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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001185-TA|BGIBMGA001185-PA|IPR011059|Metal-dependent
hydrolase, composite, IPR003764|N-acetylglucosamine-6-phosphate
deacetylase, IPR006680|Amidohydrolase 1
         (398 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AF132948-1|AAD27723.1|  404|Homo sapiens CGI-14 protein protein.      384   e-106
BC018734-1|AAH18734.1|  439|Homo sapiens amidohydrolase domain c...   353   8e-97
AB209351-1|BAD92588.1|  192|Homo sapiens CGI-14 protein variant ...   144   4e-34
X01179-1|CAA25619.1| 2351|Homo sapiens protein ( Human mRNA for ...    32   4.1  
M88648-1|AAA52420.1| 2351|Homo sapiens coagulation factor VIII p...    32   4.1  
M14113-1|AAA52485.1| 2351|Homo sapiens F8C protein.                    32   4.1  
K01740-1|AAA52484.1| 2351|Homo sapiens F8C protein.                    32   4.1  
BX890586-1|CAI43241.1| 2351|Homo sapiens coagulation factor VIII...    32   4.1  
BX842564-2|CAI41666.1| 2351|Homo sapiens coagulation factor VIII...    32   4.1  
BX842559-6|CAI41672.1| 2351|Homo sapiens coagulation factor VIII...    32   4.1  
BX470111-8|CAI41660.1| 2351|Homo sapiens coagulation factor VIII...    32   4.1  
AY769950-1|AAV85964.1| 2351|Homo sapiens coagulation factor VIII...    32   4.1  
BC000059-1|AAH00059.2|  771|Homo sapiens CELSR1 protein protein.       31   9.4  
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven...    31   9.4  
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven...    31   9.4  
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven...    31   9.4  
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ...    31   9.4  

>AF132948-1|AAD27723.1|  404|Homo sapiens CGI-14 protein protein.
          Length = 404

 Score =  384 bits (946), Expect = e-106
 Identities = 196/391 (50%), Positives = 270/391 (69%), Gaps = 9/391 (2%)

Query: 9   RFHNCYILRDRKIIKEDLWIRDGKIENPERVFYVEQLESDITVDCEDLLIAPGFIDIQIN 68
           +F NC ILR  K+++EDLW+R G+I +PE++F+ E+  +D   DC   ++APGFID+QIN
Sbjct: 13  QFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGGRILAPGFIDVQIN 72

Query: 69  GGWGVDFSRDSDNIEEGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKN 128
           GG+GVDFS+ ++++  GVA VA+ +L+HG     P   +    +Y +++P+I    G  +
Sbjct: 73  GGFGVDFSQATEDVGSGVALVAREILSHGSPPSAPPW-SLPTGVYHKVVPQIPVKSGGPH 131

Query: 129 GATVLGVHLEGPFISPTKKGAHVESYIKNPHR-GIDTIREVYGSLDNVVIITLAPELPGC 187
           G  VLG+HLEGPFIS  K+G H E+++++        +   YG LDNV I+TLAPEL G 
Sbjct: 132 GQGVLGLHLEGPFISREKRGTHPEAHLRSFEADAFQDLLATYGPLDNVRIVTLAPEL-GV 190

Query: 188 FEAIKDLTNLGIKVALGHSIASLAEGEKAVECGANLITHLFNAMLPFHHRDPGLVGLLAS 247
              ++ LT   I V+LGHS+A L   E AV  G   ITHLFNAMLPFHHRDPG+VGLL S
Sbjct: 191 ARVLRALT-AWICVSLGHSVADLRAAEDAVWSGT-FITHLFNAMLPFHHRDPGIVGLLTS 248

Query: 248 TMK---KQVYYGIIADGIHTHPAALRIANRTNPEGLVLVSDAVPAQGLPDGNHRIGPQIV 304
                 + ++YG+IADG HT+PAALRIA+R +P+GLVLV+DA+PA GL +G H +G Q V
Sbjct: 249 DRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALGLGNGRHTLGQQEV 308

Query: 305 TVEDGCAYVTGTKTLCGSTTALDSCIVKFKDSIECSLEYALEAASLHPAKALGIDDKKGN 364
            V+   AYV GTKTL GS   +D C+  F  +  CS+E ALEAASLHPA+ LG++  KG 
Sbjct: 309 EVDGLTAYVAGTKTLSGSIAPMDVCVRHFLQATGCSMESALEAASLHPAQLLGLEKSKGT 368

Query: 365 LNFDSDADFVILHPKTLKVQSTWIAGECVYK 395
           L+F +DADFV+L   +L VQ+T+I+GE V++
Sbjct: 369 LDFGADADFVVL-DDSLHVQATYISGELVWQ 398


>BC018734-1|AAH18734.1|  439|Homo sapiens amidohydrolase domain
           containing 2 protein.
          Length = 439

 Score =  353 bits (867), Expect = 8e-97
 Identities = 196/421 (46%), Positives = 264/421 (62%), Gaps = 35/421 (8%)

Query: 9   RFHNCYILRDRKIIKEDLWIRDGKIENPERVFYVEQLESDITVDCEDLLIAPGFIDIQIN 68
           +F NC ILR  K+++EDLW+R G+I +PE++F+ E+  +D   DC   ++APGFID+QIN
Sbjct: 14  QFTNCRILRGGKLLREDLWVRGGRILDPEKLFFEERRVADERRDCGGRILAPGFIDVQIN 73

Query: 69  GGWGVDFSRDSDNIEEGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKN 128
           GG+GVDFS+ ++++  GVA VA+ +L+HGVT+FCPT++TS  E+Y +++P+I    G  +
Sbjct: 74  GGFGVDFSQATEDVGSGVALVARRILSHGVTSFCPTLVTSPPEVYHKVVPQIPVKSGGPH 133

Query: 129 GATVLGVHLEGPFISPTKKGAHVESYIKNPHR-GIDTIREVYGSLDNVVIITLAPELPGC 187
           GA VLG+HLEGPFIS  K+GAH E+++++        +   YG LDNV I+TLAPEL   
Sbjct: 134 GAGVLGLHLEGPFISREKRGAHPEAHLRSFEADAFQDLLATYGPLDNVRIVTLAPELGRS 193

Query: 188 FEAIKDLTNLGIKVALGHSIASLAEGEKAVECGANLITHLFNAMLPFHHRDPGLVGLLAS 247
            E I+ LT  GI V+LGHS+A L   E AV  GA  ITHLFNAMLPFHHRDPG+VGLL S
Sbjct: 194 HEVIRALTARGICVSLGHSVADLRAAEDAVWSGATFITHLFNAMLPFHHRDPGIVGLLTS 253

Query: 248 TMK---KQVYYGIIADGIHT-----------HPAALRIANRTNPE-GL-----VLVSDAV 287
                 + ++YG+IADG HT           HP  L +     P  GL      L    V
Sbjct: 254 DRLPAGRCIFYGMIADGTHTNPAALRIAHRAHPQGLVLVTDAIPALGLGNGRHTLGQQEV 313

Query: 288 PAQGL--------PDG-NHRIGPQIVTVED---GCAYVT-GTKTLCGSTTALDSCIVKFK 334
              GL        PD    R  P      D    C   + GTKTL GS   +D C+  F 
Sbjct: 314 EVDGLTAYVAGERPDPLGPRSQPACQVAHDPPRACPLCSQGTKTLSGSIAPMDVCVRHFL 373

Query: 335 DSIECSLEYALEAASLHPAKALGIDDKKGNLNFDSDADFVILHPKTLKVQSTWIAGECVY 394
            +  CS+E ALEAASLHPA+ LG++  KG L+F +DADFV+L   +L VQ+T+I+GE V+
Sbjct: 374 QATGCSMESALEAASLHPAQLLGLEKSKGTLDFGADADFVVL-DDSLHVQATYISGELVW 432

Query: 395 K 395
           +
Sbjct: 433 Q 433


>AB209351-1|BAD92588.1|  192|Homo sapiens CGI-14 protein variant
           protein.
          Length = 192

 Score =  144 bits (350), Expect = 4e-34
 Identities = 70/117 (59%), Positives = 86/117 (73%), Gaps = 3/117 (2%)

Query: 204 GHSIASLAEGEKAVECGANLITHLFNAMLPFHHRDPGLVGLLASTMK---KQVYYGIIAD 260
           GHS+A L   E AV  GA  ITHLFNAMLPFHHRDPG+VGLL S      + ++YG+IAD
Sbjct: 24  GHSVADLRAAEDAVWSGATFITHLFNAMLPFHHRDPGIVGLLTSDRLPAGRCIFYGMIAD 83

Query: 261 GIHTHPAALRIANRTNPEGLVLVSDAVPAQGLPDGNHRIGPQIVTVEDGCAYVTGTK 317
           G HT+PAALRIA+R +P+GLVLV+DA+PA GL +G H +G Q V V+   AYV G +
Sbjct: 84  GTHTNPAALRIAHRAHPQGLVLVTDAIPALGLGNGRHTLGQQEVEVDGLTAYVAGER 140


>X01179-1|CAA25619.1| 2351|Homo sapiens protein ( Human mRNA for
            factor VIII. ).
          Length = 2351

 Score = 31.9 bits (69), Expect = 4.1
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 84   EGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGP 140
            + V+      L  G  A  P ++T D  +++  +  +K  + + N AT    H++GP
Sbjct: 981  KNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGP 1037


>M88648-1|AAA52420.1| 2351|Homo sapiens coagulation factor VIII
            protein.
          Length = 2351

 Score = 31.9 bits (69), Expect = 4.1
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 84   EGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGP 140
            + V+      L  G  A  P ++T D  +++  +  +K  + + N AT    H++GP
Sbjct: 981  KNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGP 1037


>M14113-1|AAA52485.1| 2351|Homo sapiens F8C protein.
          Length = 2351

 Score = 31.9 bits (69), Expect = 4.1
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 84   EGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGP 140
            + V+      L  G  A  P ++T D  +++  +  +K  + + N AT    H++GP
Sbjct: 981  KNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGP 1037


>K01740-1|AAA52484.1| 2351|Homo sapiens F8C protein.
          Length = 2351

 Score = 31.9 bits (69), Expect = 4.1
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 84   EGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGP 140
            + V+      L  G  A  P ++T D  +++  +  +K  + + N AT    H++GP
Sbjct: 981  KNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGP 1037


>BX890586-1|CAI43241.1| 2351|Homo sapiens coagulation factor VIII,
            procoagulant component (hemophilia A) protein.
          Length = 2351

 Score = 31.9 bits (69), Expect = 4.1
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 84   EGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGP 140
            + V+      L  G  A  P ++T D  +++  +  +K  + + N AT    H++GP
Sbjct: 981  KNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGP 1037


>BX842564-2|CAI41666.1| 2351|Homo sapiens coagulation factor VIII,
            procoagulant component (hemophilia A) protein.
          Length = 2351

 Score = 31.9 bits (69), Expect = 4.1
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 84   EGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGP 140
            + V+      L  G  A  P ++T D  +++  +  +K  + + N AT    H++GP
Sbjct: 981  KNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGP 1037


>BX842559-6|CAI41672.1| 2351|Homo sapiens coagulation factor VIII,
            procoagulant component (hemophilia A) protein.
          Length = 2351

 Score = 31.9 bits (69), Expect = 4.1
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 84   EGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGP 140
            + V+      L  G  A  P ++T D  +++  +  +K  + + N AT    H++GP
Sbjct: 981  KNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGP 1037


>BX470111-8|CAI41660.1| 2351|Homo sapiens coagulation factor VIII,
            procoagulant component (hemophilia A) protein.
          Length = 2351

 Score = 31.9 bits (69), Expect = 4.1
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 84   EGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGP 140
            + V+      L  G  A  P ++T D  +++  +  +K  + + N AT    H++GP
Sbjct: 981  KNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGP 1037


>AY769950-1|AAV85964.1| 2351|Homo sapiens coagulation factor VIII,
            procoagulant component (hemophilia A) protein.
          Length = 2351

 Score = 31.9 bits (69), Expect = 4.1
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 84   EGVAKVAKNLLAHGVTAFCPTMITSDQEIYRQILPRIKKTQGNKNGATVLGVHLEGP 140
            + V+      L  G  A  P ++T D  +++  +  +K  + + N AT    H++GP
Sbjct: 981  KNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGP 1037


>BC000059-1|AAH00059.2|  771|Homo sapiens CELSR1 protein protein.
          Length = 771

 Score = 30.7 bits (66), Expect = 9.4
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 73  VDFSRDSDNIE--EGVAKVAKNLLAHGVTAFCPTMIT--SDQEIYRQILPRIKKTQGNKN 128
           +  SRD DN    E + +V+ +   H VTAFC   +T  +D  +   I  R++     K 
Sbjct: 534 LQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITDDMLTNSITVRLENMSQEKF 593

Query: 129 GATVLGVHLEG--PFISPTKKGAHV 151
            + +L + +EG    +S TK    V
Sbjct: 594 LSPLLALFVEGVAAVLSTTKDDVFV 618


>AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
            G-type receptor 1 (flamingo homolog, Drosophila) protein.
          Length = 3014

 Score = 30.7 bits (66), Expect = 9.4
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 73   VDFSRDSDNIE--EGVAKVAKNLLAHGVTAFCPTMIT--SDQEIYRQILPRIKKTQGNKN 128
            +  SRD DN    E + +V+ +   H VTAFC   +T  +D  +   I  R++     K 
Sbjct: 1160 LQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITDDMLTNSITVRLENMSQEKF 1219

Query: 129  GATVLGVHLEG--PFISPTKKGAHV 151
             + +L + +EG    +S TK    V
Sbjct: 1220 LSPLLALFVEGVAAVLSTTKDDVFV 1244


>AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
            G-type receptor 1 (flamingo homolog, Drosophila) protein.
          Length = 3014

 Score = 30.7 bits (66), Expect = 9.4
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 73   VDFSRDSDNIE--EGVAKVAKNLLAHGVTAFCPTMIT--SDQEIYRQILPRIKKTQGNKN 128
            +  SRD DN    E + +V+ +   H VTAFC   +T  +D  +   I  R++     K 
Sbjct: 1160 LQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITDDMLTNSITVRLENMSQEKF 1219

Query: 129  GATVLGVHLEG--PFISPTKKGAHV 151
             + +L + +EG    +S TK    V
Sbjct: 1220 LSPLLALFVEGVAAVLSTTKDDVFV 1244


>AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven-pass
            G-type receptor 1 (flamingo homolog, Drosophila) protein.
          Length = 3014

 Score = 30.7 bits (66), Expect = 9.4
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 73   VDFSRDSDNIE--EGVAKVAKNLLAHGVTAFCPTMIT--SDQEIYRQILPRIKKTQGNKN 128
            +  SRD DN    E + +V+ +   H VTAFC   +T  +D  +   I  R++     K 
Sbjct: 1160 LQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITDDMLTNSITVRLENMSQEKF 1219

Query: 129  GATVLGVHLEG--PFISPTKKGAHV 151
             + +L + +EG    +S TK    V
Sbjct: 1220 LSPLLALFVEGVAAVLSTTKDDVFV 1244


>AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo 2
            protein.
          Length = 3014

 Score = 30.7 bits (66), Expect = 9.4
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 73   VDFSRDSDNIE--EGVAKVAKNLLAHGVTAFCPTMIT--SDQEIYRQILPRIKKTQGNKN 128
            +  SRD DN    E + +V+ +   H VTAFC   +T  +D  +   I  R++     K 
Sbjct: 1160 LQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITDDMLTNSITVRLENMSQEKF 1219

Query: 129  GATVLGVHLEG--PFISPTKKGAHV 151
             + +L + +EG    +S TK    V
Sbjct: 1220 LSPLLALFVEGVAAVLSTTKDDVFV 1244


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.319    0.138    0.415 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 59,452,789
Number of Sequences: 224733
Number of extensions: 2566439
Number of successful extensions: 4297
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 4269
Number of HSP's gapped (non-prelim): 23
length of query: 398
length of database: 73,234,838
effective HSP length: 92
effective length of query: 306
effective length of database: 52,559,402
effective search space: 16083177012
effective search space used: 16083177012
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 66 (30.7 bits)

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