BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001183-TA|BGIBMGA001183-PA|IPR003599|Immunoglobulin subtype, IPR003598|Immunoglobulin subtype 2, IPR001245|Tyrosine protein kinase, IPR002290|Serine/threonine protein kinase, IPR000719|Protein kinase, IPR008266|Tyrosine protein kinase, active site, IPR013838|Beta tubulin, autoregulation binding site, IPR001824|Receptor tyrosine kinase, class III, IPR007110|Immunoglobulin-like, IPR011009|Protein kinase-like, IPR013151|Immunoglobulin, IPR013098|Immunoglobulin I-set (1158 letters) Database: tribolium 317 sequences; 114,650 total letters Searching....................................................done Score E Sequences producing significant alignments: (bits) Value AY618898-1|AAU87291.1| 803|Tribolium castaneum receptor tyrosin... 169 1e-43 DQ157471-1|AAZ85125.1| 1639|Tribolium castaneum Down Syndrome ad... 42 2e-05 U09586-3|AAC47272.1| 470|Tribolium castaneum integrase protein. 25 3.0 >AY618898-1|AAU87291.1| 803|Tribolium castaneum receptor tyrosine kinase Torso-likeprotein protein. Length = 803 Score = 169 bits (410), Expect = 1e-43 Identities = 76/162 (46%), Positives = 109/162 (67%) Query: 801 HLLGWAFQIARGMEYLANRKVLHGDLAARNVLLADDNVVKICDFGLARSMYNNEEYQKKE 860 HLL A Q+A GME+LA +V+H DLAARNVL+ +++ VK+ DFGL+R +Y + Y K Sbjct: 593 HLLSIARQVALGMEHLAKTRVVHRDLAARNVLVCENHTVKVSDFGLSRDVYQDNVYCKNG 652 Query: 861 NSPLPVKWLAIECMVDRIFSTQSDVWSYGIVLWEMFSLAKTPYPNISPTDLLRWLSDGNR 920 LPV+W+A+E + + ++T SDVWS+G++LWE+ +L TPY + ++LL +L GNR Sbjct: 653 GGKLPVRWMALESLTHQRYTTYSDVWSFGVLLWEIVTLGGTPYVGVHSSELLDFLKSGNR 712 Query: 921 LEKPPFADDRLYNVMLRCWHQKPTARPSFTELQEILGNFLED 962 L +P LY VML CW + P RP+FTEL + L LE+ Sbjct: 713 LARPANCSPDLYAVMLNCWKECPKNRPTFTELSKSLEGLLEN 754 Score = 64.1 bits (149), Expect = 5e-12 Identities = 41/124 (33%), Positives = 70/124 (56%), Gaps = 5/124 (4%) Query: 585 PNLGIDEQADLLPYD--EKFEFPREKLTFGKQLGAGAFGVVYKAEARGIINAEVTTPVAV 642 P G + + +L+ D +++E KL+F +G GAFG+V +A + + T VAV Sbjct: 425 PESGENIEINLIKPDIFDQWELGPLKLSFQGVIGEGAFGIVRRAFLD--LKEDNKTQVAV 482 Query: 643 KMVKRTADNMYIKALASELKIMVHLGKHVNIVNLLGACTKHIAKRELIVIVEYCKYGNIH 702 KM+K + + I+ E+ IM + +H IV+L+G T+ A+ L+V VEYC G++ Sbjct: 483 KMLKESPTSEEIRQFTQEINIMKSVRQHPYIVSLIGCVTEGRAEGPLLV-VEYCSRGDLQ 541 Query: 703 NYMQ 706 Y++ Sbjct: 542 TYLR 545 >DQ157471-1|AAZ85125.1| 1639|Tribolium castaneum Down Syndrome adhesion molecule splicevariant 3.12.3.1 protein. Length = 1639 Score = 41.9 bits (94), Expect = 2e-05 Identities = 50/239 (20%), Positives = 89/239 (37%), Gaps = 25/239 (10%) Query: 91 PKVAGGHKQ-FLEGETFTIHCRVPNDGLINFKWKYPPEVTNDSVEVSVV-KTEATTTGSI 148 P V KQ + G T +HC + + W+ D ++ + K + G++ Sbjct: 512 PFVRSMEKQAIVAGGTLIVHCPFAGHPVDSVVWE------RDGRQLPINRKQKVFINGTL 565 Query: 149 VYQNITIRNATKKHNGVYTCLLTNTCG-EEKDEFRKIFLEKPFLSLRDLAKGKLMGNANK 207 + +N+ Y C+ N+ G + + P + D + + Sbjct: 566 IIENVE----RASDQATYDCVAKNSQGYSARGSLEVQVMVPPQILPFDFGEDSINEGDGV 621 Query: 208 SINIVIEIEAYP-PVERT---HFLKNDKYLPSNDLKYNVTTLANGDPKLRINDLKLTDIA 263 S+ + YP + T HF+ + N V+TL+ I++++ T + Sbjct: 622 SVQCTVSKGDYPLNISWTLNGHFIDQTNGIVINRASKRVSTLS-------IDNVQSTHVG 674 Query: 264 NYTLVAENKYLTKNYTVDLRVFTKPEAKLLNNRIIKRLENSEMNFACKVTGYPLPDVTW 322 NYT +A N YT L + P +L + S+ CK G+P P VTW Sbjct: 675 NYTCLASNSASVTTYTTSLFI-NVPPRWILEPTDKAFAQGSDAAVECKADGFPRPVVTW 732 Score = 39.5 bits (88), Expect = 1e-04 Identities = 74/373 (19%), Positives = 148/373 (39%), Gaps = 24/373 (6%) Query: 87 KPPKPKVAGGHKQFLEGETFTIHCRVPNDGLINFKWK-YPPEVTNDSVEVSVVKTEATTT 145 +PP+ + A + G + + C + W+ Y ++N E + + T Sbjct: 412 EPPQIRHAFNEETVQPGNSVFLKCIASGNPTPEITWELYGRRLSNS--ERNQIGQYVTVN 469 Query: 146 GSIVYQNITIRNATKKHNGVYTCLLTNTCGEEKDEFRKIFLEKPFLSLRDLAKGKLMGNA 205 G +V ++ I G+Y C+ ++ G R PF+ R + K ++ Sbjct: 470 GDVV-SHLNITAIHTNDGGLYRCVASSKVGSADHSARINVYGLPFV--RSMEKQAIVAGG 526 Query: 206 NKSINIVIEIEAYPPVERTHFLKNDKYLPSNDLKYNVTTLANGDPKLRINDLKLTDIANY 265 ++ A PV+ + ++ + LP N K V NG + N + +D A Y Sbjct: 527 TLIVHCPF---AGHPVDSVVWERDGRQLPINR-KQKV--FINGTLIIE-NVERASDQATY 579 Query: 266 TLVAENKY-LTKNYTVDLRVFTKPEAKLLNNRIIKRLENSEMNFACKVT--GYPLPDVTW 322 VA+N + +++++V P+ + E ++ C V+ YPL +++W Sbjct: 580 DCVAKNSQGYSARGSLEVQVMVPPQILPFDFGEDSINEGDGVSVQCTVSKGDYPL-NISW 638 Query: 323 IFSNDEEHELSSTKSEQESLYAKTDYLKISVQAS--GVITCNAHNSKGEYFDSSTLLVYE 380 + + + + S T + +VQ++ G TC A NS +++L + Sbjct: 639 TLNGHFIDQTNGIVINRASKRVSTLSID-NVQSTHVGNYTCLASNSASVTTYTTSLFINV 697 Query: 381 INNGFGILQPLENWYSEKDSARKKCLASVYDYDNVSWLGSDGNILDDIELLAPIIREPDS 440 IL+P + +++ A +C A + V+W + G D + P PD Sbjct: 698 PPRW--ILEPTDKAFAQGSDAAVECKADGFPRPVVTWKRATGVSPGDYKDFKP--NNPDI 753 Query: 441 NKDEEAMEGRSIQ 453 ++ + +IQ Sbjct: 754 KVEDGTLTINNIQ 766 Score = 39.5 bits (88), Expect = 1e-04 Identities = 22/72 (30%), Positives = 32/72 (44%) Query: 443 DEEAMEGRSIQLHCEAEGVPRPTIYWYKDDELISNNSGYKLFVDIVNHTIVNSTFEIENM 502 +E G S+ L C A G P P I W +SN+ ++ + + V S I + Sbjct: 422 EETVQPGNSVFLKCIASGNPTPEITWELYGRRLSNSERNQIGQYVTVNGDVVSHLNITAI 481 Query: 503 QEKDNGIYECVA 514 D G+Y CVA Sbjct: 482 HTNDGGLYRCVA 493 Score = 38.7 bits (86), Expect = 2e-04 Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Query: 443 DEEAMEGRSIQLHCEAEGVPRPTIYWYKDDELISNNSGYKLF-VDIVNHTIVNSTFEIEN 501 D+ +G + C+A+G PRP + W + + + YK F + + + + T I N Sbjct: 707 DKAFAQGSDAAVECKADGFPRPVVTWKRATGV--SPGDYKDFKPNNPDIKVEDGTLTINN 764 Query: 502 MQEKDNGIYECVALN 516 +Q+ + G Y C A+N Sbjct: 765 IQKTNEGYYLCEAVN 779 Score = 37.9 bits (84), Expect = 4e-04 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 9/79 (11%) Query: 440 SNKDEEAMEGRSIQLHCEAEGVPRPTIYWYKDDELISNNSGYKLFVDIVNHTIVNSTFEI 499 S + + + G ++ +HC G P ++ W +D + N K+F +N T I Sbjct: 516 SMEKQAIVAGGTLIVHCPFAGHPVDSVVWERDGRQLPINRKQKVF--------INGTLII 567 Query: 500 ENMQE-KDNGIYECVALNN 517 EN++ D Y+CVA N+ Sbjct: 568 ENVERASDQATYDCVAKNS 586 Score = 35.5 bits (78), Expect = 0.002 Identities = 45/212 (21%), Positives = 76/212 (35%), Gaps = 10/212 (4%) Query: 82 SKHIKKPPKPKVAGGHKQFLEGETFTIHCRVPNDGLINFKWKYPPEVT-NDSVEVSVVKT 140 S I PP+ + K F +G + C+ WK V+ D + Sbjct: 692 SLFINVPPRWILEPTDKAFAQGSDAAVECKADGFPRPVVTWKRATGVSPGDYKDFKPNNP 751 Query: 141 EATTTGSIVYQNITIRNATKKHNGVYTCLLTNTCGEEKDEFRKIFLEKPFLSLRDLAKGK 200 + +TI N K + G Y C N G +I ++ P D+ Sbjct: 752 DIKVEDG----TLTINNIQKTNEGYYLCEAVNGIGSGLSAVIQISVQAP--PQFDIKLRN 805 Query: 201 LMGNANKSINIVIEIEAYPPVERTHFLKNDKYLPSNDLKYNV--TTLANGD-PKLRINDL 257 + E + P+ + N + P D +Y + LANG L I Sbjct: 806 QTSRRGDPAVLQCEAKGEKPIGILWNINNKRLEPKGDNRYTIREEILANGVLSGLSIKRT 865 Query: 258 KLTDIANYTLVAENKYLTKNYTVDLRVFTKPE 289 + +D A +T VA N + + + ++++ V PE Sbjct: 866 ERSDSALFTCVATNAFGSDDTSINMIVQEVPE 897 Score = 34.3 bits (75), Expect = 0.005 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 6/89 (6%) Query: 435 IREPDSNKDEEAMEGRSIQLHCEAEGVPRPTIYWYKDD-ELISNNSGYKLFVDIVNHTIV 493 +REP + D G ++ C A G P P I W + D + + G + + N +V Sbjct: 26 VREPPNRIDFSNTTGAVVE--CSAHGNPTPDIIWVRSDGTAVGDVPGLRQV--LANGNLV 81 Query: 494 NSTFEIEN-MQEKDNGIYECVALNNASEL 521 F E+ QE +Y C+A N+ + Sbjct: 82 FPPFRAEDYRQEVHAQVYVCLAKNSVGSV 110 Score = 34.3 bits (75), Expect = 0.005 Identities = 30/136 (22%), Positives = 53/136 (38%), Gaps = 9/136 (6%) Query: 252 LRINDLKLTDIANYTLVAENKYLTKNYTVDLRV---FTKPEAKLLNNRIIKRLENSEMNF 308 LRI ++ D Y N + T +L++ F P+ + N + NS Sbjct: 375 LRIESVRKEDKGMYQCFIRNDQESAEATAELKLGGRFEPPQIRHAFNEETVQPGNSVF-L 433 Query: 309 ACKVTGYPLPDVTW-----IFSNDEEHELSSTKSEQESLYAKTDYLKISVQASGVITCNA 363 C +G P P++TW SN E +++ + + + + I G+ C A Sbjct: 434 KCIASGNPTPEITWELYGRRLSNSERNQIGQYVTVNGDVVSHLNITAIHTNDGGLYRCVA 493 Query: 364 HNSKGEYFDSSTLLVY 379 + G S+ + VY Sbjct: 494 SSKVGSADHSARINVY 509 Score = 33.9 bits (74), Expect = 0.006 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 450 RSIQLHCEAEGVPRPTIYWYKDDELISNNSGYKLFVDIVNHTIVNSTFEIENMQEKDNGI 509 +++ L C A+G P P+ WYK E + L D V V T I + +D+G Sbjct: 248 QNVALLCPAQGFPSPSFRWYKFVEGTTRKQAVTL-NDRVKQ--VAGTLIIREAKVEDSGK 304 Query: 510 YECVALNN 517 Y CV N+ Sbjct: 305 YLCVVNNS 312 Score = 33.5 bits (73), Expect = 0.009 Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 12/130 (9%) Query: 391 LENWYSEKDSARKKCLASVYDYDNVSWLGSDGNILDDIELLAPIIREPDSNKDEEAMEGR 450 +EN D A C+A N + G++ +++++ P P ++ EG Sbjct: 567 IENVERASDQATYDCVAK-----NSQGYSARGSL--EVQVMVPPQILPFDFGEDSINEGD 619 Query: 451 SIQLHCEAEGVPRP-TIYWYKDDELISNNSGYKLFVDIVNHTIVNSTFEIENMQEKDNGI 509 + + C P I W + I +G + ++ + + ST I+N+Q G Sbjct: 620 GVSVQCTVSKGDYPLNISWTLNGHFIDQTNG--IVINRASKRV--STLSIDNVQSTHVGN 675 Query: 510 YECVALNNAS 519 Y C+A N+AS Sbjct: 676 YTCLASNSAS 685 Score = 33.5 bits (73), Expect = 0.009 Identities = 25/129 (19%), Positives = 51/129 (39%), Gaps = 6/129 (4%) Query: 63 FVLCEFVRG-ETRIEKYIYVSKHIKKPPKPKVAGGHKQFLEGETFTIHCRVPNDGLINFK 121 + LCE V G + + I +S ++ PP+ + ++ G+ + C + I Sbjct: 772 YYLCEAVNGIGSGLSAVIQIS--VQAPPQFDIKLRNQTSRRGDPAVLQCEAKGEKPIGIL 829 Query: 122 WKYPPEVTNDSVEVS-VVKTEATTTGSIVYQNITIRNATKKHNGVYTCLLTNTCGEEKDE 180 W + + ++ E G V ++I+ + + ++TC+ TN G + Sbjct: 830 WNINNKRLEPKGDNRYTIREEILANG--VLSGLSIKRTERSDSALFTCVATNAFGSDDTS 887 Query: 181 FRKIFLEKP 189 I E P Sbjct: 888 INMIVQEVP 896 Score = 31.9 bits (69), Expect = 0.026 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 15/69 (21%) Query: 449 GRSIQLHCEAEGVPRPTIYWYKDDELISNNSGYKLFVDIVNHTIVNSTFEIENMQEKDNG 508 GR C EG P TI W KD I +N + IE+++++D G Sbjct: 342 GRPATFTCNFEGNPIKTISWLKDGHPIDHNE---------------AVLRIESVRKEDKG 386 Query: 509 IYECVALNN 517 +Y+C N+ Sbjct: 387 MYQCFIRND 395 Score = 27.9 bits (59), Expect = 0.42 Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 11/124 (8%) Query: 310 CKVTGYPLPDVTWIFSN----DEEHELSSTKSEQESLYA--KTDYLKISVQASGVITCNA 363 C G P PD+ W+ S+ + L + ++ + + + V A V C A Sbjct: 45 CSAHGNPTPDIIWVRSDGTAVGDVPGLRQVLANGNLVFPPFRAEDYRQEVHAQ-VYVCLA 103 Query: 364 HNSKGEYFDSSTLLVYEINNGFGILQPLENWYSEKDSARKKC--LASVYDYDNV-SWLGS 420 NS G S + V + N + + + + ++A KC + V D+ V +W+GS Sbjct: 104 KNSVGS-VHSRDVNVRAVVNQYYEAEVVSEYVIRGNTAVLKCNIPSFVADFVRVEAWVGS 162 Query: 421 DGNI 424 DG++ Sbjct: 163 DGSL 166 Score = 24.6 bits (51), Expect = 4.0 Identities = 21/99 (21%), Positives = 39/99 (39%), Gaps = 9/99 (9%) Query: 252 LRINDLKLTDIANYTLVAENKYLTKNYTVDLRVFTKPEAKLLNNRIIKRLE-NSEMNFAC 310 L I + K+ D Y V N ++ L V +AK+ ++ ++ F C Sbjct: 292 LIIREAKVEDSGKYLCVVNNSVGGESVETVLTVTAPLKAKIEPQ--VQTIDFGRPATFTC 349 Query: 311 KVTGYPLPDVTW------IFSNDEEHELSSTKSEQESLY 343 G P+ ++W I N+ + S + E + +Y Sbjct: 350 NFEGNPIKTISWLKDGHPIDHNEAVLRIESVRKEDKGMY 388 >U09586-3|AAC47272.1| 470|Tribolium castaneum integrase protein. Length = 470 Score = 25.0 bits (52), Expect = 3.0 Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 2/57 (3%) Query: 402 RKKCLASVYDYDNVSWLGSDGNILDDIELLAPIIREPDSNKDEEAME--GRSIQLHC 456 + KC+ S + +S + DI+ IR P+SN E M GR + +C Sbjct: 256 KPKCVLSDHGTQFISNTWQNSLRAADIQPTLSSIRHPESNPSERVMRELGRIFRAYC 312 Database: tribolium Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 114,650 Number of sequences in database: 317 Lambda K H 0.316 0.133 0.396 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 297,919 Number of Sequences: 317 Number of extensions: 14366 Number of successful extensions: 50 Number of sequences better than 10.0: 3 Number of HSP's better than 10.0 without gapping: 2 Number of HSP's successfully gapped in prelim test: 1 Number of HSP's that attempted gapping in prelim test: 24 Number of HSP's gapped (non-prelim): 22 length of query: 1158 length of database: 114,650 effective HSP length: 64 effective length of query: 1094 effective length of database: 94,362 effective search space: 103232028 effective search space used: 103232028 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 48 (23.4 bits)
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