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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001245-TA|BGIBMGA001245-PA|IPR000884|Thrombospondin,
type I, IPR002861|Reeler region, IPR009465|Spondin, N-terminal
         (541 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AK074803-1|BAC11217.1|  807|Homo sapiens protein ( Homo sapiens ...   231   4e-60
AB051390-1|BAB18461.1|  807|Homo sapiens VSGP/F-spondin protein.      231   5e-60
AB018305-1|BAA34482.2|  724|Homo sapiens KIAA0762 protein protein.    231   5e-60
AK074770-1|BAC11196.1|  331|Homo sapiens protein ( Homo sapiens ...   156   2e-37
AB027466-1|BAA85892.1|  331|Homo sapiens spondin 2 protein.           156   2e-37
AC092535-1|AAY40988.1|  331|Homo sapiens unknown protein.             155   3e-37
BC036341-1|AAH36341.1|  331|Homo sapiens spondin 2, extracellula...   155   4e-37
BC002707-1|AAH02707.1|  331|Homo sapiens spondin 2, extracellula...   155   4e-37
AY358948-1|AAQ89307.1|  331|Homo sapiens SPON2 protein.               155   4e-37
AK074618-1|BAC11092.1|  331|Homo sapiens protein ( Homo sapiens ...   155   4e-37
AK024499-1|BAB15789.1|  216|Homo sapiens FLJ00108 protein protein.     81   1e-14
BC041974-1|AAH41974.1|  257|Homo sapiens SPON1 protein protein.        50   2e-05
BC019825-1|AAH19825.1|  259|Homo sapiens SPON1 protein protein.        50   2e-05
AL354919-4|CAM12877.1|  847|Homo sapiens brain-specific angiogen...    47   1e-04
AL354919-1|CAM12874.1| 1466|Homo sapiens brain-specific angiogen...    47   1e-04
BC077726-1|AAH77726.1| 1151|Homo sapiens sema domain, seven thro...    46   4e-04
AB040878-1|BAA95969.1| 1202|Homo sapiens KIAA1445 protein protein.     46   4e-04
X02176-1|CAA26117.1|  559|Homo sapiens protein ( Human mRNA frag...    45   6e-04
BC020721-1|AAH20721.1|  559|Homo sapiens complement component 9 ...    45   6e-04
Y08545-1|CAA69849.1|  533|Homo sapiens complement 9 protein.           45   8e-04
AY358124-1|AAQ88491.1| 1092|Homo sapiens SEMA5B protein.               43   0.003
K02766-1|AAA51889.1|  557|Homo sapiens C9 protein.                     42   0.004
BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase w...    41   0.010
AL354919-7|CAM12879.1| 1500|Homo sapiens brain-specific angiogen...    41   0.010
AL354919-5|CAI16890.1| 1584|Homo sapiens brain-specific angiogen...    41   0.010
AL354919-3|CAM12876.1| 1499|Homo sapiens brain-specific angiogen...    41   0.010
AL354919-2|CAM12875.1| 1554|Homo sapiens brain-specific angiogen...    41   0.010
AB065648-1|BAC05874.1| 1573|Homo sapiens seven transmembrane hel...    41   0.010
AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.     41   0.010
AB005298-1|BAA25362.1| 1572|Homo sapiens BAI 2 protein.                41   0.010
X70872-1|CAA50220.1|  469|Homo sapiens properdin protein.              41   0.013
X57748-1|CAA40914.1|  469|Homo sapiens properdin protein.              41   0.013
M83652-1|AAA36489.1|  469|Homo sapiens complement omponent prope...    41   0.013
BC015756-1|AAH15756.1|  469|Homo sapiens complement factor prope...    41   0.013
AY297813-1|AAP43692.1|  469|Homo sapiens properdin P factor, com...    41   0.013
AF005668-1|AAB62886.1|  469|Homo sapiens properdin protein.            41   0.013
AF005666-1|AAC51626.1|  469|Homo sapiens properdin protein.            41   0.013
AF005665-1|AAB63280.1|  469|Homo sapiens properdin protein.            41   0.013
AL009172-3|CAA15658.1|  454|Homo sapiens complement factor prope...    40   0.029
AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein.     40   0.029
AB051466-1|BAB21770.1| 1536|Homo sapiens KIAA1679 protein protein.     40   0.029
AF542080-1|AAN17826.1| 1156|Homo sapiens cartilage intermediate ...    39   0.039
U52840-1|AAC09473.1| 1074|Homo sapiens semaphorin F homolog prot...    39   0.051
L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein.       39   0.051
BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein.     39   0.051
BC115696-1|AAI15697.1| 1074|Homo sapiens sema domain, seven thro...    39   0.051
AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and ...    38   0.12 
AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.              36   0.36 
AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.        36   0.36 
AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase w...    36   0.36 
AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.        36   0.36 
AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.     36   0.36 
AB005297-1|BAA23647.1| 1584|Homo sapiens BAI 1 protein.                36   0.36 
AB023177-1|BAA76804.2| 1502|Homo sapiens KIAA0960 protein protein.     35   0.63 
X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA...    34   1.5  
BC111720-1|AAI11721.1| 1522|Homo sapiens brain-specific angiogen...    34   1.5  
BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase w...    34   1.5  
AL391807-1|CAI21673.1| 1522|Homo sapiens brain-specific angiogen...    34   1.5  
AL359714-1|CAH71522.1| 1522|Homo sapiens brain-specific angiogen...    34   1.5  
AL356117-1|CAH71772.1| 1522|Homo sapiens brain-specific angiogen...    34   1.5  
AL160401-1|CAH73864.1| 1522|Homo sapiens brain-specific angiogen...    34   1.5  
AL158051-1|CAI19625.1| 1522|Homo sapiens brain-specific angiogen...    34   1.5  
AL133378-1|CAC34969.2| 1522|Homo sapiens brain-specific angiogen...    34   1.5  
AF529821-1|AAM95408.1|  198|Homo sapiens AID protein.                  34   1.5  
AB011122-1|BAA25476.2| 1524|Homo sapiens KIAA0550 protein protein.     34   1.5  
AB005299-1|BAA25363.1| 1522|Homo sapiens BAI 3 protein.                34   1.5  
BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase w...    33   1.9  
AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease disinte...    33   1.9  
DQ318235-1|ABC54570.1|  263|Homo sapiens R-spondin 1 protein.          33   2.6  
DQ165084-1|ABA54597.1|  263|Homo sapiens R-spondin isoform 1 pro...    33   2.6  
BC114966-1|AAI14967.1|  263|Homo sapiens R-spondin homolog (Xeno...    33   2.6  
BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.      33   2.6  
AY183123-1|AAO66337.1|  625|Homo sapiens truncated Rho GTPase-ac...    33   2.6  
AL513220-4|CAI15785.1|  236|Homo sapiens R-spondin homolog (Xeno...    33   2.6  
AL513220-3|CAM12883.1|  263|Homo sapiens R-spondin homolog (Xeno...    33   2.6  
AK131302-1|BAD18470.1|  626|Homo sapiens protein ( Homo sapiens ...    33   2.6  
AF005664-1|AAB63279.1|  160|Homo sapiens properdin protein.            33   2.6  
DQ386730-1|ABD46888.1|  301|Homo sapiens cardiolipin synthase pr...    33   3.4  
BC069010-1|AAH69010.1|  205|Homo sapiens CRLS1 protein protein.        33   3.4  
AL050325-2|CAB65783.4|  234|Homo sapiens R-spondin family, membe...    33   3.4  
AL035461-9|CAB55278.1|  301|Homo sapiens cardiolipin synthase 1 ...    33   3.4  
AF241784-1|AAG44472.1|  301|Homo sapiens CAPTase-iso protein.          33   3.4  
X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for ...    32   4.5  
BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.      32   4.5  
AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.    32   4.5  
AF140674-1|AAD56357.1|  860|Homo sapiens zinc metalloprotease AD...    32   4.5  
AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.        32   4.5  
AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precur...    32   4.5  
AB209717-1|BAD92954.1|  418|Homo sapiens ADAMTS-8 precursor vari...    32   4.5  
AB037158-1|BAA96867.1|  190|Homo sapiens DSCR6a protein.               32   5.9  
DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase w...    31   7.8  
AL138578-1|CAB71238.2|  481|Homo sapiens hypothetical protein pr...    31   7.8  
AL035398-1|CAI22840.1|  481|Homo sapiens protein ( Human DNA seq...    31   7.8  
AL023654-1|CAI21791.1|  481|Homo sapiens protein ( Human DNA seq...    31   7.8  
AK098225-1|BAC05263.1|  236|Homo sapiens protein ( Homo sapiens ...    31   7.8  
AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disinte...    31   7.8  

>AK074803-1|BAC11217.1|  807|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90322 fis, clone NT2RP2001755, highly similar to
           Rattus norvegicus f-spondin mRNA. ).
          Length = 807

 Score =  231 bits (566), Expect = 4e-60
 Identities = 146/439 (33%), Positives = 217/439 (49%), Gaps = 41/439 (9%)

Query: 72  GVFQAYDAQ-TKLHESCAPAVDNATAHPKTEVQVIWNAPLSVRGVCVRLSARVGPT--LT 128
           G FQ  D + T+   +C  AV  +T   +T +QV W AP +  G CV L A +     + 
Sbjct: 112 GTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTG-CVILKASIVQKRIIY 170

Query: 129 ANKWSVLARKICPTSAGPSSLNRQPPIVEPCCACDEAKYEVNFEGMWSRNTHPREFPPEN 188
                 L +K+C   +    +  +P  +  CCAC  AKY + F G WS  THP+++P   
Sbjct: 171 FQDEGSLTKKLCEQDSTFDGVTDKP--ILDCCACGTAKYRLTFYGNWSEKTHPKDYP-RR 227

Query: 189 AHAHFGDIIGASHTAQYRVWQEGRVATTGLRRLADDGSTTALEKELKAESDDIRTIIKAR 248
           A+ H+  IIG SH+  Y +W+ G  A+ G++++A+ GS   +E+E++ +SD++ T+IKA+
Sbjct: 228 AN-HWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAK 286

Query: 249 GI--SWQQLTGTGIPSTFAVFRVDAKHHLVSLAAKLAPSPDWIVGVSALELCNVNCTWRT 306
               +WQ L     PS  A F VD   HL+S    + PSPDW VG+SA +LC   C W  
Sbjct: 287 AQWPAWQPLNVRAAPS--AEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQ 344

Query: 307 SASLSLYPYDAGTDNGISYTSRRMPTIPAAPVRALRT-DWPRDVRSPFFSTT-GEMRPFA 364
                L P+DAGTD+G++Y S   PTIP   +R L + D P   +SPF+    G +   A
Sbjct: 345 KVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHP---QSPFYDPEGGSITQVA 401

Query: 365 RVRLTRLRLYEKSCDVTEPGTDQNV-------QEGVGAGAWCATHGWGPWGPCSVTSGAA 417
           RV + R+    + C++     D  V       ++       C    W PW  CS +S   
Sbjct: 402 RVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACS-SSTCD 460

Query: 418 RASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPAESSGP-CAMSPWS 476
           +  R R  +  A+           D++ C GP   C          ++  GP C MS W 
Sbjct: 461 KGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGP--GC----------SDEDGPTCTMSEWI 508

Query: 477 EWSPCD---GCGVRARTRH 492
            WSPC    G G+R+R R+
Sbjct: 509 TWSPCSISCGMGMRSRERY 527



 Score = 42.7 bits (96), Expect = 0.003
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 22/131 (16%)

Query: 370 RLRLYEKSCDVTEPGTD-QNVQEGVGAGA------WCATHGWGPWGPCSVTSGAARASRQ 422
           R R+ +   D++ P  D Q+ Q  +G G        C    W  W PCS++ G    SR+
Sbjct: 466 RQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGPTCTMSEWITWSPCSISCGMGMRSRE 525

Query: 423 RDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCD 482
           R YV         C +   + + C         V+E E  P+     C M+ W EW    
Sbjct: 526 R-YVKQFPEDGSVCTLPTEETEKC--------TVNE-ECSPSS----CLMTEWGEWDEYS 571

Query: 483 G-CGVRARTRH 492
             CG+  + RH
Sbjct: 572 ATCGMGMKKRH 582



 Score = 40.7 bits (91), Expect = 0.013
 Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 16/94 (17%)

Query: 399 CATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           C    WG W   S T G     R R  +    A    C+ + +  +    P  H      
Sbjct: 559 CLMTEWGEWDEYSATCGMGMKKRHR-MIKMNPADGSMCKAETSQAEKRMMPECH------ 611

Query: 459 YEPDPAESSGPCAMSPWSEWSPCD-GCGVRARTR 491
                   + PC +SPWSEWS C   CG   RTR
Sbjct: 612 --------TIPCLLSPWSEWSDCSVTCGKGMRTR 637


>AB051390-1|BAB18461.1|  807|Homo sapiens VSGP/F-spondin protein.
          Length = 807

 Score =  231 bits (565), Expect = 5e-60
 Identities = 145/438 (33%), Positives = 215/438 (49%), Gaps = 39/438 (8%)

Query: 72  GVFQAYDAQ-TKLHESCAPAVDNATAHPKTEVQVIWNAPLSVRGVCVRLSARVGPT--LT 128
           G FQ  D + T+   +C  AV  +T   +T +QV W AP +  G CV L A +     + 
Sbjct: 112 GTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTG-CVILKASIVQKRIIY 170

Query: 129 ANKWSVLARKICPTSAGPSSLNRQPPIVEPCCACDEAKYEVNFEGMWSRNTHPREFPPEN 188
                 L +K+C   +    +  +P  +  CCAC  AKY + F G WS  THP+++P   
Sbjct: 171 FQDEGSLTKKLCEQDSTFDGVTDKP--ILDCCACGTAKYRLTFYGNWSEKTHPKDYP-RR 227

Query: 189 AHAHFGDIIGASHTAQYRVWQEGRVATTGLRRLADDGSTTALEKELKAESDDIRTIIKAR 248
           A+ H+  IIG SH+  Y +W+ G  A+ G++++A+ GS   +E+E++ +SD++ T+IKA+
Sbjct: 228 AN-HWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAK 286

Query: 249 GI--SWQQLTGTGIPSTFAVFRVDAKHHLVSLAAKLAPSPDWIVGVSALELCNVNCTWRT 306
               +WQ L     PS  A F VD   HL+S    + PSPDW VG+SA +LC   C W  
Sbjct: 287 AQWPAWQPLNVRAAPS--AEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQ 344

Query: 307 SASLSLYPYDAGTDNGISYTSRRMPTIPAAPVRALRT-DWPRDVRSPFFSTT-GEMRPFA 364
                L P+DAGTD+G++Y S   PTIP   +R L + D P   +SPF+    G +   A
Sbjct: 345 KVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHP---QSPFYDPEGGSITQVA 401

Query: 365 RVRLTRLRLYEKSCDVTEPGTDQNV-------QEGVGAGAWCATHGWGPWGPCSVTSGAA 417
           RV + R+    + C++     D  V       ++       C    W PW  CS +S   
Sbjct: 402 RVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACS-SSTCD 460

Query: 418 RASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSE 477
           +  R R  +  A+           D++ C GP       S+      E    C MS W  
Sbjct: 461 KGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGP-----GCSD------EDGSTCTMSEWIT 509

Query: 478 WSPCD---GCGVRARTRH 492
           WSPC    G G+R+R R+
Sbjct: 510 WSPCSISCGMGMRSRERY 527



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 16/94 (17%)

Query: 399 CATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           C    WG W  CS T G     R R  +    A    C+ + +  + C  P  H      
Sbjct: 559 CLMTEWGEWDECSATCGMGMKKRHR-MIKMNPADGSMCKAETSQAEKCMMPECH------ 611

Query: 459 YEPDPAESSGPCAMSPWSEWSPCD-GCGVRARTR 491
                   + PC +SPWSEWS C   CG   RTR
Sbjct: 612 --------TIPCLLSPWSEWSDCSVTCGKGMRTR 637



 Score = 48.0 bits (109), Expect = 8e-05
 Identities = 37/131 (28%), Positives = 55/131 (41%), Gaps = 22/131 (16%)

Query: 370 RLRLYEKSCDVTEPGTD-QNVQEGVGAG------AWCATHGWGPWGPCSVTSGAARASRQ 422
           R R+ +   D++ P  D Q+ Q  +G G      + C    W  W PCS++ G    SR+
Sbjct: 466 RQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRE 525

Query: 423 RDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCD 482
           R YV         C +   + + C         V+E E  P+     C M+ W EW  C 
Sbjct: 526 R-YVKQFPEDGSVCTLPTEEMEKC--------TVNE-ECSPSS----CLMTEWGEWDECS 571

Query: 483 G-CGVRARTRH 492
             CG+  + RH
Sbjct: 572 ATCGMGMKKRH 582


>AB018305-1|BAA34482.2|  724|Homo sapiens KIAA0762 protein protein.
          Length = 724

 Score =  231 bits (565), Expect = 5e-60
 Identities = 145/438 (33%), Positives = 215/438 (49%), Gaps = 39/438 (8%)

Query: 72  GVFQAYDAQ-TKLHESCAPAVDNATAHPKTEVQVIWNAPLSVRGVCVRLSARVGPT--LT 128
           G FQ  D + T+   +C  AV  +T   +T +QV W AP +  G CV L A +     + 
Sbjct: 29  GTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTG-CVILKASIVQKRIIY 87

Query: 129 ANKWSVLARKICPTSAGPSSLNRQPPIVEPCCACDEAKYEVNFEGMWSRNTHPREFPPEN 188
                 L +K+C   +    +  +P  +  CCAC  AKY + F G WS  THP+++P   
Sbjct: 88  FQDEGSLTKKLCEQDSTFDGVTDKP--ILDCCACGTAKYRLTFYGNWSEKTHPKDYP-RR 144

Query: 189 AHAHFGDIIGASHTAQYRVWQEGRVATTGLRRLADDGSTTALEKELKAESDDIRTIIKAR 248
           A+ H+  IIG SH+  Y +W+ G  A+ G++++A+ GS   +E+E++ +SD++ T+IKA+
Sbjct: 145 AN-HWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAK 203

Query: 249 GI--SWQQLTGTGIPSTFAVFRVDAKHHLVSLAAKLAPSPDWIVGVSALELCNVNCTWRT 306
               +WQ L     PS  A F VD   HL+S    + PSPDW VG+SA +LC   C W  
Sbjct: 204 AQWPAWQPLNVRAAPS--AEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQ 261

Query: 307 SASLSLYPYDAGTDNGISYTSRRMPTIPAAPVRALRT-DWPRDVRSPFFSTT-GEMRPFA 364
                L P+DAGTD+G++Y S   PTIP   +R L + D P   +SPF+    G +   A
Sbjct: 262 KVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHP---QSPFYDPEGGSITQVA 318

Query: 365 RVRLTRLRLYEKSCDVTEPGTDQNV-------QEGVGAGAWCATHGWGPWGPCSVTSGAA 417
           RV + R+    + C++     D  V       ++       C    W PW  CS +S   
Sbjct: 319 RVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACS-SSTCD 377

Query: 418 RASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSE 477
           +  R R  +  A+           D++ C GP       S+      E    C MS W  
Sbjct: 378 KGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGP-----GCSD------EDGSTCTMSEWIT 426

Query: 478 WSPCD---GCGVRARTRH 492
           WSPC    G G+R+R R+
Sbjct: 427 WSPCSISCGMGMRSRERY 444



 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 16/94 (17%)

Query: 399 CATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           C    WG W  CS T G     R R  +    A    C+ + +  + C  P  H      
Sbjct: 476 CLMTEWGEWDECSATCGMGMKKRHR-MIKMNPADGSMCKAETSQAEKCMMPECH------ 528

Query: 459 YEPDPAESSGPCAMSPWSEWSPCD-GCGVRARTR 491
                   + PC +SPWSEWS C   CG   RTR
Sbjct: 529 --------TIPCLLSPWSEWSDCSVTCGKGMRTR 554



 Score = 47.6 bits (108), Expect = 1e-04
 Identities = 37/131 (28%), Positives = 55/131 (41%), Gaps = 22/131 (16%)

Query: 370 RLRLYEKSCDVTEPGTD-QNVQEGVGAG------AWCATHGWGPWGPCSVTSGAARASRQ 422
           R R+ +   D++ P  D Q+ Q  +G G      + C    W  W PCS++ G    SR+
Sbjct: 383 RQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRE 442

Query: 423 RDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCD 482
           R YV         C +   + + C         V+E E  P+     C M+ W EW  C 
Sbjct: 443 R-YVKQFPEDGSVCTLPTEETEKC--------TVNE-ECSPSS----CLMTEWGEWDECS 488

Query: 483 G-CGVRARTRH 492
             CG+  + RH
Sbjct: 489 ATCGMGMKKRH 499


>AK074770-1|BAC11196.1|  331|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90289 fis, clone NT2RP1001004, highly similar to
           Spondin 2, extracellular matrix protein. ).
          Length = 331

 Score =  156 bits (378), Expect = 2e-37
 Identities = 86/275 (31%), Positives = 134/275 (48%), Gaps = 11/275 (4%)

Query: 159 CCACDEAKYEVNFEGMWSRNTHPREFPPENAHAHFGDIIGASHTAQYRVWQEGRVATTGL 218
           C A   AKY + F G WS+   P+++P     A +  ++GA+H++ Y +W++ +  + GL
Sbjct: 35  CSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGL 94

Query: 219 RRLADDGSTTALEKELKAESDDIRTIIKARGISWQQLTGTGIPSTFAVFRVDAKHHLVSL 278
           R  A+ G   AL KE++A  + ++++     +       +G   T A   V  +H LVS 
Sbjct: 95  RDFAERGEAWALMKEIEAAGEALQSV---HAVFSAPAVPSGTGQTSAELEVQRRHSLVSF 151

Query: 279 AAKLAPSPDWIVGVSALELCNVNCTWRTSASLSLYPYDAGTDNGISYTSRRMPTIPAAPV 338
             ++ PSPDW VGV +L+LC+ +  WR  A+L LYPYDAGTD+G +++S    TIP   V
Sbjct: 152 VVRIVPSPDWFVGVDSLDLCDGD-RWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTV 210

Query: 339 RALRTDWP-RDVRSPFFSTTGEMRPFARVRLTRLRLYEKSCDVTEPGTDQNVQEGVGAGA 397
             + +  P     S ++     + P ARV L RLR   ++     P       E V + +
Sbjct: 211 TEITSSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIPPAPVLPSRDNEIVDSAS 270

Query: 398 W------CATHGWGPWGPCSVTSGAARASRQRDYV 426
                  C    W  WG C    G      +  YV
Sbjct: 271 VPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV 305


>AB027466-1|BAA85892.1|  331|Homo sapiens spondin 2 protein.
          Length = 331

 Score =  156 bits (378), Expect = 2e-37
 Identities = 86/275 (31%), Positives = 134/275 (48%), Gaps = 11/275 (4%)

Query: 159 CCACDEAKYEVNFEGMWSRNTHPREFPPENAHAHFGDIIGASHTAQYRVWQEGRVATTGL 218
           C A   AKY + F G WS+   P+++P     A +  ++GA+H++ Y +W++ +  + GL
Sbjct: 35  CSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGL 94

Query: 219 RRLADDGSTTALEKELKAESDDIRTIIKARGISWQQLTGTGIPSTFAVFRVDAKHHLVSL 278
           R  A+ G   AL KE++A  + ++++     +       +G   T A   V  +H LVS 
Sbjct: 95  RDFAERGEAWALMKEIEAAGEALQSV---HAVFSAPAVPSGTGQTSAELEVQRRHSLVSF 151

Query: 279 AAKLAPSPDWIVGVSALELCNVNCTWRTSASLSLYPYDAGTDNGISYTSRRMPTIPAAPV 338
             ++ PSPDW VGV +L+LC+ +  WR  A+L LYPYDAGTD+G +++S    TIP   V
Sbjct: 152 VVRIVPSPDWFVGVDSLDLCDGD-RWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTV 210

Query: 339 RALRTDWP-RDVRSPFFSTTGEMRPFARVRLTRLRLYEKSCDVTEPGTDQNVQEGVGAGA 397
             + +  P     S ++     + P ARV L RLR   ++     P       E V + +
Sbjct: 211 TEITSSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIPPAPVLPSRDNEIVDSAS 270

Query: 398 W------CATHGWGPWGPCSVTSGAARASRQRDYV 426
                  C    W  WG C    G      +  YV
Sbjct: 271 VPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV 305


>AC092535-1|AAY40988.1|  331|Homo sapiens unknown protein.
          Length = 331

 Score =  155 bits (377), Expect = 3e-37
 Identities = 90/302 (29%), Positives = 142/302 (47%), Gaps = 12/302 (3%)

Query: 133 SVLARKICPTSAGPSSLNRQPPIVEPCCACDE-AKYEVNFEGMWSRNTHPREFPPENAHA 191
           + L + +C           QP   E  C+    AKY + F G WS+   P+++P     A
Sbjct: 8   AALGKALCALLLATLGAAGQPLGGESICSARALAKYSITFTGKWSQTAFPKQYPLFRPPA 67

Query: 192 HFGDIIGASHTAQYRVWQEGRVATTGLRRLADDGSTTALEKELKAESDDIRTIIKARGIS 251
            +  ++GA+H++ Y +W++ +  + GLR  A+ G   AL KE++A  + ++++     + 
Sbjct: 68  QWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV---HAVF 124

Query: 252 WQQLTGTGIPSTFAVFRVDAKHHLVSLAAKLAPSPDWIVGVSALELCNVNCTWRTSASLS 311
                 +G   T A   V  +H LVS   ++ PSPDW VGV +L+LC+ +  WR  A+L 
Sbjct: 125 SAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGD-RWREQAALD 183

Query: 312 LYPYDAGTDNGISYTSRRMPTIPAAPVRALRTDWP-RDVRSPFFSTTGEMRPFARVRLTR 370
           LYPYDAGTD+G +++S    TIP   V  + +  P     S ++     + P ARV L R
Sbjct: 184 LYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVTLVR 243

Query: 371 LRLYEKSCDVTEPGTDQNVQEGVGAGAW------CATHGWGPWGPCSVTSGAARASRQRD 424
           LR   ++     P       E V + +       C    W  WG C    G      +  
Sbjct: 244 LRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTR 303

Query: 425 YV 426
           YV
Sbjct: 304 YV 305


>BC036341-1|AAH36341.1|  331|Homo sapiens spondin 2, extracellular
           matrix protein protein.
          Length = 331

 Score =  155 bits (376), Expect = 4e-37
 Identities = 88/275 (32%), Positives = 136/275 (49%), Gaps = 11/275 (4%)

Query: 159 CCACDEAKYEVNFEGMWSRNTHPREFPPENAHAHFGDIIGASHTAQYRVWQEGRVATTGL 218
           C A   AKY + F G WS+   P+++P     A +  ++GA+H++ Y +W++ +  + GL
Sbjct: 35  CSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGL 94

Query: 219 RRLADDGSTTALEKELKAESDDIRTIIKARGISWQQLTGTGIPSTFAVFRVDAKHHLVSL 278
           R  A+ G   AL KE++A  + ++++ +         +GTG   T A   V  +H LVS 
Sbjct: 95  RDFAERGEAWALMKEIEAAGEALQSVHEVFSAP-AVPSGTG--QTSAELEVQRRHSLVSF 151

Query: 279 AAKLAPSPDWIVGVSALELCNVNCTWRTSASLSLYPYDAGTDNGISYTSRRMPTIPAAPV 338
             ++ PSPDW VGV +L+LC+ +  WR  A+L LYPYDAGTD+G +++S    TIP   V
Sbjct: 152 VVRIVPSPDWFVGVDSLDLCDGD-RWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTV 210

Query: 339 RALRTDWP-RDVRSPFFSTTGEMRPFARVRLTRLRLYEKSCDVTEPGTDQNVQEGVGAGA 397
             + +  P     S ++     + P ARV L RLR   ++     P       E V + +
Sbjct: 211 TEITSSSPSHPANSFYYPRLKALPPIARVTLLRLRQSPRAFIPPAPVLPSRDNEIVDSAS 270

Query: 398 W------CATHGWGPWGPCSVTSGAARASRQRDYV 426
                  C    W  WG C    G      +  YV
Sbjct: 271 VPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV 305


>BC002707-1|AAH02707.1|  331|Homo sapiens spondin 2, extracellular
           matrix protein protein.
          Length = 331

 Score =  155 bits (376), Expect = 4e-37
 Identities = 88/275 (32%), Positives = 136/275 (49%), Gaps = 11/275 (4%)

Query: 159 CCACDEAKYEVNFEGMWSRNTHPREFPPENAHAHFGDIIGASHTAQYRVWQEGRVATTGL 218
           C A   AKY + F G WS+   P+++P     A +  ++GA+H++ Y +W++ +  + GL
Sbjct: 35  CSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGL 94

Query: 219 RRLADDGSTTALEKELKAESDDIRTIIKARGISWQQLTGTGIPSTFAVFRVDAKHHLVSL 278
           R  A+ G   AL KE++A  + ++++ +         +GTG   T A   V  +H LVS 
Sbjct: 95  RDFAERGEAWALMKEIEAAGEALQSVHEVFSAP-AVPSGTG--QTSAELEVQRRHSLVSF 151

Query: 279 AAKLAPSPDWIVGVSALELCNVNCTWRTSASLSLYPYDAGTDNGISYTSRRMPTIPAAPV 338
             ++ PSPDW VGV +L+LC+ +  WR  A+L LYPYDAGTD+G +++S    TIP   V
Sbjct: 152 VVRIVPSPDWFVGVDSLDLCDGD-RWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTV 210

Query: 339 RALRTDWP-RDVRSPFFSTTGEMRPFARVRLTRLRLYEKSCDVTEPGTDQNVQEGVGAGA 397
             + +  P     S ++     + P ARV L RLR   ++     P       E V + +
Sbjct: 211 TEITSSSPSHPANSFYYPRLKALPPIARVTLLRLRQSPRAFIPPAPVLPSRDNEIVDSAS 270

Query: 398 W------CATHGWGPWGPCSVTSGAARASRQRDYV 426
                  C    W  WG C    G      +  YV
Sbjct: 271 VPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV 305


>AY358948-1|AAQ89307.1|  331|Homo sapiens SPON2 protein.
          Length = 331

 Score =  155 bits (376), Expect = 4e-37
 Identities = 88/275 (32%), Positives = 136/275 (49%), Gaps = 11/275 (4%)

Query: 159 CCACDEAKYEVNFEGMWSRNTHPREFPPENAHAHFGDIIGASHTAQYRVWQEGRVATTGL 218
           C A   AKY + F G WS+   P+++P     A +  ++GA+H++ Y +W++ +  + GL
Sbjct: 35  CSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGL 94

Query: 219 RRLADDGSTTALEKELKAESDDIRTIIKARGISWQQLTGTGIPSTFAVFRVDAKHHLVSL 278
           R  A+ G   AL KE++A  + ++++ +         +GTG   T A   V  +H LVS 
Sbjct: 95  RDFAERGEAWALMKEIEAAGEALQSVHEVFSAP-AVPSGTG--QTSAELEVQRRHSLVSF 151

Query: 279 AAKLAPSPDWIVGVSALELCNVNCTWRTSASLSLYPYDAGTDNGISYTSRRMPTIPAAPV 338
             ++ PSPDW VGV +L+LC+ +  WR  A+L LYPYDAGTD+G +++S    TIP   V
Sbjct: 152 VVRIVPSPDWFVGVDSLDLCDGD-RWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTV 210

Query: 339 RALRTDWP-RDVRSPFFSTTGEMRPFARVRLTRLRLYEKSCDVTEPGTDQNVQEGVGAGA 397
             + +  P     S ++     + P ARV L RLR   ++     P       E V + +
Sbjct: 211 TEITSSSPSHPANSFYYPRLKALPPIARVTLLRLRQSPRAFIPPAPVLPSRDNEIVDSAS 270

Query: 398 W------CATHGWGPWGPCSVTSGAARASRQRDYV 426
                  C    W  WG C    G      +  YV
Sbjct: 271 VPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV 305


>AK074618-1|BAC11092.1|  331|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90137 fis, clone HEMBB1000881, weakly similar to
           Danio rerio mRNA for MINDIN2. ).
          Length = 331

 Score =  155 bits (376), Expect = 4e-37
 Identities = 88/275 (32%), Positives = 136/275 (49%), Gaps = 11/275 (4%)

Query: 159 CCACDEAKYEVNFEGMWSRNTHPREFPPENAHAHFGDIIGASHTAQYRVWQEGRVATTGL 218
           C A   AKY + F G WS+   P+++P     A +  ++GA+H++ Y +W++ +  + GL
Sbjct: 35  CSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGL 94

Query: 219 RRLADDGSTTALEKELKAESDDIRTIIKARGISWQQLTGTGIPSTFAVFRVDAKHHLVSL 278
           R  A+ G   AL KE++A  + ++++ +         +GTG   T A   V  +H LVS 
Sbjct: 95  RDFAERGEAWALMKEIEAAGEALQSVHEVFSAP-AVPSGTG--QTSAELEVQRRHSLVSF 151

Query: 279 AAKLAPSPDWIVGVSALELCNVNCTWRTSASLSLYPYDAGTDNGISYTSRRMPTIPAAPV 338
             ++ PSPDW VGV +L+LC+ +  WR  A+L LYPYDAGTD+G +++S    TIP   V
Sbjct: 152 VVRIVPSPDWFVGVDSLDLCDGD-RWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTV 210

Query: 339 RALRTDWP-RDVRSPFFSTTGEMRPFARVRLTRLRLYEKSCDVTEPGTDQNVQEGVGAGA 397
             + +  P     S ++     + P ARV L RLR   ++     P       E V + +
Sbjct: 211 TEITSSSPSHPANSFYYPRLKALPPIARVTLLRLRQSPRAFIPPAPVLPSRDNEIVDSAS 270

Query: 398 W------CATHGWGPWGPCSVTSGAARASRQRDYV 426
                  C    W  WG C    G      +  YV
Sbjct: 271 VPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV 305


>AK024499-1|BAB15789.1|  216|Homo sapiens FLJ00108 protein protein.
          Length = 216

 Score = 81.0 bits (191), Expect = 1e-14
 Identities = 35/70 (50%), Positives = 47/70 (67%), Gaps = 1/70 (1%)

Query: 265 AVFRVDAKHHLVSLAAKLAPSPDWIVGVSALELCNVNCTWRTSASLSLYPYDAGTDNGIS 324
           A   V  +H LVS   ++ PSPDW VGV +L+LC+ +  WR  A+L LYPYDAGTD+G +
Sbjct: 2   AELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGD-RWREQAALDLYPYDAGTDSGFT 60

Query: 325 YTSRRMPTIP 334
           ++S    TIP
Sbjct: 61  FSSPNFATIP 70


>BC041974-1|AAH41974.1|  257|Homo sapiens SPON1 protein protein.
          Length = 257

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 16/94 (17%)

Query: 399 CATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           C    WG W  CS T G     R R  +    A    C+ + +  + C  P  H      
Sbjct: 9   CLMTEWGEWDECSATCGMGMKKRHR-MIKMNPADGSMCKAETSQAEKCMMPECH------ 61

Query: 459 YEPDPAESSGPCAMSPWSEWSPCD-GCGVRARTR 491
                   + PC +SPWSEWS C   CG   RTR
Sbjct: 62  --------TIPCLLSPWSEWSDCSVTCGKGMRTR 87


>BC019825-1|AAH19825.1|  259|Homo sapiens SPON1 protein protein.
          Length = 259

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 16/94 (17%)

Query: 399 CATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           C    WG W  CS T G     R R  +    A    C+ + +  + C  P  H      
Sbjct: 11  CLMTEWGEWDECSATCGMGMKKRHR-MIKMNPADGSMCKAETSQAEKCMMPECH------ 63

Query: 459 YEPDPAESSGPCAMSPWSEWSPCD-GCGVRARTR 491
                   + PC +SPWSEWS C   CG   RTR
Sbjct: 64  --------TIPCLLSPWSEWSDCSVTCGKGMRTR 89


>AL354919-4|CAM12877.1|  847|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 847

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 59/228 (25%), Positives = 86/228 (37%), Gaps = 42/228 (18%)

Query: 317 AGTDNGISYTSRRMPTIPAAPVRALRTDWPRDVRSP--FFSTTG-----EMRPFARVRLT 369
           +G+ N +  T  R    P    + ++T WPR    P  + + TG     E  P++   LT
Sbjct: 259 SGSSNDLFTTEMRYGEEPEEEPK-VKTQWPRSADEPGLYMAQTGDPAAEEWSPWSVCSLT 317

Query: 370 ---RLRLYEKSCDVTEPGT----DQNVQEGVGAGAWCATHG----WGPWGPCSVT--SGA 416
               L++  +SC  +  GT               A C   G    WGPWGPCS +  +G 
Sbjct: 318 CGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATCPVEGQWLEWGPWGPCSTSCANGT 377

Query: 417 ARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWS 476
            + SR+     PA A    C   LTD + C    + C         PA  S      PW+
Sbjct: 378 QQRSRKCSVAGPAWA---TCTGALTDTREC--SNLEC---------PATDS---KWGPWN 420

Query: 477 EWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAEGPC 523
            WS C   C    + R  +      +   G+       +  PC+E  C
Sbjct: 421 AWSLCSKTCDTGWQRRFRMCQATGTQ---GYPCEGTGEEVKPCSEKRC 465


>AL354919-1|CAM12874.1| 1466|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1466

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 59/228 (25%), Positives = 86/228 (37%), Gaps = 42/228 (18%)

Query: 317 AGTDNGISYTSRRMPTIPAAPVRALRTDWPRDVRSP--FFSTTG-----EMRPFARVRLT 369
           +G+ N +  T  R    P    + ++T WPR    P  + + TG     E  P++   LT
Sbjct: 254 SGSSNDLFTTEMRYGEEPEEEPK-VKTQWPRSADEPGLYMAQTGDPAAEEWSPWSVCSLT 312

Query: 370 ---RLRLYEKSCDVTEPGT----DQNVQEGVGAGAWCATHG----WGPWGPCSVT--SGA 416
               L++  +SC  +  GT               A C   G    WGPWGPCS +  +G 
Sbjct: 313 CGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSATCPVEGQWLEWGPWGPCSTSCANGT 372

Query: 417 ARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWS 476
            + SR+     PA A    C   LTD + C    + C         PA  S      PW+
Sbjct: 373 QQRSRKCSVAGPAWA---TCTGALTDTREC--SNLEC---------PATDS---KWGPWN 415

Query: 477 EWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAEGPC 523
            WS C   C    + R  +      +   G+       +  PC+E  C
Sbjct: 416 AWSLCSKTCDTGWQRRFRMCQATGTQ---GYPCEGTGEEVKPCSEKRC 460


>BC077726-1|AAH77726.1| 1151|Homo sapiens sema domain, seven
           thrombospondin repeats (type 1 and type 1-like),
           transmembra protein.
          Length = 1151

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 19/107 (17%)

Query: 386 DQNVQEGVGAGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKH 445
           D N Q     GAW     W  W PCS + G     R R    PA +  E   + L     
Sbjct: 901 DCNPQACPVRGAWSC---WTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGL----- 952

Query: 446 CHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCDGCGVRARTRH 492
            H     C          A  + P   SPWSEWS C   G ++R+RH
Sbjct: 953 -HTEEALC----------ATQACPEGWSPWSEWSKCTDDGAQSRSRH 988



 Score = 35.1 bits (77), Expect = 0.63
 Identities = 36/133 (27%), Positives = 45/133 (33%), Gaps = 24/133 (18%)

Query: 395 AGAWCATHGWGPWGPCSVTSGAARASRQRDYVWP-ARAHAEACRVQLTDYKHCHGPRMHC 453
           +G W A   WGPW  CS         R+R    P  R     C     +Y+ C+      
Sbjct: 853 SGGWAA---WGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCN------ 903

Query: 454 RAVSEYEPDPAESSGPCAMSPWSEWSPCD-GCG----VRARTRHYLAPRAYKRCHIGFRA 508
                  P      G  A S W+ WSPC   CG     R R+    AP   +   +G   
Sbjct: 904 -------PQACPVRG--AWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHT 954

Query: 509 RTILSQAMPCAEG 521
              L     C EG
Sbjct: 955 EEALCATQACPEG 967



 Score = 33.9 bits (74), Expect = 1.5
 Identities = 29/99 (29%), Positives = 36/99 (36%), Gaps = 19/99 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           GAW     W  W  CS + G     RQR    PA  H           + C G     R 
Sbjct: 665 GAWTP---WSSWALCSTSCGIGFQVRQRSCSNPAPRHGG---------RICVGKSREERF 712

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPCD---GCGVRARTR 491
            +E  P P     P   + W  WS C    G G+++R R
Sbjct: 713 CNENTPCPV----PIFWASWGSWSKCSSNCGGGMQSRRR 747


>AB040878-1|BAA95969.1| 1202|Homo sapiens KIAA1445 protein protein.
          Length = 1202

 Score = 45.6 bits (103), Expect = 4e-04
 Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 19/107 (17%)

Query: 386  DQNVQEGVGAGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKH 445
            D N Q     GAW     W  W PCS + G     R R    PA +  E   + L     
Sbjct: 952  DCNPQACPVRGAWSC---WTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGL----- 1003

Query: 446  CHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCDGCGVRARTRH 492
             H     C          A  + P   SPWSEWS C   G ++R+RH
Sbjct: 1004 -HTEEALC----------ATQACPEGWSPWSEWSKCTDDGAQSRSRH 1039



 Score = 35.1 bits (77), Expect = 0.63
 Identities = 36/133 (27%), Positives = 45/133 (33%), Gaps = 24/133 (18%)

Query: 395  AGAWCATHGWGPWGPCSVTSGAARASRQRDYVWP-ARAHAEACRVQLTDYKHCHGPRMHC 453
            +G W A   WGPW  CS         R+R    P  R     C     +Y+ C+      
Sbjct: 904  SGGWAA---WGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCN------ 954

Query: 454  RAVSEYEPDPAESSGPCAMSPWSEWSPCD-GCG----VRARTRHYLAPRAYKRCHIGFRA 508
                   P      G  A S W+ WSPC   CG     R R+    AP   +   +G   
Sbjct: 955  -------PQACPVRG--AWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHT 1005

Query: 509  RTILSQAMPCAEG 521
               L     C EG
Sbjct: 1006 EEALCATQACPEG 1018



 Score = 33.9 bits (74), Expect = 1.5
 Identities = 29/99 (29%), Positives = 36/99 (36%), Gaps = 19/99 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           GAW     W  W  CS + G     RQR    PA  H           + C G     R 
Sbjct: 716 GAWTP---WSSWALCSTSCGIGFQVRQRSCSNPAPRHGG---------RICVGKSREERF 763

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPCD---GCGVRARTR 491
            +E  P P     P   + W  WS C    G G+++R R
Sbjct: 764 CNENTPCPV----PIFWASWGSWSKCSSNCGGGMQSRRR 798


>X02176-1|CAA26117.1|  559|Homo sapiens protein ( Human mRNA
           fragment for complement component C9. ).
          Length = 559

 Score = 45.2 bits (102), Expect = 6e-04
 Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 10/77 (12%)

Query: 457 SEYEPDPAESSGP-----CAMSPWSEWSPCDGC---GVRARTRHYLAPRAYKRC--HIGF 506
           + Y+P+  ESSG      C MSPWSEWS CD C     R+R+         KRC   +G 
Sbjct: 25  TSYDPELTESSGSASHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGD 84

Query: 507 RARTILSQAMPCAEGPC 523
           R + + ++    AE  C
Sbjct: 85  RRQCVPTEPCEDAEDDC 101


>BC020721-1|AAH20721.1|  559|Homo sapiens complement component 9
           protein.
          Length = 559

 Score = 45.2 bits (102), Expect = 6e-04
 Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 10/77 (12%)

Query: 457 SEYEPDPAESSGP-----CAMSPWSEWSPCDGC---GVRARTRHYLAPRAYKRC--HIGF 506
           + Y+P+  ESSG      C MSPWSEWS CD C     R+R+         KRC   +G 
Sbjct: 25  TSYDPELTESSGSASHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGD 84

Query: 507 RARTILSQAMPCAEGPC 523
           R + + ++    AE  C
Sbjct: 85  RRQCVPTEPCEDAEDDC 101


>Y08545-1|CAA69849.1|  533|Homo sapiens complement 9 protein.
          Length = 533

 Score = 44.8 bits (101), Expect = 8e-04
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 10/75 (13%)

Query: 459 YEPDPAESSGP-----CAMSPWSEWSPCDGC---GVRARTRHYLAPRAYKRC--HIGFRA 508
           Y+P+  ESSG      C MSPWSEWS CD C     R+R+         KRC   +G R 
Sbjct: 1   YDPELTESSGSASHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGDRR 60

Query: 509 RTILSQAMPCAEGPC 523
           + + ++    AE  C
Sbjct: 61  QCVPTEPCEDAEDDC 75


>AY358124-1|AAQ88491.1| 1092|Homo sapiens SEMA5B protein.
          Length = 1092

 Score = 42.7 bits (96), Expect = 0.003
 Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 20/107 (18%)

Query: 386 DQNVQEGVGAGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKH 445
           D N Q     GAW     W  W PCS + G     R R    PA +  E   + L     
Sbjct: 900 DCNPQACPVRGAWSC---WTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGL----- 951

Query: 446 CHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCDGCGVRARTRH 492
            H     C          A  + P   SPWSEWS C   G ++R+RH
Sbjct: 952 -HTEEALC----------ATQACP-GWSPWSEWSKCTDDGAQSRSRH 986



 Score = 32.7 bits (71), Expect = 3.4
 Identities = 31/106 (29%), Positives = 38/106 (35%), Gaps = 22/106 (20%)

Query: 395 AGAWCATHGWGPWGPCSVTSGAARASRQRDYVWP-ARAHAEACRVQLTDYKHCHGPRMHC 453
           +G W A   WGPW  CS         R+R    P  R     C     +Y+ C+      
Sbjct: 852 SGGWAA---WGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCN------ 902

Query: 454 RAVSEYEPDPAESSGPCAMSPWSEWSPCD---GCGVRARTRHYLAP 496
                  P      G  A S W+ WSPC    G G   RTR   +P
Sbjct: 903 -------PQACPVRG--AWSCWTSWSPCSASCGGGHYQRTRSCTSP 939



 Score = 31.5 bits (68), Expect = 7.8
 Identities = 29/99 (29%), Positives = 35/99 (35%), Gaps = 19/99 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           GAW     W  W  CS + G     RQR    PA  H     V         G     R 
Sbjct: 665 GAWTP---WSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRIFV---------GKSREERF 712

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPCD---GCGVRARTR 491
            +E  P P     P   + W  WS C    G G+++R R
Sbjct: 713 CNENTPCPV----PIFWASWGSWSKCSSNCGGGMQSRRR 747


>K02766-1|AAA51889.1|  557|Homo sapiens C9 protein.
          Length = 557

 Score = 42.3 bits (95), Expect = 0.004
 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 10/77 (12%)

Query: 457 SEYEPDPAESSGPCA-----MSPWSEWSPCDGC---GVRARTRHYLAPRAYKRC--HIGF 506
           + Y+P+  ESSG  +     MSPWSEWS CD C     R+R+         KRC   +G 
Sbjct: 24  TSYDPELTESSGSASHIDRRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGD 83

Query: 507 RARTILSQAMPCAEGPC 523
           R + + ++    AE  C
Sbjct: 84  RRQCVPTEPCEDAEDDC 100


>BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase with
            thrombospondin type 1 motif, 9 protein.
          Length = 1935

 Score = 41.1 bits (92), Expect = 0.010
 Identities = 46/171 (26%), Positives = 67/171 (39%), Gaps = 17/171 (9%)

Query: 372  RLYEKSCDV-TEPGTDQNVQEGVGAGAWCATHGWGPWGPCSVTSGAA---RASRQRDYVW 427
            RL ++ CD  T+P + Q  Q+       CA+   GPWG CSVT G     RA +     +
Sbjct: 1085 RLNDRMCDPETKPTSMQTCQQPE-----CASWQAGPWGQCSVTCGQGYQLRAVKCIIGTY 1139

Query: 428  PARAHAEACR--VQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCDG-C 484
             +      C    + TD + C  P  H    +  E   +  S P     +  W+PC   C
Sbjct: 1140 MSVVDDNDCNAATRPTDTQDCELPSCHPPPAAP-ETRRSTYSAPRTQWRFGSWTPCSATC 1198

Query: 485  GVRARTRHYLAPRAYKRCHIGFRARTILSQAM---PCAEGPCEQLVHFSWN 532
            G   R R Y++ R          A   L + +    C+  PC Q     W+
Sbjct: 1199 GKGTRMR-YVSCRDENGSVADESACATLPRPVAKEECSVTPCGQWKALDWS 1248


>AL354919-7|CAM12879.1| 1500|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1500

 Score = 41.1 bits (92), Expect = 0.010
 Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 23/123 (18%)

Query: 404 WGPWGPCSVT--SGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEP 461
           WGPWGPCS +  +G  + SR+     PA A    C   LTD + C    + C        
Sbjct: 373 WGPWGPCSTSCANGTQQRSRKCSVAGPAWA---TCTGALTDTREC--SNLEC-------- 419

Query: 462 DPAESSGPCAMSPWSEWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAE 520
            PA  S      PW+ WS C   C    + R  +      +   G+       +  PC+E
Sbjct: 420 -PATDS---KWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ---GYPCEGTGEEVKPCSE 472

Query: 521 GPC 523
             C
Sbjct: 473 KRC 475


>AL354919-5|CAI16890.1| 1584|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1584

 Score = 41.1 bits (92), Expect = 0.010
 Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 23/123 (18%)

Query: 404 WGPWGPCSVT--SGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEP 461
           WGPWGPCS +  +G  + SR+     PA A    C   LTD + C    + C        
Sbjct: 425 WGPWGPCSTSCANGTQQRSRKCSVAGPAWA---TCTGALTDTREC--SNLEC-------- 471

Query: 462 DPAESSGPCAMSPWSEWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAE 520
            PA  S      PW+ WS C   C    + R  +      +   G+       +  PC+E
Sbjct: 472 -PATDS---KWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ---GYPCEGTGEEVKPCSE 524

Query: 521 GPC 523
             C
Sbjct: 525 KRC 527


>AL354919-3|CAM12876.1| 1499|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1499

 Score = 41.1 bits (92), Expect = 0.010
 Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 23/123 (18%)

Query: 404 WGPWGPCSVT--SGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEP 461
           WGPWGPCS +  +G  + SR+     PA A    C   LTD + C    + C        
Sbjct: 358 WGPWGPCSTSCANGTQQRSRKCSVAGPAWA---TCTGALTDTREC--SNLEC-------- 404

Query: 462 DPAESSGPCAMSPWSEWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAE 520
            PA  S      PW+ WS C   C    + R  +      +   G+       +  PC+E
Sbjct: 405 -PATDS---KWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ---GYPCEGTGEEVKPCSE 457

Query: 521 GPC 523
             C
Sbjct: 458 KRC 460


>AL354919-2|CAM12875.1| 1554|Homo sapiens brain-specific
           angiogenesis inhibitor 2 protein.
          Length = 1554

 Score = 41.1 bits (92), Expect = 0.010
 Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 23/123 (18%)

Query: 404 WGPWGPCSVT--SGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEP 461
           WGPWGPCS +  +G  + SR+     PA A    C   LTD + C    + C        
Sbjct: 413 WGPWGPCSTSCANGTQQRSRKCSVAGPAWA---TCTGALTDTREC--SNLEC-------- 459

Query: 462 DPAESSGPCAMSPWSEWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAE 520
            PA  S      PW+ WS C   C    + R  +      +   G+       +  PC+E
Sbjct: 460 -PATDS---KWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ---GYPCEGTGEEVKPCSE 512

Query: 521 GPC 523
             C
Sbjct: 513 KRC 515


>AB065648-1|BAC05874.1| 1573|Homo sapiens seven transmembrane helix
           receptor protein.
          Length = 1573

 Score = 41.1 bits (92), Expect = 0.010
 Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 23/123 (18%)

Query: 404 WGPWGPCSVT--SGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEP 461
           WGPWGPCS +  +G  + SR+     PA A    C   LTD + C    + C        
Sbjct: 413 WGPWGPCSTSCANGTQQRSRKCSVAGPAWA---TCTGALTDTREC--SNLEC-------- 459

Query: 462 DPAESSGPCAMSPWSEWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAE 520
            PA  S      PW+ WS C   C    + R  +      +   G+       +  PC+E
Sbjct: 460 -PATDS---KWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ---GYPCEGTGEEVKPCSE 512

Query: 521 GPC 523
             C
Sbjct: 513 KRC 515


>AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.
          Length = 1471

 Score = 41.1 bits (92), Expect = 0.010
 Identities = 46/171 (26%), Positives = 67/171 (39%), Gaps = 17/171 (9%)

Query: 372  RLYEKSCDV-TEPGTDQNVQEGVGAGAWCATHGWGPWGPCSVTSGAA---RASRQRDYVW 427
            RL ++ CD  T+P + Q  Q+       CA+   GPWG CSVT G     RA +     +
Sbjct: 927  RLNDRMCDPETKPTSMQTCQQPE-----CASWQAGPWGQCSVTCGQGYQLRAVKCIIGTY 981

Query: 428  PARAHAEACR--VQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCDG-C 484
             +      C    + TD + C  P  H    +  E   +  S P     +  W+PC   C
Sbjct: 982  MSVVDDNDCNAATRPTDTQDCELPSCHPPPAAP-ETRRSTYSAPRTQWRFGSWTPCSATC 1040

Query: 485  GVRARTRHYLAPRAYKRCHIGFRARTILSQAM---PCAEGPCEQLVHFSWN 532
            G   R R Y++ R          A   L + +    C+  PC Q     W+
Sbjct: 1041 GKGTRMR-YVSCRDENGSVADESACATLPRPVAKEECSVTPCGQWKALDWS 1090


>AB005298-1|BAA25362.1| 1572|Homo sapiens BAI 2 protein.
          Length = 1572

 Score = 41.1 bits (92), Expect = 0.010
 Identities = 35/123 (28%), Positives = 48/123 (39%), Gaps = 23/123 (18%)

Query: 404 WGPWGPCSVT--SGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEP 461
           WGPWGPCS +  +G  + SR+     PA A    C   LTD + C    + C        
Sbjct: 413 WGPWGPCSTSCANGTQQRSRKCSVAGPAWA---TCTGALTDTREC--SNLEC-------- 459

Query: 462 DPAESSGPCAMSPWSEWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAE 520
            PA  S      PW+ WS C   C    + R  +      +   G+       +  PC+E
Sbjct: 460 -PATDS---KWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQ---GYPCEGTGEEVKPCSE 512

Query: 521 GPC 523
             C
Sbjct: 513 KRC 515


>X70872-1|CAA50220.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 40.7 bits (91), Expect = 0.013
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W    GWGPW PCSVT      +R+R    P    A  C        HC G      A
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRRRACNHP----APKCG------GHCPGQAQESEA 183

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPC 481
               +  P       A + W  W+PC
Sbjct: 184 CDTQQVCPTHG----AWATWGPWTPC 205



 Score = 39.1 bits (87), Expect = 0.039
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 16/82 (19%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           GWGPWGP   C VT G  +   QR    P   H             C G        +  
Sbjct: 259 GWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGG---------PFCAGDATRTHICNTA 309

Query: 460 EPDPAESSGPCAMSPWSEWSPC 481
            P P +         W EWSPC
Sbjct: 310 VPCPVDGE----WDSWGEWSPC 327



 Score = 34.7 bits (76), Expect = 0.84
 Identities = 41/150 (27%), Positives = 53/150 (35%), Gaps = 26/150 (17%)

Query: 383 PGTDQNVQEGVGAGAWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRV 438
           PG  Q   E       C THG    WGPW PCS +              P    +  C  
Sbjct: 175 PGQAQE-SEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHE-------PKETRSRKCSA 226

Query: 439 QLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMS----PWSEWSPCD-GCG----VRAR 489
                K    P   C  ++ YE        PC ++    PW   SPC   CG    +  R
Sbjct: 227 PEPSQK---PPGKPCPGLA-YEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQR 282

Query: 490 TRHYLAPRAYKRCHIGFRART-ILSQAMPC 518
           T ++  P+       G   RT I + A+PC
Sbjct: 283 TCNHPVPQHGGPFCAGDATRTHICNTAVPC 312


>X57748-1|CAA40914.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 40.7 bits (91), Expect = 0.013
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W    GWGPW PCSVT      +R+R    P    A  C        HC G      A
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRRRACNHP----APKCG------GHCPGQAQESEA 183

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPC 481
               +  P       A + W  W+PC
Sbjct: 184 CDTQQVCPTHG----AWATWGPWTPC 205



 Score = 39.1 bits (87), Expect = 0.039
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 16/82 (19%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           GWGPWGP   C VT G  +   QR    P   H             C G        +  
Sbjct: 259 GWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGG---------PFCAGDATRTHICNTA 309

Query: 460 EPDPAESSGPCAMSPWSEWSPC 481
            P P +         W EWSPC
Sbjct: 310 VPCPVDGE----WDSWGEWSPC 327



 Score = 34.7 bits (76), Expect = 0.84
 Identities = 41/150 (27%), Positives = 53/150 (35%), Gaps = 26/150 (17%)

Query: 383 PGTDQNVQEGVGAGAWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRV 438
           PG  Q   E       C THG    WGPW PCS +              P    +  C  
Sbjct: 175 PGQAQE-SEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHE-------PKETRSRKCSA 226

Query: 439 QLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMS----PWSEWSPCD-GCG----VRAR 489
                K    P   C  ++ YE        PC ++    PW   SPC   CG    +  R
Sbjct: 227 PEPSQK---PPGKPCPGLA-YEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQR 282

Query: 490 TRHYLAPRAYKRCHIGFRART-ILSQAMPC 518
           T ++  P+       G   RT I + A+PC
Sbjct: 283 TCNHPVPQHGGPFCAGDATRTHICNTAVPC 312


>M83652-1|AAA36489.1|  469|Homo sapiens complement omponent
           properdin protein.
          Length = 469

 Score = 40.7 bits (91), Expect = 0.013
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W    GWGPW PCSVT      +R+R    P    A  C        HC G      A
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRRRACNHP----APKCG------GHCPGQAQESEA 183

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPC 481
               +  P       A + W  W+PC
Sbjct: 184 CDTQQVCPTHG----AWATWGPWTPC 205



 Score = 39.1 bits (87), Expect = 0.039
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 16/82 (19%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           GWGPWGP   C VT G  +   QR    P   H             C G        +  
Sbjct: 259 GWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGG---------PFCAGDATRTHICNTA 309

Query: 460 EPDPAESSGPCAMSPWSEWSPC 481
            P P +         W EWSPC
Sbjct: 310 VPCPVDGE----WDSWGEWSPC 327



 Score = 34.7 bits (76), Expect = 0.84
 Identities = 41/150 (27%), Positives = 53/150 (35%), Gaps = 26/150 (17%)

Query: 383 PGTDQNVQEGVGAGAWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRV 438
           PG  Q   E       C THG    WGPW PCS +              P    +  C  
Sbjct: 175 PGQAQE-SEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHE-------PKETRSRKCSA 226

Query: 439 QLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMS----PWSEWSPCD-GCG----VRAR 489
                K    P   C  ++ YE        PC ++    PW   SPC   CG    +  R
Sbjct: 227 PEPSQK---PPGKPCPGLA-YEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQR 282

Query: 490 TRHYLAPRAYKRCHIGFRART-ILSQAMPC 518
           T ++  P+       G   RT I + A+PC
Sbjct: 283 TCNHPVPQHGGPFCAGDATRTHICNTAVPC 312


>BC015756-1|AAH15756.1|  469|Homo sapiens complement factor
           properdin protein.
          Length = 469

 Score = 40.7 bits (91), Expect = 0.013
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W    GWGPW PCSVT      +R+R    P    A  C        HC G      A
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRRRACNHP----APKCG------GHCPGQAQESEA 183

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPC 481
               +  P       A + W  W+PC
Sbjct: 184 CDTQQVCPTHG----AWATWGPWTPC 205



 Score = 39.1 bits (87), Expect = 0.039
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 16/82 (19%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           GWGPWGP   C VT G  +   QR    P   H             C G        +  
Sbjct: 259 GWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGG---------PFCAGDATRTHICNTA 309

Query: 460 EPDPAESSGPCAMSPWSEWSPC 481
            P P +         W EWSPC
Sbjct: 310 VPCPVDGE----WDSWGEWSPC 327



 Score = 34.7 bits (76), Expect = 0.84
 Identities = 41/150 (27%), Positives = 53/150 (35%), Gaps = 26/150 (17%)

Query: 383 PGTDQNVQEGVGAGAWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRV 438
           PG  Q   E       C THG    WGPW PCS +              P    +  C  
Sbjct: 175 PGQAQE-SEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHE-------PKETRSRKCSA 226

Query: 439 QLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMS----PWSEWSPCD-GCG----VRAR 489
                K    P   C  ++ YE        PC ++    PW   SPC   CG    +  R
Sbjct: 227 PEPSQK---PPGKPCPGLA-YEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQR 282

Query: 490 TRHYLAPRAYKRCHIGFRART-ILSQAMPC 518
           T ++  P+       G   RT I + A+PC
Sbjct: 283 TCNHPVPQHGGPFCAGDATRTHICNTAVPC 312


>AY297813-1|AAP43692.1|  469|Homo sapiens properdin P factor,
           complement protein.
          Length = 469

 Score = 40.7 bits (91), Expect = 0.013
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W    GWGPW PCSVT      +R+R    P    A  C        HC G      A
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRRRACNHP----APKCG------GHCPGQAQESEA 183

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPC 481
               +  P       A + W  W+PC
Sbjct: 184 CDTQQVCPTHG----AWATWGPWTPC 205



 Score = 39.1 bits (87), Expect = 0.039
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 16/82 (19%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           GWGPWGP   C VT G  +   QR    P   H             C G        +  
Sbjct: 259 GWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGG---------PFCAGDATRTHICNTA 309

Query: 460 EPDPAESSGPCAMSPWSEWSPC 481
            P P +         W EWSPC
Sbjct: 310 VPCPVDGE----WDSWGEWSPC 327



 Score = 34.7 bits (76), Expect = 0.84
 Identities = 41/150 (27%), Positives = 53/150 (35%), Gaps = 26/150 (17%)

Query: 383 PGTDQNVQEGVGAGAWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRV 438
           PG  Q   E       C THG    WGPW PCS +              P    +  C  
Sbjct: 175 PGQAQE-SEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHE-------PKETRSRKCSA 226

Query: 439 QLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMS----PWSEWSPCD-GCG----VRAR 489
                K    P   C  ++ YE        PC ++    PW   SPC   CG    +  R
Sbjct: 227 PEPSQK---PPGKPCPGLA-YEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQR 282

Query: 490 TRHYLAPRAYKRCHIGFRART-ILSQAMPC 518
           T ++  P+       G   RT I + A+PC
Sbjct: 283 TCNHPVPQHGGPFCAGDATRTHICNTAVPC 312


>AF005668-1|AAB62886.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 40.7 bits (91), Expect = 0.013
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W    GWGPW PCSVT      +R+R    P    A  C        HC G      A
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRRRACNHP----APKCG------GHCPGQAQESEA 183

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPC 481
               +  P       A + W  W+PC
Sbjct: 184 CDTQQVCPTHG----AWATWGPWTPC 205



 Score = 39.1 bits (87), Expect = 0.039
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 16/82 (19%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           GWGPWGP   C VT G  +   QR    P   H             C G        +  
Sbjct: 259 GWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGG---------PFCAGDATRTHICNTA 309

Query: 460 EPDPAESSGPCAMSPWSEWSPC 481
            P P +         W EWSPC
Sbjct: 310 VPCPVDGE----WDSWGEWSPC 327



 Score = 34.7 bits (76), Expect = 0.84
 Identities = 41/150 (27%), Positives = 53/150 (35%), Gaps = 26/150 (17%)

Query: 383 PGTDQNVQEGVGAGAWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRV 438
           PG  Q   E       C THG    WGPW PCS +              P    +  C  
Sbjct: 175 PGQAQE-SEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHE-------PKETRSRKCSA 226

Query: 439 QLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMS----PWSEWSPCD-GCG----VRAR 489
                K    P   C  ++ YE        PC ++    PW   SPC   CG    +  R
Sbjct: 227 PEPSQK---PPGKPCPGLA-YEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQR 282

Query: 490 TRHYLAPRAYKRCHIGFRART-ILSQAMPC 518
           T ++  P+       G   RT I + A+PC
Sbjct: 283 TCNHPVPQHGGPFCAGDATRTHICNTAVPC 312


>AF005666-1|AAC51626.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 40.7 bits (91), Expect = 0.013
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W    GWGPW PCSVT      +R+R    P    A  C        HC G      A
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRRRACNHP----APKCG------GHCPGQAQESEA 183

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPC 481
               +  P       A + W  W+PC
Sbjct: 184 CDTQQVCPTHG----AWATWGPWTPC 205



 Score = 39.1 bits (87), Expect = 0.039
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 16/82 (19%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           GWGPWGP   C VT G  +   QR    P   H             C G        +  
Sbjct: 259 GWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGG---------PFCAGDATRTHICNTA 309

Query: 460 EPDPAESSGPCAMSPWSEWSPC 481
            P P +         W EWSPC
Sbjct: 310 VPCPVDGE----WDSWGEWSPC 327



 Score = 34.7 bits (76), Expect = 0.84
 Identities = 41/150 (27%), Positives = 53/150 (35%), Gaps = 26/150 (17%)

Query: 383 PGTDQNVQEGVGAGAWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRV 438
           PG  Q   E       C THG    WGPW PCS +              P    +  C  
Sbjct: 175 PGQAQE-SEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHE-------PKETRSRKCSA 226

Query: 439 QLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMS----PWSEWSPCD-GCG----VRAR 489
                K    P   C  ++ YE        PC ++    PW   SPC   CG    +  R
Sbjct: 227 PEPSQK---PPGKPCPGLA-YEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQR 282

Query: 490 TRHYLAPRAYKRCHIGFRART-ILSQAMPC 518
           T ++  P+       G   RT I + A+PC
Sbjct: 283 TCNHPVPQHGGPFCAGDATRTHICNTAVPC 312


>AF005665-1|AAB63280.1|  469|Homo sapiens properdin protein.
          Length = 469

 Score = 40.7 bits (91), Expect = 0.013
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W    GWGPW PCSVT      +R+R    P    A  C        HC G      A
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRRRACNHP----APKCG------GHCPGQAQESEA 183

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPC 481
               +  P       A + W  W+PC
Sbjct: 184 CDTQQVCPTHG----AWATWGPWTPC 205



 Score = 39.1 bits (87), Expect = 0.039
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 16/82 (19%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           GWGPWGP   C VT G  +   QR    P   H             C G        +  
Sbjct: 259 GWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGG---------PFCAGDATRTHICNTA 309

Query: 460 EPDPAESSGPCAMSPWSEWSPC 481
            P P +         W EWSPC
Sbjct: 310 VPCPVDGE----WDSWGEWSPC 327



 Score = 34.7 bits (76), Expect = 0.84
 Identities = 41/150 (27%), Positives = 53/150 (35%), Gaps = 26/150 (17%)

Query: 383 PGTDQNVQEGVGAGAWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRV 438
           PG  Q   E       C THG    WGPW PCS +              P    +  C  
Sbjct: 175 PGQAQE-SEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHE-------PKETRSRKCSA 226

Query: 439 QLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMS----PWSEWSPCD-GCG----VRAR 489
                K    P   C  ++ YE        PC ++    PW   SPC   CG    +  R
Sbjct: 227 PEPSQK---PPGKPCPGLA-YEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQR 282

Query: 490 TRHYLAPRAYKRCHIGFRART-ILSQAMPC 518
           T ++  P+       G   RT I + A+PC
Sbjct: 283 TCNHPVPQHGGPFCAGDATRTHICNTAVPC 312


>AL009172-3|CAA15658.1|  454|Homo sapiens complement factor
           properdin protein.
          Length = 454

 Score = 39.5 bits (88), Expect = 0.029
 Identities = 31/106 (29%), Positives = 39/106 (36%), Gaps = 9/106 (8%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRM---H 452
           G W    GWGPW PCSVT      +R+R    PA      C  Q  + + C   ++    
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTS 193

Query: 453 CRAVSEYEPDPAESSGPCAMSPWSE--WSPCDGCGVRARTRHYLAP 496
           C     +EP    S    A  P  +    PC G     R    L P
Sbjct: 194 CHG-GPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPP 238



 Score = 39.1 bits (87), Expect = 0.039
 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 16/82 (19%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           GWGPWGP   C VT G  +   QR    P   H             C G        +  
Sbjct: 244 GWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGG---------PFCAGDATRTHICNTA 294

Query: 460 EPDPAESSGPCAMSPWSEWSPC 481
            P P +         W EWSPC
Sbjct: 295 VPCPVDGE----WDSWGEWSPC 312


>AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein.
          Length = 1322

 Score = 39.5 bits (88), Expect = 0.029
 Identities = 38/116 (32%), Positives = 43/116 (37%), Gaps = 18/116 (15%)

Query: 379 DVTEPGTDQNVQEGVGAGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRV 438
           D   PG      E  G GAW     W PWGPCS T G     R R              +
Sbjct: 686 DCGRPGQVGPSPEEQGCGAWGP---WSPWGPCSRTCGPWGQGRSR----------RCSPL 732

Query: 439 QLTDYKHCHGPRMHCRA-VSEYEPDPAESSGPCAMSPWSEWS-PCDGCGVRARTRH 492
            L   ++C GP    +A  +   P   E S     SPWS  S PC G   R R  H
Sbjct: 733 GLLVLQNCPGPEHQSQACFTAACPVDGEWS---TWSPWSVCSEPCRGTMTRQRQCH 785



 Score = 32.7 bits (71), Expect = 3.4
 Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 1/60 (1%)

Query: 470 CAMSPWSEWSPCDG-CGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAEGPCEQLVH 528
           C  S WS W+ C G CG ++    + +    +    G + R I  +A  C   PCE   H
Sbjct: 918 CGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEGCEH 977


>AB051466-1|BAB21770.1| 1536|Homo sapiens KIAA1679 protein protein.
          Length = 1536

 Score = 39.5 bits (88), Expect = 0.029
 Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 1/49 (2%)

Query: 399  CATHGWGPWGPCSVTSG-AARASRQRDYVWPARAHAEACRVQLTDYKHC 446
            C   GW  W  CS T G   R SR R  + P +     C  +LT  K C
Sbjct: 1178 CQLSGWTAWTECSQTCGHGGRMSRTRFIIMPTQGEGRPCPTELTQEKTC 1226



 Score = 31.9 bits (69), Expect = 5.9
 Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 9/70 (12%)

Query: 468  GPCAMSPWSEWSPCDGCGVRARTRHYLAPRAYKRCHI--GFRARTILSQAM----PCAEG 521
            G C ++ WSEWS C+   +  R+   +  ++  R  I   F  +    Q +    PC  G
Sbjct: 1299 GDCHLTEWSEWSTCELTCIDGRSFETVGRQSRSRTFIIQSFENQDSCPQQVLETRPCTGG 1358

Query: 522  PCEQLVHFSW 531
             C    H++W
Sbjct: 1359 KC---YHYTW 1365



 Score = 31.5 bits (68), Expect = 7.8
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 470 CAMSPWSEWSPC-DGCGVRARTR-HYLAPRAY---KRC-HIGFRARTILSQAMPCAEGPC 523
           C +S WS W  C   CG+  R R  +L  + Y   + C  +  + +  + +A+PC    C
Sbjct: 929 CKLSDWSSWGSCSSSCGIGVRIRSKWLKEKPYNGGRPCPKLDLKNQAQVHEAVPC-YSEC 987

Query: 524 EQLVHFSW 531
            Q   +SW
Sbjct: 988 NQ---YSW 992


>AF542080-1|AAN17826.1| 1156|Homo sapiens cartilage intermediate
           layer protein-like protein CLIP-2 protein.
          Length = 1156

 Score = 39.1 bits (87), Expect = 0.039
 Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 404 WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPR 450
           WGPWGPCS + G  R  R+R    PA    +AC  +  + + C  PR
Sbjct: 152 WGPWGPCSGSCGPGRRLRRRHCPSPA---GDACPGRPLEAQKCVRPR 195


>U52840-1|AAC09473.1| 1074|Homo sapiens semaphorin F homolog
           protein.
          Length = 1074

 Score = 38.7 bits (86), Expect = 0.051
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 19/96 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W     W PW  CS T G     R R    PA A+     + L      H     C  
Sbjct: 842 GVWSC---WSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGL------HTEEALCNT 892

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPCDGCGVRARTR 491
               +P P       + S WS+WS C+  GV+ R R
Sbjct: 893 ----QPCPE------SWSEWSDWSECEASGVQVRAR 918



 Score = 38.3 bits (85), Expect = 0.068
 Identities = 38/122 (31%), Positives = 46/122 (37%), Gaps = 10/122 (8%)

Query: 332 TIPAAPVRALRTDWPRDVRSPFFSTTGEMRPFARVRLTRLRLYEKSCDVTEPGTDQNVQE 391
           +I A P R L  D    V SP+   T          L R R    SCD   P       E
Sbjct: 528 SISACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCRTR----SCDSPAPQCGGWQCE 583

Query: 392 GVGAG-AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAH-AEACRVQLTDYKH 445
           G G   A C+ +G    W  W PCS T G     RQR    P   H    C  Q  + ++
Sbjct: 584 GPGMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERY 643

Query: 446 CH 447
           C+
Sbjct: 644 CN 645


>L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein.
          Length = 1172

 Score = 38.7 bits (86), Expect = 0.051
 Identities = 34/99 (34%), Positives = 41/99 (41%), Gaps = 20/99 (20%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W  +H W PW  CSVT G    +R R    P         V     K+C G     +A
Sbjct: 438 GGW--SH-WSPWSSCSVTCGVGNITRIRLCNSP---------VPQMGGKNCKGSGRETKA 485

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPCD-GC--GVRARTR 491
             +  P P +       SPWS WS C   C  G+R RTR
Sbjct: 486 -CQGAPCPIDG----RWSPWSPWSACTVTCAGGIRERTR 519


>BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein.
          Length = 1172

 Score = 38.7 bits (86), Expect = 0.051
 Identities = 34/99 (34%), Positives = 41/99 (41%), Gaps = 20/99 (20%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W  +H W PW  CSVT G    +R R    P         V     K+C G     +A
Sbjct: 438 GGW--SH-WSPWSSCSVTCGVGNITRIRLCNSP---------VPQMGGKNCKGSGRETKA 485

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPCD-GC--GVRARTR 491
             +  P P +       SPWS WS C   C  G+R RTR
Sbjct: 486 -CQGAPCPIDG----RWSPWSPWSACTVTCAGGIRERTR 519


>BC115696-1|AAI15697.1| 1074|Homo sapiens sema domain, seven
           thrombospondin repeats (type 1 and type 1-like),
           transmembra protein.
          Length = 1074

 Score = 38.7 bits (86), Expect = 0.051
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 19/96 (19%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G W     W PW  CS T G     R R    PA A+     + L      H     C  
Sbjct: 842 GVWSC---WSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGL------HTEEALCNT 892

Query: 456 VSEYEPDPAESSGPCAMSPWSEWSPCDGCGVRARTR 491
               +P P       + S WS+WS C+  GV+ R R
Sbjct: 893 ----QPCPE------SWSEWSDWSECEASGVQVRAR 918



 Score = 38.3 bits (85), Expect = 0.068
 Identities = 38/122 (31%), Positives = 46/122 (37%), Gaps = 10/122 (8%)

Query: 332 TIPAAPVRALRTDWPRDVRSPFFSTTGEMRPFARVRLTRLRLYEKSCDVTEPGTDQNVQE 391
           +I A P R L  D    V SP+   T          L R R    SCD   P       E
Sbjct: 528 SISACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCRTR----SCDSPAPQCGGWQCE 583

Query: 392 GVGAG-AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAH-AEACRVQLTDYKH 445
           G G   A C+ +G    W  W PCS T G     RQR    P   H    C  Q  + ++
Sbjct: 584 GPGMEIANCSRNGGWTPWTSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERY 643

Query: 446 CH 447
           C+
Sbjct: 644 CN 645


>AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and
            metalloprotease with thrombospondin type 1 motifs 9B
            protein.
          Length = 1935

 Score = 37.5 bits (83), Expect = 0.12
 Identities = 45/171 (26%), Positives = 66/171 (38%), Gaps = 17/171 (9%)

Query: 372  RLYEKSCDV-TEPGTDQNVQEGVGAGAWCATHGWGPWGPCSVTSGAA---RASRQRDYVW 427
            RL ++ CD  T+P + Q  Q+       CA+   GPW  CSVT G     RA +     +
Sbjct: 1085 RLNDRMCDPETKPTSMQTCQQPE-----CASWQAGPWVQCSVTCGQGYQLRAVKCIIGTY 1139

Query: 428  PARAHAEACR--VQLTDYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCDG-C 484
             +      C    + TD + C  P  H    +  E   +  S P     +  W+PC   C
Sbjct: 1140 MSVVDDNDCNAATRPTDTQDCELPSCHPPPAAP-ETRRSTYSAPRTQWRFGSWTPCSATC 1198

Query: 485  GVRARTRHYLAPRAYKRCHIGFRARTILSQAM---PCAEGPCEQLVHFSWN 532
            G   R R Y++ R          A   L + +    C+  PC Q     W+
Sbjct: 1199 GKGTRMR-YVSCRDENGSVADESACATLPRPVAKEECSVTPCGQWKALDWS 1248


>AY358886-1|AAQ89245.1|  837|Homo sapiens ADAMTS4 protein.
          Length = 837

 Score = 35.9 bits (79), Expect = 0.36
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 395 AGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCH 447
           AG W     WGPWG CS T G       RD   P  R   + C  + T ++ C+
Sbjct: 520 AGGWGP---WGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCN 570


>AY044847-1|AAL02262.1|  837|Homo sapiens aggrecanase 1 protein.
          Length = 837

 Score = 35.9 bits (79), Expect = 0.36
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 395 AGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCH 447
           AG W     WGPWG CS T G       RD   P  R   + C  + T ++ C+
Sbjct: 520 AGGWGP---WGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCN 570


>AL590714-6|CAH72146.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score = 35.9 bits (79), Expect = 0.36
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 395 AGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCH 447
           AG W     WGPWG CS T G       RD   P  R   + C  + T ++ C+
Sbjct: 520 AGGWGP---WGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCN 570


>AF148213-1|AAD41494.1|  837|Homo sapiens aggrecanase-1 protein.
          Length = 837

 Score = 35.9 bits (79), Expect = 0.36
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 395 AGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCH 447
           AG W     WGPWG CS T G       RD   P  R   + C  + T ++ C+
Sbjct: 520 AGGWGP---WGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCN 570


>AB014588-1|BAA31663.2|  849|Homo sapiens KIAA0688 protein protein.
          Length = 849

 Score = 35.9 bits (79), Expect = 0.36
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 395 AGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCH 447
           AG W     WGPWG CS T G       RD   P  R   + C  + T ++ C+
Sbjct: 532 AGGWGP---WGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCN 582


>AB005297-1|BAA23647.1| 1584|Homo sapiens BAI 1 protein.
          Length = 1584

 Score = 35.9 bits (79), Expect = 0.36
 Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 4/51 (7%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHC 446
           G W A   W  WG CSVT GA    R+R    P    A AC+    +Y+ C
Sbjct: 523 GKWQA---WASWGSCSVTCGAGSQRRERVCSGPFFGGA-ACQGPQDEYRQC 569



 Score = 32.7 bits (71), Expect = 3.4
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 13/98 (13%)

Query: 400 ATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEY 459
           A   W PW  CS T G    +R R  V  + +++  C   L + + C+   + C     +
Sbjct: 356 AAEEWSPWSVCSSTCGEGWQTRTRFCV--SSSYSTQCSGPLREQRLCNNSAV-CPVHGAW 412

Query: 460 EPDPAESSGPCAMSPWSEWSPCDGCGVRARTRHYLAPR 497
           +            SPWS  S   G G R RTR    P+
Sbjct: 413 D----------EWSPWSLCSSTCGRGFRDRTRTCRPPQ 440


>AB023177-1|BAA76804.2| 1502|Homo sapiens KIAA0960 protein protein.
          Length = 1502

 Score = 35.1 bits (77), Expect = 0.63
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 8/58 (13%)

Query: 470 CAMSPWSEWSPCD---GCGVRARTRHYLAPRAYKRCHIGFRARTILSQAMPCAEGPCE 524
           C +S +S WS C    G G++ RTRH +AP  +     G      L++   C   PCE
Sbjct: 40  CIVSEFSAWSECSKTCGSGLQHRTRHVVAPPQF-----GGSGCPNLTEFQVCQSSPCE 92



 Score = 32.7 bits (71), Expect = 3.4
 Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 4/65 (6%)

Query: 470  CAMSPWSEWSPC-DGCGVRAR-TRHYLAPRAYKRCHIGFRARTILSQAMPCAEGPCEQLV 527
            C +S WS WS C   CG+  +  R     + ++    G    +++ Q+ PC   PC +  
Sbjct: 1132 CQLSDWSPWSECSQTCGLTGKMIRRRTVTQPFQ--GDGRPCPSLMDQSKPCPVKPCYRWQ 1189

Query: 528  HFSWN 532
            +  W+
Sbjct: 1190 YGQWS 1194



 Score = 31.5 bits (68), Expect = 7.8
 Identities = 24/87 (27%), Positives = 31/87 (35%), Gaps = 16/87 (18%)

Query: 399 CATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           C    W  W PCS T          D V PA        ++    +   G    C    E
Sbjct: 206 CQVSEWSEWSPCSKTC--------HDMVSPAGTRVRTRTIR----QFPIGSEKECPEFEE 253

Query: 459 YEPDPAESSG--PCAMSPW--SEWSPC 481
            EP  ++  G  PCA   W  +EW+ C
Sbjct: 254 KEPCLSQGDGVVPCATYGWRTTEWTEC 280



 Score = 31.5 bits (68), Expect = 7.8
 Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 5/40 (12%)

Query: 442 DYKHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPC 481
           D K C GP  +   +    P P E    C +SPWS W PC
Sbjct: 335 DLKLCTGPIPNTTQLCHI-PCPTE----CEVSPWSAWGPC 369


>X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA
           -31 to 1139) protein.
          Length = 1170

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 8/86 (9%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           GWGPW P   CSVT G     R R    PA +   + C   +T+ + C+  +  C  +  
Sbjct: 494 GWGPWSPWDICSVTCGGGVQKRSRLCNNPAPQFGGKDCVGDVTENQICN--KQDC-PIDG 550

Query: 459 YEPDPAESSGPCAMSPWSEWSPCDGC 484
              +P  +   C   P   W  C  C
Sbjct: 551 CLSNPCFAGVKCTSYPDGSWK-CGAC 575


>BC111720-1|AAI11721.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 397 AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCH 447
           A C  HG    W PW  CS T G  + +R R    P +     C    T +K C+
Sbjct: 340 ALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT-PPQYGGRPCEGPETHHKPCN 393


>BC063293-1|AAH63293.1|  837|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 4 protein.
          Length = 837

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 4/54 (7%)

Query: 395 AGAWCATHGWGPWGPCSVTSGAARASRQRDYVWP-ARAHAEACRVQLTDYKHCH 447
           AG W     WGPWG CS T G       RD   P  R   + C  +   ++ C+
Sbjct: 520 AGGWGP---WGPWGDCSRTCGGGVQFSSRDCTRPVTRNGGKYCEGRRARFRSCN 570


>AL391807-1|CAI21673.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 397 AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCH 447
           A C  HG    W PW  CS T G  + +R R    P +     C    T +K C+
Sbjct: 340 ALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT-PPQYGGRPCEGPETHHKPCN 393


>AL359714-1|CAH71522.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 397 AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCH 447
           A C  HG    W PW  CS T G  + +R R    P +     C    T +K C+
Sbjct: 340 ALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT-PPQYGGRPCEGPETHHKPCN 393


>AL356117-1|CAH71772.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 397 AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCH 447
           A C  HG    W PW  CS T G  + +R R    P +     C    T +K C+
Sbjct: 340 ALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT-PPQYGGRPCEGPETHHKPCN 393


>AL160401-1|CAH73864.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 397 AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCH 447
           A C  HG    W PW  CS T G  + +R R    P +     C    T +K C+
Sbjct: 340 ALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT-PPQYGGRPCEGPETHHKPCN 393


>AL158051-1|CAI19625.1| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 397 AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCH 447
           A C  HG    W PW  CS T G  + +R R    P +     C    T +K C+
Sbjct: 340 ALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT-PPQYGGRPCEGPETHHKPCN 393


>AL133378-1|CAC34969.2| 1522|Homo sapiens brain-specific
           angiogenesis inhibitor 3 protein.
          Length = 1522

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 397 AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCH 447
           A C  HG    W PW  CS T G  + +R R    P +     C    T +K C+
Sbjct: 340 ALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT-PPQYGGRPCEGPETHHKPCN 393


>AF529821-1|AAM95408.1|  198|Homo sapiens AID protein.
          Length = 198

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 5/40 (12%)

Query: 446 CHGPRMHCRAVSEYEPDPAESSGPCAMSPW-SEWSPCDGC 484
           CH   +  R +S+++PDP    G C    W + WSPC  C
Sbjct: 55  CHVELLFLRYISDWDPDP----GRCYRVTWFTSWSPCYDC 90


>AB011122-1|BAA25476.2| 1524|Homo sapiens KIAA0550 protein protein.
          Length = 1524

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 397 AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCH 447
           A C  HG    W PW  CS T G  + +R R    P +     C    T +K C+
Sbjct: 342 ALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT-PPQYGGRPCEGPETHHKPCN 395


>AB005299-1|BAA25363.1| 1522|Homo sapiens BAI 3 protein.
          Length = 1522

 Score = 33.9 bits (74), Expect = 1.5
 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 397 AWCATHG----WGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCH 447
           A C  HG    W PW  CS T G  + +R R    P +     C    T +K C+
Sbjct: 340 ALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCT-PPQYGGRPCEGPETHHKPCN 393


>BC109114-1|AAI09115.1|  950|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif, 15 protein.
          Length = 950

 Score = 33.5 bits (73), Expect = 1.9
 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 13/73 (17%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G+W     W P+GPCS T G      +R    P  A+           K+C G R+  R+
Sbjct: 517 GSWAK---WDPYGPCSRTCGGGVQLARRQCTNPTPANGG---------KYCEGVRVKYRS 564

Query: 456 VSEYEPDPAESSG 468
            +  EP P+ +SG
Sbjct: 565 CN-LEPCPSSASG 576


>AJ315733-1|CAC86014.1|  950|Homo sapiens metalloprotease
           disintegrin 15 with thrombospondin domains protein.
          Length = 950

 Score = 33.5 bits (73), Expect = 1.9
 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 13/73 (17%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRA 455
           G+W     W P+GPCS T G      +R    P  A+           K+C G R+  R+
Sbjct: 517 GSWAK---WDPYGPCSRTCGGGVQLARRQCTNPTPANGG---------KYCEGVRVKYRS 564

Query: 456 VSEYEPDPAESSG 468
            +  EP P+ +SG
Sbjct: 565 CN-LEPCPSSASG 576


>DQ318235-1|ABC54570.1|  263|Homo sapiens R-spondin 1 protein.
          Length = 263

 Score = 33.1 bits (72), Expect = 2.6
 Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 10/66 (15%)

Query: 466 SSGPCAMSPWSEWSPCDG----CGVR----ARTRHYL-APRA-YKRCHIGFRARTILSQA 515
           S   C MS WS W PC      CG R     RTR  L AP   +  C      R    + 
Sbjct: 144 SPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRR 203

Query: 516 MPCAEG 521
           +PC EG
Sbjct: 204 VPCPEG 209


>DQ165084-1|ABA54597.1|  263|Homo sapiens R-spondin isoform 1
           protein.
          Length = 263

 Score = 33.1 bits (72), Expect = 2.6
 Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 10/66 (15%)

Query: 466 SSGPCAMSPWSEWSPCDG----CGVR----ARTRHYL-APRA-YKRCHIGFRARTILSQA 515
           S   C MS WS W PC      CG R     RTR  L AP   +  C      R    + 
Sbjct: 144 SPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRR 203

Query: 516 MPCAEG 521
           +PC EG
Sbjct: 204 VPCPEG 209


>BC114966-1|AAI14967.1|  263|Homo sapiens R-spondin homolog (Xenopus
           laevis) protein.
          Length = 263

 Score = 33.1 bits (72), Expect = 2.6
 Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 10/66 (15%)

Query: 466 SSGPCAMSPWSEWSPCDG----CGVR----ARTRHYL-APRA-YKRCHIGFRARTILSQA 515
           S   C MS WS W PC      CG R     RTR  L AP   +  C      R    + 
Sbjct: 144 SPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRR 203

Query: 516 MPCAEG 521
           +PC EG
Sbjct: 204 VPCPEG 209


>BC089435-1|AAH89435.1|  918|Homo sapiens ADAMTS8 protein protein.
          Length = 918

 Score = 33.1 bits (72), Expect = 2.6
 Identities = 18/56 (32%), Positives = 22/56 (39%), Gaps = 4/56 (7%)

Query: 393 VGAGAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAH-AEACRVQLTDYKHCH 447
           V  G W     WGPWG CS T G       R+   P   +    C  +   Y+ CH
Sbjct: 553 VADGGWAP---WGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCH 605


>AY183123-1|AAO66337.1|  625|Homo sapiens truncated Rho
           GTPase-activating protein 4 splice form 2 protein.
          Length = 625

 Score = 33.1 bits (72), Expect = 2.6
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 5/61 (8%)

Query: 148 SLNRQPPIVEPCCACDEAKYEVNFEGMWSRNTHPREFPPENAHAHFGDIIGASHTAQYRV 207
           +LN + P+VE C A D        + ++ R+  P  FPP+     FG+++ +S T  +R 
Sbjct: 532 NLNGEDPLVEGCTAHDLDSVAGVLK-LYFRSLEPPLFPPDL----FGELLASSGTPSWRA 586

Query: 208 W 208
           W
Sbjct: 587 W 587


>AL513220-4|CAI15785.1|  236|Homo sapiens R-spondin homolog (Xenopus
           laevis) protein.
          Length = 236

 Score = 33.1 bits (72), Expect = 2.6
 Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 10/66 (15%)

Query: 466 SSGPCAMSPWSEWSPCDG----CGVR----ARTRHYL-APRA-YKRCHIGFRARTILSQA 515
           S   C MS WS W PC      CG R     RTR  L AP   +  C      R    + 
Sbjct: 117 SPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRR 176

Query: 516 MPCAEG 521
           +PC EG
Sbjct: 177 VPCPEG 182


>AL513220-3|CAM12883.1|  263|Homo sapiens R-spondin homolog (Xenopus
           laevis) protein.
          Length = 263

 Score = 33.1 bits (72), Expect = 2.6
 Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 10/66 (15%)

Query: 466 SSGPCAMSPWSEWSPCDG----CGVR----ARTRHYL-APRA-YKRCHIGFRARTILSQA 515
           S   C MS WS W PC      CG R     RTR  L AP   +  C      R    + 
Sbjct: 144 SPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRR 203

Query: 516 MPCAEG 521
           +PC EG
Sbjct: 204 VPCPEG 209


>AK131302-1|BAD18470.1|  626|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16275 fis, clone NT2RI2027157, moderately
           similar to Mouse SDR2 mRNA. ).
          Length = 626

 Score = 33.1 bits (72), Expect = 2.6
 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 4/46 (8%)

Query: 70  PLGVFQAYDAQTKLHESC----APAVDNATAHPKTEVQVIWNAPLS 111
           P+G F   D++     +C      AV + +A  KTE++V WNAP S
Sbjct: 90  PIGSFTLIDSEVSQLLTCEDIQGSAVSHRSASKKTEIKVYWNAPSS 135


>AF005664-1|AAB63279.1|  160|Homo sapiens properdin protein.
          Length = 160

 Score = 33.1 bits (72), Expect = 2.6
 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 3/27 (11%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQ 422
           G W    GWGPW PCSVT      +R+
Sbjct: 137 GGWS---GWGPWEPCSVTCSKGTRTRR 160


>DQ386730-1|ABD46888.1|  301|Homo sapiens cardiolipin synthase
           protein.
          Length = 301

 Score = 32.7 bits (71), Expect = 3.4
 Identities = 12/33 (36%), Positives = 16/33 (48%)

Query: 448 GPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSP 480
           G R HC    +  P PA  +G  A +P  +W P
Sbjct: 64  GQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGP 96


>BC069010-1|AAH69010.1|  205|Homo sapiens CRLS1 protein protein.
          Length = 205

 Score = 32.7 bits (71), Expect = 3.4
 Identities = 12/33 (36%), Positives = 16/33 (48%)

Query: 448 GPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSP 480
           G R HC    +  P PA  +G  A +P  +W P
Sbjct: 64  GQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGP 96


>AL050325-2|CAB65783.4|  234|Homo sapiens R-spondin family, member 4
           protein.
          Length = 234

 Score = 32.7 bits (71), Expect = 3.4
 Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 4/63 (6%)

Query: 465 ESSGPCAMSPWSEWSPCDGCGVRARTRHYLAPRAYKRCHIGF-RART--ILSQAMPC-AE 520
           E  G C + PW  WSPC   G    +   L  R  +    G   A T  +LS++  C  +
Sbjct: 134 ECQGECELGPWGGWSPCTHNGKTCGSAWGLESRVREAGRAGHEEAATCQVLSESRKCPIQ 193

Query: 521 GPC 523
            PC
Sbjct: 194 RPC 196


>AL035461-9|CAB55278.1|  301|Homo sapiens cardiolipin synthase 1
           protein.
          Length = 301

 Score = 32.7 bits (71), Expect = 3.4
 Identities = 12/33 (36%), Positives = 16/33 (48%)

Query: 448 GPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSP 480
           G R HC    +  P PA  +G  A +P  +W P
Sbjct: 64  GQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGP 96


>AF241784-1|AAG44472.1|  301|Homo sapiens CAPTase-iso protein.
          Length = 301

 Score = 32.7 bits (71), Expect = 3.4
 Identities = 12/33 (36%), Positives = 16/33 (48%)

Query: 448 GPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSP 480
           G R HC    +  P PA  +G  A +P  +W P
Sbjct: 64  GQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGP 96


>X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for
           thrombospondin. ).
          Length = 1170

 Score = 32.3 bits (70), Expect = 4.5
 Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 8/86 (9%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           GWGPW P   CSVT G     R R    P  +   + C   +T+ + C+  +  C  +  
Sbjct: 494 GWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICN--KQDC-PIDG 550

Query: 459 YEPDPAESSGPCAMSPWSEWSPCDGC 484
              +P  +   C   P   W  C  C
Sbjct: 551 CLSNPCFAGVKCTSYPDGSWK-CGAC 575


>BC113874-1|AAI13875.1|  676|Homo sapiens ADAMTS8 protein protein.
          Length = 676

 Score = 32.3 bits (70), Expect = 4.5
 Identities = 17/53 (32%), Positives = 21/53 (39%), Gaps = 4/53 (7%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAH-AEACRVQLTDYKHCH 447
           G W     WGPWG CS T G       R+   P   +    C  +   Y+ CH
Sbjct: 314 GGWAP---WGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCH 363


>AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.
          Length = 1117

 Score = 32.3 bits (70), Expect = 4.5
 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 4/97 (4%)

Query: 403 GWGPW---GPCSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           GWGPW   G CS T G   +S  R    PA     + C  +   Y+ C+       +   
Sbjct: 560 GWGPWSLWGECSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPLGSRDF 619

Query: 459 YEPDPAESSGPCAMSPWSEWSPCDGCGVRARTRHYLA 495
            E   A+         +  W P  G GV+    + LA
Sbjct: 620 REKQCADFDNMPFRGKYYNWKPYTGGGVKPCALNCLA 656


>AF140674-1|AAD56357.1|  860|Homo sapiens zinc metalloprotease
           ADAMTS6 protein.
          Length = 860

 Score = 32.3 bits (70), Expect = 4.5
 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 4/97 (4%)

Query: 403 GWGPW---GPCSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           GWGPW   G CS T G   +S  R    PA     + C  +   Y+ C+       +   
Sbjct: 512 GWGPWSLWGECSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPLGSRDF 571

Query: 459 YEPDPAESSGPCAMSPWSEWSPCDGCGVRARTRHYLA 495
            E   A+         +  W P  G GV+    + LA
Sbjct: 572 REKQCADFDNMPFRGKYYNWKPYTGGGVKPCALNCLA 608


>AF060153-1|AAD48081.1|  890|Homo sapiens METH2 protein protein.
          Length = 890

 Score = 32.3 bits (70), Expect = 4.5
 Identities = 17/53 (32%), Positives = 21/53 (39%), Gaps = 4/53 (7%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAH-AEACRVQLTDYKHCH 447
           G W     WGPWG CS T G       R+   P   +    C  +   Y+ CH
Sbjct: 528 GGWAP---WGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCH 577


>AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precursor
           variant protein.
          Length = 1225

 Score = 32.3 bits (70), Expect = 4.5
 Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 8/86 (9%)

Query: 403 GWGPWGP---CSVTSGAARASRQRDYVWPA-RAHAEACRVQLTDYKHCHGPRMHCRAVSE 458
           GWGPW P   CSVT G     R R    P  +   + C   +T+ + C+  +  C  +  
Sbjct: 549 GWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICN--KQDC-PIDG 605

Query: 459 YEPDPAESSGPCAMSPWSEWSPCDGC 484
              +P  +   C   P   W  C  C
Sbjct: 606 CLSNPCFAGVKCTSYPDGSWK-CGAC 630


>AB209717-1|BAD92954.1|  418|Homo sapiens ADAMTS-8 precursor variant
           protein.
          Length = 418

 Score = 32.3 bits (70), Expect = 4.5
 Identities = 17/53 (32%), Positives = 21/53 (39%), Gaps = 4/53 (7%)

Query: 396 GAWCATHGWGPWGPCSVTSGAARASRQRDYVWPARAH-AEACRVQLTDYKHCH 447
           G W     WGPWG CS T G       R+   P   +    C  +   Y+ CH
Sbjct: 56  GGWAP---WGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCH 105


>AB037158-1|BAA96867.1|  190|Homo sapiens DSCR6a protein.
          Length = 190

 Score = 31.9 bits (69), Expect = 5.9
 Identities = 17/55 (30%), Positives = 22/55 (40%), Gaps = 2/55 (3%)

Query: 444 KHCHGPRMHCRAVSEYEPDPAESSGPCAMSPWSEWSPCDGCGVRARTRHYLAPRA 498
           +   G   HC   + + P P    GP + +PW  W    G     RT   L PRA
Sbjct: 10  RKARGRGCHCPGDAPWRPPPPR--GPESPAPWRPWIQTPGDAELTRTGRPLEPRA 62


>DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase with
           thrombospondin type 1 motif 17 protein.
          Length = 1095

 Score = 31.5 bits (68), Expect = 7.8
 Identities = 31/108 (28%), Positives = 38/108 (35%), Gaps = 16/108 (14%)

Query: 405 GPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPA 464
           GPW PCS T       R+   V+  +         L    +C GPR    AV   E    
Sbjct: 868 GPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPL----YCPGPRP--AAVQSCE---- 917

Query: 465 ESSGPCAMSPW--SEWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRAR 509
              G   +S W  SEWS C   CG     R      +  +C    R R
Sbjct: 918 ---GQDCLSIWEASEWSQCSASCGKGVWKRTVACTNSQGKCDASTRPR 962


>AL138578-1|CAB71238.2|  481|Homo sapiens hypothetical protein
           protein.
          Length = 481

 Score = 31.5 bits (68), Expect = 7.8
 Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 1/47 (2%)

Query: 461 PDPAESSGPCAMSP-WSEWSPCDGCGVRARTRHYLAPRAYKRCHIGF 506
           P  ++ + PC     W  W+PC   G  A T+    PR+  R  + F
Sbjct: 410 PVSSQQASPCTPEQDWPCWTPCSPKGCPAETKAEATPRSILRSSLNF 456


>AL035398-1|CAI22840.1|  481|Homo sapiens protein ( Human DNA
           sequence from clone RP4-796I17 on chromosome
           22q13.2-35.1.).
          Length = 481

 Score = 31.5 bits (68), Expect = 7.8
 Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 1/47 (2%)

Query: 461 PDPAESSGPCAMSP-WSEWSPCDGCGVRARTRHYLAPRAYKRCHIGF 506
           P  ++ + PC     W  W+PC   G  A T+    PR+  R  + F
Sbjct: 410 PVSSQQASPCTPEQDWPCWTPCSPKGCPAETKAEATPRSILRSSLNF 456


>AL023654-1|CAI21791.1|  481|Homo sapiens protein ( Human DNA
           sequence from clone RP4-549K18 on chromosome
           22q13.1-13.32.  ).
          Length = 481

 Score = 31.5 bits (68), Expect = 7.8
 Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 1/47 (2%)

Query: 461 PDPAESSGPCAMSP-WSEWSPCDGCGVRARTRHYLAPRAYKRCHIGF 506
           P  ++ + PC     W  W+PC   G  A T+    PR+  R  + F
Sbjct: 410 PVSSQQASPCTPEQDWPCWTPCSPKGCPAETKAEATPRSILRSSLNF 456


>AK098225-1|BAC05263.1|  236|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40906 fis, clone UTERU2004698, highly similar to
           Mus musculus mRNA for thrombospondin type 1 domain. ).
          Length = 236

 Score = 31.5 bits (68), Expect = 7.8
 Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 10/66 (15%)

Query: 466 SSGPCAMSPWSEWSPCDG----CGVR----ARTRHYL-APRA-YKRCHIGFRARTILSQA 515
           S   C +S WS W PC      CG R     RTR  L AP   +  C      R    + 
Sbjct: 117 SPAQCEVSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRR 176

Query: 516 MPCAEG 521
           +PC EG
Sbjct: 177 VPCPEG 182


>AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease
           disintegrin 17, with thrombospondin domains protein.
          Length = 1095

 Score = 31.5 bits (68), Expect = 7.8
 Identities = 31/108 (28%), Positives = 38/108 (35%), Gaps = 16/108 (14%)

Query: 405 GPWGPCSVTSGAARASRQRDYVWPARAHAEACRVQLTDYKHCHGPRMHCRAVSEYEPDPA 464
           GPW PCS T       R+   V+  +         L    +C GPR    AV   E    
Sbjct: 868 GPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPL----YCPGPRP--AAVQSCE---- 917

Query: 465 ESSGPCAMSPW--SEWSPCD-GCGVRARTRHYLAPRAYKRCHIGFRAR 509
              G   +S W  SEWS C   CG     R      +  +C    R R
Sbjct: 918 ---GQDCLSIWEASEWSQCSASCGKGVWKRTVACTNSQGKCDASTRPR 962


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.319    0.132    0.434 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 88,278,488
Number of Sequences: 224733
Number of extensions: 3847230
Number of successful extensions: 8534
Number of sequences better than 10.0: 96
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 8067
Number of HSP's gapped (non-prelim): 393
length of query: 541
length of database: 73,234,838
effective HSP length: 94
effective length of query: 447
effective length of database: 52,109,936
effective search space: 23293141392
effective search space used: 23293141392
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)

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