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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001244-TA|BGIBMGA001244-PA|IPR008376|Synembryn
         (493 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC121808-1|AAI21809.1|  530|Homo sapiens RIC8A protein protein.       192   2e-48
BC121807-1|AAI21808.1|  530|Homo sapiens RIC8A protein protein.       192   2e-48
BC111499-1|AAI11500.1|  530|Homo sapiens RIC8A protein protein.       192   2e-48
BC011821-1|AAH11821.2|  467|Homo sapiens RIC8A protein protein.       192   2e-48
AL390088-1|CAB98211.1|  531|Homo sapiens hypothetical protein, s...   190   1e-47
AK027461-1|BAB55126.1|  421|Homo sapiens protein ( Homo sapiens ...   190   1e-47
BX538115-1|CAD98025.1|  525|Homo sapiens hypothetical protein pr...   190   1e-47
BC034220-1|AAH34220.1|  496|Homo sapiens RIC8B protein protein.       189   2e-47
AK001482-1|BAA91717.1|  536|Homo sapiens protein ( Homo sapiens ...   189   2e-47
AY221116-1|AAO65923.1|  513|Homo sapiens brain synembryn protein.     188   5e-47
BC132689-1|AAI32690.1|  520|Homo sapiens resistance to inhibitor...   157   8e-38
AK027090-1|BAB15653.1|  272|Homo sapiens protein ( Homo sapiens ...   149   2e-35
AK022870-1|BAB14282.1|  291|Homo sapiens protein ( Homo sapiens ...   113   2e-24
AK128102-1|BAC87276.1|  258|Homo sapiens protein ( Homo sapiens ...   107   1e-22

>BC121808-1|AAI21809.1|  530|Homo sapiens RIC8A protein protein.
          Length = 530

 Score =  192 bits (469), Expect = 2e-48
 Identities = 128/423 (30%), Positives = 215/423 (50%), Gaps = 25/423 (5%)

Query: 63  EVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKICKHIPYKKELMQYDMKLIFIL 122
           +V +E++KCLCN+  +S +A+ +    R+   L  R+ + +   +  ++  +D++L+F+L
Sbjct: 112 DVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLL 171

Query: 123 TALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEASVSANSEDAPKYYFTDEDRVI 182
           TAL  ++R +   E   + ++       +++L     E ++    E  P      ++   
Sbjct: 172 TALRTDVRQQLFQELKGVRLL-------TDTL-----ELTLGVTPEGNPPTLLPSQETER 219

Query: 183 VCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIMTVQTSSKSNDLDLMNNIVNL 242
             E+ K LFN I L +      E++   + +L ++L   + + T+    + +   + VNL
Sbjct: 220 AMEILKVLFN-ITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTE-EFHGHAVNL 277

Query: 243 LTSI--HTLFYMSLTEEIGDKQKPDHIYEGRDMTSLVILLQFLKHQLTASDERQNLYEKL 300
           L ++    L  +   E  GD  +    + G +M  +  LL FL+ +L    +   L E +
Sbjct: 278 LGNLPLKCLDVLLTLEPHGDSTE----FMGVNMDVIRALLIFLEKRL---HKTHRLKESV 330

Query: 301 SPILTVLNKCARV-RVQRKFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDL 359
           +P+L+VL +CAR+ R  RKFL+  VLP LRDV   PE G+ LRN L RL+T   T V+ +
Sbjct: 331 APVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRV 390

Query: 360 VAEFLFVLCKEKVSRMVKYTGFGNXXXXXXXXXXXXXXX-XXXYXXXXXXXXXXYRRHAH 418
            AEFLFVLC E V R +KYTG+GN                   Y          Y+    
Sbjct: 391 AAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKA 450

Query: 419 ALDPVVGCTRPPPADPFRGMTDEQKEYEAMKLVNLFDKMVTAGVVKPARVGADGQLQAVE 478
           +++PV G     P +P  GMT+EQKE+EAMKLV +FDK+    V++P  +   G L +++
Sbjct: 451 SINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQ 510

Query: 479 HVL 481
             +
Sbjct: 511 DAM 513


>BC121807-1|AAI21808.1|  530|Homo sapiens RIC8A protein protein.
          Length = 530

 Score =  192 bits (469), Expect = 2e-48
 Identities = 128/423 (30%), Positives = 215/423 (50%), Gaps = 25/423 (5%)

Query: 63  EVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKICKHIPYKKELMQYDMKLIFIL 122
           +V +E++KCLCN+  +S +A+ +    R+   L  R+ + +   +  ++  +D++L+F+L
Sbjct: 112 DVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLL 171

Query: 123 TALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEASVSANSEDAPKYYFTDEDRVI 182
           TAL  ++R +   E   + ++       +++L     E ++    E  P      ++   
Sbjct: 172 TALRTDVRQQLFQELKGVRLL-------TDTL-----ELTLGVTPEGNPPTLLPSQETER 219

Query: 183 VCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIMTVQTSSKSNDLDLMNNIVNL 242
             E+ K LFN I L +      E++   + +L ++L   + + T+    + +   + VNL
Sbjct: 220 AMEILKVLFN-ITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTE-EFHGHAVNL 277

Query: 243 LTSI--HTLFYMSLTEEIGDKQKPDHIYEGRDMTSLVILLQFLKHQLTASDERQNLYEKL 300
           L ++    L  +   E  GD  +    + G +M  +  LL FL+ +L    +   L E +
Sbjct: 278 LGNLPLKCLDVLLTLEPHGDSTE----FMGVNMDVIRALLIFLEKRL---HKTHRLKESV 330

Query: 301 SPILTVLNKCARV-RVQRKFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDL 359
           +P+L+VL +CAR+ R  RKFL+  VLP LRDV   PE G+ LRN L RL+T   T V+ +
Sbjct: 331 APVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRV 390

Query: 360 VAEFLFVLCKEKVSRMVKYTGFGNXXXXXXXXXXXXXXX-XXXYXXXXXXXXXXYRRHAH 418
            AEFLFVLC E V R +KYTG+GN                   Y          Y+    
Sbjct: 391 AAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKA 450

Query: 419 ALDPVVGCTRPPPADPFRGMTDEQKEYEAMKLVNLFDKMVTAGVVKPARVGADGQLQAVE 478
           +++PV G     P +P  GMT+EQKE+EAMKLV +FDK+    V++P  +   G L +++
Sbjct: 451 SINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQ 510

Query: 479 HVL 481
             +
Sbjct: 511 DAM 513


>BC111499-1|AAI11500.1|  530|Homo sapiens RIC8A protein protein.
          Length = 530

 Score =  192 bits (469), Expect = 2e-48
 Identities = 128/423 (30%), Positives = 215/423 (50%), Gaps = 25/423 (5%)

Query: 63  EVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKICKHIPYKKELMQYDMKLIFIL 122
           +V +E++KCLCN+  +S +A+ +    R+   L  R+ + +   +  ++  +D++L+F+L
Sbjct: 112 DVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLL 171

Query: 123 TALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEASVSANSEDAPKYYFTDEDRVI 182
           TAL  ++R +   E   + ++       +++L     E ++    E  P      ++   
Sbjct: 172 TALRTDVRQQLFQELKGVRLL-------TDTL-----ELTLGVTPEGNPPTLLPSQETER 219

Query: 183 VCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIMTVQTSSKSNDLDLMNNIVNL 242
             E+ K LFN I L +      E++   + +L ++L   + + T+    + +   + VNL
Sbjct: 220 AMEILKVLFN-ITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTE-EFHGHAVNL 277

Query: 243 LTSI--HTLFYMSLTEEIGDKQKPDHIYEGRDMTSLVILLQFLKHQLTASDERQNLYEKL 300
           L ++    L  +   E  GD  +    + G +M  +  LL FL+ +L    +   L E +
Sbjct: 278 LGNLPLKCLDVLLTLEPHGDSTE----FMGVNMDVIRALLIFLEKRL---HKTHRLKESV 330

Query: 301 SPILTVLNKCARV-RVQRKFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDL 359
           +P+L+VL +CAR+ R  RKFL+  VLP LRDV   PE G+ LRN L RL+T   T V+ +
Sbjct: 331 APVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRV 390

Query: 360 VAEFLFVLCKEKVSRMVKYTGFGNXXXXXXXXXXXXXXX-XXXYXXXXXXXXXXYRRHAH 418
            AEFLFVLC E V R +KYTG+GN                   Y          Y+    
Sbjct: 391 AAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKA 450

Query: 419 ALDPVVGCTRPPPADPFRGMTDEQKEYEAMKLVNLFDKMVTAGVVKPARVGADGQLQAVE 478
           +++PV G     P +P  GMT+EQKE+EAMKLV +FDK+    V++P  +   G L +++
Sbjct: 451 SINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQ 510

Query: 479 HVL 481
             +
Sbjct: 511 DAM 513


>BC011821-1|AAH11821.2|  467|Homo sapiens RIC8A protein protein.
          Length = 467

 Score =  192 bits (469), Expect = 2e-48
 Identities = 128/423 (30%), Positives = 215/423 (50%), Gaps = 25/423 (5%)

Query: 63  EVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKICKHIPYKKELMQYDMKLIFIL 122
           +V +E++KCLCN+  +S +A+ +    R+   L  R+ + +   +  ++  +D++L+F+L
Sbjct: 49  DVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLL 108

Query: 123 TALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEASVSANSEDAPKYYFTDEDRVI 182
           TAL  ++R +   E   + ++       +++L     E ++    E  P      ++   
Sbjct: 109 TALRTDVRQQLFQELKGVRLL-------TDTL-----ELTLGVTPEGNPPTLLPSQETER 156

Query: 183 VCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIMTVQTSSKSNDLDLMNNIVNL 242
             E+ K LFN I L +      E++   + +L ++L   + + T+    + +   + VNL
Sbjct: 157 AMEILKVLFN-ITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTE-EFHGHAVNL 214

Query: 243 LTSI--HTLFYMSLTEEIGDKQKPDHIYEGRDMTSLVILLQFLKHQLTASDERQNLYEKL 300
           L ++    L  +   E  GD  +    + G +M  +  LL FL+ +L    +   L E +
Sbjct: 215 LGNLPLKCLDVLLTLEPHGDSTE----FMGVNMDVIRALLIFLEKRL---HKTHRLKESV 267

Query: 301 SPILTVLNKCARV-RVQRKFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDL 359
           +P+L+VL +CAR+ R  RKFL+  VLP LRDV   PE G+ LRN L RL+T   T V+ +
Sbjct: 268 APVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRV 327

Query: 360 VAEFLFVLCKEKVSRMVKYTGFGNXXXXXXXXXXXXXXX-XXXYXXXXXXXXXXYRRHAH 418
            AEFLFVLC E V R +KYTG+GN                   Y          Y+    
Sbjct: 328 AAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKA 387

Query: 419 ALDPVVGCTRPPPADPFRGMTDEQKEYEAMKLVNLFDKMVTAGVVKPARVGADGQLQAVE 478
           +++PV G     P +P  GMT+EQKE+EAMKLV +FDK+    V++P  +   G L +++
Sbjct: 388 SINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQ 447

Query: 479 HVL 481
             +
Sbjct: 448 DAM 450


>AL390088-1|CAB98211.1|  531|Homo sapiens hypothetical protein,
           similar to AK001482(BAA91717.1) [Homo sapiens] protein.
          Length = 531

 Score =  190 bits (463), Expect = 1e-47
 Identities = 127/423 (30%), Positives = 214/423 (50%), Gaps = 24/423 (5%)

Query: 63  EVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKICKHIPYKKELMQYDMKLIFIL 122
           +V +E++KCLCN+  +S +A+ +    R+   L  R+ + +   +  ++  +D++L+F+L
Sbjct: 112 DVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLL 171

Query: 123 TALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEASVSANSEDAPKYYFTDEDRVI 182
           TAL  ++R +   E   + ++    E+ +  + P  +       S++  +          
Sbjct: 172 TALRTDVRQQLFQELKGVRLLTDTLEL-TLGVTPEGNPPPTLLPSQETER---------- 220

Query: 183 VCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIMTVQTSSKSNDLDLMNNIVNL 242
             E+ K LFN I L +      E++   + +L ++L   + + T+    + +   + VNL
Sbjct: 221 AMEILKVLFN-ITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTE-EFHGHAVNL 278

Query: 243 LTSI--HTLFYMSLTEEIGDKQKPDHIYEGRDMTSLVILLQFLKHQLTASDERQNLYEKL 300
           L ++    L  +   E  GD  +    + G +M  +  LL FL+ +L    +   L E +
Sbjct: 279 LGNLPLKCLDVLLTLEPHGDSTE----FMGVNMDVIRALLIFLEKRL---HKTHRLKESV 331

Query: 301 SPILTVLNKCARV-RVQRKFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDL 359
           +P+L+VL +CAR+ R  RKFL+  VLP LRDV   PE G+ LRN L RL+T   T V+ +
Sbjct: 332 APVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRV 391

Query: 360 VAEFLFVLCKEKVSRMVKYTGFGNXXXXXXXXXXXXXXX-XXXYXXXXXXXXXXYRRHAH 418
            AEFLFVLC E V R +KYTG+GN                   Y          Y+    
Sbjct: 392 AAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKA 451

Query: 419 ALDPVVGCTRPPPADPFRGMTDEQKEYEAMKLVNLFDKMVTAGVVKPARVGADGQLQAVE 478
           +++PV G     P +P  GMT+EQKE+EAMKLV +FDK+    V++P  +   G L +++
Sbjct: 452 SINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQ 511

Query: 479 HVL 481
             +
Sbjct: 512 DAM 514


>AK027461-1|BAB55126.1|  421|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14555 fis, clone NT2RM2001855. ).
          Length = 421

 Score =  190 bits (463), Expect = 1e-47
 Identities = 127/423 (30%), Positives = 214/423 (50%), Gaps = 24/423 (5%)

Query: 63  EVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKICKHIPYKKELMQYDMKLIFIL 122
           +V +E++KCLCN+  +S +A+ +    R+   L  R+ + +   +  ++  +D++L+F+L
Sbjct: 2   DVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLL 61

Query: 123 TALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEASVSANSEDAPKYYFTDEDRVI 182
           TAL  ++R +   E   + ++    E+ +  + P  +       S++  +          
Sbjct: 62  TALRTDVRQQLFQELKGVRLLTDTLEL-TLGVTPEGNPPPTLLPSQETER---------- 110

Query: 183 VCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIMTVQTSSKSNDLDLMNNIVNL 242
             E+ K LFN I L +      E++   + +L ++L   + + T+    + +   + VNL
Sbjct: 111 AMEILKVLFN-ITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTE-EFHGHAVNL 168

Query: 243 LTSI--HTLFYMSLTEEIGDKQKPDHIYEGRDMTSLVILLQFLKHQLTASDERQNLYEKL 300
           L ++    L  +   E  GD  +    + G +M  +  LL FL+ +L    +   L E +
Sbjct: 169 LGNLPLKCLDVLLTLEPHGDSTE----FMGVNMDVIRALLIFLEKRL---HKTHRLKESV 221

Query: 301 SPILTVLNKCARV-RVQRKFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDL 359
           +P+L+VL +CAR+ R  RKFL+  VLP LRDV   PE G+ LRN L RL+T   T V+ +
Sbjct: 222 APVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRV 281

Query: 360 VAEFLFVLCKEKVSRMVKYTGFGNXXXXXXXXXXXXXXX-XXXYXXXXXXXXXXYRRHAH 418
            AEFLFVLC E V R +KYTG+GN                   Y          Y+    
Sbjct: 282 AAEFLFVLCSESVPRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKA 341

Query: 419 ALDPVVGCTRPPPADPFRGMTDEQKEYEAMKLVNLFDKMVTAGVVKPARVGADGQLQAVE 478
           +++PV G     P +P  GMT+EQKE+EAMKLV +FDK+    V++P  +   G L +++
Sbjct: 342 SINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQ 401

Query: 479 HVL 481
             +
Sbjct: 402 DAM 404


>BX538115-1|CAD98025.1|  525|Homo sapiens hypothetical protein
           protein.
          Length = 525

 Score =  190 bits (462), Expect = 1e-47
 Identities = 127/423 (30%), Positives = 214/423 (50%), Gaps = 24/423 (5%)

Query: 63  EVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKICKHIPYKKELMQYDMKLIFIL 122
           +V +E++KCLCN+  +S +A+ +    R+   L  R+ + +   +  ++  +D++L+F+L
Sbjct: 106 DVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLL 165

Query: 123 TALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEASVSANSEDAPKYYFTDEDRVI 182
           TAL  ++R +   E   + ++    E+ +  + P  +       S++  +          
Sbjct: 166 TALRTDVRQQLFQELKGVRLLTDTLEL-TLGVTPEGNPPPTLLPSQETER---------- 214

Query: 183 VCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIMTVQTSSKSNDLDLMNNIVNL 242
             E+ K LFN I L +      E++   + +L ++L   + + T+    + +   + VNL
Sbjct: 215 AMEILKVLFN-ITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTE-EFHGHAVNL 272

Query: 243 LTSI--HTLFYMSLTEEIGDKQKPDHIYEGRDMTSLVILLQFLKHQLTASDERQNLYEKL 300
           L ++    L  +   E  GD  +    + G +M  +  LL FL+ +L    +   L E +
Sbjct: 273 LGNLPLKCLDVLLTLEPHGDSTE----FMGVNMDVIRALLIFLEKRL---HKTHRLKESV 325

Query: 301 SPILTVLNKCARV-RVQRKFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDL 359
           +P+L+VL +CAR+ R  RKFL+  VLP LRDV   PE G+ LRN L RL+T   T V+ +
Sbjct: 326 APVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRV 385

Query: 360 VAEFLFVLCKEKVSRMVKYTGFGNXXXXXXXXXXXXXXX-XXXYXXXXXXXXXXYRRHAH 418
            AEFLFVLC E V R +KYTG+GN                   Y          Y+    
Sbjct: 386 AAEFLFVLCSESVLRFIKYTGYGNAAGLLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKA 445

Query: 419 ALDPVVGCTRPPPADPFRGMTDEQKEYEAMKLVNLFDKMVTAGVVKPARVGADGQLQAVE 478
           +++PV G     P +P  GMT+EQKE+EAMKLV +FDK+    V++P  +   G L +++
Sbjct: 446 SINPVTGRVEEKPPNPMEGMTEEQKEHEAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQ 505

Query: 479 HVL 481
             +
Sbjct: 506 DAM 508


>BC034220-1|AAH34220.1|  496|Homo sapiens RIC8B protein protein.
          Length = 496

 Score =  189 bits (460), Expect = 2e-47
 Identities = 136/448 (30%), Positives = 222/448 (49%), Gaps = 36/448 (8%)

Query: 43  LLEPMESAEKDPTLLVVPCKEVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKIC 102
           LL   +  E D +L  V    V +E++KCLCNI FNS++A+ + +   +A  L   ++ C
Sbjct: 52  LLRLAKLNELDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKC 111

Query: 103 KHIPYKKELMQYDMKLIFILTALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEAS 162
           K   +  ++  +D++L+F+L+ L  +IR + R+E   +  +  L +I   +      +  
Sbjct: 112 KDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYE---LQGLPLLTQILESAFSIKWTDEY 168

Query: 163 VSANSEDAPKYYFTDEDRVIVCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIM 222
            SA   + P     + D  I  E  KALFN+ +  +      E +  QF  + +VL   +
Sbjct: 169 ESAIDHNGPPLSPQETDCAI--EALKALFNVTV--DSWKVHKESDSHQFRVMAAVLRHCL 224

Query: 223 TVQTSSKSNDLDLMNNIVNLLTSIHT----LFYMSLT-EEIGDK-----QKPDH------ 266
            +   ++    +L +N VNLL+++      +    LT EE   +     + P +      
Sbjct: 225 LIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHEETAQEATTLDELPSNKTAEKE 284

Query: 267 --------IYEGRDMTSLVILLQFLKHQLTASDERQNLYEKLSPILTVLNKCARV-RVQR 317
                   +Y G +M ++ +LL F++ ++   D+  +  E L+P+L++L +C+R  R  R
Sbjct: 285 TVLKNNTMVYNGMNMEAIHVLLNFMEKRI---DKGSSYREGLTPVLSLLTECSRAHRNIR 341

Query: 318 KFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDLVAEFLFVLCKEKVSRMVK 377
           KFL+  VLP LRDV+  PE G  +RN L RL+T     V+ + AEFLFVLCKE+V  ++K
Sbjct: 342 KFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLK 401

Query: 378 YTGFGNXXXXXXXXXXXXXXXXXX-YXXXXXXXXXXYRRHAHALDPVVGCTRPPPADPFR 436
           YTG+GN                   Y          Y+     ++ + G    P  +P  
Sbjct: 402 YTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPNINLITGHLEEPMPNPID 461

Query: 437 GMTDEQKEYEAMKLVNLFDKMVTAGVVK 464
            MT+EQKEYEAMKLVN+ DK+     VK
Sbjct: 462 EMTEEQKEYEAMKLVNMLDKLSRRADVK 489


>AK001482-1|BAA91717.1|  536|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10620 fis, clone NT2RP2005495. ).
          Length = 536

 Score =  189 bits (460), Expect = 2e-47
 Identities = 136/448 (30%), Positives = 222/448 (49%), Gaps = 36/448 (8%)

Query: 43  LLEPMESAEKDPTLLVVPCKEVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKIC 102
           LL   +  E D +L  V    V +E++KCLCNI FNS++A+ + +   +A  L   ++ C
Sbjct: 92  LLRLAKLNELDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKC 151

Query: 103 KHIPYKKELMQYDMKLIFILTALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEAS 162
           K   +  ++  +D++L+F+L+ L  +IR + R+E   +  +  L +I   +      +  
Sbjct: 152 KDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYE---LQGLPLLTQILESAFSIKWTDEY 208

Query: 163 VSANSEDAPKYYFTDEDRVIVCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIM 222
            SA   + P     + D  I  E  KALFN+ +  +      E +  QF  + +VL   +
Sbjct: 209 ESAIDHNGPPLSPQETDCAI--EALKALFNVTV--DSWKVHKESDSHQFRVMAAVLRHCL 264

Query: 223 TVQTSSKSNDLDLMNNIVNLLTSIHT----LFYMSLT-EEIGDK-----QKPDH------ 266
            +   ++    +L +N VNLL+++      +    LT EE   +     + P +      
Sbjct: 265 LIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHEETAQEATTLDELPSNKTAEKE 324

Query: 267 --------IYEGRDMTSLVILLQFLKHQLTASDERQNLYEKLSPILTVLNKCARV-RVQR 317
                   +Y G +M ++ +LL F++ ++   D+  +  E L+P+L++L +C+R  R  R
Sbjct: 325 TVLKNNTMVYNGMNMEAIHVLLNFMEKRI---DKGSSYREGLTPVLSLLTECSRAHRNIR 381

Query: 318 KFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDLVAEFLFVLCKEKVSRMVK 377
           KFL+  VLP LRDV+  PE G  +RN L RL+T     V+ + AEFLFVLCKE+V  ++K
Sbjct: 382 KFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLK 441

Query: 378 YTGFGNXXXXXXXXXXXXXXXXXX-YXXXXXXXXXXYRRHAHALDPVVGCTRPPPADPFR 436
           YTG+GN                   Y          Y+     ++ + G    P  +P  
Sbjct: 442 YTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPNINLITGHLEEPMPNPID 501

Query: 437 GMTDEQKEYEAMKLVNLFDKMVTAGVVK 464
            MT+EQKEYEAMKLVN+ DK+     VK
Sbjct: 502 EMTEEQKEYEAMKLVNMLDKLSRRADVK 529


>AY221116-1|AAO65923.1|  513|Homo sapiens brain synembryn protein.
          Length = 513

 Score =  188 bits (457), Expect = 5e-47
 Identities = 134/441 (30%), Positives = 220/441 (49%), Gaps = 36/441 (8%)

Query: 43  LLEPMESAEKDPTLLVVPCKEVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKIC 102
           LL   +  E D +L  V    V +E++KCLCNI FNS++A+ + +   +A  L   ++ C
Sbjct: 70  LLRLAKLNELDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKC 129

Query: 103 KHIPYKKELMQYDMKLIFILTALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEAS 162
           K   +  ++  +D++L+F+L+ L  +IR + R+E   +  +  L +I   +      +  
Sbjct: 130 KDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYE---LQGLPLLTQILESAFTIKWTDEY 186

Query: 163 VSANSEDAPKYYFTDEDRVIVCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIM 222
            SA   + P     + D  I  E  KALFN+ +  +      E +  QF  + +VL   +
Sbjct: 187 ESAIDHNGPPLSPQETDCAI--EALKALFNVTV--DSWKVHKESDSHQFRVMAAVLRHCL 242

Query: 223 TVQTSSKSNDLDLMNNIVNLLTSIHT----LFYMSLT-EEIGDK-----QKPDH------ 266
            +   ++    +L +N VNLL+++      +    LT EE   +     + P +      
Sbjct: 243 LIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHEETAQEATTLDELPSNKTAEKE 302

Query: 267 --------IYEGRDMTSLVILLQFLKHQLTASDERQNLYEKLSPILTVLNKCARV-RVQR 317
                   +Y G +M ++ +LL F++ ++   D+  +  E L+P+L++L +C+R  R  R
Sbjct: 303 TVLKNNTMVYNGMNMEAIHVLLNFMEKRI---DKGSSYREGLTPVLSLLTECSRAHRNIR 359

Query: 318 KFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDLVAEFLFVLCKEKVSRMVK 377
           KFL+  VLP LRDV+  PE G  +RN L RL+T     V+ + AEFLFVLCKE+V  ++K
Sbjct: 360 KFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLK 419

Query: 378 YTGFGNXXXXXXXXXXXXXXXXXX-YXXXXXXXXXXYRRHAHALDPVVGCTRPPPADPFR 436
           YTG+GN                   Y          Y+     ++ + G    P  +P  
Sbjct: 420 YTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPNINLITGHLEEPMPNPID 479

Query: 437 GMTDEQKEYEAMKLVNLFDKM 457
            MT+EQKEYEAMKLVN+ DK+
Sbjct: 480 EMTEEQKEYEAMKLVNMLDKL 500


>BC132689-1|AAI32690.1|  520|Homo sapiens resistance to inhibitors
           of cholinesterase 8 homolog B (C. elegans) protein.
          Length = 520

 Score =  157 bits (381), Expect = 8e-38
 Identities = 113/366 (30%), Positives = 191/366 (52%), Gaps = 35/366 (9%)

Query: 43  LLEPMESAEKDPTLLVVPCKEVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKIC 102
           LL   +  E D +L  V    V +E++KCLCNI FNS++A+ + +   +A  L   ++ C
Sbjct: 92  LLRLAKLNELDDSLEKVSEFPVIVESLKCLCNIVFNSQMAQQLSLELNLAAKLCNLLRKC 151

Query: 103 KHIPYKKELMQYDMKLIFILTALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEAS 162
           K   +  ++  +D++L+F+L+ L  +IR + R+E   +  +  L +I   +      +  
Sbjct: 152 KDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYE---LQGLPLLTQILESAFSIKWTDEY 208

Query: 163 VSANSEDAPKYYFTDEDRVIVCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIM 222
            SA   + P     + D  I  E  KALFN+ +  +      E +  QF  + +VL   +
Sbjct: 209 ESAIDHNGPPLSPQETDCAI--EALKALFNVTV--DSWKVHKESDSHQFRVMAAVLRHCL 264

Query: 223 TVQTSSKSNDLDLMNNIVNLLTSIHT----LFYMSLT-EEIGDK-----QKPDH------ 266
            +   ++    +L +N VNLL+++      +    LT EE   +     + P +      
Sbjct: 265 LIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHEETAQEATTLDELPSNKTAEKE 324

Query: 267 --------IYEGRDMTSLVILLQFLKHQLTASDERQNLYEKLSPILTVLNKCARV-RVQR 317
                   +Y G +M ++ +LL F++ ++   D+  +  E L+P+L++L +C+R  R  R
Sbjct: 325 TVLKNNTMVYNGMNMEAIHVLLNFMEKRI---DKGSSYREGLTPVLSLLTECSRAHRNIR 381

Query: 318 KFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDLVAEFLFVLCKEKVSRMVK 377
           KFL+  VLP LRDV+  PE G  +RN L RL+T     V+ + AEFLFVLCKE+V  ++K
Sbjct: 382 KFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLK 441

Query: 378 YTGFGN 383
           YTG+GN
Sbjct: 442 YTGYGN 447


>AK027090-1|BAB15653.1|  272|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ23437 fis, clone HRC13266. ).
          Length = 272

 Score =  149 bits (362), Expect = 2e-35
 Identities = 84/216 (38%), Positives = 119/216 (55%), Gaps = 5/216 (2%)

Query: 268 YEGRDMTSLVILLQFLKHQLTASDERQNLYEKLSPILTVLNKCARV-RVQRKFLRKAVLP 326
           + G +M  +  LL FL+ +L    +   L E ++P+L+VL +CAR+ R  RKFL+  VLP
Sbjct: 43  FMGVNMDVIRALLIFLEKRL---HKTHRLKESVAPVLSVLTECARMHRPARKFLKAQVLP 99

Query: 327 HLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDLVAEFLFVLCKEKVSRMVKYTGFGNXXX 386
            LRDV   PE G+ LRN L RL+T   T V+ + AEFLFVLC E V R +KYTG+GN   
Sbjct: 100 PLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAG 159

Query: 387 XXXXXXXXXXXX-XXXYXXXXXXXXXXYRRHAHALDPVVGCTRPPPADPFRGMTDEQKEY 445
                           Y          Y+    +++PV G     P +P  GMT+EQKE+
Sbjct: 160 LLAARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEH 219

Query: 446 EAMKLVNLFDKMVTAGVVKPARVGADGQLQAVEHVL 481
           EAMKLV +FDK+    V++P  +   G L +++  +
Sbjct: 220 EAMKLVTMFDKLSRNRVIQPMGMSPRGHLTSLQDAM 255


>AK022870-1|BAB14282.1|  291|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12808 fis, clone NT2RP2002373. ).
          Length = 291

 Score =  113 bits (271), Expect = 2e-24
 Identities = 87/305 (28%), Positives = 156/305 (51%), Gaps = 23/305 (7%)

Query: 63  EVAIEAMKCLCNITFNSELARNVCVNTRIAHGLITRMKICKHIPYKKELMQYDMKLIFIL 122
           +V +E++KCLCN+  +S +A+ +    R+   L  R+ + +   +  ++  +D++L+F+L
Sbjct: 2   DVVLESLKCLCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLL 61

Query: 123 TALIENIRLKFRHEDGAMHMINYLNEIYSESLQPSSDEASVSANSEDAPKYYFTDEDRVI 182
           TAL  ++R +   E   + ++    E+ +  + P  +       S++  +          
Sbjct: 62  TALRTDVRQQLFQELKGVRLLTDTLEL-TLGVTPEGNPPPTLLPSQETER---------- 110

Query: 183 VCELSKALFNLIILPNEDTPTTEKEKQQFTNLVSVLGKIMTVQTSSKSNDLDLMNNIVNL 242
             E+ K LFN I L +      E++   + +L ++L   + + T+    + +   + VNL
Sbjct: 111 AMEILKVLFN-ITLDSIKGEVDEEDAALYRHLGTLLRHCVMIATAGDRTE-EFHGHAVNL 168

Query: 243 LTSI--HTLFYMSLTEEIGDKQKPDHIYEGRDMTSLVILLQFLKHQLTASDERQNLYEKL 300
           L ++    L  +   E  GD  +    + G +M  +  LL FL+ +L    +   L E +
Sbjct: 169 LGNLPLKCLDVLLTLEPHGDSTE----FMGVNMDVIRALLIFLEKRL---HKTHRLKESV 221

Query: 301 SPILTVLNKCARV-RVQRKFLRKAVLPHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDL 359
           +P+L+VL +CAR+ R  RKFL+  VLP LRDV   PE G+ LRN L RL+T   T V+ +
Sbjct: 222 APVLSVLTECARMHRPARKFLKAQVLPPLRDVRTRPEVGEMLRNKLVRLMTHLDTDVKRV 281

Query: 360 VAEFL 364
            AEFL
Sbjct: 282 AAEFL 286


>AK128102-1|BAC87276.1|  258|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46223 fis, clone TESTI4013962. ).
          Length = 258

 Score =  107 bits (256), Expect = 1e-22
 Identities = 53/118 (44%), Positives = 80/118 (67%), Gaps = 4/118 (3%)

Query: 267 IYEGRDMTSLVILLQFLKHQLTASDERQNLYEKLSPILTVLNKCARV-RVQRKFLRKAVL 325
           +Y G +M ++ +LL F++ ++   D+  +  E L+P+L++L +C+R  R  RKFL+  VL
Sbjct: 93  VYNGMNMEAIHVLLNFMEKRI---DKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVL 149

Query: 326 PHLRDVSKPPEQGDELRNHLCRLLTTPVTSVRDLVAEFLFVLCKEKVSRMVKYTGFGN 383
           P LRDV+  PE G  +RN L RL+T     V+ + AEFLFVLCKE+V  ++KYTG+GN
Sbjct: 150 PPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGN 207


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.322    0.136    0.396 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 66,955,318
Number of Sequences: 224733
Number of extensions: 2615149
Number of successful extensions: 8425
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 8352
Number of HSP's gapped (non-prelim): 27
length of query: 493
length of database: 73,234,838
effective HSP length: 93
effective length of query: 400
effective length of database: 52,334,669
effective search space: 20933867600
effective search space used: 20933867600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 67 (31.1 bits)

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