Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001163-TA|BGIBMGA001163-PA|IPR002290|Serine/threonine
protein kinase, IPR000961|Protein kinase, C-terminal,
IPR000719|Protein kinase, IPR008271|Serine/threonine protein kinase,
active site, IPR011009|Protein kinase-like
(366 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P17612 Cluster: cAMP-dependent protein kinase, alpha-ca... 457 e-127
UniRef50_Q17JG1 Cluster: Camp-dependent protein kinase catalytic... 418 e-115
UniRef50_P22612 Cluster: cAMP-dependent protein kinase, gamma-ca... 414 e-114
UniRef50_P34099 Cluster: cAMP-dependent protein kinase catalytic... 369 e-101
UniRef50_Q9VA47 Cluster: CG12069-PA; n=3; Sophophora|Rep: CG1206... 349 9e-95
UniRef50_Q4E4S9 Cluster: Protein kinase A catalytic subunit isof... 344 2e-93
UniRef50_UPI000155CDCE Cluster: PREDICTED: similar to protein ki... 344 3e-93
UniRef50_P51817 Cluster: Serine/threonine-protein kinase PRKX; n... 341 2e-92
UniRef50_Q8NIL1 Cluster: CAMP-dependent protein kinase catalytic... 332 6e-90
UniRef50_P40376 Cluster: cAMP-dependent protein kinase catalytic... 323 4e-87
UniRef50_Q9BMY6 Cluster: CAMP-dependent protein kinase catalytic... 317 3e-85
UniRef50_O13367 Cluster: CAMP-dependent protein kinase catalytic... 315 1e-84
UniRef50_Q22DD1 Cluster: Protein kinase domain containing protei... 311 2e-83
UniRef50_Q20541 Cluster: Cyclic AMP-dependent protein kinase, ca... 309 9e-83
UniRef50_P21901 Cluster: Spermatozoon-associated protein kinase;... 309 9e-83
UniRef50_Q6CW38 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 305 1e-81
UniRef50_P05986 Cluster: cAMP-dependent protein kinase type 3; n... 305 1e-81
UniRef50_A0CDF0 Cluster: Chromosome undetermined scaffold_17, wh... 301 2e-80
UniRef50_Q8J0I6 Cluster: CAMP-dependent protein kinase A catalyt... 300 4e-80
UniRef50_Q33DX4 Cluster: Putative cyclic AMP-dependent protein k... 297 4e-79
UniRef50_O44020 Cluster: PKA protein; n=13; Eukaryota|Rep: PKA p... 293 4e-78
UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1; Chl... 283 5e-75
UniRef50_Q33DX3 Cluster: Putative cyclic AMP-dependent protein k... 283 5e-75
UniRef50_Q2U6J7 Cluster: CAMP-dependent protein kinase catalytic... 283 7e-75
UniRef50_Q86ZN6 Cluster: CAMP-dependent protein kinase catalytic... 279 6e-74
UniRef50_A6QTK8 Cluster: Serine/threonine-protein kinase PRKX; n... 279 1e-73
UniRef50_P28178 Cluster: Protein kinase 2; n=2; Dictyostelium di... 278 1e-73
UniRef50_Q24HP6 Cluster: Protein kinase domain containing protei... 277 3e-73
UniRef50_Q17941 Cluster: Serine/threonine-protein kinase akt-1; ... 277 3e-73
UniRef50_Q4UE84 Cluster: CAMP-dependent protein kinase catalytic... 276 8e-73
UniRef50_P16911 Cluster: Protein kinase DC1; n=5; Sophophora|Rep... 275 1e-72
UniRef50_Q4XNV1 Cluster: Rac-beta serine/threonine protein kinas... 274 3e-72
UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta i... 273 4e-72
UniRef50_Q6PLK2 Cluster: Protein kinase B-like protein; n=4; Pla... 272 9e-72
UniRef50_A0BY36 Cluster: Chromosome undetermined scaffold_136, w... 271 2e-71
UniRef50_P31751 Cluster: RAC-beta serine/threonine-protein kinas... 270 4e-71
UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=... 269 7e-71
UniRef50_P54644 Cluster: RAC family serine/threonine-protein kin... 269 7e-71
UniRef50_Q2U061 Cluster: Ribosomal protein S6 kinase and related... 268 2e-70
UniRef50_Q9P7J8 Cluster: Serine/threonine-protein kinase gad8; n... 268 2e-70
UniRef50_A5DTG0 Cluster: Serine/threonine-protein kinase YPK1; n... 267 3e-70
UniRef50_P12688 Cluster: Serine/threonine-protein kinase YPK1; n... 267 3e-70
UniRef50_Q2PJ68 Cluster: Putative uncharacterized protein sgk-1;... 265 1e-69
UniRef50_A0E058 Cluster: Chromosome undetermined scaffold_71, wh... 264 3e-69
UniRef50_A5K8X1 Cluster: Rac-beta serine/threonine protein kinas... 264 3e-69
UniRef50_Q6CD34 Cluster: Yarrowia lipolytica chromosome C of str... 263 6e-69
UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome s... 262 8e-69
UniRef50_Q5K7C2 Cluster: Protein kinase Sch9, putative; n=4; Aga... 262 8e-69
UniRef50_Q96BR1 Cluster: Serine/threonine-protein kinase Sgk3; n... 262 1e-68
UniRef50_Q231C9 Cluster: Protein kinase C terminal domain contai... 261 2e-68
UniRef50_Q4DL90 Cluster: Rac serine-threonine kinase, putative; ... 260 5e-68
UniRef50_A0CMB4 Cluster: Chromosome undetermined scaffold_21, wh... 259 9e-68
UniRef50_Q240P0 Cluster: Protein kinase domain containing protei... 257 4e-67
UniRef50_Q26334 Cluster: Serine/threonine protein kinase; n=2; E... 256 5e-67
UniRef50_P11792 Cluster: Serine/threonine-protein kinase SCH9; n... 256 7e-67
UniRef50_Q8INB9 Cluster: RAC serine/threonine-protein kinase; n=... 256 7e-67
UniRef50_Q2UNA7 Cluster: Ribosomal protein S6 kinase and related... 255 2e-66
UniRef50_Q9HGS0 Cluster: CAMP-dependent protein kinase catalytic... 254 2e-66
UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23; ... 254 3e-66
UniRef50_Q7R5X8 Cluster: GLP_81_97826_96747; n=2; Giardia intest... 254 4e-66
UniRef50_UPI000049878B Cluster: protein kinase; n=3; Entamoeba h... 253 6e-66
UniRef50_Q4PH11 Cluster: Putative uncharacterized protein; n=1; ... 252 8e-66
UniRef50_Q9UBS0 Cluster: Ribosomal protein S6 kinase beta-2; n=6... 252 1e-65
UniRef50_Q54IF2 Cluster: Putative uncharacterized protein; n=1; ... 252 1e-65
UniRef50_Q6C936 Cluster: Yarrowia lipolytica chromosome D of str... 252 1e-65
UniRef50_A5DV85 Cluster: Serine/threonine-protein kinase SCH9; n... 251 2e-65
UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme ... 251 2e-65
UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate pro... 251 2e-65
UniRef50_A7AWS2 Cluster: cAMP-dependent protein kinase; n=1; Bab... 251 2e-65
UniRef50_Q245J7 Cluster: Protein kinase domain containing protei... 250 4e-65
UniRef50_Q9NAH6 Cluster: Putative uncharacterized protein rsks-1... 249 8e-65
UniRef50_A1CR23 Cluster: CAMP-dependent protein kinase, putative... 249 8e-65
UniRef50_UPI00006CB772 Cluster: Protein kinase domain containing... 249 1e-64
UniRef50_A0E7B2 Cluster: Chromosome undetermined scaffold_80, wh... 249 1e-64
UniRef50_A0BEY5 Cluster: Chromosome undetermined scaffold_103, w... 249 1e-64
UniRef50_Q7QUE9 Cluster: GLP_59_15138_16382; n=2; Giardia intest... 247 3e-64
UniRef50_A0CFD9 Cluster: Chromosome undetermined scaffold_175, w... 247 4e-64
UniRef50_Q22RI5 Cluster: Protein kinase domain containing protei... 246 7e-64
UniRef50_P50530 Cluster: Serine/threonine-protein kinase sck1; n... 246 7e-64
UniRef50_Q8MYF1 Cluster: Similar to Dictyostelium discoideum (Sl... 245 1e-63
UniRef50_UPI000065EC1B Cluster: Homolog of Fugu rubripes "Protei... 244 3e-63
UniRef50_A2BIH5 Cluster: Novel protein similar to vertebrate pro... 244 3e-63
UniRef50_Q39030 Cluster: Serine/threonine-protein kinase AtPK19;... 244 3e-63
UniRef50_UPI00006CFFA7 Cluster: Protein kinase domain containing... 244 4e-63
UniRef50_UPI000049A5C0 Cluster: protein kinase; n=1; Entamoeba h... 244 4e-63
UniRef50_Q4SLK1 Cluster: Chromosome 15 SCAF14556, whole genome s... 243 5e-63
UniRef50_Q10364 Cluster: Serine/threonine-protein kinase sck2; n... 243 5e-63
UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5; ... 242 1e-62
UniRef50_A0DUX2 Cluster: Chromosome undetermined scaffold_65, wh... 242 1e-62
UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome s... 241 2e-62
UniRef50_A7TPV4 Cluster: Putative uncharacterized protein; n=1; ... 241 2e-62
UniRef50_Q22HC2 Cluster: Protein kinase domain containing protei... 241 2e-62
UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform... 241 2e-62
UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to cGMP-depen... 241 3e-62
UniRef50_P23443 Cluster: Ribosomal protein S6 kinase beta-1 (EC ... 240 5e-62
UniRef50_Q39908 Cluster: CAMP-dependent protein kinase; n=1; Gon... 238 1e-61
UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2; End... 238 2e-61
UniRef50_O17874 Cluster: Putative uncharacterized protein; n=2; ... 238 2e-61
UniRef50_A2DS63 Cluster: AGC family protein kinase; n=3; Trichom... 238 2e-61
UniRef50_P34885 Cluster: Protein kinase C-like 1B; n=4; Bilateri... 237 2e-61
UniRef50_Q23YB5 Cluster: Protein kinase domain containing protei... 237 3e-61
UniRef50_Q04759 Cluster: Protein kinase C theta type; n=20; Eute... 236 8e-61
UniRef50_UPI000150A8F4 Cluster: Protein kinase domain containing... 235 1e-60
UniRef50_A0DLX8 Cluster: Chromosome undetermined scaffold_56, wh... 235 1e-60
UniRef50_Q584T1 Cluster: Rac serine-threonine kinase, putative; ... 235 1e-60
UniRef50_A0DTL3 Cluster: Chromosome undetermined scaffold_63, wh... 235 1e-60
UniRef50_P83099 Cluster: Putative protein kinase C delta type ho... 235 1e-60
UniRef50_UPI00015A51B8 Cluster: Protein kinase C delta type (EC ... 235 2e-60
UniRef50_UPI00015B57E6 Cluster: PREDICTED: similar to protein ki... 234 2e-60
UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14; Ap... 234 3e-60
UniRef50_Q24DD1 Cluster: Protein kinase domain containing protei... 233 5e-60
UniRef50_UPI0001509D2B Cluster: Protein kinase C terminal domain... 233 7e-60
UniRef50_Q1MX42 Cluster: Protein kinase C, delta V; n=9; Euteleo... 233 7e-60
UniRef50_Q21694 Cluster: Putative uncharacterized protein; n=2; ... 233 7e-60
UniRef50_Q12706 Cluster: Serine/threonine-protein kinase psk1; n... 233 7e-60
UniRef50_O61224 Cluster: Serine/Threonine protein kinase; n=1; S... 232 1e-59
UniRef50_Q9UK32 Cluster: Ribosomal protein S6 kinase alpha-6; n=... 232 1e-59
UniRef50_UPI0000499868 Cluster: protein kinase; n=1; Entamoeba h... 231 2e-59
UniRef50_A0E8L1 Cluster: Chromosome undetermined scaffold_83, wh... 231 2e-59
UniRef50_A1CKA9 Cluster: Serine/threonine protein kinase, putati... 231 2e-59
UniRef50_A2F9U6 Cluster: AGC family protein kinase; n=1; Trichom... 231 3e-59
UniRef50_P24723 Cluster: Protein kinase C eta type; n=44; Eumeta... 231 3e-59
UniRef50_Q4SYX7 Cluster: Chromosome 21 SCAF11909, whole genome s... 230 4e-59
UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2; Eim... 230 4e-59
UniRef50_A7SL27 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 230 4e-59
UniRef50_A2FLX7 Cluster: AGC family protein kinase; n=4; Trichom... 230 4e-59
UniRef50_Q16513 Cluster: Serine/threonine-protein kinase N2; n=4... 230 4e-59
UniRef50_Q05655 Cluster: Protein kinase C delta type; n=61; Eume... 230 4e-59
UniRef50_O96997 Cluster: Protein kinase C; n=2; Tetractinomorpha... 230 5e-59
UniRef50_P90980 Cluster: Protein kinase C-like 2; n=49; Eumetazo... 230 5e-59
UniRef50_UPI00006CC8B4 Cluster: Protein kinase domain containing... 229 1e-58
UniRef50_UPI00006CB393 Cluster: Protein kinase domain containing... 228 2e-58
UniRef50_UPI00006607B3 Cluster: RAC-beta serine/threonine-protei... 228 2e-58
UniRef50_A0CNT4 Cluster: Chromosome undetermined scaffold_22, wh... 228 2e-58
UniRef50_A6QRT1 Cluster: Serine/threonine-protein kinase psk1; n... 228 2e-58
UniRef50_Q4N4B2 Cluster: CAMP-dependent protein kinase catalytic... 227 3e-58
UniRef50_O42632 Cluster: Protein kinase C-like; n=14; Fungi|Rep:... 227 3e-58
UniRef50_A0BJU7 Cluster: Chromosome undetermined scaffold_110, w... 227 5e-58
UniRef50_Q00078 Cluster: Protein kinase C-like; n=8; Eurotiomyce... 226 8e-58
UniRef50_Q6C292 Cluster: Similar to sp|P24583 Saccharomyces cere... 225 1e-57
UniRef50_P13677 Cluster: Protein kinase C, eye isozyme (EC 2.7.1... 225 1e-57
UniRef50_Q16QY2 Cluster: Ribosomal protein S6 kinase, 90kD, poly... 225 1e-57
UniRef50_A1Z7T1 Cluster: CG2049-PC, isoform C; n=7; Fungi/Metazo... 225 1e-57
UniRef50_A0DVL2 Cluster: Chromosome undetermined scaffold_66, wh... 225 1e-57
UniRef50_Q6UB97 Cluster: Protein kinase C 1; n=7; Dikarya|Rep: P... 225 1e-57
UniRef50_A6RHI7 Cluster: Serine/threonine-protein kinase Sgk2; n... 225 1e-57
UniRef50_UPI00004999BB Cluster: protein kinase; n=3; Entamoeba h... 224 2e-57
UniRef50_A0DZB2 Cluster: Chromosome undetermined scaffold_7, who... 224 2e-57
UniRef50_Q7PRV3 Cluster: ENSANGP00000020017; n=1; Anopheles gamb... 224 3e-57
UniRef50_A2DL59 Cluster: AGC family protein kinase; n=1; Trichom... 223 4e-57
UniRef50_Q86ZV2 Cluster: Protein kinase C; n=1; Pichia pastoris|... 223 4e-57
UniRef50_O62570 Cluster: Protein kinase C-related kinase; n=1; S... 223 8e-57
UniRef50_A2DA20 Cluster: AGC family protein kinase; n=2; Trichom... 222 1e-56
UniRef50_Q16512 Cluster: Serine/threonine-protein kinase N1; n=2... 222 1e-56
UniRef50_Q62074 Cluster: Protein kinase C iota type; n=26; Eumet... 222 1e-56
UniRef50_P41743 Cluster: Protein kinase C iota type; n=97; Bilat... 222 1e-56
UniRef50_Q22A18 Cluster: Protein kinase domain containing protei... 222 1e-56
UniRef50_A0DPW4 Cluster: Chromosome undetermined scaffold_6, who... 221 2e-56
UniRef50_P87253 Cluster: Protein kinase C-like; n=6; Pezizomycot... 221 2e-56
UniRef50_Q0UME1 Cluster: Putative uncharacterized protein; n=1; ... 221 3e-56
UniRef50_Q4RZQ9 Cluster: Chromosome 18 SCAF14786, whole genome s... 220 4e-56
UniRef50_A2D9C1 Cluster: AGC family protein kinase; n=4; Trichom... 220 4e-56
UniRef50_Q9V3I5 Cluster: Chromosomal serine/threonine-protein ki... 220 4e-56
UniRef50_Q4RM42 Cluster: Chromosome 10 SCAF15019, whole genome s... 220 5e-56
UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, wh... 219 7e-56
UniRef50_P36583 Cluster: Protein kinase C-like 2; n=1; Schizosac... 219 7e-56
UniRef50_A0CC53 Cluster: Chromosome undetermined scaffold_166, w... 219 9e-56
UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent prot... 219 1e-55
UniRef50_A0C512 Cluster: Chromosome undetermined scaffold_15, wh... 219 1e-55
UniRef50_A0BNJ0 Cluster: Chromosome undetermined scaffold_118, w... 218 2e-55
UniRef50_O75582 Cluster: Ribosomal protein S6 kinase alpha-5; n=... 218 2e-55
UniRef50_Q02156 Cluster: Protein kinase C epsilon type; n=34; Co... 217 3e-55
UniRef50_Q4SG88 Cluster: Chromosome 17 SCAF14597, whole genome s... 217 5e-55
UniRef50_Q23PX4 Cluster: Protein kinase domain containing protei... 217 5e-55
UniRef50_UPI00006CDDB0 Cluster: Protein kinase domain containing... 216 7e-55
UniRef50_O61225 Cluster: Serine/Threonine protein kinase; n=1; S... 216 7e-55
UniRef50_P34722 Cluster: Protein kinase C-like 1; n=3; Caenorhab... 216 7e-55
UniRef50_A0D8K8 Cluster: Chromosome undetermined scaffold_41, wh... 216 9e-55
UniRef50_Q69G16 Cluster: Protein kinase C type beta; n=2; Bilate... 215 1e-54
UniRef50_O62569 Cluster: Serine/Threonine protein kinase; n=1; S... 215 1e-54
UniRef50_P05129 Cluster: Protein kinase C gamma type; n=98; Eume... 215 1e-54
UniRef50_Q91948 Cluster: PKN; n=3; Euteleostomi|Rep: PKN - Xenop... 215 2e-54
UniRef50_A2F0I9 Cluster: AGC family protein kinase; n=1; Trichom... 215 2e-54
UniRef50_A0E8C9 Cluster: Chromosome undetermined scaffold_82, wh... 215 2e-54
UniRef50_Q6CBU3 Cluster: Yarrowia lipolytica chromosome C of str... 215 2e-54
UniRef50_Q8C050 Cluster: Ribosomal protein S6 kinase alpha-5; n=... 215 2e-54
UniRef50_A2FMG9 Cluster: AGC family protein kinase; n=2; Trichom... 215 2e-54
UniRef50_Q8TFJ3 Cluster: Protein kinase A catalytic subunit; n=1... 214 3e-54
UniRef50_Q234E6 Cluster: Protein kinase domain containing protei... 214 4e-54
UniRef50_A0CUG4 Cluster: Chromosome undetermined scaffold_28, wh... 214 4e-54
UniRef50_Q6BHW6 Cluster: Debaryomyces hansenii chromosome G of s... 214 4e-54
UniRef50_Q6P5Z2 Cluster: Serine/threonine-protein kinase N3; n=2... 214 4e-54
UniRef50_Q8MUA6 Cluster: Protein kinase C-related kinase; n=1; H... 213 5e-54
UniRef50_Q4Q7M5 Cluster: Rac serine-threonine kinase, putative; ... 213 5e-54
UniRef50_UPI0000499138 Cluster: hypothetical protein 53.t00028; ... 213 6e-54
UniRef50_UPI000069F1C6 Cluster: UPI000069F1C6 related cluster; n... 213 6e-54
UniRef50_A7TMA2 Cluster: Putative uncharacterized protein; n=1; ... 213 6e-54
UniRef50_A5DZ73 Cluster: Putative uncharacterized protein; n=1; ... 213 6e-54
UniRef50_A0BD03 Cluster: Chromosome undetermined scaffold_10, wh... 213 8e-54
UniRef50_UPI00006CF9D0 Cluster: Protein kinase domain containing... 212 1e-53
UniRef50_A2ELF7 Cluster: AGC family protein kinase; n=4; Trichom... 212 1e-53
UniRef50_P36582 Cluster: Protein kinase C-like 1; n=2; Schizosac... 212 1e-53
UniRef50_UPI00015B57A5 Cluster: PREDICTED: similar to CG10261-PE... 212 1e-53
UniRef50_UPI00015B4E6B Cluster: PREDICTED: hypothetical protein;... 212 1e-53
UniRef50_UPI0000D5755E Cluster: PREDICTED: similar to ribosomal ... 212 1e-53
UniRef50_UPI000150AAA4 Cluster: Protein kinase domain containing... 211 2e-53
UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein kin... 211 2e-53
UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101, w... 211 2e-53
UniRef50_A4RL90 Cluster: Putative uncharacterized protein; n=1; ... 211 2e-53
UniRef50_A2G3R6 Cluster: AGC family protein kinase; n=3; Trichom... 210 3e-53
UniRef50_Q02956 Cluster: Protein kinase C zeta type; n=60; Bilat... 210 4e-53
UniRef50_UPI00006A0EC2 Cluster: UPI00006A0EC2 related cluster; n... 210 6e-53
UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative... 210 6e-53
UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|R... 210 6e-53
UniRef50_A2ECT2 Cluster: AGC family protein kinase; n=3; Trichom... 210 6e-53
UniRef50_P43057 Cluster: Protein kinase C-like 1; n=4; Saccharom... 210 6e-53
UniRef50_A0CP93 Cluster: Chromosome undetermined scaffold_23, wh... 209 8e-53
UniRef50_A5DM82 Cluster: Putative uncharacterized protein; n=1; ... 209 8e-53
UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA;... 209 1e-52
UniRef50_A2FDD2 Cluster: AGC family protein kinase; n=2; Trichom... 209 1e-52
UniRef50_A2E8U1 Cluster: AGC family protein kinase; n=1; Trichom... 209 1e-52
UniRef50_A2E224 Cluster: AGC family protein kinase; n=1; Trichom... 209 1e-52
UniRef50_O96942 Cluster: Serine /threonine protein kinase; n=1; ... 208 1e-52
UniRef50_A2EEZ5 Cluster: AGC family protein kinase; n=2; Trichom... 208 1e-52
UniRef50_UPI000065FBEC Cluster: Ribosomal protein S6 kinase alph... 208 2e-52
UniRef50_A0EIN6 Cluster: Chromosome undetermined scaffold_99, wh... 208 2e-52
UniRef50_UPI00006CFE83 Cluster: Protein kinase domain containing... 207 3e-52
UniRef50_A0DDH0 Cluster: Chromosome undetermined scaffold_46, wh... 207 3e-52
UniRef50_A0CSN3 Cluster: Chromosome undetermined scaffold_26, wh... 207 3e-52
UniRef50_UPI00006CD5AE Cluster: Protein kinase domain containing... 207 4e-52
UniRef50_A2DW86 Cluster: AGC family protein kinase; n=1; Trichom... 207 4e-52
UniRef50_UPI00006CFF91 Cluster: Protein kinase domain containing... 206 5e-52
UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to cGMP-depen... 206 5e-52
UniRef50_P24583 Cluster: Protein kinase C-like 1; n=5; Ascomycot... 206 9e-52
UniRef50_A2DV83 Cluster: AGC family protein kinase; n=1; Trichom... 205 1e-51
UniRef50_Q59EH6 Cluster: 3-phosphoinositide dependent protein ki... 205 1e-51
UniRef50_O15530 Cluster: 3-phosphoinositide-dependent protein ki... 205 1e-51
UniRef50_Q22LX8 Cluster: Protein kinase domain containing protei... 205 2e-51
UniRef50_UPI00006A08A1 Cluster: Serine/threonine-protein kinase ... 204 2e-51
UniRef50_P34100 Cluster: Developmentally-regulated protein kinas... 204 3e-51
UniRef50_Q23NJ5 Cluster: Protein kinase domain containing protei... 204 4e-51
UniRef50_A0EEZ4 Cluster: Chromosome undetermined scaffold_92, wh... 204 4e-51
UniRef50_UPI00006CB12C Cluster: Protein kinase domain containing... 203 5e-51
UniRef50_A2E5K8 Cluster: AGC family protein kinase; n=1; Trichom... 203 5e-51
UniRef50_A0C5F6 Cluster: Chromosome undetermined scaffold_15, wh... 203 5e-51
UniRef50_UPI000069DCCB Cluster: UPI000069DCCB related cluster; n... 203 7e-51
UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep:... 203 7e-51
UniRef50_A2FNQ5 Cluster: AGC family protein kinase; n=1; Trichom... 203 7e-51
UniRef50_A0E1G0 Cluster: Chromosome undetermined scaffold_73, wh... 203 7e-51
UniRef50_Q8SRK8 Cluster: Probable cAMP-dependent protein kinase ... 203 7e-51
UniRef50_Q9FXQ0 Cluster: Cyclic nucreotide dependent protein kin... 202 9e-51
UniRef50_Q18846 Cluster: Putative ribosomal protein S6 kinase al... 202 9e-51
UniRef50_A2FIJ5 Cluster: AGC family protein kinase; n=1; Trichom... 202 1e-50
UniRef50_A2E474 Cluster: AGC family protein kinase; n=1; Trichom... 202 1e-50
UniRef50_A0BN99 Cluster: Chromosome undetermined scaffold_118, w... 202 1e-50
UniRef50_UPI00006CBA83 Cluster: Protein kinase domain containing... 202 2e-50
UniRef50_Q4SK04 Cluster: Chromosome 10 SCAF14571, whole genome s... 202 2e-50
UniRef50_A0BQE1 Cluster: Chromosome undetermined scaffold_120, w... 202 2e-50
UniRef50_A0D9C4 Cluster: Chromosome undetermined scaffold_42, wh... 201 3e-50
UniRef50_P25098 Cluster: Beta-adrenergic receptor kinase 1; n=65... 201 3e-50
UniRef50_Q4RPP3 Cluster: Chromosome 12 SCAF15007, whole genome s... 200 3e-50
UniRef50_Q24GE7 Cluster: Protein kinase domain containing protei... 200 3e-50
UniRef50_A2ET74 Cluster: AGC family protein kinase; n=1; Trichom... 200 3e-50
UniRef50_Q6FJ43 Cluster: Similar to sp|P24583 Saccharomyces cere... 200 3e-50
UniRef50_UPI00006CB3D2 Cluster: Protein kinase domain containing... 200 5e-50
UniRef50_Q6BPN3 Cluster: Similar to sp|P38070 Saccharomyces cere... 200 5e-50
UniRef50_UPI0000499488 Cluster: hypothetical protein 137.t00011;... 200 6e-50
UniRef50_Q233E6 Cluster: Protein kinase domain containing protei... 200 6e-50
UniRef50_A0E888 Cluster: Chromosome undetermined scaffold_82, wh... 200 6e-50
UniRef50_A0BSF2 Cluster: Chromosome undetermined scaffold_125, w... 200 6e-50
UniRef50_UPI00015B53AD Cluster: PREDICTED: similar to RHO kinase... 199 8e-50
UniRef50_Q4RRU3 Cluster: Chromosome 7 SCAF15001, whole genome sh... 199 1e-49
UniRef50_A0DYT2 Cluster: Chromosome undetermined scaffold_7, who... 199 1e-49
UniRef50_A0DBI9 Cluster: Chromosome undetermined scaffold_44, wh... 199 1e-49
UniRef50_Q7PTH7 Cluster: ENSANGP00000010728; n=2; Culicidae|Rep:... 198 1e-49
UniRef50_Q5VT25 Cluster: Serine/threonine-protein kinase MRCK al... 198 1e-49
UniRef50_Q5SP91 Cluster: Novel protein similar to rho-associated... 198 2e-49
UniRef50_A2DB15 Cluster: AGC family protein kinase; n=1; Trichom... 198 2e-49
UniRef50_A0DZS8 Cluster: Chromosome undetermined scaffold_70, wh... 198 2e-49
UniRef50_UPI000065F79D Cluster: Protein kinase C delta type (EC ... 197 3e-49
UniRef50_A0BQV0 Cluster: Chromosome undetermined scaffold_121, w... 197 3e-49
UniRef50_A0BFR1 Cluster: Chromosome undetermined scaffold_104, w... 197 3e-49
UniRef50_A0BGU9 Cluster: Chromosome undetermined scaffold_107, w... 197 4e-49
UniRef50_Q23DN8 Cluster: Cyclic nucleotide-binding domain contai... 196 6e-49
UniRef50_O75116 Cluster: Rho-associated protein kinase 2; n=115;... 196 6e-49
UniRef50_Q16IB8 Cluster: Myotonin-protein kinase; n=3; cellular ... 196 8e-49
UniRef50_Q01B06 Cluster: CAMP-dependent protein kinase catalytic... 196 1e-48
UniRef50_Q9W1B0 Cluster: CG4012-PA; n=3; Sophophora|Rep: CG4012-... 196 1e-48
UniRef50_A0DTA2 Cluster: Chromosome undetermined scaffold_62, wh... 196 1e-48
UniRef50_UPI0000499007 Cluster: hypothetical protein 139.t00021;... 195 1e-48
UniRef50_Q9BMX6 Cluster: Phosphoinositide-dependent protein kina... 195 1e-48
UniRef50_A0EFE8 Cluster: Chromosome undetermined scaffold_93, wh... 195 1e-48
UniRef50_A2EE93 Cluster: AGC family protein kinase; n=1; Trichom... 195 2e-48
UniRef50_A0DBI7 Cluster: Chromosome undetermined scaffold_44, wh... 195 2e-48
UniRef50_Q4SLR2 Cluster: Chromosome 15 SCAF14556, whole genome s... 194 2e-48
UniRef50_A3KP71 Cluster: Prkcq protein; n=4; Clupeocephala|Rep: ... 194 2e-48
UniRef50_P92199 Cluster: Lethal protein 502; n=2; Caenorhabditis... 194 2e-48
UniRef50_A0C3V8 Cluster: Chromosome undetermined scaffold_148, w... 194 2e-48
UniRef50_Q4S6S5 Cluster: Chromosome 14 SCAF14723, whole genome s... 194 3e-48
UniRef50_Q23G03 Cluster: Protein kinase domain containing protei... 194 3e-48
UniRef50_A0E2Q8 Cluster: Chromosome undetermined scaffold_75, wh... 194 3e-48
UniRef50_UPI0000E4822C Cluster: PREDICTED: similar to KIAA0619 p... 194 4e-48
UniRef50_UPI00006CFBB4 Cluster: Protein kinase domain containing... 194 4e-48
UniRef50_A2EWI0 Cluster: AGC family protein kinase; n=2; Trichom... 194 4e-48
UniRef50_UPI00006CB658 Cluster: Protein kinase domain containing... 193 5e-48
UniRef50_UPI00006D0072 Cluster: Protein kinase domain containing... 192 1e-47
UniRef50_Q7R3M3 Cluster: GLP_39_70935_69175; n=2; Giardia intest... 192 1e-47
UniRef50_A0DGH3 Cluster: Chromosome undetermined scaffold_5, who... 192 2e-47
UniRef50_A0D329 Cluster: Chromosome undetermined scaffold_36, wh... 192 2e-47
UniRef50_UPI0000DB6D76 Cluster: PREDICTED: similar to genghis kh... 191 2e-47
UniRef50_UPI00006CAF21 Cluster: Protein kinase domain containing... 191 2e-47
UniRef50_Q24FD5 Cluster: Protein kinase domain containing protei... 191 2e-47
UniRef50_Q237P3 Cluster: Protein kinase domain containing protei... 191 2e-47
UniRef50_A0E0G1 Cluster: Chromosome undetermined scaffold_71, wh... 191 2e-47
UniRef50_A0DCJ0 Cluster: Chromosome undetermined scaffold_45, wh... 191 2e-47
UniRef50_A0D680 Cluster: Chromosome undetermined scaffold_39, wh... 191 2e-47
UniRef50_A0C4H5 Cluster: Chromosome undetermined scaffold_149, w... 191 2e-47
UniRef50_A2EX40 Cluster: AGC family protein kinase; n=4; Trichom... 191 3e-47
UniRef50_Q3SEP0 Cluster: CGMP-dependent protein kinase 8-2; n=8;... 190 4e-47
UniRef50_O01583 Cluster: Temporarily assigned gene name protein ... 190 4e-47
UniRef50_A0EAF2 Cluster: Chromosome undetermined scaffold_86, wh... 190 5e-47
UniRef50_A0DXD7 Cluster: Chromosome undetermined scaffold_68, wh... 190 5e-47
UniRef50_UPI00006CC414 Cluster: Protein kinase domain containing... 190 7e-47
UniRef50_A2FBN5 Cluster: AGC family protein kinase; n=1; Trichom... 190 7e-47
UniRef50_A0BPA1 Cluster: Chromosome undetermined scaffold_12, wh... 190 7e-47
UniRef50_Q22XQ2 Cluster: Protein kinase domain containing protei... 188 2e-46
UniRef50_A0E6L8 Cluster: Chromosome undetermined scaffold_8, who... 188 2e-46
UniRef50_A0E5D2 Cluster: Chromosome undetermined scaffold_79, wh... 188 2e-46
UniRef50_Q22RR1 Cluster: Protein kinase domain containing protei... 188 2e-46
UniRef50_A0BCG0 Cluster: Chromosome undetermined scaffold_10, wh... 187 3e-46
UniRef50_Q5KM47 Cluster: CAMP-dependent protein kinase, putative... 187 3e-46
UniRef50_A5AA56 Cluster: Putative Rho-associated kinase; n=1; Hy... 187 5e-46
UniRef50_A0BWJ4 Cluster: Chromosome undetermined scaffold_132, w... 187 5e-46
UniRef50_Q6DT37 Cluster: Serine/threonine-protein kinase MRCK ga... 187 5e-46
UniRef50_UPI000065FF34 Cluster: Homolog of Homo sapiens "Protein... 186 6e-46
UniRef50_P34947 Cluster: G protein-coupled receptor kinase 5; n=... 186 6e-46
UniRef50_UPI0000EB1830 Cluster: Serine/threonine-protein kinase ... 186 1e-45
UniRef50_A0E525 Cluster: Chromosome undetermined scaffold_79, wh... 186 1e-45
UniRef50_A0DDW7 Cluster: Chromosome undetermined scaffold_47, wh... 186 1e-45
UniRef50_UPI00006A0113 Cluster: UPI00006A0113 related cluster; n... 185 1e-45
UniRef50_UPI00006A01A3 Cluster: UPI00006A01A3 related cluster; n... 185 2e-45
UniRef50_A7QZS3 Cluster: Chromosome chr13 scaffold_286, whole ge... 185 2e-45
UniRef50_UPI00006CCD64 Cluster: Protein kinase domain containing... 184 2e-45
UniRef50_A2DP41 Cluster: AGC family protein kinase; n=1; Trichom... 184 2e-45
UniRef50_Q5AAN6 Cluster: Likely protein kinase; n=1; Candida alb... 184 2e-45
UniRef50_UPI00006A1147 Cluster: UPI00006A1147 related cluster; n... 184 3e-45
UniRef50_Q4T021 Cluster: Chromosome undetermined SCAF11390, whol... 184 3e-45
UniRef50_Q4DXB5 Cluster: Protein kinase, putative; n=3; Trypanos... 184 3e-45
UniRef50_A0C8J6 Cluster: Chromosome undetermined scaffold_158, w... 184 3e-45
UniRef50_UPI00006A16D5 Cluster: UPI00006A16D5 related cluster; n... 183 6e-45
UniRef50_Q9XF67 Cluster: 3-phosphoinositide-dependent protein ki... 183 7e-45
UniRef50_Q9VXE3 Cluster: CG9774-PA; n=8; Endopterygota|Rep: CG97... 183 7e-45
UniRef50_Q4QIJ7 Cluster: Serine/threonine kinase, putative; n=13... 183 7e-45
UniRef50_A2FZ96 Cluster: AGC family protein kinase; n=1; Trichom... 183 7e-45
UniRef50_A2EY79 Cluster: AGC family protein kinase; n=1; Trichom... 183 7e-45
UniRef50_A0D032 Cluster: Chromosome undetermined scaffold_329, w... 183 7e-45
UniRef50_Q5C2X7 Cluster: SJCHGC09382 protein; n=1; Schistosoma j... 182 1e-44
UniRef50_A0C2B1 Cluster: Chromosome undetermined scaffold_144, w... 182 1e-44
UniRef50_A4R181 Cluster: Putative uncharacterized protein; n=1; ... 182 2e-44
UniRef50_A0BYR7 Cluster: Chromosome undetermined scaffold_137, w... 181 2e-44
UniRef50_A0EAJ3 Cluster: Chromosome undetermined scaffold_86, wh... 181 3e-44
UniRef50_A0DTB0 Cluster: Chromosome undetermined scaffold_62, wh... 181 3e-44
UniRef50_A2GBV0 Cluster: AGC family protein kinase; n=1; Trichom... 180 4e-44
UniRef50_A0C6X0 Cluster: Chromosome undetermined scaffold_153, w... 180 4e-44
UniRef50_A0BCL5 Cluster: Chromosome undetermined scaffold_10, wh... 180 5e-44
UniRef50_UPI000049857F Cluster: protein kinase; n=1; Entamoeba h... 180 7e-44
UniRef50_A0CIE7 Cluster: Chromosome undetermined scaffold_19, wh... 180 7e-44
UniRef50_Q4T9Z5 Cluster: Chromosome undetermined SCAF7480, whole... 179 9e-44
UniRef50_Q6E6E4 Cluster: Protein kinase C; n=1; Antonospora locu... 179 9e-44
UniRef50_UPI0001509E5E Cluster: Streptococcal surface antigen re... 179 1e-43
UniRef50_UPI00006CBF34 Cluster: Protein kinase domain containing... 178 2e-43
UniRef50_Q54UZ1 Cluster: Putative uncharacterized protein; n=1; ... 178 2e-43
UniRef50_Q9FJ55 Cluster: Serine/threonine protein kinase; n=14; ... 178 2e-43
UniRef50_A2FY70 Cluster: AGC family protein kinase; n=1; Trichom... 178 2e-43
UniRef50_O14578 Cluster: Citron Rho-interacting kinase; n=56; Eu... 178 2e-43
UniRef50_UPI000049A425 Cluster: hypothetical protein 134.t00004;... 177 3e-43
UniRef50_A2GEQ5 Cluster: AGC family protein kinase; n=1; Trichom... 177 4e-43
UniRef50_A0DYJ0 Cluster: Chromosome undetermined scaffold_7, who... 177 4e-43
UniRef50_A2G1Q9 Cluster: AGC family protein kinase; n=1; Trichom... 177 5e-43
UniRef50_A2FYT0 Cluster: AGC family protein kinase; n=2; Trichom... 177 5e-43
UniRef50_Q8SSJ0 Cluster: PROTEIN KINASE C; n=1; Encephalitozoon ... 176 9e-43
UniRef50_P38991 Cluster: Spindle assembly checkpoint kinase; n=5... 176 9e-43
UniRef50_A2EJ98 Cluster: AGC family protein kinase; n=2; Trichom... 175 1e-42
UniRef50_Q23TE4 Cluster: Protein kinase domain containing protei... 175 2e-42
UniRef50_A0C404 Cluster: Chromosome undetermined scaffold_148, w... 175 2e-42
UniRef50_A0BZI1 Cluster: Chromosome undetermined scaffold_139, w... 174 3e-42
UniRef50_A7PMI1 Cluster: Chromosome chr14 scaffold_21, whole gen... 174 3e-42
UniRef50_A2X165 Cluster: Putative uncharacterized protein; n=2; ... 174 3e-42
UniRef50_Q54WX4 Cluster: Putative uncharacterized protein aurB; ... 174 3e-42
UniRef50_UPI00006A21D0 Cluster: UPI00006A21D0 related cluster; n... 173 5e-42
UniRef50_A0DIF4 Cluster: Chromosome undetermined scaffold_51, wh... 173 5e-42
UniRef50_Q96NX5 Cluster: Calcium/calmodulin-dependent protein ki... 173 5e-42
UniRef50_A7QA52 Cluster: Chromosome undetermined scaffold_69, wh... 173 6e-42
UniRef50_Q6BFK9 Cluster: SNF1-related protein kinase, putative; ... 173 6e-42
UniRef50_Q54PK9 Cluster: Putative uncharacterized protein pdkB; ... 173 6e-42
UniRef50_Q6CPN3 Cluster: Similar to sgd|S0002874 Saccharomyces c... 173 8e-42
UniRef50_Q15835 Cluster: Rhodopsin kinase precursor; n=28; Eutel... 173 8e-42
UniRef50_UPI000069FC08 Cluster: UPI000069FC08 related cluster; n... 172 1e-41
UniRef50_A2F8E8 Cluster: AGC family protein kinase; n=1; Trichom... 172 1e-41
UniRef50_UPI000150AA6C Cluster: Protein kinase domain containing... 172 1e-41
UniRef50_UPI0000499714 Cluster: protein kinase; n=3; Entamoeba h... 172 1e-41
UniRef50_O22932 Cluster: CBL-interacting serine/threonine-protei... 172 1e-41
UniRef50_A0BCA7 Cluster: Chromosome undetermined scaffold_10, wh... 171 2e-41
UniRef50_Q21483 Cluster: Putative uncharacterized protein; n=2; ... 171 2e-41
UniRef50_Q6BVA0 Cluster: Spindle assembly checkpoint kinase; n=1... 171 2e-41
UniRef50_Q9MAM1 Cluster: T25K16.13; n=9; Brassicaceae|Rep: T25K1... 171 3e-41
UniRef50_A0BT25 Cluster: Chromosome undetermined scaffold_126, w... 170 4e-41
UniRef50_UPI000069F567 Cluster: UPI000069F567 related cluster; n... 170 6e-41
UniRef50_Q4Q9K2 Cluster: Serine/threonine-protein kinase, putati... 170 6e-41
UniRef50_A7TL28 Cluster: Putative uncharacterized protein; n=1; ... 170 6e-41
UniRef50_Q9SLZ5 Cluster: OsPK7; n=14; Magnoliophyta|Rep: OsPK7 -... 169 7e-41
UniRef50_A2FYJ4 Cluster: AGC family protein kinase; n=1; Trichom... 169 7e-41
UniRef50_A0CPK1 Cluster: Chromosome undetermined scaffold_23, wh... 169 7e-41
UniRef50_A1DMX3 Cluster: Protein kinase, putative; n=11; Pezizom... 169 7e-41
UniRef50_UPI00015B638D Cluster: PREDICTED: similar to aurora kin... 169 1e-40
UniRef50_UPI000069DCF9 Cluster: UPI000069DCF9 related cluster; n... 169 1e-40
UniRef50_UPI000069E61F Cluster: UPI000069E61F related cluster; n... 168 2e-40
UniRef50_A7QFL3 Cluster: Chromosome chr8 scaffold_88, whole geno... 168 2e-40
UniRef50_Q6C3J2 Cluster: Spindle assembly checkpoint kinase; n=1... 168 2e-40
UniRef50_Q94DT7 Cluster: OsPK4-like protein; n=4; Oryza sativa|R... 168 2e-40
UniRef50_Q6BG36 Cluster: SNF1-related protein kinase, putative; ... 168 2e-40
UniRef50_Q00TK7 Cluster: Protein kinase, putative; n=2; Ostreoco... 167 3e-40
UniRef50_Q7PNN7 Cluster: ENSANGP00000021780; n=1; Anopheles gamb... 167 3e-40
UniRef50_Q753H7 Cluster: AFR335Cp; n=1; Eremothecium gossypii|Re... 167 4e-40
UniRef50_A2ETF3 Cluster: CAMK family protein kinase; n=1; Tricho... 167 5e-40
UniRef50_A0DGQ2 Cluster: Chromosome undetermined scaffold_5, who... 167 5e-40
UniRef50_A0BP84 Cluster: Chromosome undetermined scaffold_12, wh... 166 7e-40
UniRef50_Q9VTY8 Cluster: CG10522-PA; n=4; Sophophora|Rep: CG1052... 165 1e-39
UniRef50_Q8SWT6 Cluster: RE56868p; n=4; Drosophila melanogaster|... 165 1e-39
UniRef50_A0E1E2 Cluster: Chromosome undetermined scaffold_73, wh... 165 1e-39
UniRef50_Q0UF87 Cluster: Putative uncharacterized protein; n=2; ... 165 1e-39
UniRef50_Q84QE0 Cluster: Avr9/Cf-9 rapidly elicited protein 216;... 165 2e-39
UniRef50_A0E675 Cluster: Chromosome undetermined scaffold_8, who... 165 2e-39
UniRef50_A0DMA4 Cluster: Chromosome undetermined scaffold_56, wh... 165 2e-39
UniRef50_Q38997 Cluster: SNF1-related protein kinase catalytic s... 165 2e-39
UniRef50_Q9NRH2 Cluster: SNF-related serine/threonine-protein ki... 165 2e-39
UniRef50_UPI00015B4C4D Cluster: PREDICTED: similar to p90 riboso... 164 4e-39
UniRef50_A0DUI6 Cluster: Chromosome undetermined scaffold_64, wh... 164 4e-39
UniRef50_A0D1D1 Cluster: Chromosome undetermined scaffold_34, wh... 164 4e-39
UniRef50_Q6DI71 Cluster: Dmpk protein; n=4; Murinae|Rep: Dmpk pr... 163 5e-39
UniRef50_Q3LDS4 Cluster: Carbon catabolite derepressing protein ... 163 5e-39
UniRef50_A2GCT3 Cluster: CAMK family protein kinase; n=1; Tricho... 163 5e-39
UniRef50_A5DT22 Cluster: Putative uncharacterized protein; n=1; ... 163 5e-39
UniRef50_A6NEJ5 Cluster: Uncharacterized protein SGK3; n=9; Euth... 163 6e-39
UniRef50_Q7Z865 Cluster: Protein kinase; n=1; Kluyveromyces lact... 163 6e-39
UniRef50_O00444 Cluster: Serine/threonine-protein kinase PLK4; n... 163 6e-39
UniRef50_A2VDZ4 Cluster: PLK4 protein; n=3; Mammalia|Rep: PLK4 p... 163 9e-39
UniRef50_Q1XHM0 Cluster: G protein-coupled receptor kinase 1A; n... 162 1e-38
UniRef50_Q0D3M5 Cluster: Os07g0678300 protein; n=3; Oryza sativa... 162 1e-38
UniRef50_Q9Y7J6 Cluster: Serine/threonine-protein kinase ppk21; ... 162 1e-38
UniRef50_Q4Q898 Cluster: Zinc finger protein kinase-like; n=3; L... 162 1e-38
UniRef50_A2EZG8 Cluster: AGC family protein kinase; n=1; Trichom... 162 1e-38
UniRef50_UPI000065EE71 Cluster: MAP/microtubule affinity-regulat... 161 2e-38
UniRef50_Q6V8K6 Cluster: Gliding motility related CaM kinase; n=... 161 2e-38
UniRef50_Q22DW7 Cluster: Protein kinase domain containing protei... 161 2e-38
UniRef50_A2DBY9 Cluster: CAMK family protein kinase; n=2; Tricho... 161 2e-38
UniRef50_UPI00006A17F7 Cluster: UPI00006A17F7 related cluster; n... 161 3e-38
UniRef50_P25323 Cluster: Myosin light chain kinase; n=4; Dictyos... 161 3e-38
UniRef50_O08679 Cluster: Serine/threonine-protein kinase MARK2; ... 161 3e-38
UniRef50_UPI000065E88B Cluster: Serine/threonine-protein kinase ... 161 3e-38
UniRef50_Q6P954 Cluster: Zgc:73231; n=2; Danio rerio|Rep: Zgc:73... 161 3e-38
UniRef50_UPI00004D65ED Cluster: UPI00004D65ED related cluster; n... 160 5e-38
UniRef50_UPI00004D2369 Cluster: UPI00004D2369 related cluster; n... 160 5e-38
UniRef50_A4S6U9 Cluster: Predicted protein; n=2; Ostreococcus|Re... 160 5e-38
UniRef50_Q16NS1 Cluster: Citron ser/thr kinase; n=3; Culicidae|R... 160 5e-38
UniRef50_Q5DGA7 Cluster: SJCHGC00915 protein; n=1; Schistosoma j... 160 6e-38
UniRef50_Q64702 Cluster: Serine/threonine-protein kinase PLK4; n... 160 6e-38
UniRef50_Q5DTG3 Cluster: MKIAA4230 protein; n=16; Bilateria|Rep:... 159 8e-38
UniRef50_Q7QXR8 Cluster: GLP_399_8255_9553; n=1; Giardia lamblia... 159 8e-38
UniRef50_A4VDB2 Cluster: Serine/threonine protein kinase; n=1; T... 159 8e-38
UniRef50_Q9P0L2 Cluster: Serine/threonine-protein kinase MARK1; ... 159 8e-38
UniRef50_Q8IU85 Cluster: Calcium/calmodulin-dependent protein ki... 159 8e-38
UniRef50_UPI0000519D29 Cluster: PREDICTED: similar to maternal e... 159 1e-37
UniRef50_Q4SL09 Cluster: Chromosome 17 SCAF14563, whole genome s... 159 1e-37
UniRef50_Q96L34 Cluster: MAP/microtubule affinity-regulating kin... 159 1e-37
UniRef50_Q9LDI3 Cluster: CBL-interacting serine/threonine-protei... 159 1e-37
UniRef50_Q4RR91 Cluster: Chromosome 14 SCAF15003, whole genome s... 159 1e-37
UniRef50_Q8MVX2 Cluster: Putative serine/threonine protein kinas... 158 2e-37
UniRef50_Q27393 Cluster: Aurora; n=7; Fungi/Metazoa group|Rep: A... 158 2e-37
UniRef50_A2EBI4 Cluster: CAMK family protein kinase; n=1; Tricho... 158 2e-37
UniRef50_P32866 Cluster: G protein-coupled receptor kinase 2; n=... 158 2e-37
UniRef50_UPI00015B5903 Cluster: PREDICTED: similar to Melk prote... 157 3e-37
UniRef50_Q9W532 Cluster: CG4290-PA; n=8; Coelomata|Rep: CG4290-P... 157 3e-37
UniRef50_A2DAR5 Cluster: AGC family protein kinase; n=1; Trichom... 157 3e-37
UniRef50_A0D0C4 Cluster: Chromosome undetermined scaffold_33, wh... 157 3e-37
UniRef50_UPI000069EAF4 Cluster: UPI000069EAF4 related cluster; n... 157 4e-37
UniRef50_A0E900 Cluster: Chromosome undetermined scaffold_83, wh... 157 4e-37
UniRef50_P92937 Cluster: CBL-interacting serine/threonine-protei... 157 4e-37
UniRef50_Q4E2T3 Cluster: Protein kinase, putative; n=1; Trypanos... 157 6e-37
UniRef50_Q232Y5 Cluster: Protein kinase domain containing protei... 157 6e-37
UniRef50_UPI000069D92E Cluster: UPI000069D92E related cluster; n... 156 7e-37
UniRef50_A2ET53 Cluster: CAMK family protein kinase; n=1; Tricho... 156 7e-37
UniRef50_A0CGU4 Cluster: Chromosome undetermined scaffold_18, wh... 156 7e-37
UniRef50_A0BMD5 Cluster: Chromosome undetermined scaffold_116, w... 156 7e-37
UniRef50_A0BDU3 Cluster: Chromosome undetermined scaffold_101, w... 156 7e-37
UniRef50_Q09537 Cluster: G protein-coupled receptor kinase 1; n=... 156 7e-37
UniRef50_O59790 Cluster: Serine/threonine-protein kinase ark1; n... 156 7e-37
UniRef50_A0EBP2 Cluster: Chromosome undetermined scaffold_88, wh... 156 1e-36
UniRef50_A0E8Y3 Cluster: Chromosome undetermined scaffold_83, wh... 156 1e-36
UniRef50_P54646 Cluster: 5'-AMP-activated protein kinase catalyt... 156 1e-36
>UniRef50_P17612 Cluster: cAMP-dependent protein kinase,
alpha-catalytic subunit; n=158; Bilateria|Rep:
cAMP-dependent protein kinase, alpha-catalytic subunit -
Homo sapiens (Human)
Length = 351
Score = 457 bits (1127), Expect = e-127
Identities = 196/341 (57%), Positives = 270/341 (79%)
Query: 26 AKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYY 85
++QE ++L K ++DF++ W+ +++ A L+ FER K LGTG+FG V LVKH TG +Y
Sbjct: 11 SEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHY 70
Query: 86 AMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMF 145
AMK+L+K+K+V+LKQIEH+ EK+IL +NFPF+V +++ FKDN LY V+ ++ GGEMF
Sbjct: 71 AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMF 130
Query: 146 SHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK 205
SHLR++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID+ GYI++TDFGF K
Sbjct: 131 SHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK 190
Query: 206 LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK 265
++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEK
Sbjct: 191 RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 266 IVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSR 325
IV+GK R PSHFS +LKD++ ++LQVD T+R+G LK+GV D KNHKWF DW +I +
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310
Query: 326 IHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
+ PF PK + PGDT+NFD ++EE+I+ S +EF++F
Sbjct: 311 VEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
>UniRef50_Q17JG1 Cluster: Camp-dependent protein kinase catalytic
subunit; n=1; Aedes aegypti|Rep: Camp-dependent protein
kinase catalytic subunit - Aedes aegypti (Yellowfever
mosquito)
Length = 405
Score = 418 bits (1030), Expect = e-115
Identities = 190/340 (55%), Positives = 251/340 (73%), Gaps = 3/340 (0%)
Query: 30 QYSQYLKKLRQDFVESWDD-KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
+Y Q L +L+ DF + +++ K+ S L D++ K LGTGAFG+V L++ T +Y+A+K
Sbjct: 66 EYKQILNRLKVDFEKKYNNVKASSGNGLQDYDVLKTLGTGAFGVVKLIRRKNTEEYFALK 125
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
+L KEKIVR KQ++H+ EK+IL + FPF+V M+ FKDN Y+Y V+PF+ GGEMF+ L
Sbjct: 126 ILSKEKIVRHKQLQHTANEKRILQSVEFPFLVNMECCFKDNSYIYLVMPFVCGGEMFALL 185
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR 208
RK +F E AKFYGAQV LA+EYLH L+YRDLKPENILID GY+KITDFGFCKLIR
Sbjct: 186 RKSKRFGEEQAKFYGAQVALAIEYLHHMNLIYRDLKPENILIDMKGYVKITDFGFCKLIR 245
Query: 209 GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFF--ASDPMRIYEKI 266
RTWTLCGTPEYLAPEII SKGYG SVDWWS G+LL+EM+AG+ PF+ +SD M ++EKI
Sbjct: 246 DRTWTLCGTPEYLAPEIIQSKGYGKSVDWWSFGILLYEMAAGYTPFYTNSSDHMVLFEKI 305
Query: 267 VAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRI 326
GK+R P+ F +LK +I ++L D TRR+G LK+G D K H WFR +W ++N +
Sbjct: 306 CKGKFRFPAGFGGDLKHLIQNILHADLTRRFGNLKNGANDIKQHIWFRGTNWIGLMNMEV 365
Query: 327 HPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
PF PKI PGD + FD++DE+ +K + C++ +EFADF
Sbjct: 366 SAPFIPKISGPGDASQFDIYDEQDLKIASKCMFIKEFADF 405
>UniRef50_P22612 Cluster: cAMP-dependent protein kinase,
gamma-catalytic subunit; n=18; Coelomata|Rep:
cAMP-dependent protein kinase, gamma-catalytic subunit -
Homo sapiens (Human)
Length = 351
Score = 414 bits (1020), Expect = e-114
Identities = 181/350 (51%), Positives = 260/350 (74%), Gaps = 5/350 (1%)
Query: 22 GYSPAK-----QEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLV 76
G +PAK +E +++L K R DF+ W + +++ A + FER + LG G+FG V LV
Sbjct: 2 GNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLV 61
Query: 77 KHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVL 136
+H TG +YAMK+L K+K+V++KQ+EH EK+IL ++FPF+V +++ FKDN YLY V+
Sbjct: 62 RHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVM 121
Query: 137 PFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYI 196
++ GGEMFS L+++G+F E A FY AQV+LA++YLH+ +L++RDLKPEN+LID+ GY+
Sbjct: 122 EYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYL 181
Query: 197 KITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFA 256
++TDFGF K ++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+ G PPF+A
Sbjct: 182 QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYA 241
Query: 257 SDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREI 316
P++IYEKIV+G+ R PS S +LK ++ +LQVD T+R+G L++GV D KNHKWF
Sbjct: 242 DQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATT 301
Query: 317 DWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
W +I ++ PF PK PGD +NFD ++EE+++ S +EF++F
Sbjct: 302 SWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF 351
>UniRef50_P34099 Cluster: cAMP-dependent protein kinase catalytic
subunit; n=23; Eukaryota|Rep: cAMP-dependent protein
kinase catalytic subunit - Dictyostelium discoideum
(Slime mold)
Length = 648
Score = 369 bits (907), Expect = e-101
Identities = 168/332 (50%), Positives = 235/332 (70%), Gaps = 2/332 (0%)
Query: 26 AKQEQYSQYLKKLRQDFVESWDDKSESNAK--LNDFERQKVLGTGAFGIVFLVKHIVTGK 83
++Q+ Q L+++ V S+ NA+ L +F++ +VLGTG FG V+L+++ G
Sbjct: 301 SQQQLQQQQLQQIPPPTVNSFFLPPPVNARERLKEFKQIRVLGTGTFGKVYLIQNTKDGC 360
Query: 84 YYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGE 143
YYAMK L K +V+LKQ+EH EK IL ++ PF+V + F+D LY + ++AGGE
Sbjct: 361 YYAMKCLNKAYVVQLKQVEHLNSEKSILSSIHHPFIVNLYQAFQDEKKLYLLFEYVAGGE 420
Query: 144 MFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGF 203
+F+HLRK KF ++AKFY A+++LALE+LH +VYRDLKPEN+LID G+IKITDFGF
Sbjct: 421 VFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGF 480
Query: 204 CKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIY 263
K + RT+TLCGTPEYLAPEII SKG+G +VDWW+LG+L+FEM AG+PPF+ D IY
Sbjct: 481 AKRVEDRTFTLCGTPEYLAPEIIQSKGHGKAVDWWALGILIFEMLAGYPPFYDDDTFAIY 540
Query: 264 EKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILN 323
KI+AG+ P F V+ KD+I +L D TRR G LKDG LD KNH+WF +I+W+ +
Sbjct: 541 NKILAGRITFPLGFDVDAKDLIKRLLTADRTRRLGALKDGALDVKNHRWFSDINWERLYQ 600
Query: 324 SRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSP 355
R + PF PKI+ GD++NF+++DEE++ + P
Sbjct: 601 RRDNGPFIPKIQHQGDSSNFEMYDEEEMVEEP 632
>UniRef50_Q9VA47 Cluster: CG12069-PA; n=3; Sophophora|Rep:
CG12069-PA - Drosophila melanogaster (Fruit fly)
Length = 356
Score = 349 bits (857), Expect = 9e-95
Identities = 165/339 (48%), Positives = 225/339 (66%), Gaps = 3/339 (0%)
Query: 31 YSQYLKKLRQDFVESWDDKSES-NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKM 89
Y L KLR+DF + + + S + L+D+E + LG+G+FG V LV+ +G YYA K
Sbjct: 18 YILILDKLREDFNKKFATNTPSPSTGLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQ 77
Query: 90 LEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLR 149
L K++IV+ KQ+ H EK +L + FP V + +KD LY VLP I GGE+F++ R
Sbjct: 78 LSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHR 137
Query: 150 KMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG 209
K+ KF E A+FY AQV LALEYLH C L+YRDLKPENI++D+ GY+K+TDFGF K +
Sbjct: 138 KVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVET 197
Query: 210 RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFA--SDPMRIYEKIV 267
RT TLCGTPEYL PEII SK YG SVDWW+ GVL+FE AGH PF A D M +Y KI
Sbjct: 198 RTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKIC 257
Query: 268 AGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIH 327
Y+ PS+FS L+ ++ H+LQVD ++R+G L +G D K H+WF++++W +LN ++
Sbjct: 258 EADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVN 317
Query: 328 PPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
P+ P I +P D +NFD ++ + +EE FADF
Sbjct: 318 APYVPNISNPEDISNFDKVSDKPRPKAKTMRHEEAFADF 356
>UniRef50_Q4E4S9 Cluster: Protein kinase A catalytic subunit isoform
1, putative; n=8; Trypanosomatidae|Rep: Protein kinase A
catalytic subunit isoform 1, putative - Trypanosoma
cruzi
Length = 387
Score = 344 bits (846), Expect = 2e-93
Identities = 159/323 (49%), Positives = 227/323 (70%), Gaps = 3/323 (0%)
Query: 45 SWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHS 104
+++ SN KL DFE LGTG+FG V + K T YYA+K L+K +I+++KQ++H
Sbjct: 64 NYEKPDTSNWKLADFEMGDTLGTGSFGRVRIAKLKGTNDYYAVKCLKKREILKMKQVQHI 123
Query: 105 YYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGA 164
EK+IL L+ PF+V M F+D+ +Y+VL F+ GGEMF+HLR G+F AKFY A
Sbjct: 124 SQEKQILMELSHPFIVNMMCSFQDDRRVYFVLEFVVGGEMFTHLRSAGRFPNDVAKFYHA 183
Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPE 224
+++LA EYLH+ +++YRDLKPEN+L+D G++K+TDFGF K + RT+TLCGTPEYLAPE
Sbjct: 184 EIVLAFEYLHSKDIIYRDLKPENLLLDSKGHVKVTDFGFAKKVPERTFTLCGTPEYLAPE 243
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
+I SKG+G +VDWW++GVLL+E AG+PPF+ P R YEKI++G+++ PS F +D+
Sbjct: 244 VIQSKGHGKAVDWWTMGVLLYEFIAGYPPFYDDTPFRTYEKILSGRFKFPSWFDARARDL 303
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP-KIRSPGDTTNF 343
+ +LQ D T+R GTLK GV D KNH +F +W+ L +R +P P K +SPGDT+NF
Sbjct: 304 VKGLLQTDHTKRLGTLKGGVADVKNHPYFHGANWEK-LYARYYPAPIPVKAKSPGDTSNF 362
Query: 344 DVFDEEKIKDSPVCLYEEEFADF 366
+ + E + +D V L + A+F
Sbjct: 363 ERYPESQ-EDRAVPLTATQQAEF 384
>UniRef50_UPI000155CDCE Cluster: PREDICTED: similar to protein
kinase; n=2; Mammalia|Rep: PREDICTED: similar to protein
kinase - Ornithorhynchus anatinus
Length = 450
Score = 344 bits (845), Expect = 3e-93
Identities = 144/298 (48%), Positives = 213/298 (71%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
+ ER+++L TG FG V LVK Y+A+K++ ++RLKQ +H + EK +L +N P
Sbjct: 140 EVERRRLLSTGTFGRVHLVKERTAKHYFALKVMSIPDVIRLKQEQHVHNEKSVLKEVNHP 199
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F++ + + + D +LY ++ ++ GGE+FS+LR MG+F ++ FY ++I A+EY+H+ E
Sbjct: 200 FLIRLYWTYHDERFLYMLMEYVPGGELFSYLRNMGRFNNSTGLFYSTEIICAIEYIHSKE 259
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDW 237
+VYRDLKPENIL+D+ G+IK+TDFGF K + +TWTLCGTPEYLAPE+I SKG+G +VDW
Sbjct: 260 IVYRDLKPENILLDKEGHIKLTDFGFAKKLVDKTWTLCGTPEYLAPEVIQSKGHGRAVDW 319
Query: 238 WSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRY 297
W+LG+L+FEM +G PPFF +P IY+KI+AGK P H + +KD+I +L VD TRR
Sbjct: 320 WALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDLYVKDLIKKLLVVDRTRRL 379
Query: 298 GTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSP 355
G +K+G D K H+WFR IDW+++ ++ PP PK+ S GDT+NF+ + E+ +P
Sbjct: 380 GNMKNGADDVKRHRWFRSIDWEAVPQRKLKPPIVPKVSSDGDTSNFEAYPEDDWNKTP 437
>UniRef50_P51817 Cluster: Serine/threonine-protein kinase PRKX;
n=54; Eukaryota|Rep: Serine/threonine-protein kinase
PRKX - Homo sapiens (Human)
Length = 358
Score = 341 bits (838), Expect = 2e-92
Identities = 145/293 (49%), Positives = 208/293 (70%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF+ +GTG FG V LVK ++A+K++ ++RLKQ +H + EK +L ++
Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVS 105
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ + + + D +LY ++ ++ GGE+FS+LR G+F T+ FY A++I A+EYLH+
Sbjct: 106 HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHS 165
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSV 235
E+VYRDLKPENIL+DR G+IK+TDFGF K + RTWTLCGTPEYLAPE+I SKG+G +V
Sbjct: 166 KEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAV 225
Query: 236 DWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTR 295
DWW+LG+L+FEM +G PPFF +P IY+KI+AGK P H +KD+I +L VD TR
Sbjct: 226 DWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTR 285
Query: 296 RYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDE 348
R G +K+G D K+H+WFR +DW+++ ++ PP PKI GDT+NF+ + E
Sbjct: 286 RLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYPE 338
>UniRef50_Q8NIL1 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=6; Fungi|Rep: CAMP-dependent protein kinase
catalytic subunit - Cryptococcus neoformans var.
neoformans
Length = 516
Score = 332 bits (817), Expect = 6e-90
Identities = 148/305 (48%), Positives = 214/305 (70%), Gaps = 2/305 (0%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K+ L+DF ++ LGTG+FG V LV+ G++YA+K+L KEK++++KQ+EH+ E+
Sbjct: 194 KTAGRYALSDFLIERTLGTGSFGRVHLVRSRHNGRFYAVKVLNKEKVIKMKQVEHTNSER 253
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L + PF+V + F+D LY V+ F+AGGE+FS LRK +F + AKFY A+V L
Sbjct: 254 EMLVRVRHPFLVNLWGTFQDVNNLYMVMDFVAGGELFSLLRKSQRFPNSVAKFYAAEVAL 313
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILS 228
AL+YLH+ +++YRDLKPEN+L+ G++K+T+FGF K + TWTLCGTP+YLAPE++ S
Sbjct: 314 ALDYLHSLDIIYRDLKPENLLLGADGHVKVTNFGFAKYVPDITWTLCGTPDYLAPEVVQS 373
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASD--PMRIYEKIVAGKYRCPSHFSVELKDIIG 286
KGY SVDW++LGVL+FEM AG+PPFF D PM++YEKI+AGK R P++F K+++
Sbjct: 374 KGYNKSVDWYALGVLIFEMLAGYPPFFTEDGNPMKLYEKIIAGKVRYPTYFDALAKELLK 433
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
++L D T+RYG L+ G D H WF E+DWD + I P+ PKI GD + FD +
Sbjct: 434 NLLIGDLTKRYGNLRAGSSDIFAHGWFAEVDWDKLYRREIPAPYVPKIDGEGDASQFDRY 493
Query: 347 DEEKI 351
E +
Sbjct: 494 QEADV 498
>UniRef50_P40376 Cluster: cAMP-dependent protein kinase catalytic
subunit; n=1; Schizosaccharomyces pombe|Rep:
cAMP-dependent protein kinase catalytic subunit -
Schizosaccharomyces pombe (Fission yeast)
Length = 512
Score = 323 bits (794), Expect = 4e-87
Identities = 163/356 (45%), Positives = 227/356 (63%), Gaps = 11/356 (3%)
Query: 2 ADSEIKRHINSPRGDL-IQHGGYSPAKQEQYSQYLKKLR--------QDFVESWDDKSES 52
+ S +RH RG+L +HG A ++++K+R + + D ++
Sbjct: 135 SQSSHQRHSRDGRGELGSEHGERRSAMDGLRDRHIRKVRVSQLLDLQRRRIRPADHTTKD 194
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
+ DF + LGTG+FG V LV+ YYA+K+LEK+KIV +KQIEH+ E+ IL
Sbjct: 195 RYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILS 254
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
+ PF+ + F+D L+ V+ F GGE+FS LRK +F E AKFY A+VILAL+Y
Sbjct: 255 RVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDY 314
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR-GRTWTLCGTPEYLAPEIILSKGY 231
LH ++VYRDLKPEN+L+DR G++KI DFGF K + TLCGTP+YLAPEII K Y
Sbjct: 315 LHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCCTLCGTPDYLAPEIISLKPY 374
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
+ DWWSLG+L+FEM AG+PPF++ +PM++YE I+ GK PS+FS D++ H+LQ
Sbjct: 375 NKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLLQR 434
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS-PGDTTNFDVF 346
D T RYG LKDG +D H WFR+I WD IL +I P+ P I++ GD++ FD +
Sbjct: 435 DITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSSQFDAY 490
>UniRef50_Q9BMY6 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=1; Toxoplasma gondii|Rep: CAMP-dependent
protein kinase catalytic subunit - Toxoplasma gondii
Length = 394
Score = 317 bits (778), Expect = 3e-85
Identities = 154/345 (44%), Positives = 212/345 (61%), Gaps = 10/345 (2%)
Query: 25 PAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKY 84
P ++ SQ L ++R D + N ++DF + +GTG+FG V +V +
Sbjct: 54 PNVADRESQILSQVRYDLLAR-------NLSIDDFLFHETVGTGSFGRVCIVDLRGAAGW 106
Query: 85 Y---AMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAG 141
Y A+K+L K KIV++KQ+EH EK+IL + PF+V + F+D L+ ++ ++ G
Sbjct: 107 YPPMALKILSKHKIVKMKQVEHVKDEKRILSSIEHPFIVNLLAAFQDEKRLFILMEYVNG 166
Query: 142 GEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDF 201
GE+FSHLR+ A+ Y A++ LA +YLH +VYRDLKPEN+LID G+IKITDF
Sbjct: 167 GELFSHLRRRNCIPTDQARLYAAEITLAFQYLHQRHIVYRDLKPENLLIDSQGHIKITDF 226
Query: 202 GFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMR 261
GF K+++ RTWTLCGT EYLAPE I +G+G+ VDWW+LG+LLFEM AGHPPF +P+
Sbjct: 227 GFAKVVKDRTWTLCGTHEYLAPESITRRGHGLPVDWWALGILLFEMLAGHPPFVDENPLG 286
Query: 262 IYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSI 321
IY KI+AGK P F K ++ +L D +RYG LKDG D KNHK+F+ IDW
Sbjct: 287 IYRKIIAGKIEFPRSFDYAAKSLVKRLLTHDPLKRYGCLKDGAEDVKNHKFFKGIDWVKC 346
Query: 322 LNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
N I P+ P R P D++ FD + E SP E+ A F
Sbjct: 347 YNKNIRAPYLPNTRGPQDSSMFDKYAESTESSSPPIGAAEQQAFF 391
>UniRef50_O13367 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=6; Eukaryota|Rep: CAMP-dependent protein
kinase catalytic subunit - Ustilago maydis (Smut fungus)
Length = 398
Score = 315 bits (774), Expect = 1e-84
Identities = 147/305 (48%), Positives = 202/305 (66%), Gaps = 5/305 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVK---HIVTGK--YYAMKMLEKEKIVRLKQIEHSYYEKKI 110
L+DFE + LGTG FG V LV+ V + Y+A+K+L K +++LKQ+ H E+ I
Sbjct: 74 LSDFEVVETLGTGTFGRVLLVRLKDRDVADRSAYFALKVLAKTDVIKLKQVSHINSERCI 133
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
L ++ PF+V M F+D+ Y ++ ++ GGE+FS+LR+ G F A+FY + ++LA+
Sbjct: 134 LTKVDHPFLVNMIASFQDSKNCYMLMEYVVGGEIFSYLRRAGHFSADVARFYISTIVLAI 193
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKG 230
EYLH+ ++VYRDLKPEN+LID GY KITDFGF K + RTWTLCGTPEYLAPEII G
Sbjct: 194 EYLHSNKVVYRDLKPENLLIDSNGYTKITDFGFAKEVEDRTWTLCGTPEYLAPEIIQCSG 253
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+G +VDWWSLG+LLFEM AG+PPF+ +P+ IYEKI+AG P +D+I +L
Sbjct: 254 HGSAVDWWSLGILLFEMLAGYPPFYDPNPILIYEKILAGNLVFPEEIDPLSRDLISSLLT 313
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEK 350
D +RR G L+ G D KNH WF +DW ++ RI PP P + PGDT+NF ++ +
Sbjct: 314 ADRSRRLGNLRGGANDVKNHPWFHGVDWKALQEGRILPPIVPYLGRPGDTSNFSKYEPAR 373
Query: 351 IKDSP 355
P
Sbjct: 374 PSAMP 378
>UniRef50_Q22DD1 Cluster: Protein kinase domain containing protein;
n=7; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 531
Score = 311 bits (764), Expect = 2e-83
Identities = 161/356 (45%), Positives = 227/356 (63%), Gaps = 15/356 (4%)
Query: 26 AKQEQYSQYLKKLRQDFVESWDDKSESN--AKLNDFERQKVLGTGAFGIVFLVKHIVTGK 83
AKQ Y +K + + ++ K E N LN F + LGTG+FG V L K K
Sbjct: 176 AKQNIQYAYTQKQKNNQNQAQIIKKEQNDTLNLNQFNIKTTLGTGSFGRVKLAKLKGNEK 235
Query: 84 -YYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
+A+KM++K +IV+LKQ+EH EKKIL + PF+V +K F+D +Y+Y + F++GG
Sbjct: 236 DVFALKMMKKIEIVKLKQVEHIKSEKKILSQIKHPFLVELKGTFQDEIYIYMLFEFVSGG 295
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
E+FS LRK G+F + FY ++ LAL+YLH+ +VYRDLKPEN+LID+ G++KI DFG
Sbjct: 296 EIFSRLRKEGRFSNDISLFYITEIYLALQYLHSQNIVYRDLKPENLLIDKEGHVKIADFG 355
Query: 203 FCKLI-RGRTWTLCGTPEYLAPEII--LSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDP 259
F K++ RT+TLCGTPEYLAPEII GYG SVDWW+LGVL+FEM +GHPPF+ DP
Sbjct: 356 FAKIMDSARTYTLCGTPEYLAPEIIQGAKTGYGKSVDWWALGVLIFEMLSGHPPFYDCDP 415
Query: 260 MRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYG---TLKDGVLD-----FKNHK 311
M IY+KIV P FS+ KD++ +L + R G + V+D KNHK
Sbjct: 416 MGIYQKIVNSVINFPEFFSLRAKDLVRKLLNPNIESRLGCQDQILSNVIDQDGNSIKNHK 475
Query: 312 WFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIK-DSPVCLYEEEFADF 366
WF+ ++WD I + +I P+ P+++S D + F+ + E K K ++P ++ FADF
Sbjct: 476 WFKGVNWDKIYHKQIPSPWIPQLKSIDDVSYFEKYPESKDKQENPTKEIQKLFADF 531
>UniRef50_Q20541 Cluster: Cyclic AMP-dependent protein kinase,
catalytic subunit; n=5; Caenorhabditis|Rep: Cyclic
AMP-dependent protein kinase, catalytic subunit -
Caenorhabditis elegans
Length = 371
Score = 309 bits (758), Expect = 9e-83
Identities = 132/302 (43%), Positives = 200/302 (66%), Gaps = 1/302 (0%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+ ER +G G FG V L + +TG +YA+K+L ++V ++Q +H + EK++L L
Sbjct: 60 LSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQTQHVHNEKRVLLQLK 119
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V M KD+ +LY ++ F+ GGEMFS+LR F + A+FY ++++ ALEY+H+
Sbjct: 120 HPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHS 179
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSV 235
+VYRDLKPEN+++ + G+IK+ DFGF K +R RT+T+CGTP+YLAPE + G+ V
Sbjct: 180 LGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTICGTPDYLAPESLARTGHNKGV 239
Query: 236 DWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTR 295
DWW+LG+L++EM G PPF IY+ I+ K + P F++ KD++ +L+VD T+
Sbjct: 240 DWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLAAKDLVKKLLEVDRTQ 299
Query: 296 RYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSP 355
R G +K+G D K+HKWF +++WD L+ R+ PP P + PGDT NFD + EE P
Sbjct: 300 RIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNFDDY-EEDTTGGP 358
Query: 356 VC 357
+C
Sbjct: 359 LC 360
>UniRef50_P21901 Cluster: Spermatozoon-associated protein kinase;
n=1; Aplysia californica|Rep: Spermatozoon-associated
protein kinase - Aplysia californica (California sea
hare)
Length = 351
Score = 309 bits (758), Expect = 9e-83
Identities = 148/349 (42%), Positives = 215/349 (61%), Gaps = 2/349 (0%)
Query: 20 HGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHI 79
H P Q+ +YL+ + F ++ S + ++ + LG+G+FG V L +H
Sbjct: 3 HNQVFPESQKWLKEYLESSLEQFENLFNKNVISTESIRNYTLIRTLGSGSFGRVMLSQHG 62
Query: 80 VTG--KYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLP 137
K YA+K+L KEK+V++KQ+EH+ EK+IL + PFVV FKD LY V+
Sbjct: 63 GDNPQKCYAIKILNKEKVVKMKQVEHTMNEKRILLSIGSPFVVRCLNAFKDTTNLYMVME 122
Query: 138 FIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIK 197
F+ GGE+F LRK G+ E FY AQV +AL+YLH C L+YRDLKPENIL+D GY+K
Sbjct: 123 FVNGGELFHLLRKKGRLPEYWCTFYAAQVTMALQYLHNCSLLYRDLKPENILLDHLGYLK 182
Query: 198 ITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
+TDFGF + ++G TWTLCGTP+YLAPE+IL++ Y LG+L++E++AG PF
Sbjct: 183 VTDFGFDRRVQGHTWTLCGTPQYLAPEMILNRSYASQWTTGGLGILIYELNAGFVPFDHK 242
Query: 258 DPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREID 317
P+++YE IV + PS F L+D++ +++QVD TRR+G L++G LD NH WF++ D
Sbjct: 243 VPLKLYELIVECRLTFPSFFKPTLRDLLTNIIQVDVTRRFGNLRNGALDIINHPWFKDTD 302
Query: 318 WDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
+ IL P+ P ++ FD + EE I S Y +EF++F
Sbjct: 303 FRKILMKAEKAPWVPNLKGQWIHQTFDKWTEESISISKHDKYPDEFSNF 351
>UniRef50_Q6CW38 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome B of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome B of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 455
Score = 305 bits (749), Expect = 1e-81
Identities = 137/297 (46%), Positives = 206/297 (69%), Gaps = 1/297 (0%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF+ + LGTG+FG V LV+ G++YAMK+L+K +V+LKQ+EH+ E+ +L ++
Sbjct: 142 LYDFQILRTLGTGSFGRVHLVRSNHNGRFYAMKVLKKNTVVKLKQVEHTNDERNMLSIVS 201
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ M F+D+ L+ ++ +I GGE+FS LRK +F AKFY A+V LALEYLH+
Sbjct: 202 HPFIIRMWGTFQDSQQLFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 261
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSV 235
++YRDLKPENIL+D+ G+IK+TDFGF K + T+TLCGTP+Y+APE++ +K Y SV
Sbjct: 262 KGIIYRDLKPENILLDKNGHIKLTDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSV 321
Query: 236 DWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTR 295
DWWS GVL++EM AG+ PF+ S+ ++ YE I+ R P F + +D+I ++ D ++
Sbjct: 322 DWWSFGVLIYEMLAGYTPFYDSNTIKTYENILNAPVRFPPFFHSDAQDLISKLITRDLSQ 381
Query: 296 RYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS-PGDTTNFDVFDEEKI 351
R G L++G D KNH WF E+ W+ +L I P+ P I++ GDT+ +D + EE++
Sbjct: 382 RLGNLQNGSEDVKNHPWFSEVVWEKLLCKNIETPYEPPIQAGQGDTSQYDRYPEEEV 438
>UniRef50_P05986 Cluster: cAMP-dependent protein kinase type 3;
n=56; Dikarya|Rep: cAMP-dependent protein kinase type 3
- Saccharomyces cerevisiae (Baker's yeast)
Length = 398
Score = 305 bits (749), Expect = 1e-81
Identities = 137/296 (46%), Positives = 206/296 (69%), Gaps = 1/296 (0%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+DF+ + LGTG+FG V L++ G++YA+K L+K IV+LKQ+EH+ E+++L ++
Sbjct: 85 LSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVS 144
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ M F+D+ ++ V+ +I GGE+FS LRK +F AKFY A+V LALEYLH+
Sbjct: 145 HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 204
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSV 235
+++YRDLKPENIL+D+ G+IKITDFGF K + T+TLCGTP+Y+APE++ +K Y SV
Sbjct: 205 KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSV 264
Query: 236 DWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTR 295
DWWS GVL++EM AG+ PF+ S+ M+ YE I+ + + P F + +D++ ++ D +
Sbjct: 265 DWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSE 324
Query: 296 RYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI-RSPGDTTNFDVFDEEK 350
R G L++G D KNH WF E+ W+ +L I P+ P I + GDT+ FD + EE+
Sbjct: 325 RLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEE 380
>UniRef50_A0CDF0 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_17,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 416
Score = 301 bits (738), Expect = 2e-80
Identities = 152/351 (43%), Positives = 220/351 (62%), Gaps = 9/351 (2%)
Query: 10 INSPRGDLIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGA 69
I++ G+ + + A + Q + Q FV DD E+ KL DF+ +KVLG G+
Sbjct: 29 ISTKEGEQQMNDEFMKAPTATFEQIEETGEQVFV---DDNREAIVKLTDFQFEKVLGRGS 85
Query: 70 FGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDN 129
FG V LV H T K YAMK+L KE I + Q H+ E+ IL + PF+V + Y F+
Sbjct: 86 FGKVMLVTHKETNKLYAMKILRKEMIEKRNQRLHTQNERAILENVKNPFIVQLHYAFQTR 145
Query: 130 VYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENIL 189
LY ++ F+ GGE+F HLR+ +F+E AKFY A++ILA+EYLH +++YRDLKPENIL
Sbjct: 146 TKLYLIMDFLIGGELFFHLRRAFRFQEERAKFYSAELILAIEYLHQRDIIYRDLKPENIL 205
Query: 190 IDRTGYIKITDFGFCKL-IRG--RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFE 246
+D G++KITDFG K+ ++ +T T CGTPEYLAPEI+L G+ VDWWSLG LL+E
Sbjct: 206 LDMEGHLKITDFGLSKINLKDDEKTNTFCGTPEYLAPEILLGGGHNKCVDWWSLGALLYE 265
Query: 247 MSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLD 306
M AG PPF++ D ++++ + FS + I+ +LQ D T+R G +G +
Sbjct: 266 MLAGAPPFYSKDKTQMFKNRLEKPIEMKDWFSSAARSILNGLLQNDPTKRLGV--NGSQE 323
Query: 307 FKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF-DVFDEEKIKDSPV 356
++H++FREIDWD + N +I PPF PK+ D +F D+F +E +D+P+
Sbjct: 324 IRDHEFFREIDWDRLYNKQIQPPFKPKVFGHKDLRHFDDMFTKEPPQDTPI 374
>UniRef50_Q8J0I6 Cluster: CAMP-dependent protein kinase A catalytic
subunit; n=4; Filobasidiella neoformans|Rep:
CAMP-dependent protein kinase A catalytic subunit -
Cryptococcus neoformans var. grubii (Filobasidiella
neoformans var.grubii)
Length = 567
Score = 300 bits (736), Expect = 4e-80
Identities = 132/272 (48%), Positives = 187/272 (68%)
Query: 84 YYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGE 143
++AMK+L K +IVRLKQ+EH E+ IL + PF+V + ++D + +Y +L +I GGE
Sbjct: 253 HFAMKVLRKSEIVRLKQVEHINSERIILERVRHPFIVELHATYQDQINVYMLLFYIPGGE 312
Query: 144 MFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGF 203
+FSHLR+ G+F +FY A ++LA+EYLH+ ++YRDLKPEN+L+DR GY++I DFGF
Sbjct: 313 LFSHLRRAGRFSADVTRFYLASIVLAIEYLHSRNIIYRDLKPENLLLDRHGYLRIADFGF 372
Query: 204 CKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIY 263
K+++ RT+TLCGTPEYLAPEI+LS+G+G +VDWW+LG+L FEM AG+PPFF P+ IY
Sbjct: 373 AKVVQDRTFTLCGTPEYLAPEIVLSQGHGKAVDWWALGILGFEMLAGYPPFFDDHPLGIY 432
Query: 264 EKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILN 323
EKI+ G PSH KD+I +L D ++R G L+ G D H WF +DW S+
Sbjct: 433 EKILRGDIAFPSHIDPFAKDLIRGLLTADRSKRLGNLRGGAKDVMGHPWFAGVDWRSLER 492
Query: 324 SRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSP 355
I P P++ S GD+ NF + + +D P
Sbjct: 493 KEIGAPIVPRVASMGDSQNFQRYPPPRPQDLP 524
>UniRef50_Q33DX4 Cluster: Putative cyclic AMP-dependent protein
kinase catalytic subunit; n=1; Schizophyllum
commune|Rep: Putative cyclic AMP-dependent protein
kinase catalytic subunit - Schizophyllum commune
(Bracket fungus)
Length = 432
Score = 297 bits (728), Expect = 4e-79
Identities = 138/310 (44%), Positives = 193/310 (62%), Gaps = 2/310 (0%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHI--VTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
KL DFE + LGTG F V +V+H + Y+AMK+L K +IVRL+Q+EH E+ IL
Sbjct: 105 KLTDFEVRGTLGTGTFARVLIVRHRGRESNNYFAMKVLRKSEIVRLRQVEHVNAERYILS 164
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
+ PF+V + F+D++ +Y ++ ++ GGE+F+HLR+ +F +FY A +ILAL Y
Sbjct: 165 RIQHPFIVDLFATFQDSLNVYMLMSYVPGGELFTHLRRAQRFTPDVTRFYLATIILALRY 224
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYG 232
LH+ ++YRDLKPEN+L+D GY+++TDFGF K++ RTWTLCGTPEYLAPEII S G+G
Sbjct: 225 LHSFNIIYRDLKPENLLLDSRGYLRLTDFGFAKIVDDRTWTLCGTPEYLAPEIIQSDGHG 284
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+ DWW++GVL +EM G+PPFF P IYEKI+ G P + +I L D
Sbjct: 285 KAADWWAVGVLCYEMLVGYPPFFDESPYGIYEKILDGHIHWPRSMDPLSRSLIRAFLNPD 344
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIK 352
T+R G + G D H WFR +DWD++ I P P S DT +F +
Sbjct: 345 RTKRLGNMIGGPQDVLEHPWFRGVDWDALERREIMAPIIPHTSSGDDTRHFLRLPLPPAE 404
Query: 353 DSPVCLYEEE 362
D P +EE+
Sbjct: 405 DMPGLFHEEQ 414
>UniRef50_O44020 Cluster: PKA protein; n=13; Eukaryota|Rep: PKA
protein - Plasmodium falciparum
Length = 342
Score = 293 bits (720), Expect = 4e-78
Identities = 139/319 (43%), Positives = 198/319 (62%), Gaps = 3/319 (0%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKY--YAMKML 90
Q KK D E ++ K DF LGTG+FG V + G Y A+K
Sbjct: 8 QLNKKKDSDSSEQVLTNKKNKMKYEDFNFICTLGTGSFGRVIFATY-KNGNYPPVAIKRF 66
Query: 91 EKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRK 150
EK KI+R KQ++H + E+KIL +N PF V + FKD+ YLY VL F+ GGE F+ LR+
Sbjct: 67 EKCKIIRQKQVDHVFSERKILNYINHPFCVNLHGSFKDDSYLYLVLEFVIGGEFFTFLRR 126
Query: 151 MGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR 210
+F FY AQ++L EYL + +VYRD KPEN+L+D+ G+IK+TDFGF K++ R
Sbjct: 127 NKRFPNDVGCFYAAQIVLIFEYLQSLNIVYRDFKPENLLLDKDGFIKMTDFGFAKIVETR 186
Query: 211 TWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK 270
T+TLCGTPEY APEI+L+ G+G + DWW+LG+ ++E+ G PPF+A++P+ IY+KI+ G
Sbjct: 187 TYTLCGTPEYTAPEILLNVGHGKAADWWTLGIFIYEILVGCPPFYANEPLLIYQKILEGI 246
Query: 271 YRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPF 330
P K ++ +L D T+RYG LK G + K H WF IDW ++LN + P+
Sbjct: 247 IYFPKFLDNNCKHLMKKLLSHDLTKRYGNLKKGPQNVKEHPWFSNIDWVNLLNKNVEVPY 306
Query: 331 FPKIRSPGDTTNFDVFDEE 349
PK ++ D++NF+ E+
Sbjct: 307 KPKYKNIFDSSNFERVQED 325
>UniRef50_Q695H0 Cluster: CGMP-dependent protein kinase; n=1;
Chlamydomonas reinhardtii|Rep: CGMP-dependent protein
kinase - Chlamydomonas reinhardtii
Length = 1027
Score = 283 bits (694), Expect = 5e-75
Identities = 135/315 (42%), Positives = 202/315 (64%), Gaps = 5/315 (1%)
Query: 47 DDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYY 106
+++ K + E +++GTG FG+V +V++I T + YA+K++ K IV KQIEH
Sbjct: 691 EERKFPRVKFTELEFHRIIGTGQFGLVRVVRNIKTNEVYALKVMHKAPIVESKQIEHVIN 750
Query: 107 EKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+KIL PF V + ++D LY + ++ GGE+F HL G F+E +A FY A
Sbjct: 751 ERKILEEACTHPFCVRLCGAYQDKASLYLLQEWVPGGELFHHLDVEGAFDEPTAMFYAAN 810
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG-RTWTLCGTPEYLAPE 224
V+LALE+LHA +VYRDLKPEN+L+D GYIK+ DFGF K I G +T+T+CGTP+Y APE
Sbjct: 811 VLLALEFLHAKGIVYRDLKPENLLLDTQGYIKMADFGFAKYIGGDKTYTICGTPDYQAPE 870
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPF--FASDPMRIYEKIVAGKYRCPSHFSVELK 282
+I+ +G + D+W+LGVL+FEM G PPF DP + + ++G++ P+ S +
Sbjct: 871 VIMRRGTTKAADYWALGVLIFEMLVGDPPFKSLTGDPWDTFRRTLSGRFYVPNFISDQAA 930
Query: 283 DIIGHVLQVDTTRRYGTLKD-GVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
D+I +LQV+ +R G+ K G + K H+WF IDW ++ ++ PF P++R+P DT+
Sbjct: 931 DLIFKLLQVNPDKRLGSDKRLGAEEIKRHRWFSRIDWRALEQKKLPSPFRPRVRNPLDTS 990
Query: 342 NFDVFDEEKIKDSPV 356
NFD FD ++ PV
Sbjct: 991 NFDNFDNVDLEPPPV 1005
>UniRef50_Q33DX3 Cluster: Putative cyclic AMP-dependent protein
kinase catalytic subunit; n=1; Schizophyllum
commune|Rep: Putative cyclic AMP-dependent protein
kinase catalytic subunit - Schizophyllum commune
(Bracket fungus)
Length = 427
Score = 283 bits (694), Expect = 5e-75
Identities = 136/321 (42%), Positives = 204/321 (63%), Gaps = 9/321 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L DF Q+ LGTG+FG V LV+ ++YA+K+L KEK++R+KQ+EH+ E+ +L +
Sbjct: 97 RLQDFLIQRTLGTGSFGRVLLVRSKHNLRFYAIKVLNKEKVLRMKQVEHTNNERNMLHRV 156
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
N F++ + F+D LY V+ F+ GGE+F+ LR+ +F E AKFY A+V LAL YLH
Sbjct: 157 NHNFIINLWGAFQDGNNLYMVMDFVPGGELFNLLRRSIRFPEPVAKFYAAEVSLALRYLH 216
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMS 234
+ ++YRDLKPENIL++ G+IK+ DFGF K++ +TLCGTP+YLAPEII Y S
Sbjct: 217 SNNIIYRDLKPENILLNADGHIKVADFGFAKIVDTVAYTLCGTPDYLAPEIIWGGRYNKS 276
Query: 235 VDWWSLGVLLFEMSAGHPPFFASD--PMRIYEKIVAGKYRCP---SHFSVELKDIIGHVL 289
VDW++LGVL +EM +G PPF D P +Y KI G P +F++ D+I ++
Sbjct: 277 VDWYALGVLCYEMLSGLPPFHTPDGNPQTLYAKIREGPTSLPWNSPNFTLYSIDLIRRLM 336
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFD-- 347
+ + ++RYG ++ G D H WF E+DW+ + + + PP+ P I GD + FD++
Sbjct: 337 EGEPSKRYGNMRHGAGDVFAHPWFAEVDWEKLEDREVSPPYIPNIGGAGDASAFDIYHED 396
Query: 348 --EEKIKDSPVCLYEEEFADF 366
EE + P+ ++F DF
Sbjct: 397 GMEELFRPPPLDTLADQFPDF 417
>UniRef50_Q2U6J7 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=8; Eurotiomycetidae|Rep: CAMP-dependent
protein kinase catalytic subunit - Aspergillus oryzae
Length = 396
Score = 283 bits (693), Expect = 7e-75
Identities = 139/324 (42%), Positives = 204/324 (62%), Gaps = 13/324 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVK---HI-VTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
++DF K LGTG F V+LV+ I K YA+K+L K +++LKQ+EH E+K L
Sbjct: 73 VDDFALLKTLGTGTFARVWLVRLKDEIRQRDKVYALKILRKADVIKLKQVEHVRNERKTL 132
Query: 112 CGL-NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ PF+ + F D+ LY +L + GGE+FS+LR+ +F E +AKFY A++ L +
Sbjct: 133 SAVAGHPFITTLIASFSDDQSLYMLLDYCPGGEIFSYLRRARRFNENTAKFYAAEITLTI 192
Query: 171 EYLHACE-LVYRDLKPENILIDRTGYIKITDFGFCKLIRGR-TWTLCGTPEYLAPEIILS 228
E+LH E +VYRDLKPENIL+D G+I++ DFGF K + R T+TLCGTPEYLAPE+I +
Sbjct: 193 EFLHDVEGIVYRDLKPENILLDAEGHIRLVDFGFAKKVDNRETYTLCGTPEYLAPEVIHN 252
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
G+G++VDWW+LG+L++E G PPF+ +PMRIYE+IV G+ R P + S ++II +
Sbjct: 253 SGHGLAVDWWALGILIYEFLVGQPPFWDQNPMRIYEQIVEGRIRFPQNMSPAAQNIISLL 312
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDE 348
+ + T R G + G K+H +F +I WD + RI P P++ P DT NF+ + +
Sbjct: 313 CKTNPTERLGYISGGSARVKSHPFFEDIQWDDLFYRRIKGPIIPRVDHPADTGNFEEYPD 372
Query: 349 EKIKDSPVCL------YEEEFADF 366
++ V YE F+DF
Sbjct: 373 PDVRSQNVYTDDLKKKYEALFSDF 396
>UniRef50_Q86ZN6 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=7; Pezizomycotina|Rep: CAMP-dependent protein
kinase catalytic subunit - Magnaporthe grisea (Rice
blast fungus) (Pyricularia grisea)
Length = 408
Score = 279 bits (685), Expect = 6e-74
Identities = 144/366 (39%), Positives = 214/366 (58%), Gaps = 26/366 (7%)
Query: 20 HGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVK-- 77
HG + + + L+ D + +L+DF++ + LGTG F V LV+
Sbjct: 38 HGSVNDGSRTSRNALQGDLKSDAASA--QSQNRKLQLSDFKKVRTLGTGTFARVCLVRPS 95
Query: 78 ----HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN-FPFVVYMKYYFKDNVYL 132
K +A+K+L K ++V+LKQI+H +E+ IL ++ FPF+ M F D+ +L
Sbjct: 96 NPQNETERNKVFALKILRKSEVVKLKQIDHVRHERAILADVSGFPFITNMLASFSDHDFL 155
Query: 133 YYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE--LVYRDLKPENILI 190
Y VL ++ GGE+FS+LRK +F+E A+FY A+++L LEYLH + + YRDLKPEN+L+
Sbjct: 156 YIVLDYVPGGELFSYLRKYRRFDEDMARFYAAEIVLVLEYLHEAQDGVAYRDLKPENLLL 215
Query: 191 DRTGYIKITDFGFCKLIRGR----------TWTLCGTPEYLAPEIILSKGYGMSVDWWSL 240
D G+IK+ DFGF K + GR T+TLCGTPEYLAPE+I +KG+ +VDWW+L
Sbjct: 216 DGQGHIKLVDFGFAKRLGGRRDGDNSGTQETYTLCGTPEYLAPEVIHNKGHTTAVDWWAL 275
Query: 241 GVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH--FSVELKDIIGHVLQVDTTRRYG 298
G+L++E G+PPF+ +P+ IY++IV P S +DII VD +RR G
Sbjct: 276 GILIYEFLTGYPPFWHQNPIEIYKQIVEKPVVFPQDPPISPNAQDIIRQFCTVDRSRRLG 335
Query: 299 TLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCL 358
+ G K H +F +DW++I + + P P IR PGD FD++ EE + P
Sbjct: 336 NISGGAARVKEHPFFEGVDWEAIYSRKFPGPILPPIRYPGDAQCFDIYPEEDVGKDP--- 392
Query: 359 YEEEFA 364
Y +E A
Sbjct: 393 YTDEMA 398
>UniRef50_A6QTK8 Cluster: Serine/threonine-protein kinase PRKX; n=1;
Ajellomyces capsulatus NAm1|Rep:
Serine/threonine-protein kinase PRKX - Ajellomyces
capsulatus NAm1
Length = 412
Score = 279 bits (683), Expect = 1e-73
Identities = 132/309 (42%), Positives = 202/309 (65%), Gaps = 8/309 (2%)
Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIV-TGKY----YAMKMLEKEKIVRLKQIE 102
D S S + DFE + LGTG F V+LV+ + TGK+ YA+K+L K +++LKQ+E
Sbjct: 79 DTSSSELSIGDFELLQTLGTGTFARVWLVRLLKHTGKFKNGAYALKVLHKADVIKLKQVE 138
Query: 103 HSYYEKKILCGL-NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKF 161
H E + L + PF+ + F D++ LY +L + GGE+F+ LR+ +F+ ++A+F
Sbjct: 139 HVRNEIETLNAVAGHPFITTLVATFTDDLSLYMLLEYCPGGEIFTFLRRARRFDVSTAQF 198
Query: 162 YGAQVILALEYLHACE-LVYRDLKPENILIDRTGYIKITDFGFCKLIRGR-TWTLCGTPE 219
Y A+++L LE+LH + YRDLKPENIL+D G++K+ DFGF K I R T+TLCGTPE
Sbjct: 199 YAAEIVLILEFLHDVHGIAYRDLKPENILLDADGHLKLVDFGFAKEIWSRETYTLCGTPE 258
Query: 220 YLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSV 279
YLAPE+I + G+G++VDWW+LGVL++E G PPF+ +PMRIY++IV G R P++
Sbjct: 259 YLAPEVIHNSGHGLAVDWWALGVLIYEFIVGQPPFWDPNPMRIYKQIVDGVLRFPANMPP 318
Query: 280 ELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGD 339
+DI+ + Q + + R G +K G K H +F+ ++WD I + R+ P P++ SP D
Sbjct: 319 AAQDIVSRLCQTNPSERLGHIKGGSARVKQHSFFKGVNWDDIYHRRMKGPIVPRVDSPTD 378
Query: 340 TTNFDVFDE 348
NF+++ +
Sbjct: 379 AGNFEIYPD 387
>UniRef50_P28178 Cluster: Protein kinase 2; n=2; Dictyostelium
discoideum|Rep: Protein kinase 2 - Dictyostelium
discoideum (Slime mold)
Length = 479
Score = 278 bits (682), Expect = 1e-73
Identities = 135/311 (43%), Positives = 197/311 (63%), Gaps = 5/311 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K++ +A +DFE V+G G+FG V VK K +AMK+L K+ I+ KQ+ H+ EK
Sbjct: 143 KNKQSATKDDFELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSEK 202
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
IL ++ PF+V + Y F+ LY VL F+ GGE+F HL++ G+F E K Y A+++
Sbjct: 203 TILQCISHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVS 262
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR--GRTWTLCGTPEYLAPEII 226
AL++LH ++VYRDLKPENIL+D G+I ITDFG K I T+T CGTPEYLAPE++
Sbjct: 263 ALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSKKIETTDGTFTFCGTPEYLAPEVL 322
Query: 227 LSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIG 286
G+G +VDWWSLG LL+EM G PPF++ + +Y+KI+ G+ + P++ S E K ++
Sbjct: 323 NGHGHGCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLE 382
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-V 345
+L + +R GT G + K H WF+ IDW+ + + F PK++S D + D V
Sbjct: 383 GLLTREVDKRLGTKGGG--EVKQHPWFKNIDWEKLDRKEVEVHFKPKVKSGTDISQIDPV 440
Query: 346 FDEEKIKDSPV 356
F +E+ DS V
Sbjct: 441 FTQERPMDSLV 451
>UniRef50_Q24HP6 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 529
Score = 277 bits (680), Expect = 3e-73
Identities = 139/315 (44%), Positives = 210/315 (66%), Gaps = 10/315 (3%)
Query: 48 DKSESNAKL--NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSY 105
++S+ N KL NDF KVLG GAFG V L + T +A+K + KE I+ +QIEH+
Sbjct: 188 NRSDQNTKLSINDFHLIKVLGRGAFGKVMLCQKKDTQDLFAIKSIRKEDIIEREQIEHTK 247
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+KIL +NFPF+V ++Y F+ L++ + F+ GGE+F HL+K KF+E+ A FY +Q
Sbjct: 248 TERKILEQVNFPFLVNLEYAFQTKEKLFFAMKFVRGGELFFHLKKDKKFKESRALFYASQ 307
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI-RGR-TWTLCGTPEYLAP 223
++LALEYLH +++YRDLKPENIL+D+ GY+KITDFG K++ +G+ T +L GTP+YL+P
Sbjct: 308 ILLALEYLHNQDIIYRDLKPENILLDQDGYVKITDFGLAKVLEKGKLTNSLVGTPDYLSP 367
Query: 224 EIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH--FSVEL 281
EII KG+ + D+W+ G+L++EM G PPFF ++ +++ I + P+ S E
Sbjct: 368 EIINQKGHNRTADYWAFGILIYEMVIGIPPFFNNNQNVMFQLISEKDVKFPTSTPLSKEC 427
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
DII +L+ D R G++ +G D K H WF +I++D ILN ++ PF P+++S T
Sbjct: 428 MDIILRLLKKDPNERLGSV-NGTKDIKEHPWFAKINFDEILNRKVPAPFVPQLKS---DT 483
Query: 342 NFDVFDEEKIKDSPV 356
+ FDEE I ++P+
Sbjct: 484 DVSCFDEEFISENPI 498
>UniRef50_Q17941 Cluster: Serine/threonine-protein kinase akt-1;
n=6; Caenorhabditis|Rep: Serine/threonine-protein kinase
akt-1 - Caenorhabditis elegans
Length = 541
Score = 277 bits (680), Expect = 3e-73
Identities = 128/304 (42%), Positives = 193/304 (63%), Gaps = 4/304 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+ DF+ KVLG G FG V L K T K YA+K+L+K+ I+ +++ H+ E ++L
Sbjct: 190 MEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQRCK 249
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F++ YL +V+ F GGE+F+H+RK G F E A+FYGA+++LAL YLH
Sbjct: 250 HPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHR 309
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKGYG 232
C++VYRD+K EN+L+D+ G+IKI DFG CK +T T CGTPEYLAPE++ YG
Sbjct: 310 CDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDDHDYG 369
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
VDWW +GV+++EM G PF++ D +++E I+AG R PS S E + ++ +L D
Sbjct: 370 RCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEARTLLTGLLVKD 429
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
T+R G + L+ +FR +DW++ I PP+ P ++S DT+ FD F + +
Sbjct: 430 PTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYFDNEFTSQPV 489
Query: 352 KDSP 355
+ +P
Sbjct: 490 QLTP 493
>UniRef50_Q4UE84 Cluster: CAMP-dependent protein kinase catalytic
subunit, putative; n=2; Theileria|Rep: CAMP-dependent
protein kinase catalytic subunit, putative - Theileria
annulata
Length = 353
Score = 276 bits (676), Expect = 8e-73
Identities = 121/274 (44%), Positives = 180/274 (65%), Gaps = 3/274 (1%)
Query: 63 KVLGTGAFGIVFLVKHIVTGKYY---AMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFV 119
KVLG G FG VFL + + + A+K L+K ++ KQ++H E K+L +N PF+
Sbjct: 50 KVLGQGGFGKVFLAQKVEENSEFELCAVKRLQKHPLIVQKQVDHIISENKLLASVNHPFI 109
Query: 120 VYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELV 179
V +KDN YLY V+ +++ G+ F++LRK E A FY AQV EYLH ++
Sbjct: 110 VKHLGSYKDNHYLYLVMEYVSSGDFFTYLRKENYLESHDAMFYAAQVTAMFEYLHDNNII 169
Query: 180 YRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWS 239
YRDLKPEN+L+ GY+K+TDFGF K++ RT+TLCGTPEY++PEIIL GYG +VDWW+
Sbjct: 170 YRDLKPENLLLCFDGYLKLTDFGFAKVVEFRTYTLCGTPEYMSPEIILHLGYGKAVDWWT 229
Query: 240 LGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGT 299
LG+L++EM AG+PPF+ S+P +Y+KI+ K + P H+ + K + +L + ++R+G
Sbjct: 230 LGILIYEMLAGYPPFYDSNPQSLYDKILKCKLKFPIHYDEDAKYLTSRLLVTEPSQRFGN 289
Query: 300 LKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
L G+ D K KWF +D+D+++ + PP P+
Sbjct: 290 LHKGIDDIKKCKWFESMDFDALVEKELSPPHIPE 323
>UniRef50_P16911 Cluster: Protein kinase DC1; n=5; Sophophora|Rep:
Protein kinase DC1 - Drosophila melanogaster (Fruit fly)
Length = 376
Score = 275 bits (675), Expect = 1e-72
Identities = 130/272 (47%), Positives = 183/272 (67%), Gaps = 3/272 (1%)
Query: 28 QEQYSQYLKKLRQDFVESWDDKSESN-AKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYA 86
+E Y+ L + ++F E W+ +++S L ++ + VLG G+FG V LV+ YYA
Sbjct: 13 KEDYNVILDNMSREFEERWNHQTQSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYA 72
Query: 87 MKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFS 146
KM+ KE +VRLKQ+ H + EK +L FPF++Y+ K YLY +LP + GGE+FS
Sbjct: 73 AKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFS 132
Query: 147 HLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL 206
+ R++ KF E A+FY AQV LALEY+H L+YRDLKPENIL+D+ GYIKITDFGF K
Sbjct: 133 YHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKR 192
Query: 207 IRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF--FASDPMRIYE 264
+ GRT TLCGTPEYLAPEI+ + Y SVDWW+ G+L++E AG PF D + +Y
Sbjct: 193 VDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYS 252
Query: 265 KIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR 296
KI Y+ PS+F+ +L+ ++ ++QVDT++R
Sbjct: 253 KICICDYKMPSYFTSQLRSLVESLMQVDTSKR 284
>UniRef50_Q4XNV1 Cluster: Rac-beta serine/threonine protein kinase,
putative; n=1; Plasmodium chabaudi|Rep: Rac-beta
serine/threonine protein kinase, putative - Plasmodium
chabaudi
Length = 698
Score = 274 bits (671), Expect = 3e-72
Identities = 130/319 (40%), Positives = 195/319 (61%), Gaps = 4/319 (1%)
Query: 29 EQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
+ + + KK + F+ DK + K F KV+G G++G V LVKH+ + K YAMK
Sbjct: 343 DMHEKSKKKRSRKFIPL-SDKKKRRVKPECFNFLKVIGKGSYGKVLLVKHVQSNKLYAMK 401
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
+L KE I+ Q+EH+ EK IL ++ PF+V M Y F+ + LY++L + GGE+F HL
Sbjct: 402 ILRKENIISKNQLEHTKVEKNILKSVSHPFIVKMYYAFQTSKKLYFILEYCPGGELFFHL 461
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGF---CK 205
K+ KF E A+FY +++I+ L+YLH ++YRDLKPEN+L+D+ G+I++TDFG C
Sbjct: 462 SKLNKFTEEIARFYISEIIITLQYLHKLSIIYRDLKPENVLLDKYGHIRLTDFGLSKKCI 521
Query: 206 LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK 265
+LCGTPEYL+PEII G+G S DWWSLG++L+EM G PF ++E
Sbjct: 522 SDNNSAKSLCGTPEYLSPEIIQQTGHGKSADWWSLGIMLYEMVTGELPFSGESRDVLFEN 581
Query: 266 IVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSR 325
I K + P+ S E+ D++ +LQ + +R G+ + K H +F+ I+WD + + +
Sbjct: 582 IKYKKIKIPNKLSPEVGDLLKKLLQKNPRKRLGSGITDAEEIKKHPFFKNINWDDVCSKK 641
Query: 326 IHPPFFPKIRSPGDTTNFD 344
I PPF P + + D NFD
Sbjct: 642 ISPPFKPVLINTIDLRNFD 660
>UniRef50_P14619 Cluster: cGMP-dependent protein kinase 1, beta
isozyme; n=49; Bilateria|Rep: cGMP-dependent protein
kinase 1, beta isozyme - Homo sapiens (Human)
Length = 686
Score = 273 bits (670), Expect = 4e-72
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 368 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 427
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 428 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 487
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 488 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 547
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 607
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 608 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 667
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 668 PEDNDEPPP 676
>UniRef50_Q6PLK2 Cluster: Protein kinase B-like protein; n=4;
Plasmodium|Rep: Protein kinase B-like protein -
Plasmodium falciparum
Length = 446
Score = 272 bits (667), Expect = 9e-72
Identities = 131/312 (41%), Positives = 194/312 (62%), Gaps = 5/312 (1%)
Query: 36 KKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI 95
K+LR S++ K + F KV+G G++G V LVKH+ K YAMK+L KE I
Sbjct: 93 KRLRNSMSLSYERKKRIRPE--SFNYLKVIGEGSYGKVMLVKHVQNKKLYAMKILRKENI 150
Query: 96 VRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFE 155
+ Q+EH+ E+ IL ++ PF+V M Y F+ LY++L + GGE+F HL K+ +F
Sbjct: 151 LSRNQLEHTKVERNILKCVSHPFIVKMYYAFQTKQKLYFILEYCPGGELFFHLSKLREFS 210
Query: 156 ETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTW 212
E +AKFY +++ILALEYLH ++YRDLKPEN+L+D G+I++TDFG K T
Sbjct: 211 EETAKFYSSEIILALEYLHDLNIIYRDLKPENVLLDELGHIRLTDFGLSKEGITETNLTK 270
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR 272
+LCGTPEYLAPEII KG+G +VDWWSLG++L+EM G PF ++ ++E I K
Sbjct: 271 SLCGTPEYLAPEIIEQKGHGKAVDWWSLGIMLYEMLTGELPFNNTNRNVLFESIKYQKLN 330
Query: 273 CPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
P + S + D++ + + + +R G+ + K H +F+ I+W+ +L ++ PPF P
Sbjct: 331 YPKNLSPKAVDLLTKLFEKNPKKRLGSGGTDAQEIKKHPFFKNINWNDVLYKKVKPPFKP 390
Query: 333 KIRSPGDTTNFD 344
K+ + D NFD
Sbjct: 391 KLFNQLDLQNFD 402
>UniRef50_A0BY36 Cluster: Chromosome undetermined scaffold_136,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_136,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 378
Score = 271 bits (664), Expect = 2e-71
Identities = 139/338 (41%), Positives = 210/338 (62%), Gaps = 7/338 (2%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG 82
++ QE+Y Q +L VE E L DFE KVLG G +G V LV H
Sbjct: 13 HTTLSQEKYQQE-DELDGLQVEQIRLSDEEKVSLKDFEFLKVLGRGGYGKVVLVNHKSQS 71
Query: 83 KYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
K YAMK+L K+ I ++ + E+ IL + PF+V + Y F+ LY+V+ F+ GG
Sbjct: 72 KLYAMKILRKDLIQQMNSRIYMETERNILALVKCPFIVNLYYAFQTKQKLYFVIDFMIGG 131
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
E+F HL+++GK EE+ AKFY A++ILALEYLH+ ++YRDLKPENIL+D+ G++KITDFG
Sbjct: 132 ELFYHLKRIGKMEESWAKFYCAEIILALEYLHSQNIIYRDLKPENILLDQDGHVKITDFG 191
Query: 203 FCKL-IR--GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDP 259
CK+ I+ T T+CGT +Y+APEI L KG+ S DW+SLG+LL+ M G PPF++ +
Sbjct: 192 LCKVDIKEGDFTTTICGTYDYMAPEIYLKKGHNQSADWYSLGILLYVMLQGIPPFYSQNK 251
Query: 260 MRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWD 319
++ + + + S E D+I +L+ + R G+ DG + K+H +F ++W+
Sbjct: 252 RQMIRSRLERQIEIKTPISEEASDLIKQLLKNNPKDRLGS--DGSNEVKSHPFFNGVNWN 309
Query: 320 SILNSRIHPPFFPKIRSPGDTTNFDV-FDEEKIKDSPV 356
+++ ++ PPF PK+ D NFDV F +E ++D+P+
Sbjct: 310 DVMDKKVAPPFKPKLFGDRDLRNFDVTFTQEVVQDTPM 347
>UniRef50_P31751 Cluster: RAC-beta serine/threonine-protein kinase;
n=115; root|Rep: RAC-beta serine/threonine-protein
kinase - Homo sapiens (Human)
Length = 481
Score = 270 bits (662), Expect = 4e-71
Identities = 128/316 (40%), Positives = 194/316 (61%), Gaps = 4/316 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K+ + +NDF+ K+LG G FG V LV+ TG+YYAMK+L KE I+ ++ H+ E
Sbjct: 142 KARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTES 201
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 202 RVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVS 261
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEI 225
ALEYLH+ ++VYRD+K EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE+
Sbjct: 262 ALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEV 321
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ YG +VDWW LGV+++EM G PF+ D R++E I+ + R P S E K ++
Sbjct: 322 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLL 381
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF-D 344
+L+ D +R G + H++F I+W ++ ++ PPF P++ S DT F D
Sbjct: 382 AGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441
Query: 345 VFDEEKIKDSPVCLYE 360
F + I +P Y+
Sbjct: 442 EFTAQSITITPPDRYD 457
>UniRef50_O17474 Cluster: Cyclic GMP-dependent protein kinase; n=1;
Hydra oligactis|Rep: Cyclic GMP-dependent protein kinase
- Hydra oligactis (Hydra)
Length = 742
Score = 269 bits (660), Expect = 7e-71
Identities = 134/305 (43%), Positives = 186/305 (60%), Gaps = 5/305 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVT-GKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
NAKL DF+ LG G FG V LV+ + +A+K L K +V KQ EH + EKKIL
Sbjct: 426 NAKLTDFKPVATLGVGGFGRVELVQDKRNKDRTFALKSLSKHYVVETKQQEHVFNEKKIL 485
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
L+ PF++ + FKD+ Y+Y +L GGE+++ LR FEE + +FY A V+ A E
Sbjct: 486 MSLDSPFIIKLYKSFKDDRYVYLLLEVCLGGELWTILRDRDYFEEAACRFYIACVVEAFE 545
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG--RTWTLCGTPEYLAPEIILSK 229
Y+H ++YRDLKPEN+L+D GYIKI DFGF K I +TWT CGTPEY+ PEIIL+K
Sbjct: 546 YIHKRGIIYRDLKPENLLMDSQGYIKIVDFGFAKKISSGTKTWTFCGTPEYVPPEIILNK 605
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIGH 287
G+ S D+WSLG+L++E+ G+PPF +SDPM Y I+ G + + +++I
Sbjct: 606 GHDSSADYWSLGILIYELMVGNPPFSSSDPMSTYNIILRGIEVLEFSNLVTKNAQNLIKR 665
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFD 347
+ + + R G KDGV D + HKW++ W + N + P PKIR+ D +NFD F
Sbjct: 666 LCKENPMERLGNQKDGVEDIRKHKWYQGFHWSGLRNRTLQAPIIPKIRNITDNSNFDYFS 725
Query: 348 EEKIK 352
K K
Sbjct: 726 PLKEK 730
>UniRef50_P54644 Cluster: RAC family serine/threonine-protein kinase
homolog; n=2; Dictyostelium discoideum|Rep: RAC family
serine/threonine-protein kinase homolog - Dictyostelium
discoideum (Slime mold)
Length = 444
Score = 269 bits (660), Expect = 7e-71
Identities = 131/306 (42%), Positives = 187/306 (61%), Gaps = 9/306 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K + DFE ++G G+FG V V+ TG+ YAMK+L K+ IV ++EH+ E+
Sbjct: 110 KKSEKVGVADFELLNLVGKGSFGKVIQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSER 169
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
IL +N PF+V + Y F+ LY++L ++ GGE+F HL+K KF E ++YGA+++L
Sbjct: 170 NILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVL 229
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LI--RGRTWTLCGTPEYLAPE 224
ALE+LH ++YRDLKPEN+L+ G+I +TDFG CK L+ +T T CGTPEYLAPE
Sbjct: 230 ALEHLHLSGVIYRDLKPENLLLTNEGHICMTDFGLCKEGLLTPTDKTGTFCGTPEYLAPE 289
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ GYG VDWWS G LL+EM G PPF+ D +Y KI+ K P S + + +
Sbjct: 290 VLQGNGYGKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSL 349
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ D +R L D L K H +FR IDW+ + I PPF P ++ DT+ D
Sbjct: 350 LEQLLERDPEKR---LADPNL-IKRHPFFRSIDWEQLFQKNIPPPFIPNVKGSADTSQID 405
Query: 345 -VFDEE 349
VF +E
Sbjct: 406 PVFTDE 411
>UniRef50_Q2U061 Cluster: Ribosomal protein S6 kinase and related
proteins; n=20; Pezizomycotina|Rep: Ribosomal protein S6
kinase and related proteins - Aspergillus oryzae
Length = 681
Score = 268 bits (657), Expect = 2e-70
Identities = 135/315 (42%), Positives = 191/315 (60%), Gaps = 8/315 (2%)
Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107
+ + + KL DFE KV+G G+FG V V TG+ YA+K + K I+ ++ H+ E
Sbjct: 327 ENKQQSLKLEDFELLKVVGKGSFGKVMQVMKKDTGRIYALKTIRKAHIISRSEVTHTLAE 386
Query: 108 KKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
+ +L +N PF+V +K+ F+ LY+VL F+ GGE+F HL++ +F+ A+FY A+++
Sbjct: 387 RSVLAQINNPFIVPLKFSFQSPEKLYFVLAFVNGGELFHHLQREQRFDINRARFYTAELL 446
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPE 224
ALE LH +++YRDLKPENIL+D TG+I + DFG CKL RT T CGTPEYLAPE
Sbjct: 447 CALECLHGFKVIYRDLKPENILLDYTGHIALCDFGLCKLDMKDEDRTNTFCGTPEYLAPE 506
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSV--ELK 282
++L GY SVDWW+LGVLL+EM G PPF+ + +Y KI+ PS V +
Sbjct: 507 LLLGNGYTKSVDWWTLGVLLYEMLTGLPPFYDENTNDMYRKILQEPLTFPSTDIVPAAAR 566
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D++ +L D RR G +G + K+H +F IDW +L + P F P + DT N
Sbjct: 567 DLLTRLLDRDPQRRLGA--NGAAEIKSHHFFANIDWRKLLQRKYEPSFRPNVVDARDTAN 624
Query: 343 FD-VFDEEKIKDSPV 356
FD F E +DS V
Sbjct: 625 FDREFTSEAPQDSYV 639
>UniRef50_Q9P7J8 Cluster: Serine/threonine-protein kinase gad8; n=4;
Dikarya|Rep: Serine/threonine-protein kinase gad8 -
Schizosaccharomyces pombe (Fission yeast)
Length = 569
Score = 268 bits (657), Expect = 2e-70
Identities = 134/305 (43%), Positives = 190/305 (62%), Gaps = 6/305 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++ FE KV+G G+FG V V+ T + YA+K ++K IV +++H+ E+ +L +N
Sbjct: 227 IDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVN 286
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V +K+ F+ LY VL F+ GGE+F HL++ G F+ AKFY A++++ALE LH
Sbjct: 287 NPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHE 346
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGYG 232
++YRDLKPENIL+D TG+I + DFG CKL RT T CGTPEYLAPE++L GY
Sbjct: 347 FNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGYT 406
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
VDWW+LGVLL+EM G PPF+ + +Y KI+ R P + + KD++ +L
Sbjct: 407 KVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTRA 466
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G+ G + KNH +F +IDW + +I PPF P + S DT+NFD F E
Sbjct: 467 PEKRLGS--GGAQEIKNHPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFTSEIP 524
Query: 352 KDSPV 356
DS V
Sbjct: 525 MDSVV 529
>UniRef50_A5DTG0 Cluster: Serine/threonine-protein kinase YPK1; n=4;
Saccharomycetales|Rep: Serine/threonine-protein kinase
YPK1 - Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 788
Score = 267 bits (655), Expect = 3e-70
Identities = 135/312 (43%), Positives = 198/312 (63%), Gaps = 9/312 (2%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
++ + + DF+ KV+G G+FG V V T + YA+K L K+ IV ++ H+ E+
Sbjct: 458 TKKHLSIEDFDLLKVIGKGSFGKVMQVVKKDTRQIYALKTLRKQHIVSRMEVTHTLAERT 517
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
+L ++ PF+V +K+ F+ LY VL FI GGE+F HL++ GKF ++FY A+++ A
Sbjct: 518 VLARISNPFIVPLKFSFQSPEKLYLVLSFINGGELFWHLQREGKFTMDRSRFYIAELLTA 577
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEII 226
LE LH ++YRDLKPENIL+D G+I + DFG CKL +T T CGTPEYLAPE++
Sbjct: 578 LESLHELNVIYRDLKPENILLDYQGHIALCDFGLCKLNMSNDDKTNTFCGTPEYLAPELL 637
Query: 227 LSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHF-SVELKDII 285
+++GY SVDWW+LG LL+EM G PPF+ SD +Y+KI+ R P + +D++
Sbjct: 638 INQGYTRSVDWWTLGTLLYEMLTGLPPFYDSDVPTMYKKILQNPLRFPQFLEGTDAQDLL 697
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+LQ D ++R L D + KNH +F++IDW+ +LN PPF P + + DT+NFD
Sbjct: 698 IKLLQKDPSKR---LND-AQEIKNHPFFKDIDWNKLLNKSYLPPFKPNVENLLDTSNFDQ 753
Query: 346 -FDEEKIKDSPV 356
F EK +DS V
Sbjct: 754 DFTNEKPQDSVV 765
>UniRef50_P12688 Cluster: Serine/threonine-protein kinase YPK1;
n=10; Saccharomycetales|Rep: Serine/threonine-protein
kinase YPK1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 680
Score = 267 bits (655), Expect = 3e-70
Identities = 134/311 (43%), Positives = 196/311 (63%), Gaps = 6/311 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++DF+ KV+G G+FG V V+ T K YA+K + K IV ++ H+ E+ +L ++
Sbjct: 344 IDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVD 403
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V +K+ F+ LY+VL FI GGE+F HL+K G+F+ + A+FY A+++ AL+ LH
Sbjct: 404 CPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHK 463
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGYG 232
++VYRDLKPENIL+D G+I + DFG CKL +T T CGTPEYLAPE++L GY
Sbjct: 464 LDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYT 523
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW+LGVLL+EM G PP++ D ++Y+KI+ P F + KD++ +L D
Sbjct: 524 KAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRD 583
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
TRR G +G + +NH +F ++ W +L PP+ P + + DT+NFD F EK
Sbjct: 584 PTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKP 641
Query: 352 KDSPVCLYEEE 362
DS V Y E
Sbjct: 642 IDSVVDEYLSE 652
>UniRef50_Q2PJ68 Cluster: Putative uncharacterized protein sgk-1;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein sgk-1 - Caenorhabditis elegans
Length = 463
Score = 265 bits (650), Expect = 1e-69
Identities = 129/294 (43%), Positives = 188/294 (63%), Gaps = 7/294 (2%)
Query: 54 AKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG 113
A NDF+ +G G+FG V+ V+H T K YAMK+L KE I + +++H E+ +L
Sbjct: 130 ATANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLIN 189
Query: 114 LNF--PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
NF PF+V + + F++ LY+VL + GGE+FSHL++ F E+ ++FY A++ AL
Sbjct: 190 -NFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALG 248
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRG--RTWTLCGTPEYLAPEIILS 228
YLH ++YRDLKPEN+L+D GY+ +TDFG CK ++G T T CGTPEYLAPEIIL
Sbjct: 249 YLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILK 308
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
K Y +VDWW LG +L+EM G PPF++ D +Y+KI+ R + SV ++I +
Sbjct: 309 KPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGL 368
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
LQ D ++R G D D ++H +F +DWD +LN + PF PK+++ DT+N
Sbjct: 369 LQKDRSKRLGHRND-FRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSN 421
>UniRef50_A0E058 Cluster: Chromosome undetermined scaffold_71, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_71,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 562
Score = 264 bits (647), Expect = 3e-69
Identities = 128/312 (41%), Positives = 195/312 (62%), Gaps = 6/312 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S + + DF+ KVLG GAFG V + + T + +A+K L KE I+ Q+EH+ E+K
Sbjct: 225 SSNMISIEDFDLIKVLGRGAFGKVMMCEKKETKELFAIKSLRKEHIMDKNQLEHTRAERK 284
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
+L ++ PF++ ++Y F+ L++V+ F+ GGE+F HLR +F E++A+FY A ++LA
Sbjct: 285 LLEEIDNPFLISLEYAFQTQEKLFFVMRFMRGGELFKHLRDKRRFPESTAQFYAASILLA 344
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR--GRTWTLCGTPEYLAPEIIL 227
LEYLH ++VYRDLKPENIL+D GYIK+TD+G K ++ T++ GTPEYLAPEII
Sbjct: 345 LEYLHKMQVVYRDLKPENILMDEFGYIKMTDYGLAKFLKPGDFTYSFVGTPEYLAPEIIR 404
Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH--FSVELKDII 285
G+G+ VDWWS G+L++EM G PPFF+ + ++++ IV PS S+++KD+I
Sbjct: 405 QNGHGLGVDWWSFGILIYEMVVGRPPFFSQNQSQLFKSIVESDVVFPSQLTLSIQIKDLI 464
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+L + R G D K H WFR+ + +++ ++ P PK+ D NFD
Sbjct: 465 TQLLTKNPFERLGHNGD-AQSIKEHPWFRDYPFQDLIDKKLQAPIVPKLYDKLDVQNFDQ 523
Query: 345 VFDEEKIKDSPV 356
F E+ +S V
Sbjct: 524 EFTREEAMNSIV 535
>UniRef50_A5K8X1 Cluster: Rac-beta serine/threonine protein kinase,
putative; n=4; Alveolata|Rep: Rac-beta serine/threonine
protein kinase, putative - Plasmodium vivax
Length = 755
Score = 264 bits (646), Expect = 3e-69
Identities = 127/320 (39%), Positives = 196/320 (61%), Gaps = 5/320 (1%)
Query: 29 EQYSQYLK-KLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAM 87
++Y + K + R+ S+ + +S + ++F KV+G G++G V LVKH K YAM
Sbjct: 399 DEYEKQKKGRFRKTLSLSYGRRKKS-LRPDNFTFLKVIGRGSYGKVLLVKHTQNNKLYAM 457
Query: 88 KMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSH 147
K+L KE I+ Q+EH+ E+ +L ++ PF+V + Y F+ LY++L + GGE+F H
Sbjct: 458 KILRKENIISRNQLEHTKIERNVLKCVSHPFIVKLYYAFQTTKKLYFILEYCPGGELFFH 517
Query: 148 LRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK-- 205
L KM + E +A FY A++ILAL+YLH ++YRD+KPEN+L+D G+I++TDFG K
Sbjct: 518 LSKMRELTEEAAIFYTAEIILALQYLHKLNIIYRDVKPENVLLDEMGHIRLTDFGLSKEG 577
Query: 206 -LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYE 264
+LCGTPEYLAPEII G+G +VDWWSLG++L+EM G PF +S ++E
Sbjct: 578 ISDNNSARSLCGTPEYLAPEIIDQCGHGKAVDWWSLGIMLYEMLTGRLPFNSSSRAVLFE 637
Query: 265 KIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNS 324
+I R P S + D++ + + + +R G+ + KNH +F+ ++WD +LN
Sbjct: 638 RIKHETLRYPCFLSPDAVDLLKKLFEKNPKKRLGSGVTDAEEIKNHPFFKNVNWDDVLNK 697
Query: 325 RIHPPFFPKIRSPGDTTNFD 344
++ PPF P + D NFD
Sbjct: 698 KVKPPFKPPLFDQMDVQNFD 717
>UniRef50_Q6CD34 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=2; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome C of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 657
Score = 263 bits (644), Expect = 6e-69
Identities = 129/299 (43%), Positives = 186/299 (62%), Gaps = 5/299 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
KS+S + FE KVLG G FG V +VK T + YA+K + K I+ ++ H+ E+
Sbjct: 324 KSQSQLSMQSFELLKVLGKGTFGKVMMVKKKDTHQIYAIKSIYKHYIISTDEVAHTLAER 383
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V +K+ F+ LY L F+ GGE+F HL++ F+ A+FY A+++
Sbjct: 384 TVLAQIRNPFIVPLKFSFQSPEKLYLGLAFVNGGELFYHLQRERFFDLNRARFYTAELLC 443
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEI 225
ALE LH +VYRDLKPENIL+D G+I + DFG CKL RT T CGTPEY++PEI
Sbjct: 444 ALECLHDYNIVYRDLKPENILLDYMGHIVLCDFGLCKLNMTSDERTNTRCGTPEYMSPEI 503
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+L+KGY SVDWW+LGVLL+EM G PPF++ + ++Y++I+ R P DII
Sbjct: 504 LLNKGYNKSVDWWTLGVLLYEMLTGLPPFYSDNHNKMYQRILNDPLRFPQGMDPTAVDII 563
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+LQ + + R G G + K H +F++IDW+ +L + PF P++ P DT+NFD
Sbjct: 564 TGLLQREPSERLGA--GGAQEIKAHPFFKDIDWNRLLAKKYSAPFKPRVLDPTDTSNFD 620
>UniRef50_Q4SL71 Cluster: Chromosome 17 SCAF14563, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 17
SCAF14563, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 726
Score = 262 bits (643), Expect = 8e-69
Identities = 131/309 (42%), Positives = 187/309 (60%), Gaps = 6/309 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
N L DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK I+
Sbjct: 409 NLNLADFNIINTLGVGGFGRVELVQLKSDENKTFAMKILKKRHIVDTRQQEHIRSEKLIM 468
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 469 QEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFA 528
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILSK 229
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+K
Sbjct: 529 YLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNK 588
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIGH 287
G+ +S D+WSLG+L+FE+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 589 GHDISADYWSLGILMFELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKK 648
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFD 347
+ + + + R G LK+GV D + HKWF +W+ + + PP P + S DT+NFD F
Sbjct: 649 LCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLKKGTLTPPIIPNVTSAIDTSNFDSFP 708
Query: 348 EEKIKDSPV 356
E+ +D P+
Sbjct: 709 EDN-EDPPL 716
>UniRef50_Q5K7C2 Cluster: Protein kinase Sch9, putative; n=4;
Agaricomycotina|Rep: Protein kinase Sch9, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 817
Score = 262 bits (643), Expect = 8e-69
Identities = 138/314 (43%), Positives = 195/314 (62%), Gaps = 8/314 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CG 113
K +DFE K++G G FG VF V+ T + YAMK+L K++IV K++ H+ E+KIL C
Sbjct: 379 KPSDFEFLKLIGRGTFGRVFQVRKKDTRRIYAMKVLSKKEIVAKKEVAHTIGERKILQCS 438
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
L PF+V +K+ F+ + LY+V + GGE+F HL+K G+F E A+FY A+++LALE+L
Sbjct: 439 LECPFLVGLKFSFQTDTELYFVTDYKCGGELFWHLQKEGRFSEDRARFYIAELVLALEHL 498
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIIL-SK 229
H +VYRDLKPENIL+D TG++ + DFG K L + T T CGT EYLAPE++L K
Sbjct: 499 HKYNIVYRDLKPENILLDATGHVALCDFGLSKPDLTDDKLTNTFCGTTEYLAPEVLLDEK 558
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH-FSVELKDIIGHV 288
GYG VD+WSLGVLLFEM G PF+A +Y I GK R P + + K + +
Sbjct: 559 GYGKHVDFWSLGVLLFEMCCGWSPFYAEQTQEMYRLICYGKIRFPKNVIGDDGKQFVKGL 618
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L + R G+ + G ++ K H +F+ IDWD + +I PPF P + S NFD F
Sbjct: 619 LNRNPQNRLGSHR-GAVELKEHPFFKNIDWDLLYKKQITPPFKPIVDSDESVANFDPEFT 677
Query: 348 EEKIKDSPVCLYEE 361
+ D+ + +E+
Sbjct: 678 NSSLLDAGIVPWED 691
>UniRef50_Q96BR1 Cluster: Serine/threonine-protein kinase Sgk3;
n=68; Gnathostomata|Rep: Serine/threonine-protein kinase
Sgk3 - Homo sapiens (Human)
Length = 496
Score = 262 bits (641), Expect = 1e-68
Identities = 135/340 (39%), Positives = 198/340 (58%), Gaps = 9/340 (2%)
Query: 24 SPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGK 83
S + E+ SQ L Q+ + +AK DF+ KV+G G+FG V L K + GK
Sbjct: 129 SEDEDERSSQKLHSTSQNI--NLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGK 186
Query: 84 YYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
+YA+K+L+K+ ++ K+ +H E+ +L + PF+V + Y F+ LY+VL F+ GG
Sbjct: 187 FYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG 246
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
E+F HL++ F E A+FY A++ AL YLH+ ++VYRDLKPENIL+D G++ +TDFG
Sbjct: 247 ELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFG 306
Query: 203 FCK---LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDP 259
CK I T T CGTPEYLAPE+I + Y +VDWW LG +L+EM G PPF+ D
Sbjct: 307 LCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDV 366
Query: 260 MRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWD 319
+Y+ I+ S+ I+ +L+ D R G K+ L+ +NH +F + W
Sbjct: 367 AEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGA-KEDFLEIQNHPFFESLSWA 425
Query: 320 SILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSPVCL 358
++ +I PPF P + P D NFD F EE + S VC+
Sbjct: 426 DLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYS-VCV 464
>UniRef50_Q231C9 Cluster: Protein kinase C terminal domain
containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Protein kinase C terminal domain containing
protein - Tetrahymena thermophila SB210
Length = 358
Score = 261 bits (639), Expect = 2e-68
Identities = 121/300 (40%), Positives = 195/300 (65%), Gaps = 6/300 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K +N+F K++G GA+ V+LV+ + K YA+K+L+K+KI L Q EK
Sbjct: 20 KKSEGISINNFTLLKMIGEGAYAKVYLVRKLDNQKVYALKILKKKKIQELGQQHRVILEK 79
Query: 109 KILCGL-NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
IL + + PF++ + Y F+++ L++ L F GGE+FS L + KF+E +FY AQ++
Sbjct: 80 DILANIESHPFIIKLHYSFQNDTKLFFALDFCPGGELFSILSRKHKFDEEQCRFYAAQIV 139
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK-LIRGRT-WTLCGTPEYLAPEI 225
LA+E+LH ++YRDLKPEN+++D+ GYI+I+DFG K I +T +++CGTPEYLAPEI
Sbjct: 140 LAIEHLHKHNIIYRDLKPENVILDKEGYIRISDFGLSKDNIEDQTAFSVCGTPEYLAPEI 199
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFA-SDPMRIYEKIVAGKYRCPSHFSVELKDI 284
+ + G+G VDWW+LG L++EM G PPF+ ++ +++KI + PS+FS KD+
Sbjct: 200 LNNSGHGKPVDWWALGNLIYEMLTGLPPFYVENNREELFKKIKYTEITIPSYFSKACKDL 259
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ + + +R G+ +G + K+H WF ++DWD +L + + PF PK+++ D +NFD
Sbjct: 260 LTRLFLKNPYQRLGS--NGAEEIKDHPWFTDVDWDKMLQKKYNAPFVPKLKNEIDVSNFD 317
>UniRef50_Q4DL90 Cluster: Rac serine-threonine kinase, putative;
n=2; Trypanosoma cruzi|Rep: Rac serine-threonine kinase,
putative - Trypanosoma cruzi
Length = 705
Score = 260 bits (636), Expect = 5e-68
Identities = 123/295 (41%), Positives = 187/295 (63%), Gaps = 8/295 (2%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
N + DFE V+G G+FG V +H TGK YA+K+L+K+++V+ + H+ EK IL
Sbjct: 345 NVSMRDFELLTVIGLGSFGRVMRARHKATGKIYALKILDKDQVVQHHLVPHTNAEKLILS 404
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
++ PFVV + Y F+ +L VL F+ GGE+F HL++ +F+E A+FY A++ +A+EY
Sbjct: 405 EISHPFVVKLYYAFQTKRHLILVLEFLCGGELFFHLQRCKRFDENRARFYTAEIGMAVEY 464
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSK 229
+H+ ++YRDLKPEN+++DR G++ +TDFG K RT T CGTPEY+APE++
Sbjct: 465 IHSKSVLYRDLKPENLVLDREGHVVLTDFGLAKRDVAEDVRTHTFCGTPEYMAPELVKKS 524
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
G+ +VDWWSLG L+EM G PPF++ + +YE I+ CP+ FS ELK ++G +L
Sbjct: 525 GHTTAVDWWSLGAFLYEMVDGMPPFYSPNVAEMYEMILHKPLVCPARFSPELKSLLGRLL 584
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ D +R + G +F+ H +F +D+D +L I P F P +R D FD
Sbjct: 585 EKDPLKR---MTSGE-EFRAHPFFNGLDFDKLLRREIRPKFVPDVRR-NDLRYFD 634
>UniRef50_A0CMB4 Cluster: Chromosome undetermined scaffold_21, whole
genome shotgun sequence; n=2; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_21, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 333
Score = 259 bits (634), Expect = 9e-68
Identities = 121/299 (40%), Positives = 190/299 (63%), Gaps = 5/299 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
+ S+ +N F+ KV+G G++ V LV+ TGK YA+K L+K+ I + +Q EH E+
Sbjct: 4 EQSSHLTINHFQLIKVIGKGSYAKVLLVRKNDTGKLYAIKALKKKYIQQKRQEEHIMVER 63
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L N F++ + + F++ LY+VL + GGE+F+ L+K K E +FY Q+IL
Sbjct: 64 NVLVSANHQFIIKLAFSFQNERKLYFVLEYCPGGELFNLLQKKKKLTEDQCRFYVCQMIL 123
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTPEYLAPEI 225
A+EYLH ++YRDLKPEN+++D GYI+ITDFG K + +++CGTPEYLAPEI
Sbjct: 124 AIEYLHENNIIYRDLKPENVILDADGYIRITDFGLSKKNVKQDKDAFSVCGTPEYLAPEI 183
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
++ +G+G VDWW+LG ++FEM G PP++++ ++E+I + P + S LK+++
Sbjct: 184 LMKQGHGKPVDWWTLGCIIFEMITGMPPYYSNQRGELFEQIKYQFPKYPQNLSPILKNLL 243
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ Q +R G +G D K+H WF +++WD IL R+ PF PK+ S DT++FD
Sbjct: 244 EGLFQKQPEKRLG--YNGAGDIKSHPWFEKVNWDYILQKRVEAPFKPKLTSEEDTSHFD 300
>UniRef50_Q240P0 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 796
Score = 257 bits (629), Expect = 4e-67
Identities = 129/332 (38%), Positives = 199/332 (59%), Gaps = 8/332 (2%)
Query: 35 LKKLRQD-FVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKE 93
++ +QD ++ S ++ ++DF +KVLG G+FG V LV H+V K YAMK+L K+
Sbjct: 55 IQNQQQDIYMSSEFQRASQKISISDFRLEKVLGKGSFGKVMLVTHLVEQKQYAMKVLLKK 114
Query: 94 KIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGK 153
I +Q H+ E++IL ++ PF+V + Y F+ N LY VL F+ GGE+F HL+K GK
Sbjct: 115 SIKNERQKRHTLTERQILEKIDHPFIVKLHYAFQTNEKLYLVLDFMVGGELFHHLKKSGK 174
Query: 154 FEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWT 213
F E +FY +Q+++ LE+LH +++YRDLKPENIL+D G +K+ DF +
Sbjct: 175 FSEEVTRFYASQIVIGLEHLHQHKIIYRDLKPENILLDSEGNLKLADFE-----NAPAHS 229
Query: 214 LCGTPEYLAPEIILSK-GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR 272
LCGTPEYLAPEII SK G+ +VDWWS G L++EM G PPF++++ ++ I+
Sbjct: 230 LCGTPEYLAPEIITSKVGHDKTVDWWSFGALVYEMLTGSPPFYSNNKKQMLHNIIYKPIP 289
Query: 273 CPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
P + S K ++ +L V+ R G +G D KNH +F I+W+++ +I P
Sbjct: 290 IPKNLSDTAKSLLQQLLVVNPKNRLGYGDNGTSDVKNHPFFATINWEAMKERKIKTPLNI 349
Query: 333 KIRSPGDTTNFDVFD-EEKIKDSPVCLYEEEF 363
+ DT FD + +++ D+PV ++ F
Sbjct: 350 NVTDERDTKYFDPYILKQQAVDTPVSYNQDLF 381
>UniRef50_Q26334 Cluster: Serine/threonine protein kinase; n=2;
Entamoeba histolytica|Rep: Serine/threonine protein
kinase - Entamoeba histolytica
Length = 409
Score = 256 bits (628), Expect = 5e-67
Identities = 127/330 (38%), Positives = 196/330 (59%), Gaps = 9/330 (2%)
Query: 39 RQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRL 98
+++++E +++ + +DFE KV+G G+FG V +VK G+ +AMK+L K+ +
Sbjct: 68 KEEYIELYNE-GKKKVTQDDFELLKVIGRGSFGKVMMVKKKDDGRIFAMKILRKDIVKER 126
Query: 99 KQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETS 158
KQ++H+ EK +L L+ PF+V + Y F+ LY V+ F+ GGE+F HL+ F E
Sbjct: 127 KQVDHTKAEKNVLMQLHHPFIVKLYYAFQTTDKLYMVMDFVNGGELFYHLKNENCFSEER 186
Query: 159 AKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG--RTWTLCG 216
AKFY A++ L ++H+ ++YRDLKPENIL+D TG I ITDFG K + T T CG
Sbjct: 187 AKFYAAEIATVLIHIHSLGIIYRDLKPENILLDNTGNIVITDFGLSKQLAAGEETQTFCG 246
Query: 217 TPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH 276
TP+YLAPEI+ G+G VDWWSLG+L++EM G PPF+ D +Y+KI+ + P +
Sbjct: 247 TPDYLAPEILKGVGHGPGVDWWSLGILIYEMIVGIPPFYDDDVSLMYQKILKSQPHFPRN 306
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
S + K +I +L+ D R G D + WF ID++ + + PP+ P ++S
Sbjct: 307 ISYDAKSVIMGLLEKDPAERLGG-----EDVIHMAWFDSIDFEKLKRKELTPPWIPPVKS 361
Query: 337 PGDTTNFD-VFDEEKIKDSPVCLYEEEFAD 365
+T+ D F +E D+P +E+ D
Sbjct: 362 QTETSQIDEEFVQEAAVDTPPSEEQEQNKD 391
>UniRef50_P11792 Cluster: Serine/threonine-protein kinase SCH9; n=2;
Saccharomyces cerevisiae|Rep: Serine/threonine-protein
kinase SCH9 - Saccharomyces cerevisiae (Baker's yeast)
Length = 824
Score = 256 bits (627), Expect = 7e-67
Identities = 132/293 (45%), Positives = 188/293 (64%), Gaps = 7/293 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL---CGL 114
DFE ++LG G FG V+ VK T + YAMK+L K+ IV+ +I H+ E+ IL
Sbjct: 411 DFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASK 470
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V +K+ F+ LY V +++GGE+F HL+K G+F E AKFY A+++LALE+LH
Sbjct: 471 SSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLH 530
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTLCGTPEYLAPEIILSK-GYG 232
++VYRDLKPENIL+D G I + DFG K ++ RT T CGT EYLAPE++L + GY
Sbjct: 531 DNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYT 590
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH-FSVELKDIIGHVLQV 291
VD+WSLGVL+FEM G PFFA + ++Y+KI GK + P S E + + +L
Sbjct: 591 KMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNR 650
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ R G + DG + + H +F +IDW+++ +I PPF P + S DT+NFD
Sbjct: 651 NPKHRLGAIDDG-RELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFD 702
>UniRef50_Q8INB9 Cluster: RAC serine/threonine-protein kinase; n=8;
Bilateria|Rep: RAC serine/threonine-protein kinase -
Drosophila melanogaster (Fruit fly)
Length = 611
Score = 256 bits (627), Expect = 7e-67
Identities = 124/304 (40%), Positives = 188/304 (61%), Gaps = 4/304 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L +FE KVLG G FG V L + T K YA+K+L+KE I++ ++ H+ E ++L N
Sbjct: 263 LENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTN 322
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ +KY F+ N L +V+ ++ GGE+F HL F E +FYGA++I AL YLH+
Sbjct: 323 HPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHS 382
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++YRDLK EN+L+D+ G+IK+ DFG CK + GRT T CGTPEYLAPE++ YG
Sbjct: 383 QGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYG 442
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW GV+++EM G PF+ D ++ I+ + + P + + E K+++ +L D
Sbjct: 443 QAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKD 502
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G KD V + + H +F I+W ++ +I PPF P++ S DT FD F E +
Sbjct: 503 PKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESV 562
Query: 352 KDSP 355
+ +P
Sbjct: 563 ELTP 566
>UniRef50_Q2UNA7 Cluster: Ribosomal protein S6 kinase and related
proteins; n=5; Pezizomycotina|Rep: Ribosomal protein S6
kinase and related proteins - Aspergillus oryzae
Length = 897
Score = 255 bits (624), Expect = 2e-66
Identities = 129/296 (43%), Positives = 189/296 (63%), Gaps = 9/296 (3%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116
+DF+ K++G G FG V+ VK T + YAMK+L K+ I++ K++ H+ E+ IL
Sbjct: 500 DDFQVLKLIGKGTFGQVYQVKKKDTRRIYAMKVLSKKVIIQKKEVAHTLGERNILVRTAM 559
Query: 117 ---PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+V +K+ F+ LY V +++GGE+F HL+K G+F+E AKFY A++ILAL++L
Sbjct: 560 AASPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFQEARAKFYIAELILALQHL 619
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTPEYLAPEIIL-SK 229
H ++VYRDLKPENIL+D G+I + DFG K + T T CGT EYLAPE++L +
Sbjct: 620 HEHDIVYRDLKPENILLDANGHIALCDFGLSKANLAQNDTTNTFCGTTEYLAPEVLLDEQ 679
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP-SHFSVELKDIIGHV 288
GY VD+WSLGVL+FEM G PF+A D ++Y+ I GK R P S E ++ + +
Sbjct: 680 GYTKMVDFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPRDALSTEGRNFVKGL 739
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
L + R G D + K H +F ++DWD++ ++ PPF PK++S DT+NFD
Sbjct: 740 LNRNPKHRLGAKAD-AKELKEHPFFHDVDWDALSKKQVIPPFKPKLKSDTDTSNFD 794
>UniRef50_Q9HGS0 Cluster: CAMP-dependent protein kinase catalytic
subunit; n=3; Sclerotiniaceae|Rep: CAMP-dependent
protein kinase catalytic subunit - Botrytis cinerea
(Noble rot fungus) (Botryotinia fuckeliana)
Length = 917
Score = 254 bits (623), Expect = 2e-66
Identities = 131/296 (44%), Positives = 191/296 (64%), Gaps = 9/296 (3%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL---CG 113
+DF+ K++G G FG V+ V+ T + YAMK+L+K+ IV+ K++ H+ E+ IL
Sbjct: 512 DDFQILKLIGKGTFGQVYQVRKKDTKRIYAMKVLQKKVIVQKKEVAHTVGERNILVRTAT 571
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+ PF+V +K+ F+ LY V +++GGE+F HL+K G+F+E AKFY A++ILALE+L
Sbjct: 572 ADSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFDEQRAKFYIAELILALEHL 631
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSK- 229
H ++VYRDLKPENIL+D G+I + DFG K L + T T CGT EYLAPE++L +
Sbjct: 632 HKHDIVYRDLKPENILLDANGHIALCDFGLSKANLTKNATTNTFCGTTEYLAPEVLLDEA 691
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP-SHFSVELKDIIGHV 288
GY VD+WSLGVL+FEM G PF+A D ++Y+ I GK R P + E ++ + +
Sbjct: 692 GYTKMVDFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPRDTLTTEGRNFVKGL 751
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
L + R G D + K H +F++IDW ++ I PPF PK++S DT+NFD
Sbjct: 752 LNRNPKHRLGATDDAE-ELKRHPFFQDIDWHALTQKLITPPFKPKLKSETDTSNFD 806
>UniRef50_Q13237 Cluster: cGMP-dependent protein kinase 2; n=23;
Euteleostomi|Rep: cGMP-dependent protein kinase 2 - Homo
sapiens (Human)
Length = 762
Score = 254 bits (622), Expect = 3e-66
Identities = 128/303 (42%), Positives = 182/303 (60%), Gaps = 4/303 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
S++ + E LG G FG V LVK +AMK + K+ IV KQ EH Y EK+IL
Sbjct: 446 SSSPFQNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRIL 505
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
L PF+V + FKDN Y+Y +L GGE++S LR G F+E ++KF A V A +
Sbjct: 506 EELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFD 565
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG--RTWTLCGTPEYLAPEIILSK 229
YLH ++YRDLKPEN+++D GY+K+ DFGF K I +TWT CGTPEY+APE+IL+K
Sbjct: 566 YLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNK 625
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIGH 287
G+ SVD+WSLG+L++E+ G+PPF D M Y I+ G K P + +D+I
Sbjct: 626 GHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRR 685
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFD 347
+ + + T R G LK+G+ D K H+W +W+ + + P +++ P D + FD +
Sbjct: 686 LCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYP 745
Query: 348 EEK 350
EK
Sbjct: 746 PEK 748
>UniRef50_Q7R5X8 Cluster: GLP_81_97826_96747; n=2; Giardia
intestinalis|Rep: GLP_81_97826_96747 - Giardia lamblia
ATCC 50803
Length = 359
Score = 254 bits (621), Expect = 4e-66
Identities = 127/303 (41%), Positives = 178/303 (58%), Gaps = 12/303 (3%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
D K +G+G+FG V L +HI TGKYYA+K + K KI+ L+Q+ H E IL + P
Sbjct: 16 DLRHIKNIGSGSFGRVTLAQHIDTGKYYAVKAMSKRKIIALRQVAHINNECSILRVVRSP 75
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F++ ++D+ +Y +L FI GGE+F HLR+ KF KF+ +++LAL YLH
Sbjct: 76 FIIRQYGTYQDDKNVYIILDFIQGGELFYHLRRYNKFPLQVVKFFAVEILLALGYLHNLG 135
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLIRGR----------TWTLCGTPEYLAPEIIL 227
+ YRDLK EN+L+D TG+IK+ D GF K + + T+++ GTPEYLAPEII
Sbjct: 136 IAYRDLKLENVLVDNTGHIKLADLGFAKRLVEKNADGDTVSQLTFSIVGTPEYLAPEIIR 195
Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGH 287
S G+ MS DWW+ GVL++EM G PPFF +P +KI+ GK S F KD+I
Sbjct: 196 STGHDMSADWWAFGVLIYEMLTGSPPFFDDNPDMTCKKILGGKITFASGFDKAAKDLIIR 255
Query: 288 VLQVDTTRRYG-TLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF-DV 345
+L D TRR G ++ +G D H +F ++W + P PK+ P DT N+ D
Sbjct: 256 LLNPDKTRRLGASINNGTADIMKHAFFSGVNWSWFEKKVVKAPIVPKLTDPADTANYEDY 315
Query: 346 FDE 348
DE
Sbjct: 316 LDE 318
>UniRef50_UPI000049878B Cluster: protein kinase; n=3; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 434
Score = 253 bits (619), Expect = 6e-66
Identities = 124/302 (41%), Positives = 186/302 (61%), Gaps = 8/302 (2%)
Query: 47 DDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYY 106
++K E+ + DF+ +LG GAFG V LVK+ GK YAMK +EK +I+ ++EH
Sbjct: 106 EEKEENKISMEDFDIITLLGKGAFGKVMLVKYKKEGKIYAMKTVEKAQIIDSNEVEHILS 165
Query: 107 EKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRK-MGKFEETSAKFYGAQ 165
EK +L +N PF+V M Y F+ +L ++L + AGGE+FS+L+K E KFY AQ
Sbjct: 166 EKVVLSQINNPFLVNMHYSFQTPTHLVFILDYCAGGELFSYLQKHPAGLPEVDVKFYAAQ 225
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI-RGRTWTLCGTPEYLAPE 224
++LALE++H+ ++YRD+KPENIL ++ GY+++TDFG K +G T T CGTPEYLAPE
Sbjct: 226 IVLALEHMHSTGIIYRDIKPENILFEKDGYLRMTDFGLAKSTKKGTTNTFCGTPEYLAPE 285
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPS--HFSVELK 282
++ Y +DWW LG+L++EM PF A +YE I+ + + PS + E
Sbjct: 286 VVEGLDYNEYIDWWGLGILIYEMLFTQSPFLAETMEELYENILQREPKYPSTKPITEECM 345
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
+ I +L + ++R T D + K H WF ++D + ++ PP+ PKI+S DT+N
Sbjct: 346 NFINSLLIKEPSKRL-TDPDQI---KTHPWFNGFNFDDLYKKKLTPPYVPKIQSQTDTSN 401
Query: 343 FD 344
FD
Sbjct: 402 FD 403
>UniRef50_Q4PH11 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 753
Score = 252 bits (618), Expect = 8e-66
Identities = 133/307 (43%), Positives = 190/307 (61%), Gaps = 8/307 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGLN 115
+DFE K++G G FG VF V+ T + YAMK+L K +I K++ H+ E+KIL L+
Sbjct: 328 HDFEYLKLIGRGTFGRVFQVRKKDTKRIYAMKVLSKREIALKKEVTHTMGERKILEKSLD 387
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V +K+ F+ LY+V + +GGE+F HL++ G+F E A+FY A+++LALE+LH
Sbjct: 388 CPFLVGLKFSFQSATELYFVTDYKSGGELFWHLQREGRFTEERARFYIAELVLALEHLHK 447
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTPEYLAPEIILSK-GY 231
++VYRDLKPENIL+D TG++ + DFG K G T T CGT EYLAPE++L + GY
Sbjct: 448 YDIVYRDLKPENILLDATGHVALCDFGLSKPDLGAGQLTNTFCGTTEYLAPEVLLDESGY 507
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP-SHFSVELKDIIGHVLQ 290
VD+WSLGVLLFEM G PF+A D ++Y I GK + P + K + +L
Sbjct: 508 SKLVDFWSLGVLLFEMCCGWSPFYAEDTQQMYRNICFGKIKFPRGAIGDDGKQFVKGLLN 567
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
+ R G +D D K H +F++ID+D++ ++ PPF P + S NFD F E
Sbjct: 568 RNPRHRLGAQRD-AQDLKEHPFFKDIDFDALSKKQLTPPFKPLVESDESVANFDPEFTET 626
Query: 350 KIKDSPV 356
+KD V
Sbjct: 627 DLKDVAV 633
>UniRef50_Q9UBS0 Cluster: Ribosomal protein S6 kinase beta-2; n=68;
Eumetazoa|Rep: Ribosomal protein S6 kinase beta-2 - Homo
sapiens (Human)
Length = 482
Score = 252 bits (617), Expect = 1e-65
Identities = 127/305 (41%), Positives = 188/305 (61%), Gaps = 8/305 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGL 114
FE +VLG G +G VF V+ + GK YAMK+L K KIVR K H+ E+ IL +
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF+V + Y F+ LY +L ++GGE+F+HL + G F E +A FY A++ LAL +LH
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGY 231
+ ++YRDLKPENI++ G+IK+TDFG CK + G T T CGT EY+APEI++ G+
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 246
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
+VDWWSLG L+++M G PPF A + + +KI+ GK P + + + +D++ L+
Sbjct: 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 306
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEK 350
+ ++R G D + H +FR ++WD +L R+ PPF P ++S D + FD F +
Sbjct: 307 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQT 366
Query: 351 IKDSP 355
DSP
Sbjct: 367 PVDSP 371
>UniRef50_Q54IF2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 641
Score = 252 bits (616), Expect = 1e-65
Identities = 119/298 (39%), Positives = 184/298 (61%), Gaps = 3/298 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S ++DF +++G GAFG V LVK I TG+ YAMK+++K+K + + + H++ E+K
Sbjct: 164 SSKKVTVDDFIFLRMIGRGAFGQVNLVKKIDTGRLYAMKVIKKDKCLNMNAVGHTFTERK 223
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
+L PF+V +KY F+ L VL +I GGE+F H+ + F E +A+FY Q++LA
Sbjct: 224 LLKKYYHPFIVGLKYSFQTQDSLCMVLDYIGGGELFYHISERETFSEETARFYIGQIMLA 283
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEII 226
+ +LH ++YRDLK EN+L+D G I + D G CK + G T+T+CG+PEY+APEII
Sbjct: 284 IGFLHEHGVIYRDLKLENLLMDLDGNICLVDLGLCKEGIQEGHVTYTMCGSPEYVAPEII 343
Query: 227 LSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIG 286
GY SVDWW+LG L +EM AG PPF++ DP + + I++ + P S ++
Sbjct: 344 NGTGYSKSVDWWALGTLFYEMIAGLPPFYSEDPHEMTKLILSSPLKFPPQISKNAASLVS 403
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+L D ++R G+ + V + K H +F+ ++W +LN + PPF P + P D + FD
Sbjct: 404 LLLNRDPSKRLGSGESDVEEIKAHPFFKNVNWSKLLNKEVDPPFKPHLVGPLDLSYFD 461
>UniRef50_Q6C936 Cluster: Yarrowia lipolytica chromosome D of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome D of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 683
Score = 252 bits (616), Expect = 1e-65
Identities = 128/307 (41%), Positives = 191/307 (62%), Gaps = 9/307 (2%)
Query: 46 WDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSY 105
++D + DFE +++G G FG V+ V+ T + YAMK+L K+ +V+ K+I H+
Sbjct: 297 YEDTVRTKMGPEDFEILRLIGKGTFGQVYQVRKKDTRRIYAMKVLSKKVVVQKKEIAHTI 356
Query: 106 YEKKILCGLNF---PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFY 162
E+ IL + PF+V +K+ F+ LY+V +++GGE+F HL++ G+F E AKFY
Sbjct: 357 GERDILVRTSTTQSPFIVGLKFSFQTEADLYFVTDYMSGGELFWHLQREGRFSEQRAKFY 416
Query: 163 GAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPE 219
A++++ALE+LH +VYRDLKPENIL+D G+I + DFG K + +G T T CGT E
Sbjct: 417 IAELVIALEHLHDNNIVYRDLKPENILLDANGHIALCDFGLSKANVTQGDTTSTFCGTTE 476
Query: 220 YLAPEIILSK-GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH-F 277
YLAPE++L + GY VD+WSLGVL+FEM G PF A D ++Y+ I GK + P
Sbjct: 477 YLAPEVLLDESGYTKMVDFWSLGVLIFEMCCGWSPFHADDTQQMYKNIAFGKVKFPKDAL 536
Query: 278 SVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSP 337
S E + + +L + R G +D + + H +F +IDWD ++ +I PPF P + S
Sbjct: 537 SAEGRSFVKGLLNRNPENRLGA-QDDARELRRHPFFHDIDWDQLIQKKIPPPFKPHVASE 595
Query: 338 GDTTNFD 344
DT+NFD
Sbjct: 596 TDTSNFD 602
>UniRef50_A5DV85 Cluster: Serine/threonine-protein kinase SCH9; n=9;
Saccharomycetales|Rep: Serine/threonine-protein kinase
SCH9 - Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 844
Score = 251 bits (615), Expect = 2e-65
Identities = 134/296 (45%), Positives = 185/296 (62%), Gaps = 9/296 (3%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116
+DFE ++LG G FG VF VK T + YAMK+L K+ IV+ K+I H+ E+ IL +
Sbjct: 425 DDFEFLRLLGKGTFGQVFQVKKKDTSRIYAMKILSKKVIVKKKEIAHTIGERNILVRTSA 484
Query: 117 ---PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+V +K+ F+ L+ V +++GGE+F HL+K G+F E AKFY A++ILALE+L
Sbjct: 485 AASPFIVGLKFSFQTPTDLFLVTDYMSGGELFWHLQKDGRFSEERAKFYIAELILALEHL 544
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEIILSK- 229
H ++VYRDLKPENIL+D G+I + DFG K G T T CGT EYLAPEI+L +
Sbjct: 545 HDNDIVYRDLKPENILLDANGHIALCDFGLSKANLNNDGTTNTFCGTTEYLAPEILLDES 604
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH-FSVELKDIIGHV 288
GY VD+WSLGVL+FEM G PF+A + ++Y+ I GK R P S E + + +
Sbjct: 605 GYTKMVDFWSLGVLIFEMCCGWSPFYADNTQQMYKNIAFGKVRFPKEVLSPEGRSFVKGL 664
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
L + R G D + + H +F +IDWD + + I PPF P + S DT+NFD
Sbjct: 665 LNRNPRHRLGATND-ARELRAHPFFADIDWDLLRSKSIPPPFKPHLASETDTSNFD 719
>UniRef50_Q03042 Cluster: cGMP-dependent protein kinase, isozyme 1;
n=28; Eumetazoa|Rep: cGMP-dependent protein kinase,
isozyme 1 - Drosophila melanogaster (Fruit fly)
Length = 768
Score = 251 bits (615), Expect = 2e-65
Identities = 129/298 (43%), Positives = 173/298 (58%), Gaps = 6/298 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVK--HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
KL D E LG G FG V LVK H +A+K L+K IV KQ EH + E+ I+
Sbjct: 453 KLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIML 512
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+ + F+D Y+Y +L GGE+++ LR G FE+ +A+F V+ A EY
Sbjct: 513 SSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEY 572
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILSKG 230
LHA ++YRDLKPEN+++D GY+KI DFGF K I +TWT CGTPEY+APEIIL+KG
Sbjct: 573 LHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKG 632
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIGHV 288
+ +VD+W+LG+L+ E+ G PPF A DPM+ Y I+ G P H S +I +
Sbjct: 633 HDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRL 692
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + R G G+ D K HKWF DWD + + + PPF I P D FD F
Sbjct: 693 CRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDRF 750
>UniRef50_Q5RGL5 Cluster: Novel protein similar to vertebrate
protein kinase, cGMP-dependent, type I; n=3; Danio
rerio|Rep: Novel protein similar to vertebrate protein
kinase, cGMP-dependent, type I - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 570
Score = 251 bits (614), Expect = 2e-65
Identities = 121/288 (42%), Positives = 180/288 (62%), Gaps = 2/288 (0%)
Query: 65 LGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKY 124
LG G FG V LV + KY+AMK + K+ +V KQ H EKKIL + F+V +
Sbjct: 269 LGIGGFGKVELVTTLEHRKYFAMKRISKQHVVAKKQEAHILLEKKILQAIRCDFIVRLHA 328
Query: 125 YFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLK 184
FKD+ Y+Y ++ F GGE+++ L++ G+FEE A F A V+ A YLH ++YRDLK
Sbjct: 329 AFKDSRYVYMIMEFCPGGEIWTKLKEAGRFEEKIAVFITACVVEAYAYLHNKGILYRDLK 388
Query: 185 PENILIDRTGYIKITDFGFCK-LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGV 242
PEN+++D GY+K+ DFGF K L RG +T++ CGTPEY++PEII ++G+ ++ D+WSLGV
Sbjct: 389 PENLMLDSKGYVKLVDFGFAKELSRGEKTYSFCGTPEYISPEIIQNQGHDIAADFWSLGV 448
Query: 243 LLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKD 302
L++E+ G PPF +S+P +IY KI+ G PS+ K II + ++ +R G K+
Sbjct: 449 LIYELLVGSPPFSSSEPQKIYAKILDGVLNFPSYMGEGAKSIISKLCRLRPGQRLGNTKN 508
Query: 303 GVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEK 350
G+ D ++H+WF I+W + ++ P IR NFD F +K
Sbjct: 509 GIKDVRHHRWFNSINWHKLRMGQLEAPTVRLIRKGPCYINFDRFPYDK 556
>UniRef50_A7AWS2 Cluster: cAMP-dependent protein kinase; n=1;
Babesia bovis|Rep: cAMP-dependent protein kinase -
Babesia bovis
Length = 416
Score = 251 bits (614), Expect = 2e-65
Identities = 122/319 (38%), Positives = 200/319 (62%), Gaps = 11/319 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKY-----YAMKMLEKEKIVRLKQIEHSYYEKKI 110
+++F+ ++GTG++ V + + TG +A+K+L K K++ +Q+ H E+ I
Sbjct: 101 ISNFDIGPIVGTGSYATVCIAT-LNTGPKSQRATFALKILHKTKVIAERQVMHLRNERHI 159
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
L + PF+V F+D++ +Y +L +++GGE+FS++ K G T A+FY AQ ILA+
Sbjct: 160 LSTVRHPFIVNYVKSFQDDINVYILLEYVSGGELFSYIYKYGALGHTVARFYTAQAILAI 219
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKG 230
++LH +VYRDLKPEN+L+D+ G+I++ DFGF K ++ +T+T+CGT +YLAPEI L G
Sbjct: 220 DFLHFKGIVYRDLKPENMLLDQDGHIRLVDFGFAKEVKHKTYTVCGTHDYLAPEIFLRCG 279
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+G+ DWWSLGVL++E+ G PPF ASDP Y+ +A R P VE+KD I +L
Sbjct: 280 HGIEADWWSLGVLVYEILTGVPPFHASDPSATYDLALANHIRFPLSVRVEVKDFIRRLLV 339
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF-DEE 349
V+ +R G + +H++F +DW +L+ ++ PP P++ DTTN+ + D+
Sbjct: 340 VNPRKRLGGSNSS--ELYSHRFFAGMDWMKLLSKQLKPPIVPRVSGLSDTTNYMQYPDDW 397
Query: 350 KIKDSPV--CLYEEEFADF 366
+ D+ + +E F+DF
Sbjct: 398 RAHDARITRSQQDEYFSDF 416
>UniRef50_Q245J7 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 397
Score = 250 bits (612), Expect = 4e-65
Identities = 123/313 (39%), Positives = 190/313 (60%), Gaps = 8/313 (2%)
Query: 47 DDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYY 106
+ ++ L+DFE KV+G G+FG VF+V+ GK YAMK L K + + Q +
Sbjct: 60 EQNNQQKVVLSDFEILKVIGEGSFGKVFMVQKKDDGKIYAMKQLRKSNLTKQHQKLKTIE 119
Query: 107 EKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166
EK I+ + PF+V +KY F+ LY+V+ F+ GGEMF H+RK F+E A+FY +++
Sbjct: 120 EKNIMVNMKSPFIVQLKYAFQTTTKLYFVMDFMQGGEMFYHIRKAKYFKEDVARFYVSEL 179
Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAP 223
+LALEYLH+ + +YRDLKPENIL+ G+IKI DFG K +T T+CGTPEYLAP
Sbjct: 180 VLALEYLHSKDTIYRDLKPENILLGADGHIKICDFGLSKQGVKDSDKTKTICGTPEYLAP 239
Query: 224 EIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKD 283
EI+L + +G VDW+SLG +L+E +G PPF++ D ++Y++ + + F + D
Sbjct: 240 EILLGQPHGKEVDWYSLGCVLYEFLSGAPPFYSRDKQQMYQQRINSDIQRKPQFQNDAWD 299
Query: 284 IIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+I +L + R T K+H +F+ +DW+ +LN + PPF K + DT
Sbjct: 300 LIQLLLAKNPKDRLNT----AAQVKSHPFFKTVDWEKLLNKDVRPPFVLKFNNEQDTRYI 355
Query: 344 -DVFDEEKIKDSP 355
+ F ++ ++++P
Sbjct: 356 SNEFVKQAVQNTP 368
>UniRef50_Q9NAH6 Cluster: Putative uncharacterized protein rsks-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein rsks-1 - Caenorhabditis elegans
Length = 580
Score = 249 bits (610), Expect = 8e-65
Identities = 126/306 (41%), Positives = 188/306 (61%), Gaps = 8/306 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCG 113
DF+ KVLG G +G VF V+ G+ +AMK+L+K IVR K H+ E+ IL
Sbjct: 82 DFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAERNILEA 141
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+ PF+ + Y F+ LY +L +++GGE+F HL + G F E AKFY ++++++LE+L
Sbjct: 142 VKSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVSLEHL 201
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRG--RTWTLCGTPEYLAPEIILSKG 230
H ++YRDLKPENIL+D G++K+TDFG CK I G +T T CGT EY+APEI++ G
Sbjct: 202 HQQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPEILMRCG 261
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+G +VDWWSLG L+F+M G PPF A + + +KI+ G+ P++ S E +D+I +L+
Sbjct: 262 HGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPAYLSNEARDLIKKLLK 321
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEE 349
R G + K+H +F+ DW+ + ++ PF P I + DT+ FD F +
Sbjct: 322 RHVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFKPNIENDEDTSLFDARFTKM 381
Query: 350 KIKDSP 355
DSP
Sbjct: 382 TPVDSP 387
>UniRef50_A1CR23 Cluster: CAMP-dependent protein kinase, putative;
n=10; Pezizomycotina|Rep: CAMP-dependent protein kinase,
putative - Aspergillus clavatus
Length = 938
Score = 249 bits (610), Expect = 8e-65
Identities = 128/296 (43%), Positives = 187/296 (63%), Gaps = 9/296 (3%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116
NDF+ K++G G FG V+ V T + YAMK+L K+ I++ K++ H+ E+ IL
Sbjct: 538 NDFQILKLIGKGTFGQVYQVMKKDTHRIYAMKVLSKKVIIQKKEVAHTLGERNILVRTAM 597
Query: 117 ---PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+V +K+ F+ LY V +++GGE+F HL+K G+F+E AKFY A++ILAL++L
Sbjct: 598 AASPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFQEARAKFYIAELILALQHL 657
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIIL-SK 229
H ++VYRDLKPENIL+D G+I + DFG K L + T T CGT EYLAPE++L +
Sbjct: 658 HDHDIVYRDLKPENILLDANGHIALCDFGLSKANLTQNDTTNTFCGTTEYLAPEVLLDEQ 717
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP-SHFSVELKDIIGHV 288
GY VD+WSLGVL+FEM G PF+A D ++Y+ I GK R P S E ++ + +
Sbjct: 718 GYTKMVDFWSLGVLVFEMCCGWSPFYAEDTQQMYKNIAFGKVRFPRDALSTEGRNFVKGL 777
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
L + + R G K + H +F ++DW ++ + PPF PK++S DT+NFD
Sbjct: 778 LNRNPSHRLGA-KGDAKELMAHPFFNDVDWQALARKEVIPPFKPKLKSDTDTSNFD 832
>UniRef50_UPI00006CB772 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 339
Score = 249 bits (609), Expect = 1e-64
Identities = 119/292 (40%), Positives = 186/292 (63%), Gaps = 7/292 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++DF+ + VLG G+F V LVK T K YAMK+L+K+ I R +Q ++ E+ +L +N
Sbjct: 8 IDDFDLKYVLGKGSFAKVVLVKKKDTKKLYAMKILKKDYIQRRRQDQNVMVERNLLVEMN 67
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ +K+ F+ LY+ L + GGE+F+ L K +F E +FY +Q+ILA+E+LH
Sbjct: 68 HPFIIKVKHTFQSEKKLYFCLEYCPGGELFNLLYKKERFNEDQTRFYVSQMILAIEFLHE 127
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKL-IRG--RTWTLCGTPEYLAPEIILSKGYG 232
++YRDLKPEN+LID+ GYI++TDFG K ++G ++ GTPEYLAPEI+ KGYG
Sbjct: 128 KNVIYRDLKPENVLIDKQGYIRVTDFGLSKQNVKGNYEAKSVVGTPEYLAPEILEGKGYG 187
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMR-IYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
+VDWW+LG +++E+ G PPF+ + ++++I K ++ + KD++ +LQ
Sbjct: 188 KTVDWWTLGCIIYELLTGRPPFYKDEGKEDLFQQIQQNKVEIEKNWISDCKDLVLSLLQK 247
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
D R G +G + K+H WF +DWD + N + PPF P I++ DT +
Sbjct: 248 DPKLRLGF--NGAHEIKDHPWFMSLDWDVLKNKKYTPPFVPDIKNE-DTPGY 296
>UniRef50_A0E7B2 Cluster: Chromosome undetermined scaffold_80, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_80,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 428
Score = 249 bits (609), Expect = 1e-64
Identities = 129/338 (38%), Positives = 194/338 (57%), Gaps = 11/338 (3%)
Query: 3 DSEIKRHINSPRGDLIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAK------L 56
D + +N + +++ K E Y + RQ + S ++SE + +
Sbjct: 41 DGQTNEVVNQNQTEMMDDPELQVEKDEFYKLSNENTRQLDIASKTNESEGQGQQTQKVNI 100
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116
+ F KVLG G+FG V LV++ KYYAMK+L+K+ I +Q H+ E+ IL +
Sbjct: 101 DSFRLLKVLGKGSFGKVMLVQYKSNSKYYAMKVLQKKNIKNERQKRHTETERIILATCSS 160
Query: 117 PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHAC 176
F+V ++Y F+ LY V+ ++ GGE+F HLRK+G+F+E AKFY A+++L L+YLH
Sbjct: 161 IFLVRLRYAFQSQYKLYLVVDYMPGGELFYHLRKVGRFKEEVAKFYAAEILLGLQYLHEN 220
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTPEYLAPEIILSK-GYG 232
++YRDLKPENIL+D G+IK+TDFG K++ ++LCGTPEYLAPEI+ +K GY
Sbjct: 221 HIIYRDLKPENILLDENGHIKLTDFGLSKIMMEEDETAFSLCGTPEYLAPEILTTKTGYD 280
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+ DWWS G LL+EM G PP + + + +I+ P + S + ++ +L VD
Sbjct: 281 KTCDWWSFGALLYEMLVGAPPHYKENKKEMIRRILTQPIPYPQYLSENARSLLEQLLVVD 340
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPF 330
+R G DG D H +F ID I+ RI PP+
Sbjct: 341 PKKRLGYENDG-YDIMKHDFFAGIDLAEIIQHRIQPPY 377
>UniRef50_A0BEY5 Cluster: Chromosome undetermined scaffold_103,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_103,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 524
Score = 249 bits (609), Expect = 1e-64
Identities = 126/320 (39%), Positives = 194/320 (60%), Gaps = 8/320 (2%)
Query: 43 VESWDDKSES-NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQI 101
V++ KS S + DF K+LG GAFG V L + T + +A+K L KE I+ I
Sbjct: 182 VQTLYQKSNSPEISIEDFTLIKMLGRGAFGKVMLCEKKDTKEIFAIKSLRKEDIISRDHI 241
Query: 102 EHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKF 161
E+ E+KIL PF+V ++Y F +Y+V+ F+ GGE+++HL+K+ KF E A F
Sbjct: 242 EYLKTERKILEQTQHPFLVSLEYAFITQECVYFVMKFMIGGELYTHLQKINKFNEEFALF 301
Query: 162 YGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK-LIRGR-TWTLCGTPE 219
Y +QV+LALEYLH ++YRDLKPENIL+D GY+ +TD+G K L +G+ T ++ GTPE
Sbjct: 302 YSSQVLLALEYLHKQGIIYRDLKPENILMDEKGYVALTDYGLAKFLSKGQVTQSIVGTPE 361
Query: 220 YLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPS--HF 277
YLAPE+I +G+ + DWW LG+L++EM G PFF+ + +++ IV + + PS H
Sbjct: 362 YLAPEVITQQGHAFTADWWCLGILIYEMLCGKTPFFSENRNQMFRNIVESELKFPSTLHI 421
Query: 278 SVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSP 337
+ E K ++ +L+ R G K + K H WF+ +D+ +++ I P P ++S
Sbjct: 422 TPECKSLLTSLLKKKPNERLGN-KGDAEEIKKHAWFKRMDFQRLISKEIQAPIIPDLQSA 480
Query: 338 GDTTNFD--VFDEEKIKDSP 355
D +NF+ + DE+ + P
Sbjct: 481 TDLSNFNPQILDEKIEEGEP 500
>UniRef50_Q7QUE9 Cluster: GLP_59_15138_16382; n=2; Giardia
intestinalis|Rep: GLP_59_15138_16382 - Giardia lamblia
ATCC 50803
Length = 414
Score = 247 bits (605), Expect = 3e-64
Identities = 122/312 (39%), Positives = 182/312 (58%), Gaps = 6/312 (1%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116
++F KVLG G+FG V L KH K YA+K+L K+ ++ +++EH+ E+ IL LN
Sbjct: 29 DEFTFMKVLGKGSFGTVCLAKHKANNKIYALKVLTKQHVIESREVEHAISERSILASLNH 88
Query: 117 PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHAC 176
PF++ + F+ L VL ++ GGE+F HL+K F+E+ K AQ++LA+EYLH
Sbjct: 89 PFLMRLYGAFQTPTRLIMVLEYVPGGELFFHLKKKVTFDESYVKLVAAQLVLAIEYLHDM 148
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW---TLCGTPEYLAPEIILSKGYGM 233
+V RDLKPENIL+ GYIK+TDFG K T T+ GT EY +PE + + G+G
Sbjct: 149 NIVIRDLKPENILLQANGYIKVTDFGLSKQNLSMTLGAKTMAGTSEYFSPEQVQNCGHGK 208
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
VD W+LG +++E+ G PPF++ D ++ KI+ + + PS+F +LKD++ +L+
Sbjct: 209 GVDMWALGTIIYELLTGSPPFYSDDKRAMFRKIIGEQPKMPSYFKDDLKDLLKGLLEKKP 268
Query: 294 TRRYGTLKD--GVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEK 350
R G K+ G+ + K H WF I+WD + P+ P I D +NFD F E
Sbjct: 269 RSRLGCRKENGGIKELKGHPWFNGINWDKLYRKEYTIPYKPTITDNLDLSNFDKSFTELD 328
Query: 351 IKDSPVCLYEEE 362
S LY+ E
Sbjct: 329 FDFSSEPLYKRE 340
>UniRef50_A0CFD9 Cluster: Chromosome undetermined scaffold_175,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_175,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 383
Score = 247 bits (604), Expect = 4e-64
Identities = 128/332 (38%), Positives = 197/332 (59%), Gaps = 11/332 (3%)
Query: 29 EQYSQYLKKLRQDFVESWDD---KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYY 85
E+ Q LK+ D + D ++ N ND K+LG G+FG V+LVK + K Y
Sbjct: 36 EELIQKLKQQLDDVKKKLGDFEVQNTFNITQNDVWPIKLLGRGSFGKVYLVK--IKDKLY 93
Query: 86 AMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMF 145
AMK ++K+ I++ +Q+E+ YE+ IL + PF++ M + F++ +++ V+ F+ GGE+F
Sbjct: 94 AMKQIKKKLILKKQQLENLLYERFILQKYDHPFIIKMYFVFQEPLFINMVMEFVQGGELF 153
Query: 146 SHLRKMGKFEETSAKFYGAQVILALEYLH-ACELVYRDLKPENILIDRTGYIKITDFGFC 204
HL K KF++ + FY +Q++LALE+LH + YRDLKPEN+L+ R GYIK+ D G
Sbjct: 154 YHLNKRKKFDQKTTAFYASQLVLALEFLHETVRVAYRDLKPENVLLCRDGYIKLADMGLA 213
Query: 205 KLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYE 264
K ++ CGT EYLAPE+I KG+ SVD+W+LG ++FEM GHPPF + +Y
Sbjct: 214 KDNSELNYSFCGTAEYLAPEMIEEKGHNASVDFWTLGCIIFEMLFGHPPFQDENKKNLYI 273
Query: 265 KIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNS 324
KI G+++ P S + +I +LQ R K H++F++ID+D I
Sbjct: 274 KIQTGEFKFPPTASSSAQSLIKGLLQYHPEERL-----SFKQIKQHEFFQDIDFDLIYQK 328
Query: 325 RIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPV 356
++ PPF P + + DT NFD E ++K S +
Sbjct: 329 KLKPPFEPLLTTEKDTRNFDYVLESQMKQSEI 360
>UniRef50_Q22RI5 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 394
Score = 246 bits (602), Expect = 7e-64
Identities = 126/317 (39%), Positives = 182/317 (57%), Gaps = 12/317 (3%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+ L FE K +GTG+FG V+LVK T YAMK+L K++I Q+ + E+ I
Sbjct: 29 QEKINLEHFEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQTKAERYI 88
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
L ++ PFVV + Y F+ LY V+ F GG++F H+ K F E KFY A++ LAL
Sbjct: 89 LENVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFPENKIKFYAAEIFLAL 148
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTPEYLAPEIIL 227
E LH +VYRDLKPENIL+ TG+IK+TDFG K ++ R T++ CGT EY+APEII
Sbjct: 149 EKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSRDEITYSFCGTAEYMAPEIIS 208
Query: 228 SKGYGMSVDWWSL--------GVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSV 279
+G+ ++ DWWS G +L+EM G PPF+ + R+ +K+V +S
Sbjct: 209 KQGHDVASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVIKDKYSK 268
Query: 280 ELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGD 339
E + ++ +L D T+R G +G + +NH +F +DWD L + PP+ PK+ D
Sbjct: 269 ECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFFNNVDWDKFLRLEVQPPYIPKVSDKYD 328
Query: 340 TTNFD-VFDEEKIKDSP 355
N D F + KD+P
Sbjct: 329 LRNIDNNFLKMDSKDTP 345
>UniRef50_P50530 Cluster: Serine/threonine-protein kinase sck1; n=1;
Schizosaccharomyces pombe|Rep: Serine/threonine-protein
kinase sck1 - Schizosaccharomyces pombe (Fission yeast)
Length = 696
Score = 246 bits (602), Expect = 7e-64
Identities = 124/295 (42%), Positives = 181/295 (61%), Gaps = 9/295 (3%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF- 116
DF +++G G FG V+LV+ T + YAMK + K+ IVR K++ H+ E+ IL +
Sbjct: 301 DFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSLD 360
Query: 117 --PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF+V +K+ F+ LY + +++GGE+F HL+ G+F E AKFY A+++LALE+LH
Sbjct: 361 ESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLH 420
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEIIL-SKG 230
+++YRDLKPENIL+D G+I + DFG K T T CGT EYLAPE++L KG
Sbjct: 421 KHDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGTTEYLAPEVLLEDKG 480
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH-FSVELKDIIGHVL 289
Y VD+WSLGVL+FEM G PF+A D ++Y I GK R P S E + + +L
Sbjct: 481 YTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGVLSSEGRSFVRGLL 540
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ R G + D + K H +F +I+WD + ++ PPF P +++ D +NFD
Sbjct: 541 NRNPNHRLGAVAD-TTELKEHPFFADINWDLLSKKKVQPPFKPNVQNDLDVSNFD 594
>UniRef50_Q8MYF1 Cluster: Similar to Dictyostelium discoideum (Slime
mold). Protein kinase 2; n=2; Dictyostelium
discoideum|Rep: Similar to Dictyostelium discoideum
(Slime mold). Protein kinase 2 - Dictyostelium
discoideum (Slime mold)
Length = 456
Score = 245 bits (600), Expect = 1e-63
Identities = 119/299 (39%), Positives = 181/299 (60%), Gaps = 5/299 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K ++ L++F + ++G G FG VF V H+ T K YA+K+++K I+ K + ++ EK
Sbjct: 118 KISNSINLSNFIIKHLVGKGGFGKVFQVVHVDTQKVYALKVIKKNHIIAKKSVVNTLAEK 177
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
IL ++ PF+V + Y F++ LY V+ F+ GG++F HL+K F E +FY A++IL
Sbjct: 178 DILKKISHPFIVNLHYAFQNEKKLYLVMDFVNGGQLFYHLQKEAIFSEDQVRFYMAELIL 237
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEI 225
ALE+LH +V+RDLKPENIL+D G+ +TDFG KL T++ GT EY+APE+
Sbjct: 238 ALEHLHDSNIVHRDLKPENILLDSQGHCILTDFGLAKLEVKTNNETFSFAGTLEYMAPEM 297
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
I G +VDWWS+G+L+++M G PPF + + EKI++ K + P S + +I
Sbjct: 298 IQHATCGKAVDWWSIGILMYDMMIGKPPFEHKNRALMQEKIISEKAKFPKFVSSSARSLI 357
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+L D T+R G +G ++ K H +F+ I W I N I PPF P + D +NFD
Sbjct: 358 NGLLTKDPTKRLGA--NGAIEIKRHPFFKSIQWRKIENKEITPPFVPSTKGIDDISNFD 414
>UniRef50_UPI000065EC1B Cluster: Homolog of Fugu rubripes "Protein
kinase C, alpha type.; n=1; Takifugu rubripes|Rep:
Homolog of Fugu rubripes "Protein kinase C, alpha type.
- Takifugu rubripes
Length = 982
Score = 244 bits (597), Expect = 3e-63
Identities = 120/302 (39%), Positives = 181/302 (59%), Gaps = 7/302 (2%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S + +++DF+ VLG G FG V L + +GK YA+K L+K IV +++ EK+
Sbjct: 651 SNRHLQMDDFKCISVLGRGHFGKVLLAEFKRSGKLYAIKALKKGDIVSRDEVDSLVCEKR 710
Query: 110 ILCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166
I +N PF+V + F+ ++ +V+ + GG++ +H+ F E A+FY + V
Sbjct: 711 IFEVINASRHPFLVNLHGCFQTEEHVCFVMAYSPGGDLMTHIHT-SIFTEKQARFYSSCV 769
Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAP 223
+L LE+LH +++YRDLK +N+L+D G+++I DFG CK G RT T CGTPE+LAP
Sbjct: 770 LLGLEFLHQNKIIYRDLKLDNLLMDADGFVRIADFGLCKEGMGHGDRTSTFCGTPEFLAP 829
Query: 224 EIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKD 283
E++ Y SVDWW LGVL++EM G PF D +++ IV RCP S +
Sbjct: 830 EVLTESNYTRSVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDDVRCPRFLSPQSAS 889
Query: 284 IIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+I +LQ + R G ++ L K+H++F+ DWD++L R+ PPF P IRSP D +NF
Sbjct: 890 LIQQLLQKNPETRLGAGEEDALQVKSHRFFQATDWDALLAKRVKPPFLPVIRSPKDVSNF 949
Query: 344 DV 345
DV
Sbjct: 950 DV 951
>UniRef50_A2BIH5 Cluster: Novel protein similar to vertebrate
protein kinase N2; n=4; Clupeocephala|Rep: Novel protein
similar to vertebrate protein kinase N2 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 970
Score = 244 bits (597), Expect = 3e-63
Identities = 126/323 (39%), Positives = 187/323 (57%), Gaps = 10/323 (3%)
Query: 40 QDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLK 99
Q E D++ + + L DF+ VLG G FG V L ++ +TG+ +A+K L+K IV
Sbjct: 624 QKSTEIRDEEEQFHFSLKDFKCVAVLGRGHFGKVLLAEYTITGEMFAIKALKKGDIVARD 683
Query: 100 QIEHSYYEKKILCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEE 156
++E EK+I +N PF+V + F+ ++ +V+ + AGG++ H+ F E
Sbjct: 684 EVESLMCEKRIFETVNSVRHPFLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHA-DVFSE 742
Query: 157 TSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWT 213
A FY A V+L L++LH ++VYRDLK +N+L+D G++KI DFG CK R RT T
Sbjct: 743 PRATFYAACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYRDRTST 802
Query: 214 LCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRC 273
CGTPE+LAPE++ Y +VDWW LGVL+FEM G PF D +++ IV + R
Sbjct: 803 FCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRY 862
Query: 274 PSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
P S E I+ +L+ + RR G + D K H +FR+IDWD +L ++ PPF P
Sbjct: 863 PRVLSTEAISIMRRLLRRNPERRLGAAERDAEDVKKHLFFRDIDWDGLLAKKVKPPFVPT 922
Query: 334 IRSPGDTTNFDVFDEEKIKDSPV 356
I+ D +N FD+E ++PV
Sbjct: 923 IQCSSDVSN---FDDEFTSEAPV 942
>UniRef50_Q39030 Cluster: Serine/threonine-protein kinase AtPK19;
n=19; Magnoliophyta|Rep: Serine/threonine-protein kinase
AtPK19 - Arabidopsis thaliana (Mouse-ear cress)
Length = 471
Score = 244 bits (597), Expect = 3e-63
Identities = 122/303 (40%), Positives = 178/303 (58%), Gaps = 4/303 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+ DFE KV+G GAFG V+ V+ T + YAMK++ K+KIV E+ E+ IL ++
Sbjct: 137 IEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKID 196
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V +KY F+ LY VL FI GG +F L G F E A+ Y A+++ A+ +LH
Sbjct: 197 HPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHE 256
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILSKGYGM 233
+++RDLKPENIL+D G++ +TDFG K R+ ++CGT EY+APEI+ KG+
Sbjct: 257 KGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDK 316
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
+ DWWS+G+LL+EM G PPF S +I +KIV K + P S E ++ +LQ +
Sbjct: 317 AADWWSVGILLYEMLTGKPPFLGSKG-KIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEP 375
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIK 352
RR G+ G + K HKWF+ I+W + + P F P + NFD + + +
Sbjct: 376 ERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQPSFKPAVSGRQCIANFDKCWTDMSVL 435
Query: 353 DSP 355
DSP
Sbjct: 436 DSP 438
>UniRef50_UPI00006CFFA7 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 535
Score = 244 bits (596), Expect = 4e-63
Identities = 121/303 (39%), Positives = 189/303 (62%), Gaps = 6/303 (1%)
Query: 47 DDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYY 106
+++ + L DF+ KVLG GAFG V LV+ T +++AMK+++K+ I++ + EH+
Sbjct: 204 NNQQRKDVCLEDFQLLKVLGGGAFGKVLLVEDKQTQEWFAMKVIKKQVIIQNGKFEHTKT 263
Query: 107 EKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166
EK IL +NFPF+V + Y F+DN ++++V+ F+ GGE++ +L++ G+F E+ KFY AQ+
Sbjct: 264 EKAILEHVNFPFLVNLVYAFQDNQHIFFVMQFLKGGELYQYLKRDGRFTESRTKFYIAQL 323
Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAP 223
ILAL +LH+ ++YRDLK ENI++D TGYI +TDFG K I + T CGT EYL+P
Sbjct: 324 ILALGHLHSKNIIYRDLKLENIVMDSTGYICLTDFGLAKKIIHQQQIATTFCGTAEYLSP 383
Query: 224 EIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSHFSVEL 281
EI+ G + DWW+LG++ +E+ G+ PF + +++E+I K ++ S E
Sbjct: 384 EILKGDGQDFTADWWALGIICYELLYGNTPFHNKNAHQMFEQIKYAKLEFKNTVAISNEA 443
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
KD I L D T+R G + +G D + H WF +ID++ +L P F P +
Sbjct: 444 KDFIEKCLTKDKTKRLGAI-NGQSDVQAHPWFNDIDFNKLLKKEYSPEFVPVTEGMSWIS 502
Query: 342 NFD 344
NFD
Sbjct: 503 NFD 505
>UniRef50_UPI000049A5C0 Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 439
Score = 244 bits (596), Expect = 4e-63
Identities = 124/338 (36%), Positives = 195/338 (57%), Gaps = 10/338 (2%)
Query: 35 LKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEK 94
LK++ S D + DF+ ++G GAFG V+LVK+ T +AMK+++K++
Sbjct: 97 LKEISDRINVSLDKSEDKYVSSEDFDIISLIGKGAFGKVYLVKNKETQTLFAMKVIQKKQ 156
Query: 95 IVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKF 154
++ +++HS EK IL + PF+V + F+ +V L+YV+ + GGE++S ++K
Sbjct: 157 VIERDEVQHSLEEKNILAKIKHPFLVNLYCSFQTSVNLHYVIDYCPGGELYSLMKKEQTM 216
Query: 155 EETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRT 211
E KFY AQ++LALE+LH ++YRD+KPENILI GYI++TDFG K+ +T
Sbjct: 217 NEKRTKFYAAQLVLALEHLHNQGIIYRDVKPENILICADGYIRLTDFGLSKMGISDNSKT 276
Query: 212 WTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
T CGTPEYLAPE+I + Y ++DWW LGVL++EM G PF+ + R+Y I+ +
Sbjct: 277 ATFCGTPEYLAPEVIQNVAYTNAIDWWGLGVLIYEMLYGTVPFYDENIQRLYHNILYNQV 336
Query: 272 RCPSH--FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
H S+E +DII +L+ + R D + K+H WF ++ WD++ ++ P
Sbjct: 337 TFLEHTEISLECRDIISQLLKKNPIERLHE-TDAI---KSHPWFHDLHWDNLFAKKVLPD 392
Query: 330 FFPKIRSPGDTTNF-DVFDEEKIKDSPVCLYEEEFADF 366
+ P++ SP D F E+ + + E F DF
Sbjct: 393 YLPQLSSPTDLRYFYKEITEQSLSLGGEVVSNELFTDF 430
>UniRef50_Q4SLK1 Cluster: Chromosome 15 SCAF14556, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 15
SCAF14556, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 395
Score = 243 bits (595), Expect = 5e-63
Identities = 111/193 (57%), Positives = 146/193 (75%), Gaps = 4/193 (2%)
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGM 233
HAC + R + ++ + +G+ ++TDFGF K ++GRTWTLCGTPEYLAPEIILSKGY
Sbjct: 207 HACGRLLRPVPVAHVWL--SGF-QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNK 263
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
+VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+GK R PSHFS +LKD++ ++LQVD
Sbjct: 264 AVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDL 323
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKD 353
T+RYG LK+GV D K HKWF DW +I R PF PK R PGDT+NFD ++EE+I+
Sbjct: 324 TKRYGNLKNGVNDIKGHKWFATTDWIAIY-ERKATPFIPKCRGPGDTSNFDDYEEEEIRV 382
Query: 354 SPVCLYEEEFADF 366
S +EFA+F
Sbjct: 383 SLTEKCAKEFAEF 395
Score = 194 bits (474), Expect = 2e-48
Identities = 85/149 (57%), Positives = 119/149 (79%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+S L+DF+R K LGTG+FG V LVKH T +Y+AMK+L+K+K+V+LKQIEH+ EK+I
Sbjct: 54 QSTTCLDDFDRLKTLGTGSFGRVMLVKHKGTEQYFAMKILDKQKVVKLKQIEHTLNEKRI 113
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
L ++FPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G+F E A+FY AQ++L
Sbjct: 114 LQAVSFPFLVKLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTF 173
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKIT 199
EYLH+ +L+YRDLKPEN+LID GYI+++
Sbjct: 174 EYLHSLDLIYRDLKPENLLIDHHGYIQVS 202
>UniRef50_Q10364 Cluster: Serine/threonine-protein kinase sck2; n=1;
Schizosaccharomyces pombe|Rep: Serine/threonine-protein
kinase sck2 - Schizosaccharomyces pombe (Fission yeast)
Length = 646
Score = 243 bits (595), Expect = 5e-63
Identities = 132/297 (44%), Positives = 184/297 (61%), Gaps = 9/297 (3%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC---G 113
+DF K++G G FG V+LV+ T + YAMK+L K+ IVR K++ H+ E+ IL
Sbjct: 264 DDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSA 323
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+ PF+V +++ F+ LY V ++AGGE+F HL+K +F E AKFY A+++LAL+ L
Sbjct: 324 ADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQAL 383
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEIILSK- 229
H +VYRDLKPENIL+D G+I + DFG K + T T CGT +YLAPE+IL +
Sbjct: 384 HKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLAPEVILDEA 443
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP-SHFSVELKDIIGHV 288
GY M VD+WSLGVLL+EM+ G PF+A + ++Y+ IV GK R P SVE +D+I +
Sbjct: 444 GYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLLSVEARDLIKLL 503
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
L + R G D V + H +F IDW + I PPF P + D +NFDV
Sbjct: 504 LNRNPKHRLGAHGD-VEEVMKHPFFDGIDWKKLAAKEISPPFKPIVEGEIDVSNFDV 559
>UniRef50_Q8MQE4 Cluster: Putative uncharacterized protein; n=5;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 617
Score = 242 bits (592), Expect = 1e-62
Identities = 122/300 (40%), Positives = 183/300 (61%), Gaps = 7/300 (2%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E++ +L D +R LG G FG V LV+ + + YA+K++ K IV KQ H E++I
Sbjct: 302 EADVELEDLQRVSTLGMGGFGRVELVRS-ASSRTYALKIMNKAHIVETKQESHVVSERRI 360
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
L + ++V M ++D+ +Y ++ GGE+++ LRK G+F+ +FY A + AL
Sbjct: 361 LMQCDNDYIVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEAL 420
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR--GRTWTLCGTPEYLAPEIILS 228
EYLH +VYRDLKPEN+L+DR G+ K+ DFGF K ++ GRTWT CGT EY+APEI+L+
Sbjct: 421 EYLHRKNIVYRDLKPENMLLDRNGWPKLVDFGFAKKLKNGGRTWTFCGTAEYVAPEIVLN 480
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +SVD W+LG+ + E+ G PPF ++DPM Y I+ G K+ P + E D++
Sbjct: 481 KGHDLSVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWPRFVTKEAIDMML 540
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + T R G G + ++H WF D+ RI PPF P + + DT+NFD F
Sbjct: 541 SLCKYEPTERLGFGDIG--EIRHHIWFDNFDFVGFRAHRIRPPFIPSVANDIDTSNFDTF 598
>UniRef50_A0DUX2 Cluster: Chromosome undetermined scaffold_65, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_65,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 371
Score = 242 bits (592), Expect = 1e-62
Identities = 125/327 (38%), Positives = 193/327 (59%), Gaps = 8/327 (2%)
Query: 44 ESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEH 103
ES D K + N L+DFE KV+G G+FG V LVK + +A+K+L K+ + + KQ +
Sbjct: 43 ESADSKQKLN--LDDFELIKVIGRGSFGKVLLVKKRDDQQLFAVKILRKKMLSKKKQQDQ 100
Query: 104 SYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYG 163
+ E+KI+ +N PF+V + Y F+ + LY V+ F+ GGE+F HLRK KF E +FY
Sbjct: 101 AIKERKIMSLINSPFMVKLHYAFQSHSRLYMVMDFMQGGELFLHLRKRFKFPEDWVQFYA 160
Query: 164 AQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEY 220
A++++A++ LH ++YRDLKPENIL+D+ G+I +TDFG KL T++ CGTPEY
Sbjct: 161 AELLVAIDLLHQSNIIYRDLKPENILLDKNGHIVLTDFGLSKLGFEKNEMTYSFCGTPEY 220
Query: 221 LAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVE 280
+APEI+ +G+ VD++S G +++EM G PPF++ D + + S FS
Sbjct: 221 VAPEILYQRGHTFVVDFYSYGAMIYEMLCGSPPFYSKDKREMLKNRCEKPLEMKSCFSFY 280
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
++ +L D R G+ +G+ + K H +F IDW + ++ PP PKI+ D
Sbjct: 281 AASLLKGLLTKDPGLRLGS--NGIQEIKKHNFFNGIDWKLVEQRKLQPPIIPKIQHVQDL 338
Query: 341 TNF-DVFDEEKIKDSPVCLYEEEFADF 366
NF F ++ I ++P + E F F
Sbjct: 339 QNFAPAFLQQPIMETPESVSNEYFEGF 365
>UniRef50_Q4RR21 Cluster: Chromosome 14 SCAF15003, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
SCAF15003, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 621
Score = 241 bits (591), Expect = 2e-62
Identities = 118/279 (42%), Positives = 177/279 (63%), Gaps = 11/279 (3%)
Query: 65 LGTGAFGIVFLV------KHIVT---GKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
LG G FG V LV + T G YYAMK + K+ IV +Q EH +EKKIL +
Sbjct: 317 LGVGGFGRVELVGVMAYLPQMTTVNHGMYYAMKRVSKKHIVAKRQEEHMLFEKKILKAIQ 376
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
F+V + FKD Y+Y ++ F GGE+++ L+++G+F+E A F A V+ A YLH
Sbjct: 377 CDFIVRLHATFKDTRYVYMIMEFCGGGEIWTKLKEVGRFDEPMAVFCAACVVEAFAYLHK 436
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK-LIRG-RTWTLCGTPEYLAPEIILSKGYGM 233
++YRDLKPEN+++D GY+K+ DFGF K ++R +T++ GTPEY+APEII ++G+
Sbjct: 437 KSIMYRDLKPENLMLDAKGYVKLVDFGFAKEMVRAEKTYSFVGTPEYMAPEIIKNQGHDF 496
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
+VD+WSLG+L+FE+ AG PPF +S+P +IY KI+ G + P + S K II + +
Sbjct: 497 AVDFWSLGILIFELLAGSPPFSSSEPQKIYAKILDGVLKYPPYLSEASKSIISKLCRPRP 556
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
+R G K+G+ D ++H+WF I+W + S++ P P
Sbjct: 557 GQRLGNTKNGIKDVRHHRWFSSINWHKLRMSQLDAPTGP 595
>UniRef50_A7TPV4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 665
Score = 241 bits (591), Expect = 2e-62
Identities = 123/293 (41%), Positives = 184/293 (62%), Gaps = 7/293 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLN- 115
DF ++LG G FG V+ V+ T YAMK++ K +++ K+++H+ E+ IL N
Sbjct: 261 DFNILRMLGKGTFGRVYQVEKKDTKTLYAMKVISKRNVIKRKEVKHTLNERNILVHNANK 320
Query: 116 -FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
F+V +K+ F+ LY V F++GGE+F HL++ G+F E AKFY AQ+++ALE+LH
Sbjct: 321 LCSFIVKLKFSFQTAEDLYLVTDFMSGGELFLHLQREGRFPEYRAKFYCAQLVMALEFLH 380
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTLCGTPEYLAPEIIL-SKGYG 232
+++YRDLKPENIL+D G I + DFG KL + GRT T CGT EYLAPE++L + GY
Sbjct: 381 DNDIIYRDLKPENILLDAKGNIALCDFGLSKLNLEGRTNTFCGTTEYLAPELLLDATGYT 440
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP-SHFSVELKDIIGHVLQV 291
VD+WSLGVL+FEM G PFFA ++Y+KI K + P + S + I ++
Sbjct: 441 KMVDFWSLGVLMFEMCCGWSPFFAPTNQQMYQKIAYSKIKFPVNSLSKGCRLFIKGLMNR 500
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ R G + D + + H++FR+ DW++++ + PPF P + S DT+ FD
Sbjct: 501 NPLHRLGAIND-ARELRAHEFFRDTDWEALMKKEVTPPFKPHLSSDRDTSYFD 552
>UniRef50_Q22HC2 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 436
Score = 241 bits (590), Expect = 2e-62
Identities = 122/309 (39%), Positives = 184/309 (59%), Gaps = 8/309 (2%)
Query: 64 VLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMK 123
VLG G+FG V LV+ T + YAMK+L+K+ I Q ++ E+ IL +N PF+V +
Sbjct: 78 VLGKGSFGKVVLVEKKDTKELYAMKILKKDYIQYTNQKFNTQQERDILVKMNSPFIVKLH 137
Query: 124 YYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDL 183
Y F+ LY V+ F+ GGE+F HLR+ F E A +Y A++IL +E LH+ ++YRDL
Sbjct: 138 YAFQTADKLYIVMDFMIGGELFYHLRRSPIFTEEKAAYYSAEIILGIEALHSNNIIYRDL 197
Query: 184 KPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSL 240
KPENILID G++++ DFG K RT +LCGTPEYLAPEI+L+ G+ VDWWSL
Sbjct: 198 KPENILIDHKGHLRLADFGLSKKGVKDHERTNSLCGTPEYLAPEILLNNGHTKMVDWWSL 257
Query: 241 GVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTL 300
G +++EM G PPF+ + ++++ FS K ++ +L ++ R G
Sbjct: 258 GAIIYEMLTGAPPFYNKNQKQMFKDRFLKPIEMKEWFSPAAKSLLSGLLNINPELRLGF- 316
Query: 301 KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSPVC-- 357
G+ + K H+++ I+WD + I PP+ PK+ S D ++F F E +KD+P C
Sbjct: 317 -KGIQEIKEHEFYASINWDKLYKKEIPPPYKPKLSSKYDLSHFSKQFTTETVKDTPYCGK 375
Query: 358 LYEEEFADF 366
++ + DF
Sbjct: 376 TIKDSYNDF 384
>UniRef50_O76360 Cluster: Egg laying defective protein 4, isoform a;
n=5; Caenorhabditis elegans|Rep: Egg laying defective
protein 4, isoform a - Caenorhabditis elegans
Length = 780
Score = 241 bits (590), Expect = 2e-62
Identities = 126/308 (40%), Positives = 184/308 (59%), Gaps = 12/308 (3%)
Query: 47 DDKSESNAK--LNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQI 101
DD E A+ L + +R LG G FG V LV V G K +A+K L+K+ IV +Q
Sbjct: 455 DDFREEFAQVTLKNVKRLATLGVGGFGRVELV--CVNGDKAKTFALKALKKKHIVDTRQQ 512
Query: 102 EHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKF 161
EH + E+ I+ + ++V + F+D ++Y +L GGE+++ LR G F++ +A+F
Sbjct: 513 EHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARF 572
Query: 162 YGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGR-TWTLCGTPE 219
Y A V+ LEYLH +VYRDLKPEN L+ TGY+K+ DFGF KL GR TWT CGTPE
Sbjct: 573 YVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPE 632
Query: 220 YLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPS-H 276
Y++PEIIL+KG+ + D+W+LG+ + E+ G PPF ASDPM+ Y I+ G P+
Sbjct: 633 YVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRR 692
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
++ + + + R G+ GV D + H+WF DW+ + + + PP PK+ +
Sbjct: 693 IGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSN 752
Query: 337 PGDTTNFD 344
P D TNFD
Sbjct: 753 PADVTNFD 760
>UniRef50_UPI0000DB6E55 Cluster: PREDICTED: similar to
cGMP-dependent protein kinase 21D CG3324-PA; n=2;
Apocrita|Rep: PREDICTED: similar to cGMP-dependent
protein kinase 21D CG3324-PA - Apis mellifera
Length = 723
Score = 241 bits (589), Expect = 3e-62
Identities = 120/335 (35%), Positives = 202/335 (60%), Gaps = 6/335 (1%)
Query: 21 GGYSPAKQEQY-SQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVK-H 78
GG + + + ++Y K+ R + W + SN L D + + LG G FG V LV
Sbjct: 376 GGLDEIRNKDWLAEYEKQKRSLTFKKWSHEY-SNVTLADLDTKGTLGVGGFGRVDLVTLK 434
Query: 79 IVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPF 138
+ K +A+K L+K+ +V +Q EH EK I+ + PF+ + +KD Y+Y+++
Sbjct: 435 SDSEKSFALKKLKKKVMVEQQQQEHVLNEKHIMQACDSPFICKLYQTYKDRKYVYFLMEV 494
Query: 139 IAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKI 198
GG++++ L++ F++ +A+F V+ AL++LH+ +VYRDLKPEN+++D GY+K+
Sbjct: 495 CLGGDVWTTLQRRRFFDDATAQFMVGCVVEALDHLHSMNIVYRDLKPENLMLDIRGYLKL 554
Query: 199 TDFGFCKLI-RGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
DFGF K I +TWT GTPEY+APEIIL++G+ +VD+W+LG+L+ E+ G PPF S
Sbjct: 555 VDFGFSKKIGPSKTWTFAGTPEYVAPEIILNRGHDRAVDYWALGILIHELLIGKPPFRGS 614
Query: 258 DPMRIYEKIVAG--KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFRE 315
D M IY KIV G P+ + ++I +L+++ + R G ++G+ D ++HKWF
Sbjct: 615 DHMTIYNKIVKGIEVVGIPNTINKNANNLIKKLLRLNPSERLGYQRNGIQDIRDHKWFHG 674
Query: 316 IDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEK 350
+W+++ + P P ++S DT NF+ + ++
Sbjct: 675 FNWNALQKLTLPAPIVPTVQSRIDTRNFERYPPDR 709
>UniRef50_P23443 Cluster: Ribosomal protein S6 kinase beta-1 (EC
2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1)
(70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase
alpha) (p70(S6K)-alpha); n=19; Bilateria|Rep: Ribosomal
protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal
protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal
protein S6 kinase 1) (p70 S6 kinase alpha)
(p70(S6K)-alpha) - Homo sapiens (Human)
Length = 525
Score = 240 bits (587), Expect = 5e-62
Identities = 130/362 (35%), Positives = 206/362 (56%), Gaps = 12/362 (3%)
Query: 2 ADSEIKRHINSPRGDLIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFER 61
A SE + + + HGG P E ++ +K + E+ ++ + FE
Sbjct: 38 AGSEDELEEGGQLNESMDHGGVGP--YELGMEHCEKF--EISETSVNRGPEKIRPECFEL 93
Query: 62 QKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGLNFP 117
+VLG G +G VF V+ + TGK +AMK+L+K IVR K H+ E+ IL + P
Sbjct: 94 LRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHP 153
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F+V + Y F+ LY +L +++GGE+F L + G F E +A FY A++ +AL +LH
Sbjct: 154 FIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKG 213
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGYGMS 234
++YRDLKPENI+++ G++K+TDFG CK + G T T CGT EY+APEI++ G+ +
Sbjct: 214 IIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRA 273
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTT 294
VDWWSLG L+++M G PPF + + +KI+ K P + + E +D++ +L+ +
Sbjct: 274 VDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAA 333
Query: 295 RRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKD 353
R G + + H +FR I+W+ +L ++ PPF P ++S D + FD F + D
Sbjct: 334 SRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVD 393
Query: 354 SP 355
SP
Sbjct: 394 SP 395
>UniRef50_Q39908 Cluster: CAMP-dependent protein kinase; n=1;
Gonyaulax polyedra|Rep: CAMP-dependent protein kinase -
Gonyaulax polyedra (Dinoflagellate)
Length = 332
Score = 238 bits (583), Expect = 1e-61
Identities = 116/281 (41%), Positives = 171/281 (60%), Gaps = 3/281 (1%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L+DF KVLG G++G V LV+ + YAMKML KE +++ Q+EH+ E+ +L +
Sbjct: 5 QLDDFTLVKVLGKGSYGKVMLVRGAQDNRLYAMKMLRKENVIKRNQVEHTKTERSVLETV 64
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + Y F+ LY V+ + GGE+F HL + G+F E +FY A+ A+ YLH
Sbjct: 65 SHPFIVTLHYAFQTPKKLYMVMEYCPGGELFFHLSRAGRFSEGRTRFYVAETSSAVAYLH 124
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKGY 231
++YRDLKPEN+LID G+ KITDFG K T+CGTPEYLAPEI+ KG+
Sbjct: 125 QLNVIYRDLKPENLLIDGEGHAKITDFGLRKEGIQDNHSAMTMCGTPEYLAPEILDKKGH 184
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G +VDW+S+G L +EM G PPF+ D +++++I G+ P + SV K+ + +LQ
Sbjct: 185 GKAVDWYSVGALTYEMLTGLPPFYTKDLQKLFDRIRRGELTYPDYVSVLAKEFLRALLQR 244
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
+ R G + K H++F +DW ++ I PPF P
Sbjct: 245 NPDARLAGGVPGGDEVKGHEFFGGLDWVALEKRAIPPPFKP 285
>UniRef50_Q16JU3 Cluster: Cgmp-dependent protein kinase; n=2;
Endopterygota|Rep: Cgmp-dependent protein kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 966
Score = 238 bits (582), Expect = 2e-61
Identities = 122/322 (37%), Positives = 188/322 (58%), Gaps = 9/322 (2%)
Query: 37 KLRQDFVESWDDKSESNA----KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
KL D DK+ S+ +L+D LG G FG V LV++ K +A+K L+K
Sbjct: 632 KLSDDLPRISGDKNTSSEYDHIQLHDLTYIGTLGIGGFGRVELVRY-QKQKTFALKYLKK 690
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
++VR +Q EH+Y EK I+ N PF+V + ++D YLY+++ GG++++ L+K
Sbjct: 691 IEMVRQQQQEHAYSEKDIMLSCNSPFIVRLYKTYRDKKYLYFLMEACLGGDVWTILQKSK 750
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGR 210
F+E +A+F V+ A EYLH+ ++YRDLKPEN+++D GYIK+ DFGF K I +
Sbjct: 751 HFDERTARFMAGCVVEAFEYLHSRNMIYRDLKPENLMLDEQGYIKLVDFGFAKRIGANQK 810
Query: 211 TWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG- 269
TWT GTPEY++PEIIL+KG+ +VD+W+LGV + E+ G PPF + M+ Y I+ G
Sbjct: 811 TWTFAGTPEYVSPEIILNKGHDRAVDYWALGVFIHELLVGKPPFRGKNHMKTYNAILRGI 870
Query: 270 -KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
PS + + +I + + R G K+G+ D KNH WF +W + +
Sbjct: 871 DIIELPSRIPKKAQVLIKRLCRQIPAERLGYGKNGIADIKNHPWFSGFEWQRLKERTLPA 930
Query: 329 PFFPKIRSPGDTTNFDVFDEEK 350
P I+S D +NFD + +++
Sbjct: 931 PLVRPIQSDTDLSNFDEYPKDQ 952
>UniRef50_O17874 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 1012
Score = 238 bits (582), Expect = 2e-61
Identities = 121/308 (39%), Positives = 180/308 (58%), Gaps = 10/308 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL---C 112
+ F VLG G FG V L +H T YYA+K+L+K I+ ++E EK+I
Sbjct: 681 VEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSS 740
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ N ++++ + + GG++ H+ F+E FY A V+L L++
Sbjct: 741 RARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHIHD-DVFDEVRGCFYAACVVLGLDF 799
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSK 229
LH ++YRD+K +N+L+DR GY+KI DFG CK G +T T CGTPE+LAPE++
Sbjct: 800 LHKHNIIYRDIKLDNLLLDREGYVKIADFGLCKENMGPFDKTSTFCGTPEFLAPEVLSDS 859
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y ++DWW LGVL+FEM G PPF D I++ I++ R P + SVE I+ +L
Sbjct: 860 SYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSVESIAIMRRLL 919
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREI--DWDSILNSRIHPPFFPKIRSPGDTTNFDV-F 346
+ +R G + D K ++FR I +WD +LN I PPF P+IR+P D +NFD+ F
Sbjct: 920 RKVPEKRLGYGERDAEDIKIQRFFRHISWEWDKLLNREIRPPFQPQIRNPEDVSNFDLEF 979
Query: 347 DEEKIKDS 354
+EK + S
Sbjct: 980 TQEKARFS 987
>UniRef50_A2DS63 Cluster: AGC family protein kinase; n=3;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 453
Score = 238 bits (582), Expect = 2e-61
Identities = 110/290 (37%), Positives = 171/290 (58%), Gaps = 1/290 (0%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++DF VLG G +G V LVK TGK +A+K + K + Q+E + E+ +L
Sbjct: 124 MDDFTILGVLGRGTYGKVQLVKEKETGKLFALKTMSKRLLAESDQVEQTITERNVLLTTK 183
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V Y F+ + ++ VL ++ GGE+F L++ F E+ + Y A++ L L YLH
Sbjct: 184 HPFLVCAHYTFQTDAKIFMVLDYVPGGELFGRLKEESLFAESRVRLYAAEICLGLGYLHK 243
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK-LIRGRTWTLCGTPEYLAPEIILSKGYGMS 234
+YRDLKPENIL+D+ G++KITDFG K G T T CGTPEY+APE++ Y +
Sbjct: 244 LGFIYRDLKPENILVDQDGHLKITDFGLAKNTDMGTTSTFCGTPEYIAPEMLQRLPYTKA 303
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTT 294
VDWWS G++++EM G PPF+ + ++Y I+ + PSH S + + +I +L +
Sbjct: 304 VDWWSYGIIIYEMLTGLPPFYDENTNQMYRSILRDDVKYPSHVSHDARSLINQLLNRNPE 363
Query: 295 RRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
R G+ + K H +F I+W+++ N + P + PKI++ DT+ FD
Sbjct: 364 ARLGSGPSDYEEIKAHPFFASINWENVFNKKTKPEWKPKIKNATDTSLFD 413
>UniRef50_P34885 Cluster: Protein kinase C-like 1B; n=4;
Bilateria|Rep: Protein kinase C-like 1B - Caenorhabditis
elegans
Length = 707
Score = 237 bits (581), Expect = 2e-61
Identities = 126/344 (36%), Positives = 204/344 (59%), Gaps = 14/344 (4%)
Query: 24 SPAKQEQYSQYLKKLRQDFVESWDDKSESNA-----KLNDFERQKVLGTGAFGIVFLVKH 78
S + + S YL+++ +D + +S S ++DF KVLG G+FG V L +
Sbjct: 338 SGSSNSENSGYLQQISEDDSGTTSSRSASKVPGGTLSIHDFTFMKVLGKGSFGKVMLAER 397
Query: 79 IVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLP 137
T + YA+K+L+K+ IV+ +E + EK+IL PF+ + F+ + L++V+
Sbjct: 398 KGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVME 457
Query: 138 FIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIK 197
++ GG++ +++ KF+E+ A+FY A+V AL++LH +++YRDLK +NIL+D G+ +
Sbjct: 458 YVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRNDVIYRDLKLDNILLDAEGHCR 517
Query: 198 ITDFGFCKLIRGR---TWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF 254
+ DFG CK + T T CGTP+Y+APEI+ YG+SVDWW+LGVL++EM AG PPF
Sbjct: 518 LADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPF 577
Query: 255 FASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTL--KDGVLDFKNHKW 312
A + ++E I+ P S E +I+ + + +R G + + G + H +
Sbjct: 578 EADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPF 637
Query: 313 FREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPV 356
FREIDWD++ + ++ PPF PKI+S D N FD + K+ PV
Sbjct: 638 FREIDWDALESRQVKPPFKPKIKSKRDANN---FDSDFTKEEPV 678
>UniRef50_Q23YB5 Cluster: Protein kinase domain containing protein;
n=8; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 551
Score = 237 bits (580), Expect = 3e-61
Identities = 137/377 (36%), Positives = 208/377 (55%), Gaps = 31/377 (8%)
Query: 7 KRHINS-PR--GDLIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQK 63
K++IN P+ G L+ H ++ E+ S + + V+ + +S+ +NDF K
Sbjct: 148 KKNINRMPQEGGVLLDHEQFNKLMNEKSSS----INNETVQIFPQQSKKGVTINDFNLLK 203
Query: 64 VLGTGAFGIVFLVKHIVTGKYYAMKMLEK--------------EKIVRLKQIEHSYYEKK 109
VLG GAFG V LV+ T K YA+K + K E I+ QIEH+ E+
Sbjct: 204 VLGRGAFGKVMLVEEKSTKKIYALKSIRKLASFLVGSLNKQNQEDIIDKDQIEHTKTERV 263
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL N PF+V + Y F +++V F+ GGE+F HL+ +F+E A+FY A++ LA
Sbjct: 264 ILEHCNHPFLVNLVYAFTTPEKIFFVTQFMKGGELFQHLKHAKRFDENRARFYVAEIALA 323
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR--TWTLCGTPEYLAPEIIL 227
L +LH ++YRDLKPENIL+D G+I +TDFG K++R + CGTPEYL+PEII
Sbjct: 324 LGHLHKKSIIYRDLKPENILMDEHGHICLTDFGMAKIVRKNELAMSFCGTPEYLSPEIIS 383
Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSV--ELKDII 285
G+ +S DWW+LG+ +EM PPF+ + ++++ I + R P ++ E ++ I
Sbjct: 384 GVGHTISCDWWALGIFTYEMLFALPPFYTQNQDQMFKAIKESQIRFPDKIAISPEAQNFI 443
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+ D +R GT D + + K+H W +DW+++LN PPF PK+
Sbjct: 444 LSCCKKDPHQRLGTHGD-LEEIKSHPWLAGMDWEALLNKTAEPPFKPKMEHWE-----HY 497
Query: 346 FDEEKIKDSPVCLYEEE 362
FDEE K+ P+ Y E
Sbjct: 498 FDEEFTKEEPINSYVPE 514
>UniRef50_Q04759 Cluster: Protein kinase C theta type; n=20;
Euteleostomi|Rep: Protein kinase C theta type - Homo
sapiens (Human)
Length = 706
Score = 236 bits (577), Expect = 8e-61
Identities = 116/294 (39%), Positives = 176/294 (59%), Gaps = 8/294 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
K+ DF K+LG G+FG VFL + T +++A+K L+K+ ++ +E + EK++L
Sbjct: 376 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA 435
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ +M F+ L++V+ ++ GG++ H++ KF+ + A FY A++IL L++L
Sbjct: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H+ +VYRDLK +NIL+D+ G+IKI DFG CK L +T T CGTP+Y+APEI+L +
Sbjct: 496 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWWS GVLL+EM G PF D ++ I P E KD++ +
Sbjct: 556 YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 615
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G D + H FREI+W+ + I PPF PK++SP D +NFD
Sbjct: 616 REPEKRLGVRG----DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
>UniRef50_UPI000150A8F4 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 399
Score = 235 bits (576), Expect = 1e-60
Identities = 114/292 (39%), Positives = 175/292 (59%), Gaps = 4/292 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++ F ++G G++ V LV+ + YA+K ++K I Q EH E+ IL +N
Sbjct: 41 MDSFYLLSIIGKGSYAKVSLVRKKDDNQVYALKAIKKSLIEAKNQKEHIITERNILQTVN 100
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
++V MKY F+D L++VL + GGE++S L E KFY AQ++ A+EYLH+
Sbjct: 101 NQYIVKMKYAFQDKQKLFFVLEYCGGGELYSLLSSKKYLNEQQTKFYAAQLVKAIEYLHS 160
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRT--WTLCGTPEYLAPEIILSKGYG 232
++YRDLKPENILID+ GYIK+TDFG K+ I+ T +LCGTPEYLAPEI+ G+G
Sbjct: 161 HNIIYRDLKPENILIDKDGYIKLTDFGLSKMDIKHNTEATSLCGTPEYLAPEILEQSGHG 220
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
VDWW+LG +++EM G PPF+ + ++ I + +LK+++ +L+ D
Sbjct: 221 KPVDWWTLGNIIWEMMTGLPPFYNENRKEMFHHIKELPLKNHPRIQGDLKNLLHSLLEKD 280
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+R GT+ DG + +H WF+++ WD + +I+PPF P + + D D
Sbjct: 281 PNKRLGTI-DGAKEIIDHPWFKDLRWDQLEQRKINPPFVPNLETDIDLKYID 331
>UniRef50_A0DLX8 Cluster: Chromosome undetermined scaffold_56, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_56,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 371
Score = 235 bits (576), Expect = 1e-60
Identities = 124/294 (42%), Positives = 183/294 (62%), Gaps = 19/294 (6%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+ FE V+G G + V LV+ T YA+K+L+K LKQ + E+ I+ +
Sbjct: 24 LDSFEMNCVIGKGQYAKVLLVRKKDTKHLYALKVLKKSG---LKQ--DARIERNIMIEIQ 78
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ + Y F+ +LY+ + + GGEM+ L K F E +A FY AQ+ILALEYLH+
Sbjct: 79 HPFIIKLVYAFQTASHLYFCMEYCPGGEMYYLLSKQKHFSEHTAMFYAAQIILALEYLHS 138
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKL-----IRGRTWTLCGTPEYLAPEIILSKG 230
+++RDLKPENI+I + GY+K+TDFG CK I G + ++CGTP Y+APEI+LSK
Sbjct: 139 KGIIFRDLKPENIVICQDGYVKLTDFGLCKKGDFTNISGAS-SICGTPAYMAPEILLSKQ 197
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
YG +VDWW+ G L+EM AGHPPFFAS+ + IV + HFS++L+D++ +L+
Sbjct: 198 YGKAVDWWAFGCFLYEMVAGHPPFFASNKQDLEYSIVNSQPNM-GHFSIKLQDLLYRLLE 256
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ R T + ++H+WF ID+D+ILN + PF P +++ D T FD
Sbjct: 257 KNPKNRLTT------NVRDHQWF-NIDFDAILNKKETAPFLPTLQNEADVTYFD 303
>UniRef50_Q584T1 Cluster: Rac serine-threonine kinase, putative;
n=5; Trypanosoma|Rep: Rac serine-threonine kinase,
putative - Trypanosoma brucei
Length = 458
Score = 235 bits (575), Expect = 1e-60
Identities = 126/326 (38%), Positives = 190/326 (58%), Gaps = 22/326 (6%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
+ LNDF+ +G G+F V+ TGK YA+K +EKE I R I++ E+ IL
Sbjct: 127 NRVSLNDFQFAAKIGKGSFSSVYAATEKATGKTYAIKKMEKEVIERYNMIDNISAERLIL 186
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
++ PF+V + Y F+ LY V+ F++GGE+F HL + F+E AKFY ++ LAL
Sbjct: 187 QKIDHPFIVSLHYAFQTKGSLYLVMDFLSGGELFFHLESVSVFDEWRAKFYCGEIALALG 246
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGR-TWTLCGTPEYLAPEIILSK 229
YLHA +++YRDLKPEN ++D G++ +TDFG K+ +R +T CGTPEY+APE +L K
Sbjct: 247 YLHAQDIIYRDLKPENAVLDADGHVCLTDFGLAKMDVRDACNFTFCGTPEYIAPEFLLGK 306
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA----------GKYRCPSHFSV 279
+G +VDWWSLG+LL+EM G PPF++ + +Y+KI++ G P S
Sbjct: 307 PHGKAVDWWSLGILLYEMLEGIPPFYSENVSAMYDKILSSELQFGDGEGGSNNMP-QISE 365
Query: 280 ELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGD 339
E +D++ +L + R L+D V + K H +FR++DW+ + I PPF P
Sbjct: 366 EAQDLLRRLLDRNPDTR---LQD-VEELKGHPFFRDLDWEKLFRREIEPPFRP---DGNA 418
Query: 340 TTNFDVFDEEKIKDSPVCLYEEEFAD 365
+NFD E D P+ ++E +
Sbjct: 419 LSNFD--QEFTSADPPMVQPDDEVVE 442
>UniRef50_A0DTL3 Cluster: Chromosome undetermined scaffold_63, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_63,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 865
Score = 235 bits (575), Expect = 1e-60
Identities = 116/322 (36%), Positives = 192/322 (59%), Gaps = 10/322 (3%)
Query: 30 QYSQYLKKLRQDFVESWDDK-SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
Q SQ ++L ++S ++ +S + FE K LG+GAFG VFLVKH G +AMK
Sbjct: 510 QISQSQQQLTSSVMDSQNELLKDSKVNFDSFEIIKELGSGAFGKVFLVKHKADGNIFAMK 569
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
L+K+ ++ KQI+++ E +L PF++ + + F+ YLY VL + GG++ H+
Sbjct: 570 ALKKKTLILKKQIKYAITEANVLKMCKHPFILGLHFAFQTPNYLYLVLDYCQGGDLSYHI 629
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--- 205
+GKF E +A+FY A+++LA+E+LH +++YRD+KPENIL+D G++K+ DFG K
Sbjct: 630 ANLGKFSEDTARFYAAEILLAIEFLHTKDIIYRDMKPENILLDSQGHVKLADFGLSKEGV 689
Query: 206 LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK 265
+ + + CG+P YL+P+I+ KG G D + +G +++EM G P++ D ++Y+
Sbjct: 690 SDQDKAKSFCGSPAYLSPDILSQKGAGKPSDIYGIGCVMYEMMTGESPYYNDDIQQMYKN 749
Query: 266 IVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGT-LKDGVLDFKNHKWFREIDWDSILNS 324
I +G + P SVE K+++ +L+ D +R GT KD + K +F+ IDWD +
Sbjct: 750 IQSGTLKWPKKMSVEAKNLLTKMLERDPNKRIGTKSKD---EIKQDPFFKGIDWDKVYKR 806
Query: 325 RIHPPF--FPKIRSPGDTTNFD 344
+ PP F ++ D +FD
Sbjct: 807 QYKPPITDFSEMHDDDDQQDFD 828
>UniRef50_P83099 Cluster: Putative protein kinase C delta type
homolog; n=3; Endopterygota|Rep: Putative protein kinase
C delta type homolog - Drosophila melanogaster (Fruit
fly)
Length = 671
Score = 235 bits (575), Expect = 1e-60
Identities = 114/309 (36%), Positives = 185/309 (59%), Gaps = 5/309 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
N ++DF VLG G+FG V L + T YYA+K L+K+ ++ ++ + E+K+L
Sbjct: 337 NYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLA 396
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
G P++ ++ F+ +L++V+ ++ GG++ H+++ G+F E A+FYGA++I L+
Sbjct: 397 LGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLK 456
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEIILS 228
+LH ++YRDLK +N+L+D G+++I DFG CKL + + CGTP+Y+APEII
Sbjct: 457 FLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKG 516
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWWS GVLL+EM G PF D ++ I P + S E I+ +
Sbjct: 517 EKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGL 576
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L+ D T+R G+ D +H +FR IDW + +I PPF P+++ P DT FD VF
Sbjct: 577 LEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFT 636
Query: 348 EEKIKDSPV 356
E+++ +P+
Sbjct: 637 RERVRLTPI 645
>UniRef50_UPI00015A51B8 Cluster: Protein kinase C delta type (EC
2.7.11.13) (nPKC-delta).; n=1; Danio rerio|Rep: Protein
kinase C delta type (EC 2.7.11.13) (nPKC-delta). - Danio
rerio
Length = 649
Score = 235 bits (574), Expect = 2e-60
Identities = 115/299 (38%), Positives = 179/299 (59%), Gaps = 9/299 (3%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S LNDF QKVLG G+FG V L + G+Y+A+K L+K+ ++ +E + EK+
Sbjct: 314 STVRVSLNDFVFQKVLGKGSFGKVMLAELKGKGQYFAIKALKKDVVLMDDDVECTMVEKR 373
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L PF+ ++ F+ +L++V+ ++ GG++ H++ G+F+ A FY A++I
Sbjct: 374 VLALAWENPFLTHLYCTFQSKEHLFFVMEYLNGGDLMFHIQDKGRFDLYRATFYAAEIIC 433
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
L+YLH+ +VYRDLK +N+++D+ G+IKI DFG CK + R T CGTP+Y+APEI
Sbjct: 434 GLQYLHSKGIVYRDLKLDNVMLDKDGHIKIADFGMCKENMIGENRATTFCGTPDYIAPEI 493
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+L + Y SVDWWS GVLL+EM G PF D +++ I P + E KD++
Sbjct: 494 LLGQKYSFSVDWWSFGVLLYEMLIGQSPFQGDDEDELFDSIRMDVPHYPRWITKEAKDLL 553
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ + D TRR G V + + H +F+ I+W ++ + PPF PK +S D +NFD
Sbjct: 554 EKLFERDPTRRLGV----VGNIRGHAFFKTINWPALEKREVSPPFKPK-KSSSDCSNFD 607
>UniRef50_UPI00015B57E6 Cluster: PREDICTED: similar to protein
kinase c; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to protein kinase c - Nasonia vitripennis
Length = 990
Score = 234 bits (573), Expect = 2e-60
Identities = 124/307 (40%), Positives = 177/307 (57%), Gaps = 8/307 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L +F VLG G FG V L ++ TG+Y+A+K L+K I+ ++E EK+I N
Sbjct: 660 LENFRLLSVLGRGHFGKVILSQYRNTGEYFAIKALKKGDIIARDEVESLLSEKRIFEVAN 719
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ + ++ +V+ + AGG++ H+ F E A FY A V+L L+Y
Sbjct: 720 ATRHPFLVNLFACFQTDAHVCFVMEYAAGGDLMMHIHA-DVFGEPRAVFYSACVVLGLQY 778
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSK 229
LH ++YRDLK +N+L+D GY+KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 779 LHESRIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTET 838
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW LGVL+FEM G PF D +++ IV + R P S+E I+ +L
Sbjct: 839 SYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAIMRRLL 898
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDE 348
+ + RR G+ + D K +FR I WD +L R+ PPF P I S D +NFD F
Sbjct: 899 RKNPDRRLGSSERDAEDVKKQAFFRHIAWDDLLLRRVKPPFVPVIHSVEDVSNFDEEFTS 958
Query: 349 EKIKDSP 355
EK + +P
Sbjct: 959 EKPQLTP 965
>UniRef50_Q8MMZ4 Cluster: CGMP-dependent protein kinase; n=14;
Apicomplexa|Rep: CGMP-dependent protein kinase -
Plasmodium falciparum
Length = 853
Score = 234 bits (572), Expect = 3e-60
Identities = 111/315 (35%), Positives = 182/315 (57%), Gaps = 3/315 (0%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
++ ++++ E ++++G G FG V LV H T YA+K + K I+ L Q + E++I
Sbjct: 533 DTKVEMDELETERIIGRGTFGTVKLVHHKPTKIRYALKCVSKRSIINLNQQNNIKLEREI 592
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ PF++ + FKD+ Y Y++ + GGE++ +RK+G ++ A+FY +ILA+
Sbjct: 593 TAENDHPFIIRLVRTFKDSKYFYFLTELVTGGELYDAIRKLGLLSKSQAQFYLGSIILAI 652
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKG 230
EYLH +VYRDLKPENIL+D+ GY+K+ DFG K ++GR +TL GTP Y+APE+IL KG
Sbjct: 653 EYLHERNIVYRDLKPENILLDKQGYVKLIDFGCAKKVQGRAYTLVGTPHYMAPEVILGKG 712
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPF--FASDPMRIYEKIVAGKYRCPSHFS-VELKDIIGH 287
YG +VD W+LG+ L+E G PF D + I+ I+ G+ P + + + +++
Sbjct: 713 YGCTVDIWALGICLYEFICGPLPFGNDEEDQLEIFRDILTGQLTFPDYVTDTDSINLMKR 772
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFD 347
+L R G +G D K+H +F +WD + + PP K + + + +
Sbjct: 773 LLCRLPQGRIGCSINGFKDIKDHPFFSNFNWDKLAGRLLDPPLVSKSETYAEDIDIKQIE 832
Query: 348 EEKIKDSPVCLYEEE 362
EE +D L +E+
Sbjct: 833 EEDAEDDEEPLNDED 847
>UniRef50_Q24DD1 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 449
Score = 233 bits (570), Expect = 5e-60
Identities = 119/288 (41%), Positives = 180/288 (62%), Gaps = 12/288 (4%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S N + DF + LG GAFG V+LV + + YAMK ++K +V+L+ IE + EK
Sbjct: 95 SRKNLSIQDFVIDRPLGKGAFGQVYLVTKKDSQRKYAMKTIKKIDMVKLQLIEATILEKT 154
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL + PF+V +KY + +Y ++ +I GGE+F+ L+ G+F E AKF A++IL
Sbjct: 155 ILLKSSHPFIVQLKYCIQTEKKIYLIMEYIQGGELFTLLKHCGQFTEKVAKFIIAEIILG 214
Query: 170 LEYLH-ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEI 225
++YLH +++YRD+KPENIL+ ++G+IKI+DFG K + +T+T GTPEYLAPEI
Sbjct: 215 IQYLHETLKIIYRDIKPENILLTKSGHIKISDFGLSKEFQNKDEKTYTFAGTPEYLAPEI 274
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK----IVAGKYRCPSHFSVEL 281
+L+KG+ +VD W +GV L+E+ AG+PPF D R Y+K I+ + P +FS L
Sbjct: 275 VLNKGHNKNVDLWGIGVFLYELVAGYPPF--QDKNRNYDKISKQIIMNRPTYPENFSPNL 332
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
KD+I +L D R G + D K H +F ++DW+++ N +I P
Sbjct: 333 KDLIKKLLNSDPQMRLGA--NSFTDLKEHPFFYDVDWEALENLKIESP 378
>UniRef50_UPI0001509D2B Cluster: Protein kinase C terminal domain
containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Protein kinase C terminal domain containing
protein - Tetrahymena thermophila SB210
Length = 408
Score = 233 bits (569), Expect = 7e-60
Identities = 128/315 (40%), Positives = 182/315 (57%), Gaps = 8/315 (2%)
Query: 36 KKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI 95
KKL Q + E L+ F +V+G+GAFG V+LV T + YAMK+ +K +
Sbjct: 42 KKLFQSQAGNHSLGEEEKITLSSFRIIRVIGSGAFGKVYLVNKKGTEEVYAMKVYDKMTL 101
Query: 96 VRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFE 155
I + E+ IL +N F+V + Y F+ LY ++ F+ GGE++ HL+K KF+
Sbjct: 102 YEKNVILSTIGERNILKNMNSNFIVKLHYAFQAAQNLYLMMDFMVGGELYYHLKKAKKFD 161
Query: 156 ETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGR--TW 212
E KFY AQVILA+E LH ++YRDLK ENIL+ + GYIK+TDFG K I+ + T
Sbjct: 162 EERTKFYIAQVILAIECLHQNNIMYRDLKLENILLGQDGYIKLTDFGLSKEGIKDKDLTN 221
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAG 269
TLCGT EY+APE I+++G+ D+W +GVL +EM G PF F + I+ I+ G
Sbjct: 222 TLCGTAEYMAPEQIMNEGHNKMADFWQIGVLTYEMLYGTTPFFNEFRPNKDEIFNDIIQG 281
Query: 270 KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
KY P +F + K+ I +LQ D +R G +G + K H +F + DWD + I P
Sbjct: 282 KYTFPQYFKDDAKNFIRGLLQKDVKKRLG--YNGFHELKKHAFFADFDWDKLERQEIEPQ 339
Query: 330 FFPKIRSPGDTTNFD 344
F P +RS D NF+
Sbjct: 340 FKPPLRSQVDLQNFN 354
>UniRef50_Q1MX42 Cluster: Protein kinase C, delta V; n=9;
Euteleostomi|Rep: Protein kinase C, delta V - Mus
musculus (Mouse)
Length = 585
Score = 233 bits (569), Expect = 7e-60
Identities = 113/300 (37%), Positives = 176/300 (58%), Gaps = 8/300 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
+ + L +F QKVLG G+FG V L + KY+A+K L+K+ ++ +E + EK
Sbjct: 248 EGSTRCTLENFTFQKVLGKGSFGKVLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEK 307
Query: 109 KILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
++L PF+ ++ F+ +L++V+ F+ GG++ H++ G+FE A FY A++I
Sbjct: 308 RVLALAWESPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEII 367
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPE 224
L++LH+ ++YRDLK +N+++DR G+IKI DFG CK GR T CGTP+Y+APE
Sbjct: 368 CGLQFLHSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPE 427
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
I+ Y SVDWWS GVLL+EM G PF D ++E I P + E KDI
Sbjct: 428 ILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDI 487
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ + + D +R G + + H +F+ I+W + ++ PPF PK++SP D +NFD
Sbjct: 488 MEKLFERDPDKRLGVTG----NIRIHPFFKTINWSLLEKRKVEPPFKPKVKSPSDYSNFD 543
>UniRef50_Q21694 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 402
Score = 233 bits (569), Expect = 7e-60
Identities = 118/294 (40%), Positives = 181/294 (61%), Gaps = 12/294 (4%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRL-KQIEHSYYEKKILCG 113
DFER K++G G +G VF V+ G YAMK++ K K+ K + H+ E+KIL
Sbjct: 48 DFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKILET 107
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+N PF+ + Y F+ N LY VL F+ GGE+++ L + + E A+FY +++ILA+E+L
Sbjct: 108 INSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIILAIEHL 167
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFC--KLIRG-RTWTLCGTPEYLAPEIILSKG 230
H ++VYRDLKP+N++++ G++ +TDFG C KL +G +T T CGT EY+APE+I G
Sbjct: 168 HGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKTLTFCGTHEYMAPEMIRKVG 227
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ +VD W+LG+L+++M G PPF P + I+ GK R P S KD+I +++
Sbjct: 228 HDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLPPKLSASGKDLIKRIIK 287
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
D TL+ + D K H++F EIDWD ++ PPF P + + D ++FD
Sbjct: 288 RDP-----TLRITIPDIKEHEFFEEIDWDKLMAHDFEPPFKPTLANLEDVSHFD 336
>UniRef50_Q12706 Cluster: Serine/threonine-protein kinase psk1; n=1;
Schizosaccharomyces pombe|Rep: Serine/threonine-protein
kinase psk1 - Schizosaccharomyces pombe (Fission yeast)
Length = 436
Score = 233 bits (569), Expect = 7e-60
Identities = 128/329 (38%), Positives = 188/329 (57%), Gaps = 9/329 (2%)
Query: 41 DFVESWDDKSESNAKLN--DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIV-R 97
DF+ S D + K+ DF+ VLG G++G V LVK TG+ +A K L+K IV R
Sbjct: 71 DFISSKGDNYVPSGKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLR 130
Query: 98 LKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEET 157
K +E + E++IL + PF+ + Y F+D+ LY +L + GGE+FSHL + E
Sbjct: 131 AKGLEQTKNERQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPED 190
Query: 158 SAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRT--WTLC 215
FY A++ LAL +LH +VYRDLKPEN L+D G+I +TDFG K+ +
Sbjct: 191 VVAFYTAELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCRSFV 250
Query: 216 GTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPS 275
GT EY APEI+L + Y +VDWWS+G+L+F++ G PPF A++ RI EKI K P
Sbjct: 251 GTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPF 310
Query: 276 HFSVELKDIIGHVLQVDTTRRYGT--LKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
+ + + +DII L+ + +R G + G K H+ +R IDW+ + + PP P
Sbjct: 311 YVTSDARDIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPC 370
Query: 334 IRSPGDTTNFDV-FDEEKIKDSPVCLYEE 361
I +P NF V F + + +P+ L+EE
Sbjct: 371 ITNPEAAENFSVEFTKLPLSTTPI-LHEE 398
>UniRef50_O61224 Cluster: Serine/Threonine protein kinase; n=1;
Sycon raphanus|Rep: Serine/Threonine protein kinase -
Sycon raphanus
Length = 756
Score = 232 bits (567), Expect = 1e-59
Identities = 118/306 (38%), Positives = 180/306 (58%), Gaps = 5/306 (1%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
KL+DF KVLG G+FG V L + +YYA+K+L+K+ IV+ +E + EK++L
Sbjct: 362 KLSDFSFLKVLGKGSFGKVMLAQLKGQEQYYAIKVLKKDVIVQDDDVECTMIEKRVLALS 421
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ + F+ L++V+ F+ GG++ H+++ G+F+E A FY A+++L L +L
Sbjct: 422 GKPPFLTALHSTFQTKDRLFFVMEFVNGGDLMYHIQQQGRFKENVAVFYSAEIVLGLFFL 481
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H ++YRDLK +N+++D G+IKI DFG CK L +T T CGTP+Y+APEI+ +
Sbjct: 482 HRHGVIYRDLKLDNVMLDHEGHIKIADFGMCKEGVLGAKQTRTFCGTPDYIAPEIVAYQP 541
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWW+LGVL++EM +G PPF D ++ I+ + R P + E I L
Sbjct: 542 YNGSVDWWALGVLVYEMLSGQPPFDGEDEDELFSSILGDEVRFPKSMTREACSICKSFLA 601
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
R G +G D + H ++R IDW + + PPF P+I+S NFD F +E
Sbjct: 602 KHPAVRLGCGPNGEADIQGHPFYRTIDWTRLGRRELPPPFKPRIKSKNAANNFDKEFTDE 661
Query: 350 KIKDSP 355
K +P
Sbjct: 662 HPKLTP 667
>UniRef50_Q9UK32 Cluster: Ribosomal protein S6 kinase alpha-6;
n=145; Eumetazoa|Rep: Ribosomal protein S6 kinase
alpha-6 - Homo sapiens (Human)
Length = 745
Score = 232 bits (567), Expect = 1e-59
Identities = 123/304 (40%), Positives = 174/304 (57%), Gaps = 10/304 (3%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
FE KVLG G+FG VFLV+ G+ YAMK+L+K + +++ + E+ IL +N
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASL-KVRDRVRTKMERDILVEVN 131
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKGYG 232
+VYRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+APE++ +G+
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S DWWS GVL+FEM G PF D I+ K P S E + ++ + + +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
R G+ +GV + K H +F IDWD + + PPF P P DT FD F +
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTP 369
Query: 352 KDSP 355
KDSP
Sbjct: 370 KDSP 373
Score = 123 bits (297), Expect = 6e-27
Identities = 80/253 (31%), Positives = 129/253 (50%), Gaps = 20/253 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE ++ P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEI------LMRYGQHPN 479
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K F D Y+Y V + GGE+ + K F E A + ++YLH +
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D + I+I DFGF K +RG L C T ++APE+++ +GY
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLGVL + M AG+ PF P I +I GK+ + S KD+
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDL 659
Query: 285 IGHVLQVDTTRRY 297
+ H+L +D +RY
Sbjct: 660 LSHMLHMDPHQRY 672
>UniRef50_UPI0000499868 Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 441
Score = 231 bits (566), Expect = 2e-59
Identities = 118/320 (36%), Positives = 187/320 (58%), Gaps = 11/320 (3%)
Query: 36 KKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI 95
K ++ +E ++ E + DF+ +LG GAFG V LV++ TG+ +A+KM+EK+K+
Sbjct: 97 KNKKETLIEK--EEEEKPISIEDFDIITLLGKGAFGKVLLVRYKRTGEKFALKMVEKKKV 154
Query: 96 VRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFE 155
+ ++++EH+ EK IL + PF+V + Y F+ +L+YV+ + GGE++ L + F
Sbjct: 155 IEMEELEHTMTEKNILQKVKHPFLVNLYYSFQSATHLHYVIDYCPGGELYYRLIQEKSFC 214
Query: 156 ETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK-LIRGR--TW 212
E+ +FY +QVILALE LH ++YRD+K EN+LI GY+++TDFG K + G T
Sbjct: 215 ESRTQFYISQVILALECLHQMNIIYRDVKLENVLICEDGYLRLTDFGLSKENVSGNETTA 274
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR 272
T CGTPEYL+PE++L++ Y +DWW +G++ +EM G PF + + ++Y+KI+
Sbjct: 275 TFCGTPEYLSPEVVLAEPYTNVIDWWGVGIMTYEMMHGQAPFISDNIQQLYQKILYSPVI 334
Query: 273 CP--SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPF 330
P S S KD I +L+ R T + K H W+ DWD++ +I PF
Sbjct: 335 FPTTSPVSAVCKDFITKMLEKKICDRLSTPE----KIKTHPWWNSFDWDALYQKKIPAPF 390
Query: 331 FPKIRSPGDTTNFDVFDEEK 350
P + G T + F EK
Sbjct: 391 KPDMSQDGKTNFGEEFINEK 410
>UniRef50_A0E8L1 Cluster: Chromosome undetermined scaffold_83, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_83,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 569
Score = 231 bits (566), Expect = 2e-59
Identities = 108/300 (36%), Positives = 184/300 (61%), Gaps = 4/300 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
+ L DF+ K +G G F V+LV+ + G +YAMK+++KE I++ K+ E E+ I+
Sbjct: 156 HVSLKDFQILKCIGAGGFSKVYLVRSKMNGHFYAMKLVDKEFIIKYKKAELLQNERDIMA 215
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
++ PF + M + F+ ++ ++L F +GGE+F L+ + + E A+FY ++ +++ Y
Sbjct: 216 FIHHPFTIQMLFSFESRNFVVFILEFCSGGELFYQLKTLKRMSEEQAQFYFVEICISMLY 275
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR--TWTLCGTPEYLAPEIILSKG 230
LH ++YRD+KPENIL+D G+I+I+DFG KL ++ CG+PEY+APE++L +G
Sbjct: 276 LHQMGIMYRDIKPENILLDLDGHIRISDFGLSKLTTPDEFAYSFCGSPEYMAPEMLLKRG 335
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ + VD + LG LL+E+ G PPF++ + +IY+ I+ + P S E+KD++ +L
Sbjct: 336 HTIQVDHYCLGALLYELVTGLPPFYSKNTQKIYDSILNEQVTFPQFLSQEIKDLMSGLLA 395
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPG-DTTNFDVFDEE 349
D +R G ++ GV + HKWF++++ IL R+ PP P I+ +T N D E
Sbjct: 396 KDPHKRLG-VRGGVREILQHKWFKKVNLTDILMKRVTPPIRPDIQKLNFETKNLQQGDLE 454
>UniRef50_A1CKA9 Cluster: Serine/threonine protein kinase, putative;
n=13; Pezizomycotina|Rep: Serine/threonine protein
kinase, putative - Aspergillus clavatus
Length = 599
Score = 231 bits (565), Expect = 2e-59
Identities = 121/307 (39%), Positives = 180/307 (58%), Gaps = 8/307 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI-VRLKQIEHSYYEKKILCGLN 115
+DFE LG G+FG V LV+H +TGK YA K K + V K +E + E+ IL +N
Sbjct: 235 SDFEPLLCLGKGSFGTVLLVRHALTGKLYAQKQFRKASLTVHKKLVEQTKTERAILESVN 294
Query: 116 -FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PFVV + Y F+D+ LY +L + GGE+F HL F+E +A FY A+++LALE+LH
Sbjct: 295 RHPFVVKLFYAFQDHEKLYLILEYAQGGELFHHLAIERMFDEDTAAFYMAEMVLALEHLH 354
Query: 175 A-CELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKG 230
++YRDLKPEN L+D G++ +TDFG K+ R + GT EY+APE+I K
Sbjct: 355 QNVGVIYRDLKPENCLLDHEGHLLLTDFGLSKIAVNDDDRCNSSLGTIEYMAPEVIQGKS 414
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
YG + DWWSLG L +++ G PPF A++ ++ EKI+ K P + KD++ +++
Sbjct: 415 YGKACDWWSLGALGYDLLTGSPPFKANNHAKLQEKIIKQKLALPYFLGPDAKDLLTRLMR 474
Query: 291 VDTTRRYG-TLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ +R G + + KNH++FR+IDW ++ + PP P + P NF + D
Sbjct: 475 KEPAKRLGYHMPKDLQTIKNHRFFRKIDWKALERREVAPPILPVVTDPALAENFSM-DFT 533
Query: 350 KIKDSPV 356
+ SPV
Sbjct: 534 TLPLSPV 540
>UniRef50_A2F9U6 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 279
Score = 231 bits (564), Expect = 3e-59
Identities = 111/267 (41%), Positives = 156/267 (58%)
Query: 90 LEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLR 149
+ K +I++L+Q+EH EK IL L+ P +V + F+D +LY ++ FIAGGE+FSHLR
Sbjct: 1 MNKRQIIQLEQVEHVKNEKNILSILHHPNIVTVYGTFQDENFLYIMMEFIAGGEVFSHLR 60
Query: 150 KMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG 209
F+ + +FY A+V + E +H +VYRDLKPEN+L D G+IK DFGF K+I
Sbjct: 61 TNECFDPDTVRFYAAEVFMVFEEMHKNNIVYRDLKPENLLFDAGGHIKFIDFGFAKIIEE 120
Query: 210 RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG 269
RT+TLCGTPEYLAPEII +G + DWWS GVL+ E+ GH PF +Y I G
Sbjct: 121 RTYTLCGTPEYLAPEIIRGEGTTFASDWWSYGVLIHELICGHTPFAQLPEDDLYRSICEG 180
Query: 270 KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
P + + + +D TRR G+ G + KNH +F IDW+ + + P
Sbjct: 181 VSEYPPEVDEATANFLDALFALDPTRRLGSGSAGTDEIKNHPYFEGIDWNKMRAHQYQTP 240
Query: 330 FFPKIRSPGDTTNFDVFDEEKIKDSPV 356
P + SP DT+NF F + + P+
Sbjct: 241 LIPMVTSPYDTSNFADFTSQVPEYEPL 267
>UniRef50_P24723 Cluster: Protein kinase C eta type; n=44;
Eumetazoa|Rep: Protein kinase C eta type - Homo sapiens
(Human)
Length = 682
Score = 231 bits (564), Expect = 3e-59
Identities = 120/312 (38%), Positives = 189/312 (60%), Gaps = 8/312 (2%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S + +++FE +VLG G+FG V L + TG YA+K+L+K+ I+ +E + EK+
Sbjct: 345 SSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKR 404
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
IL N PF+ + F+ L++V+ F+ GG++ H++K +F+E A+FY A++I
Sbjct: 405 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIIS 464
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEI 225
AL +LH ++YRDLK +N+L+D G+ K+ DFG CK + G T T CGTP+Y+APEI
Sbjct: 465 ALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEI 524
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ YG +VDWW++GVLL+EM GH PF A + ++E I+ + P+ + I+
Sbjct: 525 LQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGIL 584
Query: 286 GHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ + T R G+L + G H +F+EIDW + + +I PPF P+I+S D +N
Sbjct: 585 KSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSN-- 642
Query: 345 VFDEEKIKDSPV 356
FD + IK+ PV
Sbjct: 643 -FDPDFIKEEPV 653
>UniRef50_Q4SYX7 Cluster: Chromosome 21 SCAF11909, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 21
SCAF11909, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1114
Score = 230 bits (563), Expect = 4e-59
Identities = 126/318 (39%), Positives = 182/318 (57%), Gaps = 32/318 (10%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLE-----KEKIV---------------- 96
DF+ K++G G+FG V L +H T KYYA+K+L+ K+K V
Sbjct: 6 DFDYLKIIGKGSFGKVLLARHKETTKYYAVKVLQKKIIIKKKEVSARGAPSSPPVPEDVR 65
Query: 97 ------RLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLR 149
RL Q +H E+ +L + PF+V + Y F+ LY+VL ++ GGE+F HL+
Sbjct: 66 VILNRKRLLQQKHIMAERSVLMKNIKHPFLVGLHYSFQTTDKLYFVLDYVNGGELFYHLQ 125
Query: 150 KMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---L 206
+ F E A+FY A++ AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK
Sbjct: 126 RERIFLEPRARFYAAEIASALGYLHSLHIVYRDLKPENILLDSQGHIVLTDFGLCKEGLE 185
Query: 207 IRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKI 266
G T T CGTPEYLAPE++ + Y +VDWW LG +L+EM G PPF++ + +Y I
Sbjct: 186 ANGTTTTFCGTPEYLAPEVLQKQAYDRTVDWWCLGSVLYEMLYGLPPFYSRNTAEMYNNI 245
Query: 267 VAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRI 326
+ + S ++++ +LQ D RR G +KD L+ K H +F I+W+ ++ RI
Sbjct: 246 LHKSPVLKPNVSNAGRELLEGLLQKDRARRLG-VKDDFLELKFHSFFSPINWEDLMAKRI 304
Query: 327 HPPFFPKIRSPGDTTNFD 344
PPF P + P D +FD
Sbjct: 305 TPPFVPSVSGPTDLRHFD 322
>UniRef50_Q8MMZ5 Cluster: CGMP-dependent protein kinase; n=2;
Eimeria|Rep: CGMP-dependent protein kinase - Eimeria
maxima
Length = 1007
Score = 230 bits (563), Expect = 4e-59
Identities = 109/286 (38%), Positives = 170/286 (59%), Gaps = 3/286 (1%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
++ + D + +V+G G FG V LV+HI T YA+K + ++ +V L Q +H E++I
Sbjct: 689 DTKVEFKDLQVVRVVGRGTFGTVKLVQHIPTKIRYALKCVSRKSVVALNQQDHIRLEREI 748
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ + PF++ + F+D +LY++ + GGE++ +RK+G A+FY A ++LA+
Sbjct: 749 MAENDHPFIIRLVRTFRDKDFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAI 808
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKG 230
EYLH + YRDLKPENIL+D GY+K+ DFG K ++GR +TL GTP Y+APE+IL KG
Sbjct: 809 EYLHERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKG 868
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPF--FASDPMRIYEKIVAGKYRCPSHFS-VELKDIIGH 287
Y ++ D W+ GV L+E G PF A D + I+ I+AGK P + + + +++
Sbjct: 869 YTLTADTWAFGVCLYEFMCGPLPFGNDAEDQLEIFRDILAGKLMFPHYVTDQDAINLMKR 928
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
+L R G +G D K H +F + DWD + + PP PK
Sbjct: 929 LLCRLPEVRIGCSINGYKDIKEHAFFSDFDWDRLAGRDLSPPLLPK 974
>UniRef50_A7SL27 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 710
Score = 230 bits (563), Expect = 4e-59
Identities = 119/306 (38%), Positives = 187/306 (61%), Gaps = 6/306 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GL 114
L DF KVLG G+FG V L + T + YA+K+L+KE +++ +E + E+++L
Sbjct: 380 LKDFTFIKVLGKGSFGKVLLAERKGTDEVYAIKILKKESVLQDDDVECTMIERRVLALSA 439
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF+ + F+ L++V+ ++ GG++ ++K KF+E ++FY A+V+LAL++LH
Sbjct: 440 GHPFLTSLHSSFQTVERLFFVMEYVNGGDLMFQIQKSRKFDENRSRFYAAEVVLALQFLH 499
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+ DFG CK + G+ T T CGTP+Y+APEI+ + Y
Sbjct: 500 QNGVIYRDLKLDNVLLDADGHIKLADFGMCKENMAPGKTTTTFCGTPDYIAPEILQEQPY 559
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G SVDWW+LGVL++EM AG PPF A + ++E I+ P S E I+ +
Sbjct: 560 GFSVDWWALGVLMYEMMAGQPPFEAENEEDLFESILHDDVLYPVWLSREAVSILKGFMTK 619
Query: 292 DTTRRYG-TLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEE 349
+ +R G T + H +FR I+++ + +I+PPF PKIRS D NFD F +E
Sbjct: 620 NYLKRLGCTPTSTESSIREHAFFRLINFEKLEARQINPPFKPKIRSRTDVGNFDTDFTKE 679
Query: 350 KIKDSP 355
+ K +P
Sbjct: 680 EPKLTP 685
>UniRef50_A2FLX7 Cluster: AGC family protein kinase; n=4;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 469
Score = 230 bits (563), Expect = 4e-59
Identities = 120/316 (37%), Positives = 179/316 (56%), Gaps = 6/316 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
KS S+ ++DF+ KVLG G++G V LVKH T + YAMK + K + + + E+
Sbjct: 136 KSASDVSVDDFDILKVLGKGSYGKVQLVKHKGTNQIYAMKSISKRLLGEYELVSRIITER 195
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L +N PF+V +Y F+ ++ VL ++ GGE+FS LR+ KF E A++Y A++
Sbjct: 196 DVLLKINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLREERKFVEERARYYIAELAH 255
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
A+ YLH+ + +RDLKPENIL D+ GYIK+TDFG K T T CGTPEYLAPE+
Sbjct: 256 AIGYLHSMGICHRDLKPENILFDKDGYIKLTDFGLVKEQMTKDATTTTFCGTPEYLAPEM 315
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ Y +VDWW+LG L +EM G PPF+ + +Y I+ P + + D I
Sbjct: 316 VAGNAYDNNVDWWALGTLSYEMLYGVPPFYDVNTNAMYRSILRDDIVFPEDATEDAIDFI 375
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+L + T R G+ + + HK+F I++D +L +I + P+I S T+
Sbjct: 376 QKLLDKNPTTRLGSGPEDYKEVIGHKFFASINFDQLLKKQIPMQWKPQISS---NTDVSA 432
Query: 346 FDEEKIKDSPVCLYEE 361
FD E + P YE+
Sbjct: 433 FDREFTTEKPKLTYED 448
>UniRef50_Q16513 Cluster: Serine/threonine-protein kinase N2; n=42;
Eumetazoa|Rep: Serine/threonine-protein kinase N2 - Homo
sapiens (Human)
Length = 984
Score = 230 bits (563), Expect = 4e-59
Identities = 119/307 (38%), Positives = 177/307 (57%), Gaps = 10/307 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF VLG G FG V L ++ T + +A+K L+K IV +++ EK+I +N
Sbjct: 654 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 713
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+L L+Y
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 772
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSK 229
LH ++VYRDLK +N+L+D G++KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 832
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW LGVL++EM G PF D +++ IV + R P S E I+ +L
Sbjct: 833 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 892
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ + RR G + D K H +FR IDW ++++ ++ PPF P IR D +N FD+E
Sbjct: 893 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSN---FDDE 949
Query: 350 KIKDSPV 356
++P+
Sbjct: 950 FTSEAPI 956
>UniRef50_Q05655 Cluster: Protein kinase C delta type; n=61;
Eumetazoa|Rep: Protein kinase C delta type - Homo
sapiens (Human)
Length = 676
Score = 230 bits (563), Expect = 4e-59
Identities = 116/303 (38%), Positives = 179/303 (59%), Gaps = 10/303 (3%)
Query: 46 WDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSY 105
W+ S+ N +N+F KVLG G+FG V L + G+Y A+K L+K+ ++ +E +
Sbjct: 338 WEGSSKCN--INNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTM 395
Query: 106 YEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGA 164
EK++L PF+ ++ F+ +L++V+ F+ GG++ H++ G+FE A FY A
Sbjct: 396 VEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAA 455
Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYL 221
+++ L++LH+ ++YRDLK +N+L+DR G+IKI DFG CK R T CGTP+Y+
Sbjct: 456 EIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYI 515
Query: 222 APEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVEL 281
APEI+ Y SVDWWS GVLL+EM G PF D ++E I P + E
Sbjct: 516 APEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKES 575
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
KDI+ + + + T+R G + K H +F+ I+W + R+ PPF PK++SP D +
Sbjct: 576 KDILEKLFEREPTKRLGMTG----NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYS 631
Query: 342 NFD 344
NFD
Sbjct: 632 NFD 634
>UniRef50_O96997 Cluster: Protein kinase C; n=2;
Tetractinomorpha|Rep: Protein kinase C - Geodia cydonium
(Sponge)
Length = 677
Score = 230 bits (562), Expect = 5e-59
Identities = 113/307 (36%), Positives = 187/307 (60%), Gaps = 6/307 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L +F+ VLG G+FG VFL +H + + YA+K L+K+ IV+ +E + E+K+L +
Sbjct: 344 LGEFKLIVVLGKGSFGKVFLAEHKESKEVYAIKSLKKDLIVQEDDVECTLNERKVLALQS 403
Query: 116 FP-FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
P F++ + F+ +L++V+ +++GG++ H+ ++G+F E+ +FY A+++L L YLH
Sbjct: 404 KPPFLINLHSCFQTEEHLFFVMEYVSGGDLMFHILELGRFSESQTRFYAAEIVLGLVYLH 463
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK-LIRG--RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G++KI DFG CK I G + T CGTP+Y+APEII Y
Sbjct: 464 NLGIIYRDLKLDNVLLDSEGHVKIADFGLCKDGISGTSKARTFCGTPDYIAPEIIQYHPY 523
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
+VDWW+LGVL++EM G PPF D +++ IV + P S + II +L
Sbjct: 524 DAAVDWWALGVLIYEMLVGRPPFDGDDDDQLFMNIVQKQVHYPRGLSEPCRKIISGLLTK 583
Query: 292 DTTRRYGTLKDGVLD-FKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
+ ++R G+ + +D K +F+ +DW+ + + PP+ PK + + NFD F +E
Sbjct: 584 NASKRLGSHPEAGVDMIKAQPFFKNMDWEKLARREVKPPYRPKNKGKKNRDNFDPEFTKE 643
Query: 350 KIKDSPV 356
+ SPV
Sbjct: 644 PCRLSPV 650
>UniRef50_P90980 Cluster: Protein kinase C-like 2; n=49;
Eumetazoa|Rep: Protein kinase C-like 2 - Caenorhabditis
elegans
Length = 682
Score = 230 bits (562), Expect = 5e-59
Identities = 121/297 (40%), Positives = 178/297 (59%), Gaps = 7/297 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
K +DF VLG G+FG V L + T + +A+K+L+K+ I++ +E + EK++L
Sbjct: 344 KASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECTMTEKRVLALP 403
Query: 115 NFP-FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
P F+V + F+ LY+V+ F+ GG++ ++++GKF+E A FY A++ + L +L
Sbjct: 404 EKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFL 463
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK-LIRG--RTWTLCGTPEYLAPEIILSKG 230
H+ ++YRDLK +N++++R G+IKITDFG CK I G T T CGTP+Y+APEIIL +
Sbjct: 464 HSKGIIYRDLKLDNVMLERDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILYQP 523
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
YG SVDWW+ GVLLFEM AG PPF D ++ I P S E + +L
Sbjct: 524 YGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSLSKEAVSLCKALLI 583
Query: 291 VDTTRRYGTLKD---GVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ ++R G D D K H +FR IDW I +I PPF PK+++ T NFD
Sbjct: 584 KNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTENFD 640
>UniRef50_UPI00006CC8B4 Cluster: Protein kinase domain containing
protein; n=2; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 464
Score = 229 bits (559), Expect = 1e-58
Identities = 116/306 (37%), Positives = 180/306 (58%), Gaps = 11/306 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYY-EKKILCGL 114
L FE V+G G FG V LVK +GK +AMK+++K I+R +Q H EK IL
Sbjct: 37 LQSFELLNVIGEGKFGTVLLVKKKDSGKLFAMKIIKKS-IIRKRQFAHRIIQEKDILAFC 95
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
N F+ + Y F++ L+ +L + +GG++F+++ K E AKFY AQ++L LEYLH
Sbjct: 96 NNNFMTKLHYSFQNQNNLFLILDYCSGGDLFNYISKKNTISEKDAKFYAAQIVLMLEYLH 155
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTWTLCGTPEYLAPEIILSKGYG 232
+ +VYRDLKPENILI++ GY+K+ DFG+ + + ++CGTP Y PE+I +G+G
Sbjct: 156 SQNIVYRDLKPENILIEKNGYLKLGDFGYARQNMDSIEAKSVCGTPHYFPPEMITREGHG 215
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKI----VAGKYRCPSHFSVELKDIIGHV 288
VDWW+LG +++EM G PF S+ ++++I V + S KDI+ +
Sbjct: 216 KPVDWWALGCVIYEMVFGATPFDDSNQKILFDRIKNSPVIFENDKNKKVSNNFKDIVNKL 275
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FD 347
L+ + R GT + + K+H WF ++DW ++ N I PF P ++ D +NFD+ F
Sbjct: 276 LKKNQNERLGTA--SIEEIKSHPWFDKMDWTALSNQTIAAPFIPAVKKVSDVSNFDITFT 333
Query: 348 EEKIKD 353
+ + D
Sbjct: 334 NKDVSD 339
>UniRef50_UPI00006CB393 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 538
Score = 228 bits (558), Expect = 2e-58
Identities = 99/211 (46%), Positives = 140/211 (66%), Gaps = 3/211 (1%)
Query: 156 ETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLC 215
ET +++ + EYLH +VYRDLKPENILI GY+K+TDFGF K RT+TLC
Sbjct: 331 ETKKRYFKVSMF---EYLHNKNIVYRDLKPENILIGSDGYLKLTDFGFAKYCDSRTYTLC 387
Query: 216 GTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPS 275
GTPEYLAPEI+L+KG+G VDWW LG+L++EM AG PF DPM IY+KI+ GK + P
Sbjct: 388 GTPEYLAPEILLNKGHGKPVDWWCLGILIYEMLAGIDPFNDEDPMAIYQKILKGKVKFPR 447
Query: 276 HFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIR 335
+F K ++ H+L D T+RYG LK GV D K H+WF ++DWD++ + +I P + P ++
Sbjct: 448 NFDKNAKSLVKHLLVADLTKRYGNLKGGVNDIKTHRWFADMDWDALFHKKIPPTYKPVVK 507
Query: 336 SPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
GDT+N+ + + P+ ++ F ++
Sbjct: 508 GKGDTSNYSSYPDSTELPKPIKPADDPFINW 538
Score = 94.3 bits (224), Expect = 4e-18
Identities = 51/135 (37%), Positives = 81/135 (60%), Gaps = 17/135 (12%)
Query: 60 ERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFV 119
++Q+ + +FG V L K TG+Y A+KML+K +I+RLKQ++H E IL +N PF+
Sbjct: 140 KQQQSINRCSFGRVRLAKQKSTGEYVALKMLKKAEILRLKQVDHIISENTILSNINHPFL 199
Query: 120 VYMKYYF------------KDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
V + ++ +D+ +LY+VL ++AGGE+F++LR GK + A FY AQV
Sbjct: 200 VNLSTFYLHQQVIKMIGFTQDDRFLYFVLEYVAGGELFTYLRNKGKLDNPEALFYAAQV- 258
Query: 168 LALEYLHACELVYRD 182
Y+ C+L+ D
Sbjct: 259 ----YIFVCDLLSYD 269
>UniRef50_UPI00006607B3 Cluster: RAC-beta serine/threonine-protein
kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase
Akt-2) (Protein kinase B, beta) (PKB beta).; n=1;
Takifugu rubripes|Rep: RAC-beta serine/threonine-protein
kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase
Akt-2) (Protein kinase B, beta) (PKB beta). - Takifugu
rubripes
Length = 518
Score = 228 bits (557), Expect = 2e-58
Identities = 125/337 (37%), Positives = 185/337 (54%), Gaps = 41/337 (12%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K + +NDFE K+LG G FG V LVK TG +YAMK+L KE I+ ++ H+ E
Sbjct: 141 KGCARVTMNDFEYLKLLGKGTFGKVILVKEKATGVHYAMKILRKEVIIAKDEVAHTVTES 200
Query: 109 KILCGLNFPFVVY-------------------------MKYYFKDNVYLYYVLPFIAGGE 143
++L PF+ +KY F+ + L +V+ + GGE
Sbjct: 201 RVLQNTRHPFLTVRTLIMRQHLRQTHPPCDMIFLPPQTLKYAFQTHDRLCFVMEYANGGE 260
Query: 144 -------------MFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILI 190
+F H+ + F E A+FYGA+++ ALEYLH+ ++VYRDLK EN+++
Sbjct: 261 VRPPAPYLSICFQLFFHMSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDLKLENLML 320
Query: 191 DRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEM 247
D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG +VDWW LGV+++EM
Sbjct: 321 DKDGHIKITDFGLCKEGITPDATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEM 380
Query: 248 SAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDF 307
G PF+ D R++E I+ + R P + S E K ++ +L+ D +R G D +
Sbjct: 381 MCGRLPFYNQDHERLFELILMEEIRFPRNLSPEAKSLLAGLLKKDPKQRLGGGPDDAKEV 440
Query: 308 KNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
HK+F I+W ++ ++ P F P++ S DT FD
Sbjct: 441 MTHKFFTNINWQDVVQKKLTPLFKPQVTSETDTRYFD 477
>UniRef50_A0CNT4 Cluster: Chromosome undetermined scaffold_22, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_22,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 362
Score = 228 bits (557), Expect = 2e-58
Identities = 117/312 (37%), Positives = 177/312 (56%), Gaps = 10/312 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++ F V+G G+ G V LV+ K YA+K+++K K++ ++ + E+ IL
Sbjct: 31 IDQFHLLSVIGKGSIGKVVLVRKKDNQKIYALKVIKKTKLIENHSVKQIFAERNILQNCQ 90
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ ++Y F++ LY+ L + GGE++ L + K E AKFY +Q+ILA +YLH
Sbjct: 91 HPFIIKLEYAFQNETKLYFCLQYCPGGELYQLLVQKNKLTEEQAKFYASQIILAFQYLHE 150
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGR--TWTLCGTPEYLAPEIILSKGYG 232
+++YRDLKPEN+LID+ GYIK+TDFGF K I+G + CGT EYLAPE +L+ +G
Sbjct: 151 QDIIYRDLKPENVLIDQEGYIKLTDFGFSKQGIQGNFGAHSKCGTAEYLAPE-LLAGNHG 209
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPS-HFSVELKDIIGHVLQV 291
+ DWW+ G L++EM G P FF ++ +I+ + S + KD++ +LQ
Sbjct: 210 KAADWWTFGTLIYEMVIGQPAFFGETKEELFNQILHHEINYKKIGASSQFKDLLSKLLQK 269
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF-DVFDEEK 350
D R + + K H WF+ IDWD IL ++ P F P + S D F D F +E
Sbjct: 270 DPNNRISSAN----EIKKHPWFKNIDWDMILKRQMPPVFIPILNSDDDVQYFDDCFLKEP 325
Query: 351 IKDSPVCLYEEE 362
I L EE
Sbjct: 326 INSQTNSLSLEE 337
>UniRef50_A6QRT1 Cluster: Serine/threonine-protein kinase psk1; n=1;
Ajellomyces capsulatus NAm1|Rep:
Serine/threonine-protein kinase psk1 - Ajellomyces
capsulatus NAm1
Length = 1007
Score = 228 bits (557), Expect = 2e-58
Identities = 120/293 (40%), Positives = 171/293 (58%), Gaps = 7/293 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI-VRLKQIEHSYYEKKILCGLN- 115
DFE+ LG G +G V LV+H +TG YA K K + V K +E + E+ IL +N
Sbjct: 645 DFEQLSCLGKGTYGTVLLVRHTMTGVLYAQKQFRKASLTVHRKLVEQTKTERAILESVNR 704
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PFVV + Y F+D+ LY +L + GGE+F+HL F E A FY A+++LALE+LH
Sbjct: 705 HPFVVKLYYAFQDHEKLYLILEYAQGGELFTHLAMERMFSEEVASFYMAELVLALEHLHN 764
Query: 176 -CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKGY 231
+VYRDLKPEN L+D G++ +TDFG K+ + R + GT EY+APE++ K Y
Sbjct: 765 NVGVVYRDLKPENCLLDADGHLLLTDFGLSKVAVDGQDRCNSSLGTVEYMAPEVVQGKPY 824
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G + DWWSLG L F++ G PPF A++ +I EKIV K P + KD++ +L+
Sbjct: 825 GKACDWWSLGALGFDLLTGSPPFKANNHAKIQEKIVKQKLVLPYFLGPDAKDLLTRLLRK 884
Query: 292 DTTRRYG-TLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ +R G + + K H++FR+IDW S+ + PP P I P NF
Sbjct: 885 EPHKRLGYHMPKDIQTIKKHRFFRKIDWKSLERRELEPPIKPLITDPALAENF 937
>UniRef50_Q4N4B2 Cluster: CAMP-dependent protein kinase catalytic
subunit, putative; n=2; Theileria|Rep: CAMP-dependent
protein kinase catalytic subunit, putative - Theileria
parva
Length = 511
Score = 227 bits (556), Expect = 3e-58
Identities = 112/267 (41%), Positives = 169/267 (63%), Gaps = 4/267 (1%)
Query: 83 KYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
K ++K+L K KI+ +Q+EH EK IL L PF+V F+D + LY++L F+ GG
Sbjct: 228 KIVSLKILSKNKIIEKRQLEHVKNEKNILSTLKHPFIVGYLGSFQDTLNLYFILEFVPGG 287
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
E+F++LR+M F +FY +QV+LAL+YLH +LVYRDLKPENIL+D GYI++ DFG
Sbjct: 288 ELFTYLRRMHTFPPEYTRFYASQVLLALDYLHMNKLVYRDLKPENILLDIMGYIRLVDFG 347
Query: 203 FCK-LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMR 261
F K L G+T+T+CGT +YLAPEI L KG+ D++S GV L+E+ G PPF+++ P +
Sbjct: 348 FAKRLESGKTYTVCGTCDYLAPEIFLKKGHDFRADFYSFGVFLYELLTGVPPFYSNSPQK 407
Query: 262 IYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSI 321
Y+ + + + +DII ++L+VD ++R G + V + H +F ID++ +
Sbjct: 408 TYKLALNNEVAFGRKVNNVSRDIIKNLLRVDPSKRLG---NNVKEVYFHPFFDGIDFNML 464
Query: 322 LNSRIHPPFFPKIRSPGDTTNFDVFDE 348
L +I P P + S D +NF + E
Sbjct: 465 LAKQIKAPIVPSVSSHDDVSNFIKYPE 491
>UniRef50_O42632 Cluster: Protein kinase C-like; n=14; Fungi|Rep:
Protein kinase C-like - Cochliobolus heterostrophus
(Drechslera maydis)
Length = 1174
Score = 227 bits (556), Expect = 3e-58
Identities = 113/295 (38%), Positives = 175/295 (59%), Gaps = 7/295 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+ F VLG G FG V L + T + YA+K+L+KE I+ ++E + EK++ N
Sbjct: 846 LDHFNFLAVLGKGNFGKVMLAETKTTKQLYAIKVLKKEFIIENDEVESTRSEKRVFLIAN 905
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF++ + F+ +Y+V+ +I+GG++ H+++ G+F A+FY A+V LAL+Y
Sbjct: 906 KERHPFLLNLHACFQTETRVYFVMEYISGGDLMLHIQR-GQFGTKRAQFYAAEVCLALKY 964
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSK 229
H ++YRDLK +NI++ G+IK+ D+G CK T T CGTPE++APEI+L K
Sbjct: 965 FHENGVIYRDLKLDNIMLTLDGHIKVADYGLCKEEMWYGSTTSTFCGTPEFMAPEILLDK 1024
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
YG +VDWW+ GVL+++M PF D IY+ I+A + P H + I+ +L
Sbjct: 1025 KYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLL 1084
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ R G+ + +H +FR I+WD I + R+ PPF P+I SP DT+NFD
Sbjct: 1085 TREPEMRLGSGPTDAQEIMSHAFFRNINWDDIYHKRVQPPFIPQITSPTDTSNFD 1139
>UniRef50_A0BJU7 Cluster: Chromosome undetermined scaffold_110,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_110,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 379
Score = 227 bits (554), Expect = 5e-58
Identities = 118/307 (38%), Positives = 179/307 (58%), Gaps = 11/307 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+ +F+ K +G G FG V LV+ +GK YAMK++ K+ + KQ+E++ E+ IL +N
Sbjct: 56 VTNFKLLKTIGRGNFGKVLLVRKRNSGKIYAMKIVNKQDLQVKKQVEYARTERIILEKIN 115
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ + Y F+ LYYV+ + AGGE+F HLR+ KF+E +FY ++I+ALEYLH
Sbjct: 116 HPFISKLHYAFQTQQKLYYVIDYCAGGELFFHLRRAYKFKENQVQFYAVEIIIALEYLHD 175
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTPEYLAPEIILSK--G 230
+++YRDLKPENIL+ G+IK+ DFG K+I R ++++ GTPEYLAPEI G
Sbjct: 176 SKILYRDLKPENILLCSDGHIKLIDFGLSKIISNRDKPSFSIVGTPEYLAPEIYSDDKLG 235
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ S DWWSLG LL+EM G PF++ D ++ + FS ++ +L
Sbjct: 236 HDESCDWWSLGALLYEMLTGAAPFYSQDRTMMFRNRTEKQIEMKPWFSEACSSLLTGLLN 295
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
+ +R + K H +F +IDW+ N ++ PP P++ D F+ +F +E
Sbjct: 296 NNPKQRI-----NIQQIKKHPFFSDIDWNQASNRQLIPPIIPELSDELDLRYFNKMFLDE 350
Query: 350 KIKDSPV 356
DSPV
Sbjct: 351 PAIDSPV 357
>UniRef50_Q00078 Cluster: Protein kinase C-like; n=8;
Eurotiomycetidae|Rep: Protein kinase C-like - Aspergillus
niger
Length = 1096
Score = 226 bits (552), Expect = 8e-58
Identities = 113/295 (38%), Positives = 176/295 (59%), Gaps = 7/295 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+ F VLG G FG V L + T + YA+K+L+KE I+ ++E + EK++ N
Sbjct: 768 LDHFNFLAVLGKGNFGKVMLAETKSTKRLYAIKVLKKEFIIENDEVESTKSEKRVFMIAN 827
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF++ + F+ +Y+V+ +I+GG++ H+++ G+F A+FY A+V+LAL+Y
Sbjct: 828 KERHPFLLNLHACFQTETRVYFVMEYISGGDLMLHIQR-GQFGLKRAQFYAAEVLLALKY 886
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSK 229
H ++YRDLK +NI++ G+IK+ D+G CK T T CGTPE++APEI+L K
Sbjct: 887 FHENGVIYRDLKLDNIMLTLDGHIKVADYGLCKENMWYGATTSTFCGTPEFMAPEILLDK 946
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
YG +VDWW+ GVL+++M PF D IY+ I+A + P H + I+ +L
Sbjct: 947 RYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLL 1006
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ R G+ + +H +FR I+WD I + R+ PPF P+I SP DT+NFD
Sbjct: 1007 TREPELRLGSGPTDAQEVMSHAFFRNINWDDIYHKRVPPPFLPQISSPTDTSNFD 1061
>UniRef50_Q6C292 Cluster: Similar to sp|P24583 Saccharomyces
cerevisiae YBL105c PKC1 ser/thr protein kinase; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P24583
Saccharomyces cerevisiae YBL105c PKC1 ser/thr protein
kinase - Yarrowia lipolytica (Candida lipolytica)
Length = 1252
Score = 225 bits (551), Expect = 1e-57
Identities = 113/302 (37%), Positives = 179/302 (59%), Gaps = 6/302 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K L+DF VLG G FG V L + T YA+K+L+K+ I+ ++E + E+
Sbjct: 915 KKRPRIGLDDFNFLAVLGKGNFGKVMLAESKKTTNLYAIKVLKKDFIIENDEVESTRSER 974
Query: 109 KILCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
++ N PF++ + F+ +Y+V+ +++GG++ H++K G F+ A+FY A+
Sbjct: 975 RVFQIANRESHPFLLNLYSCFQTENRVYFVMDYVSGGDLMWHIQKEGVFKPGRAQFYAAE 1034
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLA 222
V+L +++ H ++YRDLK +NIL+ R G++KI D+G CK + GRT T CGTPE++A
Sbjct: 1035 VLLGIKHFHDNGVIYRDLKLDNILLTRDGHVKIADYGLCKEDMDYGRTTGTFCGTPEFMA 1094
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PEI+L + YG++VDWW+ GVL+++M G PF D I++ I+A + R P
Sbjct: 1095 PEILLEQRYGLAVDWWAFGVLIYQMVLGQSPFRGEDEDEIFDAILADEPRYPITLPGNCV 1154
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
I+ +L + RR G+ + H +F +++D I + RI PPF PKI SP D TN
Sbjct: 1155 SILTQLLTREPERRLGSGPRDAEEIMAHPYFANVNFDDIYHKRIPPPFVPKITSPTDVTN 1214
Query: 343 FD 344
FD
Sbjct: 1215 FD 1216
>UniRef50_P13677 Cluster: Protein kinase C, eye isozyme (EC
2.7.11.13) (PKC) (dPKC53E(EY)); n=5; Eumetazoa|Rep:
Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)
(dPKC53E(EY)) - Drosophila melanogaster (Fruit fly)
Length = 700
Score = 225 bits (551), Expect = 1e-57
Identities = 119/303 (39%), Positives = 169/303 (55%), Gaps = 5/303 (1%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNF 116
DF KV+G G+FG V L + T + YA+K+L K+ I++ +E EKKIL
Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRP 429
Query: 117 PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHAC 176
PF+V M F+ L++V+ + GG++ H+++ G+F+E+ A FY +V +AL +LH
Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHER 489
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKGYGM 233
+++YRDLK +NIL+D G++K+ DFG K R T T CGTP Y+APEI+ Y +
Sbjct: 490 DIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSI 549
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
+ DWWS GVLLFE AG PF D ++ I K P HFSVE DII L
Sbjct: 550 AADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKP 609
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF-DVFDEEKIK 352
R G + + H +FR +DWD + PP P I+ D +NF D F +EK
Sbjct: 610 NNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTD 669
Query: 353 DSP 355
+P
Sbjct: 670 LTP 672
>UniRef50_Q16QY2 Cluster: Ribosomal protein S6 kinase, 90kD,
polypeptide; n=1; Aedes aegypti|Rep: Ribosomal protein
S6 kinase, 90kD, polypeptide - Aedes aegypti
(Yellowfever mosquito)
Length = 1037
Score = 225 bits (550), Expect = 1e-57
Identities = 126/319 (39%), Positives = 184/319 (57%), Gaps = 14/319 (4%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKH---IVTGKYYAMKMLEKEKIVRLKQI-EHSYY 106
+ ++DF+ KVLGTGA+G VFLV+ + K YAMK+L+K I + K+ EH+
Sbjct: 21 DDKVSMDDFKLLKVLGTGAYGKVFLVRKLGGVDNNKLYAMKVLKKATICQKKKTAEHTRT 80
Query: 107 EKKILCGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+++L + PF+V M Y F+ L+ +L +++GGE+F+HL F E + Y A+
Sbjct: 81 ERQVLESIKRSPFLVTMHYAFQTESKLHIILDYVSGGELFTHLYNKEHFTEDEVRIYIAE 140
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+I+ALE LH ++YRD+K ENILID G+I +TDFG + + R + CGT EY+A
Sbjct: 141 IIVALEQLHKLGIIYRDIKLENILIDSEGHIVLTDFGLSRELVYENERAHSFCGTIEYMA 200
Query: 223 PEIILS--KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPM---RIYEKIVAGKYRCPSHF 277
PEI+ S G+ +VDWWS+GVL FE+ G PF + + + I +KI + P H
Sbjct: 201 PEIVKSNQNGHDQTVDWWSVGVLTFELLTGSSPFSSEESVTQTEISKKITNTEAVIPDHL 260
Query: 278 SVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSP 337
S E KD I +L D RR G + K+H +F+ I+W + + +I PF P I
Sbjct: 261 SREAKDFIRKLLVKDPRRRLGGGSADASELKSHDFFKSINWRQLADKKISAPFRPVIEDE 320
Query: 338 GDTTNF-DVFDEEKIKDSP 355
DT NF D F + DSP
Sbjct: 321 LDTNNFSDEFTRQTPVDSP 339
Score = 107 bits (257), Expect = 5e-22
Identities = 78/268 (29%), Positives = 127/268 (47%), Gaps = 29/268 (10%)
Query: 54 AKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG 113
+K + + +G G F + + + KYYA+K+L + E++ E + L
Sbjct: 389 SKRYELSSDRAIGDGLFSTCLKCRRLSSSKYYAVKVLFNHP----EPAEYARREVEALKE 444
Query: 114 LN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
P +V KD+ ++Y VL + GGE+ + K F ++ A+ Y Q++ A+ Y
Sbjct: 445 CQGHPNIVKFVEVLKDSHHIYIVLELLGGGELLHRINKTSSFTDSQARHYFRQMVQAVAY 504
Query: 173 LHACELVYRDLKPENILID--RTGYIKITDFGFCKLIRGR----TWTLCGTPEYLAPEII 226
+H + + DLKPEN+L + + ++K+ DF F K I + + GT Y APE+
Sbjct: 505 MHQKGIAHCDLKPENVLFEGPSSEHLKLIDFSFAKSIENNNCLVSSPIAGTLGYSAPEVF 564
Query: 227 LSKGYGM-SVDWWSLGVLLFEMSAGHPPF----------FASDPMR---IYEKIVAGKYR 272
+ Y + S D WSLGV+L+ M G PF AS + I +KI G +
Sbjct: 565 DGRSYALESSDLWSLGVILYTMLCGQAPFTPRQFFGHTNLASSAKQMEIIMDKIRRGSFD 624
Query: 273 CPSH----FSVELKDIIGHVLQVDTTRR 296
+ S E KD++ +L VD RR
Sbjct: 625 LAASAWECVSEEAKDLVKRLLTVDPDRR 652
>UniRef50_A1Z7T1 Cluster: CG2049-PC, isoform C; n=7; Fungi/Metazoa
group|Rep: CG2049-PC, isoform C - Drosophila melanogaster
(Fruit fly)
Length = 1407
Score = 225 bits (550), Expect = 1e-57
Identities = 118/307 (38%), Positives = 174/307 (56%), Gaps = 8/307 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL---C 112
+++F VLG G FG V L + +YYA+K L+K I+ ++E EK+I
Sbjct: 1077 MDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVAN 1136
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
+ PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+L L+Y
Sbjct: 1137 AMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHT-DVFLEPRAVFYAACVVLGLQY 1195
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSK 229
LH +++YRDLK +N+L+D GY+KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 1196 LHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTET 1255
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW LGVL+FEM G PF D +++ IV + R P S+E ++ +L
Sbjct: 1256 SYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLL 1315
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDE 348
+ + RR G+ + D K +FR I WD +L ++ PPF P I D +NFD F
Sbjct: 1316 RKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFTS 1375
Query: 349 EKIKDSP 355
EK + +P
Sbjct: 1376 EKAQLTP 1382
>UniRef50_A0DVL2 Cluster: Chromosome undetermined scaffold_66, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_66,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 488
Score = 225 bits (550), Expect = 1e-57
Identities = 115/291 (39%), Positives = 178/291 (61%), Gaps = 6/291 (2%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYY-EKK 109
+S L DF K +G G F V+LVK + ++YAMK+++K KI+ K+IE+ E+
Sbjct: 121 KSKTGLRDFIFIKCIGVGGFSRVYLVKKKQSSRFYAMKIIDK-KIIIEKKIENIIENERN 179
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PF+ ++Y + +L ++ F AGG++ +L+K F ET A+FY + IL
Sbjct: 180 ILAVTQHPFLNKLEYALECPNHLIFITEFCAGGDLLYYLQKYHVFTETQARFYIIEFILG 239
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR-TWTLCGTPEYLAPEIILS 228
L YLH +++YRD+KPENILID TG+I+I DFG K R ++ CG+PEY+APE++ +
Sbjct: 240 LIYLHQLDIIYRDIKPENILIDITGHIQIADFGLAKPTRNEYAYSFCGSPEYMAPEMLTN 299
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH--FSVELKDIIG 286
+G+ +D + LGVLL+E+ G PPF++ D +IYE I+ + P + S E+KD+I
Sbjct: 300 QGHNQQLDHYCLGVLLYELVVGQPPFYSEDINKIYENIILKEVEFPKNNTLSNEIKDLIV 359
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSP 337
+L D R G + G+L+ +HKWF +D L +++PPF P + P
Sbjct: 360 RLLDKDQKSRIGH-QGGLLEILDHKWFESVDLIKFLYRKVNPPFQPDVFKP 409
>UniRef50_Q6UB97 Cluster: Protein kinase C 1; n=7; Dikarya|Rep:
Protein kinase C 1 - Cryptococcus neoformans var. grubii
(Filobasidiella neoformans var.grubii)
Length = 1086
Score = 225 bits (550), Expect = 1e-57
Identities = 114/308 (37%), Positives = 183/308 (59%), Gaps = 8/308 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL- 114
L+DF VLG G FG V L + + YA+K+L+KE I+ ++E + EK++
Sbjct: 754 LDDFNFLAVLGKGNFGKVMLAEEKTSSNLYAIKVLKKEFIIENDEVESTQSEKRVFLAAA 813
Query: 115 --NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF++ + F+ +Y+V+ +I+GG++ H++K +F AKFY +V+LAL+Y
Sbjct: 814 QERHPFLLGLHSCFQTETRVYFVMEYISGGDLMLHIQKK-QFTLRQAKFYACEVLLALQY 872
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSK 229
H+ ++YRDLK +NIL+ G++K+ D+G CK + G+T T CGTPE++APEI+L +
Sbjct: 873 FHSKGIIYRDLKLDNILLTLDGHVKVADYGLCKEEMWFGKTTSTFCGTPEFMAPEILLEQ 932
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
YG +VDWW+ GVL +EM G PF D I++ I+ + P + ++ +L
Sbjct: 933 RYGRAVDWWAFGVLTYEMLLGQSPFRGEDEDEIFDAILEDEPLYPITMPRDAVSLLQRLL 992
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDE 348
D TRR G + + K H +FR++++D + + RI PP+FP I + DT+NFD F
Sbjct: 993 TRDPTRRLGAGEGDAEEIKQHLFFRDVNFDDVYHKRIPPPYFPVIGNATDTSNFDQEFTR 1052
Query: 349 EKIKDSPV 356
E+ +PV
Sbjct: 1053 EQPTLTPV 1060
>UniRef50_A6RHI7 Cluster: Serine/threonine-protein kinase Sgk2; n=1;
Ajellomyces capsulatus NAm1|Rep:
Serine/threonine-protein kinase Sgk2 - Ajellomyces
capsulatus NAm1
Length = 459
Score = 225 bits (550), Expect = 1e-57
Identities = 109/251 (43%), Positives = 156/251 (62%), Gaps = 7/251 (2%)
Query: 87 MKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFS 146
MK+L K I+ ++ H+ E+ +L +N PF+V +K+ F+ LY VL F+ GGE+F
Sbjct: 1 MKILRKTHIISRSEVAHTLAERSVLSQINNPFIVPLKFSFQSPEKLYLVLAFVNGGELFH 60
Query: 147 HLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL 206
HL++ +F+ A+FY A++I ALE LH +++YRDLKPENIL+D G+I + DFG CKL
Sbjct: 61 HLQREQRFDINRARFYTAELICALECLHGFKIIYRDLKPENILLDYAGHIALCDFGLCKL 120
Query: 207 ---IRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIY 263
RT T CGTPEYLAPE++L +GY +VDWW+LGVLL+EM G PPF+ + +Y
Sbjct: 121 DMKDEDRTNTFCGTPEYLAPELLLGEGYTKAVDWWTLGVLLYEMLTGLPPFYDENTNEMY 180
Query: 264 EKIVAGKYRCPSHFSV--ELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSI 321
KI+ PS V +D++ +L+ D RR G +G + K H +F IDW +
Sbjct: 181 RKILQEPLTFPSQDIVPGAARDLLTRLLEGDPNRRLGA--NGAAEIKAHHFFSNIDWRKL 238
Query: 322 LNSRIHPPFFP 332
L + P F P
Sbjct: 239 LQRKYEPSFRP 249
>UniRef50_UPI00004999BB Cluster: protein kinase; n=3; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 420
Score = 224 bits (548), Expect = 2e-57
Identities = 120/316 (37%), Positives = 184/316 (58%), Gaps = 33/316 (10%)
Query: 40 QDFVESWDDKSE--SNA---KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEK 94
Q F++ KS+ SNA KL DFE K++G G +G K+
Sbjct: 94 QKFIDEKCSKSDQSSNALKPKLEDFETLKLIGKGTYG--------------------KKA 133
Query: 95 IVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKF 154
+V ++EH+ E+++L ++ PF+V+M Y F+ LY+V+ FI GGE+F HL+ +F
Sbjct: 134 VVETNEVEHTMAEREVLGTIDNPFIVHMHYSFQTENKLYFVMDFINGGELFYHLQNERRF 193
Query: 155 EETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGR--- 210
AKFY A+++LALE+LH ++YRDLKPEN+L++ G++ ITDFG K ++G
Sbjct: 194 SIARAKFYAAEILLALEHLHLHGIIYRDLKPENVLLNADGHVCITDFGLSKTGMKGEGDM 253
Query: 211 TWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK 270
T T CGT YLAPEI+L + Y +VDWWS G+L +EM G PPF++ D +Y+ IV
Sbjct: 254 TSTFCGTAAYLAPEILLGEKYDSAVDWWSFGILTYEMMVGIPPFYSEDEREMYQNIVNEA 313
Query: 271 YRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPF 330
R P + +K I +L+ + TRR L D + K+H +F+ +D+D ++ + PP+
Sbjct: 314 VRYPPNTPSSIKTFIDALLEKNPTRR---LTDTTI-MKHHPFFQGLDFDRLMKKEVVPPY 369
Query: 331 FPKIRSPGDTTNFDVF 346
P++ S D N D +
Sbjct: 370 IPQVHSADDVANIDPY 385
>UniRef50_A0DZB2 Cluster: Chromosome undetermined scaffold_7, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_7,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 379
Score = 224 bits (548), Expect = 2e-57
Identities = 111/312 (35%), Positives = 174/312 (55%), Gaps = 4/312 (1%)
Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107
D+ L+ F + LG G++G V LV+H V+ K YAMK+L K+ + L Q +H E
Sbjct: 39 DEDGEKISLSHFIMLRNLGKGSYGKVMLVQHTVSLKLYAMKVLIKKSVKTLTQKKHVQTE 98
Query: 108 KKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
+K+L N F+ + Y F+ LY ++ F+ GGE+F HL+ G+ E KFY A+++
Sbjct: 99 RKVLEITNHNFITKLHYAFQSQTKLYLIMEFVPGGELFYHLKLQGRMTEKKTKFYAAEIL 158
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW---TLCGTPEYLAPE 224
+ L+YLH ++YRDLKPENIL+D G+IK+ DFG K+ G T+CGT EY+APE
Sbjct: 159 IGLDYLHKQNIIYRDLKPENILLDSEGHIKLCDFGLSKICYGNDMSAKTVCGTIEYIAPE 218
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
+I+ + Y DWW+ G LL+++ G PPF+ +I E P + S E D+
Sbjct: 219 VIIGQVYSKCCDWWTYGALLYDLLTGKPPFYRLSRKQIIEYATEKDIEIPQYLSEEATDL 278
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ + R G LK + H +F+++D+ I I PP + P + +
Sbjct: 279 LKKLLKRNPRERLG-LKRDAQEIYEHPFFKDVDFKKIGRKEIAPPVEMQNERPFKFFDQN 337
Query: 345 VFDEEKIKDSPV 356
+ + +KD+PV
Sbjct: 338 LIRKCSVKDTPV 349
>UniRef50_Q7PRV3 Cluster: ENSANGP00000020017; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020017 - Anopheles gambiae
str. PEST
Length = 613
Score = 224 bits (547), Expect = 3e-57
Identities = 111/308 (36%), Positives = 181/308 (58%), Gaps = 7/308 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GL 114
++DF VLG G+FG VFL + + YYA+K L+K+ ++ ++ + E+K+L G
Sbjct: 290 VDDFHFLTVLGKGSFGKVFLAELKNSDYYYAIKCLKKDVVLEDDDVDCTLIERKVLALGT 349
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF+ ++ F+ + +L++V+ ++ GG++ H+++ G+F E A+FY A+++ L++LH
Sbjct: 350 KHPFLCHLFCTFQTDSHLFFVMEYLNGGDLMFHIQQSGRFPEARARFYAAEIVSGLKFLH 409
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEIILSKGY 231
+VYRDLK +N+L+D G+++I DFG CKL + + CGTP+Y+APEII + Y
Sbjct: 410 RKGIVYRDLKLDNVLLDYDGHVRIADFGMCKLEIYLDKLADSFCGTPDYMAPEIIKGQKY 469
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
+VDWWS GVL++EM G PF D ++ I P + S E ++ +L+
Sbjct: 470 NQAVDWWSFGVLVYEMLVGQSPFSGCDEDELFWSICNEIPWFPHYLSKEALRLLQSLLEK 529
Query: 292 DTTRRYGTLK--DGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDE 348
D + R G L D D K H +F I WD + + PPF P++R P DT FD F
Sbjct: 530 DASIRLGVLNTMDEESDIKYHPFFNSIIWDKLERRAVEPPFKPQVRHPLDTQYFDKQFTR 589
Query: 349 EKIKDSPV 356
E+ + +P+
Sbjct: 590 ERARLTPI 597
>UniRef50_A2DL59 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 436
Score = 223 bits (546), Expect = 4e-57
Identities = 121/347 (34%), Positives = 185/347 (53%), Gaps = 17/347 (4%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG 82
+S E +++ +R F +S ++ F+ VLG GAFG V LV+H +
Sbjct: 89 FSTDTSENVQKWITGIRSSF------ESSPVLSMSSFDILHVLGRGAFGKVMLVRHRSSM 142
Query: 83 KYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
K YA+K ++K K++ + E+ IL + PF+V + + F++ Y L ++ GG
Sbjct: 143 KLYAIKSIQKRKLLDAMKSHTVIAERNILMKAHHPFIVQLFFAFQNPSKFYLGLEYVPGG 202
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
E+F HL K G F + Y A++ LAL YLH+ ++YRDLKPEN+++D TG+IK+TDFG
Sbjct: 203 ELFYHLTKRGTFPINEVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFG 262
Query: 203 FCKLI---RGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDP 259
+ + CGT YL+PE+I Y +DWWSLG+L++EM GHPPF + +
Sbjct: 263 LSTEVFELEECGDSFCGTSRYLSPEMIYKIKYTHKIDWWSLGILMYEMIVGHPPFDSQNR 322
Query: 260 MRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWD 319
++Y I PS F V+ KD++ +L + +R K+H +F+ IDWD
Sbjct: 323 SQLYNDITHSDPVFPSSFPVDAKDLVCKLLTKNPNQR-----PDFSGIKDHVFFKGIDWD 377
Query: 320 SILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
+ N P F PK +P + VF +E DS V +F DF
Sbjct: 378 KVYNREYQPNFIPKQTTPNCDS---VFLQESPADSIVTATSAQFPDF 421
>UniRef50_Q86ZV2 Cluster: Protein kinase C; n=1; Pichia pastoris|Rep:
Protein kinase C - Pichia pastoris (Yeast)
Length = 1035
Score = 223 bits (546), Expect = 4e-57
Identities = 114/308 (37%), Positives = 178/308 (57%), Gaps = 8/308 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+DF VLG G FG V L + I TG+ A+K+L+K+ I++ ++ + EK++ N
Sbjct: 706 LDDFRFIAVLGKGNFGKVMLAESIHTGQLCAIKVLKKDFIIKNDEVASTKSEKRVFIIAN 765
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF++ + F+ +Y+V+ +++GG++ H ++ F + AKFY A+V+LAL+Y
Sbjct: 766 RGKHPFLLNLHQCFQTENRIYFVMEYVSGGDLMWHAQQR-TFSPSRAKFYAAEVLLALQY 824
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSK 229
H +VYRDLK +NIL+ G+IK+ D+G CK T T CGTPE++APEI+ +
Sbjct: 825 FHENGVVYRDLKLDNILLTADGHIKLADYGLCKEEMWYGSTTATFCGTPEFMAPEILKEQ 884
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW+ GVLL++M G PF D ++ I+ + R P E DI+ +L
Sbjct: 885 KYDKAVDWWAFGVLLYQMMLGKSPFKGEDEDEVFNSILTDEPRYPIQMDRESVDILQQLL 944
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDE 348
D +R G ++ + K H +F I+WD I+ ++ PP P I+ D +NFDV F
Sbjct: 945 TKDPYKRLGASEEDAEEIKRHPYFHGINWDDIMQCKVPPPLIPTIKDRHDVSNFDVEFTT 1004
Query: 349 EKIKDSPV 356
E K +PV
Sbjct: 1005 EAPKLTPV 1012
>UniRef50_O62570 Cluster: Protein kinase C-related kinase; n=1;
Suberites domuncula|Rep: Protein kinase C-related kinase
- Suberites domuncula (Sponge)
Length = 1102
Score = 223 bits (544), Expect = 8e-57
Identities = 117/307 (38%), Positives = 177/307 (57%), Gaps = 10/307 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+D+ VLG G FG V + + T + A+K+L+K IV +++ EK+I +N
Sbjct: 770 LDDYAYMAVLGRGHFGKVLMAEDKKTKELVAIKVLKKGDIVARDEVDSLMSEKRIFETVN 829
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ ++ +V+ + GG++ H+ + F+E A FY A V+L L+Y
Sbjct: 830 SIRHPFLVNLHSCFQTEQHVCFVMEYACGGDLMMHIHQ-DIFKEPRACFYAACVVLGLQY 888
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEIILSK 229
LH +VYRDLK +N+L+D+ GY+KI DFG CK + G RT T CGTPE+LAPE++
Sbjct: 889 LHEKGIVYRDLKLDNLLLDKDGYVKIADFGLCKEGMWHGTRTSTFCGTPEFLAPEVLTDV 948
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW LGVL++EM G PF D +++ IV R P S E I+ +L
Sbjct: 949 SYTRAVDWWGLGVLIYEMLVGESPFPGEDEEEVFDSIVNDDVRYPRFLSSEAISIMRKLL 1008
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ + +R G + +D + +FR IDWD + + I PPF P +RS D +N FDEE
Sbjct: 1009 RRNPEKRLGASERDAMDIRKQPFFRHIDWDKLYHKDIQPPFKPVLRSRLDISN---FDEE 1065
Query: 350 KIKDSPV 356
++ P+
Sbjct: 1066 FTREDPI 1072
>UniRef50_A2DA20 Cluster: AGC family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 442
Score = 222 bits (543), Expect = 1e-56
Identities = 114/310 (36%), Positives = 177/310 (57%), Gaps = 12/310 (3%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
++ ++DF VLG G +G V LV+ T YA+K + K ++++ +++ + E+
Sbjct: 101 NDRTTTMDDFNIISVLGRGYYGKVMLVQKKGTKNLYAIKSIHKARLIQTRKVHTVFSERN 160
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL + PF+V + + F+ Y + +I GGE+F +L K+GK + + +FY A++ LA
Sbjct: 161 ILMKVKHPFIVSLSFAFQSMSKFYLGMQYIPGGELFRYLSKVGKLQMSEVRFYAAEIGLA 220
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTWTLCGTPEYLAPEIIL 227
L +LH+ ++YRDLKPENIL+D G+IK+TDFG K T T CGT EYLAPEI+
Sbjct: 221 LSHLHSNGIIYRDLKPENILLDEEGHIKLTDFGLAKDMSFDSATSTFCGTVEYLAPEIVR 280
Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGH 287
+ YGM++DWWS G L++E GH PF+ + +I+ +I A + PS F + D I
Sbjct: 281 REPYGMAIDWWSYGCLVYEFIFGHTPFYDENRAKIFMRIPADQPYYPSDFDPNVSDFINQ 340
Query: 288 VLQVD--TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+L D T + TLKD H ++ +D+D +L ++ P + P I + NFD
Sbjct: 341 LLSKDPETRATFDTLKD-------HPFWEGMDFDEVLERKVEPLYVPPIDDKFNPENFDS 393
Query: 345 VFDEEKIKDS 354
F E DS
Sbjct: 394 AFTRETPCDS 403
>UniRef50_Q16512 Cluster: Serine/threonine-protein kinase N1; n=26;
Euteleostomi|Rep: Serine/threonine-protein kinase N1 -
Homo sapiens (Human)
Length = 942
Score = 222 bits (543), Expect = 1e-56
Identities = 117/300 (39%), Positives = 172/300 (57%), Gaps = 7/300 (2%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+S L DF+ VLG G FG V L + +G+ +A+K L+K IV ++E EK+I
Sbjct: 607 KSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRI 666
Query: 111 LCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
L + PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+
Sbjct: 667 LAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVV 725
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPE 224
L L++LH ++VYRDLK +N+L+D GY+KI DFG CK G RT T CGTPE+LAPE
Sbjct: 726 LGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPE 785
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ Y +VDWW LGVLL+EM G PF D +++ IV + R P S E I
Sbjct: 786 VLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGI 845
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ + RR G+ + D K +FR + W+++L R+ PPF P + D +NFD
Sbjct: 846 MRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFD 905
>UniRef50_Q62074 Cluster: Protein kinase C iota type; n=26;
Eumetazoa|Rep: Protein kinase C iota type - Mus musculus
(Mouse)
Length = 586
Score = 222 bits (543), Expect = 1e-56
Identities = 123/348 (35%), Positives = 195/348 (56%), Gaps = 16/348 (4%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG 82
Y+P+ E Q ++ ++ K+ S+ L DF+ +V+G G++ V LV+ T
Sbjct: 209 YNPSSHESLDQVGEE-KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTD 267
Query: 83 KYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAG 141
+ YAMK+++KE + + I+ EK + N PF+V + F+ L++V+ ++ G
Sbjct: 268 RIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNG 327
Query: 142 GEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDF 201
G++ H+++ K E A+FY A++ LAL YLH ++YRDLK +N+L+D G+IK+TD+
Sbjct: 328 GDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDY 387
Query: 202 GFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF---- 254
G CK L G T T CGTP Y+APEI+ + YG SVDWW+LGVL+FEM AG PF
Sbjct: 388 GMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVG 447
Query: 255 FASDPMR-----IYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGT-LKDGVLDFK 308
+ +P + +++ I+ + R P SV+ ++ L D R G + G D +
Sbjct: 448 SSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQ 507
Query: 309 NHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSP 355
H +FR +DWD + ++ PPF P I NFD F E ++ +P
Sbjct: 508 GHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTP 555
>UniRef50_P41743 Cluster: Protein kinase C iota type; n=97;
Bilateria|Rep: Protein kinase C iota type - Homo sapiens
(Human)
Length = 587
Score = 222 bits (543), Expect = 1e-56
Identities = 123/348 (35%), Positives = 195/348 (56%), Gaps = 16/348 (4%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG 82
Y+P+ E Q ++ ++ K+ S+ L DF+ +V+G G++ V LV+ T
Sbjct: 210 YNPSSHESLDQVGEE-KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTD 268
Query: 83 KYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAG 141
+ YAMK+++KE + + I+ EK + N PF+V + F+ L++V+ ++ G
Sbjct: 269 RIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNG 328
Query: 142 GEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDF 201
G++ H+++ K E A+FY A++ LAL YLH ++YRDLK +N+L+D G+IK+TD+
Sbjct: 329 GDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDY 388
Query: 202 GFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF---- 254
G CK L G T T CGTP Y+APEI+ + YG SVDWW+LGVL+FEM AG PF
Sbjct: 389 GMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVG 448
Query: 255 FASDPMR-----IYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGT-LKDGVLDFK 308
+ +P + +++ I+ + R P SV+ ++ L D R G + G D +
Sbjct: 449 SSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQ 508
Query: 309 NHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSP 355
H +FR +DWD + ++ PPF P I NFD F E ++ +P
Sbjct: 509 GHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTP 556
>UniRef50_Q22A18 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 355
Score = 222 bits (542), Expect = 1e-56
Identities = 114/286 (39%), Positives = 168/286 (58%), Gaps = 11/286 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+ DF + VLG G+F V LVK GK+YA+K+L+K K+ + + I++ E+ IL G+N
Sbjct: 20 IEDFFMKAVLGKGSFAKVILVKKKDNGKFYAIKVLKKSKLEKQRHIDNVIAERNILVGVN 79
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY--- 172
PFV+ + Y F+++ LY+VL F GGE+F+ L K KF E + +E+
Sbjct: 80 HPFVIQLHYSFQNSEKLYFVLEFCPGGELFNLLHKAQKFTEDYLDCACNRTSSLIEHHIQ 139
Query: 173 --LHAC-ELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEII 226
+ C + V LKPEN++ID GYI+ITDFG K +T+++CGTPEYLAPEI+
Sbjct: 140 RSIEMCGQRVTTYLKPENVMIDFDGYIRITDFGLSKNNISNHEKTYSVCGTPEYLAPEIL 199
Query: 227 LSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIG 286
+G+ S DWWSLG L++E+ G PPF+ + +YE I P + S KD+I
Sbjct: 200 TMQGHEKSADWWSLGALIYELLTGLPPFYNQNREVMYELIKNQNVNIPDYISPICKDLIY 259
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
+LQ + R G K+G + KNH W +++DW+ +L PPF P
Sbjct: 260 RLLQKNPENRLG--KNGAFEIKNHPWLQDVDWEILLRKEYRPPFIP 303
>UniRef50_A0DPW4 Cluster: Chromosome undetermined scaffold_6, whole
genome shotgun sequence; n=6; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_6,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 391
Score = 221 bits (541), Expect = 2e-56
Identities = 117/288 (40%), Positives = 171/288 (59%), Gaps = 7/288 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
KS+ DF + LG GAFGIVF V+ T K YAMK +EKEKI + K ++ E+
Sbjct: 53 KSKGQINREDFVKIDKLGYGAFGIVFKVRQKTTNKIYAMKQIEKEKIFKNKLQNNTVLER 112
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGK-FEETSAKFYGAQVI 167
+L PF+V +KY F+ N ++Y+V+ IAGGE + L ++ E KF GA+V+
Sbjct: 113 NVLKQSKHPFIVRLKYAFQTNSHIYFVMENIAGGEFYKILSQVKTGLPENVVKFVGAEVV 172
Query: 168 LALEYLHA-CELVYRDLKPENILIDRTGYIKITDFGFCKLIR---GRTWTLCGTPEYLAP 223
LALEYL+ +++YRDLKPEN+L+ TG++K+TDFG + R +++T+ GT EYLAP
Sbjct: 173 LALEYLNTKLKVIYRDLKPENLLLTTTGHVKLTDFGLATMRRENGEKSYTVAGTAEYLAP 232
Query: 224 EIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS--DPMRIYEKIVAGKYRCPSHFSVEL 281
EI+ G+ VD W+LG+L++EM G PF S D I +KI+ + P S +
Sbjct: 233 EIVNKSGHSYEVDIWTLGILIYEMINGFTPFRDSNNDFKVISQKIIENQPIYPEKMSPQS 292
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
D+I +LQ + + R G DG + K H +F I WD + N ++ P
Sbjct: 293 VDLIKQILQTNPSERLGVKGDGYAELKRHSFFNGIIWDQMSNLKVTSP 340
>UniRef50_P87253 Cluster: Protein kinase C-like; n=6;
Pezizomycotina|Rep: Protein kinase C-like - Neurospora
crassa
Length = 1142
Score = 221 bits (540), Expect = 2e-56
Identities = 113/295 (38%), Positives = 172/295 (58%), Gaps = 7/295 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+ F VLG G FG V L + + K YA+K+L+KE I+ ++E EK++ N
Sbjct: 814 LDHFNFLAVLGKGNFGKVMLAETKKSRKLYAIKVLKKEFIIENDEVESIRSEKRVFLIAN 873
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+ + F+ +Y+V+ +I+GG++ H+++ G F A+FY A+V LAL+Y
Sbjct: 874 RERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQR-GMFGTKRAQFYAAEVCLALKY 932
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSK 229
H ++YRDLK +NIL+ G+IKI D+G CK T T CGTPE++APEI+L K
Sbjct: 933 FHENGVIYRDLKLDNILLTLDGHIKIADYGLCKEDMWYGSTTSTFCGTPEFMAPEILLDK 992
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
YG +VDWW+ GVL+++M PF D IY+ I+A + P H + I+ +L
Sbjct: 993 KYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLL 1052
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G+ + + +FR I+WD I + R+ PPF P+I+S DT+NFD
Sbjct: 1053 TREPDQRLGSGPTDAQEIMSQPFFRNINWDDIYHKRVQPPFLPQIKSATDTSNFD 1107
>UniRef50_Q0UME1 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1043
Score = 221 bits (539), Expect = 3e-56
Identities = 115/295 (38%), Positives = 171/295 (57%), Gaps = 7/295 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+ F VLG G FG V L + T + YA+K+L+KE I+ ++E EK++L N
Sbjct: 715 LDHFNFLAVLGKGNFGKVMLAETKSTKQLYAIKVLKKEFIIENDEVESVRSEKRVLLIAN 774
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ +Y+V+ +I+GG++ H+++ G F A+FY A+V LAL+Y
Sbjct: 775 KERHPFLVNLHACFQTETRVYFVMEYISGGDLMLHIQR-GTFGTKRAQFYAAEVCLALKY 833
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSK 229
H ++YRDLK +NIL+ G+IKI D+G CK T T CGTPE++APEI+L K
Sbjct: 834 FHENGVIYRDLKLDNILLTLDGHIKIADYGLCKEEMWYGSTTSTFCGTPEFMAPEILLDK 893
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
YG +VDWW+ GVL+++M PF D IY+ I+A + P H + I+ +L
Sbjct: 894 KYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLL 953
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ R G+ + +H +FR I+WD I + R+ PF P I S DT+NFD
Sbjct: 954 TREPEMRLGSGPTDAQEIMSHAFFRNINWDDIYHKRVPAPFIPTITSATDTSNFD 1008
>UniRef50_Q4RZQ9 Cluster: Chromosome 18 SCAF14786, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF14786, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 645
Score = 220 bits (538), Expect = 4e-56
Identities = 108/278 (38%), Positives = 170/278 (61%), Gaps = 5/278 (1%)
Query: 73 VFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP-FVVYMKYYFKDNVY 131
V LV+ TG+ YA+K+L+K+ +++ +E + EK++L + P F+ + F+
Sbjct: 329 VMLVEMKATGELYAVKILKKDVVIQDDDVECTMVEKRVLALQDKPPFLTQLHSCFQTVDR 388
Query: 132 LYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILID 191
LY+V+ ++ GG++ H++++GKF+E A FY A++ + L +LH ++YRDLK +N+++D
Sbjct: 389 LYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEIAVGLFFLHERGIIYRDLKLDNVMLD 448
Query: 192 RTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMS 248
G+IKI DFG CK ++ G T T CGTP+Y+APEII + YG+SVDWW+ GVLL+EM
Sbjct: 449 SEGHIKIADFGMCKENMVDGVCTRTFCGTPDYIAPEIIAYQPYGLSVDWWAYGVLLYEML 508
Query: 249 AGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFK 308
AG PPF D +++ I+ P S E I ++ ++R G ++G D +
Sbjct: 509 AGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMAKLPSKRLGCGQEGERDIR 568
Query: 309 NHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+H +FR IDW + N I PPF PK+ NFD F
Sbjct: 569 DHVFFRRIDWKRLENREIQPPFKPKVCGKA-AENFDKF 605
>UniRef50_A2D9C1 Cluster: AGC family protein kinase; n=4;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 474
Score = 220 bits (538), Expect = 4e-56
Identities = 116/318 (36%), Positives = 180/318 (56%), Gaps = 11/318 (3%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
K++DF KV+G G +G V L +HI T + A+K + K ++++ ++ E+ IL
Sbjct: 105 KMSDFRVLKVIGRGFYGKVTLCEHIATKEIVAIKSIHKSRLIQQNKVTTVISERNILAKA 164
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF+V +K+ F+ Y L ++ GGE+F H+++ G K Y A+++LAL +LH
Sbjct: 165 QHPFIVNLKFAFQSPSKFYLGLEYVPGGELFFHMQRYGNIRLDDCKIYIAEILLALNHLH 224
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILSKGYG 232
+ ++YRDLKPENIL+D G+IK+TDFG K + T T CGT EYLAPE++ + Y
Sbjct: 225 SLGVIYRDLKPENILLDANGHIKLTDFGLSKNLAHEVHTSTFCGTTEYLAPEVVNHQPYT 284
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
SVDWW+LGVL +E+ G PF + +++ I+ + + P +F+ E D I +L D
Sbjct: 285 YSVDWWALGVLTYELLFGTTPFAHQNRAKMFRNILDNEPQFPPNFNQEAIDFIKAMLTKD 344
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R T + K K+F+ ++WD +L +I P F P + + NFD F E+
Sbjct: 345 PLKR-PTFE----QIKQMKFFQNLNWDDVLQKKIQPKFVPASDNSNEANNFDPEFTSEQA 399
Query: 352 KDS---PVCLYEEEFADF 366
DS PV E+ A F
Sbjct: 400 ADSYVMPVFGSAEKLAGF 417
>UniRef50_Q9V3I5 Cluster: Chromosomal serine/threonine-protein
kinase JIL-1; n=2; Coelomata|Rep: Chromosomal
serine/threonine-protein kinase JIL-1 - Drosophila
melanogaster (Fruit fly)
Length = 1207
Score = 220 bits (538), Expect = 4e-56
Identities = 124/323 (38%), Positives = 181/323 (56%), Gaps = 15/323 (4%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSY 105
S+ LNDF+ +VLGTGA+G VFLV+ + GK YAMK+L K +V + K EH+
Sbjct: 252 SDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTK 311
Query: 106 YEKKILCGLNF-PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGA 164
E+ +L + PF+V + Y F+ + LY VL F GGE+F+HL FEE+ + Y A
Sbjct: 312 TERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIA 371
Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEY 220
+V+LALE LH ++YRD+K ENIL+D G+I ++DFG K++ R + CGT EY
Sbjct: 372 EVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEY 431
Query: 221 LAPEIILS--KGYGMSVDWWSLGVLLFEMSAGHPPFFASD----PMRIYEKIVAGKYRCP 274
+APEII + G+ +VDWWS+GVL FE+ G PF SD I +I + P
Sbjct: 432 MAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIP 491
Query: 275 SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI 334
S FS +D + +L+ + RR G + K H +F I+W + R P+ P +
Sbjct: 492 SSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTL 551
Query: 335 RSPGDTTNFDVFDEEKIKDSPVC 357
+ D NF +++ + P C
Sbjct: 552 TAEDDVQNFSNEFTDQVPEDPEC 574
Score = 67.3 bits (157), Expect = 6e-10
Identities = 50/174 (28%), Positives = 87/174 (50%), Gaps = 19/174 (10%)
Query: 94 KIVRLKQIEHSYYEKKILCGL---NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRK 150
KI+ L + S + I C L N +V F++ + V+ +++G E+ + +R
Sbjct: 652 KIIPLSKFRPSEVDALISCALDTTNHKNIVSYHGTFREKCETWIVMEYLSGPELTASIR- 710
Query: 151 MGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILI----DRTGYIKITDFG-FCK 205
+E S + Q+++A+ ++H+ ++ DLKPENI+ DRT +K+ DFG C
Sbjct: 711 ---MDEDSCREIFLQLVMAVRHIHSKHFIHGDLKPENIMFENREDRT--VKLIDFGSACY 765
Query: 206 LIRGRTW--TLCGTPEYLAPEIILSKG---YGMSVDWWSLGVLLFEMSAGHPPF 254
R ++W T +Y PE++ Y +VD + LG L+ M GH P+
Sbjct: 766 NNRFKSWKDKPRYTLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPY 819
>UniRef50_Q4RM42 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 766
Score = 220 bits (537), Expect = 5e-56
Identities = 118/324 (36%), Positives = 191/324 (58%), Gaps = 13/324 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++DF +VLG G+FG V L K +A+K+L+K+ I++ +E + EK++L
Sbjct: 436 ISDFTFLQVLGKGSFGKVMLAKLNSKDLVFAVKVLKKDIILQDDDVECTMTEKRVLSLAQ 495
Query: 116 -FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
P++ + F+ + L++V+ F+ GG++ H++K KFEE A+FY A++ AL +LH
Sbjct: 496 CHPYLTQLYCCFQTSDRLFFVMEFVNGGDLMFHIQKSRKFEEPRARFYTAEITSALMFLH 555
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGY 231
+ ++YRDLK +N+L+D+ G+ K+ DFG CK + G T T CGTP+Y+APEI+ Y
Sbjct: 556 SKGILYRDLKLDNVLLDKDGHCKLADFGMCKEGIFEGAATATFCGTPDYIAPEILQEMLY 615
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G SVDWW+LGVLL+EM +GH PF A + ++E I+ + S S E +++ +L
Sbjct: 616 GPSVDWWALGVLLYEMLSGHAPFEAENEDDLFESILNEEVLYASWLSTEAVNMLKALLTK 675
Query: 292 DTTRRYGTLKD--GVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDE 348
+ R G + G NH +F IDW+ + + PPF P+I++ D NFD F +
Sbjct: 676 NPAHRLGCVASDGGETAIVNHPFFTGIDWEKLNRRELEPPFKPRIKTAEDVNNFDPDFTQ 735
Query: 349 EKIKDSPV------CLYEEEFADF 366
E+ +P+ + +EEF +F
Sbjct: 736 EEPTLTPIDDPLIPSINQEEFLNF 759
>UniRef50_A0E3G7 Cluster: Chromosome undetermined scaffold_76, whole
genome shotgun sequence; n=5; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_76,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 864
Score = 219 bits (536), Expect = 7e-56
Identities = 111/294 (37%), Positives = 165/294 (56%), Gaps = 9/294 (3%)
Query: 46 WDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSY 105
+ K SN KL++ K LG G FG V+LV+ K YA+K + K +IV H
Sbjct: 482 YQKKDYSNLKLDNLICIKKLGQGQFGNVYLVRTAQDEKLYALKCISKAQIVEQHLERHLA 541
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
EK++L +NFPF++ KD Y+Y+++ FI G E+F +R++G + ++FY
Sbjct: 542 QEKQVLSTINFPFLMQFYKSMKDQNYIYFLVEFIKGMELFDAIREIGLLTTSDSQFYIGS 601
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLA 222
+++ +EYLH +++YRD+KPENI++D GY+++ D G K + RT+T+ GTP Y+A
Sbjct: 602 LLICVEYLHKLQIIYRDIKPENIMVDEKGYLRMIDMGTAKFLNQKSIRTYTIIGTPHYMA 661
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFF--ASDPMRIYEKIVAGKYRCPSHF-SV 279
PEII KGY SVD WS+GV L+E G P+ A DP IYE+I P+
Sbjct: 662 PEIITGKGYTFSVDLWSIGVCLYEFMCGGVPYAEDADDPYEIYEEIQKKSITFPTFMKDK 721
Query: 280 ELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
+ K I +L R G G K + WF + DWD +++ + PPF PK
Sbjct: 722 KAKKFIEQLLSKTPEARLG---GGYASLKANTWFDKFDWDKLMDKELKPPFLPK 772
>UniRef50_P36583 Cluster: Protein kinase C-like 2; n=1;
Schizosaccharomyces pombe|Rep: Protein kinase C-like 2 -
Schizosaccharomyces pombe (Fission yeast)
Length = 1016
Score = 219 bits (536), Expect = 7e-56
Identities = 113/307 (36%), Positives = 175/307 (57%), Gaps = 10/307 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF VLG G FG V L + + YA+K+L+KE I+ ++E + EK++ N
Sbjct: 680 LEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVAN 739
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ +Y+V+ F++GG++ H+++ +F A+FY A+V LAL+Y
Sbjct: 740 RERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE-QFSRRRAQFYAAEVCLALKY 798
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSK 229
H ++YRDLK +NIL+ G++K+ D+G CK T T CGTPE++APEI+L +
Sbjct: 799 FHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAPEILLEQ 858
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y SVDWW+ GVL+++M G PF D I++ I++ + P H + I+ +L
Sbjct: 859 QYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYPIHMPRDSVSILQQLL 918
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
D +R G+ + D H +F I+WD I + R PP+ P + SP DT FDEE
Sbjct: 919 TRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSLNSPTDT---KYFDEE 975
Query: 350 KIKDSPV 356
++ PV
Sbjct: 976 FTRELPV 982
>UniRef50_A0CC53 Cluster: Chromosome undetermined scaffold_166,
whole genome shotgun sequence; n=7; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_166,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 736
Score = 219 bits (535), Expect = 9e-56
Identities = 109/286 (38%), Positives = 174/286 (60%), Gaps = 6/286 (2%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
+ L DF K +G G F V++VK G++YAMK+++KE I++ K+ E+ I+
Sbjct: 250 AKVSLKDFIFVKCIGVGGFSRVYMVKKKSNGRFYAMKLIDKEFILQHKKQGIVQNERDIM 309
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
L+ PF++ ++Y F+ ++ +VL F +GGE+F LR++ + E A+FY ++ LA+
Sbjct: 310 TVLDHPFIIKLEYAFESKNFIIFVLEFCSGGELFWQLRQVKRMTEYQARFYFTEICLAMF 369
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ +VYRD+KPENILID G+I+I DFG K ++ CG+PEY+APE++L
Sbjct: 370 YLHSLSIVYRDIKPENILIDIDGHIRIADFGLSKPNMTEEDYAYSFCGSPEYMAPEMLLK 429
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPS--HFSVELKDIIG 286
G+ + VD + LG LL+E+ G PP+++ D IYE I+ + P + S E+KD++
Sbjct: 430 IGHNVQVDHYCLGALLYELVTGLPPYYSRDTEEIYESILNEELTFPEKLNLSNEIKDLLK 489
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
+L + R K G+L+ H WF++ D SIL ++ PPF P
Sbjct: 490 GLLSKQPSERLCANK-GLLELFTHPWFKDCDLVSILLKKVQPPFKP 534
>UniRef50_Q5CWD4 Cluster: Cyclic nucleotide (CGMP)-dependent protein
kinase with 3 cNMP binding domains and a Ser/Thr kinase
domain; n=3; Cryptosporidium|Rep: Cyclic nucleotide
(CGMP)-dependent protein kinase with 3 cNMP binding
domains and a Ser/Thr kinase domain - Cryptosporidium
parvum Iowa II
Length = 965
Score = 219 bits (534), Expect = 1e-55
Identities = 110/288 (38%), Positives = 171/288 (59%), Gaps = 3/288 (1%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E+ +++D + + +G G FG+V++V++I +G YA+K + K +I+ L H E+ I
Sbjct: 614 ETRVQMSDLKILQTIGKGTFGVVYMVENIKSGNKYALKKISKSRILALNMQAHVKLERSI 673
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
L + PF++ + FKD+ +Y + I GGE++ L+++G A+FY +ILAL
Sbjct: 674 LALNDHPFIIKLVRTFKDSENIYLLTELIPGGELYDALQRIGLLTRYQAQFYIGSIILAL 733
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKG 230
EYLH +VYRDLKPENIL+D GYIK+ DFG K I GR++TL GTP Y+APE+IL KG
Sbjct: 734 EYLHERSIVYRDLKPENILLDSQGYIKLIDFGCAKKIAGRSYTLAGTPHYMAPEVILGKG 793
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPF--FASDPMRIYEKIVAGKYRCPSHFS-VELKDIIGH 287
Y +S D W++G+ L+E G PF A D + I++ I+ K P H + V+ +II
Sbjct: 794 YNLSCDAWAIGICLYEFLCGCLPFGNDAVDHLEIFKDILTSKLVFPRHLNDVDTVNIIKR 853
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIR 335
+L R G G + K++ +F++ ++D +L P K R
Sbjct: 854 LLCRVPEVRMGCSATGYKEIKDNVFFKDFNFDRLLGRSYVAPLVRKYR 901
>UniRef50_A0C512 Cluster: Chromosome undetermined scaffold_15, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_15,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 342
Score = 219 bits (534), Expect = 1e-55
Identities = 112/321 (34%), Positives = 191/321 (59%), Gaps = 10/321 (3%)
Query: 29 EQYSQYLKKLRQDFVE---SWDDKSES-NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKY 84
E + KKL + +E S +K E + +L +F + VLG G FG V L +HI T +Y
Sbjct: 10 EDNQEEAKKLNPNQIEEQASQKEKEEEISYQLQNFTFKNVLGAGLFGKVLLAEHIKTKQY 69
Query: 85 YAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEM 144
+A+K+++K+++ +E E +IL PF++ + + F++ L+ F+ GG++
Sbjct: 70 FAIKIIDKKQLEDQNFVES---EHQILQQTQSPFIIKLYFTFENKNKLFLGTEFVNGGDL 126
Query: 145 FSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFC 204
F HL+ +F E +FY ++ILAL+YLH ++YRDLKPENIL+D+ G+IK+TDFG
Sbjct: 127 FVHLKNNVQFSEERTRFYAVELILALKYLHENRIIYRDLKPENILLDQFGHIKLTDFGLS 186
Query: 205 KLIRGR-TWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIY 263
K + T+T CGTPEY+APEI+L +G+ VDW+SLG+L+++M G PF++ +
Sbjct: 187 KYKFSQITYTACGTPEYVAPEILLERGHNECVDWYSLGILIYQMLCGSIPFYSKQLDEMI 246
Query: 264 EKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILN 323
+K ++ + P + + + D+I + + + ++R G G + H +F EID +++
Sbjct: 247 DKRLSQPFEFPKYLNQKAVDLIKGLTENEVSKRLGF--KGADEILRHPFFEEIDIEAMSK 304
Query: 324 SRIHPPFFPKIRSPGDTTNFD 344
++ PPF P+++ D D
Sbjct: 305 RQVEPPFRPQLQGKKDLRYLD 325
>UniRef50_A0BNJ0 Cluster: Chromosome undetermined scaffold_118,
whole genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_118,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 662
Score = 218 bits (533), Expect = 2e-55
Identities = 104/287 (36%), Positives = 180/287 (62%), Gaps = 6/287 (2%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E L DF K +G G F +V+LV+ TGK+YA+K+++KE I+ K+ + E+ I
Sbjct: 247 EPKVGLKDFIFLKNIGVGGFSLVYLVRKKDTGKFYALKLIDKEFIIAKKKQQIVLNERNI 306
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ LN PF++++ Y F+ ++ +VL F GGE+F L+++ + E A FY +++ L L
Sbjct: 307 MTLLNSPFLLHLSYAFESRQFVVFVLEFCQGGELFFQLKQIKRMSEEQACFYISEICLGL 366
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTPEYLAPEIIL 227
+ +H+ ++YRD+KPENIL+D G+++I DFG K GR ++ CG+PEY+APE++L
Sbjct: 367 QEIHSLNILYRDIKPENILMDIEGHVRIADFGLSKPEIGREEKAYSFCGSPEYMAPEMLL 426
Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSV--ELKDII 285
G+ +VD++ LG LL+E+ G PP+++++ +IY+ I+ K P+ ++ E+K ++
Sbjct: 427 KLGHSQTVDFYCLGALLYELLTGLPPYYSTNTNQIYQDILYSKLSFPNDLTLSREVKSLL 486
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
+L+ D +R G K GV + H +F +ID+ + ++ PPF P
Sbjct: 487 IALLEKDPIQRLGA-KGGVQEILKHPFFSQIDFKQLALKKVKPPFKP 532
>UniRef50_O75582 Cluster: Ribosomal protein S6 kinase alpha-5; n=62;
Eumetazoa|Rep: Ribosomal protein S6 kinase alpha-5 -
Homo sapiens (Human)
Length = 802
Score = 218 bits (533), Expect = 2e-55
Identities = 122/319 (38%), Positives = 183/319 (57%), Gaps = 16/319 (5%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYYEKKIL 111
+ +FE KVLGTGA+G VFLV+ I TGK YAMK+L+K IV + K EH+ E+++L
Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105
Query: 112 CGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ PF+V + Y F+ L+ +L +I GGE+F+HL + +F E + Y +++LAL
Sbjct: 106 EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 165
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYLAPEII 226
E+LH ++YRD+K ENIL+D G++ +TDFG K R ++ CGT EY+AP+I+
Sbjct: 166 EHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIV 225
Query: 227 L--SKGYGMSVDWWSLGVLLFEMSAGHPPFFA----SDPMRIYEKIVAGKYRCPSHFSVE 280
G+ +VDWWSLGVL++E+ G PF + I +I+ + P S
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSAL 285
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
KD+I +L D +R G + K H +F++I+WD + ++ PF P IR D
Sbjct: 286 AKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDV 345
Query: 341 TNF-DVFDEEKIKDSPVCL 358
+NF + F E SP L
Sbjct: 346 SNFAEEFTEMDPTYSPAAL 364
Score = 117 bits (282), Expect = 4e-25
Identities = 81/253 (32%), Positives = 125/253 (49%), Gaps = 22/253 (8%)
Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV 120
+ K LG G+F I H + + +A+K++ K R++ LC P +V
Sbjct: 428 KDKPLGEGSFSICRKCVHKKSNQAFAVKIISK----RMEANTQKEITALKLCE-GHPNIV 482
Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVY 180
+ F D ++ + V+ + GGE+F ++K F ET A + +++ A+ ++H +V+
Sbjct: 483 KLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVH 542
Query: 181 RDLKPENILIDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGYGMS 234
RDLKPEN+L IKI DFGF +L L C T Y APE++ GY S
Sbjct: 543 RDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDES 602
Query: 235 VDWWSLGVLLFEMSAGHPPFFASD-------PMRIYEKIVAGKY----RCPSHFSVELKD 283
D WSLGV+L+ M +G PF + D + I +KI G + + S E KD
Sbjct: 603 CDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKD 662
Query: 284 IIGHVLQVDTTRR 296
+I +L VD +R
Sbjct: 663 LIQGLLTVDPNKR 675
>UniRef50_Q02156 Cluster: Protein kinase C epsilon type; n=34;
Coelomata|Rep: Protein kinase C epsilon type - Homo
sapiens (Human)
Length = 737
Score = 217 bits (531), Expect = 3e-55
Identities = 114/313 (36%), Positives = 185/313 (59%), Gaps = 9/313 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GL 114
L++F KVLG G+FG V L + + YA+K+L+K+ I++ ++ + EK+IL
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
P++ + F+ L++V+ ++ GG++ +++ KF+E ++FY A+V AL +LH
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +NIL+D G+ K+ DFG CK ++ G T T CGTP+Y+APEI+ Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G SVDWW+LGVL++EM AG PPF A + ++E I+ P S E I+ +
Sbjct: 585 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 644
Query: 292 DTTRRYGTL--KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ +R G + ++G K H +F+EIDW + +I PPF P+I++ D N FD++
Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNN---FDQD 701
Query: 350 KIKDSPVCLYEEE 362
++ PV +E
Sbjct: 702 FTREEPVLTLVDE 714
>UniRef50_Q4SG88 Cluster: Chromosome 17 SCAF14597, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 17
SCAF14597, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 754
Score = 217 bits (529), Expect = 5e-55
Identities = 116/308 (37%), Positives = 181/308 (58%), Gaps = 7/308 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GL 114
L +F KVLG G+FG V L + + + YA+K+L+K+ I++ ++ + EK+IL
Sbjct: 425 LQNFVFIKVLGKGSFGKVMLAELKGSDEVYAVKVLKKDVILQDDDVDCTLTEKRILALAR 484
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
P++ + F+ L++V+ ++ GG++ +++ KF+E ++FY A+V AL +LH
Sbjct: 485 KHPYLTQLFCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEARSRFYAAEVTSALMFLH 544
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +NIL+D G+ K+ DFG CK ++ G T T CGTP+Y+APEI+ Y
Sbjct: 545 RHGVIYRDLKLDNILLDADGHCKLADFGMCKEGILNGITTTTFCGTPDYIAPEILQELDY 604
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G SVDWW+LGVL++EM AG PPF A + ++E I+ P S E I+ +
Sbjct: 605 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 664
Query: 292 DTTRRYGTLKDGVLD--FKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDE 348
+R G + L+ K H +FREIDW + +I PPF P+I++ D NFD F
Sbjct: 665 SPNKRLGCVVAQGLEEAIKLHPFFREIDWTLLEQRKIRPPFKPRIKTKRDVNNFDQDFTR 724
Query: 349 EKIKDSPV 356
E+ +PV
Sbjct: 725 EEPVLTPV 732
>UniRef50_Q23PX4 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila SB210
Length = 1706
Score = 217 bits (529), Expect = 5e-55
Identities = 102/284 (35%), Positives = 171/284 (60%), Gaps = 6/284 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L F + +G G F V+LV+ TGK +A+K+++K+ I+ K+ E+ I+ +
Sbjct: 961 LESFHLIRCIGLGGFSRVYLVQKKDTGKMFALKLIDKKFIIENKKEVIVQNERNIMASIA 1020
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ ++Y F+ YL + + + AGGE+F HLR++ + E A+FY ++ L ++YLH
Sbjct: 1021 HPFLLKLEYSFESKSYLGFCMEYCAGGELFYHLRRIKRMSEEMARFYFVEICLGIDYLHK 1080
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEIILSKGYG 232
++YRD+KPENIL+D G+++I DFG K I ++ CG+PEY+APE+++ G+
Sbjct: 1081 RHIIYRDIKPENILLDLDGHVRIGDFGLSKPDMDINEHAYSFCGSPEYMAPEMLMKVGHT 1140
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH--FSVELKDIIGHVLQ 290
+VD++ LG LL+E+ G PPF++ D IY++I++ P H S+ELK+++ +L
Sbjct: 1141 YTVDFYCLGALLYELVTGLPPFYSHDTDAIYQRILSEDLDFPDHVELSIELKNLLKGLLA 1200
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI 334
R G +K+G+ D H WF+ I +L I PP P +
Sbjct: 1201 KHPQNRLG-IKNGIRDILAHSWFKPIKIGDVLEKLIEPPLKPNV 1243
>UniRef50_UPI00006CDDB0 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 880
Score = 216 bits (528), Expect = 7e-55
Identities = 103/284 (36%), Positives = 176/284 (61%), Gaps = 6/284 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL- 114
L F+ K +G G F V+L + G++ A+K+++K+ +++ ++ + Y EK + L
Sbjct: 158 LKHFDVLKKIGLGGFSEVYLARRKDNGQFVALKVIKKKTLIKKRRKLYVYNEKNTMIALK 217
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L +VL + GGE+F HL + +F+E A AQ++ +E+LH
Sbjct: 218 DNPFIVQFFFAFQTREKLIFVLEYCPGGELFYHLNQERRFKEEQAGILFAQILEGIEFLH 277
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTPEYLAPEIILSKGY 231
+ ++YRDLKPENIL+D GY+K+ DFG K+++ + +T CG+ EY+APE+I KG+
Sbjct: 278 SKNIIYRDLKPENILLDMNGYVKLADFGLSKVLKSKDQLNYTFCGSHEYMAPEMIQKKGH 337
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRC-PSHFSVELKDIIGHVLQ 290
+VD++SLGVLL+E+ AG PPF + + + EK + + + P FS +L+D I ++
Sbjct: 338 TFAVDYYSLGVLLYELVAGIPPFSSDNKTDLLEKALTKEVKFPPKQFSSQLQDFIKQLMI 397
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI 334
D T+R G K G+ + + H W ++I++D I + + PP P+I
Sbjct: 398 KDPTKRLGA-KSGISEIRKHPWCKKINFDKIRSLKFDPPIIPRI 440
>UniRef50_O61225 Cluster: Serine/Threonine protein kinase; n=1;
Sycon raphanus|Rep: Serine/Threonine protein kinase -
Sycon raphanus
Length = 724
Score = 216 bits (528), Expect = 7e-55
Identities = 108/300 (36%), Positives = 176/300 (58%), Gaps = 5/300 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S L+DF KVLG G+FG V L + + +Y A+K+L+K+ ++ +E + EK+
Sbjct: 388 SSKRYTLSDFHLLKVLGKGSFGKVMLAQVKKSKQYLAIKVLKKDVVLEDDDVECTMIEKR 447
Query: 110 ILCGLNF-PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V++ F+ +LY+V+ ++ GG++ H+++ G+F E +FY +++I
Sbjct: 448 VLSSTSIHPFLVHLHSAFQTEGHLYFVMEYVNGGDLMFHIQQQGRFSEDRTRFYVSEIIC 507
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK-LIRGR--TWTLCGTPEYLAPEI 225
L++LH+ ++YRDLK +N+++ G+IKI DFG CK I G T T CGTP+Y+APEI
Sbjct: 508 GLQHLHSRGIIYRDLKLDNVMLSSRGHIKIADFGMCKENICGENTTSTFCGTPDYIAPEI 567
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
I + Y SVDWW+LGVL +EM G PF D +++ I+ + P + E I
Sbjct: 568 IQGEQYNHSVDWWALGVLTYEMLLGQSPFSGDDEESLFQSIMNDQVVYPVWLTREAAAFI 627
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+L + +R G+ + + +F+ IDW + + I PF P ++S GD NFDV
Sbjct: 628 SKLLVREPDKRLGS-DPKQSNPRGEAFFKTIDWAKLERAEIAAPFVPNVKSAGDACNFDV 686
>UniRef50_P34722 Cluster: Protein kinase C-like 1; n=3;
Caenorhabditis|Rep: Protein kinase C-like 1 -
Caenorhabditis elegans
Length = 704
Score = 216 bits (528), Expect = 7e-55
Identities = 115/339 (33%), Positives = 186/339 (54%), Gaps = 9/339 (2%)
Query: 27 KQEQYSQYLKKLRQDFVES-WD--DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGK 83
K QYS +K +++++ W D L F KVLG G+FG V LV+ +
Sbjct: 340 KSHQYSVEEQKETDEYMDNIWGGGDGPVKKFALPHFNLLKVLGKGSFGKVMLVELKGKNE 399
Query: 84 YYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
+YAMK L+K+ I+ E +Y E+++L PF+ + F+ N YL++V+ ++ GG
Sbjct: 400 FYAMKCLKKDVILEDDDTECTYIERRVLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGG 459
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
++ H++++ KF+E +FY ++++AL++LH ++YRDLK +N+L+D G+IK+ DFG
Sbjct: 460 DLMHHIQQIKKFDEARTRFYACEIVVALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFG 519
Query: 203 FCKL----IRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASD 258
K G T CGTP+Y++PEII + Y +VD+WS GVL++EM G PF
Sbjct: 520 MAKTEMNRENGMASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEG 579
Query: 259 PMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDW 318
+++ I+ + P S E + + + R G + + H +FR +DW
Sbjct: 580 EDELFDSILNERPYFPKTISKEAAKCLSALFDRNPNTRLGMPECPDGPIRQHCFFRGVDW 639
Query: 319 DSILNSRIHPPFFPKIRSPGDTTNF-DVFDEEKIKDSPV 356
N ++ PPF P I+S D +NF D F EK +PV
Sbjct: 640 KRFENRQVPPPFKPNIKSNSDASNFDDDFTNEKAALTPV 678
>UniRef50_A0D8K8 Cluster: Chromosome undetermined scaffold_41, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_41,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 698
Score = 216 bits (527), Expect = 9e-55
Identities = 107/276 (38%), Positives = 163/276 (59%), Gaps = 6/276 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHI--VTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116
F+ + LG G FG V+LV+ I KYYAMK+L+KE I I+ + EK +L +N
Sbjct: 391 FQFYQKLGEGGFGQVYLVEKIGQEPKKYYAMKILQKEDIDTSNIIKSAQIEKDVLKIMNH 450
Query: 117 PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHAC 176
PF+V + Y F+ +LY V+ GG++ +HL + +F E K Y A++ LALE LH
Sbjct: 451 PFIVKLNYAFQTLDHLYLVMDLCPGGDLATHLELVNQFPEHIVKIYAAEITLALEALHQQ 510
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEIILSKGYGM 233
+++RDLKPEN+++D+ G+ ++TDFG K + CGT YLAPE+++ KG+G
Sbjct: 511 GIIFRDLKPENVVLDKDGHAQLTDFGLSKQGIDEEMLNQSFCGTLAYLAPEMLMKKGHGR 570
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
VDW+ LG+ ++E+ G PP++ ++ + E I + P H S E KDII +L D
Sbjct: 571 QVDWYMLGIFIYELLVGAPPYYDAEKEILKENIKRAPLKIPRHLSQEAKDIIIQLLIRDP 630
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
RR G K+ + K+H WF +I+W N ++ PP
Sbjct: 631 KRRLG-CKEDAKEIKSHPWFNDINWQDCYNKKLQPP 665
>UniRef50_Q69G16 Cluster: Protein kinase C type beta; n=2;
Bilateria|Rep: Protein kinase C type beta - Schistosoma
mansoni (Blood fluke)
Length = 618
Score = 215 bits (526), Expect = 1e-54
Identities = 113/276 (40%), Positives = 160/276 (57%), Gaps = 4/276 (1%)
Query: 73 VFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVY 131
V L + T + YA+K+L+K+ +++ ++ + E+++L PF+V + F+
Sbjct: 303 VMLAERKDTDELYAVKILKKDVVLQDDDVDCAMIERRVLALQRKPPFLVQLHSTFQTMDR 362
Query: 132 LYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILID 191
LY+V+ F+ GG++ ++K GKF+E A FY A+V + L +LH DLK +N+L+D
Sbjct: 363 LYFVMEFVNGGDLMFRIQKEGKFKEPIAVFYAAEVAVGLFFLHDSRNYLSDLKLDNLLLD 422
Query: 192 RTGYIKITDFGFCKL-IRG--RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMS 248
G+IKI DFG CK I G T T CGTP+Y+APEI+L K YG SVDWWS GVLL+EM
Sbjct: 423 ADGHIKIADFGMCKDGITGDVTTHTFCGTPDYIAPEILLYKPYGKSVDWWSYGVLLYEML 482
Query: 249 AGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFK 308
AG PPF D ++ I+ P S E I +L D +R G DG + K
Sbjct: 483 AGQPPFEGEDEEDLFANILQHTISYPKSLSKESVSICKALLTRDPMKRLGCGSDGEKEIK 542
Query: 309 NHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
H +FR IDWD I + PP+ P SP DT+NFD
Sbjct: 543 EHLFFRRIDWDKIALRLVQPPYKPVTLSPRDTSNFD 578
>UniRef50_O62569 Cluster: Serine/Threonine protein kinase; n=1;
Suberites domuncula|Rep: Serine/Threonine protein kinase
- Suberites domuncula (Sponge)
Length = 763
Score = 215 bits (526), Expect = 1e-54
Identities = 108/294 (36%), Positives = 174/294 (59%), Gaps = 5/294 (1%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
KL +F+ K+LG G+FG V L + I + KYYA+K L+K+ ++ +E + EK+IL G
Sbjct: 432 KLEEFQFLKLLGKGSFGKVLLAQQIGSNKYYAIKALKKDVVLEDDDVEATMVEKRILALG 491
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PFV ++ F+ + +L++V+ ++ GG++ H++ KF+ A+FY A+++ L++L
Sbjct: 492 SECPFVTHLHSTFQSSSHLFFVMEYLNGGDLMFHIQLHHKFKLPRARFYAAEILAGLQFL 551
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK-LIRGRT--WTLCGTPEYLAPEIILSKG 230
H+ ++YRDLK +NIL+D G+ KI DFG C+ I G + T CGTP+Y++PEII K
Sbjct: 552 HSKGIIYRDLKLDNILLDSEGHCKIADFGMCRENIFGSSTAGTFCGTPDYISPEIIKGKR 611
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVD+WS GVL +EM G PPF D +++ I + + D + +LQ
Sbjct: 612 YTFSVDFWSYGVLCYEMITGQPPFGGEDEDELFDSICNSQIPFSRYLDAYTIDFLDKLLQ 671
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G + D + H +FR ID+ + I P+ P ++S D +NFD
Sbjct: 672 REPIQRLGYMGDR-QPIRKHPFFRSIDFARLEKREIAAPYKPVVKSAQDASNFD 724
>UniRef50_P05129 Cluster: Protein kinase C gamma type; n=98;
Eumetazoa|Rep: Protein kinase C gamma type - Homo
sapiens (Human)
Length = 697
Score = 215 bits (526), Expect = 1e-54
Identities = 117/306 (38%), Positives = 174/306 (56%), Gaps = 10/306 (3%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S ++DF VLG G+FG V L + + + YA+K+L+K+ IV+ ++ + EK+
Sbjct: 342 SPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKR 401
Query: 110 ILC-GLNFP-----FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYG 163
+L G P F+ + F+ LY+V+ ++ GG++ H++++GKF+E A FY
Sbjct: 402 VLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYA 461
Query: 164 AQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEY 220
A++ + L +LH ++YRDLK +N+++D G+IKITDFG CK + G T T CGTP+Y
Sbjct: 462 AEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDY 521
Query: 221 LAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVE 280
+APEII + YG SVDWWS GVLL+EM AG PPF D +++ I+ P S E
Sbjct: 522 IAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSRE 581
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
I L +R G+ DG + H +FR IDW+ + I PPF P+
Sbjct: 582 AVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPR-PCGRSG 640
Query: 341 TNFDVF 346
NFD F
Sbjct: 641 ENFDKF 646
>UniRef50_Q91948 Cluster: PKN; n=3; Euteleostomi|Rep: PKN - Xenopus
sp. (clawed frog)
Length = 901
Score = 215 bits (525), Expect = 2e-54
Identities = 106/299 (35%), Positives = 176/299 (58%), Gaps = 7/299 (2%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
S L++F VLG G FG V L ++ TG+ +A+K L+K I+ ++E EK++
Sbjct: 567 SQLSLDNFRLLAVLGRGHFGKVLLSEYKETGELFAVKALKKGDIIARDEVESLLCEKRVF 626
Query: 112 CGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++ PF++ + F+ + +V+ ++AGG+ +H+ F ++ A FY A V+L
Sbjct: 627 VAVSDASHPFLLSLLGCFQTADSVCFVMDYMAGGDSMTHIHSE-VFSQSRAMFYAACVLL 685
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEI 225
L++LH+ +VYRDLK +N+L+D GY+K+ D+G CK G RT T CGTPE+LAPE+
Sbjct: 686 GLQFLHSRNIVYRDLKLDNLLLDSEGYVKLADYGLCKEGMGPSDRTSTFCGTPEFLAPEV 745
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ Y +VDWW GVL++EM G PF + +++ IV + R P + E I+
Sbjct: 746 LTDASYTRAVDWWGFGVLIYEMMVGESPFPGDEEEEVFDSIVNDEVRYPRFLTAEAIAIM 805
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+L+ + RR G + D K +F+++D++++L+ R+ PPF P ++ P D +NFD
Sbjct: 806 RRLLRRNPERRLGAGERDAEDVKKQPFFKDMDFEALLSRRLPPPFTPCVKGPHDISNFD 864
>UniRef50_A2F0I9 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 405
Score = 215 bits (525), Expect = 2e-54
Identities = 115/311 (36%), Positives = 177/311 (56%), Gaps = 11/311 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++DF V+G G +G V LV++ T + AMK + K ++++ K++ E+ IL +N
Sbjct: 85 MDDFNIISVIGRGFYGKVMLVENKYTKEICAMKTIHKARLIKEKKVHTVIAERNILVKVN 144
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V +KY F++ LY + ++ GGE+F ++ + + + Y A+V LALEY+H+
Sbjct: 145 HPFIVNIKYAFQNETKLYIGMEYVPGGELFHMMQIVENLPMKAIRIYVAEVGLALEYIHS 204
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKG 230
+VYRDLKPENILI G+IK+TDFG K++ T T CGT EYL PE+I +
Sbjct: 205 LGIVYRDLKPENILITAEGHIKLTDFGLAKVLPEDEGEDTTKTFCGTNEYLPPEMIKREY 264
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
YG +DWW+LG+L +E+ G PF ++YEKI + P + + D I +L+
Sbjct: 265 YGAMIDWWALGILTYELIYGDTPFVHKSKHKMYEKICNEEPHFPDNEDPNVVDFITKLLK 324
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
D +R LK D KNH +F + ++ +L ++ PPF P+I S NFD F +E
Sbjct: 325 KDPKKR-AKLK----DLKNHPFFNGLKFEDVLALKVKPPFRPRIGSDRSVKNFDSEFTKE 379
Query: 350 KIKDSPVCLYE 360
DS + E
Sbjct: 380 ACIDSTAAIVE 390
>UniRef50_A0E8C9 Cluster: Chromosome undetermined scaffold_82, whole
genome shotgun sequence; n=14; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_82,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 910
Score = 215 bits (525), Expect = 2e-54
Identities = 104/300 (34%), Positives = 177/300 (59%), Gaps = 7/300 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF K +G G F V++V+ GK+YA+K+++K+ I+ ++ E+ I+ +
Sbjct: 400 LKDFTLVKCIGVGGFSRVYMVRKRDNGKFYALKLIDKKFILDNQKEIIVQNERDIMVQME 459
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
FV + Y F+ Y+ +VL + AGGE+F HLRK+ + E AKFY ++ + + YLH+
Sbjct: 460 NQFVTPLHYAFETKYYIAFVLDYCAGGELFYHLRKLKRLNEQDAKFYFVEICIGMAYLHS 519
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKGYG 232
+VYRD+KPENIL+D G++ ++DFG K ++ CG+PEY+APE+++ G+
Sbjct: 520 KNIVYRDIKPENILLDLQGHLLLSDFGLSKPDMTADDFAYSFCGSPEYMAPEMLMKTGHN 579
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVE--LKDIIGHVLQ 290
VD + LG LL+E+ G PPF++ + IY I+ P + + LK++I +LQ
Sbjct: 580 YLVDCYCLGALLYELVTGLPPFYSHNTQEIYNSILTETVEFPQYVQISPVLKELILQLLQ 639
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK-IRSPGDTTNFDVFDEE 349
D T R G G+++ H+WF ++D+++I+N ++ P+ P+ ++ D F+ D E
Sbjct: 640 KDPTERLG-YNGGIVEILTHQWFHDVDFEAIVNKQLKTPYKPEPLKYNFDEEEFNKGDAE 698
>UniRef50_Q6CBU3 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome C of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 478
Score = 215 bits (525), Expect = 2e-54
Identities = 122/312 (39%), Positives = 175/312 (56%), Gaps = 9/312 (2%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +DFE KVLG GAFG V LV+ TG YA K L+K ++ K+ + E+
Sbjct: 129 SRGKLTTSDFEPIKVLGCGAFGKVLLVREKSTGHLYAQKQLKKASMIVEKKALQTKTERA 188
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL + P++V + Y +D LY +L + GGE+F HL E +A FY A++ILA
Sbjct: 189 ILESVRHPYIVKLFYALQDQEKLYLILEYAQGGELFHHLATEHMLPEQTASFYVAEMILA 248
Query: 170 LEYLHA-CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRT-WTLCGTPEYLAPEIIL 227
L +LH +VYRDLKPEN ++D+ G++ +TDFG K+ T T GTPEY+APE++
Sbjct: 249 LSHLHLNVGVVYRDLKPENCMLDQDGHLVLTDFGLSKVATNDTCTTFSGTPEYMAPEVLQ 308
Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK-YRCPSHFSVELKDIIG 286
K Y SVDWWSLG + F++ G+PPF +D +I KI K R P + S + KD +
Sbjct: 309 GKEYDYSVDWWSLGAVTFDLLTGNPPFTGNDYQKILAKIDKCKAMRYPFYLSQDAKDFLN 368
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSR---IHPPFFPKIRSPGDTTNF 343
L+ RR G+ +D + K ++FR++DWD +L +R + PP P I P NF
Sbjct: 369 GCLKKCPNRRLGS-RD-LEKVKKMRFFRKLDWD-LLEARDPSLEPPIKPLITDPILAENF 425
Query: 344 DVFDEEKIKDSP 355
+ + P
Sbjct: 426 STTFTDMVLSPP 437
>UniRef50_Q8C050 Cluster: Ribosomal protein S6 kinase alpha-5; n=16;
Coelomata|Rep: Ribosomal protein S6 kinase alpha-5 - Mus
musculus (Mouse)
Length = 863
Score = 215 bits (525), Expect = 2e-54
Identities = 120/319 (37%), Positives = 180/319 (56%), Gaps = 16/319 (5%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYYEKKIL 111
+ +FE KVLGTGA+G VFLV+ I GK YAMK+L+K IV + K EH+ E+++L
Sbjct: 45 IENFELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 104
Query: 112 CGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ PF+V + Y F+ L+ +L +I GGE+F+HL + +F E + Y +++LAL
Sbjct: 105 EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 164
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYLAPEII 226
E+LH ++YRD+K ENIL+D G++ +TDFG K R ++ CGT EY+AP+I+
Sbjct: 165 EHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIV 224
Query: 227 L--SKGYGMSVDWWSLGVLLFEMSAGHPPFFA----SDPMRIYEKIVAGKYRCPSHFSVE 280
G+ +VDWWSLGVL++E+ G PF + I +I+ + P S
Sbjct: 225 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSTV 284
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
KD++ +L D +R G + K H +F +I WD + ++ PF P IR D
Sbjct: 285 AKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKIKWDDLAAKKVPAPFKPVIRDELDV 344
Query: 341 TNF-DVFDEEKIKDSPVCL 358
+NF + F E SP L
Sbjct: 345 SNFAEEFTEMDPTYSPAAL 363
Score = 100 bits (240), Expect = 5e-20
Identities = 62/184 (33%), Positives = 96/184 (52%), Gaps = 17/184 (9%)
Query: 130 VYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENIL 189
++ + V+ + GGE+F +++ F ET A + +++ A+ ++H +V+RDLKPEN+L
Sbjct: 556 LHTFLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLL 615
Query: 190 IDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGYGMSVDWWSLGVL 243
IK+ DFGF +L L C T Y APE++ GY S D WSLGV+
Sbjct: 616 FTDENDNLEIKVIDFGFARLKPPDNQPLKTPCFTLHYAAPELLTHNGYDESCDLWSLGVI 675
Query: 244 LFEMSAGHPPFFASD-------PMRIYEKIVAGKY----RCPSHFSVELKDIIGHVLQVD 292
L+ M +G PF + D + I +KI G + + S E KD+I +L VD
Sbjct: 676 LYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVD 735
Query: 293 TTRR 296
+R
Sbjct: 736 PNKR 739
>UniRef50_A2FMG9 Cluster: AGC family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 417
Score = 215 bits (524), Expect = 2e-54
Identities = 120/325 (36%), Positives = 186/325 (57%), Gaps = 19/325 (5%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E+ K+N++E VLG G +G V L KH TGK+ A+K + K+ ++ +K+++ E+ I
Sbjct: 95 ENTEKINEYEIISVLGRGFYGKVVLAKHKKTGKFCAIKSIHKKVLLDMKKVDTIMVERDI 154
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL-RKMGKFEETSAKFYGAQVILA 169
L PF+V + F+ Y VL +++GG++F HL + K Y A++ +A
Sbjct: 155 LKSTKSPFIVSLLSSFQTPSKFYLVLEYVSGGDLFMHLTNNNNEISVDQIKLYIAELAVA 214
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEII 226
LE LH ++YRDLKPEN+LI G+IK+TDFG K++ + T TLCGT EYLAPE+I
Sbjct: 215 LEQLHKDHIIYRDLKPENVLICEDGHIKLTDFGISKMLNEKQSTTNTLCGTGEYLAPEVI 274
Query: 227 LSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVE---LKD 283
KGY ++DWW LG+L++EM G PF ++ +Y I+ + P+ F +E ++
Sbjct: 275 SDKGYTEAIDWWQLGILMYEMVVGKTPFADTNKSIMYSNIM---NKNPNFFPIEDENARN 331
Query: 284 IIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT-TN 342
+I H+L+ D +R G + KN K+F DW + + + FPK S ++ N
Sbjct: 332 LIAHLLRKDPAKR-----AGFEEIKNSKFFEGFDWTDMKSRDAY--MFPKDSSSSESLNN 384
Query: 343 FD-VFDEEKIKDSPVCLYEEEFADF 366
F+ F EE+ +DS E+F DF
Sbjct: 385 FNKKFTEEEAEDSDAMPVMEKFGDF 409
>UniRef50_Q8TFJ3 Cluster: Protein kinase A catalytic subunit; n=1;
Mucor racemosus|Rep: Protein kinase A catalytic subunit
- Rhizomucor racemosus (Mucor circinelloides f.
lusitanicus)
Length = 605
Score = 214 bits (523), Expect = 3e-54
Identities = 102/295 (34%), Positives = 177/295 (60%), Gaps = 9/295 (3%)
Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107
D ++N K DF +++G G+ G V+ V +G+ YAMK+L K ++ +++ ++ E
Sbjct: 236 DPKKANLKPEDFRIVRMIGQGSVGKVYEVIKRDSGRTYAMKVLSKRLLLAENEVDTAFNE 295
Query: 108 KKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166
+ +L L+ PF+ +KY F+ +L+ V+ + GGE+F L + E +F+ A++
Sbjct: 296 RNVLVQSLSSPFIANLKYSFQTTNHLFLVMDYFPGGELFDFLERERCLSEKRCQFFAAEI 355
Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTP-----EYL 221
+ A + +HA +VYR+LKPE+IL+D G+I +TDFG CK ++ + + G P EYL
Sbjct: 356 VCAFDNIHARNIVYRNLKPESILLDAHGHIALTDFGLCKQLKNKMDLIQGVPQVITQEYL 415
Query: 222 APEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH--FSV 279
APE+++ K YGM+ DWWSLGVL+FE+ G PPF + + ++ +I+ + P+ +
Sbjct: 416 APEMVMQKPYGMAADWWSLGVLMFELLTGSPPFHSVEQGELFRQILEAPIKFPAGGCITE 475
Query: 280 ELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI 334
E KD I +L+ D +R G+ D V K H +F++++WD + ++ PF P++
Sbjct: 476 EAKDFICQLLERDPAKRLGSHGD-VAQVKAHPFFKDLNWDVVYKKQMQLPFVPEV 529
>UniRef50_Q234E6 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 829
Score = 214 bits (522), Expect = 4e-54
Identities = 117/327 (35%), Positives = 185/327 (56%), Gaps = 17/327 (5%)
Query: 17 LIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSE-SNAKLNDFERQKVLGTGAFGIVFL 75
L+ G SP ++ +K+ Q +E + KS+ +N KL+D K LG G FG VFL
Sbjct: 458 LVNLFGESPFDVINKNKQVKE--QSAIEESNLKSQVNNMKLSDLIVIKKLGFGQFGSVFL 515
Query: 76 VKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYV 135
VK K Y +K + K ++V +H EK+++ NFPFV+ FKD+ +Y++
Sbjct: 516 VKEKGKKKLYGLKCVSKAQVVEQSLEKHIQNEKQVMEFNNFPFVMKFLRSFKDDRCIYFL 575
Query: 136 LPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGY 195
L FI G E+F +R++G ++FY +IL LEYLH+ ++YRD+KPENI++D GY
Sbjct: 576 LEFIQGMELFDVIREIGLLSTYDSQFYIGSLILTLEYLHSNYIIYRDIKPENIMVDHAGY 635
Query: 196 IKITDFGFCKLIRG------RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSA 249
+K+ D G K+++ RT+T+ GTP Y+APE+I KGY VD WS+G+ L+E
Sbjct: 636 LKLIDMGTAKIMKSKAGTVTRTFTIIGTPHYMAPEVISGKGYNFLVDLWSVGICLYEFMC 695
Query: 250 GHPPFF--ASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDG--VL 305
G+ PF A DP IYE+I+ + + P++ +KD + L + + ++ G
Sbjct: 696 GYVPFAEEAEDPYEIYEEIIKKEIQFPAY----MKDAVAKQLMLQLLNKIPEIRLGGSYN 751
Query: 306 DFKNHKWFREIDWDSILNSRIHPPFFP 332
K++ WF+ DW +L ++ P+ P
Sbjct: 752 ALKSNAWFKNFDWHQLLERKLKAPWIP 778
>UniRef50_A0CUG4 Cluster: Chromosome undetermined scaffold_28, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_28,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 532
Score = 214 bits (522), Expect = 4e-54
Identities = 104/284 (36%), Positives = 173/284 (60%), Gaps = 9/284 (3%)
Query: 47 DDKSESNAKLNDFERQ----KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIE 102
D++ + K D+ +Q K L G G V LV+ I T KYY K+++K+ ++ +
Sbjct: 196 DNQKQPIRKSYDYSQQYRLLKYLYQGMLGQVILVQSIKTDKYYVFKLMQKQDVITTDHLN 255
Query: 103 HSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFY 162
H+ E+K+L + PF++ + F+ + L YVLPF GG++++HL+K + +E KF
Sbjct: 256 HALIERKLLEIFDHPFIIKLVQAFETDDQLIYVLPFYQGGDLYTHLKKETRLKEERVKFL 315
Query: 163 GAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR--TWTLCGTPEY 220
AQ+I+AL Y+H + VYRDLKPENIL+D +GYI +TD G CK + +++ G+ EY
Sbjct: 316 VAQLIMALGYMHDKDYVYRDLKPENILMDSSGYIALTDLGLCKQLPNNQLSYSFTGSVEY 375
Query: 221 LAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH--FS 278
+APE+I + GY +DWW LG+L +E+ G PF+ + +++E I + R ++ S
Sbjct: 376 IAPEMITAVGYNRMIDWWMLGILAYELIFGITPFYCDNQSQVFESIQEREVRFSTNIAIS 435
Query: 279 VELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSIL 322
+E KD I ++L+ D R G +D +D + H+WF++I++ I+
Sbjct: 436 LECKDFITNLLRKDPKERLGFKRD-FIDLQLHQWFKDINFGEII 478
>UniRef50_Q6BHW6 Cluster: Debaryomyces hansenii chromosome G of
strain CBS767 of Debaryomyces hansenii; n=3;
Saccharomycetaceae|Rep: Debaryomyces hansenii chromosome
G of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 449
Score = 214 bits (522), Expect = 4e-54
Identities = 123/332 (37%), Positives = 192/332 (57%), Gaps = 20/332 (6%)
Query: 32 SQYLKKLRQDFVESWDDKSESN---AKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
S Y +++ +V S ++ + KL+DFE KVLG GA+G V LV+ I T + +A K
Sbjct: 70 SSYEIDIQESYVSSLNNTNNFKNYKPKLSDFEPIKVLGRGAYGKVILVREISTNRLFAQK 129
Query: 89 MLEKEKIV-----RLKQIEHS--YYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAG 141
L+K +V + QI +S EK IL +N P +V + Y F+DN +Y +L +++G
Sbjct: 130 QLKKASLVINETNEIHQINYSRTINEKSILEIVNHPNIVSLYYAFQDNDKVYLILEYLSG 189
Query: 142 GEMFSHLRKMGKFEETSAKFYGAQVILALEYLH-ACELVYRDLKPENILIDRTGYIKITD 200
GE+F HL + E +A +Y AQ+ILAL YLH ++YRDLKPEN +++ G + +TD
Sbjct: 190 GELFHHLAQEKFMSEKNASYYIAQIILALRYLHNKLGVIYRDLKPENCMLNSYGNLVLTD 249
Query: 201 FGFCKL--IRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASD 258
FG K+ + ++ GT +Y+APEI+ S+ Y SVDWWSLG + +++ G PPF ++
Sbjct: 250 FGLSKVSTTDEKKHSMTGTVQYMAPEILKSEPYTYSVDWWSLGCVAYDLLTGSPPFNGNN 309
Query: 259 PMRIYEKIVAGK--YRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREI 316
+I EK+++ K + P + S++ KD++ +LQ + +R+ D L K H++FR I
Sbjct: 310 NKKIIEKVISSKKTLKFPFYLSLDAKDLLRKLLQPNPYKRFNIDNDFDL-LKKHRFFRHI 368
Query: 317 DWDSILNSRIH----PPFFPKIRSPGDTTNFD 344
DW + + PP P I P NFD
Sbjct: 369 DWSQLESPDYQLETLPPILPIITDPILAENFD 400
>UniRef50_Q6P5Z2 Cluster: Serine/threonine-protein kinase N3; n=20;
Mammalia|Rep: Serine/threonine-protein kinase N3 - Homo
sapiens (Human)
Length = 889
Score = 214 bits (522), Expect = 4e-54
Identities = 113/296 (38%), Positives = 169/296 (57%), Gaps = 7/296 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L DF VLG G FG V LV+ TGKYYA+K L+K++++ +IE Y EK+IL +
Sbjct: 555 RLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAV 614
Query: 115 N---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
PF++ + F+ + + +V F+ GG++ + + F E A+FY A V+L L+
Sbjct: 615 GCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE-DVFPEPQARFYVACVVLGLQ 673
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILS 228
+LH +++YRDLK +N+L+D G++KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 674 FLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQ 733
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LGVLL+EM G PF +++ IV P SV+ + I +
Sbjct: 734 EAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKL 793
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
LQ +R G + + K +FR +W ++L I PPF P + P D F+
Sbjct: 794 LQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFE 849
>UniRef50_Q8MUA6 Cluster: Protein kinase C-related kinase; n=1;
Hydra vulgaris|Rep: Protein kinase C-related kinase -
Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 1030
Score = 213 bits (521), Expect = 5e-54
Identities = 107/299 (35%), Positives = 168/299 (56%), Gaps = 7/299 (2%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
S + +F VLG G FG V L ++ T + +A+K L+K I+ +++ EK+I
Sbjct: 696 SGLSMENFRCISVLGRGHFGKVLLAEYKTTKELFAIKALKKGDIISRDEVDSLMSEKRIF 755
Query: 112 CGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
N PF+V + F+ ++ +V+ + GG++ H+ + F E FY VIL
Sbjct: 756 ETANSVRHPFLVNLFSCFQTKDHVCFVMEYAPGGDLMMHIHEE-VFSEPRTIFYSGCVIL 814
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEI 225
L+YLH ++VYRDLK +N+L+D GY+KI DFG CK G +T T CGTPE+LAPE+
Sbjct: 815 GLQYLHEHDIVYRDLKLDNLLLDAEGYVKIADFGLCKEGMGFGQKTGTFCGTPEFLAPEV 874
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ Y +VDWW LGVL+FEM G PF D +++ IV + R P S + ++
Sbjct: 875 LTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSNDSIALM 934
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+L+ + RR G+ D K +++++ WDS++ ++ PF P ++ P D +NFD
Sbjct: 935 RRLLRKNPERRLGSSIKDAEDIKKQPFYKDMKWDSLIQRKLKTPFIPTVKHPEDVSNFD 993
>UniRef50_Q4Q7M5 Cluster: Rac serine-threonine kinase, putative;
n=3; Leishmania|Rep: Rac serine-threonine kinase,
putative - Leishmania major
Length = 510
Score = 213 bits (521), Expect = 5e-54
Identities = 117/309 (37%), Positives = 179/309 (57%), Gaps = 14/309 (4%)
Query: 41 DFVESWDDKSESNAK--LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRL 98
D + ++ S + K L DFE++ VLG G++G VF+V T K+YAMK + EK+ R
Sbjct: 86 DTLRHYNSSSSGSEKVTLRDFEKKFVLGKGSYGKVFMVVKKDTDKWYAMKEMSAEKM-RQ 144
Query: 99 KQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETS 158
+I+ + E+ IL ++ PF+V++ Y F++ LY +L +AGGE+F+++ + +E
Sbjct: 145 AEIKAPFAERIILEEIDHPFIVHLHYSFQEQGNLYMILDLLAGGELFTYIEQHAPLDEEV 204
Query: 159 AKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTWTLCG 216
KFY A+V LAL YLH+ ++YRDLKPEN++ DR G+ +TDFG K + T CG
Sbjct: 205 VKFYAAEVALALGYLHSRNIIYRDLKPENVVFDRDGHACLTDFGLAKANVHEPNAVTYCG 264
Query: 217 TPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH 276
T EYLAPE++ +G +VDWWSLG+++ EM PF+ +PM++ KI+ P H
Sbjct: 265 TNEYLAPELLKGVPHGKAVDWWSLGLMMCEMLFNDLPFYDENPMQMQMKILTEDVAFPPH 324
Query: 277 FSV--ELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI 334
+ E KD+I +L + RR TL+ FK HK F +D+ + ++ P P
Sbjct: 325 IQITEETKDLIRCLLNKNPERRLQTLE----AFKAHKCFSNLDFCLLEARKLKAPITP-- 378
Query: 335 RSPGDTTNF 343
P NF
Sbjct: 379 -DPNPAHNF 386
>UniRef50_UPI0000499138 Cluster: hypothetical protein 53.t00028;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 53.t00028 - Entamoeba histolytica HM-1:IMSS
Length = 964
Score = 213 bits (520), Expect = 6e-54
Identities = 116/305 (38%), Positives = 176/305 (57%), Gaps = 9/305 (2%)
Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107
D++ +N L DFE K + GA+ V+LV+ VT YAMK+++K ++R ++ E
Sbjct: 561 DETWNNIGLKDFEIIKRINGGAYSSVYLVRKKVTNDIYAMKIMKKADMIRKNVVDGVLAE 620
Query: 108 KKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
K IL P VV M Y F+D L+ V+ + GG++ L +G +ET+AK Y A+++
Sbjct: 621 KTILQRAQTPSVVKMYYAFQDTHNLFLVMEYCPGGDLRCLLSNVGYLDETTAKIYSAEIV 680
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWT-----LCGTPEYLA 222
LALEY+H+ ++RDLKP+N+LID+ G++ +TDFG + T L TP+Y+A
Sbjct: 681 LALEYIHSLGCIHRDLKPDNVLIDKNGHLLLTDFGLSTVGSKIEQTVEDSRLVCTPDYVA 740
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHF--SVE 280
PE I+S Y D++SLG ++FE G PPF P I++ I GKY PS S E
Sbjct: 741 PESIVSFQYSRCSDYFSLGSMIFEFICGIPPFHEETPDAIFQNIRTGKYSWPSSINPSNE 800
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
LK I+ +L V+ +R G V + K+H WF I+W+++LN F P++ + DT
Sbjct: 801 LKSIVSGLLTVEVKKRLG--YKSVQEIKSHPWFEGINWNTLLNESREDIFVPELDNETDT 858
Query: 341 TNFDV 345
F+V
Sbjct: 859 GYFEV 863
>UniRef50_UPI000069F1C6 Cluster: UPI000069F1C6 related cluster;
n=11; Xenopus tropicalis|Rep: UPI000069F1C6 UniRef100
entry - Xenopus tropicalis
Length = 348
Score = 213 bits (520), Expect = 6e-54
Identities = 115/312 (36%), Positives = 174/312 (55%), Gaps = 6/312 (1%)
Query: 37 KLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIV 96
K++ + E + K +A+ DF R KVLG G+FG V LV+++ Y A+K+L+KE I
Sbjct: 32 KIKPSYAEKYSKKMCFSAR--DFRRIKVLGRGSFGKVLLVEYLPANIYCALKVLKKEDIN 89
Query: 97 RLKQIEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFE 155
L++++ EK+I +N F+V + F +L++V+ F+AGG + +HL G F+
Sbjct: 90 TLEELQRILAEKEIGKTVNPDNFIVDLYATFSTKFHLFFVMEFVAGGSLRTHLDTCGHFD 149
Query: 156 ETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTW 212
AKFY A ++L LE +H ++V+RDLKP N+L+D+ GYIKI DFG K G RT
Sbjct: 150 LERAKFYAACILLGLEAVHMKDVVHRDLKPGNLLMDKDGYIKIADFGIGKTGIGYGDRTG 209
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR 272
T+ G+ Y+APE++ + Y +VDWW+LGV+ +EM G PF D I + IV +
Sbjct: 210 TMIGSLAYMAPEVLRKEMYTRAVDWWALGVITYEMLLGKKPFTGYDGDCICDSIVGVEPL 269
Query: 273 CPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
P + I +L + R G+ + D H +F I WD IL + PF P
Sbjct: 270 FPESLDPDAVSFISELLNKNPEERLGSTEGDAADVAEHPFFNNIVWDDILERKATAPFIP 329
Query: 333 KIRSPGDTTNFD 344
+ P D T F+
Sbjct: 330 SLNGPEDVTYFE 341
>UniRef50_A7TMA2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 1164
Score = 213 bits (520), Expect = 6e-54
Identities = 112/295 (37%), Positives = 167/295 (56%), Gaps = 7/295 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC--- 112
L+DF KVLG G FG V L K TG+ A+K+L+K+ I++ IE + EKK+
Sbjct: 834 LDDFILMKVLGKGNFGKVLLSKSKNTGRICAIKVLKKDHIIQNHDIESARAEKKVFLLAT 893
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+ + F+ +Y+ + FI GG++ H++ + AKFY A+V+LAL+Y
Sbjct: 894 KAKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLSVRRAKFYSAEVLLALKY 952
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSK 229
H ++YRDLK ENIL+ G+IKI D+G CK RT T CGTPE++APEI+ +
Sbjct: 953 FHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDDMWYGNRTSTFCGTPEFMAPEILKEQ 1012
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW+ GVLL++M PF D ++ I+ + P + ++ I +L
Sbjct: 1013 EYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGDIVQIFQGLL 1072
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
D +R G L+ +FR I++D +LN R+ PP+ PKI SP DT+ F+
Sbjct: 1073 TKDPEKRLGAGPRDALEVMGEPFFRNINFDDVLNLRVQPPYIPKISSPEDTSYFE 1127
>UniRef50_A5DZ73 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 1157
Score = 213 bits (520), Expect = 6e-54
Identities = 124/361 (34%), Positives = 192/361 (53%), Gaps = 20/361 (5%)
Query: 3 DSEIKRHINSPRGDLIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQ 62
D + H+ SP D Q P+K S K+ R+ L+DF+
Sbjct: 786 DVDTSNHVESPFADQHQQLQKEPSKAHSKSSKSKRRRR------------KVGLDDFQFL 833
Query: 63 KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN---FPFV 119
VLG G FG V L + T K A+K+L+K+ IV + E EK++ N PF+
Sbjct: 834 AVLGKGNFGKVMLAESRHTQKLCAIKVLKKDFIVENDEAESVKSEKRVFLTANKEMHPFL 893
Query: 120 VYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELV 179
+ + F+ +Y+V+ +I+GG++ H++ +F AK+Y +V+L L+Y H +V
Sbjct: 894 LNLHCCFQTENRIYFVMEYISGGDLMWHIQN-NRFTARRAKYYACEVLLGLKYFHDSGIV 952
Query: 180 YRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYGMSVD 236
YRDLK +NIL+ G+IKI D+G CK + G T T CGTPE++APEI+ K Y SVD
Sbjct: 953 YRDLKLDNILLTTKGHIKIADYGLCKENMWHGNTTSTFCGTPEFMAPEIVTGKKYDRSVD 1012
Query: 237 WWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR 296
WW+ GVLLF+M PF D I+ I + + P S ++ +L D +R
Sbjct: 1013 WWAFGVLLFQMLLCQSPFKGDDEDDIFNAIEHDEVKFPVSLSGPTVLVLQALLTKDPQQR 1072
Query: 297 YGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSP 355
G+ + + H +F+++++D +LN R+ PPF P+++S D +NFD F E + +P
Sbjct: 1073 LGSSERDAEEIMEHPYFQDVNFDDVLNCRVPPPFIPELKSEHDYSNFDKEFTSETPRLTP 1132
Query: 356 V 356
V
Sbjct: 1133 V 1133
>UniRef50_A0BD03 Cluster: Chromosome undetermined scaffold_10, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_10,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 363
Score = 213 bits (519), Expect = 8e-54
Identities = 104/285 (36%), Positives = 181/285 (63%), Gaps = 15/285 (5%)
Query: 54 AKLNDFERQKVLGTGAFGIVFLVKHIVTGK--YYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
A+L+DF++ K+LG GA+G V LV++ GK +YAMK+LEK+ I + QI H E+KIL
Sbjct: 41 AQLSDFKKLKLLGKGAYGRVMLVEYDKNGKQKFYAMKILEKKNIRKESQIRHVLDERKIL 100
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
N FVV ++Y F+++ LY+++ ++ GG+++ H++ F + +FY A+++ L+
Sbjct: 101 EKSNSNFVVKLRYAFQNHARLYFIVDYMEGGDLYYHIKSQPTFPDKFIRFYAAEILFGLQ 160
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILS 228
+LH+ ++YRDLKPENIL+ ++G+IK++DFG K++ + T CGT +YLAPE++ +
Sbjct: 161 HLHSLNVIYRDLKPENILLSQSGHIKLSDFGLSKILDDFNDKADTCCGTIDYLAPEVLGN 220
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYE----KIVAGKYRCPSHFSVELKDI 284
+GY + D++SLG L++EM G PPF++ + + + ++V +CP + +D+
Sbjct: 221 EGYSFACDFYSLGCLIYEMYFGMPPFYSKNKRLMIQNRSIRLVPFSEQCPQ----DARDL 276
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
+ +L+VD +R G + G NH +F E+D + +I P
Sbjct: 277 LTRLLEVDPKKRLG--RKGAEQILNHAYFLELDLQKMKELQIQAP 319
>UniRef50_UPI00006CF9D0 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 1220
Score = 212 bits (518), Expect = 1e-53
Identities = 103/286 (36%), Positives = 170/286 (59%), Gaps = 9/286 (3%)
Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107
++ E ++DF K LG G VFLV+H + K +A+KM+ K + K++E E
Sbjct: 117 NQKEQELNIHDFTFLKCLGKGGTSDVFLVRHRESCKLFALKMIPKTHLSEYKRLEQLLRE 176
Query: 108 KKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166
+KIL PF+ + F+ +L ++L F GGE+F HL+ K E +KFY ++
Sbjct: 177 RKILIDAAKAPFIASLHACFESEYHLNFLLEFYCGGELFFHLQNR-KLTENESKFYFVEI 235
Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTPEYLAP 223
++ EYLH+ +++YRDLKPENI++D G++++TDFG K+ R T + CG+PEY+AP
Sbjct: 236 LICFEYLHSNKILYRDLKPENIVLDMDGHVRLTDFGLSKIGMHREEMTDSFCGSPEYMAP 295
Query: 224 EIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKD 283
E++L +GY SVD+++LG L+E+ G PPF+A++ I + I + P + + L++
Sbjct: 296 EVLLRQGYNYSVDFYTLGAFLYELVTGLPPFYANNTETILKNIANEELEVPDYLNPHLRE 355
Query: 284 IIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
++ +L R + + D K+ KWF +++W ILN +I PP
Sbjct: 356 LLYQLLDKRPNHRIKSFE----DIKSCKWFSDVNWKDILNLKIQPP 397
>UniRef50_A2ELF7 Cluster: AGC family protein kinase; n=4;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 469
Score = 212 bits (518), Expect = 1e-53
Identities = 112/304 (36%), Positives = 171/304 (56%), Gaps = 8/304 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++DF ++G G +G V L + TG YA+K + K +++ + E+ ++
Sbjct: 112 MDDFNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGRTCAVIAERNLMMKAK 171
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
FPF+V + + F+ Y+ L ++ GG++ H ++GK AK Y AQ+ LA+ YLH
Sbjct: 172 FPFLVSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPIFDAKLYAAQIGLAITYLHG 231
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIR--GRTWTLCGTPEYLAPEIILSKGYGM 233
+VYRDLKPEN+L+D GYIK+ DFG K I T T CGTPEY++PE+IL K YG
Sbjct: 232 IGIVYRDLKPENVLLDGQGYIKLVDFGLSKDINQVKTTRTFCGTPEYISPELILKKNYGY 291
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
+VD W+LGVL++E+ G PPF + ++Y+KIV + + P+ L DII +L D
Sbjct: 292 AVDEWALGVLMYEIIFGDPPFVDENENKLYDKIVLEEPKYPADADPNLVDIIKKLLVKDP 351
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF-DEEKIK 352
+R +D K+H +F +ID+ + N P + PK+ + NFD + E
Sbjct: 352 AKR-----PKFIDLKSHPFFADIDFKKVYNKEYKPSYVPKLTTRLSLENFDPYITNENPN 406
Query: 353 DSPV 356
DS V
Sbjct: 407 DSYV 410
>UniRef50_P36582 Cluster: Protein kinase C-like 1; n=2;
Schizosaccharomyces pombe|Rep: Protein kinase C-like 1 -
Schizosaccharomyces pombe (Fission yeast)
Length = 988
Score = 212 bits (518), Expect = 1e-53
Identities = 110/315 (34%), Positives = 176/315 (55%), Gaps = 7/315 (2%)
Query: 36 KKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI 95
K + ES + ++ L+DF VLG G FG V L ++ V K+YA+K+L+KE I
Sbjct: 641 KDANRSVPESPRREKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAI 700
Query: 96 VRLKQIEHSYYEKKILCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
++ +++E EK + N PF++ + F+ + +Y+V+ +I GG++ H+++
Sbjct: 701 LKNEELESLKTEKHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQ- 759
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRG 209
+F A+FYGA+V LAL+Y H + YRDLK +NIL+ G+I+I D+G CK L+
Sbjct: 760 QFSVKRARFYGAEVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGN 819
Query: 210 RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG 269
T T CGTPE++APEI+L + Y VDWW+ GVL+++M G PF D I++ I++
Sbjct: 820 TTSTFCGTPEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSD 879
Query: 270 KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
+ P + + ++ +L D +R G+ + H +F I WD + N P
Sbjct: 880 EPLFPINMPADAVSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPS 939
Query: 330 FFPKIRSPGDTTNFD 344
+ P I P D NFD
Sbjct: 940 YKPLINDPRDLNNFD 954
>UniRef50_UPI00015B57A5 Cluster: PREDICTED: similar to CG10261-PE;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG10261-PE - Nasonia vitripennis
Length = 716
Score = 212 bits (517), Expect = 1e-53
Identities = 114/336 (33%), Positives = 190/336 (56%), Gaps = 16/336 (4%)
Query: 36 KKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI 95
++L D + + S+ L+DFE +V+G G++ V +V+ T + YAMK+++K +
Sbjct: 180 EELALDEMAGAEGASDRQYSLSDFELIRVIGRGSYAKVLMVELKQTKRIYAMKVIKKALV 239
Query: 96 VRLKQIEHSYYEKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKF 154
+ I+ EK + N PF+V + F+ L++V+ F+ GG++ H+++ +
Sbjct: 240 TDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMFHMQRQRRL 299
Query: 155 EETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IR--GRT 211
E A+FY A++ LAL +LH ++YRDLK +N+L+D G++K+TD+G CK +R T
Sbjct: 300 PEEHARFYAAEISLALNFLHTKGIIYRDLKLDNVLLDHEGHVKLTDYGMCKEGVREGDTT 359
Query: 212 WTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF----FASDPMR-----I 262
T CGTP Y+APEI+ + YG SVDWW+LGVL++EM AG PF + +P + +
Sbjct: 360 ATFCGTPNYIAPEILRGEDYGFSVDWWALGVLVYEMLAGRSPFDIAGASENPDQNTEDYL 419
Query: 263 YEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLK--DGVLDFKNHKWFREIDWDS 320
++ I+ R P SV+ ++ L D R G + + LD H +F+ IDWD
Sbjct: 420 FQVILQKTIRIPRSLSVKATSVLKGFLCKDPAERLGCGRSPNAFLDIMTHPFFKAIDWDM 479
Query: 321 ILNSRIHPPFFPKIRSPGDTTNF-DVFDEEKIKDSP 355
+ ++ PP+ P++ S D NF F +E + +P
Sbjct: 480 LEQKQVTPPYKPQLDSDRDLANFPPEFTDEPVYLTP 515
>UniRef50_UPI00015B4E6B Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 972
Score = 212 bits (517), Expect = 1e-53
Identities = 121/331 (36%), Positives = 188/331 (56%), Gaps = 23/331 (6%)
Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQI-EH 103
D + F+ KVLGTGA+G VFLV+ + G+ YAMK+L+K IV+ K++ EH
Sbjct: 110 DSGGQRVDMTHFDLLKVLGTGAYGKVFLVRKRIGVDVGQLYAMKVLKKATIVQKKKMTEH 169
Query: 104 SYYEKKILCGL-NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFY 162
+ E+++L + + PF+V + Y F+ + L+ +L +++GGE+F+HL + KF E + Y
Sbjct: 170 TKTERQVLEAVRDSPFLVTLHYAFQTDAKLHLILDYVSGGELFTHLYQRDKFTEDEVRIY 229
Query: 163 GAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI-------RGRTWTLC 215
++ILALE LH ++YRD+K ENIL+DR G+I +TDFG K RT++ C
Sbjct: 230 VGEIILALEQLHKLGIIYRDIKLENILLDREGHIILTDFGLSKEFLPHERDSNPRTYSFC 289
Query: 216 GTPEYLAPEIIL--SKGYGMSVDWWSLGVLLFEMSAGHPPFFA----SDPMRIYEKIVAG 269
GT EY+APE++ S G+ ++VDWWS+GVL +E+ G PF + I +I+
Sbjct: 290 GTIEYMAPEVVRGGSAGHNVAVDWWSVGVLTYELLTGSSPFTVEGEKNTQSEISRRILKM 349
Query: 270 KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFR----EIDWDSILNSR 325
P+ S ++D I +L D R G + K H +FR +W ++
Sbjct: 350 DPPMPTFLSPTVRDFIARLLTKDPRVRLGGGPRDAKELKEHDFFRIAPPPFNWSALERRE 409
Query: 326 IHPPFFPKIRSPGDTTNF-DVFDEEKIKDSP 355
+ PPF P+I DT+NF + F + +DSP
Sbjct: 410 VPPPFVPRITHELDTSNFSEEFTKMVAEDSP 440
Score = 97.9 bits (233), Expect = 4e-19
Identities = 60/203 (29%), Positives = 103/203 (50%), Gaps = 13/203 (6%)
Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVY 121
++ LG G+F + +H TG+ +A+K+L + +++ + + P +V
Sbjct: 507 EEPLGDGSFSVCRRCRHRQTGQEFAVKILSR-------RVDCGHEASLLRSCQGHPNIVK 559
Query: 122 MKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYR 181
+ +D + Y V+ ++GGE+ + R F E A Q+ AL ++H+ +++R
Sbjct: 560 LIEVHQDRAHNYIVMELLSGGELLTRSRT-APFSEQQASAIMRQLGSALRFMHSRGVLHR 618
Query: 182 DLKPENILIDRTGY---IKITDFGFCKLIRG--RTWTLCGTPEYLAPEIILSKGYGMSVD 236
D+KPEN++ +G IK+ DFGF + R T C T Y APE++ + Y S D
Sbjct: 619 DIKPENLVFAHSGPDAPIKLVDFGFACMKRSCEPLHTPCFTLPYAAPEVLANLDYDESCD 678
Query: 237 WWSLGVLLFEMSAGHPPFFASDP 259
WSLG +L+ M + PPF P
Sbjct: 679 IWSLGAVLYSMLSDRPPFRTGSP 701
>UniRef50_UPI0000D5755E Cluster: PREDICTED: similar to ribosomal
protein S6 kinase, 90kDa, polypeptide 5 isoform a; n=2;
Endopterygota|Rep: PREDICTED: similar to ribosomal
protein S6 kinase, 90kDa, polypeptide 5 isoform a -
Tribolium castaneum
Length = 928
Score = 212 bits (517), Expect = 1e-53
Identities = 122/347 (35%), Positives = 194/347 (55%), Gaps = 21/347 (6%)
Query: 27 KQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKH---IVTGK 83
K E Y ++ + D V ++ F+ KVLGTGA+G VFLV+ +
Sbjct: 44 KDEDYDNPIRTPQHDKVNL---SGVDRVNMSHFDLLKVLGTGAYGKVFLVRKRGGADNNR 100
Query: 84 YYAMKMLEKEKIVRLKQI-EHSYYEKKILCGL-NFPFVVYMKYYFKDNVYLYYVLPFIAG 141
YAMK+L+K IV+ K+ EH+ E+++L + + PF+V + Y F+ + L+ +L ++AG
Sbjct: 101 LYAMKVLKKATIVQKKKTTEHTKTERQVLEAVRDNPFLVTLHYAFQTDAKLHLILDYVAG 160
Query: 142 GEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDF 201
GE+F+HL + F E + Y ++ILALE LH+ ++YRD+K ENIL+D +G+I +TDF
Sbjct: 161 GELFTHLYQREHFTEDEVRIYIGEIILALERLHSLGIIYRDIKLENILVDESGHIVLTDF 220
Query: 202 GFCKLI--RG----RTWTLCGTPEYLAPEIIL--SKGYGMSVDWWSLGVLLFEMSAGHPP 253
G K + G R ++ CGT EY+APE++ ++G+ ++VDWWS+GVL +E+ G P
Sbjct: 221 GLSKELPREGDNDQRAYSFCGTIEYMAPEVVKGGTQGHDIAVDWWSVGVLTYELLTGASP 280
Query: 254 FFA----SDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKN 309
F + I +I+ P ++ D I +L D +R G + + K
Sbjct: 281 FTVEGEKNTQQEISRRILKTTPPIPDSLGKDVADFISKLLVKDPRKRLGGGEGDAKELKK 340
Query: 310 HKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF-DVFDEEKIKDSP 355
H +F+ +DW+ + I PF P IRS D +NF + F + DSP
Sbjct: 341 HSFFKSLDWEKLARKEIPAPFKPVIRSELDVSNFSEEFTQMPPTDSP 387
Score = 122 bits (294), Expect = 1e-26
Identities = 79/250 (31%), Positives = 130/250 (52%), Gaps = 22/250 (8%)
Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVY 121
+ +LG G F + ++ TGK YA+K++ ++K + S + P +V
Sbjct: 451 EPILGDGTFSVCRKCVNLQTGKEYAVKIVSRKK-------DCSQEINLLRACQGHPNIVT 503
Query: 122 MKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYR 181
+ +D + Y VL ++ GGE+F +RK KF E+ A +++ A+ ++H+C +V+R
Sbjct: 504 LHDVIQDEAHTYLVLEYLKGGELFERIRKKSKFTESEASGILRKLVSAVSFMHSCGVVHR 563
Query: 182 DLKPENILI---DRTGYIKITDFGFCKLIRGR--TWTLCGTPEYLAPEIILS--KGYGMS 234
DLKPEN++ D + IK+ DFGF +L + + T C T Y APE++ +GY +
Sbjct: 564 DLKPENLVFTDDDDSAEIKVIDFGFARLKQEKESLHTPCFTLHYAAPEVLKGDPEGYDEN 623
Query: 235 VDWWSLGVLLFEMSAGHPPFFA----SDPMRIYEKIVAGKYRCPSH----FSVELKDIIG 286
D WSLGV+L+ M G PF A + I E+I G + S S E K ++
Sbjct: 624 CDLWSLGVILYTMLCGKAPFHARSRDENVSSIMERIKEGDFNFNSSAWTGVSNEAKSVVR 683
Query: 287 HVLQVDTTRR 296
+L V+ +R
Sbjct: 684 GLLTVNPGQR 693
>UniRef50_UPI000150AAA4 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 1025
Score = 211 bits (516), Expect = 2e-53
Identities = 106/317 (33%), Positives = 183/317 (57%), Gaps = 6/317 (1%)
Query: 40 QDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLK 99
Q+ V++ +S ++ F +LG G+FG V+LV+ +YYAMK+L+K K+++
Sbjct: 677 QNQVKTTSQNIQSKVTIHSFIIHSMLGKGSFGDVYLVQKKDNLQYYAMKVLQKSKMMKSN 736
Query: 100 QIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSA 159
I+++ E+ +L N PF+V + Y F+ L+ +L F AGG+M L+K+ E A
Sbjct: 737 VIKYALTERNVLSLSNHPFIVKLNYSFQTEEKLFLILDFAAGGDMGKLLQKVKVLSENDA 796
Query: 160 KFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK-----LIRGRTWTL 214
+ Y ++++L+LEYLH ++++RDLKP+NI+ID G+ +TDFG K G +
Sbjct: 797 RIYLSEILLSLEYLHKKDIIFRDLKPDNIVIDSEGHALLTDFGLSKEGVLDYTEGAK-SF 855
Query: 215 CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP 274
CG+ YLAPE++ +G+G +VDW+ GV+++EM G+PP++A+ ++ I P
Sbjct: 856 CGSIAYLAPEMLKRRGHGKAVDWYLFGVVMYEMLTGNPPYYANTKEDLFNNIQNAPLALP 915
Query: 275 SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI 334
S+ S E K ++ +L+ + R G ++ + KNH +F+ IDWD + +I P +
Sbjct: 916 SYLSQEAKSLLTALLERNPEMRLGCGRNDANEIKNHPFFKSIDWDMVYERKIKAPEVQLL 975
Query: 335 RSPGDTTNFDVFDEEKI 351
+ + N + F E I
Sbjct: 976 QLQLNNYNSEQFIETLI 992
>UniRef50_Q00X68 Cluster: Cyclic nucleotide dependent protein
kinase; n=3; Eukaryota|Rep: Cyclic nucleotide dependent
protein kinase - Ostreococcus tauri
Length = 1179
Score = 211 bits (516), Expect = 2e-53
Identities = 109/281 (38%), Positives = 175/281 (62%), Gaps = 9/281 (3%)
Query: 63 KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYM 122
K +G+G G VF+ K + T + +K++ K KI L Q ++ E +I+ + PF+
Sbjct: 412 KEIGSGMLGSVFIAKTLNTQETCCVKVMHKWKIAHLDQEKNVCRELEIMKRFDSPFLTRA 471
Query: 123 KYYFKDNVYLYYVLPFIAGGEMFSHL----RKMGKFEETSAKFYGAQVILALEYLHACEL 178
F+D LY ++ ++ GG++F L + G+F A+FY A+V +ALEY+H E
Sbjct: 472 VGAFQDARSLYLLMDYLPGGDLFQLLVSGPYRGGRFPVNVAQFYAAEVFIALEYIHTEEY 531
Query: 179 VYRDLKPENILIDRTGYIKITDFGFCK-LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVD 236
VYRDLKPEN+L+D G++K+TDFGFC+ L+ G R +T CGT +Y+APE++L++GY D
Sbjct: 532 VYRDLKPENVLLDACGHVKLTDFGFCRHLLPGERAYTTCGTADYMAPEVMLAQGYDQLAD 591
Query: 237 WWSLGVLLFEMSAGHPPFFA-SDPMRIYEKIVAGKYRCPS-HFSVELKDIIGHVLQVDTT 294
+WS GVLL+EM G+ PF + SD +R + +I++ + S +FS+ K +I + VD +
Sbjct: 592 YWSFGVLLYEMLVGYAPFASVSDGVR-HRRIISSDLKFHSTYFSLTAKSLISRLCVVDVS 650
Query: 295 RRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIR 335
+R G+ G D K+H +FR+++W+ + RI P P +R
Sbjct: 651 KRLGSGARGSGDLKSHDFFRDLNWEDVTARRIDSPVRPPVR 691
>UniRef50_A0BE58 Cluster: Chromosome undetermined scaffold_101,
whole genome shotgun sequence; n=17;
Oligohymenophorea|Rep: Chromosome undetermined
scaffold_101, whole genome shotgun sequence - Paramecium
tetraurelia
Length = 823
Score = 211 bits (516), Expect = 2e-53
Identities = 110/290 (37%), Positives = 164/290 (56%), Gaps = 9/290 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+D K LG G FG V+L K+ GK YA+K + K +IV H EK +L +
Sbjct: 495 LDDMIHIKKLGQGQFGSVYLCKNKKDGKLYALKCIIKNQIVEQHLENHLTQEKTVLEQVQ 554
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
FP ++ KD+ ++Y+++ +I G E+F +R +G ++FY A ++L +EYLH
Sbjct: 555 FPLMMRFYKSMKDDNFIYFLIEYIKGLELFDVIRDIGLLNTYDSQFYIASLLLCMEYLHT 614
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILSKGYGM 233
+VYRD+KPEN+++D GYI++ D G K++ +GRT+T+ GTP Y+APEI+ KGY
Sbjct: 615 HHIVYRDIKPENVMVDHHGYIRLIDMGTAKILKGKGRTFTIIGTPHYMAPEILNGKGYSY 674
Query: 234 SVDWWSLGVLLFEMSAGHPPFF--ASDPMRIYEKIVAGKYRCPSHF-SVELKDIIGHVLQ 290
SVD WS+G+ L+E G PF A DP IYE+I + P+H + K I +L
Sbjct: 675 SVDLWSIGICLYEFMCGGVPFAEDAEDPYEIYEEITKKQISYPNHLKDRKAKKFIDQLLN 734
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFF-PKIRSPGD 339
R G K + WF +DWD +++ + PP+ PK R GD
Sbjct: 735 KTPEIRLG---GSYAALKANTWFDGLDWDKLMDKELKPPYIPPKDRLIGD 781
>UniRef50_A4RL90 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 598
Score = 211 bits (516), Expect = 2e-53
Identities = 115/294 (39%), Positives = 171/294 (58%), Gaps = 7/294 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI-VRLKQIEHSYYEKKILCGLN 115
++FE+ + LG GA+G V LVK TG+ +A K L+K + V K ++ + E+++L +N
Sbjct: 223 DEFEQVRCLGKGAYGTVILVKQRSTGRLFAQKQLKKASLTVSKKYVQQAKTERQVLETVN 282
Query: 116 -FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PFVV + Y F+D+ LY +L + GGE+F HL F E A FY +++LAL +LH
Sbjct: 283 RHPFVVKLFYAFQDHEKLYLILEYGQGGELFHHLDTEKLFSEDVAAFYMGEMVLALFHLH 342
Query: 175 A-CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKG 230
+VYRDLKPEN L+D G++ +TDFG K+ + GT EY+APEIIL K
Sbjct: 343 QDLGVVYRDLKPENCLLDAEGHLLLTDFGLSKVAVDEDDHCNSFLGTIEYMAPEIILGKK 402
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y +VDWW+LG L ++ G+PPF ++ +I + IV K P S + KD++ +L+
Sbjct: 403 YSKAVDWWALGALGHDLMTGNPPFRGANHAKIQDNIVKQKLMLPYFMSSDAKDLLTRLLR 462
Query: 291 VDTTRRYGTLKDGVLD-FKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
D +R G+ L+ K H++FR+IDW + + PP P I P NF
Sbjct: 463 KDPAKRLGSQMPKDLNLIKKHRFFRKIDWVKLSKREMEPPIRPLITDPELAENF 516
>UniRef50_A2G3R6 Cluster: AGC family protein kinase; n=3;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 431
Score = 210 bits (514), Expect = 3e-53
Identities = 110/302 (36%), Positives = 168/302 (55%), Gaps = 8/302 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+ F+ VLG G +G V L + I +G+ +A+K + K+++ ++ E+ L +
Sbjct: 107 IESFKVLSVLGRGNYGKVMLAEKIDSGELFAIKSVHKKRLALAGKVHTMLSERNTLINAS 166
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + Y F++ Y VL ++ GGEMF+++ G A+ Y A+++ AL +LH
Sbjct: 167 NPFIVKLFYAFQNATKFYLVLEYVPGGEMFNYMSTNGAVPLEDARIYAAEIVTALHFLHQ 226
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR--TWTLCGTPEYLAPEIILSKGYGM 233
+++YRDLKPENIL+ + G+IK+TDFGF K + T T CGT EYLAPE+I YG
Sbjct: 227 NDIIYRDLKPENILLAQDGHIKLTDFGFAKDLSQSEVTKTFCGTNEYLAPEVISRVNYGP 286
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
+VDWW+LG+LL+EM PFF + R++ +I+ P ++ +I +LQ
Sbjct: 287 AVDWWTLGILLYEMLFQTTPFFHQNTSRMFTRILMDPVVFPKGADPDVCSLITGLLQKRD 346
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIK 352
+RY D H +F IDWD +L P + P I+S D +NFD F E
Sbjct: 347 RKRY-----AYEDIIKHPFFNGIDWDKVLTKSYVPSYKPPIKSKKDVSNFDQEFTAEPAM 401
Query: 353 DS 354
DS
Sbjct: 402 DS 403
>UniRef50_Q02956 Cluster: Protein kinase C zeta type; n=60;
Bilateria|Rep: Protein kinase C zeta type - Mus musculus
(Mouse)
Length = 592
Score = 210 bits (513), Expect = 4e-53
Identities = 114/313 (36%), Positives = 176/313 (56%), Gaps = 13/313 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGL 114
L DF+ +V+G G++ V LV+ + YAMK+++KE + + I+ EK +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L+ V+ ++ GG++ H+++ K E A+FY A++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+TD+G CK G T T CGTP Y+APEI+ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 232 GMSVDWWSLGVLLFEMSAGHPPF--FASDPMR-----IYEKIVAGKYRCPSHFSVELKDI 284
G SVDWW+LGVL+FEM AG PF +P +++ I+ R P SV+ +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 285 IGHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ L D R G + G D K+H +FR IDWD + + PPF P+I NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQITDDYGLDNF 548
Query: 344 DV-FDEEKIKDSP 355
D F E ++ +P
Sbjct: 549 DTQFTSEPVQLTP 561
>UniRef50_UPI00006A0EC2 Cluster: UPI00006A0EC2 related cluster;
n=16; Xenopus tropicalis|Rep: UPI00006A0EC2 UniRef100
entry - Xenopus tropicalis
Length = 584
Score = 210 bits (512), Expect = 6e-53
Identities = 110/279 (39%), Positives = 160/279 (57%), Gaps = 7/279 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL---CGLN 115
F +VLG G FG VFL +H T YA+K L K++++ ++ ++EK+IL N
Sbjct: 2 FNLGQVLGEGGFGKVFLAEHKNTEVLYAIKALRKDQVLEKGNLDSVFHEKEILQRVSSAN 61
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + F+ +L+YV+ ++ GG+MF +R + + EE FY A ++L LE LH
Sbjct: 62 HPFLVSLHGTFQTASHLFYVMEYLPGGDMFDFIRSV-ELEEPDVMFYTACIVLGLEALHQ 120
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGYG 232
+V+RDLK EN+L+DR GY+KI DFG K G RT T+CGT Y+APEI L GYG
Sbjct: 121 LGIVHRDLKLENLLLDRDGYLKIVDFGLSKDSFGYSDRTNTVCGTRTYMAPEIYLKLGYG 180
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
M+ DWW+LG+ ++ M PF DP+ I+ P S + +I +L+ D
Sbjct: 181 MAADWWALGITIYIMLLYELPFNNKDPVEQMSSILYDDIELPEDLSEDACTLIQELLEKD 240
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFF 331
R G+ G K H +FR++DWD +L RI P+F
Sbjct: 241 PEFRLGSGDAGAEMIKEHPFFRDMDWDHLLQRRITAPYF 279
Score = 176 bits (428), Expect = 9e-43
Identities = 93/225 (41%), Positives = 134/225 (59%), Gaps = 7/225 (3%)
Query: 42 FVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQI 101
F+ + + L+ F +VLG G FG VFL +H T YA+K L+KE ++ +
Sbjct: 338 FILFFSPVEPGSPSLDQFNLGQVLGEGGFGKVFLAEHKNTEVLYAIKALKKEHVLEKGNL 397
Query: 102 EHSYYEKKIL---CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETS 158
+ ++EK+IL N PF+V + F+ +L+YV+ ++ GG+MF +R + + EE
Sbjct: 398 DSVFHEKEILQTVSSSNHPFLVSLHGTFQTASHLFYVMEYLPGGDMFDFIRSV-ELEEPD 456
Query: 159 AKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLC 215
FY A V+L LE LH +V+RDLK EN+L+DR GY+KI DFG K G RT T+C
Sbjct: 457 VMFYTACVVLGLEALHQLGIVHRDLKLENLLLDRDGYLKIVDFGLSKDRFGYSDRTNTVC 516
Query: 216 GTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPM 260
GT Y+APEI L GYGM+ DWW+LG+ ++ M PF DP+
Sbjct: 517 GTRTYMAPEIYLKLGYGMAADWWALGITVYIMLLYELPFNNKDPV 561
>UniRef50_Q01E02 Cluster: CGMP-dependent protein kinase, putative;
n=2; Ostreococcus|Rep: CGMP-dependent protein kinase,
putative - Ostreococcus tauri
Length = 935
Score = 210 bits (512), Expect = 6e-53
Identities = 105/293 (35%), Positives = 166/293 (56%), Gaps = 5/293 (1%)
Query: 54 AKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG 113
A L++ E LG G+FG V LV + G+ YA+K + K ++V +EH + EK+ +
Sbjct: 619 ATLDELETVGFLGVGSFGRVTLVSY--QGETYALKEIGKAQVVSRGLVEHVWREKETMAQ 676
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLR-KMGKFEETSAKFYGAQVILALEY 172
+ PF+V + + + ++ ++ + GGE+F++L+ + E KFY A V+ A EY
Sbjct: 677 CDSPFLVNLHRTYVNEKSIFMLMDKVLGGELFTYLQMRNAPLPEAHGKFYAACVVSAFEY 736
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK-LIRG-RTWTLCGTPEYLAPEIILSKG 230
LH ++YRDLKPEN+LI GY+K+TDF F K L +G +T+TLCGTP+YLAPE + G
Sbjct: 737 LHDRNIIYRDLKPENLLISTNGYLKVTDFSFAKKLQKGQKTFTLCGTPQYLAPEQVQQVG 796
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ +VDWW+LGVL++E+ G PPF D Y+ I + + + ++ +L
Sbjct: 797 HNRAVDWWALGVLIYELVNGLPPFNQDDDYARYKAINDVSFHFSPKNAPAFRSVVSGLLL 856
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
R G K G D K H WF +++W ++ R P+ P++ D +F
Sbjct: 857 RLPAGRLGMGKSGARDIKQHPWFADVNWSAMAQQRARAPYIPRVDDISDLRHF 909
>UniRef50_Q9VL34 Cluster: CG4839-PA, isoform A; n=2; Sophophora|Rep:
CG4839-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 1003
Score = 210 bits (512), Expect = 6e-53
Identities = 102/301 (33%), Positives = 175/301 (58%), Gaps = 7/301 (2%)
Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107
D S +++ ++ LG GAFG V LV + + A+K+++K ++V+ QIEH Y E
Sbjct: 683 DNEYSQVAISELKKIATLGCGAFGRVDLVAY--NQQALALKIIKKIEVVKQDQIEHVYNE 740
Query: 108 KKILCGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166
K ++ PF+V + ++++ Y+Y+++ GG++++ + K F+E +AKF V
Sbjct: 741 KNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCV 800
Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR--GRTWTLCGTPEYLAPE 224
+ A +YLH+ +YRDLKPEN+++ GY K+ DFGF K +R +T T GTPEY+APE
Sbjct: 801 VEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNEKTNTFAGTPEYVAPE 860
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELK 282
IIL +G+ +VD+W+LG+L++E+ G PF + ++IY++I++G PS +
Sbjct: 861 IILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKSAQ 920
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ H+ + R G + G+ D K H WF +DW + ++ P ++S D
Sbjct: 921 HLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWTDLQY 980
Query: 343 F 343
F
Sbjct: 981 F 981
>UniRef50_A2ECT2 Cluster: AGC family protein kinase; n=3;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 437
Score = 210 bits (512), Expect = 6e-53
Identities = 109/304 (35%), Positives = 168/304 (55%), Gaps = 8/304 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+N FE V+G G +G V LVK TG+ +A+K + K K+++ +I E+ IL N
Sbjct: 107 MNCFEIISVIGKGCYGKVRLVKSKSTGEVFAIKSIRKSKLIQQNRIHTVIAERNILSKAN 166
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V +++ F+ Y L ++ GGE+++ + + G + K AQ+ +AL YLH+
Sbjct: 167 HPFIVALRFAFQTPAKFYLGLEYVPGGELYTRIHRDGYLSKMEYKMVIAQIAIALNYLHS 226
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTWTLCGTPEYLAPEIILSKGYGM 233
+VYRD+KPENILI GYIK+ DFG K + +T + CGTP+Y+APE I+ Y
Sbjct: 227 IGIVYRDIKPENILIGADGYIKLADFGLAKDIITDNKTTSFCGTPKYIAPETIVGVPYDQ 286
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
SVDWWSLG+L +++ PF++ + +Y I+ K P S E D I +L+ D
Sbjct: 287 SVDWWSLGILTYQLIYHKFPFYSQNVDAVYRMILNKKVEFPDSASPEEIDFISILLEKDP 346
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIK 352
+R G + H +F E ++ ILN ++ P + P + P + FD +F E
Sbjct: 347 KKR-----AGYNEVSQHPFFSEFTFEDILNKKLTPEYIPNLEEPTEVKYFDPIFTSEIKA 401
Query: 353 DSPV 356
DS V
Sbjct: 402 DSYV 405
>UniRef50_P43057 Cluster: Protein kinase C-like 1; n=4;
Saccharomycetales|Rep: Protein kinase C-like 1 - Candida
albicans (Yeast)
Length = 1097
Score = 210 bits (512), Expect = 6e-53
Identities = 113/308 (36%), Positives = 176/308 (57%), Gaps = 8/308 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+DF+ VLG G FG V L + T K A+K+L+K+ IV + E EK++ N
Sbjct: 767 LDDFQFLAVLGKGNFGKVMLAESRHTSKLCAIKVLKKDFIVENDEAESVKSEKRVFLTAN 826
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF++ + F+ +Y+V+ +I+GG++ H++K +F AKFY +V+L L+Y
Sbjct: 827 KEMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHIQK-NRFTAKRAKFYACEVLLGLKY 885
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSK 229
H +VYRDLK +NIL+ G+IKI D+G CK + T T CGTPE++APEI+ K
Sbjct: 886 FHDNGIVYRDLKLDNILLTTKGHIKIGDYGLCKEDMWHKSTTSTFCGTPEFMAPEIVAGK 945
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y SVDWW+ GVLLF+M PF D I+ I + + P + S + ++ +L
Sbjct: 946 AYDRSVDWWAFGVLLFQMLLCQSPFKGDDEDDIFNAIENDEVKYPINLSRQTVLVLQALL 1005
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDE 348
D ++R G+ + H +F ++++D +LN RI P+ P+++S D +NFD F
Sbjct: 1006 TKDPSQRLGSGPKDAEEIMEHPYFHDVNFDDVLNCRIPAPYIPEVQSEHDYSNFDKEFTS 1065
Query: 349 EKIKDSPV 356
E + +PV
Sbjct: 1066 ETPRLTPV 1073
>UniRef50_A0CP93 Cluster: Chromosome undetermined scaffold_23, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_23,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 618
Score = 209 bits (511), Expect = 8e-53
Identities = 115/299 (38%), Positives = 171/299 (57%), Gaps = 7/299 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHI-VTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+ F K LG GAFGIV+LVK YAMK+L KEKI + K + + EK IL ++
Sbjct: 308 DSFTYHKELGKGAFGIVYLVKKKDEQNSLYAMKVLRKEKISQ-KLLPYIQTEKSILSVID 366
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + Y F+ L+ V+ F GG++ L + E AK Y A++ILA+E LH
Sbjct: 367 HPFIVKLHYAFQTQHKLFLVMDFCPGGDLTKLLDLKSRLSEQVAKMYTAEIILAIEALHQ 426
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTWTLCGTPEYLAPEIILSKGYGM 233
+++YRDLKP+NI+ID G+ +TDFG K + T + CGTP Y+APE++ K Y
Sbjct: 427 NKIMYRDLKPQNIIIDNKGHCMLTDFGLAKTDIENENTKSFCGTPAYMAPEVVNRKFYNR 486
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP-SHFSVELKDIIGHVLQVD 292
SVDW+ LG + EM G PP+++ + ++E I + + P ++ S E I +L+ +
Sbjct: 487 SVDWYQLGTITHEMLFGMPPYYSHNREELFENIKNKQLKFPQNNLSKEALSFIQQLLERN 546
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKI 351
T+R G KD + K H WF +I+WD +N ++ P P I + + T FDE+ I
Sbjct: 547 PTKRLGAKKDSE-EVKAHPWFSDINWDLAINKKLPVP-MPSIMNQANQTLQVNFDEDSI 603
>UniRef50_A5DM82 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1047
Score = 209 bits (511), Expect = 8e-53
Identities = 116/308 (37%), Positives = 176/308 (57%), Gaps = 8/308 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L+DF+ VLG G FG V L + T A+K+L+K+ IV + E EK++ N
Sbjct: 717 LDDFQFLAVLGKGNFGKVMLAESRQTQTLCAIKVLKKDFIVENDEAESVKSEKRVFLTAN 776
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF++ + F+ +Y+V+ +I+GG++ H++K +F AKFY +V+LAL+Y
Sbjct: 777 KAMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHIQK-SRFSAKRAKFYACEVLLALKY 835
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSK 229
H +VYRD+K +NIL+ G+IKI D+G CK + +G T T CGTPE++APEII K
Sbjct: 836 FHENGIVYRDIKLDNILLTTKGHIKIGDYGLCKENMWQGNTTATFCGTPEFMAPEIISGK 895
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW+LGVLLF+M PF D I+ I R P + + ++ +L
Sbjct: 896 QYDRAVDWWALGVLLFQMLLCQSPFKGDDEDEIFNAIEHDDVRYPINMPRQTVLVLQALL 955
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDE 348
D R G+ + +H +F ++++D ILN R+ PP+ P+I S D +NFD F
Sbjct: 956 TKDPLSRLGSGPRDAEEIMDHPYFSDVNFDDILNLRVQPPYIPEITSEHDYSNFDKEFTS 1015
Query: 349 EKIKDSPV 356
E + +PV
Sbjct: 1016 ETPRLTPV 1023
>UniRef50_UPI0000D562F1 Cluster: PREDICTED: similar to CG3324-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG3324-PA - Tribolium castaneum
Length = 636
Score = 209 bits (510), Expect = 1e-52
Identities = 119/328 (36%), Positives = 181/328 (55%), Gaps = 18/328 (5%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGK---YYAMKMLEKEKIVRLKQIEHSYYEK 108
++ L+DF LG G FG V LV+H +GK +A+K ++K I K E + EK
Sbjct: 311 TDLNLSDFHVISTLGIGGFGRVELVQH--SGKKELVFALKCMKKYVIAAQKHQELVFNEK 368
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGK--FEETSAKFYGAQV 166
I F+V + ++D +LY++L GG++++HL K +E AKFY A V
Sbjct: 369 NIQIVCKNNFIVRLYRTYRDKKFLYFLLEPCLGGDLWTHLYKQKPRFLDENHAKFYTACV 428
Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR------GRTWTLCGTPEY 220
+ A YLH ++YRDLKPEN+LID GY+K+TDFGF K ++ +T+T GTPEY
Sbjct: 429 VEAFNYLHERLIIYRDLKPENLLIDAKGYVKLTDFGFAKKLKMIKKCVKKTYTFAGTPEY 488
Query: 221 LAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDP--MRIYEKIVAG--KYRCPSH 276
+ PEI+L++G+ +VD+W+LGV +FE+ G PF D M+ Y+ I+ G P H
Sbjct: 489 VPPEIMLNQGHDKAVDYWALGVFVFELLTGKTPFRTDDVTYMKTYKLILKGIDDVEFPKH 548
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
SVE ++ + + +R G G+LD K H+WF DW ++ PF P +R+
Sbjct: 549 VSVEAVKLVKELCKSTPPQRLGCGSGGILDVKGHEWFGGFDWGRFEGGKMPAPFRPNLRT 608
Query: 337 PGDTTNFDVFD-EEKIKDSPVCLYEEEF 363
D F+ F +E + +++EF
Sbjct: 609 NIDVHYFEKFGADEDVPPDVAVDWDKEF 636
>UniRef50_A2FDD2 Cluster: AGC family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 436
Score = 209 bits (510), Expect = 1e-52
Identities = 105/287 (36%), Positives = 162/287 (56%), Gaps = 7/287 (2%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
+E ++ F VLG G +G V LV+ + TGK YA+K + K+K++ + Q++ E+
Sbjct: 107 TEHGYSMDQFRIISVLGRGFYGKVMLVEKLDTGKLYALKTVRKKKLIEMGQVDTIIAERN 166
Query: 110 ILCGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF++ ++ F+ Y L + AGGE+ HL + K Y A+V+L
Sbjct: 167 LLFSIPPHPFIISAEFAFQTPSKFYIGLEYAAGGELLHHLSNLPVVPIEDTKLYMAEVVL 226
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR-TWTLCGTPEYLAPEIIL 227
AL++LH +VYRDLKPEN+L+D++G++K+TDFG CK I T CGT EYLAPE++L
Sbjct: 227 ALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCKEITEEGAKTFCGTAEYLAPEVVL 286
Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGH 287
GYG VDWW+LGVLL+E+ PF+ + +++ IV + P D+I
Sbjct: 287 RLGYGFKVDWWALGVLLYEILFAGTPFYDDNQAVLFDNIVNEEPNYPKFGHKAAIDLIKL 346
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI 334
+LQ + R K H +F+ IDWD +L + P F ++
Sbjct: 347 LLQKEPENR-----PDFEQIKEHAFFKGIDWDKVLRKEVQPKNFRQV 388
>UniRef50_A2E8U1 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 417
Score = 209 bits (510), Expect = 1e-52
Identities = 113/310 (36%), Positives = 166/310 (53%), Gaps = 11/310 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++DF +G G +G V L K TG YA+K L K+K+V +++I E+ IL +
Sbjct: 100 IDDFTILDEIGNGQYGKVKLAKKKDTGDLYAIKTLHKQKLVEMQKIHTIMCERNILSKAS 159
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + Y F+ + Y + ++ GG +F H+R G + K Y A++ +AL +LH
Sbjct: 160 CPFIVQLHYAFQSDTKFYLCMEYVPGGTLFDHMRLSGTIPPDALKLYTAELAIALHHLHV 219
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILSKGYGM 233
+VYRDLKPEN+L+D G+IK+TDFG K I G + CGTP+Y+APEI+ K Y
Sbjct: 220 NHIVYRDLKPENVLLDEDGHIKLTDFGSSKQIDESGTLHSFCGTPDYIAPEIVEGKPYTS 279
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
VDWWSLG+L++EM PPF++ +P R Y+KIV G P L +I +L D
Sbjct: 280 KVDWWSLGILIYEMVFKAPPFYSVNPKRTYDKIVNGNIIFPGVVDENLVSLIRGLLNKDP 339
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKD 353
RR+ G + H + + +L P F P S + +V D I+D
Sbjct: 340 MRRF-----GYNEVMYHPLLSGFEINGLLKRAYTPNFLP---SSASAESIEVID-NSIRD 390
Query: 354 SPVCLYEEEF 363
S + EF
Sbjct: 391 SLGSNVDSEF 400
>UniRef50_A2E224 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 451
Score = 209 bits (510), Expect = 1e-52
Identities = 108/291 (37%), Positives = 166/291 (57%), Gaps = 11/291 (3%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+ + ++DF + LG+G +G V L +H + K YA+K + K ++V +I + E+ I
Sbjct: 99 QKSLSISDFRIIRTLGSGFYGKVLLAEHKQSKKIYAIKSIHKSRLVNDDKINTIFSERNI 158
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
L PF+V +K+ F+++ Y L +++GGE+F + +FY +V LAL
Sbjct: 159 LLLSQHPFIVGIKFSFQNDKKFYLGLEYVSGGELFKLIETGHCVPFQQVRFYVMEVALAL 218
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI------RGRTWTLCGTPEYLAPE 224
+YLH+ ++YRDLK EN+L+ ++G+IK+TDFG K++ T T CGTPEYLAPE
Sbjct: 219 DYLHSIGVIYRDLKLENVLMTKSGHIKLTDFGLSKIVADGKADNSTTSTFCGTPEYLAPE 278
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
+ILSK YG+ +DWW+LGV +E S PF + Y+ I+ + + P + L
Sbjct: 279 MILSKDYGIEIDWWALGVFTYEFSYTITPFVGKTNKKTYDNILHEEPKFPPNADPNLVSF 338
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIR 335
I L+ D T+R T K D K H +F I WD +LN +I PP PK +
Sbjct: 339 IMMCLRKDPTKR-ATFK----DIKKHPFFEGISWDDVLNKKITPPRKPKAK 384
>UniRef50_O96942 Cluster: Serine /threonine protein kinase; n=1;
Rhabdocalyptus dawsoni|Rep: Serine /threonine protein
kinase - Rhabdocalyptus dawsoni (boot sponge)
Length = 697
Score = 208 bits (509), Expect = 1e-52
Identities = 113/298 (37%), Positives = 174/298 (58%), Gaps = 9/298 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHI-VTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
L ++ VLG GAFG VF+ + +T + +A+K++ KE + ++ + EK +L
Sbjct: 345 LEQYKLLGVLGKGAFGKVFMAESSDLTEEIFALKVMHKELVFDFDAVDCTMMEKLVLALE 404
Query: 115 NF---PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+ +K F+D LY V+ F++GG++ HL K +F + +KFY A++ LA+
Sbjct: 405 DKNKPPFLTALKASFQDQENLYMVMEFLSGGDLLFHLLKSIRFTDERSKFYIAEISLAIF 464
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR--TWTLCGTPEYLAPEIIL 227
+LH+ E++YRDLKP+N+L+ G+IK+ DFG CK + G+ T T CGT +Y+APEI+
Sbjct: 465 FLHSKEIIYRDLKPDNVLLSAEGHIKLADFGLCKEGIKNGKSTTRTYCGTLDYMAPEILQ 524
Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGH 287
K Y +VD WSLGV+L+EM AG PF A + I P++FS E +I
Sbjct: 525 RKDYDNAVDMWSLGVMLYEMLAGRTPFDARTEEMVVTNIKNRAPSFPNNFSKEAIKLITV 584
Query: 288 VLQVDTTRRYG-TLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+L+ R G DG F+ +K+F +IDWD + ++ PPF P I+ T NFD
Sbjct: 585 LLKKVPKERLGFDPVDGQKQFQANKYFSDIDWDMLNKQQVEPPFIPTIKGKKSTANFD 642
>UniRef50_A2EEZ5 Cluster: AGC family protein kinase; n=2;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 417
Score = 208 bits (509), Expect = 1e-52
Identities = 108/299 (36%), Positives = 168/299 (56%), Gaps = 7/299 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF VLG G +G V L + T + YA+K + K+ +V +++++ E+ +L ++ P
Sbjct: 105 DFRIISVLGRGYYGKVMLCEENTTKELYAIKTIHKKMLVNSDKVQNALTERNVLVRVHHP 164
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F+V +K F+ LY+ + + GGE+F HL + G F + Y A++ LA+EYLH
Sbjct: 165 FIVSLKTTFQTPTKLYFAMEYAPGGELFFHLERKGAFHIHDVRIYVAELALAIEYLHDNN 224
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCK-LIRGRTWTLCGTPEYLAPEIILSKGYGMSVD 236
++YRD+KPENIL+D G++KITDFG K + T TLCG+P Y+APEII YG +VD
Sbjct: 225 IIYRDIKPENILLDSEGHVKITDFGLSKEMEEDTTSTLCGSPNYMAPEIITHTRYGPAVD 284
Query: 237 WWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR 296
WWSLG+L++EM G PF + + I + P + + + + +I +LQ + + R
Sbjct: 285 WWSLGILMYEMLFGVQPFVNENKSVLLMMIATCRVSFPRNANPDAQSLILGLLQKNPSER 344
Query: 297 YGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEKIKDS 354
+ G K+H +F+ D+D L ++ P F P D NF F +E DS
Sbjct: 345 F-----GFEQIKSHPFFQGRDFDDYLQKKVKPIFVPISLRRTDPVNFSTEFTQETPTDS 398
>UniRef50_UPI000065FBEC Cluster: Ribosomal protein S6 kinase alpha-5
(EC 2.7.11.1) (Nuclear mitogen- and stress-activated
protein kinase 1) (90 kDa ribosomal protein S6 kinase 5)
(RSK-like protein kinase) (RSKL).; n=1; Takifugu
rubripes|Rep: Ribosomal protein S6 kinase alpha-5 (EC
2.7.11.1) (Nuclear mitogen- and stress-activated protein
kinase 1) (90 kDa ribosomal protein S6 kinase 5)
(RSK-like protein kinase) (RSKL). - Takifugu rubripes
Length = 807
Score = 208 bits (508), Expect = 2e-52
Identities = 120/318 (37%), Positives = 185/318 (58%), Gaps = 15/318 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYYEKKIL 111
+ +FE KVLGTGA+G VFLV+ + GK YAMK+L+K IV + K EH+ E+++L
Sbjct: 22 IENFELLKVLGTGAYGKVFLVRKVSGHDAGKLYAMKVLKKATIVQKAKTAEHTRTERQVL 81
Query: 112 CGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ PF+V + Y F+ + L+ +L ++ GGE+F+HL + +F+E Y +++LAL
Sbjct: 82 EHIRQSPFLVTLHYAFQTDTKLHLILDYVNGGELFTHLVQRVRFKEQEVALYSGEIVLAL 141
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR--GRTWTLCGTPEYLAPEIILS 228
E+LH +VYRDLK ENIL+D +G+I +TDFG K R +++CGT EY+APEI+
Sbjct: 142 EHLHKLGVVYRDLKLENILLDSSGHIVLTDFGLSKEFDQVERAFSVCGTIEYMAPEIVEG 201
Query: 229 KGYG---MSVDWWSLGVLLFEMSAGHPPFFA----SDPMRIYEKIVAGKYRCPSHFSVEL 281
G + +DWWSLGVL++E+ G PF + I ++I+ P
Sbjct: 202 GESGHDKVILDWWSLGVLMYELLTGGSPFTVDGDNNSHTDIAKRILKKDPPFPKDLGPLA 261
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
KDII +L D +R G+ +G + K ++++I+W+ + ++ PF P IR D +
Sbjct: 262 KDIIQRLLVKDPKKRLGSGPNGAENVKKRPFYQKINWEDLAAKKVPAPFKPVIRDELDVS 321
Query: 342 NF-DVFDEEKIKDSPVCL 358
NF + F E SP L
Sbjct: 322 NFAEEFTEMDPTYSPAAL 339
Score = 99.1 bits (236), Expect = 2e-19
Identities = 64/184 (34%), Positives = 93/184 (50%), Gaps = 17/184 (9%)
Query: 130 VYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENIL 189
++ Y VL + GGE+ +R+ F ET A +++ A+ ++H +V+RDLKPEN+L
Sbjct: 529 LHTYLVLELLGGGELLERIRRKQHFSETEASRIMRKLVSAVSHMHDVGVVHRDLKPENLL 588
Query: 190 I---DRTGYIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGYGMSVDWWSLGVL 243
IKI DFGF +L L C T +Y APEI+ GY S D WSLGV+
Sbjct: 589 FTDESENSEIKIIDFGFARLKPPDNQLLKTPCFTLQYAAPEILKYDGYDESCDLWSLGVI 648
Query: 244 LFEMSAGHPPFFA-------SDPMRIYEKIVAGKYRCPS----HFSVELKDIIGHVLQVD 292
L+ M +G PF + I +KI G + + S + KD+I +L VD
Sbjct: 649 LYTMLSGQVPFQCQGKSLTHTSAEEIMKKIKQGDFSFEGEAWRNVSQQAKDLIQELLTVD 708
Query: 293 TTRR 296
+R
Sbjct: 709 PNKR 712
>UniRef50_A0EIN6 Cluster: Chromosome undetermined scaffold_99, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_99,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 603
Score = 208 bits (508), Expect = 2e-52
Identities = 110/324 (33%), Positives = 185/324 (57%), Gaps = 8/324 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
+S+SN+ +DF K +G G F V+LV+ G+++AMK+++K I++ + EK
Sbjct: 173 ESKSNS-FDDFTLIKCIGVGGFSRVYLVRQKRNGQFFAMKIIDKSFIIKNNKESMINNEK 231
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
I+ L+ F+ + F+ YL +V+ + GGE+F HLRKMG E AK Y Q+ L
Sbjct: 232 WIMSNLDSQFLTRLHCSFETKYYLVFVMDYCHGGELFFHLRKMGTLSEEVAKQYFGQLCL 291
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEI 225
A+ YLH ++YRDLKPENIL+D GYIK++DFG K + R + T++ CG+PEY++PE+
Sbjct: 292 AIHYLHEQNVIYRDLKPENILLDIDGYIKLSDFGLSKPNISRDKQTYSFCGSPEYMSPEM 351
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSV--ELKD 283
+ +G+ +D +SLG +L+E G+PP++ I I K P H + +LK+
Sbjct: 352 VSKRGHNQLLDCYSLGAVLYEFIYGYPPYYDQQLQNILNSIQYDKLEFPEHIKISDQLKN 411
Query: 284 IIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK-IRSPGDTTN 342
++ ++L D R G + +G+ D NHKW ++ ++ +++ + P+ +++ +
Sbjct: 412 LLLNLLTKDQNERLGRM-NGIEDVLNHKWLSNFNYTALYKKQLNIQYKPQPLQTNYNVAE 470
Query: 343 FDVFDEEKIKDSPVCLYEEEFADF 366
F D E + LY E+ F
Sbjct: 471 FSKGDREFQQKLQDNLYREQKTKF 494
>UniRef50_UPI00006CFE83 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 890
Score = 207 bits (506), Expect = 3e-52
Identities = 105/277 (37%), Positives = 164/277 (59%), Gaps = 5/277 (1%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF LG G+FG VFLV+ T + +AMKML+K ++ +Q++++ E IL P
Sbjct: 572 DFTILGALGKGSFGRVFLVQQNSTEELFAMKMLKKVSLIMKRQLKYAVTECNILKRCKNP 631
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
FVV + Y F+ +LY VL + GG + H+++ +F E +A+F+ ++ILA+EYLH+
Sbjct: 632 FVVGLHYAFQTPNHLYMVLDYCNGGVLLQHIQRESRFSELTARFFVCEIILAIEYLHSQN 691
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKGYGMS 234
++YRDLKPENILI G+IK+TDFG K T + CG+P YL+PE++L KG+ +
Sbjct: 692 ILYRDLKPENILISSDGHIKLTDFGLSKEHVADFDVTKSFCGSPAYLSPEMLLGKGFSKA 751
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTT 294
D + +G +L+EM G PPFF D ++Y I + + P + S K +I +L+ +
Sbjct: 752 SDIYGIGCVLYEMLTGQPPFFHEDIKQLYSGIKSEDPQLPKYLSNSAKTLIIQLLKKNPK 811
Query: 295 RRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFF 331
R G + + K+H++F IDW + + PP F
Sbjct: 812 ERLG--YNSIQQIKSHEFFEGIDWHRVYEKQYQPPQF 846
>UniRef50_A0DDH0 Cluster: Chromosome undetermined scaffold_46, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_46,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 344
Score = 207 bits (506), Expect = 3e-52
Identities = 107/279 (38%), Positives = 172/279 (61%), Gaps = 12/279 (4%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L DF++ K LG GA+G VFLV+H ++YAMK + K +I + +H E++IL
Sbjct: 30 RLQDFKKLKKLGQGAYGSVFLVEH--KNEFYAMKEIAKSRIQKKSTKQHIDSERQILQCT 87
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
++V +KY F+D+ LY V+ ++ GGE+F H+R+ G F KFY AQ+++AL LH
Sbjct: 88 KSKYLVELKYAFQDDRNLYMVVNYVKGGELFFHIREAGSFTLEICKFYSAQILMALLELH 147
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS-KGY 231
++YRDLKPENIL+D G++ +TDFG K + T ++CGTPEYLAPEII S GY
Sbjct: 148 NQNIIYRDLKPENILLDEQGHVVLTDFGLSKHLCDDELTKSMCGTPEYLAPEIITSNNGY 207
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
VD++SLG +++EM G PF++++ ++++ + K P ++ +L++
Sbjct: 208 SFEVDYYSLGCIIYEMLNGKTPFYSTNKRQMFQDRLTRKVTWPDSIDETAISLVNGLLEI 267
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPF 330
D +R L+ + K HK+F +I++D + N + PP+
Sbjct: 268 DPLKR---LQGD--EIKKHKFFEDINFDELRN--VKPPY 299
>UniRef50_A0CSN3 Cluster: Chromosome undetermined scaffold_26, whole
genome shotgun sequence; n=6; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_26,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 774
Score = 207 bits (506), Expect = 3e-52
Identities = 104/298 (34%), Positives = 175/298 (58%), Gaps = 5/298 (1%)
Query: 40 QDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLK 99
+ ++S + ++ L DFE + +G G F V+LV+ TG++YAMK++EK+ I++
Sbjct: 359 EPIIDSEQELKQTRVSLRDFEFIRCIGVGGFSKVYLVREKRTGQFYAMKLVEKKPIMQQN 418
Query: 100 QIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSA 159
+ E+ I+ LN PF+V M+Y F+ YL +VL + +GGE+F LRK+ K E A
Sbjct: 419 KQNIIQNERDIMSQLNHPFIVKMQYAFESRKYLVFVLEYCSGGELFYLLRKVKKMSEEEA 478
Query: 160 KFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCG 216
FY A++ L ++ LH ++YRD+KPENILID G+++I DFG K + ++ CG
Sbjct: 479 FFYFAEICLGMKNLHDNNIIYRDIKPENILIDFEGHVRIADFGLSKPQMENQDIAYSFCG 538
Query: 217 TPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH 276
+PEY+APE++L +G+ +D + LG LL+E+ G PPF++ + +Y+KI+ K PS
Sbjct: 539 SPEYMAPEMLLKQGHTFQLDLYCLGALLYELITGLPPFYSRNTDEMYQKILNQKLSFPSQ 598
Query: 277 FSVE--LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
+ LKD++ +L +R ++ + +W + + L +++PPF P
Sbjct: 599 LQMSQLLKDLLSSLLAKTPNKRIDDIESLLKHPWMTQWSDKNLYKDFLMKKVNPPFKP 656
>UniRef50_UPI00006CD5AE Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 779
Score = 207 bits (505), Expect = 4e-52
Identities = 105/301 (34%), Positives = 174/301 (57%), Gaps = 8/301 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF LG G+FG V+LV+ K +AMK+ K+++V+ + EKK L N P
Sbjct: 453 DFRFISKLGQGSFGEVYLVER--EKKLFAMKIQNKQQVVQKNLQRYVQTEKKALSLFNHP 510
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F++ + Y F+++ YL+ V+ + GG+M ++L K K E A+ Y AQ++LALE LH +
Sbjct: 511 FIIKLHYAFQNDWYLFMVMEYAEGGDMGNYLNKRNKLPEDEARIYTAQIVLALEELHKQD 570
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWT--LCGTPEYLAPEIILSKGYGMS 234
+++RDLKP+N+++D G K+TDFG K I+ T+T CG+ YLAPE++ + + +
Sbjct: 571 IIFRDLKPDNVVLDHLGNAKLTDFGLSKEGIKENTFTKSFCGSVAYLAPEVLAKRPHSRT 630
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTT 294
VDW+ LG L+E+ G PP++ ++ +Y+ I G + P S + KD+I +L +
Sbjct: 631 VDWYLLGTFLYELLVGIPPYYDNNKEILYDNIRRGPLKIPRSMSADAKDLIKQLLNRNPK 690
Query: 295 RRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFF--PKIRSPGDTTNFDVFDEEKIK 352
R G+ +D + K H++F+ I W+ I ++ P F PK+ + TN + + K
Sbjct: 691 ERLGSKRDSE-EIKEHQFFKNICWNDIYTGKVKAPSFDVPKVDTKPTLTNINFDNRPKQS 749
Query: 353 D 353
D
Sbjct: 750 D 750
>UniRef50_A2DW86 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 423
Score = 207 bits (505), Expect = 4e-52
Identities = 105/306 (34%), Positives = 168/306 (54%), Gaps = 8/306 (2%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
S ++DF+ VLG G +G V L T +A+K + K ++V K++ + E+ +L
Sbjct: 100 SGITMDDFDVISVLGRGFYGKVMLCHKKNTNDIFAIKTVHKNRLVSAKKVHTIFTERNVL 159
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
PF+V +K+ F+ + +Y L + GGE+F HL+K G F + Y A++ LAL+
Sbjct: 160 MKAQHPFIVSLKFAFQTDTKVYLGLEYAPGGELFYHLQKFGSFPIDDVRIYIAEMALALD 219
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILSK 229
+LH ++YRD+KPENIL+D G++K+TDFG K + T T CGT EY+APE++
Sbjct: 220 FLHKHGVIYRDIKPENILLDAQGHVKLTDFGLAKDLTDESSTTTFCGTFEYMAPEVVARS 279
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
YG ++DWW+LG+L +E+ GH PF + + ++ I + P+ D I ++L
Sbjct: 280 SYGPAIDWWALGILTYELLNGHSPFQSDNRALLFMSIRTQPPKFPARTDRNTIDFISNLL 339
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDE 348
D RY G+ + H +F +++D +L + P F P I + NFD F
Sbjct: 340 NKDPELRY-----GMDQIRTHPFFNGMNFDDVLEKKYKPSFVPTIPNDVAALNFDSEFTC 394
Query: 349 EKIKDS 354
E +DS
Sbjct: 395 EPAQDS 400
>UniRef50_UPI00006CFF91 Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 987
Score = 206 bits (504), Expect = 5e-52
Identities = 108/309 (34%), Positives = 172/309 (55%), Gaps = 5/309 (1%)
Query: 24 SPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGK 83
SP+ Q+ ++ +D + F+ KVLG G+FG VFL K +G
Sbjct: 636 SPSSQDNSTRSTSVSPEDPNVDLGSLQDEKVTFESFQILKVLGAGSFGKVFLAKKKDSGN 695
Query: 84 YYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGE 143
YA+K L+K ++ +Q+ ++ E +L N PF++ + Y + YLY VL + +GG+
Sbjct: 696 IYAIKALKKRPLIMKRQLRYAVTEANVLKMCNHPFILGLHYALQTPNYLYLVLDYCSGGD 755
Query: 144 MFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGF 203
+ SHL +F E A FY A+++LA++++H ++VYRDLKPENILI G+IK+ DFG
Sbjct: 756 ISSHLAYKRRFSEEEALFYIAELVLAIQHIHEKDVVYRDLKPENILIASDGHIKLADFGL 815
Query: 204 CK---LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPM 260
K + +T + CGTP YL+PE++ +KG + D + +G +L+EM G PP++ D
Sbjct: 816 SKDNVTDQSKTKSFCGTPAYLSPEMLNNKGATKASDLYGIGAVLYEMLTGDPPYYNDDIP 875
Query: 261 RIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDS 320
+Y+KI G PS+ S + ++II +L + R G L K +F IDW+
Sbjct: 876 TMYKKIKEGNLTYPSYVSQKARNIINGLLDRNPKTRLGAQDREQL--KRDPFFEGIDWEK 933
Query: 321 ILNSRIHPP 329
+ N + PP
Sbjct: 934 LYNKQYKPP 942
>UniRef50_UPI0000519F68 Cluster: PREDICTED: similar to
cGMP-dependent protein kinase 21D CG3324-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to cGMP-dependent
protein kinase 21D CG3324-PA - Apis mellifera
Length = 639
Score = 206 bits (504), Expect = 5e-52
Identities = 122/339 (35%), Positives = 187/339 (55%), Gaps = 13/339 (3%)
Query: 21 GGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLV--KH 78
GG K +++ Y K + D +W+ K + L+D E + +G G++G V LV K
Sbjct: 295 GGMESIKNKKWHAYEKLIVPD---NWN-KQFAKLTLSDLESEGTIGVGSYGRVELVIVKS 350
Query: 79 IVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPF 138
+++ +A K ++K I R Y EK L + PF+ + FKD YLY+++
Sbjct: 351 LMSNFSFARKKVKKHVITRGGFQTMIYNEKNNLKICDSPFICKLYKTFKDKKYLYFLMEV 410
Query: 139 IAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKI 198
GG++ + L + G++ +++F A ++ A YLH+ ++YRDLKPENI+I+ GYIK+
Sbjct: 411 GLGGDLRTALYRHGQYNNWTSRFIIACIVEAFHYLHSLGIIYRDLKPENIVINSIGYIKL 470
Query: 199 TDFGFCKLIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
DFG K I +T T GT EYLAPEII SK Y +VD+W+LG+L +E+ PF A
Sbjct: 471 IDFGSTKKIGSYKTKTFIGTLEYLAPEIIQSKHYNRAVDYWALGILTYEILENKTPFQAI 530
Query: 258 DPMRIYEKIVAG---KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFR 314
+ + I I+ G Y P S KD I +LQ + R G L++GV D +NHKWF
Sbjct: 531 NDLEICNNILRGFNDNYFSPFIKSAG-KDFIKSLLQNNPLNRLGCLQNGVADIRNHKWFN 589
Query: 315 EIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF--DEEKI 351
+W + N ++ P P I++ D NFD + D E++
Sbjct: 590 SFNWRDLQNQKMSSPIVPTIKNHLDRRNFDKYPPDHEEV 628
>UniRef50_P24583 Cluster: Protein kinase C-like 1; n=5;
Ascomycota|Rep: Protein kinase C-like 1 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 1151
Score = 206 bits (502), Expect = 9e-52
Identities = 110/295 (37%), Positives = 166/295 (56%), Gaps = 7/295 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC--- 112
L++F KVLG G FG V L K T + A+K+L+K+ I++ IE + EKK+
Sbjct: 821 LDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLAT 880
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+ + F+ +Y+ + FI GG++ H++ + AKFY A+V+LAL+Y
Sbjct: 881 KTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLSVRRAKFYAAEVLLALKY 939
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSK 229
H ++YRDLK ENIL+ G+IKI D+G CK RT T CGTPE++APEI+ +
Sbjct: 940 FHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQ 999
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW+ GVLL++M PF D ++ I+ + P + E+ I +L
Sbjct: 1000 EYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLL 1059
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
D +R G + +FR I++D ILN R+ PP+ P+I+SP DT+ F+
Sbjct: 1060 TKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFE 1114
>UniRef50_A2DV83 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 740
Score = 205 bits (501), Expect = 1e-51
Identities = 112/299 (37%), Positives = 172/299 (57%), Gaps = 15/299 (5%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF + + +GAF VFL TG YA+K+ K + + + EK IL + P
Sbjct: 321 DFTFIRKISSGAFAKVFLAIKTRTGDIYAIKVTPKSSLKQKNTFKRVLTEKDILLQNSNP 380
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F+V Y + LY V+ ++ GG+++S L +G +ET+A+ Y AQ++ ALEYLH+
Sbjct: 381 FIVDFYYSIIGDHNLYLVMEYLPGGDLYSLLNNIGSLDETAARIYTAQIVKALEYLHSHG 440
Query: 178 LVYRDLKPENILIDRTGYIKITDFG------FCKLIRGRTWTLCGTPEYLAPEIILSKGY 231
+V+RDLKP+NILI+ +G +K+TDFG + + I + T+ GTP+YLAPEIILS +
Sbjct: 441 IVHRDLKPDNILINISGKLKLTDFGLSLYGAYDRAIPDDSKTIVGTPDYLAPEIILSSKH 500
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP--SHFSVELKDIIGHVL 289
+ D+WSLG +++E G PPF M + +I+ G++ S E+ D+I H+L
Sbjct: 501 SFTADYWSLGCVIYEFLTGAPPFHMETEMETFAQILTGRFDIDPLEDMSDEVIDLIKHLL 560
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDE 348
QVD +R G +G+ + +H WF +DWD+I + P F P+ P D + D F E
Sbjct: 561 QVDPEKRLGF--NGIKEIMDHPWFAGLDWDAI--DDLEPVFVPE---PKDKYSVDYFTE 612
>UniRef50_Q59EH6 Cluster: 3-phosphoinositide dependent protein
kinase-1 variant; n=9; Euteleostomi|Rep:
3-phosphoinositide dependent protein kinase-1 variant -
Homo sapiens (Human)
Length = 492
Score = 205 bits (501), Expect = 1e-51
Identities = 95/270 (35%), Positives = 168/270 (62%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 119 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 178
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ ALEYLH
Sbjct: 179 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 238
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ +I+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 239 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 298
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 299 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 358
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 359 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 388
>UniRef50_O15530 Cluster: 3-phosphoinositide-dependent protein
kinase 1; n=31; Deuterostomia|Rep:
3-phosphoinositide-dependent protein kinase 1 - Homo
sapiens (Human)
Length = 556
Score = 205 bits (501), Expect = 1e-51
Identities = 95/270 (35%), Positives = 168/270 (62%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ ALEYLH
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 200
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ +I+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 260
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 320
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 321 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 350
>UniRef50_Q22LX8 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 679
Score = 205 bits (500), Expect = 2e-51
Identities = 100/286 (34%), Positives = 173/286 (60%), Gaps = 5/286 (1%)
Query: 47 DDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYY 106
+ S+++ NDF + LG GAFG VFLV+ ++AMK+L+KE+I+ ++++
Sbjct: 340 ESSSKNSVGPNDFTIVETLGKGAFGQVFLVQKKDDKLFFAMKVLQKERILGKNILKYALT 399
Query: 107 EKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166
E+ +L + PF+V +KY F+ LY V+ + GG++ + L + G+ E AK Y ++
Sbjct: 400 ERNVLSVMQHPFIVSLKYAFQTKNKLYLVMDYCPGGDLDNLLFRKGRIPEPIAKIYICEI 459
Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAP 223
ILALE LH +V+RDLKP N+++D+ G+ ITDFG K + RG T + CG+ YL P
Sbjct: 460 ILALEALHNSNIVFRDLKPSNVVLDKDGHACITDFGLAKQGMQRGDITKSFCGSLAYLPP 519
Query: 224 EIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKD 283
E++ G+ S+DW+ LGVL++E+ G PP+++ + ++++ I + P S K
Sbjct: 520 EMLNKTGHTQSLDWYLLGVLMYELLEGMPPYYSDNKQKLFDNIRNAPLKMPKQASDAAKS 579
Query: 284 IIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
++ +L D +R G+ G + K+H +FR+++W+ + N ++ PP
Sbjct: 580 LLKGLLSKDPIQRLGS--KGAEEVKSHPFFRDVNWEDVYNKKLLPP 623
>UniRef50_UPI00006A08A1 Cluster: Serine/threonine-protein kinase
MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase
gamma) (Myotonic dystrophy kinase-related CDC42-binding
kinase gamma) (Myotonic dystrophy protein kinase-like
alpha) (MRCK gamma) (DMPK-like gamma).; n=1; Xenopus
tropicalis|Rep: Serine/threonine-protein kinase MRCK
gamma (EC 2.7.11.1) (CDC42- binding protein kinase
gamma) (Myotonic dystrophy kinase-related CDC42-binding
kinase gamma) (Myotonic dystrophy protein kinase-like
alpha) (MRCK gamma) (DMPK-like gamma). - Xenopus
tropicalis
Length = 1564
Score = 204 bits (499), Expect = 2e-51
Identities = 117/314 (37%), Positives = 188/314 (59%), Gaps = 21/314 (6%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
K +DFE KV+G GAFG V +VK +GK +AMK+L K ++++ + E+ +L
Sbjct: 73 KRDDFEIVKVIGRGAFGEVAVVKMKGSGKIFAMKILHKWEMLKRAETACFREERDVLVKG 132
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYL 173
+ ++ + Y F D+ YLY V+ + GG++ + L K + E A+FY A+++LA++ +
Sbjct: 133 DTQWIPSLHYAFHDDNYLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVLAIDSI 192
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEIILS- 228
H V+RD+KP+N+LID G+I++ DFG C ++ + GTP+Y++PEI+ +
Sbjct: 193 HQLNYVHRDIKPDNVLIDLKGHIRLADFGSCLKMKPDGTVESSVAVGTPDYISPEILQAM 252
Query: 229 ---KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSHF---SV 279
KG YG+ DWWSLGV ++E+ G PF+A + Y KI+ + + PS S
Sbjct: 253 EDGKGKYGIECDWWSLGVSMYELLFGETPFYAESLVETYGKIMNHEEHLQFPSDITDVSE 312
Query: 280 ELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGD 339
+ KD+I ++ R G K G+ DFK H +F +DWD+I N+ PP+ P++ SP D
Sbjct: 313 KAKDLIQRLI-CRKEERLG--KGGIDDFKKHPFFNGVDWDNIRNA--IPPYTPEVDSPAD 367
Query: 340 TTNFDVFDEEKIKD 353
T+NFDV D+E +K+
Sbjct: 368 TSNFDV-DDESLKN 380
>UniRef50_P34100 Cluster: Developmentally-regulated protein kinase
1; n=3; Dictyostelium discoideum|Rep:
Developmentally-regulated protein kinase 1 -
Dictyostelium discoideum (Slime mold)
Length = 416
Score = 204 bits (498), Expect = 3e-51
Identities = 105/267 (39%), Positives = 156/267 (58%), Gaps = 5/267 (1%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
K++DF LG+G+FG L +H +G ++ K L +E IV K EH E I+ +
Sbjct: 32 KISDFNFYGSLGSGSFGTAKLCRHRGSGLFFCSKTLRRETIVHEKHKEHVNNEINIMLNI 91
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ P++V F +++++ + ++F HLR F E + K A+++LA+EYLH
Sbjct: 92 SHPYIVKTYSTFNTPTKIHFIMEYAGKKDLFHHLRANKCFTEQTTKLIVAEIVLAIEYLH 151
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG--RTWTLCGTPEYLAPEII-LSKGY 231
A ++YRDLKPENILID G+IK+TDFGF K G T ++CGT +Y+APEI+ S G+
Sbjct: 152 AENIIYRDLKPENILIDEKGHIKLTDFGFSKKTVGGKNTSSVCGTFDYMAPEILNSSNGH 211
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G VDWW+LGV+++E+ G PF S + K S+ S E+KD I +L V
Sbjct: 212 GKPVDWWALGVVVYELVTGKLPFSNSKESLLNRKADFQLIFQNSYLSDEIKDFIFQLLSV 271
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDW 318
D ++R GT +NHKWF +I+W
Sbjct: 272 DPSKRLGTFDS--CSIRNHKWFSDINW 296
>UniRef50_Q23NJ5 Cluster: Protein kinase domain containing protein;
n=1; Tetrahymena thermophila SB210|Rep: Protein kinase
domain containing protein - Tetrahymena thermophila
SB210
Length = 1598
Score = 204 bits (497), Expect = 4e-51
Identities = 117/314 (37%), Positives = 179/314 (57%), Gaps = 16/314 (5%)
Query: 45 SWDDKSES--NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIE 102
S DKS+ L DF K +G G F V+LV+ GK YA+K++EK+ I+ K+ +
Sbjct: 561 SQTDKSQQPYQVSLKDFHFIKCVGMGGFSRVYLVQKKDNGKMYALKLIEKKFILTNKKEQ 620
Query: 103 HSYYEKKILCGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKF 161
E+ I+ + PF++ + Y F+ Y+ + + + AGGEMF HLRK+ K E A+F
Sbjct: 621 IVQNERNIMTMMQGHPFLLQLDYAFESKNYIAFAMEYCAGGEMFYHLRKIKKMTEEQARF 680
Query: 162 YGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR---TWTLCGTP 218
Y ++ L ++YLH ++YRD+KPENIL+D G+I+I DFG K ++ CG+P
Sbjct: 681 YFIEICLGIDYLHDRHIIYRDIKPENILLDIDGHIRIGDFGLSKPDMDDNEFAYSFCGSP 740
Query: 219 EYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH-- 276
EY+APE++L G+ VD ++LG LL+E+ G PPF++ IY+ I++ P H
Sbjct: 741 EYMAPEMLLKVGHAYPVDHYTLGALLYELVTGLPPFYSQITEEIYKSILSEDLTFPDHVN 800
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
S ELK+++ +L +R G G + +H W R+I+ I+ RI PP KI
Sbjct: 801 LSSELKNLLRGLLTKHPLQRLGQ-NMGTKEILSHPWCRKINLADIIYKRIEPPV--KI-- 855
Query: 337 PGDTTNFDVFDEEK 350
D F+ FDEE+
Sbjct: 856 --DVMGFN-FDEEE 866
>UniRef50_A0EEZ4 Cluster: Chromosome undetermined scaffold_92, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_92,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 319
Score = 204 bits (497), Expect = 4e-51
Identities = 109/299 (36%), Positives = 168/299 (56%), Gaps = 5/299 (1%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E+ KL D+ + L F I L K+ TG Y +K+ K+ + + + +++I
Sbjct: 8 EAKQKLKDYRILQTLCQIDFSIYKLAKNKKTGDYILIKIYAKKSLTSNISLRNKVQQEQI 67
Query: 111 -LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
L L PF++ F+D Y + + GG + S L + + + A FY AQV+L
Sbjct: 68 FLSTLKSPFIIKTFDTFEDEDNYYILQEYCQGGNLISLLSRF-RPDNDLAVFYAAQVVLL 126
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIIL 227
LEYLH+ +++R + E I GY+KI+DF K + +GRT+T+ G EY+APE+I
Sbjct: 127 LEYLHSKNILFRCINSEIFHICSDGYLKISDFFHAKQMQKKGRTYTIAGFLEYIAPEVIC 186
Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGH 287
G+ +S DWW+LGVL+FE+ AG PF+ D ++ +I G+ + P +FS E KD+I
Sbjct: 187 QHGHALSPDWWALGVLIFELLAGILPFYG-DFHILFNQIQKGQIKYPDYFSKEAKDLISQ 245
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+LQV R G +K GV D K HKWF+ I+W + I P+ PKI GDT+N++ +
Sbjct: 246 LLQVRPFNRLGYIKGGVNDVKKHKWFKNINWKELAQKNIKAPYIPKINGFGDTSNYNYY 304
>UniRef50_UPI00006CB12C Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 1318
Score = 203 bits (496), Expect = 5e-51
Identities = 96/276 (34%), Positives = 167/276 (60%), Gaps = 4/276 (1%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF ++G G+FG V+LV+ + YAMK+L K KI+R +++ E+ ++ N P
Sbjct: 1006 DFIVHGLIGKGSFGEVYLVEKKGSQMLYAMKVLHKSKIIRHNLTKYAMTERNVMSLTNHP 1065
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F+V + Y F+ + L+ ++ + GG++ HL+K KF E K Y A+ ILALE LH +
Sbjct: 1066 FIVKLNYAFQTSDKLFLIMDYCPGGDLGEHLQKEKKFSEELVKIYLAETILALEDLHKRD 1125
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKL----IRGRTWTLCGTPEYLAPEIILSKGYGM 233
+++RDLKP+NI++D G++K+TDFG K + CG+ YLAPE++ G+G
Sbjct: 1126 VIFRDLKPDNIVLDYEGHVKLTDFGLSKEGVLDHSSGARSFCGSVAYLAPEMLKRCGHGK 1185
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
+VDW+ LGV+++E+ G PP++A++ ++ I + PS+ S E + ++ +LQ +
Sbjct: 1186 AVDWYLLGVVMYELLVGIPPYYANNRDELFYNIEKAPLKIPSYLSNEARSLLKALLQRNP 1245
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329
+R G+ K + K H +F ++DW+++ ++ PP
Sbjct: 1246 AKRLGSGKGDAEEIKAHPFFGDVDWNTVYQRKLKPP 1281
>UniRef50_A2E5K8 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 450
Score = 203 bits (496), Expect = 5e-51
Identities = 100/279 (35%), Positives = 161/279 (57%), Gaps = 7/279 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
++DF +V+G G +G V LV T + +A+K + K ++++ K+ + E+ IL +
Sbjct: 106 IDDFTPIRVIGNGYYGKVMLVTKKDTDEKFAIKSIHKSRLIQDKRSHSALAERNILLRAS 165
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V +K+ F+ Y+ L + +GGE+F+ ++K G E +FY ++++LAL YLH+
Sbjct: 166 HPFIVQLKFAFQTPSKFYFGLEYASGGELFARVQKSGGLSEKEVRFYLSEIVLALSYLHS 225
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRT--WTLCGTPEYLAPEIILSKGYGM 233
++YRDLKPENIL+D G++K+TDFG K + + T CGT EY+APEI + Y
Sbjct: 226 LGIIYRDLKPENILLDEEGHVKLTDFGLSKDLNATSGAQTFCGTYEYIAPEIAQHQPYSY 285
Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDT 293
VDWW++G+L +EM PFF RI EKIV P EL +I +L+ D
Sbjct: 286 EVDWWAIGILAYEMVMQVTPFFDKSQSRILEKIVNEDVSFPVEIPSELASLIAMLLRKDP 345
Query: 294 TRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
+R +D + +H +F ++WD + +I P + P
Sbjct: 346 KKR-AKYEDVI----HHPFFSGVNWDDVYQRKIKPYYIP 379
>UniRef50_A0C5F6 Cluster: Chromosome undetermined scaffold_15, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_15,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 629
Score = 203 bits (496), Expect = 5e-51
Identities = 99/276 (35%), Positives = 166/276 (60%), Gaps = 3/276 (1%)
Query: 63 KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYM 122
K+LG G+FG V+ G+ +A+K L KE++ ++ EK +L + PF+V +
Sbjct: 326 KLLGKGSFGEVYYATRKSDGEGFAIKTLCKERVFSKNLTRYAQTEKNVLSVMRHPFIVRL 385
Query: 123 KYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRD 182
F+++ L+ VL F GG++ L K K E A+FY ++ILALE LH +++RD
Sbjct: 386 HAAFQNSQKLFMVLDFCPGGDLGQLLTKQVKLSEEIARFYICEIILALESLHKNCIIFRD 445
Query: 183 LKPENILIDRTGYIKITDFGFCK--LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSL 240
LKP+N+++D G+ ++TDFG K + T + CG+ YL+PE+++ KG+ +VDW+ +
Sbjct: 446 LKPDNVVLDSKGHARLTDFGLSKEGIYDNITKSFCGSIAYLSPEVLMKKGHSRTVDWYLV 505
Query: 241 GVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTL 300
GVLL+EM G PP++ + +++E I G + P H S + +++I +L D +R G+
Sbjct: 506 GVLLYEMIVGLPPYYHQNREQLFENIKKGVLKIPKHMSQDARELIKGLLIRDPAQRLGS- 564
Query: 301 KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
K+ D K H +F++++WD+I+N PF K RS
Sbjct: 565 KNDAEDLKKHAFFKDVNWDNIMNKVEDGPFIEKNRS 600
>UniRef50_UPI000069DCCB Cluster: UPI000069DCCB related cluster;
n=10; Xenopus tropicalis|Rep: UPI000069DCCB UniRef100
entry - Xenopus tropicalis
Length = 338
Score = 203 bits (495), Expect = 7e-51
Identities = 113/296 (38%), Positives = 167/296 (56%), Gaps = 10/296 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL---C 112
L +F KVLG G FG VFL ++ T + A+K L+KE+I+ I+ + EK+IL
Sbjct: 6 LENFNLGKVLGEGTFGKVFLAEYKDTKQLCAIKTLKKERIIAKNDIKSVFKEKRILQKVT 65
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ +L++V+ ++ GG++ L G FEE+ A FY A ++L LE
Sbjct: 66 SAEHPFLVSLYATFQSENHLFFVMEYLPGGDLCHLLEHQGAFEESKAMFYTACIVLGLEE 125
Query: 173 LHACELV--YRDLKPENILIDRTGYIKITDFGFCKLIRG-----RTWTLCGTPEYLAPEI 225
LH +V +RDLK EN+++D GY+KI DFG K G R+ TLCGT Y+APEI
Sbjct: 126 LHRNNIVHRFRDLKLENLMVDVHGYLKIVDFGLSKDGNGFRYGDRSKTLCGTNCYMAPEI 185
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
I Y +VDWW+LGV+L+ M PF A D M ++E I K S E + +I
Sbjct: 186 IDEMAYSRAVDWWALGVVLYVMIMFQFPFDAEDDMELFESIRNDKPALTEELSEEAQCLI 245
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
+L+ + RR G + G + K H++F +IDW+ L + PPF P + ++T
Sbjct: 246 LRLLEKNPCRRLGYSEAGAEEVKAHEFFEDIDWEEFLERELMPPFKPDVSGLTEST 301
>UniRef50_Q5QFC4 Cluster: EnvDll2-01; n=1; Oikopleura dioica|Rep:
EnvDll2-01 - Oikopleura dioica (Tunicate)
Length = 703
Score = 203 bits (495), Expect = 7e-51
Identities = 112/305 (36%), Positives = 168/305 (55%), Gaps = 29/305 (9%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHI-VTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+ D + K LG G FG+V LVK + K +A+K ++K ++V Q H EK IL +
Sbjct: 413 VKDLDIVKPLGAGGFGVVKLVKVSGIKNKAFALKYIQKARVVEYGQESHVVDEKNILGLM 472
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF++ + FK G F+++ A+FY VI A +Y+H
Sbjct: 473 KSPFILGLLRTFK------------------------GPFKDSVARFYAGCVINAFDYMH 508
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK-LIRG-RTWTLCGTPEYLAPEIILSKGYG 232
+ + YRDLKPEN+++D GY+++ D GF K ++ G +TWT CGTPEY++PEII + G+
Sbjct: 509 SRDYCYRDLKPENLMVDEKGYVRLVDLGFAKKVLPGHKTWTFCGTPEYISPEIITNSGHN 568
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK--DIIGHVLQ 290
+S D W LG+L+FE+ PFFA + M IYEKI+ G + F V K +I + +
Sbjct: 569 VSADLWCLGILIFELLCRKTPFFAKNDMDIYEKILQGIHAVSIPFRVSRKAESLIKQLCK 628
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEK 350
D + R G KDG D + H+W+ DW+++ N ++ P P I S D +NF F E
Sbjct: 629 RDPSERIGYQKDGFEDIRRHRWYAGFDWEALENEKMIAPHVPYISSFEDCSNFTPFKPED 688
Query: 351 IKDSP 355
K+ P
Sbjct: 689 EKNIP 693
>UniRef50_A2FNQ5 Cluster: AGC family protein kinase; n=1;
Trichomonas vaginalis G3|Rep: AGC family protein kinase
- Trichomonas vaginalis G3
Length = 696
Score = 203 bits (495), Expect = 7e-51
Identities = 107/282 (37%), Positives = 167/282 (59%), Gaps = 9/282 (3%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF K + +GA+ V+L + T YA+K+ K ++ + ++ EK IL + P
Sbjct: 303 DFTFIKRISSGAYAKVYLAEKNSTKDTYAIKVTPKSELRQKNEVRRVLTEKDILLKNSNP 362
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
++V + Y LY V+ F+ GG+++S L+ +G +E S++ Y AQ++ AL++LH
Sbjct: 363 YIVEIYYSIIGKHNLYLVMDFVPGGDLYSLLQNIGTLDEDSSRIYIAQIVQALDFLHGKG 422
Query: 178 LVYRDLKPENILIDRTGYIKITDFG---FCKLIRGRTWTLCGTPEYLAPEIILSKGYGMS 234
+++RDLKP+NILI G +K+TDFG + RG + L GTP Y+APEIILS+ +
Sbjct: 423 ILHRDLKPDNILISCEGKLKLTDFGLSLYGAFDRGNSEGLVGTPGYMAPEIILSQPHNQC 482
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSHFSVELKDIIGHVLQVD 292
VD+WSLGV+LFE+ G PPF + ++ IV+GK + S + D I +L VD
Sbjct: 483 VDYWSLGVILFELLTGIPPFNRATEQETFQAIVSGKCDWSLLEDVSNDGIDFIRKLLTVD 542
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI 334
++R G +G+ D KNH WF+ I+WD + + PPF PK+
Sbjct: 543 PSKRLGA--NGISDIKNHSWFKSINWDKV--EELPPPFVPKV 580
>UniRef50_A0E1G0 Cluster: Chromosome undetermined scaffold_73, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_73,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 371
Score = 203 bits (495), Expect = 7e-51
Identities = 111/317 (35%), Positives = 176/317 (55%), Gaps = 12/317 (3%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDKSESN-AKLNDFERQKVLGTGAFGIVFLVKHI-V 80
+ +++ +KK+ + + K+E L DF Q +G G FG V VK
Sbjct: 5 FQQEEEKNQKSSIKKVDSFLAKQIEKKNEKQKVTLKDFLSQGEIGRGKFGKVLRVKMKGK 64
Query: 81 TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIA 140
+ YAMK+++K I++ +EH+ EK +L PFVV +KY F+ LY V+ FI
Sbjct: 65 DNREYAMKVIKKADILQYGLVEHTMLEKNVLGASRNPFVVKLKYSFQTEQKLYLVMEFIK 124
Query: 141 GGEMFSHLRKM--GKFEETSAKFYGAQVILALEYLH-ACELVYRDLKPENILIDRTGYIK 197
GG++ LRK G+F E +F A++IL L+Y+H ++YRDLKPEN+++ G++K
Sbjct: 125 GGQLAKVLRKRQSGRFTEEQTRFCAAEIILGLQYMHNTLRVIYRDLKPENVMVTEEGHLK 184
Query: 198 ITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF 254
+TDFG K + +TL GTPEYLAPEI++++G+ VD+W LGVL++EM G PF
Sbjct: 185 LTDFGLSKQYETEEAKFFTLAGTPEYLAPEILVNQGHNHMVDFWCLGVLIYEMLVGETPF 244
Query: 255 F--ASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKW 312
+ + I I + + P+ S + K I+ +L D +R G + + K+H +
Sbjct: 245 YDCQRNHNTIEHNIKNAQIKYPNFLSEQSKSIVDRLLNKDPKQRLGA--KSIQEIKDHHF 302
Query: 313 FREIDWDSILNSRIHPP 329
F +I+W+ + N I P
Sbjct: 303 FDDINWEQLYNLEIPSP 319
>UniRef50_Q8SRK8 Cluster: Probable cAMP-dependent protein kinase
catalytic subunit; n=2; Encephalitozoon|Rep: Probable
cAMP-dependent protein kinase catalytic subunit -
Encephalitozoon cuniculi
Length = 322
Score = 203 bits (495), Expect = 7e-51
Identities = 109/282 (38%), Positives = 163/282 (57%), Gaps = 8/282 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLK---QIEHSYYEKKI 110
K+ DFE KV+G GAFG V LV+ +AMKML+ +I+R + Q+E+ K
Sbjct: 3 KIQDFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKR 62
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G F +Y + V L ++ ++ GGE+F L+K G+F+E A+FY A++I AL
Sbjct: 63 IYGCPFVAKLYSTDFHGGKVGL--IMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISAL 120
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKG 230
++H ++YRDLKPENILI TG+IK+ DFGF + + GTPEY++PE + S+
Sbjct: 121 RFIHGRGILYRDLKPENILITSTGHIKLIDFGFSVYESENIYMISGTPEYMSPEKLRSED 180
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
G + D+W LGV+++EM G PPF+ S IY KI+ P + S + +I +L
Sbjct: 181 DGRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHYVSPVARCLITGLLD 240
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
+ R GT G+ + H +F+ IDW + + RI PPF P
Sbjct: 241 KNRATRLGT--KGICEIMGHPFFKGIDWHEVESRRIEPPFIP 280
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.323 0.142 0.442
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 450,727,097
Number of Sequences: 1657284
Number of extensions: 20069630
Number of successful extensions: 71637
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 8002
Number of HSP's successfully gapped in prelim test: 3171
Number of HSP's that attempted gapping in prelim test: 46889
Number of HSP's gapped (non-prelim): 14587
length of query: 366
length of database: 575,637,011
effective HSP length: 102
effective length of query: 264
effective length of database: 406,594,043
effective search space: 107340827352
effective search space used: 107340827352
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 73 (33.5 bits)
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