BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001138-TA|BGIBMGA001138- PA|IPR005135|Endonuclease/exonuclease/phosphatase (404 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000DB7E14 Cluster: PREDICTED: similar to CG12034-PA... 324 2e-87 UniRef50_UPI0000D55DE6 Cluster: PREDICTED: similar to CG12034-PA... 306 7e-82 UniRef50_Q17JK7 Cluster: Neutral Sphingomyelinase, putative; n=1... 302 9e-81 UniRef50_Q9VZS6 Cluster: Putative neutral sphingomyelinase; n=2;... 239 7e-62 UniRef50_A7RL32 Cluster: Predicted protein; n=2; Nematostella ve... 213 7e-54 UniRef50_UPI000069E344 Cluster: Sphingomyelin phosphodiesterase ... 203 6e-51 UniRef50_O45870 Cluster: Putative neutral sphingomyelinase; n=2;... 201 2e-50 UniRef50_O60906 Cluster: Sphingomyelin phosphodiesterase 2; n=17... 199 1e-49 UniRef50_Q4LEU0 Cluster: Mg2+-dependent neutral sphingomyelinase... 198 3e-49 UniRef50_UPI0000E490B9 Cluster: PREDICTED: similar to LD24865p; ... 168 3e-40 UniRef50_A7S570 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 154 3e-36 UniRef50_Q5D9I7 Cluster: SJCHGC06222 protein; n=1; Schistosoma j... 149 1e-34 UniRef50_O74369 Cluster: Putative neutral sphingomyelinase; n=3;... 139 1e-31 UniRef50_A4QVL4 Cluster: Putative uncharacterized protein; n=1; ... 134 3e-30 UniRef50_Q6C8M5 Cluster: Yarrowia lipolytica chromosome D of str... 134 4e-30 UniRef50_A1CTA2 Cluster: Sphingomyelinase family protein, putati... 133 7e-30 UniRef50_Q2UM93 Cluster: Sphingomyelinase family protein; n=3; T... 133 9e-30 UniRef50_P40015 Cluster: Inositol phosphosphingolipids phospholi... 132 2e-29 UniRef50_Q4PAL6 Cluster: Putative uncharacterized protein; n=1; ... 125 2e-27 UniRef50_A3LY15 Cluster: Phospholipase C type enzyme; n=5; Sacch... 124 3e-27 UniRef50_Q2HD33 Cluster: Putative uncharacterized protein; n=2; ... 121 4e-26 UniRef50_Q1HG89 Cluster: Inositol phosphorylsphingolipid-phospho... 115 3e-24 UniRef50_A5DP62 Cluster: Putative uncharacterized protein; n=1; ... 110 7e-23 UniRef50_Q4DIM2 Cluster: Putative uncharacterized protein; n=1; ... 93 2e-17 UniRef50_Q4QIE9 Cluster: Putative uncharacterized protein; n=3; ... 90 1e-16 UniRef50_Q57U95 Cluster: Sphingomyelin phosphodiesterase, putati... 82 2e-14 UniRef50_UPI000023DADB Cluster: hypothetical protein FG01057.1; ... 55 4e-06 UniRef50_Q5TEC8 Cluster: Sphingomyelin phosphodiesterase 2, neut... 47 0.001 UniRef50_A0DMK4 Cluster: Chromosome undetermined scaffold_56, wh... 42 0.022 UniRef50_UPI0000F21D16 Cluster: PREDICTED: similar to Mg2+-depen... 42 0.029 UniRef50_Q9NY59 Cluster: Sphingomyelin phosphodiesterase 3; n=22... 41 0.051 UniRef50_Q2SCA2 Cluster: Endonuclease/exonuclease/phophatase fam... 41 0.067 UniRef50_P17627 Cluster: Sphingomyelinase C precursor; n=5; Lept... 40 0.089 UniRef50_A3Y6R9 Cluster: Putative uncharacterized protein; n=1; ... 38 0.36 UniRef50_Q93HR5 Cluster: Sphingomyelinase; n=2; cellular organis... 37 1.1 UniRef50_A2QPH4 Cluster: Transposase Tan1-Aspergillus niger; n=3... 36 1.4 UniRef50_Q5KM82 Cluster: Trehalose-phosphatase, putative; n=2; F... 36 1.9 UniRef50_A1A5I2 Cluster: Zgc:154063; n=2; Danio rerio|Rep: Zgc:1... 36 2.5 UniRef50_A0DEC1 Cluster: Chromosome undetermined scaffold_48, wh... 36 2.5 UniRef50_Q8CVD9 Cluster: Sphingomyelinase C; n=5; Leptospira int... 35 3.3 UniRef50_Q5AVC8 Cluster: Ferrochelatase; n=9; Fungi/Metazoa grou... 35 3.3 UniRef50_A7F024 Cluster: Predicted protein; n=1; Sclerotinia scl... 35 3.3 UniRef50_P59116 Cluster: Sphingomyelinase C 2 precursor; n=6; Le... 35 3.3 UniRef50_O51552 Cluster: Rep helicase, single-stranded DNA-depen... 35 4.4 UniRef50_Q9N467 Cluster: Putative uncharacterized protein; n=2; ... 35 4.4 UniRef50_Q4UHF9 Cluster: Putative uncharacterized protein; n=2; ... 35 4.4 UniRef50_A7AR39 Cluster: Endonuclease/exonuclease/phosphatase fa... 35 4.4 UniRef50_P22657 Cluster: RNA replication protein (152 kDa protei... 35 4.4 UniRef50_UPI00006CF82F Cluster: Endonuclease/Exonuclease/phospha... 34 5.8 UniRef50_A6F7A0 Cluster: Putative phospholipase C; n=1; Moritell... 34 5.8 UniRef50_A5ID83 Cluster: Putative uncharacterized protein; n=4; ... 34 5.8 UniRef50_A4M652 Cluster: DegV family protein; n=1; Petrotoga mob... 34 5.8 UniRef50_Q332A8 Cluster: Conserved hypothetical phage-related pr... 34 5.8 UniRef50_Q7QTT1 Cluster: GLP_191_17261_17716; n=1; Giardia lambl... 34 5.8 UniRef50_Q8YVZ6 Cluster: All1820 protein; n=2; Nostocaceae|Rep: ... 34 7.7 UniRef50_A6CBS1 Cluster: Probable aggregation factor core protei... 34 7.7 UniRef50_O96266 Cluster: Putative uncharacterized protein PFB087... 34 7.7 UniRef50_A6R9W9 Cluster: Predicted protein; n=1; Ajellomyces cap... 34 7.7 >UniRef50_UPI0000DB7E14 Cluster: PREDICTED: similar to CG12034-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG12034-PA - Apis mellifera Length = 385 Score = 324 bits (797), Expect = 2e-87 Identities = 162/397 (40%), Positives = 239/397 (60%), Gaps = 30/397 (7%) Query: 2 IINLMLL-LRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVL 60 +IN++ L GIP VS N+ R AI+ ++I+CLQE+WS D+ +K + L Sbjct: 6 LINILTLNCWGIPYVSPNRSARMTAIADKFATENYDIICLQEIWSINDFKMIKAKTQEQL 65 Query: 61 PYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGE 120 PYS+YFYSGV+GSGLC+ SK+ I+DV FH+WPLNGY+HKIHHGDWFGGKGVGLC+++ Sbjct: 66 PYSHYFYSGVIGSGLCILSKFPIKDVIFHKWPLNGYVHKIHHGDWFGGKGVGLCKLQIHN 125 Query: 121 RLINVYCTHLHAEYH-EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLS 179 +NVY HLHAEY+ +D Y+AHRVLQA+ TA+F+++TS AD +IL GDLNT P DL Sbjct: 126 WNVNVYIAHLHAEYNRHNDEYIAHRVLQAFDTAQFIRMTSGGADSTILGGDLNTEPQDLV 185 Query: 180 YKIISQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFH 239 Y+II + L D + + GT++ NNSY++ K +P+GKRIDHIL+ Sbjct: 186 YRIICGVAGLTDACSNS--------SSNLGTNECANNSYTNTKHANTFPDGKRIDHILYQ 237 Query: 240 TNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESVDSAFQET 299 + + ++NF +P P+R+P + FSYSDH A+ S+D +++ Sbjct: 238 GTKNVKIEIINFQHPFPNRIPYKNFSYSDHEAIMATFKF------------SID--IKDS 283 Query: 300 ITQAIKVCRDATTNXXXXXXXXXXXXXXIFMFLLGSVGFWPNFLIYDVL------KLLIT 353 + +AI +C + N + + L+ S+G +F DV+ ++ +T Sbjct: 284 LKEAINICETSLKNVRRQRFWYLLLGCILIIPLIWSIGLDCSFTSLDVIIGLNIGRIFLT 343 Query: 354 ALCFYNLVMGSLWNQIEMNSLKAGLNALENFIQTRND 390 A+ Y L M S+WN +E N+LKA +E ++ N+ Sbjct: 344 AILCYTLFMSSIWNSVEKNALKAACLGMEICLRNLNN 380 >UniRef50_UPI0000D55DE6 Cluster: PREDICTED: similar to CG12034-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG12034-PA - Tribolium castaneum Length = 362 Score = 306 bits (751), Expect = 7e-82 Identities = 143/323 (44%), Positives = 209/323 (64%), Gaps = 10/323 (3%) Query: 11 GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70 G+ VVSKN++ R +AI+ L S++++VCLQE+W + DY ++ + VLPYS+YFYSGV Sbjct: 12 GLAVVSKNRRHRMQAIAEKLATSQYDVVCLQEIWLDSDYQLIRNKVSGVLPYSHYFYSGV 71 Query: 71 LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130 GSG+C+ S+ ++DVFFHQWP+NGYIHKIHHGDWFGGKGVGLC++K +NVY HL Sbjct: 72 TGSGVCILSRHPMEDVFFHQWPVNGYIHKIHHGDWFGGKGVGLCKLKVNNYTVNVYSAHL 131 Query: 131 HAEYHED-DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSL 189 HAEY + D Y AHRVLQ++ TA+F+++TS AD+ +LAGDLNT PGDL+Y+I+ +P L Sbjct: 132 HAEYDRNCDEYQAHRVLQSFDTAQFIQMTSGDADLVVLAGDLNTEPGDLAYRIMLSVPGL 191 Query: 190 LDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEARVV 249 +D + E +A T+++L NSY+ +K GKRID+I++H S + + Sbjct: 192 VDAFGEAGETVQNCVA----TNESLTNSYTPVALLKKNIPGKRIDYIMYHPGSSLQIDLK 247 Query: 250 NFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESVDSAFQETI-TQAIKVCR 308 ++ PLP ++P +SYSDH A++ L + K R D ++T+ ++I++C Sbjct: 248 SYTLPLPHKIPGCAYSYSDHEAIAATLIV----TKSEIRSLKSDQHMKKTVLEESIEICD 303 Query: 309 DATTNXXXXXXXXXXXXXXIFMF 331 DA +FMF Sbjct: 304 DALRGLNNHKYLYWFFTITLFMF 326 >UniRef50_Q17JK7 Cluster: Neutral Sphingomyelinase, putative; n=1; Aedes aegypti|Rep: Neutral Sphingomyelinase, putative - Aedes aegypti (Yellowfever mosquito) Length = 420 Score = 302 bits (742), Expect = 9e-81 Identities = 157/395 (39%), Positives = 230/395 (58%), Gaps = 22/395 (5%) Query: 5 LMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 64 L L + GIP VSK++ R EAI L ++IV LQEVWS+ DY YLK+ ++ VLP+++ Sbjct: 8 LTLNIWGIPYVSKDRAVRVEAIGDVLSSGNYDIVSLQEVWSDSDYQYLKKRVEGVLPFAH 67 Query: 65 YFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLIN 124 YFYSGV+GSGL + S++ I FH W +NGY+H+I HGDWFGGKGVGL +I ++L+N Sbjct: 68 YFYSGVVGSGLALLSRYPIVSALFHAWSVNGYVHRIQHGDWFGGKGVGLAKIAVNDQLVN 127 Query: 125 VYCTHLHAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKII 183 VY HLHAEY + D Y+AHRV+QAY TA+F++ T A + ILAGDLNT PGDL+Y+++ Sbjct: 128 VYAAHLHAEYDRKCDDYMAHRVIQAYDTAQFIESTRGNAVMQILAGDLNTEPGDLAYRVL 187 Query: 184 SQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHS 243 L+D + K L GT++ NSY+DP+ K YP+GKRID+I++ Sbjct: 188 QTNAKLIDTADKKLYAAGHL-----GTNEIGRNSYTDPETGKKYPQGKRIDYIMYRIGEH 242 Query: 244 WEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQR----------QESVD 293 +E R++ PLPDR+P + SYSDH AV ++ LK Q+ D Sbjct: 243 FEGRLLEHRLPLPDRIPGKDISYSDHEAVYAKIILKKTNSSTIQQLMACGSGEGSHGKCD 302 Query: 294 SAFQETI---TQAIKVCRDATTNXXXXXXXXXXXXXXIFMFLLGSVGFWPNFLI---YDV 347 QETI ++I +C ++ + + LL + + + Y + Sbjct: 303 YNDQETILALRESIVICNESLKQLDSHKRSYTLMAIGVIIVLLNMLELEAPYGLKSAYLL 362 Query: 348 LKLLITALCFYNLVMGSLWNQIEMNSLKAGLNALE 382 LK L+ + + M ++WN +E + + AG ++E Sbjct: 363 LKFLLCGFVIFFIFMATIWNVMEKHGILAGKLSME 397 >UniRef50_Q9VZS6 Cluster: Putative neutral sphingomyelinase; n=2; Sophophora|Rep: Putative neutral sphingomyelinase - Drosophila melanogaster (Fruit fly) Length = 442 Score = 239 bits (586), Expect = 7e-62 Identities = 118/290 (40%), Positives = 179/290 (61%), Gaps = 11/290 (3%) Query: 5 LMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 64 L L + GIP VS +++ R +AI L +++IV LQEVW+++D L++ + VLP+S+ Sbjct: 9 LTLNIWGIPYVSSDRRPRIDAICKELASGKYDIVSLQEVWAQEDSELLQKGTEAVLPHSH 68 Query: 65 YFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLIN 124 YF+SGV+G+GL V SK+ I FH W +NGY H+I H DWFGGKGVGLCRI G ++++ Sbjct: 69 YFHSGVMGAGLLVLSKYPILGTLFHAWSVNGYFHRIQHADWFGGKGVGLCRILVGGQMVH 128 Query: 125 VYCTHLHAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKII 183 +Y HLHAEY + +D Y HRV+QA+ TA+F++ T + + ILAGDLN P D+SYK++ Sbjct: 129 LYNAHLHAEYDNANDEYKTHRVIQAFDTAQFIEATRGNSALQILAGDLNAQPQDISYKVL 188 Query: 184 SQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHS 243 +LD + + + T++ +NSY+ + + P G RIDHI Sbjct: 189 LYTSKMLDSCD----------SDSFRTNECEHNSYTSKQARERNPLGIRIDHIFVRGGDH 238 Query: 244 WEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESVD 293 A + + P P+RVP ++FS+SDH AV +L L E + + +++ Sbjct: 239 VNAEIAEYKLPFPERVPGEKFSFSDHEAVMAKLKLFKLEPRSEEPVATIE 288 >UniRef50_A7RL32 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 419 Score = 213 bits (520), Expect = 7e-54 Identities = 113/285 (39%), Positives = 172/285 (60%), Gaps = 9/285 (3%) Query: 11 GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70 GIP +SK KER+E I+ L ++++V LQEVW++ DY + + L + LPYS YFYSGV Sbjct: 23 GIPFISKQVKERFEHIAKELSTGKYDVVALQEVWNKSDYAVMCDKLSSTLPYSLYFYSGV 82 Query: 71 LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130 +GSG+CVFS++ I + F +++ LNGY++K+ HGDW G G C I + I+ + +HL Sbjct: 83 IGSGMCVFSRYRITNSFTYRFSLNGYLYKLWHGDWLAGTSAGYCVIDHPIKPIHFFVSHL 142 Query: 131 HAEYH-EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSL 189 HAEY+ +DD YLAHRV QAY A+ ++L + P+D I+ GD+N+ P DL Y+I+ LP L Sbjct: 143 HAEYNRQDDEYLAHRVTQAYQFAQLIELITKPSDCVIVCGDMNSEPTDLCYRILCNLPGL 202 Query: 190 LDPY-NMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYP-EGKRIDHILFHTNHSWEAR 247 D + EG + G S N + + ++ P +G RID+I + + S Sbjct: 203 TDTWLECNKEGYH---GNTYGVSHNSFAGSTFQQAIQKGPSDGIRIDYIFYRGDRS-NME 258 Query: 248 VVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESV 292 +++ + R+P ++ SYSDH V LK ++ L + QE V Sbjct: 259 LLDC-HVTMSRIPWEEISYSDHEGVLATFCLKN-DKVLEKGQEKV 301 >UniRef50_UPI000069E344 Cluster: Sphingomyelin phosphodiesterase 2 (EC 3.1.4.12) (Neutral sphingomyelinase) (nSMase) (N-SMase) (Lyso-platelet-activating factor- phospholipase C) (Lyso-PAF-PLC).; n=2; Xenopus tropicalis|Rep: Sphingomyelin phosphodiesterase 2 (EC 3.1.4.12) (Neutral sphingomyelinase) (nSMase) (N-SMase) (Lyso-platelet-activating factor- phospholipase C) (Lyso-PAF-PLC). - Xenopus tropicalis Length = 341 Score = 203 bits (496), Expect = 6e-51 Identities = 99/225 (44%), Positives = 149/225 (66%), Gaps = 5/225 (2%) Query: 15 VSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGVLGSG 74 +SK +KER I L + +++ LQE+WS+KDY L+ L +V PY++ F SGV+GSG Sbjct: 22 LSKKRKERLALIGQLLSQQCYDLALLQEIWSDKDYSELRHRLSDVFPYTHRFKSGVIGSG 81 Query: 75 LCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHLHAEY 134 LCVFS++ I D +Q+ LNG+ + ++HGDWF GK VGL ++K L +VY THLHAEY Sbjct: 82 LCVFSQFPIIDCLQYQFSLNGFPYMMNHGDWFCGKAVGLVKLKAYGFLCHVYVTHLHAEY 141 Query: 135 -HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPY 193 E+D Y +HR+LQ++ A+F++ TS+ +DV +LAGDLN PGDL K++ + L D Y Sbjct: 142 CRENDCYRSHRILQSWELAQFIRHTSNNSDVVVLAGDLNMHPGDLGVKLVREWTGLKDSY 201 Query: 194 NMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILF 238 E P G + +N ++DP+++K +P+G RID+I++ Sbjct: 202 LECTEYEGP----PDGCTLIPSNPFTDPQELKNFPQGIRIDYIMY 242 >UniRef50_O45870 Cluster: Putative neutral sphingomyelinase; n=2; Caenorhabditis|Rep: Putative neutral sphingomyelinase - Caenorhabditis elegans Length = 434 Score = 201 bits (491), Expect = 2e-50 Identities = 126/395 (31%), Positives = 203/395 (51%), Gaps = 18/395 (4%) Query: 3 INLMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPY 62 +N L + P+ S ++ R I Y++ ++IV LQE+WS D++ L E + +V PY Sbjct: 44 LNAWCLPQPWPIGSTDRVHRLNKIGQYMIDELYDIVGLQELWSYYDFVRLSEQVSSVYPY 103 Query: 63 SYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF-GER 121 +YF+SG GSG+CVFS+ I +++ LNG+ H IH GDWFGGK VGL I+ G+ Sbjct: 104 FHYFHSGFTGSGVCVFSRHPIVSTLTNRYSLNGFAHHIHRGDWFGGKVVGLTEIEIDGDL 163 Query: 122 LINVYCTHLHAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSY 180 +N Y THLHAEY E+D+YL HR QA+ A+FV+ T+ ADV I+ GDLN P DL + Sbjct: 164 RVNFYTTHLHAEYDRENDLYLPHRTAQAFELAQFVRHTARGADVVIVTGDLNMEPCDLGF 223 Query: 181 KIISQLPSLLDPYNMKFEGTNP----------LIAKASGTSDNLNNSYSDPKQVKAYPEG 230 ++I L D + M E N IAK GT D +N Y+ + +K + Sbjct: 224 RLILSHAKLFDAWRMSHEVENEDSEGELLKFRGIAK-GGTCDRPDNCYT-KRALKNVDDS 281 Query: 231 KRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQE 290 KRID++LF + ++ L +++P + +YSDH V L ++ +++ Sbjct: 282 KRIDYMLFKSGRC-NVKLEECEITL-NQIPGEDLNYSDH--VGLRARFTIDDRFRHEKSV 337 Query: 291 SVDSAFQETITQAIKVCRDATTNXXXXXXXXXXXXXXIFMFLLGSVGFWPNFLIYDVLKL 350 + + + +AI + + +LGS+ F + + VL+ Sbjct: 338 NTWEPNRPLLIEAIGLVAGGERRARTDRIFFFILAVICLILILGSLFFEVFPMGFAVLRF 397 Query: 351 LITALCFYNLVMGSLWNQIEMNSLKAGLNALENFI 385 +T + + + G + +E +LKA A++ + Sbjct: 398 ALTVVGVFFVWQGLIGLTLERKALKAAKQAIQQIL 432 >UniRef50_O60906 Cluster: Sphingomyelin phosphodiesterase 2; n=17; Amniota|Rep: Sphingomyelin phosphodiesterase 2 - Homo sapiens (Human) Length = 423 Score = 199 bits (485), Expect = 1e-49 Identities = 104/270 (38%), Positives = 153/270 (56%), Gaps = 6/270 (2%) Query: 11 GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70 GIP +SK++ +R + +L + ++ L+EVWSE+D+ YL++ L P +++F SG+ Sbjct: 18 GIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYPAAHHFRSGI 77 Query: 71 LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130 +GSGLCVFSK IQ++ H + LNGY + IHHGDWF GK VGL + ++N Y THL Sbjct: 78 IGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHL 137 Query: 131 HAEYH-EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSL 189 HAEY+ + D+YLAHRV QA+ A+F+ TS ADV +L GDLN P DL ++ + L Sbjct: 138 HAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGL 197 Query: 190 LDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEARVV 249 D Y E T G + N Y +++K +P G RID++L+ + Sbjct: 198 HDAY---LE-TRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCK 253 Query: 250 NFGNPLPDRVPEQQFSYSDHNAVSLELHLK 279 +F P SDH A+ L ++ Sbjct: 254 SF-ETTTGFDPHSGTPLSDHEALMATLFVR 282 >UniRef50_Q4LEU0 Cluster: Mg2+-dependent neutral sphingomyelinase; n=7; Clupeocephala|Rep: Mg2+-dependent neutral sphingomyelinase - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 420 Score = 198 bits (482), Expect = 3e-49 Identities = 109/271 (40%), Positives = 155/271 (57%), Gaps = 10/271 (3%) Query: 11 GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70 GI +SK +RYE I L + +H+I LQEVWSE+D+L+LK L PY++YF SGV Sbjct: 18 GIRFLSKLCAQRYEMIGELLGREQHDIALLQEVWSERDFLFLKRKLSCSHPYTHYFKSGV 77 Query: 71 LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130 +GSGL VFSK IQD +Q+ LNGY + + HGDWFGGK GL ++ +VY THL Sbjct: 78 IGSGLAVFSKHRIQDALLYQYSLNGYPYMLSHGDWFGGKAAGLVIVEVFGLKAHVYVTHL 137 Query: 131 HAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSL 189 HAEY D YL HR++Q++ +FV+ TS AD+ IL GDLN P DL +++ L Sbjct: 138 HAEYSRAQDGYLPHRIVQSWELQQFVRHTSHGADLVILGGDLNMHPSDLGNRLLRSHTGL 197 Query: 190 LDPYNM--KFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEAR 247 Y KF+G G + NN ++ + + + +G RID+IL + + Sbjct: 198 RGCYTETDKFDGCE------DGHTLIANNHFTKKQDLIPFEKGIRIDYILMKGSQRVSVK 251 Query: 248 VVNFGNPLPDRVPEQQFSYSDHNAVSLELHL 278 + + V ++ F YSDH A+ +L+L Sbjct: 252 CESL-STTKGSVSDKPFPYSDHEALMADLNL 281 >UniRef50_UPI0000E490B9 Cluster: PREDICTED: similar to LD24865p; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LD24865p - Strongylocentrotus purpuratus Length = 212 Score = 168 bits (408), Expect = 3e-40 Identities = 81/192 (42%), Positives = 116/192 (60%), Gaps = 6/192 (3%) Query: 11 GIPV-VSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSG 69 G+P VSK++ ER + I+ L ++IV LQE+W +DY +K ++ VLP+S+YF G Sbjct: 12 GLPFGVSKHRSERMQHIAKELASGAYDIVSLQEIWVMEDYQLIKSTVEKVLPHSFYFRMG 71 Query: 70 VLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTH 129 +L GLC+FSKW I D F+H + LNGY HK+ DW+ K V LC++ +NVY TH Sbjct: 72 MLHGGLCIFSKWPIIDTFYHPYSLNGYAHKVTMADWYISKMVALCKLDVEGMTVNVYNTH 131 Query: 130 LHAEY-----HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIIS 184 HA Y E D +L HR+ Q Y +EFV+LTS AD+ ++ GD N+ P L+ K+ Sbjct: 132 AHALYAPSNIPEKDEFLTHRLTQLYELSEFVRLTSGAADLVLVTGDFNSEPFSLATKLAV 191 Query: 185 QLPSLLDPYNMK 196 LLD + + Sbjct: 192 SNARLLDAWETR 203 >UniRef50_A7S570 Cluster: Predicted protein; n=2; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 163 Score = 154 bits (374), Expect = 3e-36 Identities = 75/146 (51%), Positives = 100/146 (68%), Gaps = 6/146 (4%) Query: 11 GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70 GIP +SK KER+ I+ L +++IV LQEVWS+ DY L+ N+ LP+S YFYSGV Sbjct: 23 GIPFISKQVKERFGHIAKELASGKYDIVSLQEVWSKADYDVLRSNVSKTLPHSMYFYSGV 82 Query: 71 LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130 CVFS++ I + F +++ LNGY++KI HGDWFGGK G C I R I+ + THL Sbjct: 83 -----CVFSRYPIIESFTYRYTLNGYMYKIAHGDWFGGKSSGYCVIDHPLRPIHFFTTHL 137 Query: 131 HAEYH-EDDMYLAHRVLQAYSTAEFV 155 HAEY+ ++D YLAHRV QAY A+F+ Sbjct: 138 HAEYNRKNDEYLAHRVTQAYQLAQFI 163 >UniRef50_Q5D9I7 Cluster: SJCHGC06222 protein; n=1; Schistosoma japonicum|Rep: SJCHGC06222 protein - Schistosoma japonicum (Blood fluke) Length = 213 Score = 149 bits (362), Expect = 1e-34 Identities = 73/185 (39%), Positives = 107/185 (57%), Gaps = 4/185 (2%) Query: 13 PVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGVLG 72 P + K++R AI++ L + +++ LQE+W E DY L+ L + PYS YFY ++G Sbjct: 19 PSSTVRKEDRVNAIASKLANGDFDVILLQEIWLESDYRKLRLLLDDKYPYSNYFYCNLIG 78 Query: 73 SGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERL-INVYCTHLH 131 +G+C+FSKW+I+ VF H + NGY H IH D++ GKG+GL RI E IN Y THL Sbjct: 79 TGMCIFSKWIIECVFTHPFTTNGYPHLIHQADYYCGKGIGLARITSKEGFRINFYVTHLI 138 Query: 132 AEYHED---DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPS 188 A Y D D Y HR+ Q EFV++TS+ +D I+ GD N + +++ Sbjct: 139 ARYELDRMLDKYNGHRISQLVEVMEFVRMTSTGSDAIIITGDFNLESNTSAIELLCTSLK 198 Query: 189 LLDPY 193 L D + Sbjct: 199 LSDAW 203 >UniRef50_O74369 Cluster: Putative neutral sphingomyelinase; n=3; Schizosaccharomyces pombe|Rep: Putative neutral sphingomyelinase - Schizosaccharomyces pombe (Fission yeast) Length = 424 Score = 139 bits (337), Expect = 1e-31 Identities = 92/285 (32%), Positives = 149/285 (52%), Gaps = 19/285 (6%) Query: 11 GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70 G+ VSK + ER +A+ L K +++IV LQEVWS D+ ++ + L YS +F+S Sbjct: 18 GLRFVSKYRTERLKAVGEKLAKCDYDIVLLQEVWSIYDFQEIRNLVSCNLVYSRFFHSAA 77 Query: 71 LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF-GERLINVYCTH 129 +G+GL +FSK+ I + +++PLNG GDW+ GKGV ++ R+I+++ TH Sbjct: 78 MGAGLAMFSKFPIIESSMNKYPLNGRPQAFWRGDWYVGKGVATASLQHPSGRIISLFNTH 137 Query: 130 LHAEYHED-DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPS 188 LHA Y + D YL HR+ QA+ ++ ++ + I AGD N P + ++II+ Sbjct: 138 LHAPYGKGADTYLCHRLSQAWYISKLLRAAVQRGHIVIAAGDFNIQPLSVPHEIITSYGL 197 Query: 189 LLD------------PYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPE--GKRID 234 + D P N L+ A T D+ N++ + K + KR+D Sbjct: 198 VNDAWLSVYPDQVEHPPNRFSMNDKELVEIAGTTCDSRLNTWRENISSKDMDDFVAKRLD 257 Query: 235 HILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLK 279 ++ FH+ + EA+ N +RVP+ SYSDH A+ L +K Sbjct: 258 YV-FHSPSTCEAK--NAKVVFLERVPKLDCSYSDHFAIETVLSIK 299 >UniRef50_A4QVL4 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 649 Score = 134 bits (325), Expect = 3e-30 Identities = 72/201 (35%), Positives = 111/201 (55%), Gaps = 6/201 (2%) Query: 3 INLMLL-LRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLP 61 IN++ L G+ VSK + ER I L + IV LQEVWSE+DY L+ + VLP Sbjct: 6 INIVTLNCWGLRFVSKWRSERILEIGRRLSTTAPGIVALQEVWSEEDYEILRRETRAVLP 65 Query: 62 YSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG-- 119 Y +++GV GSGL + S+W +++ Q+PLNG GDW+ GKGV RI++G Sbjct: 66 YGKQYHAGVFGSGLVILSRWPLEESSMFQFPLNGRPTAFFRGDWYAGKGVAHARIRYGPQ 125 Query: 120 -ERLINVYCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPG 176 ++I V+ H HA Y + D Y AHR QA+ A+ ++ S + + GDLN P Sbjct: 126 KSQVIEVFNIHTHAAYETEAKDSYAAHRASQAWFFAKLLRSASERGHLVVGLGDLNAPPF 185 Query: 177 DLSYKIISQLPSLLDPYNMKF 197 L +++++ + D + + + Sbjct: 186 SLPHRLVTAQAPVRDAWRVLY 206 >UniRef50_Q6C8M5 Cluster: Yarrowia lipolytica chromosome D of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome D of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 454 Score = 134 bits (324), Expect = 4e-30 Identities = 93/297 (31%), Positives = 147/297 (49%), Gaps = 25/297 (8%) Query: 11 GIPVVSKNKKERYEAISTYLLKS--EHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYS 68 G+ +VSK + R EAIS L + ++IVCLQEVW E D+ +K+ + PY+ Y+YS Sbjct: 60 GLKLVSKLRPLRLEAISAQLAQDGDSYDIVCLQEVWVESDFDQIKKACVDHFPYTKYYYS 119 Query: 69 GVL-GSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF-GERLINVY 126 G++ G GL V S+W I+ + H++ LNG GDW+ GK V I I + Sbjct: 120 GIIAGPGLAVLSRWPIESAYVHRFGLNGRPSAFFRGDWYVGKSVASATIIHPSNHRIEIL 179 Query: 127 CTHLHAEYHEDDM-YLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQ 185 H+HA Y D Y HR QA+ A K + +++I+ GDLN+ P L++++ Sbjct: 180 NAHMHAPYGPGDANYTCHRTSQAWEMARIAKRSMDAGNLTIVTGDLNSRPSSLTHQLFEN 239 Query: 186 LPSLLDPYNMK---FEG------TNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHI 236 + L D + + F G I +A T ++ NS+ + + + R+D+I Sbjct: 240 MALLQDAWESRHGEFSGDLSEMTPEQQIEEAGVTCNSRLNSW---RASRPLSDACRLDYI 296 Query: 237 LFHTNHSW--EARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQES 291 F + + EARV D++ E S SDH VS L P ++ +++ S Sbjct: 297 FFDPSRATVREARVA-----FTDKI-EGGCSVSDHFGVSAVFELTPQDKSRHRKVSS 347 >UniRef50_A1CTA2 Cluster: Sphingomyelinase family protein, putative; n=9; Pezizomycotina|Rep: Sphingomyelinase family protein, putative - Aspergillus clavatus Length = 482 Score = 133 bits (322), Expect = 7e-30 Identities = 64/180 (35%), Positives = 102/180 (56%), Gaps = 7/180 (3%) Query: 11 GIPVVSKNKKERYEAISTYLLKSEH--NIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYS 68 G+ +SK + ER I L ++ IV LQE W+++DY +++ +++LPY +++ Sbjct: 27 GLKYISKFRHERMSEIGRQLAIADPPPQIVGLQECWTQQDYESIRQQTRDILPYGKFYFG 86 Query: 69 GVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG---ERLINV 125 G+ G+GL + SKW I++ +PLNG GDWF GKGV RI+FG + + V Sbjct: 87 GIFGAGLAILSKWPIEESSMFAYPLNGRPTAFFRGDWFVGKGVACARIRFGPAAQDVAEV 146 Query: 126 YCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKII 183 +CTHLHA Y + D YL HR QA+ A+ ++ + + I GD N P ++++I Sbjct: 147 FCTHLHAPYEREPHDSYLCHRTAQAWEIAKLMRGAAERGHLVIGLGDFNMIPSSFAHRLI 206 >UniRef50_Q2UM93 Cluster: Sphingomyelinase family protein; n=3; Trichocomaceae|Rep: Sphingomyelinase family protein - Aspergillus oryzae Length = 476 Score = 133 bits (321), Expect = 9e-30 Identities = 62/180 (34%), Positives = 105/180 (58%), Gaps = 7/180 (3%) Query: 11 GIPVVSKNKKERYEAISTYLLKSEH--NIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYS 68 G+ ++K + ER I L ++ IV LQE W+++DY ++E +++LPY +++ Sbjct: 25 GLKYLAKYRHERLSEIGRQLALADPAPEIVGLQECWTQQDYESIREQTRHLLPYGKFYFG 84 Query: 69 GVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG---ERLINV 125 GV+G+GL + SKW I++ + +PLNG GDW+ GKGV R++FG + V Sbjct: 85 GVMGAGLAILSKWPIEESSMYGYPLNGRPTAFFRGDWYVGKGVACARVRFGPGASDVAEV 144 Query: 126 YCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKII 183 +CTHLHA Y ++ D Y+ HR QA+ A+ ++ + ++I GD N P ++++I Sbjct: 145 FCTHLHAPYEKEPNDSYICHRTAQAWEIAKLMRGAAERGHLAIGLGDFNMVPSSFAHQLI 204 >UniRef50_P40015 Cluster: Inositol phosphosphingolipids phospholipase C; n=7; Saccharomycetales|Rep: Inositol phosphosphingolipids phospholipase C - Saccharomyces cerevisiae (Baker's yeast) Length = 477 Score = 132 bits (318), Expect = 2e-29 Identities = 80/260 (30%), Positives = 131/260 (50%), Gaps = 19/260 (7%) Query: 34 EHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGVL-GSGLCVFSKWVIQDVFFHQWP 92 +++++ LQE+W +D+ YL + PY F+SG+L G GL + SK I+ F +++P Sbjct: 92 DYDVIALQEIWCVEDWKYLASACASKYPYQRLFHSGILTGPGLAILSKVPIESTFLYRFP 151 Query: 93 LNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHLHAEYHE--DDMYLAHRVLQAYS 150 +NG + GDW+ GK + + + G R I + +H+HA Y + D YL HR QA+ Sbjct: 152 INGRPSAVFRGDWYVGKSIAITVLNTGTRPIAIMNSHMHAPYAKQGDAAYLCHRSCQAWD 211 Query: 151 TAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPYNM--------KFEGTNP 202 + +KL I+ GDLN+ PG L +K ++Q L+D + +P Sbjct: 212 FSRLIKLYRQAGYAVIVVGDLNSRPGSLPHKFLTQEAGLVDSWEQLHGKQDLAVIARLSP 271 Query: 203 L--IAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVP 260 L + K T D+L N++ +Q E R+D+ L + + V+ G +R+P Sbjct: 272 LQQLLKGCTTCDSLLNTWRAQRQP---DEACRLDYALIDPDF---LQTVDAGVRFTERIP 325 Query: 261 EQQFSYSDHNAVSLELHLKP 280 S SDH A S L++ P Sbjct: 326 HLDCSVSDHFAYSCTLNIVP 345 >UniRef50_Q4PAL6 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 525 Score = 125 bits (301), Expect = 2e-27 Identities = 85/261 (32%), Positives = 130/261 (49%), Gaps = 12/261 (4%) Query: 5 LMLLLRGIPVVSKNKKERYEAISTYLLKSE---HNIVCLQEVWSE-KDYLYLKENLKNVL 60 L L + G+ +SK + R +AI++ L S+ ++ VCLQE+W E +D+ +LK L + Sbjct: 42 LTLNVWGLKYISKLRIARIKAIASRLASSDMPLYDFVCLQEIWYESRDWRFLKHALSSRY 101 Query: 61 PYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGE 120 P+S +FYSG GSGL + S+W I + H + LNG +HHGDWF GK G I Sbjct: 102 PHSKFFYSGAFGSGLAILSRWNILETRTHPYSLNGQPIHVHHGDWFVGKACGSVTINHPR 161 Query: 121 -RLINVYCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGD 177 L++V+ TH A ED + +HR+ QAY A + ++S + GDLN+ P Sbjct: 162 LGLVDVWNTHFVAAGGEDGPEYKRSHRITQAYELAANCRNSASKGRHVVCVGDLNSTPPS 221 Query: 178 LSYKIISQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHIL 237 L+ ++ + L D F T P + + + + D S + A P+ +R L Sbjct: 222 LAIGLLRHIGGLYD----SFLDTRPQLPEHAVSLDPEETSTQVGDRATAAPDPQRAIEEL 277 Query: 238 FHTNHSWEARVVNFGNPLPDR 258 T S G PL +R Sbjct: 278 GVTCDS-PLNTWTAGKPLDER 297 >UniRef50_A3LY15 Cluster: Phospholipase C type enzyme; n=5; Saccharomycetales|Rep: Phospholipase C type enzyme - Pichia stipitis (Yeast) Length = 442 Score = 124 bits (300), Expect = 3e-27 Identities = 91/301 (30%), Positives = 145/301 (48%), Gaps = 31/301 (10%) Query: 11 GIPVVSKNKKERYEAISTYLL-----KSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYY 65 G+ +SK +++R AI+ L E++IV LQEVW E D+ YL K V PY Sbjct: 34 GLKYISKFRRQRLRAIANKLAYPATKDDEYDIVALQEVWCEDDWKYLDGTCKKVYPYRRV 93 Query: 66 FYSGVL-GSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF---GER 121 F SG++ G GL + SK I + F +++P+NG GDW GK + + +K G Sbjct: 94 FKSGIVTGPGLVLLSKIPIDESFLYRFPINGRASAFFRGDWLVGKSIAITLLKPHQPGAM 153 Query: 122 LINVYCTHLHAEYHE--DDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLS 179 I + +H+HA Y + ++ Y HR QA+ A+ VK+ I GDLN+ PG L Sbjct: 154 PIALLNSHMHAPYAQSGENSYSTHRACQAWDFAKLVKMLRRSGYAVIQVGDLNSKPGSLP 213 Query: 180 YKIISQLPSLLDPYNMKFEGTNPL-------------IAKASGTSDNLNNSYSDPKQVKA 226 YK+ + L D +++ ++ + L I KA T +N N++ ++ Sbjct: 214 YKLFTVEGGLSDSWDLCYDKESQLTIEDLAAMQPLEQIHKAGTTVNNQLNTWRAHSDIR- 272 Query: 227 YPEGKRIDHILFHT-NHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKL 285 + R+D+ L N + V F LP P S+SDH + EL ++ ++L Sbjct: 273 --DACRLDYALIDAHNIKPISAAVKFTEKLP---PPYNCSFSDHFGYTAELQIRSDGEEL 327 Query: 286 N 286 + Sbjct: 328 D 328 >UniRef50_Q2HD33 Cluster: Putative uncharacterized protein; n=2; Sordariales|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 574 Score = 121 bits (291), Expect = 4e-26 Identities = 61/198 (30%), Positives = 111/198 (56%), Gaps = 9/198 (4%) Query: 3 INLMLL-LRGIPVVSKNKKERYEAISTYLLKS--EHNIVCLQEVWSEKDYLYLKENLKNV 59 INL+ L G+ +SK ++ER I L + + +IV LQE ++++DY ++ ++ + Sbjct: 8 INLVTLNCWGLKYISKLRRERLTEIGRQLATASPQPHIVALQECFTQEDYQSIRHEVRFI 67 Query: 60 LPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG 119 LPY +++S G GL + S+W I++ +++PLNG GDW+ GKG+ +I++G Sbjct: 68 LPYGKFYHSAAFGGGLAILSRWPIEESTMYRYPLNGRPTAFWRGDWYVGKGIACAKIRYG 127 Query: 120 ---ERLINVYCTHLHAEYH---EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNT 173 ++++ V+ TH HA Y +D YL HR Q++ A+ ++ + + + GD N Sbjct: 128 PAAKQVVEVFNTHTHAPYEGGKPNDSYLCHRTAQSWEMAKLLRGAAERGHLVLAMGDFNM 187 Query: 174 APGDLSYKIISQLPSLLD 191 P Y++I+ L + D Sbjct: 188 IPMSREYQLITGLAPVSD 205 >UniRef50_Q1HG89 Cluster: Inositol phosphorylsphingolipid-phospholipase C; n=3; Filobasidiella neoformans|Rep: Inositol phosphorylsphingolipid-phospholipase C - Cryptococcus neoformans var. grubii (Filobasidiella neoformans var.grubii) Length = 529 Score = 115 bits (276), Expect = 3e-24 Identities = 75/245 (30%), Positives = 126/245 (51%), Gaps = 19/245 (7%) Query: 11 GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70 G+ +V+KN+ R AI+ YL S ++IVCLQE+W KDY ++E ++ LP+S +F++G Sbjct: 23 GLAIVAKNRHTRIHAIAEYLASSNYDIVCLQELWIYKDYEVVREEVQRNLPFSRFFHTGA 82 Query: 71 LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGK---GVGLCRIKFGERLINVYC 127 LGSGL +F+++ + + L+G + GD+F K V + GE + ++ Sbjct: 83 LGSGLAIFTRFPLIAAHALPYSLSGSPAQAFAGDFFVKKAAANVVILHPVLGE--VEIWN 140 Query: 128 THLHAE-YHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQL 186 TH+HA H D AHR+ Q++ A V+ ++ + GD N+ P + ++ Sbjct: 141 THMHAAGEHPPDTRQAHRIAQSWQLANAVRGGAAKGRYVFVMGDFNSQPWSIPIAMMRDH 200 Query: 187 PSLLDPYNMKFEGTNPLIA---------KASG-TSDNLNNSYSDPKQVKAY---PEGKRI 233 L+D ++ N I+ K G T D+ N+YS K + + GKR+ Sbjct: 201 AQLMDSFDQVHPSANSEISPPPSPAEALKVYGMTCDSPLNTYSAGKPIPEHVLEKGGKRL 260 Query: 234 DHILF 238 D+I F Sbjct: 261 DYIFF 265 >UniRef50_A5DP62 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 468 Score = 110 bits (264), Expect = 7e-23 Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 12/197 (6%) Query: 11 GIPVVSKNKKERYEAISTYLLKS------EHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 64 G+ VSK ++ R AI+ L + +++IV LQEVW +D+ YL +N+ PY Sbjct: 35 GLKYVSKYRRFRLCAIADRLANAVPGSQDDYDIVALQEVWCSEDWEYLSSRCENLYPYRR 94 Query: 65 YFYSGVL-GSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIK---FGE 120 F SG++ G GLC+ SK I++ F +++P+NG GDW GK + + ++ G Sbjct: 95 NFNSGIITGPGLCILSKVPIKETFLYRFPINGRPSAFFRGDWMVGKSISVTLLQPHTKGA 154 Query: 121 RLINVYCTHLHAEY--HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDL 178 I + +H+HA Y D Y HR QA+ + V++ + GDLN+ PG L Sbjct: 155 LPIALLNSHMHAPYALTGDAAYSCHRACQAWDFTKLVRMLKRAGYAVVQVGDLNSRPGSL 214 Query: 179 SYKIISQLPSLLDPYNM 195 YK+ + L D +++ Sbjct: 215 PYKLFTVEGGLEDSWDV 231 >UniRef50_Q4DIM2 Cluster: Putative uncharacterized protein; n=1; Trypanosoma cruzi|Rep: Putative uncharacterized protein - Trypanosoma cruzi Length = 597 Score = 92.7 bits (220), Expect = 2e-17 Identities = 89/285 (31%), Positives = 130/285 (45%), Gaps = 43/285 (15%) Query: 18 NKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENLKNVLPYSYYFY---SGVLGS 73 N K R ++ + K H +I+ LQE +S++D+ + NL + + YF S GS Sbjct: 17 NSKYRAARMARFAAKVAHYDIILLQEQFSKEDFELIISNLPSEVREKRYFKRFPSAFYGS 76 Query: 74 GLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG---ERLIN------ 124 G+ V S++ I+ F +PL GY ++ HGD++ KG L RI R ++ Sbjct: 77 GIAVISRFPIKSALFFTFPLQGYPERVLHGDYYANKGASLLRIHVPCTTRRGVSPDPPYE 136 Query: 125 ---VYCTHLHAEYHE--------DDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNT 173 +Y THL A Y + D++YL R+ QA S AEF+ TS P D I+ GD N Sbjct: 137 DVLLYNTHLVAAYQKTARLLNWRDELYLPVRLSQAISLAEFISSTSHPTDRVIIGGDFNA 196 Query: 174 APGDL------------SYKIISQLPSLLDPYNMKFEGTNPLIAKASGT-SD-NLNNSYS 219 L YK++S LP + Y + I A+ T SD N+ NS Sbjct: 197 TQRSLELQAMLILLRKRGYKLVSVLPPSI-MYRPEMSEREKRINTATLTYSDANMFNSPK 255 Query: 220 DPKQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQF 264 D V+ +IDHI F +N R+ F N PD + F Sbjct: 256 DGWFVEGGDVPCQIDHIFFTSN---TLRLSAF-NDCPDAAADYPF 296 >UniRef50_Q4QIE9 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 653 Score = 89.8 bits (213), Expect = 1e-16 Identities = 58/188 (30%), Positives = 91/188 (48%), Gaps = 22/188 (11%) Query: 18 NKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENLKNVLPYSYYFY---SGVLGS 73 N + R + + K EH +++ LQE +S +D+ + +N V+ +Y F S GS Sbjct: 26 NSRMREARMKVFATKIEHYDVILLQEQFSVEDFDLIFQNASPVVQRTYTFRRFCSSFYGS 85 Query: 74 GLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERL----------I 123 G V S++ I FFH +PL GY + HGD+F KG + R+ + + Sbjct: 86 GCAVISRYPISQAFFHTFPLQGYPEMVLHGDFFANKGAAMVRVMVPVTMADGGAAKAQEV 145 Query: 124 NVYCTHLHAEYHE--------DDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAP 175 +Y THL A Y + + YL R+ QA S A+F+ TS P D I+ GD N + Sbjct: 146 TLYTTHLVAVYEKVSQLSSWRRERYLPFRISQAISFADFIVSTSRPTDPIIIGGDFNCSQ 205 Query: 176 GDLSYKII 183 L +++ Sbjct: 206 RSLEVQMM 213 >UniRef50_Q57U95 Cluster: Sphingomyelin phosphodiesterase, putative; n=1; Trypanosoma brucei|Rep: Sphingomyelin phosphodiesterase, putative - Trypanosoma brucei Length = 580 Score = 82.2 bits (194), Expect = 2e-14 Identities = 59/181 (32%), Positives = 93/181 (51%), Gaps = 25/181 (13%) Query: 18 NKKERYEAISTYLLKSE-HNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFY---SGVLGS 73 N K R E ++ + K E ++I+ LQE +SE D+ + +N+ + + YF + GS Sbjct: 17 NSKHRPERMAHFASKVEDYDIILLQEQFSESDFDIIIQNMPEEVRRTRYFKRYPTAFYGS 76 Query: 74 GLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVG-LC---------RIKFGE--- 120 G+ V S++ ++ F +PL G+ ++ HGD++ KG LC + G Sbjct: 77 GIAVISRFPVKSGVFFTFPLQGFPEQVLHGDYYANKGAAMLCVSVPCNNDVEVSGGSVMH 136 Query: 121 RLINVYCTHLHAEYH--------EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLN 172 R + VY THL A Y D++YLA R+ QA S A F+ TS+P D I+ GD N Sbjct: 137 RDVLVYSTHLVAVYQVPSQLRDWRDEVYLAVRLSQAISFANFIIATSNPTDHIIIGGDFN 196 Query: 173 T 173 + Sbjct: 197 S 197 >UniRef50_UPI000023DADB Cluster: hypothetical protein FG01057.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG01057.1 - Gibberella zeae PH-1 Length = 476 Score = 54.8 bits (126), Expect = 4e-06 Identities = 26/87 (29%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Query: 3 INLMLL-LRGIPVVSKNKKERYEAISTYLLKS--EHNIVCLQEVWSEKDYLYLKENLKNV 59 INL+ L G+ +S + R + I + + IV LQE ++++DY ++ + + + Sbjct: 31 INLLTLNCWGLRYISTQRNARLDEIGRRIAHAVPTPQIVALQECFTQEDYEAIRHHTRQI 90 Query: 60 LPYSYYFYSGVLGSGLCVFSKWVIQDV 86 LPY +++SG G GL + S W I+++ Sbjct: 91 LPYGKFYHSGAFGGGLAILSHWPIEEI 117 >UniRef50_Q5TEC8 Cluster: Sphingomyelin phosphodiesterase 2, neutral membrane; n=2; Homo/Pan/Gorilla group|Rep: Sphingomyelin phosphodiesterase 2, neutral membrane - Homo sapiens (Human) Length = 203 Score = 46.8 bits (106), Expect = 0.001 Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 5/122 (4%) Query: 158 TSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNS 217 TS ADV +L GDLN P DL ++ + L D Y E T G + N Sbjct: 62 TSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAY---LE-TRDFKGSEEGNTMVPKNC 117 Query: 218 YSDPKQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELH 277 Y +++K +P G RID++L+ + +F P + SDH A+ L Sbjct: 118 YVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSF-ETTTGFDPHRGTPLSDHEALMATLF 176 Query: 278 LK 279 ++ Sbjct: 177 VR 178 >UniRef50_A0DMK4 Cluster: Chromosome undetermined scaffold_56, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_56, whole genome shotgun sequence - Paramecium tetraurelia Length = 352 Score = 42.3 bits (95), Expect = 0.022 Identities = 54/182 (29%), Positives = 83/182 (45%), Gaps = 30/182 (16%) Query: 13 PVVSKN----KKERYEAISTYLLKSEHNIVCLQEVW----SEKDYLYLKE-----NLKNV 59 PVV+ N K ER E I L+ + IVCLQEV+ S K L K + V Sbjct: 33 PVVNNNGDDYKNERCELIIKELMNFD--IVCLQEVFGFLNSRKSILKHKAFKLGFTYQAV 90 Query: 60 LPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG 119 P +F S ++ GL S++ I F ++P G + D KGV +I Sbjct: 91 SPSPSFFSSQMVDGGLVTLSRYPILSHEFKEFPY-GIL-----SDNLSNKGVLYTKILVN 144 Query: 120 ERLINVYCTHLHAEY--HEDDM--YLAHRVLQAYSTAEFVKLT-----SSPADVSILAGD 170 ++++++ THL A Y E ++ ++ R+ Q Y +FV T + D+ +L GD Sbjct: 145 GQMLHLFNTHLQASYVGKESNVRATVSTRIDQLYCFKKFVHSTLEQQQAQENDLILLVGD 204 Query: 171 LN 172 N Sbjct: 205 YN 206 >UniRef50_UPI0000F21D16 Cluster: PREDICTED: similar to Mg2+-dependent neutral sphingomyelinase, partial; n=1; Danio rerio|Rep: PREDICTED: similar to Mg2+-dependent neutral sphingomyelinase, partial - Danio rerio Length = 145 Score = 41.9 bits (94), Expect = 0.029 Identities = 18/34 (52%), Positives = 24/34 (70%) Query: 69 GVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHH 102 GV+GSGL VFSK IQD +Q+ LNGY + + + Sbjct: 1 GVIGSGLAVFSKHRIQDALLYQYSLNGYPYMVSY 34 >UniRef50_Q9NY59 Cluster: Sphingomyelin phosphodiesterase 3; n=22; Euteleostomi|Rep: Sphingomyelin phosphodiesterase 3 - Homo sapiens (Human) Length = 655 Score = 41.1 bits (92), Expect = 0.051 Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 22/141 (15%) Query: 36 NIVCLQEVWSEKDYLYLKENLKNVLPYSYY---FYS-------GVLGSGLCVFSKWVIQD 85 + +CLQEV+ ++ LKE L Y Y Y L SGL S++ I D Sbjct: 358 DFLCLQEVFDKRAATKLKEQLHGYFEYILYDVGVYGCQGCCSFKCLNSGLLFASRYPIMD 417 Query: 86 VFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG-----ERLIN-VYCTHLHAEYHEDDM 139 V +H +P +K + D KG +++ G +R++ + CTHLHA + + Sbjct: 418 VAYHCYP-----NKC-NDDALASKGALFLKVQVGSTPQDQRIVGYIACTHLHAPQEDSAI 471 Query: 140 YLAHRVLQAYSTAEFVKLTSS 160 L A+F K TSS Sbjct: 472 RCGQLDLLQDWLADFRKSTSS 492 >UniRef50_Q2SCA2 Cluster: Endonuclease/exonuclease/phophatase family protein; n=2; Oceanospirillales|Rep: Endonuclease/exonuclease/phophatase family protein - Hahella chejuensis (strain KCTC 2396) Length = 445 Score = 40.7 bits (91), Expect = 0.067 Identities = 49/175 (28%), Positives = 75/175 (42%), Gaps = 20/175 (11%) Query: 4 NLMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPY- 62 N LL G+ +SKN R ++ + ++ V QEV+ + +L+ PY Sbjct: 182 NAWALLPGL--MSKNTSNRLATMAEAV--KGYDAVVFQEVFDPILTARFRSDLQAEYPYL 237 Query: 63 -SYYFYSG-VLGSGLCVFSKWVI--QDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF 118 F G +L G + S+W I QD ++ N F KG +I Sbjct: 238 TEIPFKLGRLLTGGSFIASRWPILAQDAMVYEGCRND--------GCFASKGANYAKIDK 289 Query: 119 GERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVS-ILAGDLN 172 G ++ +++ H HA E+D+ L LQ Y FV + AD I+AGDLN Sbjct: 290 GGQIYHLFGAHTHAYTGEEDVALRRWHLQQYKA--FVDSKGAAADEPVIIAGDLN 342 >UniRef50_P17627 Cluster: Sphingomyelinase C precursor; n=5; Leptospira|Rep: Sphingomyelinase C precursor - Leptospira interrogans Length = 556 Score = 40.3 bits (90), Expect = 0.089 Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 10/128 (7%) Query: 74 GLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHLHAE 133 G+ + SKW I++ H + G D F KG RI R ++ TH+ A+ Sbjct: 179 GVVIVSKWPIEEKIQHVFKEKGC-----GADVFSNKGFAYVRIDKNGRKFHIIGTHVQAQ 233 Query: 134 YHE-DDMYLAHRVLQAYSTAEFVKLTSSPA-DVSILAGDLNTAPGDLSYKIISQLPSLLD 191 ++ + RV Q +F+ P ++ ++AGDLN G Y Q+ +L+ Sbjct: 234 DSGCANLGVVSRVNQFNEIRDFIDSKKIPKNEMVLIAGDLNVIKGSREY---HQMLCILN 290 Query: 192 PYNMKFEG 199 N K+ G Sbjct: 291 VNNPKYVG 298 >UniRef50_A3Y6R9 Cluster: Putative uncharacterized protein; n=1; Marinomonas sp. MED121|Rep: Putative uncharacterized protein - Marinomonas sp. MED121 Length = 349 Score = 38.3 bits (85), Expect = 0.36 Identities = 53/201 (26%), Positives = 85/201 (42%), Gaps = 23/201 (11%) Query: 5 LMLLLRGIP-VVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKEN---LKNVL 60 L+ + G P + N K + + L +N+V +QE++SE + +K+ + Sbjct: 69 LVYNIDGFPECIGGNSKSDLKELLKRLESENYNLVLMQEMFSESKHDLVKDEDRLSQQAY 128 Query: 61 PYSYYFYSGVL---GSGLCVFSKWVIQ----DVFFHQWPLNGYI-HKIHHGDWFGG---- 108 PY + G + G GL S + Q D + N + + HG+ F Sbjct: 129 PYRSKHWRGGMTSYGDGLMRLSDFPFQMNSRDNDDYSLTSNEFEEYSACHGNLFDNSPDC 188 Query: 109 ---KGVGLCRIKFGERL-INVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADV 164 KG + + E ++VY TH++A EDD Y A R Q A+F+ SS A V Sbjct: 189 WTEKGFSVAVHEITEDFSVHVYNTHMNAGRDEDD-YNARR-KQFLQLADFINSYSSNATV 246 Query: 165 SILAGDLNTAPGDLSYKIISQ 185 I+ GD N D + + Q Sbjct: 247 -IIGGDFNNKWSDYPHAVEQQ 266 >UniRef50_Q93HR5 Cluster: Sphingomyelinase; n=2; cellular organisms|Rep: Sphingomyelinase - Pseudomonas sp. TK4 Length = 516 Score = 36.7 bits (81), Expect = 1.1 Identities = 52/232 (22%), Positives = 91/232 (39%), Gaps = 22/232 (9%) Query: 90 QWPLNGYIHKIHH----GDWFGGKGVGLCRIKFGERLINVYCTHLH-AEYHEDDMYLAHR 144 +WP+ + ++H D KG ++ GER +V TH A+ D A R Sbjct: 128 RWPIARRVQYLYHDACGADRLANKGFVYVKVLRGERPFHVIATHTQAADSACPDGGRAVR 187 Query: 145 VLQAYSTAEFVKLTSSPA-DVSILAGDLNTAPGDLSY-KIISQLPSLLDPYNMKFEGTNP 202 Q F+ + PA +V + GDLN G Y +++QL L +P + + G + Sbjct: 188 ESQFREMRAFIDRENIPANEVLFIGGDLNVIRGSDEYPHMLAQL-DLREPDS--YAGASA 244 Query: 203 LIAKASGTSDNLNNSYSD--PKQVKAYPEGKRIDHILFHTNHS----WEARVVNFGNP-- 254 Y D P + + P + +D+IL H W + ++ +P Sbjct: 245 TFDTRRNGVTGYQYPYKDNGPGKAPSNPP-EYLDYILVSNRHGQVSYWHNQALDIPSPRW 303 Query: 255 -LPDRVPEQQF-SYSDHNAVSLELHLKPCEQKLNQRQESVDSAFQETITQAI 304 D V + YSDH V+ + P Q + D+ + + +++ Sbjct: 304 SASDGVNTWYYQDYSDHYPVAAFTYADPLRTP-QQAYKPTDNRYARVVLRSL 354 >UniRef50_A2QPH4 Cluster: Transposase Tan1-Aspergillus niger; n=3; Aspergillus|Rep: Transposase Tan1-Aspergillus niger - Aspergillus niger Length = 555 Score = 36.3 bits (80), Expect = 1.4 Identities = 21/60 (35%), Positives = 26/60 (43%) Query: 254 PLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESVDSAFQETITQAIKVCRDATTN 313 P PD + HN L H K E+ L +RQ S S T+ Q +K C A TN Sbjct: 402 PTPDSQSSGSVLQTPHNIKHLLKHQKSVERLLRKRQASPTSPTNSTLRQLLKGCELAITN 461 >UniRef50_Q5KM82 Cluster: Trehalose-phosphatase, putative; n=2; Filobasidiella neoformans|Rep: Trehalose-phosphatase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 989 Score = 35.9 bits (79), Expect = 1.9 Identities = 34/140 (24%), Positives = 60/140 (42%), Gaps = 12/140 (8%) Query: 120 ERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLS 179 ER+ +H++ Y D H QA E+ L S AD++++ L S Sbjct: 531 ERMTAELVSHINGTYGSLDFTPVHHYHQALEKDEYFGLLSC-ADLALITS-LRDGMNTTS 588 Query: 180 YK-IISQLPSLLDPYNM-KFEGTNPLIAKAS--------GTSDNLNNSYSDPKQVKAYPE 229 + I+ Q + P + +F GT P A A G + +N + ++ KA Sbjct: 589 MEFILCQDKTSKSPLVLSEFMGTAPSFASALQINPHDLLGVAQAINKGLTMREEEKAERH 648 Query: 230 GKRIDHILFHTNHSWEARVV 249 ++ +L HT+H+W A ++ Sbjct: 649 ANLLEGVLAHTSHTWAATIL 668 >UniRef50_A1A5I2 Cluster: Zgc:154063; n=2; Danio rerio|Rep: Zgc:154063 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 969 Score = 35.5 bits (78), Expect = 2.5 Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 23/136 (16%) Query: 96 YIHKIHHGDWFGGKGVGLCRIKFGERLIN------VYCTHLHAEYHEDDMYLAHRVLQAY 149 YI KIH+ F K + R + L+N + C H H+ +HE + +AH L A+ Sbjct: 434 YIMKIHN---FTSKCLYCNRYLPSDSLLNHMLVHGLSCPHCHSTFHEVEKIVAHNRL-AH 489 Query: 150 STAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPYNMKFEGTNPLIAKASG 209 + + T SP L DL G+L + L+ YNMK P A A+ Sbjct: 490 PNEQGDQPTGSP-----LTFDLTLQQGNL-----KNVQLLVTTYNMK---ETPEAAAAAA 536 Query: 210 TSDNLNNSYSDPKQVK 225 ++ L+ + + PK VK Sbjct: 537 AANQLSQNSAMPKPVK 552 >UniRef50_A0DEC1 Cluster: Chromosome undetermined scaffold_48, whole genome shotgun sequence; n=4; Eukaryota|Rep: Chromosome undetermined scaffold_48, whole genome shotgun sequence - Paramecium tetraurelia Length = 1056 Score = 35.5 bits (78), Expect = 2.5 Identities = 57/251 (22%), Positives = 95/251 (37%), Gaps = 18/251 (7%) Query: 48 DYLYLKENLKNVLPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFG 107 D L+ + NL + PY+ S ++G + VF K ++ + K G G Sbjct: 575 DQLF-QSNLSKIEPYTKIGESDLVGLYMAVFVK---TSQISRVTQIDTDVVKTGLGGTLG 630 Query: 108 GKGVGLCRIKFGERLINVYCTHLHAEYHEDDMYLA--HRVLQAYSTAEFVKLTSSPADVS 165 KG + KF + + C HL + + L+ + Q K T + D S Sbjct: 631 NKGGVSVKFKFDDSQLGFTCCHLTSGNKQCQQRLSDVDEIHQRAFQNSKSKTTLNDLDYS 690 Query: 166 ILAGDLNTAPGDLSY-KIISQLPSLLDPYNMKFEGTNPLIAKA-SGTSDNLNNSYSDPKQ 223 GD+N DL Y ++I Q+ + N A D L + + + Sbjct: 691 FFFGDMNFRI-DLPYQEVIEQIRHYQQLISQDQNNPNAKAKLAYLLNQDQLGKNKNRNQY 749 Query: 224 VKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQ 283 ++ Y EG I F + ++ + R P S+ D VS + L C+Q Sbjct: 750 LQNYQEGS----IFFLPTYKYDKNCQVYDTSKKQRTP----SWCDRILVSCKEEL-ICQQ 800 Query: 284 KLNQRQESVDS 294 + +R E +DS Sbjct: 801 RFYKRNECLDS 811 >UniRef50_Q8CVD9 Cluster: Sphingomyelinase C; n=5; Leptospira interrogans|Rep: Sphingomyelinase C - Leptospira interrogans Length = 558 Score = 35.1 bits (77), Expect = 3.3 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 12/132 (9%) Query: 66 FYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHH--GDWFGGKGVGLCRIKFGERLI 123 F + G+ + SKW IQ+ YI K H D F KG +IK G ++I Sbjct: 164 FRQQINNGGVVILSKWPIQEKI-------QYIFKNHGCGNDTFYNKGFAYVKIKKGSQII 216 Query: 124 NVYCTHLHAEYHE-DDMYLAHRVLQAYSTAEFV-KLTSSPADVSILAGDLNTAPGDLS-Y 180 ++ T +E D+ + R+ Q +F+ S ++ ++AG LN + S Y Sbjct: 217 HIVGTDTQSEDSTCSDLGVNARINQLTEIKKFIDSKRISNKEIVLIAGALNVDKSNQSEY 276 Query: 181 KIISQLPSLLDP 192 K + + + +P Sbjct: 277 KNMLNILEVNEP 288 >UniRef50_Q5AVC8 Cluster: Ferrochelatase; n=9; Fungi/Metazoa group|Rep: Ferrochelatase - Emericella nidulans (Aspergillus nidulans) Length = 419 Score = 35.1 bits (77), Expect = 3.3 Identities = 17/37 (45%), Positives = 21/37 (56%) Query: 223 QVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRV 259 Q+K YPE KR +L + HS VVN G+P P V Sbjct: 239 QLKTYPEEKRNSVVLLFSAHSLPMSVVNRGDPYPAEV 275 >UniRef50_A7F024 Cluster: Predicted protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Predicted protein - Sclerotinia sclerotiorum 1980 Length = 880 Score = 35.1 bits (77), Expect = 3.3 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 2/68 (2%) Query: 200 TNPLIAKA-SGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDR 258 T+P++A+ + T+ +L +YS+ +Q P ++ DH+ H +E + GN PD Sbjct: 392 TSPILARELTATNRSLGGNYSESQQGSQSPGAEQSDHVGQHQLRRYETASEHHGN-RPDV 450 Query: 259 VPEQQFSY 266 V F Y Sbjct: 451 VSHPTFGY 458 >UniRef50_P59116 Cluster: Sphingomyelinase C 2 precursor; n=6; Leptospira interrogans|Rep: Sphingomyelinase C 2 precursor - Leptospira interrogans Length = 623 Score = 35.1 bits (77), Expect = 3.3 Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 9/123 (7%) Query: 67 YSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVY 126 YS V G G+ + SKW I++ + + +G DWF KG +I + +V Sbjct: 242 YSLVNG-GVVILSKWPIEEKIQYIFNDSGC-----GADWFANKGFVYVKINKEGKKFHVI 295 Query: 127 CTHLHAEYHE-DDMYLAHRVLQAYSTAEFVKLTSSPADVSIL-AGDLNT-APGDLSYKII 183 TH ++ ++ + +R Q F+ + P D ++L GDLN + Y +I Sbjct: 296 GTHAQSQDQNCSNLGIPNRANQFDDIRNFIYSKNIPKDETVLIVGDLNVIKESNEYYDMI 355 Query: 184 SQL 186 S+L Sbjct: 356 SRL 358 >UniRef50_O51552 Cluster: Rep helicase, single-stranded DNA-dependent ATPase; n=3; Borrelia burgdorferi group|Rep: Rep helicase, single-stranded DNA-dependent ATPase - Borrelia burgdorferi (Lyme disease spirochete) Length = 659 Score = 34.7 bits (76), Expect = 4.4 Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 336 VGFWPNFLIYDVLKLLITALCFYNLVMGSLWNQIEMNSLKAGLNALENFIQTRNDTKPED 395 +G+ NF IYD I+ L L G ++ +NSL ++ L+N I T ND K ED Sbjct: 105 LGYRKNFSIYDDNDR-ISLLKEILLDEGLFNKKVSLNSLSNVISLLKNGILTLNDLKEED 163 Query: 396 IN 397 IN Sbjct: 164 IN 165 >UniRef50_Q9N467 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 604 Score = 34.7 bits (76), Expect = 4.4 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 5/84 (5%) Query: 121 RLINVYCTHLHAEYHED---DMYLAHRVLQAYST-AEFVKLTSSPAD-VSILAGDLNTAP 175 R+IN Y T LHAE E +M + RV + + +E+ K + D +++++ DL A Sbjct: 94 RVINAYGTVLHAEVDEKVKLEMAMERRVYEELAPFSEYEKNVNKLKDKLNLVSTDLEIAQ 153 Query: 176 GDLSYKIISQLPSLLDPYNMKFEG 199 DL + LD MK+EG Sbjct: 154 KDLEKENSMTHQESLDAIQMKYEG 177 >UniRef50_Q4UHF9 Cluster: Putative uncharacterized protein; n=2; Theileria|Rep: Putative uncharacterized protein - Theileria annulata Length = 1233 Score = 34.7 bits (76), Expect = 4.4 Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 155 VKLTSSPADVSILAGDLNTAPG--DLSYKIISQLPSLLDPYNMKFEGTNPLIAKASGTSD 212 ++ T+ P+ V ++ DLN P DL ++ +PS +D N + + SGT Sbjct: 344 IQNTTIPSTVDLVTSDLNNIPSTVDLVNNDLNNIPSAVDLVNNDLNIPSAVNLVTSGTMV 403 Query: 213 NLNNSYSDPKQVKA 226 N N +D K+V++ Sbjct: 404 NGMNGMNDVKEVES 417 >UniRef50_A7AR39 Cluster: Endonuclease/exonuclease/phosphatase family protein; n=1; Babesia bovis|Rep: Endonuclease/exonuclease/phosphatase family protein - Babesia bovis Length = 319 Score = 34.7 bits (76), Expect = 4.4 Identities = 51/212 (24%), Positives = 87/212 (41%), Gaps = 28/212 (13%) Query: 26 ISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVL--------PYSYYFYSGVLGSGLCV 77 IS+ K + +I+ LQEV+S Y +K+ L+ + P S L + L Sbjct: 38 ISSLFQKYDVDIMVLQEVFSYSLYNKIKDALRGIAEDTGIISRPVSNSVLMSCLDTLLST 97 Query: 78 FSKWVIQDVFFHQWPLNGYIHKI-----HHGDWFGGKGVGLCRIKFGERLINVYCTHLHA 132 FS V F + P+ Y ++ + + + GKG RI L++V THL + Sbjct: 98 FSFITSGIVIFSRHPIV-YKERLLFSNGFNAERYAGKGAVAARISVNGNLLDVIGTHLQS 156 Query: 133 EYHEDDMYLAHRVLQAYSTAEFVKLT------------SSPADVSILAGDLNTAPGDLSY 180 + ED + ++ Q AE++ + S P +LAGDLN + + Sbjct: 157 DEGEDAQEIRNK--QLIELAEWIGINPLEDERAIAERDSLPYVPMVLAGDLNCSLDSETE 214 Query: 181 KIISQLPSLLDPYNMKFEGTNPLIAKASGTSD 212 + + +L D F P ++ T+D Sbjct: 215 RFSDVVAALNDKLEDTFGYNQPEPTYSTLTND 246 >UniRef50_P22657 Cluster: RNA replication protein (152 kDa protein) (ORF 1 protein) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); Helicase (EC 3.6.1.-)]; n=20; Carlavirus|Rep: RNA replication protein (152 kDa protein) (ORF 1 protein) [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); Helicase (EC 3.6.1.-)] - Potato virus S (strain Peruvian) Length = 353 Score = 34.7 bits (76), Expect = 4.4 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 6/59 (10%) Query: 32 KSEHNIVCLQE--VWSEKDYL-YLKENLKNVLPYSYYFYSGVLGSGLCVFSKWVIQDVF 87 K+ IVC Q + Y+ Y+++ L VLP ++Y +S G GL +KWVI+ F Sbjct: 80 KAAQTIVCFQHSVLCRFAPYMRYIEKKLNEVLPATFYIHS---GKGLEELNKWVIESKF 135 >UniRef50_UPI00006CF82F Cluster: Endonuclease/Exonuclease/phosphatase family protein; n=1; Tetrahymena thermophila SB210|Rep: Endonuclease/Exonuclease/phosphatase family protein - Tetrahymena thermophila SB210 Length = 480 Score = 34.3 bits (75), Expect = 5.8 Identities = 48/202 (23%), Positives = 90/202 (44%), Gaps = 29/202 (14%) Query: 2 IINLMLLLRGIPVVSKNKKERYEAISTYLLK---SEHNIVCLQEVW---SEKDYLYLKEN 55 ++ + LR P+ KN K+ Y+ T L S+ +IVCLQE++ +++ + + Sbjct: 79 VLTYNIFLRPPPI--KNNKDDYKNERTKLFLNSISDFDIVCLQELFGFLNQRKHKIIFNA 136 Query: 56 LKN------VLPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGK 109 +K P +F S ++ GL S++ I + + + G + D K Sbjct: 137 MKQGFFYHATSPSPSFFSSYLVDGGLVTISRFPIIEKSYRPFKY-GVL-----SDNLSQK 190 Query: 110 GVGLCRIKFGERLINVYCTHLHAEY--HEDDM--YLAHRVLQAYSTAEFV-----KLTSS 160 GV +I+ + I+++ THL A Y E+++ + RV Q +F+ K Sbjct: 191 GVLYTKIQANDSYIHLFNTHLQASYVGAENNVKATVITRVDQLILIKDFIKEQVKKHREK 250 Query: 161 PADVSILAGDLNTAPGDLSYKI 182 +D+ ++ GD N +Y I Sbjct: 251 ESDIIMICGDFNVNARPQTYPI 272 >UniRef50_A6F7A0 Cluster: Putative phospholipase C; n=1; Moritella sp. PE36|Rep: Putative phospholipase C - Moritella sp. PE36 Length = 428 Score = 34.3 bits (75), Expect = 5.8 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 7/74 (9%) Query: 109 KGVGLCRIKFGERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVS-IL 167 +GV RI + +V+ TH + +DD R+ Q EF++ + PAD + IL Sbjct: 269 RGVIYTRINKQGYIYHVFATHTQSS--DDDTNRTARLAQLEEMGEFIREQNIPADEAVIL 326 Query: 168 AGDLNT----APGD 177 AGD N PGD Sbjct: 327 AGDFNVNKIGLPGD 340 >UniRef50_A5ID83 Cluster: Putative uncharacterized protein; n=4; Legionella pneumophila|Rep: Putative uncharacterized protein - Legionella pneumophila (strain Corby) Length = 882 Score = 34.3 bits (75), Expect = 5.8 Identities = 20/74 (27%), Positives = 33/74 (44%) Query: 109 KGVGLCRIKFGERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILA 168 K L R+K +R+I YC H+ +H + ++ + + E V+LT DV IL Sbjct: 447 KYASLVRLKELKRIITQYCDHISWLHHNRTQAIKKQLQEELAKDERVRLTEELNDVEILE 506 Query: 169 GDLNTAPGDLSYKI 182 D + +I Sbjct: 507 KDAEQIKSQILIRI 520 >UniRef50_A4M652 Cluster: DegV family protein; n=1; Petrotoga mobilis SJ95|Rep: DegV family protein - Petrotoga mobilis SJ95 Length = 292 Score = 34.3 bits (75), Expect = 5.8 Identities = 19/73 (26%), Positives = 35/73 (47%) Query: 1 FIINLMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVL 60 F+ ++ ++ + K+ +E IS + + I+C + ++D Y+ E LK L Sbjct: 200 FVNGVVKPIKAVRSRRKSLEEMVNIISDRIKDPKKAIICTRNAICKEDEEYMIEKLKEKL 259 Query: 61 PYSYYFYSGVLGS 73 Y YSG LG+ Sbjct: 260 NYEGEIYSGTLGA 272 >UniRef50_Q332A8 Cluster: Conserved hypothetical phage-related protein; n=1; Clostridium phage c-st|Rep: Conserved hypothetical phage-related protein - Clostridium botulinum C bacteriophage Length = 451 Score = 34.3 bits (75), Expect = 5.8 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 2/71 (2%) Query: 31 LKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQ 90 L S+++ V LQ++ Y+ E KN LP+ + + V L F K +QDVF + Sbjct: 296 LLSKNDFVKLQDIEKNAQKNYVGEEAKNALPFYVHTKTIVFELPLNKF-KQGVQDVFV-K 353 Query: 91 WPLNGYIHKIH 101 +P+NG I I+ Sbjct: 354 FPMNGQITNIN 364 >UniRef50_Q7QTT1 Cluster: GLP_191_17261_17716; n=1; Giardia lamblia ATCC 50803|Rep: GLP_191_17261_17716 - Giardia lamblia ATCC 50803 Length = 151 Score = 34.3 bits (75), Expect = 5.8 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Query: 18 NKKERYEAISTYL--LKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYF-YSGVLGSG 74 N K+ +A+S L KSE + W EK ++ L+ YS+Y S + SG Sbjct: 70 NLKKFMKAMSKNLKKTKSEEEVAA----WQEKVNAWVTGLLEKFDDYSFYLGASNDVESG 125 Query: 75 LCVFSKWVIQDVFFHQW 91 + VF KW D +F+ W Sbjct: 126 MVVFCKWDGADPYFYYW 142 >UniRef50_Q8YVZ6 Cluster: All1820 protein; n=2; Nostocaceae|Rep: All1820 protein - Anabaena sp. (strain PCC 7120) Length = 1009 Score = 33.9 bits (74), Expect = 7.7 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 2/91 (2%) Query: 116 IKFGERLINVYCTHLHAEYHEDDMYLAHRV-LQAYSTAEFVKLTSSPADVSILAG-DLNT 173 I FG+ L N+ T +A + +A V L+ TAEF K T +PA V+++ N+ Sbjct: 592 IAFGQELTNLRQTPANARTAIQEKRIAELVKLEQTITAEFNKFTKTPAVVALVQQLSANS 651 Query: 174 APGDLSYKIISQLPSLLDPYNMKFEGTNPLI 204 +LS + ++ L L N K PL+ Sbjct: 652 GQENLSLRQLNSLRDNLRQLNKKAVLLYPLV 682 >UniRef50_A6CBS1 Cluster: Probable aggregation factor core protein MAFp3, isoform C; n=1; Planctomyces maris DSM 8797|Rep: Probable aggregation factor core protein MAFp3, isoform C - Planctomyces maris DSM 8797 Length = 1133 Score = 33.9 bits (74), Expect = 7.7 Identities = 27/109 (24%), Positives = 41/109 (37%), Gaps = 3/109 (2%) Query: 162 ADVSILAGDLNTAPGDLSYKIISQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDP 221 AD +L + +PG + P+ + PYN+ FE TN + T +N S Sbjct: 807 ADSPVLFARVRFSPGSEDQVSLETEPNSIGPYNLNFEITNSHVELGGNTPVTVNVDLSPG 866 Query: 222 KQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHN 270 + A P D I+ N+ V N +P +SD N Sbjct: 867 ASIYANPFDLNDDDII---NYRDLILFVGLYNTVPSESDSSFAWFSDFN 912 >UniRef50_O96266 Cluster: Putative uncharacterized protein PFB0870w; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein PFB0870w - Plasmodium falciparum (isolate 3D7) Length = 2380 Score = 33.9 bits (74), Expect = 7.7 Identities = 13/28 (46%), Positives = 19/28 (67%) Query: 40 LQEVWSEKDYLYLKENLKNVLPYSYYFY 67 + +W EKDYL+L ENLK++L + Y Sbjct: 880 INNLWIEKDYLFLIENLKDILERKIFDY 907 >UniRef50_A6R9W9 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 330 Score = 33.9 bits (74), Expect = 7.7 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 1/91 (1%) Query: 111 VGLCRIKFGERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGD 170 +G+ R K + V THL + E ++ + +L+ + + IL GD Sbjct: 172 IGVFRNKRTRAMALVMNTHLDHQVSEARLHGSELILKLIGDYKNKRQYKCKLTGVILTGD 231 Query: 171 LNTAPGDLSYKIISQLPSLLDPYNMKFEGTN 201 N+ G +YK+I++ L+DP KF N Sbjct: 232 FNSEEGQEAYKVITESKVLVDPVK-KFGDKN 261 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.320 0.137 0.421 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 464,496,757 Number of Sequences: 1657284 Number of extensions: 20444116 Number of successful extensions: 48261 Number of sequences better than 10.0: 58 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 48162 Number of HSP's gapped (non-prelim): 70 length of query: 404 length of database: 575,637,011 effective HSP length: 102 effective length of query: 302 effective length of database: 406,594,043 effective search space: 122791400986 effective search space used: 122791400986 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 74 (33.9 bits)
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