Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001163-TA|BGIBMGA001163-PA|IPR002290|Serine/threonine
protein kinase, IPR000961|Protein kinase, C-terminal,
IPR000719|Protein kinase, IPR008271|Serine/threonine protein kinase,
active site, IPR011009|Protein kinase-like
(366 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 458 e-128
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 458 e-128
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 458 e-128
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 457 e-128
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 457 e-128
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 457 e-128
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 457 e-128
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 456 e-128
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 456 e-128
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 452 e-126
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 432 e-120
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 417 e-116
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 414 e-115
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 414 e-115
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 414 e-115
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 414 e-115
AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase, cAMP-d... 365 e-100
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 355 2e-97
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 355 2e-97
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 355 2e-97
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 353 6e-97
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 353 6e-97
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 341 2e-93
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 341 2e-93
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 289 1e-77
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 284 4e-76
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 277 4e-74
M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha pr... 277 6e-74
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 273 6e-73
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 273 6e-73
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 273 6e-73
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 273 6e-73
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 273 6e-73
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 273 6e-73
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 273 6e-73
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 273 6e-73
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 273 6e-73
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 273 6e-73
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 273 6e-73
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 273 6e-73
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 273 6e-73
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 270 5e-72
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 270 5e-72
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 270 5e-72
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 264 3e-70
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 264 3e-70
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 264 3e-70
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 264 3e-70
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 264 3e-70
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 264 3e-70
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 264 3e-70
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 264 3e-70
AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase, cAMP-de... 262 1e-69
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 262 1e-69
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 262 2e-69
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 262 2e-69
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 262 2e-69
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 262 2e-69
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 260 4e-69
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 260 6e-69
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 260 6e-69
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 260 6e-69
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 260 6e-69
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 260 6e-69
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 260 6e-69
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 260 6e-69
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 260 6e-69
Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 259 1e-68
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 259 1e-68
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 259 1e-68
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 259 1e-68
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 259 1e-68
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 259 1e-68
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 258 2e-68
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 258 2e-68
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 258 2e-68
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 258 2e-68
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 258 2e-68
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 258 2e-68
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 256 7e-68
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 256 7e-68
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 256 7e-68
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 256 7e-68
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 256 7e-68
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 256 7e-68
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 256 7e-68
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 256 7e-68
Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 256 1e-67
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 255 2e-67
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 255 2e-67
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 254 4e-67
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 254 5e-67
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 253 8e-67
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 252 1e-66
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 252 1e-66
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 252 1e-66
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 252 1e-66
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 252 1e-66
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 252 2e-66
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 250 8e-66
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 243 7e-64
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 240 5e-63
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 240 6e-63
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 240 6e-63
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 240 6e-63
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 240 6e-63
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 239 1e-62
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 239 1e-62
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 239 1e-62
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 239 1e-62
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 239 1e-62
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 239 1e-62
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 239 1e-62
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 239 1e-62
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 237 3e-62
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 237 3e-62
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 237 3e-62
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 237 6e-62
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 237 6e-62
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 236 8e-62
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 236 1e-61
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 236 1e-61
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 236 1e-61
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 236 1e-61
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 236 1e-61
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 236 1e-61
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 236 1e-61
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 236 1e-61
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 236 1e-61
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 236 1e-61
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 236 1e-61
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 236 1e-61
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 235 1e-61
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 235 1e-61
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 233 1e-60
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 233 1e-60
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 233 1e-60
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 232 2e-60
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 232 2e-60
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 232 2e-60
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 232 2e-60
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 231 3e-60
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 231 3e-60
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 231 4e-60
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 231 4e-60
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 230 5e-60
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 230 5e-60
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 230 5e-60
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 230 5e-60
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 229 2e-59
BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein. 229 2e-59
BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for IM... 229 2e-59
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 229 2e-59
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 229 2e-59
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 229 2e-59
AF208004-1|AAG35720.1| 181|Homo sapiens cAMP-dependent protein ... 227 6e-59
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 226 8e-59
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 222 1e-57
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 222 1e-57
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 222 1e-57
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 222 1e-57
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 222 1e-57
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 222 2e-57
AL450063-5|CAI16848.1| 186|Homo sapiens protein kinase, cAMP-de... 221 3e-57
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 220 7e-57
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 220 7e-57
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 220 7e-57
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 220 7e-57
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 219 1e-56
BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 ki... 218 2e-56
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 218 2e-56
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 218 2e-56
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 218 2e-56
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 217 4e-56
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 217 4e-56
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 217 4e-56
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 215 2e-55
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 215 2e-55
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 215 2e-55
AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta ... 215 2e-55
BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein. 214 5e-55
AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein. 214 5e-55
BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for IM... 210 4e-54
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 210 6e-54
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 210 6e-54
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 210 6e-54
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 210 6e-54
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 210 6e-54
AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 210 6e-54
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 210 6e-54
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 210 8e-54
AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein. 210 8e-54
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 207 4e-53
AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human seri... 207 4e-53
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 205 2e-52
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 205 2e-52
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 205 2e-52
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 205 2e-52
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 205 2e-52
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 205 2e-52
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 203 9e-52
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 202 2e-51
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 202 2e-51
BC048261-1|AAH48261.1| 492|Homo sapiens CDC42BPB protein protein. 202 2e-51
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 202 2e-51
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 202 2e-51
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 202 2e-51
BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated ... 201 3e-51
BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein. 201 3e-51
BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein. 201 3e-51
AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated ... 201 3e-51
AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated ... 201 3e-51
AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated ... 201 3e-51
AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated ... 201 3e-51
AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated ... 201 3e-51
AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated ... 201 3e-51
AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated ... 201 3e-51
U08438-1|AAB60689.1| 689|Homo sapiens beta-adrenergic receptor ... 201 4e-51
M80776-1|AAA58391.1| 689|Homo sapiens receptor kinase protein. 201 4e-51
BC090863-1|AAH90863.1| 689|Homo sapiens ADRBK1 protein protein. 201 4e-51
BC037963-1|AAH37963.1| 689|Homo sapiens adrenergic, beta, recep... 201 4e-51
X61157-1|CAA43470.1| 689|Homo sapiens beta-adrenergic receptor ... 200 6e-51
U59305-1|AAB37126.1| 496|Homo sapiens ser-thr protein kinase PK... 198 2e-50
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 198 2e-50
AL627308-4|CAH71338.1| 1638|Homo sapiens CDC42 binding protein k... 198 2e-50
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 198 2e-50
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 198 2e-50
AL451047-2|CAH71184.1| 1638|Homo sapiens CDC42 binding protein k... 198 2e-50
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 198 2e-50
AL450063-4|CAI16847.1| 175|Homo sapiens protein kinase, cAMP-de... 198 2e-50
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 198 2e-50
AL353689-8|CAI19110.1| 1638|Homo sapiens CDC42 binding protein k... 198 2e-50
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 198 2e-50
AJ518976-1|CAD57746.1| 1638|Homo sapiens CDC42 binding protein k... 198 2e-50
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 198 2e-50
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 198 2e-50
AY166586-1|AAN86031.1| 1638|Homo sapiens CDC42-binding protein k... 197 6e-50
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 196 8e-50
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 196 8e-50
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 196 8e-50
AL022329-1|CAB45657.1| 688|Homo sapiens adrenergic, beta, recep... 194 3e-49
X69117-1|CAA48870.1| 688|Homo sapiens beta-adrenergic kinase 2 ... 194 4e-49
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 194 4e-49
S72883-1|AAB31800.1| 625|Homo sapiens myotonin protein kinase p... 190 7e-48
M94203-1|AAA64884.1| 582|Homo sapiens protein kinase protein. 190 7e-48
L19268-1|AAA36206.1| 624|Homo sapiens protein kinase protein. 190 7e-48
L08835-5|AAC14450.1| 530|Homo sapiens myotonic dystrophy kinase... 190 7e-48
L08835-4|AAC14451.1| 535|Homo sapiens myotonic dystrophy kinase... 190 7e-48
L08835-3|AAC14448.1| 624|Homo sapiens myotonic dystrophy kinase... 190 7e-48
L08835-2|AAC14449.1| 629|Homo sapiens myotonic dystrophy kinase... 190 7e-48
L00727-5|AAA75237.1| 545|Homo sapiens myotonin-protein kinase, ... 190 7e-48
L00727-3|AAA75239.1| 634|Homo sapiens myotonin-protein kinase, ... 190 7e-48
L00727-2|AAA75238.1| 609|Homo sapiens myotonin-protein kinase, ... 190 7e-48
L00727-1|AAA75236.1| 639|Homo sapiens myotonin-protein kinase, ... 190 7e-48
BC062553-1|AAH62553.1| 629|Homo sapiens DMPK protein protein. 190 7e-48
BC026328-1|AAH26328.1| 655|Homo sapiens DMPK protein protein. 190 7e-48
AB209363-1|BAD92600.1| 672|Homo sapiens myotonic dystrophy prot... 190 7e-48
AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy kina... 187 6e-47
L15388-1|AAA58620.1| 590|Homo sapiens G protein-coupled recepto... 186 8e-47
BC064506-1|AAH64506.1| 590|Homo sapiens G protein-coupled recep... 186 8e-47
AL583824-2|CAI16759.1| 590|Homo sapiens G protein-coupled recep... 186 8e-47
AL355861-4|CAI15804.1| 590|Homo sapiens G protein-coupled recep... 186 8e-47
AL355273-2|CAI16487.1| 590|Homo sapiens G protein-coupled recep... 186 8e-47
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 185 3e-46
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 180 7e-45
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 178 3e-44
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 178 3e-44
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 177 7e-44
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 173 6e-43
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 173 6e-43
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 173 6e-43
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 173 6e-43
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 173 6e-43
U63973-1|AAB05929.1| 563|Homo sapiens rhodopsin kinase protein. 173 1e-42
L77503-1|AAG50439.1| 563|Homo sapiens rhodopsin kinase protein. 173 1e-42
L77502-1|AAT00534.2| 563|Homo sapiens rhodopsin kinase protein. 173 1e-42
L00727-6|AAA75240.1| 540|Homo sapiens myotonin-protein kinase, ... 171 4e-42
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 170 6e-42
U00686-1|AAA03565.1| 544|Homo sapiens putative novel receptor k... 170 8e-42
L16862-1|AAA60175.1| 576|Homo sapiens G protein-coupled recepto... 170 8e-42
BC009277-1|AAH09277.1| 576|Homo sapiens G protein-coupled recep... 170 8e-42
AF040752-1|AAC09274.1| 560|Homo sapiens G protein-coupled recep... 170 8e-42
AF040751-1|AAC09273.1| 589|Homo sapiens G protein-coupled recep... 170 8e-42
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 169 1e-41
BC017272-1|AAH17272.1| 589|Homo sapiens G protein-coupled recep... 168 2e-41
AF239744-1|AAF76426.1| 144|Homo sapiens sperm cAMP-dependent pr... 167 5e-41
X98118-1|CAA66802.1| 532|Homo sapiens G protein-coupled recepto... 166 9e-41
X97881-1|CAA66470.1| 578|Homo sapiens G-protein coupled recepto... 166 9e-41
X97880-1|CAA66469.1| 546|Homo sapiens G-protein coupled recepto... 166 9e-41
X97879-1|CAA66468.1| 500|Homo sapiens G-protein coupled recepto... 166 9e-41
U33056-1|AAC50408.1| 532|Homo sapiens G protein-coupled recepto... 166 9e-41
U33055-1|AAC50407.1| 546|Homo sapiens G protein-coupled recepto... 166 9e-41
U33054-1|AAC50406.1| 578|Homo sapiens G protein-coupled recepto... 166 9e-41
L03718-1|AAB04045.1| 500|Homo sapiens G protein-coupled recepto... 166 9e-41
BC117320-1|AAI17321.1| 578|Homo sapiens G protein-coupled recep... 166 9e-41
AK223581-1|BAD97301.1| 500|Homo sapiens G protein-coupled recep... 166 9e-41
U33168-4|AAC50412.1| 500|Homo sapiens G protein-coupled recepto... 166 1e-40
U33168-3|AAC50409.1| 546|Homo sapiens G protein-coupled recepto... 166 1e-40
U33168-2|AAC50411.1| 532|Homo sapiens G protein-coupled recepto... 166 1e-40
U33168-1|AAC50410.1| 578|Homo sapiens G protein-coupled recepto... 166 1e-40
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 165 3e-40
BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase... 164 4e-40
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 164 4e-40
AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protei... 164 4e-40
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 163 7e-40
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 163 1e-39
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 161 3e-39
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 161 3e-39
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 161 3e-39
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 161 3e-39
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 161 4e-39
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 161 4e-39
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 161 4e-39
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 161 4e-39
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 161 4e-39
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 161 4e-39
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 160 8e-39
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 160 8e-39
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 159 1e-38
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 159 1e-38
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 159 1e-38
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 159 1e-38
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 159 1e-38
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 159 1e-38
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 159 1e-38
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 159 1e-38
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 159 1e-38
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 159 1e-38
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 159 1e-38
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 159 1e-38
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 159 1e-38
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 159 1e-38
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 159 1e-38
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 159 1e-38
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 159 1e-38
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 159 1e-38
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 159 1e-38
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 159 1e-38
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 156 1e-37
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 156 1e-37
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 156 1e-37
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 156 1e-37
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 156 1e-37
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 156 1e-37
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 156 1e-37
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 156 1e-37
Y12337-1|CAA73006.1| 289|Homo sapiens myotonic dystrophy protei... 153 9e-37
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 153 1e-36
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 152 2e-36
AY098866-1|AAM21719.1| 486|Homo sapiens PKE protein kinase prot... 152 2e-36
AL590105-1|CAI13011.1| 486|Homo sapiens protein kinase (PKE) pr... 152 2e-36
AL512622-1|CAI12181.1| 486|Homo sapiens protein kinase (PKE) pr... 152 2e-36
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 152 2e-36
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 151 4e-36
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 151 4e-36
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 151 4e-36
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 151 4e-36
AY702977-1|AAU29340.1| 643|Homo sapiens protein kinase C theta ... 150 9e-36
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 150 9e-36
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 149 1e-35
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 149 1e-35
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 149 1e-35
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 149 1e-35
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 149 2e-35
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 149 2e-35
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 149 2e-35
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 149 2e-35
Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid regu... 149 2e-35
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 148 3e-35
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 148 3e-35
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 148 3e-35
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 147 5e-35
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 147 5e-35
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 147 5e-35
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 147 5e-35
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 147 5e-35
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 147 5e-35
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 146 8e-35
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 146 8e-35
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 146 8e-35
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 146 8e-35
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 146 8e-35
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 146 8e-35
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 146 8e-35
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 146 8e-35
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 146 8e-35
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 146 8e-35
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 146 8e-35
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 146 8e-35
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 146 8e-35
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 146 8e-35
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 146 8e-35
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 146 8e-35
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 146 8e-35
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 146 8e-35
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 146 8e-35
BC036797-1|AAH36797.1| 387|Homo sapiens ADRBK2 protein protein. 146 1e-34
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 145 2e-34
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 145 2e-34
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 144 3e-34
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 144 6e-34
AF439409-1|AAL48216.1| 553|Homo sapiens G-protein-coupled recep... 143 8e-34
AF282269-1|AAL33880.1| 553|Homo sapiens G protein-coupled recep... 143 8e-34
AY358353-1|AAQ88719.1| 364|Homo sapiens HSA250839 protein. 143 1e-33
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 142 2e-33
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 142 2e-33
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 142 2e-33
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 142 2e-33
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 142 2e-33
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 142 2e-33
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 142 2e-33
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 142 2e-33
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 142 2e-33
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 141 4e-33
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 141 4e-33
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 140 9e-33
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 140 9e-33
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 139 2e-32
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 139 2e-32
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 138 2e-32
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 138 2e-32
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 138 2e-32
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 138 2e-32
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 138 2e-32
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 138 2e-32
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 138 2e-32
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 138 2e-32
AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 138 2e-32
AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 138 2e-32
AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 138 2e-32
AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 138 2e-32
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 138 2e-32
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 138 2e-32
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 138 2e-32
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 138 2e-32
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 138 4e-32
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 138 4e-32
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 138 4e-32
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 138 4e-32
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 138 4e-32
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 136 9e-32
BC001737-1|AAH01737.1| 201|Homo sapiens Unknown (protein for IM... 136 9e-32
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 136 9e-32
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 136 1e-31
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 136 1e-31
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 136 1e-31
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 136 1e-31
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 136 2e-31
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 136 2e-31
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 136 2e-31
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 135 2e-31
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 135 3e-31
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 135 3e-31
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 135 3e-31
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 135 3e-31
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 135 3e-31
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 135 3e-31
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 135 3e-31
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 134 4e-31
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 133 8e-31
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 133 8e-31
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 133 1e-30
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 133 1e-30
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 133 1e-30
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 133 1e-30
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 133 1e-30
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 133 1e-30
BC045760-1|AAH45760.1| 369|Homo sapiens STK32C protein protein. 133 1e-30
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 133 1e-30
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 133 1e-30
AL512622-5|CAI12187.1| 369|Homo sapiens protein kinase (PKE) pr... 133 1e-30
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 132 1e-30
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 132 1e-30
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 132 1e-30
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 132 1e-30
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 132 1e-30
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 132 1e-30
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 132 1e-30
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 132 1e-30
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 132 2e-30
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 132 2e-30
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 132 2e-30
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 132 2e-30
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 132 2e-30
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 132 2e-30
AB209426-1|BAD92663.1| 830|Homo sapiens LATS homolog 1 variant ... 132 2e-30
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 131 3e-30
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 131 3e-30
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 131 3e-30
AF164041-1|AAD50272.1| 1130|Homo sapiens WARTS protein kinase pr... 131 3e-30
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 131 3e-30
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 131 3e-30
AF104413-1|AAD16882.1| 1130|Homo sapiens large tumor suppressor ... 131 3e-30
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 131 3e-30
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 131 3e-30
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 131 3e-30
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 131 4e-30
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 131 4e-30
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 131 4e-30
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 131 4e-30
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 458 bits (1129), Expect = e-128
Identities = 197/338 (58%), Positives = 265/338 (78%)
Query: 29 EQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
E ++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK
Sbjct: 14 ESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK 73
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
+L+K+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHL
Sbjct: 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHL 133
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR 208
R++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 209 GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA 268
GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+
Sbjct: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query: 269 GKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
GK R PSHFS +LKD++ ++LQVD T+R+G LK+GV D K HKWF DW +I ++
Sbjct: 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEA 313
Query: 329 PFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
PF PK R GDT+NFD ++EE I+ S +EF +F
Sbjct: 314 PFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 458 bits (1129), Expect = e-128
Identities = 197/338 (58%), Positives = 265/338 (78%)
Query: 29 EQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
E ++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK
Sbjct: 14 ESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK 73
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
+L+K+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHL
Sbjct: 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHL 133
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR 208
R++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 209 GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA 268
GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+
Sbjct: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query: 269 GKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
GK R PSHFS +LKD++ ++LQVD T+R+G LK+GV D K HKWF DW +I ++
Sbjct: 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEA 313
Query: 329 PFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
PF PK R GDT+NFD ++EE I+ S +EF +F
Sbjct: 314 PFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 458 bits (1129), Expect = e-128
Identities = 197/338 (58%), Positives = 265/338 (78%)
Query: 29 EQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
E ++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK
Sbjct: 14 ESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK 73
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
+L+K+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHL
Sbjct: 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHL 133
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR 208
R++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 209 GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA 268
GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+
Sbjct: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query: 269 GKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
GK R PSHFS +LKD++ ++LQVD T+R+G LK+GV D K HKWF DW +I ++
Sbjct: 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEA 313
Query: 329 PFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
PF PK R GDT+NFD ++EE I+ S +EF +F
Sbjct: 314 PFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351
>X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for
cAMP-dependent protein kinase catalytic subunit type
alpha (EC 2.7.1.37). ).
Length = 351
Score = 457 bits (1127), Expect = e-128
Identities = 196/341 (57%), Positives = 270/341 (79%)
Query: 26 AKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYY 85
++QE ++L K ++DF++ W+ +++ A L+ FER K LGTG+FG V LVKH TG +Y
Sbjct: 11 SEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHY 70
Query: 86 AMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMF 145
AMK+L+K+K+V+LKQIEH+ EK+IL +NFPF+V +++ FKDN LY V+ ++ GGEMF
Sbjct: 71 AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMF 130
Query: 146 SHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK 205
SHLR++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID+ GYI++TDFGF K
Sbjct: 131 SHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK 190
Query: 206 LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK 265
++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEK
Sbjct: 191 RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 266 IVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSR 325
IV+GK R PSHFS +LKD++ ++LQVD T+R+G LK+GV D KNHKWF DW +I +
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310
Query: 326 IHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
+ PF PK + PGDT+NFD ++EE+I+ S +EF++F
Sbjct: 311 VEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
>DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 457 bits (1127), Expect = e-128
Identities = 196/341 (57%), Positives = 270/341 (79%)
Query: 26 AKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYY 85
++QE ++L K ++DF++ W+ +++ A L+ FER K LGTG+FG V LVKH TG +Y
Sbjct: 11 SEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHY 70
Query: 86 AMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMF 145
AMK+L+K+K+V+LKQIEH+ EK+IL +NFPF+V +++ FKDN LY V+ ++ GGEMF
Sbjct: 71 AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMF 130
Query: 146 SHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK 205
SHLR++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID+ GYI++TDFGF K
Sbjct: 131 SHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK 190
Query: 206 LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK 265
++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEK
Sbjct: 191 RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 266 IVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSR 325
IV+GK R PSHFS +LKD++ ++LQVD T+R+G LK+GV D KNHKWF DW +I +
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310
Query: 326 IHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
+ PF PK + PGDT+NFD ++EE+I+ S +EF++F
Sbjct: 311 VEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
>BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 457 bits (1127), Expect = e-128
Identities = 196/341 (57%), Positives = 270/341 (79%)
Query: 26 AKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYY 85
++QE ++L K ++DF++ W+ +++ A L+ FER K LGTG+FG V LVKH TG +Y
Sbjct: 11 SEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHY 70
Query: 86 AMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMF 145
AMK+L+K+K+V+LKQIEH+ EK+IL +NFPF+V +++ FKDN LY V+ ++ GGEMF
Sbjct: 71 AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMF 130
Query: 146 SHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK 205
SHLR++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID+ GYI++TDFGF K
Sbjct: 131 SHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK 190
Query: 206 LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK 265
++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEK
Sbjct: 191 RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 266 IVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSR 325
IV+GK R PSHFS +LKD++ ++LQVD T+R+G LK+GV D KNHKWF DW +I +
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310
Query: 326 IHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
+ PF PK + PGDT+NFD ++EE+I+ S +EF++F
Sbjct: 311 VEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
>BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 457 bits (1127), Expect = e-128
Identities = 196/341 (57%), Positives = 270/341 (79%)
Query: 26 AKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYY 85
++QE ++L K ++DF++ W+ +++ A L+ FER K LGTG+FG V LVKH TG +Y
Sbjct: 11 SEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHY 70
Query: 86 AMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMF 145
AMK+L+K+K+V+LKQIEH+ EK+IL +NFPF+V +++ FKDN LY V+ ++ GGEMF
Sbjct: 71 AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMF 130
Query: 146 SHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK 205
SHLR++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID+ GYI++TDFGF K
Sbjct: 131 SHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK 190
Query: 206 LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEK 265
++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEK
Sbjct: 191 RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 266 IVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSR 325
IV+GK R PSHFS +LKD++ ++LQVD T+R+G LK+GV D KNHKWF DW +I +
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310
Query: 326 IHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
+ PF PK + PGDT+NFD ++EE+I+ S +EF++F
Sbjct: 311 VEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 456 bits (1125), Expect = e-128
Identities = 196/334 (58%), Positives = 264/334 (79%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 65 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 124
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 125 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 184
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 185 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 244
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR 272
TLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+GK R
Sbjct: 245 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR 304
Query: 273 CPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
PSHFS +LKD++ ++LQVD T+R+G LK+GV D K HKWF DW +I ++ PF P
Sbjct: 305 FPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 364
Query: 333 KIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
K R GDT+NFD ++EE I+ S +EF +F
Sbjct: 365 KFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 398
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 456 bits (1125), Expect = e-128
Identities = 196/334 (58%), Positives = 264/334 (79%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 65 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 124
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 125 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 184
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 185 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 244
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR 272
TLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+GK R
Sbjct: 245 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR 304
Query: 273 CPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
PSHFS +LKD++ ++LQVD T+R+G LK+GV D K HKWF DW +I ++ PF P
Sbjct: 305 FPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 364
Query: 333 KIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
K R GDT+NFD ++EE I+ S +EF +F
Sbjct: 365 KFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 398
>BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 452 bits (1113), Expect = e-126
Identities = 194/338 (57%), Positives = 265/338 (78%)
Query: 29 EQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
E ++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK
Sbjct: 14 ESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK 73
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
+L+K+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHL
Sbjct: 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHL 133
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR 208
R++G+F E A+FY AQ++L EYL++ +++YRDLKPEN+LID GYI++TDFGF K ++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLNSLDIIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 209 GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA 268
GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+
Sbjct: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query: 269 GKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
GK R PS+FS +LKD++ ++LQVD T+R+G LK+GV D K HKWF DW +I ++
Sbjct: 254 GKVRFPSNFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEA 313
Query: 329 PFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
PF PK R GDT+NFD ++EE I+ S +EF +F
Sbjct: 314 PFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 432 bits (1064), Expect = e-120
Identities = 183/303 (60%), Positives = 245/303 (80%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 44 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 103
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 104 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 163
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 164 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 223
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR 272
TLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+GK R
Sbjct: 224 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR 283
Query: 273 CPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
PSHFS +LKD++ ++LQVD T+R+G LK+GV D K HKWF DW +I ++ PF P
Sbjct: 284 FPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 343
Query: 333 KIR 335
K R
Sbjct: 344 KFR 346
>M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A
gamma-subunit protein.
Length = 360
Score = 417 bits (1027), Expect = e-116
Identities = 182/350 (52%), Positives = 261/350 (74%), Gaps = 5/350 (1%)
Query: 22 GYSPAK-----QEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLV 76
G +PAK +E +++L K R DF+ W + +++ A + FER + LG G+FG V LV
Sbjct: 11 GNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLV 70
Query: 77 KHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVL 136
+H TG +YAMK+L K+K+V++KQ+EH EK+IL ++FPF+V +++ FKDN YLY V+
Sbjct: 71 RHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVM 130
Query: 137 PFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYI 196
++ GGEMFS L+++G+F E A FY AQV+LA++YLH+ +L++RDLKPEN+LID+ GY+
Sbjct: 131 EYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYL 190
Query: 197 KITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFA 256
++TDFGF K ++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+ G PPF+A
Sbjct: 191 QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYA 250
Query: 257 SDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREI 316
P++IYEKIV+G+ R PS S +LKD++ +LQVD T+R+G L++GV D KNHKWF
Sbjct: 251 DQPIQIYEKIVSGRVRFPSKLSSDLKDLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATT 310
Query: 317 DWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
W +I ++ PF PK PGD +NFD ++EE+++ S +EF++F
Sbjct: 311 SWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF 360
>DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 414 bits (1020), Expect = e-115
Identities = 181/350 (51%), Positives = 260/350 (74%), Gaps = 5/350 (1%)
Query: 22 GYSPAK-----QEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLV 76
G +PAK +E +++L K R DF+ W + +++ A + FER + LG G+FG V LV
Sbjct: 2 GNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLV 61
Query: 77 KHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVL 136
+H TG +YAMK+L K+K+V++KQ+EH EK+IL ++FPF+V +++ FKDN YLY V+
Sbjct: 62 RHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVM 121
Query: 137 PFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYI 196
++ GGEMFS L+++G+F E A FY AQV+LA++YLH+ +L++RDLKPEN+LID+ GY+
Sbjct: 122 EYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYL 181
Query: 197 KITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFA 256
++TDFGF K ++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+ G PPF+A
Sbjct: 182 QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYA 241
Query: 257 SDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREI 316
P++IYEKIV+G+ R PS S +LK ++ +LQVD T+R+G L++GV D KNHKWF
Sbjct: 242 DQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATT 301
Query: 317 DWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
W +I ++ PF PK PGD +NFD ++EE+++ S +EF++F
Sbjct: 302 SWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF 351
>BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 414 bits (1020), Expect = e-115
Identities = 181/350 (51%), Positives = 260/350 (74%), Gaps = 5/350 (1%)
Query: 22 GYSPAK-----QEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLV 76
G +PAK +E +++L K R DF+ W + +++ A + FER + LG G+FG V LV
Sbjct: 2 GNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLV 61
Query: 77 KHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVL 136
+H TG +YAMK+L K+K+V++KQ+EH EK+IL ++FPF+V +++ FKDN YLY V+
Sbjct: 62 RHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVM 121
Query: 137 PFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYI 196
++ GGEMFS L+++G+F E A FY AQV+LA++YLH+ +L++RDLKPEN+LID+ GY+
Sbjct: 122 EYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYL 181
Query: 197 KITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFA 256
++TDFGF K ++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+ G PPF+A
Sbjct: 182 QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYA 241
Query: 257 SDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREI 316
P++IYEKIV+G+ R PS S +LK ++ +LQVD T+R+G L++GV D KNHKWF
Sbjct: 242 DQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATT 301
Query: 317 DWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
W +I ++ PF PK PGD +NFD ++EE+++ S +EF++F
Sbjct: 302 SWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCPKEFSEF 351
>AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 414 bits (1020), Expect = e-115
Identities = 181/350 (51%), Positives = 260/350 (74%), Gaps = 5/350 (1%)
Query: 22 GYSPAK-----QEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLV 76
G +PAK +E +++L K R DF+ W + +++ A + FER + LG G+FG V LV
Sbjct: 2 GNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLV 61
Query: 77 KHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVL 136
+H TG +YAMK+L K+K+V++KQ+EH EK+IL ++FPF+V +++ FKDN YLY V+
Sbjct: 62 RHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVM 121
Query: 137 PFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYI 196
++ GGEMFS L+++G+F E A FY AQV+LA++YLH+ +L++RDLKPEN+LID+ GY+
Sbjct: 122 EYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYL 181
Query: 197 KITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFA 256
++TDFGF K ++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+ G PPF+A
Sbjct: 182 QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYA 241
Query: 257 SDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREI 316
P++IYEKIV+G+ R PS S +LK ++ +LQVD T+R+G L++GV D KNHKWF
Sbjct: 242 DQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATT 301
Query: 317 DWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
W +I ++ PF PK PGD +NFD ++EE+++ S +EF++F
Sbjct: 302 SWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF 351
>AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein
kinase gamma isoform protein.
Length = 351
Score = 414 bits (1020), Expect = e-115
Identities = 181/350 (51%), Positives = 260/350 (74%), Gaps = 5/350 (1%)
Query: 22 GYSPAK-----QEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLV 76
G +PAK +E +++L K R DF+ W + +++ A + FER + LG G+FG V LV
Sbjct: 2 GNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLV 61
Query: 77 KHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVL 136
+H TG +YAMK+L K+K+V++KQ+EH EK+IL ++FPF+V +++ FKDN YLY V+
Sbjct: 62 RHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVM 121
Query: 137 PFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYI 196
++ GGEMFS L+++G+F E A FY AQV+LA++YLH+ +L++RDLKPEN+LID+ GY+
Sbjct: 122 EYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYL 181
Query: 197 KITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFA 256
++TDFGF K ++GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+ G PPF+A
Sbjct: 182 QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYA 241
Query: 257 SDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREI 316
P++IYEKIV+G+ R PS S +LK ++ +LQVD T+R+G L++GV D KNHKWF
Sbjct: 242 DQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATT 301
Query: 317 DWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
W +I ++ PF PK PGD +NFD ++EE+++ S +EF++F
Sbjct: 302 SWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF 351
>AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 321
Score = 365 bits (899), Expect = e-100
Identities = 174/334 (52%), Positives = 230/334 (68%), Gaps = 33/334 (9%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V ML K
Sbjct: 21 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRV---------------MLVK 65
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
K YY KIL KDN LY V+ ++ GGEMFSHLR++G
Sbjct: 66 HKATE------QYYAMKILDKQ------------KDNSNLYMVMEYVPGGEMFSHLRRIG 107
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 108 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 167
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR 272
TLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+GK R
Sbjct: 168 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR 227
Query: 273 CPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFP 332
PSHFS +LKD++ ++LQVD T+R+G LK+GV D K HKWF DW +I ++ PF P
Sbjct: 228 FPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIP 287
Query: 333 KIRSPGDTTNFDVFDEEKIKDSPVCLYEEEFADF 366
K R GDT+NFD ++EE I+ S +EF +F
Sbjct: 288 KFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 321
>BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 355 bits (872), Expect = 2e-97
Identities = 150/242 (61%), Positives = 201/242 (83%)
Query: 29 EQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
E ++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK
Sbjct: 14 ESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK 73
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
+L+K+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHL
Sbjct: 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHL 133
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR 208
R++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 209 GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA 268
GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+
Sbjct: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query: 269 GK 270
GK
Sbjct: 254 GK 255
>AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 355 bits (872), Expect = 2e-97
Identities = 150/242 (61%), Positives = 201/242 (83%)
Query: 29 EQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
E ++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK
Sbjct: 14 ESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK 73
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
+L+K+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHL
Sbjct: 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHL 133
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR 208
R++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 209 GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA 268
GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+
Sbjct: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query: 269 GK 270
GK
Sbjct: 254 GK 255
>AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 355 bits (872), Expect = 2e-97
Identities = 150/242 (61%), Positives = 201/242 (83%)
Query: 29 EQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMK 88
E ++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK
Sbjct: 14 ESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK 73
Query: 89 MLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHL 148
+L+K+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHL
Sbjct: 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHL 133
Query: 149 RKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIR 208
R++G+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 209 GRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVA 268
GRTWTLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+
Sbjct: 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
Query: 269 GK 270
GK
Sbjct: 254 GK 255
>AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 264
Score = 353 bits (868), Expect = 6e-97
Identities = 149/238 (62%), Positives = 200/238 (84%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 24 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 83
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 84 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 143
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 144 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 203
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK 270
TLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+GK
Sbjct: 204 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK 261
>AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 245
Score = 353 bits (868), Expect = 6e-97
Identities = 149/238 (62%), Positives = 200/238 (84%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 6 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 65
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 66 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 125
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 126 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 185
Query: 213 TLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK 270
TLCGTPEYLAPEIILSKGY +VDWW+LGVL++EM+AG+PPFFA P++IYEKIV+GK
Sbjct: 186 TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGK 243
>X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein.
Length = 358
Score = 341 bits (838), Expect = 2e-93
Identities = 145/293 (49%), Positives = 208/293 (70%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF+ +GTG FG V LVK ++A+K++ ++RLKQ +H + EK +L ++
Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVS 105
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ + + + D +LY ++ ++ GGE+FS+LR G+F T+ FY A++I A+EYLH+
Sbjct: 106 HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHS 165
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSV 235
E+VYRDLKPENIL+DR G+IK+TDFGF K + RTWTLCGTPEYLAPE+I SKG+G +V
Sbjct: 166 KEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAV 225
Query: 236 DWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTR 295
DWW+LG+L+FEM +G PPFF +P IY+KI+AGK P H +KD+I +L VD TR
Sbjct: 226 DWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTR 285
Query: 296 RYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDE 348
R G +K+G D K+H+WFR +DW+++ ++ PP PKI GDT+NF+ + E
Sbjct: 286 RLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYPE 338
>BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linked
protein.
Length = 358
Score = 341 bits (838), Expect = 2e-93
Identities = 145/293 (49%), Positives = 208/293 (70%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF+ +GTG FG V LVK ++A+K++ ++RLKQ +H + EK +L ++
Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVS 105
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF++ + + + D +LY ++ ++ GGE+FS+LR G+F T+ FY A++I A+EYLH+
Sbjct: 106 HPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHS 165
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMSV 235
E+VYRDLKPENIL+DR G+IK+TDFGF K + RTWTLCGTPEYLAPE+I SKG+G +V
Sbjct: 166 KEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAV 225
Query: 236 DWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTR 295
DWW+LG+L+FEM +G PPFF +P IY+KI+AGK P H +KD+I +L VD TR
Sbjct: 226 DWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTR 285
Query: 296 RYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDE 348
R G +K+G D K+H+WFR +DW+++ ++ PP PKI GDT+NF+ + E
Sbjct: 286 RLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYPE 338
>AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 214
Score = 289 bits (709), Expect = 1e-77
Identities = 123/199 (61%), Positives = 165/199 (82%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 14 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 73
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 74 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 133
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 134 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 193
Query: 213 TLCGTPEYLAPEIILSKGY 231
TLCGTPEYLAPEIILSKGY
Sbjct: 194 TLCGTPEYLAPEIILSKGY 212
>AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 209
Score = 284 bits (696), Expect = 4e-76
Identities = 121/197 (61%), Positives = 163/197 (82%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 13 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 72
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 73 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 132
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 133 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 192
Query: 213 TLCGTPEYLAPEIILSK 229
TLCGTPEYLAPEIILSK
Sbjct: 193 TLCGTPEYLAPEIILSK 209
>AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 197
Score = 277 bits (679), Expect = 4e-74
Identities = 117/193 (60%), Positives = 159/193 (82%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 5 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 64
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 65 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 124
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 125 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 184
Query: 213 TLCGTPEYLAPEI 225
TLCGTPEYLAPEI
Sbjct: 185 TLCGTPEYLAPEI 197
>M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha
protein.
Length = 207
Score = 277 bits (678), Expect = 6e-74
Identities = 118/197 (59%), Positives = 161/197 (81%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W+ +++ A L+ FER K LGTG+FG V LVKH TG +YAMK+L+K
Sbjct: 1 EFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDK 60
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V +++ FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 61 QKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG 120
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID+ GYI++TDFGF K ++GRTW
Sbjct: 121 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTW 180
Query: 213 TLCGTPEYLAPEIILSK 229
TLCGTPEYLAPEIILSK
Sbjct: 181 TLCGTPEYLAPEIILSK 197
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 368 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 427
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 428 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 487
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 488 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 547
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 607
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 608 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 667
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 668 PEDNDEPPP 676
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 353 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 412
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 413 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 472
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 473 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 532
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 533 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 592
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 593 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 652
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 653 PEDNDEPPP 661
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 368 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 427
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 428 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 487
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 488 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 547
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 607
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 608 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 667
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 668 PEDNDEPPP 676
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 353 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 412
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 413 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 472
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 473 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 532
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 533 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 592
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 593 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 652
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 653 PEDNDEPPP 661
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 368 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 427
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 428 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 487
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 488 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 547
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 607
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 608 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 667
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 668 PEDNDEPPP 676
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 368 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 427
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 428 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 487
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 488 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 547
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 607
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 608 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 667
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 668 PEDNDEPPP 676
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 341 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 400
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 401 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 460
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 461 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 520
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 521 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 580
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 581 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 640
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 641 PEDNDEPPP 649
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 368 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 427
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 428 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 487
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 488 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 547
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 607
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 608 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 667
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 668 PEDNDEPPP 676
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 341 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 400
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 401 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 460
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 461 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 520
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 521 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 580
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 581 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 640
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 641 PEDNDEPPP 649
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 368 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 427
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 428 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 487
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 488 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 547
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 607
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 608 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 667
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 668 PEDNDEPPP 676
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 341 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 400
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 401 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 460
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 461 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 520
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 521 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 580
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 581 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 640
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 641 PEDNDEPPP 649
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 368 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 427
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 428 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 487
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 488 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 547
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 548 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 607
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 608 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 667
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 668 PEDNDEPPP 676
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 273 bits (670), Expect = 6e-73
Identities = 132/309 (42%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVK-HIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+N KL+DF LG G FG V LV+ K +AMK+L+K IV +Q EH EK+I
Sbjct: 341 ANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQI 400
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ G + F+V + FKD+ YLY ++ GGE+++ LR G FE+++ +FY A V+ A
Sbjct: 401 MQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAF 460
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI--RGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPEN+++D GY K+ DFGF K I +TWT CGTPEY+APEIIL+
Sbjct: 461 AYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILN 520
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIG 286
KG+ +S D+WSLG+L++E+ G PPF DPM+ Y I+ G P + ++I
Sbjct: 521 KGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIK 580
Query: 287 HVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
+ + + + R G LK+GV D + HKWF +W+ + + PP P + SP DT+NFD F
Sbjct: 581 KLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSF 640
Query: 347 DEEKIKDSP 355
E+ + P
Sbjct: 641 PEDNDEPPP 649
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 270 bits (662), Expect = 5e-72
Identities = 128/316 (40%), Positives = 194/316 (61%), Gaps = 4/316 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K+ + +NDF+ K+LG G FG V LV+ TG+YYAMK+L KE I+ ++ H+ E
Sbjct: 142 KARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTES 201
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 202 RVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVS 261
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEI 225
ALEYLH+ ++VYRD+K EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE+
Sbjct: 262 ALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEV 321
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ YG +VDWW LGV+++EM G PF+ D R++E I+ + R P S E K ++
Sbjct: 322 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLL 381
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF-D 344
+L+ D +R G + H++F I+W ++ ++ PPF P++ S DT F D
Sbjct: 382 AGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441
Query: 345 VFDEEKIKDSPVCLYE 360
F + I +P Y+
Sbjct: 442 EFTAQSITITPPDRYD 457
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 270 bits (662), Expect = 5e-72
Identities = 128/316 (40%), Positives = 194/316 (61%), Gaps = 4/316 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K+ + +NDF+ K+LG G FG V LV+ TG+YYAMK+L KE I+ ++ H+ E
Sbjct: 142 KARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTES 201
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 202 RVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVS 261
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEI 225
ALEYLH+ ++VYRD+K EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE+
Sbjct: 262 ALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEV 321
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ YG +VDWW LGV+++EM G PF+ D R++E I+ + R P S E K ++
Sbjct: 322 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLL 381
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF-D 344
+L+ D +R G + H++F I+W ++ ++ PPF P++ S DT F D
Sbjct: 382 AGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441
Query: 345 VFDEEKIKDSPVCLYE 360
F + I +P Y+
Sbjct: 442 EFTAQSITITPPDRYD 457
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 270 bits (662), Expect = 5e-72
Identities = 128/316 (40%), Positives = 194/316 (61%), Gaps = 4/316 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K+ + +NDF+ K+LG G FG V LV+ TG+YYAMK+L KE I+ ++ H+ E
Sbjct: 142 KARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTES 201
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 202 RVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVS 261
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEI 225
ALEYLH+ ++VYRD+K EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE+
Sbjct: 262 ALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEV 321
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ YG +VDWW LGV+++EM G PF+ D R++E I+ + R P S E K ++
Sbjct: 322 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLL 381
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF-D 344
+L+ D +R G + H++F I+W ++ ++ PPF P++ S DT F D
Sbjct: 382 AGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441
Query: 345 VFDEEKIKDSPVCLYE 360
F + I +P Y+
Sbjct: 442 EFTAQSITITPPDRYD 457
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 264 bits (647), Expect = 3e-70
Identities = 124/314 (39%), Positives = 191/314 (60%), Gaps = 4/314 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G D + H +F ++W + + ++ PPF P++ S DT FD F + I
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444
Query: 352 KDSPVCLYEEEFAD 365
+P Y+E+ D
Sbjct: 445 TITPPEKYDEDGMD 458
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 264 bits (647), Expect = 3e-70
Identities = 124/314 (39%), Positives = 191/314 (60%), Gaps = 4/314 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G D + H +F ++W + + ++ PPF P++ S DT FD F + I
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444
Query: 352 KDSPVCLYEEEFAD 365
+P Y+E+ D
Sbjct: 445 TITPPEKYDEDGMD 458
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 264 bits (647), Expect = 3e-70
Identities = 124/314 (39%), Positives = 191/314 (60%), Gaps = 4/314 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G D + H +F ++W + + ++ PPF P++ S DT FD F + I
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444
Query: 352 KDSPVCLYEEEFAD 365
+P Y+E+ D
Sbjct: 445 TITPPEKYDEDGMD 458
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 264 bits (647), Expect = 3e-70
Identities = 124/314 (39%), Positives = 191/314 (60%), Gaps = 4/314 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G D + H +F ++W + + ++ PPF P++ S DT FD F + I
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444
Query: 352 KDSPVCLYEEEFAD 365
+P Y+E+ D
Sbjct: 445 TITPPEKYDEDGMD 458
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 264 bits (647), Expect = 3e-70
Identities = 124/314 (39%), Positives = 191/314 (60%), Gaps = 4/314 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G D + H +F ++W + + ++ PPF P++ S DT FD F + I
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444
Query: 352 KDSPVCLYEEEFAD 365
+P Y+E+ D
Sbjct: 445 TITPPEKYDEDGMD 458
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 264 bits (647), Expect = 3e-70
Identities = 124/314 (39%), Positives = 191/314 (60%), Gaps = 4/314 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G D + H +F ++W + + ++ PPF P++ S DT FD F + I
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444
Query: 352 KDSPVCLYEEEFAD 365
+P Y+E+ D
Sbjct: 445 TITPPEKYDEDGMD 458
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 264 bits (647), Expect = 3e-70
Identities = 124/314 (39%), Positives = 191/314 (60%), Gaps = 4/314 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G D + H +F ++W + + ++ PPF P++ S DT FD F + I
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444
Query: 352 KDSPVCLYEEEFAD 365
+P Y+E+ D
Sbjct: 445 TITPPEKYDEDGMD 458
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 264 bits (647), Expect = 3e-70
Identities = 124/314 (39%), Positives = 191/314 (60%), Gaps = 4/314 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
+R G D + H +F ++W + + ++ PPF P++ S DT FD F + I
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444
Query: 352 KDSPVCLYEEEFAD 365
+P Y+E+ D
Sbjct: 445 TITPPEKYDEDGMD 458
>AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 206
Score = 262 bits (643), Expect = 1e-69
Identities = 110/186 (59%), Positives = 152/186 (81%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 21 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 80
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 81 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 140
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTW 212
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI++TDFGF K ++GRTW
Sbjct: 141 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTW 200
Query: 213 TLCGTP 218
TLCGTP
Sbjct: 201 TLCGTP 206
>AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL
protein.
Length = 496
Score = 262 bits (642), Expect = 1e-69
Identities = 136/342 (39%), Positives = 198/342 (57%), Gaps = 9/342 (2%)
Query: 22 GYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVT 81
G S + E+ SQ L Q+ + +AK DF+ KV+G G+FG V L K +
Sbjct: 127 GPSEDEDERSSQKLHSTSQNI--NLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLD 184
Query: 82 GKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIA 140
GK YA+K+L+K+ ++ K+ +H E+ +L + PF+V + Y F+ LY+VL F+
Sbjct: 185 GKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVN 244
Query: 141 GGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITD 200
GGE+F HL++ F E A+FY A++ AL YLH+ ++VYRDLKPENIL+D G++ +TD
Sbjct: 245 GGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILVDSVGHVVLTD 304
Query: 201 FGFCK---LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
FG CK I T T CGTPEYLAPE+I + Y +VDWW LG +L+EM G PPF+
Sbjct: 305 FGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCR 364
Query: 258 DPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREID 317
D +Y+ I+ S+ I+ +L+ D R G K+ L+ +NH +F +
Sbjct: 365 DVAEMYDNILHKPLSLRPGVSLRAWSILEELLEKDRQNRLGA-KEDFLEIQNHPFFESLS 423
Query: 318 WDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSPVCL 358
W ++ +I PPF P + P D NFD F EE + S VC+
Sbjct: 424 WADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYS-VCV 464
>CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein.
Length = 429
Score = 262 bits (641), Expect = 2e-69
Identities = 135/340 (39%), Positives = 198/340 (58%), Gaps = 9/340 (2%)
Query: 24 SPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGK 83
S + E+ SQ L Q+ + +AK DF+ KV+G G+FG V L K + GK
Sbjct: 62 SEDEDERSSQKLHSTSQNI--NLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGK 119
Query: 84 YYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
+YA+K+L+K+ ++ K+ +H E+ +L + PF+V + Y F+ LY+VL F+ GG
Sbjct: 120 FYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG 179
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
E+F HL++ F E A+FY A++ AL YLH+ ++VYRDLKPENIL+D G++ +TDFG
Sbjct: 180 ELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFG 239
Query: 203 FCK---LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDP 259
CK I T T CGTPEYLAPE+I + Y +VDWW LG +L+EM G PPF+ D
Sbjct: 240 LCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDV 299
Query: 260 MRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWD 319
+Y+ I+ S+ I+ +L+ D R G K+ L+ +NH +F + W
Sbjct: 300 AEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGA-KEDFLEIQNHPFFESLSWA 358
Query: 320 SILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSPVCL 358
++ +I PPF P + P D NFD F EE + S VC+
Sbjct: 359 DLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYS-VCV 397
>BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase family, member 3 protein.
Length = 496
Score = 262 bits (641), Expect = 2e-69
Identities = 135/340 (39%), Positives = 198/340 (58%), Gaps = 9/340 (2%)
Query: 24 SPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGK 83
S + E+ SQ L Q+ + +AK DF+ KV+G G+FG V L K + GK
Sbjct: 129 SEDEDERSSQKLHSTSQNI--NLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGK 186
Query: 84 YYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
+YA+K+L+K+ ++ K+ +H E+ +L + PF+V + Y F+ LY+VL F+ GG
Sbjct: 187 FYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG 246
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
E+F HL++ F E A+FY A++ AL YLH+ ++VYRDLKPENIL+D G++ +TDFG
Sbjct: 247 ELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFG 306
Query: 203 FCK---LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDP 259
CK I T T CGTPEYLAPE+I + Y +VDWW LG +L+EM G PPF+ D
Sbjct: 307 LCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDV 366
Query: 260 MRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWD 319
+Y+ I+ S+ I+ +L+ D R G K+ L+ +NH +F + W
Sbjct: 367 AEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGA-KEDFLEIQNHPFFESLSWA 425
Query: 320 SILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSPVCL 358
++ +I PPF P + P D NFD F EE + S VC+
Sbjct: 426 DLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYS-VCV 464
>AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase-like isoform 1 variant protein.
Length = 496
Score = 262 bits (641), Expect = 2e-69
Identities = 135/340 (39%), Positives = 198/340 (58%), Gaps = 9/340 (2%)
Query: 24 SPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGK 83
S + E+ SQ L Q+ + +AK DF+ KV+G G+FG V L K + GK
Sbjct: 129 SEDEDERSSQKLHSTSQNI--NLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGK 186
Query: 84 YYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
+YA+K+L+K+ ++ K+ +H E+ +L + PF+V + Y F+ LY+VL F+ GG
Sbjct: 187 FYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG 246
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
E+F HL++ F E A+FY A++ AL YLH+ ++VYRDLKPENIL+D G++ +TDFG
Sbjct: 247 ELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFG 306
Query: 203 FCK---LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDP 259
CK I T T CGTPEYLAPE+I + Y +VDWW LG +L+EM G PPF+ D
Sbjct: 307 LCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDV 366
Query: 260 MRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWD 319
+Y+ I+ S+ I+ +L+ D R G K+ L+ +NH +F + W
Sbjct: 367 AEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGA-KEDFLEIQNHPFFESLSWA 425
Query: 320 SILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSPVCL 358
++ +I PPF P + P D NFD F EE + S VC+
Sbjct: 426 DLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYS-VCV 464
>AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein.
Length = 429
Score = 262 bits (641), Expect = 2e-69
Identities = 135/340 (39%), Positives = 198/340 (58%), Gaps = 9/340 (2%)
Query: 24 SPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGK 83
S + E+ SQ L Q+ + +AK DF+ KV+G G+FG V L K + GK
Sbjct: 62 SEDEDERSSQKLHSTSQNI--NLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGK 119
Query: 84 YYAMKMLEKEKIVRLKQIEHSYYEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGG 142
+YA+K+L+K+ ++ K+ +H E+ +L + PF+V + Y F+ LY+VL F+ GG
Sbjct: 120 FYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGG 179
Query: 143 EMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFG 202
E+F HL++ F E A+FY A++ AL YLH+ ++VYRDLKPENIL+D G++ +TDFG
Sbjct: 180 ELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFG 239
Query: 203 FCK---LIRGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDP 259
CK I T T CGTPEYLAPE+I + Y +VDWW LG +L+EM G PPF+ D
Sbjct: 240 LCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDV 299
Query: 260 MRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWD 319
+Y+ I+ S+ I+ +L+ D R G K+ L+ +NH +F + W
Sbjct: 300 AEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGA-KEDFLEIQNHPFFESLSWA 358
Query: 320 SILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSPVCL 358
++ +I PPF P + P D NFD F EE + S VC+
Sbjct: 359 DLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYS-VCV 397
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 260 bits (638), Expect = 4e-69
Identities = 126/310 (40%), Positives = 191/310 (61%), Gaps = 6/310 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
NA+ DF+ KV+G G +G V L K G +YA+K+L+K+ I++ K+ H E+ +L
Sbjct: 29 NAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLL 88
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V ++Y F+ LY+VL ++ GGE+F HL++ +F E A+FY A+V A++
Sbjct: 89 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAID 148
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPENIL+D G++ +TDFG CK T T CGTPEYLAPE++
Sbjct: 149 YLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRK 208
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LG +L+EM G PPF++ D ++YE I+ + P +V D++ +
Sbjct: 209 EPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSL 268
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L D +R G+ D L+ KNH +F I+WD + + R+ PPF P + P D +FD F
Sbjct: 269 LHKDQRQRLGSKAD-FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFT 327
Query: 348 EEKIKDSPVC 357
+E + S C
Sbjct: 328 QEAVSKSIGC 337
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 260 bits (637), Expect = 6e-69
Identities = 124/300 (41%), Positives = 184/300 (61%), Gaps = 4/300 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K + +N+FE K+LG G FG V LVK TG+YYAMK+L+KE IV ++ H+ E
Sbjct: 140 KPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTEN 199
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 200 RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVS 259
Query: 169 ALEYLHA-CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPE 224
AL+YLH+ +VYRDLK EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE
Sbjct: 260 ALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPE 319
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ YG +VDWW LGV+++EM G PF+ D +++E I+ + R P E K +
Sbjct: 320 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSL 379
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ D +R G + + H++F I W + ++ PPF P++ S DT FD
Sbjct: 380 LSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFD 439
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 260 bits (637), Expect = 6e-69
Identities = 124/300 (41%), Positives = 184/300 (61%), Gaps = 4/300 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K + +N+FE K+LG G FG V LVK TG+YYAMK+L+KE IV ++ H+ E
Sbjct: 140 KPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTEN 199
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 200 RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVS 259
Query: 169 ALEYLHA-CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPE 224
AL+YLH+ +VYRDLK EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE
Sbjct: 260 ALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPE 319
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ YG +VDWW LGV+++EM G PF+ D +++E I+ + R P E K +
Sbjct: 320 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSL 379
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ D +R G + + H++F I W + ++ PPF P++ S DT FD
Sbjct: 380 LSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFD 439
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 260 bits (637), Expect = 6e-69
Identities = 124/300 (41%), Positives = 184/300 (61%), Gaps = 4/300 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K + +N+FE K+LG G FG V LVK TG+YYAMK+L+KE IV ++ H+ E
Sbjct: 140 KPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTEN 199
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 200 RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVS 259
Query: 169 ALEYLHA-CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPE 224
AL+YLH+ +VYRDLK EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE
Sbjct: 260 ALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPE 319
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ YG +VDWW LGV+++EM G PF+ D +++E I+ + R P E K +
Sbjct: 320 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSL 379
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ D +R G + + H++F I W + ++ PPF P++ S DT FD
Sbjct: 380 LSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFD 439
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 260 bits (637), Expect = 6e-69
Identities = 118/292 (40%), Positives = 181/292 (61%), Gaps = 3/292 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+R G D + H +F ++W + + ++ PPF P++ S DT FD
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFD 436
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 260 bits (637), Expect = 6e-69
Identities = 118/292 (40%), Positives = 181/292 (61%), Gaps = 3/292 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+R G D + H +F ++W + + ++ PPF P++ S DT FD
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFD 436
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 260 bits (637), Expect = 6e-69
Identities = 118/292 (40%), Positives = 181/292 (61%), Gaps = 3/292 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+R G D + H +F ++W + + ++ PPF P++ S DT FD
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFD 436
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 260 bits (637), Expect = 6e-69
Identities = 118/292 (40%), Positives = 181/292 (61%), Gaps = 3/292 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN+++D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+R G D + H +F ++W + + ++ PPF P++ S DT FD
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFD 436
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 260 bits (637), Expect = 6e-69
Identities = 124/300 (41%), Positives = 184/300 (61%), Gaps = 4/300 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K + +N+FE K+LG G FG V LVK TG+YYAMK+L+KE IV ++ H+ E
Sbjct: 140 KPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTEN 199
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 200 RVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVS 259
Query: 169 ALEYLHA-CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPE 224
AL+YLH+ +VYRDLK EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE
Sbjct: 260 ALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPE 319
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ YG +VDWW LGV+++EM G PF+ D +++E I+ + R P E K +
Sbjct: 320 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSL 379
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ D +R G + + H++F I W + ++ PPF P++ S DT FD
Sbjct: 380 LSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFD 439
>Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 259 bits (634), Expect = 1e-68
Identities = 126/310 (40%), Positives = 190/310 (61%), Gaps = 6/310 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
NA+ DF+ KV+G G +G V L K G +YA+K+L+K+ I++ K+ H E+ +L
Sbjct: 29 NAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLL 88
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V ++Y F+ LY+VL ++ GGE+F HL++ +F E A+FY A+V A+
Sbjct: 89 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIG 148
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPENIL+D G++ +TDFG CK T T CGTPEYLAPE++
Sbjct: 149 YLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRK 208
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LG +L+EM G PPF++ D ++YE I+ + P +V D++ +
Sbjct: 209 EPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSL 268
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L D +R G+ D L+ KNH +F I+WD + + R+ PPF P + P D +FD F
Sbjct: 269 LHKDQRQRLGSKAD-FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFT 327
Query: 348 EEKIKDSPVC 357
+E + S C
Sbjct: 328 QEAVSKSIGC 337
>Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 427
Score = 259 bits (634), Expect = 1e-68
Identities = 126/310 (40%), Positives = 190/310 (61%), Gaps = 6/310 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
NA+ DF+ KV+G G +G V L K G +YA+K+L+K+ I++ K+ H E+ +L
Sbjct: 89 NAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLL 148
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V ++Y F+ LY+VL ++ GGE+F HL++ +F E A+FY A+V A+
Sbjct: 149 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIG 208
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPENIL+D G++ +TDFG CK T T CGTPEYLAPE++
Sbjct: 209 YLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRK 268
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LG +L+EM G PPF++ D ++YE I+ + P +V D++ +
Sbjct: 269 EPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSL 328
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L D +R G+ D L+ KNH +F I+WD + + R+ PPF P + P D +FD F
Sbjct: 329 LHKDQRQRLGSKAD-FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFT 387
Query: 348 EEKIKDSPVC 357
+E + S C
Sbjct: 388 QEAVSKSIGC 397
>BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein.
Length = 367
Score = 259 bits (634), Expect = 1e-68
Identities = 126/310 (40%), Positives = 190/310 (61%), Gaps = 6/310 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
NA+ DF+ KV+G G +G V L K G +YA+K+L+K+ I++ K+ H E+ +L
Sbjct: 29 NAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLL 88
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V ++Y F+ LY+VL ++ GGE+F HL++ +F E A+FY A+V A+
Sbjct: 89 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIG 148
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPENIL+D G++ +TDFG CK T T CGTPEYLAPE++
Sbjct: 149 YLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRK 208
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LG +L+EM G PPF++ D ++YE I+ + P +V D++ +
Sbjct: 209 EPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSL 268
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L D +R G+ D L+ KNH +F I+WD + + R+ PPF P + P D +FD F
Sbjct: 269 LHKDQRQRLGSKAD-FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFT 327
Query: 348 EEKIKDSPVC 357
+E + S C
Sbjct: 328 QEAVSKSIGC 337
>BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 259 bits (634), Expect = 1e-68
Identities = 126/310 (40%), Positives = 190/310 (61%), Gaps = 6/310 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
NA+ DF+ KV+G G +G V L K G +YA+K+L+K+ I++ K+ H E+ +L
Sbjct: 29 NAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLL 88
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V ++Y F+ LY+VL ++ GGE+F HL++ +F E A+FY A+V A+
Sbjct: 89 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIG 148
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPENIL+D G++ +TDFG CK T T CGTPEYLAPE++
Sbjct: 149 YLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRK 208
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LG +L+EM G PPF++ D ++YE I+ + P +V D++ +
Sbjct: 209 EPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSL 268
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L D +R G+ D L+ KNH +F I+WD + + R+ PPF P + P D +FD F
Sbjct: 269 LHKDQRQRLGSKAD-FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFT 327
Query: 348 EEKIKDSPVC 357
+E + S C
Sbjct: 328 QEAVSKSIGC 337
>AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein.
Length = 427
Score = 259 bits (634), Expect = 1e-68
Identities = 126/310 (40%), Positives = 190/310 (61%), Gaps = 6/310 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
NA+ DF+ KV+G G +G V L K G +YA+K+L+K+ I++ K+ H E+ +L
Sbjct: 89 NAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLL 148
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V ++Y F+ LY+VL ++ GGE+F HL++ +F E A+FY A+V A+
Sbjct: 149 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIG 208
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPENIL+D G++ +TDFG CK T T CGTPEYLAPE++
Sbjct: 209 YLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRK 268
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LG +L+EM G PPF++ D ++YE I+ + P +V D++ +
Sbjct: 269 EPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSL 328
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L D +R G+ D L+ KNH +F I+WD + + R+ PPF P + P D +FD F
Sbjct: 329 LHKDQRQRLGSKAD-FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFT 387
Query: 348 EEKIKDSPVC 357
+E + S C
Sbjct: 388 QEAVSKSIGC 397
>AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein.
Length = 367
Score = 259 bits (634), Expect = 1e-68
Identities = 126/310 (40%), Positives = 190/310 (61%), Gaps = 6/310 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
NA+ DF+ KV+G G +G V L K G +YA+K+L+K+ I++ K+ H E+ +L
Sbjct: 29 NAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLL 88
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V ++Y F+ LY+VL ++ GGE+F HL++ +F E A+FY A+V A+
Sbjct: 89 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIG 148
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPENIL+D G++ +TDFG CK T T CGTPEYLAPE++
Sbjct: 149 YLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRK 208
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LG +L+EM G PPF++ D ++YE I+ + P +V D++ +
Sbjct: 209 EPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSL 268
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L D +R G+ D L+ KNH +F I+WD + + R+ PPF P + P D +FD F
Sbjct: 269 LHKDQRQRLGSKAD-FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFT 327
Query: 348 EEKIKDSPVC 357
+E + S C
Sbjct: 328 QEAVSKSIGC 337
>Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 258 bits (633), Expect = 2e-68
Identities = 112/228 (49%), Positives = 161/228 (70%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L D + +GTG FG V LVK ++A+K++ ++R KQ +H + EK +L +
Sbjct: 45 RLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEV 104
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF++ + + + + +LY ++ ++ GGE+FS+LR G F T+ FY A++I A+EYLH
Sbjct: 105 SHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLH 164
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMS 234
+ E+VYRDLKPENIL+DR G+IK+TDFGF K + RTWTLCGTPEYLAPE+I SKG+G +
Sbjct: 165 SKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRA 224
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
VDWW+LG+L+FEM +G PPFF +P IY+KI+AGK P H +K
Sbjct: 225 VDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHLDFHVK 272
>Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 258 bits (633), Expect = 2e-68
Identities = 112/228 (49%), Positives = 161/228 (70%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L D + +GTG FG V LVK ++A+K++ ++R KQ +H + EK +L +
Sbjct: 45 RLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEV 104
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF++ + + + + +LY ++ ++ GGE+FS+LR G F T+ FY A++I A+EYLH
Sbjct: 105 SHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLH 164
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMS 234
+ E+VYRDLKPENIL+DR G+IK+TDFGF K + RTWTLCGTPEYLAPE+I SKG+G +
Sbjct: 165 SKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRA 224
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
VDWW+LG+L+FEM +G PPFF +P IY+KI+AGK P H +K
Sbjct: 225 VDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHLDFHVK 272
>BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 258 bits (633), Expect = 2e-68
Identities = 112/228 (49%), Positives = 161/228 (70%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L D + +GTG FG V LVK ++A+K++ ++R KQ +H + EK +L +
Sbjct: 45 RLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEV 104
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF++ + + + + +LY ++ ++ GGE+FS+LR G F T+ FY A++I A+EYLH
Sbjct: 105 SHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLH 164
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMS 234
+ E+VYRDLKPENIL+DR G+IK+TDFGF K + RTWTLCGTPEYLAPE+I SKG+G +
Sbjct: 165 SKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRA 224
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
VDWW+LG+L+FEM +G PPFF +P IY+KI+AGK P H +K
Sbjct: 225 VDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHLDFHVK 272
>BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 258 bits (633), Expect = 2e-68
Identities = 112/228 (49%), Positives = 161/228 (70%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L D + +GTG FG V LVK ++A+K++ ++R KQ +H + EK +L +
Sbjct: 45 RLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEV 104
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF++ + + + + +LY ++ ++ GGE+FS+LR G F T+ FY A++I A+EYLH
Sbjct: 105 SHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLH 164
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLCGTPEYLAPEIILSKGYGMS 234
+ E+VYRDLKPENIL+DR G+IK+TDFGF K + RTWTLCGTPEYLAPE+I SKG+G +
Sbjct: 165 SKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRA 224
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
VDWW+LG+L+FEM +G PPFF +P IY+KI+AGK P H +K
Sbjct: 225 VDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHLDFHVK 272
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 258 bits (632), Expect = 2e-68
Identities = 118/292 (40%), Positives = 180/292 (61%), Gaps = 3/292 (1%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
+NDF+ K+LG G FG V LV+ +GKYYAMK+L+KE I+ ++ H+ E ++L
Sbjct: 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+ +KY F+ L +V+ ++ GGE+F HL + F E +FYGA+++ AL+YLH+
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEIILSKGYG 232
++VYRDLK EN++ D+ G+IKITDFG CK + T T CGTPEYLAPE++ YG
Sbjct: 265 GKIVYRDLKLENLMRDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWW LGV+++EM G PF+ D +++E I+ + P S + K ++ +L D
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+R G D + H +F ++W + + ++ PPF P++ S DT FD
Sbjct: 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFD 436
>AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 393
Score = 258 bits (632), Expect = 2e-68
Identities = 126/310 (40%), Positives = 190/310 (61%), Gaps = 6/310 (1%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
NA+ DF+ KV+G G +G V L K G +YA+K+L+K+ I++ K+ H E+ +L
Sbjct: 55 NAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLL 114
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V ++Y F+ LY+VL ++ GGE+F HL++ +F E A+FY A+V A+
Sbjct: 115 KNVRHPFLVGLRYSFQTPEELYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIG 174
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPENIL+D G++ +TDFG CK T T CGTPEYLAPE++
Sbjct: 175 YLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRK 234
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LG +L+EM G PPF++ D ++YE I+ + P +V D++ +
Sbjct: 235 EPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSL 294
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L D +R G+ D L+ KNH +F I+WD + + R+ PPF P + P D +FD F
Sbjct: 295 LHKDQRQRPGSKAD-FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFT 353
Query: 348 EEKIKDSPVC 357
+E + S C
Sbjct: 354 QEAVSKSIGC 363
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 256 bits (628), Expect = 7e-68
Identities = 126/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 184 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 243
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 244 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 303
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 304 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 363
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 364 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 423
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P D +FD
Sbjct: 424 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDP 482
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 483 EFTEEPVPNS 492
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 256 bits (628), Expect = 7e-68
Identities = 126/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 89 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 148
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 149 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 208
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 209 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 268
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 269 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P D +FD
Sbjct: 329 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDP 387
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 388 EFTEEPVPNS 397
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 256 bits (628), Expect = 7e-68
Identities = 126/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 184 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 243
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 244 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 303
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 304 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 363
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 364 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 423
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P D +FD
Sbjct: 424 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDP 482
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 483 EFTEEPVPNS 492
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 256 bits (628), Expect = 7e-68
Identities = 126/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 184 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 243
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 244 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 303
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 304 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 363
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 364 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 423
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P D +FD
Sbjct: 424 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDP 482
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 483 EFTEEPVPNS 492
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 256 bits (628), Expect = 7e-68
Identities = 126/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 103 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 162
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 163 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 222
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 223 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 282
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 283 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 342
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P D +FD
Sbjct: 343 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDP 401
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 402 EFTEEPVPNS 411
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 256 bits (628), Expect = 7e-68
Identities = 126/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 89 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 148
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 149 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 208
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 209 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 268
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 269 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P D +FD
Sbjct: 329 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDP 387
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 388 EFTEEPVPNS 397
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 256 bits (628), Expect = 7e-68
Identities = 126/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 79 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 138
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 139 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 198
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 199 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 258
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 259 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 318
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P D +FD
Sbjct: 319 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDP 377
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 378 EFTEEPVPNS 387
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 256 bits (628), Expect = 7e-68
Identities = 126/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 89 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 148
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 149 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 208
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 209 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 268
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 269 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P D +FD
Sbjct: 329 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDP 387
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 388 EFTEEPVPNS 397
>Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 366
Score = 256 bits (626), Expect = 1e-67
Identities = 126/310 (40%), Positives = 190/310 (61%), Gaps = 7/310 (2%)
Query: 53 NAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC 112
NA+ DF+ KV+G G +G V L K G +YA+K+L+K+ I++ K+ H E+ +L
Sbjct: 29 NAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKE-SHIMAERSVLL 87
Query: 113 -GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V ++Y F+ LY+VL ++ GGE+F HL++ +F E A+FY A+V A+
Sbjct: 88 KNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIG 147
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILS 228
YLH+ ++YRDLKPENIL+D G++ +TDFG CK T T CGTPEYLAPE++
Sbjct: 148 YLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRK 207
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LG +L+EM G PPF++ D ++YE I+ + P +V D++ +
Sbjct: 208 EPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSL 267
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFD 347
L D +R G+ D L+ KNH +F I+WD + + R+ PPF P + P D +FD F
Sbjct: 268 LHKDQRQRLGSKAD-FLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFT 326
Query: 348 EEKIKDSPVC 357
+E + S C
Sbjct: 327 QEAVSKSIGC 336
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 255 bits (624), Expect = 2e-67
Identities = 125/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 89 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 148
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 149 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 208
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 209 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 268
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 269 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P + +FD
Sbjct: 329 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNELRHFDP 387
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 388 EFTEEPVPNS 397
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 255 bits (624), Expect = 2e-67
Identities = 125/310 (40%), Positives = 192/310 (61%), Gaps = 6/310 (1%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S +AK +DF KV+G G+FG V L +H +YA+K+L+K+ I++ K+ +H E+
Sbjct: 89 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN 148
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
+L + PF+V + + F+ LY+VL +I GGE+F HL++ F E A+FY A++
Sbjct: 149 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS 208
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEI 225
AL YLH+ +VYRDLKPENIL+D G+I +TDFG CK T T CGTPEYLAPE+
Sbjct: 209 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 268
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ + Y +VDWW LG +L+EM G PPF++ + +Y+ I+ + + + + ++
Sbjct: 269 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD- 344
+LQ D T+R G KD ++ K+H +F I+WD ++N +I PPF P + P + +FD
Sbjct: 329 EGLLQKDRTKRLGA-KDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNELRHFDP 387
Query: 345 VFDEEKIKDS 354
F EE + +S
Sbjct: 388 EFTEEPVPNS 397
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 254 bits (622), Expect = 4e-67
Identities = 128/303 (42%), Positives = 182/303 (60%), Gaps = 4/303 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
S++ + E LG G FG V LVK +AMK + K+ IV KQ EH Y EK+IL
Sbjct: 446 SSSPFQNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRIL 505
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
L PF+V + FKDN Y+Y +L GGE++S LR G F+E ++KF A V A +
Sbjct: 506 EELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFD 565
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG--RTWTLCGTPEYLAPEIILSK 229
YLH ++YRDLKPEN+++D GY+K+ DFGF K I +TWT CGTPEY+APE+IL+K
Sbjct: 566 YLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNK 625
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIGH 287
G+ SVD+WSLG+L++E+ G+PPF D M Y I+ G K P + +D+I
Sbjct: 626 GHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRR 685
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFD 347
+ + + T R G LK+G+ D K H+W +W+ + + P +++ P D + FD +
Sbjct: 686 LCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYP 745
Query: 348 EEK 350
EK
Sbjct: 746 PEK 748
>AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 283
Score = 254 bits (621), Expect = 5e-67
Identities = 117/273 (42%), Positives = 172/273 (63%), Gaps = 4/273 (1%)
Query: 87 MKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFS 146
MK+L+K IV +Q EH EK+I+ G + F+V + FKD+ YLY ++ GGE+++
Sbjct: 1 MKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWT 60
Query: 147 HLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL 206
LR G FE+++ +FY A V+ A YLH+ ++YRDLKPEN+++D GY K+ DFGF K
Sbjct: 61 ILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKK 120
Query: 207 I--RGRTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYE 264
I +TWT CGTPEY+APEIIL+KG+ +S D+WSLG+L++E+ G PPF DPM+ Y
Sbjct: 121 IGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYN 180
Query: 265 KIVAG--KYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSIL 322
I+ G P + ++I + + + + R G LK+GV D + HKWF +W+ +
Sbjct: 181 IILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLR 240
Query: 323 NSRIHPPFFPKIRSPGDTTNFDVFDEEKIKDSP 355
+ PP P + SP DT+NFD F E+ + P
Sbjct: 241 KGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPP 273
>AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein.
Length = 481
Score = 253 bits (619), Expect = 8e-67
Identities = 127/304 (41%), Positives = 188/304 (61%), Gaps = 7/304 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV--TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGLN 115
FE +VLG G +G VF V+ + GK YAMK+L K KIVR K H+ E+ IL +
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVK 126
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + Y F+ LY +L ++GGE+F+HL + G F E +A FY A++ LAL +LH+
Sbjct: 127 HPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHS 186
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGYG 232
++YRDLKPENI++ G+IK+TDFG CK + G T T CGT EY+APEI++ G+
Sbjct: 187 QGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN 246
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
+VDWWSLG L+++M G PPF A + + +KI+ GK P + + + +D++ L+ +
Sbjct: 247 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN 306
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEKI 351
++R G D + H +FR ++WD +L R+ PPF P ++S D + FD F +
Sbjct: 307 PSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTP 366
Query: 352 KDSP 355
DSP
Sbjct: 367 VDSP 370
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 252 bits (618), Expect = 1e-66
Identities = 127/307 (41%), Positives = 189/307 (61%), Gaps = 8/307 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILC 112
+ FE +VLG G +G VF V+ + GK YAMK+L K KIVR K H+ E+ IL
Sbjct: 65 HSFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILE 124
Query: 113 GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
+ PF+V + Y F+ LY +L ++GGE+F+HL + G F E +A FY A++ LAL +
Sbjct: 125 SVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGH 184
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSK 229
LH+ ++YRDLKPENI++ G+IK+TDFG CK + G T T CGT EY+APEI++
Sbjct: 185 LHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRS 244
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
G+ +VDWWSLG L+++M G PPF A + + +KI+ GK P + + + +D++ L
Sbjct: 245 GHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFL 304
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDE 348
+ + ++R G D + H +FR ++WD +L R+ PPF P ++S D + FD F
Sbjct: 305 KRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTR 364
Query: 349 EKIKDSP 355
+ DSP
Sbjct: 365 QTPVDSP 371
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 252 bits (617), Expect = 1e-66
Identities = 127/305 (41%), Positives = 188/305 (61%), Gaps = 8/305 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGL 114
FE +VLG G +G VF V+ + GK YAMK+L K KIVR K H+ E+ IL +
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF+V + Y F+ LY +L ++GGE+F+HL + G F E +A FY A++ LAL +LH
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGY 231
+ ++YRDLKPENI++ G+IK+TDFG CK + G T T CGT EY+APEI++ G+
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 246
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
+VDWWSLG L+++M G PPF A + + +KI+ GK P + + + +D++ L+
Sbjct: 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 306
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEK 350
+ ++R G D + H +FR ++WD +L R+ PPF P ++S D + FD F +
Sbjct: 307 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQT 366
Query: 351 IKDSP 355
DSP
Sbjct: 367 PVDSP 371
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 252 bits (617), Expect = 1e-66
Identities = 127/305 (41%), Positives = 188/305 (61%), Gaps = 8/305 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGL 114
FE +VLG G +G VF V+ + GK YAMK+L K KIVR K H+ E+ IL +
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF+V + Y F+ LY +L ++GGE+F+HL + G F E +A FY A++ LAL +LH
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGY 231
+ ++YRDLKPENI++ G+IK+TDFG CK + G T T CGT EY+APEI++ G+
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 246
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
+VDWWSLG L+++M G PPF A + + +KI+ GK P + + + +D++ L+
Sbjct: 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 306
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEK 350
+ ++R G D + H +FR ++WD +L R+ PPF P ++S D + FD F +
Sbjct: 307 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQT 366
Query: 351 IKDSP 355
DSP
Sbjct: 367 PVDSP 371
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 252 bits (617), Expect = 1e-66
Identities = 127/305 (41%), Positives = 188/305 (61%), Gaps = 8/305 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGL 114
FE +VLG G +G VF V+ + GK YAMK+L K KIVR K H+ E+ IL +
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF+V + Y F+ LY +L ++GGE+F+HL + G F E +A FY A++ LAL +LH
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGY 231
+ ++YRDLKPENI++ G+IK+TDFG CK + G T T CGT EY+APEI++ G+
Sbjct: 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 246
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
+VDWWSLG L+++M G PPF A + + +KI+ GK P + + + +D++ L+
Sbjct: 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 306
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEK 350
+ ++R G D + H +FR ++WD +L R+ PPF P ++S D + FD F +
Sbjct: 307 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQT 366
Query: 351 IKDSP 355
DSP
Sbjct: 367 PVDSP 371
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 252 bits (617), Expect = 1e-66
Identities = 127/305 (41%), Positives = 188/305 (61%), Gaps = 8/305 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGL 114
FE +VLG G +G VF V+ + GK YAMK+L K KIVR K H+ E+ IL +
Sbjct: 80 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 139
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
PF+V + Y F+ LY +L ++GGE+F+HL + G F E +A FY A++ LAL +LH
Sbjct: 140 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 199
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGY 231
+ ++YRDLKPENI++ G+IK+TDFG CK + G T T CGT EY+APEI++ G+
Sbjct: 200 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 259
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
+VDWWSLG L+++M G PPF A + + +KI+ GK P + + + +D++ L+
Sbjct: 260 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 319
Query: 292 DTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEK 350
+ ++R G D + H +FR ++WD +L R+ PPF P ++S D + FD F +
Sbjct: 320 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQT 379
Query: 351 IKDSP 355
DSP
Sbjct: 380 PVDSP 384
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 252 bits (616), Expect = 2e-66
Identities = 127/303 (41%), Positives = 181/303 (59%), Gaps = 4/303 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
S++ + E L G FG V LVK +AMK + K+ IV KQ EH Y EK+IL
Sbjct: 446 SSSPFQNLEIIATLAVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRIL 505
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
L PF+V + FKDN Y+Y +L GGE++S LR G F+E ++KF A V A +
Sbjct: 506 EELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFD 565
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG--RTWTLCGTPEYLAPEIILSK 229
YLH ++YRDLKPEN+++D GY+K+ DFGF K I +TWT CGTPEY+APE+IL+K
Sbjct: 566 YLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNK 625
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIGH 287
G+ SVD+WSLG+L++E+ G+PPF D M Y I+ G K P + +D+I
Sbjct: 626 GHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRR 685
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFD 347
+ + + T R G LK+G+ D K H+W +W+ + + P +++ P D + FD +
Sbjct: 686 LCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYP 745
Query: 348 EEK 350
EK
Sbjct: 746 PEK 748
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 250 bits (611), Expect = 8e-66
Identities = 122/300 (40%), Positives = 182/300 (60%), Gaps = 5/300 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K + +N+FE K+LG G FG V LVK T YYAMK+L+KE IV ++ H+ E
Sbjct: 78 KPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATA-YYAMKILKKEVIVAKDEVAHTLTEN 136
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++ PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 137 RVQQNSRHPFLTRLKYSFQTHDRLCFVMEYANGGELFFHLSRERVFAEDRARFYGAEIVS 196
Query: 169 ALEYLHACE-LVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPE 224
AL+YLH+ + +VYRDLK EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE
Sbjct: 197 ALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPE 256
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ YG +VDWW LGV+++EM G PF+ D +++E I+ + R P E K +
Sbjct: 257 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSL 316
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ D +R G + + H++F I W + ++ PPF P++ S DT FD
Sbjct: 317 LSGLLKKDPKQRLGGGSEDAKEIMQHRFFTGIVWQHVYEKKLSPPFKPQVTSETDTRYFD 376
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 243 bits (595), Expect = 7e-64
Identities = 121/274 (44%), Positives = 169/274 (61%), Gaps = 4/274 (1%)
Query: 52 SNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL 111
S++ + E LG G FG V LVK +AMK + K+ IV KQ EH Y EK+IL
Sbjct: 446 SSSPFQNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRIL 505
Query: 112 CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
L PF+V + FKDN Y+Y +L GGE++S LR G F+E ++KF A V A +
Sbjct: 506 EELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFD 565
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG--RTWTLCGTPEYLAPEIILSK 229
YLH ++YRDLKPEN+++D GY+K+ DFGF K I +TWT CGTPEY+APE+IL+K
Sbjct: 566 YLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNK 625
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAG--KYRCPSHFSVELKDIIGH 287
G+ SVD+WSLG+L++E+ G+PPF D M Y I+ G K P + +D+I
Sbjct: 626 GHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRR 685
Query: 288 VLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSI 321
+ + + T R G LK+G+ D K H+W +W+ +
Sbjct: 686 LCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGL 719
>AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6
protein protein.
Length = 672
Score = 240 bits (588), Expect = 5e-63
Identities = 123/310 (39%), Positives = 183/310 (59%), Gaps = 9/310 (2%)
Query: 45 SWDDKSESN----AKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQ 100
S D K SN KL DF VLG G+FG V L T + YA+K+L+K+ +++
Sbjct: 321 SEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDD 380
Query: 101 IEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSA 159
+E + EK++L L+ P F+ + F+ LY+V+ ++ GG++ H++++GKF+E A
Sbjct: 381 VECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQA 440
Query: 160 KFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCG 216
FY A++ + L +LH ++YRDLK +N+++D G+IKI DFG CK ++ G T T CG
Sbjct: 441 VFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCG 500
Query: 217 TPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH 276
TP+Y+APEII + YG SVDWW+ GVLL+EM AG PPF D +++ I+ P
Sbjct: 501 TPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS 560
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
S E + ++ +R G +G D + H +FR IDW+ + N I PPF PK+R
Sbjct: 561 LSKEAVSVCKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVRG 620
Query: 337 PGDTTNFDVF 346
G NFD F
Sbjct: 621 KG-AENFDKF 629
>M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase
alpha-II protein.
Length = 502
Score = 240 bits (587), Expect = 6e-63
Identities = 130/362 (35%), Positives = 206/362 (56%), Gaps = 12/362 (3%)
Query: 2 ADSEIKRHINSPRGDLIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFER 61
A SE + + + HGG P E ++ +K + E+ ++ + FE
Sbjct: 15 AGSEDELEEGGQLNESMDHGGVGP--YELGMEHCEKF--EISETSVNRGPEKIRPECFEL 70
Query: 62 QKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGLNFP 117
+VLG G +G VF V+ + TGK +AMK+L+K IVR K H+ E+ IL + P
Sbjct: 71 LRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHP 130
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F+V + Y F+ LY +L +++GGE+F L + G F E +A FY A++ +AL +LH
Sbjct: 131 FIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKG 190
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGYGMS 234
++YRDLKPENI+++ G++K+TDFG CK + G T T CGT EY+APEI++ G+ +
Sbjct: 191 IIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRA 250
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTT 294
VDWWSLG L+++M G PPF + + +KI+ K P + + E +D++ +L+ +
Sbjct: 251 VDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAA 310
Query: 295 RRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKD 353
R G + + H +FR I+W+ +L ++ PPF P ++S D + FD F + D
Sbjct: 311 SRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVD 370
Query: 354 SP 355
SP
Sbjct: 371 SP 372
>M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase
alpha-I protein.
Length = 525
Score = 240 bits (587), Expect = 6e-63
Identities = 130/362 (35%), Positives = 206/362 (56%), Gaps = 12/362 (3%)
Query: 2 ADSEIKRHINSPRGDLIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFER 61
A SE + + + HGG P E ++ +K + E+ ++ + FE
Sbjct: 38 AGSEDELEEGGQLNESMDHGGVGP--YELGMEHCEKF--EISETSVNRGPEKIRPECFEL 93
Query: 62 QKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGLNFP 117
+VLG G +G VF V+ + TGK +AMK+L+K IVR K H+ E+ IL + P
Sbjct: 94 LRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHP 153
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F+V + Y F+ LY +L +++GGE+F L + G F E +A FY A++ +AL +LH
Sbjct: 154 FIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKG 213
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGYGMS 234
++YRDLKPENI+++ G++K+TDFG CK + G T T CGT EY+APEI++ G+ +
Sbjct: 214 IIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRA 273
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTT 294
VDWWSLG L+++M G PPF + + +KI+ K P + + E +D++ +L+ +
Sbjct: 274 VDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAA 333
Query: 295 RRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKD 353
R G + + H +FR I+W+ +L ++ PPF P ++S D + FD F + D
Sbjct: 334 SRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVD 393
Query: 354 SP 355
SP
Sbjct: 394 SP 395
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 240 bits (587), Expect = 6e-63
Identities = 126/314 (40%), Positives = 179/314 (57%), Gaps = 8/314 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQIEHSY 105
+ A + FE KVLG G+FG VFLVK I+ + YAMK+L+K + +++ +
Sbjct: 58 EGHEKADPSQFELLKVLGQGSFGKVFLVKKILGSDARQLYAMKVLKKATL-KVRDRVRTK 116
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ IL +N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A+
Sbjct: 117 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+ LAL++LH+ ++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PE++ +G+ S DWWS GVL+FEM G PF D I+ K P S E +
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ + + + R G DGV + K H +F IDW+ + IHPPF P P DT
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFY 356
Query: 343 FD-VFDEEKIKDSP 355
FD F + KDSP
Sbjct: 357 FDPEFTAKTPKDSP 370
Score = 122 bits (295), Expect = 2e-27
Identities = 81/252 (32%), Positives = 129/252 (51%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE +L P
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 475
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D Y+Y V + GGE+ + + F E A + +EYLHA +
Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D +G I+I DFGF K +R G T C T ++APE++ +GY
Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 595
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCPSHF----SVELKDI 284
+ D WSLGVLL+ M G+ PF P I +I +GK+ + S KD+
Sbjct: 596 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 655
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 656 VSKMLHVDPHQR 667
>BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein.
Length = 451
Score = 240 bits (587), Expect = 6e-63
Identities = 130/362 (35%), Positives = 206/362 (56%), Gaps = 12/362 (3%)
Query: 2 ADSEIKRHINSPRGDLIQHGGYSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFER 61
A SE + + + HGG P E ++ +K + E+ ++ + FE
Sbjct: 38 AGSEDELEEGGQLNESMDHGGVGP--YELGMEHCEKF--EISETSVNRGPEKIRPECFEL 93
Query: 62 QKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVR-LKQIEHSYYEKKILCGLNFP 117
+VLG G +G VF V+ + TGK +AMK+L+K IVR K H+ E+ IL + P
Sbjct: 94 LRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHP 153
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F+V + Y F+ LY +L +++GGE+F L + G F E +A FY A++ +AL +LH
Sbjct: 154 FIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKG 213
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCK--LIRGR-TWTLCGTPEYLAPEIILSKGYGMS 234
++YRDLKPENI+++ G++K+TDFG CK + G T T CGT EY+APEI++ G+ +
Sbjct: 214 IIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRA 273
Query: 235 VDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTT 294
VDWWSLG L+++M G PPF + + +KI+ K P + + E +D++ +L+ +
Sbjct: 274 VDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAA 333
Query: 295 RRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKD 353
R G + + H +FR I+W+ +L ++ PPF P ++S D + FD F + D
Sbjct: 334 SRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVD 393
Query: 354 SP 355
SP
Sbjct: 394 SP 395
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 239 bits (584), Expect = 1e-62
Identities = 126/314 (40%), Positives = 178/314 (56%), Gaps = 8/314 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQIEHSY 105
+ A + FE KVLG G+FG VFLVK I + YAMK+L+K + +++ +
Sbjct: 58 EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTK 116
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ IL +N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A+
Sbjct: 117 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+ LAL++LH+ ++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PE++ +G+ S DWWS GVL+FEM G PF D I+ K P S E +
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ + + + R G DGV + K H +F IDW+ + IHPPF P P DT
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFY 356
Query: 343 FD-VFDEEKIKDSP 355
FD F + KDSP
Sbjct: 357 FDPEFTAKTPKDSP 370
Score = 122 bits (295), Expect = 2e-27
Identities = 81/252 (32%), Positives = 129/252 (51%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE +L P
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 475
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D Y+Y V + GGE+ + + F E A + +EYLHA +
Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D +G I+I DFGF K +R G T C T ++APE++ +GY
Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 595
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCPSHF----SVELKDI 284
+ D WSLGVLL+ M G+ PF P I +I +GK+ + S KD+
Sbjct: 596 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 655
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 656 VSKMLHVDPHQR 667
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 239 bits (584), Expect = 1e-62
Identities = 126/314 (40%), Positives = 178/314 (56%), Gaps = 8/314 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQIEHSY 105
+ A + FE KVLG G+FG VFLVK I + YAMK+L+K + +++ +
Sbjct: 57 EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTK 115
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ IL +N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A+
Sbjct: 116 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 175
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+ LAL++LH+ ++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+A
Sbjct: 176 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 235
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PE++ +G+ S DWWS GVL+FEM G PF D I+ K P S E +
Sbjct: 236 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 295
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ + + + R G DGV + K H +F IDW+ + IHPPF P P DT
Sbjct: 296 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFY 355
Query: 343 FD-VFDEEKIKDSP 355
FD F + KDSP
Sbjct: 356 FDPEFTAKTPKDSP 369
Score = 74.1 bits (174), Expect = 7e-13
Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 12/168 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE +L P
Sbjct: 421 YELKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 474
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ + + D Y+Y V+ + GGE+ + + F E A + +EYLHA +
Sbjct: 475 IITLNDVYDDGKYVY-VVTLMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 533
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIRGRTWTLCGTPEYLA 222
V+RDLKP NIL +D +G I+I DFGF K +R L TP Y A
Sbjct: 534 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLM-TPCYTA 580
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 239 bits (584), Expect = 1e-62
Identities = 126/314 (40%), Positives = 178/314 (56%), Gaps = 8/314 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQIEHSY 105
+ A + FE KVLG G+FG VFLVK I + YAMK+L+K + +++ +
Sbjct: 58 EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTK 116
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ IL +N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A+
Sbjct: 117 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+ LAL++LH+ ++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PE++ +G+ S DWWS GVL+FEM G PF D I+ K P S E +
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ + + + R G DGV + K H +F IDW+ + IHPPF P P DT
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFY 356
Query: 343 FD-VFDEEKIKDSP 355
FD F + KDSP
Sbjct: 357 FDPEFTAKTPKDSP 370
Score = 122 bits (295), Expect = 2e-27
Identities = 81/252 (32%), Positives = 129/252 (51%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE +L P
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 475
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D Y+Y V + GGE+ + + F E A + +EYLHA +
Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D +G I+I DFGF K +R G T C T ++APE++ +GY
Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 595
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCPSHF----SVELKDI 284
+ D WSLGVLL+ M G+ PF P I +I +GK+ + S KD+
Sbjct: 596 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 655
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 656 VSKMLHVDPHQR 667
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 239 bits (584), Expect = 1e-62
Identities = 126/314 (40%), Positives = 178/314 (56%), Gaps = 8/314 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQIEHSY 105
+ A + FE KVLG G+FG VFLVK I + YAMK+L+K + +++ +
Sbjct: 58 EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTK 116
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ IL +N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A+
Sbjct: 117 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+ LAL++LH+ ++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PE++ +G+ S DWWS GVL+FEM G PF D I+ K P S E +
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ + + + R G DGV + K H +F IDW+ + IHPPF P P DT
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFY 356
Query: 343 FD-VFDEEKIKDSP 355
FD F + KDSP
Sbjct: 357 FDPEFTAKTPKDSP 370
Score = 122 bits (295), Expect = 2e-27
Identities = 81/252 (32%), Positives = 129/252 (51%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE +L P
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 475
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D Y+Y V + GGE+ + + F E A + +EYLHA +
Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D +G I+I DFGF K +R G T C T ++APE++ +GY
Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 595
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCPSHF----SVELKDI 284
+ D WSLGVLL+ M G+ PF P I +I +GK+ + S KD+
Sbjct: 596 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 655
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 656 VSKMLHVDPHQR 667
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 239 bits (584), Expect = 1e-62
Identities = 126/314 (40%), Positives = 178/314 (56%), Gaps = 8/314 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQIEHSY 105
+ A + FE KVLG G+FG VFLVK I + YAMK+L+K + +++ +
Sbjct: 58 EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTK 116
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ IL +N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A+
Sbjct: 117 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+ LAL++LH+ ++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PE++ +G+ S DWWS GVL+FEM G PF D I+ K P S E +
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ + + + R G DGV + K H +F IDW+ + IHPPF P P DT
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFY 356
Query: 343 FD-VFDEEKIKDSP 355
FD F + KDSP
Sbjct: 357 FDPEFTAKTPKDSP 370
Score = 122 bits (295), Expect = 2e-27
Identities = 81/252 (32%), Positives = 129/252 (51%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE +L P
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 475
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D Y+Y V + GGE+ + + F E A + +EYLHA +
Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D +G I+I DFGF K +R G T C T ++APE++ +GY
Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 595
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCPSHF----SVELKDI 284
+ D WSLGVLL+ M G+ PF P I +I +GK+ + S KD+
Sbjct: 596 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 655
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 656 VSKMLHVDPHQR 667
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 239 bits (584), Expect = 1e-62
Identities = 126/314 (40%), Positives = 178/314 (56%), Gaps = 8/314 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQIEHSY 105
+ A + FE KVLG G+FG VFLVK I + YAMK+L+K + +++ +
Sbjct: 58 EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTK 116
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ IL +N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A+
Sbjct: 117 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 176
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+ LAL++LH+ ++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+A
Sbjct: 177 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 236
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PE++ +G+ S DWWS GVL+FEM G PF D I+ K P S E +
Sbjct: 237 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 296
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ + + + R G DGV + K H +F IDW+ + IHPPF P P DT
Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFY 356
Query: 343 FD-VFDEEKIKDSP 355
FD F + KDSP
Sbjct: 357 FDPEFTAKTPKDSP 370
Score = 122 bits (295), Expect = 2e-27
Identities = 81/252 (32%), Positives = 129/252 (51%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE +L P
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 475
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D Y+Y V + GGE+ + + F E A + +EYLHA +
Sbjct: 476 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 535
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D +G I+I DFGF K +R G T C T ++APE++ +GY
Sbjct: 536 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 595
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCPSHF----SVELKDI 284
+ D WSLGVLL+ M G+ PF P I +I +GK+ + S KD+
Sbjct: 596 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 655
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 656 VSKMLHVDPHQR 667
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 239 bits (584), Expect = 1e-62
Identities = 126/314 (40%), Positives = 178/314 (56%), Gaps = 8/314 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQIEHSY 105
+ A + FE KVLG G+FG VFLVK I + YAMK+L+K + +++ +
Sbjct: 125 EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTK 183
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ IL +N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A+
Sbjct: 184 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 243
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+ LAL++LH+ ++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+A
Sbjct: 244 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 303
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PE++ +G+ S DWWS GVL+FEM G PF D I+ K P S E +
Sbjct: 304 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 363
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ + + + R G DGV + K H +F IDW+ + IHPPF P P DT
Sbjct: 364 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFY 423
Query: 343 FD-VFDEEKIKDSP 355
FD F + KDSP
Sbjct: 424 FDPEFTAKTPKDSP 437
Score = 122 bits (295), Expect = 2e-27
Identities = 81/252 (32%), Positives = 129/252 (51%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE +L P
Sbjct: 488 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 541
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D Y+Y V + GGE+ + + F E A + +EYLHA +
Sbjct: 542 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 601
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D +G I+I DFGF K +R G T C T ++APE++ +GY
Sbjct: 602 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 661
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCPSHF----SVELKDI 284
+ D WSLGVLL+ M G+ PF P I +I +GK+ + S KD+
Sbjct: 662 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 721
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 722 VSKMLHVDPHQR 733
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 239 bits (584), Expect = 1e-62
Identities = 126/314 (40%), Positives = 178/314 (56%), Gaps = 8/314 (2%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG---KYYAMKMLEKEKIVRLKQIEHSY 105
+ A + FE KVLG G+FG VFLVK I + YAMK+L+K + +++ +
Sbjct: 44 EGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATL-KVRDRVRTK 102
Query: 106 YEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ IL +N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A+
Sbjct: 103 MERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAE 162
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLA 222
+ LAL++LH+ ++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+A
Sbjct: 163 LALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMA 222
Query: 223 PEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELK 282
PE++ +G+ S DWWS GVL+FEM G PF D I+ K P S E +
Sbjct: 223 PEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQ 282
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++ + + + R G DGV + K H +F IDW+ + IHPPF P P DT
Sbjct: 283 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFY 342
Query: 343 FD-VFDEEKIKDSP 355
FD F + KDSP
Sbjct: 343 FDPEFTAKTPKDSP 356
Score = 122 bits (295), Expect = 2e-27
Identities = 81/252 (32%), Positives = 129/252 (51%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE +L P
Sbjct: 408 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEI------LLRYGQHPN 461
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D Y+Y V + GGE+ + + F E A + +EYLHA +
Sbjct: 462 IITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGV 521
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D +G I+I DFGF K +R G T C T ++APE++ +GY
Sbjct: 522 VHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 581
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCPSHF----SVELKDI 284
+ D WSLGVLL+ M G+ PF P I +I +GK+ + S KD+
Sbjct: 582 DAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDL 641
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 642 VSKMLHVDPHQR 653
>X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha
mRNA for protein kinase C alpha. ).
Length = 672
Score = 237 bits (581), Expect = 3e-62
Identities = 123/310 (39%), Positives = 182/310 (58%), Gaps = 9/310 (2%)
Query: 45 SWDDKSESN----AKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQ 100
S D K SN KL DF VLG G+FG V L T + YA+K+L+K+ +++
Sbjct: 321 SEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDD 380
Query: 101 IEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSA 159
+E + EK++L L+ P F+ + F+ LY+V+ ++ GG++ H++++GKF+E A
Sbjct: 381 VECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQA 440
Query: 160 KFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCG 216
FY A++ + L +LH ++YRDLK +N+++D G+IKI DFG CK ++ G T T CG
Sbjct: 441 VFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCG 500
Query: 217 TPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH 276
TP+Y+APEII + YG SVDWW+ GVLL+EM AG PPF D +++ I+ P
Sbjct: 501 TPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS 560
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
S E I ++ +R G +G D + H +FR IDW+ + N I PPF PK+
Sbjct: 561 LSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG 620
Query: 337 PGDTTNFDVF 346
G NFD F
Sbjct: 621 KG-AENFDKF 629
>BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 237 bits (581), Expect = 3e-62
Identities = 123/310 (39%), Positives = 182/310 (58%), Gaps = 9/310 (2%)
Query: 45 SWDDKSESN----AKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQ 100
S D K SN KL DF VLG G+FG V L T + YA+K+L+K+ +++
Sbjct: 321 SEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDD 380
Query: 101 IEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSA 159
+E + EK++L L+ P F+ + F+ LY+V+ ++ GG++ H++++GKF+E A
Sbjct: 381 VECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQA 440
Query: 160 KFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCG 216
FY A++ + L +LH ++YRDLK +N+++D G+IKI DFG CK ++ G T T CG
Sbjct: 441 VFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCG 500
Query: 217 TPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH 276
TP+Y+APEII + YG SVDWW+ GVLL+EM AG PPF D +++ I+ P
Sbjct: 501 TPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS 560
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
S E I ++ +R G +G D + H +FR IDW+ + N I PPF PK+
Sbjct: 561 LSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG 620
Query: 337 PGDTTNFDVF 346
G NFD F
Sbjct: 621 KG-AENFDKF 629
>BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 237 bits (581), Expect = 3e-62
Identities = 123/310 (39%), Positives = 182/310 (58%), Gaps = 9/310 (2%)
Query: 45 SWDDKSESN----AKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQ 100
S D K SN KL DF VLG G+FG V L T + YA+K+L+K+ +++
Sbjct: 321 SEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDD 380
Query: 101 IEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSA 159
+E + EK++L L+ P F+ + F+ LY+V+ ++ GG++ H++++GKF+E A
Sbjct: 381 VECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQA 440
Query: 160 KFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCG 216
FY A++ + L +LH ++YRDLK +N+++D G+IKI DFG CK ++ G T T CG
Sbjct: 441 VFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCG 500
Query: 217 TPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSH 276
TP+Y+APEII + YG SVDWW+ GVLL+EM AG PPF D +++ I+ P
Sbjct: 501 TPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKS 560
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
S E I ++ +R G +G D + H +FR IDW+ + N I PPF PK+
Sbjct: 561 LSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCG 620
Query: 337 PGDTTNFDVF 346
G NFD F
Sbjct: 621 KG-AENFDKF 629
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 237 bits (579), Expect = 6e-62
Identities = 121/304 (39%), Positives = 174/304 (57%), Gaps = 8/304 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
FE KVLG G+FG VFLV+ + +G YAMK+L+K + +++ + E+ IL +N
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATL-KVRDRVRTKMERDILADVN 120
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PFVV + Y F+ LY +L F+ GG++F+ L K F E KFY A++ L L++LH+
Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKGYG 232
++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+APE++ +G+
Sbjct: 181 LGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS 240
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S DWWS GVL+FEM G PF D I+ K P S E + ++ + + +
Sbjct: 241 HSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRN 300
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEKI 351
R G+ DG + K H ++ IDW+ + I PPF P + P DT FD F
Sbjct: 301 PANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTP 360
Query: 352 KDSP 355
KDSP
Sbjct: 361 KDSP 364
Score = 120 bits (288), Expect = 1e-26
Identities = 79/249 (31%), Positives = 128/249 (51%), Gaps = 20/249 (8%)
Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVY 121
++ +G G++ H T YA+K+++K K ++IE +L P ++
Sbjct: 421 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI------LLRYGQHPNIIT 474
Query: 122 MKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYR 181
+K + D ++Y V + GGE+ + + F E A F + +EYLH+ +V+R
Sbjct: 475 LKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHR 534
Query: 182 DLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGYGMS 234
DLKP NIL +D +G ++I DFGF K +R G T C T ++APE++ +GY
Sbjct: 535 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG 594
Query: 235 VDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDIIGH 287
D WSLG+LL+ M AG+ PF + P I +I +GK+ + S KD++
Sbjct: 595 CDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSK 654
Query: 288 VLQVDTTRR 296
+L VD +R
Sbjct: 655 MLHVDPHQR 663
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 237 bits (579), Expect = 6e-62
Identities = 121/304 (39%), Positives = 174/304 (57%), Gaps = 8/304 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
FE KVLG G+FG VFLV+ + +G YAMK+L+K + +++ + E+ IL +N
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATL-KVRDRVRTKMERDILADVN 120
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PFVV + Y F+ LY +L F+ GG++F+ L K F E KFY A++ L L++LH+
Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKGYG 232
++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+APE++ +G+
Sbjct: 181 LGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS 240
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S DWWS GVL+FEM G PF D I+ K P S E + ++ + + +
Sbjct: 241 HSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRN 300
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEKI 351
R G+ DG + K H ++ IDW+ + I PPF P + P DT FD F
Sbjct: 301 PANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTP 360
Query: 352 KDSP 355
KDSP
Sbjct: 361 KDSP 364
Score = 120 bits (288), Expect = 1e-26
Identities = 79/249 (31%), Positives = 128/249 (51%), Gaps = 20/249 (8%)
Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVY 121
++ +G G++ H T YA+K+++K K ++IE +L P ++
Sbjct: 421 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI------LLRYGQHPNIIT 474
Query: 122 MKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYR 181
+K + D ++Y V + GGE+ + + F E A F + +EYLH+ +V+R
Sbjct: 475 LKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHR 534
Query: 182 DLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGYGMS 234
DLKP NIL +D +G ++I DFGF K +R G T C T ++APE++ +GY
Sbjct: 535 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG 594
Query: 235 VDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDIIGH 287
D WSLG+LL+ M AG+ PF + P I +I +GK+ + S KD++
Sbjct: 595 CDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSK 654
Query: 288 VLQVDTTRR 296
+L VD +R
Sbjct: 655 MLHVDPHQR 663
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 236 bits (578), Expect = 8e-62
Identities = 121/304 (39%), Positives = 174/304 (57%), Gaps = 8/304 (2%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
FE KVLG G+FG VFLV+ + +G YAMK+L+K + +++ + E+ IL +N
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATL-KVRDRVRTKMERDILADVN 120
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PFVV + Y F+ LY +L F+ GG++F+ L K F E KFY A++ L L++LH+
Sbjct: 121 HPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHS 180
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKGYG 232
++YRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+APE++ +G+
Sbjct: 181 LGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHS 240
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S DWWS GVL+FEM G PF D I+ K P S E + ++ + + +
Sbjct: 241 HSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRN 300
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV-FDEEKI 351
R G+ DG + K H ++ IDW+ + I PPF P + P DT FD F
Sbjct: 301 PANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREITPPFKPAVAQPDDTFYFDTEFTSRTP 360
Query: 352 KDSP 355
KDSP
Sbjct: 361 KDSP 364
Score = 120 bits (288), Expect = 1e-26
Identities = 79/249 (31%), Positives = 128/249 (51%), Gaps = 20/249 (8%)
Query: 62 QKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVVY 121
++ +G G++ H T YA+K+++K K ++IE +L P ++
Sbjct: 421 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI------LLRYGQHPNIIT 474
Query: 122 MKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYR 181
+K + D ++Y V + GGE+ + + F E A F + +EYLH+ +V+R
Sbjct: 475 LKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHR 534
Query: 182 DLKPENIL-IDRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGYGMS 234
DLKP NIL +D +G ++I DFGF K +R G T C T ++APE++ +GY
Sbjct: 535 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG 594
Query: 235 VDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDIIGH 287
D WSLG+LL+ M AG+ PF + P I +I +GK+ + S KD++
Sbjct: 595 CDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSK 654
Query: 288 VLQVDTTRR 296
+L VD +R
Sbjct: 655 MLHVDPHQR 663
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 236 bits (577), Expect = 1e-61
Identities = 124/306 (40%), Positives = 177/306 (57%), Gaps = 8/306 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG 113
+ FE KVLG G++G VFLV+ + G+ YAMK+L+K + +++ S E+ IL
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATL-KVRDRVRSKMERDILAE 115
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++L
Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 175
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKG 230
H+ ++YRDLKPENIL+D G+IKITDFG K R ++ CGT EY+APE++ +G
Sbjct: 176 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRG 235
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ S DWWS GVL+FEM G PF D I+ K P S E + ++ + +
Sbjct: 236 HTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFK 295
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
+ R G DGV + K H +F IDW+++ I PPF P + P DT +FD F
Sbjct: 296 RNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTAR 355
Query: 350 KIKDSP 355
DSP
Sbjct: 356 TPTDSP 361
Score = 122 bits (293), Expect = 3e-27
Identities = 79/252 (31%), Positives = 128/252 (50%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T YA+K+++K K ++IE +L P
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI------LLRYGQHPN 468
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D ++Y V+ + GGE+ + + F E A + ++YLH+ +
Sbjct: 469 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGV 528
Query: 179 VYRDLKPENILI-DRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL D +G I++ DFGF K +R G T C T ++APE++ +GY
Sbjct: 529 VHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGY 588
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLG+LL+ M AG PF P I +I +GKY S KD+
Sbjct: 589 DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDV 648
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 649 VSKMLHVDPHQR 660
>L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 236 bits (577), Expect = 1e-61
Identities = 116/294 (39%), Positives = 176/294 (59%), Gaps = 8/294 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
K+ DF K+LG G+FG VFL + T +++A+K L+K+ ++ +E + EK++L
Sbjct: 376 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA 435
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ +M F+ L++V+ ++ GG++ H++ KF+ + A FY A++IL L++L
Sbjct: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H+ +VYRDLK +NIL+D+ G+IKI DFG CK L +T T CGTP+Y+APEI+L +
Sbjct: 496 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWWS GVLL+EM G PF D ++ I P E KD++ +
Sbjct: 556 YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 615
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G D + H FREI+W+ + I PPF PK++SP D +NFD
Sbjct: 616 REPEKRLGVRG----DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
>L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 236 bits (577), Expect = 1e-61
Identities = 116/294 (39%), Positives = 176/294 (59%), Gaps = 8/294 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
K+ DF K+LG G+FG VFL + T +++A+K L+K+ ++ +E + EK++L
Sbjct: 376 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA 435
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ +M F+ L++V+ ++ GG++ H++ KF+ + A FY A++IL L++L
Sbjct: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H+ +VYRDLK +NIL+D+ G+IKI DFG CK L +T T CGTP+Y+APEI+L +
Sbjct: 496 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWWS GVLL+EM G PF D ++ I P E KD++ +
Sbjct: 556 YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 615
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G D + H FREI+W+ + I PPF PK++SP D +NFD
Sbjct: 616 REPEKRLGVRG----DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
>BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 236 bits (577), Expect = 1e-61
Identities = 116/294 (39%), Positives = 176/294 (59%), Gaps = 8/294 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
K+ DF K+LG G+FG VFL + T +++A+K L+K+ ++ +E + EK++L
Sbjct: 376 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA 435
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ +M F+ L++V+ ++ GG++ H++ KF+ + A FY A++IL L++L
Sbjct: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H+ +VYRDLK +NIL+D+ G+IKI DFG CK L +T T CGTP+Y+APEI+L +
Sbjct: 496 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWWS GVLL+EM G PF D ++ I P E KD++ +
Sbjct: 556 YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 615
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G D + H FREI+W+ + I PPF PK++SP D +NFD
Sbjct: 616 REPEKRLGVRG----DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
>BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 236 bits (577), Expect = 1e-61
Identities = 116/294 (39%), Positives = 176/294 (59%), Gaps = 8/294 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
K+ DF K+LG G+FG VFL + T +++A+K L+K+ ++ +E + EK++L
Sbjct: 376 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA 435
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ +M F+ L++V+ ++ GG++ H++ KF+ + A FY A++IL L++L
Sbjct: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H+ +VYRDLK +NIL+D+ G+IKI DFG CK L +T T CGTP+Y+APEI+L +
Sbjct: 496 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWWS GVLL+EM G PF D ++ I P E KD++ +
Sbjct: 556 YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 615
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G D + H FREI+W+ + I PPF PK++SP D +NFD
Sbjct: 616 REPEKRLGVRG----DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 236 bits (577), Expect = 1e-61
Identities = 124/306 (40%), Positives = 177/306 (57%), Gaps = 8/306 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG 113
+ FE KVLG G++G VFLV+ + G+ YAMK+L+K + +++ S E+ IL
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATL-KVRDRVRSKMERDILAE 115
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++L
Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 175
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKG 230
H+ ++YRDLKPENIL+D G+IKITDFG K R ++ CGT EY+APE++ +G
Sbjct: 176 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRG 235
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ S DWWS GVL+FEM G PF D I+ K P S E + ++ + +
Sbjct: 236 HTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFK 295
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
+ R G DGV + K H +F IDW+++ I PPF P + P DT +FD F
Sbjct: 296 RNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTAR 355
Query: 350 KIKDSP 355
DSP
Sbjct: 356 TPTDSP 361
Score = 122 bits (293), Expect = 3e-27
Identities = 79/252 (31%), Positives = 128/252 (50%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T YA+K+++K K ++IE +L P
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI------LLRYGQHPN 468
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D ++Y V+ + GGE+ + + F E A + ++YLH+ +
Sbjct: 469 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGV 528
Query: 179 VYRDLKPENILI-DRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL D +G I++ DFGF K +R G T C T ++APE++ +GY
Sbjct: 529 VHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGY 588
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLG+LL+ M AG PF P I +I +GKY S KD+
Sbjct: 589 DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDV 648
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 649 VSKMLHVDPHQR 660
>AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 236 bits (577), Expect = 1e-61
Identities = 116/294 (39%), Positives = 176/294 (59%), Gaps = 8/294 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
K+ DF K+LG G+FG VFL + T +++A+K L+K+ ++ +E + EK++L
Sbjct: 376 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA 435
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ +M F+ L++V+ ++ GG++ H++ KF+ + A FY A++IL L++L
Sbjct: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H+ +VYRDLK +NIL+D+ G+IKI DFG CK L +T T CGTP+Y+APEI+L +
Sbjct: 496 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWWS GVLL+EM G PF D ++ I P E KD++ +
Sbjct: 556 YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 615
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G D + H FREI+W+ + I PPF PK++SP D +NFD
Sbjct: 616 REPEKRLGVRG----DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
>AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 236 bits (577), Expect = 1e-61
Identities = 116/294 (39%), Positives = 176/294 (59%), Gaps = 8/294 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
K+ DF K+LG G+FG VFL + T +++A+K L+K+ ++ +E + EK++L
Sbjct: 148 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA 207
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ +M F+ L++V+ ++ GG++ H++ KF+ + A FY A++IL L++L
Sbjct: 208 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 267
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H+ +VYRDLK +NIL+D+ G+IKI DFG CK L +T T CGTP+Y+APEI+L +
Sbjct: 268 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 327
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWWS GVLL+EM G PF D ++ I P E KD++ +
Sbjct: 328 YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 387
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G D + H FREI+W+ + I PPF PK++SP D +NFD
Sbjct: 388 REPEKRLGVRG----DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 437
>AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 236 bits (577), Expect = 1e-61
Identities = 116/294 (39%), Positives = 176/294 (59%), Gaps = 8/294 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
K+ DF K+LG G+FG VFL + T +++A+K L+K+ ++ +E + EK++L
Sbjct: 376 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA 435
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ +M F+ L++V+ ++ GG++ H++ KF+ + A FY A++IL L++L
Sbjct: 436 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H+ +VYRDLK +NIL+D+ G+IKI DFG CK L +T T CGTP+Y+APEI+L +
Sbjct: 496 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 555
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWWS GVLL+EM G PF D ++ I P E KD++ +
Sbjct: 556 YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 615
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G D + H FREI+W+ + I PPF PK++SP D +NFD
Sbjct: 616 REPEKRLGVRG----DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 665
>AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 236 bits (577), Expect = 1e-61
Identities = 116/294 (39%), Positives = 176/294 (59%), Gaps = 8/294 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-G 113
K+ DF K+LG G+FG VFL + T +++A+K L+K+ ++ +E + EK++L
Sbjct: 148 KIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLA 207
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
PF+ +M F+ L++V+ ++ GG++ H++ KF+ + A FY A++IL L++L
Sbjct: 208 WEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 267
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYLAPEIILSKG 230
H+ +VYRDLK +NIL+D+ G+IKI DFG CK L +T T CGTP+Y+APEI+L +
Sbjct: 268 HSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQK 327
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
Y SVDWWS GVLL+EM G PF D ++ I P E KD++ +
Sbjct: 328 YNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFV 387
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +R G D + H FREI+W+ + I PPF PK++SP D +NFD
Sbjct: 388 REPEKRLGVRG----DIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFD 437
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 236 bits (577), Expect = 1e-61
Identities = 124/306 (40%), Positives = 177/306 (57%), Gaps = 8/306 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG 113
+ FE KVLG G++G VFLV+ + G+ YAMK+L+K + +++ S E+ IL
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATL-KVRDRVRSKMERDILAE 115
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++L
Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 175
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKG 230
H+ ++YRDLKPENIL+D G+IKITDFG K R ++ CGT EY+APE++ +G
Sbjct: 176 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRG 235
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ S DWWS GVL+FEM G PF D I+ K P S E + ++ + +
Sbjct: 236 HTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFK 295
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
+ R G DGV + K H +F IDW+++ I PPF P + P DT +FD F
Sbjct: 296 RNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTAR 355
Query: 350 KIKDSP 355
DSP
Sbjct: 356 TPTDSP 361
Score = 122 bits (293), Expect = 3e-27
Identities = 79/252 (31%), Positives = 128/252 (50%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T YA+K+++K K ++IE +L P
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI------LLRYGQHPN 468
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D ++Y V+ + GGE+ + + F E A + ++YLH+ +
Sbjct: 469 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGV 528
Query: 179 VYRDLKPENILI-DRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL D +G I++ DFGF K +R G T C T ++APE++ +GY
Sbjct: 529 VHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGY 588
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLG+LL+ M AG PF P I +I +GKY S KD+
Sbjct: 589 DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDV 648
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 649 VSKMLHVDPHQR 660
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 236 bits (577), Expect = 1e-61
Identities = 124/306 (40%), Positives = 177/306 (57%), Gaps = 8/306 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG 113
+ FE KVLG G++G VFLV+ + G+ YAMK+L+K + +++ S E+ IL
Sbjct: 130 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATL-KVRDRVRSKMERDILAE 188
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++L
Sbjct: 189 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 248
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKG 230
H+ ++YRDLKPENIL+D G+IKITDFG K R ++ CGT EY+APE++ +G
Sbjct: 249 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRG 308
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ S DWWS GVL+FEM G PF D I+ K P S E + ++ + +
Sbjct: 309 HTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFK 368
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
+ R G DGV + K H +F IDW+++ I PPF P + P DT +FD F
Sbjct: 369 RNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTAR 428
Query: 350 KIKDSP 355
DSP
Sbjct: 429 TPTDSP 434
Score = 122 bits (293), Expect = 3e-27
Identities = 79/252 (31%), Positives = 128/252 (50%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T YA+K+++K K ++IE +L P
Sbjct: 488 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI------LLRYGQHPN 541
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D ++Y V+ + GGE+ + + F E A + ++YLH+ +
Sbjct: 542 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGV 601
Query: 179 VYRDLKPENILI-DRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL D +G I++ DFGF K +R G T C T ++APE++ +GY
Sbjct: 602 VHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGY 661
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLG+LL+ M AG PF P I +I +GKY S KD+
Sbjct: 662 DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDV 721
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 722 VSKMLHVDPHQR 733
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 235 bits (576), Expect = 1e-61
Identities = 124/306 (40%), Positives = 177/306 (57%), Gaps = 8/306 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG 113
+ FE KVLG G++G VFLV+ + G+ YAMK+L+K + +++ S E+ IL
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATL-KVRDRVRSKMERDILAE 115
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++L
Sbjct: 116 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 175
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKG 230
H+ ++YRDLKPENIL+D G+IKITDFG K R ++ CGT EY+APE++ +G
Sbjct: 176 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRG 235
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ S DWWS GVL+FEM G PF D I+ K P S E + ++ + +
Sbjct: 236 HTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFK 295
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
+ R G DGV + K H +F IDW+++ I PPF P + P DT +FD F
Sbjct: 296 RNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPALGRPEDTFHFDPEFTAR 355
Query: 350 KIKDSP 355
DSP
Sbjct: 356 TPTDSP 361
Score = 122 bits (293), Expect = 3e-27
Identities = 79/252 (31%), Positives = 128/252 (50%), Gaps = 20/252 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T YA+K+++K K ++IE +L P
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI------LLRYGQHPN 468
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D ++Y V+ + GGE+ + + F E A + ++YLH+ +
Sbjct: 469 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGV 528
Query: 179 VYRDLKPENILI-DRTG---YIKITDFGFCKLIR---GRTWTLCGTPEYLAPEIILSKGY 231
V+RDLKP NIL D +G I++ DFGF K +R G T C T ++APE++ +GY
Sbjct: 529 VHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGY 588
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLG+LL+ M AG PF P I +I +GKY S KD+
Sbjct: 589 DAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDV 648
Query: 285 IGHVLQVDTTRR 296
+ +L VD +R
Sbjct: 649 VSKMLHVDPHQR 660
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 235 bits (576), Expect = 1e-61
Identities = 124/306 (40%), Positives = 177/306 (57%), Gaps = 8/306 (2%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCG 113
+ FE KVLG G++G VFLV+ + G+ YAMK+L+K + +++ S E+ IL
Sbjct: 58 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATL-KVRDRVRSKMERDILAE 116
Query: 114 LNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYL 173
+N PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++L
Sbjct: 117 VNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHL 176
Query: 174 HACELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKG 230
H+ ++YRDLKPENIL+D G+IKITDFG K R ++ CGT EY+APE++ +G
Sbjct: 177 HSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRG 236
Query: 231 YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQ 290
+ S DWWS GVL+FEM G PF D I+ K P S E + ++ + +
Sbjct: 237 HTQSADWWSFGVLMFEMLTGALPFQGKDRKETMSLILKAKLGMPQFLSGEAQSLLRALFK 296
Query: 291 VDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEE 349
+ R G DGV + K H +F IDW+++ I PPF P + P DT +FD F
Sbjct: 297 RNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPALGRPEDTFHFDPEFTAR 356
Query: 350 KIKDSP 355
DSP
Sbjct: 357 TPTDSP 362
Score = 62.1 bits (144), Expect = 3e-09
Identities = 36/131 (27%), Positives = 66/131 (50%), Gaps = 6/131 (4%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T YA+K++ K K ++IE +L P
Sbjct: 416 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIGKSKRDPSEEIEI------LLRYGQHPN 469
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K + D ++Y V+ + GGE+ + + F E A + ++YLH+ +
Sbjct: 470 IITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGV 529
Query: 179 VYRDLKPENIL 189
V+RDLKP NIL
Sbjct: 530 VHRDLKPSNIL 540
>L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 233 bits (569), Expect = 1e-60
Identities = 116/303 (38%), Positives = 180/303 (59%), Gaps = 10/303 (3%)
Query: 46 WDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSY 105
W+ S+ N +N+F KVLG G+FG V L + G+Y+A+K L+K+ ++ +E +
Sbjct: 338 WEGSSKCN--INNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTM 395
Query: 106 YEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGA 164
EK++L PF+ ++ F+ +L++V+ F+ GG++ H++ G+FE A FY A
Sbjct: 396 VEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAA 455
Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYL 221
+++ L++LH+ ++YRDLK +N+L+DR G+IKI DFG CK R T CGTP+Y+
Sbjct: 456 EIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYI 515
Query: 222 APEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVEL 281
APEI+ Y SVDWWS GVLL+EM G PF D ++E I P + E
Sbjct: 516 APEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKES 575
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
KDI+ + + + T+R G + K H +F+ I+W + R+ PPF PK++SP D +
Sbjct: 576 KDILEKLFEREPTKRLGVTG----NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYS 631
Query: 342 NFD 344
NFD
Sbjct: 632 NFD 634
>D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-type
protein.
Length = 626
Score = 233 bits (569), Expect = 1e-60
Identities = 116/303 (38%), Positives = 180/303 (59%), Gaps = 10/303 (3%)
Query: 46 WDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSY 105
W+ S+ N +N+F KVLG G+FG V L + G+Y+A+K L+K+ ++ +E +
Sbjct: 288 WEGSSKCN--INNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTM 345
Query: 106 YEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGA 164
EK++L PF+ ++ F+ +L++V+ F+ GG++ H++ G+FE A FY A
Sbjct: 346 VEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAA 405
Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYL 221
+++ L++LH+ ++YRDLK +N+L+DR G+IKI DFG CK R T CGTP+Y+
Sbjct: 406 EIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYI 465
Query: 222 APEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVEL 281
APEI+ Y SVDWWS GVLL+EM G PF D ++E I P + E
Sbjct: 466 APEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKES 525
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
KDI+ + + + T+R G + K H +F+ I+W + R+ PPF PK++SP D +
Sbjct: 526 KDILEKLFEREPTKRLGVTG----NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYS 581
Query: 342 NFD 344
NFD
Sbjct: 582 NFD 584
>BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta
protein.
Length = 676
Score = 233 bits (569), Expect = 1e-60
Identities = 116/303 (38%), Positives = 180/303 (59%), Gaps = 10/303 (3%)
Query: 46 WDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSY 105
W+ S+ N +N+F KVLG G+FG V L + G+Y+A+K L+K+ ++ +E +
Sbjct: 338 WEGSSKCN--INNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTM 395
Query: 106 YEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGA 164
EK++L PF+ ++ F+ +L++V+ F+ GG++ H++ G+FE A FY A
Sbjct: 396 VEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAA 455
Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYL 221
+++ L++LH+ ++YRDLK +N+L+DR G+IKI DFG CK R T CGTP+Y+
Sbjct: 456 EIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYI 515
Query: 222 APEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVEL 281
APEI+ Y SVDWWS GVLL+EM G PF D ++E I P + E
Sbjct: 516 APEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKES 575
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
KDI+ + + + T+R G + K H +F+ I+W + R+ PPF PK++SP D +
Sbjct: 576 KDILEKLFEREPTKRLGVTG----NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYS 631
Query: 342 NFD 344
NFD
Sbjct: 632 NFD 634
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 232 bits (567), Expect = 2e-60
Identities = 120/312 (38%), Positives = 190/312 (60%), Gaps = 8/312 (2%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S + +++FE +VLG G+FG V L + TG YA+K+L+K+ I++ +E + EK+
Sbjct: 346 SSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKR 405
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
IL N PF+ + F+ L++V+ F+ GG++ H++K +F+E A+FY A++I
Sbjct: 406 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIIS 465
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEI 225
AL +LH ++YRDLK +N+L+D G+ K+ DFG CK + G T T CGTP+Y+APEI
Sbjct: 466 ALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEI 525
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ YG +VDWW++GVLL+EM GH PF A + ++E I+ + P+ + I+
Sbjct: 526 LQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGIL 585
Query: 286 GHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ + T R G+L + G H +F+EIDW + + +I PPF P+I+S D +N
Sbjct: 586 KSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSN-- 643
Query: 345 VFDEEKIKDSPV 356
FD + IK+ PV
Sbjct: 644 -FDPDFIKEEPV 654
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 232 bits (567), Expect = 2e-60
Identities = 123/304 (40%), Positives = 174/304 (57%), Gaps = 10/304 (3%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
FE KVLG G+FG VFLV+ G+ YAMK+L+K + +++ + E+ IL +N
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASL-KVRDRVRTKMERDILVEVN 131
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKGYG 232
+VYRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+APE++ +G+
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S DWWS GVL+FEM G PF D I+ K P S E + ++ + + +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
R G+ +GV + K H +F IDWD + + PPF P P DT FD F +
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTP 369
Query: 352 KDSP 355
KDSP
Sbjct: 370 KDSP 373
Score = 123 bits (297), Expect = 9e-28
Identities = 80/253 (31%), Positives = 129/253 (50%), Gaps = 20/253 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE ++ P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEI------LMRYGQHPN 479
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K F D Y+Y V + GGE+ + K F E A + ++YLH +
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D + I+I DFGF K +RG L C T ++APE+++ +GY
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLGVL + M AG+ PF P I +I GK+ + S KD+
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDL 659
Query: 285 IGHVLQVDTTRRY 297
+ H+L +D +RY
Sbjct: 660 LSHMLHMDPHQRY 672
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 232 bits (567), Expect = 2e-60
Identities = 123/304 (40%), Positives = 174/304 (57%), Gaps = 10/304 (3%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
FE KVLG G+FG VFLV+ G+ YAMK+L+K + +++ + E+ IL +N
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASL-KVRDRVRTKMERDILVEVN 131
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKGYG 232
+VYRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+APE++ +G+
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S DWWS GVL+FEM G PF D I+ K P S E + ++ + + +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
R G+ +GV + K H +F IDWD + + PPF P P DT FD F +
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTP 369
Query: 352 KDSP 355
KDSP
Sbjct: 370 KDSP 373
Score = 123 bits (297), Expect = 9e-28
Identities = 80/253 (31%), Positives = 129/253 (50%), Gaps = 20/253 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE ++ P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEI------LMRYGQHPN 479
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K F D Y+Y V + GGE+ + K F E A + ++YLH +
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D + I+I DFGF K +RG L C T ++APE+++ +GY
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLGVL + M AG+ PF P I +I GK+ + S KD+
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDL 659
Query: 285 IGHVLQVDTTRRY 297
+ H+L +D +RY
Sbjct: 660 LSHMLHMDPHQRY 672
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase
protein.
Length = 745
Score = 232 bits (567), Expect = 2e-60
Identities = 123/304 (40%), Positives = 174/304 (57%), Gaps = 10/304 (3%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
FE KVLG G+FG VFLV+ G+ YAMK+L+K + +++ + E+ IL +N
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASL-KVRDRVRTKMERDILVEVN 131
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKGYG 232
+VYRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+APE++ +G+
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S DWWS GVL+FEM G PF D I+ K P S E + ++ + + +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRN 311
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
R G+ +GV + K H +F IDWD + + PPF P P DT FD F +
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTP 369
Query: 352 KDSP 355
KDSP
Sbjct: 370 KDSP 373
Score = 123 bits (297), Expect = 9e-28
Identities = 80/253 (31%), Positives = 129/253 (50%), Gaps = 20/253 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE ++ P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEI------LMRYGQHPN 479
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K F D Y+Y V + GGE+ + K F E A + ++YLH +
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D + I+I DFGF K +RG L C T ++APE+++ +GY
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLGVL + M AG+ PF P I +I GK+ + S KD+
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDL 659
Query: 285 IGHVLQVDTTRRY 297
+ H+L +D +RY
Sbjct: 660 LSHMLHMDPHQRY 672
>X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta I. ).
Length = 671
Score = 231 bits (565), Expect = 3e-60
Identities = 121/339 (35%), Positives = 194/339 (57%), Gaps = 6/339 (1%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDK-SESNAKLNDFERQKVLGTGAFGIVFLVKHIVT 81
+ AK Q ++ ++ + V +D+ + KL DF VLG G+FG V L + T
Sbjct: 305 FERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGT 364
Query: 82 GKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIA 140
+ YA+K+L+K+ +++ +E + EK++L P F+ + F+ LY+V+ ++
Sbjct: 365 DELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVN 424
Query: 141 GGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITD 200
GG++ H++++G+F+E A FY A++ + L +L + ++YRDLK +N+++D G+IKI D
Sbjct: 425 GGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIAD 484
Query: 201 FGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
FG CK + G T T CGTP+Y+APEII + YG SVDWW+ GVLL+EM AG PF
Sbjct: 485 FGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE 544
Query: 258 DPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREID 317
D +++ I+ P S E I ++ +R G +G D K H +FR ID
Sbjct: 545 DEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYID 604
Query: 318 WDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSP 355
W+ + I PP+ PK R DT+NFD F + ++ +P
Sbjct: 605 WEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTP 643
>AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (5'
partial) splice form_1 protein.
Length = 494
Score = 231 bits (565), Expect = 3e-60
Identities = 121/339 (35%), Positives = 194/339 (57%), Gaps = 6/339 (1%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDK-SESNAKLNDFERQKVLGTGAFGIVFLVKHIVT 81
+ AK Q ++ ++ + V +D+ + KL DF VLG G+FG V L + T
Sbjct: 128 FERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGT 187
Query: 82 GKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIA 140
+ YA+K+L+K+ +++ +E + EK++L P F+ + F+ LY+V+ ++
Sbjct: 188 DELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVN 247
Query: 141 GGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITD 200
GG++ H++++G+F+E A FY A++ + L +L + ++YRDLK +N+++D G+IKI D
Sbjct: 248 GGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIAD 307
Query: 201 FGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
FG CK + G T T CGTP+Y+APEII + YG SVDWW+ GVLL+EM AG PF
Sbjct: 308 FGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE 367
Query: 258 DPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREID 317
D +++ I+ P S E I ++ +R G +G D K H +FR ID
Sbjct: 368 DEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYID 427
Query: 318 WDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSP 355
W+ + I PP+ PK R DT+NFD F + ++ +P
Sbjct: 428 WEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTP 466
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 231 bits (564), Expect = 4e-60
Identities = 120/312 (38%), Positives = 189/312 (60%), Gaps = 8/312 (2%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S + +++FE +VLG G+FG V L + TG YA+K+L+K+ I+ +E + EK+
Sbjct: 345 SSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKR 404
Query: 110 ILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
IL N PF+ + F+ L++V+ F+ GG++ H++K +F+E A+FY A++I
Sbjct: 405 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIIS 464
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEI 225
AL +LH ++YRDLK +N+L+D G+ K+ DFG CK + G T T CGTP+Y+APEI
Sbjct: 465 ALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEI 524
Query: 226 ILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
+ YG +VDWW++GVLL+EM GH PF A + ++E I+ + P+ + I+
Sbjct: 525 LQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGIL 584
Query: 286 GHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ + T R G+L + G H +F+EIDW + + +I PPF P+I+S D +N
Sbjct: 585 KSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSN-- 642
Query: 345 VFDEEKIKDSPV 356
FD + IK+ PV
Sbjct: 643 -FDPDFIKEEPV 653
>CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein.
Length = 745
Score = 231 bits (564), Expect = 4e-60
Identities = 123/304 (40%), Positives = 174/304 (57%), Gaps = 10/304 (3%)
Query: 59 FERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
FE KVLG G+FG VFLV+ G+ YAMK+L+K + +++ + E+ IL +N
Sbjct: 73 FELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASL-KVRGRVRTKMERDILVEVN 131
Query: 116 FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA 175
PF+V + Y F+ LY +L F+ GG++F+ L K F E KFY A++ LAL++LH
Sbjct: 132 HPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQ 191
Query: 176 CELVYRDLKPENILIDRTGYIKITDFGFCKLI---RGRTWTLCGTPEYLAPEIILSKGYG 232
+VYRDLKPENIL+D G+IK+TDFG K + ++ CGT EY+APE++ +G+
Sbjct: 192 LGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHS 251
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S DWWS GVL+FEM G PF D I+ K P S E + ++ + + +
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQLLSAEAQSLLRMLFKRN 311
Query: 293 TTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKI 351
R G+ +GV + K H +F IDWD + + PPF P P DT FD F +
Sbjct: 312 PANRLGS--EGVEEIKRHLFFANIDWDKLYKGEVQPPFKPASGKPDDTFCFDPEFTAKTP 369
Query: 352 KDSP 355
KDSP
Sbjct: 370 KDSP 373
Score = 123 bits (297), Expect = 9e-28
Identities = 80/253 (31%), Positives = 129/253 (50%), Gaps = 20/253 (7%)
Query: 59 FERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPF 118
+E ++ +G G++ + H T +A+K+++K K ++IE ++ P
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEI------LMRYGQHPN 479
Query: 119 VVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACEL 178
++ +K F D Y+Y V + GGE+ + K F E A + ++YLH +
Sbjct: 480 IITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGV 539
Query: 179 VYRDLKPENIL-IDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGY 231
V+RDLKP NIL +D + I+I DFGF K +RG L C T ++APE+++ +GY
Sbjct: 540 VHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGY 599
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFF---ASDPMRIYEKIVAGKYRCP----SHFSVELKDI 284
+ D WSLGVL + M AG+ PF P I +I GK+ + S KD+
Sbjct: 600 DAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDL 659
Query: 285 IGHVLQVDTTRRY 297
+ H+L +D +RY
Sbjct: 660 LSHMLHMDPHQRY 672
>U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein.
Length = 984
Score = 230 bits (563), Expect = 5e-60
Identities = 119/307 (38%), Positives = 177/307 (57%), Gaps = 10/307 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF VLG G FG V L ++ T + +A+K L+K IV +++ EK+I +N
Sbjct: 654 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 713
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+L L+Y
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 772
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSK 229
LH ++VYRDLK +N+L+D G++KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 832
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW LGVL++EM G PF D +++ IV + R P S E I+ +L
Sbjct: 833 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 892
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ + RR G + D K H +FR IDW ++++ ++ PPF P IR D +N FD+E
Sbjct: 893 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSN---FDDE 949
Query: 350 KIKDSPV 356
++P+
Sbjct: 950 FTSEAPI 956
>S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein.
Length = 984
Score = 230 bits (563), Expect = 5e-60
Identities = 119/307 (38%), Positives = 177/307 (57%), Gaps = 10/307 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF VLG G FG V L ++ T + +A+K L+K IV +++ EK+I +N
Sbjct: 654 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 713
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+L L+Y
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 772
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSK 229
LH ++VYRDLK +N+L+D G++KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 832
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW LGVL++EM G PF D +++ IV + R P S E I+ +L
Sbjct: 833 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 892
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ + RR G + D K H +FR IDW ++++ ++ PPF P IR D +N FD+E
Sbjct: 893 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSN---FDDE 949
Query: 350 KIKDSPV 356
++P+
Sbjct: 950 FTSEAPI 956
>L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 230 bits (563), Expect = 5e-60
Identities = 116/303 (38%), Positives = 179/303 (59%), Gaps = 10/303 (3%)
Query: 46 WDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSY 105
W+ S+ N +N+F KVLG G+FG V L + G+Y A+K L+K+ ++ +E +
Sbjct: 338 WEGSSKCN--INNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECTM 395
Query: 106 YEKKILC-GLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGA 164
EK++L PF+ ++ F+ +L++V+ F+ GG++ H++ G+FE A FY A
Sbjct: 396 VEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAA 455
Query: 165 QVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK---LIRGRTWTLCGTPEYL 221
+++ L++LH+ ++YRDLK +N+L+DR G+IKI DFG CK R T CGTP+Y+
Sbjct: 456 EIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYI 515
Query: 222 APEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVEL 281
APEI+ Y SVDWWS GVLL+EM G PF D ++E I P + E
Sbjct: 516 APEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKES 575
Query: 282 KDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTT 341
KDI+ + + + T+R G + K H +F+ I+W + R+ PPF PK++SP D +
Sbjct: 576 KDILEKLFEREPTKRLGMTG----NIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYS 631
Query: 342 NFD 344
NFD
Sbjct: 632 NFD 634
>AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein.
Length = 984
Score = 230 bits (563), Expect = 5e-60
Identities = 119/307 (38%), Positives = 177/307 (57%), Gaps = 10/307 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF VLG G FG V L ++ T + +A+K L+K IV +++ EK+I +N
Sbjct: 654 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 713
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+L L+Y
Sbjct: 714 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 772
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSK 229
LH ++VYRDLK +N+L+D G++KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 773 LHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 832
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW LGVL++EM G PF D +++ IV + R P S E I+ +L
Sbjct: 833 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 892
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ + RR G + D K H +FR IDW ++++ ++ PPF P IR D +N FD+E
Sbjct: 893 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSN---FDDE 949
Query: 350 KIKDSPV 356
++P+
Sbjct: 950 FTSEAPI 956
>BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein.
Length = 936
Score = 229 bits (559), Expect = 2e-59
Identities = 119/307 (38%), Positives = 176/307 (57%), Gaps = 10/307 (3%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLN 115
L DF VLG G FG V L ++ T + +A+K L+K IV +++ EK+I +N
Sbjct: 606 LQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVN 665
Query: 116 ---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEY 172
PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+L L+Y
Sbjct: 666 SVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHT-DVFSEPRAVFYAACVVLGLQY 724
Query: 173 LHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSK 229
LH ++VYRDLK +N+L+D G +KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 725 LHEHKIVYRDLKLDNLLLDTEGLVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTET 784
Query: 230 GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVL 289
Y +VDWW LGVL++EM G PF D +++ IV + R P S E I+ +L
Sbjct: 785 SYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLL 844
Query: 290 QVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ + RR G + D K H +FR IDW ++++ ++ PPF P IR D +N FD+E
Sbjct: 845 RRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSN---FDDE 901
Query: 350 KIKDSPV 356
++P+
Sbjct: 902 FTSEAPI 908
>BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein.
Length = 524
Score = 229 bits (559), Expect = 2e-59
Identities = 123/307 (40%), Positives = 180/307 (58%), Gaps = 14/307 (4%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYY 106
E + +FE KVLGTGA+G VFLV+ GK YAMK+L K +V R K EH+
Sbjct: 25 EEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRT 84
Query: 107 EKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ +L PF+V + Y F+ + L+ +L +++GGEMF+HL + F+E + YG +
Sbjct: 85 ERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGE 144
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYL 221
++LALE+LH ++YRDLK EN+L+D G+I +TDFG K + RT++ CGT EY+
Sbjct: 145 IVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYM 204
Query: 222 APEIILSK-GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRC----PSH 276
APEII SK G+G +VDWWSLG+LLFE+ G PF ++ +C P
Sbjct: 205 APEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPR 264
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
+D++ +L D +R G G + +NH +F+ +DW ++ +I PF P+IRS
Sbjct: 265 IGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRS 324
Query: 337 PGDTTNF 343
D NF
Sbjct: 325 ELDVGNF 331
>BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for
IMAGE:5216639) protein.
Length = 556
Score = 229 bits (559), Expect = 2e-59
Identities = 123/307 (40%), Positives = 180/307 (58%), Gaps = 14/307 (4%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYY 106
E + +FE KVLGTGA+G VFLV+ GK YAMK+L K +V R K EH+
Sbjct: 25 EEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRT 84
Query: 107 EKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ +L PF+V + Y F+ + L+ +L +++GGEMF+HL + F+E + YG +
Sbjct: 85 ERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGE 144
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYL 221
++LALE+LH ++YRDLK EN+L+D G+I +TDFG K + RT++ CGT EY+
Sbjct: 145 IVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYM 204
Query: 222 APEIILSK-GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRC----PSH 276
APEII SK G+G +VDWWSLG+LLFE+ G PF ++ +C P
Sbjct: 205 APEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPR 264
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
+D++ +L D +R G G + +NH +F+ +DW ++ +I PF P+IRS
Sbjct: 265 IGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRS 324
Query: 337 PGDTTNF 343
D NF
Sbjct: 325 ELDVGNF 331
Score = 73.7 bits (173), Expect = 9e-13
Identities = 49/149 (32%), Positives = 77/149 (51%), Gaps = 9/149 (6%)
Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV 120
R+ LG G+F + + +G+ +A+K+L + RL+ LC + P VV
Sbjct: 413 REPALGQGSFSVCRRCRQRQSGQEFAVKILSR----RLEANTQREVAALRLCQ-SHPNVV 467
Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH-ACELV 179
+ D ++ Y VL + GGE+ H+RK F E+ A ++ A+ ++H +V
Sbjct: 468 NLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVV 527
Query: 180 YRDLKPENILI--DRTGY-IKITDFGFCK 205
+RDLKPENIL D G +KI DFGF +
Sbjct: 528 HRDLKPENILYADDTPGAPVKIIDFGFAR 556
>AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 4 isoform b variant protein.
Length = 765
Score = 229 bits (559), Expect = 2e-59
Identities = 123/307 (40%), Positives = 180/307 (58%), Gaps = 14/307 (4%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYY 106
E + +FE KVLGTGA+G VFLV+ GK YAMK+L K +V R K EH+
Sbjct: 25 EEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRT 84
Query: 107 EKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ +L PF+V + Y F+ + L+ +L +++GGEMF+HL + F+E + YG +
Sbjct: 85 ERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGE 144
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYL 221
++LALE+LH ++YRDLK EN+L+D G+I +TDFG K + RT++ CGT EY+
Sbjct: 145 IVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYM 204
Query: 222 APEIILSK-GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRC----PSH 276
APEII SK G+G +VDWWSLG+LLFE+ G PF ++ +C P
Sbjct: 205 APEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPR 264
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
+D++ +L D +R G G + +NH +F+ +DW ++ +I PF P+IRS
Sbjct: 265 IGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRS 324
Query: 337 PGDTTNF 343
D NF
Sbjct: 325 ELDVGNF 331
Score = 109 bits (263), Expect = 1e-23
Identities = 84/256 (32%), Positives = 127/256 (49%), Gaps = 26/256 (10%)
Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV 120
R+ LG G+F + + +G+ +A+K+L + RL+ LC + P VV
Sbjct: 406 REPALGQGSFSVCRRCRQRQSGQEFAVKILSR----RLEANTQREVAALRLCQ-SHPNVV 460
Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA-CELV 179
+ D + Y VL + GGE+ H+RK F E+ A ++ A+ ++H +V
Sbjct: 461 NLHEVHHDQPHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVV 520
Query: 180 YRDLKPENILI--DRTGY-IKITDFGFCKLIRGRT-----WTLCGTPEYLAPEIILSKGY 231
+RDLKPENIL D G +KI DFGF +L R ++ T C T +Y APE++ +GY
Sbjct: 521 HRDLKPENILYADDTPGAPVKIIDFGFARL-RPQSPGVPMQTPCFTLQYAAPELLAQQGY 579
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFA-------SDPMRIYEKIVAGKYRCPSH----FSVE 280
S D WSLGV+L+ M +G PF S I KI G++ S E
Sbjct: 580 DESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEE 639
Query: 281 LKDIIGHVLQVDTTRR 296
K+++ +L VD +R
Sbjct: 640 AKELVRGLLTVDPAKR 655
>AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinase B
(RSK-B) protein.
Length = 772
Score = 229 bits (559), Expect = 2e-59
Identities = 123/307 (40%), Positives = 180/307 (58%), Gaps = 14/307 (4%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYY 106
E + +FE KVLGTGA+G VFLV+ GK YAMK+L K +V R K EH+
Sbjct: 25 EEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRT 84
Query: 107 EKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ +L PF+V + Y F+ + L+ +L +++GGEMF+HL + F+E + YG +
Sbjct: 85 ERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGE 144
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYL 221
++LALE+LH ++YRDLK EN+L+D G+I +TDFG K + RT++ CGT EY+
Sbjct: 145 IVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYM 204
Query: 222 APEIILSK-GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRC----PSH 276
APEII SK G+G +VDWWSLG+LLFE+ G PF ++ +C P
Sbjct: 205 APEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPR 264
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
+D++ +L D +R G G + +NH +F+ +DW ++ +I PF P+IRS
Sbjct: 265 IGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRS 324
Query: 337 PGDTTNF 343
D NF
Sbjct: 325 ELDVGNF 331
Score = 111 bits (266), Expect = 5e-24
Identities = 84/256 (32%), Positives = 128/256 (50%), Gaps = 26/256 (10%)
Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV 120
R+ LG G+F + + +G+ +A+K+L + RL+ LC + P VV
Sbjct: 413 REPALGQGSFSVCRRCRQRQSGQEFAVKILSR----RLEANTQREVAALRLCQ-SHPNVV 467
Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA-CELV 179
+ D ++ Y VL + GGE+ H+RK F E+ A ++ A+ ++H +V
Sbjct: 468 NLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVV 527
Query: 180 YRDLKPENILI--DRTGY-IKITDFGFCKLIRGRT-----WTLCGTPEYLAPEIILSKGY 231
+RDLKPENIL D G +KI DFGF +L R ++ T C T +Y APE++ +GY
Sbjct: 528 HRDLKPENILYADDTPGAPVKIIDFGFARL-RPQSPGVPMQTPCFTLQYAAPELLAQQGY 586
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFA-------SDPMRIYEKIVAGKYRCPSH----FSVE 280
S D WSLGV+L+ M +G PF S I KI G++ S E
Sbjct: 587 DESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEE 646
Query: 281 LKDIIGHVLQVDTTRR 296
K+++ +L VD +R
Sbjct: 647 AKELVRGLLTVDPAKR 662
>AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and
stress-activated protein kinase-2 protein.
Length = 705
Score = 229 bits (559), Expect = 2e-59
Identities = 123/307 (40%), Positives = 180/307 (58%), Gaps = 14/307 (4%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYY 106
E + +FE KVLGTGA+G VFLV+ GK YAMK+L K +V R K EH+
Sbjct: 9 EEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRT 68
Query: 107 EKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
E+ +L PF+V + Y F+ + L+ +L +++GGEMF+HL + F+E + YG +
Sbjct: 69 ERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGE 128
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYL 221
++LALE+LH ++YRDLK EN+L+D G+I +TDFG K + RT++ CGT EY+
Sbjct: 129 IVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYM 188
Query: 222 APEIILSK-GYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRC----PSH 276
APEII SK G+G +VDWWSLG+LLFE+ G PF ++ +C P
Sbjct: 189 APEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPR 248
Query: 277 FSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRS 336
+D++ +L D +R G G + +NH +F+ +DW ++ +I PF P+IRS
Sbjct: 249 IGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRS 308
Query: 337 PGDTTNF 343
D NF
Sbjct: 309 ELDVGNF 315
Score = 111 bits (266), Expect = 5e-24
Identities = 84/256 (32%), Positives = 128/256 (50%), Gaps = 26/256 (10%)
Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV 120
R+ LG G+F + + +G+ +A+K+L + RL+ LC + P VV
Sbjct: 391 REPALGQGSFSVCRRCRQRQSGQEFAVKILSR----RLEANTQREVAALRLCQ-SHPNVV 445
Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHA-CELV 179
+ D ++ Y VL + GGE+ H+RK F E+ A ++ A+ ++H +V
Sbjct: 446 NLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVV 505
Query: 180 YRDLKPENILI--DRTGY-IKITDFGFCKLIRGRT-----WTLCGTPEYLAPEIILSKGY 231
+RDLKPENIL D G +KI DFGF +L R ++ T C T +Y APE++ +GY
Sbjct: 506 HRDLKPENILYADDTPGAPVKIIDFGFARL-RPQSPGVPMQTPCFTLQYAAPELLAQQGY 564
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFA-------SDPMRIYEKIVAGKYRCPSH----FSVE 280
S D WSLGV+L+ M +G PF S I KI G++ S E
Sbjct: 565 DESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEE 624
Query: 281 LKDIIGHVLQVDTTRR 296
K+++ +L VD +R
Sbjct: 625 AKELVRGLLTVDPAKR 640
>AF208004-1|AAG35720.1| 181|Homo sapiens cAMP-dependent protein
kinase catalytic subunit alpha protein.
Length = 181
Score = 227 bits (554), Expect = 6e-59
Identities = 96/171 (56%), Positives = 137/171 (80%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W+ +++ A L+ FER K LGTG+FG V LVKH TG +YAMK+L+K
Sbjct: 10 EFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDK 69
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V +++ FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 70 QKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIG 129
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGF 203
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID+ GYI++TDFGF
Sbjct: 130 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGF 180
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 226 bits (553), Expect = 8e-59
Identities = 124/348 (35%), Positives = 197/348 (56%), Gaps = 16/348 (4%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG 82
Y+P+ E Q ++ ++ K+ S+ L DF+ +V+G G++ V LV+ T
Sbjct: 210 YNPSSHESLDQVGEE-KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTD 268
Query: 83 KYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAG 141
+ YAMK+++KE + + I+ EK + N PF+V + F+ L++V+ ++ G
Sbjct: 269 RIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNG 328
Query: 142 GEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDF 201
G++ H+++ K E A+FY A++ LAL YLH ++YRDLK +N+L+D G+IK+TD+
Sbjct: 329 GDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDY 388
Query: 202 GFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF---- 254
G CK L G T T CGTP Y+APEI+ + YG SVDWW+LGVL+FEM AG PF
Sbjct: 389 GMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVG 448
Query: 255 FASDPMR-----IYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTL-KDGVLDFK 308
+ +P + +++ I+ + R P SV+ ++ L D R G L + G D +
Sbjct: 449 SSDNPDQNTEDYLFQVILEKQIRIPRSMSVKAASVLKSFLNKDPKERLGCLPQTGFADIQ 508
Query: 309 NHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSP 355
H +FR +DWD + ++ PPF P I NFD F E+++ +P
Sbjct: 509 GHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNERVQLTP 556
>U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein.
Length = 942
Score = 222 bits (543), Expect = 1e-57
Identities = 117/300 (39%), Positives = 172/300 (57%), Gaps = 7/300 (2%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+S L DF+ VLG G FG V L + +G+ +A+K L+K IV ++E EK+I
Sbjct: 607 KSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRI 666
Query: 111 LCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
L + PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+
Sbjct: 667 LAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVV 725
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPE 224
L L++LH ++VYRDLK +N+L+D GY+KI DFG CK G RT T CGTPE+LAPE
Sbjct: 726 LGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPE 785
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ Y +VDWW LGVLL+EM G PF D +++ IV + R P S E I
Sbjct: 786 VLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGI 845
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ + RR G+ + D K +FR + W+++L R+ PPF P + D +NFD
Sbjct: 846 MRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFD 905
>S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein.
Length = 942
Score = 222 bits (543), Expect = 1e-57
Identities = 117/300 (39%), Positives = 172/300 (57%), Gaps = 7/300 (2%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+S L DF+ VLG G FG V L + +G+ +A+K L+K IV ++E EK+I
Sbjct: 607 KSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRI 666
Query: 111 LCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
L + PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+
Sbjct: 667 LAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVV 725
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPE 224
L L++LH ++VYRDLK +N+L+D GY+KI DFG CK G RT T CGTPE+LAPE
Sbjct: 726 LGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPE 785
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ Y +VDWW LGVLL+EM G PF D +++ IV + R P S E I
Sbjct: 786 VLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGI 845
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ + RR G+ + D K +FR + W+++L R+ PPF P + D +NFD
Sbjct: 846 MRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFD 905
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 222 bits (543), Expect = 1e-57
Identities = 123/348 (35%), Positives = 195/348 (56%), Gaps = 16/348 (4%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG 82
Y+P+ E Q ++ ++ K+ S+ L DF+ +V+G G++ V LV+ T
Sbjct: 210 YNPSSHESLDQVGEE-KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTD 268
Query: 83 KYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAG 141
+ YAMK+++KE + + I+ EK + N PF+V + F+ L++V+ ++ G
Sbjct: 269 RIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNG 328
Query: 142 GEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDF 201
G++ H+++ K E A+FY A++ LAL YLH ++YRDLK +N+L+D G+IK+TD+
Sbjct: 329 GDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDY 388
Query: 202 GFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF---- 254
G CK L G T T CGTP Y+APEI+ + YG SVDWW+LGVL+FEM AG PF
Sbjct: 389 GMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVG 448
Query: 255 FASDPMR-----IYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGT-LKDGVLDFK 308
+ +P + +++ I+ + R P SV+ ++ L D R G + G D +
Sbjct: 449 SSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQ 508
Query: 309 NHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSP 355
H +FR +DWD + ++ PPF P I NFD F E ++ +P
Sbjct: 509 GHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTP 556
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 222 bits (543), Expect = 1e-57
Identities = 123/348 (35%), Positives = 195/348 (56%), Gaps = 16/348 (4%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTG 82
Y+P+ E Q ++ ++ K+ S+ L DF+ +V+G G++ V LV+ T
Sbjct: 210 YNPSSHESLDQVGEE-KEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTD 268
Query: 83 KYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGLNFPFVVYMKYYFKDNVYLYYVLPFIAG 141
+ YAMK+++KE + + I+ EK + N PF+V + F+ L++V+ ++ G
Sbjct: 269 RIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNG 328
Query: 142 GEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDF 201
G++ H+++ K E A+FY A++ LAL YLH ++YRDLK +N+L+D G+IK+TD+
Sbjct: 329 GDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDY 388
Query: 202 GFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPF---- 254
G CK L G T T CGTP Y+APEI+ + YG SVDWW+LGVL+FEM AG PF
Sbjct: 389 GMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVG 448
Query: 255 FASDPMR-----IYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGT-LKDGVLDFK 308
+ +P + +++ I+ + R P SV+ ++ L D R G + G D +
Sbjct: 449 SSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQ 508
Query: 309 NHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD-VFDEEKIKDSP 355
H +FR +DWD + ++ PPF P I NFD F E ++ +P
Sbjct: 509 GHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTP 556
>D26181-1|BAA05169.1| 942|Homo sapiens PKN protein.
Length = 942
Score = 222 bits (543), Expect = 1e-57
Identities = 117/300 (39%), Positives = 172/300 (57%), Gaps = 7/300 (2%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+S L DF+ VLG G FG V L + +G+ +A+K L+K IV ++E EK+I
Sbjct: 607 KSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRI 666
Query: 111 LCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
L + PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+
Sbjct: 667 LAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVV 725
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPE 224
L L++LH ++VYRDLK +N+L+D GY+KI DFG CK G RT T CGTPE+LAPE
Sbjct: 726 LGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPE 785
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ Y +VDWW LGVLL+EM G PF D +++ IV + R P S E I
Sbjct: 786 VLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGI 845
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ + RR G+ + D K +FR + W+++L R+ PPF P + D +NFD
Sbjct: 846 MRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFD 905
>BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein.
Length = 942
Score = 222 bits (542), Expect = 2e-57
Identities = 117/300 (39%), Positives = 172/300 (57%), Gaps = 7/300 (2%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+S L DF+ VLG G FG V L + +G+ +A+K L+K IV ++E EK+I
Sbjct: 607 KSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRI 666
Query: 111 LCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
L + PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+
Sbjct: 667 LAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHS-DVFSEPRAIFYSACVV 725
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPE 224
L L++LH ++VYRDLK +N+L+D GY+KI DFG CK G RT T CGTPE+LAPE
Sbjct: 726 LGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPE 785
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ Y +VDWW LGVLL+EM G PF D +++ IV + R P S E I
Sbjct: 786 VLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGI 845
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ + RR G+ + D K +FR + W+++L R+ PPF P + D +NFD
Sbjct: 846 MRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDISNFD 905
>AL450063-5|CAI16848.1| 186|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 186
Score = 221 bits (540), Expect = 3e-57
Identities = 94/165 (56%), Positives = 133/165 (80%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 22 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 81
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 82 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 141
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIK 197
+F E A+FY AQ++L EYLH+ +L+YRDLKPEN+LID GYI+
Sbjct: 142 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQ 186
>X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta II. ).
Length = 673
Score = 220 bits (537), Expect = 7e-57
Identities = 117/329 (35%), Positives = 186/329 (56%), Gaps = 6/329 (1%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDK-SESNAKLNDFERQKVLGTGAFGIVFLVKHIVT 81
+ AK Q ++ ++ + V +D+ + KL DF VLG G+FG V L + T
Sbjct: 305 FERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGT 364
Query: 82 GKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIA 140
+ YA+K+L+K+ +++ +E + EK++L P F+ + F+ LY+V+ ++
Sbjct: 365 DELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVN 424
Query: 141 GGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITD 200
GG++ H++++G+F+E A FY A++ + L +L + ++YRDLK +N+++D G+IKI D
Sbjct: 425 GGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIAD 484
Query: 201 FGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
FG CK + G T T CGTP+Y+APEII + YG SVDWW+ GVLL+EM AG PF
Sbjct: 485 FGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE 544
Query: 258 DPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREID 317
D +++ I+ P S E I ++ +R G +G D K H +FR ID
Sbjct: 545 DEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYID 604
Query: 318 WDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
W+ + I PP+ PK + NFD F
Sbjct: 605 WEKLERKEIQPPYKPK-ACGRNAENFDRF 632
>M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II
type protein.
Length = 673
Score = 220 bits (537), Expect = 7e-57
Identities = 117/329 (35%), Positives = 186/329 (56%), Gaps = 6/329 (1%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDK-SESNAKLNDFERQKVLGTGAFGIVFLVKHIVT 81
+ AK Q ++ ++ + V +D+ + KL DF VLG G+FG V L + T
Sbjct: 305 FERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGT 364
Query: 82 GKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIA 140
+ YA+K+L+K+ +++ +E + EK++L P F+ + F+ LY+V+ ++
Sbjct: 365 DELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVN 424
Query: 141 GGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITD 200
GG++ H++++G+F+E A FY A++ + L +L + ++YRDLK +N+++D G+IKI D
Sbjct: 425 GGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIAD 484
Query: 201 FGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
FG CK + G T T CGTP+Y+APEII + YG SVDWW+ GVLL+EM AG PF
Sbjct: 485 FGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE 544
Query: 258 DPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREID 317
D +++ I+ P S E I ++ +R G +G D K H +FR ID
Sbjct: 545 DEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYID 604
Query: 318 WDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
W+ + I PP+ PK + NFD F
Sbjct: 605 WEKLERKEIQPPYKPK-ACGRNAENFDRF 632
>BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta 1
protein.
Length = 673
Score = 220 bits (537), Expect = 7e-57
Identities = 117/329 (35%), Positives = 186/329 (56%), Gaps = 6/329 (1%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDK-SESNAKLNDFERQKVLGTGAFGIVFLVKHIVT 81
+ AK Q ++ ++ + V +D+ + KL DF VLG G+FG V L + T
Sbjct: 305 FERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGT 364
Query: 82 GKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIA 140
+ YA+K+L+K+ +++ +E + EK++L P F+ + F+ LY+V+ ++
Sbjct: 365 DELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVN 424
Query: 141 GGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITD 200
GG++ H++++G+F+E A FY A++ + L +L + ++YRDLK +N+++D G+IKI D
Sbjct: 425 GGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIAD 484
Query: 201 FGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
FG CK + G T T CGTP+Y+APEII + YG SVDWW+ GVLL+EM AG PF
Sbjct: 485 FGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE 544
Query: 258 DPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREID 317
D +++ I+ P S E I ++ +R G +G D K H +FR ID
Sbjct: 545 DEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYID 604
Query: 318 WDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
W+ + I PP+ PK + NFD F
Sbjct: 605 WEKLERKEIQPPYKPK-ACGRNAENFDRF 632
>AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (5'
partial) splice form_ protein.
Length = 496
Score = 220 bits (537), Expect = 7e-57
Identities = 117/329 (35%), Positives = 186/329 (56%), Gaps = 6/329 (1%)
Query: 23 YSPAKQEQYSQYLKKLRQDFVESWDDK-SESNAKLNDFERQKVLGTGAFGIVFLVKHIVT 81
+ AK Q ++ ++ + V +D+ + KL DF VLG G+FG V L + T
Sbjct: 128 FERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGT 187
Query: 82 GKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP-FVVYMKYYFKDNVYLYYVLPFIA 140
+ YA+K+L+K+ +++ +E + EK++L P F+ + F+ LY+V+ ++
Sbjct: 188 DELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVN 247
Query: 141 GGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITD 200
GG++ H++++G+F+E A FY A++ + L +L + ++YRDLK +N+++D G+IKI D
Sbjct: 248 GGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIAD 307
Query: 201 FGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFAS 257
FG CK + G T T CGTP+Y+APEII + YG SVDWW+ GVLL+EM AG PF
Sbjct: 308 FGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGE 367
Query: 258 DPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREID 317
D +++ I+ P S E I ++ +R G +G D K H +FR ID
Sbjct: 368 DEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYID 427
Query: 318 WDSILNSRIHPPFFPKIRSPGDTTNFDVF 346
W+ + I PP+ PK + NFD F
Sbjct: 428 WEKLERKEIQPPYKPK-ACGRNAENFDRF 455
>X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein
kinase protein.
Length = 479
Score = 219 bits (536), Expect = 1e-56
Identities = 116/300 (38%), Positives = 171/300 (57%), Gaps = 7/300 (2%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
+S L DF+ VLG G FG V L + +G+ +A+K L+K IV ++E EK+I
Sbjct: 144 KSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRI 203
Query: 111 LCGLN---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVI 167
L + PF+V + F+ ++ +V+ + AGG++ H+ F E A FY A V+
Sbjct: 204 LAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLILHIHS-DVFSEPRAIFYSACVV 262
Query: 168 LALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPE 224
L L++LH ++VYRDLK +N+L+D GY+KI DFG CK G RT T CGTPE+LAPE
Sbjct: 263 LGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPE 322
Query: 225 IILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDI 284
++ Y +VDWW LGVLL+EM G P D +++ IV + R P S E I
Sbjct: 323 VLTDTSYTRAVDWWGLGVLLYEMLVGESPLPGDDEEEVFDSIVNDEVRYPRFLSAEAIGI 382
Query: 285 IGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
+ +L+ + RR G+ + D K +FR + W+++L R+ PPF P + D +NFD
Sbjct: 383 MRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDISNFD 442
>BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 5 protein.
Length = 549
Score = 218 bits (533), Expect = 2e-56
Identities = 122/319 (38%), Positives = 183/319 (57%), Gaps = 16/319 (5%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYYEKKIL 111
+ +FE KVLGTGA+G VFLV+ I TGK YAMK+L+K IV + K EH+ E+++L
Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105
Query: 112 CGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ PF+V + Y F+ L+ +L +I GGE+F+HL + +F E + Y +++LAL
Sbjct: 106 EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 165
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYLAPEII 226
E+LH ++YRD+K ENIL+D G++ +TDFG K R ++ CGT EY+AP+I+
Sbjct: 166 EHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIV 225
Query: 227 L--SKGYGMSVDWWSLGVLLFEMSAGHPPFFA----SDPMRIYEKIVAGKYRCPSHFSVE 280
G+ +VDWWSLGVL++E+ G PF + I +I+ + P S
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSAL 285
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
KD+I +L D +R G + K H +F++I+WD + ++ PF P IR D
Sbjct: 286 AKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDV 345
Query: 341 TNF-DVFDEEKIKDSPVCL 358
+NF + F E SP L
Sbjct: 346 SNFAEEFTEMDPTYSPAAL 364
Score = 64.5 bits (150), Expect = 6e-10
Identities = 36/126 (28%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV 120
+ K LG G+F I H + + +A+K++ K R++ LC P +V
Sbjct: 428 KDKPLGEGSFSICRKCVHKKSNQAFAVKIISK----RMEANTQKEITALKLCE-GHPNIV 482
Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVY 180
+ F D ++ + V+ + GGE+F ++K F ET A + +++ A+ ++H +V+
Sbjct: 483 KLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVH 542
Query: 181 RDLKPE 186
RDLKPE
Sbjct: 543 RDLKPE 548
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 218 bits (533), Expect = 2e-56
Identities = 122/319 (38%), Positives = 183/319 (57%), Gaps = 16/319 (5%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYYEKKIL 111
+ +FE KVLGTGA+G VFLV+ I TGK YAMK+L+K IV + K EH+ E+++L
Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105
Query: 112 CGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ PF+V + Y F+ L+ +L +I GGE+F+HL + +F E + Y +++LAL
Sbjct: 106 EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 165
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYLAPEII 226
E+LH ++YRD+K ENIL+D G++ +TDFG K R ++ CGT EY+AP+I+
Sbjct: 166 EHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIV 225
Query: 227 L--SKGYGMSVDWWSLGVLLFEMSAGHPPFFA----SDPMRIYEKIVAGKYRCPSHFSVE 280
G+ +VDWWSLGVL++E+ G PF + I +I+ + P S
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSAL 285
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
KD+I +L D +R G + K H +F++I+WD + ++ PF P IR D
Sbjct: 286 AKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDV 345
Query: 341 TNF-DVFDEEKIKDSPVCL 358
+NF + F E SP L
Sbjct: 346 SNFAEEFTEMDPTYSPAAL 364
Score = 110 bits (265), Expect = 7e-24
Identities = 81/253 (32%), Positives = 121/253 (47%), Gaps = 22/253 (8%)
Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV 120
+ K LG G+F I H + + +K++ K R++ LC P +V
Sbjct: 428 KDKPLGEGSFSICRKCVHKKSNQALQVKIISK----RMEANTQKEITALKLCE-GHPNIV 482
Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVY 180
+ F D ++ + V+ + GGE+F LRK F ET A + +++ AL ++H +V+
Sbjct: 483 KLHEVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVH 542
Query: 181 RDLKPENILIDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGYGMS 234
RDLKPEN+L IKI DFGF +L L C T PE++ GY S
Sbjct: 543 RDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHSCRPELLNQNGYDES 602
Query: 235 VDWWSLGVLLFEMSAGHPPFFASD-------PMRIYEKIVAGKY----RCPSHFSVELKD 283
D WSLGV+L+ M +G PF + D + I +KI G + + S E KD
Sbjct: 603 CDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKD 662
Query: 284 IIGHVLQVDTTRR 296
+I +L VD +R
Sbjct: 663 LIQGLLTVDPNKR 675
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 218 bits (533), Expect = 2e-56
Identities = 122/319 (38%), Positives = 183/319 (57%), Gaps = 16/319 (5%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYYEKKIL 111
+ +FE KVLGTGA+G VFLV+ I TGK YAMK+L+K IV + K EH+ E+++L
Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105
Query: 112 CGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ PF+V + Y F+ L+ +L +I GGE+F+HL + +F E + Y +++LAL
Sbjct: 106 EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 165
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYLAPEII 226
E+LH ++YRD+K ENIL+D G++ +TDFG K R ++ CGT EY+AP+I+
Sbjct: 166 EHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIV 225
Query: 227 L--SKGYGMSVDWWSLGVLLFEMSAGHPPFFA----SDPMRIYEKIVAGKYRCPSHFSVE 280
G+ +VDWWSLGVL++E+ G PF + I +I+ + P S
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSAL 285
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
KD+I +L D +R G + K H +F++I+WD + ++ PF P IR D
Sbjct: 286 AKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDV 345
Query: 341 TNF-DVFDEEKIKDSPVCL 358
+NF + F E SP L
Sbjct: 346 SNFAEEFTEMDPTYSPAAL 364
Score = 117 bits (282), Expect = 6e-26
Identities = 81/253 (32%), Positives = 125/253 (49%), Gaps = 22/253 (8%)
Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV 120
+ K LG G+F I H + + +A+K++ K R++ LC P +V
Sbjct: 428 KDKPLGEGSFSICRKCVHKKSNQAFAVKIISK----RMEANTQKEITALKLCE-GHPNIV 482
Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVY 180
+ F D ++ + V+ + GGE+F ++K F ET A + +++ A+ ++H +V+
Sbjct: 483 KLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVH 542
Query: 181 RDLKPENILIDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGYGMS 234
RDLKPEN+L IKI DFGF +L L C T Y APE++ GY S
Sbjct: 543 RDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDES 602
Query: 235 VDWWSLGVLLFEMSAGHPPFFASD-------PMRIYEKIVAGKY----RCPSHFSVELKD 283
D WSLGV+L+ M +G PF + D + I +KI G + + S E KD
Sbjct: 603 CDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKD 662
Query: 284 IIGHVLQVDTTRR 296
+I +L VD +R
Sbjct: 663 LIQGLLTVDPNKR 675
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 218 bits (533), Expect = 2e-56
Identities = 122/319 (38%), Positives = 183/319 (57%), Gaps = 16/319 (5%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIV---TGKYYAMKMLEKEKIV-RLKQIEHSYYEKKIL 111
+ +FE KVLGTGA+G VFLV+ I TGK YAMK+L+K IV + K EH+ E+++L
Sbjct: 46 IENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVL 105
Query: 112 CGLN-FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILAL 170
+ PF+V + Y F+ L+ +L +I GGE+F+HL + +F E + Y +++LAL
Sbjct: 106 EHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLAL 165
Query: 171 EYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLI----RGRTWTLCGTPEYLAPEII 226
E+LH ++YRD+K ENIL+D G++ +TDFG K R ++ CGT EY+AP+I+
Sbjct: 166 EHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIV 225
Query: 227 L--SKGYGMSVDWWSLGVLLFEMSAGHPPFFA----SDPMRIYEKIVAGKYRCPSHFSVE 280
G+ +VDWWSLGVL++E+ G PF + I +I+ + P S
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSAL 285
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
KD+I +L D +R G + K H +F++I+WD + ++ PF P IR D
Sbjct: 286 AKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDV 345
Query: 341 TNF-DVFDEEKIKDSPVCL 358
+NF + F E SP L
Sbjct: 346 SNFAEEFTEMDPTYSPAAL 364
Score = 117 bits (282), Expect = 6e-26
Identities = 81/253 (32%), Positives = 125/253 (49%), Gaps = 22/253 (8%)
Query: 61 RQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFPFVV 120
+ K LG G+F I H + + +A+K++ K R++ LC P +V
Sbjct: 428 KDKPLGEGSFSICRKCVHKKSNQAFAVKIISK----RMEANTQKEITALKLCE-GHPNIV 482
Query: 121 YMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACELVY 180
+ F D ++ + V+ + GGE+F ++K F ET A + +++ A+ ++H +V+
Sbjct: 483 KLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVH 542
Query: 181 RDLKPENILIDRTG---YIKITDFGFCKLIRGRTWTL---CGTPEYLAPEIILSKGYGMS 234
RDLKPEN+L IKI DFGF +L L C T Y APE++ GY S
Sbjct: 543 RDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDES 602
Query: 235 VDWWSLGVLLFEMSAGHPPFFASD-------PMRIYEKIVAGKY----RCPSHFSVELKD 283
D WSLGV+L+ M +G PF + D + I +KI G + + S E KD
Sbjct: 603 CDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKD 662
Query: 284 IIGHVLQVDTTRR 296
+I +L VD +R
Sbjct: 663 LIQGLLTVDPNKR 675
>X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon
protein.
Length = 737
Score = 217 bits (531), Expect = 4e-56
Identities = 114/313 (36%), Positives = 185/313 (59%), Gaps = 9/313 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GL 114
L++F KVLG G+FG V L + + YA+K+L+K+ I++ ++ + EK+IL
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
P++ + F+ L++V+ ++ GG++ +++ KF+E ++FY A+V AL +LH
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +NIL+D G+ K+ DFG CK ++ G T T CGTP+Y+APEI+ Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G SVDWW+LGVL++EM AG PPF A + ++E I+ P S E I+ +
Sbjct: 585 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 644
Query: 292 DTTRRYGTL--KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ +R G + ++G K H +F+EIDW + +I PPF P+I++ D N FD++
Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNN---FDQD 701
Query: 350 KIKDSPVCLYEEE 362
++ PV +E
Sbjct: 702 FTREEPVLTLVDE 714
>BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 217 bits (531), Expect = 4e-56
Identities = 114/313 (36%), Positives = 185/313 (59%), Gaps = 9/313 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GL 114
L++F KVLG G+FG V L + + YA+K+L+K+ I++ ++ + EK+IL
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
P++ + F+ L++V+ ++ GG++ +++ KF+E ++FY A+V AL +LH
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +NIL+D G+ K+ DFG CK ++ G T T CGTP+Y+APEI+ Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G SVDWW+LGVL++EM AG PPF A + ++E I+ P S E I+ +
Sbjct: 585 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 644
Query: 292 DTTRRYGTL--KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ +R G + ++G K H +F+EIDW + +I PPF P+I++ D N FD++
Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNN---FDQD 701
Query: 350 KIKDSPVCLYEEE 362
++ PV +E
Sbjct: 702 FTREEPVLTLVDE 714
>BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 217 bits (531), Expect = 4e-56
Identities = 114/313 (36%), Positives = 185/313 (59%), Gaps = 9/313 (2%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILC-GL 114
L++F KVLG G+FG V L + + YA+K+L+K+ I++ ++ + EK+IL
Sbjct: 405 LDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALAR 464
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
P++ + F+ L++V+ ++ GG++ +++ KF+E ++FY A+V AL +LH
Sbjct: 465 KHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLH 524
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRG-RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +NIL+D G+ K+ DFG CK ++ G T T CGTP+Y+APEI+ Y
Sbjct: 525 QHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEY 584
Query: 232 GMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQV 291
G SVDWW+LGVL++EM AG PPF A + ++E I+ P S E I+ +
Sbjct: 585 GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTK 644
Query: 292 DTTRRYGTL--KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDVFDEE 349
+ +R G + ++G K H +F+EIDW + +I PPF P+I++ D N FD++
Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNN---FDQD 701
Query: 350 KIKDSPVCLYEEE 362
++ PV +E
Sbjct: 702 FTREEPVLTLVDE 714
>Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma
protein.
Length = 536
Score = 215 bits (526), Expect = 2e-55
Identities = 117/306 (38%), Positives = 174/306 (56%), Gaps = 10/306 (3%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S ++DF VLG G+FG V L + + + YA+K+L+K+ IV+ ++ + EK+
Sbjct: 181 SPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKR 240
Query: 110 ILC-GLNFP-----FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYG 163
+L G P F+ + F+ LY+V+ ++ GG++ H++++GKF+E A FY
Sbjct: 241 VLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYA 300
Query: 164 AQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEY 220
A++ + L +LH ++YRDLK +N+++D G+IKITDFG CK + G T T CGTP+Y
Sbjct: 301 AEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDY 360
Query: 221 LAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVE 280
+APEII + YG SVDWWS GVLL+EM AG PPF D +++ I+ P S E
Sbjct: 361 IAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSRE 420
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
I L +R G+ DG + H +FR IDW+ + I PPF P+
Sbjct: 421 AVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPR-PCGRSG 479
Query: 341 TNFDVF 346
NFD F
Sbjct: 480 ENFDKF 485
>BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma
protein.
Length = 697
Score = 215 bits (526), Expect = 2e-55
Identities = 117/306 (38%), Positives = 174/306 (56%), Gaps = 10/306 (3%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S ++DF VLG G+FG V L + + + YA+K+L+K+ IV+ ++ + EK+
Sbjct: 342 SPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKR 401
Query: 110 ILC-GLNFP-----FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYG 163
+L G P F+ + F+ LY+V+ ++ GG++ H++++GKF+E A FY
Sbjct: 402 VLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYA 461
Query: 164 AQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEY 220
A++ + L +LH ++YRDLK +N+++D G+IKITDFG CK + G T T CGTP+Y
Sbjct: 462 AEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDY 521
Query: 221 LAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVE 280
+APEII + YG SVDWWS GVLL+EM AG PPF D +++ I+ P S E
Sbjct: 522 IAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSRE 581
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
I L +R G+ DG + H +FR IDW+ + I PPF P+
Sbjct: 582 AVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPR-PCGRSG 640
Query: 341 TNFDVF 346
NFD F
Sbjct: 641 ENFDKF 646
>AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma
protein.
Length = 697
Score = 215 bits (526), Expect = 2e-55
Identities = 117/306 (38%), Positives = 174/306 (56%), Gaps = 10/306 (3%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S ++DF VLG G+FG V L + + + YA+K+L+K+ IV+ ++ + EK+
Sbjct: 342 SPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKR 401
Query: 110 ILC-GLNFP-----FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYG 163
+L G P F+ + F+ LY+V+ ++ GG++ H++++GKF+E A FY
Sbjct: 402 VLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYA 461
Query: 164 AQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEY 220
A++ + L +LH ++YRDLK +N+++D G+IKITDFG CK + G T T CGTP+Y
Sbjct: 462 AEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDY 521
Query: 221 LAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVE 280
+APEII + YG SVDWWS GVLL+EM AG PPF D +++ I+ P S E
Sbjct: 522 IAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSRE 581
Query: 281 LKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDT 340
I L +R G+ DG + H +FR IDW+ + I PPF P+
Sbjct: 582 AVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPR-PCGRSG 640
Query: 341 TNFDVF 346
NFD F
Sbjct: 641 ENFDKF 646
>AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta
protein.
Length = 889
Score = 215 bits (525), Expect = 2e-55
Identities = 113/296 (38%), Positives = 170/296 (57%), Gaps = 7/296 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L DF VLG G FG V LV+ TGKYYA+K L+K++++ +IE Y EK+IL +
Sbjct: 555 RLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAV 614
Query: 115 N---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
PF++ + F+ + + +V F+ GG++ + + F E A+FY A V+L L+
Sbjct: 615 GCTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLMMQIHE-DVFPEPQARFYVACVVLGLQ 673
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILS 228
+LH +++YRDLK +N+L+D G++KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 674 FLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQ 733
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW+LGVLL+EM G PF +++ IV P SV+ + I +
Sbjct: 734 EAYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKL 793
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
LQ +R G + + K +FR +W ++L I PPF P + P D F+
Sbjct: 794 LQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFE 849
>BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 214 bits (522), Expect = 5e-55
Identities = 113/296 (38%), Positives = 169/296 (57%), Gaps = 7/296 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L DF VLG G FG V LV+ TGKYYA+K L+K++++ +IE Y EK+IL +
Sbjct: 555 RLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAV 614
Query: 115 N---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
PF++ + F+ + + +V F+ GG++ + + F E A+FY A V+L L+
Sbjct: 615 GCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE-DVFPEPQARFYVACVVLGLQ 673
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILS 228
+LH +++YRDLK +N+L+D G++KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 674 FLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQ 733
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LGVLL+EM G PF +++ IV P SV+ + I +
Sbjct: 734 EAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKL 793
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
LQ +R G + + K +FR +W ++L I PPF P + P D F+
Sbjct: 794 LQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFE 849
>AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 214 bits (522), Expect = 5e-55
Identities = 113/296 (38%), Positives = 169/296 (57%), Gaps = 7/296 (2%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
+L DF VLG G FG V LV+ TGKYYA+K L+K++++ +IE Y EK+IL +
Sbjct: 555 RLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAV 614
Query: 115 N---FPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
PF++ + F+ + + +V F+ GG++ + + F E A+FY A V+L L+
Sbjct: 615 GCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHE-DVFPEPQARFYVACVVLGLQ 673
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILS 228
+LH +++YRDLK +N+L+D G++KI DFG CK G RT T CGTPE+LAPE++
Sbjct: 674 FLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQ 733
Query: 229 KGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHV 288
+ Y +VDWW LGVLL+EM G PF +++ IV P SV+ + I +
Sbjct: 734 EAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKL 793
Query: 289 LQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFD 344
LQ +R G + + K +FR +W ++L I PPF P + P D F+
Sbjct: 794 LQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFE 849
>BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for
IMAGE:5496641) protein.
Length = 344
Score = 210 bits (514), Expect = 4e-54
Identities = 95/202 (47%), Positives = 138/202 (68%), Gaps = 3/202 (1%)
Query: 49 KSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEK 108
K+ + +NDF+ K+LG G FG V LV+ TG+YYAMK+L KE I+ ++ H+ E
Sbjct: 142 KARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTES 201
Query: 109 KILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVIL 168
++L PF+ +KY F+ + L +V+ + GGE+F HL + F E A+FYGA+++
Sbjct: 202 RVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVS 261
Query: 169 ALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCK--LIRGRTW-TLCGTPEYLAPEI 225
ALEYLH+ ++VYRD+K EN+++D+ G+IKITDFG CK + G T T CGTPEYLAPE+
Sbjct: 262 ALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEV 321
Query: 226 ILSKGYGMSVDWWSLGVLLFEM 247
+ YG +VDWW LGV+++EM
Sbjct: 322 LEDNDYGRAVDWWGLGVVMYEM 343
>Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta
protein.
Length = 584
Score = 210 bits (513), Expect = 6e-54
Identities = 114/313 (36%), Positives = 176/313 (56%), Gaps = 13/313 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGL 114
L DF+ +V+G G++ V LV+ + YAMK+++KE + + I+ EK +
Sbjct: 241 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 300
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L+ V+ ++ GG++ H+++ K E A+FY A++ +AL +LH
Sbjct: 301 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 360
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+TD+G CK G T T CGTP Y+APEI+ + Y
Sbjct: 361 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 420
Query: 232 GMSVDWWSLGVLLFEMSAGHPPF--FASDPMR-----IYEKIVAGKYRCPSHFSVELKDI 284
G SVDWW+LGVL+FEM AG PF +P +++ I+ R P SV+ +
Sbjct: 421 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 480
Query: 285 IGHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ L D R G + G D K+H +FR IDWD + + PPF P+I NF
Sbjct: 481 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 540
Query: 344 DV-FDEEKIKDSP 355
D F E ++ +P
Sbjct: 541 DTQFTSEPVQLTP 553
>BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (513), Expect = 6e-54
Identities = 114/313 (36%), Positives = 176/313 (56%), Gaps = 13/313 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGL 114
L DF+ +V+G G++ V LV+ + YAMK+++KE + + I+ EK +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L+ V+ ++ GG++ H+++ K E A+FY A++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+TD+G CK G T T CGTP Y+APEI+ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 232 GMSVDWWSLGVLLFEMSAGHPPF--FASDPMR-----IYEKIVAGKYRCPSHFSVELKDI 284
G SVDWW+LGVL+FEM AG PF +P +++ I+ R P SV+ +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 285 IGHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ L D R G + G D K+H +FR IDWD + + PPF P+I NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 344 DV-FDEEKIKDSP 355
D F E ++ +P
Sbjct: 549 DTQFTSEPVQLTP 561
>BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (513), Expect = 6e-54
Identities = 114/313 (36%), Positives = 176/313 (56%), Gaps = 13/313 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGL 114
L DF+ +V+G G++ V LV+ + YAMK+++KE + + I+ EK +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L+ V+ ++ GG++ H+++ K E A+FY A++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+TD+G CK G T T CGTP Y+APEI+ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 232 GMSVDWWSLGVLLFEMSAGHPPF--FASDPMR-----IYEKIVAGKYRCPSHFSVELKDI 284
G SVDWW+LGVL+FEM AG PF +P +++ I+ R P SV+ +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 285 IGHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ L D R G + G D K+H +FR IDWD + + PPF P+I NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 344 DV-FDEEKIKDSP 355
D F E ++ +P
Sbjct: 549 DTQFTSEPVQLTP 561
>BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (513), Expect = 6e-54
Identities = 114/313 (36%), Positives = 176/313 (56%), Gaps = 13/313 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGL 114
L DF+ +V+G G++ V LV+ + YAMK+++KE + + I+ EK +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L+ V+ ++ GG++ H+++ K E A+FY A++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+TD+G CK G T T CGTP Y+APEI+ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 232 GMSVDWWSLGVLLFEMSAGHPPF--FASDPMR-----IYEKIVAGKYRCPSHFSVELKDI 284
G SVDWW+LGVL+FEM AG PF +P +++ I+ R P SV+ +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 285 IGHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ L D R G + G D K+H +FR IDWD + + PPF P+I NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 344 DV-FDEEKIKDSP 355
D F E ++ +P
Sbjct: 549 DTQFTSEPVQLTP 561
>AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (513), Expect = 6e-54
Identities = 114/313 (36%), Positives = 176/313 (56%), Gaps = 13/313 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGL 114
L DF+ +V+G G++ V LV+ + YAMK+++KE + + I+ EK +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L+ V+ ++ GG++ H+++ K E A+FY A++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+TD+G CK G T T CGTP Y+APEI+ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 232 GMSVDWWSLGVLLFEMSAGHPPF--FASDPMR-----IYEKIVAGKYRCPSHFSVELKDI 284
G SVDWW+LGVL+FEM AG PF +P +++ I+ R P SV+ +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 285 IGHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ L D R G + G D K+H +FR IDWD + + PPF P+I NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 344 DV-FDEEKIKDSP 355
D F E ++ +P
Sbjct: 549 DTQFTSEPVQLTP 561
>AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (513), Expect = 6e-54
Identities = 114/313 (36%), Positives = 176/313 (56%), Gaps = 13/313 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGL 114
L DF+ +V+G G++ V LV+ + YAMK+++KE + + I+ EK +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L+ V+ ++ GG++ H+++ K E A+FY A++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+TD+G CK G T T CGTP Y+APEI+ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 232 GMSVDWWSLGVLLFEMSAGHPPF--FASDPMR-----IYEKIVAGKYRCPSHFSVELKDI 284
G SVDWW+LGVL+FEM AG PF +P +++ I+ R P SV+ +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 285 IGHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ L D R G + G D K+H +FR IDWD + + PPF P+I NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 344 DV-FDEEKIKDSP 355
D F E ++ +P
Sbjct: 549 DTQFTSEPVQLTP 561
>AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta
protein.
Length = 592
Score = 210 bits (513), Expect = 6e-54
Identities = 114/313 (36%), Positives = 176/313 (56%), Gaps = 13/313 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGL 114
L DF+ +V+G G++ V LV+ + YAMK+++KE + + I+ EK +
Sbjct: 249 LQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L+ V+ ++ GG++ H+++ K E A+FY A++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+TD+G CK G T T CGTP Y+APEI+ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 232 GMSVDWWSLGVLLFEMSAGHPPF--FASDPMR-----IYEKIVAGKYRCPSHFSVELKDI 284
G SVDWW+LGVL+FEM AG PF +P +++ I+ R P SV+ +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 285 IGHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ L D R G + G D K+H +FR IDWD + + PPF P+I NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 344 DV-FDEEKIKDSP 355
D F E ++ +P
Sbjct: 549 DTQFTSEPVQLTP 561
>L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta
protein.
Length = 592
Score = 210 bits (512), Expect = 8e-54
Identities = 114/313 (36%), Positives = 175/313 (55%), Gaps = 13/313 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKIL-CGL 114
L DF+ +V+G G + V LV+ + YAMK+++KE + + I+ EK +
Sbjct: 249 LQDFDLIRVIGRGTYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQAS 308
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
+ PF+V + F+ L+ V+ ++ GG++ H+++ K E A+FY A++ +AL +LH
Sbjct: 309 SNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLH 368
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG---RTWTLCGTPEYLAPEIILSKGY 231
++YRDLK +N+L+D G+IK+TD+G CK G T T CGTP Y+APEI+ + Y
Sbjct: 369 ERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEY 428
Query: 232 GMSVDWWSLGVLLFEMSAGHPPF--FASDPMR-----IYEKIVAGKYRCPSHFSVELKDI 284
G SVDWW+LGVL+FEM AG PF +P +++ I+ R P SV+ +
Sbjct: 429 GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHV 488
Query: 285 IGHVLQVDTTRRYGTL-KDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNF 343
+ L D R G + G D K+H +FR IDWD + + PPF P+I NF
Sbjct: 489 LKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNF 548
Query: 344 DV-FDEEKIKDSP 355
D F E ++ +P
Sbjct: 549 DTQFTSEPVQLTP 561
>AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein.
Length = 1583
Score = 210 bits (512), Expect = 8e-54
Identities = 113/327 (34%), Positives = 178/327 (54%), Gaps = 25/327 (7%)
Query: 39 RQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRL 98
+ D E K++ NDF+ K++ GA+G V+LV+H T + +AMK + K+ ++
Sbjct: 367 QDDLSEGRSSKAKKPPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILR 426
Query: 99 KQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETS 158
QI+ ++ E+ IL PFVV M F+ +L V+ ++ GG+ + L+ +G
Sbjct: 427 NQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEM 486
Query: 159 AKFYGAQVILALEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL--- 214
A+ Y A+ +LALEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 487 ARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEG 546
Query: 215 --------------CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPM 260
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P
Sbjct: 547 HIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPE 606
Query: 261 RIYEKIVAGKYRCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREID 317
++ ++++ P E + +I +LQ + R G G + K H +FR++D
Sbjct: 607 ELFGQVISDDILWPEGDEALPTEAQLLISSLLQTNPLVRLGA--GGAFEVKQHSFFRDLD 664
Query: 318 WDSILNSRIHPPFFPKIRSPGDTTNFD 344
W +L + F P + S DT+ FD
Sbjct: 665 WTGLLRQKAE--FIPHLESEDDTSYFD 689
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 207 bits (506), Expect = 4e-53
Identities = 96/270 (35%), Positives = 168/270 (62%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 54 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 113
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ ALEYLH
Sbjct: 114 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 173
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ YI+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 174 IIHRDLKPENILLNEDMYIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 233
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 234 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 293
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 294 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 323
>AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human
serine-threonine protein kinase R31240_1 protein.
Length = 1237
Score = 207 bits (506), Expect = 4e-53
Identities = 110/309 (35%), Positives = 172/309 (55%), Gaps = 25/309 (8%)
Query: 57 NDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNF 116
NDF+ K++ GA+G V+LV+H T + +AMK + K+ ++ QI+ ++ E+ IL
Sbjct: 13 NDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 72
Query: 117 PFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHAC 176
PFVV M F+ +L V+ ++ GG+ + L+ +G A+ Y A+ +LALEYLH
Sbjct: 73 PFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNY 132
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-----------------CGTP 218
+V+RDLKP+N+LI G+IK+TDFG K+ + T L CGTP
Sbjct: 133 GIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTP 192
Query: 219 EYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCP---S 275
EY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ P
Sbjct: 193 EYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDE 252
Query: 276 HFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIR 335
E + +I +LQ + R G G + K H +FR++DW +L + F P +
Sbjct: 253 ALPTEAQLLISSLLQTNPLVRLGA--GGAFEVKQHSFFRDLDWTGLLRQKAE--FIPHLE 308
Query: 336 SPGDTTNFD 344
S DT+ FD
Sbjct: 309 SEDDTSYFD 317
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 205 bits (501), Expect = 2e-52
Identities = 95/270 (35%), Positives = 168/270 (62%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ ALEYLH
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 200
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ +I+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 260
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 320
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 321 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 350
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 205 bits (501), Expect = 2e-52
Identities = 95/270 (35%), Positives = 168/270 (62%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ ALEYLH
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 200
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ +I+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 260
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 320
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 321 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 350
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 205 bits (501), Expect = 2e-52
Identities = 95/270 (35%), Positives = 168/270 (62%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ ALEYLH
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 200
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ +I+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 260
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 320
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 321 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 350
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 205 bits (501), Expect = 2e-52
Identities = 95/270 (35%), Positives = 168/270 (62%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ ALEYLH
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 200
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ +I+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 260
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 320
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 321 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 350
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 205 bits (501), Expect = 2e-52
Identities = 95/270 (35%), Positives = 168/270 (62%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 73 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 132
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ ALEYLH
Sbjct: 133 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 192
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ +I+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 193 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 252
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 253 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 312
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 313 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 342
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 205 bits (501), Expect = 2e-52
Identities = 95/270 (35%), Positives = 168/270 (62%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 119 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 178
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ ALEYLH
Sbjct: 179 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG 238
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ +I+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 239 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 298
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 299 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 358
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 359 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 388
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 203 bits (495), Expect = 9e-52
Identities = 94/270 (34%), Positives = 167/270 (61%), Gaps = 6/270 (2%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DF+ K+LG G+F V L + + T + YA+K+LEK I++ ++ + E+ ++ L+ P
Sbjct: 81 DFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHP 140
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLHACE 177
F V + + F+D+ LY+ L + GE+ ++RK+G F+ET +FY A+++ A EYLH
Sbjct: 141 FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYLHGKG 200
Query: 178 LVYRDLKPENILIDRTGYIKITDFGFCKLI-----RGRTWTLCGTPEYLAPEIILSKGYG 232
+++RDLKPENIL++ +I+ITDFG K++ + R + GT +Y++PE++ K
Sbjct: 201 IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSAC 260
Query: 233 MSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYRCPSHFSVELKDIIGHVLQVD 292
S D W+LG +++++ AG PPF A + I++KI+ +Y P F + +D++ +L +D
Sbjct: 261 KSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLD 320
Query: 293 TTRRYGTLK-DGVLDFKNHKWFREIDWDSI 321
T+R G + +G K H +F + W+++
Sbjct: 321 ATKRLGCEEMEGYGPLKAHPFFESVTWENL 350
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 202 bits (493), Expect = 2e-51
Identities = 113/308 (36%), Positives = 176/308 (57%), Gaps = 16/308 (5%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
K D+E KV+G GAFG V LV+H T K YAMK+L K ++++ + E+ I+
Sbjct: 72 KAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFA 131
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
N P+VV + Y F+D+ YLY V+ ++ GG++ +L E A+FY A+V+LAL+ +H
Sbjct: 132 NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWARFYTAEVVLALDAIH 190
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLC----GTPEYLAPEIILSKG 230
+ ++RD+KP+N+L+D++G++K+ DFG C + C GTP+Y++PE++ S+G
Sbjct: 191 SMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQG 250
Query: 231 ----YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK----YRCPSHFSVELK 282
YG DWWS+GV L+EM G PF+A + Y KI+ K + + S E K
Sbjct: 251 GDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAK 310
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++I L D R G ++GV + K H +F+ W P P + S DT+N
Sbjct: 311 NLICAFL-TDREVRLG--RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSN 367
Query: 343 FDVFDEEK 350
FD +E+K
Sbjct: 368 FDDLEEDK 375
>DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein
kinase beta (DMPK-like) protein.
Length = 1711
Score = 202 bits (492), Expect = 2e-51
Identities = 111/306 (36%), Positives = 180/306 (58%), Gaps = 20/306 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK T + YAMK+L K ++++ + E+ +L +
Sbjct: 75 DFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQ 134
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D +LY V+ + GG++ + L K K E A+FY +++LA++ +H
Sbjct: 135 WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQL 194
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEII--LSKG 230
V+RD+KP+N+L+D G+I++ DFG C + ++ GTP+Y++PEI+ + G
Sbjct: 195 HYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDG 254
Query: 231 ---YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIV--AGKYRCPSH---FSVELK 282
YG DWWSLGV ++EM G PF+A + Y KI+ +++ PSH S E K
Sbjct: 255 MGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAK 314
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ RR G ++G+ DFK H +F ++W++I N + P+ P + SP DT+N
Sbjct: 315 DLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENIRN--LEAPYIPDVSSPSDTSN 369
Query: 343 FDVFDE 348
FDV D+
Sbjct: 370 FDVDDD 375
>BC048261-1|AAH48261.1| 492|Homo sapiens CDC42BPB protein protein.
Length = 492
Score = 202 bits (492), Expect = 2e-51
Identities = 111/306 (36%), Positives = 180/306 (58%), Gaps = 20/306 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK T + YAMK+L K ++++ + E+ +L +
Sbjct: 75 DFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQ 134
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D +LY V+ + GG++ + L K K E A+FY +++LA++ +H
Sbjct: 135 WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQL 194
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEII--LSKG 230
V+RD+KP+N+L+D G+I++ DFG C + ++ GTP+Y++PEI+ + G
Sbjct: 195 HYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDG 254
Query: 231 ---YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIV--AGKYRCPSH---FSVELK 282
YG DWWSLGV ++EM G PF+A + Y KI+ +++ PSH S E K
Sbjct: 255 MGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAK 314
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ RR G ++G+ DFK H +F ++W++I N + P+ P + SP DT+N
Sbjct: 315 DLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENIRN--LEAPYIPDVSSPSDTSN 369
Query: 343 FDVFDE 348
FDV D+
Sbjct: 370 FDVDDD 375
>BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein.
Length = 933
Score = 202 bits (492), Expect = 2e-51
Identities = 111/306 (36%), Positives = 180/306 (58%), Gaps = 20/306 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK T + YAMK+L K ++++ + E+ +L +
Sbjct: 75 DFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQ 134
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D +LY V+ + GG++ + L K K E A+FY +++LA++ +H
Sbjct: 135 WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQL 194
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEII--LSKG 230
V+RD+KP+N+L+D G+I++ DFG C + ++ GTP+Y++PEI+ + G
Sbjct: 195 HYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDG 254
Query: 231 ---YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIV--AGKYRCPSH---FSVELK 282
YG DWWSLGV ++EM G PF+A + Y KI+ +++ PSH S E K
Sbjct: 255 MGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAK 314
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ RR G ++G+ DFK H +F ++W++I N + P+ P + SP DT+N
Sbjct: 315 DLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENIRN--LEAPYIPDVSSPSDTSN 369
Query: 343 FDVFDE 348
FDV D+
Sbjct: 370 FDVDDD 375
>AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1711
Score = 202 bits (492), Expect = 2e-51
Identities = 111/306 (36%), Positives = 180/306 (58%), Gaps = 20/306 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK T + YAMK+L K ++++ + E+ +L +
Sbjct: 75 DFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQ 134
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D +LY V+ + GG++ + L K K E A+FY +++LA++ +H
Sbjct: 135 WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQL 194
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEII--LSKG 230
V+RD+KP+N+L+D G+I++ DFG C + ++ GTP+Y++PEI+ + G
Sbjct: 195 HYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDG 254
Query: 231 ---YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIV--AGKYRCPSH---FSVELK 282
YG DWWSLGV ++EM G PF+A + Y KI+ +++ PSH S E K
Sbjct: 255 MGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAK 314
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ RR G ++G+ DFK H +F ++W++I N + P+ P + SP DT+N
Sbjct: 315 DLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENIRN--LEAPYIPDVSSPSDTSN 369
Query: 343 FDVFDE 348
FDV D+
Sbjct: 370 FDVDDD 375
>AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.
Length = 1760
Score = 202 bits (492), Expect = 2e-51
Identities = 111/306 (36%), Positives = 180/306 (58%), Gaps = 20/306 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK T + YAMK+L K ++++ + E+ +L +
Sbjct: 124 DFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQ 183
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D +LY V+ + GG++ + L K K E A+FY +++LA++ +H
Sbjct: 184 WITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQL 243
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEII--LSKG 230
V+RD+KP+N+L+D G+I++ DFG C + ++ GTP+Y++PEI+ + G
Sbjct: 244 HYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDG 303
Query: 231 ---YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIV--AGKYRCPSH---FSVELK 282
YG DWWSLGV ++EM G PF+A + Y KI+ +++ PSH S E K
Sbjct: 304 MGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAK 363
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ RR G ++G+ DFK H +F ++W++I N + P+ P + SP DT+N
Sbjct: 364 DLIQRLI-CSRERRLG--QNGIEDFKKHAFFEGLNWENIRN--LEAPYIPDVSSPSDTSN 418
Query: 343 FDVFDE 348
FDV D+
Sbjct: 419 FDVDDD 424
>BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1797
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 503 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 562
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 563 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 622
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 623 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLD 682
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 799
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 800 -FIPQLESEDDTSYFDTRSE 818
>BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 141 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 200
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 201 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 260
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 261 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLD 320
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 321 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 380
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 381 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 437
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 438 -FIPQLESEDDTSYFDTRSE 456
>BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein.
Length = 792
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 141 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 200
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 201 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 260
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 261 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLD 320
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 321 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 380
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 381 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 437
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 438 -FIPQLESEDDTSYFDTRSE 456
>AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 388 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 447
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 448 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 507
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 508 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLD 567
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 568 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 627
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 628 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 684
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 685 -FIPQLESEDDTSYFDTRSE 703
>AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 503 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 562
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 563 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 622
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 623 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLD 682
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 799
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 800 -FIPQLESEDDTSYFDTRSE 818
>AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 388 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 447
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 448 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 507
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 508 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLD 567
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 568 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 627
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 628 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 684
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 685 -FIPQLESEDDTSYFDTRSE 703
>AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 503 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 562
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 563 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 622
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 623 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLD 682
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 799
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 800 -FIPQLESEDDTSYFDTRSE 818
>AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 503 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 562
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 563 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 622
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 623 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLD 682
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 799
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 800 -FIPQLESEDDTSYFDTRSE 818
>AL358075-6|CAI21706.1| 792|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 792
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 388 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 447
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 448 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 507
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 508 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLD 567
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 568 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 627
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 628 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 684
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 685 -FIPQLESEDDTSYFDTRSE 703
>AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 201 bits (491), Expect = 3e-51
Identities = 109/320 (34%), Positives = 171/320 (53%), Gaps = 25/320 (7%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S+ DFE K++ GA+G VFLV+H T + +AMK + K+ ++ QI+ ++ E+
Sbjct: 503 SKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD 562
Query: 110 ILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILA 169
IL PFVV M F +L V+ ++ GG+ + L+ +G + Y A+ +LA
Sbjct: 563 ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLA 622
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKL-IRGRTWTL-------------- 214
LEYLH +V+RDLKP+N+LI G+IK+TDFG K+ + T L
Sbjct: 623 LEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLD 682
Query: 215 ---CGTPEYLAPEIILSKGYGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKY 271
CGTPEY+APE+IL +GYG VDWW++G++L+E G PFF P ++ ++++ +
Sbjct: 683 KQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEI 742
Query: 272 RCP---SHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHP 328
P + +D+ +L + R GT + K H +F +DW +L +
Sbjct: 743 VWPEGDEALPPDAQDLTSKLLHQNPLERLGT--GSAYEVKQHPFFTGLDWTGLLRQKAE- 799
Query: 329 PFFPKIRSPGDTTNFDVFDE 348
F P++ S DT+ FD E
Sbjct: 800 -FIPQLESEDDTSYFDTRSE 818
>U08438-1|AAB60689.1| 689|Homo sapiens beta-adrenergic receptor
kinase protein.
Length = 689
Score = 201 bits (490), Expect = 4e-51
Identities = 116/315 (36%), Positives = 167/315 (53%), Gaps = 14/315 (4%)
Query: 50 SESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKK 109
S S +NDF +++G G FG V+ + TGK YAMK L+K++I ++KQ E ++
Sbjct: 182 STSTLTMNDFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRI-KMKQGETLALNER 240
Query: 110 ILCGL----NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQ 165
I+ L + PF+V M Y F L ++L + GG++ HL + G F E +FY A+
Sbjct: 241 IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE 300
Query: 166 VILALEYLHACELVYRDLKPENILIDRTGYIKITDFGF-CKLIRGRTWTLCGTPEYLAPE 224
+IL LE++H +VYRDLKP NIL+D G+++I+D G C + + GT Y+APE
Sbjct: 301 IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE 360
Query: 225 IILSKG--YGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAGKYRCPSHFSV 279
+L KG Y S DW+SLG +LF++ GH PF D I + P FS
Sbjct: 361 -VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSP 419
Query: 280 ELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGD 339
EL ++ +LQ D RR G L G + K +FR +DW + + PP P
Sbjct: 420 ELHSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNA 479
Query: 340 TTNFDV--FDEEKIK 352
FD+ FDEE K
Sbjct: 480 ADAFDIGSFDEEDTK 494
>M80776-1|AAA58391.1| 689|Homo sapiens receptor kinase protein.
Length = 689
Score = 201 bits (490), Expect = 4e-51
Identities = 114/309 (36%), Positives = 166/309 (53%), Gaps = 14/309 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL- 114
+NDF +++G G FG V+ + TGK YAMK L+K++I ++KQ E ++I+ L
Sbjct: 188 MNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSLV 246
Query: 115 ---NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V M Y F L ++L + GG++ HL + G F E +FY A++IL LE
Sbjct: 247 STGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLE 306
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGF-CKLIRGRTWTLCGTPEYLAPEIILSKG 230
++H +VYRDLKP NIL+D G+++I+D G C + + GT Y+APE +L KG
Sbjct: 307 HMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE-VLQKG 365
Query: 231 --YGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
Y S DW+SLG +LF++ GH PF D I + P FS EL+ ++
Sbjct: 366 VAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLL 425
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+LQ D RR G L G + K +FR +DW + + PP P FD+
Sbjct: 426 EGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDI 485
Query: 346 --FDEEKIK 352
FDEE K
Sbjct: 486 GSFDEEDTK 494
>BC090863-1|AAH90863.1| 689|Homo sapiens ADRBK1 protein protein.
Length = 689
Score = 201 bits (490), Expect = 4e-51
Identities = 114/309 (36%), Positives = 166/309 (53%), Gaps = 14/309 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL- 114
+NDF +++G G FG V+ + TGK YAMK L+K++I ++KQ E ++I+ L
Sbjct: 188 MNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSLV 246
Query: 115 ---NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V M Y F L ++L + GG++ HL + G F E +FY A++IL LE
Sbjct: 247 STGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLE 306
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGF-CKLIRGRTWTLCGTPEYLAPEIILSKG 230
++H +VYRDLKP NIL+D G+++I+D G C + + GT Y+APE +L KG
Sbjct: 307 HMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE-VLQKG 365
Query: 231 --YGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
Y S DW+SLG +LF++ GH PF D I + P FS EL+ ++
Sbjct: 366 VAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLL 425
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+LQ D RR G L G + K +FR +DW + + PP P FD+
Sbjct: 426 EGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDI 485
Query: 346 --FDEEKIK 352
FDEE K
Sbjct: 486 GSFDEEDTK 494
>BC037963-1|AAH37963.1| 689|Homo sapiens adrenergic, beta, receptor
kinase 1 protein.
Length = 689
Score = 201 bits (490), Expect = 4e-51
Identities = 114/309 (36%), Positives = 166/309 (53%), Gaps = 14/309 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL- 114
+NDF +++G G FG V+ + TGK YAMK L+K++I ++KQ E ++I+ L
Sbjct: 188 MNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSLV 246
Query: 115 ---NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V M Y F L ++L + GG++ HL + G F E +FY A++IL LE
Sbjct: 247 STGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLE 306
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGF-CKLIRGRTWTLCGTPEYLAPEIILSKG 230
++H +VYRDLKP NIL+D G+++I+D G C + + GT Y+APE +L KG
Sbjct: 307 HMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE-VLQKG 365
Query: 231 --YGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
Y S DW+SLG +LF++ GH PF D I + P FS EL+ ++
Sbjct: 366 VAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLL 425
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+LQ D RR G L G + K +FR +DW + + PP P FD+
Sbjct: 426 EGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDI 485
Query: 346 --FDEEKIK 352
FDEE K
Sbjct: 486 GSFDEEDTK 494
>X61157-1|CAA43470.1| 689|Homo sapiens beta-adrenergic receptor
kinase protein.
Length = 689
Score = 200 bits (488), Expect = 6e-51
Identities = 115/309 (37%), Positives = 165/309 (53%), Gaps = 14/309 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL- 114
+NDF +++G G FG V+ + TGK YAMK L+K++I ++KQ E ++I+ L
Sbjct: 188 MNDFSVHRIIGRGGFGEVYGCRKRDTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSLV 246
Query: 115 ---NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V M Y F L ++L + GG++ HL + G F E +FY A++IL LE
Sbjct: 247 STGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLE 306
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGF-CKLIRGRTWTLCGTPEYLAPEIILSKG 230
++H +VYRDLKP NIL+D G+++I+D G C + + GT Y+APE +L KG
Sbjct: 307 HMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE-VLQKG 365
Query: 231 --YGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
Y S DW+SLG +LF++ GH PF D I + P FS EL ++
Sbjct: 366 VAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELHSLL 425
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+LQ D RR G L G + K +FR +DW + R PP P FD+
Sbjct: 426 EGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQRYPPPLIPPRGEVNAADAFDI 485
Query: 346 --FDEEKIK 352
FDEE K
Sbjct: 486 GSFDEEDTK 494
>U59305-1|AAB37126.1| 496|Homo sapiens ser-thr protein kinase PK428
protein.
Length = 496
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AL627308-4|CAH71338.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AL451047-2|CAH71184.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AL450063-4|CAI16847.1| 175|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 175
Score = 198 bits (484), Expect = 2e-50
Identities = 84/151 (55%), Positives = 121/151 (80%)
Query: 33 QYLKKLRQDFVESWDDKSESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEK 92
++L K ++DF++ W++ +++NA L DFER+K LGTG+FG V LVKH T +YYAMK+L+K
Sbjct: 25 EFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDK 84
Query: 93 EKIVRLKQIEHSYYEKKILCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG 152
+K+V+LKQIEH+ EK+IL +NFPF+V ++Y FKDN LY V+ ++ GGEMFSHLR++G
Sbjct: 85 QKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIG 144
Query: 153 KFEETSAKFYGAQVILALEYLHACELVYRDL 183
+F E A+FY AQ++L EYLH+ +L+YRDL
Sbjct: 145 RFSEPHARFYAAQIVLTFEYLHSLDLIYRDL 175
>AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AL353689-8|CAI19110.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AJ518976-1|CAD57746.1| 1638|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1638
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 316 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 370
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 371 FDV-DDDCLKNS 381
>AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein
kinase alpha variant protein.
Length = 1702
Score = 198 bits (484), Expect = 2e-50
Identities = 115/312 (36%), Positives = 185/312 (59%), Gaps = 21/312 (6%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 87 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 146
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 147 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 206
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 207 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 266
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSH---FSVELK 282
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ S K
Sbjct: 267 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 326
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
D+I ++ +R + ++G+ DFK H +F IDWD+I N P+ P++ SP DT+N
Sbjct: 327 DLIRRLI---CSREHRLGQNGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSN 381
Query: 343 FDVFDEEKIKDS 354
FDV D++ +K+S
Sbjct: 382 FDV-DDDCLKNS 392
>AY166586-1|AAN86031.1| 1638|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1638
Score = 197 bits (480), Expect = 6e-50
Identities = 111/309 (35%), Positives = 182/309 (58%), Gaps = 15/309 (4%)
Query: 58 DFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGLNFP 117
DFE KV+G GAFG V +VK K +AMK+L K ++++ + E+ +L +
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNK 135
Query: 118 FVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKM-GKFEETSAKFYGAQVILALEYLHAC 176
++ + Y F+D+ LY V+ + GG++ + L K + E A+FY A++++A++ +H
Sbjct: 136 WITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQL 195
Query: 177 ELVYRDLKPENILIDRTGYIKITDFGFC-KLIRGRT---WTLCGTPEYLAPEIILS---- 228
V+RD+KP+NIL+D G+I++ DFG C KL+ T GTP+Y++PEI+ +
Sbjct: 196 HYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDG 255
Query: 229 KG-YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK--YRCPSHFSVELKDII 285
KG YG DWWSLGV ++EM G PF+A + Y KI+ K ++ P+ + ++
Sbjct: 256 KGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAK 315
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+ ++ R + + G+ DFK H +F IDWD+I N P+ P++ SP DT+NFDV
Sbjct: 316 DPIRRLICGREHRLGQSGIEDFKKHPFFSGIDWDNIRN--CEAPYIPEVSSPTDTSNFDV 373
Query: 346 FDEEKIKDS 354
D++ +K+S
Sbjct: 374 -DDDCLKNS 381
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 196 bits (479), Expect = 8e-50
Identities = 111/310 (35%), Positives = 181/310 (58%), Gaps = 20/310 (6%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
K D++ KV+G GAFG V LV+H + K YAMK+L K ++++ + E+ I+
Sbjct: 88 KAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFA 147
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
N P+VV + Y F+D+ YLY V+ ++ GG++ +L E AKFY A+V+LAL+ +H
Sbjct: 148 NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWAKFYTAEVVLALDAIH 206
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLC----GTPEYLAPEIILSKG 230
+ L++RD+KP+N+L+D+ G++K+ DFG C + C GTP+Y++PE++ S+G
Sbjct: 207 SMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG 266
Query: 231 ----YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK----YRCPSHFSVELK 282
YG DWWS+GV L+EM G PF+A + Y KI+ K + + S K
Sbjct: 267 GDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAK 326
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFR--EIDWDSILNSRIHPPFFPKIRSPGDT 340
++I L D R G ++GV + + H +F+ + WD+I + P P++ S D+
Sbjct: 327 NLICAFL-TDREVRLG--RNGVEEIRQHPFFKNDQWHWDNIRETA--APVVPELSSDIDS 381
Query: 341 TNFDVFDEEK 350
+NFD +++K
Sbjct: 382 SNFDDIEDDK 391
>AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein.
Length = 1337
Score = 196 bits (479), Expect = 8e-50
Identities = 111/310 (35%), Positives = 181/310 (58%), Gaps = 20/310 (6%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
K D++ KV+G GAFG V LV+H + K YAMK+L K ++++ + E+ I+
Sbjct: 41 KAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFA 100
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
N P+VV + Y F+D+ YLY V+ ++ GG++ +L E AKFY A+V+LAL+ +H
Sbjct: 101 NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWAKFYTAEVVLALDAIH 159
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLC----GTPEYLAPEIILSKG 230
+ L++RD+KP+N+L+D+ G++K+ DFG C + C GTP+Y++PE++ S+G
Sbjct: 160 SMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG 219
Query: 231 ----YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK----YRCPSHFSVELK 282
YG DWWS+GV L+EM G PF+A + Y KI+ K + + S K
Sbjct: 220 GDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAK 279
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFR--EIDWDSILNSRIHPPFFPKIRSPGDT 340
++I L D R G ++GV + + H +F+ + WD+I + P P++ S D+
Sbjct: 280 NLICAFL-TDREVRLG--RNGVEEIRQHPFFKNDQWHWDNIRETA--APVVPELSSDIDS 334
Query: 341 TNFDVFDEEK 350
+NFD +++K
Sbjct: 335 SNFDDIEDDK 344
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 196 bits (479), Expect = 8e-50
Identities = 111/310 (35%), Positives = 181/310 (58%), Gaps = 20/310 (6%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
K D++ KV+G GAFG V LV+H + K YAMK+L K ++++ + E+ I+
Sbjct: 128 KAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFA 187
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
N P+VV + Y F+D+ YLY V+ ++ GG++ +L E AKFY A+V+LAL+ +H
Sbjct: 188 NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDVPEKWAKFYTAEVVLALDAIH 246
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGFCKLIRGRTWTLC----GTPEYLAPEIILSKG 230
+ L++RD+KP+N+L+D+ G++K+ DFG C + C GTP+Y++PE++ S+G
Sbjct: 247 SMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG 306
Query: 231 ----YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK----YRCPSHFSVELK 282
YG DWWS+GV L+EM G PF+A + Y KI+ K + + S K
Sbjct: 307 GDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAK 366
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFR--EIDWDSILNSRIHPPFFPKIRSPGDT 340
++I L D R G ++GV + + H +F+ + WD+I + P P++ S D+
Sbjct: 367 NLICAFL-TDREVRLG--RNGVEEIRQHPFFKNDQWHWDNIRETA--APVVPELSSDIDS 421
Query: 341 TNFDVFDEEK 350
+NFD +++K
Sbjct: 422 SNFDDIEDDK 431
>AL022329-1|CAB45657.1| 688|Homo sapiens adrenergic, beta, receptor
kinase 2 protein.
Length = 688
Score = 194 bits (474), Expect = 3e-49
Identities = 111/309 (35%), Positives = 165/309 (53%), Gaps = 14/309 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL- 114
+N+F +++G G FG V+ + TGK YAMK L+K++I ++KQ E ++I+ L
Sbjct: 188 MNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSLV 246
Query: 115 ---NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V M Y F L ++L + GG++ HL + G F E +FY ++IL LE
Sbjct: 247 STGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLE 306
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGF-CKLIRGRTWTLCGTPEYLAPEIILSKG 230
++H +VYRDLKP NIL+D G+ +I+D G C + + GT Y+APE +L KG
Sbjct: 307 HMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE-VLQKG 365
Query: 231 --YGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
Y S DW+SLG +LF++ GH PF D I + P FS ELK ++
Sbjct: 366 TAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLL 425
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+LQ D ++R G G + K H +F+ +DW + + PP P FD+
Sbjct: 426 EGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDI 485
Query: 346 --FDEEKIK 352
FDEE K
Sbjct: 486 GSFDEEDTK 494
>X69117-1|CAA48870.1| 688|Homo sapiens beta-adrenergic kinase 2
protein.
Length = 688
Score = 194 bits (473), Expect = 4e-49
Identities = 111/309 (35%), Positives = 165/309 (53%), Gaps = 14/309 (4%)
Query: 56 LNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL- 114
+N+F +++G G FG V+ + TGK YAMK L+K++I ++KQ E ++I+ L
Sbjct: 188 MNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRI-KMKQGETLALNERIMLSLV 246
Query: 115 ---NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALE 171
+ PF+V M Y F L ++L + GG++ HL + G F E +FY ++IL LE
Sbjct: 247 STGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLE 306
Query: 172 YLHACELVYRDLKPENILIDRTGYIKITDFGF-CKLIRGRTWTLCGTPEYLAPEIILSKG 230
++H +VYRDLKP NIL+D G+ +I+D G C + + GT Y+APE +L KG
Sbjct: 307 HVHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE-VLQKG 365
Query: 231 --YGMSVDWWSLGVLLFEMSAGHPPF---FASDPMRIYEKIVAGKYRCPSHFSVELKDII 285
Y S DW+SLG +LF++ GH PF D I + P FS ELK ++
Sbjct: 366 TAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLL 425
Query: 286 GHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTNFDV 345
+LQ D ++R G G + K H +F+ +DW + + PP P FD+
Sbjct: 426 EGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDI 485
Query: 346 --FDEEKIK 352
FDEE K
Sbjct: 486 GSFDEEDTK 494
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 protein.
Length = 1354
Score = 194 bits (473), Expect = 4e-49
Identities = 113/308 (36%), Positives = 177/308 (57%), Gaps = 16/308 (5%)
Query: 55 KLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKILCGL 114
K D+E KV+G GAFG V LV+H T K YAMK+L K ++++ + E+ I+
Sbjct: 72 KAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFA 131
Query: 115 NFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMGKFEETSAKFYGAQVILALEYLH 174
N P+VV + Y F+D+ YLY V+ ++ GG++ +L E A+FY A+V+LAL+ +H
Sbjct: 132 NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLV-NLMSNYDAPEKWARFYTAEVVLALDAIH 190
Query: 175 ACELVYRDLKPENILIDRTGYIKITDFGF-CKLIRG---RTWTLCGTPEYLAPEIILSKG 230
+ ++ D+KP+N+L+D++G++K+ DFG K+ + R T GTP+Y++PE++ S+G
Sbjct: 191 SMGFIHGDVKPDNMLLDKSGHLKLADFGTRMKMNKEGMVRCDTAVGTPDYISPEVLKSQG 250
Query: 231 ----YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGK----YRCPSHFSVELK 282
YG DWWS+GV L+EM G PF+A + Y KI+ K + + S E K
Sbjct: 251 GDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAK 310
Query: 283 DIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPKIRSPGDTTN 342
++I L D R G ++GV + K H +F+ W P P + S DT+N
Sbjct: 311 NLICAFL-TDREVRLG--RNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSN 367
Query: 343 FDVFDEEK 350
FD +E+K
Sbjct: 368 FDDLEEDK 375
>S72883-1|AAB31800.1| 625|Homo sapiens myotonin protein kinase
protein.
Length = 625
Score = 190 bits (463), Expect = 7e-48
Identities = 110/315 (34%), Positives = 171/315 (54%), Gaps = 22/315 (6%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E + +DFE KV+G GAF V +VK TG+ YAMK++ K +++ ++ E+ +
Sbjct: 63 EVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDV 122
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG-KFEETSAKFYGAQVILA 169
L + ++ + + F+D YLY V+ + GG++ + L K G + A+FY A++++A
Sbjct: 123 LVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMA 182
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEI 225
++ +H V+RD+KP+NIL+DR G+I++ DFG C +R R+ GTP+YL+PEI
Sbjct: 183 IDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEI 242
Query: 226 ILSKG-------YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR-----C 273
+ + G YG DWW+LGV +EM G PF+A Y KIV K
Sbjct: 243 LQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLV 302
Query: 274 PSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
E +D I +L T R G + G DF+ H +F +DWD + +S PPF P
Sbjct: 303 DEGVPEEARDFIQRLLCPPET-RLG--RGGAGDFRTHPFFFGLDWDGLRDS--VPPFTPD 357
Query: 334 IRSPGDTTNFDVFDE 348
DT NFD+ ++
Sbjct: 358 FEGATDTCNFDLVED 372
>M94203-1|AAA64884.1| 582|Homo sapiens protein kinase protein.
Length = 582
Score = 190 bits (463), Expect = 7e-48
Identities = 110/315 (34%), Positives = 171/315 (54%), Gaps = 22/315 (6%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E + +DFE KV+G GAF V +VK TG+ YAMK++ K +++ ++ E+ +
Sbjct: 22 EVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDV 81
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG-KFEETSAKFYGAQVILA 169
L + ++ + + F+D YLY V+ + GG++ + L K G + A+FY A++++A
Sbjct: 82 LVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMA 141
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEI 225
++ +H V+RD+KP+NIL+DR G+I++ DFG C +R R+ GTP+YL+PEI
Sbjct: 142 IDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEI 201
Query: 226 ILSKG-------YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR-----C 273
+ + G YG DWW+LGV +EM G PF+A Y KIV K
Sbjct: 202 LQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLV 261
Query: 274 PSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
E +D I +L T R G + G DF+ H +F +DWD + +S PPF P
Sbjct: 262 DEGVPEEARDFIQRLLCPPET-RLG--RGGAGDFRTHPFFFGLDWDGLRDS--VPPFTPD 316
Query: 334 IRSPGDTTNFDVFDE 348
DT NFD+ ++
Sbjct: 317 FEGATDTCNFDLVED 331
>L19268-1|AAA36206.1| 624|Homo sapiens protein kinase protein.
Length = 624
Score = 190 bits (463), Expect = 7e-48
Identities = 110/315 (34%), Positives = 171/315 (54%), Gaps = 22/315 (6%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E + +DFE KV+G GAF V +VK TG+ YAMK++ K +++ ++ E+ +
Sbjct: 63 EVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDV 122
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG-KFEETSAKFYGAQVILA 169
L + ++ + + F+D YLY V+ + GG++ + L K G + A+FY A++++A
Sbjct: 123 LVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMA 182
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEI 225
++ +H V+RD+KP+NIL+DR G+I++ DFG C +R R+ GTP+YL+PEI
Sbjct: 183 IDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEI 242
Query: 226 ILSKG-------YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR-----C 273
+ + G YG DWW+LGV +EM G PF+A Y KIV K
Sbjct: 243 LQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLV 302
Query: 274 PSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
E +D I +L T R G + G DF+ H +F +DWD + +S PPF P
Sbjct: 303 DEGVPEEARDFIQRLLCPPET-RLG--RGGAGDFRTHPFFFGLDWDGLRDS--VPPFTPD 357
Query: 334 IRSPGDTTNFDVFDE 348
DT NFD+ ++
Sbjct: 358 FEGATDTCNFDLVED 372
>L08835-5|AAC14450.1| 530|Homo sapiens myotonic dystrophy kinase
protein.
Length = 530
Score = 190 bits (463), Expect = 7e-48
Identities = 110/315 (34%), Positives = 171/315 (54%), Gaps = 22/315 (6%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E + +DFE KV+G GAF V +VK TG+ YAMK++ K +++ ++ E+ +
Sbjct: 63 EVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDV 122
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG-KFEETSAKFYGAQVILA 169
L + ++ + + F+D YLY V+ + GG++ + L K G + A+FY A++++A
Sbjct: 123 LVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMA 182
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEI 225
++ +H V+RD+KP+NIL+DR G+I++ DFG C +R R+ GTP+YL+PEI
Sbjct: 183 IDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEI 242
Query: 226 ILSKG-------YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR-----C 273
+ + G YG DWW+LGV +EM G PF+A Y KIV K
Sbjct: 243 LQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLV 302
Query: 274 PSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
E +D I +L T R G + G DF+ H +F +DWD + +S PPF P
Sbjct: 303 DEGVPEEARDFIQRLLCPPET-RLG--RGGAGDFRTHPFFFGLDWDGLRDS--VPPFTPD 357
Query: 334 IRSPGDTTNFDVFDE 348
DT NFD+ ++
Sbjct: 358 FEGATDTCNFDLVED 372
>L08835-4|AAC14451.1| 535|Homo sapiens myotonic dystrophy kinase
protein.
Length = 535
Score = 190 bits (463), Expect = 7e-48
Identities = 110/315 (34%), Positives = 171/315 (54%), Gaps = 22/315 (6%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E + +DFE KV+G GAF V +VK TG+ YAMK++ K +++ ++ E+ +
Sbjct: 63 EVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDV 122
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG-KFEETSAKFYGAQVILA 169
L + ++ + + F+D YLY V+ + GG++ + L K G + A+FY A++++A
Sbjct: 123 LVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMA 182
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEI 225
++ +H V+RD+KP+NIL+DR G+I++ DFG C +R R+ GTP+YL+PEI
Sbjct: 183 IDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEI 242
Query: 226 ILSKG-------YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR-----C 273
+ + G YG DWW+LGV +EM G PF+A Y KIV K
Sbjct: 243 LQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLV 302
Query: 274 PSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
E +D I +L T R G + G DF+ H +F +DWD + +S PPF P
Sbjct: 303 DEGVPEEARDFIQRLLCPPET-RLG--RGGAGDFRTHPFFFGLDWDGLRDS--VPPFTPD 357
Query: 334 IRSPGDTTNFDVFDE 348
DT NFD+ ++
Sbjct: 358 FEGATDTCNFDLVED 372
>L08835-3|AAC14448.1| 624|Homo sapiens myotonic dystrophy kinase
protein.
Length = 624
Score = 190 bits (463), Expect = 7e-48
Identities = 110/315 (34%), Positives = 171/315 (54%), Gaps = 22/315 (6%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E + +DFE KV+G GAF V +VK TG+ YAMK++ K +++ ++ E+ +
Sbjct: 63 EVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDV 122
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG-KFEETSAKFYGAQVILA 169
L + ++ + + F+D YLY V+ + GG++ + L K G + A+FY A++++A
Sbjct: 123 LVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMA 182
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEI 225
++ +H V+RD+KP+NIL+DR G+I++ DFG C +R R+ GTP+YL+PEI
Sbjct: 183 IDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEI 242
Query: 226 ILSKG-------YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR-----C 273
+ + G YG DWW+LGV +EM G PF+A Y KIV K
Sbjct: 243 LQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLV 302
Query: 274 PSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
E +D I +L T R G + G DF+ H +F +DWD + +S PPF P
Sbjct: 303 DEGVPEEARDFIQRLLCPPET-RLG--RGGAGDFRTHPFFFGLDWDGLRDS--VPPFTPD 357
Query: 334 IRSPGDTTNFDVFDE 348
DT NFD+ ++
Sbjct: 358 FEGATDTCNFDLVED 372
>L08835-2|AAC14449.1| 629|Homo sapiens myotonic dystrophy kinase
protein.
Length = 629
Score = 190 bits (463), Expect = 7e-48
Identities = 110/315 (34%), Positives = 171/315 (54%), Gaps = 22/315 (6%)
Query: 51 ESNAKLNDFERQKVLGTGAFGIVFLVKHIVTGKYYAMKMLEKEKIVRLKQIEHSYYEKKI 110
E + +DFE KV+G GAF V +VK TG+ YAMK++ K +++ ++ E+ +
Sbjct: 63 EVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDV 122
Query: 111 LCGLNFPFVVYMKYYFKDNVYLYYVLPFIAGGEMFSHLRKMG-KFEETSAKFYGAQVILA 169
L + ++ + + F+D YLY V+ + GG++ + L K G + A+FY A++++A
Sbjct: 123 LVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMA 182
Query: 170 LEYLHACELVYRDLKPENILIDRTGYIKITDFGFCKLIRG----RTWTLCGTPEYLAPEI 225
++ +H V+RD+KP+NIL+DR G+I++ DFG C +R R+ GTP+YL+PEI
Sbjct: 183 IDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEI 242
Query: 226 ILSKG-------YGMSVDWWSLGVLLFEMSAGHPPFFASDPMRIYEKIVAGKYR-----C 273
+ + G YG DWW+LGV +EM G PF+A Y KIV K
Sbjct: 243 LQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLV 302
Query: 274 PSHFSVELKDIIGHVLQVDTTRRYGTLKDGVLDFKNHKWFREIDWDSILNSRIHPPFFPK 333
E +D I +L T R G + G DF+ H +F +DWD + +S PPF P
Sbjct: 303 DEGVPEEARDFIQRLLCPPET-RLG--RGGAGDFRTHPFFFGLDWDGLRDS--VPPFTPD 357
Query: 334 IRSPGDTTNFDVFDE 348
DT NFD+ ++
Sbjct: 358 FEGATDTCNFDLVED 372
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.142 0.442
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 59,014,998
Number of Sequences: 224733
Number of extensions: 2629173
Number of successful extensions: 11673
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2509
Number of HSP's successfully gapped in prelim test: 279
Number of HSP's that attempted gapping in prelim test: 4512
Number of HSP's gapped (non-prelim): 3312
length of query: 366
length of database: 73,234,838
effective HSP length: 91
effective length of query: 275
effective length of database: 52,784,135
effective search space: 14515637125
effective search space used: 14515637125
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 66 (30.7 bits)
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