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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001148-TA|BGIBMGA001148-PA|IPR001092|Basic
helix-loop-helix dimerisation region bHLH, IPR011598|Helix-loop-helix
DNA-binding
         (239 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U77629-1|AAB86993.1|  193|Homo sapiens Achaete-Scute homologue 2...    65   2e-10
L08424-1|AAA58376.1|  238|Homo sapiens achaete scute protein pro...    65   2e-10
BC057801-1|AAH57801.2|  193|Homo sapiens achaete-scute complex h...    65   2e-10
BC031299-1|AAH31299.1|  236|Homo sapiens achaete-scute complex h...    65   2e-10
BC004425-1|AAH04425.1|  236|Homo sapiens achaete-scute complex h...    65   2e-10
BC003134-1|AAH03134.1|  236|Homo sapiens achaete-scute complex h...    65   2e-10
BC002341-1|AAH02341.1|  236|Homo sapiens achaete-scute complex h...    65   2e-10
AF442769-2|AAL35362.1|  193|Homo sapiens achaete-scute-like 2 pr...    65   2e-10
S82817-1|AAB39362.1|   68|Homo sapiens ASCL2 protein.                  52   2e-06
BC128212-1|AAI28213.1|  172|Homo sapiens achaete-scute complex h...    44   6e-04
BC128211-1|AAI28212.1|  172|Homo sapiens achaete-scute complex h...    44   6e-04
AY238895-1|AAP69222.1|  172|Homo sapiens achaete-scute-like prot...    44   6e-04
AJ400877-4|CAB92288.1|  181|Homo sapiens ASCL3 protein protein.        43   0.001
AB046450-1|BAB83913.1|  180|Homo sapiens putative bHLH transcrip...    43   0.001
AL139281-3|CAI12668.1|  328|Homo sapiens pancreas specific trans...    36   0.13 
BC002796-1|AAH02796.2|  280|Homo sapiens lymphoblastic leukemia ...    34   0.51 
AF181999-1|AAG09441.1|   48|Homo sapiens bHLH transcription fact...    34   0.51 
AC005546-1|AAC33149.1|  267|Homo sapiens LYL1_HUMAN protein.           34   0.51 
M22638-1|AAA92488.1|  267|Homo sapiens LYL1 protein.                   33   0.88 
M22637-2|AAA88085.1|  267|Homo sapiens LYL1 protein.                   33   0.88 
M22637-1|AAA88084.1|  353|Homo sapiens unknown protein protein.        33   0.88 
BC111413-1|AAI11414.1|  393|Homo sapiens MESP2 protein protein.        31   2.7  
U68723-1|AAB58252.1|  490|Homo sapiens checkpoint suppressor 1 p...    31   3.6  
BC007506-1|AAH07506.1|  468|Homo sapiens checkpoint suppressor 1...    31   3.6  
U08336-1|AAA19969.1|  198|Homo sapiens basic helix-loop-helix tr...    30   6.2  
EF506886-1|ABO43039.1|  199|Homo sapiens transcription factor 15...    30   6.2  
BC113396-1|AAI13397.1|  189|Homo sapiens basic helix-loop-helix ...    30   6.2  
BC113394-1|AAI13395.1|  189|Homo sapiens basic helix-loop-helix ...    30   6.2  
BC067836-1|AAH67836.1|  223|Homo sapiens TCF15 protein protein.        30   6.2  
BC060790-1|AAH60790.1|  440|Homo sapiens suppressor of cytokine ...    30   6.2  
AL133231-1|CAC00470.1|  199|Homo sapiens transcription factor 15...    30   6.2  
AF424815-1|AAL60517.1|  440|Homo sapiens SH2 domain containing S...    30   6.2  
BC032706-1|AAH32706.1|  223|Homo sapiens MGC45491 protein protein.     30   8.2  
BC029071-1|AAH29071.2|  242|Homo sapiens hypothetical protein MG...    30   8.2  

>U77629-1|AAB86993.1|  193|Homo sapiens Achaete-Scute homologue 2
           protein.
          Length = 193

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 54/149 (36%), Positives = 65/149 (43%), Gaps = 17/149 (11%)

Query: 69  TGPQAASIARRNARERNRVKQVNDGFNALRRHLPASXXXXXXXXXXXXXXXXXXXXXDTL 128
           TG  AA++ARRN RERNRVK VN GF ALR+H+P                       +TL
Sbjct: 45  TGGGAAAVARRNERERNRVKLVNLGFQALRQHVP------------HGGASKKLSKVETL 92

Query: 129 RMVVEYIRYLQQLLDESDAA----LGITRDQENRENIPSN-NSVQPMTSIDMDDGFFYGS 183
           R  VEYIR LQ+LL E DA      G  R Q  R + P       P+ +         G 
Sbjct: 93  RSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGR 152

Query: 184 GSPCSEKADSPAPSECSSGVSSAYSAVDR 212
           G      +   A S   SG   A S  +R
Sbjct: 153 GGSSEPGSPRSAYSSDDSGCEGALSPAER 181


>L08424-1|AAA58376.1|  238|Homo sapiens achaete scute protein
           protein.
          Length = 238

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 42/99 (42%), Positives = 54/99 (54%), Gaps = 14/99 (14%)

Query: 51  TPPNLHYRKKVHFRTNPYTGPQA--ASIARRNARERNRVKQVNDGFNALRRHLPASXXXX 108
           +P  +  +++++F    Y+ PQ   A++ARRN RERNRVK VN GF  LR H+P      
Sbjct: 95  SPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVP------ 148

Query: 109 XXXXXXXXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDA 147
                            +TLR  VEYIR LQQLLDE DA
Sbjct: 149 ------NGAANKKMSKVETLRSAVEYIRALQQLLDEHDA 181


>BC057801-1|AAH57801.2|  193|Homo sapiens achaete-scute complex
           homolog 2 (Drosophila) protein.
          Length = 193

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 54/149 (36%), Positives = 65/149 (43%), Gaps = 17/149 (11%)

Query: 69  TGPQAASIARRNARERNRVKQVNDGFNALRRHLPASXXXXXXXXXXXXXXXXXXXXXDTL 128
           TG  AA++ARRN RERNRVK VN GF ALR+H+P                       +TL
Sbjct: 45  TGGGAAAVARRNERERNRVKLVNLGFQALRQHVP------------HGGASKKLSKVETL 92

Query: 129 RMVVEYIRYLQQLLDESDAA----LGITRDQENRENIPSN-NSVQPMTSIDMDDGFFYGS 183
           R  VEYIR LQ+LL E DA      G  R Q  R + P       P+ +         G 
Sbjct: 93  RSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGR 152

Query: 184 GSPCSEKADSPAPSECSSGVSSAYSAVDR 212
           G      +   A S   SG   A S  +R
Sbjct: 153 GGSSEPGSPRSAYSSDDSGCEGALSPAER 181


>BC031299-1|AAH31299.1|  236|Homo sapiens achaete-scute complex
           homolog 1 (Drosophila) protein.
          Length = 236

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 42/99 (42%), Positives = 54/99 (54%), Gaps = 14/99 (14%)

Query: 51  TPPNLHYRKKVHFRTNPYTGPQA--ASIARRNARERNRVKQVNDGFNALRRHLPASXXXX 108
           +P  +  +++++F    Y+ PQ   A++ARRN RERNRVK VN GF  LR H+P      
Sbjct: 93  SPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVP------ 146

Query: 109 XXXXXXXXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDA 147
                            +TLR  VEYIR LQQLLDE DA
Sbjct: 147 ------NGAANKKMSKVETLRSAVEYIRALQQLLDEHDA 179


>BC004425-1|AAH04425.1|  236|Homo sapiens achaete-scute complex
           homolog 1 (Drosophila) protein.
          Length = 236

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 42/99 (42%), Positives = 54/99 (54%), Gaps = 14/99 (14%)

Query: 51  TPPNLHYRKKVHFRTNPYTGPQA--ASIARRNARERNRVKQVNDGFNALRRHLPASXXXX 108
           +P  +  +++++F    Y+ PQ   A++ARRN RERNRVK VN GF  LR H+P      
Sbjct: 93  SPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVP------ 146

Query: 109 XXXXXXXXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDA 147
                            +TLR  VEYIR LQQLLDE DA
Sbjct: 147 ------NGAANKKMSKVETLRSAVEYIRALQQLLDEHDA 179


>BC003134-1|AAH03134.1|  236|Homo sapiens achaete-scute complex
           homolog 1 (Drosophila) protein.
          Length = 236

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 42/99 (42%), Positives = 54/99 (54%), Gaps = 14/99 (14%)

Query: 51  TPPNLHYRKKVHFRTNPYTGPQA--ASIARRNARERNRVKQVNDGFNALRRHLPASXXXX 108
           +P  +  +++++F    Y+ PQ   A++ARRN RERNRVK VN GF  LR H+P      
Sbjct: 93  SPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVP------ 146

Query: 109 XXXXXXXXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDA 147
                            +TLR  VEYIR LQQLLDE DA
Sbjct: 147 ------NGAANKKMSKVETLRSAVEYIRALQQLLDEHDA 179


>BC002341-1|AAH02341.1|  236|Homo sapiens achaete-scute complex
           homolog 1 (Drosophila) protein.
          Length = 236

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 42/99 (42%), Positives = 54/99 (54%), Gaps = 14/99 (14%)

Query: 51  TPPNLHYRKKVHFRTNPYTGPQA--ASIARRNARERNRVKQVNDGFNALRRHLPASXXXX 108
           +P  +  +++++F    Y+ PQ   A++ARRN RERNRVK VN GF  LR H+P      
Sbjct: 93  SPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVP------ 146

Query: 109 XXXXXXXXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDA 147
                            +TLR  VEYIR LQQLLDE DA
Sbjct: 147 ------NGAANKKMSKVETLRSAVEYIRALQQLLDEHDA 179


>AF442769-2|AAL35362.1|  193|Homo sapiens achaete-scute-like 2
           protein.
          Length = 193

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 54/149 (36%), Positives = 65/149 (43%), Gaps = 17/149 (11%)

Query: 69  TGPQAASIARRNARERNRVKQVNDGFNALRRHLPASXXXXXXXXXXXXXXXXXXXXXDTL 128
           TG  AA++ARRN RERNRVK VN GF ALR+H+P                       +TL
Sbjct: 45  TGGGAAAVARRNERERNRVKLVNLGFQALRQHVP------------HGGASKKLSKVETL 92

Query: 129 RMVVEYIRYLQQLLDESDAA----LGITRDQENRENIPSN-NSVQPMTSIDMDDGFFYGS 183
           R  VEYIR LQ+LL E DA      G  R Q  R + P       P+ +         G 
Sbjct: 93  RSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGR 152

Query: 184 GSPCSEKADSPAPSECSSGVSSAYSAVDR 212
           G      +   A S   SG   A S  +R
Sbjct: 153 GGSSEPGSPRSAYSSDDSGCEGALSPAER 181


>S82817-1|AAB39362.1|   68|Homo sapiens ASCL2 protein.
          Length = 68

 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 24/34 (70%), Positives = 28/34 (82%)

Query: 69  TGPQAASIARRNARERNRVKQVNDGFNALRRHLP 102
           TG  AA++ARRN RERNRVK VN GF ALR+H+P
Sbjct: 12  TGGGAAAVARRNERERNRVKLVNLGFQALRQHVP 45


>BC128212-1|AAI28213.1|  172|Homo sapiens achaete-scute complex
           homolog 4 (Drosophila) protein.
          Length = 172

 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 12/72 (16%)

Query: 72  QAASIARRNARERNRVKQVNDGFNALRRHLPASXXXXXXXXXXXXXXXXXXXXXDTLRMV 131
           + A + +RN RER RV+ VN+G+  LR HLP                       +TLR  
Sbjct: 70  EPAFLRKRNERERQRVRCVNEGYARLRDHLPRE------------LADKRLSKVETLRAA 117

Query: 132 VEYIRYLQQLLD 143
           ++YI++LQ+LL+
Sbjct: 118 IDYIKHLQELLE 129


>BC128211-1|AAI28212.1|  172|Homo sapiens achaete-scute complex
           homolog 4 (Drosophila) protein.
          Length = 172

 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 12/72 (16%)

Query: 72  QAASIARRNARERNRVKQVNDGFNALRRHLPASXXXXXXXXXXXXXXXXXXXXXDTLRMV 131
           + A + +RN RER RV+ VN+G+  LR HLP                       +TLR  
Sbjct: 70  EPAFLRKRNERERQRVRCVNEGYARLRDHLPRE------------LADKRLSKVETLRAA 117

Query: 132 VEYIRYLQQLLD 143
           ++YI++LQ+LL+
Sbjct: 118 IDYIKHLQELLE 129


>AY238895-1|AAP69222.1|  172|Homo sapiens achaete-scute-like protein
           4 protein.
          Length = 172

 Score = 43.6 bits (98), Expect = 6e-04
 Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 12/72 (16%)

Query: 72  QAASIARRNARERNRVKQVNDGFNALRRHLPASXXXXXXXXXXXXXXXXXXXXXDTLRMV 131
           + A + +RN RER RV+ VN+G+  LR HLP                       +TLR  
Sbjct: 70  EPAFLRKRNERERQRVRCVNEGYARLRDHLPRE------------LADKRLSKVETLRAA 117

Query: 132 VEYIRYLQQLLD 143
           ++YI++LQ+LL+
Sbjct: 118 IDYIKHLQELLE 129


>AJ400877-4|CAB92288.1|  181|Homo sapiens ASCL3 protein protein.
          Length = 181

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/65 (40%), Positives = 32/65 (49%), Gaps = 12/65 (18%)

Query: 78  RRNARERNRVKQVNDGFNALRRHLPASXXXXXXXXXXXXXXXXXXXXXDTLRMVVEYIRY 137
           +RN RER RVK VN+G+  LR HLP                       +TLR  ++YI Y
Sbjct: 97  KRNERERQRVKCVNEGYAQLRHHLPEE------------YLEKRLSKVETLRAAIKYINY 144

Query: 138 LQQLL 142
           LQ LL
Sbjct: 145 LQSLL 149


>AB046450-1|BAB83913.1|  180|Homo sapiens putative bHLH
           transcription factor protein.
          Length = 180

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 26/65 (40%), Positives = 32/65 (49%), Gaps = 12/65 (18%)

Query: 78  RRNARERNRVKQVNDGFNALRRHLPASXXXXXXXXXXXXXXXXXXXXXDTLRMVVEYIRY 137
           +RN RER RVK VN+G+  LR HLP                       +TLR  ++YI Y
Sbjct: 96  KRNERERQRVKCVNEGYAQLRHHLPEE------------YLEKRLSKVETLRAAIKYINY 143

Query: 138 LQQLL 142
           LQ LL
Sbjct: 144 LQSLL 148


>AL139281-3|CAI12668.1|  328|Homo sapiens pancreas specific
           transcription factor, 1a protein.
          Length = 328

 Score = 35.9 bits (79), Expect = 0.13
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 12/63 (19%)

Query: 80  NARERNRVKQVNDGFNALRRHLPASXXXXXXXXXXXXXXXXXXXXXDTLRMVVEYIRYLQ 139
           N RER R++ +ND F  LR H+P                       DTLR+ + YI +L 
Sbjct: 169 NVRERRRMQSINDAFEGLRSHIP------------TLPYEKRLSKVDTLRLAIGYINFLS 216

Query: 140 QLL 142
           +L+
Sbjct: 217 ELV 219


>BC002796-1|AAH02796.2|  280|Homo sapiens lymphoblastic leukemia
           derived sequence 1 protein.
          Length = 280

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 42/143 (29%), Positives = 58/143 (40%), Gaps = 24/143 (16%)

Query: 58  RKKVHFRTNPYTGPQAASIARR---NARERNRVKQVNDGFNALRRHLPASXXXXXXXXXX 114
           R+  H   +   G Q   +ARR   N+RER R + VN  F  LR+ LP            
Sbjct: 131 RRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLP------------ 178

Query: 115 XXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDAALGITRDQENRENIPSNNSVQPMTSID 174
                      + LR+ ++YI +L +LL +  AAL            P     +P+  + 
Sbjct: 179 THPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALA-------AGPTPPGPRKRPVHRVP 231

Query: 175 MDDGFFYGSGSPCSEKADS-PAP 196
            DDG   GSG      A S PAP
Sbjct: 232 -DDGARRGSGRRAEAAARSQPAP 253


>AF181999-1|AAG09441.1|   48|Homo sapiens bHLH transcription factor
           p48 protein.
          Length = 48

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 12/23 (52%), Positives = 16/23 (69%)

Query: 80  NARERNRVKQVNDGFNALRRHLP 102
           N RER R++ +ND F  LR H+P
Sbjct: 2   NVRERRRMQSINDAFEGLRSHIP 24


>AC005546-1|AAC33149.1|  267|Homo sapiens LYL1_HUMAN protein.
          Length = 267

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 42/143 (29%), Positives = 58/143 (40%), Gaps = 24/143 (16%)

Query: 58  RKKVHFRTNPYTGPQAASIARR---NARERNRVKQVNDGFNALRRHLPASXXXXXXXXXX 114
           R+  H   +   G Q   +ARR   N+RER R + VN  F  LR+ LP            
Sbjct: 118 RRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLP------------ 165

Query: 115 XXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDAALGITRDQENRENIPSNNSVQPMTSID 174
                      + LR+ ++YI +L +LL +  AAL            P     +P+  + 
Sbjct: 166 THPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALA-------AGPTPPGPRKRPVHRVP 218

Query: 175 MDDGFFYGSGSPCSEKADS-PAP 196
            DDG   GSG      A S PAP
Sbjct: 219 -DDGARRGSGRRAEAAARSQPAP 240


>M22638-1|AAA92488.1|  267|Homo sapiens LYL1 protein.
          Length = 267

 Score = 33.1 bits (72), Expect = 0.88
 Identities = 42/143 (29%), Positives = 58/143 (40%), Gaps = 24/143 (16%)

Query: 58  RKKVHFRTNPYTGPQAASIARR---NARERNRVKQVNDGFNALRRHLPASXXXXXXXXXX 114
           R+  H   +   G Q   +ARR   N+RER R + VN  F  LR+ LP            
Sbjct: 118 RRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLP------------ 165

Query: 115 XXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDAALGITRDQENRENIPSNNSVQPMTSID 174
                      + LR+ ++YI +L +LL +  AAL            P     +P+  + 
Sbjct: 166 THPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALA-------AGPTPPGPRKRPVHRVP 218

Query: 175 MDDGFFYGSGSPCSEKADS-PAP 196
            DDG   GSG      A S PAP
Sbjct: 219 -DDGPRRGSGRRAEAAARSQPAP 240


>M22637-2|AAA88085.1|  267|Homo sapiens LYL1 protein.
          Length = 267

 Score = 33.1 bits (72), Expect = 0.88
 Identities = 42/143 (29%), Positives = 58/143 (40%), Gaps = 24/143 (16%)

Query: 58  RKKVHFRTNPYTGPQAASIARR---NARERNRVKQVNDGFNALRRHLPASXXXXXXXXXX 114
           R+  H   +   G Q   +ARR   N+RER R + VN  F  LR+ LP            
Sbjct: 118 RRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLP------------ 165

Query: 115 XXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDAALGITRDQENRENIPSNNSVQPMTSID 174
                      + LR+ ++YI +L +LL +  AAL            P     +P+  + 
Sbjct: 166 THPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALA-------AGPTPPGPRKRPVHRVP 218

Query: 175 MDDGFFYGSGSPCSEKADS-PAP 196
            DDG   GSG      A S PAP
Sbjct: 219 -DDGPRRGSGRRAEAAARSQPAP 240


>M22637-1|AAA88084.1|  353|Homo sapiens unknown protein protein.
          Length = 353

 Score = 33.1 bits (72), Expect = 0.88
 Identities = 42/143 (29%), Positives = 58/143 (40%), Gaps = 24/143 (16%)

Query: 58  RKKVHFRTNPYTGPQAASIARR---NARERNRVKQVNDGFNALRRHLPASXXXXXXXXXX 114
           R+  H   +   G Q   +ARR   N+RER R + VN  F  LR+ LP            
Sbjct: 204 RRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLP------------ 251

Query: 115 XXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDAALGITRDQENRENIPSNNSVQPMTSID 174
                      + LR+ ++YI +L +LL +  AAL            P     +P+  + 
Sbjct: 252 THPPDRKLSKNEVLRLAMKYIGFLVRLLRDQAAALA-------AGPTPPGPRKRPVHRVP 304

Query: 175 MDDGFFYGSGSPCSEKADS-PAP 196
            DDG   GSG      A S PAP
Sbjct: 305 -DDGPRRGSGRRAEAAARSQPAP 326


>BC111413-1|AAI11414.1|  393|Homo sapiens MESP2 protein protein.
          Length = 393

 Score = 31.5 bits (68), Expect = 2.7
 Identities = 29/114 (25%), Positives = 43/114 (37%), Gaps = 13/114 (11%)

Query: 52  PPNLHYRKKVHFRTNPY---TGPQAASIARRNARERNRVKQVNDGFNALRRHLPASXXXX 108
           PP+   R      T P    TGP        + RE+ R++ +    + LRR LP S    
Sbjct: 56  PPSCSSRAAEAAATTPRRARTGPAGGQRQSASEREKLRMRTLARALHELRRFLPPSLAPA 115

Query: 109 XXXXXXXXXXXXXXXXXDTLRMVVEYIRYLQQLLDESDAALGITRDQENRENIP 162
                            +TLR+ + YI +L  +L  S+ +L   R Q      P
Sbjct: 116 GQSLTKI----------ETLRLAIRYIGHLSAVLGLSEESLQCRRRQRGDAGSP 159


>U68723-1|AAB58252.1|  490|Homo sapiens checkpoint suppressor 1
           protein.
          Length = 490

 Score = 31.1 bits (67), Expect = 3.6
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 6/79 (7%)

Query: 150 GITRDQENRENIPSNNSVQPMTSIDMDDGFFYGSGSPCSEKADSPAPSECSSGVSSAYSA 209
           GIT  +   E+ PS  S  P+ S D  +   Y S    + ++ SP     S   SS+ SA
Sbjct: 308 GITSCRMRTESEPSCGS--PVVSGDPKEDHNYSSAKSSNARSTSPTSDSIS---SSSSSA 362

Query: 210 VDRYEVTTQ-QQMGSMDEE 227
            D YE  T+  Q GS   E
Sbjct: 363 DDHYEFATKGSQEGSEGSE 381


>BC007506-1|AAH07506.1|  468|Homo sapiens checkpoint suppressor 1
           protein.
          Length = 468

 Score = 31.1 bits (67), Expect = 3.6
 Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 6/79 (7%)

Query: 150 GITRDQENRENIPSNNSVQPMTSIDMDDGFFYGSGSPCSEKADSPAPSECSSGVSSAYSA 209
           GIT  +   E+ PS  S  P+ S D  +   Y S    + ++ SP     S   SS+ SA
Sbjct: 286 GITSCRMRTESEPSCGS--PVVSGDPKEDHNYSSAKSSNARSTSPTSDSIS---SSSSSA 340

Query: 210 VDRYEVTTQ-QQMGSMDEE 227
            D YE  T+  Q GS   E
Sbjct: 341 DDHYEFATKGSQEGSEGSE 359


>U08336-1|AAA19969.1|  198|Homo sapiens basic helix-loop-helix
           transcription factor protein.
          Length = 198

 Score = 30.3 bits (65), Expect = 6.2
 Identities = 13/23 (56%), Positives = 16/23 (69%)

Query: 80  NARERNRVKQVNDGFNALRRHLP 102
           NARER+R + VN  F ALR  +P
Sbjct: 78  NARERDRTQSVNTAFTALRTLIP 100


>EF506886-1|ABO43039.1|  199|Homo sapiens transcription factor 15
           (basic helix-loop-helix) protein.
          Length = 199

 Score = 30.3 bits (65), Expect = 6.2
 Identities = 13/23 (56%), Positives = 16/23 (69%)

Query: 80  NARERNRVKQVNDGFNALRRHLP 102
           NARER+R + VN  F ALR  +P
Sbjct: 78  NARERDRTQSVNTAFTALRTLIP 100


>BC113396-1|AAI13397.1|  189|Homo sapiens basic helix-loop-helix
           domain containing, class B, 8 protein.
          Length = 189

 Score = 30.3 bits (65), Expect = 6.2
 Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 3/36 (8%)

Query: 70  GPQAASIARR---NARERNRVKQVNDGFNALRRHLP 102
           G + +SI RR   N RER R+ ++N+ F ALR  +P
Sbjct: 68  GRRDSSIQRRLESNERERQRMHKLNNAFQALREVIP 103


>BC113394-1|AAI13395.1|  189|Homo sapiens basic helix-loop-helix
           domain containing, class B, 8 protein.
          Length = 189

 Score = 30.3 bits (65), Expect = 6.2
 Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 3/36 (8%)

Query: 70  GPQAASIARR---NARERNRVKQVNDGFNALRRHLP 102
           G + +SI RR   N RER R+ ++N+ F ALR  +P
Sbjct: 68  GRRDSSIQRRLESNERERQRMHKLNNAFQALREVIP 103


>BC067836-1|AAH67836.1|  223|Homo sapiens TCF15 protein protein.
          Length = 223

 Score = 30.3 bits (65), Expect = 6.2
 Identities = 13/23 (56%), Positives = 16/23 (69%)

Query: 80  NARERNRVKQVNDGFNALRRHLP 102
           NARER+R + VN  F ALR  +P
Sbjct: 102 NARERDRTQSVNTAFTALRTLIP 124


>BC060790-1|AAH60790.1|  440|Homo sapiens suppressor of cytokine
           signaling 4 protein.
          Length = 440

 Score = 30.3 bits (65), Expect = 6.2
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 5/53 (9%)

Query: 156 ENRENIPSNNSVQPMT----SIDMDDGFFY-GSGSPCSEKADSPAPSECSSGV 203
           EN ENI  N  V+P T    S D  DG+ + G     S+K++S + +E  +G+
Sbjct: 3   ENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGI 55


>AL133231-1|CAC00470.1|  199|Homo sapiens transcription factor 15
           (basic helix-loop-helix) protein.
          Length = 199

 Score = 30.3 bits (65), Expect = 6.2
 Identities = 13/23 (56%), Positives = 16/23 (69%)

Query: 80  NARERNRVKQVNDGFNALRRHLP 102
           NARER+R + VN  F ALR  +P
Sbjct: 78  NARERDRTQSVNTAFTALRTLIP 100


>AF424815-1|AAL60517.1|  440|Homo sapiens SH2 domain containing SOCS
           box protein SOCS4 protein.
          Length = 440

 Score = 30.3 bits (65), Expect = 6.2
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 5/53 (9%)

Query: 156 ENRENIPSNNSVQPMT----SIDMDDGFFY-GSGSPCSEKADSPAPSECSSGV 203
           EN ENI  N  V+P T    S D  DG+ + G     S+K++S + +E  +G+
Sbjct: 3   ENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGI 55


>BC032706-1|AAH32706.1|  223|Homo sapiens MGC45491 protein protein.
          Length = 223

 Score = 29.9 bits (64), Expect = 8.2
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 10  GQTNYVVVSSGYPSNTLNKSSLEKRNVAIAPAPEKNYVTHDTPPNLHYRKKVHFRTNPYT 69
           G+T+  V+ +G  S +  K+S  K  V +  +  +    H   P   +RK VH RT   T
Sbjct: 27  GKTS-AVLKAGRQSVSGRKNSTSKDLVTLGASSLREERGHPLHPR--HRKAVHLRTRGRT 83

Query: 70  GPQAASIARRNARERNRVKQ 89
                ++AR + R R  V++
Sbjct: 84  RGWVQTLARMSRRTRGPVER 103


>BC029071-1|AAH29071.2|  242|Homo sapiens hypothetical protein
           MGC45491 protein.
          Length = 242

 Score = 29.9 bits (64), Expect = 8.2
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 3/80 (3%)

Query: 10  GQTNYVVVSSGYPSNTLNKSSLEKRNVAIAPAPEKNYVTHDTPPNLHYRKKVHFRTNPYT 69
           G+T+  V+ +G  S +  K+S  K  V +  +  +    H   P   +RK VH RT   T
Sbjct: 47  GKTS-AVLKAGRQSVSGRKNSTSKDLVTLGASSLREERGHPLHPR--HRKAVHLRTRGRT 103

Query: 70  GPQAASIARRNARERNRVKQ 89
                ++AR + R R  V++
Sbjct: 104 RGWVQTLARMSRRTRGPVER 123


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.312    0.127    0.364 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 33,464,499
Number of Sequences: 224733
Number of extensions: 1364263
Number of successful extensions: 3229
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 3189
Number of HSP's gapped (non-prelim): 53
length of query: 239
length of database: 73,234,838
effective HSP length: 88
effective length of query: 151
effective length of database: 53,458,334
effective search space: 8072208434
effective search space used: 8072208434
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 64 (29.9 bits)

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