BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001162-TA|BGIBMGA001162-PA|IPR002401|E-class P450, group I, IPR001128|Cytochrome P450 (556 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9VYY4 Cluster: Cytochrome P450 4g15; n=8; Neoptera|Rep... 745 0.0 UniRef50_Q9V3S0 Cluster: Cytochrome P450 4g1; n=62; Protostomia|... 508 e-142 UniRef50_Q967Y5 Cluster: Cytochrome P450 CYP4G13v2; n=4; Neopter... 480 e-134 UniRef50_Q16ML8 Cluster: Cytochrome P450; n=3; Culicidae|Rep: Cy... 381 e-104 UniRef50_A0A8M5 Cluster: Cytochrome P450 4 family; n=1; Daphnia ... 369 e-100 UniRef50_O76478 Cluster: Corpora allata cytochrome P450; n=2; Ne... 347 3e-94 UniRef50_UPI00015B560A Cluster: PREDICTED: similar to cytochrome... 335 2e-90 UniRef50_A7SWY9 Cluster: Predicted protein; n=3; Nematostella ve... 327 5e-88 UniRef50_A0MNW4 Cluster: Cyp4M9; n=20; Obtectomera|Rep: Cyp4M9 -... 313 7e-84 UniRef50_Q964T1 Cluster: Cytochrome P450 4c21; n=1; Blattella ge... 309 1e-82 UniRef50_Q6VAB7 Cluster: Cytochrome P450 CYP4AB2; n=6; Apocrita|... 308 3e-82 UniRef50_Q27589 Cluster: Cytochrome P450 4d2; n=8; Acalyptratae|... 306 8e-82 UniRef50_UPI00015B5D09 Cluster: PREDICTED: similar to cytochrome... 300 5e-80 UniRef50_Q9Y1T8 Cluster: Cytochrome P450 4W1; n=3; Arthropoda|Re... 299 1e-79 UniRef50_UPI00015B569D Cluster: PREDICTED: similar to cytochrome... 277 4e-73 UniRef50_Q9NB96 Cluster: P450 CYP319A1; n=2; Parasitiformes|Rep:... 275 2e-72 UniRef50_UPI00015B604A Cluster: PREDICTED: similar to cytochrome... 271 3e-71 UniRef50_Q9VA27 Cluster: Cytochrome P450 4c3; n=15; Coelomata|Re... 262 1e-68 UniRef50_O45120 Cluster: Family 4 cytochrome P450; n=2; Coptoter... 253 1e-65 UniRef50_Q9VVN6 Cluster: Probable cytochrome P450 312a1; n=2; So... 242 2e-62 UniRef50_UPI00015B5014 Cluster: PREDICTED: similar to cytochrome... 239 1e-61 UniRef50_UPI0000D566B3 Cluster: PREDICTED: similar to Cytochrome... 237 6e-61 UniRef50_Q6ZWL3 Cluster: Cytochrome P450 4V2; n=83; Coelomata|Re... 226 1e-57 UniRef50_UPI0000E46807 Cluster: PREDICTED: similar to cytochrome... 226 1e-57 UniRef50_UPI00015B561A Cluster: PREDICTED: similar to cytochrome... 225 2e-57 UniRef50_A0JMQ6 Cluster: Cytochrome P450, family 4, subfamily V,... 221 3e-56 UniRef50_Q9NGQ5 Cluster: Insecticide resistance-associated cytoc... 219 2e-55 UniRef50_A1BPS2 Cluster: CYP4BF1; n=2; Ips paraconfusus|Rep: CYP... 213 1e-53 UniRef50_Q178T9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 210 7e-53 UniRef50_Q695H3 Cluster: Pheromone-degrading enzyme; n=2; Phyllo... 210 1e-52 UniRef50_UPI0000D55ACE Cluster: PREDICTED: similar to Cytochrome... 209 2e-52 UniRef50_Q170T4 Cluster: Cytochrome P450; n=5; Endopterygota|Rep... 209 2e-52 UniRef50_Q8ISJ8 Cluster: Cytochrome P450 CYP4S4; n=3; Noctuidae|... 208 2e-52 UniRef50_O17851 Cluster: Putative uncharacterized protein cyp-37... 208 3e-52 UniRef50_UPI0000D55B03 Cluster: PREDICTED: similar to Cytochrome... 206 1e-51 UniRef50_UPI0000D55952 Cluster: PREDICTED: similar to Cytochrome... 205 3e-51 UniRef50_Q27472 Cluster: Cytochrome p450 family protein 32A1; n=... 204 6e-51 UniRef50_Q9U1R5 Cluster: Putative uncharacterized protein cyp-42... 203 8e-51 UniRef50_UPI0000D56462 Cluster: PREDICTED: similar to cytochrome... 202 2e-50 UniRef50_UPI0000D56049 Cluster: PREDICTED: similar to Probable c... 201 4e-50 UniRef50_Q7YXL0 Cluster: Cytochrome P450 monooxygenase; n=2; Tri... 200 6e-50 UniRef50_UPI00015B569E Cluster: PREDICTED: similar to cytochrome... 198 3e-49 UniRef50_Q179B7 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 198 3e-49 UniRef50_Q16IS6 Cluster: Cytochrome P450; n=12; Culicidae|Rep: C... 196 2e-48 UniRef50_UPI0000E46144 Cluster: PREDICTED: similar to ENSANGP000... 195 3e-48 UniRef50_Q9N574 Cluster: Cytochrome p450 family protein 31A3; n=... 195 3e-48 UniRef50_Q9N4Q5 Cluster: Cytochrome p450 family protein 32B1; n=... 194 5e-48 UniRef50_Q7YSZ3 Cluster: P450 enzyme precursor; n=1; Rhodnius pr... 192 3e-47 UniRef50_UPI0000D5646A Cluster: PREDICTED: similar to CYtochrome... 191 4e-47 UniRef50_Q9VS79 Cluster: Cytochrome P450 4d8; n=6; Schizophora|R... 190 6e-47 UniRef50_Q170T0 Cluster: Cytochrome P450; n=12; Culicidae|Rep: C... 190 1e-46 UniRef50_Q9V7G5 Cluster: Probable cytochrome P450 4aa1; n=5; Dip... 190 1e-46 UniRef50_Q8ISJ7 Cluster: Cytochrome P450 CYP4L4; n=4; Noctuidae|... 189 2e-46 UniRef50_A1BPS3 Cluster: CYP4BG1; n=1; Ips paraconfusus|Rep: CYP... 188 3e-46 UniRef50_Q16I47 Cluster: Cytochrome P450; n=7; Culicidae|Rep: Cy... 188 4e-46 UniRef50_Q9VMS9 Cluster: Probable cytochrome P450 4ac1; n=5; Sop... 187 8e-46 UniRef50_P33269 Cluster: Cytochrome P450 4d1; n=11; Diptera|Rep:... 186 1e-45 UniRef50_Q9XVA6 Cluster: Putative uncharacterized protein cyp-37... 186 1e-45 UniRef50_Q4R1I7 Cluster: Cytochrome P450; n=1; Papilio xuthus|Re... 186 1e-45 UniRef50_A1BPR9 Cluster: CYP4BD1; n=1; Ips paraconfusus|Rep: CYP... 186 2e-45 UniRef50_Q9VXY0 Cluster: Probable cytochrome P450 4s3; n=5; Acal... 186 2e-45 UniRef50_UPI0000D9991B Cluster: PREDICTED: similar to cytochrome... 184 5e-45 UniRef50_A1BPS5 Cluster: CYP4BJ1; n=1; Ips paraconfusus|Rep: CYP... 184 5e-45 UniRef50_A6Y7S1 Cluster: Female neotenic-specific protein 4; n=1... 184 7e-45 UniRef50_A1BPS4 Cluster: CYP4BH1; n=1; Ips paraconfusus|Rep: CYP... 183 1e-44 UniRef50_Q16TD6 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 183 1e-44 UniRef50_P13584 Cluster: Cytochrome P450 4B1; n=32; Euteleostomi... 182 2e-44 UniRef50_UPI00015B61D7 Cluster: PREDICTED: similar to Cytochrome... 180 7e-44 UniRef50_Q02928 Cluster: Cytochrome P450 4A11 precursor; n=114; ... 180 1e-43 UniRef50_UPI00015B5E04 Cluster: PREDICTED: similar to CG8302-PA;... 178 4e-43 UniRef50_Q9N525 Cluster: Cytochrome p450 family protein 29A3; n=... 177 5e-43 UniRef50_UPI00015B4DC8 Cluster: PREDICTED: similar to corpora al... 177 6e-43 UniRef50_UPI0000D56470 Cluster: PREDICTED: similar to Cytochrome... 177 6e-43 UniRef50_UPI0000F2BA18 Cluster: PREDICTED: similar to Cytochrome... 177 8e-43 UniRef50_UPI00015B5196 Cluster: PREDICTED: similar to cytochrome... 176 1e-42 UniRef50_Q4U3Y4 Cluster: CYP325C2; n=4; Anopheles gambiae|Rep: C... 175 3e-42 UniRef50_Q6PW73 Cluster: Cytochrome P450 CYP4AT1; n=1; Capitella... 175 3e-42 UniRef50_Q8K4D6 Cluster: Cytochrome P450 4X1; n=15; Eutheria|Rep... 172 2e-41 UniRef50_Q17DZ0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 171 3e-41 UniRef50_Q27606 Cluster: Cytochrome P450 4e2; n=11; Diptera|Rep:... 170 1e-40 UniRef50_Q16L55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 169 1e-40 UniRef50_Q170T3 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 169 2e-40 UniRef50_Q6NT55 Cluster: Cytochrome P450 4F22; n=127; Deuterosto... 168 4e-40 UniRef50_Q9V558 Cluster: Cytochrome P450 4p1; n=5; Sophophora|Re... 167 5e-40 UniRef50_Q6TGT4 Cluster: Thromboxane A synthase 1; n=6; cellular... 167 9e-40 UniRef50_Q16P39 Cluster: Cytochrome P450; n=7; Aedes aegypti|Rep... 166 1e-39 UniRef50_Q8N118 Cluster: Cytochrome P450 4X1; n=12; Mammalia|Rep... 166 2e-39 UniRef50_A1BPR7 Cluster: CYP4AY1; n=2; Ips paraconfusus|Rep: CYP... 165 2e-39 UniRef50_Q170S9 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cy... 165 4e-39 UniRef50_UPI00015B5723 Cluster: PREDICTED: similar to cytochrome... 164 6e-39 UniRef50_Q17PE3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep... 164 6e-39 UniRef50_O46054 Cluster: Cytochrome P450 4ae1; n=1; Drosophila m... 164 6e-39 UniRef50_Q9VLZ7 Cluster: Probable cytochrome P450 4d21; n=5; Sop... 163 8e-39 UniRef50_Q4STK8 Cluster: Chromosome undetermined SCAF14158, whol... 163 1e-38 UniRef50_Q177R7 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep... 162 3e-38 UniRef50_UPI0001555B83 Cluster: PREDICTED: similar to cytochrome... 161 3e-38 UniRef50_Q16L50 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 161 4e-38 UniRef50_Q6SPQ6 Cluster: CYP4BB1; n=2; Protostomia|Rep: CYP4BB1 ... 161 6e-38 UniRef50_Q17PE0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 160 1e-37 UniRef50_Q7QCC3 Cluster: ENSANGP00000012179; n=1; Anopheles gamb... 156 1e-36 UniRef50_UPI0000D56467 Cluster: PREDICTED: similar to Cytochrome... 156 2e-36 UniRef50_Q16E69 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 156 2e-36 UniRef50_UPI0000D56469 Cluster: PREDICTED: similar to cytochrome... 155 2e-36 UniRef50_Q176V3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep... 155 2e-36 UniRef50_Q178V0 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cy... 155 4e-36 UniRef50_UPI0000D5558E Cluster: PREDICTED: similar to Cytochrome... 151 4e-35 UniRef50_Q9VGB4 Cluster: Probable cytochrome P450 313a2; n=2; Dr... 150 8e-35 UniRef50_Q5XM61 Cluster: Cytochrome P450; n=9; Pancrustacea|Rep:... 149 1e-34 UniRef50_Q6PH32 Cluster: Cytochrome P450, family 4; n=7; Clupeoc... 149 2e-34 UniRef50_Q8WQN5 Cluster: Cytochrome P450 CYP4H14; n=22; Endopter... 149 2e-34 UniRef50_Q095M8 Cluster: Cytochrome P450 4A5; n=1; Stigmatella a... 148 4e-34 UniRef50_Q5V5P9 Cluster: Cytochrome P450; n=3; Halobacteriaceae|... 148 4e-34 UniRef50_A6GGL1 Cluster: Cytochrome P450 family protein; n=1; Pl... 147 8e-34 UniRef50_Q9VG40 Cluster: Probable cytochrome P450 313a4; n=3; So... 147 8e-34 UniRef50_UPI00005A2E9B Cluster: PREDICTED: similar to cytochrome... 146 1e-33 UniRef50_UPI0000F21E21 Cluster: PREDICTED: similar to cytochrome... 146 2e-33 UniRef50_UPI0000D55FA3 Cluster: PREDICTED: similar to Cytochrome... 145 3e-33 UniRef50_A7RNE6 Cluster: Predicted protein; n=1; Nematostella ve... 145 3e-33 UniRef50_A7SJV6 Cluster: Predicted protein; n=3; Nematostella ve... 144 4e-33 UniRef50_UPI0000D56428 Cluster: PREDICTED: similar to Cytochrome... 144 5e-33 UniRef50_Q6SPQ5 Cluster: CYP342A1; n=1; Nereis virens|Rep: CYP34... 144 5e-33 UniRef50_UPI0000E4657A Cluster: PREDICTED: similar to cytochrome... 144 7e-33 UniRef50_Q06GC7 Cluster: Cytochrome P450; n=1; Rhodococcus sp. N... 142 2e-32 UniRef50_Q16L53 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 142 3e-32 UniRef50_Q179B9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 141 4e-32 UniRef50_A7SXR0 Cluster: Predicted protein; n=5; Nematostella ve... 141 4e-32 UniRef50_Q8UF31 Cluster: Cytochrome P450; n=1; Agrobacterium tum... 140 7e-32 UniRef50_Q8T632 Cluster: Cytochrome P450 CYP6P3; n=42; Diptera|R... 140 7e-32 UniRef50_Q86GR1 Cluster: Cytochrome P450 CYPm3r5; n=12; Culicida... 140 7e-32 UniRef50_Q89R90 Cluster: Blr2882 protein; n=4; Bacteria|Rep: Blr... 140 9e-32 UniRef50_A7D7T8 Cluster: Cytochrome P450; n=1; Halorubrum lacusp... 140 1e-31 UniRef50_UPI00015B4AC4 Cluster: PREDICTED: similar to cytochrome... 139 2e-31 UniRef50_Q82D73 Cluster: Putative cytochrome P450; n=2; Streptom... 139 2e-31 UniRef50_Q4U3Y5 Cluster: CYP325D1; n=1; Anopheles gambiae|Rep: C... 139 2e-31 UniRef50_Q5U3Q3 Cluster: Cytochrome P450, family 3, subfamily c,... 139 2e-31 UniRef50_Q9BID0 Cluster: Cytochrome P450; n=27; Culicidae|Rep: C... 139 2e-31 UniRef50_Q7QH22 Cluster: ENSANGP00000012679; n=5; Cellia|Rep: EN... 138 3e-31 UniRef50_P05184 Cluster: Cytochrome P450 3A3; n=159; Euteleostom... 138 3e-31 UniRef50_Q8WQN1 Cluster: Cytochrome P450 CYP4H24; n=23; Culicida... 138 4e-31 UniRef50_Q0IG08 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 138 4e-31 UniRef50_O76107 Cluster: Cytochrome P450; n=2; Culicini|Rep: Cyt... 138 4e-31 UniRef50_UPI00015B5073 Cluster: PREDICTED: similar to cytochrome... 137 6e-31 UniRef50_UPI0000D56468 Cluster: PREDICTED: similar to Cytochrome... 137 6e-31 UniRef50_UPI0000D555E9 Cluster: PREDICTED: similar to Cytochrome... 137 6e-31 UniRef50_A5P357 Cluster: Cytochrome P450; n=1; Methylobacterium ... 137 6e-31 UniRef50_Q3E385 Cluster: Cytochrome P450; n=3; Chloroflexus|Rep:... 137 8e-31 UniRef50_Q9V4T3 Cluster: Probable cytochrome P450 4ad1; n=2; Sop... 137 8e-31 UniRef50_Q3I414 Cluster: Cytochrome P450; n=18; Cucujiformia|Rep... 136 1e-30 UniRef50_UPI0000D576F7 Cluster: PREDICTED: similar to Cytochrome... 136 2e-30 UniRef50_Q0LLJ2 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 136 2e-30 UniRef50_UPI00015B5352 Cluster: PREDICTED: similar to cytochrome... 135 3e-30 UniRef50_Q98T91 Cluster: Cytochrome P450 3A40; n=16; Euteleostom... 135 3e-30 UniRef50_Q9PWP0 Cluster: Cytochrome P450; n=2; Dicentrarchus lab... 135 3e-30 UniRef50_Q8WQN9 Cluster: Cytochrome P450 CYP4J5; n=22; Endoptery... 134 4e-30 UniRef50_UPI0000E4963D Cluster: PREDICTED: similar to cytochrome... 134 6e-30 UniRef50_UPI0000E48EAF Cluster: PREDICTED: similar to cytochrome... 134 6e-30 UniRef50_UPI000065CBAF Cluster: Thromboxane-A synthase (EC 5.3.9... 134 8e-30 UniRef50_Q1D9Z9 Cluster: Cytochrome P450 family protein; n=1; My... 134 8e-30 UniRef50_Q5TXA2 Cluster: ENSANGP00000026709; n=2; Anopheles gamb... 134 8e-30 UniRef50_Q495Y1 Cluster: CYP3A43 protein; n=4; Homo sapiens|Rep:... 134 8e-30 UniRef50_Q0IEL1 Cluster: Cytochrome P450; n=6; Culicini|Rep: Cyt... 133 1e-29 UniRef50_A7DM29 Cluster: Cytochrome P450; n=2; Methylobacterium ... 133 1e-29 UniRef50_Q9PVE8 Cluster: Cytochrome P450 3A30; n=4; Percomorpha|... 133 1e-29 UniRef50_O76345 Cluster: Cytochrome P450; n=1; Homarus americanu... 132 2e-29 UniRef50_Q70AR5 Cluster: Putative cytochrome P450; n=1; Streptom... 132 2e-29 UniRef50_Q9VGB5 Cluster: Probable cytochrome P450 313a5; n=2; Dr... 132 2e-29 UniRef50_Q309A5 Cluster: Cytochrome P450 monooxygenase; n=22; Ap... 132 3e-29 UniRef50_P33270 Cluster: Cytochrome P450 6a2; n=10; Diptera|Rep:... 132 3e-29 UniRef50_Q9VYQ7 Cluster: Probable cytochrome P450 311a1; n=2; Dr... 132 3e-29 UniRef50_UPI00015B480C Cluster: PREDICTED: similar to cytochrome... 131 4e-29 UniRef50_A7RQ80 Cluster: Predicted protein; n=5; Nematostella ve... 131 4e-29 UniRef50_O16156 Cluster: Cytochrome P450 30; n=1; Mercenaria mer... 131 5e-29 UniRef50_A1UDQ6 Cluster: Cytochrome P450; n=10; Mycobacterium|Re... 130 1e-28 UniRef50_A7RSL1 Cluster: Predicted protein; n=2; Nematostella ve... 130 1e-28 UniRef50_A3RK60 Cluster: Cytochrome P450; n=2; Liposcelis bostry... 130 1e-28 UniRef50_UPI0000D56564 Cluster: PREDICTED: similar to Probable c... 129 2e-28 UniRef50_Q29AT3 Cluster: GA11819-PA; n=6; Diptera|Rep: GA11819-P... 129 2e-28 UniRef50_Q964R1 Cluster: Cytochrome P450 6j1; n=1; Blattella ger... 129 2e-28 UniRef50_UPI00015B60B4 Cluster: PREDICTED: similar to cytochrome... 128 3e-28 UniRef50_Q0LK65 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 128 3e-28 UniRef50_Q9KFA6 Cluster: Cytochrome P450 hydroxylase; n=1; Bacil... 128 4e-28 UniRef50_Q9VGB3 Cluster: Probable cytochrome P450 313a3; n=2; Dr... 128 4e-28 UniRef50_UPI00015B595F Cluster: PREDICTED: similar to cytochrome... 128 5e-28 UniRef50_Q629N7 Cluster: Cytochrome P450-related protein; n=24; ... 128 5e-28 UniRef50_Q5W1K8 Cluster: Cytochrome P450 CYP6AX1 protein; n=2; H... 127 7e-28 UniRef50_UPI0000D56E82 Cluster: PREDICTED: similar to Cytochrome... 127 9e-28 UniRef50_A0NQ01 Cluster: Cytochrome P450; n=1; Stappia aggregata... 127 9e-28 UniRef50_Q6PW74 Cluster: Cytochrome P450 CYP331A1; n=1; Capitell... 127 9e-28 UniRef50_Q8WQM9 Cluster: Cytochrome P450 CYP6M1; n=7; Culicidae|... 126 1e-27 UniRef50_Q162V4 Cluster: Cytochrome P450 family protein, putativ... 126 2e-27 UniRef50_Q3IR83 Cluster: Unspecific monooxygenase; n=1; Natronom... 126 2e-27 UniRef50_UPI0000DB7C31 Cluster: PREDICTED: similar to Probable c... 126 2e-27 UniRef50_Q70AR1 Cluster: Putative cytochrome P450; n=1; Streptom... 126 2e-27 UniRef50_Q3L917 Cluster: Cytochrome P450; n=1; Rhodococcus eryth... 126 2e-27 UniRef50_Q5KR92 Cluster: Cytochrome P450; n=1; Hodotermopsis sjo... 125 3e-27 UniRef50_A7SCY4 Cluster: Predicted protein; n=1; Nematostella ve... 125 3e-27 UniRef50_Q27594 Cluster: Cytochrome P450 6a9; n=15; Schizophora|... 125 3e-27 UniRef50_A3RIC1 Cluster: Cytochrome P450; n=1; Bombyx mori|Rep: ... 125 4e-27 UniRef50_Q8MZK0 Cluster: Cytochrome P450; n=6; Culicidae|Rep: Cy... 124 5e-27 UniRef50_UPI0000D576F6 Cluster: PREDICTED: similar to Probable c... 124 8e-27 UniRef50_Q9V4U7 Cluster: Probable cytochrome P450 6a14; n=10; Sc... 124 8e-27 UniRef50_Q1IM54 Cluster: Cytochrome P450; n=1; Acidobacteria bac... 123 1e-26 UniRef50_A7LFI0 Cluster: Cytochrome P450; n=3; Tribolium castane... 123 1e-26 UniRef50_Q0LL77 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 123 1e-26 UniRef50_A7SRX7 Cluster: Predicted protein; n=2; Nematostella ve... 123 1e-26 UniRef50_Q964T2 Cluster: Cytochrome P450 9e2; n=2; Blattaria|Rep... 122 2e-26 UniRef50_Q9V769 Cluster: Cytochrome P450 6a22; n=2; Sophophora|R... 122 2e-26 UniRef50_Q825N1 Cluster: Cytochrome P450 hydroxylase; n=6; Actin... 122 3e-26 UniRef50_Q0LFI0 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 122 3e-26 UniRef50_A7T1A2 Cluster: Predicted protein; n=2; Nematostella ve... 122 3e-26 UniRef50_Q9GQM9 Cluster: Cytochrome P450 6l1; n=1; Blattella ger... 122 3e-26 UniRef50_UPI0000D5650B Cluster: PREDICTED: similar to Cytochrome... 122 3e-26 UniRef50_UPI00015B4FBC Cluster: PREDICTED: similar to cytochrome... 121 4e-26 UniRef50_Q0LJ67 Cluster: Cytochrome P450; n=2; cellular organism... 121 4e-26 UniRef50_Q27691 Cluster: Cytochrome P450; n=2; Musca domestica|R... 121 4e-26 UniRef50_P29980 Cluster: Probable cytochrome P450 110; n=2; Nost... 121 4e-26 UniRef50_Q16F55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 121 6e-26 UniRef50_Q069I9 Cluster: Gossypol-induced cytochrome P450; n=9; ... 120 8e-26 UniRef50_UPI0000DB6FEA Cluster: PREDICTED: similar to Probable c... 120 1e-25 UniRef50_UPI0000D577ED Cluster: PREDICTED: similar to Cytochrome... 119 2e-25 UniRef50_A7HP72 Cluster: Cytochrome P450; n=1; Parvibaculum lava... 119 2e-25 UniRef50_A5HG33 Cluster: Cytochrome P450 monooxygenase CYP6AE; n... 119 2e-25 UniRef50_UPI00015B60BE Cluster: PREDICTED: similar to cytochrome... 119 2e-25 UniRef50_Q0GBX4 Cluster: Cytochrome P450 CYP3-like member 1; n=1... 119 2e-25 UniRef50_Q27664 Cluster: Cytochrome P450 6B2; n=46; Obtectomera|... 119 2e-25 UniRef50_UPI0000E48111 Cluster: PREDICTED: similar to cytochrome... 118 3e-25 UniRef50_UPI0000E480BF Cluster: PREDICTED: similar to cytochrome... 118 3e-25 UniRef50_UPI0000E473D8 Cluster: PREDICTED: hypothetical protein;... 118 3e-25 UniRef50_A7DLL5 Cluster: Cytochrome P450; n=1; Methylobacterium ... 118 3e-25 UniRef50_Q695H1 Cluster: Antennae-rich cytochrome P450; n=3; Pol... 118 3e-25 UniRef50_A4FHE9 Cluster: Bifunctional P-450:NADPH-P450 reductase... 118 4e-25 UniRef50_Q964R0 Cluster: Cytochrome P450 6k1; n=1; Blattella ger... 118 4e-25 UniRef50_UPI0000D561ED Cluster: PREDICTED: similar to Probable c... 118 5e-25 UniRef50_UPI00015A5D7D Cluster: hypothetical protein LOC10003739... 118 5e-25 UniRef50_Q3EBT7 Cluster: Uncharacterized protein At2g26170.1; n=... 118 5e-25 UniRef50_Q8T624 Cluster: Cytochrome P450 CYP9L1 protein; n=6; Ce... 118 5e-25 UniRef50_Q16FQ1 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep... 118 5e-25 UniRef50_UPI00015B62A7 Cluster: PREDICTED: similar to cytochrome... 117 7e-25 UniRef50_Q70AR8 Cluster: Putative cytochrome P450; n=1; Streptom... 117 7e-25 UniRef50_Q26HX2 Cluster: Cytochrome P450 hydroxylase; n=1; Flavo... 117 7e-25 UniRef50_Q52S21 Cluster: Cytochrome P450; n=3; Plutella xylostel... 117 7e-25 UniRef50_A0NGH0 Cluster: ENSANGP00000031109; n=7; Culicidae|Rep:... 117 7e-25 UniRef50_UPI0000E48D2E Cluster: PREDICTED: similar to MGC64404 p... 117 9e-25 UniRef50_UPI0000E46433 Cluster: PREDICTED: similar to Cytochrome... 117 9e-25 UniRef50_A1WAC7 Cluster: Cytochrome P450; n=1; Acidovorax sp. JS... 117 9e-25 UniRef50_Q9ASR3 Cluster: At2g46960/F14M4.21; n=7; core eudicotyl... 117 9e-25 UniRef50_Q013N6 Cluster: Cytochrome P450, putative; n=2; Ostreoc... 117 9e-25 UniRef50_Q8MTC8 Cluster: Cytochrome P450 monooxygenase CYP321A1;... 117 9e-25 UniRef50_A5JM35 Cluster: Cytochrome P450 Cyp6AU1; n=1; Bombyx mo... 117 9e-25 UniRef50_Q59990 Cluster: Putative cytochrome P450 120; n=8; Cyan... 117 9e-25 UniRef50_UPI000038CC01 Cluster: COG2124: Cytochrome P450; n=1; N... 116 1e-24 UniRef50_Q8YMU4 Cluster: Cytochrome P450; n=10; Cyanobacteria|Re... 116 1e-24 UniRef50_A6FMY4 Cluster: Cytochrome P450; n=12; Rhodobacterales|... 116 1e-24 UniRef50_Q31NH2 Cluster: Cytochrome P450; n=2; Synechococcus elo... 116 2e-24 UniRef50_Q17BD6 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 116 2e-24 UniRef50_UPI0000D561F4 Cluster: PREDICTED: similar to Cytochrome... 116 2e-24 UniRef50_Q89VZ9 Cluster: Bll0894 protein; n=13; Alphaproteobacte... 116 2e-24 UniRef50_Q82IV2 Cluster: Cytochrome P450 hydroxylase; n=2; Strep... 116 2e-24 UniRef50_A5FJE6 Cluster: Cytochrome P450; n=1; Flavobacterium jo... 116 2e-24 UniRef50_A7PQ75 Cluster: Chromosome chr18 scaffold_24, whole gen... 116 2e-24 UniRef50_Q5XNT3 Cluster: Cytochrome P450; n=2; Anopheles gambiae... 116 2e-24 UniRef50_Q5TCH5 Cluster: Cytochrome P450, family 4, subfamily A,... 116 2e-24 UniRef50_UPI00015B6167 Cluster: PREDICTED: similar to cytochrome... 115 3e-24 UniRef50_Q7SY18 Cluster: Zgc:63602; n=2; Danio rerio|Rep: Zgc:63... 115 3e-24 UniRef50_Q82IY3 Cluster: Pentalenene C13 hydroxylase; cytochrome... 115 3e-24 UniRef50_Q8KUI0 Cluster: Cytochrome P450; n=1; Actinosynnema pre... 115 3e-24 UniRef50_Q2Y711 Cluster: Cytochrome P450; n=1; Nitrosospira mult... 115 4e-24 UniRef50_A3VL14 Cluster: Possible cytochrome P450 hydroxylase su... 115 4e-24 UniRef50_A7RMN2 Cluster: Predicted protein; n=1; Nematostella ve... 115 4e-24 UniRef50_Q9VG82 Cluster: Probable cytochrome P450 9f2; n=26; End... 115 4e-24 UniRef50_Q603T8 Cluster: Cytochrome P450 51; n=1; Methylococcus ... 114 5e-24 UniRef50_A1ZWE3 Cluster: Cytochrome P450 family protein; n=1; Mi... 114 5e-24 UniRef50_A7SWV9 Cluster: Predicted protein; n=1; Nematostella ve... 114 5e-24 UniRef50_UPI00015B5C73 Cluster: PREDICTED: similar to cytochrome... 114 7e-24 UniRef50_UPI00003BFC2E Cluster: PREDICTED: similar to Probable c... 114 7e-24 UniRef50_Q6DHE1 Cluster: Zgc:109896 protein; n=20; Euteleostomi|... 114 7e-24 UniRef50_A4D937 Cluster: CrpE; n=1; Nostoc sp. ATCC 53789|Rep: C... 114 7e-24 UniRef50_A1ZZK3 Cluster: Cytochrome P450 4A10; n=1; Microscilla ... 114 7e-24 UniRef50_UPI000038DD76 Cluster: COG2124: Cytochrome P450; n=1; N... 113 9e-24 UniRef50_P13527 Cluster: Cytochrome P450 6A1; n=3; Musca domesti... 113 9e-24 UniRef50_UPI0000DB6D9C Cluster: PREDICTED: similar to Cytochrome... 113 1e-23 UniRef50_Q5W1K7 Cluster: Cytochrome P450 CYP6AY1 protein; n=3; H... 113 1e-23 UniRef50_UPI0000E49A50 Cluster: PREDICTED: hypothetical protein;... 113 2e-23 UniRef50_A1HDJ4 Cluster: Cytochrome P450; n=4; Burkholderiaceae|... 113 2e-23 UniRef50_Q82QD5 Cluster: Putative cytochrome P450 / NADPH-ferrih... 112 2e-23 UniRef50_UPI0000E473EA Cluster: PREDICTED: hypothetical protein;... 112 3e-23 UniRef50_UPI0000D56CEB Cluster: PREDICTED: similar to Probable c... 112 3e-23 UniRef50_A3Q0Q7 Cluster: Cytochrome P450 precursor; n=3; Mycobac... 112 3e-23 UniRef50_Q0NZP1 Cluster: Ent-kaurenoic acid 13-hydroxylase; n=2;... 112 3e-23 UniRef50_O48925 Cluster: CYP82C1p; n=5; core eudicotyledons|Rep:... 112 3e-23 UniRef50_Q9NB69 Cluster: Cytochrome P450 monooxygenase; n=2; Tri... 112 3e-23 UniRef50_UPI0000E49F6F Cluster: PREDICTED: similar to cytochrome... 111 4e-23 UniRef50_Q8YN84 Cluster: Cytochrome P450; n=4; cellular organism... 111 4e-23 UniRef50_Q1DEH2 Cluster: Cytochrome P450 family protein; n=1; My... 111 4e-23 UniRef50_A6G0E4 Cluster: Cytochrome P450 51; n=1; Plesiocystis p... 111 4e-23 UniRef50_A0YL42 Cluster: Cytochrome P450; n=2; Cyanobacteria|Rep... 111 4e-23 UniRef50_A5YU13 Cluster: CYP97C3; n=1; Chlamydomonas reinhardtii... 111 4e-23 UniRef50_Q4SQM7 Cluster: Chromosome 17 SCAF14532, whole genome s... 111 5e-23 UniRef50_Q56JT9 Cluster: Cytochrome P450 monooxygenase; n=10; En... 111 5e-23 UniRef50_Q3I415 Cluster: Cytochrome P450; n=1; Leptinotarsa dece... 111 5e-23 UniRef50_Q25176 Cluster: Cytochrome P-450; n=24; Ditrysia|Rep: C... 111 5e-23 UniRef50_A6S200 Cluster: Putative uncharacterized protein; n=1; ... 111 5e-23 UniRef50_Q9V9L1 Cluster: Probable cytochrome P450 6w1; n=3; Dros... 111 6e-23 UniRef50_UPI00015B5FEA Cluster: PREDICTED: similar to cytochrome... 110 8e-23 UniRef50_Q3E1G3 Cluster: Cytochrome P450; n=2; Chloroflexus|Rep:... 110 8e-23 UniRef50_A6G220 Cluster: Cytochrome P450; n=1; Plesiocystis paci... 110 8e-23 UniRef50_A4X8D8 Cluster: Cytochrome P450; n=5; Actinomycetales|R... 110 8e-23 UniRef50_A0YW07 Cluster: Cytochrome P450 hydroxylase; n=1; Lyngb... 110 8e-23 UniRef50_Q8T5C1 Cluster: Cytochrome P450 monooxygenase CYP6X1v1;... 110 8e-23 UniRef50_A7SF10 Cluster: Predicted protein; n=1; Nematostella ve... 110 8e-23 UniRef50_A6SDR2 Cluster: Cytochrome P450 52; n=2; Sclerotiniacea... 110 8e-23 UniRef50_UPI0000D5745C Cluster: PREDICTED: similar to Probable c... 110 1e-22 UniRef50_UPI000038CD69 Cluster: COG2124: Cytochrome P450; n=1; N... 110 1e-22 UniRef50_A5NX46 Cluster: Cytochrome P450; n=2; Alphaproteobacter... 110 1e-22 UniRef50_A1CS83 Cluster: NADPH cytochrome P450; n=1; Aspergillus... 110 1e-22 UniRef50_Q5UXK0 Cluster: Cytochrome P450; n=1; Haloarcula marism... 110 1e-22 UniRef50_UPI0000E49222 Cluster: PREDICTED: similar to CYP4BB1 is... 109 1e-22 UniRef50_Q121J8 Cluster: Cytochrome P450; n=2; Comamonadaceae|Re... 109 1e-22 UniRef50_Q9LUD2 Cluster: Cytochrome P450; n=6; core eudicotyledo... 109 1e-22 UniRef50_Q94EV6 Cluster: Cytochrome P450; n=19; Poaceae|Rep: Cyt... 109 1e-22 UniRef50_A5HKL8 Cluster: Cytochrome P450 CYP9A22; n=5; Ditrysia|... 109 1e-22 UniRef50_P30608 Cluster: Cytochrome P450 52A6; n=19; Saccharomyc... 109 1e-22 UniRef50_Q9Y6A2 Cluster: Cytochrome P450 46A1; n=22; Amniota|Rep... 109 1e-22 UniRef50_A6G6Z8 Cluster: Cytochrome P450; n=1; Plesiocystis paci... 109 2e-22 UniRef50_A0Y8J6 Cluster: Probable bifunctional P-450:NADPH-P450 ... 109 2e-22 UniRef50_Q2GUJ4 Cluster: Putative uncharacterized protein; n=2; ... 109 2e-22 UniRef50_Q0U771 Cluster: Putative uncharacterized protein; n=3; ... 109 2e-22 UniRef50_UPI0000D56E81 Cluster: PREDICTED: similar to Probable c... 109 2e-22 UniRef50_Q5KSN6 Cluster: Putative P450; n=1; Streptomyces sp. KO... 109 2e-22 UniRef50_A1W125 Cluster: Cytochrome P450 family protein; n=12; C... 109 2e-22 UniRef50_A2XB72 Cluster: Putative uncharacterized protein; n=2; ... 109 2e-22 UniRef50_A1DAX0 Cluster: Cytochrome P450; n=5; Trichocomaceae|Re... 109 2e-22 UniRef50_Q964Q7 Cluster: Cytochrome P450 6d3; n=9; Schizophora|R... 109 2e-22 UniRef50_Q9Y0E3 Cluster: Cytochrome P450; n=4; Culicidae|Rep: Cy... 108 3e-22 UniRef50_Q0GK98 Cluster: Cytochrome P450 CYP3-like member 4; n=3... 108 3e-22 UniRef50_Q9V675 Cluster: Probable cytochrome P450 6g2; n=2; Soph... 108 3e-22 UniRef50_Q4CB21 Cluster: Cytochrome P450; n=1; Crocosphaera wats... 108 4e-22 UniRef50_Q9SCP8 Cluster: Cytochrom P450-like protein; n=12; Magn... 108 4e-22 UniRef50_A5YU14 Cluster: CYP97A5; n=4; Chlorophyta|Rep: CYP97A5 ... 108 4e-22 UniRef50_UPI0000D577EE Cluster: PREDICTED: similar to Probable c... 107 6e-22 UniRef50_Q10ZS2 Cluster: Cytochrome P450; n=1; Trichodesmium ery... 107 6e-22 UniRef50_A7DAQ3 Cluster: Cytochrome P450; n=2; Methylobacterium ... 107 6e-22 UniRef50_A1XEM0 Cluster: CYP82E8; n=22; Nicotiana|Rep: CYP82E8 -... 107 6e-22 UniRef50_Q9BID3 Cluster: Cytochrome P450; n=2; Anopheles gambiae... 107 6e-22 UniRef50_UPI0000DB77A2 Cluster: PREDICTED: similar to Probable c... 107 8e-22 UniRef50_UPI0000DB76BC Cluster: PREDICTED: similar to Probable c... 107 8e-22 UniRef50_UPI0000D559EB Cluster: PREDICTED: similar to Probable c... 107 8e-22 UniRef50_Q8YQS3 Cluster: Cytochrome P450; n=7; Cyanobacteria|Rep... 107 8e-22 UniRef50_Q0S645 Cluster: Cytochrome P450 CYP136; n=4; Actinomyce... 107 8e-22 UniRef50_Q0DIA1 Cluster: Os05g0405500 protein; n=4; Oryza sativa... 107 8e-22 UniRef50_Q6JEK3 Cluster: 14a demethylase; n=1; Strongylocentrotu... 107 8e-22 UniRef50_Q0CI06 Cluster: Cytochrome P450 52; n=3; Aspergillus|Re... 107 1e-21 UniRef50_P82711 Cluster: Probable cytochrome P450 6a19; n=11; Dr... 107 1e-21 UniRef50_A4A9V8 Cluster: Cytochrome P450; n=4; Bacteria|Rep: Cyt... 106 1e-21 UniRef50_Q9VHP4 Cluster: Probable cytochrome P450 313b1; n=2; So... 106 1e-21 UniRef50_UPI0000DB7562 Cluster: PREDICTED: similar to Probable c... 106 2e-21 UniRef50_Q4BVN8 Cluster: Cytochrome P450; n=4; Cyanobacteria|Rep... 106 2e-21 UniRef50_Q9P493 Cluster: Cytochrome P-450 cyp509A1; n=1; Cunning... 106 2e-21 UniRef50_P24557 Cluster: Thromboxane-A synthase; n=40; Tetrapoda... 106 2e-21 UniRef50_P77900 Cluster: Putative cytochrome P450 132; n=8; Myco... 106 2e-21 UniRef50_UPI0000E4A8EA Cluster: PREDICTED: similar to GA15235-PA... 105 2e-21 UniRef50_Q0ASD0 Cluster: Cytochrome P450; n=1; Maricaulis maris ... 105 2e-21 UniRef50_A4S2Q7 Cluster: Predicted protein; n=2; Ostreococcus|Re... 105 2e-21 UniRef50_A3B3X2 Cluster: Putative uncharacterized protein; n=3; ... 105 2e-21 UniRef50_A2WPP2 Cluster: Putative uncharacterized protein; n=3; ... 105 2e-21 UniRef50_Q5XNT0 Cluster: Cytochrome P450; n=4; Culicidae|Rep: Cy... 105 2e-21 UniRef50_Q2UI50 Cluster: Cytochrome P450 CYP4/CYP19/CYP26 subfam... 105 2e-21 UniRef50_Q9V776 Cluster: Probable cytochrome P450 317a1; n=3; So... 105 2e-21 UniRef50_UPI0000E4A41F Cluster: PREDICTED: hypothetical protein;... 105 3e-21 UniRef50_A6FXD3 Cluster: Cytochrome P450 family protein; n=1; Pl... 105 3e-21 UniRef50_Q4Q2L1 Cluster: Cytochrome p450-like protein; n=4; Leis... 105 3e-21 UniRef50_Q1ZXL9 Cluster: Cytochrome P450 family protein; n=2; Di... 105 3e-21 UniRef50_P0A513 Cluster: Cytochrome P450 51; n=19; Corynebacteri... 105 3e-21 UniRef50_Q1I2J9 Cluster: Putative cytochrome P450; n=1; Pseudomo... 105 4e-21 UniRef50_P98186 Cluster: Cytochrome P450; n=1; Rhipicephalus mic... 105 4e-21 UniRef50_Q5B6B3 Cluster: Cytochrome P450 52; n=5; Eurotiomycetid... 105 4e-21 UniRef50_Q4H2B4 Cluster: Cytochrome P450 monooxygenase; n=2; Bas... 105 4e-21 UniRef50_A7F687 Cluster: Putative uncharacterized protein; n=2; ... 105 4e-21 UniRef50_Q9VS78 Cluster: Probable cytochrome P450 316a1; n=2; So... 105 4e-21 UniRef50_A6GCY6 Cluster: Cytochrome P450; n=1; Plesiocystis paci... 104 5e-21 UniRef50_A4BWJ8 Cluster: Cytochrome P450; n=6; Bacteroidetes|Rep... 104 5e-21 UniRef50_Q9LXX7 Cluster: Cytochrome P450-like protein; n=8; Magn... 104 5e-21 UniRef50_Q54ZM4 Cluster: Cytochrome P450 family protein; n=2; Di... 104 5e-21 UniRef50_Q5AR62 Cluster: Putative uncharacterized protein; n=1; ... 104 5e-21 UniRef50_A4BAW7 Cluster: Possible cytochrome P450 family protein... 104 7e-21 UniRef50_Q9LUC8 Cluster: Cytochrome P450; n=84; Magnoliophyta|Re... 104 7e-21 UniRef50_Q5XNU3 Cluster: Cytochrome P450; n=7; Culicidae|Rep: Cy... 104 7e-21 UniRef50_A7S7K8 Cluster: Predicted protein; n=1; Nematostella ve... 104 7e-21 UniRef50_O43174 Cluster: Cytochrome P450 26A1; n=40; Euteleostom... 104 7e-21 UniRef50_A6CJ44 Cluster: Cytochrome P450 hydroxylase; n=1; Bacil... 103 9e-21 UniRef50_Q10S04 Cluster: Cytochrome P450 family protein; n=9; Or... 103 9e-21 UniRef50_UPI00015B4ED4 Cluster: PREDICTED: similar to cytochrome... 103 1e-20 UniRef50_Q7SXE6 Cluster: LOC402831 protein; n=17; Euteleostomi|R... 103 1e-20 UniRef50_Q8GBX2 Cluster: Cytochrome-P450-monooxygenase; n=1; Sor... 103 1e-20 UniRef50_Q1EDA8 Cluster: HctH; n=1; Lyngbya majuscula|Rep: HctH ... 103 1e-20 UniRef50_Q2HDU4 Cluster: Cytochrome P450 52; n=5; Pezizomycotina... 103 1e-20 UniRef50_UPI0000D9A6B6 Cluster: PREDICTED: similar to Cytochrome... 103 2e-20 UniRef50_Q5Z0Q8 Cluster: Cytochrome P450 monooxygenase; n=6; Cor... 103 2e-20 UniRef50_Q2J4I2 Cluster: Cytochrome P450; n=2; Frankia|Rep: Cyto... 103 2e-20 UniRef50_Q1GGM8 Cluster: Cytochrome P450; n=23; cellular organis... 103 2e-20 UniRef50_A3IXI8 Cluster: Cytochrome P450; n=1; Cyanothece sp. CC... 103 2e-20 UniRef50_A4R1C8 Cluster: Putative uncharacterized protein; n=1; ... 103 2e-20 UniRef50_A1D653 Cluster: Cytochrome P450 52; n=1; Neosartorya fi... 103 2e-20 UniRef50_Q9VRI9 Cluster: Probable cytochrome P450 6t1; n=1; Dros... 103 2e-20 UniRef50_UPI0000D56E84 Cluster: PREDICTED: similar to Probable c... 102 2e-20 UniRef50_Q09D70 Cluster: Putative cytochrome P450 135A1; n=1; St... 102 2e-20 UniRef50_Q9FHC0 Cluster: Cytochrome P-450-like protein; n=5; Mag... 102 2e-20 UniRef50_Q86QN2 Cluster: Cytochrome P450 CYP12F1; n=15; Culicida... 102 2e-20 UniRef50_Q3I417 Cluster: Cytochrome P450; n=4; Cucujiformia|Rep:... 102 2e-20 UniRef50_Q17GV0 Cluster: Cytochrome P450; n=4; Aedes aegypti|Rep... 102 2e-20 UniRef50_Q56VS2 Cluster: Cytochrome P450 monooxygenase pc-3; n=2... 102 2e-20 UniRef50_Q1DZ64 Cluster: Cytochrome P450 52; n=4; Eurotiomycetid... 102 2e-20 UniRef50_Q0LHR9 Cluster: Cytochrome P450; n=1; Herpetosiphon aur... 102 3e-20 UniRef50_Q5XM71 Cluster: Cytochrome P450; n=2; Anopheles gambiae... 102 3e-20 UniRef50_A0BYI6 Cluster: Chromosome undetermined scaffold_137, w... 102 3e-20 UniRef50_UPI00015B5A0F Cluster: PREDICTED: similar to cytochrome... 101 4e-20 UniRef50_Q0VLW6 Cluster: Cytochrome P450, putative; n=1; Alcaniv... 101 4e-20 UniRef50_A6FYS5 Cluster: Possible cytochrome P450 hydroxylase su... 101 4e-20 UniRef50_Q9FF18 Cluster: Cytochrome P450-like protein; n=9; Magn... 101 4e-20 UniRef50_A7Q635 Cluster: Chromosome undetermined scaffold_55, wh... 101 4e-20 UniRef50_Q2TZX1 Cluster: Cytochrome P450 CYP3/CYP5/CYP6/CYP9 sub... 101 4e-20 UniRef50_A1C9K9 Cluster: Cytochrome P450 52; n=1; Aspergillus cl... 101 4e-20 UniRef50_A6G8E6 Cluster: Cytochrome P450; n=1; Plesiocystis paci... 101 5e-20 UniRef50_Q93VK5 Cluster: At1g31800/68069_m00159; n=12; Magnoliop... 101 5e-20 UniRef50_A7PDZ0 Cluster: Chromosome chr11 scaffold_13, whole gen... 101 5e-20 UniRef50_A2YQ01 Cluster: Putative uncharacterized protein; n=3; ... 101 5e-20 UniRef50_Q27693 Cluster: Cytochrome P450; n=2; Musca domestica|R... 101 5e-20 UniRef50_Q16FQ2 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep... 101 5e-20 UniRef50_A6SJT7 Cluster: Cytochrome P450 52; n=2; Sclerotiniacea... 101 5e-20 UniRef50_Q9SD85 Cluster: Flavonoid 3'-monooxygenase; n=66; Magno... 101 5e-20 UniRef50_Q9VYT8 Cluster: Probable cytochrome P450 28c1; n=7; Sop... 101 5e-20 UniRef50_UPI00015B6122 Cluster: PREDICTED: similar to cytochrome... 101 7e-20 UniRef50_Q11B49 Cluster: Cytochrome P450; n=8; Rhizobiales|Rep: ... 101 7e-20 UniRef50_A5VF31 Cluster: Cytochrome P450; n=2; Sphingomonas|Rep:... 101 7e-20 UniRef50_A1ZCF9 Cluster: Cytochrome P450, putative; n=1; Microsc... 101 7e-20 UniRef50_Q7Y222 Cluster: Putative cytochrome p450; n=1; Arabidop... 101 7e-20 UniRef50_A7S334 Cluster: Predicted protein; n=3; Nematostella ve... 101 7e-20 UniRef50_Q8NJK3 Cluster: Cytochrome P450 monooxygenase pc-2; n=7... 101 7e-20 UniRef50_A6S9P2 Cluster: Cytochrome P450 52; n=2; Sclerotiniacea... 101 7e-20 UniRef50_A4RFM7 Cluster: Putative uncharacterized protein; n=1; ... 101 7e-20 UniRef50_O48927 Cluster: Cytochrome P450 78A3; n=7; core eudicot... 101 7e-20 UniRef50_UPI00015B5A10 Cluster: PREDICTED: similar to cytochrome... 100 9e-20 UniRef50_UPI0000E46525 Cluster: PREDICTED: similar to cytochrome... 100 9e-20 UniRef50_Q2L6E2 Cluster: P450; n=1; Streptomyces sp. KO-3988|Rep... 100 9e-20 UniRef50_Q50EK3 Cluster: Cytochrome P450 CYPD; n=5; Spermatophyt... 100 9e-20 UniRef50_Q0D4C4 Cluster: Os07g0635300 protein; n=10; Oryza sativ... 100 9e-20 UniRef50_Q0UKV8 Cluster: Putative uncharacterized protein; n=1; ... 100 9e-20 UniRef50_Q9AXM6 Cluster: Taxane 10-beta-hydroxylase; n=16; Eukar... 100 9e-20 UniRef50_Q16850 Cluster: Cytochrome P450 51A1; n=36; Euteleostom... 100 9e-20 UniRef50_UPI00015B569B Cluster: PREDICTED: similar to cytochrome... 100 1e-19 UniRef50_Q0Z7A9 Cluster: Cytochrome p450; n=1; Synechococcus sp.... 100 1e-19 UniRef50_A6WEH8 Cluster: Cytochrome P450; n=1; Kineococcus radio... 100 1e-19 UniRef50_A2YMR4 Cluster: Putative uncharacterized protein; n=3; ... 100 1e-19 UniRef50_Q58QP8 Cluster: Cytochrome P450; n=1; Mayetiola destruc... 100 1e-19 UniRef50_A5JTS8 Cluster: Cytochrome P450; n=7; Ditrysia|Rep: Cyt... 100 1e-19 UniRef50_A7F1G0 Cluster: Putative uncharacterized protein; n=1; ... 100 1e-19 UniRef50_A4RLQ3 Cluster: Cytochrome P450 52; n=1; Magnaporthe gr... 100 1e-19 UniRef50_A7PEY9 Cluster: Chromosome chr11 scaffold_13, whole gen... 99 2e-19 UniRef50_A7RT69 Cluster: Predicted protein; n=1; Nematostella ve... 99 2e-19 UniRef50_Q2HFV6 Cluster: Putative uncharacterized protein; n=1; ... 99 2e-19 UniRef50_A1CK35 Cluster: Fatty acid hydroxylase, putative; n=7; ... 99 2e-19 UniRef50_Q9V6H1 Cluster: Probable cytochrome P450 9h1; n=3; Soph... 99 2e-19 UniRef50_Q08QP6 Cluster: Cytochrome P450; n=1; Stigmatella auran... 100 2e-19 UniRef50_A3ADU7 Cluster: Putative uncharacterized protein; n=3; ... 100 2e-19 UniRef50_A0A8M4 Cluster: Cytochrome P450 314 family; n=1; Daphni... 100 2e-19 UniRef50_Q2UT03 Cluster: Cytochrome P450 52; n=6; Trichocomaceae... 100 2e-19 UniRef50_P95099 Cluster: Putative cytochrome P450 136; n=15; Myc... 100 2e-19 UniRef50_UPI00015B595E Cluster: PREDICTED: similar to cytochrome... 99 3e-19 UniRef50_UPI0000D55B02 Cluster: PREDICTED: similar to Probable c... 99 3e-19 UniRef50_Q6NCP8 Cluster: Possible cytochrome P450 hydroxylase su... 99 3e-19 UniRef50_Q5YMA8 Cluster: Cytochrome P450 monooxygenase; n=1; Noc... 99 3e-19 UniRef50_Q39NW6 Cluster: Cytochrome P450; n=1; Burkholderia sp. ... 99 3e-19 UniRef50_A4FKX0 Cluster: Cytochrome P450; n=1; Saccharopolyspora... 99 3e-19 UniRef50_Q2LAK7 Cluster: Cytochrome P450 monooxygenase CYP72A67;... 99 3e-19 UniRef50_Q5ARQ0 Cluster: Putative uncharacterized protein; n=1; ... 99 3e-19 UniRef50_A1CIZ0 Cluster: Cytochrome P450; n=1; Aspergillus clava... 99 3e-19 UniRef50_A1C5L5 Cluster: Cytochrome P450 oxidoreductase, putativ... 99 3e-19 UniRef50_UPI000023DC99 Cluster: hypothetical protein FG02366.1; ... 99 4e-19 UniRef50_Q9LSF8 Cluster: Cytochrome p450; n=2; Arabidopsis thali... 99 4e-19 UniRef50_A5BGU6 Cluster: Putative uncharacterized protein; n=1; ... 99 4e-19 UniRef50_Q8WQN0 Cluster: Cytochrome P450 CYP6S2; n=6; Culicidae|... 99 4e-19 UniRef50_Q174T2 Cluster: Cytochrome P450; n=13; Aedes aegypti|Re... 99 4e-19 UniRef50_Q9VWR2 Cluster: Probable cytochrome P450 308a1; n=2; So... 99 4e-19 UniRef50_UPI00005842DC Cluster: PREDICTED: similar to CYP2A13 pr... 98 5e-19 UniRef50_A7PQ74 Cluster: Chromosome chr18 scaffold_24, whole gen... 98 5e-19 UniRef50_A1XEH2 Cluster: CYP82M1v1; n=5; Nicotiana tabacum|Rep: ... 98 5e-19 UniRef50_Q2TWI0 Cluster: Cytochrome P450 52; n=2; Pezizomycotina... 98 5e-19 UniRef50_UPI00015B480D Cluster: PREDICTED: similar to cytochrome... 98 6e-19 UniRef50_UPI00015B46F7 Cluster: PREDICTED: similar to Cyp6g1; n=... 98 6e-19 UniRef50_A7U483 Cluster: Cytochrome P450 family 17 polypeptide 2... 98 6e-19 UniRef50_Q9SJH2 Cluster: Putative cytochrome P450; n=1; Arabidop... 98 6e-19 UniRef50_Q9LN32 Cluster: F18O14.38; n=5; core eudicotyledons|Rep... 98 6e-19 UniRef50_Q22Z86 Cluster: Cytochrome P450 family protein; n=1; Te... 98 6e-19 UniRef50_A7SKW0 Cluster: Predicted protein; n=6; Nematostella ve... 98 6e-19 UniRef50_Q2U4F1 Cluster: Cytochrome P450; n=1; Aspergillus oryza... 98 6e-19 UniRef50_A2QLV1 Cluster: Contig An06c0110, complete genome; n=3;... 98 6e-19 UniRef50_Q9V674 Cluster: Cytochrome P450 6g1; n=16; Schizophora|... 98 6e-19 UniRef50_UPI000058466C Cluster: PREDICTED: similar to cytochrome... 97 8e-19 UniRef50_Q9ZW95 Cluster: F5A8.3 protein; n=1; Arabidopsis thalia... 97 8e-19 UniRef50_Q9SZ46 Cluster: Cytochrome P450-like protein; n=11; cor... 97 8e-19 >UniRef50_Q9VYY4 Cluster: Cytochrome P450 4g15; n=8; Neoptera|Rep: Cytochrome P450 4g15 - Drosophila melanogaster (Fruit fly) Length = 574 Score = 745 bits (1841), Expect = 0.0 Identities = 365/563 (64%), Positives = 432/563 (76%), Gaps = 30/563 (5%) Query: 16 SAINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRN 75 S ++FY LL+P ++LWY YWR+SR LY LA +L + + +G ++ +FR Sbjct: 12 SPSSVFYFLLLPTLVLWYIYWRLSRAHLYRLAGRLPGPRGLPIVGHLFDVIGPASSVFRT 71 Query: 76 IVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLL 135 +++KSA ++H + K+WIGP+L+VF+YDPRDVE++LSSHVYIDKA EY+FFKPWLG+GLL Sbjct: 72 VIRKSAPFEH--IAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKPWLGDGLL 129 Query: 136 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE-ASNFDCHDYMSECTV 194 ISTGQKWRSHRKLIAPTFHLNVLKSFI+LFN NSR VV KL+ E FDCHDYMSE TV Sbjct: 130 ISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGRTFDCHDYMSEATV 189 Query: 195 EILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKL 254 EILLETAMGVSK TQD+SGFEYAMAVM+MCDILH RH I+LR + +F T Y K Q +L Sbjct: 190 EILLETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYYKEQGRL 249 Query: 255 LDIIHGLTKKVIKRKKEEFASGKKPS-------------------NLNETATTS------ 289 L+IIHGLT KVI+ KK F G + S +++T +T+ Sbjct: 250 LNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKD 309 Query: 290 -EPSTGKLTSVEGLSFGQSSGLKXXXXXXXXX-GQKKRLAFLDLLLESSQSGVAISDEEI 347 E K + V GLS+GQS+GLK G+KKRLAFLDL+LES+Q+G I+D EI Sbjct: 310 REKDKEKASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLMLESAQNGALITDTEI 369 Query: 348 KEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMK 407 KEQVDTIMFEGHDTTAAGSSFFLS+MGIHQDIQD+V+ ELD IFGDS RP TFQDTLEMK Sbjct: 370 KEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQDTLEMK 429 Query: 408 YLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPN 467 YLERCLMETLR+YPPVP+IAR++ +++ L S IP G T+ +AT LHR P VY NPN Sbjct: 430 YLERCLMETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPN 489 Query: 468 KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKES 527 FDPDNFLPER ANRHYYAFVPFSAGPRSCVGRKYAMLKLK++LSTILRN+RV SDL ES Sbjct: 490 VFDPDNFLPERQANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTES 549 Query: 528 DFKLQADIILKRAEGFQVRLQPR 550 DFKLQADIILKR EGF+VRLQPR Sbjct: 550 DFKLQADIILKREEGFRVRLQPR 572 >UniRef50_Q9V3S0 Cluster: Cytochrome P450 4g1; n=62; Protostomia|Rep: Cytochrome P450 4g1 - Drosophila melanogaster (Fruit fly) Length = 556 Score = 508 bits (1254), Expect = e-142 Identities = 253/466 (54%), Positives = 331/466 (71%), Gaps = 12/466 (2%) Query: 89 VKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148 +K W+G LLVFL +P D+E+ILS H ++ KAEEYR+FKPW G+GLLIS G WR HRK+ Sbjct: 95 MKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGLLISNGHHWRHHRKM 154 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS-NFDCHDYMSECTVEILLETAMGVSKS 207 IAPTFH ++LKSF+ F +S+AVV ++ EA +FD HDYMS+ TV+ILL TAMGV K Sbjct: 155 IAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKL 214 Query: 208 TQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIK 267 + FEYA AV+ MCDI+H R K+ R D ++KFT + ++++II G+T KV+K Sbjct: 215 PEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVK 274 Query: 268 RKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLA 327 +KE F + + E +T ST + EGL G K+RLA Sbjct: 275 DRKENFQEESRA--IVEEISTPVAST-PASKKEGLRDDLDD------IDENDVGAKRRLA 325 Query: 328 FLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 LD ++E +++ + ++++I ++V+TIMFEGHDTT+AGSSF L MMGIH+DIQ KV E Sbjct: 326 LLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAE 385 Query: 387 LDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445 IFGD+ R TF DT+EMKYLER ++ETLRLYPPVP+IAR+++ ++ L S +P Sbjct: 386 QKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPK 445 Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505 GTT+++ Y +HRRPD+YPNP KFDPDNFLPER ANRHYY+F+PFSAGPRSCVGRKYAML Sbjct: 446 GTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAML 505 Query: 506 KLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 KLKV+LSTI+RN+ V S E+DFKLQADIILK GF V L+ R+ Sbjct: 506 KLKVLLSTIVRNYIVHSTDTEADFKLQADIILKLENGFNVSLEKRQ 551 >UniRef50_Q967Y5 Cluster: Cytochrome P450 CYP4G13v2; n=4; Neoptera|Rep: Cytochrome P450 CYP4G13v2 - Musca domestica (House fly) Length = 552 Score = 480 bits (1183), Expect = e-134 Identities = 245/535 (45%), Positives = 346/535 (64%), Gaps = 15/535 (2%) Query: 20 LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNA-LEFVGGSADIFRNIVQ 78 L V V + + Y Y+R + R Y+L D + N + F + I + + Q Sbjct: 24 LSLVFGVGVIAILYEYYRRNTRA-YKLMDTIPTPKQMPLIGNGHMAFGQNNHQILKLMSQ 82 Query: 79 KSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST 138 D V+I +G +VFL +P D+E+ L+ + +++K+ EYR+F+PW GNGLLIS Sbjct: 83 VFKDCGE--TVRILLGHMNVVFLTNPADLEIFLNGYKHLEKSVEYRYFQPWFGNGLLISK 140 Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKL-KKEASNFDCHDYMSECTVEIL 197 G WR HRK+IAPTFH ++LKSF+ F +S+AV + K FDCH YMSE TV+IL Sbjct: 141 GHHWRHHRKMIAPTFHQSILKSFVPTFVKHSKAVSGRFASKVGQEFDCHKYMSETTVDIL 200 Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257 L TAMG + + EYA AVM MCDI+H+R K++ R D +FT ++ KL+++ Sbjct: 201 LTTAMGCKVQPETEKSAEYAQAVMDMCDIIHIRQLKLFYRLDSTIRFTKLREHDNKLMNV 260 Query: 258 IHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXX 317 I +T+KV++ +K+ F + ++ ++ TA ++ K EGL Sbjct: 261 ILSMTRKVVEDRKKNF-NAEERGIVDRTAEDAKLKA-KAAKKEGLRDDLDD------IDE 312 Query: 318 XXXGQKKRLAFLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 376 G+K+RLA LD ++E ++ + +D+++ ++V+TIMFEGHDTTAAGSSF L M+GIH Sbjct: 313 NDIGEKRRLALLDAMMEMEKNPDIKWTDKDVMDEVNTIMFEGHDTTAAGSSFALCMLGIH 372 Query: 377 QDIQDKVIEELDQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEIT 435 QD+Q +V EE IFGD +R TF DTL+M YLER + ET RL+PPVP+IAR+ +++ Sbjct: 373 QDVQQRVFEEQQAIFGDDLNRDCTFADTLQMSYLERVICETQRLFPPVPLIARKAEEDVN 432 Query: 436 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495 L S I GTT+V+ Y +HRR D+YP+P KF+PDNFLPER+ANRHYYA++PFSAGPR Sbjct: 433 LKSGPYTIAKGTTVVLLQYFVHRRADIYPDPEKFNPDNFLPERTANRHYYAYIPFSAGPR 492 Query: 496 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 SCVGRK+AML+LKV+LSTI+RN+RV S + DF+LQ DIILK A GF + L+ R Sbjct: 493 SCVGRKFAMLQLKVLLSTIIRNYRVSSTRTQKDFQLQGDIILKMANGFNITLEKR 547 >UniRef50_Q16ML8 Cluster: Cytochrome P450; n=3; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 509 Score = 381 bits (938), Expect = e-104 Identities = 208/534 (38%), Positives = 306/534 (57%), Gaps = 37/534 (6%) Query: 22 YVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSA-DIFRNIVQKS 80 Y +LV + + W + R RL ++ DK+ F G ++F I +++ Sbjct: 9 YGILVFLIFAPFLQWWVKRARLVQIIDKIPGPKAYPFIGTTYTFFGKKHYELFYIIDERT 68 Query: 81 ADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQ 140 Y + +IW G R + + P VE I+ + +++K+ Y F WLG GLL S G+ Sbjct: 69 RRYP--DIHRIWTGMRPEIRISKPEYVETIIGASKHMEKSHGYDFLFDWLGEGLLTSKGE 126 Query: 141 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 197 +W HRKLI PTFH N+L F D+F + ++L+ A+ D ++++ ++I+ Sbjct: 127 RWFQHRKLITPTFHFNILDGFCDVFAEQGAVLAERLEPFANTGKPVDVFPFITKAALDII 186 Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257 ETAMGV + Q Y A+ +M +I R K WL P+ +FK T+Y + K LDI Sbjct: 187 CETAMGVKVNAQTGGENNYVNAIYRMSEIFVDRSIKPWLHPEFIFKRTEYGRQHKKALDI 246 Query: 258 IHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXX 317 +HG TKKVI+ +KE E STG + E L FG Sbjct: 247 VHGYTKKVIRDRKEALQ-------------VKENSTGAGDTGEDLYFGT----------- 282 Query: 318 XXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 377 KKRLAFLDLLLE + ++D++++E+VDT MFEGHDTT AG S+ L ++G+H Sbjct: 283 -----KKRLAFLDLLLEGNAKHKQLTDDDVREEVDTFMFEGHDTTTAGMSWALFLLGLHP 337 Query: 378 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 437 D QD+V +E+D IF SDRP T +D EMK LERCL ETLRLYP V R++++++TL Sbjct: 338 DWQDRVHQEIDSIFAGSDRPATMKDLGEMKLLERCLKETLRLYPSVSFFGRKLSEDVTL- 396 Query: 438 SNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 497 IPAGT + I Y +HR YP+P KFDPD FLPE + +RH +A++PFSAGPR+C Sbjct: 397 -GQYHIPAGTLMGIHAYHVHRDERFYPDPEKFDPDRFLPENTEHRHPFAYIPFSAGPRNC 455 Query: 498 VGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 +G+K+A+L+ K I+S++LR FRV S + K+ ++I + EG ++ L+ R+ Sbjct: 456 IGQKFAILEEKSIVSSVLRKFRVRSANTRDEQKICQELITRPNEGIRLYLEKRQ 509 >UniRef50_A0A8M5 Cluster: Cytochrome P450 4 family; n=1; Daphnia magna|Rep: Cytochrome P450 4 family - Daphnia magna Length = 526 Score = 369 bits (908), Expect = e-100 Identities = 189/468 (40%), Positives = 283/468 (60%), Gaps = 33/468 (7%) Query: 88 VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 147 +++ WIGP + F VE +LSS+ I K+ EY F PWL GLL STG KW++ RK Sbjct: 88 IIRAWIGPLPMFFATTAEAVEAVLSSNKIITKSREYDFLHPWLNTGLLTSTGSKWQTRRK 147 Query: 148 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS---NFDCHDYMSECTVEILLETAMGV 204 L+ P FH +L+ F+ +FN S +V+KL + + + + +++ CT++I+ ETAMG Sbjct: 148 LLTPAFHFKILEDFVHVFNEQSLILVNKLNQAVAKDKDLNIFPFVTLCTLDIICETAMGR 207 Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264 + Q ++ Y AV M ++ R + +L D +FK + + Q K L I+HG T K Sbjct: 208 NVEAQSKTDSAYVQAVYNMSQLIQHRQVRFYLWLDWMFKLSSHWPEQRKTLGILHGFTNK 267 Query: 265 VIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKK 324 VI+ + K + ++ +EPS E F K+ Sbjct: 268 VIQER--------KAEHQQRSSDIAEPSKDV---TEDAVFS-----------------KR 299 Query: 325 RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVI 384 RLAFLDLL+E SQ G +S +I+E+VDT MFEGHDTT+A ++ + ++G H ++Q+ V Sbjct: 300 RLAFLDLLIEFSQGGTVLSASDIREEVDTFMFEGHDTTSAAITWSIFLIGSHPEVQEMVN 359 Query: 385 EELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIP 444 EELD++FGDSDRP T D E+KYLE C+ E LRLYP VPII+R ++ + G +IP Sbjct: 360 EELDRVFGDSDRPATMADLSELKYLECCVKEALRLYPSVPIISRTCVEDTVI--GGDEIP 417 Query: 445 AGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAM 504 AGT++ I +Y LHR P +P+P + P FL E + RH Y++VPFSAGPR+C+G+++A+ Sbjct: 418 AGTSVSICSYYLHRDPKYFPDPELYQPKRFLAEHAERRHPYSYVPFSAGPRNCIGQRFAL 477 Query: 505 LKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552 ++ K +LS ILRNF V S K + L A++IL+ +G +VRL+P+K+ Sbjct: 478 MEEKAVLSAILRNFHVQSLDKREEIILLAELILRPRDGIRVRLEPKKK 525 >UniRef50_O76478 Cluster: Corpora allata cytochrome P450; n=2; Neoptera|Rep: Corpora allata cytochrome P450 - Diploptera punctata (Pacific beetle cockroach) Length = 497 Score = 347 bits (854), Expect = 3e-94 Identities = 191/493 (38%), Positives = 287/493 (58%), Gaps = 38/493 (7%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120 N+L G + FR + + + Y + + ++W+G R VFLY ++ IL+S VYIDK+ Sbjct: 39 NSLILRGTQEEFFRLLSKCATKYGN--IFRLWVGQRPFVFLYSAEAIQPILNSTVYIDKS 96 Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180 EY F PWLG GLL STG KW + RKL+ +FH VL+ F++ +S + ++L+ E Sbjct: 97 YEYSFLFPWLGTGLLTSTGNKWHTRRKLLTQSFHSKVLEDFLEPIYQHSLFLCNRLELEL 156 Query: 181 S--NFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRP 238 +F Y C ++I+ +TAMG + + Q+ S EY AV + +I+ R WL+P Sbjct: 157 DKPHFKVTPYAKLCALDIICDTAMGSTINAQENSQSEYVTAVDSLSEIVQRRFITPWLKP 216 Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTS 298 D LFK T K Q + L I+H T+KVI +KE+ + +NL Sbjct: 217 DFLFKMTKLGKKQEQCLKIVHNFTRKVINERKEDKL---RQNNLE--------------- 258 Query: 299 VEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEG 358 + Q +G+K +K RLA LDLLLE S++G ++DE+I E+VDT MF G Sbjct: 259 ---VEISQQNGIK----------KKHRLALLDLLLELSENGKVLTDEDICEEVDTFMFAG 305 Query: 359 HDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETL 417 HDT A+G S+ L ++G H D Q+K++EE + D+ T + ++ YLERC+ E + Sbjct: 306 HDTIASGVSWILYVLGHHLDSQEKIVEEFKNVMEEDNTEWPTMKHLNKLCYLERCIKEAM 365 Query: 418 RLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPE 477 RLYP VP+IAR + Q I + +P G T++I TY LHR +PNP+ F+PD FL Sbjct: 366 RLYPVVPLIARNLTQPIKIMDY--MLPEGVTILINTYLLHRDSRFFPNPDIFEPDRFLTS 423 Query: 478 RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIIL 537 R+ +A+VPFSAGPR+C+G+K+AM++LK+ILST+L+ F V S KE KL +++L Sbjct: 424 NCEARNPFAYVPFSAGPRNCIGQKFAMMELKIILSTVLQRFIVKSVDKEERLKLVGELVL 483 Query: 538 KRAEGFQVRLQPR 550 +G ++ + R Sbjct: 484 LNRDGIRLTITAR 496 >UniRef50_UPI00015B560A Cluster: PREDICTED: similar to cytochrome P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 543 Score = 335 bits (823), Expect = 2e-90 Identities = 194/540 (35%), Positives = 292/540 (54%), Gaps = 65/540 (12%) Query: 42 RLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFL 101 RLY + K NA F+G + DI Q+ D + S ++W+ RL + Sbjct: 30 RLYRESAKFPGPPALPFIGNAHFFMGSTEDILSKC-QELLD-TYPSPFRVWLADRLFYAV 87 Query: 102 YDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSF 161 YDP ++ I S I+K E Y+F +PWLG GL + KWR HRKLI PTF+ +L+SF Sbjct: 88 YDPEQLKTIFLSPKTIEKEELYKFAEPWLGTGLFTAPASKWRIHRKLIMPTFNPRILESF 147 Query: 162 IDLFNANSRAVVDKLKKE--ASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMA 219 +++F+ S ++ +++ E FD Y+S CT++I+ ETAMGV Q Q Y + Sbjct: 148 VEVFSVQSEVMIKEMEVELNGGEFDIFHYVSLCTLDIICETAMGVRSRAQTQRNSPYVES 207 Query: 220 VMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKP 279 ++ +I++ R KIWL PD++F T K+Q + + +H LT VIKRKK+ F Sbjct: 208 AKRLFEIVYSRMFKIWLHPDIIFNNTRLGKDQRECIKYVHSLTDDVIKRKKQAF------ 261 Query: 280 SNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSG 339 E T E GKL VEG KR AFLDLL+E S G Sbjct: 262 ----EGNGTVEGMNGKLPQVEG----------------------KRKAFLDLLMELSHEG 295 Query: 340 VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRP-- 397 +DEE++E+VDT+M G+DTTA + F + M+ H +IQDKV EEL +I+G D Sbjct: 296 TKFTDEELREEVDTMMIAGNDTTATVNCFVMLMLASHPEIQDKVYEELCEIYGSEDPSSV 355 Query: 398 -VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN----------------- 439 V +D M+YLER + ET+R++P P++ R+V ++ + ++ Sbjct: 356 LVRHEDLHRMEYLERVIKETMRIFPVGPVLVRRVTDDLNIGNHPLYFAIMNCNFDYINQI 415 Query: 440 -------GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 492 + G+++V+ K HR + + +P F+PD FLPE A RH Y ++PFSA Sbjct: 416 CFYGITGDYTLTKGSSVVLGIIKTHRSEEYWTDPLTFNPDRFLPEECAKRHPYTYIPFSA 475 Query: 493 GPRSCVGRKYAMLKLKVILSTILRNFRVISD--LKESDFKLQADIILKRAEGFQVRLQPR 550 GPR+C+G KYAM+ +K +L+T++R + + D L D KL+AD++LK E +R++ R Sbjct: 476 GPRNCLGMKYAMMAMKALLATVIRKYVIKKDNALPVQDIKLKADVMLKPVEPITIRIERR 535 >UniRef50_A7SWY9 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 509 Score = 327 bits (803), Expect = 5e-88 Identities = 178/496 (35%), Positives = 285/496 (57%), Gaps = 38/496 (7%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIG-PRLLVFLYDPRDVEVILSSHVYIDK 119 N LEF ++ I+ + + + + +W+ + + +Y+P+ VEVILSS +I K Sbjct: 46 NTLEFKDEPSEFLEQIMGWCSQF--KGIFCLWLSFAKPFLLIYEPKTVEVILSSSKHITK 103 Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE 179 A+ Y F PWLG GLL STG+KW+ R+LI PTFH +L F+ +F+ S+ +V +K + Sbjct: 104 AQFYDFLLPWLGTGLLTSTGEKWKKRRRLITPTFHFKILNDFVQVFDQQSQLMVSIIKSQ 163 Query: 180 ASN--FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLR 237 S+ F+ ++ C ++I+ +TAMGV+ + Q S EY V++M +++ R + W+ Sbjct: 164 PSDKVFNIFPLIACCALDIIGKTAMGVNINAQKNSSSEYVKGVIRMSELIQSRQKRPWVH 223 Query: 238 PDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLT 297 P L+ T+ + K++ +H T +VI + +E P +ET + E TG+ Sbjct: 224 PAFLYCLTNEGREHNKIIKFLHDFTNQVITERIQERLYS--PKEQDETEESDE-FTGR-- 278 Query: 298 SVEGLSFGQSSGLKXXXXXXXXXGQKKRL-AFLDLLLESSQSGVAISDEEIKEQVDTIMF 356 +K+RL AFLD+LL + +G I E ++E+VD MF Sbjct: 279 ------------------------RKRRLVAFLDMLLNAYDAG-EIDVEGVREEVDIFMF 313 Query: 357 EGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMET 416 EGHDTTAA ++ + ++G H D+Q K E+D+ F + +T +KYLE + ET Sbjct: 314 EGHDTTAAAMAWAVQLLGEHPDVQRKAQAEVDEFFATNSGKLTADSLKGLKYLECVIKET 373 Query: 417 LRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 476 LR++P VP R + +++ L G+ IP GT + + T LHR P+V+P+P KF+PD FLP Sbjct: 374 LRIFPSVPFFGRSLVEDLEL--EGRLIPKGTDVGVITIGLHRNPEVWPSPMKFNPDRFLP 431 Query: 477 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADII 536 E S RH YAFVPFSAG R+C+G+++A+L+ KV+L+ IL NF ++S K + K A++I Sbjct: 432 ENSEGRHPYAFVPFSAGSRNCIGQRFALLEEKVVLAYILHNFDIVSTEKSTKIKTCAELI 491 Query: 537 LKRAEGFQVRLQPRKR 552 + +G V L R++ Sbjct: 492 TRPRDGIFVSLTTREQ 507 >UniRef50_A0MNW4 Cluster: Cyp4M9; n=20; Obtectomera|Rep: Cyp4M9 - Bombyx mandarina (Wild silk moth) (Wild silkworm) Length = 505 Score = 313 bits (769), Expect = 7e-84 Identities = 174/495 (35%), Positives = 280/495 (56%), Gaps = 33/495 (6%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120 NAL+ + A++F + +K+A ++ + W + +Y P ++E I+SS +I K+ Sbjct: 42 NALDVILSPAELFA-LTRKNAT-QWPNLNRFWSFGIGALNIYGPDEIEAIISSTQHITKS 99 Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-E 179 Y F WL +GLL+STG KW+ RK++ P FH N LK F + NS+ + LK E Sbjct: 100 PVYNFLSDWLRDGLLLSTGTKWQKRRKILTPAFHFNTLKQFCVILEENSQRFTENLKDTE 159 Query: 180 ASNFDCHDYMSECTVEILLETAMGVSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRP 238 + + +SE T+ + ETAM ++ ++G Y A+ ++ + R +I Sbjct: 160 GKSINVVPAISEYTLHSICETAMRTQLGSETSEAGRSYKNAICELGNQFVHRLARIPPHN 219 Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTS 298 + ++ K Q + L+I+H TK+VI + + ++ +N ++ T Sbjct: 220 NFIYNLFTLGK-QNEHLNIVHSFTKRVI-KDRRQYIRRNGGNNFDDEKDTQADE------ 271 Query: 299 VEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEG 358 + F KK+ A LDLLL++ + G+ I + ++E++DT MFEG Sbjct: 272 -HSIYFN-----------------KKKTAMLDLLLKAERDGL-IDEIGVQEEIDTFMFEG 312 Query: 359 HDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLR 418 HDTTA G ++ + ++ H+ IQDK+IEELD+IFG+S R +D +M+YLERC+ E+LR Sbjct: 313 HDTTATGLTYCIMLIANHKSIQDKIIEELDEIFGESTRAADIEDLSKMRYLERCIKESLR 372 Query: 419 LYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPER 478 LYPPVP + R +++EI L NG +PAGT I + LHRR D++ +P FDPD FLP Sbjct: 373 LYPPVPSMGRILSEEINL--NGYTVPAGTYCHIQIFDLHRREDLFKDPLVFDPDRFLPHN 430 Query: 479 SANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILK 538 + RH YA++PFSAGPR+C+G+K+A+L++K +LS +LR + + K D K D++L+ Sbjct: 431 TEGRHPYAYIPFSAGPRNCIGQKFAILEMKSLLSAVLRRYNLYPITKPEDLKFVLDLVLR 490 Query: 539 RAEGFQVRLQPRKRM 553 E VR R ++ Sbjct: 491 TTEPVHVRFVKRNKV 505 >UniRef50_Q964T1 Cluster: Cytochrome P450 4c21; n=1; Blattella germanica|Rep: Cytochrome P450 4c21 - Blattella germanica (German cockroach) Length = 501 Score = 309 bits (758), Expect = 1e-82 Identities = 171/468 (36%), Positives = 256/468 (54%), Gaps = 37/468 (7%) Query: 85 HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144 ++ ++ + G R V + P +EV+L + IDKA Y F WLG GLL S+G KW Sbjct: 68 YKPLILWYFGNRPFVNISSPELIEVVLRNTQLIDKAFLYDLFHSWLGTGLLTSSGAKWHQ 127 Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAM 202 HRK+I PTFH ++L+ FI +F S +V KL+KE F Y+S C ++I+ ETAM Sbjct: 128 HRKIITPTFHFSILEGFITIFAEKSEILVRKLQKEVGRGPFFIRQYVSNCALDIICETAM 187 Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262 G S + QD+ EY A+ KM D+L R L P+ +FK T Y K L +++G Sbjct: 188 GTSVNAQDEGFSEYVTAINKMTDVLSDRMANPLLYPEFIFKLTPYYWTHKKCLKVLNGFV 247 Query: 263 KKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQ 322 K+I+ +KEE +K S + +T+ E G+ + Sbjct: 248 NKIIQERKEE----RKKSKVTQTS-------------EDADIGKKKRVPFLDTLLDASED 290 Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 +L D+L E V T MFEGHDT +A ++ L +G H +IQ++ Sbjct: 291 DNKLTDTDILEE----------------VHTFMFEGHDTVSAAMTWLLFELGHHPEIQEE 334 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 +E+ IF SDR T D M YLER + E+LRL+P V R+ +Q+ L G Sbjct: 335 AYKEVQDIFQGSDRVPTMADLNNMNYLERVIKESLRLHPSVIYFVREAHQDFEL--GGYT 392 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 IPAGT + + +HR P+++PNP F+PDNFLP+R NRH YA++PFSAGPR+C+G+++ Sbjct: 393 IPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVNRHPYAYIPFSAGPRNCIGQRF 452 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 A+L+ KV+LS +LR++R + K D K + ++I + Q+ ++ R Sbjct: 453 ALLEEKVVLSYLLRHYRFRTVNKREDSKFKLEMINTPVKPIQLIIEAR 500 >UniRef50_Q6VAB7 Cluster: Cytochrome P450 CYP4AB2; n=6; Apocrita|Rep: Cytochrome P450 CYP4AB2 - Solenopsis invicta (Red imported fire ant) Length = 511 Score = 308 bits (755), Expect = 3e-82 Identities = 169/458 (36%), Positives = 264/458 (57%), Gaps = 36/458 (7%) Query: 98 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNV 157 LVF+ P D+E+IL++ +I K+ Y +PWLG GLL S G KW RK++ PTFH N+ Sbjct: 78 LVFIRHPDDLEIILNNTKHISKSNLYDALRPWLGMGLLTSGGSKWHLRRKILTPTFHFNI 137 Query: 158 LKSFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMGVSKSTQDQSGFE 215 L+ F+++ ++ LK D ++SE T+ + ETAMG S + Sbjct: 138 LQQFVEILIEEGESMTRSLKNAGGTITKDLVPFISEYTLNAICETAMGTSLQEMGSFQQQ 197 Query: 216 YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKE--EF 273 Y AV +M ++L R + WL+ D +F T + Q KLL I+HG T+KVI ++K+ + Sbjct: 198 YRKAVHRMGELLVYRAMRPWLKYDWIFSLTSKGREQKKLLKILHGFTEKVIAKRKDYHKR 257 Query: 274 ASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLL 333 G+ NLN+ +E T G+K KKR A LDLL+ Sbjct: 258 TKGQYLKNLNKDVVPNETET--------------IGIK-----------KKRFAMLDLLI 292 Query: 334 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 393 ++SQ G+ ++D +I+E+VDT MFEG DTT F LS++ H+DIQD V +E+D + + Sbjct: 293 QASQEGL-LTDFDIREEVDTFMFEGFDTTGMAMCFILSLLAEHKDIQDCVRKEIDAVMQE 351 Query: 394 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIAT 453 + + + +++YLERC+ E LRLYP V I+R ++E L + IPAGT +++ Sbjct: 352 NQGKLNMKSLQDLQYLERCIKEALRLYPSVYFISRITSEETELKT--YLIPAGTLVILNF 409 Query: 454 YKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILST 513 Y HR + +PNP FDPD FLP+ NRH Y+++PFSAGPR+C+G+++A+L+LK +L Sbjct: 410 YITHRDSNFWPNPEVFDPDRFLPDNIRNRHPYSYLPFSAGPRNCIGQRFALLELKAMLVP 469 Query: 514 ILRNFRV--ISDLKESDFKLQADIILKRAEGFQVRLQP 549 ++ NF + + L+ F + D+IL+ + +++ P Sbjct: 470 LIYNFYLEPVDYLENQRFGI--DMILRSLDPCRLKFVP 505 >UniRef50_Q27589 Cluster: Cytochrome P450 4d2; n=8; Acalyptratae|Rep: Cytochrome P450 4d2 - Drosophila melanogaster (Fruit fly) Length = 501 Score = 306 bits (752), Expect = 8e-82 Identities = 173/496 (34%), Positives = 280/496 (56%), Gaps = 43/496 (8%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120 N L + G + + V+K+ + + ++WI +L VF DPRD+E +LSS +I K Sbjct: 42 NLLMYRGLDPEQIMDFVKKN-QRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKN 100 Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180 Y+ WLG+GLL+STG+KW RK+I PTFH +L+ F+++F+ S +V++L+ A Sbjct: 101 NLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRA 160 Query: 181 SN---FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLR 237 + + ++I+ ETAMG + Q Y AV + +IL R W R Sbjct: 161 DGKTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQR 220 Query: 238 PDLLFKFTD--YAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGK 295 D +F+ T AK Q K + ++H T+ +I+ ++E + N TT E Sbjct: 221 VDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVN-------NSKETTPE----- 268 Query: 296 LTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIM 355 E ++F GQK+R+A LD+LL+S+ G +SDE+I+E+VDT M Sbjct: 269 ----EEVNF---------------LGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFM 309 Query: 356 FEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLM 414 FEGHDTT + SF L + H ++Q ++ +E+ + G D PVT +D E+K++E + Sbjct: 310 FEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIK 369 Query: 415 ETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNF 474 E+LRL+PPVP+I R +++ + GK IPAGT + + L R P+ + +P++F P+ F Sbjct: 370 ESLRLHPPVPMIGRWFAEDVEI--RGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERF 427 Query: 475 LPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 534 + H YA++PFSAGPR+C+G+K+AML++K +S +LR+F ++ E + + Sbjct: 428 DAD-VPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSM--N 484 Query: 535 IILKRAEGFQVRLQPR 550 I+L+ A G + L+PR Sbjct: 485 IVLRSANGVHLGLKPR 500 >UniRef50_UPI00015B5D09 Cluster: PREDICTED: similar to cytochrome P450 CYP4AB2; n=4; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis Length = 519 Score = 300 bits (737), Expect = 5e-80 Identities = 157/472 (33%), Positives = 264/472 (55%), Gaps = 24/472 (5%) Query: 82 DYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQK 141 D + + KIW + ++ + P DVE +L+S +I+K+ Y PW G GLL STG K Sbjct: 62 DKQYYPIYKIWTTHKAVIVILHPDDVETLLTSMEHIEKSIMYDMVHPWFGTGLLTSTGAK 121 Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD-CHDYMSECTVEILLET 200 W+ RK++ P FH +VL+ + D+ N+ V+ LK S + + ++ T++++ ET Sbjct: 122 WQKRRKILTPAFHFHVLQKYFDIIVENNEKVMHSLKSNGSVINNLVELLTYYTLDVICET 181 Query: 201 AMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHG 260 AMG + ++ +Y + + + + R + W + D F++T A+ Q K L++IHG Sbjct: 182 AMGTTLLDKEHQQ-KYRNVLHDVSNAVIYRLMRPWFQVDWTFRWTSVAEKQKKALEVIHG 240 Query: 261 LTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXX 320 +KK+IK +KE + K LN+ S+ S K E + Sbjct: 241 FSKKIIKERKE-YHEKTKGHYLNQLE--SDQSDDKKEDEEYFGY---------------- 281 Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 +KKRLA LDLL+ + G I D I+E+VDT +FEGHDT+A F + ++ H D+Q Sbjct: 282 -RKKRLAMLDLLIAKQKDGNQIDDAGIREEVDTFIFEGHDTSAMAMCFAILLIAEHNDVQ 340 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 D++ E+ ++ S+ + + ++ YLE C+ E+LRLYP VP I+R V +++ L Sbjct: 341 DRIRAEVKEVLEKSEGKMGVPEIQQLNYLELCIKESLRLYPSVPFISRGVTKDLHL--KN 398 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +P GT + I + LHR P+ +P+P KFDPD FLP+R RH Y+++PFSAGPR+C+G+ Sbjct: 399 YIVPKGTLIQINIFSLHRDPNFWPDPEKFDPDRFLPDRFQGRHPYSYIPFSAGPRNCIGQ 458 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552 K+AM++LK ++ ++ F + + + D++L+ A ++ R++ Sbjct: 459 KFAMMELKAFIAHLISEFYLEPIDLAHEVLITPDLVLRPARPVKLLFNERQQ 510 >UniRef50_Q9Y1T8 Cluster: Cytochrome P450 4W1; n=3; Arthropoda|Rep: Cytochrome P450 4W1 - Boophilus microplus (Cattle tick) Length = 549 Score = 299 bits (734), Expect = 1e-79 Identities = 169/489 (34%), Positives = 267/489 (54%), Gaps = 37/489 (7%) Query: 69 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP 128 S +F+ S Y + + + + ++ L+ VE +L+S+ + K EY KP Sbjct: 85 STHLFQVAFGFSRIYKNHGMFRFYDATHPVLVLFKAEAVEELLTSNTVLKKGHEYELIKP 144 Query: 129 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCH-- 186 WLG GLL S+G KWRS RKL+ P FH +L+ F+ N S +V KL + + C+ Sbjct: 145 WLGTGLLTSSGSKWRSRRKLLTPAFHFRILEDFLPAVNDQSNILVRKLGQLGKDRSCNIV 204 Query: 187 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLR-HTKI-WLRPDLLFKF 244 ++ C ++I+ ET MG + + Q EY A+ + R T + W+ D +F+ Sbjct: 205 PLVTLCALDIICETIMGYTINAQSNQDSEYVQAIKVLGHSFTRRLETPLYWI--DAIFQL 262 Query: 245 TDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKK-PSNLNETATTSEPSTGKLTSVEGLS 303 + + + + +H T KVI+ +K E S + + ETA+ S+ Sbjct: 263 SKPGREFARKVKELHQFTLKVIRERKREILSCPELQESYEETASESDVY----------- 311 Query: 304 FGQSSGLKXXXXXXXXXGQKKRLAFLDLLL-ESSQSGVAISDEEIKEQVDTIMFEGHDTT 362 GLK R FLD+LL E + ++E ++E+VDT MFEGHDTT Sbjct: 312 -----GLKGTA----------RKPFLDILLREHIKDPENFTEEHVREEVDTFMFEGHDTT 356 Query: 363 AAGSSFFLSMMGIHQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYP 421 A G S+ + ++ +H + QD + +ELD IFG D RPVT +D +MKY+E CL E+ RLYP Sbjct: 357 AMGMSWAIYLIALHTEHQDLIHQELDTIFGSDKTRPVTSEDLKQMKYMECCLKESQRLYP 416 Query: 422 PVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSAN 481 VP I+R+ ++ + G+K+P GT + +A Y LH V+P P++F PD F PE Sbjct: 417 SVPFISRKCEEDAVIC--GRKVPKGTDIQVAIYNLHHDEQVFPKPDEFRPDRFFPENVRG 474 Query: 482 RHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAE 541 RH +AFVPFSAGPR+C+G+++AM++ KV+++ ILRN+++++ + A+++L+ Sbjct: 475 RHAFAFVPFSAGPRNCIGQRFAMMEEKVVIANILRNYKLVALHYRDKIHVMAELVLRPTS 534 Query: 542 GFQVRLQPR 550 G V PR Sbjct: 535 GLHVIFIPR 543 >UniRef50_UPI00015B569D Cluster: PREDICTED: similar to cytochrome P450 CYP4C39; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4C39 - Nasonia vitripennis Length = 510 Score = 277 bits (680), Expect = 4e-73 Identities = 170/470 (36%), Positives = 257/470 (54%), Gaps = 40/470 (8%) Query: 87 SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146 +V +W+G + V + P +EV+L+S V I K+ Y PWLG+GLL TG+KW HR Sbjct: 72 NVYIMWLGMQPYVNIQKPHHMEVLLTSTVNIKKSSIYNIIIPWLGDGLLTLTGKKWHHHR 131 Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN-----FDCHDYMSECTVEILLETA 201 +L+ P FH VL+ F + + + + LK++ S+ D + S T++++ +TA Sbjct: 132 RLLTPAFHFRVLEQFTETMHEKADVFNECLKEQVSSNPKEPVDIFSFASRFTLDVICKTA 191 Query: 202 MGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261 MG+ Q S Y +V +M + R+ LRP + +D+ ++T+ G Sbjct: 192 MGIDMDAQRGSMNLYTKSVNQMSRFVVNRY----LRP---WYASDFIYSKTE-----DGK 239 Query: 262 TKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXG 321 + E++S L+E KL S + G+K Sbjct: 240 QSQAAISVMREYSSKVIKERLDERR--------KLKSSKDEDKEDEFGIK---------- 281 Query: 322 QKKRLAFLDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 ++ AFLDLLLE+S++ +S++E++ +VDT MF GHDTTA SF L ++G H DIQ Sbjct: 282 -QRNKAFLDLLLEASENDKNPLSNDELRNEVDTFMFAGHDTTATAISFTLLLLGNHLDIQ 340 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 KV EEL +F D D+P D ++KYL+R + ETLRLYP P R + ++ + Sbjct: 341 KKVHEELQTVFNNDVDKPTRAADLSQLKYLDRVIKETLRLYPSAPSFLRTLVEDTIF--D 398 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G I G+ ++I Y +HR P V+ NP FDPD FLPE +RH YA++PFSAGPR+C+G Sbjct: 399 GHTICKGSVIIINAYDMHRDPKVWENPTVFDPDRFLPENVRSRHPYAYIPFSAGPRNCIG 458 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549 +K+AML+LK+ L+ ILR +RV SD + KL IIL+ + +V P Sbjct: 459 QKFAMLELKIALTAILRKWRVKSDTLPENLKLLHSIILRCNKPIKVYFTP 508 >UniRef50_Q9NB96 Cluster: P450 CYP319A1; n=2; Parasitiformes|Rep: P450 CYP319A1 - Boophilus microplus (Cattle tick) Length = 531 Score = 275 bits (674), Expect = 2e-72 Identities = 155/474 (32%), Positives = 245/474 (51%), Gaps = 28/474 (5%) Query: 83 YDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKW 142 Y E ++G R + +Y VEV L++ K+ Y WL GLL S G KW Sbjct: 80 YQKEGFFAFYLGTRPCITIYKAEHVEVFLNNRHTQSKSIHYELLHSWLRTGLLTSAGPKW 139 Query: 143 RSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLET 200 +S R+++ P FH +L+ F+ N +R ++ D + C +++LLET Sbjct: 140 KSRRRMLTPAFHFKILEDFVAPMNKMARLTAARITDRIKEPWIDVVPMAAACALDVLLET 199 Query: 201 AMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHG 260 MGV+ + Y V + + + R WL D L+ T+ + K + IH Sbjct: 200 IMGVTNTNDGGESQRYVKNVNSVAERMVRRSQAPWLVLDCLYYRTEDGRQYQKNVSAIHA 259 Query: 261 LTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXX 320 T KVI +++EE + +N + T LT G +F Sbjct: 260 FTTKVISKRREEIINEIHAANSKKDNTPKMDEDFHLT---GRTF---------------- 300 Query: 321 GQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 KRL F+D+LL S + ++ ++I+E+VDT MFEGHDTTA G ++ L M+ H + Sbjct: 301 ---KRLTFIDILLRYSIEVDSTLTTDDIREEVDTFMFEGHDTTAMGIAWSLYMIASHHHV 357 Query: 380 QDKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438 Q K+ +ELD + D D +T + E+KY +R L E RL+P VP+I R +++I+L Sbjct: 358 QAKIHKELDSVLQSDLDADITLEKIKELKYFDRVLKECQRLFPSVPVIGRATSEDISLGK 417 Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 + +PA + + I Y LHR +P+P FDPD FLPE + YA+VPFSAGPR+C+ Sbjct: 418 H--VVPADSDVDIFIYALHRDQVCFPDPEVFDPDRFLPENVVHPAPYAYVPFSAGPRNCI 475 Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552 G++YA++++K+I++TILR F + + + L +++L+ G +V PR R Sbjct: 476 GQRYALMEVKIIVATILRRFTLEAVDQRDQLMLACELVLRPLNGLKVSFTPRSR 529 >UniRef50_UPI00015B604A Cluster: PREDICTED: similar to cytochrome P450 CYP4AB2; n=8; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis Length = 519 Score = 271 bits (665), Expect = 3e-71 Identities = 164/505 (32%), Positives = 261/505 (51%), Gaps = 29/505 (5%) Query: 40 RRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLV 99 + R EL DK+ N L F N++ + + ++ + K W+GP V Sbjct: 28 KSRSKELLDKIPGPPTVPILGNLLMFNVPIGKKTWNVI-RDLNKNYYPIAKFWLGPYPYV 86 Query: 100 FLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLK 159 ++ P D+E++LSS +++K Y PWL GLL S+G KW+ RK++ P FH +L+ Sbjct: 87 SIHHPDDLEILLSSTKHLEKGSAYTVLHPWLRTGLLTSSGSKWQQRRKILTPAFHFKILR 146 Query: 160 SFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMGVSKSTQDQS-GFEY 216 ++D+ N + + ++ L+ E S + S T+ I+ ETAMG++ D EY Sbjct: 147 KYMDITNEHGKKFIEALRTENSETVQSLMPFCSNYTLHIICETAMGIALDKIDTKISKEY 206 Query: 217 AMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASG 276 AV DI +L ++ +RP Y K L G + R +F Sbjct: 207 KNAV---ADIANLIMYRV-MRP--------YLKEWMMLPVWTFGRLQTQTLRTLHKFT-- 252 Query: 277 KKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESS 336 +T T K + + L G G KK+LA LDLLL ++ Sbjct: 253 -------KTVLTERREYHKRSDNKYLK-GFHDDTYDVNKDDVAIGGKKKLAMLDLLLSAA 304 Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396 Q G+ DE IKE+VDT MF GHDTT + + ++ H++IQ+K E+ ++ +S+ Sbjct: 305 QDGLT-DDEGIKEEVDTFMFAGHDTTGIALVYAIMLLAEHKEIQEKARAEVIEVLTESNG 363 Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456 + + ++ YLERC+ E+LR++PPV ++R V ++I L + +PAGT + + L Sbjct: 364 EIGTLEIQKLHYLERCIKESLRIFPPVSALSRTVKEDIQLKNY--VVPAGTEIGCHIFDL 421 Query: 457 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 516 HR P+ +P P K+DPD FLPE RH YA++PFSAG R+C+G+K+AM++LK + + IL Sbjct: 422 HRDPNFWPEPEKYDPDRFLPENIQGRHPYAYIPFSAGSRNCIGQKFAMMELKSLTARILY 481 Query: 517 NFRVISDLKESDFKLQADIILKRAE 541 NF + + D KL D++ + E Sbjct: 482 NFELEPVSQTKDMKLTLDLVTRPLE 506 >UniRef50_Q9VA27 Cluster: Cytochrome P450 4c3; n=15; Coelomata|Rep: Cytochrome P450 4c3 - Drosophila melanogaster (Fruit fly) Length = 535 Score = 262 bits (643), Expect = 1e-68 Identities = 112/231 (48%), Positives = 175/231 (75%), Gaps = 3/231 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G+KKRLAFLDLL+++S+ G +S+E+I+E+VDT MFEGHDTT+A S+ L ++G H + Q Sbjct: 306 GKKKRLAFLDLLIDASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQ 365 Query: 381 DKVIEELDQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 ++V+EELD IFGD + P T ++ ++M+YLE C+ ++LRL+P VP++AR V +++ + Sbjct: 366 ERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNI--G 423 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 GK +PAGT +I TY LHR P V+P P +F+PDNFLPE A RH +A++PFSAGPR+C+G Sbjct: 424 GKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIG 483 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +K+A+L+ K ++ST+LR +++ + + D L ++IL+ +G +V++ PR Sbjct: 484 QKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVKITPR 534 Score = 163 bits (396), Expect = 1e-38 Identities = 87/277 (31%), Positives = 141/277 (50%), Gaps = 4/277 (1%) Query: 23 VLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSAD 82 V L+ +++++ + R RL + +K+ NA+E ++F ++ Sbjct: 31 VFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVIGMQKL 90 Query: 83 YDHE-SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQK 141 + + ++W G V L++P VE IL+S +++K+ +Y + PWLG GLL ST +K Sbjct: 91 WGTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRK 150 Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLE 199 W S RK++ P FH +L FID+FN S + KL E + F+ Y++ CT++I+ E Sbjct: 151 WHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNLFPYVTLCTLDIVCE 210 Query: 200 TAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 259 TAMG Q S EY AV + I+ R KIWL+ D +F T K ++ +H Sbjct: 211 TAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLH 270 Query: 260 GLTKKVIKRKKEEFA-SGKKPSNLNETATTSEPSTGK 295 G + VI+ +K E A + +N N A + GK Sbjct: 271 GFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGK 307 >UniRef50_O45120 Cluster: Family 4 cytochrome P450; n=2; Coptotermes acinaciformis|Rep: Family 4 cytochrome P450 - Coptotermes acinaciformis Length = 501 Score = 253 bits (619), Expect = 1e-65 Identities = 116/230 (50%), Positives = 161/230 (70%), Gaps = 2/230 (0%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G K+R AFLDL+L++SQ G +++DEEI+E+VDT MFEGHDTT + SF + + +QD+Q Sbjct: 274 GLKRRHAFLDLMLQASQDGASLTDEEIREEVDTFMFEGHDTTTSALSFTMWCLAKYQDVQ 333 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 +K + EL QIFGDS R TF+D EMKYLE+ + ETLRLYP V RQ+ + T+ Sbjct: 334 EKAVVELKQIFGDSTRDATFRDLQEMKYLEQVIKETLRLYPSVNCFGRQLTENFTVGDYV 393 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 PAG + I Y LHRRP+ +P+P +FDPD FLPE RH Y +VPFSAGPR+C+G+ Sbjct: 394 N--PAGANVWIYPYHLHRRPEYFPDPERFDPDRFLPENCVGRHPYCYVPFSAGPRNCIGQ 451 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 K+A+L+LK +S +LR+F+VI + + + D +L+ A G +V+LQPR Sbjct: 452 KFAILELKSTISQVLRSFKVIESDCNGNIRYKLDFVLRSASGLKVKLQPR 501 Score = 136 bits (330), Expect = 1e-30 Identities = 79/234 (33%), Positives = 122/234 (52%), Gaps = 4/234 (1%) Query: 41 RRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVF 100 R +LADK+ N L+F G D +R +V+ Y H ++V++W G L+V Sbjct: 25 RSRMQLADKIPGPKALPVLGNLLDF-GLRPDRYRELVE-GLIYKHGTIVRLWSGAYLIVI 82 Query: 101 LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKS 160 L + + VE +LSS IDKA YRF PWLG+GLL STGQ + + +F L + Sbjct: 83 LTEAKYVEALLSSTSQIDKAYTYRFVWPWLGSGLLTSTGQALGNPPQAADSSFPLQGTRE 142 Query: 161 FIDLFNANSRAVVDKLKKEAS--NFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAM 218 F + +V+K + + FD YM+ C ++ + ET+MGV+ + Q S EY Sbjct: 143 FRGCVQQKWKILVEKFSRHVNGPEFDVTPYMTLCALDNMSETSMGVTLNAQKDSDSEYVR 202 Query: 219 AVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272 A+ + +I+ R K W D F+ + + Q K L I+H T+ VI+ +K+E Sbjct: 203 AIHSLGEIVFTRSGKPWYHSDTTFRLSTLGREQQKNLAILHSFTRSVIRSRKQE 256 >UniRef50_Q9VVN6 Cluster: Probable cytochrome P450 312a1; n=2; Sophophora|Rep: Probable cytochrome P450 312a1 - Drosophila melanogaster (Fruit fly) Length = 510 Score = 242 bits (592), Expect = 2e-62 Identities = 145/469 (30%), Positives = 249/469 (53%), Gaps = 38/469 (8%) Query: 74 RNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNG 133 R + ++ H+ K+W+G +L + +P+D++ + S+ + K +YR F+ WL G Sbjct: 59 RRATEMINEHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEG 118 Query: 134 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMS--E 191 L S +KW RK++ P F+ ++K F+ +F SR ++ + K A + D D++ Sbjct: 119 LFTSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLIS 178 Query: 192 C-TVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 250 C T++ + ETA+GVS +Q + EY AV + I+ R I+ R +FK T + K Sbjct: 179 CFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKR 238 Query: 251 QTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGL 310 + +L+ +HG T+ +I+ K+ +N+ A E ++ QSS Sbjct: 239 EQELIKTLHGFTEGIIQ---------KRIDEINQDA-------------ENRNY-QSSDA 275 Query: 311 KXXXXXXXXXGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFF 369 + G K+ L FLD LLL G ++ ++I+E+VDTI+F G D TA +FF Sbjct: 276 ELD-------GVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFF 328 Query: 370 LSMMGIHQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIAR 428 + M +H + Q + EE+ + G D P++ + ++++LE C+ ETLR+YP P+ AR Sbjct: 329 MYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTAR 388 Query: 429 QVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFV 488 + T+ N IP G+ ++I+ + R D +P+P F PD + F+ Sbjct: 389 KATANCTI--NDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFI 446 Query: 489 PFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIIL 537 PF AG RSC+G++YAM+ LK++L+ +LRNF + L E KL+ + ++ Sbjct: 447 PFMAGARSCMGQRYAMVMLKMVLAHLLRNF-LFEPLGERQVKLKLNFVI 494 >UniRef50_UPI00015B5014 Cluster: PREDICTED: similar to cytochrome P450 CYP4AB2; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis Length = 604 Score = 239 bits (586), Expect = 1e-61 Identities = 138/465 (29%), Positives = 238/465 (51%), Gaps = 21/465 (4%) Query: 88 VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 147 + K W L+ + P D+EVILSS K Y++ + WL +GLL + G +R+ R+ Sbjct: 148 ICKGWAMGLPLLSVRHPDDLEVILSSQKACYKEFPYKYLRSWLNDGLLTNKGDTYRARRR 207 Query: 148 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMGVS 205 ++ P FH N+L+ ++D+ N S ++ +L+ F D ++ ++ I++E+AMG+ Sbjct: 208 MLTPAFHFNMLRRYVDIMNEQSGRLMTELRANGKEFVLDVLPIYADVSLNIIIESAMGID 267 Query: 206 KSTQDQSGF-EYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264 D+ +Y A+ M +L R + ++ ++ FT+ + Q L ++ T K Sbjct: 268 LDKTDKKVIKDYKEAIEDMGIVLTYRMLRPYILDWMMTPFTEIGRKQIHALKVLREFTDK 327 Query: 265 VIK--RKKEEFASGKKP-SNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXG 321 +IK RK E G K ++ + S ++ + G Sbjct: 328 IIKERRKYHEMLGGIKGYKEFTDSLENQDESESIYVKIQLM------------IHHFFTG 375 Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 KK+L LD+LL + + G+ + ++ IKE+VDT + G DTT ++F +M ++ QD Sbjct: 376 HKKKLPMLDILLSAEKDGL-LDEKGIKEEVDTFLLGGTDTTRMVMAYFTMLMAENKKCQD 434 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 K E+ ++ S + +M YLE+C+ E++RLYP I R +I L + Sbjct: 435 KARAEVCKVLERSGGKRGMTELSQMPYLEQCIKESMRLYPIASTIFRHTVDDIQLKNY-- 492 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 IPAG ++ HR P+ + P KFDPD FLPE +RH +A++PFSAGPR+C+G+K Sbjct: 493 TIPAGVVVICQIIDAHRDPNFWTEPEKFDPDRFLPENCRHRHPFAYLPFSAGPRNCIGQK 552 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVR 546 + +++K + S +L NF + D +L D +L+ A+ F + Sbjct: 553 FGWMEVKAVCSRLLYNFYLEPIDSTRDMQLIGDFVLRPADPFHTK 597 >UniRef50_UPI0000D566B3 Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 511 Score = 237 bits (580), Expect = 6e-61 Identities = 107/233 (45%), Positives = 168/233 (72%), Gaps = 1/233 (0%) Query: 321 GQKKRLAFLDLLLESSQSGVA-ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 G+KKRLAFLDLLLE++++ ++DE+I+E+VDT MF GHDT+ + L + + + Sbjct: 279 GKKKRLAFLDLLLEANKNSEGGLTDEDIREEVDTFMFAGHDTSTVTVGWTLFTLSNYPEY 338 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q+KV +ELD+IF +RP+T QD L+M+YL++ + ET RL P VP+IAR ++Q++ + ++ Sbjct: 339 QEKVHQELDEIFQGEERPITPQDVLKMQYLDKVIKETQRLIPVVPVIARTLDQDLEIVAS 398 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 + IPAG +VI +LH+ PD +P P++FDP+ FLPE + RH Y+FVPFSAGPR+C+G Sbjct: 399 SRTIPAGVMVVIHLARLHKDPDQFPEPDRFDPERFLPENVSKRHPYSFVPFSAGPRNCLG 458 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552 +K+A+ KV+L++ILR ++V ++ K + K +I+L+ G V L+PR+R Sbjct: 459 QKFALRNTKVLLASILRKYKVRAEKKIDEMKYNIEIVLRPQGGLSVALEPRRR 511 Score = 144 bits (348), Expect = 7e-33 Identities = 77/248 (31%), Positives = 130/248 (52%), Gaps = 4/248 (1%) Query: 33 YAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIW 92 + W R+R+++ + + LE + F + V + + + + W Sbjct: 19 FCKWLKDRKRIWDAIEPIGGEKWYPLIGTCLELIKTKRKDFYD-VYCARNMKYGPFFRTW 77 Query: 93 IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLI-STGQKWRSHRKLIAP 151 +G V + P VE ILSS V + K + YRF PWLG GL+ S +KWR HRKLI P Sbjct: 78 MGFIPAVHVMKPDHVERILSSTVNLTKGDNYRFVVPWLGEGLITGSNHKKWRVHRKLITP 137 Query: 152 TFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAMGVSKSTQ 209 TFH ++L + +++ + + ++L +A+ F+ + +++ C ++I+ ETAMGV + Sbjct: 138 TFHFSILDNMMEVMAEKGQFLAEQLVPKANGQFFNIYPFLTLCELDIICETAMGVEVNAM 197 Query: 210 DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRK 269 S EY +V + DI+ R +L PD +F + + K L I+HG T+KVI+ + Sbjct: 198 KHSQSEYVRSVYGISDIMLYRMFHPYLHPDFVFNLSSKGRQHKKYLSILHGFTRKVIQER 257 Query: 270 KEEFASGK 277 KE+ SG+ Sbjct: 258 KEKLTSGR 265 >UniRef50_Q6ZWL3 Cluster: Cytochrome P450 4V2; n=83; Coelomata|Rep: Cytochrome P450 4V2 - Homo sapiens (Human) Length = 525 Score = 226 bits (553), Expect = 1e-57 Identities = 107/230 (46%), Positives = 157/230 (68%), Gaps = 3/230 (1%) Query: 322 QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 + KR AFLDLLL + G +S E+I+E+VDT MFEGHDTTAA ++ L ++G + ++Q Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 KV ELD +FG SDRP T +D +++YLE + ETLRL+P VP+ AR V+++ + G Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 ++ GT VI Y LHR P +PNP +F P+ F PE + RH YA+VPFSAGPR+C+G+ Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 K+A+++ K ILS ILR+F + S+ K + L+ +IL+ + G ++L+ R Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520 Score = 167 bits (405), Expect = 9e-40 Identities = 79/204 (38%), Positives = 120/204 (58%), Gaps = 2/204 (0%) Query: 71 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 130 + F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131 Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 188 G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V KL+K + F+C Y Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191 Query: 189 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYA 248 ++ C ++I+ ETAMG + Q EY AV +M +++ R WL DL + Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEG 251 Query: 249 KNQTKLLDIIHGLTKKVIKRKKEE 272 K L I+H T VI + E Sbjct: 252 WEHKKSLKILHTFTNSVIAERANE 275 >UniRef50_UPI0000E46807 Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily v; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily v - Strongylocentrotus purpuratus Length = 487 Score = 226 bits (552), Expect = 1e-57 Identities = 106/231 (45%), Positives = 159/231 (68%), Gaps = 2/231 (0%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G K+R+AFLDLLL+ + + + +I+E+VDT MFEGHDTTAA +S+ + ++G H +Q Sbjct: 218 GSKRRIAFLDLLLKMQRDDPSFTKSDIREEVDTFMFEGHDTTAALASWAMFLIGHHTRVQ 277 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 K+ +ELD +FGDSDRPVT D ++ YL L ETLR++P VPI+ R + ++ + +G Sbjct: 278 KKLHQELDSVFGDSDRPVTADDLQKLPYLTCVLKETLRIFPSVPIVGRDLQEDCII--DG 335 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 K P GT L+IA LHR P +P P FDPD FLPE S+ RH +++VPFSAGPR+C+G+ Sbjct: 336 KLAPRGTLLIIAIGSLHRDPTQFPEPLMFDPDRFLPEFSSKRHPFSYVPFSAGPRNCIGQ 395 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 ++A+++ KV+L+ +LR F + S D A++IL+ +EG +++ RK Sbjct: 396 RFALMEDKVLLANVLRCFSLESTQSLKDTMPIAELILRPSEGIHMKITRRK 446 Score = 100 bits (239), Expect = 1e-19 Identities = 60/168 (35%), Positives = 88/168 (52%), Gaps = 11/168 (6%) Query: 98 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNV 157 L F DP ++ +SS V EEYR L + + TG+KW RK++ PTFH + Sbjct: 48 LQFKQDPNELVEQVSSWV-----EEYRTKSKGL---MRLCTGKKWFHRRKMLTPTFHFAI 99 Query: 158 LKSFIDLFNANSRAVVDKLKKEASNFDCHDY---MSECTVEILLETAMGVSKSTQDQSGF 214 L +FI++F+ S + K + A D + ++ C ++I+ ETAMG QD+S Sbjct: 100 LHNFIEVFDEQSNTLCQKFGEHAQKQDLVNICPLVTLCVLDIISETAMGKQLHAQDESNN 159 Query: 215 EYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262 +Y AVM+M DI+ R K W PD LF T K + L I+H +T Sbjct: 160 DYVNAVMRMSDIIQQRQKKPWFWPDPLFDNTKSGKEHAQCLQILHKMT 207 >UniRef50_UPI00015B561A Cluster: PREDICTED: similar to cytochrome P450 CYP4AB2; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis Length = 478 Score = 225 bits (551), Expect = 2e-57 Identities = 134/451 (29%), Positives = 231/451 (51%), Gaps = 31/451 (6%) Query: 90 KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149 +IW +V DP D+ ++L+ I K Y +F GL+ STG+KW+ RK++ Sbjct: 39 RIWFFTCAVVITQDPDDLRILLTDKTNITKGFVYEYFHLMAKTGLITSTGEKWQYRRKIL 98 Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMGVSKS 207 P FH +++K ++ + V +K + S+ T+ I+LE AMG+ Sbjct: 99 TPAFHTHIIKKYMKITFEQGERFVKSIKAQGDETVQSLIPVCSDLTLSIILEAAMGIQFQ 158 Query: 208 TQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIK 267 T EY A+ + R T+ +++ D + ++ + + ++ T K+I Sbjct: 159 TIGNKAEEYRKAIEHYFSSIAYRATRPYIK-DWMLRYFSEGRRILATVKVLREFTDKIID 217 Query: 268 RKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLA 327 ++ E+ K + + + + T EG +KKRLA Sbjct: 218 ERR-EYHKQTKQESFQKYV--DDDMEHECTDGEG--------------------RKKRLA 254 Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 LDLLL + + G+ I +E IKE+VDT G+DTT + L +M ++D Q+ E Sbjct: 255 MLDLLLMAEKEGL-IDEEGIKEEVDTFTAAGYDTTGMEMVYLLMLMAENKDQQELARAEA 313 Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447 ++I S ++ ++ +M+Y+ERC+ E+LRL+P P I R V ++I L + +PAGT Sbjct: 314 NRILDASGGKISMKEINQMEYIERCVKESLRLFPTAPHIVRAVTEDIQLKNY--MVPAGT 371 Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507 + + + LHR P + +P KFDPD FLP + R+ + ++PFS GPR+C+G+K+A+ +L Sbjct: 372 DIFVPIHILHRDPKYWSDPLKFDPDRFLPGEAEKRYPFTYLPFSHGPRNCIGQKFAIAEL 431 Query: 508 KVILSTILRNFRV--ISDLKESDFKLQADII 536 K +L+ +LRNF + +S K+ F L ++ Sbjct: 432 KSLLACVLRNFYLEPVSYTKDLQFTLHVVLL 462 >UniRef50_A0JMQ6 Cluster: Cytochrome P450, family 4, subfamily V, polypeptide 2; n=9; Coelomata|Rep: Cytochrome P450, family 4, subfamily V, polypeptide 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 513 Score = 221 bits (541), Expect = 3e-56 Identities = 98/232 (42%), Positives = 161/232 (69%), Gaps = 3/232 (1%) Query: 321 GQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 G +KR AFLD+LL++ + G ++ ++I+E+VDT MFEGHDTTAA ++ + ++G H ++ Sbjct: 280 GMRKRRAFLDMLLKTKDEDGKMLTHKDIQEEVDTFMFEGHDTTAAAMNWAIHLLGSHPEV 339 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q K +EL ++FG+S+RPV +D +++YLE + E+LRL+P VP AR + + + N Sbjct: 340 QRKAQQELFEVFGESERPVNTEDLKKLRYLECVIKESLRLFPSVPFFARTICDDTQI--N 397 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G K+P GT +V+ TY LHR P +P+P +F P+ FLPE RH YA++PFSAG R+C+G Sbjct: 398 GFKVPKGTNIVVITYALHRDPRFFPDPEEFRPERFLPENCVGRHPYAYIPFSAGLRNCIG 457 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 +++A+++ KVIL+ ILR F +++ K + + +++L+ +G + L+ RK Sbjct: 458 QRFAIMEEKVILAYILRYFNIVACQKREELRPLGELVLRPEQGIWITLERRK 509 Score = 169 bits (412), Expect = 1e-40 Identities = 77/213 (36%), Positives = 123/213 (57%), Gaps = 3/213 (1%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120 NAL+F + D F +V + ++ + ++KIWIGP + L+ VE +L++ V+IDKA Sbjct: 55 NALQFKS-NGDFFLQLVGYTTEFQNSPLLKIWIGPIPFLILFHAETVETVLNNPVHIDKA 113 Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180 Y+F PWLG GLL STG KWR RK++ PTFH ++L F+++ N + +++KL+K+A Sbjct: 114 YAYQFLHPWLGTGLLTSTGDKWRRRRKMLTPTFHFSILTEFLEVMNEQAEVLIEKLEKQA 173 Query: 181 SN--FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRP 238 F+C +++ C ++I+ ETAMG Q EY V +M DI+ R W P Sbjct: 174 GKGPFNCFSHITLCALDIICETAMGKRIYAQSNYDSEYVRTVYRMSDIITRRQRMPWYWP 233 Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKE 271 D ++ + + + L I+H T+ VI + E Sbjct: 234 DFVYNYVGEGREHNRSLKILHSFTESVINERAE 266 >UniRef50_Q9NGQ5 Cluster: Insecticide resistance-associated cytochrome P450; n=2; Cucujiformia|Rep: Insecticide resistance-associated cytochrome P450 - Diabrotica virgifera virgifera (western corn rootworm) Length = 501 Score = 219 bits (535), Expect = 2e-55 Identities = 102/229 (44%), Positives = 149/229 (65%), Gaps = 2/229 (0%) Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 ++K+LAFLDLLL + S I D+ IK++V+T MFEGHDTTA G S+ L + H + QD Sbjct: 273 KRKKLAFLDLLLNAKLSKGIIDDQGIKDEVNTFMFEGHDTTATGISWILRQLATHSEYQD 332 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 ++ EE+ + GD+ + D E+K +ER + ETLRL+PPVP IAR ++++I L NG Sbjct: 333 QIYEEIITVLGDAQKQPDLNDLNELKVMERFIKETLRLFPPVPYIARTLDEDIEL--NGY 390 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 IP ++ I Y +HR P +P P KFDPD FLPE NRH +A+VPFSAGPR+C+G++ Sbjct: 391 LIPKEASIDIWIYDIHRNPKHWPEPEKFDPDRFLPENCVNRHPFAYVPFSAGPRNCIGQR 450 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +AM ++K I+ I++NF V K ++ D++L+ A + PR Sbjct: 451 FAMYEMKAIICGIMQNFSVKLADKNEKVEIMTDLVLRSAHEINLNFIPR 499 Score = 96.7 bits (230), Expect = 1e-18 Identities = 60/227 (26%), Positives = 106/227 (46%), Gaps = 9/227 (3%) Query: 65 FVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR 124 F S +F+N + S Y V + P +V + P + E I S +I K Y Sbjct: 52 FYSDSVQLFKNFREWSRKYSPLYSVVVLDIP--VVVVTGPDEFEKIASGSKHITKGMIYG 109 Query: 125 FFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE--ASN 182 +PWLG GLL ++G W+ RK++ P FH ++L+ F+ +FN + +V+ +K+E S Sbjct: 110 LVEPWLGKGLLTNSGSLWQQRRKILTPAFHFSILQEFVKVFNKETARLVETIKQENKKSA 169 Query: 183 FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLF 242 + +S+ + + ET+ G + + Y A+ +M IL R + W +F Sbjct: 170 TNIIPLISQTALNTIAETSFGTTLDLTKKDDKNYVSAIHEMGKILIYRMVRPWFYSLFVF 229 Query: 243 KFTDYAKNQTK-LLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATT 288 + K +L +H T+++I + ++F KP +N T Sbjct: 230 YILSSVGAKLKQVLSTLHSFTERIIPERSKDF----KPFEVNTDGET 272 >UniRef50_A1BPS2 Cluster: CYP4BF1; n=2; Ips paraconfusus|Rep: CYP4BF1 - Ips paraconfusus Length = 511 Score = 213 bits (520), Expect = 1e-53 Identities = 102/230 (44%), Positives = 153/230 (66%), Gaps = 3/230 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G K R AFLDLLL G ++DE+I+E+VDT MFEGHDTT++G S+ + + H D Q Sbjct: 281 GGKTRRAFLDLLLSIQDEG-KLTDEDIREEVDTFMFEGHDTTSSGMSWTIWCLAHHLDYQ 339 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 +KVI+E+D +FG+SDR T +D E+KYLE+C+ E +RLYPPVP+I+R+V ++ G Sbjct: 340 NKVIQEIDAVFGNSDRNCTNEDLKELKYLEQCIKEAMRLYPPVPLISRKVEEDFHCA--G 397 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +P T++I+ LHR P +Y N ++P+NF P A RH Y+F+PFSAGPR+C+G+ Sbjct: 398 YDVPRDATILISPLVLHRDPALYENVESYNPENFSPSAIARRHAYSFIPFSAGPRNCIGQ 457 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 K+A+++ + +LS R + V S + A IILK ++G +++ R Sbjct: 458 KFALMEERTVLSWFFRRYCVRSSEEFLSNIPCAKIILKPSKGVPIKIYRR 507 Score = 145 bits (352), Expect = 2e-33 Identities = 80/277 (28%), Positives = 141/277 (50%), Gaps = 12/277 (4%) Query: 21 FYVLLVPAVILWYAY-----WRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRN 75 F+V +V ++ YA W + R+RL ++ D++ A +F D Sbjct: 3 FWVPVVVLLLFVYATLRIWPWILKRKRLIQMVDRIPGPTAIPILGCAYQFRPKIEDFSYE 62 Query: 76 IVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLL 135 +++ + + VV+ W+GP +V + P V+ +L S+ I K +EY + WLG GLL Sbjct: 63 LLEYARLHKDSEVVRFWLGPIPIVCAFGPESVKTVLESNKVITKGDEYDILERWLGTGLL 122 Query: 136 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSEC 192 ISTG KWRS RK++ FH NVL F+D ++ +R +D++++ A FD ++ C Sbjct: 123 ISTGNKWRSRRKMLTMAFHFNVLNGFMDTYDKEARIFLDQIREFADTNEPFDVCPFIKRC 182 Query: 193 TVEILLETAMGVSKSTQDQSGFEY--AMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 250 ++I+ ET+M Q Y A+A M L+ R W++P +++F + +N Sbjct: 183 ALDIICETSMAHKIDAQVDHNHPYVNAVAQMNTLSFLYARSPWFWIKP--IWRFFGHEEN 240 Query: 251 QTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETAT 287 + L ++ T+ VI +++E + KK N++ T Sbjct: 241 YERNLKLVTDFTQNVIAERRKELHTAKKTVQENKSGT 277 >UniRef50_Q178T9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 511 Score = 210 bits (513), Expect = 7e-53 Identities = 142/475 (29%), Positives = 248/475 (52%), Gaps = 38/475 (8%) Query: 85 HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144 H+ + I IGP++ + L P V+ +L+ +K+ Y + L NGLL S + W+ Sbjct: 67 HDRMFAIHIGPKVAIGLSHPELVQQVLNHPYCQEKSNVYELLR--LPNGLLSSKYKVWKL 124 Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETA 201 HRK + TF+L +L SF+ +FN ++R ++ L + AS F+ ++ CT+ ++ ET+ Sbjct: 125 HRKTLNSTFNLRILNSFLPIFNDSTRKLIQLLDQYASTGKTFNILAPLTHCTLGMVCETS 184 Query: 202 MGVSKSTQDQSGFEYAMAVMK-MCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHG 260 G K ++ G E ++ + L R + L +++++ T +++TK + Sbjct: 185 FG--KKVLEREGKEQFFDDLEVLLTSLGKRVVNVLLHSEIIYRLTPMYRDETKSRAVCRQ 242 Query: 261 LTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXX 320 T KVI+ K+ E S + + T+E G L+ EG ++ Sbjct: 243 FTDKVIEEKRIEIESSFAGDS---SLITTE---GTLSDDEGEAY---------------- 280 Query: 321 GQKKRLAFLDLLLES---SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 377 K+ F+D LL+ ++S +D EI +QV T++ G++T+A + ++ ++ Sbjct: 281 --KRPQIFIDQLLKMPLMTKSAYNFTDLEISDQVFTMIIAGNETSATQMAHTCLLLAMNP 338 Query: 378 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 437 IQ K +E+ Q + + ++ Y+E L E++RL P +I+R+ Q+I L Sbjct: 339 AIQQKAYQEVQQFIETENSYIDADILRKLVYIEAVLKESMRLLPVGSLISRKNLQDIVL- 397 Query: 438 SNGKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496 +G IP T L++ Y LHRRPD++ + +F P+ FL E S RH YAF+PFS GPR Sbjct: 398 -DGHIIPKNTPLLMKPYSLHRRPDIWGSDAEQFVPERFLGEDSKRRHPYAFIPFSGGPRG 456 Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 C+G +YAM+ LK++L+ IL+NF + + LK D ++ + L A V L+ R+ Sbjct: 457 CIGLRYAMMTLKIMLALILKNFEISTQLKYRDLRIHYQLSLNLAGPHAVSLERRR 511 >UniRef50_Q695H3 Cluster: Pheromone-degrading enzyme; n=2; Phyllopertha diversa|Rep: Pheromone-degrading enzyme - Phyllopertha diversa (Pale-brown chafer beetle) Length = 502 Score = 210 bits (512), Expect = 1e-52 Identities = 100/231 (43%), Positives = 152/231 (65%), Gaps = 3/231 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G+KK+ AFLDLLLE S + + +++ I+E+VDT MFEGHDTTA +F L + ++ IQ Sbjct: 271 GRKKKQAFLDLLLEYSANDPSFTEQHIQEEVDTFMFEGHDTTATSITFALYALAMNPHIQ 330 Query: 381 DKVIEELDQIFGD-SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 +K EL +IF + S R +++D EMKYLE + ETLR+Y VP +R + +++ + N Sbjct: 331 EKAYAELKEIFSNNSKRHASYRDLQEMKYLEMVIKETLRIYTTVPFYSRALEEDVNM--N 388 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G+ +P GT L + Y +H P +Y +P FDP+ F E S R +AF+PFSAGPR+C+G Sbjct: 389 GQILPKGTMLNVFAYGVHHNPKIYKDPETFDPERFSIENSKERSPFAFIPFSAGPRNCIG 448 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +K+AML++K +S +LRNF+++ + L+++ +LK G VRLQ R Sbjct: 449 QKFAMLEMKSSISDVLRNFKLLPSVPAHKVVLKSEAVLKSDNGVFVRLQKR 499 Score = 167 bits (406), Expect = 7e-40 Identities = 89/261 (34%), Positives = 142/261 (54%), Gaps = 5/261 (1%) Query: 25 LVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYD 84 L+ ++ILW YW + YE K + +G ++++ S Y Sbjct: 9 LLCSLILWLVYWYYKINK-YEKYLKTVPGPARTPIMGNIPDIGSPVSFLEDLLKLS--YM 65 Query: 85 HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144 ++ K++IG + VFL +P+D+E +L+S + K++ Y+F WLG GLL S+G KW+ Sbjct: 66 YKGNFKLYIGAQPRVFLVEPKDLEFLLNSTSLLTKSKSYKFLYRWLGAGLLTSSGNKWKK 125 Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK--KEASNFDCHDYMSECTVEILLETAM 202 HRK+I P FH +L+ FID+FN+ S +V+KL S+ D + +++ CT++I+ ETAM Sbjct: 126 HRKIITPAFHFQILEEFIDVFNSASDVLVEKLNAAPNKSSIDIYPFIARCTLDIICETAM 185 Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262 G S Q+ EY +V + IL R L DLL+ FT + + L ++HG T Sbjct: 186 GTSVDAQNDINSEYVNSVKILLGILVQRSLSPILANDLLYPFTTTYQKEKAALKVVHGYT 245 Query: 263 KKVIKRKKEEFASGKKPSNLN 283 K VI ++K EF + K + N Sbjct: 246 KSVINKRKIEFYNNSKSEDRN 266 >UniRef50_UPI0000D55ACE Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 501 Score = 209 bits (510), Expect = 2e-52 Identities = 99/231 (42%), Positives = 146/231 (63%), Gaps = 5/231 (2%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G+KK+ FLDL+L ++ G ++S EEI+E+VDT MF GHDTT +SF L + +++ Q Sbjct: 275 GRKKKKVFLDLILSATTDGQSLSPEEIREEVDTFMFGGHDTTGTATSFILYCIANNKEAQ 334 Query: 381 DKVIEELDQIFGDSDRP-VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 +K++EE Q+FGD P VT+ EMKYLE + E LRLY PVPI R ++Q+ N Sbjct: 335 EKILEEQKQLFGDERSPKVTYSTLQEMKYLENAIKEGLRLYSPVPIYGRLIDQDTEY--N 392 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G IP G ++I + +H P YPNP KFDP F E + + + F+PFSAGPR+C+G Sbjct: 393 GTMIPKGVGVIIFAHGIHMNPKYYPNPEKFDPSRF--ENTTGKDPFTFIPFSAGPRNCIG 450 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +KYAML++K ++S ++RNF + + L + +LK G ++ L+ R Sbjct: 451 QKYAMLEIKSLVSKVVRNFELFPASPTHEMHLAPETVLKSLNGVKIGLKMR 501 Score = 136 bits (329), Expect = 1e-30 Identities = 78/261 (29%), Positives = 138/261 (52%), Gaps = 7/261 (2%) Query: 16 SAINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRN 75 S + F++ LV ++L + ++ RR+ A EF S+ + N Sbjct: 2 SVLTEFFIALVALILLPFYFYYTKIRRIENFFKHFPSPAGVPILGVAPEFKTTSS-VLDN 60 Query: 76 IVQKSADYDHESVVKIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGL 134 K A H ++V + GP + + D + +E +LSS+ + K+ RF +PW+G GL Sbjct: 61 F-HKYAKA-HGTMVHLKFGPFKHALLCTDTKFLEFLLSSNKLLKKSVNLRFLEPWIGTGL 118 Query: 135 LISTG-QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDC--HDYMSE 191 + + G KW++HRKLI P FH +L+ F+D+F + +V KL + + + C + Y+++ Sbjct: 119 VTADGGPKWKTHRKLITPAFHFKILEQFVDIFESGGDILVKKLSEVSGSKSCDIYPYITK 178 Query: 192 CTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQ 251 CT++I+ ETAMG Q+ Y ++ +MC I +R +L D +F+F+ K Q Sbjct: 179 CTLDIICETAMGTKVDVQNTENSAYFESIKEMCRIFTVRTVGAFLSNDFIFRFSKDYKIQ 238 Query: 252 TKLLDIIHGLTKKVIKRKKEE 272 TK + ++H + +VI K++E Sbjct: 239 TKAVKVLHNHSNEVIVNKRKE 259 >UniRef50_Q170T4 Cluster: Cytochrome P450; n=5; Endopterygota|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 497 Score = 209 bits (510), Expect = 2e-52 Identities = 100/232 (43%), Positives = 154/232 (66%), Gaps = 6/232 (2%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G KK++AFLD+LL++S G ++D+EI+E+VDT MFEGHDTT +F L ++ H ++Q Sbjct: 269 GSKKKMAFLDVLLQASVDGKPLTDKEIQEEVDTFMFEGHDTTTIAIAFTLLLLARHPEVQ 328 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 +KV +E+ +I G D P T+++ +MKYLE + E+LRLYPPVPII R+ ++ T+ Sbjct: 329 EKVYKEVTEIIGTDLSIPATYRNLQDMKYLEMVIKESLRLYPPVPIIGRKFTEKTTI--G 386 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHY-YAFVPFSAGPRSCV 498 G IP + + +HR P ++ +P KFDP+ F PER+ + YA++PFSAGPR+C+ Sbjct: 387 GNVIPEDSNFNLGIIVMHRDPKLFDDPEKFDPERFSPERTMEQSSPYAYIPFSAGPRNCI 446 Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 G+K+AML+LK LS ++RN+R+ E +Q + LK +G ++ PR Sbjct: 447 GQKFAMLELKSTLSKVIRNYRLTEAGPEPQLIIQ--LTLKPKDGLKIAFVPR 496 Score = 160 bits (388), Expect = 1e-37 Identities = 72/188 (38%), Positives = 116/188 (61%), Gaps = 2/188 (1%) Query: 87 SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146 ++ ++W+G RL +F + D E +LSS I K+E Y+F PWLGNGLL+ST QKW + R Sbjct: 66 TMFRVWVGTRLALFCTNTPDTETVLSSQKLIRKSELYKFLVPWLGNGLLLSTDQKWFNKR 125 Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAMGV 204 K+I P FH +L+ FI++F+ S +V KLK EAS + + Y++ C ++++ ETAMG Sbjct: 126 KIITPAFHFKILEQFIEVFDRQSGILVQKLKPEASGKLVNVYPYVTLCALDVICETAMGT 185 Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264 + Q +Y AV ++ +L R K+W R D LF + K Q K++ ++H T Sbjct: 186 PINAQTDVDSKYVRAVTELSYLLTTRFVKVWQRSDFLFNLSPDRKRQDKVIKVLHDFTTN 245 Query: 265 VIKRKKEE 272 +I+++++E Sbjct: 246 IIQKRRKE 253 >UniRef50_Q8ISJ8 Cluster: Cytochrome P450 CYP4S4; n=3; Noctuidae|Rep: Cytochrome P450 CYP4S4 - Mamestra brassicae (Cabbage armyworm) Length = 492 Score = 208 bits (509), Expect = 2e-52 Identities = 106/222 (47%), Positives = 146/222 (65%), Gaps = 6/222 (2%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G KKR A LDLLLE+ G I E I+E+V+T+MFEGHDTTA L ++ H+++Q Sbjct: 268 GGKKRYAMLDLLLEAENKG-EIDLEGIREEVNTLMFEGHDTTAMAIVLGLMLIADHEEVQ 326 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 D++ EE +I GDSDR T D +MKYLE + ETLRLYP VP IAR++ ++ L + Sbjct: 327 DRIFEECQKILGDSDRTPTMSDLADMKYLEAVIKETLRLYPSVPFIAREITEDFML--DD 384 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 + G+ + I Y LHRRPD++P P+ F PD FL A H YAFVPFSAGPR+C+G+ Sbjct: 385 LPVKKGSEVSIHIYDLHRRPDLFPEPDAFIPDRFL--SGAPMHPYAFVPFSAGPRNCIGQ 442 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEG 542 ++AML++K + S I RNFR+ ++ L AD+++ R EG Sbjct: 443 RFAMLEMKCVFSAICRNFRLAPKVQGYRPALLADMLI-RPEG 483 Score = 128 bits (309), Expect = 4e-28 Identities = 73/219 (33%), Positives = 119/219 (54%), Gaps = 5/219 (2%) Query: 62 ALEFVGGSA-DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120 ALEF+ S ++F + Q +Y V+K+ R ++ L + +DVEV+LS I K+ Sbjct: 41 ALEFLKISPRELFLKMRQYKKEYGDRYVIKMM--KRRILHLSNEKDVEVVLSHSRNIKKS 98 Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-E 179 + Y F + WLG GLL+S+G KW RK++ PTFH N+LKSF + SR++V+ L E Sbjct: 99 KPYTFLEAWLGTGLLLSSGAKWHRRRKILTPTFHFNILKSFTVVMKEKSRSLVETLNNLE 158 Query: 180 ASNFDCHDYMSECTVEILLETAMGVSKSTQDQS-GFEYAMAVMKMCDILHLRHTKIWLRP 238 + + +S+ T+ + ETAMG S EY A++++ ++L R T++WL Sbjct: 159 GTEVNLLPVISDYTLYTICETAMGTQLDADKSSKTLEYKTAILEIGNLLLGRLTRVWLHN 218 Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGK 277 + LFK + L+ +H VI +K+ + G+ Sbjct: 219 EYLFKKFPIGRRFENCLEKVHSFADDVIMERKKNWKPGQ 257 >UniRef50_O17851 Cluster: Putative uncharacterized protein cyp-37B1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein cyp-37B1 - Caenorhabditis elegans Length = 509 Score = 208 bits (508), Expect = 3e-52 Identities = 96/228 (42%), Positives = 151/228 (66%), Gaps = 3/228 (1%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 K+ +AFLDLLLE G+ +++++I+E+VDT MFEGHDTT+A + L + + + Q+K Sbjct: 281 KRSMAFLDLLLELRNEGL-MNEDDIREEVDTFMFEGHDTTSASMGWTLWCLAHNPEFQEK 339 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 VI+E+D IFG SDR T D +MKYLE+CL E+LR+YP VP R V Q++ + NG Sbjct: 340 VIQEVDGIFGTSDRDCTNDDLKQMKYLEKCLKESLRMYPSVPFFGRTVEQDVVI--NGDF 397 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 P G +++ L R P ++ NPN+++P+NF ++ +RH Y+ +PFSAGPR+C+G+K+ Sbjct: 398 FPKGVRIIVMPLLLQRNPLIFDNPNQYNPENFSEDKIGSRHAYSDIPFSAGPRNCIGQKF 457 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 AM++ K ++S R +RV + K+ ++ILK + GF + + R Sbjct: 458 AMMEEKAVISWFFRKYRVTASQPFGMNKILPELILKSSLGFPLTVHHR 505 Score = 122 bits (294), Expect = 3e-26 Identities = 62/188 (32%), Positives = 100/188 (53%), Gaps = 3/188 (1%) Query: 89 VKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148 + +W+GP L+ + +P+ + IL S+ I KAEEY PWLG GLL STG KWR RK+ Sbjct: 81 IGLWLGPVPLIAVINPQHAKEILESNEVITKAEEYDILFPWLGTGLLTSTGSKWRQRRKM 140 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 205 + P FH VL F+ + + ++ ++++K A + D Y+ ++++ +T+MGV+ Sbjct: 141 LTPAFHFKVLNDFLSVHDYQAKVFLEQIKPYADSGKEVDLFPYIKRLALDVICDTSMGVT 200 Query: 206 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKV 265 Q+ +Y +V + + + WLR L+ T + L I+ TK V Sbjct: 201 IDAQNNHDHQYVESVRLLSEYAFEWILRPWLRLKPLWYLTGPGHEYDRHLKIVTDFTKTV 260 Query: 266 IKRKKEEF 273 IK K EEF Sbjct: 261 IKEKWEEF 268 >UniRef50_UPI0000D55B03 Cluster: PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1) - Tribolium castaneum Length = 492 Score = 206 bits (503), Expect = 1e-51 Identities = 102/229 (44%), Positives = 152/229 (66%), Gaps = 4/229 (1%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 FLD L+E + +DEE+ + +++ G D TA S+ L M+ + QDIQDKV EEL Sbjct: 262 FLDYLVELTDREGRWTDEELTNETRSVIMAGSDATALTLSYCLVMLAMFQDIQDKVYEEL 321 Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447 +FGDSDR VT D ++YL+R + ETLR++P +I R++ ++T+ +G IP GT Sbjct: 322 CSVFGDSDRFVTVDDLPHLQYLDRFIKETLRVFPVTSMIGRELTTDMTI--DGHFIPKGT 379 Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507 ++ +HR P+ YP+P KFDPD FLPE A RH F+PFS GPR+C+G +YAM+ + Sbjct: 380 SIGFPILYIHRNPEYYPDPLKFDPDRFLPEEVAKRHPCTFIPFSFGPRNCIGYRYAMMTM 439 Query: 508 KVILSTILRNFRVI-SDLKE-SDFKLQADIILKRAEGFQVRLQPRKRMA 554 KVIL+T+LR+F+++ + KE S+ K++ DI K EG+ VR++ RK +A Sbjct: 440 KVILATLLRSFKMVHTPYKEISELKIKFDIATKVDEGYPVRMELRKNVA 488 Score = 121 bits (292), Expect = 4e-26 Identities = 69/251 (27%), Positives = 130/251 (51%), Gaps = 10/251 (3%) Query: 25 LVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYD 84 L+ VI + W + + A K+ +A GG+ +I N V+ + Y Sbjct: 8 LIFTVIALWLLWSFLWKNFF--ATKIKGPWAFPLIGSAYVLFGGTHNILENTVRVVSKY- 64 Query: 85 HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144 + K+W+G +L +F +P D+++IL+ ++K E YR+ K G+GL S +W+ Sbjct: 65 -RPLCKLWLGNKLTIFPSNPDDIQMILNRS--LEKEEGYRYIKTVFGHGLFTSPVSEWKG 121 Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETA 201 HRK+I T + VL SF+D +N +R +++KLK K+ + D M++CT++I+ + Sbjct: 122 HRKVIVSTLNQQVLNSFMDTYNIYTRELIEKLKIDTKDGQHIDMFPIMTQCTLDIICSSI 181 Query: 202 MGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261 MG + + ++ M + ++ ++ +R I+L P+L +K + +K +L I+ Sbjct: 182 MGTQMNAMKEES-QFIMWMTRVAELAIIRMFNIYLWPELFWKLSPISKESHELDQKIYNY 240 Query: 262 TKKVIKRKKEE 272 K VI K+ + Sbjct: 241 VKTVIHNKRHK 251 >UniRef50_UPI0000D55952 Cluster: PREDICTED: similar to Cytochrome P450 4d2 (CYPIVD2); n=2; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4d2 (CYPIVD2) - Tribolium castaneum Length = 501 Score = 205 bits (500), Expect = 3e-51 Identities = 99/231 (42%), Positives = 147/231 (63%), Gaps = 4/231 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G K+R A LD+LLE S +G ++DE+I+E+VDT MFEGHDTT F L + + D+Q Sbjct: 273 GIKRRAALLDMLLEVSDNGKNLTDEDIREEVDTFMFEGHDTTTTSICFVLYAIAQNPDVQ 332 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 K+ +EL + G D + +TF D E+KYL+ + E RLYPPVP+I R + ++ T+ + Sbjct: 333 KKIYDELVSVLGPDCKKEITFSDIQELKYLDVVIKEAHRLYPPVPLIERSLEEDCTI--D 390 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G IP T + I Y ++ DVYP P+ FDPD FLPE+ RH +A+VPFSAGPR+C+G Sbjct: 391 GLTIPKNTNISIFLYGMNYNKDVYPEPHVFDPDRFLPEKQGERHTFAYVPFSAGPRNCIG 450 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +K+A+L+LK ++ +LR F + D K ++ +LK G + L+ + Sbjct: 451 QKFALLELKTTIAKLLRCFEISPDPKNPP-QVGMCSVLKSRNGIHMFLKKK 500 Score = 165 bits (402), Expect = 2e-39 Identities = 80/192 (41%), Positives = 119/192 (61%), Gaps = 5/192 (2%) Query: 87 SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146 +VVK+W+GPRL + + P VE L+S V+++K++ Y FKPWLG+GLL+STG KW++ R Sbjct: 69 TVVKVWLGPRLHLLITKPEMVEFFLNSTVHLNKSDGYDLFKPWLGDGLLVSTGSKWKTRR 128 Query: 147 KLIAPTFHLNVLKSFIDL-FNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETA 201 KLI PTFH +L++F++ FN ++D L KEAS D H ++ C+++I+ ETA Sbjct: 129 KLITPTFHFKILENFLETSFNKQINILLDVLLKEASQTDKSIEIHSLINLCSLDIICETA 188 Query: 202 MGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261 G + Q + +Y AV +I LR WLR L+F+ +D + L I+H Sbjct: 189 FGTELNAQAKCNPKYVEAVTGFLEIFTLRFFSAWLRHPLIFRLSDKYAKYMEYLKILHDF 248 Query: 262 TKKVIKRKKEEF 273 T +IKR+KEEF Sbjct: 249 TNTIIKRRKEEF 260 >UniRef50_Q27472 Cluster: Cytochrome p450 family protein 32A1; n=3; Bilateria|Rep: Cytochrome p450 family protein 32A1 - Caenorhabditis elegans Length = 529 Score = 204 bits (497), Expect = 6e-51 Identities = 95/234 (40%), Positives = 160/234 (68%), Gaps = 4/234 (1%) Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 +KKR AFLDLLL + +SDE+I+E+VDT MFEGHDTT++G F + +G + + Q Sbjct: 289 EKKRKAFLDLLLTIQKEEGTLSDEDIREEVDTFMFEGHDTTSSGIGFTILWLGFYPECQK 348 Query: 382 KVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS-N 439 K+ +ELD++FG ++++P + D + YLE+C+ E+LR++P VP+IAR++++++T+ + Sbjct: 349 KLQKELDEVFGFETNQPPSMDDIKKCSYLEKCIKESLRMFPSVPLIARRLSEDVTINHPS 408 Query: 440 GKKI--PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 497 G+KI PAG ++ R P +P+P+ ++PDNF + A R YA++PFSAGPR+C Sbjct: 409 GQKIVLPAGLAACVSPIAAARDPRAWPDPDTYNPDNFDIDAIAGRDPYAYIPFSAGPRNC 468 Query: 498 VGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 +G+K+A+L+ K ILST R + V S E + + ++IL+ G +++++ R+ Sbjct: 469 IGQKFALLEQKTILSTFFRKYEVESLQTEENLRPVPELILRPYNGMKIKIKRRE 522 Score = 118 bits (283), Expect = 5e-25 Identities = 58/190 (30%), Positives = 102/190 (53%), Gaps = 6/190 (3%) Query: 86 ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 145 + ++ +WIGP +VFL + +L S+ I K +Y W+G GLL ST +KW Sbjct: 91 DGIMLLWIGPVPIVFLGTSECIRPVLESNTNISKPSQYDKMSEWIGTGLLTSTHEKWFHR 150 Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVD--KLKKEASNFDCHDYMSECTVEILLETAMG 203 RK++ PTFH +++ + +F N+ + D +L + FD Y CT++I+ ETAMG Sbjct: 151 RKMLTPTFHFTIIQDYFPVFVRNAEVLADAVELHVDGDYFDAFPYFKRCTLDIICETAMG 210 Query: 204 VSKSTQDQSGFEYAMAVMKMCDIL--HLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261 + + Q EY AV ++ +I+ H++ +WL+P ++ T + + + + Sbjct: 211 IQVNAQLGHNNEYVHAVKRISEIVWNHMKFPWLWLKP--IWYLTGLGFEFDRNVRMTNNF 268 Query: 262 TKKVIKRKKE 271 +KVI+ +KE Sbjct: 269 VRKVIQERKE 278 >UniRef50_Q9U1R5 Cluster: Putative uncharacterized protein cyp-42A1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein cyp-42A1 - Caenorhabditis elegans Length = 511 Score = 203 bits (496), Expect = 8e-51 Identities = 93/229 (40%), Positives = 159/229 (69%), Gaps = 5/229 (2%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 ++R+AFLDL+L+ + G + E I E+VDT FEGHDTT+A ++FL +MG + +IQ K Sbjct: 280 RRRMAFLDLMLDMNSKG-ELPMEGICEEVDTFTFEGHDTTSAAMNWFLHLMGANPEIQSK 338 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 V +E+D++ G++DRPV+++D ++KYLE C ETLRLYP VP+IARQ ++I + G Sbjct: 339 VQKEIDEVLGEADRPVSYEDLGKLKYLEACFKETLRLYPSVPLIARQCVEDIQV--RGHT 396 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 +P+GT +V+ +H+ P + +P F+P+ F+ +H YA++PFSAG R+C+G ++ Sbjct: 397 LPSGTAVVMVPSMVHKDPRYWDDPEIFNPERFI--TGELKHPYAYIPFSAGSRNCIGMRF 454 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 AM++ K IL+ IL+N +V + L+ + ++ A++I++ G +++ + R+ Sbjct: 455 AMMEEKCILAIILKNLKVKAKLRTDEMRVAAELIIRPLYGNELKFEKRE 503 Score = 127 bits (307), Expect = 7e-28 Identities = 68/206 (33%), Positives = 108/206 (52%), Gaps = 5/206 (2%) Query: 86 ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 145 E + ++W+G V LY +VE IL S ++K Y F W+G+GLLIS KWR Sbjct: 72 ERITRVWLGGLPFVLLYGAHEVEAILGSPKMLNKPFLYGFLSAWIGDGLLISKPDKWRPR 131 Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDY---MSECTVEILLETAM 202 RKL+ PTFH ++LK F++++N + R ++ K + +A + D ++ CT++++ E A+ Sbjct: 132 RKLLTPTFHYDILKDFVEVYNRHGRTLLSKFEAQAGTGEYSDVFHTITLCTLDVICEAAL 191 Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262 G S + Q Y AV KM DI+ R + D +F K + + I+H T Sbjct: 192 GTSINAQKDPHSPYLDAVFKMKDIVFQRLLRPHYFSDTIFNLIGPGKEHDECVKILHEFT 251 Query: 263 KKVI--KRKKEEFASGKKPSNLNETA 286 K I ++ K + A G + ETA Sbjct: 252 SKAIYARKAKVDAAGGVEQLLAQETA 277 >UniRef50_UPI0000D56462 Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily v, polypeptide 2; n=2; Tribolium castaneum|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily v, polypeptide 2 - Tribolium castaneum Length = 814 Score = 202 bits (493), Expect = 2e-50 Identities = 127/407 (31%), Positives = 214/407 (52%), Gaps = 33/407 (8%) Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLE 199 W+ HR++I PT + ++L +F + +++ L+K+ D + +++ V+++ E Sbjct: 433 WKKHRRIIVPTLNQSILNTFPQIICQQCDILLEILEKKCDKGEIDHYKFVTNFAVDVVSE 492 Query: 200 TAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 259 T GV + Q Y+ K+ +++ +R ++ D LF +T K + + + ++ Sbjct: 493 TIFGVPLNAQITDA-NYSRTFDKIMEVVFMRIFRVDYHSDFLFSWTKEYKAEQENVKLVK 551 Query: 260 GLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXX 319 T+ +I+R KK E T +L VEGL Sbjct: 552 ETTRDLIER--------KK-----------EQITCQL-EVEGLC----DWFISDSSRILV 587 Query: 320 XGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 +KKR FLD+L+ +S +E++++V T + G DT A F L+++G+HQD+ Sbjct: 588 VEEKKR-PFLDVLV-GKYLNEELSYQELEDEVSTFLLAGSDTNATAGCFVLTLLGMHQDV 645 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q+K+ EE+ ++ G P T D ++KY ER + ETLRL+P P IAR + +I L Sbjct: 646 QEKLYEEIIEVLGPEKYP-TLDDLPKLKYTERVIKETLRLFPGAPFIARIASDDIDL--G 702 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 IP G+ + + LHR + P KF+P+ FLPE A RH Y ++PFS G R+CVG Sbjct: 703 DYVIPRGSNIAVGYVHLHRSEKYWEEPLKFNPERFLPENVAKRHPYTWLPFSGGLRNCVG 762 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKE-SDFKLQADIILKRAEGFQV 545 K+ M+ +K+++S I+R FRV S +K D +L A+I+LK GF++ Sbjct: 763 GKFGMMVMKIMISMIIRKFRVKSSVKSVGDIELTANIVLKPKNGFRL 809 >UniRef50_UPI0000D56049 Cluster: PREDICTED: similar to Probable cytochrome P450 4d14 (CYPIVD14); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Probable cytochrome P450 4d14 (CYPIVD14) - Tribolium castaneum Length = 487 Score = 201 bits (490), Expect = 4e-50 Identities = 103/243 (42%), Positives = 150/243 (61%), Gaps = 8/243 (3%) Query: 309 GLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSF 368 G K G+KK AFLDLLL+ S +SD +I+E+VDT MF GHDTTA G F Sbjct: 247 GRKTNRNETEKSGKKK--AFLDLLLKFSDIE-KLSDRDIREEVDTFMFAGHDTTATGVCF 303 Query: 369 FLSMMGIHQDIQDKVIEELDQIFGDSDRP-VTFQDTLEMKYLERCLMETLRLYPPVPIIA 427 L ++ + ++Q+KV+ E ++FGD P VT+Q+ MKYLE + ETLRLYP VP+I Sbjct: 304 ALYLLANNPEVQEKVLSEQKELFGDEKNPCVTYQELQNMKYLEYVIKETLRLYPSVPVIG 363 Query: 428 RQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAF 487 R + ++ T + I A T + I Y +HR PD +P P KF P+ F E N YA+ Sbjct: 364 RYLKEDTTF--GDRVISAKTNVAIFIYGIHRNPDYFPEPEKFIPERF--ENMTNLPPYAY 419 Query: 488 VPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRL 547 +PFSAGPR+C+G+K+AML++K ++S ++R+F + + L A+ +LK A G ++ L Sbjct: 420 IPFSAGPRNCIGQKFAMLEMKSLISKVIRHFELTPANPHHELVLAAETVLKSANGIKIGL 479 Query: 548 QPR 550 + R Sbjct: 480 RAR 482 Score = 120 bits (290), Expect = 8e-26 Identities = 65/203 (32%), Positives = 109/203 (53%), Gaps = 7/203 (3%) Query: 88 VVKIWIGPRLLVFLY-DPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146 +VK+ +GP + D + VE LSS+ + K++ Y F + WLGNGL+++ G W+ HR Sbjct: 64 IVKLRLGPFFKALVVTDYKLVEFFLSSNSLLTKSQNYAFARSWLGNGLILANGTHWKQHR 123 Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEILLETAMGV 204 K++ P FHL +L+ +++ F++ R ++KLK + D + CT++++ ETAMG Sbjct: 124 KILTPAFHLEILREYLETFDSVGRIFIEKLKSLDNVQSVDLDALVPLCTLDVICETAMGT 183 Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264 + Q EY +V +MC I+ R + T + K+++I+H T K Sbjct: 184 KINAQKGENSEYVSSVKEMCRIIVARFLSPLKILKCTYWMTHDFYTERKVVNILHSFTSK 243 Query: 265 VIKRKK----EEFASGKKPSNLN 283 VI +K E SGKK + L+ Sbjct: 244 VIDGRKTNRNETEKSGKKKAFLD 266 >UniRef50_Q7YXL0 Cluster: Cytochrome P450 monooxygenase; n=2; Tribolium castaneum|Rep: Cytochrome P450 monooxygenase - Tribolium castaneum (Red flour beetle) Length = 491 Score = 200 bits (489), Expect = 6e-50 Identities = 91/229 (39%), Positives = 146/229 (63%), Gaps = 3/229 (1%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 +KRLA LDLLL+ G I DE I+E+VDT MFEGHDTT+ + L ++ H+++Q++ Sbjct: 264 RKRLAMLDLLLKYKSEGANIDDEGIREEVDTFMFEGHDTTSVSICYTLMLLANHREVQEE 323 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 +++E++ + + P T+ E+K+++R + E+LRLYP VP I+R EI + G Sbjct: 324 ILKEMEAVL--DEEPPTYAKLQELKFMDRVIKESLRLYPSVPFISRVSGSEIQTKT-GYT 380 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 IP + + Y +H P+V+P+P KFDPD FLPE RH +A++PFSAG R+C+G+K+ Sbjct: 381 IPKDCMVNLQIYDMHHNPNVFPDPEKFDPDRFLPENIQKRHPFAYIPFSAGSRNCIGQKF 440 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 AML++K +L IL+ F + + D +D++L+ +V+ PR+ Sbjct: 441 AMLEIKTVLCGILKKFILEAVDTRKDMAFVSDLVLRPKGSIKVKFVPRR 489 Score = 118 bits (284), Expect = 4e-25 Identities = 59/184 (32%), Positives = 99/184 (53%), Gaps = 2/184 (1%) Query: 99 VFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVL 158 V L +P DVE++L+ K+ Y F WLG GLL S G KW++ RK++ P FH N+L Sbjct: 80 VNLLNPEDVELVLTDTKQNTKSFIYHFLHSWLGTGLLTSRGPKWQNRRKILTPAFHFNIL 139 Query: 159 KSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEY 216 + FI +FN ++ +V+ L+ E+ D +++ T+ + ETAMG+ + D Y Sbjct: 140 QEFIQIFNEETKRLVEDLEAESHKPYIDVVVPITQFTLLSIGETAMGIKLNASDNDKDGY 199 Query: 217 AMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASG 276 AV K+ +L R + W+ + ++ T + + K+L +H + VI +K+ F+S Sbjct: 200 KRAVYKIGQLLTYRAPRPWIHNETIYSLTPQGRKEQKVLKSLHSFSNNVIAERKKHFSSS 259 Query: 277 KKPS 280 S Sbjct: 260 SYSS 263 >UniRef50_UPI00015B569E Cluster: PREDICTED: similar to cytochrome P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 512 Score = 198 bits (483), Expect = 3e-49 Identities = 94/219 (42%), Positives = 148/219 (67%), Gaps = 3/219 (1%) Query: 321 GQKKRLAFLDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 G++KR AFLDLLL +S++ ++ EE++E+VDT MF GHDTT++ S+ L + +I Sbjct: 281 GKRKRKAFLDLLLSASENASNPLTFEELREEVDTFMFAGHDTTSSAISWGLFALANAPEI 340 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q KV +EL +IFGDS + E+KYL+R + E LRLYP P+++R++ + + ++ Sbjct: 341 QAKVHKELQEIFGDSGETANSKQLSELKYLDRVIKEVLRLYPSAPMVSRRLTHDTVIDNH 400 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 +P GT + I Y++H P V+ +P FDPD FLPE +RH Y++VPFSAGPR+C+G Sbjct: 401 --HVPKGTFVNIHIYQMHHDPKVWKDPETFDPDRFLPENIRSRHPYSYVPFSAGPRNCIG 458 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILK 538 +K+A+L++K L+ ILR +++ S LK ++ K+ IL+ Sbjct: 459 QKFALLEVKTALTAILRKWQISSVLKPTEIKMIHTFILR 497 Score = 116 bits (278), Expect = 2e-24 Identities = 64/190 (33%), Positives = 102/190 (53%), Gaps = 5/190 (2%) Query: 88 VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 147 +V W+G + +V L P+ +EVIL S+ I KA Y + KPWLG+GL+ STG+ W SHR+ Sbjct: 73 MVLAWVGTQPIVILRRPQQMEVILPSNTLITKAATYDYMKPWLGDGLVTSTGELWFSHRR 132 Query: 148 LIAPTFHLNVLKSFIDLFNAN----SRAVVDKLKKE-ASNFDCHDYMSECTVEILLETAM 202 LI P FH VL+ + + + +LK + + + + + T++ + ETAM Sbjct: 133 LITPAFHFGVLEEYGAVMREKVEIFKECIESELKTDPKAPINIFGLVVKYTLDTICETAM 192 Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262 GV+ TQ Y AV + R K WL+ + ++ T+ K + I+H T Sbjct: 193 GVNIDTQRNPESAYVKAVHTYARLTVERFYKPWLKWNAIYYRTNKGKEALNAVKIMHSFT 252 Query: 263 KKVIKRKKEE 272 +KVI++K+ E Sbjct: 253 EKVIRQKQAE 262 >UniRef50_Q179B7 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 543 Score = 198 bits (483), Expect = 3e-49 Identities = 139/535 (25%), Positives = 257/535 (48%), Gaps = 22/535 (4%) Query: 23 VLLVPAVILWYAYWRM-SRRRLYELADKLNXXX--XXXXXXNALEFVGGSADIFRNIVQK 79 +L V ++ W + S+RR Y AD L AL F D F +V+ Sbjct: 2 LLAVTVIVGLITIWLLLSQRRRYRFADSLPQLKPWFPVVGNGALMFGKSDVDRFDVLVKI 61 Query: 80 SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139 DYD +V++W GP++L+F P V+ +L+S ++K Y F GL S Sbjct: 62 FRDYDR--MVRVWAGPKMLLFTSHPDLVQQLLTSPACLEKPFLYSF--AGFEQGLFTSKY 117 Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEIL 197 + WRS RK + +F+L +L FI +F +R +V+ L + + + H + S CT+E+ Sbjct: 118 KLWRSMRKRLNSSFNLRILHGFIPVFVQCARKMVEDLNENPDGTVVSMHKFTSVCTLEMA 177 Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257 T +G S T+ + E+ + R + L P++++ T Y + + + Sbjct: 178 CGTTLG-SDITRREGKEEFVHGLDIAFGEAARRMVSVHLYPNIVYHLTKYHRELVQARGV 236 Query: 258 IHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXX 317 + +V G S++ + + + L+ + + + Sbjct: 237 VCDFFSRVSLFPP---FFGVIMSHIIDCCMFYFQLVTERRNTMSLNCNKKTNEEELDF-- 291 Query: 318 XXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 377 +K +D LL ++ G + SD EI++ + ++ +DT+ + + ++ Sbjct: 292 ----DRKPKILIDQLLSVNRDGKSFSDTEIEDNIYAVITGANDTSGLLIAHACLFLCFYK 347 Query: 378 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 437 DI++K+ E+ + + + + + ++ YLE+ L E LR P P I+R+ EI + Sbjct: 348 DIEEKLFTEIMEFMPNEEFEINPESLKQLSYLEKFLKECLRHCPVAPNISRENMSEIEI- 406 Query: 438 SNGKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496 +G K+P G ++ Y LHRR D++ P+ +KFDP+ F ERS NRH +A++PFS G R Sbjct: 407 -DGMKVPPGNIFIMNFYALHRRKDIWGPDADKFDPEQFSEERSRNRHPFAYLPFSGGNRI 465 Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 C+G +YAM +KV+L ++RNF+ ++++ + + D+ +K +++ RK Sbjct: 466 CIGWRYAMFSMKVMLIYLIRNFQFETEIRPEQVRYRHDLTMKLPFEHMIKVTRRK 520 >UniRef50_Q16IS6 Cluster: Cytochrome P450; n=12; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 510 Score = 196 bits (477), Expect = 2e-48 Identities = 100/231 (43%), Positives = 143/231 (61%), Gaps = 5/231 (2%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 KKR A LD LL + Q + I + I+E+VDT FEGHDTTAA F + +QD+ Sbjct: 282 KKRYAMLDSLLLAEQKQL-IDEAGIREEVDTFAFEGHDTTAAALVFIFFTLAREPAVQDR 340 Query: 383 VIEELDQIFGD---SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 + E+ Q++ + S R T QD EMK+L+R L E LRL+PPV I+R ++++I L + Sbjct: 341 IYREILQVYSNKPQSSRAFTPQDYSEMKFLDRALKECLRLWPPVTFISRSISEDIIL-DD 399 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G IPAG I +H P+ +P+P +FD D FLPE+ R+ YA+VPFSAGPR+C+G Sbjct: 400 GSLIPAGCVANIHIMDMHHDPEQFPDPERFDADRFLPEQVDRRNPYAYVPFSAGPRNCIG 459 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +KYAM++LKV++ L FRV+ K D AD++L+ +VR + R Sbjct: 460 QKYAMMELKVVVVNALLKFRVLPVTKLEDINFVADLVLRSTNPIEVRFERR 510 Score = 98.3 bits (234), Expect = 5e-19 Identities = 63/195 (32%), Positives = 95/195 (48%), Gaps = 5/195 (2%) Query: 90 KIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148 + W L V + R+ E ILSS IDK+ Y+F P+LG GLL S G KW R++ Sbjct: 76 RFWFSSTLYVLNVVRVREAEHILSSTRNIDKSRFYKFLHPFLGLGLLNSNGSKWMHRRRI 135 Query: 149 IAPTFHLNVLKSFIDLFNANS---RAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVS 205 + P+FH N+L F F A +D+ + MS+ T+ + ET+MGV Sbjct: 136 LTPSFHFNILNGFHHTFVEECDQLLATIDEHVDKGVPTALQPVMSKFTLNTICETSMGVK 195 Query: 206 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKV 265 ST + Y + ++ ++L R + WL D L + T Y KLL +H T + Sbjct: 196 LSTVSGADV-YRTKLYEIGEVLVHRLMRPWLLNDFLCRLTGYKAAFDKLLLPVHLFTTGI 254 Query: 266 IKRKKEEFASGKKPS 280 I K+++F +PS Sbjct: 255 INMKRKQFQESLEPS 269 >UniRef50_UPI0000E46144 Cluster: PREDICTED: similar to ENSANGP00000019301; n=5; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ENSANGP00000019301 - Strongylocentrotus purpuratus Length = 469 Score = 195 bits (475), Expect = 3e-48 Identities = 85/178 (47%), Positives = 127/178 (71%), Gaps = 2/178 (1%) Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 ++KR+AFLDLLL+ + + E I+E+VDT MFEGHDTTAA ++ L ++G H +Q Sbjct: 280 KRKRIAFLDLLLQMHREDATFTLEAIREEVDTFMFEGHDTTAAAVNWALLLIGQHPTVQA 339 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 ++ +E+DQ+FGDS+RP+T D E+ YL + E+LRL P VP I R ++++I + NGK Sbjct: 340 RLHDEIDQVFGDSERPITSDDLSELSYLSCVVKESLRLLPSVPGIGRDLDEDIIV--NGK 397 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 +P G ++ ++ Y +H P+ +P+P +FDPD FLPE S RH +AF+PFSAGPR+C+G Sbjct: 398 VVPKGASVFLSIYGIHHDPEQFPDPERFDPDRFLPENSTKRHPFAFIPFSAGPRNCIG 455 Score = 149 bits (362), Expect = 1e-34 Identities = 78/228 (34%), Positives = 124/228 (54%), Gaps = 5/228 (2%) Query: 42 RLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHES--VVKIWIGPRLLV 99 R++ L K + N L+F + F V Y H+S V+++W GP +V Sbjct: 31 RIFLLISKFDGPPAVPIFGNTLQFKSDPREHFLYDVGVREKYRHQSGGVIRMWFGPLPIV 90 Query: 100 FLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLK 159 +Y+ E +++S +I+K EY F +PWLG GLL S GQKW RKL+ PTFH ++L+ Sbjct: 91 LIYNAVHCEALMNSSRHINKGTEYTFMEPWLGKGLLTSGGQKWFHRRKLLTPTFHFSILQ 150 Query: 160 SFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEY 216 SF+++FN S +V KL K E+ + ++ C ++I+ +TAMG + Q + EY Sbjct: 151 SFMEVFNEQSMILVKKLGKFADESETVNIFPLVTHCVLDIICDTAMGKRTNAQSDNENEY 210 Query: 217 AMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264 AV +M ++ R L PD ++ TD K+ K L I+HG+ ++ Sbjct: 211 VKAVGRMSHLIVSRIRNFMLWPDWIYNRTDAGKDHEKALQILHGMIQE 258 >UniRef50_Q9N574 Cluster: Cytochrome p450 family protein 31A3; n=4; Nematoda|Rep: Cytochrome p450 family protein 31A3 - Caenorhabditis elegans Length = 511 Score = 195 bits (475), Expect = 3e-48 Identities = 96/227 (42%), Positives = 148/227 (65%), Gaps = 4/227 (1%) Query: 325 RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVI 384 RLAFLDLLLE +SG + + +++ +VDT MFEGHDTT+ G + + ++G H ++Q KV Sbjct: 284 RLAFLDLLLEMVKSG-QMDETDVQAEVDTFMFEGHDTTSTGLMWAIHLLGNHPEVQRKVQ 342 Query: 385 EELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIP 444 ELD++ GD D VT + MKYLE L E LRL+P VPII R+++ + + G IP Sbjct: 343 AELDEVMGD-DEDVTIEHLSRMKYLECALKEALRLFPSVPIITRELSDDQVI--GGVNIP 399 Query: 445 AGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAM 504 G T ++ Y +HR P + +P+ FDPD FLPE S R +AF+PFSAG R+C+G+++A+ Sbjct: 400 KGVTFLLNLYLVHRDPSQWKDPDVFDPDRFLPENSIARKSFAFIPFSAGSRNCIGQRFAL 459 Query: 505 LKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 ++ KVI++ +LRNF V + + + + +II++ ++L R+ Sbjct: 460 MEEKVIMAHLLRNFNVKAVELMHEVRPKMEIIVRPVTPIHMKLTRRR 506 Score = 105 bits (251), Expect = 4e-21 Identities = 77/268 (28%), Positives = 119/268 (44%), Gaps = 22/268 (8%) Query: 23 VLLVPAVIL-WYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSA 81 VLL A I+ W Y + R+ + LN + L ++ Sbjct: 8 VLLASATIIAWLLYKHL---RMRQALKHLNQPRSYPIVGHGLVTKPDPEGFMNQVIGMGY 64 Query: 82 DYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQK 141 Y + +WIGP + LY VE I SS +++K Y +PWLG +L S ++ Sbjct: 65 LYPDPRMCLLWIGPFPCLMLYSADLVEPIFSSTKHLNKGFAYVLLEPWLGISILTSQKEQ 124 Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEILLE 199 WR RKL+ PTFH ++LK F+ +FN S+ +V K+ D ++ CT++I+ E Sbjct: 125 WRPKRKLLTPTFHYDILKDFLPIFNEQSKILVQKMCSLGAEEEVDVLSVITLCTLDIICE 184 Query: 200 TAMGVSKSTQDQSGFEYAMAVMKMCDILHLR--HTKIWLR--------------PDLLFK 243 T+MG + Q EY AV + ++ R + +W +LF Sbjct: 185 TSMGKAIGAQLAENNEYVWAVHTINKLISKRTNNPLMWNSFIYNLYDSFIIKKVNSILFF 244 Query: 244 FTDYAKNQTKLLDIIHGLTKKVIKRKKE 271 T+ + K L I+H TKKVI +KE Sbjct: 245 RTEDGRTHEKCLRILHDFTKKVIVERKE 272 >UniRef50_Q9N4Q5 Cluster: Cytochrome p450 family protein 32B1; n=2; Caenorhabditis|Rep: Cytochrome p450 family protein 32B1 - Caenorhabditis elegans Length = 516 Score = 194 bits (473), Expect = 5e-48 Identities = 102/237 (43%), Positives = 155/237 (65%), Gaps = 5/237 (2%) Query: 322 QKKRLAFLDLLLESSQSGVAI-SDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 + K+LAFLD LL+S + I +DE I+E+VDT MFEGHDTT++G +F + +G + Q Sbjct: 280 ETKKLAFLDYLLKSQEEHPDILTDEGIREEVDTFMFEGHDTTSSGITFAVWFLGQFPEYQ 339 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 +V +ELD+IFG D +R +D +M YLE+C+ ETLR+ PPVP ++R++ +++ +P Sbjct: 340 QRVHDELDEIFGEDFERIPNSEDIQKMVYLEQCIKETLRMTPPVPFVSRKLTEDVKIPHA 399 Query: 440 GKK---IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496 K +PAG +I + + + P +F P++F PER A R +AFVPFSAGPR+ Sbjct: 400 TKPDLLLPAGINCMINIITIMKDARYFERPYEFFPEHFSPERVAAREPFAFVPFSAGPRN 459 Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRM 553 C+G+K+A+L+ KV+LS I RNF V S K + ++ILK G QV L+ R+++ Sbjct: 460 CIGQKFALLEEKVLLSWIFRNFTVTSMTKFPEEMPIPELILKPQFGTQVLLRNRRKL 516 Score = 128 bits (308), Expect = 5e-28 Identities = 69/203 (33%), Positives = 115/203 (56%), Gaps = 7/203 (3%) Query: 84 DHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWR 143 D+ V+K+W+GP V + +++L S V I K+ +Y K W+G+GLLISTG KWR Sbjct: 79 DNCGVLKLWLGPIPAVNIARGEIAKIVLDSSVNISKSSQYNKLKEWIGDGLLISTGDKWR 138 Query: 144 SHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLET 200 S RK++ TFH VLK + +F A + +V+ L+ A+N FD Y+ C ++I+ ET Sbjct: 139 SRRKMLTQTFHFAVLKEYQKIFGAQGKILVEVLQLRANNKFSFDIMPYIKRCALDIICET 198 Query: 201 AMGVSKSTQDQSGFEYAMAVMKMCDIL--HLRHTKIWLRPDLLFKFTDYAKNQTKLLDII 258 AMG S S+Q + EY +V ++ +I+ + + + WL+P + + F D + + + Sbjct: 199 AMGCSISSQRGANDEYVNSVRRLSEIVWNYEKAPQFWLKP-IWYLFGD-GFEFNRHVKLT 256 Query: 259 HGLTKKVIKRKKEEFASGKKPSN 281 T+ VI+ +K+E + N Sbjct: 257 TDFTRDVIENRKKELKTHNSEQN 279 >UniRef50_Q7YSZ3 Cluster: P450 enzyme precursor; n=1; Rhodnius prolixus|Rep: P450 enzyme precursor - Rhodnius prolixus (Triatomid bug) Length = 512 Score = 192 bits (467), Expect = 3e-47 Identities = 96/230 (41%), Positives = 148/230 (64%), Gaps = 3/230 (1%) Query: 323 KKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 K + AFL++L++ +S ++D++I+E+VD MF GHDTTA+ F L ++G H +Q+ Sbjct: 283 KGKKAFLNILIDLEDKSKGTLTDKDIREEVDNFMFAGHDTTASCIMFTLYLLGRHPHVQE 342 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 K EEL +IFG+SDR V +D M YLE + E++R+YPP P +R + Q++ L + Sbjct: 343 KAFEELYEIFGESDREVNNKDLHGMHYLEMIIKESIRIYPPAPYFSRNLIQDLVL-KDKT 401 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 +P G + I + +HR P +PNP FDP+ F E RH YA++PFSAGPR+C+G+K Sbjct: 402 VLPEGANVGIFAFIMHRDPKYFPNPEVFDPERFSAENCKKRHPYAYLPFSAGPRNCIGQK 461 Query: 502 YAMLKLKVILSTILRNFRVISDLKE-SDFKLQADIILKRAEGFQVRLQPR 550 +AM++LKV+LSTILR ++ S E S L I+LK + ++++ R Sbjct: 462 FAMMELKVVLSTILRFAKIESVNDEISARSLTPLILLKPCDPIRIKVFSR 511 Score = 124 bits (299), Expect = 6e-27 Identities = 63/202 (31%), Positives = 112/202 (55%), Gaps = 2/202 (0%) Query: 84 DHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWR 143 ++ +V W+ V+L+DP D+EVIL+S I K EY PW+ +GL++S G+KW Sbjct: 73 EYARLVAFWLAGIPTVWLFDPDDLEVILASSQAIQKGNEYHCLFPWMQDGLVLSKGEKWH 132 Query: 144 SHRKLIAPTFHLNVLKSFIDLFNANSRAVV-DKLKKEASNFDCHDYMSECTVEILLETAM 202 RKL+ P FH +L++ + N N+R ++ + LKKE F + + CT++++ ETAM Sbjct: 133 QRRKLLTPAFHFKILENNMQSLNKNARCLLRNMLKKEGRPFVTQELVVRCTLDVISETAM 192 Query: 203 GVSKSTQD-QSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261 G + + Q+ + +Y AV + C + R ++ D ++ T + +K L +H Sbjct: 193 GHALNLQEREENNDYLNAVERACSLTFDRSKNVFYSNDGVYFLTLDGRKFSKNLKYLHNF 252 Query: 262 TKKVIKRKKEEFASGKKPSNLN 283 ++ +I+ +K ++ KK S N Sbjct: 253 SENIIQNRKLKYLLEKKYSENN 274 >UniRef50_UPI0000D5646A Cluster: PREDICTED: similar to CYtochrome P450 family member (cyp-31A3); n=2; Tribolium castaneum|Rep: PREDICTED: similar to CYtochrome P450 family member (cyp-31A3) - Tribolium castaneum Length = 349 Score = 191 bits (466), Expect = 4e-47 Identities = 95/231 (41%), Positives = 149/231 (64%), Gaps = 6/231 (2%) Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 ++KRL L+ LL+ S+ I +++++ TI+ G +TTA L ++GI+ +IQ Sbjct: 123 REKRL--LNHLLKLSKINAKIDQTALEDEIQTILLTGSETTALTVGLTLIILGIYPEIQK 180 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 K+ +ELD IFG DR T +D M+YLER + ETLR PVP + R NQ+ITL SN Sbjct: 181 KIGKELDVIFGKDDRVPTLEDINRMEYLERVIKETLRFLTPVPFMLRTNNQDITLDSN-- 238 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 IPAG+ ++I + +H++P+ + NPN+FDPD FLPE S+ R AF+PFS+GPR+C+G K Sbjct: 239 TIPAGSCIMIPIFHIHKKPEYWKNPNEFDPDRFLPENSSKRPRCAFIPFSSGPRNCIGFK 298 Query: 502 YAMLKLKVILSTILRNFRVISD--LKESDFKLQADIILKRAEGFQVRLQPR 550 Y M+ +KV+L+ ILR + V++ K D ++ ++ K G +++L+ + Sbjct: 299 YGMMSVKVLLAVILRKYTVVATEYKKVEDIEMLFYVVNKPISGCKIKLEKK 349 Score = 42.7 bits (96), Expect = 0.025 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 5/73 (6%) Query: 128 PWLGNGLLISTGQK---WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SN 182 P G+ + G K W+S RK+I PTF+ N+L SF+++F ++ + + L++ + Sbjct: 43 PIFGSAHYLMGGHKVDVWKSRRKMINPTFNPNILNSFVEIFGRHAFYLTNALEENCGKDS 102 Query: 183 FDCHDYMSECTVE 195 FD + CT + Sbjct: 103 FDILPKLFRCTFD 115 >UniRef50_Q9VS79 Cluster: Cytochrome P450 4d8; n=6; Schizophora|Rep: Cytochrome P450 4d8 - Drosophila melanogaster (Fruit fly) Length = 463 Score = 190 bits (464), Expect = 6e-47 Identities = 93/235 (39%), Positives = 156/235 (66%), Gaps = 8/235 (3%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G K+R+A LD+LL S+ G ++++EI+E+VDT MFEGHDTT + SF L + H ++Q Sbjct: 231 GSKRRMALLDVLLMSTVDGRPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQ 290 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIAR--QVNQEITLP 437 K++EE+ Q+ G D RPV+ +D E+KY+E + E+LR+YPPVPI+ R Q + + T Sbjct: 291 AKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHS 350 Query: 438 SNGK-KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496 +G IPAG+ ++I + +HR+P+ +PNP++F P+ E + + +PFSAGPR+ Sbjct: 351 VHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH--ENGSRVAPFKMIPFSAGPRN 408 Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 C+G+K+A L++K++L+ I+R + ++ + +I+L+ GFQ+ ++ RK Sbjct: 409 CIGQKFAQLEMKMMLAKIVREYELLP--MGQRVECIVNIVLRSETGFQLGMRKRK 461 Score = 120 bits (288), Expect = 1e-25 Identities = 72/224 (32%), Positives = 119/224 (53%), Gaps = 6/224 (2%) Query: 90 KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149 ++WI RLL+ D E +LSS ++ K Y+ WLGNGLL+S G+ W RK+I Sbjct: 28 RVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRRKII 87 Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SNFDCHDYMSECTVEILLETAMGVSKS 207 PTFH ++L+ F+++F+ S V +L ++A + FD + + ++I+ ETAMG Sbjct: 88 TPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIAETAMGTKIY 147 Query: 208 TQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFT-DYAK-NQTKLLDIIHGLTKKV 265 Q YA AV + +L R ++L+ +LLF T + K QT+L+ + T KV Sbjct: 148 AQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTIKV 207 Query: 266 IKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSG 309 I+++++ A + S L +TA S ++ ++ L G Sbjct: 208 IEKRRQ--ALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDG 249 >UniRef50_Q170T0 Cluster: Cytochrome P450; n=12; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 505 Score = 190 bits (462), Expect = 1e-46 Identities = 94/236 (39%), Positives = 152/236 (64%), Gaps = 8/236 (3%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G +K++AFLD+LL+++ G + D E++E+VDT MFEGHDTT + SF + ++ H D+Q Sbjct: 274 GIRKKVAFLDMLLQATVDGRPLDDLEVREEVDTFMFEGHDTTTSAISFLIGILAKHPDVQ 333 Query: 381 DKVIEELDQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQV--NQEITLP 437 KV +E+ + GD + VT ++ YL+ + ETLRLYP VPI R + NQEI Sbjct: 334 QKVYDEVRNVIGDDLNVSVTLSMLNQLNYLDLVIKETLRLYPSVPIYGRMLLENQEI--- 390 Query: 438 SNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRS 496 NG PAG+ L I Y + R P+ + NP +F P+ F E SA + + Y +VPFSAGPR+ Sbjct: 391 -NGTVFPAGSNLAIFPYFMGRDPEYFENPLEFRPERFAVETSAEKANPYRYVPFSAGPRN 449 Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552 C+G+K+A+ ++K ++S ++R++ V+ + + ++ A+++L+ G VR++ R R Sbjct: 450 CIGQKFAVAEIKSLISKLVRHYEVLPPKQPNSERMIAELVLRPEGGVPVRIRSRVR 505 Score = 159 bits (387), Expect = 1e-37 Identities = 90/262 (34%), Positives = 142/262 (54%), Gaps = 6/262 (2%) Query: 18 INLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIV 77 I L V+++ + Y Y + + R Y A K+ N++++ S F V Sbjct: 3 ILLASVVVLSIGLAVYFYQQFANRLHY--AAKIGGPKGYPLLGNSIQYGTKSPVEFLQEV 60 Query: 78 QKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIS 137 QK+ + + ++WIGP L+ + D + VE ILSS +DK+ +Y F +PWLGNGLL S Sbjct: 61 QKTNEQCGK-FYRLWIGPDLIFPITDAKLVEAILSSQKLLDKSVQYDFIRPWLGNGLLTS 119 Query: 138 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSECTV 194 TG+KW S RK+I PTFH +L+ F+++F+ S V +LK +A +FD ++ C + Sbjct: 120 TGRKWHSRRKIITPTFHFKILEQFVEIFDQQSNIFVGQLKSKAQSGEDFDVFPVVTLCAL 179 Query: 195 EILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKL 254 +++ E+AMG + Q S +Y AV M + R K + R + F FT Y + Q K Sbjct: 180 DVICESAMGTKVNAQLNSDSKYVRAVKDMATVAMARSFKAFARFNFTFYFTPYRRMQDKA 239 Query: 255 LDIIHGLTKKVIKRKKEEFASG 276 L ++H T VI+ ++ E A G Sbjct: 240 LKVLHDYTDSVIRSRRLELAKG 261 >UniRef50_Q9V7G5 Cluster: Probable cytochrome P450 4aa1; n=5; Diptera|Rep: Probable cytochrome P450 4aa1 - Drosophila melanogaster (Fruit fly) Length = 514 Score = 190 bits (462), Expect = 1e-46 Identities = 90/230 (39%), Positives = 142/230 (61%), Gaps = 2/230 (0%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G +R LD ++E S+S ++E+I + T M G D+ A +F L ++ + + Q Sbjct: 280 GNSERKCLLDHMIEISESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQ 339 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 D+ + EL IF DS+R T D EM+Y+E C+ E LRLYP VP+IAR++ +E+ L + Sbjct: 340 DRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKH- 398 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +PAG+ + I Y HR +YP+P KF P+ F PE S NRH YAF+PFSAGPR C+G Sbjct: 399 -TLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGN 457 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 ++A++++K I+S +LR+++++ ++ I L+ + G VRL+ R Sbjct: 458 RFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRLKER 507 Score = 109 bits (262), Expect = 2e-22 Identities = 65/205 (31%), Positives = 115/205 (56%), Gaps = 6/205 (2%) Query: 71 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 130 D+ R K+ D + S+V+IW+ + +P D++VILSS + +K YR +L Sbjct: 71 DLMRRCAGKAFDL-YGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFL 129 Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SNFDCHDY 188 G+GL+ S+G KW +HR+LI P FH N+L+ FID F S+++ + L EA + + Y Sbjct: 130 GDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKY 189 Query: 189 MSECTVEILLETAMGV--SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 246 ++ C ++IL E +GV K QD + E + + ++ R T+ WL D ++ +T Sbjct: 190 VNNCVLDILNEAVLGVPIKKRGQDVAMMEDS-PFRQGKIMMPARFTQPWLLLDGIYHWTK 248 Query: 247 YAKNQTKLLDIIHGLTKKVIKRKKE 271 A ++ ++ T+K+I+R+++ Sbjct: 249 MANDELNQKKRLNDFTRKMIQRRRQ 273 >UniRef50_Q8ISJ7 Cluster: Cytochrome P450 CYP4L4; n=4; Noctuidae|Rep: Cytochrome P450 CYP4L4 - Mamestra brassicae (Cabbage armyworm) Length = 492 Score = 189 bits (460), Expect = 2e-46 Identities = 90/232 (38%), Positives = 154/232 (66%), Gaps = 8/232 (3%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G K + FLDLLL + G I DE ++E+VDT MFEGHDTT +G + L + +D+Q Sbjct: 268 GTKNKHTFLDLLLLAEIDGKKIDDESVREEVDTFMFEGHDTTTSGIVYTLHCLSKRRDVQ 327 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 +K+ EEL IFG + R T+ + +MKYLE + E++RL+PPVP+I R++ ++ + Sbjct: 328 EKIYEELKTIFGSEIHRDPTYHELQQMKYLELVIKESMRLFPPVPLIERRIMKDCEV--G 385 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G K+ GT++V+ +++ R+PD++ +P +F P+ F + ++ ++++ FSAGPR+C+G Sbjct: 386 GLKLVKGTSVVMNIFQIQRQPDLFDDPLEFRPERF---EAPLKNPFSWLAFSAGPRNCIG 442 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 +K+AM++LK+ +S I++NF ++ +E + L AD++L+ G V+ PRK Sbjct: 443 QKFAMMELKITISEIVKNFFILPAAEEPE--LSADLVLRSKNGVNVKFLPRK 492 Score = 126 bits (303), Expect = 2e-27 Identities = 88/296 (29%), Positives = 144/296 (48%), Gaps = 17/296 (5%) Query: 20 LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79 +F V+++ ++ W + R+SRR L NA FV S++ F N+VQ+ Sbjct: 6 VFVVVVLALLVSWISLVRVSRRFNVPGPSPLPLVG------NAHLFVVKSSE-FLNLVQR 58 Query: 80 -SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST 138 S Y H V + P V + + E ++SS +I K Y F WLG GLL +T Sbjct: 59 LSEKYGHAFRVHFFSTP--YVVICHSKYAEPLVSSTEHITKGRSYSFLTCWLGQGLLTAT 116 Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEI 196 GQ+W+SHRK + P FH N+L++F+ +F N R + +K++ A D ++ ++ Sbjct: 117 GQRWKSHRKFLTPAFHFNILQNFLPVFCKNQRILTEKIRGMADGRPIDMFPIIALAALDN 176 Query: 197 LLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLD 256 + E+ MGV Q S EY ++ ++ I+ +R + D +F Y Q K L Sbjct: 177 VNESIMGVCMDAQKHSQSEYVKSIEELSAIVTMRMQIPFFGEDAIFNLLPYKTKQDKALK 236 Query: 257 IIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPST-GKLTSVEGLSFGQSSGLK 311 ++HG T KVI ++ E K +N+ +S+ T K T ++ L + G K Sbjct: 237 VLHGQTNKVINARRAEL----KKANITTLNDSSDIGTKNKHTFLDLLLLAEIDGKK 288 >UniRef50_A1BPS3 Cluster: CYP4BG1; n=1; Ips paraconfusus|Rep: CYP4BG1 - Ips paraconfusus Length = 498 Score = 188 bits (459), Expect = 3e-46 Identities = 94/227 (41%), Positives = 137/227 (60%), Gaps = 5/227 (2%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 +K LDLLL +I E I+E+VDT MFEGHDTT+A F L + + IQ+K Sbjct: 275 RKIYKMLDLLLHEKLQFGSIDYEGIREEVDTFMFEGHDTTSAALVFLLHNLASNLAIQEK 334 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 V +E+ + +R TFQ + Y +R + E+LRLYP VP I+R +++ + G Sbjct: 335 VRQEIKTV----ERIPTFQTLQNLPYTDRVIKESLRLYPSVPFISRIASEDF-ITHTGYS 389 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 I GT L + + LHR P++YP+P FDPD FLPE+ RH +A++PFSAGPR+C+G+K+ Sbjct: 390 ISKGTVLYMHIFDLHRNPEIYPDPLTFDPDRFLPEKVKERHPFAYLPFSAGPRNCIGQKF 449 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549 AML+LK +L +L FR+ D + Q D+IL+ ++ QP Sbjct: 450 AMLELKAVLWGLLHKFRLTLDPSTTQINFQVDLILRTQGEIKINFQP 496 Score = 118 bits (285), Expect = 3e-25 Identities = 83/297 (27%), Positives = 150/297 (50%), Gaps = 17/297 (5%) Query: 69 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP 128 S ++F + + DY + +I I +V + P D+E+ILS ++ K+ Y+F + Sbjct: 52 SGELFDQLRNFARDYG--PIYRISIPFLDIVNFFHPADLEIILSQKKHMKKSLLYQFLEG 109 Query: 129 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK------KEASN 182 WLG GLL STG KW+ RKL+ FH N+L+ F+ +FN + +V +++ + + Sbjct: 110 WLGKGLLTSTGSKWQFRRKLLTQAFHFNILQKFVRVFNEETTHLVKRIEEINLTGQSQAG 169 Query: 183 FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLF 242 ++ T++ + ET++GVS + + ++ Y + KM D L R K W + ++ Sbjct: 170 ISVLPLITHLTLQSVTETSLGVS-NIEKETLKAYRENIYKMGDFLIDRLRKPWRLFNFIY 228 Query: 243 KFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSV--- 299 FT+ +K + ++ +H T +VIK ++E S K S + T+T S K+ + Sbjct: 229 HFTEASKQEQLTINKLHQFTYQVIKEREEVLQSDKTQSVM--TSTYSGRKIYKMLDLLLH 286 Query: 300 EGLSFG--QSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTI 354 E L FG G++ G A L LL + S +AI E++++++ T+ Sbjct: 287 EKLQFGSIDYEGIREEVDTFMFEGHDTTSAALVFLLHNLASNLAI-QEKVRQEIKTV 342 >UniRef50_Q16I47 Cluster: Cytochrome P450; n=7; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 506 Score = 188 bits (457), Expect = 4e-46 Identities = 88/230 (38%), Positives = 145/230 (63%), Gaps = 4/230 (1%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 K+++ FLDLLL + +G +S E+I+E+VDT MFEGHDTT +G SF L + +QD+Q K Sbjct: 278 KRKMTFLDLLLNVTVNGKPLSREDIREEVDTFMFEGHDTTTSGISFTLWHLAKYQDVQQK 337 Query: 383 VIEELDQIFGDS--DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 + EE+D++ G + +T E+ YL+ + E+LRL PPVPII R + +++ + NG Sbjct: 338 LFEEIDRVLGKDKVNAELTNLQIQELDYLDMVVKESLRLIPPVPIIGRTLVEDMEM--NG 395 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 IPAGT + I Y +HR P ++ ++F P+ F + R Y F+PFSAG R+C+G+ Sbjct: 396 VTIPAGTQISIKIYNIHRNPKIWEKSDEFIPERFSKTNESKRGPYDFIPFSAGSRNCIGQ 455 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +YAM++LKV + ++ +F+V+ + + D++++ G ++L R Sbjct: 456 RYAMMELKVTIIKLIASFKVLPGDSMDKLRFKTDLVIRPDNGIPIKLVER 505 Score = 128 bits (308), Expect = 5e-28 Identities = 81/230 (35%), Positives = 124/230 (53%), Gaps = 9/230 (3%) Query: 65 FVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR 124 F+G + +I+ E + I L++ L ++VE +L + I K+ Y Sbjct: 48 FIGKTIPDIWDIITDLHKKHGEDIAIIAAFNELVMDLSSSKNVEKVLLAKS-IKKSFAYD 106 Query: 125 FFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SN 182 F +PWLG GLLISTG+KW RK+I PTFH ++L+ F+++FN + +V KLK +A Sbjct: 107 FLEPWLGTGLLISTGEKWFQRRKIITPTFHFSMLEGFLEVFNKEANILVSKLKAKAGKDE 166 Query: 183 FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLR--PDL 240 FD +DY++ ++ + ET+MGV + QD EYA+AV +M + LR LR P L Sbjct: 167 FDIYDYVTLYALDSICETSMGVQINAQDDPNNEYAVAVKQMSTFI-LRRVFSILRTFPSL 225 Query: 241 LFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSE 290 F + +AK Q K++ +H T VI ++ K+ SN N T E Sbjct: 226 FFLY-PFAKEQKKVILKLHNFTNSVIDARRAMLE--KEKSNKNVTFDLQE 272 >UniRef50_Q9VMS9 Cluster: Probable cytochrome P450 4ac1; n=5; Sophophora|Rep: Probable cytochrome P450 4ac1 - Drosophila melanogaster (Fruit fly) Length = 509 Score = 187 bits (455), Expect = 8e-46 Identities = 93/230 (40%), Positives = 145/230 (63%), Gaps = 4/230 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G+K+R A LD LL + G I + I ++V+T MFEG+DTT+ F L M+ +H+D+Q Sbjct: 282 GRKQRYAMLDTLLAAEADG-QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQ 340 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 K EE++ + DSD FQ ++ YLE + E+LR++P VP I RQ +E + NG Sbjct: 341 KKCYEEVENLPEDSDDISMFQFN-KLVYLECVIKESLRMFPSVPFIGRQCVEETVV--NG 397 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +P T + I Y + R P +P P+ F PD FLPE + NRH +A+VPFSAG R+C+G+ Sbjct: 398 MVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNRHPFAYVPFSAGQRNCIGQ 457 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 K+A+L++KV+L+ ++RNF+++ + D + I+L+ E +V+L R Sbjct: 458 KFAILEMKVLLAAVIRNFKLLPATQLEDLTFENGIVLRTQENIKVKLSKR 507 Score = 95.5 bits (227), Expect = 3e-18 Identities = 55/172 (31%), Positives = 92/172 (53%), Gaps = 4/172 (2%) Query: 104 PRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFID 163 P + E + S I K Y +P+LG+GLLIST KW S RK + P FH NVL+SF+ Sbjct: 101 PEEAEEVFQSTKLITKNVVYELIRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLG 160 Query: 164 LFNANSRAVVDKLKKEA-SNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMK 222 +F + ++ L+K + + + + T+ + ETA+GV K G EY A+ Sbjct: 161 IFKEECKKFLNVLEKNLDAELELNQVIPPFTLNNICETALGV-KLDDMSEGNEYRKAIHA 219 Query: 223 MCDILHLRHTKIWLRPD-LLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEF 273 + ++L R + + F + DY K+ + L I+H + ++I+RK+++F Sbjct: 220 IEEVLIQRVCNPLMYYNWYFFVYGDYRKH-LQNLRIVHDFSSRIIERKRQQF 270 >UniRef50_P33269 Cluster: Cytochrome P450 4d1; n=11; Diptera|Rep: Cytochrome P450 4d1 - Drosophila melanogaster (Fruit fly) Length = 512 Score = 186 bits (454), Expect = 1e-45 Identities = 92/234 (39%), Positives = 153/234 (65%), Gaps = 7/234 (2%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G K+++AFLD+LL+S+ +S+ +I+E+VDT MFEGHDTT++ FF + H + Q Sbjct: 280 GAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQ 339 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 K EE+ + G D PV+++ ++ Y++ C+ ETLR+YP VP++ R+V ++ + N Sbjct: 340 KKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEI--N 397 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCV 498 GK IPAGT + I+ L RR +++ PN F P+ F +A + + YA++PFSAGPR+C+ Sbjct: 398 GKLIPAGTNIGISPLYLGRREELFSEPNSFKPERFDVVTTAEKLNPYAYIPFSAGPRNCI 457 Query: 499 GRKYAMLKLKVILSTILRNFRV--ISDLKESDFKLQADIILKRAEGFQVRLQPR 550 G+K+AML++K I++ +LR++ V + D E L A++IL+ E +++ R Sbjct: 458 GQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPV-LIAELILRTKEPLMFKVRER 510 Score = 171 bits (416), Expect = 4e-41 Identities = 88/270 (32%), Positives = 148/270 (54%), Gaps = 7/270 (2%) Query: 24 LLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSA-DIFRNIVQKSAD 82 +L A+ + + + +RL +L + + F+G ++ + I + Sbjct: 8 ILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMET 67 Query: 83 YDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKW 142 Y + V+K+W+GP L V + +P+DVEV+L + + DKA EY+ +PWL GLL+S G+KW Sbjct: 68 YSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKW 127 Query: 143 RSHRKLIAPTFHLNVLKSFIDLFNANSRAVV-----DKLKKEASNFDCHDYMSECTVEIL 197 RK+I P FH +L F+++F SR ++ D+LK S F +D+++ CT++ + Sbjct: 128 HKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGESGFSLYDWINLCTMDTI 187 Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257 ETAMGVS + Q + EY AV + +LH R I R DL + T A+ + K L++ Sbjct: 188 CETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNV 247 Query: 258 IHGLTKKVIKRKKEE-FASGKKPSNLNETA 286 +H T+K+I +++EE G + N+ A Sbjct: 248 LHQFTEKIIVQRREELIREGSSQESSNDDA 277 >UniRef50_Q9XVA6 Cluster: Putative uncharacterized protein cyp-37A1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein cyp-37A1 - Caenorhabditis elegans Length = 508 Score = 186 bits (453), Expect = 1e-45 Identities = 89/231 (38%), Positives = 146/231 (63%), Gaps = 3/231 (1%) Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 + K+ AFLD+L+E + G + E+I+E+VDT MFEGHDTT+AG + L + + Q Sbjct: 281 ESKKKAFLDMLIEKKEEG-GLGYEDIREEVDTFMFEGHDTTSAGIGWSLWCLANCPEYQK 339 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 K EELD+IF + R + +D +MKYLE+C+ E LR+ P VP +AR V +E+ + +GK Sbjct: 340 KCHEELDEIFEGTSRECSVEDLKKMKYLEKCVKEALRMRPSVPQMARSVEEEVEI--DGK 397 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 +P G +++I+ + P +PN FDP+ F + + RH YA++PFSAGPR+C+G+K Sbjct: 398 ILPKGCSVMISPAFIQNNPRTFPNHEVFDPERFNEDEISKRHAYAYIPFSAGPRNCIGQK 457 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552 +AM + K ++S +LR F + +D+ + + I + + GF ++ R++ Sbjct: 458 FAMQEEKTVISWVLRRFHIHTDIGLLENMPLPETITRPSLGFPLKFTVRQQ 508 Score = 138 bits (334), Expect = 4e-31 Identities = 82/265 (30%), Positives = 135/265 (50%), Gaps = 14/265 (5%) Query: 17 AINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNI 76 A+ + YV+ + IL + RM RLY L K++ +F + + Sbjct: 9 ALVVIYVVFNLSKILKFVKERM---RLYHLMSKIDGPLALPLLGTTFQFKMDPVEFALQL 65 Query: 77 VQKSADYDHE--SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGL 134 +Y + S+ W+GP +V + P + +L S+ I+K+ EY F PWLG GL Sbjct: 66 YNWGLEYSTKGSSLAAFWMGPYPMVIVLTPEANKKVLESNALINKSSEYDIFLPWLGTGL 125 Query: 135 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKL-----KKEASNFDCHDYM 189 L+++G+KWR RK++ P+FH NVL F +FN+ S +++++ K + S D Y+ Sbjct: 126 LLASGEKWRGRRKMMTPSFHFNVLIDFQVVFNSQSMILLEQIENAAKKTDDSTIDAFPYI 185 Query: 190 SECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDIL--HLRHTKIWLRPDLLFKFTDY 247 C ++I+ ETAMG + S Q Y +AV +M + + R +W++P + + Y Sbjct: 186 KRCALDIICETAMGTTVSAQTNHTHPYVVAVNEMNSLAFKYQRMPWLWIKP--IRQLIGY 243 Query: 248 AKNQTKLLDIIHGLTKKVIKRKKEE 272 + + LDI+ TKKVI RK E Sbjct: 244 EADFQRNLDIVTSFTKKVIDRKLRE 268 >UniRef50_Q4R1I7 Cluster: Cytochrome P450; n=1; Papilio xuthus|Rep: Cytochrome P450 - Papilio xuthus Length = 506 Score = 186 bits (453), Expect = 1e-45 Identities = 88/230 (38%), Positives = 148/230 (64%), Gaps = 4/230 (1%) Query: 324 KRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383 K +FLDLL+E S +D E++E++ T+ G DTT + L ++ ++ +QDK+ Sbjct: 276 KTQSFLDLLIEFSGGENGYTDLELREEILTLTIAGTDTTGISIGYTLKLLAMYPKVQDKL 335 Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443 +EL +FG SDR + +D ++KYLER + E+LRLYPP P I R+V ++I+LPS G+ Sbjct: 336 YQELLDVFGTSDRRIVKEDLSKLKYLERIVKESLRLYPPGPFIIRKVLEDISLPS-GRVF 394 Query: 444 PAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 PAG+ ++ + LHR P + P+ FDPD FLPER +H +++PFS+GPR+C+G +Y Sbjct: 395 PAGSGAAVSIWGLHRDPKYWGPDAEVFDPDRFLPERFNLKHACSYIPFSSGPRNCIGYQY 454 Query: 503 AMLKLKVILSTILRNFRVISDLK--ESDFKLQADIILKRAEGFQVRLQPR 550 A++ +K +LS I+R ++++ + K + DI++K + +++ L+ R Sbjct: 455 ALMSMKTVLSAIVRRYKIMGEESGPVPHIKSKIDIMMKAVDDYKICLEKR 504 Score = 127 bits (307), Expect = 7e-28 Identities = 75/262 (28%), Positives = 133/262 (50%), Gaps = 6/262 (2%) Query: 20 LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXN-ALEFVGGSADIFRNIVQ 78 +F LL +V+L +++ RRRLY LA K+ A +F G + DI ++ + Sbjct: 1 MFLCLLCLSVVLGMVLFKLKRRRLYRLASKIPGSDDELPFIGLAHKFTGTTEDILNSLQK 60 Query: 79 KSAD-YDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIS 137 S + + +++ W+G L + DP DVEVIL + ++K + +RF + +GNGL+ + Sbjct: 61 YSYEAMKNNGILRGWLGHILYFIVVDPVDVEVILKTS--LEKDDLHRFIRNVIGNGLIFA 118 Query: 138 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVE 195 WR RK+ P F ++ +F+++F S +V L A N Y+ T++ Sbjct: 119 PVSIWRRRRKITVPAFSPKIVDTFMEVFAEQSEKLVSVLAACAGNGYIAMEPYLCRYTLD 178 Query: 196 ILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLL 255 + ET MG++ + Q+ Y A+ + +++ R +WL+PD L+KF +K+ K Sbjct: 179 SVCETTMGITTNAQNNPNAPYLKALKNILNLVCERIFHLWLQPDWLYKFFSQSKSHQKYT 238 Query: 256 DIIHGLTKKVIKRKKEEFASGK 277 + G +VI+ K+ E K Sbjct: 239 KEMQGFVDEVIQNKRREIKKEK 260 >UniRef50_A1BPR9 Cluster: CYP4BD1; n=1; Ips paraconfusus|Rep: CYP4BD1 - Ips paraconfusus Length = 504 Score = 186 bits (452), Expect = 2e-45 Identities = 91/232 (39%), Positives = 143/232 (61%), Gaps = 4/232 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G + RLAFLDLLLE+ G ++ E++++V+T MFEGHDTT++ +F L M+ H +Q Sbjct: 275 GIRTRLAFLDLLLEAKIDGTPLTKAELRDEVNTFMFEGHDTTSSAITFCLLMLATHPRVQ 334 Query: 381 DKVIEELDQIF-GDSDRP-VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438 DKV+ E +I GD T ++ +MKYLE + ETLRLYP VP+ +R++ +++ Sbjct: 335 DKVMAEQKEILEGDLKLAHPTSKELSQMKYLENVIKETLRLYPSVPLFSRKLGEDVEF-- 392 Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 G P G TLV+ Y HR PD++P P KF P+ F + +A+ PFSAG R+C+ Sbjct: 393 KGNLYPKGITLVLTPYATHRDPDIFPEPEKFLPERFEESEMLKINPFAYTPFSAGSRNCI 452 Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 G+K+AM+++K +S ++R+F++ E +L ++ L G ++ LQ R Sbjct: 453 GQKFAMMEIKSTVSKVVRHFKLEPAHPEHQIQLVSETTLNSKNGVKISLQAR 504 Score = 118 bits (285), Expect = 3e-25 Identities = 73/218 (33%), Positives = 116/218 (53%), Gaps = 10/218 (4%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGP-RLLVFLYDPRDVEVILSSHVYIDK 119 N L F+ GS I+Q + S+ GP +V DP +E+I SS +I K Sbjct: 47 NTLPFLKGSVVYLDLIMQGVKELGRTSLFHD--GPLSWVVITADPEFIELIYSSSTHITK 104 Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE 179 +Y +FK WLG GLLIS G KWR HRK+I PTFH ++L+ F+ +F+ V KL++ Sbjct: 105 GSQYDYFKRWLGQGLLISDGDKWRFHRKIITPTFHFSILQQFLTVFDTVGDNFVRKLQQH 164 Query: 180 --ASNFDCHDYMSECTVEILLETAMGVSKST---QDQSGFEYAMAVMKMCDILHLRHTKI 234 +++ + + +S CT++I+ ETAMGV + +D EY + MC I+ R Sbjct: 165 VGSTSVEISNLISLCTLDIICETAMGVKMNALDMKDSENMEYIKGIRIMCKIIVDRMFS- 223 Query: 235 WLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272 +L P + + T + + L +++G VI +K ++ Sbjct: 224 FLHP-IFYPLTLNYYREKRALKMVNGYVDNVISQKIQQ 260 >UniRef50_Q9VXY0 Cluster: Probable cytochrome P450 4s3; n=5; Acalyptratae|Rep: Probable cytochrome P450 4s3 - Drosophila melanogaster (Fruit fly) Length = 495 Score = 186 bits (452), Expect = 2e-45 Identities = 96/232 (41%), Positives = 146/232 (62%), Gaps = 15/232 (6%) Query: 321 GQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 G K+RLAFLD LLL + G +SD +I+E+VDT MFEGHDTT++ +F LS++ + D+ Sbjct: 270 GAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDV 329 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q + EE ++ G ++ M YLE + ETLR+YP VP +R+V +++ + Sbjct: 330 QQRAFEEASELEG--------REKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEV--- 378 Query: 440 GK-KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 GK +P G ++ Y LHR P +P+P +FDPD FL H +AF FSAGPR+C+ Sbjct: 379 GKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNEK-QMHPFAFAAFSAGPRNCI 437 Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 G+K+AML+LK L+ +LR++R + D K+ K A+++ K G ++R+ PR Sbjct: 438 GQKFAMLELKTSLAMLLRSYRFLPD-KDHQPKPLAELVTKSGNGIRLRILPR 488 Score = 145 bits (351), Expect = 3e-33 Identities = 65/190 (34%), Positives = 107/190 (56%), Gaps = 2/190 (1%) Query: 85 HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144 H V +IW G L+V DP D++ +L ++ + K+ Y +PWLG GLL + G+ W Sbjct: 63 HGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESWHR 122 Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS--NFDCHDYMSECTVEILLETAM 202 RKL+ P FH +L F + N R +V +L+ +A+ +FD + Y++ ++ + ETAM Sbjct: 123 RRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAM 182 Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262 G+ K Q QS EY AV +C ++H + W R ++ FK T K + L ++H T Sbjct: 183 GIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDET 242 Query: 263 KKVIKRKKEE 272 +VI+ ++E+ Sbjct: 243 NRVIRLRREQ 252 >UniRef50_UPI0000D9991B Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily A, polypeptide 11 isoform 1; n=3; Catarrhini|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily A, polypeptide 11 isoform 1 - Macaca mulatta Length = 487 Score = 184 bits (448), Expect = 5e-45 Identities = 91/228 (39%), Positives = 142/228 (62%), Gaps = 6/228 (2%) Query: 322 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 +KK L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Q Sbjct: 253 RKKHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 312 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 ++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I+R+++ +T P +G Sbjct: 313 ERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGISRELSTPVTFP-DG 370 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 + +P G T++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+C+G+ Sbjct: 371 RSLPKGITVMLSIYGLHHNPKVWPNPEVFDPSRFAP--GSAQHSHAFLPFSGGSRNCIGK 428 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548 ++AM +LKV + L F ++ D + A ++LK G +RL+ Sbjct: 429 QFAMNELKVATALTLLRFELLPDPTRIPIPM-ARLVLKSKNGIHLRLR 475 Score = 79.4 bits (187), Expect = 2e-13 Identities = 54/179 (30%), Positives = 91/179 (50%), Gaps = 9/179 (5%) Query: 87 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 145 S +W+ G + V L+DP ++VIL + + YRF PW+G GLL+ GQ W H Sbjct: 84 SACPLWLWGGKARVQLHDPDYMKVILGRSDPKSQ-DPYRFLAPWIGYGLLLLNGQTWFQH 142 Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAM 202 R+++ P FH ++LK+++ L + R ++DK +K + S + ++S T++ +++ A Sbjct: 143 RRMLTPAFHYDILKAYVALMADSVRVMLDKWEKLLGQDSPLEVFQHVSLMTLDTIMKCAF 202 Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTK--IWLRPDLLFKFTDYAK-NQTKLLDII 258 S Q S + C + H +HT I LR L K + K + K LD + Sbjct: 203 SHQGSIQVDSLTSTGRWTHRACQLAH-QHTDQVIQLRKAQLQKEGELEKVKRKKHLDFL 260 >UniRef50_A1BPS5 Cluster: CYP4BJ1; n=1; Ips paraconfusus|Rep: CYP4BJ1 - Ips paraconfusus Length = 464 Score = 184 bits (448), Expect = 5e-45 Identities = 86/181 (47%), Positives = 124/181 (68%), Gaps = 3/181 (1%) Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 +KKRLAFLDLLL+ ++DE+I+E+VDT MFEGHDT ++ FF+ M +Q+ Sbjct: 285 EKKRLAFLDLLLDLQYETGRLNDEDIREEVDTFMFEGHDTVSSSMGFFVFSMSQRLHLQE 344 Query: 382 KVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 KV EE+ +IFG D +R VT +D +MKYLE+C+ E +RL P VPII R ++++ + G Sbjct: 345 KVYEEMLEIFGNDEERDVTSEDISQMKYLEQCIREVMRLLPTVPIIGRIISEDTNI--GG 402 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +P TT +IA + + R Y NP+ FDPD+F PER R+ +A++PFSAGPR+C+G+ Sbjct: 403 YMVPKNTTAMIAPFAVQRDKRFYHNPDAFDPDHFTPERVKQRNPFAYIPFSAGPRNCIGQ 462 Query: 501 K 501 K Sbjct: 463 K 463 Score = 117 bits (282), Expect = 7e-25 Identities = 49/131 (37%), Positives = 81/131 (61%), Gaps = 3/131 (2%) Query: 82 DYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQK 141 D D ++++WIGP+ LVF+Y P +VIL S I K EY + WLG GLL STG+K Sbjct: 75 DIDSSGIMRVWIGPKPLVFIYKPETAKVILESQTLITKPGEYGILERWLGTGLLTSTGEK 134 Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILL 198 W + RK++ PTFH ++L +F+ +FN + +++ L + A++ FD + + ++++ Sbjct: 135 WHTRRKMLTPTFHFSILNNFMKVFNRQANTLIENLDRHAADGYPFDFYKVIKALALDVIC 194 Query: 199 ETAMGVSKSTQ 209 E AMG++ Q Sbjct: 195 EAAMGMNIGAQ 205 >UniRef50_A6Y7S1 Cluster: Female neotenic-specific protein 4; n=1; Cryptotermes secundus|Rep: Female neotenic-specific protein 4 - Cryptotermes secundus Length = 271 Score = 184 bits (447), Expect = 7e-45 Identities = 82/199 (41%), Positives = 128/199 (64%), Gaps = 2/199 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G++ R+ LD+L+E S++ +++E++ ++ ++TTA SF M+ HQD+Q Sbjct: 65 GRRARIPILDMLIELSRNDKDYGRLDVREEIAAMLIVSYETTAVALSFACWMLSQHQDVQ 124 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 +KV+ E +IFGDSDRP T++D EMKYLE + ET+RLYP +P+ R++ ++ + Sbjct: 125 EKVLMEQKEIFGDSDRPATYRDIQEMKYLEMVIRETIRLYPSLPVFGRKLQRDFDV--GD 182 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 IPAG ++ Y++HR P +P+P KF+PD FLP+ R Y ++ FSAGPR+CVG Sbjct: 183 FVIPAGANVMFLAYQIHRNPKYFPDPEKFNPDRFLPDNVMRRSPYCYLAFSAGPRNCVGI 242 Query: 501 KYAMLKLKVILSTILRNFR 519 KY M +K LS ++R FR Sbjct: 243 KYGMQAIKGTLSAMIRKFR 261 >UniRef50_A1BPS4 Cluster: CYP4BH1; n=1; Ips paraconfusus|Rep: CYP4BH1 - Ips paraconfusus Length = 499 Score = 183 bits (446), Expect = 1e-44 Identities = 88/230 (38%), Positives = 142/230 (61%), Gaps = 4/230 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G+K+++AFLDLLL ++ G + EEI+ +VDT MF GHDTT++ S ++ IQ Sbjct: 272 GRKRKMAFLDLLLSTNIDGRPPTQEEIRCEVDTFMFAGHDTTSSAMSSAFYVLAKKTQIQ 331 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 V +EL +FG D +T + E+KYLE + E LRLYPP +I+R +++ ++ Sbjct: 332 KMVRDELQGVFGKDGSTQITHKSLQELKYLELFIKEVLRLYPPATVISRVTEEDVQYKNH 391 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 IP T + + Y +R PD + N +F P+ FL + S + +A++PFSAGPR+C+G Sbjct: 392 --TIPKNTLIEMLIYSANRDPDYHENAEEFKPERFL-DTSGKKRPFAYIPFSAGPRNCIG 448 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549 +K+AML++K I+S +L NF V+ + E + + +++LK G V+L+P Sbjct: 449 QKFAMLEMKTIISKVLMNFEVLPSIPEREMVMTTEVVLKAKNGVHVQLKP 498 Score = 149 bits (361), Expect = 2e-34 Identities = 64/169 (37%), Positives = 109/169 (64%), Gaps = 3/169 (1%) Query: 107 VEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFN 166 ++++LSS+ + K +YR PWLG GLL S G +W+SHRK+I P FH ++L+ F+D+FN Sbjct: 90 LDLVLSSNKILTKGGDYRTTAPWLGQGLLTSNGLQWKSHRKMITPAFHFSILEQFVDIFN 149 Query: 167 ANSRAVVDKLKKEA---SNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 223 + +V+KL+++A ++ D + Y++ C ++I+ ETAMGV+ ++Q+ EY AV M Sbjct: 150 SQGDTLVNKLQRDALEKTSIDIYQYVTACALDIICETAMGVNLNSQENHDLEYVQAVKDM 209 Query: 224 CDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272 C I+ R +W D L+ + K Q ++L+I+H T VI ++++E Sbjct: 210 CRIIMDRTFSLWKSFDCLYNLSKLGKKQEQVLEILHNFTNSVINKRRKE 258 >UniRef50_Q16TD6 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 519 Score = 183 bits (445), Expect = 1e-44 Identities = 133/471 (28%), Positives = 219/471 (46%), Gaps = 39/471 (8%) Query: 86 ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST-GQKWRS 144 + + K+ GP ++ + P ++ ++ DK Y + LG GL+ G+ WR Sbjct: 69 DRLAKLRFGPIPVLLVNHPELIQQLMIRPELYDKPFFYEYMG--LGKGLITEQRGEIWRR 126 Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETA 201 RKL+ P F +L F+ + ++ +R +V L + + FD ++CT+E++ T Sbjct: 127 SRKLLNPAFSTRILNEFVPIMDSRARKMVKSLAVLADDKTEFDILPITAQCTLEMVFSTT 186 Query: 202 MGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261 MG K + EY + + + R I +++FT + D +G Sbjct: 187 MGC-KMEERPGEREYVRCLEGLMTCIGERILNIDRYLGPVYRFTKAYQVDKVCRDTCNGF 245 Query: 262 TKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXG 321 T+K+I+ +K E A N+N S ++ G Sbjct: 246 TEKIIQERKREMA------NINNNIIDERMSAAEIDD----------------------G 277 Query: 322 QKKRLAFLDLLLESSQ-SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 + K + FLD +L + G D+E+ + + +I+ G++T+ S+ + + IQ Sbjct: 278 RVKSMNFLDQILTIQRPDGTNFVDDEVSDHLYSIVGAGNETSTLTISYTCLFLAMDHQIQ 337 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 KV E+ Q+F VT + ++ Y E L ETLRL P VP AR + I L +G Sbjct: 338 AKVCSEIKQVFPSHHTEVTPEALKQLIYTEMALKETLRLCPAVPFAARSNVKPIEL--DG 395 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPN-PNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 IP + LHRR D + + P +FDP+ F PE S NRH YA++PFS G R+C+G Sbjct: 396 IHIPQRQIFCFNFFALHRRKDFWGDEPEQFDPNRFSPENSRNRHPYAYLPFSGGFRNCIG 455 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +YA+ LK++L IL+NF + + LK D + + I +K VRL R Sbjct: 456 GRYAINSLKIMLLRILQNFHMDTSLKREDMRFRWAITMKLVGPHAVRLTKR 506 >UniRef50_P13584 Cluster: Cytochrome P450 4B1; n=32; Euteleostomi|Rep: Cytochrome P450 4B1 - Homo sapiens (Human) Length = 511 Score = 182 bits (444), Expect = 2e-44 Identities = 88/228 (38%), Positives = 143/228 (62%), Gaps = 4/228 (1%) Query: 323 KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Q Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 339 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T +G+ Sbjct: 340 RCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV-DGR 397 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+G++ Sbjct: 398 SLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQ 457 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549 +AM ++KV+ + L F D K+ ++L+ GF + L+P Sbjct: 458 FAMSEMKVVTAMCLLRFEFSLDPSRLPIKM-PQLVLRSKNGFHLHLKP 504 Score = 83.8 bits (198), Expect = 1e-14 Identities = 48/185 (25%), Positives = 88/185 (47%), Gaps = 7/185 (3%) Query: 91 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 148 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 205 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200 Query: 206 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKV 265 + Y +AV + ++ R D ++ T + + + + H T +V Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQV 260 Query: 266 IKRKK 270 I+ +K Sbjct: 261 IRERK 265 >UniRef50_UPI00015B61D7 Cluster: PREDICTED: similar to Cytochrome P450, partial; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to Cytochrome P450, partial - Nasonia vitripennis Length = 342 Score = 180 bits (439), Expect = 7e-44 Identities = 88/201 (43%), Positives = 131/201 (65%), Gaps = 3/201 (1%) Query: 321 GQKKRLAFLDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 G++K FLD L++ S++ +S EEI+EQVDT MF GHDTT S+ L +G ++ Sbjct: 119 GKRKPKVFLDRLMDLSEADENPLSLEEIREQVDTFMFGGHDTTGITISWVLFSLGNAPEV 178 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q KV EELD + G ++P T + ++KYL+R + ETLR+YP P++ R ++ + + Sbjct: 179 QRKVHEELDNVIGIGNQPATKEQLSQLKYLDRVIKETLRIYPSAPMVGRILDHNTVI--D 236 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G IP G + + LHR P+++ P+KF+PD FLPE S RH YA+VPFSAGPR+C+G Sbjct: 237 GHIIPKGVVVNLQILHLHRDPEIWDAPDKFNPDRFLPESSNGRHPYAYVPFSAGPRNCIG 296 Query: 500 RKYAMLKLKVILSTILRNFRV 520 +K+A L LK+ L+ I+ + V Sbjct: 297 QKFAGLVLKIALTAIMIKWEV 317 Score = 61.3 bits (142), Expect = 7e-08 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 9/111 (8%) Query: 108 EVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSF------ 161 +VIL S K+ Y FF WLGNGLL S+G W +R+L+ P FH ++L F Sbjct: 3 QVILKSQTLTRKSNIYEFFAYWLGNGLLTSSGDVWHRNRRLMTPAFHFSMLDQFSEIITE 62 Query: 162 -IDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVSKSTQDQ 211 ++LFN + VDK + N + T++ + MGV + Q Sbjct: 63 KVELFNNCIKMEVDKNPEAPINI--FPMAIKFTLDTTCKPVMGVDMAYNPQ 111 >UniRef50_Q02928 Cluster: Cytochrome P450 4A11 precursor; n=114; Tetrapoda|Rep: Cytochrome P450 4A11 precursor - Homo sapiens (Human) Length = 519 Score = 180 bits (437), Expect = 1e-43 Identities = 89/228 (39%), Positives = 140/228 (61%), Gaps = 6/228 (2%) Query: 322 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Q Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 ++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T P +G Sbjct: 345 ERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-DG 402 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 + +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+C+G+ Sbjct: 403 RSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSRNCIGK 460 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548 ++AM +LKV + L F ++ D + A ++LK G +RL+ Sbjct: 461 QFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRLR 507 Score = 87.0 bits (206), Expect = 1e-15 Identities = 51/186 (27%), Positives = 95/186 (51%), Gaps = 6/186 (3%) Query: 92 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 150 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 151 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 207 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 208 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVI 266 Q D++ Y A+ + +++ R + + D ++ T + + + H T +VI Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI 267 Query: 267 KRKKEE 272 + +K + Sbjct: 268 QLRKAQ 273 >UniRef50_UPI00015B5E04 Cluster: PREDICTED: similar to CG8302-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG8302-PA - Nasonia vitripennis Length = 508 Score = 178 bits (433), Expect = 4e-43 Identities = 85/230 (36%), Positives = 144/230 (62%), Gaps = 5/230 (2%) Query: 324 KRLAFLDLLLESSQSGVA-ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 K+ + L+ ++E+S+ SDE+I + T M G D+ ++ L ++ H D QDK Sbjct: 277 KKTSLLEYMMETSERNPEWFSDEDIINECCTFMLAGQDSVGTATAMTLFLLANHPDWQDK 336 Query: 383 VIEELDQIF--GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 EELD+IF G+++RP T QD M++LE C+ E LRLYP VPI AR++ +++ + + Sbjct: 337 CREELDEIFAEGETNRPPTMQDLRAMRWLECCIKEALRLYPSVPIFARKLGEDVKVGKH- 395 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 IP+G ++I Y HR P +P+P+ F P+ F PE S RH YA++PFSAGPR+C+G Sbjct: 396 -VIPSGCGVIILPYSTHRLPHHFPDPHSFRPERFSPENSEKRHPYAYLPFSAGPRNCIGN 454 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 K+A+L++K ++S ILR +R+ +++ + + + ++ + G +++ R Sbjct: 455 KFAILEMKAVISAILRRYRLGGVEGKTEVRPKFRLTVRASGGLWLKISQR 504 Score = 93.9 bits (223), Expect = 1e-17 Identities = 61/223 (27%), Positives = 108/223 (48%), Gaps = 8/223 (3%) Query: 76 IVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLL 135 ++ +A D+ V + W+ V L +P D++ +L S + K YR +LG GL+ Sbjct: 68 VMSHTAYKDYGPVARFWVTLIPYVILLEPDDIQAVLGSAKHTSKIFVYRLLDNFLGKGLI 127 Query: 136 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-EASNFDCHDYMSECTV 194 S WR+HR+L+ P FHL+VL+ F+ F + + D+L + + D ++++ Sbjct: 128 TSDVDTWRTHRRLLQPAFHLHVLQKFVGSFAERADRLADRLARYDNQQLDITKFVNDAVY 187 Query: 195 EILLETAMGVS-KSTQDQSGFEYA--MAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQ 251 EIL ET +GV+ ST ++ G + K ++ R + WL D ++K T + + Sbjct: 188 EILNETVLGVNVASTANEDGVVDLDDLPFRKGQVLMTHRLIRPWLIFDWIYKLTSTGQQE 247 Query: 252 TKLLDIIHGLTKKVIKRK----KEEFASGKKPSNLNETATTSE 290 K + ++I+ K ++ + KK S L TSE Sbjct: 248 KKQSQDLSAACHRIIQEKRRLQRDSSSLTKKTSLLEYMMETSE 290 >UniRef50_Q9N525 Cluster: Cytochrome p450 family protein 29A3; n=6; Caenorhabditis|Rep: Cytochrome p450 family protein 29A3 - Caenorhabditis elegans Length = 503 Score = 177 bits (432), Expect = 5e-43 Identities = 91/229 (39%), Positives = 139/229 (60%), Gaps = 4/229 (1%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 K+ + FLD+LL + +S V +S E+++++VDT MF GHDTT S+ + H DIQ Sbjct: 277 KRNMNFLDILLSNEESSV-LSPEDLRQEVDTFMFAGHDTTTTSVSWVCWNLAHHPDIQQN 335 Query: 383 VIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 V EE+ +FG D + VT + +++Y ER L E+ R+ P VP + RQ+ ++ + G Sbjct: 336 VYEEIVSVFGEDPNEDVTTEGIKKLEYTERMLKESKRICPTVPAVLRQLISDMEI--GGV 393 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 IPAG + IA +H+ ++Y NP+ FDPD FLPE +A RH Y F+PFSAG R+C+G+K Sbjct: 394 LIPAGANVAIAPMAIHKNANIYQNPDIFDPDRFLPEETAKRHAYDFIPFSAGLRNCIGQK 453 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +A L KV++ +L+NF++ K + + K + G VRL R Sbjct: 454 FAQLNEKVMVIHLLKNFKIEPMGGYYSTKQVFEPVGKPSNGIPVRLVRR 502 Score = 104 bits (250), Expect = 5e-21 Identities = 62/211 (29%), Positives = 101/211 (47%), Gaps = 9/211 (4%) Query: 71 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 130 D+F V+K +S+++ I V+ D + V IL S +DK Y FF WL Sbjct: 65 DLFSEAVEKG-----QSLIRHRILGTFYVWPLDGKTVSKILESTTELDKGGPYEFFNDWL 119 Query: 131 GNGLLIST-GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV---DKLKKEASNFDCH 186 G G L+ G++WRSHRK++ PTFH L+ + ++FN SR VV DK K D Sbjct: 120 GGGTLLEGYGERWRSHRKMLTPTFHFAKLEGYFEVFNTESRVVVDCLDKFAKSGETVDLF 179 Query: 187 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 246 + CT++ + +TAMG Q Q+ Y A+ + + L + ++ Sbjct: 180 PFFKRCTLDTICKTAMGAKVDAQLQNSHPYITAIEQALQLGVLYAMNPHHQIPAIYWALG 239 Query: 247 YAKNQTKLLDIIHGLTKKVIKRKKEEFASGK 277 + K + + +I+ T+ VI ++ SG+ Sbjct: 240 HQKKKDEYFNIMKTFTRNVIAERRTARESGE 270 >UniRef50_UPI00015B4DC8 Cluster: PREDICTED: similar to corpora allata cytochrome P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to corpora allata cytochrome P450 - Nasonia vitripennis Length = 513 Score = 177 bits (431), Expect = 6e-43 Identities = 84/223 (37%), Positives = 139/223 (62%), Gaps = 4/223 (1%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 LDLLL+ Q+G ++D +++++V+T MF GHDT S+ L +G H + Q+++I E++ Sbjct: 293 LDLLLQMVQNGEKLTDNDLRDEVNTFMFAGHDTVGMSVSWILYSLGRHPEYQERIIREVE 352 Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448 + ++ + F+ + +L C+ E RLYP P+IARQ+N ITL ++ IP GTT Sbjct: 353 DLLA-AEGELGFESYNRLHWLGACVKEAWRLYPVTPLIARQINSPITLQNHD--IPVGTT 409 Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508 ++I +Y LHR P +P P +F P+ FLP S + AF+PFSAG R+C+G K+A +++K Sbjct: 410 VLINSYLLHRDPRYFPEPERFKPERFLPGASKPPSF-AFIPFSAGSRNCIGYKFATIEVK 468 Query: 509 VILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 V + +LR +R + L+E L + ++L G Q+ + PR+ Sbjct: 469 VTVLALLRAYRFRAILREDQLHLLSQVVLDNVGGIQLSITPRQ 511 Score = 126 bits (303), Expect = 2e-27 Identities = 70/230 (30%), Positives = 115/230 (50%), Gaps = 8/230 (3%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120 N ++ + D F + + + ++ + +W+G R VF+Y V +LSS +IDK+ Sbjct: 57 NFVQLLCNLEDFFAKLTEWAQEFG--DIYLLWVGLRPFVFVYRMEAVGTLLSSRQHIDKS 114 Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180 EY + KPWLG+GL+ STG++W + RKL+ PTFH +LK + + + V+ L+ E Sbjct: 115 LEYEYLKPWLGSGLITSTGERWLARRKLLTPTFHSELLKGYFRVTLREADTFVECLRSEI 174 Query: 181 S--NFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRP 238 FD + ++ + AMG + Q EY AV ++ I R T I L+P Sbjct: 175 GKLEFDIVPFAKRAALDTICVCAMGHQLNAQVNRRNEYVQAVQRLTAISQRRFTSILLKP 234 Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGK----KPSNLNE 284 +LLFK + + + L +I VI K ++ + + SN NE Sbjct: 235 ELLFKVSTLGREHDRALRVIEDFVNGVITDTKRDWLGSRLRRARASNNNE 284 >UniRef50_UPI0000D56470 Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=5; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 495 Score = 177 bits (431), Expect = 6e-43 Identities = 87/227 (38%), Positives = 142/227 (62%), Gaps = 4/227 (1%) Query: 324 KRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383 K+ FL+ LL +S++ I + I E++ TI+ G +TTA ++GI+ +IQ+KV Sbjct: 267 KKKRFLNHLLTTSETNPQIDELAILEEIQTILVTGSETTAITIGMVFIILGIYPEIQEKV 326 Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443 EL+ I G DR +T +D ++YLER + ETLR+ P VP+I R V Q++ L + K I Sbjct: 327 RSELELILGPDDREITLEDINNLEYLERVIKETLRVLPIVPLITRTVEQDVKLGT--KTI 384 Query: 444 PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYA 503 P+G+ +++ + ++ + + P KFDPD FLPE +ANR +F+PFS GPR+C+G KY Sbjct: 385 PSGSFVLVPIASIGKKAEFWAEPKKFDPDRFLPENNANRPRCSFIPFSYGPRNCIGFKYG 444 Query: 504 MLKLKVILSTILR--NFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548 M+ LKV+L+T++R F+ + D +L ++ K GF+V+++ Sbjct: 445 MMSLKVLLATVIRKFTFKPSQYRRIEDVRLIYGMVAKPKHGFKVKIE 491 Score = 128 bits (309), Expect = 4e-28 Identities = 87/281 (30%), Positives = 133/281 (47%), Gaps = 9/281 (3%) Query: 26 VPAVILWYAY-WRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYD 84 + A+ L++ + RR LY K++ +A F+GG ++ +V+ Sbjct: 15 ISALALFFLVKYNWKRRWLYYHGSKIDGPFGWPIIGSAHYFIGGQKVFYQKMVKVFET-- 72 Query: 85 HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144 SV K W+G LLV P DVE++L+++ K + Y F NGLLI+ WR Sbjct: 73 QPSVFKFWLGKDLLVVTSKPEDVEIVLNNNSCFGKPKFYDFAFKLFRNGLLIAPASIWRD 132 Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGV 204 R++I PTF+ +L SFI++F + +V L++ S D + CT +I ET V Sbjct: 133 RRRVINPTFNPKILNSFIEIFGKHGNKLVKVLEESCSESDIFLKLFRCTFDIACETLADV 192 Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264 S + +Y V++M DIL +R IWL PD L+K + Y K K + K+ Sbjct: 193 D-SELIKGQDKYLQTVIRMEDILAIRSFSIWLHPDFLWKRSFYGKEMEKASAEVFAFVKQ 251 Query: 265 VIKRKKEEFASG---KKPSNLNETATTSE--PSTGKLTSVE 300 ++ KK KK LN TTSE P +L +E Sbjct: 252 ILALKKASVTDDENYKKKRFLNHLLTTSETNPQIDELAILE 292 >UniRef50_UPI0000F2BA18 Cluster: PREDICTED: similar to Cytochrome P450 4A2 precursor (CYPIVA2) (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2); n=1; Monodelphis domestica|Rep: PREDICTED: similar to Cytochrome P450 4A2 precursor (CYPIVA2) (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) - Monodelphis domestica Length = 519 Score = 177 bits (430), Expect = 8e-43 Identities = 86/229 (37%), Positives = 140/229 (61%), Gaps = 4/229 (1%) Query: 322 QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 +KK L FLD+L ++ + G ++EE++ +V+T F G DT A G S+ L + ++ + Q Sbjct: 292 KKKYLNFLDILFQAKDEDGGGFTNEELENEVNTFRFAGQDTVAVGFSWTLYCLAMNPEYQ 351 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 K EE+ I D + +T+ +M Y C+ E+ R+Y P+P +AR +NQ IT P +G Sbjct: 352 KKCREEIQGILKDGES-ITWDHLTQMTYSTMCIKESFRMYSPIPKVARTLNQPITFP-DG 409 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 + +P+ TT+ I + LH P ++ NP FDP+ F PE + RH YAF+PFSAG R+C+G+ Sbjct: 410 QTLPSDTTVTINIWALHYNPAIWENPKVFDPERFTPENTKKRHPYAFLPFSAGLRNCIGQ 469 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549 ++AM +KV L+ L F ++ DL++ + + I+L+ GF L+P Sbjct: 470 QFAMNLIKVSLALTLLRFELLPDLEKPPIPI-SQIVLRSTSGFHFYLKP 517 Score = 70.5 bits (165), Expect = 1e-10 Identities = 37/126 (29%), Positives = 66/126 (52%), Gaps = 4/126 (3%) Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVD---KLKKEASNFDCHD 187 G GLL G+KW HR+L+ P FH N+LK +I + ++D KL+ + S+ D D Sbjct: 136 GKGLLSLEGEKWHYHRRLLTPAFHFNILKDYIYIMRNTVSLMLDKWEKLRTKDSSIDVFD 195 Query: 188 YMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFT-D 246 ++S +++ L+ G+ +++S F Y + K+ ++ R D ++K T D Sbjct: 196 FISYMSLDTSLKATFGLQDFNKEESLFSYFQNMNKLLYLVRKRMETFLYYSDFIYKLTSD 255 Query: 247 YAKNQT 252 + + QT Sbjct: 256 HYEFQT 261 >UniRef50_UPI00015B5196 Cluster: PREDICTED: similar to cytochrome P450 CYP4C39; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP4C39 - Nasonia vitripennis Length = 507 Score = 176 bits (428), Expect = 1e-42 Identities = 87/234 (37%), Positives = 137/234 (58%), Gaps = 4/234 (1%) Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 +K + L LL + +++EE+++++ TI DT A SSF + M+GIH D+Q Sbjct: 276 EKSKTCILHRLLTVNSVTNELTEEELRDEIYTIYIASQDTLAVTSSFAVLMLGIHGDVQK 335 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 K E+D++ G D V + ++KYLE + ETLRL+P P++ RQ+N E+ L ++ Sbjct: 336 KARSEVDEVIGVGD--VNIESLSKLKYLEMVIKETLRLFPIAPLMVRQLNGELKLDNS-- 391 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 +P +VIA Y HR + NP F P+ F + + RH Y F+PFS GP C+G+K Sbjct: 392 ILPKDCQVVIAPYATHRSSKFWENPENFLPERFAIKETVKRHPYTFIPFSGGPMGCIGQK 451 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRMAK 555 YA+ LK+IL+ IL+ + V SD+ D KL+ DI ++ G+++ LQ R + K Sbjct: 452 YALTALKMILANILQKYVVESDVTLRDIKLKTDISIRSMNGYKISLQARTNITK 505 Score = 158 bits (383), Expect = 4e-37 Identities = 84/268 (31%), Positives = 140/268 (52%), Gaps = 5/268 (1%) Query: 38 MSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRL 97 ++++R+ ELA KL NAL+F + IV A Y + +++W+GP L Sbjct: 33 VNKKRIIELAIKLPGPRAYPIIGNALKFACEPDQLLERIVDVIAPYADVTPMRLWMGPML 92 Query: 98 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNV 157 V + +PRD+EV+L+S K Y+F P++GNGL+ +G+ W++HRK+I+ + Sbjct: 93 YVIITEPRDIEVVLNSQQATSKGSAYKFLYPFIGNGLISGSGKSWKAHRKIISHILNQRT 152 Query: 158 LKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAMG---VSKSTQDQS 212 L SFI+ F+ S+ V KL+ A+ FD + CT++++ ET MG ++ Sbjct: 153 LDSFIETFDRRSKEFVKKLEPLANGEVFDIFHSLEGCTIDLVCETVMGYTDINALDNPNK 212 Query: 213 GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272 F + A +M I+H R KIWL PD +F+ T NQ + +IH T++ I+ +++ Sbjct: 213 EFVHYTADFRMYKIIHNRMMKIWLYPDWIFRITSNYSNQKRAQTMIHNFTERCIEAGRQD 272 Query: 273 FASGKKPSNLNETATTSEPSTGKLTSVE 300 K + + T T +LT E Sbjct: 273 MLKEKSKTCILHRLLTVNSVTNELTEEE 300 >UniRef50_Q4U3Y4 Cluster: CYP325C2; n=4; Anopheles gambiae|Rep: CYP325C2 - Anopheles gambiae (African malaria mosquito) Length = 264 Score = 175 bits (426), Expect = 3e-42 Identities = 88/229 (38%), Positives = 142/229 (62%), Gaps = 3/229 (1%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 KK L F D LL + +G +D E+ + +++ G+DTTA + + +H IQ++ Sbjct: 37 KKPLIFADQLLAAQHNGNPFTDIEVTHNIYSMIAAGNDTTALQVTHTCLFLAMHPAIQER 96 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 V E+ +F D D+ + +D ++ Y+ER + E+LRL P P IARQ ++I + G Sbjct: 97 VYREVMDVFPDPDQDIEVEDLKKLTYMERVIKESLRLAPSGPNIARQTMKDIEIA--GVH 154 Query: 443 IPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 IP + +V++ + +HRR D++ P+ + FDPD FLPERS R F+PFSAG R+C+G + Sbjct: 155 IPRDSLIVMSIFSMHRRKDIWGPDADLFDPDRFLPERSEGRSTNVFIPFSAGSRNCIGGR 214 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 YAML +KV+LS+ILR R+ SDL+ +D + + D+ LK + V+++ R Sbjct: 215 YAMLSMKVMLSSILRRLRLRSDLQMNDLQFRFDLTLKLESEYFVQVEKR 263 >UniRef50_Q6PW73 Cluster: Cytochrome P450 CYP4AT1; n=1; Capitella capitata|Rep: Cytochrome P450 CYP4AT1 - Capitella capitata Length = 490 Score = 175 bits (425), Expect = 3e-42 Identities = 87/227 (38%), Positives = 143/227 (62%), Gaps = 4/227 (1%) Query: 324 KRLAFLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 + L FLD+LL++ S G ++DEEI+ +VDT MFEGHDTTA+G S+ L + H + QD+ Sbjct: 265 QNLDFLDILLDAKDSDGRGLTDEEIQHEVDTFMFEGHDTTASGLSWCLYNLARHPEYQDR 324 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 +E+ + GD V + D ++ +L C+ E+LRL+P VP I R + + +T P +G+ Sbjct: 325 CRKEVMDVMGDRS-DVEWDDMSKLTFLTMCIKESLRLHPAVPNIGRSLTKPMTFP-DGRT 382 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 +PA T L IA Y H ++ NP ++DP+ F E S +R ++F+PFSAGPR+C+G+ + Sbjct: 383 VPAETDLGIAIYGCHHNSALWENPEQYDPERFNAENSKDRPPHSFIPFSAGPRNCIGQHF 442 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549 AM +++ +L+ L+NF++ D +L ++LK G +++ P Sbjct: 443 AMHEMRSVLAVCLKNFQLRID-DTRILELLPQLVLKAKGGLWLKVTP 488 Score = 82.2 bits (194), Expect = 3e-14 Identities = 49/168 (29%), Positives = 90/168 (53%), Gaps = 6/168 (3%) Query: 93 IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPT 152 IG + + L P + +LS+ D+ YR KPW+G+GLL+S+G+KW +R+L+ P Sbjct: 68 IGLYVCMELSHPSPLSKLLSTAEPKDRIS-YRTIKPWIGDGLLVSSGEKWARNRRLLTPA 126 Query: 153 FHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGVSKST 208 FH +VLK ++ +F++ + + DK +K S D ++S T++ LL+ G + S Sbjct: 127 FHFDVLKPYVGIFSSTANIMADKWRKILSKNDEPLEMFQHVSLMTLDSLLKCIFGQTGSV 186 Query: 209 QDQS-GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLL 255 Q++ Y +V ++ +++ R D ++ FT A + +L Sbjct: 187 QNEGRDGSYIRSVYQLTELVMKRFQFFPYLIDWIYYFTPSALQVSPML 234 >UniRef50_Q8K4D6 Cluster: Cytochrome P450 4X1; n=15; Eutheria|Rep: Cytochrome P450 4X1 - Rattus norvegicus (Rat) Length = 507 Score = 172 bits (418), Expect = 2e-41 Identities = 87/223 (39%), Positives = 141/223 (63%), Gaps = 6/223 (2%) Query: 328 FLDLLLESSQSG--VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIE 385 FLD++L S+Q+G A SD +++ +V+T M+ GHD +AA S+ L + ++ + QD+ Sbjct: 284 FLDIVL-SAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRT 342 Query: 386 ELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445 E+ I GD +T++ E+ Y C+ ETLRL PP+P I+R++++ +TLP +G +PA Sbjct: 343 EIRSILGDGSS-ITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLTLP-DGHSLPA 400 Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505 G T+V++ + LH P V+ +P FDP F E S RH AF+PFS+GPR+C+G+++AML Sbjct: 401 GMTVVLSIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQQFAML 460 Query: 506 KLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548 +LKV ++ L FRV +DL + +L+ G + L+ Sbjct: 461 ELKVAIALTLLRFRVAADLTRPP-AFSSHTVLRPKHGIYLHLK 502 Score = 90.6 bits (215), Expect = 9e-17 Identities = 55/205 (26%), Positives = 105/205 (51%), Gaps = 14/205 (6%) Query: 92 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 148 W+GP + ++YDP ++ LS D +Y + P+LG GLL G +W HR L Sbjct: 83 WVGPFQAFFYIYDPDYAKIFLSR---TDPKTQYLHQLMTPFLGRGLLNLDGPRWFQHRCL 139 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMSECTVEILLETAMGV 204 + P FH ++LK +D+ + ++DK +K + + + ++++ T++I+++ A G Sbjct: 140 LTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQETTIEVFEHINLMTLDIIMKCAFGQ 199 Query: 205 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTK 263 + Q +E Y A ++ +I+ R W D++FK + +L +IH T+ Sbjct: 200 ETNCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQCTE 259 Query: 264 KVIKRKKEEFASGKKPSNLNETATT 288 K+I+ +K+ K N ++T T+ Sbjct: 260 KIIQDRKKTL---KDQVNQDDTQTS 281 >UniRef50_Q17DZ0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 504 Score = 171 bits (417), Expect = 3e-41 Identities = 89/228 (39%), Positives = 131/228 (57%), Gaps = 3/228 (1%) Query: 324 KRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383 K AFL+ LL G + +D+EI T++ G++TTA + M+ +H DIQ++V Sbjct: 266 KSKAFLERLLTIQHKGRSFTDDEIINHAYTMLVAGYETTALQLTNVCMMLAMHPDIQERV 325 Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443 E+ IF D + + ++ YL+ + ET+RLYP VP+IARQ N + L I Sbjct: 326 ASEIKTIFPSLDMEILPEALKDLPYLDMTINETMRLYPVVPLIARQSNSSLELDK--VNI 383 Query: 444 PAGTTLVIATYKLHRRPDVYPNPN-KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 P GT ++ LHRR DV+ F+PDNFLPE+ RH YAF+P SAGPR C+G +Y Sbjct: 384 PTGTNFIVHIGALHRRKDVWGEEVLDFNPDNFLPEKVERRHPYAFIPLSAGPRVCIGNRY 443 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 AML LKV L +L+ +R+ + L D K + + LK + V+++ R Sbjct: 444 AMLSLKVFLIRLLQRYRLSTKLTRKDLKFKFQVTLKLKIPYTVQMERR 491 Score = 72.1 bits (169), Expect = 3e-11 Identities = 43/126 (34%), Positives = 70/126 (55%), Gaps = 8/126 (6%) Query: 75 NIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGL 134 N K D +H + KIW+GP L+ + P V+ +L+ IDK Y F + LG GL Sbjct: 53 NAYMKVFDKEHR-MSKIWLGPVPLINVQHPELVQKVLNE--CIDKPFAYDFME--LGQGL 107 Query: 135 LIST-GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSE 191 + GQ+WR HRK ++P F+ +L SFI +F + V+ +L+ + +FD +Y S Sbjct: 108 VSERYGQRWREHRKTLSPLFNTKILHSFIPIFERATSDVMKRLEVVCDGRDFDLLEYTSS 167 Query: 192 CTVEIL 197 C+ +++ Sbjct: 168 CSAKMV 173 >UniRef50_Q27606 Cluster: Cytochrome P450 4e2; n=11; Diptera|Rep: Cytochrome P450 4e2 - Drosophila melanogaster (Fruit fly) Length = 526 Score = 170 bits (413), Expect = 1e-40 Identities = 84/206 (40%), Positives = 132/206 (64%), Gaps = 7/206 (3%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 +K++AFLD LL S+ G ++ +E+ E+V T MFEGHDTT +G SF + ++ HQD Q K Sbjct: 273 RKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRK 332 Query: 383 VIEELDQIFGDSD--RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 + +E ++ G+S+ R TFQ+ +MKYL+ + E R+YP VP I R ++ + +G Sbjct: 333 LFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVI--DG 390 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +P GTTL + L V+ +P+KF P+ F E+ + +VPFSAGPR+C+G+ Sbjct: 391 DLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPGP---FEYVPFSAGPRNCIGQ 447 Query: 501 KYAMLKLKVILSTILRNFRVISDLKE 526 K+A+L++K ++S I+RNF V+ L E Sbjct: 448 KFALLEIKTVVSKIIRNFEVLPALDE 473 Score = 127 bits (307), Expect = 7e-28 Identities = 77/271 (28%), Positives = 129/271 (47%), Gaps = 6/271 (2%) Query: 20 LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79 L+ L +P +++ AY +S R + +K N NA + ++I + Sbjct: 5 LYIFLALPLLLV--AYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSW 62 Query: 80 SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139 Y ++ V WIG V + + +E ILSS I K++ Y+ PWLG GLL STG Sbjct: 63 WHQYGKDNFV-FWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTG 121 Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSEC---TVEI 196 KW HRK+I P FH N+L+ F ++ N NS + LK A+ + D+ + T+++ Sbjct: 122 SKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDV 181 Query: 197 LLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLD 256 + +TAMGVS + + A MC +++R R +LL++ ++ L Sbjct: 182 ICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLK 241 Query: 257 IIHGLTKKVIKRKKEEFASGKKPSNLNETAT 287 + T ++I ++ E SG +N + T Sbjct: 242 TLQDFTNEIIAKRIEAHKSGAVSTNAGDEFT 272 >UniRef50_Q16L55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 463 Score = 169 bits (412), Expect = 1e-40 Identities = 132/479 (27%), Positives = 229/479 (47%), Gaps = 43/479 (8%) Query: 28 AVILWYA-YWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSAD-IFRNIVQKSADYDH 85 +V+++ A Y+R SRR+ +N + S + IF V+ + Y Sbjct: 11 SVLVFLAVYYRWSRRKTNAALANMNGPPKYPLIGHLYLLKYTSQEKIFETFVELGSTYS- 69 Query: 86 ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 145 S + I +GP LV +Y P ++ +LSS I + Y FF+ + G+ S WR Sbjct: 70 -SPMGIELGPITLVVVYQPEHLQAVLSSPHCISRPFWYDFFR--VSRGIFSSPAHIWRGQ 126 Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMG 203 RK++ +F +L F+ +FN S + + D ++ ++ + TA G Sbjct: 127 RKVLNHSFGPGILNCFVSIFNEKSEILTKLMTSHVGRGERDFGHEIARAALDTIYSTAFG 186 Query: 204 VSKSTQDQ-SGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262 ++ Q+ G +Y A + ++ R +F +Y++ I+ LT Sbjct: 187 LNFGMQEAPEGSKYLEAQEEFIGLVLKR----------IFSVINYSER-------IYRLT 229 Query: 263 KKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQ 322 K KR++E + + +N A +E + ++ + G Sbjct: 230 KDY-KREQELLSYARTLTNRIMQARNAEQILSGAIGLPSVTTENTDG------------- 275 Query: 323 KKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 KK FLD L E + ++ +S E+I E +DTI+F G+DTTA S L M+ +H D+Q+ Sbjct: 276 KKPQIFLDKLFELAVENKQQLSKEDIPEHLDTIIFAGNDTTATTMSNLLLMLAMHPDVQE 335 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 +V +E+ + D ++PV+ +DT ++ Y E ET+RL+P P+I R +I + S+ Sbjct: 336 RVYQEVMEACPDLEQPVSMEDTAKLTYTEMVCKETMRLFPVGPLIGRIAEVDIKI-SDEH 394 Query: 442 KIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 IPAG+ + Y +HR ++ P +F+PD+FLPE + H YA++PFS G R+C+G Sbjct: 395 VIPAGSEVGCGIYMVHRDRKIWGPRAEEFNPDHFLPENISKIHPYAYLPFSGGIRNCIG 453 >UniRef50_Q170T3 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 497 Score = 169 bits (411), Expect = 2e-40 Identities = 82/203 (40%), Positives = 130/203 (64%), Gaps = 4/203 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G KK+ AFLD+LL +S +G +++ EI+E+VDT MFEGHDTT + F L + H +IQ Sbjct: 295 GAKKKDAFLDMLLRTSINGKPLTNLEIREEVDTFMFEGHDTTTSAVVFTLFNLAKHPEIQ 354 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 KV +E+ + G D + ++ Y E + ETLRL+P VP+I R+ +EIT+ Sbjct: 355 QKVYDEIVSVIGKDPKEKIELSHLHDLSYTEMAIKETLRLFPSVPLIGRRCVEEITI--E 412 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCV 498 GK IPAG +++ Y + R + NP++F P+ F E S + + Y ++PFSAGPR+C+ Sbjct: 413 GKTIPAGANIIVGIYFMGRDTKYFENPSQFIPERFEGEFSVEKFNPYKYIPFSAGPRNCI 472 Query: 499 GRKYAMLKLKVILSTILRNFRVI 521 G+K+A+ ++K ++S +LR++ I Sbjct: 473 GQKFALNEMKSVISKLLRHYEFI 495 Score = 88.2 bits (209), Expect = 5e-16 Identities = 62/210 (29%), Positives = 102/210 (48%), Gaps = 14/210 (6%) Query: 102 YDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSF 161 Y + IL++ DK+ EY + WLG+GLL+S KW + RK I P FH +L+ F Sbjct: 114 YSIHTFQTILTNKHLTDKSGEYDYLSNWLGDGLLLSKRHKWHARRKAITPAFHFKILEQF 173 Query: 162 IDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILL-ETAMGVSKSTQDQSGFEYA 217 +D+F+ N+ +VD L+K A + FD Y+ ++++ E G + ++ + Sbjct: 174 VDVFDRNAAELVDVLEKHADDGKTFDMFPYVLLYALDVICGELGTGCKLKRKHENLDNFR 233 Query: 218 MAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKK------E 271 + + R I R L + Y K + K L ++HG T VI ++ + Sbjct: 234 KCNGNITHVSIKRMFDIIRRTSLFYLTPSYQKLR-KALKVLHGYTDNVIVSRRNQLMISD 292 Query: 272 EFASGKKPSNLNETATTSEPSTGK-LTSVE 300 EF + KK + L+ TS GK LT++E Sbjct: 293 EFGAKKKDAFLDMLLRTS--INGKPLTNLE 320 >UniRef50_Q6NT55 Cluster: Cytochrome P450 4F22; n=127; Deuterostomia|Rep: Cytochrome P450 4F22 - Homo sapiens (Human) Length = 531 Score = 168 bits (408), Expect = 4e-40 Identities = 81/230 (35%), Positives = 140/230 (60%), Gaps = 4/230 (1%) Query: 322 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 Q K L F+D LLL + G +SDE+I+ + DT MFEGHDTT++G S+ L + + + Q Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358 Query: 381 DKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 +K EE+ ++ G + + D ++ + C+ E+LR YPPV +++RQ ++I LP + Sbjct: 359 EKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP-D 417 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G+ IP G +++ Y H P V+P+ ++P F P+ R A+VPFSAGPR+C+G Sbjct: 418 GRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549 + +AM +L+V+++ L FR+ D + + + ++IL+ G ++++P Sbjct: 478 QSFAMAELRVVVALTLLRFRLSVD-RTRKVRRKPELILRTENGLWLKVEP 526 Score = 92.3 bits (219), Expect = 3e-17 Identities = 53/200 (26%), Positives = 107/200 (53%), Gaps = 9/200 (4%) Query: 78 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 134 +K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144 Query: 135 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 190 L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K + A + D +++S Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204 Query: 191 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 250 T++ L + + + Q++ +Y A++++ + R ++ D ++ + + Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRR 263 Query: 251 QTKLLDIIHGLTKKVIKRKK 270 + D++H T +VI+ ++ Sbjct: 264 FRQACDMVHHFTTEVIQERR 283 >UniRef50_Q9V558 Cluster: Cytochrome P450 4p1; n=5; Sophophora|Rep: Cytochrome P450 4p1 - Drosophila melanogaster (Fruit fly) Length = 513 Score = 167 bits (407), Expect = 5e-40 Identities = 85/228 (37%), Positives = 133/228 (58%), Gaps = 2/228 (0%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 KKR A LD L+ + + G+ I I E+VDT+MFEG+DTT+ G F L M ++ D Q+ Sbjct: 287 KKRFAMLDTLIYAEKDGL-IDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQEL 345 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 +E+ + D + ++KYLE + ET RL+P VPI+ R+ QE L +NG Sbjct: 346 CYQEIQEHIDDDLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETEL-ANGLI 404 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 +P G + I + +HR + +P +F P+ FLPE +RH YA+VPFSAG R+C+G+KY Sbjct: 405 LPKGAQITIHVFDIHRNAKYWDSPEEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKY 464 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 AM ++K ++ +L+ F+V+ + I L+ + +V+L R Sbjct: 465 AMQEMKTLMVVLLKQFKVLKAIDPQKIVFHTGITLRTQDKIRVKLVRR 512 Score = 93.5 bits (222), Expect = 1e-17 Identities = 61/215 (28%), Positives = 106/215 (49%), Gaps = 9/215 (4%) Query: 61 NALEFVGGS-ADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDK 119 N L+ G A +F N ++ A S ++ G + + + D E +L+ I K Sbjct: 57 NTLDLYGRDHAGVF-NYSRERAKEMGTSYIEYVFG-KAIYNIIDADSAENVLNHPNLITK 114 Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK-K 178 Y F P+L GLL STG+KW + RK++ PTFH N+L F ++F S+ + + + + Sbjct: 115 GLVYNFLHPFLRTGLLTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQFEGQ 174 Query: 179 EASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYA--MAVMKMCDILHLRHTKIWL 236 + HD + T+ + ETAMGV + G Y + ++ C I L + +W Sbjct: 175 DEVTITLHDVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLW- 233 Query: 237 RPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKE 271 D LF+ AK+ LD++H + ++I ++++ Sbjct: 234 -GDKLFEMF-AAKDFASALDVVHRFSSEIIAKRRD 266 >UniRef50_Q6TGT4 Cluster: Thromboxane A synthase 1; n=6; cellular organisms|Rep: Thromboxane A synthase 1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 546 Score = 167 bits (405), Expect = 9e-40 Identities = 129/507 (25%), Positives = 232/507 (45%), Gaps = 28/507 (5%) Query: 63 LEFVGGSADIFRNIVQKS-ADYDHE--SVVKIWIGPRLLVFLYDPRDVEVILSSHV--YI 117 L F+G +FRN KS AD ++ + +IG R V + DP + ++ + Sbjct: 54 LPFIGNLM-MFRNGFFKSQADLINKYGRICGYYIGRRSTVIIADPDMLRQVMVKEFNKFP 112 Query: 118 DKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK 177 ++ KP + + L++ G++W+ R ++ PTF +K + L N + ++ LK Sbjct: 113 NRMTARGITKP-MSDSLIMLKGEQWKRVRSILTPTFSAAKMKEMVPLINTATETLLRNLK 171 Query: 178 KEA---SNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKI 234 A ++F+ H T++++ A G +Q+ + K R I Sbjct: 172 SHAESENSFNIHKCFGCFTMDVIASVAFGTQVDSQNNPDDPFVHQASKFFAFSFFRPIMI 231 Query: 235 WLR--PDLLFKFTDYAKNQTK--LLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSE 290 + P LL N+++ + +K+IK++ + ++ L Sbjct: 232 FFMAFPFLLRPLAGLLPNKSRDEMNSFFTQCIQKMIKQRDDLSPEQRRKDFLQLMLDVR- 290 Query: 291 PSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQ 350 + K SVE + + + + SQ ++++EI Q Sbjct: 291 -TNNKFLSVEHFDVVNDADEEAYDGHENSPANEST--------KRSQQKRMMTEDEIVGQ 341 Query: 351 VDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLE 410 + G++T++ +F ++ +H + Q K+ EE+D+ F + V + + E+KYL+ Sbjct: 342 SFIFLVAGYETSSNTLAFTCYLLAVHPECQKKLQEEVDEFFSRHEM-VDYANVQELKYLD 400 Query: 411 RCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFD 470 + E+LRLYPP +AR V ++ L NG+ +P G +L I T LH P+ + P KF Sbjct: 401 MVICESLRLYPPAFRVARDVEEDTVL--NGQFLPKGASLEIPTGFLHYDPEHWTEPTKFI 458 Query: 471 PDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS-DLKESDF 529 P+ F PE A RH + ++PF AGPRSCVG + A L++KV L I R F V++ + E Sbjct: 459 PERFTPEAKARRHPFVYLPFGAGPRSCVGMRLAQLEIKVALVHIFRRFNVLACEDTEIPL 518 Query: 530 KLQADIILKRAEGFQVRLQPRKRMAKA 556 +L++ L G V++ R+ + A Sbjct: 519 ELKSHTTLGPKNGVMVKITERENLEDA 545 >UniRef50_Q16P39 Cluster: Cytochrome P450; n=7; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 504 Score = 166 bits (404), Expect = 1e-39 Identities = 74/224 (33%), Positives = 139/224 (62%), Gaps = 2/224 (0%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 F++ L++ ++ S + + +D +F G+DT+A L M+ +H ++Q++ +EL Sbjct: 282 FIECLVKYLRAEGETSKDAVYPHIDMTVFAGNDTSAKTICSILLMLAMHPEVQERCYQEL 341 Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447 ++ + D+ ++++D + YLE ET+RL P VP +AR + +I L ++ IPA Sbjct: 342 MEVCPEKDQHISYKDAANLTYLEMVCKETMRLLPAVPFMARITSGDIVL-NDQHTIPANC 400 Query: 448 TLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 T+++ +++HR P ++ PN + FDPDNFLP+ A RH Y+++PFSAGPR+C+G +YA L Sbjct: 401 TIIMGIFQIHRDPRIWGPNADNFDPDNFLPDNVAKRHPYSYIPFSAGPRNCIGTRYAYLS 460 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 K+++ +ILR +R+ + L ++ ++L + G Q+ ++ R Sbjct: 461 SKIMVGSILRKYRLKTSLTMDKLRISCGLLLHISNGCQMAIEHR 504 Score = 77.8 bits (183), Expect = 7e-13 Identities = 48/190 (25%), Positives = 99/190 (52%), Gaps = 6/190 (3%) Query: 87 SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146 S V I +GP V ++DP ++V+L S +DK+ +Y F + + L+ + G W+ R Sbjct: 71 SPVCIHMGPLPHVAIFDPEQLQVVLHSQNCLDKSVQYSFLR--VSETLISAPGHLWKGQR 128 Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDY--MSECTVEILLETAMGV 204 K + P+F +L +F ++FN + +L++ A + + Y +S+CT++ + TA G Sbjct: 129 KALNPSFGPAILTTFAEIFNNKCAILTKRLEEYAGKPERNFYRDISKCTLDQIYATAFGC 188 Query: 205 SKSTQDQSGFEYAMAVMK-MCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH-GLT 262 + Q E ++ + + ++ R +W P+ ++++T K + +L I H +T Sbjct: 189 DFNMQTSLDGERSLDLQEAYMKVMANRFFSVWKYPEFIYRWTAGYKKELELRRIYHETIT 248 Query: 263 KKVIKRKKEE 272 K++++ E Sbjct: 249 CKLVQQVSVE 258 >UniRef50_Q8N118 Cluster: Cytochrome P450 4X1; n=12; Mammalia|Rep: Cytochrome P450 4X1 - Homo sapiens (Human) Length = 509 Score = 166 bits (403), Expect = 2e-39 Identities = 87/228 (38%), Positives = 135/228 (59%), Gaps = 4/228 (1%) Query: 322 QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 ++K FLD++L + +SG + SD ++ +V T + GHDT AA S+ L + ++ + Q Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 ++ EE+ I GD +T+ EM Y C+ ET RL P VP I+R +++ +T P +G Sbjct: 340 ERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP-DG 397 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +PAG T+V++ + LH P V+ NP FDP F E S RH YA++PFSAG R+C+G+ Sbjct: 398 CTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQ 457 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548 ++AM++LKV ++ IL +FRV D ILK G + L+ Sbjct: 458 EFAMIELKVTIALILLHFRVTPD-PTRPLTFPNHFILKPKNGMYLHLK 504 Score = 95.5 bits (227), Expect = 3e-18 Identities = 56/198 (28%), Positives = 102/198 (51%), Gaps = 11/198 (5%) Query: 92 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 148 WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 204 + P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199 Query: 205 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTK 263 + Q S + YA A+ ++ I+ R + D++FK + KL +++ T Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTD 259 Query: 264 KVIKRKKEEFASGKKPSN 281 +I+ +K+ +G K N Sbjct: 260 TIIQERKKSLQAGVKQDN 277 >UniRef50_A1BPR7 Cluster: CYP4AY1; n=2; Ips paraconfusus|Rep: CYP4AY1 - Ips paraconfusus Length = 491 Score = 165 bits (402), Expect = 2e-39 Identities = 88/229 (38%), Positives = 139/229 (60%), Gaps = 7/229 (3%) Query: 321 GQKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 G KK++AFLD LL+ + G +SD I+ +VDT+MF GHDTTA +F L ++ H ++ Sbjct: 261 GGKKKMAFLDHLLQYRDEQGKPLSDAFIRHEVDTVMFAGHDTTAVALAFALYLLAKHPEV 320 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q K E +I ++ +T +D + YL+ + ETLRLYP VP +R + +++ Sbjct: 321 QAKARAEAREIVEGREK-LTIKDIQNLNYLDLVVKETLRLYPSVPFYSRALKEDMVY-QE 378 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 GK +P G ++I Y ++R P VY NP++F P FL + ++ + FSAGPR+C+G Sbjct: 379 GKILPKGLVVLIVAYTVNRNPAVYQNPDQFIPTRFLDKEPVP---FSLLSFSAGPRNCIG 435 Query: 500 RKYAMLKLKVILSTILRNFR-VISDLKESDFKLQADIILKRAEGFQVRL 547 +K+A+L+LKV LS +L F VI D S+ ++A +LK G +++L Sbjct: 436 QKFALLELKVALSKLLLRFEFVIPDSDASEPVVEAVTVLKPKNGIRIKL 484 Score = 104 bits (249), Expect = 7e-21 Identities = 55/173 (31%), Positives = 100/173 (57%), Gaps = 5/173 (2%) Query: 111 LSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSR 170 L+S++ I K + Y K WLG GLLIS G++WR+ RK++ P FH +L+ FI++F ++ Sbjct: 86 LTSNIPIHKGDIYAVLKNWLGGGLLISGGEEWRNSRKILTPAFHFTILEQFIEVFEDATQ 145 Query: 171 AVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDIL 227 + D L E ++ D + Y++ T++++ +T+MGV + Q QS +Y AV +M I+ Sbjct: 146 VLGDVLSAEVTSKGVVDIYPYLTRYTLDVICQTSMGVKLNIQQQSHSDYINAVAEMGKII 205 Query: 228 HLRHTKIWLRPDLLFKFT-DYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKP 279 R D + FT DY K + + + ++H ++ +I+++++ K P Sbjct: 206 VERAFNPLKVYDFTYIFTSDYWK-EKQYVKLLHQVSNSIIEQRRQALEDQKFP 257 >UniRef50_Q170S9 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 497 Score = 165 bits (400), Expect = 4e-39 Identities = 82/229 (35%), Positives = 139/229 (60%), Gaps = 4/229 (1%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 KK++A LDLLL ++ G +SD++I+E+VDT F GHDTTA+ +F L + + D+Q K Sbjct: 269 KKKMALLDLLLRATVDGKPLSDDDIREEVDTFTFAGHDTTASALTFLLFNIAKYSDVQQK 328 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 + EE+ + G S ++ +++YL+ + E+LRLYP VP+IAR + L + Sbjct: 329 LFEEISSVVG-STSELSLHTLNDLRYLDLVIKESLRLYPSVPMIARIATENTKL--DDMP 385 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGPRSCVGRK 501 IP T + + +++HR PD + +P F P+ F R +H + ++PFSAG R+C+G+K Sbjct: 386 IPKCTCVSVDIFQMHRDPDRFEDPESFIPERFDAIRDGGKHNAFTYIPFSAGNRNCIGQK 445 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +A +LK+ + +++ FR+ + + L+A+I+LK AE +R R Sbjct: 446 FAQYELKIAVVKLIQTFRLELPSPDIEPILKAEIVLKPAEKLPIRFITR 494 Score = 114 bits (275), Expect = 5e-24 Identities = 78/254 (30%), Positives = 124/254 (48%), Gaps = 6/254 (2%) Query: 20 LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVG-GSADIFRNIVQ 78 + V+L+P VI + R+L + + L +A E V S +IF+ + + Sbjct: 1 MLIVVLLPLVITLCLVFAFVHRKLLQFPN-LAGPPEWPIAGSATEIVNLSSIEIFKLLRR 59 Query: 79 KSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST 138 + Y + W LVF P E IL++ Y K+E+Y W+G GLLIS Sbjct: 60 YAQQYGTAYKLSFWY-QYTLVFA-KPDIAEKILNTQSYASKSEDYDKVAEWIGYGLLISK 117 Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-EASNFDCHDYMSECTVEIL 197 G+KW RK++ P FH +L+SF+ +FN S + KL S D + T+++L Sbjct: 118 GEKWFKRRKVLTPGFHFKILESFVRVFNEKSDVLCRKLASYGGSEVDVFPTLKLYTLDVL 177 Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257 ETA+G S + Q + F Y AV ++ IL+ R ++ D LF+FT + KL+ Sbjct: 178 CETALGYSCNAQTEDSF-YPAAVEELMSILYWRFFNLFASVDTLFRFTKQYRRFHKLIGD 236 Query: 258 IHGLTKKVIKRKKE 271 T K+I+ K++ Sbjct: 237 TREFTLKIIEEKRK 250 >UniRef50_UPI00015B5723 Cluster: PREDICTED: similar to cytochrome P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 523 Score = 164 bits (398), Expect = 6e-39 Identities = 83/226 (36%), Positives = 134/226 (59%), Gaps = 4/226 (1%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 + RL L+ L++ + ++D E++++ TI DTT SSF L + I+Q+IQDK Sbjct: 300 RPRLMLLEQLIDHNAKTNLMNDTELRDETYTIFTAAQDTTGVISSFALLNLAINQEIQDK 359 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 V EE+ + G+ VT + E+KY E + ETLRLYP P++ R+ +I L + Sbjct: 360 VREEIRNVVGNDS--VTVEHLPELKYTELVIKETLRLYPIAPLMVREATGDIDLETC--T 415 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 +P G ++V+ Y+ HR + +P KF P+ FLPE S RH YA++PFS G R CVG+K+ Sbjct: 416 LPKGCSIVMIPYETHRSTKYWTDPEKFIPERFLPENSVGRHPYAYIPFSGGLRGCVGQKF 475 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548 A++ LK +L ++R R+ S +L+ADI ++ +G+ V ++ Sbjct: 476 AIMCLKTMLVHVIRKVRLTSTQNLETLRLKADISVRSRDGYMVSVE 521 Score = 137 bits (332), Expect = 6e-31 Identities = 78/262 (29%), Positives = 125/262 (47%), Gaps = 4/262 (1%) Query: 13 STFSAINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADI 72 +TF + +++ V W R R LA KL NA F + Sbjct: 28 TTFFLVTTITLMMSFWVFRTLKQWYRDRARTLYLASKLPGPPTLPLIGNAHLFACNPEET 87 Query: 73 FRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGN 132 I Q D + W+GP+L + L +PRD EVIL H K + Y F +P++G Sbjct: 88 LDKIKQIVQSVDTPG--RFWLGPKLFIILAEPRDYEVILGCHKASYKDKMYEFIEPFVGK 145 Query: 133 GLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMS 190 GL+ +G R+HRK I P + L ++ F+ +SR + L+++A FD +M Sbjct: 146 GLVSGSGPVHRAHRKAIMPMLNSKALNEYLKHFDTHSRICSELLEEKAGTGVFDIQPFMV 205 Query: 191 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 250 CT +++ +T +G+ S+Q + E KM +++H R K+WL D +F +TD K Sbjct: 206 HCTFDMIFDTILGMPGSSQKEGHKELVYWTEKMYELVHTRMIKVWLHADWIFSWTDLGKK 265 Query: 251 QTKLLDIIHGLTKKVIKRKKEE 272 Q + +IH + + RKK+E Sbjct: 266 QKEGQHVIHSFIETAVARKKKE 287 >UniRef50_Q17PE3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 513 Score = 164 bits (398), Expect = 6e-39 Identities = 91/221 (41%), Positives = 135/221 (61%), Gaps = 7/221 (3%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 +K F+D LL S S +DEEI V TIM G+DT+ G + + I+ +IQ K Sbjct: 279 RKPQIFIDQLLSLSNSSRPFTDEEILHNVLTIMIAGNDTSGLGVAHACLFLAIYPNIQQK 338 Query: 383 VIEELDQIF---GDSDRPVTFQDTL-EMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438 V +E+ + F G +DR D L +++Y E L E LR P P +ARQ +E+ L Sbjct: 339 VYDEVMKHFPPDGPNDRISLDADFLRQLEYTEMFLKEVLRHCPVAPTVARQNLKELEL-- 396 Query: 439 NGKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 497 +G +IPAG TL + + LHRR D++ P+ KFDP+NF PER RH YAF+PFS+G R+C Sbjct: 397 DGVRIPAGNTLSFSFFALHRRKDIWGPDAEKFDPENFAPERCEKRHPYAFMPFSSGSRNC 456 Query: 498 VGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILK 538 +G +YAM+ +KV++ I+RNF + ++L+ S + + + LK Sbjct: 457 IGGRYAMISMKVMIVYIVRNFSLKTNLRHSHLRYKFGMTLK 497 Score = 79.4 bits (187), Expect = 2e-13 Identities = 50/208 (24%), Positives = 101/208 (48%), Gaps = 5/208 (2%) Query: 85 HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144 H+ + K +GP + + + P + +LS ++K Y F + L +G+ + + W+ Sbjct: 69 HDRMFKHLLGPIMGIGISHPDLMHKVLSHPDCLEKPFFYNFVQ--LEHGIFSAEYKLWKG 126 Query: 145 HRKLIAPTFHLNVLKSFIDLF-NANSRAVVDKLK-KEASNFDCHDYMSECTVEILLETAM 202 RK + PTF++ +L SFI +F + +SR V D K D + S+CT+E++ T + Sbjct: 127 QRKALNPTFNMKILNSFISIFEDCSSRMVADLFKCANGETVDMFQFTSKCTLEMVCATTL 186 Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262 G S + + E+ + + +++ R + L D +++ T Y + + K+ I + Sbjct: 187 G-SNVLEREGSDEFLRNMEGLFELVGKRMLSVELFLDSIYRLTSYYRKEMKIRKKIEEFS 245 Query: 263 KKVIKRKKEEFASGKKPSNLNETATTSE 290 +I+ K+ E +L+ +T E Sbjct: 246 GNIIREKRREHMFCLNQQHLHNASTPKE 273 >UniRef50_O46054 Cluster: Cytochrome P450 4ae1; n=1; Drosophila melanogaster|Rep: Cytochrome P450 4ae1 - Drosophila melanogaster (Fruit fly) Length = 496 Score = 164 bits (398), Expect = 6e-39 Identities = 78/225 (34%), Positives = 140/225 (62%), Gaps = 5/225 (2%) Query: 327 AFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 A LD LL ++ G ++D++I+++V+T +FEGHDTT + SF L ++ H+ +Q K+ EE Sbjct: 274 ALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEE 333 Query: 387 LDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445 L +G D R V D + YL + E+LRLYPP+P +AR + +++ + IP Sbjct: 334 LRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEG--YIPV 391 Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505 GT +V+ ++L R ++ +P F P+ L E + Y+++PFSAGPR+C+G+K+A+L Sbjct: 392 GTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALL 451 Query: 506 KLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 ++K +++ ++R+++++ +D + I+L+ G V L+PR Sbjct: 452 EMKTMVTKVIRHYQLLP--MGADVEPSIKIVLRSKSGVNVGLRPR 494 Score = 87.4 bits (207), Expect = 9e-16 Identities = 52/182 (28%), Positives = 97/182 (53%), Gaps = 16/182 (8%) Query: 103 DPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFI 162 +PR ++ +L + K Y + WLG+GLL+S G++W + RK+I PTFH ++L+ F+ Sbjct: 86 EPRHIDALLQGQHQLKKGTMYFALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFV 145 Query: 163 DLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMA 219 ++F+ S +V++L+ + + + + ++I+ ETAMGV+ Q E A Sbjct: 146 EVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGADS-EVVHA 204 Query: 220 VMKMCDILHLRHTKIWLRPDLLFKF-------TDYAKNQTKLLDIIHGLTKKVIKRKKEE 272 V + +IL R ++RP LLF + + K Q ++ +H T +I++++ Sbjct: 205 VKDLTNILATR----FMRPHLLFPHLFRLCWPSGFRKQQAGVI-CLHEFTNGIIEQRRRL 259 Query: 273 FA 274 A Sbjct: 260 LA 261 >UniRef50_Q9VLZ7 Cluster: Probable cytochrome P450 4d21; n=5; Sophophora|Rep: Probable cytochrome P450 4d21 - Drosophila melanogaster (Fruit fly) Length = 511 Score = 163 bits (397), Expect = 8e-39 Identities = 80/235 (34%), Positives = 145/235 (61%), Gaps = 6/235 (2%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G K ++ LD+LL+++ +SD +I+E+VD +F G DTT +G S L + H +Q Sbjct: 280 GGKAKMTLLDILLQATIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQ 339 Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 + + EEL + G D D VT LE+KYL+ + ET+RL+PPVPI+ R + +++ + Sbjct: 340 ECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKI--G 397 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP-ERSANRHYYAFVPFSAGPRSCV 498 IP T++++ Y ++R P+ +P+P F P+ ++ + ++N A++PFS+GP++C+ Sbjct: 398 EITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCI 457 Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRM 553 G+K+A L++K ++S ++R++ ++ +D K IL + G V L+PR R+ Sbjct: 458 GQKFANLQMKALISKVIRHYELLP--LGADLKATYTFILSSSTGNNVGLKPRTRV 510 Score = 120 bits (290), Expect = 8e-26 Identities = 70/204 (34%), Positives = 113/204 (55%), Gaps = 9/204 (4%) Query: 75 NIVQKSADYDHE--SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGN 132 N +Q+ DY ++ ++WI L++ D + E ILSS + KA YRF + +LG+ Sbjct: 55 NFIQRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGD 114 Query: 133 GLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHD---YM 189 GLL+STG KW S RK++AP FH L++F+++ + NS +V+KLK A C D ++ Sbjct: 115 GLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFV 174 Query: 190 SECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD--- 246 S +++ ETAMGV + Q++ F Y A+ + I R + +R + LF Sbjct: 175 SLEALDVTTETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLV 234 Query: 247 YAKNQTKLLDIIHGLTKKVIKRKK 270 Y + Q K + I+ T KVI+ ++ Sbjct: 235 YRRLQ-KDIAIMQDFTDKVIRERR 257 >UniRef50_Q4STK8 Cluster: Chromosome undetermined SCAF14158, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF14158, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 612 Score = 163 bits (395), Expect = 1e-38 Identities = 117/413 (28%), Positives = 201/413 (48%), Gaps = 38/413 (9%) Query: 134 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCH----DYM 189 LL+S G+ W R+L+ P FH ++LK+++ FN ++ + DK ++ A+ H + + Sbjct: 174 LLLSNGEVWLRKRRLLTPAFHFDILKNYVAKFNTSTNTMHDKWRRLAAEGPTHVEAFEDV 233 Query: 190 SECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAK 249 + T++ LL+ A Q QS EYA A++++ D++ R +I D ++ T K Sbjct: 234 TLMTLDSLLKCAFSYDSDCQ-QSSSEYASAIVQLSDLIIERRQRILHHWDWIYWRTRQGK 292 Query: 250 NQTKLLDIIHGLTKKVIKRKK-------EEFASGKKPSNLNETATTSEPSTGK-LTS--- 298 + L I+H T+ V++ ++ E A GKK + + S+ GK LT Sbjct: 293 RFQQALSIVHKFTRDVVQERRTLIGQKGEMAAQGKK--DFVDIILLSKDEDGKGLTDEEI 350 Query: 299 -VEGLSF---GQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTI 354 E +F G+ + R L L L SS S +++S Sbjct: 351 QAEANTFMFAGEQWLMLKLVDVSSNLTSGTRSVNLVLRLGSSCSQMSLS---------AC 401 Query: 355 MFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE-LDQIFGDSDRPVTFQDTLEMKYLERCL 413 GHDTTA+ + L + H Q+K +E +D + G + ++D + + C+ Sbjct: 402 SPTGHDTTASAICWSLYNLARHDHYQEKCRKEVMDLMEGRDVHEINWEDLSSLPFTTMCI 461 Query: 414 METLRLYPPVPIIARQVNQEITLPSNGKK------IPAGTTLVIATYKLHRRPDVYPNPN 467 E+LRL+ PV + R+ Q++ LP K P G +++ Y H P V+ NP+ Sbjct: 462 RESLRLHSPVQAVTRRYLQDVELPGGHTKNETIACYPEGAICLVSIYGTHHNPAVWTNPH 521 Query: 468 KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520 FDP F P +AF+PFS+GPR+C+G+K+A+ +L+V+++ L FR+ Sbjct: 522 DFDPLRFDPTNQKGLSSHAFIPFSSGPRNCIGQKFALAELRVVVALTLLRFRL 574 >UniRef50_Q177R7 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 496 Score = 162 bits (393), Expect = 3e-38 Identities = 77/207 (37%), Positives = 131/207 (63%), Gaps = 2/207 (0%) Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404 +EI + + TI+ G DT+A +F + ++Q+ Q KV EE+ ++F +S+ +T + Sbjct: 290 QEIIDNIITIVGAGTDTSATAIAFTFLQLAMYQEHQQKVYEEIVKVFPESEPHITTEALK 349 Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY- 463 +++Y + L E LRLYP PI+ R+ +ITL G ++P G L I Y +HRR DV+ Sbjct: 350 KLQYTKMVLNECLRLYPVAPILLRENTADITL-CGGVRVPKGNILTIDVYNIHRRKDVWG 408 Query: 464 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 523 P+ ++F P+ F PERSA RH +AF+ FS G R+C+G +YAM+ +K+++ +L+NFR + Sbjct: 409 PDADEFIPERFSPERSAGRHPFAFLTFSGGSRNCIGSRYAMISMKIMMVYLLKNFRFKTK 468 Query: 524 LKESDFKLQADIILKRAEGFQVRLQPR 550 ++E D + + D +L+ G V+++ R Sbjct: 469 IREEDIRYKFDALLRIEGGHLVQIEKR 495 Score = 77.4 bits (182), Expect = 9e-13 Identities = 50/195 (25%), Positives = 97/195 (49%), Gaps = 7/195 (3%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120 N L F G + DI + + A +++ ++++GPR+L+ DP + I++ ++K Sbjct: 42 NGLLFFGKN-DIKKFHKLRKAFDRKDALFRLYLGPRMLLCTSDPTVAQAIMTDANCMEKP 100 Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-- 178 Y+FF L G+ + W+ RK + P F+ +L+SF+ +F S+ ++ +L Sbjct: 101 YVYKFFN--LNEGVFAAKTHIWKGQRKALNPAFNSKILESFVSIFCEVSKTMIQRLDTVG 158 Query: 179 EASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRP 238 + + ++ S CT+E++ T +G + DQ E + + I R K +L Sbjct: 159 KGDTINIMEHASRCTLEMVCSTTLGFNVDIFDQID-EMGHKIEQFFYIAARRILKFYLHV 217 Query: 239 DLLFKFT-DYAKNQT 252 D ++++T DY QT Sbjct: 218 DSIYRWTKDYKDEQT 232 >UniRef50_UPI0001555B83 Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily V, polypeptide 2, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily V, polypeptide 2, partial - Ornithorhynchus anatinus Length = 412 Score = 161 bits (392), Expect = 3e-38 Identities = 76/206 (36%), Positives = 119/206 (57%), Gaps = 2/206 (0%) Query: 69 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP 128 S D+F+ ++Q + ++ H + K+WIGP +V LY VEVILSS I K+ YRF +P Sbjct: 121 SVDLFQQVIQYTEEFRHMPLWKLWIGPVPMVILYHAESVEVILSSSKQISKSYVYRFLEP 180 Query: 129 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCH 186 WLG GLL STG KWRS RK++ PTFH ++L+ F+ + N +++ +V+K +K FDC Sbjct: 181 WLGLGLLTSTGGKWRSRRKMLTPTFHFSILEEFVGVMNEHAQTLVEKFEKHVDRDAFDCF 240 Query: 187 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 246 ++ C ++I+ ETAMG + Q EY + +M D++ R WL D + Sbjct: 241 MDITLCALDIICETAMGRNIQVQTNGDSEYVRTIYRMSDLIQRRILMPWLWLDPCYLLFQ 300 Query: 247 YAKNQTKLLDIIHGLTKKVIKRKKEE 272 + + L ++H T +VI + +E Sbjct: 301 EGREHRQKLRVLHEFTDRVIAERSKE 326 Score = 72.5 bits (170), Expect = 3e-11 Identities = 36/69 (52%), Positives = 49/69 (71%), Gaps = 1/69 (1%) Query: 324 KRLAFLDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 +R AFLDLLLE++ +S +++E+VDT MFEGHDTTAA SF L ++G D Q K Sbjct: 344 RRRAFLDLLLETADDARNGLSLRDVREEVDTFMFEGHDTTAAAMSFVLYLLGSCPDAQRK 403 Query: 383 VIEELDQIF 391 V +ELD++F Sbjct: 404 VNDELDRVF 412 >UniRef50_Q16L50 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 428 Score = 161 bits (391), Expect = 4e-38 Identities = 83/231 (35%), Positives = 135/231 (58%), Gaps = 2/231 (0%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G KK F++ LL+ Q I E+I + + T+ F G+DTTA S L M+ +H DIQ Sbjct: 199 GAKKIPIFVEKLLDEIQKSGHIKREDIDDHIVTMCFAGNDTTATTMSNILLMLAMHPDIQ 258 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 ++V +E+ D ++ V+ +D ++ Y E ET+R + P+I R Q++ L ++ Sbjct: 259 ERVYQEIIAACPDRNQQVSIEDAGKLTYTEMVCKETMRHFSIAPVIGRTATQDVKL-NDD 317 Query: 441 KKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 IPA +TL+ YKLH P + P+ F+PDNFLP+ A RH Y+F+PFS GPR+C+G Sbjct: 318 ITIPANSTLICCFYKLHMDPKNWGPDVKNFNPDNFLPDLVAKRHPYSFLPFSGGPRNCLG 377 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +YA L +K++L ILR +R+ + L ++ + +K +G + ++ R Sbjct: 378 VRYAWLSMKIMLVHILRRYRLRTTLTMDTITVKFNSFMKIEDGCPITVEER 428 Score = 87.4 bits (207), Expect = 9e-16 Identities = 53/179 (29%), Positives = 92/179 (51%), Gaps = 11/179 (6%) Query: 93 IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPT 152 +GP + +F+Y P ++V+L+S ++K +Y FF+ + G+ + W+ RKLI P+ Sbjct: 1 MGPMVYIFVYTPEQLQVVLNSPHCLEKPLQYSFFQ--VSRGIFSAPVDLWKILRKLITPS 58 Query: 153 FHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSE---CTVEILLETAMGVSKSTQ 209 F +L SF+ +FN S +V+++ K DY SE C ++ + TA GV Q Sbjct: 59 FGPGLLSSFVPIFNEKSSVMVEQMAKNVGK-PQRDYYSEIVLCFMDTICNTAFGVDCDLQ 117 Query: 210 -DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD----YAKNQTKLLDIIHGLTK 263 +G EY K DI+ R+ K W + +++FT+ + K K L ++ T+ Sbjct: 118 RSPAGAEYVETQEKYIDIVTERYLKPWQYLNFIYRFTNAYQIFKKRHGKFLALLTQATR 176 >UniRef50_Q6SPQ6 Cluster: CYP4BB1; n=2; Protostomia|Rep: CYP4BB1 - Nereis virens (Sandworm) Length = 508 Score = 161 bits (390), Expect = 6e-38 Identities = 81/231 (35%), Positives = 140/231 (60%), Gaps = 6/231 (2%) Query: 323 KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 +K L FLD+LL++ + G +SD EI+ +VDT MFEGHDTTA+G S+ L + H + Q Sbjct: 281 RKYLDFLDILLQARDEDGTGLSDLEIRNEVDTFMFEGHDTTASGISWALYSLAKHPEFQK 340 Query: 382 KVIEELDQIFGD-SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 K +E+D++ D ++ + + D ++ YL CL E++RL+ PVP+I+RQ+ IT+ +G Sbjct: 341 KAQQEIDELLADRKNKWIMWDDLNQLPYLTMCLKESMRLWCPVPVISRQLLNPITI--DG 398 Query: 441 KKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 +P T I LH P V+ + +++ P+ FLPE +AF+PFSAGPR+C+G Sbjct: 399 VTLPPHTLFDINIIALHHNPTVWGEDHDEYKPERFLPENINKMDNFAFLPFSAGPRNCIG 458 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 + +A ++K ++ I++ F + D + + +++ + G ++ + PR Sbjct: 459 QNFAFNEMKTTIARIIQRFDLSVDESHPVYP-RPEVVTRAIHGIKLFMNPR 508 Score = 49.2 bits (112), Expect = 3e-04 Identities = 48/207 (23%), Positives = 90/207 (43%), Gaps = 11/207 (5%) Query: 75 NIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLG 131 N QKS + + ++W GP + + L P +++++ + + D Y +PWLG Sbjct: 64 NGYQKSMAAKYNRLWRMWFGPFVPFISLCHPDTIKILVKTEEPKFTDGNAGYLLAEPWLG 123 Query: 132 NGLLISTGQKWRSHRKLIAPTF---HLNVLKSFIDLFNANS--RAVVDKLKKEASNFDCH 186 N LL+ K ++ +F H L + N NS ++ K +KE + Sbjct: 124 NRLLLKCWTKVEEKQETPDTSFSFWHPQELHFCLQCGNRNSDEKSGQQKDRKERA-LTFR 182 Query: 187 DYMSECTVEILLETAMGVSKSTQDQ-SGFEYAMAVMKMCDILHLRHTKIWLR-PDLLFKF 244 CT+ I+L A + Q+ YA+AV+ + ++ R ++R L+ Sbjct: 183 RIFRLCTLSIILRCAFSYDEKIQETGERHPYAVAVLDLSRLMVERAFNPFVRMSKFLYGL 242 Query: 245 TDYAKNQTKLLDIIHGLTKKVIKRKKE 271 T + K D +H + + VI +++E Sbjct: 243 TANGRTFFKHCDYVHKVAETVISQRRE 269 >UniRef50_Q17PE0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 462 Score = 160 bits (388), Expect = 1e-37 Identities = 86/233 (36%), Positives = 137/233 (58%), Gaps = 4/233 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 G K FLD +L ++++G DEEI+ V T++ G+DT+ ++ ++G++ IQ Sbjct: 229 GYHKPQIFLDQILSANRAGKPFDDEEIQHNVRTMIAAGNDTSGQLMAYACLLLGMYPHIQ 288 Query: 381 DKVIEELDQIFGDSDRP-VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 +KV E+ ++ + + ++ + + Y E + E LRL P P IAR I L Sbjct: 289 EKVYSEIIELIPLTRKESISVEQLKTLTYTEMFMFECLRLCPIAPNIARLNMTPIEL--E 346 Query: 440 GKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 G IPAG I+ Y LHRR D++ P+ +FDP+ F PERS RH YAF+PFS G R+C+ Sbjct: 347 GITIPAGHIFFISFYSLHRRKDIWGPDAEQFDPERFSPERSVGRHLYAFLPFSGGSRNCI 406 Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 G +YAM+ +K++L +LR +R +DLK SD K + D++L V+++ R+ Sbjct: 407 GWRYAMMSMKLMLVYLLREYRFRTDLKLSDLKFKFDMMLVLVFEHWVKIEKRR 459 Score = 71.7 bits (168), Expect = 5e-11 Identities = 58/229 (25%), Positives = 115/229 (50%), Gaps = 13/229 (5%) Query: 61 NALEFVGGSADIFRNIVQKSADY-DHES-VVKIWIGPRLLVFLYDPRDVEVILSSHVYID 118 NAL+FVG + + + +K AD +H + + ++ +G L DP + IL+ ++ Sbjct: 5 NALQFVGKNGE---ELFKKFADMLNHPAKLFQMRMGVLRLFCTNDPDVAQKILTQ--CLE 59 Query: 119 KAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK 178 K Y FFK L GL + W+ RK + TF+L +L SFI +F SR +V++L+ Sbjct: 60 KPFLYDFFK--LDYGLFSAHYGLWKQQRKALNSTFNLKILHSFIPIFEECSRKLVNRLQN 117 Query: 179 E---ASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIW 235 + + ++S+CT+E++ T +G+ + Q +SG + + ++ DI+ R I Sbjct: 118 HVGCSKPINLAQFVSQCTLEMVCGTTLGM-EHLQQESGSRFLHHIERVMDIMGERILSIP 176 Query: 236 LRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNE 284 ++ L+ FT + L + ++I + + + ++ + ++E Sbjct: 177 MQITALYFFTPMFWQEMHSLKMNRQYAAEIIDEGRRKMKANEQSNTIDE 225 >UniRef50_Q7QCC3 Cluster: ENSANGP00000012179; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000012179 - Anopheles gambiae str. PEST Length = 504 Score = 156 bits (379), Expect = 1e-36 Identities = 85/232 (36%), Positives = 133/232 (57%), Gaps = 8/232 (3%) Query: 323 KKRLAFLDLLLE---SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 +K F+D L++ + S SDEEI + + T++ G++T+A + ++ +H I Sbjct: 275 RKPQIFIDQLMKMPLTDPSARHFSDEEISDHIYTMIVAGNETSATQLAHTCLLLAMHPHI 334 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q K EE+ + D+ +T + ++ YLE L E +RL P PI+ RQ EI L + Sbjct: 335 QTKAYEEVAGLVFSPDQEITIELMKDLHYLECVLKEAMRLMPVAPIVGRQSRAEIVL--D 392 Query: 440 GKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 G +IP G+ + Y LHRR DV+ P ++F+P FL + RH YA +PFS GPR C+ Sbjct: 393 GHRIPQGSVFLFHFYALHRRKDVWGPTADEFEPGRFLAD--GGRHPYAHLPFSGGPRGCI 450 Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 G +YAM+ LK +L+ +LRN+ +++DL+ D + Q I L A VRL+ R Sbjct: 451 GYRYAMMSLKTLLAQLLRNYELMTDLRYEDIRYQYQISLNLAFPHAVRLRRR 502 Score = 86.6 bits (205), Expect = 2e-15 Identities = 59/217 (27%), Positives = 117/217 (53%), Gaps = 11/217 (5%) Query: 61 NALEFVGGS-ADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDK 119 N +F+G S ++F +V H+ + + G +L + L P V+ +L+ K Sbjct: 43 NVGDFLGKSPGEVF--LVLDRHFRQHDRLFTLRFGSQLAIGLTHPELVQKVLTHPDCQAK 100 Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE 179 + Y+ + L NGLL + W+ HRK + TF+ +L+SF+ +FN ++ +V +L + Sbjct: 101 PDLYKVVR--LPNGLLAAKYDVWKVHRKTLNSTFNARILESFVPIFNDCTQRLVGRLDRY 158 Query: 180 ASNFD-CH--DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMC-DILHLRHTKIW 235 A + D C+ +Y+S CT+E++ T++G ++ G E +A +++ + +R I+ Sbjct: 159 ARSGDRCNILEYISACTLEMISRTSLG--GKVLEREGAEQFIANLEVALKTIGVRIFNIF 216 Query: 236 LRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272 L D +++FT + + + ++I T K+I+ K+EE Sbjct: 217 LHIDFIYQFTALYRKEMRAINICQQFTSKIIQAKREE 253 >UniRef50_UPI0000D56467 Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 470 Score = 156 bits (378), Expect = 2e-36 Identities = 79/226 (34%), Positives = 141/226 (62%), Gaps = 8/226 (3%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 FL+ LL+ S++ ++D++I E+ T++ +TTA + L + I +Q+K+ EEL Sbjct: 243 FLNNLLKMSEN---MTDDDILEETQTMLVAASETTALTMATVLLTLAIFPQVQEKIYEEL 299 Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447 D I ++D +T + +M YLE + ET+R+ P VP I R++ +++ L N +P G+ Sbjct: 300 DAILWNTDE-ITLEHINKMVYLEAVIKETMRILPTVPFINRRMTEDLHL--NDCVVPTGS 356 Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507 ++I+ +H P ++ NP+KFDP+ FL ER NR AF+PF GPR+C+G K+AML + Sbjct: 357 NIIISIKNIHDSPLLWENPDKFDPERFLTERDPNRSRCAFMPFGYGPRNCIGFKFAMLSM 416 Query: 508 KVILSTILRNFRVISDLKESDFKLQA--DIILKRAEGFQVRLQPRK 551 KV+++++L+NF + +S +++ +I+ K +G++V+ RK Sbjct: 417 KVMMASLLKNFTFEPAVYKSIAEIECFYNIVAKPKKGYKVKFSERK 462 Score = 99.5 bits (237), Expect = 2e-19 Identities = 63/210 (30%), Positives = 105/210 (50%), Gaps = 7/210 (3%) Query: 65 FVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR 124 F GG D+++ +++ + + KIW+G L+ P D E+ILS K + Sbjct: 18 FHGGYDDMYQAMLRLTKS--QPPLFKIWLGQDLIFVTSRPEDCEIILSK--CFTKGKFAT 73 Query: 125 FFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SN 182 F P GLL + KW+SHRK+I P+F++ +L SFI +FN +S+ +V+K++K A + Sbjct: 74 FMDPIFWEGLLTAPAIKWKSHRKIINPSFNIQILNSFIGVFNKHSKKLVEKMRKHAGSDS 133 Query: 183 FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLF 242 D ++ T++I ET M + + + EY +K R +W P+ ++ Sbjct: 134 VDVSYWLFRNTIDISCETLMDID-ADLIKGQEEYIDDCIKAEKYSSTRMIGVWYHPEFIW 192 Query: 243 KFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272 K + K D I +K+IK KK E Sbjct: 193 KHSPLGKLTKATSDKILDFVRKIIKLKKLE 222 >UniRef50_Q16E69 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 348 Score = 156 bits (378), Expect = 2e-36 Identities = 75/179 (41%), Positives = 116/179 (64%), Gaps = 6/179 (3%) Query: 324 KRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383 +R A LD LL +S++ I +E I+E+VDT MFEGHDTTA+ +F ++ HQ+ Q ++ Sbjct: 167 QRYALLDTLL-ASEAKNQIDEEGIREEVDTFMFEGHDTTASAFTFIFLVIANHQEAQRQL 225 Query: 384 IEELDQIFGDSDRP---VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 +EE++ + +P ++ D E+K+++R + E LRLYPPVP I+R + ++ L Sbjct: 226 VEEIEAMIAGRIKPTEPLSMHDYSELKFMDRVIKECLRLYPPVPFISRAILEDALL--GD 283 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 + IP + + + LHR PD +P+P +FDPD FLP R+ YA+VPFSAGPR+C+G Sbjct: 284 RFIPKDSMANLHIFDLHRDPDQFPDPERFDPDRFLPANVEKRNPYAYVPFSAGPRNCIG 342 Score = 44.0 bits (99), Expect = 0.011 Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257 +ETAMGV + + EY + ++ +L LR WL + ++ + + K+L Sbjct: 72 IETAMGVKLDSMSMAD-EYRAKIQEVIKLLLLRVMNPWLVEEFPYRLLGFRRRLMKVLKP 130 Query: 258 IHGLTKKVIKRKKEEFASGKK 278 IH T+ +IK++++ F + K Sbjct: 131 IHAFTRSIIKQRRDLFHANVK 151 >UniRef50_UPI0000D56469 Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily v, polypeptide 2; n=1; Tribolium castaneum|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily v, polypeptide 2 - Tribolium castaneum Length = 392 Score = 155 bits (377), Expect = 2e-36 Identities = 78/207 (37%), Positives = 128/207 (61%), Gaps = 5/207 (2%) Query: 347 IKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEM 406 I+E++ TI+ ++TA L+++GI+ +IQ KV +ELD IFG DR T +D +M Sbjct: 187 IEEELQTILITSSESTALTVGMILTVLGIYPEIQKKVSKELDSIFGHDDRETTLEDVQKM 246 Query: 407 KYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNP 466 KYLE + ET R+ P VP++AR +++I L + IPAG+ +VI +++ + D + NP Sbjct: 247 KYLECVIKETSRVLPAVPLLARLADKDIKL--DNYTIPAGSIIVIPIWQIGKNADFWKNP 304 Query: 467 NKFDPDNFLPER-SANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLK 525 KFDPD FLPE NR +F+PFS GPR+C+G +Y+ + +KV+ +TILR + + Sbjct: 305 KKFDPDRFLPENCDPNRPRSSFIPFSYGPRNCIGFQYSNMLVKVLTATILRKYTIKCPQY 364 Query: 526 ES--DFKLQADIILKRAEGFQVRLQPR 550 S ++ I + GF+++++ + Sbjct: 365 TSFEQVEIIFSITARPKHGFKIQMEKK 391 Score = 73.3 bits (172), Expect = 2e-11 Identities = 53/191 (27%), Positives = 87/191 (45%), Gaps = 10/191 (5%) Query: 5 NAENVVPTSTFSAINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALE 64 N E + TS + LF VL W +RR LY K++ A Sbjct: 2 NFETINTTSALTWALLFIVLFFIIKYNW------NRRWLYYYGSKIDGPFAWPIIGIAHY 55 Query: 65 FVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR 124 F+GG +F N + K + + K W+G L+V +DVE+IL++ +K + Y Sbjct: 56 FIGGQK-VFYNQLTKLFEAQ-PPIFKFWLGQDLVVATSRLKDVEIILNN--CFEKPKFYN 111 Query: 125 FFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD 184 F GNGLL + W+ RK+I F L VL S++D+F+ ++ ++ +++ D Sbjct: 112 FMCEVTGNGLLTARENIWKERRKMINQAFSLKVLHSYVDIFSKRAKCLISWFEEDFGKED 171 Query: 185 CHDYMSECTVE 195 + CT + Sbjct: 172 VFFKLYRCTFD 182 >UniRef50_Q176V3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 498 Score = 155 bits (377), Expect = 2e-36 Identities = 74/218 (33%), Positives = 134/218 (61%), Gaps = 4/218 (1%) Query: 323 KKRLAFLDLLLESSQ-SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 K+ L LD ++ + G SD E+ E + T++ G DT+A ++ + ++ ++Q+ Sbjct: 269 KQHLNALDQIITMKRPDGTGFSDLEVNEHLYTLIGAGTDTSALNVAYTCLYLAMYPEVQE 328 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 KV+ E++Q+F + V ++ +++Y E + E LRL+P VP+ ARQ I L +G Sbjct: 329 KVLTEINQVFYSPEVEVNIENLKQLEYTEMVIKEILRLFPAVPLGARQTMSAIEL--DGI 386 Query: 442 KIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +IP ++ + + LHRR D++ P+P +FDP+ F PE RH +A++PFS G R+C+G Sbjct: 387 RIPKDQIIIFSMFTLHRRKDIWGPDPEQFDPERFRPEAIEARHPFAYLPFSGGLRNCIGH 446 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILK 538 +YAM +++IL I++ F + +++K +D KL+ ++ LK Sbjct: 447 RYAMNVMRIILLRIMQKFEIQTNMKPTDLKLKFEVTLK 484 Score = 76.6 bits (180), Expect = 2e-12 Identities = 50/195 (25%), Positives = 99/195 (50%), Gaps = 9/195 (4%) Query: 86 ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIS-TGQKWRS 144 E + K+ +GP+ L+ + P ++ +L+ + DK Y F + LGNGL+ +G++W Sbjct: 66 ERMGKLMLGPKPLITISHPDLMQQVLTRNDLYDKPFLYEFLR--LGNGLITERSGERWLQ 123 Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSECTVEILLETA 201 RKL+ PTF+ ++L SF+ +A + +V KL+ A S D + ++ CT+EI + T Sbjct: 124 TRKLLGPTFNTSMLTSFLSTMDARTMKMVSKLQSLADGHSEIDIYPFLLTCTLEIAISTT 183 Query: 202 MGVSKSTQDQSG-FEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHG 260 MG + + G +Y + + R ++ + ++K + K + I + Sbjct: 184 MG--RMDDEMPGQQDYIRNLEIFLKAVGERLVNVYYFIEPIYKLSKAYKIHDEARRICNE 241 Query: 261 LTKKVIKRKKEEFAS 275 T +++ +++ E S Sbjct: 242 FTHRIVSKRRFEIQS 256 >UniRef50_Q178V0 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 502 Score = 155 bits (375), Expect = 4e-36 Identities = 78/225 (34%), Positives = 132/225 (58%), Gaps = 3/225 (1%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 F+D +L + + IS + + EQ+ TIM G+DT+A + + I ++Q+KV +E+ Sbjct: 280 FIDQVLSGNNTEADISTQNLSEQILTIMAAGYDTSANMVAHSCLFLAIFPELQEKVAQEI 339 Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447 + D ++ +T + ++ YL++ E LRL P IAR +I L +G +IP G Sbjct: 340 QTVLPDCEQELTAETLKDLPYLDKFFKECLRLTPVGSTIARVNMTDIEL--DGCRIPKGN 397 Query: 448 TLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 + Y LHRR D++ P +FDP+NF PERS RH +AF+PFS G R+C+G +YAM+ Sbjct: 398 IFIFNFYVLHRRKDIWGPYAEQFDPENFSPERSKGRHPFAFLPFSGGSRNCIGARYAMIS 457 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 K+++ ++RNFR+ + ++ D K + ++ L A + L+ R+ Sbjct: 458 NKIMIIHLVRNFRMSTKIRFEDLKYRINVTLNLAFKHLITLEARR 502 Score = 72.9 bits (171), Expect = 2e-11 Identities = 44/148 (29%), Positives = 80/148 (54%), Gaps = 7/148 (4%) Query: 61 NALEFVGGSADI-FRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDK 119 +A F+G S + F N + D + K W+GP+L+ ++ P V+ +L+ +K Sbjct: 44 SATVFLGHSEERRFENFMNMLRQVDR--IGKGWLGPQLMFYVAHPELVQKVLTDPNCSEK 101 Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK-- 177 Y F + L +GL + W+ +RK + PT ++ +L SF+ +F SR++V+KLK Sbjct: 102 PFFYEFSR--LTHGLFSAKYSIWKPNRKALNPTMNVKMLNSFVPIFERFSRSMVEKLKCY 159 Query: 178 KEASNFDCHDYMSECTVEILLETAMGVS 205 E + D D+ +EC +E++ T +G + Sbjct: 160 PEGTPVDILDFTTECALEMVCGTTLGTA 187 >UniRef50_UPI0000D5558E Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=2; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 495 Score = 151 bits (367), Expect = 4e-35 Identities = 70/206 (33%), Positives = 120/206 (58%), Gaps = 3/206 (1%) Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404 ++ + + T M DT ++ +F M+G + IQD V++EL ++ G + D Sbjct: 291 QDCTDHLMTFMATSQDTQSSAVAFTCMMLGAYPHIQDLVVQELREVMGKKTS-LDLTDVS 349 Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464 ++KYLE CL E++RL+P P I R ++ IP G T++++ Y HR P+ + Sbjct: 350 QLKYLEMCLKESMRLFPVGPFIFRDTTEDFQFDK--MVIPEGVTVILSIYHAHRSPEHWE 407 Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDL 524 P++F P++F PE + RH AF+PFSAGPR C+ + Y+ +K++L+TI+ N+ + Sbjct: 408 KPDEFYPEHFAPEAMSKRHPCAFIPFSAGPRRCIAQHYSYTYMKILLATIVLNYEIECRF 467 Query: 525 KESDFKLQADIILKRAEGFQVRLQPR 550 K D KL ADI ++ +G+ ++L+ R Sbjct: 468 KAEDVKLIADISIRPQQGYLIKLKDR 493 Score = 126 bits (305), Expect = 1e-27 Identities = 76/241 (31%), Positives = 124/241 (51%), Gaps = 13/241 (5%) Query: 20 LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79 + ++LLV +I + RR+LY A KL N F + +IF N + Sbjct: 1 MLFLLLVILIICCLVKYHWDRRKLYLFAAKLQGPKAYPVVGNGPLFWCKNEEIFNNFMAA 60 Query: 80 SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139 +A Y S V++W+GP+L++F+ DP +++IL S K+ YRF +P+LG GL S+G Sbjct: 61 TAPYP--SPVRLWVGPKLVLFVKDPNQLQLILQSSKITTKSFLYRFLEPFLGKGLFTSSG 118 Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS--NFDCHDYMS----ECT 193 + + HRKL+ P F +++ + LF +S+ V+ L+K A+ F+ ++ E T Sbjct: 119 PRQKHHRKLLQPLFSQRMIEGYCHLFQKHSKKFVEDLRKNANGPEFNISTFLQFTAFEAT 178 Query: 194 VEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTK 253 +++LLE + T E V K +I+ R WL D+ FK + Y + QTK Sbjct: 179 MDLLLE-----DQDTHSIDYNEIPNYVRKFYEIVFTRVKSFWLHLDIFFKLSSYYREQTK 233 Query: 254 L 254 L Sbjct: 234 L 234 >UniRef50_Q9VGB4 Cluster: Probable cytochrome P450 313a2; n=2; Drosophila melanogaster|Rep: Probable cytochrome P450 313a2 - Drosophila melanogaster (Fruit fly) Length = 493 Score = 150 bits (364), Expect = 8e-35 Identities = 144/537 (26%), Positives = 245/537 (45%), Gaps = 60/537 (11%) Query: 23 VLLVPAVILWYAY-WRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSA 81 +L+ ++ILW + W SRR+LY L +L N++ ++ I R + Sbjct: 6 LLIAASLILWIRFLW--SRRKLYMLMMQLPGRMGLPLLGNSVRYL----IISRGKMSSRT 59 Query: 82 DY--DHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEY-RFFKPWLGNGLLIST 138 Y H S WIG +V DP+ E +L+S I+++ + +G GLL Sbjct: 60 TYMDKHGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQ 119 Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSEC---TVE 195 G KW + RK + P F +VL SF+ +FNA + +V + D +S+ + Sbjct: 120 GSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGE-KDVLSDLIRWSFA 178 Query: 196 ILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLL 255 I +T +G + D FE A++K + LR ++ F + +N K++ Sbjct: 179 IATQTTLGTDVTKDD--NFEND-AILKTYQSM--------LRLTIINIFVPFVQN--KIV 225 Query: 256 DIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXX 315 + GL R+++ A K +N+ + S P ++ +S LK Sbjct: 226 SKLFGLE---WLRRRDASAINKMINNILDKKLNSNPE----------NYCESE-LKTVIH 271 Query: 316 XXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGI 375 + ++ ++L E S +A FE T + L+M Sbjct: 272 RAIELFRNDEMSLMELGAECSSMVLA-------------AFETSAHTVYYALVLLAMFPE 318 Query: 376 HQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEI 434 HQ++ V E+ + F VT D ++ YL+R L ETLRL P VP +R+ +++ Sbjct: 319 HQEM---VFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRETLEDL 375 Query: 435 TLPSNGKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAG 493 L SNG IP G T+ I + R D + +F+P+NFLPE+ +RH YAF+PFS G Sbjct: 376 RL-SNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFSKG 434 Query: 494 PRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 R+C+G +Y ++ K+ L ILRN+++ + + + +++K A+ Q+ + R Sbjct: 435 KRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQLAFERR 491 >UniRef50_Q5XM61 Cluster: Cytochrome P450; n=9; Pancrustacea|Rep: Cytochrome P450 - Anopheles gambiae (African malaria mosquito) Length = 147 Score = 149 bits (362), Expect = 1e-34 Identities = 70/139 (50%), Positives = 99/139 (71%), Gaps = 5/139 (3%) Query: 321 GQKKRLAFLDLLLESSQSGVA---ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 377 G++KRLAFLDLLL+S+ +G ++DE+++E+VDT MFEGHDTT AG S+ L ++ +H Sbjct: 11 GRRKRLAFLDLLLQSATTGTGSPLLTDEDVREEVDTFMFEGHDTTTAGMSWALFLLALHP 70 Query: 378 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 437 ++Q++V +E+D IFG SDRP T QD M+ LERCL ETLRLYP V R ++++TL Sbjct: 71 EVQERVHQEIDSIFGGSDRPATMQDLTAMRLLERCLKETLRLYPSVAFFGRTTSKDVTL- 129 Query: 438 SNGKKIPAGTTLVIATYKL 456 G +PAGT + I Y + Sbjct: 130 -GGYHVPAGTIVGIHAYNV 147 >UniRef50_Q6PH32 Cluster: Cytochrome P450, family 4; n=7; Clupeocephala|Rep: Cytochrome P450, family 4 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 458 Score = 149 bits (361), Expect = 2e-34 Identities = 73/174 (41%), Positives = 113/174 (64%), Gaps = 3/174 (1%) Query: 323 KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 ++ L FLD+LL + + +SDE+I+ +VDT MFEGHDTTA+G S+ + + + Q+ Sbjct: 281 RRYLDFLDILLSARDEHQQGLSDEDIRAEVDTFMFEGHDTTASGISWIFYNLACNPEHQE 340 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 K +E+ Q D + ++D ++ Y C+ E+LRL+PPVP I+R++ + +T +G+ Sbjct: 341 KCRQEIQQALDGKDT-LEWEDLNKIPYTTMCIKESLRLHPPVPGISRKLTKPLTF-FDGR 398 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495 +P G T+ ++ Y +H V+ NP KFDP FLPE +ANR +AFVPFSAGPR Sbjct: 399 TVPEGCTIGVSIYGIHMNSTVWENPYKFDPLRFLPENAANRSPHAFVPFSAGPR 452 Score = 111 bits (268), Expect = 4e-23 Identities = 59/186 (31%), Positives = 103/186 (55%), Gaps = 6/186 (3%) Query: 91 IWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149 +W GP L V ++ P + IL++ D Y+FF PWLG+GLL+STGQKW HR+L+ Sbjct: 83 LWFGPSLAVLNIHHPSYAKTILTTTEPKDDYA-YKFFIPWLGDGLLVSTGQKWFRHRRLL 141 Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVSK 206 P FH +VLK ++ L + +++ ++DK + + +F+ ++S T++ +++ A + Sbjct: 142 TPGFHYDVLKPYVKLISDSTKVMLDKWEVHSRSEESFELFKHVSLMTLDSIMKCAFSCNS 201 Query: 207 STQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKV 265 + Q SG Y AV +C +++LR +F + + K I H T +V Sbjct: 202 NCQTDSGTNPYIQAVFDLCHLVNLRFRVFPYHSKAIFHLSPHGYRFRKAASIAHNHTAEV 261 Query: 266 IKRKKE 271 I+++KE Sbjct: 262 IRKRKE 267 >UniRef50_Q8WQN5 Cluster: Cytochrome P450 CYP4H14; n=22; Endopterygota|Rep: Cytochrome P450 CYP4H14 - Anopheles gambiae (African malaria mosquito) Length = 151 Score = 149 bits (361), Expect = 2e-34 Identities = 66/153 (43%), Positives = 102/153 (66%), Gaps = 4/153 (2%) Query: 350 QVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRP--VTFQDTLEMK 407 +VDT MFEGHDTT +G SF + + + D+Q++V EE+ I G + +T+Q+ E K Sbjct: 1 EVDTFMFEGHDTTTSGISFTIYELARNPDVQERVYEEIVSILGKDHKTAELTYQNLQEFK 60 Query: 408 YLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPN 467 YL+ + E LR+YPPV II R + +++ L NG +PAG +++ Y +HR P++YPNPN Sbjct: 61 YLDLVVKEGLRMYPPVGIIGRALVEDLEL--NGTTVPAGQNVLVPIYVIHRNPEIYPNPN 118 Query: 468 KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +FDP F + + R + ++PFSAGPR+C+G+ Sbjct: 119 QFDPSRFAEDAESKRGPFDYLPFSAGPRNCIGQ 151 >UniRef50_Q095M8 Cluster: Cytochrome P450 4A5; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Cytochrome P450 4A5 - Stigmatella aurantiaca DW4/3-1 Length = 374 Score = 148 bits (358), Expect = 4e-34 Identities = 76/228 (33%), Positives = 129/228 (56%), Gaps = 4/228 (1%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 +K L + + ++G +SDE+++ ++ + GHDTTA G +F ++ H + + Sbjct: 151 RKDLLAMYMSAVDEETGEGMSDEQLRHELMNLFLAGHDTTANGLAFTFYLLSKHPEALKR 210 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 V EE D + G+ R VT +D ++ Y E LR+YPP ++R +E L N Sbjct: 211 VDEERDAVLGNG-RMVTNEDLPQLNYARWSFEEALRIYPPTFAMSRTSVRE--LKHNDYV 267 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 IPAG+ + + + LHR P ++PNP+ F+P+ F PERS RH +A++PF AGPR C+G Sbjct: 268 IPAGSNIFVCQWALHRNPRLWPNPDHFEPERFSPERSEGRHRFAYLPFGAGPRICIGAHL 327 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 A + ++I++ +L+ FR+ S+ + +L A + + G +RL R Sbjct: 328 ARTEAQMIIAMLLQRFRLNSE-PGYEPRLVARLFVTAEPGISMRLSRR 374 >UniRef50_Q5V5P9 Cluster: Cytochrome P450; n=3; Halobacteriaceae|Rep: Cytochrome P450 - Haloarcula marismortui (Halobacterium marismortui) Length = 445 Score = 148 bits (358), Expect = 4e-34 Identities = 76/223 (34%), Positives = 131/223 (58%), Gaps = 6/223 (2%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 FL +LL + G S E++++++ T++ GHDTTA ++ ++ H +++ +V EEL Sbjct: 229 FLSVLLRARDDGNQ-SPEQLRDEMMTMLLAGHDTTALTLTYTWFLLSEHPEVEQRVHEEL 287 Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447 D + GD DRP + E+ YLE + E +RLYPPV I R+ +++TL +G ++ AGT Sbjct: 288 DDVIGD-DRP-GMEHVRELDYLEWVIQEAMRLYPPVYTIFREPTEDVTL--SGYEVEAGT 343 Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507 TL++ + +HR Y +P FDP+ + PER++ R +A+ PF GPR C+G+ AML+ Sbjct: 344 TLMVPQWGVHRSERFYDDPETFDPERWKPERASERPRFAYFPFGGGPRHCIGKHLAMLEA 403 Query: 508 KVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 ++I +T +R + E+ +L + + +R+Q R Sbjct: 404 QLITATTASQYR-LEFQGETPLELLPSLTAHPRQKMSMRVQER 445 Score = 52.4 bits (120), Expect = 3e-05 Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 3/124 (2%) Query: 88 VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR--FFKPWLGNGLLISTGQKWRSH 145 V + +GP V L DP +E +L S + +++ LG+GLL+S G+ W Sbjct: 38 VARFDMGPMDTVMLCDPTAIERVLVSEADRFRKPDFQGDALGDLLGDGLLLSEGETWEQQ 97 Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVS 205 RKL P F + L D ++ + D M+ T++++L+ MGV Sbjct: 98 RKLANPAFSMARLSGMADRITGHAEDRIADW-SHGDVIDAEQSMTRVTLDVILDLMMGVE 156 Query: 206 KSTQ 209 S Q Sbjct: 157 LSEQ 160 >UniRef50_A6GGL1 Cluster: Cytochrome P450 family protein; n=1; Plesiocystis pacifica SIR-1|Rep: Cytochrome P450 family protein - Plesiocystis pacifica SIR-1 Length = 454 Score = 147 bits (356), Expect = 8e-34 Identities = 73/224 (32%), Positives = 135/224 (60%), Gaps = 7/224 (3%) Query: 329 LDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 LD+L+ + +G + ++++++ T++ GH+TT+ S+ ++ H + ++ E Sbjct: 224 LDMLMAARDEDTGEGMDARQLRDELMTLVVAGHETTSNALSWTWYLLSQHPEHVQRLRAE 283 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 +D++ GD R T +D ++++ ER L E++R+YPPV + R+ ++ + + G ++P G Sbjct: 284 VDEVLGD--RLPTPEDLAKLEHTERVLKESMRVYPPVWAVEREPSEAVEV--GGYRLPKG 339 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 T + I+ Y LHR P +P+P +FDPD F PERSA R YA++PF AGPR C+G +A+ + Sbjct: 340 TMIGISPYVLHRDPQHWPDPERFDPDRFTPERSAGRPRYAYLPFGAGPRVCIGAGFALTE 399 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 K IL+ ++R F + + ++ I L+ G ++RL+ R Sbjct: 400 AKAILAMLVRRFD-LERVPGQAVHMEPGITLRPKHGLRMRLRVR 442 Score = 57.6 bits (133), Expect = 8e-07 Identities = 40/132 (30%), Positives = 64/132 (48%), Gaps = 5/132 (3%) Query: 84 DHESVVKIWIGPRLLVFLYDPRDV-EVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKW 142 DH V+ GP V L D DV +V+++ K++ Y K LG GL+ S G W Sbjct: 30 DHGDHVRFRFGPFSYVSLRDLEDVRKVLVTDAQRYTKSKVYTALKLLLGEGLVTSEGAMW 89 Query: 143 RSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK--KEASNFDCHDYMSECTVEILLET 200 + RKL +P F + SF + A +R + ++ + + + D HD M T+ I+ T Sbjct: 90 QRQRKLSSPAFRPRAVASFTEAMGACTRDLGERWRGLGDGAELDVHDEMMRLTLRIVGMT 149 Query: 201 AMGVSKSTQDQS 212 VSK + ++ Sbjct: 150 L--VSKDLEGEA 159 >UniRef50_Q9VG40 Cluster: Probable cytochrome P450 313a4; n=3; Sophophora|Rep: Probable cytochrome P450 313a4 - Drosophila melanogaster (Fruit fly) Length = 478 Score = 147 bits (356), Expect = 8e-34 Identities = 74/225 (32%), Positives = 135/225 (60%), Gaps = 4/225 (1%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 FL+L+ + + GV + + ++++ + I+F +TTA + L ++ + + Q++ EE+ Sbjct: 255 FLNLVTDLMRRGV-FTLKNVEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEI 313 Query: 388 DQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 IF ++ D V++ DT +M YL+ L E++R+ PPVP+++RQ +Q++ L SNG +P G Sbjct: 314 KTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPPVPVVSRQTSQDLKL-SNGIVVPKG 372 Query: 447 TTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505 + I Y +HR ++ P+ F+PD+FLP ++H YA++PF+ G R+C+G +YA++ Sbjct: 373 VQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDKHPYAYIPFTKGIRNCIGWRYALI 432 Query: 506 KLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 KV L+ +LRN+R + + DI +K + LQ R Sbjct: 433 SAKVTLAKLLRNYRFKTSFPFENLYFVEDITMKLKSVPLLELQKR 477 Score = 62.9 bits (146), Expect = 2e-08 Identities = 53/197 (26%), Positives = 86/197 (43%), Gaps = 7/197 (3%) Query: 20 LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79 L + L + L + Y+ SRRR Y L K+ A ++ DI N Sbjct: 2 LTWTLWCGLLFLLWIYFLWSRRRFYLLTLKIPGPLGYPILGMA-HWLMRREDIL-NAFGC 59 Query: 80 SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139 D H + W+GP + + DP+ V+ I +S ++K Y+ G GL Sbjct: 60 FLD-KHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGVGLFSLKD 118 Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK--KEASNFDCHDYMSECTVEIL 197 +W HRKL+ P F VL SF+ +FN + ++D+L+ ++ D + T+ I Sbjct: 119 PRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLIPLLQSFTLGIA 178 Query: 198 LETAMGVSKSTQDQSGF 214 +T MG +D+ F Sbjct: 179 TQTTMG--SDVKDEESF 193 >UniRef50_UPI00005A2E9B Cluster: PREDICTED: similar to cytochrome P450, family 4, subfamily A, polypeptide 11; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to cytochrome P450, family 4, subfamily A, polypeptide 11 - Canis familiaris Length = 411 Score = 146 bits (354), Expect = 1e-33 Identities = 79/222 (35%), Positives = 128/222 (57%), Gaps = 27/222 (12%) Query: 323 KKRLAFLDL-LLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 K+ L FLD+ ++G +SD++++ +VDT FEGHDTTA+G S+ L + H + Q Sbjct: 169 KRHLDFLDISFFAKMENGRGLSDKDLRAEVDTFKFEGHDTTASGISWILYALATHPEHQQ 228 Query: 382 KVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 + EE+ + GD + F++ L+ M Y C+ E LRLY PVP + R++++ IT P +G Sbjct: 229 RCREEIQSLLGDG---LCFREHLDQMPYTTMCIKEALRLYLPVPTVGRELSKPITFP-DG 284 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNK-------------------FDPDNFLPERSAN 481 + +P G ++++ Y LH +V+PNP FDP F P+ A+ Sbjct: 285 RSLPRGFLVLLSFYALHHNSNVWPNPEVERKEELDHTYPGPGVPLQVFDPSRFAPD--AS 342 Query: 482 RHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 523 RH +AF+PFS G R+C+G+ +AM ++KV ++ L F + D Sbjct: 343 RHSHAFLPFSGGSRNCIGQHFAMKEMKVAVALTLLRFELAPD 384 Score = 46.4 bits (105), Expect = 0.002 Identities = 21/86 (24%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV----DKLKKEASNFDCH 186 G GLL+ G+ W HR+++ P FH ++LK ++ L + + ++ ++L + S+ + Sbjct: 71 GYGLLLLNGEIWFQHRRMLTPAFHYDILKPYVRLMVDSVQVMLVNKWEELLSQNSHLEIF 130 Query: 187 DYMSECTVEILLETAMGVSKSTQDQS 212 +++S T++ +++ A S ++ S Sbjct: 131 EHVSLMTLDTIMKCAFRPSDQAEEGS 156 >UniRef50_UPI0000F21E21 Cluster: PREDICTED: similar to cytochrome P450 CYP4F13; n=1; Danio rerio|Rep: PREDICTED: similar to cytochrome P450 CYP4F13 - Danio rerio Length = 328 Score = 146 bits (353), Expect = 2e-33 Identities = 67/184 (36%), Positives = 112/184 (60%), Gaps = 2/184 (1%) Query: 339 GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD-RP 397 G +++EEIK D MF GHDTTA+ S+ + ++QD Q++ E+ + D D Sbjct: 116 GEGLTNEEIKAHADMFMFAGHDTTASALSWIFYNLAMNQDYQERCRAEVRDLLADRDTHT 175 Query: 398 VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLH 457 + ++D ++ + C+ E+LRL+ PV + R +Q + P + IP G +I+ Y +H Sbjct: 176 IGWEDLSQLTFTTMCIKESLRLHSPVLALTRYYSQNMKTPGDCV-IPHGCLCLISIYGVH 234 Query: 458 RRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRN 517 R P V+P+P FDP F P S +R +AF+PFSAGPR+C+G+ +AM ++KV+++ L Sbjct: 235 RNPQVWPDPLVFDPTRFDPHNSDSRSPHAFIPFSAGPRNCIGQNFAMAEMKVVVALTLAR 294 Query: 518 FRVI 521 F+++ Sbjct: 295 FKIL 298 Score = 70.1 bits (164), Expect = 1e-10 Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 3/86 (3%) Query: 92 WIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 148 ++GP +V L+ P + +L++ I + Y F KPWLGN LL+ +GQ+W HR+L Sbjct: 28 FLGPFYNMVRLFHPDYIRSLLTASASITLKDRIFYGFMKPWLGNCLLLQSGQEWSRHRRL 87 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVD 174 + P FH ++LK ++ +FN ++ + D Sbjct: 88 LTPAFHFDILKKYVHIFNQSTNIMHD 113 >UniRef50_UPI0000D55FA3 Cluster: PREDICTED: similar to Cytochrome P450 4g15 (CYPIVG15); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4g15 (CYPIVG15) - Tribolium castaneum Length = 193 Score = 145 bits (351), Expect = 3e-33 Identities = 74/174 (42%), Positives = 110/174 (63%), Gaps = 3/174 (1%) Query: 354 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 413 ++F G + A + L M+ IH +IQ+K+ EEL IFG+SDR + F+D ++ YL+R + Sbjct: 1 MVFTGSGSLAITECYVLLMLAIHPEIQEKIYEELLTIFGNSDRDLCFKDLSKLCYLDRVI 60 Query: 414 METLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDN 473 ETLRL+P P IAR ++ +I + IP GT +I L R +++ P +FDPD Sbjct: 61 KETLRLFPIAPYIARLLDSDIHMEKY--VIPKGTFALIPITYLQRNSNLWSEPLRFDPDR 118 Query: 474 FLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKES 527 FLPE+ A R ++PFS G R+C+G KYA + LK L+TILR ++ +S L+ES Sbjct: 119 FLPEQVATRERCVYLPFSYGSRNCIGLKYAEISLKATLATILRKYKYVS-LRES 171 >UniRef50_A7RNE6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 498 Score = 145 bits (351), Expect = 3e-33 Identities = 72/192 (37%), Positives = 108/192 (56%), Gaps = 2/192 (1%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 L +++ G+ + EE+ + T G +TTA SF L +G+H DI KV+EE+D Sbjct: 280 LSTIMKLELQGLELDIEELLDDFVTFFIAGQETTANQLSFALLEIGLHPDITHKVVEEVD 339 Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448 ++ G V + D + Y+ + L ETLR YPP + R +EITL NG IPAGT Sbjct: 340 KVIGSHVDFVEYDDLANLSYMTQVLKETLRKYPPAAGVIRHSPEEITL--NGHVIPAGTG 397 Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508 + + Y H P + +P FDP+ F E + N + F+PFS GPRSC+G+ +A + K Sbjct: 398 IGLNIYGAHHNPTNWKDPEVFDPERFNAENAPNIKPFTFLPFSLGPRSCIGQHFAQFEAK 457 Query: 509 VILSTILRNFRV 520 V+L+ L+ FR+ Sbjct: 458 VLLARFLQKFRI 469 >UniRef50_A7SJV6 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 512 Score = 144 bits (350), Expect = 4e-33 Identities = 73/210 (34%), Positives = 117/210 (55%), Gaps = 3/210 (1%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 +SD+EI Q T + G++TT+ +F ++ ++ D QD++IEE+D++ + Sbjct: 305 LSDDEIVAQCFTFILAGYETTSNTMAFTSYLLALNPDKQDRLIEEIDEVAATVGDNFDYD 364 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 L M+YLE + E LRLYPP R NQ T+ NG+ P G ++I + +HR P+ Sbjct: 365 TVLGMEYLEMVVQEALRLYPPGFRFGRTCNQSCTI--NGQFFPKGCIVLIPVFAMHRDPE 422 Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 520 ++P P KF P+ F E RH YA +PF GPR+C+G ++A+L+ K+ L ILR +R+ Sbjct: 423 IWPEPEKFQPERFTAEAKQARHPYAHLPFGGGPRNCIGMRFALLEAKMALVYILRYYRLE 482 Query: 521 ISDLKESDFKLQADIILKRAEGFQVRLQPR 550 E +LQ I + G +++ R Sbjct: 483 RCPETEVPVQLQGTITISPKHGIYLKITKR 512 Score = 44.4 bits (100), Expect = 0.008 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 5/123 (4%) Query: 92 WIGPRLLVFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149 ++G R + + DP + IL ++++ P LL WR R I Sbjct: 84 YMGTRAAILVADPEMAKQILVKEFDKFVNRPIVQSAQTPPTDKTLLSLQDDDWRRLRHTI 143 Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVSK 206 PTF LK + L N + R +V+KL K+ + D + T+E ++ TA G+ Sbjct: 144 TPTFSAVKLKQVLPLINESCRILVEKLGEACKDGKSVDVLRSYGKFTMETIVTTAFGIDC 203 Query: 207 STQ 209 TQ Sbjct: 204 QTQ 206 >UniRef50_UPI0000D56428 Cluster: PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1) - Tribolium castaneum Length = 713 Score = 144 bits (349), Expect = 5e-33 Identities = 72/174 (41%), Positives = 106/174 (60%), Gaps = 7/174 (4%) Query: 349 EQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKY 408 E+ + F G +T+ S L ++G+ IQ+K+ E+DQ+FG S T + + Y Sbjct: 269 EEAQIMFFVGTETSGVAISSVLLILGMFPQIQEKIFIEIDQVFG-STTGSTLDEINHLDY 327 Query: 409 LERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNK 468 LER + ETLRL PP+P + R +++ + L PAG+ +++ +HRR D +P P K Sbjct: 328 LERVIKETLRLLPPIPFVMRSLDENLKLSCG--TFPAGSRVIVPIMMVHRREDFWPEPLK 385 Query: 469 FDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 522 FDPD FL ER + ++PFS G R+C+G KYAML +KVIL+TILR +RV S Sbjct: 386 FDPDRFLEERPSG----TYIPFSYGTRNCLGYKYAMLSMKVILATILRKYRVKS 435 Score = 79.8 bits (188), Expect = 2e-13 Identities = 51/165 (30%), Positives = 78/165 (47%), Gaps = 4/165 (2%) Query: 85 HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144 + VVKIW GP L V +P D++VIL+ H +DK E Y + L + W+ Sbjct: 63 YPKVVKIWFGPWLYVSTTEPSDLKVILTHH--LDKGEFYELMSEYFRRALAAAPVDLWKK 120 Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGV 204 HRK I PTF+ +L +FI F + +V L+K S+ D + +CT++ ET V Sbjct: 121 HRKNINPTFNTTILNTFIGAFAKQAEILVKNLEKYQSDEDIFPIVWKCTLDSACETLADV 180 Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAK 249 D V ++ +IL R ++L+KF+ K Sbjct: 181 DPIFIDTEA--CLRRVFRIEEILLERFFNPLCHLNILWKFSPLRK 223 >UniRef50_Q6SPQ5 Cluster: CYP342A1; n=1; Nereis virens|Rep: CYP342A1 - Nereis virens (Sandworm) Length = 508 Score = 144 bits (349), Expect = 5e-33 Identities = 69/193 (35%), Positives = 119/193 (61%), Gaps = 5/193 (2%) Query: 332 LLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIF 391 LLE V + D EI+++VDT MFEGHDTTA+G S+ L + H ++Q++ +E+ ++ Sbjct: 317 LLEMRTEKVCL-DREIRDEVDTFMFEGHDTTASGISWILYELSGHPEVQEQAGQEVIRVI 375 Query: 392 G-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450 G SD + + D + YL +C+ E +R++PPVP I RQ++Q+I + NG IP T Sbjct: 376 GSQSDGTIEWSDLSRLPYLSQCIKEAMRVHPPVPFIGRQLSQDIII--NGCTIPKDTICE 433 Query: 451 IATYKLHRRPDVYPNPN-KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKV 509 ++ Y +H P+V+ + +F P+ F P+ ++ + ++PFSAG R+C+G+ +A+ + KV Sbjct: 434 VSIYGVHHNPEVWGKDHMEFKPERFHPDNMKDKDAFDYIPFSAGSRNCIGQNFALNEEKV 493 Query: 510 ILSTILRNFRVIS 522 ++ R+ S Sbjct: 494 VIRQGFAEVRITS 506 Score = 48.8 bits (111), Expect = 4e-04 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 7/99 (7%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGP-RLLVFLYDPRDVE---VILSSHVY 116 N +F G ++F + K Y + + W+GP ++ L P + ++ + V+ Sbjct: 76 NLSDFPGPGPEVFGWVQGKVNQY--KKFYQFWVGPFSPMISLCHPETSQNHPEVIRTKVH 133 Query: 117 IDKAEEYRFF-KPWLGNGLLISTGQKWRSHRKLIAPTFH 154 + + K WLG+GLL+S+G KW +R+L+ P FH Sbjct: 134 LHRIWPVMLLLKEWLGDGLLLSSGSKWFRNRRLLTPAFH 172 >UniRef50_UPI0000E4657A Cluster: PREDICTED: similar to cytochrome P450 3A27; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cytochrome P450 3A27 - Strongylocentrotus purpuratus Length = 460 Score = 144 bits (348), Expect = 7e-33 Identities = 117/434 (26%), Positives = 200/434 (46%), Gaps = 38/434 (8%) Query: 130 LGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVD---KLKKEASNFDCH 186 L G+L + ++WR R L++P+F LKS + L + +VD K ++E +C Sbjct: 48 LAGGMLAAKDERWRKLRSLLSPSFTSVKLKSMVPLMRECAEVLVDIFTKREEEGKTIECK 107 Query: 187 DYMSECTVEILLETAMGV---SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFK 243 + ++++ A G+ S++ QD+ +YA I + T +LF Sbjct: 108 ELYGPYAMDVIGSCAFGLRVNSQTNQDEPFIKYAKR------IFNFNVTNPAFLISMLFP 161 Query: 244 FTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLS 303 +T N KL G K I E+F G + + + TGK +E + Sbjct: 162 WTAPIFNFFKL-----GSVPKDI----EQFFLGVFEKAIADRQANGD--TGKSDFLELMM 210 Query: 304 FGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESS---QSGVAISDEEIKEQVDTIMFEGHD 360 S K + +A DL E+S + A++ +EI T + G++ Sbjct: 211 ----SAHKEDDDVNIMNDAEDDIA--DLAQETSWKPKQKTALNRQEIIGNSITFLLAGYE 264 Query: 361 TTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLY 420 T++ F ++ +Q +QD ++ E+ ++ S VTF+ +M+YL +ME +R+Y Sbjct: 265 TSSTALGFVSYLLATNQHVQDLLVAEVKEM-APSQSDVTFETVTKMEYLNMVIMEAMRIY 323 Query: 421 PPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSA 480 PP ++ R N+EIT N I G + I + L D++P+P FDP+ F +R Sbjct: 324 PPGEVLERVCNKEITY--NNITIKKGQYIFIPIWNLQHDSDLWPDPETFDPERFSKDRRG 381 Query: 481 NRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDF--KLQADIILK 538 N H ++PF GP +C+G ++AML++KV + IL+ FR E++ KL L Sbjct: 382 NNHPCGWLPFGIGPHTCIGVRFAMLEIKVAMVCILQKFR-FDTCPETEIPPKLGNLSFLT 440 Query: 539 RAEGFQVRLQPRKR 552 G +R+ P R Sbjct: 441 PPNGITLRITPHSR 454 >UniRef50_Q06GC7 Cluster: Cytochrome P450; n=1; Rhodococcus sp. NS1|Rep: Cytochrome P450 - Rhodococcus sp. NS1 Length = 497 Score = 142 bits (344), Expect = 2e-32 Identities = 73/216 (33%), Positives = 126/216 (58%), Gaps = 7/216 (3%) Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396 ++G +SD+ I+ QV T + GH+TTA SF L + ++ +I ++ EE++Q+ G Sbjct: 284 ETGEMMSDQSIRNQVLTFLIAGHETTAGLLSFALHYLSLNPEIVERAREEIEQVLGTDGA 343 Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456 PV F+ +++Y+ R + ETLRL+P P R+ Q TL +G I G T+++ L Sbjct: 344 PVRFEQVAKLRYVRRIIDETLRLWPSGPAFFRKARQATTL--DGYPIRKGETILVVLLAL 401 Query: 457 HRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515 HR P ++ +P +FDPD FLP R +A+ PF G R+C+GR++A+ + + L+ IL Sbjct: 402 HRDPALWGEDPERFDPDRFLPAAVRARPAHAYKPFGVGARACIGRQFALHEAVLALAQIL 461 Query: 516 RNFRVISDLKESDFKLQADIILK-RAEGFQVRLQPR 550 F ++ +D++L + +L R E ++ ++PR Sbjct: 462 TRFDIV---PTADYELTVEELLTIRPENLKLAMRPR 494 >UniRef50_Q16L53 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 488 Score = 142 bits (343), Expect = 3e-32 Identities = 79/214 (36%), Positives = 127/214 (59%), Gaps = 9/214 (4%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 F+D LL + G + S+ +I V T++ G+DT+ ++ +G++ IQ+KV E+ Sbjct: 276 FVDQLL---RLGNSFSETDIIHNVFTMIIAGNDTSGQLMAYACLFLGMYPHIQEKVHAEI 332 Query: 388 DQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 +I + P++ + + Y E L E LRL P P I RQ ITL +IPAG Sbjct: 333 VEIIPRHHNEPISPEKLKSLAYTEMFLNECLRLCPTAPNIVRQNMAPITLDET--RIPAG 390 Query: 447 TTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505 L I+ + HRR D++ P+ ++FDPD F ERSA RH +AF+PFS G R+C+G +YAM+ Sbjct: 391 NLLAISLFAYHRRKDIWGPDADEFDPDRFSAERSAGRHPFAFLPFSGGSRNCIGWRYAMI 450 Query: 506 KLKVILSTILRNFRVISDLKESD--FKLQADIIL 537 +K++L +LR F++ +D++ D F+ A ++L Sbjct: 451 SMKLMLVYLLREFKIKTDIRHQDMAFRFNAALVL 484 Score = 88.6 bits (210), Expect = 4e-16 Identities = 49/184 (26%), Positives = 97/184 (52%), Gaps = 5/184 (2%) Query: 90 KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149 K+W+GP + + + P V+++L+ ++K YRF + + GLL++ + W+ HRK++ Sbjct: 77 KVWLGPVVCLGVCHPDLVQIVLTHPDCLEKPFIYRFIR--INRGLLVAEAELWKRHRKVL 134 Query: 150 APTFHLNVLKSFIDLF-NANSRAVVD-KLKKEASNFDCHDYMSECTVEILLETAMGVSKS 207 F+L +L FI +F SR V D K K+ FD + + CT+E++ ET++G Sbjct: 135 NSAFNLRILHGFIPIFEKCCSRMVSDLKQMKDGETFDVMRFTARCTLEMVFETSLGTGCL 194 Query: 208 TQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIK 267 +S + + +I R + L + +F+ T +K +T+ L + + K+++ Sbjct: 195 PPSESDC-LIRHIKRFFNIASSRFLNVHLHYEPIFRLTQRSKKETESLHYCNTVVKQLLT 253 Query: 268 RKKE 271 K++ Sbjct: 254 EKRQ 257 >UniRef50_Q179B9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 506 Score = 141 bits (342), Expect = 4e-32 Identities = 74/225 (32%), Positives = 131/225 (58%), Gaps = 5/225 (2%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 +D LL S G +D +I++ V ++ DTT+ ++ + + DIQ+++ EL Sbjct: 276 VDQLLGVSHDGRQFNDIQIRDNVYAVITGATDTTSLATAHACLFLSFYPDIQERLHAELA 335 Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448 ++F + T ++ ++ YL+ + E R VP +AR+ EI + +G K+P G Sbjct: 336 EVFPGNIADYTPENIKKLTYLDMFINEVQRHCTVVPYVARENTAEIEI--DGVKVPPGNI 393 Query: 449 LVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507 +++ Y +H+RPD++ P+ KFDP+NF ER +RH AF+P+SAG ++C+G +YA+ + Sbjct: 394 FIMSLYAMHKRPDIWGPDAEKFDPENFTEERIKDRHPAAFLPYSAGSKNCLGWRYAIFGM 453 Query: 508 KVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552 K+I+ ++RNF S +K D + + D+ LK FQ +Q +KR Sbjct: 454 KLIMIHLVRNFHFSSKIKHEDMQFRHDLTLKLP--FQHLVQLKKR 496 Score = 51.2 bits (117), Expect = 7e-05 Identities = 55/255 (21%), Positives = 103/255 (40%), Gaps = 11/255 (4%) Query: 20 LFYVLLVPAVILWYAYWRMSRRRLYELADKL-NXXXXXXXXXNALEFVGGSADIFRNIVQ 78 +F+ + LWY +R ++ ADK + NAL + + D+ R Sbjct: 5 VFFGTIATLGTLWYWTYRWQ----FKFADKWPSVRPRYAIVGNALIMLWKN-DVQRFQEI 59 Query: 79 KSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST 138 K + + ++ W GP++ + P V ILSS +++ YRF G+ + Sbjct: 60 KRVFSECDRILTAWAGPKMFLITSHPDIVHQILSSPDCLERPFLYRF--AGFTQGIFTAK 117 Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEI 196 W+ +RK + TF+ ++ F+ F + L + + + Y + C +E+ Sbjct: 118 LPVWKDNRKRLNSTFNQRIVHGFVPYFVKCCEKMTKSLLECADGETVNIQKYTAVCALEM 177 Query: 197 LLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLD 256 T +G Q E+ + + R + DL+++ T + K + Sbjct: 178 AAGTTLGGDVLQQGDGKEEFKRGLDLAFNGASRRMVTVPFYSDLIYQMTHHYKELMEGRR 237 Query: 257 II-HGLTKKVIKRKK 270 II TK +I+RKK Sbjct: 238 IICDFFTKLLIERKK 252 >UniRef50_A7SXR0 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 481 Score = 141 bits (342), Expect = 4e-32 Identities = 75/219 (34%), Positives = 123/219 (56%), Gaps = 4/219 (1%) Query: 321 GQKKRLAFLDL-LLESSQSGVA-ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378 G+KK L L L E + GV ++D+E+ Q T + G +TT + ++ H D Sbjct: 251 GRKKDLVTLMLEAREDTVDGVPRLNDQELAAQSLTFLLAGFETTTNTLANTAYLLARHPD 310 Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438 +QDK+I+ELD + ++ + ++ YL+R + E+LRLYPP +I R+ ++E T+ Sbjct: 311 VQDKLIQELDLAGSNRGNSPLYEYSQKIDYLDRVINESLRLYPPGYLIIRRYDEECTI-- 368 Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 G P G + I Y LHR P V+ P+ FDP++F E + RH Y+F+PF GPR C+ Sbjct: 369 QGVHFPRGVDVNIPVYILHRDPAVWERPDDFDPEHFSHEANEKRHPYSFIPFGMGPRQCI 428 Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIIL 537 G ++A++++K+ L IL ++ S + D +IL Sbjct: 429 GMRFALMEIKIALVNILEKYKFCSSEETQDLLEHRAVIL 467 Score = 51.6 bits (118), Expect = 5e-05 Identities = 44/199 (22%), Positives = 88/199 (44%), Gaps = 18/199 (9%) Query: 88 VVKIWIGPRLLVFLYDPRDVE--VILSSHVYIDKAEEYRFFKPW--LGNGLLISTGQKWR 143 V K++IG + + DP V+ VI H + ++ F KP + +G+ + G W+ Sbjct: 65 VHKMFIGRAPAIVVSDPEIVKQIVIKEFHKFPNRP---LFIKPNPPMDSGMFLGQGALWK 121 Query: 144 SHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMG 203 R + PTF LK + + ++ + + + + + DC + S ++++ +A G Sbjct: 122 RIRTTLTPTFSTAKLKQIVPIIDSRKWPLSPQQVERSESTDCVNLFSLFALDVITISAFG 181 Query: 204 VSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLL---DIIH 259 V Q D Y +A T IW+R +F F++Y +L D Sbjct: 182 VETDIQTDPDSSFYKLAKKAF-------RTPIWVRAFSMFPFSEYLSKYVHVLPNIDYFL 234 Query: 260 GLTKKVIKRKKEEFASGKK 278 + +++++K+ + G+K Sbjct: 235 KIALSMVEQRKKHGSQGRK 253 >UniRef50_Q8UF31 Cluster: Cytochrome P450; n=1; Agrobacterium tumefaciens str. C58|Rep: Cytochrome P450 - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 464 Score = 140 bits (340), Expect = 7e-32 Identities = 74/230 (32%), Positives = 126/230 (54%), Gaps = 7/230 (3%) Query: 329 LDLLLESS--QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 + +LLE+ ++G +SDEEI + + T + GH+TTA G ++ ++ + + + K +EE Sbjct: 239 VSMLLEAKDPETGRMMSDEEIIDNLLTFITAGHETTALGLAWTFHLLSQNPETERKAVEE 298 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 ++ + G PV + + Y+ + E +RLYPP P+I R Q+ L + IPAG Sbjct: 299 IEAVTGGE--PVAAEHIANLAYVRQVFSEAMRLYPPAPVITRTALQDFRLGEHD--IPAG 354 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 T L + Y +HR ++ P +FDP F PE+ RH YA++PF AGPR C+G +AM++ Sbjct: 355 TVLYVPIYAVHRHTALWDEPERFDPSRFEPEKVKARHRYAYMPFGAGPRVCIGNAFAMME 414 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRMAKA 556 IL+ IL+ + + S L + L+ E +++ R+ + A Sbjct: 415 AVAILAVILQKNHLENRTMASAEPLMR-VTLRPQERLMMKITQRQNKSPA 463 Score = 42.3 bits (95), Expect = 0.032 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 7/138 (5%) Query: 86 ESVVKIWIGPRLLVFLYDPRDV-EVILSSHVYIDKAEEYR-FFKPWLGNGLLISTGQKWR 143 E V +G + V L DP + E ++ + + K E+ R P LG GLL + G W+ Sbjct: 46 EPAVFTRLGGVMRVHLADPVLIHEALVKNAALLGKGEDVRRALGPALGQGLLTADGDHWK 105 Query: 144 SHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA-SNFDCHDYMSECTVEILLETAM 202 R+ +A F L + + +R + + + ++ D M T +I++ET M Sbjct: 106 WQRQSVAAAFRHEKLLELLPVMIETARRTQKRWRSSSTADIDIGHEMMRTTFDIIVETMM 165 Query: 203 ----GVSKSTQDQSGFEY 216 G+ + +QS +Y Sbjct: 166 SGGYGIDIARVEQSITDY 183 >UniRef50_Q8T632 Cluster: Cytochrome P450 CYP6P3; n=42; Diptera|Rep: Cytochrome P450 CYP6P3 - Anopheles gambiae (African malaria mosquito) Length = 509 Score = 140 bits (340), Expect = 7e-32 Identities = 64/180 (35%), Positives = 103/180 (57%) Query: 340 VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVT 399 V ++ E+ Q G +T++ SF L + + DIQ+++ EE+++ ++ VT Sbjct: 297 VGMTQNELAAQAFVFFLAGFETSSTTQSFCLYELAKNPDIQERLREEINRAIAENGGEVT 356 Query: 400 FQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 459 + + +KYL+ + ETLR YPPV + R + + +P IP T + I Y + R Sbjct: 357 YDVVMNIKYLDNVIDETLRKYPPVESLTRVPSVDYLIPGTKHVIPKRTLVQIPAYAIQRD 416 Query: 460 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519 PD YP+P +F+PD FLPE RH + F+PF GPR C+G ++ +++ KV L T+LR FR Sbjct: 417 PDHYPDPERFNPDRFLPEEVKKRHPFTFIPFGEGPRICIGLRFGLMQTKVGLITLLRKFR 476 >UniRef50_Q86GR1 Cluster: Cytochrome P450 CYPm3r5; n=12; Culicidae|Rep: Cytochrome P450 CYPm3r5 - Anopheles gambiae (African malaria mosquito) Length = 519 Score = 140 bits (340), Expect = 7e-32 Identities = 75/236 (31%), Positives = 127/236 (53%), Gaps = 13/236 (5%) Query: 324 KRLAFLDLLLESSQSGVA---------ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMG 374 +R FLDLL+ +G +S +EI Q G +T+++ ++ L + Sbjct: 273 RRNDFLDLLIRLKNTGSLEGSHEIVGRLSGDEIAAQAFIFFTAGFETSSSAMTYTLYELA 332 Query: 375 IHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEI 434 ++Q+ Q K E + + D V+++ + M YL++C+ ETLR YPPV I+ R V + Sbjct: 333 LNQEAQRKARECVLEALAKHDGVVSYESSKNMLYLDQCIYETLRKYPPVAILERIVTKPY 392 Query: 435 TLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGP 494 +P + G ++I Y +H PD+YP P +DPD F PER A R A++PF GP Sbjct: 393 RIPDTSVTLHPGMKIMIPAYAIHHDPDIYPEPATYDPDRFTPERMARRDPCAYLPFGEGP 452 Query: 495 RSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD---IILKRAEGFQVRL 547 R C+G ++ M++ ++ L+ +L++F+V+ KE+D L +L G ++RL Sbjct: 453 RICIGLRFGMMQARIGLALLLKHFQVL-PCKETDVPLTYSPRAFVLTPVNGVRLRL 507 >UniRef50_Q89R90 Cluster: Blr2882 protein; n=4; Bacteria|Rep: Blr2882 protein - Bradyrhizobium japonicum Length = 1078 Score = 140 bits (339), Expect = 9e-32 Identities = 75/215 (34%), Positives = 121/215 (56%), Gaps = 4/215 (1%) Query: 338 SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG-DSDR 396 +G + D I+ Q++T + GH+TT+ S+ L + H DI K +E+D++FG D + Sbjct: 252 TGEQLDDVNIRYQINTFLIAGHETTSGLLSYTLYALLKHPDILKKAYDEVDRVFGPDVNA 311 Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456 T+Q ++ Y+ + L E LRL+PP P + T+ K+ GT + I L Sbjct: 312 KPTYQQVTQLTYITQILKEALRLWPPAPAYGISPLADETIGGGKYKLRKGTFITILVTAL 371 Query: 457 HRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515 HR P V+ PNP+ FDP+NF E A R A+ PF G R+C+GR +AM + + L IL Sbjct: 372 HRDPSVWGPNPDAFDPENFSREAEAKRPINAWKPFGNGQRACIGRGFAMHEAALALGMIL 431 Query: 516 RNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 + F++I D + L+ + +K EGF+++++PR Sbjct: 432 QRFKLI-DHQRYQMHLKETLTMK-PEGFKIKVRPR 464 >UniRef50_A7D7T8 Cluster: Cytochrome P450; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Cytochrome P450 - Halorubrum lacusprofundi ATCC 49239 Length = 469 Score = 140 bits (338), Expect = 1e-31 Identities = 71/222 (31%), Positives = 125/222 (56%), Gaps = 7/222 (3%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 L +LL + G +DE +++++ T++ GHDTTA ++ ++ H + +++V E Sbjct: 255 LSVLLRARDRGEQ-TDENLRDELVTMLLAGHDTTALALTYTFYLLSNHPEARERVAREAA 313 Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448 +D P T D EMK+ ER L E+LRLYPPV + R+ ++ L G +IP G+ Sbjct: 314 A--ATADGPPTAADAREMKFTERVLNESLRLYPPVYTLFREPKLDVKL--GGYRIPEGSA 369 Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508 L+++ + +HR P Y +P FDP + PER + R +AF PF GPR C+G+ +++L+ K Sbjct: 370 LMLSQWAIHRSPRWYDDPETFDPSRWEPERQSKRPRFAFFPFGGGPRHCIGKAFSLLEAK 429 Query: 509 VILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +IL+ + + + D + D L+ + + +R++ R Sbjct: 430 LILAEVCSRYDL--DYEGPDLSLRGSLTMHPDHPVPMRIRER 469 Score = 47.2 bits (107), Expect = 0.001 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Query: 88 VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR--FFKPWLGNGLLISTGQKWRSH 145 VV+ +GPR L +P DVE +L + + ++ LGNGLL+S G+ W Sbjct: 38 VVRFDLGPRETYMLTNPADVERVLVADAERYRKPDFGDDAIDTLLGNGLLMSEGETWERQ 97 Query: 146 RKLIAPTFH 154 R+L +P+FH Sbjct: 98 RRLASPSFH 106 >UniRef50_UPI00015B4AC4 Cluster: PREDICTED: similar to cytochrome P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 521 Score = 139 bits (337), Expect = 2e-31 Identities = 67/202 (33%), Positives = 110/202 (54%), Gaps = 5/202 (2%) Query: 324 KRLAFLDLLLESSQSGV-----AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378 KR F+DLL+E G + + I Q G++T++ +F L + ++ + Sbjct: 286 KRHDFMDLLIELKNRGTLELDNVLDENTIAAQAFVFFVAGYETSSNTIAFCLYELAVNPE 345 Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438 IQ+K ++ D +T+ +MKYL+ ++ETLR YPP P+++R+ LP Sbjct: 346 IQEKARRDIIDALDKRDSKLTYDAVQDMKYLDMVILETLRKYPPAPLLSRRCEYPYKLPG 405 Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 + ++ G +VI Y +H P YP P+KF P+ F E RH Y F+PF GPR+C+ Sbjct: 406 SDVELSKGMRVVIPIYAIHHDPKHYPEPDKFRPERFGDEEKRARHPYTFLPFGEGPRNCI 465 Query: 499 GRKYAMLKLKVILSTILRNFRV 520 G ++A+L+ KV + T LR ++V Sbjct: 466 GTRFALLQTKVGVITFLRKYQV 487 >UniRef50_Q82D73 Cluster: Putative cytochrome P450; n=2; Streptomyces avermitilis|Rep: Putative cytochrome P450 - Streptomyces avermitilis Length = 470 Score = 139 bits (337), Expect = 2e-31 Identities = 73/206 (35%), Positives = 114/206 (55%), Gaps = 4/206 (1%) Query: 346 EIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD-SDRPVTFQDTL 404 E++EQV + GH+TTA +F L ++ H + Q +V +E D++ G R T D Sbjct: 261 ELREQVLIFLLAGHETTATALAFALHLLARHPEQQRRVRDEADRVLGGPGGRAPTAADME 320 Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464 + YL L E +RLYP P+I R+ + + +G +IPAG L ++ + HR PD +P Sbjct: 321 ALPYLTMVLKEAMRLYPSAPVIGRRAVADAEV--DGVRIPAGADLFVSPWVTHRHPDYWP 378 Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDL 524 +P +FDP+ F PE A R YA+ PF GPR+C+G+ +ML+ + L+ ++R F + Sbjct: 379 DPERFDPERFTPEAEAGRPRYAWFPFGGGPRACIGQHLSMLESVLGLAVLIREFE-FEAV 437 Query: 525 KESDFKLQADIILKRAEGFQVRLQPR 550 E + L A I L + R+ PR Sbjct: 438 GEEEVPLGAGITLLAKGPARCRVIPR 463 >UniRef50_Q4U3Y5 Cluster: CYP325D1; n=1; Anopheles gambiae|Rep: CYP325D1 - Anopheles gambiae (African malaria mosquito) Length = 304 Score = 139 bits (337), Expect = 2e-31 Identities = 70/183 (38%), Positives = 112/183 (61%), Gaps = 4/183 (2%) Query: 327 AFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 A LD LL ++ G +SD EI + + +I+ G+DTTA + +H +Q K+ +E Sbjct: 125 AMLDRLLSVNEDG-PLSDTEIVQNIYSIVGAGNDTTAHSLGHTCLFLAMHPAVQRKLYQE 183 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 L +F +D P+T + ++ Y+E + E+LRL PP +AR+ +++T+ G+ IP G Sbjct: 184 LRDVFYSADEPITEEKLKQLSYMECVIKESLRLAPPGATVAREAQEDLTV--EGQLIPRG 241 Query: 447 TTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505 TT+V++ + LHRR D + + +FDPD FL ER NR AF+PF+ G R+C+G +YAM Sbjct: 242 TTVVVSLFALHRRKDFWGADAERFDPDRFLSERCKNRMGCAFMPFNTGSRNCIGSRYAMQ 301 Query: 506 KLK 508 +K Sbjct: 302 IMK 304 >UniRef50_Q5U3Q3 Cluster: Cytochrome P450, family 3, subfamily c, polypeptide 1 like, 2; n=4; Danio rerio|Rep: Cytochrome P450, family 3, subfamily c, polypeptide 1 like, 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 494 Score = 139 bits (336), Expect = 2e-31 Identities = 71/218 (32%), Positives = 123/218 (56%), Gaps = 4/218 (1%) Query: 335 SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDS 394 S Q ++D EI Q + G++TT+ SF L + + D +K++EE+D+ F Sbjct: 279 SEQPVKGLTDHEILSQSFIFILGGYETTSTTLSFLLHNLATNPDCLEKLVEEIDKNF-PL 337 Query: 395 DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATY 454 D P+++ ++M YLE + E++RL P P + R + + L NG IP T + I TY Sbjct: 338 DTPISYDALMKMDYLEMSINESMRLLPTAPRLERVCKKTVEL--NGITIPKDTLVAIPTY 395 Query: 455 KLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTI 514 L+R P ++ +P +F P+ F PE + YAF+PF GPR+C+G ++A++ +K+++ + Sbjct: 396 VLNRDPQLWDSPQEFRPERFSPENKSEFLQYAFMPFGLGPRNCIGMRFALMIVKLLVVKL 455 Query: 515 LRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552 L+NF + KE+ L+ + + ++L PRKR Sbjct: 456 LQNFS-LETCKETQIPLELTPVFQPKVPITLKLTPRKR 492 >UniRef50_Q9BID0 Cluster: Cytochrome P450; n=27; Culicidae|Rep: Cytochrome P450 - Anopheles gambiae (African malaria mosquito) Length = 501 Score = 139 bits (336), Expect = 2e-31 Identities = 58/178 (32%), Positives = 103/178 (57%), Gaps = 1/178 (0%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 I+ E++ Q G +T++ SF L + ++Q++QDK + + + +T++ Sbjct: 291 ITIEDVAAQAFVFFLAGFETSSTAMSFCLYELALNQELQDKARQNITDVMKQHSS-ITYE 349 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 EMKY+E C+ E++R YPP+ + R+V ++ +P K + G I Y LH P+ Sbjct: 350 AVHEMKYIEMCINESMRKYPPITTLTRRVEKDYRVPDTDKVLQEGIMAAIPVYALHHDPE 409 Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519 +PNP +FDPD F E+ A RH + ++PF GPR C+G ++ M++ ++ L +L++FR Sbjct: 410 HFPNPEQFDPDRFTAEQEAKRHPFVYLPFGEGPRICIGLRFGMMQARIGLVYLLKHFR 467 >UniRef50_Q7QH22 Cluster: ENSANGP00000012679; n=5; Cellia|Rep: ENSANGP00000012679 - Anopheles gambiae str. PEST Length = 526 Score = 138 bits (335), Expect = 3e-31 Identities = 63/188 (33%), Positives = 114/188 (60%), Gaps = 1/188 (0%) Query: 333 LESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG 392 L ++ +G A+S +E+ Q G++T+++ +F L + +++ Q++ + + Sbjct: 304 LRAASNGSALSMDELMAQAFGFFLAGYETSSSNVTFCLYELALNEHCQERARACVREALR 363 Query: 393 DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIA 452 +T++ EM+YL+RC+ ETLR YPP+P++ R ++ +P + +PA + + Sbjct: 364 KHGG-LTYEALGEMEYLDRCINETLRKYPPLPLLPRLTSKAYRIPGSDVILPAKMRIHLP 422 Query: 453 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 512 Y + R YP+P++FDPD F PER A RH+ AF+PF GPR C+G++ +L+ ++ L+ Sbjct: 423 VYAIQRDERYYPDPDRFDPDRFAPERVAERHFSAFLPFGEGPRICIGQRLGVLQSRIGLA 482 Query: 513 TILRNFRV 520 T+L NFRV Sbjct: 483 TVLANFRV 490 >UniRef50_P05184 Cluster: Cytochrome P450 3A3; n=159; Euteleostomi|Rep: Cytochrome P450 3A3 - Homo sapiens (Human) Length = 504 Score = 138 bits (335), Expect = 3e-31 Identities = 73/220 (33%), Positives = 125/220 (56%), Gaps = 10/220 (4%) Query: 322 QKKRLAFLDLLLES------SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGI 375 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + Sbjct: 265 QKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELAT 324 Query: 376 HQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEIT 435 H D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ Sbjct: 325 HPDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVE 383 Query: 436 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495 + NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR Sbjct: 384 I--NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 441 Query: 496 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 535 +C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 NCIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 480 Score = 34.7 bits (76), Expect = 6.5 Identities = 24/128 (18%), Positives = 57/128 (44%), Gaps = 7/128 (5%) Query: 85 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQ 140 H+ K+W G + ++ + DP ++++L Y F ++ + + I+ + Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124 Query: 141 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 197 +W+ R L++PTF LK + + +V L++E D +++++ Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184 Query: 198 LETAMGVS 205 ++ GV+ Sbjct: 185 TSSSFGVN 192 >UniRef50_Q8WQN1 Cluster: Cytochrome P450 CYP4H24; n=23; Culicidae|Rep: Cytochrome P450 CYP4H24 - Anopheles gambiae (African malaria mosquito) Length = 193 Score = 138 bits (334), Expect = 4e-31 Identities = 65/191 (34%), Positives = 110/191 (57%), Gaps = 4/191 (2%) Query: 362 TAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR--PVTFQDTLEMKYLERCLMETLRL 419 T +G SF + H +IQ+K+ E+ + G R P+T+ YL+ + E+LRL Sbjct: 4 TTSGISFTFYQLAKHPEIQEKLYREIQDVLGGEYRHVPLTYNTLQNFPYLDMVVKESLRL 63 Query: 420 YPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERS 479 PPV I R++ +I + NG IPAGT I Y +HR P VYP+P +FDP+ F + Sbjct: 64 LPPVSFIGRRLADDIEM--NGVTIPAGTDFTIPIYVIHRNPVVYPDPERFDPERFSDGNT 121 Query: 480 ANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKR 539 R Y ++PFS G R+C+G++YA+L++KV + ++ +R++ + +L+ D++L+ Sbjct: 122 QRRGPYDYIPFSIGSRNCIGQRYALLEMKVAIVRMVSFYRILPGDTMHEIRLKTDLVLRP 181 Query: 540 AEGFQVRLQPR 550 + ++L R Sbjct: 182 DKSIPIKLVAR 192 >UniRef50_Q0IG08 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 526 Score = 138 bits (334), Expect = 4e-31 Identities = 108/407 (26%), Positives = 188/407 (46%), Gaps = 45/407 (11%) Query: 130 LGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS--NFDCHD 187 LGNGL+ GQKWR R +++P F N ++ + L + + +++E +D + Sbjct: 116 LGNGLISLEGQKWRDMRAMLSPMFTGNKIRHMVPLVGKCAEDLCRFVERETDEVEWDVRE 175 Query: 188 YMSECTVEILLETAMGVSKSTQDQSGFEY---AMAVMKMCDILHL-RHTKIWLRPDLLFK 243 +++C VE++ A G+ + + E+ A +M D+ + R I + P + + Sbjct: 176 LLAKCLVEVIGSCAFGIEVDSFNDPDNEFDRVAKYLMNQSDVRKVARFLLIMVFPKMCKQ 235 Query: 244 FTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLS 303 F K + L + + +++ + S L A + K VEG S Sbjct: 236 F-GMELFDDKYKRLFRRLVSETMLKRESDGVSRPDLIQLLMLARRGKLEADK--DVEGES 292 Query: 304 FGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAIS--DEEIKEQVDTIMFEGHDT 361 F ++ LE+ V S D+E+ Q G DT Sbjct: 293 FAAAND----------------------YLETGTDDVKRSWSDDELTAQAVIFFAAGFDT 330 Query: 362 TAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYP 421 T+ SF L + IH +IQD++ EE+ + SD ++++ ++YL+ + E+LR +P Sbjct: 331 TSTLLSFTLMELAIHPEIQDRLFEEIKSV-QRSDSVISYEQIQSLEYLDAVISESLRKWP 389 Query: 422 PVPIIARQVNQEITL--PSNGK---KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 476 P+ R+ ++ + P +G I G ++ + Y H P +PNP KFDPD F Sbjct: 390 PLTATDRKCTKDYLMVDPEDGSPMFSIEEGYSVWVPIYCFHHDPKYFPNPEKFDPDRF-- 447 Query: 477 ERSANRHYY---AFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520 NRH A++PF GPR+C+G ++A++ K+IL +LR+FRV Sbjct: 448 -NRVNRHQLNPAAYMPFGVGPRNCIGSRFALMSAKMILLRLLRSFRV 493 >UniRef50_O76107 Cluster: Cytochrome P450; n=2; Culicini|Rep: Cytochrome P450 - Culex quinquefasciatus (Southern house mosquito) Length = 499 Score = 138 bits (334), Expect = 4e-31 Identities = 63/198 (31%), Positives = 115/198 (58%), Gaps = 4/198 (2%) Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 Q R F+DLL++ + + EI Q G++T++ +F L + ++Q++Q+ Sbjct: 259 QASRKDFMDLLIKLEDN---FTFNEIAAQAFVFFQAGYETSSITMTFCLYELALNQELQE 315 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 + + ++ + +++ +M++L C+ ETLR YPPV + R++ + +P Sbjct: 316 RARKSVEDVL-KRHGSFSYETIQDMEFLNCCVKETLRKYPPVANLFREITKNYKVPETDI 374 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 + G +VI Y +H PD+YPNP F+P+ F+PE S NRH A++PF GPR+C+G + Sbjct: 375 TLEKGYRVVIPVYGIHHDPDIYPNPEVFNPERFIPELSTNRHPMAYLPFGEGPRTCIGER 434 Query: 502 YAMLKLKVILSTILRNFR 519 +A+++ K+ LS +L+ FR Sbjct: 435 FALMETKIGLSRLLQKFR 452 >UniRef50_UPI00015B5073 Cluster: PREDICTED: similar to cytochrome P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 1350 Score = 137 bits (332), Expect = 6e-31 Identities = 67/196 (34%), Positives = 110/196 (56%), Gaps = 3/196 (1%) Query: 358 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 417 G +TTA+ ++ L + +QDIQ+++ E+ Q+ S +T++ M YL+ ETL Sbjct: 255 GQETTASAITYCLYELSFNQDIQEELYNEISQV-AHSPEGLTYEKLFSMPYLDMVFRETL 313 Query: 418 RLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPE 477 R +P P++ RQ +++ +P + I GT +VI LH PD+YP+P+KFDP F E Sbjct: 314 RKHPGAPMLNRQASEDFVVPGSHFVIKKGTRIVIPIKALHADPDIYPDPDKFDPTRFTSE 373 Query: 478 RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV-ISDLKESDFKLQADII 536 A RH + ++PF GPR C+G++ +LK K+ L +L N++ + D + D Sbjct: 374 NKAKRHAFTYIPFGEGPRHCIGKRLGILKPKIALFYLLLNYKFSVCDKTPIPLRYMTDYF 433 Query: 537 LKRAEGFQVRLQPRKR 552 ++ G QV L+ KR Sbjct: 434 VQVPAG-QVYLKVEKR 448 Score = 35.9 bits (79), Expect = 2.8 Identities = 35/179 (19%), Positives = 75/179 (41%), Gaps = 6/179 (3%) Query: 99 VFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLN 156 +FL DP +++IL H + ++ Y K L GL+ +KW+ R ++PTF Sbjct: 20 LFLMDPELIQLILVKHFNSFYNRGTLYNESKDPLSTGLVRLYDEKWKRLRVKLSPTFTSG 79 Query: 157 VLKSFIDLFNA---NSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVSKSTQDQSG 213 LK L V + + ++ + D + T++ + A G + + Q Sbjct: 80 KLKLMYPLVKEICDELLRVYEDVLDKSDVVEIKDITNRFTIDCISSIAFGFNCDSLHQPD 139 Query: 214 FEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272 E+ D+ + + P L+ F + + K+ + + L +K++ ++++ Sbjct: 140 NEFLKYGKISNDLGRVFLIFSFFVPRLVSLF-PIPEKRKKVSEFFYDLFEKMVSHRRKD 197 >UniRef50_UPI0000D56468 Cluster: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) - Tribolium castaneum Length = 421 Score = 137 bits (332), Expect = 6e-31 Identities = 62/156 (39%), Positives = 100/156 (64%), Gaps = 2/156 (1%) Query: 344 DEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDT 403 D +++++ I+ G +++A + L ++GI+ ++Q K+ ELD IFGD +R TF+ Sbjct: 266 DSPVEDEIQNILITGSESSALALALVLVVLGIYPEVQQKIALELDSIFGDDEREPTFEHI 325 Query: 404 LEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 463 +M+YLE + ETLR+ P VPII R Q+I L IPAG+T+++ + ++ + + Sbjct: 326 NQMEYLECVIKETLRILPIVPIIMRLAEQDIKL--EHCTIPAGSTVLVPIVHISKKSEFW 383 Query: 464 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 PNKF+PD FLP+ ++ RH F+PFS GPR+CVG Sbjct: 384 KEPNKFNPDRFLPKNNSERHRCTFLPFSYGPRNCVG 419 Score = 92.7 bits (220), Expect = 2e-17 Identities = 69/261 (26%), Positives = 119/261 (45%), Gaps = 19/261 (7%) Query: 20 LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79 L +VL + V+ + + SRR LY K++ +A F+GG ++ + Q Sbjct: 10 LIWVLFI-IVLYFLLKYNWSRRWLYYYGSKIDGPFAWPIIGSAHHFIGGQKVFYKKMTQI 68 Query: 80 SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139 Y ++ K W+G L+V P DVE++L+S +K + Y++ GLLI+ Sbjct: 69 FETYP--TLSKFWLGKDLIVITSRPEDVEIVLNS--CFEKPKFYKYAYKLFRTGLLIAPV 124 Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS-NFDCHDYMSECTVEILL 198 W+ R++I PTF+ L++F ++F + +V L++E FD + CT L Sbjct: 125 NIWKERRRMIGPTFNSKTLQTFTEIFGKQANRLVRVLEQECGREFDIFLKLFRCT----L 180 Query: 199 ETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDII 258 +TA G QD Y +++ DI +R WL+ D +K + + K Sbjct: 181 DTACG-----QD----NYLQKLIRAEDIATIRSFSPWLQVDFFWKKSPLGREMDKACAES 231 Query: 259 HGLTKKVIKRKKEEFASGKKP 279 K+++ KK +F P Sbjct: 232 FTFIKQILSLKKCDFKDTTNP 252 >UniRef50_UPI0000D555E9 Cluster: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1) - Tribolium castaneum Length = 514 Score = 137 bits (332), Expect = 6e-31 Identities = 68/213 (31%), Positives = 118/213 (55%), Gaps = 2/213 (0%) Query: 339 GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPV 398 G +++ +E Q G +TT+ SF L M ++ I+ K E++++ G + Sbjct: 300 GTSLTLDEAAAQAFIFFLAGFETTSTTISFALFEMARNESIRTKARTEINKVLGKHGGKL 359 Query: 399 TFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR 458 T++ T+EM+YL+ + ETLR YPP P+ R+ + +P I G +++I Y LHR Sbjct: 360 TYEATMEMEYLDTVISETLRKYPPAPVFLRKCTKTYRVPDTDVIIEEGLSVLIPAYGLHR 419 Query: 459 RPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518 P+ +P+P FDPD F + + Y ++PF GPR C+G ++AM+++K+ L+ IL++F Sbjct: 420 DPEYFPDPETFDPDRFNEDNRSKIWDYTYIPFGDGPRICIGMRFAMIQIKIALALILKSF 479 Query: 519 RV-ISDLKESDFKLQ-ADIILKRAEGFQVRLQP 549 +S+ K++ + IIL G + L P Sbjct: 480 EFPLSEKTILPMKMENSGIILAPIGGIWLNLIP 512 >UniRef50_A5P357 Cluster: Cytochrome P450; n=1; Methylobacterium sp. 4-46|Rep: Cytochrome P450 - Methylobacterium sp. 4-46 Length = 463 Score = 137 bits (332), Expect = 6e-31 Identities = 72/233 (30%), Positives = 130/233 (55%), Gaps = 9/233 (3%) Query: 321 GQKKRLAFLDLLLESS--QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378 G + R L LL+ + +SG A+ D ++ + + T + GH+TTA ++ L ++ +H Sbjct: 235 GVEGRDDLLSLLVAARDPESGRAMDDRDVADNLLTFVTAGHETTALALAWTLYLLALHPA 294 Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438 I+ +V+ E++ + G P+ + + + + E +RLYPP P++ R +E+ + Sbjct: 295 IEARVVAEVEAVTGGG--PLAPHHVEALGFTRQAIQEAMRLYPPAPVLVRAALEEVDV-- 350 Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 G +I GT + + Y +HR ++ P++FDPD F PE + R YA++PF AGPR C+ Sbjct: 351 GGHRIGPGTPVTVPIYAIHRHALLWDEPDRFDPDRFAPEAAKARDRYAYLPFGAGPRICI 410 Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDF-KLQADIILKRAEGFQVRLQPR 550 G +A+++ IL+ ++R+ R L+ L+ I L+ AEG +R+ PR Sbjct: 411 GMSFALMEAVAILAVLIRDLRFA--LRPGFVPTLKQRITLRPAEGMPMRVAPR 461 Score = 39.1 bits (87), Expect = 0.30 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 4/111 (3%) Query: 96 RLLVFLYDPRDVEVILSSHVY-IDKAEEYR-FFKPWLGNGLLISTGQKWRSHRKLIAPTF 153 R +F+ DP V +L +K+E R P LG+ +L + G +WR R+ AP F Sbjct: 58 RATLFVMDPGLVRTVLVDRAESFEKSEVLRRSLSPALGDAILTADGARWRWQRRAAAPIF 117 Query: 154 HLNVLKSFIDLFNANSRAVVDKLK--KEASNFDCHDYMSECTVEILLETAM 202 + F+ A + + LK + D M T +I+ T + Sbjct: 118 RNERILGFLPAMIAAAERTREALKGLPPGTEADLAQVMMRTTFDIIAATML 168 >UniRef50_Q3E385 Cluster: Cytochrome P450; n=3; Chloroflexus|Rep: Cytochrome P450 - Chloroflexus aurantiacus J-10-fl Length = 452 Score = 137 bits (331), Expect = 8e-31 Identities = 73/232 (31%), Positives = 123/232 (53%), Gaps = 4/232 (1%) Query: 289 SEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIK 348 S P+ G L L + + + G+ L + + + +G +S ++I+ Sbjct: 193 SWPTPGNLQYRRNLELLERTVYRLIEERRQHQGEHDDLLEMLVTARDADTGEQMSPKQIR 252 Query: 349 EQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKY 408 ++V TI GH+TTA S+ L ++ H + + K+ E + G R T D ++ Y Sbjct: 253 DEVMTIFLAGHETTAGTLSWILHLLAHHGESERKLRAEYATVLGG--RNPTPADLPQLPY 310 Query: 409 LERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNK 468 + ETLRLYPP I++R + + TL ++PAG + ++ Y HR PD +PN Sbjct: 311 NRMVIDETLRLYPPTWILSRVLVEADTL--GDYELPAGAVVALSPYVTHRHPDFWPNAES 368 Query: 469 FDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520 FDP+ F P RH +A++PF GPR C+G +A++++++IL IL++FRV Sbjct: 369 FDPERFRPTAIEQRHKFAYIPFITGPRQCIGNNFALMEMQLILPMILQHFRV 420 >UniRef50_Q9V4T3 Cluster: Probable cytochrome P450 4ad1; n=2; Sophophora|Rep: Probable cytochrome P450 4ad1 - Drosophila melanogaster (Fruit fly) Length = 516 Score = 137 bits (331), Expect = 8e-31 Identities = 77/203 (37%), Positives = 110/203 (54%), Gaps = 4/203 (1%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 GQ FLD+LL + G + + EI E+V T +F GHD AA SF L + H +IQ Sbjct: 269 GQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQ 328 Query: 381 DKVIEELDQIFGDSDRPVTFQDTL-EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 K EE +IFG++ L +M YLE + ETLRLYP VP+IAR I + N Sbjct: 329 QKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDI--N 386 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNF-LPERSANRHYYAFVPFSAGPRSCV 498 G K+ TT+++ + + +P F P+ F P + + VPFSAGPR C+ Sbjct: 387 GTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRCI 446 Query: 499 GRKYAMLKLKVILSTILRNFRVI 521 K+AM ++K +LS +LR F ++ Sbjct: 447 AEKFAMYQMKALLSQLLRRFEIL 469 Score = 110 bits (264), Expect = 1e-22 Identities = 59/218 (27%), Positives = 111/218 (50%), Gaps = 4/218 (1%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120 N +F A+ + ++Q YD + + + + + L DP +++ ILSS + K Sbjct: 46 NLFQFGLKPAEYPKKVLQYCRKYDFQGFRSL-VFLQYHMMLSDPAEIQNILSSSSLLYKE 104 Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180 Y F +PWLG+GLL S+G +W H+KL AP F + ++ ++ + + V KL + Sbjct: 105 HLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLS 164 Query: 181 SN---FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLR 237 FD + +++CT++I+ E A G S+ + + A+ +CD++ R I R Sbjct: 165 DTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKR 224 Query: 238 PDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFAS 275 D LF+ T Y Q + L ++ ++I +++ + A+ Sbjct: 225 FDALFRLTSYYMKQRRALSLLRSELNRIISQRRHQLAA 262 >UniRef50_Q3I414 Cluster: Cytochrome P450; n=18; Cucujiformia|Rep: Cytochrome P450 - Leptinotarsa decemlineata (Colorado potato beetle) Length = 510 Score = 136 bits (330), Expect = 1e-30 Identities = 65/210 (30%), Positives = 114/210 (54%), Gaps = 1/210 (0%) Query: 334 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 393 E + G +++ +EI Q G +T++ +F L + H +IQ+KV E++ + Sbjct: 290 EHTGDGTSLTMDEIVAQSFVFFIAGFETSSTTMTFALYQLATHPEIQEKVRSEINSVLEK 349 Query: 394 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIAT 453 + +T+ E+KY+ + + ETLR+YP +P++ R+ ++ +P + I G + I Sbjct: 350 HNNQITYDALNELKYMGKVIDETLRMYPALPVVTRRCVEDYRIPDSDVIIEKGIEVFIPI 409 Query: 454 YKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILST 513 +H P+ Y NP FDP+ F E RH YA +PF GPR C+G ++ +++ KV L + Sbjct: 410 KAIHYDPEYYENPEVFDPERFNEENIQGRHPYAHIPFGEGPRICIGLRFGVMQSKVGLVS 469 Query: 514 ILRNFRV-ISDLKESDFKLQADIILKRAEG 542 IL+NFRV +S + K+ + + EG Sbjct: 470 ILKNFRVTLSSKTKLPLKIDVNSFIPTTEG 499 >UniRef50_UPI0000D576F7 Cluster: PREDICTED: similar to Cytochrome P450 6a8 (CYPVIA8); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a8 (CYPVIA8) - Tribolium castaneum Length = 491 Score = 136 bits (328), Expect = 2e-30 Identities = 66/174 (37%), Positives = 100/174 (57%) Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404 EE+ Q G +T+ A SF L + HQDIQ KV EE + + +T++ Sbjct: 284 EEVASQCVLFFIAGFETSHATMSFALYELAKHQDIQQKVREEFWAVVDSQESEITYEAVQ 343 Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464 ++KYL++ L ETLR YP V + R+ ++ +P +G I GTT++I T L+ + YP Sbjct: 344 KLKYLDQVLNETLRKYPVVMYLTRRCIKDYKVPEDGAVIEKGTTVIIPTVALNYDENYYP 403 Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518 NP KFDP F E RH +PF GPR C+GR++A++++KV L +L+N+ Sbjct: 404 NPKKFDPQRFSEENKKLRHPCIHLPFGLGPRFCIGRRFALIQVKVGLVLLLKNY 457 >UniRef50_Q0LLJ2 Cluster: Cytochrome P450; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 459 Score = 136 bits (328), Expect = 2e-30 Identities = 66/221 (29%), Positives = 125/221 (56%), Gaps = 4/221 (1%) Query: 331 LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390 LL +G ++D++++++V T+ GH+TTA ++ ++ +++ ++ E+D++ Sbjct: 232 LLSIDDGNGQGMTDQQVRDEVVTLFLAGHETTANTLTWCSYLLSQAPEVRQRLQAEVDEV 291 Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450 RPVT QD ++ Y E + ETLR+YPP ++ +V E + G+ I + Sbjct: 292 L--QGRPVTLQDLQKLPYTEMVIKETLRMYPPAYALSARVPTE-NITVLGQTITPRQAAM 348 Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVI 510 ++ Y +H P +P P +FDP+ F PE+ RH YA++PF AG R C+G +AM++ +++ Sbjct: 349 VSPYAMHHNPRYWPEPERFDPERFSPEQERARHKYAYIPFGAGSRVCIGNVFAMMEAQLL 408 Query: 511 LSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 L+T+++++ D + + I L G +VRL R+ Sbjct: 409 LATMMQHYDFTLDPTQR-VEYDPQITLGVKHGLRVRLAQRQ 448 Score = 48.8 bits (111), Expect = 4e-04 Identities = 30/128 (23%), Positives = 64/128 (50%), Gaps = 3/128 (2%) Query: 93 IGPRLLVFLYDPRDV-EVILSSHVYIDK-AEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 150 +GP + + DP + E+++++ + K + +LGNGLL + G + RKL+ Sbjct: 44 MGPFRVYLVNDPAGIQELLVTNRDKVRKNGGDRELLSRFLGNGLLSNDGADHQKQRKLVQ 103 Query: 151 PTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVSKSTQD 210 P FH+ ++++ + +++A++++ + + D M E T+ I+ +T S Q+ Sbjct: 104 PAFHMKRIQAYAETMVEHTQAMLERW-HDGAILDMDQAMMELTLTIVTKTLFNADISEQE 162 Query: 211 QSGFEYAM 218 AM Sbjct: 163 VRQVSQAM 170 >UniRef50_UPI00015B5352 Cluster: PREDICTED: similar to cytochrome P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 507 Score = 135 bits (327), Expect = 3e-30 Identities = 71/239 (29%), Positives = 130/239 (54%), Gaps = 11/239 (4%) Query: 325 RLAFLDLLLESSQS--GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 R + LL+++ + G+ ++ ++I Q G ++T++ F L + + DIQD+ Sbjct: 269 RQDMMQLLIQAMKKDDGIKVTMDDIIGQAFFFFLAGFESTSSAMCFALQELAANPDIQDR 328 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 + +E+D +T++ + +KYL+ + ETLR YPPV I R N+E T P + Sbjct: 329 LRQEIDDEIEQHGGELTYESLVNLKYLDMVMSETLRKYPPVAITNRLCNKEYTFPPLMEG 388 Query: 443 IP-----AGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 497 P GT+++I+ + LHR P +P+P KFDP+ F E + Y ++PF GPR C Sbjct: 389 YPEYQMEVGTSILISMFGLHRDPKYFPDPEKFDPERFNDENKHKINPYTYMPFGIGPRQC 448 Query: 498 VGRKYAMLKLKVILSTILRNFRVISDLKESDFKL---QADIILKRAEGFQVRLQPRKRM 553 + ++A+++ K+++ ILR F V+ ++S + + IL EG+ + + RK++ Sbjct: 449 IANRFALMEAKIVIIDILRKF-VVKFTEKSHHPVTLSKKTFILSAEEGYWFKFEGRKKV 506 Score = 36.3 bits (80), Expect = 2.1 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 7/132 (5%) Query: 128 PWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKL---KKEASNFD 184 P +G + GQ+W+ R + P++ +K L S+ V + A NF+ Sbjct: 116 PIVGRNIFSLRGQRWKEVRNTLTPSYTAARIKMLFALVAECSKDFVQYFVDHPELAENFE 175 Query: 185 CHDYMSECTVEILLETAMGV---SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLL 241 D ++ T +++ A GV S QD + + V + L+ T + P+++ Sbjct: 176 AKDAITRYTNDVVASAAFGVKVDSMKDQDNEFYLHGKEVTNFSALAALKFTILKNFPNIM 235 Query: 242 -FKFTDYAKNQT 252 F T + N T Sbjct: 236 KFFGTTFLPNAT 247 >UniRef50_Q98T91 Cluster: Cytochrome P450 3A40; n=16; Euteleostomi|Rep: Cytochrome P450 3A40 - Oryzias latipes (Medaka fish) (Japanese ricefish) Length = 502 Score = 135 bits (327), Expect = 3e-30 Identities = 75/237 (31%), Positives = 133/237 (56%), Gaps = 12/237 (5%) Query: 322 QKKRLAFLDLLLES---SQSGV---AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGI 375 QK R+ FL L+++S +Q+G+ +SD EI Q +F G++TT++ +F + Sbjct: 265 QKSRIDFLQLMIDSQKNNQNGLQDKGLSDHEILSQAMIFIFAGYETTSSSLTFLAYNLAT 324 Query: 376 HQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEIT 435 + ++ K+ +E+D F + PV + +EM+YL+ + E+LRLYP + R + T Sbjct: 325 NPEVMKKLQKEIDATFPNK-APVQYVPLMEMEYLDCVVNESLRLYPIAARLERVA--KAT 381 Query: 436 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495 + NG IP +++ T+ LHR P+++P P KF P+ F E Y ++PF AGPR Sbjct: 382 VEVNGLVIPKDMVVMVPTWPLHRDPELWPEPEKFKPERFSKENKDTFDPYTYMPFGAGPR 441 Query: 496 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI--ILKRAEGFQVRLQPR 550 +C+G ++A++ +K+ + IL+ + S KE++ + D+ L Q++L PR Sbjct: 442 NCIGMRFALVMMKLAVVEILQTYD-FSVCKETEVPFEMDVQGFLAPKRPIQLKLTPR 497 Score = 41.9 bits (94), Expect = 0.043 Identities = 26/138 (18%), Positives = 61/138 (44%), Gaps = 6/138 (4%) Query: 91 IWIGPRLLVFLYDPRDVEVILSSHVY--IDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148 I+ G + ++ + DP ++ +L Y +R P L + + I+ +W+ R + Sbjct: 74 IYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFRLNGP-LYDAVSIAEDDQWKRIRSV 132 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 205 ++P+F LK D+ +S ++ +KK+ + +Y +++++ TA V Sbjct: 133 LSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEMKEYFGPYSMDVVTSTAFSVD 192 Query: 206 KSTQDQSGFEYAMAVMKM 223 + + + + KM Sbjct: 193 IDSLNNPSDPFVTNIKKM 210 >UniRef50_Q9PWP0 Cluster: Cytochrome P450; n=2; Dicentrarchus labrax|Rep: Cytochrome P450 - Dicentrarchus labrax (European sea bass) Length = 526 Score = 135 bits (326), Expect = 3e-30 Identities = 63/184 (34%), Positives = 110/184 (59%), Gaps = 3/184 (1%) Query: 323 KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 +K+ F+D++L S + G ++DEEI+ + +T MF GHDTTA+ + L + H Q+ Sbjct: 292 QKKKDFVDIILLSRDEDGQGLTDEEIQAEANTFMFAGHDTTASAICWTLYNLARHDQYQE 351 Query: 382 KVIEELDQIFGDSDR-PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 K +E+ ++ DR + ++D + + C+ E+LRL+ PV + R+ Q++TLP + Sbjct: 352 KCRQEVMELMEGRDRHEIEWEDLSNLPFTTMCIRESLRLHSPVQAVTRKYTQDMTLPGDC 411 Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +P G +++ Y H P V+ NP++F P F P +AF+PFS+GPR+C+G+ Sbjct: 412 T-VPKGAICLVSIYGTHHNPTVWTNPHEFHPLRFDPTNKEGLAAHAFIPFSSGPRNCIGQ 470 Query: 501 KYAM 504 K+A+ Sbjct: 471 KFAL 474 Score = 101 bits (242), Expect = 5e-20 Identities = 56/186 (30%), Positives = 105/186 (56%), Gaps = 8/186 (4%) Query: 92 WIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 148 ++GP LV L+ P V+ +L + I +E Y +PWLG LL+S G++W R+L Sbjct: 93 FLGPFYHLVRLFHPDYVKPLLMAPASITVKDELIYGHLRPWLGQSLLLSNGEEWSRKRRL 152 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDK----LKKEASNFDCHDYMSECTVEILLETAMGV 204 + P FH ++L++++ +FN ++ + DK L +N + D+++ T++ LL+ A Sbjct: 153 LTPAFHFDILRNYVAIFNTSTNTMHDKWRHHLAVGTTNLEMFDHITLMTLDSLLKCAFSY 212 Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264 + + Q QS EY A++++ D++ R KI D ++ T K K L I+H T++ Sbjct: 213 NSNCQ-QSTSEYVSAIVELSDLIIDRRQKILHHWDWIYWKTKQGKRFKKALSIVHRFTRE 271 Query: 265 VIKRKK 270 V+++++ Sbjct: 272 VVQKRR 277 >UniRef50_Q8WQN9 Cluster: Cytochrome P450 CYP4J5; n=22; Endopterygota|Rep: Cytochrome P450 CYP4J5 - Anopheles gambiae (African malaria mosquito) Length = 153 Score = 134 bits (325), Expect = 4e-30 Identities = 66/154 (42%), Positives = 96/154 (62%), Gaps = 4/154 (2%) Query: 350 QVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRP---VTFQDTLEM 406 +VDT MFEGHDTT + F L + +IQ ++ +EL Q+ +D ++ D Sbjct: 1 EVDTFMFEGHDTTGSALVFILLTLSWELEIQTRLHQELSQLATQNDLTDGHLSPNDLNSA 60 Query: 407 KYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNP 466 K+ +R + E LRL+PPV I+R V +EI LP +G+ IP G + + LHR P +P+P Sbjct: 61 KFFDRVIKECLRLWPPVAFISRSVTEEIHLP-DGRIIPQGCIANLHIFDLHRDPAQFPDP 119 Query: 467 NKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500 +FDPD FLPE + R YA++PFSAGPR+C+G+ Sbjct: 120 ERFDPDRFLPECVSQRSPYAYIPFSAGPRNCIGQ 153 >UniRef50_UPI0000E4963D Cluster: PREDICTED: similar to cytochrome P450 3A69; n=7; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cytochrome P450 3A69 - Strongylocentrotus purpuratus Length = 508 Score = 134 bits (324), Expect = 6e-30 Identities = 95/386 (24%), Positives = 168/386 (43%), Gaps = 17/386 (4%) Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEI 196 Q W+ R +I PTF +K L N +S +V ++++ N T++ Sbjct: 75 QHWKDVRNVITPTFSAVKMKQLSGLLNESSDTLVKNFGAIQEKEGNVKVFSLFEAFTMDG 134 Query: 197 LLETAMGVSKSTQDQSG---FEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTK 253 + + A G+ +Q+ +A +MK L I+ R + + + + + Sbjct: 135 IAKCAFGIQVDSQNDPSDPFVTHAKDLMKNRFALKFVIAGIFPRIGKIMDYFEVSTLPPE 194 Query: 254 LLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXX 313 + + + I +KE S K L ++ + + +E + K Sbjct: 195 VSSFFISVVDQAIAARKESGGS-KMKDFLQLMLNAAQENKSEKEMIEE----KPQDEKVE 249 Query: 314 XXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMM 373 + ++ DL ++ +EI Q G+DT F + Sbjct: 250 GDLYALIEDQDNKSYFDL---KKSKKTTLTKDEIYGQAMLFFLAGYDTINTTLGFLTYSL 306 Query: 374 GIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQE 433 + ++QDK+IEE+D D V + +M YL+ + E LRLYP II RQ N+ Sbjct: 307 ATNPEVQDKLIEEIDNETPARD-DVGYNSVAKMSYLDNVVCEILRLYPAGLIIERQCNE- 364 Query: 434 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAG 493 T NG IP + + Y +HR P ++P+P KFDP+ F E RH A++PF AG Sbjct: 365 -THVCNGLTIPKDSQIFFPVYAIHRDPAIWPDPEKFDPERFTKENREGRHPLAWMPFGAG 423 Query: 494 PRSCVGRKYAMLKLKVILSTILRNFR 519 PR+C+G ++A++++K+ +L+ +R Sbjct: 424 PRNCIGMRFALMEIKMATVRLLQKYR 449 >UniRef50_UPI0000E48EAF Cluster: PREDICTED: similar to cytochrome P450 CYP3A24; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cytochrome P450 CYP3A24 - Strongylocentrotus purpuratus Length = 412 Score = 134 bits (324), Expect = 6e-30 Identities = 59/189 (31%), Positives = 108/189 (57%), Gaps = 3/189 (1%) Query: 332 LLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIF 391 L + S S + +++ E+ Q G++TT + L ++ H D+QDK++ E+D + Sbjct: 195 LQKKSSSKIRLNESEVISQALIFFLAGYETTNTTCGYMLYLLATHPDVQDKLVNEIDDVA 254 Query: 392 GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVI 451 +++ V +Q +M YLE+ ET R+YPP + R N+ + NG +P G + I Sbjct: 255 PEAE-DVGYQSISKMPYLEQIFCETERIYPPALMTDRVCNEPFDI--NGFTVPKGMRIFI 311 Query: 452 ATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVIL 511 + +H P+++P+P +DPD F E H A++PF GPR+CVG ++AM++ K+++ Sbjct: 312 PIFTIHHDPNLWPDPETYDPDRFSKENREKHHPCAWMPFGTGPRNCVGMRFAMMEAKMVI 371 Query: 512 STILRNFRV 520 IL+ +++ Sbjct: 372 VRILQKYQI 380 >UniRef50_UPI000065CBAF Cluster: Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS) (Cytochrome P450 5A1).; n=1; Takifugu rubripes|Rep: Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS) (Cytochrome P450 5A1). - Takifugu rubripes Length = 391 Score = 134 bits (323), Expect = 8e-30 Identities = 63/181 (34%), Positives = 110/181 (60%), Gaps = 3/181 (1%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 I+++EI Q + G++T++ +F ++ I+ + Q ++ +E+D F + P + Sbjct: 205 ITEDEIVGQAFVFLVAGYETSSNTLAFACYLLAINPECQRELQKEVDHFFTRHESP-DYT 263 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 + E+KYL+ + ETLRLYPP AR++ ++ + NG+ P G T I LHR P+ Sbjct: 264 NVQELKYLDMVISETLRLYPPGFRFAREIERDCVV--NGQSFPKGATFEIPAGFLHRDPE 321 Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVI 521 +P+P+KF P+ F PE A+RH + ++PF AGPR+CVG + A L++K+ L + R F ++ Sbjct: 322 HWPDPDKFIPERFTPEAKASRHPFVYIPFGAGPRNCVGMRLAQLEMKMALVRLFRRFNLL 381 Query: 522 S 522 + Sbjct: 382 A 382 Score = 40.3 bits (90), Expect = 0.13 Identities = 20/90 (22%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 124 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV---DKLKKEA 180 RF + + LL+ ++W+ R ++ P F + +K + L N + A++ D + A Sbjct: 37 RFITKPMSDCLLMLRNERWKRVRSILTPAFSASKMKEMVPLINTATDALIKNLDAFAESA 96 Query: 181 SNFDCHDYMSECTVEILLETAMGVSKSTQD 210 F+ H T++++ A G +Q+ Sbjct: 97 EAFNIHKCFGCFTMDVVASVAFGTQVDSQN 126 >UniRef50_Q1D9Z9 Cluster: Cytochrome P450 family protein; n=1; Myxococcus xanthus DK 1622|Rep: Cytochrome P450 family protein - Myxococcus xanthus (strain DK 1622) Length = 458 Score = 134 bits (323), Expect = 8e-30 Identities = 65/194 (33%), Positives = 117/194 (60%), Gaps = 6/194 (3%) Query: 329 LDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 L +++E+ +G +SD +++++V T++ GH+TTA+ ++ + ++ H ++ + E Sbjct: 240 LQMMMEAHDDDTGERMSDSQLRDEVLTLLLAGHETTASALAWTIMLLSQHPGVRRDMESE 299 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 L + G R T +D ++ R + E+LRLYPP ++R +E + G +IP G Sbjct: 300 LARELG--GRNPTHEDLPRLELTHRVVDESLRLYPPAWALSRIATKEDLV--GGFRIPKG 355 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 L+IA + HR P ++ NP FDPD FLPER R +A+ PF GPR C+G ++A+++ Sbjct: 356 AHLLIAPWVTHRHPSIWDNPEGFDPDRFLPEREQARPRFAWFPFGGGPRQCIGNQFALME 415 Query: 507 LKVILSTILRNFRV 520 L ++L+T+L+ R+ Sbjct: 416 LVLVLATLLQRVRL 429 Score = 52.4 bits (120), Expect = 3e-05 Identities = 37/134 (27%), Positives = 60/134 (44%), Gaps = 7/134 (5%) Query: 84 DHESVVKIWIGPRLLVFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLGNGLLISTGQK 141 ++ VV++ +GP LV + P V +L H Y ++ +R + LG+GLL S G Sbjct: 44 EYGDVVRLPMGPADLVLVAHPDGVRHVLQDHARNYSKQSRGFRVLQELLGHGLLTSDGDH 103 Query: 142 WRSHRKLIAPTFHLNVLKSFIDLF---NANSRAVVDKLKKEASNFDCHDYMSECTVEILL 198 W R+L P FH + F A+ A ++ + F+ + + T+ I Sbjct: 104 WLRQRRLAQPAFHRQRVAGFTRTMVDAAADLAATMEARADTGAAFNVAEDFTRLTLRIAS 163 Query: 199 ETAMG--VSKSTQD 210 T G VS +T D Sbjct: 164 STLFGADVSSATHD 177 >UniRef50_Q5TXA2 Cluster: ENSANGP00000026709; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000026709 - Anopheles gambiae str. PEST Length = 198 Score = 134 bits (323), Expect = 8e-30 Identities = 64/198 (32%), Positives = 118/198 (59%), Gaps = 5/198 (2%) Query: 326 LAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIE 385 + FLD LL + + G + +EI+ + TI+ G +TTA +F L M+ +H ++QD+V E Sbjct: 1 MVFLDQLLHTQRGGRDLEMQEIENHLYTIIGAGSETTANQVAFILLMIAMHPEVQDRVHE 60 Query: 386 ELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445 E+ I+G + +++ YLE+ + ET+R+YP P+I R+ + + L +P+ Sbjct: 61 EIVSIYGRAAPDFSYETISAQTYLEQVIKETMRVYPVAPLIGRETIETVKL--GDVIVPS 118 Query: 446 GTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPE--RSANRHYYAFVPFSAGPRSCVGRKY 502 G TL+I LHR +++ + FDPD F P + +H ++++PF GPR+C+G +Y Sbjct: 119 GVTLLINILTLHRNKELWGERAHVFDPDRFDPALYDAKKQHPFSYIPFGGGPRNCIGYRY 178 Query: 503 AMLKLKVILSTILRNFRV 520 M +K++++ +LR +++ Sbjct: 179 GMFAMKIMVTQVLRKYQL 196 >UniRef50_Q495Y1 Cluster: CYP3A43 protein; n=4; Homo sapiens|Rep: CYP3A43 protein - Homo sapiens (Human) Length = 393 Score = 134 bits (323), Expect = 8e-30 Identities = 71/218 (32%), Positives = 120/218 (55%), Gaps = 9/218 (4%) Query: 322 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 376 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 155 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 214 Query: 377 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 436 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 215 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 273 Query: 437 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496 NG IP G +++ Y LH P + P KF P+ F + + Y ++PF AGPR+ Sbjct: 274 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 331 Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 534 C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 332 CIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 368 >UniRef50_Q0IEL1 Cluster: Cytochrome P450; n=6; Culicini|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 511 Score = 133 bits (322), Expect = 1e-29 Identities = 73/214 (34%), Positives = 118/214 (55%), Gaps = 8/214 (3%) Query: 341 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 400 ++S +E+ QV G++T+++ SF L + HQDIQ KV +E+D + + + +T+ Sbjct: 297 SLSIDEVTAQVMVFFVAGYETSSSTVSFCLFELARHQDIQAKVHQEIDTVLAEHEGNLTY 356 Query: 401 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 460 MKYLE+CL ET+R YPPV I+ R+ + +P + GT +V+ +HR P Sbjct: 357 ASLASMKYLEQCLEETVRKYPPVAILNRECTKTYRIPETDVIVEKGTPIVVPLMGMHRDP 416 Query: 461 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520 +P PN F PD F E A A+ F AGPR C+G + +L+ KV + T+LR F+ Sbjct: 417 QYFPQPNDFQPDRF--EGGAQSK--AYFGFGAGPRLCIGMRLGILQSKVAVVTLLRKFKF 472 Query: 521 -ISDLKESDFKLQ---ADIILKRAEGFQVRLQPR 550 +++ ++ +L+ IL G Q+ +Q R Sbjct: 473 SLANPEDQHTELRMKPRSFILTTEGGIQLVVQQR 506 >UniRef50_A7DM29 Cluster: Cytochrome P450; n=2; Methylobacterium extorquens PA1|Rep: Cytochrome P450 - Methylobacterium extorquens PA1 Length = 471 Score = 133 bits (321), Expect = 1e-29 Identities = 72/224 (32%), Positives = 125/224 (55%), Gaps = 9/224 (4%) Query: 329 LDLLLESS--QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 L LLL++ ++G +SDE + + + T + GH+TTA + L ++ H ++ ++++E Sbjct: 252 LGLLLQAKDPETGERLSDESLIDNLLTFVAAGHETTALALIWTLRVLADHPAVEARILDE 311 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 + + G P + + + ++E +RLYPP P+I R+ +E+ L IPAG Sbjct: 312 IAGL-GADPAPEALD---RLAFTRQVVLEVMRLYPPAPLIVRRTAEEVRL--GDMVIPAG 365 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 ++ + Y LHR ++ P+ FDPD F PE +A+R YA++PF AGPR C+G A+ + Sbjct: 366 ESVHVPVYALHRHQSLWERPDVFDPDRFAPELTASRDRYAYLPFGAGPRVCIGMGLALTE 425 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 VIL+T+L FR + E Q + L+ G ++++ PR Sbjct: 426 CLVILATLLPAFRFVPAKAEMP-ATQFRVTLRPKGGMKMKVVPR 468 Score = 37.5 bits (83), Expect = 0.92 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Query: 70 ADIFRNIVQKSAD--YDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEY--RF 125 A + R++++ D Y V ++G R ++ P + ++ + E + R Sbjct: 32 ATMLRSLIEAWPDEVYTRPLVTTRFLGQRT-TYVCAPGHIRSLIVDQAGALEREPFMLRA 90 Query: 126 FKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFI 162 P LG+G+L + G WR R+ AP F + +K+FI Sbjct: 91 LAPALGSGILTADGPHWRGQRRTAAPMFRPDRVKAFI 127 >UniRef50_Q9PVE8 Cluster: Cytochrome P450 3A30; n=4; Percomorpha|Rep: Cytochrome P450 3A30 - Fundulus heteroclitus (Killifish) (Mummichog) Length = 496 Score = 133 bits (321), Expect = 1e-29 Identities = 72/236 (30%), Positives = 132/236 (55%), Gaps = 11/236 (4%) Query: 322 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 376 QK R+ FL L+++S +Q +++D EI Q +F G++T+++ +F + + Sbjct: 264 QKSRVDFLQLMIDSQKNSGAQQDKSLTDHEILSQSMIFIFAGYETSSSSLTFLAYNLATN 323 Query: 377 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 436 ++ K+ EE+D F + PV +Q +EM+YL+ + E+LRL+P + R + + Sbjct: 324 PEVMKKLQEEIDATFPNK-APVHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAAVEI 382 Query: 437 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496 NG IP ++I T+ LHR P+++P P F P+ F + N Y ++PF +GPR+ Sbjct: 383 --NGVVIPKDMVVMIPTWPLHRDPEIWPEPEAFKPERFSKKNKDNIDPYIYMPFGSGPRN 440 Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI--ILKRAEGFQVRLQPR 550 C+G ++A++ +K+ + IL+ + S KE++ + DI +L Q++L PR Sbjct: 441 CIGMRFALVLIKLAVVEILQQYS-FSVCKETEVPFEMDIQGLLAPKRPIQLKLVPR 495 Score = 39.1 bits (87), Expect = 0.30 Identities = 25/138 (18%), Positives = 62/138 (44%), Gaps = 6/138 (4%) Query: 91 IWIGPRLLVFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148 I+ G + ++ + DP ++ +L + +R P L + + I+ +W+ R + Sbjct: 73 IYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNFRLNGP-LYDAVSIAEDDQWKRIRSV 131 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 205 ++P+F LK ++ +S ++ +KK+A D ++ +++++ TA V Sbjct: 132 LSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKDEPLDLKEFFGSYSMDVVTSTAFSVD 191 Query: 206 KSTQDQSGFEYAMAVMKM 223 + + + + KM Sbjct: 192 IDSLNNPSDPFVTNIKKM 209 >UniRef50_O76345 Cluster: Cytochrome P450; n=1; Homarus americanus|Rep: Cytochrome P450 - Homarus americanus (American lobster) Length = 518 Score = 132 bits (320), Expect = 2e-29 Identities = 59/198 (29%), Positives = 120/198 (60%), Gaps = 9/198 (4%) Query: 329 LDLLLESSQSGV-----AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383 L LL++++ + V ++DEE+ + + G +TT+ ++ ++ ++ DIQ+K+ Sbjct: 266 LQLLVDAADANVDASKTKLTDEEVVDNAFLFLLAGFETTSTALTYTSYLLALNPDIQEKI 325 Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQEITLPSNGKK 442 +E++++ G +R +++D ++ Y E +E+ R+YPPV I RQ Q+ Sbjct: 326 FQEVEEVVG-LERAPSYEDLSKLVYTEAVALESTRMYPPVTGFITRQATQDWQY--GPYT 382 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 IPAGT + + + +H P++YP P F P+ FLP+ +RH A++ F GPR+C+G ++ Sbjct: 383 IPAGTEVEVPVWSIHHNPELYPQPELFKPERFLPKAKKDRHTMAYLGFGGGPRNCLGLRF 442 Query: 503 AMLKLKVILSTILRNFRV 520 A++++K++LS++++ F + Sbjct: 443 ALMEMKLVLSSVIQRFYI 460 >UniRef50_Q70AR5 Cluster: Putative cytochrome P450; n=1; Streptomyces peucetius|Rep: Putative cytochrome P450 - Streptomyces peucetius Length = 477 Score = 132 bits (319), Expect = 2e-29 Identities = 60/184 (32%), Positives = 108/184 (58%), Gaps = 4/184 (2%) Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396 +SG +DE+I+++V GH+T + S+ ++ ++ + + ++ E+D++ + R Sbjct: 265 ESGGMFTDEQIRDEVSGFFVAGHETVSTALSWTWYLLSLNPESRRRLQAEVDEVL--AGR 322 Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456 T D ++ Y L E++RLYPP+ + R ++ + G IP G +V+ Y Sbjct: 323 VPTVDDLPKLTYTTMVLQESMRLYPPIFVYMRCAAEDDVI--GGYHIPEGRWVVVCPYVT 380 Query: 457 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 516 HR P+ + NP F+P+ F PE SANRH A++PF AGPR C+G +AML++ ++++ I + Sbjct: 381 HRHPEFWDNPEGFEPERFTPENSANRHRMAYLPFGAGPRKCIGDSFAMLQMPLVVAMIAQ 440 Query: 517 NFRV 520 FR+ Sbjct: 441 RFRL 444 Score = 46.4 bits (105), Expect = 0.002 Identities = 34/144 (23%), Positives = 64/144 (44%), Gaps = 5/144 (3%) Query: 130 LGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYM 189 +G+GL+ + G W R+L P FH ++L+ F D F A++ ++D ++ A + + D Sbjct: 109 VGDGLVAAEGTSWLRSRRLTQPAFHRDILRRFGDSFTASTAELLDGWERRARDGEPLDIK 168 Query: 190 SECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAK 249 SE L A + ++ AV + H R T P KF A+ Sbjct: 169 SEMMHLSLANLARALFRTEWTDEVSRIEPAVQEALGFTHRRMTS----PVDPLKFPSAAR 224 Query: 250 NQTK-LLDIIHGLTKKVIKRKKEE 272 + + L+ I+ L ++ ++ + Sbjct: 225 TRFRGALETINSLLYPMVAERRRD 248 >UniRef50_Q9VGB5 Cluster: Probable cytochrome P450 313a5; n=2; Drosophila melanogaster|Rep: Probable cytochrome P450 313a5 - Drosophila melanogaster (Fruit fly) Length = 487 Score = 132 bits (319), Expect = 2e-29 Identities = 74/217 (34%), Positives = 120/217 (55%), Gaps = 4/217 (1%) Query: 327 AFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 A +D +L + G +S +++ + I+F DT + + L +M + QD V EE Sbjct: 263 ALIDRILNLVRIG-ELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEE 321 Query: 387 LDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445 L ++F + + D ++ L+R L ET+RL P VP++ RQ + I L SNG IP Sbjct: 322 LAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQL-SNGFYIPE 380 Query: 446 GTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAM 504 G TL+I + HR D++ P N F+PDNFLPE R Y+++PFS G ++C+G K ++ Sbjct: 381 GVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSL 440 Query: 505 LKLKVILSTILRNFRVISDLKESDFKLQADIILKRAE 541 + K+ L+ ILRN+ + + D + + +K AE Sbjct: 441 ISAKLALAKILRNYMLSTTFLYKDLRFIDNTTMKLAE 477 Score = 54.8 bits (126), Expect = 6e-06 Identities = 57/257 (22%), Positives = 106/257 (41%), Gaps = 11/257 (4%) Query: 30 ILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADI-FRNIVQKSADYDHESV 88 I+ Y+ SRRR Y + KL A E++ I R I+ K + Sbjct: 12 IILCVYFLWSRRRFYIMMLKLPGPMGFPFIGLAFEYIRLKRKIRLRTILFKI----YGKT 67 Query: 89 VKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEY-RFFKPWLGNGLLISTGQKWRSHRK 147 V WIG ++ +P+ +E I +S +++ + LG GLL W RK Sbjct: 68 VLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRK 127 Query: 148 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEILLETAMG-- 203 L+ P+F N + SF+ + N + +V L + + + + +++ + +I + MG Sbjct: 128 LLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWSFKIAAQITMGDE 187 Query: 204 VSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTK 263 V Q+G + + +++ + WLR L K Y K + + + K Sbjct: 188 VRNQANYQNG-NLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNAFIK 246 Query: 264 KVIKRKKEEFASGKKPS 280 +I +K + +P+ Sbjct: 247 DIIDKKLSSTDNSSEPA 263 >UniRef50_Q309A5 Cluster: Cytochrome P450 monooxygenase; n=22; Apocrita|Rep: Cytochrome P450 monooxygenase - Apis mellifera (Honeybee) Length = 499 Score = 132 bits (318), Expect = 3e-29 Identities = 64/198 (32%), Positives = 112/198 (56%), Gaps = 5/198 (2%) Query: 328 FLDLLLESSQS-----GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 F+++L+E ++ + ++D I Q G +T++ S L + ++QD+Q K Sbjct: 270 FINMLMELQKNPQKLENIKLTDSLIAAQAFVFFLAGFETSSTTMSNALYELALNQDVQKK 329 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 + EE++ +++ + + D EM+YL++ ETLR+YPP I+ R+ + T Sbjct: 330 LREEINTFCPKNNKELKYDDIKEMEYLDKVFKETLRMYPPASILMRKAISDYTFNDTKIT 389 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 IP + I + +HR +YPNP+ FDP+ F + A+RH ++PF GPR+C+G ++ Sbjct: 390 IPKEMKIWIPAFAIHRDSAIYPNPDSFDPERFDQDAMASRHPMHYLPFGDGPRNCIGARF 449 Query: 503 AMLKLKVILSTILRNFRV 520 A+ + KV L TILRN +V Sbjct: 450 AVYQTKVGLITILRNHKV 467 Score = 34.7 bits (76), Expect = 6.5 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 3/80 (3%) Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLF---NANSRAVVDKLKKEASNFDCHDYMSECTVEI 196 ++WR R ++P F LK L + N +DKL ++ +C + + T ++ Sbjct: 126 ERWRPLRSRLSPIFTSGKLKEMFYLIIECSLNLETYLDKLIEKNEPIECRELTARFTTDV 185 Query: 197 LLETAMGVSKSTQDQSGFEY 216 + A G+ S+ E+ Sbjct: 186 IGSCAFGIDMSSMTNENSEF 205 >UniRef50_P33270 Cluster: Cytochrome P450 6a2; n=10; Diptera|Rep: Cytochrome P450 6a2 - Drosophila melanogaster (Fruit fly) Length = 506 Score = 132 bits (318), Expect = 3e-29 Identities = 76/238 (31%), Positives = 127/238 (53%), Gaps = 13/238 (5%) Query: 324 KRLAFLDLLLESSQSG-VAISDEEIKE---------QVDTIMFEGHDTTAAGSSFFLSMM 373 KR F++LL+E Q G V + + E+ E QV G +T+++ S+ L + Sbjct: 267 KRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYEL 326 Query: 374 GIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQE 433 +QDIQD++ E+ + + + +T++ M YL + + ETLRLY VP + R+ + Sbjct: 327 AQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALND 386 Query: 434 ITLPSNGKK-IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 492 +P + K I GT ++I HR D+YPNP FDP+ F PE+ A R ++PF Sbjct: 387 YVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGD 446 Query: 493 GPRSCVGRKYAMLKLKVILSTILRNFRV-ISDLKESDFKLQ-ADIILKRAEGFQVRLQ 548 GPR+C+G ++ ++ ++ L+ I+ FRV + D E K I+L G +R++ Sbjct: 447 GPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVE 504 >UniRef50_Q9VYQ7 Cluster: Probable cytochrome P450 311a1; n=2; Drosophila melanogaster|Rep: Probable cytochrome P450 311a1 - Drosophila melanogaster (Fruit fly) Length = 483 Score = 132 bits (318), Expect = 3e-29 Identities = 74/219 (33%), Positives = 121/219 (55%), Gaps = 7/219 (3%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 LD LL + G ++S EI+++++T +F G DTT A SF L + + Q ++ +EL Sbjct: 265 LDTLLLAKFEGQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQ 324 Query: 389 QIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447 + D T D L + YLE + E LRLY VP RQ Q + G+ AG Sbjct: 325 DVALDE---TTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEI--GGRTYCAGV 379 Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGPRSCVGRKYAMLK 506 TL I Y L + YP+P F P+ +LPE A ++++PFS GP C+GR+Y++L Sbjct: 380 TLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLL 439 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQV 545 +K++ + ++R F++ +++ +L+A ++LK +G V Sbjct: 440 MKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINV 478 Score = 81.4 bits (192), Expect = 6e-14 Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 2/192 (1%) Query: 90 KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149 ++ +GP+L VFL+ + L + KA+ + +P +GNGLLIS G W R+L+ Sbjct: 68 RLRLGPQLWVFLHSAEETRQALHDPT-LRKADTFMQLEPLIGNGLLISHGAHWTRQRRLL 126 Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASNF-DCHDYMSECTVEILLETAMGVSKST 208 P F +L+SF + +V +L F + + + C ++ +++T+MG T Sbjct: 127 TPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSMGAQLDT 186 Query: 209 QDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKR 268 Q A +L R L D +F+ T ++ + L +IH + VI++ Sbjct: 187 QSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEK 246 Query: 269 KKEEFASGKKPS 280 + +E +P+ Sbjct: 247 RAKELLDMGEPA 258 >UniRef50_UPI00015B480C Cluster: PREDICTED: similar to cytochrome P450 monooxygenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 monooxygenase - Nasonia vitripennis Length = 730 Score = 131 bits (317), Expect = 4e-29 Identities = 63/197 (31%), Positives = 111/197 (56%), Gaps = 5/197 (2%) Query: 329 LDLLLESSQSGVAISDEEIKE-----QVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383 +D+L++ ++ +DEEI E Q G DTT+ S + + ++ DIQ+K+ Sbjct: 502 VDVLMDIKENPEQFNDEEITELFLTAQAFVFFIAGFDTTSNAMSHAMYELALNPDIQEKL 561 Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443 +E++ + +++ ++ MKYL++ ETLR YPP ++R+ + I Sbjct: 562 RQEVNATYSENNGKFSYDSVRNMKYLDKVFKETLRKYPPAFTLSRKSMNNHSFSGTKITI 621 Query: 444 PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYA 503 P GT+L+I TY +H P YP+P+KFDP+ F + NR + F+PF GPR+C+G ++A Sbjct: 622 PKGTSLMIPTYAIHHDPSYYPDPDKFDPERFDEGNANNRIHMTFLPFGDGPRNCIGERFA 681 Query: 504 MLKLKVILSTILRNFRV 520 + KV ++ +R F++ Sbjct: 682 NNQFKVGIAMTVRKFKL 698 >UniRef50_A7RQ80 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 459 Score = 131 bits (317), Expect = 4e-29 Identities = 58/190 (30%), Positives = 116/190 (61%), Gaps = 3/190 (1%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 L+ +++ +++ EI Q M G++ T + +F + + DIQ+K+ +E+D Sbjct: 239 LEAMIDDETKKKRMTEAEIIAQCLIFMIAGYEGTNSALTFICYNLATNPDIQEKLQQEID 298 Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448 ++ D+D+ +++ E+ YL+ + ETLR+YPP ++ R V Q+ + G++ G Sbjct: 299 SVWTDADQVLSYDILNELSYLDMVVSETLRMYPP-GMLTRAVTQDCVI--QGRRFRKGNA 355 Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508 +++ Y LH P+++P P +F+P+ F E +R+ A++PFSAGPR+CVG ++++++LK Sbjct: 356 ILMDVYSLHHDPELWPEPERFNPERFTAEAKQSRNPCAYLPFSAGPRNCVGMRFSLMELK 415 Query: 509 VILSTILRNF 518 + L+ IL+ + Sbjct: 416 LALTRILKKY 425 Score = 43.6 bits (98), Expect = 0.014 Identities = 48/232 (20%), Positives = 103/232 (44%), Gaps = 18/232 (7%) Query: 61 NALEFVGGSADIFRN---IVQKSADYD--HESVVKIWIGPRLLVFLYDPRDVEVILSS-- 113 N L F+G D ++ I + A+Y + V +++ + + DP ++ +L Sbjct: 5 NHLPFIGTLIDTIKHGGDIRLQFAEYSRTYGRVYGLYLFGSPTIVINDPDILKEVLVKEF 64 Query: 114 HVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV 173 H + D+ + +P+ + + + G+ W R ++P F + +K + L N + ++ Sbjct: 65 HSFHDRPAFFPMPEPF-DSMMFFAEGETWHRVRTTVSPIFSAHKMKMVLPLMNNSCDIMM 123 Query: 174 DKLKKEASN---FDCHDYMSECTVEILLETAMGVSKSTQ---DQSGFEYAMAVMKMCDIL 227 KL++ A F+ + T++ +L G+ S Q D F A + ++ Sbjct: 124 SKLQQAAEKGEPFNMYRMGQSLTMDFILRIVFGIESSVQHNYDDPAFVAARSALEASTFQ 183 Query: 228 HLRHTKIWLRPDLLFK-FTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKK 278 + + + P + K F+ + TK +++ +T+KVI KK + S +K Sbjct: 184 KIAGAVVGMMPKPIKKMFSRVFFSHTK--ELVE-MTEKVIAAKKTQENSTRK 232 >UniRef50_O16156 Cluster: Cytochrome P450 30; n=1; Mercenaria mercenaria|Rep: Cytochrome P450 30 - Mercenaria mercenaria (Northern quahog) (Venus mercenaria) Length = 515 Score = 131 bits (316), Expect = 5e-29 Identities = 70/212 (33%), Positives = 122/212 (57%), Gaps = 5/212 (2%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 ++DEE+ M G+DTTA S+ + + + + Q+K+IEE+D G+S+ T+ Sbjct: 307 LTDEEVLLNSIIFMVAGYDTTATTLSWIVYDLVTNTECQEKLIEEIDAEIGESE--TTYD 364 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 + +++YL+ + ETLR++PP I R +++ + NG +I G + LH P+ Sbjct: 365 NVFKLRYLDMVVNETLRMHPPAQRINRLALEDVKI--NGLQILKGMDCTFSILALHYMPE 422 Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVI 521 + NP K+DP+ F PE AN + YA++PF GPR+C+G++ A+L++K + +L+ FR+ Sbjct: 423 YWENPYKYDPERFAPENQANINQYAYMPFGQGPRNCIGKRLALLEVKATVVVLLQKFRLH 482 Query: 522 SDLKESDFKLQADIIL-KRAEGFQVRLQPRKR 552 K +D+ L K A+ VRL+ R + Sbjct: 483 KTDKLQVPMPVSDVGLGKPAKPVFVRLEKRSK 514 >UniRef50_A1UDQ6 Cluster: Cytochrome P450; n=10; Mycobacterium|Rep: Cytochrome P450 - Mycobacterium sp. (strain KMS) Length = 474 Score = 130 bits (313), Expect = 1e-28 Identities = 67/196 (34%), Positives = 116/196 (59%), Gaps = 7/196 (3%) Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396 ++G ++SD++I ++ M GHDTTA ++ L +G H DIQD+V E + DR Sbjct: 267 ETGRSLSDDDICNELLVFMLAGHDTTATLLTYALWALGHHPDIQDRVAAEACAL---GDR 323 Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456 T D + Y + L E+LRL PP + R +++ + +G ++ AG+ + I Y + Sbjct: 324 LPTPDDVGRLGYTVQVLNESLRLCPPAAGVGRMALRDVEV--DGYRVEAGSLVGIGIYAV 381 Query: 457 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 516 HR P+++ P +FDP+ F PE +R + F+PF+ GPR+C+G+ +AML+ + L+T++R Sbjct: 382 HRDPELWDRPLEFDPERFSPENVKDRDRWQFIPFAGGPRACIGQHFAMLEATLALATLIR 441 Query: 517 NFRVISDLKESDFKLQ 532 + + S + DF L+ Sbjct: 442 SHEIRS--IDDDFPLE 455 >UniRef50_A7RSL1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 510 Score = 130 bits (313), Expect = 1e-28 Identities = 63/199 (31%), Positives = 115/199 (57%), Gaps = 7/199 (3%) Query: 325 RLAFLDLLLESSQS-----GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 R LDL+LE++ S G A+S + I + GH+TT++ +F + + I Sbjct: 282 RKDMLDLMLEAAASDNTDGGKALSLDAIIANTIVFLLAGHETTSSTIAFASYFLAKNPKI 341 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q+K+ +E+D ++ + ++ ++ YLE + ETLRL PP + R+ + + N Sbjct: 342 QEKLQQEIDSVWSGEEEMPSYDTVHDLPYLEMVISETLRLCPPGFAVIRECTKTCII--N 399 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 +IP G+ ++ + Y +HR P YP+P+ FDP+ F PE A+R YA++PF GP +C+G Sbjct: 400 KLRIPQGSRVLASVYSIHRDPKYYPDPDIFDPERFSPEGKASRDPYAYMPFGHGPHNCIG 459 Query: 500 RKYAMLKLKVILSTILRNF 518 ++A +++K++L +L+ + Sbjct: 460 MRFAQMEIKLVLVRMLKRY 478 Score = 41.9 bits (94), Expect = 0.043 Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Query: 126 FKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDC 185 F P L L I G++WR+ R ++P F + LK + L N + K+ A + Sbjct: 123 FSPPLDKMLTILPGEEWRNLRHALSPNFSAHKLKGMVPLMNKACDVYMKKIACAAETGET 182 Query: 186 HDYMS---ECTVEILLETAMGVSKSTQD 210 D M T++I++ A GV Q+ Sbjct: 183 IDVMKINPALTLDIIISCAFGVESDCQN 210 >UniRef50_A3RK60 Cluster: Cytochrome P450; n=2; Liposcelis bostrychophila|Rep: Cytochrome P450 - Liposcelis bostrychophila Length = 527 Score = 130 bits (313), Expect = 1e-28 Identities = 63/190 (33%), Positives = 101/190 (53%) Query: 330 DLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQ 389 +L +E ++S S EE Q G +T++ L + + +IQ+KV E+ Sbjct: 306 ELEVEENRSDQKFSFEEAAAQAFIFFVAGFETSSTTMVLALYELALQPEIQEKVRNEIKT 365 Query: 390 IFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTL 449 + G + +T++ M YL + ETLR YP +I RQ N++ +P + IP GT+ Sbjct: 366 VLGKHNGKITYEAAFGMDYLGNVIDETLRKYPVAGVIIRQCNKDYKIPDSDMVIPKGTST 425 Query: 450 VIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKV 509 I Y LH +PNP KFDPD F E + R YA++PF GPR C+G ++ +++ +V Sbjct: 426 HIPIYSLHYDSKYFPNPEKFDPDRFTEEVKSQRPRYAYLPFGEGPRHCIGMRFGLMQTRV 485 Query: 510 ILSTILRNFR 519 L +L N++ Sbjct: 486 GLIELLLNYK 495 Score = 36.7 bits (81), Expect = 1.6 Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 138 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD---CHDYMSECTV 194 +G KWR+ R + PTF +K + + R ++ L+ A N D D ++ T Sbjct: 129 SGSKWRNLRAKLTPTFTSGKMKMMFPILVESGREMISILEPNAINKDIVEMKDILARFTT 188 Query: 195 EILLETAMGVSKSTQDQSGFEY 216 +++ A G+ ++ E+ Sbjct: 189 DVIASCAFGIDSNSLKNPDTEF 210 >UniRef50_UPI0000D56564 Cluster: PREDICTED: similar to Probable cytochrome P450 6a17 (CYPVIA17); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Probable cytochrome P450 6a17 (CYPVIA17) - Tribolium castaneum Length = 471 Score = 129 bits (312), Expect = 2e-28 Identities = 73/224 (32%), Positives = 122/224 (54%), Gaps = 8/224 (3%) Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380 GQ R FL +L+E + I+ +EI Q + G T+ +F L + HQDIQ Sbjct: 243 GQTGRNDFLQVLVEMEKK-FEITIDEIAAQCFIFLIAGMSTSPTAMTFALYELARHQDIQ 301 Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS-N 439 +KV +++ + FG VT+ EMKYL + ETLR+YPP + R+ + +P + Sbjct: 302 EKVRQDIAK-FGK----VTYDSLQEMKYLGQVFDETLRMYPPAAYLNRKCERNYEIPDGS 356 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G + GT + I +H D YP+P KFDP++F E R +AF+PF GPR C+G Sbjct: 357 GIIVEKGTIVAIPVLGIHYDRDYYPDPEKFDPEHFSEENKRLRPNFAFLPFGEGPRICIG 416 Query: 500 RKYAMLKLKVILSTILRNFR-VISDLKESDFKLQADIILKRAEG 542 ++ +++ K+ L ++L+ ++ +S+ K++ + ++ AEG Sbjct: 417 MRFGLMQSKLGLVSLLKRYKFTVSEKTREPLKMKPNSLVLSAEG 460 >UniRef50_Q29AT3 Cluster: GA11819-PA; n=6; Diptera|Rep: GA11819-PA - Drosophila pseudoobscura (Fruit fly) Length = 513 Score = 129 bits (312), Expect = 2e-28 Identities = 64/210 (30%), Positives = 116/210 (55%), Gaps = 3/210 (1%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 IS E I Q G +TT + ++F L + + ++ +++ E+D+ +D +T+ Sbjct: 303 ISLESITAQAFIFYIAGQETTGSTAAFVLFELAQYPELLERLQTEVDETLAKNDGHITYD 362 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 +M++L+ C+ E+LR YP +P++ R+ Q+ T+P IP GT +VI+ Y +H + Sbjct: 363 ALQKMEFLDLCVQESLRKYPGLPMLNRECTQDYTVPDTDHVIPKGTPVVISLYGIHHDAE 422 Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 520 +P P +DPD + E + N AF+PF GPR C+ ++ +L K+ + +L+NF V Sbjct: 423 YFPEPETYDPDRY-SEENRNFSPTAFMPFGEGPRICIAQRMGLLNAKLAIINVLKNFNVE 481 Query: 521 ISDLKESDFKLQADIILKRAEGFQVRLQPR 550 + ++ +F+ + I L G +VRL R Sbjct: 482 VMSKRQLEFE-NSGIALLPKNGVKVRLSKR 510 >UniRef50_Q964R1 Cluster: Cytochrome P450 6j1; n=1; Blattella germanica|Rep: Cytochrome P450 6j1 - Blattella germanica (German cockroach) Length = 501 Score = 129 bits (311), Expect = 2e-28 Identities = 70/213 (32%), Positives = 112/213 (52%), Gaps = 3/213 (1%) Query: 323 KKRLAFLDLLLESSQSGVAISD-EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 +KR LD L+E S + D ++ Q + G T++ +F L + +HQDIQ Sbjct: 270 EKRNDLLDYLMELRTSETSKLDGDDFVAQAFGFLVAGFHTSSMTLTFALYELSVHQDIQT 329 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 E+ + + VT+ +MKYL+ + ETLR YP +P + R+ ++ L + Sbjct: 330 TARTEIKDVLEHHKKKVTYYSIKDMKYLDMVVNETLRKYPAIPFLDRRCQEDYPLTQD-L 388 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 +PAGT + I Y LH +P+P KFDP+ F + N ++A++PF GPR+C+G + Sbjct: 389 MLPAGTGVYIPVYALHHDSKYFPSPAKFDPERFSEKNKQNIPHFAYMPFGEGPRNCIGMR 448 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQAD 534 + +++K L IL NF V S KE+ L D Sbjct: 449 FGSMQVKAALIHILSNFEV-SPCKETRIPLIID 480 >UniRef50_UPI00015B60B4 Cluster: PREDICTED: similar to cytochrome P450; n=3; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 533 Score = 128 bits (310), Expect = 3e-28 Identities = 62/178 (34%), Positives = 105/178 (58%), Gaps = 2/178 (1%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 IS E Q G +TT++ ++ L + ++ +IQ+KV E+D+ F D +T++ Sbjct: 312 ISLSEAIGQAFIFYLAGFETTSSTITYCLYELALNPEIQEKVQAEIDE-FSKRDGGITYE 370 Query: 402 D-TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 460 + +MKYL +ETLR +P +P + R+ ++ +P+ +I GT L+I +HR P Sbjct: 371 IMSNDMKYLHMVFLETLRKHPSIPFLNRECIEDCDIPNTNFRIEKGTKLLICMNAMHRDP 430 Query: 461 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518 D++P+P KFDP F E A+R Y ++PF GPR+C+G ++ ML+ K+ L +L N+ Sbjct: 431 DIFPDPEKFDPFRFTKENIASRQPYTYLPFGDGPRACIGIRFGMLQTKIALIGLLSNY 488 Score = 41.5 bits (93), Expect = 0.057 Identities = 35/161 (21%), Positives = 64/161 (39%), Gaps = 5/161 (3%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHV--YID 118 NA + G I + QK + V I++ + ++ + DP +++IL + + Sbjct: 54 NAFPLISGKVSIGNLMRQKYNEGKKYPVYGIYMFHKPILLINDPNVIQLILIKEFNKFCN 113 Query: 119 KAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDL---FNANSRAVVDK 175 + + L L G++WR R + PTF LK L N V D+ Sbjct: 114 RGLYFNDKVDTLSLNLFFLPGERWRQLRTKLTPTFTSGKLKQMYPLLLEIGDNLIRVCDQ 173 Query: 176 LKKEASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEY 216 + K+ + + D + T + + A GV + D E+ Sbjct: 174 IIKKDNIVEFKDLIGRYTTDSISSIAFGVDCQSLDNGSSEF 214 >UniRef50_Q0LK65 Cluster: Cytochrome P450; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 454 Score = 128 bits (310), Expect = 3e-28 Identities = 61/182 (33%), Positives = 103/182 (56%), Gaps = 4/182 (2%) Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396 ++G +S ++++ T+ F GH+TTA SF + + D+ +++ E+D + GD+ Sbjct: 246 ETGEPMSTVLLRDEAITVFFAGHETTARTLSFLWYALANNPDVAERMQAEIDSVLGDA-- 303 Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456 T ++ Y + + ETLRLYP P+ AR G K+P G+ + I Y Sbjct: 304 APTLDHLKQLPYTLQVIKETLRLYPAAPMYARDAVASDEFA--GIKVPVGSRMTIMPYLT 361 Query: 457 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 516 HR PD + P +FDPD +LPER A RH +A+ PF+AG R C+G +++ + V+++ + R Sbjct: 362 HRHPDFWDKPLRFDPDRWLPEREALRHPFAYHPFAAGQRICIGNNFSLFESHVVVAMLAR 421 Query: 517 NF 518 +F Sbjct: 422 HF 423 Score = 41.9 bits (94), Expect = 0.043 Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 10/138 (7%) Query: 68 GSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSH--VYIDKAEEYRF 125 G+ F + ++ D H + +G + + + P V ++ Y KA Sbjct: 27 GTLQFFESTWRRYGDLAH-----LQLGSKDMFLVVHPDHVRRVMVEQRDTYSKKASYEGV 81 Query: 126 FKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLF---NANSRAVVDKLKKEASN 182 K LG+GL+ STG WR RKL+AP F +++++ + A R K+ Sbjct: 82 RKLLLGDGLVASTGSLWRRQRKLMAPFFTPRAIETYLPIIVEDGAWFRERWSAAAKQGEP 141 Query: 183 FDCHDYMSECTVEILLET 200 D MS T I+L++ Sbjct: 142 LDILTEMSVLTASIILKS 159 >UniRef50_Q9KFA6 Cluster: Cytochrome P450 hydroxylase; n=1; Bacillus halodurans|Rep: Cytochrome P450 hydroxylase - Bacillus halodurans Length = 453 Score = 128 bits (309), Expect = 4e-28 Identities = 63/213 (29%), Positives = 127/213 (59%), Gaps = 8/213 (3%) Query: 339 GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPV 398 G ++D ++++++ T+ GH+TTA S+ ++ H +++K+ +E+ Q+ G+ RP Sbjct: 248 GSYMTDRQLRDEIITLFLAGHETTANTLSWAFYLLSQHPHVEEKLYQEVSQVLGN--RPA 305 Query: 399 TFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR 458 T +D ++ Y E + ETLR+ P V +I+R+ +++TL I AG+ ++I+ + +HR Sbjct: 306 TLEDMPKLSYAEHVIKETLRVQPTVWLISRRAEKDVTL--GDYHISAGSEIMISQWGMHR 363 Query: 459 RPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRN 517 P + +P F P+ + + + N+ Y + PF GPR C+G ++A+++ +I++TI+R Sbjct: 364 NPRYFNDPLTFLPERW--DNNDNKPSKYVYFPFGGGPRVCIGERFALMEATLIMATIVRE 421 Query: 518 FRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 FR + + E K++ I L+ G ++L+ R Sbjct: 422 FR-MELVDELPIKMEPSITLRPKHGVTMKLRKR 453 Score = 35.1 bits (77), Expect = 4.9 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 1/70 (1%) Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMS 190 GNGLL S G W R+L P FH + + D +++ + D +D M Sbjct: 86 GNGLLTSEGSFWLRQRRLSQPAFHPKRIADYADTMVGYCERMLNTWMDNDTR-DINDEMM 144 Query: 191 ECTVEILLET 200 + T+ I +T Sbjct: 145 QLTMAIATKT 154 >UniRef50_Q9VGB3 Cluster: Probable cytochrome P450 313a3; n=2; Drosophila melanogaster|Rep: Probable cytochrome P450 313a3 - Drosophila melanogaster (Fruit fly) Length = 492 Score = 128 bits (309), Expect = 4e-28 Identities = 73/222 (32%), Positives = 126/222 (56%), Gaps = 4/222 (1%) Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381 Q + + ++ +E ++G +S EE++ + + + +TT L ++ + + QD Sbjct: 263 QPEITSVINKAIELHRNG-EMSREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQD 321 Query: 382 KVIEELDQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440 V +EL ++F + D VT+ D M +LER + ETLRL P VP R+ ++ L S+G Sbjct: 322 TVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRL-SSG 380 Query: 441 KKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 IP G + I + HR D + +P+ F+PD+FLP+ +RH YA++PFS G R+C+G Sbjct: 381 VVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRHPYAYIPFSKGRRNCIG 440 Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAE 541 KY ++ K+ LS ILRN +V + + D + +I ++ A+ Sbjct: 441 WKYGLMSSKLALSKILRNCKVSTSFRYEDLEFVDNIGMELAQ 482 Score = 63.7 bits (148), Expect = 1e-08 Identities = 60/229 (26%), Positives = 99/229 (43%), Gaps = 15/229 (6%) Query: 18 INLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIV 77 ++ F +LL V W Y+ SRRRLY + K+ A E++ + +I Sbjct: 1 MDTFQLLLAVGVCFWI-YFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLI-TYKRKMSIR 58 Query: 78 QKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEY-RFFKPWLGNGLLI 136 K D + S +W+GP V DP+ E I S ++++ + + G+GLL Sbjct: 59 TKYMDI-YGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLS 117 Query: 137 STGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV---DKLKKEASNFDCHDYMSECT 193 KW RK + P F NVL SF+ +FN+ ++ +V D L + D + + Sbjct: 118 LEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEK-KVRDDIVRWS 176 Query: 194 VEILLETAMGVS-------KSTQDQSGFEYAMAVMKMCDILHLRHTKIW 235 I +T +G K+ +E M ++ M +L H KI+ Sbjct: 177 FRIATQTTVGTDVKKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKIF 225 >UniRef50_UPI00015B595F Cluster: PREDICTED: similar to cytochrome P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 538 Score = 128 bits (308), Expect = 5e-28 Identities = 59/173 (34%), Positives = 97/173 (56%), Gaps = 1/173 (0%) Query: 346 EIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLE 405 E QV G +TT+ ++ L + + ++Q+K+ EE+D++ +S + + + Sbjct: 333 EAAAQVFVFFIAGFETTSTTVTYCLHELAKYPEVQEKLQEEIDEV-ANSPEGFNYDNIMN 391 Query: 406 MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPN 465 MKYL+ ETLR +PPVP + R ++ +P +IP G L I+ L R PD+YP Sbjct: 392 MKYLDMTFNETLRKHPPVPFVNRLCTKDYQIPGTDLRIPKGMRLAISVSGLQRDPDIYPE 451 Query: 466 PNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518 P KF+P F E A R Y F+PF GPR C+ ++ A+++ K+ L+T+L + Sbjct: 452 PEKFEPLRFSKENLAQRSAYCFLPFGEGPRICIAKRIALMQGKLALATLLSKY 504 >UniRef50_Q629N7 Cluster: Cytochrome P450-related protein; n=24; Burkholderia|Rep: Cytochrome P450-related protein - Burkholderia mallei (Pseudomonas mallei) Length = 1373 Score = 128 bits (308), Expect = 5e-28 Identities = 69/226 (30%), Positives = 130/226 (57%), Gaps = 8/226 (3%) Query: 329 LDLLLESSQ--SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 + LLL + +G ++ +E+ ++V T+ GH+TT AG ++ L + H + ++ +E Sbjct: 230 ISLLLNARDPDTGAPMTQQEVHDEVMTVFLAGHETTGAGLAWALYALAQHPAVLRQLRDE 289 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 LD G R T QD ++ YL + + E LR+YPP+ R + ++ + G +IPA Sbjct: 290 LDARLGG--RAPTVQDFEQLPYLSQVVDEVLRVYPPIWGFTRDLVEDDEI--GGYRIPAR 345 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 +++ ++ Y HR P + NP+ FDP+NF + A RH + + PF G R C+G + A+L+ Sbjct: 346 SSVFMSPYVTHRHPAFWRNPDAFDPENFASDAPA-RHRFVYFPFGGGMRKCIGFQTALLQ 404 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552 ++V+++ + ++F ++ L +L A I L+ G ++ ++PR+R Sbjct: 405 MRVLVAVVAQHFD-LNALPGHPIELGATISLRPVHGIRLIVKPRER 449 Score = 44.8 bits (101), Expect = 0.006 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Query: 93 IGPRLLVFLYDPRDVEVILS-SHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAP 151 +GP + L P ++ +L +H + Y FK + G+GLL + G+ WR HR+++ P Sbjct: 45 LGPFVTHALAHPDHIQYVLQENHRNYVRGRFYDNFKMFFGDGLLTTDGEFWRRHRRVVQP 104 Query: 152 TFH 154 FH Sbjct: 105 LFH 107 >UniRef50_Q5W1K8 Cluster: Cytochrome P450 CYP6AX1 protein; n=2; Hemiptera|Rep: Cytochrome P450 CYP6AX1 protein - Nilaparvata lugens (Brown planthopper) Length = 514 Score = 127 bits (307), Expect = 7e-28 Identities = 60/186 (32%), Positives = 104/186 (55%), Gaps = 1/186 (0%) Query: 335 SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDS 394 +++S V + D+ + G +TTA +F + + ++Q+IQDK+ +E+ F + Sbjct: 295 NNESHVILDDKLLAANTFIFFIAGFETTATTLTFSMYELAVNQEIQDKLRQEVQTTF-EK 353 Query: 395 DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATY 454 + + T +M YL+R + ETLR YP + R+ + +P K+ G +VI Y Sbjct: 354 YGAINYDSTKDMDYLDRVISETLRKYPIAGSLIRRCTKAWQVPGAKGKLEVGDRVVIPVY 413 Query: 455 KLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTI 514 +H P YP+P KFDP+ F PE +R ++PF GPR C+G ++A+ +LK LS+I Sbjct: 414 PIHHDPKYYPDPQKFDPERFTPENKRSRPPCTYMPFGDGPRICIGARFALQELKTTLSSI 473 Query: 515 LRNFRV 520 L ++++ Sbjct: 474 LLHYKL 479 Score = 38.3 bits (85), Expect = 0.53 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 8/130 (6%) Query: 82 DYDHESVVKIWIGPRL-LVFLYDPRDVEVILSS---HVYIDKAEEYRFFKPWLGNGLLIS 137 DY + W+ R L+ + DP ++ IL H Y D+ L LL Sbjct: 71 DYFADDAYGGWLANRSPLLMVKDPELIQQILVKDFVHFY-DRGTTVDMKLDPLNANLLNM 129 Query: 138 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNA---NSRAVVDKLKKEASNFDCHDYMSECTV 194 TGQ+W++ R+ + P F LK FN + ++D+ + D + MS+ Sbjct: 130 TGQRWKALRQKLTPAFSSGKLKLMSPQFNECVDDLCGLIDEKSNKKELIDVQESMSKLAT 189 Query: 195 EILLETAMGV 204 +++ A G+ Sbjct: 190 DVIGSCAFGL 199 >UniRef50_UPI0000D56E82 Cluster: PREDICTED: similar to Cytochrome P450 9c1 (CYPIXC1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 9c1 (CYPIXC1) - Tribolium castaneum Length = 480 Score = 127 bits (306), Expect = 9e-28 Identities = 71/231 (30%), Positives = 127/231 (54%), Gaps = 13/231 (5%) Query: 329 LDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 + L+LE+++ ++D++I Q T F G +T A SF + IH +IQ K+ E+ Sbjct: 254 IHLMLEANKGQANQLTDDDIVAQAMTFFFAGFETVATACSFMAYELAIHPEIQQKLQAEI 313 Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL-PSN----GKK 442 D + G VT++ L MK+L++ + E+LRL+PP I R + + P N G Sbjct: 314 DSVGG-----VTYESLLSMKFLDQVVSESLRLWPPGFQIERMCTKSYKIEPKNHNEKGIV 368 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 + G +L+I LH PD++P P++FDP+ F + +++PF GPR+C+ ++ Sbjct: 369 LEEGVSLIIPVIALHHDPDLFPEPDRFDPERFSEANRSQIVPGSYLPFGVGPRNCIASRF 428 Query: 503 AMLKLKVILSTILRNFRVIS-DLKESDFKLQA-DIILKRAEGFQVRLQPRK 551 A+L++K + +L F ++ D + KL + L+ +GF++ ++PRK Sbjct: 429 ALLEIKTLFFHMLSKFDIVPIDTTQIPLKLSTKKMHLEPEKGFRLGIRPRK 479 Score = 46.0 bits (104), Expect = 0.003 Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 1/108 (0%) Query: 128 PWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK-KEASNFDCH 186 P LG LL+ GQ W+ R ++P + N LK+ L ++ V K +E D Sbjct: 106 PILGKSLLMLNGQDWKQMRATLSPAYTTNKLKNMHQLMTECAQNFVGHFKGREKVAVDMK 165 Query: 187 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKI 234 D + T +++ TA G+ + +Q + + + ++ KI Sbjct: 166 DIFTRFTTDVIASTAFGIKTDSLNQPNNRFFLMAKSLSKFGFIQVVKI 213 >UniRef50_A0NQ01 Cluster: Cytochrome P450; n=1; Stappia aggregata IAM 12614|Rep: Cytochrome P450 - Stappia aggregata IAM 12614 Length = 476 Score = 127 bits (306), Expect = 9e-28 Identities = 72/222 (32%), Positives = 123/222 (55%), Gaps = 8/222 (3%) Query: 332 LLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390 LLE+ ++G +S + I + I GH+TTA ++ ++ + K+ ELD + Sbjct: 260 LLEARDENGEPLSRDAIISEAAVIFMAGHETTANTLAWAWFLLSQCDKSRAKLQAELDTV 319 Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450 + R TFQD + Y + + ETLRLYPPVPI+AR+ + ++ GK +P G+ ++ Sbjct: 320 L--AGRSPTFQDVPNLPYTKAVIEETLRLYPPVPILAREAMADTSI--GGKSVPKGSLVM 375 Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVI 510 + + +HR P ++ P+ FDP FL +S + Y +VPFS GPR C G ++ M + + Sbjct: 376 VVPWLMHRNPVLWSKPDVFDPGRFLNPKSKKPNKYGYVPFSIGPRICAGLQFGMTEAILS 435 Query: 511 LSTILRNFRVISDLKE-SDFKLQADIILKRAEGFQVRLQPRK 551 L+ + ++F + LKE +D + A + L+ E + L PR+ Sbjct: 436 LAILAQDFEL--KLKEGTDVQPVARLTLRPGENLPMTLHPRR 475 Score = 41.5 bits (93), Expect = 0.057 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 6/116 (5%) Query: 127 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSF--IDLFNANSRAVVDKLKKEASNFD 184 +P LG+GL IS + W RK++AP H + ++ F I + + ++ E + D Sbjct: 104 QPLLGDGLFISDTETWAKRRKVVAPIIHGSRVRGFAPIMIETIEEKRADWAVQGEGAEVD 163 Query: 185 CHDYMSECTVEILLET----AMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWL 236 M+ T EI+ T +G + + GF + DIL L WL Sbjct: 164 ALADMAHLTAEIICRTIFGRQLGKDYAAEVVQGFSDYQRHIDQIDILSLFGLPEWL 219 >UniRef50_Q6PW74 Cluster: Cytochrome P450 CYP331A1; n=1; Capitella capitata|Rep: Cytochrome P450 CYP331A1 - Capitella capitata Length = 549 Score = 127 bits (306), Expect = 9e-28 Identities = 96/403 (23%), Positives = 192/403 (47%), Gaps = 17/403 (4%) Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD-CH--D 187 G + ++ GQ+W+ R + PTF LK +L N SR ++ KL+ A+ D C Sbjct: 117 GCSMFMAQGQRWKRLRTITNPTFTAAKLKHSTELMNRKSRTLLKKLEAIATKGDKCRILP 176 Query: 188 YMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDY 247 + + T++++ E+A G+ + Q+ +G + + + LR + P+L F Sbjct: 177 LLQDLTLDVIGESAFGIEVNAQEIAGNPSLSMLKRNREQNTLRKSFYATLPELRFTIYHC 236 Query: 248 AKNQTKLLDI----IHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLS 303 K + + I KV++ +K + + P +L + +E +T S+E + Sbjct: 237 LAFFAKFVSVPRFQILESMGKVLEMRKIQ--PQRNPPDLMQLMVDAE-ATNHHGSLEIFA 293 Query: 304 FGQSSGLKXXXXXXXXXGQKK-RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTT 362 +++ D + ++ +EIK Q + G++TT Sbjct: 294 DDDDDDDDDDYAKASPDESIDIQISEADRERHARTRKKKLTADEIKSQGFLFLLAGYETT 353 Query: 363 AAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYP- 421 + + + + D Q + EE++ I D D +T++ + YL+ L ETLR+YP Sbjct: 354 SNTLACCSHALANNPDKQQLLYEEVNSIIQD-DEELTYEKVKALPYLDMVLRETLRMYPI 412 Query: 422 PVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY--PNPNKFDPDNFLPERS 479 ++ R+ + T+ N +P + + +H +++ +P F+P+ FLP+R Sbjct: 413 GSQVVTRRCVETCTI--NDLVVPRDMAIHANVWDVHYNANIWGATDPKIFEPERFLPDRK 470 Query: 480 ANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 522 A RH A++PF AGPR+C+G ++A+L+ +++L+ +++ FR++S Sbjct: 471 ARRHPLAWLPFGAGPRNCIGLRFALLEAQIVLAKLIKKFRIVS 513 >UniRef50_Q8WQM9 Cluster: Cytochrome P450 CYP6M1; n=7; Culicidae|Rep: Cytochrome P450 CYP6M1 - Anopheles gambiae (African malaria mosquito) Length = 503 Score = 126 bits (305), Expect = 1e-27 Identities = 60/199 (30%), Positives = 111/199 (55%), Gaps = 4/199 (2%) Query: 324 KRLAFLDLLL----ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 +R F+DL++ ++ A++ E+ Q F G +T++ ++ L + ++ ++ Sbjct: 266 QRNDFMDLMIRMLRDTENPEEALTFNEVAAQAFVFFFAGFETSSTLLTWTLYELALNPEV 325 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q+K + + ++ + +T+ +MKYL++ L E+LR YPPVP+ R Q+ +P Sbjct: 326 QEKGRQCVQEVLAKHNGEMTYDAIHDMKYLDQILKESLRKYPPVPMHFRMTAQDYRVPDT 385 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 I AGT L I + + R ++P P KFDP+ F E A RH +A+ PF GPR C+G Sbjct: 386 DSVIEAGTMLFIPIFSIQRDASLFPEPEKFDPERFSAEEEAKRHPFAWTPFGEGPRVCIG 445 Query: 500 RKYAMLKLKVILSTILRNF 518 ++ M++ ++ L+ +L+ F Sbjct: 446 LRFGMMQARIGLAYLLQGF 464 >UniRef50_Q162V4 Cluster: Cytochrome P450 family protein, putative; n=1; Roseobacter denitrificans OCh 114|Rep: Cytochrome P450 family protein, putative - Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobactersp. (strain OCh 114)) (Roseobacter denitrificans) Length = 451 Score = 126 bits (304), Expect = 2e-27 Identities = 64/195 (32%), Positives = 110/195 (56%), Gaps = 8/195 (4%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 F + + + G S++EI + ++ HDTTA + ++ +G H D Q ++I+E+ Sbjct: 235 FSQMCMAKDEDGKGWSEDEILNHFNLLIMAAHDTTATSLTVIMAALGTHGDWQQRLIDEV 294 Query: 388 DQIFGDSDRPVTFQDTL-EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 D + GD D ++ L +MK ++ E LRL PPVP I R ++ +G IPAG Sbjct: 295 DGL-GDGDLD---EEALGQMKETDKVFREALRLVPPVPFIPRMATRDFHW--HGYDIPAG 348 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCVGRKYAML 505 T+L + P+++ NP +FDPD F P+R+ +R H +A+ PF G C+G +A + Sbjct: 349 TSLALNPGVTMLSPELFSNPTQFDPDRFAPDRAEDRIHRFAWTPFGGGAHKCIGMHFATM 408 Query: 506 KLKVILSTILRNFRV 520 ++K+ ++T+LR R+ Sbjct: 409 QVKLFIATLLRQRRI 423 >UniRef50_Q3IR83 Cluster: Unspecific monooxygenase; n=1; Natronomonas pharaonis DSM 2160|Rep: Unspecific monooxygenase - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 448 Score = 126 bits (304), Expect = 2e-27 Identities = 68/207 (32%), Positives = 116/207 (56%), Gaps = 9/207 (4%) Query: 344 DEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDT 403 + +I+++V T + GH+TTA ++ L ++ H + + +V +E D+ GD P T D Sbjct: 246 ENQIRDEVATFLIAGHETTALSLTYTLCLLSWHPEARRRVRQEADEALGDG--PPTHDDL 303 Query: 404 LEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 463 E+ Y R E LRLYPP + RQ N ++TL IP G+ +++ + +HR + Sbjct: 304 AELTYTRRVYDEALRLYPPAWGVFRQANGDVTL--GQYTIPDGSAVIMPLWSIHRDGSYF 361 Query: 464 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 523 P+ FDPD + ER R A+ PFS+GP +C+GR +A+ ++L+ ++R+F + D Sbjct: 362 EQPDTFDPDRW--ERRTPRAVDAYRPFSSGPHACIGRGFALAGSTLVLARLVRDFDI--D 417 Query: 524 LKESDF-KLQADIILKRAEGFQVRLQP 549 + ES L+ L+ A+G + +QP Sbjct: 418 VPESALDDLRLTPTLRPADGVEATIQP 444 Score = 38.7 bits (86), Expect = 0.40 Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 13/221 (5%) Query: 61 NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120 NAL F D FR + A +D + V I P L+V L P V L + Sbjct: 15 NALRF---GTDTFRFLEGIQARFDDGTSVSIPGRPPLVV-LTGPDLVGEALDRPEDFPRV 70 Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK-LKKE 179 NGL+ S G W R ++AP+F + ++ + A D+ Sbjct: 71 PAQDAVTMIAENGLVQSEGALWSQQRSVMAPSFSGEQVTAYANTTGRRIEARADQWAAAG 130 Query: 180 ASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGF-EYAMAVMKMCDILHLRHTKIWLRP 238 A D H M+ TV + E +G T+ F E+ + + W+ Sbjct: 131 ARTTDLHREMTSLTVRVASEILLGEDIGTERADQFHEWMQVAGEEFEFGIETVLPDWVPT 190 Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKP 279 +F A I L++++I+R++E A+G++P Sbjct: 191 PTSGEFEQAAAG-------IRELSEQLIERRRESLAAGERP 224 >UniRef50_UPI0000DB7C31 Cluster: PREDICTED: similar to Probable cytochrome P450 6a14 (CYPVIA14); n=1; Apis mellifera|Rep: PREDICTED: similar to Probable cytochrome P450 6a14 (CYPVIA14) - Apis mellifera Length = 490 Score = 126 bits (303), Expect = 2e-27 Identities = 65/206 (31%), Positives = 109/206 (52%), Gaps = 3/206 (1%) Query: 346 EIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLE 405 E Q G +T++ +F L + +QDIQ+KV EE+ + + +T+ + Sbjct: 285 EAAAQAYVFFLAGFETSSTTVTFCLYELAKNQDIQNKVREEIQTMI-KKNGDLTYNALND 343 Query: 406 MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPN 465 M YL + + ETLR YPPV I+ R ++ L + IP GT + I + LHR +++PN Sbjct: 344 MNYLHKVISETLRKYPPVVILNRICTNDVKLSTTDFCIPKGTCIAIPVFGLHRDSNIFPN 403 Query: 466 PNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKV-ILSTILRNFRVISDL 524 P KFDP+ F E RH Y ++PF GPR C+G ++ +++ K+ I++ +L+N Sbjct: 404 PEKFDPERFSEENIKTRHPYVYLPFGEGPRICIGLRFGLIQTKIAIINALLKNKFKFGPN 463 Query: 525 KESDFKLQ-ADIILKRAEGFQVRLQP 549 S + + +IL G + ++P Sbjct: 464 TPSTLEFEKGSLILIGKGGIHLNIEP 489 Score = 54.0 bits (124), Expect = 1e-05 Identities = 49/218 (22%), Positives = 91/218 (41%), Gaps = 9/218 (4%) Query: 70 ADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHV--YIDKAEEYRFFK 127 A+ FR+I + + H +V I++ + + + DP + IL+ + D+ Y Sbjct: 40 AEFFRDIYEHNK---HHRLVGIYMLYKPYLIVNDPNLIRDILTKEFTNFHDRGIFYNEEV 96 Query: 128 PWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFD 184 L L G+KWR+ R + PTF +K F + N + L++EA S D Sbjct: 97 DPLSGHLFQLPGKKWRNLRVKLTPTFTSGKIKQFFPILNEAGNILAKYLEEEARKGSTID 156 Query: 185 CHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKF 244 D + + +I++ A G+S + + E+ K+ D L + I P +L F Sbjct: 157 VKDIFARYSTDIIMSVAFGISCDSFKEPNNEFRYWGKKIFDPKPLWNALILFAPQIL-NF 215 Query: 245 TDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNL 282 + + + + K+ +K ++ K NL Sbjct: 216 FSISYTEKSVTKFFTNMFKQTVKYRESNNIERKDFLNL 253 >UniRef50_Q70AR1 Cluster: Putative cytochrome P450; n=1; Streptomyces peucetius|Rep: Putative cytochrome P450 - Streptomyces peucetius Length = 448 Score = 126 bits (303), Expect = 2e-27 Identities = 62/202 (30%), Positives = 118/202 (58%), Gaps = 7/202 (3%) Query: 321 GQKKRLAFLDLLL--ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378 G + L +LL S++G +SD E+++++ TI+F G +TTA+ S+ + H + Sbjct: 222 GTSEHNDLLSVLLGARDSETGEYLSDTEVRDELSTILFAGAETTASTLSWTFYQLAEHPE 281 Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438 ++ +++ E+ + GD RPV+ +D +++ + R L E +RL+ V ++ R+ + L Sbjct: 282 VEAELVAEIKDVVGD--RPVSIEDVPKLEAVRRVLDEVIRLHG-VTMLMRRTTAPVEL-- 336 Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 G +P GT + + Y +HR P +Y +P++FDPD +LPER + A++PF AG R C+ Sbjct: 337 GGHLLPVGTEVGFSLYAMHRDPTLYDDPDRFDPDRWLPERRGDITRQAYIPFGAGNRKCI 396 Query: 499 GRKYAMLKLKVILSTILRNFRV 520 G + + + L+T+L +++ Sbjct: 397 GDAFVWTEATIALATVLARWQL 418 Score = 42.7 bits (96), Expect = 0.025 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 4/83 (4%) Query: 121 EEYRFF---KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK 177 E+ RFF +P G+GL + G+ R HR+LI P FH + + + ++N+ A+ D Sbjct: 73 EKGRFFDRLRPLAGDGLATANGEVHRKHRRLIQPMFHPGRITMYAETMSSNALALADSW- 131 Query: 178 KEASNFDCHDYMSECTVEILLET 200 + M++ +E L T Sbjct: 132 TAGQEVEMEQAMAQFAIETLATT 154 >UniRef50_Q3L917 Cluster: Cytochrome P450; n=1; Rhodococcus erythropolis PR4|Rep: Cytochrome P450 - Rhodococcus erythropolis (strain PR4) Length = 510 Score = 126 bits (303), Expect = 2e-27 Identities = 76/224 (33%), Positives = 120/224 (53%), Gaps = 7/224 (3%) Query: 329 LDLLLESS--QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 LDL+L S+ ++G + I+ QV T + G++TTA +F L + H D+ D E Sbjct: 292 LDLMLHSADAETGEKLDPVNIRNQVFTFLVAGNETTAGTLAFALYFLSRHPDVADTARAE 351 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 + + + P F+D M+YL R + ETLRL+P P R+V + TL +P G Sbjct: 352 VADVTA-GETPA-FEDVARMRYLRRVVDETLRLWPSAPGYFRKVRTDTTLGGR-YDMPKG 408 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 + + + +LHR P +P FDPD F PE R +A+ PF GPR+C+GR++A+ + Sbjct: 409 SWVFVLLPQLHRDPVWGEDPESFDPDRFKPENVKKRPAHAYRPFGTGPRACIGRQFALHE 468 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 + L+ IL+ + SD E ++ + LK GF++ LQ R Sbjct: 469 AVLALAIILQRYNFQSD-PEYKLDIRETLSLKPV-GFELSLQRR 510 >UniRef50_Q5KR92 Cluster: Cytochrome P450; n=1; Hodotermopsis sjoestedti|Rep: Cytochrome P450 - Hodotermopsis sjoestedti Length = 528 Score = 125 bits (302), Expect = 3e-27 Identities = 57/185 (30%), Positives = 102/185 (55%) Query: 336 SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD 395 S + ++ I Q G +T++ +F L + ++ DIQ+++ E+D + Sbjct: 307 SNASFDVTMNVIAAQAFVFYVAGFETSSTTMTFCLYELALNPDIQERLHAEIDTMLEKHG 366 Query: 396 RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYK 455 +T++ EM+YL++ + ETLR YPPV I+ R+ + I L + G +++ Sbjct: 367 GNITYESIFEMEYLDKVVNETLRKYPPVVILTRECTKPIKLRRTDVTLEKGLQVLLPVLG 426 Query: 456 LHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515 LH P YP+P +FDP+ F E R +++F+PF GPR C+G ++A+++ KV L ++L Sbjct: 427 LHHDPKYYPDPERFDPERFSEEEKKKRPHFSFLPFGEGPRMCIGMRFALMQTKVGLISLL 486 Query: 516 RNFRV 520 N+ V Sbjct: 487 SNYEV 491 >UniRef50_A7SCY4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 505 Score = 125 bits (302), Expect = 3e-27 Identities = 62/190 (32%), Positives = 110/190 (57%), Gaps = 3/190 (1%) Query: 332 LLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIF 391 +L S I+DEE+ + T+ G +TTA +F + +G H I+ ++ +E++++ Sbjct: 285 ILRMSDGDKPIADEEMIDNFLTLFIAGQETTANQLAFTVYEIGKHPQIEMRIQDEVERVL 344 Query: 392 GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVI 451 G R V ++D +KY+ + L E+LRL+PP+ ++R ++ITL N IP T +++ Sbjct: 345 GGKSR-VDYEDLNLLKYVNQTLKESLRLHPPISGLSRMTTKDITL--NDVIIPKDTCVIL 401 Query: 452 ATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVIL 511 + + HR P+V+ +P+ FDP+ F E + PFS GPRSC+G A + KVI+ Sbjct: 402 SQFVTHRDPEVWNDPDTFDPERFALENVGRISSSMYFPFSLGPRSCIGNYLAQFEAKVIM 461 Query: 512 STILRNFRVI 521 + + + F+V+ Sbjct: 462 ARLYQQFKVV 471 >UniRef50_Q27594 Cluster: Cytochrome P450 6a9; n=15; Schizophora|Rep: Cytochrome P450 6a9 - Drosophila melanogaster (Fruit fly) Length = 504 Score = 125 bits (302), Expect = 3e-27 Identities = 62/190 (32%), Positives = 108/190 (56%), Gaps = 3/190 (1%) Query: 333 LESSQSG--VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390 L S+SG V ++ EE+ Q G +T++ F L + HQDIQD+V +E ++ Sbjct: 282 LTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEV 341 Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK-KIPAGTTL 449 G + +T++ +M YL++ + ETLRLY +P++ R+ ++ +P + K I G + Sbjct: 342 IGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPV 401 Query: 450 VIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKV 509 +I +HR +Y NPN F+PDNF PER R ++PF GPR+C+G ++ ++ + Sbjct: 402 LIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARS 461 Query: 510 ILSTILRNFR 519 L+ ++ F+ Sbjct: 462 GLALLINRFK 471 >UniRef50_A3RIC1 Cluster: Cytochrome P450; n=1; Bombyx mori|Rep: Cytochrome P450 - Bombyx mori (Silk moth) Length = 489 Score = 125 bits (301), Expect = 4e-27 Identities = 64/189 (33%), Positives = 100/189 (52%), Gaps = 1/189 (0%) Query: 343 SDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQD 402 +DE + Q G DTTA F L + + + K+ E+D++F D + + F+D Sbjct: 281 TDELLAAQAFFFFVAGADTTANVMHFTLLELSSNPSVLKKLHAEIDEVFQDGKKTLNFED 340 Query: 403 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDV 462 + KYLE + ET+R YPP+ ++ R +E LPSN +I T V+ LHR Sbjct: 341 MDKFKYLEMVVNETMRKYPPIGLLQRICTKETNLPSNNLRISKDTIAVVPVLALHRDERF 400 Query: 463 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVI- 521 YP + FDP F PE + ++F+PF G R C+G K+A L+L+ L+ +LR + ++ Sbjct: 401 YPKSDAFDPQRFAPENFNEINKFSFLPFGEGNRVCIGAKFARLQLRAGLAWLLRKYTLVP 460 Query: 522 SDLKESDFK 530 D K F+ Sbjct: 461 QDYKPVKFE 469 >UniRef50_Q8MZK0 Cluster: Cytochrome P450; n=6; Culicidae|Rep: Cytochrome P450 - Anopheles gambiae (African malaria mosquito) Length = 505 Score = 124 bits (300), Expect = 5e-27 Identities = 62/210 (29%), Positives = 111/210 (52%), Gaps = 1/210 (0%) Query: 334 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 393 E+++ ++ +E+ Q F G +T++ SF L + + DIQ++V E+ + Sbjct: 287 ETTEGLQKLTLDEVAAQAFVFFFAGFETSSTTLSFALFELANNPDIQERVRAEMLEKLQL 346 Query: 394 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIAT 453 D +T+ EM YL++ + ETLR+YPPVP + R Q + + T L+I Sbjct: 347 HDGKITYDALKEMTYLDQVINETLRMYPPVPQLIRVTTQPYKVEGANVSLEPDTMLMIPI 406 Query: 454 YKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILST 513 Y +H +YP+P +FDPD F + RH +AF+PF GPR+C+G ++ +L++K + Sbjct: 407 YAIHHDASIYPDPERFDPDRFALAATHARHTHAFLPFGDGPRNCIGMRFGLLEVKFGIVQ 466 Query: 514 ILRNFR-VISDLKESDFKLQADIILKRAEG 542 ++ R +S+ + ++ + AEG Sbjct: 467 MVSKLRFTVSERMQMPLRMSKTASILEAEG 496 >UniRef50_UPI0000D576F6 Cluster: PREDICTED: similar to Probable cytochrome P450 6a20 (CYPVIA20); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Probable cytochrome P450 6a20 (CYPVIA20) - Tribolium castaneum Length = 487 Score = 124 bits (298), Expect = 8e-27 Identities = 59/202 (29%), Positives = 110/202 (54%), Gaps = 2/202 (0%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 +S EI Q ++T+ +F L + + DIQD+V E+ + + +++ Sbjct: 277 MSINEIIAQCFIFFIAAYETSTTTLTFALYELAQNLDIQDRVRREITSVLLKHQK-YSYE 335 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 EMKYL + + ET+R YPP + R+ ++ T+P I G +I+ +H + Sbjct: 336 AIAEMKYLNQIVDETMRKYPPFLYVVRRCTKDYTIPGEDVTIKKGIFALISILGIHHDEE 395 Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR-V 520 +YPNP KFDPD F E RH YA++PF GPR C+G+++A++++K L+ +L ++ Sbjct: 396 IYPNPQKFDPDRFSKENKKMRHPYAYLPFGEGPRICIGKRFALMQIKFGLAALLEKYKFT 455 Query: 521 ISDLKESDFKLQADIILKRAEG 542 +++ + +++ D ++ +G Sbjct: 456 LNEKTKVPLEIRTDTLVVAPKG 477 >UniRef50_Q9V4U7 Cluster: Probable cytochrome P450 6a14; n=10; Schizophora|Rep: Probable cytochrome P450 6a14 - Drosophila melanogaster (Fruit fly) Length = 509 Score = 124 bits (298), Expect = 8e-27 Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 1/176 (0%) Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404 E++ Q G +T+++ S L + + DIQ ++ EE++ + + D D L Sbjct: 301 EQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVL 360 Query: 405 -EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 463 +M YL++ L ETLR +P +P + R+ ++ +P++ + G +I + +H P++Y Sbjct: 361 AQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIY 420 Query: 464 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519 P P KFDP F PE NRH A++PF GPR+C+G ++ ++ K+ L ++LR F+ Sbjct: 421 PEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFK 476 >UniRef50_Q1IM54 Cluster: Cytochrome P450; n=1; Acidobacteria bacterium Ellin345|Rep: Cytochrome P450 - Acidobacteria bacterium (strain Ellin345) Length = 460 Score = 123 bits (297), Expect = 1e-26 Identities = 62/206 (30%), Positives = 120/206 (58%), Gaps = 5/206 (2%) Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404 E++++QV TI G++TTA S+ ++G + +++ +V+ E+D + + R + +D Sbjct: 259 EQLRDQVVTIFLAGYETTANALSWTFRLLGENPEVERRVLAEVDDVL--NGRMASVEDVP 316 Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464 ++KY+E L E++RLYPP + RQ + L +P GTT++++ + +HR + + Sbjct: 317 QLKYIEMVLAESMRLYPPAWAMVRQGINDFQL--GDYFLPGGTTVMMSQWVMHRSEEFWL 374 Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDL 524 +P +FDP+ F PE A R +A+ PF G R C+G +A ++ ++L+T+++ +R + Sbjct: 375 DPLRFDPERFRPEAKAGRPKFAYFPFGGGGRQCIGEAFAWMEGALLLATLVQKYR-FRLV 433 Query: 525 KESDFKLQADIILKRAEGFQVRLQPR 550 F+ Q+ I L+ G +V + R Sbjct: 434 AGQTFEPQSLITLRPRNGVRVVAEAR 459 Score = 47.6 bits (108), Expect = 9e-04 Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Query: 84 DHESVVKIWIGPRLLVFLYDPRDV-EVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKW 142 D+ V +G + +VFL D + EV++ + K E R K LGNG++ + Q W Sbjct: 49 DYGKVGGYRVGNKRVVFLADAELIREVLVVQNDNFVKGEPVRRTKVLLGNGMITAEQQDW 108 Query: 143 RSHRKLIAPTFHLNVLKSFID 163 RS R+ P FH ++S+ D Sbjct: 109 RSQRQAAQPAFHRQRIRSYAD 129 >UniRef50_A7LFI0 Cluster: Cytochrome P450; n=3; Tribolium castaneum|Rep: Cytochrome P450 - Tribolium castaneum (Red flour beetle) Length = 493 Score = 123 bits (297), Expect = 1e-26 Identities = 57/177 (32%), Positives = 104/177 (58%), Gaps = 3/177 (1%) Query: 344 DEEIKEQVDTIMF--EGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 D +IK I F G+DTT+ + + +++ IQD++ E+ +I+ ++ T++ Sbjct: 283 DNDIKMAAQAIAFFSAGNDTTSITLALTCYELSLNKTIQDRLRHEVTEIYNENGE-FTYE 341 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 + L MKYL+ + ETLR YP P + R+ + + T G + G ++++ LH P+ Sbjct: 342 NILGMKYLDMVISETLRKYPLAPFLNRKSDVKYTFEETGFTLDKGVSIMVPISGLHYDPE 401 Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518 YP+P K+DP+ F E N Y ++PF GPR+C+G+++A+L KV L++++++F Sbjct: 402 YYPDPEKYDPERFSDENKKNLTPYTYLPFGEGPRNCIGQRFALLVSKVALASVVKDF 458 >UniRef50_Q0LL77 Cluster: Cytochrome P450; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 446 Score = 123 bits (296), Expect = 1e-26 Identities = 63/195 (32%), Positives = 111/195 (56%), Gaps = 6/195 (3%) Query: 329 LDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 L +LL++ G ++D ++++++ T+ GH+TTA ++ ++ H I K+ +E Sbjct: 228 LSVLLQAHDDDDGSFMTDTQVRDELMTLFLAGHETTANALTWTWYLLAHHPHIATKIKDE 287 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 +D G R T D ++ Y + E+LRLYPPV +IAR+ +Q L S +P G Sbjct: 288 VDSTVGT--RLPTMDDLSKLPYTLQVFKESLRLYPPVYMIARKASQAFELGSY--HVPEG 343 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 V++ Y +HRR D + +P F+PD F A+ A++PFS GPR+C+G +AM++ Sbjct: 344 MAFVVSPYTIHRRADYFDHPEDFNPDRFDTSHEASIPKNAYIPFSLGPRNCIGNHFAMME 403 Query: 507 LKVILSTILRNFRVI 521 ++L+ I + R++ Sbjct: 404 GHLMLAIIAQRMRLL 418 Score = 42.3 bits (95), Expect = 0.032 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 3/127 (2%) Query: 85 HESVVKIWIGPRLLVFLYDPRDVEVILSSHVY-IDKAEEYR-FFKPWLGNGLLISTGQKW 142 H + ++G +VF+ IL H ++K+ R + +P LGNGLL S Sbjct: 37 HGDLGVFYLGSYPVVFINSAEYAHGILVQHAQSVEKSLMLRKYMRPLLGNGLLTSENSFH 96 Query: 143 RSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAM 202 R RKL+AP F + ++ + +A + + + D M T+ ++ +T Sbjct: 97 RRQRKLVAPAFQHRHIANYANTISAYTDETQARW-HQGQRIDIAQEMMRLTLRVMSQTLF 155 Query: 203 GVSKSTQ 209 +T+ Sbjct: 156 STDINTE 162 >UniRef50_A7SRX7 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 472 Score = 123 bits (296), Expect = 1e-26 Identities = 58/199 (29%), Positives = 110/199 (55%), Gaps = 5/199 (2%) Query: 323 KKRLAFLDLLLESS---QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 K+ LDL+L ++ + +SD E+ Q + G++TT SF + + D+ Sbjct: 274 KEAKDMLDLMLSAAANENTSKKLSDMEVLAQSLIFLIAGYETTNITLSFVAYSLATNPDV 333 Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439 Q+K+ E+D ++ + D+ ++ + YL+ + ETLRLYPP + +R+ Q+ + Sbjct: 334 QEKLQREIDSVWTEEDQMPSYDTVHNLPYLDMVISETLRLYPPGFVASRECTQDCVI--K 391 Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499 G + G ++ I Y +H P+ + +P +FDP+ F E +R Y+++PF GP +C+G Sbjct: 392 GYRFRKGLSIFIDAYSMHHDPEFWTDPERFDPERFSRECKQSRDPYSYLPFGHGPHNCIG 451 Query: 500 RKYAMLKLKVILSTILRNF 518 ++A +++K+ L +LR F Sbjct: 452 MRFAQMEIKLALVRVLRKF 470 Score = 51.2 bits (117), Expect = 7e-05 Identities = 43/170 (25%), Positives = 76/170 (44%), Gaps = 7/170 (4%) Query: 141 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSECTVEIL 197 KW R ++P F + +K + L N++ +++KL K A ++F H + T++ + Sbjct: 134 KWHRIRTSLSPAFSAHKMKLMVPLINSSCDVLINKLTKIADSGTSFFVHKFHQGLTMDTI 193 Query: 198 LETAMGVSKSTQ---DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKL 254 L+TA G+ Q D F A M + I+L P + F + Sbjct: 194 LKTAFGIHSEAQTNYDDPAFTAARKSMSTSPARRVMLFLIFLMPFRKYIFRWFPSLLIGN 253 Query: 255 LDIIHGLTKKVIKRKK-EEFASGKKPSNLNETATTSEPSTGKLTSVEGLS 303 D I +T K+I+ KK K +L +A +E ++ KL+ +E L+ Sbjct: 254 FDDIMKITTKMIEVKKVNPHKEAKDMLDLMLSAAANENTSKKLSDMEVLA 303 >UniRef50_Q964T2 Cluster: Cytochrome P450 9e2; n=2; Blattaria|Rep: Cytochrome P450 9e2 - Blattella germanica (German cockroach) Length = 533 Score = 122 bits (295), Expect = 2e-26 Identities = 56/178 (31%), Positives = 97/178 (54%), Gaps = 1/178 (0%) Query: 344 DEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDT 403 D+++ Q F G DT + F ++ + D+Q+++ +E+DQ ++D +T++ Sbjct: 321 DDDLTAQAVLFFFAGFDTASTLLCFMSHLLATNPDVQNRLQDEIDQSLEENDGKLTYEAI 380 Query: 404 LEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK-KIPAGTTLVIATYKLHRRPDV 462 MKYL+ + E+LRLYPP R+ + LP + G + I Y +H P Sbjct: 381 HSMKYLDMVVSESLRLYPPAIFTDRKCVKNYRLPMEPSYTLEPGDAVWIPIYAIHHDPKY 440 Query: 463 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520 YPNP KFDP+ F E N + ++PF +GPR+C+G ++A+++ K+ L +L F + Sbjct: 441 YPNPEKFDPERFSDENKDNIKPFTYLPFGSGPRNCIGNRFALMESKIALVHLLCRFNL 498 >UniRef50_Q9V769 Cluster: Cytochrome P450 6a22; n=2; Sophophora|Rep: Cytochrome P450 6a22 - Drosophila melanogaster (Fruit fly) Length = 499 Score = 122 bits (295), Expect = 2e-26 Identities = 74/235 (31%), Positives = 127/235 (54%), Gaps = 8/235 (3%) Query: 325 RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVI 384 R F++LL+E Q G ++ EE+ Q G DT+A+ F L + +Q K+ Sbjct: 267 RSDFMNLLIEMKQRG-ELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLR 325 Query: 385 EELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK-- 442 EE+DQ + T+ E++Y+E + ETLR YP +P + R +++ + + Sbjct: 326 EEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTR-ISRHLYAAKGDRHFY 384 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 I G L+I Y +H P +YP P+KF P+ FL ++ A R A++PF GPR+C+G ++ Sbjct: 385 IEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRF 444 Query: 503 AMLKLKVILSTILRNFRVISDLKESDFK---LQADIILKRAEGFQVRLQPRKRMA 554 ++ + L ++LRNF S +D K L+++I+L A G +++Q +M+ Sbjct: 445 GKMQTTIGLVSLLRNFH-FSVCPRTDPKIEFLKSNILLCPANGIYLKVQQLSQMS 498 >UniRef50_Q825N1 Cluster: Cytochrome P450 hydroxylase; n=6; Actinomycetales|Rep: Cytochrome P450 hydroxylase - Streptomyces avermitilis Length = 504 Score = 122 bits (294), Expect = 3e-26 Identities = 68/226 (30%), Positives = 125/226 (55%), Gaps = 9/226 (3%) Query: 329 LDLLLESSQSGVA--ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 LD +L++++ G ++ E I+ QV T + GH+TT+ SF L + H D+ + E Sbjct: 257 LDRMLDTARPGTGERLAPENIRRQVITFLVAGHETTSGALSFALHYLSRHPDVAARARAE 316 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 +D+++G + RP + +++Y+ R L E+LRL+P P AR+ ++ L + G Sbjct: 317 VDRVWGGTARP-GYDQVAKLRYVRRVLDESLRLWPTAPAFAREARRDTVL-GGVHPMREG 374 Query: 447 TTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505 ++ T LHR P V+ + +FDPD F + +R + F PF G R+C+GR++A+ Sbjct: 375 AWALVLTAMLHRDPGVWGADAERFDPDRFDAQAVRSRAAHTFKPFGTGARACIGRQFALH 434 Query: 506 KLKVILSTILRNFRVISDLKESDFKLQ-ADIILKRAEGFQVRLQPR 550 + ++L +LR + + + E ++L+ A+ + EG ++RL R Sbjct: 435 EATLVLGLLLRRYELRA---EPGYRLRVAERLTLMPEGLRLRLDRR 477 >UniRef50_Q0LFI0 Cluster: Cytochrome P450; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 457 Score = 122 bits (294), Expect = 3e-26 Identities = 64/193 (33%), Positives = 110/193 (56%), Gaps = 7/193 (3%) Query: 329 LDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 LD+LLE+ +++G +SDE+I+++V TI GH+TTA +F ++ H +I+ + E Sbjct: 238 LDMLLEAQDAETGERMSDEQIRDEVLTIFAAGHETTANTLTFGWYLLSEHCEIRQNLQTE 297 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIA-RQVNQEITLPSNGKKIPA 445 LDQ+ R + D ++ Y + E +RLYP PI R+V + L G +P Sbjct: 298 LDQVL--QGRAPSVNDLPQLPYTLQVFKEAMRLYPAAPITGPRRVTKPTQL--GGYDLPL 353 Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505 + ++++ LH P + NP +FDP F P + RH+ AF+PF AGPR C+G A + Sbjct: 354 NSQVIVSITNLHLHPAFWENPLQFDPSRFAPNANQPRHHLAFMPFGAGPRKCIGNNLAEM 413 Query: 506 KLKVILSTILRNF 518 + ++L+ + +++ Sbjct: 414 EGALLLACVAQHY 426 >UniRef50_A7T1A2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 523 Score = 122 bits (294), Expect = 3e-26 Identities = 62/199 (31%), Positives = 109/199 (54%), Gaps = 4/199 (2%) Query: 325 RLAFLDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382 R F+DL+L + +SD EI Q T + GH+T++ S + ++ ++Q++ Sbjct: 297 RKDFVDLMLSAVNPDGSRKLSDPEIIAQSVTFLLAGHETSSNTLSATAYYLALNPEVQER 356 Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 + E+ + + +++YL+ + E LR++PP I R+ Q + NG Sbjct: 357 LRLEIRMAAETNSEKSPQELANDLEYLDCVVNEVLRIHPPAHTINRECAQACVI--NGIT 414 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502 IPAG + I Y LH PD +P P+KFDP+ F +RH + F+PF AGPR+C+G ++ Sbjct: 415 IPAGMDVTIPIYSLHHDPDAWPEPDKFDPERFRGPAKESRHPFQFIPFGAGPRNCIGMRF 474 Query: 503 AMLKLKVILSTILRNFRVI 521 A+ ++K++L IL ++ + Sbjct: 475 ALNEVKLVLFQILSKYKFV 493 >UniRef50_Q9GQM9 Cluster: Cytochrome P450 6l1; n=1; Blattella germanica|Rep: Cytochrome P450 6l1 - Blattella germanica (German cockroach) Length = 503 Score = 122 bits (294), Expect = 3e-26 Identities = 53/192 (27%), Positives = 106/192 (55%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 +D L++ + + +S+ E+ Q G +TT++ +F + + +H +IQD++ E+ Sbjct: 270 VDSLIQLKKQLIDVSEHEVLGQAMLFFAAGFETTSSAMAFAMYELALHPEIQDRLRTEIQ 329 Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448 ++ VT++ +M YL+ + E LR YPP+ I R + +P I GT Sbjct: 330 EVTACHGGQVTYEGVKKMSYLDMVVSEVLRKYPPMSFIDRVCLHDYHIPGTDVVIEKGTP 389 Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508 + ++ LHR YP+P F+P+ F E+ + H ++++PF GPR+C+G + ++ +K Sbjct: 390 IFVSLLGLHRDSIFYPDPEDFNPERFNKEKKSGVHPFSYIPFGDGPRNCIGLRLGLMSVK 449 Query: 509 VILSTILRNFRV 520 +++ +L++ RV Sbjct: 450 LVIIMLLQSLRV 461 >UniRef50_UPI0000D5650B Cluster: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a2 (CYPVIA2) (P450-B1) - Tribolium castaneum Length = 485 Score = 122 bits (293), Expect = 3e-26 Identities = 60/204 (29%), Positives = 109/204 (53%), Gaps = 4/204 (1%) Query: 325 RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVI 384 R F+ LL+E + ++ EEI Q G +T++A +F L + +Q++Q+ Sbjct: 262 RSDFMQLLIEMKKQN-QLTIEEIAAQCFVFFIAGFETSSATLTFALYELAKNQNLQNVA- 319 Query: 385 EELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIP 444 D+I + +T+ ++K+L++ + ETLR YPP+ + RQ + +P I Sbjct: 320 --RDEILANCPNEITYDSLADLKFLDQVVDETLRKYPPLLYVTRQCVKNYKIPDEDVVIE 377 Query: 445 AGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAM 504 GT + I LH + YP P F+P+ F + RH Y F+PF GPR C+G+++ + Sbjct: 378 KGTLVAIPISALHSDEEFYPKPETFEPERFSKTEKSLRHPYTFLPFGEGPRMCIGKRFGL 437 Query: 505 LKLKVILSTILRNFRVISDLKESD 528 L++K+ L+ +L+N++ + K + Sbjct: 438 LEVKLALTCLLKNYKFSVNCKTKE 461 >UniRef50_UPI00015B4FBC Cluster: PREDICTED: similar to cytochrome P450 monooxygenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 monooxygenase - Nasonia vitripennis Length = 568 Score = 121 bits (292), Expect = 4e-26 Identities = 62/202 (30%), Positives = 107/202 (52%), Gaps = 5/202 (2%) Query: 324 KRLAFLDLLLE-----SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378 +R F+DLL++ S + ++D I Q G +T++ S L + ++ Sbjct: 335 RRNDFVDLLMDIKDDPSKVGDIEMTDALITAQAFVFFIAGFETSSTTISNALYELALNPS 394 Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438 +Q+K+ EE+ + + + + ++ MKYL + ETLR YPPV ++ R+ Q T Sbjct: 395 VQEKLREEIIEELANDNGSLKYETIKGMKYLHKVFCETLRKYPPVTVMMRKSMQPYTFSG 454 Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 IP G + I Y + R P +YP+P+ FDP+ F E RH ++PF GPR+C+ Sbjct: 455 TKVTIPKGMRVWIPAYAIQRDPAIYPDPDTFDPERFSEESIKQRHPSFYLPFGDGPRNCI 514 Query: 499 GRKYAMLKLKVILSTILRNFRV 520 G ++A + K+ + +LRN++V Sbjct: 515 GARFANYQSKIGIIQVLRNYKV 536 >UniRef50_Q0LJ67 Cluster: Cytochrome P450; n=2; cellular organisms|Rep: Cytochrome P450 - Herpetosiphon aurantiacus ATCC 23779 Length = 1053 Score = 121 bits (292), Expect = 4e-26 Identities = 72/230 (31%), Positives = 118/230 (51%), Gaps = 8/230 (3%) Query: 329 LDLLLESSQS--GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 L L+L + S G + D I+ Q+ T + GH+TT+ SF + +I + Sbjct: 241 LGLMLNAKDSITGEGLDDANIRNQLVTFLIAGHETTSGLLSFATYFLLQQPEILQRAQAI 300 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 +DQ+ GD R ++D ++ YL++ L ETLRL+P P+ + + G I G Sbjct: 301 VDQVLGD--RLPRYEDLAKLGYLDQILRETLRLWPTAPVFGVYAKHDTNI--GGFPIKQG 356 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 + LHR P V+ NPN+FDPD F PE +A+ PF G R+C+GR +AM + Sbjct: 357 EKFIALLPTLHRDPKVWLNPNQFDPDRFAPEVREQIPEHAWKPFGNGQRACIGRSFAMQE 416 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRMAKA 556 ++L+ +L+ F +S + ++ + LK EG VR + RK + ++ Sbjct: 417 ASLVLAMMLQRFE-LSQPQPYQLHVKETLTLK-PEGLTVRARVRKNIVRS 464 >UniRef50_Q27691 Cluster: Cytochrome P450; n=2; Musca domestica|Rep: Cytochrome P450 - Musca domestica (House fly) Length = 503 Score = 121 bits (292), Expect = 4e-26 Identities = 58/194 (29%), Positives = 109/194 (56%), Gaps = 2/194 (1%) Query: 328 FLDLLLE--SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIE 385 F+DLL+E + + +S E++ G +T++ +F L + + +IQ+K+ Sbjct: 273 FMDLLMEIRAKEGEEGLSFEQMAALTFDFFLAGFETSSTTMAFTLYELARNPEIQEKLRT 332 Query: 386 ELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445 E+ I DS+ ++++ +M +LE+ + ETLRLYP + + R N++ +P + I Sbjct: 333 EILDILKDSNDELSYEALQKMSFLEQSISETLRLYPVLATLVRVANRDYPVPDSQHIIEK 392 Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505 +VI + +H P+ Y NP +F+P+ F E RH ++PF GPRSC+G ++ + Sbjct: 393 DIQVVIPVHAIHHDPEYYENPEEFNPNRFAAEECERRHSSTYLPFGDGPRSCIGMRFGKM 452 Query: 506 KLKVILSTILRNFR 519 + K+ L ++LR++R Sbjct: 453 QTKIGLVSLLRHYR 466 >UniRef50_P29980 Cluster: Probable cytochrome P450 110; n=2; Nostocaceae|Rep: Probable cytochrome P450 110 - Anabaena sp. (strain PCC 7120) Length = 459 Score = 121 bits (292), Expect = 4e-26 Identities = 58/190 (30%), Positives = 118/190 (62%), Gaps = 8/190 (4%) Query: 331 LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390 ++ ++G A++DEE+K+++ TI+F GH+TTA ++ + + ++Q+K+ +ELD++ Sbjct: 235 MMAARDENGQAMTDEELKDELLTILFAGHETTATTIAWAFYQILKNVNVQEKLQQELDRL 294 Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450 G + P+ + ++ YL ETLR+YP +P + ++ + ++ G ++ TTL+ Sbjct: 295 -GANPNPM---EIAQLPYLTAVSQETLRMYPVLPTLFPRITKS-SINIAGYQLEPDTTLM 349 Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVI 510 + Y +H R D+YPNP +F P+ F+ + + Y +PF G R C+G A+L++K++ Sbjct: 350 ASIYLIHYREDLYPNPQQFRPERFIERQYSPSEY---IPFGGGSRRCLGYALALLEIKLV 406 Query: 511 LSTILRNFRV 520 ++T+L N+++ Sbjct: 407 IATVLSNYQL 416 >UniRef50_Q16F55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 543 Score = 121 bits (291), Expect = 6e-26 Identities = 60/175 (34%), Positives = 96/175 (54%), Gaps = 6/175 (3%) Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404 EE+ + + G + + +F L + + IQ ++ +E+ D+D +T+ + Sbjct: 340 EELTTACYSFVKHGMEPCTSVMTFCLYELAKNVSIQKRLRDEISHYLEDTDGQLTYDVIM 399 Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464 M YL++ + ET+R YPPV I R+ +Q + IP GT VI Y H PD +P Sbjct: 400 SMNYLDQVVNETMRKYPPVDFIYRRSSQ------SRDNIPQGTLFVIPVYAFHHDPDHFP 453 Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519 P KFDP+ F +++ RH Y ++PF AGPR C+G ++ +L +K L T+LR FR Sbjct: 454 APEKFDPERFTAKQARTRHPYCYLPFGAGPRECLGARFGLLVVKAGLVTLLRRFR 508 >UniRef50_Q069I9 Cluster: Gossypol-induced cytochrome P450; n=9; Ditrysia|Rep: Gossypol-induced cytochrome P450 - Helicoverpa armigera (Cotton bollworm) (Heliothis armigera) Length = 526 Score = 120 bits (290), Expect = 8e-26 Identities = 54/179 (30%), Positives = 98/179 (54%), Gaps = 1/179 (0%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 + D+ + Q G++T+A SF L + H + Q + I E+D + + ++ Sbjct: 302 VDDDLLVAQCFIFFAAGYETSATTLSFTLYELAKHPEAQKRAIAEVDDYLRRHNNELKYE 361 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 EM ++E C ETLR YP + ++ R+V ++ T PS G K+ G + + Y LH P+ Sbjct: 362 CLSEMPFVEACFDETLRKYPVLSLLTREVVEDYTFPS-GLKVEKGLRIFLPLYHLHHNPE 420 Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520 +P+P ++ P+ FLPE Y ++PF GPR C+G ++A +++ + T+L+ +R+ Sbjct: 421 FFPDPEEYRPERFLPENKDKIKPYTYMPFGEGPRLCIGMRFAKMQMTAGIITLLKKYRL 479 Score = 38.3 bits (85), Expect = 0.53 Identities = 26/126 (20%), Positives = 53/126 (42%), Gaps = 4/126 (3%) Query: 89 VKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFF--KPWLGNGLLISTGQKWRSHR 146 V + G + + DP ++++++ Y + E + + L ++G KW+ R Sbjct: 72 VGAYFGTEPALIVQDPEHIKLVMTKDFYFFSSREISEYADRERFTQNLFSTSGNKWKVLR 131 Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SNFDCHDYMSECTVEILLETAMGV 204 + + P F +K+ L S D L KEA + + ++ T++ + A GV Sbjct: 132 QNLTPVFTSAKMKNMFHLIEKCSHVFEDFLDKEAKSNEVEMRALVARYTMDCIGTCAFGV 191 Query: 205 SKSTQD 210 T + Sbjct: 192 ETKTMN 197 >UniRef50_UPI0000DB6FEA Cluster: PREDICTED: similar to Probable cytochrome P450 6a14 (CYPVIA14); n=1; Apis mellifera|Rep: PREDICTED: similar to Probable cytochrome P450 6a14 (CYPVIA14) - Apis mellifera Length = 497 Score = 120 bits (288), Expect = 1e-25 Identities = 60/192 (31%), Positives = 96/192 (50%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 +D+L + ++ + + Q G + + S L + +IQ+K E+ Sbjct: 271 IDILADIRENPTKSDNLFLTSQAVLFFLAGFENASLTISNALYELAWKPEIQEKARAEIV 330 Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448 + D +T+ EMKYLE C+ ETLR+YP + ++R+ + T IP G Sbjct: 331 NVLQKYDGKITYDGLEEMKYLEACIFETLRMYPVLQWLSREAMETYTFTGTKVTIPKGQQ 390 Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508 + + Y + R PD+YPNP+ FDP+ F ++ RH +PF GPR C G + A +LK Sbjct: 391 VFLPIYAIQRDPDIYPNPDNFDPERFTDDKIKTRHSMTHLPFGDGPRHCSGIRLAKKQLK 450 Query: 509 VILSTILRNFRV 520 V L T+L F+V Sbjct: 451 VGLVTVLSKFKV 462 >UniRef50_UPI0000D577ED Cluster: PREDICTED: similar to Cytochrome P450 6g1 (CYPVIG1) (Cyp6-like protein); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Cytochrome P450 6g1 (CYPVIG1) (Cyp6-like protein) - Tribolium castaneum Length = 523 Score = 119 bits (287), Expect = 2e-25 Identities = 69/229 (30%), Positives = 115/229 (50%), Gaps = 6/229 (2%) Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMF-EGHDTTAAGSSFFLSMMGIHQDIQD 381 K R +D+LL+ + +I + F G +TT++ F L + DIQD Sbjct: 290 KSRNDLIDILLQMKNDNRNFIEGDILVSQALMFFVAGFETTSSTMGFALYEFARNPDIQD 349 Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441 K+ E+ I D + + EM+YL+ C+ E LR YP VP + R+ N T+P Sbjct: 350 KIRNEIKDI-SDKYGDIKYDSLKEMEYLDMCVKEVLRKYPVVPFLDRKCNTTYTIPDTNV 408 Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501 I T + I + LH P +PN + FDP+ F +A++PF GPR+C+G + Sbjct: 409 TIDKDTPIFIPSLALHYDPQYFPNADIFDPERFSSNNKTGIDSFAYLPFGEGPRNCIGAR 468 Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQAD---IILKRAEGFQVRL 547 + +L K+ L IL+ F V+S ++S+ K++ + ++L G ++L Sbjct: 469 FGLLTAKLGLVHILKEF-VVSCNEKSNEKIKFNPKGMVLSALNGINLKL 516 >UniRef50_A7HP72 Cluster: Cytochrome P450; n=1; Parvibaculum lavamentivorans DS-1|Rep: Cytochrome P450 - Parvibaculum lavamentivorans DS-1 Length = 470 Score = 119 bits (287), Expect = 2e-25 Identities = 65/221 (29%), Positives = 120/221 (54%), Gaps = 4/221 (1%) Query: 331 LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390 L++ S++G ++ ++++++V T + GH+TTA S+ ++ +H + Q+++ EE+ + Sbjct: 251 LMVSQSKAGHEMTLDQVRDEVATFLLAGHETTATTMSWVWYLLTVHPEWQERLYEEVWAV 310 Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450 R +T D + + E LRLYPPV + R+ + L + I G T++ Sbjct: 311 --TEGRRLTIDDVPALVETRAVIEEALRLYPPVANLMRRAIKTTELTPD-ITIERGQTVL 367 Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVI 510 I+ + LHR + P++FDP FL E +A R + ++PF GPR C+G +A+L+ +I Sbjct: 368 ISPWLLHRHRFFWREPDRFDPTRFLGEEAATRPRHLYIPFGGGPRICIGASFALLEAVLI 427 Query: 511 LSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 L+T ++ RV + QA I+L+ Q + PR+ Sbjct: 428 LATFMQRARV-KVINADQVMPQARIVLRPNVALQAVVTPRR 467 Score = 53.2 bits (122), Expect = 2e-05 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%) Query: 103 DPRDVEVILSSHV-YIDKAE-EYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKS 160 DP + IL S + K + + KP LGNGLL + G WR +RKL AP F + ++ Sbjct: 74 DPDAIRRILVSDAEHFPKDDNQLAILKPLLGNGLLTAEGATWRRNRKLAAPIFQHSSVRD 133 Query: 161 FIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVS 205 F LF + + ++ F M++ T+EI+ ET + + Sbjct: 134 FAPLFVRAAERSARRALEQQGFFPLDREMTKLTLEIIGETVLSAN 178 >UniRef50_A5HG33 Cluster: Cytochrome P450 monooxygenase CYP6AE; n=2; Bombyx mori|Rep: Cytochrome P450 monooxygenase CYP6AE - Bombyx mori (Silk moth) Length = 516 Score = 119 bits (287), Expect = 2e-25 Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 3/212 (1%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 ++DE + Q + +T++ S + + Q + IEE+D F + + F Sbjct: 303 VTDELLIAQCVSFFGAAFETSSTTLSLTFYELAKNPKYQKRAIEEVDDYFAKHNNEIEFD 362 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 E YL C+ ETLRLYP + + R+V ++ T P+ G K+ GT + I Y L R P Sbjct: 363 IVSETPYLNACIDETLRLYPSLANLTREVMEDYTFPT-GLKVEKGTRIHIPVYHLQRNPK 421 Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 520 +P PNKFDP FLPE + + ++PF G R C+ ++A +++ +T+L+ + V Sbjct: 422 YFPEPNKFDPRRFLPEAKQTIYPFTYMPFGEGHRICIAMRFAKMQMLAGFATLLKKYEVA 481 Query: 521 ISDLKESDFKLQADIILKR-AEGFQVRLQPRK 551 + D + + II+ E Q++L R+ Sbjct: 482 VDDTTPQELTIDPRIIVTTPIENIQLKLIARQ 513 >UniRef50_UPI00015B60BE Cluster: PREDICTED: similar to cytochrome P450 CYP6K1; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 CYP6K1 - Nasonia vitripennis Length = 496 Score = 119 bits (286), Expect = 2e-25 Identities = 67/202 (33%), Positives = 110/202 (54%), Gaps = 10/202 (4%) Query: 323 KKRLAFLDLLLE---SSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378 +KR F+D L++ Q+ V E + Q T F G ++++ ++F L + H + Sbjct: 269 EKRGDFIDSLIQLKNGEQNPVYKFEGENLLYQSGTF-FSGFESSSTTTAFTLMELAAHPE 327 Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438 IQ++ +++++ + +T++ +MKYL++CL E +RL+PPV I R Q+ T+P Sbjct: 328 IQERARQDIERAI--EEHGMTYEAFNDMKYLDQCLAEGVRLHPPVSTIDRYTRQDYTIPG 385 Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498 I GT + I+ Y L P + P+ FDP+ F +R + AF+PF GPR CV Sbjct: 386 TDIVIEKGTAIYISLYGLQEDPRFFTRPSVFDPERFADDRKVSD---AFIPFGIGPRMCV 442 Query: 499 GRKYAMLKLKVILSTILRNFRV 520 G K L KV+L+ ILR + V Sbjct: 443 GMKAGQLHAKVVLAMILREYTV 464 >UniRef50_Q0GBX4 Cluster: Cytochrome P450 CYP3-like member 1; n=1; Ciona intestinalis|Rep: Cytochrome P450 CYP3-like member 1 - Ciona intestinalis (Transparent sea squirt) Length = 512 Score = 119 bits (286), Expect = 2e-25 Identities = 61/175 (34%), Positives = 101/175 (57%), Gaps = 5/175 (2%) Query: 346 EIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLE 405 EI ++ G+DT+A + + H+D+Q KV EE+D++ + +T++ Sbjct: 308 EITSNSVLMVLAGYDTSANALTLLAYNLATHKDVQKKVQEEIDKML-EKYGSLTYEALNS 366 Query: 406 MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPN 465 MKYL CL ETLRLYPP+ I +R N++IT+ NG +P G +++ Y + R +++ Sbjct: 367 MKYLGMCLNETLRLYPPIAINSRIPNRDITI--NGVFLPKGIQVIVPVYGMSRDEEIWEE 424 Query: 466 PNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520 P KF P+ RS + F PF GPR C+G ++A+LK+K+ ++ IL +F + Sbjct: 425 PLKFKPERMEDMRSVDP--MIFQPFGGGPRGCIGMRFAVLKIKLAVAKILHDFNL 477 Score = 34.3 bits (75), Expect = 8.6 Identities = 38/184 (20%), Positives = 70/184 (38%), Gaps = 10/184 (5%) Query: 134 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYM 189 +L++ G++W+ R + P+F LK + + ++ L K N F+ Sbjct: 124 ILMTEGEQWKRIRNTLTPSFSTAKLKEMLSIMEDCCNHAINILDKATQNDQGRFEAKSVF 183 Query: 190 SECTVEILLETAMGVSKSTQD-QSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDY 247 + ++I A V QD + G E + ++K + + + + L F F + Sbjct: 184 GKLALDITCSAAFSVDTHPQDLKDGQEPKIIKMVKQAFGFEISRSPLVM---LCFMFPAF 240 Query: 248 AKNQTKL-LDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQ 306 K KL II T + +K S + + SVE ++ G+ Sbjct: 241 EKVLCKLDYSIIPKDTVSYFANLTKSLIDQRKHSKVKPRVDLMQLMLNDQVSVEDVAKGK 300 Query: 307 SSGL 310 S GL Sbjct: 301 SKGL 304 >UniRef50_Q27664 Cluster: Cytochrome P450 6B2; n=46; Obtectomera|Rep: Cytochrome P450 6B2 - Helicoverpa armigera (Cotton bollworm) (Heliothis armigera) Length = 504 Score = 119 bits (286), Expect = 2e-25 Identities = 72/240 (30%), Positives = 123/240 (51%), Gaps = 17/240 (7%) Query: 328 FLDLLLESSQSGVAISDE--------EIKEQV---DTIMF--EGHDTTAAGSSFFLSMMG 374 F+DL+LE Q G S++ EI E V +F G++T+A ++ + Sbjct: 263 FMDLILELRQMGEITSNKYGNNMSTLEITESVMCAQAFVFYIAGYETSATTMAYLTYQLA 322 Query: 375 IHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEI 434 ++ DIQ+K+I E+D+ + VT+ +MKYL + ETLR+Y V + R+ ++ Sbjct: 323 LNPDIQNKLIAEIDEAIKANGGKVTYDTVKDMKYLNKVFDETLRMYSIVEPLQRKAIRDY 382 Query: 435 TLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGP 494 LP I T ++I+ +H P Y NP +F+P+ F E RH A++PF G Sbjct: 383 KLPGTDVVIEKDTVVLISPRGIHYDPKYYDNPKQFNPERFFAEEVGKRHPCAYLPFGLGQ 442 Query: 495 RSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD---IILKRAEGFQVRLQPRK 551 R+C+G ++ L+ + ++ +L FR + K +D LQ + I+ G ++ + PRK Sbjct: 443 RNCIGMRFGRLQSLLCITKLLSKFR-LEPSKNTDRNLQVEPYRFIIGPKGGIRLNIVPRK 501 Score = 47.6 bits (108), Expect = 9e-04 Identities = 41/136 (30%), Positives = 57/136 (41%), Gaps = 17/136 (12%) Query: 83 YDHESVVKIW--IGPRLLVFLYDPRDVEVILSSHVYIDKAEEY-----RFFKPWLGNGLL 135 + E V+ I+ P LLV RD+EVI H+ I E + F K LG L Sbjct: 66 FPEEKVIGIYRMTSPCLLV-----RDLEVI--KHIMIKDFEVFSDRGLEFSKEGLGQNLF 118 Query: 136 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSEC 192 + G WR+ R P F LK+ L N + +D + KE F+ H + Sbjct: 119 HADGDTWRTLRNRFTPIFTSGKLKNMFYLMNEGADNFIDHVSKECEKHQEFEIHTLLQTY 178 Query: 193 TVEILLETAMGVSKST 208 T+ + A GVS T Sbjct: 179 TMSTISSCAFGVSYDT 194 >UniRef50_UPI0000E48111 Cluster: PREDICTED: similar to cytochrome P450 4F6, partial; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cytochrome P450 4F6, partial - Strongylocentrotus purpuratus Length = 801 Score = 118 bits (285), Expect = 3e-25 Identities = 60/191 (31%), Positives = 112/191 (58%), Gaps = 4/191 (2%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 LD L+ + + ++D E+++++++ +F G DTT++ ++ L ++ H + Q KV EE+D Sbjct: 457 LDTLMLAKDTEGGLTDREMRDEINSFVFGGIDTTSSALTWLLYLLATHPEYQTKVQEEID 516 Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448 +F D D V +D +L +C+ E+ R+Y V R + + + + +G +PAGT Sbjct: 517 VLFQDRDPEVCSEDLHRTPFLMKCVKESQRMYSFV-TPGRLLTEPLVV--DGLTVPAGTE 573 Query: 449 LVIATYKLHRRPDVYPNPN-KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507 L + TY+LH PDV+ + + F P+ F + R +AF+PFSAG R+C+ +++A+ ++ Sbjct: 574 LTLFTYQLHHNPDVWGDDHMTFRPNRFDRQNVEGRDPFAFIPFSAGARNCIAQQFALQEI 633 Query: 508 KVILSTILRNF 518 +V I F Sbjct: 634 QVAAIRIFDKF 644 Score = 92.3 bits (219), Expect = 3e-17 Identities = 61/220 (27%), Positives = 104/220 (47%), Gaps = 15/220 (6%) Query: 92 WIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAP 151 W G + +V L P V +L+ V K+E YR F WLG + + G W+ HR+LI Sbjct: 259 WAGWKPIVVLNHPESVRNVLNGSVGTVKSEVYRLFDEWLGQPMATTDGNLWKRHRRLITN 318 Query: 152 TFHLNVLKSFIDLFNANSRAVVDKLKKE---ASNFDCHDYMSECTVEILLETAMGVSKST 208 +FH NVLKS I N + ++ + + + H S + +++L+ A Sbjct: 319 SFHFNVLKSHIPKMNQIADTLISVISQRGVAGELLELHKTTSAFSSDVILQCAFSYESGC 378 Query: 209 QDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKR 268 Q+ EY +V + I+ R L D +F+ + K+ K +D++H L +K+I Sbjct: 379 QEGVS-EYMKSVSTLAGIVMKRSLSPHLTYDFIFRRSSLYKSWRKEIDVLHRLQEKLISD 437 Query: 269 KKE--------EFASGKKPSNLNETATTSEPSTGKLTSVE 300 ++E EF+ GK ++ +T ++ + G LT E Sbjct: 438 RREQHRQTGCTEFSKGK---DILDTLMLAKDTEGGLTDRE 474 Score = 76.6 bits (180), Expect = 2e-12 Identities = 47/157 (29%), Positives = 85/157 (54%), Gaps = 5/157 (3%) Query: 363 AAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPP 422 +AG+ ++ Q+IQ I D+ FG + + +D +L +C+ E+ R+Y Sbjct: 617 SAGARNCIAQQFALQEIQVAAIRIFDK-FGFTLVRDSTEDLHRTPFLMKCVKESQRMYSF 675 Query: 423 VPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNK-FDPDNFLPERSAN 481 V R + + + + +G +PAGT L + TY+LH PDV+ + + F P F + Sbjct: 676 VSP-GRLLTEPLVV--DGLTVPAGTELTLFTYQLHHNPDVWGDDHMTFRPSRFDRQNVEG 732 Query: 482 RHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518 R +AF+PFSAG R+C+ +++A+ +++V + I F Sbjct: 733 RDPFAFIPFSAGARNCIAQQFALQEIQVAMIRIFDKF 769 >UniRef50_UPI0000E480BF Cluster: PREDICTED: similar to cytochrome P450 3A9; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cytochrome P450 3A9 - Strongylocentrotus purpuratus Length = 343 Score = 118 bits (285), Expect = 3e-25 Identities = 61/175 (34%), Positives = 96/175 (54%), Gaps = 3/175 (1%) Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404 EE+ Q + G++TT+A + ++ + D QDK+I E+D I D V++ Sbjct: 139 EELLGQAIIFLAAGYETTSALLTLTSYLLATNPDHQDKLIAEIDDIAPKRD-DVSYSTIS 197 Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464 +M YL++ + E LR+YPP + R+ + T G KI G + I Y LH P +P Sbjct: 198 KMPYLDQVVCEALRIYPPATLTDRECGETCTY--KGIKIEKGAHIWIPPYTLHHDPHHWP 255 Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519 NP KFDPD F E R+ + ++PF AGPR C+G ++A+++ K+ L L+ R Sbjct: 256 NPTKFDPDRFSKENREGRNPFTWIPFGAGPRICIGMRFALMETKMALVRSLQTVR 310 >UniRef50_UPI0000E473D8 Cluster: PREDICTED: hypothetical protein; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 507 Score = 118 bits (285), Expect = 3e-25 Identities = 58/176 (32%), Positives = 101/176 (57%), Gaps = 5/176 (2%) Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404 E + ++ T+ G +TT+ +F + +G H D+ K+ E+D++ G + ++D Sbjct: 303 ENMLDEFVTLFIAGQETTSNLLAFTILQLGRHPDVAKKLQAEVDEVLGQK-HTIQYEDLA 361 Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464 +++Y+ R L ETLRLY PV R + NG IPA T+ + +Y + R + + Sbjct: 362 KLEYMMRVLKETLRLYSPVGGTTRLTAHPVKY--NGITIPAKATVTVMSYVMSRMEEYFD 419 Query: 465 NPNKFDPDNFLPERSAN--RHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518 +P F+PD F P + RH YA+ PFS G RSC+G+++A+++ +VIL+ +L+ F Sbjct: 420 DPLLFNPDRFKPSEDGSLPRHLYAYFPFSMGQRSCIGQQFALIEARVILAKLLQRF 475 Score = 42.7 bits (96), Expect = 0.025 Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 9/149 (6%) Query: 100 FLYDPRDVEVILSSHVYIDKAEEYRFFKP-----WLGNGLLISTG-QKWRSHRKLIAPTF 153 F P V+ +L + +I E Y F+ ++G+GL+ +KW R ++ P F Sbjct: 93 FASAPEIVKELLLNSRHIKPQEIYHGFQKLYGERFMGHGLVSEVDHEKWFHRRAIMNPAF 152 Query: 154 HLNVLKSFIDLFNANSRAVVDKLKKEAS---NFDCHDYMSECTVEILLETAMGVSKSTQD 210 L S ++ +N+ S A+ KLK++A D +++ T++++ + A + + Sbjct: 153 RRKYLISLMEEYNSGSEALCQKLKEKADGKIEVPMLDELNKVTLDVIAKIAFSMDTNAIG 212 Query: 211 QSGFEYAMAVMKMCDILHLRHTKIWLRPD 239 + A+ L H + W D Sbjct: 213 DPDCPFPAAITAALQGLQSLHERPWSTMD 241 >UniRef50_A7DLL5 Cluster: Cytochrome P450; n=1; Methylobacterium extorquens PA1|Rep: Cytochrome P450 - Methylobacterium extorquens PA1 Length = 466 Score = 118 bits (285), Expect = 3e-25 Identities = 60/225 (26%), Positives = 122/225 (54%), Gaps = 6/225 (2%) Query: 328 FLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386 FL L+ + + G A+SD +++++V T + GH+TTA S+ + ++ H ++ + E Sbjct: 241 FLSALMGARDEDGTAMSDRQLRDEVITFLLAGHETTALVLSWTIHLLSRHPEVDRVLATE 300 Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446 + +I R D +++ E + E++RLYPP + R+ + + G + G Sbjct: 301 IGEIV--VQRAAAIDDVPRLRFAEHTITESMRLYPPAWAVGREARCDCQI--GGFDVRGG 356 Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506 T ++I+ + LHR P + P F P+ + + +A++PF GPR C+G ++AM++ Sbjct: 357 TPILISLWVLHRDPRFFDEPEAFRPERWHQGLAQRLPRFAYMPFGGGPRICIGNRFAMIE 416 Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 +IL+T+++ FR ++D E + + + L+ G +V ++ R+ Sbjct: 417 AVLILTTLVQRFRFVADTNEPVVPIPS-MTLRPRGGVRVIIERRE 460 Score = 44.8 bits (101), Expect = 0.006 Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 88 VVKIWIGPRLLVFLYDPRDVE-VILSSHVYIDKAEEY-RFFKPWLGNGLLISTGQKWRSH 145 VV +L++ L PR++E V++ H K E + R GNGLL S G W+ Sbjct: 54 VVAFRTAGQLMLVLTCPREIERVLVKEHQNFPKNEHFWRQVTALFGNGLLTSKGTFWQRQ 113 Query: 146 RKLIAPTFHLNVLKSFID 163 R+L AP F +L S+ D Sbjct: 114 RRLAAPAFAGPMLASYAD 131 >UniRef50_Q695H1 Cluster: Antennae-rich cytochrome P450; n=3; Polyphaga|Rep: Antennae-rich cytochrome P450 - Phyllopertha diversa (Pale-brown chafer beetle) Length = 507 Score = 118 bits (285), Expect = 3e-25 Identities = 57/192 (29%), Positives = 99/192 (51%), Gaps = 1/192 (0%) Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388 + L E G + Q G +TT++ S+ L + +++ IQ+KV+ E+ Sbjct: 277 IKLQTEGDFDGYKFEGNRVIAQAAQFFLAGFETTSSTISYALYELCLNKPIQEKVVTEIK 336 Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448 V+++ +MKYL + + E LR YP +P + R+ + +P + AGT Sbjct: 337 SAL-QQHGSVSYEAIQDMKYLHKVVQEILRKYPVLPFLDRKTTMDWKIPGTNITLEAGTP 395 Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508 + I + LH P +PNP+ FDP+ F E + +R ++++PF GPR+C+G ++ ++ K Sbjct: 396 VYIPMFGLHYDPKYFPNPDVFDPERFTEETTNSRPCFSYIPFGGGPRNCIGERFGLIGTK 455 Query: 509 VILSTILRNFRV 520 V L IL F V Sbjct: 456 VALVHILSRFEV 467 >UniRef50_A4FHE9 Cluster: Bifunctional P-450:NADPH-P450 reductase 1; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Bifunctional P-450:NADPH-P450 reductase 1 - Saccharopolyspora erythraea (strain NRRL 23338) Length = 1061 Score = 118 bits (284), Expect = 4e-25 Identities = 70/215 (32%), Positives = 110/215 (51%), Gaps = 8/215 (3%) Query: 339 GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPV 398 G + I+ Q+ T + GH+TT+ SF L + + + V E D+++GDS P Sbjct: 246 GTTLDAANIRNQIITFLIAGHETTSGTLSFALHYLAKNPTVLRLVQREADELWGDSPDPE 305 Query: 399 -TFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIP--AGTTLVIATYK 455 +F+D + Y + L ETLRL+P P RQ + L G +IP AG + Sbjct: 306 PSFEDIGRLTYTRQVLNETLRLWPSAPAFGRQARHDTVL---GGRIPMRAGEAAAVLIPM 362 Query: 456 LHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515 LHR P NP FDP F PE A R +AF PF G R+C+GR++A+ + ++L+ + Sbjct: 363 LHRSPVRGDNPELFDPARFAPEAEAARGPHAFKPFGTGERACIGRQFALDEATMVLAMLA 422 Query: 516 RNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550 +R++ D K++ + LK EG + ++ R Sbjct: 423 HRYRLV-DHAGYRLKVKETLTLK-PEGLTLAVRAR 455 >UniRef50_Q964R0 Cluster: Cytochrome P450 6k1; n=1; Blattella germanica|Rep: Cytochrome P450 6k1 - Blattella germanica (German cockroach) Length = 524 Score = 118 bits (284), Expect = 4e-25 Identities = 55/163 (33%), Positives = 86/163 (52%) Query: 358 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 417 G +T A SF L + + D+Q+++ E+ + S+ T++D M YL + ETL Sbjct: 325 GFETNATTLSFTLYELSLQPDLQNRLRSEIAGVMKTSNGKPTYEDVFGMPYLHMVVSETL 384 Query: 418 RLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPE 477 R YPP+P++ R Q+ +P I T + IA LHR P YPNP ++DP+ F E Sbjct: 385 RKYPPLPLLDRVCLQDYKVPGTDLIIERDTPVFIALLGLHRDPQYYPNPERYDPERFSEE 444 Query: 478 RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520 R Y ++PF GP +C+G ++ + +K L +L F V Sbjct: 445 NKRQRKAYTYLPFGEGPHNCIGLRFGYMAVKTALVHMLAEFEV 487 >UniRef50_UPI0000D561ED Cluster: PREDICTED: similar to Probable cytochrome P450 6a16 (CYPVIA16); n=2; Tribolium castaneum|Rep: PREDICTED: similar to Probable cytochrome P450 6a16 (CYPVIA16) - Tribolium castaneum Length = 502 Score = 118 bits (283), Expect = 5e-25 Identities = 61/198 (30%), Positives = 105/198 (53%), Gaps = 3/198 (1%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 FL +L++ +S +S +EI Q G T+A + + + QD+QDKV EE+ Sbjct: 279 FLHMLMQLRESA-GMSLKEIVSQSFLFFIAGFKTSALTMCYCIHELAHSQDLQDKVREEI 337 Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447 + G +++ + + L++ + ET+R YPP+P++ R + +P I T Sbjct: 338 HKNLGRDVSKYAYEELIALPTLDKVVKETMRKYPPLPMLNRICVKSYQVPGTDVVIDKDT 397 Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507 ++I L R P+ YP P KFDP+ F N Y ++PF GPR+C+G ++ M+K Sbjct: 398 PVIIPVLGLQRDPEFYPEPLKFDPERF--SNDNNIVPYTYLPFGDGPRNCIGLRFGMVKT 455 Query: 508 KVILSTILRNFRVISDLK 525 K+ ++ +L NFR ++ K Sbjct: 456 KLAVAALLNNFRFLASSK 473 Score = 34.7 bits (76), Expect = 6.5 Identities = 30/150 (20%), Positives = 67/150 (44%), Gaps = 8/150 (5%) Query: 79 KSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSS--HVYIDKAEEYRFFKPWLGNGLLI 136 K+ Y H + + GP + F DP V+ +L + ++D+ + L + Sbjct: 75 KAKGYKHAGIY-FFNGP--IYFPIDPDLVKRVLVTDFEYFVDRGMYGNGDELPLSCHIFS 131 Query: 137 STGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV---DKLKKEASNFDCHDYMSECT 193 G++W++ R ++P+F +KS ++ N +V L + + D D + T Sbjct: 132 MKGEEWKNIRTKMSPSFTAGKMKSIYNIVVHNCENLVKVFQPLAETRTVIDIKDILMRFT 191 Query: 194 VEILLETAMGVSKSTQDQSGFEYAMAVMKM 223 +++ T+ G+ ++ D E++ V ++ Sbjct: 192 ADVIGSTSFGIDCNSLDHPDTEFSRMVNRI 221 >UniRef50_UPI00015A5D7D Cluster: hypothetical protein LOC100037390; n=1; Danio rerio|Rep: hypothetical protein LOC100037390 - Danio rerio Length = 466 Score = 118 bits (283), Expect = 5e-25 Identities = 62/179 (34%), Positives = 102/179 (56%), Gaps = 6/179 (3%) Query: 322 QKKRLAFLDLLLESSQ--SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379 ++K +DLLL + Q S + + D+++K V+T + GHDTTA+ S+ + ++QD Sbjct: 283 KRKNTDLIDLLLLAKQKYSKIGLYDDKLKIHVNTNQYSGHDTTASALSWIFYNLAMNQDY 342 Query: 380 QDKVIEELDQIFGDSDRPV---TFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 436 Q++ E+ + D D + +D ++ + C+ E+LRL+ PV + R +Q + Sbjct: 343 QERCRAEVRDLLADRDTHTIGWSEEDLSQLTFTTMCIKESLRLHSPVLALTRYYSQNMKT 402 Query: 437 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495 P + IP G +I+ Y +HR P V+P+P FDP F P S +R +AF+PFSAGPR Sbjct: 403 PGDCV-IPHGCLCLISIYGVHRNPQVWPDPLVFDPTRFDPHNSDSRSPHAFIPFSAGPR 460 Score = 84.2 bits (199), Expect = 8e-15 Identities = 47/197 (23%), Positives = 98/197 (49%), Gaps = 8/197 (4%) Query: 92 WIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 148 ++GP +V L+ P + +L++ I + Y F KPWLGN LL+ +GQ+W HR+L Sbjct: 78 FLGPFYNMVRLFHPDYIRSLLTASASITLKDRIFYGFMKPWLGNCLLLQSGQEWSRHRRL 137 Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDK----LKKEASNFDCHDYMSECTVEILLETAMGV 204 + P FH ++LK ++ +FN ++ + D+ L + D + +S T++ LL+ Sbjct: 138 LTPAFHFDILKKYVHIFNQSTNIMHDEWRRLLASGEHSVDMFEQISSLTLDSLLKCTFSC 197 Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264 +Q++ +Y A++ + +L R + D L+ + + + ++H T Sbjct: 198 DTHSQEKPR-QYISAILDLSRLLVQRQHYLPYHWDWLYWRSAQGRRFQQACAVVHQFTAD 256 Query: 265 VIKRKKEEFASGKKPSN 281 +++ ++ + P + Sbjct: 257 IVQERRTQLDQQSDPES 273 >UniRef50_Q3EBT7 Cluster: Uncharacterized protein At2g26170.1; n=7; core eudicotyledons|Rep: Uncharacterized protein At2g26170.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 522 Score = 118 bits (283), Expect = 5e-25 Identities = 72/228 (31%), Positives = 124/228 (54%), Gaps = 13/228 (5%) Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFE----GHDTTAAGSSFFLSMMGIHQDIQDKV 383 FL L+L++ +S + + + + +E G TTA S L ++ H D++ ++ Sbjct: 294 FLSLILKARESDPFAKNIFTSDYISAVTYEHLLAGSATTAFTLSSVLYLVSGHLDVEKRL 353 Query: 384 IEELDQIFGDSDRPVTFQDTL-EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442 ++E+D FG+ D T D + YL++ + E +R Y P++AR+ +E+ + G Sbjct: 354 LQEIDG-FGNRDLIPTAHDLQHKFPYLDQVIKEAMRFYMVSPLVARETAKEVEI--GGYL 410 Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP--ERSANRHYYAFVPFSAGPRSCVGR 500 +P GT + +A L + P +P P KF P+ F P E +RH YAF+PF GPR+CVG+ Sbjct: 411 LPKGTWVWLALGVLAKDPKNFPEPEKFKPERFDPNGEEEKHRHPYAFIPFGIGPRACVGQ 470 Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQAD--IILKRAEGFQVR 546 ++A+ ++K+ L + RN+ + E + LQ D IIL G ++R Sbjct: 471 RFALQEIKLTLLHLYRNY-IFRHSLEMEIPLQLDYGIILSFKNGVKLR 517 >UniRef50_Q8T624 Cluster: Cytochrome P450 CYP9L1 protein; n=6; Cellia|Rep: Cytochrome P450 CYP9L1 protein - Anopheles gambiae (African malaria mosquito) Length = 533 Score = 118 bits (283), Expect = 5e-25 Identities = 71/216 (32%), Positives = 114/216 (52%), Gaps = 10/216 (4%) Query: 340 VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVT 399 V +S+ E+ Q G DT A +F L + + +IQ ++ EE+ Q+ D Sbjct: 316 VKLSENEMIAQCLLFFLAGFDTIATSMTFVLYEVTLAPEIQQRLYEEIQQVSETLDGKAL 375 Query: 400 FQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK-KIPAGTTLVIATYKLH 457 D L+ M+YL+ + ETLR + P P R NQ+ T+P + IP G T+ I LH Sbjct: 376 TYDALQGMRYLDMVVSETLRKWSPSPGTDRMCNQDYTIPGDPDIVIPKGATVFIPIAGLH 435 Query: 458 RRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRN 517 P YP+P++FDP+ F E A++PF GPR+C+ ++A++++K I+ IL N Sbjct: 436 YDPRFYPDPDRFDPERFNDENKHKIPLGAYLPFGIGPRNCIASRFALMEVKAIVYHILLN 495 Query: 518 FRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRM 553 + +LK S+ + + +K A+GF L+P M Sbjct: 496 Y----ELKRSE---RTSVPVKLAKGFS-PLKPENGM 523 >UniRef50_Q16FQ1 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep: Cytochrome P450 - Aedes aegypti (Yellowfever mosquito) Length = 505 Score = 118 bits (283), Expect = 5e-25 Identities = 64/221 (28%), Positives = 112/221 (50%), Gaps = 5/221 (2%) Query: 333 LESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG 392 +E+S + ++ E+ Q G +T+++ SF L + + ++Q KV E+D + Sbjct: 288 VETSTNSKKLTIGEVAAQAHVFFLAGFETSSSTMSFCLYELAKNPEVQRKVQSEIDSVTA 347 Query: 393 DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIA 452 D +T+ EM+YLE C+ ETLR YPPVP++ R+ ++ +P + I GT +++ Sbjct: 348 LHDGKLTYDSINEMRYLECCIDETLRKYPPVPVLNRECTKDYKVPDSDITIEKGTAVILQ 407 Query: 453 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 512 +H P YP+P +F P+ FL + Y PF GPR C+G + ++ KV L Sbjct: 408 ISAMHHDPQYYPDPLRFVPERFLDPDMKGKPY---APFGDGPRICIGLRMGKIQTKVGLC 464 Query: 513 TILRNFRV-ISDLKESDFKLQADIILKR-AEGFQVRLQPRK 551 +L F + KES+ + + L G +++ R+ Sbjct: 465 LLLSKFNFELYGHKESELVMSPNNFLNTPVNGINLKVSCRE 505 >UniRef50_UPI00015B62A7 Cluster: PREDICTED: similar to cytochrome P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to cytochrome P450 - Nasonia vitripennis Length = 940 Score = 117 bits (282), Expect = 7e-25 Identities = 54/175 (30%), Positives = 102/175 (58%), Gaps = 1/175 (0%) Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404 EE G++T+++ +SF L + + +IQ+K+ E+D++ S +T++ Sbjct: 724 EEAAANAFVFFLGGYETSSSTTSFCLYELAQNPEIQEKLQAEIDEVV-KSPTGLTYESIA 782 Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464 EM+YL+ L ETLR +P +PI+ R ++ LP+ I ++I+ + P+ YP Sbjct: 783 EMEYLDMVLSETLRKHPSLPILNRIAKEDYPLPTTDFVIKKDMRIMISLSGIQNNPEYYP 842 Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519 +P KFDP F E++ R+ Y +PF G R C+G+++A++++K+ L+ +L N++ Sbjct: 843 DPEKFDPLRFTKEKAVARNKYINIPFGDGERMCIGKRFAVMQVKIALAAMLHNYQ 897 >UniRef50_Q70AR8 Cluster: Putative cytochrome P450; n=1; Streptomyces peucetius|Rep: Putative cytochrome P450 - Streptomyces peucetius Length = 484 Score = 117 bits (282), Expect = 7e-25 Identities = 58/187 (31%), Positives = 105/187 (56%), Gaps = 4/187 (2%) Query: 334 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 393 + Q+G +SD++++++V T+ G++TTA + S++ H + + KV E+ ++ GD Sbjct: 265 QDEQTGERMSDKQLRDEVVTMFLGGYETTALSLVWAFSLLSRHPEAERKVRSEVAEVCGD 324 Query: 394 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIAT 453 R D ++YL E LRLYP V ++R ++ + G IPAG+ + I+ Sbjct: 325 --REPAASDLPRLRYLRAFYQEVLRLYPSVWTLSRSPLEDDEI--GGYHIPAGSQVFISP 380 Query: 454 YKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILST 513 Y +HR P + NP F P+ F + YA++PFS GPR C G A+L+ ++++ Sbjct: 381 YLMHRHPGFWENPEGFRPERFEKSATGGAPLYAYIPFSRGPRLCPGSSVAVLEAPLVIAR 440 Query: 514 ILRNFRV 520 +L+++R+ Sbjct: 441 MLQDYRL 447 >UniRef50_Q26HX2 Cluster: Cytochrome P450 hydroxylase; n=1; Flavobacteria bacterium BBFL7|Rep: Cytochrome P450 hydroxylase - Flavobacteria bacterium BBFL7 Length = 449 Score = 117 bits (282), Expect = 7e-25 Identities = 59/202 (29%), Positives = 111/202 (54%), Gaps = 7/202 (3%) Query: 329 LDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387 LD+LL S+ + G + D+++ +++ + GH+TTA SF + ++ H + +K E++ Sbjct: 235 LDMLLHSTYEDGSYMDDDQLVDEILVLFIAGHETTANALSFAVQLLAHHPETIEKAREDV 294 Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447 + D + M YL++C+ ETLRLYPP + R+ + + I G+ Sbjct: 295 SKANLDE---TLMNQLMAMPYLKQCVEETLRLYPPAYVTDREALEADEC--DDIFIEKGS 349 Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507 +++ Y++HRR D++ NP FDP F P ++ + + F PF AGPR CVG +AM+++ Sbjct: 350 IWLVSFYEMHRRKDLWENPESFDPSRFEPSKAKSYREFYF-PFGAGPRMCVGNNFAMMEM 408 Query: 508 KVILSTILRNFRVISDLKESDF 529 +++ ++ F + + D+ Sbjct: 409 MLVIRRMVERFEITTVQDHIDY 430 Score = 44.4 bits (100), Expect = 0.008 Identities = 30/121 (24%), Positives = 61/121 (50%), Gaps = 5/121 (4%) Query: 62 ALEFVGGSADIFRNIV--QKSADYDHESVVKIWIGPRLLV-FLYDPRDVEVILSSHV--Y 116 AL F+ S I+++ + + + + KI P L++ F D + + IL + Y Sbjct: 9 ALTFLAKSRQIYKDPLPFHRENFEKYGNTFKISPKPGLMIHFTCDEKITQHILQKNQKNY 68 Query: 117 IDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKL 176 + + ++G+GLL G+KWR++RKLI P F+ + +F+ + + +D++ Sbjct: 69 HKSSLQTEDLGKYIGHGLLTENGEKWRANRKLIQPAFYKKSINNFMATMDVVVKEELDRI 128 Query: 177 K 177 + Sbjct: 129 Q 129 >UniRef50_Q52S21 Cluster: Cytochrome P450; n=3; Plutella xylostella|Rep: Cytochrome P450 - Plutella xylostella (Diamondback moth) Length = 514 Score = 117 bits (282), Expect = 7e-25 Identities = 58/181 (32%), Positives = 100/181 (55%), Gaps = 2/181 (1%) Query: 340 VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVT 399 + + DE + Q G +A S++ L + +QDIQ++V+ E+D+ + D T Sbjct: 302 IEVDDELLVSQCVLFFQAGFQPSALTSAYLLYELAKNQDIQERVLAEVDEYWSTRDEVQT 361 Query: 400 FQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 459 T + +L +C+ E+LR+YPPV ++ R++ ++ TLP NG + G + I Y LH Sbjct: 362 DCVTA-LPFLAQCMEESLRMYPPVSVLMREIYKDYTLP-NGVHLKKGMMIHIPVYHLHHN 419 Query: 460 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519 P +P P F P+ F E + Y ++PF GPR C+G ++A L++ L+ +L+ +R Sbjct: 420 PKYFPEPEVFRPERFSEEGRKSIVPYTYLPFGDGPRMCIGYRFARLEIFSSLAVLLKKYR 479 Query: 520 V 520 V Sbjct: 480 V 480 >UniRef50_A0NGH0 Cluster: ENSANGP00000031109; n=7; Culicidae|Rep: ENSANGP00000031109 - Anopheles gambiae str. PEST Length = 541 Score = 117 bits (282), Expect = 7e-25 Identities = 58/216 (26%), Positives = 120/216 (55%), Gaps = 8/216 (3%) Query: 343 SDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD-RPVTFQ 401 +++E+ Q G DT + F + + ++++Q+++ EE+ +I D +P+T+ Sbjct: 324 TEKELVAQCFLFFLAGFDTVSTALGFLMYELMRNREVQERLYEEIAEIDQRLDGKPLTYD 383 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK---KIPAGTTLVIATYKLHR 458 M+Y++ + E+LRL+PP P++ R N++ T KI G T+++ LH Sbjct: 384 AVQGMRYMDMVVSESLRLWPPAPMVDRYCNRDYTFDDGEGLRFKIEKGVTVMVPVAGLHS 443 Query: 459 RPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518 P +P+P +FDP+ F E + A++PF GPR+C+G ++A++++K I+ +L++F Sbjct: 444 DPKYFPDPKRFDPERFSEENRHKINPGAYLPFGVGPRNCIGSRFALMEVKSIIYYLLKSF 503 Query: 519 RVISDLKESDFKLQ---ADIILKRAEGFQVRLQPRK 551 +++ L+ + ++L +G +R +PR+ Sbjct: 504 -TFERCEQTQVPLRLKNSPVVLAAEKGIWIRFKPRE 538 Score = 37.1 bits (82), Expect = 1.2 Identities = 16/49 (32%), Positives = 28/49 (57%) Query: 132 NGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180 N L + GQKWR R ++P F + ++ +L + + + +V+ L KEA Sbjct: 124 NSLFMLRGQKWRDMRATLSPAFTGSKMRQMFELMSDSCQGMVEHLLKEA 172 >UniRef50_UPI0000E48D2E Cluster: PREDICTED: similar to MGC64404 protein; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC64404 protein - Strongylocentrotus purpuratus Length = 509 Score = 117 bits (281), Expect = 9e-25 Identities = 55/181 (30%), Positives = 107/181 (59%), Gaps = 3/181 (1%) Query: 338 SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRP 397 +G I ++ ++ T G +TT+ +F L +G H+D+ ++ +E+D++ G S Sbjct: 300 NGEKIETADLIDEFGTFFVAGQETTSNLLAFTLLEIGRHKDVAKRLKDEVDEVLG-SKSI 358 Query: 398 VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLH 457 + D +++Y+ R ET+RL PPV +R++ ++ S G IP G +++ +Y Sbjct: 359 IEHSDLTKLEYMSRVFKETMRLNPPVSGASRELASDVQ--SCGYVIPKGASVLFLSYLTS 416 Query: 458 RRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRN 517 R + + +P F+PD F+P RH++A+ PF+ G R+C+G++ A+++ KVIL+ +L++ Sbjct: 417 RLEEYFDDPLLFNPDRFIPTDETPRHFFAYFPFAIGQRNCIGQQLALIEAKVILAKLLQS 476 Query: 518 F 518 F Sbjct: 477 F 477 Score = 35.1 bits (77), Expect = 4.9 Identities = 31/181 (17%), Positives = 74/181 (40%), Gaps = 5/181 (2%) Query: 125 FFKPWLGNGLLISTG-QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN- 182 F + +LG GL+ +KW + R L+ P F+ L +D + ++ + D L A + Sbjct: 125 FGQRFLGLGLVSQVNHEKWHTRRALLNPAFNRKYLMQMMDHKDESATRLRDHLIPLADDK 184 Query: 183 --FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDL 240 D+ + T++++ + + + + S + A+ + L D Sbjct: 185 TLVRMLDHFNNVTLDVIAKVGFDMDINAVENSDCPFPSAIALALQGMDATFKNPLLMVDP 244 Query: 241 LFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKK-PSNLNETATTSEPSTGKLTSV 299 K Y ++ + ++ + + I++++E G++ P ++ +E G + Sbjct: 245 RSKARQYRRSVRDAVKLVRNIGQDCIEKRREAKKKGEELPKDILTCILQAEDDVGNGEKI 304 Query: 300 E 300 E Sbjct: 305 E 305 >UniRef50_UPI0000E46433 Cluster: PREDICTED: similar to Cytochrome P450, family 2, subfamily u, polypeptide 1; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Cytochrome P450, family 2, subfamily u, polypeptide 1 - Strongylocentrotus purpuratus Length = 487 Score = 117 bits (281), Expect = 9e-25 Identities = 73/216 (33%), Positives = 111/216 (51%), Gaps = 10/216 (4%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 + +E+ V +M G DTT+ + + +M + DIQ KV E+D + G+ R Q Sbjct: 270 LKTKEVWRLVYDLMLAGSDTTSNTLKWAVLVMAYYPDIQKKVHNEIDCVLGE--RSPCLQ 327 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 D M Y++ +ME LR+ P +P+ + E T+ G IP G L+ + H P+ Sbjct: 328 DKKSMSYIQATIMEVLRVRPVLPLALEHLTSETTV-LRGYTIPKGAILIPNVWSCHHNPE 386 Query: 462 VYPNPNKFDPDNFLPE--RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519 + NP F+P FL E +S +AF+PFS GPR C+G + A +L +I + I++ F Sbjct: 387 YWDNPEVFNPGRFLSEDNQSLGEEPHAFLPFSFGPRKCLGDQLAKNELFLIFAKIMQRFH 446 Query: 520 V---ISDLKES-DFKLQADIILKRAEGFQVRLQPRK 551 + D ES D +IL R +VRLQPRK Sbjct: 447 IDFAPGDRPESFDEGFDKGLIL-RPNNMKVRLQPRK 481 >UniRef50_A1WAC7 Cluster: Cytochrome P450; n=1; Acidovorax sp. JS42|Rep: Cytochrome P450 - Acidovorax sp. (strain JS42) Length = 437 Score = 117 bits (281), Expect = 9e-25 Identities = 72/229 (31%), Positives = 122/229 (53%), Gaps = 9/229 (3%) Query: 328 FLDLLLESSQ--SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIE 385 +L +L+++ SG + D + ++V T++ GH+TTA+ ++ ++ H + + + Sbjct: 213 WLSMLMQARDKASGEPMPDRALLDEVMTLIVAGHETTASTLNWTWYLLARHPEAEAALHA 272 Query: 386 ELDQIFGDSDRPVTFQDT--LEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443 + P T Y+E+ L E LRLYPPV + +R+ Q+ TL G + Sbjct: 273 AIANAAPTEAAPDQALATPFASADYVEQVLQEALRLYPPVWLFSRRAVQDDTL--GGYHV 330 Query: 444 PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYA 503 PAGT + I Y LHR + P +F P F+P+ +A RH +A++PFSAGPR CVG +A Sbjct: 331 PAGTDIFICPYLLHRDAAQWERPEEFLPARFMPDAAAGRHRFAYLPFSAGPRFCVGAGFA 390 Query: 504 MLKLKVILSTILRNFR-VISDLKESDFKLQADIILKRAEGFQVRLQPRK 551 M ++ L+ + FR V D + ++ + Q I L+ ++RL R+ Sbjct: 391 MAEMATHLTMVAERFRWVPVDAEPAEAEFQ--INLRTRHPLRMRLVSRR 437 Score = 38.7 bits (86), Expect = 0.40 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 4/102 (3%) Query: 101 LYDPRDVE-VILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLK 159 ++DP D+ V+L++ K + LGNGL++S G W R++I P F + Sbjct: 51 IHDPDDIRRVLLTNRGNYVKGAGLERVRVLLGNGLIVSDGDLWVRQRRMIQPAFQGQATR 110 Query: 160 SFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILL 198 F + + ++ + A + D +S +EI+L Sbjct: 111 GFAPVVRQVNADLLTRWSAHADSGEPIDLTHELSSVALEIVL 152 >UniRef50_Q9ASR3 Cluster: At2g46960/F14M4.21; n=7; core eudicotyledons|Rep: At2g46960/F14M4.21 - Arabidopsis thaliana (Mouse-ear cress) Length = 519 Score = 117 bits (281), Expect = 9e-25 Identities = 72/211 (34%), Positives = 118/211 (55%), Gaps = 7/211 (3%) Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401 +S EEI + T F GH+TT+ ++ ++ +HQD Q+K+ EE+ + G P + + Sbjct: 310 MSIEEIIHECRTFFFGGHETTSNLLAWTTMLLSLHQDWQEKLREEIFKECGKEKTPDS-E 368 Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461 ++K + +ME+LRLY PV +AR+ + I L +IP GTT+VI K+H Sbjct: 369 TFSKLKLMNMVIMESLRLYGPVSALAREASVNIKL--GDLEIPKGTTVVIPLLKMHSDKT 426 Query: 462 VY-PNPNKFDPDNFLP--ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518 ++ + +KF+P F R+AN H A + FS GPR+C+G+ + M++ K +L+ IL+ F Sbjct: 427 LWGSDADKFNPMRFANGVSRAAN-HPNALLAFSVGPRACIGQNFVMIEAKTVLTMILQRF 485 Query: 519 RVISDLKESDFKLQADIILKRAEGFQVRLQP 549 R IS E ++ ++ G V LQP Sbjct: 486 RFISLCDEYKHTPVDNVTIQPQYGLPVMLQP 516 >UniRef50_Q013N6 Cluster: Cytochrome P450, putative; n=2; Ostreococcus|Rep: Cytochrome P450, putative - Ostreococcus tauri Length = 509 Score = 117 bits (281), Expect = 9e-25 Identities = 63/202 (31%), Positives = 116/202 (57%), Gaps = 6/202 (2%) Query: 344 DEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDT 403 +E++ ++ T + GH+T+AA + + + ++D + + E +++ G + +P Sbjct: 305 EEQMCFEIKTFLLAGHETSAAMLVWTIYELVKNEDKMTEAVAEANKVLG-AVKPGNLPTR 363 Query: 404 LEMKYLERC---LMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 460 E+ +L+ C L ETLRLY VP++ R+ ++ L G KIP GTT++I+ +H R Sbjct: 364 DELAHLDYCVSALKETLRLYSVVPVVTRRAVEDDVL--GGCKIPKGTTVIISLQGIHHRE 421 Query: 461 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520 D++PN F+P+ FL + YA++PF GPR+C+G+ A+L+ +V+L+T++R F+ Sbjct: 422 DLWPNAMSFEPERFLNGKGDEIGNYAYLPFIQGPRNCLGQYLALLEARVVLATLIRRFKF 481 Query: 521 ISDLKESDFKLQADIILKRAEG 542 S + K I + A+G Sbjct: 482 KSASANNGKKHTKAIPIAPADG 503 Score = 35.9 bits (79), Expect = 2.8 Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 90 KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL---GNGLLISTGQKWRSHR 146 ++ I R V + DP V+ ++ +++ K + ++P+L G GL+ S G+ WR+ R Sbjct: 85 RVQIFQRHCVVVADPELVKRVMQTNLKNYKKDTEFSYEPFLEILGTGLVTSEGETWRAQR 144 Query: 147 KLIAPTFHLNVLKSFI 162 + I+ + +L I Sbjct: 145 QRISSALRIEILDDII 160 >UniRef50_Q8MTC8 Cluster: Cytochrome P450 monooxygenase CYP321A1; n=1; Helicoverpa zea|Rep: Cytochrome P450 monooxygenase CYP321A1 - Heliothis zea (Corn earworm) (Bollworm) Length = 499 Score = 117 bits (281), Expect = 9e-25 Identities = 57/173 (32%), Positives = 93/173 (53%), Gaps = 3/173 (1%) Query: 358 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 417 G + A G +++ H +I KV +E+D+ F D +T+ +M+Y+++ L E+L Sbjct: 304 GVEPAADGIFATFALLSQHPEILQKVHQEIDEYFEKYDGKITYDVVCDMEYVDKVLSESL 363 Query: 418 RLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPE 477 R++PP+ + RQ + LP K+ GT L Y++H P YP+P FDP+ F E Sbjct: 364 RMFPPIGFLTRQCIHDTVLPVGNVKVAKGTKLFTPIYEIHHDPKYYPDPEVFDPERFFKE 423 Query: 478 RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFK 530 R N Y +PF G R+C+G +Y L+L + +LR+F + + ES K Sbjct: 424 RRPNDDLY--MPFGMGNRTCIGARYFKLQLLAAIVHVLRSF-TLKPIPESQQK 473 >UniRef50_A5JM35 Cluster: Cytochrome P450 Cyp6AU1; n=1; Bombyx mori|Rep: Cytochrome P450 Cyp6AU1 - Bombyx mori (Silk moth) Length = 496 Score = 117 bits (281), Expect = 9e-25 Identities = 64/217 (29%), Positives = 107/217 (49%), Gaps = 2/217 (0%) Query: 336 SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD 395 S+ V I++ + QV G+ +F L + Q IQ++++ E++ + + + Sbjct: 279 SEDFVEITEHVMAGQVFVFFAAGYVNNTITLTFSLYHLAKDQSIQERLMREIETVLENHN 338 Query: 396 RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYK 455 +T + EM YLE +ETLR++P + R ++ T+P +I GT ++I Sbjct: 339 NVLTLEAINEMSYLEMIFLETLRMHPTTNTLQRSALEDYTIPGTDIEIEKGTLVLIPPLA 398 Query: 456 LHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515 H +YP P KFDP+ F E +RH AF+ F GPR+C+G + A L+ KV + L Sbjct: 399 FHHDEKIYPEPEKFDPERFSVENHKSRHACAFLSFGIGPRTCIGIRLAKLQYKVCMVKFL 458 Query: 516 RNFRVISDLKESD-FKLQ-ADIILKRAEGFQVRLQPR 550 +RV + D +K+ L+ G V + PR Sbjct: 459 TKYRVAPSTRTKDAYKIDPLRTALEPEGGVYVDILPR 495 >UniRef50_Q59990 Cluster: Putative cytochrome P450 120; n=8; Cyanobacteria|Rep: Putative cytochrome P450 120 - Synechocystis sp. (strain PCC 6803) Length = 444 Score = 117 bits (281), Expect = 9e-25 Identities = 61/189 (32%), Positives = 107/189 (56%), Gaps = 5/189 (2%) Query: 331 LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390 LL + +S E+K+Q+ ++F GH+T + S F ++G H DI+++V +E +++ Sbjct: 228 LLAARDDNNQPLSLPELKDQILLLLFAGHETLTSALSSFCLLLGQHSDIRERVRQEQNKL 287 Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450 + +T + +M YL++ L E LRL PPV R++ Q+ G P G + Sbjct: 288 --QLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGGFRELIQDCQF--QGFHFPKGWLVS 343 Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGPRSCVGRKYAMLKLKV 509 + H PD+YP+P KFDP+ F P+ SA + +A VPF G R C+G+++A L++K+ Sbjct: 344 YQISQTHADPDLYPDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRECLGKEFARLEMKL 403 Query: 510 ILSTILRNF 518 + +++ F Sbjct: 404 FATRLIQQF 412 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.321 0.136 0.397 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 582,450,494 Number of Sequences: 1657284 Number of extensions: 23560270 Number of successful extensions: 63637 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 1558 Number of HSP's successfully gapped in prelim test: 970 Number of HSP's that attempted gapping in prelim test: 57304 Number of HSP's gapped (non-prelim): 3659 length of query: 556 length of database: 575,637,011 effective HSP length: 105 effective length of query: 451 effective length of database: 401,622,191 effective search space: 181131608141 effective search space used: 181131608141 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.9 bits) S2: 75 (34.3 bits)
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