Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001160-TA|BGIBMGA001160-PA|IPR003010|Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase, IPR003694|NAD+
synthase
(697 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q711T7 Cluster: Glutamine-dependent NAD(+) synthetase (... 958 0.0
UniRef50_Q6IA69 Cluster: Glutamine-dependent NAD(+) synthetase (... 950 0.0
UniRef50_A7SR86 Cluster: Predicted protein; n=1; Nematostella ve... 948 0.0
UniRef50_Q4T8N1 Cluster: Chromosome undetermined SCAF7762, whole... 760 0.0
UniRef50_Q8NIZ2 Cluster: Putative uncharacterized protein 5F3.17... 737 0.0
UniRef50_A0DJV9 Cluster: Chromosome undetermined scaffold_53, wh... 675 0.0
UniRef50_A4R5B7 Cluster: Putative uncharacterized protein; n=3; ... 619 e-176
UniRef50_Q9XXK6 Cluster: Putative uncharacterized protein; n=2; ... 613 e-174
UniRef50_Q2UA53 Cluster: Predicted NAD synthase; n=4; Pezizomyco... 554 e-156
UniRef50_Q4P8K8 Cluster: Putative uncharacterized protein; n=1; ... 453 e-126
UniRef50_UPI0000E4A868 Cluster: PREDICTED: similar to glutamine-... 427 e-118
UniRef50_A6R5W3 Cluster: Putative uncharacterized protein; n=1; ... 401 e-110
UniRef50_A1ZXX0 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;... 236 1e-60
UniRef50_Q053K5 Cluster: NAD(+) synthase; n=4; Leptospira|Rep: N... 231 5e-59
UniRef50_A6DFB9 Cluster: Putative glutamine-dependent NAD(+) syn... 214 8e-54
UniRef50_Q8I2P2 Cluster: NAD synthase, putative; n=6; Plasmodium... 167 7e-40
UniRef50_A5K6Y4 Cluster: NAD synthase, putative; n=1; Plasmodium... 153 1e-35
UniRef50_Q11SE1 Cluster: Glutamine-dependent NAD(+) synthetase; ... 130 2e-28
UniRef50_Q7MWR3 Cluster: Glutamine-dependent NAD+ synthetase; n=... 103 2e-20
UniRef50_Q8ABA5 Cluster: Glutamine-dependent NAD+ synthetase; n=... 99 5e-19
UniRef50_Q897Q2 Cluster: NH3-dependent NAD+ synthetase; n=12; Cl... 95 7e-18
UniRef50_A1IW33 Cluster: Putative calmodulin binding protein; n=... 86 3e-15
UniRef50_Q9X0Y0 Cluster: Probable glutamine-dependent NAD(+) syn... 85 5e-15
UniRef50_A5UWQ0 Cluster: NAD+ synthase; n=6; Bacteria|Rep: NAD+ ... 79 3e-13
UniRef50_UPI00015BCCB0 Cluster: UPI00015BCCB0 related cluster; n... 76 4e-12
UniRef50_Q97I71 Cluster: NH(3)-dependent NAD(+) synthase (NadE) ... 73 2e-11
UniRef50_A6Q824 Cluster: Glutamine-dependent NAD+ synthetase; n=... 73 3e-11
UniRef50_A4M962 Cluster: NAD+ synthetase; n=2; Thermotogaceae|Re... 69 6e-10
UniRef50_P0A5L7 Cluster: Glutamine-dependent NAD(+) synthetase (... 68 1e-09
UniRef50_O29262 Cluster: Probable NH(3)-dependent NAD(+) synthet... 62 6e-08
UniRef50_Q9CBZ6 Cluster: Glutamine-dependent NAD(+) synthetase (... 61 1e-07
UniRef50_Q7URG9 Cluster: Glutamine-dependent NAD(+) synthetase; ... 59 3e-07
UniRef50_Q2RL06 Cluster: NAD+ synthetase; n=1; Moorella thermoac... 57 1e-06
UniRef50_O27554 Cluster: Probable NH(3)-dependent NAD(+) synthet... 56 3e-06
UniRef50_A5UME8 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 56 4e-06
UniRef50_Q2AET7 Cluster: NH(3)-dependent NAD(+) synthetase; n=3;... 54 1e-05
UniRef50_Q58747 Cluster: Probable NH(3)-dependent NAD(+) synthet... 54 1e-05
UniRef50_UPI0000E87BBA Cluster: NAD synthetase; n=1; Methylophil... 54 2e-05
UniRef50_Q0W737 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 54 2e-05
UniRef50_Q8EWK9 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 54 2e-05
UniRef50_A7JIQ8 Cluster: NAD synthase; n=11; Francisella tularen... 52 5e-05
UniRef50_A0LDN5 Cluster: NAD+ synthetase; n=1; Magnetococcus sp.... 52 7e-05
UniRef50_A3EVA0 Cluster: NAD synthase; n=4; Bacteria|Rep: NAD sy... 51 9e-05
UniRef50_Q9HUP3 Cluster: NH(3)-dependent NAD(+) synthetase; n=31... 51 9e-05
UniRef50_A5ZW40 Cluster: Putative uncharacterized protein; n=2; ... 50 2e-04
UniRef50_Q12V31 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 50 2e-04
UniRef50_A7IAS7 Cluster: NAD+ synthetase; n=1; Candidatus Methan... 50 3e-04
UniRef50_Q8RC12 Cluster: NAD synthase; n=5; Clostridia|Rep: NAD ... 49 4e-04
UniRef50_Q8REA7 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;... 49 4e-04
UniRef50_Q3SAC7 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 48 0.001
UniRef50_Q65RB5 Cluster: NH(3)-dependent NAD(+) synthetase; n=3;... 47 0.001
UniRef50_Q9F645 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;... 47 0.001
UniRef50_Q84FA9 Cluster: NH3-dependent NAD+ synthetase; n=3; Cys... 47 0.001
UniRef50_A1AWG7 Cluster: NAD+ synthetase; n=2; sulfur-oxidizing ... 47 0.001
UniRef50_Q2FSW6 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 47 0.002
UniRef50_A6EAE3 Cluster: NAD+ synthetase; n=1; Pedobacter sp. BA... 46 0.003
UniRef50_P75216 Cluster: Probable NH(3)-dependent NAD(+) synthet... 46 0.003
UniRef50_Q7VHF9 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 45 0.006
UniRef50_A7I243 Cluster: NAD+ synthetase; n=1; Campylobacter hom... 45 0.008
UniRef50_A6SYJ8 Cluster: NH(3)-dependent NAD(+) synthetase; n=11... 44 0.010
UniRef50_A5IKN7 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.010
UniRef50_Q8PZP6 Cluster: NH(3)-dependent NAD(+) synthetase; n=3;... 44 0.010
UniRef50_UPI0000DAE70E Cluster: hypothetical protein Rgryl_01001... 44 0.014
UniRef50_Q5ZXJ7 Cluster: Glutamine dependent NAD+ synthetase; n=... 44 0.014
UniRef50_A5IZA1 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;... 44 0.014
UniRef50_A1S062 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.014
UniRef50_A1I7L4 Cluster: Nitrilase/cyanide hydratase and apolipo... 44 0.018
UniRef50_Q6F0U4 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;... 43 0.032
UniRef50_A7H731 Cluster: NAD+ synthetase; n=4; Bacteria|Rep: NAD... 43 0.032
UniRef50_Q6L0D1 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;... 43 0.032
UniRef50_Q5F8V6 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;... 42 0.042
UniRef50_Q97WN9 Cluster: NH(3)-dependent NAD(+) synthetase; n=5;... 42 0.056
UniRef50_A0RPV6 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 42 0.074
UniRef50_Q8U4I9 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;... 42 0.074
UniRef50_Q0AX10 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 41 0.098
UniRef50_Q98PU6 Cluster: NH(3)-dependent NAD(+) synthetase; n=5;... 41 0.098
UniRef50_Q73MV7 Cluster: Glutamine-dependent NAD+ synthetase, pu... 41 0.13
UniRef50_Q6MGT5 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 41 0.13
UniRef50_Q30SA2 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;... 41 0.13
UniRef50_A6DBJ9 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 41 0.13
UniRef50_Q9HNM7 Cluster: NH(3)-dependent NAD(+) synthetase; n=5;... 41 0.13
UniRef50_Q9PPB0 Cluster: NH(3)-dependent NAD(+) synthetase; n=13... 41 0.13
UniRef50_A3H5Q2 Cluster: NH(3)-dependent NAD(+) synthetase; n=3;... 40 0.17
UniRef50_Q9PQ30 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 40 0.23
UniRef50_Q4AHT4 Cluster: NAD+ synthase; n=1; Chlorobium phaeobac... 40 0.23
UniRef50_A6C9U7 Cluster: NAD+ synthetase; n=1; Planctomyces mari... 40 0.23
UniRef50_A1W6S4 Cluster: NAD+ synthetase; n=64; Proteobacteria|R... 40 0.23
UniRef50_Q3IUR2 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 40 0.23
UniRef50_Q5SH30 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;... 40 0.30
UniRef50_A3DP41 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 39 0.39
UniRef50_O25096 Cluster: NH(3)-dependent NAD(+) synthetase; n=5;... 39 0.39
UniRef50_Q1UZK0 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;... 39 0.52
UniRef50_Q9RYV5 Cluster: NH(3)-dependent NAD(+) synthetase; n=12... 39 0.52
UniRef50_A0HL74 Cluster: NAD+ synthetase; n=4; Comamonadaceae|Re... 38 0.69
UniRef50_Q8KEX2 Cluster: NH(3)-dependent NAD(+) synthetase; n=15... 38 0.69
UniRef50_Q1MRS6 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 38 0.91
UniRef50_Q8ZPU5 Cluster: NH(3)-dependent NAD(+) synthetase; n=25... 38 0.91
UniRef50_Q2S5I3 Cluster: NAD(+) synthase; n=1; Salinibacter rube... 38 1.2
UniRef50_Q2GJM2 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;... 38 1.2
UniRef50_Q83RG5 Cluster: NH(3)-dependent NAD(+) synthetase; n=61... 38 1.2
UniRef50_Q3A713 Cluster: Predicted amidohydrolase family protein... 37 1.6
UniRef50_A3JH40 Cluster: Carbon-nitrogen hydrolase family protei... 37 1.6
UniRef50_Q39DY3 Cluster: NAD(+) synthase; n=44; Betaproteobacter... 37 2.1
UniRef50_Q8KCC8 Cluster: Carbon-nitrogen hydrolase family protei... 36 2.8
UniRef50_Q2PY75 Cluster: NH(3)-dependent NAD(+) synthetase; n=18... 36 2.8
UniRef50_Q2N5E0 Cluster: Serine proteinase; n=1; Erythrobacter l... 36 3.7
UniRef50_A6CCB9 Cluster: Predicted amidohydrolase; n=1; Planctom... 36 4.9
UniRef50_Q8G5Q1 Cluster: Glutamine-dependent NAD(+) synthetase; ... 35 6.4
UniRef50_A2GI95 Cluster: Putative uncharacterized protein; n=17;... 35 6.4
UniRef50_Q8VAQ8 Cluster: Wsv343; n=5; Shrimp white spot syndrome... 35 8.5
>UniRef50_Q711T7 Cluster: Glutamine-dependent NAD(+) synthetase (EC
6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing])
(NAD(+) synthetase 1) (NH3-dependent NAD(+)
synthetase-like protein); n=40; Eukaryota|Rep:
Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1)
(NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+)
synthetase 1) (NH3-dependent NAD(+) synthetase-like
protein) - Mus musculus (Mouse)
Length = 725
Score = 958 bits (2370), Expect = 0.0
Identities = 443/691 (64%), Positives = 527/691 (76%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHES 60
MGRKVTVA C LNQWALDFEGN RIL+SIQ AK GA YR GPELEICGY C DH+HES
Sbjct: 1 MGRKVTVATCALNQWALDFEGNFQRILKSIQIAKGKGARYRLGPELEICGYGCWDHYHES 60
Query: 61 DTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDD 120
DT LHS QVL LL SP +DI+ DVGMP+ HRNV YNCRV F NRKI+LIRPKM L ++
Sbjct: 61 DTLLHSLQVLAALLDSPVTQDIICDVGMPIMHRNVRYNCRVIFLNRKILLIRPKMALANE 120
Query: 121 GNYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWN 180
GNYRE RWF+ WT+ RQ E++ LPRM+ +T Q TVP GD V++T+DTC+G EICEELW
Sbjct: 121 GNYRELRWFTPWTRSRQTEEYVLPRMLQDLTKQKTVPFGDVVLATQDTCVGSEICEELWT 180
Query: 181 PQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRI 240
P+S HI + LDGVEII+N SGS+ LRKA+ VDLV AT K+GG YL +N +GCDG R+
Sbjct: 181 PRSPHIDMGLDGVEIITNASGSHHVLRKAHTRVDLVTMATSKNGGIYLLANQKGCDGDRL 240
Query: 241 YFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPR 300
Y++GC+ +A+NG I ++G QF L DVEV TAT+DLED+RSY+A+ SR A P+PR
Sbjct: 241 YYDGCAMIAMNGSIFAQGTQFSLDDVEVLTATLDLEDVRSYKAEISSRNLEATRVSPYPR 300
Query: 301 IFVDVSLSDDEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGV 360
+ VD +LS ED+ + P++W Y PEEEISLGPACWLWD+LRRS Q GFFLPLSGGV
Sbjct: 301 VTVDFALSVSEDLLEPVSEPMEWTYHRPEEEISLGPACWLWDFLRRSKQAGFFLPLSGGV 360
Query: 361 DSSSTACIVFSMCTQICEAIKKGESQVLYDVRKIMCQPDYTPSDPMELCNKLLVTCYMAS 420
DS+++ACIV+SMC +C+A+K G QVL DV+ ++ + YTP DP ELC +LL TCYMAS
Sbjct: 361 DSAASACIVYSMCCLVCDAVKSGNQQVLTDVQNLVDESSYTPQDPRELCGRLLTTCYMAS 420
Query: 421 ENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNLA 480
ENSS+ET RA++LA IGSYH + IDTAV A LGIF+ TG LP F + GG R+NLA
Sbjct: 421 ENSSQETHSRATKLAQLIGSYHINLSIDTAVKAVLGIFSLMTGKLPRFSAHGGSSRENLA 480
Query: 481 LQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIG 540
LQN+QARIRMVL+YLFAQL S+NVDE+L GY+TKYDCSSADINPIG
Sbjct: 481 LQNVQARIRMVLAYLFAQLSLWSRGARGSLLVLGSANVDESLLGYLTKYDCSSADINPIG 540
Query: 541 GISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSE 600
GISKTDL++F+ + RF LP L IL AP TAELEPLADGQ++Q DE+DMGMTYAELS
Sbjct: 541 GISKTDLRAFVQFCAERFQLPVLQTILSAPATAELEPLADGQVSQMDEEDMGMTYAELSI 600
Query: 601 FGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYHAE 660
FG LRK K GPYSMF KL++ W D TP +VAEKVK FF Y++NRHKMT LTP+YHAE
Sbjct: 601 FGRLRKVAKAGPYSMFCKLLNMWRDSYTPTQVAEKVKLFFSKYSMNRHKMTTLTPAYHAE 660
Query: 661 TYSPDDNRFDLRPFLYRVHWNWQFKTIDDAV 691
YSPDDNRFDLRPFLY W WQF ID+ V
Sbjct: 661 NYSPDDNRFDLRPFLYNTRWPWQFLCIDNQV 691
>UniRef50_Q6IA69 Cluster: Glutamine-dependent NAD(+) synthetase (EC
6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing])
(NAD(+) synthetase 1); n=28; Eukaryota|Rep:
Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1)
(NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+)
synthetase 1) - Homo sapiens (Human)
Length = 706
Score = 950 bits (2352), Expect = 0.0
Identities = 436/691 (63%), Positives = 530/691 (76%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHES 60
MGRKVTVA C LNQWALDFEGNL RIL+SI+ AK GA YR GPELEICGY C DH++ES
Sbjct: 1 MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYES 60
Query: 61 DTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDD 120
DT LHS+QVL L++SP +DI+ DVGMPV HRNV YNCRV F NRKI+LIRPKM L ++
Sbjct: 61 DTLLHSFQVLAALVESPVTQDIICDVGMPVMHRNVRYNCRVIFLNRKILLIRPKMALANE 120
Query: 121 GNYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWN 180
GNYRE RWF+ W++ R E+++LPRMI +T Q TVP GDAV+ T DTCIG EICEELW
Sbjct: 121 GNYRELRWFTPWSRSRHTEEYFLPRMIQDLTKQETVPFGDAVLVTWDTCIGSEICEELWT 180
Query: 181 PQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRI 240
P S HI + LDGVEII+N SGS+ LRKA VDLV T K+GG YL +N +GCDG R+
Sbjct: 181 PHSPHIDMGLDGVEIITNASGSHHVLRKANTRVDLVTMVTSKNGGIYLLANQKGCDGDRL 240
Query: 241 YFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPR 300
Y++GC+ +A+NG + ++G QF L DVEV TAT+DLED+RSYRA+ SR A+ P+PR
Sbjct: 241 YYDGCAMIAMNGSVFAQGSQFSLDDVEVLTATLDLEDVRSYRAEISSRNLAASRASPYPR 300
Query: 301 IFVDVSLSDDEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGV 360
+ VD +LS ED+ + PI+W Y SPEEEISLGPACWLWD+LRRS Q GF LPLSGGV
Sbjct: 301 VKVDFALSCHEDLLAPISEPIEWKYHSPEEEISLGPACWLWDFLRRSQQAGFLLPLSGGV 360
Query: 361 DSSSTACIVFSMCTQICEAIKKGESQVLYDVRKIMCQPDYTPSDPMELCNKLLVTCYMAS 420
DS++TAC+++SMC Q+CEA++ G +VL DVR I+ Q YTP DP +LC ++L TCYMAS
Sbjct: 361 DSAATACLIYSMCCQVCEAVRSGNEEVLADVRTIVNQISYTPQDPRDLCGRILTTCYMAS 420
Query: 421 ENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNLA 480
+NSS+ET RA +LA QIGS+H + ID AV A +GIF+ TG P+F + GG R+NLA
Sbjct: 421 KNSSQETCTRARELAQQIGSHHISLNIDPAVKAVMGIFSLVTGKSPLFAAHGGSSRENLA 480
Query: 481 LQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIG 540
LQN+QARIRMVL+YLFAQL S+NVDE+L GY+TKYDCSSADINPIG
Sbjct: 481 LQNVQARIRMVLAYLFAQLSLWSRGVHGGLLVLGSANVDESLLGYLTKYDCSSADINPIG 540
Query: 541 GISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSE 600
GISKTDL++F+ + RF LP+L IL AP TAELEPLADGQ++QTDE+DMGMTYAELS
Sbjct: 541 GISKTDLRAFVQFCIQRFQLPALQSILLAPATAELEPLADGQVSQTDEEDMGMTYAELSV 600
Query: 601 FGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYHAE 660
+G LRK K GPYSMF KL+ W CTP++VA+KVK FF Y++NRHKMT LTP+YHAE
Sbjct: 601 YGKLRKVAKMGPYSMFCKLLGMWRHICTPRQVADKVKRFFSKYSMNRHKMTTLTPAYHAE 660
Query: 661 TYSPDDNRFDLRPFLYRVHWNWQFKTIDDAV 691
YSP+DNRFDLRPFLY W WQF+ I++ V
Sbjct: 661 NYSPEDNRFDLRPFLYNTSWPWQFRCIENQV 691
>UniRef50_A7SR86 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 867
Score = 948 bits (2346), Expect = 0.0
Identities = 438/696 (62%), Positives = 540/696 (77%), Gaps = 3/696 (0%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHES 60
MGRKVT+AVCT+NQWALDF+GNL RILQSIQ AK GA YR GPELEICGY C DHF E
Sbjct: 1 MGRKVTLAVCTINQWALDFDGNLKRILQSIQLAKAKGASYRLGPELEICGYGCNDHFFEG 60
Query: 61 DTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDD 120
DT LHS+QVL LL SP +DI+ DVGMP+ H+NV YNCRV F N KI+LIRPK+ LC+
Sbjct: 61 DTILHSFQVLAFLLNSPVTRDIICDVGMPILHKNVRYNCRVIFLNGKILLIRPKIQLCNT 120
Query: 121 GNYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWN 180
GNYRE RWF+ W K +Q E+F+LPRMI+ +T QSTVP GD V+ST DTCIG E+CEEL++
Sbjct: 121 GNYREMRWFTPWRKMKQTEEFFLPRMISDITGQSTVPFGDGVVSTSDTCIGSEVCEELFS 180
Query: 181 PQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRI 240
S HIP++LDGVEI +NGSGS+ ELRK V+LV SAT K+GG Y++SNLRGCDG+R+
Sbjct: 181 LDSTHIPMALDGVEIFTNGSGSHHELRKLDKRVNLVISATEKAGGVYMYSNLRGCDGERV 240
Query: 241 YFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKP--F 298
Y++GCS +AVNG++V++G QF L DVEV TAT+DLED+ SYR N + AA ++P +
Sbjct: 241 YYDGCSFIAVNGKVVAQGAQFALQDVEVVTATVDLEDVHSYRGANMT-FGAAAIHQPTSY 299
Query: 299 PRIFVDVSLSDDEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSG 358
PR+ VD +L+ D+D+ + + I+ HY +PEEEISLGPACWLWDYLRRSGQ GFFLPLSG
Sbjct: 300 PRVKVDYALTHDDDLVVPLSDAIRVHYHTPEEEISLGPACWLWDYLRRSGQAGFFLPLSG 359
Query: 359 GVDSSSTACIVFSMCTQICEAIKKGESQVLYDVRKIMCQPDYTPSDPMELCNKLLVTCYM 418
G+DSSSTACIV SMC +C++++ G++QVL DVR+++ +Y P+DP EL N++ VTCYM
Sbjct: 360 GIDSSSTACIVASMCHLVCQSVRGGDTQVLEDVRRVVRDSEYIPTDPRELANRIFVTCYM 419
Query: 419 ASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQN 478
+ENSS ET++RA+ LA ++GSYH I ID AV+A L IFTA T +P FK GG +N
Sbjct: 420 GTENSSEETRKRAANLADEMGSYHLGITIDAAVSAVLTIFTAMTSKVPKFKVHGGSHTEN 479
Query: 479 LALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINP 538
LALQN+QAR+RM+ +YLFAQL+ SSNVDE LRGY+TKYDCSSADINP
Sbjct: 480 LALQNVQARLRMIFAYLFAQLILWARGMPGGLLVLGSSNVDEGLRGYLTKYDCSSADINP 539
Query: 539 IGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
IGGISKTDL++F+ + ++ SL IL APPTAELEPL+DGQI Q DE DMGMTY EL
Sbjct: 540 IGGISKTDLRAFIFHCVEKYNFSSLITILGAPPTAELEPLSDGQIQQKDEDDMGMTYDEL 599
Query: 599 SEFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYH 658
S +G LRK CGPYSMF KL+ W D+ +VA KVK FF+ Y+INRHKMT LTPSYH
Sbjct: 600 SLYGRLRKISWCGPYSMFTKLLDVWRDELRADQVANKVKFFFQTYSINRHKMTTLTPSYH 659
Query: 659 AETYSPDDNRFDLRPFLYRVHWNWQFKTIDDAVRTI 694
AE+YSPDDNRFDLRPFLY V W+WQF+TIDD ++ +
Sbjct: 660 AESYSPDDNRFDLRPFLYNVRWSWQFRTIDDQLQKL 695
>UniRef50_Q4T8N1 Cluster: Chromosome undetermined SCAF7762, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7762,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 758
Score = 760 bits (1880), Expect = 0.0
Identities = 366/658 (55%), Positives = 462/658 (70%), Gaps = 18/658 (2%)
Query: 50 GYSCEDHFHESDTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKII 109
GY C DHF+ESDT LHS+QVL +LL+SP +DI+ DVG ++ + + AF + +
Sbjct: 104 GYGCADHFYESDTLLHSFQVLKKLLESPVTEDIICDVG--IEELKLGFENDAAFPGMRAV 161
Query: 110 LIRPKMIL---CDDGNYRETRWFSCWTKDR------------QVEDFYLPRMITAVTNQS 154
+ K + + C +VE+F+LPRMI +T Q
Sbjct: 162 ALGTKENIRATLPASGLSVDKQVDCLLDQAMDPNVLGRVWAGKVEEFFLPRMIQEITGQE 221
Query: 155 TVPIGDAVISTRDTCIGFEICEELWNPQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVD 214
TVP GD V+ST+DTCIG EIC ELW+ +S HI +S DGVEI +N S S+ ELRKA + V+
Sbjct: 222 TVPFGDCVLSTKDTCIGTEICAELWSSKSPHIQMSQDGVEIFTNSSASHHELRKADLRVN 281
Query: 215 LVKSATFKSGGAYLFSNLRGCDGQRIYFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATID 274
L+KSAT KSGG YL++N +GCDG R+Y++GC+ VA+NG+IV++G QF + DVEV +AT+D
Sbjct: 282 LIKSATTKSGGIYLYANQKGCDGDRVYYDGCAMVAINGDIVAQGVQFSVSDVEVISATLD 341
Query: 275 LEDIRSYRAKNRSRCHLAASNKPFPRIFVDVSLSDDEDIHLTTNPPIQWHYLSPEEEISL 334
LED+RSYR + + +L KP R+ V+ SLSD +D L + P++W Y +PEEEISL
Sbjct: 342 LEDVRSYRGQV-NHPYLETEPKPCYRVKVNFSLSDGDDACLPVHQPVEWRYHTPEEEISL 400
Query: 335 GPACWLWDYLRRSGQGGFFLPLSGGVDSSSTACIVFSMCTQICEAIKKGESQVLYDVRKI 394
GPACWLWDYLRRS GF LPLSGGVDS+STAC+V S+C +C A++ G SQVL DVR++
Sbjct: 401 GPACWLWDYLRRSATAGFLLPLSGGVDSASTACMVHSLCVLLCRAVEDGNSQVLEDVRRV 460
Query: 395 MCQPDYTPSDPMELCNKLLVTCYMASENSSRETKQRASQLASQIGSYHFPILIDTAVNAA 454
+ Y P P ELC+++ TCYM SENS+ +T++RA LAS++GS H I ID AV
Sbjct: 461 VGDSAYCPKQPRELCSRIFTTCYMGSENSTEDTRKRAKDLASEVGSTHMNINIDLAVKGI 520
Query: 455 LGIFTAATGLLPIFKSKGGCPRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXX 514
LGIF+A TG P F+ GG R+NLALQN+QAR+RMVL+YLFAQL
Sbjct: 521 LGIFSAVTGKWPEFRVNGGSQRENLALQNVQARVRMVLAYLFAQLSLWSRGKPGGLLVLG 580
Query: 515 SSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAE 574
S+NVDE+L GY TKYDCSSADINPIGGISKTDLK+FL Y + F L SL IL APPTAE
Sbjct: 581 SANVDESLTGYFTKYDCSSADINPIGGISKTDLKNFLLYCVDHFQLTSLKGILAAPPTAE 640
Query: 575 LEPLADGQITQTDEQDMGMTYAELSEFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAE 634
LEPL DG+I+QTDE DM MTY+ELS G LRK CGP+SMF KL+H W D +P EVA+
Sbjct: 641 LEPLKDGEISQTDEADMKMTYSELSVMGRLRKISMCGPFSMFCKLIHLWRDLLSPVEVAQ 700
Query: 635 KVKHFFRCYAINRHKMTVLTPSYHAETYSPDDNRFDLRPFLYRVHWNWQFKTIDDAVR 692
KVKHFF Y++NRHKMT LTP+YHAE+YSPDDNRFDLRPFLY W+WQF+ ID+ VR
Sbjct: 701 KVKHFFWMYSVNRHKMTTLTPAYHAESYSPDDNRFDLRPFLYNTRWSWQFRCIDNQVR 758
Score = 83.4 bits (197), Expect = 2e-14
Identities = 44/82 (53%), Positives = 54/82 (65%), Gaps = 4/82 (4%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHES 60
MGRKVT+A C+LNQWALDFEGN+NRIL+SI+ AK GA YR GPELEI Y+ HF
Sbjct: 1 MGRKVTLATCSLNQWALDFEGNMNRILKSIEIAKSQGAKYRLGPELEI-RYNRLVHF--- 56
Query: 61 DTYLHSWQVLVELLKSPTCKDI 82
D + W V + + D+
Sbjct: 57 DPVVSLWTVTLSVQPESLSDDL 78
>UniRef50_Q8NIZ2 Cluster: Putative uncharacterized protein 5F3.170;
n=3; Sordariomycetes|Rep: Putative uncharacterized
protein 5F3.170 - Neurospora crassa
Length = 729
Score = 737 bits (1822), Expect = 0.0
Identities = 372/707 (52%), Positives = 471/707 (66%), Gaps = 21/707 (2%)
Query: 2 GRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESD 61
G VTVA C+LNQW LD+EGNL RI++SI AK+ GA R GPELEICGYS DHFHE D
Sbjct: 3 GHLVTVATCSLNQWVLDWEGNLQRIVESIHLAKKAGARLRVGPELEICGYSSLDHFHELD 62
Query: 62 TYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDG 121
Y HS ++L +LL+ +C DILIDVG+P+ HRN+ YN R N KI+LIRPKM L +DG
Sbjct: 63 VYTHSLEMLRKLLEDESCHDILIDVGLPILHRNIRYNARAILLNGKILLIRPKMWLANDG 122
Query: 122 NYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNP 181
NYRE R F+ W + R+ E F+LP+++ + ++ V GDAVIST +T G E CEEL+ P
Sbjct: 123 NYREMRHFTPWMRPRETELFHLPKILQEIQGETHVLFGDAVISTPETAFGAETCEELFTP 182
Query: 182 QSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIY 241
++ HI ++LDGVEII+N SGS+ L+K V + L+ AT KSGG YL++N +GCDG+R+Y
Sbjct: 183 KAPHIDMALDGVEIITNSSGSHFTLQKLDVRLQLIMEATRKSGGVYLYANQQGCDGERLY 242
Query: 242 FNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPRI 301
F+GC+ + VNG IV++G QF L DVEV TAT+DLE++R+YR+ A SN + RI
Sbjct: 243 FDGCAMIIVNGNIVAQGSQFSLNDVEVVTATVDLEEVRAYRSSISRGLQAATSNAKYQRI 302
Query: 302 FVDVSLS-DDEDIHLTTNP--PIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSG 358
LS +DED + P P Y S EEEI+L C+LWDYLRRSG G+ +PLSG
Sbjct: 303 QTSFELSPEDEDTDIWKKPTLPRPPRYHSVEEEIALCGGCYLWDYLRRSGTAGYLVPLSG 362
Query: 359 GVDSSSTACIVFSMCTQICEAIKKGESQVLYDVRKI--MCQPDYTPSDPMELCNKLLVTC 416
G+DS +TA +VFSMC + +AI+ G QV+ DVR I + P P ELCN++ T
Sbjct: 363 GIDSCATATLVFSMCRIVIQAIEDGNQQVIDDVRCICKYGKEGELPKTPQELCNQVFTTI 422
Query: 417 YMA-SENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCP 475
YM S+ SS ET+ RA +L+ IGSYH + ID A + T P FK GG
Sbjct: 423 YMGMSKQSSAETRGRAKELSDAIGSYHVNLDIDDVYEAQKKLIVQTTNFEPRFKVHGGTV 482
Query: 476 RQNLALQNIQARIRMVLSYLFAQLMXXXXX--XXXXXXXXXSSNVDEALRGYMTKYDCSS 533
++NL LQ +QARIRMV +Y F Q++ S+NV E+LRGY+TKYDCSS
Sbjct: 483 QENLTLQCLQARIRMVTAYEFGQILPTARGRPGGGSLLVLGSANVGESLRGYLTKYDCSS 542
Query: 534 ADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGM 593
ADINPIG I K DLK F+ +A+ +F LP L L A PTAELEP+ + Q+DE DMGM
Sbjct: 543 ADINPIGSIDKADLKRFIAWAEKKFDLPCLHGFLTAVPTAELEPITQ-EYVQSDEADMGM 601
Query: 594 TYAELSEFGTLRKTYKCGPYSMFEKLVHKWS--------DKC---TPKEVAEKVKHFFRC 642
TYAEL+ FG LRK K GPY+MF++LVH WS D+ TP++VAEKVK FF
Sbjct: 602 TYAELTVFGRLRKLNKLGPYAMFQRLVHDWSADREKVEGDEAPFYTPRQVAEKVKRFFHF 661
Query: 643 YAINRHKMTVLTPSYHAETYSPDDNRFDLRPFLYRVHW-NWQFKTID 688
YAINRHKMT LTP+ H YSPDDNRFDLRPFLY W +W FK ID
Sbjct: 662 YAINRHKMTTLTPALHCNDYSPDDNRFDLRPFLYPPFWKSWSFKRID 708
>UniRef50_A0DJV9 Cluster: Chromosome undetermined scaffold_53, whole
genome shotgun sequence; n=3; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_53, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 685
Score = 675 bits (1668), Expect = 0.0
Identities = 337/690 (48%), Positives = 443/690 (64%), Gaps = 20/690 (2%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
+ VCTLNQWA+DF N+ I++SI+ K LYR GPELEICGY CEDHF ESDT H
Sbjct: 6 LGVCTLNQWAMDFTQNVQNIIESIEICKRKQCLYRLGPELEICGYMCEDHFLESDTVTHC 65
Query: 67 WQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYRET 126
W+ L E+L P +I+ D+GMPV H++V YNCRV N+KI L+RPKM L DDGNYRE+
Sbjct: 66 WEALAEIL--PHTANIVCDIGMPVIHKSVFYNCRVILLNKKIHLVRPKMYLADDGNYRES 123
Query: 127 RWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQSRHI 186
R+F+ W+K+ +ED LP +I T Q VPIG A++ T DT IG EICEE+W P
Sbjct: 124 RYFTPWSKE--IEDLELPPIIQIATGQKCVPIGVAILQTHDTEIGIEICEEMWTPIPTSA 181
Query: 187 PLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYFNGCS 246
+LDG EII N SGS+ E+ K +L K T ++G Y F NLRGCDG R+YF+GCS
Sbjct: 182 NQALDGAEIILNSSGSHYEVGKIKERTELFKDITKRNGACYAFCNLRGCDGNRLYFDGCS 241
Query: 247 CVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPRIFVDVS 306
C+ +NG++ ++ F L DVEVTT IDL+++R+ R +SR +A+ K FPR+ +D++
Sbjct: 242 CIVLNGKVFAKSDAFSLKDVEVTTCDIDLQEVRNIRINIKSRSLMASKQKHFPRVKLDIN 301
Query: 307 LSDDEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGVDSSSTA 366
L+ ++ + PIQ+ E EI AC+LWDY+RRSG GF LPLSGG+DSS+TA
Sbjct: 302 LTQQQNYIYYHDIPIQY-----ESEIEDSTACYLWDYMRRSGACGFMLPLSGGLDSSATA 356
Query: 367 CIVFSMCTQICEAIKKGES------QVLYDVRKIMCQPDYTPSDPMELCNKLLVTCYMAS 420
VF M +I + I ++ +VL +RKI+ +TP P E+ NKL T Y+ S
Sbjct: 357 LTVFFMANKIFKTINNVDNDYQTHIKVLQQLRKIVEDDTFTPKSPQEIVNKLFFTVYLGS 416
Query: 421 ENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNLA 480
ENS+++++ R+ LA QIGS H+ I ID A P F S GG ++LA
Sbjct: 417 ENSTQDSRARSKLLAEQIGSRHYEIEIDQVCKACTSCIKPILKKEPQFVSNGGSLSEDLA 476
Query: 481 LQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIG 540
LQNIQAR RM+L+YL AQL SSN+DE++RG+ TKYDCSSADINPIG
Sbjct: 477 LQNIQARSRMILTYLLAQLTPWNNGKKGFLIVLGSSNLDESIRGFFTKYDCSSADINPIG 536
Query: 541 GISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEP-LADGQITQTDEQDMGMTYAELS 599
+SK DL+ L + F ++ ILEA P+ EL P A+G I+ E DM +T+ EL
Sbjct: 537 SLSKNDLRELLLFCYKTFNFSAIQLILEAKPSPELRPQTAEGHIS---ENDMELTFNELE 593
Query: 600 EFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYHA 659
F LRK K GP SMF+KL + WS+ TP++VAEKVK FF YA+NRHK+ +T S+HA
Sbjct: 594 TFAKLRKVQKLGPVSMFKKLRYLWSN-LTPQQVAEKVKKFFMFYALNRHKVVTITASFHA 652
Query: 660 ETYSPDDNRFDLRPFLYRVHWNWQFKTIDD 689
+ +S DDNRFD R FLY W WQFK ID+
Sbjct: 653 QAFSQDDNRFDFRQFLYNWRWPWQFKKIDE 682
>UniRef50_A4R5B7 Cluster: Putative uncharacterized protein; n=3;
Fungi/Metazoa group|Rep: Putative uncharacterized
protein - Magnaporthe grisea (Rice blast fungus)
(Pyricularia grisea)
Length = 1256
Score = 619 bits (1530), Expect = e-176
Identities = 327/679 (48%), Positives = 429/679 (63%), Gaps = 14/679 (2%)
Query: 3 RKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDT 62
R VTVA TL LDFEGN +RIL+SI+ AKE GA RTGPELEI GY C DH E DT
Sbjct: 2 RFVTVAAATLPSVPLDFEGNRDRILESIKLAKEKGATLRTGPELEIPGYGCLDHHLEGDT 61
Query: 63 YLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGN 122
LHSW+VL E++ P CKD+L+D+G+ V+ RNV YNCRV +KI IR K L DG
Sbjct: 62 ELHSWEVLAEIISDPVCKDMLVDLGLGVKTRNVQYNCRVLCTYKKIYAIRAKQALAGDGL 121
Query: 123 YRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQ 182
YRE R F+ W K+RQVE L +++ VT Q+TVPIGD ++ T DT + E CEEL+ P+
Sbjct: 122 YREPRHFTAWVKERQVETHKLHKVVRDVTGQTTVPIGDFILETPDTSVTCETCEELFVPR 181
Query: 183 SRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQ-RIY 241
+ I L+G EII N S S+ ELRK ++L+ ++T +GG Y+++N G DG+ R+
Sbjct: 182 NPSIFSGLNGAEIILNSSASHAELRKLGTRLNLISNSTRSNGGLYVYANASGIDGEARML 241
Query: 242 FNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPRI 301
F+G S + NGE++++ QF L+ VEVT AT+DLE +RSYR + SR AA +PRI
Sbjct: 242 FDGSSMIIQNGEVLAQSSQFSLLPVEVTVATVDLERVRSYRT-SASRNVQAARQPEYPRI 300
Query: 302 FVDVSLSDDEDIHLTTNPPIQW----HYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLS 357
D+ L+ + +N I L P EEI + + +LW YL RS GFFL LS
Sbjct: 301 DCDIELARPSEEIFRSNKVIAMEIPIRILDPMEEIHMATSVYLWQYLVRSSGAGFFLALS 360
Query: 358 GGVDSSSTACIVFSMCTQICEAIKKGESQVLYDVRKIMCQPDYTPSDPMELCNKLLVTCY 417
GG+DSSS A V+ M + +IK GE L D+RK+ DY P P E+ KLL TC+
Sbjct: 361 GGLDSSSVALFVYGMAKLVLLSIKNGEENTLNDLRKVTGINDYVPESPEEIVGKLLHTCF 420
Query: 418 MASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAAT-GLLPIFKSKGGCPR 476
M + NSS ET+ RA +LA ++G+YH I ID AV A I +A G P + +GG
Sbjct: 421 MGTVNSSDETRSRAKRLAERLGAYHTDINIDNAVQAHESIIESALGGFKPKYAVEGGTNS 480
Query: 477 QNLALQNIQARIRMVLSYLFAQLMXXXX---XXXXXXXXXXSSNVDEALRGYMTKYDCSS 533
+NLA QNIQAR R+V+SY AQL S NVDE LRGY TKYD SS
Sbjct: 481 ENLAKQNIQARNRLVVSYELAQLSTQARGLPRAGASLLVLGSGNVDENLRGYYTKYDASS 540
Query: 534 ADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGM 593
AD+ P+G ISK D K F +A++ + L +SE ++A P+AEL PL+ G Q DE +MG+
Sbjct: 541 ADLAPLGSISKNDAKDFQRWARDNWDLSIMSEFIDAIPSAELLPLSAG--VQADEVEMGL 598
Query: 594 TYAELSEFGTLRKTYKCGPYSMFEKLVHKWSDK--CTPKEVAEKVKHFFRCYAINRHKMT 651
TY+ELS+FG LRK K GP+S + +L+ +W ++ P+E+AEKV FFR YAINRHK T
Sbjct: 599 TYSELSDFGILRKVDKLGPWSAYLRLLSQWKERPGFGPREIAEKVFLFFRFYAINRHKAT 658
Query: 652 VLTPSYHAETYSPDDNRFD 670
++TPS H Y+PDDNR D
Sbjct: 659 IITPSVHLSAYNPDDNRHD 677
>UniRef50_Q9XXK6 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 703
Score = 613 bits (1514), Expect = e-174
Identities = 319/695 (45%), Positives = 433/695 (62%), Gaps = 11/695 (1%)
Query: 3 RKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDT 62
R+ VA CT+N WALDF+GN RI+++ +EA LGA R GPELEI GY C DHF E DT
Sbjct: 6 RRCRVATCTVNNWALDFKGNYERIVKTCEEAAALGARIRLGPELEIPGYGCADHFFELDT 65
Query: 63 YLHSWQVLVELL-KSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDG 121
HSW++L +L+ KS ++L+ G+P + R + YNC A N K++ IR KM L DD
Sbjct: 66 ERHSWEMLSKLVEKSKKWPNLLVVTGLPTRFRGLLYNCAAALRNGKLLFIRAKMGLADDN 125
Query: 122 NYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTC-IGFEICEELWN 180
YRE+RWF WT+ + + +P +Q TVP GD ++ + D IGFEICEELW+
Sbjct: 126 VYRESRWFVKWTET--FKHYQMPLNSDIHFDQETVPFGDGILESSDNVRIGFEICEELWS 183
Query: 181 PQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVD-LVKSATFKSGGAYLFSNLRGCDGQR 239
+S ++ L+ GV+I+ NGSGS+ L K+ ++ L+ ++ K GG YL++N RGCDG R
Sbjct: 184 ARSTNVRLAEQGVDIMCNGSGSHHILGKSNYRINQLILGSSAKVGGVYLYANQRGCDGDR 243
Query: 240 IYFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFP 299
+Y++G S VA NG+++++ QF + D V +A +DL D + +R S A+
Sbjct: 244 VYYDGASSVAQNGDLLAQIHQFDIEDTSVVSAVVDLSDNQCFRHMKSSDRGNASDQVTVV 303
Query: 300 RIFVDVSLSDDEDIHLTTNPPI---QWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPL 356
I D ++ + + PI + LSP E+ GP +LW YLRRSG G+F+PL
Sbjct: 304 PIRFDGKMTGGIKYNEKSTAPIHNVEDLQLSPIAELCHGPPAYLWTYLRRSGMAGYFIPL 363
Query: 357 SGGVDSSSTACIVFSMCTQICEAIKKGESQVLYDVRKIMCQPDYTPSDPMELCNKLLVTC 416
SGG DSS+ A +V MC ++C AIK+ D DP ELCN++L TC
Sbjct: 364 SGGQDSSAVAAMVRLMCEKVCGAIKRRRETDGGDDPAYYLGGKKVGEDPAELCNQVLFTC 423
Query: 417 YMASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPR 476
YMASE+SS ET+Q A LA + S H I IDT V + L +F A G +P F+S R
Sbjct: 424 YMASEHSSDETRQCAEGLAKNVNSSHCGIFIDTIVTSILKVFNVAYGFMPSFQSPDN--R 481
Query: 477 QNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADI 536
+ +ALQNIQARIRMVLSYLFAQL ++NVDE+L GY+TKYDCSSADI
Sbjct: 482 ETMALQNIQARIRMVLSYLFAQLALVSHKRPGGLLVLGTANVDESLVGYLTKYDCSSADI 541
Query: 537 NPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYA 596
NPIG +SK DL+ FL A ++ + +L ++++ PTAEL+PL DG++ QTDE ++G+TY
Sbjct: 542 NPIGSVSKRDLRQFLEIAYEKYGMAALRCVIDSTPTAELKPLVDGKVAQTDEAEIGLTYD 601
Query: 597 ELSEFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPS 656
ELS G LRK GPY MF KL+ W DK + E+ EKV FF Y +NRHK TV TP+
Sbjct: 602 ELSVIGRLRKPGGMGPYGMFLKLLQLWGDKYSIDEIEEKVNKFFWRYRVNRHKATVSTPA 661
Query: 657 YHAETYSPDDNRFDLRPFLYRVHWNWQFKTIDDAV 691
HAE YSPDD+R D RPFLY +++QF+ I + V
Sbjct: 662 IHAENYSPDDHRNDHRPFLY-PDFSYQFERIREKV 695
>UniRef50_Q2UA53 Cluster: Predicted NAD synthase; n=4;
Pezizomycotina|Rep: Predicted NAD synthase - Aspergillus
oryzae
Length = 749
Score = 554 bits (1367), Expect = e-156
Identities = 274/525 (52%), Positives = 364/525 (69%), Gaps = 14/525 (2%)
Query: 178 LWNPQSRHIPLSLD-GVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCD 236
+W P + PL+ GVEIISN SGS+ ELRK ++LV AT SGG YL++N +GCD
Sbjct: 209 VW-PSLQDRPLTSPIGVEIISNSSGSHHELRKLDTRINLVTQATKLSGGIYLYANQQGCD 267
Query: 237 GQRIYFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNK 296
G R+Y++GC+ + VNG IV++G QF L DVEV TAT+D+E++R+YR+ + SR A+
Sbjct: 268 GDRLYYDGCAMIVVNGNIVAQGSQFSLNDVEVVTATVDIEEVRTYRS-SASRGMQASKQT 326
Query: 297 PFPRIFVDVSLS---DDEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFF 353
PF R+ +D+ LS ++ D L + I Y +PEEE++LGPACWLWDYLRRSG GFF
Sbjct: 327 PFVRLDLDMRLSRQNEEADPGLAPSEAIAPRYHAPEEEVALGPACWLWDYLRRSGAAGFF 386
Query: 354 LPLSGGVDSSSTACIVFSMCTQICEAIKKGESQVLYDVRKIMCQP---DYTPSDPMELCN 410
LPLSGG+DS +TA IV SMC ++ +A+ +G QV+ DVR++ +P + P+ E+CN
Sbjct: 387 LPLSGGIDSCATAIIVHSMCREVIKAVSEGNEQVIKDVRRLCAEPADSTWLPTTSQEVCN 446
Query: 411 KLLVTCYMASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKS 470
++ T YM ++NSS+ET+ R+ +L++ IGSYH DT V + +FT T P FK
Sbjct: 447 RIFHTSYMGTQNSSKETRDRSKRLSTDIGSYHVDFNFDTVVTSLTNLFTMVTNFQPKFKV 506
Query: 471 KGGCPRQNLALQNIQARIRMVLSYLFAQLMXXXXXX--XXXXXXXXSSNVD-EALRGYMT 527
GG +N ALQN+QAR+RMVLSYLFA L+ SSNVD E LRGY+T
Sbjct: 507 HGGSRAENQALQNVQARLRMVLSYLFASLLPTVRQRPGGGGLLVLASSNVDAECLRGYLT 566
Query: 528 KYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTD 587
KYD SSAD+NPIG ISK DLK F+ ++++ F LP L E L A PTAELEP+ + Q+D
Sbjct: 567 KYDASSADLNPIGSISKVDLKKFIAWSRDSFELPILHEFLNATPTAELEPITSTYV-QSD 625
Query: 588 EQDMGMTYAELSEFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINR 647
E DMG+TYAELS FG LRK K GP+SM+E+L+H W ++ +P+E+ EK +HFF YAINR
Sbjct: 626 EADMGVTYAELSTFGYLRKIAKLGPWSMYERLLHVWGNEYSPREIYEKTRHFFYNYAINR 685
Query: 648 HKMTVLTPSYHAETYSPDDNRFDLRPFLYRVHWNWQFKTIDDAVR 692
HKMTVLTPSYHAE YSPDDNR DLR FLY + W +K ++D+V+
Sbjct: 686 HKMTVLTPSYHAEQYSPDDNRHDLRQFLY-PSFTWAYKKMEDSVK 729
Score = 254 bits (623), Expect = 4e-66
Identities = 111/188 (59%), Positives = 142/188 (75%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHES 60
MG VT+A C+LNQWALDFEGN RI++SI++AK+ GA R GPELEI GY D F E
Sbjct: 1 MGHLVTLATCSLNQWALDFEGNCERIIESIRQAKKAGATLRVGPELEITGYGVLDGFLEG 60
Query: 61 DTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDD 120
DT+LHSW++L ++ C+DI++DVGMPV+HRNV YNCRV F+NRKIILIRPKM L +D
Sbjct: 61 DTFLHSWEMLARIIDHADCQDIVVDVGMPVRHRNVRYNCRVIFYNRKIILIRPKMWLAND 120
Query: 121 GNYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWN 180
GNYRE R+F+ W + +++ED+YL ++ +T Q VP GDAVISTRDTC+G E CEEL+
Sbjct: 121 GNYREMRYFTPWQRPQEIEDYYLESIVGKITGQYKVPFGDAVISTRDTCLGLETCEELFT 180
Query: 181 PQSRHIPL 188
P + L
Sbjct: 181 PNGYALQL 188
>UniRef50_Q4P8K8 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 767
Score = 453 bits (1116), Expect = e-126
Identities = 227/398 (57%), Positives = 276/398 (69%), Gaps = 21/398 (5%)
Query: 320 PIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGVDSSSTACIVFSMCTQICEA 379
PI+ HY SPE+EI+LGPACWLWDYLRRS G+F+PLSGG+DS +TA IVFSMC + A
Sbjct: 356 PIEVHYHSPEQEIALGPACWLWDYLRRSRTQGYFVPLSGGIDSCATATIVFSMCRLVIAA 415
Query: 380 IKKGES-----------------QVLYDVRKIMCQ-PDYT--PSDPMELCNKLLVTCYMA 419
I S QVL DVR+I + P T P+ P ELCN++ VTCYM
Sbjct: 416 IDAPSSSSPASKATSSLTTDTRTQVLQDVRRICNEKPSSTWIPASPQELCNRIFVTCYMG 475
Query: 420 SENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNL 479
+ENSS ET+QRA LA+ IG+YH + +D V A + +F+ TG P F+ GG P +NL
Sbjct: 476 TENSSAETRQRAKDLAADIGAYHIDLNMDIVVRAIIALFSTVTGSTPRFRVHGGTPAENL 535
Query: 480 ALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPI 539
ALQNIQAR+RM+L+Y+FAQL S+NVDE+LRGY+TKYDCSSADINPI
Sbjct: 536 ALQNIQARLRMLLAYMFAQLTPWVRGSWGGLLVLGSANVDESLRGYLTKYDCSSADINPI 595
Query: 540 GGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELS 599
GGISKTDLK+F+ YA++ F LP L L A PTAELEP+ + + Q DE DMGMTY ELS
Sbjct: 596 GGISKTDLKAFIAYARDAFSLPILHSFLTAVPTAELEPITESYV-QADEADMGMTYDELS 654
Query: 600 EFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYHA 659
FG LRK KCGPYSMF KL+ +W P+ VAEKVK F+ YA NRHKMT LTPSYHA
Sbjct: 655 VFGRLRKNLKCGPYSMFNKLLQQWGPTMGPERVAEKVKLFWFEYARNRHKMTTLTPSYHA 714
Query: 660 ETYSPDDNRFDLRPFLYRVHWNWQFKTIDDAVRTIFMF 697
E+YSPDDNRFDLRPFLY + +QF+ ID+ V+ + F
Sbjct: 715 ESYSPDDNRFDLRPFLYPSRFPFQFRKIDELVKRLQAF 752
Score = 371 bits (912), Expect = e-101
Identities = 173/314 (55%), Positives = 226/314 (71%), Gaps = 2/314 (0%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHES 60
MG VTV+ C+LNQWALDF+GN +RIL+SI+ AK +G+ R GPELEI GY C DHF E
Sbjct: 1 MGLPVTVSTCSLNQWALDFDGNRDRILESIRLAKSVGSRLRVGPELEIPGYGCFDHFLEP 60
Query: 61 DTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDD 120
DT LHSWQVL E+L S IL DVGMPV HR+ YNCRV + KI+ IRPKM L +D
Sbjct: 61 DTVLHSWQVLAEILSSDATNGILCDVGMPVLHRSTLYNCRVLLLDGKILHIRPKMWLAND 120
Query: 121 GNYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWN 180
GNYRE R+FS WT+ + F LPR+++++T+Q VP GDAV+ TRDT +G E+CEEL+
Sbjct: 121 GNYREMRYFSPWTRTNHTDSFPLPRIVSSITDQHEVPFGDAVVKTRDTVLGVELCEELFT 180
Query: 181 PQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRI 240
P S HI LDGVEI +N S S+ ELRK Y V+L+K AT K GG YL++N +GCDG R+
Sbjct: 181 PNSPHIRQGLDGVEIFTNSSASHHELRKLYRRVELIKEATLKLGGIYLYANQQGCDGDRL 240
Query: 241 YFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYR-AKNRSRCHLAAS-NKPF 298
Y++GC +AVNG IV++G QF L DV+V +AT+DL+D+R++R AK+R ++ S +
Sbjct: 241 YYDGCPLIAVNGSIVAQGSQFSLDDVQVVSATVDLDDVRAHRSAKSRGMQAVSHSLGSGY 300
Query: 299 PRIFVDVSLSDDED 312
PRI VD + + E+
Sbjct: 301 PRIHVDFEVGESEE 314
>UniRef50_UPI0000E4A868 Cluster: PREDICTED: similar to
glutamine-dependent nad(+) synthetase; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
glutamine-dependent nad(+) synthetase -
Strongylocentrotus purpuratus
Length = 863
Score = 427 bits (1051), Expect = e-118
Identities = 201/308 (65%), Positives = 235/308 (76%)
Query: 381 KKGESQVLYDVRKIMCQPDYTPSDPMELCNKLLVTCYMASENSSRETKQRASQLASQIGS 440
K G +VL DVR + P+YTPSDP ELC ++LVTCYM + NSS ET+QRA LA QIGS
Sbjct: 434 KSGNEKVLADVRSLTRDPEYTPSDPRELCGRVLVTCYMGTVNSSTETRQRAEDLARQIGS 493
Query: 441 YHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNLALQNIQARIRMVLSYLFAQLM 500
+H I ID AV A++GIF A+G P FK+ GG R+NLALQNIQAR RMVLSYLFAQL
Sbjct: 494 HHKSINIDDAVTASVGIFEKASGTQPKFKASGGSQRENLALQNIQARTRMVLSYLFAQLS 553
Query: 501 XXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFL 560
S+NVDE+LRGY TKYDCSSAD+NPIGGISKTDL+SF+ YA +F L
Sbjct: 554 LWSLDRPGGLLVLASANVDESLRGYFTKYDCSSADLNPIGGISKTDLRSFIIYAMKKFNL 613
Query: 561 PSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSEFGTLRKTYKCGPYSMFEKLV 620
P+L I++APPTAELEPL G+++QTDE DMGMTY+ELS FG LRK CGPYSMF KLV
Sbjct: 614 PALQGIMDAPPTAELEPLEAGKVSQTDEVDMGMTYSELSIFGRLRKISLCGPYSMFMKLV 673
Query: 621 HKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYHAETYSPDDNRFDLRPFLYRVHW 680
++W + C+P +VA+KVKHFFR Y+INRHKMT LTPS HAE+YSPDDNRFDLR FLY W
Sbjct: 674 NEWKESCSPTQVADKVKHFFRSYSINRHKMTTLTPSCHAESYSPDDNRFDLRQFLYNAKW 733
Query: 681 NWQFKTID 688
WQFK ID
Sbjct: 734 PWQFKFID 741
Score = 62.1 bits (144), Expect = 5e-08
Identities = 24/37 (64%), Positives = 32/37 (86%)
Query: 348 GQGGFFLPLSGGVDSSSTACIVFSMCTQICEAIKKGE 384
G+GGFF+PLSGG+DSSS ACIV SMC +C+A+ +G+
Sbjct: 39 GRGGFFIPLSGGIDSSSVACIVHSMCRLVCQAVLEGD 75
>UniRef50_A6R5W3 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 517
Score = 401 bits (988), Expect = e-110
Identities = 218/487 (44%), Positives = 293/487 (60%), Gaps = 21/487 (4%)
Query: 127 RWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQSRHI 186
RWF+ W K R VED+YL R++ +T Q+TVPIGDAVIST D+ IG E CEEL+ P + I
Sbjct: 39 RWFTSWAKPRYVEDYYLERIVGEITGQATVPIGDAVISTYDSAIGIETCEELFTPNNPGI 98
Query: 187 PLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQ-RIYFNGC 245
+ L+GVEI +N SGS+ ELRK +DL++ T + GG YL++N RG DG R+YF+G
Sbjct: 99 HMGLNGVEIFTNSSGSHHELRKLKQRIDLIRHCT-RGGGIYLYANQRGEDGNGRLYFDGS 157
Query: 246 SCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPRIFVDV 305
+ + VNG +V QF L DV+V TA +DLE++RS R + SR + + RI +
Sbjct: 158 AGIFVNGRVVGMSSQFSLKDVDVVTAVVDLEEVRSTRT-SVSRSSQGSQAPAYQRIEAPI 216
Query: 306 SLSDDEDI---HLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGVDS 362
SLS D+ ++ +P I+ Y SPEEEI+LGPACWLWDYLRRS Q GFF
Sbjct: 217 SLSRKSDLLNPNVKPSPDIELEYHSPEEEIALGPACWLWDYLRRSRQSGFF--------- 267
Query: 363 SSTACIVFSMCTQICEAIKKGESQVLYDVRKIMCQPD---YTPSDPMELCNKLLVTCYMA 419
+S A I FSMC + A + G V+ D+R+I+ P+ + P P ELC K+L TCYMA
Sbjct: 268 ASVAIITFSMCRLVVSACRDGNQAVIADMRRIVGVPEDSHWLPDTPQELCGKILHTCYMA 327
Query: 420 SENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNL 479
+ NSS+ET+ RA QLA IGSYH + +D+ V+A +FT T P F GG +NL
Sbjct: 328 TTNSSKETRNRAKQLAKSIGSYHIDLDMDSVVSAISNLFTFVTNFTPRFSVHGGTATENL 387
Query: 480 ALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPI 539
ALQ+ A + + A L+ ++ + + AD+NPI
Sbjct: 388 ALQSKPAN-SGIFKHAPASLLAICSLSFCLWYGRGQGDLPSLFLHQIERVS-DHADLNPI 445
Query: 540 GGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELS 599
G I K+DL +FL +AK F +P + + A PTAELEP+ + TQ+DE MGMTYAELS
Sbjct: 446 GSIDKSDLINFLTWAKVNFDIPIIESFVHAIPTAELEPITE-NYTQSDEDQMGMTYAELS 504
Query: 600 EFGTLRK 606
FG LRK
Sbjct: 505 LFGRLRK 511
Score = 52.8 bits (121), Expect = 3e-05
Identities = 23/42 (54%), Positives = 31/42 (73%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRT 42
M VT++ C+LNQW LDFEGN +RI++SI+ AK GA + T
Sbjct: 1 MAPLVTISTCSLNQWVLDFEGNTSRIIESIRIAKAAGARWFT 42
>UniRef50_A1ZXX0 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;
Bacteria|Rep: NH(3)-dependent NAD(+) synthetase -
Microscilla marina ATCC 23134
Length = 673
Score = 236 bits (578), Expect = 1e-60
Identities = 194/686 (28%), Positives = 317/686 (46%), Gaps = 46/686 (6%)
Query: 5 VTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYL 64
+ VA LNQ LD+E N I+++I A+ G PEL I GY CED F+ +T
Sbjct: 4 IKVAAAILNQTPLDWEQNTQNIIEAINNARNQGVSLLCLPELCITGYGCEDAFYAPNTCA 63
Query: 65 HSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYR 124
+ +VLV++L P + +++ VG+P+ +N +N N K+ K L G +
Sbjct: 64 QALEVLVKIL--PHTQGMVVSVGLPLFVQNQLFNTACLIVNGKVAGFVAKKFLAGQGIHY 121
Query: 125 ETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQSR 184
E RWF W K ++ LP M+ + V +GD IG+EICE+ W
Sbjct: 122 EQRWFKAW-KSGEITTIQLPEMLGG----AEVKVGDVYFDIGGVKIGYEICEDAWVANRP 176
Query: 185 HIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYFNG 244
L G++I+ N S S+ K + V + G +Y+++NL G + R ++G
Sbjct: 177 GRDLYKYGIDILLNPSASHFAFGKLEIRKRFVLEGSRAFGVSYIYANLLGNEAGRAIYDG 236
Query: 245 CSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPRIFVD 304
+ VA NGE+++ G++F + EVTT TID+E R + +N+ A + R+ D
Sbjct: 237 GALVATNGEMIATGKRFSYANWEVTTTTIDIELTRLAQIQNQIPFDTADDYR--HRVQCD 294
Query: 305 VSLSDDEDI--HLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGVDS 362
+ + + HL + ++ EEE S + L+DY+R+S GF + LSGG DS
Sbjct: 295 FTYPECAPMLPHLEQEAWEKSPFIK-EEEFSRAVSLALFDYMRKSFSRGFVVSLSGGADS 353
Query: 363 SSTACIVFSMCTQICEAIKKGESQVLYDVR--KIMCQPDYTPSD-PMELCNKLLVTCYMA 419
++ A + + + E + G + L + K + Q D + ++ P ++ +L+ Y A
Sbjct: 354 AAVAALCYLLIELGIENV--GATYFLNKLGHVKALAQLDQSSANLPHQIAQQLITCAYQA 411
Query: 420 SENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNL 479
+ NS + T A++LA IGS + ++ + + + A G P+ + ++
Sbjct: 412 TRNSGKVTLNAAAKLAKGIGSEFHELDVEPLRENYVSMVSKAIG-RPL-----TWEQDDI 465
Query: 480 ALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPI 539
LQNIQAR+R ++FA L +SN EA GY T +S ++PI
Sbjct: 466 TLQNIQARLRSPGIWMFANL--------KGALLLSTSNRSEAAVGYATMDGDTSGGVSPI 517
Query: 540 GGISKTDLKSFLHYAKN----------RFFLPSLSEILEAPPTAELEPLADGQITQTDEQ 589
GI K L+ +L + +N + LP+L + PTAEL P D QTDE
Sbjct: 518 AGIDKAFLRQWLRWLQNDGLTLATPDQKLTLPALELVNNQQPTAELRP-QDSH--QTDEG 574
Query: 590 DMGMTYAELSEFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHK 649
D+ M Y L + K P L +S + ++ FF+ + N+ K
Sbjct: 575 DL-MPYDLLDDIEEHAIRDKRTPLECLTMLKASYS-QYEVAQLKTWTDKFFKLWCRNQWK 632
Query: 650 MTVLTPSYHAETYSPDDNRFDLRPFL 675
PS+H + + D + P L
Sbjct: 633 RERYAPSFHLDDKNLDPKTWCRFPIL 658
>UniRef50_Q053K5 Cluster: NAD(+) synthase; n=4; Leptospira|Rep:
NAD(+) synthase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain L550)
Length = 644
Score = 231 bits (565), Expect = 5e-59
Identities = 204/673 (30%), Positives = 304/673 (45%), Gaps = 62/673 (9%)
Query: 5 VTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYL 64
V + +L DF GNLN+I + +++ K + PEL I GY CED F +
Sbjct: 4 VRLTSVSLKTRVFDFTGNLNKIKRVLEQEKNSDLILF--PELCISGYGCEDSFFFPRIWK 61
Query: 65 HSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYR 124
SW L ELL P K+ ++ VG+P+ +NC N + I PK L G +
Sbjct: 62 KSWNSLTELL--PLTKNKIVVVGLPIFQNPYLFNCAAVLCNGVVAGIVPKSNLASTGVHY 119
Query: 125 ETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQSR 184
E RWF+ + R+ +F P + S +P G + T G EICE+ W Q
Sbjct: 120 ENRWFTRGEETRK--NFAAP-------DGSVIPFGSLIFETDRFSFGVEICEDSWVLQKP 170
Query: 185 HIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYFNG 244
IPL+ G ++I + S+ K + + + + + YLFSNL G + R+ F G
Sbjct: 171 SIPLAEAGTDLILSPGASHFAFGKQRIRRRIFQENSRRESNVYLFSNLCGNESGRLIFEG 230
Query: 245 CSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKN-RSRCHLAASNKPFPRIFV 303
S + NG+++S Q+ D ++ ID E R+ RAKN R + K F +
Sbjct: 231 GSMIVQNGKLISESQRLFFGDFNFCSSEIDFETSRADRAKNFRPSRNRFNPKKSFEENRI 290
Query: 304 DVSLSDDEDIHLTTNPPIQWHYLSPEEEISL----GPACWLWDYLRRSGQGGFFLPLSGG 359
+ L + N P+ +S EEE L A L+DYL S G+ L LSGG
Sbjct: 291 HLGLKFPKRTS-KINHPLPEPSVSQEEESYLDFTRAVALGLFDYLINSKTKGYTLSLSGG 349
Query: 360 VDSSSTACIVFSMCTQICEAIKKGESQVLYDVRKIMCQPDYTPSDPMELCNKLLVTCYMA 419
DSS +C + A+KK Q L + D+ S +E + +L T Y A
Sbjct: 350 ADSS--------VCALLVTAMKKIAKQELGE--------DFFNSQGIEE-DFILSTLYQA 392
Query: 420 SENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNL 479
+ N+S T+ A LA + S H + IDT V + TG+ NL
Sbjct: 393 TVNNSDRTRSLAKALAEDVKSVHGELTIDTEVQNISQKISEITGI------SFNWNEHNL 446
Query: 480 ALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPI 539
LQNIQARIR + ++ A L + N EA GY T SS + P+
Sbjct: 447 VLQNIQARIRSPIIWMLANL--------NGHLLLSTGNRSEASVGYTTMDGDSSGSVAPL 498
Query: 540 GGISKTDLKSFLHY-AKNRFFL----PSLSEILEAPPTAELEPLADGQITQTDEQDMGMT 594
G+SK + ++ + A+ R + PS+ EI+ +PP+AEL+PL D Q DE+D+ M
Sbjct: 499 AGVSKEFILKWMRFVAEGRDSILPAYPSVKEIVLSPPSAELKPLED---EQEDEKDL-MP 554
Query: 595 YAELSEFGTLRKTYKCGPYSMFEKLVHKWSD--KCTPKEVAEKVKHFFRCYAINRHKMTV 652
Y L + L G +S +L+ K S+ K + E V+ + + N+ K
Sbjct: 555 YPLLQKIEELFIVRGAG-FSEIVQLLSKDSEIQKSVSGGLEESVRKYIALFHRNQWKRER 613
Query: 653 LTPSYHAETYSPD 665
L PS+H + Y D
Sbjct: 614 LPPSFHLDDYGLD 626
>UniRef50_A6DFB9 Cluster: Putative glutamine-dependent NAD(+)
synthetase; n=1; Lentisphaera araneosa HTCC2155|Rep:
Putative glutamine-dependent NAD(+) synthetase -
Lentisphaera araneosa HTCC2155
Length = 638
Score = 214 bits (522), Expect = 8e-54
Identities = 194/676 (28%), Positives = 303/676 (44%), Gaps = 63/676 (9%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
++ T+NQ LD+E NLNRI +I E + PE+ + Y CED F S
Sbjct: 3 LSAITINQTPLDWENNLNRIKSAIAECPSSDFILF--PEMSLTAYGCEDVFLSPHLRERS 60
Query: 67 WQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYRET 126
++L+ELL P K+ +I +G+P++ ++ YN N KII K L +DG + E
Sbjct: 61 QELLLELL--PHSKNQIIAIGLPLEVKSKLYNAVAIIANEKIIGFYCKKHLANDGLHYEK 118
Query: 127 RWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQSRHI 186
RWF W DR VE ++ + VP+GD V + FEIC++ W
Sbjct: 119 RWFEPWP-DRHVEKIHIAGQM--------VPVGDCVFQVNNFRFAFEICQDAWEETRFDS 169
Query: 187 PLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYFNGCS 246
LS +++I N S S+ L K + L+ YL++NL G + R+ ++G
Sbjct: 170 HLSELQLDLILNPSASHFALGKQNLRRQLIIDGAKNFDCHYLYANLNGNEAGRVIYDGAV 229
Query: 247 CVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPRIFVDVS 306
+ +++ ++ L D I + Y + S C + F F +V
Sbjct: 230 FYSDPNKLIYESERLHLDDFRTHKFNIAVSAKEKYTS---SPCIV-----HFSHDFQEVK 281
Query: 307 LSDDEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGVDSSSTA 366
SD +N P L EE L L+DY+R+S GF L LSGGVDS++ A
Sbjct: 282 -SDQ-----VSNFPAS-KQLEAHEEFLLAETLGLYDYMRKSWSKGFILSLSGGVDSATCA 334
Query: 367 CIVFSMCTQICEAIKKGESQVLYDVRKIMCQPDY-TPSDPMELCNKLLVTCYMASENSSR 425
+V+ MC ++ + +++ K+ P + + +LC LL Y AS NS
Sbjct: 335 TLVYHMCERLIVELSLEQTKA-----KLFYIPGTDSVKNAQDLCKLLLSCVYQASANSGP 389
Query: 426 ETKQRASQLASQIGS-YHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNLALQNI 484
T+ A +LA IG+ YHF I+ + G+ A G ++S +LA+QNI
Sbjct: 390 VTETAAEELAKSIGAEYHF-FNIEPVLEIYRGLSQNALGRELAWES------DDLAMQNI 442
Query: 485 QARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGISK 544
QAR R ++ A L +SN EA GY T + ++P+ GI K
Sbjct: 443 QARGRAPGVWMMANL--------KGALLLTTSNRSEAAVGYATMDGDTCGGLSPLAGIGK 494
Query: 545 TDLKSFLHYAK-NRFF----LPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELS 599
L+ +L + N LP+LS + PTAEL P + Q DE+D+ M Y L
Sbjct: 495 VFLREYLREIEINELCGLSKLPALSYVNAQEPTAELRPPGE---EQKDEEDL-MPYEVLD 550
Query: 600 EFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYHA 659
+ L + P +F +L ++D K+ ++ FF ++ N+ K P++H
Sbjct: 551 QIQKLAIRDRLSPKEIFCELRKNYTD----KDCLAYLQRFFTLWSRNQWKRERYAPAFHL 606
Query: 660 ETYSPDDNRFDLRPFL 675
+ S D + P L
Sbjct: 607 DDESLDPKTWCRFPIL 622
>UniRef50_Q8I2P2 Cluster: NAD synthase, putative; n=6;
Plasmodium|Rep: NAD synthase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 839
Score = 167 bits (407), Expect = 7e-40
Identities = 115/349 (32%), Positives = 176/349 (50%), Gaps = 20/349 (5%)
Query: 330 EEISLGPACWLWDYLRRSGQGGFFLPLSGGVDSSSTACIVFSMCTQICEAIKKGESQV-- 387
EE+S A +LW L + GF L +SGG+DSS AC+V+ + I +K+ +
Sbjct: 469 EELSFNCALFLWYILCLTNAKGFVLAISGGIDSSFVACMVYILSIMIEITLKENPDLLDN 528
Query: 388 ----LYDVRKIMCQPDYT----PSDPMELCNKLLVTCYMASENSSRETKQRASQLASQIG 439
L K+ + + ++CNKLL T S+NSS TK + QL+ I
Sbjct: 529 NFCSLELNEKLFIKKVKNLLIDQACRKDICNKLLNTISFPSKNSSENTKCYSEQLSKDIN 588
Query: 440 SYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNLALQNIQARIRMVLSYLFAQL 499
SYH I+ G F+S+GG Q++ LQNIQ+R RM+L+Y F+ L
Sbjct: 589 SYHTTYSIEHLYEFLKSAGEEFLGEDMKFESQGGSTYQDVCLQNIQSRSRMLLTYFFSTL 648
Query: 500 M-----XXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGISKTDLK-SFLHY 553
+ + N+DE++ GY TKYDCSSADIN +G +SK +K + H
Sbjct: 649 ICHKRYFKKKLFNEFLIALATGNLDESITGYYTKYDCSSADINIVGNVSKLLIKETMCHI 708
Query: 554 AKNRFF-LPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSEFGTLRKTYKCGP 612
A + F+ L +++I + P+AEL+PL + QTDE ++ + Y E+ L+ + GP
Sbjct: 709 ANDPFYKLQIINKINQYHPSAELKPLDN---KQTDESELNLKYIEIKLLTILKNNFFLGP 765
Query: 613 YSMFEKLVHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYHAET 661
SM+ L + + E+ K+K FF N HK+ +L PS +E+
Sbjct: 766 SSMYYYLSNYFWTNMPKTEILNKIKIFFTRMLKNTHKLFILPPSIISES 814
Score = 73.7 bits (173), Expect = 1e-11
Identities = 55/192 (28%), Positives = 90/192 (46%), Gaps = 25/192 (13%)
Query: 17 LDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHE-SDTYLHSWQVLVELLK 75
LD+E N +I++SI++ K+L R G ELE+CG +C+ F E D + W L E+LK
Sbjct: 17 LDYENNKLKIVESIKKCKKLNCGIRIGGELELCGVNCKSSFKEIVDLQENCWYYLSEILK 76
Query: 76 SP------TCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMIL--CDDGNYRETR 127
+IL V MPV YNC +A +N +II I PK + D+ +Y +
Sbjct: 77 EKYDEKENLTDNILCFVSMPVYFHKKMYNCELAIYNNEIIFISPKENINKNDEKDYFASY 136
Query: 128 WFSCWTKDRQ----------------VEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIG 171
+ + ++++ E + LP+ I +TNQ G+A++ I
Sbjct: 137 EKNSFIEEKENNIKFNHSDVKIFHNNFEKYVLPQCIQNITNQKETYFGNAILEINGLVIA 196
Query: 172 FEICEELWNPQS 183
++L +S
Sbjct: 197 HIFLDDLIKVES 208
Score = 35.5 bits (78), Expect = 4.9
Identities = 21/88 (23%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Query: 188 LSLDGVEIIS-NGSG-SYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYFNGC 245
++L+ V+I+ NG + ++L Y ++L+ + FSN GCD F+G
Sbjct: 251 INLNSVDILLVNGYVINELQLFNRYF-IELMNLSKLYPNMTLCFSNNSGCDNNFFKFDGF 309
Query: 246 SCVAVNGEIVSRGQQFGLIDVEVTTATI 273
S + N +++++ +F D++V + +
Sbjct: 310 SFICKNNKVLTKNARFTFSDIQVASVNV 337
>UniRef50_A5K6Y4 Cluster: NAD synthase, putative; n=1; Plasmodium
vivax|Rep: NAD synthase, putative - Plasmodium vivax
Length = 867
Score = 153 bits (372), Expect = 1e-35
Identities = 117/367 (31%), Positives = 173/367 (47%), Gaps = 32/367 (8%)
Query: 323 WHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGVDSSSTACIVFSMCTQICEAIK- 381
W + EE+ A +LW L + GF L LSGGVDS +AC+V+ + + +K
Sbjct: 479 WALHNVYEELCFNCALFLWHILHLTNAKGFMLALSGGVDSGFSACMVYLLSIMVELGMKE 538
Query: 382 KGES----QVLYDVRKIMCQPDYTPSDPMEL---------------CNKLLVTCYMASEN 422
+G+ V ++ K + + ++ L CNKLL T + S+N
Sbjct: 539 RGQGAEGGHVQHNQHKRHDRLTHFNNEQFRLKLERLLIDAPCRKAICNKLLNTLCLPSKN 598
Query: 423 SSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNLALQ 482
SS TK A QL+S I SYH ID FKS+GG ++L LQ
Sbjct: 599 SSENTKSYAEQLSSAINSYHTVYCIDGLFAFFKSAGRDFLKEEMKFKSQGGSTYEDLCLQ 658
Query: 483 NIQARIRMVLSYLFAQLMXXXXXX-----XXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
N+Q+R R++++Y F+ L+ + N+DE L GY TKYDCSS DIN
Sbjct: 659 NVQSRSRLLMAYFFSPLICQQRYAPLNLHNEFLLTIATGNLDETLTGYYTKYDCSSGDIN 718
Query: 538 PIGGISKTDLKSFLHYAKN--RFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTY 595
IG +SK +K + N + L + I + P+AEL+PL + QTDE ++ + Y
Sbjct: 719 LIGNVSKILIKETMCLLANDPSYDLSVCNSINQFHPSAELKPLEN---NQTDEDELNLKY 775
Query: 596 AELSEFGTLRKTYKCGPYSMFEKLV-HKWSDKCTPK-EVAEKVKHFFRCYAINRHKMTVL 653
E+ L+ + GP SM L + W + + + +KV+ FF N HK+ VL
Sbjct: 776 LEIKLLAILKNHFFLGPSSMVHYLSRYFWPEALMSRASLVDKVRTFFSRAVRNTHKVLVL 835
Query: 654 TPSYHAE 660
PS E
Sbjct: 836 PPSLAGE 842
Score = 94.3 bits (224), Expect = 1e-17
Identities = 52/139 (37%), Positives = 76/139 (54%), Gaps = 11/139 (7%)
Query: 2 GRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHE-S 60
G K ++ C+++ LD+E N ++++SI+ KEL R G ELE+CG SC+D F E
Sbjct: 4 GSKFGLSCCSISSIPLDYEENKKKVIESIRRCKELNCQVRVGGELELCGVSCKDSFKEVE 63
Query: 61 DTYLHSWQVLVELLK------SPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPK 114
D + W L ELLK P IL V MPV + Y+C+V + +IIL+ PK
Sbjct: 64 DIHEICWHCLSELLKEKCADDGPLMGSILCFVSMPVYFKKQLYSCQVVIYRNQIILLSPK 123
Query: 115 MILCDDGNYRETRWFSCWT 133
L D+ E ++FS W+
Sbjct: 124 ECLSDE----ERKYFSPWS 138
>UniRef50_Q11SE1 Cluster: Glutamine-dependent NAD(+) synthetase;
n=3; Flexibacteraceae|Rep: Glutamine-dependent NAD(+)
synthetase - Cytophaga hutchinsonii (strain ATCC 33406 /
NCIMB 9469)
Length = 626
Score = 130 bits (313), Expect = 2e-28
Identities = 76/269 (28%), Positives = 126/269 (46%), Gaps = 11/269 (4%)
Query: 5 VTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYL 64
+ + +NQ +D+E N+ IL +I+EAK PEL I GY CED F
Sbjct: 4 IRIGGAAVNQTPIDWENNVKNILDAIEEAKNANVEILCLPELCITGYGCEDLFLTDWVAE 63
Query: 65 HSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYR 124
+ + E+ S C DI + +G+P++ ++YNC N + K L ++G +
Sbjct: 64 TAIEYCFEIAAS--CTDITVSLGLPMRIAGITYNCVCLVENGIVKGFSAKQFLANEGVHY 121
Query: 125 ETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQSR 184
ETRWF+ W ++ Y N P GD + + +D IGFEICE+ W
Sbjct: 122 ETRWFTAWPRNHTTTFLY---------NDVKYPFGDVLYNVKDARIGFEICEDAWRTDRV 172
Query: 185 HIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYFNG 244
I G ++ N S S+ K+ + DLV + + Y+++NL G + R+ ++G
Sbjct: 173 GIRHYEKGATLVLNPSASHFAFGKSAIRYDLVIGGSERFDCTYVYANLLGNEAGRMIYDG 232
Query: 245 CSCVAVNGEIVSRGQQFGLIDVEVTTATI 273
+A G+++ R + +V + A I
Sbjct: 233 EVLIAHKGKLIQRNDRLSFKNVNLIYADI 261
Score = 108 bits (259), Expect = 6e-22
Identities = 96/356 (26%), Positives = 157/356 (44%), Gaps = 28/356 (7%)
Query: 326 LSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGVDSSSTACIVFSMCTQ------ICEA 379
L E E + L+DY+R+S GF L LSGG DSS+ A +V M + +
Sbjct: 278 LEKEFEFWEATSLGLFDYMRKSRSKGFVLSLSGGADSSACAIMVAEMIRKGLKELGLTAF 337
Query: 380 IKKGESQVLYDVRKIMCQPDYTPSDPMELCNKLLVTCYMASENSSRETKQRASQLASQIG 439
++K + L+D+ + P ++ L T Y ++ NS ET A LA IG
Sbjct: 338 LQKSNMETLFDLPALQHLP--FEEQAKKITAVFLTTAYQSTRNSGDETYTSAKTLAESIG 395
Query: 440 SYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQNLALQNIQARIRMVLSYLFAQL 499
+ + +D + + A + + + + ++ LQNIQAR R + ++ +
Sbjct: 396 ATFYNWSVDEEIEQ----YKAT--IENVIERPLTWEKDDITLQNIQARGRAPIIWMLTNV 449
Query: 500 MXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFF 559
+SN E GY T ++ I PI G+ K ++S+L +A+
Sbjct: 450 --------KQALLITTSNRSEGDVGYATMDGDTAGGIAPIAGVDKDFIRSWLRWAEKNRN 501
Query: 560 LPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSEFGTLRKTYKCGPYSMFEKL 619
L + + PTAEL P + TQTDE+D+ M Y L+ + P ++ L
Sbjct: 502 QHGLHIVNKLAPTAELRP---SEYTQTDERDL-MPYDVLARIERKAIKERLSPVQVYTAL 557
Query: 620 VHKWSDKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSYHAETYSPDDNRFDLRPFL 675
+ + T E VK FFR ++IN+ K L PS+H + ++ D + P L
Sbjct: 558 LTE--GPYTKNEFKYWVKKFFRLWSINQWKRERLAPSFHMDDFNIDPRSWYRFPIL 611
>UniRef50_Q7MWR3 Cluster: Glutamine-dependent NAD+ synthetase; n=2;
Bacteria|Rep: Glutamine-dependent NAD+ synthetase -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 647
Score = 103 bits (247), Expect = 2e-20
Identities = 82/272 (30%), Positives = 125/272 (45%), Gaps = 12/272 (4%)
Query: 18 DFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHSWQVLVELLKSP 77
D E N+ RI + + EA G T PEL I GYSC D F + + + L L++
Sbjct: 19 DCEYNIERIDRMVHEADAKGVEIMTFPELSITGYSCGDLFFQPFLQERANEALCRLVEQT 78
Query: 78 TCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYRETRWFSCWTKDRQ 137
+++ VGMP++ +N V F KI+ PK L + ++E RWFS
Sbjct: 79 ANTTVMVIVGMPLRVEEKLFNSAVVFQQGKILGAIPKTYLPNYREFQEARWFS------- 131
Query: 138 VEDFYLPRMITAVTNQSTVPIGDAVISTRDTC-IGFEICEELWNPQSRHIPLSLDGVEII 196
+ + T Q +VPIG +I T +G EICE++W P + L L G E+I
Sbjct: 132 --PAHTLQYSTISIGQHSVPIGRNLIFKCGTVGVGIEICEDMWTPFTPGTRLCLYGAEVI 189
Query: 197 SNGSGSYMELRKAYVTVDLVKSATFKSGGAYLF-SNLRGCDGQRIYFNGCSCVAVNGEIV 255
N S S K L+ + + AY++ S+ G I F G + +A GEIV
Sbjct: 190 FNLSSSNENAGKHSYLRSLISGLSSQGICAYVYASSGYGESSTDIVFTGKAFIAEAGEIV 249
Query: 256 SRGQQFGLIDVEVTTATIDLEDIRSYRAKNRS 287
++F + + + ID+ I++ R N S
Sbjct: 250 EEMERF-RYEERMIISDIDVSRIQTERLINSS 280
>UniRef50_Q8ABA5 Cluster: Glutamine-dependent NAD+ synthetase; n=18;
Bacteria|Rep: Glutamine-dependent NAD+ synthetase -
Bacteroides thetaiotaomicron
Length = 641
Score = 98.7 bits (235), Expect = 5e-19
Identities = 87/327 (26%), Positives = 140/327 (42%), Gaps = 14/327 (4%)
Query: 5 VTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYL 64
V VA + D + N+ RI I A+ G PE+ I GY+C D F +
Sbjct: 6 VKVAAAVPHVKVADCKFNVERIESQIAIAEGKGVQIIVFPEMSITGYTCGDLFGQQILLE 65
Query: 65 HSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYR 124
+ L+++L + DI+ VGMPV + N V K++ + K L + +
Sbjct: 66 EAEMGLMQILNNTRQLDIISIVGMPVVVNSTVINAAVVIQKGKVLGVAAKTYLPNYKEFY 125
Query: 125 ETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIG-DAVISTRDTCIGFEICEELWNPQS 183
E RWF+ + + ED T VPIG + + T DT G EICE+LW
Sbjct: 126 EQRWFT--SALQLTED-------TVRLCGQIVPIGANLLFETSDTTFGIEICEDLWATIP 176
Query: 184 RHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLR-GCDGQRIYF 242
L+L G EII N S + K + L+ + + Y+FS+ G + F
Sbjct: 177 PSSSLALQGAEIIFNMSADNEGIGKHHYLCSLISQQSARCIAGYVFSSCGFGESTTDVVF 236
Query: 243 NGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPRIF 302
G + NG +++R ++F ++ ++ + ID+E IR+ R N + A+ P +
Sbjct: 237 AGNGLIYENGSLLARSKRF-CMEEQLIISEIDVERIRAERRINTT--FAASQGNPGDKKA 293
Query: 303 VDVSLSDDEDIHLTTNPPIQWHYLSPE 329
+ V+ LT H P+
Sbjct: 294 ISVATEFVNSKELTLTRDFNSHPFVPQ 320
>UniRef50_Q897Q2 Cluster: NH3-dependent NAD+ synthetase; n=12;
Clostridium|Rep: NH3-dependent NAD+ synthetase -
Clostridium tetani
Length = 639
Score = 94.7 bits (225), Expect = 7e-18
Identities = 76/271 (28%), Positives = 119/271 (43%), Gaps = 15/271 (5%)
Query: 17 LDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHSWQVLVELLKS 76
+D E NL I + I EA Y PEL I YSC D F + S + EL
Sbjct: 27 MDIEFNLTNIKKCINEALNKKVKYIIFPELSITSYSCGDLFLNNQLLNSSLNAIEELCSF 86
Query: 77 PTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYRETRWFSCWTKDR 136
KDIL+ VG P +RN YNC KI+ I PK +C E RWFS K
Sbjct: 87 LKDKDILVSVGSPFLYRNSLYNCAFIIHYGKILGIVPKSNICSS----EQRWFSSGFK-- 140
Query: 137 QVEDFYLPRMITAVTNQSTVPIG-DAVISTRDTCIGFEICEELWNPQSRHIPLSLDGVEI 195
+ + Y+ Q +P G D + + + F + +E +P LSL G I
Sbjct: 141 -IRNEYVSTYF-----QENIPFGIDLIFQSGNFKFSFVLGDEFNSPIPLSSYLSLKGANI 194
Query: 196 ISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQR-IYFNGCSCVAVNGEI 254
I N S S + K+ D +K+ T + Y++S+ + + ++G + G +
Sbjct: 195 IGNLSASNELVGKSQKRRDFLKTTTQRLSCGYIYSSCGVYESTTDLVYSGHLLIGEKGNL 254
Query: 255 VSRGQQFGLIDVEVTTATIDLEDIRSYRAKN 285
+ ++F + E+ ++ID++ + R +N
Sbjct: 255 LKENKRFKR-ENEIIVSSIDVDSLMLNRLRN 284
>UniRef50_A1IW33 Cluster: Putative calmodulin binding protein; n=1;
Phillyrea latifolia|Rep: Putative calmodulin binding
protein - Phillyrea latifolia
Length = 104
Score = 86.2 bits (204), Expect = 3e-15
Identities = 39/85 (45%), Positives = 54/85 (63%)
Query: 124 RETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQS 183
RE RWF+ W + +E+F LP I+ +Q+TVP G I DT + EICEEL++P
Sbjct: 1 RELRWFTAWKQKDHLEEFLLPIEISRSLSQTTVPFGYGYIQFLDTAVAAEICEELFSPIP 60
Query: 184 RHIPLSLDGVEIISNGSGSYMELRK 208
H L+L+GVE+ N SGS+ E+RK
Sbjct: 61 PHAELALNGVEVFMNASGSHQEIRK 85
>UniRef50_Q9X0Y0 Cluster: Probable glutamine-dependent NAD(+)
synthetase (EC 6.3.5.1) (NAD(+) synthase
[glutamine-hydrolyzing]); n=6; Bacteria|Rep: Probable
glutamine-dependent NAD(+) synthetase (EC 6.3.5.1)
(NAD(+) synthase [glutamine-hydrolyzing]) - Thermotoga
maritima
Length = 576
Score = 85.4 bits (202), Expect = 5e-15
Identities = 87/368 (23%), Positives = 159/368 (43%), Gaps = 37/368 (10%)
Query: 3 RKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDT 62
+++ V + LN DFEGNL + +++++ A++ G+ PEL + GY ED
Sbjct: 2 KRLRVTLAQLNPTLGDFEGNLKKAIEALRVAEDRGSDLLVFPELFLPGYPPEDLMLRLSF 61
Query: 63 YLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGN 122
+ + L + + + + +G + +YN + +I+ + K+ L + G
Sbjct: 62 LRENRKYLQKFAQHTRNLGVTVLMGF-IDSDEDAYNAAAVVKDGEILGVYRKISLPNYGV 120
Query: 123 YRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQ 182
+ E R+F + E+ + V IG+ + G ICE++WNP
Sbjct: 121 FDERRYF------KPGEELLV------------VKIGNIKV-------GVTICEDIWNPV 155
Query: 183 SRHIPLSL-DGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIY 241
LSL +GV +I+N S S + K + D + + A + N+ G + ++
Sbjct: 156 EPSASLSLGEGVHLIANLSASPYHVGKPVLRKDYLSMKAYDYHVAMAYCNMVGGQDELVF 215
Query: 242 FNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPRI 301
G V +GE+++ G+ L + E+ T +DL++ + R ++ N P +
Sbjct: 216 DGGSMVVDASGEVINYGK---LFEEEIITVDLDLDENLRVSLVDPRRRYMKTQNYPVKTV 272
Query: 302 FVDVSLSDDEDIHLTTNP-PIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGV 360
NP P++ EEE+ L DY+R++G + LSGG+
Sbjct: 273 EAGNLREKSGHFEPVVNPLPVR------EEEMFRALITGLRDYVRKNGFEKVVIGLSGGM 326
Query: 361 DSSSTACI 368
DSS A I
Sbjct: 327 DSSLVAVI 334
>UniRef50_A5UWQ0 Cluster: NAD+ synthase; n=6; Bacteria|Rep: NAD+
synthase - Roseiflexus sp. RS-1
Length = 686
Score = 79.4 bits (187), Expect = 3e-13
Identities = 77/288 (26%), Positives = 126/288 (43%), Gaps = 15/288 (5%)
Query: 5 VTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYL 64
V VAVC + D N+ R + + A A PEL + Y+C+D F +
Sbjct: 13 VRVAVCIPSLRVADPAYNVTRTIGLAERASVANAAVALFPELGLSAYTCDDLFQQDALLE 72
Query: 65 HSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYR 124
L L+ + ++ VG P++ YNC + ++ +I+ + PK + + +
Sbjct: 73 GVLDALNRLIDASRSLTPVLLVGAPLRIDGALYNCAIVIYHGRILGVVPKSYIPNYREFY 132
Query: 125 ETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGF----EICEELWN 180
E R FS +D L + IT +TVP G+ +I GF EICE++W
Sbjct: 133 EKRQFSA-ARDA------LRQTITLA--GATVPFGNDLIFVAGNVPGFALHAEICEDVWV 183
Query: 181 PQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNL-RGCDGQR 239
P +L G I++N S S + + KA L + + AYL+S G
Sbjct: 184 PAPPSSFAALAGATILANLSASNITIGKADYRRMLCAAQSGTCIAAYLYSAAGPGESTTD 243
Query: 240 IYFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRS 287
+ ++G + + GE+++ +F D + TA IDLE I R + S
Sbjct: 244 LAWDGHALIYELGELLAETGRFA-DDERMITADIDLERIVQERMRTTS 290
>UniRef50_UPI00015BCCB0 Cluster: UPI00015BCCB0 related cluster; n=1;
unknown|Rep: UPI00015BCCB0 UniRef100 entry - unknown
Length = 561
Score = 75.8 bits (178), Expect = 4e-12
Identities = 88/364 (24%), Positives = 155/364 (42%), Gaps = 50/364 (13%)
Query: 5 VTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYL 64
+ V++C +N FE NL + I +AK + PEL +CGY +D + S +L
Sbjct: 6 LNVSLCQINTTVGTFEKNLEKTCDFISKAKNSHII--VFPELSLCGYMPQDIIYSSK-FL 62
Query: 65 HSWQVLVELLKSPTCK-DILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNY 123
++ E LK + D +I VG V+ YN F +++ K L + +
Sbjct: 63 DLNKLYFEKLKEHSKSIDSVIVVGF-VREEKAVYNSLGVLFKGEVLGFYDKRFLPNYNVF 121
Query: 124 RETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQS 183
E R+F K D ++ D GF ICE++W P
Sbjct: 122 DEKRYFKSGEK-------------------------DLLLDINDIRCGFSICEDIWYPDG 156
Query: 184 RHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYFN 243
+L G E++ N + S L+K + +K+ + ++ NL G + + + FN
Sbjct: 157 TERQDALKGAEVLININASPYALKKQTFKENFLKARASDNLCFLVYVNLVGANDE-LVFN 215
Query: 244 GCSCV-AVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPF-PRI 301
G S V G+ +++ + F + ++ ++D++++ + K R+ KP I
Sbjct: 216 GESLVIGPKGDTIAKAKAF---EEDILHVSLDIKEVFT---KRRTDLRWQEVCKPINSNI 269
Query: 302 FVDVSLSD--DEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGG 359
+++S + D IHL+ L EEE+ + DY ++ G L LSGG
Sbjct: 270 SINISKNQRYDNTIHLS---------LPKEEELIKAITLSIKDYFKKQGFSKAILGLSGG 320
Query: 360 VDSS 363
+DS+
Sbjct: 321 IDSA 324
Score = 35.9 bits (79), Expect = 3.7
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 11/108 (10%)
Query: 478 NLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
++A +N+QARIR + + + +SN E+ GY T Y + +
Sbjct: 390 DIADENLQARIRANILFYISN--------KENRIVLSTSNKSESAVGYTTIYGDMAGGFS 441
Query: 538 PIGGISKTDLKSFLHYA-KNRFFLPSLSEILEAPPTAELEPLADGQIT 584
PI + KT++ ++ K++ +P + PP+AEL P Q T
Sbjct: 442 PIKDLYKTEVYEIAYFINKDKEIIP--KNTINKPPSAELRPNQKDQDT 487
>UniRef50_Q97I71 Cluster: NH(3)-dependent NAD(+) synthase (NadE)
fused to amidohydrolase domain; n=1; Clostridium
acetobutylicum|Rep: NH(3)-dependent NAD(+) synthase
(NadE) fused to amidohydrolase domain - Clostridium
acetobutylicum
Length = 642
Score = 73.3 bits (172), Expect = 2e-11
Identities = 70/248 (28%), Positives = 117/248 (47%), Gaps = 21/248 (8%)
Query: 44 PELEICGYSCEDHFHESDTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAF 103
PEL + GY+C D F+++ + L LL S + +++ VGMPV+ N +NC V
Sbjct: 50 PELCVTGYTCGDLFNQNLLIKRAENELNNLLVSTSNINMITAVGMPVKADNQLFNCAVII 109
Query: 104 FNRKIILIRPKMILCDDGNYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVI 163
N I+ + PK + + E R F+ ++ D + VP G+ ++
Sbjct: 110 NNGNILGVVPKTFIPTYNEFYEKRNFA--GAISRISD-------EIILCGKKVPFGENLL 160
Query: 164 ST---RDTCIGFEICEELW---NPQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVK 217
+ CIG +ICE+LW P S H +L+G +I N S S + K+ DLV+
Sbjct: 161 FKDIYSELCIGIDICEDLWVNIPPSSYH---TLNGANLILNLSASDEIVAKSDYRRDLVR 217
Query: 218 SATFKSGGAYLFSNLRGCDG-QRIYFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLE 276
+ K +Y +++ + + F+G S +A NG I+ + +F V A +D+E
Sbjct: 218 LQSAKCITSYAYASSGQTESTSDLVFSGHSIIADNGSIL-KDIKFEEASY-VKYADVDIE 275
Query: 277 DIRSYRAK 284
+ S R K
Sbjct: 276 KLISDRIK 283
>UniRef50_A6Q824 Cluster: Glutamine-dependent NAD+ synthetase; n=2;
unclassified Epsilonproteobacteria|Rep:
Glutamine-dependent NAD+ synthetase - Sulfurovum sp.
(strain NBC37-1)
Length = 631
Score = 72.9 bits (171), Expect = 3e-11
Identities = 70/271 (25%), Positives = 120/271 (44%), Gaps = 17/271 (6%)
Query: 22 NLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHSWQVLVELLKSPTCKD 81
N IL I+EA + PEL + GY+ D F + L +L + D
Sbjct: 22 NAEEILTLIKEAADKEVSVVVFPELTLTGYTASDLFLNQTLLASQNESLQYILNNIEELD 81
Query: 82 ILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYRETRWFSCWTKDRQVEDF 141
++ +G+ + + YNC +I+ I PK L + + E R F V
Sbjct: 82 TIVILGIALLEADRLYNCAAVLQGGEILGIIPKSYLPNKKEFYEKRQF--------VSGR 133
Query: 142 YLPRMITAVTNQSTVPIGDAVIST--RDTCIGFEICEELW--NPQSRHIPLSLDGVEIIS 197
+ R T + + VP G ++ T R+ G EICE+LW P S H ++ +G ++
Sbjct: 134 DIVRTATELLGKE-VPFGVDLLFTDGRNMTFGVEICEDLWAVTPPSNH--MASNGANLLF 190
Query: 198 NGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLR-GCDGQRIYFNGCSCVAVNGEIVS 256
N S S + K +LV++ + + AY++S+ G + G + ++ G ++
Sbjct: 191 NLSASNELIGKHEYREELVRTQSARCMAAYVYSSAGVGESTTDTVYGGHAIISEYGTTLA 250
Query: 257 RGQQFGLIDVEVTTATIDLEDIRSYRAKNRS 287
+ ++F L + + TA IDLE +R R S
Sbjct: 251 QNERFSL-ESSLITADIDLERMRWLRINESS 280
>UniRef50_A4M962 Cluster: NAD+ synthetase; n=2; Thermotogaceae|Rep:
NAD+ synthetase - Petrotoga mobilis SJ95
Length = 575
Score = 68.5 bits (160), Expect = 6e-10
Identities = 85/368 (23%), Positives = 150/368 (40%), Gaps = 38/368 (10%)
Query: 4 KVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTY 63
K+ +++ +N D+ GN+ +I I +A E GA PEL + GY ED ++
Sbjct: 2 KIRISLAQMNSTVGDYPGNVEKIKDFISKADEKGADIILFPELSLNGYPPEDLILKTQFL 61
Query: 64 LHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNY 123
S + + E+ KD++I +G V SYN + +I KM L + +
Sbjct: 62 KDSLKSIEEIQDFSKSKDVVIVLG-AVDWDVESYNSAFVIYKGEIYGSYKKMFLPNYSVF 120
Query: 124 RETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQS 183
E R+F+ +E + R+ +T ICE+LW P
Sbjct: 121 DEKRYFTAGRAPFLME---MERIKIGIT----------------------ICEDLWVPNG 155
Query: 184 RHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYFN 243
+ L+ +G +I N S S + V +++K+ + + N+ G + ++
Sbjct: 156 PAVSLAQNGANLILNLSSSPFYKGRNKVRFEMLKTRASELSSWIAYCNIIGGQDELVFDG 215
Query: 244 GCSCVAVNGEIVSRGQQF--GLIDVEVTTATIDLEDIR-SYRAKNRSRCHLAASNKPFPR 300
G + GEI F GL +++ LE R + R R + +A +
Sbjct: 216 GSVVINPYGEIELSAPSFEEGLYFIDID----PLEPTRANLREGKRKHYNQSAYYESVNT 271
Query: 301 IFVDVSLSDDEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGV 360
I ++ + + I ++ E++ L + DY+ ++G L LSGG+
Sbjct: 272 IKIEKKIREKTPI-----KAVKVDSFDIYEQLYLAVKTGIKDYVLKNGFQKVVLGLSGGI 326
Query: 361 DSSSTACI 368
DSS TA I
Sbjct: 327 DSSLTAAI 334
Score = 35.5 bits (78), Expect = 4.9
Identities = 32/97 (32%), Positives = 40/97 (41%), Gaps = 9/97 (9%)
Query: 482 QNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGG 541
+NIQARIR L F+ N EA GY T Y + +PI
Sbjct: 403 ENIQARIRGNLVMAFSNKFGYLALA--------CGNKSEAATGYATLYGDMAGGFSPIKD 454
Query: 542 ISKTDL-KSFLHYAKNRFFLPSLSEILEAPPTAELEP 577
+ KTDL K Y + + ILE P+AEL P
Sbjct: 455 LYKTDLYKVARKYNELHGKEIIIKSILEKAPSAELRP 491
>UniRef50_P0A5L7 Cluster: Glutamine-dependent NAD(+) synthetase (EC
6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]);
n=15; Bacteria|Rep: Glutamine-dependent NAD(+)
synthetase (EC 6.3.5.1) (NAD(+) synthase
[glutamine-hydrolyzing]) - Mycobacterium bovis
Length = 679
Score = 67.7 bits (158), Expect = 1e-09
Identities = 70/286 (24%), Positives = 124/286 (43%), Gaps = 18/286 (6%)
Query: 5 VTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYL 64
V VA CT + D N +L + + GA PEL + GYS ED +
Sbjct: 12 VRVAACTHHTTIGDPAANAASVLDMARACHDDGAALAVFPELTLSGYSIEDVLLQDSLLD 71
Query: 65 HSWQVLVELL-KSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNY 123
L++L+ +S +L+ VG P++HR+ YN V ++ + PK L +
Sbjct: 72 AVEDALLDLVTESADLLPVLV-VGAPLRHRHRIYNTAVVIHRGAVLGVVPKSYLPTYREF 130
Query: 124 RETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGF----EICEELW 179
E R + +R T + V G ++ GF EICE+++
Sbjct: 131 YERRQMAPGDGERG----------TIRIGGADVAFGTDLLFAASDLPGFVLHVEICEDMF 180
Query: 180 NPQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNL-RGCDGQ 238
P +L G +++N SGS + + +A L +SA+ + AY+++ G
Sbjct: 181 VPMPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASARCLAAYVYAAAGEGESTT 240
Query: 239 RIYFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAK 284
+ ++G + + NG +++ ++F V + A +D E +RS R +
Sbjct: 241 DLAWDGQTMIWENGALLAESERFPK-GVRRSVADVDTELLRSERLR 285
>UniRef50_O29262 Cluster: Probable NH(3)-dependent NAD(+)
synthetase; n=3; Archaea|Rep: Probable NH(3)-dependent
NAD(+) synthetase - Archaeoglobus fulgidus
Length = 247
Score = 61.7 bits (143), Expect = 6e-08
Identities = 47/137 (34%), Positives = 65/137 (47%), Gaps = 21/137 (15%)
Query: 464 LLPIFKSKGGCPRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALR 523
++ +FK K G +A N++ RIRMVL+Y A M + N E +
Sbjct: 90 IVRVFKEKAG-EGSKIAEANLKPRIRMVLNYYHANSMNRLVAG--------TGNKSELMV 140
Query: 524 GYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQI 583
GY TKY D PIG + KT++ Y L I+E P+A L P
Sbjct: 141 GYFTKYGDGGVDFLPIGDLYKTEVFQLAAY------LGVPRRIIEKKPSARLWP------ 188
Query: 584 TQTDEQDMGMTYAELSE 600
QTDE++MG++YAEL E
Sbjct: 189 GQTDEEEMGISYAELDE 205
>UniRef50_Q9CBZ6 Cluster: Glutamine-dependent NAD(+) synthetase (EC
6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]);
n=33; Bacteria|Rep: Glutamine-dependent NAD(+)
synthetase (EC 6.3.5.1) (NAD(+) synthase
[glutamine-hydrolyzing]) - Mycobacterium leprae
Length = 680
Score = 60.9 bits (141), Expect = 1e-07
Identities = 73/308 (23%), Positives = 134/308 (43%), Gaps = 24/308 (7%)
Query: 5 VTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYL 64
V VA CT + D N +L+ ++ + G PEL + GYS ED + D L
Sbjct: 12 VRVAACTHHASIGDPTTNAASVLRLARQCHDDGVAVAVFPELTLSGYSIEDILLQ-DLLL 70
Query: 65 HSWQ--VLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGN 122
+ + VL ++ S +L+ +G P+++R+ YN V ++ + PK L
Sbjct: 71 EAVEDTVLDIVVASADLLPVLV-IGAPLRYRHRIYNTAVIIHRGVVLGVAPKSYLPTYRE 129
Query: 123 YRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGF----EICEEL 178
+ E R + + T P G ++ +G EICE++
Sbjct: 130 FYERRQLAPGDDEHG----------TIGIGDLRAPFGPDLLFAAADLLGLVLHVEICEDM 179
Query: 179 WNPQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNL-RGCDG 237
+ P +L G +++N SGS + + +A L +SA+ + AY+++ G
Sbjct: 180 FVPVPPSAEAALAGATVLANLSGSPITIGRAEDRRLLARSASLRCLAAYVYAAAGEGEST 239
Query: 238 QRIYFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAK----NRSRCHLAA 293
+ ++G + + NG +++ ++F + + A +D E +RS R + N +R A
Sbjct: 240 TDLAWDGQTMIWENGVLLAESERFPKGE-HRSVADVDTELLRSERLRMGTFNDNRRRHRA 298
Query: 294 SNKPFPRI 301
+PF RI
Sbjct: 299 LVEPFRRI 306
>UniRef50_Q7URG9 Cluster: Glutamine-dependent NAD(+) synthetase;
n=1; Pirellula sp.|Rep: Glutamine-dependent NAD(+)
synthetase - Rhodopirellula baltica
Length = 703
Score = 59.3 bits (137), Expect = 3e-07
Identities = 58/226 (25%), Positives = 90/226 (39%), Gaps = 11/226 (4%)
Query: 44 PELEICGYSCEDHFHESDTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAF 103
PEL + Y+C D F S L ++ D I VG+P++ N
Sbjct: 59 PELGLSAYTCGDLFATQTLLDASLDALRTIVTHSHSCDAAIIVGLPLRVGTSVMNVAALV 118
Query: 104 FNRKIILIRPKMILCDDGNYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIG-DAV 162
I + PK L NYRE + + R T ++ +P G D +
Sbjct: 119 RGGVIRGLVPKTFL---PNYRE------FYEARHFRAASATDPATVRIDRQDIPFGTDLL 169
Query: 163 ISTRDTCIGFEICEELWNPQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFK 222
+G EICE+LW P ++ G ++ N S S + KA DLV S + +
Sbjct: 170 FQDGAATLGVEICEDLWVPVPPSSHAAIAGANVVVNLSASNELIGKAQWRRDLVVSQSGR 229
Query: 223 SGGAYLFSNLRGCDG-QRIYFNGCSCVAVNGEIVSRGQQFGLIDVE 267
AY +S+ G + + F G +A NG ++ ++ G D E
Sbjct: 230 LIAAYAYSSAGGGESTSDLVFGGHCLIAENGALIGESRRIGDTDDE 275
>UniRef50_Q2RL06 Cluster: NAD+ synthetase; n=1; Moorella
thermoacetica ATCC 39073|Rep: NAD+ synthetase - Moorella
thermoacetica (strain ATCC 39073)
Length = 577
Score = 57.2 bits (132), Expect = 1e-06
Identities = 93/379 (24%), Positives = 158/379 (41%), Gaps = 57/379 (15%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
+A+ L+ D G+L +I Q++ EA++ GA PEL + GY D D
Sbjct: 3 IAMAQLDPTIGDIGGSLAKIRQAVAEARQHGAGLVIFPELAVTGYPPRDLLCRHDFLERV 62
Query: 67 WQVLVELLKSPTCKDILIDVGMPVQHRN---VSYNCRVAFFNRKIILIRPKMILCDDGNY 123
+ L E + +P ++ I +G PV+ R YN + + ++ + K +L + +
Sbjct: 63 ERALAEDI-APLSRETAIIIGAPVRGRGNPAFLYNAALLYSGGELCGRQDKSLLPNYDVF 121
Query: 124 RETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQ- 182
E+R+F T+ LP + + +G ICE++WN +
Sbjct: 122 DESRYFKPATR-------RLPVFLEGLR------------------LGLTICEDIWNDKD 156
Query: 183 --SRHI----PLS---LDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLR 233
+R + P++ G EI+ N S S K + D+++S K G L+ N
Sbjct: 157 YWNRQLYDIDPVAEMLAQGAEILINISASPYHYGKIALRADMLRSLARKYGRPILYINQV 216
Query: 234 GCDGQRIYFNGCSCVAVNGEIVSRGQQFG----LIDVEVTTATIDLEDIRSYRAKNRSRC 289
G + + I+ + NG +VS F L+D+E A L RA+ +
Sbjct: 217 GGNDELIFDGTSLAIDANGNVVSLAASFAEDLVLLDLERPQAGAALTLKPVKRARPGA-- 274
Query: 290 HLAASNKPFPRIFVDVSLSDDEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQ 349
+ A P L+ +E + + I + Y + LG A DYL ++G
Sbjct: 275 -IPAGVAPEAGRNETEFLTGEE---IVISEDISYVY----RALVLGIA----DYLHKTGF 322
Query: 350 GGFFLPLSGGVDSSSTACI 368
+ LSGG+DSS TA +
Sbjct: 323 RKALVGLSGGIDSSVTAAL 341
Score = 40.7 bits (91), Expect = 0.13
Identities = 47/170 (27%), Positives = 75/170 (44%), Gaps = 27/170 (15%)
Query: 418 MASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQ 477
M S SS ++ A +LA+ +G I I+ G+F A + + GG PR
Sbjct: 356 MPSRYSSPGSRSDARKLAANLGIAFREIPIE-------GMFKAYLEAM----NGGGPPRG 404
Query: 478 NLALQNIQARIR-MVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADI 536
+LA +N+QARIR +L ++ + N E GY T Y S +
Sbjct: 405 DLAEENVQARIRGNILMFI---------SNREGYLTLTTGNKSEMAVGYCTLYGDMSGGL 455
Query: 537 NPIGGISKTDLKSFLHYA-KNRFFLPSLSEILEAPPTAELEPLADGQITQ 585
+ + K + Y ++R +P +++L PP+AEL P GQ+ Q
Sbjct: 456 AVLADVPKVMVYDLARYINRDREIIP--ADVLVKPPSAELRP---GQVDQ 500
>UniRef50_O27554 Cluster: Probable NH(3)-dependent NAD(+)
synthetase; n=3; Methanobacteriaceae|Rep: Probable
NH(3)-dependent NAD(+) synthetase - Methanobacterium
thermoautotrophicum
Length = 266
Score = 56.0 bits (129), Expect = 3e-06
Identities = 50/149 (33%), Positives = 68/149 (45%), Gaps = 23/149 (15%)
Query: 455 LGIFTAATGLLPIFKSKGGCPRQN---LALQNIQARIRMVLSYLFAQLMXXXXXXXXXXX 511
LGI + + PI +S G N LAL N++ R RMV+ Y A +
Sbjct: 82 LGIESETIDIDPIIESLTGLCSHNANELALANLKPRARMVILYYHANSLNRLVAG----- 136
Query: 512 XXXSSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPP 571
+ N E L GY TKY D+ PIGG+ K ++ R +P EI++ PP
Sbjct: 137 ---TGNRTELLLGYFTKYGDGGVDMLPIGGLYKGQVREL----AGRLGVP--PEIIKKPP 187
Query: 572 TAELEPLADGQITQTDEQDMGMTYAELSE 600
TA L QTDE+++GM Y L E
Sbjct: 188 TAGL------WHGQTDEEELGMKYDLLDE 210
>UniRef50_A5UME8 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Methanobrevibacter smithii ATCC 35061|Rep:
NH(3)-dependent NAD(+) synthetase - Methanobrevibacter
smithii (strain PS / ATCC 35061 / DSM 861)
Length = 266
Score = 55.6 bits (128), Expect = 4e-06
Identities = 42/124 (33%), Positives = 58/124 (46%), Gaps = 20/124 (16%)
Query: 477 QNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADI 536
+ LA+ N++ARIRM + Y +A + N E L GY TK+ + DI
Sbjct: 110 EQLAIGNLKARIRMSIIYYYAN--------SKGYLVSGTGNKSEILIGYFTKHGDGACDI 161
Query: 537 NPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYA 596
PIG + KTD+ Y +P EI+ PP A L QTDE ++GMTY
Sbjct: 162 EPIGDLYKTDVFELAKY----MGVP--EEIINKPPRAGL------WNNQTDEDEIGMTYE 209
Query: 597 ELSE 600
L +
Sbjct: 210 NLDK 213
>UniRef50_Q2AET7 Cluster: NH(3)-dependent NAD(+) synthetase; n=3;
Clostridia|Rep: NH(3)-dependent NAD(+) synthetase -
Halothermothrix orenii H 168
Length = 247
Score = 54.4 bits (125), Expect = 1e-05
Identities = 47/155 (30%), Positives = 69/155 (44%), Gaps = 21/155 (13%)
Query: 478 NLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
++A+ NI+ R+RM Y +A + N E GY TKY DI
Sbjct: 107 DMAVANIKPRLRMTTLYYYA--------ARNNYLVVGTDNWSELTVGYFTKYGDGGVDIA 158
Query: 538 PIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAE 597
P+G + KT+++ Y L I++ PPTA L +G Q+DE++MG TY E
Sbjct: 159 PLGRLVKTEVRELARY------LGIPERIIQRPPTA---GLWEG---QSDEKEMGFTYEE 206
Query: 598 LSEFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEV 632
L + L S E L++K K +P V
Sbjct: 207 LDRY-ILTGKATGDTRSKIETLINKNRHKVSPLPV 240
>UniRef50_Q58747 Cluster: Probable NH(3)-dependent NAD(+)
synthetase; n=6; Methanococcales|Rep: Probable
NH(3)-dependent NAD(+) synthetase - Methanococcus
jannaschii
Length = 259
Score = 54.4 bits (125), Expect = 1e-05
Identities = 60/199 (30%), Positives = 91/199 (45%), Gaps = 34/199 (17%)
Query: 457 IFTAATGLLPIFKSKGGCPRQN---LALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXX 513
I + T +L F + G P + +A N++ARIRM + Y FA
Sbjct: 86 IISDITDILKAFGAGGYVPTREFDKIADGNLKARIRMCILYYFAN--------KYNLLVA 137
Query: 514 XSSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTA 573
+SN E GY TK+ + DI PIG + KT++K Y +P EI+E PP+A
Sbjct: 138 GTSNKSEIYVGYGTKHGDIACDIRPIGNLFKTEVKKLAKY----IGVP--KEIIEKPPSA 191
Query: 574 ELEPLADGQITQTDEQDMGMTYAELSEFGTLRKTYKCGPYSMFEKLVHKWSDKCTPKEVA 633
L +G QTDE+++ + Y L T+ K Y+ G + +HK ++ P
Sbjct: 192 ---GLWEG---QTDEEELDIKYETLD---TILKLYEKG---KTPEEIHKETN--IP---L 234
Query: 634 EKVKHFFRCYAINRHKMTV 652
E + + F N HK T+
Sbjct: 235 ETINYVFDLIKKNEHKRTL 253
>UniRef50_UPI0000E87BBA Cluster: NAD synthetase; n=1;
Methylophilales bacterium HTCC2181|Rep: NAD synthetase -
Methylophilales bacterium HTCC2181
Length = 532
Score = 53.6 bits (123), Expect = 2e-05
Identities = 76/271 (28%), Positives = 116/271 (42%), Gaps = 37/271 (13%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
V + LN D N N IL+ ++A GA PEL I GY ED + +
Sbjct: 3 VHLAQLNTIVGDLNFNKNLILKEAEKAMLNGADILLTPELSISGYPPEDLLLDHEFINEC 62
Query: 67 WQVLVEL-LKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYRE 125
+ + E+ +K P DILI +G P+ N YN A + K++ K +L + G + E
Sbjct: 63 DKCVDEIAIKFP---DILIVIGHPMLEDNKLYNSLSALYKSKVLCTYHKRVLPNYGVFDE 119
Query: 126 TRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQSRH 185
R+FS KD +A I+ I F ICE++W +
Sbjct: 120 KRYFS-EGKD------------------------NATINYNGKKISFLICEDVWT-EGLV 153
Query: 186 IPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQ-RIYFNG 244
L GV+II + S E++K +D + + + A ++ N G GQ + F+G
Sbjct: 154 ESLVKQGVDIILCINASPFEVKKQQKRIDQITNKIAGNEVALVYLNALG--GQDNVVFDG 211
Query: 245 CSCVAVNGEIVSRGQQFGLIDVEVTTATIDL 275
S V +G +G F L +T+ IDL
Sbjct: 212 GSFV-YDG---MKGLIFELPQFSLTSEIIDL 238
>UniRef50_Q0W737 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
uncultured methanogenic archaeon RC-I|Rep:
NH(3)-dependent NAD(+) synthetase - Uncultured
methanogenic archaeon RC-I
Length = 269
Score = 53.6 bits (123), Expect = 2e-05
Identities = 42/120 (35%), Positives = 58/120 (48%), Gaps = 20/120 (16%)
Query: 479 LALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINP 538
LA N++ R+RM+++Y A L + N E L GY TKY DI P
Sbjct: 113 LAYANVKPRMRMIVNYFAANL--------DGRVVLGTGNKTELLMGYFTKYGDGGVDILP 164
Query: 539 IGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
IG + KT ++ AK+ L + I+E PP+A L QTDE +MG TY E+
Sbjct: 165 IGDLYKTQVRQM---AKH---LEVPAAIIEKPPSAGL------WAGQTDEAEMGATYEEI 212
>UniRef50_Q8EWK9 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Mycoplasma penetrans|Rep: NH(3)-dependent NAD(+)
synthetase - Mycoplasma penetrans
Length = 243
Score = 53.6 bits (123), Expect = 2e-05
Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 20/127 (15%)
Query: 475 PRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSA 534
P LAL N+++R+RMV Y +AQ +SN DE GY TK+ S +
Sbjct: 98 PDNKLALMNLKSRLRMVCLYYYAQ--------TYNYLVCGTSNADELYTGYFTKFGDSGS 149
Query: 535 DINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMT 594
D P+ ++KTD++ +P S+I+ P+A L Q DE D+ ++
Sbjct: 150 DFIPLANLTKTDVRE----CSKILGVP--SQIINKDPSAGLFE------NQKDEDDLKVS 197
Query: 595 YAELSEF 601
Y E+ F
Sbjct: 198 YLEIDNF 204
>UniRef50_A7JIQ8 Cluster: NAD synthase; n=11; Francisella
tularensis|Rep: NAD synthase - Francisella tularensis
subsp. novicida GA99-3549
Length = 249
Score = 52.0 bits (119), Expect = 5e-05
Identities = 52/184 (28%), Positives = 78/184 (42%), Gaps = 28/184 (15%)
Query: 418 MASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQ 477
+ S+N+ + Q A L + H+ I I A A F A+T ++ RQ
Sbjct: 61 LPSDNNQHQDMQDALDLIEMLNIEHYTISIQPAYEA----FLASTQSFTNLQNN----RQ 112
Query: 478 NLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
+ N QAR+RM+ Y +AQ + N E GY TK+ +ADI
Sbjct: 113 LVIKGNAQARLRMMYLYAYAQ--------QYNRIVIGTDNACEWYMGYFTKFGDGAADIL 164
Query: 538 PIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAE 597
P+ + K+ + Y L IL+ P+A L QTDE +MG+TY E
Sbjct: 165 PLVNLKKSQVFELGKY------LDVPKNILDKAPSAGLWQ------GQTDEDEMGVTYQE 212
Query: 598 LSEF 601
+ +F
Sbjct: 213 IDDF 216
>UniRef50_A0LDN5 Cluster: NAD+ synthetase; n=1; Magnetococcus sp.
MC-1|Rep: NAD+ synthetase - Magnetococcus sp. (strain
MC-1)
Length = 577
Score = 51.6 bits (118), Expect = 7e-05
Identities = 80/366 (21%), Positives = 144/366 (39%), Gaps = 40/366 (10%)
Query: 6 TVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLH 65
T+A+ +N E N ++ + + A+ +GA PEL + GY ED H+
Sbjct: 4 TLAIAQINAHVGALEKNRLAMVSAAKHARRMGAKLVLFPELALTGYPPEDLLHKPSFLRR 63
Query: 66 SWQVLVELLKSPTCKDILIDVGMPVQHRNVS---YNCRVAFFNRKIILIRPKMILCDDGN 122
Q +EL + ++I +D V RN + +N + K L + G
Sbjct: 64 VEQEELELRDA--LREIGVDAIYGVPRRNAAGTLWNAAALIEQGIESQLCIKQALPNYGV 121
Query: 123 YRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQ 182
+ E R+F P T N +P+G ICE++W +
Sbjct: 122 FDERRYFE-------------PGGETHSFNYQEIPMG------------INICEDIWQAK 156
Query: 183 SRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYF 242
L+ G ++I N + S + K +++++ ++G ++ NL G + ++
Sbjct: 157 GAAAQLARQGAKLIINLNASPYRVGKWQDREEIIRARVQETGLPVIYVNLVGGQDELVFD 216
Query: 243 NGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCHLAASNKPFPRIF 302
G + G++V R + F ++ + D ++ + + P
Sbjct: 217 GGSFAMDHTGKLVERCRFFS-EELRLMRVKWDGQNPVVWVPVHGIDNGPVRLVAPMEGGD 275
Query: 303 VDVSLSDDEDIHLTTNPPIQWHYLSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGVDS 362
+ ED+ PP++ P EI L DY+R++G G L LSGGVDS
Sbjct: 276 WRAPRAHGEDV----EPPME-----PLHEIYTAMKIGLHDYVRKNGFQGVVLGLSGGVDS 326
Query: 363 SSTACI 368
+ TA +
Sbjct: 327 ALTAAV 332
>UniRef50_A3EVA0 Cluster: NAD synthase; n=4; Bacteria|Rep: NAD
synthase - Leptospirillum sp. Group II UBA
Length = 592
Score = 51.2 bits (117), Expect = 9e-05
Identities = 70/287 (24%), Positives = 112/287 (39%), Gaps = 32/287 (11%)
Query: 3 RKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDT 62
RK+ +A+ N D GNL I I +A+ PEL + GY ED +
Sbjct: 2 RKLKLALAQTNPIVGDIPGNLAHIKDMILQARSEHVDVVVFPELALTGYPPEDLLLKPSF 61
Query: 63 YLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGN 122
+ + L ELL ++L+ VG V ++ YN K+ I K L + G
Sbjct: 62 IDKNLRALDELLGF--APELLVLVGF-VDRQDDIYNAAAVLHGGKLHGIYRKQYLPNYGV 118
Query: 123 YRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQ 182
+ E R+F E P V+ R +G ICE++W P+
Sbjct: 119 FDENRYFQ--------EGVESP-----------------VLEYRSARLGINICEDIWYPK 153
Query: 183 SRHIPLSLDG-VEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIY 241
+L G E I N S S K V +++ + S + N+ G + ++
Sbjct: 154 GPLYTQTLMGDAECILNLSASPFHAGKREVRENMLCTRAVDSACYIAYVNMVGGQDELVF 213
Query: 242 FNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSR 288
++ +GEI SRG+ F ++ IDL+ + R + R
Sbjct: 214 DGQSLVISPDGEIESRGKAF---QEDLLITEIDLDHVFRVRLHDPRR 257
>UniRef50_Q9HUP3 Cluster: NH(3)-dependent NAD(+) synthetase; n=31;
Bacteria|Rep: NH(3)-dependent NAD(+) synthetase -
Pseudomonas aeruginosa
Length = 275
Score = 51.2 bits (117), Expect = 9e-05
Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 17/126 (13%)
Query: 476 RQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSAD 535
+ + + NI+ARIRMV Y A + + EA+ G+ TK+ + D
Sbjct: 136 KSDFVIGNIKARIRMVAQYAIA--------GARGGLVIGTDHAAEAVMGFFTKFGDGACD 187
Query: 536 INPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTY 595
+ P+ G++K +++ L + ++E PTA+LE L G DE G+TY
Sbjct: 188 LAPLSGLAKHQVRALAR------ALGAPENLVEKIPTADLEDLRPG---HPDEASHGVTY 238
Query: 596 AELSEF 601
AE+ F
Sbjct: 239 AEIDAF 244
>UniRef50_A5ZW40 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus obeum ATCC 29174
Length = 672
Score = 50.4 bits (115), Expect = 2e-04
Identities = 29/101 (28%), Positives = 50/101 (49%)
Query: 30 IQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHSWQVLVELLKSPTCKDILIDVGMP 89
+ E +E GA PEL I Y+C D F + + + LV + + D LI VG+P
Sbjct: 2 VHEMEEQGAKVMVFPELCITAYTCGDLFWQENLLEEAKVQLVRIAEETADVDALIFVGLP 61
Query: 90 VQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYRETRWFS 130
++++ YN + +I+ PK+ L + + E R+F+
Sbjct: 62 LEYKGKLYNVAAGLNHGEILGFVPKINLPNYNEFYEARYFT 102
Score = 41.9 bits (94), Expect = 0.056
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 170 IGFEICEELWNPQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLF 229
I EICE+LW P + + G +I N S S + K LV + + + Y++
Sbjct: 192 IAAEICEDLWVPNPPSVAHAYHGANLIVNLSASDEVVGKDSYRRSLVSAQSARLLCGYIY 251
Query: 230 SNL-RGCDGQRIYFNGCSCVAVNGEIVSRGQQF--GLIDVEVTTATIDLE 276
+ G Q + + G + +A NG I++ ++F G+I ++ +D E
Sbjct: 252 ATAGEGESTQDVVYGGQNLIAENGTILAESRRFVNGIIYADLDIHRLDNE 301
>UniRef50_Q12V31 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Methanococcoides burtonii DSM 6242|Rep: NH(3)-dependent
NAD(+) synthetase - Methanococcoides burtonii (strain
DSM 6242)
Length = 263
Score = 50.4 bits (115), Expect = 2e-04
Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 20/118 (16%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
N++ARIRM + Y +A + + N E L GY TKY DI PIG +
Sbjct: 110 NLKARIRMSMLYYYANMFGRVVMG--------TGNKSEILLGYFTKYGDGGVDIEPIGDL 161
Query: 543 SKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSE 600
KT+++ +P ILE P+A L +G QTDE D+G+TY + +
Sbjct: 162 YKTEVREM----SKMLGVP--ESILEKAPSA---GLWEG---QTDEDDLGVTYETIDK 207
>UniRef50_A7IAS7 Cluster: NAD+ synthetase; n=1; Candidatus
Methanoregula boonei 6A8|Rep: NAD+ synthetase -
Methanoregula boonei (strain 6A8)
Length = 248
Score = 49.6 bits (113), Expect = 3e-04
Identities = 44/135 (32%), Positives = 62/135 (45%), Gaps = 20/135 (14%)
Query: 464 LLPIFKSKGGCPRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALR 523
+L FK+ G L N+ ARIRM + Y A +SN EA+
Sbjct: 91 MLAAFKTIPGFVETPYLLGNLMARIRMTVLYYHAN--------RDHRLVCGTSNRSEAML 142
Query: 524 GYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQI 583
GY TKY ++AD PI + KTD+ K +P ILE P+A L
Sbjct: 143 GYCTKYGDNAADFQPIVHLYKTDVYEMAKEVK----IP--KAILEKTPSAGL------WA 190
Query: 584 TQTDEQDMGMTYAEL 598
Q+DE ++G++YAE+
Sbjct: 191 GQSDEGEIGLSYAEI 205
>UniRef50_Q8RC12 Cluster: NAD synthase; n=5; Clostridia|Rep: NAD
synthase - Thermoanaerobacter tengcongensis
Length = 543
Score = 49.2 bits (112), Expect = 4e-04
Identities = 36/134 (26%), Positives = 67/134 (50%), Gaps = 2/134 (1%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
+A+ +N D + N +I++ I++AK+ A PEL GY +D D ++ +
Sbjct: 3 IALAQINPVVGDIKHNCEKIVKYIEKAKKEKADLVVFPELSTVGYPPKDFLFVKD-FIKT 61
Query: 67 WQVLVELLKSPTCKDILIDVGMPVQHRNVS-YNCRVAFFNRKIILIRPKMILCDDGNYRE 125
+ ++ + P +I + +G + N + YN +NRKII I K +L + + E
Sbjct: 62 NEEMINKIILPATDEIAVILGTVRKDENKNLYNSAFFVYNRKIIEIFDKTLLPNYDVFDE 121
Query: 126 TRWFSCWTKDRQVE 139
R+FS ++ + VE
Sbjct: 122 KRYFSPSSQIKTVE 135
>UniRef50_Q8REA7 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;
Bacteria|Rep: NH(3)-dependent NAD(+) synthetase -
Fusobacterium nucleatum subsp. nucleatum
Length = 258
Score = 49.2 bits (112), Expect = 4e-04
Identities = 31/86 (36%), Positives = 50/86 (58%), Gaps = 12/86 (13%)
Query: 515 SSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAE 574
+SN E GY T++ ++ +NPIG + KT++ Y K +P +E++E P+A+
Sbjct: 136 TSNKTEIYLGYSTQFGDAACALNPIGDLYKTNIWDLSRYLK----IP--NELIEKKPSAD 189
Query: 575 LEPLADGQITQTDEQDMGMTYAELSE 600
L +G QTDEQ+MG+TY E +
Sbjct: 190 ---LWEG---QTDEQEMGLTYKEADQ 209
>UniRef50_Q3SAC7 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
uncultured euryarchaeote Alv-FOS1|Rep: NH(3)-dependent
NAD(+) synthetase - uncultured euryarchaeote Alv-FOS1
Length = 264
Score = 47.6 bits (108), Expect = 0.001
Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 20/121 (16%)
Query: 480 ALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPI 539
A+ N++AR+RM S LF +SN E L GY TKY ++D PI
Sbjct: 106 AVANLKARVRM--SVLFG------IANQESRLVAGTSNKSELLTGYFTKYGDGASDFAPI 157
Query: 540 GGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELS 599
G + KT +++ + +P IL+ P+A L P QTDE ++G+ Y L
Sbjct: 158 GDLYKTQVRAL----AEKIGIP--ERILKKAPSANLLP------GQTDEAELGVDYDTLD 205
Query: 600 E 600
E
Sbjct: 206 E 206
>UniRef50_Q65RB5 Cluster: NH(3)-dependent NAD(+) synthetase; n=3;
Gammaproteobacteria|Rep: NH(3)-dependent NAD(+)
synthetase - Mannheimia succiniciproducens (strain
MBEL55E)
Length = 250
Score = 47.2 bits (107), Expect = 0.001
Identities = 40/138 (28%), Positives = 61/138 (44%), Gaps = 22/138 (15%)
Query: 464 LLPIFKSKGGCPRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALR 523
L P+ S+ R N+ N+ AR+RM+ + AQ + N E L
Sbjct: 96 LSPVLNSEP--ERVNVLKGNLMARLRMIALFTTAQ--------SHRSIVLGTDNAAEWLT 145
Query: 524 GYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQI 583
GY TK+ +AD+ P+ G+ K + Y L +L+ P+A L
Sbjct: 146 GYFTKFGDGAADVLPLAGLRKEQVFELGRY------LGVPQSVLDKKPSAGL------WA 193
Query: 584 TQTDEQDMGMTYAELSEF 601
QTDE +MG+TYAE+ +
Sbjct: 194 GQTDEAEMGVTYAEIDAY 211
>UniRef50_Q9F645 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;
Pseudomonas|Rep: NH(3)-dependent NAD(+) synthetase -
Pseudomonas putida
Length = 275
Score = 47.2 bits (107), Expect = 0.001
Identities = 35/119 (29%), Positives = 55/119 (46%), Gaps = 17/119 (14%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
N +AR+RMV Y A + + EA+ G+ TK+ + D+ P+ G+
Sbjct: 143 NTKARMRMVAQYTIA--------GARGGLVIDTDHAAEAVMGFFTKFGDGACDLAPLSGL 194
Query: 543 SKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSEF 601
K ++ F P ++E PTA+LE LA G + DE G+TYA++ F
Sbjct: 195 VKHQVRDIAR----SFGAPE--SLVEKVPTADLEDLAPG---KPDEASHGVTYAQIDAF 244
>UniRef50_Q84FA9 Cluster: NH3-dependent NAD+ synthetase; n=3;
Cystobacterineae|Rep: NH3-dependent NAD+ synthetase -
Myxococcus xanthus
Length = 630
Score = 47.2 bits (107), Expect = 0.001
Identities = 60/282 (21%), Positives = 97/282 (34%), Gaps = 17/282 (6%)
Query: 3 RKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDT 62
R V + + ++N F N ++ L + G E I GY ED
Sbjct: 2 RLVKLGLASVNTTVGSFTRNTDKALALAGKMAAEGVTLGVFQEQLIAGYPAEDMVQWQGF 61
Query: 63 YLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGN 122
W L + + VG+ V H+ + NC +I+ + PK L
Sbjct: 62 MDRQWPELERFARETAPLPTVFVVGVGVAHQGLRLNCAAVVAGGRILGLVPKEKLPTYSV 121
Query: 123 YRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWNPQ 182
+ E R F P M VP+GD + + E+CE++W+
Sbjct: 122 FYEARTFGRGQ----------PGMAEV---HRGVPLGDYLFHFDFGVVAPEVCEDIWSAD 168
Query: 183 SRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYF 242
+ G E++ N S S L +L+ + +SN G + F
Sbjct: 169 GPMRRRTYSGAELVVNLSASPFRLGFVETRRELIATRAADHQCTIAYSNAVG-SNDGLIF 227
Query: 243 NGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAK 284
+G + NG V +F T A +DL+ RA+
Sbjct: 228 DGGGFLNQNGRHVMETPRF---QEGYTAAVVDLDRTLRLRAE 266
>UniRef50_A1AWG7 Cluster: NAD+ synthetase; n=2; sulfur-oxidizing
symbionts|Rep: NAD+ synthetase - Ruthia magnifica subsp.
Calyptogena magnifica
Length = 626
Score = 47.2 bits (107), Expect = 0.001
Identities = 34/127 (26%), Positives = 57/127 (44%), Gaps = 2/127 (1%)
Query: 3 RKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDT 62
+ + + + +N D +GN +I++ +EA G PEL + GY ED +
Sbjct: 96 KSIKIDIAQINPIVGDLDGNTQKIIKLTKEAHIRGCDLLVFPELSLIGYPPEDLLLREE- 154
Query: 63 YLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGN 122
++ Q V L+ +DI I G P + +V YN N K + + K L + G
Sbjct: 155 FIQQVQDKVTLISQTISEDISIIFGAPSKKNDVLYNGAYLVQNSK-LWVYHKQNLPNYGV 213
Query: 123 YRETRWF 129
+ E R+F
Sbjct: 214 FDEKRYF 220
>UniRef50_Q2FSW6 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Methanospirillum hungatei JF-1|Rep: NH(3)-dependent
NAD(+) synthetase - Methanospirillum hungatei (strain
JF-1 / DSM 864)
Length = 245
Score = 46.8 bits (106), Expect = 0.002
Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 20/118 (16%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
N+ AR RM + Y +A M +SN E L GY TK+ ++AD+ PI +
Sbjct: 109 NLMARTRMTMLYYYANQMNRLVCG--------TSNYTEYLLGYCTKFGDNAADVQPIMHL 160
Query: 543 SKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSE 600
KT + Y LP +++E P+A L QTDE ++GM YA + E
Sbjct: 161 LKTQVWDLARY----LGLP--QKVIEKTPSAGL------WHNQTDEDELGMPYAVIDE 206
>UniRef50_A6EAE3 Cluster: NAD+ synthetase; n=1; Pedobacter sp.
BAL39|Rep: NAD+ synthetase - Pedobacter sp. BAL39
Length = 546
Score = 46.4 bits (105), Expect = 0.003
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 6/127 (4%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
+A+ LN +FE N +I++ +Q A+ GA EL ICGY D F E + ++
Sbjct: 3 IALAQLNYHIGNFESNTKKIIEHVQLARSKGADLVVFAELAICGYPARD-FLEFEEFITL 61
Query: 67 WQVLVELLKSPTCKDILIDVGMPVQHRNVS----YNCRVAFFNRKIILIRPKMILCDDGN 122
+ VE + + C I VG+PV+++ ++ YN V + I K +L +
Sbjct: 62 CEQAVEEI-AAQCTGIACIVGLPVKNQVLAGKDLYNAAVFIEDGDIKQTVRKALLPNYDV 120
Query: 123 YRETRWF 129
+ E R+F
Sbjct: 121 FDEYRYF 127
Score = 39.5 bits (88), Expect = 0.30
Identities = 49/161 (30%), Positives = 64/161 (39%), Gaps = 21/161 (13%)
Query: 418 MASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQ 477
M S+ SS + + A L G H I I +A I L P F+ G P
Sbjct: 323 MPSKYSSDHSVKDALDLVENFGCKHEIIEIKAVADAFDEI------LAPAFQ---GLPF- 372
Query: 478 NLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
NL +NIQAR R V+ + +SN E GY T Y I
Sbjct: 373 NLTEENIQARCRGVVVMAMSNKFGYILLN--------TSNKSECAVGYGTLYGDMCGAIG 424
Query: 538 PIGGISKTDLKSFLHYA-KNRFFLPSLSEILEAPPTAELEP 577
IG + KT + HY K+ +P S + PP+AEL P
Sbjct: 425 VIGDVYKTQVYQLCHYMNKDGILIPENS--IVKPPSAELRP 463
>UniRef50_P75216 Cluster: Probable NH(3)-dependent NAD(+)
synthetase; n=4; Mycoplasma|Rep: Probable
NH(3)-dependent NAD(+) synthetase - Mycoplasma
pneumoniae
Length = 248
Score = 46.4 bits (105), Expect = 0.003
Identities = 40/129 (31%), Positives = 63/129 (48%), Gaps = 23/129 (17%)
Query: 475 PRQNLALQ-NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSS 533
P++ L + N++AR+RM Y AQ + N E GY TK+ +
Sbjct: 101 PQKELMVAGNLKARLRMACLYTHAQ--------KHNYLVLGTGNFIEYSLGYFTKWGDGA 152
Query: 534 ADINPIGGISKTDLKSFLHYAKNRFF-LPSLSEILEAPPTAELEPLADGQITQTDEQDMG 592
D+ P+ + K+D+ YA ++ F +P L ++E PTA L QTDE +MG
Sbjct: 153 CDVAPLAFLLKSDV-----YALSQHFNVPEL--VIERAPTASLFA------GQTDEAEMG 199
Query: 593 MTYAELSEF 601
+TY EL ++
Sbjct: 200 LTYKELDQY 208
>UniRef50_Q7VHF9 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Helicobacter hepaticus|Rep: NH(3)-dependent NAD(+)
synthetase - Helicobacter hepaticus
Length = 274
Score = 45.2 bits (102), Expect = 0.006
Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 20/125 (16%)
Query: 477 QNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADI 536
Q + + N ARIRM + Y A +SN E L GY T + + I
Sbjct: 111 QKMRMGNFCARIRMTMLYDCAS--------ADNALVLGTSNKSEILLGYGTIFGDLAYAI 162
Query: 537 NPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYA 596
NPIGG+ KT + +F A N +P EI+ P+A+L Q+DE D+G YA
Sbjct: 163 NPIGGLYKTQIFAFAR-ALN---VP--QEIIAKKPSADL------FANQSDETDLGYNYA 210
Query: 597 ELSEF 601
++ F
Sbjct: 211 DIDTF 215
>UniRef50_A7I243 Cluster: NAD+ synthetase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: NAD+ synthetase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 247
Score = 44.8 bits (101), Expect = 0.008
Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 20/136 (14%)
Query: 465 LPIFKSKGGCPRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRG 524
L F+ + L N AR+RM L Y F+ + +SN+ E + G
Sbjct: 89 LQAFRDSRNDEISRIRLGNFAARVRMSLLYDFSAKISGVVVG--------TSNLSERMLG 140
Query: 525 YMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQIT 584
Y T Y + NPIG + KT++ +AK FL +I+ P+A+ L +G
Sbjct: 141 YGTIYGDLACAFNPIGELFKTEI---FEFAK---FLNIDEKIISKAPSAD---LWEG--- 188
Query: 585 QTDEQDMGMTYAELSE 600
Q+DE D+G YA L E
Sbjct: 189 QSDEGDLGYDYASLDE 204
>UniRef50_A6SYJ8 Cluster: NH(3)-dependent NAD(+) synthetase; n=11;
Proteobacteria|Rep: NH(3)-dependent NAD(+) synthetase -
Janthinobacterium sp. (strain Marseille) (Minibacterium
massiliensis)
Length = 309
Score = 44.4 bits (100), Expect = 0.010
Identities = 40/160 (25%), Positives = 68/160 (42%), Gaps = 21/160 (13%)
Query: 446 LIDTAVNAALGIFTAATGLLPIFKSKGGCPR----QNLALQNIQARIRMVLSYLFAQLMX 501
LI + I A+ G+L K+ G R ++ L NI+AR RM+ Y A
Sbjct: 132 LIQPDETLTVNIKPASDGMLASLKAGGLAFRDEKEEDFILGNIKARQRMIAQYAVA---- 187
Query: 502 XXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLP 561
+ + EAL G+ TK+ + D+ P+ G++K ++S +
Sbjct: 188 ----GHAGGLVIGTDHAAEALMGFFTKHGDGACDVTPLSGLNKRQIRSIAQHC------G 237
Query: 562 SLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSEF 601
+ + PTA+LE L + DE G+ Y ++ +F
Sbjct: 238 ASVALAYKVPTADLETLTP---LKPDEVSFGLPYDDIDDF 274
>UniRef50_A5IKN7 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=7;
Thermotogaceae|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Thermotoga petrophila
RKU-1
Length = 267
Score = 44.4 bits (100), Expect = 0.010
Identities = 35/97 (36%), Positives = 43/97 (44%)
Query: 18 DFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHSWQVLVELLKSP 77
DFEGNL RI Q I+ A GA PEL I GY+ ++ + S +LLK
Sbjct: 14 DFEGNLERIEQFIEMAVSEGAEVVVFPELTISGYTWDEAILKRGALFFSEVAKKKLLKLS 73
Query: 78 TCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPK 114
ILI VG P N V F +K +L K
Sbjct: 74 REGQILIAVGTPRIVLGKLRNSLVIFKKKKELLFYDK 110
>UniRef50_Q8PZP6 Cluster: NH(3)-dependent NAD(+) synthetase; n=3;
Methanosarcina|Rep: NH(3)-dependent NAD(+) synthetase -
Methanosarcina mazei (Methanosarcina frisia)
Length = 256
Score = 44.4 bits (100), Expect = 0.010
Identities = 36/118 (30%), Positives = 53/118 (44%), Gaps = 20/118 (16%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
N++AR RM L Y A + + N E L GY TKY D+ PIGG+
Sbjct: 111 NLKARTRMSLLYFHANRLNRMVIG--------TGNKTEILLGYYTKYGDGGVDLEPIGGL 162
Query: 543 SKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSE 600
KT + +R +P ++ P+A L QTDE D+G++Y ++ E
Sbjct: 163 YKTGVWEL----SSRLGIP--ESLITKKPSAGL------WAGQTDEADLGISYVKVDE 208
>UniRef50_UPI0000DAE70E Cluster: hypothetical protein
Rgryl_01001070; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01001070 - Rickettsiella
grylli
Length = 543
Score = 44.0 bits (99), Expect = 0.014
Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 2/128 (1%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
+AV N D +GN IL +IQ+AK PEL + GY ED D +
Sbjct: 6 IAVAQSNFLVGDIQGNTQIILDNIQKAKHASVDLLIFPELALTGYPPEDLLLRED-FKQQ 64
Query: 67 WQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYRET 126
Q +++++ + L+ +G P ++N N+KI+ K L + G + E
Sbjct: 65 IQQALKIIQEKSIGVTLL-LGYPDFSSQGTFNAVSQLENKKIVNTYHKQYLPNYGVFDEC 123
Query: 127 RWFSCWTK 134
R+F T+
Sbjct: 124 RYFKSGTQ 131
>UniRef50_Q5ZXJ7 Cluster: Glutamine dependent NAD+ synthetase; n=5;
Proteobacteria|Rep: Glutamine dependent NAD+ synthetase
- Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 536
Score = 44.0 bits (99), Expect = 0.014
Identities = 64/257 (24%), Positives = 106/257 (41%), Gaps = 34/257 (13%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHES 60
M +T+ + +N + N +I+ IQ + + PEL + GY ED
Sbjct: 1 MNAPLTILMAQINPTVGAIDANTKKIIDVIQNHQANHDVI-IFPELTLSGYPAEDLLFRK 59
Query: 61 DTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDD 120
+ + L ++ T KD + VG P+ H YN F+ + I K L +
Sbjct: 60 EYHDKIMLNLQDI--QDTTKDCYVIVGHPMIHIGDCYNGFSIFYQGEKIRAYHKQKLPNY 117
Query: 121 GNYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWN 180
G + E R+F+ KD V+S ++ +GF ICE+LW
Sbjct: 118 GVFDEARYFTPGKKD------------------------PCVLSIKNHKLGFCICEDLW- 152
Query: 181 PQSRHIPLSLD-GVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQ- 238
Q + LD G+ I+ + + S + RK + +L++S K G ++ N G GQ
Sbjct: 153 -QKGPVDDLLDSGISILISLNASPFDYRKYQLREELLRSYA-KRGVYIIYVNQIG--GQD 208
Query: 239 RIYFNGCSCVAVNGEIV 255
+ F+G S N I+
Sbjct: 209 DLLFDGQSLAMDNQGII 225
Score = 36.3 bits (80), Expect = 2.8
Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 16/117 (13%)
Query: 482 QNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGG 541
+NIQARIR +L LM +SN E GY T Y + +
Sbjct: 365 ENIQARIRGML------LMALSNKTGKMVLT--TSNKSETAVGYATLYGDMAGGFAVLKD 416
Query: 542 ISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
+ KT + + Y +N+ L ++ PP+AEL+P QTD QD Y EL
Sbjct: 417 VLKTQVYELVRY-RNKISLVIPERVITRPPSAELKP------NQTD-QDSLPEYGEL 465
>UniRef50_A5IZA1 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;
Mycoplasma|Rep: NH(3)-dependent NAD(+) synthetase -
Mycoplasma agalactiae
Length = 270
Score = 44.0 bits (99), Expect = 0.014
Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 20/123 (16%)
Query: 479 LALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINP 538
L++ NI+ R+RM+ Y +AQ + N DE GY TK+ D+ P
Sbjct: 122 LSISNIKPRLRMIALYAYAQ--------QNNYLVMGTDNQDEYFIGYFTKHGDGGVDLLP 173
Query: 539 IGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
I + K++++ Y +P I+ P+A L +G Q+DE ++G TY EL
Sbjct: 174 ISKLLKSEVRMMAKYLN----VP--ESIINKKPSA---GLWEG---QSDEDELGFTYHEL 221
Query: 599 SEF 601
+
Sbjct: 222 DSY 224
>UniRef50_A1S062 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Thermofilum
pendens Hrk 5|Rep: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase - Thermofilum pendens
(strain Hrk 5)
Length = 279
Score = 44.0 bits (99), Expect = 0.014
Identities = 64/293 (21%), Positives = 129/293 (44%), Gaps = 29/293 (9%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHE- 59
M ++ V V ++ D NL + L+ ++ A+ELG PEL + GY D +E
Sbjct: 1 MRDRLRVGVAQIHSLLGDVRRNLEKHLEYVERARELGVEVLAFPELSLTGYLLRDLAYEV 60
Query: 60 SDTYLHSWQVLVELLKSPTCKDILIDVGMPVQHRNVSYNCRVAFF-NRKIILIRPKMILC 118
SD + + L E+ ++ + + + VG+ + R Y VA + + + K+ L
Sbjct: 61 SDA---AREALGEIAEA--SRGLCVLVGLVHEPRAGIYENSVAVVRDGSVAGVVSKLYLP 115
Query: 119 DDGNYRETRWFSCWTKDRQ-VEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEE 177
D G + E+R+F + R+ V + R+ + + P + + R + F
Sbjct: 116 DYGLFEESRYFREGSCSREGVFECGGWRVAPIICEDAWHPEPAELAARRGADVVF----- 170
Query: 178 LWNPQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDG 237
H + G + +G + + +A V++A + +F+N G +
Sbjct: 171 ------IHASSPIRG--LYGSGEANIERVWEAIAVTRAVENACY-----VVFANRVGPED 217
Query: 238 QRIYFNGCSCVAVNGEIVSRGQQFGLIDVEVTTATIDLEDIRSYRAKNRSRCH 290
+ ++ G VA +GE+V+R ++ ++ E+ A +DL +R+ R + + H
Sbjct: 218 EEYFWGGSMVVAPDGEVVARAKK---MEEELLVADLDLYRLRASRRFSSFKRH 267
>UniRef50_A1I7L4 Cluster: Nitrilase/cyanide hydratase and
apolipoprotein N-acyltransferase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Nitrilase/cyanide
hydratase and apolipoprotein N-acyltransferase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 316
Score = 43.6 bits (98), Expect = 0.018
Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
VA+C LD + NL ++ I + +E GA PEL + GY +H++ + S
Sbjct: 3 VAICQTKPALLDVQTNLESVIAHIHKCREQGAQLVVFPELALTGYFVGLQYHKAALRMDS 62
Query: 67 WQVLVELLKSPTCKDILIDVGMPVQHRNVS-YNCRVAFFNRKIILIRPKMILCDDGNYRE 125
Q + L + T K VG + R+++ YN + + +I+ K+ L + G + E
Sbjct: 63 DQ--IRKLAAAT-KGTAAVVGFIEESRSMNFYNSALIAVDGEILFAYRKLNLPNYGAFEE 119
Query: 126 TRWFS 130
++F+
Sbjct: 120 RKFFA 124
>UniRef50_Q6F0U4 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;
Entomoplasmatales|Rep: NH(3)-dependent NAD(+) synthetase
- Mesoplasma florum (Acholeplasma florum)
Length = 244
Score = 42.7 bits (96), Expect = 0.032
Identities = 43/164 (26%), Positives = 69/164 (42%), Gaps = 23/164 (14%)
Query: 475 PRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSA 534
P LA+ N +AR+RM Y AQ + N+DE GY TK+
Sbjct: 101 PEHKLAIANAKARLRMTTLYTVAQ--------TNSYLVLGTDNLDEWHIGYFTKFGDGGV 152
Query: 535 DINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMT 594
D+ P+ + K +++ A +P + I+ PTA L QTDE ++G+T
Sbjct: 153 DMVPLVHLLKREVRE----AARILGVP--TSIINRAPTASLWE------DQTDESELGIT 200
Query: 595 YAELSEF--GTLR-KTYKCGPYSMFEKLVHKWSDKCTPKEVAEK 635
Y ++ + G + + K + + HK + PKE K
Sbjct: 201 YDQIDAYLAGEINDENVKSRVDHLHKISEHKRNGAVAPKEFKRK 244
>UniRef50_A7H731 Cluster: NAD+ synthetase; n=4; Bacteria|Rep: NAD+
synthetase - Anaeromyxobacter sp. Fw109-5
Length = 567
Score = 42.7 bits (96), Expect = 0.032
Identities = 59/270 (21%), Positives = 103/270 (38%), Gaps = 38/270 (14%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
+A+ +N DF GN +I + A+ GA PEL +CGY D + +
Sbjct: 7 IALAQVNTTVGDFAGNAAKIRAVTERARAEGATLVVFPELALCGYPPRDFLDLPEFLERA 66
Query: 67 WQVLVEL-LKSPTCKDILIDVGMPVQHRNVS----YNCRVAFFNRKIILIRPKMILCDDG 121
+ L EL + +D+ I VG P YN + ++ + K +L
Sbjct: 67 ARTLAELAAPAEWSRDVAIVVGFPEGVAGAPPPGVYNAAALIADGRVAAVGRKSLLPTYD 126
Query: 122 NYRETRWFSCWTKDRQVEDFYLPRMITAVTNQSTVPIGDAVISTRDTCIGFEICEELWN- 180
+ ETR+F LP ++ ST V +G +CE++WN
Sbjct: 127 VFDETRYF-------------LP------SDSSTAADAGGV----GLRLGLSVCEDVWND 163
Query: 181 ------PQSRHIPLS---LDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSN 231
P+ P++ G ++ N S S + K + ++ ++ G + N
Sbjct: 164 KRFWVHPRYARDPIAELVRGGAGLVVNISASPYAMGKPGLRERMLSASAAGHGAPIAYVN 223
Query: 232 LRGCDGQRIYFNGCSCVAVNGEIVSRGQQF 261
G + ++ G V +G I++R F
Sbjct: 224 QVGGNDALVFDGGSMLVGSDGAILARAPLF 253
Score = 39.5 bits (88), Expect = 0.30
Identities = 50/169 (29%), Positives = 68/169 (40%), Gaps = 22/169 (13%)
Query: 418 MASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQ 477
M S SS +++ A+ LA +G I I+ A LG AA G P
Sbjct: 342 MPSRYSSGHSREDAAALADHLGIPFKEISIEPMHAAFLGQIEAAEGK----------PLG 391
Query: 478 NLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
+LA QN+QARIR QL+ + N E GY T Y + +
Sbjct: 392 DLAEQNVQARIR-------GQLL-MALSNDTGGLVLSTGNKSELAVGYCTLYGDMAGGLA 443
Query: 538 PIGGISKTDLKSFLHYAKNRFFLPSLSE-ILEAPPTAELEPLADGQITQ 585
IG + KT + A R + E PP+AEL+P GQ+ Q
Sbjct: 444 VIGDVPKTLVYRVSRAANARAGRTLIPERTFTKPPSAELKP---GQVDQ 489
>UniRef50_Q6L0D1 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;
Thermoplasmatales|Rep: NH(3)-dependent NAD(+) synthetase
- Picrophilus torridus
Length = 249
Score = 42.7 bits (96), Expect = 0.032
Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 20/116 (17%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
NI++R+R V+ Y A L+ ++N E L GY TKY + D+ PI +
Sbjct: 106 NIRSRVRSVILYYNANLLNGLVVG--------TTNRTEYLIGYFTKYGDGACDLEPIEHL 157
Query: 543 SKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
K+D++ Y K +P I+ P+A L D Q DE ++GM Y EL
Sbjct: 158 YKSDVRELASYLK----VP--ESIIRKKPSAGL--WGD----QYDEDELGMGYEEL 201
>UniRef50_Q5F8V6 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;
Neisseria|Rep: NH(3)-dependent NAD(+) synthetase -
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Length = 273
Score = 42.3 bits (95), Expect = 0.042
Identities = 36/122 (29%), Positives = 57/122 (46%), Gaps = 18/122 (14%)
Query: 477 QNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADI 536
Q L+L N ++R+RM+ Y + Q+ + V++ G+ TKY DI
Sbjct: 119 QPLSLANARSRLRMLTLYYYGQI-------HGLLVTGTGNKVEDFGVGFFTKYGDGGVDI 171
Query: 537 NPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYA 596
+PI ++KT + L I +APPT + L D + +TDE+ MG +Y
Sbjct: 172 SPIADLTKTQVYRLAE------ALGVDEAIQKAPPT---DGLWDTE--RTDEEQMGASYP 220
Query: 597 EL 598
EL
Sbjct: 221 EL 222
>UniRef50_Q97WN9 Cluster: NH(3)-dependent NAD(+) synthetase; n=5;
Sulfolobaceae|Rep: NH(3)-dependent NAD(+) synthetase -
Sulfolobus solfataricus
Length = 278
Score = 41.9 bits (94), Expect = 0.056
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 8/66 (12%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
NI+AR+RM++ Y +AQ++ + + E L GY TKY D+ PIG +
Sbjct: 117 NIKARVRMIILYAYAQMLDYLVVG--------TGDKSELLLGYFTKYGDGGVDVLPIGDL 168
Query: 543 SKTDLK 548
KT ++
Sbjct: 169 YKTQVR 174
>UniRef50_A0RPV6 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Campylobacter fetus subsp. fetus 82-40|Rep:
NH(3)-dependent NAD(+) synthetase - Campylobacter fetus
subsp. fetus (strain 82-40)
Length = 248
Score = 41.5 bits (93), Expect = 0.074
Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 20/116 (17%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
NI AR+RM+L Y +SN E L GY T Y ++ +NPIG I
Sbjct: 105 NIIARVRMILLY--------DNSAKLGTLVAGTSNKSERLLGYGTIYGDTACALNPIGDI 156
Query: 543 SKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
K+DL FL +AK +L I+ P+A+ L +G Q DE ++G Y+ +
Sbjct: 157 YKSDL--FL-FAK---YLEIDENIINKAPSAD---LWEG---QKDEDEIGFAYSSV 200
Score = 35.5 bits (78), Expect = 4.9
Identities = 16/41 (39%), Positives = 29/41 (70%), Gaps = 4/41 (9%)
Query: 338 CWLWDYLRRSGQGGFFLPLSGGVDSSSTACIVFSMCTQICE 378
C+L YL++SG GF + +SGG+DS+ IV ++C+++ +
Sbjct: 13 CFLDKYLKQSGASGFSIGVSGGLDSA----IVATLCSKVAK 49
>UniRef50_Q8U4I9 Cluster: NH(3)-dependent NAD(+) synthetase; n=4;
Thermococcaceae|Rep: NH(3)-dependent NAD(+) synthetase -
Pyrococcus furiosus
Length = 257
Score = 41.5 bits (93), Expect = 0.074
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 20/121 (16%)
Query: 480 ALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPI 539
+L NI AR+RMVL Y +A + +SN E L GY TK+ ++D P+
Sbjct: 102 SLGNIMARVRMVLLYSYANSLGRLVLG--------TSNRSEFLTGYFTKWGDGASDYAPL 153
Query: 540 GGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELS 599
I KT++ + I+E P+A L +G QTDE ++G++Y L
Sbjct: 154 INIYKTEVWEVAR------IIGVPQSIVEKKPSA---GLWEG---QTDEDELGISYKLLD 201
Query: 600 E 600
E
Sbjct: 202 E 202
>UniRef50_Q0AX10 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
NH(3)-dependent NAD(+) synthetase - Syntrophomonas
wolfei subsp. wolfei (strain Goettingen)
Length = 249
Score = 41.1 bits (92), Expect = 0.098
Identities = 35/120 (29%), Positives = 54/120 (45%), Gaps = 22/120 (18%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
NI++R+RM+ Y AQ +SN E GY TKY + D+ +G +
Sbjct: 112 NIKSRLRMMALYYSAQ--------ARNYLVLGTSNKSELCVGYSTKYGDAGVDLQLLGDL 163
Query: 543 SKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQIT-QTDEQDMGMTYAELSEF 601
K ++ L++ L P T +P + G + QTDE +MG+TY EL +
Sbjct: 164 LKREVYE-------------LAQFLGVPETIVNKPPSGGLWSGQTDEGEMGLTYEELDNY 210
>UniRef50_Q98PU6 Cluster: NH(3)-dependent NAD(+) synthetase; n=5;
Mycoplasma|Rep: NH(3)-dependent NAD(+) synthetase -
Mycoplasma pulmonis
Length = 257
Score = 41.1 bits (92), Expect = 0.098
Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 22/131 (16%)
Query: 476 RQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSAD 535
+ LA NI+ R+RM Y AQ + N+DE GY TKY D
Sbjct: 110 KNKLAKANIKPRLRMASLYAMAQ--------EKDYLVLGTDNLDEWYLGYFTKYGDGGVD 161
Query: 536 INPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTY 595
+ PI ++K+++ S K I+E P+A L Q DE+++G +Y
Sbjct: 162 LLPISYLTKSEVISLAQIYKVD------KGIIEKKPSAGLWE------NQEDEKELGYSY 209
Query: 596 AELSEFGTLRK 606
+E+ F LRK
Sbjct: 210 SEVDLF--LRK 218
>UniRef50_Q73MV7 Cluster: Glutamine-dependent NAD+ synthetase,
putative; n=1; Treponema denticola|Rep:
Glutamine-dependent NAD+ synthetase, putative -
Treponema denticola
Length = 650
Score = 40.7 bits (91), Expect = 0.13
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 6/101 (5%)
Query: 18 DFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHES---DTYLHSWQVLVELL 74
D E N+N LQ I++A++ GA P L I G S F +S + L + ++L E
Sbjct: 30 DIEENVNIHLQEIKKAEKDGANLILFPRLSITGASLGSVFKQSLLIEKALDAVKILAEKT 89
Query: 75 KSPTCKDILIDVGMPVQHRNVSYNCRVAFFNRKIILIRPKM 115
K I+ +G+P +R Y C N K+I + P +
Sbjct: 90 KQ---FSIVSVIGLPFLYRQNLYTCSAVIENGKLIALVPHL 127
>UniRef50_Q6MGT5 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Bdellovibrio bacteriovorus|Rep: NH(3)-dependent NAD(+)
synthetase - Bdellovibrio bacteriovorus
Length = 540
Score = 40.7 bits (91), Expect = 0.13
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 515 SSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFL-HYAKNRFFLPSLSEILEAPPTA 573
+ N E GY T Y + P+G ++K + + +Y K +P EI++ PP+A
Sbjct: 403 TGNKSEYASGYSTLYGDMCGGLAPLGDLTKAQVYALARYYNKQGEVIPQ--EIIDRPPSA 460
Query: 574 ELEPLADGQ--ITQTDEQDMGMTY 595
EL P Q + + D+ D +TY
Sbjct: 461 ELRPNQKDQDSLPEYDDLDKAVTY 484
>UniRef50_Q30SA2 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;
Campylobacterales|Rep: NH(3)-dependent NAD(+) synthetase
- Thiomicrospira denitrificans (strain ATCC 33889 / DSM
1351)
Length = 257
Score = 40.7 bits (91), Expect = 0.13
Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 20/123 (16%)
Query: 478 NLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
NL N+ AR+RM S LF +SN E + GY T Y + +N
Sbjct: 102 NLRRGNLSARLRM--STLF------DLSAKHNALVLGTSNKSELMLGYGTLYGDLACALN 153
Query: 538 PIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAE 597
PIG + K+++ Y L + I++ P+A+L Q+DE D+G TY++
Sbjct: 154 PIGDLYKSEVYELAEY------LNVTNSIMKKAPSADL------WAGQSDEADLGYTYSQ 201
Query: 598 LSE 600
L +
Sbjct: 202 LDK 204
>UniRef50_A6DBJ9 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Caminibacter mediatlanticus TB-2|Rep: NH(3)-dependent
NAD(+) synthetase - Caminibacter mediatlanticus TB-2
Length = 272
Score = 40.7 bits (91), Expect = 0.13
Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 20/118 (16%)
Query: 481 LQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIG 540
L N AR+RM + Y +SN E + GY T Y ++ +NPIG
Sbjct: 110 LGNFSARMRMAILY--------DKSAELNALVIGTSNKSELMLGYGTLYGDLASALNPIG 161
Query: 541 GISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
+ K+++ F Y L I++ PP+A+L Q+DE ++G +Y+E+
Sbjct: 162 DLYKSEIFEFAKY------LGVPESIIKKPPSADLWQ------GQSDEAELGYSYSEI 207
>UniRef50_Q9HNM7 Cluster: NH(3)-dependent NAD(+) synthetase; n=5;
Halobacteriaceae|Rep: NH(3)-dependent NAD(+) synthetase
- Halobacterium salinarium (Halobacterium halobium)
Length = 268
Score = 40.7 bits (91), Expect = 0.13
Identities = 40/134 (29%), Positives = 60/134 (44%), Gaps = 23/134 (17%)
Query: 462 TGLLPIFKSKGGCPRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEA 521
T L +F G +A+ N +AR R V++Y A + N EA
Sbjct: 107 TQLTDVFPDAAG---DEVAVGNARARTRAVINYFVAN--------HGDGVVLGTGNRAEA 155
Query: 522 LRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADG 581
+ GY TKY + D NPIG + K ++ A++ L +++ PTAEL AD
Sbjct: 156 MTGYYTKYGDQAVDCNPIGNLYKMQVRQL---ARD---LGVPEDLVTKAPTAEL--WAD- 206
Query: 582 QITQTDEQDMGMTY 595
QTD ++G+ Y
Sbjct: 207 ---QTDAGELGVDY 217
>UniRef50_Q9PPB0 Cluster: NH(3)-dependent NAD(+) synthetase; n=13;
Campylobacter|Rep: NH(3)-dependent NAD(+) synthetase -
Campylobacter jejuni
Length = 246
Score = 40.7 bits (91), Expect = 0.13
Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 20/122 (16%)
Query: 479 LALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINP 538
++L N ARIRM L Y ++ L +SN E L GY T Y + NP
Sbjct: 102 VSLGNFAARIRMSLLYDYSALKNSLVIG--------TSNKSELLLGYGTIYGDLACAFNP 153
Query: 539 IGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
IG + K+++ + Y L ++ P+A+L Q+DE D+G +Y ++
Sbjct: 154 IGSLYKSEIYALAKY------LNLHENFIKKAPSADLWE------NQSDEADLGFSYTKI 201
Query: 599 SE 600
E
Sbjct: 202 DE 203
>UniRef50_A3H5Q2 Cluster: NH(3)-dependent NAD(+) synthetase; n=3;
Thermoprotei|Rep: NH(3)-dependent NAD(+) synthetase -
Caldivirga maquilingensis IC-167
Length = 285
Score = 40.3 bits (90), Expect = 0.17
Identities = 50/181 (27%), Positives = 78/181 (43%), Gaps = 32/181 (17%)
Query: 418 MASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGCPRQ 477
M + + E + A QLA +G + + ID I + + +P FK +
Sbjct: 69 MPYKTTPPEDVKDAIQLAQMLGVKYDVVNIDP-------IRASFSSTIPAFKES-----E 116
Query: 478 NLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
+A NI ARIRM + Y +A L + + E L GY TKY DI
Sbjct: 117 IVANGNILARIRMTILYYYANL--------NNMIVAGTGDKSELLIGYFTKYGDGGVDIL 168
Query: 538 PIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAE 597
PIG + K+ ++ R LP I+ P + L +G QT E ++G++YA+
Sbjct: 169 PIGDVYKSQVRML----GRRLGLP--DSIVTKPSSPR---LWEG---QTAEGELGVSYAD 216
Query: 598 L 598
+
Sbjct: 217 I 217
>UniRef50_Q9PQ30 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Ureaplasma parvum|Rep: NH(3)-dependent NAD(+) synthetase
- Ureaplasma parvum (Ureaplasma urealyticum biotype 1)
Length = 255
Score = 39.9 bits (89), Expect = 0.23
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 10/90 (11%)
Query: 517 NVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELE 576
N DE + G+ TKY S+AD + G+ LK ++ + LP ++IL PT
Sbjct: 137 NYDEYILGFFTKYGDSAADYYMLIGL----LKKHIYELGAYYHLP--NKILNRAPT---- 186
Query: 577 PLADGQITQTDEQDMGMTYAELSEFGTLRK 606
P + +TDE G TY +L +F RK
Sbjct: 187 PANEDDEHKTDESFFGFTYNDLDQFLLYRK 216
>UniRef50_Q4AHT4 Cluster: NAD+ synthase; n=1; Chlorobium
phaeobacteroides BS1|Rep: NAD+ synthase - Chlorobium
phaeobacteroides BS1
Length = 524
Score = 39.9 bits (89), Expect = 0.23
Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 11/101 (10%)
Query: 478 NLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
N+A +N+QAR+R VL LM +SN EA GY T Y + ++
Sbjct: 351 NIAEENLQARVRGVL------LMGLSNKFGYILLN--TSNKSEAAVGYSTLYGDMNGGLS 402
Query: 538 PIGGISKTDLKSFLHYA-KNRFFLPSLSEILEAPPTAELEP 577
IG + KT + Y +++ +P I+ PP+AEL P
Sbjct: 403 VIGDVYKTKVFELARYINRDQELIP--DNIITKPPSAELRP 441
>UniRef50_A6C9U7 Cluster: NAD+ synthetase; n=1; Planctomyces maris
DSM 8797|Rep: NAD+ synthetase - Planctomyces maris DSM
8797
Length = 558
Score = 39.9 bits (89), Expect = 0.23
Identities = 32/126 (25%), Positives = 56/126 (44%), Gaps = 4/126 (3%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
+A+ LN D GN +IL+++ A++ G PEL +CGY +D + ++ +
Sbjct: 3 IALAQLNPTVGDLSGNCQKILETVNRAEQSGVDLVLFPELVLCGYPPKDILLR-EGFIEA 61
Query: 67 WQVLVELLKSPTCKDILIDVGMPVQH---RNVSYNCRVAFFNRKIILIRPKMILCDDGNY 123
V+ L + DI + +G P + N F KI K++L + +
Sbjct: 62 CDHAVDRLAAQLNPDIGVVIGHPTGRDLPQGRIANAASLLFQGKIDSQIHKLLLPNYDVF 121
Query: 124 RETRWF 129
E R+F
Sbjct: 122 DEQRYF 127
>UniRef50_A1W6S4 Cluster: NAD+ synthetase; n=64; Proteobacteria|Rep:
NAD+ synthetase - Acidovorax sp. (strain JS42)
Length = 554
Score = 39.9 bits (89), Expect = 0.23
Identities = 63/269 (23%), Positives = 104/269 (38%), Gaps = 33/269 (12%)
Query: 18 DFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHSWQVLVELLKSP 77
D GN +IL + ++A GA PEL +CGY+ ED + ++ + + +E L +
Sbjct: 16 DVPGNAQKILAAARDAHAAGARLLLTPELALCGYAAED-LYLRPAFVQACEQALEGLAAA 74
Query: 78 TC--KDILIDVGMP--VQHRNVSYNCRVAFFNRKIILIRPKMILCDDGNYRETRWFSCWT 133
T + + VG P V H V R N +L R R +
Sbjct: 75 TADWPGLTVVVGHPRRVAH-GVGEGGRGLCHNAASVL-------------RAGRIEHTYA 120
Query: 134 KDRQVEDFYLPRMITAVTNQSTVPIGD--AVISTRDTCIGFEICEELWNPQSRHIPLSLD 191
K YLP + VP GD V +G ICE+ W P
Sbjct: 121 KQ------YLPNYEVFDERRYFVP-GDENCVFEVEGVRMGLLICEDAWYPGPARSAREA- 172
Query: 192 GVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLFSNLRGCDGQRIYFNGCSCVAVN 251
G +++ + S L KA +++ ++G ++++L G + ++ + +
Sbjct: 173 GAQVLVTLNASPYHLGKAVEREQVMRERVQETGLPLVYAHLVGGQDEVVFEGRSFALNAD 232
Query: 252 GEIVSRGQQFG----LIDVEVTTATIDLE 276
G + +R F LI V+ A I LE
Sbjct: 233 GNVAARAPGFEEKTLLIKVQQAQAAIVLE 261
>UniRef50_Q3IUR2 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Natronomonas pharaonis DSM 2160|Rep: NH(3)-dependent
NAD(+) synthetase - Natronomonas pharaonis (strain DSM
2160 / ATCC 35678)
Length = 270
Score = 39.9 bits (89), Expect = 0.23
Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 22/114 (19%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
N+ AR+RM + YL A M ++N E L GY TK+ +AD+ P+ +
Sbjct: 124 NLVARLRMSMLYLTANAMERLVVG--------TTNRSEHLLGYFTKHGDGAADVLPLAHL 175
Query: 543 SKTDLKSFLHYAKNRFFLPSLSEILEAPP-TAELEPLADGQITQTDEQDMGMTY 595
KT+++ L++ LE PP AE P A Q+D D G Y
Sbjct: 176 YKTEVE-------------RLADALEVPPFIAEKPPTAGFYPGQSDRADFGAPY 216
>UniRef50_Q5SH30 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;
Thermus thermophilus|Rep: NH(3)-dependent NAD(+)
synthetase - Thermus thermophilus (strain HB8 / ATCC
27634 / DSM 579)
Length = 281
Score = 39.5 bits (88), Expect = 0.30
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 12/81 (14%)
Query: 515 SSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAE 574
+ N E L GY T + + +NP+G + KT + + L E++ PPTA+
Sbjct: 145 TGNKTERLFGYFTWHGDDTPPVNPLGDLYKTQVWRLAEH------LGVPEEVVRKPPTAD 198
Query: 575 LEPLADGQITQTDEQDMGMTY 595
L P QTDE D+G+ Y
Sbjct: 199 LIP------GQTDEADLGLRY 213
>UniRef50_A3DP41 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Staphylothermus marinus F1|Rep: NH(3)-dependent NAD(+)
synthetase - Staphylothermus marinus (strain ATCC 43588
/ DSM 3639 / F1)
Length = 275
Score = 39.1 bits (87), Expect = 0.39
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 478 NLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADIN 537
N+ N++ARIRM + Y +A L + + E L GY TKY DI
Sbjct: 115 NIPTGNLRARIRMNILYYYANL--------HNYIVVGTGDRSEILIGYFTKYGDGGVDIL 166
Query: 538 PIGGISKTDLKSFLHY 553
PIG + KT ++ Y
Sbjct: 167 PIGSLFKTQVRKMGDY 182
>UniRef50_O25096 Cluster: NH(3)-dependent NAD(+) synthetase; n=5;
Helicobacteraceae|Rep: NH(3)-dependent NAD(+) synthetase
- Helicobacter pylori (Campylobacter pylori)
Length = 260
Score = 39.1 bits (87), Expect = 0.39
Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 12/82 (14%)
Query: 515 SSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAE 574
+SN E + GY T + + INPIG + KT+ ++ R +P +IL PP+A+
Sbjct: 132 TSNKSERMLGYGTLFGDLACAINPIGELFKTE----VYELARRLNIP--KKILNKPPSAD 185
Query: 575 LEPLADGQITQTDEQDMGMTYA 596
L + Q+DE+D+G Y+
Sbjct: 186 L------FVGQSDEKDLGYPYS 201
>UniRef50_Q1UZK0 Cluster: NH(3)-dependent NAD(+) synthetase; n=2;
Candidatus Pelagibacter ubique|Rep: NH(3)-dependent
NAD(+) synthetase - Candidatus Pelagibacter ubique
HTCC1002
Length = 245
Score = 38.7 bits (86), Expect = 0.52
Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 18/122 (14%)
Query: 479 LALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINP 538
L + N +ARIRM Y A + V++ G+ TKY DI+P
Sbjct: 108 LGMANSRARIRMTTLYQVA-------AANKGIVVGTGNKVEDFGVGFYTKYGDGGVDISP 160
Query: 539 IGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
I +K+++ K+ + L EI++A PT L DG +TDE +G+ Y EL
Sbjct: 161 IADCNKSEV---WEIGKS---INILQEIIDAAPTDGL--WDDG---RTDEGQLGLKYEEL 209
Query: 599 SE 600
E
Sbjct: 210 EE 211
>UniRef50_Q9RYV5 Cluster: NH(3)-dependent NAD(+) synthetase; n=120;
Bacteria|Rep: NH(3)-dependent NAD(+) synthetase -
Deinococcus radiodurans
Length = 287
Score = 38.7 bits (86), Expect = 0.52
Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 17/119 (14%)
Query: 483 NIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGGI 542
N++AR RMV Y A + + EAL G+ TKY D+ P+ G+
Sbjct: 142 NVKARERMVAQYALA--------GQENLLVVGTDHAAEALTGFYTKYGDGGVDLTPLSGL 193
Query: 543 SKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAELSEF 601
+K L + L + PTA+LE D + DE +G+TYA++ +
Sbjct: 194 TKRQGAQLLAH------LGAPEGTWRKVPTADLE---DDRPGLPDEVALGVTYAQIDAY 243
>UniRef50_A0HL74 Cluster: NAD+ synthetase; n=4; Comamonadaceae|Rep:
NAD+ synthetase - Comamonas testosteroni KF-1
Length = 567
Score = 38.3 bits (85), Expect = 0.69
Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 13/113 (11%)
Query: 468 FKSKGGCPRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMT 527
F++ G P + LAL+N+QAR R F+ + N E GY T
Sbjct: 372 FEASFGEPLKGLALENLQARARGTTLMEFSN--------AFGHLLLTTGNKSEVSVGYCT 423
Query: 528 KYDCSSADINPIGGISKT---DLKSFLHYAKNRFFLPSLSEILEAPPTAELEP 577
Y ++ + +G + KT +L ++ R +P I++ PP+AEL P
Sbjct: 424 LYGDTNGGLGLLGDLYKTEVFELSRHINQHAGRELIP--QAIIDKPPSAELAP 474
>UniRef50_Q8KEX2 Cluster: NH(3)-dependent NAD(+) synthetase; n=15;
Bacteria|Rep: NH(3)-dependent NAD(+) synthetase -
Chlorobium tepidum
Length = 277
Score = 38.3 bits (85), Expect = 0.69
Identities = 25/86 (29%), Positives = 46/86 (53%), Gaps = 12/86 (13%)
Query: 515 SSNVDEALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAE 574
+SN E + GY T + ++ +NPIG + KT + + L + +++ PP+A+
Sbjct: 138 TSNKTELMLGYGTMFGDMASAVNPIGDLYKTQIFGLARH------LGIPAPLIDKPPSAD 191
Query: 575 LEPLADGQITQTDEQDMGMTYAELSE 600
L +G Q+DE D+G +Y E+ +
Sbjct: 192 ---LWEG---QSDEADLGFSYEEVDQ 211
>UniRef50_Q1MRS6 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Lawsonia intracellularis PHE/MN1-00|Rep: NH(3)-dependent
NAD(+) synthetase - Lawsonia intracellularis (strain
PHE/MN1-00)
Length = 525
Score = 37.9 bits (84), Expect = 0.91
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 16/107 (14%)
Query: 482 QNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINPIGG 541
+NIQ+RIR VL LM + N E GY T Y + + PIG
Sbjct: 370 ENIQSRIRGVL------LMAISNKFGWMVLS--TGNKSERAVGYCTLYGDTCGGLAPIGD 421
Query: 542 ISKTD---LKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQ 585
+ KT+ L + + +K + +P + +L PP+AEL P GQ+ Q
Sbjct: 422 LYKTEVYHLAQWYNQSKQKDIIP--TSVLTKPPSAELRP---GQLDQ 463
>UniRef50_Q8ZPU5 Cluster: NH(3)-dependent NAD(+) synthetase; n=25;
Proteobacteria|Rep: NH(3)-dependent NAD(+) synthetase -
Salmonella typhimurium
Length = 275
Score = 37.9 bits (84), Expect = 0.91
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 520 EALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLA 579
EA+ G+ TKY DINP+ ++K K L L + + PTA+LE
Sbjct: 165 EAITGFFTKYGDGGTDINPLHRLNKRQGKQLL------AALGCPEHLYKKVPTADLE--- 215
Query: 580 DGQITQTDEQDMGMTYAELSEF 601
D + + DE +G+TY + ++
Sbjct: 216 DDRPSLPDEAALGVTYDNIDDY 237
>UniRef50_Q2S5I3 Cluster: NAD(+) synthase; n=1; Salinibacter ruber
DSM 13855|Rep: NAD(+) synthase - Salinibacter ruber
(strain DSM 13855)
Length = 567
Score = 37.5 bits (83), Expect = 1.2
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHS 66
+A+ +N D EGN +IL + A + GA PEL + GY ED E+ + +
Sbjct: 3 IALAQINPTIGDLEGNREKILDYARRADDRGADLVVFPELCVTGYPPED-LLENPFFKRA 61
Query: 67 WQVLVELLKSPTCKDILIDVGMPV 90
Q V+ L D+ + +G PV
Sbjct: 62 VQRTVDHLARALPADLGVIIGAPV 85
>UniRef50_Q2GJM2 Cluster: NH(3)-dependent NAD(+) synthetase; n=1;
Anaplasma phagocytophilum HZ|Rep: NH(3)-dependent NAD(+)
synthetase - Anaplasma phagocytophilum (strain HZ)
Length = 600
Score = 37.5 bits (83), Expect = 1.2
Identities = 45/178 (25%), Positives = 72/178 (40%), Gaps = 26/178 (14%)
Query: 415 TCYMASENSSRETKQRASQLASQIGSYHFPILIDTAVNAALGIFTAATGLLPIFKSKGGC 474
T + + ++S+ + A + A +G++H + I+ A T L K+
Sbjct: 380 TFMLTTRHTSQSSVTDAQRCAELLGTHHEVVSIEEA------FCTCIESL----KTYIDT 429
Query: 475 PRQNLALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSA 534
P N AL+N+Q+RIR + YL A + N E L GYMT Y +
Sbjct: 430 PTPNNALENMQSRIRGM--YLMA------ISNANSLLLLATGNKSELLTGYMTLYGDTCG 481
Query: 535 DINPIGGISKTDLKSFLHYAKNRFFLPSL--------SEILEAPPTAELEPLADGQIT 584
PI + KT + + + + SL I+ P+AEL+P Q T
Sbjct: 482 GYAPINNVYKTKVYDLVKWRNSNIPANSLCRKMHVIPENIITKAPSAELKPNQTDQDT 539
>UniRef50_Q83RG5 Cluster: NH(3)-dependent NAD(+) synthetase; n=61;
Bacteria|Rep: NH(3)-dependent NAD(+) synthetase -
Shigella flexneri
Length = 275
Score = 37.5 bits (83), Expect = 1.2
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 9/82 (10%)
Query: 520 EALRGYMTKYDCSSADINPIGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLA 579
EA+ G+ TKY DINP+ ++K K L L + + PTA+LE
Sbjct: 165 EAITGFFTKYGDGGTDINPLYRLNKRQGKQLL------TALGCPEHLYKKAPTADLE--- 215
Query: 580 DGQITQTDEQDMGMTYAELSEF 601
D + + DE +G+TY + ++
Sbjct: 216 DDRPSLPDEVALGVTYDNIDDY 237
>UniRef50_Q3A713 Cluster: Predicted amidohydrolase family protein;
n=1; Pelobacter carbinolicus DSM 2380|Rep: Predicted
amidohydrolase family protein - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 262
Score = 37.1 bits (82), Expect = 1.6
Identities = 20/49 (40%), Positives = 28/49 (57%)
Query: 7 VAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCED 55
+A L A D GN N +++ ++ A +LGA + PEL ICGYS D
Sbjct: 11 IAFLHLAPVAGDVGGNRNLLIKGMEAAAKLGAQWVLTPELCICGYSFAD 59
>UniRef50_A3JH40 Cluster: Carbon-nitrogen hydrolase family protein;
n=1; Marinobacter sp. ELB17|Rep: Carbon-nitrogen
hydrolase family protein - Marinobacter sp. ELB17
Length = 277
Score = 37.1 bits (82), Expect = 1.6
Identities = 34/130 (26%), Positives = 54/130 (41%), Gaps = 4/130 (3%)
Query: 1 MGRKVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHES 60
M K+ VAV +N L+ + NL + +A+E GA PEL + GY +
Sbjct: 1 MTSKIRVAVAQINPELLEVKHNLALHCDYVAQAREQGAELLLFPELSLSGYQVSRNAPAI 60
Query: 61 DTYLHSWQVLVELLKSPTCKDILIDVGMPVQHR-NVSYNCRVAFFNRKIILIRPKMILCD 119
+ H VL L + I + G + R +N + K++ I+ K+ L
Sbjct: 61 AMHAHD-PVLHALAREAV--GITVVAGFVEEGRPGELFNAMAYLRDGKVMHIQRKINLPT 117
Query: 120 DGNYRETRWF 129
G E +WF
Sbjct: 118 YGGLEEGKWF 127
>UniRef50_Q39DY3 Cluster: NAD(+) synthase; n=44;
Betaproteobacteria|Rep: NAD(+) synthase - Burkholderia
sp. (strain 383) (Burkholderia cepacia (strain ATCC
17760/ NCIB 9086 / R18194))
Length = 568
Score = 36.7 bits (81), Expect = 2.1
Identities = 19/52 (36%), Positives = 27/52 (51%)
Query: 4 KVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCED 55
K +A+ +N DF GN+ RI+ + + A GA PEL + GY ED
Sbjct: 2 KTRLALAQINVTVGDFAGNVARIVAAARAAHNDGAQLMVAPELALSGYPPED 53
>UniRef50_Q8KCC8 Cluster: Carbon-nitrogen hydrolase family protein;
n=10; Chlorobiaceae|Rep: Carbon-nitrogen hydrolase
family protein - Chlorobium tepidum
Length = 286
Score = 36.3 bits (80), Expect = 2.8
Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 11/137 (8%)
Query: 4 KVTVAVCTLNQWALDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTY 63
++ A CTL +FE NL R +++I+ A GA PEL + GY+ +D D
Sbjct: 7 RIVQADCTL----ANFEENLERHIKAIETAIRDGADAIAFPELSLTGYNVQD--AAQDMA 60
Query: 64 LHSWQVLVELLKSPTCKDILIDV-GMPVQHRNVSYNCRVAFFNRKIILIRPKMILCDDGN 122
+H ++ L+ +DI I G+ + YN F + + K+ L G
Sbjct: 61 MHIDDRRLDALRE-LSRDICIFCGGIELSDDYGVYNSAFMFEDGAGRSVHRKIYLPTYGM 119
Query: 123 YRETRWFSCWTKDRQVE 139
+ E R+FS RQ+E
Sbjct: 120 FEELRYFSA---GRQIE 133
>UniRef50_Q2PY75 Cluster: NH(3)-dependent NAD(+) synthetase; n=18;
Bacteria|Rep: NH(3)-dependent NAD(+) synthetase -
uncultured marine bacterium Ant29B7
Length = 341
Score = 36.3 bits (80), Expect = 2.8
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 18/120 (15%)
Query: 479 LALQNIQARIRMVLSYLFAQLMXXXXXXXXXXXXXXSSNVDEALRGYMTKYDCSSADINP 538
LAL N +AR+RM Y AQ + V++ G+ TKY D++P
Sbjct: 180 LALINTRARLRMTTLYAEAQ-------AHGLLVVGTGNKVEDFGIGFYTKYGDGGVDLSP 232
Query: 539 IGGISKTDLKSFLHYAKNRFFLPSLSEILEAPPTAELEPLADGQITQTDEQDMGMTYAEL 598
I ++K+++++ F+ + IL A P+ L DG ++DE +G +Y EL
Sbjct: 233 IADLTKSEVQALAR------FVGVPAAILTATPSDGL--WDDG---RSDEMQIGASYPEL 281
Score = 34.7 bits (76), Expect = 8.5
Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 13/78 (16%)
Query: 291 LAASNKPFPRIFVDVS-LSDDEDIHLTTNP-PIQWHYLSPEEEISLGPACWLWDYLRRSG 348
L+ + P RI +D + +S +DI TNP PI H S WL Y ++G
Sbjct: 45 LSIAVNPAIRITLDGAFISVPKDIVPMTNPDPIVSHITS-----------WLIAYASKAG 93
Query: 349 QGGFFLPLSGGVDSSSTA 366
GF L +SGGVDS+ TA
Sbjct: 94 AKGFVLGVSGGVDSALTA 111
>UniRef50_Q2N5E0 Cluster: Serine proteinase; n=1; Erythrobacter
litoralis HTCC2594|Rep: Serine proteinase - Erythrobacter
litoralis (strain HTCC2594)
Length = 1818
Score = 35.9 bits (79), Expect = 3.7
Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 141 FYLPRMI-TAVTNQSTVPIGDAVISTR-DTCIGFEICEELWNPQSRHIPLSLDGVEIISN 198
FYL + V + TV I ++ I+T D IGFEI + ++LDG++I ++
Sbjct: 1092 FYLAGLTGDMVDSDYTVSITESTIATAGDDAIGFEIAGVGGAFTGSELTMALDGIDIATS 1151
Query: 199 GSGSY 203
GSGS+
Sbjct: 1152 GSGSH 1156
>UniRef50_A6CCB9 Cluster: Predicted amidohydrolase; n=1;
Planctomyces maris DSM 8797|Rep: Predicted
amidohydrolase - Planctomyces maris DSM 8797
Length = 282
Score = 35.5 bits (78), Expect = 4.9
Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 17 LDFEGNLNRILQSIQEAKELGALYRTGPELEICGYSCEDHFHESDTYLHSWQVLVELLKS 76
+D EGNL+RI++ I+E GA PE + GY C E+ Y S
Sbjct: 13 MDKEGNLSRIIEKIKETAAAGASLTVFPECALTGY-CFASLEEALPYAESIPGPSTDRLQ 71
Query: 77 PTCKDI--LIDVGMPVQHRNVSYNCRV 101
C+++ + VGM Q YN V
Sbjct: 72 EICRELNHSVVVGMLEQAEQGVYNAAV 98
>UniRef50_Q8G5Q1 Cluster: Glutamine-dependent NAD(+) synthetase;
n=3; Bifidobacterium|Rep: Glutamine-dependent NAD(+)
synthetase - Bifidobacterium longum
Length = 565
Score = 35.1 bits (77), Expect = 6.4
Identities = 19/92 (20%), Positives = 37/92 (40%)
Query: 170 IGFEICEELWNPQSRHIPLSLDGVEIISNGSGSYMELRKAYVTVDLVKSATFKSGGAYLF 229
IG ICE++W L+ ++++ +GS E K +L + + ++
Sbjct: 149 IGVAICEDIWQDGGPVADLATKNIDLLLTINGSPYEEGKTNTRFELAQRRAAEVNAPVIY 208
Query: 230 SNLRGCDGQRIYFNGCSCVAVNGEIVSRGQQF 261
N G ++ G V +G ++ R F
Sbjct: 209 LNQVGGQDDLVFDGGSFVVDADGTLIERSPMF 240
Score = 34.7 bits (76), Expect = 8.5
Identities = 17/48 (35%), Positives = 25/48 (52%)
Query: 326 LSPEEEISLGPACWLWDYLRRSGQGGFFLPLSGGVDSSSTACIVFSMC 373
L P+EE+ L DY+ ++ G L LSGG+DS+ A + C
Sbjct: 265 LDPDEEVYTACVLGLKDYMAKNHFTGVTLGLSGGIDSALVAAMAADAC 312
>UniRef50_A2GI95 Cluster: Putative uncharacterized protein; n=17;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 139
Score = 35.1 bits (77), Expect = 6.4
Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query: 568 EAPPTAELEPLADGQITQTDEQDMGMTYAEL-SEFGTLRKTYKCGPYSMFEK--LVHKWS 624
E P +E ++G+I QT+E ++ TY +L +E G C PY M+EK L ++
Sbjct: 47 EIPQYIYIELNSEGEILQTEESEIPQTYRDLDNENGYALFWLDC-PYKMYEKKALYEEYR 105
Query: 625 DKCTPKEVAEKVKHFFRCYAINRHKMTVLTPSY 657
C ++ + F YA +H V Y
Sbjct: 106 KYCHENDIRPSSREKF--YAGIKHLFEVRNGKY 136
>UniRef50_Q8VAQ8 Cluster: Wsv343; n=5; Shrimp white spot syndrome
virus|Rep: Wsv343 - White spot syndrome virus (WSSV)
Length = 4180
Score = 34.7 bits (76), Expect = 8.5
Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 14/144 (9%)
Query: 266 VEVTTATIDLEDIRSYRAKNRSRCHLAASNK-PFPRIFVDVSLSDDEDIHLTTNPPIQWH 324
V ++T+T D E++ S K + ++A N F R+ +D +L DE ++N
Sbjct: 3523 VVLSTSTSDCENVLSCLKKRIEKDKMSAKNSGSFIRMCMDKNLLSDEKDDSSSNSSKNTS 3582
Query: 325 YLSPEEEISLGPACWL---WDYLRRSGQGGFFLPLSGGVDSSSTACIVFSMCT----QIC 377
L ++ S A +L + ++S Q F SGG DS+ AC F++ T Q+
Sbjct: 3583 SLPKTDDNSSDIANFLSVFGENRQQSSQFSFASNSSGGGDSNKEAC--FNVDTPKRRQLV 3640
Query: 378 EAIKK----GESQVLYDVRKIMCQ 397
A++K G S ++ ++ K + Q
Sbjct: 3641 SALQKHNSDGSSSIITEIAKAIPQ 3664
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.322 0.136 0.425
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 773,265,016
Number of Sequences: 1657284
Number of extensions: 32092820
Number of successful extensions: 63085
Number of sequences better than 10.0: 110
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 62772
Number of HSP's gapped (non-prelim): 227
length of query: 697
length of database: 575,637,011
effective HSP length: 106
effective length of query: 591
effective length of database: 399,964,907
effective search space: 236379260037
effective search space used: 236379260037
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 76 (34.7 bits)
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