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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001197-TA|BGIBMGA001197-PA|IPR003307|eIF4-
gamma/eIF5/eIF2-epsilon
         (535 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC013590-1|AAH13590.1|  721|Homo sapiens eukaryotic translation ...   187   7e-47
AK091646-1|BAC03712.1|  721|Homo sapiens protein ( Homo sapiens ...   187   7e-47
U23028-1|AAC50646.1|  641|Homo sapiens eIF-2Bepsilon protein.         153   1e-36
AB208821-1|BAD92058.1|  338|Homo sapiens eukaryotic translation ...    62   4e-09
BC009597-1|AAH09597.1|  419|Homo sapiens basic leucine zipper an...    55   5e-07
BC008453-1|AAH08453.1|  419|Homo sapiens basic leucine zipper an...    55   5e-07
BC003056-1|AAH03056.1|  419|Homo sapiens basic leucine zipper an...    55   5e-07
AK001218-1|BAA91562.1|  419|Homo sapiens protein ( Homo sapiens ...    55   5e-07
D13630-1|BAA02795.2|  424|Homo sapiens KIAA0005 protein.               50   2e-05
BC026303-1|AAH26303.1|  419|Homo sapiens BZW1 protein protein.         50   2e-05
AK223245-1|BAD96965.1|  424|Homo sapiens BZW1 protein variant pr...    50   2e-05
AC007163-1|AAX93286.1|  419|Homo sapiens unknown protein.              50   2e-05
BC107757-1|AAI07758.1|  416|Homo sapiens BZW2 protein protein.         50   3e-05
BC017794-1|AAH17794.1|  189|Homo sapiens BZW2 protein protein.         46   3e-04
BT007282-1|AAP35946.1|  645|Homo sapiens eukaryotic translation ...    46   3e-04
BC007788-1|AAH07788.1|  645|Homo sapiens EIF4G1 protein protein.       46   3e-04
AY082886-1|AAL92872.1| 1600|Homo sapiens eukaryotic translation ...    46   3e-04
AK131407-1|BAD18554.1|  451|Homo sapiens protein ( Homo sapiens ...    46   3e-04
AF281070-2|AAM69365.1| 1600|Homo sapiens eukaryotic translation ...    46   3e-04
AF104913-1|AAC82471.1| 1560|Homo sapiens eukaryotic protein synt...    46   3e-04
AB210013-1|BAE06095.1| 1624|Homo sapiens EIF4G1 variant protein ...    46   3e-04
Z34918-1|CAA84397.1|  699|Homo sapiens translation initiationfac...    44   0.002
BC094683-1|AAH94683.1| 1305|Homo sapiens EIF4G3 protein protein.       44   0.002
AL627311-2|CAI14553.1| 1585|Homo sapiens eukaryotic translation ...    44   0.002
AL606477-7|CAI12534.1| 1585|Homo sapiens eukaryotic translation ...    44   0.002
AL358392-2|CAI12155.1| 1585|Homo sapiens eukaryotic translation ...    44   0.002
AF012072-1|AAC02903.2| 1585|Homo sapiens eIF4GII protein.              44   0.002
AB209119-1|BAD92356.1| 1780|Homo sapiens eukaryotic translation ...    44   0.002
BC001804-1|AAH01804.1|  353|Homo sapiens basic leucine zipper an...    42   0.007
BC032866-1|AAH32866.1|  431|Homo sapiens eukaryotic translation ...    39   0.051
CR456712-1|CAG32993.1|  431|Homo sapiens EIF5 protein.                 38   0.067
U49436-1|AAC50572.1|  431|Homo sapiens translation initiation fa...    37   0.16 
BX537367-1|CAD97610.1|  431|Homo sapiens hypothetical protein pr...    37   0.16 
BC007728-1|AAH07728.1|  431|Homo sapiens eukaryotic translation ...    37   0.16 
AK026933-1|BAB15593.1|  431|Homo sapiens protein ( Homo sapiens ...    37   0.16 
BC008033-1|AAH08033.1|  360|Homo sapiens GDP-mannose pyrophospho...    33   3.3  
BC001141-1|AAH01141.1|  360|Homo sapiens GDP-mannose pyrophospho...    33   3.3  
AK024319-1|BAB14882.1|  387|Homo sapiens protein ( Homo sapiens ...    33   3.3  
AF135421-1|AAD38516.1|  360|Homo sapiens GDP-mannose pyrophospho...    33   3.3  
D12686-1|BAA02185.1| 1396|Homo sapiens eIF-4 gamma protein.            32   5.8  
AK222951-1|BAD96671.1|  420|Homo sapiens GDP-mannose pyrophospho...    32   5.8  

>BC013590-1|AAH13590.1|  721|Homo sapiens eukaryotic translation
           initiation factor 2B, subunit 5 epsilon, 82kDa protein.
          Length = 721

 Score =  187 bits (456), Expect = 7e-47
 Identities = 98/274 (35%), Positives = 170/274 (62%), Gaps = 8/274 (2%)

Query: 9   VQAVVIMDTFNSNFSPLTDNKPMGFLEVAGVPLIDYVLESLALGGVGEAILFCCQNGQKI 68
           +QAV++ D+F+  F P++ ++P   L +A V LIDY LE L   GV E  +FCC    +I
Sbjct: 43  LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102

Query: 69  KEHVQKHQDNKSLWSLTMDIQILMSDTCQTMGDVMRELDAAALLKGYFVLAGINSITNMN 128
           KEH+ K +  +   SL + ++I+ S+  +++GDV+R++DA AL++  F+L   + I+N+N
Sbjct: 103 KEHLLKSKWCRPT-SLNV-VRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNIN 160

Query: 129 FASLLEQHKQTCKKDKGTA-MTLVYKKLSWEHPLISSDRSTFLAANENTKKVLVHKRYRP 187
               LE+H+   K +K  + MT+++K+ S  HP    + +  +A +  T +VL    ++ 
Sbjct: 161 ITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVL---HFQK 217

Query: 188 KSKEKIISLPLDLVLNNSE-VKLHHNLVDTNIALCSPTVPPLFSDNFDFQTRDDFIHGIL 246
               +  + PL L   +S+ V++ ++L+D +I++CSP V  LF+DNFD+QTRDDF+ G+L
Sbjct: 218 TQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLL 277

Query: 247 INEEILASSLYYTLLKSNQYAAAITNWKTYQTVC 280
           +NEEIL + ++   + + +Y A ++N   Y  VC
Sbjct: 278 VNEEILGNQIHMH-VTAKEYGARVSNLHMYSAVC 310



 Score =  106 bits (254), Expect = 2e-22
 Identities = 54/171 (31%), Positives = 93/171 (54%), Gaps = 7/171 (4%)

Query: 372 KMFLQEVIDSLARGYDEKLKCDYLILEINSSRYAYNIQLNEVNFFVVRALLSMPVLS--- 428
           K+F  EV+ +L RG +E + CD L+LEINS +YAYN+ L EV   +   +L  P+     
Sbjct: 551 KVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNVSLKEVMQVLSHVVLEFPLQQMDS 610

Query: 429 --EAKNVLTTVKDILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLL 486
             ++      +  +LK + PV  NYIK  +  ++ L A+ED  L  E L     ++L   
Sbjct: 611 PLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAF 670

Query: 487 YEADVVDEDSLVDWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDSE 535
           Y+ +++ E++++ W++  +  +      K   L +F +WL+EA EES + +
Sbjct: 671 YQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD 721


>AK091646-1|BAC03712.1|  721|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34327 fis, clone FEBRA2009022, highly similar to
           TRANSLATION INITIATION FACTOR EIF-2B EPSILON SUBUNIT. ).
          Length = 721

 Score =  187 bits (456), Expect = 7e-47
 Identities = 98/274 (35%), Positives = 170/274 (62%), Gaps = 8/274 (2%)

Query: 9   VQAVVIMDTFNSNFSPLTDNKPMGFLEVAGVPLIDYVLESLALGGVGEAILFCCQNGQKI 68
           +QAV++ D+F+  F P++ ++P   L +A V LIDY LE L   GV E  +FCC    +I
Sbjct: 43  LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102

Query: 69  KEHVQKHQDNKSLWSLTMDIQILMSDTCQTMGDVMRELDAAALLKGYFVLAGINSITNMN 128
           KEH+ K +  +   SL + ++I+ S+  +++GDV+R++DA AL++  F+L   + I+N+N
Sbjct: 103 KEHLLKSKWCRPT-SLNV-VRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNIN 160

Query: 129 FASLLEQHKQTCKKDKGTA-MTLVYKKLSWEHPLISSDRSTFLAANENTKKVLVHKRYRP 187
               LE+H+   K +K  + MT+++K+ S  HP    + +  +A +  T +VL    ++ 
Sbjct: 161 ITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVL---HFQK 217

Query: 188 KSKEKIISLPLDLVLNNSE-VKLHHNLVDTNIALCSPTVPPLFSDNFDFQTRDDFIHGIL 246
               +  + PL L   +S+ V++ ++L+D +I++CSP V  LF+DNFD+QTRDDF+ G+L
Sbjct: 218 TQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLL 277

Query: 247 INEEILASSLYYTLLKSNQYAAAITNWKTYQTVC 280
           +NEEIL + ++   + + +Y A ++N   Y  VC
Sbjct: 278 VNEEILGNQIHMH-VTAKEYGARVSNLHMYSAVC 310



 Score =  106 bits (254), Expect = 2e-22
 Identities = 54/171 (31%), Positives = 93/171 (54%), Gaps = 7/171 (4%)

Query: 372 KMFLQEVIDSLARGYDEKLKCDYLILEINSSRYAYNIQLNEVNFFVVRALLSMPVLS--- 428
           K+F  EV+ +L RG +E + CD L+LEINS +YAYN+ L EV   +   +L  P+     
Sbjct: 551 KVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNVSLKEVMQVLSHVVLEFPLQQMDS 610

Query: 429 --EAKNVLTTVKDILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLL 486
             ++      +  +LK + PV  NYIK  +  ++ L A+ED  L  E L     ++L   
Sbjct: 611 PLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAF 670

Query: 487 YEADVVDEDSLVDWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDSE 535
           Y+ +++ E++++ W++  +  +      K   L +F +WL+EA EES + +
Sbjct: 671 YQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD 721


>U23028-1|AAC50646.1|  641|Homo sapiens eIF-2Bepsilon protein.
          Length = 641

 Score =  153 bits (372), Expect = 1e-36
 Identities = 82/236 (34%), Positives = 144/236 (61%), Gaps = 8/236 (3%)

Query: 47  ESLALGGVGEAILFCCQNGQKIKEHVQKHQDNKSLWSLTMDIQILMSDTCQTMGDVMREL 106
           E L   GV E  +FCC    +IKEH+ K +  +   SL + ++I+ S+  +++GDV+R++
Sbjct: 1   EFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPT-SLNV-VRIITSELYRSLGDVLRDV 58

Query: 107 DAAALLKGYFVLAGINSITNMNFASLLEQHKQTCKKDKGTA-MTLVYKKLSWEHPLISSD 165
           DA AL++  F+L   + I+N+N    LE+H+   K +K  + MT+++K+ S  HP    +
Sbjct: 59  DAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHE 118

Query: 166 RSTFLAANENTKKVLVHKRYRPKSKEKIISLPLDLVLNNSE-VKLHHNLVDTNIALCSPT 224
            +  +A +  T +VL    ++     +  + PL L   +S+ V++ ++L+D +I++CSP 
Sbjct: 119 DNVVVAVDSTTNRVL---HFQKTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQ 175

Query: 225 VPPLFSDNFDFQTRDDFIHGILINEEILASSLYYTLLKSNQYAAAITNWKTYQTVC 280
           V  LF+DNFD+QTRDDF+ G+L+NEEIL + ++   + + +Y A ++N   Y  VC
Sbjct: 176 VAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMH-VTAKEYGARVSNLHMYSAVC 230



 Score =  106 bits (254), Expect = 2e-22
 Identities = 54/171 (31%), Positives = 93/171 (54%), Gaps = 7/171 (4%)

Query: 372 KMFLQEVIDSLARGYDEKLKCDYLILEINSSRYAYNIQLNEVNFFVVRALLSMPVLS--- 428
           K+F  EV+ +L RG +E + CD L+LEINS +YAYN+ L EV   +   +L  P+     
Sbjct: 471 KVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNVSLKEVMQVLSHVVLEFPLQQMDS 530

Query: 429 --EAKNVLTTVKDILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLL 486
             ++      +  +LK + PV  NYIK  +  ++ L A+ED  L  E L     ++L   
Sbjct: 531 PLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAF 590

Query: 487 YEADVVDEDSLVDWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDSE 535
           Y+ +++ E++++ W++  +  +      K   L +F +WL+EA EES + +
Sbjct: 591 YQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD 641


>AB208821-1|BAD92058.1|  338|Homo sapiens eukaryotic translation
           initiation factor 2B, subunit 5 epsilon, 82kDa variant
           protein.
          Length = 338

 Score = 62.5 bits (145), Expect = 4e-09
 Identities = 26/56 (46%), Positives = 39/56 (69%), Gaps = 1/56 (1%)

Query: 225 VPPLFSDNFDFQTRDDFIHGILINEEILASSLYYTLLKSNQYAAAITNWKTYQTVC 280
           V  LF+DNFD+QTRDDF+ G+L+NEEIL + ++   + + +Y A ++N   Y  VC
Sbjct: 12  VAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMH-VTAKEYGARVSNLHMYSAVC 66



 Score = 38.3 bits (85), Expect = 0.067
 Identities = 16/30 (53%), Positives = 22/30 (73%)

Query: 372 KMFLQEVIDSLARGYDEKLKCDYLILEINS 401
           K+F  EV+ +L RG +E + CD L+LEINS
Sbjct: 307 KVFQNEVLGTLQRGKEENISCDNLVLEINS 336


>BC009597-1|AAH09597.1|  419|Homo sapiens basic leucine zipper and
           W2 domains 2 protein.
          Length = 419

 Score = 55.2 bits (127), Expect = 5e-07
 Identities = 30/92 (32%), Positives = 48/92 (52%)

Query: 441 LKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVDW 500
           LK + P+LA +     S +  L+ V++ C +         +I+ L Y+ADV+ E++++ W
Sbjct: 322 LKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKW 381

Query: 501 YAELKENANPFVKQPSLVKFFEWLQEASEESD 532
           Y E        V    + KF EWLQ A EES+
Sbjct: 382 YKEAHVAKGKSVFLDQMKKFVEWLQNAEEESE 413


>BC008453-1|AAH08453.1|  419|Homo sapiens basic leucine zipper and
           W2 domains 2 protein.
          Length = 419

 Score = 55.2 bits (127), Expect = 5e-07
 Identities = 30/92 (32%), Positives = 48/92 (52%)

Query: 441 LKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVDW 500
           LK + P+LA +     S +  L+ V++ C +         +I+ L Y+ADV+ E++++ W
Sbjct: 322 LKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKW 381

Query: 501 YAELKENANPFVKQPSLVKFFEWLQEASEESD 532
           Y E        V    + KF EWLQ A EES+
Sbjct: 382 YKEAHVAKGKSVFLDQMKKFVEWLQNAEEESE 413


>BC003056-1|AAH03056.1|  419|Homo sapiens basic leucine zipper and
           W2 domains 2 protein.
          Length = 419

 Score = 55.2 bits (127), Expect = 5e-07
 Identities = 30/92 (32%), Positives = 48/92 (52%)

Query: 441 LKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVDW 500
           LK + P+LA +     S +  L+ V++ C +         +I+ L Y+ADV+ E++++ W
Sbjct: 322 LKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKW 381

Query: 501 YAELKENANPFVKQPSLVKFFEWLQEASEESD 532
           Y E        V    + KF EWLQ A EES+
Sbjct: 382 YKEAHVAKGKSVFLDQMKKFVEWLQNAEEESE 413


>AK001218-1|BAA91562.1|  419|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10356 fis, clone NT2RM2001201, weakly similar to
           EUKARYOTIC TRANSLATION INITIATION FACTOR 5. ).
          Length = 419

 Score = 55.2 bits (127), Expect = 5e-07
 Identities = 30/92 (32%), Positives = 48/92 (52%)

Query: 441 LKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVDW 500
           LK + P+LA +     S +  L+ V++ C +         +I+ L Y+ADV+ E++++ W
Sbjct: 322 LKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKW 381

Query: 501 YAELKENANPFVKQPSLVKFFEWLQEASEESD 532
           Y E        V    + KF EWLQ A EES+
Sbjct: 382 YKEAHVAKGKSVFLDQMKKFVEWLQNAEEESE 413


>D13630-1|BAA02795.2|  424|Homo sapiens KIAA0005 protein.
          Length = 424

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 28/94 (29%), Positives = 52/94 (55%), Gaps = 4/94 (4%)

Query: 441 LKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVDW 500
           LK + P+LA +     S +  L  +++ C +         +I+ L Y+A+V+ E+ ++ W
Sbjct: 326 LKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKW 385

Query: 501 Y--AELKENANPFVKQPSLVKFFEWLQEASEESD 532
           Y  A + +  + F++Q  + KF EWL+ A EES+
Sbjct: 386 YKDAHVAKGKSVFLEQ--MKKFVEWLKNAEEESE 417


>BC026303-1|AAH26303.1|  419|Homo sapiens BZW1 protein protein.
          Length = 419

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 28/94 (29%), Positives = 52/94 (55%), Gaps = 4/94 (4%)

Query: 441 LKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVDW 500
           LK + P+LA +     S +  L  +++ C +         +I+ L Y+A+V+ E+ ++ W
Sbjct: 321 LKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKW 380

Query: 501 Y--AELKENANPFVKQPSLVKFFEWLQEASEESD 532
           Y  A + +  + F++Q  + KF EWL+ A EES+
Sbjct: 381 YKDAHVAKGKSVFLEQ--MKKFVEWLKNAEEESE 412


>AK223245-1|BAD96965.1|  424|Homo sapiens BZW1 protein variant
           protein.
          Length = 424

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 28/94 (29%), Positives = 52/94 (55%), Gaps = 4/94 (4%)

Query: 441 LKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVDW 500
           LK + P+LA +     S +  L  +++ C +         +I+ L Y+A+V+ E+ ++ W
Sbjct: 326 LKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKW 385

Query: 501 Y--AELKENANPFVKQPSLVKFFEWLQEASEESD 532
           Y  A + +  + F++Q  + KF EWL+ A EES+
Sbjct: 386 YKDAHVAKGKSVFLEQ--MKKFVEWLKNAEEESE 417


>AC007163-1|AAX93286.1|  419|Homo sapiens unknown protein.
          Length = 419

 Score = 50.0 bits (114), Expect = 2e-05
 Identities = 28/94 (29%), Positives = 52/94 (55%), Gaps = 4/94 (4%)

Query: 441 LKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVDW 500
           LK + P+LA +     S +  L  +++ C +         +I+ L Y+A+V+ E+ ++ W
Sbjct: 321 LKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKW 380

Query: 501 Y--AELKENANPFVKQPSLVKFFEWLQEASEESD 532
           Y  A + +  + F++Q  + KF EWL+ A EES+
Sbjct: 381 YKDAHVAKGKSVFLEQ--MKKFVEWLKNAEEESE 412


>BC107757-1|AAI07758.1|  416|Homo sapiens BZW2 protein protein.
          Length = 416

 Score = 49.6 bits (113), Expect = 3e-05
 Identities = 27/90 (30%), Positives = 46/90 (51%)

Query: 441 LKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVDW 500
           LK + P+LA +     S +  L+ V++ C +         +I+ L Y+ADV+ E++++ W
Sbjct: 322 LKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKW 381

Query: 501 YAELKENANPFVKQPSLVKFFEWLQEASEE 530
           Y E        V    + KF EWLQ A ++
Sbjct: 382 YKEAHVAKGKSVFLDQMKKFVEWLQNAKKK 411


>BC017794-1|AAH17794.1|  189|Homo sapiens BZW2 protein protein.
          Length = 189

 Score = 46.4 bits (105), Expect = 3e-04
 Identities = 21/52 (40%), Positives = 31/52 (59%)

Query: 481 QILHLLYEADVVDEDSLVDWYAELKENANPFVKQPSLVKFFEWLQEASEESD 532
           +I+ L Y+ADV+ E++++ WY E        V    + KF EWLQ A EES+
Sbjct: 132 KIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESE 183


>BT007282-1|AAP35946.1|  645|Homo sapiens eukaryotic translation
           initiation factor 4 gamma, 1 protein.
          Length = 645

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 440 ILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVD 499
           +LK    +L  Y+  +   +  L A++   +  E            LY+ DVV ED+   
Sbjct: 549 VLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYS 608

Query: 500 WYA--ELKENANPFVKQPSLVKFFEWLQEASEESD 532
           W +  +  E     V   S+  FF+WL+EA EESD
Sbjct: 609 WESSKDPAEQQGKGVALKSVTAFFKWLREAEEESD 643


>BC007788-1|AAH07788.1|  645|Homo sapiens EIF4G1 protein protein.
          Length = 645

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 440 ILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVD 499
           +LK    +L  Y+  +   +  L A++   +  E            LY+ DVV ED+   
Sbjct: 549 VLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYS 608

Query: 500 WYA--ELKENANPFVKQPSLVKFFEWLQEASEESD 532
           W +  +  E     V   S+  FF+WL+EA EESD
Sbjct: 609 WESSKDPAEQQGKGVALKSVTAFFKWLREAEEESD 643


>AY082886-1|AAL92872.1| 1600|Homo sapiens eukaryotic translation
            initiation factor 4GI protein.
          Length = 1600

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 440  ILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVD 499
            +LK    +L  Y+  +   +  L A++   +  E            LY+ DVV ED+   
Sbjct: 1504 VLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYS 1563

Query: 500  WYA--ELKENANPFVKQPSLVKFFEWLQEASEESD 532
            W +  +  E     V   S+  FF+WL+EA EESD
Sbjct: 1564 WESSKDPAEQQGKGVALKSVTAFFKWLREAEEESD 1598


>AK131407-1|BAD18554.1|  451|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16513 fis, clone MESAN2001770, highly  similar
           to EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA. ).
          Length = 451

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 440 ILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVD 499
           +LK    +L  Y+  +   +  L A++   +  E            LY+ DVV ED+   
Sbjct: 355 VLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYS 414

Query: 500 WYA--ELKENANPFVKQPSLVKFFEWLQEASEESD 532
           W +  +  E     V   S+  FF+WL+EA EESD
Sbjct: 415 WESSKDPAEQQGKGVALKSVTAFFKWLREAEEESD 449


>AF281070-2|AAM69365.1| 1600|Homo sapiens eukaryotic translation
            initiation factor 4G I protein.
          Length = 1600

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 440  ILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVD 499
            +LK    +L  Y+  +   +  L A++   +  E            LY+ DVV ED+   
Sbjct: 1504 VLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYS 1563

Query: 500  WYA--ELKENANPFVKQPSLVKFFEWLQEASEESD 532
            W +  +  E     V   S+  FF+WL+EA EESD
Sbjct: 1564 WESSKDPAEQQGKGVALKSVTAFFKWLREAEEESD 1598


>AF104913-1|AAC82471.1| 1560|Homo sapiens eukaryotic protein synthesis
            initiation factor protein.
          Length = 1560

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 440  ILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVD 499
            +LK    +L  Y+  +   +  L A++   +  E            LY+ DVV ED+   
Sbjct: 1464 VLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYS 1523

Query: 500  WYA--ELKENANPFVKQPSLVKFFEWLQEASEESD 532
            W +  +  E     V   S+  FF+WL+EA EESD
Sbjct: 1524 WESSKDPAEQQGKGVALKSVTAFFKWLREAEEESD 1558


>AB210013-1|BAE06095.1| 1624|Homo sapiens EIF4G1 variant protein
            protein.
          Length = 1624

 Score = 46.0 bits (104), Expect = 3e-04
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 2/95 (2%)

Query: 440  ILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLVD 499
            +LK    +L  Y+  +   +  L A++   +  E            LY+ DVV ED+   
Sbjct: 1528 VLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYS 1587

Query: 500  WYA--ELKENANPFVKQPSLVKFFEWLQEASEESD 532
            W +  +  E     V   S+  FF+WL+EA EESD
Sbjct: 1588 WESSKDPAEQQGKGVALKSVTAFFKWLREAEEESD 1622


>Z34918-1|CAA84397.1|  699|Homo sapiens translation initiationfactor
           eIF-4gamma protein.
          Length = 699

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 440 ILKYFRPVLANYIKSKSSI-MDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLV 498
           ++K   P+L  Y+ S +   +  L A++ + +  +            LY+ +V+ ED+  
Sbjct: 602 VIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFY 661

Query: 499 DWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDS 534
            W +  +  E     V   S+  FF WL+EA EES+D+
Sbjct: 662 KWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 699


>BC094683-1|AAH94683.1| 1305|Homo sapiens EIF4G3 protein protein.
          Length = 1305

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 440  ILKYFRPVLANYIKSKSSI-MDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLV 498
            ++K   P+L  Y+ S +   +  L A++ + +  +            LY+ +V+ ED+  
Sbjct: 1208 VIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFY 1267

Query: 499  DWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDS 534
             W +  +  E     V   S+  FF WL+EA EES+D+
Sbjct: 1268 KWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1305


>AL627311-2|CAI14553.1| 1585|Homo sapiens eukaryotic translation
            initiation factor 4 gamma,actor receptor 3 (achondroplas
            protein.
          Length = 1585

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 440  ILKYFRPVLANYIKSKSSI-MDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLV 498
            ++K   P+L  Y+ S +   +  L A++ + +  +            LY+ +V+ ED+  
Sbjct: 1488 VIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFY 1547

Query: 499  DWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDS 534
             W +  +  E     V   S+  FF WL+EA EES+D+
Sbjct: 1548 KWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585


>AL606477-7|CAI12534.1| 1585|Homo sapiens eukaryotic translation
            initiation factor 4 gamma,1 protein.
          Length = 1585

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 440  ILKYFRPVLANYIKSKSSI-MDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLV 498
            ++K   P+L  Y+ S +   +  L A++ + +  +            LY+ +V+ ED+  
Sbjct: 1488 VIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFY 1547

Query: 499  DWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDS 534
             W +  +  E     V   S+  FF WL+EA EES+D+
Sbjct: 1548 KWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585


>AL358392-2|CAI12155.1| 1585|Homo sapiens eukaryotic translation
            initiation factor 4 gamma,fluid) protein.
          Length = 1585

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 440  ILKYFRPVLANYIKSKSSI-MDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLV 498
            ++K   P+L  Y+ S +   +  L A++ + +  +            LY+ +V+ ED+  
Sbjct: 1488 VIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFY 1547

Query: 499  DWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDS 534
             W +  +  E     V   S+  FF WL+EA EES+D+
Sbjct: 1548 KWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585


>AF012072-1|AAC02903.2| 1585|Homo sapiens eIF4GII protein.
          Length = 1585

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 440  ILKYFRPVLANYIKSKSSI-MDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLV 498
            ++K   P+L  Y+ S +   +  L A++ + +  +            LY+ +V+ ED+  
Sbjct: 1488 VIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFY 1547

Query: 499  DWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDS 534
             W +  +  E     V   S+  FF WL+EA EES+D+
Sbjct: 1548 KWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585


>AB209119-1|BAD92356.1| 1780|Homo sapiens eukaryotic translation
            initiation factor 4 gamma, 3 variant protein.
          Length = 1780

 Score = 43.6 bits (98), Expect = 0.002
 Identities = 26/98 (26%), Positives = 47/98 (47%), Gaps = 3/98 (3%)

Query: 440  ILKYFRPVLANYIKSKSSI-MDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDSLV 498
            ++K   P+L  Y+ S +   +  L A++ + +  +            LY+ +V+ ED+  
Sbjct: 1683 VIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFY 1742

Query: 499  DWYA--ELKENANPFVKQPSLVKFFEWLQEASEESDDS 534
             W +  +  E     V   S+  FF WL+EA EES+D+
Sbjct: 1743 KWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1780


>BC001804-1|AAH01804.1|  353|Homo sapiens basic leucine zipper and
           W2 domains 1 protein.
          Length = 353

 Score = 41.5 bits (93), Expect = 0.007
 Identities = 20/54 (37%), Positives = 36/54 (66%), Gaps = 4/54 (7%)

Query: 481 QILHLLYEADVVDEDSLVDWY--AELKENANPFVKQPSLVKFFEWLQEASEESD 532
           +I+ L Y+A+V+ E+ ++ WY  A + +  + F++Q  + KF EWL+ A EES+
Sbjct: 295 KIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQ--MKKFVEWLKNAEEESE 346


>BC032866-1|AAH32866.1|  431|Homo sapiens eukaryotic translation
           initiation factor 5 protein.
          Length = 431

 Score = 38.7 bits (86), Expect = 0.051
 Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 6/103 (5%)

Query: 437 VKDILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDS 496
           +K   ++F     N  K+K  ++  L  V    ++   L  K   IL  +Y+AD+++E+ 
Sbjct: 293 IKKYRRHFLRFCHNNKKAKRYLLHGLECV--VAMHQAQLISKIPHILKEMYDADLLEEEV 350

Query: 497 LVDWYAEL-KENANPFVKQPSLVK---FFEWLQEASEESDDSE 535
           ++ W  +  K+  +  + +   VK   F +WL+EA EES   E
Sbjct: 351 IISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGE 393


>CR456712-1|CAG32993.1|  431|Homo sapiens EIF5 protein.
          Length = 431

 Score = 38.3 bits (85), Expect = 0.067
 Identities = 27/103 (26%), Positives = 52/103 (50%), Gaps = 6/103 (5%)

Query: 437 VKDILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDS 496
           +K+  ++F     N  K++  ++  L  V    ++   L  K   IL  +Y+AD+++E+ 
Sbjct: 293 IKEYRRHFLRFCHNNKKAQRYLLHGLECV--VAMHQAQLISKIPHILKEMYDADLLEEEV 350

Query: 497 LVDWYAEL-KENANPFVKQPSLVK---FFEWLQEASEESDDSE 535
           ++ W  +  K+  +  + +   VK   F +WL+EA EES   E
Sbjct: 351 IISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGE 393


>U49436-1|AAC50572.1|  431|Homo sapiens translation initiation
           factor 5 protein.
          Length = 431

 Score = 37.1 bits (82), Expect = 0.16
 Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 6/103 (5%)

Query: 437 VKDILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDS 496
           +K   ++F     N  K++  ++  L  V    ++   L  K   IL  +Y+AD+++E+ 
Sbjct: 293 IKKYRRHFLRFCHNNKKAQRYLLHGLECV--VAMHQAQLISKIPHILKEMYDADLLEEEV 350

Query: 497 LVDWYAEL-KENANPFVKQPSLVK---FFEWLQEASEESDDSE 535
           ++ W  +  K+  +  + +   VK   F +WL+EA EES   E
Sbjct: 351 IISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGE 393


>BX537367-1|CAD97610.1|  431|Homo sapiens hypothetical protein
           protein.
          Length = 431

 Score = 37.1 bits (82), Expect = 0.16
 Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 6/103 (5%)

Query: 437 VKDILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDS 496
           +K   ++F     N  K++  ++  L  V    ++   L  K   IL  +Y+AD+++E+ 
Sbjct: 293 IKKYRRHFLRFCHNNKKAQRYLLHGLECV--VAMHQAQLISKIPHILKEMYDADLLEEEV 350

Query: 497 LVDWYAEL-KENANPFVKQPSLVK---FFEWLQEASEESDDSE 535
           ++ W  +  K+  +  + +   VK   F +WL+EA EES   E
Sbjct: 351 IISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGE 393


>BC007728-1|AAH07728.1|  431|Homo sapiens eukaryotic translation
           initiation factor 5 protein.
          Length = 431

 Score = 37.1 bits (82), Expect = 0.16
 Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 6/103 (5%)

Query: 437 VKDILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDS 496
           +K   ++F     N  K++  ++  L  V    ++   L  K   IL  +Y+AD+++E+ 
Sbjct: 293 IKKYRRHFLRFCHNNKKAQRYLLHGLECV--VAMHQAQLISKIPHILKEMYDADLLEEEV 350

Query: 497 LVDWYAEL-KENANPFVKQPSLVK---FFEWLQEASEESDDSE 535
           ++ W  +  K+  +  + +   VK   F +WL+EA EES   E
Sbjct: 351 IISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGE 393


>AK026933-1|BAB15593.1|  431|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ23280 fis, clone HEP07194. ).
          Length = 431

 Score = 37.1 bits (82), Expect = 0.16
 Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 6/103 (5%)

Query: 437 VKDILKYFRPVLANYIKSKSSIMDCLRAVEDTCLNCEWLDGKSGQILHLLYEADVVDEDS 496
           +K   ++F     N  K++  ++  L  V    ++   L  K   IL  +Y+AD+++E+ 
Sbjct: 293 IKKYRRHFLRFCHNNKKAQRYLLHGLECV--VAMHQAQLISKIPHILKEMYDADLLEEEV 350

Query: 497 LVDWYAEL-KENANPFVKQPSLVK---FFEWLQEASEESDDSE 535
           ++ W  +  K+  +  + +   VK   F +WL+EA EES   E
Sbjct: 351 IISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGE 393


>BC008033-1|AAH08033.1|  360|Homo sapiens GDP-mannose
           pyrophosphorylase B protein.
          Length = 360

 Score = 32.7 bits (71), Expect = 3.3
 Identities = 25/129 (19%), Positives = 58/129 (44%), Gaps = 4/129 (3%)

Query: 9   VQAVVIMDTFNSNFSPLTDNKPMGFLEVAGVPLIDYVLESLALGGVGEAILFCCQNGQKI 68
           ++A++++  + +   PLT + P   ++    P++ + +E+LA  GV   IL      Q +
Sbjct: 1   MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQ-V 59

Query: 69  KEHVQKHQDNKSLWSLTMDIQILMSDTCQTMGDVMRELDAAALLKGYFVLAGINSITNMN 128
            E   K Q+ +    ++M  +    +   T G +    D  +     F +   + I +  
Sbjct: 60  LEKEMKAQEQRLGIRISMSHE---EEPLGTAGPLALARDLLSETADPFFVLNSDVICDFP 116

Query: 129 FASLLEQHK 137
           F ++++ H+
Sbjct: 117 FQAMVQFHR 125


>BC001141-1|AAH01141.1|  360|Homo sapiens GDP-mannose
           pyrophosphorylase B protein.
          Length = 360

 Score = 32.7 bits (71), Expect = 3.3
 Identities = 25/129 (19%), Positives = 58/129 (44%), Gaps = 4/129 (3%)

Query: 9   VQAVVIMDTFNSNFSPLTDNKPMGFLEVAGVPLIDYVLESLALGGVGEAILFCCQNGQKI 68
           ++A++++  + +   PLT + P   ++    P++ + +E+LA  GV   IL      Q +
Sbjct: 1   MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQ-V 59

Query: 69  KEHVQKHQDNKSLWSLTMDIQILMSDTCQTMGDVMRELDAAALLKGYFVLAGINSITNMN 128
            E   K Q+ +    ++M  +    +   T G +    D  +     F +   + I +  
Sbjct: 60  LEKEMKAQEQRLGIRISMSHE---EEPLGTAGPLALARDLLSETADPFFVLNSDVICDFP 116

Query: 129 FASLLEQHK 137
           F ++++ H+
Sbjct: 117 FQAMVQFHR 125


>AK024319-1|BAB14882.1|  387|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14257 fis, clone PLACE1000547, highly similar to
           Homo sapiens GDP-mannose pyrophosphorylase B (GMPPB)
           mRNA. ).
          Length = 387

 Score = 32.7 bits (71), Expect = 3.3
 Identities = 25/129 (19%), Positives = 58/129 (44%), Gaps = 4/129 (3%)

Query: 9   VQAVVIMDTFNSNFSPLTDNKPMGFLEVAGVPLIDYVLESLALGGVGEAILFCCQNGQKI 68
           ++A++++  + +   PLT + P   ++    P++ + +E+LA  GV   IL      Q +
Sbjct: 1   MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQ-V 59

Query: 69  KEHVQKHQDNKSLWSLTMDIQILMSDTCQTMGDVMRELDAAALLKGYFVLAGINSITNMN 128
            E   K Q+ +    ++M  +    +   T G +    D  +     F +   + I +  
Sbjct: 60  LEKEMKAQEQRLGIRISMSHE---EEPLGTAGPLALARDLLSETADPFFVLNSDVICDFP 116

Query: 129 FASLLEQHK 137
           F ++++ H+
Sbjct: 117 FQAMVQFHR 125


>AF135421-1|AAD38516.1|  360|Homo sapiens GDP-mannose
           pyrophosphorylase B protein.
          Length = 360

 Score = 32.7 bits (71), Expect = 3.3
 Identities = 25/129 (19%), Positives = 58/129 (44%), Gaps = 4/129 (3%)

Query: 9   VQAVVIMDTFNSNFSPLTDNKPMGFLEVAGVPLIDYVLESLALGGVGEAILFCCQNGQKI 68
           ++A++++  + +   PLT + P   ++    P++ + +E+LA  GV   IL      Q +
Sbjct: 1   MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQ-V 59

Query: 69  KEHVQKHQDNKSLWSLTMDIQILMSDTCQTMGDVMRELDAAALLKGYFVLAGINSITNMN 128
            E   K Q+ +    ++M  +    +   T G +    D  +     F +   + I +  
Sbjct: 60  LEKEMKAQEQRLGIRISMSHE---EEPLGTAGPLALARDLLSETADPFFVLNSDVICDFP 116

Query: 129 FASLLEQHK 137
           F ++++ H+
Sbjct: 117 FQAMVQFHR 125


>D12686-1|BAA02185.1| 1396|Homo sapiens eIF-4 gamma protein.
          Length = 1396

 Score = 31.9 bits (69), Expect = 5.8
 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 2/43 (4%)

Query: 486  LYEADVVDEDSLVDWYA--ELKENANPFVKQPSLVKFFEWLQE 526
            LY+ DVV ED+   W +  +  E     V   S+  FF+WL+E
Sbjct: 1349 LYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLRE 1391


>AK222951-1|BAD96671.1|  420|Homo sapiens GDP-mannose
          pyrophosphorylase A variant protein.
          Length = 420

 Score = 31.9 bits (69), Expect = 5.8
 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 1/43 (2%)

Query: 20 SNFSPLTDNKPMGFLEVAGVPLIDYVLESLA-LGGVGEAILFC 61
          + F PL+   P     VAGVP+I + +E+ A + G+ E +L C
Sbjct: 15 TRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIC 57


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.318    0.134    0.390 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 68,419,010
Number of Sequences: 224733
Number of extensions: 2643556
Number of successful extensions: 5560
Number of sequences better than 10.0: 41
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 5494
Number of HSP's gapped (non-prelim): 49
length of query: 535
length of database: 73,234,838
effective HSP length: 93
effective length of query: 442
effective length of database: 52,334,669
effective search space: 23131923698
effective search space used: 23131923698
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)

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