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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001162-TA|BGIBMGA001162-PA|IPR002401|E-class P450, group
I, IPR001128|Cytochrome P450
         (556 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9VYY4 Cluster: Cytochrome P450 4g15; n=8; Neoptera|Rep...   745   0.0  
UniRef50_Q9V3S0 Cluster: Cytochrome P450 4g1; n=62; Protostomia|...   508   e-142
UniRef50_Q967Y5 Cluster: Cytochrome P450 CYP4G13v2; n=4; Neopter...   480   e-134
UniRef50_Q16ML8 Cluster: Cytochrome P450; n=3; Culicidae|Rep: Cy...   381   e-104
UniRef50_A0A8M5 Cluster: Cytochrome P450 4 family; n=1; Daphnia ...   369   e-100
UniRef50_O76478 Cluster: Corpora allata cytochrome P450; n=2; Ne...   347   3e-94
UniRef50_UPI00015B560A Cluster: PREDICTED: similar to cytochrome...   335   2e-90
UniRef50_A7SWY9 Cluster: Predicted protein; n=3; Nematostella ve...   327   5e-88
UniRef50_A0MNW4 Cluster: Cyp4M9; n=20; Obtectomera|Rep: Cyp4M9 -...   313   7e-84
UniRef50_Q964T1 Cluster: Cytochrome P450 4c21; n=1; Blattella ge...   309   1e-82
UniRef50_Q6VAB7 Cluster: Cytochrome P450 CYP4AB2; n=6; Apocrita|...   308   3e-82
UniRef50_Q27589 Cluster: Cytochrome P450 4d2; n=8; Acalyptratae|...   306   8e-82
UniRef50_UPI00015B5D09 Cluster: PREDICTED: similar to cytochrome...   300   5e-80
UniRef50_Q9Y1T8 Cluster: Cytochrome P450 4W1; n=3; Arthropoda|Re...   299   1e-79
UniRef50_UPI00015B569D Cluster: PREDICTED: similar to cytochrome...   277   4e-73
UniRef50_Q9NB96 Cluster: P450 CYP319A1; n=2; Parasitiformes|Rep:...   275   2e-72
UniRef50_UPI00015B604A Cluster: PREDICTED: similar to cytochrome...   271   3e-71
UniRef50_Q9VA27 Cluster: Cytochrome P450 4c3; n=15; Coelomata|Re...   262   1e-68
UniRef50_O45120 Cluster: Family 4 cytochrome P450; n=2; Coptoter...   253   1e-65
UniRef50_Q9VVN6 Cluster: Probable cytochrome P450 312a1; n=2; So...   242   2e-62
UniRef50_UPI00015B5014 Cluster: PREDICTED: similar to cytochrome...   239   1e-61
UniRef50_UPI0000D566B3 Cluster: PREDICTED: similar to Cytochrome...   237   6e-61
UniRef50_Q6ZWL3 Cluster: Cytochrome P450 4V2; n=83; Coelomata|Re...   226   1e-57
UniRef50_UPI0000E46807 Cluster: PREDICTED: similar to cytochrome...   226   1e-57
UniRef50_UPI00015B561A Cluster: PREDICTED: similar to cytochrome...   225   2e-57
UniRef50_A0JMQ6 Cluster: Cytochrome P450, family 4, subfamily V,...   221   3e-56
UniRef50_Q9NGQ5 Cluster: Insecticide resistance-associated cytoc...   219   2e-55
UniRef50_A1BPS2 Cluster: CYP4BF1; n=2; Ips paraconfusus|Rep: CYP...   213   1e-53
UniRef50_Q178T9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...   210   7e-53
UniRef50_Q695H3 Cluster: Pheromone-degrading enzyme; n=2; Phyllo...   210   1e-52
UniRef50_UPI0000D55ACE Cluster: PREDICTED: similar to Cytochrome...   209   2e-52
UniRef50_Q170T4 Cluster: Cytochrome P450; n=5; Endopterygota|Rep...   209   2e-52
UniRef50_Q8ISJ8 Cluster: Cytochrome P450 CYP4S4; n=3; Noctuidae|...   208   2e-52
UniRef50_O17851 Cluster: Putative uncharacterized protein cyp-37...   208   3e-52
UniRef50_UPI0000D55B03 Cluster: PREDICTED: similar to Cytochrome...   206   1e-51
UniRef50_UPI0000D55952 Cluster: PREDICTED: similar to Cytochrome...   205   3e-51
UniRef50_Q27472 Cluster: Cytochrome p450 family protein 32A1; n=...   204   6e-51
UniRef50_Q9U1R5 Cluster: Putative uncharacterized protein cyp-42...   203   8e-51
UniRef50_UPI0000D56462 Cluster: PREDICTED: similar to cytochrome...   202   2e-50
UniRef50_UPI0000D56049 Cluster: PREDICTED: similar to Probable c...   201   4e-50
UniRef50_Q7YXL0 Cluster: Cytochrome P450 monooxygenase; n=2; Tri...   200   6e-50
UniRef50_UPI00015B569E Cluster: PREDICTED: similar to cytochrome...   198   3e-49
UniRef50_Q179B7 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   198   3e-49
UniRef50_Q16IS6 Cluster: Cytochrome P450; n=12; Culicidae|Rep: C...   196   2e-48
UniRef50_UPI0000E46144 Cluster: PREDICTED: similar to ENSANGP000...   195   3e-48
UniRef50_Q9N574 Cluster: Cytochrome p450 family protein 31A3; n=...   195   3e-48
UniRef50_Q9N4Q5 Cluster: Cytochrome p450 family protein 32B1; n=...   194   5e-48
UniRef50_Q7YSZ3 Cluster: P450 enzyme precursor; n=1; Rhodnius pr...   192   3e-47
UniRef50_UPI0000D5646A Cluster: PREDICTED: similar to CYtochrome...   191   4e-47
UniRef50_Q9VS79 Cluster: Cytochrome P450 4d8; n=6; Schizophora|R...   190   6e-47
UniRef50_Q170T0 Cluster: Cytochrome P450; n=12; Culicidae|Rep: C...   190   1e-46
UniRef50_Q9V7G5 Cluster: Probable cytochrome P450 4aa1; n=5; Dip...   190   1e-46
UniRef50_Q8ISJ7 Cluster: Cytochrome P450 CYP4L4; n=4; Noctuidae|...   189   2e-46
UniRef50_A1BPS3 Cluster: CYP4BG1; n=1; Ips paraconfusus|Rep: CYP...   188   3e-46
UniRef50_Q16I47 Cluster: Cytochrome P450; n=7; Culicidae|Rep: Cy...   188   4e-46
UniRef50_Q9VMS9 Cluster: Probable cytochrome P450 4ac1; n=5; Sop...   187   8e-46
UniRef50_P33269 Cluster: Cytochrome P450 4d1; n=11; Diptera|Rep:...   186   1e-45
UniRef50_Q9XVA6 Cluster: Putative uncharacterized protein cyp-37...   186   1e-45
UniRef50_Q4R1I7 Cluster: Cytochrome P450; n=1; Papilio xuthus|Re...   186   1e-45
UniRef50_A1BPR9 Cluster: CYP4BD1; n=1; Ips paraconfusus|Rep: CYP...   186   2e-45
UniRef50_Q9VXY0 Cluster: Probable cytochrome P450 4s3; n=5; Acal...   186   2e-45
UniRef50_UPI0000D9991B Cluster: PREDICTED: similar to cytochrome...   184   5e-45
UniRef50_A1BPS5 Cluster: CYP4BJ1; n=1; Ips paraconfusus|Rep: CYP...   184   5e-45
UniRef50_A6Y7S1 Cluster: Female neotenic-specific protein 4; n=1...   184   7e-45
UniRef50_A1BPS4 Cluster: CYP4BH1; n=1; Ips paraconfusus|Rep: CYP...   183   1e-44
UniRef50_Q16TD6 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...   183   1e-44
UniRef50_P13584 Cluster: Cytochrome P450 4B1; n=32; Euteleostomi...   182   2e-44
UniRef50_UPI00015B61D7 Cluster: PREDICTED: similar to Cytochrome...   180   7e-44
UniRef50_Q02928 Cluster: Cytochrome P450 4A11 precursor; n=114; ...   180   1e-43
UniRef50_UPI00015B5E04 Cluster: PREDICTED: similar to CG8302-PA;...   178   4e-43
UniRef50_Q9N525 Cluster: Cytochrome p450 family protein 29A3; n=...   177   5e-43
UniRef50_UPI00015B4DC8 Cluster: PREDICTED: similar to corpora al...   177   6e-43
UniRef50_UPI0000D56470 Cluster: PREDICTED: similar to Cytochrome...   177   6e-43
UniRef50_UPI0000F2BA18 Cluster: PREDICTED: similar to Cytochrome...   177   8e-43
UniRef50_UPI00015B5196 Cluster: PREDICTED: similar to cytochrome...   176   1e-42
UniRef50_Q4U3Y4 Cluster: CYP325C2; n=4; Anopheles gambiae|Rep: C...   175   3e-42
UniRef50_Q6PW73 Cluster: Cytochrome P450 CYP4AT1; n=1; Capitella...   175   3e-42
UniRef50_Q8K4D6 Cluster: Cytochrome P450 4X1; n=15; Eutheria|Rep...   172   2e-41
UniRef50_Q17DZ0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   171   3e-41
UniRef50_Q27606 Cluster: Cytochrome P450 4e2; n=11; Diptera|Rep:...   170   1e-40
UniRef50_Q16L55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   169   1e-40
UniRef50_Q170T3 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   169   2e-40
UniRef50_Q6NT55 Cluster: Cytochrome P450 4F22; n=127; Deuterosto...   168   4e-40
UniRef50_Q9V558 Cluster: Cytochrome P450 4p1; n=5; Sophophora|Re...   167   5e-40
UniRef50_Q6TGT4 Cluster: Thromboxane A synthase 1; n=6; cellular...   167   9e-40
UniRef50_Q16P39 Cluster: Cytochrome P450; n=7; Aedes aegypti|Rep...   166   1e-39
UniRef50_Q8N118 Cluster: Cytochrome P450 4X1; n=12; Mammalia|Rep...   166   2e-39
UniRef50_A1BPR7 Cluster: CYP4AY1; n=2; Ips paraconfusus|Rep: CYP...   165   2e-39
UniRef50_Q170S9 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cy...   165   4e-39
UniRef50_UPI00015B5723 Cluster: PREDICTED: similar to cytochrome...   164   6e-39
UniRef50_Q17PE3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep...   164   6e-39
UniRef50_O46054 Cluster: Cytochrome P450 4ae1; n=1; Drosophila m...   164   6e-39
UniRef50_Q9VLZ7 Cluster: Probable cytochrome P450 4d21; n=5; Sop...   163   8e-39
UniRef50_Q4STK8 Cluster: Chromosome undetermined SCAF14158, whol...   163   1e-38
UniRef50_Q177R7 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep...   162   3e-38
UniRef50_UPI0001555B83 Cluster: PREDICTED: similar to cytochrome...   161   3e-38
UniRef50_Q16L50 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   161   4e-38
UniRef50_Q6SPQ6 Cluster: CYP4BB1; n=2; Protostomia|Rep: CYP4BB1 ...   161   6e-38
UniRef50_Q17PE0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   160   1e-37
UniRef50_Q7QCC3 Cluster: ENSANGP00000012179; n=1; Anopheles gamb...   156   1e-36
UniRef50_UPI0000D56467 Cluster: PREDICTED: similar to Cytochrome...   156   2e-36
UniRef50_Q16E69 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   156   2e-36
UniRef50_UPI0000D56469 Cluster: PREDICTED: similar to cytochrome...   155   2e-36
UniRef50_Q176V3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep...   155   2e-36
UniRef50_Q178V0 Cluster: Cytochrome P450; n=2; Culicidae|Rep: Cy...   155   4e-36
UniRef50_UPI0000D5558E Cluster: PREDICTED: similar to Cytochrome...   151   4e-35
UniRef50_Q9VGB4 Cluster: Probable cytochrome P450 313a2; n=2; Dr...   150   8e-35
UniRef50_Q5XM61 Cluster: Cytochrome P450; n=9; Pancrustacea|Rep:...   149   1e-34
UniRef50_Q6PH32 Cluster: Cytochrome P450, family 4; n=7; Clupeoc...   149   2e-34
UniRef50_Q8WQN5 Cluster: Cytochrome P450 CYP4H14; n=22; Endopter...   149   2e-34
UniRef50_Q095M8 Cluster: Cytochrome P450 4A5; n=1; Stigmatella a...   148   4e-34
UniRef50_Q5V5P9 Cluster: Cytochrome P450; n=3; Halobacteriaceae|...   148   4e-34
UniRef50_A6GGL1 Cluster: Cytochrome P450 family protein; n=1; Pl...   147   8e-34
UniRef50_Q9VG40 Cluster: Probable cytochrome P450 313a4; n=3; So...   147   8e-34
UniRef50_UPI00005A2E9B Cluster: PREDICTED: similar to cytochrome...   146   1e-33
UniRef50_UPI0000F21E21 Cluster: PREDICTED: similar to cytochrome...   146   2e-33
UniRef50_UPI0000D55FA3 Cluster: PREDICTED: similar to Cytochrome...   145   3e-33
UniRef50_A7RNE6 Cluster: Predicted protein; n=1; Nematostella ve...   145   3e-33
UniRef50_A7SJV6 Cluster: Predicted protein; n=3; Nematostella ve...   144   4e-33
UniRef50_UPI0000D56428 Cluster: PREDICTED: similar to Cytochrome...   144   5e-33
UniRef50_Q6SPQ5 Cluster: CYP342A1; n=1; Nereis virens|Rep: CYP34...   144   5e-33
UniRef50_UPI0000E4657A Cluster: PREDICTED: similar to cytochrome...   144   7e-33
UniRef50_Q06GC7 Cluster: Cytochrome P450; n=1; Rhodococcus sp. N...   142   2e-32
UniRef50_Q16L53 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...   142   3e-32
UniRef50_Q179B9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...   141   4e-32
UniRef50_A7SXR0 Cluster: Predicted protein; n=5; Nematostella ve...   141   4e-32
UniRef50_Q8UF31 Cluster: Cytochrome P450; n=1; Agrobacterium tum...   140   7e-32
UniRef50_Q8T632 Cluster: Cytochrome P450 CYP6P3; n=42; Diptera|R...   140   7e-32
UniRef50_Q86GR1 Cluster: Cytochrome P450 CYPm3r5; n=12; Culicida...   140   7e-32
UniRef50_Q89R90 Cluster: Blr2882 protein; n=4; Bacteria|Rep: Blr...   140   9e-32
UniRef50_A7D7T8 Cluster: Cytochrome P450; n=1; Halorubrum lacusp...   140   1e-31
UniRef50_UPI00015B4AC4 Cluster: PREDICTED: similar to cytochrome...   139   2e-31
UniRef50_Q82D73 Cluster: Putative cytochrome P450; n=2; Streptom...   139   2e-31
UniRef50_Q4U3Y5 Cluster: CYP325D1; n=1; Anopheles gambiae|Rep: C...   139   2e-31
UniRef50_Q5U3Q3 Cluster: Cytochrome P450, family 3, subfamily c,...   139   2e-31
UniRef50_Q9BID0 Cluster: Cytochrome P450; n=27; Culicidae|Rep: C...   139   2e-31
UniRef50_Q7QH22 Cluster: ENSANGP00000012679; n=5; Cellia|Rep: EN...   138   3e-31
UniRef50_P05184 Cluster: Cytochrome P450 3A3; n=159; Euteleostom...   138   3e-31
UniRef50_Q8WQN1 Cluster: Cytochrome P450 CYP4H24; n=23; Culicida...   138   4e-31
UniRef50_Q0IG08 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   138   4e-31
UniRef50_O76107 Cluster: Cytochrome P450; n=2; Culicini|Rep: Cyt...   138   4e-31
UniRef50_UPI00015B5073 Cluster: PREDICTED: similar to cytochrome...   137   6e-31
UniRef50_UPI0000D56468 Cluster: PREDICTED: similar to Cytochrome...   137   6e-31
UniRef50_UPI0000D555E9 Cluster: PREDICTED: similar to Cytochrome...   137   6e-31
UniRef50_A5P357 Cluster: Cytochrome P450; n=1; Methylobacterium ...   137   6e-31
UniRef50_Q3E385 Cluster: Cytochrome P450; n=3; Chloroflexus|Rep:...   137   8e-31
UniRef50_Q9V4T3 Cluster: Probable cytochrome P450 4ad1; n=2; Sop...   137   8e-31
UniRef50_Q3I414 Cluster: Cytochrome P450; n=18; Cucujiformia|Rep...   136   1e-30
UniRef50_UPI0000D576F7 Cluster: PREDICTED: similar to Cytochrome...   136   2e-30
UniRef50_Q0LLJ2 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   136   2e-30
UniRef50_UPI00015B5352 Cluster: PREDICTED: similar to cytochrome...   135   3e-30
UniRef50_Q98T91 Cluster: Cytochrome P450 3A40; n=16; Euteleostom...   135   3e-30
UniRef50_Q9PWP0 Cluster: Cytochrome P450; n=2; Dicentrarchus lab...   135   3e-30
UniRef50_Q8WQN9 Cluster: Cytochrome P450 CYP4J5; n=22; Endoptery...   134   4e-30
UniRef50_UPI0000E4963D Cluster: PREDICTED: similar to cytochrome...   134   6e-30
UniRef50_UPI0000E48EAF Cluster: PREDICTED: similar to cytochrome...   134   6e-30
UniRef50_UPI000065CBAF Cluster: Thromboxane-A synthase (EC 5.3.9...   134   8e-30
UniRef50_Q1D9Z9 Cluster: Cytochrome P450 family protein; n=1; My...   134   8e-30
UniRef50_Q5TXA2 Cluster: ENSANGP00000026709; n=2; Anopheles gamb...   134   8e-30
UniRef50_Q495Y1 Cluster: CYP3A43 protein; n=4; Homo sapiens|Rep:...   134   8e-30
UniRef50_Q0IEL1 Cluster: Cytochrome P450; n=6; Culicini|Rep: Cyt...   133   1e-29
UniRef50_A7DM29 Cluster: Cytochrome P450; n=2; Methylobacterium ...   133   1e-29
UniRef50_Q9PVE8 Cluster: Cytochrome P450 3A30; n=4; Percomorpha|...   133   1e-29
UniRef50_O76345 Cluster: Cytochrome P450; n=1; Homarus americanu...   132   2e-29
UniRef50_Q70AR5 Cluster: Putative cytochrome P450; n=1; Streptom...   132   2e-29
UniRef50_Q9VGB5 Cluster: Probable cytochrome P450 313a5; n=2; Dr...   132   2e-29
UniRef50_Q309A5 Cluster: Cytochrome P450 monooxygenase; n=22; Ap...   132   3e-29
UniRef50_P33270 Cluster: Cytochrome P450 6a2; n=10; Diptera|Rep:...   132   3e-29
UniRef50_Q9VYQ7 Cluster: Probable cytochrome P450 311a1; n=2; Dr...   132   3e-29
UniRef50_UPI00015B480C Cluster: PREDICTED: similar to cytochrome...   131   4e-29
UniRef50_A7RQ80 Cluster: Predicted protein; n=5; Nematostella ve...   131   4e-29
UniRef50_O16156 Cluster: Cytochrome P450 30; n=1; Mercenaria mer...   131   5e-29
UniRef50_A1UDQ6 Cluster: Cytochrome P450; n=10; Mycobacterium|Re...   130   1e-28
UniRef50_A7RSL1 Cluster: Predicted protein; n=2; Nematostella ve...   130   1e-28
UniRef50_A3RK60 Cluster: Cytochrome P450; n=2; Liposcelis bostry...   130   1e-28
UniRef50_UPI0000D56564 Cluster: PREDICTED: similar to Probable c...   129   2e-28
UniRef50_Q29AT3 Cluster: GA11819-PA; n=6; Diptera|Rep: GA11819-P...   129   2e-28
UniRef50_Q964R1 Cluster: Cytochrome P450 6j1; n=1; Blattella ger...   129   2e-28
UniRef50_UPI00015B60B4 Cluster: PREDICTED: similar to cytochrome...   128   3e-28
UniRef50_Q0LK65 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   128   3e-28
UniRef50_Q9KFA6 Cluster: Cytochrome P450 hydroxylase; n=1; Bacil...   128   4e-28
UniRef50_Q9VGB3 Cluster: Probable cytochrome P450 313a3; n=2; Dr...   128   4e-28
UniRef50_UPI00015B595F Cluster: PREDICTED: similar to cytochrome...   128   5e-28
UniRef50_Q629N7 Cluster: Cytochrome P450-related protein; n=24; ...   128   5e-28
UniRef50_Q5W1K8 Cluster: Cytochrome P450 CYP6AX1 protein; n=2; H...   127   7e-28
UniRef50_UPI0000D56E82 Cluster: PREDICTED: similar to Cytochrome...   127   9e-28
UniRef50_A0NQ01 Cluster: Cytochrome P450; n=1; Stappia aggregata...   127   9e-28
UniRef50_Q6PW74 Cluster: Cytochrome P450 CYP331A1; n=1; Capitell...   127   9e-28
UniRef50_Q8WQM9 Cluster: Cytochrome P450 CYP6M1; n=7; Culicidae|...   126   1e-27
UniRef50_Q162V4 Cluster: Cytochrome P450 family protein, putativ...   126   2e-27
UniRef50_Q3IR83 Cluster: Unspecific monooxygenase; n=1; Natronom...   126   2e-27
UniRef50_UPI0000DB7C31 Cluster: PREDICTED: similar to Probable c...   126   2e-27
UniRef50_Q70AR1 Cluster: Putative cytochrome P450; n=1; Streptom...   126   2e-27
UniRef50_Q3L917 Cluster: Cytochrome P450; n=1; Rhodococcus eryth...   126   2e-27
UniRef50_Q5KR92 Cluster: Cytochrome P450; n=1; Hodotermopsis sjo...   125   3e-27
UniRef50_A7SCY4 Cluster: Predicted protein; n=1; Nematostella ve...   125   3e-27
UniRef50_Q27594 Cluster: Cytochrome P450 6a9; n=15; Schizophora|...   125   3e-27
UniRef50_A3RIC1 Cluster: Cytochrome P450; n=1; Bombyx mori|Rep: ...   125   4e-27
UniRef50_Q8MZK0 Cluster: Cytochrome P450; n=6; Culicidae|Rep: Cy...   124   5e-27
UniRef50_UPI0000D576F6 Cluster: PREDICTED: similar to Probable c...   124   8e-27
UniRef50_Q9V4U7 Cluster: Probable cytochrome P450 6a14; n=10; Sc...   124   8e-27
UniRef50_Q1IM54 Cluster: Cytochrome P450; n=1; Acidobacteria bac...   123   1e-26
UniRef50_A7LFI0 Cluster: Cytochrome P450; n=3; Tribolium castane...   123   1e-26
UniRef50_Q0LL77 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   123   1e-26
UniRef50_A7SRX7 Cluster: Predicted protein; n=2; Nematostella ve...   123   1e-26
UniRef50_Q964T2 Cluster: Cytochrome P450 9e2; n=2; Blattaria|Rep...   122   2e-26
UniRef50_Q9V769 Cluster: Cytochrome P450 6a22; n=2; Sophophora|R...   122   2e-26
UniRef50_Q825N1 Cluster: Cytochrome P450 hydroxylase; n=6; Actin...   122   3e-26
UniRef50_Q0LFI0 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   122   3e-26
UniRef50_A7T1A2 Cluster: Predicted protein; n=2; Nematostella ve...   122   3e-26
UniRef50_Q9GQM9 Cluster: Cytochrome P450 6l1; n=1; Blattella ger...   122   3e-26
UniRef50_UPI0000D5650B Cluster: PREDICTED: similar to Cytochrome...   122   3e-26
UniRef50_UPI00015B4FBC Cluster: PREDICTED: similar to cytochrome...   121   4e-26
UniRef50_Q0LJ67 Cluster: Cytochrome P450; n=2; cellular organism...   121   4e-26
UniRef50_Q27691 Cluster: Cytochrome P450; n=2; Musca domestica|R...   121   4e-26
UniRef50_P29980 Cluster: Probable cytochrome P450 110; n=2; Nost...   121   4e-26
UniRef50_Q16F55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   121   6e-26
UniRef50_Q069I9 Cluster: Gossypol-induced cytochrome P450; n=9; ...   120   8e-26
UniRef50_UPI0000DB6FEA Cluster: PREDICTED: similar to Probable c...   120   1e-25
UniRef50_UPI0000D577ED Cluster: PREDICTED: similar to Cytochrome...   119   2e-25
UniRef50_A7HP72 Cluster: Cytochrome P450; n=1; Parvibaculum lava...   119   2e-25
UniRef50_A5HG33 Cluster: Cytochrome P450 monooxygenase CYP6AE; n...   119   2e-25
UniRef50_UPI00015B60BE Cluster: PREDICTED: similar to cytochrome...   119   2e-25
UniRef50_Q0GBX4 Cluster: Cytochrome P450 CYP3-like member 1; n=1...   119   2e-25
UniRef50_Q27664 Cluster: Cytochrome P450 6B2; n=46; Obtectomera|...   119   2e-25
UniRef50_UPI0000E48111 Cluster: PREDICTED: similar to cytochrome...   118   3e-25
UniRef50_UPI0000E480BF Cluster: PREDICTED: similar to cytochrome...   118   3e-25
UniRef50_UPI0000E473D8 Cluster: PREDICTED: hypothetical protein;...   118   3e-25
UniRef50_A7DLL5 Cluster: Cytochrome P450; n=1; Methylobacterium ...   118   3e-25
UniRef50_Q695H1 Cluster: Antennae-rich cytochrome P450; n=3; Pol...   118   3e-25
UniRef50_A4FHE9 Cluster: Bifunctional P-450:NADPH-P450 reductase...   118   4e-25
UniRef50_Q964R0 Cluster: Cytochrome P450 6k1; n=1; Blattella ger...   118   4e-25
UniRef50_UPI0000D561ED Cluster: PREDICTED: similar to Probable c...   118   5e-25
UniRef50_UPI00015A5D7D Cluster: hypothetical protein LOC10003739...   118   5e-25
UniRef50_Q3EBT7 Cluster: Uncharacterized protein At2g26170.1; n=...   118   5e-25
UniRef50_Q8T624 Cluster: Cytochrome P450 CYP9L1 protein; n=6; Ce...   118   5e-25
UniRef50_Q16FQ1 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep...   118   5e-25
UniRef50_UPI00015B62A7 Cluster: PREDICTED: similar to cytochrome...   117   7e-25
UniRef50_Q70AR8 Cluster: Putative cytochrome P450; n=1; Streptom...   117   7e-25
UniRef50_Q26HX2 Cluster: Cytochrome P450 hydroxylase; n=1; Flavo...   117   7e-25
UniRef50_Q52S21 Cluster: Cytochrome P450; n=3; Plutella xylostel...   117   7e-25
UniRef50_A0NGH0 Cluster: ENSANGP00000031109; n=7; Culicidae|Rep:...   117   7e-25
UniRef50_UPI0000E48D2E Cluster: PREDICTED: similar to MGC64404 p...   117   9e-25
UniRef50_UPI0000E46433 Cluster: PREDICTED: similar to Cytochrome...   117   9e-25
UniRef50_A1WAC7 Cluster: Cytochrome P450; n=1; Acidovorax sp. JS...   117   9e-25
UniRef50_Q9ASR3 Cluster: At2g46960/F14M4.21; n=7; core eudicotyl...   117   9e-25
UniRef50_Q013N6 Cluster: Cytochrome P450, putative; n=2; Ostreoc...   117   9e-25
UniRef50_Q8MTC8 Cluster: Cytochrome P450 monooxygenase CYP321A1;...   117   9e-25
UniRef50_A5JM35 Cluster: Cytochrome P450 Cyp6AU1; n=1; Bombyx mo...   117   9e-25
UniRef50_Q59990 Cluster: Putative cytochrome P450 120; n=8; Cyan...   117   9e-25
UniRef50_UPI000038CC01 Cluster: COG2124: Cytochrome P450; n=1; N...   116   1e-24
UniRef50_Q8YMU4 Cluster: Cytochrome P450; n=10; Cyanobacteria|Re...   116   1e-24
UniRef50_A6FMY4 Cluster: Cytochrome P450; n=12; Rhodobacterales|...   116   1e-24
UniRef50_Q31NH2 Cluster: Cytochrome P450; n=2; Synechococcus elo...   116   2e-24
UniRef50_Q17BD6 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   116   2e-24
UniRef50_UPI0000D561F4 Cluster: PREDICTED: similar to Cytochrome...   116   2e-24
UniRef50_Q89VZ9 Cluster: Bll0894 protein; n=13; Alphaproteobacte...   116   2e-24
UniRef50_Q82IV2 Cluster: Cytochrome P450 hydroxylase; n=2; Strep...   116   2e-24
UniRef50_A5FJE6 Cluster: Cytochrome P450; n=1; Flavobacterium jo...   116   2e-24
UniRef50_A7PQ75 Cluster: Chromosome chr18 scaffold_24, whole gen...   116   2e-24
UniRef50_Q5XNT3 Cluster: Cytochrome P450; n=2; Anopheles gambiae...   116   2e-24
UniRef50_Q5TCH5 Cluster: Cytochrome P450, family 4, subfamily A,...   116   2e-24
UniRef50_UPI00015B6167 Cluster: PREDICTED: similar to cytochrome...   115   3e-24
UniRef50_Q7SY18 Cluster: Zgc:63602; n=2; Danio rerio|Rep: Zgc:63...   115   3e-24
UniRef50_Q82IY3 Cluster: Pentalenene C13 hydroxylase; cytochrome...   115   3e-24
UniRef50_Q8KUI0 Cluster: Cytochrome P450; n=1; Actinosynnema pre...   115   3e-24
UniRef50_Q2Y711 Cluster: Cytochrome P450; n=1; Nitrosospira mult...   115   4e-24
UniRef50_A3VL14 Cluster: Possible cytochrome P450 hydroxylase su...   115   4e-24
UniRef50_A7RMN2 Cluster: Predicted protein; n=1; Nematostella ve...   115   4e-24
UniRef50_Q9VG82 Cluster: Probable cytochrome P450 9f2; n=26; End...   115   4e-24
UniRef50_Q603T8 Cluster: Cytochrome P450 51; n=1; Methylococcus ...   114   5e-24
UniRef50_A1ZWE3 Cluster: Cytochrome P450 family protein; n=1; Mi...   114   5e-24
UniRef50_A7SWV9 Cluster: Predicted protein; n=1; Nematostella ve...   114   5e-24
UniRef50_UPI00015B5C73 Cluster: PREDICTED: similar to cytochrome...   114   7e-24
UniRef50_UPI00003BFC2E Cluster: PREDICTED: similar to Probable c...   114   7e-24
UniRef50_Q6DHE1 Cluster: Zgc:109896 protein; n=20; Euteleostomi|...   114   7e-24
UniRef50_A4D937 Cluster: CrpE; n=1; Nostoc sp. ATCC 53789|Rep: C...   114   7e-24
UniRef50_A1ZZK3 Cluster: Cytochrome P450 4A10; n=1; Microscilla ...   114   7e-24
UniRef50_UPI000038DD76 Cluster: COG2124: Cytochrome P450; n=1; N...   113   9e-24
UniRef50_P13527 Cluster: Cytochrome P450 6A1; n=3; Musca domesti...   113   9e-24
UniRef50_UPI0000DB6D9C Cluster: PREDICTED: similar to Cytochrome...   113   1e-23
UniRef50_Q5W1K7 Cluster: Cytochrome P450 CYP6AY1 protein; n=3; H...   113   1e-23
UniRef50_UPI0000E49A50 Cluster: PREDICTED: hypothetical protein;...   113   2e-23
UniRef50_A1HDJ4 Cluster: Cytochrome P450; n=4; Burkholderiaceae|...   113   2e-23
UniRef50_Q82QD5 Cluster: Putative cytochrome P450 / NADPH-ferrih...   112   2e-23
UniRef50_UPI0000E473EA Cluster: PREDICTED: hypothetical protein;...   112   3e-23
UniRef50_UPI0000D56CEB Cluster: PREDICTED: similar to Probable c...   112   3e-23
UniRef50_A3Q0Q7 Cluster: Cytochrome P450 precursor; n=3; Mycobac...   112   3e-23
UniRef50_Q0NZP1 Cluster: Ent-kaurenoic acid 13-hydroxylase; n=2;...   112   3e-23
UniRef50_O48925 Cluster: CYP82C1p; n=5; core eudicotyledons|Rep:...   112   3e-23
UniRef50_Q9NB69 Cluster: Cytochrome P450 monooxygenase; n=2; Tri...   112   3e-23
UniRef50_UPI0000E49F6F Cluster: PREDICTED: similar to cytochrome...   111   4e-23
UniRef50_Q8YN84 Cluster: Cytochrome P450; n=4; cellular organism...   111   4e-23
UniRef50_Q1DEH2 Cluster: Cytochrome P450 family protein; n=1; My...   111   4e-23
UniRef50_A6G0E4 Cluster: Cytochrome P450 51; n=1; Plesiocystis p...   111   4e-23
UniRef50_A0YL42 Cluster: Cytochrome P450; n=2; Cyanobacteria|Rep...   111   4e-23
UniRef50_A5YU13 Cluster: CYP97C3; n=1; Chlamydomonas reinhardtii...   111   4e-23
UniRef50_Q4SQM7 Cluster: Chromosome 17 SCAF14532, whole genome s...   111   5e-23
UniRef50_Q56JT9 Cluster: Cytochrome P450 monooxygenase; n=10; En...   111   5e-23
UniRef50_Q3I415 Cluster: Cytochrome P450; n=1; Leptinotarsa dece...   111   5e-23
UniRef50_Q25176 Cluster: Cytochrome P-450; n=24; Ditrysia|Rep: C...   111   5e-23
UniRef50_A6S200 Cluster: Putative uncharacterized protein; n=1; ...   111   5e-23
UniRef50_Q9V9L1 Cluster: Probable cytochrome P450 6w1; n=3; Dros...   111   6e-23
UniRef50_UPI00015B5FEA Cluster: PREDICTED: similar to cytochrome...   110   8e-23
UniRef50_Q3E1G3 Cluster: Cytochrome P450; n=2; Chloroflexus|Rep:...   110   8e-23
UniRef50_A6G220 Cluster: Cytochrome P450; n=1; Plesiocystis paci...   110   8e-23
UniRef50_A4X8D8 Cluster: Cytochrome P450; n=5; Actinomycetales|R...   110   8e-23
UniRef50_A0YW07 Cluster: Cytochrome P450 hydroxylase; n=1; Lyngb...   110   8e-23
UniRef50_Q8T5C1 Cluster: Cytochrome P450 monooxygenase CYP6X1v1;...   110   8e-23
UniRef50_A7SF10 Cluster: Predicted protein; n=1; Nematostella ve...   110   8e-23
UniRef50_A6SDR2 Cluster: Cytochrome P450 52; n=2; Sclerotiniacea...   110   8e-23
UniRef50_UPI0000D5745C Cluster: PREDICTED: similar to Probable c...   110   1e-22
UniRef50_UPI000038CD69 Cluster: COG2124: Cytochrome P450; n=1; N...   110   1e-22
UniRef50_A5NX46 Cluster: Cytochrome P450; n=2; Alphaproteobacter...   110   1e-22
UniRef50_A1CS83 Cluster: NADPH cytochrome P450; n=1; Aspergillus...   110   1e-22
UniRef50_Q5UXK0 Cluster: Cytochrome P450; n=1; Haloarcula marism...   110   1e-22
UniRef50_UPI0000E49222 Cluster: PREDICTED: similar to CYP4BB1 is...   109   1e-22
UniRef50_Q121J8 Cluster: Cytochrome P450; n=2; Comamonadaceae|Re...   109   1e-22
UniRef50_Q9LUD2 Cluster: Cytochrome P450; n=6; core eudicotyledo...   109   1e-22
UniRef50_Q94EV6 Cluster: Cytochrome P450; n=19; Poaceae|Rep: Cyt...   109   1e-22
UniRef50_A5HKL8 Cluster: Cytochrome P450 CYP9A22; n=5; Ditrysia|...   109   1e-22
UniRef50_P30608 Cluster: Cytochrome P450 52A6; n=19; Saccharomyc...   109   1e-22
UniRef50_Q9Y6A2 Cluster: Cytochrome P450 46A1; n=22; Amniota|Rep...   109   1e-22
UniRef50_A6G6Z8 Cluster: Cytochrome P450; n=1; Plesiocystis paci...   109   2e-22
UniRef50_A0Y8J6 Cluster: Probable bifunctional P-450:NADPH-P450 ...   109   2e-22
UniRef50_Q2GUJ4 Cluster: Putative uncharacterized protein; n=2; ...   109   2e-22
UniRef50_Q0U771 Cluster: Putative uncharacterized protein; n=3; ...   109   2e-22
UniRef50_UPI0000D56E81 Cluster: PREDICTED: similar to Probable c...   109   2e-22
UniRef50_Q5KSN6 Cluster: Putative P450; n=1; Streptomyces sp. KO...   109   2e-22
UniRef50_A1W125 Cluster: Cytochrome P450 family protein; n=12; C...   109   2e-22
UniRef50_A2XB72 Cluster: Putative uncharacterized protein; n=2; ...   109   2e-22
UniRef50_A1DAX0 Cluster: Cytochrome P450; n=5; Trichocomaceae|Re...   109   2e-22
UniRef50_Q964Q7 Cluster: Cytochrome P450 6d3; n=9; Schizophora|R...   109   2e-22
UniRef50_Q9Y0E3 Cluster: Cytochrome P450; n=4; Culicidae|Rep: Cy...   108   3e-22
UniRef50_Q0GK98 Cluster: Cytochrome P450 CYP3-like member 4; n=3...   108   3e-22
UniRef50_Q9V675 Cluster: Probable cytochrome P450 6g2; n=2; Soph...   108   3e-22
UniRef50_Q4CB21 Cluster: Cytochrome P450; n=1; Crocosphaera wats...   108   4e-22
UniRef50_Q9SCP8 Cluster: Cytochrom P450-like protein; n=12; Magn...   108   4e-22
UniRef50_A5YU14 Cluster: CYP97A5; n=4; Chlorophyta|Rep: CYP97A5 ...   108   4e-22
UniRef50_UPI0000D577EE Cluster: PREDICTED: similar to Probable c...   107   6e-22
UniRef50_Q10ZS2 Cluster: Cytochrome P450; n=1; Trichodesmium ery...   107   6e-22
UniRef50_A7DAQ3 Cluster: Cytochrome P450; n=2; Methylobacterium ...   107   6e-22
UniRef50_A1XEM0 Cluster: CYP82E8; n=22; Nicotiana|Rep: CYP82E8 -...   107   6e-22
UniRef50_Q9BID3 Cluster: Cytochrome P450; n=2; Anopheles gambiae...   107   6e-22
UniRef50_UPI0000DB77A2 Cluster: PREDICTED: similar to Probable c...   107   8e-22
UniRef50_UPI0000DB76BC Cluster: PREDICTED: similar to Probable c...   107   8e-22
UniRef50_UPI0000D559EB Cluster: PREDICTED: similar to Probable c...   107   8e-22
UniRef50_Q8YQS3 Cluster: Cytochrome P450; n=7; Cyanobacteria|Rep...   107   8e-22
UniRef50_Q0S645 Cluster: Cytochrome P450 CYP136; n=4; Actinomyce...   107   8e-22
UniRef50_Q0DIA1 Cluster: Os05g0405500 protein; n=4; Oryza sativa...   107   8e-22
UniRef50_Q6JEK3 Cluster: 14a demethylase; n=1; Strongylocentrotu...   107   8e-22
UniRef50_Q0CI06 Cluster: Cytochrome P450 52; n=3; Aspergillus|Re...   107   1e-21
UniRef50_P82711 Cluster: Probable cytochrome P450 6a19; n=11; Dr...   107   1e-21
UniRef50_A4A9V8 Cluster: Cytochrome P450; n=4; Bacteria|Rep: Cyt...   106   1e-21
UniRef50_Q9VHP4 Cluster: Probable cytochrome P450 313b1; n=2; So...   106   1e-21
UniRef50_UPI0000DB7562 Cluster: PREDICTED: similar to Probable c...   106   2e-21
UniRef50_Q4BVN8 Cluster: Cytochrome P450; n=4; Cyanobacteria|Rep...   106   2e-21
UniRef50_Q9P493 Cluster: Cytochrome P-450 cyp509A1; n=1; Cunning...   106   2e-21
UniRef50_P24557 Cluster: Thromboxane-A synthase; n=40; Tetrapoda...   106   2e-21
UniRef50_P77900 Cluster: Putative cytochrome P450 132; n=8; Myco...   106   2e-21
UniRef50_UPI0000E4A8EA Cluster: PREDICTED: similar to GA15235-PA...   105   2e-21
UniRef50_Q0ASD0 Cluster: Cytochrome P450; n=1; Maricaulis maris ...   105   2e-21
UniRef50_A4S2Q7 Cluster: Predicted protein; n=2; Ostreococcus|Re...   105   2e-21
UniRef50_A3B3X2 Cluster: Putative uncharacterized protein; n=3; ...   105   2e-21
UniRef50_A2WPP2 Cluster: Putative uncharacterized protein; n=3; ...   105   2e-21
UniRef50_Q5XNT0 Cluster: Cytochrome P450; n=4; Culicidae|Rep: Cy...   105   2e-21
UniRef50_Q2UI50 Cluster: Cytochrome P450 CYP4/CYP19/CYP26 subfam...   105   2e-21
UniRef50_Q9V776 Cluster: Probable cytochrome P450 317a1; n=3; So...   105   2e-21
UniRef50_UPI0000E4A41F Cluster: PREDICTED: hypothetical protein;...   105   3e-21
UniRef50_A6FXD3 Cluster: Cytochrome P450 family protein; n=1; Pl...   105   3e-21
UniRef50_Q4Q2L1 Cluster: Cytochrome p450-like protein; n=4; Leis...   105   3e-21
UniRef50_Q1ZXL9 Cluster: Cytochrome P450 family protein; n=2; Di...   105   3e-21
UniRef50_P0A513 Cluster: Cytochrome P450 51; n=19; Corynebacteri...   105   3e-21
UniRef50_Q1I2J9 Cluster: Putative cytochrome P450; n=1; Pseudomo...   105   4e-21
UniRef50_P98186 Cluster: Cytochrome P450; n=1; Rhipicephalus mic...   105   4e-21
UniRef50_Q5B6B3 Cluster: Cytochrome P450 52; n=5; Eurotiomycetid...   105   4e-21
UniRef50_Q4H2B4 Cluster: Cytochrome P450 monooxygenase; n=2; Bas...   105   4e-21
UniRef50_A7F687 Cluster: Putative uncharacterized protein; n=2; ...   105   4e-21
UniRef50_Q9VS78 Cluster: Probable cytochrome P450 316a1; n=2; So...   105   4e-21
UniRef50_A6GCY6 Cluster: Cytochrome P450; n=1; Plesiocystis paci...   104   5e-21
UniRef50_A4BWJ8 Cluster: Cytochrome P450; n=6; Bacteroidetes|Rep...   104   5e-21
UniRef50_Q9LXX7 Cluster: Cytochrome P450-like protein; n=8; Magn...   104   5e-21
UniRef50_Q54ZM4 Cluster: Cytochrome P450 family protein; n=2; Di...   104   5e-21
UniRef50_Q5AR62 Cluster: Putative uncharacterized protein; n=1; ...   104   5e-21
UniRef50_A4BAW7 Cluster: Possible cytochrome P450 family protein...   104   7e-21
UniRef50_Q9LUC8 Cluster: Cytochrome P450; n=84; Magnoliophyta|Re...   104   7e-21
UniRef50_Q5XNU3 Cluster: Cytochrome P450; n=7; Culicidae|Rep: Cy...   104   7e-21
UniRef50_A7S7K8 Cluster: Predicted protein; n=1; Nematostella ve...   104   7e-21
UniRef50_O43174 Cluster: Cytochrome P450 26A1; n=40; Euteleostom...   104   7e-21
UniRef50_A6CJ44 Cluster: Cytochrome P450 hydroxylase; n=1; Bacil...   103   9e-21
UniRef50_Q10S04 Cluster: Cytochrome P450 family protein; n=9; Or...   103   9e-21
UniRef50_UPI00015B4ED4 Cluster: PREDICTED: similar to cytochrome...   103   1e-20
UniRef50_Q7SXE6 Cluster: LOC402831 protein; n=17; Euteleostomi|R...   103   1e-20
UniRef50_Q8GBX2 Cluster: Cytochrome-P450-monooxygenase; n=1; Sor...   103   1e-20
UniRef50_Q1EDA8 Cluster: HctH; n=1; Lyngbya majuscula|Rep: HctH ...   103   1e-20
UniRef50_Q2HDU4 Cluster: Cytochrome P450 52; n=5; Pezizomycotina...   103   1e-20
UniRef50_UPI0000D9A6B6 Cluster: PREDICTED: similar to Cytochrome...   103   2e-20
UniRef50_Q5Z0Q8 Cluster: Cytochrome P450 monooxygenase; n=6; Cor...   103   2e-20
UniRef50_Q2J4I2 Cluster: Cytochrome P450; n=2; Frankia|Rep: Cyto...   103   2e-20
UniRef50_Q1GGM8 Cluster: Cytochrome P450; n=23; cellular organis...   103   2e-20
UniRef50_A3IXI8 Cluster: Cytochrome P450; n=1; Cyanothece sp. CC...   103   2e-20
UniRef50_A4R1C8 Cluster: Putative uncharacterized protein; n=1; ...   103   2e-20
UniRef50_A1D653 Cluster: Cytochrome P450 52; n=1; Neosartorya fi...   103   2e-20
UniRef50_Q9VRI9 Cluster: Probable cytochrome P450 6t1; n=1; Dros...   103   2e-20
UniRef50_UPI0000D56E84 Cluster: PREDICTED: similar to Probable c...   102   2e-20
UniRef50_Q09D70 Cluster: Putative cytochrome P450 135A1; n=1; St...   102   2e-20
UniRef50_Q9FHC0 Cluster: Cytochrome P-450-like protein; n=5; Mag...   102   2e-20
UniRef50_Q86QN2 Cluster: Cytochrome P450 CYP12F1; n=15; Culicida...   102   2e-20
UniRef50_Q3I417 Cluster: Cytochrome P450; n=4; Cucujiformia|Rep:...   102   2e-20
UniRef50_Q17GV0 Cluster: Cytochrome P450; n=4; Aedes aegypti|Rep...   102   2e-20
UniRef50_Q56VS2 Cluster: Cytochrome P450 monooxygenase pc-3; n=2...   102   2e-20
UniRef50_Q1DZ64 Cluster: Cytochrome P450 52; n=4; Eurotiomycetid...   102   2e-20
UniRef50_Q0LHR9 Cluster: Cytochrome P450; n=1; Herpetosiphon aur...   102   3e-20
UniRef50_Q5XM71 Cluster: Cytochrome P450; n=2; Anopheles gambiae...   102   3e-20
UniRef50_A0BYI6 Cluster: Chromosome undetermined scaffold_137, w...   102   3e-20
UniRef50_UPI00015B5A0F Cluster: PREDICTED: similar to cytochrome...   101   4e-20
UniRef50_Q0VLW6 Cluster: Cytochrome P450, putative; n=1; Alcaniv...   101   4e-20
UniRef50_A6FYS5 Cluster: Possible cytochrome P450 hydroxylase su...   101   4e-20
UniRef50_Q9FF18 Cluster: Cytochrome P450-like protein; n=9; Magn...   101   4e-20
UniRef50_A7Q635 Cluster: Chromosome undetermined scaffold_55, wh...   101   4e-20
UniRef50_Q2TZX1 Cluster: Cytochrome P450 CYP3/CYP5/CYP6/CYP9 sub...   101   4e-20
UniRef50_A1C9K9 Cluster: Cytochrome P450 52; n=1; Aspergillus cl...   101   4e-20
UniRef50_A6G8E6 Cluster: Cytochrome P450; n=1; Plesiocystis paci...   101   5e-20
UniRef50_Q93VK5 Cluster: At1g31800/68069_m00159; n=12; Magnoliop...   101   5e-20
UniRef50_A7PDZ0 Cluster: Chromosome chr11 scaffold_13, whole gen...   101   5e-20
UniRef50_A2YQ01 Cluster: Putative uncharacterized protein; n=3; ...   101   5e-20
UniRef50_Q27693 Cluster: Cytochrome P450; n=2; Musca domestica|R...   101   5e-20
UniRef50_Q16FQ2 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep...   101   5e-20
UniRef50_A6SJT7 Cluster: Cytochrome P450 52; n=2; Sclerotiniacea...   101   5e-20
UniRef50_Q9SD85 Cluster: Flavonoid 3'-monooxygenase; n=66; Magno...   101   5e-20
UniRef50_Q9VYT8 Cluster: Probable cytochrome P450 28c1; n=7; Sop...   101   5e-20
UniRef50_UPI00015B6122 Cluster: PREDICTED: similar to cytochrome...   101   7e-20
UniRef50_Q11B49 Cluster: Cytochrome P450; n=8; Rhizobiales|Rep: ...   101   7e-20
UniRef50_A5VF31 Cluster: Cytochrome P450; n=2; Sphingomonas|Rep:...   101   7e-20
UniRef50_A1ZCF9 Cluster: Cytochrome P450, putative; n=1; Microsc...   101   7e-20
UniRef50_Q7Y222 Cluster: Putative cytochrome p450; n=1; Arabidop...   101   7e-20
UniRef50_A7S334 Cluster: Predicted protein; n=3; Nematostella ve...   101   7e-20
UniRef50_Q8NJK3 Cluster: Cytochrome P450 monooxygenase pc-2; n=7...   101   7e-20
UniRef50_A6S9P2 Cluster: Cytochrome P450 52; n=2; Sclerotiniacea...   101   7e-20
UniRef50_A4RFM7 Cluster: Putative uncharacterized protein; n=1; ...   101   7e-20
UniRef50_O48927 Cluster: Cytochrome P450 78A3; n=7; core eudicot...   101   7e-20
UniRef50_UPI00015B5A10 Cluster: PREDICTED: similar to cytochrome...   100   9e-20
UniRef50_UPI0000E46525 Cluster: PREDICTED: similar to cytochrome...   100   9e-20
UniRef50_Q2L6E2 Cluster: P450; n=1; Streptomyces sp. KO-3988|Rep...   100   9e-20
UniRef50_Q50EK3 Cluster: Cytochrome P450 CYPD; n=5; Spermatophyt...   100   9e-20
UniRef50_Q0D4C4 Cluster: Os07g0635300 protein; n=10; Oryza sativ...   100   9e-20
UniRef50_Q0UKV8 Cluster: Putative uncharacterized protein; n=1; ...   100   9e-20
UniRef50_Q9AXM6 Cluster: Taxane 10-beta-hydroxylase; n=16; Eukar...   100   9e-20
UniRef50_Q16850 Cluster: Cytochrome P450 51A1; n=36; Euteleostom...   100   9e-20
UniRef50_UPI00015B569B Cluster: PREDICTED: similar to cytochrome...   100   1e-19
UniRef50_Q0Z7A9 Cluster: Cytochrome p450; n=1; Synechococcus sp....   100   1e-19
UniRef50_A6WEH8 Cluster: Cytochrome P450; n=1; Kineococcus radio...   100   1e-19
UniRef50_A2YMR4 Cluster: Putative uncharacterized protein; n=3; ...   100   1e-19
UniRef50_Q58QP8 Cluster: Cytochrome P450; n=1; Mayetiola destruc...   100   1e-19
UniRef50_A5JTS8 Cluster: Cytochrome P450; n=7; Ditrysia|Rep: Cyt...   100   1e-19
UniRef50_A7F1G0 Cluster: Putative uncharacterized protein; n=1; ...   100   1e-19
UniRef50_A4RLQ3 Cluster: Cytochrome P450 52; n=1; Magnaporthe gr...   100   1e-19
UniRef50_A7PEY9 Cluster: Chromosome chr11 scaffold_13, whole gen...    99   2e-19
UniRef50_A7RT69 Cluster: Predicted protein; n=1; Nematostella ve...    99   2e-19
UniRef50_Q2HFV6 Cluster: Putative uncharacterized protein; n=1; ...    99   2e-19
UniRef50_A1CK35 Cluster: Fatty acid hydroxylase, putative; n=7; ...    99   2e-19
UniRef50_Q9V6H1 Cluster: Probable cytochrome P450 9h1; n=3; Soph...    99   2e-19
UniRef50_Q08QP6 Cluster: Cytochrome P450; n=1; Stigmatella auran...   100   2e-19
UniRef50_A3ADU7 Cluster: Putative uncharacterized protein; n=3; ...   100   2e-19
UniRef50_A0A8M4 Cluster: Cytochrome P450 314 family; n=1; Daphni...   100   2e-19
UniRef50_Q2UT03 Cluster: Cytochrome P450 52; n=6; Trichocomaceae...   100   2e-19
UniRef50_P95099 Cluster: Putative cytochrome P450 136; n=15; Myc...   100   2e-19
UniRef50_UPI00015B595E Cluster: PREDICTED: similar to cytochrome...    99   3e-19
UniRef50_UPI0000D55B02 Cluster: PREDICTED: similar to Probable c...    99   3e-19
UniRef50_Q6NCP8 Cluster: Possible cytochrome P450 hydroxylase su...    99   3e-19
UniRef50_Q5YMA8 Cluster: Cytochrome P450 monooxygenase; n=1; Noc...    99   3e-19
UniRef50_Q39NW6 Cluster: Cytochrome P450; n=1; Burkholderia sp. ...    99   3e-19
UniRef50_A4FKX0 Cluster: Cytochrome P450; n=1; Saccharopolyspora...    99   3e-19
UniRef50_Q2LAK7 Cluster: Cytochrome P450 monooxygenase CYP72A67;...    99   3e-19
UniRef50_Q5ARQ0 Cluster: Putative uncharacterized protein; n=1; ...    99   3e-19
UniRef50_A1CIZ0 Cluster: Cytochrome P450; n=1; Aspergillus clava...    99   3e-19
UniRef50_A1C5L5 Cluster: Cytochrome P450 oxidoreductase, putativ...    99   3e-19
UniRef50_UPI000023DC99 Cluster: hypothetical protein FG02366.1; ...    99   4e-19
UniRef50_Q9LSF8 Cluster: Cytochrome p450; n=2; Arabidopsis thali...    99   4e-19
UniRef50_A5BGU6 Cluster: Putative uncharacterized protein; n=1; ...    99   4e-19
UniRef50_Q8WQN0 Cluster: Cytochrome P450 CYP6S2; n=6; Culicidae|...    99   4e-19
UniRef50_Q174T2 Cluster: Cytochrome P450; n=13; Aedes aegypti|Re...    99   4e-19
UniRef50_Q9VWR2 Cluster: Probable cytochrome P450 308a1; n=2; So...    99   4e-19
UniRef50_UPI00005842DC Cluster: PREDICTED: similar to CYP2A13 pr...    98   5e-19
UniRef50_A7PQ74 Cluster: Chromosome chr18 scaffold_24, whole gen...    98   5e-19
UniRef50_A1XEH2 Cluster: CYP82M1v1; n=5; Nicotiana tabacum|Rep: ...    98   5e-19
UniRef50_Q2TWI0 Cluster: Cytochrome P450 52; n=2; Pezizomycotina...    98   5e-19
UniRef50_UPI00015B480D Cluster: PREDICTED: similar to cytochrome...    98   6e-19
UniRef50_UPI00015B46F7 Cluster: PREDICTED: similar to Cyp6g1; n=...    98   6e-19
UniRef50_A7U483 Cluster: Cytochrome P450 family 17 polypeptide 2...    98   6e-19
UniRef50_Q9SJH2 Cluster: Putative cytochrome P450; n=1; Arabidop...    98   6e-19
UniRef50_Q9LN32 Cluster: F18O14.38; n=5; core eudicotyledons|Rep...    98   6e-19
UniRef50_Q22Z86 Cluster: Cytochrome P450 family protein; n=1; Te...    98   6e-19
UniRef50_A7SKW0 Cluster: Predicted protein; n=6; Nematostella ve...    98   6e-19
UniRef50_Q2U4F1 Cluster: Cytochrome P450; n=1; Aspergillus oryza...    98   6e-19
UniRef50_A2QLV1 Cluster: Contig An06c0110, complete genome; n=3;...    98   6e-19
UniRef50_Q9V674 Cluster: Cytochrome P450 6g1; n=16; Schizophora|...    98   6e-19
UniRef50_UPI000058466C Cluster: PREDICTED: similar to cytochrome...    97   8e-19
UniRef50_Q9ZW95 Cluster: F5A8.3 protein; n=1; Arabidopsis thalia...    97   8e-19
UniRef50_Q9SZ46 Cluster: Cytochrome P450-like protein; n=11; cor...    97   8e-19

>UniRef50_Q9VYY4 Cluster: Cytochrome P450 4g15; n=8; Neoptera|Rep:
           Cytochrome P450 4g15 - Drosophila melanogaster (Fruit
           fly)
          Length = 574

 Score =  745 bits (1841), Expect = 0.0
 Identities = 365/563 (64%), Positives = 432/563 (76%), Gaps = 30/563 (5%)

Query: 16  SAINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRN 75
           S  ++FY LL+P ++LWY YWR+SR  LY LA +L          +  + +G ++ +FR 
Sbjct: 12  SPSSVFYFLLLPTLVLWYIYWRLSRAHLYRLAGRLPGPRGLPIVGHLFDVIGPASSVFRT 71

Query: 76  IVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLL 135
           +++KSA ++H  + K+WIGP+L+VF+YDPRDVE++LSSHVYIDKA EY+FFKPWLG+GLL
Sbjct: 72  VIRKSAPFEH--IAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKPWLGDGLL 129

Query: 136 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE-ASNFDCHDYMSECTV 194
           ISTGQKWRSHRKLIAPTFHLNVLKSFI+LFN NSR VV KL+ E    FDCHDYMSE TV
Sbjct: 130 ISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGRTFDCHDYMSEATV 189

Query: 195 EILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKL 254
           EILLETAMGVSK TQD+SGFEYAMAVM+MCDILH RH  I+LR + +F  T Y K Q +L
Sbjct: 190 EILLETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYYKEQGRL 249

Query: 255 LDIIHGLTKKVIKRKKEEFASGKKPS-------------------NLNETATTS------ 289
           L+IIHGLT KVI+ KK  F  G + S                    +++T +T+      
Sbjct: 250 LNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKD 309

Query: 290 -EPSTGKLTSVEGLSFGQSSGLKXXXXXXXXX-GQKKRLAFLDLLLESSQSGVAISDEEI 347
            E    K + V GLS+GQS+GLK          G+KKRLAFLDL+LES+Q+G  I+D EI
Sbjct: 310 REKDKEKASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLMLESAQNGALITDTEI 369

Query: 348 KEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMK 407
           KEQVDTIMFEGHDTTAAGSSFFLS+MGIHQDIQD+V+ ELD IFGDS RP TFQDTLEMK
Sbjct: 370 KEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQDTLEMK 429

Query: 408 YLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPN 467
           YLERCLMETLR+YPPVP+IAR++ +++ L S    IP G T+ +AT  LHR P VY NPN
Sbjct: 430 YLERCLMETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPN 489

Query: 468 KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKES 527
            FDPDNFLPER ANRHYYAFVPFSAGPRSCVGRKYAMLKLK++LSTILRN+RV SDL ES
Sbjct: 490 VFDPDNFLPERQANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTES 549

Query: 528 DFKLQADIILKRAEGFQVRLQPR 550
           DFKLQADIILKR EGF+VRLQPR
Sbjct: 550 DFKLQADIILKREEGFRVRLQPR 572


>UniRef50_Q9V3S0 Cluster: Cytochrome P450 4g1; n=62;
           Protostomia|Rep: Cytochrome P450 4g1 - Drosophila
           melanogaster (Fruit fly)
          Length = 556

 Score =  508 bits (1254), Expect = e-142
 Identities = 253/466 (54%), Positives = 331/466 (71%), Gaps = 12/466 (2%)

Query: 89  VKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148
           +K W+G  LLVFL +P D+E+ILS H ++ KAEEYR+FKPW G+GLLIS G  WR HRK+
Sbjct: 95  MKAWLGNVLLVFLTNPSDIELILSGHQHLTKAEEYRYFKPWFGDGLLISNGHHWRHHRKM 154

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS-NFDCHDYMSECTVEILLETAMGVSKS 207
           IAPTFH ++LKSF+  F  +S+AVV ++  EA  +FD HDYMS+ TV+ILL TAMGV K 
Sbjct: 155 IAPTFHQSILKSFVPTFVDHSKAVVARMGLEAGKSFDVHDYMSQTTVDILLSTAMGVKKL 214

Query: 208 TQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIK 267
            +    FEYA AV+ MCDI+H R  K+  R D ++KFT   +   ++++II G+T KV+K
Sbjct: 215 PEGNKSFEYAQAVVDMCDIIHKRQVKLLYRLDSIYKFTKLREKGDRMMNIILGMTSKVVK 274

Query: 268 RKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLA 327
            +KE F    +   + E  +T   ST   +  EGL                  G K+RLA
Sbjct: 275 DRKENFQEESRA--IVEEISTPVAST-PASKKEGLRDDLDD------IDENDVGAKRRLA 325

Query: 328 FLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
            LD ++E +++  +  ++++I ++V+TIMFEGHDTT+AGSSF L MMGIH+DIQ KV  E
Sbjct: 326 LLDAMVEMAKNPDIEWNEKDIMDEVNTIMFEGHDTTSAGSSFALCMMGIHKDIQAKVFAE 385

Query: 387 LDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445
              IFGD+  R  TF DT+EMKYLER ++ETLRLYPPVP+IAR+++ ++ L S    +P 
Sbjct: 386 QKAIFGDNMLRDCTFADTMEMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPK 445

Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505
           GTT+++  Y +HRRPD+YPNP KFDPDNFLPER ANRHYY+F+PFSAGPRSCVGRKYAML
Sbjct: 446 GTTVIVLQYCVHRRPDIYPNPTKFDPDNFLPERMANRHYYSFIPFSAGPRSCVGRKYAML 505

Query: 506 KLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           KLKV+LSTI+RN+ V S   E+DFKLQADIILK   GF V L+ R+
Sbjct: 506 KLKVLLSTIVRNYIVHSTDTEADFKLQADIILKLENGFNVSLEKRQ 551


>UniRef50_Q967Y5 Cluster: Cytochrome P450 CYP4G13v2; n=4;
           Neoptera|Rep: Cytochrome P450 CYP4G13v2 - Musca
           domestica (House fly)
          Length = 552

 Score =  480 bits (1183), Expect = e-134
 Identities = 245/535 (45%), Positives = 346/535 (64%), Gaps = 15/535 (2%)

Query: 20  LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNA-LEFVGGSADIFRNIVQ 78
           L  V  V  + + Y Y+R + R  Y+L D +          N  + F   +  I + + Q
Sbjct: 24  LSLVFGVGVIAILYEYYRRNTRA-YKLMDTIPTPKQMPLIGNGHMAFGQNNHQILKLMSQ 82

Query: 79  KSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST 138
              D      V+I +G   +VFL +P D+E+ L+ + +++K+ EYR+F+PW GNGLLIS 
Sbjct: 83  VFKDCGE--TVRILLGHMNVVFLTNPADLEIFLNGYKHLEKSVEYRYFQPWFGNGLLISK 140

Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKL-KKEASNFDCHDYMSECTVEIL 197
           G  WR HRK+IAPTFH ++LKSF+  F  +S+AV  +   K    FDCH YMSE TV+IL
Sbjct: 141 GHHWRHHRKMIAPTFHQSILKSFVPTFVKHSKAVSGRFASKVGQEFDCHKYMSETTVDIL 200

Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257
           L TAMG     + +   EYA AVM MCDI+H+R  K++ R D   +FT   ++  KL+++
Sbjct: 201 LTTAMGCKVQPETEKSAEYAQAVMDMCDIIHIRQLKLFYRLDSTIRFTKLREHDNKLMNV 260

Query: 258 IHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXX 317
           I  +T+KV++ +K+ F + ++   ++ TA  ++    K    EGL               
Sbjct: 261 ILSMTRKVVEDRKKNF-NAEERGIVDRTAEDAKLKA-KAAKKEGLRDDLDD------IDE 312

Query: 318 XXXGQKKRLAFLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 376
              G+K+RLA LD ++E  ++  +  +D+++ ++V+TIMFEGHDTTAAGSSF L M+GIH
Sbjct: 313 NDIGEKRRLALLDAMMEMEKNPDIKWTDKDVMDEVNTIMFEGHDTTAAGSSFALCMLGIH 372

Query: 377 QDIQDKVIEELDQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEIT 435
           QD+Q +V EE   IFGD  +R  TF DTL+M YLER + ET RL+PPVP+IAR+  +++ 
Sbjct: 373 QDVQQRVFEEQQAIFGDDLNRDCTFADTLQMSYLERVICETQRLFPPVPLIARKAEEDVN 432

Query: 436 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495
           L S    I  GTT+V+  Y +HRR D+YP+P KF+PDNFLPER+ANRHYYA++PFSAGPR
Sbjct: 433 LKSGPYTIAKGTTVVLLQYFVHRRADIYPDPEKFNPDNFLPERTANRHYYAYIPFSAGPR 492

Query: 496 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           SCVGRK+AML+LKV+LSTI+RN+RV S   + DF+LQ DIILK A GF + L+ R
Sbjct: 493 SCVGRKFAMLQLKVLLSTIIRNYRVSSTRTQKDFQLQGDIILKMANGFNITLEKR 547


>UniRef50_Q16ML8 Cluster: Cytochrome P450; n=3; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 509

 Score =  381 bits (938), Expect = e-104
 Identities = 208/534 (38%), Positives = 306/534 (57%), Gaps = 37/534 (6%)

Query: 22  YVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSA-DIFRNIVQKS 80
           Y +LV  +   +  W + R RL ++ DK+              F G    ++F  I +++
Sbjct: 9   YGILVFLIFAPFLQWWVKRARLVQIIDKIPGPKAYPFIGTTYTFFGKKHYELFYIIDERT 68

Query: 81  ADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQ 140
             Y    + +IW G R  + +  P  VE I+ +  +++K+  Y F   WLG GLL S G+
Sbjct: 69  RRYP--DIHRIWTGMRPEIRISKPEYVETIIGASKHMEKSHGYDFLFDWLGEGLLTSKGE 126

Query: 141 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 197
           +W  HRKLI PTFH N+L  F D+F      + ++L+  A+     D   ++++  ++I+
Sbjct: 127 RWFQHRKLITPTFHFNILDGFCDVFAEQGAVLAERLEPFANTGKPVDVFPFITKAALDII 186

Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257
            ETAMGV  + Q      Y  A+ +M +I   R  K WL P+ +FK T+Y +   K LDI
Sbjct: 187 CETAMGVKVNAQTGGENNYVNAIYRMSEIFVDRSIKPWLHPEFIFKRTEYGRQHKKALDI 246

Query: 258 IHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXX 317
           +HG TKKVI+ +KE                  E STG   + E L FG            
Sbjct: 247 VHGYTKKVIRDRKEALQ-------------VKENSTGAGDTGEDLYFGT----------- 282

Query: 318 XXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 377
                KKRLAFLDLLLE +     ++D++++E+VDT MFEGHDTT AG S+ L ++G+H 
Sbjct: 283 -----KKRLAFLDLLLEGNAKHKQLTDDDVREEVDTFMFEGHDTTTAGMSWALFLLGLHP 337

Query: 378 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 437
           D QD+V +E+D IF  SDRP T +D  EMK LERCL ETLRLYP V    R++++++TL 
Sbjct: 338 DWQDRVHQEIDSIFAGSDRPATMKDLGEMKLLERCLKETLRLYPSVSFFGRKLSEDVTL- 396

Query: 438 SNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 497
                IPAGT + I  Y +HR    YP+P KFDPD FLPE + +RH +A++PFSAGPR+C
Sbjct: 397 -GQYHIPAGTLMGIHAYHVHRDERFYPDPEKFDPDRFLPENTEHRHPFAYIPFSAGPRNC 455

Query: 498 VGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           +G+K+A+L+ K I+S++LR FRV S     + K+  ++I +  EG ++ L+ R+
Sbjct: 456 IGQKFAILEEKSIVSSVLRKFRVRSANTRDEQKICQELITRPNEGIRLYLEKRQ 509


>UniRef50_A0A8M5 Cluster: Cytochrome P450 4 family; n=1; Daphnia
           magna|Rep: Cytochrome P450 4 family - Daphnia magna
          Length = 526

 Score =  369 bits (908), Expect = e-100
 Identities = 189/468 (40%), Positives = 283/468 (60%), Gaps = 33/468 (7%)

Query: 88  VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 147
           +++ WIGP  + F      VE +LSS+  I K+ EY F  PWL  GLL STG KW++ RK
Sbjct: 88  IIRAWIGPLPMFFATTAEAVEAVLSSNKIITKSREYDFLHPWLNTGLLTSTGSKWQTRRK 147

Query: 148 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS---NFDCHDYMSECTVEILLETAMGV 204
           L+ P FH  +L+ F+ +FN  S  +V+KL +  +   + +   +++ CT++I+ ETAMG 
Sbjct: 148 LLTPAFHFKILEDFVHVFNEQSLILVNKLNQAVAKDKDLNIFPFVTLCTLDIICETAMGR 207

Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264
           +   Q ++   Y  AV  M  ++  R  + +L  D +FK + +   Q K L I+HG T K
Sbjct: 208 NVEAQSKTDSAYVQAVYNMSQLIQHRQVRFYLWLDWMFKLSSHWPEQRKTLGILHGFTNK 267

Query: 265 VIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKK 324
           VI+ +        K  +   ++  +EPS       E   F                  K+
Sbjct: 268 VIQER--------KAEHQQRSSDIAEPSKDV---TEDAVFS-----------------KR 299

Query: 325 RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVI 384
           RLAFLDLL+E SQ G  +S  +I+E+VDT MFEGHDTT+A  ++ + ++G H ++Q+ V 
Sbjct: 300 RLAFLDLLIEFSQGGTVLSASDIREEVDTFMFEGHDTTSAAITWSIFLIGSHPEVQEMVN 359

Query: 385 EELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIP 444
           EELD++FGDSDRP T  D  E+KYLE C+ E LRLYP VPII+R   ++  +   G +IP
Sbjct: 360 EELDRVFGDSDRPATMADLSELKYLECCVKEALRLYPSVPIISRTCVEDTVI--GGDEIP 417

Query: 445 AGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAM 504
           AGT++ I +Y LHR P  +P+P  + P  FL E +  RH Y++VPFSAGPR+C+G+++A+
Sbjct: 418 AGTSVSICSYYLHRDPKYFPDPELYQPKRFLAEHAERRHPYSYVPFSAGPRNCIGQRFAL 477

Query: 505 LKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552
           ++ K +LS ILRNF V S  K  +  L A++IL+  +G +VRL+P+K+
Sbjct: 478 MEEKAVLSAILRNFHVQSLDKREEIILLAELILRPRDGIRVRLEPKKK 525


>UniRef50_O76478 Cluster: Corpora allata cytochrome P450; n=2;
           Neoptera|Rep: Corpora allata cytochrome P450 -
           Diploptera punctata (Pacific beetle cockroach)
          Length = 497

 Score =  347 bits (854), Expect = 3e-94
 Identities = 191/493 (38%), Positives = 287/493 (58%), Gaps = 38/493 (7%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120
           N+L   G   + FR + + +  Y +  + ++W+G R  VFLY    ++ IL+S VYIDK+
Sbjct: 39  NSLILRGTQEEFFRLLSKCATKYGN--IFRLWVGQRPFVFLYSAEAIQPILNSTVYIDKS 96

Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180
            EY F  PWLG GLL STG KW + RKL+  +FH  VL+ F++    +S  + ++L+ E 
Sbjct: 97  YEYSFLFPWLGTGLLTSTGNKWHTRRKLLTQSFHSKVLEDFLEPIYQHSLFLCNRLELEL 156

Query: 181 S--NFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRP 238
              +F    Y   C ++I+ +TAMG + + Q+ S  EY  AV  + +I+  R    WL+P
Sbjct: 157 DKPHFKVTPYAKLCALDIICDTAMGSTINAQENSQSEYVTAVDSLSEIVQRRFITPWLKP 216

Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTS 298
           D LFK T   K Q + L I+H  T+KVI  +KE+     + +NL                
Sbjct: 217 DFLFKMTKLGKKQEQCLKIVHNFTRKVINERKEDKL---RQNNLE--------------- 258

Query: 299 VEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEG 358
              +   Q +G+K          +K RLA LDLLLE S++G  ++DE+I E+VDT MF G
Sbjct: 259 ---VEISQQNGIK----------KKHRLALLDLLLELSENGKVLTDEDICEEVDTFMFAG 305

Query: 359 HDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETL 417
           HDT A+G S+ L ++G H D Q+K++EE   +   D+    T +   ++ YLERC+ E +
Sbjct: 306 HDTIASGVSWILYVLGHHLDSQEKIVEEFKNVMEEDNTEWPTMKHLNKLCYLERCIKEAM 365

Query: 418 RLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPE 477
           RLYP VP+IAR + Q I +      +P G T++I TY LHR    +PNP+ F+PD FL  
Sbjct: 366 RLYPVVPLIARNLTQPIKIMDY--MLPEGVTILINTYLLHRDSRFFPNPDIFEPDRFLTS 423

Query: 478 RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIIL 537
               R+ +A+VPFSAGPR+C+G+K+AM++LK+ILST+L+ F V S  KE   KL  +++L
Sbjct: 424 NCEARNPFAYVPFSAGPRNCIGQKFAMMELKIILSTVLQRFIVKSVDKEERLKLVGELVL 483

Query: 538 KRAEGFQVRLQPR 550
              +G ++ +  R
Sbjct: 484 LNRDGIRLTITAR 496


>UniRef50_UPI00015B560A Cluster: PREDICTED: similar to cytochrome
           P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 543

 Score =  335 bits (823), Expect = 2e-90
 Identities = 194/540 (35%), Positives = 292/540 (54%), Gaps = 65/540 (12%)

Query: 42  RLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFL 101
           RLY  + K           NA  F+G + DI     Q+  D  + S  ++W+  RL   +
Sbjct: 30  RLYRESAKFPGPPALPFIGNAHFFMGSTEDILSKC-QELLD-TYPSPFRVWLADRLFYAV 87

Query: 102 YDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSF 161
           YDP  ++ I  S   I+K E Y+F +PWLG GL  +   KWR HRKLI PTF+  +L+SF
Sbjct: 88  YDPEQLKTIFLSPKTIEKEELYKFAEPWLGTGLFTAPASKWRIHRKLIMPTFNPRILESF 147

Query: 162 IDLFNANSRAVVDKLKKE--ASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMA 219
           +++F+  S  ++ +++ E     FD   Y+S CT++I+ ETAMGV    Q Q    Y  +
Sbjct: 148 VEVFSVQSEVMIKEMEVELNGGEFDIFHYVSLCTLDIICETAMGVRSRAQTQRNSPYVES 207

Query: 220 VMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKP 279
             ++ +I++ R  KIWL PD++F  T   K+Q + +  +H LT  VIKRKK+ F      
Sbjct: 208 AKRLFEIVYSRMFKIWLHPDIIFNNTRLGKDQRECIKYVHSLTDDVIKRKKQAF------ 261

Query: 280 SNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSG 339
               E   T E   GKL  VEG                      KR AFLDLL+E S  G
Sbjct: 262 ----EGNGTVEGMNGKLPQVEG----------------------KRKAFLDLLMELSHEG 295

Query: 340 VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRP-- 397
              +DEE++E+VDT+M  G+DTTA  + F + M+  H +IQDKV EEL +I+G  D    
Sbjct: 296 TKFTDEELREEVDTMMIAGNDTTATVNCFVMLMLASHPEIQDKVYEELCEIYGSEDPSSV 355

Query: 398 -VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN----------------- 439
            V  +D   M+YLER + ET+R++P  P++ R+V  ++ + ++                 
Sbjct: 356 LVRHEDLHRMEYLERVIKETMRIFPVGPVLVRRVTDDLNIGNHPLYFAIMNCNFDYINQI 415

Query: 440 -------GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 492
                     +  G+++V+   K HR  + + +P  F+PD FLPE  A RH Y ++PFSA
Sbjct: 416 CFYGITGDYTLTKGSSVVLGIIKTHRSEEYWTDPLTFNPDRFLPEECAKRHPYTYIPFSA 475

Query: 493 GPRSCVGRKYAMLKLKVILSTILRNFRVISD--LKESDFKLQADIILKRAEGFQVRLQPR 550
           GPR+C+G KYAM+ +K +L+T++R + +  D  L   D KL+AD++LK  E   +R++ R
Sbjct: 476 GPRNCLGMKYAMMAMKALLATVIRKYVIKKDNALPVQDIKLKADVMLKPVEPITIRIERR 535


>UniRef50_A7SWY9 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 509

 Score =  327 bits (803), Expect = 5e-88
 Identities = 178/496 (35%), Positives = 285/496 (57%), Gaps = 38/496 (7%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIG-PRLLVFLYDPRDVEVILSSHVYIDK 119
           N LEF    ++    I+   + +  + +  +W+   +  + +Y+P+ VEVILSS  +I K
Sbjct: 46  NTLEFKDEPSEFLEQIMGWCSQF--KGIFCLWLSFAKPFLLIYEPKTVEVILSSSKHITK 103

Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE 179
           A+ Y F  PWLG GLL STG+KW+  R+LI PTFH  +L  F+ +F+  S+ +V  +K +
Sbjct: 104 AQFYDFLLPWLGTGLLTSTGEKWKKRRRLITPTFHFKILNDFVQVFDQQSQLMVSIIKSQ 163

Query: 180 ASN--FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLR 237
            S+  F+    ++ C ++I+ +TAMGV+ + Q  S  EY   V++M +++  R  + W+ 
Sbjct: 164 PSDKVFNIFPLIACCALDIIGKTAMGVNINAQKNSSSEYVKGVIRMSELIQSRQKRPWVH 223

Query: 238 PDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLT 297
           P  L+  T+  +   K++  +H  T +VI  + +E      P   +ET  + E  TG+  
Sbjct: 224 PAFLYCLTNEGREHNKIIKFLHDFTNQVITERIQERLYS--PKEQDETEESDE-FTGR-- 278

Query: 298 SVEGLSFGQSSGLKXXXXXXXXXGQKKRL-AFLDLLLESSQSGVAISDEEIKEQVDTIMF 356
                                   +K+RL AFLD+LL +  +G  I  E ++E+VD  MF
Sbjct: 279 ------------------------RKRRLVAFLDMLLNAYDAG-EIDVEGVREEVDIFMF 313

Query: 357 EGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMET 416
           EGHDTTAA  ++ + ++G H D+Q K   E+D+ F  +   +T      +KYLE  + ET
Sbjct: 314 EGHDTTAAAMAWAVQLLGEHPDVQRKAQAEVDEFFATNSGKLTADSLKGLKYLECVIKET 373

Query: 417 LRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 476
           LR++P VP   R + +++ L   G+ IP GT + + T  LHR P+V+P+P KF+PD FLP
Sbjct: 374 LRIFPSVPFFGRSLVEDLEL--EGRLIPKGTDVGVITIGLHRNPEVWPSPMKFNPDRFLP 431

Query: 477 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADII 536
           E S  RH YAFVPFSAG R+C+G+++A+L+ KV+L+ IL NF ++S  K +  K  A++I
Sbjct: 432 ENSEGRHPYAFVPFSAGSRNCIGQRFALLEEKVVLAYILHNFDIVSTEKSTKIKTCAELI 491

Query: 537 LKRAEGFQVRLQPRKR 552
            +  +G  V L  R++
Sbjct: 492 TRPRDGIFVSLTTREQ 507


>UniRef50_A0MNW4 Cluster: Cyp4M9; n=20; Obtectomera|Rep: Cyp4M9 -
           Bombyx mandarina (Wild silk moth) (Wild silkworm)
          Length = 505

 Score =  313 bits (769), Expect = 7e-84
 Identities = 174/495 (35%), Positives = 280/495 (56%), Gaps = 33/495 (6%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120
           NAL+ +   A++F  + +K+A     ++ + W      + +Y P ++E I+SS  +I K+
Sbjct: 42  NALDVILSPAELFA-LTRKNAT-QWPNLNRFWSFGIGALNIYGPDEIEAIISSTQHITKS 99

Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-E 179
             Y F   WL +GLL+STG KW+  RK++ P FH N LK F  +   NS+   + LK  E
Sbjct: 100 PVYNFLSDWLRDGLLLSTGTKWQKRRKILTPAFHFNTLKQFCVILEENSQRFTENLKDTE 159

Query: 180 ASNFDCHDYMSECTVEILLETAMGVSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRP 238
             + +    +SE T+  + ETAM     ++  ++G  Y  A+ ++ +    R  +I    
Sbjct: 160 GKSINVVPAISEYTLHSICETAMRTQLGSETSEAGRSYKNAICELGNQFVHRLARIPPHN 219

Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTS 298
           + ++      K Q + L+I+H  TK+VI + + ++      +N ++   T          
Sbjct: 220 NFIYNLFTLGK-QNEHLNIVHSFTKRVI-KDRRQYIRRNGGNNFDDEKDTQADE------ 271

Query: 299 VEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEG 358
              + F                  KK+ A LDLLL++ + G+ I +  ++E++DT MFEG
Sbjct: 272 -HSIYFN-----------------KKKTAMLDLLLKAERDGL-IDEIGVQEEIDTFMFEG 312

Query: 359 HDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLR 418
           HDTTA G ++ + ++  H+ IQDK+IEELD+IFG+S R    +D  +M+YLERC+ E+LR
Sbjct: 313 HDTTATGLTYCIMLIANHKSIQDKIIEELDEIFGESTRAADIEDLSKMRYLERCIKESLR 372

Query: 419 LYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPER 478
           LYPPVP + R +++EI L  NG  +PAGT   I  + LHRR D++ +P  FDPD FLP  
Sbjct: 373 LYPPVPSMGRILSEEINL--NGYTVPAGTYCHIQIFDLHRREDLFKDPLVFDPDRFLPHN 430

Query: 479 SANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILK 538
           +  RH YA++PFSAGPR+C+G+K+A+L++K +LS +LR + +    K  D K   D++L+
Sbjct: 431 TEGRHPYAYIPFSAGPRNCIGQKFAILEMKSLLSAVLRRYNLYPITKPEDLKFVLDLVLR 490

Query: 539 RAEGFQVRLQPRKRM 553
             E   VR   R ++
Sbjct: 491 TTEPVHVRFVKRNKV 505


>UniRef50_Q964T1 Cluster: Cytochrome P450 4c21; n=1; Blattella
           germanica|Rep: Cytochrome P450 4c21 - Blattella
           germanica (German cockroach)
          Length = 501

 Score =  309 bits (758), Expect = 1e-82
 Identities = 171/468 (36%), Positives = 256/468 (54%), Gaps = 37/468 (7%)

Query: 85  HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144
           ++ ++  + G R  V +  P  +EV+L +   IDKA  Y  F  WLG GLL S+G KW  
Sbjct: 68  YKPLILWYFGNRPFVNISSPELIEVVLRNTQLIDKAFLYDLFHSWLGTGLLTSSGAKWHQ 127

Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAM 202
           HRK+I PTFH ++L+ FI +F   S  +V KL+KE     F    Y+S C ++I+ ETAM
Sbjct: 128 HRKIITPTFHFSILEGFITIFAEKSEILVRKLQKEVGRGPFFIRQYVSNCALDIICETAM 187

Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262
           G S + QD+   EY  A+ KM D+L  R     L P+ +FK T Y     K L +++G  
Sbjct: 188 GTSVNAQDEGFSEYVTAINKMTDVLSDRMANPLLYPEFIFKLTPYYWTHKKCLKVLNGFV 247

Query: 263 KKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQ 322
            K+I+ +KEE    +K S + +T+             E    G+   +            
Sbjct: 248 NKIIQERKEE----RKKSKVTQTS-------------EDADIGKKKRVPFLDTLLDASED 290

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
             +L   D+L E                V T MFEGHDT +A  ++ L  +G H +IQ++
Sbjct: 291 DNKLTDTDILEE----------------VHTFMFEGHDTVSAAMTWLLFELGHHPEIQEE 334

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
             +E+  IF  SDR  T  D   M YLER + E+LRL+P V    R+ +Q+  L   G  
Sbjct: 335 AYKEVQDIFQGSDRVPTMADLNNMNYLERVIKESLRLHPSVIYFVREAHQDFEL--GGYT 392

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           IPAGT +  +   +HR P+++PNP  F+PDNFLP+R  NRH YA++PFSAGPR+C+G+++
Sbjct: 393 IPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVNRHPYAYIPFSAGPRNCIGQRF 452

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           A+L+ KV+LS +LR++R  +  K  D K + ++I    +  Q+ ++ R
Sbjct: 453 ALLEEKVVLSYLLRHYRFRTVNKREDSKFKLEMINTPVKPIQLIIEAR 500


>UniRef50_Q6VAB7 Cluster: Cytochrome P450 CYP4AB2; n=6;
           Apocrita|Rep: Cytochrome P450 CYP4AB2 - Solenopsis
           invicta (Red imported fire ant)
          Length = 511

 Score =  308 bits (755), Expect = 3e-82
 Identities = 169/458 (36%), Positives = 264/458 (57%), Gaps = 36/458 (7%)

Query: 98  LVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNV 157
           LVF+  P D+E+IL++  +I K+  Y   +PWLG GLL S G KW   RK++ PTFH N+
Sbjct: 78  LVFIRHPDDLEIILNNTKHISKSNLYDALRPWLGMGLLTSGGSKWHLRRKILTPTFHFNI 137

Query: 158 LKSFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMGVSKSTQDQSGFE 215
           L+ F+++      ++   LK        D   ++SE T+  + ETAMG S         +
Sbjct: 138 LQQFVEILIEEGESMTRSLKNAGGTITKDLVPFISEYTLNAICETAMGTSLQEMGSFQQQ 197

Query: 216 YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKE--EF 273
           Y  AV +M ++L  R  + WL+ D +F  T   + Q KLL I+HG T+KVI ++K+  + 
Sbjct: 198 YRKAVHRMGELLVYRAMRPWLKYDWIFSLTSKGREQKKLLKILHGFTEKVIAKRKDYHKR 257

Query: 274 ASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLL 333
             G+   NLN+    +E  T               G+K           KKR A LDLL+
Sbjct: 258 TKGQYLKNLNKDVVPNETET--------------IGIK-----------KKRFAMLDLLI 292

Query: 334 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 393
           ++SQ G+ ++D +I+E+VDT MFEG DTT     F LS++  H+DIQD V +E+D +  +
Sbjct: 293 QASQEGL-LTDFDIREEVDTFMFEGFDTTGMAMCFILSLLAEHKDIQDCVRKEIDAVMQE 351

Query: 394 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIAT 453
           +   +  +   +++YLERC+ E LRLYP V  I+R  ++E  L +    IPAGT +++  
Sbjct: 352 NQGKLNMKSLQDLQYLERCIKEALRLYPSVYFISRITSEETELKT--YLIPAGTLVILNF 409

Query: 454 YKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILST 513
           Y  HR  + +PNP  FDPD FLP+   NRH Y+++PFSAGPR+C+G+++A+L+LK +L  
Sbjct: 410 YITHRDSNFWPNPEVFDPDRFLPDNIRNRHPYSYLPFSAGPRNCIGQRFALLELKAMLVP 469

Query: 514 ILRNFRV--ISDLKESDFKLQADIILKRAEGFQVRLQP 549
           ++ NF +  +  L+   F +  D+IL+  +  +++  P
Sbjct: 470 LIYNFYLEPVDYLENQRFGI--DMILRSLDPCRLKFVP 505


>UniRef50_Q27589 Cluster: Cytochrome P450 4d2; n=8;
           Acalyptratae|Rep: Cytochrome P450 4d2 - Drosophila
           melanogaster (Fruit fly)
          Length = 501

 Score =  306 bits (752), Expect = 8e-82
 Identities = 173/496 (34%), Positives = 280/496 (56%), Gaps = 43/496 (8%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120
           N L + G   +   + V+K+    +  + ++WI  +L VF  DPRD+E +LSS  +I K 
Sbjct: 42  NLLMYRGLDPEQIMDFVKKN-QRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKN 100

Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180
             Y+    WLG+GLL+STG+KW   RK+I PTFH  +L+ F+++F+  S  +V++L+  A
Sbjct: 101 NLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRA 160

Query: 181 SN---FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLR 237
                 +    +    ++I+ ETAMG   + Q      Y  AV  + +IL  R    W R
Sbjct: 161 DGKTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQR 220

Query: 238 PDLLFKFTD--YAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGK 295
            D +F+ T    AK Q K + ++H  T+ +I+ ++E   +       N   TT E     
Sbjct: 221 VDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVN-------NSKETTPE----- 268

Query: 296 LTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIM 355
               E ++F                GQK+R+A LD+LL+S+  G  +SDE+I+E+VDT M
Sbjct: 269 ----EEVNF---------------LGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFM 309

Query: 356 FEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLM 414
           FEGHDTT +  SF L  +  H ++Q ++ +E+  + G D   PVT +D  E+K++E  + 
Sbjct: 310 FEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIK 369

Query: 415 ETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNF 474
           E+LRL+PPVP+I R   +++ +   GK IPAGT   +  + L R P+ + +P++F P+ F
Sbjct: 370 ESLRLHPPVPMIGRWFAEDVEI--RGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERF 427

Query: 475 LPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 534
             +     H YA++PFSAGPR+C+G+K+AML++K  +S +LR+F ++    E    +  +
Sbjct: 428 DAD-VPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSM--N 484

Query: 535 IILKRAEGFQVRLQPR 550
           I+L+ A G  + L+PR
Sbjct: 485 IVLRSANGVHLGLKPR 500


>UniRef50_UPI00015B5D09 Cluster: PREDICTED: similar to cytochrome
           P450 CYP4AB2; n=4; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis
          Length = 519

 Score =  300 bits (737), Expect = 5e-80
 Identities = 157/472 (33%), Positives = 264/472 (55%), Gaps = 24/472 (5%)

Query: 82  DYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQK 141
           D  +  + KIW   + ++ +  P DVE +L+S  +I+K+  Y    PW G GLL STG K
Sbjct: 62  DKQYYPIYKIWTTHKAVIVILHPDDVETLLTSMEHIEKSIMYDMVHPWFGTGLLTSTGAK 121

Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD-CHDYMSECTVEILLET 200
           W+  RK++ P FH +VL+ + D+   N+  V+  LK   S  +   + ++  T++++ ET
Sbjct: 122 WQKRRKILTPAFHFHVLQKYFDIIVENNEKVMHSLKSNGSVINNLVELLTYYTLDVICET 181

Query: 201 AMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHG 260
           AMG +   ++    +Y   +  + + +  R  + W + D  F++T  A+ Q K L++IHG
Sbjct: 182 AMGTTLLDKEHQQ-KYRNVLHDVSNAVIYRLMRPWFQVDWTFRWTSVAEKQKKALEVIHG 240

Query: 261 LTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXX 320
            +KK+IK +KE +    K   LN+    S+ S  K    E   +                
Sbjct: 241 FSKKIIKERKE-YHEKTKGHYLNQLE--SDQSDDKKEDEEYFGY---------------- 281

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
            +KKRLA LDLL+   + G  I D  I+E+VDT +FEGHDT+A    F + ++  H D+Q
Sbjct: 282 -RKKRLAMLDLLIAKQKDGNQIDDAGIREEVDTFIFEGHDTSAMAMCFAILLIAEHNDVQ 340

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           D++  E+ ++   S+  +   +  ++ YLE C+ E+LRLYP VP I+R V +++ L    
Sbjct: 341 DRIRAEVKEVLEKSEGKMGVPEIQQLNYLELCIKESLRLYPSVPFISRGVTKDLHL--KN 398

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             +P GT + I  + LHR P+ +P+P KFDPD FLP+R   RH Y+++PFSAGPR+C+G+
Sbjct: 399 YIVPKGTLIQINIFSLHRDPNFWPDPEKFDPDRFLPDRFQGRHPYSYIPFSAGPRNCIGQ 458

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552
           K+AM++LK  ++ ++  F +       +  +  D++L+ A   ++    R++
Sbjct: 459 KFAMMELKAFIAHLISEFYLEPIDLAHEVLITPDLVLRPARPVKLLFNERQQ 510


>UniRef50_Q9Y1T8 Cluster: Cytochrome P450 4W1; n=3; Arthropoda|Rep:
           Cytochrome P450 4W1 - Boophilus microplus (Cattle tick)
          Length = 549

 Score =  299 bits (734), Expect = 1e-79
 Identities = 169/489 (34%), Positives = 267/489 (54%), Gaps = 37/489 (7%)

Query: 69  SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP 128
           S  +F+     S  Y +  + + +     ++ L+    VE +L+S+  + K  EY   KP
Sbjct: 85  STHLFQVAFGFSRIYKNHGMFRFYDATHPVLVLFKAEAVEELLTSNTVLKKGHEYELIKP 144

Query: 129 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCH-- 186
           WLG GLL S+G KWRS RKL+ P FH  +L+ F+   N  S  +V KL +   +  C+  
Sbjct: 145 WLGTGLLTSSGSKWRSRRKLLTPAFHFRILEDFLPAVNDQSNILVRKLGQLGKDRSCNIV 204

Query: 187 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLR-HTKI-WLRPDLLFKF 244
             ++ C ++I+ ET MG + + Q     EY  A+  +      R  T + W+  D +F+ 
Sbjct: 205 PLVTLCALDIICETIMGYTINAQSNQDSEYVQAIKVLGHSFTRRLETPLYWI--DAIFQL 262

Query: 245 TDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKK-PSNLNETATTSEPSTGKLTSVEGLS 303
           +   +   + +  +H  T KVI+ +K E  S  +   +  ETA+ S+             
Sbjct: 263 SKPGREFARKVKELHQFTLKVIRERKREILSCPELQESYEETASESDVY----------- 311

Query: 304 FGQSSGLKXXXXXXXXXGQKKRLAFLDLLL-ESSQSGVAISDEEIKEQVDTIMFEGHDTT 362
                GLK             R  FLD+LL E  +     ++E ++E+VDT MFEGHDTT
Sbjct: 312 -----GLKGTA----------RKPFLDILLREHIKDPENFTEEHVREEVDTFMFEGHDTT 356

Query: 363 AAGSSFFLSMMGIHQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYP 421
           A G S+ + ++ +H + QD + +ELD IFG D  RPVT +D  +MKY+E CL E+ RLYP
Sbjct: 357 AMGMSWAIYLIALHTEHQDLIHQELDTIFGSDKTRPVTSEDLKQMKYMECCLKESQRLYP 416

Query: 422 PVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSAN 481
            VP I+R+  ++  +   G+K+P GT + +A Y LH    V+P P++F PD F PE    
Sbjct: 417 SVPFISRKCEEDAVIC--GRKVPKGTDIQVAIYNLHHDEQVFPKPDEFRPDRFFPENVRG 474

Query: 482 RHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAE 541
           RH +AFVPFSAGPR+C+G+++AM++ KV+++ ILRN+++++        + A+++L+   
Sbjct: 475 RHAFAFVPFSAGPRNCIGQRFAMMEEKVVIANILRNYKLVALHYRDKIHVMAELVLRPTS 534

Query: 542 GFQVRLQPR 550
           G  V   PR
Sbjct: 535 GLHVIFIPR 543


>UniRef50_UPI00015B569D Cluster: PREDICTED: similar to cytochrome
           P450 CYP4C39; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4C39 - Nasonia vitripennis
          Length = 510

 Score =  277 bits (680), Expect = 4e-73
 Identities = 170/470 (36%), Positives = 257/470 (54%), Gaps = 40/470 (8%)

Query: 87  SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146
           +V  +W+G +  V +  P  +EV+L+S V I K+  Y    PWLG+GLL  TG+KW  HR
Sbjct: 72  NVYIMWLGMQPYVNIQKPHHMEVLLTSTVNIKKSSIYNIIIPWLGDGLLTLTGKKWHHHR 131

Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN-----FDCHDYMSECTVEILLETA 201
           +L+ P FH  VL+ F +  +  +    + LK++ S+      D   + S  T++++ +TA
Sbjct: 132 RLLTPAFHFRVLEQFTETMHEKADVFNECLKEQVSSNPKEPVDIFSFASRFTLDVICKTA 191

Query: 202 MGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261
           MG+    Q  S   Y  +V +M   +  R+    LRP   +  +D+  ++T+      G 
Sbjct: 192 MGIDMDAQRGSMNLYTKSVNQMSRFVVNRY----LRP---WYASDFIYSKTE-----DGK 239

Query: 262 TKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXG 321
             +       E++S      L+E          KL S +        G+K          
Sbjct: 240 QSQAAISVMREYSSKVIKERLDERR--------KLKSSKDEDKEDEFGIK---------- 281

Query: 322 QKKRLAFLDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
            ++  AFLDLLLE+S++    +S++E++ +VDT MF GHDTTA   SF L ++G H DIQ
Sbjct: 282 -QRNKAFLDLLLEASENDKNPLSNDELRNEVDTFMFAGHDTTATAISFTLLLLGNHLDIQ 340

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
            KV EEL  +F  D D+P    D  ++KYL+R + ETLRLYP  P   R + ++     +
Sbjct: 341 KKVHEELQTVFNNDVDKPTRAADLSQLKYLDRVIKETLRLYPSAPSFLRTLVEDTIF--D 398

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G  I  G+ ++I  Y +HR P V+ NP  FDPD FLPE   +RH YA++PFSAGPR+C+G
Sbjct: 399 GHTICKGSVIIINAYDMHRDPKVWENPTVFDPDRFLPENVRSRHPYAYIPFSAGPRNCIG 458

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549
           +K+AML+LK+ L+ ILR +RV SD    + KL   IIL+  +  +V   P
Sbjct: 459 QKFAMLELKIALTAILRKWRVKSDTLPENLKLLHSIILRCNKPIKVYFTP 508


>UniRef50_Q9NB96 Cluster: P450 CYP319A1; n=2; Parasitiformes|Rep:
           P450 CYP319A1 - Boophilus microplus (Cattle tick)
          Length = 531

 Score =  275 bits (674), Expect = 2e-72
 Identities = 155/474 (32%), Positives = 245/474 (51%), Gaps = 28/474 (5%)

Query: 83  YDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKW 142
           Y  E     ++G R  + +Y    VEV L++     K+  Y     WL  GLL S G KW
Sbjct: 80  YQKEGFFAFYLGTRPCITIYKAEHVEVFLNNRHTQSKSIHYELLHSWLRTGLLTSAGPKW 139

Query: 143 RSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLET 200
           +S R+++ P FH  +L+ F+   N  +R    ++         D     + C +++LLET
Sbjct: 140 KSRRRMLTPAFHFKILEDFVAPMNKMARLTAARITDRIKEPWIDVVPMAAACALDVLLET 199

Query: 201 AMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHG 260
            MGV+ +        Y   V  + + +  R    WL  D L+  T+  +   K +  IH 
Sbjct: 200 IMGVTNTNDGGESQRYVKNVNSVAERMVRRSQAPWLVLDCLYYRTEDGRQYQKNVSAIHA 259

Query: 261 LTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXX 320
            T KVI +++EE  +    +N  +  T        LT   G +F                
Sbjct: 260 FTTKVISKRREEIINEIHAANSKKDNTPKMDEDFHLT---GRTF---------------- 300

Query: 321 GQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
              KRL F+D+LL  S +    ++ ++I+E+VDT MFEGHDTTA G ++ L M+  H  +
Sbjct: 301 ---KRLTFIDILLRYSIEVDSTLTTDDIREEVDTFMFEGHDTTAMGIAWSLYMIASHHHV 357

Query: 380 QDKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438
           Q K+ +ELD +   D D  +T +   E+KY +R L E  RL+P VP+I R  +++I+L  
Sbjct: 358 QAKIHKELDSVLQSDLDADITLEKIKELKYFDRVLKECQRLFPSVPVIGRATSEDISLGK 417

Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
           +   +PA + + I  Y LHR    +P+P  FDPD FLPE   +   YA+VPFSAGPR+C+
Sbjct: 418 H--VVPADSDVDIFIYALHRDQVCFPDPEVFDPDRFLPENVVHPAPYAYVPFSAGPRNCI 475

Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552
           G++YA++++K+I++TILR F + +  +     L  +++L+   G +V   PR R
Sbjct: 476 GQRYALMEVKIIVATILRRFTLEAVDQRDQLMLACELVLRPLNGLKVSFTPRSR 529


>UniRef50_UPI00015B604A Cluster: PREDICTED: similar to cytochrome
           P450 CYP4AB2; n=8; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis
          Length = 519

 Score =  271 bits (665), Expect = 3e-71
 Identities = 164/505 (32%), Positives = 261/505 (51%), Gaps = 29/505 (5%)

Query: 40  RRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLV 99
           + R  EL DK+          N L F         N++ +  + ++  + K W+GP   V
Sbjct: 28  KSRSKELLDKIPGPPTVPILGNLLMFNVPIGKKTWNVI-RDLNKNYYPIAKFWLGPYPYV 86

Query: 100 FLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLK 159
            ++ P D+E++LSS  +++K   Y    PWL  GLL S+G KW+  RK++ P FH  +L+
Sbjct: 87  SIHHPDDLEILLSSTKHLEKGSAYTVLHPWLRTGLLTSSGSKWQQRRKILTPAFHFKILR 146

Query: 160 SFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMGVSKSTQDQS-GFEY 216
            ++D+ N + +  ++ L+ E S        + S  T+ I+ ETAMG++    D     EY
Sbjct: 147 KYMDITNEHGKKFIEALRTENSETVQSLMPFCSNYTLHIICETAMGIALDKIDTKISKEY 206

Query: 217 AMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASG 276
             AV    DI +L   ++ +RP        Y K    L     G  +    R   +F   
Sbjct: 207 KNAV---ADIANLIMYRV-MRP--------YLKEWMMLPVWTFGRLQTQTLRTLHKFT-- 252

Query: 277 KKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESS 336
                  +T  T      K +  + L  G               G KK+LA LDLLL ++
Sbjct: 253 -------KTVLTERREYHKRSDNKYLK-GFHDDTYDVNKDDVAIGGKKKLAMLDLLLSAA 304

Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396
           Q G+   DE IKE+VDT MF GHDTT     + + ++  H++IQ+K   E+ ++  +S+ 
Sbjct: 305 QDGLT-DDEGIKEEVDTFMFAGHDTTGIALVYAIMLLAEHKEIQEKARAEVIEVLTESNG 363

Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456
            +   +  ++ YLERC+ E+LR++PPV  ++R V ++I L +    +PAGT +    + L
Sbjct: 364 EIGTLEIQKLHYLERCIKESLRIFPPVSALSRTVKEDIQLKNY--VVPAGTEIGCHIFDL 421

Query: 457 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 516
           HR P+ +P P K+DPD FLPE    RH YA++PFSAG R+C+G+K+AM++LK + + IL 
Sbjct: 422 HRDPNFWPEPEKYDPDRFLPENIQGRHPYAYIPFSAGSRNCIGQKFAMMELKSLTARILY 481

Query: 517 NFRVISDLKESDFKLQADIILKRAE 541
           NF +    +  D KL  D++ +  E
Sbjct: 482 NFELEPVSQTKDMKLTLDLVTRPLE 506


>UniRef50_Q9VA27 Cluster: Cytochrome P450 4c3; n=15; Coelomata|Rep:
           Cytochrome P450 4c3 - Drosophila melanogaster (Fruit
           fly)
          Length = 535

 Score =  262 bits (643), Expect = 1e-68
 Identities = 112/231 (48%), Positives = 175/231 (75%), Gaps = 3/231 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G+KKRLAFLDLL+++S+ G  +S+E+I+E+VDT MFEGHDTT+A  S+ L ++G H + Q
Sbjct: 306 GKKKRLAFLDLLIDASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQ 365

Query: 381 DKVIEELDQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           ++V+EELD IFGD  + P T ++ ++M+YLE C+ ++LRL+P VP++AR V +++ +   
Sbjct: 366 ERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNI--G 423

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           GK +PAGT  +I TY LHR P V+P P +F+PDNFLPE  A RH +A++PFSAGPR+C+G
Sbjct: 424 GKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIG 483

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +K+A+L+ K ++ST+LR +++ +  +  D  L  ++IL+  +G +V++ PR
Sbjct: 484 QKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVKITPR 534



 Score =  163 bits (396), Expect = 1e-38
 Identities = 87/277 (31%), Positives = 141/277 (50%), Gaps = 4/277 (1%)

Query: 23  VLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSAD 82
           V L+ +++++   +   R RL +  +K+          NA+E      ++F  ++     
Sbjct: 31  VFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVIGMQKL 90

Query: 83  YDHE-SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQK 141
           +     + ++W G    V L++P  VE IL+S  +++K+ +Y +  PWLG GLL ST +K
Sbjct: 91  WGTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRK 150

Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLE 199
           W S RK++ P FH  +L  FID+FN  S  +  KL  E  +  F+   Y++ CT++I+ E
Sbjct: 151 WHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNLFPYVTLCTLDIVCE 210

Query: 200 TAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 259
           TAMG     Q  S  EY  AV  +  I+  R  KIWL+ D +F  T   K     ++ +H
Sbjct: 211 TAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLH 270

Query: 260 GLTKKVIKRKKEEFA-SGKKPSNLNETATTSEPSTGK 295
           G +  VI+ +K E A   +  +N N  A  +    GK
Sbjct: 271 GFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGK 307


>UniRef50_O45120 Cluster: Family 4 cytochrome P450; n=2; Coptotermes
           acinaciformis|Rep: Family 4 cytochrome P450 -
           Coptotermes acinaciformis
          Length = 501

 Score =  253 bits (619), Expect = 1e-65
 Identities = 116/230 (50%), Positives = 161/230 (70%), Gaps = 2/230 (0%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G K+R AFLDL+L++SQ G +++DEEI+E+VDT MFEGHDTT +  SF +  +  +QD+Q
Sbjct: 274 GLKRRHAFLDLMLQASQDGASLTDEEIREEVDTFMFEGHDTTTSALSFTMWCLAKYQDVQ 333

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           +K + EL QIFGDS R  TF+D  EMKYLE+ + ETLRLYP V    RQ+ +  T+    
Sbjct: 334 EKAVVELKQIFGDSTRDATFRDLQEMKYLEQVIKETLRLYPSVNCFGRQLTENFTVGDYV 393

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
              PAG  + I  Y LHRRP+ +P+P +FDPD FLPE    RH Y +VPFSAGPR+C+G+
Sbjct: 394 N--PAGANVWIYPYHLHRRPEYFPDPERFDPDRFLPENCVGRHPYCYVPFSAGPRNCIGQ 451

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           K+A+L+LK  +S +LR+F+VI      + + + D +L+ A G +V+LQPR
Sbjct: 452 KFAILELKSTISQVLRSFKVIESDCNGNIRYKLDFVLRSASGLKVKLQPR 501



 Score =  136 bits (330), Expect = 1e-30
 Identities = 79/234 (33%), Positives = 122/234 (52%), Gaps = 4/234 (1%)

Query: 41  RRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVF 100
           R   +LADK+          N L+F G   D +R +V+    Y H ++V++W G  L+V 
Sbjct: 25  RSRMQLADKIPGPKALPVLGNLLDF-GLRPDRYRELVE-GLIYKHGTIVRLWSGAYLIVI 82

Query: 101 LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKS 160
           L + + VE +LSS   IDKA  YRF  PWLG+GLL STGQ   +  +    +F L   + 
Sbjct: 83  LTEAKYVEALLSSTSQIDKAYTYRFVWPWLGSGLLTSTGQALGNPPQAADSSFPLQGTRE 142

Query: 161 FIDLFNANSRAVVDKLKKEAS--NFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAM 218
           F        + +V+K  +  +   FD   YM+ C ++ + ET+MGV+ + Q  S  EY  
Sbjct: 143 FRGCVQQKWKILVEKFSRHVNGPEFDVTPYMTLCALDNMSETSMGVTLNAQKDSDSEYVR 202

Query: 219 AVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272
           A+  + +I+  R  K W   D  F+ +   + Q K L I+H  T+ VI+ +K+E
Sbjct: 203 AIHSLGEIVFTRSGKPWYHSDTTFRLSTLGREQQKNLAILHSFTRSVIRSRKQE 256


>UniRef50_Q9VVN6 Cluster: Probable cytochrome P450 312a1; n=2;
           Sophophora|Rep: Probable cytochrome P450 312a1 -
           Drosophila melanogaster (Fruit fly)
          Length = 510

 Score =  242 bits (592), Expect = 2e-62
 Identities = 145/469 (30%), Positives = 249/469 (53%), Gaps = 38/469 (8%)

Query: 74  RNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNG 133
           R   +   ++ H+   K+W+G +L +   +P+D++ + S+   + K  +YR F+ WL  G
Sbjct: 59  RRATEMINEHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEG 118

Query: 134 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMS--E 191
           L  S  +KW   RK++ P F+  ++K F+ +F   SR ++  + K A + D  D++    
Sbjct: 119 LFTSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLIS 178

Query: 192 C-TVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 250
           C T++ + ETA+GVS  +Q  +  EY  AV  +  I+  R   I+ R   +FK T + K 
Sbjct: 179 CFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKR 238

Query: 251 QTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGL 310
           + +L+  +HG T+ +I+         K+   +N+ A             E  ++ QSS  
Sbjct: 239 EQELIKTLHGFTEGIIQ---------KRIDEINQDA-------------ENRNY-QSSDA 275

Query: 311 KXXXXXXXXXGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFF 369
           +         G K+ L FLD LLL     G  ++ ++I+E+VDTI+F G D TA   +FF
Sbjct: 276 ELD-------GVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFF 328

Query: 370 LSMMGIHQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIAR 428
           +  M +H + Q +  EE+  + G D   P++ +   ++++LE C+ ETLR+YP  P+ AR
Sbjct: 329 MYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTAR 388

Query: 429 QVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFV 488
           +     T+  N   IP G+ ++I+   + R  D +P+P  F PD +            F+
Sbjct: 389 KATANCTI--NDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFI 446

Query: 489 PFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIIL 537
           PF AG RSC+G++YAM+ LK++L+ +LRNF +   L E   KL+ + ++
Sbjct: 447 PFMAGARSCMGQRYAMVMLKMVLAHLLRNF-LFEPLGERQVKLKLNFVI 494


>UniRef50_UPI00015B5014 Cluster: PREDICTED: similar to cytochrome
           P450 CYP4AB2; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis
          Length = 604

 Score =  239 bits (586), Expect = 1e-61
 Identities = 138/465 (29%), Positives = 238/465 (51%), Gaps = 21/465 (4%)

Query: 88  VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 147
           + K W     L+ +  P D+EVILSS     K   Y++ + WL +GLL + G  +R+ R+
Sbjct: 148 ICKGWAMGLPLLSVRHPDDLEVILSSQKACYKEFPYKYLRSWLNDGLLTNKGDTYRARRR 207

Query: 148 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMGVS 205
           ++ P FH N+L+ ++D+ N  S  ++ +L+     F  D     ++ ++ I++E+AMG+ 
Sbjct: 208 MLTPAFHFNMLRRYVDIMNEQSGRLMTELRANGKEFVLDVLPIYADVSLNIIIESAMGID 267

Query: 206 KSTQDQSGF-EYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264
               D+    +Y  A+  M  +L  R  + ++   ++  FT+  + Q   L ++   T K
Sbjct: 268 LDKTDKKVIKDYKEAIEDMGIVLTYRMLRPYILDWMMTPFTEIGRKQIHALKVLREFTDK 327

Query: 265 VIK--RKKEEFASGKKP-SNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXG 321
           +IK  RK  E   G K      ++    + S      ++ +                  G
Sbjct: 328 IIKERRKYHEMLGGIKGYKEFTDSLENQDESESIYVKIQLM------------IHHFFTG 375

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
            KK+L  LD+LL + + G+ + ++ IKE+VDT +  G DTT    ++F  +M  ++  QD
Sbjct: 376 HKKKLPMLDILLSAEKDGL-LDEKGIKEEVDTFLLGGTDTTRMVMAYFTMLMAENKKCQD 434

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           K   E+ ++   S       +  +M YLE+C+ E++RLYP    I R    +I L +   
Sbjct: 435 KARAEVCKVLERSGGKRGMTELSQMPYLEQCIKESMRLYPIASTIFRHTVDDIQLKNY-- 492

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            IPAG  ++      HR P+ +  P KFDPD FLPE   +RH +A++PFSAGPR+C+G+K
Sbjct: 493 TIPAGVVVICQIIDAHRDPNFWTEPEKFDPDRFLPENCRHRHPFAYLPFSAGPRNCIGQK 552

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVR 546
           +  +++K + S +L NF +       D +L  D +L+ A+ F  +
Sbjct: 553 FGWMEVKAVCSRLLYNFYLEPIDSTRDMQLIGDFVLRPADPFHTK 597


>UniRef50_UPI0000D566B3 Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 511

 Score =  237 bits (580), Expect = 6e-61
 Identities = 107/233 (45%), Positives = 168/233 (72%), Gaps = 1/233 (0%)

Query: 321 GQKKRLAFLDLLLESSQSGVA-ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           G+KKRLAFLDLLLE++++    ++DE+I+E+VDT MF GHDT+     + L  +  + + 
Sbjct: 279 GKKKRLAFLDLLLEANKNSEGGLTDEDIREEVDTFMFAGHDTSTVTVGWTLFTLSNYPEY 338

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q+KV +ELD+IF   +RP+T QD L+M+YL++ + ET RL P VP+IAR ++Q++ + ++
Sbjct: 339 QEKVHQELDEIFQGEERPITPQDVLKMQYLDKVIKETQRLIPVVPVIARTLDQDLEIVAS 398

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
            + IPAG  +VI   +LH+ PD +P P++FDP+ FLPE  + RH Y+FVPFSAGPR+C+G
Sbjct: 399 SRTIPAGVMVVIHLARLHKDPDQFPEPDRFDPERFLPENVSKRHPYSFVPFSAGPRNCLG 458

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552
           +K+A+   KV+L++ILR ++V ++ K  + K   +I+L+   G  V L+PR+R
Sbjct: 459 QKFALRNTKVLLASILRKYKVRAEKKIDEMKYNIEIVLRPQGGLSVALEPRRR 511



 Score =  144 bits (348), Expect = 7e-33
 Identities = 77/248 (31%), Positives = 130/248 (52%), Gaps = 4/248 (1%)

Query: 33  YAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIW 92
           +  W   R+R+++  + +            LE +      F + V  + +  +    + W
Sbjct: 19  FCKWLKDRKRIWDAIEPIGGEKWYPLIGTCLELIKTKRKDFYD-VYCARNMKYGPFFRTW 77

Query: 93  IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLI-STGQKWRSHRKLIAP 151
           +G    V +  P  VE ILSS V + K + YRF  PWLG GL+  S  +KWR HRKLI P
Sbjct: 78  MGFIPAVHVMKPDHVERILSSTVNLTKGDNYRFVVPWLGEGLITGSNHKKWRVHRKLITP 137

Query: 152 TFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAMGVSKSTQ 209
           TFH ++L + +++     + + ++L  +A+   F+ + +++ C ++I+ ETAMGV  +  
Sbjct: 138 TFHFSILDNMMEVMAEKGQFLAEQLVPKANGQFFNIYPFLTLCELDIICETAMGVEVNAM 197

Query: 210 DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRK 269
             S  EY  +V  + DI+  R    +L PD +F  +   +   K L I+HG T+KVI+ +
Sbjct: 198 KHSQSEYVRSVYGISDIMLYRMFHPYLHPDFVFNLSSKGRQHKKYLSILHGFTRKVIQER 257

Query: 270 KEEFASGK 277
           KE+  SG+
Sbjct: 258 KEKLTSGR 265


>UniRef50_Q6ZWL3 Cluster: Cytochrome P450 4V2; n=83; Coelomata|Rep:
           Cytochrome P450 4V2 - Homo sapiens (Human)
          Length = 525

 Score =  226 bits (553), Expect = 1e-57
 Identities = 107/230 (46%), Positives = 157/230 (68%), Gaps = 3/230 (1%)

Query: 322 QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           + KR AFLDLLL  +   G  +S E+I+E+VDT MFEGHDTTAA  ++ L ++G + ++Q
Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
            KV  ELD +FG SDRP T +D  +++YLE  + ETLRL+P VP+ AR V+++  +   G
Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
            ++  GT  VI  Y LHR P  +PNP +F P+ F PE +  RH YA+VPFSAGPR+C+G+
Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           K+A+++ K ILS ILR+F + S+ K  +  L+  +IL+ + G  ++L+ R
Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520



 Score =  167 bits (405), Expect = 9e-40
 Identities = 79/204 (38%), Positives = 120/204 (58%), Gaps = 2/204 (0%)

Query: 71  DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 130
           + F+ I++ + +Y H  ++K+W+GP  +V LY+  +VEVIL+S   IDK+  Y+F +PWL
Sbjct: 72  EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131

Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 188
           G GLL STG KWRS RK++ PTFH  +L+ F+D+ N  +  +V KL+K  +   F+C  Y
Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191

Query: 189 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYA 248
           ++ C ++I+ ETAMG +   Q     EY  AV +M +++  R    WL  DL +      
Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEG 251

Query: 249 KNQTKLLDIIHGLTKKVIKRKKEE 272
               K L I+H  T  VI  +  E
Sbjct: 252 WEHKKSLKILHTFTNSVIAERANE 275


>UniRef50_UPI0000E46807 Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily v; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to cytochrome P450,
           family 4, subfamily v - Strongylocentrotus purpuratus
          Length = 487

 Score =  226 bits (552), Expect = 1e-57
 Identities = 106/231 (45%), Positives = 159/231 (68%), Gaps = 2/231 (0%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G K+R+AFLDLLL+  +   + +  +I+E+VDT MFEGHDTTAA +S+ + ++G H  +Q
Sbjct: 218 GSKRRIAFLDLLLKMQRDDPSFTKSDIREEVDTFMFEGHDTTAALASWAMFLIGHHTRVQ 277

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
            K+ +ELD +FGDSDRPVT  D  ++ YL   L ETLR++P VPI+ R + ++  +  +G
Sbjct: 278 KKLHQELDSVFGDSDRPVTADDLQKLPYLTCVLKETLRIFPSVPIVGRDLQEDCII--DG 335

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
           K  P GT L+IA   LHR P  +P P  FDPD FLPE S+ RH +++VPFSAGPR+C+G+
Sbjct: 336 KLAPRGTLLIIAIGSLHRDPTQFPEPLMFDPDRFLPEFSSKRHPFSYVPFSAGPRNCIGQ 395

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           ++A+++ KV+L+ +LR F + S     D    A++IL+ +EG  +++  RK
Sbjct: 396 RFALMEDKVLLANVLRCFSLESTQSLKDTMPIAELILRPSEGIHMKITRRK 446



 Score =  100 bits (239), Expect = 1e-19
 Identities = 60/168 (35%), Positives = 88/168 (52%), Gaps = 11/168 (6%)

Query: 98  LVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNV 157
           L F  DP ++   +SS V     EEYR     L   + + TG+KW   RK++ PTFH  +
Sbjct: 48  LQFKQDPNELVEQVSSWV-----EEYRTKSKGL---MRLCTGKKWFHRRKMLTPTFHFAI 99

Query: 158 LKSFIDLFNANSRAVVDKLKKEASNFDCHDY---MSECTVEILLETAMGVSKSTQDQSGF 214
           L +FI++F+  S  +  K  + A   D  +    ++ C ++I+ ETAMG     QD+S  
Sbjct: 100 LHNFIEVFDEQSNTLCQKFGEHAQKQDLVNICPLVTLCVLDIISETAMGKQLHAQDESNN 159

Query: 215 EYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262
           +Y  AVM+M DI+  R  K W  PD LF  T   K   + L I+H +T
Sbjct: 160 DYVNAVMRMSDIIQQRQKKPWFWPDPLFDNTKSGKEHAQCLQILHKMT 207


>UniRef50_UPI00015B561A Cluster: PREDICTED: similar to cytochrome
           P450 CYP4AB2; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4AB2 - Nasonia vitripennis
          Length = 478

 Score =  225 bits (551), Expect = 2e-57
 Identities = 134/451 (29%), Positives = 231/451 (51%), Gaps = 31/451 (6%)

Query: 90  KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149
           +IW     +V   DP D+ ++L+    I K   Y +F      GL+ STG+KW+  RK++
Sbjct: 39  RIWFFTCAVVITQDPDDLRILLTDKTNITKGFVYEYFHLMAKTGLITSTGEKWQYRRKIL 98

Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMGVSKS 207
            P FH +++K ++ +        V  +K +            S+ T+ I+LE AMG+   
Sbjct: 99  TPAFHTHIIKKYMKITFEQGERFVKSIKAQGDETVQSLIPVCSDLTLSIILEAAMGIQFQ 158

Query: 208 TQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIK 267
           T      EY  A+      +  R T+ +++ D + ++    +     + ++   T K+I 
Sbjct: 159 TIGNKAEEYRKAIEHYFSSIAYRATRPYIK-DWMLRYFSEGRRILATVKVLREFTDKIID 217

Query: 268 RKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLA 327
            ++ E+    K  +  +     +    + T  EG                    +KKRLA
Sbjct: 218 ERR-EYHKQTKQESFQKYV--DDDMEHECTDGEG--------------------RKKRLA 254

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
            LDLLL + + G+ I +E IKE+VDT    G+DTT     + L +M  ++D Q+    E 
Sbjct: 255 MLDLLLMAEKEGL-IDEEGIKEEVDTFTAAGYDTTGMEMVYLLMLMAENKDQQELARAEA 313

Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447
           ++I   S   ++ ++  +M+Y+ERC+ E+LRL+P  P I R V ++I L +    +PAGT
Sbjct: 314 NRILDASGGKISMKEINQMEYIERCVKESLRLFPTAPHIVRAVTEDIQLKNY--MVPAGT 371

Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507
            + +  + LHR P  + +P KFDPD FLP  +  R+ + ++PFS GPR+C+G+K+A+ +L
Sbjct: 372 DIFVPIHILHRDPKYWSDPLKFDPDRFLPGEAEKRYPFTYLPFSHGPRNCIGQKFAIAEL 431

Query: 508 KVILSTILRNFRV--ISDLKESDFKLQADII 536
           K +L+ +LRNF +  +S  K+  F L   ++
Sbjct: 432 KSLLACVLRNFYLEPVSYTKDLQFTLHVVLL 462


>UniRef50_A0JMQ6 Cluster: Cytochrome P450, family 4, subfamily V,
           polypeptide 2; n=9; Coelomata|Rep: Cytochrome P450,
           family 4, subfamily V, polypeptide 2 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 513

 Score =  221 bits (541), Expect = 3e-56
 Identities = 98/232 (42%), Positives = 161/232 (69%), Gaps = 3/232 (1%)

Query: 321 GQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           G +KR AFLD+LL++  + G  ++ ++I+E+VDT MFEGHDTTAA  ++ + ++G H ++
Sbjct: 280 GMRKRRAFLDMLLKTKDEDGKMLTHKDIQEEVDTFMFEGHDTTAAAMNWAIHLLGSHPEV 339

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q K  +EL ++FG+S+RPV  +D  +++YLE  + E+LRL+P VP  AR +  +  +  N
Sbjct: 340 QRKAQQELFEVFGESERPVNTEDLKKLRYLECVIKESLRLFPSVPFFARTICDDTQI--N 397

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G K+P GT +V+ TY LHR P  +P+P +F P+ FLPE    RH YA++PFSAG R+C+G
Sbjct: 398 GFKVPKGTNIVVITYALHRDPRFFPDPEEFRPERFLPENCVGRHPYAYIPFSAGLRNCIG 457

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           +++A+++ KVIL+ ILR F +++  K  + +   +++L+  +G  + L+ RK
Sbjct: 458 QRFAIMEEKVILAYILRYFNIVACQKREELRPLGELVLRPEQGIWITLERRK 509



 Score =  169 bits (412), Expect = 1e-40
 Identities = 77/213 (36%), Positives = 123/213 (57%), Gaps = 3/213 (1%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120
           NAL+F   + D F  +V  + ++ +  ++KIWIGP   + L+    VE +L++ V+IDKA
Sbjct: 55  NALQFKS-NGDFFLQLVGYTTEFQNSPLLKIWIGPIPFLILFHAETVETVLNNPVHIDKA 113

Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180
             Y+F  PWLG GLL STG KWR  RK++ PTFH ++L  F+++ N  +  +++KL+K+A
Sbjct: 114 YAYQFLHPWLGTGLLTSTGDKWRRRRKMLTPTFHFSILTEFLEVMNEQAEVLIEKLEKQA 173

Query: 181 SN--FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRP 238
               F+C  +++ C ++I+ ETAMG     Q     EY   V +M DI+  R    W  P
Sbjct: 174 GKGPFNCFSHITLCALDIICETAMGKRIYAQSNYDSEYVRTVYRMSDIITRRQRMPWYWP 233

Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKE 271
           D ++ +    +   + L I+H  T+ VI  + E
Sbjct: 234 DFVYNYVGEGREHNRSLKILHSFTESVINERAE 266


>UniRef50_Q9NGQ5 Cluster: Insecticide resistance-associated
           cytochrome P450; n=2; Cucujiformia|Rep: Insecticide
           resistance-associated cytochrome P450 - Diabrotica
           virgifera virgifera (western corn rootworm)
          Length = 501

 Score =  219 bits (535), Expect = 2e-55
 Identities = 102/229 (44%), Positives = 149/229 (65%), Gaps = 2/229 (0%)

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           ++K+LAFLDLLL +  S   I D+ IK++V+T MFEGHDTTA G S+ L  +  H + QD
Sbjct: 273 KRKKLAFLDLLLNAKLSKGIIDDQGIKDEVNTFMFEGHDTTATGISWILRQLATHSEYQD 332

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           ++ EE+  + GD+ +     D  E+K +ER + ETLRL+PPVP IAR ++++I L  NG 
Sbjct: 333 QIYEEIITVLGDAQKQPDLNDLNELKVMERFIKETLRLFPPVPYIARTLDEDIEL--NGY 390

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            IP   ++ I  Y +HR P  +P P KFDPD FLPE   NRH +A+VPFSAGPR+C+G++
Sbjct: 391 LIPKEASIDIWIYDIHRNPKHWPEPEKFDPDRFLPENCVNRHPFAYVPFSAGPRNCIGQR 450

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +AM ++K I+  I++NF V    K    ++  D++L+ A    +   PR
Sbjct: 451 FAMYEMKAIICGIMQNFSVKLADKNEKVEIMTDLVLRSAHEINLNFIPR 499



 Score = 96.7 bits (230), Expect = 1e-18
 Identities = 60/227 (26%), Positives = 106/227 (46%), Gaps = 9/227 (3%)

Query: 65  FVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR 124
           F   S  +F+N  + S  Y     V +   P  +V +  P + E I S   +I K   Y 
Sbjct: 52  FYSDSVQLFKNFREWSRKYSPLYSVVVLDIP--VVVVTGPDEFEKIASGSKHITKGMIYG 109

Query: 125 FFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE--ASN 182
             +PWLG GLL ++G  W+  RK++ P FH ++L+ F+ +FN  +  +V+ +K+E   S 
Sbjct: 110 LVEPWLGKGLLTNSGSLWQQRRKILTPAFHFSILQEFVKVFNKETARLVETIKQENKKSA 169

Query: 183 FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLF 242
            +    +S+  +  + ET+ G +     +    Y  A+ +M  IL  R  + W     +F
Sbjct: 170 TNIIPLISQTALNTIAETSFGTTLDLTKKDDKNYVSAIHEMGKILIYRMVRPWFYSLFVF 229

Query: 243 KFTDYAKNQTK-LLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATT 288
                   + K +L  +H  T+++I  + ++F    KP  +N    T
Sbjct: 230 YILSSVGAKLKQVLSTLHSFTERIIPERSKDF----KPFEVNTDGET 272


>UniRef50_A1BPS2 Cluster: CYP4BF1; n=2; Ips paraconfusus|Rep:
           CYP4BF1 - Ips paraconfusus
          Length = 511

 Score =  213 bits (520), Expect = 1e-53
 Identities = 102/230 (44%), Positives = 153/230 (66%), Gaps = 3/230 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G K R AFLDLLL     G  ++DE+I+E+VDT MFEGHDTT++G S+ +  +  H D Q
Sbjct: 281 GGKTRRAFLDLLLSIQDEG-KLTDEDIREEVDTFMFEGHDTTSSGMSWTIWCLAHHLDYQ 339

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           +KVI+E+D +FG+SDR  T +D  E+KYLE+C+ E +RLYPPVP+I+R+V ++      G
Sbjct: 340 NKVIQEIDAVFGNSDRNCTNEDLKELKYLEQCIKEAMRLYPPVPLISRKVEEDFHCA--G 397

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             +P   T++I+   LHR P +Y N   ++P+NF P   A RH Y+F+PFSAGPR+C+G+
Sbjct: 398 YDVPRDATILISPLVLHRDPALYENVESYNPENFSPSAIARRHAYSFIPFSAGPRNCIGQ 457

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           K+A+++ + +LS   R + V S  +       A IILK ++G  +++  R
Sbjct: 458 KFALMEERTVLSWFFRRYCVRSSEEFLSNIPCAKIILKPSKGVPIKIYRR 507



 Score =  145 bits (352), Expect = 2e-33
 Identities = 80/277 (28%), Positives = 141/277 (50%), Gaps = 12/277 (4%)

Query: 21  FYVLLVPAVILWYAY-----WRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRN 75
           F+V +V  ++  YA      W + R+RL ++ D++           A +F     D    
Sbjct: 3   FWVPVVVLLLFVYATLRIWPWILKRKRLIQMVDRIPGPTAIPILGCAYQFRPKIEDFSYE 62

Query: 76  IVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLL 135
           +++ +  +    VV+ W+GP  +V  + P  V+ +L S+  I K +EY   + WLG GLL
Sbjct: 63  LLEYARLHKDSEVVRFWLGPIPIVCAFGPESVKTVLESNKVITKGDEYDILERWLGTGLL 122

Query: 136 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSEC 192
           ISTG KWRS RK++   FH NVL  F+D ++  +R  +D++++ A     FD   ++  C
Sbjct: 123 ISTGNKWRSRRKMLTMAFHFNVLNGFMDTYDKEARIFLDQIREFADTNEPFDVCPFIKRC 182

Query: 193 TVEILLETAMGVSKSTQDQSGFEY--AMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 250
            ++I+ ET+M      Q      Y  A+A M     L+ R    W++P  +++F  + +N
Sbjct: 183 ALDIICETSMAHKIDAQVDHNHPYVNAVAQMNTLSFLYARSPWFWIKP--IWRFFGHEEN 240

Query: 251 QTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETAT 287
             + L ++   T+ VI  +++E  + KK    N++ T
Sbjct: 241 YERNLKLVTDFTQNVIAERRKELHTAKKTVQENKSGT 277


>UniRef50_Q178T9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 511

 Score =  210 bits (513), Expect = 7e-53
 Identities = 142/475 (29%), Positives = 248/475 (52%), Gaps = 38/475 (8%)

Query: 85  HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144
           H+ +  I IGP++ + L  P  V+ +L+     +K+  Y   +  L NGLL S  + W+ 
Sbjct: 67  HDRMFAIHIGPKVAIGLSHPELVQQVLNHPYCQEKSNVYELLR--LPNGLLSSKYKVWKL 124

Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETA 201
           HRK +  TF+L +L SF+ +FN ++R ++  L + AS    F+    ++ CT+ ++ ET+
Sbjct: 125 HRKTLNSTFNLRILNSFLPIFNDSTRKLIQLLDQYASTGKTFNILAPLTHCTLGMVCETS 184

Query: 202 MGVSKSTQDQSGFEYAMAVMK-MCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHG 260
            G  K   ++ G E     ++ +   L  R   + L  +++++ T   +++TK   +   
Sbjct: 185 FG--KKVLEREGKEQFFDDLEVLLTSLGKRVVNVLLHSEIIYRLTPMYRDETKSRAVCRQ 242

Query: 261 LTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXX 320
            T KVI+ K+ E  S     +   +  T+E   G L+  EG ++                
Sbjct: 243 FTDKVIEEKRIEIESSFAGDS---SLITTE---GTLSDDEGEAY---------------- 280

Query: 321 GQKKRLAFLDLLLES---SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 377
             K+   F+D LL+    ++S    +D EI +QV T++  G++T+A   +    ++ ++ 
Sbjct: 281 --KRPQIFIDQLLKMPLMTKSAYNFTDLEISDQVFTMIIAGNETSATQMAHTCLLLAMNP 338

Query: 378 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 437
            IQ K  +E+ Q     +  +      ++ Y+E  L E++RL P   +I+R+  Q+I L 
Sbjct: 339 AIQQKAYQEVQQFIETENSYIDADILRKLVYIEAVLKESMRLLPVGSLISRKNLQDIVL- 397

Query: 438 SNGKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496
            +G  IP  T L++  Y LHRRPD++  +  +F P+ FL E S  RH YAF+PFS GPR 
Sbjct: 398 -DGHIIPKNTPLLMKPYSLHRRPDIWGSDAEQFVPERFLGEDSKRRHPYAFIPFSGGPRG 456

Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           C+G +YAM+ LK++L+ IL+NF + + LK  D ++   + L  A    V L+ R+
Sbjct: 457 CIGLRYAMMTLKIMLALILKNFEISTQLKYRDLRIHYQLSLNLAGPHAVSLERRR 511


>UniRef50_Q695H3 Cluster: Pheromone-degrading enzyme; n=2;
           Phyllopertha diversa|Rep: Pheromone-degrading enzyme -
           Phyllopertha diversa (Pale-brown chafer beetle)
          Length = 502

 Score =  210 bits (512), Expect = 1e-52
 Identities = 100/231 (43%), Positives = 152/231 (65%), Gaps = 3/231 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G+KK+ AFLDLLLE S +  + +++ I+E+VDT MFEGHDTTA   +F L  + ++  IQ
Sbjct: 271 GRKKKQAFLDLLLEYSANDPSFTEQHIQEEVDTFMFEGHDTTATSITFALYALAMNPHIQ 330

Query: 381 DKVIEELDQIFGD-SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           +K   EL +IF + S R  +++D  EMKYLE  + ETLR+Y  VP  +R + +++ +  N
Sbjct: 331 EKAYAELKEIFSNNSKRHASYRDLQEMKYLEMVIKETLRIYTTVPFYSRALEEDVNM--N 388

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G+ +P GT L +  Y +H  P +Y +P  FDP+ F  E S  R  +AF+PFSAGPR+C+G
Sbjct: 389 GQILPKGTMLNVFAYGVHHNPKIYKDPETFDPERFSIENSKERSPFAFIPFSAGPRNCIG 448

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +K+AML++K  +S +LRNF+++  +      L+++ +LK   G  VRLQ R
Sbjct: 449 QKFAMLEMKSSISDVLRNFKLLPSVPAHKVVLKSEAVLKSDNGVFVRLQKR 499



 Score =  167 bits (406), Expect = 7e-40
 Identities = 89/261 (34%), Positives = 142/261 (54%), Gaps = 5/261 (1%)

Query: 25  LVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYD 84
           L+ ++ILW  YW     + YE   K             +  +G       ++++ S  Y 
Sbjct: 9   LLCSLILWLVYWYYKINK-YEKYLKTVPGPARTPIMGNIPDIGSPVSFLEDLLKLS--YM 65

Query: 85  HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144
           ++   K++IG +  VFL +P+D+E +L+S   + K++ Y+F   WLG GLL S+G KW+ 
Sbjct: 66  YKGNFKLYIGAQPRVFLVEPKDLEFLLNSTSLLTKSKSYKFLYRWLGAGLLTSSGNKWKK 125

Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK--KEASNFDCHDYMSECTVEILLETAM 202
           HRK+I P FH  +L+ FID+FN+ S  +V+KL      S+ D + +++ CT++I+ ETAM
Sbjct: 126 HRKIITPAFHFQILEEFIDVFNSASDVLVEKLNAAPNKSSIDIYPFIARCTLDIICETAM 185

Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262
           G S   Q+    EY  +V  +  IL  R     L  DLL+ FT   + +   L ++HG T
Sbjct: 186 GTSVDAQNDINSEYVNSVKILLGILVQRSLSPILANDLLYPFTTTYQKEKAALKVVHGYT 245

Query: 263 KKVIKRKKEEFASGKKPSNLN 283
           K VI ++K EF +  K  + N
Sbjct: 246 KSVINKRKIEFYNNSKSEDRN 266


>UniRef50_UPI0000D55ACE Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 501

 Score =  209 bits (510), Expect = 2e-52
 Identities = 99/231 (42%), Positives = 146/231 (63%), Gaps = 5/231 (2%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G+KK+  FLDL+L ++  G ++S EEI+E+VDT MF GHDTT   +SF L  +  +++ Q
Sbjct: 275 GRKKKKVFLDLILSATTDGQSLSPEEIREEVDTFMFGGHDTTGTATSFILYCIANNKEAQ 334

Query: 381 DKVIEELDQIFGDSDRP-VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           +K++EE  Q+FGD   P VT+    EMKYLE  + E LRLY PVPI  R ++Q+     N
Sbjct: 335 EKILEEQKQLFGDERSPKVTYSTLQEMKYLENAIKEGLRLYSPVPIYGRLIDQDTEY--N 392

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G  IP G  ++I  + +H  P  YPNP KFDP  F  E +  +  + F+PFSAGPR+C+G
Sbjct: 393 GTMIPKGVGVIIFAHGIHMNPKYYPNPEKFDPSRF--ENTTGKDPFTFIPFSAGPRNCIG 450

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +KYAML++K ++S ++RNF +       +  L  + +LK   G ++ L+ R
Sbjct: 451 QKYAMLEIKSLVSKVVRNFELFPASPTHEMHLAPETVLKSLNGVKIGLKMR 501



 Score =  136 bits (329), Expect = 1e-30
 Identities = 78/261 (29%), Positives = 138/261 (52%), Gaps = 7/261 (2%)

Query: 16  SAINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRN 75
           S +  F++ LV  ++L + ++    RR+                  A EF   S+ +  N
Sbjct: 2   SVLTEFFIALVALILLPFYFYYTKIRRIENFFKHFPSPAGVPILGVAPEFKTTSS-VLDN 60

Query: 76  IVQKSADYDHESVVKIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGL 134
              K A   H ++V +  GP +  +   D + +E +LSS+  + K+   RF +PW+G GL
Sbjct: 61  F-HKYAKA-HGTMVHLKFGPFKHALLCTDTKFLEFLLSSNKLLKKSVNLRFLEPWIGTGL 118

Query: 135 LISTG-QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDC--HDYMSE 191
           + + G  KW++HRKLI P FH  +L+ F+D+F +    +V KL + + +  C  + Y+++
Sbjct: 119 VTADGGPKWKTHRKLITPAFHFKILEQFVDIFESGGDILVKKLSEVSGSKSCDIYPYITK 178

Query: 192 CTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQ 251
           CT++I+ ETAMG     Q+     Y  ++ +MC I  +R    +L  D +F+F+   K Q
Sbjct: 179 CTLDIICETAMGTKVDVQNTENSAYFESIKEMCRIFTVRTVGAFLSNDFIFRFSKDYKIQ 238

Query: 252 TKLLDIIHGLTKKVIKRKKEE 272
           TK + ++H  + +VI  K++E
Sbjct: 239 TKAVKVLHNHSNEVIVNKRKE 259


>UniRef50_Q170T4 Cluster: Cytochrome P450; n=5; Endopterygota|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 497

 Score =  209 bits (510), Expect = 2e-52
 Identities = 100/232 (43%), Positives = 154/232 (66%), Gaps = 6/232 (2%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G KK++AFLD+LL++S  G  ++D+EI+E+VDT MFEGHDTT    +F L ++  H ++Q
Sbjct: 269 GSKKKMAFLDVLLQASVDGKPLTDKEIQEEVDTFMFEGHDTTTIAIAFTLLLLARHPEVQ 328

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           +KV +E+ +I G D   P T+++  +MKYLE  + E+LRLYPPVPII R+  ++ T+   
Sbjct: 329 EKVYKEVTEIIGTDLSIPATYRNLQDMKYLEMVIKESLRLYPPVPIIGRKFTEKTTI--G 386

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHY-YAFVPFSAGPRSCV 498
           G  IP  +   +    +HR P ++ +P KFDP+ F PER+  +   YA++PFSAGPR+C+
Sbjct: 387 GNVIPEDSNFNLGIIVMHRDPKLFDDPEKFDPERFSPERTMEQSSPYAYIPFSAGPRNCI 446

Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           G+K+AML+LK  LS ++RN+R+     E    +Q  + LK  +G ++   PR
Sbjct: 447 GQKFAMLELKSTLSKVIRNYRLTEAGPEPQLIIQ--LTLKPKDGLKIAFVPR 496



 Score =  160 bits (388), Expect = 1e-37
 Identities = 72/188 (38%), Positives = 116/188 (61%), Gaps = 2/188 (1%)

Query: 87  SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146
           ++ ++W+G RL +F  +  D E +LSS   I K+E Y+F  PWLGNGLL+ST QKW + R
Sbjct: 66  TMFRVWVGTRLALFCTNTPDTETVLSSQKLIRKSELYKFLVPWLGNGLLLSTDQKWFNKR 125

Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAMGV 204
           K+I P FH  +L+ FI++F+  S  +V KLK EAS    + + Y++ C ++++ ETAMG 
Sbjct: 126 KIITPAFHFKILEQFIEVFDRQSGILVQKLKPEASGKLVNVYPYVTLCALDVICETAMGT 185

Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264
             + Q     +Y  AV ++  +L  R  K+W R D LF  +   K Q K++ ++H  T  
Sbjct: 186 PINAQTDVDSKYVRAVTELSYLLTTRFVKVWQRSDFLFNLSPDRKRQDKVIKVLHDFTTN 245

Query: 265 VIKRKKEE 272
           +I+++++E
Sbjct: 246 IIQKRRKE 253


>UniRef50_Q8ISJ8 Cluster: Cytochrome P450 CYP4S4; n=3;
           Noctuidae|Rep: Cytochrome P450 CYP4S4 - Mamestra
           brassicae (Cabbage armyworm)
          Length = 492

 Score =  208 bits (509), Expect = 2e-52
 Identities = 106/222 (47%), Positives = 146/222 (65%), Gaps = 6/222 (2%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G KKR A LDLLLE+   G  I  E I+E+V+T+MFEGHDTTA      L ++  H+++Q
Sbjct: 268 GGKKRYAMLDLLLEAENKG-EIDLEGIREEVNTLMFEGHDTTAMAIVLGLMLIADHEEVQ 326

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           D++ EE  +I GDSDR  T  D  +MKYLE  + ETLRLYP VP IAR++ ++  L  + 
Sbjct: 327 DRIFEECQKILGDSDRTPTMSDLADMKYLEAVIKETLRLYPSVPFIAREITEDFML--DD 384

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             +  G+ + I  Y LHRRPD++P P+ F PD FL    A  H YAFVPFSAGPR+C+G+
Sbjct: 385 LPVKKGSEVSIHIYDLHRRPDLFPEPDAFIPDRFL--SGAPMHPYAFVPFSAGPRNCIGQ 442

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEG 542
           ++AML++K + S I RNFR+   ++     L AD+++ R EG
Sbjct: 443 RFAMLEMKCVFSAICRNFRLAPKVQGYRPALLADMLI-RPEG 483



 Score =  128 bits (309), Expect = 4e-28
 Identities = 73/219 (33%), Positives = 119/219 (54%), Gaps = 5/219 (2%)

Query: 62  ALEFVGGSA-DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120
           ALEF+  S  ++F  + Q   +Y    V+K+    R ++ L + +DVEV+LS    I K+
Sbjct: 41  ALEFLKISPRELFLKMRQYKKEYGDRYVIKMM--KRRILHLSNEKDVEVVLSHSRNIKKS 98

Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-E 179
           + Y F + WLG GLL+S+G KW   RK++ PTFH N+LKSF  +    SR++V+ L   E
Sbjct: 99  KPYTFLEAWLGTGLLLSSGAKWHRRRKILTPTFHFNILKSFTVVMKEKSRSLVETLNNLE 158

Query: 180 ASNFDCHDYMSECTVEILLETAMGVSKSTQDQS-GFEYAMAVMKMCDILHLRHTKIWLRP 238
            +  +    +S+ T+  + ETAMG        S   EY  A++++ ++L  R T++WL  
Sbjct: 159 GTEVNLLPVISDYTLYTICETAMGTQLDADKSSKTLEYKTAILEIGNLLLGRLTRVWLHN 218

Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGK 277
           + LFK     +     L+ +H     VI  +K+ +  G+
Sbjct: 219 EYLFKKFPIGRRFENCLEKVHSFADDVIMERKKNWKPGQ 257


>UniRef50_O17851 Cluster: Putative uncharacterized protein cyp-37B1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein cyp-37B1 - Caenorhabditis elegans
          Length = 509

 Score =  208 bits (508), Expect = 3e-52
 Identities = 96/228 (42%), Positives = 151/228 (66%), Gaps = 3/228 (1%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           K+ +AFLDLLLE    G+ +++++I+E+VDT MFEGHDTT+A   + L  +  + + Q+K
Sbjct: 281 KRSMAFLDLLLELRNEGL-MNEDDIREEVDTFMFEGHDTTSASMGWTLWCLAHNPEFQEK 339

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           VI+E+D IFG SDR  T  D  +MKYLE+CL E+LR+YP VP   R V Q++ +  NG  
Sbjct: 340 VIQEVDGIFGTSDRDCTNDDLKQMKYLEKCLKESLRMYPSVPFFGRTVEQDVVI--NGDF 397

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
            P G  +++    L R P ++ NPN+++P+NF  ++  +RH Y+ +PFSAGPR+C+G+K+
Sbjct: 398 FPKGVRIIVMPLLLQRNPLIFDNPNQYNPENFSEDKIGSRHAYSDIPFSAGPRNCIGQKF 457

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           AM++ K ++S   R +RV +       K+  ++ILK + GF + +  R
Sbjct: 458 AMMEEKAVISWFFRKYRVTASQPFGMNKILPELILKSSLGFPLTVHHR 505



 Score =  122 bits (294), Expect = 3e-26
 Identities = 62/188 (32%), Positives = 100/188 (53%), Gaps = 3/188 (1%)

Query: 89  VKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148
           + +W+GP  L+ + +P+  + IL S+  I KAEEY    PWLG GLL STG KWR  RK+
Sbjct: 81  IGLWLGPVPLIAVINPQHAKEILESNEVITKAEEYDILFPWLGTGLLTSTGSKWRQRRKM 140

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 205
           + P FH  VL  F+ + +  ++  ++++K  A +    D   Y+    ++++ +T+MGV+
Sbjct: 141 LTPAFHFKVLNDFLSVHDYQAKVFLEQIKPYADSGKEVDLFPYIKRLALDVICDTSMGVT 200

Query: 206 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKV 265
              Q+    +Y  +V  + +       + WLR   L+  T       + L I+   TK V
Sbjct: 201 IDAQNNHDHQYVESVRLLSEYAFEWILRPWLRLKPLWYLTGPGHEYDRHLKIVTDFTKTV 260

Query: 266 IKRKKEEF 273
           IK K EEF
Sbjct: 261 IKEKWEEF 268


>UniRef50_UPI0000D55B03 Cluster: PREDICTED: similar to Cytochrome
           P450 4g1 (CYPIVG1); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1) -
           Tribolium castaneum
          Length = 492

 Score =  206 bits (503), Expect = 1e-51
 Identities = 102/229 (44%), Positives = 152/229 (66%), Gaps = 4/229 (1%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           FLD L+E +      +DEE+  +  +++  G D TA   S+ L M+ + QDIQDKV EEL
Sbjct: 262 FLDYLVELTDREGRWTDEELTNETRSVIMAGSDATALTLSYCLVMLAMFQDIQDKVYEEL 321

Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447
             +FGDSDR VT  D   ++YL+R + ETLR++P   +I R++  ++T+  +G  IP GT
Sbjct: 322 CSVFGDSDRFVTVDDLPHLQYLDRFIKETLRVFPVTSMIGRELTTDMTI--DGHFIPKGT 379

Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507
           ++      +HR P+ YP+P KFDPD FLPE  A RH   F+PFS GPR+C+G +YAM+ +
Sbjct: 380 SIGFPILYIHRNPEYYPDPLKFDPDRFLPEEVAKRHPCTFIPFSFGPRNCIGYRYAMMTM 439

Query: 508 KVILSTILRNFRVI-SDLKE-SDFKLQADIILKRAEGFQVRLQPRKRMA 554
           KVIL+T+LR+F+++ +  KE S+ K++ DI  K  EG+ VR++ RK +A
Sbjct: 440 KVILATLLRSFKMVHTPYKEISELKIKFDIATKVDEGYPVRMELRKNVA 488



 Score =  121 bits (292), Expect = 4e-26
 Identities = 69/251 (27%), Positives = 130/251 (51%), Gaps = 10/251 (3%)

Query: 25  LVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYD 84
           L+  VI  +  W    +  +  A K+          +A    GG+ +I  N V+  + Y 
Sbjct: 8   LIFTVIALWLLWSFLWKNFF--ATKIKGPWAFPLIGSAYVLFGGTHNILENTVRVVSKY- 64

Query: 85  HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144
              + K+W+G +L +F  +P D+++IL+    ++K E YR+ K   G+GL  S   +W+ 
Sbjct: 65  -RPLCKLWLGNKLTIFPSNPDDIQMILNRS--LEKEEGYRYIKTVFGHGLFTSPVSEWKG 121

Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETA 201
           HRK+I  T +  VL SF+D +N  +R +++KLK   K+  + D    M++CT++I+  + 
Sbjct: 122 HRKVIVSTLNQQVLNSFMDTYNIYTRELIEKLKIDTKDGQHIDMFPIMTQCTLDIICSSI 181

Query: 202 MGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261
           MG   +   +   ++ M + ++ ++  +R   I+L P+L +K +  +K   +L   I+  
Sbjct: 182 MGTQMNAMKEES-QFIMWMTRVAELAIIRMFNIYLWPELFWKLSPISKESHELDQKIYNY 240

Query: 262 TKKVIKRKKEE 272
            K VI  K+ +
Sbjct: 241 VKTVIHNKRHK 251


>UniRef50_UPI0000D55952 Cluster: PREDICTED: similar to Cytochrome
           P450 4d2 (CYPIVD2); n=2; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4d2 (CYPIVD2) -
           Tribolium castaneum
          Length = 501

 Score =  205 bits (500), Expect = 3e-51
 Identities = 99/231 (42%), Positives = 147/231 (63%), Gaps = 4/231 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G K+R A LD+LLE S +G  ++DE+I+E+VDT MFEGHDTT     F L  +  + D+Q
Sbjct: 273 GIKRRAALLDMLLEVSDNGKNLTDEDIREEVDTFMFEGHDTTTTSICFVLYAIAQNPDVQ 332

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
            K+ +EL  + G D  + +TF D  E+KYL+  + E  RLYPPVP+I R + ++ T+  +
Sbjct: 333 KKIYDELVSVLGPDCKKEITFSDIQELKYLDVVIKEAHRLYPPVPLIERSLEEDCTI--D 390

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G  IP  T + I  Y ++   DVYP P+ FDPD FLPE+   RH +A+VPFSAGPR+C+G
Sbjct: 391 GLTIPKNTNISIFLYGMNYNKDVYPEPHVFDPDRFLPEKQGERHTFAYVPFSAGPRNCIG 450

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +K+A+L+LK  ++ +LR F +  D K    ++    +LK   G  + L+ +
Sbjct: 451 QKFALLELKTTIAKLLRCFEISPDPKNPP-QVGMCSVLKSRNGIHMFLKKK 500



 Score =  165 bits (402), Expect = 2e-39
 Identities = 80/192 (41%), Positives = 119/192 (61%), Gaps = 5/192 (2%)

Query: 87  SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146
           +VVK+W+GPRL + +  P  VE  L+S V+++K++ Y  FKPWLG+GLL+STG KW++ R
Sbjct: 69  TVVKVWLGPRLHLLITKPEMVEFFLNSTVHLNKSDGYDLFKPWLGDGLLVSTGSKWKTRR 128

Query: 147 KLIAPTFHLNVLKSFIDL-FNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETA 201
           KLI PTFH  +L++F++  FN     ++D L KEAS  D     H  ++ C+++I+ ETA
Sbjct: 129 KLITPTFHFKILENFLETSFNKQINILLDVLLKEASQTDKSIEIHSLINLCSLDIICETA 188

Query: 202 MGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261
            G   + Q +   +Y  AV    +I  LR    WLR  L+F+ +D      + L I+H  
Sbjct: 189 FGTELNAQAKCNPKYVEAVTGFLEIFTLRFFSAWLRHPLIFRLSDKYAKYMEYLKILHDF 248

Query: 262 TKKVIKRKKEEF 273
           T  +IKR+KEEF
Sbjct: 249 TNTIIKRRKEEF 260


>UniRef50_Q27472 Cluster: Cytochrome p450 family protein 32A1; n=3;
           Bilateria|Rep: Cytochrome p450 family protein 32A1 -
           Caenorhabditis elegans
          Length = 529

 Score =  204 bits (497), Expect = 6e-51
 Identities = 95/234 (40%), Positives = 160/234 (68%), Gaps = 4/234 (1%)

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           +KKR AFLDLLL   +    +SDE+I+E+VDT MFEGHDTT++G  F +  +G + + Q 
Sbjct: 289 EKKRKAFLDLLLTIQKEEGTLSDEDIREEVDTFMFEGHDTTSSGIGFTILWLGFYPECQK 348

Query: 382 KVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS-N 439
           K+ +ELD++FG ++++P +  D  +  YLE+C+ E+LR++P VP+IAR++++++T+   +
Sbjct: 349 KLQKELDEVFGFETNQPPSMDDIKKCSYLEKCIKESLRMFPSVPLIARRLSEDVTINHPS 408

Query: 440 GKKI--PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 497
           G+KI  PAG    ++     R P  +P+P+ ++PDNF  +  A R  YA++PFSAGPR+C
Sbjct: 409 GQKIVLPAGLAACVSPIAAARDPRAWPDPDTYNPDNFDIDAIAGRDPYAYIPFSAGPRNC 468

Query: 498 VGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           +G+K+A+L+ K ILST  R + V S   E + +   ++IL+   G +++++ R+
Sbjct: 469 IGQKFALLEQKTILSTFFRKYEVESLQTEENLRPVPELILRPYNGMKIKIKRRE 522



 Score =  118 bits (283), Expect = 5e-25
 Identities = 58/190 (30%), Positives = 102/190 (53%), Gaps = 6/190 (3%)

Query: 86  ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 145
           + ++ +WIGP  +VFL     +  +L S+  I K  +Y     W+G GLL ST +KW   
Sbjct: 91  DGIMLLWIGPVPIVFLGTSECIRPVLESNTNISKPSQYDKMSEWIGTGLLTSTHEKWFHR 150

Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVD--KLKKEASNFDCHDYMSECTVEILLETAMG 203
           RK++ PTFH  +++ +  +F  N+  + D  +L  +   FD   Y   CT++I+ ETAMG
Sbjct: 151 RKMLTPTFHFTIIQDYFPVFVRNAEVLADAVELHVDGDYFDAFPYFKRCTLDIICETAMG 210

Query: 204 VSKSTQDQSGFEYAMAVMKMCDIL--HLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261
           +  + Q     EY  AV ++ +I+  H++   +WL+P  ++  T       + + + +  
Sbjct: 211 IQVNAQLGHNNEYVHAVKRISEIVWNHMKFPWLWLKP--IWYLTGLGFEFDRNVRMTNNF 268

Query: 262 TKKVIKRKKE 271
            +KVI+ +KE
Sbjct: 269 VRKVIQERKE 278


>UniRef50_Q9U1R5 Cluster: Putative uncharacterized protein cyp-42A1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein cyp-42A1 - Caenorhabditis elegans
          Length = 511

 Score =  203 bits (496), Expect = 8e-51
 Identities = 93/229 (40%), Positives = 159/229 (69%), Gaps = 5/229 (2%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           ++R+AFLDL+L+ +  G  +  E I E+VDT  FEGHDTT+A  ++FL +MG + +IQ K
Sbjct: 280 RRRMAFLDLMLDMNSKG-ELPMEGICEEVDTFTFEGHDTTSAAMNWFLHLMGANPEIQSK 338

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           V +E+D++ G++DRPV+++D  ++KYLE C  ETLRLYP VP+IARQ  ++I +   G  
Sbjct: 339 VQKEIDEVLGEADRPVSYEDLGKLKYLEACFKETLRLYPSVPLIARQCVEDIQV--RGHT 396

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           +P+GT +V+    +H+ P  + +P  F+P+ F+      +H YA++PFSAG R+C+G ++
Sbjct: 397 LPSGTAVVMVPSMVHKDPRYWDDPEIFNPERFI--TGELKHPYAYIPFSAGSRNCIGMRF 454

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           AM++ K IL+ IL+N +V + L+  + ++ A++I++   G +++ + R+
Sbjct: 455 AMMEEKCILAIILKNLKVKAKLRTDEMRVAAELIIRPLYGNELKFEKRE 503



 Score =  127 bits (307), Expect = 7e-28
 Identities = 68/206 (33%), Positives = 108/206 (52%), Gaps = 5/206 (2%)

Query: 86  ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 145
           E + ++W+G    V LY   +VE IL S   ++K   Y F   W+G+GLLIS   KWR  
Sbjct: 72  ERITRVWLGGLPFVLLYGAHEVEAILGSPKMLNKPFLYGFLSAWIGDGLLISKPDKWRPR 131

Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDY---MSECTVEILLETAM 202
           RKL+ PTFH ++LK F++++N + R ++ K + +A   +  D    ++ CT++++ E A+
Sbjct: 132 RKLLTPTFHYDILKDFVEVYNRHGRTLLSKFEAQAGTGEYSDVFHTITLCTLDVICEAAL 191

Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262
           G S + Q      Y  AV KM DI+  R  +     D +F      K   + + I+H  T
Sbjct: 192 GTSINAQKDPHSPYLDAVFKMKDIVFQRLLRPHYFSDTIFNLIGPGKEHDECVKILHEFT 251

Query: 263 KKVI--KRKKEEFASGKKPSNLNETA 286
            K I  ++ K + A G +     ETA
Sbjct: 252 SKAIYARKAKVDAAGGVEQLLAQETA 277


>UniRef50_UPI0000D56462 Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily v, polypeptide 2; n=2;
           Tribolium castaneum|Rep: PREDICTED: similar to
           cytochrome P450, family 4, subfamily v, polypeptide 2 -
           Tribolium castaneum
          Length = 814

 Score =  202 bits (493), Expect = 2e-50
 Identities = 127/407 (31%), Positives = 214/407 (52%), Gaps = 33/407 (8%)

Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLE 199
           W+ HR++I PT + ++L +F  +       +++ L+K+      D + +++   V+++ E
Sbjct: 433 WKKHRRIIVPTLNQSILNTFPQIICQQCDILLEILEKKCDKGEIDHYKFVTNFAVDVVSE 492

Query: 200 TAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH 259
           T  GV  + Q      Y+    K+ +++ +R  ++    D LF +T   K + + + ++ 
Sbjct: 493 TIFGVPLNAQITDA-NYSRTFDKIMEVVFMRIFRVDYHSDFLFSWTKEYKAEQENVKLVK 551

Query: 260 GLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXX 319
             T+ +I+R        KK           E  T +L  VEGL                 
Sbjct: 552 ETTRDLIER--------KK-----------EQITCQL-EVEGLC----DWFISDSSRILV 587

Query: 320 XGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
             +KKR  FLD+L+        +S +E++++V T +  G DT A    F L+++G+HQD+
Sbjct: 588 VEEKKR-PFLDVLV-GKYLNEELSYQELEDEVSTFLLAGSDTNATAGCFVLTLLGMHQDV 645

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q+K+ EE+ ++ G    P T  D  ++KY ER + ETLRL+P  P IAR  + +I L   
Sbjct: 646 QEKLYEEIIEVLGPEKYP-TLDDLPKLKYTERVIKETLRLFPGAPFIARIASDDIDL--G 702

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
              IP G+ + +    LHR    +  P KF+P+ FLPE  A RH Y ++PFS G R+CVG
Sbjct: 703 DYVIPRGSNIAVGYVHLHRSEKYWEEPLKFNPERFLPENVAKRHPYTWLPFSGGLRNCVG 762

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKE-SDFKLQADIILKRAEGFQV 545
            K+ M+ +K+++S I+R FRV S +K   D +L A+I+LK   GF++
Sbjct: 763 GKFGMMVMKIMISMIIRKFRVKSSVKSVGDIELTANIVLKPKNGFRL 809


>UniRef50_UPI0000D56049 Cluster: PREDICTED: similar to Probable
           cytochrome P450 4d14 (CYPIVD14); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Probable cytochrome
           P450 4d14 (CYPIVD14) - Tribolium castaneum
          Length = 487

 Score =  201 bits (490), Expect = 4e-50
 Identities = 103/243 (42%), Positives = 150/243 (61%), Gaps = 8/243 (3%)

Query: 309 GLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSF 368
           G K         G+KK  AFLDLLL+ S     +SD +I+E+VDT MF GHDTTA G  F
Sbjct: 247 GRKTNRNETEKSGKKK--AFLDLLLKFSDIE-KLSDRDIREEVDTFMFAGHDTTATGVCF 303

Query: 369 FLSMMGIHQDIQDKVIEELDQIFGDSDRP-VTFQDTLEMKYLERCLMETLRLYPPVPIIA 427
            L ++  + ++Q+KV+ E  ++FGD   P VT+Q+   MKYLE  + ETLRLYP VP+I 
Sbjct: 304 ALYLLANNPEVQEKVLSEQKELFGDEKNPCVTYQELQNMKYLEYVIKETLRLYPSVPVIG 363

Query: 428 RQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAF 487
           R + ++ T     + I A T + I  Y +HR PD +P P KF P+ F  E   N   YA+
Sbjct: 364 RYLKEDTTF--GDRVISAKTNVAIFIYGIHRNPDYFPEPEKFIPERF--ENMTNLPPYAY 419

Query: 488 VPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRL 547
           +PFSAGPR+C+G+K+AML++K ++S ++R+F +       +  L A+ +LK A G ++ L
Sbjct: 420 IPFSAGPRNCIGQKFAMLEMKSLISKVIRHFELTPANPHHELVLAAETVLKSANGIKIGL 479

Query: 548 QPR 550
           + R
Sbjct: 480 RAR 482



 Score =  120 bits (290), Expect = 8e-26
 Identities = 65/203 (32%), Positives = 109/203 (53%), Gaps = 7/203 (3%)

Query: 88  VVKIWIGPRLLVFLY-DPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146
           +VK+ +GP     +  D + VE  LSS+  + K++ Y F + WLGNGL+++ G  W+ HR
Sbjct: 64  IVKLRLGPFFKALVVTDYKLVEFFLSSNSLLTKSQNYAFARSWLGNGLILANGTHWKQHR 123

Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEILLETAMGV 204
           K++ P FHL +L+ +++ F++  R  ++KLK      + D    +  CT++++ ETAMG 
Sbjct: 124 KILTPAFHLEILREYLETFDSVGRIFIEKLKSLDNVQSVDLDALVPLCTLDVICETAMGT 183

Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264
             + Q     EY  +V +MC I+  R           +  T     + K+++I+H  T K
Sbjct: 184 KINAQKGENSEYVSSVKEMCRIIVARFLSPLKILKCTYWMTHDFYTERKVVNILHSFTSK 243

Query: 265 VIKRKK----EEFASGKKPSNLN 283
           VI  +K    E   SGKK + L+
Sbjct: 244 VIDGRKTNRNETEKSGKKKAFLD 266


>UniRef50_Q7YXL0 Cluster: Cytochrome P450 monooxygenase; n=2;
           Tribolium castaneum|Rep: Cytochrome P450 monooxygenase -
           Tribolium castaneum (Red flour beetle)
          Length = 491

 Score =  200 bits (489), Expect = 6e-50
 Identities = 91/229 (39%), Positives = 146/229 (63%), Gaps = 3/229 (1%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           +KRLA LDLLL+    G  I DE I+E+VDT MFEGHDTT+    + L ++  H+++Q++
Sbjct: 264 RKRLAMLDLLLKYKSEGANIDDEGIREEVDTFMFEGHDTTSVSICYTLMLLANHREVQEE 323

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           +++E++ +    + P T+    E+K+++R + E+LRLYP VP I+R    EI   + G  
Sbjct: 324 ILKEMEAVL--DEEPPTYAKLQELKFMDRVIKESLRLYPSVPFISRVSGSEIQTKT-GYT 380

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           IP    + +  Y +H  P+V+P+P KFDPD FLPE    RH +A++PFSAG R+C+G+K+
Sbjct: 381 IPKDCMVNLQIYDMHHNPNVFPDPEKFDPDRFLPENIQKRHPFAYIPFSAGSRNCIGQKF 440

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           AML++K +L  IL+ F + +     D    +D++L+     +V+  PR+
Sbjct: 441 AMLEIKTVLCGILKKFILEAVDTRKDMAFVSDLVLRPKGSIKVKFVPRR 489



 Score =  118 bits (284), Expect = 4e-25
 Identities = 59/184 (32%), Positives = 99/184 (53%), Gaps = 2/184 (1%)

Query: 99  VFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVL 158
           V L +P DVE++L+      K+  Y F   WLG GLL S G KW++ RK++ P FH N+L
Sbjct: 80  VNLLNPEDVELVLTDTKQNTKSFIYHFLHSWLGTGLLTSRGPKWQNRRKILTPAFHFNIL 139

Query: 159 KSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEY 216
           + FI +FN  ++ +V+ L+ E+     D    +++ T+  + ETAMG+  +  D     Y
Sbjct: 140 QEFIQIFNEETKRLVEDLEAESHKPYIDVVVPITQFTLLSIGETAMGIKLNASDNDKDGY 199

Query: 217 AMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASG 276
             AV K+  +L  R  + W+  + ++  T   + + K+L  +H  +  VI  +K+ F+S 
Sbjct: 200 KRAVYKIGQLLTYRAPRPWIHNETIYSLTPQGRKEQKVLKSLHSFSNNVIAERKKHFSSS 259

Query: 277 KKPS 280
              S
Sbjct: 260 SYSS 263


>UniRef50_UPI00015B569E Cluster: PREDICTED: similar to cytochrome
           P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 512

 Score =  198 bits (483), Expect = 3e-49
 Identities = 94/219 (42%), Positives = 148/219 (67%), Gaps = 3/219 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           G++KR AFLDLLL +S++    ++ EE++E+VDT MF GHDTT++  S+ L  +    +I
Sbjct: 281 GKRKRKAFLDLLLSASENASNPLTFEELREEVDTFMFAGHDTTSSAISWGLFALANAPEI 340

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q KV +EL +IFGDS      +   E+KYL+R + E LRLYP  P+++R++  +  + ++
Sbjct: 341 QAKVHKELQEIFGDSGETANSKQLSELKYLDRVIKEVLRLYPSAPMVSRRLTHDTVIDNH 400

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
              +P GT + I  Y++H  P V+ +P  FDPD FLPE   +RH Y++VPFSAGPR+C+G
Sbjct: 401 --HVPKGTFVNIHIYQMHHDPKVWKDPETFDPDRFLPENIRSRHPYSYVPFSAGPRNCIG 458

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILK 538
           +K+A+L++K  L+ ILR +++ S LK ++ K+    IL+
Sbjct: 459 QKFALLEVKTALTAILRKWQISSVLKPTEIKMIHTFILR 497



 Score =  116 bits (278), Expect = 2e-24
 Identities = 64/190 (33%), Positives = 102/190 (53%), Gaps = 5/190 (2%)

Query: 88  VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 147
           +V  W+G + +V L  P+ +EVIL S+  I KA  Y + KPWLG+GL+ STG+ W SHR+
Sbjct: 73  MVLAWVGTQPIVILRRPQQMEVILPSNTLITKAATYDYMKPWLGDGLVTSTGELWFSHRR 132

Query: 148 LIAPTFHLNVLKSFIDLFNAN----SRAVVDKLKKE-ASNFDCHDYMSECTVEILLETAM 202
           LI P FH  VL+ +  +           +  +LK +  +  +    + + T++ + ETAM
Sbjct: 133 LITPAFHFGVLEEYGAVMREKVEIFKECIESELKTDPKAPINIFGLVVKYTLDTICETAM 192

Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262
           GV+  TQ      Y  AV     +   R  K WL+ + ++  T+  K     + I+H  T
Sbjct: 193 GVNIDTQRNPESAYVKAVHTYARLTVERFYKPWLKWNAIYYRTNKGKEALNAVKIMHSFT 252

Query: 263 KKVIKRKKEE 272
           +KVI++K+ E
Sbjct: 253 EKVIRQKQAE 262


>UniRef50_Q179B7 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 543

 Score =  198 bits (483), Expect = 3e-49
 Identities = 139/535 (25%), Positives = 257/535 (48%), Gaps = 22/535 (4%)

Query: 23  VLLVPAVILWYAYWRM-SRRRLYELADKLNXXX--XXXXXXNALEFVGGSADIFRNIVQK 79
           +L V  ++     W + S+RR Y  AD L             AL F     D F  +V+ 
Sbjct: 2   LLAVTVIVGLITIWLLLSQRRRYRFADSLPQLKPWFPVVGNGALMFGKSDVDRFDVLVKI 61

Query: 80  SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139
             DYD   +V++W GP++L+F   P  V+ +L+S   ++K   Y F       GL  S  
Sbjct: 62  FRDYDR--MVRVWAGPKMLLFTSHPDLVQQLLTSPACLEKPFLYSF--AGFEQGLFTSKY 117

Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEIL 197
           + WRS RK +  +F+L +L  FI +F   +R +V+ L +  + +    H + S CT+E+ 
Sbjct: 118 KLWRSMRKRLNSSFNLRILHGFIPVFVQCARKMVEDLNENPDGTVVSMHKFTSVCTLEMA 177

Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257
             T +G S  T+ +   E+   +         R   + L P++++  T Y +   +   +
Sbjct: 178 CGTTLG-SDITRREGKEEFVHGLDIAFGEAARRMVSVHLYPNIVYHLTKYHRELVQARGV 236

Query: 258 IHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXX 317
           +     +V          G   S++ +          +  +   L+  + +  +      
Sbjct: 237 VCDFFSRVSLFPP---FFGVIMSHIIDCCMFYFQLVTERRNTMSLNCNKKTNEEELDF-- 291

Query: 318 XXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 377
                +K    +D LL  ++ G + SD EI++ +  ++   +DT+    +     +  ++
Sbjct: 292 ----DRKPKILIDQLLSVNRDGKSFSDTEIEDNIYAVITGANDTSGLLIAHACLFLCFYK 347

Query: 378 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 437
           DI++K+  E+ +   + +  +  +   ++ YLE+ L E LR  P  P I+R+   EI + 
Sbjct: 348 DIEEKLFTEIMEFMPNEEFEINPESLKQLSYLEKFLKECLRHCPVAPNISRENMSEIEI- 406

Query: 438 SNGKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496
            +G K+P G   ++  Y LHRR D++ P+ +KFDP+ F  ERS NRH +A++PFS G R 
Sbjct: 407 -DGMKVPPGNIFIMNFYALHRRKDIWGPDADKFDPEQFSEERSRNRHPFAYLPFSGGNRI 465

Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           C+G +YAM  +KV+L  ++RNF+  ++++    + + D+ +K      +++  RK
Sbjct: 466 CIGWRYAMFSMKVMLIYLIRNFQFETEIRPEQVRYRHDLTMKLPFEHMIKVTRRK 520


>UniRef50_Q16IS6 Cluster: Cytochrome P450; n=12; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 510

 Score =  196 bits (477), Expect = 2e-48
 Identities = 100/231 (43%), Positives = 143/231 (61%), Gaps = 5/231 (2%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           KKR A LD LL + Q  + I +  I+E+VDT  FEGHDTTAA   F    +     +QD+
Sbjct: 282 KKRYAMLDSLLLAEQKQL-IDEAGIREEVDTFAFEGHDTTAAALVFIFFTLAREPAVQDR 340

Query: 383 VIEELDQIFGD---SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           +  E+ Q++ +   S R  T QD  EMK+L+R L E LRL+PPV  I+R ++++I L  +
Sbjct: 341 IYREILQVYSNKPQSSRAFTPQDYSEMKFLDRALKECLRLWPPVTFISRSISEDIIL-DD 399

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G  IPAG    I    +H  P+ +P+P +FD D FLPE+   R+ YA+VPFSAGPR+C+G
Sbjct: 400 GSLIPAGCVANIHIMDMHHDPEQFPDPERFDADRFLPEQVDRRNPYAYVPFSAGPRNCIG 459

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +KYAM++LKV++   L  FRV+   K  D    AD++L+     +VR + R
Sbjct: 460 QKYAMMELKVVVVNALLKFRVLPVTKLEDINFVADLVLRSTNPIEVRFERR 510



 Score = 98.3 bits (234), Expect = 5e-19
 Identities = 63/195 (32%), Positives = 95/195 (48%), Gaps = 5/195 (2%)

Query: 90  KIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148
           + W    L V  +   R+ E ILSS   IDK+  Y+F  P+LG GLL S G KW   R++
Sbjct: 76  RFWFSSTLYVLNVVRVREAEHILSSTRNIDKSRFYKFLHPFLGLGLLNSNGSKWMHRRRI 135

Query: 149 IAPTFHLNVLKSFIDLFNANS---RAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVS 205
           + P+FH N+L  F   F        A +D+   +         MS+ T+  + ET+MGV 
Sbjct: 136 LTPSFHFNILNGFHHTFVEECDQLLATIDEHVDKGVPTALQPVMSKFTLNTICETSMGVK 195

Query: 206 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKV 265
            ST   +   Y   + ++ ++L  R  + WL  D L + T Y     KLL  +H  T  +
Sbjct: 196 LSTVSGADV-YRTKLYEIGEVLVHRLMRPWLLNDFLCRLTGYKAAFDKLLLPVHLFTTGI 254

Query: 266 IKRKKEEFASGKKPS 280
           I  K+++F    +PS
Sbjct: 255 INMKRKQFQESLEPS 269


>UniRef50_UPI0000E46144 Cluster: PREDICTED: similar to
           ENSANGP00000019301; n=5; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to ENSANGP00000019301
           - Strongylocentrotus purpuratus
          Length = 469

 Score =  195 bits (475), Expect = 3e-48
 Identities = 85/178 (47%), Positives = 127/178 (71%), Gaps = 2/178 (1%)

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           ++KR+AFLDLLL+  +     + E I+E+VDT MFEGHDTTAA  ++ L ++G H  +Q 
Sbjct: 280 KRKRIAFLDLLLQMHREDATFTLEAIREEVDTFMFEGHDTTAAAVNWALLLIGQHPTVQA 339

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           ++ +E+DQ+FGDS+RP+T  D  E+ YL   + E+LRL P VP I R ++++I +  NGK
Sbjct: 340 RLHDEIDQVFGDSERPITSDDLSELSYLSCVVKESLRLLPSVPGIGRDLDEDIIV--NGK 397

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
            +P G ++ ++ Y +H  P+ +P+P +FDPD FLPE S  RH +AF+PFSAGPR+C+G
Sbjct: 398 VVPKGASVFLSIYGIHHDPEQFPDPERFDPDRFLPENSTKRHPFAFIPFSAGPRNCIG 455



 Score =  149 bits (362), Expect = 1e-34
 Identities = 78/228 (34%), Positives = 124/228 (54%), Gaps = 5/228 (2%)

Query: 42  RLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHES--VVKIWIGPRLLV 99
           R++ L  K +         N L+F     + F   V     Y H+S  V+++W GP  +V
Sbjct: 31  RIFLLISKFDGPPAVPIFGNTLQFKSDPREHFLYDVGVREKYRHQSGGVIRMWFGPLPIV 90

Query: 100 FLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLK 159
            +Y+    E +++S  +I+K  EY F +PWLG GLL S GQKW   RKL+ PTFH ++L+
Sbjct: 91  LIYNAVHCEALMNSSRHINKGTEYTFMEPWLGKGLLTSGGQKWFHRRKLLTPTFHFSILQ 150

Query: 160 SFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEY 216
           SF+++FN  S  +V KL K   E+   +    ++ C ++I+ +TAMG   + Q  +  EY
Sbjct: 151 SFMEVFNEQSMILVKKLGKFADESETVNIFPLVTHCVLDIICDTAMGKRTNAQSDNENEY 210

Query: 217 AMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264
             AV +M  ++  R     L PD ++  TD  K+  K L I+HG+ ++
Sbjct: 211 VKAVGRMSHLIVSRIRNFMLWPDWIYNRTDAGKDHEKALQILHGMIQE 258


>UniRef50_Q9N574 Cluster: Cytochrome p450 family protein 31A3; n=4;
           Nematoda|Rep: Cytochrome p450 family protein 31A3 -
           Caenorhabditis elegans
          Length = 511

 Score =  195 bits (475), Expect = 3e-48
 Identities = 96/227 (42%), Positives = 148/227 (65%), Gaps = 4/227 (1%)

Query: 325 RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVI 384
           RLAFLDLLLE  +SG  + + +++ +VDT MFEGHDTT+ G  + + ++G H ++Q KV 
Sbjct: 284 RLAFLDLLLEMVKSG-QMDETDVQAEVDTFMFEGHDTTSTGLMWAIHLLGNHPEVQRKVQ 342

Query: 385 EELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIP 444
            ELD++ GD D  VT +    MKYLE  L E LRL+P VPII R+++ +  +   G  IP
Sbjct: 343 AELDEVMGD-DEDVTIEHLSRMKYLECALKEALRLFPSVPIITRELSDDQVI--GGVNIP 399

Query: 445 AGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAM 504
            G T ++  Y +HR P  + +P+ FDPD FLPE S  R  +AF+PFSAG R+C+G+++A+
Sbjct: 400 KGVTFLLNLYLVHRDPSQWKDPDVFDPDRFLPENSIARKSFAFIPFSAGSRNCIGQRFAL 459

Query: 505 LKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           ++ KVI++ +LRNF V +     + + + +II++      ++L  R+
Sbjct: 460 MEEKVIMAHLLRNFNVKAVELMHEVRPKMEIIVRPVTPIHMKLTRRR 506



 Score =  105 bits (251), Expect = 4e-21
 Identities = 77/268 (28%), Positives = 119/268 (44%), Gaps = 22/268 (8%)

Query: 23  VLLVPAVIL-WYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSA 81
           VLL  A I+ W  Y  +   R+ +    LN         + L            ++    
Sbjct: 8   VLLASATIIAWLLYKHL---RMRQALKHLNQPRSYPIVGHGLVTKPDPEGFMNQVIGMGY 64

Query: 82  DYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQK 141
            Y    +  +WIGP   + LY    VE I SS  +++K   Y   +PWLG  +L S  ++
Sbjct: 65  LYPDPRMCLLWIGPFPCLMLYSADLVEPIFSSTKHLNKGFAYVLLEPWLGISILTSQKEQ 124

Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEILLE 199
           WR  RKL+ PTFH ++LK F+ +FN  S+ +V K+         D    ++ CT++I+ E
Sbjct: 125 WRPKRKLLTPTFHYDILKDFLPIFNEQSKILVQKMCSLGAEEEVDVLSVITLCTLDIICE 184

Query: 200 TAMGVSKSTQDQSGFEYAMAVMKMCDILHLR--HTKIWLR--------------PDLLFK 243
           T+MG +   Q     EY  AV  +  ++  R  +  +W                  +LF 
Sbjct: 185 TSMGKAIGAQLAENNEYVWAVHTINKLISKRTNNPLMWNSFIYNLYDSFIIKKVNSILFF 244

Query: 244 FTDYAKNQTKLLDIIHGLTKKVIKRKKE 271
            T+  +   K L I+H  TKKVI  +KE
Sbjct: 245 RTEDGRTHEKCLRILHDFTKKVIVERKE 272


>UniRef50_Q9N4Q5 Cluster: Cytochrome p450 family protein 32B1; n=2;
           Caenorhabditis|Rep: Cytochrome p450 family protein 32B1
           - Caenorhabditis elegans
          Length = 516

 Score =  194 bits (473), Expect = 5e-48
 Identities = 102/237 (43%), Positives = 155/237 (65%), Gaps = 5/237 (2%)

Query: 322 QKKRLAFLDLLLESSQSGVAI-SDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           + K+LAFLD LL+S +    I +DE I+E+VDT MFEGHDTT++G +F +  +G   + Q
Sbjct: 280 ETKKLAFLDYLLKSQEEHPDILTDEGIREEVDTFMFEGHDTTSSGITFAVWFLGQFPEYQ 339

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
            +V +ELD+IFG D +R    +D  +M YLE+C+ ETLR+ PPVP ++R++ +++ +P  
Sbjct: 340 QRVHDELDEIFGEDFERIPNSEDIQKMVYLEQCIKETLRMTPPVPFVSRKLTEDVKIPHA 399

Query: 440 GKK---IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496
            K    +PAG   +I    + +    +  P +F P++F PER A R  +AFVPFSAGPR+
Sbjct: 400 TKPDLLLPAGINCMINIITIMKDARYFERPYEFFPEHFSPERVAAREPFAFVPFSAGPRN 459

Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRM 553
           C+G+K+A+L+ KV+LS I RNF V S  K  +     ++ILK   G QV L+ R+++
Sbjct: 460 CIGQKFALLEEKVLLSWIFRNFTVTSMTKFPEEMPIPELILKPQFGTQVLLRNRRKL 516



 Score =  128 bits (308), Expect = 5e-28
 Identities = 69/203 (33%), Positives = 115/203 (56%), Gaps = 7/203 (3%)

Query: 84  DHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWR 143
           D+  V+K+W+GP   V +      +++L S V I K+ +Y   K W+G+GLLISTG KWR
Sbjct: 79  DNCGVLKLWLGPIPAVNIARGEIAKIVLDSSVNISKSSQYNKLKEWIGDGLLISTGDKWR 138

Query: 144 SHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLET 200
           S RK++  TFH  VLK +  +F A  + +V+ L+  A+N   FD   Y+  C ++I+ ET
Sbjct: 139 SRRKMLTQTFHFAVLKEYQKIFGAQGKILVEVLQLRANNKFSFDIMPYIKRCALDIICET 198

Query: 201 AMGVSKSTQDQSGFEYAMAVMKMCDIL--HLRHTKIWLRPDLLFKFTDYAKNQTKLLDII 258
           AMG S S+Q  +  EY  +V ++ +I+  + +  + WL+P + + F D      + + + 
Sbjct: 199 AMGCSISSQRGANDEYVNSVRRLSEIVWNYEKAPQFWLKP-IWYLFGD-GFEFNRHVKLT 256

Query: 259 HGLTKKVIKRKKEEFASGKKPSN 281
              T+ VI+ +K+E  +     N
Sbjct: 257 TDFTRDVIENRKKELKTHNSEQN 279


>UniRef50_Q7YSZ3 Cluster: P450 enzyme precursor; n=1; Rhodnius
           prolixus|Rep: P450 enzyme precursor - Rhodnius prolixus
           (Triatomid bug)
          Length = 512

 Score =  192 bits (467), Expect = 3e-47
 Identities = 96/230 (41%), Positives = 148/230 (64%), Gaps = 3/230 (1%)

Query: 323 KKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           K + AFL++L++   +S   ++D++I+E+VD  MF GHDTTA+   F L ++G H  +Q+
Sbjct: 283 KGKKAFLNILIDLEDKSKGTLTDKDIREEVDNFMFAGHDTTASCIMFTLYLLGRHPHVQE 342

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           K  EEL +IFG+SDR V  +D   M YLE  + E++R+YPP P  +R + Q++ L  +  
Sbjct: 343 KAFEELYEIFGESDREVNNKDLHGMHYLEMIIKESIRIYPPAPYFSRNLIQDLVL-KDKT 401

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            +P G  + I  + +HR P  +PNP  FDP+ F  E    RH YA++PFSAGPR+C+G+K
Sbjct: 402 VLPEGANVGIFAFIMHRDPKYFPNPEVFDPERFSAENCKKRHPYAYLPFSAGPRNCIGQK 461

Query: 502 YAMLKLKVILSTILRNFRVISDLKE-SDFKLQADIILKRAEGFQVRLQPR 550
           +AM++LKV+LSTILR  ++ S   E S   L   I+LK  +  ++++  R
Sbjct: 462 FAMMELKVVLSTILRFAKIESVNDEISARSLTPLILLKPCDPIRIKVFSR 511



 Score =  124 bits (299), Expect = 6e-27
 Identities = 63/202 (31%), Positives = 112/202 (55%), Gaps = 2/202 (0%)

Query: 84  DHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWR 143
           ++  +V  W+     V+L+DP D+EVIL+S   I K  EY    PW+ +GL++S G+KW 
Sbjct: 73  EYARLVAFWLAGIPTVWLFDPDDLEVILASSQAIQKGNEYHCLFPWMQDGLVLSKGEKWH 132

Query: 144 SHRKLIAPTFHLNVLKSFIDLFNANSRAVV-DKLKKEASNFDCHDYMSECTVEILLETAM 202
             RKL+ P FH  +L++ +   N N+R ++ + LKKE   F   + +  CT++++ ETAM
Sbjct: 133 QRRKLLTPAFHFKILENNMQSLNKNARCLLRNMLKKEGRPFVTQELVVRCTLDVISETAM 192

Query: 203 GVSKSTQD-QSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261
           G + + Q+ +   +Y  AV + C +   R   ++   D ++  T   +  +K L  +H  
Sbjct: 193 GHALNLQEREENNDYLNAVERACSLTFDRSKNVFYSNDGVYFLTLDGRKFSKNLKYLHNF 252

Query: 262 TKKVIKRKKEEFASGKKPSNLN 283
           ++ +I+ +K ++   KK S  N
Sbjct: 253 SENIIQNRKLKYLLEKKYSENN 274


>UniRef50_UPI0000D5646A Cluster: PREDICTED: similar to CYtochrome
           P450 family member (cyp-31A3); n=2; Tribolium
           castaneum|Rep: PREDICTED: similar to CYtochrome P450
           family member (cyp-31A3) - Tribolium castaneum
          Length = 349

 Score =  191 bits (466), Expect = 4e-47
 Identities = 95/231 (41%), Positives = 149/231 (64%), Gaps = 6/231 (2%)

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           ++KRL  L+ LL+ S+    I    +++++ TI+  G +TTA      L ++GI+ +IQ 
Sbjct: 123 REKRL--LNHLLKLSKINAKIDQTALEDEIQTILLTGSETTALTVGLTLIILGIYPEIQK 180

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           K+ +ELD IFG  DR  T +D   M+YLER + ETLR   PVP + R  NQ+ITL SN  
Sbjct: 181 KIGKELDVIFGKDDRVPTLEDINRMEYLERVIKETLRFLTPVPFMLRTNNQDITLDSN-- 238

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            IPAG+ ++I  + +H++P+ + NPN+FDPD FLPE S+ R   AF+PFS+GPR+C+G K
Sbjct: 239 TIPAGSCIMIPIFHIHKKPEYWKNPNEFDPDRFLPENSSKRPRCAFIPFSSGPRNCIGFK 298

Query: 502 YAMLKLKVILSTILRNFRVISD--LKESDFKLQADIILKRAEGFQVRLQPR 550
           Y M+ +KV+L+ ILR + V++    K  D ++   ++ K   G +++L+ +
Sbjct: 299 YGMMSVKVLLAVILRKYTVVATEYKKVEDIEMLFYVVNKPISGCKIKLEKK 349



 Score = 42.7 bits (96), Expect = 0.025
 Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 5/73 (6%)

Query: 128 PWLGNGLLISTGQK---WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SN 182
           P  G+   +  G K   W+S RK+I PTF+ N+L SF+++F  ++  + + L++     +
Sbjct: 43  PIFGSAHYLMGGHKVDVWKSRRKMINPTFNPNILNSFVEIFGRHAFYLTNALEENCGKDS 102

Query: 183 FDCHDYMSECTVE 195
           FD    +  CT +
Sbjct: 103 FDILPKLFRCTFD 115


>UniRef50_Q9VS79 Cluster: Cytochrome P450 4d8; n=6; Schizophora|Rep:
           Cytochrome P450 4d8 - Drosophila melanogaster (Fruit
           fly)
          Length = 463

 Score =  190 bits (464), Expect = 6e-47
 Identities = 93/235 (39%), Positives = 156/235 (66%), Gaps = 8/235 (3%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G K+R+A LD+LL S+  G  ++++EI+E+VDT MFEGHDTT +  SF L  +  H ++Q
Sbjct: 231 GSKRRMALLDVLLMSTVDGRPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQ 290

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIAR--QVNQEITLP 437
            K++EE+ Q+ G D  RPV+ +D  E+KY+E  + E+LR+YPPVPI+ R  Q + + T  
Sbjct: 291 AKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHS 350

Query: 438 SNGK-KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496
            +G   IPAG+ ++I  + +HR+P+ +PNP++F P+    E  +    +  +PFSAGPR+
Sbjct: 351 VHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH--ENGSRVAPFKMIPFSAGPRN 408

Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           C+G+K+A L++K++L+ I+R + ++        +   +I+L+   GFQ+ ++ RK
Sbjct: 409 CIGQKFAQLEMKMMLAKIVREYELLP--MGQRVECIVNIVLRSETGFQLGMRKRK 461



 Score =  120 bits (288), Expect = 1e-25
 Identities = 72/224 (32%), Positives = 119/224 (53%), Gaps = 6/224 (2%)

Query: 90  KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149
           ++WI  RLL+   D    E +LSS  ++ K   Y+    WLGNGLL+S G+ W   RK+I
Sbjct: 28  RVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRRKII 87

Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SNFDCHDYMSECTVEILLETAMGVSKS 207
            PTFH ++L+ F+++F+  S   V +L ++A  + FD +  +    ++I+ ETAMG    
Sbjct: 88  TPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIAETAMGTKIY 147

Query: 208 TQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFT-DYAK-NQTKLLDIIHGLTKKV 265
            Q      YA AV +   +L  R   ++L+ +LLF  T  + K  QT+L+  +   T KV
Sbjct: 148 AQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTIKV 207

Query: 266 IKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSG 309
           I+++++  A   + S L +TA     S  ++  ++ L      G
Sbjct: 208 IEKRRQ--ALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDG 249


>UniRef50_Q170T0 Cluster: Cytochrome P450; n=12; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 505

 Score =  190 bits (462), Expect = 1e-46
 Identities = 94/236 (39%), Positives = 152/236 (64%), Gaps = 8/236 (3%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G +K++AFLD+LL+++  G  + D E++E+VDT MFEGHDTT +  SF + ++  H D+Q
Sbjct: 274 GIRKKVAFLDMLLQATVDGRPLDDLEVREEVDTFMFEGHDTTTSAISFLIGILAKHPDVQ 333

Query: 381 DKVIEELDQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQV--NQEITLP 437
            KV +E+  + GD  +  VT     ++ YL+  + ETLRLYP VPI  R +  NQEI   
Sbjct: 334 QKVYDEVRNVIGDDLNVSVTLSMLNQLNYLDLVIKETLRLYPSVPIYGRMLLENQEI--- 390

Query: 438 SNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRS 496
            NG   PAG+ L I  Y + R P+ + NP +F P+ F  E SA + + Y +VPFSAGPR+
Sbjct: 391 -NGTVFPAGSNLAIFPYFMGRDPEYFENPLEFRPERFAVETSAEKANPYRYVPFSAGPRN 449

Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552
           C+G+K+A+ ++K ++S ++R++ V+   + +  ++ A+++L+   G  VR++ R R
Sbjct: 450 CIGQKFAVAEIKSLISKLVRHYEVLPPKQPNSERMIAELVLRPEGGVPVRIRSRVR 505



 Score =  159 bits (387), Expect = 1e-37
 Identities = 90/262 (34%), Positives = 142/262 (54%), Gaps = 6/262 (2%)

Query: 18  INLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIV 77
           I L  V+++   +  Y Y + + R  Y  A K+          N++++   S   F   V
Sbjct: 3   ILLASVVVLSIGLAVYFYQQFANRLHY--AAKIGGPKGYPLLGNSIQYGTKSPVEFLQEV 60

Query: 78  QKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIS 137
           QK+ +   +   ++WIGP L+  + D + VE ILSS   +DK+ +Y F +PWLGNGLL S
Sbjct: 61  QKTNEQCGK-FYRLWIGPDLIFPITDAKLVEAILSSQKLLDKSVQYDFIRPWLGNGLLTS 119

Query: 138 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSECTV 194
           TG+KW S RK+I PTFH  +L+ F+++F+  S   V +LK +A    +FD    ++ C +
Sbjct: 120 TGRKWHSRRKIITPTFHFKILEQFVEIFDQQSNIFVGQLKSKAQSGEDFDVFPVVTLCAL 179

Query: 195 EILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKL 254
           +++ E+AMG   + Q  S  +Y  AV  M  +   R  K + R +  F FT Y + Q K 
Sbjct: 180 DVICESAMGTKVNAQLNSDSKYVRAVKDMATVAMARSFKAFARFNFTFYFTPYRRMQDKA 239

Query: 255 LDIIHGLTKKVIKRKKEEFASG 276
           L ++H  T  VI+ ++ E A G
Sbjct: 240 LKVLHDYTDSVIRSRRLELAKG 261


>UniRef50_Q9V7G5 Cluster: Probable cytochrome P450 4aa1; n=5;
           Diptera|Rep: Probable cytochrome P450 4aa1 - Drosophila
           melanogaster (Fruit fly)
          Length = 514

 Score =  190 bits (462), Expect = 1e-46
 Identities = 90/230 (39%), Positives = 142/230 (61%), Gaps = 2/230 (0%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G  +R   LD ++E S+S    ++E+I  +  T M  G D+  A  +F L ++  + + Q
Sbjct: 280 GNSERKCLLDHMIEISESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQ 339

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           D+ + EL  IF DS+R  T  D  EM+Y+E C+ E LRLYP VP+IAR++ +E+ L  + 
Sbjct: 340 DRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKH- 398

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             +PAG+ + I  Y  HR   +YP+P KF P+ F PE S NRH YAF+PFSAGPR C+G 
Sbjct: 399 -TLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGN 457

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           ++A++++K I+S +LR+++++    ++       I L+ + G  VRL+ R
Sbjct: 458 RFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRLKER 507



 Score =  109 bits (262), Expect = 2e-22
 Identities = 65/205 (31%), Positives = 115/205 (56%), Gaps = 6/205 (2%)

Query: 71  DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 130
           D+ R    K+ D  + S+V+IW+       + +P D++VILSS  + +K   YR    +L
Sbjct: 71  DLMRRCAGKAFDL-YGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFL 129

Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SNFDCHDY 188
           G+GL+ S+G KW +HR+LI P FH N+L+ FID F   S+++ + L  EA  +  +   Y
Sbjct: 130 GDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKY 189

Query: 189 MSECTVEILLETAMGV--SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 246
           ++ C ++IL E  +GV   K  QD +  E +    +   ++  R T+ WL  D ++ +T 
Sbjct: 190 VNNCVLDILNEAVLGVPIKKRGQDVAMMEDS-PFRQGKIMMPARFTQPWLLLDGIYHWTK 248

Query: 247 YAKNQTKLLDIIHGLTKKVIKRKKE 271
            A ++      ++  T+K+I+R+++
Sbjct: 249 MANDELNQKKRLNDFTRKMIQRRRQ 273


>UniRef50_Q8ISJ7 Cluster: Cytochrome P450 CYP4L4; n=4;
           Noctuidae|Rep: Cytochrome P450 CYP4L4 - Mamestra
           brassicae (Cabbage armyworm)
          Length = 492

 Score =  189 bits (460), Expect = 2e-46
 Identities = 90/232 (38%), Positives = 154/232 (66%), Gaps = 8/232 (3%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G K +  FLDLLL +   G  I DE ++E+VDT MFEGHDTT +G  + L  +   +D+Q
Sbjct: 268 GTKNKHTFLDLLLLAEIDGKKIDDESVREEVDTFMFEGHDTTTSGIVYTLHCLSKRRDVQ 327

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           +K+ EEL  IFG +  R  T+ +  +MKYLE  + E++RL+PPVP+I R++ ++  +   
Sbjct: 328 EKIYEELKTIFGSEIHRDPTYHELQQMKYLELVIKESMRLFPPVPLIERRIMKDCEV--G 385

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G K+  GT++V+  +++ R+PD++ +P +F P+ F    +  ++ ++++ FSAGPR+C+G
Sbjct: 386 GLKLVKGTSVVMNIFQIQRQPDLFDDPLEFRPERF---EAPLKNPFSWLAFSAGPRNCIG 442

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           +K+AM++LK+ +S I++NF ++   +E +  L AD++L+   G  V+  PRK
Sbjct: 443 QKFAMMELKITISEIVKNFFILPAAEEPE--LSADLVLRSKNGVNVKFLPRK 492



 Score =  126 bits (303), Expect = 2e-27
 Identities = 88/296 (29%), Positives = 144/296 (48%), Gaps = 17/296 (5%)

Query: 20  LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79
           +F V+++  ++ W +  R+SRR        L          NA  FV  S++ F N+VQ+
Sbjct: 6   VFVVVVLALLVSWISLVRVSRRFNVPGPSPLPLVG------NAHLFVVKSSE-FLNLVQR 58

Query: 80  -SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST 138
            S  Y H   V  +  P   V +   +  E ++SS  +I K   Y F   WLG GLL +T
Sbjct: 59  LSEKYGHAFRVHFFSTP--YVVICHSKYAEPLVSSTEHITKGRSYSFLTCWLGQGLLTAT 116

Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEI 196
           GQ+W+SHRK + P FH N+L++F+ +F  N R + +K++  A     D    ++   ++ 
Sbjct: 117 GQRWKSHRKFLTPAFHFNILQNFLPVFCKNQRILTEKIRGMADGRPIDMFPIIALAALDN 176

Query: 197 LLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLD 256
           + E+ MGV    Q  S  EY  ++ ++  I+ +R    +   D +F    Y   Q K L 
Sbjct: 177 VNESIMGVCMDAQKHSQSEYVKSIEELSAIVTMRMQIPFFGEDAIFNLLPYKTKQDKALK 236

Query: 257 IIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPST-GKLTSVEGLSFGQSSGLK 311
           ++HG T KVI  ++ E     K +N+     +S+  T  K T ++ L   +  G K
Sbjct: 237 VLHGQTNKVINARRAEL----KKANITTLNDSSDIGTKNKHTFLDLLLLAEIDGKK 288


>UniRef50_A1BPS3 Cluster: CYP4BG1; n=1; Ips paraconfusus|Rep:
           CYP4BG1 - Ips paraconfusus
          Length = 498

 Score =  188 bits (459), Expect = 3e-46
 Identities = 94/227 (41%), Positives = 137/227 (60%), Gaps = 5/227 (2%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           +K    LDLLL       +I  E I+E+VDT MFEGHDTT+A   F L  +  +  IQ+K
Sbjct: 275 RKIYKMLDLLLHEKLQFGSIDYEGIREEVDTFMFEGHDTTSAALVFLLHNLASNLAIQEK 334

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           V +E+  +    +R  TFQ    + Y +R + E+LRLYP VP I+R  +++  +   G  
Sbjct: 335 VRQEIKTV----ERIPTFQTLQNLPYTDRVIKESLRLYPSVPFISRIASEDF-ITHTGYS 389

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           I  GT L +  + LHR P++YP+P  FDPD FLPE+   RH +A++PFSAGPR+C+G+K+
Sbjct: 390 ISKGTVLYMHIFDLHRNPEIYPDPLTFDPDRFLPEKVKERHPFAYLPFSAGPRNCIGQKF 449

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549
           AML+LK +L  +L  FR+  D   +    Q D+IL+     ++  QP
Sbjct: 450 AMLELKAVLWGLLHKFRLTLDPSTTQINFQVDLILRTQGEIKINFQP 496



 Score =  118 bits (285), Expect = 3e-25
 Identities = 83/297 (27%), Positives = 150/297 (50%), Gaps = 17/297 (5%)

Query: 69  SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP 128
           S ++F  +   + DY    + +I I    +V  + P D+E+ILS   ++ K+  Y+F + 
Sbjct: 52  SGELFDQLRNFARDYG--PIYRISIPFLDIVNFFHPADLEIILSQKKHMKKSLLYQFLEG 109

Query: 129 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK------KEASN 182
           WLG GLL STG KW+  RKL+   FH N+L+ F+ +FN  +  +V +++      +  + 
Sbjct: 110 WLGKGLLTSTGSKWQFRRKLLTQAFHFNILQKFVRVFNEETTHLVKRIEEINLTGQSQAG 169

Query: 183 FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLF 242
                 ++  T++ + ET++GVS + + ++   Y   + KM D L  R  K W   + ++
Sbjct: 170 ISVLPLITHLTLQSVTETSLGVS-NIEKETLKAYRENIYKMGDFLIDRLRKPWRLFNFIY 228

Query: 243 KFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSV--- 299
            FT+ +K +   ++ +H  T +VIK ++E   S K  S +  T+T S     K+  +   
Sbjct: 229 HFTEASKQEQLTINKLHQFTYQVIKEREEVLQSDKTQSVM--TSTYSGRKIYKMLDLLLH 286

Query: 300 EGLSFG--QSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTI 354
           E L FG     G++         G     A L  LL +  S +AI  E++++++ T+
Sbjct: 287 EKLQFGSIDYEGIREEVDTFMFEGHDTTSAALVFLLHNLASNLAI-QEKVRQEIKTV 342


>UniRef50_Q16I47 Cluster: Cytochrome P450; n=7; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 506

 Score =  188 bits (457), Expect = 4e-46
 Identities = 88/230 (38%), Positives = 145/230 (63%), Gaps = 4/230 (1%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           K+++ FLDLLL  + +G  +S E+I+E+VDT MFEGHDTT +G SF L  +  +QD+Q K
Sbjct: 278 KRKMTFLDLLLNVTVNGKPLSREDIREEVDTFMFEGHDTTTSGISFTLWHLAKYQDVQQK 337

Query: 383 VIEELDQIFGDS--DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           + EE+D++ G    +  +T     E+ YL+  + E+LRL PPVPII R + +++ +  NG
Sbjct: 338 LFEEIDRVLGKDKVNAELTNLQIQELDYLDMVVKESLRLIPPVPIIGRTLVEDMEM--NG 395

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             IPAGT + I  Y +HR P ++   ++F P+ F     + R  Y F+PFSAG R+C+G+
Sbjct: 396 VTIPAGTQISIKIYNIHRNPKIWEKSDEFIPERFSKTNESKRGPYDFIPFSAGSRNCIGQ 455

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +YAM++LKV +  ++ +F+V+        + + D++++   G  ++L  R
Sbjct: 456 RYAMMELKVTIIKLIASFKVLPGDSMDKLRFKTDLVIRPDNGIPIKLVER 505



 Score =  128 bits (308), Expect = 5e-28
 Identities = 81/230 (35%), Positives = 124/230 (53%), Gaps = 9/230 (3%)

Query: 65  FVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR 124
           F+G +     +I+        E +  I     L++ L   ++VE +L +   I K+  Y 
Sbjct: 48  FIGKTIPDIWDIITDLHKKHGEDIAIIAAFNELVMDLSSSKNVEKVLLAKS-IKKSFAYD 106

Query: 125 FFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SN 182
           F +PWLG GLLISTG+KW   RK+I PTFH ++L+ F+++FN  +  +V KLK +A    
Sbjct: 107 FLEPWLGTGLLISTGEKWFQRRKIITPTFHFSMLEGFLEVFNKEANILVSKLKAKAGKDE 166

Query: 183 FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLR--PDL 240
           FD +DY++   ++ + ET+MGV  + QD    EYA+AV +M   + LR     LR  P L
Sbjct: 167 FDIYDYVTLYALDSICETSMGVQINAQDDPNNEYAVAVKQMSTFI-LRRVFSILRTFPSL 225

Query: 241 LFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSE 290
            F +  +AK Q K++  +H  T  VI  ++      K+ SN N T    E
Sbjct: 226 FFLY-PFAKEQKKVILKLHNFTNSVIDARRAMLE--KEKSNKNVTFDLQE 272


>UniRef50_Q9VMS9 Cluster: Probable cytochrome P450 4ac1; n=5;
           Sophophora|Rep: Probable cytochrome P450 4ac1 -
           Drosophila melanogaster (Fruit fly)
          Length = 509

 Score =  187 bits (455), Expect = 8e-46
 Identities = 93/230 (40%), Positives = 145/230 (63%), Gaps = 4/230 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G+K+R A LD LL +   G  I  + I ++V+T MFEG+DTT+    F L M+ +H+D+Q
Sbjct: 282 GRKQRYAMLDTLLAAEADG-QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQ 340

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
            K  EE++ +  DSD    FQ   ++ YLE  + E+LR++P VP I RQ  +E  +  NG
Sbjct: 341 KKCYEEVENLPEDSDDISMFQFN-KLVYLECVIKESLRMFPSVPFIGRQCVEETVV--NG 397

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             +P  T + I  Y + R P  +P P+ F PD FLPE + NRH +A+VPFSAG R+C+G+
Sbjct: 398 MVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNRHPFAYVPFSAGQRNCIGQ 457

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           K+A+L++KV+L+ ++RNF+++   +  D   +  I+L+  E  +V+L  R
Sbjct: 458 KFAILEMKVLLAAVIRNFKLLPATQLEDLTFENGIVLRTQENIKVKLSKR 507



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 55/172 (31%), Positives = 92/172 (53%), Gaps = 4/172 (2%)

Query: 104 PRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFID 163
           P + E +  S   I K   Y   +P+LG+GLLIST  KW S RK + P FH NVL+SF+ 
Sbjct: 101 PEEAEEVFQSTKLITKNVVYELIRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLG 160

Query: 164 LFNANSRAVVDKLKKEA-SNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMK 222
           +F    +  ++ L+K   +  + +  +   T+  + ETA+GV K      G EY  A+  
Sbjct: 161 IFKEECKKFLNVLEKNLDAELELNQVIPPFTLNNICETALGV-KLDDMSEGNEYRKAIHA 219

Query: 223 MCDILHLRHTKIWLRPD-LLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEF 273
           + ++L  R     +  +   F + DY K+  + L I+H  + ++I+RK+++F
Sbjct: 220 IEEVLIQRVCNPLMYYNWYFFVYGDYRKH-LQNLRIVHDFSSRIIERKRQQF 270


>UniRef50_P33269 Cluster: Cytochrome P450 4d1; n=11; Diptera|Rep:
           Cytochrome P450 4d1 - Drosophila melanogaster (Fruit
           fly)
          Length = 512

 Score =  186 bits (454), Expect = 1e-45
 Identities = 92/234 (39%), Positives = 153/234 (65%), Gaps = 7/234 (2%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G K+++AFLD+LL+S+     +S+ +I+E+VDT MFEGHDTT++   FF   +  H + Q
Sbjct: 280 GAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQ 339

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
            K  EE+  + G D   PV+++   ++ Y++ C+ ETLR+YP VP++ R+V ++  +  N
Sbjct: 340 KKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEI--N 397

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCV 498
           GK IPAGT + I+   L RR +++  PN F P+ F    +A + + YA++PFSAGPR+C+
Sbjct: 398 GKLIPAGTNIGISPLYLGRREELFSEPNSFKPERFDVVTTAEKLNPYAYIPFSAGPRNCI 457

Query: 499 GRKYAMLKLKVILSTILRNFRV--ISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           G+K+AML++K I++ +LR++ V  + D  E    L A++IL+  E    +++ R
Sbjct: 458 GQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPV-LIAELILRTKEPLMFKVRER 510



 Score =  171 bits (416), Expect = 4e-41
 Identities = 88/270 (32%), Positives = 148/270 (54%), Gaps = 7/270 (2%)

Query: 24  LLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSA-DIFRNIVQKSAD 82
           +L  A+ +    + +  +RL +L   +          +   F+G    ++ + I +    
Sbjct: 8   ILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMET 67

Query: 83  YDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKW 142
           Y  + V+K+W+GP L V + +P+DVEV+L +  + DKA EY+  +PWL  GLL+S G+KW
Sbjct: 68  YSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKW 127

Query: 143 RSHRKLIAPTFHLNVLKSFIDLFNANSRAVV-----DKLKKEASNFDCHDYMSECTVEIL 197
              RK+I P FH  +L  F+++F   SR ++     D+LK   S F  +D+++ CT++ +
Sbjct: 128 HKRRKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGESGFSLYDWINLCTMDTI 187

Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257
            ETAMGVS + Q  +  EY  AV  +  +LH R   I  R DL +  T  A+ + K L++
Sbjct: 188 CETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEKKALNV 247

Query: 258 IHGLTKKVIKRKKEE-FASGKKPSNLNETA 286
           +H  T+K+I +++EE    G    + N+ A
Sbjct: 248 LHQFTEKIIVQRREELIREGSSQESSNDDA 277


>UniRef50_Q9XVA6 Cluster: Putative uncharacterized protein cyp-37A1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein cyp-37A1 - Caenorhabditis elegans
          Length = 508

 Score =  186 bits (453), Expect = 1e-45
 Identities = 89/231 (38%), Positives = 146/231 (63%), Gaps = 3/231 (1%)

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           + K+ AFLD+L+E  + G  +  E+I+E+VDT MFEGHDTT+AG  + L  +    + Q 
Sbjct: 281 ESKKKAFLDMLIEKKEEG-GLGYEDIREEVDTFMFEGHDTTSAGIGWSLWCLANCPEYQK 339

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           K  EELD+IF  + R  + +D  +MKYLE+C+ E LR+ P VP +AR V +E+ +  +GK
Sbjct: 340 KCHEELDEIFEGTSRECSVEDLKKMKYLEKCVKEALRMRPSVPQMARSVEEEVEI--DGK 397

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            +P G +++I+   +   P  +PN   FDP+ F  +  + RH YA++PFSAGPR+C+G+K
Sbjct: 398 ILPKGCSVMISPAFIQNNPRTFPNHEVFDPERFNEDEISKRHAYAYIPFSAGPRNCIGQK 457

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552
           +AM + K ++S +LR F + +D+   +     + I + + GF ++   R++
Sbjct: 458 FAMQEEKTVISWVLRRFHIHTDIGLLENMPLPETITRPSLGFPLKFTVRQQ 508



 Score =  138 bits (334), Expect = 4e-31
 Identities = 82/265 (30%), Positives = 135/265 (50%), Gaps = 14/265 (5%)

Query: 17  AINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNI 76
           A+ + YV+   + IL +   RM   RLY L  K++            +F     +    +
Sbjct: 9   ALVVIYVVFNLSKILKFVKERM---RLYHLMSKIDGPLALPLLGTTFQFKMDPVEFALQL 65

Query: 77  VQKSADYDHE--SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGL 134
                +Y  +  S+   W+GP  +V +  P   + +L S+  I+K+ EY  F PWLG GL
Sbjct: 66  YNWGLEYSTKGSSLAAFWMGPYPMVIVLTPEANKKVLESNALINKSSEYDIFLPWLGTGL 125

Query: 135 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKL-----KKEASNFDCHDYM 189
           L+++G+KWR  RK++ P+FH NVL  F  +FN+ S  +++++     K + S  D   Y+
Sbjct: 126 LLASGEKWRGRRKMMTPSFHFNVLIDFQVVFNSQSMILLEQIENAAKKTDDSTIDAFPYI 185

Query: 190 SECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDIL--HLRHTKIWLRPDLLFKFTDY 247
             C ++I+ ETAMG + S Q      Y +AV +M  +   + R   +W++P  + +   Y
Sbjct: 186 KRCALDIICETAMGTTVSAQTNHTHPYVVAVNEMNSLAFKYQRMPWLWIKP--IRQLIGY 243

Query: 248 AKNQTKLLDIIHGLTKKVIKRKKEE 272
             +  + LDI+   TKKVI RK  E
Sbjct: 244 EADFQRNLDIVTSFTKKVIDRKLRE 268


>UniRef50_Q4R1I7 Cluster: Cytochrome P450; n=1; Papilio xuthus|Rep:
           Cytochrome P450 - Papilio xuthus
          Length = 506

 Score =  186 bits (453), Expect = 1e-45
 Identities = 88/230 (38%), Positives = 148/230 (64%), Gaps = 4/230 (1%)

Query: 324 KRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383
           K  +FLDLL+E S      +D E++E++ T+   G DTT     + L ++ ++  +QDK+
Sbjct: 276 KTQSFLDLLIEFSGGENGYTDLELREEILTLTIAGTDTTGISIGYTLKLLAMYPKVQDKL 335

Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443
            +EL  +FG SDR +  +D  ++KYLER + E+LRLYPP P I R+V ++I+LPS G+  
Sbjct: 336 YQELLDVFGTSDRRIVKEDLSKLKYLERIVKESLRLYPPGPFIIRKVLEDISLPS-GRVF 394

Query: 444 PAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           PAG+   ++ + LHR P  + P+   FDPD FLPER   +H  +++PFS+GPR+C+G +Y
Sbjct: 395 PAGSGAAVSIWGLHRDPKYWGPDAEVFDPDRFLPERFNLKHACSYIPFSSGPRNCIGYQY 454

Query: 503 AMLKLKVILSTILRNFRVISDLK--ESDFKLQADIILKRAEGFQVRLQPR 550
           A++ +K +LS I+R ++++ +        K + DI++K  + +++ L+ R
Sbjct: 455 ALMSMKTVLSAIVRRYKIMGEESGPVPHIKSKIDIMMKAVDDYKICLEKR 504



 Score =  127 bits (307), Expect = 7e-28
 Identities = 75/262 (28%), Positives = 133/262 (50%), Gaps = 6/262 (2%)

Query: 20  LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXN-ALEFVGGSADIFRNIVQ 78
           +F  LL  +V+L    +++ RRRLY LA K+            A +F G + DI  ++ +
Sbjct: 1   MFLCLLCLSVVLGMVLFKLKRRRLYRLASKIPGSDDELPFIGLAHKFTGTTEDILNSLQK 60

Query: 79  KSAD-YDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIS 137
            S +   +  +++ W+G  L   + DP DVEVIL +   ++K + +RF +  +GNGL+ +
Sbjct: 61  YSYEAMKNNGILRGWLGHILYFIVVDPVDVEVILKTS--LEKDDLHRFIRNVIGNGLIFA 118

Query: 138 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVE 195
               WR  RK+  P F   ++ +F+++F   S  +V  L   A N       Y+   T++
Sbjct: 119 PVSIWRRRRKITVPAFSPKIVDTFMEVFAEQSEKLVSVLAACAGNGYIAMEPYLCRYTLD 178

Query: 196 ILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLL 255
            + ET MG++ + Q+     Y  A+  + +++  R   +WL+PD L+KF   +K+  K  
Sbjct: 179 SVCETTMGITTNAQNNPNAPYLKALKNILNLVCERIFHLWLQPDWLYKFFSQSKSHQKYT 238

Query: 256 DIIHGLTKKVIKRKKEEFASGK 277
             + G   +VI+ K+ E    K
Sbjct: 239 KEMQGFVDEVIQNKRREIKKEK 260


>UniRef50_A1BPR9 Cluster: CYP4BD1; n=1; Ips paraconfusus|Rep:
           CYP4BD1 - Ips paraconfusus
          Length = 504

 Score =  186 bits (452), Expect = 2e-45
 Identities = 91/232 (39%), Positives = 143/232 (61%), Gaps = 4/232 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G + RLAFLDLLLE+   G  ++  E++++V+T MFEGHDTT++  +F L M+  H  +Q
Sbjct: 275 GIRTRLAFLDLLLEAKIDGTPLTKAELRDEVNTFMFEGHDTTSSAITFCLLMLATHPRVQ 334

Query: 381 DKVIEELDQIF-GDSDRP-VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438
           DKV+ E  +I  GD      T ++  +MKYLE  + ETLRLYP VP+ +R++ +++    
Sbjct: 335 DKVMAEQKEILEGDLKLAHPTSKELSQMKYLENVIKETLRLYPSVPLFSRKLGEDVEF-- 392

Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
            G   P G TLV+  Y  HR PD++P P KF P+ F        + +A+ PFSAG R+C+
Sbjct: 393 KGNLYPKGITLVLTPYATHRDPDIFPEPEKFLPERFEESEMLKINPFAYTPFSAGSRNCI 452

Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           G+K+AM+++K  +S ++R+F++     E   +L ++  L    G ++ LQ R
Sbjct: 453 GQKFAMMEIKSTVSKVVRHFKLEPAHPEHQIQLVSETTLNSKNGVKISLQAR 504



 Score =  118 bits (285), Expect = 3e-25
 Identities = 73/218 (33%), Positives = 116/218 (53%), Gaps = 10/218 (4%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGP-RLLVFLYDPRDVEVILSSHVYIDK 119
           N L F+ GS      I+Q   +    S+     GP   +V   DP  +E+I SS  +I K
Sbjct: 47  NTLPFLKGSVVYLDLIMQGVKELGRTSLFHD--GPLSWVVITADPEFIELIYSSSTHITK 104

Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE 179
             +Y +FK WLG GLLIS G KWR HRK+I PTFH ++L+ F+ +F+      V KL++ 
Sbjct: 105 GSQYDYFKRWLGQGLLISDGDKWRFHRKIITPTFHFSILQQFLTVFDTVGDNFVRKLQQH 164

Query: 180 --ASNFDCHDYMSECTVEILLETAMGVSKST---QDQSGFEYAMAVMKMCDILHLRHTKI 234
             +++ +  + +S CT++I+ ETAMGV  +    +D    EY   +  MC I+  R    
Sbjct: 165 VGSTSVEISNLISLCTLDIICETAMGVKMNALDMKDSENMEYIKGIRIMCKIIVDRMFS- 223

Query: 235 WLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272
           +L P + +  T     + + L +++G    VI +K ++
Sbjct: 224 FLHP-IFYPLTLNYYREKRALKMVNGYVDNVISQKIQQ 260


>UniRef50_Q9VXY0 Cluster: Probable cytochrome P450 4s3; n=5;
           Acalyptratae|Rep: Probable cytochrome P450 4s3 -
           Drosophila melanogaster (Fruit fly)
          Length = 495

 Score =  186 bits (452), Expect = 2e-45
 Identities = 96/232 (41%), Positives = 146/232 (62%), Gaps = 15/232 (6%)

Query: 321 GQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           G K+RLAFLD LLL   + G  +SD +I+E+VDT MFEGHDTT++  +F LS++  + D+
Sbjct: 270 GAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDV 329

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q +  EE  ++ G        ++   M YLE  + ETLR+YP VP  +R+V +++ +   
Sbjct: 330 QQRAFEEASELEG--------REKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEV--- 378

Query: 440 GK-KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
           GK  +P G ++    Y LHR P  +P+P +FDPD FL       H +AF  FSAGPR+C+
Sbjct: 379 GKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNEK-QMHPFAFAAFSAGPRNCI 437

Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           G+K+AML+LK  L+ +LR++R + D K+   K  A+++ K   G ++R+ PR
Sbjct: 438 GQKFAMLELKTSLAMLLRSYRFLPD-KDHQPKPLAELVTKSGNGIRLRILPR 488



 Score =  145 bits (351), Expect = 3e-33
 Identities = 65/190 (34%), Positives = 107/190 (56%), Gaps = 2/190 (1%)

Query: 85  HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144
           H  V +IW G  L+V   DP D++ +L ++  + K+  Y   +PWLG GLL + G+ W  
Sbjct: 63  HGPVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYELLEPWLGKGLLTNGGESWHR 122

Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS--NFDCHDYMSECTVEILLETAM 202
            RKL+ P FH  +L  F +    N R +V +L+ +A+  +FD + Y++   ++ + ETAM
Sbjct: 123 RRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAM 182

Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262
           G+ K  Q QS  EY  AV  +C ++H +    W R ++ FK T   K +   L ++H  T
Sbjct: 183 GIKKHAQLQSDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDET 242

Query: 263 KKVIKRKKEE 272
            +VI+ ++E+
Sbjct: 243 NRVIRLRREQ 252


>UniRef50_UPI0000D9991B Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily A, polypeptide 11 isoform 1;
           n=3; Catarrhini|Rep: PREDICTED: similar to cytochrome
           P450, family 4, subfamily A, polypeptide 11 isoform 1 -
           Macaca mulatta
          Length = 487

 Score =  184 bits (448), Expect = 5e-45
 Identities = 91/228 (39%), Positives = 142/228 (62%), Gaps = 6/228 (2%)

Query: 322 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           +KK L FLD LLL   ++G  +SD++++ +VDT MFEGHDTTA+G S+ L  +  H   Q
Sbjct: 253 RKKHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 312

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           ++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I+R+++  +T P +G
Sbjct: 313 ERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGISRELSTPVTFP-DG 370

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
           + +P G T++++ Y LH  P V+PNP  FDP  F P   + +H +AF+PFS G R+C+G+
Sbjct: 371 RSLPKGITVMLSIYGLHHNPKVWPNPEVFDPSRFAP--GSAQHSHAFLPFSGGSRNCIGK 428

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548
           ++AM +LKV  +  L  F ++ D       + A ++LK   G  +RL+
Sbjct: 429 QFAMNELKVATALTLLRFELLPDPTRIPIPM-ARLVLKSKNGIHLRLR 475



 Score = 79.4 bits (187), Expect = 2e-13
 Identities = 54/179 (30%), Positives = 91/179 (50%), Gaps = 9/179 (5%)

Query: 87  SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 145
           S   +W+ G +  V L+DP  ++VIL       + + YRF  PW+G GLL+  GQ W  H
Sbjct: 84  SACPLWLWGGKARVQLHDPDYMKVILGRSDPKSQ-DPYRFLAPWIGYGLLLLNGQTWFQH 142

Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAM 202
           R+++ P FH ++LK+++ L   + R ++DK +K   + S  +   ++S  T++ +++ A 
Sbjct: 143 RRMLTPAFHYDILKAYVALMADSVRVMLDKWEKLLGQDSPLEVFQHVSLMTLDTIMKCAF 202

Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTK--IWLRPDLLFKFTDYAK-NQTKLLDII 258
               S Q  S         + C + H +HT   I LR   L K  +  K  + K LD +
Sbjct: 203 SHQGSIQVDSLTSTGRWTHRACQLAH-QHTDQVIQLRKAQLQKEGELEKVKRKKHLDFL 260


>UniRef50_A1BPS5 Cluster: CYP4BJ1; n=1; Ips paraconfusus|Rep:
           CYP4BJ1 - Ips paraconfusus
          Length = 464

 Score =  184 bits (448), Expect = 5e-45
 Identities = 86/181 (47%), Positives = 124/181 (68%), Gaps = 3/181 (1%)

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           +KKRLAFLDLLL+       ++DE+I+E+VDT MFEGHDT ++   FF+  M     +Q+
Sbjct: 285 EKKRLAFLDLLLDLQYETGRLNDEDIREEVDTFMFEGHDTVSSSMGFFVFSMSQRLHLQE 344

Query: 382 KVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           KV EE+ +IFG D +R VT +D  +MKYLE+C+ E +RL P VPII R ++++  +   G
Sbjct: 345 KVYEEMLEIFGNDEERDVTSEDISQMKYLEQCIREVMRLLPTVPIIGRIISEDTNI--GG 402

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             +P  TT +IA + + R    Y NP+ FDPD+F PER   R+ +A++PFSAGPR+C+G+
Sbjct: 403 YMVPKNTTAMIAPFAVQRDKRFYHNPDAFDPDHFTPERVKQRNPFAYIPFSAGPRNCIGQ 462

Query: 501 K 501
           K
Sbjct: 463 K 463



 Score =  117 bits (282), Expect = 7e-25
 Identities = 49/131 (37%), Positives = 81/131 (61%), Gaps = 3/131 (2%)

Query: 82  DYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQK 141
           D D   ++++WIGP+ LVF+Y P   +VIL S   I K  EY   + WLG GLL STG+K
Sbjct: 75  DIDSSGIMRVWIGPKPLVFIYKPETAKVILESQTLITKPGEYGILERWLGTGLLTSTGEK 134

Query: 142 WRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILL 198
           W + RK++ PTFH ++L +F+ +FN  +  +++ L + A++   FD +  +    ++++ 
Sbjct: 135 WHTRRKMLTPTFHFSILNNFMKVFNRQANTLIENLDRHAADGYPFDFYKVIKALALDVIC 194

Query: 199 ETAMGVSKSTQ 209
           E AMG++   Q
Sbjct: 195 EAAMGMNIGAQ 205


>UniRef50_A6Y7S1 Cluster: Female neotenic-specific protein 4; n=1;
           Cryptotermes secundus|Rep: Female neotenic-specific
           protein 4 - Cryptotermes secundus
          Length = 271

 Score =  184 bits (447), Expect = 7e-45
 Identities = 82/199 (41%), Positives = 128/199 (64%), Gaps = 2/199 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G++ R+  LD+L+E S++       +++E++  ++   ++TTA   SF   M+  HQD+Q
Sbjct: 65  GRRARIPILDMLIELSRNDKDYGRLDVREEIAAMLIVSYETTAVALSFACWMLSQHQDVQ 124

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           +KV+ E  +IFGDSDRP T++D  EMKYLE  + ET+RLYP +P+  R++ ++  +    
Sbjct: 125 EKVLMEQKEIFGDSDRPATYRDIQEMKYLEMVIRETIRLYPSLPVFGRKLQRDFDV--GD 182

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             IPAG  ++   Y++HR P  +P+P KF+PD FLP+    R  Y ++ FSAGPR+CVG 
Sbjct: 183 FVIPAGANVMFLAYQIHRNPKYFPDPEKFNPDRFLPDNVMRRSPYCYLAFSAGPRNCVGI 242

Query: 501 KYAMLKLKVILSTILRNFR 519
           KY M  +K  LS ++R FR
Sbjct: 243 KYGMQAIKGTLSAMIRKFR 261


>UniRef50_A1BPS4 Cluster: CYP4BH1; n=1; Ips paraconfusus|Rep:
           CYP4BH1 - Ips paraconfusus
          Length = 499

 Score =  183 bits (446), Expect = 1e-44
 Identities = 88/230 (38%), Positives = 142/230 (61%), Gaps = 4/230 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G+K+++AFLDLLL ++  G   + EEI+ +VDT MF GHDTT++  S    ++     IQ
Sbjct: 272 GRKRKMAFLDLLLSTNIDGRPPTQEEIRCEVDTFMFAGHDTTSSAMSSAFYVLAKKTQIQ 331

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
             V +EL  +FG D    +T +   E+KYLE  + E LRLYPP  +I+R   +++   ++
Sbjct: 332 KMVRDELQGVFGKDGSTQITHKSLQELKYLELFIKEVLRLYPPATVISRVTEEDVQYKNH 391

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
              IP  T + +  Y  +R PD + N  +F P+ FL + S  +  +A++PFSAGPR+C+G
Sbjct: 392 --TIPKNTLIEMLIYSANRDPDYHENAEEFKPERFL-DTSGKKRPFAYIPFSAGPRNCIG 448

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549
           +K+AML++K I+S +L NF V+  + E +  +  +++LK   G  V+L+P
Sbjct: 449 QKFAMLEMKTIISKVLMNFEVLPSIPEREMVMTTEVVLKAKNGVHVQLKP 498



 Score =  149 bits (361), Expect = 2e-34
 Identities = 64/169 (37%), Positives = 109/169 (64%), Gaps = 3/169 (1%)

Query: 107 VEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFN 166
           ++++LSS+  + K  +YR   PWLG GLL S G +W+SHRK+I P FH ++L+ F+D+FN
Sbjct: 90  LDLVLSSNKILTKGGDYRTTAPWLGQGLLTSNGLQWKSHRKMITPAFHFSILEQFVDIFN 149

Query: 167 ANSRAVVDKLKKEA---SNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 223
           +    +V+KL+++A   ++ D + Y++ C ++I+ ETAMGV+ ++Q+    EY  AV  M
Sbjct: 150 SQGDTLVNKLQRDALEKTSIDIYQYVTACALDIICETAMGVNLNSQENHDLEYVQAVKDM 209

Query: 224 CDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272
           C I+  R   +W   D L+  +   K Q ++L+I+H  T  VI ++++E
Sbjct: 210 CRIIMDRTFSLWKSFDCLYNLSKLGKKQEQVLEILHNFTNSVINKRRKE 258


>UniRef50_Q16TD6 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 519

 Score =  183 bits (445), Expect = 1e-44
 Identities = 133/471 (28%), Positives = 219/471 (46%), Gaps = 39/471 (8%)

Query: 86  ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST-GQKWRS 144
           + + K+  GP  ++ +  P  ++ ++      DK   Y +    LG GL+    G+ WR 
Sbjct: 69  DRLAKLRFGPIPVLLVNHPELIQQLMIRPELYDKPFFYEYMG--LGKGLITEQRGEIWRR 126

Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETA 201
            RKL+ P F   +L  F+ + ++ +R +V  L     + + FD     ++CT+E++  T 
Sbjct: 127 SRKLLNPAFSTRILNEFVPIMDSRARKMVKSLAVLADDKTEFDILPITAQCTLEMVFSTT 186

Query: 202 MGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGL 261
           MG  K  +     EY   +  +   +  R   I      +++FT   +      D  +G 
Sbjct: 187 MGC-KMEERPGEREYVRCLEGLMTCIGERILNIDRYLGPVYRFTKAYQVDKVCRDTCNGF 245

Query: 262 TKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXG 321
           T+K+I+ +K E A      N+N        S  ++                        G
Sbjct: 246 TEKIIQERKREMA------NINNNIIDERMSAAEIDD----------------------G 277

Query: 322 QKKRLAFLDLLLESSQ-SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           + K + FLD +L   +  G    D+E+ + + +I+  G++T+    S+    + +   IQ
Sbjct: 278 RVKSMNFLDQILTIQRPDGTNFVDDEVSDHLYSIVGAGNETSTLTISYTCLFLAMDHQIQ 337

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
            KV  E+ Q+F      VT +   ++ Y E  L ETLRL P VP  AR   + I L  +G
Sbjct: 338 AKVCSEIKQVFPSHHTEVTPEALKQLIYTEMALKETLRLCPAVPFAARSNVKPIEL--DG 395

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPN-PNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
             IP         + LHRR D + + P +FDP+ F PE S NRH YA++PFS G R+C+G
Sbjct: 396 IHIPQRQIFCFNFFALHRRKDFWGDEPEQFDPNRFSPENSRNRHPYAYLPFSGGFRNCIG 455

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
            +YA+  LK++L  IL+NF + + LK  D + +  I +K      VRL  R
Sbjct: 456 GRYAINSLKIMLLRILQNFHMDTSLKREDMRFRWAITMKLVGPHAVRLTKR 506


>UniRef50_P13584 Cluster: Cytochrome P450 4B1; n=32;
           Euteleostomi|Rep: Cytochrome P450 4B1 - Homo sapiens
           (Human)
          Length = 511

 Score =  182 bits (444), Expect = 2e-44
 Identities = 88/228 (38%), Positives = 143/228 (62%), Gaps = 4/228 (1%)

Query: 323 KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGHDTT +G S+FL  M ++ + Q 
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 339

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +G+
Sbjct: 340 RCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV-DGR 397

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            +PAG+ + +  Y LHR   V+P+P  FD   F  E ++ RH +AF+PFSAGPR+C+G++
Sbjct: 398 SLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQ 457

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549
           +AM ++KV+ +  L  F    D      K+   ++L+   GF + L+P
Sbjct: 458 FAMSEMKVVTAMCLLRFEFSLDPSRLPIKM-PQLVLRSKNGFHLHLKP 504



 Score = 83.8 bits (198), Expect = 1e-14
 Identities = 48/185 (25%), Positives = 88/185 (47%), Gaps = 7/185 (3%)

Query: 91  IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 148
           +W G  +  + +Y+P   + + S      KA + Y FF  W+G GLL+  G KW  HRKL
Sbjct: 83  LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 205
           + P FH +VLK ++ +F  ++R ++DK +   +E  +FD    +    +  L++   G  
Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200

Query: 206 KSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKV 265
            +        Y +AV  +  ++  R        D ++  T + +   +   + H  T +V
Sbjct: 201 DTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQV 260

Query: 266 IKRKK 270
           I+ +K
Sbjct: 261 IRERK 265


>UniRef50_UPI00015B61D7 Cluster: PREDICTED: similar to Cytochrome
           P450, partial; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to Cytochrome P450, partial - Nasonia
           vitripennis
          Length = 342

 Score =  180 bits (439), Expect = 7e-44
 Identities = 88/201 (43%), Positives = 131/201 (65%), Gaps = 3/201 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           G++K   FLD L++ S++    +S EEI+EQVDT MF GHDTT    S+ L  +G   ++
Sbjct: 119 GKRKPKVFLDRLMDLSEADENPLSLEEIREQVDTFMFGGHDTTGITISWVLFSLGNAPEV 178

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q KV EELD + G  ++P T +   ++KYL+R + ETLR+YP  P++ R ++    +  +
Sbjct: 179 QRKVHEELDNVIGIGNQPATKEQLSQLKYLDRVIKETLRIYPSAPMVGRILDHNTVI--D 236

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G  IP G  + +    LHR P+++  P+KF+PD FLPE S  RH YA+VPFSAGPR+C+G
Sbjct: 237 GHIIPKGVVVNLQILHLHRDPEIWDAPDKFNPDRFLPESSNGRHPYAYVPFSAGPRNCIG 296

Query: 500 RKYAMLKLKVILSTILRNFRV 520
           +K+A L LK+ L+ I+  + V
Sbjct: 297 QKFAGLVLKIALTAIMIKWEV 317



 Score = 61.3 bits (142), Expect = 7e-08
 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 9/111 (8%)

Query: 108 EVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSF------ 161
           +VIL S     K+  Y FF  WLGNGLL S+G  W  +R+L+ P FH ++L  F      
Sbjct: 3   QVILKSQTLTRKSNIYEFFAYWLGNGLLTSSGDVWHRNRRLMTPAFHFSMLDQFSEIITE 62

Query: 162 -IDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVSKSTQDQ 211
            ++LFN   +  VDK  +   N        + T++   +  MGV  +   Q
Sbjct: 63  KVELFNNCIKMEVDKNPEAPINI--FPMAIKFTLDTTCKPVMGVDMAYNPQ 111


>UniRef50_Q02928 Cluster: Cytochrome P450 4A11 precursor; n=114;
           Tetrapoda|Rep: Cytochrome P450 4A11 precursor - Homo
           sapiens (Human)
          Length = 519

 Score =  180 bits (437), Expect = 1e-43
 Identities = 89/228 (39%), Positives = 140/228 (61%), Gaps = 6/228 (2%)

Query: 322 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGHDTTA+G S+ L  +  H   Q
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           ++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +G
Sbjct: 345 ERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-DG 402

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
           + +P G  ++++ Y LH  P V+PNP  FDP  F P   + +H +AF+PFS G R+C+G+
Sbjct: 403 RSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSRNCIGK 460

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548
           ++AM +LKV  +  L  F ++ D       + A ++LK   G  +RL+
Sbjct: 461 QFAMNELKVATALTLLRFELLPDPTRIPIPI-ARLVLKSKNGIHLRLR 507



 Score = 87.0 bits (206), Expect = 1e-15
 Identities = 51/186 (27%), Positives = 95/186 (51%), Gaps = 6/186 (3%)

Query: 92  WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 150
           W+ G ++ V LYDP  ++VIL           YRF  PW+G GLL+  GQ W  HR+++ 
Sbjct: 89  WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147

Query: 151 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 207
           P FH ++LK ++ L   + R ++DK   L  + S  +   ++S  T++ +++ A     S
Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207

Query: 208 TQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVI 266
            Q D++   Y  A+  + +++  R    + + D ++  T   +   +   + H  T +VI
Sbjct: 208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI 267

Query: 267 KRKKEE 272
           + +K +
Sbjct: 268 QLRKAQ 273


>UniRef50_UPI00015B5E04 Cluster: PREDICTED: similar to CG8302-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG8302-PA - Nasonia vitripennis
          Length = 508

 Score =  178 bits (433), Expect = 4e-43
 Identities = 85/230 (36%), Positives = 144/230 (62%), Gaps = 5/230 (2%)

Query: 324 KRLAFLDLLLESSQSGVA-ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           K+ + L+ ++E+S+      SDE+I  +  T M  G D+    ++  L ++  H D QDK
Sbjct: 277 KKTSLLEYMMETSERNPEWFSDEDIINECCTFMLAGQDSVGTATAMTLFLLANHPDWQDK 336

Query: 383 VIEELDQIF--GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
             EELD+IF  G+++RP T QD   M++LE C+ E LRLYP VPI AR++ +++ +  + 
Sbjct: 337 CREELDEIFAEGETNRPPTMQDLRAMRWLECCIKEALRLYPSVPIFARKLGEDVKVGKH- 395

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             IP+G  ++I  Y  HR P  +P+P+ F P+ F PE S  RH YA++PFSAGPR+C+G 
Sbjct: 396 -VIPSGCGVIILPYSTHRLPHHFPDPHSFRPERFSPENSEKRHPYAYLPFSAGPRNCIGN 454

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           K+A+L++K ++S ILR +R+     +++ + +  + ++ + G  +++  R
Sbjct: 455 KFAILEMKAVISAILRRYRLGGVEGKTEVRPKFRLTVRASGGLWLKISQR 504



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 61/223 (27%), Positives = 108/223 (48%), Gaps = 8/223 (3%)

Query: 76  IVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLL 135
           ++  +A  D+  V + W+     V L +P D++ +L S  +  K   YR    +LG GL+
Sbjct: 68  VMSHTAYKDYGPVARFWVTLIPYVILLEPDDIQAVLGSAKHTSKIFVYRLLDNFLGKGLI 127

Query: 136 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-EASNFDCHDYMSECTV 194
            S    WR+HR+L+ P FHL+VL+ F+  F   +  + D+L + +    D   ++++   
Sbjct: 128 TSDVDTWRTHRRLLQPAFHLHVLQKFVGSFAERADRLADRLARYDNQQLDITKFVNDAVY 187

Query: 195 EILLETAMGVS-KSTQDQSGFEYA--MAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQ 251
           EIL ET +GV+  ST ++ G      +   K   ++  R  + WL  D ++K T   + +
Sbjct: 188 EILNETVLGVNVASTANEDGVVDLDDLPFRKGQVLMTHRLIRPWLIFDWIYKLTSTGQQE 247

Query: 252 TKLLDIIHGLTKKVIKRK----KEEFASGKKPSNLNETATTSE 290
            K    +     ++I+ K    ++  +  KK S L     TSE
Sbjct: 248 KKQSQDLSAACHRIIQEKRRLQRDSSSLTKKTSLLEYMMETSE 290


>UniRef50_Q9N525 Cluster: Cytochrome p450 family protein 29A3; n=6;
           Caenorhabditis|Rep: Cytochrome p450 family protein 29A3
           - Caenorhabditis elegans
          Length = 503

 Score =  177 bits (432), Expect = 5e-43
 Identities = 91/229 (39%), Positives = 139/229 (60%), Gaps = 4/229 (1%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           K+ + FLD+LL + +S V +S E+++++VDT MF GHDTT    S+    +  H DIQ  
Sbjct: 277 KRNMNFLDILLSNEESSV-LSPEDLRQEVDTFMFAGHDTTTTSVSWVCWNLAHHPDIQQN 335

Query: 383 VIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           V EE+  +FG D +  VT +   +++Y ER L E+ R+ P VP + RQ+  ++ +   G 
Sbjct: 336 VYEEIVSVFGEDPNEDVTTEGIKKLEYTERMLKESKRICPTVPAVLRQLISDMEI--GGV 393

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            IPAG  + IA   +H+  ++Y NP+ FDPD FLPE +A RH Y F+PFSAG R+C+G+K
Sbjct: 394 LIPAGANVAIAPMAIHKNANIYQNPDIFDPDRFLPEETAKRHAYDFIPFSAGLRNCIGQK 453

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +A L  KV++  +L+NF++         K   + + K + G  VRL  R
Sbjct: 454 FAQLNEKVMVIHLLKNFKIEPMGGYYSTKQVFEPVGKPSNGIPVRLVRR 502



 Score =  104 bits (250), Expect = 5e-21
 Identities = 62/211 (29%), Positives = 101/211 (47%), Gaps = 9/211 (4%)

Query: 71  DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 130
           D+F   V+K      +S+++  I     V+  D + V  IL S   +DK   Y FF  WL
Sbjct: 65  DLFSEAVEKG-----QSLIRHRILGTFYVWPLDGKTVSKILESTTELDKGGPYEFFNDWL 119

Query: 131 GNGLLIST-GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV---DKLKKEASNFDCH 186
           G G L+   G++WRSHRK++ PTFH   L+ + ++FN  SR VV   DK  K     D  
Sbjct: 120 GGGTLLEGYGERWRSHRKMLTPTFHFAKLEGYFEVFNTESRVVVDCLDKFAKSGETVDLF 179

Query: 187 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 246
            +   CT++ + +TAMG     Q Q+   Y  A+ +   +  L       +   ++    
Sbjct: 180 PFFKRCTLDTICKTAMGAKVDAQLQNSHPYITAIEQALQLGVLYAMNPHHQIPAIYWALG 239

Query: 247 YAKNQTKLLDIIHGLTKKVIKRKKEEFASGK 277
           + K + +  +I+   T+ VI  ++    SG+
Sbjct: 240 HQKKKDEYFNIMKTFTRNVIAERRTARESGE 270


>UniRef50_UPI00015B4DC8 Cluster: PREDICTED: similar to corpora
           allata cytochrome P450; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to corpora allata cytochrome P450 -
           Nasonia vitripennis
          Length = 513

 Score =  177 bits (431), Expect = 6e-43
 Identities = 84/223 (37%), Positives = 139/223 (62%), Gaps = 4/223 (1%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           LDLLL+  Q+G  ++D +++++V+T MF GHDT     S+ L  +G H + Q+++I E++
Sbjct: 293 LDLLLQMVQNGEKLTDNDLRDEVNTFMFAGHDTVGMSVSWILYSLGRHPEYQERIIREVE 352

Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448
            +   ++  + F+    + +L  C+ E  RLYP  P+IARQ+N  ITL ++   IP GTT
Sbjct: 353 DLLA-AEGELGFESYNRLHWLGACVKEAWRLYPVTPLIARQINSPITLQNHD--IPVGTT 409

Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508
           ++I +Y LHR P  +P P +F P+ FLP  S    + AF+PFSAG R+C+G K+A +++K
Sbjct: 410 VLINSYLLHRDPRYFPEPERFKPERFLPGASKPPSF-AFIPFSAGSRNCIGYKFATIEVK 468

Query: 509 VILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           V +  +LR +R  + L+E    L + ++L    G Q+ + PR+
Sbjct: 469 VTVLALLRAYRFRAILREDQLHLLSQVVLDNVGGIQLSITPRQ 511



 Score =  126 bits (303), Expect = 2e-27
 Identities = 70/230 (30%), Positives = 115/230 (50%), Gaps = 8/230 (3%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120
           N ++ +    D F  + + + ++    +  +W+G R  VF+Y    V  +LSS  +IDK+
Sbjct: 57  NFVQLLCNLEDFFAKLTEWAQEFG--DIYLLWVGLRPFVFVYRMEAVGTLLSSRQHIDKS 114

Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180
            EY + KPWLG+GL+ STG++W + RKL+ PTFH  +LK +  +    +   V+ L+ E 
Sbjct: 115 LEYEYLKPWLGSGLITSTGERWLARRKLLTPTFHSELLKGYFRVTLREADTFVECLRSEI 174

Query: 181 S--NFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRP 238
               FD   +     ++ +   AMG   + Q     EY  AV ++  I   R T I L+P
Sbjct: 175 GKLEFDIVPFAKRAALDTICVCAMGHQLNAQVNRRNEYVQAVQRLTAISQRRFTSILLKP 234

Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGK----KPSNLNE 284
           +LLFK +   +   + L +I      VI   K ++   +    + SN NE
Sbjct: 235 ELLFKVSTLGREHDRALRVIEDFVNGVITDTKRDWLGSRLRRARASNNNE 284


>UniRef50_UPI0000D56470 Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=5; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 495

 Score =  177 bits (431), Expect = 6e-43
 Identities = 87/227 (38%), Positives = 142/227 (62%), Gaps = 4/227 (1%)

Query: 324 KRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383
           K+  FL+ LL +S++   I +  I E++ TI+  G +TTA        ++GI+ +IQ+KV
Sbjct: 267 KKKRFLNHLLTTSETNPQIDELAILEEIQTILVTGSETTAITIGMVFIILGIYPEIQEKV 326

Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443
             EL+ I G  DR +T +D   ++YLER + ETLR+ P VP+I R V Q++ L +  K I
Sbjct: 327 RSELELILGPDDREITLEDINNLEYLERVIKETLRVLPIVPLITRTVEQDVKLGT--KTI 384

Query: 444 PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYA 503
           P+G+ +++    + ++ + +  P KFDPD FLPE +ANR   +F+PFS GPR+C+G KY 
Sbjct: 385 PSGSFVLVPIASIGKKAEFWAEPKKFDPDRFLPENNANRPRCSFIPFSYGPRNCIGFKYG 444

Query: 504 MLKLKVILSTILR--NFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548
           M+ LKV+L+T++R   F+     +  D +L   ++ K   GF+V+++
Sbjct: 445 MMSLKVLLATVIRKFTFKPSQYRRIEDVRLIYGMVAKPKHGFKVKIE 491



 Score =  128 bits (309), Expect = 4e-28
 Identities = 87/281 (30%), Positives = 133/281 (47%), Gaps = 9/281 (3%)

Query: 26  VPAVILWYAY-WRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYD 84
           + A+ L++   +   RR LY    K++         +A  F+GG    ++ +V+      
Sbjct: 15  ISALALFFLVKYNWKRRWLYYHGSKIDGPFGWPIIGSAHYFIGGQKVFYQKMVKVFET-- 72

Query: 85  HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144
             SV K W+G  LLV    P DVE++L+++    K + Y F      NGLLI+    WR 
Sbjct: 73  QPSVFKFWLGKDLLVVTSKPEDVEIVLNNNSCFGKPKFYDFAFKLFRNGLLIAPASIWRD 132

Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGV 204
            R++I PTF+  +L SFI++F  +   +V  L++  S  D    +  CT +I  ET   V
Sbjct: 133 RRRVINPTFNPKILNSFIEIFGKHGNKLVKVLEESCSESDIFLKLFRCTFDIACETLADV 192

Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264
             S   +   +Y   V++M DIL +R   IWL PD L+K + Y K   K    +    K+
Sbjct: 193 D-SELIKGQDKYLQTVIRMEDILAIRSFSIWLHPDFLWKRSFYGKEMEKASAEVFAFVKQ 251

Query: 265 VIKRKKEEFASG---KKPSNLNETATTSE--PSTGKLTSVE 300
           ++  KK         KK   LN   TTSE  P   +L  +E
Sbjct: 252 ILALKKASVTDDENYKKKRFLNHLLTTSETNPQIDELAILE 292


>UniRef50_UPI0000F2BA18 Cluster: PREDICTED: similar to Cytochrome
           P450 4A2 precursor (CYPIVA2) (Lauric acid
           omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450
           K-2); n=1; Monodelphis domestica|Rep: PREDICTED: similar
           to Cytochrome P450 4A2 precursor (CYPIVA2) (Lauric acid
           omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450
           K-2) - Monodelphis domestica
          Length = 519

 Score =  177 bits (430), Expect = 8e-43
 Identities = 86/229 (37%), Positives = 140/229 (61%), Gaps = 4/229 (1%)

Query: 322 QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           +KK L FLD+L ++  + G   ++EE++ +V+T  F G DT A G S+ L  + ++ + Q
Sbjct: 292 KKKYLNFLDILFQAKDEDGGGFTNEELENEVNTFRFAGQDTVAVGFSWTLYCLAMNPEYQ 351

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
            K  EE+  I  D +  +T+    +M Y   C+ E+ R+Y P+P +AR +NQ IT P +G
Sbjct: 352 KKCREEIQGILKDGES-ITWDHLTQMTYSTMCIKESFRMYSPIPKVARTLNQPITFP-DG 409

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
           + +P+ TT+ I  + LH  P ++ NP  FDP+ F PE +  RH YAF+PFSAG R+C+G+
Sbjct: 410 QTLPSDTTVTINIWALHYNPAIWENPKVFDPERFTPENTKKRHPYAFLPFSAGLRNCIGQ 469

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549
           ++AM  +KV L+  L  F ++ DL++    + + I+L+   GF   L+P
Sbjct: 470 QFAMNLIKVSLALTLLRFELLPDLEKPPIPI-SQIVLRSTSGFHFYLKP 517



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 37/126 (29%), Positives = 66/126 (52%), Gaps = 4/126 (3%)

Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVD---KLKKEASNFDCHD 187
           G GLL   G+KW  HR+L+ P FH N+LK +I +       ++D   KL+ + S+ D  D
Sbjct: 136 GKGLLSLEGEKWHYHRRLLTPAFHFNILKDYIYIMRNTVSLMLDKWEKLRTKDSSIDVFD 195

Query: 188 YMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFT-D 246
           ++S  +++  L+   G+    +++S F Y   + K+  ++  R        D ++K T D
Sbjct: 196 FISYMSLDTSLKATFGLQDFNKEESLFSYFQNMNKLLYLVRKRMETFLYYSDFIYKLTSD 255

Query: 247 YAKNQT 252
           + + QT
Sbjct: 256 HYEFQT 261


>UniRef50_UPI00015B5196 Cluster: PREDICTED: similar to cytochrome
           P450 CYP4C39; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP4C39 - Nasonia vitripennis
          Length = 507

 Score =  176 bits (428), Expect = 1e-42
 Identities = 87/234 (37%), Positives = 137/234 (58%), Gaps = 4/234 (1%)

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           +K +   L  LL  +     +++EE+++++ TI     DT A  SSF + M+GIH D+Q 
Sbjct: 276 EKSKTCILHRLLTVNSVTNELTEEELRDEIYTIYIASQDTLAVTSSFAVLMLGIHGDVQK 335

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           K   E+D++ G  D  V  +   ++KYLE  + ETLRL+P  P++ RQ+N E+ L ++  
Sbjct: 336 KARSEVDEVIGVGD--VNIESLSKLKYLEMVIKETLRLFPIAPLMVRQLNGELKLDNS-- 391

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            +P    +VIA Y  HR    + NP  F P+ F  + +  RH Y F+PFS GP  C+G+K
Sbjct: 392 ILPKDCQVVIAPYATHRSSKFWENPENFLPERFAIKETVKRHPYTFIPFSGGPMGCIGQK 451

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRMAK 555
           YA+  LK+IL+ IL+ + V SD+   D KL+ DI ++   G+++ LQ R  + K
Sbjct: 452 YALTALKMILANILQKYVVESDVTLRDIKLKTDISIRSMNGYKISLQARTNITK 505



 Score =  158 bits (383), Expect = 4e-37
 Identities = 84/268 (31%), Positives = 140/268 (52%), Gaps = 5/268 (1%)

Query: 38  MSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRL 97
           ++++R+ ELA KL          NAL+F      +   IV   A Y   + +++W+GP L
Sbjct: 33  VNKKRIIELAIKLPGPRAYPIIGNALKFACEPDQLLERIVDVIAPYADVTPMRLWMGPML 92

Query: 98  LVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNV 157
            V + +PRD+EV+L+S     K   Y+F  P++GNGL+  +G+ W++HRK+I+   +   
Sbjct: 93  YVIITEPRDIEVVLNSQQATSKGSAYKFLYPFIGNGLISGSGKSWKAHRKIISHILNQRT 152

Query: 158 LKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMSECTVEILLETAMG---VSKSTQDQS 212
           L SFI+ F+  S+  V KL+  A+   FD    +  CT++++ ET MG   ++       
Sbjct: 153 LDSFIETFDRRSKEFVKKLEPLANGEVFDIFHSLEGCTIDLVCETVMGYTDINALDNPNK 212

Query: 213 GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272
            F +  A  +M  I+H R  KIWL PD +F+ T    NQ +   +IH  T++ I+  +++
Sbjct: 213 EFVHYTADFRMYKIIHNRMMKIWLYPDWIFRITSNYSNQKRAQTMIHNFTERCIEAGRQD 272

Query: 273 FASGKKPSNLNETATTSEPSTGKLTSVE 300
               K  + +     T    T +LT  E
Sbjct: 273 MLKEKSKTCILHRLLTVNSVTNELTEEE 300


>UniRef50_Q4U3Y4 Cluster: CYP325C2; n=4; Anopheles gambiae|Rep:
           CYP325C2 - Anopheles gambiae (African malaria mosquito)
          Length = 264

 Score =  175 bits (426), Expect = 3e-42
 Identities = 88/229 (38%), Positives = 142/229 (62%), Gaps = 3/229 (1%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           KK L F D LL +  +G   +D E+   + +++  G+DTTA   +     + +H  IQ++
Sbjct: 37  KKPLIFADQLLAAQHNGNPFTDIEVTHNIYSMIAAGNDTTALQVTHTCLFLAMHPAIQER 96

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           V  E+  +F D D+ +  +D  ++ Y+ER + E+LRL P  P IARQ  ++I +   G  
Sbjct: 97  VYREVMDVFPDPDQDIEVEDLKKLTYMERVIKESLRLAPSGPNIARQTMKDIEIA--GVH 154

Query: 443 IPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
           IP  + +V++ + +HRR D++ P+ + FDPD FLPERS  R    F+PFSAG R+C+G +
Sbjct: 155 IPRDSLIVMSIFSMHRRKDIWGPDADLFDPDRFLPERSEGRSTNVFIPFSAGSRNCIGGR 214

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           YAML +KV+LS+ILR  R+ SDL+ +D + + D+ LK    + V+++ R
Sbjct: 215 YAMLSMKVMLSSILRRLRLRSDLQMNDLQFRFDLTLKLESEYFVQVEKR 263


>UniRef50_Q6PW73 Cluster: Cytochrome P450 CYP4AT1; n=1; Capitella
           capitata|Rep: Cytochrome P450 CYP4AT1 - Capitella
           capitata
          Length = 490

 Score =  175 bits (425), Expect = 3e-42
 Identities = 87/227 (38%), Positives = 143/227 (62%), Gaps = 4/227 (1%)

Query: 324 KRLAFLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           + L FLD+LL++  S G  ++DEEI+ +VDT MFEGHDTTA+G S+ L  +  H + QD+
Sbjct: 265 QNLDFLDILLDAKDSDGRGLTDEEIQHEVDTFMFEGHDTTASGLSWCLYNLARHPEYQDR 324

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
             +E+  + GD    V + D  ++ +L  C+ E+LRL+P VP I R + + +T P +G+ 
Sbjct: 325 CRKEVMDVMGDRS-DVEWDDMSKLTFLTMCIKESLRLHPAVPNIGRSLTKPMTFP-DGRT 382

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           +PA T L IA Y  H    ++ NP ++DP+ F  E S +R  ++F+PFSAGPR+C+G+ +
Sbjct: 383 VPAETDLGIAIYGCHHNSALWENPEQYDPERFNAENSKDRPPHSFIPFSAGPRNCIGQHF 442

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549
           AM +++ +L+  L+NF++  D      +L   ++LK   G  +++ P
Sbjct: 443 AMHEMRSVLAVCLKNFQLRID-DTRILELLPQLVLKAKGGLWLKVTP 488



 Score = 82.2 bits (194), Expect = 3e-14
 Identities = 49/168 (29%), Positives = 90/168 (53%), Gaps = 6/168 (3%)

Query: 93  IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPT 152
           IG  + + L  P  +  +LS+    D+   YR  KPW+G+GLL+S+G+KW  +R+L+ P 
Sbjct: 68  IGLYVCMELSHPSPLSKLLSTAEPKDRIS-YRTIKPWIGDGLLVSSGEKWARNRRLLTPA 126

Query: 153 FHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGVSKST 208
           FH +VLK ++ +F++ +  + DK +K  S  D       ++S  T++ LL+   G + S 
Sbjct: 127 FHFDVLKPYVGIFSSTANIMADKWRKILSKNDEPLEMFQHVSLMTLDSLLKCIFGQTGSV 186

Query: 209 QDQS-GFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLL 255
           Q++     Y  +V ++ +++  R        D ++ FT  A   + +L
Sbjct: 187 QNEGRDGSYIRSVYQLTELVMKRFQFFPYLIDWIYYFTPSALQVSPML 234


>UniRef50_Q8K4D6 Cluster: Cytochrome P450 4X1; n=15; Eutheria|Rep:
           Cytochrome P450 4X1 - Rattus norvegicus (Rat)
          Length = 507

 Score =  172 bits (418), Expect = 2e-41
 Identities = 87/223 (39%), Positives = 141/223 (63%), Gaps = 6/223 (2%)

Query: 328 FLDLLLESSQSG--VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIE 385
           FLD++L S+Q+G   A SD +++ +V+T M+ GHD +AA  S+ L  + ++ + QD+   
Sbjct: 284 FLDIVL-SAQAGDEKAFSDADLRSEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRT 342

Query: 386 ELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445
           E+  I GD    +T++   E+ Y   C+ ETLRL PP+P I+R++++ +TLP +G  +PA
Sbjct: 343 EIRSILGDGSS-ITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSKPLTLP-DGHSLPA 400

Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505
           G T+V++ + LH  P V+ +P  FDP  F  E S  RH  AF+PFS+GPR+C+G+++AML
Sbjct: 401 GMTVVLSIWGLHHNPAVWKDPKVFDPLRFTKENSEQRHPCAFLPFSSGPRNCIGQQFAML 460

Query: 506 KLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548
           +LKV ++  L  FRV +DL        +  +L+   G  + L+
Sbjct: 461 ELKVAIALTLLRFRVAADLTRPP-AFSSHTVLRPKHGIYLHLK 502



 Score = 90.6 bits (215), Expect = 9e-17
 Identities = 55/205 (26%), Positives = 105/205 (51%), Gaps = 14/205 (6%)

Query: 92  WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 148
           W+GP +   ++YDP   ++ LS     D   +Y  +   P+LG GLL   G +W  HR L
Sbjct: 83  WVGPFQAFFYIYDPDYAKIFLSR---TDPKTQYLHQLMTPFLGRGLLNLDGPRWFQHRCL 139

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMSECTVEILLETAMGV 204
           + P FH ++LK  +D+   +   ++DK +K    + +  +  ++++  T++I+++ A G 
Sbjct: 140 LTPAFHQDILKPCVDMMAHSVNMMLDKWEKTWTTQETTIEVFEHINLMTLDIIMKCAFGQ 199

Query: 205 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTK 263
             + Q    +E Y  A  ++ +I+  R    W   D++FK +       +L  +IH  T+
Sbjct: 200 ETNCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQCTE 259

Query: 264 KVIKRKKEEFASGKKPSNLNETATT 288
           K+I+ +K+     K   N ++T T+
Sbjct: 260 KIIQDRKKTL---KDQVNQDDTQTS 281


>UniRef50_Q17DZ0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 504

 Score =  171 bits (417), Expect = 3e-41
 Identities = 89/228 (39%), Positives = 131/228 (57%), Gaps = 3/228 (1%)

Query: 324 KRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383
           K  AFL+ LL     G + +D+EI     T++  G++TTA   +    M+ +H DIQ++V
Sbjct: 266 KSKAFLERLLTIQHKGRSFTDDEIINHAYTMLVAGYETTALQLTNVCMMLAMHPDIQERV 325

Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443
             E+  IF   D  +  +   ++ YL+  + ET+RLYP VP+IARQ N  + L      I
Sbjct: 326 ASEIKTIFPSLDMEILPEALKDLPYLDMTINETMRLYPVVPLIARQSNSSLELDK--VNI 383

Query: 444 PAGTTLVIATYKLHRRPDVYPNPN-KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           P GT  ++    LHRR DV+      F+PDNFLPE+   RH YAF+P SAGPR C+G +Y
Sbjct: 384 PTGTNFIVHIGALHRRKDVWGEEVLDFNPDNFLPEKVERRHPYAFIPLSAGPRVCIGNRY 443

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           AML LKV L  +L+ +R+ + L   D K +  + LK    + V+++ R
Sbjct: 444 AMLSLKVFLIRLLQRYRLSTKLTRKDLKFKFQVTLKLKIPYTVQMERR 491



 Score = 72.1 bits (169), Expect = 3e-11
 Identities = 43/126 (34%), Positives = 70/126 (55%), Gaps = 8/126 (6%)

Query: 75  NIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGL 134
           N   K  D +H  + KIW+GP  L+ +  P  V+ +L+    IDK   Y F +  LG GL
Sbjct: 53  NAYMKVFDKEHR-MSKIWLGPVPLINVQHPELVQKVLNE--CIDKPFAYDFME--LGQGL 107

Query: 135 LIST-GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSE 191
           +    GQ+WR HRK ++P F+  +L SFI +F   +  V+ +L+   +  +FD  +Y S 
Sbjct: 108 VSERYGQRWREHRKTLSPLFNTKILHSFIPIFERATSDVMKRLEVVCDGRDFDLLEYTSS 167

Query: 192 CTVEIL 197
           C+ +++
Sbjct: 168 CSAKMV 173


>UniRef50_Q27606 Cluster: Cytochrome P450 4e2; n=11; Diptera|Rep:
           Cytochrome P450 4e2 - Drosophila melanogaster (Fruit
           fly)
          Length = 526

 Score =  170 bits (413), Expect = 1e-40
 Identities = 84/206 (40%), Positives = 132/206 (64%), Gaps = 7/206 (3%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           +K++AFLD LL S+  G  ++ +E+ E+V T MFEGHDTT +G SF + ++  HQD Q K
Sbjct: 273 RKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRK 332

Query: 383 VIEELDQIFGDSD--RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           + +E  ++ G+S+  R  TFQ+  +MKYL+  + E  R+YP VP I R   ++  +  +G
Sbjct: 333 LFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVI--DG 390

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             +P GTTL +    L     V+ +P+KF P+ F  E+      + +VPFSAGPR+C+G+
Sbjct: 391 DLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPGP---FEYVPFSAGPRNCIGQ 447

Query: 501 KYAMLKLKVILSTILRNFRVISDLKE 526
           K+A+L++K ++S I+RNF V+  L E
Sbjct: 448 KFALLEIKTVVSKIIRNFEVLPALDE 473



 Score =  127 bits (307), Expect = 7e-28
 Identities = 77/271 (28%), Positives = 129/271 (47%), Gaps = 6/271 (2%)

Query: 20  LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79
           L+  L +P +++  AY  +S  R   + +K N         NA +     ++I   +   
Sbjct: 5   LYIFLALPLLLV--AYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSW 62

Query: 80  SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139
              Y  ++ V  WIG    V +   + +E ILSS   I K++ Y+   PWLG GLL STG
Sbjct: 63  WHQYGKDNFV-FWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTG 121

Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSEC---TVEI 196
            KW  HRK+I P FH N+L+ F ++ N NS   +  LK  A+  +  D+  +    T+++
Sbjct: 122 SKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDV 181

Query: 197 LLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLD 256
           + +TAMGVS +  +        A   MC  +++R      R +LL++        ++ L 
Sbjct: 182 ICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLK 241

Query: 257 IIHGLTKKVIKRKKEEFASGKKPSNLNETAT 287
            +   T ++I ++ E   SG   +N  +  T
Sbjct: 242 TLQDFTNEIIAKRIEAHKSGAVSTNAGDEFT 272


>UniRef50_Q16L55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 463

 Score =  169 bits (412), Expect = 1e-40
 Identities = 132/479 (27%), Positives = 229/479 (47%), Gaps = 43/479 (8%)

Query: 28  AVILWYA-YWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSAD-IFRNIVQKSADYDH 85
           +V+++ A Y+R SRR+       +N         +       S + IF   V+  + Y  
Sbjct: 11  SVLVFLAVYYRWSRRKTNAALANMNGPPKYPLIGHLYLLKYTSQEKIFETFVELGSTYS- 69

Query: 86  ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 145
            S + I +GP  LV +Y P  ++ +LSS   I +   Y FF+  +  G+  S    WR  
Sbjct: 70  -SPMGIELGPITLVVVYQPEHLQAVLSSPHCISRPFWYDFFR--VSRGIFSSPAHIWRGQ 126

Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNF--DCHDYMSECTVEILLETAMG 203
           RK++  +F   +L  F+ +FN  S  +   +         D    ++   ++ +  TA G
Sbjct: 127 RKVLNHSFGPGILNCFVSIFNEKSEILTKLMTSHVGRGERDFGHEIARAALDTIYSTAFG 186

Query: 204 VSKSTQDQ-SGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262
           ++   Q+   G +Y  A  +   ++  R          +F   +Y++        I+ LT
Sbjct: 187 LNFGMQEAPEGSKYLEAQEEFIGLVLKR----------IFSVINYSER-------IYRLT 229

Query: 263 KKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQ 322
           K   KR++E  +  +  +N    A  +E        +  ++   + G             
Sbjct: 230 KDY-KREQELLSYARTLTNRIMQARNAEQILSGAIGLPSVTTENTDG------------- 275

Query: 323 KKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           KK   FLD L E + ++   +S E+I E +DTI+F G+DTTA   S  L M+ +H D+Q+
Sbjct: 276 KKPQIFLDKLFELAVENKQQLSKEDIPEHLDTIIFAGNDTTATTMSNLLLMLAMHPDVQE 335

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           +V +E+ +   D ++PV+ +DT ++ Y E    ET+RL+P  P+I R    +I + S+  
Sbjct: 336 RVYQEVMEACPDLEQPVSMEDTAKLTYTEMVCKETMRLFPVGPLIGRIAEVDIKI-SDEH 394

Query: 442 KIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
            IPAG+ +    Y +HR   ++ P   +F+PD+FLPE  +  H YA++PFS G R+C+G
Sbjct: 395 VIPAGSEVGCGIYMVHRDRKIWGPRAEEFNPDHFLPENISKIHPYAYLPFSGGIRNCIG 453


>UniRef50_Q170T3 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 497

 Score =  169 bits (411), Expect = 2e-40
 Identities = 82/203 (40%), Positives = 130/203 (64%), Gaps = 4/203 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G KK+ AFLD+LL +S +G  +++ EI+E+VDT MFEGHDTT +   F L  +  H +IQ
Sbjct: 295 GAKKKDAFLDMLLRTSINGKPLTNLEIREEVDTFMFEGHDTTTSAVVFTLFNLAKHPEIQ 354

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
            KV +E+  + G D    +      ++ Y E  + ETLRL+P VP+I R+  +EIT+   
Sbjct: 355 QKVYDEIVSVIGKDPKEKIELSHLHDLSYTEMAIKETLRLFPSVPLIGRRCVEEITI--E 412

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCV 498
           GK IPAG  +++  Y + R    + NP++F P+ F  E S  + + Y ++PFSAGPR+C+
Sbjct: 413 GKTIPAGANIIVGIYFMGRDTKYFENPSQFIPERFEGEFSVEKFNPYKYIPFSAGPRNCI 472

Query: 499 GRKYAMLKLKVILSTILRNFRVI 521
           G+K+A+ ++K ++S +LR++  I
Sbjct: 473 GQKFALNEMKSVISKLLRHYEFI 495



 Score = 88.2 bits (209), Expect = 5e-16
 Identities = 62/210 (29%), Positives = 102/210 (48%), Gaps = 14/210 (6%)

Query: 102 YDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSF 161
           Y     + IL++    DK+ EY +   WLG+GLL+S   KW + RK I P FH  +L+ F
Sbjct: 114 YSIHTFQTILTNKHLTDKSGEYDYLSNWLGDGLLLSKRHKWHARRKAITPAFHFKILEQF 173

Query: 162 IDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILL-ETAMGVSKSTQDQSGFEYA 217
           +D+F+ N+  +VD L+K A +   FD   Y+    ++++  E   G     + ++   + 
Sbjct: 174 VDVFDRNAAELVDVLEKHADDGKTFDMFPYVLLYALDVICGELGTGCKLKRKHENLDNFR 233

Query: 218 MAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKK------E 271
                +  +   R   I  R  L +    Y K + K L ++HG T  VI  ++      +
Sbjct: 234 KCNGNITHVSIKRMFDIIRRTSLFYLTPSYQKLR-KALKVLHGYTDNVIVSRRNQLMISD 292

Query: 272 EFASGKKPSNLNETATTSEPSTGK-LTSVE 300
           EF + KK + L+    TS    GK LT++E
Sbjct: 293 EFGAKKKDAFLDMLLRTS--INGKPLTNLE 320


>UniRef50_Q6NT55 Cluster: Cytochrome P450 4F22; n=127;
           Deuterostomia|Rep: Cytochrome P450 4F22 - Homo sapiens
           (Human)
          Length = 531

 Score =  168 bits (408), Expect = 4e-40
 Identities = 81/230 (35%), Positives = 140/230 (60%), Gaps = 4/230 (1%)

Query: 322 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           Q K L F+D LLL   + G  +SDE+I+ + DT MFEGHDTT++G S+ L  +  + + Q
Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358

Query: 381 DKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           +K  EE+ ++  G     + + D  ++ +   C+ E+LR YPPV +++RQ  ++I LP +
Sbjct: 359 EKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP-D 417

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G+ IP G   +++ Y  H  P V+P+   ++P  F P+    R   A+VPFSAGPR+C+G
Sbjct: 418 GRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQP 549
           + +AM +L+V+++  L  FR+  D +    + + ++IL+   G  ++++P
Sbjct: 478 QSFAMAELRVVVALTLLRFRLSVD-RTRKVRRKPELILRTENGLWLKVEP 526



 Score = 92.3 bits (219), Expect = 3e-17
 Identities = 53/200 (26%), Positives = 107/200 (53%), Gaps = 9/200 (4%)

Query: 78  QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 134
           +K  D  H  V+ +W+GP L L+ L  P  ++ +L +   I   ++  Y F KPWLG+GL
Sbjct: 86  KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144

Query: 135 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 190
           L+S G KW  HR+L+ P FH ++LK ++ +FN ++  +  K +      A + D  +++S
Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204

Query: 191 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 250
             T++ L +     + + Q++   +Y  A++++  +   R  ++    D ++  +   + 
Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRR 263

Query: 251 QTKLLDIIHGLTKKVIKRKK 270
             +  D++H  T +VI+ ++
Sbjct: 264 FRQACDMVHHFTTEVIQERR 283


>UniRef50_Q9V558 Cluster: Cytochrome P450 4p1; n=5; Sophophora|Rep:
           Cytochrome P450 4p1 - Drosophila melanogaster (Fruit
           fly)
          Length = 513

 Score =  167 bits (407), Expect = 5e-40
 Identities = 85/228 (37%), Positives = 133/228 (58%), Gaps = 2/228 (0%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           KKR A LD L+ + + G+ I    I E+VDT+MFEG+DTT+ G  F L  M ++ D Q+ 
Sbjct: 287 KKRFAMLDTLIYAEKDGL-IDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQEL 345

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
             +E+ +   D    +      ++KYLE  + ET RL+P VPI+ R+  QE  L +NG  
Sbjct: 346 CYQEIQEHIDDDLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETEL-ANGLI 404

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           +P G  + I  + +HR    + +P +F P+ FLPE   +RH YA+VPFSAG R+C+G+KY
Sbjct: 405 LPKGAQITIHVFDIHRNAKYWDSPEEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKY 464

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           AM ++K ++  +L+ F+V+  +          I L+  +  +V+L  R
Sbjct: 465 AMQEMKTLMVVLLKQFKVLKAIDPQKIVFHTGITLRTQDKIRVKLVRR 512



 Score = 93.5 bits (222), Expect = 1e-17
 Identities = 61/215 (28%), Positives = 106/215 (49%), Gaps = 9/215 (4%)

Query: 61  NALEFVGGS-ADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDK 119
           N L+  G   A +F N  ++ A     S ++   G + +  + D    E +L+    I K
Sbjct: 57  NTLDLYGRDHAGVF-NYSRERAKEMGTSYIEYVFG-KAIYNIIDADSAENVLNHPNLITK 114

Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK-K 178
              Y F  P+L  GLL STG+KW + RK++ PTFH N+L  F ++F   S+  + + + +
Sbjct: 115 GLVYNFLHPFLRTGLLTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQFEGQ 174

Query: 179 EASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYA--MAVMKMCDILHLRHTKIWL 236
           +      HD +   T+  + ETAMGV      + G  Y    + ++ C I  L +  +W 
Sbjct: 175 DEVTITLHDVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLW- 233

Query: 237 RPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKE 271
             D LF+    AK+    LD++H  + ++I ++++
Sbjct: 234 -GDKLFEMF-AAKDFASALDVVHRFSSEIIAKRRD 266


>UniRef50_Q6TGT4 Cluster: Thromboxane A synthase 1; n=6; cellular
           organisms|Rep: Thromboxane A synthase 1 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 546

 Score =  167 bits (405), Expect = 9e-40
 Identities = 129/507 (25%), Positives = 232/507 (45%), Gaps = 28/507 (5%)

Query: 63  LEFVGGSADIFRNIVQKS-ADYDHE--SVVKIWIGPRLLVFLYDPRDVEVILSSHV--YI 117
           L F+G    +FRN   KS AD  ++   +   +IG R  V + DP  +  ++      + 
Sbjct: 54  LPFIGNLM-MFRNGFFKSQADLINKYGRICGYYIGRRSTVIIADPDMLRQVMVKEFNKFP 112

Query: 118 DKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK 177
           ++       KP + + L++  G++W+  R ++ PTF    +K  + L N  +  ++  LK
Sbjct: 113 NRMTARGITKP-MSDSLIMLKGEQWKRVRSILTPTFSAAKMKEMVPLINTATETLLRNLK 171

Query: 178 KEA---SNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKI 234
             A   ++F+ H      T++++   A G    +Q+     +     K       R   I
Sbjct: 172 SHAESENSFNIHKCFGCFTMDVIASVAFGTQVDSQNNPDDPFVHQASKFFAFSFFRPIMI 231

Query: 235 WLR--PDLLFKFTDYAKNQTK--LLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSE 290
           +    P LL        N+++  +        +K+IK++ +     ++   L        
Sbjct: 232 FFMAFPFLLRPLAGLLPNKSRDEMNSFFTQCIQKMIKQRDDLSPEQRRKDFLQLMLDVR- 290

Query: 291 PSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQ 350
            +  K  SVE       +  +           +          + SQ    ++++EI  Q
Sbjct: 291 -TNNKFLSVEHFDVVNDADEEAYDGHENSPANEST--------KRSQQKRMMTEDEIVGQ 341

Query: 351 VDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLE 410
               +  G++T++   +F   ++ +H + Q K+ EE+D+ F   +  V + +  E+KYL+
Sbjct: 342 SFIFLVAGYETSSNTLAFTCYLLAVHPECQKKLQEEVDEFFSRHEM-VDYANVQELKYLD 400

Query: 411 RCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFD 470
             + E+LRLYPP   +AR V ++  L  NG+ +P G +L I T  LH  P+ +  P KF 
Sbjct: 401 MVICESLRLYPPAFRVARDVEEDTVL--NGQFLPKGASLEIPTGFLHYDPEHWTEPTKFI 458

Query: 471 PDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS-DLKESDF 529
           P+ F PE  A RH + ++PF AGPRSCVG + A L++KV L  I R F V++ +  E   
Sbjct: 459 PERFTPEAKARRHPFVYLPFGAGPRSCVGMRLAQLEIKVALVHIFRRFNVLACEDTEIPL 518

Query: 530 KLQADIILKRAEGFQVRLQPRKRMAKA 556
           +L++   L    G  V++  R+ +  A
Sbjct: 519 ELKSHTTLGPKNGVMVKITERENLEDA 545


>UniRef50_Q16P39 Cluster: Cytochrome P450; n=7; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 504

 Score =  166 bits (404), Expect = 1e-39
 Identities = 74/224 (33%), Positives = 139/224 (62%), Gaps = 2/224 (0%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           F++ L++  ++    S + +   +D  +F G+DT+A      L M+ +H ++Q++  +EL
Sbjct: 282 FIECLVKYLRAEGETSKDAVYPHIDMTVFAGNDTSAKTICSILLMLAMHPEVQERCYQEL 341

Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447
            ++  + D+ ++++D   + YLE    ET+RL P VP +AR  + +I L ++   IPA  
Sbjct: 342 MEVCPEKDQHISYKDAANLTYLEMVCKETMRLLPAVPFMARITSGDIVL-NDQHTIPANC 400

Query: 448 TLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
           T+++  +++HR P ++ PN + FDPDNFLP+  A RH Y+++PFSAGPR+C+G +YA L 
Sbjct: 401 TIIMGIFQIHRDPRIWGPNADNFDPDNFLPDNVAKRHPYSYIPFSAGPRNCIGTRYAYLS 460

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
            K+++ +ILR +R+ + L     ++   ++L  + G Q+ ++ R
Sbjct: 461 SKIMVGSILRKYRLKTSLTMDKLRISCGLLLHISNGCQMAIEHR 504



 Score = 77.8 bits (183), Expect = 7e-13
 Identities = 48/190 (25%), Positives = 99/190 (52%), Gaps = 6/190 (3%)

Query: 87  SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHR 146
           S V I +GP   V ++DP  ++V+L S   +DK+ +Y F +  +   L+ + G  W+  R
Sbjct: 71  SPVCIHMGPLPHVAIFDPEQLQVVLHSQNCLDKSVQYSFLR--VSETLISAPGHLWKGQR 128

Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDY--MSECTVEILLETAMGV 204
           K + P+F   +L +F ++FN     +  +L++ A   + + Y  +S+CT++ +  TA G 
Sbjct: 129 KALNPSFGPAILTTFAEIFNNKCAILTKRLEEYAGKPERNFYRDISKCTLDQIYATAFGC 188

Query: 205 SKSTQDQSGFEYAMAVMK-MCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIH-GLT 262
             + Q     E ++ + +    ++  R   +W  P+ ++++T   K + +L  I H  +T
Sbjct: 189 DFNMQTSLDGERSLDLQEAYMKVMANRFFSVWKYPEFIYRWTAGYKKELELRRIYHETIT 248

Query: 263 KKVIKRKKEE 272
            K++++   E
Sbjct: 249 CKLVQQVSVE 258


>UniRef50_Q8N118 Cluster: Cytochrome P450 4X1; n=12; Mammalia|Rep:
           Cytochrome P450 4X1 - Homo sapiens (Human)
          Length = 509

 Score =  166 bits (403), Expect = 2e-39
 Identities = 87/228 (38%), Positives = 135/228 (59%), Gaps = 4/228 (1%)

Query: 322 QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           ++K   FLD++L +  +SG + SD ++  +V T +  GHDT AA  S+ L  + ++ + Q
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           ++  EE+  I GD    +T+    EM Y   C+ ET RL P VP I+R +++ +T P +G
Sbjct: 340 ERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP-DG 397

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             +PAG T+V++ + LH  P V+ NP  FDP  F  E S  RH YA++PFSAG R+C+G+
Sbjct: 398 CTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQ 457

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548
           ++AM++LKV ++ IL +FRV  D            ILK   G  + L+
Sbjct: 458 EFAMIELKVTIALILLHFRVTPD-PTRPLTFPNHFILKPKNGMYLHLK 504



 Score = 95.5 bits (227), Expect = 3e-18
 Identities = 56/198 (28%), Positives = 102/198 (51%), Gaps = 11/198 (5%)

Query: 92  WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 148
           WIGP    F +YDP   + +LS     D   +Y  +F  P LG GL    G KW  HR+L
Sbjct: 83  WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 204
           + P FH N+LK++I++   + + ++DK +K  S  D     +++++  +++I+++ A   
Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199

Query: 205 SKSTQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTK 263
             + Q  S  + YA A+ ++  I+  R   +    D++FK +       KL  +++  T 
Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTD 259

Query: 264 KVIKRKKEEFASGKKPSN 281
            +I+ +K+   +G K  N
Sbjct: 260 TIIQERKKSLQAGVKQDN 277


>UniRef50_A1BPR7 Cluster: CYP4AY1; n=2; Ips paraconfusus|Rep:
           CYP4AY1 - Ips paraconfusus
          Length = 491

 Score =  165 bits (402), Expect = 2e-39
 Identities = 88/229 (38%), Positives = 139/229 (60%), Gaps = 7/229 (3%)

Query: 321 GQKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           G KK++AFLD LL+   + G  +SD  I+ +VDT+MF GHDTTA   +F L ++  H ++
Sbjct: 261 GGKKKMAFLDHLLQYRDEQGKPLSDAFIRHEVDTVMFAGHDTTAVALAFALYLLAKHPEV 320

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q K   E  +I    ++ +T +D   + YL+  + ETLRLYP VP  +R + +++     
Sbjct: 321 QAKARAEAREIVEGREK-LTIKDIQNLNYLDLVVKETLRLYPSVPFYSRALKEDMVY-QE 378

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           GK +P G  ++I  Y ++R P VY NP++F P  FL +       ++ + FSAGPR+C+G
Sbjct: 379 GKILPKGLVVLIVAYTVNRNPAVYQNPDQFIPTRFLDKEPVP---FSLLSFSAGPRNCIG 435

Query: 500 RKYAMLKLKVILSTILRNFR-VISDLKESDFKLQADIILKRAEGFQVRL 547
           +K+A+L+LKV LS +L  F  VI D   S+  ++A  +LK   G +++L
Sbjct: 436 QKFALLELKVALSKLLLRFEFVIPDSDASEPVVEAVTVLKPKNGIRIKL 484



 Score =  104 bits (249), Expect = 7e-21
 Identities = 55/173 (31%), Positives = 100/173 (57%), Gaps = 5/173 (2%)

Query: 111 LSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSR 170
           L+S++ I K + Y   K WLG GLLIS G++WR+ RK++ P FH  +L+ FI++F   ++
Sbjct: 86  LTSNIPIHKGDIYAVLKNWLGGGLLISGGEEWRNSRKILTPAFHFTILEQFIEVFEDATQ 145

Query: 171 AVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDIL 227
            + D L  E ++    D + Y++  T++++ +T+MGV  + Q QS  +Y  AV +M  I+
Sbjct: 146 VLGDVLSAEVTSKGVVDIYPYLTRYTLDVICQTSMGVKLNIQQQSHSDYINAVAEMGKII 205

Query: 228 HLRHTKIWLRPDLLFKFT-DYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKP 279
             R        D  + FT DY K + + + ++H ++  +I+++++     K P
Sbjct: 206 VERAFNPLKVYDFTYIFTSDYWK-EKQYVKLLHQVSNSIIEQRRQALEDQKFP 257


>UniRef50_Q170S9 Cluster: Cytochrome P450; n=2; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 497

 Score =  165 bits (400), Expect = 4e-39
 Identities = 82/229 (35%), Positives = 139/229 (60%), Gaps = 4/229 (1%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           KK++A LDLLL ++  G  +SD++I+E+VDT  F GHDTTA+  +F L  +  + D+Q K
Sbjct: 269 KKKMALLDLLLRATVDGKPLSDDDIREEVDTFTFAGHDTTASALTFLLFNIAKYSDVQQK 328

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           + EE+  + G S   ++     +++YL+  + E+LRLYP VP+IAR   +   L  +   
Sbjct: 329 LFEEISSVVG-STSELSLHTLNDLRYLDLVIKESLRLYPSVPMIARIATENTKL--DDMP 385

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGPRSCVGRK 501
           IP  T + +  +++HR PD + +P  F P+ F   R   +H  + ++PFSAG R+C+G+K
Sbjct: 386 IPKCTCVSVDIFQMHRDPDRFEDPESFIPERFDAIRDGGKHNAFTYIPFSAGNRNCIGQK 445

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +A  +LK+ +  +++ FR+     + +  L+A+I+LK AE   +R   R
Sbjct: 446 FAQYELKIAVVKLIQTFRLELPSPDIEPILKAEIVLKPAEKLPIRFITR 494



 Score =  114 bits (275), Expect = 5e-24
 Identities = 78/254 (30%), Positives = 124/254 (48%), Gaps = 6/254 (2%)

Query: 20  LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVG-GSADIFRNIVQ 78
           +  V+L+P VI     +    R+L +  + L          +A E V   S +IF+ + +
Sbjct: 1   MLIVVLLPLVITLCLVFAFVHRKLLQFPN-LAGPPEWPIAGSATEIVNLSSIEIFKLLRR 59

Query: 79  KSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST 138
            +  Y     +  W     LVF   P   E IL++  Y  K+E+Y     W+G GLLIS 
Sbjct: 60  YAQQYGTAYKLSFWY-QYTLVFA-KPDIAEKILNTQSYASKSEDYDKVAEWIGYGLLISK 117

Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-EASNFDCHDYMSECTVEIL 197
           G+KW   RK++ P FH  +L+SF+ +FN  S  +  KL     S  D    +   T+++L
Sbjct: 118 GEKWFKRRKVLTPGFHFKILESFVRVFNEKSDVLCRKLASYGGSEVDVFPTLKLYTLDVL 177

Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257
            ETA+G S + Q +  F Y  AV ++  IL+ R   ++   D LF+FT   +   KL+  
Sbjct: 178 CETALGYSCNAQTEDSF-YPAAVEELMSILYWRFFNLFASVDTLFRFTKQYRRFHKLIGD 236

Query: 258 IHGLTKKVIKRKKE 271
               T K+I+ K++
Sbjct: 237 TREFTLKIIEEKRK 250


>UniRef50_UPI00015B5723 Cluster: PREDICTED: similar to cytochrome
           P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 523

 Score =  164 bits (398), Expect = 6e-39
 Identities = 83/226 (36%), Positives = 134/226 (59%), Gaps = 4/226 (1%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           + RL  L+ L++ +     ++D E++++  TI     DTT   SSF L  + I+Q+IQDK
Sbjct: 300 RPRLMLLEQLIDHNAKTNLMNDTELRDETYTIFTAAQDTTGVISSFALLNLAINQEIQDK 359

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           V EE+  + G+    VT +   E+KY E  + ETLRLYP  P++ R+   +I L +    
Sbjct: 360 VREEIRNVVGNDS--VTVEHLPELKYTELVIKETLRLYPIAPLMVREATGDIDLETC--T 415

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           +P G ++V+  Y+ HR    + +P KF P+ FLPE S  RH YA++PFS G R CVG+K+
Sbjct: 416 LPKGCSIVMIPYETHRSTKYWTDPEKFIPERFLPENSVGRHPYAYIPFSGGLRGCVGQKF 475

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQ 548
           A++ LK +L  ++R  R+ S       +L+ADI ++  +G+ V ++
Sbjct: 476 AIMCLKTMLVHVIRKVRLTSTQNLETLRLKADISVRSRDGYMVSVE 521



 Score =  137 bits (332), Expect = 6e-31
 Identities = 78/262 (29%), Positives = 125/262 (47%), Gaps = 4/262 (1%)

Query: 13  STFSAINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADI 72
           +TF  +    +++   V      W   R R   LA KL          NA  F     + 
Sbjct: 28  TTFFLVTTITLMMSFWVFRTLKQWYRDRARTLYLASKLPGPPTLPLIGNAHLFACNPEET 87

Query: 73  FRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGN 132
              I Q     D     + W+GP+L + L +PRD EVIL  H    K + Y F +P++G 
Sbjct: 88  LDKIKQIVQSVDTPG--RFWLGPKLFIILAEPRDYEVILGCHKASYKDKMYEFIEPFVGK 145

Query: 133 GLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDYMS 190
           GL+  +G   R+HRK I P  +   L  ++  F+ +SR   + L+++A    FD   +M 
Sbjct: 146 GLVSGSGPVHRAHRKAIMPMLNSKALNEYLKHFDTHSRICSELLEEKAGTGVFDIQPFMV 205

Query: 191 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKN 250
            CT +++ +T +G+  S+Q +   E      KM +++H R  K+WL  D +F +TD  K 
Sbjct: 206 HCTFDMIFDTILGMPGSSQKEGHKELVYWTEKMYELVHTRMIKVWLHADWIFSWTDLGKK 265

Query: 251 QTKLLDIIHGLTKKVIKRKKEE 272
           Q +   +IH   +  + RKK+E
Sbjct: 266 QKEGQHVIHSFIETAVARKKKE 287


>UniRef50_Q17PE3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 513

 Score =  164 bits (398), Expect = 6e-39
 Identities = 91/221 (41%), Positives = 135/221 (61%), Gaps = 7/221 (3%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           +K   F+D LL  S S    +DEEI   V TIM  G+DT+  G +     + I+ +IQ K
Sbjct: 279 RKPQIFIDQLLSLSNSSRPFTDEEILHNVLTIMIAGNDTSGLGVAHACLFLAIYPNIQQK 338

Query: 383 VIEELDQIF---GDSDRPVTFQDTL-EMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438
           V +E+ + F   G +DR     D L +++Y E  L E LR  P  P +ARQ  +E+ L  
Sbjct: 339 VYDEVMKHFPPDGPNDRISLDADFLRQLEYTEMFLKEVLRHCPVAPTVARQNLKELEL-- 396

Query: 439 NGKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 497
           +G +IPAG TL  + + LHRR D++ P+  KFDP+NF PER   RH YAF+PFS+G R+C
Sbjct: 397 DGVRIPAGNTLSFSFFALHRRKDIWGPDAEKFDPENFAPERCEKRHPYAFMPFSSGSRNC 456

Query: 498 VGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILK 538
           +G +YAM+ +KV++  I+RNF + ++L+ S  + +  + LK
Sbjct: 457 IGGRYAMISMKVMIVYIVRNFSLKTNLRHSHLRYKFGMTLK 497



 Score = 79.4 bits (187), Expect = 2e-13
 Identities = 50/208 (24%), Positives = 101/208 (48%), Gaps = 5/208 (2%)

Query: 85  HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144
           H+ + K  +GP + + +  P  +  +LS    ++K   Y F +  L +G+  +  + W+ 
Sbjct: 69  HDRMFKHLLGPIMGIGISHPDLMHKVLSHPDCLEKPFFYNFVQ--LEHGIFSAEYKLWKG 126

Query: 145 HRKLIAPTFHLNVLKSFIDLF-NANSRAVVDKLK-KEASNFDCHDYMSECTVEILLETAM 202
            RK + PTF++ +L SFI +F + +SR V D  K       D   + S+CT+E++  T +
Sbjct: 127 QRKALNPTFNMKILNSFISIFEDCSSRMVADLFKCANGETVDMFQFTSKCTLEMVCATTL 186

Query: 203 GVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLT 262
           G S   + +   E+   +  + +++  R   + L  D +++ T Y + + K+   I   +
Sbjct: 187 G-SNVLEREGSDEFLRNMEGLFELVGKRMLSVELFLDSIYRLTSYYRKEMKIRKKIEEFS 245

Query: 263 KKVIKRKKEEFASGKKPSNLNETATTSE 290
             +I+ K+ E        +L+  +T  E
Sbjct: 246 GNIIREKRREHMFCLNQQHLHNASTPKE 273


>UniRef50_O46054 Cluster: Cytochrome P450 4ae1; n=1; Drosophila
           melanogaster|Rep: Cytochrome P450 4ae1 - Drosophila
           melanogaster (Fruit fly)
          Length = 496

 Score =  164 bits (398), Expect = 6e-39
 Identities = 78/225 (34%), Positives = 140/225 (62%), Gaps = 5/225 (2%)

Query: 327 AFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           A LD LL ++  G  ++D++I+++V+T +FEGHDTT +  SF L ++  H+ +Q K+ EE
Sbjct: 274 ALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKLFEE 333

Query: 387 LDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445
           L   +G D  R V   D   + YL   + E+LRLYPP+P +AR + +++ +      IP 
Sbjct: 334 LRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEG--YIPV 391

Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505
           GT +V+  ++L R   ++ +P  F P+  L E +     Y+++PFSAGPR+C+G+K+A+L
Sbjct: 392 GTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALL 451

Query: 506 KLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           ++K +++ ++R+++++     +D +    I+L+   G  V L+PR
Sbjct: 452 EMKTMVTKVIRHYQLLP--MGADVEPSIKIVLRSKSGVNVGLRPR 494



 Score = 87.4 bits (207), Expect = 9e-16
 Identities = 52/182 (28%), Positives = 97/182 (53%), Gaps = 16/182 (8%)

Query: 103 DPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFI 162
           +PR ++ +L     + K   Y   + WLG+GLL+S G++W + RK+I PTFH ++L+ F+
Sbjct: 86  EPRHIDALLQGQHQLKKGTMYFALRGWLGDGLLLSRGKEWHTMRKIITPTFHFSILEQFV 145

Query: 163 DLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMA 219
           ++F+  S  +V++L+  +      + +  +    ++I+ ETAMGV+   Q     E   A
Sbjct: 146 EVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGADS-EVVHA 204

Query: 220 VMKMCDILHLRHTKIWLRPDLLFKF-------TDYAKNQTKLLDIIHGLTKKVIKRKKEE 272
           V  + +IL  R    ++RP LLF         + + K Q  ++  +H  T  +I++++  
Sbjct: 205 VKDLTNILATR----FMRPHLLFPHLFRLCWPSGFRKQQAGVI-CLHEFTNGIIEQRRRL 259

Query: 273 FA 274
            A
Sbjct: 260 LA 261


>UniRef50_Q9VLZ7 Cluster: Probable cytochrome P450 4d21; n=5;
           Sophophora|Rep: Probable cytochrome P450 4d21 -
           Drosophila melanogaster (Fruit fly)
          Length = 511

 Score =  163 bits (397), Expect = 8e-39
 Identities = 80/235 (34%), Positives = 145/235 (61%), Gaps = 6/235 (2%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G K ++  LD+LL+++     +SD +I+E+VD  +F G DTT +G S  L  +  H  +Q
Sbjct: 280 GGKAKMTLLDILLQATIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHPKVQ 339

Query: 381 DKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           + + EEL  + G D D  VT    LE+KYL+  + ET+RL+PPVPI+ R + +++ +   
Sbjct: 340 ECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKI--G 397

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP-ERSANRHYYAFVPFSAGPRSCV 498
              IP  T++++  Y ++R P+ +P+P  F P+ ++  + ++N    A++PFS+GP++C+
Sbjct: 398 EITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTSNTPPLAYIPFSSGPKNCI 457

Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRM 553
           G+K+A L++K ++S ++R++ ++     +D K     IL  + G  V L+PR R+
Sbjct: 458 GQKFANLQMKALISKVIRHYELLP--LGADLKATYTFILSSSTGNNVGLKPRTRV 510



 Score =  120 bits (290), Expect = 8e-26
 Identities = 70/204 (34%), Positives = 113/204 (55%), Gaps = 9/204 (4%)

Query: 75  NIVQKSADYDHE--SVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGN 132
           N +Q+  DY ++     ++WI    L++  D +  E ILSS   + KA  YRF + +LG+
Sbjct: 55  NFIQRFGDYFNKYGKTFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGD 114

Query: 133 GLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHD---YM 189
           GLL+STG KW S RK++AP FH   L++F+++ + NS  +V+KLK  A    C D   ++
Sbjct: 115 GLLLSTGNKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFV 174

Query: 190 SECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD--- 246
           S   +++  ETAMGV  + Q++  F Y  A+  +  I   R   + +R + LF       
Sbjct: 175 SLEALDVTTETAMGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLV 234

Query: 247 YAKNQTKLLDIIHGLTKKVIKRKK 270
           Y + Q K + I+   T KVI+ ++
Sbjct: 235 YRRLQ-KDIAIMQDFTDKVIRERR 257


>UniRef50_Q4STK8 Cluster: Chromosome undetermined SCAF14158, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14158, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 612

 Score =  163 bits (395), Expect = 1e-38
 Identities = 117/413 (28%), Positives = 201/413 (48%), Gaps = 38/413 (9%)

Query: 134 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCH----DYM 189
           LL+S G+ W   R+L+ P FH ++LK+++  FN ++  + DK ++ A+    H    + +
Sbjct: 174 LLLSNGEVWLRKRRLLTPAFHFDILKNYVAKFNTSTNTMHDKWRRLAAEGPTHVEAFEDV 233

Query: 190 SECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAK 249
           +  T++ LL+ A       Q QS  EYA A++++ D++  R  +I    D ++  T   K
Sbjct: 234 TLMTLDSLLKCAFSYDSDCQ-QSSSEYASAIVQLSDLIIERRQRILHHWDWIYWRTRQGK 292

Query: 250 NQTKLLDIIHGLTKKVIKRKK-------EEFASGKKPSNLNETATTSEPSTGK-LTS--- 298
              + L I+H  T+ V++ ++       E  A GKK  +  +    S+   GK LT    
Sbjct: 293 RFQQALSIVHKFTRDVVQERRTLIGQKGEMAAQGKK--DFVDIILLSKDEDGKGLTDEEI 350

Query: 299 -VEGLSF---GQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTI 354
             E  +F   G+   +              R   L L L SS S +++S           
Sbjct: 351 QAEANTFMFAGEQWLMLKLVDVSSNLTSGTRSVNLVLRLGSSCSQMSLS---------AC 401

Query: 355 MFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE-LDQIFGDSDRPVTFQDTLEMKYLERCL 413
              GHDTTA+   + L  +  H   Q+K  +E +D + G     + ++D   + +   C+
Sbjct: 402 SPTGHDTTASAICWSLYNLARHDHYQEKCRKEVMDLMEGRDVHEINWEDLSSLPFTTMCI 461

Query: 414 METLRLYPPVPIIARQVNQEITLPSNGKK------IPAGTTLVIATYKLHRRPDVYPNPN 467
            E+LRL+ PV  + R+  Q++ LP    K       P G   +++ Y  H  P V+ NP+
Sbjct: 462 RESLRLHSPVQAVTRRYLQDVELPGGHTKNETIACYPEGAICLVSIYGTHHNPAVWTNPH 521

Query: 468 KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520
            FDP  F P        +AF+PFS+GPR+C+G+K+A+ +L+V+++  L  FR+
Sbjct: 522 DFDPLRFDPTNQKGLSSHAFIPFSSGPRNCIGQKFALAELRVVVALTLLRFRL 574


>UniRef50_Q177R7 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 496

 Score =  162 bits (393), Expect = 3e-38
 Identities = 77/207 (37%), Positives = 131/207 (63%), Gaps = 2/207 (0%)

Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404
           +EI + + TI+  G DT+A   +F    + ++Q+ Q KV EE+ ++F +S+  +T +   
Sbjct: 290 QEIIDNIITIVGAGTDTSATAIAFTFLQLAMYQEHQQKVYEEIVKVFPESEPHITTEALK 349

Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY- 463
           +++Y +  L E LRLYP  PI+ R+   +ITL   G ++P G  L I  Y +HRR DV+ 
Sbjct: 350 KLQYTKMVLNECLRLYPVAPILLRENTADITL-CGGVRVPKGNILTIDVYNIHRRKDVWG 408

Query: 464 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 523
           P+ ++F P+ F PERSA RH +AF+ FS G R+C+G +YAM+ +K+++  +L+NFR  + 
Sbjct: 409 PDADEFIPERFSPERSAGRHPFAFLTFSGGSRNCIGSRYAMISMKIMMVYLLKNFRFKTK 468

Query: 524 LKESDFKLQADIILKRAEGFQVRLQPR 550
           ++E D + + D +L+   G  V+++ R
Sbjct: 469 IREEDIRYKFDALLRIEGGHLVQIEKR 495



 Score = 77.4 bits (182), Expect = 9e-13
 Identities = 50/195 (25%), Positives = 97/195 (49%), Gaps = 7/195 (3%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120
           N L F G + DI +    + A    +++ ++++GPR+L+   DP   + I++    ++K 
Sbjct: 42  NGLLFFGKN-DIKKFHKLRKAFDRKDALFRLYLGPRMLLCTSDPTVAQAIMTDANCMEKP 100

Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK-- 178
             Y+FF   L  G+  +    W+  RK + P F+  +L+SF+ +F   S+ ++ +L    
Sbjct: 101 YVYKFFN--LNEGVFAAKTHIWKGQRKALNPAFNSKILESFVSIFCEVSKTMIQRLDTVG 158

Query: 179 EASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRP 238
           +    +  ++ S CT+E++  T +G +    DQ   E    + +   I   R  K +L  
Sbjct: 159 KGDTINIMEHASRCTLEMVCSTTLGFNVDIFDQID-EMGHKIEQFFYIAARRILKFYLHV 217

Query: 239 DLLFKFT-DYAKNQT 252
           D ++++T DY   QT
Sbjct: 218 DSIYRWTKDYKDEQT 232


>UniRef50_UPI0001555B83 Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily V, polypeptide 2, partial;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           cytochrome P450, family 4, subfamily V, polypeptide 2,
           partial - Ornithorhynchus anatinus
          Length = 412

 Score =  161 bits (392), Expect = 3e-38
 Identities = 76/206 (36%), Positives = 119/206 (57%), Gaps = 2/206 (0%)

Query: 69  SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP 128
           S D+F+ ++Q + ++ H  + K+WIGP  +V LY    VEVILSS   I K+  YRF +P
Sbjct: 121 SVDLFQQVIQYTEEFRHMPLWKLWIGPVPMVILYHAESVEVILSSSKQISKSYVYRFLEP 180

Query: 129 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCH 186
           WLG GLL STG KWRS RK++ PTFH ++L+ F+ + N +++ +V+K +K      FDC 
Sbjct: 181 WLGLGLLTSTGGKWRSRRKMLTPTFHFSILEEFVGVMNEHAQTLVEKFEKHVDRDAFDCF 240

Query: 187 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD 246
             ++ C ++I+ ETAMG +   Q     EY   + +M D++  R    WL  D  +    
Sbjct: 241 MDITLCALDIICETAMGRNIQVQTNGDSEYVRTIYRMSDLIQRRILMPWLWLDPCYLLFQ 300

Query: 247 YAKNQTKLLDIIHGLTKKVIKRKKEE 272
             +   + L ++H  T +VI  + +E
Sbjct: 301 EGREHRQKLRVLHEFTDRVIAERSKE 326



 Score = 72.5 bits (170), Expect = 3e-11
 Identities = 36/69 (52%), Positives = 49/69 (71%), Gaps = 1/69 (1%)

Query: 324 KRLAFLDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           +R AFLDLLLE++      +S  +++E+VDT MFEGHDTTAA  SF L ++G   D Q K
Sbjct: 344 RRRAFLDLLLETADDARNGLSLRDVREEVDTFMFEGHDTTAAAMSFVLYLLGSCPDAQRK 403

Query: 383 VIEELDQIF 391
           V +ELD++F
Sbjct: 404 VNDELDRVF 412


>UniRef50_Q16L50 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 428

 Score =  161 bits (391), Expect = 4e-38
 Identities = 83/231 (35%), Positives = 135/231 (58%), Gaps = 2/231 (0%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G KK   F++ LL+  Q    I  E+I + + T+ F G+DTTA   S  L M+ +H DIQ
Sbjct: 199 GAKKIPIFVEKLLDEIQKSGHIKREDIDDHIVTMCFAGNDTTATTMSNILLMLAMHPDIQ 258

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           ++V +E+     D ++ V+ +D  ++ Y E    ET+R +   P+I R   Q++ L ++ 
Sbjct: 259 ERVYQEIIAACPDRNQQVSIEDAGKLTYTEMVCKETMRHFSIAPVIGRTATQDVKL-NDD 317

Query: 441 KKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
             IPA +TL+   YKLH  P  + P+   F+PDNFLP+  A RH Y+F+PFS GPR+C+G
Sbjct: 318 ITIPANSTLICCFYKLHMDPKNWGPDVKNFNPDNFLPDLVAKRHPYSFLPFSGGPRNCLG 377

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
            +YA L +K++L  ILR +R+ + L      ++ +  +K  +G  + ++ R
Sbjct: 378 VRYAWLSMKIMLVHILRRYRLRTTLTMDTITVKFNSFMKIEDGCPITVEER 428



 Score = 87.4 bits (207), Expect = 9e-16
 Identities = 53/179 (29%), Positives = 92/179 (51%), Gaps = 11/179 (6%)

Query: 93  IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPT 152
           +GP + +F+Y P  ++V+L+S   ++K  +Y FF+  +  G+  +    W+  RKLI P+
Sbjct: 1   MGPMVYIFVYTPEQLQVVLNSPHCLEKPLQYSFFQ--VSRGIFSAPVDLWKILRKLITPS 58

Query: 153 FHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSE---CTVEILLETAMGVSKSTQ 209
           F   +L SF+ +FN  S  +V+++ K        DY SE   C ++ +  TA GV    Q
Sbjct: 59  FGPGLLSSFVPIFNEKSSVMVEQMAKNVGK-PQRDYYSEIVLCFMDTICNTAFGVDCDLQ 117

Query: 210 -DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTD----YAKNQTKLLDIIHGLTK 263
              +G EY     K  DI+  R+ K W   + +++FT+    + K   K L ++   T+
Sbjct: 118 RSPAGAEYVETQEKYIDIVTERYLKPWQYLNFIYRFTNAYQIFKKRHGKFLALLTQATR 176


>UniRef50_Q6SPQ6 Cluster: CYP4BB1; n=2; Protostomia|Rep: CYP4BB1 -
           Nereis virens (Sandworm)
          Length = 508

 Score =  161 bits (390), Expect = 6e-38
 Identities = 81/231 (35%), Positives = 140/231 (60%), Gaps = 6/231 (2%)

Query: 323 KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           +K L FLD+LL++  + G  +SD EI+ +VDT MFEGHDTTA+G S+ L  +  H + Q 
Sbjct: 281 RKYLDFLDILLQARDEDGTGLSDLEIRNEVDTFMFEGHDTTASGISWALYSLAKHPEFQK 340

Query: 382 KVIEELDQIFGD-SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           K  +E+D++  D  ++ + + D  ++ YL  CL E++RL+ PVP+I+RQ+   IT+  +G
Sbjct: 341 KAQQEIDELLADRKNKWIMWDDLNQLPYLTMCLKESMRLWCPVPVISRQLLNPITI--DG 398

Query: 441 KKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
             +P  T   I    LH  P V+  + +++ P+ FLPE       +AF+PFSAGPR+C+G
Sbjct: 399 VTLPPHTLFDINIIALHHNPTVWGEDHDEYKPERFLPENINKMDNFAFLPFSAGPRNCIG 458

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           + +A  ++K  ++ I++ F +  D     +  + +++ +   G ++ + PR
Sbjct: 459 QNFAFNEMKTTIARIIQRFDLSVDESHPVYP-RPEVVTRAIHGIKLFMNPR 508



 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 48/207 (23%), Positives = 90/207 (43%), Gaps = 11/207 (5%)

Query: 75  NIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLG 131
           N  QKS    +  + ++W GP +  + L  P  +++++ +    + D    Y   +PWLG
Sbjct: 64  NGYQKSMAAKYNRLWRMWFGPFVPFISLCHPDTIKILVKTEEPKFTDGNAGYLLAEPWLG 123

Query: 132 NGLLISTGQKWRSHRKLIAPTF---HLNVLKSFIDLFNANS--RAVVDKLKKEASNFDCH 186
           N LL+    K    ++    +F   H   L   +   N NS  ++   K +KE +     
Sbjct: 124 NRLLLKCWTKVEEKQETPDTSFSFWHPQELHFCLQCGNRNSDEKSGQQKDRKERA-LTFR 182

Query: 187 DYMSECTVEILLETAMGVSKSTQDQ-SGFEYAMAVMKMCDILHLRHTKIWLR-PDLLFKF 244
                CT+ I+L  A    +  Q+      YA+AV+ +  ++  R    ++R    L+  
Sbjct: 183 RIFRLCTLSIILRCAFSYDEKIQETGERHPYAVAVLDLSRLMVERAFNPFVRMSKFLYGL 242

Query: 245 TDYAKNQTKLLDIIHGLTKKVIKRKKE 271
           T   +   K  D +H + + VI +++E
Sbjct: 243 TANGRTFFKHCDYVHKVAETVISQRRE 269


>UniRef50_Q17PE0 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 462

 Score =  160 bits (388), Expect = 1e-37
 Identities = 86/233 (36%), Positives = 137/233 (58%), Gaps = 4/233 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           G  K   FLD +L ++++G    DEEI+  V T++  G+DT+    ++   ++G++  IQ
Sbjct: 229 GYHKPQIFLDQILSANRAGKPFDDEEIQHNVRTMIAAGNDTSGQLMAYACLLLGMYPHIQ 288

Query: 381 DKVIEELDQIFGDSDRP-VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           +KV  E+ ++   + +  ++ +    + Y E  + E LRL P  P IAR     I L   
Sbjct: 289 EKVYSEIIELIPLTRKESISVEQLKTLTYTEMFMFECLRLCPIAPNIARLNMTPIEL--E 346

Query: 440 GKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
           G  IPAG    I+ Y LHRR D++ P+  +FDP+ F PERS  RH YAF+PFS G R+C+
Sbjct: 347 GITIPAGHIFFISFYSLHRRKDIWGPDAEQFDPERFSPERSVGRHLYAFLPFSGGSRNCI 406

Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           G +YAM+ +K++L  +LR +R  +DLK SD K + D++L       V+++ R+
Sbjct: 407 GWRYAMMSMKLMLVYLLREYRFRTDLKLSDLKFKFDMMLVLVFEHWVKIEKRR 459



 Score = 71.7 bits (168), Expect = 5e-11
 Identities = 58/229 (25%), Positives = 115/229 (50%), Gaps = 13/229 (5%)

Query: 61  NALEFVGGSADIFRNIVQKSADY-DHES-VVKIWIGPRLLVFLYDPRDVEVILSSHVYID 118
           NAL+FVG + +    + +K AD  +H + + ++ +G   L    DP   + IL+    ++
Sbjct: 5   NALQFVGKNGE---ELFKKFADMLNHPAKLFQMRMGVLRLFCTNDPDVAQKILTQ--CLE 59

Query: 119 KAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK 178
           K   Y FFK  L  GL  +    W+  RK +  TF+L +L SFI +F   SR +V++L+ 
Sbjct: 60  KPFLYDFFK--LDYGLFSAHYGLWKQQRKALNSTFNLKILHSFIPIFEECSRKLVNRLQN 117

Query: 179 E---ASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIW 235
               +   +   ++S+CT+E++  T +G+ +  Q +SG  +   + ++ DI+  R   I 
Sbjct: 118 HVGCSKPINLAQFVSQCTLEMVCGTTLGM-EHLQQESGSRFLHHIERVMDIMGERILSIP 176

Query: 236 LRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNE 284
           ++   L+ FT     +   L +      ++I   + +  + ++ + ++E
Sbjct: 177 MQITALYFFTPMFWQEMHSLKMNRQYAAEIIDEGRRKMKANEQSNTIDE 225


>UniRef50_Q7QCC3 Cluster: ENSANGP00000012179; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000012179 - Anopheles gambiae
           str. PEST
          Length = 504

 Score =  156 bits (379), Expect = 1e-36
 Identities = 85/232 (36%), Positives = 133/232 (57%), Gaps = 8/232 (3%)

Query: 323 KKRLAFLDLLLE---SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           +K   F+D L++   +  S    SDEEI + + T++  G++T+A   +    ++ +H  I
Sbjct: 275 RKPQIFIDQLMKMPLTDPSARHFSDEEISDHIYTMIVAGNETSATQLAHTCLLLAMHPHI 334

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q K  EE+  +    D+ +T +   ++ YLE  L E +RL P  PI+ RQ   EI L  +
Sbjct: 335 QTKAYEEVAGLVFSPDQEITIELMKDLHYLECVLKEAMRLMPVAPIVGRQSRAEIVL--D 392

Query: 440 GKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
           G +IP G+  +   Y LHRR DV+ P  ++F+P  FL +    RH YA +PFS GPR C+
Sbjct: 393 GHRIPQGSVFLFHFYALHRRKDVWGPTADEFEPGRFLAD--GGRHPYAHLPFSGGPRGCI 450

Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           G +YAM+ LK +L+ +LRN+ +++DL+  D + Q  I L  A    VRL+ R
Sbjct: 451 GYRYAMMSLKTLLAQLLRNYELMTDLRYEDIRYQYQISLNLAFPHAVRLRRR 502



 Score = 86.6 bits (205), Expect = 2e-15
 Identities = 59/217 (27%), Positives = 117/217 (53%), Gaps = 11/217 (5%)

Query: 61  NALEFVGGS-ADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDK 119
           N  +F+G S  ++F  +V       H+ +  +  G +L + L  P  V+ +L+      K
Sbjct: 43  NVGDFLGKSPGEVF--LVLDRHFRQHDRLFTLRFGSQLAIGLTHPELVQKVLTHPDCQAK 100

Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKE 179
            + Y+  +  L NGLL +    W+ HRK +  TF+  +L+SF+ +FN  ++ +V +L + 
Sbjct: 101 PDLYKVVR--LPNGLLAAKYDVWKVHRKTLNSTFNARILESFVPIFNDCTQRLVGRLDRY 158

Query: 180 ASNFD-CH--DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMC-DILHLRHTKIW 235
           A + D C+  +Y+S CT+E++  T++G      ++ G E  +A +++    + +R   I+
Sbjct: 159 ARSGDRCNILEYISACTLEMISRTSLG--GKVLEREGAEQFIANLEVALKTIGVRIFNIF 216

Query: 236 LRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272
           L  D +++FT   + + + ++I    T K+I+ K+EE
Sbjct: 217 LHIDFIYQFTALYRKEMRAINICQQFTSKIIQAKREE 253


>UniRef50_UPI0000D56467 Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 470

 Score =  156 bits (378), Expect = 2e-36
 Identities = 79/226 (34%), Positives = 141/226 (62%), Gaps = 8/226 (3%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           FL+ LL+ S++   ++D++I E+  T++    +TTA   +  L  + I   +Q+K+ EEL
Sbjct: 243 FLNNLLKMSEN---MTDDDILEETQTMLVAASETTALTMATVLLTLAIFPQVQEKIYEEL 299

Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447
           D I  ++D  +T +   +M YLE  + ET+R+ P VP I R++ +++ L  N   +P G+
Sbjct: 300 DAILWNTDE-ITLEHINKMVYLEAVIKETMRILPTVPFINRRMTEDLHL--NDCVVPTGS 356

Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507
            ++I+   +H  P ++ NP+KFDP+ FL ER  NR   AF+PF  GPR+C+G K+AML +
Sbjct: 357 NIIISIKNIHDSPLLWENPDKFDPERFLTERDPNRSRCAFMPFGYGPRNCIGFKFAMLSM 416

Query: 508 KVILSTILRNFRVISDLKESDFKLQA--DIILKRAEGFQVRLQPRK 551
           KV+++++L+NF     + +S  +++   +I+ K  +G++V+   RK
Sbjct: 417 KVMMASLLKNFTFEPAVYKSIAEIECFYNIVAKPKKGYKVKFSERK 462



 Score = 99.5 bits (237), Expect = 2e-19
 Identities = 63/210 (30%), Positives = 105/210 (50%), Gaps = 7/210 (3%)

Query: 65  FVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR 124
           F GG  D+++ +++ +       + KIW+G  L+     P D E+ILS      K +   
Sbjct: 18  FHGGYDDMYQAMLRLTKS--QPPLFKIWLGQDLIFVTSRPEDCEIILSK--CFTKGKFAT 73

Query: 125 FFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SN 182
           F  P    GLL +   KW+SHRK+I P+F++ +L SFI +FN +S+ +V+K++K A   +
Sbjct: 74  FMDPIFWEGLLTAPAIKWKSHRKIINPSFNIQILNSFIGVFNKHSKKLVEKMRKHAGSDS 133

Query: 183 FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLF 242
            D   ++   T++I  ET M +  +   +   EY    +K       R   +W  P+ ++
Sbjct: 134 VDVSYWLFRNTIDISCETLMDID-ADLIKGQEEYIDDCIKAEKYSSTRMIGVWYHPEFIW 192

Query: 243 KFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272
           K +   K      D I    +K+IK KK E
Sbjct: 193 KHSPLGKLTKATSDKILDFVRKIIKLKKLE 222


>UniRef50_Q16E69 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 348

 Score =  156 bits (378), Expect = 2e-36
 Identities = 75/179 (41%), Positives = 116/179 (64%), Gaps = 6/179 (3%)

Query: 324 KRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383
           +R A LD LL +S++   I +E I+E+VDT MFEGHDTTA+  +F   ++  HQ+ Q ++
Sbjct: 167 QRYALLDTLL-ASEAKNQIDEEGIREEVDTFMFEGHDTTASAFTFIFLVIANHQEAQRQL 225

Query: 384 IEELDQIFGDSDRP---VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           +EE++ +     +P   ++  D  E+K+++R + E LRLYPPVP I+R + ++  L    
Sbjct: 226 VEEIEAMIAGRIKPTEPLSMHDYSELKFMDRVIKECLRLYPPVPFISRAILEDALL--GD 283

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           + IP  +   +  + LHR PD +P+P +FDPD FLP     R+ YA+VPFSAGPR+C+G
Sbjct: 284 RFIPKDSMANLHIFDLHRDPDQFPDPERFDPDRFLPANVEKRNPYAYVPFSAGPRNCIG 342



 Score = 44.0 bits (99), Expect = 0.011
 Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 1/81 (1%)

Query: 198 LETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDI 257
           +ETAMGV   +   +  EY   + ++  +L LR    WL  +  ++   + +   K+L  
Sbjct: 72  IETAMGVKLDSMSMAD-EYRAKIQEVIKLLLLRVMNPWLVEEFPYRLLGFRRRLMKVLKP 130

Query: 258 IHGLTKKVIKRKKEEFASGKK 278
           IH  T+ +IK++++ F +  K
Sbjct: 131 IHAFTRSIIKQRRDLFHANVK 151


>UniRef50_UPI0000D56469 Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily v, polypeptide 2; n=1;
           Tribolium castaneum|Rep: PREDICTED: similar to
           cytochrome P450, family 4, subfamily v, polypeptide 2 -
           Tribolium castaneum
          Length = 392

 Score =  155 bits (377), Expect = 2e-36
 Identities = 78/207 (37%), Positives = 128/207 (61%), Gaps = 5/207 (2%)

Query: 347 IKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEM 406
           I+E++ TI+    ++TA      L+++GI+ +IQ KV +ELD IFG  DR  T +D  +M
Sbjct: 187 IEEELQTILITSSESTALTVGMILTVLGIYPEIQKKVSKELDSIFGHDDRETTLEDVQKM 246

Query: 407 KYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNP 466
           KYLE  + ET R+ P VP++AR  +++I L  +   IPAG+ +VI  +++ +  D + NP
Sbjct: 247 KYLECVIKETSRVLPAVPLLARLADKDIKL--DNYTIPAGSIIVIPIWQIGKNADFWKNP 304

Query: 467 NKFDPDNFLPER-SANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLK 525
            KFDPD FLPE    NR   +F+PFS GPR+C+G +Y+ + +KV+ +TILR + +     
Sbjct: 305 KKFDPDRFLPENCDPNRPRSSFIPFSYGPRNCIGFQYSNMLVKVLTATILRKYTIKCPQY 364

Query: 526 ES--DFKLQADIILKRAEGFQVRLQPR 550
            S    ++   I  +   GF+++++ +
Sbjct: 365 TSFEQVEIIFSITARPKHGFKIQMEKK 391



 Score = 73.3 bits (172), Expect = 2e-11
 Identities = 53/191 (27%), Positives = 87/191 (45%), Gaps = 10/191 (5%)

Query: 5   NAENVVPTSTFSAINLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALE 64
           N E +  TS  +   LF VL       W      +RR LY    K++          A  
Sbjct: 2   NFETINTTSALTWALLFIVLFFIIKYNW------NRRWLYYYGSKIDGPFAWPIIGIAHY 55

Query: 65  FVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR 124
           F+GG   +F N + K  +     + K W+G  L+V     +DVE+IL++    +K + Y 
Sbjct: 56  FIGGQK-VFYNQLTKLFEAQ-PPIFKFWLGQDLVVATSRLKDVEIILNN--CFEKPKFYN 111

Query: 125 FFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD 184
           F     GNGLL +    W+  RK+I   F L VL S++D+F+  ++ ++   +++    D
Sbjct: 112 FMCEVTGNGLLTARENIWKERRKMINQAFSLKVLHSYVDIFSKRAKCLISWFEEDFGKED 171

Query: 185 CHDYMSECTVE 195
               +  CT +
Sbjct: 172 VFFKLYRCTFD 182


>UniRef50_Q176V3 Cluster: Cytochrome P450; n=3; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 498

 Score =  155 bits (377), Expect = 2e-36
 Identities = 74/218 (33%), Positives = 134/218 (61%), Gaps = 4/218 (1%)

Query: 323 KKRLAFLDLLLESSQ-SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           K+ L  LD ++   +  G   SD E+ E + T++  G DT+A   ++    + ++ ++Q+
Sbjct: 269 KQHLNALDQIITMKRPDGTGFSDLEVNEHLYTLIGAGTDTSALNVAYTCLYLAMYPEVQE 328

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           KV+ E++Q+F   +  V  ++  +++Y E  + E LRL+P VP+ ARQ    I L  +G 
Sbjct: 329 KVLTEINQVFYSPEVEVNIENLKQLEYTEMVIKEILRLFPAVPLGARQTMSAIEL--DGI 386

Query: 442 KIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
           +IP    ++ + + LHRR D++ P+P +FDP+ F PE    RH +A++PFS G R+C+G 
Sbjct: 387 RIPKDQIIIFSMFTLHRRKDIWGPDPEQFDPERFRPEAIEARHPFAYLPFSGGLRNCIGH 446

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILK 538
           +YAM  +++IL  I++ F + +++K +D KL+ ++ LK
Sbjct: 447 RYAMNVMRIILLRIMQKFEIQTNMKPTDLKLKFEVTLK 484



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 50/195 (25%), Positives = 99/195 (50%), Gaps = 9/195 (4%)

Query: 86  ESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIS-TGQKWRS 144
           E + K+ +GP+ L+ +  P  ++ +L+ +   DK   Y F +  LGNGL+   +G++W  
Sbjct: 66  ERMGKLMLGPKPLITISHPDLMQQVLTRNDLYDKPFLYEFLR--LGNGLITERSGERWLQ 123

Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSECTVEILLETA 201
            RKL+ PTF+ ++L SF+   +A +  +V KL+  A   S  D + ++  CT+EI + T 
Sbjct: 124 TRKLLGPTFNTSMLTSFLSTMDARTMKMVSKLQSLADGHSEIDIYPFLLTCTLEIAISTT 183

Query: 202 MGVSKSTQDQSG-FEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHG 260
           MG  +   +  G  +Y   +      +  R   ++   + ++K +   K   +   I + 
Sbjct: 184 MG--RMDDEMPGQQDYIRNLEIFLKAVGERLVNVYYFIEPIYKLSKAYKIHDEARRICNE 241

Query: 261 LTKKVIKRKKEEFAS 275
            T +++ +++ E  S
Sbjct: 242 FTHRIVSKRRFEIQS 256


>UniRef50_Q178V0 Cluster: Cytochrome P450; n=2; Culicidae|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 502

 Score =  155 bits (375), Expect = 4e-36
 Identities = 78/225 (34%), Positives = 132/225 (58%), Gaps = 3/225 (1%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           F+D +L  + +   IS + + EQ+ TIM  G+DT+A   +     + I  ++Q+KV +E+
Sbjct: 280 FIDQVLSGNNTEADISTQNLSEQILTIMAAGYDTSANMVAHSCLFLAIFPELQEKVAQEI 339

Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447
             +  D ++ +T +   ++ YL++   E LRL P    IAR    +I L  +G +IP G 
Sbjct: 340 QTVLPDCEQELTAETLKDLPYLDKFFKECLRLTPVGSTIARVNMTDIEL--DGCRIPKGN 397

Query: 448 TLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
             +   Y LHRR D++ P   +FDP+NF PERS  RH +AF+PFS G R+C+G +YAM+ 
Sbjct: 398 IFIFNFYVLHRRKDIWGPYAEQFDPENFSPERSKGRHPFAFLPFSGGSRNCIGARYAMIS 457

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
            K+++  ++RNFR+ + ++  D K + ++ L  A    + L+ R+
Sbjct: 458 NKIMIIHLVRNFRMSTKIRFEDLKYRINVTLNLAFKHLITLEARR 502



 Score = 72.9 bits (171), Expect = 2e-11
 Identities = 44/148 (29%), Positives = 80/148 (54%), Gaps = 7/148 (4%)

Query: 61  NALEFVGGSADI-FRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDK 119
           +A  F+G S +  F N +      D   + K W+GP+L+ ++  P  V+ +L+     +K
Sbjct: 44  SATVFLGHSEERRFENFMNMLRQVDR--IGKGWLGPQLMFYVAHPELVQKVLTDPNCSEK 101

Query: 120 AEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK-- 177
              Y F +  L +GL  +    W+ +RK + PT ++ +L SF+ +F   SR++V+KLK  
Sbjct: 102 PFFYEFSR--LTHGLFSAKYSIWKPNRKALNPTMNVKMLNSFVPIFERFSRSMVEKLKCY 159

Query: 178 KEASNFDCHDYMSECTVEILLETAMGVS 205
            E +  D  D+ +EC +E++  T +G +
Sbjct: 160 PEGTPVDILDFTTECALEMVCGTTLGTA 187


>UniRef50_UPI0000D5558E Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=2; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 495

 Score =  151 bits (367), Expect = 4e-35
 Identities = 70/206 (33%), Positives = 120/206 (58%), Gaps = 3/206 (1%)

Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404
           ++  + + T M    DT ++  +F   M+G +  IQD V++EL ++ G     +   D  
Sbjct: 291 QDCTDHLMTFMATSQDTQSSAVAFTCMMLGAYPHIQDLVVQELREVMGKKTS-LDLTDVS 349

Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464
           ++KYLE CL E++RL+P  P I R   ++         IP G T++++ Y  HR P+ + 
Sbjct: 350 QLKYLEMCLKESMRLFPVGPFIFRDTTEDFQFDK--MVIPEGVTVILSIYHAHRSPEHWE 407

Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDL 524
            P++F P++F PE  + RH  AF+PFSAGPR C+ + Y+   +K++L+TI+ N+ +    
Sbjct: 408 KPDEFYPEHFAPEAMSKRHPCAFIPFSAGPRRCIAQHYSYTYMKILLATIVLNYEIECRF 467

Query: 525 KESDFKLQADIILKRAEGFQVRLQPR 550
           K  D KL ADI ++  +G+ ++L+ R
Sbjct: 468 KAEDVKLIADISIRPQQGYLIKLKDR 493



 Score =  126 bits (305), Expect = 1e-27
 Identities = 76/241 (31%), Positives = 124/241 (51%), Gaps = 13/241 (5%)

Query: 20  LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79
           + ++LLV  +I     +   RR+LY  A KL          N   F   + +IF N +  
Sbjct: 1   MLFLLLVILIICCLVKYHWDRRKLYLFAAKLQGPKAYPVVGNGPLFWCKNEEIFNNFMAA 60

Query: 80  SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139
           +A Y   S V++W+GP+L++F+ DP  +++IL S     K+  YRF +P+LG GL  S+G
Sbjct: 61  TAPYP--SPVRLWVGPKLVLFVKDPNQLQLILQSSKITTKSFLYRFLEPFLGKGLFTSSG 118

Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS--NFDCHDYMS----ECT 193
            + + HRKL+ P F   +++ +  LF  +S+  V+ L+K A+   F+   ++     E T
Sbjct: 119 PRQKHHRKLLQPLFSQRMIEGYCHLFQKHSKKFVEDLRKNANGPEFNISTFLQFTAFEAT 178

Query: 194 VEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTK 253
           +++LLE      + T      E    V K  +I+  R    WL  D+ FK + Y + QTK
Sbjct: 179 MDLLLE-----DQDTHSIDYNEIPNYVRKFYEIVFTRVKSFWLHLDIFFKLSSYYREQTK 233

Query: 254 L 254
           L
Sbjct: 234 L 234


>UniRef50_Q9VGB4 Cluster: Probable cytochrome P450 313a2; n=2;
           Drosophila melanogaster|Rep: Probable cytochrome P450
           313a2 - Drosophila melanogaster (Fruit fly)
          Length = 493

 Score =  150 bits (364), Expect = 8e-35
 Identities = 144/537 (26%), Positives = 245/537 (45%), Gaps = 60/537 (11%)

Query: 23  VLLVPAVILWYAY-WRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSA 81
           +L+  ++ILW  + W  SRR+LY L  +L          N++ ++     I R  +    
Sbjct: 6   LLIAASLILWIRFLW--SRRKLYMLMMQLPGRMGLPLLGNSVRYL----IISRGKMSSRT 59

Query: 82  DY--DHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEY-RFFKPWLGNGLLIST 138
            Y   H S    WIG   +V   DP+  E +L+S   I+++ +        +G GLL   
Sbjct: 60  TYMDKHGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQ 119

Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSEC---TVE 195
           G KW + RK + P F  +VL SF+ +FNA +  +V          +  D +S+    +  
Sbjct: 120 GSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGE-KDVLSDLIRWSFA 178

Query: 196 ILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLL 255
           I  +T +G   +  D   FE   A++K    +        LR  ++  F  + +N  K++
Sbjct: 179 IATQTTLGTDVTKDD--NFEND-AILKTYQSM--------LRLTIINIFVPFVQN--KIV 225

Query: 256 DIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXXXX 315
             + GL      R+++  A  K  +N+ +    S P           ++ +S  LK    
Sbjct: 226 SKLFGLE---WLRRRDASAINKMINNILDKKLNSNPE----------NYCESE-LKTVIH 271

Query: 316 XXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGI 375
                 +   ++ ++L  E S   +A              FE    T   +   L+M   
Sbjct: 272 RAIELFRNDEMSLMELGAECSSMVLA-------------AFETSAHTVYYALVLLAMFPE 318

Query: 376 HQDIQDKVIEELDQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEI 434
           HQ++   V  E+ + F       VT  D  ++ YL+R L ETLRL P VP  +R+  +++
Sbjct: 319 HQEM---VFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRETLEDL 375

Query: 435 TLPSNGKKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAG 493
            L SNG  IP G T+ I  +   R  D +     +F+P+NFLPE+  +RH YAF+PFS G
Sbjct: 376 RL-SNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFSKG 434

Query: 494 PRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
            R+C+G +Y ++  K+ L  ILRN+++ +     + +    +++K A+  Q+  + R
Sbjct: 435 KRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQLAFERR 491


>UniRef50_Q5XM61 Cluster: Cytochrome P450; n=9; Pancrustacea|Rep:
           Cytochrome P450 - Anopheles gambiae (African malaria
           mosquito)
          Length = 147

 Score =  149 bits (362), Expect = 1e-34
 Identities = 70/139 (50%), Positives = 99/139 (71%), Gaps = 5/139 (3%)

Query: 321 GQKKRLAFLDLLLESSQSGVA---ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 377
           G++KRLAFLDLLL+S+ +G     ++DE+++E+VDT MFEGHDTT AG S+ L ++ +H 
Sbjct: 11  GRRKRLAFLDLLLQSATTGTGSPLLTDEDVREEVDTFMFEGHDTTTAGMSWALFLLALHP 70

Query: 378 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 437
           ++Q++V +E+D IFG SDRP T QD   M+ LERCL ETLRLYP V    R  ++++TL 
Sbjct: 71  EVQERVHQEIDSIFGGSDRPATMQDLTAMRLLERCLKETLRLYPSVAFFGRTTSKDVTL- 129

Query: 438 SNGKKIPAGTTLVIATYKL 456
             G  +PAGT + I  Y +
Sbjct: 130 -GGYHVPAGTIVGIHAYNV 147


>UniRef50_Q6PH32 Cluster: Cytochrome P450, family 4; n=7;
           Clupeocephala|Rep: Cytochrome P450, family 4 - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 458

 Score =  149 bits (361), Expect = 2e-34
 Identities = 73/174 (41%), Positives = 113/174 (64%), Gaps = 3/174 (1%)

Query: 323 KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           ++ L FLD+LL +  +    +SDE+I+ +VDT MFEGHDTTA+G S+    +  + + Q+
Sbjct: 281 RRYLDFLDILLSARDEHQQGLSDEDIRAEVDTFMFEGHDTTASGISWIFYNLACNPEHQE 340

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           K  +E+ Q     D  + ++D  ++ Y   C+ E+LRL+PPVP I+R++ + +T   +G+
Sbjct: 341 KCRQEIQQALDGKDT-LEWEDLNKIPYTTMCIKESLRLHPPVPGISRKLTKPLTF-FDGR 398

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495
            +P G T+ ++ Y +H    V+ NP KFDP  FLPE +ANR  +AFVPFSAGPR
Sbjct: 399 TVPEGCTIGVSIYGIHMNSTVWENPYKFDPLRFLPENAANRSPHAFVPFSAGPR 452



 Score =  111 bits (268), Expect = 4e-23
 Identities = 59/186 (31%), Positives = 103/186 (55%), Gaps = 6/186 (3%)

Query: 91  IWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149
           +W GP L V  ++ P   + IL++    D    Y+FF PWLG+GLL+STGQKW  HR+L+
Sbjct: 83  LWFGPSLAVLNIHHPSYAKTILTTTEPKDDYA-YKFFIPWLGDGLLVSTGQKWFRHRRLL 141

Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVSK 206
            P FH +VLK ++ L + +++ ++DK +   +   +F+   ++S  T++ +++ A   + 
Sbjct: 142 TPGFHYDVLKPYVKLISDSTKVMLDKWEVHSRSEESFELFKHVSLMTLDSIMKCAFSCNS 201

Query: 207 STQDQSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKV 265
           + Q  SG   Y  AV  +C +++LR          +F  + +     K   I H  T +V
Sbjct: 202 NCQTDSGTNPYIQAVFDLCHLVNLRFRVFPYHSKAIFHLSPHGYRFRKAASIAHNHTAEV 261

Query: 266 IKRKKE 271
           I+++KE
Sbjct: 262 IRKRKE 267


>UniRef50_Q8WQN5 Cluster: Cytochrome P450 CYP4H14; n=22;
           Endopterygota|Rep: Cytochrome P450 CYP4H14 - Anopheles
           gambiae (African malaria mosquito)
          Length = 151

 Score =  149 bits (361), Expect = 2e-34
 Identities = 66/153 (43%), Positives = 102/153 (66%), Gaps = 4/153 (2%)

Query: 350 QVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRP--VTFQDTLEMK 407
           +VDT MFEGHDTT +G SF +  +  + D+Q++V EE+  I G   +   +T+Q+  E K
Sbjct: 1   EVDTFMFEGHDTTTSGISFTIYELARNPDVQERVYEEIVSILGKDHKTAELTYQNLQEFK 60

Query: 408 YLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPN 467
           YL+  + E LR+YPPV II R + +++ L  NG  +PAG  +++  Y +HR P++YPNPN
Sbjct: 61  YLDLVVKEGLRMYPPVGIIGRALVEDLEL--NGTTVPAGQNVLVPIYVIHRNPEIYPNPN 118

Query: 468 KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
           +FDP  F  +  + R  + ++PFSAGPR+C+G+
Sbjct: 119 QFDPSRFAEDAESKRGPFDYLPFSAGPRNCIGQ 151


>UniRef50_Q095M8 Cluster: Cytochrome P450 4A5; n=1; Stigmatella
           aurantiaca DW4/3-1|Rep: Cytochrome P450 4A5 -
           Stigmatella aurantiaca DW4/3-1
          Length = 374

 Score =  148 bits (358), Expect = 4e-34
 Identities = 76/228 (33%), Positives = 129/228 (56%), Gaps = 4/228 (1%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           +K L  + +     ++G  +SDE+++ ++  +   GHDTTA G +F   ++  H +   +
Sbjct: 151 RKDLLAMYMSAVDEETGEGMSDEQLRHELMNLFLAGHDTTANGLAFTFYLLSKHPEALKR 210

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           V EE D + G+  R VT +D  ++ Y      E LR+YPP   ++R   +E  L  N   
Sbjct: 211 VDEERDAVLGNG-RMVTNEDLPQLNYARWSFEEALRIYPPTFAMSRTSVRE--LKHNDYV 267

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           IPAG+ + +  + LHR P ++PNP+ F+P+ F PERS  RH +A++PF AGPR C+G   
Sbjct: 268 IPAGSNIFVCQWALHRNPRLWPNPDHFEPERFSPERSEGRHRFAYLPFGAGPRICIGAHL 327

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           A  + ++I++ +L+ FR+ S+    + +L A + +    G  +RL  R
Sbjct: 328 ARTEAQMIIAMLLQRFRLNSE-PGYEPRLVARLFVTAEPGISMRLSRR 374


>UniRef50_Q5V5P9 Cluster: Cytochrome P450; n=3;
           Halobacteriaceae|Rep: Cytochrome P450 - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 445

 Score =  148 bits (358), Expect = 4e-34
 Identities = 76/223 (34%), Positives = 131/223 (58%), Gaps = 6/223 (2%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           FL +LL +   G   S E++++++ T++  GHDTTA   ++   ++  H +++ +V EEL
Sbjct: 229 FLSVLLRARDDGNQ-SPEQLRDEMMTMLLAGHDTTALTLTYTWFLLSEHPEVEQRVHEEL 287

Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447
           D + GD DRP   +   E+ YLE  + E +RLYPPV  I R+  +++TL  +G ++ AGT
Sbjct: 288 DDVIGD-DRP-GMEHVRELDYLEWVIQEAMRLYPPVYTIFREPTEDVTL--SGYEVEAGT 343

Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507
           TL++  + +HR    Y +P  FDP+ + PER++ R  +A+ PF  GPR C+G+  AML+ 
Sbjct: 344 TLMVPQWGVHRSERFYDDPETFDPERWKPERASERPRFAYFPFGGGPRHCIGKHLAMLEA 403

Query: 508 KVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           ++I +T    +R +    E+  +L   +     +   +R+Q R
Sbjct: 404 QLITATTASQYR-LEFQGETPLELLPSLTAHPRQKMSMRVQER 445



 Score = 52.4 bits (120), Expect = 3e-05
 Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 3/124 (2%)

Query: 88  VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR--FFKPWLGNGLLISTGQKWRSH 145
           V +  +GP   V L DP  +E +L S     +  +++       LG+GLL+S G+ W   
Sbjct: 38  VARFDMGPMDTVMLCDPTAIERVLVSEADRFRKPDFQGDALGDLLGDGLLLSEGETWEQQ 97

Query: 146 RKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVS 205
           RKL  P F +  L    D    ++   +          D    M+  T++++L+  MGV 
Sbjct: 98  RKLANPAFSMARLSGMADRITGHAEDRIADW-SHGDVIDAEQSMTRVTLDVILDLMMGVE 156

Query: 206 KSTQ 209
            S Q
Sbjct: 157 LSEQ 160


>UniRef50_A6GGL1 Cluster: Cytochrome P450 family protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Cytochrome P450 family
           protein - Plesiocystis pacifica SIR-1
          Length = 454

 Score =  147 bits (356), Expect = 8e-34
 Identities = 73/224 (32%), Positives = 135/224 (60%), Gaps = 7/224 (3%)

Query: 329 LDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           LD+L+ +    +G  +   ++++++ T++  GH+TT+   S+   ++  H +   ++  E
Sbjct: 224 LDMLMAARDEDTGEGMDARQLRDELMTLVVAGHETTSNALSWTWYLLSQHPEHVQRLRAE 283

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           +D++ GD  R  T +D  ++++ ER L E++R+YPPV  + R+ ++ + +   G ++P G
Sbjct: 284 VDEVLGD--RLPTPEDLAKLEHTERVLKESMRVYPPVWAVEREPSEAVEV--GGYRLPKG 339

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
           T + I+ Y LHR P  +P+P +FDPD F PERSA R  YA++PF AGPR C+G  +A+ +
Sbjct: 340 TMIGISPYVLHRDPQHWPDPERFDPDRFTPERSAGRPRYAYLPFGAGPRVCIGAGFALTE 399

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
            K IL+ ++R F  +  +      ++  I L+   G ++RL+ R
Sbjct: 400 AKAILAMLVRRFD-LERVPGQAVHMEPGITLRPKHGLRMRLRVR 442



 Score = 57.6 bits (133), Expect = 8e-07
 Identities = 40/132 (30%), Positives = 64/132 (48%), Gaps = 5/132 (3%)

Query: 84  DHESVVKIWIGPRLLVFLYDPRDV-EVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKW 142
           DH   V+   GP   V L D  DV +V+++      K++ Y   K  LG GL+ S G  W
Sbjct: 30  DHGDHVRFRFGPFSYVSLRDLEDVRKVLVTDAQRYTKSKVYTALKLLLGEGLVTSEGAMW 89

Query: 143 RSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK--KEASNFDCHDYMSECTVEILLET 200
           +  RKL +P F    + SF +   A +R + ++ +   + +  D HD M   T+ I+  T
Sbjct: 90  QRQRKLSSPAFRPRAVASFTEAMGACTRDLGERWRGLGDGAELDVHDEMMRLTLRIVGMT 149

Query: 201 AMGVSKSTQDQS 212
              VSK  + ++
Sbjct: 150 L--VSKDLEGEA 159


>UniRef50_Q9VG40 Cluster: Probable cytochrome P450 313a4; n=3;
           Sophophora|Rep: Probable cytochrome P450 313a4 -
           Drosophila melanogaster (Fruit fly)
          Length = 478

 Score =  147 bits (356), Expect = 8e-34
 Identities = 74/225 (32%), Positives = 135/225 (60%), Gaps = 4/225 (1%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           FL+L+ +  + GV  + + ++++ + I+F   +TTA    + L ++ +  + Q++  EE+
Sbjct: 255 FLNLVTDLMRRGV-FTLKNVEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEI 313

Query: 388 DQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
             IF ++ D  V++ DT +M YL+  L E++R+ PPVP+++RQ +Q++ L SNG  +P G
Sbjct: 314 KTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPPVPVVSRQTSQDLKL-SNGIVVPKG 372

Query: 447 TTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505
             + I  Y +HR   ++ P+   F+PD+FLP    ++H YA++PF+ G R+C+G +YA++
Sbjct: 373 VQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDKHPYAYIPFTKGIRNCIGWRYALI 432

Query: 506 KLKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
             KV L+ +LRN+R  +     +     DI +K      + LQ R
Sbjct: 433 SAKVTLAKLLRNYRFKTSFPFENLYFVEDITMKLKSVPLLELQKR 477



 Score = 62.9 bits (146), Expect = 2e-08
 Identities = 53/197 (26%), Positives = 86/197 (43%), Gaps = 7/197 (3%)

Query: 20  LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79
           L + L    + L + Y+  SRRR Y L  K+           A  ++    DI  N    
Sbjct: 2   LTWTLWCGLLFLLWIYFLWSRRRFYLLTLKIPGPLGYPILGMA-HWLMRREDIL-NAFGC 59

Query: 80  SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139
             D  H   +  W+GP   + + DP+ V+ I +S   ++K   Y+      G GL     
Sbjct: 60  FLD-KHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGVGLFSLKD 118

Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK--KEASNFDCHDYMSECTVEIL 197
            +W  HRKL+ P F   VL SF+ +FN  +  ++D+L+  ++    D    +   T+ I 
Sbjct: 119 PRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLIPLLQSFTLGIA 178

Query: 198 LETAMGVSKSTQDQSGF 214
            +T MG     +D+  F
Sbjct: 179 TQTTMG--SDVKDEESF 193


>UniRef50_UPI00005A2E9B Cluster: PREDICTED: similar to cytochrome
           P450, family 4, subfamily A, polypeptide 11; n=1; Canis
           lupus familiaris|Rep: PREDICTED: similar to cytochrome
           P450, family 4, subfamily A, polypeptide 11 - Canis
           familiaris
          Length = 411

 Score =  146 bits (354), Expect = 1e-33
 Identities = 79/222 (35%), Positives = 128/222 (57%), Gaps = 27/222 (12%)

Query: 323 KKRLAFLDL-LLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           K+ L FLD+      ++G  +SD++++ +VDT  FEGHDTTA+G S+ L  +  H + Q 
Sbjct: 169 KRHLDFLDISFFAKMENGRGLSDKDLRAEVDTFKFEGHDTTASGISWILYALATHPEHQQ 228

Query: 382 KVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           +  EE+  + GD    + F++ L+ M Y   C+ E LRLY PVP + R++++ IT P +G
Sbjct: 229 RCREEIQSLLGDG---LCFREHLDQMPYTTMCIKEALRLYLPVPTVGRELSKPITFP-DG 284

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNK-------------------FDPDNFLPERSAN 481
           + +P G  ++++ Y LH   +V+PNP                     FDP  F P+  A+
Sbjct: 285 RSLPRGFLVLLSFYALHHNSNVWPNPEVERKEELDHTYPGPGVPLQVFDPSRFAPD--AS 342

Query: 482 RHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 523
           RH +AF+PFS G R+C+G+ +AM ++KV ++  L  F +  D
Sbjct: 343 RHSHAFLPFSGGSRNCIGQHFAMKEMKVAVALTLLRFELAPD 384



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 21/86 (24%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV----DKLKKEASNFDCH 186
           G GLL+  G+ W  HR+++ P FH ++LK ++ L   + + ++    ++L  + S+ +  
Sbjct: 71  GYGLLLLNGEIWFQHRRMLTPAFHYDILKPYVRLMVDSVQVMLVNKWEELLSQNSHLEIF 130

Query: 187 DYMSECTVEILLETAMGVSKSTQDQS 212
           +++S  T++ +++ A   S   ++ S
Sbjct: 131 EHVSLMTLDTIMKCAFRPSDQAEEGS 156


>UniRef50_UPI0000F21E21 Cluster: PREDICTED: similar to cytochrome
           P450 CYP4F13; n=1; Danio rerio|Rep: PREDICTED: similar
           to cytochrome P450 CYP4F13 - Danio rerio
          Length = 328

 Score =  146 bits (353), Expect = 2e-33
 Identities = 67/184 (36%), Positives = 112/184 (60%), Gaps = 2/184 (1%)

Query: 339 GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD-RP 397
           G  +++EEIK   D  MF GHDTTA+  S+    + ++QD Q++   E+  +  D D   
Sbjct: 116 GEGLTNEEIKAHADMFMFAGHDTTASALSWIFYNLAMNQDYQERCRAEVRDLLADRDTHT 175

Query: 398 VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLH 457
           + ++D  ++ +   C+ E+LRL+ PV  + R  +Q +  P +   IP G   +I+ Y +H
Sbjct: 176 IGWEDLSQLTFTTMCIKESLRLHSPVLALTRYYSQNMKTPGDCV-IPHGCLCLISIYGVH 234

Query: 458 RRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRN 517
           R P V+P+P  FDP  F P  S +R  +AF+PFSAGPR+C+G+ +AM ++KV+++  L  
Sbjct: 235 RNPQVWPDPLVFDPTRFDPHNSDSRSPHAFIPFSAGPRNCIGQNFAMAEMKVVVALTLAR 294

Query: 518 FRVI 521
           F+++
Sbjct: 295 FKIL 298



 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 31/86 (36%), Positives = 53/86 (61%), Gaps = 3/86 (3%)

Query: 92  WIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 148
           ++GP   +V L+ P  +  +L++   I   +   Y F KPWLGN LL+ +GQ+W  HR+L
Sbjct: 28  FLGPFYNMVRLFHPDYIRSLLTASASITLKDRIFYGFMKPWLGNCLLLQSGQEWSRHRRL 87

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVD 174
           + P FH ++LK ++ +FN ++  + D
Sbjct: 88  LTPAFHFDILKKYVHIFNQSTNIMHD 113


>UniRef50_UPI0000D55FA3 Cluster: PREDICTED: similar to Cytochrome
           P450 4g15 (CYPIVG15); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4g15 (CYPIVG15) -
           Tribolium castaneum
          Length = 193

 Score =  145 bits (351), Expect = 3e-33
 Identities = 74/174 (42%), Positives = 110/174 (63%), Gaps = 3/174 (1%)

Query: 354 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 413
           ++F G  + A    + L M+ IH +IQ+K+ EEL  IFG+SDR + F+D  ++ YL+R +
Sbjct: 1   MVFTGSGSLAITECYVLLMLAIHPEIQEKIYEELLTIFGNSDRDLCFKDLSKLCYLDRVI 60

Query: 414 METLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDN 473
            ETLRL+P  P IAR ++ +I +      IP GT  +I    L R  +++  P +FDPD 
Sbjct: 61  KETLRLFPIAPYIARLLDSDIHMEKY--VIPKGTFALIPITYLQRNSNLWSEPLRFDPDR 118

Query: 474 FLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKES 527
           FLPE+ A R    ++PFS G R+C+G KYA + LK  L+TILR ++ +S L+ES
Sbjct: 119 FLPEQVATRERCVYLPFSYGSRNCIGLKYAEISLKATLATILRKYKYVS-LRES 171


>UniRef50_A7RNE6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 498

 Score =  145 bits (351), Expect = 3e-33
 Identities = 72/192 (37%), Positives = 108/192 (56%), Gaps = 2/192 (1%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           L  +++    G+ +  EE+ +   T    G +TTA   SF L  +G+H DI  KV+EE+D
Sbjct: 280 LSTIMKLELQGLELDIEELLDDFVTFFIAGQETTANQLSFALLEIGLHPDITHKVVEEVD 339

Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448
           ++ G     V + D   + Y+ + L ETLR YPP   + R   +EITL  NG  IPAGT 
Sbjct: 340 KVIGSHVDFVEYDDLANLSYMTQVLKETLRKYPPAAGVIRHSPEEITL--NGHVIPAGTG 397

Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508
           + +  Y  H  P  + +P  FDP+ F  E + N   + F+PFS GPRSC+G+ +A  + K
Sbjct: 398 IGLNIYGAHHNPTNWKDPEVFDPERFNAENAPNIKPFTFLPFSLGPRSCIGQHFAQFEAK 457

Query: 509 VILSTILRNFRV 520
           V+L+  L+ FR+
Sbjct: 458 VLLARFLQKFRI 469


>UniRef50_A7SJV6 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 512

 Score =  144 bits (350), Expect = 4e-33
 Identities = 73/210 (34%), Positives = 117/210 (55%), Gaps = 3/210 (1%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           +SD+EI  Q  T +  G++TT+   +F   ++ ++ D QD++IEE+D++         + 
Sbjct: 305 LSDDEIVAQCFTFILAGYETTSNTMAFTSYLLALNPDKQDRLIEEIDEVAATVGDNFDYD 364

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
             L M+YLE  + E LRLYPP     R  NQ  T+  NG+  P G  ++I  + +HR P+
Sbjct: 365 TVLGMEYLEMVVQEALRLYPPGFRFGRTCNQSCTI--NGQFFPKGCIVLIPVFAMHRDPE 422

Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 520
           ++P P KF P+ F  E    RH YA +PF  GPR+C+G ++A+L+ K+ L  ILR +R+ 
Sbjct: 423 IWPEPEKFQPERFTAEAKQARHPYAHLPFGGGPRNCIGMRFALLEAKMALVYILRYYRLE 482

Query: 521 ISDLKESDFKLQADIILKRAEGFQVRLQPR 550
                E   +LQ  I +    G  +++  R
Sbjct: 483 RCPETEVPVQLQGTITISPKHGIYLKITKR 512



 Score = 44.4 bits (100), Expect = 0.008
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 5/123 (4%)

Query: 92  WIGPRLLVFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149
           ++G R  + + DP   + IL      ++++        P     LL      WR  R  I
Sbjct: 84  YMGTRAAILVADPEMAKQILVKEFDKFVNRPIVQSAQTPPTDKTLLSLQDDDWRRLRHTI 143

Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVSK 206
            PTF    LK  + L N + R +V+KL    K+  + D      + T+E ++ TA G+  
Sbjct: 144 TPTFSAVKLKQVLPLINESCRILVEKLGEACKDGKSVDVLRSYGKFTMETIVTTAFGIDC 203

Query: 207 STQ 209
            TQ
Sbjct: 204 QTQ 206


>UniRef50_UPI0000D56428 Cluster: PREDICTED: similar to Cytochrome
           P450 4g1 (CYPIVG1); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4g1 (CYPIVG1) -
           Tribolium castaneum
          Length = 713

 Score =  144 bits (349), Expect = 5e-33
 Identities = 72/174 (41%), Positives = 106/174 (60%), Gaps = 7/174 (4%)

Query: 349 EQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKY 408
           E+   + F G +T+    S  L ++G+   IQ+K+  E+DQ+FG S    T  +   + Y
Sbjct: 269 EEAQIMFFVGTETSGVAISSVLLILGMFPQIQEKIFIEIDQVFG-STTGSTLDEINHLDY 327

Query: 409 LERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNK 468
           LER + ETLRL PP+P + R +++ + L       PAG+ +++    +HRR D +P P K
Sbjct: 328 LERVIKETLRLLPPIPFVMRSLDENLKLSCG--TFPAGSRVIVPIMMVHRREDFWPEPLK 385

Query: 469 FDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 522
           FDPD FL ER +      ++PFS G R+C+G KYAML +KVIL+TILR +RV S
Sbjct: 386 FDPDRFLEERPSG----TYIPFSYGTRNCLGYKYAMLSMKVILATILRKYRVKS 435



 Score = 79.8 bits (188), Expect = 2e-13
 Identities = 51/165 (30%), Positives = 78/165 (47%), Gaps = 4/165 (2%)

Query: 85  HESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRS 144
           +  VVKIW GP L V   +P D++VIL+ H  +DK E Y     +    L  +    W+ 
Sbjct: 63  YPKVVKIWFGPWLYVSTTEPSDLKVILTHH--LDKGEFYELMSEYFRRALAAAPVDLWKK 120

Query: 145 HRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGV 204
           HRK I PTF+  +L +FI  F   +  +V  L+K  S+ D    + +CT++   ET   V
Sbjct: 121 HRKNINPTFNTTILNTFIGAFAKQAEILVKNLEKYQSDEDIFPIVWKCTLDSACETLADV 180

Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAK 249
                D         V ++ +IL  R        ++L+KF+   K
Sbjct: 181 DPIFIDTEA--CLRRVFRIEEILLERFFNPLCHLNILWKFSPLRK 223


>UniRef50_Q6SPQ5 Cluster: CYP342A1; n=1; Nereis virens|Rep: CYP342A1
           - Nereis virens (Sandworm)
          Length = 508

 Score =  144 bits (349), Expect = 5e-33
 Identities = 69/193 (35%), Positives = 119/193 (61%), Gaps = 5/193 (2%)

Query: 332 LLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIF 391
           LLE     V + D EI+++VDT MFEGHDTTA+G S+ L  +  H ++Q++  +E+ ++ 
Sbjct: 317 LLEMRTEKVCL-DREIRDEVDTFMFEGHDTTASGISWILYELSGHPEVQEQAGQEVIRVI 375

Query: 392 G-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450
           G  SD  + + D   + YL +C+ E +R++PPVP I RQ++Q+I +  NG  IP  T   
Sbjct: 376 GSQSDGTIEWSDLSRLPYLSQCIKEAMRVHPPVPFIGRQLSQDIII--NGCTIPKDTICE 433

Query: 451 IATYKLHRRPDVYPNPN-KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKV 509
           ++ Y +H  P+V+   + +F P+ F P+   ++  + ++PFSAG R+C+G+ +A+ + KV
Sbjct: 434 VSIYGVHHNPEVWGKDHMEFKPERFHPDNMKDKDAFDYIPFSAGSRNCIGQNFALNEEKV 493

Query: 510 ILSTILRNFRVIS 522
           ++       R+ S
Sbjct: 494 VIRQGFAEVRITS 506



 Score = 48.8 bits (111), Expect = 4e-04
 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 7/99 (7%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGP-RLLVFLYDPRDVE---VILSSHVY 116
           N  +F G   ++F  +  K   Y  +   + W+GP   ++ L  P   +    ++ + V+
Sbjct: 76  NLSDFPGPGPEVFGWVQGKVNQY--KKFYQFWVGPFSPMISLCHPETSQNHPEVIRTKVH 133

Query: 117 IDKAEEYRFF-KPWLGNGLLISTGQKWRSHRKLIAPTFH 154
           + +        K WLG+GLL+S+G KW  +R+L+ P FH
Sbjct: 134 LHRIWPVMLLLKEWLGDGLLLSSGSKWFRNRRLLTPAFH 172


>UniRef50_UPI0000E4657A Cluster: PREDICTED: similar to cytochrome
           P450 3A27; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to cytochrome P450 3A27 -
           Strongylocentrotus purpuratus
          Length = 460

 Score =  144 bits (348), Expect = 7e-33
 Identities = 117/434 (26%), Positives = 200/434 (46%), Gaps = 38/434 (8%)

Query: 130 LGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVD---KLKKEASNFDCH 186
           L  G+L +  ++WR  R L++P+F    LKS + L    +  +VD   K ++E    +C 
Sbjct: 48  LAGGMLAAKDERWRKLRSLLSPSFTSVKLKSMVPLMRECAEVLVDIFTKREEEGKTIECK 107

Query: 187 DYMSECTVEILLETAMGV---SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFK 243
           +      ++++   A G+   S++ QD+   +YA        I +   T       +LF 
Sbjct: 108 ELYGPYAMDVIGSCAFGLRVNSQTNQDEPFIKYAKR------IFNFNVTNPAFLISMLFP 161

Query: 244 FTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLS 303
           +T    N  KL     G   K I    E+F  G     + +     +  TGK   +E + 
Sbjct: 162 WTAPIFNFFKL-----GSVPKDI----EQFFLGVFEKAIADRQANGD--TGKSDFLELMM 210

Query: 304 FGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESS---QSGVAISDEEIKEQVDTIMFEGHD 360
               S  K           +  +A  DL  E+S   +   A++ +EI     T +  G++
Sbjct: 211 ----SAHKEDDDVNIMNDAEDDIA--DLAQETSWKPKQKTALNRQEIIGNSITFLLAGYE 264

Query: 361 TTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLY 420
           T++    F   ++  +Q +QD ++ E+ ++   S   VTF+   +M+YL   +ME +R+Y
Sbjct: 265 TSSTALGFVSYLLATNQHVQDLLVAEVKEM-APSQSDVTFETVTKMEYLNMVIMEAMRIY 323

Query: 421 PPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSA 480
           PP  ++ R  N+EIT   N   I  G  + I  + L    D++P+P  FDP+ F  +R  
Sbjct: 324 PPGEVLERVCNKEITY--NNITIKKGQYIFIPIWNLQHDSDLWPDPETFDPERFSKDRRG 381

Query: 481 NRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDF--KLQADIILK 538
           N H   ++PF  GP +C+G ++AML++KV +  IL+ FR      E++   KL     L 
Sbjct: 382 NNHPCGWLPFGIGPHTCIGVRFAMLEIKVAMVCILQKFR-FDTCPETEIPPKLGNLSFLT 440

Query: 539 RAEGFQVRLQPRKR 552
              G  +R+ P  R
Sbjct: 441 PPNGITLRITPHSR 454


>UniRef50_Q06GC7 Cluster: Cytochrome P450; n=1; Rhodococcus sp.
           NS1|Rep: Cytochrome P450 - Rhodococcus sp. NS1
          Length = 497

 Score =  142 bits (344), Expect = 2e-32
 Identities = 73/216 (33%), Positives = 126/216 (58%), Gaps = 7/216 (3%)

Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396
           ++G  +SD+ I+ QV T +  GH+TTA   SF L  + ++ +I ++  EE++Q+ G    
Sbjct: 284 ETGEMMSDQSIRNQVLTFLIAGHETTAGLLSFALHYLSLNPEIVERAREEIEQVLGTDGA 343

Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456
           PV F+   +++Y+ R + ETLRL+P  P   R+  Q  TL  +G  I  G T+++    L
Sbjct: 344 PVRFEQVAKLRYVRRIIDETLRLWPSGPAFFRKARQATTL--DGYPIRKGETILVVLLAL 401

Query: 457 HRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515
           HR P ++  +P +FDPD FLP     R  +A+ PF  G R+C+GR++A+ +  + L+ IL
Sbjct: 402 HRDPALWGEDPERFDPDRFLPAAVRARPAHAYKPFGVGARACIGRQFALHEAVLALAQIL 461

Query: 516 RNFRVISDLKESDFKLQADIILK-RAEGFQVRLQPR 550
             F ++     +D++L  + +L  R E  ++ ++PR
Sbjct: 462 TRFDIV---PTADYELTVEELLTIRPENLKLAMRPR 494


>UniRef50_Q16L53 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 488

 Score =  142 bits (343), Expect = 3e-32
 Identities = 79/214 (36%), Positives = 127/214 (59%), Gaps = 9/214 (4%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           F+D LL   + G + S+ +I   V T++  G+DT+    ++    +G++  IQ+KV  E+
Sbjct: 276 FVDQLL---RLGNSFSETDIIHNVFTMIIAGNDTSGQLMAYACLFLGMYPHIQEKVHAEI 332

Query: 388 DQIFG-DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
            +I     + P++ +    + Y E  L E LRL P  P I RQ    ITL     +IPAG
Sbjct: 333 VEIIPRHHNEPISPEKLKSLAYTEMFLNECLRLCPTAPNIVRQNMAPITLDET--RIPAG 390

Query: 447 TTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505
             L I+ +  HRR D++ P+ ++FDPD F  ERSA RH +AF+PFS G R+C+G +YAM+
Sbjct: 391 NLLAISLFAYHRRKDIWGPDADEFDPDRFSAERSAGRHPFAFLPFSGGSRNCIGWRYAMI 450

Query: 506 KLKVILSTILRNFRVISDLKESD--FKLQADIIL 537
            +K++L  +LR F++ +D++  D  F+  A ++L
Sbjct: 451 SMKLMLVYLLREFKIKTDIRHQDMAFRFNAALVL 484



 Score = 88.6 bits (210), Expect = 4e-16
 Identities = 49/184 (26%), Positives = 97/184 (52%), Gaps = 5/184 (2%)

Query: 90  KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149
           K+W+GP + + +  P  V+++L+    ++K   YRF +  +  GLL++  + W+ HRK++
Sbjct: 77  KVWLGPVVCLGVCHPDLVQIVLTHPDCLEKPFIYRFIR--INRGLLVAEAELWKRHRKVL 134

Query: 150 APTFHLNVLKSFIDLF-NANSRAVVD-KLKKEASNFDCHDYMSECTVEILLETAMGVSKS 207
              F+L +L  FI +F    SR V D K  K+   FD   + + CT+E++ ET++G    
Sbjct: 135 NSAFNLRILHGFIPIFEKCCSRMVSDLKQMKDGETFDVMRFTARCTLEMVFETSLGTGCL 194

Query: 208 TQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIK 267
              +S       + +  +I   R   + L  + +F+ T  +K +T+ L   + + K+++ 
Sbjct: 195 PPSESDC-LIRHIKRFFNIASSRFLNVHLHYEPIFRLTQRSKKETESLHYCNTVVKQLLT 253

Query: 268 RKKE 271
            K++
Sbjct: 254 EKRQ 257


>UniRef50_Q179B9 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 506

 Score =  141 bits (342), Expect = 4e-32
 Identities = 74/225 (32%), Positives = 131/225 (58%), Gaps = 5/225 (2%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           +D LL  S  G   +D +I++ V  ++    DTT+  ++     +  + DIQ+++  EL 
Sbjct: 276 VDQLLGVSHDGRQFNDIQIRDNVYAVITGATDTTSLATAHACLFLSFYPDIQERLHAELA 335

Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448
           ++F  +    T ++  ++ YL+  + E  R    VP +AR+   EI +  +G K+P G  
Sbjct: 336 EVFPGNIADYTPENIKKLTYLDMFINEVQRHCTVVPYVARENTAEIEI--DGVKVPPGNI 393

Query: 449 LVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507
            +++ Y +H+RPD++ P+  KFDP+NF  ER  +RH  AF+P+SAG ++C+G +YA+  +
Sbjct: 394 FIMSLYAMHKRPDIWGPDAEKFDPENFTEERIKDRHPAAFLPYSAGSKNCLGWRYAIFGM 453

Query: 508 KVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552
           K+I+  ++RNF   S +K  D + + D+ LK    FQ  +Q +KR
Sbjct: 454 KLIMIHLVRNFHFSSKIKHEDMQFRHDLTLKLP--FQHLVQLKKR 496



 Score = 51.2 bits (117), Expect = 7e-05
 Identities = 55/255 (21%), Positives = 103/255 (40%), Gaps = 11/255 (4%)

Query: 20  LFYVLLVPAVILWYAYWRMSRRRLYELADKL-NXXXXXXXXXNALEFVGGSADIFRNIVQ 78
           +F+  +     LWY  +R      ++ ADK  +         NAL  +  + D+ R    
Sbjct: 5   VFFGTIATLGTLWYWTYRWQ----FKFADKWPSVRPRYAIVGNALIMLWKN-DVQRFQEI 59

Query: 79  KSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLIST 138
           K    + + ++  W GP++ +    P  V  ILSS   +++   YRF       G+  + 
Sbjct: 60  KRVFSECDRILTAWAGPKMFLITSHPDIVHQILSSPDCLERPFLYRF--AGFTQGIFTAK 117

Query: 139 GQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEI 196
              W+ +RK +  TF+  ++  F+  F      +   L +  +    +   Y + C +E+
Sbjct: 118 LPVWKDNRKRLNSTFNQRIVHGFVPYFVKCCEKMTKSLLECADGETVNIQKYTAVCALEM 177

Query: 197 LLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLD 256
              T +G     Q     E+   +    +    R   +    DL+++ T + K   +   
Sbjct: 178 AAGTTLGGDVLQQGDGKEEFKRGLDLAFNGASRRMVTVPFYSDLIYQMTHHYKELMEGRR 237

Query: 257 II-HGLTKKVIKRKK 270
           II    TK +I+RKK
Sbjct: 238 IICDFFTKLLIERKK 252


>UniRef50_A7SXR0 Cluster: Predicted protein; n=5; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 481

 Score =  141 bits (342), Expect = 4e-32
 Identities = 75/219 (34%), Positives = 123/219 (56%), Gaps = 4/219 (1%)

Query: 321 GQKKRLAFLDL-LLESSQSGVA-ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378
           G+KK L  L L   E +  GV  ++D+E+  Q  T +  G +TT    +    ++  H D
Sbjct: 251 GRKKDLVTLMLEAREDTVDGVPRLNDQELAAQSLTFLLAGFETTTNTLANTAYLLARHPD 310

Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438
           +QDK+I+ELD    +      ++ + ++ YL+R + E+LRLYPP  +I R+ ++E T+  
Sbjct: 311 VQDKLIQELDLAGSNRGNSPLYEYSQKIDYLDRVINESLRLYPPGYLIIRRYDEECTI-- 368

Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
            G   P G  + I  Y LHR P V+  P+ FDP++F  E +  RH Y+F+PF  GPR C+
Sbjct: 369 QGVHFPRGVDVNIPVYILHRDPAVWERPDDFDPEHFSHEANEKRHPYSFIPFGMGPRQCI 428

Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIIL 537
           G ++A++++K+ L  IL  ++  S  +  D      +IL
Sbjct: 429 GMRFALMEIKIALVNILEKYKFCSSEETQDLLEHRAVIL 467



 Score = 51.6 bits (118), Expect = 5e-05
 Identities = 44/199 (22%), Positives = 88/199 (44%), Gaps = 18/199 (9%)

Query: 88  VVKIWIGPRLLVFLYDPRDVE--VILSSHVYIDKAEEYRFFKPW--LGNGLLISTGQKWR 143
           V K++IG    + + DP  V+  VI   H + ++     F KP   + +G+ +  G  W+
Sbjct: 65  VHKMFIGRAPAIVVSDPEIVKQIVIKEFHKFPNRP---LFIKPNPPMDSGMFLGQGALWK 121

Query: 144 SHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMG 203
             R  + PTF    LK  + + ++    +  +  + + + DC +  S   ++++  +A G
Sbjct: 122 RIRTTLTPTFSTAKLKQIVPIIDSRKWPLSPQQVERSESTDCVNLFSLFALDVITISAFG 181

Query: 204 VSKSTQ-DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLL---DIIH 259
           V    Q D     Y +A            T IW+R   +F F++Y      +L   D   
Sbjct: 182 VETDIQTDPDSSFYKLAKKAF-------RTPIWVRAFSMFPFSEYLSKYVHVLPNIDYFL 234

Query: 260 GLTKKVIKRKKEEFASGKK 278
            +   +++++K+  + G+K
Sbjct: 235 KIALSMVEQRKKHGSQGRK 253


>UniRef50_Q8UF31 Cluster: Cytochrome P450; n=1; Agrobacterium
           tumefaciens str. C58|Rep: Cytochrome P450 -
           Agrobacterium tumefaciens (strain C58 / ATCC 33970)
          Length = 464

 Score =  140 bits (340), Expect = 7e-32
 Identities = 74/230 (32%), Positives = 126/230 (54%), Gaps = 7/230 (3%)

Query: 329 LDLLLESS--QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           + +LLE+   ++G  +SDEEI + + T +  GH+TTA G ++   ++  + + + K +EE
Sbjct: 239 VSMLLEAKDPETGRMMSDEEIIDNLLTFITAGHETTALGLAWTFHLLSQNPETERKAVEE 298

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           ++ + G    PV  +    + Y+ +   E +RLYPP P+I R   Q+  L  +   IPAG
Sbjct: 299 IEAVTGGE--PVAAEHIANLAYVRQVFSEAMRLYPPAPVITRTALQDFRLGEHD--IPAG 354

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
           T L +  Y +HR   ++  P +FDP  F PE+   RH YA++PF AGPR C+G  +AM++
Sbjct: 355 TVLYVPIYAVHRHTALWDEPERFDPSRFEPEKVKARHRYAYMPFGAGPRVCIGNAFAMME 414

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRMAKA 556
              IL+ IL+   + +    S   L   + L+  E   +++  R+  + A
Sbjct: 415 AVAILAVILQKNHLENRTMASAEPLMR-VTLRPQERLMMKITQRQNKSPA 463



 Score = 42.3 bits (95), Expect = 0.032
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 7/138 (5%)

Query: 86  ESVVKIWIGPRLLVFLYDPRDV-EVILSSHVYIDKAEEYR-FFKPWLGNGLLISTGQKWR 143
           E  V   +G  + V L DP  + E ++ +   + K E+ R    P LG GLL + G  W+
Sbjct: 46  EPAVFTRLGGVMRVHLADPVLIHEALVKNAALLGKGEDVRRALGPALGQGLLTADGDHWK 105

Query: 144 SHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA-SNFDCHDYMSECTVEILLETAM 202
             R+ +A  F    L   + +    +R    + +  + ++ D    M   T +I++ET M
Sbjct: 106 WQRQSVAAAFRHEKLLELLPVMIETARRTQKRWRSSSTADIDIGHEMMRTTFDIIVETMM 165

Query: 203 ----GVSKSTQDQSGFEY 216
               G+  +  +QS  +Y
Sbjct: 166 SGGYGIDIARVEQSITDY 183


>UniRef50_Q8T632 Cluster: Cytochrome P450 CYP6P3; n=42; Diptera|Rep:
           Cytochrome P450 CYP6P3 - Anopheles gambiae (African
           malaria mosquito)
          Length = 509

 Score =  140 bits (340), Expect = 7e-32
 Identities = 64/180 (35%), Positives = 103/180 (57%)

Query: 340 VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVT 399
           V ++  E+  Q       G +T++   SF L  +  + DIQ+++ EE+++   ++   VT
Sbjct: 297 VGMTQNELAAQAFVFFLAGFETSSTTQSFCLYELAKNPDIQERLREEINRAIAENGGEVT 356

Query: 400 FQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 459
           +   + +KYL+  + ETLR YPPV  + R  + +  +P     IP  T + I  Y + R 
Sbjct: 357 YDVVMNIKYLDNVIDETLRKYPPVESLTRVPSVDYLIPGTKHVIPKRTLVQIPAYAIQRD 416

Query: 460 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519
           PD YP+P +F+PD FLPE    RH + F+PF  GPR C+G ++ +++ KV L T+LR FR
Sbjct: 417 PDHYPDPERFNPDRFLPEEVKKRHPFTFIPFGEGPRICIGLRFGLMQTKVGLITLLRKFR 476


>UniRef50_Q86GR1 Cluster: Cytochrome P450 CYPm3r5; n=12;
           Culicidae|Rep: Cytochrome P450 CYPm3r5 - Anopheles
           gambiae (African malaria mosquito)
          Length = 519

 Score =  140 bits (340), Expect = 7e-32
 Identities = 75/236 (31%), Positives = 127/236 (53%), Gaps = 13/236 (5%)

Query: 324 KRLAFLDLLLESSQSGVA---------ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMG 374
           +R  FLDLL+    +G           +S +EI  Q       G +T+++  ++ L  + 
Sbjct: 273 RRNDFLDLLIRLKNTGSLEGSHEIVGRLSGDEIAAQAFIFFTAGFETSSSAMTYTLYELA 332

Query: 375 IHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEI 434
           ++Q+ Q K  E + +     D  V+++ +  M YL++C+ ETLR YPPV I+ R V +  
Sbjct: 333 LNQEAQRKARECVLEALAKHDGVVSYESSKNMLYLDQCIYETLRKYPPVAILERIVTKPY 392

Query: 435 TLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGP 494
            +P     +  G  ++I  Y +H  PD+YP P  +DPD F PER A R   A++PF  GP
Sbjct: 393 RIPDTSVTLHPGMKIMIPAYAIHHDPDIYPEPATYDPDRFTPERMARRDPCAYLPFGEGP 452

Query: 495 RSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD---IILKRAEGFQVRL 547
           R C+G ++ M++ ++ L+ +L++F+V+   KE+D  L       +L    G ++RL
Sbjct: 453 RICIGLRFGMMQARIGLALLLKHFQVL-PCKETDVPLTYSPRAFVLTPVNGVRLRL 507


>UniRef50_Q89R90 Cluster: Blr2882 protein; n=4; Bacteria|Rep:
           Blr2882 protein - Bradyrhizobium japonicum
          Length = 1078

 Score =  140 bits (339), Expect = 9e-32
 Identities = 75/215 (34%), Positives = 121/215 (56%), Gaps = 4/215 (1%)

Query: 338 SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG-DSDR 396
           +G  + D  I+ Q++T +  GH+TT+   S+ L  +  H DI  K  +E+D++FG D + 
Sbjct: 252 TGEQLDDVNIRYQINTFLIAGHETTSGLLSYTLYALLKHPDILKKAYDEVDRVFGPDVNA 311

Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456
             T+Q   ++ Y+ + L E LRL+PP P        + T+     K+  GT + I    L
Sbjct: 312 KPTYQQVTQLTYITQILKEALRLWPPAPAYGISPLADETIGGGKYKLRKGTFITILVTAL 371

Query: 457 HRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515
           HR P V+ PNP+ FDP+NF  E  A R   A+ PF  G R+C+GR +AM +  + L  IL
Sbjct: 372 HRDPSVWGPNPDAFDPENFSREAEAKRPINAWKPFGNGQRACIGRGFAMHEAALALGMIL 431

Query: 516 RNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           + F++I D +     L+  + +K  EGF+++++PR
Sbjct: 432 QRFKLI-DHQRYQMHLKETLTMK-PEGFKIKVRPR 464


>UniRef50_A7D7T8 Cluster: Cytochrome P450; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Cytochrome P450 -
           Halorubrum lacusprofundi ATCC 49239
          Length = 469

 Score =  140 bits (338), Expect = 1e-31
 Identities = 71/222 (31%), Positives = 125/222 (56%), Gaps = 7/222 (3%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           L +LL +   G   +DE +++++ T++  GHDTTA   ++   ++  H + +++V  E  
Sbjct: 255 LSVLLRARDRGEQ-TDENLRDELVTMLLAGHDTTALALTYTFYLLSNHPEARERVAREAA 313

Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448
                +D P T  D  EMK+ ER L E+LRLYPPV  + R+   ++ L   G +IP G+ 
Sbjct: 314 A--ATADGPPTAADAREMKFTERVLNESLRLYPPVYTLFREPKLDVKL--GGYRIPEGSA 369

Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508
           L+++ + +HR P  Y +P  FDP  + PER + R  +AF PF  GPR C+G+ +++L+ K
Sbjct: 370 LMLSQWAIHRSPRWYDDPETFDPSRWEPERQSKRPRFAFFPFGGGPRHCIGKAFSLLEAK 429

Query: 509 VILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +IL+ +   + +  D +  D  L+  + +       +R++ R
Sbjct: 430 LILAEVCSRYDL--DYEGPDLSLRGSLTMHPDHPVPMRIRER 469



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 2/69 (2%)

Query: 88  VVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYR--FFKPWLGNGLLISTGQKWRSH 145
           VV+  +GPR    L +P DVE +L +     +  ++        LGNGLL+S G+ W   
Sbjct: 38  VVRFDLGPRETYMLTNPADVERVLVADAERYRKPDFGDDAIDTLLGNGLLMSEGETWERQ 97

Query: 146 RKLIAPTFH 154
           R+L +P+FH
Sbjct: 98  RRLASPSFH 106


>UniRef50_UPI00015B4AC4 Cluster: PREDICTED: similar to cytochrome
           P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 521

 Score =  139 bits (337), Expect = 2e-31
 Identities = 67/202 (33%), Positives = 110/202 (54%), Gaps = 5/202 (2%)

Query: 324 KRLAFLDLLLESSQSGV-----AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378
           KR  F+DLL+E    G       + +  I  Q       G++T++   +F L  + ++ +
Sbjct: 286 KRHDFMDLLIELKNRGTLELDNVLDENTIAAQAFVFFVAGYETSSNTIAFCLYELAVNPE 345

Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438
           IQ+K   ++       D  +T+    +MKYL+  ++ETLR YPP P+++R+      LP 
Sbjct: 346 IQEKARRDIIDALDKRDSKLTYDAVQDMKYLDMVILETLRKYPPAPLLSRRCEYPYKLPG 405

Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
           +  ++  G  +VI  Y +H  P  YP P+KF P+ F  E    RH Y F+PF  GPR+C+
Sbjct: 406 SDVELSKGMRVVIPIYAIHHDPKHYPEPDKFRPERFGDEEKRARHPYTFLPFGEGPRNCI 465

Query: 499 GRKYAMLKLKVILSTILRNFRV 520
           G ++A+L+ KV + T LR ++V
Sbjct: 466 GTRFALLQTKVGVITFLRKYQV 487


>UniRef50_Q82D73 Cluster: Putative cytochrome P450; n=2;
           Streptomyces avermitilis|Rep: Putative cytochrome P450 -
           Streptomyces avermitilis
          Length = 470

 Score =  139 bits (337), Expect = 2e-31
 Identities = 73/206 (35%), Positives = 114/206 (55%), Gaps = 4/206 (1%)

Query: 346 EIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD-SDRPVTFQDTL 404
           E++EQV   +  GH+TTA   +F L ++  H + Q +V +E D++ G    R  T  D  
Sbjct: 261 ELREQVLIFLLAGHETTATALAFALHLLARHPEQQRRVRDEADRVLGGPGGRAPTAADME 320

Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464
            + YL   L E +RLYP  P+I R+   +  +  +G +IPAG  L ++ +  HR PD +P
Sbjct: 321 ALPYLTMVLKEAMRLYPSAPVIGRRAVADAEV--DGVRIPAGADLFVSPWVTHRHPDYWP 378

Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDL 524
           +P +FDP+ F PE  A R  YA+ PF  GPR+C+G+  +ML+  + L+ ++R F     +
Sbjct: 379 DPERFDPERFTPEAEAGRPRYAWFPFGGGPRACIGQHLSMLESVLGLAVLIREFE-FEAV 437

Query: 525 KESDFKLQADIILKRAEGFQVRLQPR 550
            E +  L A I L      + R+ PR
Sbjct: 438 GEEEVPLGAGITLLAKGPARCRVIPR 463


>UniRef50_Q4U3Y5 Cluster: CYP325D1; n=1; Anopheles gambiae|Rep:
           CYP325D1 - Anopheles gambiae (African malaria mosquito)
          Length = 304

 Score =  139 bits (337), Expect = 2e-31
 Identities = 70/183 (38%), Positives = 112/183 (61%), Gaps = 4/183 (2%)

Query: 327 AFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           A LD LL  ++ G  +SD EI + + +I+  G+DTTA         + +H  +Q K+ +E
Sbjct: 125 AMLDRLLSVNEDG-PLSDTEIVQNIYSIVGAGNDTTAHSLGHTCLFLAMHPAVQRKLYQE 183

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           L  +F  +D P+T +   ++ Y+E  + E+LRL PP   +AR+  +++T+   G+ IP G
Sbjct: 184 LRDVFYSADEPITEEKLKQLSYMECVIKESLRLAPPGATVAREAQEDLTV--EGQLIPRG 241

Query: 447 TTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505
           TT+V++ + LHRR D +  +  +FDPD FL ER  NR   AF+PF+ G R+C+G +YAM 
Sbjct: 242 TTVVVSLFALHRRKDFWGADAERFDPDRFLSERCKNRMGCAFMPFNTGSRNCIGSRYAMQ 301

Query: 506 KLK 508
            +K
Sbjct: 302 IMK 304


>UniRef50_Q5U3Q3 Cluster: Cytochrome P450, family 3, subfamily c,
           polypeptide 1 like, 2; n=4; Danio rerio|Rep: Cytochrome
           P450, family 3, subfamily c, polypeptide 1 like, 2 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 494

 Score =  139 bits (336), Expect = 2e-31
 Identities = 71/218 (32%), Positives = 123/218 (56%), Gaps = 4/218 (1%)

Query: 335 SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDS 394
           S Q    ++D EI  Q    +  G++TT+   SF L  +  + D  +K++EE+D+ F   
Sbjct: 279 SEQPVKGLTDHEILSQSFIFILGGYETTSTTLSFLLHNLATNPDCLEKLVEEIDKNF-PL 337

Query: 395 DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATY 454
           D P+++   ++M YLE  + E++RL P  P + R   + + L  NG  IP  T + I TY
Sbjct: 338 DTPISYDALMKMDYLEMSINESMRLLPTAPRLERVCKKTVEL--NGITIPKDTLVAIPTY 395

Query: 455 KLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTI 514
            L+R P ++ +P +F P+ F PE  +    YAF+PF  GPR+C+G ++A++ +K+++  +
Sbjct: 396 VLNRDPQLWDSPQEFRPERFSPENKSEFLQYAFMPFGLGPRNCIGMRFALMIVKLLVVKL 455

Query: 515 LRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552
           L+NF  +   KE+   L+   + +      ++L PRKR
Sbjct: 456 LQNFS-LETCKETQIPLELTPVFQPKVPITLKLTPRKR 492


>UniRef50_Q9BID0 Cluster: Cytochrome P450; n=27; Culicidae|Rep:
           Cytochrome P450 - Anopheles gambiae (African malaria
           mosquito)
          Length = 501

 Score =  139 bits (336), Expect = 2e-31
 Identities = 58/178 (32%), Positives = 103/178 (57%), Gaps = 1/178 (0%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           I+ E++  Q       G +T++   SF L  + ++Q++QDK  + +  +       +T++
Sbjct: 291 ITIEDVAAQAFVFFLAGFETSSTAMSFCLYELALNQELQDKARQNITDVMKQHSS-ITYE 349

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
              EMKY+E C+ E++R YPP+  + R+V ++  +P   K +  G    I  Y LH  P+
Sbjct: 350 AVHEMKYIEMCINESMRKYPPITTLTRRVEKDYRVPDTDKVLQEGIMAAIPVYALHHDPE 409

Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519
            +PNP +FDPD F  E+ A RH + ++PF  GPR C+G ++ M++ ++ L  +L++FR
Sbjct: 410 HFPNPEQFDPDRFTAEQEAKRHPFVYLPFGEGPRICIGLRFGMMQARIGLVYLLKHFR 467


>UniRef50_Q7QH22 Cluster: ENSANGP00000012679; n=5; Cellia|Rep:
           ENSANGP00000012679 - Anopheles gambiae str. PEST
          Length = 526

 Score =  138 bits (335), Expect = 3e-31
 Identities = 63/188 (33%), Positives = 114/188 (60%), Gaps = 1/188 (0%)

Query: 333 LESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG 392
           L ++ +G A+S +E+  Q       G++T+++  +F L  + +++  Q++    + +   
Sbjct: 304 LRAASNGSALSMDELMAQAFGFFLAGYETSSSNVTFCLYELALNEHCQERARACVREALR 363

Query: 393 DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIA 452
                +T++   EM+YL+RC+ ETLR YPP+P++ R  ++   +P +   +PA   + + 
Sbjct: 364 KHGG-LTYEALGEMEYLDRCINETLRKYPPLPLLPRLTSKAYRIPGSDVILPAKMRIHLP 422

Query: 453 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 512
            Y + R    YP+P++FDPD F PER A RH+ AF+PF  GPR C+G++  +L+ ++ L+
Sbjct: 423 VYAIQRDERYYPDPDRFDPDRFAPERVAERHFSAFLPFGEGPRICIGQRLGVLQSRIGLA 482

Query: 513 TILRNFRV 520
           T+L NFRV
Sbjct: 483 TVLANFRV 490


>UniRef50_P05184 Cluster: Cytochrome P450 3A3; n=159;
           Euteleostomi|Rep: Cytochrome P450 3A3 - Homo sapiens
           (Human)
          Length = 504

 Score =  138 bits (335), Expect = 3e-31
 Identities = 73/220 (33%), Positives = 125/220 (56%), Gaps = 10/220 (4%)

Query: 322 QKKRLAFLDLLLES------SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGI 375
           QK R+ FL L+++S      ++S  A+SD E+  Q    +F G++TT++  SF +  +  
Sbjct: 265 QKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELAT 324

Query: 376 HQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEIT 435
           H D+Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ 
Sbjct: 325 HPDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVE 383

Query: 436 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495
           +  NG  IP G  ++I +Y LHR P  +  P KF P+ F  +   N   Y + PF +GPR
Sbjct: 384 I--NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 441

Query: 496 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 535
           +C+G ++A++ +K+ L  +L+NF      KE+   L+  +
Sbjct: 442 NCIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 480



 Score = 34.7 bits (76), Expect = 6.5
 Identities = 24/128 (18%), Positives = 57/128 (44%), Gaps = 7/128 (5%)

Query: 85  HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQ 140
           H+   K+W    G + ++ + DP  ++++L    Y        F    ++ + + I+  +
Sbjct: 65  HKKYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124

Query: 141 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 197
           +W+  R L++PTF    LK  + +       +V  L++E          D     +++++
Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184

Query: 198 LETAMGVS 205
             ++ GV+
Sbjct: 185 TSSSFGVN 192


>UniRef50_Q8WQN1 Cluster: Cytochrome P450 CYP4H24; n=23;
           Culicidae|Rep: Cytochrome P450 CYP4H24 - Anopheles
           gambiae (African malaria mosquito)
          Length = 193

 Score =  138 bits (334), Expect = 4e-31
 Identities = 65/191 (34%), Positives = 110/191 (57%), Gaps = 4/191 (2%)

Query: 362 TAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR--PVTFQDTLEMKYLERCLMETLRL 419
           T +G SF    +  H +IQ+K+  E+  + G   R  P+T+       YL+  + E+LRL
Sbjct: 4   TTSGISFTFYQLAKHPEIQEKLYREIQDVLGGEYRHVPLTYNTLQNFPYLDMVVKESLRL 63

Query: 420 YPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERS 479
            PPV  I R++  +I +  NG  IPAGT   I  Y +HR P VYP+P +FDP+ F    +
Sbjct: 64  LPPVSFIGRRLADDIEM--NGVTIPAGTDFTIPIYVIHRNPVVYPDPERFDPERFSDGNT 121

Query: 480 ANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKR 539
             R  Y ++PFS G R+C+G++YA+L++KV +  ++  +R++      + +L+ D++L+ 
Sbjct: 122 QRRGPYDYIPFSIGSRNCIGQRYALLEMKVAIVRMVSFYRILPGDTMHEIRLKTDLVLRP 181

Query: 540 AEGFQVRLQPR 550
            +   ++L  R
Sbjct: 182 DKSIPIKLVAR 192


>UniRef50_Q0IG08 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 526

 Score =  138 bits (334), Expect = 4e-31
 Identities = 108/407 (26%), Positives = 188/407 (46%), Gaps = 45/407 (11%)

Query: 130 LGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS--NFDCHD 187
           LGNGL+   GQKWR  R +++P F  N ++  + L    +  +   +++E     +D  +
Sbjct: 116 LGNGLISLEGQKWRDMRAMLSPMFTGNKIRHMVPLVGKCAEDLCRFVERETDEVEWDVRE 175

Query: 188 YMSECTVEILLETAMGVSKSTQDQSGFEY---AMAVMKMCDILHL-RHTKIWLRPDLLFK 243
            +++C VE++   A G+   + +    E+   A  +M   D+  + R   I + P +  +
Sbjct: 176 LLAKCLVEVIGSCAFGIEVDSFNDPDNEFDRVAKYLMNQSDVRKVARFLLIMVFPKMCKQ 235

Query: 244 FTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLS 303
           F        K   +   L  + + +++ +  S      L   A   +    K   VEG S
Sbjct: 236 F-GMELFDDKYKRLFRRLVSETMLKRESDGVSRPDLIQLLMLARRGKLEADK--DVEGES 292

Query: 304 FGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAIS--DEEIKEQVDTIMFEGHDT 361
           F  ++                        LE+    V  S  D+E+  Q       G DT
Sbjct: 293 FAAAND----------------------YLETGTDDVKRSWSDDELTAQAVIFFAAGFDT 330

Query: 362 TAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYP 421
           T+   SF L  + IH +IQD++ EE+  +   SD  ++++    ++YL+  + E+LR +P
Sbjct: 331 TSTLLSFTLMELAIHPEIQDRLFEEIKSV-QRSDSVISYEQIQSLEYLDAVISESLRKWP 389

Query: 422 PVPIIARQVNQEITL--PSNGK---KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 476
           P+    R+  ++  +  P +G     I  G ++ +  Y  H  P  +PNP KFDPD F  
Sbjct: 390 PLTATDRKCTKDYLMVDPEDGSPMFSIEEGYSVWVPIYCFHHDPKYFPNPEKFDPDRF-- 447

Query: 477 ERSANRHYY---AFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520
               NRH     A++PF  GPR+C+G ++A++  K+IL  +LR+FRV
Sbjct: 448 -NRVNRHQLNPAAYMPFGVGPRNCIGSRFALMSAKMILLRLLRSFRV 493


>UniRef50_O76107 Cluster: Cytochrome P450; n=2; Culicini|Rep:
           Cytochrome P450 - Culex quinquefasciatus (Southern house
           mosquito)
          Length = 499

 Score =  138 bits (334), Expect = 4e-31
 Identities = 63/198 (31%), Positives = 115/198 (58%), Gaps = 4/198 (2%)

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           Q  R  F+DLL++   +    +  EI  Q       G++T++   +F L  + ++Q++Q+
Sbjct: 259 QASRKDFMDLLIKLEDN---FTFNEIAAQAFVFFQAGYETSSITMTFCLYELALNQELQE 315

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           +  + ++ +        +++   +M++L  C+ ETLR YPPV  + R++ +   +P    
Sbjct: 316 RARKSVEDVL-KRHGSFSYETIQDMEFLNCCVKETLRKYPPVANLFREITKNYKVPETDI 374

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            +  G  +VI  Y +H  PD+YPNP  F+P+ F+PE S NRH  A++PF  GPR+C+G +
Sbjct: 375 TLEKGYRVVIPVYGIHHDPDIYPNPEVFNPERFIPELSTNRHPMAYLPFGEGPRTCIGER 434

Query: 502 YAMLKLKVILSTILRNFR 519
           +A+++ K+ LS +L+ FR
Sbjct: 435 FALMETKIGLSRLLQKFR 452


>UniRef50_UPI00015B5073 Cluster: PREDICTED: similar to cytochrome
           P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 1350

 Score =  137 bits (332), Expect = 6e-31
 Identities = 67/196 (34%), Positives = 110/196 (56%), Gaps = 3/196 (1%)

Query: 358 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 417
           G +TTA+  ++ L  +  +QDIQ+++  E+ Q+   S   +T++    M YL+    ETL
Sbjct: 255 GQETTASAITYCLYELSFNQDIQEELYNEISQV-AHSPEGLTYEKLFSMPYLDMVFRETL 313

Query: 418 RLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPE 477
           R +P  P++ RQ +++  +P +   I  GT +VI    LH  PD+YP+P+KFDP  F  E
Sbjct: 314 RKHPGAPMLNRQASEDFVVPGSHFVIKKGTRIVIPIKALHADPDIYPDPDKFDPTRFTSE 373

Query: 478 RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV-ISDLKESDFKLQADII 536
             A RH + ++PF  GPR C+G++  +LK K+ L  +L N++  + D      +   D  
Sbjct: 374 NKAKRHAFTYIPFGEGPRHCIGKRLGILKPKIALFYLLLNYKFSVCDKTPIPLRYMTDYF 433

Query: 537 LKRAEGFQVRLQPRKR 552
           ++   G QV L+  KR
Sbjct: 434 VQVPAG-QVYLKVEKR 448



 Score = 35.9 bits (79), Expect = 2.8
 Identities = 35/179 (19%), Positives = 75/179 (41%), Gaps = 6/179 (3%)

Query: 99  VFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLN 156
           +FL DP  +++IL  H   + ++   Y   K  L  GL+    +KW+  R  ++PTF   
Sbjct: 20  LFLMDPELIQLILVKHFNSFYNRGTLYNESKDPLSTGLVRLYDEKWKRLRVKLSPTFTSG 79

Query: 157 VLKSFIDLFNA---NSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVSKSTQDQSG 213
            LK    L          V + +  ++   +  D  +  T++ +   A G +  +  Q  
Sbjct: 80  KLKLMYPLVKEICDELLRVYEDVLDKSDVVEIKDITNRFTIDCISSIAFGFNCDSLHQPD 139

Query: 214 FEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEE 272
            E+        D+  +     +  P L+  F    + + K+ +  + L +K++  ++++
Sbjct: 140 NEFLKYGKISNDLGRVFLIFSFFVPRLVSLF-PIPEKRKKVSEFFYDLFEKMVSHRRKD 197


>UniRef50_UPI0000D56468 Cluster: PREDICTED: similar to Cytochrome
           P450 4c3 (CYPIVC3); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 4c3 (CYPIVC3) -
           Tribolium castaneum
          Length = 421

 Score =  137 bits (332), Expect = 6e-31
 Identities = 62/156 (39%), Positives = 100/156 (64%), Gaps = 2/156 (1%)

Query: 344 DEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDT 403
           D  +++++  I+  G +++A   +  L ++GI+ ++Q K+  ELD IFGD +R  TF+  
Sbjct: 266 DSPVEDEIQNILITGSESSALALALVLVVLGIYPEVQQKIALELDSIFGDDEREPTFEHI 325

Query: 404 LEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 463
            +M+YLE  + ETLR+ P VPII R   Q+I L      IPAG+T+++    + ++ + +
Sbjct: 326 NQMEYLECVIKETLRILPIVPIIMRLAEQDIKL--EHCTIPAGSTVLVPIVHISKKSEFW 383

Query: 464 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
             PNKF+PD FLP+ ++ RH   F+PFS GPR+CVG
Sbjct: 384 KEPNKFNPDRFLPKNNSERHRCTFLPFSYGPRNCVG 419



 Score = 92.7 bits (220), Expect = 2e-17
 Identities = 69/261 (26%), Positives = 119/261 (45%), Gaps = 19/261 (7%)

Query: 20  LFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQK 79
           L +VL +  V+ +   +  SRR LY    K++         +A  F+GG    ++ + Q 
Sbjct: 10  LIWVLFI-IVLYFLLKYNWSRRWLYYYGSKIDGPFAWPIIGSAHHFIGGQKVFYKKMTQI 68

Query: 80  SADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTG 139
              Y   ++ K W+G  L+V    P DVE++L+S    +K + Y++       GLLI+  
Sbjct: 69  FETYP--TLSKFWLGKDLIVITSRPEDVEIVLNS--CFEKPKFYKYAYKLFRTGLLIAPV 124

Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS-NFDCHDYMSECTVEILL 198
             W+  R++I PTF+   L++F ++F   +  +V  L++E    FD    +  CT    L
Sbjct: 125 NIWKERRRMIGPTFNSKTLQTFTEIFGKQANRLVRVLEQECGREFDIFLKLFRCT----L 180

Query: 199 ETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDII 258
           +TA G     QD     Y   +++  DI  +R    WL+ D  +K +   +   K     
Sbjct: 181 DTACG-----QD----NYLQKLIRAEDIATIRSFSPWLQVDFFWKKSPLGREMDKACAES 231

Query: 259 HGLTKKVIKRKKEEFASGKKP 279
               K+++  KK +F     P
Sbjct: 232 FTFIKQILSLKKCDFKDTTNP 252


>UniRef50_UPI0000D555E9 Cluster: PREDICTED: similar to Cytochrome
           P450 6a2 (CYPVIA2) (P450-B1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a2
           (CYPVIA2) (P450-B1) - Tribolium castaneum
          Length = 514

 Score =  137 bits (332), Expect = 6e-31
 Identities = 68/213 (31%), Positives = 118/213 (55%), Gaps = 2/213 (0%)

Query: 339 GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPV 398
           G +++ +E   Q       G +TT+   SF L  M  ++ I+ K   E++++ G     +
Sbjct: 300 GTSLTLDEAAAQAFIFFLAGFETTSTTISFALFEMARNESIRTKARTEINKVLGKHGGKL 359

Query: 399 TFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR 458
           T++ T+EM+YL+  + ETLR YPP P+  R+  +   +P     I  G +++I  Y LHR
Sbjct: 360 TYEATMEMEYLDTVISETLRKYPPAPVFLRKCTKTYRVPDTDVIIEEGLSVLIPAYGLHR 419

Query: 459 RPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518
            P+ +P+P  FDPD F  +  +    Y ++PF  GPR C+G ++AM+++K+ L+ IL++F
Sbjct: 420 DPEYFPDPETFDPDRFNEDNRSKIWDYTYIPFGDGPRICIGMRFAMIQIKIALALILKSF 479

Query: 519 RV-ISDLKESDFKLQ-ADIILKRAEGFQVRLQP 549
              +S+      K++ + IIL    G  + L P
Sbjct: 480 EFPLSEKTILPMKMENSGIILAPIGGIWLNLIP 512


>UniRef50_A5P357 Cluster: Cytochrome P450; n=1; Methylobacterium sp.
           4-46|Rep: Cytochrome P450 - Methylobacterium sp. 4-46
          Length = 463

 Score =  137 bits (332), Expect = 6e-31
 Identities = 72/233 (30%), Positives = 130/233 (55%), Gaps = 9/233 (3%)

Query: 321 GQKKRLAFLDLLLESS--QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378
           G + R   L LL+ +   +SG A+ D ++ + + T +  GH+TTA   ++ L ++ +H  
Sbjct: 235 GVEGRDDLLSLLVAARDPESGRAMDDRDVADNLLTFVTAGHETTALALAWTLYLLALHPA 294

Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438
           I+ +V+ E++ + G    P+       + +  + + E +RLYPP P++ R   +E+ +  
Sbjct: 295 IEARVVAEVEAVTGGG--PLAPHHVEALGFTRQAIQEAMRLYPPAPVLVRAALEEVDV-- 350

Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
            G +I  GT + +  Y +HR   ++  P++FDPD F PE +  R  YA++PF AGPR C+
Sbjct: 351 GGHRIGPGTPVTVPIYAIHRHALLWDEPDRFDPDRFAPEAAKARDRYAYLPFGAGPRICI 410

Query: 499 GRKYAMLKLKVILSTILRNFRVISDLKESDF-KLQADIILKRAEGFQVRLQPR 550
           G  +A+++   IL+ ++R+ R    L+      L+  I L+ AEG  +R+ PR
Sbjct: 411 GMSFALMEAVAILAVLIRDLRFA--LRPGFVPTLKQRITLRPAEGMPMRVAPR 461



 Score = 39.1 bits (87), Expect = 0.30
 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 4/111 (3%)

Query: 96  RLLVFLYDPRDVEVILSSHVY-IDKAEEYR-FFKPWLGNGLLISTGQKWRSHRKLIAPTF 153
           R  +F+ DP  V  +L       +K+E  R    P LG+ +L + G +WR  R+  AP F
Sbjct: 58  RATLFVMDPGLVRTVLVDRAESFEKSEVLRRSLSPALGDAILTADGARWRWQRRAAAPIF 117

Query: 154 HLNVLKSFIDLFNANSRAVVDKLK--KEASNFDCHDYMSECTVEILLETAM 202
               +  F+    A +    + LK     +  D    M   T +I+  T +
Sbjct: 118 RNERILGFLPAMIAAAERTREALKGLPPGTEADLAQVMMRTTFDIIAATML 168


>UniRef50_Q3E385 Cluster: Cytochrome P450; n=3; Chloroflexus|Rep:
           Cytochrome P450 - Chloroflexus aurantiacus J-10-fl
          Length = 452

 Score =  137 bits (331), Expect = 8e-31
 Identities = 73/232 (31%), Positives = 123/232 (53%), Gaps = 4/232 (1%)

Query: 289 SEPSTGKLTSVEGLSFGQSSGLKXXXXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIK 348
           S P+ G L     L   + +  +         G+   L  + +    + +G  +S ++I+
Sbjct: 193 SWPTPGNLQYRRNLELLERTVYRLIEERRQHQGEHDDLLEMLVTARDADTGEQMSPKQIR 252

Query: 349 EQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKY 408
           ++V TI   GH+TTA   S+ L ++  H + + K+  E   + G   R  T  D  ++ Y
Sbjct: 253 DEVMTIFLAGHETTAGTLSWILHLLAHHGESERKLRAEYATVLGG--RNPTPADLPQLPY 310

Query: 409 LERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNK 468
               + ETLRLYPP  I++R + +  TL     ++PAG  + ++ Y  HR PD +PN   
Sbjct: 311 NRMVIDETLRLYPPTWILSRVLVEADTL--GDYELPAGAVVALSPYVTHRHPDFWPNAES 368

Query: 469 FDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520
           FDP+ F P     RH +A++PF  GPR C+G  +A++++++IL  IL++FRV
Sbjct: 369 FDPERFRPTAIEQRHKFAYIPFITGPRQCIGNNFALMEMQLILPMILQHFRV 420


>UniRef50_Q9V4T3 Cluster: Probable cytochrome P450 4ad1; n=2;
           Sophophora|Rep: Probable cytochrome P450 4ad1 -
           Drosophila melanogaster (Fruit fly)
          Length = 516

 Score =  137 bits (331), Expect = 8e-31
 Identities = 77/203 (37%), Positives = 110/203 (54%), Gaps = 4/203 (1%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           GQ     FLD+LL +   G  + + EI E+V T +F GHD  AA  SF L  +  H +IQ
Sbjct: 269 GQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQ 328

Query: 381 DKVIEELDQIFGDSDRPVTFQDTL-EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
            K  EE  +IFG++         L +M YLE  + ETLRLYP VP+IAR     I +  N
Sbjct: 329 QKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDI--N 386

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNF-LPERSANRHYYAFVPFSAGPRSCV 498
           G K+   TT+++    +      + +P  F P+ F  P  +     +  VPFSAGPR C+
Sbjct: 387 GTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRCI 446

Query: 499 GRKYAMLKLKVILSTILRNFRVI 521
             K+AM ++K +LS +LR F ++
Sbjct: 447 AEKFAMYQMKALLSQLLRRFEIL 469



 Score =  110 bits (264), Expect = 1e-22
 Identities = 59/218 (27%), Positives = 111/218 (50%), Gaps = 4/218 (1%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120
           N  +F    A+  + ++Q    YD +    + +  +  + L DP +++ ILSS   + K 
Sbjct: 46  NLFQFGLKPAEYPKKVLQYCRKYDFQGFRSL-VFLQYHMMLSDPAEIQNILSSSSLLYKE 104

Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180
             Y F +PWLG+GLL S+G +W  H+KL AP F  + ++ ++ + +      V KL   +
Sbjct: 105 HLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLS 164

Query: 181 SN---FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLR 237
                FD  + +++CT++I+ E A G   S+ +    +   A+  +CD++  R   I  R
Sbjct: 165 DTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKR 224

Query: 238 PDLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFAS 275
            D LF+ T Y   Q + L ++     ++I +++ + A+
Sbjct: 225 FDALFRLTSYYMKQRRALSLLRSELNRIISQRRHQLAA 262


>UniRef50_Q3I414 Cluster: Cytochrome P450; n=18; Cucujiformia|Rep:
           Cytochrome P450 - Leptinotarsa decemlineata (Colorado
           potato beetle)
          Length = 510

 Score =  136 bits (330), Expect = 1e-30
 Identities = 65/210 (30%), Positives = 114/210 (54%), Gaps = 1/210 (0%)

Query: 334 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 393
           E +  G +++ +EI  Q       G +T++   +F L  +  H +IQ+KV  E++ +   
Sbjct: 290 EHTGDGTSLTMDEIVAQSFVFFIAGFETSSTTMTFALYQLATHPEIQEKVRSEINSVLEK 349

Query: 394 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIAT 453
            +  +T+    E+KY+ + + ETLR+YP +P++ R+  ++  +P +   I  G  + I  
Sbjct: 350 HNNQITYDALNELKYMGKVIDETLRMYPALPVVTRRCVEDYRIPDSDVIIEKGIEVFIPI 409

Query: 454 YKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILST 513
             +H  P+ Y NP  FDP+ F  E    RH YA +PF  GPR C+G ++ +++ KV L +
Sbjct: 410 KAIHYDPEYYENPEVFDPERFNEENIQGRHPYAHIPFGEGPRICIGLRFGVMQSKVGLVS 469

Query: 514 ILRNFRV-ISDLKESDFKLQADIILKRAEG 542
           IL+NFRV +S   +   K+  +  +   EG
Sbjct: 470 ILKNFRVTLSSKTKLPLKIDVNSFIPTTEG 499


>UniRef50_UPI0000D576F7 Cluster: PREDICTED: similar to Cytochrome
           P450 6a8 (CYPVIA8); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 6a8 (CYPVIA8) -
           Tribolium castaneum
          Length = 491

 Score =  136 bits (328), Expect = 2e-30
 Identities = 66/174 (37%), Positives = 100/174 (57%)

Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404
           EE+  Q       G +T+ A  SF L  +  HQDIQ KV EE   +    +  +T++   
Sbjct: 284 EEVASQCVLFFIAGFETSHATMSFALYELAKHQDIQQKVREEFWAVVDSQESEITYEAVQ 343

Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464
           ++KYL++ L ETLR YP V  + R+  ++  +P +G  I  GTT++I T  L+   + YP
Sbjct: 344 KLKYLDQVLNETLRKYPVVMYLTRRCIKDYKVPEDGAVIEKGTTVIIPTVALNYDENYYP 403

Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518
           NP KFDP  F  E    RH    +PF  GPR C+GR++A++++KV L  +L+N+
Sbjct: 404 NPKKFDPQRFSEENKKLRHPCIHLPFGLGPRFCIGRRFALIQVKVGLVLLLKNY 457


>UniRef50_Q0LLJ2 Cluster: Cytochrome P450; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Cytochrome P450 -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 459

 Score =  136 bits (328), Expect = 2e-30
 Identities = 66/221 (29%), Positives = 125/221 (56%), Gaps = 4/221 (1%)

Query: 331 LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390
           LL     +G  ++D++++++V T+   GH+TTA   ++   ++    +++ ++  E+D++
Sbjct: 232 LLSIDDGNGQGMTDQQVRDEVVTLFLAGHETTANTLTWCSYLLSQAPEVRQRLQAEVDEV 291

Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450
                RPVT QD  ++ Y E  + ETLR+YPP   ++ +V  E  +   G+ I      +
Sbjct: 292 L--QGRPVTLQDLQKLPYTEMVIKETLRMYPPAYALSARVPTE-NITVLGQTITPRQAAM 348

Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVI 510
           ++ Y +H  P  +P P +FDP+ F PE+   RH YA++PF AG R C+G  +AM++ +++
Sbjct: 349 VSPYAMHHNPRYWPEPERFDPERFSPEQERARHKYAYIPFGAGSRVCIGNVFAMMEAQLL 408

Query: 511 LSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           L+T+++++    D  +   +    I L    G +VRL  R+
Sbjct: 409 LATMMQHYDFTLDPTQR-VEYDPQITLGVKHGLRVRLAQRQ 448



 Score = 48.8 bits (111), Expect = 4e-04
 Identities = 30/128 (23%), Positives = 64/128 (50%), Gaps = 3/128 (2%)

Query: 93  IGPRLLVFLYDPRDV-EVILSSHVYIDK-AEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 150
           +GP  +  + DP  + E+++++   + K   +      +LGNGLL + G   +  RKL+ 
Sbjct: 44  MGPFRVYLVNDPAGIQELLVTNRDKVRKNGGDRELLSRFLGNGLLSNDGADHQKQRKLVQ 103

Query: 151 PTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVSKSTQD 210
           P FH+  ++++ +    +++A++++   + +  D    M E T+ I+ +T      S Q+
Sbjct: 104 PAFHMKRIQAYAETMVEHTQAMLERW-HDGAILDMDQAMMELTLTIVTKTLFNADISEQE 162

Query: 211 QSGFEYAM 218
                 AM
Sbjct: 163 VRQVSQAM 170


>UniRef50_UPI00015B5352 Cluster: PREDICTED: similar to cytochrome
           P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 507

 Score =  135 bits (327), Expect = 3e-30
 Identities = 71/239 (29%), Positives = 130/239 (54%), Gaps = 11/239 (4%)

Query: 325 RLAFLDLLLESSQS--GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           R   + LL+++ +   G+ ++ ++I  Q       G ++T++   F L  +  + DIQD+
Sbjct: 269 RQDMMQLLIQAMKKDDGIKVTMDDIIGQAFFFFLAGFESTSSAMCFALQELAANPDIQDR 328

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           + +E+D         +T++  + +KYL+  + ETLR YPPV I  R  N+E T P   + 
Sbjct: 329 LRQEIDDEIEQHGGELTYESLVNLKYLDMVMSETLRKYPPVAITNRLCNKEYTFPPLMEG 388

Query: 443 IP-----AGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 497
            P      GT+++I+ + LHR P  +P+P KFDP+ F  E     + Y ++PF  GPR C
Sbjct: 389 YPEYQMEVGTSILISMFGLHRDPKYFPDPEKFDPERFNDENKHKINPYTYMPFGIGPRQC 448

Query: 498 VGRKYAMLKLKVILSTILRNFRVISDLKESDFKL---QADIILKRAEGFQVRLQPRKRM 553
           +  ++A+++ K+++  ILR F V+   ++S   +   +   IL   EG+  + + RK++
Sbjct: 449 IANRFALMEAKIVIIDILRKF-VVKFTEKSHHPVTLSKKTFILSAEEGYWFKFEGRKKV 506



 Score = 36.3 bits (80), Expect = 2.1
 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 7/132 (5%)

Query: 128 PWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKL---KKEASNFD 184
           P +G  +    GQ+W+  R  + P++    +K    L    S+  V       + A NF+
Sbjct: 116 PIVGRNIFSLRGQRWKEVRNTLTPSYTAARIKMLFALVAECSKDFVQYFVDHPELAENFE 175

Query: 185 CHDYMSECTVEILLETAMGV---SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLL 241
             D ++  T +++   A GV   S   QD   + +   V     +  L+ T +   P+++
Sbjct: 176 AKDAITRYTNDVVASAAFGVKVDSMKDQDNEFYLHGKEVTNFSALAALKFTILKNFPNIM 235

Query: 242 -FKFTDYAKNQT 252
            F  T +  N T
Sbjct: 236 KFFGTTFLPNAT 247


>UniRef50_Q98T91 Cluster: Cytochrome P450 3A40; n=16;
           Euteleostomi|Rep: Cytochrome P450 3A40 - Oryzias latipes
           (Medaka fish) (Japanese ricefish)
          Length = 502

 Score =  135 bits (327), Expect = 3e-30
 Identities = 75/237 (31%), Positives = 133/237 (56%), Gaps = 12/237 (5%)

Query: 322 QKKRLAFLDLLLES---SQSGV---AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGI 375
           QK R+ FL L+++S   +Q+G+    +SD EI  Q    +F G++TT++  +F    +  
Sbjct: 265 QKSRIDFLQLMIDSQKNNQNGLQDKGLSDHEILSQAMIFIFAGYETTSSSLTFLAYNLAT 324

Query: 376 HQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEIT 435
           + ++  K+ +E+D  F +   PV +   +EM+YL+  + E+LRLYP    + R    + T
Sbjct: 325 NPEVMKKLQKEIDATFPNK-APVQYVPLMEMEYLDCVVNESLRLYPIAARLERVA--KAT 381

Query: 436 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495
           +  NG  IP    +++ T+ LHR P+++P P KF P+ F  E       Y ++PF AGPR
Sbjct: 382 VEVNGLVIPKDMVVMVPTWPLHRDPELWPEPEKFKPERFSKENKDTFDPYTYMPFGAGPR 441

Query: 496 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI--ILKRAEGFQVRLQPR 550
           +C+G ++A++ +K+ +  IL+ +   S  KE++   + D+   L      Q++L PR
Sbjct: 442 NCIGMRFALVMMKLAVVEILQTYD-FSVCKETEVPFEMDVQGFLAPKRPIQLKLTPR 497



 Score = 41.9 bits (94), Expect = 0.043
 Identities = 26/138 (18%), Positives = 61/138 (44%), Gaps = 6/138 (4%)

Query: 91  IWIGPRLLVFLYDPRDVEVILSSHVY--IDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148
           I+ G + ++ + DP  ++ +L    Y        +R   P L + + I+   +W+  R +
Sbjct: 74  IYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFRLNGP-LYDAVSIAEDDQWKRIRSV 132

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 205
           ++P+F    LK   D+   +S  ++  +KK+       +  +Y    +++++  TA  V 
Sbjct: 133 LSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEMKEYFGPYSMDVVTSTAFSVD 192

Query: 206 KSTQDQSGFEYAMAVMKM 223
             + +     +   + KM
Sbjct: 193 IDSLNNPSDPFVTNIKKM 210


>UniRef50_Q9PWP0 Cluster: Cytochrome P450; n=2; Dicentrarchus
           labrax|Rep: Cytochrome P450 - Dicentrarchus labrax
           (European sea bass)
          Length = 526

 Score =  135 bits (326), Expect = 3e-30
 Identities = 63/184 (34%), Positives = 110/184 (59%), Gaps = 3/184 (1%)

Query: 323 KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           +K+  F+D++L S  + G  ++DEEI+ + +T MF GHDTTA+   + L  +  H   Q+
Sbjct: 292 QKKKDFVDIILLSRDEDGQGLTDEEIQAEANTFMFAGHDTTASAICWTLYNLARHDQYQE 351

Query: 382 KVIEELDQIFGDSDR-PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
           K  +E+ ++    DR  + ++D   + +   C+ E+LRL+ PV  + R+  Q++TLP + 
Sbjct: 352 KCRQEVMELMEGRDRHEIEWEDLSNLPFTTMCIRESLRLHSPVQAVTRKYTQDMTLPGDC 411

Query: 441 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
             +P G   +++ Y  H  P V+ NP++F P  F P        +AF+PFS+GPR+C+G+
Sbjct: 412 T-VPKGAICLVSIYGTHHNPTVWTNPHEFHPLRFDPTNKEGLAAHAFIPFSSGPRNCIGQ 470

Query: 501 KYAM 504
           K+A+
Sbjct: 471 KFAL 474



 Score =  101 bits (242), Expect = 5e-20
 Identities = 56/186 (30%), Positives = 105/186 (56%), Gaps = 8/186 (4%)

Query: 92  WIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 148
           ++GP   LV L+ P  V+ +L +   I   +E  Y   +PWLG  LL+S G++W   R+L
Sbjct: 93  FLGPFYHLVRLFHPDYVKPLLMAPASITVKDELIYGHLRPWLGQSLLLSNGEEWSRKRRL 152

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDK----LKKEASNFDCHDYMSECTVEILLETAMGV 204
           + P FH ++L++++ +FN ++  + DK    L    +N +  D+++  T++ LL+ A   
Sbjct: 153 LTPAFHFDILRNYVAIFNTSTNTMHDKWRHHLAVGTTNLEMFDHITLMTLDSLLKCAFSY 212

Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264
           + + Q QS  EY  A++++ D++  R  KI    D ++  T   K   K L I+H  T++
Sbjct: 213 NSNCQ-QSTSEYVSAIVELSDLIIDRRQKILHHWDWIYWKTKQGKRFKKALSIVHRFTRE 271

Query: 265 VIKRKK 270
           V+++++
Sbjct: 272 VVQKRR 277


>UniRef50_Q8WQN9 Cluster: Cytochrome P450 CYP4J5; n=22;
           Endopterygota|Rep: Cytochrome P450 CYP4J5 - Anopheles
           gambiae (African malaria mosquito)
          Length = 153

 Score =  134 bits (325), Expect = 4e-30
 Identities = 66/154 (42%), Positives = 96/154 (62%), Gaps = 4/154 (2%)

Query: 350 QVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRP---VTFQDTLEM 406
           +VDT MFEGHDTT +   F L  +    +IQ ++ +EL Q+   +D     ++  D    
Sbjct: 1   EVDTFMFEGHDTTGSALVFILLTLSWELEIQTRLHQELSQLATQNDLTDGHLSPNDLNSA 60

Query: 407 KYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNP 466
           K+ +R + E LRL+PPV  I+R V +EI LP +G+ IP G    +  + LHR P  +P+P
Sbjct: 61  KFFDRVIKECLRLWPPVAFISRSVTEEIHLP-DGRIIPQGCIANLHIFDLHRDPAQFPDP 119

Query: 467 NKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 500
            +FDPD FLPE  + R  YA++PFSAGPR+C+G+
Sbjct: 120 ERFDPDRFLPECVSQRSPYAYIPFSAGPRNCIGQ 153


>UniRef50_UPI0000E4963D Cluster: PREDICTED: similar to cytochrome
           P450 3A69; n=7; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to cytochrome P450 3A69 -
           Strongylocentrotus purpuratus
          Length = 508

 Score =  134 bits (324), Expect = 6e-30
 Identities = 95/386 (24%), Positives = 168/386 (43%), Gaps = 17/386 (4%)

Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEI 196
           Q W+  R +I PTF    +K    L N +S  +V     ++++  N          T++ 
Sbjct: 75  QHWKDVRNVITPTFSAVKMKQLSGLLNESSDTLVKNFGAIQEKEGNVKVFSLFEAFTMDG 134

Query: 197 LLETAMGVSKSTQDQSG---FEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTK 253
           + + A G+   +Q+        +A  +MK    L      I+ R   +  + + +    +
Sbjct: 135 IAKCAFGIQVDSQNDPSDPFVTHAKDLMKNRFALKFVIAGIFPRIGKIMDYFEVSTLPPE 194

Query: 254 LLDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQSSGLKXX 313
           +      +  + I  +KE   S K    L      ++ +  +   +E     +    K  
Sbjct: 195 VSSFFISVVDQAIAARKESGGS-KMKDFLQLMLNAAQENKSEKEMIEE----KPQDEKVE 249

Query: 314 XXXXXXXGQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMM 373
                    +   ++ DL          ++ +EI  Q       G+DT      F    +
Sbjct: 250 GDLYALIEDQDNKSYFDL---KKSKKTTLTKDEIYGQAMLFFLAGYDTINTTLGFLTYSL 306

Query: 374 GIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQE 433
             + ++QDK+IEE+D      D  V +    +M YL+  + E LRLYP   II RQ N+ 
Sbjct: 307 ATNPEVQDKLIEEIDNETPARD-DVGYNSVAKMSYLDNVVCEILRLYPAGLIIERQCNE- 364

Query: 434 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAG 493
            T   NG  IP  + +    Y +HR P ++P+P KFDP+ F  E    RH  A++PF AG
Sbjct: 365 -THVCNGLTIPKDSQIFFPVYAIHRDPAIWPDPEKFDPERFTKENREGRHPLAWMPFGAG 423

Query: 494 PRSCVGRKYAMLKLKVILSTILRNFR 519
           PR+C+G ++A++++K+    +L+ +R
Sbjct: 424 PRNCIGMRFALMEIKMATVRLLQKYR 449


>UniRef50_UPI0000E48EAF Cluster: PREDICTED: similar to cytochrome
           P450 CYP3A24; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to cytochrome P450 CYP3A24 -
           Strongylocentrotus purpuratus
          Length = 412

 Score =  134 bits (324), Expect = 6e-30
 Identities = 59/189 (31%), Positives = 108/189 (57%), Gaps = 3/189 (1%)

Query: 332 LLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIF 391
           L + S S + +++ E+  Q       G++TT     + L ++  H D+QDK++ E+D + 
Sbjct: 195 LQKKSSSKIRLNESEVISQALIFFLAGYETTNTTCGYMLYLLATHPDVQDKLVNEIDDVA 254

Query: 392 GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVI 451
            +++  V +Q   +M YLE+   ET R+YPP  +  R  N+   +  NG  +P G  + I
Sbjct: 255 PEAE-DVGYQSISKMPYLEQIFCETERIYPPALMTDRVCNEPFDI--NGFTVPKGMRIFI 311

Query: 452 ATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVIL 511
             + +H  P+++P+P  +DPD F  E     H  A++PF  GPR+CVG ++AM++ K+++
Sbjct: 312 PIFTIHHDPNLWPDPETYDPDRFSKENREKHHPCAWMPFGTGPRNCVGMRFAMMEAKMVI 371

Query: 512 STILRNFRV 520
             IL+ +++
Sbjct: 372 VRILQKYQI 380


>UniRef50_UPI000065CBAF Cluster: Thromboxane-A synthase (EC
           5.3.99.5) (TXA synthase) (TXS) (Cytochrome P450 5A1).;
           n=1; Takifugu rubripes|Rep: Thromboxane-A synthase (EC
           5.3.99.5) (TXA synthase) (TXS) (Cytochrome P450 5A1). -
           Takifugu rubripes
          Length = 391

 Score =  134 bits (323), Expect = 8e-30
 Identities = 63/181 (34%), Positives = 110/181 (60%), Gaps = 3/181 (1%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           I+++EI  Q    +  G++T++   +F   ++ I+ + Q ++ +E+D  F   + P  + 
Sbjct: 205 ITEDEIVGQAFVFLVAGYETSSNTLAFACYLLAINPECQRELQKEVDHFFTRHESP-DYT 263

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
           +  E+KYL+  + ETLRLYPP    AR++ ++  +  NG+  P G T  I    LHR P+
Sbjct: 264 NVQELKYLDMVISETLRLYPPGFRFAREIERDCVV--NGQSFPKGATFEIPAGFLHRDPE 321

Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVI 521
            +P+P+KF P+ F PE  A+RH + ++PF AGPR+CVG + A L++K+ L  + R F ++
Sbjct: 322 HWPDPDKFIPERFTPEAKASRHPFVYIPFGAGPRNCVGMRLAQLEMKMALVRLFRRFNLL 381

Query: 522 S 522
           +
Sbjct: 382 A 382



 Score = 40.3 bits (90), Expect = 0.13
 Identities = 20/90 (22%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 124 RFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV---DKLKKEA 180
           RF    + + LL+   ++W+  R ++ P F  + +K  + L N  + A++   D   + A
Sbjct: 37  RFITKPMSDCLLMLRNERWKRVRSILTPAFSASKMKEMVPLINTATDALIKNLDAFAESA 96

Query: 181 SNFDCHDYMSECTVEILLETAMGVSKSTQD 210
             F+ H      T++++   A G    +Q+
Sbjct: 97  EAFNIHKCFGCFTMDVVASVAFGTQVDSQN 126


>UniRef50_Q1D9Z9 Cluster: Cytochrome P450 family protein; n=1;
           Myxococcus xanthus DK 1622|Rep: Cytochrome P450 family
           protein - Myxococcus xanthus (strain DK 1622)
          Length = 458

 Score =  134 bits (323), Expect = 8e-30
 Identities = 65/194 (33%), Positives = 117/194 (60%), Gaps = 6/194 (3%)

Query: 329 LDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           L +++E+    +G  +SD +++++V T++  GH+TTA+  ++ + ++  H  ++  +  E
Sbjct: 240 LQMMMEAHDDDTGERMSDSQLRDEVLTLLLAGHETTASALAWTIMLLSQHPGVRRDMESE 299

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           L +  G   R  T +D   ++   R + E+LRLYPP   ++R   +E  +   G +IP G
Sbjct: 300 LARELG--GRNPTHEDLPRLELTHRVVDESLRLYPPAWALSRIATKEDLV--GGFRIPKG 355

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
             L+IA +  HR P ++ NP  FDPD FLPER   R  +A+ PF  GPR C+G ++A+++
Sbjct: 356 AHLLIAPWVTHRHPSIWDNPEGFDPDRFLPEREQARPRFAWFPFGGGPRQCIGNQFALME 415

Query: 507 LKVILSTILRNFRV 520
           L ++L+T+L+  R+
Sbjct: 416 LVLVLATLLQRVRL 429



 Score = 52.4 bits (120), Expect = 3e-05
 Identities = 37/134 (27%), Positives = 60/134 (44%), Gaps = 7/134 (5%)

Query: 84  DHESVVKIWIGPRLLVFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLGNGLLISTGQK 141
           ++  VV++ +GP  LV +  P  V  +L  H   Y  ++  +R  +  LG+GLL S G  
Sbjct: 44  EYGDVVRLPMGPADLVLVAHPDGVRHVLQDHARNYSKQSRGFRVLQELLGHGLLTSDGDH 103

Query: 142 WRSHRKLIAPTFHLNVLKSFIDLF---NANSRAVVDKLKKEASNFDCHDYMSECTVEILL 198
           W   R+L  P FH   +  F        A+  A ++      + F+  +  +  T+ I  
Sbjct: 104 WLRQRRLAQPAFHRQRVAGFTRTMVDAAADLAATMEARADTGAAFNVAEDFTRLTLRIAS 163

Query: 199 ETAMG--VSKSTQD 210
            T  G  VS +T D
Sbjct: 164 STLFGADVSSATHD 177


>UniRef50_Q5TXA2 Cluster: ENSANGP00000026709; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000026709 - Anopheles gambiae
           str. PEST
          Length = 198

 Score =  134 bits (323), Expect = 8e-30
 Identities = 64/198 (32%), Positives = 118/198 (59%), Gaps = 5/198 (2%)

Query: 326 LAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIE 385
           + FLD LL + + G  +  +EI+  + TI+  G +TTA   +F L M+ +H ++QD+V E
Sbjct: 1   MVFLDQLLHTQRGGRDLEMQEIENHLYTIIGAGSETTANQVAFILLMIAMHPEVQDRVHE 60

Query: 386 ELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445
           E+  I+G +    +++      YLE+ + ET+R+YP  P+I R+  + + L      +P+
Sbjct: 61  EIVSIYGRAAPDFSYETISAQTYLEQVIKETMRVYPVAPLIGRETIETVKL--GDVIVPS 118

Query: 446 GTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPE--RSANRHYYAFVPFSAGPRSCVGRKY 502
           G TL+I    LHR  +++    + FDPD F P    +  +H ++++PF  GPR+C+G +Y
Sbjct: 119 GVTLLINILTLHRNKELWGERAHVFDPDRFDPALYDAKKQHPFSYIPFGGGPRNCIGYRY 178

Query: 503 AMLKLKVILSTILRNFRV 520
            M  +K++++ +LR +++
Sbjct: 179 GMFAMKIMVTQVLRKYQL 196


>UniRef50_Q495Y1 Cluster: CYP3A43 protein; n=4; Homo sapiens|Rep:
           CYP3A43 protein - Homo sapiens (Human)
          Length = 393

 Score =  134 bits (323), Expect = 8e-30
 Identities = 71/218 (32%), Positives = 120/218 (55%), Gaps = 9/218 (4%)

Query: 322 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 376
           QK R+ F   +++S     ++S  A+SD E+  Q   I+F  +DTT+    F +  +  H
Sbjct: 155 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 214

Query: 377 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 436
            D+Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +
Sbjct: 215 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 273

Query: 437 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496
             NG  IP G  +++  Y LH  P  +  P KF P+ F  +   +   Y ++PF AGPR+
Sbjct: 274 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 331

Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 534
           C+G ++A+  +K+ +   L+NF      KE+   L+ D
Sbjct: 332 CIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 368


>UniRef50_Q0IEL1 Cluster: Cytochrome P450; n=6; Culicini|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 511

 Score =  133 bits (322), Expect = 1e-29
 Identities = 73/214 (34%), Positives = 118/214 (55%), Gaps = 8/214 (3%)

Query: 341 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 400
           ++S +E+  QV      G++T+++  SF L  +  HQDIQ KV +E+D +  + +  +T+
Sbjct: 297 SLSIDEVTAQVMVFFVAGYETSSSTVSFCLFELARHQDIQAKVHQEIDTVLAEHEGNLTY 356

Query: 401 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 460
                MKYLE+CL ET+R YPPV I+ R+  +   +P     +  GT +V+    +HR P
Sbjct: 357 ASLASMKYLEQCLEETVRKYPPVAILNRECTKTYRIPETDVIVEKGTPIVVPLMGMHRDP 416

Query: 461 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520
             +P PN F PD F  E  A     A+  F AGPR C+G +  +L+ KV + T+LR F+ 
Sbjct: 417 QYFPQPNDFQPDRF--EGGAQSK--AYFGFGAGPRLCIGMRLGILQSKVAVVTLLRKFKF 472

Query: 521 -ISDLKESDFKLQ---ADIILKRAEGFQVRLQPR 550
            +++ ++   +L+      IL    G Q+ +Q R
Sbjct: 473 SLANPEDQHTELRMKPRSFILTTEGGIQLVVQQR 506


>UniRef50_A7DM29 Cluster: Cytochrome P450; n=2; Methylobacterium
           extorquens PA1|Rep: Cytochrome P450 - Methylobacterium
           extorquens PA1
          Length = 471

 Score =  133 bits (321), Expect = 1e-29
 Identities = 72/224 (32%), Positives = 125/224 (55%), Gaps = 9/224 (4%)

Query: 329 LDLLLESS--QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           L LLL++   ++G  +SDE + + + T +  GH+TTA    + L ++  H  ++ ++++E
Sbjct: 252 LGLLLQAKDPETGERLSDESLIDNLLTFVAAGHETTALALIWTLRVLADHPAVEARILDE 311

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           +  + G    P        + +  + ++E +RLYPP P+I R+  +E+ L      IPAG
Sbjct: 312 IAGL-GADPAPEALD---RLAFTRQVVLEVMRLYPPAPLIVRRTAEEVRL--GDMVIPAG 365

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
            ++ +  Y LHR   ++  P+ FDPD F PE +A+R  YA++PF AGPR C+G   A+ +
Sbjct: 366 ESVHVPVYALHRHQSLWERPDVFDPDRFAPELTASRDRYAYLPFGAGPRVCIGMGLALTE 425

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
             VIL+T+L  FR +    E     Q  + L+   G ++++ PR
Sbjct: 426 CLVILATLLPAFRFVPAKAEMP-ATQFRVTLRPKGGMKMKVVPR 468



 Score = 37.5 bits (83), Expect = 0.92
 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 70  ADIFRNIVQKSAD--YDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEY--RF 125
           A + R++++   D  Y    V   ++G R   ++  P  +  ++       + E +  R 
Sbjct: 32  ATMLRSLIEAWPDEVYTRPLVTTRFLGQRT-TYVCAPGHIRSLIVDQAGALEREPFMLRA 90

Query: 126 FKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFI 162
             P LG+G+L + G  WR  R+  AP F  + +K+FI
Sbjct: 91  LAPALGSGILTADGPHWRGQRRTAAPMFRPDRVKAFI 127


>UniRef50_Q9PVE8 Cluster: Cytochrome P450 3A30; n=4;
           Percomorpha|Rep: Cytochrome P450 3A30 - Fundulus
           heteroclitus (Killifish) (Mummichog)
          Length = 496

 Score =  133 bits (321), Expect = 1e-29
 Identities = 72/236 (30%), Positives = 132/236 (55%), Gaps = 11/236 (4%)

Query: 322 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 376
           QK R+ FL L+++S     +Q   +++D EI  Q    +F G++T+++  +F    +  +
Sbjct: 264 QKSRVDFLQLMIDSQKNSGAQQDKSLTDHEILSQSMIFIFAGYETSSSSLTFLAYNLATN 323

Query: 377 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 436
            ++  K+ EE+D  F +   PV +Q  +EM+YL+  + E+LRL+P    + R     + +
Sbjct: 324 PEVMKKLQEEIDATFPNK-APVHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAAVEI 382

Query: 437 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 496
             NG  IP    ++I T+ LHR P+++P P  F P+ F  +   N   Y ++PF +GPR+
Sbjct: 383 --NGVVIPKDMVVMIPTWPLHRDPEIWPEPEAFKPERFSKKNKDNIDPYIYMPFGSGPRN 440

Query: 497 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI--ILKRAEGFQVRLQPR 550
           C+G ++A++ +K+ +  IL+ +   S  KE++   + DI  +L      Q++L PR
Sbjct: 441 CIGMRFALVLIKLAVVEILQQYS-FSVCKETEVPFEMDIQGLLAPKRPIQLKLVPR 495



 Score = 39.1 bits (87), Expect = 0.30
 Identities = 25/138 (18%), Positives = 62/138 (44%), Gaps = 6/138 (4%)

Query: 91  IWIGPRLLVFLYDPRDVEVILSSHV--YIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKL 148
           I+ G + ++ + DP  ++ +L      +      +R   P L + + I+   +W+  R +
Sbjct: 73  IYDGRQPVLCVTDPEIIKAVLVKECLSFFTNRRNFRLNGP-LYDAVSIAEDDQWKRIRSV 131

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 205
           ++P+F    LK   ++   +S  ++  +KK+A      D  ++    +++++  TA  V 
Sbjct: 132 LSPSFTSGRLKEMFEIMKNHSANLIRSMKKKADKDEPLDLKEFFGSYSMDVVTSTAFSVD 191

Query: 206 KSTQDQSGFEYAMAVMKM 223
             + +     +   + KM
Sbjct: 192 IDSLNNPSDPFVTNIKKM 209


>UniRef50_O76345 Cluster: Cytochrome P450; n=1; Homarus
           americanus|Rep: Cytochrome P450 - Homarus americanus
           (American lobster)
          Length = 518

 Score =  132 bits (320), Expect = 2e-29
 Identities = 59/198 (29%), Positives = 120/198 (60%), Gaps = 9/198 (4%)

Query: 329 LDLLLESSQSGV-----AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383
           L LL++++ + V      ++DEE+ +     +  G +TT+   ++   ++ ++ DIQ+K+
Sbjct: 266 LQLLVDAADANVDASKTKLTDEEVVDNAFLFLLAGFETTSTALTYTSYLLALNPDIQEKI 325

Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQEITLPSNGKK 442
            +E++++ G  +R  +++D  ++ Y E   +E+ R+YPPV   I RQ  Q+         
Sbjct: 326 FQEVEEVVG-LERAPSYEDLSKLVYTEAVALESTRMYPPVTGFITRQATQDWQY--GPYT 382

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           IPAGT + +  + +H  P++YP P  F P+ FLP+   +RH  A++ F  GPR+C+G ++
Sbjct: 383 IPAGTEVEVPVWSIHHNPELYPQPELFKPERFLPKAKKDRHTMAYLGFGGGPRNCLGLRF 442

Query: 503 AMLKLKVILSTILRNFRV 520
           A++++K++LS++++ F +
Sbjct: 443 ALMEMKLVLSSVIQRFYI 460


>UniRef50_Q70AR5 Cluster: Putative cytochrome P450; n=1;
           Streptomyces peucetius|Rep: Putative cytochrome P450 -
           Streptomyces peucetius
          Length = 477

 Score =  132 bits (319), Expect = 2e-29
 Identities = 60/184 (32%), Positives = 108/184 (58%), Gaps = 4/184 (2%)

Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396
           +SG   +DE+I+++V      GH+T +   S+   ++ ++ + + ++  E+D++   + R
Sbjct: 265 ESGGMFTDEQIRDEVSGFFVAGHETVSTALSWTWYLLSLNPESRRRLQAEVDEVL--AGR 322

Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456
             T  D  ++ Y    L E++RLYPP+ +  R   ++  +   G  IP G  +V+  Y  
Sbjct: 323 VPTVDDLPKLTYTTMVLQESMRLYPPIFVYMRCAAEDDVI--GGYHIPEGRWVVVCPYVT 380

Query: 457 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 516
           HR P+ + NP  F+P+ F PE SANRH  A++PF AGPR C+G  +AML++ ++++ I +
Sbjct: 381 HRHPEFWDNPEGFEPERFTPENSANRHRMAYLPFGAGPRKCIGDSFAMLQMPLVVAMIAQ 440

Query: 517 NFRV 520
            FR+
Sbjct: 441 RFRL 444



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 34/144 (23%), Positives = 64/144 (44%), Gaps = 5/144 (3%)

Query: 130 LGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYM 189
           +G+GL+ + G  W   R+L  P FH ++L+ F D F A++  ++D  ++ A + +  D  
Sbjct: 109 VGDGLVAAEGTSWLRSRRLTQPAFHRDILRRFGDSFTASTAELLDGWERRARDGEPLDIK 168

Query: 190 SECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAK 249
           SE     L   A  + ++           AV +     H R T     P    KF   A+
Sbjct: 169 SEMMHLSLANLARALFRTEWTDEVSRIEPAVQEALGFTHRRMTS----PVDPLKFPSAAR 224

Query: 250 NQTK-LLDIIHGLTKKVIKRKKEE 272
            + +  L+ I+ L   ++  ++ +
Sbjct: 225 TRFRGALETINSLLYPMVAERRRD 248


>UniRef50_Q9VGB5 Cluster: Probable cytochrome P450 313a5; n=2;
           Drosophila melanogaster|Rep: Probable cytochrome P450
           313a5 - Drosophila melanogaster (Fruit fly)
          Length = 487

 Score =  132 bits (319), Expect = 2e-29
 Identities = 74/217 (34%), Positives = 120/217 (55%), Gaps = 4/217 (1%)

Query: 327 AFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           A +D +L   + G  +S +++  +   I+F   DT +   +  L +M +    QD V EE
Sbjct: 263 ALIDRILNLVRIG-ELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEE 321

Query: 387 LDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445
           L ++F    +   +  D  ++  L+R L ET+RL P VP++ RQ +  I L SNG  IP 
Sbjct: 322 LAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQL-SNGFYIPE 380

Query: 446 GTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAM 504
           G TL+I  +  HR  D++ P  N F+PDNFLPE    R  Y+++PFS G ++C+G K ++
Sbjct: 381 GVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSL 440

Query: 505 LKLKVILSTILRNFRVISDLKESDFKLQADIILKRAE 541
           +  K+ L+ ILRN+ + +     D +   +  +K AE
Sbjct: 441 ISAKLALAKILRNYMLSTTFLYKDLRFIDNTTMKLAE 477



 Score = 54.8 bits (126), Expect = 6e-06
 Identities = 57/257 (22%), Positives = 106/257 (41%), Gaps = 11/257 (4%)

Query: 30  ILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADI-FRNIVQKSADYDHESV 88
           I+   Y+  SRRR Y +  KL           A E++     I  R I+ K     +   
Sbjct: 12  IILCVYFLWSRRRFYIMMLKLPGPMGFPFIGLAFEYIRLKRKIRLRTILFKI----YGKT 67

Query: 89  VKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEY-RFFKPWLGNGLLISTGQKWRSHRK 147
           V  WIG   ++   +P+ +E I +S    +++    +     LG GLL      W   RK
Sbjct: 68  VLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRK 127

Query: 148 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK--EASNFDCHDYMSECTVEILLETAMG-- 203
           L+ P+F  N + SF+ + N  +  +V  L +  +  + +    +++ + +I  +  MG  
Sbjct: 128 LLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWSFKIAAQITMGDE 187

Query: 204 VSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTK 263
           V      Q+G     +   + +++ +     WLR   L K   Y K + +     +   K
Sbjct: 188 VRNQANYQNG-NLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNAFIK 246

Query: 264 KVIKRKKEEFASGKKPS 280
            +I +K     +  +P+
Sbjct: 247 DIIDKKLSSTDNSSEPA 263


>UniRef50_Q309A5 Cluster: Cytochrome P450 monooxygenase; n=22;
           Apocrita|Rep: Cytochrome P450 monooxygenase - Apis
           mellifera (Honeybee)
          Length = 499

 Score =  132 bits (318), Expect = 3e-29
 Identities = 64/198 (32%), Positives = 112/198 (56%), Gaps = 5/198 (2%)

Query: 328 FLDLLLESSQS-----GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           F+++L+E  ++      + ++D  I  Q       G +T++   S  L  + ++QD+Q K
Sbjct: 270 FINMLMELQKNPQKLENIKLTDSLIAAQAFVFFLAGFETSSTTMSNALYELALNQDVQKK 329

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           + EE++     +++ + + D  EM+YL++   ETLR+YPP  I+ R+   + T       
Sbjct: 330 LREEINTFCPKNNKELKYDDIKEMEYLDKVFKETLRMYPPASILMRKAISDYTFNDTKIT 389

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           IP    + I  + +HR   +YPNP+ FDP+ F  +  A+RH   ++PF  GPR+C+G ++
Sbjct: 390 IPKEMKIWIPAFAIHRDSAIYPNPDSFDPERFDQDAMASRHPMHYLPFGDGPRNCIGARF 449

Query: 503 AMLKLKVILSTILRNFRV 520
           A+ + KV L TILRN +V
Sbjct: 450 AVYQTKVGLITILRNHKV 467



 Score = 34.7 bits (76), Expect = 6.5
 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 140 QKWRSHRKLIAPTFHLNVLKSFIDLF---NANSRAVVDKLKKEASNFDCHDYMSECTVEI 196
           ++WR  R  ++P F    LK    L    + N    +DKL ++    +C +  +  T ++
Sbjct: 126 ERWRPLRSRLSPIFTSGKLKEMFYLIIECSLNLETYLDKLIEKNEPIECRELTARFTTDV 185

Query: 197 LLETAMGVSKSTQDQSGFEY 216
           +   A G+  S+      E+
Sbjct: 186 IGSCAFGIDMSSMTNENSEF 205


>UniRef50_P33270 Cluster: Cytochrome P450 6a2; n=10; Diptera|Rep:
           Cytochrome P450 6a2 - Drosophila melanogaster (Fruit
           fly)
          Length = 506

 Score =  132 bits (318), Expect = 3e-29
 Identities = 76/238 (31%), Positives = 127/238 (53%), Gaps = 13/238 (5%)

Query: 324 KRLAFLDLLLESSQSG-VAISDEEIKE---------QVDTIMFEGHDTTAAGSSFFLSMM 373
           KR  F++LL+E  Q G V + + E+ E         QV      G +T+++  S+ L  +
Sbjct: 267 KRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYEL 326

Query: 374 GIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQE 433
             +QDIQD++  E+  +  + +  +T++    M YL + + ETLRLY  VP + R+   +
Sbjct: 327 AQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALND 386

Query: 434 ITLPSNGKK-IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 492
             +P + K  I  GT ++I     HR  D+YPNP  FDP+ F PE+ A R    ++PF  
Sbjct: 387 YVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGD 446

Query: 493 GPRSCVGRKYAMLKLKVILSTILRNFRV-ISDLKESDFKLQ-ADIILKRAEGFQVRLQ 548
           GPR+C+G ++  ++ ++ L+ I+  FRV + D  E   K     I+L    G  +R++
Sbjct: 447 GPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVE 504


>UniRef50_Q9VYQ7 Cluster: Probable cytochrome P450 311a1; n=2;
           Drosophila melanogaster|Rep: Probable cytochrome P450
           311a1 - Drosophila melanogaster (Fruit fly)
          Length = 483

 Score =  132 bits (318), Expect = 3e-29
 Identities = 74/219 (33%), Positives = 121/219 (55%), Gaps = 7/219 (3%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           LD LL +   G ++S  EI+++++T +F G DTT A  SF L  +    + Q ++ +EL 
Sbjct: 265 LDTLLLAKFEGQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQ 324

Query: 389 QIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447
            +  D     T  D L  + YLE  + E LRLY  VP   RQ  Q   +   G+   AG 
Sbjct: 325 DVALDE---TTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEI--GGRTYCAGV 379

Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGPRSCVGRKYAMLK 506
           TL I  Y L    + YP+P  F P+ +LPE  A     ++++PFS GP  C+GR+Y++L 
Sbjct: 380 TLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLL 439

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQV 545
           +K++ + ++R F++    +++  +L+A ++LK  +G  V
Sbjct: 440 MKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINV 478



 Score = 81.4 bits (192), Expect = 6e-14
 Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 2/192 (1%)

Query: 90  KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLI 149
           ++ +GP+L VFL+   +    L     + KA+ +   +P +GNGLLIS G  W   R+L+
Sbjct: 68  RLRLGPQLWVFLHSAEETRQALHDPT-LRKADTFMQLEPLIGNGLLISHGAHWTRQRRLL 126

Query: 150 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASNF-DCHDYMSECTVEILLETAMGVSKST 208
            P F   +L+SF      +   +V +L      F +  + +  C ++ +++T+MG    T
Sbjct: 127 TPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSMGAQLDT 186

Query: 209 QDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKR 268
           Q         A      +L  R     L  D +F+ T   ++  + L +IH   + VI++
Sbjct: 187 QSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEK 246

Query: 269 KKEEFASGKKPS 280
           + +E     +P+
Sbjct: 247 RAKELLDMGEPA 258


>UniRef50_UPI00015B480C Cluster: PREDICTED: similar to cytochrome
           P450 monooxygenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to cytochrome P450 monooxygenase -
           Nasonia vitripennis
          Length = 730

 Score =  131 bits (317), Expect = 4e-29
 Identities = 63/197 (31%), Positives = 111/197 (56%), Gaps = 5/197 (2%)

Query: 329 LDLLLESSQSGVAISDEEIKE-----QVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKV 383
           +D+L++  ++    +DEEI E     Q       G DTT+   S  +  + ++ DIQ+K+
Sbjct: 502 VDVLMDIKENPEQFNDEEITELFLTAQAFVFFIAGFDTTSNAMSHAMYELALNPDIQEKL 561

Query: 384 IEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443
            +E++  + +++   ++     MKYL++   ETLR YPP   ++R+     +       I
Sbjct: 562 RQEVNATYSENNGKFSYDSVRNMKYLDKVFKETLRKYPPAFTLSRKSMNNHSFSGTKITI 621

Query: 444 PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYA 503
           P GT+L+I TY +H  P  YP+P+KFDP+ F    + NR +  F+PF  GPR+C+G ++A
Sbjct: 622 PKGTSLMIPTYAIHHDPSYYPDPDKFDPERFDEGNANNRIHMTFLPFGDGPRNCIGERFA 681

Query: 504 MLKLKVILSTILRNFRV 520
             + KV ++  +R F++
Sbjct: 682 NNQFKVGIAMTVRKFKL 698


>UniRef50_A7RQ80 Cluster: Predicted protein; n=5; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 459

 Score =  131 bits (317), Expect = 4e-29
 Identities = 58/190 (30%), Positives = 116/190 (61%), Gaps = 3/190 (1%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           L+ +++       +++ EI  Q    M  G++ T +  +F    +  + DIQ+K+ +E+D
Sbjct: 239 LEAMIDDETKKKRMTEAEIIAQCLIFMIAGYEGTNSALTFICYNLATNPDIQEKLQQEID 298

Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448
            ++ D+D+ +++    E+ YL+  + ETLR+YPP  ++ R V Q+  +   G++   G  
Sbjct: 299 SVWTDADQVLSYDILNELSYLDMVVSETLRMYPP-GMLTRAVTQDCVI--QGRRFRKGNA 355

Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508
           +++  Y LH  P+++P P +F+P+ F  E   +R+  A++PFSAGPR+CVG ++++++LK
Sbjct: 356 ILMDVYSLHHDPELWPEPERFNPERFTAEAKQSRNPCAYLPFSAGPRNCVGMRFSLMELK 415

Query: 509 VILSTILRNF 518
           + L+ IL+ +
Sbjct: 416 LALTRILKKY 425



 Score = 43.6 bits (98), Expect = 0.014
 Identities = 48/232 (20%), Positives = 103/232 (44%), Gaps = 18/232 (7%)

Query: 61  NALEFVGGSADIFRN---IVQKSADYD--HESVVKIWIGPRLLVFLYDPRDVEVILSS-- 113
           N L F+G   D  ++   I  + A+Y   +  V  +++     + + DP  ++ +L    
Sbjct: 5   NHLPFIGTLIDTIKHGGDIRLQFAEYSRTYGRVYGLYLFGSPTIVINDPDILKEVLVKEF 64

Query: 114 HVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV 173
           H + D+   +   +P+  + +  + G+ W   R  ++P F  + +K  + L N +   ++
Sbjct: 65  HSFHDRPAFFPMPEPF-DSMMFFAEGETWHRVRTTVSPIFSAHKMKMVLPLMNNSCDIMM 123

Query: 174 DKLKKEASN---FDCHDYMSECTVEILLETAMGVSKSTQ---DQSGFEYAMAVMKMCDIL 227
            KL++ A     F+ +      T++ +L    G+  S Q   D   F  A + ++     
Sbjct: 124 SKLQQAAEKGEPFNMYRMGQSLTMDFILRIVFGIESSVQHNYDDPAFVAARSALEASTFQ 183

Query: 228 HLRHTKIWLRPDLLFK-FTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKK 278
            +    + + P  + K F+    + TK  +++  +T+KVI  KK +  S +K
Sbjct: 184 KIAGAVVGMMPKPIKKMFSRVFFSHTK--ELVE-MTEKVIAAKKTQENSTRK 232


>UniRef50_O16156 Cluster: Cytochrome P450 30; n=1; Mercenaria
           mercenaria|Rep: Cytochrome P450 30 - Mercenaria
           mercenaria (Northern quahog) (Venus mercenaria)
          Length = 515

 Score =  131 bits (316), Expect = 5e-29
 Identities = 70/212 (33%), Positives = 122/212 (57%), Gaps = 5/212 (2%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           ++DEE+       M  G+DTTA   S+ +  +  + + Q+K+IEE+D   G+S+   T+ 
Sbjct: 307 LTDEEVLLNSIIFMVAGYDTTATTLSWIVYDLVTNTECQEKLIEEIDAEIGESE--TTYD 364

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
           +  +++YL+  + ETLR++PP   I R   +++ +  NG +I  G     +   LH  P+
Sbjct: 365 NVFKLRYLDMVVNETLRMHPPAQRINRLALEDVKI--NGLQILKGMDCTFSILALHYMPE 422

Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVI 521
            + NP K+DP+ F PE  AN + YA++PF  GPR+C+G++ A+L++K  +  +L+ FR+ 
Sbjct: 423 YWENPYKYDPERFAPENQANINQYAYMPFGQGPRNCIGKRLALLEVKATVVVLLQKFRLH 482

Query: 522 SDLKESDFKLQADIIL-KRAEGFQVRLQPRKR 552
              K       +D+ L K A+   VRL+ R +
Sbjct: 483 KTDKLQVPMPVSDVGLGKPAKPVFVRLEKRSK 514


>UniRef50_A1UDQ6 Cluster: Cytochrome P450; n=10; Mycobacterium|Rep:
           Cytochrome P450 - Mycobacterium sp. (strain KMS)
          Length = 474

 Score =  130 bits (313), Expect = 1e-28
 Identities = 67/196 (34%), Positives = 116/196 (59%), Gaps = 7/196 (3%)

Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396
           ++G ++SD++I  ++   M  GHDTTA   ++ L  +G H DIQD+V  E   +    DR
Sbjct: 267 ETGRSLSDDDICNELLVFMLAGHDTTATLLTYALWALGHHPDIQDRVAAEACAL---GDR 323

Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456
             T  D   + Y  + L E+LRL PP   + R   +++ +  +G ++ AG+ + I  Y +
Sbjct: 324 LPTPDDVGRLGYTVQVLNESLRLCPPAAGVGRMALRDVEV--DGYRVEAGSLVGIGIYAV 381

Query: 457 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 516
           HR P+++  P +FDP+ F PE   +R  + F+PF+ GPR+C+G+ +AML+  + L+T++R
Sbjct: 382 HRDPELWDRPLEFDPERFSPENVKDRDRWQFIPFAGGPRACIGQHFAMLEATLALATLIR 441

Query: 517 NFRVISDLKESDFKLQ 532
           +  + S   + DF L+
Sbjct: 442 SHEIRS--IDDDFPLE 455


>UniRef50_A7RSL1 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 510

 Score =  130 bits (313), Expect = 1e-28
 Identities = 63/199 (31%), Positives = 115/199 (57%), Gaps = 7/199 (3%)

Query: 325 RLAFLDLLLESSQS-----GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           R   LDL+LE++ S     G A+S + I       +  GH+TT++  +F    +  +  I
Sbjct: 282 RKDMLDLMLEAAASDNTDGGKALSLDAIIANTIVFLLAGHETTSSTIAFASYFLAKNPKI 341

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q+K+ +E+D ++   +   ++    ++ YLE  + ETLRL PP   + R+  +   +  N
Sbjct: 342 QEKLQQEIDSVWSGEEEMPSYDTVHDLPYLEMVISETLRLCPPGFAVIRECTKTCII--N 399

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
             +IP G+ ++ + Y +HR P  YP+P+ FDP+ F PE  A+R  YA++PF  GP +C+G
Sbjct: 400 KLRIPQGSRVLASVYSIHRDPKYYPDPDIFDPERFSPEGKASRDPYAYMPFGHGPHNCIG 459

Query: 500 RKYAMLKLKVILSTILRNF 518
            ++A +++K++L  +L+ +
Sbjct: 460 MRFAQMEIKLVLVRMLKRY 478



 Score = 41.9 bits (94), Expect = 0.043
 Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 3/88 (3%)

Query: 126 FKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDC 185
           F P L   L I  G++WR+ R  ++P F  + LK  + L N      + K+   A   + 
Sbjct: 123 FSPPLDKMLTILPGEEWRNLRHALSPNFSAHKLKGMVPLMNKACDVYMKKIACAAETGET 182

Query: 186 HDYMS---ECTVEILLETAMGVSKSTQD 210
            D M      T++I++  A GV    Q+
Sbjct: 183 IDVMKINPALTLDIIISCAFGVESDCQN 210


>UniRef50_A3RK60 Cluster: Cytochrome P450; n=2; Liposcelis
           bostrychophila|Rep: Cytochrome P450 - Liposcelis
           bostrychophila
          Length = 527

 Score =  130 bits (313), Expect = 1e-28
 Identities = 63/190 (33%), Positives = 101/190 (53%)

Query: 330 DLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQ 389
           +L +E ++S    S EE   Q       G +T++      L  + +  +IQ+KV  E+  
Sbjct: 306 ELEVEENRSDQKFSFEEAAAQAFIFFVAGFETSSTTMVLALYELALQPEIQEKVRNEIKT 365

Query: 390 IFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTL 449
           + G  +  +T++    M YL   + ETLR YP   +I RQ N++  +P +   IP GT+ 
Sbjct: 366 VLGKHNGKITYEAAFGMDYLGNVIDETLRKYPVAGVIIRQCNKDYKIPDSDMVIPKGTST 425

Query: 450 VIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKV 509
            I  Y LH     +PNP KFDPD F  E  + R  YA++PF  GPR C+G ++ +++ +V
Sbjct: 426 HIPIYSLHYDSKYFPNPEKFDPDRFTEEVKSQRPRYAYLPFGEGPRHCIGMRFGLMQTRV 485

Query: 510 ILSTILRNFR 519
            L  +L N++
Sbjct: 486 GLIELLLNYK 495



 Score = 36.7 bits (81), Expect = 1.6
 Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 138 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD---CHDYMSECTV 194
           +G KWR+ R  + PTF    +K    +   + R ++  L+  A N D     D ++  T 
Sbjct: 129 SGSKWRNLRAKLTPTFTSGKMKMMFPILVESGREMISILEPNAINKDIVEMKDILARFTT 188

Query: 195 EILLETAMGVSKSTQDQSGFEY 216
           +++   A G+  ++      E+
Sbjct: 189 DVIASCAFGIDSNSLKNPDTEF 210


>UniRef50_UPI0000D56564 Cluster: PREDICTED: similar to Probable
           cytochrome P450 6a17 (CYPVIA17); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Probable cytochrome
           P450 6a17 (CYPVIA17) - Tribolium castaneum
          Length = 471

 Score =  129 bits (312), Expect = 2e-28
 Identities = 73/224 (32%), Positives = 122/224 (54%), Gaps = 8/224 (3%)

Query: 321 GQKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 380
           GQ  R  FL +L+E  +    I+ +EI  Q    +  G  T+    +F L  +  HQDIQ
Sbjct: 243 GQTGRNDFLQVLVEMEKK-FEITIDEIAAQCFIFLIAGMSTSPTAMTFALYELARHQDIQ 301

Query: 381 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS-N 439
           +KV +++ + FG     VT+    EMKYL +   ETLR+YPP   + R+  +   +P  +
Sbjct: 302 EKVRQDIAK-FGK----VTYDSLQEMKYLGQVFDETLRMYPPAAYLNRKCERNYEIPDGS 356

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G  +  GT + I    +H   D YP+P KFDP++F  E    R  +AF+PF  GPR C+G
Sbjct: 357 GIIVEKGTIVAIPVLGIHYDRDYYPDPEKFDPEHFSEENKRLRPNFAFLPFGEGPRICIG 416

Query: 500 RKYAMLKLKVILSTILRNFR-VISDLKESDFKLQADIILKRAEG 542
            ++ +++ K+ L ++L+ ++  +S+      K++ + ++  AEG
Sbjct: 417 MRFGLMQSKLGLVSLLKRYKFTVSEKTREPLKMKPNSLVLSAEG 460


>UniRef50_Q29AT3 Cluster: GA11819-PA; n=6; Diptera|Rep: GA11819-PA -
           Drosophila pseudoobscura (Fruit fly)
          Length = 513

 Score =  129 bits (312), Expect = 2e-28
 Identities = 64/210 (30%), Positives = 116/210 (55%), Gaps = 3/210 (1%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           IS E I  Q       G +TT + ++F L  +  + ++ +++  E+D+    +D  +T+ 
Sbjct: 303 ISLESITAQAFIFYIAGQETTGSTAAFVLFELAQYPELLERLQTEVDETLAKNDGHITYD 362

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
              +M++L+ C+ E+LR YP +P++ R+  Q+ T+P     IP GT +VI+ Y +H   +
Sbjct: 363 ALQKMEFLDLCVQESLRKYPGLPMLNRECTQDYTVPDTDHVIPKGTPVVISLYGIHHDAE 422

Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 520
            +P P  +DPD +  E + N    AF+PF  GPR C+ ++  +L  K+ +  +L+NF V 
Sbjct: 423 YFPEPETYDPDRY-SEENRNFSPTAFMPFGEGPRICIAQRMGLLNAKLAIINVLKNFNVE 481

Query: 521 ISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           +   ++ +F+  + I L    G +VRL  R
Sbjct: 482 VMSKRQLEFE-NSGIALLPKNGVKVRLSKR 510


>UniRef50_Q964R1 Cluster: Cytochrome P450 6j1; n=1; Blattella
           germanica|Rep: Cytochrome P450 6j1 - Blattella germanica
           (German cockroach)
          Length = 501

 Score =  129 bits (311), Expect = 2e-28
 Identities = 70/213 (32%), Positives = 112/213 (52%), Gaps = 3/213 (1%)

Query: 323 KKRLAFLDLLLESSQSGVAISD-EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           +KR   LD L+E   S  +  D ++   Q    +  G  T++   +F L  + +HQDIQ 
Sbjct: 270 EKRNDLLDYLMELRTSETSKLDGDDFVAQAFGFLVAGFHTSSMTLTFALYELSVHQDIQT 329

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
               E+  +     + VT+    +MKYL+  + ETLR YP +P + R+  ++  L  +  
Sbjct: 330 TARTEIKDVLEHHKKKVTYYSIKDMKYLDMVVNETLRKYPAIPFLDRRCQEDYPLTQD-L 388

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            +PAGT + I  Y LH     +P+P KFDP+ F  +   N  ++A++PF  GPR+C+G +
Sbjct: 389 MLPAGTGVYIPVYALHHDSKYFPSPAKFDPERFSEKNKQNIPHFAYMPFGEGPRNCIGMR 448

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQAD 534
           +  +++K  L  IL NF V S  KE+   L  D
Sbjct: 449 FGSMQVKAALIHILSNFEV-SPCKETRIPLIID 480


>UniRef50_UPI00015B60B4 Cluster: PREDICTED: similar to cytochrome
           P450; n=3; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 533

 Score =  128 bits (310), Expect = 3e-28
 Identities = 62/178 (34%), Positives = 105/178 (58%), Gaps = 2/178 (1%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           IS  E   Q       G +TT++  ++ L  + ++ +IQ+KV  E+D+ F   D  +T++
Sbjct: 312 ISLSEAIGQAFIFYLAGFETTSSTITYCLYELALNPEIQEKVQAEIDE-FSKRDGGITYE 370

Query: 402 D-TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 460
             + +MKYL    +ETLR +P +P + R+  ++  +P+   +I  GT L+I    +HR P
Sbjct: 371 IMSNDMKYLHMVFLETLRKHPSIPFLNRECIEDCDIPNTNFRIEKGTKLLICMNAMHRDP 430

Query: 461 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518
           D++P+P KFDP  F  E  A+R  Y ++PF  GPR+C+G ++ ML+ K+ L  +L N+
Sbjct: 431 DIFPDPEKFDPFRFTKENIASRQPYTYLPFGDGPRACIGIRFGMLQTKIALIGLLSNY 488



 Score = 41.5 bits (93), Expect = 0.057
 Identities = 35/161 (21%), Positives = 64/161 (39%), Gaps = 5/161 (3%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHV--YID 118
           NA   + G   I   + QK  +     V  I++  + ++ + DP  +++IL      + +
Sbjct: 54  NAFPLISGKVSIGNLMRQKYNEGKKYPVYGIYMFHKPILLINDPNVIQLILIKEFNKFCN 113

Query: 119 KAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDL---FNANSRAVVDK 175
           +   +      L   L    G++WR  R  + PTF    LK    L      N   V D+
Sbjct: 114 RGLYFNDKVDTLSLNLFFLPGERWRQLRTKLTPTFTSGKLKQMYPLLLEIGDNLIRVCDQ 173

Query: 176 LKKEASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGFEY 216
           + K+ +  +  D +   T + +   A GV   + D    E+
Sbjct: 174 IIKKDNIVEFKDLIGRYTTDSISSIAFGVDCQSLDNGSSEF 214


>UniRef50_Q0LK65 Cluster: Cytochrome P450; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Cytochrome P450 -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 454

 Score =  128 bits (310), Expect = 3e-28
 Identities = 61/182 (33%), Positives = 103/182 (56%), Gaps = 4/182 (2%)

Query: 337 QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDR 396
           ++G  +S   ++++  T+ F GH+TTA   SF    +  + D+ +++  E+D + GD+  
Sbjct: 246 ETGEPMSTVLLRDEAITVFFAGHETTARTLSFLWYALANNPDVAERMQAEIDSVLGDA-- 303

Query: 397 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 456
             T     ++ Y  + + ETLRLYP  P+ AR           G K+P G+ + I  Y  
Sbjct: 304 APTLDHLKQLPYTLQVIKETLRLYPAAPMYARDAVASDEFA--GIKVPVGSRMTIMPYLT 361

Query: 457 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 516
           HR PD +  P +FDPD +LPER A RH +A+ PF+AG R C+G  +++ +  V+++ + R
Sbjct: 362 HRHPDFWDKPLRFDPDRWLPEREALRHPFAYHPFAAGQRICIGNNFSLFESHVVVAMLAR 421

Query: 517 NF 518
           +F
Sbjct: 422 HF 423



 Score = 41.9 bits (94), Expect = 0.043
 Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 10/138 (7%)

Query: 68  GSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSH--VYIDKAEEYRF 125
           G+   F +  ++  D  H     + +G + +  +  P  V  ++      Y  KA     
Sbjct: 27  GTLQFFESTWRRYGDLAH-----LQLGSKDMFLVVHPDHVRRVMVEQRDTYSKKASYEGV 81

Query: 126 FKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLF---NANSRAVVDKLKKEASN 182
            K  LG+GL+ STG  WR  RKL+AP F    +++++ +     A  R       K+   
Sbjct: 82  RKLLLGDGLVASTGSLWRRQRKLMAPFFTPRAIETYLPIIVEDGAWFRERWSAAAKQGEP 141

Query: 183 FDCHDYMSECTVEILLET 200
            D    MS  T  I+L++
Sbjct: 142 LDILTEMSVLTASIILKS 159


>UniRef50_Q9KFA6 Cluster: Cytochrome P450 hydroxylase; n=1; Bacillus
           halodurans|Rep: Cytochrome P450 hydroxylase - Bacillus
           halodurans
          Length = 453

 Score =  128 bits (309), Expect = 4e-28
 Identities = 63/213 (29%), Positives = 127/213 (59%), Gaps = 8/213 (3%)

Query: 339 GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPV 398
           G  ++D ++++++ T+   GH+TTA   S+   ++  H  +++K+ +E+ Q+ G+  RP 
Sbjct: 248 GSYMTDRQLRDEIITLFLAGHETTANTLSWAFYLLSQHPHVEEKLYQEVSQVLGN--RPA 305

Query: 399 TFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR 458
           T +D  ++ Y E  + ETLR+ P V +I+R+  +++TL      I AG+ ++I+ + +HR
Sbjct: 306 TLEDMPKLSYAEHVIKETLRVQPTVWLISRRAEKDVTL--GDYHISAGSEIMISQWGMHR 363

Query: 459 RPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRN 517
            P  + +P  F P+ +  + + N+   Y + PF  GPR C+G ++A+++  +I++TI+R 
Sbjct: 364 NPRYFNDPLTFLPERW--DNNDNKPSKYVYFPFGGGPRVCIGERFALMEATLIMATIVRE 421

Query: 518 FRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
           FR +  + E   K++  I L+   G  ++L+ R
Sbjct: 422 FR-MELVDELPIKMEPSITLRPKHGVTMKLRKR 453



 Score = 35.1 bits (77), Expect = 4.9
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 1/70 (1%)

Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMS 190
           GNGLL S G  W   R+L  P FH   +  + D        +++      +  D +D M 
Sbjct: 86  GNGLLTSEGSFWLRQRRLSQPAFHPKRIADYADTMVGYCERMLNTWMDNDTR-DINDEMM 144

Query: 191 ECTVEILLET 200
           + T+ I  +T
Sbjct: 145 QLTMAIATKT 154


>UniRef50_Q9VGB3 Cluster: Probable cytochrome P450 313a3; n=2;
           Drosophila melanogaster|Rep: Probable cytochrome P450
           313a3 - Drosophila melanogaster (Fruit fly)
          Length = 492

 Score =  128 bits (309), Expect = 4e-28
 Identities = 73/222 (32%), Positives = 126/222 (56%), Gaps = 4/222 (1%)

Query: 322 QKKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 381
           Q +  + ++  +E  ++G  +S EE++ +  + +    +TT       L ++ +  + QD
Sbjct: 263 QPEITSVINKAIELHRNG-EMSREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQD 321

Query: 382 KVIEELDQIFGDS-DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 440
            V +EL ++F  + D  VT+ D   M +LER + ETLRL P VP   R+  ++  L S+G
Sbjct: 322 TVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRL-SSG 380

Query: 441 KKIPAGTTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
             IP G  + I  +  HR  D +  +P+ F+PD+FLP+   +RH YA++PFS G R+C+G
Sbjct: 381 VVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRHPYAYIPFSKGRRNCIG 440

Query: 500 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIILKRAE 541
            KY ++  K+ LS ILRN +V +  +  D +   +I ++ A+
Sbjct: 441 WKYGLMSSKLALSKILRNCKVSTSFRYEDLEFVDNIGMELAQ 482



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 60/229 (26%), Positives = 99/229 (43%), Gaps = 15/229 (6%)

Query: 18  INLFYVLLVPAVILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIV 77
           ++ F +LL   V  W  Y+  SRRRLY +  K+           A E++  +     +I 
Sbjct: 1   MDTFQLLLAVGVCFWI-YFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLI-TYKRKMSIR 58

Query: 78  QKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEY-RFFKPWLGNGLLI 136
            K  D  + S   +W+GP   V   DP+  E I  S   ++++  + +      G+GLL 
Sbjct: 59  TKYMDI-YGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLS 117

Query: 137 STGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV---DKLKKEASNFDCHDYMSECT 193
               KW   RK + P F  NVL SF+ +FN+ ++ +V   D L  +       D +   +
Sbjct: 118 LEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEK-KVRDDIVRWS 176

Query: 194 VEILLETAMGVS-------KSTQDQSGFEYAMAVMKMCDILHLRHTKIW 235
             I  +T +G         K+      +E  M ++ M  +L   H KI+
Sbjct: 177 FRIATQTTVGTDVKKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKIF 225


>UniRef50_UPI00015B595F Cluster: PREDICTED: similar to cytochrome
           P450; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 538

 Score =  128 bits (308), Expect = 5e-28
 Identities = 59/173 (34%), Positives = 97/173 (56%), Gaps = 1/173 (0%)

Query: 346 EIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLE 405
           E   QV      G +TT+   ++ L  +  + ++Q+K+ EE+D++  +S     + + + 
Sbjct: 333 EAAAQVFVFFIAGFETTSTTVTYCLHELAKYPEVQEKLQEEIDEV-ANSPEGFNYDNIMN 391

Query: 406 MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPN 465
           MKYL+    ETLR +PPVP + R   ++  +P    +IP G  L I+   L R PD+YP 
Sbjct: 392 MKYLDMTFNETLRKHPPVPFVNRLCTKDYQIPGTDLRIPKGMRLAISVSGLQRDPDIYPE 451

Query: 466 PNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518
           P KF+P  F  E  A R  Y F+PF  GPR C+ ++ A+++ K+ L+T+L  +
Sbjct: 452 PEKFEPLRFSKENLAQRSAYCFLPFGEGPRICIAKRIALMQGKLALATLLSKY 504


>UniRef50_Q629N7 Cluster: Cytochrome P450-related protein; n=24;
           Burkholderia|Rep: Cytochrome P450-related protein -
           Burkholderia mallei (Pseudomonas mallei)
          Length = 1373

 Score =  128 bits (308), Expect = 5e-28
 Identities = 69/226 (30%), Positives = 130/226 (57%), Gaps = 8/226 (3%)

Query: 329 LDLLLESSQ--SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           + LLL +    +G  ++ +E+ ++V T+   GH+TT AG ++ L  +  H  +  ++ +E
Sbjct: 230 ISLLLNARDPDTGAPMTQQEVHDEVMTVFLAGHETTGAGLAWALYALAQHPAVLRQLRDE 289

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           LD   G   R  T QD  ++ YL + + E LR+YPP+    R + ++  +   G +IPA 
Sbjct: 290 LDARLGG--RAPTVQDFEQLPYLSQVVDEVLRVYPPIWGFTRDLVEDDEI--GGYRIPAR 345

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
           +++ ++ Y  HR P  + NP+ FDP+NF  +  A RH + + PF  G R C+G + A+L+
Sbjct: 346 SSVFMSPYVTHRHPAFWRNPDAFDPENFASDAPA-RHRFVYFPFGGGMRKCIGFQTALLQ 404

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKR 552
           ++V+++ + ++F  ++ L     +L A I L+   G ++ ++PR+R
Sbjct: 405 MRVLVAVVAQHFD-LNALPGHPIELGATISLRPVHGIRLIVKPRER 449



 Score = 44.8 bits (101), Expect = 0.006
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 1/63 (1%)

Query: 93  IGPRLLVFLYDPRDVEVILS-SHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAP 151
           +GP +   L  P  ++ +L  +H    +   Y  FK + G+GLL + G+ WR HR+++ P
Sbjct: 45  LGPFVTHALAHPDHIQYVLQENHRNYVRGRFYDNFKMFFGDGLLTTDGEFWRRHRRVVQP 104

Query: 152 TFH 154
            FH
Sbjct: 105 LFH 107


>UniRef50_Q5W1K8 Cluster: Cytochrome P450 CYP6AX1 protein; n=2;
           Hemiptera|Rep: Cytochrome P450 CYP6AX1 protein -
           Nilaparvata lugens (Brown planthopper)
          Length = 514

 Score =  127 bits (307), Expect = 7e-28
 Identities = 60/186 (32%), Positives = 104/186 (55%), Gaps = 1/186 (0%)

Query: 335 SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDS 394
           +++S V + D+ +          G +TTA   +F +  + ++Q+IQDK+ +E+   F + 
Sbjct: 295 NNESHVILDDKLLAANTFIFFIAGFETTATTLTFSMYELAVNQEIQDKLRQEVQTTF-EK 353

Query: 395 DRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATY 454
              + +  T +M YL+R + ETLR YP    + R+  +   +P    K+  G  +VI  Y
Sbjct: 354 YGAINYDSTKDMDYLDRVISETLRKYPIAGSLIRRCTKAWQVPGAKGKLEVGDRVVIPVY 413

Query: 455 KLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTI 514
            +H  P  YP+P KFDP+ F PE   +R    ++PF  GPR C+G ++A+ +LK  LS+I
Sbjct: 414 PIHHDPKYYPDPQKFDPERFTPENKRSRPPCTYMPFGDGPRICIGARFALQELKTTLSSI 473

Query: 515 LRNFRV 520
           L ++++
Sbjct: 474 LLHYKL 479



 Score = 38.3 bits (85), Expect = 0.53
 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 8/130 (6%)

Query: 82  DYDHESVVKIWIGPRL-LVFLYDPRDVEVILSS---HVYIDKAEEYRFFKPWLGNGLLIS 137
           DY  +     W+  R  L+ + DP  ++ IL     H Y D+          L   LL  
Sbjct: 71  DYFADDAYGGWLANRSPLLMVKDPELIQQILVKDFVHFY-DRGTTVDMKLDPLNANLLNM 129

Query: 138 TGQKWRSHRKLIAPTFHLNVLKSFIDLFNA---NSRAVVDKLKKEASNFDCHDYMSECTV 194
           TGQ+W++ R+ + P F    LK     FN    +   ++D+   +    D  + MS+   
Sbjct: 130 TGQRWKALRQKLTPAFSSGKLKLMSPQFNECVDDLCGLIDEKSNKKELIDVQESMSKLAT 189

Query: 195 EILLETAMGV 204
           +++   A G+
Sbjct: 190 DVIGSCAFGL 199


>UniRef50_UPI0000D56E82 Cluster: PREDICTED: similar to Cytochrome
           P450 9c1 (CYPIXC1); n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to Cytochrome P450 9c1 (CYPIXC1) -
           Tribolium castaneum
          Length = 480

 Score =  127 bits (306), Expect = 9e-28
 Identities = 71/231 (30%), Positives = 127/231 (54%), Gaps = 13/231 (5%)

Query: 329 LDLLLESSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           + L+LE+++     ++D++I  Q  T  F G +T A   SF    + IH +IQ K+  E+
Sbjct: 254 IHLMLEANKGQANQLTDDDIVAQAMTFFFAGFETVATACSFMAYELAIHPEIQQKLQAEI 313

Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL-PSN----GKK 442
           D + G     VT++  L MK+L++ + E+LRL+PP   I R   +   + P N    G  
Sbjct: 314 DSVGG-----VTYESLLSMKFLDQVVSESLRLWPPGFQIERMCTKSYKIEPKNHNEKGIV 368

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           +  G +L+I    LH  PD++P P++FDP+ F     +     +++PF  GPR+C+  ++
Sbjct: 369 LEEGVSLIIPVIALHHDPDLFPEPDRFDPERFSEANRSQIVPGSYLPFGVGPRNCIASRF 428

Query: 503 AMLKLKVILSTILRNFRVIS-DLKESDFKLQA-DIILKRAEGFQVRLQPRK 551
           A+L++K +   +L  F ++  D  +   KL    + L+  +GF++ ++PRK
Sbjct: 429 ALLEIKTLFFHMLSKFDIVPIDTTQIPLKLSTKKMHLEPEKGFRLGIRPRK 479



 Score = 46.0 bits (104), Expect = 0.003
 Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 1/108 (0%)

Query: 128 PWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK-KEASNFDCH 186
           P LG  LL+  GQ W+  R  ++P +  N LK+   L    ++  V   K +E    D  
Sbjct: 106 PILGKSLLMLNGQDWKQMRATLSPAYTTNKLKNMHQLMTECAQNFVGHFKGREKVAVDMK 165

Query: 187 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKI 234
           D  +  T +++  TA G+   + +Q    + +    +     ++  KI
Sbjct: 166 DIFTRFTTDVIASTAFGIKTDSLNQPNNRFFLMAKSLSKFGFIQVVKI 213


>UniRef50_A0NQ01 Cluster: Cytochrome P450; n=1; Stappia aggregata
           IAM 12614|Rep: Cytochrome P450 - Stappia aggregata IAM
           12614
          Length = 476

 Score =  127 bits (306), Expect = 9e-28
 Identities = 72/222 (32%), Positives = 123/222 (55%), Gaps = 8/222 (3%)

Query: 332 LLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390
           LLE+  ++G  +S + I  +   I   GH+TTA   ++   ++      + K+  ELD +
Sbjct: 260 LLEARDENGEPLSRDAIISEAAVIFMAGHETTANTLAWAWFLLSQCDKSRAKLQAELDTV 319

Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450
              + R  TFQD   + Y +  + ETLRLYPPVPI+AR+   + ++   GK +P G+ ++
Sbjct: 320 L--AGRSPTFQDVPNLPYTKAVIEETLRLYPPVPILAREAMADTSI--GGKSVPKGSLVM 375

Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVI 510
           +  + +HR P ++  P+ FDP  FL  +S   + Y +VPFS GPR C G ++ M +  + 
Sbjct: 376 VVPWLMHRNPVLWSKPDVFDPGRFLNPKSKKPNKYGYVPFSIGPRICAGLQFGMTEAILS 435

Query: 511 LSTILRNFRVISDLKE-SDFKLQADIILKRAEGFQVRLQPRK 551
           L+ + ++F +   LKE +D +  A + L+  E   + L PR+
Sbjct: 436 LAILAQDFEL--KLKEGTDVQPVARLTLRPGENLPMTLHPRR 475



 Score = 41.5 bits (93), Expect = 0.057
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 127 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSF--IDLFNANSRAVVDKLKKEASNFD 184
           +P LG+GL IS  + W   RK++AP  H + ++ F  I +     +     ++ E +  D
Sbjct: 104 QPLLGDGLFISDTETWAKRRKVVAPIIHGSRVRGFAPIMIETIEEKRADWAVQGEGAEVD 163

Query: 185 CHDYMSECTVEILLET----AMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWL 236
               M+  T EI+  T     +G   + +   GF      +   DIL L     WL
Sbjct: 164 ALADMAHLTAEIICRTIFGRQLGKDYAAEVVQGFSDYQRHIDQIDILSLFGLPEWL 219


>UniRef50_Q6PW74 Cluster: Cytochrome P450 CYP331A1; n=1; Capitella
           capitata|Rep: Cytochrome P450 CYP331A1 - Capitella
           capitata
          Length = 549

 Score =  127 bits (306), Expect = 9e-28
 Identities = 96/403 (23%), Positives = 192/403 (47%), Gaps = 17/403 (4%)

Query: 131 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD-CH--D 187
           G  + ++ GQ+W+  R +  PTF    LK   +L N  SR ++ KL+  A+  D C    
Sbjct: 117 GCSMFMAQGQRWKRLRTITNPTFTAAKLKHSTELMNRKSRTLLKKLEAIATKGDKCRILP 176

Query: 188 YMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDY 247
            + + T++++ E+A G+  + Q+ +G      + +  +   LR +     P+L F     
Sbjct: 177 LLQDLTLDVIGESAFGIEVNAQEIAGNPSLSMLKRNREQNTLRKSFYATLPELRFTIYHC 236

Query: 248 AKNQTKLLDI----IHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLS 303
                K + +    I     KV++ +K +    + P +L +    +E +T    S+E  +
Sbjct: 237 LAFFAKFVSVPRFQILESMGKVLEMRKIQ--PQRNPPDLMQLMVDAE-ATNHHGSLEIFA 293

Query: 304 FGQSSGLKXXXXXXXXXGQKK-RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTT 362
                                 +++  D    +      ++ +EIK Q    +  G++TT
Sbjct: 294 DDDDDDDDDDYAKASPDESIDIQISEADRERHARTRKKKLTADEIKSQGFLFLLAGYETT 353

Query: 363 AAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYP- 421
           +   +     +  + D Q  + EE++ I  D D  +T++    + YL+  L ETLR+YP 
Sbjct: 354 SNTLACCSHALANNPDKQQLLYEEVNSIIQD-DEELTYEKVKALPYLDMVLRETLRMYPI 412

Query: 422 PVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY--PNPNKFDPDNFLPERS 479
              ++ R+  +  T+  N   +P    +    + +H   +++   +P  F+P+ FLP+R 
Sbjct: 413 GSQVVTRRCVETCTI--NDLVVPRDMAIHANVWDVHYNANIWGATDPKIFEPERFLPDRK 470

Query: 480 ANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 522
           A RH  A++PF AGPR+C+G ++A+L+ +++L+ +++ FR++S
Sbjct: 471 ARRHPLAWLPFGAGPRNCIGLRFALLEAQIVLAKLIKKFRIVS 513


>UniRef50_Q8WQM9 Cluster: Cytochrome P450 CYP6M1; n=7;
           Culicidae|Rep: Cytochrome P450 CYP6M1 - Anopheles
           gambiae (African malaria mosquito)
          Length = 503

 Score =  126 bits (305), Expect = 1e-27
 Identities = 60/199 (30%), Positives = 111/199 (55%), Gaps = 4/199 (2%)

Query: 324 KRLAFLDLLL----ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           +R  F+DL++    ++     A++  E+  Q     F G +T++   ++ L  + ++ ++
Sbjct: 266 QRNDFMDLMIRMLRDTENPEEALTFNEVAAQAFVFFFAGFETSSTLLTWTLYELALNPEV 325

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q+K  + + ++    +  +T+    +MKYL++ L E+LR YPPVP+  R   Q+  +P  
Sbjct: 326 QEKGRQCVQEVLAKHNGEMTYDAIHDMKYLDQILKESLRKYPPVPMHFRMTAQDYRVPDT 385

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
              I AGT L I  + + R   ++P P KFDP+ F  E  A RH +A+ PF  GPR C+G
Sbjct: 386 DSVIEAGTMLFIPIFSIQRDASLFPEPEKFDPERFSAEEEAKRHPFAWTPFGEGPRVCIG 445

Query: 500 RKYAMLKLKVILSTILRNF 518
            ++ M++ ++ L+ +L+ F
Sbjct: 446 LRFGMMQARIGLAYLLQGF 464


>UniRef50_Q162V4 Cluster: Cytochrome P450 family protein, putative;
           n=1; Roseobacter denitrificans OCh 114|Rep: Cytochrome
           P450 family protein, putative - Roseobacter
           denitrificans (strain ATCC 33942 / OCh 114)
           (Erythrobactersp. (strain OCh 114)) (Roseobacter
           denitrificans)
          Length = 451

 Score =  126 bits (304), Expect = 2e-27
 Identities = 64/195 (32%), Positives = 110/195 (56%), Gaps = 8/195 (4%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           F  + +   + G   S++EI    + ++   HDTTA   +  ++ +G H D Q ++I+E+
Sbjct: 235 FSQMCMAKDEDGKGWSEDEILNHFNLLIMAAHDTTATSLTVIMAALGTHGDWQQRLIDEV 294

Query: 388 DQIFGDSDRPVTFQDTL-EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           D + GD D     ++ L +MK  ++   E LRL PPVP I R   ++     +G  IPAG
Sbjct: 295 DGL-GDGDLD---EEALGQMKETDKVFREALRLVPPVPFIPRMATRDFHW--HGYDIPAG 348

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCVGRKYAML 505
           T+L +        P+++ NP +FDPD F P+R+ +R H +A+ PF  G   C+G  +A +
Sbjct: 349 TSLALNPGVTMLSPELFSNPTQFDPDRFAPDRAEDRIHRFAWTPFGGGAHKCIGMHFATM 408

Query: 506 KLKVILSTILRNFRV 520
           ++K+ ++T+LR  R+
Sbjct: 409 QVKLFIATLLRQRRI 423


>UniRef50_Q3IR83 Cluster: Unspecific monooxygenase; n=1;
           Natronomonas pharaonis DSM 2160|Rep: Unspecific
           monooxygenase - Natronomonas pharaonis (strain DSM 2160
           / ATCC 35678)
          Length = 448

 Score =  126 bits (304), Expect = 2e-27
 Identities = 68/207 (32%), Positives = 116/207 (56%), Gaps = 9/207 (4%)

Query: 344 DEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDT 403
           + +I+++V T +  GH+TTA   ++ L ++  H + + +V +E D+  GD   P T  D 
Sbjct: 246 ENQIRDEVATFLIAGHETTALSLTYTLCLLSWHPEARRRVRQEADEALGDG--PPTHDDL 303

Query: 404 LEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 463
            E+ Y  R   E LRLYPP   + RQ N ++TL      IP G+ +++  + +HR    +
Sbjct: 304 AELTYTRRVYDEALRLYPPAWGVFRQANGDVTL--GQYTIPDGSAVIMPLWSIHRDGSYF 361

Query: 464 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 523
             P+ FDPD +  ER   R   A+ PFS+GP +C+GR +A+    ++L+ ++R+F +  D
Sbjct: 362 EQPDTFDPDRW--ERRTPRAVDAYRPFSSGPHACIGRGFALAGSTLVLARLVRDFDI--D 417

Query: 524 LKESDF-KLQADIILKRAEGFQVRLQP 549
           + ES    L+    L+ A+G +  +QP
Sbjct: 418 VPESALDDLRLTPTLRPADGVEATIQP 444



 Score = 38.7 bits (86), Expect = 0.40
 Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 13/221 (5%)

Query: 61  NALEFVGGSADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKA 120
           NAL F     D FR +    A +D  + V I   P L+V L  P  V   L       + 
Sbjct: 15  NALRF---GTDTFRFLEGIQARFDDGTSVSIPGRPPLVV-LTGPDLVGEALDRPEDFPRV 70

Query: 121 EEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK-LKKE 179
                      NGL+ S G  W   R ++AP+F    + ++ +       A  D+     
Sbjct: 71  PAQDAVTMIAENGLVQSEGALWSQQRSVMAPSFSGEQVTAYANTTGRRIEARADQWAAAG 130

Query: 180 ASNFDCHDYMSECTVEILLETAMGVSKSTQDQSGF-EYAMAVMKMCDILHLRHTKIWLRP 238
           A   D H  M+  TV +  E  +G    T+    F E+     +  +         W+  
Sbjct: 131 ARTTDLHREMTSLTVRVASEILLGEDIGTERADQFHEWMQVAGEEFEFGIETVLPDWVPT 190

Query: 239 DLLFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKP 279
               +F   A         I  L++++I+R++E  A+G++P
Sbjct: 191 PTSGEFEQAAAG-------IRELSEQLIERRRESLAAGERP 224


>UniRef50_UPI0000DB7C31 Cluster: PREDICTED: similar to Probable
           cytochrome P450 6a14 (CYPVIA14); n=1; Apis
           mellifera|Rep: PREDICTED: similar to Probable cytochrome
           P450 6a14 (CYPVIA14) - Apis mellifera
          Length = 490

 Score =  126 bits (303), Expect = 2e-27
 Identities = 65/206 (31%), Positives = 109/206 (52%), Gaps = 3/206 (1%)

Query: 346 EIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLE 405
           E   Q       G +T++   +F L  +  +QDIQ+KV EE+  +    +  +T+    +
Sbjct: 285 EAAAQAYVFFLAGFETSSTTVTFCLYELAKNQDIQNKVREEIQTMI-KKNGDLTYNALND 343

Query: 406 MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPN 465
           M YL + + ETLR YPPV I+ R    ++ L +    IP GT + I  + LHR  +++PN
Sbjct: 344 MNYLHKVISETLRKYPPVVILNRICTNDVKLSTTDFCIPKGTCIAIPVFGLHRDSNIFPN 403

Query: 466 PNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKV-ILSTILRNFRVISDL 524
           P KFDP+ F  E    RH Y ++PF  GPR C+G ++ +++ K+ I++ +L+N       
Sbjct: 404 PEKFDPERFSEENIKTRHPYVYLPFGEGPRICIGLRFGLIQTKIAIINALLKNKFKFGPN 463

Query: 525 KESDFKLQ-ADIILKRAEGFQVRLQP 549
             S  + +   +IL    G  + ++P
Sbjct: 464 TPSTLEFEKGSLILIGKGGIHLNIEP 489



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 49/218 (22%), Positives = 91/218 (41%), Gaps = 9/218 (4%)

Query: 70  ADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHV--YIDKAEEYRFFK 127
           A+ FR+I + +    H  +V I++  +  + + DP  +  IL+     + D+   Y    
Sbjct: 40  AEFFRDIYEHNK---HHRLVGIYMLYKPYLIVNDPNLIRDILTKEFTNFHDRGIFYNEEV 96

Query: 128 PWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFD 184
             L   L    G+KWR+ R  + PTF    +K F  + N     +   L++EA   S  D
Sbjct: 97  DPLSGHLFQLPGKKWRNLRVKLTPTFTSGKIKQFFPILNEAGNILAKYLEEEARKGSTID 156

Query: 185 CHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKF 244
             D  +  + +I++  A G+S  +  +   E+     K+ D   L +  I   P +L  F
Sbjct: 157 VKDIFARYSTDIIMSVAFGISCDSFKEPNNEFRYWGKKIFDPKPLWNALILFAPQIL-NF 215

Query: 245 TDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKKPSNL 282
              +  +  +      + K+ +K ++      K   NL
Sbjct: 216 FSISYTEKSVTKFFTNMFKQTVKYRESNNIERKDFLNL 253


>UniRef50_Q70AR1 Cluster: Putative cytochrome P450; n=1;
           Streptomyces peucetius|Rep: Putative cytochrome P450 -
           Streptomyces peucetius
          Length = 448

 Score =  126 bits (303), Expect = 2e-27
 Identities = 62/202 (30%), Positives = 118/202 (58%), Gaps = 7/202 (3%)

Query: 321 GQKKRLAFLDLLL--ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378
           G  +    L +LL    S++G  +SD E+++++ TI+F G +TTA+  S+    +  H +
Sbjct: 222 GTSEHNDLLSVLLGARDSETGEYLSDTEVRDELSTILFAGAETTASTLSWTFYQLAEHPE 281

Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438
           ++ +++ E+  + GD  RPV+ +D  +++ + R L E +RL+  V ++ R+    + L  
Sbjct: 282 VEAELVAEIKDVVGD--RPVSIEDVPKLEAVRRVLDEVIRLHG-VTMLMRRTTAPVEL-- 336

Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
            G  +P GT +  + Y +HR P +Y +P++FDPD +LPER  +    A++PF AG R C+
Sbjct: 337 GGHLLPVGTEVGFSLYAMHRDPTLYDDPDRFDPDRWLPERRGDITRQAYIPFGAGNRKCI 396

Query: 499 GRKYAMLKLKVILSTILRNFRV 520
           G  +   +  + L+T+L  +++
Sbjct: 397 GDAFVWTEATIALATVLARWQL 418



 Score = 42.7 bits (96), Expect = 0.025
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 121 EEYRFF---KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK 177
           E+ RFF   +P  G+GL  + G+  R HR+LI P FH   +  + +  ++N+ A+ D   
Sbjct: 73  EKGRFFDRLRPLAGDGLATANGEVHRKHRRLIQPMFHPGRITMYAETMSSNALALADSW- 131

Query: 178 KEASNFDCHDYMSECTVEILLET 200
                 +    M++  +E L  T
Sbjct: 132 TAGQEVEMEQAMAQFAIETLATT 154


>UniRef50_Q3L917 Cluster: Cytochrome P450; n=1; Rhodococcus
           erythropolis PR4|Rep: Cytochrome P450 - Rhodococcus
           erythropolis (strain PR4)
          Length = 510

 Score =  126 bits (303), Expect = 2e-27
 Identities = 76/224 (33%), Positives = 120/224 (53%), Gaps = 7/224 (3%)

Query: 329 LDLLLESS--QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           LDL+L S+  ++G  +    I+ QV T +  G++TTA   +F L  +  H D+ D    E
Sbjct: 292 LDLMLHSADAETGEKLDPVNIRNQVFTFLVAGNETTAGTLAFALYFLSRHPDVADTARAE 351

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           +  +    + P  F+D   M+YL R + ETLRL+P  P   R+V  + TL      +P G
Sbjct: 352 VADVTA-GETPA-FEDVARMRYLRRVVDETLRLWPSAPGYFRKVRTDTTLGGR-YDMPKG 408

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
           + + +   +LHR P    +P  FDPD F PE    R  +A+ PF  GPR+C+GR++A+ +
Sbjct: 409 SWVFVLLPQLHRDPVWGEDPESFDPDRFKPENVKKRPAHAYRPFGTGPRACIGRQFALHE 468

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
             + L+ IL+ +   SD  E    ++  + LK   GF++ LQ R
Sbjct: 469 AVLALAIILQRYNFQSD-PEYKLDIRETLSLKPV-GFELSLQRR 510


>UniRef50_Q5KR92 Cluster: Cytochrome P450; n=1; Hodotermopsis
           sjoestedti|Rep: Cytochrome P450 - Hodotermopsis
           sjoestedti
          Length = 528

 Score =  125 bits (302), Expect = 3e-27
 Identities = 57/185 (30%), Positives = 102/185 (55%)

Query: 336 SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD 395
           S +   ++   I  Q       G +T++   +F L  + ++ DIQ+++  E+D +     
Sbjct: 307 SNASFDVTMNVIAAQAFVFYVAGFETSSTTMTFCLYELALNPDIQERLHAEIDTMLEKHG 366

Query: 396 RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYK 455
             +T++   EM+YL++ + ETLR YPPV I+ R+  + I L      +  G  +++    
Sbjct: 367 GNITYESIFEMEYLDKVVNETLRKYPPVVILTRECTKPIKLRRTDVTLEKGLQVLLPVLG 426

Query: 456 LHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515
           LH  P  YP+P +FDP+ F  E    R +++F+PF  GPR C+G ++A+++ KV L ++L
Sbjct: 427 LHHDPKYYPDPERFDPERFSEEEKKKRPHFSFLPFGEGPRMCIGMRFALMQTKVGLISLL 486

Query: 516 RNFRV 520
            N+ V
Sbjct: 487 SNYEV 491


>UniRef50_A7SCY4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 505

 Score =  125 bits (302), Expect = 3e-27
 Identities = 62/190 (32%), Positives = 110/190 (57%), Gaps = 3/190 (1%)

Query: 332 LLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIF 391
           +L  S     I+DEE+ +   T+   G +TTA   +F +  +G H  I+ ++ +E++++ 
Sbjct: 285 ILRMSDGDKPIADEEMIDNFLTLFIAGQETTANQLAFTVYEIGKHPQIEMRIQDEVERVL 344

Query: 392 GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVI 451
           G   R V ++D   +KY+ + L E+LRL+PP+  ++R   ++ITL  N   IP  T +++
Sbjct: 345 GGKSR-VDYEDLNLLKYVNQTLKESLRLHPPISGLSRMTTKDITL--NDVIIPKDTCVIL 401

Query: 452 ATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVIL 511
           + +  HR P+V+ +P+ FDP+ F  E         + PFS GPRSC+G   A  + KVI+
Sbjct: 402 SQFVTHRDPEVWNDPDTFDPERFALENVGRISSSMYFPFSLGPRSCIGNYLAQFEAKVIM 461

Query: 512 STILRNFRVI 521
           + + + F+V+
Sbjct: 462 ARLYQQFKVV 471


>UniRef50_Q27594 Cluster: Cytochrome P450 6a9; n=15;
           Schizophora|Rep: Cytochrome P450 6a9 - Drosophila
           melanogaster (Fruit fly)
          Length = 504

 Score =  125 bits (302), Expect = 3e-27
 Identities = 62/190 (32%), Positives = 108/190 (56%), Gaps = 3/190 (1%)

Query: 333 LESSQSG--VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390
           L  S+SG  V ++ EE+  Q       G +T++    F L  +  HQDIQD+V +E  ++
Sbjct: 282 LTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEV 341

Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK-KIPAGTTL 449
            G  +  +T++   +M YL++ + ETLRLY  +P++ R+  ++  +P + K  I  G  +
Sbjct: 342 IGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPV 401

Query: 450 VIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKV 509
           +I    +HR   +Y NPN F+PDNF PER   R    ++PF  GPR+C+G ++  ++ + 
Sbjct: 402 LIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARS 461

Query: 510 ILSTILRNFR 519
            L+ ++  F+
Sbjct: 462 GLALLINRFK 471


>UniRef50_A3RIC1 Cluster: Cytochrome P450; n=1; Bombyx mori|Rep:
           Cytochrome P450 - Bombyx mori (Silk moth)
          Length = 489

 Score =  125 bits (301), Expect = 4e-27
 Identities = 64/189 (33%), Positives = 100/189 (52%), Gaps = 1/189 (0%)

Query: 343 SDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQD 402
           +DE +  Q       G DTTA    F L  +  +  +  K+  E+D++F D  + + F+D
Sbjct: 281 TDELLAAQAFFFFVAGADTTANVMHFTLLELSSNPSVLKKLHAEIDEVFQDGKKTLNFED 340

Query: 403 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDV 462
             + KYLE  + ET+R YPP+ ++ R   +E  LPSN  +I   T  V+    LHR    
Sbjct: 341 MDKFKYLEMVVNETMRKYPPIGLLQRICTKETNLPSNNLRISKDTIAVVPVLALHRDERF 400

Query: 463 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVI- 521
           YP  + FDP  F PE     + ++F+PF  G R C+G K+A L+L+  L+ +LR + ++ 
Sbjct: 401 YPKSDAFDPQRFAPENFNEINKFSFLPFGEGNRVCIGAKFARLQLRAGLAWLLRKYTLVP 460

Query: 522 SDLKESDFK 530
            D K   F+
Sbjct: 461 QDYKPVKFE 469


>UniRef50_Q8MZK0 Cluster: Cytochrome P450; n=6; Culicidae|Rep:
           Cytochrome P450 - Anopheles gambiae (African malaria
           mosquito)
          Length = 505

 Score =  124 bits (300), Expect = 5e-27
 Identities = 62/210 (29%), Positives = 111/210 (52%), Gaps = 1/210 (0%)

Query: 334 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 393
           E+++    ++ +E+  Q     F G +T++   SF L  +  + DIQ++V  E+ +    
Sbjct: 287 ETTEGLQKLTLDEVAAQAFVFFFAGFETSSTTLSFALFELANNPDIQERVRAEMLEKLQL 346

Query: 394 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIAT 453
            D  +T+    EM YL++ + ETLR+YPPVP + R   Q   +      +   T L+I  
Sbjct: 347 HDGKITYDALKEMTYLDQVINETLRMYPPVPQLIRVTTQPYKVEGANVSLEPDTMLMIPI 406

Query: 454 YKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILST 513
           Y +H    +YP+P +FDPD F    +  RH +AF+PF  GPR+C+G ++ +L++K  +  
Sbjct: 407 YAIHHDASIYPDPERFDPDRFALAATHARHTHAFLPFGDGPRNCIGMRFGLLEVKFGIVQ 466

Query: 514 ILRNFR-VISDLKESDFKLQADIILKRAEG 542
           ++   R  +S+  +   ++     +  AEG
Sbjct: 467 MVSKLRFTVSERMQMPLRMSKTASILEAEG 496


>UniRef50_UPI0000D576F6 Cluster: PREDICTED: similar to Probable
           cytochrome P450 6a20 (CYPVIA20); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Probable cytochrome
           P450 6a20 (CYPVIA20) - Tribolium castaneum
          Length = 487

 Score =  124 bits (298), Expect = 8e-27
 Identities = 59/202 (29%), Positives = 110/202 (54%), Gaps = 2/202 (0%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           +S  EI  Q        ++T+    +F L  +  + DIQD+V  E+  +     +  +++
Sbjct: 277 MSINEIIAQCFIFFIAAYETSTTTLTFALYELAQNLDIQDRVRREITSVLLKHQK-YSYE 335

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
              EMKYL + + ET+R YPP   + R+  ++ T+P     I  G   +I+   +H   +
Sbjct: 336 AIAEMKYLNQIVDETMRKYPPFLYVVRRCTKDYTIPGEDVTIKKGIFALISILGIHHDEE 395

Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR-V 520
           +YPNP KFDPD F  E    RH YA++PF  GPR C+G+++A++++K  L+ +L  ++  
Sbjct: 396 IYPNPQKFDPDRFSKENKKMRHPYAYLPFGEGPRICIGKRFALMQIKFGLAALLEKYKFT 455

Query: 521 ISDLKESDFKLQADIILKRAEG 542
           +++  +   +++ D ++   +G
Sbjct: 456 LNEKTKVPLEIRTDTLVVAPKG 477


>UniRef50_Q9V4U7 Cluster: Probable cytochrome P450 6a14; n=10;
           Schizophora|Rep: Probable cytochrome P450 6a14 -
           Drosophila melanogaster (Fruit fly)
          Length = 509

 Score =  124 bits (298), Expect = 8e-27
 Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 1/176 (0%)

Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404
           E++  Q       G +T+++  S  L  + +  DIQ ++ EE++ +  + D      D L
Sbjct: 301 EQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVL 360

Query: 405 -EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 463
            +M YL++ L ETLR +P +P + R+  ++  +P++   +  G   +I  + +H  P++Y
Sbjct: 361 AQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIY 420

Query: 464 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519
           P P KFDP  F PE   NRH  A++PF  GPR+C+G ++  ++ K+ L ++LR F+
Sbjct: 421 PEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFK 476


>UniRef50_Q1IM54 Cluster: Cytochrome P450; n=1; Acidobacteria
           bacterium Ellin345|Rep: Cytochrome P450 - Acidobacteria
           bacterium (strain Ellin345)
          Length = 460

 Score =  123 bits (297), Expect = 1e-26
 Identities = 62/206 (30%), Positives = 120/206 (58%), Gaps = 5/206 (2%)

Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404
           E++++QV TI   G++TTA   S+   ++G + +++ +V+ E+D +   + R  + +D  
Sbjct: 259 EQLRDQVVTIFLAGYETTANALSWTFRLLGENPEVERRVLAEVDDVL--NGRMASVEDVP 316

Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464
           ++KY+E  L E++RLYPP   + RQ   +  L      +P GTT++++ + +HR  + + 
Sbjct: 317 QLKYIEMVLAESMRLYPPAWAMVRQGINDFQL--GDYFLPGGTTVMMSQWVMHRSEEFWL 374

Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDL 524
           +P +FDP+ F PE  A R  +A+ PF  G R C+G  +A ++  ++L+T+++ +R    +
Sbjct: 375 DPLRFDPERFRPEAKAGRPKFAYFPFGGGGRQCIGEAFAWMEGALLLATLVQKYR-FRLV 433

Query: 525 KESDFKLQADIILKRAEGFQVRLQPR 550
               F+ Q+ I L+   G +V  + R
Sbjct: 434 AGQTFEPQSLITLRPRNGVRVVAEAR 459



 Score = 47.6 bits (108), Expect = 9e-04
 Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 1/81 (1%)

Query: 84  DHESVVKIWIGPRLLVFLYDPRDV-EVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKW 142
           D+  V    +G + +VFL D   + EV++  +    K E  R  K  LGNG++ +  Q W
Sbjct: 49  DYGKVGGYRVGNKRVVFLADAELIREVLVVQNDNFVKGEPVRRTKVLLGNGMITAEQQDW 108

Query: 143 RSHRKLIAPTFHLNVLKSFID 163
           RS R+   P FH   ++S+ D
Sbjct: 109 RSQRQAAQPAFHRQRIRSYAD 129


>UniRef50_A7LFI0 Cluster: Cytochrome P450; n=3; Tribolium
           castaneum|Rep: Cytochrome P450 - Tribolium castaneum
           (Red flour beetle)
          Length = 493

 Score =  123 bits (297), Expect = 1e-26
 Identities = 57/177 (32%), Positives = 104/177 (58%), Gaps = 3/177 (1%)

Query: 344 DEEIKEQVDTIMF--EGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           D +IK     I F   G+DTT+   +     + +++ IQD++  E+ +I+ ++    T++
Sbjct: 283 DNDIKMAAQAIAFFSAGNDTTSITLALTCYELSLNKTIQDRLRHEVTEIYNENGE-FTYE 341

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
           + L MKYL+  + ETLR YP  P + R+ + + T    G  +  G ++++    LH  P+
Sbjct: 342 NILGMKYLDMVISETLRKYPLAPFLNRKSDVKYTFEETGFTLDKGVSIMVPISGLHYDPE 401

Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518
            YP+P K+DP+ F  E   N   Y ++PF  GPR+C+G+++A+L  KV L++++++F
Sbjct: 402 YYPDPEKYDPERFSDENKKNLTPYTYLPFGEGPRNCIGQRFALLVSKVALASVVKDF 458


>UniRef50_Q0LL77 Cluster: Cytochrome P450; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Cytochrome P450 -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 446

 Score =  123 bits (296), Expect = 1e-26
 Identities = 63/195 (32%), Positives = 111/195 (56%), Gaps = 6/195 (3%)

Query: 329 LDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           L +LL++     G  ++D ++++++ T+   GH+TTA   ++   ++  H  I  K+ +E
Sbjct: 228 LSVLLQAHDDDDGSFMTDTQVRDELMTLFLAGHETTANALTWTWYLLAHHPHIATKIKDE 287

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           +D   G   R  T  D  ++ Y  +   E+LRLYPPV +IAR+ +Q   L S    +P G
Sbjct: 288 VDSTVGT--RLPTMDDLSKLPYTLQVFKESLRLYPPVYMIARKASQAFELGSY--HVPEG 343

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
              V++ Y +HRR D + +P  F+PD F     A+    A++PFS GPR+C+G  +AM++
Sbjct: 344 MAFVVSPYTIHRRADYFDHPEDFNPDRFDTSHEASIPKNAYIPFSLGPRNCIGNHFAMME 403

Query: 507 LKVILSTILRNFRVI 521
             ++L+ I +  R++
Sbjct: 404 GHLMLAIIAQRMRLL 418



 Score = 42.3 bits (95), Expect = 0.032
 Identities = 30/127 (23%), Positives = 55/127 (43%), Gaps = 3/127 (2%)

Query: 85  HESVVKIWIGPRLLVFLYDPRDVEVILSSHVY-IDKAEEYR-FFKPWLGNGLLISTGQKW 142
           H  +   ++G   +VF+        IL  H   ++K+   R + +P LGNGLL S     
Sbjct: 37  HGDLGVFYLGSYPVVFINSAEYAHGILVQHAQSVEKSLMLRKYMRPLLGNGLLTSENSFH 96

Query: 143 RSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAM 202
           R  RKL+AP F    + ++ +  +A +     +   +    D    M   T+ ++ +T  
Sbjct: 97  RRQRKLVAPAFQHRHIANYANTISAYTDETQARW-HQGQRIDIAQEMMRLTLRVMSQTLF 155

Query: 203 GVSKSTQ 209
               +T+
Sbjct: 156 STDINTE 162


>UniRef50_A7SRX7 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 472

 Score =  123 bits (296), Expect = 1e-26
 Identities = 58/199 (29%), Positives = 110/199 (55%), Gaps = 5/199 (2%)

Query: 323 KKRLAFLDLLLESS---QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           K+    LDL+L ++    +   +SD E+  Q    +  G++TT    SF    +  + D+
Sbjct: 274 KEAKDMLDLMLSAAANENTSKKLSDMEVLAQSLIFLIAGYETTNITLSFVAYSLATNPDV 333

Query: 380 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 439
           Q+K+  E+D ++ + D+  ++     + YL+  + ETLRLYPP  + +R+  Q+  +   
Sbjct: 334 QEKLQREIDSVWTEEDQMPSYDTVHNLPYLDMVISETLRLYPPGFVASRECTQDCVI--K 391

Query: 440 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 499
           G +   G ++ I  Y +H  P+ + +P +FDP+ F  E   +R  Y+++PF  GP +C+G
Sbjct: 392 GYRFRKGLSIFIDAYSMHHDPEFWTDPERFDPERFSRECKQSRDPYSYLPFGHGPHNCIG 451

Query: 500 RKYAMLKLKVILSTILRNF 518
            ++A +++K+ L  +LR F
Sbjct: 452 MRFAQMEIKLALVRVLRKF 470



 Score = 51.2 bits (117), Expect = 7e-05
 Identities = 43/170 (25%), Positives = 76/170 (44%), Gaps = 7/170 (4%)

Query: 141 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSECTVEIL 197
           KW   R  ++P F  + +K  + L N++   +++KL K A   ++F  H +    T++ +
Sbjct: 134 KWHRIRTSLSPAFSAHKMKLMVPLINSSCDVLINKLTKIADSGTSFFVHKFHQGLTMDTI 193

Query: 198 LETAMGVSKSTQ---DQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKL 254
           L+TA G+    Q   D   F  A   M       +    I+L P   + F  +       
Sbjct: 194 LKTAFGIHSEAQTNYDDPAFTAARKSMSTSPARRVMLFLIFLMPFRKYIFRWFPSLLIGN 253

Query: 255 LDIIHGLTKKVIKRKK-EEFASGKKPSNLNETATTSEPSTGKLTSVEGLS 303
            D I  +T K+I+ KK       K   +L  +A  +E ++ KL+ +E L+
Sbjct: 254 FDDIMKITTKMIEVKKVNPHKEAKDMLDLMLSAAANENTSKKLSDMEVLA 303


>UniRef50_Q964T2 Cluster: Cytochrome P450 9e2; n=2; Blattaria|Rep:
           Cytochrome P450 9e2 - Blattella germanica (German
           cockroach)
          Length = 533

 Score =  122 bits (295), Expect = 2e-26
 Identities = 56/178 (31%), Positives = 97/178 (54%), Gaps = 1/178 (0%)

Query: 344 DEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDT 403
           D+++  Q     F G DT +    F   ++  + D+Q+++ +E+DQ   ++D  +T++  
Sbjct: 321 DDDLTAQAVLFFFAGFDTASTLLCFMSHLLATNPDVQNRLQDEIDQSLEENDGKLTYEAI 380

Query: 404 LEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK-KIPAGTTLVIATYKLHRRPDV 462
             MKYL+  + E+LRLYPP     R+  +   LP      +  G  + I  Y +H  P  
Sbjct: 381 HSMKYLDMVVSESLRLYPPAIFTDRKCVKNYRLPMEPSYTLEPGDAVWIPIYAIHHDPKY 440

Query: 463 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520
           YPNP KFDP+ F  E   N   + ++PF +GPR+C+G ++A+++ K+ L  +L  F +
Sbjct: 441 YPNPEKFDPERFSDENKDNIKPFTYLPFGSGPRNCIGNRFALMESKIALVHLLCRFNL 498


>UniRef50_Q9V769 Cluster: Cytochrome P450 6a22; n=2; Sophophora|Rep:
           Cytochrome P450 6a22 - Drosophila melanogaster (Fruit
           fly)
          Length = 499

 Score =  122 bits (295), Expect = 2e-26
 Identities = 74/235 (31%), Positives = 127/235 (54%), Gaps = 8/235 (3%)

Query: 325 RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVI 384
           R  F++LL+E  Q G  ++ EE+  Q       G DT+A+   F L  +     +Q K+ 
Sbjct: 267 RSDFMNLLIEMKQRG-ELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLR 325

Query: 385 EELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK-- 442
           EE+DQ     +   T+    E++Y+E  + ETLR YP +P + R +++ +      +   
Sbjct: 326 EEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTR-ISRHLYAAKGDRHFY 384

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           I  G  L+I  Y +H  P +YP P+KF P+ FL ++ A R   A++PF  GPR+C+G ++
Sbjct: 385 IEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRF 444

Query: 503 AMLKLKVILSTILRNFRVISDLKESDFK---LQADIILKRAEGFQVRLQPRKRMA 554
             ++  + L ++LRNF   S    +D K   L+++I+L  A G  +++Q   +M+
Sbjct: 445 GKMQTTIGLVSLLRNFH-FSVCPRTDPKIEFLKSNILLCPANGIYLKVQQLSQMS 498


>UniRef50_Q825N1 Cluster: Cytochrome P450 hydroxylase; n=6;
           Actinomycetales|Rep: Cytochrome P450 hydroxylase -
           Streptomyces avermitilis
          Length = 504

 Score =  122 bits (294), Expect = 3e-26
 Identities = 68/226 (30%), Positives = 125/226 (55%), Gaps = 9/226 (3%)

Query: 329 LDLLLESSQSGVA--ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           LD +L++++ G    ++ E I+ QV T +  GH+TT+   SF L  +  H D+  +   E
Sbjct: 257 LDRMLDTARPGTGERLAPENIRRQVITFLVAGHETTSGALSFALHYLSRHPDVAARARAE 316

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           +D+++G + RP  +    +++Y+ R L E+LRL+P  P  AR+  ++  L      +  G
Sbjct: 317 VDRVWGGTARP-GYDQVAKLRYVRRVLDESLRLWPTAPAFAREARRDTVL-GGVHPMREG 374

Query: 447 TTLVIATYKLHRRPDVY-PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505
              ++ T  LHR P V+  +  +FDPD F  +   +R  + F PF  G R+C+GR++A+ 
Sbjct: 375 AWALVLTAMLHRDPGVWGADAERFDPDRFDAQAVRSRAAHTFKPFGTGARACIGRQFALH 434

Query: 506 KLKVILSTILRNFRVISDLKESDFKLQ-ADIILKRAEGFQVRLQPR 550
           +  ++L  +LR + + +   E  ++L+ A+ +    EG ++RL  R
Sbjct: 435 EATLVLGLLLRRYELRA---EPGYRLRVAERLTLMPEGLRLRLDRR 477


>UniRef50_Q0LFI0 Cluster: Cytochrome P450; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Cytochrome P450 -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 457

 Score =  122 bits (294), Expect = 3e-26
 Identities = 64/193 (33%), Positives = 110/193 (56%), Gaps = 7/193 (3%)

Query: 329 LDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           LD+LLE+  +++G  +SDE+I+++V TI   GH+TTA   +F   ++  H +I+  +  E
Sbjct: 238 LDMLLEAQDAETGERMSDEQIRDEVLTIFAAGHETTANTLTFGWYLLSEHCEIRQNLQTE 297

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIA-RQVNQEITLPSNGKKIPA 445
           LDQ+     R  +  D  ++ Y  +   E +RLYP  PI   R+V +   L   G  +P 
Sbjct: 298 LDQVL--QGRAPSVNDLPQLPYTLQVFKEAMRLYPAAPITGPRRVTKPTQL--GGYDLPL 353

Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505
            + ++++   LH  P  + NP +FDP  F P  +  RH+ AF+PF AGPR C+G   A +
Sbjct: 354 NSQVIVSITNLHLHPAFWENPLQFDPSRFAPNANQPRHHLAFMPFGAGPRKCIGNNLAEM 413

Query: 506 KLKVILSTILRNF 518
           +  ++L+ + +++
Sbjct: 414 EGALLLACVAQHY 426


>UniRef50_A7T1A2 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 523

 Score =  122 bits (294), Expect = 3e-26
 Identities = 62/199 (31%), Positives = 109/199 (54%), Gaps = 4/199 (2%)

Query: 325 RLAFLDLLLES--SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDK 382
           R  F+DL+L +        +SD EI  Q  T +  GH+T++   S     + ++ ++Q++
Sbjct: 297 RKDFVDLMLSAVNPDGSRKLSDPEIIAQSVTFLLAGHETSSNTLSATAYYLALNPEVQER 356

Query: 383 VIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           +  E+      +      +   +++YL+  + E LR++PP   I R+  Q   +  NG  
Sbjct: 357 LRLEIRMAAETNSEKSPQELANDLEYLDCVVNEVLRIHPPAHTINRECAQACVI--NGIT 414

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKY 502
           IPAG  + I  Y LH  PD +P P+KFDP+ F      +RH + F+PF AGPR+C+G ++
Sbjct: 415 IPAGMDVTIPIYSLHHDPDAWPEPDKFDPERFRGPAKESRHPFQFIPFGAGPRNCIGMRF 474

Query: 503 AMLKLKVILSTILRNFRVI 521
           A+ ++K++L  IL  ++ +
Sbjct: 475 ALNEVKLVLFQILSKYKFV 493


>UniRef50_Q9GQM9 Cluster: Cytochrome P450 6l1; n=1; Blattella
           germanica|Rep: Cytochrome P450 6l1 - Blattella germanica
           (German cockroach)
          Length = 503

 Score =  122 bits (294), Expect = 3e-26
 Identities = 53/192 (27%), Positives = 106/192 (55%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           +D L++  +  + +S+ E+  Q       G +TT++  +F +  + +H +IQD++  E+ 
Sbjct: 270 VDSLIQLKKQLIDVSEHEVLGQAMLFFAAGFETTSSAMAFAMYELALHPEIQDRLRTEIQ 329

Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448
           ++       VT++   +M YL+  + E LR YPP+  I R    +  +P     I  GT 
Sbjct: 330 EVTACHGGQVTYEGVKKMSYLDMVVSEVLRKYPPMSFIDRVCLHDYHIPGTDVVIEKGTP 389

Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508
           + ++   LHR    YP+P  F+P+ F  E+ +  H ++++PF  GPR+C+G +  ++ +K
Sbjct: 390 IFVSLLGLHRDSIFYPDPEDFNPERFNKEKKSGVHPFSYIPFGDGPRNCIGLRLGLMSVK 449

Query: 509 VILSTILRNFRV 520
           +++  +L++ RV
Sbjct: 450 LVIIMLLQSLRV 461


>UniRef50_UPI0000D5650B Cluster: PREDICTED: similar to Cytochrome
           P450 6a2 (CYPVIA2) (P450-B1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Cytochrome P450 6a2
           (CYPVIA2) (P450-B1) - Tribolium castaneum
          Length = 485

 Score =  122 bits (293), Expect = 3e-26
 Identities = 60/204 (29%), Positives = 109/204 (53%), Gaps = 4/204 (1%)

Query: 325 RLAFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVI 384
           R  F+ LL+E  +    ++ EEI  Q       G +T++A  +F L  +  +Q++Q+   
Sbjct: 262 RSDFMQLLIEMKKQN-QLTIEEIAAQCFVFFIAGFETSSATLTFALYELAKNQNLQNVA- 319

Query: 385 EELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIP 444
              D+I  +    +T+    ++K+L++ + ETLR YPP+  + RQ  +   +P     I 
Sbjct: 320 --RDEILANCPNEITYDSLADLKFLDQVVDETLRKYPPLLYVTRQCVKNYKIPDEDVVIE 377

Query: 445 AGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAM 504
            GT + I    LH   + YP P  F+P+ F     + RH Y F+PF  GPR C+G+++ +
Sbjct: 378 KGTLVAIPISALHSDEEFYPKPETFEPERFSKTEKSLRHPYTFLPFGEGPRMCIGKRFGL 437

Query: 505 LKLKVILSTILRNFRVISDLKESD 528
           L++K+ L+ +L+N++   + K  +
Sbjct: 438 LEVKLALTCLLKNYKFSVNCKTKE 461


>UniRef50_UPI00015B4FBC Cluster: PREDICTED: similar to cytochrome
           P450 monooxygenase; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to cytochrome P450 monooxygenase -
           Nasonia vitripennis
          Length = 568

 Score =  121 bits (292), Expect = 4e-26
 Identities = 62/202 (30%), Positives = 107/202 (52%), Gaps = 5/202 (2%)

Query: 324 KRLAFLDLLLE-----SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378
           +R  F+DLL++     S    + ++D  I  Q       G +T++   S  L  + ++  
Sbjct: 335 RRNDFVDLLMDIKDDPSKVGDIEMTDALITAQAFVFFIAGFETSSTTISNALYELALNPS 394

Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438
           +Q+K+ EE+ +   + +  + ++    MKYL +   ETLR YPPV ++ R+  Q  T   
Sbjct: 395 VQEKLREEIIEELANDNGSLKYETIKGMKYLHKVFCETLRKYPPVTVMMRKSMQPYTFSG 454

Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
               IP G  + I  Y + R P +YP+P+ FDP+ F  E    RH   ++PF  GPR+C+
Sbjct: 455 TKVTIPKGMRVWIPAYAIQRDPAIYPDPDTFDPERFSEESIKQRHPSFYLPFGDGPRNCI 514

Query: 499 GRKYAMLKLKVILSTILRNFRV 520
           G ++A  + K+ +  +LRN++V
Sbjct: 515 GARFANYQSKIGIIQVLRNYKV 536


>UniRef50_Q0LJ67 Cluster: Cytochrome P450; n=2; cellular
           organisms|Rep: Cytochrome P450 - Herpetosiphon
           aurantiacus ATCC 23779
          Length = 1053

 Score =  121 bits (292), Expect = 4e-26
 Identities = 72/230 (31%), Positives = 118/230 (51%), Gaps = 8/230 (3%)

Query: 329 LDLLLESSQS--GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           L L+L +  S  G  + D  I+ Q+ T +  GH+TT+   SF    +    +I  +    
Sbjct: 241 LGLMLNAKDSITGEGLDDANIRNQLVTFLIAGHETTSGLLSFATYFLLQQPEILQRAQAI 300

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           +DQ+ GD  R   ++D  ++ YL++ L ETLRL+P  P+       +  +   G  I  G
Sbjct: 301 VDQVLGD--RLPRYEDLAKLGYLDQILRETLRLWPTAPVFGVYAKHDTNI--GGFPIKQG 356

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
              +     LHR P V+ NPN+FDPD F PE       +A+ PF  G R+C+GR +AM +
Sbjct: 357 EKFIALLPTLHRDPKVWLNPNQFDPDRFAPEVREQIPEHAWKPFGNGQRACIGRSFAMQE 416

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRMAKA 556
             ++L+ +L+ F  +S  +     ++  + LK  EG  VR + RK + ++
Sbjct: 417 ASLVLAMMLQRFE-LSQPQPYQLHVKETLTLK-PEGLTVRARVRKNIVRS 464


>UniRef50_Q27691 Cluster: Cytochrome P450; n=2; Musca domestica|Rep:
           Cytochrome P450 - Musca domestica (House fly)
          Length = 503

 Score =  121 bits (292), Expect = 4e-26
 Identities = 58/194 (29%), Positives = 109/194 (56%), Gaps = 2/194 (1%)

Query: 328 FLDLLLE--SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIE 385
           F+DLL+E  + +    +S E++          G +T++   +F L  +  + +IQ+K+  
Sbjct: 273 FMDLLMEIRAKEGEEGLSFEQMAALTFDFFLAGFETSSTTMAFTLYELARNPEIQEKLRT 332

Query: 386 ELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 445
           E+  I  DS+  ++++   +M +LE+ + ETLRLYP +  + R  N++  +P +   I  
Sbjct: 333 EILDILKDSNDELSYEALQKMSFLEQSISETLRLYPVLATLVRVANRDYPVPDSQHIIEK 392

Query: 446 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 505
              +VI  + +H  P+ Y NP +F+P+ F  E    RH   ++PF  GPRSC+G ++  +
Sbjct: 393 DIQVVIPVHAIHHDPEYYENPEEFNPNRFAAEECERRHSSTYLPFGDGPRSCIGMRFGKM 452

Query: 506 KLKVILSTILRNFR 519
           + K+ L ++LR++R
Sbjct: 453 QTKIGLVSLLRHYR 466


>UniRef50_P29980 Cluster: Probable cytochrome P450 110; n=2;
           Nostocaceae|Rep: Probable cytochrome P450 110 - Anabaena
           sp. (strain PCC 7120)
          Length = 459

 Score =  121 bits (292), Expect = 4e-26
 Identities = 58/190 (30%), Positives = 118/190 (62%), Gaps = 8/190 (4%)

Query: 331 LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390
           ++    ++G A++DEE+K+++ TI+F GH+TTA   ++    +  + ++Q+K+ +ELD++
Sbjct: 235 MMAARDENGQAMTDEELKDELLTILFAGHETTATTIAWAFYQILKNVNVQEKLQQELDRL 294

Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450
            G +  P+   +  ++ YL     ETLR+YP +P +  ++ +  ++   G ++   TTL+
Sbjct: 295 -GANPNPM---EIAQLPYLTAVSQETLRMYPVLPTLFPRITKS-SINIAGYQLEPDTTLM 349

Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVI 510
            + Y +H R D+YPNP +F P+ F+  + +   Y   +PF  G R C+G   A+L++K++
Sbjct: 350 ASIYLIHYREDLYPNPQQFRPERFIERQYSPSEY---IPFGGGSRRCLGYALALLEIKLV 406

Query: 511 LSTILRNFRV 520
           ++T+L N+++
Sbjct: 407 IATVLSNYQL 416


>UniRef50_Q16F55 Cluster: Cytochrome P450; n=1; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 543

 Score =  121 bits (291), Expect = 6e-26
 Identities = 60/175 (34%), Positives = 96/175 (54%), Gaps = 6/175 (3%)

Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404
           EE+     + +  G +   +  +F L  +  +  IQ ++ +E+     D+D  +T+   +
Sbjct: 340 EELTTACYSFVKHGMEPCTSVMTFCLYELAKNVSIQKRLRDEISHYLEDTDGQLTYDVIM 399

Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464
            M YL++ + ET+R YPPV  I R+ +Q      +   IP GT  VI  Y  H  PD +P
Sbjct: 400 SMNYLDQVVNETMRKYPPVDFIYRRSSQ------SRDNIPQGTLFVIPVYAFHHDPDHFP 453

Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519
            P KFDP+ F  +++  RH Y ++PF AGPR C+G ++ +L +K  L T+LR FR
Sbjct: 454 APEKFDPERFTAKQARTRHPYCYLPFGAGPRECLGARFGLLVVKAGLVTLLRRFR 508


>UniRef50_Q069I9 Cluster: Gossypol-induced cytochrome P450; n=9;
           Ditrysia|Rep: Gossypol-induced cytochrome P450 -
           Helicoverpa armigera (Cotton bollworm) (Heliothis
           armigera)
          Length = 526

 Score =  120 bits (290), Expect = 8e-26
 Identities = 54/179 (30%), Positives = 98/179 (54%), Gaps = 1/179 (0%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           + D+ +  Q       G++T+A   SF L  +  H + Q + I E+D      +  + ++
Sbjct: 302 VDDDLLVAQCFIFFAAGYETSATTLSFTLYELAKHPEAQKRAIAEVDDYLRRHNNELKYE 361

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
              EM ++E C  ETLR YP + ++ R+V ++ T PS G K+  G  + +  Y LH  P+
Sbjct: 362 CLSEMPFVEACFDETLRKYPVLSLLTREVVEDYTFPS-GLKVEKGLRIFLPLYHLHHNPE 420

Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520
            +P+P ++ P+ FLPE       Y ++PF  GPR C+G ++A +++   + T+L+ +R+
Sbjct: 421 FFPDPEEYRPERFLPENKDKIKPYTYMPFGEGPRLCIGMRFAKMQMTAGIITLLKKYRL 479



 Score = 38.3 bits (85), Expect = 0.53
 Identities = 26/126 (20%), Positives = 53/126 (42%), Gaps = 4/126 (3%)

Query: 89  VKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFF--KPWLGNGLLISTGQKWRSHR 146
           V  + G    + + DP  ++++++   Y   + E   +  +      L  ++G KW+  R
Sbjct: 72  VGAYFGTEPALIVQDPEHIKLVMTKDFYFFSSREISEYADRERFTQNLFSTSGNKWKVLR 131

Query: 147 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA--SNFDCHDYMSECTVEILLETAMGV 204
           + + P F    +K+   L    S    D L KEA  +  +    ++  T++ +   A GV
Sbjct: 132 QNLTPVFTSAKMKNMFHLIEKCSHVFEDFLDKEAKSNEVEMRALVARYTMDCIGTCAFGV 191

Query: 205 SKSTQD 210
              T +
Sbjct: 192 ETKTMN 197


>UniRef50_UPI0000DB6FEA Cluster: PREDICTED: similar to Probable
           cytochrome P450 6a14 (CYPVIA14); n=1; Apis
           mellifera|Rep: PREDICTED: similar to Probable cytochrome
           P450 6a14 (CYPVIA14) - Apis mellifera
          Length = 497

 Score =  120 bits (288), Expect = 1e-25
 Identities = 60/192 (31%), Positives = 96/192 (50%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           +D+L +  ++     +  +  Q       G +  +   S  L  +    +IQ+K   E+ 
Sbjct: 271 IDILADIRENPTKSDNLFLTSQAVLFFLAGFENASLTISNALYELAWKPEIQEKARAEIV 330

Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448
            +    D  +T+    EMKYLE C+ ETLR+YP +  ++R+  +  T       IP G  
Sbjct: 331 NVLQKYDGKITYDGLEEMKYLEACIFETLRMYPVLQWLSREAMETYTFTGTKVTIPKGQQ 390

Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508
           + +  Y + R PD+YPNP+ FDP+ F  ++   RH    +PF  GPR C G + A  +LK
Sbjct: 391 VFLPIYAIQRDPDIYPNPDNFDPERFTDDKIKTRHSMTHLPFGDGPRHCSGIRLAKKQLK 450

Query: 509 VILSTILRNFRV 520
           V L T+L  F+V
Sbjct: 451 VGLVTVLSKFKV 462


>UniRef50_UPI0000D577ED Cluster: PREDICTED: similar to Cytochrome
           P450 6g1 (CYPVIG1) (Cyp6-like protein); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Cytochrome P450 6g1
           (CYPVIG1) (Cyp6-like protein) - Tribolium castaneum
          Length = 523

 Score =  119 bits (287), Expect = 2e-25
 Identities = 69/229 (30%), Positives = 115/229 (50%), Gaps = 6/229 (2%)

Query: 323 KKRLAFLDLLLESSQSGVAISDEEIKEQVDTIMF-EGHDTTAAGSSFFLSMMGIHQDIQD 381
           K R   +D+LL+         + +I      + F  G +TT++   F L     + DIQD
Sbjct: 290 KSRNDLIDILLQMKNDNRNFIEGDILVSQALMFFVAGFETTSSTMGFALYEFARNPDIQD 349

Query: 382 KVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK 441
           K+  E+  I  D    + +    EM+YL+ C+ E LR YP VP + R+ N   T+P    
Sbjct: 350 KIRNEIKDI-SDKYGDIKYDSLKEMEYLDMCVKEVLRKYPVVPFLDRKCNTTYTIPDTNV 408

Query: 442 KIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRK 501
            I   T + I +  LH  P  +PN + FDP+ F          +A++PF  GPR+C+G +
Sbjct: 409 TIDKDTPIFIPSLALHYDPQYFPNADIFDPERFSSNNKTGIDSFAYLPFGEGPRNCIGAR 468

Query: 502 YAMLKLKVILSTILRNFRVISDLKESDFKLQAD---IILKRAEGFQVRL 547
           + +L  K+ L  IL+ F V+S  ++S+ K++ +   ++L    G  ++L
Sbjct: 469 FGLLTAKLGLVHILKEF-VVSCNEKSNEKIKFNPKGMVLSALNGINLKL 516


>UniRef50_A7HP72 Cluster: Cytochrome P450; n=1; Parvibaculum
           lavamentivorans DS-1|Rep: Cytochrome P450 - Parvibaculum
           lavamentivorans DS-1
          Length = 470

 Score =  119 bits (287), Expect = 2e-25
 Identities = 65/221 (29%), Positives = 120/221 (54%), Gaps = 4/221 (1%)

Query: 331 LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390
           L++  S++G  ++ ++++++V T +  GH+TTA   S+   ++ +H + Q+++ EE+  +
Sbjct: 251 LMVSQSKAGHEMTLDQVRDEVATFLLAGHETTATTMSWVWYLLTVHPEWQERLYEEVWAV 310

Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450
                R +T  D   +      + E LRLYPPV  + R+  +   L  +   I  G T++
Sbjct: 311 --TEGRRLTIDDVPALVETRAVIEEALRLYPPVANLMRRAIKTTELTPD-ITIERGQTVL 367

Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVI 510
           I+ + LHR    +  P++FDP  FL E +A R  + ++PF  GPR C+G  +A+L+  +I
Sbjct: 368 ISPWLLHRHRFFWREPDRFDPTRFLGEEAATRPRHLYIPFGGGPRICIGASFALLEAVLI 427

Query: 511 LSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           L+T ++  RV   +       QA I+L+     Q  + PR+
Sbjct: 428 LATFMQRARV-KVINADQVMPQARIVLRPNVALQAVVTPRR 467



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 2/105 (1%)

Query: 103 DPRDVEVILSSHV-YIDKAE-EYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKS 160
           DP  +  IL S   +  K + +    KP LGNGLL + G  WR +RKL AP F  + ++ 
Sbjct: 74  DPDAIRRILVSDAEHFPKDDNQLAILKPLLGNGLLTAEGATWRRNRKLAAPIFQHSSVRD 133

Query: 161 FIDLFNANSRAVVDKLKKEASNFDCHDYMSECTVEILLETAMGVS 205
           F  LF   +     +  ++   F     M++ T+EI+ ET +  +
Sbjct: 134 FAPLFVRAAERSARRALEQQGFFPLDREMTKLTLEIIGETVLSAN 178


>UniRef50_A5HG33 Cluster: Cytochrome P450 monooxygenase CYP6AE; n=2;
           Bombyx mori|Rep: Cytochrome P450 monooxygenase CYP6AE -
           Bombyx mori (Silk moth)
          Length = 516

 Score =  119 bits (287), Expect = 2e-25
 Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 3/212 (1%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           ++DE +  Q  +      +T++   S     +  +   Q + IEE+D  F   +  + F 
Sbjct: 303 VTDELLIAQCVSFFGAAFETSSTTLSLTFYELAKNPKYQKRAIEEVDDYFAKHNNEIEFD 362

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
              E  YL  C+ ETLRLYP +  + R+V ++ T P+ G K+  GT + I  Y L R P 
Sbjct: 363 IVSETPYLNACIDETLRLYPSLANLTREVMEDYTFPT-GLKVEKGTRIHIPVYHLQRNPK 421

Query: 462 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 520
            +P PNKFDP  FLPE     + + ++PF  G R C+  ++A +++    +T+L+ + V 
Sbjct: 422 YFPEPNKFDPRRFLPEAKQTIYPFTYMPFGEGHRICIAMRFAKMQMLAGFATLLKKYEVA 481

Query: 521 ISDLKESDFKLQADIILKR-AEGFQVRLQPRK 551
           + D    +  +   II+    E  Q++L  R+
Sbjct: 482 VDDTTPQELTIDPRIIVTTPIENIQLKLIARQ 513


>UniRef50_UPI00015B60BE Cluster: PREDICTED: similar to cytochrome
           P450 CYP6K1; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to cytochrome P450 CYP6K1 - Nasonia vitripennis
          Length = 496

 Score =  119 bits (286), Expect = 2e-25
 Identities = 67/202 (33%), Positives = 110/202 (54%), Gaps = 10/202 (4%)

Query: 323 KKRLAFLDLLLE---SSQSGV-AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 378
           +KR  F+D L++     Q+ V     E +  Q  T  F G ++++  ++F L  +  H +
Sbjct: 269 EKRGDFIDSLIQLKNGEQNPVYKFEGENLLYQSGTF-FSGFESSSTTTAFTLMELAAHPE 327

Query: 379 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 438
           IQ++  +++++     +  +T++   +MKYL++CL E +RL+PPV  I R   Q+ T+P 
Sbjct: 328 IQERARQDIERAI--EEHGMTYEAFNDMKYLDQCLAEGVRLHPPVSTIDRYTRQDYTIPG 385

Query: 439 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 498
               I  GT + I+ Y L   P  +  P+ FDP+ F  +R  +    AF+PF  GPR CV
Sbjct: 386 TDIVIEKGTAIYISLYGLQEDPRFFTRPSVFDPERFADDRKVSD---AFIPFGIGPRMCV 442

Query: 499 GRKYAMLKLKVILSTILRNFRV 520
           G K   L  KV+L+ ILR + V
Sbjct: 443 GMKAGQLHAKVVLAMILREYTV 464


>UniRef50_Q0GBX4 Cluster: Cytochrome P450 CYP3-like member 1; n=1;
           Ciona intestinalis|Rep: Cytochrome P450 CYP3-like member
           1 - Ciona intestinalis (Transparent sea squirt)
          Length = 512

 Score =  119 bits (286), Expect = 2e-25
 Identities = 61/175 (34%), Positives = 101/175 (57%), Gaps = 5/175 (2%)

Query: 346 EIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLE 405
           EI      ++  G+DT+A   +     +  H+D+Q KV EE+D++  +    +T++    
Sbjct: 308 EITSNSVLMVLAGYDTSANALTLLAYNLATHKDVQKKVQEEIDKML-EKYGSLTYEALNS 366

Query: 406 MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPN 465
           MKYL  CL ETLRLYPP+ I +R  N++IT+  NG  +P G  +++  Y + R  +++  
Sbjct: 367 MKYLGMCLNETLRLYPPIAINSRIPNRDITI--NGVFLPKGIQVIVPVYGMSRDEEIWEE 424

Query: 466 PNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520
           P KF P+     RS +     F PF  GPR C+G ++A+LK+K+ ++ IL +F +
Sbjct: 425 PLKFKPERMEDMRSVDP--MIFQPFGGGPRGCIGMRFAVLKIKLAVAKILHDFNL 477



 Score = 34.3 bits (75), Expect = 8.6
 Identities = 38/184 (20%), Positives = 70/184 (38%), Gaps = 10/184 (5%)

Query: 134 LLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYM 189
           +L++ G++W+  R  + P+F    LK  + +        ++ L K   N    F+     
Sbjct: 124 ILMTEGEQWKRIRNTLTPSFSTAKLKEMLSIMEDCCNHAINILDKATQNDQGRFEAKSVF 183

Query: 190 SECTVEILLETAMGVSKSTQD-QSGFE-YAMAVMKMCDILHLRHTKIWLRPDLLFKFTDY 247
            +  ++I    A  V    QD + G E   + ++K      +  + + +   L F F  +
Sbjct: 184 GKLALDITCSAAFSVDTHPQDLKDGQEPKIIKMVKQAFGFEISRSPLVM---LCFMFPAF 240

Query: 248 AKNQTKL-LDIIHGLTKKVIKRKKEEFASGKKPSNLNETATTSEPSTGKLTSVEGLSFGQ 306
            K   KL   II   T        +     +K S +       +       SVE ++ G+
Sbjct: 241 EKVLCKLDYSIIPKDTVSYFANLTKSLIDQRKHSKVKPRVDLMQLMLNDQVSVEDVAKGK 300

Query: 307 SSGL 310
           S GL
Sbjct: 301 SKGL 304


>UniRef50_Q27664 Cluster: Cytochrome P450 6B2; n=46;
           Obtectomera|Rep: Cytochrome P450 6B2 - Helicoverpa
           armigera (Cotton bollworm) (Heliothis armigera)
          Length = 504

 Score =  119 bits (286), Expect = 2e-25
 Identities = 72/240 (30%), Positives = 123/240 (51%), Gaps = 17/240 (7%)

Query: 328 FLDLLLESSQSGVAISDE--------EIKEQV---DTIMF--EGHDTTAAGSSFFLSMMG 374
           F+DL+LE  Q G   S++        EI E V      +F   G++T+A   ++    + 
Sbjct: 263 FMDLILELRQMGEITSNKYGNNMSTLEITESVMCAQAFVFYIAGYETSATTMAYLTYQLA 322

Query: 375 IHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEI 434
           ++ DIQ+K+I E+D+    +   VT+    +MKYL +   ETLR+Y  V  + R+  ++ 
Sbjct: 323 LNPDIQNKLIAEIDEAIKANGGKVTYDTVKDMKYLNKVFDETLRMYSIVEPLQRKAIRDY 382

Query: 435 TLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGP 494
            LP     I   T ++I+   +H  P  Y NP +F+P+ F  E    RH  A++PF  G 
Sbjct: 383 KLPGTDVVIEKDTVVLISPRGIHYDPKYYDNPKQFNPERFFAEEVGKRHPCAYLPFGLGQ 442

Query: 495 RSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD---IILKRAEGFQVRLQPRK 551
           R+C+G ++  L+  + ++ +L  FR +   K +D  LQ +    I+    G ++ + PRK
Sbjct: 443 RNCIGMRFGRLQSLLCITKLLSKFR-LEPSKNTDRNLQVEPYRFIIGPKGGIRLNIVPRK 501



 Score = 47.6 bits (108), Expect = 9e-04
 Identities = 41/136 (30%), Positives = 57/136 (41%), Gaps = 17/136 (12%)

Query: 83  YDHESVVKIW--IGPRLLVFLYDPRDVEVILSSHVYIDKAEEY-----RFFKPWLGNGLL 135
           +  E V+ I+    P LLV     RD+EVI   H+ I   E +      F K  LG  L 
Sbjct: 66  FPEEKVIGIYRMTSPCLLV-----RDLEVI--KHIMIKDFEVFSDRGLEFSKEGLGQNLF 118

Query: 136 ISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSEC 192
            + G  WR+ R    P F    LK+   L N  +   +D + KE      F+ H  +   
Sbjct: 119 HADGDTWRTLRNRFTPIFTSGKLKNMFYLMNEGADNFIDHVSKECEKHQEFEIHTLLQTY 178

Query: 193 TVEILLETAMGVSKST 208
           T+  +   A GVS  T
Sbjct: 179 TMSTISSCAFGVSYDT 194


>UniRef50_UPI0000E48111 Cluster: PREDICTED: similar to cytochrome
           P450 4F6, partial; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to cytochrome P450
           4F6, partial - Strongylocentrotus purpuratus
          Length = 801

 Score =  118 bits (285), Expect = 3e-25
 Identities = 60/191 (31%), Positives = 112/191 (58%), Gaps = 4/191 (2%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           LD L+ +  +   ++D E+++++++ +F G DTT++  ++ L ++  H + Q KV EE+D
Sbjct: 457 LDTLMLAKDTEGGLTDREMRDEINSFVFGGIDTTSSALTWLLYLLATHPEYQTKVQEEID 516

Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448
            +F D D  V  +D     +L +C+ E+ R+Y  V    R + + + +  +G  +PAGT 
Sbjct: 517 VLFQDRDPEVCSEDLHRTPFLMKCVKESQRMYSFV-TPGRLLTEPLVV--DGLTVPAGTE 573

Query: 449 LVIATYKLHRRPDVYPNPN-KFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507
           L + TY+LH  PDV+ + +  F P+ F  +    R  +AF+PFSAG R+C+ +++A+ ++
Sbjct: 574 LTLFTYQLHHNPDVWGDDHMTFRPNRFDRQNVEGRDPFAFIPFSAGARNCIAQQFALQEI 633

Query: 508 KVILSTILRNF 518
           +V    I   F
Sbjct: 634 QVAAIRIFDKF 644



 Score = 92.3 bits (219), Expect = 3e-17
 Identities = 61/220 (27%), Positives = 104/220 (47%), Gaps = 15/220 (6%)

Query: 92  WIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAP 151
           W G + +V L  P  V  +L+  V   K+E YR F  WLG  +  + G  W+ HR+LI  
Sbjct: 259 WAGWKPIVVLNHPESVRNVLNGSVGTVKSEVYRLFDEWLGQPMATTDGNLWKRHRRLITN 318

Query: 152 TFHLNVLKSFIDLFNANSRAVVDKLKKE---ASNFDCHDYMSECTVEILLETAMGVSKST 208
           +FH NVLKS I   N  +  ++  + +        + H   S  + +++L+ A       
Sbjct: 319 SFHFNVLKSHIPKMNQIADTLISVISQRGVAGELLELHKTTSAFSSDVILQCAFSYESGC 378

Query: 209 QDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKKVIKR 268
           Q+    EY  +V  +  I+  R     L  D +F+ +   K+  K +D++H L +K+I  
Sbjct: 379 QEGVS-EYMKSVSTLAGIVMKRSLSPHLTYDFIFRRSSLYKSWRKEIDVLHRLQEKLISD 437

Query: 269 KKE--------EFASGKKPSNLNETATTSEPSTGKLTSVE 300
           ++E        EF+ GK   ++ +T   ++ + G LT  E
Sbjct: 438 RREQHRQTGCTEFSKGK---DILDTLMLAKDTEGGLTDRE 474



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 47/157 (29%), Positives = 85/157 (54%), Gaps = 5/157 (3%)

Query: 363 AAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPP 422
           +AG+   ++     Q+IQ   I   D+ FG +    + +D     +L +C+ E+ R+Y  
Sbjct: 617 SAGARNCIAQQFALQEIQVAAIRIFDK-FGFTLVRDSTEDLHRTPFLMKCVKESQRMYSF 675

Query: 423 VPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNK-FDPDNFLPERSAN 481
           V    R + + + +  +G  +PAGT L + TY+LH  PDV+ + +  F P  F  +    
Sbjct: 676 VSP-GRLLTEPLVV--DGLTVPAGTELTLFTYQLHHNPDVWGDDHMTFRPSRFDRQNVEG 732

Query: 482 RHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518
           R  +AF+PFSAG R+C+ +++A+ +++V +  I   F
Sbjct: 733 RDPFAFIPFSAGARNCIAQQFALQEIQVAMIRIFDKF 769


>UniRef50_UPI0000E480BF Cluster: PREDICTED: similar to cytochrome
           P450 3A9; n=6; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to cytochrome P450 3A9 -
           Strongylocentrotus purpuratus
          Length = 343

 Score =  118 bits (285), Expect = 3e-25
 Identities = 61/175 (34%), Positives = 96/175 (54%), Gaps = 3/175 (1%)

Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404
           EE+  Q    +  G++TT+A  +    ++  + D QDK+I E+D I    D  V++    
Sbjct: 139 EELLGQAIIFLAAGYETTSALLTLTSYLLATNPDHQDKLIAEIDDIAPKRD-DVSYSTIS 197

Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464
           +M YL++ + E LR+YPP  +  R+  +  T    G KI  G  + I  Y LH  P  +P
Sbjct: 198 KMPYLDQVVCEALRIYPPATLTDRECGETCTY--KGIKIEKGAHIWIPPYTLHHDPHHWP 255

Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519
           NP KFDPD F  E    R+ + ++PF AGPR C+G ++A+++ K+ L   L+  R
Sbjct: 256 NPTKFDPDRFSKENREGRNPFTWIPFGAGPRICIGMRFALMETKMALVRSLQTVR 310


>UniRef50_UPI0000E473D8 Cluster: PREDICTED: hypothetical protein;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 507

 Score =  118 bits (285), Expect = 3e-25
 Identities = 58/176 (32%), Positives = 101/176 (57%), Gaps = 5/176 (2%)

Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404
           E + ++  T+   G +TT+   +F +  +G H D+  K+  E+D++ G     + ++D  
Sbjct: 303 ENMLDEFVTLFIAGQETTSNLLAFTILQLGRHPDVAKKLQAEVDEVLGQK-HTIQYEDLA 361

Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464
           +++Y+ R L ETLRLY PV    R     +    NG  IPA  T+ + +Y + R  + + 
Sbjct: 362 KLEYMMRVLKETLRLYSPVGGTTRLTAHPVKY--NGITIPAKATVTVMSYVMSRMEEYFD 419

Query: 465 NPNKFDPDNFLPERSAN--RHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518
           +P  F+PD F P    +  RH YA+ PFS G RSC+G+++A+++ +VIL+ +L+ F
Sbjct: 420 DPLLFNPDRFKPSEDGSLPRHLYAYFPFSMGQRSCIGQQFALIEARVILAKLLQRF 475



 Score = 42.7 bits (96), Expect = 0.025
 Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 9/149 (6%)

Query: 100 FLYDPRDVEVILSSHVYIDKAEEYRFFKP-----WLGNGLLISTG-QKWRSHRKLIAPTF 153
           F   P  V+ +L +  +I   E Y  F+      ++G+GL+     +KW   R ++ P F
Sbjct: 93  FASAPEIVKELLLNSRHIKPQEIYHGFQKLYGERFMGHGLVSEVDHEKWFHRRAIMNPAF 152

Query: 154 HLNVLKSFIDLFNANSRAVVDKLKKEAS---NFDCHDYMSECTVEILLETAMGVSKSTQD 210
               L S ++ +N+ S A+  KLK++A         D +++ T++++ + A  +  +   
Sbjct: 153 RRKYLISLMEEYNSGSEALCQKLKEKADGKIEVPMLDELNKVTLDVIAKIAFSMDTNAIG 212

Query: 211 QSGFEYAMAVMKMCDILHLRHTKIWLRPD 239
                +  A+      L   H + W   D
Sbjct: 213 DPDCPFPAAITAALQGLQSLHERPWSTMD 241


>UniRef50_A7DLL5 Cluster: Cytochrome P450; n=1; Methylobacterium
           extorquens PA1|Rep: Cytochrome P450 - Methylobacterium
           extorquens PA1
          Length = 466

 Score =  118 bits (285), Expect = 3e-25
 Identities = 60/225 (26%), Positives = 122/225 (54%), Gaps = 6/225 (2%)

Query: 328 FLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 386
           FL  L+ +  + G A+SD +++++V T +  GH+TTA   S+ + ++  H ++   +  E
Sbjct: 241 FLSALMGARDEDGTAMSDRQLRDEVITFLLAGHETTALVLSWTIHLLSRHPEVDRVLATE 300

Query: 387 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAG 446
           + +I     R     D   +++ E  + E++RLYPP   + R+   +  +   G  +  G
Sbjct: 301 IGEIV--VQRAAAIDDVPRLRFAEHTITESMRLYPPAWAVGREARCDCQI--GGFDVRGG 356

Query: 447 TTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLK 506
           T ++I+ + LHR P  +  P  F P+ +    +     +A++PF  GPR C+G ++AM++
Sbjct: 357 TPILISLWVLHRDPRFFDEPEAFRPERWHQGLAQRLPRFAYMPFGGGPRICIGNRFAMIE 416

Query: 507 LKVILSTILRNFRVISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
             +IL+T+++ FR ++D  E    + + + L+   G +V ++ R+
Sbjct: 417 AVLILTTLVQRFRFVADTNEPVVPIPS-MTLRPRGGVRVIIERRE 460



 Score = 44.8 bits (101), Expect = 0.006
 Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 2/78 (2%)

Query: 88  VVKIWIGPRLLVFLYDPRDVE-VILSSHVYIDKAEEY-RFFKPWLGNGLLISTGQKWRSH 145
           VV      +L++ L  PR++E V++  H    K E + R      GNGLL S G  W+  
Sbjct: 54  VVAFRTAGQLMLVLTCPREIERVLVKEHQNFPKNEHFWRQVTALFGNGLLTSKGTFWQRQ 113

Query: 146 RKLIAPTFHLNVLKSFID 163
           R+L AP F   +L S+ D
Sbjct: 114 RRLAAPAFAGPMLASYAD 131


>UniRef50_Q695H1 Cluster: Antennae-rich cytochrome P450; n=3;
           Polyphaga|Rep: Antennae-rich cytochrome P450 -
           Phyllopertha diversa (Pale-brown chafer beetle)
          Length = 507

 Score =  118 bits (285), Expect = 3e-25
 Identities = 57/192 (29%), Positives = 99/192 (51%), Gaps = 1/192 (0%)

Query: 329 LDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELD 388
           + L  E    G       +  Q       G +TT++  S+ L  + +++ IQ+KV+ E+ 
Sbjct: 277 IKLQTEGDFDGYKFEGNRVIAQAAQFFLAGFETTSSTISYALYELCLNKPIQEKVVTEIK 336

Query: 389 QIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTT 448
                    V+++   +MKYL + + E LR YP +P + R+   +  +P     + AGT 
Sbjct: 337 SAL-QQHGSVSYEAIQDMKYLHKVVQEILRKYPVLPFLDRKTTMDWKIPGTNITLEAGTP 395

Query: 449 LVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLK 508
           + I  + LH  P  +PNP+ FDP+ F  E + +R  ++++PF  GPR+C+G ++ ++  K
Sbjct: 396 VYIPMFGLHYDPKYFPNPDVFDPERFTEETTNSRPCFSYIPFGGGPRNCIGERFGLIGTK 455

Query: 509 VILSTILRNFRV 520
           V L  IL  F V
Sbjct: 456 VALVHILSRFEV 467


>UniRef50_A4FHE9 Cluster: Bifunctional P-450:NADPH-P450 reductase 1;
           n=1; Saccharopolyspora erythraea NRRL 2338|Rep:
           Bifunctional P-450:NADPH-P450 reductase 1 -
           Saccharopolyspora erythraea (strain NRRL 23338)
          Length = 1061

 Score =  118 bits (284), Expect = 4e-25
 Identities = 70/215 (32%), Positives = 110/215 (51%), Gaps = 8/215 (3%)

Query: 339 GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPV 398
           G  +    I+ Q+ T +  GH+TT+   SF L  +  +  +   V  E D+++GDS  P 
Sbjct: 246 GTTLDAANIRNQIITFLIAGHETTSGTLSFALHYLAKNPTVLRLVQREADELWGDSPDPE 305

Query: 399 -TFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIP--AGTTLVIATYK 455
            +F+D   + Y  + L ETLRL+P  P   RQ   +  L   G +IP  AG    +    
Sbjct: 306 PSFEDIGRLTYTRQVLNETLRLWPSAPAFGRQARHDTVL---GGRIPMRAGEAAAVLIPM 362

Query: 456 LHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515
           LHR P    NP  FDP  F PE  A R  +AF PF  G R+C+GR++A+ +  ++L+ + 
Sbjct: 363 LHRSPVRGDNPELFDPARFAPEAEAARGPHAFKPFGTGERACIGRQFALDEATMVLAMLA 422

Query: 516 RNFRVISDLKESDFKLQADIILKRAEGFQVRLQPR 550
             +R++ D      K++  + LK  EG  + ++ R
Sbjct: 423 HRYRLV-DHAGYRLKVKETLTLK-PEGLTLAVRAR 455


>UniRef50_Q964R0 Cluster: Cytochrome P450 6k1; n=1; Blattella
           germanica|Rep: Cytochrome P450 6k1 - Blattella germanica
           (German cockroach)
          Length = 524

 Score =  118 bits (284), Expect = 4e-25
 Identities = 55/163 (33%), Positives = 86/163 (52%)

Query: 358 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 417
           G +T A   SF L  + +  D+Q+++  E+  +   S+   T++D   M YL   + ETL
Sbjct: 325 GFETNATTLSFTLYELSLQPDLQNRLRSEIAGVMKTSNGKPTYEDVFGMPYLHMVVSETL 384

Query: 418 RLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPE 477
           R YPP+P++ R   Q+  +P     I   T + IA   LHR P  YPNP ++DP+ F  E
Sbjct: 385 RKYPPLPLLDRVCLQDYKVPGTDLIIERDTPVFIALLGLHRDPQYYPNPERYDPERFSEE 444

Query: 478 RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520
               R  Y ++PF  GP +C+G ++  + +K  L  +L  F V
Sbjct: 445 NKRQRKAYTYLPFGEGPHNCIGLRFGYMAVKTALVHMLAEFEV 487


>UniRef50_UPI0000D561ED Cluster: PREDICTED: similar to Probable
           cytochrome P450 6a16 (CYPVIA16); n=2; Tribolium
           castaneum|Rep: PREDICTED: similar to Probable cytochrome
           P450 6a16 (CYPVIA16) - Tribolium castaneum
          Length = 502

 Score =  118 bits (283), Expect = 5e-25
 Identities = 61/198 (30%), Positives = 105/198 (53%), Gaps = 3/198 (1%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           FL +L++  +S   +S +EI  Q       G  T+A    + +  +   QD+QDKV EE+
Sbjct: 279 FLHMLMQLRESA-GMSLKEIVSQSFLFFIAGFKTSALTMCYCIHELAHSQDLQDKVREEI 337

Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447
            +  G       +++ + +  L++ + ET+R YPP+P++ R   +   +P     I   T
Sbjct: 338 HKNLGRDVSKYAYEELIALPTLDKVVKETMRKYPPLPMLNRICVKSYQVPGTDVVIDKDT 397

Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507
            ++I    L R P+ YP P KFDP+ F      N   Y ++PF  GPR+C+G ++ M+K 
Sbjct: 398 PVIIPVLGLQRDPEFYPEPLKFDPERF--SNDNNIVPYTYLPFGDGPRNCIGLRFGMVKT 455

Query: 508 KVILSTILRNFRVISDLK 525
           K+ ++ +L NFR ++  K
Sbjct: 456 KLAVAALLNNFRFLASSK 473



 Score = 34.7 bits (76), Expect = 6.5
 Identities = 30/150 (20%), Positives = 67/150 (44%), Gaps = 8/150 (5%)

Query: 79  KSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSS--HVYIDKAEEYRFFKPWLGNGLLI 136
           K+  Y H  +   + GP  + F  DP  V+ +L +    ++D+       +  L   +  
Sbjct: 75  KAKGYKHAGIY-FFNGP--IYFPIDPDLVKRVLVTDFEYFVDRGMYGNGDELPLSCHIFS 131

Query: 137 STGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVV---DKLKKEASNFDCHDYMSECT 193
             G++W++ R  ++P+F    +KS  ++   N   +V     L +  +  D  D +   T
Sbjct: 132 MKGEEWKNIRTKMSPSFTAGKMKSIYNIVVHNCENLVKVFQPLAETRTVIDIKDILMRFT 191

Query: 194 VEILLETAMGVSKSTQDQSGFEYAMAVMKM 223
            +++  T+ G+  ++ D    E++  V ++
Sbjct: 192 ADVIGSTSFGIDCNSLDHPDTEFSRMVNRI 221


>UniRef50_UPI00015A5D7D Cluster: hypothetical protein LOC100037390;
           n=1; Danio rerio|Rep: hypothetical protein LOC100037390
           - Danio rerio
          Length = 466

 Score =  118 bits (283), Expect = 5e-25
 Identities = 62/179 (34%), Positives = 102/179 (56%), Gaps = 6/179 (3%)

Query: 322 QKKRLAFLDLLLESSQ--SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDI 379
           ++K    +DLLL + Q  S + + D+++K  V+T  + GHDTTA+  S+    + ++QD 
Sbjct: 283 KRKNTDLIDLLLLAKQKYSKIGLYDDKLKIHVNTNQYSGHDTTASALSWIFYNLAMNQDY 342

Query: 380 QDKVIEELDQIFGDSDRPV---TFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 436
           Q++   E+  +  D D      + +D  ++ +   C+ E+LRL+ PV  + R  +Q +  
Sbjct: 343 QERCRAEVRDLLADRDTHTIGWSEEDLSQLTFTTMCIKESLRLHSPVLALTRYYSQNMKT 402

Query: 437 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 495
           P +   IP G   +I+ Y +HR P V+P+P  FDP  F P  S +R  +AF+PFSAGPR
Sbjct: 403 PGDCV-IPHGCLCLISIYGVHRNPQVWPDPLVFDPTRFDPHNSDSRSPHAFIPFSAGPR 460



 Score = 84.2 bits (199), Expect = 8e-15
 Identities = 47/197 (23%), Positives = 98/197 (49%), Gaps = 8/197 (4%)

Query: 92  WIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 148
           ++GP   +V L+ P  +  +L++   I   +   Y F KPWLGN LL+ +GQ+W  HR+L
Sbjct: 78  FLGPFYNMVRLFHPDYIRSLLTASASITLKDRIFYGFMKPWLGNCLLLQSGQEWSRHRRL 137

Query: 149 IAPTFHLNVLKSFIDLFNANSRAVVDK----LKKEASNFDCHDYMSECTVEILLETAMGV 204
           + P FH ++LK ++ +FN ++  + D+    L     + D  + +S  T++ LL+     
Sbjct: 138 LTPAFHFDILKKYVHIFNQSTNIMHDEWRRLLASGEHSVDMFEQISSLTLDSLLKCTFSC 197

Query: 205 SKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDLLFKFTDYAKNQTKLLDIIHGLTKK 264
              +Q++   +Y  A++ +  +L  R   +    D L+  +   +   +   ++H  T  
Sbjct: 198 DTHSQEKPR-QYISAILDLSRLLVQRQHYLPYHWDWLYWRSAQGRRFQQACAVVHQFTAD 256

Query: 265 VIKRKKEEFASGKKPSN 281
           +++ ++ +      P +
Sbjct: 257 IVQERRTQLDQQSDPES 273


>UniRef50_Q3EBT7 Cluster: Uncharacterized protein At2g26170.1; n=7;
           core eudicotyledons|Rep: Uncharacterized protein
           At2g26170.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 522

 Score =  118 bits (283), Expect = 5e-25
 Identities = 72/228 (31%), Positives = 124/228 (54%), Gaps = 13/228 (5%)

Query: 328 FLDLLLESSQSGVAISDEEIKEQVDTIMFE----GHDTTAAGSSFFLSMMGIHQDIQDKV 383
           FL L+L++ +S     +    + +  + +E    G  TTA   S  L ++  H D++ ++
Sbjct: 294 FLSLILKARESDPFAKNIFTSDYISAVTYEHLLAGSATTAFTLSSVLYLVSGHLDVEKRL 353

Query: 384 IEELDQIFGDSDRPVTFQDTL-EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK 442
           ++E+D  FG+ D   T  D   +  YL++ + E +R Y   P++AR+  +E+ +   G  
Sbjct: 354 LQEIDG-FGNRDLIPTAHDLQHKFPYLDQVIKEAMRFYMVSPLVARETAKEVEI--GGYL 410

Query: 443 IPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP--ERSANRHYYAFVPFSAGPRSCVGR 500
           +P GT + +A   L + P  +P P KF P+ F P  E   +RH YAF+PF  GPR+CVG+
Sbjct: 411 LPKGTWVWLALGVLAKDPKNFPEPEKFKPERFDPNGEEEKHRHPYAFIPFGIGPRACVGQ 470

Query: 501 KYAMLKLKVILSTILRNFRVISDLKESDFKLQAD--IILKRAEGFQVR 546
           ++A+ ++K+ L  + RN+ +     E +  LQ D  IIL    G ++R
Sbjct: 471 RFALQEIKLTLLHLYRNY-IFRHSLEMEIPLQLDYGIILSFKNGVKLR 517


>UniRef50_Q8T624 Cluster: Cytochrome P450 CYP9L1 protein; n=6;
           Cellia|Rep: Cytochrome P450 CYP9L1 protein - Anopheles
           gambiae (African malaria mosquito)
          Length = 533

 Score =  118 bits (283), Expect = 5e-25
 Identities = 71/216 (32%), Positives = 114/216 (52%), Gaps = 10/216 (4%)

Query: 340 VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVT 399
           V +S+ E+  Q       G DT A   +F L  + +  +IQ ++ EE+ Q+    D    
Sbjct: 316 VKLSENEMIAQCLLFFLAGFDTIATSMTFVLYEVTLAPEIQQRLYEEIQQVSETLDGKAL 375

Query: 400 FQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK-KIPAGTTLVIATYKLH 457
             D L+ M+YL+  + ETLR + P P   R  NQ+ T+P +    IP G T+ I    LH
Sbjct: 376 TYDALQGMRYLDMVVSETLRKWSPSPGTDRMCNQDYTIPGDPDIVIPKGATVFIPIAGLH 435

Query: 458 RRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRN 517
             P  YP+P++FDP+ F  E        A++PF  GPR+C+  ++A++++K I+  IL N
Sbjct: 436 YDPRFYPDPDRFDPERFNDENKHKIPLGAYLPFGIGPRNCIASRFALMEVKAIVYHILLN 495

Query: 518 FRVISDLKESDFKLQADIILKRAEGFQVRLQPRKRM 553
           +    +LK S+   +  + +K A+GF   L+P   M
Sbjct: 496 Y----ELKRSE---RTSVPVKLAKGFS-PLKPENGM 523


>UniRef50_Q16FQ1 Cluster: Cytochrome P450; n=2; Aedes aegypti|Rep:
           Cytochrome P450 - Aedes aegypti (Yellowfever mosquito)
          Length = 505

 Score =  118 bits (283), Expect = 5e-25
 Identities = 64/221 (28%), Positives = 112/221 (50%), Gaps = 5/221 (2%)

Query: 333 LESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFG 392
           +E+S +   ++  E+  Q       G +T+++  SF L  +  + ++Q KV  E+D +  
Sbjct: 288 VETSTNSKKLTIGEVAAQAHVFFLAGFETSSSTMSFCLYELAKNPEVQRKVQSEIDSVTA 347

Query: 393 DSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIA 452
             D  +T+    EM+YLE C+ ETLR YPPVP++ R+  ++  +P +   I  GT +++ 
Sbjct: 348 LHDGKLTYDSINEMRYLECCIDETLRKYPPVPVLNRECTKDYKVPDSDITIEKGTAVILQ 407

Query: 453 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 512
              +H  P  YP+P +F P+ FL      + Y    PF  GPR C+G +   ++ KV L 
Sbjct: 408 ISAMHHDPQYYPDPLRFVPERFLDPDMKGKPY---APFGDGPRICIGLRMGKIQTKVGLC 464

Query: 513 TILRNFRV-ISDLKESDFKLQADIILKR-AEGFQVRLQPRK 551
            +L  F   +   KES+  +  +  L     G  +++  R+
Sbjct: 465 LLLSKFNFELYGHKESELVMSPNNFLNTPVNGINLKVSCRE 505


>UniRef50_UPI00015B62A7 Cluster: PREDICTED: similar to cytochrome
           P450; n=2; Nasonia vitripennis|Rep: PREDICTED: similar
           to cytochrome P450 - Nasonia vitripennis
          Length = 940

 Score =  117 bits (282), Expect = 7e-25
 Identities = 54/175 (30%), Positives = 102/175 (58%), Gaps = 1/175 (0%)

Query: 345 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 404
           EE           G++T+++ +SF L  +  + +IQ+K+  E+D++   S   +T++   
Sbjct: 724 EEAAANAFVFFLGGYETSSSTTSFCLYELAQNPEIQEKLQAEIDEVV-KSPTGLTYESIA 782

Query: 405 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 464
           EM+YL+  L ETLR +P +PI+ R   ++  LP+    I     ++I+   +   P+ YP
Sbjct: 783 EMEYLDMVLSETLRKHPSLPILNRIAKEDYPLPTTDFVIKKDMRIMISLSGIQNNPEYYP 842

Query: 465 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519
           +P KFDP  F  E++  R+ Y  +PF  G R C+G+++A++++K+ L+ +L N++
Sbjct: 843 DPEKFDPLRFTKEKAVARNKYINIPFGDGERMCIGKRFAVMQVKIALAAMLHNYQ 897


>UniRef50_Q70AR8 Cluster: Putative cytochrome P450; n=1;
           Streptomyces peucetius|Rep: Putative cytochrome P450 -
           Streptomyces peucetius
          Length = 484

 Score =  117 bits (282), Expect = 7e-25
 Identities = 58/187 (31%), Positives = 105/187 (56%), Gaps = 4/187 (2%)

Query: 334 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 393
           +  Q+G  +SD++++++V T+   G++TTA    +  S++  H + + KV  E+ ++ GD
Sbjct: 265 QDEQTGERMSDKQLRDEVVTMFLGGYETTALSLVWAFSLLSRHPEAERKVRSEVAEVCGD 324

Query: 394 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIAT 453
             R     D   ++YL     E LRLYP V  ++R   ++  +   G  IPAG+ + I+ 
Sbjct: 325 --REPAASDLPRLRYLRAFYQEVLRLYPSVWTLSRSPLEDDEI--GGYHIPAGSQVFISP 380

Query: 454 YKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILST 513
           Y +HR P  + NP  F P+ F    +     YA++PFS GPR C G   A+L+  ++++ 
Sbjct: 381 YLMHRHPGFWENPEGFRPERFEKSATGGAPLYAYIPFSRGPRLCPGSSVAVLEAPLVIAR 440

Query: 514 ILRNFRV 520
           +L+++R+
Sbjct: 441 MLQDYRL 447


>UniRef50_Q26HX2 Cluster: Cytochrome P450 hydroxylase; n=1;
           Flavobacteria bacterium BBFL7|Rep: Cytochrome P450
           hydroxylase - Flavobacteria bacterium BBFL7
          Length = 449

 Score =  117 bits (282), Expect = 7e-25
 Identities = 59/202 (29%), Positives = 111/202 (54%), Gaps = 7/202 (3%)

Query: 329 LDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 387
           LD+LL S+ + G  + D+++ +++  +   GH+TTA   SF + ++  H +  +K  E++
Sbjct: 235 LDMLLHSTYEDGSYMDDDQLVDEILVLFIAGHETTANALSFAVQLLAHHPETIEKAREDV 294

Query: 388 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 447
            +   D          + M YL++C+ ETLRLYPP  +  R+  +      +   I  G+
Sbjct: 295 SKANLDE---TLMNQLMAMPYLKQCVEETLRLYPPAYVTDREALEADEC--DDIFIEKGS 349

Query: 448 TLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKL 507
             +++ Y++HRR D++ NP  FDP  F P ++ +   + F PF AGPR CVG  +AM+++
Sbjct: 350 IWLVSFYEMHRRKDLWENPESFDPSRFEPSKAKSYREFYF-PFGAGPRMCVGNNFAMMEM 408

Query: 508 KVILSTILRNFRVISDLKESDF 529
            +++  ++  F + +     D+
Sbjct: 409 MLVIRRMVERFEITTVQDHIDY 430



 Score = 44.4 bits (100), Expect = 0.008
 Identities = 30/121 (24%), Positives = 61/121 (50%), Gaps = 5/121 (4%)

Query: 62  ALEFVGGSADIFRNIV--QKSADYDHESVVKIWIGPRLLV-FLYDPRDVEVILSSHV--Y 116
           AL F+  S  I+++ +   +     + +  KI   P L++ F  D +  + IL  +   Y
Sbjct: 9   ALTFLAKSRQIYKDPLPFHRENFEKYGNTFKISPKPGLMIHFTCDEKITQHILQKNQKNY 68

Query: 117 IDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKL 176
              + +      ++G+GLL   G+KWR++RKLI P F+   + +F+   +   +  +D++
Sbjct: 69  HKSSLQTEDLGKYIGHGLLTENGEKWRANRKLIQPAFYKKSINNFMATMDVVVKEELDRI 128

Query: 177 K 177
           +
Sbjct: 129 Q 129


>UniRef50_Q52S21 Cluster: Cytochrome P450; n=3; Plutella
           xylostella|Rep: Cytochrome P450 - Plutella xylostella
           (Diamondback moth)
          Length = 514

 Score =  117 bits (282), Expect = 7e-25
 Identities = 58/181 (32%), Positives = 100/181 (55%), Gaps = 2/181 (1%)

Query: 340 VAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVT 399
           + + DE +  Q       G   +A  S++ L  +  +QDIQ++V+ E+D+ +   D   T
Sbjct: 302 IEVDDELLVSQCVLFFQAGFQPSALTSAYLLYELAKNQDIQERVLAEVDEYWSTRDEVQT 361

Query: 400 FQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 459
              T  + +L +C+ E+LR+YPPV ++ R++ ++ TLP NG  +  G  + I  Y LH  
Sbjct: 362 DCVTA-LPFLAQCMEESLRMYPPVSVLMREIYKDYTLP-NGVHLKKGMMIHIPVYHLHHN 419

Query: 460 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519
           P  +P P  F P+ F  E   +   Y ++PF  GPR C+G ++A L++   L+ +L+ +R
Sbjct: 420 PKYFPEPEVFRPERFSEEGRKSIVPYTYLPFGDGPRMCIGYRFARLEIFSSLAVLLKKYR 479

Query: 520 V 520
           V
Sbjct: 480 V 480


>UniRef50_A0NGH0 Cluster: ENSANGP00000031109; n=7; Culicidae|Rep:
           ENSANGP00000031109 - Anopheles gambiae str. PEST
          Length = 541

 Score =  117 bits (282), Expect = 7e-25
 Identities = 58/216 (26%), Positives = 120/216 (55%), Gaps = 8/216 (3%)

Query: 343 SDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD-RPVTFQ 401
           +++E+  Q       G DT +    F +  +  ++++Q+++ EE+ +I    D +P+T+ 
Sbjct: 324 TEKELVAQCFLFFLAGFDTVSTALGFLMYELMRNREVQERLYEEIAEIDQRLDGKPLTYD 383

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGK---KIPAGTTLVIATYKLHR 458
               M+Y++  + E+LRL+PP P++ R  N++ T         KI  G T+++    LH 
Sbjct: 384 AVQGMRYMDMVVSESLRLWPPAPMVDRYCNRDYTFDDGEGLRFKIEKGVTVMVPVAGLHS 443

Query: 459 RPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518
            P  +P+P +FDP+ F  E     +  A++PF  GPR+C+G ++A++++K I+  +L++F
Sbjct: 444 DPKYFPDPKRFDPERFSEENRHKINPGAYLPFGVGPRNCIGSRFALMEVKSIIYYLLKSF 503

Query: 519 RVISDLKESDFKLQ---ADIILKRAEGFQVRLQPRK 551
                 +++   L+   + ++L   +G  +R +PR+
Sbjct: 504 -TFERCEQTQVPLRLKNSPVVLAAEKGIWIRFKPRE 538



 Score = 37.1 bits (82), Expect = 1.2
 Identities = 16/49 (32%), Positives = 28/49 (57%)

Query: 132 NGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA 180
           N L +  GQKWR  R  ++P F  + ++   +L + + + +V+ L KEA
Sbjct: 124 NSLFMLRGQKWRDMRATLSPAFTGSKMRQMFELMSDSCQGMVEHLLKEA 172


>UniRef50_UPI0000E48D2E Cluster: PREDICTED: similar to MGC64404
           protein; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC64404 protein -
           Strongylocentrotus purpuratus
          Length = 509

 Score =  117 bits (281), Expect = 9e-25
 Identities = 55/181 (30%), Positives = 107/181 (59%), Gaps = 3/181 (1%)

Query: 338 SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRP 397
           +G  I   ++ ++  T    G +TT+   +F L  +G H+D+  ++ +E+D++ G S   
Sbjct: 300 NGEKIETADLIDEFGTFFVAGQETTSNLLAFTLLEIGRHKDVAKRLKDEVDEVLG-SKSI 358

Query: 398 VTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLH 457
           +   D  +++Y+ R   ET+RL PPV   +R++  ++   S G  IP G +++  +Y   
Sbjct: 359 IEHSDLTKLEYMSRVFKETMRLNPPVSGASRELASDVQ--SCGYVIPKGASVLFLSYLTS 416

Query: 458 RRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRN 517
           R  + + +P  F+PD F+P     RH++A+ PF+ G R+C+G++ A+++ KVIL+ +L++
Sbjct: 417 RLEEYFDDPLLFNPDRFIPTDETPRHFFAYFPFAIGQRNCIGQQLALIEAKVILAKLLQS 476

Query: 518 F 518
           F
Sbjct: 477 F 477



 Score = 35.1 bits (77), Expect = 4.9
 Identities = 31/181 (17%), Positives = 74/181 (40%), Gaps = 5/181 (2%)

Query: 125 FFKPWLGNGLLISTG-QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN- 182
           F + +LG GL+     +KW + R L+ P F+   L   +D  + ++  + D L   A + 
Sbjct: 125 FGQRFLGLGLVSQVNHEKWHTRRALLNPAFNRKYLMQMMDHKDESATRLRDHLIPLADDK 184

Query: 183 --FDCHDYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDILHLRHTKIWLRPDL 240
                 D+ +  T++++ +    +  +  + S   +  A+      +        L  D 
Sbjct: 185 TLVRMLDHFNNVTLDVIAKVGFDMDINAVENSDCPFPSAIALALQGMDATFKNPLLMVDP 244

Query: 241 LFKFTDYAKNQTKLLDIIHGLTKKVIKRKKEEFASGKK-PSNLNETATTSEPSTGKLTSV 299
             K   Y ++    + ++  + +  I++++E    G++ P ++      +E   G    +
Sbjct: 245 RSKARQYRRSVRDAVKLVRNIGQDCIEKRREAKKKGEELPKDILTCILQAEDDVGNGEKI 304

Query: 300 E 300
           E
Sbjct: 305 E 305


>UniRef50_UPI0000E46433 Cluster: PREDICTED: similar to Cytochrome
           P450, family 2, subfamily u, polypeptide 1; n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Cytochrome P450, family 2, subfamily u, polypeptide 1 -
           Strongylocentrotus purpuratus
          Length = 487

 Score =  117 bits (281), Expect = 9e-25
 Identities = 73/216 (33%), Positives = 111/216 (51%), Gaps = 10/216 (4%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           +  +E+   V  +M  G DTT+    + + +M  + DIQ KV  E+D + G+  R    Q
Sbjct: 270 LKTKEVWRLVYDLMLAGSDTTSNTLKWAVLVMAYYPDIQKKVHNEIDCVLGE--RSPCLQ 327

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
           D   M Y++  +ME LR+ P +P+    +  E T+   G  IP G  L+   +  H  P+
Sbjct: 328 DKKSMSYIQATIMEVLRVRPVLPLALEHLTSETTV-LRGYTIPKGAILIPNVWSCHHNPE 386

Query: 462 VYPNPNKFDPDNFLPE--RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 519
            + NP  F+P  FL E  +S     +AF+PFS GPR C+G + A  +L +I + I++ F 
Sbjct: 387 YWDNPEVFNPGRFLSEDNQSLGEEPHAFLPFSFGPRKCLGDQLAKNELFLIFAKIMQRFH 446

Query: 520 V---ISDLKES-DFKLQADIILKRAEGFQVRLQPRK 551
           +     D  ES D      +IL R    +VRLQPRK
Sbjct: 447 IDFAPGDRPESFDEGFDKGLIL-RPNNMKVRLQPRK 481


>UniRef50_A1WAC7 Cluster: Cytochrome P450; n=1; Acidovorax sp.
           JS42|Rep: Cytochrome P450 - Acidovorax sp. (strain JS42)
          Length = 437

 Score =  117 bits (281), Expect = 9e-25
 Identities = 72/229 (31%), Positives = 122/229 (53%), Gaps = 9/229 (3%)

Query: 328 FLDLLLESSQ--SGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIE 385
           +L +L+++    SG  + D  + ++V T++  GH+TTA+  ++   ++  H + +  +  
Sbjct: 213 WLSMLMQARDKASGEPMPDRALLDEVMTLIVAGHETTASTLNWTWYLLARHPEAEAALHA 272

Query: 386 ELDQIFGDSDRPVTFQDT--LEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 443
            +         P     T      Y+E+ L E LRLYPPV + +R+  Q+ TL   G  +
Sbjct: 273 AIANAAPTEAAPDQALATPFASADYVEQVLQEALRLYPPVWLFSRRAVQDDTL--GGYHV 330

Query: 444 PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYA 503
           PAGT + I  Y LHR    +  P +F P  F+P+ +A RH +A++PFSAGPR CVG  +A
Sbjct: 331 PAGTDIFICPYLLHRDAAQWERPEEFLPARFMPDAAAGRHRFAYLPFSAGPRFCVGAGFA 390

Query: 504 MLKLKVILSTILRNFR-VISDLKESDFKLQADIILKRAEGFQVRLQPRK 551
           M ++   L+ +   FR V  D + ++ + Q  I L+     ++RL  R+
Sbjct: 391 MAEMATHLTMVAERFRWVPVDAEPAEAEFQ--INLRTRHPLRMRLVSRR 437



 Score = 38.7 bits (86), Expect = 0.40
 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 4/102 (3%)

Query: 101 LYDPRDVE-VILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLK 159
           ++DP D+  V+L++     K       +  LGNGL++S G  W   R++I P F     +
Sbjct: 51  IHDPDDIRRVLLTNRGNYVKGAGLERVRVLLGNGLIVSDGDLWVRQRRMIQPAFQGQATR 110

Query: 160 SFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILL 198
            F  +    +  ++ +    A +    D    +S   +EI+L
Sbjct: 111 GFAPVVRQVNADLLTRWSAHADSGEPIDLTHELSSVALEIVL 152


>UniRef50_Q9ASR3 Cluster: At2g46960/F14M4.21; n=7; core
           eudicotyledons|Rep: At2g46960/F14M4.21 - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 519

 Score =  117 bits (281), Expect = 9e-25
 Identities = 72/211 (34%), Positives = 118/211 (55%), Gaps = 7/211 (3%)

Query: 342 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 401
           +S EEI  +  T  F GH+TT+   ++   ++ +HQD Q+K+ EE+ +  G    P + +
Sbjct: 310 MSIEEIIHECRTFFFGGHETTSNLLAWTTMLLSLHQDWQEKLREEIFKECGKEKTPDS-E 368

Query: 402 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 461
              ++K +   +ME+LRLY PV  +AR+ +  I L     +IP GTT+VI   K+H    
Sbjct: 369 TFSKLKLMNMVIMESLRLYGPVSALAREASVNIKL--GDLEIPKGTTVVIPLLKMHSDKT 426

Query: 462 VY-PNPNKFDPDNFLP--ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 518
           ++  + +KF+P  F     R+AN H  A + FS GPR+C+G+ + M++ K +L+ IL+ F
Sbjct: 427 LWGSDADKFNPMRFANGVSRAAN-HPNALLAFSVGPRACIGQNFVMIEAKTVLTMILQRF 485

Query: 519 RVISDLKESDFKLQADIILKRAEGFQVRLQP 549
           R IS   E       ++ ++   G  V LQP
Sbjct: 486 RFISLCDEYKHTPVDNVTIQPQYGLPVMLQP 516


>UniRef50_Q013N6 Cluster: Cytochrome P450, putative; n=2;
           Ostreococcus|Rep: Cytochrome P450, putative -
           Ostreococcus tauri
          Length = 509

 Score =  117 bits (281), Expect = 9e-25
 Identities = 63/202 (31%), Positives = 116/202 (57%), Gaps = 6/202 (2%)

Query: 344 DEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDT 403
           +E++  ++ T +  GH+T+AA   + +  +  ++D   + + E +++ G + +P      
Sbjct: 305 EEQMCFEIKTFLLAGHETSAAMLVWTIYELVKNEDKMTEAVAEANKVLG-AVKPGNLPTR 363

Query: 404 LEMKYLERC---LMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 460
            E+ +L+ C   L ETLRLY  VP++ R+  ++  L   G KIP GTT++I+   +H R 
Sbjct: 364 DELAHLDYCVSALKETLRLYSVVPVVTRRAVEDDVL--GGCKIPKGTTVIISLQGIHHRE 421

Query: 461 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 520
           D++PN   F+P+ FL  +      YA++PF  GPR+C+G+  A+L+ +V+L+T++R F+ 
Sbjct: 422 DLWPNAMSFEPERFLNGKGDEIGNYAYLPFIQGPRNCLGQYLALLEARVVLATLIRRFKF 481

Query: 521 ISDLKESDFKLQADIILKRAEG 542
            S    +  K    I +  A+G
Sbjct: 482 KSASANNGKKHTKAIPIAPADG 503



 Score = 35.9 bits (79), Expect = 2.8
 Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 90  KIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL---GNGLLISTGQKWRSHR 146
           ++ I  R  V + DP  V+ ++ +++   K +    ++P+L   G GL+ S G+ WR+ R
Sbjct: 85  RVQIFQRHCVVVADPELVKRVMQTNLKNYKKDTEFSYEPFLEILGTGLVTSEGETWRAQR 144

Query: 147 KLIAPTFHLNVLKSFI 162
           + I+    + +L   I
Sbjct: 145 QRISSALRIEILDDII 160


>UniRef50_Q8MTC8 Cluster: Cytochrome P450 monooxygenase CYP321A1;
           n=1; Helicoverpa zea|Rep: Cytochrome P450 monooxygenase
           CYP321A1 - Heliothis zea (Corn earworm) (Bollworm)
          Length = 499

 Score =  117 bits (281), Expect = 9e-25
 Identities = 57/173 (32%), Positives = 93/173 (53%), Gaps = 3/173 (1%)

Query: 358 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 417
           G +  A G     +++  H +I  KV +E+D+ F   D  +T+    +M+Y+++ L E+L
Sbjct: 304 GVEPAADGIFATFALLSQHPEILQKVHQEIDEYFEKYDGKITYDVVCDMEYVDKVLSESL 363

Query: 418 RLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPE 477
           R++PP+  + RQ   +  LP    K+  GT L    Y++H  P  YP+P  FDP+ F  E
Sbjct: 364 RMFPPIGFLTRQCIHDTVLPVGNVKVAKGTKLFTPIYEIHHDPKYYPDPEVFDPERFFKE 423

Query: 478 RSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFK 530
           R  N   Y  +PF  G R+C+G +Y  L+L   +  +LR+F  +  + ES  K
Sbjct: 424 RRPNDDLY--MPFGMGNRTCIGARYFKLQLLAAIVHVLRSF-TLKPIPESQQK 473


>UniRef50_A5JM35 Cluster: Cytochrome P450 Cyp6AU1; n=1; Bombyx
           mori|Rep: Cytochrome P450 Cyp6AU1 - Bombyx mori (Silk
           moth)
          Length = 496

 Score =  117 bits (281), Expect = 9e-25
 Identities = 64/217 (29%), Positives = 107/217 (49%), Gaps = 2/217 (0%)

Query: 336 SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD 395
           S+  V I++  +  QV      G+       +F L  +   Q IQ++++ E++ +  + +
Sbjct: 279 SEDFVEITEHVMAGQVFVFFAAGYVNNTITLTFSLYHLAKDQSIQERLMREIETVLENHN 338

Query: 396 RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYK 455
             +T +   EM YLE   +ETLR++P    + R   ++ T+P    +I  GT ++I    
Sbjct: 339 NVLTLEAINEMSYLEMIFLETLRMHPTTNTLQRSALEDYTIPGTDIEIEKGTLVLIPPLA 398

Query: 456 LHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 515
            H    +YP P KFDP+ F  E   +RH  AF+ F  GPR+C+G + A L+ KV +   L
Sbjct: 399 FHHDEKIYPEPEKFDPERFSVENHKSRHACAFLSFGIGPRTCIGIRLAKLQYKVCMVKFL 458

Query: 516 RNFRVISDLKESD-FKLQ-ADIILKRAEGFQVRLQPR 550
             +RV    +  D +K+      L+   G  V + PR
Sbjct: 459 TKYRVAPSTRTKDAYKIDPLRTALEPEGGVYVDILPR 495


>UniRef50_Q59990 Cluster: Putative cytochrome P450 120; n=8;
           Cyanobacteria|Rep: Putative cytochrome P450 120 -
           Synechocystis sp. (strain PCC 6803)
          Length = 444

 Score =  117 bits (281), Expect = 9e-25
 Identities = 61/189 (32%), Positives = 107/189 (56%), Gaps = 5/189 (2%)

Query: 331 LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQI 390
           LL     +   +S  E+K+Q+  ++F GH+T  +  S F  ++G H DI+++V +E +++
Sbjct: 228 LLAARDDNNQPLSLPELKDQILLLLFAGHETLTSALSSFCLLLGQHSDIRERVRQEQNKL 287

Query: 391 FGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLV 450
                + +T +   +M YL++ L E LRL PPV    R++ Q+      G   P G  + 
Sbjct: 288 --QLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGGFRELIQDCQF--QGFHFPKGWLVS 343

Query: 451 IATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGPRSCVGRKYAMLKLKV 509
               + H  PD+YP+P KFDP+ F P+ SA  +  +A VPF  G R C+G+++A L++K+
Sbjct: 344 YQISQTHADPDLYPDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRECLGKEFARLEMKL 403

Query: 510 ILSTILRNF 518
             + +++ F
Sbjct: 404 FATRLIQQF 412


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.321    0.136    0.397 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 582,450,494
Number of Sequences: 1657284
Number of extensions: 23560270
Number of successful extensions: 63637
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1558
Number of HSP's successfully gapped in prelim test: 970
Number of HSP's that attempted gapping in prelim test: 57304
Number of HSP's gapped (non-prelim): 3659
length of query: 556
length of database: 575,637,011
effective HSP length: 105
effective length of query: 451
effective length of database: 401,622,191
effective search space: 181131608141
effective search space used: 181131608141
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 75 (34.3 bits)

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