Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001241-TA|BGIBMGA001241-PA|IPR001404|Heat shock protein
Hsp90, IPR003594|ATP-binding region, ATPase-like,
IPR009079|Four-helical cytokine
(658 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC018950-1|AAH18950.1| 704|Homo sapiens TNF receptor-associated... 733 0.0
BC023585-1|AAH23585.1| 704|Homo sapiens TNF receptor-associated... 732 0.0
BC001455-1|AAH01455.2| 699|Homo sapiens TRAP1 protein protein. 732 0.0
AF154108-1|AAF15314.1| 704|Homo sapiens tumor necrosis factor t... 732 0.0
AK223076-1|BAD96796.1| 704|Homo sapiens TNF receptor-associated... 731 0.0
AK223049-1|BAD96769.1| 704|Homo sapiens TNF receptor-associated... 731 0.0
AB209805-1|BAD93042.1| 703|Homo sapiens TNF receptor-associated... 731 0.0
AK223205-1|BAD96925.1| 704|Homo sapiens TNF receptor-associated... 731 0.0
AF043254-1|AAC02679.1| 649|Homo sapiens heat shock protein 75 p... 716 0.0
U12595-1|AAA87704.1| 661|Homo sapiens tumor necrosis factor typ... 683 0.0
AC005203-2|AAC24722.1| 616|Homo sapiens TRAP1 protein. 672 0.0
AK093344-1|BAC04139.1| 579|Homo sapiens protein ( Homo sapiens ... 612 e-174
AJ890085-1|CAI64498.1| 495|Homo sapiens TNF receptor-associated... 567 e-161
AL136543-1|CAB66478.1| 737|Homo sapiens hypothetical protein pr... 235 4e-61
M16660-1|AAA36025.1| 724|Homo sapiens protein ( Human 90-kDa he... 235 5e-61
J04988-1|AAA36026.1| 724|Homo sapiens protein ( Human 90 kD hea... 235 5e-61
DQ314872-1|ABC40731.1| 724|Homo sapiens heat shock 90kDa protei... 235 5e-61
BC068474-1|AAH68474.1| 724|Homo sapiens heat shock protein 90kD... 235 5e-61
BC016753-1|AAH16753.1| 724|Homo sapiens heat shock protein 90kD... 235 5e-61
BC014485-1|AAH14485.1| 724|Homo sapiens heat shock protein 90kD... 235 5e-61
BC012807-1|AAH12807.1| 724|Homo sapiens heat shock protein 90kD... 235 5e-61
BC009206-1|AAH09206.2| 650|Homo sapiens HSP90AB1 protein protein. 235 5e-61
BC004928-1|AAH04928.1| 724|Homo sapiens heat shock protein 90kD... 235 5e-61
AY359878-1|AAQ63401.1| 724|Homo sapiens heat shock 90kDa protei... 235 5e-61
AL139392-3|CAI20095.1| 724|Homo sapiens heat shock protein 90kD... 235 5e-61
AF275719-1|AAF82792.1| 632|Homo sapiens chaperone protein HSP90... 235 5e-61
X15183-1|CAA33259.1| 732|Homo sapiens protein ( Human mRNA for ... 221 5e-57
M27024-1|AAA63194.1| 732|Homo sapiens heat shock protein protein. 221 5e-57
DQ314871-1|ABC40730.1| 854|Homo sapiens heat shock 90kDa protei... 221 5e-57
BC121062-1|AAI21063.1| 732|Homo sapiens heat shock protein 90kD... 221 5e-57
BC023006-1|AAH23006.2| 638|Homo sapiens HSP90AA1 protein protein. 221 5e-57
BC000987-1|AAH00987.1| 548|Homo sapiens HSP90AA1 protein protein. 221 5e-57
AJ890083-1|CAI64496.1| 732|Homo sapiens Heat shock protein HSP ... 221 5e-57
AJ890082-1|CAI64495.1| 854|Homo sapiens Heat shock protein HSP ... 221 5e-57
AF028832-1|AAC25497.1| 539|Homo sapiens Hsp89-alpha-delta-N pro... 221 5e-57
X15187-1|CAA33261.1| 803|Homo sapiens precursor polypeptide (AA... 205 4e-52
BC066656-1|AAH66656.1| 803|Homo sapiens heat shock protein 90kD... 205 4e-52
AY040226-1|AAK74072.1| 782|Homo sapiens heat shock protein gp96... 205 4e-52
AJ890084-1|CAI64497.1| 802|Homo sapiens tumor rejection antigen... 205 4e-52
BC007989-1|AAH07989.2| 422|Homo sapiens HSP90AA1 protein protein. 198 7e-50
BC108695-1|AAI08696.1| 585|Homo sapiens HSP90AA1 protein protein. 195 5e-49
X07270-1|CAA30255.1| 312|Homo sapiens protein ( Human mRNA for ... 184 1e-45
M30626-1|AAA36023.1| 312|Homo sapiens heat shock protein 86 pro... 184 1e-45
BC007327-1|AAH07327.1| 351|Homo sapiens HSP90AB1 protein protein. 180 1e-44
AY956764-1|AAX38251.1| 597|Homo sapiens heat shock protein 90Bc... 180 1e-44
BC009195-1|AAH09195.1| 315|Homo sapiens HSP90B1 protein protein. 175 3e-43
AB209534-1|BAD92771.1| 576|Homo sapiens tumor rejection antigen... 175 3e-43
M30627-1|AAA36024.1| 312|Homo sapiens heat shock protein 86 pro... 175 4e-43
AK025370-1|BAB15121.1| 362|Homo sapiens protein ( Homo sapiens ... 173 2e-42
AY956769-1|AAX38256.1| 453|Homo sapiens heat shock protein 94c ... 146 2e-34
AY956765-1|AAX38252.1| 505|Homo sapiens heat shock protein 90Bd... 139 3e-32
AY956763-1|AAX38250.1| 422|Homo sapiens heat shock protein 90Bb... 112 4e-24
AY956768-1|AAX38255.1| 399|Homo sapiens heat shock protein 94b ... 103 2e-21
D17804-1|BAA22050.1| 130|Homo sapiens heat shock protein beta p... 99 6e-20
AL139392-5|CAI20097.1| 149|Homo sapiens heat shock protein 90kD... 98 8e-20
AL139392-4|CAI20096.1| 141|Homo sapiens heat shock protein 90kD... 95 5e-19
AL139392-6|CAI20098.1| 170|Homo sapiens heat shock protein 90kD... 91 9e-18
AY956760-1|AAX38247.1| 418|Homo sapiens heat shock protein 90Ad... 87 1e-16
AL139392-2|CAI20094.1| 168|Homo sapiens heat shock protein 90kD... 86 4e-16
S70561-1|AAD14062.1| 68|Homo sapiens 90-kda heat shock protein... 61 1e-08
AY956767-1|AAX38254.1| 361|Homo sapiens heat shock protein 90Bf... 56 4e-07
AY956761-1|AAX38248.1| 334|Homo sapiens heat shock protein 90Ae... 55 9e-07
BC029541-1|AAH29541.2| 277|Homo sapiens LETM2 protein protein. 36 0.60
AY173945-1|AAO49715.1| 444|Homo sapiens leucine zipper-EF-hand ... 36 0.60
AK058138-1|BAB71680.1| 396|Homo sapiens protein ( Homo sapiens ... 36 0.60
BC019324-1|AAH19324.1| 525|Homo sapiens alanyl-tRNA synthetase ... 33 2.4
BC004172-1|AAH04172.1| 525|Homo sapiens alanyl-tRNA synthetase ... 33 2.4
D87666-2|BAA13431.1| 151|Homo sapiens heat shock protein 90 pro... 33 4.2
AK127078-1|BAC86815.1| 844|Homo sapiens protein ( Homo sapiens ... 32 5.6
AL137254-1|CAB70656.1| 196|Homo sapiens hypothetical protein pr... 31 9.8
AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4 ... 31 9.8
AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4b... 31 9.8
>BC018950-1|AAH18950.1| 704|Homo sapiens TNF receptor-associated
protein 1 protein.
Length = 704
Score = 733 bits (1811), Expect = 0.0
Identities = 349/636 (54%), Positives = 485/636 (76%), Gaps = 11/636 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 77 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 133
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 134 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 189
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 190 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 248
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 249 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVRE 308
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 309 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 368
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 369 KVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 428
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS L +GQ TSLS+Y+S
Sbjct: 429 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYAS 488
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 489 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 548
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 549 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 608
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMV 622
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL++L +++ LA ++
Sbjct: 609 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLL 668
Query: 623 AQQLFSNAMVTAGLVMDPRNLITHINDLLVKVLEKH 658
Q++ NAM+ AGLV DPR ++ +N+LLVK LE+H
Sbjct: 669 VDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 704
>BC023585-1|AAH23585.1| 704|Homo sapiens TNF receptor-associated
protein 1 protein.
Length = 704
Score = 732 bits (1810), Expect = 0.0
Identities = 349/636 (54%), Positives = 485/636 (76%), Gaps = 11/636 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 77 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 133
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 134 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 189
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 190 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 248
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 249 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVGE 308
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 309 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 368
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 369 KVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 428
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS L +GQ TSLS+Y+S
Sbjct: 429 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYAS 488
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 489 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 548
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 549 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 608
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMV 622
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL++L +++ LA ++
Sbjct: 609 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLL 668
Query: 623 AQQLFSNAMVTAGLVMDPRNLITHINDLLVKVLEKH 658
Q++ NAM+ AGLV DPR ++ +N+LLVK LE+H
Sbjct: 669 VDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 704
>BC001455-1|AAH01455.2| 699|Homo sapiens TRAP1 protein protein.
Length = 699
Score = 732 bits (1810), Expect = 0.0
Identities = 349/636 (54%), Positives = 485/636 (76%), Gaps = 11/636 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 72 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 128
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 129 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 184
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 185 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 243
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 244 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVGE 303
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 304 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 363
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 364 KVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 423
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS L +GQ TSLS+Y+S
Sbjct: 424 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYAS 483
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 484 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 543
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 544 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 603
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMV 622
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL++L +++ LA ++
Sbjct: 604 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLCASEPGLAQLL 663
Query: 623 AQQLFSNAMVTAGLVMDPRNLITHINDLLVKVLEKH 658
Q++ NAM+ AGLV DPR ++ +N+LLVK LE+H
Sbjct: 664 VDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 699
>AF154108-1|AAF15314.1| 704|Homo sapiens tumor necrosis factor type
1 receptor associated protein protein.
Length = 704
Score = 732 bits (1810), Expect = 0.0
Identities = 349/636 (54%), Positives = 485/636 (76%), Gaps = 11/636 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 77 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 133
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 134 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 189
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 190 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 248
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 249 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVGE 308
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 309 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 368
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 369 KVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 428
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS L +GQ TSLS+Y+S
Sbjct: 429 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYAS 488
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 489 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 548
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 549 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 608
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMV 622
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL++L +++ LA ++
Sbjct: 609 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLL 668
Query: 623 AQQLFSNAMVTAGLVMDPRNLITHINDLLVKVLEKH 658
Q++ NAM+ AGLV DPR ++ +N+LLVK LE+H
Sbjct: 669 VDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 704
>AK223076-1|BAD96796.1| 704|Homo sapiens TNF receptor-associated
protein 1 variant protein.
Length = 704
Score = 731 bits (1807), Expect = 0.0
Identities = 348/636 (54%), Positives = 485/636 (76%), Gaps = 11/636 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 77 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 133
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 134 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 189
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 190 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 248
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 249 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVGE 308
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 309 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 368
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 369 KVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 428
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IA+LLR+ESS L +GQ TSLS+Y+S
Sbjct: 429 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIARLLRYESSALPSGQLTSLSEYAS 488
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 489 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 548
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 549 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 608
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMV 622
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL++L +++ LA ++
Sbjct: 609 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLL 668
Query: 623 AQQLFSNAMVTAGLVMDPRNLITHINDLLVKVLEKH 658
Q++ NAM+ AGLV DPR ++ +N+LLVK LE+H
Sbjct: 669 VDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 704
>AK223049-1|BAD96769.1| 704|Homo sapiens TNF receptor-associated
protein 1 variant protein.
Length = 704
Score = 731 bits (1807), Expect = 0.0
Identities = 348/636 (54%), Positives = 485/636 (76%), Gaps = 11/636 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 77 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 133
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 134 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 189
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 190 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 248
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 249 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVGE 308
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 309 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 368
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 369 KVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 428
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IA+LLR+ESS L +GQ TSLS+Y+S
Sbjct: 429 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIARLLRYESSALPSGQLTSLSEYAS 488
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 489 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 548
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 549 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 608
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMV 622
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL++L +++ LA ++
Sbjct: 609 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLL 668
Query: 623 AQQLFSNAMVTAGLVMDPRNLITHINDLLVKVLEKH 658
Q++ NAM+ AGLV DPR ++ +N+LLVK LE+H
Sbjct: 669 VDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 704
>AB209805-1|BAD93042.1| 703|Homo sapiens TNF receptor-associated
protein 1 variant protein.
Length = 703
Score = 731 bits (1807), Expect = 0.0
Identities = 348/636 (54%), Positives = 485/636 (76%), Gaps = 11/636 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 76 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 132
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 133 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 188
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 189 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 247
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 248 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVRE 307
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 308 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 367
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSE+IPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 368 KVLIQTKATDILPKWLRFIRGVVDSEEIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 427
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS L +GQ TSLS+Y+S
Sbjct: 428 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYAS 487
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 488 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 547
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 548 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 607
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMV 622
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL++L +++ LA ++
Sbjct: 608 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLL 667
Query: 623 AQQLFSNAMVTAGLVMDPRNLITHINDLLVKVLEKH 658
Q++ NAM+ AGLV DPR ++ +N+LLVK LE+H
Sbjct: 668 VDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 703
>AK223205-1|BAD96925.1| 704|Homo sapiens TNF receptor-associated
protein 1 variant protein.
Length = 704
Score = 731 bits (1806), Expect = 0.0
Identities = 348/636 (54%), Positives = 484/636 (76%), Gaps = 11/636 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 77 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 133
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 134 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 189
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 190 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 248
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 249 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVRE 308
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+I SI YVP+ KP +F++SR+ VALYSR
Sbjct: 309 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIHSIFYVPDMKPSMFDVSRELGSSVALYSR 368
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 369 KVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 428
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS L +GQ TSLS+Y+S
Sbjct: 429 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYAS 488
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 489 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 548
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 549 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 608
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMV 622
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL++L +++ LA ++
Sbjct: 609 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLL 668
Query: 623 AQQLFSNAMVTAGLVMDPRNLITHINDLLVKVLEKH 658
Q++ NAM+ AGLV DPR ++ +N+LLVK LE+H
Sbjct: 669 VDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 704
>AF043254-1|AAC02679.1| 649|Homo sapiens heat shock protein 75
protein.
Length = 649
Score = 716 bits (1771), Expect = 0.0
Identities = 345/636 (54%), Positives = 483/636 (75%), Gaps = 14/636 (2%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 25 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 81
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 82 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 137
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 138 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 196
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 197 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVRE 256
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 257 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 316
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSE+IPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 317 KVLIQTKATDILPKWLRFIRGVVDSEEIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 376
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS ++GQ TSLS+Y++
Sbjct: 377 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESS--ASGQLTSLSEYAA 434
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 435 HWA-GTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 493
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 494 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 553
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMV 622
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL++L +++ LA ++
Sbjct: 554 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLL 613
Query: 623 AQQLFSNAMVTAGLVMDPRNLITHINDLLVKVLEKH 658
Q++ NAM+ AGLV DPR ++ +N+LLVK LE+H
Sbjct: 614 VDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 649
>U12595-1|AAA87704.1| 661|Homo sapiens tumor necrosis factor type 1
receptor associated protein protein.
Length = 661
Score = 683 bits (1687), Expect = 0.0
Identities = 327/587 (55%), Positives = 449/587 (76%), Gaps = 11/587 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 62 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 118
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 119 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 174
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 175 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 233
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 234 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVGE 293
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 294 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 353
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 354 KVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 413
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS L +GQ TSLS+Y+S
Sbjct: 414 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYAS 473
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 474 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 533
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 534 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 593
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLH 609
++ V EM AARHF+R Q T+E R LL+P LEIN +H ++KKL+
Sbjct: 594 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLN 640
>AC005203-2|AAC24722.1| 616|Homo sapiens TRAP1 protein.
Length = 616
Score = 672 bits (1660), Expect = 0.0
Identities = 323/577 (55%), Positives = 441/577 (76%), Gaps = 11/577 (1%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
S+ES++G + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALEK R+ VS
Sbjct: 47 STESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVS--- 103
Query: 86 ESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKK 145
+ L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARSGSK+F++ ++
Sbjct: 104 DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQN 159
Query: 146 QGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVE 205
Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG +EI EA GV
Sbjct: 160 Q-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVR 218
Query: 206 IGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ +
Sbjct: 219 TGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVRE 278
Query: 266 EQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSR 325
QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSR
Sbjct: 279 WQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSR 338
Query: 326 KILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVE 385
K+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR VL R +KF ++
Sbjct: 339 KVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFID 398
Query: 386 MSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSS 445
S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS L +GQ TSLS+Y+S
Sbjct: 399 QSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYAS 458
Query: 446 RQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALV 505
R + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+
Sbjct: 459 RMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLI 518
Query: 506 SVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPC 562
SVE D+ D + + +E L + + +EL+++++ L +V +V+ T +LD+HP
Sbjct: 519 SVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPA 578
Query: 563 VIVVPEMAAARHFIRTQAQNLTEENRFALLRPQLEIN 599
++ V EM AARHF+R Q T+E R LL+P LEIN
Sbjct: 579 MVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEIN 615
>AK093344-1|BAC04139.1| 579|Homo sapiens protein ( Homo sapiens
cDNA FLJ36025 fis, clone TESTI2016701, highly similar to
TUMOR NECROSIS FACTOR TYPE 1 RECEPTOR ASSOCIATED
PROTEIN. ).
Length = 579
Score = 612 bits (1512), Expect = e-174
Identities = 297/529 (56%), Positives = 403/529 (76%), Gaps = 14/529 (2%)
Query: 18 FSTVTEKQSSE---SLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALE 74
FST T + E S+ + K EFQAET+ LLDIVARSLYS+KEVFIRELISNASDALE
Sbjct: 59 FSTQTAEDKEEPLHSIISSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALE 118
Query: 75 KFRYLSVSSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARS 134
K R+ VS + L E+ EI L T+ + TIT QD+GIGMT+EEL NLGTIARS
Sbjct: 119 KLRHKLVS---DGQALPEM----EIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARS 171
Query: 135 GSKSFIEEIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSG 194
GSK+F++ ++ Q AE +S IIGQFGVGFYSAFMVAD++EV++RS+ S GYQW SDGSG
Sbjct: 172 GSKAFLDALQNQ-AEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWPSDGSG 230
Query: 195 TYEIQEADGVEIGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKP 254
+EI EA GV GTKI+++LK+DC+EF+ + V+ ++ KYSNFVS P++LN ++N+++
Sbjct: 231 VFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQA 290
Query: 255 LWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFELSR 314
+W+ +PK++ + QH EFY++++ ++DKPR+TLHYKTDAPL+IRSI YVP+ KP +F++SR
Sbjct: 291 IWMMDPKDVGEWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSR 350
Query: 315 DSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTV 374
+ VALYSRK+LI++KA +ILPKWLRF++GVVDSEDIPLNLSRELLQ SALI KLR V
Sbjct: 351 ELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDV 410
Query: 375 LTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSN 434
L R +KF ++ S+KD +Y F++DY +F++EGIVT+ KE+IAKLLR+ESS L +
Sbjct: 411 LQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPS 470
Query: 435 GQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLL 494
GQ TSLS+Y+SR + ++I+YL AP+R LAE SPYYE++KK+D EVLFC+E +DEL LL
Sbjct: 471 GQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLL 530
Query: 495 ELKEFGGRALVSVENDMQRDPLDK---SESIIGSEGLQQSQVDELISFL 540
L+EF + L+SVE D+ D + + +E L + + +EL++++
Sbjct: 531 HLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWM 579
>AJ890085-1|CAI64498.1| 495|Homo sapiens TNF receptor-associated
protein 1 protein.
Length = 495
Score = 567 bits (1400), Expect = e-161
Identities = 257/495 (51%), Positives = 375/495 (75%), Gaps = 3/495 (0%)
Query: 167 MVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEIGTKIVVYLKTDCREFADDDT 226
MVAD++EV++RS+ S GYQW SDGSG +EI EA GV GTKI+++LK+DC+EF+ +
Sbjct: 1 MVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEAR 60
Query: 227 VKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTL 286
V+ ++ KYSNFVS P++LN ++N+++ +W+ +PK++ + QH EFY++++ ++DKPR+TL
Sbjct: 61 VRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTL 120
Query: 287 HYKTDAPLSIRSILYVPEGKPGLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKG 346
HYKTDAPL+IRSI YVP+ KP +F++SR+ VALYSRK+LI++KA +ILPKWLRF++G
Sbjct: 121 HYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRG 180
Query: 347 VVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLK 406
VVDSE+IPLNLSRELLQ SALI KLR VL R +KF ++ S+KD +Y F++DY +F++
Sbjct: 181 VVDSEEIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMR 240
Query: 407 EGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAE 466
EGIVT+ KE+IAKLLR+ESS L +GQ TSLS+Y+SR + ++I+YL AP+R LAE
Sbjct: 241 EGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAE 300
Query: 467 TSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDK---SESII 523
SPYYE++KK+D EVLFC+E +DEL LL L+EF + L+SVE D+ D + +
Sbjct: 301 HSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSP 360
Query: 524 GSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIRTQAQNL 583
+E L + + +EL+++++ L +V +V+ T +LD+HP ++ V EM AARHF+R Q
Sbjct: 361 AAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAK 420
Query: 584 TEENRFALLRPQLEINAKHPIVKKLHKLMSTDKELATMVAQQLFSNAMVTAGLVMDPRNL 643
T+E R LL+P LEIN +H ++KKL++L +++ LA ++ Q++ NAM+ AGLV DPR +
Sbjct: 421 TQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAM 480
Query: 644 ITHINDLLVKVLEKH 658
+ +N+LLVK LE+H
Sbjct: 481 VGRLNELLVKALERH 495
>AL136543-1|CAB66478.1| 737|Homo sapiens hypothetical protein
protein.
Length = 737
Score = 235 bits (575), Expect = 4e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKAIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>M16660-1|AAA36025.1| 724|Homo sapiens protein ( Human 90-kDa
heat-shock protein gene, cDNA, complete cds. ).
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 178 bits (433), Expect = 6e-44
Identities = 92/208 (44%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADG--VEIGTKIVVYLKT 216
GVGFYSA++VA+K+ V + + D Y W S G++ ++ G + +GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVIRKHN--DDEQYAWESSAGGSFTVRADHGEPIGMGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>J04988-1|AAA36026.1| 724|Homo sapiens protein ( Human 90 kD heat
shock protein gene, complete cds. ).
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>DQ314872-1|ABC40731.1| 724|Homo sapiens heat shock 90kDa protein
1, beta protein.
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>BC068474-1|AAH68474.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>BC016753-1|AAH16753.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>BC014485-1|AAH14485.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>BC012807-1|AAH12807.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>BC009206-1|AAH09206.2| 650|Homo sapiens HSP90AB1 protein protein.
Length = 650
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 184 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 241
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 242 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 300
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 301 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 359
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 360 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 416
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 417 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 476
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 477 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 534
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 535 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 594
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 595 SLEDPQ---THSN 604
Score = 129 bits (312), Expect = 3e-29
Identities = 65/141 (46%), Positives = 97/141 (68%), Gaps = 7/141 (4%)
Query: 106 QNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQFGVGFYSA 165
Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQFGVGFYSA
Sbjct: 6 QERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQFGVGFYSA 62
Query: 166 FMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKTDCREFAD 223
++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK D E+ +
Sbjct: 63 YLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLE 120
Query: 224 DDTVKSIIKKYSNFVSSPIFL 244
+ VK ++KK+S F+ PI L
Sbjct: 121 ERRVKEVVKKHSQFIGYPITL 141
>BC004928-1|AAH04928.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>AY359878-1|AAQ63401.1| 724|Homo sapiens heat shock 90kDa protein 1
beta protein.
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>AL139392-3|CAI20095.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), classae) protein.
Length = 724
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 374
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 375 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 433
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 434 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 490
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 551 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 608
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 609 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 668
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 669 SLEDPQ---THSN 678
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
>AF275719-1|AAF82792.1| 632|Homo sapiens chaperone protein HSP90
beta protein.
Length = 632
Score = 235 bits (574), Expect = 5e-61
Identities = 140/433 (32%), Positives = 236/433 (54%), Gaps = 19/433 (4%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 166 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 223
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWL 341
H+ + L R++L++P P LFE + + + LY R++ I + ++P++L
Sbjct: 224 LAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKN-NIKLYVRRVFIMDSCDELIPEYL 282
Query: 342 RFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDY 401
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +
Sbjct: 283 NFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAF 341
Query: 402 SIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS 461
S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S
Sbjct: 342 SKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGES 398
Query: 462 RELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSES 521
+E S + E ++KR EV++ E DE + +LKEF G++LVSV + P D+ E
Sbjct: 399 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 458
Query: 522 IIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MAAARHFIRT 578
E +++ + L +K L KV V + +L S PC IV A ++
Sbjct: 459 KKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKA 516
Query: 579 QAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFSNAMVTAGL 636
QA + + + LEIN HPIV+ L + DK + + LF A++++G
Sbjct: 517 QALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGF 576
Query: 637 VM-DPRNLITHIN 648
+ DP+ TH N
Sbjct: 577 SLEDPQ---THSN 586
Score = 112 bits (269), Expect = 4e-24
Identities = 57/128 (44%), Positives = 87/128 (67%), Gaps = 7/128 (5%)
Query: 119 MTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRS 178
MTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQFGVGFYSA++VA+K+ V T+
Sbjct: 1 MTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQFGVGFYSAYLVAEKVVVITKH 57
Query: 179 SKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSN 236
+ D Y W S G++ ++ G I GTK++++LK D E+ ++ VK ++KK+S
Sbjct: 58 N--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQ 115
Query: 237 FVSSPIFL 244
F+ PI L
Sbjct: 116 FIGYPITL 123
>X15183-1|CAA33259.1| 732|Homo sapiens protein ( Human mRNA for
90-kDa heat-shock protein. ).
Length = 732
Score = 221 bits (541), Expect = 5e-57
Identities = 129/413 (31%), Positives = 229/413 (55%), Gaps = 17/413 (4%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 284 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 343
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 344 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 402
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 403 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 459
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 460 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 518
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 519 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 576
Query: 542 TNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIR-TQAQNLTEENRFALL--RPQLEI 598
L KV V + +L + PC IV + R +AQ L + + + + LEI
Sbjct: 577 DILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEI 636
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
N H I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 637 NPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 686
Score = 182 bits (444), Expect = 3e-45
Identities = 96/225 (42%), Positives = 148/225 (65%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K RY ++
Sbjct: 5 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYETL 64
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
+ + + KEL I L +KQ+RT+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 65 TDPSKLDSGKEL----HINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 121 ALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 175
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 176 TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 220
>M27024-1|AAA63194.1| 732|Homo sapiens heat shock protein protein.
Length = 732
Score = 221 bits (541), Expect = 5e-57
Identities = 129/413 (31%), Positives = 229/413 (55%), Gaps = 17/413 (4%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 284 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 343
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 344 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 402
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 403 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 459
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 460 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 518
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 519 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 576
Query: 542 TNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIR-TQAQNLTEENRFALL--RPQLEI 598
L KV V + +L + PC IV + R +AQ L + + + + LEI
Sbjct: 577 DILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEI 636
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
N H I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 637 NPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 686
Score = 184 bits (447), Expect = 1e-45
Identities = 97/225 (43%), Positives = 148/225 (65%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K RY S+
Sbjct: 5 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESL 64
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
+ + + KEL I L +KQ+RT+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 65 TDPSKLDSGKEL----HINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 121 ALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 175
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 176 TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 220
>DQ314871-1|ABC40730.1| 854|Homo sapiens heat shock 90kDa protein
1, alpha protein.
Length = 854
Score = 221 bits (541), Expect = 5e-57
Identities = 129/413 (31%), Positives = 229/413 (55%), Gaps = 17/413 (4%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 406 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 465
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 466 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 524
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 525 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 581
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 582 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 640
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 641 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 698
Query: 542 TNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIR-TQAQNLTEENRFALL--RPQLEI 598
L KV V + +L + PC IV + R +AQ L + + + + LEI
Sbjct: 699 DILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEI 758
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
N H I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 759 NPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 808
Score = 184 bits (447), Expect = 1e-45
Identities = 97/225 (43%), Positives = 148/225 (65%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K RY S+
Sbjct: 127 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESL 186
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
+ + + KEL I L +KQ+RT+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 187 TDPSKLDSGKEL----HINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 242
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 243 ALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 297
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 298 TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 342
>BC121062-1|AAI21063.1| 732|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class A member 1 protein.
Length = 732
Score = 221 bits (541), Expect = 5e-57
Identities = 129/413 (31%), Positives = 229/413 (55%), Gaps = 17/413 (4%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 284 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 343
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 344 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 402
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 403 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 459
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 460 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 518
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 519 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 576
Query: 542 TNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIR-TQAQNLTEENRFALL--RPQLEI 598
L KV V + +L + PC IV + R +AQ L + + + + LEI
Sbjct: 577 DILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEI 636
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
N H I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 637 NPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 686
Score = 184 bits (447), Expect = 1e-45
Identities = 97/225 (43%), Positives = 148/225 (65%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K RY S+
Sbjct: 5 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESL 64
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
+ + + KEL I L +KQ+RT+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 65 TDPSKLDSGKEL----HINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 121 ALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 175
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 176 TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 220
>BC023006-1|AAH23006.2| 638|Homo sapiens HSP90AA1 protein protein.
Length = 638
Score = 221 bits (541), Expect = 5e-57
Identities = 129/413 (31%), Positives = 229/413 (55%), Gaps = 17/413 (4%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 190 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 249
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 250 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 308
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 309 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 365
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 366 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 424
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 425 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 482
Query: 542 TNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIR-TQAQNLTEENRFALL--RPQLEI 598
L KV V + +L + PC IV + R +AQ L + + + + LEI
Sbjct: 483 DILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEI 542
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
N H I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 543 NPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 592
Score = 118 bits (283), Expect = 9e-26
Identities = 59/131 (45%), Positives = 90/131 (68%), Gaps = 7/131 (5%)
Query: 116 GIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVF 175
GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQFGVGFYSA++VA+K+ V
Sbjct: 1 GIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVI 57
Query: 176 TRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKTDCREFADDDTVKSIIKK 233
T+ + D Y W S G++ ++ G + GTK++++LK D E+ ++ +K I+KK
Sbjct: 58 TKHN--DDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKK 115
Query: 234 YSNFVSSPIFL 244
+S F+ PI L
Sbjct: 116 HSQFIGYPITL 126
>BC000987-1|AAH00987.1| 548|Homo sapiens HSP90AA1 protein protein.
Length = 548
Score = 221 bits (541), Expect = 5e-57
Identities = 129/413 (31%), Positives = 229/413 (55%), Gaps = 17/413 (4%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 100 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 159
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 160 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 218
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 219 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 275
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 276 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 334
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 335 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 392
Query: 542 TNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIR-TQAQNLTEENRFALL--RPQLEI 598
L KV V + +L + PC IV + R +AQ L + + + + LEI
Sbjct: 393 DILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEI 452
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
N H I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 453 NPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 502
Score = 37.5 bits (83), Expect = 0.15
Identities = 14/36 (38%), Positives = 25/36 (69%)
Query: 209 KIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
K++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 1 KVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 36
>AJ890083-1|CAI64496.1| 732|Homo sapiens Heat shock protein HSP
90-alpha 4 protein.
Length = 732
Score = 221 bits (541), Expect = 5e-57
Identities = 129/413 (31%), Positives = 229/413 (55%), Gaps = 17/413 (4%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 284 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 343
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 344 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 402
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 403 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 459
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 460 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 518
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 519 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 576
Query: 542 TNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIR-TQAQNLTEENRFALL--RPQLEI 598
L KV V + +L + PC IV + R +AQ L + + + + LEI
Sbjct: 577 DILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEI 636
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
N H I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 637 NPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 686
Score = 184 bits (447), Expect = 1e-45
Identities = 97/225 (43%), Positives = 148/225 (65%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K RY S+
Sbjct: 5 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESL 64
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
+ + + KEL I L +KQ+RT+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 65 TDPSKLDSGKEL----HINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 121 ALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 175
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 176 TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 220
>AJ890082-1|CAI64495.1| 854|Homo sapiens Heat shock protein HSP
90-alpha 2 protein.
Length = 854
Score = 221 bits (541), Expect = 5e-57
Identities = 129/413 (31%), Positives = 229/413 (55%), Gaps = 17/413 (4%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 406 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 465
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 466 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 524
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 525 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 581
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 582 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 640
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 641 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 698
Query: 542 TNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIR-TQAQNLTEENRFALL--RPQLEI 598
L KV V + +L + PC IV + R +AQ L + + + + LEI
Sbjct: 699 DILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEI 758
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
N H I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 759 NPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 808
Score = 182 bits (444), Expect = 3e-45
Identities = 97/225 (43%), Positives = 146/225 (64%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K RY
Sbjct: 127 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY--- 183
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
S+ + L + R L I L +KQ RT+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 184 ESLTDPSKL-DSGRELHINLIPNKQGRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 242
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 243 ALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 297
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 298 TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 342
>AF028832-1|AAC25497.1| 539|Homo sapiens Hsp89-alpha-delta-N
protein.
Length = 539
Score = 221 bits (541), Expect = 5e-57
Identities = 129/413 (31%), Positives = 229/413 (55%), Gaps = 17/413 (4%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 91 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 150
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 151 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 209
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 210 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 266
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 267 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 325
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 326 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 383
Query: 542 TNLTGKVFDVRTTQKLDSHPCVIVVPEMAAARHFIR-TQAQNLTEENRFALL--RPQLEI 598
L KV V + +L + PC IV + R +AQ L + + + + LEI
Sbjct: 384 DILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEI 443
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
N H I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 444 NPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 493
>X15187-1|CAA33261.1| 803|Homo sapiens precursor polypeptide (AA-21
to 782) protein.
Length = 803
Score = 205 bits (500), Expect = 4e-52
Identities = 125/402 (31%), Positives = 218/402 (54%), Gaps = 20/402 (4%)
Query: 249 VNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKP- 307
+N IKP+W KE+ ++++ FYK S D P +H+ + ++ +SIL+VP P
Sbjct: 336 MNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPR 395
Query: 308 GLFEL--SRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNS 365
GLF+ S+ SD + LY R++ I +++PK+L FVKGVVDS+D+PLN+SRE LQ
Sbjct: 396 GLFDEYGSKKSDY-IKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 454
Query: 366 ALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLL 425
L+ +R L + L + +++ D + F+K++ +K G++ S + +AKLL
Sbjct: 455 KLLKVIRKKLVRKTLDMIKKIA--DDKYNDTFWKEFGTNIKLGVIEDHS--NRTRLAKLL 510
Query: 426 RFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCY 485
RF+SS TSL Y R K+ Q I+++A SR+ AE+SP+ E L K+ EV++
Sbjct: 511 RFQSSHHPT-DITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLT 569
Query: 486 EMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTN-L 544
E DE + L EF G+ +V + + D+SE S + + + L++++K L
Sbjct: 570 EPVDEYCIQALPEFDGKRFQNVAKEGVK--FDESEKTKESREAVEKEFEPLLNWMKDKAL 627
Query: 545 TGKVFDVRTTQKLDSHPCVIVVPEMAAA---RHFIRTQAQNLTEE---NRFALLRPQLEI 598
K+ +Q+L PC +V + + ++ QA ++ N +A + EI
Sbjct: 628 KDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEI 687
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM 638
N +HP+++ + + + D++ T+ +A LF A + +G ++
Sbjct: 688 NPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLL 729
Score = 175 bits (427), Expect = 3e-43
Identities = 93/245 (37%), Positives = 153/245 (62%), Gaps = 12/245 (4%)
Query: 30 LKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGN 89
L+ KSEK FQAE ++ ++ SLY +KE+F+RELISNASDAL+K R +S++ N
Sbjct: 69 LREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLT----DEN 124
Query: 90 LKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEI--KKQG 147
+ L +++ DK+ + D+G+GMT+EEL +NLGTIA+SG+ F+ ++ ++
Sbjct: 125 ALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQED 184
Query: 148 AEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI- 206
+ S +IGQFGVGFYSAF+VADK+ + T D+ + W SD + I + G +
Sbjct: 185 GQSTSELIGQFGVGFYSAFLVADKV-IVTSKHNNDTQ-HIWESDSNEFSVIADPRGNTLG 242
Query: 207 -GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GT I + LK + ++ + DT+K+++KKYS F++ PI++ + + +++ E +E +
Sbjct: 243 RGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEE--PMEEEEAAK 300
Query: 266 EQHIE 270
E+ E
Sbjct: 301 EEKEE 305
>BC066656-1|AAH66656.1| 803|Homo sapiens heat shock protein 90kDa
beta (Grp94), member 1 protein.
Length = 803
Score = 205 bits (500), Expect = 4e-52
Identities = 125/402 (31%), Positives = 218/402 (54%), Gaps = 20/402 (4%)
Query: 249 VNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKP- 307
+N IKP+W KE+ ++++ FYK S D P +H+ + ++ +SIL+VP P
Sbjct: 336 MNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPR 395
Query: 308 GLFEL--SRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNS 365
GLF+ S+ SD + LY R++ I +++PK+L FVKGVVDS+D+PLN+SRE LQ
Sbjct: 396 GLFDEYGSKKSDY-IKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 454
Query: 366 ALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLL 425
L+ +R L + L + +++ D + F+K++ +K G++ S + +AKLL
Sbjct: 455 KLLKVIRKKLVRKTLDMIKKIA--DDKYNDTFWKEFGTNIKLGVIEDHS--NRTRLAKLL 510
Query: 426 RFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCY 485
RF+SS TSL Y R K+ Q I+++A SR+ AE+SP+ E L K+ EV++
Sbjct: 511 RFQSSHHPT-DITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLT 569
Query: 486 EMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTN-L 544
E DE + L EF G+ +V + + D+SE S + + + L++++K L
Sbjct: 570 EPVDEYCIQALPEFDGKRFQNVAKEGVK--FDESEKTKESREAVEKEFEPLLNWMKDKAL 627
Query: 545 TGKVFDVRTTQKLDSHPCVIVVPEMAAA---RHFIRTQAQNLTEE---NRFALLRPQLEI 598
K+ +Q+L PC +V + + ++ QA ++ N +A + EI
Sbjct: 628 KDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEI 687
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM 638
N +HP+++ + + + D++ T+ +A LF A + +G ++
Sbjct: 688 NPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLL 729
Score = 175 bits (427), Expect = 3e-43
Identities = 93/245 (37%), Positives = 153/245 (62%), Gaps = 12/245 (4%)
Query: 30 LKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGN 89
L+ KSEK FQAE ++ ++ SLY +KE+F+RELISNASDAL+K R +S++ N
Sbjct: 69 LREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLT----DEN 124
Query: 90 LKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEI--KKQG 147
+ L +++ DK+ + D+G+GMT+EEL +NLGTIA+SG+ F+ ++ ++
Sbjct: 125 ALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQED 184
Query: 148 AEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI- 206
+ S +IGQFGVGFYSAF+VADK+ + T D+ + W SD + I + G +
Sbjct: 185 GQSTSELIGQFGVGFYSAFLVADKV-IVTSKHNNDTQ-HIWESDSNEFSVIADPRGNTLG 242
Query: 207 -GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GT I + LK + ++ + DT+K+++KKYS F++ PI++ + + +++ E +E +
Sbjct: 243 RGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEE--PMEEEEAAK 300
Query: 266 EQHIE 270
E+ E
Sbjct: 301 EEKEE 305
>AY040226-1|AAK74072.1| 782|Homo sapiens heat shock protein gp96
precursor protein.
Length = 782
Score = 205 bits (500), Expect = 4e-52
Identities = 125/402 (31%), Positives = 218/402 (54%), Gaps = 20/402 (4%)
Query: 249 VNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKP- 307
+N IKP+W KE+ ++++ FYK S D P +H+ + ++ +SIL+VP P
Sbjct: 315 MNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPR 374
Query: 308 GLFEL--SRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNS 365
GLF+ S+ SD + LY R++ I +++PK+L FVKGVVDS+D+PLN+SRE LQ
Sbjct: 375 GLFDEYGSKKSDY-IKLYVRRVFIPDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 433
Query: 366 ALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLL 425
L+ +R L + L + +++ D + F+K++ +K G++ S + +AKLL
Sbjct: 434 KLLKVIRKKLVRKTLDMIKKIA--DDKYNDTFWKEFGTNIKLGVIEDHS--NRTRLAKLL 489
Query: 426 RFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCY 485
RF+SS TSL Y R K+ Q I+++A SR+ AE+SP+ E L K+ EV++
Sbjct: 490 RFQSSHHPT-DITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLT 548
Query: 486 EMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTN-L 544
E DE + L EF G+ +V + + D+SE S + + + L++++K L
Sbjct: 549 EPVDEYCIQALPEFDGKRFQNVAKEGVK--FDESEKTKESREAVEKEFEPLLNWMKDKAL 606
Query: 545 TGKVFDVRTTQKLDSHPCVIVVPEMAAA---RHFIRTQAQNLTEE---NRFALLRPQLEI 598
K+ +Q+L PC +V + + ++ QA ++ N +A + EI
Sbjct: 607 KDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEI 666
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM 638
N +HP+++ + + + D++ T+ +A LF A + +G ++
Sbjct: 667 NPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLL 708
Score = 176 bits (428), Expect = 2e-43
Identities = 93/245 (37%), Positives = 154/245 (62%), Gaps = 12/245 (4%)
Query: 30 LKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGN 89
L+ KSEK FQAE ++ ++ SLY +KE+F+RELISNASDAL+K R +S++ N
Sbjct: 48 LREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLT----DEN 103
Query: 90 LKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEI--KKQG 147
+ L +++ DK+ + D+G+GMT+EEL +NLGTIA+SG+ F+ ++ ++
Sbjct: 104 ALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQED 163
Query: 148 AEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI- 206
+ +S +IGQFGVGFYSAF+VADK+ + T D+ + W SD + I + G +
Sbjct: 164 GQSSSELIGQFGVGFYSAFLVADKV-IVTSKHNNDTQ-HIWESDSNEFSVIADPRGNTLG 221
Query: 207 -GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GT I + LK + ++ + DT+K+++KKYS F++ PI++ + + +++ E +E +
Sbjct: 222 RGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEE--PMEEEEAAK 279
Query: 266 EQHIE 270
E+ E
Sbjct: 280 EEKEE 284
>AJ890084-1|CAI64497.1| 802|Homo sapiens tumor rejection antigen
(gp96) 1 protein.
Length = 802
Score = 205 bits (500), Expect = 4e-52
Identities = 125/402 (31%), Positives = 218/402 (54%), Gaps = 20/402 (4%)
Query: 249 VNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKP- 307
+N IKP+W KE+ ++++ FYK S D P +H+ + ++ +SIL+VP P
Sbjct: 336 MNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPR 395
Query: 308 GLFEL--SRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNS 365
GLF+ S+ SD + LY R++ I +++PK+L FVKGVVDS+D+PLN+SRE LQ
Sbjct: 396 GLFDEYGSKKSDY-IKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 454
Query: 366 ALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLL 425
L+ +R L + L + +++ D + F+K++ +K G++ S + +AKLL
Sbjct: 455 KLLKVIRKKLVRKTLDMIKKIA--DDKYNDTFWKEFGTNIKLGVIEDHS--NRTRLAKLL 510
Query: 426 RFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCY 485
RF+SS TSL Y R K+ Q I+++A SR+ AE+SP+ E L K+ EV++
Sbjct: 511 RFQSSHHPT-DITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLT 569
Query: 486 EMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTN-L 544
E DE + L EF G+ +V + + D+SE S + + + L++++K L
Sbjct: 570 EPVDEYCIQALPEFDGKRFQNVAKEGVK--FDESEKTKESREAVEKEFEPLLNWMKDKAL 627
Query: 545 TGKVFDVRTTQKLDSHPCVIVVPEMAAA---RHFIRTQAQNLTEE---NRFALLRPQLEI 598
K+ +Q+L PC +V + + ++ QA ++ N +A + EI
Sbjct: 628 KDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEI 687
Query: 599 NAKHPIVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM 638
N +HP+++ + + + D++ T+ +A LF A + +G ++
Sbjct: 688 NPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLL 729
Score = 175 bits (427), Expect = 3e-43
Identities = 93/245 (37%), Positives = 153/245 (62%), Gaps = 12/245 (4%)
Query: 30 LKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGN 89
L+ KSEK FQAE ++ ++ SLY +KE+F+RELISNASDAL+K R +S++ N
Sbjct: 69 LREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLT----DEN 124
Query: 90 LKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEI--KKQG 147
+ L +++ DK+ + D+G+GMT+EEL +NLGTIA+SG+ F+ ++ ++
Sbjct: 125 ALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQED 184
Query: 148 AEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI- 206
+ S +IGQFGVGFYSAF+VADK+ + T D+ + W SD + I + G +
Sbjct: 185 GQSTSELIGQFGVGFYSAFLVADKV-IVTSKHNNDTQ-HIWESDSNEFSVIADPRGNTLG 242
Query: 207 -GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GT I + LK + ++ + DT+K+++KKYS F++ PI++ + + +++ E +E +
Sbjct: 243 RGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEE--PMEEEEAAK 300
Query: 266 EQHIE 270
E+ E
Sbjct: 301 EEKEE 305
>BC007989-1|AAH07989.2| 422|Homo sapiens HSP90AA1 protein protein.
Length = 422
Score = 198 bits (482), Expect = 7e-50
Identities = 121/386 (31%), Positives = 211/386 (54%), Gaps = 17/386 (4%)
Query: 270 EFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKP-GLFELSRDSDVGVALYSRKIL 328
EFYK ++N ++ H+ + L R++L+VP P LFE +R + LY R++
Sbjct: 1 EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFE-NRKKKNNIKLYVRRVF 59
Query: 329 IKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQ 388
I E ++P++L F++GVVDSED+PLN+SRE+LQ S ++ +R L + L+ E+++
Sbjct: 60 IMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAE 119
Query: 389 KDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQK 448
D Y+ FY+ +S +K GI + ++++++LLR+ +S S + SL DY +R K
Sbjct: 120 -DKENYKKFYEQFSKNIKLGI--HEDSQNRKKLSELLRYYTS-ASGDEMVSLKDYCTRMK 175
Query: 449 DDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVE 508
++QK I+Y+ +++ S + E L+K +EV++ E DE + +LKEF G+ LVSV
Sbjct: 176 ENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVT 235
Query: 509 NDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE 568
+ P D+ E E ++++ + L +K L KV V + +L + PC IV
Sbjct: 236 KEGLELPEDEEEKKKQEE--KKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTST 293
Query: 569 MAAARHFIR-TQAQNLTEENRFALL--RPQLEINAKHPIVKKLHKLMSTDKELATM--VA 623
+ R +AQ L + + + + LEIN H I++ L + DK ++ +
Sbjct: 294 YGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLV 353
Query: 624 QQLFSNAMVTAGLVM-DPRNLITHIN 648
L+ A++++G + DP+ TH N
Sbjct: 354 ILLYETALLSSGFSLEDPQ---THAN 376
>BC108695-1|AAI08696.1| 585|Homo sapiens HSP90AA1 protein protein.
Length = 585
Score = 195 bits (475), Expect = 5e-49
Identities = 101/306 (33%), Positives = 179/306 (58%), Gaps = 8/306 (2%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYV 302
+++ +++N KP+W P +IT E++ EFYK ++N ++ H+ + L R++L+V
Sbjct: 284 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 343
Query: 303 PEGKP-GLFELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL 361
P P LFE +R + LY R++ I E ++P++L F++GVVDSED+PLN+SRE+
Sbjct: 344 PRRAPFDLFE-NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREM 402
Query: 362 LQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEI 421
LQ S ++ +R L + L+ E+++ D Y+ FY+ +S +K GI + ++++
Sbjct: 403 LQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGI--HEDSQNRKKL 459
Query: 422 AKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEV 481
++LLR+ +S S + SL DY +R K++QK I+Y+ +++ S + E L+K +EV
Sbjct: 460 SELLRYYTS-ASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEV 518
Query: 482 LFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLK 541
++ E DE + +LKEF G+ LVSV + P D+ E E ++++ + L +K
Sbjct: 519 IYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEE--KKTKFENLCKIMK 576
Query: 542 TNLTGK 547
L K
Sbjct: 577 DILEKK 582
Score = 184 bits (447), Expect = 1e-45
Identities = 97/225 (43%), Positives = 148/225 (65%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K RY S+
Sbjct: 5 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESL 64
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
+ + + KEL I L +KQ+RT+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 65 TDPSKLDSGKEL----HINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 121 ALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 175
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 176 TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 220
>X07270-1|CAA30255.1| 312|Homo sapiens protein ( Human mRNA for
heat shock protein hsp86. ).
Length = 312
Score = 184 bits (447), Expect = 1e-45
Identities = 97/225 (43%), Positives = 148/225 (65%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K RY S+
Sbjct: 5 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESL 64
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
+ + + KEL I L +KQ+RT+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 65 TDPSKLDSGKEL----HINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 121 ALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 175
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 176 TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 220
Score = 32.3 bits (70), Expect = 5.6
Identities = 10/29 (34%), Positives = 20/29 (68%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEF 271
+++ +++N KP+W P +IT E++ EF
Sbjct: 284 YIDQEELNKTKPIWTRNPDDITNEEYGEF 312
>M30626-1|AAA36023.1| 312|Homo sapiens heat shock protein 86
protein.
Length = 312
Score = 184 bits (447), Expect = 1e-45
Identities = 97/225 (43%), Positives = 148/225 (65%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K RY S+
Sbjct: 5 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESL 64
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
+ + + KEL I L +KQ+RT+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 65 TDPSKLDSGKEL----HINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 121 ALQA-GAD--ISMIGQFGVGFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 175
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S F+ PI L
Sbjct: 176 TGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITL 220
Score = 32.3 bits (70), Expect = 5.6
Identities = 10/29 (34%), Positives = 20/29 (68%)
Query: 243 FLNNDQVNSIKPLWLFEPKEITQEQHIEF 271
+++ +++N KP+W P +IT E++ EF
Sbjct: 284 YIDQEELNKTKPIWTRNPDDITNEEYGEF 312
>BC007327-1|AAH07327.1| 351|Homo sapiens HSP90AB1 protein protein.
Length = 351
Score = 180 bits (438), Expect = 1e-44
Identities = 94/208 (45%), Positives = 141/208 (67%), Gaps = 11/208 (5%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL +
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL----K 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+T D+GIGMTK +L NLGTIA+SG+K+F+E ++ GA+ S+IGQF
Sbjct: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA-GAD--ISMIGQF 129
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
GVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK++++LK
Sbjct: 130 GVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPIFL 244
D E+ ++ VK ++KK+S F+ PI L
Sbjct: 188 DQTEYLEERRVKEVVKKHSQFIGYPITL 215
Score = 60.9 bits (141), Expect = 1e-08
Identities = 28/90 (31%), Positives = 50/90 (55%), Gaps = 3/90 (3%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKP 282
+DD+ K KK +++ +++N KP+W P +ITQE++ EFYK ++N ++
Sbjct: 258 EDDSGKDKKKKTKKIKEK--YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDH 315
Query: 283 RFTLHYKTDAPLSIRSILYVPEGKP-GLFE 311
H+ + L R++L++P P LFE
Sbjct: 316 LAVKHFSVEGQLEFRALLFIPRRAPFDLFE 345
>AY956764-1|AAX38251.1| 597|Homo sapiens heat shock protein 90Bc
protein.
Length = 597
Score = 180 bits (438), Expect = 1e-44
Identities = 125/424 (29%), Positives = 216/424 (50%), Gaps = 64/424 (15%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLE 98
FQAE L+ ++ + YS++E+F++ELISNASDAL+K RY S++ + + KE L+
Sbjct: 17 FQAEIAQLISLIINTFYSNEEIFLQELISNASDALDKIRYESLTDPSKLDSGKE----LK 72
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I + + Q RT+ D+GIGMTK +L NL TIA+SG+K+ +E ++
Sbjct: 73 IDIIPNPQERTLALVDTGIGMTKADLINNLRTIAKSGTKACMEALQ-------------- 118
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKIVVYLKT 216
A+K+ V T+ + D Y W S G++ + G I GTK++++LK
Sbjct: 119 ----------AEKLVVITKHN--DDEQYAWESSAGGSFTVHADHGEPIGRGTKVILHLKE 166
Query: 217 DCREFADDDTVKSIIKKYSNFVSSPI--FLNNDQVNSIKPLWLFEPK------------- 261
D E+ ++ VK ++KK+S F+ PI +L +Q I E K
Sbjct: 167 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEQDKEISDDEAEEEKGEKEEEDKDDEEK 226
Query: 262 ----------EITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKP-GLF 310
E +++ EFYK +++ ++ H+ + L R++L+ P P LF
Sbjct: 227 PKIKDVGSDEEDDSKEYGEFYKSLTSDWEDHLAVKHFSVEGQLEFRALLFSPRRAPFDLF 286
Query: 311 ELSRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITK 370
E + + + LY R++ I + ++P++L F+ GVVDSED+PLN+SRE+LQ S ++
Sbjct: 287 ENKKKKN-NIKLYVRRVFIMDSCDELIPEYLNFIHGVVDSEDLPLNISREMLQQSKILKY 345
Query: 371 LRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEG--IVTSQSPLEKEEIAKLLRFE 428
+ + + + + K+ + AF + K+G +V P+++ + +L F+
Sbjct: 346 VSHMKETQKSTYYITGESKEQVANSAFVERVR---KQGFEVVYMTEPIDEYCVQQLKEFD 402
Query: 429 SSKL 432
L
Sbjct: 403 GKSL 406
Score = 95.9 bits (228), Expect = 4e-19
Identities = 64/222 (28%), Positives = 107/222 (48%), Gaps = 8/222 (3%)
Query: 436 QRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLE 495
Q++ + Y S K+ QKS +Y+ S+E S + E ++K+ EV++ E DE + +
Sbjct: 338 QQSKILKYVSHMKETQKSTYYITGESKEQVANSAFVERVRKQGFEVVYMTEPIDEYCVQQ 397
Query: 496 LKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQ 555
LKEF G++LVSV + P D+ E E + + + L +K L KV V +
Sbjct: 398 LKEFDGKSLVSVTKEGLELPEDEEEKKKMEE--SKEKFENLCKLMKEILDKKVEKVTISN 455
Query: 556 KLDSHPCVIVVPE---MAAARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLM 612
+L S PC IV A ++ QA + + + LEIN HPI++ L +
Sbjct: 456 RLVSSPCCIVTSTYGWTANMEQIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKA 515
Query: 613 STDK--ELATMVAQQLFSNAMVTAGLVM-DPRNLITHINDLL 651
DK + + LF A++++G + DP+ HI ++
Sbjct: 516 EADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNHIYHMI 557
>BC009195-1|AAH09195.1| 315|Homo sapiens HSP90B1 protein protein.
Length = 315
Score = 175 bits (427), Expect = 3e-43
Identities = 93/245 (37%), Positives = 153/245 (62%), Gaps = 12/245 (4%)
Query: 30 LKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGN 89
L+ KSEK FQAE ++ ++ SLY +KE+F+RELISNASDAL+K R +S++ N
Sbjct: 69 LREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLT----DEN 124
Query: 90 LKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEI--KKQG 147
+ L +++ DK+ + D+G+GMT+EEL +NLGTIA+SG+ F+ ++ ++
Sbjct: 125 ALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQED 184
Query: 148 AEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI- 206
+ S +IGQFGVGFYSAF+VADK+ + T D+ + W SD + I + G +
Sbjct: 185 GQSTSELIGQFGVGFYSAFLVADKV-IVTSKHNNDTQ-HIWESDSNEFSVIADPRGNTLG 242
Query: 207 -GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GT I + LK + ++ + DT+K+++KKYS F++ PI++ + + +++ E +E +
Sbjct: 243 RGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEE--PMEEEEAAK 300
Query: 266 EQHIE 270
E+ E
Sbjct: 301 EEKEE 305
>AB209534-1|BAD92771.1| 576|Homo sapiens tumor rejection antigen
(gp96) 1 variant protein.
Length = 576
Score = 175 bits (427), Expect = 3e-43
Identities = 93/245 (37%), Positives = 153/245 (62%), Gaps = 12/245 (4%)
Query: 30 LKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGN 89
L+ KSEK FQAE ++ ++ SLY +KE+F+RELISNASDAL+K R +S++ N
Sbjct: 95 LREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLT----DEN 150
Query: 90 LKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEI--KKQG 147
+ L +++ DK+ + D+G+GMT+EEL +NLGTIA+SG+ F+ ++ ++
Sbjct: 151 ALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQED 210
Query: 148 AEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI- 206
+ S +IGQFGVGFYSAF+VADK+ + T D+ + W SD + I + G +
Sbjct: 211 GQSTSELIGQFGVGFYSAFLVADKV-IVTSKHNNDTQ-HIWESDSNEFSVIADPRGNTLG 268
Query: 207 -GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQ 265
GT I + LK + ++ + DT+K+++KKYS F++ PI++ + + +++ E +E +
Sbjct: 269 RGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEE--PMEEEEAAK 326
Query: 266 EQHIE 270
E+ E
Sbjct: 327 EEKEE 331
Score = 143 bits (347), Expect = 2e-33
Identities = 79/218 (36%), Positives = 127/218 (58%), Gaps = 9/218 (4%)
Query: 249 VNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKP- 307
+N IKP+W KE+ ++++ FYK S D P +H+ + ++ +SIL+VP P
Sbjct: 362 MNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPR 421
Query: 308 GLFEL--SRDSDVGVALYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNS 365
GLF+ S+ SD + LY R++ I +++PK+L FVKGVVDS+D+PLN+SRE LQ
Sbjct: 422 GLFDEYGSKKSDY-IKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQH 480
Query: 366 ALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLL 425
L+ +R L + L + +++ D + F+K++ +K G++ S + +AKLL
Sbjct: 481 KLLKVIRKKLVRKTLDMIKKIA--DDKYNDTFWKEFGTNIKLGVIEDHS--NRTRLAKLL 536
Query: 426 RFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSRE 463
RF+SS TSL Y R K+ Q I+++A SR+
Sbjct: 537 RFQSSHHPT-DITSLDQYVERMKEKQDKIYFMAGSSRK 573
>M30627-1|AAA36024.1| 312|Homo sapiens heat shock protein 86
protein.
Length = 312
Score = 175 bits (426), Expect = 4e-43
Identities = 93/225 (41%), Positives = 145/225 (64%), Gaps = 11/225 (4%)
Query: 22 TEKQSSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSV 81
T+ Q + + E FQAE L+ ++ + YS+KE+F+RELISN+SDAL+K Y S+
Sbjct: 5 TQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIWYESL 64
Query: 82 SSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE 141
+ + + KEL I L +KQ++T+T D+GIGMTK +L NLGTIA+SG+K+F+E
Sbjct: 65 TDPSKLDSGKEL----HINLIPNKQDQTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
Query: 142 EIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEA 201
++ GA+ S+IGQFGV FYSA++VA+K+ V T+ + D Y W S G++ ++
Sbjct: 121 ALQA-GAD--ISMIGQFGVSFYSAYLVAEKVTVITKHN--DDEQYAWESSAGGSFTVRTD 175
Query: 202 DGVEI--GTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
G + GTK++++LK D E+ ++ +K I+KK+S + PI L
Sbjct: 176 TGERMGRGTKVILHLKEDQTEYLEEQRIKEIVKKHSQLIGYPITL 220
>AK025370-1|BAB15121.1| 362|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21717 fis, clone COL10322. ).
Length = 362
Score = 173 bits (421), Expect = 2e-42
Identities = 108/321 (33%), Positives = 177/321 (55%), Gaps = 15/321 (4%)
Query: 334 ENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQ 393
+ ++P++L F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D
Sbjct: 5 DELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVEKCLELFSELAE-DKEN 63
Query: 394 YEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKS 453
Y+ FY+ +S LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKS
Sbjct: 64 YKKFYEAFSKNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKS 120
Query: 454 IFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQR 513
I+Y+ S+E S + E ++KR EV++ E DE + +LKEF G++LVSV +
Sbjct: 121 IYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLE 180
Query: 514 DPLDKSESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLDSHPCVIVVPE---MA 570
P D+ E E +++ + L +K L KV V + +L S PC IV A
Sbjct: 181 LPEDEEEKKKMEE--SKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA 238
Query: 571 AARHFIRTQAQNLTEENRFALLRPQLEINAKHPIVKKLHKLMSTDK--ELATMVAQQLFS 628
++ QA + + + LEIN HPIV+ L + DK + + LF
Sbjct: 239 NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE 298
Query: 629 NAMVTAGLVM-DPRNLITHIN 648
A++++G + DP+ TH N
Sbjct: 299 TALLSSGFSLEDPQ---THSN 316
>AY956769-1|AAX38256.1| 453|Homo sapiens heat shock protein 94c
protein.
Length = 453
Score = 146 bits (355), Expect = 2e-34
Identities = 100/339 (29%), Positives = 176/339 (51%), Gaps = 18/339 (5%)
Query: 280 DKPRFTLHYKTDAPLSIRSILYVPEGKP-GLFEL--SRDSDVGVALYSRKILIKSKAENI 336
D P +H+ T+ ++ +SIL+VP P GLF+ S+ SD + LY + I + ++
Sbjct: 122 DDPMAYIHFTTEGEVTFKSILFVPTSDPRGLFDEYGSKKSDY-IKLYVLCVFITDEFHDM 180
Query: 337 LPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEA 396
+PK+L FVKGVVDS+D+PLN+S E LQ L+ +R L + L + +++ + +
Sbjct: 181 MPKYLNFVKGVVDSDDLPLNVSLETLQQHKLLKVIRKKLVCKTLDKIKKIAGEK--YNDN 238
Query: 397 FYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFY 456
F+K++ +K G++ S + +AKLL F+SS T+L Y R K Q I++
Sbjct: 239 FWKEFGTNIKLGVIEDHS--NQTCLAKLLMFQSSHHPT-DITTLDQYVERMKGKQDKIYF 295
Query: 457 LAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPL 516
+A SR+ AE+ P E L K+ EV++ E DE + +F G+ +V + +
Sbjct: 296 MAGSSRKEAESPPSVERLLKKGCEVIYLTEPVDEHCIQAFPKFDGKRFQNVVKEGMK--F 353
Query: 517 DKSESIIGSEGLQQSQVDELISFLKTN-LTGKVFDVRTTQKLDSHPCVIVVPEMAAA--- 572
DKSE S + + + L++++K L K+ +Q L C +V + +
Sbjct: 354 DKSEKTKESHEAVEKEFEPLLNWMKDKALKDKIEKAVVSQHLTESLCALVASQYGRSGNT 413
Query: 573 RHFIRTQAQNLTEE---NRFALLRPQLEINAKHPIVKKL 608
++ QA +++ N +A + EIN +HP+++ +
Sbjct: 414 ERIMKAQAYQTSKDSSANYYASQKKTFEINPRHPLIRDM 452
>AY956765-1|AAX38252.1| 505|Homo sapiens heat shock protein 90Bd
protein.
Length = 505
Score = 139 bits (336), Expect = 3e-32
Identities = 76/194 (39%), Positives = 124/194 (63%), Gaps = 12/194 (6%)
Query: 47 LDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKELDRPLEIRLTTDKQ 106
+ ++ + YS+KE+F++ELISNASDAL+K RY S++ + KE L+I + + +
Sbjct: 1 MSLIINTFYSNKEIFLQELISNASDALDKIRYESLTDPSKLDGGKE----LKIDIIPNPR 56
Query: 107 NRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQFGVGFYSAF 166
+T ++GIGMTK +L NLG IA+SG+++F+E + AE S+IGQFGVGFYSA+
Sbjct: 57 ECILTLVNTGIGMTKADLINNLGAIAKSGTEAFMEAF-QSCAE--ISMIGQFGVGFYSAY 113
Query: 167 MVADKIEVFTRSSKGDSPGYQW-SSDGSG-TYEIQEADGVEIGTKIVVYLKTDCREFADD 224
+VA+K+ + + D Y W SS GS T + + ++ TK++++LK D E+ ++
Sbjct: 114 LVAEKVAI---TKHNDEEQYSWVSSAGSSFTLHVDHGEPIDRDTKVILHLKEDQTEYLEE 170
Query: 225 DTVKSIIKKYSNFV 238
VK ++KK+ F+
Sbjct: 171 RWVKEVVKKHPQFI 184
Score = 69.3 bits (162), Expect = 4e-11
Identities = 46/133 (34%), Positives = 67/133 (50%), Gaps = 2/133 (1%)
Query: 433 SNGQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELV 492
S + TSLS+Y S K+ QKSI + +E S + E K+ EV++ E DE
Sbjct: 370 SGDEMTSLSEYVSCMKEAQKSICDIIGECKEQVANSAFVEQEWKKGFEVIYMSEPIDEYC 429
Query: 493 LLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTNLTGKVFDVR 552
+ +LKEF G++L+SV + P D+ E I E + + L +K L KV V
Sbjct: 430 VQQLKEFDGKSLLSVTKEGLELPEDEEEKKIMEE--SNVKFENLCRLMKEILDKKVERVT 487
Query: 553 TTQKLDSHPCVIV 565
+ +L S PC IV
Sbjct: 488 ISSRLVSSPCRIV 500
Score = 42.3 bits (95), Expect = 0.005
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 223 DDDTVKSIIKKYSNFVSSPIFLNNDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYD 280
+DDT K+ KK + + +++N KP+W P +ITQE+ EFYK ++++++
Sbjct: 231 EDDTDKNNKKKTKKIKEK--YTDREELNQTKPIWTRNPDDITQEECGEFYKSLTSAWE 286
>AY956763-1|AAX38250.1| 422|Homo sapiens heat shock protein 90Bb
protein.
Length = 422
Score = 112 bits (269), Expect = 4e-24
Identities = 88/277 (31%), Positives = 139/277 (50%), Gaps = 30/277 (10%)
Query: 16 QHFSTVTEKQSSESLKGKSEKREF--QAETRMLLDIVARSLYSDKEVFIRELISNASDAL 73
+H +K E G+ E F QAE L+ ++ + YS+KE+F+ ELISNASDAL
Sbjct: 33 EHLRIGLKKMPEEVHLGEKEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDAL 92
Query: 74 EKFRYLSVSSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIAR 133
+K RY S++ + + KE L+I + + Q T+T D+GIGMTK +L NLGTIA+
Sbjct: 93 DKIRYESLTDPSKLDSGKE----LKIDIIPNTQEHTLTLVDTGIGMTKADLINNLGTIAK 148
Query: 134 -SGSKSFIEEIK-KQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSD 191
++EE++ K+ E+ S +G Y + +K K S G + +
Sbjct: 149 FQDQTEYLEEMQVKEVVEKHSQFLG------YPITLYLEK-----EREKEISDGK--AEE 195
Query: 192 GSGTYEIQEADGVEIGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQVNS 251
G E + D E KI D +DD+ K KK +++ +++N
Sbjct: 196 EKGEKEEENKDDEE-KPKI-----EDVGSDEEDDSGKDKKKKTKKIKEK--YIDQEELNK 247
Query: 252 IKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHY 288
KP+W ++ITQE++ EFYK ++N + K + Y
Sbjct: 248 TKPIWTRNTEDITQEEYGEFYKSLTNDW-KDHLAVRY 283
Score = 69.3 bits (162), Expect = 4e-11
Identities = 45/127 (35%), Positives = 67/127 (52%), Gaps = 5/127 (3%)
Query: 439 SLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKE 498
S+ +Y SR K+ QKSI+Y+ S+E S + E + KRD V++ E D +LKE
Sbjct: 285 SVEEYVSRMKEIQKSIYYITGESKEQVANSAFVEQVWKRDSRVVYMTEPIDG---YQLKE 341
Query: 499 FGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTNLTGKVFDVRTTQKLD 558
F G++LVSV + P D E E ++++ + L F+K L KV V + +L
Sbjct: 342 FDGKSLVSVTKEGLELPEDGEEKKRMEE--RKAKFENLCKFMKETLDKKVEMVTVSNRLV 399
Query: 559 SHPCVIV 565
S C IV
Sbjct: 400 SSSCCIV 406
>AY956768-1|AAX38255.1| 399|Homo sapiens heat shock protein 94b
protein.
Length = 399
Score = 103 bits (248), Expect = 2e-21
Identities = 96/368 (26%), Positives = 168/368 (45%), Gaps = 36/368 (9%)
Query: 265 QEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKP-GLFEL--SRDSDVGVA 321
++++ F K S D P +H+ + ++ +SIL+VP P GLF+ S+ SD +
Sbjct: 9 EDEYKAFCKSFSKESDDPVACIHFTAEGEVTFKSILFVPTFVPRGLFDEYGSKKSDY-IK 67
Query: 322 LYSRKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLK 381
LY R + I + +PK L FVKGVVDS + LN+S E LQ L+ +R L ++ L
Sbjct: 68 LYVRCVFITDDFRDTMPKNLNFVKGVVDSGGLSLNVSCETLQQHKLLKVIRKKLVHKTLD 127
Query: 382 FMVEMSQKDPLQYEAFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLS 441
+ +++ D + F+K++ +K G++ S + +AKLLRF+SS TSL
Sbjct: 128 MIKKIA--DEKYNDTFWKEFGTNIKLGVIEDHS--NRTCLAKLLRFQSSH-HPADITSLH 182
Query: 442 DYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGG 501
R K+ Q I +A EV++ E E + L EF G
Sbjct: 183 QDVERMKEKQDKICLMAG------------------GYEVIYLTEPVVEYCIQALPEFDG 224
Query: 502 RALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTN-LTGKVFDVRTTQKLDSH 560
+ +V + + D SE S + + + L +++K + K+ +Q L
Sbjct: 225 KRFQNVAKEGVK--FDDSEKTKESHEAVEKEFEPLPNWVKDKAIKDKIEKAMVSQCLTES 282
Query: 561 PCVIVVPEMAAA---RHFIRTQAQNL---TEENRFALLRPQLEINAKHPIVKKLHKLMST 614
C +V + + ++ QA N A + EIN +HP+++ + + +
Sbjct: 283 LCALVASQYGWSGNMERIMKAQAYQTGKGISTNYHASRKKTFEINPRHPLIRDMLRRIKE 342
Query: 615 DKELATMV 622
D++ T++
Sbjct: 343 DEDDKTVL 350
>D17804-1|BAA22050.1| 130|Homo sapiens heat shock protein beta
protein.
Length = 130
Score = 98.7 bits (235), Expect = 6e-20
Identities = 56/117 (47%), Positives = 80/117 (68%), Gaps = 9/117 (7%)
Query: 72 ALEKFRYLSVSSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTI 131
AL+K RY S++ + + KEL +I + + Q RT+T D+GIGMTK +L NLGTI
Sbjct: 1 ALDKIRYESLTDPSKLDSGKEL----KIDIIPNPQERTLTLVDTGIGMTKADLINNLGTI 56
Query: 132 ARSGSKSFIEEIKKQGAEQASSIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQW 188
A+SG+K+F+E + + GA+ SIIGQFGVGFYSA++VA+K+ V T+ + D Y W
Sbjct: 57 AKSGTKAFMEAL-QLGAD--ISIIGQFGVGFYSAYLVAEKVVVITKHN--DDEQYAW 108
>AL139392-5|CAI20097.1| 149|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), classTB (POZ) domain containing pro
protein.
Length = 149
Score = 98.3 bits (234), Expect = 8e-20
Identities = 51/130 (39%), Positives = 83/130 (63%), Gaps = 4/130 (3%)
Query: 343 FVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYS 402
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +S
Sbjct: 1 FIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFS 59
Query: 403 IFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSR 462
LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S+
Sbjct: 60 KNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGESK 116
Query: 463 ELAETSPYYE 472
E S + E
Sbjct: 117 EQVANSAFVE 126
>AL139392-4|CAI20096.1| 141|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), classmain protein.
Length = 141
Score = 95.5 bits (227), Expect = 5e-19
Identities = 49/121 (40%), Positives = 80/121 (66%), Gaps = 4/121 (3%)
Query: 343 FVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYS 402
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +S
Sbjct: 1 FIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFS 59
Query: 403 IFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPSR 462
LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+ S+
Sbjct: 60 KNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGESK 116
Query: 463 E 463
E
Sbjct: 117 E 117
>AL139392-6|CAI20098.1| 170|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), classnit 8 homolog (S. cerevisiae)
protein.
Length = 170
Score = 91.5 bits (217), Expect = 9e-18
Identities = 47/115 (40%), Positives = 77/115 (66%), Gaps = 4/115 (3%)
Query: 343 FVKGVVDSEDIPLNLSRELLQNSALITKLRTVLTNRFLKFMVEMSQKDPLQYEAFYKDYS 402
F++GVVDSED+PLN+SRE+LQ S ++ +R + + L+ E+++ D Y+ FY+ +S
Sbjct: 1 FIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFS 59
Query: 403 IFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYL 457
LK GI + + +++LLR+ +S+ S + TSLS+Y SR K+ QKSI+Y+
Sbjct: 60 KNLKLGI--HEDSTNRRRLSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYI 111
>AY956760-1|AAX38247.1| 418|Homo sapiens heat shock protein 90Ad
protein.
Length = 418
Score = 87.4 bits (207), Expect = 1e-16
Identities = 46/98 (46%), Positives = 66/98 (67%), Gaps = 5/98 (5%)
Query: 99 IRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIEEIKKQGAEQASSIIGQF 158
I L +KQ+RT+T D+GIGMTK +L NLGTI +S +K F+E + + GA+ S+IGQF
Sbjct: 18 ISLIPNKQDRTLTIVDTGIGMTKADLINNLGTITKSETKVFME-VLQAGAD--ISMIGQF 74
Query: 159 GVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTY 196
VGFYSA+ VA+K+ V T+ + + Y W S G++
Sbjct: 75 SVGFYSAYSVAEKVTVITKHNNDEQ--YAWESSLRGSF 110
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/110 (34%), Positives = 65/110 (59%), Gaps = 7/110 (6%)
Query: 267 QHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKPGLFEL--SRDSDVGVALYS 324
++ EFYK ++ +++ H+ + L R+ L+VP P FEL +R + L +
Sbjct: 112 EYREFYKSLTINWEDYLAVKHFSVEGQLEFRAFLFVPRLAP--FELLETRKKKNKIKLSA 169
Query: 325 RKILIKSKAENILPKWLRFVKGVVDSEDIPLNLSREL---LQNSALITKL 371
R+ LI E ++P++L F++GVVDSED+PLN+ RE + NS ++ +L
Sbjct: 170 RRDLIMDNCEELIPEYLNFIRGVVDSEDLPLNIFRETKDQVANSTIVQRL 219
Score = 41.9 bits (94), Expect = 0.007
Identities = 23/72 (31%), Positives = 38/72 (52%)
Query: 461 SRELAETSPYYESLKKRDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSE 520
+++ S + L K +EV++ E DE + +LKEF G+ LVSV + P D+ E
Sbjct: 206 TKDQVANSTIVQRLWKHGLEVIYTIEPIDEYCVQQLKEFEGKTLVSVTKEDLELPEDEEE 265
Query: 521 SIIGSEGLQQSQ 532
EG Q+++
Sbjct: 266 KKKQEEGKQKTK 277
>AL139392-2|CAI20094.1| 168|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), classr 11 protein.
Length = 168
Score = 85.8 bits (203), Expect = 4e-16
Identities = 40/94 (42%), Positives = 62/94 (65%), Gaps = 4/94 (4%)
Query: 153 SIIGQFGVGFYSAFMVADKIEVFTRSSKGDSPGYQWSSDGSGTYEIQEADGVEI--GTKI 210
S+IGQFGVGFYSA++VA+K+ V T+ + D Y W S G++ ++ G I GTK+
Sbjct: 76 SMIGQFGVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKV 133
Query: 211 VVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFL 244
+++LK D E+ ++ VK ++KK+S F+ PI L
Sbjct: 134 ILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITL 167
Score = 60.5 bits (140), Expect = 2e-08
Identities = 28/55 (50%), Positives = 40/55 (72%)
Query: 39 FQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVPESGNLKEL 93
FQAE L+ ++ + YS+KE+F+RELISNASDAL+K RY S++ + + KEL
Sbjct: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL 71
>S70561-1|AAD14062.1| 68|Homo sapiens 90-kda heat shock protein
beta HSP90 beta protein.
Length = 68
Score = 61.3 bits (142), Expect = 1e-08
Identities = 32/72 (44%), Positives = 49/72 (68%), Gaps = 4/72 (5%)
Query: 73 LEKFRYLSVSSVPESGNLKELDRPLEIRLTTDKQNRTITFQDSGIGMTKEELTQNLGTIA 132
L+K RY S++ + + KEL +I + + Q RT+T D+GIGMTK +L NLGTIA
Sbjct: 1 LDKIRYESLTDPSKLDSGKEL----KIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIA 56
Query: 133 RSGSKSFIEEIK 144
+SG+K+F+E ++
Sbjct: 57 KSGTKAFMEALQ 68
>AY956767-1|AAX38254.1| 361|Homo sapiens heat shock protein 90Bf
protein.
Length = 361
Score = 56.0 bits (129), Expect = 4e-07
Identities = 41/156 (26%), Positives = 75/156 (48%), Gaps = 8/156 (5%)
Query: 190 SDGSGTYEIQEADGVEIGTKIVVYLKTDCREFADDDTVKSIIKKYSNFVSSPIFLNNDQV 249
S+ G E +A G +I ++V L + +DD+ K KK ++N +++
Sbjct: 73 SETKGFMEALQA-GADIS--MIVNLIENVGSNEEDDSGKDKKKKTEKIKEK--YINQEEL 127
Query: 250 NSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPLSIRSILYVPEGKP-G 308
N IK +W ITQE + EF +N ++ H+ + L R++L++P P
Sbjct: 128 NKIKTIWTRNHDYITQE-YGEFCNSHTNDWEDHLAVKHFSIEGQLEFRALLFIPYRAPFD 186
Query: 309 LFELSRDSDVGVALYSRKILIKSKAENILPKWLRFV 344
LFE +++ D + LY + I + ++P+ L F+
Sbjct: 187 LFENNKNKDT-IKLYVLHVFIVHSCDELIPEDLNFI 221
>AY956761-1|AAX38248.1| 334|Homo sapiens heat shock protein 90Ae
protein.
Length = 334
Score = 54.8 bits (126), Expect = 9e-07
Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Query: 435 GQRTSLSDYSSRQKDDQKSIFYLAAPSRELAETSPYYESLKKRDIEVLFCYEMYDELVLL 494
GQ L D K +QK I+Y+ +++ S + E L+K +EV++ E+ D+ +
Sbjct: 157 GQLEELKDSRRVMKANQKHIYYITGETKDQVANSAFVECLQKHGLEVIYMIELIDKYCVQ 216
Query: 495 ELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDELISFLKTNLTGKV 548
+LKE + +VSV + P D+ E E ++++ + L +K L KV
Sbjct: 217 QLKELESKTVVSVAKEGLELPEDEEEKKKQEE--KKTKFENLCKIMKDMLEKKV 268
Score = 37.1 bits (82), Expect = 0.20
Identities = 13/49 (26%), Positives = 28/49 (57%)
Query: 246 NDQVNSIKPLWLFEPKEITQEQHIEFYKFISNSYDKPRFTLHYKTDAPL 294
+ ++N KP+W P IT E++ EF++ ++N+++ H+ + L
Sbjct: 111 DQELNKTKPIWTRNPDAITNEEYGEFHQSLTNNWEDHLAVKHFSVEGQL 159
>BC029541-1|AAH29541.2| 277|Homo sapiens LETM2 protein protein.
Length = 277
Score = 35.5 bits (78), Expect = 0.60
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Query: 418 KEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS-RELAETSPYYESLKK 476
K E+AK L+ ++++ R + D S++ K + PS +E+ S +E +
Sbjct: 12 KLELAKFLQETMTEMARRNRAKMGDASTQLSSYVKQVQTGHKPSTKEIVRFSKLFED--Q 69
Query: 477 RDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDEL 536
+E L ++ LLEL+ FG L+ + M+ + + II EG+ V EL
Sbjct: 70 LALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSEL 129
>AY173945-1|AAO49715.1| 444|Homo sapiens leucine zipper-EF-hand
containing transmembrane protein 1-like protein protein.
Length = 444
Score = 35.5 bits (78), Expect = 0.60
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Query: 418 KEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS-RELAETSPYYESLKK 476
K E+AK L+ ++++ R + D S++ K + PS +E+ S +E +
Sbjct: 179 KLELAKFLQETMTEMARRNRAKMGDASTQLSSYVKQVQTGHKPSTKEIVRFSKLFED--Q 236
Query: 477 RDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDEL 536
+E L ++ LLEL+ FG L+ + M+ + + II EG+ V EL
Sbjct: 237 LALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSEL 296
>AK058138-1|BAB71680.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ25409 fis, clone TST03074. ).
Length = 396
Score = 35.5 bits (78), Expect = 0.60
Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Query: 418 KEEIAKLLRFESSKLSNGQRTSLSDYSSRQKDDQKSIFYLAAPS-RELAETSPYYESLKK 476
K E+AK L+ ++++ R + D S++ K + PS +E+ S +E +
Sbjct: 131 KLELAKFLQETMTEMARRNRAKMGDASTQLSSYVKQVQTGHKPSTKEIVRFSKLFED--Q 188
Query: 477 RDIEVLFCYEMYDELVLLELKEFGGRALVSVENDMQRDPLDKSESIIGSEGLQQSQVDEL 536
+E L ++ LLEL+ FG L+ + M+ + + II EG+ V EL
Sbjct: 189 LALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSEL 248
>BC019324-1|AAH19324.1| 525|Homo sapiens alanyl-tRNA synthetase
domain containing 1 protein.
Length = 525
Score = 33.5 bits (73), Expect = 2.4
Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 7/65 (10%)
Query: 196 YEIQEADGVEIGTKIVVYLKTDCREFADDDTVKSI---IKKYSNFVSSPIFLNNDQVNSI 252
+ + ADGVE+ +I Y K + ++ D + +SI ++K+ V+ P D I
Sbjct: 22 FSCKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTKED----I 77
Query: 253 KPLWL 257
KP+WL
Sbjct: 78 KPVWL 82
>BC004172-1|AAH04172.1| 525|Homo sapiens alanyl-tRNA synthetase
domain containing 1 protein.
Length = 525
Score = 33.5 bits (73), Expect = 2.4
Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 7/65 (10%)
Query: 196 YEIQEADGVEIGTKIVVYLKTDCREFADDDTVKSI---IKKYSNFVSSPIFLNNDQVNSI 252
+ + ADGVE+ +I Y K + ++ D + +SI ++K+ V+ P D I
Sbjct: 22 FSCKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTKED----I 77
Query: 253 KPLWL 257
KP+WL
Sbjct: 78 KPVWL 82
>D87666-2|BAA13431.1| 151|Homo sapiens heat shock protein 90
protein.
Length = 151
Score = 32.7 bits (71), Expect = 4.2
Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 9/108 (8%)
Query: 547 KVFDVRTTQKLDSHPCVIVVPEMAAARHFIRT-QAQNLTEENRFALL--RPQLEINAKHP 603
KV V + +L + PC IV + R +AQ L + + + + LEIN H
Sbjct: 1 KVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHS 60
Query: 604 IVKKLHKLMSTDKELATM--VAQQLFSNAMVTAGLVM-DPRNLITHIN 648
I++ L + DK ++ + L+ A++++G + DP+ TH N
Sbjct: 61 IIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQ---THAN 105
>AK127078-1|BAC86815.1| 844|Homo sapiens protein ( Homo sapiens
cDNA FLJ45135 fis, clone BRAWH3038252, highly similar
to Formin 1 isoform IV. ).
Length = 844
Score = 32.3 bits (70), Expect = 5.6
Identities = 36/145 (24%), Positives = 67/145 (46%), Gaps = 8/145 (5%)
Query: 389 KDPLQYE-AFYKDYSIFLKEGIVTSQSPLEKEEIAKLLRFESSKLSNGQRTSLSDYSSRQ 447
+DP ++E F KD + K+ + S++ +K ++ K+++ K S +S
Sbjct: 438 RDPSEFEYLFSKDTTQQKKKPL--SETYEKKNKVKKIIKLLDGKRSQTVGILISSLHLEM 495
Query: 448 KDDQKSIFYLAAPSRELAETSPYYESLKKRD--IEVLFCYE--MYDELVLLELKEFGGRA 503
KD Q++IF + +L + YE+ + D +++ YE +EL LL+ E
Sbjct: 496 KDIQQAIFNVDDSVVDLETLAALYENRAQEDELVKIRKYYETSKEEELKLLDKPEQFLHE 555
Query: 504 LVSVENDMQRDPLDKSESIIGSEGL 528
L + N +R S+ SEG+
Sbjct: 556 LAQIPNFAERAQCIIFRSVF-SEGI 579
>AL137254-1|CAB70656.1| 196|Homo sapiens hypothetical protein
protein.
Length = 196
Score = 31.5 bits (68), Expect = 9.8
Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 104 DKQNRTITFQDSGIGMTKEELTQNLGTIARSGSKSFIE--EIKKQGAEQASSIIGQFGVG 161
D++ ++T + + + E + +L I RSG SF E + K ++ +++I G
Sbjct: 133 DEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTTLINISGTQ 192
Query: 162 FYS 164
FYS
Sbjct: 193 FYS 195
>AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4
(KIAA1804) protein.
Length = 1036
Score = 31.5 bits (68), Expect = 9.8
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
+ E K K K +F+ L D SL SD F ++ AS L+K R L+ SS
Sbjct: 487 NQEKPKVKKRKGKFKRSRLKLKDGHRISLPSD---FQHKITVQASPNLDKRRSLNSSSSS 543
Query: 86 ESGNLKELDRPLEIRLTTDKQNRT 109
+ + R I+LT+D+ N+T
Sbjct: 544 PPSSPTMMPRLRAIQLTSDESNKT 567
>AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4beta
protein.
Length = 1036
Score = 31.5 bits (68), Expect = 9.8
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 26 SSESLKGKSEKREFQAETRMLLDIVARSLYSDKEVFIRELISNASDALEKFRYLSVSSVP 85
+ E K K K +F+ L D SL SD F ++ AS L+K R L+ SS
Sbjct: 487 NQEKPKVKKRKGKFKRSRLKLKDGHRISLPSD---FQHKITVQASPNLDKRRSLNSSSSS 543
Query: 86 ESGNLKELDRPLEIRLTTDKQNRT 109
+ + R I+LT+D+ N+T
Sbjct: 544 PPSSPTMMPRLRAIQLTSDESNKT 567
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.316 0.133 0.364
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 83,469,136
Number of Sequences: 224733
Number of extensions: 3374528
Number of successful extensions: 18777
Number of sequences better than 10.0: 72
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 18431
Number of HSP's gapped (non-prelim): 161
length of query: 658
length of database: 73,234,838
effective HSP length: 95
effective length of query: 563
effective length of database: 51,885,203
effective search space: 29211369289
effective search space used: 29211369289
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 68 (31.5 bits)
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