K+ +A
Sbjct: 607 FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQA 666

Query: 179 EFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQA 238
           E E  +K+ K LE +      +  H  +       +A+  + +++ +    K   E  Q 
Sbjct: 667 ELEDYRKR-KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL 725

Query: 239 K-VAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEP 297
           K + + +K  +V+                +++       ++ +++     E++  KE E 
Sbjct: 726 KQLVDAQKENSVSITEHLQVITTLRTAAKEMEE------KISNLK-----EHLASKEVEV 774

Query: 298 TDRETEIWKE-LQMTRGALLRSEEELRQSRAEKD-SFLNSLSR--IAQGEGTESFQDKMA 353
              E ++ +E   MT   + RS  E  QS  E + S L S  +  + + E   S   ++ 
Sbjct: 775 AKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIR 834

Query: 354 TELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSY 413
           +E+   +++   +Q  +  + +    + Q   Q + +LA ++   +     +   KD   
Sbjct: 835 SEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLE-EDKDKKI 893

Query: 414 PELQTEILDLHLQVETLSR 432
            E+  E+  L   + +LS+
Sbjct: 894 NEMSKEVTKLKEALNSLSQ 912


>M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.
          Length = 2871

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 76/411 (18%), Positives = 157/411 (38%), Gaps = 28/411 (6%)

Query: 41   NLEWKTRNTE--FDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQ 98
            NL W+   +E         + R+   + E    K  +  E+AK+     + M     + +
Sbjct: 1152 NLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYE 1211

Query: 99   KENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESM 158
             E +I +  + E S ++ ++         S N +   + LS+E   R+   E+V   +S+
Sbjct: 1212 TEINITKTTIKEISMQKEDD---------SKNLRNQLDRLSREN--RDLKDEIVRLNDSI 1260

Query: 159  LRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETA 218
            L+    R    E  L+      EI +KK + LE  + ++  +RS    + K+  E+A   
Sbjct: 1261 LQATEQRRRAEENALQQKACGSEIMQKK-QHLEIELKQVMQQRSEDNARHKQSLEEAAKT 1319

Query: 219  EQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRL 278
             Q     +   KA  +    +  E E   +                     +    +I  
Sbjct: 1320 IQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQ 1379

Query: 279  VDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSR 338
            + M++         + +  T     + +E++  +  L ++ E LR+   +      + S 
Sbjct: 1380 LTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSE 1439

Query: 339  IAQGEGTESFQDKMATELLDRE-----QKIVKLQQTIDEQRENEKSMEQTMTQYENQLAA 393
            ++Q +     + +  T++   E     Q +    +TI ++ +  + ++Q + +  N    
Sbjct: 1440 VSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC 1499

Query: 394  LRLEVKRLR--NYDCYSKDVSYPEL-------QTEILDLHLQVETLSRERT 435
            L  E  RL+   YD    + S  E        + E+  L +  E +S+ERT
Sbjct: 1500 LEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERT 1550



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 62/357 (17%), Positives = 142/357 (39%), Gaps = 20/357 (5%)

Query: 55   TERLHRMVAGIAENLKAKINFSLEIAKIPWL-DRDTMIKKIERLQKENSILQ---HKVDE 110
            TE   R    + +  K   + + EI ++  L D++T  +K   L+ EN+ LQ   + + +
Sbjct: 1459 TEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC--LEDENARLQRVQYDLQK 1516

Query: 111  TSKKENEEPPCHPVQSGSYN-YQVLNEELSKERAAREALKEVVASAESMLRVARARIATL 169
             +    E      VQ       ++  E +S+ER  ++       ++   L++ + ++   
Sbjct: 1517 ANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEE 1576

Query: 170  ERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQ 229
              +LK T +E    +KK   LE+ +  +        +K+  L +Q E A  V +    + 
Sbjct: 1577 LNRLKRTASEDSCKRKK---LEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDL 1633

Query: 230  KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
            + + + L   + E+++++                   + +S +   +R    ++      
Sbjct: 1634 RQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKA----- 1688

Query: 290  VPCKENEPTDRETEIWKELQMTRGAL---LRSEEELRQSRAEKDSFLNSLSRIAQGEGTE 346
            +  K     + + EI +   +T       L  EEELR  R E D      S     +   
Sbjct: 1689 IEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNAT 1748

Query: 347  SFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
              +  + ++L     + ++LQ  I++ +   +++ Q + +++ Q       ++  +N
Sbjct: 1749 ILE--LRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKN 1803



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 65/396 (16%), Positives = 172/396 (43%), Gaps = 23/396 (5%)

Query: 56   ERLHRMVAGIAENLKAKINFSLEIAKIPW-LDRDTMIKKIER--LQKENSILQHKVDETS 112
            ++L   + G+  +LK +   +++I  +   L++ +++KK     L+++  +L   + E  
Sbjct: 1592 KKLEEELEGMRRSLKEQ---AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQ 1648

Query: 113  KKENEEPPCHPVQSGSYNYQVLNEELSKERA--AREALKEVVASAESMLRVARARIATLE 170
            + + EE      +  +   Q+L E+ S ++A    E  ++ +      L  ++  I  L+
Sbjct: 1649 RTQ-EELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQ 1707

Query: 171  RQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA----TVKVKELREQAETAEQVA---Q 223
               ++   E  + +++ ++L    + L   RS A       + ELR Q + +       Q
Sbjct: 1708 SLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQ 1767

Query: 224  SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER 283
              +++ +   E L+ ++ + +K    A                + +S   + I++++ ++
Sbjct: 1768 GLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVK-IKVLEQDK 1826

Query: 284  RRC--LEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
             R   LE    +     + ET + + L+  +  +     + +   + K+  +  +   ++
Sbjct: 1827 ARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIE--SE 1884

Query: 342  GEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL 401
             E +E  ++ + +E+   + +I ++++    +R+ E S  +T +Q E + +  + E+ +L
Sbjct: 1885 REKSEREKNSLRSEIERLQAEIKRIEERC--RRKLEDSTRETQSQLETERSRYQREIDKL 1942

Query: 402  RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            R     S   +  E +  +    L  + L ++ TA+
Sbjct: 1943 RQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAM 1978


>J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplakin
           mRNA, 3' end. ).
          Length = 1752

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 76/411 (18%), Positives = 157/411 (38%), Gaps = 28/411 (6%)

Query: 41  NLEWKTRNTE--FDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQ 98
           NL W+   +E         + R+   + E    K  +  E+AK+     + M     + +
Sbjct: 33  NLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYE 92

Query: 99  KENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESM 158
            E +I +  + E S ++ ++         S N +   + LS+E   R+   E+V   +S+
Sbjct: 93  TEINITKTTIKEISMQKEDD---------SKNLRNQLDRLSREN--RDLKDEIVRLNDSI 141

Query: 159 LRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETA 218
           L+    R    E  L+      EI +KK + LE  + ++  +RS    + K+  E+A   
Sbjct: 142 LQATEQRRRAEENALQQKACGSEIMQKK-QHLEIELKQVMQQRSEDNARHKQSLEEAAKT 200

Query: 219 EQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRL 278
            Q     +   KA  +    +  E E   +                     +    +I  
Sbjct: 201 IQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQ 260

Query: 279 VDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSR 338
           + M++         + +  T     + +E++  +  L ++ E LR+   +      + S 
Sbjct: 261 LTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSE 320

Query: 339 IAQGEGTESFQDKMATELLDRE-----QKIVKLQQTIDEQRENEKSMEQTMTQYENQLAA 393
           ++Q +     + +  T++   E     Q +    +TI ++ +  + ++Q + +  N    
Sbjct: 321 VSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC 380

Query: 394 LRLEVKRLR--NYDCYSKDVSYPEL-------QTEILDLHLQVETLSRERT 435
           L  E  RL+   YD    + S  E        + E+  L +  E +S+ERT
Sbjct: 381 LEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERT 431



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 62/357 (17%), Positives = 142/357 (39%), Gaps = 20/357 (5%)

Query: 55  TERLHRMVAGIAENLKAKINFSLEIAKIPWL-DRDTMIKKIERLQKENSILQ---HKVDE 110
           TE   R    + +  K   + + EI ++  L D++T  +K   L+ EN+ LQ   + + +
Sbjct: 340 TEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC--LEDENARLQRVQYDLQK 397

Query: 111 TSKKENEEPPCHPVQSGSYN-YQVLNEELSKERAAREALKEVVASAESMLRVARARIATL 169
            +    E      VQ       ++  E +S+ER  ++       ++   L++ + ++   
Sbjct: 398 ANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEE 457

Query: 170 ERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQ 229
             +LK T +E    +KK   LE+ +  +        +K+  L +Q E A  V +    + 
Sbjct: 458 LNRLKRTASEDSCKRKK---LEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDL 514

Query: 230 KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
           + + + L   + E+++++                   + +S +   +R    ++      
Sbjct: 515 RQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKA----- 569

Query: 290 VPCKENEPTDRETEIWKELQMTRGAL---LRSEEELRQSRAEKDSFLNSLSRIAQGEGTE 346
           +  K     + + EI +   +T       L  EEELR  R E D      S     +   
Sbjct: 570 IEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNAT 629

Query: 347 SFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
             +  + ++L     + ++LQ  I++ +   +++ Q + +++ Q       ++  +N
Sbjct: 630 ILE--LRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKN 684



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 65/396 (16%), Positives = 172/396 (43%), Gaps = 23/396 (5%)

Query: 56  ERLHRMVAGIAENLKAKINFSLEIAKIPW-LDRDTMIKKIER--LQKENSILQHKVDETS 112
           ++L   + G+  +LK +   +++I  +   L++ +++KK     L+++  +L   + E  
Sbjct: 473 KKLEEELEGMRRSLKEQ---AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQ 529

Query: 113 KKENEEPPCHPVQSGSYNYQVLNEELSKERA--AREALKEVVASAESMLRVARARIATLE 170
           + + EE      +  +   Q+L E+ S ++A    E  ++ +      L  ++  I  L+
Sbjct: 530 RTQ-EELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQ 588

Query: 171 RQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA----TVKVKELREQAETAEQVA---Q 223
              ++   E  + +++ ++L    + L   RS A       + ELR Q + +       Q
Sbjct: 589 SLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQ 648

Query: 224 SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER 283
             +++ +   E L+ ++ + +K    A                + +S   + I++++ ++
Sbjct: 649 GLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVK-IKVLEQDK 707

Query: 284 RRC--LEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
            R   LE    +     + ET + + L+  +  +     + +   + K+  +  +   ++
Sbjct: 708 ARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIE--SE 765

Query: 342 GEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL 401
            E +E  ++ + +E+   + +I ++++    +R+ E S  +T +Q E + +  + E+ +L
Sbjct: 766 REKSEREKNSLRSEIERLQAEIKRIEERC--RRKLEDSTRETQSQLETERSRYQREIDKL 823

Query: 402 RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
           R     S   +  E +  +    L  + L ++ TA+
Sbjct: 824 RQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAM 859


>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
            smooth muscle protein.
          Length = 1938

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 68/320 (21%), Positives = 136/320 (42%), Gaps = 18/320 (5%)

Query: 88   DTMIKKIERLQK-ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            D + K  ER QK EN + + +   +   E +      +Q+ +  Y    E   +  A ++
Sbjct: 859  DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 918

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
             L+E++   E+ L     R   L+ + K    +    +++ ++ E    +L +E+  A  
Sbjct: 919  ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978

Query: 207  KVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            K+K+L ++    +        E+K    R   L   +AE+E+                  
Sbjct: 979  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
               +L+   ++S + ++  +R+          +  D + +I  EL+M    L + EEEL+
Sbjct: 1039 LEVRLKK-EEKSRQELEKLKRKLEGDASDFHEQIADLQAQI-AELKM---QLAKKEEELQ 1093

Query: 324  QSRAEKDSFL----NSLSRIAQGEG-TESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
             + A  D  +    N+L +I + EG     Q+ + +E   R  K  K ++ + E+ E  K
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR-NKAEKQKRDLGEELEALK 1152

Query: 379  S-MEQTM--TQYENQLAALR 395
            + +E T+  T  + +L A R
Sbjct: 1153 TELEDTLDSTATQQELRAKR 1172



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 61/236 (25%), Positives = 108/236 (45%), Gaps = 33/236 (13%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI-AKIPWLDRDTMIKKIERLQKE 100
            L+ +    E + + ER  R +A  A+         LE+ A      R+  IK++ +LQ +
Sbjct: 1594 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 1653

Query: 101  NSILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEELSK-ERAAREA------L 148
                Q ++++     +E     +      +S   +   L E+L+  ERA ++A      L
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713

Query: 149  KEVVASA-------ESMLRVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRL 197
             E +AS+       +   R   ARIA LE +L++ +   E      +K  +  EQL N L
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1773

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQK--ARTEF------LQAKVAEQEK 245
            A ERS A  K +  R+Q E   +  +S++ E +   +++F      L+AK+A+ E+
Sbjct: 1774 ATERSTAQ-KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 47/281 (16%), Positives = 120/281 (42%), Gaps = 14/281 (4%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EE+  +    +  KE    AE+ L+    + + L  +    + + +   + + + E++  
Sbjct: 852  EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTE---FLQAKVAEQEKSKAVAXX 252
            RLA ++      + E+  + E  E   Q   +E+K   +    L+ ++ E+E ++     
Sbjct: 912  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 971

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM-T 311
                          ++    D++ +L   ER+   E +        + E +     ++  
Sbjct: 972  EKVTAEAKIKKLEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030

Query: 312  RGALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            +   + SE E+R  + EK    L  L R  +G+ ++ F +++A    D + +I +L+  +
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIA----DLQAQIAELKMQL 1085

Query: 371  DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
                + E+ ++  + + ++++A     +K++R  + +  D+
Sbjct: 1086 ---AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1123



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 79/398 (19%), Positives = 155/398 (38%), Gaps = 36/398 (9%)

Query: 19   LRDMESRAGVAAETLGE-VRVLSNLEW--KTRNTEFDNDTERLHRMVAGIAENLKAKINF 75
            LR +E       + L E +    NLE    T N +  +  ++L    + +    + K  F
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397

Query: 76   SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEPPCHPVQSGSYNY-QV 133
              EI  +     +      ++L+K  + LQ ++D+     +N+      ++     + Q+
Sbjct: 1398 QKEIENLTQ-QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1456

Query: 134  LNEELS--------KERAAREALKEVVASAESMLRVARARIAT---LERQLKDTKAEFEI 182
            L EE +        ++RA  EA +E    A S+ R     +     LER  K  KAE E 
Sbjct: 1457 LAEEKNISSKYADERDRAEAEA-REKETKALSLARALEEALEAKEELERTNKMLKAEMED 1515

Query: 183  AKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVA 241
                  D+ + V+ L   +     +++E++ Q E  E   Q+   + K R E  +QA   
Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQA-TEDAKLRLEVNMQALKG 1574

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDR 300
            + E+                     QLQ    +    L D  ++R L     K+ E    
Sbjct: 1575 QFERD-------LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD-- 1625

Query: 301  ETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE 360
                 K+L++   + ++  EE  +   +  + +    R  + E   + +D++     + E
Sbjct: 1626 ----LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR--ELEDARASRDEIFATAKENE 1679

Query: 361  QKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +K   L+  + + +E+  + E+   Q + +   L  E+
Sbjct: 1680 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1717



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 39/185 (21%), Positives = 77/185 (41%), Gaps = 16/185 (8%)

Query: 307  ELQMTRGALLRSEEELR---QSRAEKDSFLNSLSRIAQGEG-----TESFQDKMATELLD 358
            ELQ T+    ++E EL+   Q  ++     N L    Q E       E  + ++A +  +
Sbjct: 860  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 919

Query: 359  REQKIVKLQQTIDEQREN-------EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
             E+ + +++  ++E+ +         K M Q M   E QL       ++L+  +  + + 
Sbjct: 920  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEA 978

Query: 412  SYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAAL 471
               +L+ EIL +  Q   LS+ER  L    +     L   E  A    ++    + + + 
Sbjct: 979  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038

Query: 472  LDGRI 476
            L+ R+
Sbjct: 1039 LEVRL 1043



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 75/385 (19%), Positives = 155/385 (40%), Gaps = 23/385 (5%)

Query: 35   EVRVLSN-LEWKTRNTEFDNDTERLHRMVAGIAENLKAKIN-FSLEIAKIPWLDRDTMIK 92
            EV VL   L+ +TR+ E     + + +  A   E L  ++  F    A +   ++ T+ K
Sbjct: 1175 EVTVLKKALDEETRSHEAQ--VQEMRQKHAQAVEELTEQLEQFKRAKANLD-KNKQTLEK 1231

Query: 93   KIERLQKENSIL-QHKVDETSKKENEEPPCHPVQS----GSYNYQVLNEELSKERAAREA 147
            +   L  E  +L Q K +   KK+  E     +QS    G      LN+++ K +   E+
Sbjct: 1232 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVES 1291

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +  ++  AE         +A+L  QL+DT+   +   ++  ++   + +L  ER+    +
Sbjct: 1292 VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQ 1351

Query: 208  VKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSK---AVAXXXXXXXXXXX 261
            + E  E  +  E+       ++S+ K + +   + V   E+ K                 
Sbjct: 1352 LDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEK 1411

Query: 262  XXXXXQLQSFRDRSIR-----LVDMERRRCLEYVPCKENEPTDRETEIWKELQMT-RGAL 315
                 +L+  ++R  +     +VD++ +R L     K+    D+     K +        
Sbjct: 1412 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1471

Query: 316  LRSEEELRQSRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
             R+E E R+   +  S   +L    +  E  E     +  E+ D       + + + E  
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1531

Query: 375  ENEKSMEQTMTQYENQLAALRLEVK 399
            ++++++E  M + + QL  L  E++
Sbjct: 1532 KSKRALETQMEEMKTQLEELEDELQ 1556



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 17/130 (13%)

Query: 135  NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA----KKKHKDL 190
            N+EL  +    E    V +  +S +    A+IA LE Q++    E + A    K+K K L
Sbjct: 1794 NKELRSKLHEMEGA--VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1851

Query: 191  EQLVNRLAIERSHA----------TVKVKELREQAETAEQVAQS-RVSEQKARTEFLQAK 239
            ++++ ++  ER  A            +VK+L+ Q E AE+ +Q    + +K + E  +A 
Sbjct: 1852 KEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEAT 1911

Query: 240  VAEQEKSKAV 249
             + +   + V
Sbjct: 1912 ESNEAMGREV 1921


>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
            smooth muscle protein.
          Length = 1938

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 68/320 (21%), Positives = 136/320 (42%), Gaps = 18/320 (5%)

Query: 88   DTMIKKIERLQK-ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            D + K  ER QK EN + + +   +   E +      +Q+ +  Y    E   +  A ++
Sbjct: 859  DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 918

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
             L+E++   E+ L     R   L+ + K    +    +++ ++ E    +L +E+  A  
Sbjct: 919  ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978

Query: 207  KVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            K+K+L ++    +        E+K    R   L   +AE+E+                  
Sbjct: 979  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
               +L+   ++S + ++  +R+          +  D + +I  EL+M    L + EEEL+
Sbjct: 1039 LEVRLKK-EEKSRQELEKLKRKLEGDASDFHEQIADLQAQI-AELKM---QLAKKEEELQ 1093

Query: 324  QSRAEKDSFL----NSLSRIAQGEG-TESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
             + A  D  +    N+L +I + EG     Q+ + +E   R  K  K ++ + E+ E  K
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR-NKAEKQKRDLGEELEALK 1152

Query: 379  S-MEQTM--TQYENQLAALR 395
            + +E T+  T  + +L A R
Sbjct: 1153 TELEDTLDSTATQQELRAKR 1172



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 61/236 (25%), Positives = 108/236 (45%), Gaps = 33/236 (13%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI-AKIPWLDRDTMIKKIERLQKE 100
            L+ +    E + + ER  R +A  A+         LE+ A      R+  IK++ +LQ +
Sbjct: 1594 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 1653

Query: 101  NSILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEELSK-ERAAREA------L 148
                Q ++++     +E     +      +S   +   L E+L+  ERA ++A      L
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713

Query: 149  KEVVASA-------ESMLRVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRL 197
             E +AS+       +   R   ARIA LE +L++ +   E      +K  +  EQL N L
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1773

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQK--ARTEF------LQAKVAEQEK 245
            A ERS A  K +  R+Q E   +  +S++ E +   +++F      L+AK+A+ E+
Sbjct: 1774 ATERSTAQ-KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 47/281 (16%), Positives = 120/281 (42%), Gaps = 14/281 (4%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EE+  +    +  KE    AE+ L+    + + L  +    + + +   + + + E++  
Sbjct: 852  EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTE---FLQAKVAEQEKSKAVAXX 252
            RLA ++      + E+  + E  E   Q   +E+K   +    L+ ++ E+E ++     
Sbjct: 912  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 971

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM-T 311
                          ++    D++ +L   ER+   E +        + E +     ++  
Sbjct: 972  EKVTAEAKIKKLEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030

Query: 312  RGALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            +   + SE E+R  + EK    L  L R  +G+ ++ F +++A    D + +I +L+  +
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIA----DLQAQIAELKMQL 1085

Query: 371  DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
                + E+ ++  + + ++++A     +K++R  + +  D+
Sbjct: 1086 ---AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1123



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 79/398 (19%), Positives = 155/398 (38%), Gaps = 36/398 (9%)

Query: 19   LRDMESRAGVAAETLGE-VRVLSNLEW--KTRNTEFDNDTERLHRMVAGIAENLKAKINF 75
            LR +E       + L E +    NLE    T N +  +  ++L    + +    + K  F
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397

Query: 76   SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEPPCHPVQSGSYNY-QV 133
              EI  +     +      ++L+K  + LQ ++D+     +N+      ++     + Q+
Sbjct: 1398 QKEIENLTQ-QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1456

Query: 134  LNEELS--------KERAAREALKEVVASAESMLRVARARIAT---LERQLKDTKAEFEI 182
            L EE +        ++RA  EA +E    A S+ R     +     LER  K  KAE E 
Sbjct: 1457 LAEEKNISSKYADERDRAEAEA-REKETKALSLARALEEALEAKEELERTNKMLKAEMED 1515

Query: 183  AKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVA 241
                  D+ + V+ L   +     +++E++ Q E  E   Q+   + K R E  +QA   
Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQA-TEDAKLRLEVNMQALKG 1574

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDR 300
            + E+                     QLQ    +    L D  ++R L     K+ E    
Sbjct: 1575 QFERD-------LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD-- 1625

Query: 301  ETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE 360
                 K+L++   + ++  EE  +   +  + +    R  + E   + +D++     + E
Sbjct: 1626 ----LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR--ELEDARASRDEIFATAKENE 1679

Query: 361  QKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +K   L+  + + +E+  + E+   Q + +   L  E+
Sbjct: 1680 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1717



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 39/185 (21%), Positives = 77/185 (41%), Gaps = 16/185 (8%)

Query: 307  ELQMTRGALLRSEEELR---QSRAEKDSFLNSLSRIAQGEG-----TESFQDKMATELLD 358
            ELQ T+    ++E EL+   Q  ++     N L    Q E       E  + ++A +  +
Sbjct: 860  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 919

Query: 359  REQKIVKLQQTIDEQREN-------EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
             E+ + +++  ++E+ +         K M Q M   E QL       ++L+  +  + + 
Sbjct: 920  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEA 978

Query: 412  SYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAAL 471
               +L+ EIL +  Q   LS+ER  L    +     L   E  A    ++    + + + 
Sbjct: 979  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038

Query: 472  LDGRI 476
            L+ R+
Sbjct: 1039 LEVRL 1043



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 75/385 (19%), Positives = 155/385 (40%), Gaps = 23/385 (5%)

Query: 35   EVRVLSN-LEWKTRNTEFDNDTERLHRMVAGIAENLKAKIN-FSLEIAKIPWLDRDTMIK 92
            EV VL   L+ +TR+ E     + + +  A   E L  ++  F    A +   ++ T+ K
Sbjct: 1175 EVTVLKKALDEETRSHEAQ--VQEMRQKHAQAVEELTEQLEQFKRAKANLD-KNKQTLEK 1231

Query: 93   KIERLQKENSIL-QHKVDETSKKENEEPPCHPVQS----GSYNYQVLNEELSKERAAREA 147
            +   L  E  +L Q K +   KK+  E     +QS    G      LN+++ K +   E+
Sbjct: 1232 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVES 1291

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +  ++  AE         +A+L  QL+DT+   +   ++  ++   + +L  ER+    +
Sbjct: 1292 VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQ 1351

Query: 208  VKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSK---AVAXXXXXXXXXXX 261
            + E  E  +  E+       ++S+ K + +   + V   E+ K                 
Sbjct: 1352 LDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEK 1411

Query: 262  XXXXXQLQSFRDRSIR-----LVDMERRRCLEYVPCKENEPTDRETEIWKELQMT-RGAL 315
                 +L+  ++R  +     +VD++ +R L     K+    D+     K +        
Sbjct: 1412 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1471

Query: 316  LRSEEELRQSRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
             R+E E R+   +  S   +L    +  E  E     +  E+ D       + + + E  
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1531

Query: 375  ENEKSMEQTMTQYENQLAALRLEVK 399
            ++++++E  M + + QL  L  E++
Sbjct: 1532 KSKRALETQMEEMKTQLEELEDELQ 1556



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 17/130 (13%)

Query: 135  NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA----KKKHKDL 190
            N+EL  +    E    V +  +S +    A+IA LE Q++    E + A    K+K K L
Sbjct: 1794 NKELRSKLHEMEGA--VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1851

Query: 191  EQLVNRLAIERSHA----------TVKVKELREQAETAEQVAQS-RVSEQKARTEFLQAK 239
            ++++ ++  ER  A            +VK+L+ Q E AE+ +Q    + +K + E  +A 
Sbjct: 1852 KEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEAT 1911

Query: 240  VAEQEKSKAV 249
             + +   + V
Sbjct: 1912 ESNEAMGREV 1921


>BC023566-1|AAH23566.1|  740|Homo sapiens RAS and EF-hand domain
           containing protein.
          Length = 740

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 26/116 (22%), Positives = 58/116 (50%), Gaps = 4/116 (3%)

Query: 322 LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME 381
           +R+ R +     N    + + +   + Q     E +D+  +  + +   DE+R+ E+++ 
Sbjct: 174 IREIRLQSTEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALS 233

Query: 382 QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE----LQTEILDLHLQVETLSRE 433
               QYE ++  L++ +K+LR  +  SK VS  E    L+ +I DL ++ + + ++
Sbjct: 234 DLRRQYETEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKD 289


>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
          Length = 2069

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 69/401 (17%), Positives = 170/401 (42%), Gaps = 28/401 (6%)

Query: 88  DTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA 147
           ++++  ++   K +S+ +  + ++ + ++ +  CH ++           E+    + +E 
Sbjct: 432 ESVVSGLDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEV 491

Query: 148 LKEVVASAESMLRVARARIATLERQLKDT--KAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
             +   +  S+L    A   T    LK +  +A  E++++  K L QL++ +  E+S   
Sbjct: 492 ELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKAL-QLLHDIR-EQSRKL 549

Query: 206 VKVKELREQAETAE------QVAQSRVSEQKARTEFLQAKVAEQ----EKSKAVAXXXXX 255
            ++KE   QA+  E      Q+ +  VS ++ R++  ++++ E     E+ K  A     
Sbjct: 550 QEIKEQEYQAQVEEMRLMMNQLEEDLVSARR-RSDLYESELRESRLAAEEFKRKATECQH 608

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGAL 315
                      ++  +    +  ++ E++  ++ +  K  +     TE  + LQ  R A 
Sbjct: 609 KLLKAKDQGKPEVGEYA--KLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAK 666

Query: 316 LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRE 375
            R+E EL + +  +DS      ++ + E      +     L   E++  +L+  I  + +
Sbjct: 667 ERAERELEKLQNREDSSEGIRKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSQ 726

Query: 376 NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERT 435
             + M   + + E +    ++  + L  +    K+  Y E + ++LD  ++ +   +E  
Sbjct: 727 QIQQMADKILELEEKHREAQVSAQHLEVH-LKQKEQHYEE-KIKVLDNQIKKDLADKE-- 782

Query: 436 ALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRI 476
                  +   M++RHE  A    +++  +K +   +D +I
Sbjct: 783 -------TLENMMQRHEEEAHEKGKILSEQKAMINAMDSKI 816



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 46/208 (22%), Positives = 87/208 (41%), Gaps = 25/208 (12%)

Query: 40   SNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK 99
            S  E + R  +   DTE+  R  A        +I  S ++ ++   +    I  +++  K
Sbjct: 1097 SQFECRVRELQRMLDTEKQSRARAD------QRITESRQVVELAVKEHKAEILALQQALK 1150

Query: 100  ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML 159
            E  +   K +  S K N+    H +     N + L ++L  ER  ++ L E  A  +  +
Sbjct: 1151 EQKL---KAESLSDKLNDLEKKHAMLE--MNARSLQQKLETERELKQRLLEEQAKLQQQM 1205

Query: 160  RVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE 219
             + +  I  L + L++     ++ K +  DLE  +  + +  SH  VK+           
Sbjct: 1206 DLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKM----------- 1254

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSK 247
               +  +S+Q    +FLQAK+ +  K K
Sbjct: 1255 ---EGTISQQTKLIDFLQAKMDQPAKKK 1279



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 65/339 (19%), Positives = 122/339 (35%), Gaps = 21/339 (6%)

Query: 124  VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            V+    N    N  L  +R  + A +E+++           +   LE Q  + K E ++ 
Sbjct: 824  VELSEANKLAANSSLFTQRNMK-AQEEMISELRQQKFYLETQAGKLEAQ--NRKLEEQLE 880

Query: 184  KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF--LQAKVA 241
            K  H+D       L +E     V ++   ++ E   Q+ + ++S Q+  ++   LQA  A
Sbjct: 881  KISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARA 940

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
              E     A                 L + RD   R  D  R  C      +E    ++ 
Sbjct: 941  ALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQ--LNQL 998

Query: 302  TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
            TE   EL      L    ++L ++    D  +   S +          D +  E+ +RE 
Sbjct: 999  TEDNAELNNQNFYL---SKQLDEASGANDEIVQLRSEV----------DHLRREITEREM 1045

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNY-DCYSKDVSYPELQTEI 420
            ++   +QT++  +     +E+ +   E     L  + ++   +      + S  E +   
Sbjct: 1046 QLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRE 1105

Query: 421  LDLHLQVETLSRERTALITAAASRALMLERHERAADLFA 459
            L   L  E  SR R       + + + L   E  A++ A
Sbjct: 1106 LQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILA 1144



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 59/271 (21%), Positives = 116/271 (42%), Gaps = 26/271 (9%)

Query: 152  VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
            + S +  +   +     LE Q+ D +A  +   +K +  E   + L  E+S    +V+EL
Sbjct: 1047 LTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVREL 1106

Query: 212  REQAETAEQ--------VAQSR------VSEQKARTEFLQAKVAEQE-KSKAVA------ 250
            +   +T +Q        + +SR      V E KA    LQ  + EQ+ K+++++      
Sbjct: 1107 QRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDL 1166

Query: 251  XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM 310
                            +L++ R+   RL++ E+ +  + +  ++N    R T+  +E  +
Sbjct: 1167 EKKHAMLEMNARSLQQKLETERELKQRLLE-EQAKLQQQMDLQKNH-IFRLTQGLQE-AL 1223

Query: 311  TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
             R  LL++E    + + E    L S  ++   EGT S Q K+   L  +  +  K ++ +
Sbjct: 1224 DRADLLKTERSDLEYQLENIQVLYSHEKVKM-EGTISQQTKLIDFLQAKMDQPAKKKKGL 1282

Query: 371  DEQRENEKSM-EQTMTQYENQLAALRLEVKR 400
              +R+ + ++  Q   QY     AL  E  R
Sbjct: 1283 FSRRKEDPALPTQVPLQYNELKLALEKEKAR 1313


>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
            chain isoform SM2 protein.
          Length = 1945

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 68/320 (21%), Positives = 136/320 (42%), Gaps = 18/320 (5%)

Query: 88   DTMIKKIERLQK-ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            D + K  ER QK EN + + +   +   E +      +Q+ +  Y    E   +  A ++
Sbjct: 866  DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 925

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
             L+E++   E+ L     R   L+ + K    +    +++ ++ E    +L +E+  A  
Sbjct: 926  ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 985

Query: 207  KVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            K+K+L ++    +        E+K    R   L   +AE+E+                  
Sbjct: 986  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
               +L+   ++S + ++  +R+          +  D + +I  EL+M    L + EEEL+
Sbjct: 1046 LEVRLKK-EEKSRQELEKLKRKLEGDASDFHEQIADLQAQI-AELKM---QLAKKEEELQ 1100

Query: 324  QSRAEKDSFL----NSLSRIAQGEG-TESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
             + A  D  +    N+L +I + EG     Q+ + +E   R  K  K ++ + E+ E  K
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR-NKAEKQKRDLGEELEALK 1159

Query: 379  S-MEQTM--TQYENQLAALR 395
            + +E T+  T  + +L A R
Sbjct: 1160 TELEDTLDSTATQQELRAKR 1179



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 61/236 (25%), Positives = 108/236 (45%), Gaps = 33/236 (13%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI-AKIPWLDRDTMIKKIERLQKE 100
            L+ +    E + + ER  R +A  A+         LE+ A      R+  IK++ +LQ +
Sbjct: 1601 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 1660

Query: 101  NSILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEELSK-ERAAREA------L 148
                Q ++++     +E     +      +S   +   L E+L+  ERA ++A      L
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720

Query: 149  KEVVASA-------ESMLRVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRL 197
             E +AS+       +   R   ARIA LE +L++ +   E      +K  +  EQL N L
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1780

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQK--ARTEF------LQAKVAEQEK 245
            A ERS A  K +  R+Q E   +  +S++ E +   +++F      L+AK+A+ E+
Sbjct: 1781 ATERSTAQ-KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 47/281 (16%), Positives = 120/281 (42%), Gaps = 14/281 (4%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EE+  +    +  KE    AE+ L+    + + L  +    + + +   + + + E++  
Sbjct: 859  EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTE---FLQAKVAEQEKSKAVAXX 252
            RLA ++      + E+  + E  E   Q   +E+K   +    L+ ++ E+E ++     
Sbjct: 919  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 978

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM-T 311
                          ++    D++ +L   ER+   E +        + E +     ++  
Sbjct: 979  EKVTAEAKIKKLEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037

Query: 312  RGALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            +   + SE E+R  + EK    L  L R  +G+ ++ F +++A    D + +I +L+  +
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIA----DLQAQIAELKMQL 1092

Query: 371  DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
                + E+ ++  + + ++++A     +K++R  + +  D+
Sbjct: 1093 ---AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1130



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 79/398 (19%), Positives = 155/398 (38%), Gaps = 36/398 (9%)

Query: 19   LRDMESRAGVAAETLGE-VRVLSNLEW--KTRNTEFDNDTERLHRMVAGIAENLKAKINF 75
            LR +E       + L E +    NLE    T N +  +  ++L    + +    + K  F
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404

Query: 76   SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEPPCHPVQSGSYNY-QV 133
              EI  +     +      ++L+K  + LQ ++D+     +N+      ++     + Q+
Sbjct: 1405 QKEIENLTQ-QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1463

Query: 134  LNEELS--------KERAAREALKEVVASAESMLRVARARIAT---LERQLKDTKAEFEI 182
            L EE +        ++RA  EA +E    A S+ R     +     LER  K  KAE E 
Sbjct: 1464 LAEEKNISSKYADERDRAEAEA-REKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522

Query: 183  AKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVA 241
                  D+ + V+ L   +     +++E++ Q E  E   Q+   + K R E  +QA   
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQA-TEDAKLRLEVNMQALKG 1581

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDR 300
            + E+                     QLQ    +    L D  ++R L     K+ E    
Sbjct: 1582 QFERD-------LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD-- 1632

Query: 301  ETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE 360
                 K+L++   + ++  EE  +   +  + +    R  + E   + +D++     + E
Sbjct: 1633 ----LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR--ELEDARASRDEIFATAKENE 1686

Query: 361  QKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +K   L+  + + +E+  + E+   Q + +   L  E+
Sbjct: 1687 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1724



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 39/185 (21%), Positives = 77/185 (41%), Gaps = 16/185 (8%)

Query: 307  ELQMTRGALLRSEEELR---QSRAEKDSFLNSLSRIAQGEG-----TESFQDKMATELLD 358
            ELQ T+    ++E EL+   Q  ++     N L    Q E       E  + ++A +  +
Sbjct: 867  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926

Query: 359  REQKIVKLQQTIDEQREN-------EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
             E+ + +++  ++E+ +         K M Q M   E QL       ++L+  +  + + 
Sbjct: 927  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEA 985

Query: 412  SYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAAL 471
               +L+ EIL +  Q   LS+ER  L    +     L   E  A    ++    + + + 
Sbjct: 986  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045

Query: 472  LDGRI 476
            L+ R+
Sbjct: 1046 LEVRL 1050



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 75/385 (19%), Positives = 155/385 (40%), Gaps = 23/385 (5%)

Query: 35   EVRVLSN-LEWKTRNTEFDNDTERLHRMVAGIAENLKAKIN-FSLEIAKIPWLDRDTMIK 92
            EV VL   L+ +TR+ E     + + +  A   E L  ++  F    A +   ++ T+ K
Sbjct: 1182 EVTVLKKALDEETRSHEAQ--VQEMRQKHAQAVEELTEQLEQFKRAKANLD-KNKQTLEK 1238

Query: 93   KIERLQKENSIL-QHKVDETSKKENEEPPCHPVQS----GSYNYQVLNEELSKERAAREA 147
            +   L  E  +L Q K +   KK+  E     +QS    G      LN+++ K +   E+
Sbjct: 1239 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVES 1298

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +  ++  AE         +A+L  QL+DT+   +   ++  ++   + +L  ER+    +
Sbjct: 1299 VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQ 1358

Query: 208  VKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSK---AVAXXXXXXXXXXX 261
            + E  E  +  E+       ++S+ K + +   + V   E+ K                 
Sbjct: 1359 LDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEK 1418

Query: 262  XXXXXQLQSFRDRSIR-----LVDMERRRCLEYVPCKENEPTDRETEIWKELQMT-RGAL 315
                 +L+  ++R  +     +VD++ +R L     K+    D+     K +        
Sbjct: 1419 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1478

Query: 316  LRSEEELRQSRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
             R+E E R+   +  S   +L    +  E  E     +  E+ D       + + + E  
Sbjct: 1479 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1538

Query: 375  ENEKSMEQTMTQYENQLAALRLEVK 399
            ++++++E  M + + QL  L  E++
Sbjct: 1539 KSKRALETQMEEMKTQLEELEDELQ 1563



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 17/130 (13%)

Query: 135  NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA----KKKHKDL 190
            N+EL  +    E    V +  +S +    A+IA LE Q++    E + A    K+K K L
Sbjct: 1801 NKELRSKLHEMEGA--VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1858

Query: 191  EQLVNRLAIERSHA----------TVKVKELREQAETAEQVAQS-RVSEQKARTEFLQAK 239
            ++++ ++  ER  A            +VK+L+ Q E AE+ +Q    + +K + E  +A 
Sbjct: 1859 KEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEAT 1918

Query: 240  VAEQEKSKAV 249
             + +   + V
Sbjct: 1919 ESNEAMGREV 1928


>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
            chain isoform SM1 protein.
          Length = 1979

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 68/320 (21%), Positives = 136/320 (42%), Gaps = 18/320 (5%)

Query: 88   DTMIKKIERLQK-ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            D + K  ER QK EN + + +   +   E +      +Q+ +  Y    E   +  A ++
Sbjct: 866  DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 925

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
             L+E++   E+ L     R   L+ + K    +    +++ ++ E    +L +E+  A  
Sbjct: 926  ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 985

Query: 207  KVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            K+K+L ++    +        E+K    R   L   +AE+E+                  
Sbjct: 986  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
               +L+   ++S + ++  +R+          +  D + +I  EL+M    L + EEEL+
Sbjct: 1046 LEVRLKK-EEKSRQELEKLKRKLEGDASDFHEQIADLQAQI-AELKM---QLAKKEEELQ 1100

Query: 324  QSRAEKDSFL----NSLSRIAQGEG-TESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
             + A  D  +    N+L +I + EG     Q+ + +E   R  K  K ++ + E+ E  K
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR-NKAEKQKRDLGEELEALK 1159

Query: 379  S-MEQTM--TQYENQLAALR 395
            + +E T+  T  + +L A R
Sbjct: 1160 TELEDTLDSTATQQELRAKR 1179



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 61/236 (25%), Positives = 108/236 (45%), Gaps = 33/236 (13%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI-AKIPWLDRDTMIKKIERLQKE 100
            L+ +    E + + ER  R +A  A+         LE+ A      R+  IK++ +LQ +
Sbjct: 1601 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 1660

Query: 101  NSILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEELSK-ERAAREA------L 148
                Q ++++     +E     +      +S   +   L E+L+  ERA ++A      L
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720

Query: 149  KEVVASA-------ESMLRVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRL 197
             E +AS+       +   R   ARIA LE +L++ +   E      +K  +  EQL N L
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1780

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQK--ARTEF------LQAKVAEQEK 245
            A ERS A  K +  R+Q E   +  +S++ E +   +++F      L+AK+A+ E+
Sbjct: 1781 ATERSTAQ-KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 47/281 (16%), Positives = 120/281 (42%), Gaps = 14/281 (4%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EE+  +    +  KE    AE+ L+    + + L  +    + + +   + + + E++  
Sbjct: 859  EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTE---FLQAKVAEQEKSKAVAXX 252
            RLA ++      + E+  + E  E   Q   +E+K   +    L+ ++ E+E ++     
Sbjct: 919  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 978

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM-T 311
                          ++    D++ +L   ER+   E +        + E +     ++  
Sbjct: 979  EKVTAEAKIKKLEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1037

Query: 312  RGALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            +   + SE E+R  + EK    L  L R  +G+ ++ F +++A    D + +I +L+  +
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIA----DLQAQIAELKMQL 1092

Query: 371  DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
                + E+ ++  + + ++++A     +K++R  + +  D+
Sbjct: 1093 ---AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1130



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 79/398 (19%), Positives = 155/398 (38%), Gaps = 36/398 (9%)

Query: 19   LRDMESRAGVAAETLGE-VRVLSNLEW--KTRNTEFDNDTERLHRMVAGIAENLKAKINF 75
            LR +E       + L E +    NLE    T N +  +  ++L    + +    + K  F
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404

Query: 76   SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEPPCHPVQSGSYNY-QV 133
              EI  +     +      ++L+K  + LQ ++D+     +N+      ++     + Q+
Sbjct: 1405 QKEIENLTQ-QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1463

Query: 134  LNEELS--------KERAAREALKEVVASAESMLRVARARIAT---LERQLKDTKAEFEI 182
            L EE +        ++RA  EA +E    A S+ R     +     LER  K  KAE E 
Sbjct: 1464 LAEEKNISSKYADERDRAEAEA-REKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522

Query: 183  AKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVA 241
                  D+ + V+ L   +     +++E++ Q E  E   Q+   + K R E  +QA   
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQA-TEDAKLRLEVNMQALKG 1581

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDR 300
            + E+                     QLQ    +    L D  ++R L     K+ E    
Sbjct: 1582 QFERD-------LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD-- 1632

Query: 301  ETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE 360
                 K+L++   + ++  EE  +   +  + +    R  + E   + +D++     + E
Sbjct: 1633 ----LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR--ELEDARASRDEIFATAKENE 1686

Query: 361  QKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +K   L+  + + +E+  + E+   Q + +   L  E+
Sbjct: 1687 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1724



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 39/185 (21%), Positives = 77/185 (41%), Gaps = 16/185 (8%)

Query: 307  ELQMTRGALLRSEEELR---QSRAEKDSFLNSLSRIAQGEG-----TESFQDKMATELLD 358
            ELQ T+    ++E EL+   Q  ++     N L    Q E       E  + ++A +  +
Sbjct: 867  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926

Query: 359  REQKIVKLQQTIDEQREN-------EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
             E+ + +++  ++E+ +         K M Q M   E QL       ++L+  +  + + 
Sbjct: 927  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEA 985

Query: 412  SYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAAL 471
               +L+ EIL +  Q   LS+ER  L    +     L   E  A    ++    + + + 
Sbjct: 986  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045

Query: 472  LDGRI 476
            L+ R+
Sbjct: 1046 LEVRL 1050



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 75/385 (19%), Positives = 155/385 (40%), Gaps = 23/385 (5%)

Query: 35   EVRVLSN-LEWKTRNTEFDNDTERLHRMVAGIAENLKAKIN-FSLEIAKIPWLDRDTMIK 92
            EV VL   L+ +TR+ E     + + +  A   E L  ++  F    A +   ++ T+ K
Sbjct: 1182 EVTVLKKALDEETRSHEAQ--VQEMRQKHAQAVEELTEQLEQFKRAKANLD-KNKQTLEK 1238

Query: 93   KIERLQKENSIL-QHKVDETSKKENEEPPCHPVQS----GSYNYQVLNEELSKERAAREA 147
            +   L  E  +L Q K +   KK+  E     +QS    G      LN+++ K +   E+
Sbjct: 1239 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVES 1298

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +  ++  AE         +A+L  QL+DT+   +   ++  ++   + +L  ER+    +
Sbjct: 1299 VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQ 1358

Query: 208  VKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSK---AVAXXXXXXXXXXX 261
            + E  E  +  E+       ++S+ K + +   + V   E+ K                 
Sbjct: 1359 LDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEK 1418

Query: 262  XXXXXQLQSFRDRSIR-----LVDMERRRCLEYVPCKENEPTDRETEIWKELQMT-RGAL 315
                 +L+  ++R  +     +VD++ +R L     K+    D+     K +        
Sbjct: 1419 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1478

Query: 316  LRSEEELRQSRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
             R+E E R+   +  S   +L    +  E  E     +  E+ D       + + + E  
Sbjct: 1479 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1538

Query: 375  ENEKSMEQTMTQYENQLAALRLEVK 399
            ++++++E  M + + QL  L  E++
Sbjct: 1539 KSKRALETQMEEMKTQLEELEDELQ 1563



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 17/130 (13%)

Query: 135  NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA----KKKHKDL 190
            N+EL  +    E    V +  +S +    A+IA LE Q++    E + A    K+K K L
Sbjct: 1801 NKELRSKLHEMEGA--VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1858

Query: 191  EQLVNRLAIERSHA----------TVKVKELREQAETAEQVAQS-RVSEQKARTEFLQAK 239
            ++++ ++  ER  A            +VK+L+ Q E AE+ +Q    + +K + E  +A 
Sbjct: 1859 KEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEAT 1918

Query: 240  VAEQEKSKAV 249
             + +   + V
Sbjct: 1919 ESNEAMGREV 1928


>AL499602-1|CAH70678.1|  740|Homo sapiens RAS and EF-hand domain
           containing protein.
          Length = 740

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 26/116 (22%), Positives = 58/116 (50%), Gaps = 4/116 (3%)

Query: 322 LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSME 381
           +R+ R +     N    + + +   + Q     E +D+  +  + +   DE+R+ E+++ 
Sbjct: 174 IREIRLQSTEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALS 233

Query: 382 QTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPE----LQTEILDLHLQVETLSRE 433
               QYE ++  L++ +K+LR  +  SK VS  E    L+ +I DL ++ + + ++
Sbjct: 234 DLRRQYETEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKD 289


>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
           containing 18 protein.
          Length = 1044

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 87/423 (20%), Positives = 167/423 (39%), Gaps = 36/423 (8%)

Query: 35  EVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKA---KINFSLEIAKIPWLDRDT-M 90
           E ++++      +N E + +    +  +  +  N+     KI  + E AK   L++   M
Sbjct: 334 EEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEM 393

Query: 91  IKKIERL--QKENSILQHKVDE-TSKKENEEPPC--HPVQSGSYNYQVLNEELSKERAAR 145
            K+IERL  Q E    Q K  E T     ++  C  H ++S          E+ KE   +
Sbjct: 394 EKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKK 453

Query: 146 -EALKEV----------VASAESMLRVARARIATLERQLKDTKAEFE-IAKKKHKDLEQL 193
            EALK +          V   +S L + +  +     QL+  K +FE   KKK +++  L
Sbjct: 454 DEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCL 513

Query: 194 VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              L I ++H+  +  E     +   Q  Q  + ++  R   L+    + EK  +     
Sbjct: 514 QKELKI-KNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQE 572

Query: 254 XXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRG 313
                        +++   + +    D++R++ +E         T R+ +I  E+   + 
Sbjct: 573 LQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELT------GTARQVKI--EMDQYKE 624

Query: 314 ALLRSEEE---LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            L + E+E   L++    K   L+ L  I     TE  +   A + L++ Q   + + T 
Sbjct: 625 ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELT- 683

Query: 371 DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            E  +  + +E  +     +L +   +++ LR+       +S  E  T I DL  ++   
Sbjct: 684 -EALQKREVLETELQNAHGELKSTLRQLQELRDV-LQKAQLSLEEKYTTIKDLTAELREC 741

Query: 431 SRE 433
             E
Sbjct: 742 KME 744



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 83/402 (20%), Positives = 165/402 (41%), Gaps = 42/402 (10%)

Query: 5   LIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAG 64
           L A QN + E    +R ++S   +  E L  V  L+ LE      +F+   ++    V  
Sbjct: 457 LKALQNQVSEETIKVRQLDSALEICKEEL--VLHLNQLEGNKE--KFEKQLKKKSEEVYC 512

Query: 65  IAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPV 124
           + + LK K N SL+       +++ +++    LQ++  +LQ +     + E+ +      
Sbjct: 513 LQKELKIK-NHSLQETS----EQNVILQ--HTLQQQQQMLQQETIRNGELEDTQTKLEKQ 565

Query: 125 QSGSYNYQVLNEELSKER-AAREALKEVVASAESMLRVA---RARIATLERQLKDTKAEF 180
            S       L +EL K+R ++ E L+++    ES    A   R ++  L    +  K E 
Sbjct: 566 VSK------LEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEM 619

Query: 181 EIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQ 237
           +  K++   +E+ +  L  +  +  + + +L    +Q +T  +   + V E +      +
Sbjct: 620 DQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE 679

Query: 238 AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEP 297
            ++ E  + + V                 QLQ  RD  ++   +      +Y   K+   
Sbjct: 680 TELTEALQKREVLETELQNAHGELKSTLRQLQELRD-VLQKAQLSLEE--KYTTIKDLTA 736

Query: 298 TDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELL 357
             RE ++  E++  +  LL  ++ L++   E         R AQ    +    +   E+ 
Sbjct: 737 ELRECKM--EIEDKKQELLEMDQALKERNWELKQ------RAAQVTHLDMTIREHRGEM- 787

Query: 358 DREQKIVKLQQTID----EQRENEKSMEQTMTQYENQLAALR 395
             EQKI+KL+ T++    E +E  K +E    + +N    LR
Sbjct: 788 --EQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLR 827



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 59/293 (20%), Positives = 130/293 (44%), Gaps = 34/293 (11%)

Query: 131 YQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDL 190
           +Q++ EEL  E+A+  +        ES +    +++ TLE+QL++    +     K+ +L
Sbjct: 298 FQLIQEELL-EKASNSS------KLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAEL 350

Query: 191 EQ-LVNRLAIERSHAT---VKVKELREQAETAEQVAQSRVSEQKARTEFLQAKV------ 240
           EQ L+ +    RS  T    + +++    E A+++   +  E + + E L+A++      
Sbjct: 351 EQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQ 410

Query: 241 -AEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD 299
             EQEK+ ++                  L   +   ++  +M++   L+ +  + +E T 
Sbjct: 411 FKEQEKTMSMLQQDIICKQHHLESLDRLLTESKG-EMKKENMKKDEALKALQNQVSEETI 469

Query: 300 RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATE---L 356
           +  ++   L++ +  L+     L Q    K+ F   L +  + E     Q ++  +   L
Sbjct: 470 KVRQLDSALEICKEELVL---HLNQLEGNKEKFEKQLKK--KSEEVYCLQKELKIKNHSL 524

Query: 357 LDREQKIVKLQQTIDEQRE-------NEKSMEQTMTQYENQLAALRLEVKRLR 402
            +  ++ V LQ T+ +Q++           +E T T+ E Q++ L  E+++ R
Sbjct: 525 QETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQR 577


>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
           containing 18 protein.
          Length = 1454

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 87/423 (20%), Positives = 167/423 (39%), Gaps = 36/423 (8%)

Query: 35  EVRVLSNLEWKTRNTEFDNDTERLHRMVAGIAENLKA---KINFSLEIAKIPWLDRDT-M 90
           E ++++      +N E + +    +  +  +  N+     KI  + E AK   L++   M
Sbjct: 588 EEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEM 647

Query: 91  IKKIERL--QKENSILQHKVDE-TSKKENEEPPC--HPVQSGSYNYQVLNEELSKERAAR 145
            K+IERL  Q E    Q K  E T     ++  C  H ++S          E+ KE   +
Sbjct: 648 EKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKK 707

Query: 146 -EALKEV----------VASAESMLRVARARIATLERQLKDTKAEFE-IAKKKHKDLEQL 193
            EALK +          V   +S L + +  +     QL+  K +FE   KKK +++  L
Sbjct: 708 DEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCL 767

Query: 194 VNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXX 253
              L I ++H+  +  E     +   Q  Q  + ++  R   L+    + EK  +     
Sbjct: 768 QKELKI-KNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQE 826

Query: 254 XXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRG 313
                        +++   + +    D++R++ +E         T R+ +I  E+   + 
Sbjct: 827 LQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELT------GTARQVKI--EMDQYKE 878

Query: 314 ALLRSEEE---LRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            L + E+E   L++    K   L+ L  I     TE  +   A + L++ Q   + + T 
Sbjct: 879 ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELT- 937

Query: 371 DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETL 430
            E  +  + +E  +     +L +   +++ LR+       +S  E  T I DL  ++   
Sbjct: 938 -EALQKREVLETELQNAHGELKSTLRQLQELRDV-LQKAQLSLEEKYTTIKDLTAELREC 995

Query: 431 SRE 433
             E
Sbjct: 996 KME 998



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 83/402 (20%), Positives = 165/402 (41%), Gaps = 42/402 (10%)

Query: 5    LIAQQNSLLEHYAILRDMESRAGVAAETLGEVRVLSNLEWKTRNTEFDNDTERLHRMVAG 64
            L A QN + E    +R ++S   +  E L  V  L+ LE      +F+   ++    V  
Sbjct: 711  LKALQNQVSEETIKVRQLDSALEICKEEL--VLHLNQLEGNKE--KFEKQLKKKSEEVYC 766

Query: 65   IAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPV 124
            + + LK K N SL+       +++ +++    LQ++  +LQ +     + E+ +      
Sbjct: 767  LQKELKIK-NHSLQETS----EQNVILQ--HTLQQQQQMLQQETIRNGELEDTQTKLEKQ 819

Query: 125  QSGSYNYQVLNEELSKER-AAREALKEVVASAESMLRVA---RARIATLERQLKDTKAEF 180
             S       L +EL K+R ++ E L+++    ES    A   R ++  L    +  K E 
Sbjct: 820  VSK------LEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEM 873

Query: 181  EIAKKKHKDLEQLVNRLAIERSHATVKVKELR---EQAETAEQVAQSRVSEQKARTEFLQ 237
            +  K++   +E+ +  L  +  +  + + +L    +Q +T  +   + V E +      +
Sbjct: 874  DQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE 933

Query: 238  AKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEP 297
             ++ E  + + V                 QLQ  RD  ++   +      +Y   K+   
Sbjct: 934  TELTEALQKREVLETELQNAHGELKSTLRQLQELRD-VLQKAQLSLEE--KYTTIKDLTA 990

Query: 298  TDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELL 357
              RE ++  E++  +  LL  ++ L++   E         R AQ    +    +   E+ 
Sbjct: 991  ELRECKM--EIEDKKQELLEMDQALKERNWELKQ------RAAQVTHLDMTIREHRGEM- 1041

Query: 358  DREQKIVKLQQTID----EQRENEKSMEQTMTQYENQLAALR 395
              EQKI+KL+ T++    E +E  K +E    + +N    LR
Sbjct: 1042 --EQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLR 1081



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 59/293 (20%), Positives = 130/293 (44%), Gaps = 34/293 (11%)

Query: 131 YQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDL 190
           +Q++ EEL  E+A+  +        ES +    +++ TLE+QL++    +     K+ +L
Sbjct: 552 FQLIQEELL-EKASNSS------KLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAEL 604

Query: 191 EQ-LVNRLAIERSHAT---VKVKELREQAETAEQVAQSRVSEQKARTEFLQAKV------ 240
           EQ L+ +    RS  T    + +++    E A+++   +  E + + E L+A++      
Sbjct: 605 EQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQ 664

Query: 241 -AEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD 299
             EQEK+ ++                  L   +   ++  +M++   L+ +  + +E T 
Sbjct: 665 FKEQEKTMSMLQQDIICKQHHLESLDRLLTESKG-EMKKENMKKDEALKALQNQVSEETI 723

Query: 300 RETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATE---L 356
           +  ++   L++ +  L+     L Q    K+ F   L +  + E     Q ++  +   L
Sbjct: 724 KVRQLDSALEICKEELVL---HLNQLEGNKEKFEKQLKK--KSEEVYCLQKELKIKNHSL 778

Query: 357 LDREQKIVKLQQTIDEQRE-------NEKSMEQTMTQYENQLAALRLEVKRLR 402
            +  ++ V LQ T+ +Q++           +E T T+ E Q++ L  E+++ R
Sbjct: 779 QETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQR 831


>AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.
          Length = 2871

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 76/411 (18%), Positives = 157/411 (38%), Gaps = 28/411 (6%)

Query: 41   NLEWKTRNTE--FDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQ 98
            NL W+   +E         + R+   + E    K  +  E+AK+     + M     + +
Sbjct: 1152 NLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYE 1211

Query: 99   KENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESM 158
             E +I +  + E S ++ ++         S N +   + LS+E   R+   E+V   +S+
Sbjct: 1212 TEINITKTTIKEISMQKEDD---------SKNLRNQLDRLSREN--RDLKDEIVRLNDSI 1260

Query: 159  LRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETA 218
            L+    R    E  L+      EI +KK + LE  + ++  +RS    + K+  E+A   
Sbjct: 1261 LQATEQRRRAEENALQQKACGSEIMQKK-QHLEIELKQVMQQRSEDNARHKQSLEEAAKT 1319

Query: 219  EQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRL 278
             Q     +   KA  +    +  E E   +                     +    +I  
Sbjct: 1320 IQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQ 1379

Query: 279  VDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSR 338
            + M++         + +  T     + +E++  +  L ++ E LR+   +      + S 
Sbjct: 1380 LTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSE 1439

Query: 339  IAQGEGTESFQDKMATELLDRE-----QKIVKLQQTIDEQRENEKSMEQTMTQYENQLAA 393
            ++Q +     + +  T++   E     Q +    +TI ++ +  + ++Q + +  N    
Sbjct: 1440 VSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC 1499

Query: 394  LRLEVKRLR--NYDCYSKDVSYPEL-------QTEILDLHLQVETLSRERT 435
            L  E  RL+   YD    + S  E        + E+  L +  E +S+ERT
Sbjct: 1500 LEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERT 1550



 Score = 40.3 bits (90), Expect = 0.015
 Identities = 62/357 (17%), Positives = 142/357 (39%), Gaps = 20/357 (5%)

Query: 55   TERLHRMVAGIAENLKAKINFSLEIAKIPWL-DRDTMIKKIERLQKENSILQ---HKVDE 110
            TE   R    + +  K   + + EI ++  L D++T  +K   L+ EN+ LQ   + + +
Sbjct: 1459 TEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKC--LEDENARLQRVQYDLQK 1516

Query: 111  TSKKENEEPPCHPVQSGSYN-YQVLNEELSKERAAREALKEVVASAESMLRVARARIATL 169
             +    E      VQ       ++  E +S+ER  ++       ++   L++ + ++   
Sbjct: 1517 ANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEE 1576

Query: 170  ERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQ 229
              +LK T +E    +KK   LE+ +  +        +K+  L +Q E A  V +    + 
Sbjct: 1577 LNRLKRTASEDSCKRKK---LEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDL 1633

Query: 230  KARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEY 289
            + + + L   + E+++++                   + +S +   +R    ++      
Sbjct: 1634 RQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKA----- 1688

Query: 290  VPCKENEPTDRETEIWKELQMTRGAL---LRSEEELRQSRAEKDSFLNSLSRIAQGEGTE 346
            +  K     + + EI +   +T       L  EEELR  R E D      S     +   
Sbjct: 1689 IEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNAT 1748

Query: 347  SFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRN 403
              +  + ++L     + ++LQ  I++ +   +++ Q + +++ Q       ++  +N
Sbjct: 1749 ILE--LRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKN 1803



 Score = 37.1 bits (82), Expect = 0.14
 Identities = 65/396 (16%), Positives = 172/396 (43%), Gaps = 23/396 (5%)

Query: 56   ERLHRMVAGIAENLKAKINFSLEIAKIPW-LDRDTMIKKIER--LQKENSILQHKVDETS 112
            ++L   + G+  +LK +   +++I  +   L++ +++KK     L+++  +L   + E  
Sbjct: 1592 KKLEEELEGMRRSLKEQ---AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQ 1648

Query: 113  KKENEEPPCHPVQSGSYNYQVLNEELSKERA--AREALKEVVASAESMLRVARARIATLE 170
            + + EE      +  +   Q+L E+ S ++A    E  ++ +      L  ++  I  L+
Sbjct: 1649 RTQ-EELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQ 1707

Query: 171  RQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA----TVKVKELREQAETAEQVA---Q 223
               ++   E  + +++ ++L    + L   RS A       + ELR Q + +       Q
Sbjct: 1708 SLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQ 1767

Query: 224  SRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER 283
              +++ +   E L+ ++ + +K    A                + +S   + I++++ ++
Sbjct: 1768 GLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVK-IKVLEQDK 1826

Query: 284  RRC--LEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQ 341
             R   LE    +     + ET + + L+  +  +     + +   + K+  +  +   ++
Sbjct: 1827 ARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIE--SE 1884

Query: 342  GEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRL 401
             E +E  ++ + +E+   + +I ++++    +R+ E S  +T +Q E + +  + E+ +L
Sbjct: 1885 REKSEREKNSLRSEIERLQAEIKRIEERC--RRKLEDSTRETQSQLETERSRYQREIDKL 1942

Query: 402  RNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            R     S   +  E +  +    L  + L ++ TA+
Sbjct: 1943 RQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAM 1978


>AK131080-1|BAC85130.1|  563|Homo sapiens FLJ00279 protein protein.
          Length = 563

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 61/234 (26%), Positives = 105/234 (44%), Gaps = 35/234 (14%)

Query: 45  KTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLD--RDTMIKKIERLQKENS 102
           + R  E + + ER  R +A +A   K +++     A I   +  RD  IK++ +LQ +  
Sbjct: 193 QVREMEAELEDERKQRSMA-VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 251

Query: 103 ILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEEL-SKERAAREALKEVVASAE 156
               ++D+T     E     +     ++S       L EEL + ERA R+A +E    A+
Sbjct: 252 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 311

Query: 157 SML-------------RVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRLAI 199
            +              R   ARIA LE +L++ +   E+     KK +  ++Q+   L +
Sbjct: 312 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 371

Query: 200 ERSHATVKVKELREQAETAEQVAQSRVSEQ--------KARTEFLQAKVAEQEK 245
           ERSHA  K +  R+Q E   +  + ++ E         KA    L+AK+A+ E+
Sbjct: 372 ERSHAQ-KNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 424



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 50/313 (15%), Positives = 122/313 (38%), Gaps = 10/313 (3%)

Query: 87  RDTMIKKIERLQKENSILQHKVDETSKKENE-EPPCHPVQSGSY----NYQVLNEELSKE 141
           +D + K +  L+K    L+ +V+E   +  E E      +        N Q +  +  ++
Sbjct: 116 KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERD 175

Query: 142 RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIER 201
              R+   E     + ++R  R   A LE + K         KK   DL+ L   +    
Sbjct: 176 LQGRDEQSE--EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 233

Query: 202 SHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
            +    +K+LR+     +   +     + +R E L      ++K K++            
Sbjct: 234 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 293

Query: 262 XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD-RETEIWKELQMTRGALLRSEE 320
                + Q+ ++R     ++        +  +E    + R  ++ +EL+  +G      +
Sbjct: 294 AAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 353

Query: 321 ELRQSRAEKDSFLNSLS-RIAQGEGTESFQDKMATELLDREQKIVKLQQTI-DEQRENEK 378
            L+++  + D     L+   +  +  E+ + ++  +  + + K+ +++ T+  + + +  
Sbjct: 354 RLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASIT 413

Query: 379 SMEQTMTQYENQL 391
           ++E  + Q E QL
Sbjct: 414 ALEAKIAQLEEQL 426



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 39/183 (21%), Positives = 75/183 (40%), Gaps = 11/183 (6%)

Query: 42  LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKEN 101
           LE +  NTE  ND  RL +    I +     IN  L + +      +   +++ER  KE 
Sbjct: 341 LEEEQGNTELIND--RLKKANLQIDQ-----INTDLNLERSHAQKNENARQQLERQNKEL 393

Query: 102 SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRV 161
            +   +++ T K + +      + +       L E+L  E   R+A  + V   E  L+ 
Sbjct: 394 KVKLQEMEGTVKSKYKAS----ITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 449

Query: 162 ARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQV 221
              ++    R  +  K + + A  + K L++ +     E   A    ++L+ + E A + 
Sbjct: 450 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATET 509

Query: 222 AQS 224
           A +
Sbjct: 510 ADA 512


>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
            (5'partial) protein.
          Length = 1857

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 68/320 (21%), Positives = 136/320 (42%), Gaps = 18/320 (5%)

Query: 88   DTMIKKIERLQK-ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            D + K  ER QK EN + + +   +   E +      +Q+ +  Y    E   +  A ++
Sbjct: 744  DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 803

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
             L+E++   E+ L     R   L+ + K    +    +++ ++ E    +L +E+  A  
Sbjct: 804  ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 863

Query: 207  KVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            K+K+L ++    +        E+K    R   L   +AE+E+                  
Sbjct: 864  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 923

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
               +L+   ++S + ++  +R+          +  D + +I  EL+M    L + EEEL+
Sbjct: 924  LEVRLKK-EEKSRQELEKLKRKLEGDASDFHEQIADLQAQI-AELKM---QLAKKEEELQ 978

Query: 324  QSRAEKDSFL----NSLSRIAQGEG-TESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
             + A  D  +    N+L +I + EG     Q+ + +E   R  K  K ++ + E+ E  K
Sbjct: 979  AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR-NKAEKQKRDLGEELEALK 1037

Query: 379  S-MEQTM--TQYENQLAALR 395
            + +E T+  T  + +L A R
Sbjct: 1038 TELEDTLDSTATQQELRAKR 1057



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 61/236 (25%), Positives = 108/236 (45%), Gaps = 33/236 (13%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI-AKIPWLDRDTMIKKIERLQKE 100
            L+ +    E + + ER  R +A  A+         LE+ A      R+  IK++ +LQ +
Sbjct: 1479 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 1538

Query: 101  NSILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEELSK-ERAAREA------L 148
                Q ++++     +E     +      +S   +   L E+L+  ERA ++A      L
Sbjct: 1539 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1598

Query: 149  KEVVASA-------ESMLRVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRL 197
             E +AS+       +   R   ARIA LE +L++ +   E      +K  +  EQL N L
Sbjct: 1599 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1658

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQK--ARTEF------LQAKVAEQEK 245
            A ERS A  K +  R+Q E   +  +S++ E +   +++F      L+AK+A+ E+
Sbjct: 1659 ATERSTAQ-KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1713



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 47/281 (16%), Positives = 120/281 (42%), Gaps = 14/281 (4%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EE+  +    +  KE    AE+ L+    + + L  +    + + +   + + + E++  
Sbjct: 737  EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 796

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTE---FLQAKVAEQEKSKAVAXX 252
            RLA ++      + E+  + E  E   Q   +E+K   +    L+ ++ E+E ++     
Sbjct: 797  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 856

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM-T 311
                          ++    D++ +L   ER+   E +        + E +     ++  
Sbjct: 857  EKVTAEAKIKKLEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 915

Query: 312  RGALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            +   + SE E+R  + EK    L  L R  +G+ ++ F +++A    D + +I +L+  +
Sbjct: 916  KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIA----DLQAQIAELKMQL 970

Query: 371  DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
                + E+ ++  + + ++++A     +K++R  + +  D+
Sbjct: 971  ---AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1008



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 79/398 (19%), Positives = 155/398 (38%), Gaps = 36/398 (9%)

Query: 19   LRDMESRAGVAAETLGE-VRVLSNLEW--KTRNTEFDNDTERLHRMVAGIAENLKAKINF 75
            LR +E       + L E +    NLE    T N +  +  ++L    + +    + K  F
Sbjct: 1223 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1282

Query: 76   SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEPPCHPVQSGSYNY-QV 133
              EI  +     +      ++L+K  + LQ ++D+     +N+      ++     + Q+
Sbjct: 1283 QKEIENLTQ-QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1341

Query: 134  LNEELS--------KERAAREALKEVVASAESMLRVARARIAT---LERQLKDTKAEFEI 182
            L EE +        ++RA  EA +E    A S+ R     +     LER  K  KAE E 
Sbjct: 1342 LAEEKNISSKYADERDRAEAEA-REKETKALSLARALEEALEAKEELERTNKMLKAEMED 1400

Query: 183  AKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVA 241
                  D+ + V+ L   +     +++E++ Q E  E   Q+   + K R E  +QA   
Sbjct: 1401 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQA-TEDAKLRLEVNMQALKG 1459

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDR 300
            + E+                     QLQ    +    L D  ++R L     K+ E    
Sbjct: 1460 QFERD-------LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD-- 1510

Query: 301  ETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE 360
                 K+L++   + ++  EE  +   +  + +    R  + E   + +D++     + E
Sbjct: 1511 ----LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR--ELEDARASRDEIFATAKENE 1564

Query: 361  QKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +K   L+  + + +E+  + E+   Q + +   L  E+
Sbjct: 1565 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1602



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 39/185 (21%), Positives = 77/185 (41%), Gaps = 16/185 (8%)

Query: 307 ELQMTRGALLRSEEELR---QSRAEKDSFLNSLSRIAQGEG-----TESFQDKMATELLD 358
           ELQ T+    ++E EL+   Q  ++     N L    Q E       E  + ++A +  +
Sbjct: 745 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 804

Query: 359 REQKIVKLQQTIDEQREN-------EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
            E+ + +++  ++E+ +         K M Q M   E QL       ++L+  +  + + 
Sbjct: 805 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEA 863

Query: 412 SYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAAL 471
              +L+ EIL +  Q   LS+ER  L    +     L   E  A    ++    + + + 
Sbjct: 864 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 923

Query: 472 LDGRI 476
           L+ R+
Sbjct: 924 LEVRL 928



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 75/385 (19%), Positives = 155/385 (40%), Gaps = 23/385 (5%)

Query: 35   EVRVLSN-LEWKTRNTEFDNDTERLHRMVAGIAENLKAKIN-FSLEIAKIPWLDRDTMIK 92
            EV VL   L+ +TR+ E     + + +  A   E L  ++  F    A +   ++ T+ K
Sbjct: 1060 EVTVLKKALDEETRSHEAQ--VQEMRQKHAQAVEELTEQLEQFKRAKANLD-KNKQTLEK 1116

Query: 93   KIERLQKENSIL-QHKVDETSKKENEEPPCHPVQS----GSYNYQVLNEELSKERAAREA 147
            +   L  E  +L Q K +   KK+  E     +QS    G      LN+++ K +   E+
Sbjct: 1117 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVES 1176

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +  ++  AE         +A+L  QL+DT+   +   ++  ++   + +L  ER+    +
Sbjct: 1177 VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQ 1236

Query: 208  VKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSK---AVAXXXXXXXXXXX 261
            + E  E  +  E+       ++S+ K + +   + V   E+ K                 
Sbjct: 1237 LDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEK 1296

Query: 262  XXXXXQLQSFRDRSIR-----LVDMERRRCLEYVPCKENEPTDRETEIWKELQMT-RGAL 315
                 +L+  ++R  +     +VD++ +R L     K+    D+     K +        
Sbjct: 1297 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1356

Query: 316  LRSEEELRQSRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
             R+E E R+   +  S   +L    +  E  E     +  E+ D       + + + E  
Sbjct: 1357 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1416

Query: 375  ENEKSMEQTMTQYENQLAALRLEVK 399
            ++++++E  M + + QL  L  E++
Sbjct: 1417 KSKRALETQMEEMKTQLEELEDELQ 1441



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 17/130 (13%)

Query: 135  NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA----KKKHKDL 190
            N+EL  +    E    V +  +S +    A+IA LE Q++    E + A    K+K K L
Sbjct: 1679 NKELRSKLHEMEGA--VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1736

Query: 191  EQLVNRLAIERSHA----------TVKVKELREQAETAEQVAQS-RVSEQKARTEFLQAK 239
            ++++ ++  ER  A            +VK+L+ Q E AE+ +Q    + +K + E  +A 
Sbjct: 1737 KEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEAT 1796

Query: 240  VAEQEKSKAV 249
             + +   + V
Sbjct: 1797 ESNEAMGREV 1806


>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
          Length = 1984

 Score = 43.2 bits (97), Expect = 0.002
 Identities = 68/320 (21%), Positives = 136/320 (42%), Gaps = 18/320 (5%)

Query: 88   DTMIKKIERLQK-ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
            D + K  ER QK EN + + +   +   E +      +Q+ +  Y    E   +  A ++
Sbjct: 871  DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 930

Query: 147  ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
             L+E++   E+ L     R   L+ + K    +    +++ ++ E    +L +E+  A  
Sbjct: 931  ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 990

Query: 207  KVKELREQAETAEQVAQSRVSEQK---ARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
            K+K+L ++    +        E+K    R   L   +AE+E+                  
Sbjct: 991  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1050

Query: 264  XXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELR 323
               +L+   ++S + ++  +R+          +  D + +I  EL+M    L + EEEL+
Sbjct: 1051 LEVRLKK-EEKSRQELEKLKRKLEGDASDFHEQIADLQAQI-AELKM---QLAKKEEELQ 1105

Query: 324  QSRAEKDSFL----NSLSRIAQGEG-TESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
             + A  D  +    N+L +I + EG     Q+ + +E   R  K  K ++ + E+ E  K
Sbjct: 1106 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR-NKAEKQKRDLGEELEALK 1164

Query: 379  S-MEQTM--TQYENQLAALR 395
            + +E T+  T  + +L A R
Sbjct: 1165 TELEDTLDSTATQQELRAKR 1184



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 61/236 (25%), Positives = 108/236 (45%), Gaps = 33/236 (13%)

Query: 42   LEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEI-AKIPWLDRDTMIKKIERLQKE 100
            L+ +    E + + ER  R +A  A+         LE+ A      R+  IK++ +LQ +
Sbjct: 1606 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 1665

Query: 101  NSILQHKVDETSKKENE-----EPPCHPVQSGSYNYQVLNEELSK-ERAAREA------L 148
                Q ++++     +E     +      +S   +   L E+L+  ERA ++A      L
Sbjct: 1666 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1725

Query: 149  KEVVASA-------ESMLRVARARIATLERQLKDTKAEFEI----AKKKHKDLEQLVNRL 197
             E +AS+       +   R   ARIA LE +L++ +   E      +K  +  EQL N L
Sbjct: 1726 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1785

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQK--ARTEF------LQAKVAEQEK 245
            A ERS A  K +  R+Q E   +  +S++ E +   +++F      L+AK+A+ E+
Sbjct: 1786 ATERSTAQ-KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1840



 Score = 37.5 bits (83), Expect = 0.11
 Identities = 47/281 (16%), Positives = 120/281 (42%), Gaps = 14/281 (4%)

Query: 136  EELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EE+  +    +  KE    AE+ L+    + + L  +    + + +   + + + E++  
Sbjct: 864  EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 923

Query: 196  RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTE---FLQAKVAEQEKSKAVAXX 252
            RLA ++      + E+  + E  E   Q   +E+K   +    L+ ++ E+E ++     
Sbjct: 924  RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL 983

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM-T 311
                          ++    D++ +L   ER+   E +        + E +     ++  
Sbjct: 984  EKVTAEAKIKKLEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1042

Query: 312  RGALLRSEEELRQSRAEKD-SFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
            +   + SE E+R  + EK    L  L R  +G+ ++ F +++A    D + +I +L+  +
Sbjct: 1043 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIA----DLQAQIAELKMQL 1097

Query: 371  DEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
                + E+ ++  + + ++++A     +K++R  + +  D+
Sbjct: 1098 ---AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1135



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 79/398 (19%), Positives = 155/398 (38%), Gaps = 36/398 (9%)

Query: 19   LRDMESRAGVAAETLGE-VRVLSNLEW--KTRNTEFDNDTERLHRMVAGIAENLKAKINF 75
            LR +E       + L E +    NLE    T N +  +  ++L    + +    + K  F
Sbjct: 1350 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1409

Query: 76   SLEIAKIPWLDRDTMIKKIERLQKENSILQHKVDE-TSKKENEEPPCHPVQSGSYNY-QV 133
              EI  +     +      ++L+K  + LQ ++D+     +N+      ++     + Q+
Sbjct: 1410 QKEIENLTQ-QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1468

Query: 134  LNEELS--------KERAAREALKEVVASAESMLRVARARIAT---LERQLKDTKAEFEI 182
            L EE +        ++RA  EA +E    A S+ R     +     LER  K  KAE E 
Sbjct: 1469 LAEEKNISSKYADERDRAEAEA-REKETKALSLARALEEALEAKEELERTNKMLKAEMED 1527

Query: 183  AKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF-LQAKVA 241
                  D+ + V+ L   +     +++E++ Q E  E   Q+   + K R E  +QA   
Sbjct: 1528 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQA-TEDAKLRLEVNMQALKG 1586

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQ-SFRDRSIRLVDMERRRCLEYVPCKENEPTDR 300
            + E+                     QLQ    +    L D  ++R L     K+ E    
Sbjct: 1587 QFERD-------LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD-- 1637

Query: 301  ETEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE 360
                 K+L++   + ++  EE  +   +  + +    R  + E   + +D++     + E
Sbjct: 1638 ----LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQR--ELEDARASRDEIFATAKENE 1691

Query: 361  QKIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEV 398
            +K   L+  + + +E+  + E+   Q + +   L  E+
Sbjct: 1692 KKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL 1729



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 39/185 (21%), Positives = 77/185 (41%), Gaps = 16/185 (8%)

Query: 307  ELQMTRGALLRSEEELR---QSRAEKDSFLNSLSRIAQGEG-----TESFQDKMATELLD 358
            ELQ T+    ++E EL+   Q  ++     N L    Q E       E  + ++A +  +
Sbjct: 872  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 931

Query: 359  REQKIVKLQQTIDEQREN-------EKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDV 411
             E+ + +++  ++E+ +         K M Q M   E QL       ++L+  +  + + 
Sbjct: 932  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ-LEKVTAEA 990

Query: 412  SYPELQTEILDLHLQVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAAL 471
               +L+ EIL +  Q   LS+ER  L    +     L   E  A    ++    + + + 
Sbjct: 991  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1050

Query: 472  LDGRI 476
            L+ R+
Sbjct: 1051 LEVRL 1055



 Score = 32.7 bits (71), Expect = 3.0
 Identities = 75/385 (19%), Positives = 155/385 (40%), Gaps = 23/385 (5%)

Query: 35   EVRVLSN-LEWKTRNTEFDNDTERLHRMVAGIAENLKAKIN-FSLEIAKIPWLDRDTMIK 92
            EV VL   L+ +TR+ E     + + +  A   E L  ++  F    A +   ++ T+ K
Sbjct: 1187 EVTVLKKALDEETRSHEAQ--VQEMRQKHAQAVEELTEQLEQFKRAKANLD-KNKQTLEK 1243

Query: 93   KIERLQKENSIL-QHKVDETSKKENEEPPCHPVQS----GSYNYQVLNEELSKERAAREA 147
            +   L  E  +L Q K +   KK+  E     +QS    G      LN+++ K +   E+
Sbjct: 1244 ENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVES 1303

Query: 148  LKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVK 207
            +  ++  AE         +A+L  QL+DT+   +   ++  ++   + +L  ER+    +
Sbjct: 1304 VTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQ 1363

Query: 208  VKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKSK---AVAXXXXXXXXXXX 261
            + E  E  +  E+       ++S+ K + +   + V   E+ K                 
Sbjct: 1364 LDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEK 1423

Query: 262  XXXXXQLQSFRDRSIR-----LVDMERRRCLEYVPCKENEPTDRETEIWKELQMT-RGAL 315
                 +L+  ++R  +     +VD++ +R L     K+    D+     K +        
Sbjct: 1424 AAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADER 1483

Query: 316  LRSEEELRQSRAEKDSFLNSLSRIAQG-EGTESFQDKMATELLDREQKIVKLQQTIDEQR 374
             R+E E R+   +  S   +L    +  E  E     +  E+ D       + + + E  
Sbjct: 1484 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1543

Query: 375  ENEKSMEQTMTQYENQLAALRLEVK 399
            ++++++E  M + + QL  L  E++
Sbjct: 1544 KSKRALETQMEEMKTQLEELEDELQ 1568



 Score = 32.3 bits (70), Expect = 4.0
 Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 17/130 (13%)

Query: 135  NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA----KKKHKDL 190
            N+EL  +    E    V +  +S +    A+IA LE Q++    E + A    K+K K L
Sbjct: 1806 NKELRSKLHEMEGA--VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1863

Query: 191  EQLVNRLAIERSHA----------TVKVKELREQAETAEQVAQS-RVSEQKARTEFLQAK 239
            ++++ ++  ER  A            +VK+L+ Q E AE+ +Q    + +K + E  +A 
Sbjct: 1864 KEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEAT 1923

Query: 240  VAEQEKSKAV 249
             + +   + V
Sbjct: 1924 ESNEAMGREV 1933


>BC098576-1|AAH98576.1|  918|Homo sapiens inner centromere protein
           antigens 135/155kDa protein.
          Length = 918

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 62/253 (24%), Positives = 103/253 (40%), Gaps = 15/253 (5%)

Query: 141 ERAAREALKEVVASAESMLRV---ARARIATL-ERQLKDTKAEF-EIAKKKHKDLEQLVN 195
           E   R  L+EV    E  LR    AR R+  + E + K  + +F +I +K  K  E+ + 
Sbjct: 560 EEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA 619

Query: 196 RLAIERSHATVKVKEL---REQAETAEQVAQSRVSEQKAR-TEFLQAKVAE-QEKSKAVA 250
               ++  A  K++E+   R+Q E A ++   +  E++ R  E LQ K  E QE+ +  A
Sbjct: 620 EEKAKKKAAAKKMEEVEARRKQEEDARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA 679

Query: 251 XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM 310
                           + +    R     + ERR     +  +E        +  +ELQ 
Sbjct: 680 EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQE 739

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
              AL   +E+L++   EK        R+A+ +  E  Q+K A E     +    L  T+
Sbjct: 740 REKALRLQKEQLQRELEEKKK-KEEQQRLAERQLQEE-QEKKAKEAAGASK---ALNVTV 794

Query: 371 DEQRENEKSMEQT 383
           D Q     S + T
Sbjct: 795 DVQSPACTSYQMT 807



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 39/163 (23%), Positives = 83/163 (50%), Gaps = 8/163 (4%)

Query: 88  DTMIKKIERLQKENSILQH--KVDETSKKENEEPPCH-PVQSGSYNYQVLNEELSKERAA 144
           +  +K+ ERL+K     +   ++ E  KK+ E+       ++     + L EE +K++AA
Sbjct: 569 EVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAA 628

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            + ++EV A  +      R R   L+++ ++ + +  + KKK ++ E+L  + A  +  A
Sbjct: 629 AKKMEEVEARRKQEEDARRLR--WLQQEEEERRHQELLQKKKEEEQERL-RKAAEAKRLA 685

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
             + +E REQ    ++  +    EQ+ R +  + ++AEQE+ +
Sbjct: 686 EQREQERREQERREQERREQERREQERREQ--ERQLAEQERRR 726


>BC046212-1|AAH46212.1|  364|Homo sapiens Similar to cytomatrix
           protein p110 protein.
          Length = 364

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 63/326 (19%), Positives = 135/326 (41%), Gaps = 24/326 (7%)

Query: 94  IERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVA 153
           +E  +++ ++LQ K++   ++  ++     + +     + L  + S    A   L+E ++
Sbjct: 5   LEVKERKINVLQKKIENLQEQLRDKDK--QLTNLKDRVKSLQTDSSNTDTALATLEEALS 62

Query: 154 SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELRE 213
             E ++   + +    ER  ++   E E  +K++KDL++ VN L  E +     + +L+E
Sbjct: 63  EKERIIERLKEQ---RERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKE 119

Query: 214 QAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRD 273
            A +       R S+ K+    ++ K  E  K +A                   ++    
Sbjct: 120 HASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNIEDDSR 179

Query: 274 RSIRLVD----MERRRCLEYVPC-KENEPTDRETEIWKELQMTRGALLRSEEELRQSRAE 328
            +    D    +++        C K     DR  EI KE++  +    +   EL +   +
Sbjct: 180 MNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKD 239

Query: 329 KDSFLNSLSRIAQGEGTESFQ---------DKMA--TELLDREQ---KIVKLQQTIDEQR 374
           ++  + +L    Q E  ++ Q         D MA  ++ L  E+    + K +Q +D  +
Sbjct: 240 QNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATK 299

Query: 375 ENEKSMEQTMTQYENQLAALRLEVKR 400
               S +Q++ + E  LA LR+E ++
Sbjct: 300 ARLASTQQSLAEKEAHLANLRIERRK 325



 Score = 35.1 bits (77), Expect = 0.56
 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 9/118 (7%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVAR-ARIATLERQLKDTKAEFEIAKKKHKDLEQL 193
           N++L K++ A + L+EV    +SM   ++  +I  L   L+ T+ E +  K +    +Q 
Sbjct: 250 NQQLEKKKNA-QLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQ- 307

Query: 194 VNRLAIERSH-ATVKV---KELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
              LA + +H A +++   K+L E  E  ++   + +SE+ A    L+   ++++K K
Sbjct: 308 --SLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKKK 363



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 45/191 (23%), Positives = 78/191 (40%), Gaps = 13/191 (6%)

Query: 63  AGIAENLKAK-INFSLEIAKIPWLDRDTMIKK-IERLQKENSILQHKVDETSKKENEEPP 120
           AG+  + K K +  ++E  K      +  +KK  E+L  +     H +++ S+   E   
Sbjct: 127 AGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEF-- 184

Query: 121 CHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKD----- 175
              ++          +E  K +A  + L E++   E+       +IA LER +KD     
Sbjct: 185 ADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKV 244

Query: 176 --TKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKART 233
              K   ++ KKK+  L + V R   E S A        E+   A +  +  +   KAR 
Sbjct: 245 ANLKHNQQLEKKKNAQLLEEVRRR--EDSMADNSQHLQIEELMNALEKTRQELDATKARL 302

Query: 234 EFLQAKVAEQE 244
              Q  +AE+E
Sbjct: 303 ASTQQSLAEKE 313


>BC017837-1|AAH17837.1|  311|Homo sapiens Unknown (protein for
           IMAGE:4270936) protein.
          Length = 311

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 33/97 (34%), Positives = 54/97 (55%), Gaps = 5/97 (5%)

Query: 135 NEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAE-FEIAKKKHKDL-EQ 192
           +EEL KE    + L++  A  + ++  + A + +LE+QL++ + E F I  K+ KDL EQ
Sbjct: 106 SEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNI--KQMKDLFEQ 163

Query: 193 LVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQ 229
              +LA E +    K  E R   E AEQ   +R++E+
Sbjct: 164 KAAQLATEIADIKSKYDEERSLREAAEQKV-TRLTEE 199



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 24/103 (23%), Positives = 48/103 (46%), Gaps = 4/103 (3%)

Query: 134 LNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA--KKKHKDLE 191
           +  +  +ER+ REA ++ V      L      I  L+ +L       ++A  KK+   ++
Sbjct: 175 IKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQ 234

Query: 192 QLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTE 234
            L++ + +ER   + K+K+  E  +   Q A S  +  + R+E
Sbjct: 235 TLMDNMTLERERESEKLKD--ECKKLQSQYASSEATISQLRSE 275


>AY714053-1|AAU04398.1|  918|Homo sapiens inner centromere protein
           protein.
          Length = 918

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 62/253 (24%), Positives = 103/253 (40%), Gaps = 15/253 (5%)

Query: 141 ERAAREALKEVVASAESMLRV---ARARIATL-ERQLKDTKAEF-EIAKKKHKDLEQLVN 195
           E   R  L+EV    E  LR    AR R+  + E + K  + +F +I +K  K  E+ + 
Sbjct: 560 EEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA 619

Query: 196 RLAIERSHATVKVKEL---REQAETAEQVAQSRVSEQKAR-TEFLQAKVAE-QEKSKAVA 250
               ++  A  K++E+   R+Q E A ++   +  E++ R  E LQ K  E QE+ +  A
Sbjct: 620 EEKAKKKAAAKKMEEVEARRKQEEDARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA 679

Query: 251 XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM 310
                           + +    R     + ERR     +  +E        +  +ELQ 
Sbjct: 680 EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQE 739

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
              AL   +E+L++   EK        R+A+ +  E  Q+K A E     +    L  T+
Sbjct: 740 REKALRLQKEQLQRELEEKKK-KEEQQRLAERQLQEE-QEKKAKEAAGASK---ALNVTV 794

Query: 371 DEQRENEKSMEQT 383
           D Q     S + T
Sbjct: 795 DVQSPACTSYQMT 807



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 39/163 (23%), Positives = 83/163 (50%), Gaps = 8/163 (4%)

Query: 88  DTMIKKIERLQKENSILQH--KVDETSKKENEEPPCH-PVQSGSYNYQVLNEELSKERAA 144
           +  +K+ ERL+K     +   ++ E  KK+ E+       ++     + L EE +K++AA
Sbjct: 569 EVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAA 628

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            + ++EV A  +      R R   L+++ ++ + +  + KKK ++ E+L  + A  +  A
Sbjct: 629 AKKMEEVEARRKQEEDARRLR--WLQQEEEERRHQELLQKKKEEEQERL-RKAAEAKRLA 685

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
             + +E REQ    ++  +    EQ+ R +  + ++AEQE+ +
Sbjct: 686 EQREQERREQERREQERREQERREQERREQ--ERQLAEQERRR 726


>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
            kinase protein.
          Length = 2027

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 46/208 (22%), Positives = 87/208 (41%), Gaps = 25/208 (12%)

Query: 40   SNLEWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQK 99
            S  E + R  +   DTE+  R  A        +I  S ++ ++   +    I  +++  K
Sbjct: 1055 SQFECRVRELQRMLDTEKQSRARAD------QRITESRQVVELAVKEHKAEILALQQALK 1108

Query: 100  ENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESML 159
            E  +   K +  S K N+    H +     N + L ++L  ER  ++ L E  A  +  +
Sbjct: 1109 EQKL---KAESLSDKLNDLEKKHAMLE--MNARSLQQKLETERELKQRLLEEQAKLQQQM 1163

Query: 160  RVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAE 219
             + +  I  L + L++     ++ K +  DLE  +  + +  SH  VK+           
Sbjct: 1164 DLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKM----------- 1212

Query: 220  QVAQSRVSEQKARTEFLQAKVAEQEKSK 247
               +  +S+Q    +FLQAK+ +  K K
Sbjct: 1213 ---EGTISQQTKLIDFLQAKMDQPAKKK 1237



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 70/405 (17%), Positives = 168/405 (41%), Gaps = 24/405 (5%)

Query: 88  DTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREA 147
           ++++  ++   K +S+ +  + ++ + ++ +  CH ++           E+    + +E 
Sbjct: 432 ESVVSGLDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEV 491

Query: 148 LKEVVASAESMLRVARARIATLERQLKDT--KAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
             +   +  S+L    A   T    LK +  +A  E++++  K L QL++ +  E+S   
Sbjct: 492 ELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKAL-QLLHDIR-EQSRKL 549

Query: 206 VKVKELREQAETAE------QVAQSRVSEQKARTEFLQAKVAEQ----EKSKAVAXXXXX 255
            ++KE   QA+  E      Q+ +  VS ++ R++  ++++ E     E+ K  A     
Sbjct: 550 QEIKEQEYQAQVEEMRLMMNQLEEDLVSARR-RSDLYESELRESRLAAEEFKRKATECQH 608

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGAL 315
                      ++  +    +  ++ E++  ++ +  K  +     TE  + LQ  R A 
Sbjct: 609 KLLKAKDQGKPEVGEYA--KLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAK 666

Query: 316 LRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRE 375
            R+E EL + +  +DS      ++ +    E  ++K     +  +   V L+Q      E
Sbjct: 667 ERAERELEKLQNREDSSEGIRKKLVE---AEELEEKHREAQVSAQHLEVHLKQKEQHYEE 723

Query: 376 NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERT 435
             K ++  + +       L   ++R    + + K     E +  I  +  ++ +L +   
Sbjct: 724 KIKVLDNQIKKDLADKETLENMMQR-HEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIV 782

Query: 436 ALITA---AASRALMLERHERAADLFARMVRARKDLAALLDGRID 477
            L  A   AA+ +L  +R+ +A +     +R +K       G+++
Sbjct: 783 ELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLE 827



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 65/339 (19%), Positives = 122/339 (35%), Gaps = 21/339 (6%)

Query: 124  VQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA 183
            V+    N    N  L  +R  + A +E+++           +   LE Q  + K E ++ 
Sbjct: 782  VELSEANKLAANSSLFTQRNMK-AQEEMISELRQQKFYLETQAGKLEAQ--NRKLEEQLE 838

Query: 184  KKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEF--LQAKVA 241
            K  H+D       L +E     V ++   ++ E   Q+ + ++S Q+  ++   LQA  A
Sbjct: 839  KISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARA 898

Query: 242  EQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRE 301
              E     A                 L + RD   R  D  R  C      +E    ++ 
Sbjct: 899  ALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQ--LNQL 956

Query: 302  TEIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ 361
            TE   EL      L    ++L ++    D  +   S +          D +  E+ +RE 
Sbjct: 957  TEDNAELNNQNFYL---SKQLDEASGANDEIVQLRSEV----------DHLRREITEREM 1003

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNY-DCYSKDVSYPELQTEI 420
            ++   +QT++  +     +E+ +   E     L  + ++   +      + S  E +   
Sbjct: 1004 QLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRE 1063

Query: 421  LDLHLQVETLSRERTALITAAASRALMLERHERAADLFA 459
            L   L  E  SR R       + + + L   E  A++ A
Sbjct: 1064 LQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILA 1102



 Score = 34.3 bits (75), Expect = 0.98
 Identities = 59/271 (21%), Positives = 116/271 (42%), Gaps = 26/271 (9%)

Query: 152  VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
            + S +  +   +     LE Q+ D +A  +   +K +  E   + L  E+S    +V+EL
Sbjct: 1005 LTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVREL 1064

Query: 212  REQAETAEQ--------VAQSR------VSEQKARTEFLQAKVAEQE-KSKAVA------ 250
            +   +T +Q        + +SR      V E KA    LQ  + EQ+ K+++++      
Sbjct: 1065 QRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDL 1124

Query: 251  XXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQM 310
                            +L++ R+   RL++ E+ +  + +  ++N    R T+  +E  +
Sbjct: 1125 EKKHAMLEMNARSLQQKLETERELKQRLLE-EQAKLQQQMDLQKNH-IFRLTQGLQE-AL 1181

Query: 311  TRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTI 370
             R  LL++E    + + E    L S  ++   EGT S Q K+   L  +  +  K ++ +
Sbjct: 1182 DRADLLKTERSDLEYQLENIQVLYSHEKVKM-EGTISQQTKLIDFLQAKMDQPAKKKKGL 1240

Query: 371  DEQRENEKSM-EQTMTQYENQLAALRLEVKR 400
              +R+ + ++  Q   QY     AL  E  R
Sbjct: 1241 FSRRKEDPALPTQVPLQYNELKLALEKEKAR 1271


>AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein.
          Length = 1943

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 82/391 (20%), Positives = 160/391 (40%), Gaps = 26/391 (6%)

Query: 91   IKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
            +K+ ++L+ +    Q + D   K   EE      Q     ++   +++ ++   R+ L+E
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR-QERDRKFREEEQQVRRQERERKFLEE 1451

Query: 151  VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE 210
                 E  LR  R R    E QL   + E ++ +++ +D + L     + R     K +E
Sbjct: 1452 -----EQQLRQERHRKFREEEQLLQEREEQQLHRQE-RDRKFLEEEQQLRRQERDRKFRE 1505

Query: 211  LREQAETAEQV---AQSRVSEQKARTEFLQAK--VAEQEKSKAVAXXXXXXXXXXXXXXX 265
               +++  E+     + ++  Q+ + +FLQ +  +  QE+ +                  
Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565

Query: 266  X----QL-QSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEE 320
                 QL +  RDR  RL + + RR  +     E+E   R  E  ++L+  R    R +E
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625

Query: 321  ELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELL-DREQKIVKLQQTIDEQRENEKS 379
            +L Q R E+        R    E  +  + +   +L  DR++K  + +Q + E  E +  
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685

Query: 380  MEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEIL-DLHLQVETLSRERTALI 438
             ++   ++  +   LR + +R R +    + +   EL+ +   +  L+ ET   E+  L 
Sbjct: 1686 RQERDRKFREEEQQLRRQ-ERERKFLQEEQQLRRQELERKFREEEQLRQET---EQEQLR 1741

Query: 439  TAAASRALMLE---RHERAADLFARMVRARK 466
                 R ++ E   R ER      R  R RK
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRRQERDRK 1772



 Score = 42.3 bits (95), Expect = 0.004
 Identities = 67/326 (20%), Positives = 132/326 (40%), Gaps = 18/326 (5%)

Query: 84  WLDRDTMIKKIE-RLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKER 142
           W  R+T+++K E +LQ+E    Q ++ E      EE     ++      +   EE  ++R
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQE------EEEQLRKLERQELRRERQEEEQQQQR 299

Query: 143 AAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR-LAIER 201
             RE         E   +    R     R+ ++ + E ++ +++ +  EQ + R    ER
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359

Query: 202 SHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXX 261
               ++ ++  E+ E   +  Q    EQ+ R E  Q +  +Q + +              
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRRE-QQLRREQQLRREQQLRREQQLRREQQ 418

Query: 262 XXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD---RETEIWKELQMTRGALLRS 318
                QL+  ++        E+ R  + +  ++ E  D   RE E  +  Q  R   L+ 
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478

Query: 319 EEELRQSRAEKDSFLNSLSRIAQGEGTESF----QDKMATELLDREQKIVKLQQTIDEQR 374
           ++E  + R E+   L    R  Q E  E      Q++   + L R+++  +LQQ +  ++
Sbjct: 479 DQE--EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536

Query: 375 ENEKSMEQTMTQYENQLAALRLEVKR 400
           +  +  E+   Q   +    RLE +R
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQER 562



 Score = 41.5 bits (93), Expect = 0.006
 Identities = 65/313 (20%), Positives = 125/313 (39%), Gaps = 15/313 (4%)

Query: 85  LDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAA 144
           L R+  +++ ++L++E  + +   ++  ++E EE             Q L  E  + R  
Sbjct: 401 LRREQQLRREQQLRREQQLRR---EQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHA 204
            +  +E     +   +    R    ER+ +  K E E  +++ +  EQ + R   ER   
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517

Query: 205 TVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXX 264
            +K +E  E+ +   +  Q    EQ+ R E L  +  E+EK                   
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR--EEEKRLEQERREQRLKREQEERR 575

Query: 265 XXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQ 324
              L+   +R  + +  E+   LE    K  E    E E  +E ++ R      EEE RQ
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQ-RLKREEVERLEQEERREQRLKRE---EPEEERRQ 631

Query: 325 SRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTM 384
              + +       +  + E     Q +   + L RE++  +L+Q +  + E E+  EQ +
Sbjct: 632 QLLKSEEQEERRQQQLRRE-----QQERREQRLKREEEEERLEQRLKREHEEER-REQEL 685

Query: 385 TQYENQLAALRLE 397
            + E + A  R++
Sbjct: 686 AEEEQEQARERIK 698



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 82/376 (21%), Positives = 148/376 (39%), Gaps = 38/376 (10%)

Query: 98  QKENSILQHKVDETSKKENEEPPCHPVQS--GSYNYQVLNEELSKERAAREALKEVVASA 155
           Q+ +  L  +  E  ++E        +QS  G    +  +EE  + R   E  ++     
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226

Query: 156 ESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAI----ERSHATVKVKEL 211
           +   R  + R+   E + +  K E  + K++ K  E+   R       E     ++ +EL
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286

Query: 212 REQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSF 271
           R + +  EQ  Q    EQ+ R +  + +  +QE+ +                   + +  
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346

Query: 272 RDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAEKDS 331
           R++ +R    E RR  E    +E E   RE ++ +E Q+ R   LR E++LR+ +     
Sbjct: 347 REQQLRREQEEERR--EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ----- 399

Query: 332 FLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQL 391
               L R  Q               L REQ++ + QQ    +RE +   EQ   ++E + 
Sbjct: 400 ---QLRREQQ---------------LRREQQLRREQQL---RREQQLRREQEEERHEQKH 438

Query: 392 AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRALMLERH 451
              R E +RL+      +D    E +TE  +   + + L R++         R L LE  
Sbjct: 439 EQERRE-QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE---EERRERWLKLEEE 494

Query: 452 ERAADLFARMVRARKD 467
           ER      R  + R++
Sbjct: 495 ERREQQERREQQLRRE 510



 Score = 39.5 bits (88), Expect = 0.026
 Identities = 75/357 (21%), Positives = 143/357 (40%), Gaps = 25/357 (7%)

Query: 43  EWKTRNTEFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIKKIERLQKENS 102
           EW+ R T    + E+L        E  + +     E  ++  L+R  + ++ +  +++  
Sbjct: 245 EWRKRETVLRKEEEKLQE------EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298

Query: 103 ILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVA 162
            L+ +     K+E E       Q      Q    E  +ER  ++  +E     E  LR  
Sbjct: 299 RLRREQQLRRKQEEERRE----QQEERREQQERREQQEERREQQLRREQEERREQQLRRE 354

Query: 163 RARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKELREQAETAEQVA 222
           +      E+QL+  + E E  +++ +  +QL     + R     + ++LR + +   +  
Sbjct: 355 QEE-ERREQQLRREQEE-ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412

Query: 223 QSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDME 282
             R  EQ+ R E    +  E+E+ +                   +    R+      + E
Sbjct: 413 LRR--EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470

Query: 283 RRRCLEYVPCKENEPTDR----ETEIWKELQMTRGALLRSE-EELRQSRAEKDSFLNSL- 336
           RR+  +    +E E  +R    E E  +E Q  R   LR E EE R+ R ++      L 
Sbjct: 471 RRK-QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529

Query: 337 SRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ---RENEKSMEQTMTQYENQ 390
            R+   +     Q++   +LL RE++  +L+Q   EQ   RE E+  +Q + + E +
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEER 585



 Score = 39.1 bits (87), Expect = 0.035
 Identities = 64/297 (21%), Positives = 120/297 (40%), Gaps = 16/297 (5%)

Query: 95   ERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVAS 154
            E+L+KE  +LQ + +E  ++E E+      Q   Y  +   E+L +E    + L+E    
Sbjct: 897  EQLRKEQQLLQEEEEELQREEREKRR-RQEQERQYREE---EQLQQEE--EQLLRE---E 947

Query: 155  AESMLRVARARIATLERQLKDTKAEF---EIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
             E   R  R R    +++L+  + +    E  K++ ++ E+        +      ++E 
Sbjct: 948  REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007

Query: 212  REQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSF 271
            RE+    E   Q R  ++  + E  Q    E+EK +                   QL   
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEE-EQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066

Query: 272  RDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRAE--K 329
               + R  ++ER+   E    +E E   RE E  K  +  R    R EEEL+Q   +  +
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLRE-EPEKRRRQERERQCREEEELQQEEEQLLR 1125

Query: 330  DSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQ 386
            +       +  + +  E  + +   E L RE+   + +Q ++ Q   E+ ++Q   Q
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182



 Score = 38.3 bits (85), Expect = 0.060
 Identities = 72/360 (20%), Positives = 142/360 (39%), Gaps = 28/360 (7%)

Query: 84   WLDRDTMIKKIERLQKENSILQHKV--DETSKKENEEPPCHPVQSGSYNYQVLNEELSKE 141
            +L  +  +++ ER Q+       K   +E  ++E EE      Q     +++  +++ ++
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR-QERDRKFRLEEQKVRRQ 1591

Query: 142  RAAREALKEVVA----SAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRL 197
               R+ +++         +  LR  R R    + QL   + E ++ +++ +D + L    
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE-RDRKFLEEEP 1650

Query: 198  AIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXX 257
             + R     +++  R++    E+       EQ+ R +    K  E+E+            
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710

Query: 258  XXXXXXXXXQLQ-SFRDRSIRLVDMER---RRCLEYVPCKENEPTDRETEIWKELQMTRG 313
                     +L+  FR+      + E+   RR   Y    E E    E E  +  +  R 
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770

Query: 314  ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
               R EE+LRQ R E+        ++   E    F+++   E L +E+   + QQ   +Q
Sbjct: 1771 RKFREEEQLRQEREEQ--------QLRSQESDRKFREE---EQLRQER---EEQQLRPQQ 1816

Query: 374  RENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            R+ +   E+   Q E Q   LR E  R R Y    +  +  + + E  +L  + E   R+
Sbjct: 1817 RDGKYRWEEEQLQLEEQEQRLRQE--RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ 1874



 Score = 36.3 bits (80), Expect = 0.24
 Identities = 68/371 (18%), Positives = 147/371 (39%), Gaps = 19/371 (5%)

Query: 84  WLDRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERA 143
           WL  +   ++ ++ ++E  + + + +   ++   +     +Q    + Q L  E  +ER 
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE-QEERR 546

Query: 144 AREALKEVVASAESMLRVARARIATLERQLKDTKAEFE-----IAKKKHKDLEQLVNRLA 198
            +   +E     E   R  R +    ER+ +  K E E     + +++ + LEQ + R  
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606

Query: 199 IERSHATVKVKELREQAETAEQVAQSRV-SEQKARTEFLQAKVAEQEKSKAVAXXXXXXX 257
           +ER     + ++  ++ E  E+  Q  + SE++      Q +  +QE+ +          
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666

Query: 258 XXXXXXXXXQLQSFRDRSIRLVDME--RRRCLEYVPC----KENEPTDRETEIWKELQMT 311
                      +  R++ +   + E  R R    +P      E+E   R+++++   +  
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726

Query: 312 RGALLRSEEELRQSRAEKDSFLNSLSRI-AQGEGTESFQD----KMATELLDREQKIVKL 366
            G   R E+E ++ R E +       R   Q +  E  +D      A E  +R ++ +  
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786

Query: 367 QQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQ 426
           +  + EQRE +   E+   + +  L     + +R R      K++ + E + E L    +
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE-EEEQLQRRER 845

Query: 427 VETLSRERTAL 437
            + L  E   L
Sbjct: 846 AQQLQEEEDGL 856



 Score = 35.5 bits (78), Expect = 0.43
 Identities = 65/311 (20%), Positives = 134/311 (43%), Gaps = 19/311 (6%)

Query: 86   DRDTMIKKIERLQKENS-ILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSK---- 140
            +R+   ++ E LQ+E   +L+ + ++  ++E E       +      Q+L EE  K    
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164

Query: 141  --ERAAREALKEVVASAESMLRVARA-RIATLERQLKDTKA-EFEIAKKKHKDLEQ---L 193
              ER  RE  +E+    E +LR  +  R    ERQ ++ +  + +  K++++D +Q   L
Sbjct: 1165 ELERQYREE-EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDL 1223

Query: 194  VNRLAIERSHATV--KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAX 251
              +   E+ +A    KV     + E   Q+  S++ +++++ + LQ  + EQ++      
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQD-LQHLLGEQQERDREQE 1282

Query: 252  XXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMT 311
                           QL+    +  +  D + +   + +  +E E   R  E  ++ +  
Sbjct: 1283 RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR-EEREEKRRRQETDRKFREE 1341

Query: 312  RGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTID 371
               LL+  EE    R E+D          Q +G +  +++      +RE+K +K +Q + 
Sbjct: 1342 E-QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400

Query: 372  EQRENEKSMEQ 382
             Q E E+ + Q
Sbjct: 1401 CQ-EREQQLRQ 1410


>AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring protein
           AKAP350 protein.
          Length = 3595

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 92/444 (20%), Positives = 185/444 (41%), Gaps = 42/444 (9%)

Query: 50  EFDNDTERLHRMVAGIAENLKAKINFSLEIAKIPWLDRDTMIK----KIERLQKENSILQ 105
           E ++     H+ ++ + E+LKA+I  + E  K   L  +  +     K+E L+KE + + 
Sbjct: 243 EQESKLNEAHKSLSTV-EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVL 301

Query: 106 HKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE-RAAREALKEVVA-----SAESML 159
            ++ E+ + E E      + S       L E+L  E R   E LK+ +        + + 
Sbjct: 302 DRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ 361

Query: 160 RVARARIATLERQLKD--TKAEFEIAK-KKHKDLEQ-LVNRLAIERS---HATVKVKELR 212
                +I T++ +  +  TK    I +  K KDL+Q LVN  + E +   +   K  E+ 
Sbjct: 362 NEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEIL 421

Query: 213 EQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFR 272
            Q E  +   +  V E + +TE L+ ++ E+E                       L+   
Sbjct: 422 RQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 481

Query: 273 DRSIRLVDMERRRCLEYVPCKENEPTDRETEIW-KELQMTRGALLRSEEELRQSRAEKDS 331
                +   ER   L+ +  K  +       +W KE+++    L+   E+L+Q   +   
Sbjct: 482 KIHTPVSQEERLIFLDSIKSKSKD------SVWEKEIEI----LIEENEDLKQQCIQ--- 528

Query: 332 FLNSLSRIAQGEGTESFQDK-MATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQ 390
            LN    I +   T SF +K       + +++   L +  D+  +++   E    +Y+++
Sbjct: 529 -LN--EEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE---LEYKSK 582

Query: 391 LAAL--RLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALI-TAAASRALM 447
           L AL   L ++R+       K   + E +T + +     E + ++ T L+     ++   
Sbjct: 583 LKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREK 642

Query: 448 LERHERAADLFARMVRARKDLAAL 471
           LE  +R +DL  ++ +   +++ L
Sbjct: 643 LELSQRLSDLSEQLKQKHGEISFL 666



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 60/330 (18%), Positives = 137/330 (41%), Gaps = 21/330 (6%)

Query: 109 DETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIAT 168
           ++  K EN       +Q      + LN ++ +E      LK+ + +A+ +L   + +I  
Sbjct: 1   EQDKKVENSNK--EEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 58

Query: 169 LERQLKDTKAEFEIAKKKHKDLEQLVNRL--AIE----RSHATVKVKELREQAETAEQVA 222
             +++K+ K E   +K+K +   + + +L   +E    R+H   + +   +  +  EQ  
Sbjct: 59  KNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFE--TDIVQRMEQET 116

Query: 223 QSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDME 282
           Q ++ + +A  + +  +   Q K + +                    + R  S   V+ +
Sbjct: 117 QRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNED 176

Query: 283 RRRCLEYVPCKEN---EPTDRETEIWKE----LQMTRGALLRSEEELRQSRA-EKDSFLN 334
           + + +     + N   + T+ + E  KE    +   + AL R  E+L +  +  ++    
Sbjct: 177 QIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQR 236

Query: 335 SLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQYENQLAAL 394
           +   IA+ E   +   K  + + D + +IV   ++   ++E E   E  +T Y+ +L  L
Sbjct: 237 ARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASES---RKELELKHEAEVTNYKIKLEML 293

Query: 395 RLEVKRLRNYDCYSKDVSYPELQTEILDLH 424
             E   + +    S++     L+T++L  H
Sbjct: 294 EKEKNAVLDRMAESQEAELERLRTQLLFSH 323



 Score = 40.7 bits (91), Expect = 0.011
 Identities = 80/352 (22%), Positives = 146/352 (41%), Gaps = 31/352 (8%)

Query: 86   DRDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAR 145
            DRD + K+++ L+ +      +  E  +++N E     +       Q L ++L K    R
Sbjct: 1703 DRDDLQKQVKALEIDVEEQVSRFIELEQEKNTE-----LMDLRQQNQALEKQLEK---MR 1754

Query: 146  EALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHAT 205
            + L E     E    V +  I  LE+QLK       I++ + +++EQL N       H  
Sbjct: 1755 KFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLAN-------HLK 1807

Query: 206  VKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXX 265
             K  +  E   + EQ+ Q  + E+    E L+ +V E E++  V+               
Sbjct: 1808 EKTDKCSELLLSKEQL-QRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGA 1866

Query: 266  XQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQS 325
             + +      ++L   ER    + +  KE E T+ E    ++L+  R  L    EE++Q 
Sbjct: 1867 VEAKPELSLEVQL-QAER----DAIDRKEKEITNLE----EQLEQFREELENKNEEVQQL 1917

Query: 326  RAEKD-SFLNSLSRIAQGE-GTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQT 383
              + +     S +R+ + E   + F+D M  E L    K      T D+     K   Q 
Sbjct: 1918 HMQLEIQKKESTTRLQELEQENKLFKDDM--EKLGLAIKESDAMSTQDQHVLFGK-FAQI 1974

Query: 384  MTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEIL-DLHLQVETLSRER 434
            + + E ++  L  +V +L+     + D    E + E++ DL  Q+E L  ++
Sbjct: 1975 IQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQ 2026



 Score = 34.7 bits (76), Expect = 0.75
 Identities = 64/353 (18%), Positives = 141/353 (39%), Gaps = 18/353 (5%)

Query: 92   KKIERLQKENSILQH-KVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
            K +E + + +S L+H KV +T                    + L E L +E  ARE L  
Sbjct: 1544 KLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAV 1603

Query: 151  VVASAESMLRVARARIATLERQLKD-------TKAEFEIAKKKHKDLEQLVNRLAIERSH 203
             ++ AE ++          ERQ+++        + E   A  + ++LE    ++  ER  
Sbjct: 1604 ELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEEREL 1663

Query: 204  ATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXX 263
             + + + ++ +A   EQ  Q     +K   E L+ +   ++    +              
Sbjct: 1664 LSRQKEAMKAEAGPVEQ--QLLQETEKLMKEKLEVQCQAEKDRDDLQKQVKALEIDVEEQ 1721

Query: 264  XXXQLQSFRDRSIRLVDM-ERRRCLEYVPCKENEPTDRET-EIWKELQMTRGALLRSEEE 321
                ++  ++++  L+D+ ++ + LE    K  +  D +  +   E  + +  + + E++
Sbjct: 1722 VSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQ 1781

Query: 322  LRQSRAEKDSFLNSLSRIAQ-GEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSM 380
            L+     +    +    + Q     +   DK +  LL +EQ    LQ+ I E+ E  + +
Sbjct: 1782 LKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQ----LQRDIQERNEEIEKL 1837

Query: 381  EQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRE 433
            E  + + E  L       +++ +   +    + PEL  E+  L  + + + R+
Sbjct: 1838 EFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEV-QLQAERDAIDRK 1889



 Score = 33.1 bits (72), Expect = 2.3
 Identities = 30/133 (22%), Positives = 59/133 (44%), Gaps = 3/133 (2%)

Query: 308  LQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQ 367
            L  ++G  + SE    +S +  DSF   +  + +    E  Q    TE    + +   +Q
Sbjct: 2603 LTHSQGFDIASEGRGEESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQ 2662

Query: 368  QTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQV 427
            Q  +   E  K+   T++  ++ +  ++L+ +    YD      S+ + + E+L L LQ 
Sbjct: 2663 QVSEPWLEERKAYINTISSLKDLITKMQLQ-REAEVYDSSQSHESFSDWRGELL-LALQ- 2719

Query: 428  ETLSRERTALITA 440
            +    ER+ L+ A
Sbjct: 2720 QVFLEERSVLLAA 2732


>AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.
          Length = 1583

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 78/384 (20%), Positives = 170/384 (44%), Gaps = 32/384 (8%)

Query: 96   RLQKENSILQ-HKVDET-SKKE--NEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEV 151
            RL+ +N ++Q  +V +T SK E  NE+  C   +  +    +  +EL   RA    LK+ 
Sbjct: 771  RLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDS 830

Query: 152  VASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKEL 211
            +A + S+     + +  LE ++       E  +K+ K+ E+ +N++ +    A  ++   
Sbjct: 831  LAKSPSVKNDPLSSVKELEEKI-------ENLEKECKEKEEKINKIKLVAVKAKKELDSS 883

Query: 212  REQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXXQLQSF 271
            R++ +T ++  +S  SE+   +  ++  +   E  K +                 + +  
Sbjct: 884  RKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNL----LLEYEKQSEQLDVEKERA 939

Query: 272  RDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSE-EELRQSRAEKD 330
             +   R+ D+ R+     + C+     + +     E   +   LL  +  E+++++A  D
Sbjct: 940  NNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVD 999

Query: 331  SFLNS-----LSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMT 385
              L +       +I +   T +  +++  +L  ++QK  +LQ+T+ E    +K  +QT T
Sbjct: 1000 KELEAEKLQKEQKIKEHATTVNELEELQVQL--QKQK-KQLQKTMQELELVKKDAQQT-T 1055

Query: 386  QYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITAAASRA 445
                ++A     +K L N    +K+    +L+ EI     + ETL  E T+L      ++
Sbjct: 1056 LMNMEIADYERLMKEL-NQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSL------QS 1108

Query: 446  LMLERHERAADLFARMVRARKDLA 469
             + +  E+   +   +V+ +K+LA
Sbjct: 1109 SVQQYEEKNTKIKQLLVKTKKELA 1132



 Score = 39.9 bits (89), Expect = 0.020
 Identities = 61/318 (19%), Positives = 128/318 (40%), Gaps = 19/318 (5%)

Query: 137  ELSKE-RAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVN 195
            EL KE +  +E         +S+LR        L ++L++ ++E E  +    +++    
Sbjct: 709  ELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANE 768

Query: 196  RLAIERSHATVKVKELREQAETAE---QVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXX 252
            +  +E  +  ++V+E+ +    +E   +  +  + E +     L+ K     +++ +   
Sbjct: 769  KTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLK 828

Query: 253  XXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTR 312
                           L S ++   ++ ++E+  C E    K N+      +  KEL  +R
Sbjct: 829  DSLAKSPSVKND--PLSSVKELEEKIENLEKE-CKEKEE-KINKIKLVAVKAKKELDSSR 884

Query: 313  GALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDE 372
                  +EEL   R+EKD    S+  + Q  G ES+++     LL+ E    K  + +D 
Sbjct: 885  KETQTVKEELESLRSEKDQLSASMRDLIQ--GAESYKNL----LLEYE----KQSEQLDV 934

Query: 373  QRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSR 432
            ++E   + E  +     QL    L+ + + N D          LQ+    L +Q+  + R
Sbjct: 935  EKERANNFEHRIEDLTRQLRNSTLQCETI-NSDNEDLLARIETLQSNAKLLEVQILEVQR 993

Query: 433  ERTALITAAASRALMLER 450
             +  +     +  L  E+
Sbjct: 994  AKAMVDKELEAEKLQKEQ 1011



 Score = 33.9 bits (74), Expect = 1.3
 Identities = 72/386 (18%), Positives = 159/386 (41%), Gaps = 40/386 (10%)

Query: 92   KKIERLQKENSILQHKVDET-SKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKE 150
            K+++  +KE   ++ +++   S+K+        +  G+ +Y+ L  E  K+    +  KE
Sbjct: 878  KELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKE 937

Query: 151  VVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKVKE 210
               + E        RI  L RQL+++  + E     ++DL   +  L        V++ E
Sbjct: 938  RANNFEH-------RIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILE 990

Query: 211  L-REQAETAEQV-AQSRVSEQKAR------TEFLQAKVAEQEKSKAVAXXXXXXXXXXXX 262
            + R +A   +++ A+    EQK +       E  + +V  Q++ K +             
Sbjct: 991  VQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKD 1050

Query: 263  XXXXQLQSFRDRSIRLVDMER--RRCLEYVPCKEN--EPTDRETEIWKELQMTRGALLRS 318
                 L      ++ + D ER  +   + +  K N  E  ++E +I K+ Q T    + S
Sbjct: 1051 AQQTTLM-----NMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITS 1105

Query: 319  EEELRQSRAEKDSFLNSL-----SRIAQGEGTES----FQDKMATELLDREQKI----VK 365
             +   Q   EK++ +  L       +A  +  E+     Q  +  EL   +Q++    ++
Sbjct: 1106 LQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQ 1165

Query: 366  LQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
            L +   E+ +  + ++ +  Q++  L+A +  V  L+  +C +       + +E     +
Sbjct: 1166 LAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQE-ECRAAKAEQATVTSEFESYKV 1224

Query: 426  QV-ETLSRERTALITAAASRALMLER 450
            +V   L +++   ++ A +     ER
Sbjct: 1225 RVHNVLKQQKNKSMSQAETEGAKQER 1250


>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
          Length = 1956

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 94/427 (22%), Positives = 172/427 (40%), Gaps = 42/427 (9%)

Query: 23   ESRAGVAAETLGEVRVLSN--LEWKTRN-TEFDNDTERLHRMVAGIAENLKAKINFSLEI 79
            E R   A   L +V  L+N     KT+  +E      RL    A I +  + K NF+ +I
Sbjct: 1275 EERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQI 1334

Query: 80   AKIPW-LDRDT-----MIKKIERLQKENSILQHKVDETSKKENE------EPPCHPVQ-S 126
              +   L+++T     +   +++ Q++  +L+ + +E  + + E      +     VQ  
Sbjct: 1335 EDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWR 1394

Query: 127  GSYNYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKK 186
              Y   V+      E A +E    +  +AE+M  VA AR A+LER     + E   A   
Sbjct: 1395 MKYENNVIQRTEDLEDAKKELAIRLQEAAEAM-GVANARNASLERARHQLQLELGDALSD 1453

Query: 187  HKDLEQLVNRL---AIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQ 243
               +     RL    ++   A    K+  E+++     +Q  V  Q   TE L+ K   +
Sbjct: 1454 LGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEV--QALSTELLKLKNTYE 1511

Query: 244  EKSKAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMER-RRCLEYVPCKENEPTDRET 302
            E                        Q  R+ +  L +ME+ ++ +E          + +T
Sbjct: 1512 ESIVGQETLRRENKNLQEEISNLTNQ-VREGTKNLTEMEKVKKLIE----------EEKT 1560

Query: 303  EIWKELQMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQ- 361
            E+   L+ T GAL R+E ++   +      L  L   A+ E   S +D+       ++Q 
Sbjct: 1561 EVQVTLEETEGALERNESKILHFQ------LELLEAKAELERKLSEKDEEIENFRRKQQC 1614

Query: 362  KIVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEIL 421
             I  LQ ++D + ++   + +   + E  L  + L++    N        S  +LQ +I 
Sbjct: 1615 TIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLS-CANRQVSEATKSLGQLQIQIK 1673

Query: 422  DLHLQVE 428
            DL +Q++
Sbjct: 1674 DLQMQLD 1680



 Score = 35.9 bits (79), Expect = 0.32
 Identities = 80/396 (20%), Positives = 170/396 (42%), Gaps = 31/396 (7%)

Query: 97   LQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSK-ERAAR-------EAL 148
            L+KE   L+  + ++ K++      H V++ +   + LNE++SK  RAA+       + L
Sbjct: 972  LKKEIDDLETMLVKSEKEKRTTE--HKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTL 1029

Query: 149  KEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATVKV 208
             ++    E +  +++A +  LE+Q+ + +   E  +K   + E+ +++L          +
Sbjct: 1030 DDLHMEEEKLSSLSKANL-KLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESM 1088

Query: 209  KELR-EQAETAEQVAQS--RVSEQKARTEFLQAKVAEQEKS-KAVAXXXXXXXXXXXXXX 264
            + L   Q   AE++ +    +S+  ++ E  +  VA+ +K+ K +               
Sbjct: 1089 ENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAER 1148

Query: 265  XXQLQSFRDRSIRLVDM-ERRRCLEYV---PCKENEPTDR-ETEIWKELQMTRGALLRSE 319
              + +  R+R+    D+ +    LE V      + E T + ET+I K  +    A L  E
Sbjct: 1149 TTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFE 1208

Query: 320  EELRQSRAEKDSFLNSLSRI-AQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEK 378
                 S + K    +SL+ +  Q E  +  + K+  +  D + ++  L   +++    + 
Sbjct: 1209 ---TTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKA 1265

Query: 379  SMEQTMTQYENQL--AALRLE-VKRLRNYDCYSKDVSYP---ELQTEILDLHLQVETLSR 432
            + E+  T YE +L  A  +L+ V +L N     K   +    E    + +    +  LSR
Sbjct: 1266 NAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSR 1325

Query: 433  ERTALITAAASRALMLERHERAADLFAR-MVRARKD 467
            E++            LE+  ++    A  + +A++D
Sbjct: 1326 EKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRD 1361


>AB015617-1|BAA88763.1|  948|Homo sapiens ELKS protein.
          Length = 948

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 73/364 (20%), Positives = 153/364 (42%), Gaps = 29/364 (7%)

Query: 98  QKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAAREALKEVVASAES 157
           ++  +ILQ +VD    +  E+     +   +   Q + EE   +      LK+++   E 
Sbjct: 486 EQRAAILQTEVDALRLRLEEKETM--LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 543

Query: 158 MLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNR-----LAIERSHATVK--VKE 210
            + V + +I  L+ QL+D + +    K++ K L+            +E + A  +  ++ 
Sbjct: 544 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIER 603

Query: 211 LREQAETAEQVAQSRVSEQKARTEFLQAKVA--EQEKSKAVAXXXXXXXXXXXXXXXXQL 268
           L+EQ +  E+  Q  +   K   + L+ KV+  + + S+  A                  
Sbjct: 604 LKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLK 663

Query: 269 QSFRDRSIRL-VDMERRRCL--EYVPCKENE---PTDRETEIWKELQMTRGALLRSEEEL 322
           +  R +++ + ++ ++  CL  E    K +E         E+   +Q     + R ++E 
Sbjct: 664 KDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDES 723

Query: 323 RQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQ 382
            +++AE D  L  L  +   E  ++ +DK   EL     + VK Q   +++  N K  EQ
Sbjct: 724 SKAQAEVDRLLEILKEV---ENEKNDKDKKIAELESLTSRQVKDQ---NKKVANLKHKEQ 777

Query: 383 TMTQYENQLAALRLEVKRLR--NYDCYSKDVSYPELQTEILDLHLQVETLSRERTALITA 440
                E + +A  LE  R R  N +  S+ +   EL   +  +  ++E++  + ++   +
Sbjct: 778 V----EKKKSAQMLEEARRREDNLNDSSQQLQVEELLMAMEKVKQELESMKAKLSSTQQS 833

Query: 441 AASR 444
            A +
Sbjct: 834 LAEK 837



 Score = 41.1 bits (92), Expect = 0.009
 Identities = 78/423 (18%), Positives = 175/423 (41%), Gaps = 35/423 (8%)

Query: 87  RDTMIKKI-ERLQKEN---SILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKE- 141
           RD  IKK+ E LQ +       +   + T +    E   H ++S     +  N  L +E 
Sbjct: 305 RDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEM 364

Query: 142 -RAAREALKEVVASA-ESMLRVARARIATLERQLKDTKAEFEIAKK----KHKDLEQLVN 195
            R    A       A ++++ +  ++I+++ER L+D + E ++ K       ++ E+ + 
Sbjct: 365 HRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMK 424

Query: 196 RLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXX 255
           ++ + RSH+     ++ +  +   +   + +   + + E L  + ++ ++   V      
Sbjct: 425 QMEVYRSHSKFMKNKIGQVKQELSR-KDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 483

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDR-ETEIWKEL----QM 310
                      ++ + R R      M  ++  +     E + T   E    K++    + 
Sbjct: 484 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER 543

Query: 311 TRGALLRSEEELRQSRAEKDSFLNSL-SRIAQGEGTESFQDKMATELLDREQKIVKLQQT 369
               L +  E L++   +K+  ++SL  R+   +   +  D   T L   E+ + + ++T
Sbjct: 544 KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL---EEALAEKERT 600

Query: 370 ID---EQRE-NEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
           I+   EQR+ +E+  ++ +  Y+  L  L+ +V  L+       D+S  E +  +LDL  
Sbjct: 601 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG------DLS--EKEASLLDLKE 652

Query: 426 QVETLSRERTALITAAASRALMLERHERAADLFARMVRARKDLAALLDGRIDPPPFEDIA 485
              +L+   + L   +  + L +   ++  +      + +K   A L+ R  P   + I 
Sbjct: 653 HASSLA--SSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQ 710

Query: 486 HAE 488
           H E
Sbjct: 711 HLE 713


>U90028-1|AAB94805.1|  975|Homo sapiens bicaudal-D protein.
          Length = 975

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 52/260 (20%), Positives = 120/260 (46%), Gaps = 18/260 (6%)

Query: 130 NYQVLNEELSKERAAREALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKD 189
           +Y+   E L+KE    E   E + +AE  L V   ++ TL++Q  + +AE++  K+   +
Sbjct: 12  HYKTEIERLTKELT--ETTHEKIQAAEYGLVVLEEKL-TLKQQYDELEAEYDSLKQ---E 65

Query: 190 LEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAV 249
           LEQL  + A  +S +  +  ++ E  ET E+     + E  ++  +   K+ E +     
Sbjct: 66  LEQL--KEAFGQSFSIHR--KVAEDGETREETL---LQESASKEAYYLGKILEMQNELKQ 118

Query: 250 AXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTD-RETEIWKEL 308
           +                 +Q  ++ +  +V+++R R  + +  +E +  + R  + + EL
Sbjct: 119 SRAVVTNVQAENERLTAVVQDLKENN-EMVELQRIRMKDEI--REYKFREARLLQDYTEL 175

Query: 309 QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLD-REQKIVKLQ 367
           +     L +    L+Q++ E +   + + R  +     + Q + A  L +  E ++ +  
Sbjct: 176 EEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEAL 235

Query: 368 QTIDEQRENEKSMEQTMTQY 387
           +T+  +RE + ++ + ++QY
Sbjct: 236 ETLKNEREQKNNLRKELSQY 255



 Score = 36.7 bits (81), Expect = 0.18
 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 4/107 (3%)

Query: 145 REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIA----KKKHKDLEQLVNRLAIE 200
           +EAL E +   +S+L   R +IATL   LK  K   E+A    K K+++ + +V     +
Sbjct: 667 KEALMEEILKLKSLLSTKREQIATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTK 726

Query: 201 RSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSK 247
             +    +KE      +   +  +R  E   + + +Q ++A  E  K
Sbjct: 727 LRNELKALKEDAATFSSLRTMFATRCDEYVTQLDEMQRQLAAAEDEK 773


>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
           containing protein kinase p160ROCK protein.
          Length = 1354

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 60/351 (17%), Positives = 152/351 (43%), Gaps = 38/351 (10%)

Query: 87  RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
           R  +   + +++KE  +LQH+++E  +K  +E         +   + +  E+S  +   E
Sbjct: 474 RRNLESTVSQIEKEKMLLQHRINEYQRKAEQE---------NEKRRNVENEVSTLKDQLE 524

Query: 147 ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
            LK+V  +++    +A  +++ L++QL+    E     +   D    + +   E S +  
Sbjct: 525 DLKKVSQNSQ----LANEKLSQLQKQLE----EANDLLRTESDTAVRLRKSHTEMSKSIS 576

Query: 207 KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX 266
           +++ L  + +   ++ ++  S+       LQA +  + + +                   
Sbjct: 577 QLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQE 636

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
           +++  +  ++  V+ ER+   + +   E E  + E ++  +L+  +    R E+E+ + +
Sbjct: 637 EVKHLK-HNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQ---QRLEQEVNEHK 692

Query: 327 AEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQ 386
             K       +R+   +  +S ++  +  + + E+K       + E+RE  +  E  + Q
Sbjct: 693 VTK-------ARLT--DKHQSIEEAKSVAMCEMEKK-------LKEEREAREKAENRVVQ 736

Query: 387 YENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            E Q + L +++K+ +         +   ++ E+ +L LQ+E  S +R  L
Sbjct: 737 IEKQCSMLDVDLKQSQQ-KLEHLTGNKERMEDEVKNLTLQLEQESNKRLLL 786


>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
           coiled-coil containing protein kinase 1 protein.
          Length = 1354

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 60/351 (17%), Positives = 152/351 (43%), Gaps = 38/351 (10%)

Query: 87  RDTMIKKIERLQKENSILQHKVDETSKKENEEPPCHPVQSGSYNYQVLNEELSKERAARE 146
           R  +   + +++KE  +LQH+++E  +K  +E         +   + +  E+S  +   E
Sbjct: 474 RRNLESTVSQIEKEKMLLQHRINEYQRKAEQE---------NEKRRNVENEVSTLKNQLE 524

Query: 147 ALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQLVNRLAIERSHATV 206
            LK+V  +++    +A  +++ L++QL+    E     +   D    + +   E S +  
Sbjct: 525 DLKKVSQNSQ----LANEKLSQLQKQLE----EANDLLRTESDTAVRLRKSHTEMSKSIS 576

Query: 207 KVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKAVAXXXXXXXXXXXXXXXX 266
           +++ L  + +   ++ ++  S+       LQA +  + + +                   
Sbjct: 577 QLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQE 636

Query: 267 QLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSR 326
           +++  +  ++  V+ ER+   + +   E E  + E ++  +L+  +    R E+E+ + +
Sbjct: 637 EVKHLK-HNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQ---QRLEQEVNEHK 692

Query: 327 AEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQ 386
             K       +R+   +  +S ++  +  + + E+K       + E+RE  +  E  + Q
Sbjct: 693 VTK-------ARLT--DKHQSIEEAKSVAMCEMEKK-------LKEEREAREKAENRVVQ 736

Query: 387 YENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILDLHLQVETLSRERTAL 437
            E Q + L +++K+ +         +   ++ E+ +L LQ+E  S +R  L
Sbjct: 737 IEKQCSMLDVDLKQSQQ-KLEHLTGNKERMEDEVKNLTLQLEQESNKRLLL 786


>BC112273-1|AAI12274.1|  830|Homo sapiens kinesin family member 7
           protein.
          Length = 830

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 26/299 (8%)

Query: 132 QVLNEELSKERAAREALKEVVAS---AESMLRVARARIATLERQLKDTKAEFEIAKKKHK 188
           Q + E     R   E + E+V +   A+++ R    RI  LE++ +  +AE    +++ +
Sbjct: 195 QKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLR 254

Query: 189 DLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
           +LE    + A ERS    +++E R +   A+   Q  + E+K  TE L +  A+ EK   
Sbjct: 255 ELEGKELQDAGERS----RLQEFRRRVAAAQSQVQV-LKEKKQATERLVSLSAQSEK--- 306

Query: 249 VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                             Q Q    R +R  + E++R LE    K      +E E+ K  
Sbjct: 307 -----RLQELERNVQLMRQQQGQLQRRLR-EETEQKRRLEAEMSKRQHRV-KELEL-KHE 358

Query: 309 QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE-QKIVKLQ 367
           Q  +   +++EE     R  +     S+  + Q +  E  Q K     LD+E +K+++ +
Sbjct: 359 QQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEE-QKKW----LDQEMEKVLQQR 413

Query: 368 QTIDEQRENEKSMEQTMTQYENQL-AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
           + ++E  E     E  + + E  +     LE KRLR+    ++D+     + E L+  L
Sbjct: 414 RALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKEL 472


>BC112271-1|AAI12272.1|  830|Homo sapiens kinesin family member 7
           protein.
          Length = 830

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 26/299 (8%)

Query: 132 QVLNEELSKERAAREALKEVVAS---AESMLRVARARIATLERQLKDTKAEFEIAKKKHK 188
           Q + E     R   E + E+V +   A+++ R    RI  LE++ +  +AE    +++ +
Sbjct: 195 QKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLR 254

Query: 189 DLEQLVNRLAIERSHATVKVKELREQAETAEQVAQSRVSEQKARTEFLQAKVAEQEKSKA 248
           +LE    + A ERS    +++E R +   A+   Q  + E+K  TE L +  A+ EK   
Sbjct: 255 ELEGKELQDAGERS----RLQEFRRRVAAAQSQVQV-LKEKKQATERLVSLSAQSEK--- 306

Query: 249 VAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKEL 308
                             Q Q    R +R  + E++R LE    K      +E E+ K  
Sbjct: 307 -----RLQELERNVQLMRQQQGQLQRRLR-EETEQKRRLEAEMSKRQHRV-KELEL-KHE 358

Query: 309 QMTRGALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDRE-QKIVKLQ 367
           Q  +   +++EE     R  +     S+  + Q +  E  Q K     LD+E +K+++ +
Sbjct: 359 QQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEE-QKKW----LDQEMEKVLQQR 413

Query: 368 QTIDEQRENEKSMEQTMTQYENQL-AALRLEVKRLRNYDCYSKDVSYPELQTEILDLHL 425
           + ++E  E     E  + + E  +     LE KRLR+    ++D+     + E L+  L
Sbjct: 414 RALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKEL 472


>BC073744-1|AAH73744.1|  648|Homo sapiens ITSN1 protein protein.
          Length = 648

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 63/262 (24%), Positives = 107/262 (40%), Gaps = 16/262 (6%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR 395
            +  +S  Q +  + NQL  LR
Sbjct: 590 EKETRSKLQEIDIFNNQLKELR 611



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 27/135 (20%), Positives = 55/135 (40%)

Query: 268 LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRA 327
           L+  R    RL  +ER         ++ +   R+ E+ K+L+  R    + EEE R+   
Sbjct: 373 LEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIE 432

Query: 328 EKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQY 387
            +++    L R  Q E   + + ++  +    ++ IV L+          +++     Q 
Sbjct: 433 RREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQL 492

Query: 388 ENQLAALRLEVKRLR 402
           E +L  +R  +   R
Sbjct: 493 EGKLQDIRCRLTTQR 507


>BC058925-1|AAH58925.1|  634|Homo sapiens ITSN1 protein protein.
          Length = 634

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 63/262 (24%), Positives = 107/262 (40%), Gaps = 16/262 (6%)

Query: 141 ERAAREALKEVVASAESMLRVARARIATLER--QLKDTKAEFEIAKKKHKDLE-QLVNRL 197
           ER   E  K   A  E   R  + R+A LER  Q +  +   E  +K+  +LE QL  + 
Sbjct: 359 ERGNLELEKRRQALLEQQ-RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQR 417

Query: 198 AIERSHATVKVKEL-REQAETAEQVAQSRVS-EQKARTEFLQAKVAEQEKSKAVAXXXXX 255
            +ER     + KE+ R +A   E   Q ++  E+  R E L  +  EQE    +      
Sbjct: 418 ELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVL------ 471

Query: 256 XXXXXXXXXXXQLQSFRDRSIRLV-DMERRRCLEYVPCKENEPTDRETEI-WKELQMTRG 313
                      +L++  D+  +L   ++  RC      +E E T++  E+   E+   + 
Sbjct: 472 --KAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQ 529

Query: 314 ALLRSEEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQ 373
            L  S++ L +   EK    + L ++ Q          +   L  +E     L+  +DE 
Sbjct: 530 QLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLDEV 589

Query: 374 RENEKSMEQTMTQYENQLAALR 395
            +  +S  Q +  + NQL  LR
Sbjct: 590 EKETRSKLQEIDIFNNQLKELR 611



 Score = 31.5 bits (68), Expect = 6.9
 Identities = 27/135 (20%), Positives = 55/135 (40%)

Query: 268 LQSFRDRSIRLVDMERRRCLEYVPCKENEPTDRETEIWKELQMTRGALLRSEEELRQSRA 327
           L+  R    RL  +ER         ++ +   R+ E+ K+L+  R    + EEE R+   
Sbjct: 373 LEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIE 432

Query: 328 EKDSFLNSLSRIAQGEGTESFQDKMATELLDREQKIVKLQQTIDEQRENEKSMEQTMTQY 387
            +++    L R  Q E   + + ++  +    ++ IV L+          +++     Q 
Sbjct: 433 RREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQL 492

Query: 388 ENQLAALRLEVKRLR 402
           E +L  +R  +   R
Sbjct: 493 EGKLQDIRCRLTTQR 507


>AY884293-1|AAX84184.1| 1117|Homo sapiens cytospin A protein.
          Length = 1117

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 56/310 (18%), Positives = 127/310 (40%), Gaps = 19/310 (6%)

Query: 135 NEELSKERAA-REALKEVVASAESMLRVARARIATLERQLKDTKAEFEIAKKKHKDLEQ- 192
           NE L +E+    E+L +     E   R      + L+        + ++   ++ +LEQ 
Sbjct: 435 NERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQR 494

Query: 193 ---LVNRLAIERSHATVKVKELREQAETAEQ---VAQSRVSEQKARTEFLQAKVAEQEKS 246
              L      ER       + L    + AEQ    AQ  +   K R+  ++  +  ++K 
Sbjct: 495 YMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKG 554

Query: 247 KAVAXXXXXXXXXXXXXXXXQLQSFRDRSIRLVDMERRRCLE-YVPCKENEPTDRETEIW 305
           KA                  ++   + +    ++ E+++  E Y      + +D +  + 
Sbjct: 555 KAALAATLEEYKATVASDQIEMNRLKAQ----LENEKQKVAELYSIHNSGDKSDIQDLLE 610

Query: 306 K-ELQMTRGALLRS--EEELRQSRAEKDSFLNSLSRIAQGEGTESFQDKMATELLDREQK 362
              L   +   L S  +E+L  +R + +   ++++++   +   +FQ++   ++ D    
Sbjct: 611 SVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVE--DEYRAFQEEAKKQIEDLNMT 668

Query: 363 IVKLQQTIDEQRENEKSMEQTMTQYENQLAALRLEVKRLRNYDCYSKDVSYPELQTEILD 422
           + KL+  +DE+      M++T+ + E+++   R  VK   N      + +  +LQ +  D
Sbjct: 669 LEKLRSDLDEKETERSDMKETIFELEDEVEQHR-AVKLHDNLIISDLENTVKKLQDQKHD 727

Query: 423 LHLQVETLSR 432
           +  +++TL R
Sbjct: 728 MEREIKTLHR 737


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.313    0.127    0.336 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 53,852,856
Number of Sequences: 224733
Number of extensions: 1956861
Number of successful extensions: 16026
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 244
Number of HSP's successfully gapped in prelim test: 1268
Number of HSP's that attempted gapping in prelim test: 11300
Number of HSP's gapped (non-prelim): 4826
length of query: 490
length of database: 73,234,838
effective HSP length: 93
effective length of query: 397
effective length of database: 52,334,669
effective search space: 20776863593
effective search space used: 20776863593
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (22.0 bits)
S2: 67 (31.1 bits)

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