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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001188-TA|BGIBMGA001188-PA|IPR001247|Exoribonuclease,
IPR012462|Protein of unknown function DUF1671
         (805 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CR457278-1|CAG33559.1|  469|Homo sapiens FLJ11200 protein.            314   8e-85
BC010493-1|AAH10493.1|  469|Homo sapiens chromosome 4 open readi...   314   8e-85
AK002062-1|BAA92064.1|  469|Homo sapiens protein ( Homo sapiens ...   312   2e-84
BC020773-1|AAH20773.1|  276|Homo sapiens exosome component 8 pro...   235   6e-61
AF025438-1|AAC39558.1|  265|Homo sapiens Opa-interacting protein...   232   3e-60
AL138706-8|CAI14013.1|  275|Homo sapiens RP11-421P11.3 protein.       230   1e-59
AJ517294-1|CAD56889.1|  456|Homo sapiens polymyositis/scleroderm...   128   1e-28
AJ505989-1|CAD44530.1|  439|Homo sapiens polymyositis/scleroderm...   128   1e-28
D29958-1|BAA06226.1|  290|Homo sapiens KIAA0116 protein.              105   5e-22
BC012831-1|AAH12831.1|  291|Homo sapiens exosome component 7 pro...   105   5e-22
U09215-1|AAA18832.1|  372|Homo sapiens PM-Scl-75 autoantigen pro...    92   6e-18
M58460-1|AAA58384.1|  355|Homo sapiens autoantigen protein.            92   6e-18
AC079341-2|AAY40968.1|  355|Homo sapiens unknown protein.              92   6e-18
BC067904-1|AAH67904.1|  142|Homo sapiens similar to RIKEN cDNA 2...    83   4e-15
AF312032-2|AAK21004.1|  142|Homo sapiens unknown protein.              83   5e-15
BC053660-1|AAH53660.1|  783|Homo sapiens polyribonucleotide nucl...    34   1.7  
AY027528-1|AAK13047.1|  783|Homo sapiens 3'-5' RNA exonuclease p...    34   1.7  
AK027437-1|BAB55109.1|  504|Homo sapiens protein ( Homo sapiens ...    34   1.7  
AJ458465-1|CAD30289.1|  783|Homo sapiens polynucleotide phosphor...    34   1.7  
AC015982-3|AAY24271.1|  783|Homo sapiens unknown protein.              34   1.7  
BX537872-1|CAD97873.1|  578|Homo sapiens hypothetical protein pr...    34   2.3  
BC016879-1|AAH16879.1|  578|Homo sapiens chromosome 6 open readi...    34   2.3  
AL132795-3|CAI20498.1|  578|Homo sapiens RP3-412I7.3 protein.          34   2.3  
AK054582-1|BAB70765.1|  578|Homo sapiens protein ( Homo sapiens ...    33   3.0  
X52022-1|CAA36267.1| 3176|Homo sapiens collagen type VI, alpha 3...    32   9.3  
BX641155-1|CAE46068.1|  558|Homo sapiens hypothetical protein pr...    32   9.3  
BC071564-1|AAH71564.1| 1224|Homo sapiens bromodomain and WD repe...    32   9.3  
BC040469-1|AAH40469.1| 1224|Homo sapiens bromodomain and WD repe...    32   9.3  
BC033174-1|AAH33174.1|  979|Homo sapiens Similar to collagen, ty...    32   9.3  
AL391425-1|CAH72488.1| 1224|Homo sapiens WD repeat domain 11 pro...    32   9.3  
AK001368-1|BAA91652.1|  864|Homo sapiens protein ( Homo sapiens ...    32   9.3  
AK000579-1|BAA91269.1|  515|Homo sapiens protein ( Homo sapiens ...    32   9.3  
AF320223-1|AAK08064.1| 1224|Homo sapiens WD40 repeat domain 11 p...    32   9.3  
AC112715-1|AAY14906.1|  588|Homo sapiens unknown protein.              32   9.3  
AB209636-1|BAD92873.1| 1702|Homo sapiens alpha 3 type VI collage...    32   9.3  
AB037772-1|BAA92589.2| 1243|Homo sapiens KIAA1351 protein protein.     32   9.3  

>CR457278-1|CAG33559.1|  469|Homo sapiens FLJ11200 protein.
          Length = 469

 Score =  314 bits (771), Expect = 8e-85
 Identities = 138/247 (55%), Positives = 182/247 (73%), Gaps = 6/247 (2%)

Query: 561 QLEKERRTLHEQLGLPLHRPVFRRGNA--FIDK--SGGYLVNPHEAMPIQASKSDVTVAL 616
           QL+  R+ LH+   LP  RP F+R NA  F D+    GY+ NPH  +     ++ + + +
Sbjct: 222 QLQAYRKELHDLFNLPHDRPYFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNMETGM-IYV 280

Query: 617 VRGRYAYHHYMQDNFNDDGWGCAYRSMQTIFSWFRYQGYTDVEVPTHKEIQQCLVKIGDK 676
           V+G Y YHHYMQD  +D+GWGCAYRS+QTI SWF++QGYT+  +PTH+EIQQ LV  GDK
Sbjct: 281 VQGIYGYHHYMQDRIDDNGWGCAYRSLQTICSWFKHQGYTERSIPTHREIQQALVDAGDK 340

Query: 677 QSTFIGSKQWIGSTEVMFCLETLLGVQSRIIFANTGTELQSYAPELVHHFQTHGSPIMIG 736
            +TF+GS+QWIGS EV   L  L+G+ S+I+F + G+E+ S   EL +HFQ+ G+P+MIG
Sbjct: 341 PATFVGSRQWIGSIEVQLVLNQLIGITSKILFVSQGSEIASQGRELANHFQSEGTPVMIG 400

Query: 737 GGVLAHTILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNL 796
           GGVLAHTILG+ +N IT + ++LILDPHYTGAED+  ++ KGWCGWK  DFWNK A+YNL
Sbjct: 401 GGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNL 460

Query: 797 CLPQTRP 803
           CLPQ RP
Sbjct: 461 CLPQ-RP 466


>BC010493-1|AAH10493.1|  469|Homo sapiens chromosome 4 open reading
           frame 20 protein.
          Length = 469

 Score =  314 bits (771), Expect = 8e-85
 Identities = 138/247 (55%), Positives = 182/247 (73%), Gaps = 6/247 (2%)

Query: 561 QLEKERRTLHEQLGLPLHRPVFRRGNA--FIDK--SGGYLVNPHEAMPIQASKSDVTVAL 616
           QL+  R+ LH+   LP  RP F+R NA  F D+    GY+ NPH  +     ++ + + +
Sbjct: 222 QLQAYRKELHDLFNLPHDRPYFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNMETGM-IYV 280

Query: 617 VRGRYAYHHYMQDNFNDDGWGCAYRSMQTIFSWFRYQGYTDVEVPTHKEIQQCLVKIGDK 676
           V+G Y YHHYMQD  +D+GWGCAYRS+QTI SWF++QGYT+  +PTH+EIQQ LV  GDK
Sbjct: 281 VQGIYGYHHYMQDRIDDNGWGCAYRSLQTICSWFKHQGYTERSIPTHREIQQALVDAGDK 340

Query: 677 QSTFIGSKQWIGSTEVMFCLETLLGVQSRIIFANTGTELQSYAPELVHHFQTHGSPIMIG 736
            +TF+GS+QWIGS EV   L  L+G+ S+I+F + G+E+ S   EL +HFQ+ G+P+MIG
Sbjct: 341 PATFVGSRQWIGSIEVQLVLNQLIGITSKILFVSQGSEIASQGRELANHFQSEGTPVMIG 400

Query: 737 GGVLAHTILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNL 796
           GGVLAHTILG+ +N IT + ++LILDPHYTGAED+  ++ KGWCGWK  DFWNK A+YNL
Sbjct: 401 GGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNL 460

Query: 797 CLPQTRP 803
           CLPQ RP
Sbjct: 461 CLPQ-RP 466


>AK002062-1|BAA92064.1|  469|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11200 fis, clone PLACE1007725. ).
          Length = 469

 Score =  312 bits (767), Expect = 2e-84
 Identities = 138/247 (55%), Positives = 181/247 (73%), Gaps = 6/247 (2%)

Query: 561 QLEKERRTLHEQLGLPLHRPVFRRGNA--FIDK--SGGYLVNPHEAMPIQASKSDVTVAL 616
           QL+  R+ LH    LP  RP F+R NA  F D+    GY+ NPH  +     ++ + + +
Sbjct: 222 QLQAYRKELHGLFNLPHDRPYFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNMETGM-IYV 280

Query: 617 VRGRYAYHHYMQDNFNDDGWGCAYRSMQTIFSWFRYQGYTDVEVPTHKEIQQCLVKIGDK 676
           V+G Y YHHYMQD  +D+GWGCAYRS+QTI SWF++QGYT+  +PTH+EIQQ LV  GDK
Sbjct: 281 VQGIYGYHHYMQDRIDDNGWGCAYRSLQTICSWFKHQGYTERSIPTHREIQQALVDAGDK 340

Query: 677 QSTFIGSKQWIGSTEVMFCLETLLGVQSRIIFANTGTELQSYAPELVHHFQTHGSPIMIG 736
            +TF+GS+QWIGS EV   L  L+G+ S+I+F + G+E+ S   EL +HFQ+ G+P+MIG
Sbjct: 341 PATFVGSRQWIGSIEVQLVLNQLIGITSKILFVSQGSEIASQGRELANHFQSEGTPVMIG 400

Query: 737 GGVLAHTILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNL 796
           GGVLAHTILG+ +N IT + ++LILDPHYTGAED+  ++ KGWCGWK  DFWNK A+YNL
Sbjct: 401 GGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNL 460

Query: 797 CLPQTRP 803
           CLPQ RP
Sbjct: 461 CLPQ-RP 466


>BC020773-1|AAH20773.1|  276|Homo sapiens exosome component 8
           protein.
          Length = 276

 Score =  235 bits (574), Expect = 6e-61
 Identities = 109/275 (39%), Positives = 171/275 (62%), Gaps = 6/275 (2%)

Query: 1   MSEVYKLIHPVKHFNDYISIKTRLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVC 60
           M+  +K + P++++  ++    R DGR   E R   +N+ SI TAD SA+VK GNTTV+C
Sbjct: 1   MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVIC 60

Query: 61  GIKLELAVPKAEEPDLGFLITNVELPALCSSKYRPGPPSDYAQVINNIVSEIIKNSKCID 120
           G+K E A P  + PD G+++ NV+LP LCSS++R GPP + AQV +  ++++I+NS+ I 
Sbjct: 61  GVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQ 120

Query: 121 LKDLCIVPDKLAWVVYCDMVCIDHDGSLVDACIIALIASFKTLLLPSVNYDTETEEIKVE 180
            +DLCI P KL WV+YCD++C+D+DG+++DAC  AL+A+ K + LP V  + ET   +V 
Sbjct: 121 KEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVN 180

Query: 181 TNERINLKIHGLPVATSFAVYEHFQSQIILLTDPTNYEEEMCGGNGSNLIISYNKGLLCG 240
             ++  L I   PVATSFAV++      +L+ DPT  EE +    G+  I+   +G LC 
Sbjct: 181 LKKKSYLNIRTHPVATSFAVFD----DTLLIVDPTGEEEHL--ATGTLTIVMDEEGKLCC 234

Query: 241 IQKLGGGSLSTENNEEAIRLAEQHTIAVEKRLSKI 275
           + K GG  L+    ++ +  A      V+K + ++
Sbjct: 235 LHKPGGSGLTGAKLQDCMSRAVTRHKEVKKLMDEV 269


>AF025438-1|AAC39558.1|  265|Homo sapiens Opa-interacting protein
           OIP2 protein.
          Length = 265

 Score =  232 bits (568), Expect = 3e-60
 Identities = 108/266 (40%), Positives = 166/266 (62%), Gaps = 6/266 (2%)

Query: 5   YKLIHPVKHFNDYISIKTRLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKL 64
           +K + P++++  ++    R DGR   E R   +N+ SI TAD SA+VK GNTTV+CG+K 
Sbjct: 3   FKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKA 62

Query: 65  ELAVPKAEEPDLGFLITNVELPALCSSKYRPGPPSDYAQVINNIVSEIIKNSKCIDLKDL 124
           E A P  + PD G+++ NV+LP LCSS++R GPP + AQV +  ++++I+NS+ I  +DL
Sbjct: 63  EFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDL 122

Query: 125 CIVPDKLAWVVYCDMVCIDHDGSLVDACIIALIASFKTLLLPSVNYDTETEEIKVETNER 184
           CI P KL WV+YCD++C+D+DG+++DAC  AL+A+ K + LP V  + ET   +V   ++
Sbjct: 123 CISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVNLKKK 182

Query: 185 INLKIHGLPVATSFAVYEHFQSQIILLTDPTNYEEEMCGGNGSNLIISYNKGLLCGIQKL 244
             L I   PVATSFAV++      +L+ DPT  EE +    G+  I+   +G LC + K 
Sbjct: 183 SYLNIRTHPVATSFAVFD----DTLLIVDPTGEEEHL--ATGTLTIVMDEEGKLCCLHKP 236

Query: 245 GGGSLSTENNEEAIRLAEQHTIAVEK 270
           GG  L+    ++ +  A      V+K
Sbjct: 237 GGSGLTGAKLQDCMSRAVTRHKEVKK 262


>AL138706-8|CAI14013.1|  275|Homo sapiens RP11-421P11.3 protein.
          Length = 275

 Score =  230 bits (563), Expect = 1e-59
 Identities = 109/275 (39%), Positives = 170/275 (61%), Gaps = 7/275 (2%)

Query: 1   MSEVYKLIHPVKHFNDYISIKTRLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVC 60
           M+  +K + P++++  ++    R DGR   E R   +N+ SI TAD SA+VK GNTTV+C
Sbjct: 1   MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVIC 60

Query: 61  GIKLELAVPKAEEPDLGFLITNVELPALCSSKYRPGPPSDYAQVINNIVSEIIKNSKCID 120
           G+K E A P  + PD G+++ NV+LP LCSS++R GPP + AQV +  ++++I+NS+ I 
Sbjct: 61  GVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQ 120

Query: 121 LKDLCIVPDKLAWVVYCDMVCIDHDGSLVDACIIALIASFKTLLLPSVNYDTETEEIKVE 180
            +DLCI P KL WV+YCD++C+D+DG+++DAC  AL+A+ K + LP V  + ET   +V 
Sbjct: 121 KEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVN 180

Query: 181 TNERINLKIHGLPVATSFAVYEHFQSQIILLTDPTNYEEEMCGGNGSNLIISYNKGLLCG 240
             ++  L I   PVATSFAV++      +L+ DPT  EE +    G+  I+   +G LC 
Sbjct: 181 LKKKSYLNIRTHPVATSFAVFD----DTLLIVDPTGEEEHL--ATGTLTIVMDEEGKLCC 234

Query: 241 IQKLGGGSLSTENNEEAIRLAEQHTIAVEKRLSKI 275
           + K G G    +  +   R   +H   V+K + ++
Sbjct: 235 LHKPGIGLTGAKLQDCMSRAVTRHK-EVKKLMDEV 268


>AJ517294-1|CAD56889.1|  456|Homo sapiens polymyositis/scleroderma
           autoantigen 1 protein.
          Length = 456

 Score =  128 bits (308), Expect = 1e-28
 Identities = 78/231 (33%), Positives = 115/231 (49%), Gaps = 11/231 (4%)

Query: 18  ISIKTRLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKLELAVPKAEEPDLG 77
           I  K RLDGR   ++RNI++   S  T     +V+ G T V+  +  EL  PK      G
Sbjct: 18  IEEKKRLDGRQTYDYRNIRI---SFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEG 74

Query: 78  FLITNVELPALCSSKYRPGPPSDYAQVINNIVSEIIKNSKCIDLKDLCIVPDKLAWVVYC 137
            L  N+EL  + +  + PG  SD    +N ++   ++NSKCID + LC+V  +  W +  
Sbjct: 75  ILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRV 134

Query: 138 DMVCIDHDGSLVDACIIALIASFKTLLLPSVNYD-TETEEIKVETNERINLKIHGLPVAT 196
           D+  ++HDG+++DA  IA I +      P V+    E      E  + + L IH +P+  
Sbjct: 135 DLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICV 194

Query: 197 SFAVYEHFQSQIILLTDPTNYEEEMCGGNGSNLIISYNKGL-LCGIQKLGG 246
           SFA    FQ    LL DP   EE +  G    L+I+ NK   +C IQ  GG
Sbjct: 195 SFA---FFQQGTYLLVDPNEREERVMDG---LLVIAMNKHREICTIQSSGG 239


>AJ505989-1|CAD44530.1|  439|Homo sapiens polymyositis/scleroderma
           autoantigen 1 protein.
          Length = 439

 Score =  128 bits (308), Expect = 1e-28
 Identities = 78/231 (33%), Positives = 115/231 (49%), Gaps = 11/231 (4%)

Query: 18  ISIKTRLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKLELAVPKAEEPDLG 77
           I  K RLDGR   ++RNI++   S  T     +V+ G T V+  +  EL  PK      G
Sbjct: 18  IEEKKRLDGRQTYDYRNIRI---SFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEG 74

Query: 78  FLITNVELPALCSSKYRPGPPSDYAQVINNIVSEIIKNSKCIDLKDLCIVPDKLAWVVYC 137
            L  N+EL  + +  + PG  SD    +N ++   ++NSKCID + LC+V  +  W +  
Sbjct: 75  ILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRV 134

Query: 138 DMVCIDHDGSLVDACIIALIASFKTLLLPSVNYD-TETEEIKVETNERINLKIHGLPVAT 196
           D+  ++HDG+++DA  IA I +      P V+    E      E  + + L IH +P+  
Sbjct: 135 DLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICV 194

Query: 197 SFAVYEHFQSQIILLTDPTNYEEEMCGGNGSNLIISYNKGL-LCGIQKLGG 246
           SFA    FQ    LL DP   EE +  G    L+I+ NK   +C IQ  GG
Sbjct: 195 SFA---FFQQGTYLLVDPNEREERVMDG---LLVIAMNKHREICTIQSSGG 239


>D29958-1|BAA06226.1|  290|Homo sapiens KIAA0116 protein.
          Length = 290

 Score =  105 bits (253), Expect = 5e-22
 Identities = 69/238 (28%), Positives = 119/238 (50%), Gaps = 16/238 (6%)

Query: 23  RLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKLELAVPKAEEPDLGFLITN 82
           R+DGR  +++R +++  + +     SA VK G+T ++ G+K E+  PK E+P+ G+L   
Sbjct: 22  RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFF 81

Query: 83  VELPALCSSKYRPGPPSDYAQVINNIVSEIIKNSKCIDLKDLCIVPDKLAWVVYCDMVCI 142
           V+  A  + ++      D    I N +  I  N   +DLK LCI P +  WV+Y D++ +
Sbjct: 82  VDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVLLL 141

Query: 143 DHDGSLVDACIIALIASFKTLLLPSVNYDTETE-----EIKVETNERINLKIHGLPVATS 197
           +  G+L DA  IA+ A+     +P V    + E     E+  +  + I L +  +P   +
Sbjct: 142 ECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVT 201

Query: 198 FAV--YEHFQSQIILLTDPTNYEEEMCGGNGSNLIISYNKGLLCGIQKLGGGSLSTEN 253
                Y H       + D T  +EE C    S L+   +KG++  ++K+G GSL  E+
Sbjct: 202 LCKIGYRH-------VVDAT-LQEEAC-SLASLLVSVTSKGVVTCMRKVGKGSLDPES 250


>BC012831-1|AAH12831.1|  291|Homo sapiens exosome component 7
           protein.
          Length = 291

 Score =  105 bits (253), Expect = 5e-22
 Identities = 69/238 (28%), Positives = 119/238 (50%), Gaps = 16/238 (6%)

Query: 23  RLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKLELAVPKAEEPDLGFLITN 82
           R+DGR  +++R +++  + +     SA VK G+T ++ G+K E+  PK E+P+ G+L   
Sbjct: 23  RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFF 82

Query: 83  VELPALCSSKYRPGPPSDYAQVINNIVSEIIKNSKCIDLKDLCIVPDKLAWVVYCDMVCI 142
           V+  A  + ++      D    I N +  I  N   +DLK LCI P +  WV+Y D++ +
Sbjct: 83  VDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVLLL 142

Query: 143 DHDGSLVDACIIALIASFKTLLLPSVNYDTETE-----EIKVETNERINLKIHGLPVATS 197
           +  G+L DA  IA+ A+     +P V    + E     E+  +  + I L +  +P   +
Sbjct: 143 ECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVT 202

Query: 198 FAV--YEHFQSQIILLTDPTNYEEEMCGGNGSNLIISYNKGLLCGIQKLGGGSLSTEN 253
                Y H       + D T  +EE C    S L+   +KG++  ++K+G GSL  E+
Sbjct: 203 LCKIGYRH-------VVDAT-LQEEAC-SLASLLVSVTSKGVVTCMRKVGKGSLDPES 251


>U09215-1|AAA18832.1|  372|Homo sapiens PM-Scl-75 autoantigen
           protein.
          Length = 372

 Score = 92.3 bits (219), Expect = 6e-18
 Identities = 53/161 (32%), Positives = 81/161 (50%), Gaps = 8/161 (4%)

Query: 88  LCSSKYRPGPPSDYAQVINNIVSEIIKNSKCIDLKDLCIVPDKLAWVVYCDMVCIDHDGS 147
           + +  + PG  SD    +N ++   ++NSKCID + LC+V  +  W +  D+  ++HDG+
Sbjct: 1   MAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGN 60

Query: 148 LVDACIIALIASFKTLLLPSVNYD-TETEEIKVETNERINLKIHGLPVATSFAVYEHFQS 206
           ++DA  IA I +      P V+    E      E  + + L IH +P+  SFA    FQ 
Sbjct: 61  IIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFA---FFQQ 117

Query: 207 QIILLTDPTNYEEEMCGGNGSNLIISYNKGL-LCGIQKLGG 246
              LL DP   EE +  G    L+I+ NK   +C IQ  GG
Sbjct: 118 GTYLLVDPNEREERVMDG---LLVIAMNKHREICTIQSSGG 155


>M58460-1|AAA58384.1|  355|Homo sapiens autoantigen protein.
          Length = 355

 Score = 92.3 bits (219), Expect = 6e-18
 Identities = 53/161 (32%), Positives = 81/161 (50%), Gaps = 8/161 (4%)

Query: 88  LCSSKYRPGPPSDYAQVINNIVSEIIKNSKCIDLKDLCIVPDKLAWVVYCDMVCIDHDGS 147
           + +  + PG  SD    +N ++   ++NSKCID + LC+V  +  W +  D+  ++HDG+
Sbjct: 1   MAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGN 60

Query: 148 LVDACIIALIASFKTLLLPSVNYD-TETEEIKVETNERINLKIHGLPVATSFAVYEHFQS 206
           ++DA  IA I +      P V+    E      E  + + L IH +P+  SFA    FQ 
Sbjct: 61  IIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFA---FFQQ 117

Query: 207 QIILLTDPTNYEEEMCGGNGSNLIISYNKGL-LCGIQKLGG 246
              LL DP   EE +  G    L+I+ NK   +C IQ  GG
Sbjct: 118 GTYLLVDPNEREERVMDG---LLVIAMNKHREICTIQSSGG 155


>AC079341-2|AAY40968.1|  355|Homo sapiens unknown protein.
          Length = 355

 Score = 92.3 bits (219), Expect = 6e-18
 Identities = 53/161 (32%), Positives = 81/161 (50%), Gaps = 8/161 (4%)

Query: 88  LCSSKYRPGPPSDYAQVINNIVSEIIKNSKCIDLKDLCIVPDKLAWVVYCDMVCIDHDGS 147
           + +  + PG  SD    +N ++   ++NSKCID + LC+V  +  W +  D+  ++HDG+
Sbjct: 1   MAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGN 60

Query: 148 LVDACIIALIASFKTLLLPSVNYD-TETEEIKVETNERINLKIHGLPVATSFAVYEHFQS 206
           ++DA  IA I +      P V+    E      E  + + L IH +P+  SFA    FQ 
Sbjct: 61  IIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFA---FFQQ 117

Query: 207 QIILLTDPTNYEEEMCGGNGSNLIISYNKGL-LCGIQKLGG 246
              LL DP   EE +  G    L+I+ NK   +C IQ  GG
Sbjct: 118 GTYLLVDPNEREERVMDG---LLVIAMNKHREICTIQSSGG 155


>BC067904-1|AAH67904.1|  142|Homo sapiens similar to RIKEN cDNA
           2700038N03 protein.
          Length = 142

 Score = 83.0 bits (196), Expect = 4e-15
 Identities = 48/130 (36%), Positives = 63/130 (48%), Gaps = 5/130 (3%)

Query: 673 IGDKQSTFIGSKQWIGSTEVMFCLETLLGVQSRIIFANTGTELQSYAPELVHHFQTHGSP 732
           +GDK   F GS+ WIG  E   CL    G Q R+     G  L      L  HF   G P
Sbjct: 1   MGDKPPGFRGSRDWIGCVEASLCLAHFGGPQGRLCHVPRGVGLHGEVERLYSHFAGGGGP 60

Query: 733 IMIGGGVLAHT--ILGIEYNSITNETRYLILDPHYTGAEDITTVIN-KGWCGWKS-SDFW 788
           +M+GG   A +  +LG+   S T E   L+LDPHY G     + +   GW GW+  S  +
Sbjct: 61  VMVGGDADARSKALLGVCVGSGT-EAYVLVLDPHYWGTPKSPSELQAAGWVGWQEVSAAF 119

Query: 789 NKTAHYNLCL 798
           +  + YNLCL
Sbjct: 120 DPNSFYNLCL 129


>AF312032-2|AAK21004.1|  142|Homo sapiens unknown protein.
          Length = 142

 Score = 82.6 bits (195), Expect = 5e-15
 Identities = 48/130 (36%), Positives = 63/130 (48%), Gaps = 5/130 (3%)

Query: 673 IGDKQSTFIGSKQWIGSTEVMFCLETLLGVQSRIIFANTGTELQSYAPELVHHFQTHGSP 732
           +GDK   F GS+ WIG  E   CL    G Q R+     G  L      L  HF   G P
Sbjct: 1   MGDKPPGFRGSRDWIGCVEASLCLAHFGGPQGRLCHVPRGVGLHGELERLYSHFAGGGGP 60

Query: 733 IMIGGGVLAHT--ILGIEYNSITNETRYLILDPHYTGAEDITTVIN-KGWCGWKS-SDFW 788
           +M+GG   A +  +LG+   S T E   L+LDPHY G     + +   GW GW+  S  +
Sbjct: 61  VMVGGDADARSKALLGVCVGSGT-EAYVLVLDPHYWGTPKSPSELQAAGWVGWQEVSAAF 119

Query: 789 NKTAHYNLCL 798
           +  + YNLCL
Sbjct: 120 DPNSFYNLCL 129


>BC053660-1|AAH53660.1|  783|Homo sapiens polyribonucleotide
           nucleotidyltransferase 1 protein.
          Length = 783

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 15/43 (34%), Positives = 23/43 (53%)

Query: 23  RLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKLE 65
           R DGR+    RN+   V+  KT   SA+ + G T V+C +  +
Sbjct: 358 RCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFD 400


>AY027528-1|AAK13047.1|  783|Homo sapiens 3'-5' RNA exonuclease
           protein.
          Length = 783

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 15/43 (34%), Positives = 23/43 (53%)

Query: 23  RLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKLE 65
           R DGR+    RN+   V+  KT   SA+ + G T V+C +  +
Sbjct: 358 RCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFD 400


>AK027437-1|BAB55109.1|  504|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14531 fis, clone NT2RM2000371, weakly similar to
           POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE (EC 2.7.7.8).
           ).
          Length = 504

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 15/43 (34%), Positives = 23/43 (53%)

Query: 23  RLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKLE 65
           R DGR+    RN+   V+  KT   SA+ + G T V+C +  +
Sbjct: 358 RCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFD 400


>AJ458465-1|CAD30289.1|  783|Homo sapiens polynucleotide
           phosphorylase-like protein protein.
          Length = 783

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 15/43 (34%), Positives = 23/43 (53%)

Query: 23  RLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKLE 65
           R DGR+    RN+   V+  KT   SA+ + G T V+C +  +
Sbjct: 358 RCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFD 400


>AC015982-3|AAY24271.1|  783|Homo sapiens unknown protein.
          Length = 783

 Score = 34.3 bits (75), Expect = 1.7
 Identities = 15/43 (34%), Positives = 23/43 (53%)

Query: 23  RLDGRNFDEHRNIKLNVNSIKTADASAVVKCGNTTVVCGIKLE 65
           R DGR+    RN+   V+  KT   SA+ + G T V+C +  +
Sbjct: 358 RCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFD 400


>BX537872-1|CAD97873.1|  578|Homo sapiens hypothetical protein
           protein.
          Length = 578

 Score = 33.9 bits (74), Expect = 2.3
 Identities = 30/97 (30%), Positives = 44/97 (45%), Gaps = 16/97 (16%)

Query: 626 YMQDNFNDDGWGCAYRSMQTIFS-WFRYQGYTD----VEVPTHKEIQQCLV---KIG-DK 676
           +   +  D GWGC YR+ Q + S   +   Y D    + +P   +IQ  +    K G D 
Sbjct: 348 HFHSSLGDKGWGCGYRNFQMLLSSLLQNDAYNDCLKGMLIPCIPKIQSMIEDAWKEGFDP 407

Query: 677 QST------FIGSKQWIGSTEVMFCLETLLGVQSRII 707
           Q          G+K WIG+ EV + L T L V+  I+
Sbjct: 408 QGASQLNNRLQGTKAWIGACEV-YILLTSLRVKCHIV 443


>BC016879-1|AAH16879.1|  578|Homo sapiens chromosome 6 open reading
           frame 113 protein.
          Length = 578

 Score = 33.9 bits (74), Expect = 2.3
 Identities = 30/97 (30%), Positives = 44/97 (45%), Gaps = 16/97 (16%)

Query: 626 YMQDNFNDDGWGCAYRSMQTIFS-WFRYQGYTD----VEVPTHKEIQQCLV---KIG-DK 676
           +   +  D GWGC YR+ Q + S   +   Y D    + +P   +IQ  +    K G D 
Sbjct: 348 HFHSSLGDKGWGCGYRNFQMLLSSLLQNDAYNDCLKGMLIPCIPKIQSMIEDAWKEGFDP 407

Query: 677 QST------FIGSKQWIGSTEVMFCLETLLGVQSRII 707
           Q          G+K WIG+ EV + L T L V+  I+
Sbjct: 408 QGASQLNNRLQGTKAWIGACEV-YILLTSLRVKCHIV 443


>AL132795-3|CAI20498.1|  578|Homo sapiens RP3-412I7.3 protein.
          Length = 578

 Score = 33.9 bits (74), Expect = 2.3
 Identities = 30/97 (30%), Positives = 44/97 (45%), Gaps = 16/97 (16%)

Query: 626 YMQDNFNDDGWGCAYRSMQTIFS-WFRYQGYTD----VEVPTHKEIQQCLV---KIG-DK 676
           +   +  D GWGC YR+ Q + S   +   Y D    + +P   +IQ  +    K G D 
Sbjct: 348 HFHSSLGDKGWGCGYRNFQMLLSSLLQNDAYNDCLKGMLIPCIPKIQSMIEDAWKEGFDP 407

Query: 677 QST------FIGSKQWIGSTEVMFCLETLLGVQSRII 707
           Q          G+K WIG+ EV + L T L V+  I+
Sbjct: 408 QGASQLNNRLQGTKAWIGACEV-YILLTSLRVKCHIV 443


>AK054582-1|BAB70765.1|  578|Homo sapiens protein ( Homo sapiens
           cDNA FLJ30020 fis, clone 3NB692000912. ).
          Length = 578

 Score = 33.5 bits (73), Expect = 3.0
 Identities = 30/97 (30%), Positives = 44/97 (45%), Gaps = 16/97 (16%)

Query: 626 YMQDNFNDDGWGCAYRSMQTIFS-WFRYQGYTD----VEVPTHKEIQQCLV---KIG-DK 676
           +   +  D GWGC YR+ Q + S   +   Y D    + +P   +IQ  +    K G D 
Sbjct: 348 HFHSSLGDKGWGCGYRNFQMLLSSLLQNDAYDDCLKGMLIPCIPKIQSMIEDAWKEGFDP 407

Query: 677 QST------FIGSKQWIGSTEVMFCLETLLGVQSRII 707
           Q          G+K WIG+ EV + L T L V+  I+
Sbjct: 408 QGASQLNNRLQGTKAWIGACEV-YILLTSLRVKCHIV 443


>X52022-1|CAA36267.1| 3176|Homo sapiens collagen type VI, alpha 3
            chain protein.
          Length = 3176

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 473  KKYNI-NNAEILPVSLILKVTKDILSDKLVKTAVKMMTTQRKPAFYISMP 521
            K+ N+ NN    P S  +  TK + + K V T  K +TT  KP   I+ P
Sbjct: 2854 KQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQP 2903


>BX641155-1|CAE46068.1|  558|Homo sapiens hypothetical protein
           protein.
          Length = 558

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 473 KKYNI-NNAEILPVSLILKVTKDILSDKLVKTAVKMMTTQRKPAFYISMP 521
           K+ N+ NN    P S  +  TK + + K V T  K +TT  KP   I+ P
Sbjct: 235 KQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQP 284


>BC071564-1|AAH71564.1| 1224|Homo sapiens bromodomain and WD repeat
           domain containing 2 protein.
          Length = 1224

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 744 ILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNLCLPQTRP 803
           +L  + NS++N+ + L+LDP +T  +    ++++ +       FW   AHY   L Q + 
Sbjct: 886 LLQEQLNSLSNDIKKLLLDPEFTLLQR-CLLVSRLYGDESELHFWTVAAHYLHSLSQEKS 944

Query: 804 A 804
           A
Sbjct: 945 A 945


>BC040469-1|AAH40469.1| 1224|Homo sapiens bromodomain and WD repeat
           domain containing 2 protein.
          Length = 1224

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 744 ILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNLCLPQTRP 803
           +L  + NS++N+ + L+LDP +T  +    ++++ +       FW   AHY   L Q + 
Sbjct: 886 LLQEQLNSLSNDIKKLLLDPEFTLLQR-CLLVSRLYGDESELHFWTVAAHYLHSLSQEKS 944

Query: 804 A 804
           A
Sbjct: 945 A 945


>BC033174-1|AAH33174.1|  979|Homo sapiens Similar to collagen, type
           VI, alpha 3 protein.
          Length = 979

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 473 KKYNI-NNAEILPVSLILKVTKDILSDKLVKTAVKMMTTQRKPAFYISMP 521
           K+ N+ NN    P S  +  TK + + K V T  K +TT  KP   I+ P
Sbjct: 656 KQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQP 705


>AL391425-1|CAH72488.1| 1224|Homo sapiens WD repeat domain 11
           protein.
          Length = 1224

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 744 ILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNLCLPQTRP 803
           +L  + NS++N+ + L+LDP +T  +    ++++ +       FW   AHY   L Q + 
Sbjct: 886 LLQEQLNSLSNDIKKLLLDPEFTLLQR-CLLVSRLYGDESELHFWTVAAHYLHSLSQEKS 944

Query: 804 A 804
           A
Sbjct: 945 A 945


>AK001368-1|BAA91652.1|  864|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10506 fis, clone NT2RP2000510. ).
          Length = 864

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 744 ILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNLCLPQTRP 803
           +L  + NS++N+ + L+LDP +T  +    ++++ +       FW   AHY   L Q + 
Sbjct: 526 LLQEQLNSLSNDIKKLLLDPEFTLLQR-CLLVSRLYGDESELHFWTVAAHYLHSLSQEKS 584

Query: 804 A 804
           A
Sbjct: 585 A 585


>AK000579-1|BAA91269.1|  515|Homo sapiens protein ( Homo sapiens
           cDNA FLJ20572 fis, clone REC01048. ).
          Length = 515

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 744 ILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNLCLPQTRP 803
           +L  + NS++N+ + L+LDP +T  +    ++++ +       FW   AHY   L Q + 
Sbjct: 177 LLQEQLNSLSNDIKKLLLDPEFTLLQR-CLLVSRLYGDESELHFWTVAAHYLHSLSQEKS 235

Query: 804 A 804
           A
Sbjct: 236 A 236


>AF320223-1|AAK08064.1| 1224|Homo sapiens WD40 repeat domain 11
           protein protein.
          Length = 1224

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 744 ILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNLCLPQTRP 803
           +L  + NS++N+ + L+LDP +T  +    ++++ +       FW   AHY   L Q + 
Sbjct: 886 LLQEQLNSLSNDIKKLLLDPEFTLLQR-CLLVSRLYGDESELHFWTVAAHYLHSLSQEKS 944

Query: 804 A 804
           A
Sbjct: 945 A 945


>AC112715-1|AAY14906.1|  588|Homo sapiens unknown protein.
          Length = 588

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 473 KKYNI-NNAEILPVSLILKVTKDILSDKLVKTAVKMMTTQRKPAFYISMP 521
           K+ N+ NN    P S  +  TK + + K V T  K +TT  KP   I+ P
Sbjct: 265 KQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQP 314


>AB209636-1|BAD92873.1| 1702|Homo sapiens alpha 3 type VI collagen
            isoform 5 precursor variant protein.
          Length = 1702

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 473  KKYNI-NNAEILPVSLILKVTKDILSDKLVKTAVKMMTTQRKPAFYISMP 521
            K+ N+ NN    P S  +  TK + + K V T  K +TT  KP   I+ P
Sbjct: 1379 KQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTTKPVTIINQP 1428


>AB037772-1|BAA92589.2| 1243|Homo sapiens KIAA1351 protein protein.
          Length = 1243

 Score = 31.9 bits (69), Expect = 9.3
 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 744 ILGIEYNSITNETRYLILDPHYTGAEDITTVINKGWCGWKSSDFWNKTAHYNLCLPQTRP 803
           +L  + NS++N+ + L+LDP +T  +    ++++ +       FW   AHY   L Q + 
Sbjct: 905 LLQEQLNSLSNDIKKLLLDPEFTLLQR-CLLVSRLYGDESELHFWTVAAHYLHSLSQEKS 963

Query: 804 A 804
           A
Sbjct: 964 A 964


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.319    0.135    0.400 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,952,392
Number of Sequences: 224733
Number of extensions: 4940178
Number of successful extensions: 9375
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 9324
Number of HSP's gapped (non-prelim): 54
length of query: 805
length of database: 73,234,838
effective HSP length: 96
effective length of query: 709
effective length of database: 51,660,470
effective search space: 36627273230
effective search space used: 36627273230
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 69 (31.9 bits)

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