BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001165-TA|BGIBMGA001165-PA|IPR001401|Dynamin, IPR000375|Dynamin central region, IPR003130|Dynamin GTPase effector (612 letters) Database: nematostella 59,808 sequences; 16,821,457 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SB_46217| Best HMM Match : No HMM Matches (HMM E-Value=.) 278 8e-75 SB_21750| Best HMM Match : Dynamin_M (HMM E-Value=0) 276 3e-74 SB_20156| Best HMM Match : GED (HMM E-Value=6.8e-16) 44 3e-04 SB_28483| Best HMM Match : Filament (HMM E-Value=0.0082) 36 0.13 SB_8391| Best HMM Match : Dynamin_N (HMM E-Value=9.7e-18) 35 0.22 SB_2557| Best HMM Match : No HMM Matches (HMM E-Value=.) 33 0.67 SB_2495| Best HMM Match : Pox_A_type_inc (HMM E-Value=8.2e-11) 33 0.89 SB_56681| Best HMM Match : adh_short (HMM E-Value=0.035) 32 1.6 SB_23766| Best HMM Match : 4_1_CTD (HMM E-Value=1.1) 32 1.6 SB_14169| Best HMM Match : YTH (HMM E-Value=0.00023) 32 1.6 SB_42510| Best HMM Match : MMR_HSR1 (HMM E-Value=5.3e-05) 31 2.7 SB_46477| Best HMM Match : No HMM Matches (HMM E-Value=.) 30 4.7 SB_43238| Best HMM Match : No HMM Matches (HMM E-Value=.) 30 4.7 SB_53505| Best HMM Match : No HMM Matches (HMM E-Value=.) 30 6.3 >SB_46217| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 882 Score = 278 bits (682), Expect = 8e-75 Identities = 137/191 (71%), Positives = 161/191 (84%), Gaps = 7/191 (3%) Query: 89 EWGKFLHTKDKIYTNFEEIRQEIERETDRMAGSNKGISPEPINLKIYSTTVVNLTLVDLP 148 EWGKFLH K+KI+ +F IR+EIERETDR+ GSNKGIS EPINLKIYS V+NLTLVDLP Sbjct: 140 EWGKFLHLKEKIFRDFNGIREEIERETDRVTGSNKGISSEPINLKIYSPKVLNLTLVDLP 199 Query: 149 G-------DQPEDIENQIRNLIIKYISNPNSIILAVTAANTDMATSEAIKLAKDVDPDGR 201 G DQP DIE QIR+LI++YISNPNSIILAVT AN D+ATSEA+K+A++VDPDG Sbjct: 200 GVTKVPVGDQPLDIEQQIRHLILQYISNPNSIILAVTPANIDLATSEALKIAREVDPDGH 259 Query: 202 RTLAVVTKLDLMDAGTDAIDILCGRVIPVKLGIIGVVNRSQQDIIDKKTITDALKDEATY 261 RTLAV TKLDLMD GTDA+D+L GRVIPVKLGIIGVVNRSQ DI ++K+I +AL+DEA + Sbjct: 260 RTLAVCTKLDLMDHGTDAMDVLYGRVIPVKLGIIGVVNRSQLDINNRKSIENALRDEAGF 319 Query: 262 LQRKYPTIATR 272 R YPT+A+R Sbjct: 320 FARNYPTVASR 330 Score = 191 bits (466), Expect = 1e-48 Identities = 95/132 (71%), Positives = 109/132 (82%), Gaps = 1/132 (0%) Query: 273 LTRMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEDPSLRCVELVHEEMQRIVQHC 332 L+ DILTAIRNATGPRPALFVPE+SFELLVKRQIRRLE+PSLRC+ELVHEEMQRI+QH Sbjct: 438 LSTRDILTAIRNATGPRPALFVPEISFELLVKRQIRRLEEPSLRCIELVHEEMQRIIQHS 497 Query: 333 GTEVQQEMLRFPRLHQRIVDVVTQLLRTRLPPTNSMVENLVAIELAYINTKHPDFHREAA 392 +V E+ RFPRLH+ IVDV+ LL+ RL P N MVENLVAIELAYINT HPDF A+ Sbjct: 498 FDQV-MEIKRFPRLHESIVDVIINLLQRRLMPCNEMVENLVAIELAYINTNHPDFTDGAS 556 Query: 393 LVSGLLKSGDDD 404 LVS L+ + + D Sbjct: 557 LVSSLVANQELD 568 Score = 138 bits (333), Expect = 2e-32 Identities = 64/92 (69%), Positives = 82/92 (89%) Query: 521 DLVERLIKSYFYIVRKSIQDSVPKAVMHFLVNFVKDNLQSELVTHLYKSDQAESMLNESE 580 D++ +LIKSYF IVRKSIQDSVPKA+M FLVN+VK+ +QSELV LYKS++ E++L ESE Sbjct: 791 DIIRKLIKSYFVIVRKSIQDSVPKAIMAFLVNYVKERIQSELVEKLYKSERFETLLQESE 850 Query: 581 HIAQRRKEAADMLKALQRAGQIISEIRETHMW 612 H+ +RKEAA+MLKALQRAGQIISE+R+TH++ Sbjct: 851 HMHIKRKEAAEMLKALQRAGQIISEVRDTHIY 882 Score = 69.7 bits (163), Expect = 6e-12 Identities = 47/102 (46%), Positives = 57/102 (55%), Gaps = 23/102 (22%) Query: 1 MEALIPVINKLQDVFNTVGADAIQLPQIAVLGTQ---------------------SSGKS 39 ME LIPVINKLQDVFNTVG+++IQLPQI V+G Q + Sbjct: 1 MEQLIPVINKLQDVFNTVGSESIQLPQIVVVGAQFIYFRLYAFLSMMQMAENENIARHTG 60 Query: 40 SVIESLVGRSFLPRGPGIVTRRPLILQLVYSPQEGKEHRSAE 81 ++ S FL G G+VTRRPLILQLV+ P KE + E Sbjct: 61 TLTNSHTKEMFL--GSGVVTRRPLILQLVHVPPRAKEKKINE 100 >SB_21750| Best HMM Match : Dynamin_M (HMM E-Value=0) Length = 498 Score = 276 bits (677), Expect = 3e-74 Identities = 145/269 (53%), Positives = 196/269 (72%), Gaps = 24/269 (8%) Query: 1 MEALIPVINKLQDVFNTVG-ADAIQLPQIAVLGTQSSGKSSVIESLVGRSFLPRGPGIVT 59 ME LIP++NK+QD F ++G + I LPQIAV+G+QS+GKSSV+E+ VG+ FLPRG GIVT Sbjct: 6 MEDLIPIVNKIQDAFASIGYSSMIDLPQIAVVGSQSAGKSSVLENFVGKDFLPRGSGIVT 65 Query: 60 RRPLILQLVYSPQEGKEHRSAEEGTLNLEEWGKFLHTKDKIYTNFEEIRQEIERETDRMA 119 RRPLILQL Q K E+ +FLH ++K +T+F E+++EI ETDR+ Sbjct: 66 RRPLILQL----QPSKS------------EYAEFLHCRNKKFTDFGEVQKEIVAETDRVT 109 Query: 120 GSNKGISPEPINLKIYSTTVVNLTLVDLPG-------DQPEDIENQIRNLIIKYISNPNS 172 G NKGIS PINL++YS +V++LTLVDLPG DQP DIE QIR++++++I+ N Sbjct: 110 GGNKGISNIPINLRVYSPSVLSLTLVDLPGMTKVPVGDQPADIEFQIRSMLLEFITKENC 169 Query: 173 IILAVTAANTDMATSEAIKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKL 232 +ILAV+ AN+D+A S+A+K+A++VDP G RT+ V+TKLDLMD GTDA DIL RV+P++ Sbjct: 170 LILAVSPANSDLANSDALKIAREVDPQGARTIGVITKLDLMDEGTDARDILENRVLPLRR 229 Query: 233 GIIGVVNRSQQDIIDKKTITDALKDEATY 261 G IG+VNRSQ DI +K I AL E + Sbjct: 230 GYIGIVNRSQADIDGRKDIRAALAAERKF 258 Score = 97.9 bits (233), Expect = 2e-20 Identities = 44/113 (38%), Positives = 71/113 (62%), Gaps = 4/113 (3%) Query: 275 RMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEDPSLRCVELVHEEMQRIVQHCGT 334 R +I+ AI+N G R LF P+++FE +VKRQI +L P+++CV++V E+ ++Q C T Sbjct: 385 RREIMFAIKNIHGIRVGLFTPDMAFEAIVKRQIDKLRSPAIKCVDMVMTELTSVIQKCAT 444 Query: 335 EVQQEMLRFPRLHQRIVDVVTQLLRTRLPPTNSMVENLVAIELAYINTKHPDF 387 +M ++P L ++ +V +R+ T V+ + +ELAYINT HPDF Sbjct: 445 ----QMAKYPLLRDQVERIVIDHIRSNEVTTKEQVQTFIELELAYINTNHPDF 493 >SB_20156| Best HMM Match : GED (HMM E-Value=6.8e-16) Length = 172 Score = 44.4 bits (100), Expect = 3e-04 Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 20/96 (20%) Query: 515 QLNQMGDLVERLIKSYFYIVRKSIQDSVPKAVMHFLVNFVKDNLQSELVTHLYKSDQAES 574 Q+ + + + L+ SY IV K+I+D VPK +M+ ++N SD Sbjct: 54 QMERQVETIRNLVDSYIRIVSKTIRDLVPKTIMYMIIN---------------NSD---- 94 Query: 575 MLNESEHIAQRRKEAADMLKALQRAGQIISEIRETH 610 ++ ESE AQRR+E M + + A QI+ +I +TH Sbjct: 95 LMEESEEEAQRREEMLKMYHSTKEALQIVGDI-DTH 129 >SB_28483| Best HMM Match : Filament (HMM E-Value=0.0082) Length = 478 Score = 35.5 bits (78), Expect = 0.13 Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 7/108 (6%) Query: 92 KFLHTKDKIYTNFEEIRQEIERETDRMAGSNKGISPEPINLKIYSTTV----VNLTLVDL 147 + + + K + EEI +E + E + + + + K+++ T +N+ L L Sbjct: 263 EIVELESKHSAHVEEILEEHQLEIETIKADYEE-QRSALETKLFAVTSECTSLNIKLQRL 321 Query: 148 PGDQPEDIENQIRNLIIKYISNPNSIILAVTAANTDMATSEAIKLAKD 195 + +DIEN+I++ I KY S P+ LA A DM E +L KD Sbjct: 322 QEETEQDIENRIQDAIEKYKSLPDE--LASMKAVLDMKNDEIKQLRKD 367 >SB_8391| Best HMM Match : Dynamin_N (HMM E-Value=9.7e-18) Length = 957 Score = 34.7 bits (76), Expect = 0.22 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Query: 28 IAVLGTQSSGKSSVIESLVGRSFLPRGPGIVTRRPLILQLVYSPQEGKEHRSAE-EGTLN 86 I V+G +SGKSS+I L+G ++LP T R I+++ YS E + E Sbjct: 95 ILVVGQTNSGKSSLINELLGGTYLPTAEIPCTSR--IVRICYSDNNYVEVQGPNGECVQG 152 Query: 87 LEEWGKFLHTKDKIYTNFEEIRQEIE 112 + +GK +D+I + ++ R + E Sbjct: 153 KQSFGKKRIPRDEIALDDDKKRSDAE 178 >SB_2557| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 627 Score = 33.1 bits (72), Expect = 0.67 Identities = 15/64 (23%), Positives = 32/64 (50%) Query: 151 QPEDIENQIRNLIIKYISNPNSIILAVTAANTDMATSEAIKLAKDVDPDGRRTLAVVTKL 210 Q + + ++ ++ +K +++ + D S L +DP G+RT+ V+TK+ Sbjct: 128 QGQTVSPEVISMTVKGPGLHRMVLVDLPDGAIDAERSNVTDLVSSMDPQGKRTIFVLTKV 187 Query: 211 DLMD 214 DL + Sbjct: 188 DLAE 191 Score = 31.5 bits (68), Expect = 2.1 Identities = 14/59 (23%), Positives = 30/59 (50%) Query: 105 EEIRQEIERETDRMAGSNKGISPEPINLKIYSTTVVNLTLVDLPGDQPEDIENQIRNLI 163 +++R E+E R + +SPE I++ + + + LVDLP + + + +L+ Sbjct: 112 KDLRHEVELRMKRSVKQGQTVSPEVISMTVKGPGLHRMVLVDLPDGAIDAERSNVTDLV 170 >SB_2495| Best HMM Match : Pox_A_type_inc (HMM E-Value=8.2e-11) Length = 2024 Score = 32.7 bits (71), Expect = 0.89 Identities = 46/196 (23%), Positives = 81/196 (41%), Gaps = 16/196 (8%) Query: 185 ATSEAIKLAKDVDPDGRRTLAVVTKL-DLMDAGT---DAIDILCGRVIPVKLGIIGVVNR 240 ATS+ L + + R ++ T+L DL GT + + L + KL I VNR Sbjct: 3 ATSQVCDLEVKYEYECREKASLETQLEDLKKRGTTNREELSKLEQTITEQKLAI-DTVNR 61 Query: 241 SQQDIIDKKTITDALKDEATYLQRKYPTIATRLTRMDILTAIRNATGPRPALFVPEVSFE 300 D+ DK+ + LKD +L+ + T+ L R+ R + + E Sbjct: 62 ---DVKDKEHYIEQLKDGKEFLEEQLKTLRLSLEE-------RDKESERSRQELSGIQRE 111 Query: 301 LLVKRQIRRLEDPSLRCVELVHEEMQRIVQHCGTEVQQEMLRFPRLHQRIVDVVTQLLRT 360 LL + D ++ L + +QRI + T V +E + H+ + + ++QL T Sbjct: 112 LLSLKSSTSDHDARIKKSNLERDRIQRI-EGDYTAVMEEKKKVEAQHKAMTEKISQLSST 170 Query: 361 RLPPTNSMVENLVAIE 376 + E V ++ Sbjct: 171 SETEMKKIREENVVVK 186 >SB_56681| Best HMM Match : adh_short (HMM E-Value=0.035) Length = 437 Score = 31.9 bits (69), Expect = 1.6 Identities = 33/145 (22%), Positives = 66/145 (45%), Gaps = 15/145 (10%) Query: 186 TSEAIKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKL---GIIGVVNRSQ 242 +SE++ L K +D RR+ A KL++ +G D C V+L ++ + N + Sbjct: 288 SSESVLLEKRLDDLCRRSSAQKKKLNVRGSGKPRFDF-CNSACKVRLLRKEVVEIKNLVE 346 Query: 243 QDIIDKKTITD------ALKDEATYLQRKYPTIATRLTRMDILTAIRNATGPRPALFVPE 296 + + + +I + ALKDE L+ ++ ++ + T N P +PE Sbjct: 347 ERVEETSSIAERDELVKALKDEVRRLKGNNDSLRQQIRHLKRETCDANVGTP-----IPE 401 Query: 297 VSFELLVKRQIRRLEDPSLRCVELV 321 + E R+I+ L++ + + + V Sbjct: 402 LKTEQSKNRKIKILKNKAEKALAFV 426 >SB_23766| Best HMM Match : 4_1_CTD (HMM E-Value=1.1) Length = 69 Score = 31.9 bits (69), Expect = 1.6 Identities = 14/38 (36%), Positives = 25/38 (65%) Query: 174 ILAVTAANTDMATSEAIKLAKDVDPDGRRTLAVVTKLD 211 ++A +TD A +EAI+ A++ DP+ + T V+T+ D Sbjct: 28 VIATGDPDTDAAIAEAIRQAREADPNVKVTEVVITRND 65 >SB_14169| Best HMM Match : YTH (HMM E-Value=0.00023) Length = 906 Score = 31.9 bits (69), Expect = 1.6 Identities = 33/150 (22%), Positives = 59/150 (39%), Gaps = 6/150 (4%) Query: 17 TVGADAIQLPQIAVLGTQSSGKSSVIESLVGRSFLPRGPG----IVTRRPLILQLVYSPQ 72 T + I+ P SS +E + G FLP PG + R P+ Q ++ Sbjct: 745 TTSHEDIRAPAEGTAPKSSSAFGGSVEDIAGEDFLPVDPGCYYSVALRCPINSQRIFWAS 804 Query: 73 EGKEHRSAEEGTLNLEEWGKFLHTKDKIYTNFEEIRQ-EIERETDRMAGSNKGISPE-PI 130 + ++ EE L ++ K + TN ++ + +T +G+ E P Sbjct: 805 LKRTNQQNEEYNQFLSNLKSYMEAKGESLTNPFLLKSCCVRSDTKGRVRYRRGLIVEIPS 864 Query: 131 NLKIYSTTVVNLTLVDLPGDQPEDIENQIR 160 N KI +L + + P + PE + Q + Sbjct: 865 NDKIGQGLEGDLAVGNRPREIPEHCKPQYK 894 >SB_42510| Best HMM Match : MMR_HSR1 (HMM E-Value=5.3e-05) Length = 202 Score = 31.1 bits (67), Expect = 2.7 Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Query: 17 TVGADAIQLPQIAVLGTQSSGKSSVIESLVGRSFLPRGPGIVTRRPLILQLVYS 70 ++ D + +P + V+G Q+ GKS+ + L+ +LP T R I+++ YS Sbjct: 55 SLSKDGLFIPSVIVIGNQNCGKSTFLNVLLKGKYLPVHENPCTSR--IVRISYS 106 >SB_46477| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 6116 Score = 30.3 bits (65), Expect = 4.7 Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Query: 133 KIYSTTVVNLTLVDLPGDQPEDIENQIRNLIIKYISNPNSIILAVTAANTD 183 ++++TT V++T++DL D P + + N I S + + VTA++ D Sbjct: 5388 QLFNTTTVHITVLDL-NDNPPAFDKAVFNASIAENSESGASVTRVTASDRD 5437 >SB_43238| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 2532 Score = 30.3 bits (65), Expect = 4.7 Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 5/92 (5%) Query: 88 EEWGKFLHTKDKIYTNFEEIRQEIERETD--RMAG-SNKGISPEPINLKIYSTTVVNLTL 144 EE K T +KI + ++I++ I+ ++ +A SN + + + TV N Sbjct: 228 EEVSKLKVTTEKIAGDIQDIKRSIQGQSSSGHVANISNVTLKDGATSAVADNATVSNTVS 287 Query: 145 --VDLPGDQPEDIENQIRNLIIKYISNPNSII 174 V+ P +P+ IEN I+ L KY + N++I Sbjct: 288 ASVEKPHTRPKVIENLIKCLREKYTTGENALI 319 >SB_53505| Best HMM Match : No HMM Matches (HMM E-Value=.) Length = 342 Score = 29.9 bits (64), Expect = 6.3 Identities = 14/36 (38%), Positives = 24/36 (66%), Gaps = 1/36 (2%) Query: 16 NTVGADAIQLPQIAVLGTQSSGKSSVIESLVGRSFL 51 +TV D +L ++A++G +SGKS++I LVG + Sbjct: 31 STVAPDT-KLLKVAIIGEPNSGKSTLINQLVGEKIV 65 Database: nematostella Posted date: Oct 22, 2007 1:22 PM Number of letters in database: 16,821,457 Number of sequences in database: 59,808 Lambda K H 0.318 0.134 0.376 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 19,217,130 Number of Sequences: 59808 Number of extensions: 797387 Number of successful extensions: 2338 Number of sequences better than 10.0: 14 Number of HSP's better than 10.0 without gapping: 7 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 2313 Number of HSP's gapped (non-prelim): 27 length of query: 612 length of database: 16,821,457 effective HSP length: 86 effective length of query: 526 effective length of database: 11,677,969 effective search space: 6142611694 effective search space used: 6142611694 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 63 (29.5 bits)
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