BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001163-TA|BGIBMGA001163-PA|IPR002290|Serine/threonine protein kinase, IPR000961|Protein kinase, C-terminal, IPR000719|Protein kinase, IPR008271|Serine/threonine protein kinase, active site, IPR011009|Protein kinase-like (366 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 323 2e-89 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 268 8e-73 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 246 4e-66 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 243 3e-65 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 233 4e-62 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 219 4e-58 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 212 6e-56 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 162 6e-41 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 156 4e-39 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 156 4e-39 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 140 2e-34 SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 136 5e-33 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 134 2e-32 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 132 6e-32 SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 130 3e-31 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 130 4e-31 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 129 7e-31 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 123 5e-29 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 123 5e-29 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 122 8e-29 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 121 1e-28 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 121 2e-28 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 120 2e-28 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 117 2e-27 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 116 5e-27 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 115 9e-27 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 114 2e-26 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 114 2e-26 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 112 6e-26 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 111 1e-25 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 110 3e-25 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 107 3e-24 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 107 3e-24 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 107 3e-24 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 102 7e-23 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 102 9e-23 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 98 1e-21 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 97 3e-21 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 97 5e-21 SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Sch... 96 6e-21 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 95 2e-20 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 94 3e-20 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 93 6e-20 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 92 1e-19 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 88 2e-18 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 87 3e-18 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 87 3e-18 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 87 5e-18 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 84 3e-17 SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schiz... 81 2e-16 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 80 4e-16 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 80 6e-16 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 79 1e-15 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 79 1e-15 SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizo... 78 2e-15 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 78 2e-15 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 77 3e-15 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 75 1e-14 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 75 2e-14 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 74 3e-14 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 73 9e-14 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 72 1e-13 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 72 1e-13 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 71 2e-13 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 71 2e-13 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 71 3e-13 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 71 3e-13 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 70 6e-13 SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizo... 69 8e-13 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 66 1e-11 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 64 2e-11 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 64 2e-11 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 64 3e-11 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 63 5e-11 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 63 5e-11 SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizo... 63 7e-11 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 62 9e-11 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 60 5e-10 SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosa... 59 1e-09 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 57 3e-09 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 57 3e-09 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 57 5e-09 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 56 6e-09 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 54 2e-08 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 54 2e-08 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 53 7e-08 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 51 3e-07 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 51 3e-07 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 48 2e-06 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 48 2e-06 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 46 6e-06 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 43 6e-05 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 42 1e-04 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 42 1e-04 SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosacchar... 39 0.001 SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizo... 38 0.002 SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schiz... 38 0.003 SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schi... 37 0.005 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 36 0.009 SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces p... 34 0.028 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 33 0.064 SPBC336.14c |ppk26||serine/threonine protein kinase Ppk26|Schizo... 33 0.084 SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizos... 31 0.26 SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosa... 30 0.59 SPAC1F7.05 |cdc22||ribonucleoside reductase large subunit Cdc22|... 29 1.0 SPAC4D7.01c |sec71|sec7a, SPAP8A3.15c|Sec7 domain|Schizosaccharo... 28 1.8 SPBC577.06c |||phosphatidylinositol kinase |Schizosaccharomyces ... 28 2.4 SPCC1322.12c |bub1||serine/threonine protein kinase Bub1|Schizos... 27 4.2 SPAC31A2.05c |mis4||cohesin loading factor Mis4|Schizosaccharomy... 27 4.2 SPBC359.05 |abc3||ABC transporter Abc3|Schizosaccharomyces pombe... 27 5.5 SPBC215.11c |||aldo/keto reductase, unknown biological role|Schi... 27 5.5 SPBC6B1.10 |prp17||splicing factor Prp17|Schizosaccharomyces pom... 26 9.7 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 323 bits (794), Expect = 2e-89 Identities = 163/356 (45%), Positives = 227/356 (63%), Gaps = 11/356 (3%) Query: 2 ADSEIKRHINSPRGDL-IQHGGYSPAKQEQYSQYLKKLR--------QDFVESWDDKSES 52 + S +RH RG+L +HG A ++++K+R + + D ++ Sbjct: 135 SQSSHQRHSRDGRGELGSEHGERRSAMDGLRDRHIRKVRVSQLLDLQRRRIRPADHTTKD 194 Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112 + DF + LGTG+FG V LV+ YYA+K+LEK+KIV +KQIEH+ E+ IL Sbjct: 195 RYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILS 254 Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172 + PF+ + F+D L+ V+ F GGE+FS LRK +F E AKFY A+VILAL+Y Sbjct: 255 RVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDY 314 Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR-GRTWTLCGTPEYLAPEIILSKGY 231 LH ++VYRDLKPEN+L+DR G++KI DFGF K + TLCGTP+YLAPEII K Y Sbjct: 315 LHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCCTLCGTPDYLAPEIISLKPY 374 Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291 + DWWSLG+L+FEM AG+PPF++ +PM++YE I+ GK PS+FS D++ H+LQ Sbjct: 375 NKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLLQR 434 Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS-PGDTTNFDVF 346 D T RYG LKDG +D H WFR+I WD IL +I P+ P I++ GD++ FD + Sbjct: 435 DITCRYGNLKDGSMDIIMHPWFRDISWDKILTRKIEVPYVPPIQAGMGDSSQFDAY 490 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 268 bits (657), Expect = 8e-73 Identities = 134/305 (43%), Positives = 190/305 (62%), Gaps = 6/305 (1%) Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115 ++ FE KV+G G+FG V V+ T + YA+K ++K IV +++H+ E+ +L +N Sbjct: 227 IDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVN 286 Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175 PF+V +K+ F+ LY VL F+ GGE+F HL++ G F+ AKFY A++++ALE LH Sbjct: 287 NPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHE 346 Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGYG 232 ++YRDLKPENIL+D TG+I + DFG CKL RT T CGTPEYLAPE++L GY Sbjct: 347 FNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGYT 406 Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292 VDWW+LGVLL+EM G PPF+ + +Y KI+ R P + + KD++ +L Sbjct: 407 KVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTRA 466 Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351 +R G+ G + KNH +F +IDW + +I PPF P + S DT+NFD F E Sbjct: 467 PEKRLGS--GGAQEIKNHPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFTSEIP 524 Query: 352 KDSPV 356 DS V Sbjct: 525 MDSVV 529 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 246 bits (602), Expect = 4e-66 Identities = 124/295 (42%), Positives = 181/295 (61%), Gaps = 9/295 (3%) Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF- 116 DF +++G G FG V+LV+ T + YAMK + K+ IVR K++ H+ E+ IL + Sbjct: 301 DFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSLD 360 Query: 117 --PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174 PF+V +K+ F+ LY + +++GGE+F HL+ G+F E AKFY A+++LALE+LH Sbjct: 361 ESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLH 420 Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEIIL-SKG 230 +++YRDLKPENIL+D G+I + DFG K T T CGT EYLAPE++L KG Sbjct: 421 KHDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGTTEYLAPEVLLEDKG 480 Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH-FSVELKDIIGHVL 289 Y VD+WSLGVL+FEM G PF+A D ++Y I GK R P S E + + +L Sbjct: 481 YTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGVLSSEGRSFVRGLL 540 Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344 + R G + D + K H +F +I+WD + ++ PPF P +++ D +NFD Sbjct: 541 NRNPNHRLGAVAD-TTELKEHPFFADINWDLLSKKKVQPPFKPNVQNDLDVSNFD 594 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 243 bits (595), Expect = 3e-65 Identities = 132/297 (44%), Positives = 184/297 (61%), Gaps = 9/297 (3%) Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC---G 113 +DF K++G G FG V+LV+ T + YAMK+L K+ IVR K++ H+ E+ IL Sbjct: 264 DDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQTSA 323 Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173 + PF+V +++ F+ LY V ++AGGE+F HL+K +F E AKFY A+++LAL+ L Sbjct: 324 ADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQAL 383 Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWTLCGTPEYLAPEIILSK- 229 H +VYRDLKPENIL+D G+I + DFG K + T T CGT +YLAPE+IL + Sbjct: 384 HKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVGTTTRTFCGTTDYLAPEVILDEA 443 Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP-SHFSVELKDIIGHV 288 GY M VD+WSLGVLL+EM+ G PF+A + ++Y+ IV GK R P SVE +D+I + Sbjct: 444 GYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLLSVEARDLIKLL 503 Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345 L + R G D V + H +F IDW + I PPF P + D +NFDV Sbjct: 504 LNRNPKHRLGAHGD-VEEVMKHPFFDGIDWKKLAAKEISPPFKPIVEGEIDVSNFDV 559 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 233 bits (569), Expect = 4e-62 Identities = 128/329 (38%), Positives = 188/329 (57%), Gaps = 9/329 (2%) Query: 41 DFVESWDDKSESNAKLN--DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIV-R 97 DF+ S D + K+ DF+ VLG G++G V LVK TG+ +A K L+K IV R Sbjct: 71 DFISSKGDNYVPSGKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLR 130 Query: 98 LKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEET 157 K +E + E++IL + PF+ + Y F+D+ LY +L + GGE+FSHL + E Sbjct: 131 AKGLEQTKNERQILEEVRHPFICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPED 190 Query: 158 SAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRT--WTLC 215 FY A++ LAL +LH +VYRDLKPEN L+D G+I +TDFG K+ + Sbjct: 191 VVAFYTAELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCRSFV 250 Query: 216 GTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPS 275 GT EY APEI+L + Y +VDWWS+G+L+F++ G PPF A++ RI EKI K P Sbjct: 251 GTEEYCAPEILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPF 310 Query: 276 HFSVELKDIIGHVLQVDTTRRYGT--LKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333 + + + +DII L+ + +R G + G K H+ +R IDW+ + + PP P Sbjct: 311 YVTSDARDIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPC 370 Query: 334 IRSPGDTTNFDV-FDEEKIKDSPVCLYEE 361 I +P NF V F + + +P+ L+EE Sbjct: 371 ITNPEAAENFSVEFTKLPLSTTPI-LHEE 398 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 219 bits (536), Expect = 4e-58 Identities = 113/307 (36%), Positives = 175/307 (57%), Gaps = 10/307 (3%) Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115 L DF VLG G FG V L + + YA+K+L+KE I+ ++E + EK++ N Sbjct: 680 LEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVAN 739 Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172 PF+V + F+ +Y+V+ F++GG++ H+++ +F A+FY A+V LAL+Y Sbjct: 740 RERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE-QFSRRRAQFYAAEVCLALKY 798 Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSK 229 H ++YRDLK +NIL+ G++K+ D+G CK T T CGTPE++APEI+L + Sbjct: 799 FHDNGIIYRDLKLDNILLSPDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAPEILLEQ 858 Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289 Y SVDWW+ GVL+++M G PF D I++ I++ + P H + I+ +L Sbjct: 859 QYTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYPIHMPRDSVSILQQLL 918 Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349 D +R G+ + D H +F I+WD I + R PP+ P + SP DT FDEE Sbjct: 919 TRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSLNSPTDT---KYFDEE 975 Query: 350 KIKDSPV 356 ++ PV Sbjct: 976 FTRELPV 982 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 212 bits (518), Expect = 6e-56 Identities = 110/315 (34%), Positives = 176/315 (55%), Gaps = 7/315 (2%) Query: 36 KKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI 95 K + ES + ++ L+DF VLG G FG V L ++ V K+YA+K+L+KE I Sbjct: 641 KDANRSVPESPRREKKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAI 700 Query: 96 VRLKQIEHSYYEKKILCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152 ++ +++E EK + N PF++ + F+ + +Y+V+ +I GG++ H+++ Sbjct: 701 LKNEELESLKTEKHVFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQ- 759 Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRG 209 +F A+FYGA+V LAL+Y H + YRDLK +NIL+ G+I+I D+G CK L+ Sbjct: 760 QFSVKRARFYGAEVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGN 819 Query: 210 RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG 269 T T CGTPE++APEI+L + Y VDWW+ GVL+++M G PF D I++ I++ Sbjct: 820 TTSTFCGTPEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSD 879 Query: 270 KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329 + P + + ++ +L D +R G+ + H +F I WD + N P Sbjct: 880 EPLFPINMPADAVSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPS 939 Query: 330 FFPKIRSPGDTTNFD 344 + P I P D NFD Sbjct: 940 YKPLINDPRDLNNFD 954 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 162 bits (394), Expect = 6e-41 Identities = 84/275 (30%), Positives = 155/275 (56%), Gaps = 16/275 (5%) Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN-F 116 D+ ++G G+F V + K YA+K+L+K+ IV+ ++++ E+ + LN F Sbjct: 53 DYVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGF 112 Query: 117 PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHAC 176 P + + + F+D++ LYYVL GE+ +++K +E +FY A+++ ++EY+H+C Sbjct: 113 PGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSC 172 Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR--------TW--TLCGTPEYLAPEII 226 +++RDLKPENIL D ++KITDFG K++ + T+ + GT EY+APE++ Sbjct: 173 GIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAEYVAPELL 232 Query: 227 LSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIG 286 + S D W+ ++++M G PPF S+P I++KI++ +Y P ++ + Sbjct: 233 SRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPKLLPPDIVPLFS 292 Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSI 321 H+ ++ + R T + K +F I WD++ Sbjct: 293 HLFRIQPSDRSTTQQ-----IKQFPFFATITWDNL 322 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 156 bits (379), Expect = 4e-39 Identities = 90/240 (37%), Positives = 130/240 (54%), Gaps = 2/240 (0%) Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118 FE K LG G FG V+L K TG A+K L K ++V+ K + E +I L Sbjct: 89 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 148 Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178 ++ + +F D +Y +L F GE++ HLR+ +F E A Y Q+ AL YLH + Sbjct: 149 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHV 208 Query: 179 VYRDLKPENILIDRTGYIKITDFGF-CKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDW 237 ++RD+KPENIL+ G IK++DFG+ R TLCGT +YL PE++ K + VD Sbjct: 209 IHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVDL 268 Query: 238 WSLGVLLFEMSAGHPPF-FASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR 296 WSLGVL +E G PPF S Y++I + PS + +D+I +LQ + +R Sbjct: 269 WSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISRLLQHNPEKR 328 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 156 bits (379), Expect = 4e-39 Identities = 94/305 (30%), Positives = 162/305 (53%), Gaps = 27/305 (8%) Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114 +++DF+ ++LG G++ V T + YA+K+L+K I++ K+ ++ EK+ LC L Sbjct: 95 RVSDFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCIL 154 Query: 115 N-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173 + P + + Y F+D LY+VL GE+ ++ K+G+F E A++Y A ++ +++Y+ Sbjct: 155 SKHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYM 214 Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLI-----------------RGRTWTLCG 216 H +++RDLKPENIL+D KITDFG K++ + + + G Sbjct: 215 HGRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVG 274 Query: 217 TPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH 276 T Y++PE++ K G + D W+ G +LF+M AG PPF A + ++ I+ Y P Sbjct: 275 TARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPD 334 Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336 S D+I +L +D R V + H +F I +D+ L PP P+++ Sbjct: 335 ISDVASDLIKKLLVLDPKDRL-----TVDEIHQHPFFNGIKFDNTLWEL--PP--PRLKP 385 Query: 337 PGDTT 341 G T+ Sbjct: 386 FGHTS 390 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 140 bits (340), Expect = 2e-34 Identities = 94/294 (31%), Positives = 146/294 (49%), Gaps = 16/294 (5%) Query: 53 NAKLNDF-ERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111 N K N F R +G G F F VK G YA K++ K + K + E K+ Sbjct: 34 NNKKNIFYTRYDCIGEGGFARCFRVKDNY-GNIYAAKVIAKRSLQNDKTKLKLFGEIKVH 92 Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171 ++ P +V F+D+ +Y +L + LRK + E ++ Q++ AL+ Sbjct: 93 QSMSHPNIVGFIDCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALK 152 Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILS 228 Y+H +++RDLK NI++D + +KI DFG L+ R T+CGTP Y+APEI+ + Sbjct: 153 YMHKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFN 212 Query: 229 --KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH--FSVELKDI 284 +G+ VD WS GV+++ + G PPF + IY KI A Y PS+ S E KD+ Sbjct: 213 SKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDL 272 Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRI-HP-PFFPKIRS 336 I +L D +++ + D +H++F S L I H P +P +S Sbjct: 273 ISSLLTHDP-----SIRPSIDDIVDHEFFHTGYMASTLPDEILHSMPIWPSSQS 321 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 136 bits (329), Expect = 5e-33 Identities = 89/265 (33%), Positives = 140/265 (52%), Gaps = 17/265 (6%) Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIV----RLKQIEHS 104 K+ ++ + +E + LG+G F +V L + +GK+YA+K++ K KI+ + E Sbjct: 157 KNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMF 216 Query: 105 YYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGA 164 E IL L+ P VV F+++ L+ V+ ++ GG++ L G +E K Sbjct: 217 QREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLK 276 Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGR-TW--TLCGTPEYL 221 Q++ L +LH + +RD+KPENILI ++KI+DFG K+I G T+ T CGT YL Sbjct: 277 QLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYL 336 Query: 222 APEIILSK------GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY---- 271 APE++ SK GY VD WSLG +L+ M PF +S + E I G Y Sbjct: 337 APEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEP 396 Query: 272 RCPSHFSVELKDIIGHVLQVDTTRR 296 + S E D+I +L+++ +R Sbjct: 397 LLENEISEEGIDLINRMLEINPEKR 421 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 134 bits (323), Expect = 2e-32 Identities = 91/290 (31%), Positives = 146/290 (50%), Gaps = 27/290 (9%) Query: 45 SWDDKSESNAK-LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK----------- 92 S D+K K + ++ K +G G+ G V + H+ TG+ +A+K++ + Sbjct: 110 SADEKPRERRKVIGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAA 169 Query: 93 --EKIVRLKQIE-----HSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMF 145 + + Q E + E + L P++ + + N + Y V F+ GG+M Sbjct: 170 ASAEATKAAQSEKNKEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQML 229 Query: 146 SHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK 205 ++ GK +E A+ + Q+ AL YLH +V+RDLK ENILI +TG IKI DFG Sbjct: 230 DYIISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSN 289 Query: 206 LIR--GRTWTLCGTPEYLAPEIILSKGY-GMSVDWWSLGVLLFEMSAGHPPFFASDPMRI 262 L R R T CG+ + APE++ ++ Y G VD WS G++L+ + G PF + + Sbjct: 290 LYRRQSRLRTFCGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSAL 349 Query: 263 YEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKW 312 + KI G PS+ S + K ++ +L D +R TL++ VL NH W Sbjct: 350 HAKIKKGTVEYPSYLSSDCKGLLSRMLVTDPLKR-ATLEE-VL---NHPW 394 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 132 bits (320), Expect = 6e-32 Identities = 63/147 (42%), Positives = 96/147 (65%) Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115 L DF KV+G GAFG V LV+ + TGK YAMK L K ++ + Q+ H E+ +L + Sbjct: 90 LEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVESD 149 Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175 P+VV + Y F+D++YLY ++ F+ GG++ + L F E +FY A+ +LA+ +H Sbjct: 150 SPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADVHR 209 Query: 176 CELVYRDLKPENILIDRTGYIKITDFG 202 ++RD+KP+NILIDR G+IK++DFG Sbjct: 210 MGYIHRDIKPDNILIDRDGHIKLSDFG 236 Score = 107 bits (258), Expect = 2e-24 Identities = 55/153 (35%), Positives = 83/153 (54%), Gaps = 9/153 (5%) Query: 208 RGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIV 267 R ++ GTP+Y+APEI L +GYG DWWSLG ++FE G PPF + + Y KI+ Sbjct: 286 RVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKII 345 Query: 268 AGK----YRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILN 323 + + H S+E +D++ L D+ R G + G ++ H +F IDWD I Sbjct: 346 NWRETLTFPNDIHLSIEARDLMDR-LMTDSEHRLG--RGGAIEIMQHPFFTGIDWDHIRE 402 Query: 324 SRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPV 356 + PF P ++S DT F V + E++ + PV Sbjct: 403 TA--APFIPNLKSITDTHYFPVDELEQVPEQPV 433 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 130 bits (314), Expect = 3e-31 Identities = 83/247 (33%), Positives = 125/247 (50%), Gaps = 15/247 (6%) Query: 63 KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF--PFVV 120 +VLG G + V HI T K YA K++ K K++ KQ + E IL +++ P ++ Sbjct: 35 RVLGGGTYATVREAVHIETNKMYAAKIMNK-KMMEKKQ-DFVKNEIAILKRVSYEHPNIL 92 Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVY 180 ++ +F+ LY + GGE+F + G F E A A++YLH +V+ Sbjct: 93 HLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDNGIVH 152 Query: 181 RDLKPENILI---DRTGYIKITDFGFCKLIRGRTW----TLCGTPEYLAPEIILSKGYGM 233 RDLKPEN+L D + I DFG + T CGTPEY+APE+ GYG Sbjct: 153 RDLKPENLLYRSKDPNSDLLIADFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRTGYGK 212 Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR----CPSHFSVELKDIIGHVL 289 VD W++GV+ + + +G+ PF + + E I+A +Y C S S KD I L Sbjct: 213 PVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAKDFIKKCL 272 Query: 290 QVDTTRR 296 + D ++R Sbjct: 273 ENDPSKR 279 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 130 bits (313), Expect = 4e-31 Identities = 89/269 (33%), Positives = 139/269 (51%), Gaps = 27/269 (10%) Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVY 121 Q++LG G F +++ TG YA K+++K+KI + E +E IL L+ P ++ Sbjct: 163 QRLLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFED--HEMTILRKLDHPNIIK 220 Query: 122 MKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYR 181 + + + + GG++FS+L K+G E + F Q++ L+YLH +++R Sbjct: 221 VNMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKYLHEQNIIHR 280 Query: 182 DLKPENILI----DRTGYIKITDFGFCKLIR--GRTWTLCGTPEYLAPEIIL-------- 227 DLK ENILI D I +TDFG + ++ R T GTPEY APEI Sbjct: 281 DLKLENILIASSSDTIFRIILTDFGVARCMQKGKRLSTFVGTPEYTAPEIQRLKGRSQVE 340 Query: 228 ---SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284 S GYG VD WSLGV++F + +G+ P FA + EK V + S + KD+ Sbjct: 341 KENSSGYGKEVDLWSLGVIMFLLLSGNSPSFADG---VKEKQVDFRDPVWKSVSRQAKDL 397 Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWF 313 I ++L+ + R+ T+K + +H WF Sbjct: 398 ISNLLKTNPPDRF-TVKQCL----SHPWF 421 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 129 bits (311), Expect = 7e-31 Identities = 69/189 (36%), Positives = 111/189 (58%), Gaps = 6/189 (3%) Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDKS----ESNAKLNDFERQKVLGTGAFGIVFLVKH 78 +SP +E+ ++KK ++ S + + FE+ +LG G G V+LV+ Sbjct: 155 FSPHGKEKELAHIKKTVATRARTYSSNSIKICDVEVGPSSFEKVFLLGKGDVGRVYLVRE 214 Query: 79 IVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPF 138 +GK+YAMK+L K+++++ + + ++ E+ IL N PF+V + + F+ + YLY + + Sbjct: 215 KKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPFIVTLYHSFQSDEYLYLCMEY 274 Query: 139 IAGGEMFSHL-RKMGK-FEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYI 196 GGE F L R+ G+ E AKFY A+V ALEYLH +YRDLKPENIL+ +G+I Sbjct: 275 CMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGFIYRDLKPENILLHESGHI 334 Query: 197 KITDFGFCK 205 ++DF K Sbjct: 335 MLSDFDLSK 343 Score = 72.1 bits (169), Expect = 1e-13 Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 8/130 (6%) Query: 210 RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMR-----IYE 264 RT + GT EY+APE+I G+ +VDWW+LG+L +EM PF + +++ Sbjct: 378 RTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNILHK 437 Query: 265 KIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNS 324 ++ +Y S K++I +L D R G+ + G D K H +F+ + W L Sbjct: 438 DVIFPEYADAPSISSLCKNLIRKLLVKDENDRLGS-QAGAADVKLHPFFKNVQW--ALLR 494 Query: 325 RIHPPFFPKI 334 PP PK+ Sbjct: 495 HTEPPIIPKL 504 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 123 bits (296), Expect = 5e-29 Identities = 78/247 (31%), Positives = 123/247 (49%), Gaps = 10/247 (4%) Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEK-IVRLKQIEHSYYEKKILCGLN 115 N + + LG+G+FG+V+ + V+G A+K ++ E I + IE + +L N Sbjct: 7 NSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVF---MLSNCN 63 Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175 V+ F D L+ ++ + GG + S L KMG+ E +V+ L YLH Sbjct: 64 SSNVIQYYGCFVDGYTLWILMEHMDGGSV-SGLLKMGRLNEQVISIILREVLYGLNYLHG 122 Query: 176 CELVYRDLKPENILIDR-TGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231 ++RD+K NIL+ TG +K+ DFG + R T GTP ++APE+I Y Sbjct: 123 QNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTSY 182 Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMR-IYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290 G++ D WSLG+ EM+ G PP PMR I+E + + HFS +D + L Sbjct: 183 GLAADIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSEPPKLDDHFSPTFRDFVSCCLD 242 Query: 291 VDTTRRY 297 ++ R+ Sbjct: 243 LNPNMRW 249 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 123 bits (296), Expect = 5e-29 Identities = 75/240 (31%), Positives = 125/240 (52%), Gaps = 8/240 (3%) Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI--LCGLNFPFV 119 ++ LG G+FG V L H T + A+K + ++ + K H E++I L L P + Sbjct: 37 RETLGEGSFGKVKLATHYKTQQKVALKFISRQLLK--KSDMHMRVEREISYLKLLRHPHI 94 Query: 120 VYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELV 179 + + + V+ + AGGE+F ++ + + E + + Q+I A+EY H ++V Sbjct: 95 IKLYDVITTPTDIVMVIEY-AGGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIV 153 Query: 180 YRDLKPENILIDRTGYIKITDFGFCKLIRGRTW--TLCGTPEYLAPEIILSKGY-GMSVD 236 +RDLKPEN+L+D +KI DFG ++ + T CG+P Y APE+I K Y G VD Sbjct: 154 HRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVD 213 Query: 237 WWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR 296 WS G++L+ M G PF +++K+ + Y P S + +I ++ D +R Sbjct: 214 VWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMIVADPMQR 273 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 122 bits (294), Expect = 8e-29 Identities = 74/236 (31%), Positives = 123/236 (52%), Gaps = 5/236 (2%) Query: 65 LGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKY 124 LG+G L KH TG+ +K + + Q E +L + P V+ + Sbjct: 16 LGSGGPNSSRLAKHRETGQLAVVKPIVGWSELTSSQQARIEGELVLLRLIEHPNVLQLID 75 Query: 125 YFKDNVYLYYVLPFIAGGEMFSHLRKMGKF-EETSAKFYGAQVILALEYLHACELVYRDL 183 L+ V+ ++ GGE+F + + G F E+ +AKF Q++ LEY H + +RDL Sbjct: 76 VISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLW-QILCGLEYCHKLHICHRDL 134 Query: 184 KPENILIDRTGYIKITDFGFCKLIR-GR-TWTLCGTPEYLAPEIILSKGY-GMSVDWWSL 240 KPEN+ +D G IKI +FG + + G+ T CG+P Y +PEII+ + Y G + D WS Sbjct: 135 KPENLYLDAHGSIKIGEFGMASIQQPGKLLQTSCGSPHYASPEIIMGRSYDGCASDIWSC 194 Query: 241 GVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR 296 G++ F + G PF + + K+ G++ PS+ S + + ++ +L VD++ R Sbjct: 195 GIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPSNISPQAQHLLYRMLDVDSSTR 250 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 121 bits (292), Expect = 1e-28 Identities = 79/238 (33%), Positives = 119/238 (50%), Gaps = 11/238 (4%) Query: 63 KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYM 122 K LGTG+ V L KH TG A+K++ +R I ++L P ++ + Sbjct: 16 KTLGTGSTSCVRLAKHAKTGDLAAIKIIP----IRYASIGMEILMMRLL---RHPNILRL 68 Query: 123 KYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRD 182 + D+ ++Y L ++ GE+F ++RK G E A Y +Q++ A+ + H +RD Sbjct: 69 YDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRFRFRHRD 128 Query: 183 LKPENILID-RTGYIKITDFGFCKLIRGRTW--TLCGTPEYLAPEIILSKGY-GMSVDWW 238 LK ENILI IKI DFG + + CG+ YLAPEI+ K Y G D W Sbjct: 129 LKLENILIKVNEQQIKIADFGMATVEPNDSCLENYCGSLHYLAPEIVSHKPYRGAPADVW 188 Query: 239 SLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR 296 S GV+L+ + + PF + IY KI G Y PS S +D++ +L V+ + R Sbjct: 189 SCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPSSISSAAQDLLHRMLDVNPSTR 246 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 121 bits (291), Expect = 2e-28 Identities = 79/269 (29%), Positives = 129/269 (47%), Gaps = 9/269 (3%) Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107 +K N + + + LG G V L KH T + A+KM+ +++ + E Sbjct: 12 EKDSGNTYVGPWLLGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKRLQRE 71 Query: 108 KKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167 IL L+ P ++ + F+ Y L ++ ++ S + K + +E + + Q++ Sbjct: 72 VTILRQLHHPNIITLYQVFRVPKYTVLALEYM-DTDLHSMVVKHNRLDECTTRKIFRQIV 130 Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW--TLCGTPEYLAPEI 225 A++Y H + +RDLK ENIL+++ +K+TDFG + ++ T CGTP Y APE+ Sbjct: 131 HAIDYCHLHRVAHRDLKLENILLNKDLVVKLTDFGLSNFMLDGSFLSTSCGTPHYAAPEV 190 Query: 226 ILSKGY-GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284 I + Y G VD W G+LL+ M G PF + ++ G Y PS S D+ Sbjct: 191 IQGRYYDGCDVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGIYTIPSFVSSSASDL 250 Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWF 313 I +L V T R +K V + H WF Sbjct: 251 IRQMLMVLPTSR---IK--VAEIMQHPWF 274 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 120 bits (290), Expect = 2e-28 Identities = 78/259 (30%), Positives = 126/259 (48%), Gaps = 12/259 (4%) Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLK-QIEHSYY 106 D S+ + F + LG GA G V+L K +V GK + K + L+ Q Sbjct: 298 DSVTSHDPVEYFNVKHKLGQGASGSVYLAK-VVGGKQLGIFDSVAIKSIDLQCQTRKELI 356 Query: 107 EKKILC---GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYG 163 +I ++ V Y+ + +L+ V+ ++ G + + K K E Sbjct: 357 LNEITVMRESIHPNIVTYLDSFLVRERHLWVVMEYMNAGSLTDIIEK-SKLTEAQIARIC 415 Query: 164 AQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRT---WTLCGTPEY 220 + +++LHA +++RD+K +N+L+D +G IKITDFGFC + RT T+ GTP + Sbjct: 416 LETCKGIQHLHARNIIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRVTMVGTPYW 475 Query: 221 LAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMR---IYEKIVAGKYRCPSHF 277 +APE++ YG VD WSLG+++ EM PP+ DP+R + K + P+ Sbjct: 476 MAPEVVKQNEYGTKVDIWSLGIMIIEMIENEPPYLREDPIRALYLIAKNGTPTLKKPNLV 535 Query: 278 SVELKDIIGHVLQVDTTRR 296 S LK + L +DT R Sbjct: 536 SKNLKSFLNSCLTIDTIFR 554 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 117 bits (282), Expect = 2e-27 Identities = 59/153 (38%), Positives = 91/153 (59%), Gaps = 2/153 (1%) Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116 + FE+ ++LG G G V+LV+ + +AMK+L K ++++ ++ E++IL Sbjct: 153 HSFEKIRLLGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKH 212 Query: 117 PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGK--FEETSAKFYGAQVILALEYLH 174 PF+V + + F+ YLY + + AGGE F L + K E A FY A+V ALEYLH Sbjct: 213 PFIVTLYHSFQSRDYLYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLH 272 Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLI 207 +YRDLKPENIL+ ++G+I ++DF K I Sbjct: 273 LMGFIYRDLKPENILLHQSGHIMLSDFDLSKPI 305 Score = 83.8 bits (198), Expect = 3e-17 Identities = 47/130 (36%), Positives = 73/130 (56%), Gaps = 8/130 (6%) Query: 210 RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF-----FASDPMRIYE 264 RT + GT EY+APE+I S G+ ++VDWW+LG+ ++E+ G PF A+ +Y Sbjct: 338 RTNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKGKNRHATFSNILYS 397 Query: 265 KIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNS 324 + +Y + S K +I +L D ++R G++ G D K H +FR I W ++L S Sbjct: 398 DVSFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVA-GASDIKQHPFFRHIQW-ALLRS 455 Query: 325 RIHPPFFPKI 334 + PP PKI Sbjct: 456 -MKPPIIPKI 464 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 116 bits (279), Expect = 5e-27 Identities = 69/228 (30%), Positives = 122/228 (53%), Gaps = 12/228 (5%) Query: 36 KKLRQDFVESWDDKSESNAK-LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEK 94 K ++ D E+++D + +N + ++ F+ + V+G G++ VF+VKH T + +A+K + K+K Sbjct: 7 KSVKND-KENFEDPNATNFESVSQFKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKKK 65 Query: 95 IVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKF 154 K I+ E +L LN P + F+D +Y V + GG++ H+ + KF Sbjct: 66 HDEHK-IKKLRNEVLLLQSLNHPLLCKFYSEFEDETKIYLVTDLMLGGDLRYHISQR-KF 123 Query: 155 EETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR------ 208 E+ + + +++ AL Y+H+ +++RD+KP+NIL+D G+ K+ DF + Sbjct: 124 NESVIRIWMVELVSALIYIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPS 183 Query: 209 --GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF 254 T GTP Y+APE ++ DWWSLG+ +E PF Sbjct: 184 KSNMTVGRVGTPVYMAPETLIHAVSYKESDWWSLGITFYECLFQVRPF 231 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 115 bits (277), Expect = 9e-27 Identities = 74/241 (30%), Positives = 126/241 (52%), Gaps = 9/241 (3%) Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG--LNFPFV 119 +K +G G+ G V LV +I+TG+ A+KM+ + + +++ L G L P + Sbjct: 56 KKTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTVR---VQREALLGRLLRHPNI 112 Query: 120 VYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELV 179 + + Y + ++ GG++ ++ GK +E A+ + Q+I AL YLH +V Sbjct: 113 CRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLHKNFIV 172 Query: 180 YRDLKPENILIDR-TGYIKITDFGFCKLIR--GRTWTLCGTPEYLAPEIILSKGY-GMSV 235 +RDLK EN+L+ + + +K+ DFG T CG+ + APE++ +K Y G V Sbjct: 173 HRDLKIENVLLTQDSRQVKLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDAKPYIGPEV 232 Query: 236 DWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTR 295 D WSLGV+++ M G PF ++ KI +GK PS+ S + +I +L V+ + Sbjct: 233 DVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPSYISEDCCSLIAAMLNVNPRK 292 Query: 296 R 296 R Sbjct: 293 R 293 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 114 bits (274), Expect = 2e-26 Identities = 66/205 (32%), Positives = 104/205 (50%), Gaps = 9/205 (4%) Query: 63 KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYM 122 +++G G+FG VF + + + K A+K+++ + QIE E L LN + Sbjct: 10 QLIGQGSFGSVFRAQDVESSKIVALKVVDLD--ATKDQIETLTQEINFLIDLNSVHIT-- 65 Query: 123 KYY--FKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVY 180 KYY F D L+ + + GG L+ G F E QV+ AL YLH ++ Sbjct: 66 KYYASFVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMH 125 Query: 181 RDLKPENILIDRTGYIKITDFGFC---KLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDW 237 RD+K NIL + G +K+ DFG + +R + GTP ++APE++ GY D Sbjct: 126 RDIKAANILTMKDGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVVKQTGYNYKADI 185 Query: 238 WSLGVLLFEMSAGHPPFFASDPMRI 262 WSLG+ +E++ G PP+ PM++ Sbjct: 186 WSLGITAYELATGEPPYSGIHPMKV 210 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 114 bits (274), Expect = 2e-26 Identities = 72/239 (30%), Positives = 118/239 (49%), Gaps = 3/239 (1%) Query: 65 LGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKY 124 LG GAFG V+ +I G+ A+K ++ K+++ + E +L L+ P +V + Sbjct: 15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLK-SDLSVIKMEIDLLKNLDHPNIVKYRG 73 Query: 125 YFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLK 184 ++ N L +L + G + S + GK E Y QV+ L YLH +++RD+K Sbjct: 74 SYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIK 133 Query: 185 PENILIDRTGYIKITDFGFCKLIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVL 243 NIL + G IK+ DFG I ++ G+P ++APE+I G + D WS+G Sbjct: 134 GANILTTKDGTIKLADFGVATKINALEDHSVVGSPYWMAPEVIELVGATTASDIWSVGCT 193 Query: 244 LFEMSAGHPPFFASDPMRIYEKIVAGKY-RCPSHFSVELKDIIGHVLQVDTTRRYGTLK 301 + E+ G+PP++ DP ++V ++ PS+ S K + Q D R T K Sbjct: 194 VIELLDGNPPYYDLDPTSALFRMVKDEHPPLPSNISSAAKSFLMQCFQKDPNLRIKTRK 252 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 112 bits (270), Expect = 6e-26 Identities = 55/160 (34%), Positives = 95/160 (59%), Gaps = 1/160 (0%) Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107 + + + +ND++ K + GAFG V+L + TG Y+A+K+L+K ++ Q+ + E Sbjct: 578 NSAPEHPSINDYKILKPISKGAFGSVYLAQKRTTGDYFAIKILKKSNMIAKNQVINVRAE 637 Query: 108 KKILCGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166 + IL PFV + Y F+ YLY V+ ++ GG+ S L+ MG + + Y A+ Sbjct: 638 RAILMSQGESPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAET 697 Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL 206 +L L LH +++RD+KPEN+LI + G++K+TDFG ++ Sbjct: 698 VLCLGDLHDRGIIHRDIKPENLLISQNGHLKLTDFGLSRV 737 Score = 102 bits (245), Expect = 7e-23 Identities = 53/133 (39%), Positives = 79/133 (59%), Gaps = 8/133 (6%) Query: 216 GTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPS 275 GTP+Y+APE+IL + DWWSLG ++FE G+PPF A P ++++ I+A + P+ Sbjct: 859 GTPDYIAPEVILGNPGIKASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNILARRINWPA 918 Query: 276 H-FSVELK---DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFF 331 F+ E D+I +L ++ R G +GV + K H +F+ ++WD+IL PPF Sbjct: 919 EVFTAESSVALDLIDRLLCMNPANRLGA--NGVEEIKAHPFFKSVNWDTILEE--DPPFV 974 Query: 332 PKIRSPGDTTNFD 344 PK SP DT FD Sbjct: 975 PKPFSPEDTVYFD 987 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 111 bits (268), Expect = 1e-25 Identities = 56/152 (36%), Positives = 90/152 (59%), Gaps = 1/152 (0%) Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115 + D+E K + G FG V+L + TG+ YA+K+L K ++ Q+ + E+ +L Sbjct: 561 IQDYEIIKPISKGTFGTVYLSRKNTTGEIYAIKVLRKVDMISKNQVANVKAERAVLMAQE 620 Query: 116 -FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174 FV + Y F+ YLY V+ F+ GG+ S L+ + E+ AK Y A+V L LE+LH Sbjct: 621 ESAFVAKLYYAFQSRDYLYLVMEFMNGGDCASLLKSLYTIPESWAKIYIAEVALGLEHLH 680 Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKL 206 +++RD+KP+NIL+ TG++K+ DFG +L Sbjct: 681 RLGIIHRDIKPDNILMSITGHLKLADFGLSQL 712 Score = 93.1 bits (221), Expect = 6e-20 Identities = 51/133 (38%), Positives = 68/133 (51%), Gaps = 8/133 (6%) Query: 216 GTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPS 275 GTP+YLAPE + VDWW+LG +LFE G+PPF A P +++E I+A P Sbjct: 833 GTPDYLAPETLRGSTQDDMVDWWALGCVLFEFLFGYPPFHAETPEKVFENILANNIAWPD 892 Query: 276 ----HFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFF 331 S E D+I LQ + RR G + + K H +F I+WD I + PF Sbjct: 893 LEMYPCSEEALDLINGFLQPNPERRLGF--SDINEIKEHPFFNGINWDDIFSH--EAPFI 948 Query: 332 PKIRSPGDTTNFD 344 P +P DT FD Sbjct: 949 PAPETPLDTAYFD 961 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 110 bits (265), Expect = 3e-25 Identities = 53/159 (33%), Positives = 90/159 (56%) Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108 K + + + F+ LG G +G V+L K T + AMKM++K + +L +++H E+ Sbjct: 152 KKRTKIQCSHFDLLVKLGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNER 211 Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168 IL N ++V + Y F+D +Y + ++ GG+ + L G E +FY A+++ Sbjct: 212 DILTNTNSEWLVKLYYAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVA 271 Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI 207 A+ +H ++RDLKPEN LID+ G+IK++DFG I Sbjct: 272 AISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAI 310 Score = 78.6 bits (185), Expect = 1e-15 Identities = 48/164 (29%), Positives = 83/164 (50%), Gaps = 20/164 (12%) Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK-- 270 ++ G+PEY+APE++ K Y +VD+WSLG + +E G+PPF S + + + Sbjct: 356 SVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGYPPFSGSTLQETWTNLYYWREM 415 Query: 271 YRCPS------------HFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDW 318 + PS S E I L T+R T ++ + H +F+ + W Sbjct: 416 LQRPSKNENGIYDKKARSVSDEAWSFITKCLTEPTSRFQST-----IEIQKHPFFKRLHW 470 Query: 319 DSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEE 362 + L R PPF P++ + DT+ FD F++E++ D+ +YE++ Sbjct: 471 NG-LRKRAVPPFVPRLENQLDTSYFDDFNDEQVLDAYKDVYEKQ 513 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 107 bits (256), Expect = 3e-24 Identities = 73/244 (29%), Positives = 121/244 (49%), Gaps = 22/244 (9%) Query: 65 LGTGAFGIVFLVKHIVTGKYYAMKML------EKEKIVRLKQIEHSYYEKKILCGLNFPF 118 +G GA G V+ + + T A+K + +KE IV + S++ K I+ NF Sbjct: 392 IGQGASGDVYSARQVGTNLSVAIKKMNINQQPKKEFIVNEILVMKSHHHKNIV---NF-- 446 Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178 +++K +++ V+ ++ GG + + + E + + L++LH + Sbjct: 447 --IDTFFYKSELWM--VMEYMRGGSL-TEVVTNNTLSEGQIAAICKETLEGLQHLHENGI 501 Query: 179 VYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGYGMSV 235 V+RD+K +NIL+ G IK+TDFGFC I + T+ GTP ++APE++ K YG V Sbjct: 502 VHRDIKSDNILLSLQGDIKLTDFGFCAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYGFKV 561 Query: 236 DWWSLGVLLFEMSAGHPPFFASDPMR---IYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292 D WSLG++ EM G PP+ +P+R + I K P S D + L V+ Sbjct: 562 DVWSLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPKISRPELLSSVFHDFLSKSLTVN 621 Query: 293 TTRR 296 +R Sbjct: 622 PKQR 625 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 107 bits (256), Expect = 3e-24 Identities = 51/154 (33%), Positives = 86/154 (55%) Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108 K + DF+ +G G +G V+L + T + A+K++ K + ++ +I H E+ Sbjct: 198 KRRTRISHGDFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSVLHKMDEIRHVLTER 257 Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168 IL N ++V + Y F+D +Y + F+ GG+ + L G + AKFY ++ L Sbjct: 258 DILTTANSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGVLRDHHAKFYATEMFL 317 Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202 A++ LH ++RDLKPEN L+ +G+IK+TDFG Sbjct: 318 AIDALHQLGYIHRDLKPENFLVGASGHIKLTDFG 351 Score = 70.9 bits (166), Expect = 3e-13 Identities = 43/148 (29%), Positives = 71/148 (47%), Gaps = 17/148 (11%) Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK-- 270 ++ G+P+Y+APE++ + Y SVD+WSLG +++E +G PPF S+ + + + Sbjct: 402 SVVGSPDYMAPEVLRGENYNHSVDYWSLGCIMYECLSGFPPFSGSNVNETWSNLKNWRKC 461 Query: 271 -----YRCPSHFSVELK----DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSI 321 Y P + D + H + D R+ +LK H +F +IDW ++ Sbjct: 462 FQRPHYDDPRDLEFNWRDDAWDFVCHCI-TDPKDRFCSLK----QVMQHPYFSKIDWKNV 516 Query: 322 LNSRIHPPFFPKIRSPGDTTNFDVFDEE 349 + PPF P + S D FD F E Sbjct: 517 -RTAYRPPFVPDLNSEIDAGYFDDFTNE 543 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 107 bits (256), Expect = 3e-24 Identities = 69/226 (30%), Positives = 115/226 (50%), Gaps = 14/226 (6%) Query: 63 KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIV-------RLKQIEHSYYEKKILCGLN 115 +++G G +G VFL +I TG+ A+K +E + + R ++ E ++ L+ Sbjct: 829 ELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRKDIVDSINAEISMIADLD 888 Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175 +V + K + L +++GG + LR G FEE +F QV+ L YLH+ Sbjct: 889 HLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRFVSRQVLYGLSYLHS 948 Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK-----LIRGRTWTLCGTPEYLAPEIILS-- 228 +++RDLK +N+LID G KI+DFG K ++ G+ ++APE+I + Sbjct: 949 KGIIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDH 1008 Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP 274 +GY VD WSLG ++ EM AG P+ + ++ K+ K P Sbjct: 1009 QGYSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAMFKLGTEKKAPP 1054 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 102 bits (245), Expect = 7e-23 Identities = 77/279 (27%), Positives = 137/279 (49%), Gaps = 25/279 (8%) Query: 53 NAKLND---FERQKVLGTGAFGIVFLVKHIVTGKYYAMKM-LEKEKIVRLKQIEHSYYEK 108 N +++D + + V+G G+FG V+L H++T +K K+ I+ ++I H + Sbjct: 22 NPRISDVGTYRIESVVGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAIILAREIHH---HR 78 Query: 109 KILCGLNFPFV--VYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166 ++L P + +Y +D +YL + + GE++ + + + +E + Q+ Sbjct: 79 RLL----HPNITRLYEVVCTEDRIYL--AMEYCPNGELYDWVAREKRLDEKTTCRIMWQL 132 Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW--TLCGTPEYLA 222 A++YLH V+RDLK ENI +D+ +K+ DFGF + RT+ T CGT Y A Sbjct: 133 CCAIQYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRTFMNTRCGTVAYCA 192 Query: 223 PEIILSKGY-GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVEL 281 PE++ Y G VD WSLG++++ + G PF D +KI+ + P S Sbjct: 193 PELVQGHKYIGECVDIWSLGIIMYALLIGRLPFDEDDVSLTEQKIINECPQYPETLSKNS 252 Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDS 320 ++ +L D L+ + +H +F+E + S Sbjct: 253 SSLLKSLLCKDY-----RLRPSIDQIISHPYFKENGYHS 286 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 102 bits (244), Expect = 9e-23 Identities = 52/148 (35%), Positives = 88/148 (59%), Gaps = 1/148 (0%) Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115 L++F K + GA+G V+L K +GKY+A+KM+ K + LK+I+ EK+ + Sbjct: 525 LDEFILLKEINRGAYGRVYLAKKRSSGKYFALKMIPKSSLDSLKKIKGLLLEKRNMHIQR 584 Query: 116 F-PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174 + P V + Y F YL V+ + GG+ + ++K+G E Y A+++ A+E LH Sbjct: 585 YGPNTVKLYYAFDSGDYLCLVMDYFNGGDCETLIQKLGPLPEQWVCQYAAELLNAIELLH 644 Query: 175 ACELVYRDLKPENILIDRTGYIKITDFG 202 +++ D+KP N+L+D TG+I++TDFG Sbjct: 645 QDGIIHHDIKPANMLVDETGHIRLTDFG 672 Score = 72.1 bits (169), Expect = 1e-13 Identities = 46/135 (34%), Positives = 70/135 (51%), Gaps = 9/135 (6%) Query: 214 LCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKI----VAG 269 + GTP Y+APEI++ M D W++G ++FEM G PF A+ I+ +I + Sbjct: 777 ISGTPNYMAPEILMGVDTQMG-DIWAMGCVIFEMLTGTRPFEANTVKAIWARIERNDIGW 835 Query: 270 KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPP 329 R S E D+I ++ D +R G+ +G + K H +FR I WD+ LNS P Sbjct: 836 TKRVKESCSKEAVDLITKLMDPDCNKRLGS--NGYQEIKKHPFFRTIKWDN-LNSG-PGP 891 Query: 330 FFPKIRSPGDTTNFD 344 F P+ + D T F+ Sbjct: 892 FVPQTENVEDLTYFE 906 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 98.3 bits (234), Expect = 1e-21 Identities = 69/254 (27%), Positives = 124/254 (48%), Gaps = 11/254 (4%) Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110 E+N + + + +++G G++G V+ +T + A+K+L + ++ E + Sbjct: 2 ENNTASSPYTKLELVGRGSYGAVYRGICNLTKETVAIKILNLD--TDEDEVSDIQKEVAV 59 Query: 111 LCGLNFPFVV-YMKYY--FKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167 L L V +KY+ + L+ ++ + GG + + L + G E + + Sbjct: 60 LSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGSVRT-LMEAGPISEPCISLILRETL 118 Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFC---KLIRGRTWTLCGTPEYLAPE 224 AL+++H +++RD+K NIL+ +G +K+ DFG + R + T GTP ++APE Sbjct: 119 QALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPE 178 Query: 225 IIL-SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMR-IYEKIVAGKYRCPSHFSVELK 282 +I + Y + D WSLG+ +E++ G PP DP R +Y R +FS LK Sbjct: 179 VIRDGQEYNVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIAHTAPPRLNGNFSALLK 238 Query: 283 DIIGHVLQVDTTRR 296 + I LQ RR Sbjct: 239 EFIASCLQDVPQRR 252 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 97.5 bits (232), Expect = 3e-21 Identities = 68/213 (31%), Positives = 110/213 (51%), Gaps = 16/213 (7%) Query: 55 KLNDFERQ--KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIE------HSYY 106 KL++F + +GTGAF V L + K YA+K + K+ S Sbjct: 4 KLDNFPYHIGREIGTGAFASVRLC-YDDNAKIYAVKFVNKKHATSCMNAGVWARRMASEI 62 Query: 107 EKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166 + LC +++ ++ + + VL F GG++F + +E A+FY AQ+ Sbjct: 63 QLHKLCN-GHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQL 121 Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTL---CGTPEYL 221 + + ++H+ + +RDLKPENIL+D G +KI+DFGF L +G++ L G+P Y Sbjct: 122 MEGISFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYA 181 Query: 222 APEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF 254 APE I + G VD WS G++LF + G+ P+ Sbjct: 182 APE-ITQQYDGSKVDVWSCGIILFALLLGNTPW 213 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 96.7 bits (230), Expect = 5e-21 Identities = 75/254 (29%), Positives = 119/254 (46%), Gaps = 21/254 (8%) Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKML-----EKEKIVRLKQIEHSYYEKKILCGLN 115 R ++G+G+FG V+L + +G+ A+K + + K K ++ E +L L+ Sbjct: 396 RGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELS 455 Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175 +V ++ +L L ++ GG + L G FEET K + Q + LEYLH+ Sbjct: 456 HEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHS 515 Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIR---------GRTWTLCGTPEYLAPEII 226 +V+RD+K NIL+D G IKI+DFG K + G + G+ ++APE++ Sbjct: 516 RGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVV 575 Query: 227 LSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPM----RIYEKIVAGKYRCPSHFSVELK 282 + D WSLG L+ EM P+ D M RI E I+ PS+ S Sbjct: 576 KQTMHTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRIGENILP---EFPSNISSSAI 632 Query: 283 DIIGHVLQVDTTRR 296 D + +D R Sbjct: 633 DFLEKTFAIDCNLR 646 >SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Schizosaccharomyces pombe|chr 3|||Manual Length = 830 Score = 96.3 bits (229), Expect = 6e-21 Identities = 68/263 (25%), Positives = 128/263 (48%), Gaps = 42/263 (15%) Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108 ++ +N + + + +G G+F IV+ KH T + ++K + +K+ + K +E+ E Sbjct: 4 QTSTNQTIGPYVIRSEIGRGSFAIVYKGKHTETNRVISIKSVLTKKLTK-KLLENLESEI 62 Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFE------------- 155 IL + VV + K +++ V+ + + G++ +RK KF Sbjct: 63 SILKEIRHVHVVELIDCIKAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDHP 122 Query: 156 --------ETSAKFYGAQVILALEYLHACELVYRDLKPENILID---------------- 191 ET + + Q+ AL++L + L++RD+KP+N+L+ Sbjct: 123 PVYKAGLNETLVRHFTQQLASALQFLRSRSLIHRDVKPQNLLLQPPPTAAYLEEHPQFVG 182 Query: 192 --RTGYIKITDFGFCKLIRGRTW--TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEM 247 + +K+ DFGF + ++ + TLCG+P Y+APEI+ + Y D WS+G +L+EM Sbjct: 183 SPKLPMLKLADFGFARYLQTSSMAETLCGSPLYMAPEILRYEKYDAKADLWSVGAVLYEM 242 Query: 248 SAGHPPFFASDPMRIYEKIVAGK 270 + G PPF A + + + +I K Sbjct: 243 AVGKPPFKAPNHVELLRRIQKAK 265 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 94.7 bits (225), Expect = 2e-20 Identities = 88/302 (29%), Positives = 143/302 (47%), Gaps = 35/302 (11%) Query: 36 KKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK-EK 94 KK+R+ F D+ +N +E K LG G G V L + VT + A+K++ K E+ Sbjct: 117 KKIRKRF-----DRFSGRKYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTER 171 Query: 95 IVRLKQIEHSYYEKK------ILCGLNFPFVVYMKYYFKD--NVYLYYVLPFIAGGEMFS 146 +L + S ++K IL P VV ++ D + +Y VL +++GGE+ Sbjct: 172 RPKLGRANASSQKEKVRREIAILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPW 231 Query: 147 HLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL 206 + A+ Y V+L LEYLH +++RD+KP N+L++ + +KI+DFG + Sbjct: 232 TDCDSPVLSISEARQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYI 291 Query: 207 IRG--------RTWTLCGTPEYLAPEIILS------KGYGMSVDWWSLGVLLFEMSAGHP 252 GTP + APE+ + ++D W+LGV LF + G Sbjct: 292 ANAGLNEDNDVELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRC 351 Query: 253 PFFASDPMRIYEKIVAGKYRCPS--HFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNH 310 PF AS +++KIV + PS E +D++ +L D +R TL ++ K H Sbjct: 352 PFNASMEYELFDKIVNERLNIPSTPDIGEEGRDLLKRLLCKDPEQRI-TL----VEVKLH 406 Query: 311 KW 312 W Sbjct: 407 PW 408 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 93.9 bits (223), Expect = 3e-20 Identities = 68/211 (32%), Positives = 108/211 (51%), Gaps = 22/211 (10%) Query: 67 TGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQ-IEHSYYEKKILCGLNFPFVV--YMK 123 +G FG V+ ++ TG A+K ++ + + ++ + E +L LN P VV Y Sbjct: 1045 SGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLNHPNVVTYYGV 1104 Query: 124 YYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSA-KFYGAQVILALEYLHACELVYRD 182 ++ VY++ + F GG + + L G+ E+ + K Y Q++ L Y+H+ +++RD Sbjct: 1105 EVHREKVYIF--MEFCQGGSL-ADLLAHGRIEDENVLKVYVVQLLEGLAYIHSQHILHRD 1161 Query: 183 LKPENILIDRTGYIKITDFGFCKLIRGRT-------------WTLCGTPEYLAPEIIL-- 227 +KP NIL+D G IK +DFG + T L GTP Y+APEIIL Sbjct: 1162 IKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYMAPEIILGT 1221 Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPFFASD 258 KG ++D WSLG ++ EM G P+ D Sbjct: 1222 KKGDFGAMDIWSLGCVILEMMTGSTPWSEMD 1252 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 93.1 bits (221), Expect = 6e-20 Identities = 86/283 (30%), Positives = 126/283 (44%), Gaps = 37/283 (13%) Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGK---YYAMKMLEKEKIVRLKQ---IE 102 KS N + + +GTG FG V L + + + + + ++ KQ Sbjct: 482 KSTKNYTFGSYILGRTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNCQTS 541 Query: 103 HSYYEKKILCGL--NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAK 160 E IL GL N P +V + K + VL ++ GGE+F ++ + E++ A Sbjct: 542 RLMREVAILKGLGNNHPHIVKYLDFVKTKHHFGIVLDYVNGGELFDYILARRRLEDSVAC 601 Query: 161 FYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTL------ 214 AQ+I + YLH+ +V+RDLK ENIL+D I I DFGF G TL Sbjct: 602 RLFAQLISGVAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTF-GHFNTLSEHSLP 660 Query: 215 ----------CGTPEYLAPEIILSKG---YGMSVDWWSLGVLLFEMSAGHPPFFASDP-- 259 CG+P Y APE++ K G D WS GV+L+ M AG+ P F DP Sbjct: 661 TEKPDLFSTSCGSPCYAAPELVNCKSGMYAGTQADIWSCGVILYAMLAGYLP-FDDDPHN 719 Query: 260 ------MRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR 296 R+Y I + P F + +DI+ +L D +R Sbjct: 720 PNGENVPRLYRYICSTPLIFPEFFKSKARDILKKILVPDPAKR 762 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 91.9 bits (218), Expect = 1e-19 Identities = 84/301 (27%), Positives = 146/301 (48%), Gaps = 29/301 (9%) Query: 40 QDFVES-WDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYA-MKMLEKEKIV- 96 +D+V+S W+ + A K LG GA+G V L + + +K + K +I+ Sbjct: 486 EDYVDSEWEVVPHNIASYTTI---KELGIGAYGQVKLATYKSNKVHEVILKSISKSRILL 542 Query: 97 ----RLKQIEHSYYEKKILCGL---NFPFVVYMKYYFKDNVYLYYVL--PFIAGGEMFSH 147 R K + E IL L + P +V M +F+DN YY+L P G ++F + Sbjct: 543 DSWMRDKDLGTVPMEISILHFLKAHSHPNIVKMITFFEDNEN-YYLLTEPQKPGIDLFDY 601 Query: 148 LRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI 207 + E +K Q+ LA+ +LH+ ++++RD+K EN++++ G ++ DFG L Sbjct: 602 IELKPSISEKESKAIFFQIALAVAHLHSFDIIHRDIKDENVILEGNGCARLIDFGSSSLT 661 Query: 208 R-GRTWTLCGTPEYLAPEIILSKGY-GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK 265 + G T GT + APE++ + Y G D W+LG+LL+ + + +P E+ Sbjct: 662 KNGPFDTFRGTVGFAAPELLRGEKYLGKEQDIWALGILLYTI------VYRENPYYNIEE 715 Query: 266 IVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSR 325 I+ K R P S + D+I +L + R T+++ + H WF +I + + R Sbjct: 716 ILDAKLRIPFELSKDNVDLICRMLDRNVHDRI-TIEETL----QHHWFDDIRYLDTSHIR 770 Query: 326 I 326 I Sbjct: 771 I 771 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 88.2 bits (209), Expect = 2e-18 Identities = 60/221 (27%), Positives = 113/221 (51%), Gaps = 22/221 (9%) Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107 D + K +E +VLG+G+FG+V K + T + A+K + ++K + ++++ Sbjct: 14 DGTTGEKKTISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNRELQ----- 68 Query: 108 KKILCGLNFPFVVYMKYYF------KDNVYLYYVLPFIAG---GEMFSHLRKMGKFEETS 158 I+ ++ P ++ + +F KD +L +L ++ +M + R+ S Sbjct: 69 --IMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLS 126 Query: 159 AKFYGAQVILALEYLHACELVYRDLKPENILID-RTGYIKITDFGFCKLI---RGRTWTL 214 K Y Q+ AL YLH+ + +RD+KP+N+L+D +TG +K+ DFG K++ + Sbjct: 127 IKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEPNVSYI 186 Query: 215 CGTPEYLAPEIIL-SKGYGMSVDWWSLGVLLFEMSAGHPPF 254 C + Y APE++ + Y +D WS ++ E+ G P F Sbjct: 187 C-SRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLF 226 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 87.4 bits (207), Expect = 3e-18 Identities = 64/205 (31%), Positives = 101/205 (49%), Gaps = 17/205 (8%) Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIE-HSYYEKKI---LC---GL 114 Q+V+G GAFG+V + H V + + L K R K E Y K++ C L Sbjct: 354 QEVIGRGAFGVV-RIAHKVDPQNSGSETLYAVKEFRRKPAESQKKYTKRLTSEFCISSSL 412 Query: 115 NFPFVVYMKYYFKDNVYLYY-VLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173 P V++ +D Y V+ +GG++++ + G+ E A + Q++ ++YL Sbjct: 413 RHPNVIHTLDLIQDGKGDYCEVMELCSGGDLYTLIMAAGRLEPMEADCFFKQLMRGVDYL 472 Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLIR-------GRTWTLCGTPEYLAPEII 226 H + +RDLKPEN+L+ +G +KITDFG + R T LCG+ Y+APE Sbjct: 473 HDMGVAHRDLKPENLLLTVSGSLKITDFGNGECFRMAWEKEAHMTCGLCGSAPYIAPEEY 532 Query: 227 LSKGYG-MSVDWWSLGVLLFEMSAG 250 + +VD W+ GV+ M G Sbjct: 533 TESEFDPRAVDVWACGVIYMAMRTG 557 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 87.4 bits (207), Expect = 3e-18 Identities = 58/195 (29%), Positives = 96/195 (49%), Gaps = 3/195 (1%) Query: 65 LGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKY 124 +G GAFG+V K +TG A+K + K + + +Y E K+L L ++ + Sbjct: 26 IGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLA-KRTYRELKLLKHLRHENIISLSD 84 Query: 125 YFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLK 184 F Y + + G ++ L E +++ Q++ L+++H+ +++RDLK Sbjct: 85 IFISPFEDIYFVTELLGTDLHRLLTSR-PLETQFIQYFLYQILRGLKFVHSAGVIHRDLK 143 Query: 185 PENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILS-KGYGMSVDWWSLGVL 243 P NILI+ +KI DFG ++ + T Y APEI+L+ + Y + VD WS G + Sbjct: 144 PSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCI 203 Query: 244 LFEMSAGHPPFFASD 258 EM G P F D Sbjct: 204 FAEMIEGKPLFPGRD 218 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 86.6 bits (205), Expect = 5e-18 Identities = 66/224 (29%), Positives = 113/224 (50%), Gaps = 20/224 (8%) Query: 44 ESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEH 103 E+ D S K + KV+G+G+FG+V V I + A+K + ++K + ++++ Sbjct: 17 ETARDGSTGEVKQLSYTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKNRELQ- 75 Query: 104 SYYEKKILCGLNFPFVV-YMKYYF-----KDNVYLYYVLPFIAGGEMFS---HLRKMGKF 154 I+ + P +V + YY+ D VYL VL F+ + + R+ Sbjct: 76 ------IMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSM 129 Query: 155 EETSAKFYGAQVILALEYLHACELVYRDLKPENILID-RTGYIKITDFGFCK-LIRGR-T 211 K Y Q++ +L Y+HA + +RD+KP+N+L+D G +K+ DFG K L+ G Sbjct: 130 PMLEVKLYIYQLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPN 189 Query: 212 WTLCGTPEYLAPEIIL-SKGYGMSVDWWSLGVLLFEMSAGHPPF 254 + + Y APE+I + Y ++D WS G ++ E+ GHP F Sbjct: 190 VSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLF 233 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 84.2 bits (199), Expect = 3e-17 Identities = 72/269 (26%), Positives = 125/269 (46%), Gaps = 33/269 (12%) Query: 60 ERQKVL---GTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116 E+ K+L G G+FG ++ V+ + G A K + I R ++ ++ E IL L Sbjct: 2 EKYKILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEK-QYIADEVNILRNLKH 60 Query: 117 PFVVYM--KYYFKDNVYLYYVLPFIAGGEMFSHLRKMG----KFEETSAKFYGAQVILAL 170 P +V + + + + + G++ + +++ +F E + Q++LAL Sbjct: 61 PNIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLAL 120 Query: 171 EYLH------ACE-------------LVYRDLKPENILIDRTGYIKITDFGFCKLI---R 208 H AC+ +++RD+KP NI +D +K+ DFG KL+ R Sbjct: 121 YRCHYGENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLDNTR 180 Query: 209 GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA 268 T + GTP Y++PEII S Y D W+LG ++FE+ PF + + I Sbjct: 181 VFTQSYVGTPYYMSPEIIRSSPYSAKSDVWALGCVIFEICMLTHPFEGRSYLELQRNICQ 240 Query: 269 GKYRC-PSHFSVELKDIIGHVLQVDTTRR 296 G C H+S ++ +I H L+V++ R Sbjct: 241 GNLSCWDHHYSDDVFLLIRHCLEVNSDLR 269 >SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schizosaccharomyces pombe|chr 1|||Manual Length = 504 Score = 81.4 bits (192), Expect = 2e-16 Identities = 47/126 (37%), Positives = 65/126 (51%), Gaps = 10/126 (7%) Query: 194 GYIKITDFGFCKLI-RGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHP 252 G I I DFGF K++ +T T CGT Y APEI+ + Y +VD W++G +L M G P Sbjct: 232 GRILIADFGFSKVVWNSKTATPCGTVGYAAPEIVNDELYSKNVDMWAMGCVLHTMLCGFP 291 Query: 253 PFFASDPMRIYEKIVAGKYRCPS----HFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFK 308 PFF + + K+V G++ S S KD+I H+L VD RY + F Sbjct: 292 PFFDENIKDLASKVVNGEFEFLSPWWDDISDSAKDLITHLLTVDPRERY-----DIHQFF 346 Query: 309 NHKWFR 314 H W + Sbjct: 347 QHPWIK 352 Score = 62.9 bits (146), Expect = 7e-11 Identities = 40/142 (28%), Positives = 73/142 (51%), Gaps = 2/142 (1%) Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115 L ++ + LG GAF V+ I ++ A+K++ K ++ + KQ + + E I+ + Sbjct: 62 LEKYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNK-KQRQGVFKEVNIMRRVK 120 Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH- 174 VV + + + + + V+ GGE+F + F E A+ QV A+++LH Sbjct: 121 HKNVVNLFDFVETEDFYHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAVKHLHD 180 Query: 175 ACELVYRDLKPENILIDRTGYI 196 C +V+RD+KPEN+L Y+ Sbjct: 181 VCGIVHRDIKPENLLFQPIEYL 202 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 80.2 bits (189), Expect = 4e-16 Identities = 70/240 (29%), Positives = 101/240 (42%), Gaps = 12/240 (5%) Query: 24 SPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLND-FERQKVLGTGAFGIVFLVKHIVTG 82 S Q + S+ K F+E DD N LG G G V + T Sbjct: 43 SKLTQRKESRDSKTFVPSFLEELDDDHLHELVTNGGILYMNSLGEGVSGSVRKCRIRGTQ 102 Query: 83 KYYAMK-MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV--YMKYYFKDNVYLYYVLPFI 139 +AMK +L KQ+ E KI P++V Y Y L + + Sbjct: 103 MIFAMKTVLAAPNTALQKQLLR---ELKINRSCTSPYIVKYYGACYNNAECQLNIAMEYC 159 Query: 140 AGGEM---FSHLRKMG-KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGY 195 G + + +R G + E V+ L YLH ++++RD+KP NIL+ G Sbjct: 160 GAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYLHDRKIIHRDIKPSNILLTSKGQ 219 Query: 196 IKITDFGFC-KLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF 254 +K+ DFG +L+ T GT Y+APE I Y +S D WSLG+ L E++ PF Sbjct: 220 VKLCDFGVSGELVNSLAGTFTGTSYYMAPERISGGSYTISSDIWSLGLTLMEVALNRFPF 279 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 79.8 bits (188), Expect = 6e-16 Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 26/230 (11%) Query: 58 DFERQKVLGTGAFGIVFLVKH---IVTGK-YYAMKMLEKEKIVRLKQIEHSYY---EKKI 110 DF+ K + GA + +V H I K YYA K+ K K K++ Y E I Sbjct: 119 DFQHLKSIAKGATSTIKVVTHRDKITDAKIYYAAKVYRKTKTSHKKRLNTMVYFLREWSI 178 Query: 111 LCGLNFPFV-------VYMKYYFKDNVYLYYVLPFIAGGEMFSHLR-KMGKFEETSAKFY 162 L+ P + V + F + V + G++F + K+ E+ Y Sbjct: 179 QPKLDHPNILKVICPCVTLTSVFNKSAGFCLVQEYCPQGDLFKQIEEKVLTLEDKCC--Y 236 Query: 163 GAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTL------ 214 Q++ A+ YL + + +RDLKPENILI R G +K+TDFG +++ G ++ Sbjct: 237 LKQILQAVAYLQSQRIAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVSGA 296 Query: 215 CGTPEYLAPEIILSKGY-GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIY 263 G+ YLAPE Y G+ D WS G+LL + G+ PF S +Y Sbjct: 297 VGSLAYLAPEAFHENEYCGLLADRWSCGILLKVLFTGYFPFKTSVKTDLY 346 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 78.6 bits (185), Expect = 1e-15 Identities = 64/215 (29%), Positives = 100/215 (46%), Gaps = 12/215 (5%) Query: 43 VESWDDKSESNAKLND----FERQKVLGTGAFGIVFLVKHI--VTGKYYAMKMLEKEKIV 96 + S DD E +D F++ K + F V+ V I T Y +KML+K Sbjct: 269 INSADDYEEEEDWTSDLRIRFQQVKPIHESDFSFVYHVSSINPPTETVYVVKMLKKNA-A 327 Query: 97 RLKQIEHSYYEKKILCGLNF-PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFE 155 + E E IL L PFVV + + N ++ L + G++ L ++G + Sbjct: 328 KFTGKERHLQEVSILQRLQACPFVVNLVNVWSYNDNIFLQLDYCENGDLSLFLSELGLLQ 387 Query: 156 ETSA-KFYGA--QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212 + + Q+ AL ++H E V+ D+KP N+LI R G +K+ DFG + + Sbjct: 388 VMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFGLATSLPVSSM 447 Query: 213 T-LCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFE 246 L G Y+APEI+ S YG D +SLG+ + E Sbjct: 448 VDLEGDRVYIAPEILASHNYGKPADVYSLGLSMIE 482 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 78.6 bits (185), Expect = 1e-15 Identities = 71/237 (29%), Positives = 111/237 (46%), Gaps = 28/237 (11%) Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKML----EKE--KIVRLKQIE--HSYYE 107 L D+ + LG G FG V+ + GK YA+K + EKE I +++I+ S Sbjct: 33 LTDYHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSIKH 92 Query: 108 KKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG-KFEETSAKFYGAQV 166 + I+ L+ VV + +Y V P++ ++ L KF E K Y Q+ Sbjct: 93 ENII-PLSDMTVVRADKKHRRRGSIYMVTPYM-DHDLSGLLENPSVKFTEPQIKCYMKQL 150 Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---------------RGRT 211 +YLH +++RDLK N+LID G +KI DFG ++I R Sbjct: 151 FAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRRE 210 Query: 212 WTLC-GTPEYLAPEIIL-SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKI 266 +T C T Y +PE++L + Y ++D WS+G ++ EM G P S + +KI Sbjct: 211 YTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKI 267 >SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 580 Score = 77.8 bits (183), Expect = 2e-15 Identities = 41/109 (37%), Positives = 58/109 (53%), Gaps = 5/109 (4%) Query: 194 GYIKITDFGFCKLI-RGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHP 252 G I++ DFG K++ T T CGT Y APEI+ + Y VD W+LG +L+ + G P Sbjct: 302 GRIRLADFGLSKVVWDSHTQTPCGTMGYTAPEIVRDERYSKGVDMWALGCVLYTILCGFP 361 Query: 253 PFFASDPMRIYEKIVAGKYRCPS----HFSVELKDIIGHVLQVDTTRRY 297 PF+ + +K+ G+Y S S KD+I H+L VD RY Sbjct: 362 PFYDESISLLTKKVSRGEYSFLSPWWDDISKSAKDLISHLLTVDPESRY 410 Score = 68.1 bits (159), Expect = 2e-12 Identities = 49/184 (26%), Positives = 91/184 (49%), Gaps = 12/184 (6%) Query: 25 PAKQEQYSQYLKKL-RQDFVESWDDKSESNAK-LNDFERQKVLGTGAFGIVFLVKHIVTG 82 P +++Y + ++ L + VE + K L + + +G GAF V+ H TG Sbjct: 88 PTNEKEYDKAIEALVAKAIVEEHSGQQFPVYKGLEQYTLLQKMGDGAFSNVYKAIHNRTG 147 Query: 83 KYYAMKMLEKE------KIVRLKQIEHSYY---EKKILCGLNFPFVVYMKYYFKDNVYLY 133 + A+K++++ + R +Q S+ E +I+ + P ++ + + + Y Y Sbjct: 148 EKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKEVQIMRRVKHPNIIQLLEFIQTPEYYY 207 Query: 134 YVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA-CELVYRDLKPENILIDR 192 VL GGE+F + ++ F E ++ QV A+ YLH C +V+RD+KPEN+L D Sbjct: 208 LVLELADGGELFHQIVRLTYFSEDLSRHVITQVAHAIRYLHEDCGVVHRDIKPENLLFDS 267 Query: 193 TGYI 196 ++ Sbjct: 268 IDFV 271 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 77.8 bits (183), Expect = 2e-15 Identities = 56/212 (26%), Positives = 106/212 (50%), Gaps = 15/212 (7%) Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKE---KIVRLKQIEHSYYEKKILC 112 + ++++ + +G G +G+V+ +H ++G+ AMK + E + V I K++ Sbjct: 1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVND 60 Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETS-----AKFYGAQVI 167 N V + LY V F+ ++ ++ ++ + TS + + Q++ Sbjct: 61 ENNRSNCVRLLDILHAESKLYLVFEFL-DMDLKKYMDRISETGATSLDPRLVQKFTYQLV 119 Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL----IRGRTWTLCGTPEYLAP 223 + + H+ +++RDLKP+N+LID+ G +K+ DFG + +R T + T Y AP Sbjct: 120 NGVNFCHSRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIV-TLWYRAP 178 Query: 224 EIIL-SKGYGMSVDWWSLGVLLFEMSAGHPPF 254 E++L S+ Y VD WS+G + EM P F Sbjct: 179 EVLLGSRHYSTGVDIWSVGCIFAEMIRRSPLF 210 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 77.4 bits (182), Expect = 3e-15 Identities = 52/207 (25%), Positives = 100/207 (48%), Gaps = 8/207 (3%) Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117 +++R + LG G + V+ ++ VTG+ A+K++ + + E ++ L P Sbjct: 2 NYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPST--AIREISLMKELRHP 59 Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGG--EMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175 ++ + + L V ++ + G + K + Q++ + + H Sbjct: 60 NIMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHE 119 Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCG---TPEYLAPEIIL-SKGY 231 +++RDLKP+N+LI+ G +K+ DFG + I T T Y AP+++L S+ Y Sbjct: 120 NRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVY 179 Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASD 258 S+D WS+G ++ EM+ G P F S+ Sbjct: 180 STSIDIWSVGCIMAEMATGRPLFAGSN 206 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 75.4 bits (177), Expect = 1e-14 Identities = 60/204 (29%), Positives = 97/204 (47%), Gaps = 11/204 (5%) Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL--CGLN- 115 +E LG G+FG V TGK A+K++ +K ++ + + +KI L+ Sbjct: 699 YEVVDFLGKGSFGQVLRCIDYETGKLVALKIIRNKKRFHMQALVETKILQKIREWDPLDE 758 Query: 116 FPFVVYMK-YYFKDNVYLYYVLPFIAGGEMFSHLRKMG--KFEETSAKFYGAQVILALEY 172 + V Y +YF+D++ V + G ++ ++ G K Q+I L Sbjct: 759 YCMVQYTDHFYFRDHLC---VATELLGKNLYELIKSNGFKGLPIVVIKSITRQLIQCLTL 815 Query: 173 LHACELVYRDLKPENILIDRT--GYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKG 230 L+ +++ DLKPENIL+ +K+ DFG +T + Y +PE+IL G Sbjct: 816 LNEKHVIHCDLKPENILLCHPFKSQVKVIDFGSSCFEGECVYTYIQSRFYRSPEVILGMG 875 Query: 231 YGMSVDWWSLGVLLFEMSAGHPPF 254 YG +D WSLG ++ EM G P F Sbjct: 876 YGTPIDVWSLGCIIAEMYTGFPLF 899 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 74.5 bits (175), Expect = 2e-14 Identities = 69/244 (28%), Positives = 113/244 (46%), Gaps = 19/244 (7%) Query: 65 LGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRL-KQIEHSYYEKKILCGLNFPFVV--Y 121 LG G G V LVKH + A K + +L KQI E +L P++V Y Sbjct: 72 LGEGNGGAVSLVKH--RNIFMARKTVYVGSDSKLQKQILR---ELGVLHHCRSPYIVGFY 126 Query: 122 MKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFE-ETSAKFYGAQVILALEYLHACELVY 180 + +K+N+ L + ++ G + + LR+ G + K + V + + +++ Sbjct: 127 GAFQYKNNISL--CMEYMDCGSLDAILREGGPIPLDILGKIINSMVKGLIYLYNVLHIIH 184 Query: 181 RDLKPENILIDRTGYIKITDFGFC-KLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWS 239 RDLKP N++++ G IK+ DFG +L+ T GT Y++PE I Y + D WS Sbjct: 185 RDLKPSNVVVNSRGEIKLCDFGVSGELVNSVAQTFVGTSTYMSPERIRGGKYTVKSDIWS 244 Query: 240 LGVLLFEMSAGHPPFFAS---DPMRIYEK----IVAGKYRCPSHFSVELKDIIGHVLQVD 292 LG+ + E++ P+ S D + I + + R PS F +L+ + L D Sbjct: 245 LGISIIELATQELPWSFSNIDDSIGILDLLHCIVQEEPPRLPSSFPEDLRLFVDACLHKD 304 Query: 293 TTRR 296 T R Sbjct: 305 PTLR 308 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 74.1 bits (174), Expect = 3e-14 Identities = 50/179 (27%), Positives = 91/179 (50%), Gaps = 11/179 (6%) Query: 126 FKDNVYLYYVLPFIAGGEMFS--HLRKMGKFE-ETSAKFYGAQVILALEYLHACELVYRD 182 +KD++ + VL + GG++ S H ET K + Q++LA+ Y+H +++RD Sbjct: 144 YKDSLCM--VLNYCPGGKLASVDHGISFDPMPLETCRKSF-RQLVLAVNYIHGKGVIHRD 200 Query: 183 LKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEII---LSKGYGMSVDW 237 +KP+NIL + + DFG + + G GTP ++APE+ L K G +D Sbjct: 201 IKPDNILFKENNNLCVIDFGLAEFLPKDGFVKPASGTPAFMAPELFDNELKKIKGKPLDI 260 Query: 238 WSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR 296 WS+GV L+ ++ PF S + + I P++ + +L+ ++ L+ + +R Sbjct: 261 WSMGVTLYVIAFAEFPFNGSTILDMINVIKGKSLMIPAYCNSDLRKLLERCLEKNPEKR 319 Score = 31.5 bits (68), Expect = 0.19 Identities = 16/63 (25%), Positives = 30/63 (47%) Query: 48 DKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYE 107 D+ + L + + +LG GA V+L + T YA+K +K + R ++ E Sbjct: 29 DEEDEGPLLKQYRLKNMLGYGACSTVYLAVDVSTNIEYAIKEFKKTSLRRREKFRLMQLE 88 Query: 108 KKI 110 K++ Sbjct: 89 KEL 91 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 72.5 bits (170), Expect = 9e-14 Identities = 53/162 (32%), Positives = 87/162 (53%), Gaps = 10/162 (6%) Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK--MLEKEKIVRLKQIEHSYYE 107 S+SN + +++ ++G+G+FG V+ ++ TG A+K L K +I R I+ E Sbjct: 1112 SKSNITIR-WQQGGLIGSGSFGTVYRAVNLDTGDLMAVKEVALHKPRISR-PMIKRIKGE 1169 Query: 108 KKILCGLNFPFVV--YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFE-ETSAKFYGA 164 +L + P VV Y ++ V ++ L G +F LR G+ E E + Y Sbjct: 1170 MLVLELFDHPNVVSYYGIEVHREKVNIFMEL--CQGSSLFEFLR-YGRIEDELVIQVYVL 1226 Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL 206 Q++ L Y+H+C + ++D+KPENIL D G +K TDFG K+ Sbjct: 1227 QLLEGLAYIHSCGVSHQDVKPENILFDHNGIMKFTDFGSAKM 1268 Score = 47.2 bits (107), Expect = 4e-06 Identities = 24/52 (46%), Positives = 36/52 (69%), Gaps = 4/52 (7%) Query: 206 LIRGRTWTLCGTPEYLAPEIIL---SKGYGMSVDWWSLGVLLFEMSAGHPPF 254 L + R ++L GTP Y+APE+IL S+ G ++D WSLG ++ EM+ G PP+ Sbjct: 1298 LDQNRGYSLTGTPTYMAPELILGNPSERVG-AMDIWSLGCVIVEMATGSPPW 1348 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 72.1 bits (169), Expect = 1e-13 Identities = 57/220 (25%), Positives = 101/220 (45%), Gaps = 25/220 (11%) Query: 58 DFERQKVLGTGAFGIVFLVKHIVTG-----------KYYAMKMLEKEKIVRLKQIEHSYY 106 +F+ K LG GA+GIV +++ + ++ +L K + +K + H Sbjct: 20 NFKVVKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHFRN 79 Query: 107 EKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQV 166 + I C + + Y F + VY+Y L ++ + ++ + + + Q+ Sbjct: 80 HRNITCIYDLDII--NPYNFNE-VYIYEEL---MEADLNAIIKSGQPLTDAHFQSFIYQI 133 Query: 167 ILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR-------GRTWTLCGTPE 219 + L+Y+H+ +++RDLKP N+L++ +KI DFG + G T Sbjct: 134 LCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRW 193 Query: 220 YLAPEIILS-KGYGMSVDWWSLGVLLFEMSAGHPPFFASD 258 Y APEI+LS Y +D WS+G +L E+ G P F D Sbjct: 194 YRAPEIMLSFSSYHKGIDVWSVGCILAELLGGTPLFKGKD 233 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 71.7 bits (168), Expect = 1e-13 Identities = 68/278 (24%), Positives = 119/278 (42%), Gaps = 25/278 (8%) Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109 S +++ + + LG G +G+V+ H TG A+K + + E Sbjct: 311 SSFRINMSEIIKLEELGKGNYGVVYKALHQPTGVTMALKEIRLS--LEEATFNQIIMELD 368 Query: 110 ILCGLNFPFVV--YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167 IL P++V Y ++ + +V++ + ++ G M L G +E V+ Sbjct: 369 ILHKAVSPYIVDFYGAFFVEGSVFI--CMEYMDAGSM-DKLYAGGIKDEGVLARTAYAVV 425 Query: 168 LALEYL-HACELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRTWTLCGTPEYLAPEI 225 L+ L +++RD+KP N+L++ G +K+ DFG L+ + T G Y+APE Sbjct: 426 QGLKTLKEEHNIIHRDVKPTNVLVNSNGQVKLCDFGVSGNLVASISKTNIGCQSYMAPER 485 Query: 226 ILSKG-------YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA----GKYRCP 274 I G Y + D WSLG+ + EM+ G P+ I+ ++ A P Sbjct: 486 IRVGGPTNGVLTYTVQADVWSLGLTILEMALGAYPYPPESYTSIFAQLSAICDGDPPSLP 545 Query: 275 SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKW 312 FS E +D + L + +L+ + NH W Sbjct: 546 DSFSPEARDFVNKCL-----NKNPSLRPDYHELANHPW 578 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 71.3 bits (167), Expect = 2e-13 Identities = 44/165 (26%), Positives = 87/165 (52%), Gaps = 5/165 (3%) Query: 64 VLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN-FPFVVYM 122 ++G GA+G+V+ + I G YA+K L K+ + KQ + E + ++ P+++ + Sbjct: 23 IIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNE-KQKKLQARELALHARVSSHPYIITL 81 Query: 123 KYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETS--AKFYGAQVILALEYLHACELVY 180 + +Y VL + G++F+++ + ++ S K Q+I A+E+ H+ + + Sbjct: 82 HRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLISAVEHCHSVGIYH 141 Query: 181 RDLKPENILI-DRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPE 224 RDLKPENI++ + + + DFG + CG+ Y++PE Sbjct: 142 RDLKPENIMVGNDVNTVYLADFGLATTEPYSSDFGCGSLFYMSPE 186 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 71.3 bits (167), Expect = 2e-13 Identities = 58/213 (27%), Positives = 95/213 (44%), Gaps = 6/213 (2%) Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118 +E+ +G G +G V+ + VTG A+K + E+ I + E KIL L Sbjct: 277 YEKIDQIGEGTYGKVYKAINTVTGDLVALKRIRLEQEKDGFPIT-TVREVKILQRLRHKN 335 Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178 +V + + +Y V ++ L F + K Q+ AL YLH + Sbjct: 336 IVRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHLSKQIFEALAYLHHRGV 395 Query: 179 VYRDLKPENILIDRTGYIKITDFGFCKL---IRGRTWT-LCGTPEYLAPEIILSK-GYGM 233 ++RD+K NIL++ G +K DFG + + +T T + PE++L + Y Sbjct: 396 LHRDIKGSNILLNNNGDLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDT 455 Query: 234 SVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKI 266 +VD WS G ++ E+ G P F D + E I Sbjct: 456 AVDIWSAGCIVMELFTGKPFFQGRDEISQLEVI 488 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 70.9 bits (166), Expect = 3e-13 Identities = 60/206 (29%), Positives = 94/206 (45%), Gaps = 7/206 (3%) Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKY-YAMKMLEKEKIVRLKQIEHSYYEK 108 S ++ L F +LG+G F VF V+ V YA+K L K K K+ E Sbjct: 557 SSTSHLLTRFRNVTLLGSGEFSEVFQVEDPVEKTLKYAVKKL-KVKFSGPKERNRLLQEV 615 Query: 109 KILCGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG---KFEETSAKFYGA 164 I L +V + ++ +LY + G + L + G + +E Sbjct: 616 SIQRALKGHDHIVELMDSWEHGGFLYMQVELCENGSLDRFLEEQGQLSRLDEFRVWKILV 675 Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR-GRTWTLCGTPEYLAP 223 +V L L+++H V+ DLKP N++I G +KI DFG + R G EY+AP Sbjct: 676 EVALGLQFIHHKNYVHLDLKPANVMITFEGTLKIGDFGMASVWPVPRGMEREGDCEYIAP 735 Query: 224 EIILSKGYGMSVDWWSLGVLLFEMSA 249 E++ + Y D +SLG+ +FE +A Sbjct: 736 EVLANHLYDKPADIFSLGITVFEAAA 761 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 70.5 bits (165), Expect = 3e-13 Identities = 56/216 (25%), Positives = 100/216 (46%), Gaps = 22/216 (10%) Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK--------EKIVRLKQIEHSYYEKK 109 ++E ++G GA+G+V H +G A+K + + +K + H +E Sbjct: 38 EYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNHPVFCLRTLREIKLLRHFRHENI 97 Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169 I P Y + ++VY+ L +++ +R + +++ Q++ A Sbjct: 98 ISILDILPPPSYQEL---EDVYIVQEL---METDLYRVIRSQ-PLSDDHCQYFTYQILRA 150 Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR------GRTWTLCGTPEYLAP 223 L+ +H+ +V+RDLKP N+L++ +K+ DFG + G T Y AP Sbjct: 151 LKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLARSTTAQGGNPGFMTEYVATRWYRAP 210 Query: 224 EIILS-KGYGMSVDWWSLGVLLFEMSAGHPPFFASD 258 EI+LS + Y ++D WS G +L EM + P F D Sbjct: 211 EIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKD 246 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 69.7 bits (163), Expect = 6e-13 Identities = 57/206 (27%), Positives = 102/206 (49%), Gaps = 9/206 (4%) Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115 ++D+E + + G++GIV+ T A+K ++ + I S E + L + Sbjct: 71 IDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPIT-SLREIESLSSIR 129 Query: 116 FPFVVYMKYYF--KDNVYLYYVLPFIAGGEMFSHLRKMGK-FEETSAKFYGAQVILALEY 172 +V ++ KD +Y V+ F+ ++ + L M + F ++ K Q++ A + Sbjct: 130 HDNIVELEKVVVGKDLKDVYLVMEFMEH-DLKTLLDNMPEDFLQSEVKTLMLQLLAATAF 188 Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIIL-S 228 +H ++RDLKP N+L++ TG IK+ DFG + + + L T Y APE++L + Sbjct: 189 MHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGA 248 Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPF 254 YG +D WS+G + EM P F Sbjct: 249 PSYGKEIDMWSIGCIFAEMITRTPLF 274 >SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizosaccharomyces pombe|chr 2|||Manual Length = 413 Score = 69.3 bits (162), Expect = 8e-13 Identities = 58/224 (25%), Positives = 104/224 (46%), Gaps = 28/224 (12%) Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112 N K+ E+++VL + F ++ + + K + EK R+K + K L Sbjct: 105 NTKITSTEQREVLLVKSNNKKFDTSIVLKHTHLSSKS-QNEKKARVKVFRQEIWALKTL- 162 Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYG---AQVILA 169 + P VV + Y+ + L V + GG+++ + +K + S +F G ++++ Sbjct: 163 --SHPCVVQLLNYYVSSAELILVENYCMGGDLYHYTKK--HHSDFSLEFVGRIFSELVHT 218 Query: 170 LEYLHACELVYRDLKPENILIDR---------------TGYIKITDFGFCKLIRGRTWTL 214 + YLH+ L++RDLK ENIL+ + I+I+DF + + + Sbjct: 219 VAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALIQISDFELSIFVDSKNHLV 278 Query: 215 ---CGTPEYLAPEIILSKGY-GMSVDWWSLGVLLFEMSAGHPPF 254 CG+ EY PE+ + + G D WSLG++LF + G PF Sbjct: 279 QSSCGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLEGRLPF 322 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 65.7 bits (153), Expect = 1e-11 Identities = 36/97 (37%), Positives = 50/97 (51%), Gaps = 2/97 (2%) Query: 160 KFYGAQVILALEYLHACELVYRDLKPENILIDRT--GYIKITDFGFCKLIRGRTWTLCGT 217 K + Q + AL L +++ DLKPEN+L+ IK+ DFG + +T + Sbjct: 622 KSFALQGLQALRLLQGQNIIHCDLKPENLLLSHPLKARIKLIDFGSSCFYNEKVYTYLQS 681 Query: 218 PEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF 254 Y APEIIL YG +D WS G +L E+ G P F Sbjct: 682 RFYRAPEIILGLEYGKEIDIWSFGCILAELFTGVPLF 718 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 64.5 bits (150), Expect = 2e-11 Identities = 60/226 (26%), Positives = 107/226 (47%), Gaps = 23/226 (10%) Query: 49 KSESNAKLND-----FERQ----KVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLK 99 KS+S+A L D F++ ++LG+GA G V ++K GK +A+K + + Sbjct: 283 KSKSSANLQDDHFGLFKKYGKFGRMLGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETE 342 Query: 100 QIEHSYYEKKILC---GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEE 156 + E++ C L+ ++ ++N Y V+ + A +MFS + GK Sbjct: 343 R-EYARKVTAEFCIGSALHHTNIIETLDIVEENKKFYEVMEY-APYDMFSIVMS-GKMTM 399 Query: 157 TSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR-------G 209 Q++ + YLH+ L +RDLK +N+++D ++KI DFG + + Sbjct: 400 PEVYCCFKQLLSGVAYLHSMGLAHRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIV 459 Query: 210 RTWTLCGTPEYLAPEIILSKGYG-MSVDWWSLGVLLFEMSAGHPPF 254 + G+ YLAPE ++ K Y +VD WS ++ M+ P+ Sbjct: 460 EATGVVGSDPYLAPETLVRKLYDPRAVDIWSSAIIFCCMALRRFPW 505 Score = 26.6 bits (56), Expect = 5.5 Identities = 12/47 (25%), Positives = 24/47 (51%) Query: 251 HPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRY 297 H P +D +++ + G +R E + +I H+L++D +RY Sbjct: 557 HSPNSKTDNSSTHKQELYGPWRLLRLLPRETRAVIAHMLELDPVKRY 603 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 64.5 bits (150), Expect = 2e-11 Identities = 52/199 (26%), Positives = 89/199 (44%), Gaps = 8/199 (4%) Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQ-IEHSYY-EKKILCGLNF 116 + +++ +G G + +VFL + T + A+K K K+ + K I+ S E K L Sbjct: 11 YVKERKVGEGTYAVVFLGRQKETNRRVAIK---KIKVGQFKDGIDISALREIKFLRESRH 67 Query: 117 PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHAC 176 V+ + F L +L F+ K F+ K + ++ L ++H+ Sbjct: 68 DNVIELVDVFSTKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSR 127 Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS-KGYGM 233 +++RDLKP N+LI G +K+ DFG + T Y PE+ + + YG Sbjct: 128 FILHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSHMSHQVITRWYRPPELFMGCRSYGT 187 Query: 234 SVDWWSLGVLLFEMSAGHP 252 VD WS+G + E+ P Sbjct: 188 GVDMWSVGCIFAELMLRTP 206 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 64.1 bits (149), Expect = 3e-11 Identities = 63/237 (26%), Positives = 108/237 (45%), Gaps = 24/237 (10%) Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG-LN 115 N + + +G+G+FG ++L ++V+G+ A+K LE + + Q+E+ Y +IL G + Sbjct: 9 NKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIK-LESTR-AKHPQLEYEYRVYRILSGGVG 66 Query: 116 FPFVVYMKYYFKDNVYLYYVL-PFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174 PFV + N + +L P + ++F+ + KF + Q+I +E++H Sbjct: 67 IPFVRWFGVECDYNAMVMDLLGPSLE--DLFNFCNR--KFSLKTVLLLADQLISRIEFIH 122 Query: 175 ACELVYRDLKPENILI---DRTGYIKITDFGFCKLIRG----------RTWTLCGTPEYL 221 + ++RD+KP+N L+ R + I DFG K R L GT Y Sbjct: 123 SKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTARYA 182 Query: 222 APEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAGKYRCPS 275 + L D SLG +L G P+ A+ + YEKI+ K P+ Sbjct: 183 SINTHLGIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIMEKKISTPT 239 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 63.3 bits (147), Expect = 5e-11 Identities = 39/110 (35%), Positives = 60/110 (54%), Gaps = 8/110 (7%) Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPE----- 219 Q+I + YLH +++RDLKP NI+I TG +KI D G +LIR + Sbjct: 123 QIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLIRDPILPFYSSDRVVVTI 182 Query: 220 -YLAPEIIL-SKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIV 267 Y APE++L + Y ++D W++G + EM A P F D +++ +K V Sbjct: 183 WYRAPELLLGAHDYTPAIDVWAIGCIYGEMLA-LSPLFKGDEIKMEDKKV 231 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 63.3 bits (147), Expect = 5e-11 Identities = 37/113 (32%), Positives = 59/113 (52%), Gaps = 12/113 (10%) Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL----------IRGRTWTL 214 Q++ L Y+H+ + +RD+KPENILI G ++ITDFG C + + ++ + Sbjct: 567 QILRGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGACDVLCNPGDDITAVESKSMGI 626 Query: 215 CGTPEYLAPEIILSKGY-GMSVDWWSLGVLLFEMSAGHPPF-FASDPMRIYEK 265 G+ Y+APEI+ Y D WS ++L + PF AS ++Y K Sbjct: 627 FGSDPYMAPEILTPGSYNAFFADMWSTAIVLHCLYFRTYPFRKASQNDQLYAK 679 >SPAC823.03 |ppk15||serine/threonine protein kinase Ppk15 |Schizosaccharomyces pombe|chr 1|||Manual Length = 534 Score = 62.9 bits (146), Expect = 7e-11 Identities = 51/200 (25%), Positives = 94/200 (47%), Gaps = 14/200 (7%) Query: 65 LGTGAFGIVFLVKHIVTGKYYAMKMLEKEKI--------VRLKQIEHSYYEKKILCGLNF 116 LG G FG V + + T + A+K+++ + V + ++ ++ Y+ + L Sbjct: 136 LGHGTFGQVARCQDLKTQQIVAIKVIKNKPAFYNQCVMEVSILELLNNKYDPEDKRHL-- 193 Query: 117 PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHAC 176 +Y ++ K+++ L + L I E+ + G + + + Q++ L Sbjct: 194 -IRLYDQFMHKNHLCLVFELLSINLYELIKQNQFRG-LHLSLVRSFATQLLSCTSLLKQA 251 Query: 177 ELVYRDLKPENILID--RTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMS 234 +++ DLKPENIL+ + +K+ DFG R +T + Y +PE+IL Y Sbjct: 252 RIIHCDLKPENILLQDLSSPIVKVIDFGSACHERQTVYTYIQSRFYRSPEVILGLHYNCG 311 Query: 235 VDWWSLGVLLFEMSAGHPPF 254 +D WSLG +L E+ G P F Sbjct: 312 IDMWSLGCILAELFLGLPLF 331 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 62.5 bits (145), Expect = 9e-11 Identities = 52/224 (23%), Positives = 98/224 (43%), Gaps = 12/224 (5%) Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG--LNFPFV 119 Q LG G F V + +A+K++ +++ + ++ +++ + Sbjct: 162 QSNLGKGMFSTVVSALDRNRNQTFAIKIIRNNEVMYKEGLKEVSILERLQAADREGKQHI 221 Query: 120 VYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAK---FYGAQVILALEYLHAC 176 ++ + +F +L V ++ + L+K G+ S K Y Q+ +AL+ L C Sbjct: 222 IHYERHFMHKNHLCMVFEMLSLN-LRDILKKFGRNVGLSIKAVRLYAYQMFMALDLLKQC 280 Query: 177 ELVYRDLKPENILI-DRTGYIKITDFGFCK-LIRGRTWTLCGTPEYLAPEIILSKGYGMS 234 +++ D+KP+N+L+ ++ +KI D G + Y APEIIL Y Sbjct: 281 NVIHSDIKPDNMLVNEKRNILKICDLGSASDASENEITPYLVSRFYRAPEIILGFPYSCP 340 Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFS 278 +D WS+G L+E+ G F P R +++ C FS Sbjct: 341 IDTWSVGCSLYELYTGQILF----PGRTNNQMLRYMMECKGKFS 380 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 60.1 bits (139), Expect = 5e-10 Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 18/211 (8%) Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN----F 116 +QK LG G+FG V+L + Y ++K K + +H + + L Sbjct: 24 KQK-LGDGSFGTVYLAQRKEKNGLYETVAVKKLKNSSKPKPKHELLKLRESLALRKISKH 82 Query: 117 PFVVYMKYYFKDNVY-LYYVLPFIAGGEMFSHLRKMGK-FEETSAKFYGAQVILALEYLH 174 P ++ + F D ++ V+ F+ R+ G+ F + +A Q+I +E++H Sbjct: 83 PCLIDLLETFMDPYRNIFLVMEFMDCNLFQLFKRRQGRLFTKETAFNILLQIISGIEHIH 142 Query: 175 ACELVYRDLKPENILIDRTG--------YIKITDFGFCK--LIRGRTWTLCGTPEYLAPE 224 ++RD+KPENIL+ R IK+ DFG + + T Y APE Sbjct: 143 KHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLARPSVSSDPLTEYVSTRWYRAPE 202 Query: 225 IILSKG-YGMSVDWWSLGVLLFEMSAGHPPF 254 ++L G Y SVD ++ G ++FE+ + P F Sbjct: 203 LLLRSGSYNHSVDLYAFGCIVFEIYSLKPLF 233 >SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosaccharomyces pombe|chr 1|||Manual Length = 439 Score = 58.8 bits (136), Expect = 1e-09 Identities = 61/245 (24%), Positives = 105/245 (42%), Gaps = 26/245 (10%) Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109 S SN + K +G G+FG++F +++ + A+K ++ V Q+ Y K Sbjct: 6 SHSNVVGVHYRVGKKIGEGSFGMLFQGVNLINNQPIALKFESRKSEV--PQLRDEYLTYK 63 Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGG--EMFSHLRKMGKFEETSAKFYGAQVI 167 +L GL P + + YY ++ +Y V+ + ++F + + +F + Q+I Sbjct: 64 LLMGL--PGIPSVYYYGQEGMYNLLVMDLLGPSLEDLFDYCGR--RFSPKTVAMIAKQMI 119 Query: 168 LALEYLHACELVYRDLKPENILIDRTG-----YIKITDFGFCKLIRG------RTW---- 212 ++ +H +YRD+KP+N LI G I DFG K R R + Sbjct: 120 TRIQSVHERHFIYRDIKPDNFLIGFPGSKTENVIYAVDFGMAKQYRDPKTHVHRPYNEHK 179 Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAG 269 +L GT Y++ L + D S+G + G P+ A+ + YEKI Sbjct: 180 SLSGTARYMSINTHLGREQSRRDDLESMGHVFMYFLRGSLPWQGLKAATNKQKYEKIGEK 239 Query: 270 KYRCP 274 K P Sbjct: 240 KQVTP 244 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 57.2 bits (132), Expect = 3e-09 Identities = 53/214 (24%), Positives = 95/214 (44%), Gaps = 22/214 (10%) Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKY-----YAMKMLEKEKIVRLKQIEHSYYEKKILCG 113 ++ ++ L G++G V L + YA+K ++K L+++ + L Sbjct: 9 YKVERPLNKGSYGTVVLAHRLFRTPRCKDLKYAIKCIKKPAYTFLQEVNIL----RQLSR 64 Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM----GKFEETSAKFYGAQVILA 169 +++ F+DNVY Y VL + G+++ + K + K Q+I Sbjct: 65 SRHRNIIHFVESFEDNVYYYVVLEYCPLGDLYECILNNDFPNAKNQPEMIKNIFLQIIDG 124 Query: 170 LEYLHACELVYRDLKPENILIDRTG-----YIKITDFGFCKLIRGRTWTLCGTPEYLAP- 223 + +LH+ + +RDLKPEN L+ + +KI+DFG + G+ Y+AP Sbjct: 125 VAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLACRDKISYDFGTGSDRYMAPE 184 Query: 224 --EIILSKGYG-MSVDWWSLGVLLFEMSAGHPPF 254 E + GY + D W+LG+ L + PF Sbjct: 185 QFEEVDGAGYSPRAADIWALGICLLNLIFARNPF 218 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 57.2 bits (132), Expect = 3e-09 Identities = 58/209 (27%), Positives = 89/209 (42%), Gaps = 20/209 (9%) Query: 65 LGTGAFGIVFLV------KHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118 +G G FG V+L K +V K K+ + RL+++ HS + N Sbjct: 42 VGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREV-HSL----LRLSENENI 96 Query: 119 VVYMKYYFKDNVYLYYVLPFI-AGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177 V Y L+ V+ F+ RK + Q+ L ++H Sbjct: 97 VNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHTNG 156 Query: 178 LVYRDLKPENILI----DRTGY-IKITDFGFCKLIRGR-TWT-LCGTPEYLAPEIILSKG 230 +RD+KPENILI D + + +KI DFG + I R +T T Y APE++L Sbjct: 157 FFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPELLLRDS 216 Query: 231 -YGMSVDWWSLGVLLFEMSAGHPPFFASD 258 Y VD ++ G + FE++ P F +D Sbjct: 217 YYSFPVDIYAAGCMAFEIATLQPIFPGND 245 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 56.8 bits (131), Expect = 5e-09 Identities = 50/156 (32%), Positives = 75/156 (48%), Gaps = 27/156 (17%) Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK-----LIRGRTW------- 212 Q++ AL Y+H+ +++RDLKP NI +D +K+ DFG W Sbjct: 755 QILEALAYIHSRGMMHRDLKPGNIFLDENRNVKLGDFGLATENENYQDNNDKWKNRQSAD 814 Query: 213 ----TLCGTPEYLAPEIILSKG---YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK 265 T GT Y+APE++ + Y VD +SLG++LFEM + + +RI + Sbjct: 815 EDLTTGVGTALYVAPELLSRRNGVRYDAKVDMYSLGIILFEMCMTFST--SMERIRIIDT 872 Query: 266 IVAGKYRCPSHF-----SVELKDIIGHVLQVDTTRR 296 I + PS F S E K +I +LQ D T+R Sbjct: 873 IRSPSISFPSTFPFSRASHEFK-VIHCLLQHDPTKR 907 Score = 36.3 bits (80), Expect = 0.007 Identities = 16/33 (48%), Positives = 22/33 (66%) Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKML 90 DFE + LG G FG V VK+ + G++YA+K L Sbjct: 555 DFEELEFLGRGGFGEVVKVKNRIDGRFYAVKKL 587 Score = 31.9 bits (69), Expect = 0.15 Identities = 17/80 (21%), Positives = 40/80 (50%), Gaps = 3/80 (3%) Query: 132 LYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILID 191 LY + + +FS L+ + + + + + ++ L LH + ++ L +N+++ Sbjct: 324 LYVLQEYSPKFTLFSLLQTVLTLDVETVRAFSNNILEGLAELHRLGISHKSLHLDNVVLF 383 Query: 192 RTG---YIKITDFGFCKLIR 208 +G + K+ DFGF + +R Sbjct: 384 HSGHRTFAKLMDFGFTRTLR 403 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 56.4 bits (130), Expect = 6e-09 Identities = 42/156 (26%), Positives = 80/156 (51%), Gaps = 11/156 (7%) Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG-LN 115 N + + +G+G+FG ++L + V G+ A+K LE K R Q+E+ + IL G + Sbjct: 10 NKYRIGRKIGSGSFGQIYLGLNTVNGEQVAVK-LEPLK-ARHHQLEYEFRVYNILKGNIG 67 Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGG--EMFSHLRKMGKFEETSAKFYGAQVILALEYL 173 P + +++ N Y V+ + ++F + + KF + Q+I +EY+ Sbjct: 68 IPTI---RWFGVTNSYNAMVMDLLGPSLEDLFCYCGR--KFTLKTVLLLADQLISRIEYV 122 Query: 174 HACELVYRDLKPENILIDR-TGYIKITDFGFCKLIR 208 H+ ++RD+KP+N L+ + + + + DFG K R Sbjct: 123 HSKSFLHRDIKPDNFLMKKHSNVVTMIDFGLAKKYR 158 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 54.4 bits (125), Expect = 2e-08 Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 17/111 (15%) Query: 160 KFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTL----- 214 + Y Q++ A++ +H +V+ DLKP N L+ G +K+ DFG K I T + Sbjct: 420 RMYWEQMLEAVQVVHDQNIVHSDLKPANFLLVE-GNLKLIDFGIAKAIGNDTTNIHRDSH 478 Query: 215 CGTPEYLAPEIILSKG-----------YGMSVDWWSLGVLLFEMSAGHPPF 254 GT Y+APE + G D WSLG +L++M G PF Sbjct: 479 IGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPF 529 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 54.4 bits (125), Expect = 2e-08 Identities = 62/230 (26%), Positives = 97/230 (42%), Gaps = 33/230 (14%) Query: 53 NAKL-NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111 N+K N + ++LG G FG V TG++ A+K+ R E S E ++L Sbjct: 355 NSKFANRYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPKYR----EASLIELRVL 410 Query: 112 CGL------NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG--KFEETSAKFYG 163 + N + ++ YF ++ V G +F L+ F + Sbjct: 411 QTIAHSDPTNENKCIQLRDYFDYRKHICIVTDLF-GWSVFDFLKNNNYIPFPLKHIQMLS 469 Query: 164 AQVILALEYLHACELVYRDLKPENILI----DRT------GY---------IKITDFGFC 204 Q+ ++ +LH+ LV+ DLKPEN+L+ RT Y I++ DFG Sbjct: 470 QQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSA 529 Query: 205 KLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF 254 ++ T Y APEIIL G+ D WS+G +L E+ G F Sbjct: 530 TFEDEYHSSVVSTRHYRAPEIILGLGWSYPCDVWSIGCILVELFTGQALF 579 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 52.8 bits (121), Expect = 7e-08 Identities = 40/150 (26%), Positives = 69/150 (46%), Gaps = 11/150 (7%) Query: 65 LGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKY 124 +G G+FG++F +++ + A+K + Q+ Y K+L G VY Y Sbjct: 18 IGEGSFGVIFEGTNLLNNQQVAIKFEPRRSDA--PQLRDEYRTYKLLAGCTGIPNVY--Y 73 Query: 125 YFKDNVYLYYVLPFIAGGEMFSHLRKMG-KFEETSAKFYGAQVILALEYLHACELVYRDL 183 + ++ ++ V+ + G + L G KF + Q++ ++ +H LVYRD+ Sbjct: 74 FGQEGLHNILVIDLL-GPSLEDLLDLCGRKFSVKTVAMAAKQMLARVQSIHEKSLVYRDI 132 Query: 184 KPENILIDR-----TGYIKITDFGFCKLIR 208 KP+N LI R I + DFG K R Sbjct: 133 KPDNFLIGRPNSKNANMIYVVDFGMVKFYR 162 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 50.8 bits (116), Expect = 3e-07 Identities = 26/100 (26%), Positives = 55/100 (55%), Gaps = 4/100 (4%) Query: 160 KFYGAQVILALEYLHACELVYRDLKPENILID-RTGYIKITDFGFCKLIR-GRTWTLCGT 217 ++Y +++ AL++ H+ +++RD+KP N++ID + +++ D+G + G + + Sbjct: 138 RYYSYELLKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGMEYNVRVA 197 Query: 218 PEYL-APEIILS-KGYGMSVDWWSLGVLLFEMSAGHPPFF 255 Y PE+++ + Y S+D WS GV+ + FF Sbjct: 198 SRYFKGPELLVDFREYDYSLDIWSFGVMFAALIFKKDTFF 237 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 50.8 bits (116), Expect = 3e-07 Identities = 55/222 (24%), Positives = 93/222 (41%), Gaps = 26/222 (11%) Query: 65 LGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG-LNFPFVVYMK 123 +G G+FG++F +++ + A+K K+ Q+ Y K+L G P V Y Sbjct: 18 IGEGSFGVIFDGMNLLNNQLIAIKFEPKKS--EAPQLRDEYRTYKLLVGNAGIPNVYYFG 75 Query: 124 YYFKDNVYLYYVL-PFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRD 182 N+ + +L P + ++F + +F + Q++ ++ +H LVYRD Sbjct: 76 QEGLHNILVIDLLGPSLE--DLFEWCGR--RFSVKTVAMTAKQMLSRVQTIHEKNLVYRD 131 Query: 183 LKPENILIDR-----TGYIKITDFGFCKLIR----------GRTWTLCGTPEYLAPEIIL 227 +KP+N LI R + + DFG K R +L GT Y++ L Sbjct: 132 IKPDNFLIGRPSSRNANMVYMVDFGMAKYYRDPKTKQHIPYSERKSLSGTARYMSINTHL 191 Query: 228 SKGYGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKI 266 + D SLG + G P+ A++ YEKI Sbjct: 192 GREQSRRDDLESLGHVFMYFLRGSLPWQGLKAANNKHKYEKI 233 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 48.4 bits (110), Expect = 2e-06 Identities = 75/303 (24%), Positives = 124/303 (40%), Gaps = 32/303 (10%) Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVY 121 Q+ L G F V+L + K + +K + L+ + K L G V Y Sbjct: 60 QRYLSEGGFSHVYLAL-LENEKPFVLKRIYVPDKTALQLVHGEIETMKRLKGHRH-IVNY 117 Query: 122 MK----YYFKDNVY-LYYVLPFIAGGEM--FSHLRKMGKFEETSAKFYGAQVILALEYLH 174 + Y +N Y +Y ++ F AGG + F + R + E A V A+ +H Sbjct: 118 IDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHRLTEGEILKILADVCDAVAAMH 177 Query: 175 ACE--LVYRDLKPENILIDRTGYIKITDFG-FCKLIRGRTW-----------TLCGTPEY 220 + L++RDLK EN+L+ K+ DFG C+ + T TP+Y Sbjct: 178 YLDPPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAPATTPDTIMFLEQNIAAYTTPQY 237 Query: 221 LAPEII---LSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHF 277 APE+I +G D W++GVL +++ PF I + + + + Sbjct: 238 RAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPFEQVGNSAILK--ASFSFPPFPRY 295 Query: 278 SVELKDIIGHVLQVDTTRR---YGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKI 334 S +K I LQ + R Y TLK+ +++ + + + S +PP P Sbjct: 296 SDRMKRFIATCLQEQPSHRPNIYQTLKE-IMEMQGTPLKLPDVYGGVNASTYNPPRAPLQ 354 Query: 335 RSP 337 R+P Sbjct: 355 RTP 357 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 48.0 bits (109), Expect = 2e-06 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 8/87 (9%) Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG--FCKLIRGRTWTL-----CGT 217 Q++ + Y+H+ + +RD+K +NI++D +KI DFG F + TL G+ Sbjct: 347 QLLDGVAYMHSLGIAHRDIKLDNIMLDENLNVKIIDFGTAFVFHYPFESTTLMSDGVVGS 406 Query: 218 PEYLAPEIILSKGYGMS-VDWWSLGVL 243 Y+APE++ K Y S VD WS ++ Sbjct: 407 KPYVAPEVLTQKPYDPSAVDVWSCAIV 433 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 46.4 bits (105), Expect = 6e-06 Identities = 54/218 (24%), Positives = 92/218 (42%), Gaps = 25/218 (11%) Query: 62 QKVLGTGAFGIVFLVKHIVTGK---YYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118 ++ L G F V+LV+ + GK +K + + L+ + K++ Sbjct: 36 KRYLAEGGFSHVYLVQLVFPGKPPFEAVLKRIFATDAMALRAVHEEVRTMKLVSNQKRCV 95 Query: 119 VVYMKYYFKDNVYLYYVLPFI----AGGEM-FSHLRKMGKFEETSAKFYGAQVILALEYL 173 Y +F+ + + VL + GG + F + R + E + V A+ + Sbjct: 96 SYYGSEFFRTSKNQFEVLVLLEYCPCGGLIDFLNTRLQVRLSEQEILKIASDVTEAVAVM 155 Query: 174 HACE--LVYRDLKPENILIDRTGYIKITDFG-FCKLIRGRTWTL-----------CGTPE 219 H + L++RDLK EN+L+ K+ DFG C I G T + Sbjct: 156 HYLKPPLIHRDLKIENVLLAAPNSYKLCDFGSACHPIPGAKTAAEAKQLEYDIEKFTTWQ 215 Query: 220 YLAPEII-LSKGYGM--SVDWWSLGVLLFEMSAGHPPF 254 Y PE+I + KG+G+ D W+LGVL +++ PF Sbjct: 216 YRCPEMINVHKGFGIDEKSDIWALGVLFYKLCYYTTPF 253 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 43.2 bits (97), Expect = 6e-05 Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 8/98 (8%) Query: 165 QVILALEYLHACELVYRDLKPENILID-RTGYIKITDF--GFCKLIRG----RTWTLCGT 217 Q+ ALEYL +++RD+ P NIL+D G ++DF + K G GT Sbjct: 112 QISSALEYLEKHGILHRDIHPNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQELIPQIGT 171 Query: 218 PEYLAPEIILS-KGYGMSVDWWSLGVLLFEMSAGHPPF 254 Y A E + YG VD W+ G+L+ E+ + F Sbjct: 172 GHYRAIETLFGCHSYGHEVDRWTFGILIAELFSNQALF 209 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 42.3 bits (95), Expect = 1e-04 Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 23/143 (16%) Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFC----------KLIRG--RTW 212 Q + +L YL L++RDLK EN+L+ + K+ DFG I+ ++ Sbjct: 147 QGVASLHYLRP-PLIHRDLKVENVLLSFNTF-KLCDFGSVTEPMHAAENSSEIQALEKSI 204 Query: 213 TLCGTPEYLAPEII-LSKGYGMSV--DWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG 269 T +Y APE+I L G G+ D W+LGVLL+++ PF P I+ Sbjct: 205 NTFTTYQYRAPEMINLYSGLGIDEKSDMWALGVLLYKLCYYTTPFETQGP----NAILTA 260 Query: 270 KYRCPSH--FSVELKDIIGHVLQ 290 Y P +S LK++I +LQ Sbjct: 261 SYSFPPFPPYSHSLKNVIIALLQ 283 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 41.9 bits (94), Expect = 1e-04 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 7/86 (8%) Query: 37 KLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIV 96 + R +ESW +S ++ + DFE +LG G FG V+ V++ + G YAMK + Sbjct: 150 RFRDLTLESWL-QSRNSRYIEDFEEYSLLGRGGFGSVYHVRNKIDGAEYAMKKINS---- 204 Query: 97 RLKQIEHS--YYEKKILCGLNFPFVV 120 +Q+ +S + E K L ++ P V+ Sbjct: 205 TFQQMSYSKIFREIKCLAKMDHPNVI 230 Score = 25.8 bits (54), Expect = 9.7 Identities = 10/29 (34%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Query: 166 VILALEYLH-ACELVYRDLKPENILIDRT 193 +I + Y+H L++RD+KP NI + ++ Sbjct: 400 IINGVMYVHEGVNLIHRDIKPSNIFLAKS 428 >SPBC530.14c |dsk1||SR protein-specific kinase Dsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 544 Score = 38.7 bits (86), Expect = 0.001 Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 12/140 (8%) Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG----LNFP 117 ++ LG G F V+L + A+K++ + R I+ +KI G L Sbjct: 84 ERKLGWGHFSTVWLAYDRAAKRRVALKVVRSAEHYRETSIDEIRILQKIREGDEKHLGKK 143 Query: 118 FVVYMKYYF----KDNVYLYYVLPFIAGGEMFSHLRKMGK--FEETSAKFYGAQVILALE 171 ++ + YF + ++ V + G + S ++ G K Q+++AL+ Sbjct: 144 HIISLLDYFVHRGPNGAHVCMVFE-VLGENLLSLIQSYGHRGVPVGIVKQIAYQLLIALD 202 Query: 172 YLHA-CELVYRDLKPENILI 190 YLH C +++ DLKPEN+LI Sbjct: 203 YLHRECGIIHTDLKPENVLI 222 Score = 38.7 bits (86), Expect = 0.001 Identities = 19/55 (34%), Positives = 27/55 (49%) Query: 196 IKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAG 250 +KI D G R T +Y +PE+IL +G S D WS ++FE+ G Sbjct: 356 VKIADLGNACWTRKHFTNDVQTRQYRSPEVILGCRWGASADCWSFACIIFELLTG 410 >SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizosaccharomyces pombe|chr 1|||Manual Length = 344 Score = 37.9 bits (84), Expect = 0.002 Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 13/123 (10%) Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLE---KEKIVRLKQIEHSYYEKKILCGLNFPF 118 QK+LG G F V+LV+++ K YA+K ++ K ++ K ++ + Y +K N+ Sbjct: 35 QKLLGEGGFAFVYLVQNVSNEKLYALKKIKCSFGNKGIK-KAMKEADYHRKFKS--NYLL 91 Query: 119 VVYMKYYFKD---NVYLYYVLPFIAGGEMFSHLRKM---GKF-EETSAKFYGAQVILALE 171 Y K+ + ++Y + P+ A G + +R G + E + + + AL+ Sbjct: 92 KSYTHQLVKEADGSEFVYILFPYFAKGSVAQVIRNCDIEGSYISEKRILVWCSCLCKALQ 151 Query: 172 YLH 174 YLH Sbjct: 152 YLH 154 >SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 665 Score = 37.5 bits (83), Expect = 0.003 Identities = 52/223 (23%), Positives = 88/223 (39%), Gaps = 13/223 (5%) Query: 82 GKYYAMKMLEKEKIV----RLKQIEHSYY---EKKILCGLNFPFVVYMKYYFKDNVYLYY 134 G Y A + L+KE +V + + H E + L GL+ ++ F ++ Sbjct: 401 GTYVARQTLDKEVVVIKRFDISAVTHRRLLLEELQRLSGLSHKNLIRYNESFWYLNNIWS 460 Query: 135 VLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTG 194 V + S L F E + ++ L +LH + + +L E I + ++ Sbjct: 461 VFEYKDPSTKLSALIPKYFFSELNIASICYEISSGLAFLHNSGIAHHNLTTECIYLTKSS 520 Query: 195 YIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGY--GMSVDWWSLGVLLFEMSAGHP 252 +KI ++ F R T G ++ P+ ++ K Y G D SLG++ E+ G P Sbjct: 521 CLKIGNYAFSSPYIERQ-TNRGAVSHV-PDWLIEKNYKEGFMKDVKSLGLVALEIFQGQP 578 Query: 253 PFFASDPMRIYEKIVAGKY--RCPSHFSVELKDIIGHVLQVDT 293 FF I A R S E K+ + LQ +T Sbjct: 579 NFFRKSIQSIQLTPNANVLVNRVRGLISQEFKEFLLQTLQAET 621 >SPBP23A10.10 |ppk32||serine/threonine protein kinase Ppk32 |Schizosaccharomyces pombe|chr 2|||Manual Length = 749 Score = 36.7 bits (81), Expect = 0.005 Identities = 35/151 (23%), Positives = 69/151 (45%), Gaps = 20/151 (13%) Query: 165 QVILALEYLH-ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTL----CGTP- 218 Q+I L +LH + ++++ +++P ++++D G K+ F F + + + G P Sbjct: 156 QIIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDWKLCGFSFSQSVESARYEFNDYDFGIPS 215 Query: 219 ------EYLAPEIILSKGYGMSVDWWSLGVLLFEM-SAGHPPFFASDPMRIYEKIVAGKY 271 ++LAPE I + G D +S G L++ + + A++ + YEK + Sbjct: 216 SLQQSMDFLAPEYITHEIAGPESDVFSFGCLIYSIFNKNQSIINANNHLLSYEKEIT-SL 274 Query: 272 RCPSHF------SVELKDIIGHVLQVDTTRR 296 P+ S LK ++ L VD +R Sbjct: 275 NSPTFIESKNLPSENLKSLLKETLAVDPKQR 305 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 35.9 bits (79), Expect = 0.009 Identities = 13/26 (50%), Positives = 21/26 (80%) Query: 165 QVILALEYLHACELVYRDLKPENILI 190 Q+ + +LH+ +LV+RDLKP+NIL+ Sbjct: 757 QIAFGVSHLHSLDLVHRDLKPQNILL 782 >SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 34.3 bits (75), Expect = 0.028 Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116 +DFE ++LG G +G V+ ++ G YA+K + ++ + + E + L LN Sbjct: 222 SDFEELELLGKGGYGSVYKARNKFDGVEYALKKIPL-RLRSFSTSSNIFRESRTLARLNH 280 Query: 117 PFVV 120 P V+ Sbjct: 281 PNVI 284 Score = 30.3 bits (65), Expect = 0.45 Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 1/28 (3%) Query: 164 AQVILALEYLH-ACELVYRDLKPENILI 190 A+++ + YLH A LV+RDLKP NI + Sbjct: 472 ARILEGVLYLHDAMHLVHRDLKPRNIFL 499 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 33.1 bits (72), Expect = 0.064 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Query: 154 FEETSAKFYGAQVILALEYLHACELVYRDLKPENILID-RTGYIKITDFGFCKLIRGR 210 F Y + A++ +++RD+KP N L D RT + + DFG + GR Sbjct: 188 FSYRDMSIYFRCLFQAMQQTQTLGIIHRDIKPSNFLFDVRTKHGVLVDFGLAERYDGR 245 Score = 27.9 bits (59), Expect = 2.4 Identities = 15/43 (34%), Positives = 19/43 (44%), Gaps = 1/43 (2%) Query: 216 GTPEYLAPEIILS-KGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257 GT + APE++ VD WS GV+L P F S Sbjct: 290 GTRGFRAPEVLFKCSSQSPKVDIWSAGVILLSFLTKRFPMFNS 332 >SPBC336.14c |ppk26||serine/threonine protein kinase Ppk26|Schizosaccharomyces pombe|chr 2|||Manual Length = 589 Score = 32.7 bits (71), Expect = 0.084 Identities = 18/52 (34%), Positives = 25/52 (48%) Query: 148 LRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKIT 199 L + K E Y Q+ +AL YLH L P IL+D+T I+I+ Sbjct: 324 LEENRKIPERELWNYFFQLTIALSYLHKSGFACNKLTPSRILVDQTERIRIS 375 >SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizosaccharomyces pombe|chr 2|||Manual Length = 1706 Score = 31.1 bits (67), Expect = 0.26 Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Query: 133 YYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDR 192 Y V P++ ++ + E T K+ Q++ + H + + D+K ENILI Sbjct: 98 YLVRPYVTHN-LYDRISTRPFLELTEKKWIMFQLLKGISDCHRLGVCHGDIKSENILITS 156 Query: 193 TGYIKITDFGFCK 205 + ++DF K Sbjct: 157 WNWAYLSDFSSFK 169 >SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosaccharomyces pombe|chr 2|||Manual Length = 429 Score = 29.9 bits (64), Expect = 0.59 Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 1/41 (2%) Query: 216 GTPEYLAPEIILS-KGYGMSVDWWSLGVLLFEMSAGHPPFF 255 GT + APE++ + S+D WS+GV+L PFF Sbjct: 263 GTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPFF 303 >SPAC1F7.05 |cdc22||ribonucleoside reductase large subunit Cdc22|Schizosaccharomyces pombe|chr 1|||Manual Length = 811 Score = 29.1 bits (62), Expect = 1.0 Identities = 24/111 (21%), Positives = 48/111 (43%), Gaps = 9/111 (8%) Query: 258 DPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRR--YGTLKDGVLDFKNHKWFRE 315 DP+ I +K+++G Y P ++EL ++ TT+ Y L + HK + Sbjct: 35 DPVEITQKVISGVY--PGVTTIELDNLAAETAATMTTKHPDYAILAARIAVSNLHKQTEK 92 Query: 316 IDWDSILNSRIHPPFFPKIRSPGDTTN---FDVFDEEKIKDSPVCLYEEEF 363 + S + ++H PK P + +D+ + K + +Y+ +F Sbjct: 93 V--FSTVVQQLHDYVNPKTDKPAPMISDKIYDIVMKHKDELDSAIIYDRDF 141 >SPAC4D7.01c |sec71|sec7a, SPAP8A3.15c|Sec7 domain|Schizosaccharomyces pombe|chr 1|||Manual Length = 1811 Score = 28.3 bits (60), Expect = 1.8 Identities = 9/17 (52%), Positives = 13/17 (76%) Query: 308 KNHKWFREIDWDSILNS 324 KN F+++DWD I+NS Sbjct: 1539 KNKNQFKDVDWDEIINS 1555 >SPBC577.06c |||phosphatidylinositol kinase |Schizosaccharomyces pombe|chr 2|||Manual Length = 1877 Score = 27.9 bits (59), Expect = 2.4 Identities = 19/53 (35%), Positives = 24/53 (45%) Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKG 230 L ++D NI+ID G+I DFGF I T P L E+I G Sbjct: 1727 LQFKDRHNGNIMIDDQGHILHIDFGFIFDIAPGGITFESAPFKLTTEMIAVMG 1779 >SPCC1322.12c |bub1||serine/threonine protein kinase Bub1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1044 Score = 27.1 bits (57), Expect = 4.2 Identities = 10/36 (27%), Positives = 21/36 (58%) Query: 155 EETSAKFYGAQVILALEYLHACELVYRDLKPENILI 190 +E F+ + + +E LH ++++ DLK +N L+ Sbjct: 834 DEILVVFFSIEFLRIIEALHTHKIIHGDLKADNALL 869 >SPAC31A2.05c |mis4||cohesin loading factor Mis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1583 Score = 27.1 bits (57), Expect = 4.2 Identities = 11/30 (36%), Positives = 20/30 (66%), Gaps = 2/30 (6%) Query: 98 LKQIEHSYYEKKILCGLNFPFVVYMKYYFK 127 +K+++H + KIL G+N ++Y+K Y K Sbjct: 1490 MKKLDHERF--KILAGINLCNLIYLKRYIK 1517 >SPBC359.05 |abc3||ABC transporter Abc3|Schizosaccharomyces pombe|chr 2|||Manual Length = 1465 Score = 26.6 bits (56), Expect = 5.5 Identities = 11/25 (44%), Positives = 15/25 (60%) Query: 335 RSPGDTTNFDVFDEEKIKDSPVCLY 359 RS GD N+ D +KI D P+ L+ Sbjct: 347 RSIGDIINYMAVDTQKISDLPIYLF 371 >SPBC215.11c |||aldo/keto reductase, unknown biological role|Schizosaccharomyces pombe|chr 2|||Manual Length = 306 Score = 26.6 bits (56), Expect = 5.5 Identities = 11/31 (35%), Positives = 19/31 (61%), Gaps = 2/31 (6%) Query: 212 WTLCGTPEYLAPEIILS-KGYGM-SVDWWSL 240 W CG P++L E+++S + G+ +D W L Sbjct: 106 WHPCGAPKFLRQEVLMSMRRLGVKQIDLWQL 136 >SPBC6B1.10 |prp17||splicing factor Prp17|Schizosaccharomyces pombe|chr 2|||Manual Length = 558 Score = 25.8 bits (54), Expect = 9.7 Identities = 16/51 (31%), Positives = 26/51 (50%) Query: 15 GDLIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVL 65 GD G ++ EQ S L+ + VES D KSE + + N+ + ++L Sbjct: 149 GDGAYKGPWAGYGSEQSSSPLEYSEYEEVESLDVKSEKDTESNNLGQNELL 199 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.323 0.142 0.442 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,902,222 Number of Sequences: 5004 Number of extensions: 87888 Number of successful extensions: 481 Number of sequences better than 10.0: 112 Number of HSP's better than 10.0 without gapping: 104 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 181 Number of HSP's gapped (non-prelim): 150 length of query: 366 length of database: 2,362,478 effective HSP length: 74 effective length of query: 292 effective length of database: 1,992,182 effective search space: 581717144 effective search space used: 581717144 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.9 bits) S2: 54 (25.8 bits)
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