Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001235-TA|BGIBMGA001235-PA|IPR001474|GTP cyclohydrolase
I
(232 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z29434-1|CAB77392.1| 250|Homo sapiens GTP cyclohydrase I protein. 297 2e-80
U66097-1|AAD38868.1| 250|Homo sapiens GTP cyclohydrolase I prot... 297 2e-80
U19523-1|AAB16861.1| 250|Homo sapiens GTP cyclohydrolase I prot... 297 2e-80
S44049-1|AAB23164.1| 241|Homo sapiens GTP cyclohydrolase I prot... 297 2e-80
CR536551-1|CAG38788.1| 250|Homo sapiens GCH1 protein. 297 2e-80
BC025415-1|AAH25415.1| 250|Homo sapiens GTP cyclohydrolase 1 (d... 297 2e-80
AY137463-1|AAN17459.1| 177|Homo sapiens GTP cyclohydrolase I ty... 291 2e-78
Z16418-1|CAA78908.1| 183|Homo sapiens GTP cyclohydrolase I pro... 287 2e-77
U66095-1|AAD38866.1| 233|Homo sapiens GTP cyclohydrolase I prot... 221 1e-57
Z29433-1|CAB77391.1| 213|Homo sapiens GTP cyclohydrase I protein. 221 2e-57
S44053-1|AAB23165.1| 213|Homo sapiens GTP cyclohydrolase I prot... 221 2e-57
S43856-1|AAB23166.1| 209|Homo sapiens GTP cyclohydrolase I prot... 221 2e-57
AY137464-1|AAN17460.1| 158|Homo sapiens GTP cyclohydrolase I ty... 214 3e-55
U19259-1|AAB60633.1| 94|Homo sapiens GTP cyclohydrolase I prot... 161 2e-39
AY137465-1|AAN17461.1| 101|Homo sapiens GTP cyclohydrolase I ty... 153 4e-37
AF321276-1|AAK51704.1| 78|Homo sapiens GTP cyclohydrolase I pr... 139 9e-33
Z30952-1|CAA83213.1| 114|Homo sapiens GTP cyclohydrolase I prot... 63 9e-10
L29478-1|AAB42186.1| 114|Homo sapiens GTP cyclohydrolase I prot... 63 9e-10
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 31 4.5
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 31 4.5
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 31 4.5
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 31 4.5
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 30 5.9
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 30 5.9
BC107585-1|AAI07586.1| 385|Homo sapiens glucose-fructose oxidor... 30 7.9
AY358169-1|AAQ88536.1| 383|Homo sapiens LPGV9430 protein. 30 7.9
AK074382-1|BAB85066.1| 385|Homo sapiens protein ( Homo sapiens ... 30 7.9
>Z29434-1|CAB77392.1| 250|Homo sapiens GTP cyclohydrase I protein.
Length = 250
Score = 297 bits (730), Expect = 2e-80
Identities = 139/186 (74%), Positives = 164/186 (88%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 166 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTREEF 225
LTKQIA+A+T+A+RPAGV VV+E HMCMVMRGVQK+NSKTVTSTMLGVFR+DPKTREEF
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEF 244
Query: 226 LNLVHS 231
L L+ S
Sbjct: 245 LTLIRS 250
>U66097-1|AAD38868.1| 250|Homo sapiens GTP cyclohydrolase I
protein.
Length = 250
Score = 297 bits (730), Expect = 2e-80
Identities = 139/186 (74%), Positives = 164/186 (88%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 166 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTREEF 225
LTKQIA+A+T+A+RPAGV VV+E HMCMVMRGVQK+NSKTVTSTMLGVFR+DPKTREEF
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEF 244
Query: 226 LNLVHS 231
L L+ S
Sbjct: 245 LTLIRS 250
>U19523-1|AAB16861.1| 250|Homo sapiens GTP cyclohydrolase I
protein.
Length = 250
Score = 297 bits (730), Expect = 2e-80
Identities = 139/186 (74%), Positives = 164/186 (88%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 166 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTREEF 225
LTKQIA+A+T+A+RPAGV VV+E HMCMVMRGVQK+NSKTVTSTMLGVFR+DPKTREEF
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEF 244
Query: 226 LNLVHS 231
L L+ S
Sbjct: 245 LTLIRS 250
>S44049-1|AAB23164.1| 241|Homo sapiens GTP cyclohydrolase I
protein.
Length = 241
Score = 297 bits (730), Expect = 2e-80
Identities = 139/186 (74%), Positives = 164/186 (88%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 56 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 115
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 116 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 175
Query: 166 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTREEF 225
LTKQIA+A+T+A+RPAGV VV+E HMCMVMRGVQK+NSKTVTSTMLGVFR+DPKTREEF
Sbjct: 176 LTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEF 235
Query: 226 LNLVHS 231
L L+ S
Sbjct: 236 LTLIRS 241
>CR536551-1|CAG38788.1| 250|Homo sapiens GCH1 protein.
Length = 250
Score = 297 bits (730), Expect = 2e-80
Identities = 139/186 (74%), Positives = 164/186 (88%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 166 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTREEF 225
LTKQIA+A+T+A+RPAGV VV+E HMCMVMRGVQK+NSKTVTSTMLGVFR+DPKTREEF
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEF 244
Query: 226 LNLVHS 231
L L+ S
Sbjct: 245 LTLIRS 250
>BC025415-1|AAH25415.1| 250|Homo sapiens GTP cyclohydrolase 1
(dopa-responsive dystonia) protein.
Length = 250
Score = 297 bits (730), Expect = 2e-80
Identities = 139/186 (74%), Positives = 164/186 (88%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 166 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTREEF 225
LTKQIA+A+T+A+RPAGV VV+E HMCMVMRGVQK+NSKTVTSTMLGVFR+DPKTREEF
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEF 244
Query: 226 LNLVHS 231
L L+ S
Sbjct: 245 LTLIRS 250
>AY137463-1|AAN17459.1| 177|Homo sapiens GTP cyclohydrolase I type
IV protein.
Length = 177
Score = 291 bits (713), Expect = 2e-78
Identities = 135/177 (76%), Positives = 158/177 (89%)
Query: 55 SYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVK 114
+Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDED DEMV+VK
Sbjct: 1 AYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVK 60
Query: 115 DIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAV 174
DI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQERLTKQIA+A+
Sbjct: 61 DIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAI 120
Query: 175 TQAVRPAGVAVVIEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTREEFLNLVHS 231
T+A+RPAGV VV+E HMCMVMRGVQK+NSKTVTSTMLGVFR+DPKTREEFL L+ S
Sbjct: 121 TEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS 177
>Z16418-1|CAA78908.1| 183|Homo sapiens GTP cyclohydrolase I
protein.
Length = 183
Score = 287 bits (705), Expect = 2e-77
Identities = 135/178 (75%), Positives = 158/178 (88%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 6 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 65
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 66 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 125
Query: 166 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVQKINSKTVTSTMLGVFRDDPKTRE 223
LTKQIA+A+T+A+RPAGV VVIE HMCMVMRGVQK+NSKTVTSTMLGVFR+DPKTRE
Sbjct: 126 LTKQIAVAITEALRPAGVGVVIEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTRE 183
>U66095-1|AAD38866.1| 233|Homo sapiens GTP cyclohydrolase I
protein.
Length = 233
Score = 221 bits (541), Expect = 1e-57
Identities = 105/159 (66%), Positives = 130/159 (81%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 166 LTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVQKINS 204
LTKQIA+A+T+A+RPAGV VV+E +G+ + S
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVEATKSNKYNKGLSPLLS 223
>Z29433-1|CAB77391.1| 213|Homo sapiens GTP cyclohydrase I protein.
Length = 213
Score = 221 bits (539), Expect = 2e-57
Identities = 103/143 (72%), Positives = 125/143 (87%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 166 LTKQIAIAVTQAVRPAGVAVVIE 188
LTKQIA+A+T+A+RPAGV VV+E
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVE 207
>S44053-1|AAB23165.1| 213|Homo sapiens GTP cyclohydrolase I
protein.
Length = 213
Score = 221 bits (539), Expect = 2e-57
Identities = 103/143 (72%), Positives = 125/143 (87%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 166 LTKQIAIAVTQAVRPAGVAVVIE 188
LTKQIA+A+T+A+RPAGV VV+E
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVE 207
>S43856-1|AAB23166.1| 209|Homo sapiens GTP cyclohydrolase I
protein.
Length = 209
Score = 221 bits (539), Expect = 2e-57
Identities = 103/143 (72%), Positives = 125/143 (87%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDE 105
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDE
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDE 124
Query: 106 DTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQER 165
D DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQER
Sbjct: 125 DHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQER 184
Query: 166 LTKQIAIAVTQAVRPAGVAVVIE 188
LTKQIA+A+T+A+RPAGV VV+E
Sbjct: 185 LTKQIAVAITEALRPAGVGVVVE 207
>AY137464-1|AAN17460.1| 158|Homo sapiens GTP cyclohydrolase I type
V protein.
Length = 158
Score = 214 bits (522), Expect = 3e-55
Identities = 99/134 (73%), Positives = 119/134 (88%)
Query: 55 SYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVK 114
+Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDED DEMV+VK
Sbjct: 1 AYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVK 60
Query: 115 DIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAV 174
DI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+SRRLQVQERLTKQIA+A+
Sbjct: 61 DIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAI 120
Query: 175 TQAVRPAGVAVVIE 188
T+A+RPAGV VV+E
Sbjct: 121 TEALRPAGVGVVVE 134
>U19259-1|AAB60633.1| 94|Homo sapiens GTP cyclohydrolase I
protein.
Length = 94
Score = 161 bits (391), Expect = 2e-39
Identities = 75/92 (81%), Positives = 86/92 (93%)
Query: 97 VLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVEIF 156
VLN+AIFDED DEMV+VKDI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLARIVEI+
Sbjct: 1 VLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIY 60
Query: 157 SRRLQVQERLTKQIAIAVTQAVRPAGVAVVIE 188
SRRLQVQERLTKQIA+A+T+A+RPAGV VV+E
Sbjct: 61 SRRLQVQERLTKQIAVAITEALRPAGVGVVVE 92
>AY137465-1|AAN17461.1| 101|Homo sapiens GTP cyclohydrolase I type
VI protein.
Length = 101
Score = 153 bits (372), Expect = 4e-37
Identities = 70/100 (70%), Positives = 84/100 (84%)
Query: 55 SYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVK 114
+Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++ +VLN+AIFDED DEMV+VK
Sbjct: 1 AYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVK 60
Query: 115 DIEMFSMCEHHLVPFYGKVSIGYLPQGKILGLSKLARIVE 154
DI+MFSMCEHHLVPF GKV IGYLP ++LGLSKLAR E
Sbjct: 61 DIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARSAE 100
>AF321276-1|AAK51704.1| 78|Homo sapiens GTP cyclohydrolase I
protein.
Length = 78
Score = 139 bits (336), Expect = 9e-33
Identities = 64/78 (82%), Positives = 73/78 (93%)
Query: 154 EIFSRRLQVQERLTKQIAIAVTQAVRPAGVAVVIEGVHMCMVMRGVQKINSKTVTSTMLG 213
EI+SRRLQVQERLTKQIA+A+T+A+RPAGV VV+E HMCMVMRGVQK+NSKTVTSTMLG
Sbjct: 1 EIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLG 60
Query: 214 VFRDDPKTREEFLNLVHS 231
VFR+DPKTREEFL L+ S
Sbjct: 61 VFREDPKTREEFLTLIRS 78
>Z30952-1|CAA83213.1| 114|Homo sapiens GTP cyclohydrolase I
protein.
Length = 114
Score = 62.9 bits (146), Expect = 9e-10
Identities = 28/49 (57%), Positives = 38/49 (77%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSL 94
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETI 113
>L29478-1|AAB42186.1| 114|Homo sapiens GTP cyclohydrolase I
protein.
Length = 114
Score = 62.9 bits (146), Expect = 9e-10
Identities = 28/49 (57%), Positives = 38/49 (77%)
Query: 46 EALLPDMANSYRLLLTGLGEDPERAGLLKTPERAAKAMLFFTKGYDQSL 94
E LP++A +Y +L+ LGE+P+R GLLKTP RAA AM FFTKGY +++
Sbjct: 65 ELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETI 113
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 30.7 bits (66), Expect = 4.5
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 11/82 (13%)
Query: 21 FRQVGGHENCTFHHDLELDHRPPTREALLPDMANSYRL------LLTGLGEDPERAGLLK 74
F+ G TFH D E R PT +P AN++ L + + L ++P + L K
Sbjct: 335 FKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHK 394
Query: 75 TPERAAKAML-----FFTKGYD 91
P L FT GY+
Sbjct: 395 VPVHPIVQQLHGNNIHFTDGYE 416
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 30.7 bits (66), Expect = 4.5
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 11/82 (13%)
Query: 21 FRQVGGHENCTFHHDLELDHRPPTREALLPDMANSYRL------LLTGLGEDPERAGLLK 74
F+ G TFH D E R PT +P AN++ L + + L ++P + L K
Sbjct: 335 FKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHK 394
Query: 75 TPERAAKAML-----FFTKGYD 91
P L FT GY+
Sbjct: 395 VPVHPIVQQLHGNNIHFTDGYE 416
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 30.7 bits (66), Expect = 4.5
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 11/82 (13%)
Query: 21 FRQVGGHENCTFHHDLELDHRPPTREALLPDMANSYRL------LLTGLGEDPERAGLLK 74
F+ G TFH D E R PT +P AN++ L + + L ++P + L K
Sbjct: 335 FKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHK 394
Query: 75 TPERAAKAML-----FFTKGYD 91
P L FT GY+
Sbjct: 395 VPVHPIVQQLHGNNIHFTDGYE 416
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 30.7 bits (66), Expect = 4.5
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 11/82 (13%)
Query: 21 FRQVGGHENCTFHHDLELDHRPPTREALLPDMANSYRL------LLTGLGEDPERAGLLK 74
F+ G TFH D E R PT +P AN++ L + + L ++P + L K
Sbjct: 408 FKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHK 467
Query: 75 TPERAAKAML-----FFTKGYD 91
P L FT GY+
Sbjct: 468 VPVHPIVQQLHGNNIHFTDGYE 489
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 30.3 bits (65), Expect = 5.9
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 11/82 (13%)
Query: 21 FRQVGGHENCTFHHDLELDHRPPTREALLPDMANSYRL------LLTGLGEDPERAGLLK 74
F+ G TFH D E R PT +P AN++ L + + L ++P + L K
Sbjct: 335 FKPALGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHK 394
Query: 75 TPERAAKAML-----FFTKGYD 91
P L FT GY+
Sbjct: 395 VPVHPIVQQLHGNNIHFTDGYE 416
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 30.3 bits (65), Expect = 5.9
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 11/82 (13%)
Query: 21 FRQVGGHENCTFHHDLELDHRPPTREALLPDMANSYRL------LLTGLGEDPERAGLLK 74
F+ G TFH D E R PT +P AN++ L + + L ++P + L K
Sbjct: 336 FKPALGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHK 395
Query: 75 TPERAAKAML-----FFTKGYD 91
P L FT GY+
Sbjct: 396 VPVHPIVQQLHGNNIHFTDGYE 417
>BC107585-1|AAI07586.1| 385|Homo sapiens glucose-fructose
oxidoreductase domain containing 2 protein.
Length = 385
Score = 29.9 bits (64), Expect = 7.9
Identities = 26/108 (24%), Positives = 50/108 (46%), Gaps = 4/108 (3%)
Query: 72 LLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYG 131
LL+ +A+ T+ + L E +N A + TD++++ +D+++ +C P
Sbjct: 22 LLRAEGFTVEALWGKTEEEAKQLAEEMNIAFYTSRTDDILLHQDVDL--VCISIPPPLTR 79
Query: 132 KVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVR 179
++S+ L GK + K A V+ F R+ R Q+ V +R
Sbjct: 80 QISVKALGIGKNVVCEKAATSVDAF--RMVTASRYYPQLMSLVGNVLR 125
>AY358169-1|AAQ88536.1| 383|Homo sapiens LPGV9430 protein.
Length = 383
Score = 29.9 bits (64), Expect = 7.9
Identities = 26/108 (24%), Positives = 50/108 (46%), Gaps = 4/108 (3%)
Query: 72 LLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYG 131
LL+ +A+ T+ + L E +N A + TD++++ +D+++ +C P
Sbjct: 20 LLRAEGFTVEALWGKTEEEAKQLAEEMNIAFYTSRTDDILLHQDVDL--VCISIPPPLTR 77
Query: 132 KVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVR 179
++S+ L GK + K A V+ F R+ R Q+ V +R
Sbjct: 78 QISVKALGIGKNVVCEKAATSVDAF--RMVTASRYYPQLMSLVGNVLR 123
>AK074382-1|BAB85066.1| 385|Homo sapiens protein ( Homo sapiens
cDNA FLJ23802 fis, clone HEP22660. ).
Length = 385
Score = 29.9 bits (64), Expect = 7.9
Identities = 26/108 (24%), Positives = 50/108 (46%), Gaps = 4/108 (3%)
Query: 72 LLKTPERAAKAMLFFTKGYDQSLEEVLNNAIFDEDTDEMVVVKDIEMFSMCEHHLVPFYG 131
LL+ +A+ T+ + L E +N A + TD++++ +D+++ +C P
Sbjct: 22 LLRAEGFTVEALWGKTEEEAKQLAEEMNIAFYTSRTDDILLHQDVDL--VCISIPPPLTR 79
Query: 132 KVSIGYLPQGKILGLSKLARIVEIFSRRLQVQERLTKQIAIAVTQAVR 179
++S+ L GK + K A V+ F R+ R Q+ V +R
Sbjct: 80 QISVKALGIGKNVVCEKAATSVDAF--RMVTASRYYPQLMSLVGNVLR 125
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.137 0.399
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 31,575,048
Number of Sequences: 224733
Number of extensions: 1223607
Number of successful extensions: 1803
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1785
Number of HSP's gapped (non-prelim): 27
length of query: 232
length of database: 73,234,838
effective HSP length: 88
effective length of query: 144
effective length of database: 53,458,334
effective search space: 7698000096
effective search space used: 7698000096
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 64 (29.9 bits)
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