Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001205-TA|BGIBMGA001205-PA|IPR002110|Ankyrin,
IPR001660|Sterile alpha motif SAM, IPR010993|Sterile alpha motif
homology
(361 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC126188-1|AAI26189.1| 475|Homo sapiens ankyrin repeat, SAM and... 103 7e-22
BC126186-1|AAI26187.1| 475|Homo sapiens ankyrin repeat, SAM and... 103 7e-22
BC034963-1|AAH34963.1| 393|Homo sapiens ASZ1 protein protein. 103 7e-22
AK093445-1|BAC04167.1| 475|Homo sapiens protein ( Homo sapiens ... 103 7e-22
AF461259-1|AAL68815.1| 475|Homo sapiens GASZ protein. 103 7e-22
BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein pr... 79 3e-14
AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens ... 79 3e-14
AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein. 79 3e-14
BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein. 77 7e-14
AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein. 77 7e-14
BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein. 77 1e-13
AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein pr... 77 1e-13
BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III an... 73 2e-12
AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein. 73 2e-12
AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein. 72 3e-12
BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein. 71 6e-12
BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein. 71 6e-12
BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein. 71 6e-12
AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens ... 71 6e-12
AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein. 71 6e-12
BC117367-1|AAI17368.1| 264|Homo sapiens ankyrin repeat domain 1... 69 3e-11
BC038951-1|AAH38951.1| 264|Homo sapiens ANKRD19 protein protein. 69 3e-11
BC028712-1|AAH28712.1| 264|Homo sapiens ANKRD19 protein protein. 69 3e-11
AL136981-3|CAC12726.1| 264|Homo sapiens ankyrin repeat domain 1... 69 3e-11
X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2... 68 4e-11
X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for ... 68 4e-11
U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein. 68 4e-11
M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein. 68 4e-11
AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4 var... 68 4e-11
AY462872-1|AAS58866.1| 394|Homo sapiens POTE2B protein. 68 6e-11
AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein p... 67 8e-11
AK123496-1|BAC85629.1| 656|Homo sapiens protein ( Homo sapiens ... 67 8e-11
AL139008-2|CAM15100.1| 1011|Homo sapiens ankyrin repeat domain 1... 67 1e-10
AB075857-1|BAB85563.1| 606|Homo sapiens KIAA1977 protein protein. 65 3e-10
BC032799-1|AAH32799.1| 201|Homo sapiens ANKRD7 protein protein. 64 6e-10
BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 2... 64 7e-10
AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein pr... 64 7e-10
AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein. 64 7e-10
AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat... 64 7e-10
AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein. 64 7e-10
AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein. 64 7e-10
X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein. 64 1e-09
BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lys... 64 1e-09
BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lys... 64 1e-09
BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein. 64 1e-09
BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein. 64 1e-09
BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein. 64 1e-09
BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein. 64 1e-09
BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein. 64 1e-09
AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated transc... 64 1e-09
AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated transc... 64 1e-09
AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic histone-ly... 64 1e-09
AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic histone-ly... 64 1e-09
AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic histone-ly... 64 1e-09
AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic histone-ly... 64 1e-09
AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic histone-ly... 64 1e-09
AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic histone-ly... 64 1e-09
AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic histone-ly... 64 1e-09
AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic histone-ly... 64 1e-09
AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens ... 64 1e-09
AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein. 64 1e-09
AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein. 64 1e-09
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 63 1e-09
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 63 1e-09
BC056266-1|AAH56266.1| 357|Homo sapiens ANKRD18A protein protein. 63 1e-09
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 63 1e-09
AL591543-1|CAI17285.1| 992|Homo sapiens ankyrin repeat domain 1... 63 1e-09
AL357148-2|CAI16567.1| 1341|Homo sapiens breast cancer antigen N... 63 1e-09
AL357148-1|CAI16568.1| 1460|Homo sapiens ankyrin repeat domain 3... 63 1e-09
AL157387-4|CAH71319.1| 1460|Homo sapiens ankyrin repeat domain 3... 63 1e-09
AL157387-3|CAH71320.1| 1341|Homo sapiens breast cancer antigen N... 63 1e-09
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 63 1e-09
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 63 1e-09
D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein. 63 2e-09
CR769776-11|CAI95383.1| 823|Homo sapiens ankyrin repeat domain ... 63 2e-09
BX649567-2|CAH71137.1| 823|Homo sapiens ankyrin repeat domain 2... 63 2e-09
BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome, ma... 63 2e-09
AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome, ma... 63 2e-09
AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated transc... 63 2e-09
AB095935-1|BAC23111.1| 996|Homo sapiens KIAA2015 protein protein. 63 2e-09
AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit ... 63 2e-09
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 62 2e-09
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 62 2e-09
CR545463-1|CAM28350.1| 545|Homo sapiens protein expressed in pr... 62 2e-09
BC127623-1|AAI27624.1| 458|Homo sapiens ACTBL1 protein protein. 62 2e-09
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 62 2e-09
AY465172-1|AAS58871.1| 486|Homo sapiens POTE14C protein. 62 2e-09
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 62 2e-09
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 62 2e-09
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 62 2e-09
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 62 2e-09
BX664727-6|CAI39536.1| 823|Homo sapiens ankyrin repeat domain 2... 62 3e-09
AY462874-1|AAS58868.1| 508|Homo sapiens POTE14A protein. 62 3e-09
AY462873-1|AAS58867.1| 376|Homo sapiens POTE2C protein. 62 3e-09
AY462871-1|AAS58865.1| 712|Homo sapiens POTE2A protein. 62 3e-09
AY462868-1|AAS58862.1| 376|Homo sapiens POTE2D protein. 62 3e-09
AL773545-6|CAI12706.1| 823|Homo sapiens ankyrin repeat domain 2... 62 3e-09
AL513478-3|CAH72532.1| 823|Homo sapiens ankyrin repeat domain 2... 62 3e-09
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 62 3e-09
U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein. 62 4e-09
U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein. 62 4e-09
AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1 var... 62 4e-09
D79994-1|BAA11489.2| 1366|Homo sapiens KIAA0172 protein. 61 5e-09
BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome, ma... 61 5e-09
BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH d... 61 5e-09
BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein. 61 5e-09
BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH d... 61 5e-09
BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein. 61 5e-09
BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein. 61 5e-09
BC038116-1|AAH38116.1| 1194|Homo sapiens ankyrin repeat domain 1... 61 5e-09
BC037495-1|AAH37495.1| 1352|Homo sapiens ANKRD15 protein protein. 61 5e-09
BC020040-1|AAH20040.1| 784|Homo sapiens ANKRD15 protein protein. 61 5e-09
BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein. 61 5e-09
BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH d... 61 5e-09
BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH d... 61 5e-09
AL136979-6|CAH70390.1| 276|Homo sapiens ankyrin repeat domain 1... 61 5e-09
AL136979-5|CAH70389.1| 330|Homo sapiens ankyrin repeat domain 1... 61 5e-09
AL136979-4|CAM13084.1| 1194|Homo sapiens ankyrin repeat domain 1... 61 5e-09
AL136979-3|CAH70388.1| 1352|Homo sapiens ankyrin repeat domain 1... 61 5e-09
AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens ... 61 5e-09
AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein. 61 5e-09
AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens ... 61 5e-09
AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeat... 61 5e-09
AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeat... 61 5e-09
AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein. 61 5e-09
AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein. 61 5e-09
EF523384-1|ABP57734.1| 1075|Homo sapiens POTE-2 alpha-actin prot... 61 7e-09
BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH d... 61 7e-09
AF308292-1|AAG48260.1| 352|Homo sapiens serologically defined b... 61 7e-09
AF269087-1|AAK27325.1| 1341|Homo sapiens breast cancer antigen N... 61 7e-09
AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 60 9e-09
AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 60 9e-09
AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 60 9e-09
AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 60 9e-09
AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 60 9e-09
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 60 9e-09
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 60 9e-09
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 60 9e-09
AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS... 60 1e-08
AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens ... 60 1e-08
BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein. 60 2e-08
BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 3... 60 2e-08
BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 3... 60 2e-08
BC066981-1|AAH66981.1| 381|Homo sapiens POTE15 protein protein. 60 2e-08
BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS... 60 2e-08
BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS... 60 2e-08
AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS... 60 2e-08
AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein. 60 2e-08
AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein. 60 2e-08
AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS... 60 2e-08
BC022878-1|AAH22878.1| 776|Homo sapiens ankyrin repeat domain 5... 59 2e-08
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 59 2e-08
AL109754-1|CAB87618.2| 776|Homo sapiens ankyrin repeat domain 5... 59 2e-08
AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK025322-1|BAB15111.1| 416|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK001137-1|BAA91516.1| 546|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 59 2e-08
X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein. 59 3e-08
BC028407-1|AAH28407.1| 619|Homo sapiens ankyrin repeat domain 3... 59 3e-08
BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1... 59 3e-08
AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat do... 59 3e-08
AY172978-1|AAO23914.1| 584|Homo sapiens POTE protein. 59 3e-08
AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1... 59 3e-08
BC127123-1|AAI27124.1| 581|Homo sapiens protein expressed in pr... 58 4e-08
BC101006-1|AAI01007.1| 581|Homo sapiens protein expressed in pr... 58 4e-08
BC101005-1|AAI01006.1| 544|Homo sapiens POTE15 protein protein. 58 4e-08
BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin... 58 4e-08
AY465173-1|AAS58872.1| 581|Homo sapiens POTE15A protein. 58 4e-08
AY465170-1|AAS58869.1| 544|Homo sapiens POTE15B protein. 58 4e-08
BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 58 5e-08
BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 58 5e-08
AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein. 58 5e-08
AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein. 58 5e-08
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 58 6e-08
BC128517-1|AAI28518.1| 309|Homo sapiens ANKRD36 protein protein. 58 6e-08
BC128262-1|AAI28263.1| 346|Homo sapiens ANKRD36 protein protein. 58 6e-08
BC098312-1|AAH98312.1| 851|Homo sapiens ANKRD25 protein protein. 58 6e-08
BC098286-1|AAH98286.1| 851|Homo sapiens ANKRD25 protein protein. 58 6e-08
BC098105-1|AAH98105.1| 851|Homo sapiens ANKRD25 protein protein. 58 6e-08
BC082762-1|AAH82762.1| 851|Homo sapiens ANKRD25 protein protein. 58 6e-08
AY639929-1|AAT57879.1| 859|Homo sapiens SRC-1 interacting prote... 58 6e-08
AK023332-1|BAB14531.1| 454|Homo sapiens protein ( Homo sapiens ... 58 6e-08
AK002094-1|BAA92081.1| 369|Homo sapiens protein ( Homo sapiens ... 58 6e-08
AB040951-1|BAA96042.2| 876|Homo sapiens KIAA1518 protein protein. 58 6e-08
L10381-1|AAA18032.1| 741|Homo sapiens 2-5A-dependent RNase prot... 57 8e-08
DQ309791-1|ABC48694.1| 871|Homo sapiens SamCystin protein. 57 8e-08
BC115697-1|AAI15698.1| 741|Homo sapiens ribonuclease L (2',5'-o... 57 8e-08
BC114433-1|AAI14434.1| 741|Homo sapiens ribonuclease L protein. 57 8e-08
BC090934-1|AAH90934.1| 652|Homo sapiens RNASEL protein protein. 57 8e-08
AL807776-3|CAM13062.1| 871|Homo sapiens ankyrin repeat and ster... 57 8e-08
AL807776-2|CAH69986.2| 584|Homo sapiens ankyrin repeat and ster... 57 8e-08
AL353782-4|CAM14169.1| 871|Homo sapiens ankyrin repeat and ster... 57 8e-08
AL353782-3|CAH71296.2| 584|Homo sapiens ankyrin repeat and ster... 57 8e-08
AL138776-1|CAH71322.1| 741|Homo sapiens ribonuclease L (2',5'-o... 57 8e-08
AL031177-4|CAI43134.1| 193|Homo sapiens proteasome (prosome, ma... 57 8e-08
AC007874-1|AAF19231.1| 131|Homo sapiens WUGSC:H_DJ1035O02.1 pro... 57 8e-08
AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein pr... 57 1e-07
AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens ... 57 1e-07
AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens ... 57 1e-07
AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein pr... 57 1e-07
BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein. 56 1e-07
BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein. 56 1e-07
BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein. 56 1e-07
BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein. 56 1e-07
BC071771-1|AAH71771.1| 239|Homo sapiens KIAA1641 protein protein. 56 1e-07
BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein. 56 1e-07
BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein. 56 1e-07
BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein. 56 1e-07
AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined b... 56 1e-07
AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein. 56 1e-07
Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein. 56 2e-07
X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein. 56 2e-07
BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein pr... 56 2e-07
AK074570-1|BAC11066.1| 239|Homo sapiens protein ( Homo sapiens ... 56 2e-07
D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein. 56 3e-07
BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and ster... 56 3e-07
BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for IM... 56 3e-07
AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and ster... 56 3e-07
AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and ster... 56 3e-07
AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and ster... 56 3e-07
BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a pro... 55 4e-07
BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 2... 55 4e-07
AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat p... 55 4e-07
AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase, TRF1-interac... 55 4e-07
AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containi... 55 4e-07
AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyri... 55 4e-07
AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein. 55 4e-07
AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein. 55 4e-07
AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein. 55 4e-07
AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein. 55 4e-07
AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related prote... 55 4e-07
AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein ... 55 4e-07
AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein. 55 4e-07
U13048-1|AAA65710.1| 348|Homo sapiens nuclear respiratory facto... 54 6e-07
U13047-1|AAA65709.1| 360|Homo sapiens nuclear respiratory facto... 54 6e-07
U13046-1|AAA65708.1| 383|Homo sapiens nuclear respiratory facto... 54 6e-07
U13045-1|AAA65707.1| 395|Homo sapiens nuclear respiratory facto... 54 6e-07
D13317-1|BAA02574.1| 383|Homo sapiens transcription factor E4TF... 54 6e-07
D13316-1|BAA02573.1| 347|Homo sapiens transcription factor E4TF... 54 6e-07
BT006652-1|AAP35298.1| 360|Homo sapiens GA binding protein tran... 54 6e-07
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 54 6e-07
BC050702-1|AAH50702.1| 395|Homo sapiens GA binding protein tran... 54 6e-07
BC046186-1|AAH46186.1| 163|Homo sapiens ankyrin repeat domain 3... 54 6e-07
BC036080-1|AAH36080.1| 383|Homo sapiens GA binding protein tran... 54 6e-07
BC016910-1|AAH16910.1| 360|Homo sapiens GA binding protein tran... 54 6e-07
AY462869-1|AAS58863.1| 498|Homo sapiens POTE8A protein. 54 6e-07
AY358571-1|AAQ88934.1| 151|Homo sapiens ankyrin-related protein. 54 6e-07
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 54 6e-07
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 54 6e-07
AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens ... 54 6e-07
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 54 6e-07
AC018892-2|AAY14642.1| 163|Homo sapiens unknown protein. 54 6e-07
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 54 6e-07
BC101007-1|AAI01008.1| 301|Homo sapiens POTE15 protein protein. 54 8e-07
BC004988-1|AAH04988.1| 669|Homo sapiens fem-1 homolog a (C. ele... 54 8e-07
AY356352-1|AAR10439.1| 669|Homo sapiens prostaglandin E recepto... 54 8e-07
AL158217-11|CAI22163.1| 854|Homo sapiens espin protein. 54 8e-07
AL031848-3|CAI19773.1| 854|Homo sapiens espin protein. 54 8e-07
AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens ... 54 8e-07
AJ311359-1|CAC85342.1| 668|Homo sapiens putative sex determinin... 54 8e-07
Y10601-1|CAA71610.1| 1119|Homo sapiens ankyrin-like protein prot... 53 1e-06
BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein. 53 1e-06
BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin pro... 53 1e-06
BC012917-1|AAH12917.1| 313|Homo sapiens ankyrin repeat, family ... 53 1e-06
AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein. 53 1e-06
AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein. 53 1e-06
AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein. 53 1e-06
AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein. 53 1e-06
AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein. 53 1e-06
AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein. 53 1e-06
AK023214-1|BAB14467.1| 677|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AK022876-1|BAB14288.1| 313|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AF314032-1|AAK01621.1| 313|Homo sapiens ankyrin-repeat family A... 53 1e-06
AF251051-1|AAK34941.1| 313|Homo sapiens ankyrin protein. 53 1e-06
AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein altern... 53 1e-06
AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein. 53 1e-06
AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein. 53 1e-06
AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog p... 53 1e-06
BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS... 53 2e-06
BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein. 53 2e-06
AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone met... 53 2e-06
AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lys... 53 2e-06
AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lys... 53 2e-06
AL035288-1|CAA22892.1| 671|Homo sapiens hypothetical protein pr... 53 2e-06
AL021920-3|CAI19632.1| 671|Homo sapiens espin pseudogene protein. 53 2e-06
AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein pr... 53 2e-06
AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein. 53 2e-06
AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteini... 53 2e-06
AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein. 53 2e-06
AK125360-1|BAC86146.1| 588|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AK098736-1|BAC05399.1| 181|Homo sapiens protein ( Homo sapiens ... 52 3e-06
BC100877-1|AAI00878.1| 241|Homo sapiens ASB15 protein protein. 52 4e-06
BC100876-1|AAI00877.1| 241|Homo sapiens ASB15 protein protein. 52 4e-06
BC100875-1|AAI00876.1| 241|Homo sapiens ASB15 protein protein. 52 4e-06
BC100874-1|AAI00875.1| 241|Homo sapiens ASB15 protein protein. 52 4e-06
BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase, TRF1-interac... 52 4e-06
AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting ankyri... 52 4e-06
D78334-1|BAA11348.1| 151|Homo sapiens ankyrin motif protein. 51 6e-06
BC127726-1|AAI27727.1| 165|Homo sapiens MGC26718 protein protein. 51 6e-06
BC022023-1|AAH22023.1| 117|Homo sapiens similar to ankyrin repe... 51 6e-06
BC007020-1|AAH07020.2| 156|Homo sapiens ANKRD7 protein protein. 51 6e-06
AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6... 51 6e-06
AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6... 51 6e-06
AB024494-1|BAC22089.1| 633|Homo sapiens huntingtin interacting ... 51 6e-06
U40282-1|AAC16892.1| 452|Homo sapiens integrin-linked kinase pr... 51 7e-06
CR407673-1|CAG28601.1| 452|Homo sapiens ILK protein. 51 7e-06
BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6... 51 7e-06
BC028369-1|AAH28369.1| 617|Homo sapiens fem-1 homolog c (C. ele... 51 7e-06
BC001554-1|AAH01554.1| 452|Homo sapiens integrin-linked kinase ... 51 7e-06
AY249188-1|AAO64429.1| 617|Homo sapiens FEM1C protein. 51 7e-06
AL365415-1|CAB96957.1| 271|Homo sapiens similar to (NP_034322.1... 51 7e-06
AJ404847-1|CAB99253.1| 452|Homo sapiens integrin-linked kinase ... 51 7e-06
AJ277481-1|CAB94832.1| 452|Homo sapiens integrin-linked kinase-... 51 7e-06
AF391093-1|AAL37627.1| 617|Homo sapiens FEM1A protein. 51 7e-06
AF244139-1|AAF74449.1| 452|Homo sapiens integrin-linked kinase ... 51 7e-06
AB058688-1|BAB47414.1| 617|Homo sapiens KIAA1785 protein protein. 51 7e-06
AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein. 51 7e-06
BC050324-1|AAH50324.1| 632|Homo sapiens zinc finger, DHHC-type ... 50 1e-05
AK092564-1|BAC03915.1| 263|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AB097035-1|BAC77388.1| 622|Homo sapiens putative MAPK activatin... 50 1e-05
AB097013-1|BAC77366.1| 622|Homo sapiens putative NFkB activatin... 50 1e-05
AB023163-1|BAA76790.1| 667|Homo sapiens KIAA0946 protein protein. 50 1e-05
DQ388145-2|ABD72216.1| 1482|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388144-2|ABD72214.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388143-2|ABD72212.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388142-2|ABD72210.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388141-2|ABD72208.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388140-2|ABD72206.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388139-2|ABD72204.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388138-2|ABD72202.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388137-2|ABD72200.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388136-2|ABD72198.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388135-2|ABD72196.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388134-2|ABD72194.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388133-2|ABD72192.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388132-2|ABD72190.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388131-2|ABD72188.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388130-2|ABD72186.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388129-2|ABD72184.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ388128-2|ABD72182.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ356264-2|ABC87066.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ356263-2|ABC87064.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ356262-2|ABC87062.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ356261-2|ABC87060.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ356260-2|ABC87058.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ356259-2|ABC87056.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ356258-2|ABC87054.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ356257-2|ABC87052.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ354391-2|ABC79055.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ354390-2|ABC79053.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ354389-2|ABC79051.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
DQ354388-2|ABC79049.1| 1663|Homo sapiens CTTNBP2 protein. 50 1e-05
BC106000-1|AAI06001.1| 1663|Homo sapiens cortactin binding prote... 50 1e-05
AF377960-1|AAL32176.1| 1663|Homo sapiens cortactin-binding prote... 50 1e-05
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 50 1e-05
AB051545-1|BAB21849.1| 1662|Homo sapiens KIAA1758 protein protein. 50 1e-05
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 50 2e-05
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 50 2e-05
BC037542-1|AAH37542.1| 999|Homo sapiens MIB2 protein protein. 50 2e-05
BC030990-1|AAH30990.1| 276|Homo sapiens ZDHHC17 protein protein. 50 2e-05
BC016881-1|AAH16881.1| 638|Homo sapiens Unknown (protein for IM... 50 2e-05
BC016490-1|AAH16490.1| 1030|Homo sapiens MIB2 protein protein. 50 2e-05
AL691432-4|CAM12833.1| 919|Homo sapiens mindbomb homolog 2 (Dro... 50 2e-05
AL691432-3|CAM12832.1| 753|Homo sapiens mindbomb homolog 2 (Dro... 50 2e-05
AL691432-2|CAM12831.1| 999|Homo sapiens mindbomb homolog 2 (Dro... 50 2e-05
AL691432-1|CAM12830.1| 948|Homo sapiens mindbomb homolog 2 (Dro... 50 2e-05
AK098785-1|BAC05413.1| 802|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AK097106-1|BAC04952.1| 819|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AK095914-1|BAC04646.1| 681|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AK091610-1|BAC03707.1| 645|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AK055435-1|BAB70922.1| 634|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AB097000-1|BAC77353.1| 999|Homo sapiens putative NFkB activatin... 50 2e-05
AB076693-1|BAC00994.1| 1009|Homo sapiens skeletrophin gamma prot... 50 2e-05
AB076692-1|BAC00993.1| 948|Homo sapiens skeletrophin beta protein. 50 2e-05
AB076691-1|BAC00992.1| 999|Homo sapiens skeletrophin alpha prot... 50 2e-05
AB074480-1|BAB92950.1| 1013|Homo sapiens skeletrophin protein. 50 2e-05
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 50 2e-05
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 49 2e-05
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 49 2e-05
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 49 2e-05
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 49 2e-05
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 49 2e-05
BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 1... 49 2e-05
AY462870-1|AAS58864.1| 452|Homo sapiens POTE8B protein. 49 2e-05
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 49 2e-05
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 49 2e-05
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 49 2e-05
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 49 2e-05
AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 1... 49 2e-05
AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting ankyri... 49 2e-05
CR457336-1|CAG33617.1| 288|Homo sapiens ASB8 protein. 49 3e-05
BC001321-1|AAH01321.1| 288|Homo sapiens ankyrin repeat and SOCS... 49 3e-05
AY465171-1|AAS58870.1| 594|Homo sapiens POTE14B protein. 49 3e-05
AY057056-1|AAL25260.1| 151|Homo sapiens hepatocellular carcinom... 49 3e-05
AL031177-6|CAI43131.1| 151|Homo sapiens proteasome (prosome, ma... 49 3e-05
AK024908-1|BAB15033.1| 288|Homo sapiens NP3) mRNA. protein. 49 3e-05
AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin... 48 4e-05
AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin... 48 4e-05
AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin... 48 4e-05
AK096295-1|BAC04752.1| 681|Homo sapiens protein ( Homo sapiens ... 48 4e-05
D87930-1|BAA22378.1| 1030|Homo sapiens myosin phosphatase target... 48 5e-05
BC111752-1|AAI11753.1| 1030|Homo sapiens PPP1R12A protein protein. 48 5e-05
BC092481-1|AAH92481.1| 730|Homo sapiens PPP1R12A protein protein. 48 5e-05
BC047898-1|AAH47898.1| 692|Homo sapiens PPP1R12A protein protein. 48 5e-05
BC006404-1|AAH06404.1| 707|Homo sapiens ClpB caseinolytic pepti... 48 5e-05
BC003542-1|AAH03542.2| 860|Homo sapiens M-phase phosphoprotein,... 48 5e-05
AY380574-1|AAQ88438.1| 974|Homo sapiens myosin phosphatase targ... 48 5e-05
AL359457-4|CAI16671.1| 860|Homo sapiens M-phase phosphoprotein,... 48 5e-05
AL354808-3|CAI41002.1| 860|Homo sapiens M-phase phosphoprotein,... 48 5e-05
AK075298-1|BAC11532.1| 129|Homo sapiens protein ( Homo sapiens ... 48 5e-05
AK000904-1|BAA91417.1| 519|Homo sapiens protein ( Homo sapiens ... 48 5e-05
AF458589-1|AAM49717.1| 995|Homo sapiens myosin phosphatase targ... 48 5e-05
AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containi... 48 5e-05
AB033081-1|BAA86569.2| 1232|Homo sapiens KIAA1255 protein protein. 48 5e-05
BC063581-1|AAH63581.1| 274|Homo sapiens ankyrin repeat and SOCS... 48 7e-05
AK222974-1|BAD96694.1| 274|Homo sapiens ankyrin repeat and SOCS... 48 7e-05
AK222958-1|BAD96678.1| 274|Homo sapiens ankyrin repeat and SOCS... 48 7e-05
AK026204-1|BAB15392.1| 274|Homo sapiens protein ( Homo sapiens ... 48 7e-05
AF451994-1|AAP97683.1| 318|Homo sapiens ankyrin repeat-containi... 48 7e-05
U76638-1|AAB38316.1| 777|Homo sapiens BRCA1-associated RING dom... 47 9e-05
BC126426-1|AAI26427.1| 777|Homo sapiens BRCA1 associated RING d... 47 9e-05
BC070234-1|AAH70234.1| 371|Homo sapiens ANKRD12 protein protein. 47 9e-05
BC057225-1|AAH57225.1| 330|Homo sapiens ANKRD12 protein protein. 47 9e-05
AY533564-1|AAS45545.2| 2039|Homo sapiens ankyrin repeat-containi... 47 9e-05
AY373757-1|AAR25662.1| 2062|Homo sapiens ankyrin repeat-containi... 47 9e-05
AK223409-1|BAD97129.1| 777|Homo sapiens BRCA1 associated RING d... 47 9e-05
AK057782-1|BAB71569.1| 268|Homo sapiens protein ( Homo sapiens ... 47 9e-05
AK057011-1|BAB71342.1| 258|Homo sapiens protein ( Homo sapiens ... 47 9e-05
AK024808-1|BAB15014.1| 492|Homo sapiens protein ( Homo sapiens ... 47 9e-05
AF317425-1|AAG38609.1| 2062|Homo sapiens GAC-1 protein. 47 9e-05
AF038042-1|AAB99978.1| 777|Homo sapiens BRCA1-associated RING d... 47 9e-05
AC016708-1|AAX93130.1| 777|Homo sapiens unknown protein. 47 9e-05
BX005460-4|CAM26150.1| 297|Homo sapiens euchromatic histone-lys... 47 1e-04
BC126428-1|AAI26429.1| 777|Homo sapiens BRCA1 associated RING d... 47 1e-04
BC113481-1|AAI13482.1| 349|Homo sapiens ankyrin repeat and SOCS... 47 1e-04
BC113479-1|AAI13480.1| 349|Homo sapiens ankyrin repeat and SOCS... 47 1e-04
BC107759-1|AAI07760.1| 360|Homo sapiens ankyrin repeat domain 2... 47 1e-04
BC041099-1|AAH41099.1| 462|Homo sapiens nudix (nucleoside dipho... 47 1e-04
BC025024-1|AAH25024.1| 318|Homo sapiens Unknown (protein for IM... 47 1e-04
BC020817-1|AAH20817.2| 303|Homo sapiens ANKRD2 protein protein. 47 1e-04
AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein. 47 1e-04
AL671762-12|CAI18225.2| 297|Homo sapiens euchromatic histone-ly... 47 1e-04
AL662834-23|CAM24991.1| 297|Homo sapiens euchromatic histone-ly... 47 1e-04
AL359388-5|CAI14193.1| 300|Homo sapiens ankyrin repeat domain 2... 47 1e-04
AL359388-4|CAI14194.1| 333|Homo sapiens ankyrin repeat domain 2... 47 1e-04
AL355315-10|CAI15462.1| 300|Homo sapiens ankyrin repeat domain ... 47 1e-04
AL355315-9|CAI15463.1| 333|Homo sapiens ankyrin repeat domain 2... 47 1e-04
AK131450-1|BAD18595.1| 1340|Homo sapiens protein ( Homo sapiens ... 47 1e-04
AJ583444-1|CAE47432.1| 449|Homo sapiens ankyrin repeat protein ... 47 1e-04
AJ304805-1|CAC19412.1| 333|Homo sapiens skeletal muscle ankyrin... 47 1e-04
AJ304804-1|CAC19411.1| 333|Homo sapiens skeletal muscle ankyrin... 47 1e-04
AF156779-1|AAD41896.1| 426|Homo sapiens ASB-4 protein protein. 47 1e-04
AC003079-1|AAB83943.2| 426|Homo sapiens unknown protein. 47 1e-04
AB058599-1|BAB60958.1| 333|Homo sapiens ankyrin-repeat protein ... 47 1e-04
CR457302-1|CAG33583.1| 278|Homo sapiens ASB13 protein. 46 2e-04
BC105989-1|AAI05990.1| 112|Homo sapiens ANKRD25 protein protein. 46 2e-04
BC070117-1|AAH70117.1| 321|Homo sapiens FLJ43980 protein protein. 46 2e-04
AL365356-2|CAH72614.1| 278|Homo sapiens ankyrin repeat and SOCS... 46 2e-04
CR542199-1|CAG46996.1| 260|Homo sapiens RFXANK protein. 46 2e-04
CR456981-1|CAG33262.1| 260|Homo sapiens RFXANK protein. 46 2e-04
BC114563-1|AAI14564.1| 260|Homo sapiens regulatory factor X-ass... 46 2e-04
BC114558-1|AAI14559.1| 238|Homo sapiens regulatory factor X-ass... 46 2e-04
BC056152-1|AAH56152.1| 622|Homo sapiens zinc finger, DHHC-type ... 46 2e-04
BC036020-1|AAH36020.1| 622|Homo sapiens zinc finger, DHHC-type ... 46 2e-04
BC035353-1|AAH35353.1| 441|Homo sapiens ankyrin repeat and MYND... 46 2e-04
AK001714-1|BAA91856.1| 481|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AF403031-1|AAL57350.1| 286|Homo sapiens ankyrin repeat domain-c... 46 2e-04
AF105428-1|AAD17973.1| 237|Homo sapiens putative protein RFX-Bd... 46 2e-04
AF105427-1|AAD17972.1| 260|Homo sapiens transcription factor RF... 46 2e-04
AF094760-1|AAC69883.1| 260|Homo sapiens RFXANK protein. 46 2e-04
AC003110-1|AAB86654.1| 196|Homo sapiens F14150_1 protein. 46 2e-04
AB097027-1|BAC77380.1| 622|Homo sapiens putative MAPK activatin... 46 2e-04
AB097014-1|BAC77367.1| 622|Homo sapiens putative NFkB activatin... 46 2e-04
AB024495-1|BAC22090.1| 622|Homo sapiens huntingtin interacting ... 46 2e-04
M69043-1|AAA16489.1| 317|Homo sapiens MAD3 protein. 45 4e-04
BT007091-1|AAP35754.1| 317|Homo sapiens nuclear factor of kappa... 45 4e-04
BC004983-1|AAH04983.1| 317|Homo sapiens nuclear factor of kappa... 45 4e-04
BC002601-1|AAH02601.1| 317|Homo sapiens nuclear factor of kappa... 45 4e-04
AY496422-1|AAR29599.1| 317|Homo sapiens nuclear factor of kappa... 45 4e-04
AY033600-1|AAK51149.1| 317|Homo sapiens NFKBIA protein. 45 4e-04
AJ318887-1|CAC83011.2| 1090|Homo sapiens ASPP1 protein protein. 45 4e-04
AJ249294-1|CAB65556.2| 317|Homo sapiens IkBa protein. 45 4e-04
AB018314-1|BAA34491.1| 948|Homo sapiens KIAA0771 protein protein. 45 4e-04
BC027033-1|AAH27033.1| 448|Homo sapiens hypothetical protein MG... 45 5e-04
AL691467-2|CAH73760.1| 410|Homo sapiens novel protein protein. 45 5e-04
AL691467-1|CAH73759.1| 448|Homo sapiens novel protein protein. 45 5e-04
AL592424-19|CAI16391.1| 410|Homo sapiens novel protein protein. 45 5e-04
AL592424-18|CAI16392.1| 448|Homo sapiens novel protein protein. 45 5e-04
AL590133-27|CAI13351.1| 448|Homo sapiens novel protein protein. 45 5e-04
AL590133-26|CAI13352.1| 410|Homo sapiens novel protein protein. 45 5e-04
AL133548-4|CAH71573.1| 214|Homo sapiens osteoclast stimulating ... 45 5e-04
AK222596-1|BAD96316.1| 214|Homo sapiens osteoclast stimulating ... 45 5e-04
AK023196-1|BAB14456.1| 278|Homo sapiens ARPP-19) mRNA. protein. 44 6e-04
AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase, TRF1-interac... 44 6e-04
U63717-1|AAB06396.1| 214|Homo sapiens osteoclast stimulating fa... 44 8e-04
BX537853-1|CAD97861.1| 302|Homo sapiens hypothetical protein pr... 44 8e-04
BC103875-1|AAI03876.1| 323|Homo sapiens ankyrin repeat and SOCS... 44 8e-04
BC103874-1|AAI03875.1| 323|Homo sapiens ankyrin repeat and SOCS... 44 8e-04
BC069340-1|AAH69340.1| 323|Homo sapiens ankyrin repeat and SOCS... 44 8e-04
>BC126188-1|AAI26189.1| 475|Homo sapiens ankyrin repeat, SAM and
basic leucine zipper domain containing 1 protein.
Length = 475
Score = 103 bits (248), Expect = 7e-22
Identities = 78/308 (25%), Positives = 146/308 (47%), Gaps = 9/308 (2%)
Query: 10 SDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNA 69
S+ + D + G+ ++ + I KK+ ++A+ G++ V++L+++ + ++
Sbjct: 18 SESEDDGWEIGYLDRTSQKLKRLLPIEEKKE---KFKKAMTIGDVSLVQELLDSGISVDS 74
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSI 129
N + GWTPLM+A A ++V+ LL++ A+ + D + ++ ACS ++ + I
Sbjct: 75 NFQY--GWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSE-EQILKC 131
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
V L+ RN N+ R TP+M A G V L+ + +D++G+TA+ WA
Sbjct: 132 VELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAAR 191
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN-LDDD-HKTDEN 247
I+ L+E GA K + EIA + H I +L +LN L+ + +
Sbjct: 192 QGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLLSFTLNPLEGKLQQLTKE 251
Query: 248 SYLNHQLTSWQDYYPGIEKNERPNYKNEIQNLLYGMSCERLTPLIVTSGIDLRTFLLLDA 307
+ LT+ D + + +++ L+G+ E +T L+ I LR L +
Sbjct: 252 DTICKILTTDSDREKDHIFSSYTAF-GDLEVFLHGLGLEHMTDLLKERDITLRHLLTMRE 310
Query: 308 EEMVKLGI 315
+E K GI
Sbjct: 311 DEFTKNGI 318
>BC126186-1|AAI26187.1| 475|Homo sapiens ankyrin repeat, SAM and
basic leucine zipper domain containing 1 protein.
Length = 475
Score = 103 bits (248), Expect = 7e-22
Identities = 78/308 (25%), Positives = 146/308 (47%), Gaps = 9/308 (2%)
Query: 10 SDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNA 69
S+ + D + G+ ++ + I KK+ ++A+ G++ V++L+++ + ++
Sbjct: 18 SESEDDGWEIGYLDRTSQKLKRLLPIEEKKE---KFKKAMTIGDVSLVQELLDSGISVDS 74
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSI 129
N + GWTPLM+A A ++V+ LL++ A+ + D + ++ ACS ++ + I
Sbjct: 75 NFQY--GWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSE-EQILKC 131
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
V L+ RN N+ R TP+M A G V L+ + +D++G+TA+ WA
Sbjct: 132 VELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAAR 191
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN-LDDD-HKTDEN 247
I+ L+E GA K + EIA + H I +L +LN L+ + +
Sbjct: 192 QGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLLSFTLNPLEGKLQQLTKE 251
Query: 248 SYLNHQLTSWQDYYPGIEKNERPNYKNEIQNLLYGMSCERLTPLIVTSGIDLRTFLLLDA 307
+ LT+ D + + +++ L+G+ E +T L+ I LR L +
Sbjct: 252 DTICKILTTDSDREKDHIFSSYTAF-GDLEVFLHGLGLEHMTDLLKERDITLRHLLTMRE 310
Query: 308 EEMVKLGI 315
+E K GI
Sbjct: 311 DEFTKNGI 318
>BC034963-1|AAH34963.1| 393|Homo sapiens ASZ1 protein protein.
Length = 393
Score = 103 bits (248), Expect = 7e-22
Identities = 78/308 (25%), Positives = 146/308 (47%), Gaps = 9/308 (2%)
Query: 10 SDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNA 69
S+ + D + G+ ++ + I KK+ ++A+ G++ V++L+++ + ++
Sbjct: 18 SESEDDGWEIGYLDRTSQKLKRLLPIEEKKE---KFKKAMTIGDVSLVQELLDSGISVDS 74
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSI 129
N + GWTPLM+A A ++V+ LL++ A+ + D + ++ ACS ++ + I
Sbjct: 75 NFQY--GWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSE-EQILKC 131
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
V L+ RN N+ R TP+M A G V L+ + +D++G+TA+ WA
Sbjct: 132 VELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAAR 191
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN-LDDD-HKTDEN 247
I+ L+E GA K + EIA + H I +L +LN L+ + +
Sbjct: 192 QGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLLSFTLNPLEGKLQQLTKE 251
Query: 248 SYLNHQLTSWQDYYPGIEKNERPNYKNEIQNLLYGMSCERLTPLIVTSGIDLRTFLLLDA 307
+ LT+ D + + +++ L+G+ E +T L+ I LR L +
Sbjct: 252 DTICKILTTDSDREKDHIFSSYTAF-GDLEVFLHGLGLEHMTDLLKERDITLRHLLTMRE 310
Query: 308 EEMVKLGI 315
+E K GI
Sbjct: 311 DEFTKNGI 318
>AK093445-1|BAC04167.1| 475|Homo sapiens protein ( Homo sapiens
cDNA FLJ36126 fis, clone TESTI2024443, weakly similar to
ANKYRIN 1. ).
Length = 475
Score = 103 bits (248), Expect = 7e-22
Identities = 78/308 (25%), Positives = 146/308 (47%), Gaps = 9/308 (2%)
Query: 10 SDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNA 69
S+ + D + G+ ++ + I KK+ ++A+ G++ V++L+++ + ++
Sbjct: 18 SESEDDGWEIGYLDRTSQKLKRLLPIEEKKE---KFKKAMTIGDVSLVQELLDSGISVDS 74
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSI 129
N + GWTPLM+A A ++V+ LL++ A+ + D + ++ ACS ++ + I
Sbjct: 75 NFQY--GWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSE-EQILKC 131
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
V L+ RN N+ R TP+M A G V L+ + +D++G+TA+ WA
Sbjct: 132 VELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAAR 191
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN-LDDD-HKTDEN 247
I+ L+E GA K + EIA + H I +L +LN L+ + +
Sbjct: 192 QGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLLSFTLNPLEGKLQQLTKE 251
Query: 248 SYLNHQLTSWQDYYPGIEKNERPNYKNEIQNLLYGMSCERLTPLIVTSGIDLRTFLLLDA 307
+ LT+ D + + +++ L+G+ E +T L+ I LR L +
Sbjct: 252 DTICKILTTDSDREKDHIFSSYTAF-GDLEVFLHGLGLEHMTDLLKERDITLRHLLTMRE 310
Query: 308 EEMVKLGI 315
+E K GI
Sbjct: 311 DEFTKNGI 318
>AF461259-1|AAL68815.1| 475|Homo sapiens GASZ protein.
Length = 475
Score = 103 bits (248), Expect = 7e-22
Identities = 78/308 (25%), Positives = 146/308 (47%), Gaps = 9/308 (2%)
Query: 10 SDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNA 69
S+ + D + G+ ++ + I KK+ ++A+ G++ V++L+++ + ++
Sbjct: 18 SESEDDGWEIGYLDRTSQKLKRLLPIEEKKE---KFKKAMTIGDVSLVQELLDSGISVDS 74
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSI 129
N + GWTPLM+A A ++V+ LL++ A+ + D + ++ ACS ++ + I
Sbjct: 75 NFQY--GWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSE-EQILKC 131
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
V L+ RN N+ R TP+M A G V L+ + +D++G+TA+ WA
Sbjct: 132 VELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAAR 191
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN-LDDD-HKTDEN 247
I+ L+E GA K + EIA + H I +L +LN L+ + +
Sbjct: 192 QGHKNIVLKLLELGANKMLQTKDGKMPSEIAKRNKHHEIFNLLSFTLNPLEGKLQQLTKE 251
Query: 248 SYLNHQLTSWQDYYPGIEKNERPNYKNEIQNLLYGMSCERLTPLIVTSGIDLRTFLLLDA 307
+ LT+ D + + +++ L+G+ E +T L+ I LR L +
Sbjct: 252 DTICKILTTDSDREKDHIFSSYTAF-GDLEVFLHGLGLEHMTDLLKERDITLRHLLTMRE 310
Query: 308 EEMVKLGI 315
+E K GI
Sbjct: 311 DEFTKNGI 318
>BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein
protein.
Length = 1280
Score = 78.6 bits (185), Expect = 3e-14
Identities = 56/194 (28%), Positives = 99/194 (51%), Gaps = 11/194 (5%)
Query: 58 EDLINNELKNNANI-KLDS-GWTPLMHACFHAQDKIVQYLLEKDADPNLHSD----SVTP 111
ED++ N L++ A + K D+ G T L+ A + +IV++LL+ A+ N H D +
Sbjct: 508 EDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVN-HEDVDGRTALS 566
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ A C +S + ++ S+ LIDR ++ D+ G TPL+ A G V V LL+
Sbjct: 567 VAALCVPASKGHASVVSL---LIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGA 623
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
+++ D +G T + A ++ L+ GA + +D RT+L IA+ + ++
Sbjct: 624 DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRT 683
Query: 232 LKKSLNLDDDHKTD 245
L LD++H+ D
Sbjct: 684 L-LDRGLDENHRDD 696
Score = 76.6 bits (180), Expect = 1e-13
Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 10/167 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ A + +V LLE AD + H+D+ TP++AA S A S+V L
Sbjct: 599 GMTPLLVAAYEGHVDVVDLLLEGGADVD-HTDNNGRTPLLAAASMGHA------SVVNTL 651
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ ++ D G+T L A + G V V + LLD ++ RD GWT + A
Sbjct: 652 LFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHR 711
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLD 239
I E LIE+GAR E+D R +A+ H ++I L+ N+D
Sbjct: 712 LICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNID 758
Score = 58.8 bits (136), Expect = 3e-08
Identities = 46/189 (24%), Positives = 79/189 (41%), Gaps = 9/189 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A GN++ V L++ L N + D+GWTPL A F I + L+E+ A N
Sbjct: 669 LSIASAQGNVEVVRTLLDRGLDENH--RDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 726
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ +D P + A Y V L++ ++ G+ L A G +
Sbjct: 727 IDNDGRIPFILASQEGH------YDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIV 780
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ L ++ +D G ++ NQ + E +E GA + D RT L ++
Sbjct: 781 ELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQ 840
Query: 224 DHQVIIEIL 232
H ++++L
Sbjct: 841 GHMEMVQVL 849
Score = 58.0 bits (134), Expect = 5e-08
Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 7/173 (4%)
Query: 58 EDLINNELKNNANIKLDSGWTP-LMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
++++ +K A++ + T ++ +D I + LL+ A N + ++A
Sbjct: 345 QEVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSI-RTLLDNGASVNQCDSNGRTLLANA 403
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ S + +V L+ R L I D +G TPL A G V L+ NI
Sbjct: 404 AYSGS-----LDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHT 458
Query: 177 DQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVII 229
DQ GWTA+ A E++ L+ G ++ D +RT L A H+ I+
Sbjct: 459 DQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIV 511
Score = 49.2 bits (112), Expect = 2e-05
Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 13/179 (7%)
Query: 60 LINNELK-NNANIKLDSGW--TPL---MHACFHAQDKIVQYLLEKDADPNLHSDSVTPIM 113
LIN+ L+ A + L W TP+ + + +++Q L++ A N D + I+
Sbjct: 310 LINSNLQLETAELALWMIWNGTPVRDSLSTLIPKEQEVLQLLVKAGAHVNSEDDRTSCIV 369
Query: 114 AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNI 173
D+I + L+D +N D G+T L A SG + V L+ ++
Sbjct: 370 RQALERE---DSIRT----LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADL 422
Query: 174 EMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E+ D HG T + A +++ LI GA + D+ T L A H ++ L
Sbjct: 423 EIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSAL 481
Score = 45.2 bits (102), Expect = 4e-04
Identities = 45/171 (26%), Positives = 73/171 (42%), Gaps = 11/171 (6%)
Query: 73 LDS-GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIV 130
+DS G T L A ++V+ LL++ D N D+ TP+ A + ++
Sbjct: 661 IDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEG-------HRLI 713
Query: 131 CN-LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
C LI++ N D G+ P + A G Q LL+ + NI+ R G A+ A
Sbjct: 714 CEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAAL 773
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIE-ILKKSLNLD 239
+I+E+L GA + D R L I + + E L+ N++
Sbjct: 774 EGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVE 824
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/177 (22%), Positives = 75/177 (42%), Gaps = 9/177 (5%)
Query: 59 DLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDAD-PNLHSDSVTPIMAA 115
D+++ L+ A++ ++G TPL+ A +V LL A ++ S+ T + A
Sbjct: 613 DVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIA 672
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + + +V L+DR N D G TPL A G + + L++
Sbjct: 673 SAQGNVE------VVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 726
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
D G A + +++L+E + + + R L +A H+ I+E+L
Sbjct: 727 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELL 783
Score = 30.7 bits (66), Expect = 8.3
Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
ALQ A G++K V+ LI + + + G T L A +VQ LLE ADPN
Sbjct: 866 ALQSAAWQGHVKVVQLLIEHGAV--VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPN 923
Query: 104 LHSD 107
H+D
Sbjct: 924 -HAD 926
>AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens
cDNA FLJ45589 fis, clone BRTHA3014547, weakly similar
to Ankyrin 1. ).
Length = 1375
Score = 78.6 bits (185), Expect = 3e-14
Identities = 56/194 (28%), Positives = 99/194 (51%), Gaps = 11/194 (5%)
Query: 58 EDLINNELKNNANI-KLDS-GWTPLMHACFHAQDKIVQYLLEKDADPNLHSD----SVTP 111
ED++ N L++ A + K D+ G T L+ A + +IV++LL+ A+ N H D +
Sbjct: 603 EDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVN-HEDVDGRTALS 661
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ A C +S + ++ S+ LIDR ++ D+ G TPL+ A G V V LL+
Sbjct: 662 VAALCVPASKGHASVVSL---LIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGA 718
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
+++ D +G T + A ++ L+ GA + +D RT+L IA+ + ++
Sbjct: 719 DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRT 778
Query: 232 LKKSLNLDDDHKTD 245
L LD++H+ D
Sbjct: 779 L-LDRGLDENHRDD 791
Score = 76.6 bits (180), Expect = 1e-13
Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 10/167 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ A + +V LLE AD + H+D+ TP++AA S A S+V L
Sbjct: 694 GMTPLLVAAYEGHVDVVDLLLEGGADVD-HTDNNGRTPLLAAASMGHA------SVVNTL 746
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ ++ D G+T L A + G V V + LLD ++ RD GWT + A
Sbjct: 747 LFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHR 806
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLD 239
I E LIE+GAR E+D R +A+ H ++I L+ N+D
Sbjct: 807 LICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNID 853
Score = 58.8 bits (136), Expect = 3e-08
Identities = 46/189 (24%), Positives = 79/189 (41%), Gaps = 9/189 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A GN++ V L++ L N + D+GWTPL A F I + L+E+ A N
Sbjct: 764 LSIASAQGNVEVVRTLLDRGLDENH--RDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 821
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ +D P + A Y V L++ ++ G+ L A G +
Sbjct: 822 IDNDGRIPFILASQEGH------YDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIV 875
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ L ++ +D G ++ NQ + E +E GA + D RT L ++
Sbjct: 876 ELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQ 935
Query: 224 DHQVIIEIL 232
H ++++L
Sbjct: 936 GHMEMVQVL 944
Score = 55.2 bits (127), Expect = 3e-07
Identities = 42/164 (25%), Positives = 71/164 (43%), Gaps = 7/164 (4%)
Query: 58 EDLINNELKNNANIKLDSGWTP-LMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
++++ +K A++ + T ++ +D I + LL+ A N + ++A
Sbjct: 440 QEVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSI-RTLLDNGASVNQCDSNGRTLLANA 498
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ S + +V L+ R L I D +G TPL A G V L+ NI
Sbjct: 499 AYSGS-----LDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHT 553
Query: 177 DQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
DQ GWTA+ A E++ L+ G ++ D +RT L A
Sbjct: 554 DQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAA 597
Score = 49.2 bits (112), Expect = 2e-05
Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 13/179 (7%)
Query: 60 LINNELK-NNANIKLDSGW--TPL---MHACFHAQDKIVQYLLEKDADPNLHSDSVTPIM 113
LIN+ L+ A + L W TP+ + + +++Q L++ A N D + I+
Sbjct: 405 LINSNLQLETAELALWMIWNGTPVRDSLSTLIPKEQEVLQLLVKAGAHVNSEDDRTSCIV 464
Query: 114 AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNI 173
D+I + L+D +N D G+T L A SG + V L+ ++
Sbjct: 465 RQALERE---DSIRT----LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADL 517
Query: 174 EMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E+ D HG T + A +++ LI GA + D+ T L A H ++ L
Sbjct: 518 EIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSAL 576
Score = 45.2 bits (102), Expect = 4e-04
Identities = 45/171 (26%), Positives = 73/171 (42%), Gaps = 11/171 (6%)
Query: 73 LDS-GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIV 130
+DS G T L A ++V+ LL++ D N D+ TP+ A + ++
Sbjct: 756 IDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEG-------HRLI 808
Query: 131 CN-LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
C LI++ N D G+ P + A G Q LL+ + NI+ R G A+ A
Sbjct: 809 CEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAAL 868
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIE-ILKKSLNLD 239
+I+E+L GA + D R L I + + E L+ N++
Sbjct: 869 EGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVE 919
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/177 (22%), Positives = 75/177 (42%), Gaps = 9/177 (5%)
Query: 59 DLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDAD-PNLHSDSVTPIMAA 115
D+++ L+ A++ ++G TPL+ A +V LL A ++ S+ T + A
Sbjct: 708 DVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIA 767
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + + +V L+DR N D G TPL A G + + L++
Sbjct: 768 SAQGNVE------VVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 821
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
D G A + +++L+E + + + R L +A H+ I+E+L
Sbjct: 822 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELL 878
Score = 30.7 bits (66), Expect = 8.3
Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
ALQ A G++K V+ LI + + + G T L A +VQ LLE ADPN
Sbjct: 961 ALQSAAWQGHVKVVQLLIEHGAV--VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPN 1018
Query: 104 LHSD 107
H+D
Sbjct: 1019 -HAD 1021
>AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein.
Length = 1089
Score = 78.6 bits (185), Expect = 3e-14
Identities = 56/194 (28%), Positives = 99/194 (51%), Gaps = 11/194 (5%)
Query: 58 EDLINNELKNNANI-KLDS-GWTPLMHACFHAQDKIVQYLLEKDADPNLHSD----SVTP 111
ED++ N L++ A + K D+ G T L+ A + +IV++LL+ A+ N H D +
Sbjct: 317 EDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVN-HEDVDGRTALS 375
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ A C +S + ++ S+ LIDR ++ D+ G TPL+ A G V V LL+
Sbjct: 376 VAALCVPASKGHASVVSL---LIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGA 432
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
+++ D +G T + A ++ L+ GA + +D RT+L IA+ + ++
Sbjct: 433 DVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRT 492
Query: 232 LKKSLNLDDDHKTD 245
L LD++H+ D
Sbjct: 493 L-LDRGLDENHRDD 505
Score = 76.6 bits (180), Expect = 1e-13
Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 10/167 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ A + +V LLE AD + H+D+ TP++AA S A S+V L
Sbjct: 408 GMTPLLVAAYEGHVDVVDLLLEGGADVD-HTDNNGRTPLLAAASMGHA------SVVNTL 460
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ ++ D G+T L A + G V V + LLD ++ RD GWT + A
Sbjct: 461 LFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHR 520
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLD 239
I E LIE+GAR E+D R +A+ H ++I L+ N+D
Sbjct: 521 LICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNID 567
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 7/173 (4%)
Query: 58 EDLINNELKNNANIKLDSGWTP-LMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
++++ +K A++ + T ++ +D I + LL+ A N + ++A
Sbjct: 154 QEVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSI-RTLLDNGASVNQCDSNGRTLLANA 212
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ S + +V L+ R L I D +G TPL A G V L+ NI
Sbjct: 213 AYSGS-----LDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHT 267
Query: 177 DQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVII 229
DQ GWTA+ A E++ L+ G ++ D +RT+L A H+ I+
Sbjct: 268 DQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHEDIV 320
Score = 58.8 bits (136), Expect = 3e-08
Identities = 46/189 (24%), Positives = 79/189 (41%), Gaps = 9/189 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A GN++ V L++ L N + D+GWTPL A F I + L+E+ A N
Sbjct: 478 LSIASAQGNVEVVRTLLDRGLDENH--RDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 535
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ +D P + A Y V L++ ++ G+ L A G +
Sbjct: 536 IDNDGRIPFILASQEGH------YDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIV 589
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ L ++ +D G ++ NQ + E +E GA + D RT L ++
Sbjct: 590 ELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQ 649
Query: 224 DHQVIIEIL 232
H ++++L
Sbjct: 650 GHMEMVQVL 658
Score = 49.2 bits (112), Expect = 2e-05
Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 13/179 (7%)
Query: 60 LINNELK-NNANIKLDSGW--TPL---MHACFHAQDKIVQYLLEKDADPNLHSDSVTPIM 113
LIN+ L+ A + L W TP+ + + +++Q L++ A N D + I+
Sbjct: 119 LINSNLQLETAELALWMIWNGTPVRDSLSTLIPKEQEVLQLLVKAGAHVNSEDDRTSCIV 178
Query: 114 AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNI 173
D+I + L+D +N D G+T L A SG + V L+ ++
Sbjct: 179 RQALERE---DSIRT----LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADL 231
Query: 174 EMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E+ D HG T + A +++ LI GA + D+ T L A H ++ L
Sbjct: 232 EIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSAL 290
Score = 45.2 bits (102), Expect = 4e-04
Identities = 45/171 (26%), Positives = 73/171 (42%), Gaps = 11/171 (6%)
Query: 73 LDS-GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIV 130
+DS G T L A ++V+ LL++ D N D+ TP+ A + ++
Sbjct: 470 IDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEG-------HRLI 522
Query: 131 CN-LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
C LI++ N D G+ P + A G Q LL+ + NI+ R G A+ A
Sbjct: 523 CEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAAL 582
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIE-ILKKSLNLD 239
+I+E+L GA + D R L I + + E L+ N++
Sbjct: 583 EGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVE 633
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/177 (22%), Positives = 75/177 (42%), Gaps = 9/177 (5%)
Query: 59 DLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDAD-PNLHSDSVTPIMAA 115
D+++ L+ A++ ++G TPL+ A +V LL A ++ S+ T + A
Sbjct: 422 DVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIA 481
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + + +V L+DR N D G TPL A G + + L++
Sbjct: 482 SAQGNVE------VVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 535
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
D G A + +++L+E + + + R L +A H+ I+E+L
Sbjct: 536 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELL 592
Score = 30.7 bits (66), Expect = 8.3
Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
ALQ A G++K V+ LI + + + G T L A +VQ LLE ADPN
Sbjct: 675 ALQSAAWQGHVKVVQLLIEHGAV--VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPN 732
Query: 104 LHSD 107
H+D
Sbjct: 733 -HAD 735
>BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein.
Length = 1672
Score = 77.4 bits (182), Expect = 7e-14
Identities = 55/190 (28%), Positives = 91/190 (47%), Gaps = 9/190 (4%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A G++ VE+L+ + N + GWT LM AC+ + +V+ LL A+P+
Sbjct: 32 ALISASKEGHVHIVEELLKCGV--NLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPS 89
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ SV PI+ A AD IV L+ +N D+YG TPL+ A G +
Sbjct: 90 VTGLYSVYPIIWAAGRGHAD------IVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLEC 143
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LL M +++ + TA+ AV + ++ ++++ + DK T L IA+
Sbjct: 144 VKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASK 203
Query: 223 HDHQVIIEIL 232
H I++ L
Sbjct: 204 EGHTEIVQDL 213
Score = 58.4 bits (135), Expect = 4e-08
Identities = 28/76 (36%), Positives = 42/76 (55%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
IV LI N+ D T L+ A G V + ++LL VN+E RD GWTA+ WA
Sbjct: 11 IVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWAC 70
Query: 189 HHNQPEILEMLIEKGA 204
+ + +++E+L+ GA
Sbjct: 71 YKGRTDVVELLLSHGA 86
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 11/194 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
AL A+ G + V+++ LK N N+ L G T LM A +IVQ LL+
Sbjct: 164 ALIVAVKGGYTQSVKEI----LKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTY 219
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
N+ S ++ IV L+ + ++I + +T L A+ G
Sbjct: 220 VNIPDRSGDTVLIGAVRGGH-----VEIVRALLQKYADIDIRGQDNKTALYWAVEKGNAT 274
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + +L + E+ + G T + A E++E+L++KGA+++ VDK T L IA
Sbjct: 275 MVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAI 334
Query: 222 CHDHQVIIEILKKS 235
+ + E+L ++
Sbjct: 335 RGRSRKLAELLLRN 348
Score = 54.4 bits (125), Expect = 6e-07
Identities = 44/171 (25%), Positives = 78/171 (45%), Gaps = 9/171 (5%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDR 136
T L+ A + V+ +L+++ + NL D T +M A + IV +L+D
Sbjct: 163 TALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTE------IVQDLLDA 216
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
+NI DR G T L+ A+ G V + + LL +I++R Q TA++WAV ++
Sbjct: 217 GTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMV 276
Query: 197 EMLIEKGARLTEVDKSNRT-LLEIANCHDHQVIIEILKKSLNLDD-DHKTD 245
+++ K T L++ + +V+ +L K + D K D
Sbjct: 277 RDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGD 327
>AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein.
Length = 1777
Score = 77.4 bits (182), Expect = 7e-14
Identities = 55/190 (28%), Positives = 91/190 (47%), Gaps = 9/190 (4%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A G++ VE+L+ + N + GWT LM AC+ + +V+ LL A+P+
Sbjct: 80 ALISASKEGHVHIVEELLKCGV--NLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPS 137
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ SV PI+ A AD IV L+ +N D+YG TPL+ A G +
Sbjct: 138 VTGLYSVYPIIWAAGRGHAD------IVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLEC 191
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LL M +++ + TA+ AV + ++ ++++ + DK T L IA+
Sbjct: 192 VKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASK 251
Query: 223 HDHQVIIEIL 232
H I++ L
Sbjct: 252 EGHTEIVQDL 261
Score = 62.1 bits (144), Expect = 3e-09
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Query: 95 LLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMR 153
LLEK D + ++ TP+M A + + IV LI N+ D T L+
Sbjct: 30 LLEKCKDVDERNECGQTPLMIAAEQGNLE------IVKELIKNGANCNLEDLDNWTALIS 83
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA 204
A G V + ++LL VN+E RD GWTA+ WA + + +++E+L+ GA
Sbjct: 84 ASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGA 134
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 11/194 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
AL A+ G + V+++ LK N N+ L G T LM A +IVQ LL+
Sbjct: 212 ALIVAVKGGYTQSVKEI----LKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTY 267
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
N+ S ++ IV L+ + ++I + +T L A+ G
Sbjct: 268 VNIPDRSGDTVLIGAVRGGH-----VEIVRALLQKYADIDIRGQDNKTALYWAVEKGNAT 322
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + +L + E+ + G T + A E++E+L++KGA+++ VDK T L IA
Sbjct: 323 MVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAI 382
Query: 222 CHDHQVIIEILKKS 235
+ + E+L ++
Sbjct: 383 RGRSRKLAELLLRN 396
Score = 54.4 bits (125), Expect = 6e-07
Identities = 44/171 (25%), Positives = 78/171 (45%), Gaps = 9/171 (5%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDR 136
T L+ A + V+ +L+++ + NL D T +M A + IV +L+D
Sbjct: 211 TALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTE------IVQDLLDA 264
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
+NI DR G T L+ A+ G V + + LL +I++R Q TA++WAV ++
Sbjct: 265 GTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMV 324
Query: 197 EMLIEKGARLTEVDKSNRT-LLEIANCHDHQVIIEILKKSLNLDD-DHKTD 245
+++ K T L++ + +V+ +L K + D K D
Sbjct: 325 RDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGD 375
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/86 (30%), Positives = 39/86 (45%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL 206
GQTPLM A G + + ++L+ N + D WTA+ A I+E L++ G L
Sbjct: 44 GQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNL 103
Query: 207 TEVDKSNRTLLEIANCHDHQVIIEIL 232
D T L A ++E+L
Sbjct: 104 EHRDMGGWTALMWACYKGRTDVVELL 129
>BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein.
Length = 743
Score = 76.6 bits (180), Expect = 1e-13
Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 10/167 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ A + +V LLE AD + H+D+ TP++AA S A S+V L
Sbjct: 62 GMTPLLVAAYEGHVDVVDLLLEGGADVD-HTDNNGRTPLLAAASMGHA------SVVNTL 114
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ ++ D G+T L A + G V V + LLD ++ RD GWT + A
Sbjct: 115 LFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHR 174
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLD 239
I E LIE+GAR E+D R +A+ H ++I L+ N+D
Sbjct: 175 LICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNID 221
Score = 66.1 bits (154), Expect = 2e-10
Identities = 45/160 (28%), Positives = 80/160 (50%), Gaps = 9/160 (5%)
Query: 90 KIVQYLLEKDADPNLHSD----SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDR 145
+IV++LL+ A+ N H D + + A C +S + ++ S+ LIDR ++ D+
Sbjct: 5 EIVEHLLDHGAEVN-HEDVDGRTALSVAALCVPASKGHASVVSL---LIDRGAEVDHCDK 60
Query: 146 YGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGAR 205
G TPL+ A G V V LL+ +++ D +G T + A ++ L+ GA
Sbjct: 61 DGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA 120
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTD 245
+ +D RT+L IA+ + ++ L LD++H+ D
Sbjct: 121 VDSIDSEGRTVLSIASAQGNVEVVRTL-LDRGLDENHRDD 159
Score = 58.8 bits (136), Expect = 3e-08
Identities = 46/189 (24%), Positives = 79/189 (41%), Gaps = 9/189 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A GN++ V L++ L N + D+GWTPL A F I + L+E+ A N
Sbjct: 132 LSIASAQGNVEVVRTLLDRGLDENH--RDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 189
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ +D P + A Y V L++ ++ G+ L A G +
Sbjct: 190 IDNDGRIPFILASQEGH------YDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIV 243
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ L ++ +D G ++ NQ + E +E GA + D RT L ++
Sbjct: 244 ELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQ 303
Query: 224 DHQVIIEIL 232
H ++++L
Sbjct: 304 GHMEMVQVL 312
Score = 45.2 bits (102), Expect = 4e-04
Identities = 45/171 (26%), Positives = 73/171 (42%), Gaps = 11/171 (6%)
Query: 73 LDS-GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIV 130
+DS G T L A ++V+ LL++ D N D+ TP+ A + ++
Sbjct: 124 IDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEG-------HRLI 176
Query: 131 CN-LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
C LI++ N D G+ P + A G Q LL+ + NI+ R G A+ A
Sbjct: 177 CEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAAL 236
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIE-ILKKSLNLD 239
+I+E+L GA + D R L I + + E L+ N++
Sbjct: 237 EGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVE 287
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/177 (22%), Positives = 75/177 (42%), Gaps = 9/177 (5%)
Query: 59 DLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDAD-PNLHSDSVTPIMAA 115
D+++ L+ A++ ++G TPL+ A +V LL A ++ S+ T + A
Sbjct: 76 DVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIA 135
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + + +V L+DR N D G TPL A G + + L++
Sbjct: 136 SAQGNVE------VVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 189
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
D G A + +++L+E + + + R L +A H+ I+E+L
Sbjct: 190 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELL 246
Score = 30.7 bits (66), Expect = 8.3
Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
ALQ A G++K V+ LI + + + G T L A +VQ LLE ADPN
Sbjct: 329 ALQSAAWQGHVKVVQLLIEHGAV--VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPN 386
Query: 104 LHSD 107
H+D
Sbjct: 387 -HAD 389
>AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein
protein.
Length = 1031
Score = 76.6 bits (180), Expect = 1e-13
Identities = 55/191 (28%), Positives = 91/191 (47%), Gaps = 10/191 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A G++ VE+L+ + N + GWT LM AC+ + +V+ LL A+P+
Sbjct: 74 ALISASKEGHVHIVEELLKCGV--NLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPS 131
Query: 104 LHS--DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ SV PI+ A AD IV L+ +N D+YG TPL+ A G +
Sbjct: 132 VTGLQYSVYPIIWAAGRGHAD------IVHLLLQNGAKVNCSDKYGTTPLVWAARKGHLE 185
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ LL M +++ + TA+ AV + ++ ++++ + DK T L IA+
Sbjct: 186 CVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIAS 245
Query: 222 CHDHQVIIEIL 232
H I++ L
Sbjct: 246 KEGHTEIVQDL 256
Score = 62.1 bits (144), Expect = 3e-09
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Query: 95 LLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMR 153
LLEK D + ++ TP+M A + + IV LI N+ D T L+
Sbjct: 24 LLEKCKDVDERNECGQTPLMIAAEQGNLE------IVKELIKNGANCNLEDLDNWTALIS 77
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA 204
A G V + ++LL VN+E RD GWTA+ WA + + +++E+L+ GA
Sbjct: 78 ASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGA 128
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/194 (25%), Positives = 88/194 (45%), Gaps = 11/194 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
AL A+ G + V+++ LK N N+ L G T LM A +IVQ LL+
Sbjct: 207 ALIVAVKGGYTQSVKEI----LKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTY 262
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
N+ S ++ IV L+ + ++I + +T L A+ G
Sbjct: 263 VNIPDRSGDTVLIGAVRGGH-----VEIVRALLQKYADIDIRGQDNKTALYWAVEKGNAT 317
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + +L + E+ + G T + A E++E+L++KGA+++ VDK T L IA
Sbjct: 318 MVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGDTPLHIAI 377
Query: 222 CHDHQVIIEILKKS 235
+ + E+L ++
Sbjct: 378 RGRSRKLAELLLRN 391
Score = 54.4 bits (125), Expect = 6e-07
Identities = 44/171 (25%), Positives = 78/171 (45%), Gaps = 9/171 (5%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDR 136
T L+ A + V+ +L+++ + NL D T +M A + IV +L+D
Sbjct: 206 TALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTE------IVQDLLDA 259
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
+NI DR G T L+ A+ G V + + LL +I++R Q TA++WAV ++
Sbjct: 260 GTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMV 319
Query: 197 EMLIEKGARLTEVDKSNRT-LLEIANCHDHQVIIEILKKSLNLDD-DHKTD 245
+++ K T L++ + +V+ +L K + D K D
Sbjct: 320 RDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGD 370
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/86 (30%), Positives = 39/86 (45%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL 206
GQTPLM A G + + ++L+ N + D WTA+ A I+E L++ G L
Sbjct: 38 GQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNL 97
Query: 207 TEVDKSNRTLLEIANCHDHQVIIEIL 232
D T L A ++E+L
Sbjct: 98 EHRDMGGWTALMWACYKGRTDVVELL 123
>BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III and
ankyrin repeat domains 1 protein.
Length = 345
Score = 72.5 bits (170), Expect = 2e-12
Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 13/195 (6%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A G + V+ L++N + N+K SG LM AC+ +V+YL A
Sbjct: 147 ALMVAAQKGYTRLVKILVSNG--TDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQ 204
Query: 104 LHSDSVTPIMAACS--NSSADNDTIYSIVCNLIDRNCILNIGDR-YGQTPLMRAIS-SGR 159
+ C+ + +AD S++ +I C +++ D G TPLMR + SG
Sbjct: 205 ARD------LGGCTALHWAADGGHC-SVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGN 257
Query: 160 VAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
VA L+D N+ ++D++G T + AV +N E++++L++KGA + ++ + +LE+
Sbjct: 258 QRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEM 317
Query: 220 ANCHDHQVIIEILKK 234
A D Q ++ +L++
Sbjct: 318 ARVFDRQSVVSLLEE 332
Score = 39.9 bits (89), Expect = 0.014
Identities = 30/129 (23%), Positives = 62/129 (48%), Gaps = 7/129 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G T L A +++++++ + ++ TP+M + S N + S+ L
Sbjct: 210 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSG--NQRVASL---L 264
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
ID +N+ DR G+TPLM A+ + + Q LLD + ++++ G + A ++
Sbjct: 265 IDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQ 324
Query: 194 EILEMLIEK 202
++ +L E+
Sbjct: 325 SVVSLLEER 333
>AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein.
Length = 371
Score = 72.5 bits (170), Expect = 2e-12
Identities = 56/195 (28%), Positives = 101/195 (51%), Gaps = 13/195 (6%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A G + V+ L++N + N+K SG LM AC+ +V+YL A
Sbjct: 173 ALMVAAQKGYTRLVKILVSNG--TDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQ 230
Query: 104 LHSDSVTPIMAACS--NSSADNDTIYSIVCNLIDRNCILNIGDR-YGQTPLMRAIS-SGR 159
+ C+ + +AD S++ +I C +++ D G TPLMR + SG
Sbjct: 231 ARD------LGGCTALHWAADGGHC-SVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGN 283
Query: 160 VAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
VA L+D N+ ++D++G T + AV +N E++++L++KGA + ++ + +LE+
Sbjct: 284 QRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEM 343
Query: 220 ANCHDHQVIIEILKK 234
A D Q ++ +L++
Sbjct: 344 ARVFDRQSVVSLLEE 358
Score = 39.9 bits (89), Expect = 0.014
Identities = 30/129 (23%), Positives = 62/129 (48%), Gaps = 7/129 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G T L A +++++++ + ++ TP+M + S N + S+ L
Sbjct: 236 GCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSG--NQRVASL---L 290
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
ID +N+ DR G+TPLM A+ + + Q LLD + ++++ G + A ++
Sbjct: 291 IDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQ 350
Query: 194 EILEMLIEK 202
++ +L E+
Sbjct: 351 SVVSLLEER 359
>AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein.
Length = 1644
Score = 72.1 bits (169), Expect = 3e-12
Identities = 53/208 (25%), Positives = 102/208 (49%), Gaps = 12/208 (5%)
Query: 41 VEVALQEAIINGNMKDVEDLINNELKNNANIK-LDSGW--TPLMHACFHAQDKIVQYLLE 97
++ AL A G+ V+ L+ E ++ + D+ W T L A + ++ + LL
Sbjct: 824 LQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLG 883
Query: 98 KDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAIS 156
A + + V P+ A + IV L++R C +N+ D+ G+TPLM A
Sbjct: 884 HGAAVSRTNRRGVPPLFCAARQGH------WQIVRLLLERGCDVNLSDKQGRTPLMVAAC 937
Query: 157 SGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTL 216
G ++ + LL + D+ G +A+ WA +++ L+E+GA + + DK+ RT
Sbjct: 938 EGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTP 997
Query: 217 LEIANCH-DHQVIIEILKKSLNLDD-DH 242
L++A + D + ++ +++K ++ DH
Sbjct: 998 LDLAAFYGDAETVLYLVEKGAVIEHVDH 1025
Score = 62.5 bits (145), Expect = 2e-09
Identities = 59/200 (29%), Positives = 89/200 (44%), Gaps = 12/200 (6%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A G ++ E L+ + + + G PL A +IV+ LLE+ D
Sbjct: 863 ETALTAAAGRGKLEVCELLLGHGAAVSRTNR--RGVPPLFCAARQGHWQIVRLLLERGCD 920
Query: 102 PNLHS-DSVTPIM-AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGR 159
NL TP+M AAC S V L+ + L+ D+ G + L A G
Sbjct: 921 VNLSDKQGRTPLMVAACEGH-------LSTVEFLLSKGAALSSLDKEGLSALSWACLKGH 973
Query: 160 VAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSN-RTLLE 218
AV Q L++ I+ D++G T + A + E + L+EKGA + VD S R L
Sbjct: 974 RAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDR 1033
Query: 219 IANCHDHQVIIEILKKSLNL 238
C + V++ +L+K L
Sbjct: 1034 AIGCRNTSVVVALLRKGAKL 1053
Score = 50.0 bits (114), Expect = 1e-05
Identities = 38/164 (23%), Positives = 66/164 (40%), Gaps = 7/164 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADP------NLHSDSVTPIMAACSNSSADNDTIYSI 129
G L+H+ I+QYLL + P L + S + + +
Sbjct: 784 GQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALTAAASMGHSSVVQCL 843
Query: 130 VCNLIDRNCILNIGDR-YGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+ + +N D +G+T L A G++ V + LL + ++ G +F A
Sbjct: 844 LGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAA 903
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+I+ +L+E+G + DK RT L +A C H +E L
Sbjct: 904 RQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFL 947
Score = 44.0 bits (99), Expect = 8e-04
Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 19/168 (11%)
Query: 37 SKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDS-GWTPLMHACFHAQDKIVQYL 95
S K+ L A G++ VE L++ K A LD G + L AC +VQYL
Sbjct: 924 SDKQGRTPLMVAACEGHLSTVEFLLS---KGAALSSLDKEGLSALSWACLKGHRAVVQYL 980
Query: 96 LEKDAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
+E+ A + TP+ A A+ V L+++ ++ D G PL RA
Sbjct: 981 VEEGAAIDQTDKNGRTPLDLAAFYGDAET------VLYLVEKGAVIEHVDHSGMRPLDRA 1034
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEK 202
I +V LL + G A WA+ ++P+IL +L++K
Sbjct: 1035 IGCRNTSVVVALLRKGAKL------GNAA--WAMATSKPDILIILLQK 1074
Score = 31.5 bits (68), Expect = 4.8
Identities = 18/75 (24%), Positives = 36/75 (48%)
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
G V LL+ ++ ++G TA+ +A +++ +L +KG R+ +DK + L
Sbjct: 729 GHEEVVTLLLEFGACLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCAL 788
Query: 218 EIANCHDHQVIIEIL 232
+ H I++ L
Sbjct: 789 VHSALRGHGDILQYL 803
>BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 70.9 bits (166), Expect = 6e-12
Identities = 63/213 (29%), Positives = 100/213 (46%), Gaps = 17/213 (7%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGW-TPLMHACFHAQDKIVQYLLEKDADPN 103
L A G+ + +E LI + + NA DS W TPL A ++ VQ LL+ AD N
Sbjct: 78 LHAAAYLGDAEIIELLILSGARVNAK---DSKWLTPLHRAVASCSEEAVQVLLKHSADVN 134
Query: 104 LHSDS-VTPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ TP+ A +N + + + ++ N+ N+ DR G+T L A SG
Sbjct: 135 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNV-------NVSDRAGRTALHHAAFSGHGE 187
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL NI D+ A+ WA + E++++L+ GA +T DK + T L A
Sbjct: 188 MVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA 247
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSYLNHQL 254
+I ++K L+L D + N+Y N L
Sbjct: 248 SSG---MISVVKYLLDLGVD-MNEPNAYGNTPL 276
Score = 68.5 bits (160), Expect = 3e-11
Identities = 57/224 (25%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Query: 12 EDSDSDDYGFYEK-PVRNYDYSSQISSKKKVEV-ALQEAIINGNMKDVEDLINNELKNNA 69
E+ + + F K P N S S V +L +AI NG+ +V LI K +
Sbjct: 10 EEVEDESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFK--KEDV 67
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYS 128
N + + TPL A + +I++ L+ A N +TP+ A ++ S + +
Sbjct: 68 NFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV-- 125
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
L+ + +N D+ QTPL A ++ V A+ L+ + N+ + D+ G TA+ A
Sbjct: 126 ----LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAA 181
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E++++L+ +GA + DK +R + A H ++++L
Sbjct: 182 FSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLL 225
Score = 64.9 bits (151), Expect = 4e-10
Identities = 55/204 (26%), Positives = 101/204 (49%), Gaps = 10/204 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A +G+ + +E L+ + L + +++ SG TPL A F + V L+ + A L
Sbjct: 587 LHLAAYHGHHQALEVLVQSLL--DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI-L 643
Query: 105 HSDSV---TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
D + TPI AA +N ++ + ++ N +N + +I D GQTPLM ++ +G
Sbjct: 644 VKDYILKRTPIHAAATNGHSE--CLRLLIGNAEPQNAV-DIQDGNGQTPLMLSVLNGHTD 700
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI-A 220
LL+ N++ +D+ G TA+ E ++ L++ GA+ D RT + + A
Sbjct: 701 CVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSA 760
Query: 221 NCHDHQVIIEILKKSLNLDDDHKT 244
C V+ +L+ + ++D + T
Sbjct: 761 ACGHIGVLGALLQSAASMDANPAT 784
Score = 60.1 bits (139), Expect = 1e-08
Identities = 56/198 (28%), Positives = 93/198 (46%), Gaps = 14/198 (7%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
KK A+ A G+++ V+ L+++ + K +TPL A +V+YLL+
Sbjct: 204 KKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDK--KSYTPLHAAASSGMISVVKYLLDL 261
Query: 99 DAD---PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
D PN + + TP+ AC N D + V LID I+N + G TPL A
Sbjct: 262 GVDMNEPNAYGN--TPLHVACYNGQ---DVV---VNELIDCGAIVNQKNEKGFTPLHFAA 313
Query: 156 SSGRVAVAQKLL-DMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+S A+ +LL ++ M+ + G T + H + + +I+ GA + DK+
Sbjct: 314 ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGN 373
Query: 215 TLLEIANCHDHQVIIEIL 232
T L IA + H+++I L
Sbjct: 374 TPLHIAARYGHELLINTL 391
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E L+ L +N N+ +G T L HA F
Sbjct: 129 HSADVNARDKNWQTPLHIAAANKAVKCAEALV--PLLSNVNVSDRAGRTALHHAAFSGHG 186
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V+ LL + A+ N + + +V L+ + D+ T
Sbjct: 187 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGH-----IEVVKLLVSHGAEVTCKDKKSYT 241
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A SSG ++V + LLD+ V++ + +G T + A ++ Q ++ LI+ GA + +
Sbjct: 242 PLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQK 301
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
++ T L A H + +E+L
Sbjct: 302 NEKGFTPLHFAAASTHGALCLELL 325
Score = 40.3 bits (90), Expect = 0.010
Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 13/169 (7%)
Query: 58 EDLINNELKNNA---NIKLDSGWTPLMHACFHAQDKI-VQYLLEKDADPNLHS-DSVTPI 112
+D++ NEL + N K + G+TPL A + ++ L+ AD N+ S D TP+
Sbjct: 284 QDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPL 343
Query: 113 -MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
M A + + TI I +++ D+ G TPL A G + L+
Sbjct: 344 HMTALHGRFSRSQTI-------IQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 396
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ R HG + A + L+ G + D RT L A
Sbjct: 397 DTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAA 445
Score = 37.5 bits (83), Expect = 0.072
Identities = 37/168 (22%), Positives = 72/168 (42%), Gaps = 9/168 (5%)
Query: 74 DSGWTPLMHACFHAQD-KIVQYLLEKDADPNLHSD---SVTPIMAACSN----SSADNDT 125
+ G TPL +A D K ++YLL DA+P + + AA + ++T
Sbjct: 502 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 561
Query: 126 IYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVF 185
++ + + + +R +PL A G + L+ +++++R+ G T +
Sbjct: 562 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 621
Query: 186 WAVHHNQPEILEMLIEKGARLTEVDK-SNRTLLEIANCHDHQVIIEIL 232
A E +++LI +GA + D RT + A + H + +L
Sbjct: 622 LAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLL 669
Score = 34.7 bits (76), Expect = 0.51
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVD 210
L++AI +G + L+ + ++ +D T + A + EI+E+LI GAR+ D
Sbjct: 45 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKD 104
Query: 211 KSNRTLLE--IANCHDHQVIIEILKKSLNLD 239
T L +A+C + V + +LK S +++
Sbjct: 105 SKWLTPLHRAVASCSEEAVQV-LLKHSADVN 134
Score = 31.5 bits (68), Expect = 4.8
Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW-AVHHN 191
L++ N D++G++PL A ++ L+ ++ D+ G T + + A
Sbjct: 457 LLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDT 516
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
+ LE L+ A DK + + + H++ ++++ LD
Sbjct: 517 DGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLD 564
>BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein.
Length = 782
Score = 70.9 bits (166), Expect = 6e-12
Identities = 63/213 (29%), Positives = 100/213 (46%), Gaps = 17/213 (7%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGW-TPLMHACFHAQDKIVQYLLEKDADPN 103
L A G+ + +E LI + + NA DS W TPL A ++ VQ LL+ AD N
Sbjct: 75 LHAAAYLGDAEIIELLILSGARVNAK---DSKWLTPLHRAVASCSEEAVQVLLKHSADVN 131
Query: 104 LHSDS-VTPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ TP+ A +N + + + ++ N+ N+ DR G+T L A SG
Sbjct: 132 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNV-------NVSDRAGRTALHHAAFSGHGE 184
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL NI D+ A+ WA + E++++L+ GA +T DK + T L A
Sbjct: 185 MVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA 244
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSYLNHQL 254
+I ++K L+L D + N+Y N L
Sbjct: 245 SSG---MISVVKYLLDLGVD-MNEPNAYGNTPL 273
Score = 67.7 bits (158), Expect = 6e-11
Identities = 57/223 (25%), Positives = 104/223 (46%), Gaps = 12/223 (5%)
Query: 12 EDSDSDDYGFYEK-PVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNAN 70
E+ + + F K P N S S V +L +AI NG+ +V LI K + N
Sbjct: 10 EEVEDESPAFISKLPQENKSLHSPPSGN--VLPSLVQAIFNGDPDEVRALIFK--KEDVN 65
Query: 71 IKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSI 129
+ + TPL A + +I++ L+ A N +TP+ A ++ S + +
Sbjct: 66 FQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV--- 122
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
L+ + +N D+ QTPL A ++ V A+ L+ + N+ + D+ G TA+ A
Sbjct: 123 ---LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAF 179
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E++++L+ +GA + DK +R + A H ++++L
Sbjct: 180 SGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLL 222
Score = 64.9 bits (151), Expect = 4e-10
Identities = 55/204 (26%), Positives = 101/204 (49%), Gaps = 10/204 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A +G+ + +E L+ + L + +++ SG TPL A F + V L+ + A L
Sbjct: 584 LHLAAYHGHHQALEVLVQSLL--DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI-L 640
Query: 105 HSDSV---TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
D + TPI AA +N ++ + ++ N +N + +I D GQTPLM ++ +G
Sbjct: 641 VKDYILKRTPIHAAATNGHSE--CLRLLIGNAEPQNAV-DIQDGNGQTPLMLSVLNGHTD 697
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI-A 220
LL+ N++ +D+ G TA+ E ++ L++ GA+ D RT + + A
Sbjct: 698 CVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSA 757
Query: 221 NCHDHQVIIEILKKSLNLDDDHKT 244
C V+ +L+ + ++D + T
Sbjct: 758 ACGHIGVLGALLQSAASMDANPAT 781
Score = 60.1 bits (139), Expect = 1e-08
Identities = 56/198 (28%), Positives = 93/198 (46%), Gaps = 14/198 (7%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
KK A+ A G+++ V+ L+++ + K +TPL A +V+YLL+
Sbjct: 201 KKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDK--KSYTPLHAAASSGMISVVKYLLDL 258
Query: 99 DAD---PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
D PN + + TP+ AC N D + V LID I+N + G TPL A
Sbjct: 259 GVDMNEPNAYGN--TPLHVACYNGQ---DVV---VNELIDCGAIVNQKNEKGFTPLHFAA 310
Query: 156 SSGRVAVAQKLL-DMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+S A+ +LL ++ M+ + G T + H + + +I+ GA + DK+
Sbjct: 311 ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGN 370
Query: 215 TLLEIANCHDHQVIIEIL 232
T L IA + H+++I L
Sbjct: 371 TPLHIAARYGHELLINTL 388
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E L+ L +N N+ +G T L HA F
Sbjct: 126 HSADVNARDKNWQTPLHIAAANKAVKCAEALV--PLLSNVNVSDRAGRTALHHAAFSGHG 183
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V+ LL + A+ N + + +V L+ + D+ T
Sbjct: 184 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGH-----IEVVKLLVSHGAEVTCKDKKSYT 238
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A SSG ++V + LLD+ V++ + +G T + A ++ Q ++ LI+ GA + +
Sbjct: 239 PLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQK 298
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
++ T L A H + +E+L
Sbjct: 299 NEKGFTPLHFAAASTHGALCLELL 322
Score = 40.3 bits (90), Expect = 0.010
Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 13/169 (7%)
Query: 58 EDLINNELKNNA---NIKLDSGWTPLMHACFHAQDKI-VQYLLEKDADPNLHS-DSVTPI 112
+D++ NEL + N K + G+TPL A + ++ L+ AD N+ S D TP+
Sbjct: 281 QDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPL 340
Query: 113 -MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
M A + + TI I +++ D+ G TPL A G + L+
Sbjct: 341 HMTALHGRFSRSQTI-------IQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 393
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ R HG + A + L+ G + D RT L A
Sbjct: 394 DTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAA 442
Score = 37.5 bits (83), Expect = 0.072
Identities = 37/168 (22%), Positives = 72/168 (42%), Gaps = 9/168 (5%)
Query: 74 DSGWTPLMHACFHAQD-KIVQYLLEKDADPNLHSD---SVTPIMAACSN----SSADNDT 125
+ G TPL +A D K ++YLL DA+P + + AA + ++T
Sbjct: 499 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 558
Query: 126 IYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVF 185
++ + + + +R +PL A G + L+ +++++R+ G T +
Sbjct: 559 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 618
Query: 186 WAVHHNQPEILEMLIEKGARLTEVDK-SNRTLLEIANCHDHQVIIEIL 232
A E +++LI +GA + D RT + A + H + +L
Sbjct: 619 LAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLL 666
Score = 34.7 bits (76), Expect = 0.51
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVD 210
L++AI +G + L+ + ++ +D T + A + EI+E+LI GAR+ D
Sbjct: 42 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKD 101
Query: 211 KSNRTLLE--IANCHDHQVIIEILKKSLNLD 239
T L +A+C + V + +LK S +++
Sbjct: 102 SKWLTPLHRAVASCSEEAVQV-LLKHSADVN 131
Score = 31.5 bits (68), Expect = 4.8
Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW-AVHHN 191
L++ N D++G++PL A ++ L+ ++ D+ G T + + A
Sbjct: 454 LLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDT 513
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
+ LE L+ A DK + + + H++ ++++ LD
Sbjct: 514 DGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLD 561
>BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 70.9 bits (166), Expect = 6e-12
Identities = 63/213 (29%), Positives = 100/213 (46%), Gaps = 17/213 (7%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGW-TPLMHACFHAQDKIVQYLLEKDADPN 103
L A G+ + +E LI + + NA DS W TPL A ++ VQ LL+ AD N
Sbjct: 78 LHAAAYLGDAEIIELLILSGARVNAK---DSKWLTPLHRAVASCSEEAVQVLLKHSADVN 134
Query: 104 LHSDS-VTPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ TP+ A +N + + + ++ N+ N+ DR G+T L A SG
Sbjct: 135 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNV-------NVSDRAGRTALHHAAFSGHGE 187
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL NI D+ A+ WA + E++++L+ GA +T DK + T L A
Sbjct: 188 MVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA 247
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSYLNHQL 254
+I ++K L+L D + N+Y N L
Sbjct: 248 SSG---MISVVKYLLDLGVD-MNEPNAYGNTPL 276
Score = 68.5 bits (160), Expect = 3e-11
Identities = 57/224 (25%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Query: 12 EDSDSDDYGFYEK-PVRNYDYSSQISSKKKVEV-ALQEAIINGNMKDVEDLINNELKNNA 69
E+ + + F K P N S S V +L +AI NG+ +V LI K +
Sbjct: 10 EEVEDESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFK--KEDV 67
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYS 128
N + + TPL A + +I++ L+ A N +TP+ A ++ S + +
Sbjct: 68 NFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV-- 125
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
L+ + +N D+ QTPL A ++ V A+ L+ + N+ + D+ G TA+ A
Sbjct: 126 ----LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAA 181
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E++++L+ +GA + DK +R + A H ++++L
Sbjct: 182 FSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLL 225
Score = 64.9 bits (151), Expect = 4e-10
Identities = 55/204 (26%), Positives = 101/204 (49%), Gaps = 10/204 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A +G+ + +E L+ + L + +++ SG TPL A F + V L+ + A L
Sbjct: 587 LHLAAYHGHHQALEVLVQSLL--DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI-L 643
Query: 105 HSDSV---TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
D + TPI AA +N ++ + ++ N +N + +I D GQTPLM ++ +G
Sbjct: 644 VKDYILKRTPIHAAATNGHSE--CLRLLIGNAEPQNAV-DIQDGNGQTPLMLSVLNGHTD 700
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI-A 220
LL+ N++ +D+ G TA+ E ++ L++ GA+ D RT + + A
Sbjct: 701 CVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSA 760
Query: 221 NCHDHQVIIEILKKSLNLDDDHKT 244
C V+ +L+ + ++D + T
Sbjct: 761 ACGHIGVLGALLQSAASMDANPAT 784
Score = 60.1 bits (139), Expect = 1e-08
Identities = 56/198 (28%), Positives = 93/198 (46%), Gaps = 14/198 (7%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
KK A+ A G+++ V+ L+++ + K +TPL A +V+YLL+
Sbjct: 204 KKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDK--KSYTPLHAAASSGMISVVKYLLDL 261
Query: 99 DAD---PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
D PN + + TP+ AC N D + V LID I+N + G TPL A
Sbjct: 262 GVDMNEPNAYGN--TPLHVACYNGQ---DVV---VNELIDCGAIVNQKNEKGFTPLHFAA 313
Query: 156 SSGRVAVAQKLL-DMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+S A+ +LL ++ M+ + G T + H + + +I+ GA + DK+
Sbjct: 314 ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGN 373
Query: 215 TLLEIANCHDHQVIIEIL 232
T L IA + H+++I L
Sbjct: 374 TPLHIAARYGHELLINTL 391
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E L+ L +N N+ +G T L HA F
Sbjct: 129 HSADVNARDKNWQTPLHIAAANKAVKCAEALV--PLLSNVNVSDRAGRTALHHAAFSGHG 186
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V+ LL + A+ N + + +V L+ + D+ T
Sbjct: 187 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGH-----IEVVKLLVSHGAEVTCKDKKSYT 241
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A SSG ++V + LLD+ V++ + +G T + A ++ Q ++ LI+ GA + +
Sbjct: 242 PLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQK 301
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
++ T L A H + +E+L
Sbjct: 302 NEKGFTPLHFAAASTHGALCLELL 325
Score = 40.3 bits (90), Expect = 0.010
Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 13/169 (7%)
Query: 58 EDLINNELKNNA---NIKLDSGWTPLMHACFHAQDKI-VQYLLEKDADPNLHS-DSVTPI 112
+D++ NEL + N K + G+TPL A + ++ L+ AD N+ S D TP+
Sbjct: 284 QDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPL 343
Query: 113 -MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
M A + + TI I +++ D+ G TPL A G + L+
Sbjct: 344 HMTALHGRFSRSQTI-------IQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 396
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ R HG + A + L+ G + D RT L A
Sbjct: 397 DTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAA 445
Score = 37.5 bits (83), Expect = 0.072
Identities = 37/168 (22%), Positives = 72/168 (42%), Gaps = 9/168 (5%)
Query: 74 DSGWTPLMHACFHAQD-KIVQYLLEKDADPNLHSD---SVTPIMAACSN----SSADNDT 125
+ G TPL +A D K ++YLL DA+P + + AA + ++T
Sbjct: 502 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 561
Query: 126 IYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVF 185
++ + + + +R +PL A G + L+ +++++R+ G T +
Sbjct: 562 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 621
Query: 186 WAVHHNQPEILEMLIEKGARLTEVDK-SNRTLLEIANCHDHQVIIEIL 232
A E +++LI +GA + D RT + A + H + +L
Sbjct: 622 LAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLL 669
Score = 34.7 bits (76), Expect = 0.51
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVD 210
L++AI +G + L+ + ++ +D T + A + EI+E+LI GAR+ D
Sbjct: 45 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKD 104
Query: 211 KSNRTLLE--IANCHDHQVIIEILKKSLNLD 239
T L +A+C + V + +LK S +++
Sbjct: 105 SKWLTPLHRAVASCSEEAVQV-LLKHSADVN 134
Score = 31.5 bits (68), Expect = 4.8
Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW-AVHHN 191
L++ N D++G++PL A ++ L+ ++ D+ G T + + A
Sbjct: 457 LLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDT 516
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
+ LE L+ A DK + + + H++ ++++ LD
Sbjct: 517 DGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLD 564
>AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens
cDNA FLJ44940 fis, clone BRAMY4000915, weakly similar
to Ankyrin 1. ).
Length = 687
Score = 70.9 bits (166), Expect = 6e-12
Identities = 63/213 (29%), Positives = 100/213 (46%), Gaps = 17/213 (7%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGW-TPLMHACFHAQDKIVQYLLEKDADPN 103
L A G+ + +E LI + + NA DS W TPL A ++ VQ LL+ AD N
Sbjct: 78 LHAAAYLGDAEIIELLILSGARVNAK---DSKWLTPLHRAVASCSEEAVQVLLKHSADVN 134
Query: 104 LHSDS-VTPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ TP+ A +N + + + ++ N+ N+ DR G+T L A SG
Sbjct: 135 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNV-------NVSDRAGRTALHHAAFSGHGE 187
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL NI D+ A+ WA + E++++L+ GA +T DK + T L A
Sbjct: 188 MVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA 247
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSYLNHQL 254
+I ++K L+L D + N+Y N L
Sbjct: 248 SSG---MISVVKYLLDLGVD-MNEPNAYGNTPL 276
Score = 68.5 bits (160), Expect = 3e-11
Identities = 57/224 (25%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Query: 12 EDSDSDDYGFYEK-PVRNYDYSSQISSKKKVEV-ALQEAIINGNMKDVEDLINNELKNNA 69
E+ + + F K P N S S V +L +AI NG+ +V LI K +
Sbjct: 10 EEVEDESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFK--KEDV 67
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYS 128
N + + TPL A + +I++ L+ A N +TP+ A ++ S + +
Sbjct: 68 NFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQV-- 125
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
L+ + +N D+ QTPL A ++ V A+ L+ + N+ + D+ G TA+ A
Sbjct: 126 ----LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAA 181
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E++++L+ +GA + DK +R + A H ++++L
Sbjct: 182 FSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLL 225
Score = 60.1 bits (139), Expect = 1e-08
Identities = 56/198 (28%), Positives = 93/198 (46%), Gaps = 14/198 (7%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
KK A+ A G+++ V+ L+++ + K +TPL A +V+YLL+
Sbjct: 204 KKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDK--KSYTPLHAAASSGMISVVKYLLDL 261
Query: 99 DAD---PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
D PN + + TP+ AC N D + V LID I+N + G TPL A
Sbjct: 262 GVDMNEPNAYGN--TPLHVACYNGQ---DVV---VNELIDCGAIVNQKNEKGFTPLHFAA 313
Query: 156 SSGRVAVAQKLL-DMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+S A+ +LL ++ M+ + G T + H + + +I+ GA + DK+
Sbjct: 314 ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGN 373
Query: 215 TLLEIANCHDHQVIIEIL 232
T L IA + H+++I L
Sbjct: 374 TPLHIAARYGHELLINTL 391
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E L+ L +N N+ +G T L HA F
Sbjct: 129 HSADVNARDKNWQTPLHIAAANKAVKCAEALV--PLLSNVNVSDRAGRTALHHAAFSGHG 186
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V+ LL + A+ N + + +V L+ + D+ T
Sbjct: 187 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGH-----IEVVKLLVSHGAEVTCKDKKSYT 241
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A SSG ++V + LLD+ V++ + +G T + A ++ Q ++ LI+ GA + +
Sbjct: 242 PLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQK 301
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
++ T L A H + +E+L
Sbjct: 302 NEKGFTPLHFAAASTHGALCLELL 325
Score = 40.3 bits (90), Expect = 0.010
Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 13/169 (7%)
Query: 58 EDLINNELKNNA---NIKLDSGWTPLMHACFHAQDKI-VQYLLEKDADPNLHS-DSVTPI 112
+D++ NEL + N K + G+TPL A + ++ L+ AD N+ S D TP+
Sbjct: 284 QDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPL 343
Query: 113 -MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
M A + + TI I +++ D+ G TPL A G + L+
Sbjct: 344 HMTALHGRFSRSQTI-------IQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 396
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ R HG + A + L+ G + D RT L A
Sbjct: 397 DTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAA 445
Score = 37.1 bits (82), Expect = 0.096
Identities = 37/168 (22%), Positives = 72/168 (42%), Gaps = 9/168 (5%)
Query: 74 DSGWTPLMHACFHAQD-KIVQYLLEKDADPNLHSD---SVTPIMAACSN----SSADNDT 125
+ G TPL +A D K ++YLL DA+P + + AA + ++T
Sbjct: 502 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASET 561
Query: 126 IYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVF 185
++ + + + +R +PL A G + L+ +++++R+ G T +
Sbjct: 562 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 621
Query: 186 WAVHHNQPEILEMLIEKGARLTEVDK-SNRTLLEIANCHDHQVIIEIL 232
A E +++LI +GA + D RT + A + H + +L
Sbjct: 622 LAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLL 669
Score = 34.7 bits (76), Expect = 0.51
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVD 210
L++AI +G + L+ + ++ +D T + A + EI+E+LI GAR+ D
Sbjct: 45 LVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKD 104
Query: 211 KSNRTLLE--IANCHDHQVIIEILKKSLNLD 239
T L +A+C + V + +LK S +++
Sbjct: 105 SKWLTPLHRAVASCSEEAVQV-LLKHSADVN 134
Score = 31.9 bits (69), Expect = 3.6
Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW-AVHHN 191
L++ N D++G++PL A ++ L+ ++ D+ G T + + A
Sbjct: 457 LLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDT 516
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
+ LE L+ A DK + + + H++ ++++ LD
Sbjct: 517 DGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASETPLD 564
>AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein.
Length = 1059
Score = 70.9 bits (166), Expect = 6e-12
Identities = 63/213 (29%), Positives = 100/213 (46%), Gaps = 17/213 (7%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGW-TPLMHACFHAQDKIVQYLLEKDADPN 103
L A G+ + +E LI + + NA DS W TPL A ++ VQ LL+ AD N
Sbjct: 51 LHAAAYLGDAEIIELLILSGARVNAK---DSKWLTPLHRAVASCSEEAVQVLLKHSADVN 107
Query: 104 LHSDS-VTPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ TP+ A +N + + + ++ N+ N+ DR G+T L A SG
Sbjct: 108 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNV-------NVSDRAGRTALHHAAFSGHGE 160
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL NI D+ A+ WA + E++++L+ GA +T DK + T L A
Sbjct: 161 MVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA 220
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSYLNHQL 254
+I ++K L+L D + N+Y N L
Sbjct: 221 SSG---MISVVKYLLDLGVD-MNEPNAYGNTPL 249
Score = 67.7 bits (158), Expect = 6e-11
Identities = 50/196 (25%), Positives = 96/196 (48%), Gaps = 9/196 (4%)
Query: 38 KKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLE 97
K + + +L +AI NG+ +V LI K + N + + TPL A + +I++ L+
Sbjct: 11 KLRDQPSLVQAIFNGDPDEVRALIFK--KEDVNFQDNEKRTPLHAAAYLGDAEIIELLIL 68
Query: 98 KDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAIS 156
A N +TP+ A ++ S + + L+ + +N D+ QTPL A +
Sbjct: 69 SGARVNAKDSKWLTPLHRAVASCSEEAVQV------LLKHSADVNARDKNWQTPLHIAAA 122
Query: 157 SGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTL 216
+ V A+ L+ + N+ + D+ G TA+ A E++++L+ +GA + DK +R
Sbjct: 123 NKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRA 182
Query: 217 LEIANCHDHQVIIEIL 232
+ A H ++++L
Sbjct: 183 IHWAAYMGHIEVVKLL 198
Score = 67.3 bits (157), Expect = 8e-11
Identities = 56/207 (27%), Positives = 103/207 (49%), Gaps = 10/207 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A +G+ + +E L+ + L + +++ SG TPL A F + V L+ + A L
Sbjct: 560 LHLAAYHGHHQALEVLVQSLL--DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI-L 616
Query: 105 HSDSV---TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
D + TPI AA +N ++ + ++ N +N + +I D GQTPLM ++ +G
Sbjct: 617 VKDYILKRTPIHAAATNGHSE--CLRLLIGNAEPQNAV-DIQDGNGQTPLMLSVLNGHTD 673
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI-A 220
LL+ N++ +D+ G TA+ E ++ L++ GA+ D RT + + A
Sbjct: 674 CVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSA 733
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDEN 247
C V+ +L+ + ++D + T +N
Sbjct: 734 ACGHIGVLGALLQSAASMDANPATADN 760
Score = 64.5 bits (150), Expect = 6e-10
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 6/161 (3%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLID 135
G+T L AC++ + V+ LLE++ ++ +P+ A N DN+ ++ + +
Sbjct: 762 GYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVIN---DNEGAAEMLIDTLG 818
Query: 136 RNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
+ I+N D G+TPL A + V Q LL + D G T + A + Q
Sbjct: 819 AS-IVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNT 877
Query: 196 LEMLIEK-GARLTEVDKSNRTLLEIANCHDHQV-IIEILKK 234
+EML+ A LT D S T L +A H+ + IL+K
Sbjct: 878 VEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEK 918
Score = 60.1 bits (139), Expect = 1e-08
Identities = 56/198 (28%), Positives = 93/198 (46%), Gaps = 14/198 (7%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
KK A+ A G+++ V+ L+++ + K +TPL A +V+YLL+
Sbjct: 177 KKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDK--KSYTPLHAAASSGMISVVKYLLDL 234
Query: 99 DAD---PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
D PN + + TP+ AC N D + V LID I+N + G TPL A
Sbjct: 235 GVDMNEPNAYGN--TPLHVACYNGQ---DVV---VNELIDCGAIVNQKNEKGFTPLHFAA 286
Query: 156 SSGRVAVAQKLL-DMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+S A+ +LL ++ M+ + G T + H + + +I+ GA + DK+
Sbjct: 287 ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGN 346
Query: 215 TLLEIANCHDHQVIIEIL 232
T L IA + H+++I L
Sbjct: 347 TPLHIAARYGHELLINTL 364
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/204 (25%), Positives = 95/204 (46%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E L+ L +N N+ +G T L HA F
Sbjct: 102 HSADVNARDKNWQTPLHIAAANKAVKCAEALV--PLLSNVNVSDRAGRTALHHAAFSGHG 159
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V+ LL + A+ N + + +V L+ + D+ T
Sbjct: 160 EMVKLLLSRGANINAFDKKDRRAIHWAAYMGH-----IEVVKLLVSHGAEVTCKDKKSYT 214
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A SSG ++V + LLD+ V++ + +G T + A ++ Q ++ LI+ GA + +
Sbjct: 215 PLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQK 274
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
++ T L A H + +E+L
Sbjct: 275 NEKGFTPLHFAAASTHGALCLELL 298
Score = 51.6 bits (118), Expect = 4e-06
Identities = 50/206 (24%), Positives = 93/206 (45%), Gaps = 11/206 (5%)
Query: 45 LQEAIINGNMKDVEDLINN-ELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ A NG+ + + LI N E +N +I+ +G TPLM + + V LL K A+ +
Sbjct: 627 IHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVD 686
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
D + + + +++ + C+L D G+TP+ + + G + V
Sbjct: 687 A-KDKWGRTALHRGAVTGHEECVDALLQH--GAKCLLR--DSRGRTPIHLSAACGHIGVL 741
Query: 164 QKLLD----MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
LL M N D HG+TA+ WA ++ +E+L+E+ + + + + L
Sbjct: 742 GALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEV-FQKTEGNAFSPLHC 800
Query: 220 ANCHDHQVIIEILKKSLNLDDDHKTD 245
A +D++ E+L +L + TD
Sbjct: 801 AVINDNEGAAEMLIDTLGASIVNATD 826
Score = 44.4 bits (100), Expect = 6e-04
Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 7/122 (5%)
Query: 65 LKNNANIK-LDS-GWTPLMHACFHAQDKIVQYLLEK-DADPNLHSDSV-TPIMAACSNSS 120
L +NA + +DS G TPLM A + Q V+ L+ A+ L +S T + ACS
Sbjct: 849 LSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGH 908
Query: 121 ADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG 180
+ + I+ + DRN ++N + QTPL A +G V Q+LL ++ D++G
Sbjct: 909 ETSALL--ILEKITDRN-LINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENG 965
Query: 181 WT 182
+T
Sbjct: 966 YT 967
Score = 43.2 bits (97), Expect = 0.001
Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 11/173 (6%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
A+IN N E LI+ + N G TPL A F + +Q LL +A N + S
Sbjct: 801 AVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDS 860
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGR----VAV 162
TP+M A N +T+ +V + + L + D T L A S G + +
Sbjct: 861 TGKTPLMMAAEN--GQTNTVEMLVSS---ASAELTLQDNSKNTALHLACSKGHETSALLI 915
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT 215
+K+ D + I + T + A + +++ L+ KGA + VD++ T
Sbjct: 916 LEKITDRNL-INATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYT 967
Score = 40.3 bits (90), Expect = 0.010
Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 13/169 (7%)
Query: 58 EDLINNELKNNA---NIKLDSGWTPLMHACFHAQDKI-VQYLLEKDADPNLHS-DSVTPI 112
+D++ NEL + N K + G+TPL A + ++ L+ AD N+ S D TP+
Sbjct: 257 QDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPL 316
Query: 113 -MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
M A + + TI I +++ D+ G TPL A G + L+
Sbjct: 317 HMTALHGRFSRSQTI-------IQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 369
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ R HG + A + L+ G + D RT L A
Sbjct: 370 DTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAA 418
Score = 37.5 bits (83), Expect = 0.072
Identities = 37/168 (22%), Positives = 72/168 (42%), Gaps = 9/168 (5%)
Query: 74 DSGWTPLMHACFHAQD-KIVQYLLEKDADPNLHSD---SVTPIMAACSN----SSADNDT 125
+ G TPL +A D K ++YLL DA+P + + AA + ++T
Sbjct: 475 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 534
Query: 126 IYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVF 185
++ + + + +R +PL A G + L+ +++++R+ G T +
Sbjct: 535 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 594
Query: 186 WAVHHNQPEILEMLIEKGARLTEVDK-SNRTLLEIANCHDHQVIIEIL 232
A E +++LI +GA + D RT + A + H + +L
Sbjct: 595 LAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLL 642
Score = 35.9 bits (79), Expect = 0.22
Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
Q L++AI +G + L+ + ++ +D T + A + EI+E+LI GAR+
Sbjct: 15 QPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVN 74
Query: 208 EVDKSNRTLLE--IANCHDHQVIIEILKKSLNLD 239
D T L +A+C + V + +LK S +++
Sbjct: 75 AKDSKWLTPLHRAVASCSEEAVQV-LLKHSADVN 107
Score = 31.5 bits (68), Expect = 4.8
Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW-AVHHN 191
L++ N D++G++PL A ++ L+ ++ D+ G T + + A
Sbjct: 430 LLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDT 489
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
+ LE L+ A DK + + + H++ ++++ LD
Sbjct: 490 DGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLD 537
>BC117367-1|AAI17368.1| 264|Homo sapiens ankyrin repeat domain 19
protein.
Length = 264
Score = 68.9 bits (161), Expect = 3e-11
Identities = 52/197 (26%), Positives = 99/197 (50%), Gaps = 11/197 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKN-NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ A I G+ +VE + ++ +A + D T L C H + ++V LL + N
Sbjct: 38 IHRAAIKGDAAEVEHCLTRRFRDLDARDRKDR--TVLHLTCAHGRVEVVTLLLSRRCQIN 95
Query: 104 LHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
++ + TP+M A + +I+ L++ NI D Y T L A+ + ++
Sbjct: 96 IYDRLNRTPLMKAVHCQ----EEACAII--LLEHGANPNIKDIYSNTALHYAVYNKGTSL 149
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+KLL NIE ++ G T + +A++ + +I+E L++ A L +D RT L +A
Sbjct: 150 AEKLLSHHANIEALNEEGNTPLLFAINSRRQQIVEFLLKNQANLHAIDNFRRTALMLAVQ 209
Query: 223 HDHQVIIE-ILKKSLNL 238
H+ I+ +L++++N+
Sbjct: 210 HNSSSIVSLLLQQNINI 226
Score = 60.5 bits (140), Expect = 9e-09
Identities = 50/191 (26%), Positives = 86/191 (45%), Gaps = 9/191 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K L +G ++ V L++ + N +L+ TPLM A ++ LLE
Sbjct: 66 RKDRTVLHLTCAHGRVEVVTLLLSRRCQINIYDRLNR--TPLMKAVHCQEEACAIILLEH 123
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
A+PN+ S T + A N S+ L+ + + + G TPL+ AI+S
Sbjct: 124 GANPNIKDIYSNTALHYAVYNKGT------SLAEKLLSHHANIEALNEEGNTPLLFAINS 177
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
R + + LL Q N+ D TA+ AV HN I+ +L+++ + D +T
Sbjct: 178 RRQQIVEFLLKNQANLHAIDNFRRTALMLAVQHNSSSIVSLLLQQNINIFSQDLFGQTAE 237
Query: 218 EIANCHDHQVI 228
+ A C++ + I
Sbjct: 238 DYAVCYNFRSI 248
Score = 37.9 bits (84), Expect = 0.055
Identities = 40/130 (30%), Positives = 67/130 (51%), Gaps = 17/130 (13%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDAD 101
AL A+ N E L L ++ANI+ + G TPL+ A + +IV++LL+ A
Sbjct: 137 ALHYAVYNKGTSLAEKL----LSHHANIEALNEEGNTPLLFAINSRRQQIVEFLLKNQA- 191
Query: 102 PNLHS-DSV--TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
NLH+ D+ T +M A ++S+ SIV L+ +N + D +GQT A+
Sbjct: 192 -NLHAIDNFRRTALMLAVQHNSS------SIVSLLLQQNINIFSQDLFGQTAEDYAVCYN 244
Query: 159 RVAVAQKLLD 168
++ Q++L+
Sbjct: 245 FRSIQQQILE 254
>BC038951-1|AAH38951.1| 264|Homo sapiens ANKRD19 protein protein.
Length = 264
Score = 68.9 bits (161), Expect = 3e-11
Identities = 52/197 (26%), Positives = 99/197 (50%), Gaps = 11/197 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKN-NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ A I G+ +VE + ++ +A + D T L C H + ++V LL + N
Sbjct: 38 IHRAAIKGDAAEVEHCLTRRFRDLDARDRKDR--TVLHLTCAHGRVEVVTLLLSRRCQIN 95
Query: 104 LHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
++ + TP+M A + +I+ L++ NI D Y T L A+ + ++
Sbjct: 96 IYDRLNRTPLMKAVHCQ----EEACAII--LLEHGANPNIKDIYSNTALHYAVYNKGTSL 149
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+KLL NIE ++ G T + +A++ + +I+E L++ A L +D RT L +A
Sbjct: 150 AEKLLSHHANIEALNEEGNTPLLFAINSRRQQIVEFLLKNQANLHAIDNFRRTALMLAVQ 209
Query: 223 HDHQVIIE-ILKKSLNL 238
H+ I+ +L++++N+
Sbjct: 210 HNSSSIVSLLLQQNINI 226
Score = 60.5 bits (140), Expect = 9e-09
Identities = 50/191 (26%), Positives = 86/191 (45%), Gaps = 9/191 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K L +G ++ V L++ + N +L+ TPLM A ++ LLE
Sbjct: 66 RKDRTVLHLTCAHGRVEVVTLLLSRRCQINIYDRLNR--TPLMKAVHCQEEACAIILLEH 123
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
A+PN+ S T + A N S+ L+ + + + G TPL+ AI+S
Sbjct: 124 GANPNIKDIYSNTALHYAVYNKGT------SLAEKLLSHHANIEALNEEGNTPLLFAINS 177
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
R + + LL Q N+ D TA+ AV HN I+ +L+++ + D +T
Sbjct: 178 RRQQIVEFLLKNQANLHAIDNFRRTALMLAVQHNSSSIVSLLLQQNINIFSQDLFGQTAE 237
Query: 218 EIANCHDHQVI 228
+ A C++ + I
Sbjct: 238 DYAVCYNFRSI 248
Score = 37.9 bits (84), Expect = 0.055
Identities = 40/130 (30%), Positives = 67/130 (51%), Gaps = 17/130 (13%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDAD 101
AL A+ N E L L ++ANI+ + G TPL+ A + +IV++LL+ A
Sbjct: 137 ALHYAVYNKGTSLAEKL----LSHHANIEALNEEGNTPLLFAINSRRQQIVEFLLKNQA- 191
Query: 102 PNLHS-DSV--TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
NLH+ D+ T +M A ++S+ SIV L+ +N + D +GQT A+
Sbjct: 192 -NLHAIDNFRRTALMLAVQHNSS------SIVSLLLQQNINIFSQDLFGQTAEDYAVCYN 244
Query: 159 RVAVAQKLLD 168
++ Q++L+
Sbjct: 245 FRSIQQQILE 254
>BC028712-1|AAH28712.1| 264|Homo sapiens ANKRD19 protein protein.
Length = 264
Score = 68.9 bits (161), Expect = 3e-11
Identities = 52/197 (26%), Positives = 99/197 (50%), Gaps = 11/197 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKN-NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ A I G+ +VE + ++ +A + D T L C H + ++V LL + N
Sbjct: 38 IHRAAIKGDAAEVEHCLTRRFRDLDARDRKDR--TVLHLTCAHGRVEVVTLLLSRRCQIN 95
Query: 104 LHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
++ + TP+M A + +I+ L++ NI D Y T L A+ + ++
Sbjct: 96 IYDRLNRTPLMKAVHCQ----EEACAII--LLEHGANPNIKDIYSNTALHYAVYNKGTSL 149
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+KLL NIE ++ G T + +A++ + +I+E L++ A L +D RT L +A
Sbjct: 150 AEKLLSHHANIEALNEEGNTPLLFAINSRRQQIVEFLLKNQANLHAIDNFRRTALMLAVQ 209
Query: 223 HDHQVIIE-ILKKSLNL 238
H+ I+ +L++++N+
Sbjct: 210 HNSSSIVSLLLQQNINI 226
Score = 60.5 bits (140), Expect = 9e-09
Identities = 50/191 (26%), Positives = 86/191 (45%), Gaps = 9/191 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K L +G ++ V L++ + N +L+ TPLM A ++ LLE
Sbjct: 66 RKDRTVLHLTCAHGRVEVVTLLLSRRCQINIYDRLNR--TPLMKAVHCQEEACAIILLEH 123
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
A+PN+ S T + A N S+ L+ + + + G TPL+ AI+S
Sbjct: 124 GANPNIKDIYSNTALHYAVYNKGT------SLAEKLLSHHANIEALNEEGNTPLLFAINS 177
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
R + + LL Q N+ D TA+ AV HN I+ +L+++ + D +T
Sbjct: 178 RRQQIVEFLLKNQANLHAIDNFRRTALMLAVQHNSSSIVSLLLQQNINIFSQDLFGQTAE 237
Query: 218 EIANCHDHQVI 228
+ A C++ + I
Sbjct: 238 DYAVCYNFRSI 248
Score = 37.9 bits (84), Expect = 0.055
Identities = 40/130 (30%), Positives = 67/130 (51%), Gaps = 17/130 (13%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDAD 101
AL A+ N E L L ++ANI+ + G TPL+ A + +IV++LL+ A
Sbjct: 137 ALHYAVYNKGTSLAEKL----LSHHANIEALNEEGNTPLLFAINSRRQQIVEFLLKNQA- 191
Query: 102 PNLHS-DSV--TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
NLH+ D+ T +M A ++S+ SIV L+ +N + D +GQT A+
Sbjct: 192 -NLHAIDNFRRTALMLAVQHNSS------SIVSLLLQQNINIFSQDLFGQTAEDYAVCYN 244
Query: 159 RVAVAQKLLD 168
++ Q++L+
Sbjct: 245 FRSIQQQILE 254
>AL136981-3|CAC12726.1| 264|Homo sapiens ankyrin repeat domain 19
protein.
Length = 264
Score = 68.9 bits (161), Expect = 3e-11
Identities = 52/197 (26%), Positives = 99/197 (50%), Gaps = 11/197 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKN-NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ A I G+ +VE + ++ +A + D T L C H + ++V LL + N
Sbjct: 38 IHRAAIKGDAAEVEHCLTRRFRDLDARDRKDR--TVLHLTCAHGRVEVVTLLLSRRCQIN 95
Query: 104 LHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
++ + TP+M A + +I+ L++ NI D Y T L A+ + ++
Sbjct: 96 IYDRLNRTPLMKAVHCQ----EEACAII--LLEHGANPNIKDIYSNTALHYAVYNKGTSL 149
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+KLL NIE ++ G T + +A++ + +I+E L++ A L +D RT L +A
Sbjct: 150 AEKLLSHHANIEALNEEGNTPLLFAINSRRQQIVEFLLKNQANLHAIDNFRRTALMLAVQ 209
Query: 223 HDHQVIIE-ILKKSLNL 238
H+ I+ +L++++N+
Sbjct: 210 HNSSSIVSLLLQQNINI 226
Score = 60.5 bits (140), Expect = 9e-09
Identities = 50/191 (26%), Positives = 86/191 (45%), Gaps = 9/191 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K L +G ++ V L++ + N +L+ TPLM A ++ LLE
Sbjct: 66 RKDRTVLHLTCAHGRVEVVTLLLSRRCQINIYDRLNR--TPLMKAVHCQEEACAIILLEH 123
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
A+PN+ S T + A N S+ L+ + + + G TPL+ AI+S
Sbjct: 124 GANPNIKDIYSNTALHYAVYNKGT------SLAEKLLSHHANIEALNEEGNTPLLFAINS 177
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
R + + LL Q N+ D TA+ AV HN I+ +L+++ + D +T
Sbjct: 178 RRQQIVEFLLKNQANLHAIDNFRRTALMLAVQHNSSSIVSLLLQQNINIFSQDLFGQTAE 237
Query: 218 EIANCHDHQVI 228
+ A C++ + I
Sbjct: 238 DYAVCYNFRSI 248
Score = 37.9 bits (84), Expect = 0.055
Identities = 40/130 (30%), Positives = 67/130 (51%), Gaps = 17/130 (13%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDAD 101
AL A+ N E L L ++ANI+ + G TPL+ A + +IV++LL+ A
Sbjct: 137 ALHYAVYNKGTSLAEKL----LSHHANIEALNEEGNTPLLFAINSRRQQIVEFLLKNQA- 191
Query: 102 PNLHS-DSV--TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
NLH+ D+ T +M A ++S+ SIV L+ +N + D +GQT A+
Sbjct: 192 -NLHAIDNFRRTALMLAVQHNSS------SIVSLLLQQNINIFSQDLFGQTAEDYAVCYN 244
Query: 159 RVAVAQKLLD 168
++ Q++L+
Sbjct: 245 FRSIQQQILE 254
>X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2)
protein.
Length = 1719
Score = 68.1 bits (159), Expect = 4e-11
Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 9/168 (5%)
Query: 37 SKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLL 96
S KVE L A G+ + + L+ N+ K NA K D TPL A +V+ LL
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ--TPLHCAARIGHTNMVKLLL 490
Query: 97 EKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
E +A+PNL + + TP+ A + T+ +++ + C+ + G TPL A
Sbjct: 491 ENNANPNLATTAGHTPLHIAAREGHVE--TVLALLEKEASQACMT----KKGFTPLHVAA 544
Query: 156 SSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
G+V VA+ LL+ + ++G T + AVHHN +I+++L+ +G
Sbjct: 545 KYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Score = 58.8 bits (136), Expect = 3e-08
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L A G++ V++L+ N +N+K++ TPL A ++ +YLL+ A N
Sbjct: 408 LHVASFMGHLPIVKNLLQRGASPNVSNVKVE---TPLHMAARAGHTEVAKYLLQNKAKVN 464
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ D TP+ A + +V L++ N N+ G TPL A G V
Sbjct: 465 AKAKDDQTPLHCAARIGHTN------MVKLLLENNANPNLATTAGHTPLHIAAREGHVET 518
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
LL+ + + + G+T + A + + + E+L+E+ A K+ T L +A
Sbjct: 519 VLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVH 578
Query: 223 HDHQVIIEIL 232
H++ I+++L
Sbjct: 579 HNNLDIVKLL 588
Score = 57.2 bits (132), Expect = 8e-08
Identities = 49/201 (24%), Positives = 94/201 (46%), Gaps = 11/201 (5%)
Query: 37 SKKKVEV-ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
+K KV + AL A N + + L+ N+ N ++ +G+TPL A + + Q L
Sbjct: 168 TKGKVRLPALHIAARNDDTRTAAVLLQND--PNPDVLSKTGFTPLHIAAHYENLNVAQLL 225
Query: 96 LEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L + A N + +TP+ A + +V L+DR + + TPL A
Sbjct: 226 LNRGASVNFTPQNGITPLHIASRRGNV------IMVRLLLDRGAQIETKTKDELTPLHCA 279
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+G V +++ LLD I+ + ++G + + A + + + +L++ A + ++ +
Sbjct: 280 ARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHL 339
Query: 215 TLLEI-ANCHDHQVIIEILKK 234
T L + A+C H+V +L K
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDK 360
Score = 55.6 bits (128), Expect = 3e-07
Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 7/162 (4%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNL 133
+G+TPL A Q ++ + LL+ N S VTP+ A A+ +V L
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAE------MVALL 654
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ + N+G++ G TPL G V VA L+ V ++ + G+T + A H+
Sbjct: 655 LSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNI 714
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
++++ L++ A + K + L A H I+ +L K+
Sbjct: 715 KLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 756
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 7/167 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTI 126
+AN + G TPL A ++V LL K A+ NL + S +TP+
Sbjct: 627 SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHV----- 681
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+ LI +++ R G TPL A G + + + LL Q ++ + + G++ +
Sbjct: 682 -PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQ 740
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
A +I+ +L++ GA EV T L IA + + ++LK
Sbjct: 741 AAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 787
Score = 53.2 bits (122), Expect = 1e-06
Identities = 47/198 (23%), Positives = 89/198 (44%), Gaps = 13/198 (6%)
Query: 36 SSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
++ KK AL A + G + V +L+N N N + G+TPL A ++V++L
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGA--NVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 96 LEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
LE A+ N+ + D TP+ A ++V +LI+ + L A
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHE------NVVAHLIN----YGTKGKVRLPALHIA 180
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+ A LL N ++ + G+T + A H+ + ++L+ +GA + ++
Sbjct: 181 ARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGI 240
Query: 215 TLLEIANCHDHQVIIEIL 232
T L IA+ + +++ +L
Sbjct: 241 TPLHIASRRGNVIMVRLL 258
Score = 49.6 bits (113), Expect = 2e-05
Identities = 26/101 (25%), Positives = 50/101 (49%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ + IL + G T L A +G+ V ++L++ N+ + Q G+T ++ A
Sbjct: 60 MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAA 119
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVII 229
N E+++ L+E GA + T L +A H+ ++
Sbjct: 120 QENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVV 160
Score = 48.0 bits (109), Expect = 5e-05
Identities = 52/206 (25%), Positives = 89/206 (43%), Gaps = 19/206 (9%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ V LIN K + P +H D + LL+ D +P+
Sbjct: 148 LAVALQQGHENVVAHLINYGTKGKVRL-------PALHIAARNDDTRTAAVLLQNDPNPD 200
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ S + TP+ A + +N + + L++R +N + G TPL A G V +
Sbjct: 201 VLSKTGFTPLHIA---AHYENLNVAQL---LLNRGASVNFTPQNGITPLHIASRRGNVIM 254
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LLD IE + + T + A + I E+L++ GA + K+ + + +A
Sbjct: 255 VRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQ 314
Query: 223 HDHQVIIE-ILKKSLNLDD---DHKT 244
DH + +L+ +DD DH T
Sbjct: 315 GDHLDCVRLLLQYDAEIDDITLDHLT 340
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/84 (32%), Positives = 42/84 (50%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A G VA+ LLD R +G+T + A N ++E+L++ GA +
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Query: 209 VDKSNRTLLEIANCHDHQVIIEIL 232
V +S T L +A+ H I++ L
Sbjct: 400 VTESGLTPLHVASFMGHLPIVKNL 423
Score = 41.5 bits (93), Expect = 0.004
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 11/220 (5%)
Query: 30 DYSSQISSKKKVEVA-LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQ 88
D +QI +K K E+ L A NG+++ E L+++ A K +G +P+ A
Sbjct: 260 DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTK--NGLSPIHMAAQGDH 317
Query: 89 DKIVQYLLEKDAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYG 147
V+ LL+ DA+ ++ D +TP+ A + + L+D+ N G
Sbjct: 318 LDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGH------HRVAKVLLDKGAKPNSRALNG 371
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
TPL A V V + LL +I+ + G T + A I++ L+++GA
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 431
Query: 208 EVDKSNRTLLEIANCHDH-QVIIEILKKSLNLDDDHKTDE 246
+ T L +A H +V +L+ ++ K D+
Sbjct: 432 VSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ 471
Score = 41.1 bits (92), Expect = 0.006
Identities = 39/169 (23%), Positives = 69/169 (40%), Gaps = 7/169 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTI 126
+ N +G TPL A +V+ LL++ A + D +TP+ A N I
Sbjct: 231 SVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEI 290
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
L+D + + G +P+ A + + LL I+ T +
Sbjct: 291 ------LLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHV 344
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
A H + ++L++KGA+ + T L IA +H ++E+L K+
Sbjct: 345 AAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 393
Score = 39.5 bits (88), Expect = 0.018
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVT 110
GN+K V+ L+ ++ NA KL G++PL A IV LL+ A PN + SD T
Sbjct: 712 GNIKLVKFLLQHQADVNAKTKL--GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 111 PIMAA 115
P+ A
Sbjct: 770 PLAIA 774
>X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for
ankyrin (variant 2.1). ).
Length = 1881
Score = 68.1 bits (159), Expect = 4e-11
Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 9/168 (5%)
Query: 37 SKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLL 96
S KVE L A G+ + + L+ N+ K NA K D TPL A +V+ LL
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ--TPLHCAARIGHTNMVKLLL 490
Query: 97 EKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
E +A+PNL + + TP+ A + T+ +++ + C+ + G TPL A
Sbjct: 491 ENNANPNLATTAGHTPLHIAAREGHVE--TVLALLEKEASQACMT----KKGFTPLHVAA 544
Query: 156 SSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
G+V VA+ LL+ + ++G T + AVHHN +I+++L+ +G
Sbjct: 545 KYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Score = 58.8 bits (136), Expect = 3e-08
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L A G++ V++L+ N +N+K++ TPL A ++ +YLL+ A N
Sbjct: 408 LHVASFMGHLPIVKNLLQRGASPNVSNVKVE---TPLHMAARAGHTEVAKYLLQNKAKVN 464
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ D TP+ A + +V L++ N N+ G TPL A G V
Sbjct: 465 AKAKDDQTPLHCAARIGHTN------MVKLLLENNANPNLATTAGHTPLHIAAREGHVET 518
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
LL+ + + + G+T + A + + + E+L+E+ A K+ T L +A
Sbjct: 519 VLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVH 578
Query: 223 HDHQVIIEIL 232
H++ I+++L
Sbjct: 579 HNNLDIVKLL 588
Score = 57.2 bits (132), Expect = 8e-08
Identities = 49/201 (24%), Positives = 94/201 (46%), Gaps = 11/201 (5%)
Query: 37 SKKKVEV-ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
+K KV + AL A N + + L+ N+ N ++ +G+TPL A + + Q L
Sbjct: 168 TKGKVRLPALHIAARNDDTRTAAVLLQND--PNPDVLSKTGFTPLHIAAHYENLNVAQLL 225
Query: 96 LEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L + A N + +TP+ A + +V L+DR + + TPL A
Sbjct: 226 LNRGASVNFTPQNGITPLHIASRRGNV------IMVRLLLDRGAQIETKTKDELTPLHCA 279
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+G V +++ LLD I+ + ++G + + A + + + +L++ A + ++ +
Sbjct: 280 ARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHL 339
Query: 215 TLLEI-ANCHDHQVIIEILKK 234
T L + A+C H+V +L K
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDK 360
Score = 55.6 bits (128), Expect = 3e-07
Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 7/162 (4%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNL 133
+G+TPL A Q ++ + LL+ N S VTP+ A A+ +V L
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAE------MVALL 654
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ + N+G++ G TPL G V VA L+ V ++ + G+T + A H+
Sbjct: 655 LSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNI 714
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
++++ L++ A + K + L A H I+ +L K+
Sbjct: 715 KLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 756
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 7/167 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTI 126
+AN + G TPL A ++V LL K A+ NL + S +TP+
Sbjct: 627 SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHV----- 681
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+ LI +++ R G TPL A G + + + LL Q ++ + + G++ +
Sbjct: 682 -PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQ 740
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
A +I+ +L++ GA EV T L IA + + ++LK
Sbjct: 741 AAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 787
Score = 53.2 bits (122), Expect = 1e-06
Identities = 47/198 (23%), Positives = 89/198 (44%), Gaps = 13/198 (6%)
Query: 36 SSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
++ KK AL A + G + V +L+N N N + G+TPL A ++V++L
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGA--NVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 96 LEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
LE A+ N+ + D TP+ A ++V +LI+ + L A
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHE------NVVAHLIN----YGTKGKVRLPALHIA 180
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+ A LL N ++ + G+T + A H+ + ++L+ +GA + ++
Sbjct: 181 ARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGI 240
Query: 215 TLLEIANCHDHQVIIEIL 232
T L IA+ + +++ +L
Sbjct: 241 TPLHIASRRGNVIMVRLL 258
Score = 49.6 bits (113), Expect = 2e-05
Identities = 26/101 (25%), Positives = 50/101 (49%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ + IL + G T L A +G+ V ++L++ N+ + Q G+T ++ A
Sbjct: 60 MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAA 119
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVII 229
N E+++ L+E GA + T L +A H+ ++
Sbjct: 120 QENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVV 160
Score = 48.0 bits (109), Expect = 5e-05
Identities = 52/206 (25%), Positives = 89/206 (43%), Gaps = 19/206 (9%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ V LIN K + P +H D + LL+ D +P+
Sbjct: 148 LAVALQQGHENVVAHLINYGTKGKVRL-------PALHIAARNDDTRTAAVLLQNDPNPD 200
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ S + TP+ A + +N + + L++R +N + G TPL A G V +
Sbjct: 201 VLSKTGFTPLHIA---AHYENLNVAQL---LLNRGASVNFTPQNGITPLHIASRRGNVIM 254
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LLD IE + + T + A + I E+L++ GA + K+ + + +A
Sbjct: 255 VRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQ 314
Query: 223 HDHQVIIE-ILKKSLNLDD---DHKT 244
DH + +L+ +DD DH T
Sbjct: 315 GDHLDCVRLLLQYDAEIDDITLDHLT 340
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/84 (32%), Positives = 42/84 (50%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A G VA+ LLD R +G+T + A N ++E+L++ GA +
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Query: 209 VDKSNRTLLEIANCHDHQVIIEIL 232
V +S T L +A+ H I++ L
Sbjct: 400 VTESGLTPLHVASFMGHLPIVKNL 423
Score = 41.5 bits (93), Expect = 0.004
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 11/220 (5%)
Query: 30 DYSSQISSKKKVEVA-LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQ 88
D +QI +K K E+ L A NG+++ E L+++ A K +G +P+ A
Sbjct: 260 DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTK--NGLSPIHMAAQGDH 317
Query: 89 DKIVQYLLEKDAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYG 147
V+ LL+ DA+ ++ D +TP+ A + + L+D+ N G
Sbjct: 318 LDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGH------HRVAKVLLDKGAKPNSRALNG 371
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
TPL A V V + LL +I+ + G T + A I++ L+++GA
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 431
Query: 208 EVDKSNRTLLEIANCHDH-QVIIEILKKSLNLDDDHKTDE 246
+ T L +A H +V +L+ ++ K D+
Sbjct: 432 VSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ 471
Score = 41.1 bits (92), Expect = 0.006
Identities = 39/169 (23%), Positives = 69/169 (40%), Gaps = 7/169 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTI 126
+ N +G TPL A +V+ LL++ A + D +TP+ A N I
Sbjct: 231 SVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEI 290
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
L+D + + G +P+ A + + LL I+ T +
Sbjct: 291 ------LLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHV 344
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
A H + ++L++KGA+ + T L IA +H ++E+L K+
Sbjct: 345 AAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 393
Score = 39.5 bits (88), Expect = 0.018
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVT 110
GN+K V+ L+ ++ NA KL G++PL A IV LL+ A PN + SD T
Sbjct: 712 GNIKLVKFLLQHQADVNAKTKL--GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 111 PIMAA 115
P+ A
Sbjct: 770 PLAIA 774
>U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein.
Length = 1856
Score = 68.1 bits (159), Expect = 4e-11
Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 9/168 (5%)
Query: 37 SKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLL 96
S KVE L A G+ + + L+ N+ K NA K D TPL A +V+ LL
Sbjct: 400 SNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ--TPLHCAARIGHTNMVKLLL 457
Query: 97 EKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
E +A+PNL + + TP+ A + T+ +++ + C+ + G TPL A
Sbjct: 458 ENNANPNLATTAGHTPLHIAAREGHVE--TVLALLEKEASQACMT----KKGFTPLHVAA 511
Query: 156 SSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
G+V VA+ LL+ + ++G T + AVHHN +I+++L+ +G
Sbjct: 512 KYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 559
Score = 58.8 bits (136), Expect = 3e-08
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L A G++ V++L+ N +N+K++ TPL A ++ +YLL+ A N
Sbjct: 375 LHVASFMGHLPIVKNLLQRGASPNVSNVKVE---TPLHMAARAGHTEVAKYLLQNKAKVN 431
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ D TP+ A + +V L++ N N+ G TPL A G V
Sbjct: 432 AKAKDDQTPLHCAARIGHTN------MVKLLLENNANPNLATTAGHTPLHIAAREGHVET 485
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
LL+ + + + G+T + A + + + E+L+E+ A K+ T L +A
Sbjct: 486 VLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVH 545
Query: 223 HDHQVIIEIL 232
H++ I+++L
Sbjct: 546 HNNLDIVKLL 555
Score = 57.2 bits (132), Expect = 8e-08
Identities = 49/201 (24%), Positives = 94/201 (46%), Gaps = 11/201 (5%)
Query: 37 SKKKVEV-ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
+K KV + AL A N + + L+ N+ N ++ +G+TPL A + + Q L
Sbjct: 135 TKGKVRLPALHIAARNDDTRTAAVLLQND--PNPDVLSKTGFTPLHIAAHYENLNVAQLL 192
Query: 96 LEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L + A N + +TP+ A + +V L+DR + + TPL A
Sbjct: 193 LNRGASVNFTPQNGITPLHIASRRGNV------IMVRLLLDRGAQIETKTKDELTPLHCA 246
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+G V +++ LLD I+ + ++G + + A + + + +L++ A + ++ +
Sbjct: 247 ARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHL 306
Query: 215 TLLEI-ANCHDHQVIIEILKK 234
T L + A+C H+V +L K
Sbjct: 307 TPLHVAAHCGHHRVAKVLLDK 327
Score = 55.6 bits (128), Expect = 3e-07
Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 7/162 (4%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNL 133
+G+TPL A Q ++ + LL+ N S VTP+ A A+ +V L
Sbjct: 568 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAE------MVALL 621
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ + N+G++ G TPL G V VA L+ V ++ + G+T + A H+
Sbjct: 622 LSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNI 681
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
++++ L++ A + K + L A H I+ +L K+
Sbjct: 682 KLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 723
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 7/167 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTI 126
+AN + G TPL A ++V LL K A+ NL + S +TP+
Sbjct: 594 SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHV----- 648
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+ LI +++ R G TPL A G + + + LL Q ++ + + G++ +
Sbjct: 649 -PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQ 707
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
A +I+ +L++ GA EV T L IA + + ++LK
Sbjct: 708 AAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 754
Score = 51.2 bits (117), Expect = 6e-06
Identities = 46/195 (23%), Positives = 87/195 (44%), Gaps = 13/195 (6%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K AL A + G + V +L+N N N + G+TPL A ++V++LLE
Sbjct: 43 QKGNTALHIAALAGQDEVVRELVNYGA--NVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 100
Query: 99 DADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
A+ N+ + D TP+ A ++V +LI+ + L A +
Sbjct: 101 GANQNVATEDGFTPLAVALQQGHE------NVVAHLIN----YGTKGKVRLPALHIAARN 150
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
A LL N ++ + G+T + A H+ + ++L+ +GA + ++ T L
Sbjct: 151 DDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPL 210
Query: 218 EIANCHDHQVIIEIL 232
IA+ + +++ +L
Sbjct: 211 HIASRRGNVIMVRLL 225
Score = 48.0 bits (109), Expect = 5e-05
Identities = 52/206 (25%), Positives = 89/206 (43%), Gaps = 19/206 (9%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ V LIN K + P +H D + LL+ D +P+
Sbjct: 115 LAVALQQGHENVVAHLINYGTKGKVRL-------PALHIAARNDDTRTAAVLLQNDPNPD 167
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ S + TP+ A + +N + + L++R +N + G TPL A G V +
Sbjct: 168 VLSKTGFTPLHIA---AHYENLNVAQL---LLNRGASVNFTPQNGITPLHIASRRGNVIM 221
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LLD IE + + T + A + I E+L++ GA + K+ + + +A
Sbjct: 222 VRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQ 281
Query: 223 HDHQVIIE-ILKKSLNLDD---DHKT 244
DH + +L+ +DD DH T
Sbjct: 282 GDHLDCVRLLLQYDAEIDDITLDHLT 307
Score = 45.6 bits (103), Expect = 3e-04
Identities = 23/90 (25%), Positives = 46/90 (51%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+N ++ G T L A +G+ V ++L++ N+ + Q G+T ++ A N E+++ L
Sbjct: 38 INTCNQKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 97
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDHQVII 229
+E GA + T L +A H+ ++
Sbjct: 98 LENGANQNVATEDGFTPLAVALQQGHENVV 127
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/84 (32%), Positives = 42/84 (50%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A G VA+ LLD R +G+T + A N ++E+L++ GA +
Sbjct: 307 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 366
Query: 209 VDKSNRTLLEIANCHDHQVIIEIL 232
V +S T L +A+ H I++ L
Sbjct: 367 VTESGLTPLHVASFMGHLPIVKNL 390
Score = 41.5 bits (93), Expect = 0.004
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 11/220 (5%)
Query: 30 DYSSQISSKKKVEVA-LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQ 88
D +QI +K K E+ L A NG+++ E L+++ A K +G +P+ A
Sbjct: 227 DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTK--NGLSPIHMAAQGDH 284
Query: 89 DKIVQYLLEKDAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYG 147
V+ LL+ DA+ ++ D +TP+ A + + L+D+ N G
Sbjct: 285 LDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGH------HRVAKVLLDKGAKPNSRALNG 338
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
TPL A V V + LL +I+ + G T + A I++ L+++GA
Sbjct: 339 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 398
Query: 208 EVDKSNRTLLEIANCHDH-QVIIEILKKSLNLDDDHKTDE 246
+ T L +A H +V +L+ ++ K D+
Sbjct: 399 VSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ 438
Score = 41.1 bits (92), Expect = 0.006
Identities = 39/169 (23%), Positives = 69/169 (40%), Gaps = 7/169 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTI 126
+ N +G TPL A +V+ LL++ A + D +TP+ A N I
Sbjct: 198 SVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEI 257
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
L+D + + G +P+ A + + LL I+ T +
Sbjct: 258 ------LLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHV 311
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
A H + ++L++KGA+ + T L IA +H ++E+L K+
Sbjct: 312 AAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 360
Score = 39.5 bits (88), Expect = 0.018
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVT 110
GN+K V+ L+ ++ NA KL G++PL A IV LL+ A PN + SD T
Sbjct: 679 GNIKLVKFLLQHQADVNAKTKL--GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 736
Query: 111 PIMAA 115
P+ A
Sbjct: 737 PLAIA 741
>M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein.
Length = 1880
Score = 68.1 bits (159), Expect = 4e-11
Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 9/168 (5%)
Query: 37 SKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLL 96
S KVE L A G+ + + L+ N+ K NA K D TPL A +V+ LL
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ--TPLHCAARIGHTNMVKLLL 490
Query: 97 EKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
E +A+PNL + + TP+ A + T+ +++ + C+ + G TPL A
Sbjct: 491 ENNANPNLATTAGHTPLHIAAREGHVE--TVLALLEKEASQACMT----KKGFTPLHVAA 544
Query: 156 SSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
G+V VA+ LL+ + ++G T + AVHHN +I+++L+ +G
Sbjct: 545 KYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Score = 58.8 bits (136), Expect = 3e-08
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L A G++ V++L+ N +N+K++ TPL A ++ +YLL+ A N
Sbjct: 408 LHVASFMGHLPIVKNLLQRGASPNVSNVKVE---TPLHMAARAGHTEVAKYLLQNKAKVN 464
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ D TP+ A + +V L++ N N+ G TPL A G V
Sbjct: 465 AKAKDDQTPLHCAARIGHTN------MVKLLLENNANPNLATTAGHTPLHIAAREGHVET 518
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
LL+ + + + G+T + A + + + E+L+E+ A K+ T L +A
Sbjct: 519 VLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVH 578
Query: 223 HDHQVIIEIL 232
H++ I+++L
Sbjct: 579 HNNLDIVKLL 588
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/201 (23%), Positives = 94/201 (46%), Gaps = 11/201 (5%)
Query: 37 SKKKVEV-ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
+K KV + AL A N + + L+ N+ N ++ +G+TPL A + + Q L
Sbjct: 168 TKGKVRLPALHIAARNDDTRTAAVLLQND--PNPDVLSKTGFTPLHIAAHYENLNVAQLL 225
Query: 96 LEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L + + N + +TP+ A + +V L+DR + + TPL A
Sbjct: 226 LNRGSSVNFTPQNGITPLHIASRRGNV------IMVRLLLDRGAQIETKTKDELTPLHCA 279
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+G V +++ LLD I+ + ++G + + A + + + +L++ A + ++ +
Sbjct: 280 ARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHL 339
Query: 215 TLLEI-ANCHDHQVIIEILKK 234
T L + A+C H+V +L K
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDK 360
Score = 55.6 bits (128), Expect = 3e-07
Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 7/162 (4%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNL 133
+G+TPL A Q ++ + LL+ N S VTP+ A A+ +V L
Sbjct: 601 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAE------MVALL 654
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ + N+G++ G TPL G V VA L+ V ++ + G+T + A H+
Sbjct: 655 LSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNI 714
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
++++ L++ A + K + L A H I+ +L K+
Sbjct: 715 KLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 756
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 7/167 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTI 126
+AN + G TPL A ++V LL K A+ NL + S +TP+
Sbjct: 627 SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHV----- 681
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+ LI +++ R G TPL A G + + + LL Q ++ + + G++ +
Sbjct: 682 -PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQ 740
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
A +I+ +L++ GA EV T L IA + + ++LK
Sbjct: 741 AAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 787
Score = 52.0 bits (119), Expect = 3e-06
Identities = 46/198 (23%), Positives = 89/198 (44%), Gaps = 13/198 (6%)
Query: 36 SSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
++ KK AL A + G + V +L+N N N + G+TPL A ++V++L
Sbjct: 73 TTTKKGNTALHIAALAGQDEVVRELVNYGA--NVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 96 LEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
LE A+ N+ + D TP+ A ++V +LI+ + L A
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHE------NVVAHLIN----YGTKGKVRLPALHIA 180
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+ A LL N ++ + G+T + A H+ + ++L+ +G+ + ++
Sbjct: 181 ARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGI 240
Query: 215 TLLEIANCHDHQVIIEIL 232
T L IA+ + +++ +L
Sbjct: 241 TPLHIASRRGNVIMVRLL 258
Score = 49.6 bits (113), Expect = 2e-05
Identities = 26/101 (25%), Positives = 50/101 (49%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ + IL + G T L A +G+ V ++L++ N+ + Q G+T ++ A
Sbjct: 60 MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAA 119
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVII 229
N E+++ L+E GA + T L +A H+ ++
Sbjct: 120 QENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVV 160
Score = 47.6 bits (108), Expect = 7e-05
Identities = 52/206 (25%), Positives = 89/206 (43%), Gaps = 19/206 (9%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ V LIN K + P +H D + LL+ D +P+
Sbjct: 148 LAVALQQGHENVVAHLINYGTKGKVRL-------PALHIAARNDDTRTAAVLLQNDPNPD 200
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ S + TP+ A + +N + + L++R +N + G TPL A G V +
Sbjct: 201 VLSKTGFTPLHIA---AHYENLNVAQL---LLNRGSSVNFTPQNGITPLHIASRRGNVIM 254
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LLD IE + + T + A + I E+L++ GA + K+ + + +A
Sbjct: 255 VRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQ 314
Query: 223 HDHQVIIE-ILKKSLNLDD---DHKT 244
DH + +L+ +DD DH T
Sbjct: 315 GDHLDCVRLLLQYDAEIDDITLDHLT 340
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/84 (32%), Positives = 42/84 (50%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A G VA+ LLD R +G+T + A N ++E+L++ GA +
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Query: 209 VDKSNRTLLEIANCHDHQVIIEIL 232
V +S T L +A+ H I++ L
Sbjct: 400 VTESGLTPLHVASFMGHLPIVKNL 423
Score = 41.5 bits (93), Expect = 0.004
Identities = 39/170 (22%), Positives = 70/170 (41%), Gaps = 7/170 (4%)
Query: 67 NNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDT 125
++ N +G TPL A +V+ LL++ A + D +TP+ A N
Sbjct: 230 SSVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISE 289
Query: 126 IYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVF 185
I L+D + + G +P+ A + + LL I+ T +
Sbjct: 290 I------LLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLH 343
Query: 186 WAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
A H + ++L++KGA+ + T L IA +H ++E+L K+
Sbjct: 344 VAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 393
Score = 41.5 bits (93), Expect = 0.004
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 11/220 (5%)
Query: 30 DYSSQISSKKKVEVA-LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQ 88
D +QI +K K E+ L A NG+++ E L+++ A K +G +P+ A
Sbjct: 260 DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTK--NGLSPIHMAAQGDH 317
Query: 89 DKIVQYLLEKDAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYG 147
V+ LL+ DA+ ++ D +TP+ A + + L+D+ N G
Sbjct: 318 LDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGH------HRVAKVLLDKGAKPNSRALNG 371
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
TPL A V V + LL +I+ + G T + A I++ L+++GA
Sbjct: 372 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 431
Query: 208 EVDKSNRTLLEIANCHDH-QVIIEILKKSLNLDDDHKTDE 246
+ T L +A H +V +L+ ++ K D+
Sbjct: 432 VSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ 471
Score = 39.5 bits (88), Expect = 0.018
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVT 110
GN+K V+ L+ ++ NA KL G++PL A IV LL+ A PN + SD T
Sbjct: 712 GNIKLVKFLLQHQADVNAKTKL--GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 111 PIMAA 115
P+ A
Sbjct: 770 PLAIA 774
>AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4
variant protein.
Length = 1899
Score = 68.1 bits (159), Expect = 4e-11
Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 9/168 (5%)
Query: 37 SKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLL 96
S KVE L A G+ + + L+ N+ K NA K D TPL A +V+ LL
Sbjct: 468 SNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ--TPLHCAARIGHTNMVKLLL 525
Query: 97 EKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
E +A+PNL + + TP+ A + T+ +++ + C+ + G TPL A
Sbjct: 526 ENNANPNLATTAGHTPLHIAAREGHVE--TVLALLEKEASQACMT----KKGFTPLHVAA 579
Query: 156 SSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
G+V VA+ LL+ + ++G T + AVHHN +I+++L+ +G
Sbjct: 580 KYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRG 627
Score = 58.8 bits (136), Expect = 3e-08
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L A G++ V++L+ N +N+K++ TPL A ++ +YLL+ A N
Sbjct: 443 LHVASFMGHLPIVKNLLQRGASPNVSNVKVE---TPLHMAARAGHTEVAKYLLQNKAKVN 499
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ D TP+ A + +V L++ N N+ G TPL A G V
Sbjct: 500 AKAKDDQTPLHCAARIGHTN------MVKLLLENNANPNLATTAGHTPLHIAAREGHVET 553
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
LL+ + + + G+T + A + + + E+L+E+ A K+ T L +A
Sbjct: 554 VLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVH 613
Query: 223 HDHQVIIEIL 232
H++ I+++L
Sbjct: 614 HNNLDIVKLL 623
Score = 57.2 bits (132), Expect = 8e-08
Identities = 49/201 (24%), Positives = 94/201 (46%), Gaps = 11/201 (5%)
Query: 37 SKKKVEV-ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
+K KV + AL A N + + L+ N+ N ++ +G+TPL A + + Q L
Sbjct: 203 TKGKVRLPALHIAARNDDTRTAAVLLQND--PNPDVLSKTGFTPLHIAAHYENLNVAQLL 260
Query: 96 LEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L + A N + +TP+ A + +V L+DR + + TPL A
Sbjct: 261 LNRGASVNFTPQNGITPLHIASRRGNV------IMVRLLLDRGAQIETKTKDELTPLHCA 314
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+G V +++ LLD I+ + ++G + + A + + + +L++ A + ++ +
Sbjct: 315 ARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHL 374
Query: 215 TLLEI-ANCHDHQVIIEILKK 234
T L + A+C H+V +L K
Sbjct: 375 TPLHVAAHCGHHRVAKVLLDK 395
Score = 55.6 bits (128), Expect = 3e-07
Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 7/162 (4%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNL 133
+G+TPL A Q ++ + LL+ N S VTP+ A A+ +V L
Sbjct: 636 NGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAE------MVALL 689
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ + N+G++ G TPL G V VA L+ V ++ + G+T + A H+
Sbjct: 690 LSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNI 749
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
++++ L++ A + K + L A H I+ +L K+
Sbjct: 750 KLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKN 791
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 7/167 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTI 126
+AN + G TPL A ++V LL K A+ NL + S +TP+
Sbjct: 662 SANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHV----- 716
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+ LI +++ R G TPL A G + + + LL Q ++ + + G++ +
Sbjct: 717 -PVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQ 775
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
A +I+ +L++ GA EV T L IA + + ++LK
Sbjct: 776 AAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 822
Score = 49.6 bits (113), Expect = 2e-05
Identities = 26/101 (25%), Positives = 50/101 (49%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ + IL + G T L A +G+ V ++L++ N+ + Q G+T ++ A
Sbjct: 95 MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAA 154
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVII 229
N E+++ L+E GA + T L +A H+ ++
Sbjct: 155 QENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVV 195
Score = 48.0 bits (109), Expect = 5e-05
Identities = 52/206 (25%), Positives = 89/206 (43%), Gaps = 19/206 (9%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ V LIN K + P +H D + LL+ D +P+
Sbjct: 183 LAVALQQGHENVVAHLINYGTKGKVRL-------PALHIAARNDDTRTAAVLLQNDPNPD 235
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ S + TP+ A + +N + + L++R +N + G TPL A G V +
Sbjct: 236 VLSKTGFTPLHIA---AHYENLNVAQL---LLNRGASVNFTPQNGITPLHIASRRGNVIM 289
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LLD IE + + T + A + I E+L++ GA + K+ + + +A
Sbjct: 290 VRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQ 349
Query: 223 HDHQVIIE-ILKKSLNLDD---DHKT 244
DH + +L+ +DD DH T
Sbjct: 350 GDHLDCVRLLLQYDAEIDDITLDHLT 375
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/84 (32%), Positives = 42/84 (50%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A G VA+ LLD R +G+T + A N ++E+L++ GA +
Sbjct: 375 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 434
Query: 209 VDKSNRTLLEIANCHDHQVIIEIL 232
V +S T L +A+ H I++ L
Sbjct: 435 VTESGLTPLHVASFMGHLPIVKNL 458
Score = 41.5 bits (93), Expect = 0.004
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 11/220 (5%)
Query: 30 DYSSQISSKKKVEVA-LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQ 88
D +QI +K K E+ L A NG+++ E L+++ A K +G +P+ A
Sbjct: 295 DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTK--NGLSPIHMAAQGDH 352
Query: 89 DKIVQYLLEKDAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYG 147
V+ LL+ DA+ ++ D +TP+ A + + L+D+ N G
Sbjct: 353 LDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGH------HRVAKVLLDKGAKPNSRALNG 406
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
TPL A V V + LL +I+ + G T + A I++ L+++GA
Sbjct: 407 FTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPN 466
Query: 208 EVDKSNRTLLEIANCHDH-QVIIEILKKSLNLDDDHKTDE 246
+ T L +A H +V +L+ ++ K D+
Sbjct: 467 VSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ 506
Score = 41.1 bits (92), Expect = 0.006
Identities = 39/169 (23%), Positives = 69/169 (40%), Gaps = 7/169 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTI 126
+ N +G TPL A +V+ LL++ A + D +TP+ A N I
Sbjct: 266 SVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEI 325
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
L+D + + G +P+ A + + LL I+ T +
Sbjct: 326 ------LLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHV 379
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
A H + ++L++KGA+ + T L IA +H ++E+L K+
Sbjct: 380 AAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKT 428
Score = 39.5 bits (88), Expect = 0.018
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVT 110
GN+K V+ L+ ++ NA KL G++PL A IV LL+ A PN + SD T
Sbjct: 747 GNIKLVKFLLQHQADVNAKTKL--GYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 804
Query: 111 PIMAA 115
P+ A
Sbjct: 805 PLAIA 809
Score = 31.9 bits (69), Expect = 3.6
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 9/170 (5%)
Query: 38 KKKVEVALQ--EAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
KKK + A A +GN+ D + N + + N +G L A K+V L
Sbjct: 42 KKKADAATSFLRAARSGNLDKALDHLRNGV--DINTCNQNGLNGLHLASKEGHVKMVVEL 99
Query: 96 LEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAI 155
L K+ + + + + D +V L++ +N + G TPL A
Sbjct: 100 LHKEIILETTTKKGNTALHIAALAGQDE-----VVRELVNYGANVNAQSQKGFTPLYMAA 154
Query: 156 SSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGAR 205
+ V + LL+ N + + G+T + A+ ++ LI G +
Sbjct: 155 QENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTK 204
>AY462872-1|AAS58866.1| 394|Homo sapiens POTE2B protein.
Length = 394
Score = 67.7 bits (158), Expect = 6e-11
Identities = 51/187 (27%), Positives = 89/187 (47%), Gaps = 6/187 (3%)
Query: 58 EDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAAC 116
+DLI + N K T L A + ++V+ LL++ N L + T ++ C
Sbjct: 155 KDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVC 214
Query: 117 SNSSADNDTIY----SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVN 172
S+ ++ + L++ NI D YG T L AI + +A+ LL +
Sbjct: 215 SSQLYQHEAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGAD 274
Query: 173 IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
IE +++HG T + VH + ++++ LI+K A L +D+ RT L +A C I+ +L
Sbjct: 275 IESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLL 334
Query: 233 KKSLNLD 239
+ N+D
Sbjct: 335 LEQ-NID 340
Score = 54.8 bits (126), Expect = 4e-07
Identities = 56/223 (25%), Positives = 97/223 (43%), Gaps = 20/223 (8%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNEL--------KNNANIKLDSGWTPLMHACFHAQDK 90
K+ AL A NGN + V+ L++ K A IK+ S A +D+
Sbjct: 171 KQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKVCSSQLYQHEAVQCQEDE 230
Query: 91 IVQYLLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
LLE DPN+ + T + A N D + + L + + +++G T
Sbjct: 231 CALMLLEHGTDPNIPDEYGNTTLHYAIYNE----DKLMAKALLLYGAD--IESKNKHGLT 284
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL+ + + V + L+ + N+ D++G TA+ AV I+ +L+E+ ++
Sbjct: 285 PLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQ 344
Query: 210 DKSNRTLLEIANCHDHQVIIEIL-----KKSLNLDDDHKTDEN 247
D S +T E A H VI ++L K+ L + ++ EN
Sbjct: 345 DLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEN 387
>AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein
protein.
Length = 520
Score = 67.3 bits (157), Expect = 8e-11
Identities = 56/207 (27%), Positives = 103/207 (49%), Gaps = 10/207 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A +G+ + +E L+ + L + +++ SG TPL A F + V L+ + A L
Sbjct: 21 LHLAAYHGHHQALEVLVQSLL--DLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI-L 77
Query: 105 HSDSV---TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
D + TPI AA +N ++ + ++ N +N + +I D GQTPLM ++ +G
Sbjct: 78 VKDYILKRTPIHAAATNGHSE--CLRLLIGNAEPQNAV-DIQDGNGQTPLMLSVLNGHTD 134
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI-A 220
LL+ N++ +D+ G TA+ E ++ L++ GA+ D RT + + A
Sbjct: 135 CVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSA 194
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDEN 247
C V+ +L+ + ++D + T +N
Sbjct: 195 ACGHIGVLGALLQSAASMDANPATADN 221
Score = 64.5 bits (150), Expect = 6e-10
Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 6/161 (3%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLID 135
G+T L AC++ + V+ LLE++ ++ +P+ A N DN+ ++ + +
Sbjct: 223 GYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVIN---DNEGAAEMLIDTLG 279
Query: 136 RNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
+ I+N D G+TPL A + V Q LL + D G T + A + Q
Sbjct: 280 AS-IVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNT 338
Query: 196 LEMLIEK-GARLTEVDKSNRTLLEIANCHDHQV-IIEILKK 234
+EML+ A LT D S T L +A H+ + IL+K
Sbjct: 339 VEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEK 379
Score = 51.6 bits (118), Expect = 4e-06
Identities = 50/206 (24%), Positives = 93/206 (45%), Gaps = 11/206 (5%)
Query: 45 LQEAIINGNMKDVEDLINN-ELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ A NG+ + + LI N E +N +I+ +G TPLM + + V LL K A+ +
Sbjct: 88 IHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVD 147
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
D + + + +++ + C+L D G+TP+ + + G + V
Sbjct: 148 A-KDKWGRTALHRGAVTGHEECVDALLQH--GAKCLLR--DSRGRTPIHLSAACGHIGVL 202
Query: 164 QKLLD----MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
LL M N D HG+TA+ WA ++ +E+L+E+ + + + + L
Sbjct: 203 GALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEV-FQKTEGNAFSPLHC 261
Query: 220 ANCHDHQVIIEILKKSLNLDDDHKTD 245
A +D++ E+L +L + TD
Sbjct: 262 AVINDNEGAAEMLIDTLGASIVNATD 287
Score = 44.4 bits (100), Expect = 6e-04
Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 7/122 (5%)
Query: 65 LKNNANIK-LDS-GWTPLMHACFHAQDKIVQYLLEK-DADPNLHSDSV-TPIMAACSNSS 120
L +NA + +DS G TPLM A + Q V+ L+ A+ L +S T + ACS
Sbjct: 310 LSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGH 369
Query: 121 ADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG 180
+ + I+ + DRN ++N + QTPL A +G V Q+LL ++ D++G
Sbjct: 370 ETSALL--ILEKITDRN-LINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENG 426
Query: 181 WT 182
+T
Sbjct: 427 YT 428
Score = 43.2 bits (97), Expect = 0.001
Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 11/173 (6%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
A+IN N E LI+ + N G TPL A F + +Q LL +A N + S
Sbjct: 262 AVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDS 321
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGR----VAV 162
TP+M A N +T+ +V + + L + D T L A S G + +
Sbjct: 322 TGKTPLMMAAEN--GQTNTVEMLVSS---ASAELTLQDNSKNTALHLACSKGHETSALLI 376
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT 215
+K+ D + I + T + A + +++ L+ KGA + VD++ T
Sbjct: 377 LEKITDRNL-INATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYT 428
>AK123496-1|BAC85629.1| 656|Homo sapiens protein ( Homo sapiens
cDNA FLJ41502 fis, clone BRTHA2007122, weakly similar
to ANKYRIN 2. ).
Length = 656
Score = 67.3 bits (157), Expect = 8e-11
Identities = 56/203 (27%), Positives = 94/203 (46%), Gaps = 10/203 (4%)
Query: 33 SQISSKK-KVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKI 91
+Q+S ++ V + L A G + V++ + + + N K GWTPLM+A + D I
Sbjct: 26 TQVSGEELDVPLDLHTAASIGQYEVVKECVQRR-ELDLNKKNGGGWTPLMYASYIGHDTI 84
Query: 92 VQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTP 150
V LLE N+ + + TP+M A SS N+ SI L+ + L + D G T
Sbjct: 85 VHLLLEAGVSVNVPTPEGQTPLMLA---SSCGNE---SIAYFLLQQGAELEMKDIQGWTA 138
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMRDQ-HGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
L S+G + + LLD N +R+ G+T + A I++ + G ++
Sbjct: 139 LFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAAGHEIIVQYFLNHGVKVDAR 198
Query: 210 DKSNRTLLEIANCHDHQVIIEIL 232
D S T +A + H I+ ++
Sbjct: 199 DHSGATARMLAKQYGHMKIVALM 221
Score = 56.4 bits (130), Expect = 1e-07
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 9/136 (6%)
Query: 110 TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDM 169
TP+M A S +DTI + L++ +N+ GQTPLM A S G ++A LL
Sbjct: 71 TPLMYA---SYIGHDTIVHL---LLEAGVSVNVPTPEGQTPLMLASSCGNESIAYFLLQQ 124
Query: 170 QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-SNRTLLEIANCHDHQVI 228
+EM+D GWTA+F ++ L++ GA + T L A H++I
Sbjct: 125 GAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAAGHEII 184
Query: 229 IE-ILKKSLNLD-DDH 242
++ L + +D DH
Sbjct: 185 VQYFLNHGVKVDARDH 200
Score = 37.5 bits (83), Expect = 0.072
Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 1/110 (0%)
Query: 127 YSIVCNLIDRNCI-LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVF 185
Y +V + R + LN + G TPLM A G + LL+ V++ + G T +
Sbjct: 48 YEVVKECVQRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEGQTPLM 107
Query: 186 WAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
A I L+++GA L D T L HQ ++ L S
Sbjct: 108 LASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDS 157
>AL139008-2|CAM15100.1| 1011|Homo sapiens ankyrin repeat domain 18B
protein.
Length = 1011
Score = 66.9 bits (156), Expect = 1e-10
Identities = 50/189 (26%), Positives = 93/189 (49%), Gaps = 8/189 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
+ A I G+ +VE + ++ +++ T L AC H + ++V LL++ N+
Sbjct: 38 IHRAAIKGDAAEVEHCLTRRFRD-LDVRDRKDRTVLHLACAHGRVQVVTLLLDRKCQINI 96
Query: 105 HSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ TP+M A + +I+ L+ R NI D YG T L A+ + ++A
Sbjct: 97 CDRLNRTPLMKAVHCQ----EEACAII--LLKRGANPNIKDIYGNTALHYAVYNEGTSLA 150
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
++LL NIE ++ G T + +A++ + ++E L++ A + VD RT L +A H
Sbjct: 151 ERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQH 210
Query: 224 DHQVIIEIL 232
+ I+ +L
Sbjct: 211 NLSSIVTLL 219
Score = 62.1 bits (144), Expect = 3e-09
Identities = 54/211 (25%), Positives = 98/211 (46%), Gaps = 10/211 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K L A +G ++ V L++ + + N +L+ TPLM A ++ LL++
Sbjct: 66 RKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNR--TPLMKAVHCQEEACAIILLKR 123
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
A+PN+ T + A N S+ L+ + + ++ G TPL+ AI+S
Sbjct: 124 GANPNIKDIYGNTALHYAVYNEGT------SLAERLLSHHANIEALNKEGNTPLLFAINS 177
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
R + + LL Q NI D TA+ AV HN I+ +L+++ ++ D +T
Sbjct: 178 RRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAE 237
Query: 218 EIANCHD-HQVIIEILKKSLNLDDDHKTDEN 247
+ A C D + +IL+ + +H ++N
Sbjct: 238 DYAFCCDLRSIQQQILEHKNKMLKNHLRNDN 268
>AB075857-1|BAB85563.1| 606|Homo sapiens KIAA1977 protein protein.
Length = 606
Score = 65.3 bits (152), Expect = 3e-10
Identities = 49/165 (29%), Positives = 76/165 (46%), Gaps = 8/165 (4%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYS 128
N K GWTPLM+A + D IV LLE N+ + + TP+M A SS N+ S
Sbjct: 13 NKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEGQTPLMLA---SSCGNE---S 66
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQ-HGWTAVFWA 187
I L+ + L + D G T L S+G + + LLD N +R+ G+T + A
Sbjct: 67 IAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEA 126
Query: 188 VHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
I++ + G ++ D S T +A + H I+ ++
Sbjct: 127 AAAGHEIIVQYFLNHGVKVDARDHSGATARMLAKQYGHMKIVALM 171
Score = 56.4 bits (130), Expect = 1e-07
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 9/136 (6%)
Query: 110 TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDM 169
TP+M A S +DTI + L++ +N+ GQTPLM A S G ++A LL
Sbjct: 21 TPLMYA---SYIGHDTIVHL---LLEAGVSVNVPTPEGQTPLMLASSCGNESIAYFLLQQ 74
Query: 170 QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-SNRTLLEIANCHDHQVI 228
+EM+D GWTA+F ++ L++ GA + T L A H++I
Sbjct: 75 GAELEMKDIQGWTALFHCTSAGHQHMVRFLLDSGANANVREPICGFTPLMEAAAAGHEII 134
Query: 229 IE-ILKKSLNLD-DDH 242
++ L + +D DH
Sbjct: 135 VQYFLNHGVKVDARDH 150
Score = 46.4 bits (105), Expect = 2e-04
Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIY 127
+ N+ G TPLM A + I +LL++ A+ + + C+++ +
Sbjct: 44 SVNVPTPEGQTPLMLASSCGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQH---- 99
Query: 128 SIVCNLIDRNCILNIGDRY-GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+V L+D N+ + G TPLM A ++G + Q L+ V ++ RD G TA
Sbjct: 100 -MVRFLLDSGANANVREPICGFTPLMEAAAAGHEIIVQYFLNHGVKVDARDHSGATARML 158
Query: 187 AVHHNQPEILEML 199
A + +I+ ++
Sbjct: 159 AKQYGHMKIVALM 171
Score = 37.5 bits (83), Expect = 0.072
Identities = 29/106 (27%), Positives = 42/106 (39%)
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
+ L R LN + G TPLM A G + LL+ V++ + G T + A
Sbjct: 2 ILRLFRRELDLNKKNGGGWTPLMYASYIGHDTIVHLLLEAGVSVNVPTPEGQTPLMLASS 61
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
I L+++GA L D T L HQ ++ L S
Sbjct: 62 CGNESIAYFLLQQGAELEMKDIQGWTALFHCTSAGHQHMVRFLLDS 107
>BC032799-1|AAH32799.1| 201|Homo sapiens ANKRD7 protein protein.
Length = 201
Score = 64.5 bits (150), Expect = 6e-10
Identities = 41/156 (26%), Positives = 84/156 (53%), Gaps = 7/156 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL AC + +V +L+E+ N+ S++ +P++ A + D TI L++
Sbjct: 8 TPLHLACANGHTDVVLFLIEQQCKINVRDSENKSPLIKAVQCQNEDCATI------LLNF 61
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
++ D T L A+ +++ +KLL+ + ++E +++ G+T + AV +N P+++
Sbjct: 62 GADPDLRDIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNPKMV 121
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ L+EKGA + D RT L +A + ++++L
Sbjct: 122 KFLLEKGADVNASDNYQRTALILAVSGEPPCLVKLL 157
Score = 36.3 bits (80), Expect = 0.17
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 40 KVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKD 99
+ L A+ ++ VE L+ E A K G+TPL+ A + K+V++LLEK
Sbjct: 71 RYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNK--DGYTPLLVAVINNNPKMVKFLLEKG 128
Query: 100 ADPN 103
AD N
Sbjct: 129 ADVN 132
Score = 35.1 bits (77), Expect = 0.39
Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 1/101 (0%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D+ +TPL A ++G V L++ Q I +RD + + AV + +L+ G
Sbjct: 3 DKKYRTPLHLACANGHTDVVLFLIEQQCKINVRDSENKSPLIKAVQCQNEDCATILLNFG 62
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIE-ILKKSLNLDDDHK 243
A D T+L A C ++E +L+ +L+ +K
Sbjct: 63 ADPDLRDIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNK 103
Score = 33.5 bits (73), Expect = 1.2
Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 74 DSGWTPLMHACFHAQD-KIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVC 131
D + ++H Q +V+ LLE +AD + D TP++ A N++ +V
Sbjct: 69 DIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNP------KMVK 122
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNI 173
L+++ +N D Y +T L+ A+S + + LL V +
Sbjct: 123 FLLEKGADVNASDNYQRTALILAVSGEPPCLVKLLLQQGVEL 164
>BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 27
(VPS9 domain) protein.
Length = 1050
Score = 64.1 bits (149), Expect = 7e-10
Identities = 48/184 (26%), Positives = 85/184 (46%), Gaps = 9/184 (4%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYS 128
N+ G +PL A H + ++ LL+ A+ ++D P+ AC +
Sbjct: 738 NVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGH------FQ 791
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+D N N D G TPL+ A S G + LL +I + G TA+ AV
Sbjct: 792 VVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAV 851
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILKKSL-NLDDDHKTDE 246
++E+L+ GA + ++K RT ++ A + +++++ + +LDD +TD
Sbjct: 852 IEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETDR 911
Query: 247 NSYL 250
Y+
Sbjct: 912 KEYV 915
Score = 46.4 bits (105), Expect = 2e-04
Identities = 43/160 (26%), Positives = 76/160 (47%), Gaps = 10/160 (6%)
Query: 59 DLINNELKNNANIKLDSG--WTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAA 115
DLI LK+ AN + PL AC ++V+ LL+ +A PN TP++ A
Sbjct: 758 DLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYA 817
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
CS + +V L+ +N + G T L A+ V V + LL ++++
Sbjct: 818 CSGGH------HELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQV 871
Query: 176 RDQHGWTAVFWAVHHNQ-PEILEMLIEKGARLTEVDKSNR 214
++ TAV A +++ E+L+++ A L +V +++R
Sbjct: 872 LNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETDR 911
Score = 37.9 bits (84), Expect = 0.055
Identities = 40/173 (23%), Positives = 69/173 (39%), Gaps = 14/173 (8%)
Query: 56 DVEDLINNELKNNANI----KLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVT 110
D E L++ L + + + + D G TPL A Q ++ L+ K A N T
Sbjct: 439 DCEKLVSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGAT 498
Query: 111 PIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQ 170
P+ AC S+ L+ + D G TPL A + G + L+
Sbjct: 499 PLHLACQKG------YQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYD 552
Query: 171 V---NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
V +++ ++ G T + A ++E L++ GA ++ T L+ A
Sbjct: 553 VESCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCA 605
Score = 37.9 bits (84), Expect = 0.055
Identities = 32/123 (26%), Positives = 57/123 (46%), Gaps = 4/123 (3%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLI 134
G TPL AC + LL A + ++ TP+ AC+ D + ++V +
Sbjct: 496 GATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGH--EDCVKALVYYDV 553
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+ +C L+IG+ G TPL A G V + LL + E++++ T + A++
Sbjct: 554 E-SCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKILS 612
Query: 195 ILE 197
++E
Sbjct: 613 VME 615
Score = 34.3 bits (75), Expect = 0.68
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 7/141 (4%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G TPL A G+ ++ L+ + D HG T + A + +L+
Sbjct: 460 DDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYK 519
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEIL----KKSLNLDDDHKTDENSYLNHQLTSWQD 259
A D + T L +A + H+ ++ L +S LD ++ + H W
Sbjct: 520 ASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPL--HIAARW-G 576
Query: 260 YYPGIEKNERPNYKNEIQNLL 280
Y IE + EIQN L
Sbjct: 577 YQGVIETLLQNGASTEIQNRL 597
>AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein
protein.
Length = 407
Score = 64.1 bits (149), Expect = 7e-10
Identities = 48/184 (26%), Positives = 85/184 (46%), Gaps = 9/184 (4%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYS 128
N+ G +PL A H + ++ LL+ A+ ++D P+ AC +
Sbjct: 95 NVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGH------FQ 148
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+D N N D G TPL+ A S G + LL +I + G TA+ AV
Sbjct: 149 VVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAV 208
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILKKSL-NLDDDHKTDE 246
++E+L+ GA + ++K RT ++ A + +++++ + +LDD +TD
Sbjct: 209 IEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETDR 268
Query: 247 NSYL 250
Y+
Sbjct: 269 KEYV 272
Score = 46.4 bits (105), Expect = 2e-04
Identities = 43/160 (26%), Positives = 76/160 (47%), Gaps = 10/160 (6%)
Query: 59 DLINNELKNNANIKLDSG--WTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAA 115
DLI LK+ AN + PL AC ++V+ LL+ +A PN TP++ A
Sbjct: 115 DLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYA 174
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
CS + +V L+ +N + G T L A+ V V + LL ++++
Sbjct: 175 CSGGH------HELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQV 228
Query: 176 RDQHGWTAVFWAVHHNQ-PEILEMLIEKGARLTEVDKSNR 214
++ TAV A +++ E+L+++ A L +V +++R
Sbjct: 229 LNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETDR 268
>AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein.
Length = 1060
Score = 64.1 bits (149), Expect = 7e-10
Identities = 48/184 (26%), Positives = 85/184 (46%), Gaps = 9/184 (4%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYS 128
N+ G +PL A H + ++ LL+ A+ ++D P+ AC +
Sbjct: 748 NVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGH------FQ 801
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+D N N D G TPL+ A S G + LL +I + G TA+ AV
Sbjct: 802 VVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAV 861
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILKKSL-NLDDDHKTDE 246
++E+L+ GA + ++K RT ++ A + +++++ + +LDD +TD
Sbjct: 862 IEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETDR 921
Query: 247 NSYL 250
Y+
Sbjct: 922 KEYV 925
Score = 46.4 bits (105), Expect = 2e-04
Identities = 43/160 (26%), Positives = 76/160 (47%), Gaps = 10/160 (6%)
Query: 59 DLINNELKNNANIKLDSG--WTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAA 115
DLI LK+ AN + PL AC ++V+ LL+ +A PN TP++ A
Sbjct: 768 DLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYA 827
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
CS + +V L+ +N + G T L A+ V V + LL ++++
Sbjct: 828 CSGGH------HELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQV 881
Query: 176 RDQHGWTAVFWAVHHNQ-PEILEMLIEKGARLTEVDKSNR 214
++ TAV A +++ E+L+++ A L +V +++R
Sbjct: 882 LNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETDR 921
Score = 37.9 bits (84), Expect = 0.055
Identities = 40/173 (23%), Positives = 69/173 (39%), Gaps = 14/173 (8%)
Query: 56 DVEDLINNELKNNANI----KLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVT 110
D E L++ L + + + + D G TPL A Q ++ L+ K A N T
Sbjct: 449 DCEKLVSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGAT 508
Query: 111 PIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQ 170
P+ AC S+ L+ + D G TPL A + G + L+
Sbjct: 509 PLHLACQKG------YQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYD 562
Query: 171 V---NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
V +++ ++ G T + A ++E L++ GA ++ T L+ A
Sbjct: 563 VESCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCA 615
Score = 37.9 bits (84), Expect = 0.055
Identities = 32/123 (26%), Positives = 57/123 (46%), Gaps = 4/123 (3%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLI 134
G TPL AC + LL A + ++ TP+ AC+ D + ++V +
Sbjct: 506 GATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGH--EDCVKALVYYDV 563
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+ +C L+IG+ G TPL A G V + LL + E++++ T + A++
Sbjct: 564 E-SCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKILS 622
Query: 195 ILE 197
++E
Sbjct: 623 VME 625
Score = 34.3 bits (75), Expect = 0.68
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 7/141 (4%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G TPL A G+ ++ L+ + D HG T + A + +L+
Sbjct: 470 DDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYK 529
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEIL----KKSLNLDDDHKTDENSYLNHQLTSWQD 259
A D + T L +A + H+ ++ L +S LD ++ + H W
Sbjct: 530 ASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPL--HIAARW-G 586
Query: 260 YYPGIEKNERPNYKNEIQNLL 280
Y IE + EIQN L
Sbjct: 587 YQGVIETLLQNGASTEIQNRL 607
>AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat
containing protein protein.
Length = 1101
Score = 64.1 bits (149), Expect = 7e-10
Identities = 32/106 (30%), Positives = 54/106 (50%)
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+ IV L+ +N+ D+ G+TPLM A S G + LL +I + D+ G TA+ W
Sbjct: 181 WQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSW 240
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
A ++ L++ GA DK+ RT L++A + +++ L
Sbjct: 241 ACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFL 286
Score = 42.3 bits (95), Expect = 0.003
Identities = 47/175 (26%), Positives = 75/175 (42%), Gaps = 11/175 (6%)
Query: 43 VALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP 102
V L + G+ + V+ L+ + + N+ G TPLM A V +LL + A
Sbjct: 170 VPLFSTVRQGHWQIVDLLLTHGA--DVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASI 227
Query: 103 NL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
L + +T + AC S+V +L+D + D+ G+TPL A G
Sbjct: 228 ALMDKEGLTALSWACLKGHL------SVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAE 281
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA--RLTEVDKSNR 214
V Q L+D IE D G + AV ++ L++K + RL++V R
Sbjct: 282 VVQFLVDHGAMIEHVDYSGMRPLDRAVGCPNTSVVVTLLKKRSQDRLSDVXSRPR 336
Score = 41.1 bits (92), Expect = 0.006
Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 1/104 (0%)
Query: 130 VCNLI-DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
VC L+ ++ + +R G PL + G + LL ++ M D+ G T + A
Sbjct: 150 VCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAA 209
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++ L+ +GA + +DK T L A H ++ L
Sbjct: 210 SEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSL 253
Score = 30.7 bits (66), Expect = 8.3
Identities = 16/67 (23%), Positives = 33/67 (49%)
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LL+ N++ + G T + +A I+ +L +K A++ +DK+ + L A H
Sbjct: 5 LLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGH 64
Query: 226 QVIIEIL 232
+++ L
Sbjct: 65 LEVVKFL 71
>AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein.
Length = 394
Score = 64.1 bits (149), Expect = 7e-10
Identities = 52/208 (25%), Positives = 97/208 (46%), Gaps = 8/208 (3%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A NG+ + +E L+ + + + +I+ + G T L A F + V+ L+ + A +
Sbjct: 21 LHLAAYNGHHQALEVLLQSLV--DLDIRDEKGRTALDLAAFKGHTECVEALINQGASIFV 78
Query: 105 HSDSV--TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ TP+ A+ N + ++ + D +++ D GQTPLM A++ G +
Sbjct: 79 KDNVTKRTPLHASVING---HTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDA 135
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
LL+ + N++ D G TA+ + E ++ML+E+ + D RT L A
Sbjct: 136 VSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAA 195
Query: 223 HDHQV-IIEILKKSLNLDDDHKTDENSY 249
H + E+L+ +L+ +D D Y
Sbjct: 196 RGHATWLSELLQMALSEEDCCFKDNQGY 223
Score = 63.3 bits (147), Expect = 1e-09
Identities = 50/184 (27%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 45 LQEAIINGNMKDVEDLINNEL-KNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L A G+ + +L+ L + + K + G+TPL AC++ + ++ LLE+
Sbjct: 190 LHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKCFRK 249
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ TP+ A N D+ S++ ID + I++ D G+TPL A + V
Sbjct: 250 FIGNPFTPLHCAIIN---DHGNCASLLLGAID-SSIVSCRDDKGRTPLHAAAFADHVECL 305
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG-ARLTEVDKSNRTLLEIANC 222
Q LL + D G TA+ A + Q +++L+ A LT DK T L +A
Sbjct: 306 QLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACS 365
Query: 223 HDHQ 226
H+
Sbjct: 366 KGHE 369
Score = 39.9 bits (89), Expect = 0.014
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
++PL A +G + LL V++++RD+ G TA+ A E +E LI +GA +
Sbjct: 18 KSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINQGASIF 77
Query: 208 EVDK-SNRTLLEIANCHDHQVIIEIL 232
D + RT L + + H + + +L
Sbjct: 78 VKDNVTKRTPLHASVINGHTLCLRLL 103
>AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein.
Length = 1864
Score = 64.1 bits (149), Expect = 7e-10
Identities = 32/106 (30%), Positives = 54/106 (50%)
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+ IV L+ +N+ D+ G+TPLM A S G + LL +I + D+ G TA+ W
Sbjct: 954 WQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSW 1013
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
A ++ L++ GA DK+ RT L++A + +++ L
Sbjct: 1014 ACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFL 1059
Score = 47.6 bits (108), Expect = 7e-05
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 9/165 (5%)
Query: 43 VALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP 102
V L + G+ + V+ L+ + + N+ G TPLM A V +LL + A
Sbjct: 943 VPLFSTVRQGHWQIVDLLLTHGA--DVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASI 1000
Query: 103 NL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
L + +T + AC S+V +L+D + D+ G+TPL A G
Sbjct: 1001 ALMDKEGLTALSWACLKGHL------SVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAE 1054
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL 206
V Q L+D IE D G + AV ++ L++KGA++
Sbjct: 1055 VVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKI 1099
Score = 41.1 bits (92), Expect = 0.006
Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 1/104 (0%)
Query: 130 VCNLI-DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
VC L+ ++ + +R G PL + G + LL ++ M D+ G T + A
Sbjct: 923 VCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAA 982
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++ L+ +GA + +DK T L A H ++ L
Sbjct: 983 SEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSL 1026
Score = 31.1 bits (67), Expect = 6.3
Identities = 17/75 (22%), Positives = 35/75 (46%)
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
G + LL+ N++ + G T + +A I+ +L +K A++ +DK+ + L
Sbjct: 770 GYTEMVALLLEFGANVDASSESGLTPLGYAAAAGYLSIVVLLCKKRAKVDHLDKNGQCAL 829
Query: 218 EIANCHDHQVIIEIL 232
A H +++ L
Sbjct: 830 VHAALRGHLEVVKFL 844
>X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein.
Length = 1001
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 448 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 507
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 508 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 561
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 562 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 621
Query: 226 QVIIEIL 232
I E+L
Sbjct: 622 AAIAEVL 628
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 511 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 566
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 567 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 626
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 627 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 679
>BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 922
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 369 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 428
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 429 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 482
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 483 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 542
Query: 226 QVIIEIL 232
I E+L
Sbjct: 543 AAIAEVL 549
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 432 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 487
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 488 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 547
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 548 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 600
>BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 888
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 335 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 394
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 395 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 448
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 449 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 508
Query: 226 QVIIEIL 232
I E+L
Sbjct: 509 AAIAEVL 515
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 398 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 453
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 454 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 513
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 514 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 566
>BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein.
Length = 1198
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 645 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 704
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 705 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 758
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 759 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 818
Query: 226 QVIIEIL 232
I E+L
Sbjct: 819 AAIAEVL 825
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 708 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 763
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 764 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 823
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 824 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 876
>BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein.
Length = 1001
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 448 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 507
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 508 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 561
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 562 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 621
Query: 226 QVIIEIL 232
I E+L
Sbjct: 622 AAIAEVL 628
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 511 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 566
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 567 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 626
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 627 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 679
>BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein.
Length = 1209
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 656 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 715
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 716 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 769
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 770 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 829
Query: 226 QVIIEIL 232
I E+L
Sbjct: 830 AAIAEVL 836
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 719 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 774
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 775 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 834
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 835 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 887
>BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein.
Length = 1043
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 490 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 549
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 550 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 603
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 604 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 663
Query: 226 QVIIEIL 232
I E+L
Sbjct: 664 AAIAEVL 670
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 553 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 608
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 609 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 668
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 669 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 721
>BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 448 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 507
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 508 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 561
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 562 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 621
Query: 226 QVIIEIL 232
I E+L
Sbjct: 622 AAIAEVL 628
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 511 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 566
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 567 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 626
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 627 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 679
>AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1210
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 657 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 716
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 717 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 770
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 771 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 830
Query: 226 QVIIEIL 232
I E+L
Sbjct: 831 AAIAEVL 837
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 720 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 775
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 776 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 835
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 836 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 888
>AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1176
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 623 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 682
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 683 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 736
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 737 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 796
Query: 226 QVIIEIL 232
I E+L
Sbjct: 797 AAIAEVL 803
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 686 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 741
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 742 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 801
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 802 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 854
>AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 657 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 716
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 717 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 770
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 771 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 830
Query: 226 QVIIEIL 232
I E+L
Sbjct: 831 AAIAEVL 837
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 720 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 775
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 776 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 835
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 836 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 888
>AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 623 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 682
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 683 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 736
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 737 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 796
Query: 226 QVIIEIL 232
I E+L
Sbjct: 797 AAIAEVL 803
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 686 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 741
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 742 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 801
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 802 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 854
>AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 714 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 773
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 774 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 827
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 828 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 887
Query: 226 QVIIEIL 232
I E+L
Sbjct: 888 AAIAEVL 894
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 777 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 832
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 833 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 892
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 893 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 945
>AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 680 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 739
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 740 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 793
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 794 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 853
Query: 226 QVIIEIL 232
I E+L
Sbjct: 854 AAIAEVL 860
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 743 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 798
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 799 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 858
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 859 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 911
>AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 623 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 682
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 683 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 736
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 737 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 796
Query: 226 QVIIEIL 232
I E+L
Sbjct: 797 AAIAEVL 803
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 686 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 741
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 742 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 801
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 802 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 854
>AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 657 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 716
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 717 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 770
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 771 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 830
Query: 226 QVIIEIL 232
I E+L
Sbjct: 831 AAIAEVL 837
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 720 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 775
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 776 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 835
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 836 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 888
>AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 714 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 773
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 774 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 827
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 828 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 887
Query: 226 QVIIEIL 232
I E+L
Sbjct: 888 AAIAEVL 894
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 777 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 832
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 833 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 892
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 893 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 945
>AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 680 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 739
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 740 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 793
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 794 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 853
Query: 226 QVIIEIL 232
I E+L
Sbjct: 854 AAIAEVL 860
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 743 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 798
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 799 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 858
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 859 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 911
>AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens
cDNA FLJ39767 fis, clone SPLEN2000607, weakly similar to
ANKYRIN 1. ).
Length = 919
Score = 63.7 bits (148), Expect = 1e-09
Identities = 50/184 (27%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 45 LQEAIINGNMKDVEDLINNEL-KNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L A G+ + +L+ L + + K + G+TPL AC++ + ++ LLE+
Sbjct: 715 LHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKCFRK 774
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ TP+ A N D+ S++ ID + I++ D G+TPL A + V
Sbjct: 775 FIGNPFTPLHCAIIN---DHGNCASLLLGAID-SSIVSCRDDKGRTPLRAAAFADHVECL 830
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG-ARLTEVDKSNRTLLEIANC 222
Q LL + D G TA+ A + Q +++L+ A LT DK T L +A
Sbjct: 831 QLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACS 890
Query: 223 HDHQ 226
H+
Sbjct: 891 KGHE 894
Score = 63.3 bits (147), Expect = 1e-09
Identities = 52/208 (25%), Positives = 96/208 (46%), Gaps = 8/208 (3%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A NG+ + +E L+ + + + +I+ + G T L A F + V+ L+ A +
Sbjct: 546 LHLAAYNGHHQALEVLLQSLV--DLDIRDEKGRTALDLAAFKGHTECVEALINPGASIFV 603
Query: 105 HSDSV--TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ TP+ A+ N + ++ + D +++ D GQTPLM A++ G +
Sbjct: 604 KDNVTKRTPLHASVING---HTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDA 660
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
LL+ + N++ D G TA+ + E ++ML+E+ + D RT L A
Sbjct: 661 VSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAA 720
Query: 223 HDHQV-IIEILKKSLNLDDDHKTDENSY 249
H + E+L+ +L+ +D D Y
Sbjct: 721 RGHATWLSELLQMALSEEDCCFKDNQGY 748
Score = 61.3 bits (142), Expect = 5e-09
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E +I L ++ N+ G T L HA +
Sbjct: 71 HSADVNARDKNWQTPLHVAAANKAVKCAEVII--PLLSSVNVSDRGGRTALHHAALNGHV 128
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V LL K A+ N + + +V LI+ + D+ G T
Sbjct: 129 EMVNLLLAKGANINAFDKKDRRALHWAAYMGH-----LDVVALLINHGAEVTCKDKKGYT 183
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A S+G++ V + LL++ V I+ + +G TA+ A ++ Q ++ LI+ GA + +
Sbjct: 184 PLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQP 243
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
+ + T L A H + +E+L
Sbjct: 244 NNNGFTPLHFAAASTHGALCLELL 267
Score = 57.2 bits (132), Expect = 8e-08
Identities = 57/201 (28%), Positives = 91/201 (45%), Gaps = 14/201 (6%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
KK AL A G++ V LIN+ + K G+TPL A + Q +V++LL
Sbjct: 146 KKDRRALHWAAYMGHLDVVALLINHGAEVTCKDK--KGYTPLHAAASNGQINVVKHLLNL 203
Query: 99 DAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
+ ++ T + AC N ++V LID +N + G TPL A +S
Sbjct: 204 GVEIDEINVYGNTALHIACYNGQD------AVVNELIDYGANVNQPNNNGFTPLHFAAAS 257
Query: 158 GRVAVAQKLL---DMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
A+ +LL VNI+ +D G + + H + + LI+ G + VDK
Sbjct: 258 THGALCLELLVNNGADVNIQSKD--GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGN 315
Query: 215 TLLEIANCHDHQVIIEILKKS 235
T L +A + H+++I L+ S
Sbjct: 316 TPLHVAARYGHELLINTLRTS 336
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/156 (26%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL A F +I++ L+ A N + +TP+ A ++ S + + LI
Sbjct: 18 TPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQV------LIKH 71
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
+ +N D+ QTPL A ++ V A+ ++ + ++ + D+ G TA+ A + E++
Sbjct: 72 SADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMV 131
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+L+ KGA + DK +R L A H ++ +L
Sbjct: 132 NLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALL 167
Score = 47.6 bits (108), Expect = 7e-05
Identities = 50/220 (22%), Positives = 99/220 (45%), Gaps = 16/220 (7%)
Query: 30 DYSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHA 87
++ ++++ K KK L A NG + V+ L+N ++ + N+ G T L AC++
Sbjct: 169 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVY---GNTALHIACYNG 225
Query: 88 QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCN--LIDRNCILNIGD 144
QD +V L++ A+ N +++ TP+ A +++ + +C L++ +NI
Sbjct: 226 QDAVVNELIDYGANVNQPNNNGFTPLHFAAAST-------HGALCLELLVNNGADVNIQS 278
Query: 145 RYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA 204
+ G++PL GR +Q L+ I+ D+ G T + A + ++ L GA
Sbjct: 279 KDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGA 338
Query: 205 RLTEVDKSNRTLLEIANCHDH-QVIIEILKKSLNLDDDHK 243
+ + L +A + H ++L +D K
Sbjct: 339 DTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDK 378
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 9/151 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADP-NLHSDSVTPIMAACSNSSADNDTIYSIVCN-L 133
G TPL A + + ++ L AD S+ P+ A N+ +D C L
Sbjct: 314 GNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSD-------CCRKL 366
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ ++ D++G+T L A + G V + L + +D+ G T + +A +
Sbjct: 367 LSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHF 426
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHD 224
+E L+ GA + E D RT L A D
Sbjct: 427 HCIETLVTTGANVNETDDWGRTALHYAAASD 457
Score = 40.3 bits (90), Expect = 0.010
Identities = 37/163 (22%), Positives = 74/163 (45%), Gaps = 10/163 (6%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADND----TIYSIVCNLIDRNC 138
A FH +DK + L A N H + ++ +N + +D ++ + +DRN
Sbjct: 404 ADFHKKDKCGRTPLHYAA-ANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNK 462
Query: 139 IL--NIGDRYGQTPLMRAISSGRVAVAQK-LLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
+ N D + R + + + LL N +RD+ G+ ++ +A + +
Sbjct: 463 TILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQC 522
Query: 196 LEMLIEK-GARLTEVDK-SNRTLLEIANCHDHQVIIEILKKSL 236
LE+L+E+ + E D + ++ L +A + H +E+L +SL
Sbjct: 523 LELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSL 565
Score = 39.1 bits (87), Expect = 0.024
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
++PL A +G + LL V++++RD+ G TA+ A E +E LI GA +
Sbjct: 543 KSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINPGASIF 602
Query: 208 EVDK-SNRTLLEIANCHDHQVIIEIL 232
D + RT L + + H + + +L
Sbjct: 603 VKDNVTKRTPLHASVINGHTLCLRLL 628
>AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein.
Length = 1210
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 657 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 716
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 717 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 770
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 771 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 830
Query: 226 QVIIEIL 232
I E+L
Sbjct: 831 AAIAEVL 837
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 720 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 775
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 776 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 835
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 836 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 888
>AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 63.7 bits (148), Expect = 1e-09
Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 448 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 507
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 508 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 561
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
L QV++ +D GWT + WA H E++ ML+ +GA +T D L A+
Sbjct: 562 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGS 621
Query: 226 QVIIEIL 232
I E+L
Sbjct: 622 AAIAEVL 628
Score = 36.3 bits (80), Expect = 0.17
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 5/173 (2%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
TPLM A + ++ +Y++++ + + C + +A + + L
Sbjct: 511 TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGS----TCLHHAAKIGNLEMVSLLLSTGQ 566
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
+N D G TP++ A + V + LL ++ + D + WA I E
Sbjct: 567 VDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAE 626
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHD-HQVIIEILKKSLNLDDDHKTDENSY 249
+L+ L V+ T L IA H ++ L + N + +K + ++
Sbjct: 627 VLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAW 679
>BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/131 (27%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ N N+ +R G TPL A+ V + LL ++++ +D+ WTA+ +A +
Sbjct: 457 LLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGD 516
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLDDDHKTDENSYLN 251
+L+EK A + EVD RT + +A H + I+ I L++ +++ K +++L
Sbjct: 517 ESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGK---DAWLP 573
Query: 252 HQLTSWQDYYP 262
+WQ + P
Sbjct: 574 LHYAAWQGHLP 584
Score = 55.6 bits (128), Expect = 3e-07
Identities = 55/232 (23%), Positives = 100/232 (43%), Gaps = 12/232 (5%)
Query: 5 RPAGFSDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNE 64
R +G S DS G +S + + + L +AI++G+ + ++ +
Sbjct: 370 RLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQ 429
Query: 65 LKNNANIKLDSGWTPLMHACFHA-QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSAD 122
+ ++ LDSG L+H A Q++ ++LL +A+PNL + TP+ A
Sbjct: 430 ---DVDLALDSG-ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVER---- 481
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ +V L+ R +N D T L A +G + + LL+ ++ D G T
Sbjct: 482 --RVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 539
Query: 183 AVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
+ A H Q I+ +L+ +G ++ K L A H I+++L K
Sbjct: 540 PMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAK 591
Score = 55.6 bits (128), Expect = 3e-07
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS---DSVTPI 112
E+++ L+ ++ L W PL +A + IV+ LL K ++++ D TP+
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPL 608
Query: 113 MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVN 172
A Y + LID +N+ QTPL A +G + A+ LL
Sbjct: 609 HLAAQRGH------YRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAG 662
Query: 173 IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E G+TA+ A + +++L+E+ A + N+T L +A H H ++E L
Sbjct: 663 KEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEEL 722
Score = 47.6 bits (108), Expect = 7e-05
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Query: 65 LKNNANI-KLD-SGWTPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSA 121
L+ NA++ ++D G TP+ AC H Q+ IV+ LL + D +L D+ P+ A
Sbjct: 524 LEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHL 583
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
I ++ +N G+TPL A G VA+ L+D+ ++ +
Sbjct: 584 ---PIVKLLAK--QPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ 638
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
T + A +L+ +GA V T L +A + H +++L
Sbjct: 639 TPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLL 689
>BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/131 (27%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ N N+ +R G TPL A+ V + LL ++++ +D+ WTA+ +A +
Sbjct: 457 LLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGD 516
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLDDDHKTDENSYLN 251
+L+EK A + EVD RT + +A H + I+ I L++ +++ K +++L
Sbjct: 517 ESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGK---DAWLP 573
Query: 252 HQLTSWQDYYP 262
+WQ + P
Sbjct: 574 LHYAAWQGHLP 584
Score = 55.6 bits (128), Expect = 3e-07
Identities = 55/232 (23%), Positives = 100/232 (43%), Gaps = 12/232 (5%)
Query: 5 RPAGFSDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNE 64
R +G S DS G +S + + + L +AI++G+ + ++ +
Sbjct: 370 RLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQ 429
Query: 65 LKNNANIKLDSGWTPLMHACFHA-QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSAD 122
+ ++ LDSG L+H A Q++ ++LL +A+PNL + TP+ A
Sbjct: 430 ---DVDLALDSG-ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVER---- 481
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ +V L+ R +N D T L A +G + + LL+ ++ D G T
Sbjct: 482 --RVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 539
Query: 183 AVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
+ A H Q I+ +L+ +G ++ K L A H I+++L K
Sbjct: 540 PMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAK 591
Score = 55.6 bits (128), Expect = 3e-07
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS---DSVTPI 112
E+++ L+ ++ L W PL +A + IV+ LL K ++++ D TP+
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPL 608
Query: 113 MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVN 172
A Y + LID +N+ QTPL A +G + A+ LL
Sbjct: 609 HLAAQRGH------YRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAG 662
Query: 173 IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E G+TA+ A + +++L+E+ A + N+T L +A H H ++E L
Sbjct: 663 KEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEEL 722
Score = 47.6 bits (108), Expect = 7e-05
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Query: 65 LKNNANI-KLD-SGWTPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSA 121
L+ NA++ ++D G TP+ AC H Q+ IV+ LL + D +L D+ P+ A
Sbjct: 524 LEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHL 583
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
I ++ +N G+TPL A G VA+ L+D+ ++ +
Sbjct: 584 ---PIVKLLAK--QPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ 638
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
T + A +L+ +GA V T L +A + H +++L
Sbjct: 639 TPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLL 689
>BC056266-1|AAH56266.1| 357|Homo sapiens ANKRD18A protein protein.
Length = 357
Score = 63.3 bits (147), Expect = 1e-09
Identities = 55/211 (26%), Positives = 97/211 (45%), Gaps = 10/211 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K L A +G ++ V L++ + + +L+ TPLM A ++ LLE
Sbjct: 66 RKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNR--TPLMKAVHSQEEACAIVLLEC 123
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
A+PN+ T + A N S+ L+ + + ++ G TPL+ AI+S
Sbjct: 124 GANPNIEDIYGNTALHYAVYNKGT------SLAERLLSHHANIEALNKEGNTPLLFAINS 177
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
R + + LL Q NI D TA+ AV HN I+ +L+++ R++ D +T
Sbjct: 178 RRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAE 237
Query: 218 EIANCHD-HQVIIEILKKSLNLDDDHKTDEN 247
+ A C D + +IL+ + +H ++N
Sbjct: 238 DYALCSDLRSIRQQILEHKNKMLKNHLRNDN 268
Score = 62.9 bits (146), Expect = 2e-09
Identities = 51/190 (26%), Positives = 94/190 (49%), Gaps = 10/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKN-NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ A I G+ +VE + ++ +A + D T L AC H + ++V LL + +
Sbjct: 38 IHRAAIKGDAAEVERCLTRRFRDLDARDRKDR--TVLHLACAHGRVQVVTLLLHRRCQID 95
Query: 104 LHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ + TP+M A + + +IV L++ NI D YG T L A+ + ++
Sbjct: 96 ICDRLNRTPLMKAVHSQ----EEACAIV--LLECGANPNIEDIYGNTALHYAVYNKGTSL 149
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A++LL NIE ++ G T + +A++ + ++E L++ A + VD RT L +A
Sbjct: 150 AERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQ 209
Query: 223 HDHQVIIEIL 232
H+ I+ +L
Sbjct: 210 HNLSSIVTLL 219
>AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein.
Length = 832
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/131 (27%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ N N+ +R G TPL A+ V + LL ++++ +D+ WTA+ +A +
Sbjct: 505 LLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGD 564
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLDDDHKTDENSYLN 251
+L+EK A + EVD RT + +A H + I+ I L++ +++ K +++L
Sbjct: 565 ESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGK---DAWLP 621
Query: 252 HQLTSWQDYYP 262
+WQ + P
Sbjct: 622 LHYAAWQGHLP 632
Score = 56.4 bits (130), Expect = 1e-07
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS---DSVTPI 112
E+++ L+ ++ L W PL +A + IV+ LL K ++++ D TP+
Sbjct: 598 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPL 656
Query: 113 MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVN 172
A Y + LID +N+ QTPL A +G + A+ LL
Sbjct: 657 HLAAQRGH------YRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAG 710
Query: 173 IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E G+TA+ A + +++L+E+ A + N+T L +A H H ++E L
Sbjct: 711 KEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEEL 770
Score = 55.6 bits (128), Expect = 3e-07
Identities = 55/232 (23%), Positives = 100/232 (43%), Gaps = 12/232 (5%)
Query: 5 RPAGFSDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNE 64
R +G S DS G +S + + + L +AI++G+ + ++ +
Sbjct: 418 RLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQ 477
Query: 65 LKNNANIKLDSGWTPLMHACFHA-QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSAD 122
+ ++ LDSG L+H A Q++ ++LL +A+PNL + TP+ A
Sbjct: 478 ---DVDLALDSG-ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVER---- 529
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ +V L+ R +N D T L A +G + + LL+ ++ D G T
Sbjct: 530 --RVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 587
Query: 183 AVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
+ A H Q I+ +L+ +G ++ K L A H I+++L K
Sbjct: 588 PMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAK 639
Score = 46.4 bits (105), Expect = 2e-04
Identities = 42/171 (24%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Query: 65 LKNNANI-KLD-SGWTPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSA 121
L+ NA++ ++D G TP+ AC H Q+ IV+ LL + D +L D+ P+ A
Sbjct: 572 LEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHL 631
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
I ++ +N G+TPL A G VA+ L+D+ ++ +
Sbjct: 632 ---PIVKLLAK--QPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ 686
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
T + A +L+ +GA + T L +A + H +++L
Sbjct: 687 TPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLL 737
>AL591543-1|CAI17285.1| 992|Homo sapiens ankyrin repeat domain 18A
protein.
Length = 992
Score = 63.3 bits (147), Expect = 1e-09
Identities = 55/211 (26%), Positives = 97/211 (45%), Gaps = 10/211 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K L A +G ++ V L++ + + +L+ TPLM A ++ LLE
Sbjct: 66 RKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNR--TPLMKAVHSQEEACAIVLLEC 123
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
A+PN+ T + A N S+ L+ + + ++ G TPL+ AI+S
Sbjct: 124 GANPNIEDIYGNTALHYAVYNKGT------SLAERLLSHHANIEALNKEGNTPLLFAINS 177
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
R + + LL Q NI D TA+ AV HN I+ +L+++ R++ D +T
Sbjct: 178 RRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAE 237
Query: 218 EIANCHD-HQVIIEILKKSLNLDDDHKTDEN 247
+ A C D + +IL+ + +H ++N
Sbjct: 238 DYALCSDLRSIRQQILEHKNKMLKNHLRNDN 268
Score = 62.9 bits (146), Expect = 2e-09
Identities = 51/190 (26%), Positives = 94/190 (49%), Gaps = 10/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKN-NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ A I G+ +VE + ++ +A + D T L AC H + ++V LL + +
Sbjct: 38 IHRAAIKGDAAEVERCLTRRFRDLDARDRKDR--TVLHLACAHGRVQVVTLLLHRRCQID 95
Query: 104 LHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ + TP+M A + + +IV L++ NI D YG T L A+ + ++
Sbjct: 96 ICDRLNRTPLMKAVHSQ----EEACAIV--LLECGANPNIEDIYGNTALHYAVYNKGTSL 149
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A++LL NIE ++ G T + +A++ + ++E L++ A + VD RT L +A
Sbjct: 150 AERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQ 209
Query: 223 HDHQVIIEIL 232
H+ I+ +L
Sbjct: 210 HNLSSIVTLL 219
>AL357148-2|CAI16567.1| 1341|Homo sapiens breast cancer antigen
NY-BR-1 protein.
Length = 1341
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 8/173 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTI 126
N NI+ T L AC + +++V +L+++ + L + TP+M A +
Sbjct: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQ---CHQEAC 65
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+I LID +N+ D YG T L A+ S ++V KLL IE+ ++ T +
Sbjct: 66 ANI---LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLL 122
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
++ +I+E L+ K A V+K T L +A CH I+ +L + N+D
Sbjct: 123 SITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQ-NVD 174
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 86/195 (44%), Gaps = 11/195 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A +NG+ + V L++ K ++ TPLM A Q+ L++ AD N
Sbjct: 20 ALHWACVNGHEEVVTFLVDR--KCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADIN 77
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
L + + A I S+V L+ ++ + ++ TPL+ +I+ +
Sbjct: 78 L-----VDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIV 132
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA-NC 222
+ LL N +++ TA+ AV H EI+ ML+++ + D T A C
Sbjct: 133 EFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTC 192
Query: 223 ---HDHQVIIEILKK 234
H H+ I+E ++K
Sbjct: 193 GFHHIHEQIMEYIRK 207
Score = 35.9 bits (79), Expect = 0.22
Identities = 15/54 (27%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 171 VNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-LLEIANCH 223
+N+ ++D TA+ WA + E++ L+++ +L +D +RT L++ CH
Sbjct: 8 INLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCH 61
>AL357148-1|CAI16568.1| 1460|Homo sapiens ankyrin repeat domain 30A
protein.
Length = 1460
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 8/173 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTI 126
N NI+ T L AC + +++V +L+++ + L + TP+M A +
Sbjct: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQ---CHQEAC 65
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+I LID +N+ D YG T L A+ S ++V KLL IE+ ++ T +
Sbjct: 66 ANI---LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLL 122
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
++ +I+E L+ K A V+K T L +A CH I+ +L + N+D
Sbjct: 123 SITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQ-NVD 174
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 86/195 (44%), Gaps = 11/195 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A +NG+ + V L++ K ++ TPLM A Q+ L++ AD N
Sbjct: 20 ALHWACVNGHEEVVTFLVDR--KCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADIN 77
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
L + + A I S+V L+ ++ + ++ TPL+ +I+ +
Sbjct: 78 L-----VDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIV 132
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA-NC 222
+ LL N +++ TA+ AV H EI+ ML+++ + D T A C
Sbjct: 133 EFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTC 192
Query: 223 ---HDHQVIIEILKK 234
H H+ I+E ++K
Sbjct: 193 GFHHIHEQIMEYIRK 207
Score = 35.9 bits (79), Expect = 0.22
Identities = 15/54 (27%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 171 VNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-LLEIANCH 223
+N+ ++D TA+ WA + E++ L+++ +L +D +RT L++ CH
Sbjct: 8 INLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCH 61
>AL157387-4|CAH71319.1| 1460|Homo sapiens ankyrin repeat domain 30A
protein.
Length = 1460
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 8/173 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTI 126
N NI+ T L AC + +++V +L+++ + L + TP+M A +
Sbjct: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQ---CHQEAC 65
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+I LID +N+ D YG T L A+ S ++V KLL IE+ ++ T +
Sbjct: 66 ANI---LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLL 122
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
++ +I+E L+ K A V+K T L +A CH I+ +L + N+D
Sbjct: 123 SITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQ-NVD 174
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 86/195 (44%), Gaps = 11/195 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A +NG+ + V L++ K ++ TPLM A Q+ L++ AD N
Sbjct: 20 ALHWACVNGHEEVVTFLVDR--KCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADIN 77
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
L + + A I S+V L+ ++ + ++ TPL+ +I+ +
Sbjct: 78 L-----VDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIV 132
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA-NC 222
+ LL N +++ TA+ AV H EI+ ML+++ + D T A C
Sbjct: 133 EFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTC 192
Query: 223 ---HDHQVIIEILKK 234
H H+ I+E ++K
Sbjct: 193 GFHHIHEQIMEYIRK 207
Score = 35.9 bits (79), Expect = 0.22
Identities = 15/54 (27%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 171 VNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-LLEIANCH 223
+N+ ++D TA+ WA + E++ L+++ +L +D +RT L++ CH
Sbjct: 8 INLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCH 61
>AL157387-3|CAH71320.1| 1341|Homo sapiens breast cancer antigen
NY-BR-1 protein.
Length = 1341
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 8/173 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTI 126
N NI+ T L AC + +++V +L+++ + L + TP+M A +
Sbjct: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQ---CHQEAC 65
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+I LID +N+ D YG T L A+ S ++V KLL IE+ ++ T +
Sbjct: 66 ANI---LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLL 122
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
++ +I+E L+ K A V+K T L +A CH I+ +L + N+D
Sbjct: 123 SITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQ-NVD 174
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 86/195 (44%), Gaps = 11/195 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A +NG+ + V L++ K ++ TPLM A Q+ L++ AD N
Sbjct: 20 ALHWACVNGHEEVVTFLVDR--KCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADIN 77
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
L + + A I S+V L+ ++ + ++ TPL+ +I+ +
Sbjct: 78 L-----VDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIV 132
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA-NC 222
+ LL N +++ TA+ AV H EI+ ML+++ + D T A C
Sbjct: 133 EFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTC 192
Query: 223 ---HDHQVIIEILKK 234
H H+ I+E ++K
Sbjct: 193 GFHHIHEQIMEYIRK 207
Score = 35.9 bits (79), Expect = 0.22
Identities = 15/54 (27%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 171 VNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-LLEIANCH 223
+N+ ++D TA+ WA + E++ L+++ +L +D +RT L++ CH
Sbjct: 8 INLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCH 61
>AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein.
Length = 784
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/131 (27%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ N N+ +R G TPL A+ V + LL ++++ +D+ WTA+ +A +
Sbjct: 457 LLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGD 516
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLDDDHKTDENSYLN 251
+L+EK A + EVD RT + +A H + I+ I L++ +++ K +++L
Sbjct: 517 ESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGK---DAWLP 573
Query: 252 HQLTSWQDYYP 262
+WQ + P
Sbjct: 574 LHYAAWQGHLP 584
Score = 55.6 bits (128), Expect = 3e-07
Identities = 55/232 (23%), Positives = 100/232 (43%), Gaps = 12/232 (5%)
Query: 5 RPAGFSDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNE 64
R +G S DS G +S + + + L +AI++G+ + ++ +
Sbjct: 370 RLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQ 429
Query: 65 LKNNANIKLDSGWTPLMHACFHA-QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSAD 122
+ ++ LDSG L+H A Q++ ++LL +A+PNL + TP+ A
Sbjct: 430 ---DVDLALDSG-ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVER---- 481
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ +V L+ R +N D T L A +G + + LL+ ++ D G T
Sbjct: 482 --RVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 539
Query: 183 AVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
+ A H Q I+ +L+ +G ++ K L A H I+++L K
Sbjct: 540 PMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAK 591
Score = 54.0 bits (124), Expect = 8e-07
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS---DSVTPI 112
E+++ L+ ++ L W PL +A + IV+ LL K ++++ D TP+
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPL 608
Query: 113 MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVN 172
A Y + LID +N+ QTPL A +G + A+ LL
Sbjct: 609 HLAAQRGH------YRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAG 662
Query: 173 IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ G+TA+ A + +++L+E+ A + N+T L +A H H ++E L
Sbjct: 663 KKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEEL 722
Score = 47.6 bits (108), Expect = 7e-05
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Query: 65 LKNNANI-KLD-SGWTPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSA 121
L+ NA++ ++D G TP+ AC H Q+ IV+ LL + D +L D+ P+ A
Sbjct: 524 LEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHL 583
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
I ++ +N G+TPL A G VA+ L+D+ ++ +
Sbjct: 584 ---PIVKLLAK--QPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ 638
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
T + A +L+ +GA V T L +A + H +++L
Sbjct: 639 TPLHVAAETGHTSTARLLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLL 689
>AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specificity
Ser/Thr/Tyr kinase protein.
Length = 784
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/131 (27%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ N N+ +R G TPL A+ V + LL ++++ +D+ WTA+ +A +
Sbjct: 457 LLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGD 516
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLDDDHKTDENSYLN 251
+L+EK A + EVD RT + +A H + I+ I L++ +++ K +++L
Sbjct: 517 ESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGK---DAWLP 573
Query: 252 HQLTSWQDYYP 262
+WQ + P
Sbjct: 574 LHYAAWQGHLP 584
Score = 55.6 bits (128), Expect = 3e-07
Identities = 55/232 (23%), Positives = 100/232 (43%), Gaps = 12/232 (5%)
Query: 5 RPAGFSDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNE 64
R +G S DS G +S + + + L +AI++G+ + ++ +
Sbjct: 370 RLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQ 429
Query: 65 LKNNANIKLDSGWTPLMHACFHA-QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSAD 122
+ ++ LDSG L+H A Q++ ++LL +A+PNL + TP+ A
Sbjct: 430 ---DVDLALDSG-ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVER---- 481
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ +V L+ R +N D T L A +G + + LL+ ++ D G T
Sbjct: 482 --RVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 539
Query: 183 AVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
+ A H Q I+ +L+ +G ++ K L A H I+++L K
Sbjct: 540 PMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAK 591
Score = 55.6 bits (128), Expect = 3e-07
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS---DSVTPI 112
E+++ L+ ++ L W PL +A + IV+ LL K ++++ D TP+
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPL 608
Query: 113 MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVN 172
A Y + LID +N+ QTPL A +G + A+ LL
Sbjct: 609 HLAAQRGH------YRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAG 662
Query: 173 IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E G+TA+ A + +++L+E+ A + N+T L +A H H ++E L
Sbjct: 663 KEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEEL 722
Score = 47.6 bits (108), Expect = 7e-05
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Query: 65 LKNNANI-KLD-SGWTPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSA 121
L+ NA++ ++D G TP+ AC H Q+ IV+ LL + D +L D+ P+ A
Sbjct: 524 LEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHL 583
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
I ++ +N G+TPL A G VA+ L+D+ ++ +
Sbjct: 584 ---PIVKLLAK--QPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ 638
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
T + A +L+ +GA V T L +A + H +++L
Sbjct: 639 TPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLL 689
>D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein.
Length = 226
Score = 62.9 bits (146), Expect = 2e-09
Identities = 52/192 (27%), Positives = 91/192 (47%), Gaps = 9/192 (4%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
D S + + AL A G+ + VE L+ +L N K D+GW+PL A +D
Sbjct: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLL--QLGVPVNDKDDAGWSPLHIAASAGRD 86
Query: 90 KIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+IV+ LL K A N ++ + TP+ A S + + I L++ + D Y
Sbjct: 87 EIVKALLGKGAQVNAVNQNGCTPLHYAASKNR------HEIAVMLLEGGANPDAKDHYEA 140
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T + RA + G + + LL + + ++D G T + A + E ++L+ +GA +
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYI 200
Query: 209 VDKSNRTLLEIA 220
+K +T L++A
Sbjct: 201 ENKEEKTPLQVA 212
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/149 (29%), Positives = 64/149 (42%), Gaps = 9/149 (6%)
Query: 95 LLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L +K DS T + ACS + IV L+ +N D G +PL A
Sbjct: 27 LADKSLATRTDQDSRTALHWACSAGHTE------IVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
S+GR + + LL + +Q+G T + +A N+ EI ML+E GA D
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 215 TLLEIANCHDHQVIIEIL---KKSLNLDD 240
T + A + +I IL K S N+ D
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQD 169
>CR769776-11|CAI95383.1| 823|Homo sapiens ankyrin repeat domain 20
family, member A4 protein.
Length = 823
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/107 (31%), Positives = 60/107 (56%), Gaps = 1/107 (0%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L++R C +++ D+ +TPL++A+ A A LL+ N ++D +G TA+ +AV
Sbjct: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRT-LLEIANCHDHQVIIEILKK 234
+ + E L+ GA + +DK N T LL C +++ +LKK
Sbjct: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKK 188
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/131 (31%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L++ N+ D YG T L A+ S ++A+KLL +IE D+ T + +A+ +
Sbjct: 119 LLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKK 178
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD----DDHKTDENS 248
+++E L++K A VD+ R+ L +A +D I+ IL K N+D D D
Sbjct: 179 EKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQ-NIDVFAQDMCGRDAED 237
Query: 249 Y-LNHQLTSWQ 258
Y ++H LT Q
Sbjct: 238 YAISHHLTKIQ 248
Score = 44.4 bits (100), Expect = 6e-04
Identities = 54/223 (24%), Positives = 99/223 (44%), Gaps = 14/223 (6%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A +G+++ V L+N + + + K + TPL+ A ++ LLE
Sbjct: 65 KQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENR--TPLIQAVHCQEEACAVILLEH 122
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
A+PNL I + A S+ L+ + D+ TPL+ AI
Sbjct: 123 GANPNLKD-----IYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICK 177
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ + + LL + + D+ +A+ AV+++ P I+ +L+++ + D R +
Sbjct: 178 KEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAED 237
Query: 219 IANCHD----HQVIIEILKKSLNLD--DDHKTDENSY-LNHQL 254
A H Q I+E KK L + D +DE++ + H+L
Sbjct: 238 YAISHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHEL 280
Score = 35.9 bits (79), Expect = 0.22
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L R+ L+ D+ +T L A +SG V V L++ + I++ D+ T + AVH +
Sbjct: 53 LARRSGELDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQE 112
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIA 220
+L+E GA D T L A
Sbjct: 113 EACAVILLEHGANPNLKDIYGNTALHYA 140
Score = 31.5 bits (68), Expect = 4.8
Identities = 19/87 (21%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
Query: 153 RAISSGRVAVAQKLLDMQVN-IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
RA G A ++ L + ++ D+ TA+ A +++ +L+ + ++ DK
Sbjct: 39 RAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDK 98
Query: 212 SNRT-LLEIANCHDHQVIIEILKKSLN 237
NRT L++ +C + + +L+ N
Sbjct: 99 ENRTPLIQAVHCQEEACAVILLEHGAN 125
>BX649567-2|CAH71137.1| 823|Homo sapiens ankyrin repeat domain 20
family, member A3 protein.
Length = 823
Score = 62.9 bits (146), Expect = 2e-09
Identities = 34/107 (31%), Positives = 60/107 (56%), Gaps = 1/107 (0%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L++R C +++ D+ +TPL++A+ A A LL+ N ++D +G TA+ +AV
Sbjct: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRT-LLEIANCHDHQVIIEILKK 234
+ + E L+ GA + +DK N T LL C +++ +LKK
Sbjct: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKK 188
Score = 55.6 bits (128), Expect = 3e-07
Identities = 41/131 (31%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L++ N+ D YG T L A+ S ++A+KLL +IE D+ T + +A+ +
Sbjct: 119 LLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKK 178
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD----DDHKTDENS 248
+++E L++K A VD+ R+ L +A +D I+ IL K N+D D D
Sbjct: 179 EKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQ-NIDVFAQDMCGRDAED 237
Query: 249 Y-LNHQLTSWQ 258
Y ++H LT Q
Sbjct: 238 YAISHHLTKIQ 248
Score = 44.4 bits (100), Expect = 6e-04
Identities = 54/223 (24%), Positives = 99/223 (44%), Gaps = 14/223 (6%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A +G+++ V L+N + + + K + TPL+ A ++ LLE
Sbjct: 65 KQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENR--TPLIQAVHCQEEACAVILLEH 122
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
A+PNL I + A S+ L+ + D+ TPL+ AI
Sbjct: 123 GANPNLKD-----IYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICK 177
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ + + LL + + D+ +A+ AV+++ P I+ +L+++ + D R +
Sbjct: 178 KEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAED 237
Query: 219 IANCHD----HQVIIEILKKSLNLD--DDHKTDENSY-LNHQL 254
A H Q I+E KK L + D +DE++ + H+L
Sbjct: 238 YAISHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHEL 280
Score = 35.9 bits (79), Expect = 0.22
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L R+ L+ D+ +T L A +SG V V L++ + I++ D+ T + AVH +
Sbjct: 53 LARRSGDLDALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQE 112
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIA 220
+L+E GA D T L A
Sbjct: 113 EACAVILLEHGANPNLKDIYGNTALHYA 140
Score = 31.9 bits (69), Expect = 3.6
Identities = 19/87 (21%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 153 RAISSGRVAVAQKLLDMQV-NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
RA G A ++ L + +++ D+ TA+ A +++ +L+ + ++ DK
Sbjct: 39 RAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDK 98
Query: 212 SNRT-LLEIANCHDHQVIIEILKKSLN 237
NRT L++ +C + + +L+ N
Sbjct: 99 ENRTPLIQAVHCQEEACAVILLEHGAN 125
>BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 62.9 bits (146), Expect = 2e-09
Identities = 52/192 (27%), Positives = 91/192 (47%), Gaps = 9/192 (4%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
D S + + AL A G+ + VE L+ +L N K D+GW+PL A +D
Sbjct: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLL--QLGVPVNDKDDAGWSPLHIAASAGRD 86
Query: 90 KIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+IV+ LL K A N ++ + TP+ A S + + I L++ + D Y
Sbjct: 87 EIVKALLGKGAQVNAVNQNGCTPLHYAASKNR------HEIAVMLLEGGANPDAKDHYEA 140
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T + RA + G + + LL + + ++D G T + A + E ++L+ +GA +
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYI 200
Query: 209 VDKSNRTLLEIA 220
+K +T L++A
Sbjct: 201 ENKEEKTPLQVA 212
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/149 (29%), Positives = 64/149 (42%), Gaps = 9/149 (6%)
Query: 95 LLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L +K DS T + ACS + IV L+ +N D G +PL A
Sbjct: 27 LADKSLATRTDQDSRTALHWACSAGHTE------IVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
S+GR + + LL + +Q+G T + +A N+ EI ML+E GA D
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 215 TLLEIANCHDHQVIIEIL---KKSLNLDD 240
T + A + +I IL K S N+ D
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQD 169
>AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 62.9 bits (146), Expect = 2e-09
Identities = 52/192 (27%), Positives = 91/192 (47%), Gaps = 9/192 (4%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
D S + + AL A G+ + VE L+ +L N K D+GW+PL A +D
Sbjct: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLL--QLGVPVNDKDDAGWSPLHIAASAGRD 86
Query: 90 KIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+IV+ LL K A N ++ + TP+ A S + + I L++ + D Y
Sbjct: 87 EIVKALLGKGAQVNAVNQNGCTPLHYAASKNR------HEIAVMLLEGGANPDAKDHYEA 140
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T + RA + G + + LL + + ++D G T + A + E ++L+ +GA +
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYI 200
Query: 209 VDKSNRTLLEIA 220
+K +T L++A
Sbjct: 201 ENKEEKTPLQVA 212
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/149 (29%), Positives = 64/149 (42%), Gaps = 9/149 (6%)
Query: 95 LLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L +K DS T + ACS + IV L+ +N D G +PL A
Sbjct: 27 LADKSLATRTDQDSRTALHWACSAGHTE------IVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
S+GR + + LL + +Q+G T + +A N+ EI ML+E GA D
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 215 TLLEIANCHDHQVIIEIL---KKSLNLDD 240
T + A + +I IL K S N+ D
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQD 169
>AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated
transcript 8 BAT8 isoform a variant protein.
Length = 1031
Score = 62.9 bits (146), Expect = 2e-09
Identities = 46/176 (26%), Positives = 78/176 (44%), Gaps = 8/176 (4%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHS 106
++ G ++ V ++ + L N S TPL A +I LL+ A+ N +
Sbjct: 471 SVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDK 530
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
TP+M A N+ + + ++ R + + G T L A G + + L
Sbjct: 531 QQRTPLMEAVVNNHLE------VARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 584
Query: 167 LDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
L QV++ +D GWT + WA H E++ ML+ +GA +T D + L+E N
Sbjct: 585 LSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNVSERLVEEEN 640
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 36 SSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYL 95
S ++ L A GN++ V L++ + + N + GWTP++ A H ++++ L
Sbjct: 560 SKEEDGSTCLHHAAKIGNLEMVSLLLSTG-QVDVNAQDSGGWTPIIWAAEHKHIEVIRML 618
Query: 96 LEKDADPNLHSDSVTPIMAACSNSS---ADNDTIYSIVCNLIDRNCILNIGDRYGQTPLM 152
L + AD L +D+V+ + N A +I L++ C L+ + +G TPL
Sbjct: 619 LTRGADVTL-TDNVSERLVEEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLH 677
Query: 153 RAISSGRVAVAQKLLDMQVNIEMRDQHGWTA 183
A L N E+R++ G TA
Sbjct: 678 IAARESYHDCVLLFLSRGANPELRNKEGDTA 708
Score = 32.3 bits (70), Expect = 2.7
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 9/171 (5%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ L EA++N +++ ++ K + G T L HA ++V LL
Sbjct: 530 KQQRTPLMEAVVNNHLEVARYMVQRG--GCVYSKEEDGSTCLHHAAKIGNLEMVSLLLST 587
Query: 99 -DADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTP---LMR 153
D N S TPI+ A + + I ++ D N+ +R + L
Sbjct: 588 GQVDVNAQDSGGWTPIIWAAEHKHIE--VIRMLLTRGADVTLTDNVSERLVEEENICLHW 645
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA 204
A +G A+A+ LL+ + ++ + HG T + A + + + + + +GA
Sbjct: 646 ASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGA 696
>AB095935-1|BAC23111.1| 996|Homo sapiens KIAA2015 protein protein.
Length = 996
Score = 62.9 bits (146), Expect = 2e-09
Identities = 51/190 (26%), Positives = 94/190 (49%), Gaps = 10/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKN-NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ A I G+ +VE + ++ +A + D T L AC H + ++V LL + +
Sbjct: 42 IHRAAIKGDAAEVERCLTRRFRDLDARDRKDR--TVLHLACAHGRVQVVTLLLHRRCQID 99
Query: 104 LHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ + TP+M A + + +IV L++ NI D YG T L A+ + ++
Sbjct: 100 ICDRLNRTPLMKAVHSQ----EEACAIV--LLECGANPNIKDIYGNTALHYAVYNKGTSL 153
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A++LL NIE ++ G T + +A++ + ++E L++ A + VD RT L +A
Sbjct: 154 AERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQ 213
Query: 223 HDHQVIIEIL 232
H+ I+ +L
Sbjct: 214 HNLSSIVTLL 223
Score = 62.9 bits (146), Expect = 2e-09
Identities = 55/211 (26%), Positives = 97/211 (45%), Gaps = 10/211 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K L A +G ++ V L++ + + +L+ TPLM A ++ LLE
Sbjct: 70 RKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNR--TPLMKAVHSQEEACAIVLLEC 127
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
A+PN+ T + A N S+ L+ + + ++ G TPL+ AI+S
Sbjct: 128 GANPNIKDIYGNTALHYAVYNKGT------SLAERLLSHHANIEALNKEGNTPLLFAINS 181
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
R + + LL Q NI D TA+ AV HN I+ +L+++ R++ D +T
Sbjct: 182 RRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAE 241
Query: 218 EIANCHD-HQVIIEILKKSLNLDDDHKTDEN 247
+ A C D + +IL+ + +H ++N
Sbjct: 242 DYALCSDLRSIRQQILEHKNKMLKNHLRNDN 272
>AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit p28
protein.
Length = 226
Score = 62.9 bits (146), Expect = 2e-09
Identities = 52/192 (27%), Positives = 91/192 (47%), Gaps = 9/192 (4%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
D S + + AL A G+ + VE L+ +L N K D+GW+PL A +D
Sbjct: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLL--QLGVPVNDKDDAGWSPLHIAASAGRD 86
Query: 90 KIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+IV+ LL K A N ++ + TP+ A S + + I L++ + D Y
Sbjct: 87 EIVKALLGKGAQVNAVNQNGCTPLHYAASKNR------HEIAVMLLEGGANPDAKDHYEA 140
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T + RA + G + + LL + + ++D G T + A + E ++L+ +GA +
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYI 200
Query: 209 VDKSNRTLLEIA 220
+K +T L++A
Sbjct: 201 ENKEEKTPLQVA 212
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/149 (29%), Positives = 64/149 (42%), Gaps = 9/149 (6%)
Query: 95 LLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L +K DS T + ACS + IV L+ +N D G +PL A
Sbjct: 27 LADKSLATRTDQDSRTALHWACSAGHTE------IVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
S+GR + + LL + +Q+G T + +A N+ EI ML+E GA D
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 215 TLLEIANCHDHQVIIEIL---KKSLNLDD 240
T + A + +I IL K S N+ D
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQD 169
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 62.5 bits (145), Expect = 2e-09
Identities = 49/201 (24%), Positives = 87/201 (43%), Gaps = 9/201 (4%)
Query: 35 ISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQY 94
IS K+ E L A +G + L E N NIK G TPL+ A IV+
Sbjct: 473 ISRTKEEETPLHCAAWHGYYSVAKALC--EAGCNVNIKNREGETPLLTASARGYHDIVEC 530
Query: 95 LLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMR 153
L E AD N D + A + ++ L+ + C ++ DR+G TPL
Sbjct: 531 LAEHGADLNACDKDGHIALHLAVRRCQME------VIKTLLSQGCFVDYQDRHGNTPLHV 584
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSN 213
A G + + L + N+++ +++G T + A ++ +++ L GA + +
Sbjct: 585 ACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDG 644
Query: 214 RTLLEIANCHDHQVIIEILKK 234
+T ++A H+ + +L +
Sbjct: 645 KTAEDLARSEQHEHVAGLLAR 665
Score = 56.8 bits (131), Expect = 1e-07
Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 3/119 (2%)
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
YS+ L + C +NI +R G+TPL+ A + G + + L + ++ D+ G A+
Sbjct: 492 YSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHL 551
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQ--VIIEILKKSLNLDDDHK 243
AV Q E+++ L+ +G + D+ T L +A C D +++ + + + NLD +K
Sbjct: 552 AVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA-CKDGNMPIVVALCEANCNLDISNK 609
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 3/126 (2%)
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N +N +++G PL+ A G + + Q L+ I+++D+ G AV+WA H + L
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLDDDHKTDENSYLNHQLT 255
+ L E L DKS L +A + H + ++ S + +E + L+
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEEETPLH--CA 486
Query: 256 SWQDYY 261
+W YY
Sbjct: 487 AWHGYY 492
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 10/184 (5%)
Query: 63 NELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSA 121
+E K ++K SG L A + + Q L ++PN+ + TP+ A +
Sbjct: 432 SENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHG-- 489
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
YS+ L + C +NI +R G+TPL+ A + G + + L + ++ D+ G
Sbjct: 490 ----YYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQ--VIIEILKKSLNLD 239
A+ AV Q E+++ L+ +G + D+ T L +A C D +++ + + + NLD
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA-CKDGNMPIVVALCEANCNLD 604
Query: 240 DDHK 243
+K
Sbjct: 605 ISNK 608
Score = 61.3 bits (142), Expect = 5e-09
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N NIK G TPL+ A IV+ L E AD N D + A +
Sbjct: 503 NVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME---- 558
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ L+ + C ++ DR+G TPL A G + + L + N+++ +++G T +
Sbjct: 559 --VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHL 616
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A ++ +++ L GA + + +T ++A H+ + +L +
Sbjct: 617 AANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 664
Score = 57.2 bits (132), Expect = 8e-08
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N +N +++G PL+ A G + + Q L+ I+++D+ G AV+WA H + L
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNHQLTS 256
+ L E L DKS L +A + H + ++L + + +E + L+ +
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLH--CAA 486
Query: 257 WQDYY 261
W YY
Sbjct: 487 WHGYY 491
>CR545463-1|CAM28350.1| 545|Homo sapiens protein expressed in
prostate, ovary, testis, and8) pseudogene protein.
Length = 545
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 6/182 (3%)
Query: 58 EDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACS 117
+DLI + N K T L A + ++V+ LL++ N+ + +
Sbjct: 192 KDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAV 251
Query: 118 NSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRD 177
D + L++ NI D YG T L AI + +A+ LL +IE ++
Sbjct: 252 QCQEDECALM-----LLEHGTDPNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKN 306
Query: 178 QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN 237
+HG T + VH + ++++ LI+K A L +D+ RT L +A C I+ +L + N
Sbjct: 307 KHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQ-N 365
Query: 238 LD 239
+D
Sbjct: 366 ID 367
Score = 56.8 bits (131), Expect = 1e-07
Identities = 49/194 (25%), Positives = 88/194 (45%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + NI + T L A +D+ LLE
Sbjct: 208 KQKRTALHLASANGNSEVVKLLLDRRCQ--LNILDNKKRTALTKAVQCQEDECALMLLEH 265
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
DPN+ + A + + D + + L + + +++G TPL+ +
Sbjct: 266 GTDPNIPDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKHGLTPLLLGVHEQ 320
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 321 KQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTARE 380
Query: 219 IANCHDHQVIIEIL 232
A H VI ++L
Sbjct: 381 YAVSSRHNVICQLL 394
Score = 35.9 bits (79), Expect = 0.22
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 309 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVSLL 361
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + Q L D
Sbjct: 362 LEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSD 396
>BC127623-1|AAI27624.1| 458|Homo sapiens ACTBL1 protein protein.
Length = 458
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 6/182 (3%)
Query: 58 EDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACS 117
+DLI + N K T L A + ++V+ LL++ N+ + +
Sbjct: 155 KDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAV 214
Query: 118 NSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRD 177
D + L++ NI D YG T L AI + +A+ LL +IE ++
Sbjct: 215 QCQEDECALM-----LLEHGTDPNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKN 269
Query: 178 QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN 237
+HG T + VH + ++++ LI+K A L +D+ RT L +A C I+ +L + N
Sbjct: 270 KHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQ-N 328
Query: 238 LD 239
+D
Sbjct: 329 ID 330
Score = 57.2 bits (132), Expect = 8e-08
Identities = 49/194 (25%), Positives = 88/194 (45%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + NI + T L A +D+ LLE
Sbjct: 171 KQKRTALHLASANGNSEVVKLLLDRRCQ--LNILDNKKRTALTKAVQCQEDECALMLLEH 228
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
DPN+ + A + + D + + L + + +++G TPL+ +
Sbjct: 229 GTDPNIPDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKHGLTPLLLGVHEQ 283
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 284 KQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTARE 343
Query: 219 IANCHDHQVIIEIL 232
A H VI ++L
Sbjct: 344 YAVSSHHNVICQLL 357
Score = 35.9 bits (79), Expect = 0.22
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVSLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + Q L D
Sbjct: 325 LEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLSD 359
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 10/184 (5%)
Query: 63 NELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSA 121
+E K ++K SG L A + + Q L ++PN+ + TP+ A +
Sbjct: 432 SENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHG-- 489
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
YS+ L + C +NI +R G+TPL+ A + G + + L + ++ D+ G
Sbjct: 490 ----YYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQ--VIIEILKKSLNLD 239
A+ AV Q E+++ L+ +G + D+ T L +A C D +++ + + + NLD
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA-CKDGNMPIVVALCEANCNLD 604
Query: 240 DDHK 243
+K
Sbjct: 605 ISNK 608
Score = 61.3 bits (142), Expect = 5e-09
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N NIK G TPL+ A IV+ L E AD N D + A +
Sbjct: 503 NVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME---- 558
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ L+ + C ++ DR+G TPL A G + + L + N+++ +++G T +
Sbjct: 559 --VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHL 616
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A ++ +++ L GA + + +T ++A H+ + +L +
Sbjct: 617 AANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 664
Score = 57.2 bits (132), Expect = 8e-08
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N +N +++G PL+ A G + + Q L+ I+++D+ G AV+WA H + L
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNHQLTS 256
+ L E L DKS L +A + H + ++L + + +E + L+ +
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLH--CAA 486
Query: 257 WQDYY 261
W YY
Sbjct: 487 WHGYY 491
>AY465172-1|AAS58871.1| 486|Homo sapiens POTE14C protein.
Length = 486
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 6/182 (3%)
Query: 58 EDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACS 117
+DLI + N K T L A + ++V+ LL++ N+ + +
Sbjct: 155 KDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAV 214
Query: 118 NSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRD 177
D + L++ NI D YG T L AI + +A+ LL +IE ++
Sbjct: 215 QCQEDECALM-----LLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKN 269
Query: 178 QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN 237
+HG T + VH + ++++ LI+K A L +D+ RT L +A C I+ +L + N
Sbjct: 270 KHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQ-N 328
Query: 238 LD 239
+D
Sbjct: 329 ID 330
Score = 56.8 bits (131), Expect = 1e-07
Identities = 51/195 (26%), Positives = 89/195 (45%), Gaps = 9/195 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + NI + T L A +D+ LLE
Sbjct: 171 KQKRTALHLASANGNSEVVKLLLDRRCQ--LNILDNKKRTALTKAVQCQEDECALMLLEH 228
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
DPN+ + T + A N D + + L + + +++G TPL+ +
Sbjct: 229 GTDPNIPDEYGNTTLHYAIYNE----DKLMAKALLLYGAD--IESKNKHGLTPLLLGVHE 282
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T
Sbjct: 283 QKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAR 342
Query: 218 EIANCHDHQVIIEIL 232
E A H VI ++L
Sbjct: 343 EYAVSSRHNVICQLL 357
Score = 35.9 bits (79), Expect = 0.22
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVSLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + Q L D
Sbjct: 325 LEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSD 359
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 10/184 (5%)
Query: 63 NELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSA 121
+E K ++K SG L A + + Q L ++PN+ + TP+ A +
Sbjct: 432 SENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHG-- 489
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
YS+ L + C +NI +R G+TPL+ A + G + + L + ++ D+ G
Sbjct: 490 ----YYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQ--VIIEILKKSLNLD 239
A+ AV Q E+++ L+ +G + D+ T L +A C D +++ + + + NLD
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA-CKDGNMPIVVALCEANCNLD 604
Query: 240 DDHK 243
+K
Sbjct: 605 ISNK 608
Score = 61.3 bits (142), Expect = 5e-09
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N NIK G TPL+ A IV+ L E AD N D + A +
Sbjct: 503 NVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME---- 558
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ L+ + C ++ DR+G TPL A G + + L + N+++ +++G T +
Sbjct: 559 --VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHL 616
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A ++ +++ L GA + + +T ++A H+ + +L +
Sbjct: 617 AANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 664
Score = 57.2 bits (132), Expect = 8e-08
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N +N +++G PL+ A G + + Q L+ I+++D+ G AV+WA H + L
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNHQLTS 256
+ L E L DKS L +A + H + ++L + + +E + L+ +
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLH--CAA 486
Query: 257 WQDYY 261
W YY
Sbjct: 487 WHGYY 491
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 10/184 (5%)
Query: 63 NELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSA 121
+E K ++K SG L A + + Q L ++PN+ + TP+ A +
Sbjct: 432 SENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHG-- 489
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
YS+ L + C +NI +R G+TPL+ A + G + + L + ++ D+ G
Sbjct: 490 ----YYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQ--VIIEILKKSLNLD 239
A+ AV Q E+++ L+ +G + D+ T L +A C D +++ + + + NLD
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA-CKDGNMPIVVALCEANCNLD 604
Query: 240 DDHK 243
+K
Sbjct: 605 ISNK 608
Score = 61.3 bits (142), Expect = 5e-09
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N NIK G TPL+ A IV+ L E AD N D + A +
Sbjct: 503 NVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME---- 558
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ L+ + C ++ DR+G TPL A G + + L + N+++ +++G T +
Sbjct: 559 --VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHL 616
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A ++ +++ L GA + + +T ++A H+ + +L +
Sbjct: 617 AANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 664
Score = 57.2 bits (132), Expect = 8e-08
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N +N +++G PL+ A G + + Q L+ I+++D+ G AV+WA H + L
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNHQLTS 256
+ L E L DKS L +A + H + ++L + + +E + L+ +
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLH--CAA 486
Query: 257 WQDYY 261
W YY
Sbjct: 487 WHGYY 491
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 10/184 (5%)
Query: 63 NELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSA 121
+E K ++K SG L A + + Q L ++PN+ + TP+ A +
Sbjct: 432 SENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHG-- 489
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
YS+ L + C +NI +R G+TPL+ A + G + + L + ++ D+ G
Sbjct: 490 ----YYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQ--VIIEILKKSLNLD 239
A+ AV Q E+++ L+ +G + D+ T L +A C D +++ + + + NLD
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA-CKDGNMPIVVALCEANCNLD 604
Query: 240 DDHK 243
+K
Sbjct: 605 ISNK 608
Score = 61.3 bits (142), Expect = 5e-09
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N NIK G TPL+ A IV+ L E AD N D + A +
Sbjct: 503 NVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME---- 558
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ L+ + C ++ DR+G TPL A G + + L + N+++ +++G T +
Sbjct: 559 --VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHL 616
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A ++ +++ L GA + + +T ++A H+ + +L +
Sbjct: 617 AANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 664
Score = 57.2 bits (132), Expect = 8e-08
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N +N +++G PL+ A G + + Q L+ I+++D+ G AV+WA H + L
Sbjct: 369 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 428
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNHQLTS 256
+ L E L DKS L +A + H + ++L + + +E + L+ +
Sbjct: 429 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLH--CAA 486
Query: 257 WQDYY 261
W YY
Sbjct: 487 WHGYY 491
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 10/184 (5%)
Query: 63 NELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSA 121
+E K ++K SG L A + + Q L ++PN+ + TP+ A +
Sbjct: 435 SENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHG-- 492
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
YS+ L + C +NI +R G+TPL+ A + G + + L + ++ D+ G
Sbjct: 493 ----YYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGH 548
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQ--VIIEILKKSLNLD 239
A+ AV Q E+++ L+ +G + D+ T L +A C D +++ + + + NLD
Sbjct: 549 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVA-CKDGNMPIVVALCEANCNLD 607
Query: 240 DDHK 243
+K
Sbjct: 608 ISNK 611
Score = 61.3 bits (142), Expect = 5e-09
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N NIK G TPL+ A IV+ L E AD N D + A +
Sbjct: 506 NVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME---- 561
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ L+ + C ++ DR+G TPL A G + + L + N+++ +++G T +
Sbjct: 562 --VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHL 619
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A ++ +++ L GA + + +T ++A H+ + +L +
Sbjct: 620 AANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 667
Score = 57.2 bits (132), Expect = 8e-08
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N +N +++G PL+ A G + + Q L+ I+++D+ G AV+WA H + L
Sbjct: 372 NYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL 431
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNHQLTS 256
+ L E L DKS L +A + H + ++L + + +E + L+ +
Sbjct: 432 KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLH--CAA 489
Query: 257 WQDYY 261
W YY
Sbjct: 490 WHGYY 494
>BX664727-6|CAI39536.1| 823|Homo sapiens ankyrin repeat domain 20
family, member A2 protein.
Length = 823
Score = 62.1 bits (144), Expect = 3e-09
Identities = 33/106 (31%), Positives = 58/106 (54%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L++R C +++ D+ +TPL++A+ A A LL+ N ++D +G TA+ +AV
Sbjct: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
+ + E L+ GA + +DK N T L A + ++E L K
Sbjct: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLK 187
Score = 54.4 bits (125), Expect = 6e-07
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L++ N+ D YG T L A+ S ++A+KLL +IE D+ T + +A+ +
Sbjct: 119 LLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKK 178
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD----DDHKTDENS 248
+++E L+++ A VD+ R+ L +A +D I+ IL K N+D D D
Sbjct: 179 EKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQ-NIDVFAQDMCGRDAED 237
Query: 249 Y-LNHQLTSWQ 258
Y ++H LT Q
Sbjct: 238 YAISHHLTKIQ 248
Score = 44.4 bits (100), Expect = 6e-04
Identities = 54/223 (24%), Positives = 99/223 (44%), Gaps = 14/223 (6%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A +G+++ V L+N + + + K + TPL+ A ++ LLE
Sbjct: 65 KQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENR--TPLIQAVHCQEEACAVILLEH 122
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
A+PNL I + A S+ L+ + D+ TPL+ AI
Sbjct: 123 GANPNLKD-----IYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICK 177
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ + + LL + + D+ +A+ AV+++ P I+ +L+++ + D R +
Sbjct: 178 KEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAED 237
Query: 219 IANCHD----HQVIIEILKKSLNLD--DDHKTDENSY-LNHQL 254
A H Q I+E KK L + D +DE++ + H+L
Sbjct: 238 YAISHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHEL 280
Score = 35.9 bits (79), Expect = 0.22
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L R+ L+ D+ +T L A +SG V V L++ + I++ D+ T + AVH +
Sbjct: 53 LARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQE 112
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIA 220
+L+E GA D T L A
Sbjct: 113 EACAVILLEHGANPNLKDIYGNTALHYA 140
Score = 31.9 bits (69), Expect = 3.6
Identities = 19/87 (21%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 153 RAISSGRVAVAQKLLDMQV-NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
RA G A ++ L + +++ D+ TA+ A +++ +L+ + ++ DK
Sbjct: 39 RAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDK 98
Query: 212 SNRT-LLEIANCHDHQVIIEILKKSLN 237
NRT L++ +C + + +L+ N
Sbjct: 99 ENRTPLIQAVHCQEEACAVILLEHGAN 125
>AY462874-1|AAS58868.1| 508|Homo sapiens POTE14A protein.
Length = 508
Score = 62.1 bits (144), Expect = 3e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 6/182 (3%)
Query: 58 EDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACS 117
+DLI + N K T L A + ++V+ LL++ N+ + +
Sbjct: 155 KDLIVMLKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAV 214
Query: 118 NSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRD 177
D + L++ NI D YG T L AI + +A+ LL +IE ++
Sbjct: 215 QCREDECALM-----LLEHGTDPNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKN 269
Query: 178 QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN 237
+HG T + VH + ++++ LI+K A L +D+ RT L +A C I+ +L + N
Sbjct: 270 KHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQ-N 328
Query: 238 LD 239
+D
Sbjct: 329 ID 330
Score = 56.8 bits (131), Expect = 1e-07
Identities = 49/194 (25%), Positives = 88/194 (45%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + NI + T L A +D+ LLE
Sbjct: 171 KQKRTALHLASANGNSEVVKLLLDRRCQ--LNILDNKKRTALTKAVQCREDECALMLLEH 228
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
DPN+ + A + + D + + L + + +++G TPL+ +
Sbjct: 229 GTDPNIPDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKHGLTPLLLGVHEQ 283
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 284 KQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTARE 343
Query: 219 IANCHDHQVIIEIL 232
A H VI ++L
Sbjct: 344 YAVSSRHNVICQLL 357
Score = 35.9 bits (79), Expect = 0.22
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVSLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + Q L D
Sbjct: 325 LEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSD 359
>AY462873-1|AAS58867.1| 376|Homo sapiens POTE2C protein.
Length = 376
Score = 62.1 bits (144), Expect = 3e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 6/182 (3%)
Query: 58 EDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACS 117
+DLI + N K T L A + ++V+ LL++ N+ + +
Sbjct: 155 KDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAV 214
Query: 118 NSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRD 177
D + L++ NI D YG T L AI + +A+ LL +IE ++
Sbjct: 215 QCQEDECALM-----LLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKN 269
Query: 178 QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN 237
+HG T + VH + ++++ LI+K A L +D+ RT L +A C I+ +L + N
Sbjct: 270 KHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQ-N 328
Query: 238 LD 239
+D
Sbjct: 329 ID 330
Score = 58.8 bits (136), Expect = 3e-08
Identities = 50/195 (25%), Positives = 90/195 (46%), Gaps = 9/195 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ LLE
Sbjct: 171 KQKRTALHLASANGNSEVVKLLLDRRCQ--LNVLDNKKRTALIKAVQCQEDECALMLLEH 228
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
DPN+ + T + A N D + + L + + +++G TPL+ +
Sbjct: 229 GTDPNIPDEYGNTTLHYAIYNE----DKLMAKALLLYGAD--IESKNKHGLTPLLLGVHE 282
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T
Sbjct: 283 QKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAR 342
Query: 218 EIANCHDHQVIIEIL 232
E A H VI ++L
Sbjct: 343 EYAGSSHHHVICQLL 357
Score = 33.1 bits (72), Expect = 1.6
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVSLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A SS + Q L D
Sbjct: 325 LEQNIDVSSQDLSGQTAREYAGSSHHHVICQLLSD 359
>AY462871-1|AAS58865.1| 712|Homo sapiens POTE2A protein.
Length = 712
Score = 62.1 bits (144), Expect = 3e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 6/182 (3%)
Query: 58 EDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACS 117
+DLI + N K T L A + ++V+ LL++ N+ + +
Sbjct: 155 KDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAV 214
Query: 118 NSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRD 177
D + L++ NI D YG T L AI + +A+ LL +IE ++
Sbjct: 215 QCQEDECALM-----LLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKN 269
Query: 178 QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN 237
+HG T + VH + ++++ LI+K A L +D+ RT L +A C I+ +L + N
Sbjct: 270 KHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQ-N 328
Query: 238 LD 239
+D
Sbjct: 329 ID 330
Score = 58.4 bits (135), Expect = 4e-08
Identities = 59/247 (23%), Positives = 111/247 (44%), Gaps = 19/247 (7%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ LLE
Sbjct: 171 KQKRTALHLASANGNSEVVKLLLDRRCQ--LNVLDNKKRTALIKAVQCQEDECALMLLEH 228
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
DPN+ + T + A N D + + L + + +++G TPL+ +
Sbjct: 229 GTDPNIPDEYGNTTLHYAIYNE----DKLMAKALLLYGAD--IESKNKHGLTPLLLGVHE 282
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T
Sbjct: 283 QKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAR 342
Query: 218 EIANCHDHQVIIEIL-----KKSLNLDDDHKTDENSYLNHQLTSWQD--YYPGIEKNERP 270
E A H VI ++L K+ L + ++ E +LTS ++ + G E ++
Sbjct: 343 EYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDL---KLTSEEESQRFKGSENSQPE 399
Query: 271 NYKNEIQ 277
E++
Sbjct: 400 KMSQELE 406
>AY462868-1|AAS58862.1| 376|Homo sapiens POTE2D protein.
Length = 376
Score = 62.1 bits (144), Expect = 3e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 6/182 (3%)
Query: 58 EDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACS 117
+DLI + N K T L A + ++V+ LL++ N+ + +
Sbjct: 155 KDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAV 214
Query: 118 NSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRD 177
D + L++ NI D YG T L AI + +A+ LL +IE ++
Sbjct: 215 QCQEDECALM-----LLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKN 269
Query: 178 QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLN 237
+HG T + VH + ++++ LI+K A L +D+ RT L +A C I+ +L + N
Sbjct: 270 KHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQ-N 328
Query: 238 LD 239
+D
Sbjct: 329 ID 330
Score = 57.6 bits (133), Expect = 6e-08
Identities = 50/195 (25%), Positives = 90/195 (46%), Gaps = 9/195 (4%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ LLE
Sbjct: 171 KQKRTALHLASANGNSEVVKLLLDRRCQ--LNVLDNKKRTALIKAVQCQEDECALMLLEH 228
Query: 99 DADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
DPN+ + T + A N D + + L + + +++G TPL+ +
Sbjct: 229 GTDPNIPDEYGNTTLHYAIYNE----DKLMAKALLLYGAD--IESKNKHGLTPLLLGVHE 282
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T
Sbjct: 283 QKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAR 342
Query: 218 EIANCHDHQVIIEIL 232
E A H VI ++L
Sbjct: 343 EYAVSSHHHVICQLL 357
Score = 35.9 bits (79), Expect = 0.22
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVSLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + Q L D
Sbjct: 325 LEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSD 359
>AL773545-6|CAI12706.1| 823|Homo sapiens ankyrin repeat domain 20
family, member A2 protein.
Length = 823
Score = 62.1 bits (144), Expect = 3e-09
Identities = 33/106 (31%), Positives = 58/106 (54%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L++R C +++ D+ +TPL++A+ A A LL+ N ++D +G TA+ +AV
Sbjct: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
+ + E L+ GA + +DK N T L A + ++E L K
Sbjct: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLK 187
Score = 54.4 bits (125), Expect = 6e-07
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L++ N+ D YG T L A+ S ++A+KLL +IE D+ T + +A+ +
Sbjct: 119 LLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKK 178
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD----DDHKTDENS 248
+++E L+++ A VD+ R+ L +A +D I+ IL K N+D D D
Sbjct: 179 EKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQ-NIDVFAQDMCGRDAED 237
Query: 249 Y-LNHQLTSWQ 258
Y ++H LT Q
Sbjct: 238 YAISHHLTKIQ 248
Score = 44.4 bits (100), Expect = 6e-04
Identities = 54/223 (24%), Positives = 99/223 (44%), Gaps = 14/223 (6%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A +G+++ V L+N + + + K + TPL+ A ++ LLE
Sbjct: 65 KQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENR--TPLIQAVHCQEEACAVILLEH 122
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
A+PNL I + A S+ L+ + D+ TPL+ AI
Sbjct: 123 GANPNLKD-----IYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICK 177
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ + + LL + + D+ +A+ AV+++ P I+ +L+++ + D R +
Sbjct: 178 KEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAED 237
Query: 219 IANCHD----HQVIIEILKKSLNLD--DDHKTDENSY-LNHQL 254
A H Q I+E KK L + D +DE++ + H+L
Sbjct: 238 YAISHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHEL 280
Score = 35.9 bits (79), Expect = 0.22
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L R+ L+ D+ +T L A +SG V V L++ + I++ D+ T + AVH +
Sbjct: 53 LARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQE 112
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIA 220
+L+E GA D T L A
Sbjct: 113 EACAVILLEHGANPNLKDIYGNTALHYA 140
Score = 31.9 bits (69), Expect = 3.6
Identities = 19/87 (21%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 153 RAISSGRVAVAQKLLDMQV-NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
RA G A ++ L + +++ D+ TA+ A +++ +L+ + ++ DK
Sbjct: 39 RAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDK 98
Query: 212 SNRT-LLEIANCHDHQVIIEILKKSLN 237
NRT L++ +C + + +L+ N
Sbjct: 99 ENRTPLIQAVHCQEEACAVILLEHGAN 125
>AL513478-3|CAH72532.1| 823|Homo sapiens ankyrin repeat domain 20
family, member A1 protein.
Length = 823
Score = 62.1 bits (144), Expect = 3e-09
Identities = 33/106 (31%), Positives = 58/106 (54%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L++R C +++ D+ +TPL++A+ A A LL+ N ++D +G TA+ +AV
Sbjct: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
+ + E L+ GA + +DK N T L A + ++E L K
Sbjct: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLK 187
Score = 54.4 bits (125), Expect = 6e-07
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L++ N+ D YG T L A+ S ++A+KLL +IE D+ T + +A+ +
Sbjct: 119 LLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKK 178
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD----DDHKTDENS 248
+++E L+++ A VD+ R+ L +A +D I+ IL K N+D D D
Sbjct: 179 EKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQ-NIDVFAQDMCGRDAED 237
Query: 249 Y-LNHQLTSWQ 258
Y ++H LT Q
Sbjct: 238 YAISHHLTKIQ 248
Score = 44.4 bits (100), Expect = 6e-04
Identities = 54/223 (24%), Positives = 99/223 (44%), Gaps = 14/223 (6%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A +G+++ V L+N + + + K + TPL+ A ++ LLE
Sbjct: 65 KQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENR--TPLIQAVHCQEEACAVILLEH 122
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
A+PNL I + A S+ L+ + D+ TPL+ AI
Sbjct: 123 GANPNLKD-----IYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICK 177
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ + + LL + + D+ +A+ AV+++ P I+ +L+++ + D R +
Sbjct: 178 KEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAED 237
Query: 219 IANCHD----HQVIIEILKKSLNLD--DDHKTDENSY-LNHQL 254
A H Q I+E KK L + D +DE++ + H+L
Sbjct: 238 YAISHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHEL 280
Score = 35.9 bits (79), Expect = 0.22
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L R+ L+ D+ +T L A +SG V V L++ + I++ D+ T + AVH +
Sbjct: 53 LARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQE 112
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIA 220
+L+E GA D T L A
Sbjct: 113 EACAVILLEHGANPNLKDIYGNTALHYA 140
Score = 31.9 bits (69), Expect = 3.6
Identities = 19/87 (21%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 153 RAISSGRVAVAQKLLDMQV-NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
RA G A ++ L + +++ D+ TA+ A +++ +L+ + ++ DK
Sbjct: 39 RAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDK 98
Query: 212 SNRT-LLEIANCHDHQVIIEILKKSLN 237
NRT L++ +C + + +L+ N
Sbjct: 99 ENRTPLIQAVHCQEEACAVILLEHGAN 125
>AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to
ANKYRIN R. ).
Length = 784
Score = 62.1 bits (144), Expect = 3e-09
Identities = 35/131 (26%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ N N+ +R G TPL A+ V ++LL ++++ +D+ WTA+ +A +
Sbjct: 457 LLLNNANPNLSNRRGSTPLHMAVERRVRGVVERLLARKISVNAKDEDQWTALHFAAQNGD 516
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI-LKKSLNLDDDHKTDENSYLN 251
+L+EK A + EVD T + +A H + I+ I L++ +++ K +++L
Sbjct: 517 ESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQENIVRILLRRGVDVSLQGK---DAWLP 573
Query: 252 HQLTSWQDYYP 262
+WQ + P
Sbjct: 574 LHYAAWQGHLP 584
Score = 57.2 bits (132), Expect = 8e-08
Identities = 55/232 (23%), Positives = 100/232 (43%), Gaps = 12/232 (5%)
Query: 5 RPAGFSDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNE 64
R +G S DS G +S + + + L +AI++G+ + ++ +
Sbjct: 370 RLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQ 429
Query: 65 LKNNANIKLDSGWTPLMHACFHA-QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSAD 122
+ ++ LDSG L+H A Q++ ++LL +A+PNL + TP+ A
Sbjct: 430 ---DVDLALDSG-ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVER---- 481
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ +V L+ R +N D T L A +G + + LL+ ++ D G T
Sbjct: 482 --RVRGVVERLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLT 539
Query: 183 AVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
+ A H Q I+ +L+ +G ++ K L A H I+++L K
Sbjct: 540 PMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAK 591
Score = 55.6 bits (128), Expect = 3e-07
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS---DSVTPI 112
E+++ L+ ++ L W PL +A + IV+ LL K ++++ D TP+
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK-LLAKQPGVSVNAQTLDGRTPL 608
Query: 113 MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVN 172
A Y + LID +N+ QTPL A +G + A+ LL
Sbjct: 609 HLAAQRGH------YRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAG 662
Query: 173 IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E G+TA+ A + +++L+E+ A + N+T L +A H H ++E L
Sbjct: 663 KEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEEL 722
Score = 48.0 bits (109), Expect = 5e-05
Identities = 43/171 (25%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Query: 65 LKNNANI-KLD-SGWTPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSA 121
L+ NA++ ++D G TP+ AC H Q+ IV+ LL + D +L D+ P+ A
Sbjct: 524 LEKNASVNEVDFEGLTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHL 583
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
I ++ +N G+TPL A G VA+ L+D+ ++ +
Sbjct: 584 ---PIVKLLAK--QPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ 638
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
T + A +L+ +GA V T L +A + H +++L
Sbjct: 639 TPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLL 689
>U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein.
Length = 1088
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/158 (29%), Positives = 77/158 (48%), Gaps = 5/158 (3%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
+G+TPL A Q I LLE AD N +VT A + +A + +V L+
Sbjct: 251 NGYTPLHIAAKKNQMDIATTLLEYGADAN----AVTRQGIASVHLAAQEGHV-DMVSLLL 305
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
RN +N+ ++ G TPL A RV VA+ L++ +++ + + G+T + H+ +
Sbjct: 306 GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 365
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
I+ L++ A++ K+ T L A H II +L
Sbjct: 366 IVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 403
Score = 60.5 bits (140), Expect = 9e-09
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A +G + V L+ + + A K D TPL + + IVQ LL++ A
Sbjct: 88 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGAS 145
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
PN + S TP+ + D + L+D L+I + G TPL A G++
Sbjct: 146 PNAATTSGYTPLHLSAREGHED------VAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 199
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA LL + + + G T + A H++ ++ +L+++GA K+ T L IA
Sbjct: 200 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 259
Score = 56.8 bits (131), Expect = 1e-07
Identities = 49/187 (26%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 48 AIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
A G++ V L+++ N N++ G T L A Q ++V+YL++ A +
Sbjct: 61 AAFMGHVNIVSQLMHHGASPNTTNVR---GETALHMAARSGQAEVVRYLVQDGAQVEAKA 117
Query: 107 -DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQK 165
D TP+ + AD IV L+ + N G TPL + G VA
Sbjct: 118 KDDQTPLHISARLGKAD------IVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 171
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD ++ + + G+T + A + + E+ +L++K A KS T L +A +D+
Sbjct: 172 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDN 231
Query: 226 QVIIEIL 232
Q + +L
Sbjct: 232 QKVALLL 238
Score = 52.0 bits (119), Expect = 3e-06
Identities = 43/178 (24%), Positives = 83/178 (46%), Gaps = 9/178 (5%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMA 114
ED+ L + A++ + + G+TPL A + + ++ LL+K A P+ S +TP+
Sbjct: 166 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 225
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
A + DN + + L+D+ + + G TPL A ++ +A LL+ +
Sbjct: 226 A---AHYDNQKVALL---LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADAN 279
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ G +V A +++ +L+ + A + +KS T L +A D + E+L
Sbjct: 280 AVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVL 337
Score = 50.4 bits (115), Expect = 1e-05
Identities = 42/168 (25%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 66 KNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADND 124
K N N K +G+TPL AC + K+++ LL+ A ++S +TPI A
Sbjct: 11 KANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHV--- 67
Query: 125 TIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAV 184
+IV L+ N + G+T L A SG+ V + L+ +E + + T +
Sbjct: 68 ---NIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPL 124
Query: 185 FWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ + +I++ L+++GA S T L ++ H+ + L
Sbjct: 125 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 172
Score = 44.8 bits (101), Expect = 5e-04
Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 91 IVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
+V LL ++A+ NL + S +TP+ A A D + ++ L+++ ++ + G T
Sbjct: 300 MVSLLLGRNANVNLSNKSGLTPLHLA-----AQEDRV-NVAEVLVNQGAHVDAQTKMGYT 353
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL G + + LL + + ++G+T + A I+ +L++ A E+
Sbjct: 354 PLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNEL 413
Query: 210 DKSNRTLLEIANCHDHQVIIEILK 233
+ T L IA + +++ LK
Sbjct: 414 TVNGNTALGIARRLGYISVVDTLK 437
Score = 36.7 bits (81), Expect = 0.13
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ + K NA K +G+TPL A I+ LL+ +A PN
Sbjct: 362 GNIKIVNFLLQHSAKVNAKTK--NGYTPLHQAAQQGHTHIINVLLQNNASPN 411
Score = 35.9 bits (79), Expect = 0.22
Identities = 24/90 (26%), Positives = 37/90 (41%)
Query: 131 CNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHH 190
C+L+D+ N G TPL A R+ V + LL +I+ + G T + A
Sbjct: 5 CDLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFM 64
Query: 191 NQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
I+ L+ GA + T L +A
Sbjct: 65 GHVNIVSQLMHHGASPNTTNVRGETALHMA 94
Score = 35.1 bits (77), Expect = 0.39
Identities = 19/67 (28%), Positives = 36/67 (53%)
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD + N + +G+T + A N+ +++E+L++ GA + V +S T + +A H
Sbjct: 7 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 66
Query: 226 QVIIEIL 232
I+ L
Sbjct: 67 VNIVSQL 73
>U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein.
Length = 4377
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/158 (29%), Positives = 77/158 (48%), Gaps = 5/158 (3%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
+G+TPL A Q I LLE AD N +VT A + +A + +V L+
Sbjct: 630 NGYTPLHIAAKKNQMDIATTLLEYGADAN----AVTRQGIASVHLAAQEGHV-DMVSLLL 684
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
RN +N+ ++ G TPL A RV VA+ L++ +++ + + G+T + H+ +
Sbjct: 685 GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 744
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
I+ L++ A++ K+ T L A H II +L
Sbjct: 745 IVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 782
Score = 60.5 bits (140), Expect = 9e-09
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A +G + V L+ + + A K D TPL + + IVQ LL++ A
Sbjct: 467 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGAS 524
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
PN + S TP+ + D + L+D L+I + G TPL A G++
Sbjct: 525 PNAATTSGYTPLHLSAREGHED------VAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 578
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA LL + + + G T + A H++ ++ +L+++GA K+ T L IA
Sbjct: 579 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 638
Score = 56.8 bits (131), Expect = 1e-07
Identities = 49/187 (26%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 48 AIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
A G++ V L+++ N N++ G T L A Q ++V+YL++ A +
Sbjct: 440 AAFMGHVNIVSQLMHHGASPNTTNVR---GETALHMAARSGQAEVVRYLVQDGAQVEAKA 496
Query: 107 -DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQK 165
D TP+ + AD IV L+ + N G TPL + G VA
Sbjct: 497 KDDQTPLHISARLGKAD------IVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD ++ + + G+T + A + + E+ +L++K A KS T L +A +D+
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDN 610
Query: 226 QVIIEIL 232
Q + +L
Sbjct: 611 QKVALLL 617
Score = 52.0 bits (119), Expect = 3e-06
Identities = 43/178 (24%), Positives = 83/178 (46%), Gaps = 9/178 (5%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMA 114
ED+ L + A++ + + G+TPL A + + ++ LL+K A P+ S +TP+
Sbjct: 545 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 604
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
A + DN + + L+D+ + + G TPL A ++ +A LL+ +
Sbjct: 605 A---AHYDNQKVALL---LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADAN 658
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ G +V A +++ +L+ + A + +KS T L +A D + E+L
Sbjct: 659 AVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVL 716
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/199 (23%), Positives = 88/199 (44%), Gaps = 16/199 (8%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ + V L+ N+ K + P +H D K LL+ D + +
Sbjct: 177 LAVALQQGHDQVVSLLLENDTKGKVRL-------PALHIAARKDDTKAAALLLQNDNNAD 229
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ S S TP+ A + + T+ L++R ++ R TPL A G +
Sbjct: 230 VESKSGFTPLHIAAHYGNINVATL------LLNRAAAVDFTARNDITPLHVASKRGNANM 283
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LLD I+ + + G T + +++EML+++ A + K+ + L +A
Sbjct: 284 VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQ 343
Query: 223 HDHQVIIE-ILKKSLNLDD 240
DH ++ +L+ ++ +DD
Sbjct: 344 GDHLNCVQLLLQHNVPVDD 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/104 (24%), Positives = 51/104 (49%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ R ++ + G T L A +G+ V + L+ N+ + Q+G+T ++ A
Sbjct: 89 VVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAA 148
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
N E+++ L++ GA + + T L +A H ++ +L
Sbjct: 149 QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 192
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/190 (26%), Positives = 88/190 (46%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A GN V+ L++ K +A K G TPL +++V+ LL++ A P L
Sbjct: 272 LHVASKRGNANMVKLLLDRGAKIDA--KTRDGLTPLHCGARSGHEQVVEMLLDRAA-PIL 328
Query: 105 HS--DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++P+ A + D+ + V L+ N ++ T L A G V
Sbjct: 329 SKTKNGLSPLHMA---TQGDH---LNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKV 382
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+ LLD + N + +G+T + A N+ +++E+L++ GA + V +S T + +A
Sbjct: 383 AKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAF 442
Query: 223 HDHQVIIEIL 232
H I+ L
Sbjct: 443 MGHVNIVSQL 452
Score = 44.8 bits (101), Expect = 5e-04
Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 91 IVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
+V LL ++A+ NL + S +TP+ A A D + ++ L+++ ++ + G T
Sbjct: 679 MVSLLLGRNANVNLSNKSGLTPLHLA-----AQEDRV-NVAEVLVNQGAHVDAQTKMGYT 732
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL G + + LL + + ++G+T + A I+ +L++ A E+
Sbjct: 733 PLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNEL 792
Query: 210 DKSNRTLLEIANCHDHQVIIEILK 233
+ T L IA + +++ LK
Sbjct: 793 TVNGNTALGIARRLGYISVVDTLK 816
Score = 43.6 bits (98), Expect = 0.001
Identities = 25/93 (26%), Positives = 47/93 (50%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+NI ++ G L A G V V +LL + N++ + G TA+ A Q E++++L
Sbjct: 67 INICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVL 126
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ GA + ++ T L +A +H +++ L
Sbjct: 127 VTNGANVNAQSQNGFTPLYMAAQENHLEVVKFL 159
Score = 36.7 bits (81), Expect = 0.13
Identities = 44/178 (24%), Positives = 73/178 (41%), Gaps = 13/178 (7%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A G+++ V +L+ E +A K G T L A Q ++V+ L+ A+ N
Sbjct: 77 ALHLASKEGHVEVVSELLQREANVDAATK--KGNTALHIASLAGQAEVVKVLVTNGANVN 134
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
S + TP+ A + + +V L+D ++ G TPL A+ G V
Sbjct: 135 AQSQNGFTPLYMAAQENHLE------VVKFLLDNGASQSLATEDGFTPLAVALQQGHDQV 188
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
LL+ ++R A+ A + + +L++ KS T L IA
Sbjct: 189 VSLLLENDTKGKVR----LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIA 242
Score = 36.7 bits (81), Expect = 0.13
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ + K NA K +G+TPL A I+ LL+ +A PN
Sbjct: 741 GNIKIVNFLLQHSAKVNAKTK--NGYTPLHQAAQQGHTHIINVLLQNNASPN 790
Score = 35.9 bits (79), Expect = 0.22
Identities = 36/183 (19%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Query: 23 EKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMH 82
EK ++ S K + A G+++ D I N + + NI +G L
Sbjct: 23 EKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGV--DINICNQNGLNALHL 80
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI 142
A ++V LL+++A+ + + + S + +V L+ +N
Sbjct: 81 ASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAE-----VVKVLVTNGANVNA 135
Query: 143 GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEK 202
+ G TPL A + V + LLD + + + G+T + A+ +++ +L+E
Sbjct: 136 QSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN 195
Query: 203 GAR 205
+
Sbjct: 196 DTK 198
Score = 35.5 bits (78), Expect = 0.29
Identities = 50/207 (24%), Positives = 87/207 (42%), Gaps = 12/207 (5%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
D ++ + SK L A GN+ L+N + + D TPL A
Sbjct: 225 DNNADVESKSGF-TPLHIAAHYGNINVATLLLNRAAAVDFTARNDI--TPLHVASKRGNA 281
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+V+ LL++ A + + D +TP+ C S +V L+DR + + G
Sbjct: 282 NMVKLLLDRGAKIDAKTRDGLTPLH--CGARSGHEQ----VVEMLLDRAAPILSKTKNGL 335
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
+PL A + Q LL V ++ TA+ A H ++ ++L++K A
Sbjct: 336 SPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNA 395
Query: 209 VDKSNRTLLEIANCHDHQV-IIEILKK 234
+ T L IA C +++ ++E+L K
Sbjct: 396 KALNGFTPLHIA-CKKNRIKVMELLLK 421
Score = 34.7 bits (76), Expect = 0.51
Identities = 19/81 (23%), Positives = 39/81 (48%)
Query: 152 MRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+RA +G + A + V+I + +Q+G A+ A E++ L+++ A + K
Sbjct: 46 LRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATK 105
Query: 212 SNRTLLEIANCHDHQVIIEIL 232
T L IA+ ++++L
Sbjct: 106 KGNTALHIASLAGQAEVVKVL 126
Score = 34.3 bits (75), Expect = 0.68
Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 5/149 (3%)
Query: 72 KLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVC 131
K +G +PL A VQ LL+ N+ D VT + +A Y +
Sbjct: 330 KTKNGLSPLHMATQGDHLNCVQLLLQH----NVPVDDVTNDYLTALHVAAHCGH-YKVAK 384
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
L+D+ N G TPL A R+ V + LL +I+ + G T + A
Sbjct: 385 VLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMG 444
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIA 220
I+ L+ GA + T L +A
Sbjct: 445 HVNIVSQLMHHGASPNTTNVRGETALHMA 473
>AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1
variant protein.
Length = 931
Score = 61.7 bits (143), Expect = 4e-09
Identities = 46/158 (29%), Positives = 77/158 (48%), Gaps = 5/158 (3%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
+G+TPL A Q I LLE AD N +VT A + +A + +V L+
Sbjct: 174 NGYTPLHIAAKKNQMDIATTLLEYGADAN----AVTRQGIASVHLAAQEGHV-DMVSLLL 228
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
RN +N+ ++ G TPL A RV VA+ L++ +++ + + G+T + H+ +
Sbjct: 229 GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 288
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
I+ L++ A++ K+ T L A H II +L
Sbjct: 289 IVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 326
Score = 60.5 bits (140), Expect = 9e-09
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A +G + V L+ + + A K D TPL + + IVQ LL++ A
Sbjct: 11 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGAS 68
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
PN + S TP+ + D + L+D L+I + G TPL A G++
Sbjct: 69 PNAATTSGYTPLHLSAREGHED------VAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 122
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA LL + + + G T + A H++ ++ +L+++GA K+ T L IA
Sbjct: 123 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 182
Score = 54.8 bits (126), Expect = 4e-07
Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 7/158 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLI 134
G T L A Q ++V+YL++ A + D TP+ + AD IV L+
Sbjct: 10 GETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKAD------IVQQLL 63
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+ N G TPL + G VA LLD ++ + + G+T + A + + E
Sbjct: 64 QQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLE 123
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ +L++K A KS T L +A +D+Q + +L
Sbjct: 124 VANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLL 161
Score = 52.0 bits (119), Expect = 3e-06
Identities = 43/178 (24%), Positives = 83/178 (46%), Gaps = 9/178 (5%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMA 114
ED+ L + A++ + + G+TPL A + + ++ LL+K A P+ S +TP+
Sbjct: 89 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 148
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
A + DN + + L+D+ + + G TPL A ++ +A LL+ +
Sbjct: 149 A---AHYDNQKVALL---LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADAN 202
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ G +V A +++ +L+ + A + +KS T L +A D + E+L
Sbjct: 203 AVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVL 260
Score = 44.8 bits (101), Expect = 5e-04
Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 91 IVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
+V LL ++A+ NL + S +TP+ A A D + ++ L+++ ++ + G T
Sbjct: 223 MVSLLLGRNANVNLSNKSGLTPLHLA-----AQEDRV-NVAEVLVNQGAHVDAQTKMGYT 276
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL G + + LL + + ++G+T + A I+ +L++ A E+
Sbjct: 277 PLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNEL 336
Query: 210 DKSNRTLLEIANCHDHQVIIEILK 233
+ T L IA + +++ LK
Sbjct: 337 TVNGNTALGIARRLGYISVVDTLK 360
Score = 36.7 bits (81), Expect = 0.13
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ + K NA K +G+TPL A I+ LL+ +A PN
Sbjct: 285 GNIKIVNFLLQHSAKVNAKTK--NGYTPLHQAAQQGHTHIINVLLQNNASPN 334
>D79994-1|BAA11489.2| 1366|Homo sapiens KIAA0172 protein.
Length = 1366
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 6/194 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A++ + E + + L+ N+ +G T L ++ H+ +IV+ LL+ D H +
Sbjct: 1148 AMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQN 1207
Query: 108 SV--TPIM-AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQ 164
TPIM AA + A+ D IV L + + GQT LM A+S GR+ + +
Sbjct: 1208 KAGYTPIMLAALAAVEAEKDM--RIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVK 1265
Query: 165 KLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI-EKGARLTEVDKSNRTLLEIANCH 223
LL ++ ++D G TA+ A H EI+++L+ + G D T L IA
Sbjct: 1266 GLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEA 1325
Query: 224 DHQVIIEILKKSLN 237
H+ I +L +N
Sbjct: 1326 GHKDIAVLLYAHVN 1339
>BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 61.3 bits (142), Expect = 5e-09
Identities = 51/192 (26%), Positives = 90/192 (46%), Gaps = 9/192 (4%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
D S + + AL A G+ + VE L+ +L N K D+GW+PL A +D
Sbjct: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLL--QLGVPVNDKDDAGWSPLHIAASAGRD 86
Query: 90 KIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+IV+ LL K A N ++ + TP+ A S + + I L++ + D Y
Sbjct: 87 EIVKALLGKGAQVNAVNQNGCTPLHYAASKNR------HEIAVMLLEGGANPDAKDHYEA 140
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T + RA + G + + LL + + ++D G T + A + E ++L+ +G +
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGTSIYI 200
Query: 209 VDKSNRTLLEIA 220
+K +T L++A
Sbjct: 201 ENKEEKTPLQVA 212
Score = 49.2 bits (112), Expect = 2e-05
Identities = 44/149 (29%), Positives = 64/149 (42%), Gaps = 9/149 (6%)
Query: 95 LLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
L +K DS T + ACS + IV L+ +N D G +PL A
Sbjct: 27 LADKSLATRTDQDSRTALHWACSAGHTE------IVEFLLQLGVPVNDKDDAGWSPLHIA 80
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
S+GR + + LL + +Q+G T + +A N+ EI ML+E GA D
Sbjct: 81 ASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA 140
Query: 215 TLLEIANCHDHQVIIEIL---KKSLNLDD 240
T + A + +I IL K S N+ D
Sbjct: 141 TAMHRAAAKGNLKMIHILLYYKASTNIQD 169
>BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 265
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 266 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 379
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 380 CYKGHLDMVRFLLEA-GADQEHKTDE 404
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 432
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 12/156 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 469 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 522
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 523 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
++ ++L++ GA L + + +T+LE + HQV
Sbjct: 580 HTDVADVLLQAGADL-DKQEDMKTILEGIDPAKHQV 614
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 286 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 345
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 346 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 399
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 400 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 459
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 460 RGANLEE 466
>BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein.
Length = 581
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 265
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 266 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 379
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 380 CYKGHLDMVRFLLEA-GADQEHKTDE 404
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 432
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 286 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 345
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 346 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 399
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 400 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 459
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 460 RGANLEE 466
Score = 32.7 bits (71), Expect = 2.1
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 11/96 (11%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 469 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 522
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLL 167
LI + +G TPLM A G + + + LL
Sbjct: 523 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLL 555
>BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 265
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 266 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 379
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 380 CYKGHLDMVRFLLEA-GADQEHKTDE 404
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 432
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 12/156 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 469 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 522
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 523 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
++ ++L++ GA L + + +T+LE + HQV
Sbjct: 580 HTDVADVLLQAGADL-DKQEDMKTILEGIDPAKHQV 614
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 286 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 345
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 346 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 399
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 400 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 459
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 460 RGANLEE 466
>BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein.
Length = 367
Score = 61.3 bits (142), Expect = 5e-09
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E +I L ++ N+ G T L HA +
Sbjct: 96 HSADVNARDKNWQTPLHVAAANKAVKCAEVII--PLLSSVNVSDRGGRTALHHAALNGHV 153
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V LL K A+ N + + +V LI+ + D+ G T
Sbjct: 154 EMVNLLLAKGANINAFDKKDRRALHWAAYMGH-----LDVVALLINHGAEVTCKDKKGYT 208
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A S+G++ V + LL++ V I+ + +G TA+ A ++ Q ++ LI+ GA + +
Sbjct: 209 PLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQP 268
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
+ + T L A H + +E+L
Sbjct: 269 NNNGFTPLHFAAASTHGALCLELL 292
Score = 60.9 bits (141), Expect = 7e-09
Identities = 51/190 (26%), Positives = 93/190 (48%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGW-TPLMHACFHAQDKIVQYLLEKDADPN 103
L +AI +G+ +++ LI+ N LDS TPL A F +I++ L+ A N
Sbjct: 12 LVQAIFSGDPEEIRMLIHKTEDVNT---LDSEKRTPLHVAAFLGDAEIIELLILSGARVN 68
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ +TP+ A ++ S + + LI + +N D+ QTPL A ++ V
Sbjct: 69 AKDNMWLTPLHRAVASRSEEAVQV------LIKHSADVNARDKNWQTPLHVAAANKAVKC 122
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+ ++ + ++ + D+ G TA+ A + E++ +L+ KGA + DK +R L A
Sbjct: 123 AEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAY 182
Query: 223 HDHQVIIEIL 232
H ++ +L
Sbjct: 183 MGHLDVVALL 192
Score = 55.2 bits (127), Expect = 3e-07
Identities = 56/198 (28%), Positives = 89/198 (44%), Gaps = 14/198 (7%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
KK AL A G++ V LIN+ + K G+TPL A + Q +V++LL
Sbjct: 171 KKDRRALHWAAYMGHLDVVALLINHGAEVTCKDK--KGYTPLHAAASNGQINVVKHLLNL 228
Query: 99 DAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
+ ++ T + AC N ++V LID +N + G TPL A +S
Sbjct: 229 GVEIDEINVYGNTALHIACYNGQD------AVVNELIDYGANVNQPNNNGFTPLHFAAAS 282
Query: 158 GRVAVAQKLL---DMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
A+ +LL VNI+ +D G + + H + + LI+ G + VDK
Sbjct: 283 THGALCLELLVNNGADVNIQSKD--GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGN 340
Query: 215 TLLEIANCHDHQVIIEIL 232
T L +A + H+++I L
Sbjct: 341 TPLHVAARYGHELLINTL 358
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/180 (25%), Positives = 87/180 (48%), Gaps = 15/180 (8%)
Query: 30 DYSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHA 87
++ ++++ K KK L A NG + V+ L+N ++ + N+ G T L AC++
Sbjct: 194 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVY---GNTALHIACYNG 250
Query: 88 QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCN--LIDRNCILNIGD 144
QD +V L++ A+ N +++ TP+ A +++ + +C L++ +NI
Sbjct: 251 QDAVVNELIDYGANVNQPNNNGFTPLHFAAAST-------HGALCLELLVNNGADVNIQS 303
Query: 145 RYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA 204
+ G++PL GR +Q L+ I+ D+ G T + A + ++ LI GA
Sbjct: 304 KDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGA 363
Score = 34.7 bits (76), Expect = 0.51
Identities = 25/87 (28%), Positives = 39/87 (44%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
Q PL++AI SG + L+ ++ D T + A EI+E+LI GAR+
Sbjct: 9 QPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVN 68
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILKK 234
D T L A + +++L K
Sbjct: 69 AKDNMWLTPLHRAVASRSEEAVQVLIK 95
>BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein.
Length = 306
Score = 61.3 bits (142), Expect = 5e-09
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E +I L ++ N+ G T L HA +
Sbjct: 35 HSADVNARDKNWQTPLHVAAANKAVKCAEVII--PLLSSVNVSDRGGRTALHHAALNGHV 92
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V LL K A+ N + + +V LI+ + D+ G T
Sbjct: 93 EMVNLLLAKGANINAFDKKDRRALHWAAYMGH-----LDVVALLINHGAEVTCKDKKGYT 147
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A S+G++ V + LL++ V I+ + +G TA+ A ++ Q ++ LI+ GA + +
Sbjct: 148 PLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQP 207
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
+ + T L A H + +E+L
Sbjct: 208 NNNGFTPLHFAAASTHGALCLELL 231
Score = 55.2 bits (127), Expect = 3e-07
Identities = 56/198 (28%), Positives = 89/198 (44%), Gaps = 14/198 (7%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
KK AL A G++ V LIN+ + K G+TPL A + Q +V++LL
Sbjct: 110 KKDRRALHWAAYMGHLDVVALLINHGAEVTCKDK--KGYTPLHAAASNGQINVVKHLLNL 167
Query: 99 DAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
+ ++ T + AC N ++V LID +N + G TPL A +S
Sbjct: 168 GVEIDEINVYGNTALHIACYNGQD------AVVNELIDYGANVNQPNNNGFTPLHFAAAS 221
Query: 158 GRVAVAQKLL---DMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
A+ +LL VNI+ +D G + + H + + LI+ G + VDK
Sbjct: 222 THGALCLELLVNNGADVNIQSKD--GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGN 279
Query: 215 TLLEIANCHDHQVIIEIL 232
T L +A + H+++I L
Sbjct: 280 TPLHVAARYGHELLINTL 297
Score = 49.6 bits (113), Expect = 2e-05
Identities = 28/100 (28%), Positives = 52/100 (52%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
LI + +N D+ QTPL A ++ V A+ ++ + ++ + D+ G TA+ A +
Sbjct: 32 LIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGH 91
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E++ +L+ KGA + DK +R L A H ++ +L
Sbjct: 92 VEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALL 131
Score = 49.6 bits (113), Expect = 2e-05
Identities = 45/180 (25%), Positives = 87/180 (48%), Gaps = 15/180 (8%)
Query: 30 DYSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHA 87
++ ++++ K KK L A NG + V+ L+N ++ + N+ G T L AC++
Sbjct: 133 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVY---GNTALHIACYNG 189
Query: 88 QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCN--LIDRNCILNIGD 144
QD +V L++ A+ N +++ TP+ A +++ + +C L++ +NI
Sbjct: 190 QDAVVNELIDYGANVNQPNNNGFTPLHFAAAST-------HGALCLELLVNNGADVNIQS 242
Query: 145 RYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA 204
+ G++PL GR +Q L+ I+ D+ G T + A + ++ LI GA
Sbjct: 243 KDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGA 302
Score = 39.9 bits (89), Expect = 0.014
Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+N D TPL RA++S Q L+ ++ RD++ T + A + + E++
Sbjct: 6 VNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVI 65
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILKKSLNLDDDHKTDENS 248
I + + D+ RT L A + H +++ +L K N++ K D +
Sbjct: 66 IPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRA 115
>BC038116-1|AAH38116.1| 1194|Homo sapiens ankyrin repeat domain 15
protein.
Length = 1194
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 6/194 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A++ + E + + L+ N+ +G T L ++ H+ +IV+ LL+ D H +
Sbjct: 976 AMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQN 1035
Query: 108 SV--TPIM-AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQ 164
TPIM AA + A+ D IV L + + GQT LM A+S GR+ + +
Sbjct: 1036 KAGYTPIMLAALAAVEAEKDM--RIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVK 1093
Query: 165 KLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI-EKGARLTEVDKSNRTLLEIANCH 223
LL ++ ++D G TA+ A H EI+++L+ + G D T L IA
Sbjct: 1094 GLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEA 1153
Query: 224 DHQVIIEILKKSLN 237
H+ I +L +N
Sbjct: 1154 GHKDIAVLLYAHVN 1167
>BC037495-1|AAH37495.1| 1352|Homo sapiens ANKRD15 protein protein.
Length = 1352
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 6/194 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A++ + E + + L+ N+ +G T L ++ H+ +IV+ LL+ D H +
Sbjct: 1134 AMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQN 1193
Query: 108 SV--TPIM-AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQ 164
TPIM AA + A+ D IV L + + GQT LM A+S GR+ + +
Sbjct: 1194 KAGYTPIMLAALAAVEAEKDM--RIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVK 1251
Query: 165 KLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI-EKGARLTEVDKSNRTLLEIANCH 223
LL ++ ++D G TA+ A H EI+++L+ + G D T L IA
Sbjct: 1252 GLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEA 1311
Query: 224 DHQVIIEILKKSLN 237
H+ I +L +N
Sbjct: 1312 GHKDIAVLLYAHVN 1325
>BC020040-1|AAH20040.1| 784|Homo sapiens ANKRD15 protein protein.
Length = 784
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 6/194 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A++ + E + + L+ N+ +G T L ++ H+ +IV+ LL+ D H +
Sbjct: 566 AMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQN 625
Query: 108 SV--TPIM-AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQ 164
TPIM AA + A+ D IV L + + GQT LM A+S GR+ + +
Sbjct: 626 KAGYTPIMLAALAAVEAEKDM--RIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVK 683
Query: 165 KLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI-EKGARLTEVDKSNRTLLEIANCH 223
LL ++ ++D G TA+ A H EI+++L+ + G D T L IA
Sbjct: 684 GLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEA 743
Query: 224 DHQVIIEILKKSLN 237
H+ I +L +N
Sbjct: 744 GHKDIAVLLYAHVN 757
>BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein.
Length = 579
Score = 61.3 bits (142), Expect = 5e-09
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E +I L ++ N+ G T L HA +
Sbjct: 96 HSADVNARDKNWQTPLHVAAANKAVKCAEVII--PLLSSVNVSDRGGRTALHHAALNGHV 153
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V LL K A+ N + + +V LI+ + D+ G T
Sbjct: 154 EMVNLLLAKGANINAFDKKDRRALHWAAYMGH-----LDVVALLINHGAEVTCKDKKGYT 208
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A S+G++ V + LL++ V I+ + +G TA+ A ++ Q ++ LI+ GA + +
Sbjct: 209 PLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQP 268
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
+ + T L A H + +E+L
Sbjct: 269 NNNGFTPLHFAAASTHGALCLELL 292
Score = 60.9 bits (141), Expect = 7e-09
Identities = 51/190 (26%), Positives = 93/190 (48%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGW-TPLMHACFHAQDKIVQYLLEKDADPN 103
L +AI +G+ +++ LI+ N LDS TPL A F +I++ L+ A N
Sbjct: 12 LVQAIFSGDPEEIRMLIHKTEDVNT---LDSEKRTPLHVAAFLGDAEIIELLILSGARVN 68
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ +TP+ A ++ S + + LI + +N D+ QTPL A ++ V
Sbjct: 69 AKDNMWLTPLHRAVASRSEEAVQV------LIKHSADVNARDKNWQTPLHVAAANKAVKC 122
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+ ++ + ++ + D+ G TA+ A + E++ +L+ KGA + DK +R L A
Sbjct: 123 AEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAY 182
Query: 223 HDHQVIIEIL 232
H ++ +L
Sbjct: 183 MGHLDVVALL 192
Score = 50.4 bits (115), Expect = 1e-05
Identities = 51/220 (23%), Positives = 100/220 (45%), Gaps = 16/220 (7%)
Query: 30 DYSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHA 87
++ ++++ K KK L A NG + V+ L+N ++ + N+ G T L AC++
Sbjct: 194 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVY---GNTALHIACYNG 250
Query: 88 QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCN--LIDRNCILNIGD 144
QD +V L++ A+ N +++ TP+ A +++ + +C L++ +NI
Sbjct: 251 QDAVVNELIDYGANVNQPNNNGFTPLHFAAAST-------HGALCLELLVNNGADVNIQS 303
Query: 145 RYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA 204
+ G++PL GR +Q L+ I+ D+ G T + A + ++ LI GA
Sbjct: 304 KDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGA 363
Query: 205 RLTEVDKSNRTLLEIANCHDH-QVIIEILKKSLNLDDDHK 243
+ + L +A + H ++L +D K
Sbjct: 364 DTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDK 403
Score = 44.8 bits (101), Expect = 5e-04
Identities = 38/151 (25%), Positives = 64/151 (42%), Gaps = 9/151 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADP-NLHSDSVTPIMAACSNSSADNDTIYSIVCN-L 133
G TPL A + + ++ L+ AD S+ P+ A N+ +D C L
Sbjct: 339 GNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSD-------CCRKL 391
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ ++ D++G+T L A + G V + L + +D+ G T + +A +
Sbjct: 392 LSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHF 451
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHD 224
+E L+ GA + E D RT L A D
Sbjct: 452 HCIETLVTTGANVNETDDWGRTALHYAAASD 482
Score = 34.7 bits (76), Expect = 0.51
Identities = 25/87 (28%), Positives = 39/87 (44%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
Q PL++AI SG + L+ ++ D T + A EI+E+LI GAR+
Sbjct: 9 QPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVN 68
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILKK 234
D T L A + +++L K
Sbjct: 69 AKDNMWLTPLHRAVASRSEEAVQVLIK 95
>BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 616
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 197 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 254
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 255 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 308
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 309 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 368
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 369 CYKGHLDMVRFLLEA-GADQEHKTDE 393
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 368 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 421
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 422 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 481
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 482 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 516
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 12/156 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 458 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 511
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 512 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 568
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
++ ++L++ GA L + + +T+LE + HQV
Sbjct: 569 HTDVADVLLQAGADL-DKQEDMKTILEGIDPAKHQV 603
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 275 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 334
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 335 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 388
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 389 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 448
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 449 RGANLEE 455
>BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 265
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 266 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 379
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 380 CYKGHLDMVRFLLEA-GADQEHKTDE 404
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 432
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 12/156 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 469 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 522
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 523 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
++ ++L++ GA L + + +T+LE + HQV
Sbjct: 580 HTDVADVLLQAGADL-DKQEDMKTILEGIDPAKHQV 614
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 286 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 345
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 346 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 399
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 400 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 459
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 460 RGANLEE 466
>AL136979-6|CAH70390.1| 276|Homo sapiens ankyrin repeat domain 15
protein.
Length = 276
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 6/194 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A++ + E + + L+ N+ +G T L ++ H+ +IV+ LL+ D H +
Sbjct: 46 AMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQN 105
Query: 108 SV--TPIM-AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQ 164
TPIM AA + A+ D IV L + + GQT LM A+S GR+ + +
Sbjct: 106 KAGYTPIMLAALAAVEAEKDM--RIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVK 163
Query: 165 KLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI-EKGARLTEVDKSNRTLLEIANCH 223
LL ++ ++D G TA+ A H EI+++L+ + G D T L IA
Sbjct: 164 GLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEA 223
Query: 224 DHQVIIEILKKSLN 237
H+ I +L +N
Sbjct: 224 GHKDIAVLLYAHVN 237
>AL136979-5|CAH70389.1| 330|Homo sapiens ankyrin repeat domain 15
protein.
Length = 330
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 6/194 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A++ + E + + L+ N+ +G T L ++ H+ +IV+ LL+ D H +
Sbjct: 112 AMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQN 171
Query: 108 SV--TPIM-AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQ 164
TPIM AA + A+ D IV L + + GQT LM A+S GR+ + +
Sbjct: 172 KAGYTPIMLAALAAVEAEKDM--RIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVK 229
Query: 165 KLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI-EKGARLTEVDKSNRTLLEIANCH 223
LL ++ ++D G TA+ A H EI+++L+ + G D T L IA
Sbjct: 230 GLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEA 289
Query: 224 DHQVIIEILKKSLN 237
H+ I +L +N
Sbjct: 290 GHKDIAVLLYAHVN 303
>AL136979-4|CAM13084.1| 1194|Homo sapiens ankyrin repeat domain 15
protein.
Length = 1194
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 6/194 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A++ + E + + L+ N+ +G T L ++ H+ +IV+ LL+ D H +
Sbjct: 976 AMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQN 1035
Query: 108 SV--TPIM-AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQ 164
TPIM AA + A+ D IV L + + GQT LM A+S GR+ + +
Sbjct: 1036 KAGYTPIMLAALAAVEAEKDM--RIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVK 1093
Query: 165 KLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI-EKGARLTEVDKSNRTLLEIANCH 223
LL ++ ++D G TA+ A H EI+++L+ + G D T L IA
Sbjct: 1094 GLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEA 1153
Query: 224 DHQVIIEILKKSLN 237
H+ I +L +N
Sbjct: 1154 GHKDIAVLLYAHVN 1167
>AL136979-3|CAH70388.1| 1352|Homo sapiens ankyrin repeat domain 15
protein.
Length = 1352
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/194 (28%), Positives = 91/194 (46%), Gaps = 6/194 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A++ + E + + L+ N+ +G T L ++ H+ +IV+ LL+ D H +
Sbjct: 1134 AMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLDADVCNVDHQN 1193
Query: 108 SV--TPIM-AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQ 164
TPIM AA + A+ D IV L + + GQT LM A+S GR+ + +
Sbjct: 1194 KAGYTPIMLAALAAVEAEKDM--RIVEELFGCGDVNAKASQAGQTALMLAVSHGRIDMVK 1251
Query: 165 KLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI-EKGARLTEVDKSNRTLLEIANCH 223
LL ++ ++D G TA+ A H EI+++L+ + G D T L IA
Sbjct: 1252 GLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEA 1311
Query: 224 DHQVIIEILKKSLN 237
H+ I +L +N
Sbjct: 1312 GHKDIAVLLYAHVN 1325
>AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ45958 fis, clone PLACE7011559, highly similar
to Death-associated protein kinase 1 (EC 2.7.1.-). ).
Length = 337
Score = 61.3 bits (142), Expect = 5e-09
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N NIK G TPL+ A IV+ L E AD N D + A +
Sbjct: 57 NVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQME---- 112
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ L+ + C ++ DR+G TPL A G + + L + N+++ +++G T +
Sbjct: 113 --VIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHL 170
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A ++ +++ L GA + + +T ++A H+ + +L +
Sbjct: 171 AANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLAR 218
Score = 58.4 bits (135), Expect = 4e-08
Identities = 40/156 (25%), Positives = 76/156 (48%), Gaps = 10/156 (6%)
Query: 91 IVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
+ Q L ++PN+ + TP+ A + YS+ L + C +NI +R G+T
Sbjct: 14 VAQLLCSFGSNPNIQDKEEETPLHCAAWHGH------YSVAKALCEAGCNVNIKNREGET 67
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL+ A + G + + L + ++ D+ G A+ AV Q E+++ L+ +G +
Sbjct: 68 PLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQ 127
Query: 210 DKSNRTLLEIANCHDHQ--VIIEILKKSLNLDDDHK 243
D+ T L +A C D +++ + + + NLD +K
Sbjct: 128 DRHGNTPLHVA-CKDGNMPIVVALCEANCNLDISNK 162
Score = 47.6 bits (108), Expect = 7e-05
Identities = 41/155 (26%), Positives = 67/155 (43%), Gaps = 7/155 (4%)
Query: 67 NNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDT 125
+N NI+ TPL A +H + + L E + N+ + + TP++ A + D
Sbjct: 23 SNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKNREGETPLLTASARGYHD--- 79
Query: 126 IYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVF 185
IV L + LN D+ G L A+ ++ V + LL ++ +D+HG T +
Sbjct: 80 ---IVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLH 136
Query: 186 WAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
A I+ L E L +K RT L +A
Sbjct: 137 VACKDGNMPIVVALCEANCNLDISNKYGRTPLHLA 171
>AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein.
Length = 1486
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 222 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 279
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 280 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 333
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 334 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 393
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 394 CYKGHLDMVRFLLEA-GADQEHKTDE 418
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 393 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 446
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 447 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 506
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 507 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 541
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/192 (27%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A G + ++ L+N + N+ G +PLM A + V+ LL+ +D N
Sbjct: 1192 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINA 1251
Query: 104 -LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++ T + AC A+ +V L+DR + + G TPLM A S G V
Sbjct: 1252 QIETNRNTALTLACFQGRAE------VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 1305
Query: 163 AQKLLDM--QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ LLD VN TA+ A + E+LI +GA + +K T L +A
Sbjct: 1306 GRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLA 1365
Query: 221 NCHDHQVIIEIL 232
+ H ++++L
Sbjct: 1366 SNGGHFDVVQLL 1377
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/155 (25%), Positives = 72/155 (46%), Gaps = 12/155 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 483 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 536
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 537 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 593
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQ 226
++ ++L++ GA L + + +T+LE + HQ
Sbjct: 594 HTDVADVLLQAGADL-DKQEDMKTILEGIDPAKHQ 627
Score = 51.6 bits (118), Expect = 4e-06
Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 51 NGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-- 108
+G ++V DL+ N + + S +TPL A I++ LL A+ N + S
Sbjct: 1164 SGGRQEVVDLLLARGANKEHRNV-SDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKL 1222
Query: 109 -VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIG-DRYGQTPLMRAISSGRVAVAQKL 166
++P+M A N V L+D +N + T L A GR V L
Sbjct: 1223 GISPLMLAAMNGHVP------AVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1276
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT--EVDKSNRTLLEIANCHD 224
LD + N+E R + G T + A E+ +L++KGA + V S T L IA
Sbjct: 1277 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG 1336
Query: 225 HQVIIEIL 232
H E+L
Sbjct: 1337 HYKFCELL 1344
Score = 48.0 bits (109), Expect = 5e-05
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 7/135 (5%)
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
D D + S+ T + AC+ + +V LI R+ + D+ G TPL+ A ++G
Sbjct: 1079 DIDAHTESNHDTALTLACAGGHEE------LVSVLIARDAKIEHRDKKGFTPLILAATAG 1132
Query: 159 RVAVAQKLLDMQVNIEMRDQHGW-TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V V + LLD +IE + + T + A + E++++L+ +GA + S+ T L
Sbjct: 1133 HVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPL 1192
Query: 218 EIANCHDHQVIIEIL 232
+A + II+IL
Sbjct: 1193 SLAASGGYVNIIKIL 1207
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 300 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 359
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 360 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 413
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 414 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 473
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 474 RGANLEE 480
Score = 45.2 bits (102), Expect = 4e-04
Identities = 52/210 (24%), Positives = 94/210 (44%), Gaps = 16/210 (7%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
+ AL A G+ + V LI + K K G+TPL+ A +V+ LL+K D
Sbjct: 1089 DTALTLACAGGHEELVSVLIARDAKIEHRDK--KGFTPLILAATAGHVGVVEILLDKGGD 1146
Query: 102 PNLHSDSV--TPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
S+ TP+ ACS + D + + N R N+ D TPL A S G
Sbjct: 1147 IEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHR----NVSD---YTPLSLAASGG 1199
Query: 159 RVAVAQKLLD--MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRT 215
V + + LL+ ++N + G + + A + +++L++ G+ + +++ + T
Sbjct: 1200 YVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNT 1259
Query: 216 LLEIANCHDH-QVIIEILKKSLNLDDDHKT 244
L +A +V+ +L + N++ KT
Sbjct: 1260 ALTLACFQGRAEVVSLLLDRKANVEHRAKT 1289
Score = 43.6 bits (98), Expect = 0.001
Identities = 55/198 (27%), Positives = 82/198 (41%), Gaps = 23/198 (11%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
G +V D + +K A+I+L TPLM A ++V+YLL A N+H+ + T
Sbjct: 529 GGFSEVADFL---IKAGADIELGCS-TPLMEASQEGHLELVKYLLASGA--NVHATTATG 582
Query: 112 IMA---ACSNSSAD-NDTIYSIVCNLI---DRNCILNIGD---------RYGQTPLMRAI 155
A AC N D D + +L D IL D G+TPLM+A
Sbjct: 583 DTALTYACENGHTDVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAA 642
Query: 156 SSGRVAVAQKLLDMQVNIEMRD-QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+G + Q L+ N+ + T V A ++E+L+ GA T K
Sbjct: 643 RAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGS 702
Query: 215 TLLEIANCHDHQVIIEIL 232
T+L A H ++ L
Sbjct: 703 TMLIEAAKGGHTNVVSYL 720
>AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ11979 fis, clone HEMBB1001282, weakly similar to
ANKYRIN R. ).
Length = 435
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 16 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 73
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 74 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 127
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 128 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 187
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 188 CYKGHLDMVRFLLEA-GADQEHKTDE 212
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 187 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 240
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 241 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 300
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 301 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 335
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 12/156 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 277 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 330
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 331 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 387
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
++ ++L++ GA L + + +T+LE + HQV
Sbjct: 388 HTDVADVLLQAGADL-DKQEDMKTILEGIDPAKHQV 422
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 94 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 153
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 154 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 207
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 208 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 267
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 268 RGANLEE 274
>AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 2 protein.
Length = 2617
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 265
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 266 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 379
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 380 CYKGHLDMVRFLLEA-GADQEHKTDE 404
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 432
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/192 (27%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A G + ++ L+N + N+ G +PLM A + V+ LL+ +D N
Sbjct: 1159 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINA 1218
Query: 104 -LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++ T + AC A+ +V L+DR + + G TPLM A S G V
Sbjct: 1219 QIETNRNTALTLACFQGRAE------VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 1272
Query: 163 AQKLLDM--QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ LLD VN TA+ A + E+LI +GA + +K T L +A
Sbjct: 1273 GRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLA 1332
Query: 221 NCHDHQVIIEIL 232
+ H ++++L
Sbjct: 1333 SNGGHFDVVQLL 1344
Score = 54.0 bits (124), Expect = 8e-07
Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 12/169 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 469 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 522
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 523 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIE-ILKKSLNLD 239
++ ++L++ GA L + RT L A H ++ ++ K N++
Sbjct: 580 HTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVN 628
Score = 51.6 bits (118), Expect = 4e-06
Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 51 NGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-- 108
+G ++V DL+ N + + S +TPL A I++ LL A+ N + S
Sbjct: 1131 SGGRQEVVDLLLARGANKEHRNV-SDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKL 1189
Query: 109 -VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIG-DRYGQTPLMRAISSGRVAVAQKL 166
++P+M A N V L+D +N + T L A GR V L
Sbjct: 1190 GISPLMLAAMNGHVP------AVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT--EVDKSNRTLLEIANCHD 224
LD + N+E R + G T + A E+ +L++KGA + V S T L IA
Sbjct: 1244 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG 1303
Query: 225 HQVIIEIL 232
H E+L
Sbjct: 1304 HYKFCELL 1311
Score = 48.0 bits (109), Expect = 5e-05
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 7/135 (5%)
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
D D + S+ T + AC+ + +V LI R+ + D+ G TPL+ A ++G
Sbjct: 1046 DIDAHTESNHDTALTLACAGGHEE------LVSVLIARDAKIEHRDKKGFTPLILAATAG 1099
Query: 159 RVAVAQKLLDMQVNIEMRDQHGW-TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V V + LLD +IE + + T + A + E++++L+ +GA + S+ T L
Sbjct: 1100 HVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPL 1159
Query: 218 EIANCHDHQVIIEIL 232
+A + II+IL
Sbjct: 1160 SLAASGGYVNIIKIL 1174
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 286 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 345
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 346 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 399
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 400 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 459
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 460 RGANLEE 466
Score = 45.2 bits (102), Expect = 4e-04
Identities = 52/210 (24%), Positives = 94/210 (44%), Gaps = 16/210 (7%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
+ AL A G+ + V LI + K K G+TPL+ A +V+ LL+K D
Sbjct: 1056 DTALTLACAGGHEELVSVLIARDAKIEHRDK--KGFTPLILAATAGHVGVVEILLDKGGD 1113
Query: 102 PNLHSDSV--TPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
S+ TP+ ACS + D + + N R N+ D TPL A S G
Sbjct: 1114 IEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHR----NVSD---YTPLSLAASGG 1166
Query: 159 RVAVAQKLLD--MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRT 215
V + + LL+ ++N + G + + A + +++L++ G+ + +++ + T
Sbjct: 1167 YVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNT 1226
Query: 216 LLEIANCHDH-QVIIEILKKSLNLDDDHKT 244
L +A +V+ +L + N++ KT
Sbjct: 1227 ALTLACFQGRAEVVSLLLDRKANVEHRAKT 1256
>AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 1 protein.
Length = 2542
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 265
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 266 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 379
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 380 CYKGHLDMVRFLLEA-GADQEHKTDE 404
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 432
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/192 (27%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A G + ++ L+N + N+ G +PLM A + V+ LL+ +D N
Sbjct: 1159 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINA 1218
Query: 104 -LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++ T + AC A+ +V L+DR + + G TPLM A S G V
Sbjct: 1219 QIETNRNTALTLACFQGRAE------VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 1272
Query: 163 AQKLLDM--QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ LLD VN TA+ A + E+LI +GA + +K T L +A
Sbjct: 1273 GRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLA 1332
Query: 221 NCHDHQVIIEIL 232
+ H ++++L
Sbjct: 1333 SNGGHFDVVQLL 1344
Score = 54.0 bits (124), Expect = 8e-07
Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 12/169 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 469 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 522
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 523 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIE-ILKKSLNLD 239
++ ++L++ GA L + RT L A H ++ ++ K N++
Sbjct: 580 HTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVN 628
Score = 51.6 bits (118), Expect = 4e-06
Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 51 NGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-- 108
+G ++V DL+ N + + S +TPL A I++ LL A+ N + S
Sbjct: 1131 SGGRQEVVDLLLARGANKEHRNV-SDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKL 1189
Query: 109 -VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIG-DRYGQTPLMRAISSGRVAVAQKL 166
++P+M A N V L+D +N + T L A GR V L
Sbjct: 1190 GISPLMLAAMNGHVP------AVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 1243
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT--EVDKSNRTLLEIANCHD 224
LD + N+E R + G T + A E+ +L++KGA + V S T L IA
Sbjct: 1244 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG 1303
Query: 225 HQVIIEIL 232
H E+L
Sbjct: 1304 HYKFCELL 1311
Score = 48.0 bits (109), Expect = 5e-05
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 7/135 (5%)
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
D D + S+ T + AC+ + +V LI R+ + D+ G TPL+ A ++G
Sbjct: 1046 DIDAHTESNHDTALTLACAGGHEE------LVSVLIARDAKIEHRDKKGFTPLILAATAG 1099
Query: 159 RVAVAQKLLDMQVNIEMRDQHGW-TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V V + LLD +IE + + T + A + E++++L+ +GA + S+ T L
Sbjct: 1100 HVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPL 1159
Query: 218 EIANCHDHQVIIEIL 232
+A + II+IL
Sbjct: 1160 SLAASGGYVNIIKIL 1174
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 286 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 345
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 346 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 399
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 400 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 459
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 460 RGANLEE 466
Score = 45.2 bits (102), Expect = 4e-04
Identities = 52/210 (24%), Positives = 94/210 (44%), Gaps = 16/210 (7%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
+ AL A G+ + V LI + K K G+TPL+ A +V+ LL+K D
Sbjct: 1056 DTALTLACAGGHEELVSVLIARDAKIEHRDK--KGFTPLILAATAGHVGVVEILLDKGGD 1113
Query: 102 PNLHSDSV--TPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
S+ TP+ ACS + D + + N R N+ D TPL A S G
Sbjct: 1114 IEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHR----NVSD---YTPLSLAASGG 1166
Query: 159 RVAVAQKLLD--MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRT 215
V + + LL+ ++N + G + + A + +++L++ G+ + +++ + T
Sbjct: 1167 YVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNT 1226
Query: 216 LLEIANCHDH-QVIIEILKKSLNLDDDHKT 244
L +A +V+ +L + N++ KT
Sbjct: 1227 ALTLACFQGRAEVVSLLLDRKANVEHRAKT 1256
>AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein.
Length = 627
Score = 61.3 bits (142), Expect = 5e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 208 SLAEACSDGDVNAVRKLLDEG--RSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 265
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 266 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 379
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 380 CYKGHLDMVRFLLEA-GADQEHKTDE 404
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 432
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 12/156 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 469 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 522
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 523 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
++ ++L++ GA L + + +T+LE + HQV
Sbjct: 580 HTDVADVLLQAGADL-DKQEDMKTILEGIDPAKHQV 614
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 286 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 345
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 346 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 399
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 400 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 459
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 460 RGANLEE 466
>AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein.
Length = 525
Score = 61.3 bits (142), Expect = 5e-09
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 9/204 (4%)
Query: 31 YSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
+S+ ++++ K + L A N +K E +I L ++ N+ G T L HA +
Sbjct: 71 HSADVNARDKNWQTPLHVAAANKAVKCAEVII--PLLSSVNVSDRGGRTALHHAALNGHV 128
Query: 90 KIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQT 149
++V LL K A+ N + + +V LI+ + D+ G T
Sbjct: 129 EMVNLLLAKGANINAFDKKDRRALHWAAYMGH-----LDVVALLINHGAEVTCKDKKGYT 183
Query: 150 PLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEV 209
PL A S+G++ V + LL++ V I+ + +G TA+ A ++ Q ++ LI+ GA + +
Sbjct: 184 PLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQP 243
Query: 210 DKSNRTLLEIANCHDHQVI-IEIL 232
+ + T L A H + +E+L
Sbjct: 244 NNNGFTPLHFAAASTHGALCLELL 267
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/156 (26%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL A F +I++ L+ A N + +TP+ A ++ S + + LI
Sbjct: 18 TPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQV------LIKH 71
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
+ +N D+ QTPL A ++ V A+ ++ + ++ + D+ G TA+ A + E++
Sbjct: 72 SADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMV 131
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+L+ KGA + DK +R L A H ++ +L
Sbjct: 132 NLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALL 167
Score = 50.4 bits (115), Expect = 1e-05
Identities = 51/220 (23%), Positives = 100/220 (45%), Gaps = 16/220 (7%)
Query: 30 DYSSQISSK-KKVEVALQEAIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHA 87
++ ++++ K KK L A NG + V+ L+N ++ + N+ G T L AC++
Sbjct: 169 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVY---GNTALHIACYNG 225
Query: 88 QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCN--LIDRNCILNIGD 144
QD +V L++ A+ N +++ TP+ A +++ + +C L++ +NI
Sbjct: 226 QDAVVNELIDYGANVNQPNNNGFTPLHFAAAST-------HGALCLELLVNNGADVNIQS 278
Query: 145 RYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA 204
+ G++PL GR +Q L+ I+ D+ G T + A + ++ LI GA
Sbjct: 279 KDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGA 338
Query: 205 RLTEVDKSNRTLLEIANCHDH-QVIIEILKKSLNLDDDHK 243
+ + L +A + H ++L +D K
Sbjct: 339 DTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDK 378
Score = 44.8 bits (101), Expect = 5e-04
Identities = 38/151 (25%), Positives = 64/151 (42%), Gaps = 9/151 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADP-NLHSDSVTPIMAACSNSSADNDTIYSIVCN-L 133
G TPL A + + ++ L+ AD S+ P+ A N+ +D C L
Sbjct: 314 GNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSD-------CCRKL 366
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ ++ D++G+T L A + G V + L + +D+ G T + +A +
Sbjct: 367 LSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHF 426
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHD 224
+E L+ GA + E D RT L A D
Sbjct: 427 HCIETLVTTGANVNETDDWGRTALHYAAASD 457
>EF523384-1|ABP57734.1| 1075|Homo sapiens POTE-2 alpha-actin
protein.
Length = 1075
Score = 60.9 bits (141), Expect = 7e-09
Identities = 43/162 (26%), Positives = 76/162 (46%), Gaps = 6/162 (3%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
T L A + ++V+ LL++ N+ + + D + L++
Sbjct: 175 TALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALM-----LLEHG 229
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
NI D YG T L AI + +A+ LL +IE +++HG T + VH + ++++
Sbjct: 230 TDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVK 289
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
LI+K A L +D+ RT L +A C I+ +L + N+D
Sbjct: 290 FLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQ-NID 330
Score = 58.0 bits (134), Expect = 5e-08
Identities = 53/208 (25%), Positives = 96/208 (46%), Gaps = 12/208 (5%)
Query: 26 VRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACF 85
+R+ D + Q K+ AL A NGN + V+ L++ + N+ + T L+ A
Sbjct: 161 LRDTDVNKQDKQKR---TALHLASANGNSEVVKLLLDRRCQ--LNVLDNKKRTALIKAVQ 215
Query: 86 HAQDKIVQYLLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGD 144
+D+ LLE DPN+ + T + A N D + + L + + +
Sbjct: 216 CQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNE----DKLMAKALLLYGAD--IESKN 269
Query: 145 RYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGA 204
++G TPL+ + + V + L+ + N+ D++G TA+ AV I+ +L+E+
Sbjct: 270 KHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNI 329
Query: 205 RLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++ D S +T E A H VI ++L
Sbjct: 330 DVSSQDLSGQTAREYAVSSHHHVICQLL 357
Score = 35.9 bits (79), Expect = 0.22
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVSLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + Q L D
Sbjct: 325 LEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSD 359
>BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 60.9 bits (141), Expect = 7e-09
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 12/206 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDA--D 101
+L EA +G++ V L++ + N + G + L AC ++ Q LL A +
Sbjct: 208 SLAEACSDGDVNAVRKLLDE--CRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVE 265
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVA 161
+ +TP+MAA S D IV L+ + +N G T L A + G V
Sbjct: 266 DRGNKGDITPLMAASSGGYLD------IVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIA 220
+ + LL+ NIE +++G T + A E+ +L++ GA + T ++ + L +A
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLA 379
Query: 221 NCHDHQVIIEILKKSLNLDDDHKTDE 246
H ++ L ++ D +HKTDE
Sbjct: 380 CYKGHLDMVRFLLEA-GADQEHKTDE 404
Score = 57.6 bits (133), Expect = 6e-08
Identities = 38/155 (24%), Positives = 74/155 (47%), Gaps = 8/155 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
AC+ +V++LLE AD +D + T +M AC + + + L+D +N
Sbjct: 379 ACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVE------VARLLLDSGAQVN 432
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ ++PL A G V +A L++ N+E + G+T + A E++ +L+
Sbjct: 433 MPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLA 492
Query: 202 KGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+GA + + +++ T L +A C + + L K+
Sbjct: 493 QGANINAQTEETQETALTLACCGGFSEVADFLIKA 527
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 12/156 (7%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMAACSNSSADNDTIYSIVC 131
D G+TPLM A +++V LL + A+ N ++ T + AC ++ +
Sbjct: 469 DEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSE------VAD 522
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
LI + +G TPLM A G + + + LL N+ G TA+ +A +
Sbjct: 523 FLIKAGADIELG---CSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENG 579
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
++ ++L++ GA L + + +T+LE + HQV
Sbjct: 580 HTDVADVLLQAGADL-DKQEDMKTILEGIDPAKHQV 614
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/187 (22%), Positives = 88/187 (47%), Gaps = 11/187 (5%)
Query: 59 DLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAA 115
D++ L ++A++ S G T L +AC IV+ LL + A+ H+++ TP+M A
Sbjct: 286 DIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEA 345
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
S + + L+D +N + + ++ L A G + + + LL+ + E
Sbjct: 346 ASAGHVEVARV------LLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQE 399
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILK 233
+ TA+ A E+ +L++ GA++ S + L +A C H ++ +++
Sbjct: 400 HKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIE 459
Query: 234 KSLNLDD 240
+ NL++
Sbjct: 460 RGANLEE 466
>AF308292-1|AAG48260.1| 352|Homo sapiens serologically defined
breast cancer antigen NY-BR-49 protein.
Length = 352
Score = 60.9 bits (141), Expect = 7e-09
Identities = 31/100 (31%), Positives = 52/100 (52%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ N N+ +R G TPL A+ V + LL ++++ +D+ WTA+ +A +
Sbjct: 144 LLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGD 203
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+L+EK A + EVD RT + +A H + I+ IL
Sbjct: 204 ESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 243
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/201 (23%), Positives = 88/201 (43%), Gaps = 12/201 (5%)
Query: 5 RPAGFSDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNE 64
R +G S DS G +S + + + L +AI++G+ + ++ +
Sbjct: 57 RLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQ 116
Query: 65 LKNNANIKLDSGWTPLMHACFHA-QDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSAD 122
+ ++ LDSG L+H A Q++ ++LL +A+PNL + TP+ A
Sbjct: 117 ---DVDLALDSG-ASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVER---- 168
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ +V L+ R +N D T L A +G + + LL+ ++ D G T
Sbjct: 169 --RVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT 226
Query: 183 AVFWAVHHNQPEILEMLIEKG 203
+ A H Q I+ +L+ +G
Sbjct: 227 PMHVACQHGQENIVRILLRRG 247
Score = 31.5 bits (68), Expect = 4.8
Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 2/42 (4%)
Query: 65 LKNNANI-KLD-SGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L+ NA++ ++D G TP+ AC H Q+ IV+ LL + D +L
Sbjct: 211 LEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSL 252
>AF269087-1|AAK27325.1| 1341|Homo sapiens breast cancer antigen
NY-BR-1 protein.
Length = 1341
Score = 60.9 bits (141), Expect = 7e-09
Identities = 48/173 (27%), Positives = 82/173 (47%), Gaps = 8/173 (4%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTI 126
N NI+ T L AC + +++V +L+++ + L + TP+M A +
Sbjct: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQ---CHQEAC 65
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
+I LID +N+ D YG L A+ S ++V KLL IE+ ++ T +
Sbjct: 66 ANI---LIDSGADINLVDVYGNMALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLL 122
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
++ +I+E L+ K A V+K T L +A CH I+ +L + N+D
Sbjct: 123 SITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQ-NVD 174
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 86/195 (44%), Gaps = 11/195 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A +NG+ + V L++ K ++ TPLM A Q+ L++ AD N
Sbjct: 20 ALHWACVNGHEEVVTFLVDR--KCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADIN 77
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
L + + A I S+V L+ ++ + ++ TPL+ +I+ +
Sbjct: 78 L-----VDVYGNMALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIV 132
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA-NC 222
+ LL N +++ TA+ AV H EI+ ML+++ + D T A C
Sbjct: 133 EFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTC 192
Query: 223 ---HDHQVIIEILKK 234
H H+ I+E ++K
Sbjct: 193 GFHHIHEQIMEYIRK 207
Score = 35.9 bits (79), Expect = 0.22
Identities = 15/54 (27%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
Query: 171 VNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-LLEIANCH 223
+N+ ++D TA+ WA + E++ L+++ +L +D +RT L++ CH
Sbjct: 8 INLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCH 61
>AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 60.5 bits (140), Expect = 9e-09
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A +G + V L+ + + A K D TPL + + IVQ LL++ A
Sbjct: 467 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGAS 524
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
PN + S TP+ + D + L+D L+I + G TPL A G++
Sbjct: 525 PNAATTSGYTPLHLSAREGHED------VAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 578
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA LL + + + G T + A H++ ++ +L+++GA K+ T L IA
Sbjct: 579 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 638
Score = 56.8 bits (131), Expect = 1e-07
Identities = 49/187 (26%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 48 AIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
A G++ V L+++ N N++ G T L A Q ++V+YL++ A +
Sbjct: 440 AAFMGHVNIVSQLMHHGASPNTTNVR---GETALHMAARSGQAEVVRYLVQDGAQVEAKA 496
Query: 107 -DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQK 165
D TP+ + AD IV L+ + N G TPL + G VA
Sbjct: 497 KDDQTPLHISARLGKAD------IVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD ++ + + G+T + A + + E+ +L++K A KS T L +A +D+
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDN 610
Query: 226 QVIIEIL 232
Q + +L
Sbjct: 611 QKVALLL 617
Score = 51.2 bits (117), Expect = 6e-06
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 10/158 (6%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
+G+TPL A Q I LLE AD N +VT A + +A + +V L+
Sbjct: 630 NGYTPLHIAAKKNQMDIATTLLEYGADAN----AVTRQGIASVHLAAQEGHV-DMVSLLL 684
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
RN N+ G TPL A RV VA+ L++ +++ + + G+T + H+ +
Sbjct: 685 GRNA--NVS---GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 739
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
I+ L++ A++ K+ T L A H II +L
Sbjct: 740 IVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 777
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/199 (23%), Positives = 88/199 (44%), Gaps = 16/199 (8%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ + V L+ N+ K + P +H D K LL+ D + +
Sbjct: 177 LAVALQQGHDQVVSLLLENDTKGKVRL-------PALHIAARKDDTKAAALLLQNDNNAD 229
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ S S TP+ A + + T+ L++R ++ R TPL A G +
Sbjct: 230 VESKSGFTPLHIAAHYGNINVATL------LLNRAAAVDFTARNDITPLHVASKRGNANM 283
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LLD I+ + + G T + +++EML+++ A + K+ + L +A
Sbjct: 284 VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQ 343
Query: 223 HDHQVIIE-ILKKSLNLDD 240
DH ++ +L+ ++ +DD
Sbjct: 344 GDHLNCVQLLLQHNVPVDD 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/104 (24%), Positives = 51/104 (49%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ R ++ + G T L A +G+ V + L+ N+ + Q+G+T ++ A
Sbjct: 89 VVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAA 148
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
N E+++ L++ GA + + T L +A H ++ +L
Sbjct: 149 QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 192
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/190 (26%), Positives = 88/190 (46%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A GN V+ L++ K +A K G TPL +++V+ LL++ A P L
Sbjct: 272 LHVASKRGNANMVKLLLDRGAKIDA--KTRDGLTPLHCGARSGHEQVVEMLLDRAA-PIL 328
Query: 105 HS--DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++P+ A + D+ + V L+ N ++ T L A G V
Sbjct: 329 SKTKNGLSPLHMA---TQGDH---LNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKV 382
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+ LLD + N + +G+T + A N+ +++E+L++ GA + V +S T + +A
Sbjct: 383 AKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAF 442
Query: 223 HDHQVIIEIL 232
H I+ L
Sbjct: 443 MGHVNIVSQL 452
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/177 (22%), Positives = 73/177 (41%), Gaps = 9/177 (5%)
Query: 59 DLINNELKNNA--NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAA 115
D++ L+ A N SG+TPL + + + +LL+ A ++ + TP+ A
Sbjct: 513 DIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVA 572
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + L+ ++ + + G TPL A VA LLD +
Sbjct: 573 AKYGKLEVANL------LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHA 626
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++G+T + A NQ +I L+E GA V + + +A H ++ +L
Sbjct: 627 AAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Score = 44.0 bits (99), Expect = 8e-04
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 14/178 (7%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMA 114
ED+ L + A++ + + G+TPL A + + ++ LL+K A P+ S +TP+
Sbjct: 545 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 604
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
A + DN + + L+D+ + + G TPL A ++ +A LL+ +
Sbjct: 605 A---AHYDNQKVALL---LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADAN 658
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ G +V A +++ +L+ + A + S T L +A D + E+L
Sbjct: 659 AVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQEDRVNVAEVL 711
Score = 43.6 bits (98), Expect = 0.001
Identities = 25/93 (26%), Positives = 47/93 (50%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+NI ++ G L A G V V +LL + N++ + G TA+ A Q E++++L
Sbjct: 67 INICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVL 126
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ GA + ++ T L +A +H +++ L
Sbjct: 127 VTNGANVNAQSQNGFTPLYMAAQENHLEVVKFL 159
Score = 39.5 bits (88), Expect = 0.018
Identities = 21/101 (20%), Positives = 45/101 (44%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+++ ++ + G TPL G + + LL + + ++G+T + A
Sbjct: 711 LVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGH 770
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
I+ +L++ A E+ + T L IA + +++ LK
Sbjct: 771 THIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 811
Score = 36.7 bits (81), Expect = 0.13
Identities = 44/178 (24%), Positives = 73/178 (41%), Gaps = 13/178 (7%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A G+++ V +L+ E +A K G T L A Q ++V+ L+ A+ N
Sbjct: 77 ALHLASKEGHVEVVSELLQREANVDAATK--KGNTALHIASLAGQAEVVKVLVTNGANVN 134
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
S + TP+ A + + +V L+D ++ G TPL A+ G V
Sbjct: 135 AQSQNGFTPLYMAAQENHLE------VVKFLLDNGASQSLATEDGFTPLAVALQQGHDQV 188
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
LL+ ++R A+ A + + +L++ KS T L IA
Sbjct: 189 VSLLLENDTKGKVR----LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIA 242
Score = 36.7 bits (81), Expect = 0.13
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ + K NA K +G+TPL A I+ LL+ +A PN
Sbjct: 736 GNIKIVNFLLQHSAKVNAKTK--NGYTPLHQAAQQGHTHIINVLLQNNASPN 785
Score = 35.9 bits (79), Expect = 0.22
Identities = 36/183 (19%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Query: 23 EKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMH 82
EK ++ S K + A G+++ D I N + + NI +G L
Sbjct: 23 EKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGV--DINICNQNGLNALHL 80
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI 142
A ++V LL+++A+ + + + S + +V L+ +N
Sbjct: 81 ASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAE-----VVKVLVTNGANVNA 135
Query: 143 GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEK 202
+ G TPL A + V + LLD + + + G+T + A+ +++ +L+E
Sbjct: 136 QSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN 195
Query: 203 GAR 205
+
Sbjct: 196 DTK 198
Score = 35.5 bits (78), Expect = 0.29
Identities = 50/207 (24%), Positives = 87/207 (42%), Gaps = 12/207 (5%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
D ++ + SK L A GN+ L+N + + D TPL A
Sbjct: 225 DNNADVESKSGF-TPLHIAAHYGNINVATLLLNRAAAVDFTARNDI--TPLHVASKRGNA 281
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+V+ LL++ A + + D +TP+ C S +V L+DR + + G
Sbjct: 282 NMVKLLLDRGAKIDAKTRDGLTPLH--CGARSGHEQ----VVEMLLDRAAPILSKTKNGL 335
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
+PL A + Q LL V ++ TA+ A H ++ ++L++K A
Sbjct: 336 SPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNA 395
Query: 209 VDKSNRTLLEIANCHDHQV-IIEILKK 234
+ T L IA C +++ ++E+L K
Sbjct: 396 KALNGFTPLHIA-CKKNRIKVMELLLK 421
Score = 34.7 bits (76), Expect = 0.51
Identities = 19/81 (23%), Positives = 39/81 (48%)
Query: 152 MRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+RA +G + A + V+I + +Q+G A+ A E++ L+++ A + K
Sbjct: 46 LRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATK 105
Query: 212 SNRTLLEIANCHDHQVIIEIL 232
T L IA+ ++++L
Sbjct: 106 KGNTALHIASLAGQAEVVKVL 126
Score = 34.3 bits (75), Expect = 0.68
Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 5/149 (3%)
Query: 72 KLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVC 131
K +G +PL A VQ LL+ N+ D VT + +A Y +
Sbjct: 330 KTKNGLSPLHMATQGDHLNCVQLLLQH----NVPVDDVTNDYLTALHVAAHCGH-YKVAK 384
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
L+D+ N G TPL A R+ V + LL +I+ + G T + A
Sbjct: 385 VLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMG 444
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIA 220
I+ L+ GA + T L +A
Sbjct: 445 HVNIVSQLMHHGASPNTTNVRGETALHMA 473
>AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 60.5 bits (140), Expect = 9e-09
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A +G + V L+ + + A K D TPL + + IVQ LL++ A
Sbjct: 82 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGAS 139
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
PN + S TP+ + D + L+D L+I + G TPL A G++
Sbjct: 140 PNAATTSGYTPLHLSAREGHED------VAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 193
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA LL + + + G T + A H++ ++ +L+++GA K+ T L IA
Sbjct: 194 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 253
Score = 56.8 bits (131), Expect = 1e-07
Identities = 49/187 (26%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 48 AIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
A G++ V L+++ N N++ G T L A Q ++V+YL++ A +
Sbjct: 55 AAFMGHVNIVSQLMHHGASPNTTNVR---GETALHMAARSGQAEVVRYLVQDGAQVEAKA 111
Query: 107 -DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQK 165
D TP+ + AD IV L+ + N G TPL + G VA
Sbjct: 112 KDDQTPLHISARLGKAD------IVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 165
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD ++ + + G+T + A + + E+ +L++K A KS T L +A +D+
Sbjct: 166 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDN 225
Query: 226 QVIIEIL 232
Q + +L
Sbjct: 226 QKVALLL 232
Score = 51.2 bits (117), Expect = 6e-06
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 10/158 (6%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
+G+TPL A Q I LLE AD N +VT A + +A + +V L+
Sbjct: 245 NGYTPLHIAAKKNQMDIATTLLEYGADAN----AVTRQGIASVHLAAQEGHV-DMVSLLL 299
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
RN N+ G TPL A RV VA+ L++ +++ + + G+T + H+ +
Sbjct: 300 GRNA--NVS---GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 354
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
I+ L++ A++ K+ T L A H II +L
Sbjct: 355 IVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 392
Score = 50.4 bits (115), Expect = 1e-05
Identities = 42/168 (25%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 66 KNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADND 124
K N N K +G+TPL AC + K+++ LL+ A ++S +TPI A
Sbjct: 5 KANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHV--- 61
Query: 125 TIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAV 184
+IV L+ N + G+T L A SG+ V + L+ +E + + T +
Sbjct: 62 ---NIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPL 118
Query: 185 FWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ + +I++ L+++GA S T L ++ H+ + L
Sbjct: 119 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 166
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/177 (22%), Positives = 73/177 (41%), Gaps = 9/177 (5%)
Query: 59 DLINNELKNNA--NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAA 115
D++ L+ A N SG+TPL + + + +LL+ A ++ + TP+ A
Sbjct: 128 DIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVA 187
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + L+ ++ + + G TPL A VA LLD +
Sbjct: 188 AKYGKLEVANL------LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHA 241
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++G+T + A NQ +I L+E GA V + + +A H ++ +L
Sbjct: 242 AAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 298
Score = 44.0 bits (99), Expect = 8e-04
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 14/178 (7%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMA 114
ED+ L + A++ + + G+TPL A + + ++ LL+K A P+ S +TP+
Sbjct: 160 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 219
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
A + DN + + L+D+ + + G TPL A ++ +A LL+ +
Sbjct: 220 A---AHYDNQKVALL---LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADAN 273
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ G +V A +++ +L+ + A + S T L +A D + E+L
Sbjct: 274 AVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQEDRVNVAEVL 326
Score = 39.5 bits (88), Expect = 0.018
Identities = 21/101 (20%), Positives = 45/101 (44%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+++ ++ + G TPL G + + LL + + ++G+T + A
Sbjct: 326 LVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGH 385
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
I+ +L++ A E+ + T L IA + +++ LK
Sbjct: 386 THIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 426
Score = 36.7 bits (81), Expect = 0.13
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ + K NA K +G+TPL A I+ LL+ +A PN
Sbjct: 351 GNIKIVNFLLQHSAKVNAKTK--NGYTPLHQAAQQGHTHIINVLLQNNASPN 400
Score = 35.1 bits (77), Expect = 0.39
Identities = 19/67 (28%), Positives = 36/67 (53%)
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD + N + +G+T + A N+ +++E+L++ GA + V +S T + +A H
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 226 QVIIEIL 232
I+ L
Sbjct: 61 VNIVSQL 67
Score = 31.9 bits (69), Expect = 3.6
Identities = 23/88 (26%), Positives = 35/88 (39%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+D+ N G TPL A R+ V + LL +I+ + G T + A
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIA 220
I+ L+ GA + T L +A
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMA 88
>AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 60.5 bits (140), Expect = 9e-09
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A +G + V L+ + + A K D TPL + + IVQ LL++ A
Sbjct: 467 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGAS 524
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
PN + S TP+ + D + L+D L+I + G TPL A G++
Sbjct: 525 PNAATTSGYTPLHLSAREGHED------VAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 578
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA LL + + + G T + A H++ ++ +L+++GA K+ T L IA
Sbjct: 579 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 638
Score = 56.8 bits (131), Expect = 1e-07
Identities = 49/187 (26%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 48 AIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
A G++ V L+++ N N++ G T L A Q ++V+YL++ A +
Sbjct: 440 AAFMGHVNIVSQLMHHGASPNTTNVR---GETALHMAARSGQAEVVRYLVQDGAQVEAKA 496
Query: 107 -DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQK 165
D TP+ + AD IV L+ + N G TPL + G VA
Sbjct: 497 KDDQTPLHISARLGKAD------IVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD ++ + + G+T + A + + E+ +L++K A KS T L +A +D+
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDN 610
Query: 226 QVIIEIL 232
Q + +L
Sbjct: 611 QKVALLL 617
Score = 51.2 bits (117), Expect = 6e-06
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 10/158 (6%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
+G+TPL A Q I LLE AD N +VT A + +A + +V L+
Sbjct: 630 NGYTPLHIAAKKNQMDIATTLLEYGADAN----AVTRQGIASVHLAAQEGHV-DMVSLLL 684
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
RN N+ G TPL A RV VA+ L++ +++ + + G+T + H+ +
Sbjct: 685 GRNA--NVS---GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 739
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
I+ L++ A++ K+ T L A H II +L
Sbjct: 740 IVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 777
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/199 (23%), Positives = 88/199 (44%), Gaps = 16/199 (8%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ + V L+ N+ K + P +H D K LL+ D + +
Sbjct: 177 LAVALQQGHDQVVSLLLENDTKGKVRL-------PALHIAARKDDTKAAALLLQNDNNAD 229
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ S S TP+ A + + T+ L++R ++ R TPL A G +
Sbjct: 230 VESKSGFTPLHIAAHYGNINVATL------LLNRAAAVDFTARNDITPLHVASKRGNANM 283
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LLD I+ + + G T + +++EML+++ A + K+ + L +A
Sbjct: 284 VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQ 343
Query: 223 HDHQVIIE-ILKKSLNLDD 240
DH ++ +L+ ++ +DD
Sbjct: 344 GDHLNCVQLLLQHNVPVDD 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/104 (24%), Positives = 51/104 (49%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ R ++ + G T L A +G+ V + L+ N+ + Q+G+T ++ A
Sbjct: 89 VVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAA 148
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
N E+++ L++ GA + + T L +A H ++ +L
Sbjct: 149 QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 192
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/190 (26%), Positives = 88/190 (46%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A GN V+ L++ K +A K G TPL +++V+ LL++ A P L
Sbjct: 272 LHVASKRGNANMVKLLLDRGAKIDA--KTRDGLTPLHCGARSGHEQVVEMLLDRAA-PIL 328
Query: 105 HS--DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++P+ A + D+ + V L+ N ++ T L A G V
Sbjct: 329 SKTKNGLSPLHMA---TQGDH---LNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKV 382
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+ LLD + N + +G+T + A N+ +++E+L++ GA + V +S T + +A
Sbjct: 383 AKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAF 442
Query: 223 HDHQVIIEIL 232
H I+ L
Sbjct: 443 MGHVNIVSQL 452
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/177 (22%), Positives = 73/177 (41%), Gaps = 9/177 (5%)
Query: 59 DLINNELKNNA--NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAA 115
D++ L+ A N SG+TPL + + + +LL+ A ++ + TP+ A
Sbjct: 513 DIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVA 572
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + L+ ++ + + G TPL A VA LLD +
Sbjct: 573 AKYGKLEVANL------LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHA 626
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++G+T + A NQ +I L+E GA V + + +A H ++ +L
Sbjct: 627 AAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Score = 44.0 bits (99), Expect = 8e-04
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 14/178 (7%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMA 114
ED+ L + A++ + + G+TPL A + + ++ LL+K A P+ S +TP+
Sbjct: 545 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 604
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
A + DN + + L+D+ + + G TPL A ++ +A LL+ +
Sbjct: 605 A---AHYDNQKVALL---LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADAN 658
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ G +V A +++ +L+ + A + S T L +A D + E+L
Sbjct: 659 AVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQEDRVNVAEVL 711
Score = 43.6 bits (98), Expect = 0.001
Identities = 25/93 (26%), Positives = 47/93 (50%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+NI ++ G L A G V V +LL + N++ + G TA+ A Q E++++L
Sbjct: 67 INICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVL 126
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ GA + ++ T L +A +H +++ L
Sbjct: 127 VTNGANVNAQSQNGFTPLYMAAQENHLEVVKFL 159
Score = 39.5 bits (88), Expect = 0.018
Identities = 21/101 (20%), Positives = 45/101 (44%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+++ ++ + G TPL G + + LL + + ++G+T + A
Sbjct: 711 LVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGH 770
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
I+ +L++ A E+ + T L IA + +++ LK
Sbjct: 771 THIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 811
Score = 36.7 bits (81), Expect = 0.13
Identities = 44/178 (24%), Positives = 73/178 (41%), Gaps = 13/178 (7%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A G+++ V +L+ E +A K G T L A Q ++V+ L+ A+ N
Sbjct: 77 ALHLASKEGHVEVVSELLQREANVDAATK--KGNTALHIASLAGQAEVVKVLVTNGANVN 134
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
S + TP+ A + + +V L+D ++ G TPL A+ G V
Sbjct: 135 AQSQNGFTPLYMAAQENHLE------VVKFLLDNGASQSLATEDGFTPLAVALQQGHDQV 188
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
LL+ ++R A+ A + + +L++ KS T L IA
Sbjct: 189 VSLLLENDTKGKVR----LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIA 242
Score = 36.7 bits (81), Expect = 0.13
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ + K NA K +G+TPL A I+ LL+ +A PN
Sbjct: 736 GNIKIVNFLLQHSAKVNAKTK--NGYTPLHQAAQQGHTHIINVLLQNNASPN 785
Score = 35.9 bits (79), Expect = 0.22
Identities = 36/183 (19%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Query: 23 EKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMH 82
EK ++ S K + A G+++ D I N + + NI +G L
Sbjct: 23 EKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGV--DINICNQNGLNALHL 80
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI 142
A ++V LL+++A+ + + + S + +V L+ +N
Sbjct: 81 ASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAE-----VVKVLVTNGANVNA 135
Query: 143 GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEK 202
+ G TPL A + V + LLD + + + G+T + A+ +++ +L+E
Sbjct: 136 QSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN 195
Query: 203 GAR 205
+
Sbjct: 196 DTK 198
Score = 35.5 bits (78), Expect = 0.29
Identities = 50/207 (24%), Positives = 87/207 (42%), Gaps = 12/207 (5%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
D ++ + SK L A GN+ L+N + + D TPL A
Sbjct: 225 DNNADVESKSGF-TPLHIAAHYGNINVATLLLNRAAAVDFTARNDI--TPLHVASKRGNA 281
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+V+ LL++ A + + D +TP+ C S +V L+DR + + G
Sbjct: 282 NMVKLLLDRGAKIDAKTRDGLTPLH--CGARSGHEQ----VVEMLLDRAAPILSKTKNGL 335
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
+PL A + Q LL V ++ TA+ A H ++ ++L++K A
Sbjct: 336 SPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNA 395
Query: 209 VDKSNRTLLEIANCHDHQV-IIEILKK 234
+ T L IA C +++ ++E+L K
Sbjct: 396 KALNGFTPLHIA-CKKNRIKVMELLLK 421
Score = 34.7 bits (76), Expect = 0.51
Identities = 19/81 (23%), Positives = 39/81 (48%)
Query: 152 MRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+RA +G + A + V+I + +Q+G A+ A E++ L+++ A + K
Sbjct: 46 LRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATK 105
Query: 212 SNRTLLEIANCHDHQVIIEIL 232
T L IA+ ++++L
Sbjct: 106 KGNTALHIASLAGQAEVVKVL 126
Score = 34.3 bits (75), Expect = 0.68
Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 5/149 (3%)
Query: 72 KLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVC 131
K +G +PL A VQ LL+ N+ D VT + +A Y +
Sbjct: 330 KTKNGLSPLHMATQGDHLNCVQLLLQH----NVPVDDVTNDYLTALHVAAHCGH-YKVAK 384
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
L+D+ N G TPL A R+ V + LL +I+ + G T + A
Sbjct: 385 VLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMG 444
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIA 220
I+ L+ GA + T L +A
Sbjct: 445 HVNIVSQLMHHGASPNTTNVRGETALHMA 473
>AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 60.5 bits (140), Expect = 9e-09
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A +G + V L+ + + A K D TPL + + IVQ LL++ A
Sbjct: 82 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGAS 139
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
PN + S TP+ + D + L+D L+I + G TPL A G++
Sbjct: 140 PNAATTSGYTPLHLSAREGHED------VAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 193
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA LL + + + G T + A H++ ++ +L+++GA K+ T L IA
Sbjct: 194 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 253
Score = 56.8 bits (131), Expect = 1e-07
Identities = 49/187 (26%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 48 AIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
A G++ V L+++ N N++ G T L A Q ++V+YL++ A +
Sbjct: 55 AAFMGHVNIVSQLMHHGASPNTTNVR---GETALHMAARSGQAEVVRYLVQDGAQVEAKA 111
Query: 107 -DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQK 165
D TP+ + AD IV L+ + N G TPL + G VA
Sbjct: 112 KDDQTPLHISARLGKAD------IVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 165
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD ++ + + G+T + A + + E+ +L++K A KS T L +A +D+
Sbjct: 166 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDN 225
Query: 226 QVIIEIL 232
Q + +L
Sbjct: 226 QKVALLL 232
Score = 51.2 bits (117), Expect = 6e-06
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 10/158 (6%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
+G+TPL A Q I LLE AD N +VT A + +A + +V L+
Sbjct: 245 NGYTPLHIAAKKNQMDIATTLLEYGADAN----AVTRQGIASVHLAAQEGHV-DMVSLLL 299
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
RN N+ G TPL A RV VA+ L++ +++ + + G+T + H+ +
Sbjct: 300 GRNA--NVS---GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 354
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
I+ L++ A++ K+ T L A H II +L
Sbjct: 355 IVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 392
Score = 50.4 bits (115), Expect = 1e-05
Identities = 42/168 (25%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 66 KNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADND 124
K N N K +G+TPL AC + K+++ LL+ A ++S +TPI A
Sbjct: 5 KANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHV--- 61
Query: 125 TIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAV 184
+IV L+ N + G+T L A SG+ V + L+ +E + + T +
Sbjct: 62 ---NIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPL 118
Query: 185 FWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ + +I++ L+++GA S T L ++ H+ + L
Sbjct: 119 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 166
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/177 (22%), Positives = 73/177 (41%), Gaps = 9/177 (5%)
Query: 59 DLINNELKNNA--NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAA 115
D++ L+ A N SG+TPL + + + +LL+ A ++ + TP+ A
Sbjct: 128 DIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVA 187
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + L+ ++ + + G TPL A VA LLD +
Sbjct: 188 AKYGKLEVANL------LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHA 241
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++G+T + A NQ +I L+E GA V + + +A H ++ +L
Sbjct: 242 AAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 298
Score = 44.0 bits (99), Expect = 8e-04
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 14/178 (7%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMA 114
ED+ L + A++ + + G+TPL A + + ++ LL+K A P+ S +TP+
Sbjct: 160 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 219
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
A + DN + + L+D+ + + G TPL A ++ +A LL+ +
Sbjct: 220 A---AHYDNQKVALL---LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADAN 273
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ G +V A +++ +L+ + A + S T L +A D + E+L
Sbjct: 274 AVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQEDRVNVAEVL 326
Score = 39.5 bits (88), Expect = 0.018
Identities = 21/101 (20%), Positives = 45/101 (44%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+++ ++ + G TPL G + + LL + + ++G+T + A
Sbjct: 326 LVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGH 385
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
I+ +L++ A E+ + T L IA + +++ LK
Sbjct: 386 THIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 426
Score = 36.7 bits (81), Expect = 0.13
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ + K NA K +G+TPL A I+ LL+ +A PN
Sbjct: 351 GNIKIVNFLLQHSAKVNAKTK--NGYTPLHQAAQQGHTHIINVLLQNNASPN 400
Score = 35.1 bits (77), Expect = 0.39
Identities = 19/67 (28%), Positives = 36/67 (53%)
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD + N + +G+T + A N+ +++E+L++ GA + V +S T + +A H
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 226 QVIIEIL 232
I+ L
Sbjct: 61 VNIVSQL 67
Score = 31.9 bits (69), Expect = 3.6
Identities = 23/88 (26%), Positives = 35/88 (39%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+D+ N G TPL A R+ V + LL +I+ + G T + A
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIA 220
I+ L+ GA + T L +A
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMA 88
>AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 60.5 bits (140), Expect = 9e-09
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A +G + V L+ + + A K D TPL + + IVQ LL++ A
Sbjct: 467 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ--TPLHISARLGKADIVQQLLQQGAS 524
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
PN + S TP+ + D + L+D L+I + G TPL A G++
Sbjct: 525 PNAATTSGYTPLHLSAREGHED------VAAFLLDHGASLSITTKKGFTPLHVAAKYGKL 578
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA LL + + + G T + A H++ ++ +L+++GA K+ T L IA
Sbjct: 579 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 638
Score = 56.8 bits (131), Expect = 1e-07
Identities = 49/187 (26%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Query: 48 AIINGNMKDVEDLINNELK-NNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
A G++ V L+++ N N++ G T L A Q ++V+YL++ A +
Sbjct: 440 AAFMGHVNIVSQLMHHGASPNTTNVR---GETALHMAARSGQAEVVRYLVQDGAQVEAKA 496
Query: 107 -DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQK 165
D TP+ + AD IV L+ + N G TPL + G VA
Sbjct: 497 KDDQTPLHISARLGKAD------IVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550
Query: 166 LLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH 225
LLD ++ + + G+T + A + + E+ +L++K A KS T L +A +D+
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDN 610
Query: 226 QVIIEIL 232
Q + +L
Sbjct: 611 QKVALLL 617
Score = 51.2 bits (117), Expect = 6e-06
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 10/158 (6%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
+G+TPL A Q I LLE AD N +VT A + +A + +V L+
Sbjct: 630 NGYTPLHIAAKKNQMDIATTLLEYGADAN----AVTRQGIASVHLAAQEGHV-DMVSLLL 684
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
RN N+ G TPL A RV VA+ L++ +++ + + G+T + H+ +
Sbjct: 685 GRNA--NVS---GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIK 739
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
I+ L++ A++ K+ T L A H II +L
Sbjct: 740 IVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 777
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/199 (23%), Positives = 88/199 (44%), Gaps = 16/199 (8%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ + V L+ N+ K + P +H D K LL+ D + +
Sbjct: 177 LAVALQQGHDQVVSLLLENDTKGKVRL-------PALHIAARKDDTKAAALLLQNDNNAD 229
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ S S TP+ A + + T+ L++R ++ R TPL A G +
Sbjct: 230 VESKSGFTPLHIAAHYGNINVATL------LLNRAAAVDFTARNDITPLHVASKRGNANM 283
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LLD I+ + + G T + +++EML+++ A + K+ + L +A
Sbjct: 284 VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQ 343
Query: 223 HDHQVIIE-ILKKSLNLDD 240
DH ++ +L+ ++ +DD
Sbjct: 344 GDHLNCVQLLLQHNVPVDD 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/104 (24%), Positives = 51/104 (49%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ R ++ + G T L A +G+ V + L+ N+ + Q+G+T ++ A
Sbjct: 89 VVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAA 148
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
N E+++ L++ GA + + T L +A H ++ +L
Sbjct: 149 QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 192
Score = 46.0 bits (104), Expect = 2e-04
Identities = 50/190 (26%), Positives = 88/190 (46%), Gaps = 11/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A GN V+ L++ K +A K G TPL +++V+ LL++ A P L
Sbjct: 272 LHVASKRGNANMVKLLLDRGAKIDA--KTRDGLTPLHCGARSGHEQVVEMLLDRAA-PIL 328
Query: 105 HS--DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++P+ A + D+ + V L+ N ++ T L A G V
Sbjct: 329 SKTKNGLSPLHMA---TQGDH---LNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKV 382
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
A+ LLD + N + +G+T + A N+ +++E+L++ GA + V +S T + +A
Sbjct: 383 AKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAF 442
Query: 223 HDHQVIIEIL 232
H I+ L
Sbjct: 443 MGHVNIVSQL 452
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/177 (22%), Positives = 73/177 (41%), Gaps = 9/177 (5%)
Query: 59 DLINNELKNNA--NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAA 115
D++ L+ A N SG+TPL + + + +LL+ A ++ + TP+ A
Sbjct: 513 DIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVA 572
Query: 116 CSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + L+ ++ + + G TPL A VA LLD +
Sbjct: 573 AKYGKLEVANL------LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHA 626
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++G+T + A NQ +I L+E GA V + + +A H ++ +L
Sbjct: 627 AAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Score = 44.0 bits (99), Expect = 8e-04
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 14/178 (7%)
Query: 58 EDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMA 114
ED+ L + A++ + + G+TPL A + + ++ LL+K A P+ S +TP+
Sbjct: 545 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 604
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
A + DN + + L+D+ + + G TPL A ++ +A LL+ +
Sbjct: 605 A---AHYDNQKVALL---LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADAN 658
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ G +V A +++ +L+ + A + S T L +A D + E+L
Sbjct: 659 AVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHLAAQEDRVNVAEVL 711
Score = 43.6 bits (98), Expect = 0.001
Identities = 25/93 (26%), Positives = 47/93 (50%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+NI ++ G L A G V V +LL + N++ + G TA+ A Q E++++L
Sbjct: 67 INICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVL 126
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ GA + ++ T L +A +H +++ L
Sbjct: 127 VTNGANVNAQSQNGFTPLYMAAQENHLEVVKFL 159
Score = 39.5 bits (88), Expect = 0.018
Identities = 21/101 (20%), Positives = 45/101 (44%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+++ ++ + G TPL G + + LL + + ++G+T + A
Sbjct: 711 LVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGH 770
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
I+ +L++ A E+ + T L IA + +++ LK
Sbjct: 771 THIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 811
Score = 36.7 bits (81), Expect = 0.13
Identities = 44/178 (24%), Positives = 73/178 (41%), Gaps = 13/178 (7%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A G+++ V +L+ E +A K G T L A Q ++V+ L+ A+ N
Sbjct: 77 ALHLASKEGHVEVVSELLQREANVDAATK--KGNTALHIASLAGQAEVVKVLVTNGANVN 134
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
S + TP+ A + + +V L+D ++ G TPL A+ G V
Sbjct: 135 AQSQNGFTPLYMAAQENHLE------VVKFLLDNGASQSLATEDGFTPLAVALQQGHDQV 188
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
LL+ ++R A+ A + + +L++ KS T L IA
Sbjct: 189 VSLLLENDTKGKVR----LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIA 242
Score = 36.7 bits (81), Expect = 0.13
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ + K NA K +G+TPL A I+ LL+ +A PN
Sbjct: 736 GNIKIVNFLLQHSAKVNAKTK--NGYTPLHQAAQQGHTHIINVLLQNNASPN 785
Score = 35.9 bits (79), Expect = 0.22
Identities = 36/183 (19%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Query: 23 EKPVRNYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMH 82
EK ++ S K + A G+++ D I N + + NI +G L
Sbjct: 23 EKKRKHRKRSRDRKKKSDANASYLRAARAGHLEKALDYIKNGV--DINICNQNGLNALHL 80
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI 142
A ++V LL+++A+ + + + S + +V L+ +N
Sbjct: 81 ASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAE-----VVKVLVTNGANVNA 135
Query: 143 GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEK 202
+ G TPL A + V + LLD + + + G+T + A+ +++ +L+E
Sbjct: 136 QSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN 195
Query: 203 GAR 205
+
Sbjct: 196 DTK 198
Score = 35.5 bits (78), Expect = 0.29
Identities = 50/207 (24%), Positives = 87/207 (42%), Gaps = 12/207 (5%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD 89
D ++ + SK L A GN+ L+N + + D TPL A
Sbjct: 225 DNNADVESKSGF-TPLHIAAHYGNINVATLLLNRAAAVDFTARNDI--TPLHVASKRGNA 281
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+V+ LL++ A + + D +TP+ C S +V L+DR + + G
Sbjct: 282 NMVKLLLDRGAKIDAKTRDGLTPLH--CGARSGHEQ----VVEMLLDRAAPILSKTKNGL 335
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
+PL A + Q LL V ++ TA+ A H ++ ++L++K A
Sbjct: 336 SPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNA 395
Query: 209 VDKSNRTLLEIANCHDHQV-IIEILKK 234
+ T L IA C +++ ++E+L K
Sbjct: 396 KALNGFTPLHIA-CKKNRIKVMELLLK 421
Score = 34.7 bits (76), Expect = 0.51
Identities = 19/81 (23%), Positives = 39/81 (48%)
Query: 152 MRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+RA +G + A + V+I + +Q+G A+ A E++ L+++ A + K
Sbjct: 46 LRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATK 105
Query: 212 SNRTLLEIANCHDHQVIIEIL 232
T L IA+ ++++L
Sbjct: 106 KGNTALHIASLAGQAEVVKVL 126
Score = 34.3 bits (75), Expect = 0.68
Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 5/149 (3%)
Query: 72 KLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVC 131
K +G +PL A VQ LL+ N+ D VT + +A Y +
Sbjct: 330 KTKNGLSPLHMATQGDHLNCVQLLLQH----NVPVDDVTNDYLTALHVAAHCGH-YKVAK 384
Query: 132 NLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHN 191
L+D+ N G TPL A R+ V + LL +I+ + G T + A
Sbjct: 385 VLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMG 444
Query: 192 QPEILEMLIEKGARLTEVDKSNRTLLEIA 220
I+ L+ GA + T L +A
Sbjct: 445 HVNIVSQLMHHGASPNTTNVRGETALHMA 473
>AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kinase
domain containing 1 protein.
Length = 765
Score = 60.5 bits (140), Expect = 9e-09
Identities = 48/161 (29%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLI 134
GWTPL A + + + + L+ + ADPNLH ++ TP+ A S+V L
Sbjct: 461 GWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHV------SLVKLLT 514
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+ L+ R +TPL A+ G+V Q LL + DQ G+ + A +
Sbjct: 515 SQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYL 574
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
I +ML+ GA L T L +A H II +L +S
Sbjct: 575 ICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAES 615
Score = 58.4 bits (135), Expect = 4e-08
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Query: 65 LKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSA 121
L+ A+++L + GWTPL A + +I+ L E A+ L + + TP+ A +
Sbjct: 580 LRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEE 639
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
++V L+ N ++ G TPL A+ LL+ N+ R++ GW
Sbjct: 640 ------AVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGW 693
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
T A IL++L+E GA+L D + T L++A Q I+ L+
Sbjct: 694 TPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLE 745
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/218 (23%), Positives = 99/218 (45%), Gaps = 15/218 (6%)
Query: 10 SDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEV------ALQEAIINGNMKDVEDLINN 63
S E DSD + ++ ++ D + + +++ + L + G+++ V L+ +
Sbjct: 325 SQELMDSDSGNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAH 384
Query: 64 ELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSAD 122
E+ + + + SG+TPL+ A Q + LL AD N + D P+ A N D
Sbjct: 385 EV--DVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNG--D 440
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ T L+D ++ +R G TPL A + VA+ L+ Q + + + G T
Sbjct: 441 DGTARL----LLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKT 496
Query: 183 AVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ A + ++++L +GA L ++ RT L +A
Sbjct: 497 PLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLA 534
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/181 (22%), Positives = 79/181 (43%), Gaps = 8/181 (4%)
Query: 53 NMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TP 111
N ++V L+ + + + N+ G TPL A + +V+ L + A+ + ++ TP
Sbjct: 472 NFENVARLLVSR-QADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTP 530
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ A + +L+ + + D+ G PL A + G+ + + LL
Sbjct: 531 LHLAVERGKV------RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGA 584
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
++E+ GWT + A + EI+ +L E A + + N T L +A H + ++
Sbjct: 585 SLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSA 644
Query: 232 L 232
L
Sbjct: 645 L 645
Score = 46.4 bits (105), Expect = 2e-04
Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL + V+ LL + D + + S TP++ A + D + L+
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPD------LCALLLAH 417
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N D G PL A +G A+ LLD ++ +++ GWT + A +N +
Sbjct: 418 GADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVA 477
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+L+ + A + +T L +A H ++++L
Sbjct: 478 RLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLL 513
Score = 44.0 bits (99), Expect = 8e-04
Identities = 35/144 (24%), Positives = 58/144 (40%), Gaps = 7/144 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL A + + +Q+LL+ A P+ L P+ A + Y I L+
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGK------YLICKMLLRY 582
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
L + G TPL A G + + L + N+ WT + A H + ++
Sbjct: 583 GASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVV 642
Query: 197 EMLIEKGARLTEVDKSNRTLLEIA 220
L++ GA ++S T L +A
Sbjct: 643 SALLQCGADPNAAEQSGWTPLHLA 666
>AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein.
Length = 765
Score = 60.5 bits (140), Expect = 9e-09
Identities = 48/161 (29%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLI 134
GWTPL A + + + + L+ + ADPNLH ++ TP+ A S+V L
Sbjct: 461 GWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHV------SLVKLLT 514
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+ L+ R +TPL A+ G+V Q LL + DQ G+ + A +
Sbjct: 515 SQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYL 574
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
I +ML+ GA L T L +A H II +L +S
Sbjct: 575 ICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAES 615
Score = 58.4 bits (135), Expect = 4e-08
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Query: 65 LKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSA 121
L+ A+++L + GWTPL A + +I+ L E A+ L + + TP+ A +
Sbjct: 580 LRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEE 639
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
++V L+ N ++ G TPL A+ LL+ N+ R++ GW
Sbjct: 640 ------AVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGW 693
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
T A IL++L+E GA+L D + T L++A Q I+ L+
Sbjct: 694 TPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLE 745
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/218 (23%), Positives = 99/218 (45%), Gaps = 15/218 (6%)
Query: 10 SDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEV------ALQEAIINGNMKDVEDLINN 63
S E DSD + ++ ++ D + + +++ + L + G+++ V L+ +
Sbjct: 325 SQELMDSDSGNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAH 384
Query: 64 ELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSAD 122
E+ + + + SG+TPL+ A Q + LL AD N + D P+ A N D
Sbjct: 385 EV--DVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNG--D 440
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ T L+D ++ +R G TPL A + VA+ L+ Q + + + G T
Sbjct: 441 DGTARL----LLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKT 496
Query: 183 AVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ A + ++++L +GA L ++ RT L +A
Sbjct: 497 PLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLA 534
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/181 (22%), Positives = 79/181 (43%), Gaps = 8/181 (4%)
Query: 53 NMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TP 111
N ++V L+ + + + N+ G TPL A + +V+ L + A+ + ++ TP
Sbjct: 472 NFENVARLLVSR-QADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTP 530
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ A + +L+ + + D+ G PL A + G+ + + LL
Sbjct: 531 LHLAVERGKV------RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGA 584
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
++E+ GWT + A + EI+ +L E A + + N T L +A H + ++
Sbjct: 585 SLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSA 644
Query: 232 L 232
L
Sbjct: 645 L 645
Score = 46.4 bits (105), Expect = 2e-04
Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL + V+ LL + D + + S TP++ A + D + L+
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPD------LCALLLAH 417
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N D G PL A +G A+ LLD ++ +++ GWT + A +N +
Sbjct: 418 GADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVA 477
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+L+ + A + +T L +A H ++++L
Sbjct: 478 RLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLL 513
Score = 44.0 bits (99), Expect = 8e-04
Identities = 35/144 (24%), Positives = 58/144 (40%), Gaps = 7/144 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL A + + +Q+LL+ A P+ L P+ A + Y I L+
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGK------YLICKMLLRY 582
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
L + G TPL A G + + L + N+ WT + A H + ++
Sbjct: 583 GASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVV 642
Query: 197 EMLIEKGARLTEVDKSNRTLLEIA 220
L++ GA ++S T L +A
Sbjct: 643 SALLQCGADPNAAEQSGWTPLHLA 666
>AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2
protein.
Length = 765
Score = 60.5 bits (140), Expect = 9e-09
Identities = 48/161 (29%), Positives = 72/161 (44%), Gaps = 7/161 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLI 134
GWTPL A + + + + L+ + ADPNLH ++ TP+ A S+V L
Sbjct: 461 GWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHV------SLVKLLT 514
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+ L+ R +TPL A+ G+V Q LL + DQ G+ + A +
Sbjct: 515 SQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYL 574
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
I +ML+ GA L T L +A H II +L +S
Sbjct: 575 ICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAES 615
Score = 58.4 bits (135), Expect = 4e-08
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 9/172 (5%)
Query: 65 LKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSA 121
L+ A+++L + GWTPL A + +I+ L E A+ L + + TP+ A +
Sbjct: 580 LRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEE 639
Query: 122 DNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGW 181
++V L+ N ++ G TPL A+ LL+ N+ R++ GW
Sbjct: 640 ------AVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGW 693
Query: 182 TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
T A IL++L+E GA+L D + T L++A Q I+ L+
Sbjct: 694 TPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLE 745
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/218 (23%), Positives = 99/218 (45%), Gaps = 15/218 (6%)
Query: 10 SDEDSDSDDYGFYEKPVRNYDYSSQISSKKKVEV------ALQEAIINGNMKDVEDLINN 63
S E DSD + ++ ++ D + + +++ + L + G+++ V L+ +
Sbjct: 325 SQELMDSDSGNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAH 384
Query: 64 ELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSAD 122
E+ + + + SG+TPL+ A Q + LL AD N + D P+ A N D
Sbjct: 385 EV--DVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNG--D 440
Query: 123 NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
+ T L+D ++ +R G TPL A + VA+ L+ Q + + + G T
Sbjct: 441 DGTARL----LLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKT 496
Query: 183 AVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ A + ++++L +GA L ++ RT L +A
Sbjct: 497 PLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLA 534
Score = 52.0 bits (119), Expect = 3e-06
Identities = 40/181 (22%), Positives = 79/181 (43%), Gaps = 8/181 (4%)
Query: 53 NMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TP 111
N ++V L+ + + + N+ G TPL A + +V+ L + A+ + ++ TP
Sbjct: 472 NFENVARLLVSR-QADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTP 530
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ A + +L+ + + D+ G PL A + G+ + + LL
Sbjct: 531 LHLAVERGKV------RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGA 584
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
++E+ GWT + A + EI+ +L E A + + N T L +A H + ++
Sbjct: 585 SLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSA 644
Query: 232 L 232
L
Sbjct: 645 L 645
Score = 46.4 bits (105), Expect = 2e-04
Identities = 36/156 (23%), Positives = 66/156 (42%), Gaps = 7/156 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL + V+ LL + D + + S TP++ A + D + L+
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPD------LCALLLAH 417
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
N D G PL A +G A+ LLD ++ +++ GWT + A +N +
Sbjct: 418 GADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVA 477
Query: 197 EMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+L+ + A + +T L +A H ++++L
Sbjct: 478 RLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLL 513
Score = 44.0 bits (99), Expect = 8e-04
Identities = 35/144 (24%), Positives = 58/144 (40%), Gaps = 7/144 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL A + + +Q+LL+ A P+ L P+ A + Y I L+
Sbjct: 529 TPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGK------YLICKMLLRY 582
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
L + G TPL A G + + L + N+ WT + A H + ++
Sbjct: 583 GASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVV 642
Query: 197 EMLIEKGARLTEVDKSNRTLLEIA 220
L++ GA ++S T L +A
Sbjct: 643 SALLQCGADPNAAEQSGWTPLHLA 666
>AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 518
Score = 60.1 bits (139), Expect = 1e-08
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 10/208 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ EA + +++ ++ LIN + N +K G+ L A KIVQ LLE ADPN
Sbjct: 47 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILN-IGDRYGQTPLMRAISSGRVA 161
+ + TP+ A N D ++ L+ +N G L +A
Sbjct: 107 ATTLEETTPLFLAVENGQID------VLRLLLQHGANVNGSHSMCGWNSLHQASFQDNAE 160
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL N E +D G T +F A + + E L +LI GA + T L IA
Sbjct: 161 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAA 220
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSY 249
H +E+L S D D +E+S+
Sbjct: 221 QEGHTKCVELLLSS-GADPDLYCNEDSW 247
Score = 54.0 bits (124), Expect = 8e-07
Identities = 41/170 (24%), Positives = 74/170 (43%), Gaps = 5/170 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
GN+K + L+ + ++ + GW P+ A +H + +Q L+ D+ N +
Sbjct: 21 GNVKVLRKLLKKG--RSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENY--IKMKT 76
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
C+ A + + IV L++ N TPL A+ +G++ V + LL
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGA 136
Query: 172 NIE-MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
N+ GW ++ A + EI+++L+ KGA D T L +A
Sbjct: 137 NVNGSHSMCGWNSLHQASFQDNAEIIKLLLRKGANKECQDDFGITPLFVA 186
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-- 211
A G V V +KLL ++++ D GW + A +HN E L+MLI + +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 212 -SNRTLLEIANCHDHQVIIEIL 232
L +A H I++IL
Sbjct: 77 FEGFCALHLAASQGHWKIVQIL 98
>AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens
cDNA FLJ34236 fis, clone FCBBF3027199, weakly similar to
ANKYRIN. ).
Length = 505
Score = 60.1 bits (139), Expect = 1e-08
Identities = 42/153 (27%), Positives = 72/153 (47%), Gaps = 5/153 (3%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
SG++P+ A + + ++ LLE L + TP+ A N+ D+ ++ +
Sbjct: 219 SGYSPMHWASYTGHEDCLELLLEHSPFSYLEGNPFTPLHCAVINNQ---DSTTEMLLGAL 275
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
I+N D G+TPL A + V+ + LL Q + D G TA+ A + Q
Sbjct: 276 GAK-IVNSRDTKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTA 334
Query: 195 ILEMLIEKG-ARLTEVDKSNRTLLEIANCHDHQ 226
+E L+ +G A LT +D++ T L +A H+
Sbjct: 335 AVEFLLYRGKADLTVLDENKNTALHLACSKGHE 367
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/209 (25%), Positives = 93/209 (44%), Gaps = 9/209 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A NG+ + ++ L E N +++ G T L A + V+ L A +
Sbjct: 18 LHLAAYNGHCEALKTLA--ETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALI 75
Query: 105 --HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
TP+ AA + S D+++ ++ + +R I ++ D YGQTPLM AI +G V
Sbjct: 76 KERKRKWTPLHAAAA--SGHTDSLHLLI-DSGERADITDVMDVYGQTPLMLAIMNGHVDC 132
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
LL+ + D G TA+ + L L++ A + D RT + +A+
Sbjct: 133 VHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASA 192
Query: 223 HDHQVIIE-ILKKSLNLDD-DHKTDENSY 249
H ++ +L+ +L+ D D D + Y
Sbjct: 193 CGHTAVLRTLLQAALSTDPLDAGVDYSGY 221
Score = 42.7 bits (96), Expect = 0.002
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
NC+ ++ +PL A +G + L + VN+++RD G TA+F A E +
Sbjct: 4 NCLEDVESTIPVSPLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECV 63
Query: 197 EMLIEKGA-RLTEVDKSNRTLLEIANCHDHQVIIEIL 232
E+L GA L + K T L A H + +L
Sbjct: 64 EVLTAHGASALIKERKRKWTPLHAAAASGHTDSLHLL 100
Score = 41.5 bits (93), Expect = 0.004
Identities = 40/175 (22%), Positives = 77/175 (44%), Gaps = 10/175 (5%)
Query: 32 SSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDS-GWTPLMHACFHAQDK 90
S+ I +K+ L A +G+ + LI++ + + +D G TPLM A +
Sbjct: 72 SALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDVYGQTPLMLAIMNGHVD 131
Query: 91 IVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTP 150
V LLEK + + + + + ++ + L+D + + D G+TP
Sbjct: 132 CVHLLLEKGSTADAADLRGRTALHRGAVTGCED-----CLAALLDHDAFVLCRDFKGRTP 186
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMRDQ----HGWTAVFWAVHHNQPEILEMLIE 201
+ A + G AV + LL ++ + D G++ + WA + + LE+L+E
Sbjct: 187 IHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLE 241
>BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein.
Length = 553
Score = 59.7 bits (138), Expect = 2e-08
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 10/208 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ EA + +++ ++ LIN + N +K G+ L A KIVQ LLE ADPN
Sbjct: 82 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 141
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILN-IGDRYGQTPLMRAISSGRVA 161
+ + TP+ A N D ++ L+ +N G L +A
Sbjct: 142 ATTLEETTPLFLAVENGQID------VLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 195
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL N E +D G T +F A + + E L +LI GA + T L IA
Sbjct: 196 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAA 255
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSY 249
H +E+L S D D +E+S+
Sbjct: 256 QEGHTKCVELLLSS-GADPDLYCNEDSW 282
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
GN+K + L+ + ++ + GW P+ A +H + +Q L+ D+ N +
Sbjct: 56 GNVKVLRKLLKKG--RSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENY--IKMKT 111
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
C+ A + + IV L++ N TPL A+ +G++ V + LL
Sbjct: 112 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGA 171
Query: 172 NIE-MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
N+ GW ++ A EI+++L+ KGA D T L +A
Sbjct: 172 NVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVA 221
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-- 211
A G V V +KLL ++++ D GW + A +HN E L+MLI + +
Sbjct: 52 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 111
Query: 212 -SNRTLLEIANCHDHQVIIEIL 232
L +A H I++IL
Sbjct: 112 FEGFCALHLAASQGHWKIVQIL 133
>BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 35
protein.
Length = 1001
Score = 59.7 bits (138), Expect = 2e-08
Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 9/169 (5%)
Query: 55 KDVEDLINNELKNNANI--KLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTP 111
K + + + L N A+I K + G T L A Q + V+ LL+ A+ + + +++ +P
Sbjct: 64 KGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSP 123
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ A S+ A S V L D L++ D G+TPLM A G A+ +LL
Sbjct: 124 LHWAASSGCA------SSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGA 177
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ + D++ +A+ A E+ E+L+ GA VD + L A
Sbjct: 178 RVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 40.3 bits (90), Expect = 0.010
Identities = 25/77 (32%), Positives = 38/77 (49%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D GQ+P A S G LL +I +++ G TA+ A QP+ +++L++ G
Sbjct: 51 DSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHG 110
Query: 204 ARLTEVDKSNRTLLEIA 220
A VD NR+ L A
Sbjct: 111 ANEDAVDAENRSPLHWA 127
Score = 33.9 bits (74), Expect = 0.89
Identities = 37/155 (23%), Positives = 63/155 (40%), Gaps = 8/155 (5%)
Query: 98 KDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAIS 156
K A P L S+ +P A S + TI L+ +N + G T L A
Sbjct: 43 KSARPTKLDSNGQSPFHLAASKGLTECLTI------LLANGADINSKNEDGSTALHLATI 96
Query: 157 SGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTL 216
S + + LL N + D + + WA + +L + A L +D RT
Sbjct: 97 SCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTP 156
Query: 217 LEIANCHDHQVII-EILKKSLNLDDDHKTDENSYL 250
L IA+ H I ++L++ ++ K D+++ +
Sbjct: 157 LMIASLGGHAAICSQLLQRGARVNVTDKNDKSALI 191
>BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 35
protein.
Length = 1001
Score = 59.7 bits (138), Expect = 2e-08
Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 9/169 (5%)
Query: 55 KDVEDLINNELKNNANI--KLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTP 111
K + + + L N A+I K + G T L A Q + V+ LL+ A+ + + +++ +P
Sbjct: 64 KGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSP 123
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ A S+ A S V L D L++ D G+TPLM A G A+ +LL
Sbjct: 124 LHWAASSGCA------SSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGA 177
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ + D++ +A+ A E+ E+L+ GA VD + L A
Sbjct: 178 RVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 40.3 bits (90), Expect = 0.010
Identities = 25/77 (32%), Positives = 38/77 (49%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D GQ+P A S G LL +I +++ G TA+ A QP+ +++L++ G
Sbjct: 51 DSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHG 110
Query: 204 ARLTEVDKSNRTLLEIA 220
A VD NR+ L A
Sbjct: 111 ANEDAVDAENRSPLHWA 127
Score = 33.9 bits (74), Expect = 0.89
Identities = 37/155 (23%), Positives = 63/155 (40%), Gaps = 8/155 (5%)
Query: 98 KDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAIS 156
K A P L S+ +P A S + TI L+ +N + G T L A
Sbjct: 43 KSARPTKLDSNGQSPFHLAASKGLTECLTI------LLANGADINSKNEDGSTALHLATI 96
Query: 157 SGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTL 216
S + + LL N + D + + WA + +L + A L +D RT
Sbjct: 97 SCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTP 156
Query: 217 LEIANCHDHQVII-EILKKSLNLDDDHKTDENSYL 250
L IA+ H I ++L++ ++ K D+++ +
Sbjct: 157 LMIASLGGHAAICSQLLQRGARVNVTDKNDKSALI 191
>BC066981-1|AAH66981.1| 381|Homo sapiens POTE15 protein protein.
Length = 381
Score = 59.7 bits (138), Expect = 2e-08
Identities = 45/162 (27%), Positives = 75/162 (46%), Gaps = 6/162 (3%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
T L A + ++VQ LL++ N+ + + D V L++
Sbjct: 175 TALHLASANGNSEVVQLLLDRRCQLNVLGNKKRTALIKAVQCQEDE-----CVLMLLEHG 229
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
NI D YG T L AI + +A+ LL +IE +++ G T + VH + E+++
Sbjct: 230 ADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVK 289
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
LI+K A L +D+ RT L +A C I+ +L + N+D
Sbjct: 290 FLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQ-NVD 330
Score = 58.4 bits (135), Expect = 4e-08
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ V LLE
Sbjct: 171 KQKRTALHLASANGNSEVVQLLLDRRCQ--LNVLGNKKRTALIKAVQCQEDECVLMLLEH 228
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD N+ + A + + D + + L + + ++ G TPL+ +
Sbjct: 229 GADGNIQDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKCGLTPLLLGVHEQ 283
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 284 KQEVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTARE 343
Query: 219 IANCHDHQVIIEIL 232
A H VI E+L
Sbjct: 344 YAVSSHHHVICELL 357
Score = 37.9 bits (84), Expect = 0.055
Identities = 27/97 (27%), Positives = 47/97 (48%)
Query: 136 RNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
R+ +N D+ +T L A ++G V Q LLD + + + TA+ AV + E
Sbjct: 162 RDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLGNKKRTALIKAVQCQEDEC 221
Query: 196 LEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ ML+E GA D+ T L A ++ +++ + L
Sbjct: 222 VLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKAL 258
Score = 33.9 bits (74), Expect = 0.89
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVNLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + + L D
Sbjct: 325 LEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSD 359
>BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 59.7 bits (138), Expect = 2e-08
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 10/208 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ EA + +++ ++ LIN + N +K G+ L A KIVQ LLE ADPN
Sbjct: 47 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILN-IGDRYGQTPLMRAISSGRVA 161
+ + TP+ A N D ++ L+ +N G L +A
Sbjct: 107 ATTLEETTPLFLAVENGQID------VLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 160
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL N E +D G T +F A + + E L +LI GA + T L IA
Sbjct: 161 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAA 220
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSY 249
H +E+L S D D +E+S+
Sbjct: 221 QEGHTKCVELLLSS-GADPDLYCNEDSW 247
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
GN+K + L+ + ++ + GW P+ A +H + +Q L+ D+ N +
Sbjct: 21 GNVKVLRKLLKKG--RSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENY--IKMKT 76
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
C+ A + + IV L++ N TPL A+ +G++ V + LL
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGA 136
Query: 172 NIE-MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
N+ GW ++ A EI+++L+ KGA D T L +A
Sbjct: 137 NVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVA 186
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-- 211
A G V V +KLL ++++ D GW + A +HN E L+MLI + +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 212 -SNRTLLEIANCHDHQVIIEIL 232
L +A H I++IL
Sbjct: 77 FEGFCALHLAASQGHWKIVQIL 98
>BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 59.7 bits (138), Expect = 2e-08
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 10/208 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ EA + +++ ++ LIN + N +K G+ L A KIVQ LLE ADPN
Sbjct: 47 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILN-IGDRYGQTPLMRAISSGRVA 161
+ + TP+ A N D ++ L+ +N G L +A
Sbjct: 107 ATTLEETTPLFLAVENGQID------VLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 160
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL N E +D G T +F A + + E L +LI GA + T L IA
Sbjct: 161 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAA 220
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSY 249
H +E+L S D D +E+S+
Sbjct: 221 QEGHTKCVELLLSS-GADPDLYCNEDSW 247
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
GN+K + L+ + ++ + GW P+ A +H + +Q L+ D+ N +
Sbjct: 21 GNVKVLRKLLKKG--RSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENY--IKMKT 76
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
C+ A + + IV L++ N TPL A+ +G++ V + LL
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGA 136
Query: 172 NIE-MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
N+ GW ++ A EI+++L+ KGA D T L +A
Sbjct: 137 NVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVA 186
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-- 211
A G V V +KLL ++++ D GW + A +HN E L+MLI + +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 212 -SNRTLLEIANCHDHQVIIEIL 232
L +A H I++IL
Sbjct: 77 FEGFCALHLAASQGHWKIVQIL 98
>AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 512
Score = 59.7 bits (138), Expect = 2e-08
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 10/208 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ EA + +++ ++ LIN + N +K G+ L A KIVQ LLE ADPN
Sbjct: 41 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 100
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILN-IGDRYGQTPLMRAISSGRVA 161
+ + TP+ A N D ++ L+ +N G L +A
Sbjct: 101 ATTLEETTPLFLAVENGQID------VLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 154
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL N E +D G T +F A + + E L +LI GA + T L IA
Sbjct: 155 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAA 214
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSY 249
H +E+L S D D +E+S+
Sbjct: 215 QEGHTKCVELLLSS-GADPDLYCNEDSW 241
Score = 51.6 bits (118), Expect = 4e-06
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 5/169 (2%)
Query: 53 NMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPI 112
N+K + L+ + ++ + GW P+ A +H + +Q L+ D+ N +
Sbjct: 16 NVKVLRQLLKKG--RSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENY--IKMKTF 71
Query: 113 MAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVN 172
C+ A + + IV L++ N TPL A+ +G++ V + LL N
Sbjct: 72 EGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGAN 131
Query: 173 IE-MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ GW ++ A EI+++L+ KGA D T L +A
Sbjct: 132 VNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVA 180
Score = 35.9 bits (79), Expect = 0.22
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 3/82 (3%)
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-- 211
A V V ++LL ++++ D GW + A +HN E L+MLI + +
Sbjct: 11 AAREANVKVLRQLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 70
Query: 212 -SNRTLLEIANCHDHQVIIEIL 232
L +A H I++IL
Sbjct: 71 FEGFCALHLAASQGHWKIVQIL 92
>AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ10123 fis, clone HEMBA1002939, weakly similar to
ANKYRIN R. ).
Length = 518
Score = 59.7 bits (138), Expect = 2e-08
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 10/208 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ EA + +++ ++ LIN + N +K G+ L A KIVQ LLE ADPN
Sbjct: 47 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILN-IGDRYGQTPLMRAISSGRVA 161
+ + TP+ A N D ++ L+ +N G L +A
Sbjct: 107 ATTLEETTPLFLAVENGQID------VLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 160
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL N E +D G T +F A + + E L +LI GA + T L IA
Sbjct: 161 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAA 220
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSY 249
H +E+L S D D +E+S+
Sbjct: 221 QEGHTKCVELLLSS-GADPDLYCNEDSW 247
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
GN+K + L+ + ++ + GW P+ A +H + +Q L+ D+ N +
Sbjct: 21 GNVKVLRKLLKKG--RSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENY--IKMKT 76
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
C+ A + + IV L++ N TPL A+ +G++ V + LL
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGA 136
Query: 172 NIE-MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
N+ GW ++ A EI+++L+ KGA D T L +A
Sbjct: 137 NVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVA 186
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-- 211
A G V V +KLL ++++ D GW + A +HN E L+MLI + +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 212 -SNRTLLEIANCHDHQVIIEIL 232
L +A H I++IL
Sbjct: 77 FEGFCALHLAASQGHWKIVQIL 98
>AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein.
Length = 518
Score = 59.7 bits (138), Expect = 2e-08
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 10/208 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ EA + +++ ++ LIN + N +K G+ L A KIVQ LLE ADPN
Sbjct: 47 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILN-IGDRYGQTPLMRAISSGRVA 161
+ + TP+ A N D ++ L+ +N G L +A
Sbjct: 107 ATTLEETTPLFLAVENGQID------VLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 160
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL N E +D G T +F A + + E L +LI GA + T L IA
Sbjct: 161 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAA 220
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSY 249
H +E+L S D D +E+S+
Sbjct: 221 QEGHTKCVELLLSS-GADPDLYCNEDSW 247
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
GN+K + L+ + ++ + GW P+ A +H + +Q L+ D+ N +
Sbjct: 21 GNVKVLRKLLKKG--RSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENY--IKMKT 76
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
C+ A + + IV L++ N TPL A+ +G++ V + LL
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGA 136
Query: 172 NIE-MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
N+ GW ++ A EI+++L+ KGA D T L +A
Sbjct: 137 NVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVA 186
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-- 211
A G V V +KLL ++++ D GW + A +HN E L+MLI + +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 212 -SNRTLLEIANCHDHQVIIEIL 232
L +A H I++IL
Sbjct: 77 FEGFCALHLAASQGHWKIVQIL 98
>AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein.
Length = 326
Score = 59.7 bits (138), Expect = 2e-08
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 10/208 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ EA + +++ ++ LIN + N +K G+ L A KIVQ LLE ADPN
Sbjct: 47 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 106
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILN-IGDRYGQTPLMRAISSGRVA 161
+ + TP+ A N D ++ L+ +N G L +A
Sbjct: 107 ATTLEETTPLFLAVENGQID------VLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 160
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL N E +D G T +F A + + E L +LI GA + T L IA
Sbjct: 161 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAA 220
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSY 249
H +E+L S D D +E+S+
Sbjct: 221 QEGHTKCVELLLSS-GADPDLYCNEDSW 247
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
GN+K + L+ + ++ + GW P+ A +H + +Q L+ D+ N +
Sbjct: 21 GNVKVLRKLLKKG--RSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENY--IKMKT 76
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
C+ A + + IV L++ N TPL A+ +G++ V + LL
Sbjct: 77 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGA 136
Query: 172 NIE-MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
N+ GW ++ A EI+++L+ KGA D T L +A
Sbjct: 137 NVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVA 186
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-- 211
A G V V +KLL ++++ D GW + A +HN E L+MLI + +
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 212 -SNRTLLEIANCHDHQVIIEIL 232
L +A H I++IL
Sbjct: 77 FEGFCALHLAASQGHWKIVQIL 98
>AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 340
Score = 59.7 bits (138), Expect = 2e-08
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 10/208 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNN-ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+ EA + +++ ++ LIN + N +K G+ L A KIVQ LLE ADPN
Sbjct: 57 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 116
Query: 104 LHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILN-IGDRYGQTPLMRAISSGRVA 161
+ + TP+ A N D ++ L+ +N G L +A
Sbjct: 117 ATTLEETTPLFLAVENGQID------VLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 170
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL N E +D G T +F A + + E L +LI GA + T L IA
Sbjct: 171 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAA 230
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSY 249
H +E+L S D D +E+S+
Sbjct: 231 QEGHTKCVELLLSS-GADPDLYCNEDSW 257
Score = 53.6 bits (123), Expect = 1e-06
Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 5/170 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
GN+K + L+ + ++ + GW P+ A +H + +Q L+ D+ N +
Sbjct: 31 GNVKVLRKLLKKG--RSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENY--IKMKT 86
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
C+ A + + IV L++ N TPL A+ +G++ V + LL
Sbjct: 87 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGA 146
Query: 172 NIE-MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
N+ GW ++ A EI+++L+ KGA D T L +A
Sbjct: 147 NVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVA 196
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK-- 211
A G V V +KLL ++++ D GW + A +HN E L+MLI + +
Sbjct: 27 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 86
Query: 212 -SNRTLLEIANCHDHQVIIEIL 232
L +A H I++IL
Sbjct: 87 FEGFCALHLAASQGHWKIVQIL 108
>BC022878-1|AAH22878.1| 776|Homo sapiens ankyrin repeat domain 5
protein.
Length = 776
Score = 59.3 bits (137), Expect = 2e-08
Identities = 29/81 (35%), Positives = 46/81 (56%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+++ D Y +TPLM A +SG + V + LL+ N+ D WT + +A H Q +I+E+L
Sbjct: 518 VDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELL 577
Query: 200 IEKGARLTEVDKSNRTLLEIA 220
+E GA + +N T L A
Sbjct: 578 VESGALIDAASINNSTPLNRA 598
Score = 56.0 bits (129), Expect = 2e-07
Identities = 38/126 (30%), Positives = 64/126 (50%), Gaps = 7/126 (5%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDR 136
TPLM AC +V++LLEK A+ N + + TP+ AC D IV L++
Sbjct: 527 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQD------IVELLVES 580
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
+++ TPL RAI S R+ + LLD+ ++ ++ G +A+ A + I+
Sbjct: 581 GALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRII 640
Query: 197 EMLIEK 202
+++ EK
Sbjct: 641 DLIKEK 646
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
Query: 157 SGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTL 216
+G +A +K + + ++M+D + T + A ++++ L+EKGA + D T
Sbjct: 502 AGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTP 561
Query: 217 LEIANCH-DHQVIIEILKKSLNLDDDHKTDENSYLNHQLTS 256
L A CH Q I+E+L +S L D + ++ LN + S
Sbjct: 562 LHFA-CHAGQQDIVELLVESGALIDAASINNSTPLNRAIES 601
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A +GN+ V+ L+ E N N + WTPL AC Q IV+ L+E A +
Sbjct: 529 LMTACASGNIDVVKFLL--EKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDA 586
Query: 105 HS-DSVTPIMAACSNSSAD 122
S ++ TP+ A + D
Sbjct: 587 ASINNSTPLNRAIESCRLD 605
Score = 31.1 bits (67), Expect = 6.3
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 5/107 (4%)
Query: 84 CFHAQDKIVQYLLEKDADPNLHSDSVTPI--MAACSNSSADNDTIYSIVCNLIDRNCILN 141
C +DK L K P L + PI ++A +S ND +V L+D +
Sbjct: 19 CVRNKDKKQIEKLTKLGYPEL-INYTEPINGLSALHLASVSNDI--DMVSFLLDLGAHPD 75
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+ DR G TP MRA G + L + ++ + D G +F+ +
Sbjct: 76 VQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCI 122
>AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.
Length = 1710
Score = 59.3 bits (137), Expect = 2e-08
Identities = 56/206 (27%), Positives = 97/206 (47%), Gaps = 19/206 (9%)
Query: 95 LLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
LL K+ + + T + AC+N + +V L+DR C LN+ D +T LM+A
Sbjct: 67 LLRKNGLNDRDKMNRTALHLACANGHPE------VVTLLVDRKCQLNVCDNENRTALMKA 120
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+ A LL+ + + D HG TA+ +AV++ + L+ A + +K +
Sbjct: 121 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL 180
Query: 215 TLLEIANCHDHQVIIE-ILKKSLNLDDDHKTDENSYLNHQLTSWQDYYPGIEKNER-PNY 272
T L +A Q ++E ++KK N++ K + +HQL S +Y K ER P +
Sbjct: 181 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLES----SHQLIS--EY-----KEERIPKH 229
Query: 273 KNEIQNLLYGMSCERLTPLIVTSGID 298
++ N + S + L+ L G+D
Sbjct: 230 SSQNSNSVDESSEDSLSRLSGKPGVD 255
Score = 45.6 bits (103), Expect = 3e-04
Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
Query: 153 RAISSGRVAVAQKLLDMQVN-IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+A S+G VA Q++L ++ N + RD+ TA+ A + PE++ +L+++ +L D
Sbjct: 52 KAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDN 111
Query: 212 SNRT-LLEIANCHDHQVIIEILKKSL--NLDDDH 242
NRT L++ C + + +L+ NL D H
Sbjct: 112 ENRTALMKAVQCQEEKCATILLEHGADPNLADVH 145
Score = 34.7 bits (76), Expect = 0.51
Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K AL A NG+ + V L++ K N+ + T LM A ++K LLE
Sbjct: 78 KMNRTALHLACANGHPEVVTLLVDR--KCQLNVCDNENRTALMKAVQCQEEKCATILLEH 135
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
ADPNL + + + N+ I S+ L+ + + ++ TPL+ A+S
Sbjct: 136 GADPNLADVHGNTAL----HYAVYNEDI-SVATKLLLYDANIEAKNKDDLTPLLLAVSGK 190
Query: 159 RVAVAQKLLDMQVNIEMRDQ 178
+ + + L+ + N+ D+
Sbjct: 191 KQQMVEFLIKKKANVNAVDK 210
>AL109754-1|CAB87618.2| 776|Homo sapiens ankyrin repeat domain 5
protein.
Length = 776
Score = 59.3 bits (137), Expect = 2e-08
Identities = 29/81 (35%), Positives = 46/81 (56%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+++ D Y +TPLM A +SG + V + LL+ N+ D WT + +A H Q +I+E+L
Sbjct: 518 VDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELL 577
Query: 200 IEKGARLTEVDKSNRTLLEIA 220
+E GA + +N T L A
Sbjct: 578 VESGALIDAASINNSTPLNRA 598
Score = 56.0 bits (129), Expect = 2e-07
Identities = 38/126 (30%), Positives = 64/126 (50%), Gaps = 7/126 (5%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDR 136
TPLM AC +V++LLEK A+ N + + TP+ AC D IV L++
Sbjct: 527 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQD------IVELLVES 580
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
+++ TPL RAI S R+ + LLD+ ++ ++ G +A+ A + I+
Sbjct: 581 GALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRII 640
Query: 197 EMLIEK 202
+++ EK
Sbjct: 641 DLIKEK 646
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
Query: 157 SGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTL 216
+G +A +K + + ++M+D + T + A ++++ L+EKGA + D T
Sbjct: 502 AGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTP 561
Query: 217 LEIANCH-DHQVIIEILKKSLNLDDDHKTDENSYLNHQLTS 256
L A CH Q I+E+L +S L D + ++ LN + S
Sbjct: 562 LHFA-CHAGQQDIVELLVESGALIDAASINNSTPLNRAIES 601
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A +GN+ V+ L+ E N N + WTPL AC Q IV+ L+E A +
Sbjct: 529 LMTACASGNIDVVKFLL--EKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDA 586
Query: 105 HS-DSVTPIMAACSNSSAD 122
S ++ TP+ A + D
Sbjct: 587 ASINNSTPLNRAIESCRLD 605
Score = 31.1 bits (67), Expect = 6.3
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 5/107 (4%)
Query: 84 CFHAQDKIVQYLLEKDADPNLHSDSVTPI--MAACSNSSADNDTIYSIVCNLIDRNCILN 141
C +DK L K P L + PI ++A +S ND +V L+D +
Sbjct: 19 CVRNKDKKQIEKLTKLGYPEL-INYTEPINGLSALHLASVSNDI--DMVSFLLDLGAHPD 75
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+ DR G TP MRA G + L + ++ + D G +F+ +
Sbjct: 76 VQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCI 122
>AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens
cDNA FLJ33801 fis, clone CTONG2000411. ).
Length = 1001
Score = 59.3 bits (137), Expect = 2e-08
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Query: 55 KDVEDLINNELKNNANI--KLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTP 111
K + + + L N A+I K + G T L A Q + V+ LL+ A+ + + +++ +P
Sbjct: 64 KGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENRSP 123
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ A S+ A S V L D L++ D G+TPLM A G A+ +LL
Sbjct: 124 LHWAASSGCA------SSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGA 177
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ + D++ A+ A E+ E+L+ GA VD + L A
Sbjct: 178 RVNVTDKNDKAALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYA 226
Score = 40.3 bits (90), Expect = 0.010
Identities = 25/77 (32%), Positives = 38/77 (49%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D GQ+P A S G LL +I +++ G TA+ A QP+ +++L++ G
Sbjct: 51 DSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHG 110
Query: 204 ARLTEVDKSNRTLLEIA 220
A VD NR+ L A
Sbjct: 111 ANEDAVDAENRSPLHWA 127
Score = 32.7 bits (71), Expect = 2.1
Identities = 37/151 (24%), Positives = 60/151 (39%), Gaps = 8/151 (5%)
Query: 98 KDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAIS 156
K A P L S+ +P A S + TI L+ +N + G T L A
Sbjct: 43 KSARPTKLDSNGQSPFHLAASKGLTECLTI------LLANGADINSKNEDGSTALHLATI 96
Query: 157 SGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTL 216
S + + LL N + D + + WA + +L + A L +D RT
Sbjct: 97 SCQPQCVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTP 156
Query: 217 LEIANCHDHQVII-EILKKSLNLDDDHKTDE 246
L IA+ H I ++L++ ++ K D+
Sbjct: 157 LMIASLGGHAAICSQLLQRGARVNVTDKNDK 187
>AK025322-1|BAB15111.1| 416|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21669 fis, clone COL08988. ).
Length = 416
Score = 59.3 bits (137), Expect = 2e-08
Identities = 29/81 (35%), Positives = 46/81 (56%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+++ D Y +TPLM A +SG + V + LL+ N+ D WT + +A H Q +I+E+L
Sbjct: 158 VDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELL 217
Query: 200 IEKGARLTEVDKSNRTLLEIA 220
+E GA + +N T L A
Sbjct: 218 VESGALIDAASINNSTPLNRA 238
Score = 56.0 bits (129), Expect = 2e-07
Identities = 38/126 (30%), Positives = 64/126 (50%), Gaps = 7/126 (5%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDR 136
TPLM AC +V++LLEK A+ N + + TP+ AC D IV L++
Sbjct: 167 TPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQD------IVELLVES 220
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
+++ TPL RAI S R+ + LLD+ ++ ++ G +A+ A + I+
Sbjct: 221 GALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRII 280
Query: 197 EMLIEK 202
+++ EK
Sbjct: 281 DLIKEK 286
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
Query: 157 SGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTL 216
+G +A +K + + ++M+D + T + A ++++ L+EKGA + D T
Sbjct: 142 AGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTP 201
Query: 217 LEIANCH-DHQVIIEILKKSLNLDDDHKTDENSYLNHQLTS 256
L A CH Q I+E+L +S L D + ++ LN + S
Sbjct: 202 LHFA-CHAGQQDIVELLVESGALIDAASINNSTPLNRAIES 241
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A +GN+ V+ L+ E N N + WTPL AC Q IV+ L+E A +
Sbjct: 169 LMTACASGNIDVVKFLL--EKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDA 226
Query: 105 HS-DSVTPIMAACSNSSAD 122
S ++ TP+ A + D
Sbjct: 227 ASINNSTPLNRAIESCRLD 245
>AK001137-1|BAA91516.1| 546|Homo sapiens protein ( Homo sapiens
cDNA FLJ10275 fis, clone HEMBB1001175, weakly similar to
ANKYRIN. ).
Length = 546
Score = 59.3 bits (137), Expect = 2e-08
Identities = 56/206 (27%), Positives = 97/206 (47%), Gaps = 19/206 (9%)
Query: 95 LLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
LL K+ + + T + AC+N + +V L+DR C LN+ D +T LM+A
Sbjct: 67 LLRKNGLNDRDKMNRTALHLACANGHPE------VVTLLVDRKCQLNVCDNENRTALMKA 120
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+ A LL+ + + D HG TA+ +AV++ + L+ A + +K +
Sbjct: 121 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL 180
Query: 215 TLLEIANCHDHQVIIE-ILKKSLNLDDDHKTDENSYLNHQLTSWQDYYPGIEKNER-PNY 272
T L +A Q ++E ++KK N++ K + +HQL S +Y K ER P +
Sbjct: 181 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLES----SHQLIS--EY-----KEERIPKH 229
Query: 273 KNEIQNLLYGMSCERLTPLIVTSGID 298
++ N + S + L+ L G+D
Sbjct: 230 SSQNSNSVDESSEDSLSRLSGKPGVD 255
Score = 45.6 bits (103), Expect = 3e-04
Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
Query: 153 RAISSGRVAVAQKLLDMQVN-IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+A S+G VA Q++L ++ N + RD+ TA+ A + PE++ +L+++ +L D
Sbjct: 52 KAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDN 111
Query: 212 SNRT-LLEIANCHDHQVIIEILKKSL--NLDDDH 242
NRT L++ C + + +L+ NL D H
Sbjct: 112 ENRTALMKAVQCQEEKCATILLEHGADPNLADVH 145
Score = 34.7 bits (76), Expect = 0.51
Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K AL A NG+ + V L++ K N+ + T LM A ++K LLE
Sbjct: 78 KMNRTALHLACANGHPEVVTLLVDR--KCQLNVCDNENRTALMKAVQCQEEKCATILLEH 135
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
ADPNL + + + N+ I S+ L+ + + ++ TPL+ A+S
Sbjct: 136 GADPNLADVHGNTAL----HYAVYNEDI-SVATKLLLYDANIEAKNKDDLTPLLLAVSGK 190
Query: 159 RVAVAQKLLDMQVNIEMRDQ 178
+ + + L+ + N+ D+
Sbjct: 191 KQQMVEFLIKKKANVNAVDK 210
>AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.
Length = 1715
Score = 59.3 bits (137), Expect = 2e-08
Identities = 56/206 (27%), Positives = 97/206 (47%), Gaps = 19/206 (9%)
Query: 95 LLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
LL K+ + + T + AC+N + +V L+DR C LN+ D +T LM+A
Sbjct: 73 LLRKNGLNDRDKMNRTALHLACANGHPE------VVTLLVDRKCQLNVCDNENRTALMKA 126
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+ A LL+ + + D HG TA+ +AV++ + L+ A + +K +
Sbjct: 127 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL 186
Query: 215 TLLEIANCHDHQVIIE-ILKKSLNLDDDHKTDENSYLNHQLTSWQDYYPGIEKNER-PNY 272
T L +A Q ++E ++KK N++ K + +HQL S +Y K ER P +
Sbjct: 187 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLES----SHQLIS--EY-----KEERIPKH 235
Query: 273 KNEIQNLLYGMSCERLTPLIVTSGID 298
++ N + S + L+ L G+D
Sbjct: 236 SSQNSNSVDESSEDSLSRLSGKPGVD 261
Score = 45.6 bits (103), Expect = 3e-04
Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
Query: 153 RAISSGRVAVAQKLLDMQVN-IEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+A S+G VA Q++L ++ N + RD+ TA+ A + PE++ +L+++ +L D
Sbjct: 58 KAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDN 117
Query: 212 SNRT-LLEIANCHDHQVIIEILKKSL--NLDDDH 242
NRT L++ C + + +L+ NL D H
Sbjct: 118 ENRTALMKAVQCQEEKCATILLEHGADPNLADVH 151
Score = 34.7 bits (76), Expect = 0.51
Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K AL A NG+ + V L++ K N+ + T LM A ++K LLE
Sbjct: 84 KMNRTALHLACANGHPEVVTLLVDR--KCQLNVCDNENRTALMKAVQCQEEKCATILLEH 141
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
ADPNL + + + N+ I S+ L+ + + ++ TPL+ A+S
Sbjct: 142 GADPNLADVHGNTAL----HYAVYNEDI-SVATKLLLYDANIEAKNKDDLTPLLLAVSGK 196
Query: 159 RVAVAQKLLDMQVNIEMRDQ 178
+ + + L+ + N+ D+
Sbjct: 197 KQQMVEFLIKKKANVNAVDK 216
>X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein.
Length = 319
Score = 58.8 bits (136), Expect = 3e-08
Identities = 28/80 (35%), Positives = 46/80 (57%)
Query: 141 NIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI 200
++ D Y +T L RA G +A+ +KL++ IE RD TA+ WA ++L++L+
Sbjct: 147 DVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLL 206
Query: 201 EKGARLTEVDKSNRTLLEIA 220
KGA+++ DK T L +A
Sbjct: 207 NKGAKISARDKLLSTALHVA 226
Score = 42.3 bits (95), Expect = 0.003
Identities = 36/173 (20%), Positives = 80/173 (46%), Gaps = 7/173 (4%)
Query: 47 EAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
+A + + VE +++ KNN ++ + T L AC IV+ L+E A
Sbjct: 126 KAALENKLPVVEKFLSD--KNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRD 183
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
++ + + A ++ L+++ ++ D+ T L A+ +G A+ L
Sbjct: 184 -----MLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHL 238
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
+ + ++ +D+ G T + AV N+ +++ +LI GA L + + +T +++
Sbjct: 239 IACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDL 291
>BC028407-1|AAH28407.1| 619|Homo sapiens ankyrin repeat domain 30B
protein.
Length = 619
Score = 58.8 bits (136), Expect = 3e-08
Identities = 49/196 (25%), Positives = 87/196 (44%), Gaps = 8/196 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
+ A G ++ +E + + N N + T L AC + ++V +L+++ N
Sbjct: 42 IHTAASRGQVQKLEKMTVGKKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKCQLNV 101
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
L + TP+M A + + +I LID LN D YG T L A+ S + +
Sbjct: 102 LDGEGRTPLMKALQ---CEREACANI---LIDAGADLNYVDVYGNTALHYAVYSENLLMV 155
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
LL IE++++ T + A+ + +E L+ K A ++S T L +A C
Sbjct: 156 ATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICE 215
Query: 224 DHQVIIEILKKSLNLD 239
I+ +L + N+D
Sbjct: 216 GSSEIVGMLLQQ-NVD 230
Score = 31.5 bits (68), Expect = 4.8
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLI 134
G T L +A + +V LL A + + S+TP++ A S V L+
Sbjct: 139 GNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQT------VEFLL 192
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+N N + T LM AI G + LL V++ D HG TA +A
Sbjct: 193 TKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAACGVNY 252
Query: 195 ILEMLIE 201
I + L+E
Sbjct: 253 IHQQLLE 259
>BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1
(cardiac muscle) protein.
Length = 319
Score = 58.8 bits (136), Expect = 3e-08
Identities = 28/80 (35%), Positives = 46/80 (57%)
Query: 141 NIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI 200
++ D Y +T L RA G +A+ +KL++ IE RD TA+ WA ++L++L+
Sbjct: 147 DVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLL 206
Query: 201 EKGARLTEVDKSNRTLLEIA 220
KGA+++ DK T L +A
Sbjct: 207 NKGAKISARDKLLSTALHVA 226
Score = 42.3 bits (95), Expect = 0.003
Identities = 36/173 (20%), Positives = 80/173 (46%), Gaps = 7/173 (4%)
Query: 47 EAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
+A + + VE +++ KNN ++ + T L AC IV+ L+E A
Sbjct: 126 KAALENKLPVVEKFLSD--KNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRD 183
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
++ + + A ++ L+++ ++ D+ T L A+ +G A+ L
Sbjct: 184 -----MLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHL 238
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
+ + ++ +D+ G T + AV N+ +++ +LI GA L + + +T +++
Sbjct: 239 IACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDL 291
>AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat
domain 1 protein.
Length = 319
Score = 58.8 bits (136), Expect = 3e-08
Identities = 28/80 (35%), Positives = 46/80 (57%)
Query: 141 NIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI 200
++ D Y +T L RA G +A+ +KL++ IE RD TA+ WA ++L++L+
Sbjct: 147 DVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLL 206
Query: 201 EKGARLTEVDKSNRTLLEIA 220
KGA+++ DK T L +A
Sbjct: 207 NKGAKISARDKLLSTALHVA 226
Score = 42.3 bits (95), Expect = 0.003
Identities = 36/173 (20%), Positives = 80/173 (46%), Gaps = 7/173 (4%)
Query: 47 EAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
+A + + VE +++ KNN ++ + T L AC IV+ L+E A
Sbjct: 126 KAALENKLPVVEKFLSD--KNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRD 183
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
++ + + A ++ L+++ ++ D+ T L A+ +G A+ L
Sbjct: 184 -----MLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHL 238
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
+ + ++ +D+ G T + AV N+ +++ +LI GA L + + +T +++
Sbjct: 239 IACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDL 291
>AY172978-1|AAO23914.1| 584|Homo sapiens POTE protein.
Length = 584
Score = 58.8 bits (136), Expect = 3e-08
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 6/162 (3%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
T L A + ++VQ LL++ N+ + + D V L++
Sbjct: 175 TALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDE-----CVLMLLEHG 229
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
NI D YG T L AI + +A+ LL +IE +++ G T + VH + ++++
Sbjct: 230 ADRNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVK 289
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
LI+K A L +D+ RT L +A C I+ +L + N+D
Sbjct: 290 FLIKKKANLNVLDRYGRTALILAVCCGSASIVNLLLEQ-NVD 330
Score = 58.4 bits (135), Expect = 4e-08
Identities = 50/194 (25%), Positives = 90/194 (46%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ V LLE
Sbjct: 171 KEKRTALHLASANGNSEVVQLLLDRRCQ--LNVLDNKKRTALIKAIQCQEDECVLMLLEH 228
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD N+ + A + + D + + L + + ++ G TPL+ +
Sbjct: 229 GADRNIPDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKCGLTPLLLGVHEQ 283
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ + D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 284 KQQVVKFLIKKKANLNVLDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTARE 343
Query: 219 IANCHDHQVIIEIL 232
A H VI E+L
Sbjct: 344 YAVSSHHHVICELL 357
Score = 40.7 bits (91), Expect = 0.008
Identities = 27/97 (27%), Positives = 48/97 (49%)
Query: 136 RNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
R+ +N D+ +T L A ++G V Q LLD + + + D TA+ A+ + E
Sbjct: 162 RDTDMNKRDKEKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDEC 221
Query: 196 LEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ ML+E GA D+ T L A ++ +++ + L
Sbjct: 222 VLMLLEHGADRNIPDEYGNTALHYAIYNEDKLMAKAL 258
Score = 34.7 bits (76), Expect = 0.51
Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N+ I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRTALILAVCCGSA-------SIVNLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + + L D
Sbjct: 325 LEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSD 359
>AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1
(cardiac muscle) protein.
Length = 319
Score = 58.8 bits (136), Expect = 3e-08
Identities = 28/80 (35%), Positives = 46/80 (57%)
Query: 141 NIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLI 200
++ D Y +T L RA G +A+ +KL++ IE RD TA+ WA ++L++L+
Sbjct: 147 DVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLL 206
Query: 201 EKGARLTEVDKSNRTLLEIA 220
KGA+++ DK T L +A
Sbjct: 207 NKGAKISARDKLLSTALHVA 226
Score = 42.3 bits (95), Expect = 0.003
Identities = 36/173 (20%), Positives = 80/173 (46%), Gaps = 7/173 (4%)
Query: 47 EAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
+A + + VE +++ KNN ++ + T L AC IV+ L+E A
Sbjct: 126 KAALENKLPVVEKFLSD--KNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRD 183
Query: 107 DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKL 166
++ + + A ++ L+++ ++ D+ T L A+ +G A+ L
Sbjct: 184 -----MLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHL 238
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
+ + ++ +D+ G T + AV N+ +++ +LI GA L + + +T +++
Sbjct: 239 IACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDL 291
>BC127123-1|AAI27124.1| 581|Homo sapiens protein expressed in
prostate, ovary, testis, and placenta 15 protein.
Length = 581
Score = 58.4 bits (135), Expect = 4e-08
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ V LLE
Sbjct: 171 KQKRTALHLASANGNSEVVQLLLDRRCQ--LNVLDNKKRTALIKAVQCQEDECVLMLLEH 228
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD N+ + A + + D + + L + + ++ G TPL+ +
Sbjct: 229 GADGNIQDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKCGLTPLLLGVHEQ 283
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 284 KQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTARE 343
Query: 219 IANCHDHQVIIEIL 232
A H VI E+L
Sbjct: 344 YAVSSHHHVICELL 357
Score = 58.4 bits (135), Expect = 4e-08
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 6/162 (3%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
T L A + ++VQ LL++ N+ + + D V L++
Sbjct: 175 TALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDE-----CVLMLLEHG 229
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
NI D YG T L AI + +A+ LL +IE +++ G T + VH + ++++
Sbjct: 230 ADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVK 289
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
LI+K A L +D+ RT L +A C I+ +L + N+D
Sbjct: 290 FLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQ-NVD 330
Score = 40.7 bits (91), Expect = 0.008
Identities = 28/97 (28%), Positives = 48/97 (49%)
Query: 136 RNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
R+ +N D+ +T L A ++G V Q LLD + + + D TA+ AV + E
Sbjct: 162 RDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDEC 221
Query: 196 LEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ ML+E GA D+ T L A ++ +++ + L
Sbjct: 222 VLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKAL 258
Score = 33.9 bits (74), Expect = 0.89
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVNLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + + L D
Sbjct: 325 LEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSD 359
>BC101006-1|AAI01007.1| 581|Homo sapiens protein expressed in
prostate, ovary, testis, and placenta 15 protein.
Length = 581
Score = 58.4 bits (135), Expect = 4e-08
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ V LLE
Sbjct: 171 KQKRTALHLASANGNSEVVQLLLDRRCQ--LNVLDNKKRTALIKAVQCQEDECVLMLLEH 228
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD N+ + A + + D + + L + + ++ G TPL+ +
Sbjct: 229 GADGNIQDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKCGLTPLLLGVHEQ 283
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 284 KQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTARE 343
Query: 219 IANCHDHQVIIEIL 232
A H VI E+L
Sbjct: 344 YAVSSHHHVICELL 357
Score = 58.4 bits (135), Expect = 4e-08
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 6/162 (3%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
T L A + ++VQ LL++ N+ + + D V L++
Sbjct: 175 TALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDE-----CVLMLLEHG 229
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
NI D YG T L AI + +A+ LL +IE +++ G T + VH + ++++
Sbjct: 230 ADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVK 289
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
LI+K A L +D+ RT L +A C I+ +L + N+D
Sbjct: 290 FLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQ-NVD 330
Score = 40.7 bits (91), Expect = 0.008
Identities = 28/97 (28%), Positives = 48/97 (49%)
Query: 136 RNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
R+ +N D+ +T L A ++G V Q LLD + + + D TA+ AV + E
Sbjct: 162 RDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDEC 221
Query: 196 LEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ ML+E GA D+ T L A ++ +++ + L
Sbjct: 222 VLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKAL 258
Score = 33.9 bits (74), Expect = 0.89
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVNLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + + L D
Sbjct: 325 LEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSD 359
>BC101005-1|AAI01006.1| 544|Homo sapiens POTE15 protein protein.
Length = 544
Score = 58.4 bits (135), Expect = 4e-08
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ V LLE
Sbjct: 134 KQKRTALHLASANGNSEVVQLLLDRRCQ--LNVLDNKKRTALIKAVQCQEDECVLMLLEH 191
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD N+ + A + + D + + L + + ++ G TPL+ +
Sbjct: 192 GADGNIQDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKCGLTPLLLGVHEQ 246
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 247 KQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTARE 306
Query: 219 IANCHDHQVIIEIL 232
A H VI E+L
Sbjct: 307 YAVSSHHHVICELL 320
Score = 58.4 bits (135), Expect = 4e-08
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 6/162 (3%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
T L A + ++VQ LL++ N+ + + D V L++
Sbjct: 138 TALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDE-----CVLMLLEHG 192
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
NI D YG T L AI + +A+ LL +IE +++ G T + VH + ++++
Sbjct: 193 ADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVK 252
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
LI+K A L +D+ RT L +A C I+ +L + N+D
Sbjct: 253 FLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQ-NVD 293
Score = 40.7 bits (91), Expect = 0.008
Identities = 28/97 (28%), Positives = 48/97 (49%)
Query: 136 RNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
R+ +N D+ +T L A ++G V Q LLD + + + D TA+ AV + E
Sbjct: 125 RDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDEC 184
Query: 196 LEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ ML+E GA D+ T L A ++ +++ + L
Sbjct: 185 VLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKAL 221
Score = 33.9 bits (74), Expect = 0.89
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 235 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVNLL 287
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + + L D
Sbjct: 288 LEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSD 322
>BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 909
Score = 58.4 bits (135), Expect = 4e-08
Identities = 51/172 (29%), Positives = 84/172 (48%), Gaps = 9/172 (5%)
Query: 50 INGNMKDVEDLINNELKN-NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSD 107
I N VE L+ K N N + SG TPL A + Q K + LLE AD N+ +++
Sbjct: 71 IAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNE 130
Query: 108 SVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLL 167
+T I N + ++ +V ++ D +++ D GQT L A +G Q LL
Sbjct: 131 GLTAIHWLAVNGRTE--LLHDLVQHVSD----VDVEDAMGQTALHVACQNGHKTTVQCLL 184
Query: 168 DMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
D +I + G T +++A H Q + ++L+ +GA+ DK+ T L++
Sbjct: 185 DSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLP-DKNGVTPLDL 235
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/103 (25%), Positives = 49/103 (47%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ + N D G TPL A +G+ KLL+ ++ + + G TA+ W + +
Sbjct: 84 LLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGR 143
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKS 235
E+L L++ + + D +T L +A + H+ ++ L S
Sbjct: 144 TELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDS 186
Score = 44.4 bits (100), Expect = 6e-04
Identities = 42/190 (22%), Positives = 80/190 (42%), Gaps = 9/190 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L ++ + V +L++N K + N L+H + + + LL+K A+PN
Sbjct: 34 LMPMVMADQHRSVSELLSNS-KFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPN 92
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
S TP+ A N + L++ + +NI + G T + +GR +
Sbjct: 93 YQDISGCTPLHLAARNGQK------KCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTEL 146
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
L+ ++++ D G TA+ A + ++ L++ GA + + S T L A
Sbjct: 147 LHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACS 206
Query: 223 HDHQVIIEIL 232
H + +IL
Sbjct: 207 HGQRDTAQIL 216
>AY465173-1|AAS58872.1| 581|Homo sapiens POTE15A protein.
Length = 581
Score = 58.4 bits (135), Expect = 4e-08
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ V LLE
Sbjct: 171 KQKRTALHLASANGNSEVVQLLLDRRCQ--LNVLDNKKRTALIKAVQCQEDECVLMLLEH 228
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD N+ + A + + D + + L + + ++ G TPL+ +
Sbjct: 229 GADGNIQDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKCGLTPLLLGVHEQ 283
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 284 KQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTARE 343
Query: 219 IANCHDHQVIIEIL 232
A H VI E+L
Sbjct: 344 YAVSSHHHVICELL 357
Score = 58.4 bits (135), Expect = 4e-08
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 6/162 (3%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
T L A + ++VQ LL++ N+ + + D V L++
Sbjct: 175 TALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDE-----CVLMLLEHG 229
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
NI D YG T L AI + +A+ LL +IE +++ G T + VH + ++++
Sbjct: 230 ADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVK 289
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
LI+K A L +D+ RT L +A C I+ +L + N+D
Sbjct: 290 FLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQ-NVD 330
Score = 40.7 bits (91), Expect = 0.008
Identities = 28/97 (28%), Positives = 48/97 (49%)
Query: 136 RNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
R+ +N D+ +T L A ++G V Q LLD + + + D TA+ AV + E
Sbjct: 162 RDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDEC 221
Query: 196 LEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ ML+E GA D+ T L A ++ +++ + L
Sbjct: 222 VLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKAL 258
Score = 33.9 bits (74), Expect = 0.89
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 272 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVNLL 324
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + + L D
Sbjct: 325 LEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSD 359
>AY465170-1|AAS58869.1| 544|Homo sapiens POTE15B protein.
Length = 544
Score = 58.4 bits (135), Expect = 4e-08
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A NGN + V+ L++ + N+ + T L+ A +D+ V LLE
Sbjct: 134 KQKRTALHLASANGNSEVVQLLLDRRCQ--LNVLDNKKRTALIKAVQCQEDECVLMLLEH 191
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD N+ + A + + D + + L + + ++ G TPL+ +
Sbjct: 192 GADGNIQDEYGN---TALHYAIYNEDKLMAKALLLYGAD--IESKNKCGLTPLLLGVHEQ 246
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+ V + L+ + N+ D++G TA+ AV I+ +L+E+ ++ D S +T E
Sbjct: 247 KQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTARE 306
Query: 219 IANCHDHQVIIEIL 232
A H VI E+L
Sbjct: 307 YAVSSHHHVICELL 320
Score = 58.4 bits (135), Expect = 4e-08
Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 6/162 (3%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
T L A + ++VQ LL++ N+ + + D V L++
Sbjct: 138 TALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDE-----CVLMLLEHG 192
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
NI D YG T L AI + +A+ LL +IE +++ G T + VH + ++++
Sbjct: 193 ADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVK 252
Query: 198 MLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLD 239
LI+K A L +D+ RT L +A C I+ +L + N+D
Sbjct: 253 FLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQ-NVD 293
Score = 40.7 bits (91), Expect = 0.008
Identities = 28/97 (28%), Positives = 48/97 (49%)
Query: 136 RNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEI 195
R+ +N D+ +T L A ++G V Q LLD + + + D TA+ AV + E
Sbjct: 125 RDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDEC 184
Query: 196 LEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ ML+E GA D+ T L A ++ +++ + L
Sbjct: 185 VLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKAL 221
Score = 33.9 bits (74), Expect = 0.89
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNL--HSDSVTPIMAACSNSSADNDTIYSIVCNL 133
G TPL+ + ++V++L++K A+ N I+A C S+ SIV L
Sbjct: 235 GLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSA-------SIVNLL 287
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD 168
+++N ++ D GQT A+SS + + L D
Sbjct: 288 LEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSD 322
>BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 58.0 bits (134), Expect = 5e-08
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 18/204 (8%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
A+Q A NG++ D++ LK N +++ + G + HA F + +++ L AD
Sbjct: 467 AMQAASQNGHV----DILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSAD 522
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
N + TP+ A + +V L+D C ++ D G TPL AIS R
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQ------VVKTLLDFGCHPSLQDSEGDTPLHDAISKKRD 576
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK---SNRTLL 217
+ LL+ ++ + + +G+ A+ A P + +L+ K R VD+ T L
Sbjct: 577 DILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTAL 636
Query: 218 EIANCHDHQVIIEIL--KKSLNLD 239
+A ++H + E+L + + NLD
Sbjct: 637 HLAALNNHVEVAELLVHQGNANLD 660
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 9/193 (4%)
Query: 45 LQEAIINGNMKDVEDLINN-ELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L +A NG++ VEDL+ ++ N +G T + A + I++ LL+++ D
Sbjct: 435 LVKAAANGDVAKVEDLLKRPDVDVNGQC---AGHTAMQAASQNGHVDILKLLLKQNVD-- 489
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ ++ A + D + + L + LN ++ QTPL A++ G + V
Sbjct: 490 VEAEDKDGDRAVHHAAFGDEGAVIEV---LHRGSADLNARNKRRQTPLHIAVNKGHLQVV 546
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ LLD + ++D G T + A+ + +IL +L+E GA +T + + L A
Sbjct: 547 KTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALR 606
Query: 224 DHQVIIEILKKSL 236
+ + +L L
Sbjct: 607 GNPSAMRVLLSKL 619
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/186 (24%), Positives = 88/186 (47%), Gaps = 5/186 (2%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ + L A+ G+++ V+ L+ + + +++ G TPL A +D I+ LLE
Sbjct: 528 KRRQTPLHIAVNKGHLQVVKTLL--DFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEA 585
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD + +++ A + N + ++ + + R I++ G T L A +
Sbjct: 586 GADVTITNNN--GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNN 643
Query: 159 RVAVAQKLLDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V VA+ L+ N+++++ + TA+ AV +I+ +L+ GA+L DK T L
Sbjct: 644 HVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPL 703
Query: 218 EIANCH 223
A H
Sbjct: 704 HEALRH 709
>BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 58.0 bits (134), Expect = 5e-08
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 18/204 (8%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
A+Q A NG++ D++ LK N +++ + G + HA F + +++ L AD
Sbjct: 467 AMQAASQNGHV----DILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSAD 522
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
N + TP+ A + +V L+D C ++ D G TPL AIS R
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQ------VVKTLLDFGCHPSLQDSEGDTPLHDAISKKRD 576
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK---SNRTLL 217
+ LL+ ++ + + +G+ A+ A P + +L+ K R VD+ T L
Sbjct: 577 DILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTAL 636
Query: 218 EIANCHDHQVIIEIL--KKSLNLD 239
+A ++H + E+L + + NLD
Sbjct: 637 HLAALNNHVEVAELLVHQGNANLD 660
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 9/193 (4%)
Query: 45 LQEAIINGNMKDVEDLINN-ELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L +A NG++ VEDL+ ++ N +G T + A + I++ LL+++ D
Sbjct: 435 LVKAAANGDVAKVEDLLKRPDVDVNGQC---AGHTAMQAASQNGHVDILKLLLKQNVD-- 489
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ ++ A + D + + L + LN ++ QTPL A++ G + V
Sbjct: 490 VEAEDKDGDRAVHHAAFGDEGAVIEV---LHRGSADLNARNKRRQTPLHIAVNKGHLQVV 546
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ LLD + ++D G T + A+ + +IL +L+E GA +T + + L A
Sbjct: 547 KTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALR 606
Query: 224 DHQVIIEILKKSL 236
+ + +L L
Sbjct: 607 GNPSAMRVLLSKL 619
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/186 (24%), Positives = 88/186 (47%), Gaps = 5/186 (2%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ + L A+ G+++ V+ L+ + + +++ G TPL A +D I+ LLE
Sbjct: 528 KRRQTPLHIAVNKGHLQVVKTLL--DFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEA 585
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD + +++ A + N + ++ + + R I++ G T L A +
Sbjct: 586 GADVTITNNN--GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNN 643
Query: 159 RVAVAQKLLDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V VA+ L+ N+++++ + TA+ AV +I+ +L+ GA+L DK T L
Sbjct: 644 HVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPL 703
Query: 218 EIANCH 223
A H
Sbjct: 704 HEALRH 709
>AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein.
Length = 1006
Score = 58.0 bits (134), Expect = 5e-08
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 18/204 (8%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
A+Q A NG++ D++ LK N +++ + G + HA F + +++ L AD
Sbjct: 467 AMQAASQNGHV----DILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSAD 522
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
N + TP+ A + +V L+D C ++ D G TPL AIS R
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQ------VVKTLLDFGCHPSLQDSEGDTPLHDAISKKRD 576
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK---SNRTLL 217
+ LL+ ++ + + +G+ A+ A P + +L+ K R VD+ T L
Sbjct: 577 DILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTAL 636
Query: 218 EIANCHDHQVIIEIL--KKSLNLD 239
+A ++H + E+L + + NLD
Sbjct: 637 HLAALNNHVEVAELLVHQGNANLD 660
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 9/193 (4%)
Query: 45 LQEAIINGNMKDVEDLINN-ELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L +A NG++ VEDL+ ++ N +G T + A + I++ LL+++ D
Sbjct: 435 LVKAAANGDVAKVEDLLKRPDVDVNGQC---AGHTAMQAASQNGHVDILKLLLKQNVD-- 489
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ ++ A + D + + L + LN ++ QTPL A++ G + V
Sbjct: 490 VEAEDKDGDRAVHHAAFGDEGAVIEV---LHRGSADLNARNKRRQTPLHIAVNKGHLQVV 546
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ LLD + ++D G T + A+ + +IL +L+E GA +T + + L A
Sbjct: 547 KTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALR 606
Query: 224 DHQVIIEILKKSL 236
+ + +L L
Sbjct: 607 GNPSAMRVLLSKL 619
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/186 (24%), Positives = 88/186 (47%), Gaps = 5/186 (2%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ + L A+ G+++ V+ L+ + + +++ G TPL A +D I+ LLE
Sbjct: 528 KRRQTPLHIAVNKGHLQVVKTLL--DFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEA 585
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD + +++ A + N + ++ + + R I++ G T L A +
Sbjct: 586 GADVTITNNN--GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNN 643
Query: 159 RVAVAQKLLDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V VA+ L+ N+++++ + TA+ AV +I+ +L+ GA+L DK T L
Sbjct: 644 HVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPL 703
Query: 218 EIANCH 223
A H
Sbjct: 704 HEALRH 709
>AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein.
Length = 997
Score = 58.0 bits (134), Expect = 5e-08
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 18/204 (8%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
A+Q A NG++ D++ LK N +++ + G + HA F + +++ L AD
Sbjct: 458 AMQAASQNGHV----DILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSAD 513
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
N + TP+ A + +V L+D C ++ D G TPL AIS R
Sbjct: 514 LNARNKRRQTPLHIAVNKGHLQ------VVKTLLDFGCHPSLQDSEGDTPLHDAISKKRD 567
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK---SNRTLL 217
+ LL+ ++ + + +G+ A+ A P + +L+ K R VD+ T L
Sbjct: 568 DILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTAL 627
Query: 218 EIANCHDHQVIIEIL--KKSLNLD 239
+A ++H + E+L + + NLD
Sbjct: 628 HLAALNNHVEVAELLVHQGNANLD 651
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 9/193 (4%)
Query: 45 LQEAIINGNMKDVEDLINN-ELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
L +A NG++ VEDL+ ++ N +G T + A + I++ LL+++ D
Sbjct: 426 LVKAAANGDVAKVEDLLKRPDVDVNGQC---AGHTAMQAASQNGHVDILKLLLKQNVD-- 480
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ ++ A + D + + L + LN ++ QTPL A++ G + V
Sbjct: 481 VEAEDKDGDRAVHHAAFGDEGAVIEV---LHRGSADLNARNKRRQTPLHIAVNKGHLQVV 537
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ LLD + ++D G T + A+ + +IL +L+E GA +T + + L A
Sbjct: 538 KTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALR 597
Query: 224 DHQVIIEILKKSL 236
+ + +L L
Sbjct: 598 GNPSAMRVLLSKL 610
Score = 50.4 bits (115), Expect = 1e-05
Identities = 46/186 (24%), Positives = 88/186 (47%), Gaps = 5/186 (2%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ + L A+ G+++ V+ L+ + + +++ G TPL A +D I+ LLE
Sbjct: 519 KRRQTPLHIAVNKGHLQVVKTLL--DFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEA 576
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
AD + +++ A + N + ++ + + R I++ G T L A +
Sbjct: 577 GADVTITNNN--GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNN 634
Query: 159 RVAVAQKLLDM-QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V VA+ L+ N+++++ + TA+ AV +I+ +L+ GA+L DK T L
Sbjct: 635 HVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPL 694
Query: 218 EIANCH 223
A H
Sbjct: 695 HEALRH 700
>BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.
Length = 1726
Score = 57.6 bits (133), Expect = 6e-08
Identities = 49/205 (23%), Positives = 96/205 (46%), Gaps = 8/205 (3%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
+ +A GN+ V+ ++ KN N + T L AC + ++V L+++ N+
Sbjct: 50 IHKAASAGNVAKVQQILLLR-KNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNV 108
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+++ T +M A TI L++ N+ D +G T L A+ + ++VA
Sbjct: 109 CDNENRTALMKAVQCQEEKCATI------LLEHGADPNLADVHGNTALHYAVYNEDISVA 162
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
KLL NIE +++ T + AV + +++E LI+K A + VDK + I+
Sbjct: 163 TKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYK 222
Query: 224 DHQVIIEILKKSLNLDDDHKTDENS 248
+ ++ + S ++D+ + +S
Sbjct: 223 EERIPKHSSQNSNSVDESSEDSLSS 247
Score = 57.2 bits (132), Expect = 8e-08
Identities = 45/163 (27%), Positives = 78/163 (47%), Gaps = 11/163 (6%)
Query: 95 LLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRA 154
LL K+ + + T + AC+N + +V L+DR C LN+ D +T LM+A
Sbjct: 67 LLRKNGLNDRDKMNRTALHLACANGHPE------VVTLLVDRKCQLNVCDNENRTALMKA 120
Query: 155 ISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR 214
+ A LL+ + + D HG TA+ +AV++ + L+ A + +K +
Sbjct: 121 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL 180
Query: 215 TLLEIANCHDHQVIIE-ILKKSLNLDDDHKTDENSYLNHQLTS 256
T L +A Q ++E ++KK N++ K + +HQL S
Sbjct: 181 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLES----SHQLIS 219
>BC128517-1|AAI28518.1| 309|Homo sapiens ANKRD36 protein protein.
Length = 309
Score = 57.6 bits (133), Expect = 6e-08
Identities = 44/159 (27%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
A H + ++YLL D N T + AC+ + +V L+ R C LN
Sbjct: 39 AVLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPE------MVHLLVSRRCELN 92
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ DR +TPL++A+ + A A LL N + D G TA+ +AV++ ++E L+
Sbjct: 93 LCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLS 152
Query: 202 KGARLTEVDKSN-RTLLEIANCHDHQVIIEILKKSLNLD 239
G + E K + LL + +++ +LKK N++
Sbjct: 153 HGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVN 191
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/196 (21%), Positives = 94/196 (47%), Gaps = 10/196 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
+ A+++GN++ ++ L+ N + + T L AC Q ++V L+ + + NL
Sbjct: 36 IHRAVLHGNLEKLKYLLLTYYDANKRDRKER--TALHLACATGQPEMVHLLVSRRCELNL 93
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ TP++ A T+ L+ NI D +G+T L A+ + ++
Sbjct: 94 CDREDRTPLIKAVQLRQEACATL------LLQNGANPNITDFFGRTALHYAVYNEDTSMI 147
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-LLEIANC 222
+KLL NIE + + + +AV + +++E L++K A + +D R+ L+
Sbjct: 148 EKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTL 207
Query: 223 HDHQVIIEILKKSLNL 238
+ ++I +L+ ++++
Sbjct: 208 GEKDIVILLLQHNIDV 223
Score = 39.9 bits (89), Expect = 0.014
Identities = 44/194 (22%), Positives = 86/194 (44%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K AL A G + V L++ + N + D TPL+ A Q+ LL+
Sbjct: 63 RKERTALHLACATGQPEMVHLLVSRRCELNLCDREDR--TPLIKAVQLRQEACATLLLQN 120
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
A+PN+ +D A + + DT S++ L+ + + PL+ A+S
Sbjct: 121 GANPNI-TDFFG--RTALHYAVYNEDT--SMIEKLLSHGTNIEECSKCEYQPLLFAVSRR 175
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+V + + LL + N+ D G +A+ AV + +I+ +L++ + D + +
Sbjct: 176 KVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGD 235
Query: 219 IANCHDHQVIIEIL 232
A ++VI +++
Sbjct: 236 YAIEAKNRVIFDLI 249
>BC128262-1|AAI28263.1| 346|Homo sapiens ANKRD36 protein protein.
Length = 346
Score = 57.6 bits (133), Expect = 6e-08
Identities = 44/159 (27%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
A H + ++YLL D N T + AC+ + +V L+ R C LN
Sbjct: 39 AVLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPE------MVHLLVSRRCELN 92
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ DR +TPL++A+ + A A LL N + D G TA+ +AV++ ++E L+
Sbjct: 93 LCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLS 152
Query: 202 KGARLTEVDKSN-RTLLEIANCHDHQVIIEILKKSLNLD 239
G + E K + LL + +++ +LKK N++
Sbjct: 153 HGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVN 191
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/196 (21%), Positives = 94/196 (47%), Gaps = 10/196 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
+ A+++GN++ ++ L+ N + + T L AC Q ++V L+ + + NL
Sbjct: 36 IHRAVLHGNLEKLKYLLLTYYDANKRDRKER--TALHLACATGQPEMVHLLVSRRCELNL 93
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ TP++ A T+ L+ NI D +G+T L A+ + ++
Sbjct: 94 CDREDRTPLIKAVQLRQEACATL------LLQNGANPNITDFFGRTALHYAVYNEDTSMI 147
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-LLEIANC 222
+KLL NIE + + + +AV + +++E L++K A + +D R+ L+
Sbjct: 148 EKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTL 207
Query: 223 HDHQVIIEILKKSLNL 238
+ ++I +L+ ++++
Sbjct: 208 GEKDIVILLLQHNIDV 223
Score = 39.9 bits (89), Expect = 0.014
Identities = 44/194 (22%), Positives = 86/194 (44%), Gaps = 7/194 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K AL A G + V L++ + N + D TPL+ A Q+ LL+
Sbjct: 63 RKERTALHLACATGQPEMVHLLVSRRCELNLCDREDR--TPLIKAVQLRQEACATLLLQN 120
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
A+PN+ +D A + + DT S++ L+ + + PL+ A+S
Sbjct: 121 GANPNI-TDFFG--RTALHYAVYNEDT--SMIEKLLSHGTNIEECSKCEYQPLLFAVSRR 175
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+V + + LL + N+ D G +A+ AV + +I+ +L++ + D + +
Sbjct: 176 KVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGD 235
Query: 219 IANCHDHQVIIEIL 232
A ++VI +++
Sbjct: 236 YAIEAKNRVIFDLI 249
>BC098312-1|AAH98312.1| 851|Homo sapiens ANKRD25 protein protein.
Length = 851
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP--NLHSDSVTPIMAACSNSSADNDTIY 127
NI +G T L ++ HA +VQ LL+ + +PIM + D I
Sbjct: 661 NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIE 720
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
+++ L I + GQT LM A+S GRV V + LL + ++ ++D G TA+ A
Sbjct: 721 TVL-QLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCA 779
Query: 188 VHHNQPEILEMLIE-KGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNL 238
H EI +L+ ++ D+ T L +A I +L +N+
Sbjct: 780 CEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNI 831
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 139 ILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV-NIEMRDQHGW-----TAVFWAVHHNQ 192
++NI D G T L ++S V Q+LLD V ++ +++ G+ TA+ +
Sbjct: 659 VVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDD 718
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL---KKSLNLDDD 241
E + L G + ++ +T L +A H +++ L + +N+ DD
Sbjct: 719 IETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDD 770
>BC098286-1|AAH98286.1| 851|Homo sapiens ANKRD25 protein protein.
Length = 851
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP--NLHSDSVTPIMAACSNSSADNDTIY 127
NI +G T L ++ HA +VQ LL+ + +PIM + D I
Sbjct: 661 NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIE 720
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
+++ L I + GQT LM A+S GRV V + LL + ++ ++D G TA+ A
Sbjct: 721 TVL-QLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCA 779
Query: 188 VHHNQPEILEMLIE-KGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNL 238
H EI +L+ ++ D+ T L +A I +L +N+
Sbjct: 780 CEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNI 831
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 139 ILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV-NIEMRDQHGW-----TAVFWAVHHNQ 192
++NI D G T L ++S V Q+LLD V ++ +++ G+ TA+ +
Sbjct: 659 VVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDD 718
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL---KKSLNLDDD 241
E + L G + ++ +T L +A H +++ L + +N+ DD
Sbjct: 719 IETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDD 770
>BC098105-1|AAH98105.1| 851|Homo sapiens ANKRD25 protein protein.
Length = 851
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP--NLHSDSVTPIMAACSNSSADNDTIY 127
NI +G T L ++ HA +VQ LL+ + +PIM + D I
Sbjct: 661 NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIE 720
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
+++ L I + GQT LM A+S GRV V + LL + ++ ++D G TA+ A
Sbjct: 721 TVL-QLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCA 779
Query: 188 VHHNQPEILEMLIE-KGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNL 238
H EI +L+ ++ D+ T L +A I +L +N+
Sbjct: 780 CEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNI 831
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 139 ILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV-NIEMRDQHGW-----TAVFWAVHHNQ 192
++NI D G T L ++S V Q+LLD V ++ +++ G+ TA+ +
Sbjct: 659 VVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDD 718
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL---KKSLNLDDD 241
E + L G + ++ +T L +A H +++ L + +N+ DD
Sbjct: 719 IETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDD 770
>BC082762-1|AAH82762.1| 851|Homo sapiens ANKRD25 protein protein.
Length = 851
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP--NLHSDSVTPIMAACSNSSADNDTIY 127
NI +G T L ++ HA +VQ LL+ + +PIM + D I
Sbjct: 661 NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIE 720
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
+++ L I + GQT LM A+S GRV V + LL + ++ ++D G TA+ A
Sbjct: 721 TVL-QLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCA 779
Query: 188 VHHNQPEILEMLIE-KGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNL 238
H EI +L+ ++ D+ T L +A I +L +N+
Sbjct: 780 CEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNI 831
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 139 ILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV-NIEMRDQHGW-----TAVFWAVHHNQ 192
++NI D G T L ++S V Q+LLD V ++ +++ G+ TA+ +
Sbjct: 659 VVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDD 718
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL---KKSLNLDDD 241
E + L G + ++ +T L +A H +++ L + +N+ DD
Sbjct: 719 IETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDD 770
>AY639929-1|AAT57879.1| 859|Homo sapiens SRC-1 interacting protein
protein.
Length = 859
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP--NLHSDSVTPIMAACSNSSADNDTIY 127
NI +G T L ++ HA +VQ LL+ + +PIM + D I
Sbjct: 669 NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIE 728
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
+++ L I + GQT LM A+S GRV V + LL + ++ ++D G TA+ A
Sbjct: 729 TVL-QLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCA 787
Query: 188 VHHNQPEILEMLIE-KGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNL 238
H EI +L+ ++ D+ T L +A I +L +N+
Sbjct: 788 CEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNI 839
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 139 ILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV-NIEMRDQHGW-----TAVFWAVHHNQ 192
++NI D G T L ++S V Q+LLD V ++ +++ G+ TA+ +
Sbjct: 667 VVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDD 726
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL---KKSLNLDDD 241
E + L G + ++ +T L +A H +++ L + +N+ DD
Sbjct: 727 IETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDD 778
>AK023332-1|BAB14531.1| 454|Homo sapiens protein ( Homo sapiens
cDNA FLJ13270 fis, clone OVARC1000999, weakly similar to
ANKYRIN HOMOLOG PRECURSOR. ).
Length = 454
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP--NLHSDSVTPIMAACSNSSADNDTIY 127
NI +G T L ++ HA +VQ LL+ + +PIM + D I
Sbjct: 274 NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIE 333
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
+++ L I + GQT LM A+S GRV V + LL + ++ ++D G TA+ A
Sbjct: 334 TVL-QLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCA 392
Query: 188 VHHNQPEILEMLIE-KGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNL 238
H EI +L+ ++ D+ T L +A I +L +N+
Sbjct: 393 CEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNI 444
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 139 ILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV-NIEMRDQHGW-----TAVFWAVHHNQ 192
++NI D G T L ++S V Q+LLD V ++ +++ G+ TA+ +
Sbjct: 272 VVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDD 331
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL---KKSLNLDDD 241
E + L G + ++ +T L +A H +++ L + +N+ DD
Sbjct: 332 IETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDD 383
Score = 30.7 bits (66), Expect = 8.3
Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLE-KDA 100
+ AL A+ +G + V+ L+ E + N++ D G T LM AC H +I LL
Sbjct: 353 QTALMLAVSHGRVDVVKALLACEA--DVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSC 410
Query: 101 DPNL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI 142
D +L D T +M A A I S++ + ++ C +++
Sbjct: 411 DISLTDRDGSTALMVAL---DAGQSEIASMLYSRMNIKCSVSL 450
>AK002094-1|BAA92081.1| 369|Homo sapiens protein ( Homo sapiens
cDNA FLJ11232 fis, clone PLACE1008429, weakly similar to
ANKYRIN HOMOLOG PRECURSOR. ).
Length = 369
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP--NLHSDSVTPIMAACSNSSADNDTIY 127
NI +G T L ++ HA +VQ LL+ + +PIM + D I
Sbjct: 179 NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIE 238
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
+++ L I + GQT LM A+S GRV V + LL + ++ ++D G TA+ A
Sbjct: 239 TVL-QLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCA 297
Query: 188 VHHNQPEILEMLIE-KGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNL 238
H EI +L+ ++ D+ T L +A I +L +N+
Sbjct: 298 CEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNI 349
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 139 ILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV-NIEMRDQHGW-----TAVFWAVHHNQ 192
++NI D G T L ++S V Q+LLD V ++ +++ G+ TA+ +
Sbjct: 177 VVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDD 236
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL---KKSLNLDDD 241
E + L G + ++ +T L +A H +++ L + +N+ DD
Sbjct: 237 IETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDD 288
>AB040951-1|BAA96042.2| 876|Homo sapiens KIAA1518 protein protein.
Length = 876
Score = 57.6 bits (133), Expect = 6e-08
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADP--NLHSDSVTPIMAACSNSSADNDTIY 127
NI +G T L ++ HA +VQ LL+ + +PIM + D I
Sbjct: 686 NIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIE 745
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
+++ L I + GQT LM A+S GRV V + LL + ++ ++D G TA+ A
Sbjct: 746 TVL-QLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCA 804
Query: 188 VHHNQPEILEMLIE-KGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNL 238
H EI +L+ ++ D+ T L +A I +L +N+
Sbjct: 805 CEHGHKEIAGLLLAVPSCDISLTDRDGSTALMVALDAGQSEIASMLYSRMNI 856
Score = 32.3 bits (70), Expect = 2.7
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
Query: 139 ILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV-NIEMRDQHGW-----TAVFWAVHHNQ 192
++NI D G T L ++S V Q+LLD V ++ +++ G+ TA+ +
Sbjct: 684 VVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDD 743
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL---KKSLNLDDD 241
E + L G + ++ +T L +A H +++ L + +N+ DD
Sbjct: 744 IETVLQLFRLGNINAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDD 795
>L10381-1|AAA18032.1| 741|Homo sapiens 2-5A-dependent RNase
protein.
Length = 741
Score = 57.2 bits (132), Expect = 8e-08
Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 23/198 (11%)
Query: 36 SSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKL---DSGWTPLMHACFHAQDKIV 92
SS ++ V +I + DL+ L+ AN+ + GWTPL +A +++ IV
Sbjct: 16 SSGRRAAVEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIV 75
Query: 93 QYLLEKDADPNLH-SDSVTP-IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTP 150
+ LL ADP L + TP I+AA + S ++ + + +N D YG T
Sbjct: 76 ELLLRHGADPVLRKKNGATPFILAAIAGS-------VKLLKLFLSKGADVNECDFYGFTA 128
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMR-----DQH-----GWTAVFWAVHHNQPEILEMLI 200
M A G+V + L N+ +R DQ G TA+ A E+L++L+
Sbjct: 129 FMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL 188
Query: 201 -EKGARLTEVDKSNRTLL 217
E GA + D R L
Sbjct: 189 DEMGADVNACDNMGRNAL 206
Score = 53.2 bits (122), Expect = 1e-06
Identities = 47/174 (27%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLL-EKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
G T LM A ++++ LL E AD N + + SS D+D + +I L+
Sbjct: 168 GATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSD-VEAITHLLL 226
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP 193
D +N+ G+TPL+ A+ + + Q+LL+ + + I D G TA+ AV
Sbjct: 227 DHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLK 286
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDEN 247
+I E+L ++GA D + + N +DH ++ +L +D H E+
Sbjct: 287 KIAELLCKRGA---STDCGDLVMTARRN-YDHSLVKVLLSHGAK-EDFHPPAED 335
>DQ309791-1|ABC48694.1| 871|Homo sapiens SamCystin protein.
Length = 871
Score = 57.2 bits (132), Expect = 8e-08
Identities = 27/81 (33%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQ-HGWTAVFWAVHHNQPEILEM 198
+N+ + G TPLM A +G++A+ Q L++ +++ +D HGWTA+ A +H EI++
Sbjct: 319 VNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKY 378
Query: 199 LIEKGARLTEVDKSNRTLLEI 219
L+ +GA +T K+ T ++
Sbjct: 379 LLNQGADVTLRAKNGYTAFDL 399
Score = 45.2 bits (102), Expect = 4e-04
Identities = 22/103 (21%), Positives = 50/103 (48%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
++ D G T L A + G + + LL ++ R+ +GW+A+ A + +L
Sbjct: 71 VDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLL 130
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDH 242
++ GA + ++ ++L +A+ H ++++L ++ D H
Sbjct: 131 LDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHH 173
Score = 37.9 bits (84), Expect = 0.055
Identities = 21/72 (29%), Positives = 39/72 (54%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ R +N + YG + LM+A G V+VA LLD ++ +++ G + + A
Sbjct: 97 LLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGH 156
Query: 193 PEILEMLIEKGA 204
++++L+E GA
Sbjct: 157 LGVVKLLLEAGA 168
Score = 37.1 bits (82), Expect = 0.096
Identities = 49/215 (22%), Positives = 85/215 (39%), Gaps = 18/215 (8%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
ALQ A G+ E L+ L+ A++ + GW+ LM A + LL+ AD
Sbjct: 81 ALQFAAAGGH----EPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGAD 136
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCN-LIDRNCI----LNIGDRYGQ----TPLM 152
N + ++ S + +D + L +G + T LM
Sbjct: 137 VNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHPSGEQLGLGGSRDEPLDITALM 196
Query: 153 RAISSGRVAVAQKLLDMQVNIEMRDQH-GWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
AI G AV + L++ + + GW+ + A + + + L+EKGA +
Sbjct: 197 AAIQHGHEAVVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSV 256
Query: 212 SNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDE 246
+T E+A H+ +++ L + KTDE
Sbjct: 257 LEKTAFEVALDCKHRDLVDYLDPLTTVRP--KTDE 289
Score = 37.1 bits (82), Expect = 0.096
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 60 LINNELKNNANI-KLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
L+ ++ +A++ K DS GWT LM A +H +IV+YLL + AD L +
Sbjct: 341 LVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRA 390
Score = 35.9 bits (79), Expect = 0.22
Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 9/118 (7%)
Query: 80 LMHACFHAQDKIVQYLLEKD-ADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
+ HA ++V+ + ++D + NL + D TP+M A ++V L++R+
Sbjct: 296 IFHALKMGNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQL------ALVQLLVERH 349
Query: 138 CILNIGDR-YGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ D +G T LM+A G + + LL+ ++ +R ++G+TA + N P+
Sbjct: 350 ADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTAFDLVMLLNDPD 407
Score = 31.1 bits (67), Expect = 6.3
Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A+ GN + V+++ + + ++ N+ G TPLM A Q +VQ L+E+ AD + D
Sbjct: 299 ALKMGNFQLVKEIADED-PSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVD-KQD 356
Query: 108 SV 109
SV
Sbjct: 357 SV 358
>BC115697-1|AAI15698.1| 741|Homo sapiens ribonuclease L
(2',5'-oligoisoadenylate synthetase-dependent) protein.
Length = 741
Score = 57.2 bits (132), Expect = 8e-08
Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 23/198 (11%)
Query: 36 SSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKL---DSGWTPLMHACFHAQDKIV 92
SS ++ V +I + DL+ L+ AN+ + GWTPL +A +++ IV
Sbjct: 16 SSGRRAAVEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIV 75
Query: 93 QYLLEKDADPNLH-SDSVTP-IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTP 150
+ LL ADP L + TP I+AA + S ++ + + +N D YG T
Sbjct: 76 ELLLRHGADPVLRKKNGATPFILAAIAGS-------VKLLKLFLSKGADVNECDFYGFTA 128
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMR-----DQH-----GWTAVFWAVHHNQPEILEMLI 200
M A G+V + L N+ +R DQ G TA+ A E+L++L+
Sbjct: 129 FMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL 188
Query: 201 -EKGARLTEVDKSNRTLL 217
E GA + D R L
Sbjct: 189 DEMGADVNACDNMGRNAL 206
Score = 53.2 bits (122), Expect = 1e-06
Identities = 47/174 (27%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLL-EKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
G T LM A ++++ LL E AD N + + SS D+D + +I L+
Sbjct: 168 GATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSD-VEAITHLLL 226
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP 193
D +N+ G+TPL+ A+ + + Q+LL+ + + I D G TA+ AV
Sbjct: 227 DHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLK 286
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDEN 247
+I E+L ++GA D + + N +DH ++ +L +D H E+
Sbjct: 287 KIAELLCKRGA---STDCGDLVMTARRN-YDHSLVKVLLSHGAK-EDFHPPAED 335
>BC114433-1|AAI14434.1| 741|Homo sapiens ribonuclease L protein.
Length = 741
Score = 57.2 bits (132), Expect = 8e-08
Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 23/198 (11%)
Query: 36 SSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKL---DSGWTPLMHACFHAQDKIV 92
SS ++ V +I + DL+ L+ AN+ + GWTPL +A +++ IV
Sbjct: 16 SSGRRAAVEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIV 75
Query: 93 QYLLEKDADPNLH-SDSVTP-IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTP 150
+ LL ADP L + TP I+AA + S ++ + + +N D YG T
Sbjct: 76 ELLLRHGADPVLRKKNGATPFILAAIAGS-------VKLLKLFLSKGADVNECDFYGFTA 128
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMR-----DQH-----GWTAVFWAVHHNQPEILEMLI 200
M A G+V + L N+ +R DQ G TA+ A E+L++L+
Sbjct: 129 FMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL 188
Query: 201 -EKGARLTEVDKSNRTLL 217
E GA + D R L
Sbjct: 189 DEMGADVNACDNMGRNAL 206
Score = 53.2 bits (122), Expect = 1e-06
Identities = 47/174 (27%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLL-EKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
G T LM A ++++ LL E AD N + + SS D+D + +I L+
Sbjct: 168 GATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSD-VEAITHLLL 226
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP 193
D +N+ G+TPL+ A+ + + Q+LL+ + + I D G TA+ AV
Sbjct: 227 DHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLK 286
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDEN 247
+I E+L ++GA D + + N +DH ++ +L +D H E+
Sbjct: 287 KIAELLCKRGA---STDCGDLVMTARRN-YDHSLVKVLLSHGAK-EDFHPPAED 335
>BC090934-1|AAH90934.1| 652|Homo sapiens RNASEL protein protein.
Length = 652
Score = 57.2 bits (132), Expect = 8e-08
Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 23/198 (11%)
Query: 36 SSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKL---DSGWTPLMHACFHAQDKIV 92
SS ++ V +I + DL+ L+ AN+ + GWTPL +A +++ IV
Sbjct: 16 SSGRRAAVEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIV 75
Query: 93 QYLLEKDADPNLH-SDSVTP-IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTP 150
+ LL ADP L + TP I+AA + S ++ + + +N D YG T
Sbjct: 76 ELLLRHGADPVLRKKNGATPFILAAIAGS-------VKLLKLFLSKGADVNECDFYGFTA 128
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMR-----DQH-----GWTAVFWAVHHNQPEILEMLI 200
M A G+V + L N+ +R DQ G TA+ A E+L++L+
Sbjct: 129 FMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL 188
Query: 201 -EKGARLTEVDKSNRTLL 217
E GA + D R L
Sbjct: 189 DEMGADVNACDNMGRNAL 206
Score = 53.2 bits (122), Expect = 1e-06
Identities = 47/174 (27%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLL-EKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
G T LM A ++++ LL E AD N + + SS D+D + +I L+
Sbjct: 168 GATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSD-VEAITHLLL 226
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP 193
D +N+ G+TPL+ A+ + + Q+LL+ + + I D G TA+ AV
Sbjct: 227 DHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLK 286
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDEN 247
+I E+L ++GA D + + N +DH ++ +L +D H E+
Sbjct: 287 KIAELLCKRGA---STDCGDLVMTARRN-YDHSLVKVLLSHGAK-EDFHPPAED 335
>AL807776-3|CAM13062.1| 871|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 6 protein.
Length = 871
Score = 57.2 bits (132), Expect = 8e-08
Identities = 27/81 (33%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQ-HGWTAVFWAVHHNQPEILEM 198
+N+ + G TPLM A +G++A+ Q L++ +++ +D HGWTA+ A +H EI++
Sbjct: 319 VNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKY 378
Query: 199 LIEKGARLTEVDKSNRTLLEI 219
L+ +GA +T K+ T ++
Sbjct: 379 LLNQGADVTLRAKNGYTAFDL 399
Score = 45.2 bits (102), Expect = 4e-04
Identities = 22/103 (21%), Positives = 50/103 (48%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
++ D G T L A + G + + LL ++ R+ +GW+A+ A + +L
Sbjct: 71 VDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLL 130
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDH 242
++ GA + ++ ++L +A+ H ++++L ++ D H
Sbjct: 131 LDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHH 173
Score = 37.9 bits (84), Expect = 0.055
Identities = 21/72 (29%), Positives = 39/72 (54%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ R +N + YG + LM+A G V+VA LLD ++ +++ G + + A
Sbjct: 97 LLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGH 156
Query: 193 PEILEMLIEKGA 204
++++L+E GA
Sbjct: 157 LGVVKLLLEAGA 168
Score = 37.1 bits (82), Expect = 0.096
Identities = 49/215 (22%), Positives = 85/215 (39%), Gaps = 18/215 (8%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
ALQ A G+ E L+ L+ A++ + GW+ LM A + LL+ AD
Sbjct: 81 ALQFAAAGGH----EPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGAD 136
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCN-LIDRNCI----LNIGDRYGQ----TPLM 152
N + ++ S + +D + L +G + T LM
Sbjct: 137 VNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHPSGEQLGLGGSRDEPLDITALM 196
Query: 153 RAISSGRVAVAQKLLDMQVNIEMRDQH-GWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
AI G AV + L++ + + GW+ + A + + + L+EKGA +
Sbjct: 197 AAIQHGHEAVVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSV 256
Query: 212 SNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDE 246
+T E+A H+ +++ L + KTDE
Sbjct: 257 LEKTAFEVALDCKHRDLVDYLDPLTTVRP--KTDE 289
Score = 37.1 bits (82), Expect = 0.096
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 60 LINNELKNNANI-KLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
L+ ++ +A++ K DS GWT LM A +H +IV+YLL + AD L +
Sbjct: 341 LVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRA 390
Score = 35.9 bits (79), Expect = 0.22
Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 9/118 (7%)
Query: 80 LMHACFHAQDKIVQYLLEKD-ADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
+ HA ++V+ + ++D + NL + D TP+M A ++V L++R+
Sbjct: 296 IFHALKMGNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQL------ALVQLLVERH 349
Query: 138 CILNIGDR-YGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ D +G T LM+A G + + LL+ ++ +R ++G+TA + N P+
Sbjct: 350 ADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTAFDLVMLLNDPD 407
Score = 31.1 bits (67), Expect = 6.3
Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A+ GN + V+++ + + ++ N+ G TPLM A Q +VQ L+E+ AD + D
Sbjct: 299 ALKMGNFQLVKEIADED-PSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVD-KQD 356
Query: 108 SV 109
SV
Sbjct: 357 SV 358
>AL807776-2|CAH69986.2| 584|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 6 protein.
Length = 584
Score = 57.2 bits (132), Expect = 8e-08
Identities = 27/81 (33%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQ-HGWTAVFWAVHHNQPEILEM 198
+N+ + G TPLM A +G++A+ Q L++ +++ +D HGWTA+ A +H EI++
Sbjct: 18 VNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKY 77
Query: 199 LIEKGARLTEVDKSNRTLLEI 219
L+ +GA +T K+ T ++
Sbjct: 78 LLNQGADVTLRAKNGYTAFDL 98
Score = 37.1 bits (82), Expect = 0.096
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 60 LINNELKNNANI-KLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
L+ ++ +A++ K DS GWT LM A +H +IV+YLL + AD L +
Sbjct: 40 LVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRA 89
Score = 34.3 bits (75), Expect = 0.68
Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 11/101 (10%)
Query: 99 DADPN----LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDR-YGQTPLMR 153
D DP+ ++ D TP+M A ++V L++R+ ++ D +G T LM+
Sbjct: 12 DEDPSHVNLVNGDGATPLMLAAVTGQL------ALVQLLVERHADVDKQDSVHGWTALMQ 65
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
A G + + LL+ ++ +R ++G+TA + N P+
Sbjct: 66 ATYHGNKEIVKYLLNQGADVTLRAKNGYTAFDLVMLLNDPD 106
Score = 30.7 bits (66), Expect = 8.3
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV 109
GN + V+++ + + ++ N+ G TPLM A Q +VQ L+E+ AD + DSV
Sbjct: 2 GNFQLVKEIADED-PSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVD-KQDSV 57
>AL353782-4|CAM14169.1| 871|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 6 protein.
Length = 871
Score = 57.2 bits (132), Expect = 8e-08
Identities = 27/81 (33%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQ-HGWTAVFWAVHHNQPEILEM 198
+N+ + G TPLM A +G++A+ Q L++ +++ +D HGWTA+ A +H EI++
Sbjct: 319 VNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKY 378
Query: 199 LIEKGARLTEVDKSNRTLLEI 219
L+ +GA +T K+ T ++
Sbjct: 379 LLNQGADVTLRAKNGYTAFDL 399
Score = 45.2 bits (102), Expect = 4e-04
Identities = 22/103 (21%), Positives = 50/103 (48%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
++ D G T L A + G + + LL ++ R+ +GW+A+ A + +L
Sbjct: 71 VDCSDEAGNTALQFAAAGGHEPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLL 130
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDH 242
++ GA + ++ ++L +A+ H ++++L ++ D H
Sbjct: 131 LDHGADVNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHH 173
Score = 37.9 bits (84), Expect = 0.055
Identities = 21/72 (29%), Positives = 39/72 (54%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ R +N + YG + LM+A G V+VA LLD ++ +++ G + + A
Sbjct: 97 LLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGADVNAQNRLGASVLTVASRGGH 156
Query: 193 PEILEMLIEKGA 204
++++L+E GA
Sbjct: 157 LGVVKLLLEAGA 168
Score = 37.1 bits (82), Expect = 0.096
Identities = 49/215 (22%), Positives = 85/215 (39%), Gaps = 18/215 (8%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDS--GWTPLMHACFHAQDKIVQYLLEKDAD 101
ALQ A G+ E L+ L+ A++ + GW+ LM A + LL+ AD
Sbjct: 81 ALQFAAAGGH----EPLVRFLLRRGASVNSRNHYGWSALMQAARFGHVSVAHLLLDHGAD 136
Query: 102 PNLHSDSVTPIMAACSNSSADNDTIYSIVCN-LIDRNCI----LNIGDRYGQ----TPLM 152
N + ++ S + +D + L +G + T LM
Sbjct: 137 VNAQNRLGASVLTVASRGGHLGVVKLLLEAGAFVDHHHPSGEQLGLGGSRDEPLDITALM 196
Query: 153 RAISSGRVAVAQKLLDMQVNIEMRDQH-GWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
AI G AV + L++ + + GW+ + A + + + L+EKGA +
Sbjct: 197 AAIQHGHEAVVRLLMEWGADPNHAARTVGWSPLMLAALTGRLGVAQQLVEKGANPDHLSV 256
Query: 212 SNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDE 246
+T E+A H+ +++ L + KTDE
Sbjct: 257 LEKTAFEVALDCKHRDLVDYLDPLTTVRP--KTDE 289
Score = 37.1 bits (82), Expect = 0.096
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 60 LINNELKNNANI-KLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
L+ ++ +A++ K DS GWT LM A +H +IV+YLL + AD L +
Sbjct: 341 LVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRA 390
Score = 35.9 bits (79), Expect = 0.22
Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 9/118 (7%)
Query: 80 LMHACFHAQDKIVQYLLEKD-ADPNL-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
+ HA ++V+ + ++D + NL + D TP+M A ++V L++R+
Sbjct: 296 IFHALKMGNFQLVKEIADEDPSHVNLVNGDGATPLMLAAVTGQL------ALVQLLVERH 349
Query: 138 CILNIGDR-YGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ D +G T LM+A G + + LL+ ++ +R ++G+TA + N P+
Sbjct: 350 ADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRAKNGYTAFDLVMLLNDPD 407
Score = 31.1 bits (67), Expect = 6.3
Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 2/62 (3%)
Query: 48 AIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD 107
A+ GN + V+++ + + ++ N+ G TPLM A Q +VQ L+E+ AD + D
Sbjct: 299 ALKMGNFQLVKEIADED-PSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVD-KQD 356
Query: 108 SV 109
SV
Sbjct: 357 SV 358
>AL353782-3|CAH71296.2| 584|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 6 protein.
Length = 584
Score = 57.2 bits (132), Expect = 8e-08
Identities = 27/81 (33%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQ-HGWTAVFWAVHHNQPEILEM 198
+N+ + G TPLM A +G++A+ Q L++ +++ +D HGWTA+ A +H EI++
Sbjct: 18 VNLVNGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKY 77
Query: 199 LIEKGARLTEVDKSNRTLLEI 219
L+ +GA +T K+ T ++
Sbjct: 78 LLNQGADVTLRAKNGYTAFDL 98
Score = 37.1 bits (82), Expect = 0.096
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 60 LINNELKNNANI-KLDS--GWTPLMHACFHAQDKIVQYLLEKDADPNLHS 106
L+ ++ +A++ K DS GWT LM A +H +IV+YLL + AD L +
Sbjct: 40 LVQLLVERHADVDKQDSVHGWTALMQATYHGNKEIVKYLLNQGADVTLRA 89
Score = 34.3 bits (75), Expect = 0.68
Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 11/101 (10%)
Query: 99 DADPN----LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDR-YGQTPLMR 153
D DP+ ++ D TP+M A ++V L++R+ ++ D +G T LM+
Sbjct: 12 DEDPSHVNLVNGDGATPLMLAAVTGQL------ALVQLLVERHADVDKQDSVHGWTALMQ 65
Query: 154 AISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
A G + + LL+ ++ +R ++G+TA + N P+
Sbjct: 66 ATYHGNKEIVKYLLNQGADVTLRAKNGYTAFDLVMLLNDPD 106
Score = 30.7 bits (66), Expect = 8.3
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV 109
GN + V+++ + + ++ N+ G TPLM A Q +VQ L+E+ AD + DSV
Sbjct: 2 GNFQLVKEIADED-PSHVNLVNGDGATPLMLAAVTGQLALVQLLVERHADVD-KQDSV 57
>AL138776-1|CAH71322.1| 741|Homo sapiens ribonuclease L
(2',5'-oligoisoadenylate synthetase-dependent) protein.
Length = 741
Score = 57.2 bits (132), Expect = 8e-08
Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 23/198 (11%)
Query: 36 SSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKL---DSGWTPLMHACFHAQDKIV 92
SS ++ V +I + DL+ L+ AN+ + GWTPL +A +++ IV
Sbjct: 16 SSGRRAAVEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIV 75
Query: 93 QYLLEKDADPNLH-SDSVTP-IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTP 150
+ LL ADP L + TP I+AA + S ++ + + +N D YG T
Sbjct: 76 ELLLRHGADPVLRKKNGATPFILAAIAGS-------VKLLKLFLSKGADVNECDFYGFTA 128
Query: 151 LMRAISSGRVAVAQKLLDMQVNIEMR-----DQH-----GWTAVFWAVHHNQPEILEMLI 200
M A G+V + L N+ +R DQ G TA+ A E+L++L+
Sbjct: 129 FMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL 188
Query: 201 -EKGARLTEVDKSNRTLL 217
E GA + D R L
Sbjct: 189 DEMGADVNACDNMGRNAL 206
Score = 53.2 bits (122), Expect = 1e-06
Identities = 47/174 (27%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLL-EKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
G T LM A ++++ LL E AD N + + SS D+D + +I L+
Sbjct: 168 GATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSD-VEAITHLLL 226
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP 193
D +N+ G+TPL+ A+ + + Q+LL+ + + I D G TA+ AV
Sbjct: 227 DHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLK 286
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDEN 247
+I E+L ++GA D + + N +DH ++ +L +D H E+
Sbjct: 287 KIAELLCKRGA---STDCGDLVMTARRN-YDHSLVKVLLSHGAK-EDFHPPAED 335
>AL031177-4|CAI43134.1| 193|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 193
Score = 57.2 bits (132), Expect = 8e-08
Identities = 43/171 (25%), Positives = 85/171 (49%), Gaps = 8/171 (4%)
Query: 51 NGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSV 109
+G ++++++ I + K+ A +GW+PL A +D+IV+ LL K A N ++ +
Sbjct: 16 SGKLEELKESILAD-KSLATRTDQAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGC 74
Query: 110 TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDM 169
TP+ A S + + I L++ + D Y T + RA + G + + LL
Sbjct: 75 TPLHYAASKNR------HEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYY 128
Query: 170 QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ + ++D G T + A + E ++L+ +GA + +K +T L++A
Sbjct: 129 KASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 179
Score = 46.4 bits (105), Expect = 2e-04
Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D+ G +PL A S+GR + + LL + +Q+G T + +A N+ EI ML+E G
Sbjct: 37 DQAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 96
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEIL---KKSLNLDD 240
A D T + A + +I IL K S N+ D
Sbjct: 97 ANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 136
>AC007874-1|AAF19231.1| 131|Homo sapiens WUGSC:H_DJ1035O02.1
protein.
Length = 131
Score = 57.2 bits (132), Expect = 8e-08
Identities = 36/134 (26%), Positives = 73/134 (54%), Gaps = 7/134 (5%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLH-SDSVTPIMAACSNSSADNDTIYSIVCNLIDR 136
TPL AC + +V +L+E+ N+ S++ +P++ A + D TI L++
Sbjct: 1 TPLHLACANGHTDVVLFLIEQQCKINVRDSENKSPLIKAVQCQNEDCATI------LLNF 54
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEIL 196
++ D T L A+ +++ +KLL+ + ++E +++ G+T + AV +N P+++
Sbjct: 55 GADPDLRDIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNPKMV 114
Query: 197 EMLIEKGARLTEVD 210
+ L+EKGA + D
Sbjct: 115 KFLLEKGADVNASD 128
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 6/123 (4%)
Query: 110 TPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDM 169
TP+ AC+N D +V LI++ C +N+ D ++PL++A+ A LL+
Sbjct: 1 TPLHLACANGHTD------VVLFLIEQQCKINVRDSENKSPLIKAVQCQNEDCATILLNF 54
Query: 170 QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVII 229
+ ++RD T + +AV ++E L+E A L +K T L +A +++ ++
Sbjct: 55 GADPDLRDIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNPKMV 114
Query: 230 EIL 232
+ L
Sbjct: 115 KFL 117
Score = 36.3 bits (80), Expect = 0.17
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 40 KVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKD 99
+ L A+ ++ VE L+ E A K G+TPL+ A + K+V++LLEK
Sbjct: 64 RYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNK--DGYTPLLVAVINNNPKMVKFLLEKG 121
Query: 100 ADPN 103
AD N
Sbjct: 122 ADVN 125
>AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein
protein.
Length = 968
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/192 (27%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A G + ++ L+N + N+ G +PLM A + V+ LL+ +D N
Sbjct: 653 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINA 712
Query: 104 -LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++ T + AC A+ +V L+DR + + G TPLM A S G V
Sbjct: 713 QIETNRNTALTLACFQGRAE------VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 766
Query: 163 AQKLLDM--QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ LLD VN TA+ A + E+LI +GA + +K T L +A
Sbjct: 767 GRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLA 826
Query: 221 NCHDHQVIIEIL 232
+ H ++++L
Sbjct: 827 SNGGHFDVVQLL 838
Score = 51.6 bits (118), Expect = 4e-06
Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 51 NGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-- 108
+G ++V DL+ N + + S +TPL A I++ LL A+ N + S
Sbjct: 625 SGGRQEVVDLLLARGANKEHRNV-SDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKL 683
Query: 109 -VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIG-DRYGQTPLMRAISSGRVAVAQKL 166
++P+M A N V L+D +N + T L A GR V L
Sbjct: 684 GISPLMLAAMNGHVP------AVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 737
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT--EVDKSNRTLLEIANCHD 224
LD + N+E R + G T + A E+ +L++KGA + V S T L IA
Sbjct: 738 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG 797
Query: 225 HQVIIEIL 232
H E+L
Sbjct: 798 HYKFCELL 805
Score = 48.0 bits (109), Expect = 5e-05
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 7/135 (5%)
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
D D + S+ T + AC+ + +V LI R+ + D+ G TPL+ A ++G
Sbjct: 540 DIDAHTESNHDTALTLACAGGHEE------LVSVLIARDAKIEHRDKKGFTPLILAATAG 593
Query: 159 RVAVAQKLLDMQVNIEMRDQHGW-TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V V + LLD +IE + + T + A + E++++L+ +GA + S+ T L
Sbjct: 594 HVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPL 653
Query: 218 EIANCHDHQVIIEIL 232
+A + II+IL
Sbjct: 654 SLAASGGYVNIIKIL 668
Score = 45.2 bits (102), Expect = 4e-04
Identities = 52/210 (24%), Positives = 94/210 (44%), Gaps = 16/210 (7%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
+ AL A G+ + V LI + K K G+TPL+ A +V+ LL+K D
Sbjct: 550 DTALTLACAGGHEELVSVLIARDAKIEHRDK--KGFTPLILAATAGHVGVVEILLDKGGD 607
Query: 102 PNLHSDSV--TPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
S+ TP+ ACS + D + + N R N+ D TPL A S G
Sbjct: 608 IEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHR----NVSD---YTPLSLAASGG 660
Query: 159 RVAVAQKLLD--MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRT 215
V + + LL+ ++N + G + + A + +++L++ G+ + +++ + T
Sbjct: 661 YVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNT 720
Query: 216 LLEIANCHDH-QVIIEILKKSLNLDDDHKT 244
L +A +V+ +L + N++ KT
Sbjct: 721 ALTLACFQGRAEVVSLLLDRKANVEHRAKT 750
Score = 41.1 bits (92), Expect = 0.006
Identities = 52/184 (28%), Positives = 76/184 (41%), Gaps = 20/184 (10%)
Query: 66 KNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMA---ACSNSSAD 122
K A+I+L TPLM A ++V+YLL A N+H+ + T A AC N D
Sbjct: 1 KAGADIELGCS-TPLMEASQEGHLELVKYLLASGA--NVHATTATGDTALTYACENGHTD 57
Query: 123 -NDTIYSIVCNLI---DRNCILNIGD---------RYGQTPLMRAISSGRVAVAQKLLDM 169
D + +L D IL D G+TPLM+A +G + Q L+
Sbjct: 58 VADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISK 117
Query: 170 QVNIEMRD-QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVI 228
N+ + T V A ++E+L+ GA T K T+L A H +
Sbjct: 118 GANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNV 177
Query: 229 IEIL 232
+ L
Sbjct: 178 VSYL 181
>AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens
cDNA FLJ25613 fis, clone STM01546. ).
Length = 353
Score = 56.8 bits (131), Expect = 1e-07
Identities = 47/184 (25%), Positives = 81/184 (44%), Gaps = 10/184 (5%)
Query: 61 INNELKNNANIKL-DSGW-TPLMHACFHAQDKIVQYLLEKDADPNLHSDS-VTPIMAACS 117
I N + AN+ D+ W PL A +K++ LL AD N TP+ A +
Sbjct: 75 IGNYIPTGANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAA 134
Query: 118 NSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRD 177
N + + L+ LN+ DR G++ L A+ SG + LL+ ++ + D
Sbjct: 135 NRATK---CAEALAPLLSS---LNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCD 188
Query: 178 QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDH-QVIIEILKKSL 236
+ + WA E+L++L+ +GA L D+ LL A +V+ +L+
Sbjct: 189 KKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGA 248
Query: 237 NLDD 240
+D+
Sbjct: 249 EIDE 252
Score = 37.1 bits (82), Expect = 0.096
Identities = 39/162 (24%), Positives = 71/162 (43%), Gaps = 8/162 (4%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A+ +G+++ V L+N N K + PL A F ++++ L+ + AD
Sbjct: 161 ALHHAVHSGHLETVNLLLNKGASLNVCDKKER--QPLHWAAFLGHLEVLKLLVARGADLG 218
Query: 104 LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
++ + S +V L+ ++ + +G T L A G+ AVA
Sbjct: 219 CKDRKGYGLLHTAAASGQ-----IEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDAVA 273
Query: 164 QKLLDMQVNIEMRDQHGWTAV-FWAVHHNQPEILEMLIEKGA 204
+L++ N+ + G+T + AV N LE+L+ GA
Sbjct: 274 IELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGA 315
>AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens
cDNA FLJ20288 fis, clone HEP04414. ).
Length = 686
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/192 (27%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A G + ++ L+N + N+ G +PLM A + V+ LL+ +D N
Sbjct: 370 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINA 429
Query: 104 -LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++ T + AC A+ +V L+DR + + G TPLM A S G V
Sbjct: 430 QIETNRNTALTLACFQGRAE------VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 483
Query: 163 AQKLLDM--QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ LLD VN TA+ A + E+LI +GA + +K T L +A
Sbjct: 484 GRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLA 543
Query: 221 NCHDHQVIIEIL 232
+ H ++++L
Sbjct: 544 SNGGHFDVVQLL 555
Score = 51.6 bits (118), Expect = 4e-06
Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 51 NGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-- 108
+G ++V DL+ N + + S +TPL A I++ LL A+ N + S
Sbjct: 342 SGGRQEVVDLLLARGANKEHRNV-SDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKL 400
Query: 109 -VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIG-DRYGQTPLMRAISSGRVAVAQKL 166
++P+M A N V L+D +N + T L A GR V L
Sbjct: 401 GISPLMLAAMNGHVP------AVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 454
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT--EVDKSNRTLLEIANCHD 224
LD + N+E R + G T + A E+ +L++KGA + V S T L IA
Sbjct: 455 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG 514
Query: 225 HQVIIEIL 232
H E+L
Sbjct: 515 HYKFCELL 522
Score = 48.4 bits (110), Expect = 4e-05
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 7/135 (5%)
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
D D + S+ T + AC+ + +V LI R+ + D+ G TPL+ A ++G
Sbjct: 257 DVDAHTESNHDTALTLACAGGHEE------LVSVLIARDAKIEHRDKKGFTPLILAATAG 310
Query: 159 RVAVAQKLLDMQVNIEMRDQHGW-TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V V + LLD +IE + + T + A + E++++L+ +GA + S+ T L
Sbjct: 311 HVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPL 370
Query: 218 EIANCHDHQVIIEIL 232
+A + II+IL
Sbjct: 371 SLAASGGYVNIIKIL 385
Score = 45.2 bits (102), Expect = 4e-04
Identities = 52/210 (24%), Positives = 94/210 (44%), Gaps = 16/210 (7%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
+ AL A G+ + V LI + K K G+TPL+ A +V+ LL+K D
Sbjct: 267 DTALTLACAGGHEELVSVLIARDAKIEHRDK--KGFTPLILAATAGHVGVVEILLDKGGD 324
Query: 102 PNLHSDSV--TPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
S+ TP+ ACS + D + + N R N+ D TPL A S G
Sbjct: 325 IEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHR----NVSD---YTPLSLAASGG 377
Query: 159 RVAVAQKLLD--MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRT 215
V + + LL+ ++N + G + + A + +++L++ G+ + +++ + T
Sbjct: 378 YVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNT 437
Query: 216 LLEIANCHDH-QVIIEILKKSLNLDDDHKT 244
L +A +V+ +L + N++ KT
Sbjct: 438 ALTLACFQGRAEVVSLLLDRKANVEHRAKT 467
Score = 33.9 bits (74), Expect = 0.89
Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 1/87 (1%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRD-QHGWTAVFWAVHHNQPEILEMLIEKGAR 205
G+TPLM+A +G + Q L+ N+ + T V A ++E+L+ GA
Sbjct: 81 GRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGAD 140
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEIL 232
T K T+L A H ++ L
Sbjct: 141 PTHRLKDGSTMLIEAAKGGHTNVVSYL 167
>AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein
protein.
Length = 532
Score = 56.8 bits (131), Expect = 1e-07
Identities = 52/192 (27%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A G + ++ L+N + N+ G +PLM A + V+ LL+ +D N
Sbjct: 236 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINA 295
Query: 104 -LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++ T + AC A+ +V L+DR + + G TPLM A S G V
Sbjct: 296 QIETNRNTALTLACFQGRAE------VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 349
Query: 163 AQKLLDM--QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ LLD VN TA+ A + E+LI +GA + +K T L +A
Sbjct: 350 GRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLA 409
Query: 221 NCHDHQVIIEIL 232
+ H ++++L
Sbjct: 410 SNGGHFDVVQLL 421
Score = 51.6 bits (118), Expect = 4e-06
Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 13/188 (6%)
Query: 51 NGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDS-- 108
+G ++V DL+ N + + S +TPL A I++ LL A+ N + S
Sbjct: 208 SGGRQEVVDLLLARGANKEHRNV-SDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKL 266
Query: 109 -VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIG-DRYGQTPLMRAISSGRVAVAQKL 166
++P+M A N V L+D +N + T L A GR V L
Sbjct: 267 GISPLMLAAMNGHVP------AVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLL 320
Query: 167 LDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT--EVDKSNRTLLEIANCHD 224
LD + N+E R + G T + A E+ +L++KGA + V S T L IA
Sbjct: 321 LDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDTALTIAADKG 380
Query: 225 HQVIIEIL 232
H E+L
Sbjct: 381 HYKFCELL 388
Score = 48.0 bits (109), Expect = 5e-05
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 7/135 (5%)
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
D D + S+ T + AC+ + +V LI R+ + D+ G TPL+ A ++G
Sbjct: 123 DIDAHTESNHDTALTLACAGGHEE------LVSVLIARDAKIEHRDKKGFTPLILAATAG 176
Query: 159 RVAVAQKLLDMQVNIEMRDQHGW-TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V V + LLD +IE + + T + A + E++++L+ +GA + S+ T L
Sbjct: 177 HVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPL 236
Query: 218 EIANCHDHQVIIEIL 232
+A + II+IL
Sbjct: 237 SLAASGGYVNIIKIL 251
Score = 45.2 bits (102), Expect = 4e-04
Identities = 52/210 (24%), Positives = 94/210 (44%), Gaps = 16/210 (7%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
+ AL A G+ + V LI + K K G+TPL+ A +V+ LL+K D
Sbjct: 133 DTALTLACAGGHEELVSVLIARDAKIEHRDK--KGFTPLILAATAGHVGVVEILLDKGGD 190
Query: 102 PNLHSDSV--TPIMAACSNSSAD-NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
S+ TP+ ACS + D + + N R N+ D TPL A S G
Sbjct: 191 IEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHR----NVSD---YTPLSLAASGG 243
Query: 159 RVAVAQKLLD--MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRT 215
V + + LL+ ++N + G + + A + +++L++ G+ + +++ + T
Sbjct: 244 YVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNT 303
Query: 216 LLEIANCHDH-QVIIEILKKSLNLDDDHKT 244
L +A +V+ +L + N++ KT
Sbjct: 304 ALTLACFQGRAEVVSLLLDRKANVEHRAKT 333
>BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein.
Length = 420
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/181 (22%), Positives = 89/181 (49%), Gaps = 5/181 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
G+++ ++ L+N+ K + K G T L A ++ +++E D L D V
Sbjct: 8 GHLRILQILVNSGAKIHCESK--DGLTLLHCAAQKGHVPVLAFIMEDLEDVAL--DHVDK 63
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ + +A++ + ++ L+ C N+ D+ G T L A G +AV Q+L+D+ +
Sbjct: 64 LGRTAFHRAAEHGQLDALDF-LVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGL 122
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
++E ++ G TA+ A + P+ +++L+ G+ + + + N + L A + + +
Sbjct: 123 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 182
Query: 232 L 232
L
Sbjct: 183 L 183
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/74 (32%), Positives = 40/74 (54%)
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
++V LI+ + +N D QTPL A +A LL V++ +RD+ G TA+ A
Sbjct: 211 ALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDEQGKTALAVA 270
Query: 188 VHHNQPEILEMLIE 201
V N +++M+I+
Sbjct: 271 VRSNHVSLVDMIIK 284
Score = 33.1 bits (72), Expect = 1.6
Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 69 ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIY 127
AN+ G +PL A H +V+ L+ D+D N + + TP+ A ++ D
Sbjct: 190 ANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD----- 244
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLL 167
I L+ LN+ D G+T L A+ S V++ ++
Sbjct: 245 -IADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMII 283
>BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/181 (22%), Positives = 89/181 (49%), Gaps = 5/181 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
G+++ ++ L+N+ K + K G T L A ++ +++E D L D V
Sbjct: 11 GHLRILQILVNSGAKIHCESK--DGLTLLHCAAQKGHVPVLAFIMEDLEDVAL--DHVDK 66
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ + +A++ + ++ L+ C N+ D+ G T L A G +AV Q+L+D+ +
Sbjct: 67 LGRTAFHRAAEHGQLDALDF-LVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGL 125
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
++E ++ G TA+ A + P+ +++L+ G+ + + + N + L A + + +
Sbjct: 126 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 185
Query: 232 L 232
L
Sbjct: 186 L 186
Score = 46.8 bits (106), Expect = 1e-04
Identities = 50/211 (23%), Positives = 90/211 (42%), Gaps = 12/211 (5%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A G+M ++ L++ L + + G T L A + VQ LL
Sbjct: 99 KEGNTALHLAAGRGHMAVLQRLVDIGL--DLEEQNAEGLTALHSAAGGSHPDCVQLLLRA 156
Query: 99 DADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
+ N L +++ + A + S D + LI N+ D G +PL A+
Sbjct: 157 GSTVNALTQKNLSCLHYAALSGSEDVSRV------LIHAGGCANVVDHQGASPLHLAVRH 210
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
A+ + L++ ++ D T + A H +I +ML+ G L DK +T L
Sbjct: 211 NFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKQGKTAL 270
Query: 218 EIANCHDHQVIIEILKKS---LNLDDDHKTD 245
+A +H +++++ K+ + DH +D
Sbjct: 271 AVAVRSNHVSLVDMIIKADRFYRWEKDHPSD 301
>BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/181 (22%), Positives = 89/181 (49%), Gaps = 5/181 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
G+++ ++ L+N+ K + K G T L A ++ +++E D L D V
Sbjct: 11 GHLRILQILVNSGAKIHCESK--DGLTLLHCAAQKGHVPVLAFIMEDLEDVAL--DHVDK 66
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ + +A++ + ++ L+ C N+ D+ G T L A G +AV Q+L+D+ +
Sbjct: 67 LGRTAFHRAAEHGQLDALDF-LVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGL 125
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
++E ++ G TA+ A + P+ +++L+ G+ + + + N + L A + + +
Sbjct: 126 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 185
Query: 232 L 232
L
Sbjct: 186 L 186
Score = 39.9 bits (89), Expect = 0.014
Identities = 24/74 (32%), Positives = 40/74 (54%)
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
++V LI+ + +N D QTPL A +A LL V++ +RD+ G TA+ A
Sbjct: 214 ALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDEQGKTALAVA 273
Query: 188 VHHNQPEILEMLIE 201
V N +++M+I+
Sbjct: 274 VRSNHVSLVDMIIK 287
Score = 33.1 bits (72), Expect = 1.6
Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 69 ANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIY 127
AN+ G +PL A H +V+ L+ D+D N + + TP+ A ++ D
Sbjct: 193 ANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQD----- 247
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLL 167
I L+ LN+ D G+T L A+ S V++ ++
Sbjct: 248 -IADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMII 286
>BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein.
Length = 399
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/181 (22%), Positives = 89/181 (49%), Gaps = 5/181 (2%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTP 111
G+++ ++ L+N+ K + K G T L A ++ +++E D L D V
Sbjct: 11 GHLRILQILVNSGAKIHCESK--DGLTLLHCAAQKGHVPVLAFIMEDLEDVAL--DHVDK 66
Query: 112 IMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQV 171
+ + +A++ + ++ L+ C N+ D+ G T L A G +AV Q+L+D+ +
Sbjct: 67 LGRTAFHRAAEHGQLDALDF-LVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGL 125
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEI 231
++E ++ G TA+ A + P+ +++L+ G+ + + + N + L A + + +
Sbjct: 126 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 185
Query: 232 L 232
L
Sbjct: 186 L 186
Score = 35.1 bits (77), Expect = 0.39
Identities = 42/176 (23%), Positives = 72/176 (40%), Gaps = 9/176 (5%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
K+ AL A G+M ++ L++ L + + G T L A + VQ LL
Sbjct: 99 KEGNTALHLAAGRGHMAVLQRLVDIGL--DLEEQNAEGLTALHSAAGGSHPDCVQLLLRA 156
Query: 99 DADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISS 157
+ N L +++ + A + S D + LI N+ D G +PL A+
Sbjct: 157 GSTVNALTQKNLSCLHYAALSGSEDVSRV------LIHAGGCANVVDHQGASPLHLAVRH 210
Query: 158 GRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSN 213
A+ + L++ ++ D T + A H +I +ML+ G L DK +
Sbjct: 211 NFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKDH 266
>BC071771-1|AAH71771.1| 239|Homo sapiens KIAA1641 protein protein.
Length = 239
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/108 (30%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ R C LN+ DR +TPL++A+ + A A LL + + D G TA+ +AV++
Sbjct: 72 LVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGADPNITDVFGRTALHYAVYNED 131
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIE-ILKKSLNLD 239
++E L+ G + E K+ L +A ++E +LKK N++
Sbjct: 132 TSMIEKLLSHGTNIEECSKNEYQPLLLAVSRRKVKMVEFLLKKKANVN 179
Score = 52.8 bits (121), Expect = 2e-06
Identities = 44/196 (22%), Positives = 94/196 (47%), Gaps = 10/196 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
+ A++ GN++ ++ L+ N + + T L AC Q ++V L+ + + NL
Sbjct: 24 IHRAVLRGNLEKLKYLLLTYYDANKRDRKER--TALHLACATGQPEMVHLLVSRRCELNL 81
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ TP++ A T+ L+ NI D +G+T L A+ + ++
Sbjct: 82 CDREDRTPLIKAVQLRQEACATL------LLQNGADPNITDVFGRTALHYAVYNEDTSMI 135
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA-NC 222
+KLL NIE ++ + + AV + +++E L++K A + +D R+ L +A
Sbjct: 136 EKLLSHGTNIEECSKNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTL 195
Query: 223 HDHQVIIEILKKSLNL 238
+ ++I +L+ ++++
Sbjct: 196 GEKDIVILLLQHNIDV 211
Score = 43.2 bits (97), Expect = 0.001
Identities = 42/190 (22%), Positives = 83/190 (43%), Gaps = 7/190 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K AL A G + V L++ + N + D TPL+ A Q+ LL+
Sbjct: 51 RKERTALHLACATGQPEMVHLLVSRRCELNLCDREDR--TPLIKAVQLRQEACATLLLQN 108
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
ADPN +T + + A + S++ L+ + + PL+ A+S
Sbjct: 109 GADPN-----ITDVFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKNEYQPLLLAVSRR 163
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+V + + LL + N+ D G +A+ AV + +I+ +L++ + D + +
Sbjct: 164 KVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRDVYGKLAED 223
Query: 219 IANCHDHQVI 228
A+ +++V+
Sbjct: 224 YASEAENRVV 233
>BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein.
Length = 751
Score = 56.4 bits (130), Expect = 1e-07
Identities = 43/176 (24%), Positives = 83/176 (47%), Gaps = 11/176 (6%)
Query: 65 LKNNANIKLDSGW---TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSS 120
L+N A I S + L AC+ ++V++LLE AD +D + T +M AC +
Sbjct: 387 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGH 446
Query: 121 ADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG 180
+ + L+D +N+ ++PL A G V +A L++ ++E + G
Sbjct: 447 VE------VARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEG 500
Query: 181 WTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+T + A E++ +L+ +GA + + +++ T L +A C + + L K+
Sbjct: 501 YTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKA 556
Score = 50.8 bits (116), Expect = 7e-06
Identities = 47/153 (30%), Positives = 72/153 (47%), Gaps = 11/153 (7%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDR 136
TPLM A KIV+ LL AD N S + T + AC+ D +V L++
Sbjct: 303 TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVD------VVKVLLES 356
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR-DQHGWTAVFWAVHHNQPEI 195
+ + G TPLM A S+G V VA+ LL+ I ++ +A+ A + E+
Sbjct: 357 GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEM 416
Query: 196 LEMLIEKGA-RLTEVDKSNRTLLEIANCHDHQV 227
+ L+E GA + + D+ + L+E C D V
Sbjct: 417 VRFLLEAGADQEHKTDEMHTALMEA--CMDGHV 447
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 10/178 (5%)
Query: 59 DLINNELKNNANIK--LDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMA 114
D++ L++ A+I+ ++G TPLM A ++ + LLE A N HS+ + +
Sbjct: 348 DVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTL 407
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
AC + +V L++ T LM A G V VA+ LLD +
Sbjct: 408 ACYKGHLE------MVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 461
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
M + + A E+ +LIE+GA L EV+ T L A H+ ++ +L
Sbjct: 462 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 519
Score = 49.6 bits (113), Expect = 2e-05
Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 18/202 (8%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A G + +V D + +K A+I+L TPLM A ++V+YLL A
Sbjct: 535 ETALTLACCGGFL-EVADFL---IKAGADIELGCS-TPLMEAAQEGHLELVKYLLAAGA- 588
Query: 102 PNLHSDSVTPIMA---ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
N+H+ + T A AC N D + L+ L G+TPLM+A +G
Sbjct: 589 -NVHATTATGDTALTYACENGHTDVADV------LLQAGADLEHESEGGRTPLMKAARAG 641
Query: 159 RVAVAQKLLDMQVNIEMRD-QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-L 216
V Q L+ N+ + T + A ++E+L+ GA T K T L
Sbjct: 642 HVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 701
Query: 217 LEIANCHDHQVIIEILKKSLNL 238
+E A V+ +L NL
Sbjct: 702 IEAAKGGHTSVVCYLLDYPNNL 723
Score = 46.8 bits (106), Expect = 1e-04
Identities = 45/190 (23%), Positives = 86/190 (45%), Gaps = 10/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A G++K V+ L+ + K + N + +G T L +AC +V+ LLE A
Sbjct: 305 LMAAANGGHVKIVKLLLAH--KADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 362
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAV 162
H+++ TP+M A S + + L++ +N + + ++ L A G + +
Sbjct: 363 HNENGHTPLMEAGSAGHVE------VARLLLENGAGINTHSNEFKESALTLACYKGHLEM 416
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LL+ + E + TA+ A E+ +L++ GA++ S + L +A C
Sbjct: 417 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 476
Query: 223 HDHQVIIEIL 232
H + +L
Sbjct: 477 GGHVELAALL 486
Score = 35.5 bits (78), Expect = 0.29
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG-WTAVFWAVHHNQPEILEMLIEKGAR 205
G++ L A S+G +AQ LL M N+E R G T + A + +I+++L+ A
Sbjct: 267 GESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKAD 326
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSY 249
+ + T L A + ++++L +S +DH +EN +
Sbjct: 327 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDH--NENGH 368
>BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein.
Length = 830
Score = 56.4 bits (130), Expect = 1e-07
Identities = 43/176 (24%), Positives = 83/176 (47%), Gaps = 11/176 (6%)
Query: 65 LKNNANIKLDSGW---TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSS 120
L+N A I S + L AC+ ++V++LLE AD +D + T +M AC +
Sbjct: 207 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGH 266
Query: 121 ADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG 180
+ + L+D +N+ ++PL A G V +A L++ ++E + G
Sbjct: 267 VE------VARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEG 320
Query: 181 WTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+T + A E++ +L+ +GA + + +++ T L +A C + + L K+
Sbjct: 321 YTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKA 376
Score = 50.8 bits (116), Expect = 7e-06
Identities = 47/153 (30%), Positives = 72/153 (47%), Gaps = 11/153 (7%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDR 136
TPLM A KIV+ LL AD N S + T + AC+ D +V L++
Sbjct: 123 TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVD------VVKVLLES 176
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR-DQHGWTAVFWAVHHNQPEI 195
+ + G TPLM A S+G V VA+ LL+ I ++ +A+ A + E+
Sbjct: 177 GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEM 236
Query: 196 LEMLIEKGA-RLTEVDKSNRTLLEIANCHDHQV 227
+ L+E GA + + D+ + L+E C D V
Sbjct: 237 VRFLLEAGADQEHKTDEMHTALMEA--CMDGHV 267
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 10/178 (5%)
Query: 59 DLINNELKNNANIK--LDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMA 114
D++ L++ A+I+ ++G TPLM A ++ + LLE A N HS+ + +
Sbjct: 168 DVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTL 227
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
AC + +V L++ T LM A G V VA+ LLD +
Sbjct: 228 ACYKGHLE------MVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 281
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
M + + A E+ +LIE+GA L EV+ T L A H+ ++ +L
Sbjct: 282 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 339
Score = 49.6 bits (113), Expect = 2e-05
Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 18/202 (8%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A G + +V D + +K A+I+L TPLM A ++V+YLL A
Sbjct: 355 ETALTLACCGGFL-EVADFL---IKAGADIELGCS-TPLMEAAQEGHLELVKYLLAAGA- 408
Query: 102 PNLHSDSVTPIMA---ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
N+H+ + T A AC N D + L+ L G+TPLM+A +G
Sbjct: 409 -NVHATTATGDTALTYACENGHTDVADV------LLQAGADLEHESEGGRTPLMKAARAG 461
Query: 159 RVAVAQKLLDMQVNIEMRD-QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-L 216
V Q L+ N+ + T + A ++E+L+ GA T K T L
Sbjct: 462 HVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 521
Query: 217 LEIANCHDHQVIIEILKKSLNL 238
+E A V+ +L NL
Sbjct: 522 IEAAKGGHTSVVCYLLDYPNNL 543
Score = 46.8 bits (106), Expect = 1e-04
Identities = 45/190 (23%), Positives = 86/190 (45%), Gaps = 10/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A G++K V+ L+ + K + N + +G T L +AC +V+ LLE A
Sbjct: 125 LMAAANGGHVKIVKLLLAH--KADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 182
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAV 162
H+++ TP+M A S + + L++ +N + + ++ L A G + +
Sbjct: 183 HNENGHTPLMEAGSAGHVE------VARLLLENGAGINTHSNEFKESALTLACYKGHLEM 236
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LL+ + E + TA+ A E+ +L++ GA++ S + L +A C
Sbjct: 237 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 296
Query: 223 HDHQVIIEIL 232
H + +L
Sbjct: 297 GGHVELAALL 306
Score = 35.5 bits (78), Expect = 0.29
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG-WTAVFWAVHHNQPEILEMLIEKGAR 205
G++ L A S+G +AQ LL M N+E R G T + A + +I+++L+ A
Sbjct: 87 GESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKAD 146
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSY 249
+ + T L A + ++++L +S +DH +EN +
Sbjct: 147 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDH--NENGH 188
>BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein.
Length = 1500
Score = 56.4 bits (130), Expect = 1e-07
Identities = 43/176 (24%), Positives = 83/176 (47%), Gaps = 11/176 (6%)
Query: 65 LKNNANIKLDSGW---TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSS 120
L+N A I S + L AC+ ++V++LLE AD +D + T +M AC +
Sbjct: 387 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGH 446
Query: 121 ADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG 180
+ + L+D +N+ ++PL A G V +A L++ ++E + G
Sbjct: 447 VE------VARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEG 500
Query: 181 WTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+T + A E++ +L+ +GA + + +++ T L +A C + + L K+
Sbjct: 501 YTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKA 556
Score = 54.4 bits (125), Expect = 6e-07
Identities = 51/192 (26%), Positives = 83/192 (43%), Gaps = 10/192 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A G + ++ L+N + N+ G +PLM A + V+ LL+ +D N
Sbjct: 1187 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINA 1246
Query: 104 -LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++ T + AC + +V L+DR + + G TPLM A S G V
Sbjct: 1247 QIETNRNTALTLACFQGRTE------VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 1300
Query: 163 AQKLLDM--QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ LLD VN TA+ A + E+LI +GA + +K T L +A
Sbjct: 1301 GRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLA 1360
Query: 221 NCHDHQVIIEIL 232
H ++++L
Sbjct: 1361 ANGGHLDVVQLL 1372
Score = 52.8 bits (121), Expect = 2e-06
Identities = 57/206 (27%), Positives = 87/206 (42%), Gaps = 16/206 (7%)
Query: 34 QISSKKKVEVALQEAIINGNMKDVEDLI-NNELKNNANIKLDSGWTPLMHACFHAQDKIV 92
+ S++ + L A G + VE L+ K + N+ S +TPL A I+
Sbjct: 1143 EAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNV---SDYTPLSLAASGGYVNII 1199
Query: 93 QYLLEKDADPNLHSDS---VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIG-DRYGQ 148
+ LL A+ N + S ++P+M A N + V L+D +N +
Sbjct: 1200 KILLNAGAEINSRTGSKLGISPLMLAAMNGHT------AAVKLLLDMGSDINAQIETNRN 1253
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT- 207
T L A GR V LLD + N+E R + G T + A E+ +L++KGA +
Sbjct: 1254 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1313
Query: 208 -EVDKSNRTLLEIANCHDHQVIIEIL 232
V S T L IA H E+L
Sbjct: 1314 PPVPSSRDTALTIAADKGHYKFCELL 1339
Score = 50.8 bits (116), Expect = 7e-06
Identities = 47/153 (30%), Positives = 72/153 (47%), Gaps = 11/153 (7%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDR 136
TPLM A KIV+ LL AD N S + T + AC+ D +V L++
Sbjct: 303 TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVD------VVKVLLES 356
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR-DQHGWTAVFWAVHHNQPEI 195
+ + G TPLM A S+G V VA+ LL+ I ++ +A+ A + E+
Sbjct: 357 GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEM 416
Query: 196 LEMLIEKGA-RLTEVDKSNRTLLEIANCHDHQV 227
+ L+E GA + + D+ + L+E C D V
Sbjct: 417 VRFLLEAGADQEHKTDEMHTALMEA--CMDGHV 447
Score = 50.8 bits (116), Expect = 7e-06
Identities = 38/135 (28%), Positives = 66/135 (48%), Gaps = 7/135 (5%)
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
D D S+ T + AC+ + +V L++R + D+ G TPL+ A ++G
Sbjct: 1074 DIDAQTESNHDTALTLACAGGHEE------LVQTLLERGASIEHRDKKGFTPLILAATAG 1127
Query: 159 RVAVAQKLLDMQVNIEMRDQHGW-TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V V + LLD +IE + + T + A + E++E+L+ +GA + S+ T L
Sbjct: 1128 HVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPL 1187
Query: 218 EIANCHDHQVIIEIL 232
+A + II+IL
Sbjct: 1188 SLAASGGYVNIIKIL 1202
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 10/178 (5%)
Query: 59 DLINNELKNNANIK--LDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMA 114
D++ L++ A+I+ ++G TPLM A ++ + LLE A N HS+ + +
Sbjct: 348 DVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTL 407
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
AC + +V L++ T LM A G V VA+ LLD +
Sbjct: 408 ACYKGHLE------MVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 461
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
M + + A E+ +LIE+GA L EV+ T L A H+ ++ +L
Sbjct: 462 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 519
Score = 49.6 bits (113), Expect = 2e-05
Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 18/202 (8%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A G + +V D + +K A+I+L TPLM A ++V+YLL A
Sbjct: 535 ETALTLACCGGFL-EVADFL---IKAGADIELGCS-TPLMEAAQEGHLELVKYLLAAGA- 588
Query: 102 PNLHSDSVTPIMA---ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
N+H+ + T A AC N D + L+ L G+TPLM+A +G
Sbjct: 589 -NVHATTATGDTALTYACENGHTDVADV------LLQAGADLEHESEGGRTPLMKAARAG 641
Query: 159 RVAVAQKLLDMQVNIEMRD-QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-L 216
V Q L+ N+ + T + A ++E+L+ GA T K T L
Sbjct: 642 HVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 701
Query: 217 LEIANCHDHQVIIEILKKSLNL 238
+E A V+ +L NL
Sbjct: 702 IEAAKGGHTSVVCYLLDYPNNL 723
Score = 46.8 bits (106), Expect = 1e-04
Identities = 45/190 (23%), Positives = 86/190 (45%), Gaps = 10/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A G++K V+ L+ + K + N + +G T L +AC +V+ LLE A
Sbjct: 305 LMAAANGGHVKIVKLLLAH--KADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 362
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAV 162
H+++ TP+M A S + + L++ +N + + ++ L A G + +
Sbjct: 363 HNENGHTPLMEAGSAGHVE------VARLLLENGAGINTHSNEFKESALTLACYKGHLEM 416
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LL+ + E + TA+ A E+ +L++ GA++ S + L +A C
Sbjct: 417 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 476
Query: 223 HDHQVIIEIL 232
H + +L
Sbjct: 477 GGHVELAALL 486
Score = 45.2 bits (102), Expect = 4e-04
Identities = 46/195 (23%), Positives = 89/195 (45%), Gaps = 14/195 (7%)
Query: 58 EDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIM 113
E+L+ L+ A+I+ G+TPL+ A +V+ LL+ AD S+ TP+
Sbjct: 1096 EELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLS 1155
Query: 114 AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD--MQV 171
ACS + +V L+ R + TPL A S G V + + LL+ ++
Sbjct: 1156 LACSGGRQE------VVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI 1209
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIANCHDH-QVII 229
N + G + + A + +++L++ G+ + +++ + T L +A +V+
Sbjct: 1210 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS 1269
Query: 230 EILKKSLNLDDDHKT 244
+L + N++ KT
Sbjct: 1270 LLLDRKANVEHRAKT 1284
Score = 43.6 bits (98), Expect = 0.001
Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 12/160 (7%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSD--SVTPIMAACSNSSADNDTIYSIVCNLID 135
T L AC +++VQ LLE+ A H D TP++ A + +V L+D
Sbjct: 1085 TALTLACAGGHEELVQTLLERGASIE-HRDKKGFTPLILAATAGHV------GVVEILLD 1137
Query: 136 RNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+ +R TPL A S GR V + LL N E R+ +T + A
Sbjct: 1138 NGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVN 1197
Query: 195 ILEMLIEKGARLTEVDKSNRTL--LEIANCHDHQVIIEIL 232
I+++L+ GA + S + L +A + H +++L
Sbjct: 1198 IIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLL 1237
Score = 35.5 bits (78), Expect = 0.29
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG-WTAVFWAVHHNQPEILEMLIEKGAR 205
G++ L A S+G +AQ LL M N+E R G T + A + +I+++L+ A
Sbjct: 267 GESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKAD 326
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSY 249
+ + T L A + ++++L +S +DH +EN +
Sbjct: 327 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDH--NENGH 368
>AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined
breast cancer antigen NY-BR-16 protein.
Length = 1188
Score = 56.4 bits (130), Expect = 1e-07
Identities = 43/176 (24%), Positives = 83/176 (47%), Gaps = 11/176 (6%)
Query: 65 LKNNANIKLDSGW---TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSS 120
L+N A I S + L AC+ ++V++LLE AD +D + T +M AC +
Sbjct: 387 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGH 446
Query: 121 ADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG 180
+ + L+D +N+ ++PL A G V +A L++ ++E + G
Sbjct: 447 VE------VARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEG 500
Query: 181 WTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+T + A E++ +L+ +GA + + +++ T L +A C + + L K+
Sbjct: 501 YTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKA 556
Score = 50.8 bits (116), Expect = 7e-06
Identities = 47/153 (30%), Positives = 72/153 (47%), Gaps = 11/153 (7%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDR 136
TPLM A KIV+ LL AD N S + T + AC+ D +V L++
Sbjct: 303 TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVD------VVKVLLES 356
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR-DQHGWTAVFWAVHHNQPEI 195
+ + G TPLM A S+G V VA+ LL+ I ++ +A+ A + E+
Sbjct: 357 GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEM 416
Query: 196 LEMLIEKGA-RLTEVDKSNRTLLEIANCHDHQV 227
+ L+E GA + + D+ + L+E C D V
Sbjct: 417 VRFLLEAGADQEHKTDEMHTALMEA--CMDGHV 447
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 10/178 (5%)
Query: 59 DLINNELKNNANIK--LDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMA 114
D++ L++ A+I+ ++G TPLM A ++ + LLE A N HS+ + +
Sbjct: 348 DVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTL 407
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
AC + +V L++ T LM A G V VA+ LLD +
Sbjct: 408 ACYKGHLE------MVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 461
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
M + + A E+ +LIE+GA L EV+ T L A H+ ++ +L
Sbjct: 462 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 519
Score = 46.8 bits (106), Expect = 1e-04
Identities = 45/190 (23%), Positives = 86/190 (45%), Gaps = 10/190 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A G++K V+ L+ + K + N + +G T L +AC +V+ LLE A
Sbjct: 305 LMAAANGGHVKIVKLLLAH--KADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 362
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVAV 162
H+++ TP+M A S + + L++ +N + + ++ L A G + +
Sbjct: 363 HNENGHTPLMEAGSAGHVE------VARLLLENGAGINTHSNEFKESALTLACYKGHLEM 416
Query: 163 AQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC 222
+ LL+ + E + TA+ A E+ +L++ GA++ S + L +A C
Sbjct: 417 VRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAAC 476
Query: 223 HDHQVIIEIL 232
H + +L
Sbjct: 477 GGHVELAALL 486
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/205 (23%), Positives = 81/205 (39%), Gaps = 11/205 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA G+ + V L+ NA + ++ T L AC ++ +L++ AD L
Sbjct: 504 LMEAAREGHEEMVALLLGQGANINAQTE-ETQETALTLACCGGFLEVADFLIKAGADIEL 562
Query: 105 HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQ 164
TP+M A + +V L+ ++ G T L A +G VA
Sbjct: 563 GCS--TPLMEAAQEGHLE------LVKYLLAAGANVHATTATGDTALTYACENGHTDVAD 614
Query: 165 KLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANC-H 223
LL ++E + G T + A ++ LI KGA + T+L C
Sbjct: 615 VLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGAECESEPQLIMTILSALACAG 674
Query: 224 DHQVIIEILKKSLNLDDDHKTDENS 248
H ++E+L + D H+ + S
Sbjct: 675 GHLAVVELL-LAHGADPTHRLKDGS 698
Score = 35.5 bits (78), Expect = 0.29
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG-WTAVFWAVHHNQPEILEMLIEKGAR 205
G++ L A S+G +AQ LL M N+E R G T + A + +I+++L+ A
Sbjct: 267 GESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKAD 326
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSY 249
+ + T L A + ++++L +S +DH +EN +
Sbjct: 327 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDH--NENGH 368
>AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein.
Length = 2486
Score = 56.4 bits (130), Expect = 1e-07
Identities = 43/176 (24%), Positives = 83/176 (47%), Gaps = 11/176 (6%)
Query: 65 LKNNANIKLDSGW---TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSS 120
L+N A I S + L AC+ ++V++LLE AD +D + T +M AC +
Sbjct: 271 LENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGH 330
Query: 121 ADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG 180
+ + L+D +N+ ++PL A G V +A L++ ++E + G
Sbjct: 331 VE------VARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEG 384
Query: 181 WTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIANCHDHQVIIEILKKS 235
+T + A E++ +L+ +GA + + +++ T L +A C + + L K+
Sbjct: 385 YTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKA 440
Score = 54.4 bits (125), Expect = 6e-07
Identities = 51/192 (26%), Positives = 83/192 (43%), Gaps = 10/192 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN- 103
L A G + ++ L+N + N+ G +PLM A + V+ LL+ +D N
Sbjct: 1070 LSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINA 1129
Query: 104 -LHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAV 162
+ ++ T + AC + +V L+DR + + G TPLM A S G V
Sbjct: 1130 QIETNRNTALTLACFQGRTE------VVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEV 1183
Query: 163 AQKLLDM--QVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ LLD VN TA+ A + E+LI +GA + +K T L +A
Sbjct: 1184 GRVLLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLA 1243
Query: 221 NCHDHQVIIEIL 232
H ++++L
Sbjct: 1244 ANGGHLDVVQLL 1255
Score = 52.8 bits (121), Expect = 2e-06
Identities = 57/206 (27%), Positives = 87/206 (42%), Gaps = 16/206 (7%)
Query: 34 QISSKKKVEVALQEAIINGNMKDVEDLI-NNELKNNANIKLDSGWTPLMHACFHAQDKIV 92
+ S++ + L A G + VE L+ K + N+ S +TPL A I+
Sbjct: 1026 EAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNV---SDYTPLSLAASGGYVNII 1082
Query: 93 QYLLEKDADPNLHSDS---VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIG-DRYGQ 148
+ LL A+ N + S ++P+M A N + V L+D +N +
Sbjct: 1083 KILLNAGAEINSRTGSKLGISPLMLAAMNGHT------AAVKLLLDMGSDINAQIETNRN 1136
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT- 207
T L A GR V LLD + N+E R + G T + A E+ +L++KGA +
Sbjct: 1137 TALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNA 1196
Query: 208 -EVDKSNRTLLEIANCHDHQVIIEIL 232
V S T L IA H E+L
Sbjct: 1197 PPVPSSRDTALTIAADKGHYKFCELL 1222
Score = 50.8 bits (116), Expect = 7e-06
Identities = 38/135 (28%), Positives = 66/135 (48%), Gaps = 7/135 (5%)
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
D D S+ T + AC+ + +V L++R + D+ G TPL+ A ++G
Sbjct: 957 DIDAQTESNHDTALTLACAGGHEE------LVQTLLERGASIEHRDKKGFTPLILAATAG 1010
Query: 159 RVAVAQKLLDMQVNIEMRDQHGW-TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLL 217
V V + LLD +IE + + T + A + E++E+L+ +GA + S+ T L
Sbjct: 1011 HVGVVEILLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPL 1070
Query: 218 EIANCHDHQVIIEIL 232
+A + II+IL
Sbjct: 1071 SLAASGGYVNIIKIL 1085
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/178 (26%), Positives = 78/178 (43%), Gaps = 10/178 (5%)
Query: 59 DLINNELKNNANIK--LDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIMA 114
D++ L++ A+I+ ++G TPLM A ++ + LLE A N HS+ + +
Sbjct: 232 DVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTL 291
Query: 115 ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIE 174
AC + +V L++ T LM A G V VA+ LLD +
Sbjct: 292 ACYKGHLE------MVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVN 345
Query: 175 MRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
M + + A E+ +LIE+GA L EV+ T L A H+ ++ +L
Sbjct: 346 MPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 403
Score = 49.6 bits (113), Expect = 2e-05
Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 18/202 (8%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A G + +V D + +K A+I+L TPLM A ++V+YLL A
Sbjct: 419 ETALTLACCGGFL-EVADFL---IKAGADIELGCS-TPLMEAAQEGHLELVKYLLAAGA- 472
Query: 102 PNLHSDSVTPIMA---ACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
N+H+ + T A AC N D + L+ L G+TPLM+A +G
Sbjct: 473 -NVHATTATGDTALTYACENGHTDVADV------LLQAGADLEHESEGGRTPLMKAARAG 525
Query: 159 RVAVAQKLLDMQVNIEMRD-QHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRT-L 216
V Q L+ N+ + T + A ++E+L+ GA T K T L
Sbjct: 526 HVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 585
Query: 217 LEIANCHDHQVIIEILKKSLNL 238
+E A V+ +L NL
Sbjct: 586 IEAAKGGHTSVVCYLLDYPNNL 607
Score = 47.6 bits (108), Expect = 7e-05
Identities = 46/153 (30%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDR 136
T LM A KIV+ LL AD N S + T + AC+ D +V L++
Sbjct: 187 TSLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVD------VVKVLLES 240
Query: 137 NCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR-DQHGWTAVFWAVHHNQPEI 195
+ + G TPLM A S+G V VA+ LL+ I ++ +A+ A + E+
Sbjct: 241 GASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEM 300
Query: 196 LEMLIEKGA-RLTEVDKSNRTLLEIANCHDHQV 227
+ L+E GA + + D+ + L+E C D V
Sbjct: 301 VRFLLEAGADQEHKTDEMHTALMEA--CMDGHV 331
Score = 47.2 bits (107), Expect = 9e-05
Identities = 45/191 (23%), Positives = 87/191 (45%), Gaps = 10/191 (5%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
+L A G++K V+ L+ + K + N + +G T L +AC +V+ LLE A
Sbjct: 188 SLMAAANGGHVKIVKLLLAH--KADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIE 245
Query: 104 LHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNI-GDRYGQTPLMRAISSGRVA 161
H+++ TP+M A S + + L++ +N + + ++ L A G +
Sbjct: 246 DHNENGHTPLMEAGSAGHVE------VARLLLENGAGINTHSNEFKESALTLACYKGHLE 299
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
+ + LL+ + E + TA+ A E+ +L++ GA++ S + L +A
Sbjct: 300 MVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAA 359
Query: 222 CHDHQVIIEIL 232
C H + +L
Sbjct: 360 CGGHVELAALL 370
Score = 45.2 bits (102), Expect = 4e-04
Identities = 46/195 (23%), Positives = 89/195 (45%), Gaps = 14/195 (7%)
Query: 58 EDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSV--TPIM 113
E+L+ L+ A+I+ G+TPL+ A +V+ LL+ AD S+ TP+
Sbjct: 979 EELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLS 1038
Query: 114 AACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLD--MQV 171
ACS + +V L+ R + TPL A S G V + + LL+ ++
Sbjct: 1039 LACSGGRQE------VVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEI 1092
Query: 172 NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL-TEVDKSNRTLLEIANCHDH-QVII 229
N + G + + A + +++L++ G+ + +++ + T L +A +V+
Sbjct: 1093 NSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRTEVVS 1152
Query: 230 EILKKSLNLDDDHKT 244
+L + N++ KT
Sbjct: 1153 LLLDRKANVEHRAKT 1167
Score = 43.6 bits (98), Expect = 0.001
Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 12/160 (7%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSD--SVTPIMAACSNSSADNDTIYSIVCNLID 135
T L AC +++VQ LLE+ A H D TP++ A + +V L+D
Sbjct: 968 TALTLACAGGHEELVQTLLERGASIE-HRDKKGFTPLILAATAGHV------GVVEILLD 1020
Query: 136 RNCILNI-GDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+ +R TPL A S GR V + LL N E R+ +T + A
Sbjct: 1021 NGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVN 1080
Query: 195 ILEMLIEKGARLTEVDKSNRTL--LEIANCHDHQVIIEIL 232
I+++L+ GA + S + L +A + H +++L
Sbjct: 1081 IIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLL 1120
Score = 36.3 bits (80), Expect = 0.17
Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHG-WTAVFWAVHHNQPEILEMLIEKGAR 205
G++ L A S+G +AQ LL M N+E R G T++ A + +I+++L+ A
Sbjct: 151 GESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITSLMAAANGGHVKIVKLLLAHKAD 210
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSY 249
+ + T L A + ++++L +S +DH +EN +
Sbjct: 211 VNAQSSTGNTALTYACAGGYVDVVKVLLESGASIEDH--NENGH 252
>Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein.
Length = 3925
Score = 56.0 bits (129), Expect = 2e-07
Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNL 133
+G TPL A + K+ LLEK A P+ + + TP+ A + I L
Sbjct: 595 NGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQ------IASTL 648
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
++ NI + G TPL A G + LLD NI M + G T++ A ++
Sbjct: 649 LNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKV 708
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCH--DHQVIIEILKKSLNLD 239
+ ++L + GA K T L +A CH + +++ +LK+ N++
Sbjct: 709 NVADILTKHGADQDAHTKLGYTPLIVA-CHYGNVKMVNFLLKQGANVN 755
Score = 54.0 bits (124), Expect = 8e-07
Identities = 48/180 (26%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A G ++ V L+ N +A + + TPL A + +IVQ LL+ A
Sbjct: 465 ETALHMAARAGQVEVVRCLLRNGALVDARAREEQ--TPLHIASRLGKTEIVQLLLQHMAH 522
Query: 102 PNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
P+ + + TP+ + D ++ L++ ++ + G TPL A G +
Sbjct: 523 PDAATTNGYTPLHISAREGQVDVASV------LLEAGAAHSLATKKGFTPLHVAAKYGSL 576
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA+ LL + + ++G T + A H++ ++ +L+EKGA K+ T L IA
Sbjct: 577 DVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIA 636
Score = 51.6 bits (118), Expect = 4e-06
Identities = 40/164 (24%), Positives = 69/164 (42%), Gaps = 5/164 (3%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSI 129
NI G TPL A +V LL+K A N+H + + + + + D + I
Sbjct: 656 NIVTKQGVTPLHLASQEGHTDMVTLLLDKGA--NIHMSTKSGLTSLHLAAQEDKVNVADI 713
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
L + + G TPL+ A G V + LL N+ + ++G+T + A
Sbjct: 714 ---LTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQ 770
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
I+ +L++ GA+ + T L IA + +++ LK
Sbjct: 771 QGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLK 814
Score = 49.2 bits (112), Expect = 2e-05
Identities = 46/201 (22%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ + V L+ N+ K + P +H D K LL+ D + +
Sbjct: 167 LAVALQQGHNQAVAILLENDTKGKVRL-------PALHIAARKDDTKSAALLLQNDHNAD 219
Query: 104 LHSDSVTPIMAACSNSSADNDTIY---SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
+ S + + Y ++ L++R ++ R G TPL A G
Sbjct: 220 VQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNT 279
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ + LLD I+ + + G T + A +++E+L+E+GA L K+ + L +A
Sbjct: 280 NMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMA 339
Query: 221 NCHDH-QVIIEILKKSLNLDD 240
DH + + +L+ +DD
Sbjct: 340 AQGDHVECVKHLLQHKAPVDD 360
Score = 48.4 bits (110), Expect = 4e-05
Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 5/147 (3%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNL 133
+SG TP+ A F IV LL+ A P+ VT I + A +V L
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPD-----VTNIRGETALHMAARAGQVEVVRCL 483
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ +++ R QTPL A G+ + Q LL + + +G+T + + Q
Sbjct: 484 LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQV 543
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIA 220
++ +L+E GA + K T L +A
Sbjct: 544 DVASVLLEAGAAHSLATKKGFTPLHVA 570
Score = 47.6 bits (108), Expect = 7e-05
Identities = 49/189 (25%), Positives = 88/189 (46%), Gaps = 9/189 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A GN V+ L++ + +A K G TPL A D++V+ LLE+ A
Sbjct: 270 LHVASKRGNTNMVKLLLDRGGQIDA--KTRDGLTPLHCAARSGHDQVVELLLERGAPLLA 327
Query: 105 HS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ + ++P+ A A D + + L + + ++ Y T L A G V
Sbjct: 328 RTKNGLSPLHMA-----AQGDHVECVKHLLQHKAPVDDVTLDY-LTALHVAAHCGHYRVT 381
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ LLD + N R +G+T + A N+ +++E+L++ GA + + +S T + +A
Sbjct: 382 KLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFM 441
Query: 224 DHQVIIEIL 232
H I+ +L
Sbjct: 442 GHLNIVLLL 450
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/104 (25%), Positives = 50/104 (48%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ R ++ + G T L A +G+ V + L+ NI + Q+G+T ++ A
Sbjct: 79 LVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAA 138
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
N ++++ L+E GA + + T L +A H + IL
Sbjct: 139 QENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAIL 182
Score = 47.2 bits (107), Expect = 9e-05
Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 5/177 (2%)
Query: 59 DLINNELKNNAN--IKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
D++ L+N AN + G+TPL A ++ V LLE D + ++ +AA
Sbjct: 144 DVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALH--IAAR 201
Query: 117 SNSSADNDTIYSIVCNL-IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + + N + ++N G TPL A G V VA LL+ ++
Sbjct: 202 KDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF 261
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++G T + A ++++L+++G ++ + T L A H ++E+L
Sbjct: 262 TARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELL 318
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
G+TPL A + + + LL++ A + + +TP+ A + DN + + L+
Sbjct: 563 GFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVA---AHYDNQKVALL---LL 616
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ + + G TPL A ++ +A LL+ + + G T + A +
Sbjct: 617 EKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTD 676
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDH 242
++ +L++KGA + KS T L +A D + +IL K D H
Sbjct: 677 MVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAH 724
Score = 43.2 bits (97), Expect = 0.001
Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 11/205 (5%)
Query: 32 SSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKI 91
SS S+ KK AL A + G + V+ L+ N N + +G+TPL A +
Sbjct: 88 SSVDSATKKGNTALHIASLAGQAEVVKVLVKEGA--NINAQSQNGFTPLYMAAQENHIDV 145
Query: 92 VQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLID---RNCILNIGDRYG 147
V+YLLE A+ + + D TP+ A N + ++ N R L+I R
Sbjct: 146 VKYLLENGANQSTATEDGFTPLAVAL--QQGHNQAVAILLENDTKGKVRLPALHIAARKD 203
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
T A+ A M VN + G+T + A H+ + +L+ +GA +
Sbjct: 204 DTK-SAALLLQNDHNADVQSKMMVN--RTTESGFTPLHIAAHYGNVNVATLLLNRGAAVD 260
Query: 208 EVDKSNRTLLEIANCHDHQVIIEIL 232
++ T L +A+ + ++++L
Sbjct: 261 FTARNGITPLHVASKRGNTNMVKLL 285
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL 206
G TPL + G+V VA LL+ + + G+T + A + ++ ++L+++ A
Sbjct: 530 GYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA 589
Query: 207 TEVDKSNRTLLEIANCHDHQ-VIIEILKKSLNLDDDHKTDENSY 249
K+ T L +A +D+Q V + +L+K + H T +N Y
Sbjct: 590 DSAGKNGLTPLHVAAHYDNQKVALLLLEKGAS---PHATAKNGY 630
Score = 35.1 bits (77), Expect = 0.39
Identities = 52/226 (23%), Positives = 91/226 (40%), Gaps = 14/226 (6%)
Query: 30 DYSSQISSKKKVEVA-LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQ 88
D QI +K + + L A +G+ + VE L+ A K +G +PL A
Sbjct: 287 DRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTK--NGLSPLHMAAQGDH 344
Query: 89 DKIVQYLLEKDA---DPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDR 145
+ V++LL+ A D L + + A C + Y + L+D+ N
Sbjct: 345 VECVKHLLQHKAPVDDVTLDYLTALHVAAHCGH--------YRVTKLLLDKRANPNARAL 396
Query: 146 YGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGAR 205
G TPL A R+ V + L+ +I+ + G T + A I+ +L++ GA
Sbjct: 397 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 456
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLN 251
+ T L +A ++ L ++ L D +E + L+
Sbjct: 457 PDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLH 502
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ N N K +G+TPL A I+ LL+ A PN
Sbjct: 739 GNVKMVNFLLKQGA--NVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPN 788
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/83 (21%), Positives = 39/83 (46%)
Query: 152 MRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+RA +G + + L ++I +Q+G A+ A +++ L+ +G+ + K
Sbjct: 36 LRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATK 95
Query: 212 SNRTLLEIANCHDHQVIIEILKK 234
T L IA+ ++++L K
Sbjct: 96 KGNTALHIASLAGQAEVVKVLVK 118
Score = 31.1 bits (67), Expect = 6.3
Identities = 30/134 (22%), Positives = 52/134 (38%), Gaps = 9/134 (6%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ +N + G TPL A + V + LL+ N + G+T + A+
Sbjct: 112 VVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVAL 171
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENS 248
+ + +L+E + K L IA D + +L L +DH D S
Sbjct: 172 QQGHNQAVAILLENDTK----GKVRLPALHIAARKD-----DTKSAALLLQNDHNADVQS 222
Query: 249 YLNHQLTSWQDYYP 262
+ T+ + P
Sbjct: 223 KMMVNRTTESGFTP 236
>X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein.
Length = 1872
Score = 56.0 bits (129), Expect = 2e-07
Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNL 133
+G TPL A + K+ LLEK A P+ + + TP+ A + I L
Sbjct: 595 NGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQ------IASTL 648
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
++ NI + G TPL A G + LLD NI M + G T++ A ++
Sbjct: 649 LNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKV 708
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCH--DHQVIIEILKKSLNLD 239
+ ++L + GA K T L +A CH + +++ +LK+ N++
Sbjct: 709 NVADILTKHGADQDAHTKLGYTPLIVA-CHYGNVKMVNFLLKQGANVN 755
Score = 54.0 bits (124), Expect = 8e-07
Identities = 48/180 (26%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A G ++ V L+ N +A + + TPL A + +IVQ LL+ A
Sbjct: 465 ETALHMAARAGQVEVVRCLLRNGALVDARAREEQ--TPLHIASRLGKTEIVQLLLQHMAH 522
Query: 102 PNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
P+ + + TP+ + D ++ L++ ++ + G TPL A G +
Sbjct: 523 PDAATTNGYTPLHISAREGQVDVASV------LLEAGAAHSLATKKGFTPLHVAAKYGSL 576
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA+ LL + + ++G T + A H++ ++ +L+EKGA K+ T L IA
Sbjct: 577 DVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIA 636
Score = 51.6 bits (118), Expect = 4e-06
Identities = 40/164 (24%), Positives = 69/164 (42%), Gaps = 5/164 (3%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSI 129
NI G TPL A +V LL+K A N+H + + + + + D + I
Sbjct: 656 NIVTKQGVTPLHLASQEGHTDMVTLLLDKGA--NIHMSTKSGLTSLHLAAQEDKVNVADI 713
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
L + + G TPL+ A G V + LL N+ + ++G+T + A
Sbjct: 714 ---LTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQ 770
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
I+ +L++ GA+ + T L IA + +++ LK
Sbjct: 771 QGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLK 814
Score = 49.2 bits (112), Expect = 2e-05
Identities = 46/201 (22%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ + V L+ N+ K + P +H D K LL+ D + +
Sbjct: 167 LAVALQQGHNQAVAILLENDTKGKVRL-------PALHIAARKDDTKSAALLLQNDHNAD 219
Query: 104 LHSDSVTPIMAACSNSSADNDTIY---SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
+ S + + Y ++ L++R ++ R G TPL A G
Sbjct: 220 VQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNT 279
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ + LLD I+ + + G T + A +++E+L+E+GA L K+ + L +A
Sbjct: 280 NMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMA 339
Query: 221 NCHDH-QVIIEILKKSLNLDD 240
DH + + +L+ +DD
Sbjct: 340 AQGDHVECVKHLLQHKAPVDD 360
Score = 48.4 bits (110), Expect = 4e-05
Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 5/147 (3%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNL 133
+SG TP+ A F IV LL+ A P+ VT I + A +V L
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPD-----VTNIRGETALHMAARAGQVEVVRCL 483
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ +++ R QTPL A G+ + Q LL + + +G+T + + Q
Sbjct: 484 LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQV 543
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIA 220
++ +L+E GA + K T L +A
Sbjct: 544 DVASVLLEAGAAHSLATKKGFTPLHVA 570
Score = 47.6 bits (108), Expect = 7e-05
Identities = 49/189 (25%), Positives = 88/189 (46%), Gaps = 9/189 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A GN V+ L++ + +A K G TPL A D++V+ LLE+ A
Sbjct: 270 LHVASKRGNTNMVKLLLDRGGQIDA--KTRDGLTPLHCAARSGHDQVVELLLERGAPLLA 327
Query: 105 HS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ + ++P+ A A D + + L + + ++ Y T L A G V
Sbjct: 328 RTKNGLSPLHMA-----AQGDHVECVKHLLQHKAPVDDVTLDY-LTALHVAAHCGHYRVT 381
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ LLD + N R +G+T + A N+ +++E+L++ GA + + +S T + +A
Sbjct: 382 KLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFM 441
Query: 224 DHQVIIEIL 232
H I+ +L
Sbjct: 442 GHLNIVLLL 450
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/104 (25%), Positives = 50/104 (48%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ R ++ + G T L A +G+ V + L+ NI + Q+G+T ++ A
Sbjct: 79 LVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAA 138
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
N ++++ L+E GA + + T L +A H + IL
Sbjct: 139 QENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAIL 182
Score = 47.2 bits (107), Expect = 9e-05
Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 5/177 (2%)
Query: 59 DLINNELKNNAN--IKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
D++ L+N AN + G+TPL A ++ V LLE D + ++ +AA
Sbjct: 144 DVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALH--IAAR 201
Query: 117 SNSSADNDTIYSIVCNL-IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + + N + ++N G TPL A G V VA LL+ ++
Sbjct: 202 KDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF 261
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++G T + A ++++L+++G ++ + T L A H ++E+L
Sbjct: 262 TARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELL 318
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
G+TPL A + + + LL++ A + + +TP+ A + DN + + L+
Sbjct: 563 GFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVA---AHYDNQKVALL---LL 616
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ + + G TPL A ++ +A LL+ + + G T + A +
Sbjct: 617 EKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTD 676
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDH 242
++ +L++KGA + KS T L +A D + +IL K D H
Sbjct: 677 MVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAH 724
Score = 43.2 bits (97), Expect = 0.001
Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 11/205 (5%)
Query: 32 SSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKI 91
SS S+ KK AL A + G + V+ L+ N N + +G+TPL A +
Sbjct: 88 SSVDSATKKGNTALHIASLAGQAEVVKVLVKEGA--NINAQSQNGFTPLYMAAQENHIDV 145
Query: 92 VQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLID---RNCILNIGDRYG 147
V+YLLE A+ + + D TP+ A N + ++ N R L+I R
Sbjct: 146 VKYLLENGANQSTATEDGFTPLAVAL--QQGHNQAVAILLENDTKGKVRLPALHIAARKD 203
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
T A+ A M VN + G+T + A H+ + +L+ +GA +
Sbjct: 204 DTK-SAALLLQNDHNADVQSKMMVN--RTTESGFTPLHIAAHYGNVNVATLLLNRGAAVD 260
Query: 208 EVDKSNRTLLEIANCHDHQVIIEIL 232
++ T L +A+ + ++++L
Sbjct: 261 FTARNGITPLHVASKRGNTNMVKLL 285
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL 206
G TPL + G+V VA LL+ + + G+T + A + ++ ++L+++ A
Sbjct: 530 GYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA 589
Query: 207 TEVDKSNRTLLEIANCHDHQ-VIIEILKKSLNLDDDHKTDENSY 249
K+ T L +A +D+Q V + +L+K + H T +N Y
Sbjct: 590 DSAGKNGLTPLHVAAHYDNQKVALLLLEKGAS---PHATAKNGY 630
Score = 35.1 bits (77), Expect = 0.39
Identities = 52/226 (23%), Positives = 91/226 (40%), Gaps = 14/226 (6%)
Query: 30 DYSSQISSKKKVEVA-LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQ 88
D QI +K + + L A +G+ + VE L+ A K +G +PL A
Sbjct: 287 DRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTK--NGLSPLHMAAQGDH 344
Query: 89 DKIVQYLLEKDA---DPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDR 145
+ V++LL+ A D L + + A C + Y + L+D+ N
Sbjct: 345 VECVKHLLQHKAPVDDVTLDYLTALHVAAHCGH--------YRVTKLLLDKRANPNARAL 396
Query: 146 YGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGAR 205
G TPL A R+ V + L+ +I+ + G T + A I+ +L++ GA
Sbjct: 397 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 456
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLN 251
+ T L +A ++ L ++ L D +E + L+
Sbjct: 457 PDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLH 502
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ N N K +G+TPL A I+ LL+ A PN
Sbjct: 739 GNVKMVNFLLKQGA--NVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPN 788
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/83 (21%), Positives = 39/83 (46%)
Query: 152 MRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+RA +G + + L ++I +Q+G A+ A +++ L+ +G+ + K
Sbjct: 36 LRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATK 95
Query: 212 SNRTLLEIANCHDHQVIIEILKK 234
T L IA+ ++++L K
Sbjct: 96 KGNTALHIASLAGQAEVVKVLVK 118
Score = 31.1 bits (67), Expect = 6.3
Identities = 30/134 (22%), Positives = 52/134 (38%), Gaps = 9/134 (6%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ +N + G TPL A + V + LL+ N + G+T + A+
Sbjct: 112 VVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVAL 171
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENS 248
+ + +L+E + K L IA D + +L L +DH D S
Sbjct: 172 QQGHNQAVAILLENDTK----GKVRLPALHIAARKD-----DTKSAALLLQNDHNADVQS 222
Query: 249 YLNHQLTSWQDYYP 262
+ T+ + P
Sbjct: 223 KMMVNRTTESGFTP 236
>BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein
protein.
Length = 1863
Score = 56.0 bits (129), Expect = 2e-07
Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 10/168 (5%)
Query: 75 SGWTPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNL 133
+G TPL A + K+ LLEK A P+ + + TP+ A + I L
Sbjct: 574 NGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQ------IASTL 627
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
++ NI + G TPL A G + LLD NI M + G T++ A ++
Sbjct: 628 LNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKV 687
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIANCH--DHQVIIEILKKSLNLD 239
+ ++L + GA K T L +A CH + +++ +LK+ N++
Sbjct: 688 NVADILTKHGADQDAHTKLGYTPLIVA-CHYGNVKMVNFLLKQGANVN 734
Score = 54.0 bits (124), Expect = 8e-07
Identities = 48/180 (26%), Positives = 83/180 (46%), Gaps = 9/180 (5%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
E AL A G ++ V L+ N +A + + TPL A + +IVQ LL+ A
Sbjct: 444 ETALHMAARAGQVEVVRCLLRNGALVDARAREEQ--TPLHIASRLGKTEIVQLLLQHMAH 501
Query: 102 PNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
P+ + + TP+ + D ++ L++ ++ + G TPL A G +
Sbjct: 502 PDAATTNGYTPLHISAREGQVDVASV------LLEAGAAHSLATKKGFTPLHVAAKYGSL 555
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
VA+ LL + + ++G T + A H++ ++ +L+EKGA K+ T L IA
Sbjct: 556 DVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIA 615
Score = 51.6 bits (118), Expect = 4e-06
Identities = 40/164 (24%), Positives = 69/164 (42%), Gaps = 5/164 (3%)
Query: 70 NIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSI 129
NI G TPL A +V LL+K A N+H + + + + + D + I
Sbjct: 635 NIVTKQGVTPLHLASQEGHTDMVTLLLDKGA--NIHMSTKSGLTSLHLAAQEDKVNVADI 692
Query: 130 VCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVH 189
L + + G TPL+ A G V + LL N+ + ++G+T + A
Sbjct: 693 ---LTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQ 749
Query: 190 HNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILK 233
I+ +L++ GA+ + T L IA + +++ LK
Sbjct: 750 QGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLK 793
Score = 49.6 bits (113), Expect = 2e-05
Identities = 46/201 (22%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQD-KIVQYLLEKDADPN 103
L A+ G+ + V L+ N+ K + P +H D K LL+ D + +
Sbjct: 146 LAVALQQGHNQAVAILLENDTKGKVRL-------PALHIAARKDDTKSAALLLQNDHNAD 198
Query: 104 LHSDSVTPIMAACSNSSADNDTIY---SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
+ S + + Y ++ L++R ++ R G TPL A G
Sbjct: 199 IQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNT 258
Query: 161 AVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA 220
+ + LLD I+ + + G T + A +++E+L+E+GA L K+ + L +A
Sbjct: 259 NMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMA 318
Query: 221 NCHDH-QVIIEILKKSLNLDD 240
DH + + +L+ +DD
Sbjct: 319 AQGDHVECVKHLLQHKAPVDD 339
Score = 48.4 bits (110), Expect = 4e-05
Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 5/147 (3%)
Query: 74 DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNL 133
+SG TP+ A F IV LL+ A P+ VT I + A +V L
Sbjct: 408 ESGLTPIHVAAFMGHLNIVLLLLQNGASPD-----VTNIRGETALHMAARAGQVEVVRCL 462
Query: 134 IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP 193
+ +++ R QTPL A G+ + Q LL + + +G+T + + Q
Sbjct: 463 LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQV 522
Query: 194 EILEMLIEKGARLTEVDKSNRTLLEIA 220
++ +L+E GA + K T L +A
Sbjct: 523 DVASVLLEAGAAHSLATKKGFTPLHVA 549
Score = 47.6 bits (108), Expect = 7e-05
Identities = 42/177 (23%), Positives = 77/177 (43%), Gaps = 5/177 (2%)
Query: 59 DLINNELKNNAN--IKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
D++ L+N AN + G+TPL A ++ V LLE D + ++ +AA
Sbjct: 123 DVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALH--IAAR 180
Query: 117 SNSSADNDTIYSIVCNL-IDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEM 175
+ + + N I ++N G TPL A G V VA LL+ ++
Sbjct: 181 KDDTKSAALLLQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF 240
Query: 176 RDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++G T + A ++++L+++G ++ + T L A H ++E+L
Sbjct: 241 TARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELL 297
Score = 47.6 bits (108), Expect = 7e-05
Identities = 49/189 (25%), Positives = 88/189 (46%), Gaps = 9/189 (4%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L A GN V+ L++ + +A K G TPL A D++V+ LLE+ A
Sbjct: 249 LHVASKRGNTNMVKLLLDRGGQIDA--KTRDGLTPLHCAARSGHDQVVELLLERGAPLLA 306
Query: 105 HS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ + ++P+ A A D + + L + + ++ Y T L A G V
Sbjct: 307 RTKNGLSPLHMA-----AQGDHVECVKHLLQHKAPVDDVTLDY-LTALHVAAHCGHYRVT 360
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCH 223
+ LLD + N R +G+T + A N+ +++E+L++ GA + + +S T + +A
Sbjct: 361 KLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFM 420
Query: 224 DHQVIIEIL 232
H I+ +L
Sbjct: 421 GHLNIVLLL 429
Score = 47.2 bits (107), Expect = 9e-05
Identities = 27/104 (25%), Positives = 50/104 (48%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ R ++ + G T L A +G+ V + L+ NI + Q+G+T ++ A
Sbjct: 58 LVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAA 117
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
N ++++ L+E GA + + T L +A H + IL
Sbjct: 118 QENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAIL 161
Score = 46.8 bits (106), Expect = 1e-04
Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 7/168 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
G+TPL A + + + LL++ A + + +TP+ A + DN + + L+
Sbjct: 542 GFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVA---AHYDNQKVALL---LL 595
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ + + G TPL A ++ +A LL+ + + G T + A +
Sbjct: 596 EKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTD 655
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDH 242
++ +L++KGA + KS T L +A D + +IL K D H
Sbjct: 656 MVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAH 703
Score = 42.7 bits (96), Expect = 0.002
Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 11/205 (5%)
Query: 32 SSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKI 91
SS S+ KK AL A + G + V+ L+ N N + +G+TPL A +
Sbjct: 67 SSVDSATKKGNTALHIASLAGQAEVVKVLVKEGA--NINAQSQNGFTPLYMAAQENHIDV 124
Query: 92 VQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLID---RNCILNIGDRYG 147
V+YLLE A+ + + D TP+ A N + ++ N R L+I R
Sbjct: 125 VKYLLENGANQSTATEDGFTPLAVAL--QQGHNQAVAILLENDTKGKVRLPALHIAARKD 182
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
T A+ A M VN + G+T + A H+ + +L+ +GA +
Sbjct: 183 DTK-SAALLLQNDHNADIQSKMMVN--RTTESGFTPLHIAAHYGNVNVATLLLNRGAAVD 239
Query: 208 EVDKSNRTLLEIANCHDHQVIIEIL 232
++ T L +A+ + ++++L
Sbjct: 240 FTARNGITPLHVASKRGNTNMVKLL 264
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARL 206
G TPL + G+V VA LL+ + + G+T + A + ++ ++L+++ A
Sbjct: 509 GYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA 568
Query: 207 TEVDKSNRTLLEIANCHDHQ-VIIEILKKSLNLDDDHKTDENSY 249
K+ T L +A +D+Q V + +L+K + H T +N Y
Sbjct: 569 DSAGKNGLTPLHVAAHYDNQKVALLLLEKGAS---PHATAKNGY 609
Score = 35.1 bits (77), Expect = 0.39
Identities = 52/226 (23%), Positives = 91/226 (40%), Gaps = 14/226 (6%)
Query: 30 DYSSQISSKKKVEVA-LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQ 88
D QI +K + + L A +G+ + VE L+ A K +G +PL A
Sbjct: 266 DRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTK--NGLSPLHMAAQGDH 323
Query: 89 DKIVQYLLEKDA---DPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDR 145
+ V++LL+ A D L + + A C + Y + L+D+ N
Sbjct: 324 VECVKHLLQHKAPVDDVTLDYLTALHVAAHCGH--------YRVTKLLLDKRANPNARAL 375
Query: 146 YGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGAR 205
G TPL A R+ V + L+ +I+ + G T + A I+ +L++ GA
Sbjct: 376 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 435
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLN 251
+ T L +A ++ L ++ L D +E + L+
Sbjct: 436 PDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLH 481
Score = 33.1 bits (72), Expect = 1.6
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 2/52 (3%)
Query: 52 GNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
GN+K V L+ N N K +G+TPL A I+ LL+ A PN
Sbjct: 718 GNVKMVNFLLKQGA--NVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPN 767
Score = 32.7 bits (71), Expect = 2.1
Identities = 18/83 (21%), Positives = 39/83 (46%)
Query: 152 MRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDK 211
+RA +G + + L ++I +Q+G A+ A +++ L+ +G+ + K
Sbjct: 15 LRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATK 74
Query: 212 SNRTLLEIANCHDHQVIIEILKK 234
T L IA+ ++++L K
Sbjct: 75 KGNTALHIASLAGQAEVVKVLVK 97
Score = 30.7 bits (66), Expect = 8.3
Identities = 30/134 (22%), Positives = 52/134 (38%), Gaps = 9/134 (6%)
Query: 129 IVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAV 188
+V L+ +N + G TPL A + V + LL+ N + G+T + A+
Sbjct: 91 VVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVAL 150
Query: 189 HHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENS 248
+ + +L+E + K L IA D + +L L +DH D S
Sbjct: 151 QQGHNQAVAILLENDTK----GKVRLPALHIAARKD-----DTKSAALLLQNDHNADIQS 201
Query: 249 YLNHQLTSWQDYYP 262
+ T+ + P
Sbjct: 202 KMMVNRTTESGFTP 215
>AK074570-1|BAC11066.1| 239|Homo sapiens protein ( Homo sapiens
cDNA FLJ90089 fis, clone HEMBA1005267, weakly similar to
ANKYRIN, BRAIN VARIANT 1. ).
Length = 239
Score = 56.0 bits (129), Expect = 2e-07
Identities = 33/108 (30%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L+ R C LN+ DR +TPL++A+ + A A LL + + D G TA+ +AV++
Sbjct: 72 LVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGADPNITDFFGRTALHYAVYNED 131
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIE-ILKKSLNLD 239
++E L+ G + E K+ L +A ++E +LKK N++
Sbjct: 132 TSMIEKLLSHGTNIEECSKNEYQPLLLAVSRRKVKMVEFLLKKKANVN 179
Score = 52.8 bits (121), Expect = 2e-06
Identities = 44/196 (22%), Positives = 94/196 (47%), Gaps = 10/196 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
+ A++ GN++ ++ L+ N + + T L AC Q ++V L+ + + NL
Sbjct: 24 IHRAVLRGNLEKLKYLLLTYYDANKRDRKER--TALHLACATGQPEMVHLLVSRRCELNL 81
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ TP++ A T+ L+ NI D +G+T L A+ + ++
Sbjct: 82 CDREDRTPLIKAVQLRQEACATL------LLQNGADPNITDFFGRTALHYAVYNEDTSMI 135
Query: 164 QKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIA-NC 222
+KLL NIE ++ + + AV + +++E L++K A + +D R+ L +A
Sbjct: 136 EKLLSHGTNIEECSKNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTL 195
Query: 223 HDHQVIIEILKKSLNL 238
+ ++I +L+ ++++
Sbjct: 196 GEKDIVILLLQHNIDV 211
Score = 41.9 bits (94), Expect = 0.003
Identities = 44/190 (23%), Positives = 85/190 (44%), Gaps = 7/190 (3%)
Query: 39 KKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEK 98
+K AL A G + V L++ + N + D TPL+ A Q+ LL+
Sbjct: 51 RKERTALHLACATGQPEMVHLLVSRRCELNLCDREDR--TPLIKAVQLRQEACATLLLQN 108
Query: 99 DADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSG 158
ADPN+ +D A + + DT S++ L+ + + PL+ A+S
Sbjct: 109 GADPNI-TDFFG--RTALHYAVYNEDT--SMIEKLLSHGTNIEECSKNEYQPLLLAVSRR 163
Query: 159 RVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLE 218
+V + + LL + N+ D G +A+ AV + +I+ +L++ + D + +
Sbjct: 164 KVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHNIDVFSRDVYGKLAED 223
Query: 219 IANCHDHQVI 228
A+ +++V+
Sbjct: 224 YASEAENRVV 233
>D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein.
Length = 1180
Score = 55.6 bits (128), Expect = 3e-07
Identities = 44/185 (23%), Positives = 84/185 (45%), Gaps = 5/185 (2%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N N +G+TPL HA + +V+ LL DA N+ S P+ A A I
Sbjct: 118 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQ---I 174
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ + + +N + +T L A G V + LL+ + MR+ T +
Sbjct: 175 VRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDL 234
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDE 246
A + + E+++ML+ L + T L +A + H+ ++++L + +D +++T+
Sbjct: 235 AALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDA-GMDSNYQTEM 293
Query: 247 NSYLN 251
S L+
Sbjct: 294 GSALH 298
>BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 55.6 bits (128), Expect = 3e-07
Identities = 44/185 (23%), Positives = 84/185 (45%), Gaps = 5/185 (2%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N N +G+TPL HA + +V+ LL DA N+ S P+ A A I
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQ---I 128
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ + + +N + +T L A G V + LL+ + MR+ T +
Sbjct: 129 VRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDL 188
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDE 246
A + + E+++ML+ L + T L +A + H+ ++++L + +D +++T+
Sbjct: 189 AALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDA-GMDSNYQTEM 247
Query: 247 NSYLN 251
S L+
Sbjct: 248 GSALH 252
>BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for
IMAGE:4618556) protein.
Length = 472
Score = 55.6 bits (128), Expect = 3e-07
Identities = 44/185 (23%), Positives = 84/185 (45%), Gaps = 5/185 (2%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N N +G+TPL HA + +V+ LL DA N+ S P+ A A I
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQ---I 128
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ + + +N + +T L A G V + LL+ + MR+ T +
Sbjct: 129 VRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDL 188
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDE 246
A + + E+++ML+ L + T L +A + H+ ++++L + +D +++T+
Sbjct: 189 AALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDA-GMDSNYQTEM 247
Query: 247 NSYLN 251
S L+
Sbjct: 248 GSALH 252
>AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 55.6 bits (128), Expect = 3e-07
Identities = 44/185 (23%), Positives = 84/185 (45%), Gaps = 5/185 (2%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N N +G+TPL HA + +V+ LL DA N+ S P+ A A I
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQ---I 128
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ + + +N + +T L A G V + LL+ + MR+ T +
Sbjct: 129 VRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDL 188
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDE 246
A + + E+++ML+ L + T L +A + H+ ++++L + +D +++T+
Sbjct: 189 AALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDA-GMDSNYQTEM 247
Query: 247 NSYLN 251
S L+
Sbjct: 248 GSALH 252
>AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 55.6 bits (128), Expect = 3e-07
Identities = 44/185 (23%), Positives = 84/185 (45%), Gaps = 5/185 (2%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N N +G+TPL HA + +V+ LL DA N+ S P+ A A I
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQ---I 128
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ + + +N + +T L A G V + LL+ + MR+ T +
Sbjct: 129 VRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDL 188
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDE 246
A + + E+++ML+ L + T L +A + H+ ++++L + +D +++T+
Sbjct: 189 AALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDA-GMDSNYQTEM 247
Query: 247 NSYLN 251
S L+
Sbjct: 248 GSALH 252
>AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 55.6 bits (128), Expect = 3e-07
Identities = 44/185 (23%), Positives = 84/185 (45%), Gaps = 5/185 (2%)
Query: 68 NANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL-HSDSVTPIMAACSNSSADNDTI 126
N N +G+TPL HA + +V+ LL DA N+ S P+ A A I
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQ---I 128
Query: 127 YSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFW 186
++ + + +N + +T L A G V + LL+ + MR+ T +
Sbjct: 129 VRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDL 188
Query: 187 AVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDE 246
A + + E+++ML+ L + T L +A + H+ ++++L + +D +++T+
Sbjct: 189 AALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDA-GMDSNYQTEM 247
Query: 247 NSYLN 251
S L+
Sbjct: 248 GSALH 252
>BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a
protein.
Length = 1065
Score = 54.8 bits (126), Expect = 4e-07
Identities = 46/193 (23%), Positives = 92/193 (47%), Gaps = 13/193 (6%)
Query: 44 ALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPN 103
AL A ++G++ V+ L+ N + +A + TPL AC ++Q L++ A +
Sbjct: 360 ALHAAALSGHVSTVKLLLENNAQVDATDVMKH--TPLFRACEMGHKDVIQTLIKGGARVD 417
Query: 104 L-HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCIL-NIGDRYGQTPLMRAISSGRVA 161
L D + + A +AD VC ++ N I N+ D G+TPL A G +
Sbjct: 418 LVDQDGHSLLHWAALGGNAD-------VCQILIENKINPNVQDYAGRTPLQCAAYGGYIN 470
Query: 162 VAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNR--TLLEI 219
L++ + ++DQ G TA+ W+ ++ + +++L++ A +++ + T L+
Sbjct: 471 CMAVLMENNADPNIQDQEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDY 530
Query: 220 ANCHDHQVIIEIL 232
A + +I+ +
Sbjct: 531 ALLGERHEVIQFM 543
Score = 52.4 bits (120), Expect = 2e-06
Identities = 51/207 (24%), Positives = 92/207 (44%), Gaps = 8/207 (3%)
Query: 28 NYDYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDS-GWTPLMHAC-F 85
+Y+ + S L A + G+ + V L+ E + I DS G TPL +A
Sbjct: 242 SYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL--ERNKSGTIPSDSQGATPLHYAAQS 299
Query: 86 HAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDR 145
+ + + +L + + T M A S +D + +++ D + +N+ D+
Sbjct: 300 NFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGS--DDVLRTMLSLKSDID--INMADK 355
Query: 146 YGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGAR 205
YG T L A SG V+ + LL+ ++ D T +F A ++++ LI+ GAR
Sbjct: 356 YGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGAR 415
Query: 206 LTEVDKSNRTLLEIANCHDHQVIIEIL 232
+ VD+ +LL A + + +IL
Sbjct: 416 VDLVDQDGHSLLHWAALGGNADVCQIL 442
Score = 41.9 bits (94), Expect = 0.003
Identities = 27/129 (20%), Positives = 53/129 (41%), Gaps = 3/129 (2%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
++ + + + D++G+TPLM + + R+ A LL ++ D TA+ A
Sbjct: 34 IVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGN 93
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNH 252
+++L+ + A + D T L + H + +L K + + D+N
Sbjct: 94 YRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKN---KQ 150
Query: 253 QLTSWQDYY 261
W YY
Sbjct: 151 TALHWSAYY 159
Score = 41.1 bits (92), Expect = 0.006
Identities = 39/169 (23%), Positives = 74/169 (43%), Gaps = 7/169 (4%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNL--I 134
T L + ++ + V+ L++ D++ + + P+ A ++ D ++++ C L
Sbjct: 151 TALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHK--DPSAVHTVRCILDAA 208
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP 193
+LN D G+TPL A++ G V V L + NI D T + WA
Sbjct: 209 PTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHA 268
Query: 194 EILEMLIEKGARLT-EVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDD 241
+I+ +L+E+ T D T L A + +++ K ++ DD
Sbjct: 269 QIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDD 317
Score = 35.1 bits (77), Expect = 0.39
Identities = 52/219 (23%), Positives = 87/219 (39%), Gaps = 26/219 (11%)
Query: 48 AIINGNMKDVEDLI--NNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL- 104
A +NG+ ++ LI N+ LK+ + G TPLM+ + LL+ AD N
Sbjct: 21 AAVNGDKGALQRLIVGNSALKDKED---QFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
HS +AA + Y + L+ R D TPL
Sbjct: 78 DHSQRTALHLAAQKGN-------YRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCL 130
Query: 164 QKLLDMQV--NIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIAN 221
LL ++ +D++ TA+ W+ ++N PE +++LI+ + + D + L A
Sbjct: 131 ALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAA 190
Query: 222 CHDHQVIIEILKKSLNLDDDHKTDENSYLNHQLTSWQDY 260
H + ++ L D T+ L +WQDY
Sbjct: 191 NHKDPSAVHTVRCIL---DAAPTE-------SLLNWQDY 219
>BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 23
protein.
Length = 305
Score = 54.8 bits (126), Expect = 4e-07
Identities = 42/158 (26%), Positives = 66/158 (41%), Gaps = 7/158 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLI 134
G + A Q+ ++ L DPN H T + AC + +V L+
Sbjct: 111 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQ------LVNKLL 164
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ D +TP+ A G + + ++LL+ + RD+ G T + AV P+
Sbjct: 165 VAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPD 224
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
LE LIE GA L DK T L A H +++L
Sbjct: 225 CLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 262
>AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat
protein 3 protein.
Length = 305
Score = 54.8 bits (126), Expect = 4e-07
Identities = 42/158 (26%), Positives = 66/158 (41%), Gaps = 7/158 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLI 134
G + A Q+ ++ L DPN H T + AC + +V L+
Sbjct: 111 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQ------LVNKLL 164
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ D +TP+ A G + + ++LL+ + RD+ G T + AV P+
Sbjct: 165 VAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPD 224
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
LE LIE GA L DK T L A H +++L
Sbjct: 225 CLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 262
>AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase 2
protein.
Length = 1166
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 83/195 (42%), Gaps = 18/195 (9%)
Query: 58 EDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMA 114
+D++ L+N AN++ D G PL +AC ++V LL ADPN + + TP+
Sbjct: 71 KDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHE 130
Query: 115 ACSNSSAD--------------NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
A D +T +L D + + Y + L+ + SG
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNE 190
Query: 161 AVAQKLLD-MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
LL + VN D T + A +N+ +I+++L++ GA + DK + L
Sbjct: 191 EKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHN 250
Query: 220 ANCHDHQVIIEILKK 234
A + H + E+L K
Sbjct: 251 ACSYGHYEVTELLVK 265
Score = 46.4 bits (105), Expect = 2e-04
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA NG+++ V+ L+ E K N+ TPL A + +V+YLL+ A+
Sbjct: 28 LFEACRNGDVERVKRLVTPE-KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQA 86
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
D + P+ ACS A+ +V L+ N D + TPL A G++ V
Sbjct: 87 RDDGGLIPLHNACSFGHAE------VVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVC 140
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL +R+ G TA+
Sbjct: 141 IVLLQHGAEPTIRNTDGRTAL 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 17/180 (9%)
Query: 57 VEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
VE ++ +E K NA L G T L A + + + LL DPN+ S +
Sbjct: 416 VEVVVKHEAKVNALDNL--GQTSLHRAAYCGHLQTCRLLLSYGCDPNIIS------LQGF 467
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ N+ + ++ I ++G+ L+ A +G V +KL +Q ++ R
Sbjct: 468 TALQMGNENVQQLLQEGI------SLGNSEADRQLLEAAKAGDVETVKKLCTVQ-SVNCR 520
Query: 177 DQHGW--TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
D G T + +A +N+ ++E L++ GA + DK L A + H + E+L K
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVK 580
Score = 42.3 bits (95), Expect = 0.003
Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 8/139 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA G+++ V+ L + N +I+ TPL A + + +V+YLL+ AD +
Sbjct: 496 LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYLLQHGADVHA 554
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ ++N+ D + TPL A + G+ +
Sbjct: 555 KDKGGLVPLHNACSYGH------YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEIC 608
Query: 164 QKLLDMQVNIEMRDQHGWT 182
+ LL + +++ G T
Sbjct: 609 KLLLQHGADPTKKNRDGNT 627
Score = 41.9 bits (94), Expect = 0.003
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGW--TPLMHACFHA 87
D + I + + AL +A G + V+ L + + N N + G TPL A +
Sbjct: 634 DGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPD---NVNCRDTQGRHSTPLHLAAGYN 690
Query: 88 QDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRY 146
++ +YLL+ AD N + P+ A S D + LI N +N D++
Sbjct: 691 NLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVD------VAALLIKYNACVNATDKW 744
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
TPL A GR + LL + +++Q G T
Sbjct: 745 AFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQT 780
Score = 39.1 bits (87), Expect = 0.024
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L E+ +GN + + L+ L N + TPL A + + KIVQ LL+ AD +
Sbjct: 181 LLESARSGNEEKMMALLT-PLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHA 239
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ +N D + TPL A S RV V
Sbjct: 240 KDKGDLVPLHNACSYGH------YEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVC 293
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL + + + H +A+
Sbjct: 294 SLLLSYGADPTLLNCHNKSAI 314
Score = 38.3 bits (85), Expect = 0.041
Identities = 25/100 (25%), Positives = 47/100 (47%)
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
S+V L+ ++ D+ G PL A S G VA+ L+ + + D +T + A
Sbjct: 540 SVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEA 599
Query: 188 VHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
+ EI ++L++ GA T+ ++ T L++ D +
Sbjct: 600 AAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI 639
Score = 36.3 bits (80), Expect = 0.17
Identities = 40/153 (26%), Positives = 72/153 (47%), Gaps = 14/153 (9%)
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+I + LL K A+ N + + +TP+ A + A ND + +V + N + D GQ
Sbjct: 381 QICELLLRKGANINEKTKEFLTPLHVA--SEKAHNDVVEVVVKHEAKVNAL----DNLGQ 434
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T L RA G + + LL + + G+TA+ E ++ L+++G L
Sbjct: 435 TSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTAL-----QMGNENVQQLLQEGISLGN 489
Query: 209 VDKSNRTLLEIANCHDHQVIIEILK-KSLNLDD 240
+++R LLE A D + + ++ +S+N D
Sbjct: 490 -SEADRQLLEAAKAGDVETVKKLCTVQSVNCRD 521
Score = 34.3 bits (75), Expect = 0.68
Identities = 23/72 (31%), Positives = 31/72 (43%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A GR V + LL N++ RD G + A E++ +L+ GA
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 209 VDKSNRTLLEIA 220
D N T L A
Sbjct: 120 RDNWNYTPLHEA 131
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 151 LMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP---EILEMLIEKGARL 206
L++A V +K L ++ VN + H TA+ A P +I E+L+ KGA +
Sbjct: 335 LLQAAREADVTRIKKHLSLEMVNFKHPQTHE-TALHCAAASPYPKRKQICELLLRKGANI 393
Query: 207 TEVDKSNRTLLEIANCHDHQVIIEILKK 234
E K T L +A+ H ++E++ K
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVK 421
>AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containing
protein protein.
Length = 296
Score = 54.8 bits (126), Expect = 4e-07
Identities = 42/158 (26%), Positives = 66/158 (41%), Gaps = 7/158 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLI 134
G + A Q+ ++ L DPN H T + AC + +V L+
Sbjct: 102 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQ------LVNKLL 155
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ D +TP+ A G + + ++LL+ + RD+ G T + AV P+
Sbjct: 156 VAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPD 215
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
LE LIE GA L DK T L A H +++L
Sbjct: 216 CLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 253
>AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyrin
repeat protein protein.
Length = 305
Score = 54.8 bits (126), Expect = 4e-07
Identities = 42/158 (26%), Positives = 66/158 (41%), Gaps = 7/158 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLI 134
G + A Q+ ++ L DPN H T + AC + +V L+
Sbjct: 111 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQ------LVNKLL 164
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ D +TP+ A G + + ++LL+ + RD+ G T + AV P+
Sbjct: 165 VAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPD 224
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
LE LIE GA L DK T L A H +++L
Sbjct: 225 CLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 262
>AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein.
Length = 1166
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 83/195 (42%), Gaps = 18/195 (9%)
Query: 58 EDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMA 114
+D++ L+N AN++ D G PL +AC ++V LL ADPN + + TP+
Sbjct: 71 KDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHE 130
Query: 115 ACSNSSAD--------------NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
A D +T +L D + + Y + L+ + SG
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNE 190
Query: 161 AVAQKLLD-MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
LL + VN D T + A +N+ +I+++L++ GA + DK + L
Sbjct: 191 EKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHN 250
Query: 220 ANCHDHQVIIEILKK 234
A + H + E+L K
Sbjct: 251 ACSYGHYEVTELLVK 265
Score = 46.4 bits (105), Expect = 2e-04
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA NG+++ V+ L+ E K N+ TPL A + +V+YLL+ A+
Sbjct: 28 LFEACRNGDVERVKRLVTPE-KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQA 86
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
D + P+ ACS A+ +V L+ N D + TPL A G++ V
Sbjct: 87 RDDGGLIPLHNACSFGHAE------VVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVC 140
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL +R+ G TA+
Sbjct: 141 IVLLQHGAEPTIRNTDGRTAL 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 17/180 (9%)
Query: 57 VEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
VE ++ +E K NA L G T L A + + + LL DPN+ S +
Sbjct: 416 VEVVVKHEAKVNALDNL--GQTSLHRAAYCGHLQTCRLLLSYGCDPNIIS------LQGF 467
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ N+ + ++ I ++G+ L+ A +G V +KL +Q ++ R
Sbjct: 468 TALQMGNENVQQLLQEGI------SLGNSEADRQLLEAAKAGDVETVKKLCTVQ-SVNCR 520
Query: 177 DQHGW--TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
D G T + +A +N+ ++E L++ GA + DK L A + H + E+L K
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVK 580
Score = 42.3 bits (95), Expect = 0.003
Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 8/139 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA G+++ V+ L + N +I+ TPL A + + +V+YLL+ AD +
Sbjct: 496 LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYLLQHGADVHA 554
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ ++N+ D + TPL A + G+ +
Sbjct: 555 KDKGGLVPLHNACSYGH------YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEIC 608
Query: 164 QKLLDMQVNIEMRDQHGWT 182
+ LL + +++ G T
Sbjct: 609 KLLLQHGADPTKKNRDGNT 627
Score = 41.9 bits (94), Expect = 0.003
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGW--TPLMHACFHA 87
D + I + + AL +A G + V+ L + + N N + G TPL A +
Sbjct: 634 DGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPD---NVNCRDTQGRHSTPLHLAAGYN 690
Query: 88 QDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRY 146
++ +YLL+ AD N + P+ A S D + LI N +N D++
Sbjct: 691 NLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVD------VAALLIKYNACVNATDKW 744
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
TPL A GR + LL + +++Q G T
Sbjct: 745 AFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQT 780
Score = 39.1 bits (87), Expect = 0.024
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L E+ +GN + + L+ L N + TPL A + + KIVQ LL+ AD +
Sbjct: 181 LLESARSGNEEKMMALLT-PLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHA 239
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ +N D + TPL A S RV V
Sbjct: 240 KDKGDLVPLHNACSYGH------YEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVC 293
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL + + + H +A+
Sbjct: 294 SLLLSYGADPTLLNCHNKSAI 314
Score = 38.3 bits (85), Expect = 0.041
Identities = 25/100 (25%), Positives = 47/100 (47%)
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
S+V L+ ++ D+ G PL A S G VA+ L+ + + D +T + A
Sbjct: 540 SVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEA 599
Query: 188 VHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
+ EI ++L++ GA T+ ++ T L++ D +
Sbjct: 600 AAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI 639
Score = 36.3 bits (80), Expect = 0.17
Identities = 40/153 (26%), Positives = 72/153 (47%), Gaps = 14/153 (9%)
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+I + LL K A+ N + + +TP+ A + A ND + +V + N + D GQ
Sbjct: 381 QICELLLRKGANINEKTKEFLTPLHVA--SEKAHNDVVEVVVKHEAKVNAL----DNLGQ 434
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T L RA G + + LL + + G+TA+ E ++ L+++G L
Sbjct: 435 TSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTAL-----QMGNENVQQLLQEGISLGN 489
Query: 209 VDKSNRTLLEIANCHDHQVIIEILK-KSLNLDD 240
+++R LLE A D + + ++ +S+N D
Sbjct: 490 -SEADRQLLEAAKAGDVETVKKLCTVQSVNCRD 521
Score = 34.3 bits (75), Expect = 0.68
Identities = 23/72 (31%), Positives = 31/72 (43%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A GR V + LL N++ RD G + A E++ +L+ GA
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 209 VDKSNRTLLEIA 220
D N T L A
Sbjct: 120 RDNWNYTPLHEA 131
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 151 LMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP---EILEMLIEKGARL 206
L++A V +K L ++ VN + H TA+ A P +I E+L+ KGA +
Sbjct: 335 LLQAAREADVTRIKKHLSLEMVNFKHPQTHE-TALHCAAASPYPKRKQICELLLRKGANI 393
Query: 207 TEVDKSNRTLLEIANCHDHQVIIEILKK 234
E K T L +A+ H ++E++ K
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVK 421
>AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 83/195 (42%), Gaps = 18/195 (9%)
Query: 58 EDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMA 114
+D++ L+N AN++ D G PL +AC ++V LL ADPN + + TP+
Sbjct: 71 KDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHE 130
Query: 115 ACSNSSAD--------------NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
A D +T +L D + + Y + L+ + SG
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNE 190
Query: 161 AVAQKLLD-MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
LL + VN D T + A +N+ +I+++L++ GA + DK + L
Sbjct: 191 EKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHN 250
Query: 220 ANCHDHQVIIEILKK 234
A + H + E+L K
Sbjct: 251 ACSYGHYEVTELLVK 265
Score = 46.4 bits (105), Expect = 2e-04
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA NG+++ V+ L+ E K N+ TPL A + +V+YLL+ A+
Sbjct: 28 LFEACRNGDVERVKRLVTPE-KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQA 86
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
D + P+ ACS A+ +V L+ N D + TPL A G++ V
Sbjct: 87 RDDGGLIPLHNACSFGHAE------VVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVC 140
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL +R+ G TA+
Sbjct: 141 IVLLQHGAEPTIRNTDGRTAL 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 17/180 (9%)
Query: 57 VEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
VE ++ +E K NA L G T L A + + + LL DPN+ S +
Sbjct: 416 VEVVVKHEAKVNALDNL--GQTSLHRAAYCGHLQTCRLLLSYGCDPNIIS------LQGF 467
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ N+ + ++ I ++G+ L+ A +G V +KL +Q ++ R
Sbjct: 468 TALQMGNENVQQLLQEGI------SLGNSEADRQLLEAAKAGDVETVKKLCTVQ-SVNCR 520
Query: 177 DQHGW--TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
D G T + +A +N+ ++E L++ GA + DK L A + H + E+L K
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVK 580
Score = 42.3 bits (95), Expect = 0.003
Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 8/139 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA G+++ V+ L + N +I+ TPL A + + +V+YLL+ AD +
Sbjct: 496 LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYLLQHGADVHA 554
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ ++N+ D + TPL A + G+ +
Sbjct: 555 KDKGGLVPLHNACSYGH------YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEIC 608
Query: 164 QKLLDMQVNIEMRDQHGWT 182
+ LL + +++ G T
Sbjct: 609 KLLLQHGADPTKKNRDGNT 627
Score = 41.9 bits (94), Expect = 0.003
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGW--TPLMHACFHA 87
D + I + + AL +A G + V+ L + + N N + G TPL A +
Sbjct: 634 DGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPD---NVNCRDTQGRHSTPLHLAAGYN 690
Query: 88 QDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRY 146
++ +YLL+ AD N + P+ A S D + LI N +N D++
Sbjct: 691 NLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVD------VAALLIKYNACVNATDKW 744
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
TPL A GR + LL + +++Q G T
Sbjct: 745 AFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQT 780
Score = 39.1 bits (87), Expect = 0.024
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L E+ +GN + + L+ L N + TPL A + + KIVQ LL+ AD +
Sbjct: 181 LLESARSGNEEKMMALLT-PLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHA 239
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ +N D + TPL A S RV V
Sbjct: 240 KDKGDLVPLHNACSYGH------YEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVC 293
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL + + + H +A+
Sbjct: 294 SLLLSYGADPTLLNCHNKSAI 314
Score = 38.3 bits (85), Expect = 0.041
Identities = 25/100 (25%), Positives = 47/100 (47%)
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
S+V L+ ++ D+ G PL A S G VA+ L+ + + D +T + A
Sbjct: 540 SVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEA 599
Query: 188 VHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
+ EI ++L++ GA T+ ++ T L++ D +
Sbjct: 600 AAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI 639
Score = 36.3 bits (80), Expect = 0.17
Identities = 40/153 (26%), Positives = 72/153 (47%), Gaps = 14/153 (9%)
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+I + LL K A+ N + + +TP+ A + A ND + +V + N + D GQ
Sbjct: 381 QICELLLRKGANINEKTKEFLTPLHVA--SEKAHNDVVEVVVKHEAKVNAL----DNLGQ 434
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T L RA G + + LL + + G+TA+ E ++ L+++G L
Sbjct: 435 TSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTAL-----QMGNENVQQLLQEGISLGN 489
Query: 209 VDKSNRTLLEIANCHDHQVIIEILK-KSLNLDD 240
+++R LLE A D + + ++ +S+N D
Sbjct: 490 -SEADRQLLEAAKAGDVETVKKLCTVQSVNCRD 521
Score = 34.3 bits (75), Expect = 0.68
Identities = 23/72 (31%), Positives = 31/72 (43%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A GR V + LL N++ RD G + A E++ +L+ GA
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 209 VDKSNRTLLEIA 220
D N T L A
Sbjct: 120 RDNWNYTPLHEA 131
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 151 LMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP---EILEMLIEKGARL 206
L++A V +K L ++ VN + H TA+ A P +I E+L+ KGA +
Sbjct: 335 LLQAAREADVTRIKKHLSLEMVNFKHPQTHE-TALHCAAASPYPKRKQICELLLRKGANI 393
Query: 207 TEVDKSNRTLLEIANCHDHQVIIEILKK 234
E K T L +A+ H ++E++ K
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVK 421
>AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 83/195 (42%), Gaps = 18/195 (9%)
Query: 58 EDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMA 114
+D++ L+N AN++ D G PL +AC ++V LL ADPN + + TP+
Sbjct: 71 KDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHE 130
Query: 115 ACSNSSAD--------------NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
A D +T +L D + + Y + L+ + SG
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNE 190
Query: 161 AVAQKLLD-MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
LL + VN D T + A +N+ +I+++L++ GA + DK + L
Sbjct: 191 EKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHN 250
Query: 220 ANCHDHQVIIEILKK 234
A + H + E+L K
Sbjct: 251 ACSYGHYEVTELLVK 265
Score = 46.4 bits (105), Expect = 2e-04
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA NG+++ V+ L+ E K N+ TPL A + +V+YLL+ A+
Sbjct: 28 LFEACRNGDVERVKRLVTPE-KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQA 86
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
D + P+ ACS A+ +V L+ N D + TPL A G++ V
Sbjct: 87 RDDGGLIPLHNACSFGHAE------VVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVC 140
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL +R+ G TA+
Sbjct: 141 IVLLQHGAEPTIRNTDGRTAL 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 17/180 (9%)
Query: 57 VEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
VE ++ +E K NA L G T L A + + + LL DPN+ S +
Sbjct: 416 VEVVVKHEAKVNALDNL--GQTSLHRAAYCGHLQTCRLLLSYGCDPNIIS------LQGF 467
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ N+ + ++ I ++G+ L+ A +G V +KL +Q ++ R
Sbjct: 468 TALQMGNENVQQLLQEGI------SLGNSEADRQLLEAAKAGDVETVKKLCTVQ-SVNCR 520
Query: 177 DQHGW--TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
D G T + +A +N+ ++E L++ GA + DK L A + H + E+L K
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVK 580
Score = 42.3 bits (95), Expect = 0.003
Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 8/139 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA G+++ V+ L + N +I+ TPL A + + +V+YLL+ AD +
Sbjct: 496 LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYLLQHGADVHA 554
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ ++N+ D + TPL A + G+ +
Sbjct: 555 KDKGGLVPLHNACSYGH------YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEIC 608
Query: 164 QKLLDMQVNIEMRDQHGWT 182
+ LL + +++ G T
Sbjct: 609 KLLLQHGADPTKKNRDGNT 627
Score = 41.9 bits (94), Expect = 0.003
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGW--TPLMHACFHA 87
D + I + + AL +A G + V+ L + + N N + G TPL A +
Sbjct: 634 DGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPD---NVNCRDTQGRHSTPLHLAAGYN 690
Query: 88 QDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRY 146
++ +YLL+ AD N + P+ A S D + LI N +N D++
Sbjct: 691 NLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVD------VAALLIKYNACVNATDKW 744
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
TPL A GR + LL + +++Q G T
Sbjct: 745 AFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQT 780
Score = 39.1 bits (87), Expect = 0.024
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L E+ +GN + + L+ L N + TPL A + + KIVQ LL+ AD +
Sbjct: 181 LLESARSGNEEKMMALLT-PLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHA 239
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ +N D + TPL A S RV V
Sbjct: 240 KDKGDLVPLHNACSYGH------YEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVC 293
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL + + + H +A+
Sbjct: 294 SLLLSYGADPTLLNCHNKSAI 314
Score = 38.3 bits (85), Expect = 0.041
Identities = 25/100 (25%), Positives = 47/100 (47%)
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
S+V L+ ++ D+ G PL A S G VA+ L+ + + D +T + A
Sbjct: 540 SVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEA 599
Query: 188 VHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
+ EI ++L++ GA T+ ++ T L++ D +
Sbjct: 600 AAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI 639
Score = 36.3 bits (80), Expect = 0.17
Identities = 40/153 (26%), Positives = 72/153 (47%), Gaps = 14/153 (9%)
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+I + LL K A+ N + + +TP+ A + A ND + +V + N + D GQ
Sbjct: 381 QICELLLRKGANINEKTKEFLTPLHVA--SEKAHNDVVEVVVKHEAKVNAL----DNLGQ 434
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T L RA G + + LL + + G+TA+ E ++ L+++G L
Sbjct: 435 TSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTAL-----QMGNENVQQLLQEGISLGN 489
Query: 209 VDKSNRTLLEIANCHDHQVIIEILK-KSLNLDD 240
+++R LLE A D + + ++ +S+N D
Sbjct: 490 -SEADRQLLEAAKAGDVETVKKLCTVQSVNCRD 521
Score = 34.3 bits (75), Expect = 0.68
Identities = 23/72 (31%), Positives = 31/72 (43%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A GR V + LL N++ RD G + A E++ +L+ GA
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 209 VDKSNRTLLEIA 220
D N T L A
Sbjct: 120 RDNWNYTPLHEA 131
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 151 LMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP---EILEMLIEKGARL 206
L++A V +K L ++ VN + H TA+ A P +I E+L+ KGA +
Sbjct: 335 LLQAAREADVTRIKKHLSLEMVNFKHPQTHE-TALHCAAASPYPKRKQICELLLRKGANI 393
Query: 207 TEVDKSNRTLLEIANCHDHQVIIEILKK 234
E K T L +A+ H ++E++ K
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVK 421
>AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein.
Length = 1166
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 83/195 (42%), Gaps = 18/195 (9%)
Query: 58 EDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMA 114
+D++ L+N AN++ D G PL +AC ++V LL ADPN + + TP+
Sbjct: 71 KDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHE 130
Query: 115 ACSNSSAD--------------NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
A D +T +L D + + Y + L+ + SG
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNE 190
Query: 161 AVAQKLLD-MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
LL + VN D T + A +N+ +I+++L++ GA + DK + L
Sbjct: 191 EKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHN 250
Query: 220 ANCHDHQVIIEILKK 234
A + H + E+L K
Sbjct: 251 ACSYGHYEVTELLVK 265
Score = 46.4 bits (105), Expect = 2e-04
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA NG+++ V+ L+ E K N+ TPL A + +V+YLL+ A+
Sbjct: 28 LFEACRNGDVERVKRLVTPE-KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQA 86
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
D + P+ ACS A+ +V L+ N D + TPL A G++ V
Sbjct: 87 RDDGGLIPLHNACSFGHAE------VVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVC 140
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL +R+ G TA+
Sbjct: 141 IVLLQHGAEPTIRNTDGRTAL 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 17/180 (9%)
Query: 57 VEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
VE ++ +E K NA L G T L A + + + LL DPN+ S +
Sbjct: 416 VEVVVKHEAKVNALDNL--GQTSLHRAAYCGHLQTCRLLLSYGCDPNIIS------LQGF 467
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ N+ + ++ I ++G+ L+ A +G V +KL +Q ++ R
Sbjct: 468 TALQMGNENVQQLLQEGI------SLGNSEADRQLLEAAKAGDVETVKKLCTVQ-SVNCR 520
Query: 177 DQHGW--TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
D G T + +A +N+ ++E L++ GA + DK L A + H + E+L K
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVK 580
Score = 42.3 bits (95), Expect = 0.003
Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 8/139 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA G+++ V+ L + N +I+ TPL A + + +V+YLL+ AD +
Sbjct: 496 LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYLLQHGADVHA 554
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ ++N+ D + TPL A + G+ +
Sbjct: 555 KDKGGLVPLHNACSYGH------YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEIC 608
Query: 164 QKLLDMQVNIEMRDQHGWT 182
+ LL + +++ G T
Sbjct: 609 KLLLQHGADPTKKNRDGNT 627
Score = 41.9 bits (94), Expect = 0.003
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGW--TPLMHACFHA 87
D + I + + AL +A G + V+ L + + N N + G TPL A +
Sbjct: 634 DGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPD---NVNCRDTQGRHSTPLHLAAGYN 690
Query: 88 QDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRY 146
++ +YLL+ AD N + P+ A S D + LI N +N D++
Sbjct: 691 NLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVD------VAALLIKYNACVNATDKW 744
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
TPL A GR + LL + +++Q G T
Sbjct: 745 AFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQT 780
Score = 39.1 bits (87), Expect = 0.024
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L E+ +GN + + L+ L N + TPL A + + KIVQ LL+ AD +
Sbjct: 181 LLESARSGNEEKMMALLT-PLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHA 239
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ +N D + TPL A S RV V
Sbjct: 240 KDKGDLVPLHNACSYGH------YEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVC 293
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL + + + H +A+
Sbjct: 294 SLLLSYGADPTLLNCHNKSAI 314
Score = 38.3 bits (85), Expect = 0.041
Identities = 25/100 (25%), Positives = 47/100 (47%)
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
S+V L+ ++ D+ G PL A S G VA+ L+ + + D +T + A
Sbjct: 540 SVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEA 599
Query: 188 VHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
+ EI ++L++ GA T+ ++ T L++ D +
Sbjct: 600 AAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI 639
Score = 36.3 bits (80), Expect = 0.17
Identities = 40/153 (26%), Positives = 72/153 (47%), Gaps = 14/153 (9%)
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+I + LL K A+ N + + +TP+ A + A ND + +V + N + D GQ
Sbjct: 381 QICELLLRKGANINEKTKEFLTPLHVA--SEKAHNDVVEVVVKHEAKVNAL----DNLGQ 434
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T L RA G + + LL + + G+TA+ E ++ L+++G L
Sbjct: 435 TSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTAL-----QMGNENVQQLLQEGISLGN 489
Query: 209 VDKSNRTLLEIANCHDHQVIIEILK-KSLNLDD 240
+++R LLE A D + + ++ +S+N D
Sbjct: 490 -SEADRQLLEAAKAGDVETVKKLCTVQSVNCRD 521
Score = 34.3 bits (75), Expect = 0.68
Identities = 23/72 (31%), Positives = 31/72 (43%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A GR V + LL N++ RD G + A E++ +L+ GA
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 209 VDKSNRTLLEIA 220
D N T L A
Sbjct: 120 RDNWNYTPLHEA 131
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 151 LMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP---EILEMLIEKGARL 206
L++A V +K L ++ VN + H TA+ A P +I E+L+ KGA +
Sbjct: 335 LLQAAREADVTRIKKHLSLEMVNFKHPQTHE-TALHCAAASPYPKRKQICELLLRKGANI 393
Query: 207 TEVDKSNRTLLEIANCHDHQVIIEILKK 234
E K T L +A+ H ++E++ K
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVK 421
>AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related protein
protein.
Length = 1265
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 83/195 (42%), Gaps = 18/195 (9%)
Query: 58 EDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMA 114
+D++ L+N AN++ D G PL +AC ++V LL ADPN + + TP+
Sbjct: 171 KDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHE 230
Query: 115 ACSNSSAD--------------NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
A D +T +L D + + Y + L+ + SG
Sbjct: 231 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNE 290
Query: 161 AVAQKLLD-MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
LL + VN D T + A +N+ +I+++L++ GA + DK + L
Sbjct: 291 EKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHN 350
Query: 220 ANCHDHQVIIEILKK 234
A + H + E+L K
Sbjct: 351 ACSYGHYEVTELLVK 365
Score = 47.2 bits (107), Expect = 9e-05
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA NG+++ V+ L+ E K N+ TPL A + +V+YLL+ A+
Sbjct: 128 LFEACRNGDVERVKRLVTPE-KVNSRDTAGRKSTPLHFAAXFGRKDVVEYLLQNGANVQA 186
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
D + P+ ACS A+ +V L+ N D + TPL A G++ V
Sbjct: 187 RDDGGLIPLHNACSFGHAE------VVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVC 240
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL +R+ G TA+
Sbjct: 241 IVLLQHGAEPTIRNTDGRTAL 261
Score = 43.6 bits (98), Expect = 0.001
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 17/180 (9%)
Query: 57 VEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
VE ++ +E K NA L G T L A + + + LL DPN+ S +
Sbjct: 515 VEVVVKHEAKVNALDNL--GQTSLHRAAYCGHLQTCRLLLSYGCDPNIIS------LQGF 566
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ N+ + ++ I ++G+ L+ A +G V +KL +Q ++ R
Sbjct: 567 TALQMGNENVQQLLQEGI------SLGNSEADRQLLEAAKAGDVETVKKLCTVQ-SVNCR 619
Query: 177 DQHGW--TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
D G T + +A +N+ ++E L++ GA + DK L A + H + E+L K
Sbjct: 620 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVK 679
Score = 42.3 bits (95), Expect = 0.003
Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 8/139 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA G+++ V+ L + N +I+ TPL A + + +V+YLL+ AD +
Sbjct: 595 LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYLLQHGADVHA 653
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ ++N+ D + TPL A + G+ +
Sbjct: 654 KDKGGLVPLHNACSYGH------YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEIC 707
Query: 164 QKLLDMQVNIEMRDQHGWT 182
+ LL + +++ G T
Sbjct: 708 KLLLQHGADPTKKNRDGNT 726
Score = 41.9 bits (94), Expect = 0.003
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGW--TPLMHACFHA 87
D + I + + AL +A G + V+ L + + N N + G TPL A +
Sbjct: 733 DGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPD---NVNCRDTQGRHSTPLHLAAGYN 789
Query: 88 QDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRY 146
++ +YLL+ AD N + P+ A S D + LI N +N D++
Sbjct: 790 NLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVD------VAALLIKYNACVNATDKW 843
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
TPL A GR + LL + +++Q G T
Sbjct: 844 AFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQT 879
Score = 39.1 bits (87), Expect = 0.024
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L E+ +GN + + L+ L N + TPL A + + KIVQ LL+ AD +
Sbjct: 281 LLESARSGNEEKMMALLT-PLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHA 339
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ +N D + TPL A S RV V
Sbjct: 340 KDKGDLVPLHNACSYGH------YEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVC 393
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL + + + H +A+
Sbjct: 394 SLLLSYGADPTLLNCHNKSAI 414
Score = 38.3 bits (85), Expect = 0.041
Identities = 25/100 (25%), Positives = 47/100 (47%)
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
S+V L+ ++ D+ G PL A S G VA+ L+ + + D +T + A
Sbjct: 639 SVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEA 698
Query: 188 VHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
+ EI ++L++ GA T+ ++ T L++ D +
Sbjct: 699 AAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI 738
Score = 36.3 bits (80), Expect = 0.17
Identities = 40/153 (26%), Positives = 72/153 (47%), Gaps = 14/153 (9%)
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+I + LL K A+ N + + +TP+ A + A ND + +V + N + D GQ
Sbjct: 480 QICELLLRKGANINEKTKEFLTPLHVA--SEKAHNDVVEVVVKHEAKVNAL----DNLGQ 533
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T L RA G + + LL + + G+TA+ E ++ L+++G L
Sbjct: 534 TSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTAL-----QMGNENVQQLLQEGISLGN 588
Query: 209 VDKSNRTLLEIANCHDHQVIIEILK-KSLNLDD 240
+++R LLE A D + + ++ +S+N D
Sbjct: 589 -SEADRQLLEAAKAGDVETVKKLCTVQSVNCRD 620
Score = 35.1 bits (77), Expect = 0.39
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 148 QTPLMRAIS-SGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQP---EILEMLIEKG 203
Q PL+ A + V +K L +++ I+ H TA+ A P +I E+L+ KG
Sbjct: 431 QRPLVAAXAREADVTRIKKHLSLEMVIQASQTHE-TALHCAAASPYPKRKQICELLLRKG 489
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + E K T L +A+ H ++E++ K
Sbjct: 490 ANINEKTKEFLTPLHVASEKAHNDVVEVVVK 520
Score = 34.3 bits (75), Expect = 0.68
Identities = 23/72 (31%), Positives = 31/72 (43%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A GR V + LL N++ RD G + A E++ +L+ GA
Sbjct: 160 TPLHFAAXFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 219
Query: 209 VDKSNRTLLEIA 220
D N T L A
Sbjct: 220 RDNWNYTPLHEA 231
>AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein
protein.
Length = 1166
Score = 54.8 bits (126), Expect = 4e-07
Identities = 49/195 (25%), Positives = 83/195 (42%), Gaps = 18/195 (9%)
Query: 58 EDLINNELKNNANIKL--DSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMA 114
+D++ L+N AN++ D G PL +AC ++V LL ADPN + + TP+
Sbjct: 71 KDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHE 130
Query: 115 ACSNSSAD--------------NDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
A D +T +L D + + Y + L+ + SG
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNE 190
Query: 161 AVAQKLLD-MQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEI 219
LL + VN D T + A +N+ +I+++L++ GA + DK + L
Sbjct: 191 EKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHN 250
Query: 220 ANCHDHQVIIEILKK 234
A + H + E+L K
Sbjct: 251 ACSYGHYEVTELLVK 265
Score = 46.4 bits (105), Expect = 2e-04
Identities = 41/141 (29%), Positives = 63/141 (44%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA NG+++ V+ L+ E K N+ TPL A + +V+YLL+ A+
Sbjct: 28 LFEACRNGDVERVKRLVTPE-KVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQA 86
Query: 105 HSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
D + P+ ACS A+ +V L+ N D + TPL A G++ V
Sbjct: 87 RDDGGLIPLHNACSFGHAE------VVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVC 140
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL +R+ G TA+
Sbjct: 141 IVLLQHGAEPTIRNTDGRTAL 161
Score = 43.6 bits (98), Expect = 0.001
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 17/180 (9%)
Query: 57 VEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAAC 116
VE ++ +E K NA L G T L A + + + LL DPN+ S +
Sbjct: 416 VEVVVKHEAKVNALDNL--GQTSLHRAAYCGHLQTCRLLLSYGCDPNIIS------LQGF 467
Query: 117 SNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMR 176
+ N+ + ++ I ++G+ L+ A +G V +KL +Q ++ R
Sbjct: 468 TALQMGNENVQQLLQEGI------SLGNSEADRQLLEAAKAGDVETVKKLCTVQ-SVNCR 520
Query: 177 DQHGW--TAVFWAVHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
D G T + +A +N+ ++E L++ GA + DK L A + H + E+L K
Sbjct: 521 DIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVK 580
Score = 42.3 bits (95), Expect = 0.003
Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 8/139 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L EA G+++ V+ L + N +I+ TPL A + + +V+YLL+ AD +
Sbjct: 496 LLEAAKAGDVETVKKLCTVQSVNCRDIEGRQS-TPLHFAAGYNRVSVVEYLLQHGADVHA 554
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ ++N+ D + TPL A + G+ +
Sbjct: 555 KDKGGLVPLHNACSYGH------YEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEIC 608
Query: 164 QKLLDMQVNIEMRDQHGWT 182
+ LL + +++ G T
Sbjct: 609 KLLLQHGADPTKKNRDGNT 627
Score = 41.9 bits (94), Expect = 0.003
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 12/156 (7%)
Query: 30 DYSSQISSKKKVEVALQEAIINGNMKDVEDLINNELKNNANIKLDSGW--TPLMHACFHA 87
D + I + + AL +A G + V+ L + + N N + G TPL A +
Sbjct: 634 DGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPD---NVNCRDTQGRHSTPLHLAAGYN 690
Query: 88 QDKIVQYLLEKDADPNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRY 146
++ +YLL+ AD N + P+ A S D + LI N +N D++
Sbjct: 691 NLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVD------VAALLIKYNACVNATDKW 744
Query: 147 GQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWT 182
TPL A GR + LL + +++Q G T
Sbjct: 745 AFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQT 780
Score = 39.1 bits (87), Expect = 0.024
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 45 LQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDADPNL 104
L E+ +GN + + L+ L N + TPL A + + KIVQ LL+ AD +
Sbjct: 181 LLESARSGNEEKMMALLT-PLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHA 239
Query: 105 -HSDSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVA 163
+ P+ ACS Y + L+ +N D + TPL A S RV V
Sbjct: 240 KDKGDLVPLHNACSYGH------YEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVC 293
Query: 164 QKLLDMQVNIEMRDQHGWTAV 184
LL + + + H +A+
Sbjct: 294 SLLLSYGADPTLLNCHNKSAI 314
Score = 38.3 bits (85), Expect = 0.041
Identities = 25/100 (25%), Positives = 47/100 (47%)
Query: 128 SIVCNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWA 187
S+V L+ ++ D+ G PL A S G VA+ L+ + + D +T + A
Sbjct: 540 SVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEA 599
Query: 188 VHHNQPEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQV 227
+ EI ++L++ GA T+ ++ T L++ D +
Sbjct: 600 AAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI 639
Score = 36.3 bits (80), Expect = 0.17
Identities = 40/153 (26%), Positives = 72/153 (47%), Gaps = 14/153 (9%)
Query: 90 KIVQYLLEKDADPNLHS-DSVTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQ 148
+I + LL K A+ N + + +TP+ A + A ND + +V + N + D GQ
Sbjct: 381 QICELLLRKGANINEKTKEFLTPLHVA--SEKAHNDVVEVVVKHEAKVNAL----DNLGQ 434
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
T L RA G + + LL + + G+TA+ E ++ L+++G L
Sbjct: 435 TSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTAL-----QMGNENVQQLLQEGISLGN 489
Query: 209 VDKSNRTLLEIANCHDHQVIIEILK-KSLNLDD 240
+++R LLE A D + + ++ +S+N D
Sbjct: 490 -SEADRQLLEAAKAGDVETVKKLCTVQSVNCRD 521
Score = 34.3 bits (75), Expect = 0.68
Identities = 23/72 (31%), Positives = 31/72 (43%)
Query: 149 TPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTE 208
TPL A GR V + LL N++ RD G + A E++ +L+ GA
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 209 VDKSNRTLLEIA 220
D N T L A
Sbjct: 120 RDNWNYTPLHEA 131
Score = 33.1 bits (72), Expect = 1.6
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 151 LMRAISSGRVAVAQKLLDMQ-VNIEMRDQHGWTAVFWAVHHNQP---EILEMLIEKGARL 206
L++A V +K L ++ VN + H TA+ A P +I E+L+ KGA +
Sbjct: 335 LLQAAREADVTRIKKHLSLEMVNFKHPQTHE-TALHCAAASPYPKRKQICELLLRKGANI 393
Query: 207 TEVDKSNRTLLEIANCHDHQVIIEILKK 234
E K T L +A+ H ++E++ K
Sbjct: 394 NEKTKEFLTPLHVASEKAHNDVVEVVVK 421
>AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein.
Length = 305
Score = 54.8 bits (126), Expect = 4e-07
Identities = 42/158 (26%), Positives = 66/158 (41%), Gaps = 7/158 (4%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDADPNLHSD-SVTPIMAACSNSSADNDTIYSIVCNLI 134
G + A Q+ ++ L DPN H T + AC + +V L+
Sbjct: 111 GLEMFLKAAAENQEYLIDKYLTDGGDPNAHDKLHRTALHWACLKGHSQ------LVNKLL 164
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
++ D +TP+ A G + + ++LL+ + RD+ G T + AV P+
Sbjct: 165 VAGATVDARDLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPD 224
Query: 195 ILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
LE LIE GA L DK T L A H +++L
Sbjct: 225 CLEHLIECGAHLNAQDKEGDTALHEAVRHGSYKAMKLL 262
>U13048-1|AAA65710.1| 348|Homo sapiens nuclear respiratory factor-2
subunit gamma 2 protein.
Length = 348
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>U13047-1|AAA65709.1| 360|Homo sapiens nuclear respiratory factor-2
subunit gamma 1 protein.
Length = 360
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>U13046-1|AAA65708.1| 383|Homo sapiens nuclear respiratory factor-2
subunit beta 2 protein.
Length = 383
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>U13045-1|AAA65707.1| 395|Homo sapiens nuclear respiratory factor-2
subunit beta 1 protein.
Length = 395
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>D13317-1|BAA02574.1| 383|Homo sapiens transcription factor
E4TF1-53 protein.
Length = 383
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>D13316-1|BAA02573.1| 347|Homo sapiens transcription factor
E4TF1-47 protein.
Length = 347
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>BT006652-1|AAP35298.1| 360|Homo sapiens GA binding protein
transcription factor, beta subunit 2, 47kDa protein.
Length = 360
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 54.4 bits (125), Expect = 6e-07
Identities = 35/137 (25%), Positives = 59/137 (43%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L + +N+ D G PL+ A+ +G + LLD ++ R++ G TA+ A
Sbjct: 138 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGS 197
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNH 252
+E LI+KGA L VD L + ++ I +L ++ D D KT +
Sbjct: 198 SNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHD 257
Query: 253 QLTSWQDYYPGIEKNER 269
Q++ G K +
Sbjct: 258 QVSKISSERSGTPKKRK 274
Score = 34.7 bits (76), Expect = 0.51
Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 9/127 (7%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
+ AL A G ++ V+ L E K+ N+K G PL+ A + +I +LL+ AD
Sbjct: 120 KTALHYAAAQGCLQAVQILC--EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGAD 177
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
N + S T +M AC S+ + V LI + LN+ D G L + S
Sbjct: 178 VNSRNKSGRTALMLACEIGSS------NAVEALIKKGADLNLVDSLGYNALHYSKLSENA 231
Query: 161 AVAQKLL 167
+ LL
Sbjct: 232 GIQSLLL 238
>BC050702-1|AAH50702.1| 395|Homo sapiens GA binding protein
transcription factor, beta subunit 2 protein.
Length = 395
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>BC046186-1|AAH46186.1| 163|Homo sapiens ankyrin repeat domain 36
protein.
Length = 163
Score = 54.4 bits (125), Expect = 6e-07
Identities = 38/130 (29%), Positives = 61/130 (46%), Gaps = 7/130 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
A H + ++YLL D N T + AC+ + +V L+ R C LN
Sbjct: 39 AVLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPE------MVHLLVSRRCELN 92
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ DR +TPL++A+ + A A LL N + D G TA+ +AV++ ++E L+
Sbjct: 93 LCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLS 152
Query: 202 KGARLTEVDK 211
G + E K
Sbjct: 153 HGTNIEECSK 162
Score = 32.7 bits (71), Expect = 2.1
Identities = 19/65 (29%), Positives = 32/65 (49%)
Query: 153 RAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKS 212
RA+ G + + LL + RD+ TA+ A QPE++ +L+ + L D+
Sbjct: 38 RAVLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDRE 97
Query: 213 NRTLL 217
+RT L
Sbjct: 98 DRTPL 102
>BC036080-1|AAH36080.1| 383|Homo sapiens GA binding protein
transcription factor, beta subunit 2 protein.
Length = 383
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>BC016910-1|AAH16910.1| 360|Homo sapiens GA binding protein
transcription factor, beta subunit 2 protein.
Length = 360
Score = 54.4 bits (125), Expect = 6e-07
Identities = 27/86 (31%), Positives = 48/86 (55%)
Query: 148 QTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLT 207
+TPL A S G ++ + LL ++ +D TA+ WA HN E++E+LI+ GA +
Sbjct: 72 RTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVVELLIKYGADVH 131
Query: 208 EVDKSNRTLLEIANCHDHQVIIEILK 233
K +T +I+ + ++ + EIL+
Sbjct: 132 TQSKFCKTAFDISIDNGNEDLAEILQ 157
Score = 44.4 bits (100), Expect = 6e-04
Identities = 27/91 (29%), Positives = 43/91 (47%)
Query: 144 DRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKG 203
D G +PL A G + + LL V+ + R + T + A I+E+L++ G
Sbjct: 35 DWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHG 94
Query: 204 ARLTEVDKSNRTLLEIANCHDHQVIIEILKK 234
A + D T L A H+HQ ++E+L K
Sbjct: 95 ADVNAKDMLKMTALHWATEHNHQEVVELLIK 125
>AY462869-1|AAS58863.1| 498|Homo sapiens POTE8A protein.
Length = 498
Score = 54.4 bits (125), Expect = 6e-07
Identities = 38/162 (23%), Positives = 75/162 (46%), Gaps = 6/162 (3%)
Query: 78 TPLMHACFHAQDKIVQYLLEKDADPNLHSDSVTPIMAACSNSSADNDTIYSIVCNLIDRN 137
T L AC + ++V LL++ ++ + D + L+
Sbjct: 101 TALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALM-----LLQHG 155
Query: 138 CILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILE 197
N+ D YG T L A+ + +A+ LL +IE +++ G T + AVH + +++
Sbjct: 156 TDPNLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVK 215
Query: 198 MLIEKGARLTEVDKSNRTLLEIA-NCHDHQVIIEILKKSLNL 238
LI+K A L +D+ RT L +A C ++ +L++++++
Sbjct: 216 FLIKKKANLNALDRFGRTALILAVRCGSASIVSLLLQQNIDV 257
Score = 42.7 bits (96), Expect = 0.002
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 7/125 (5%)
Query: 76 GWTPLMHACFHAQDKIVQYLLEKDAD-PNLHSDSVTPIMAACSNSSADNDTIYSIVCNLI 134
G T L +A ++ + + LL AD + + +TP++ A +V LI
Sbjct: 165 GNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQ------RMVKFLI 218
Query: 135 DRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPE 194
+ LN DR+G+T L+ A+ G ++ LL +++ +D G TA +AV +
Sbjct: 219 KKKANLNALDRFGRTALILAVRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSI 278
Query: 195 ILEML 199
I ++L
Sbjct: 279 ICQLL 283
Score = 35.9 bits (79), Expect = 0.22
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 7/102 (6%)
Query: 72 KLDSGWTPLMHACFHAQDKIVQYLLEKDADPN-LHSDSVTPIMAACSNSSADNDTIYSIV 130
K G TPL+ A + ++V++L++K A+ N L T ++ A SA SIV
Sbjct: 194 KNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRFGRTALILAVRCGSA------SIV 247
Query: 131 CNLIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVN 172
L+ +N + D +GQT A+SS + Q L D + N
Sbjct: 248 SLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLLSDYKEN 289
Score = 35.1 bits (77), Expect = 0.39
Identities = 25/93 (26%), Positives = 42/93 (45%)
Query: 140 LNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEML 199
+N D+ +T L A ++G V LLD Q + + D TA+ AV + E ML
Sbjct: 92 INKRDKKKRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALML 151
Query: 200 IEKGARLTEVDKSNRTLLEIANCHDHQVIIEIL 232
++ G D T L A ++ +++ + L
Sbjct: 152 LQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTL 184
>AY358571-1|AAQ88934.1| 151|Homo sapiens ankyrin-related protein.
Length = 151
Score = 54.4 bits (125), Expect = 6e-07
Identities = 38/130 (29%), Positives = 61/130 (46%), Gaps = 7/130 (5%)
Query: 83 ACFHAQDKIVQYLLEKDADPNLHSDSV-TPIMAACSNSSADNDTIYSIVCNLIDRNCILN 141
A H + ++YLL D N T + AC+ + +V L+ R C LN
Sbjct: 27 AVLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPE------MVHLLVSRRCELN 80
Query: 142 IGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIE 201
+ DR +TPL++A+ + A A LL N + D G TA+ +AV++ ++E L+
Sbjct: 81 LCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLS 140
Query: 202 KGARLTEVDK 211
G + E K
Sbjct: 141 HGTNIEECSK 150
Score = 32.7 bits (71), Expect = 2.1
Identities = 19/65 (29%), Positives = 32/65 (49%)
Query: 153 RAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQPEILEMLIEKGARLTEVDKS 212
RA+ G + + LL + RD+ TA+ A QPE++ +L+ + L D+
Sbjct: 26 RAVLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDRE 85
Query: 213 NRTLL 217
+RT L
Sbjct: 86 DRTPL 90
>AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 14
isoform protein.
Length = 972
Score = 54.4 bits (125), Expect = 6e-07
Identities = 35/137 (25%), Positives = 59/137 (43%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L + +N+ D G PL+ A+ +G + LLD ++ R++ G TA+ A
Sbjct: 130 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGS 189
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNH 252
+E LI+KGA L VD L + ++ I +L ++ D D KT +
Sbjct: 190 SNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHD 249
Query: 253 QLTSWQDYYPGIEKNER 269
Q++ G K +
Sbjct: 250 QVSKISSERSGTPKTRK 266
Score = 34.7 bits (76), Expect = 0.51
Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 9/127 (7%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
+ AL A G ++ V+ L E K+ N+K G PL+ A + +I +LL+ AD
Sbjct: 112 KTALHYAAAQGCLQAVQILC--EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGAD 169
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
N + S T +M AC S+ + V LI + LN+ D G L + S
Sbjct: 170 VNSRNKSGRTALMLACEIGSS------NAVEALIKKGADLNLVDSLGYNALHYSKLSENA 223
Query: 161 AVAQKLL 167
+ LL
Sbjct: 224 GIQSLLL 230
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 54.4 bits (125), Expect = 6e-07
Identities = 35/137 (25%), Positives = 59/137 (43%)
Query: 133 LIDRNCILNIGDRYGQTPLMRAISSGRVAVAQKLLDMQVNIEMRDQHGWTAVFWAVHHNQ 192
L + +N+ D G PL+ A+ +G + LLD ++ R++ G TA+ A
Sbjct: 141 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGS 200
Query: 193 PEILEMLIEKGARLTEVDKSNRTLLEIANCHDHQVIIEILKKSLNLDDDHKTDENSYLNH 252
+E LI+KGA L VD L + ++ I +L ++ D D KT +
Sbjct: 201 SNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHD 260
Query: 253 QLTSWQDYYPGIEKNER 269
Q++ G K +
Sbjct: 261 QVSKISSERSGTPKKRK 277
Score = 34.7 bits (76), Expect = 0.51
Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 9/127 (7%)
Query: 42 EVALQEAIINGNMKDVEDLINNELKNNANIKLDSGWTPLMHACFHAQDKIVQYLLEKDAD 101
+ AL A G ++ V+ L E K+ N+K G PL+ A + +I +LL+ AD
Sbjct: 123 KTALHYAAAQGCLQAVQILC--EHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGAD 180
Query: 102 PNLHSDS-VTPIMAACSNSSADNDTIYSIVCNLIDRNCILNIGDRYGQTPLMRAISSGRV 160
N + S T +M AC S+ + V LI + LN+ D G L + S
Sbjct: 181 VNSRNKSGRTALMLACEIGSS------NAVEALIKKGADLNLVDSLGYNALHYSKLSENA 234
Query: 161 AVAQKLL 167
+ LL
Sbjct: 235 GIQSLLL 241
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.134 0.403
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 52,456,045
Number of Sequences: 224733
Number of extensions: 2143305
Number of successful extensions: 12482
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 697
Number of HSP's successfully gapped in prelim test: 125
Number of HSP's that attempted gapping in prelim test: 8133
Number of HSP's gapped (non-prelim): 2875
length of query: 361
length of database: 73,234,838
effective HSP length: 91
effective length of query: 270
effective length of database: 52,784,135
effective search space: 14251716450
effective search space used: 14251716450
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 66 (30.7 bits)
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