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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001138-TA|BGIBMGA001138-
PA|IPR005135|Endonuclease/exonuclease/phosphatase
         (404 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000DB7E14 Cluster: PREDICTED: similar to CG12034-PA...   324   2e-87
UniRef50_UPI0000D55DE6 Cluster: PREDICTED: similar to CG12034-PA...   306   7e-82
UniRef50_Q17JK7 Cluster: Neutral Sphingomyelinase, putative; n=1...   302   9e-81
UniRef50_Q9VZS6 Cluster: Putative neutral sphingomyelinase; n=2;...   239   7e-62
UniRef50_A7RL32 Cluster: Predicted protein; n=2; Nematostella ve...   213   7e-54
UniRef50_UPI000069E344 Cluster: Sphingomyelin phosphodiesterase ...   203   6e-51
UniRef50_O45870 Cluster: Putative neutral sphingomyelinase; n=2;...   201   2e-50
UniRef50_O60906 Cluster: Sphingomyelin phosphodiesterase 2; n=17...   199   1e-49
UniRef50_Q4LEU0 Cluster: Mg2+-dependent neutral sphingomyelinase...   198   3e-49
UniRef50_UPI0000E490B9 Cluster: PREDICTED: similar to LD24865p; ...   168   3e-40
UniRef50_A7S570 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ...   154   3e-36
UniRef50_Q5D9I7 Cluster: SJCHGC06222 protein; n=1; Schistosoma j...   149   1e-34
UniRef50_O74369 Cluster: Putative neutral sphingomyelinase; n=3;...   139   1e-31
UniRef50_A4QVL4 Cluster: Putative uncharacterized protein; n=1; ...   134   3e-30
UniRef50_Q6C8M5 Cluster: Yarrowia lipolytica chromosome D of str...   134   4e-30
UniRef50_A1CTA2 Cluster: Sphingomyelinase family protein, putati...   133   7e-30
UniRef50_Q2UM93 Cluster: Sphingomyelinase family protein; n=3; T...   133   9e-30
UniRef50_P40015 Cluster: Inositol phosphosphingolipids phospholi...   132   2e-29
UniRef50_Q4PAL6 Cluster: Putative uncharacterized protein; n=1; ...   125   2e-27
UniRef50_A3LY15 Cluster: Phospholipase C type enzyme; n=5; Sacch...   124   3e-27
UniRef50_Q2HD33 Cluster: Putative uncharacterized protein; n=2; ...   121   4e-26
UniRef50_Q1HG89 Cluster: Inositol phosphorylsphingolipid-phospho...   115   3e-24
UniRef50_A5DP62 Cluster: Putative uncharacterized protein; n=1; ...   110   7e-23
UniRef50_Q4DIM2 Cluster: Putative uncharacterized protein; n=1; ...    93   2e-17
UniRef50_Q4QIE9 Cluster: Putative uncharacterized protein; n=3; ...    90   1e-16
UniRef50_Q57U95 Cluster: Sphingomyelin phosphodiesterase, putati...    82   2e-14
UniRef50_UPI000023DADB Cluster: hypothetical protein FG01057.1; ...    55   4e-06
UniRef50_Q5TEC8 Cluster: Sphingomyelin phosphodiesterase 2, neut...    47   0.001
UniRef50_A0DMK4 Cluster: Chromosome undetermined scaffold_56, wh...    42   0.022
UniRef50_UPI0000F21D16 Cluster: PREDICTED: similar to Mg2+-depen...    42   0.029
UniRef50_Q9NY59 Cluster: Sphingomyelin phosphodiesterase 3; n=22...    41   0.051
UniRef50_Q2SCA2 Cluster: Endonuclease/exonuclease/phophatase fam...    41   0.067
UniRef50_P17627 Cluster: Sphingomyelinase C precursor; n=5; Lept...    40   0.089
UniRef50_A3Y6R9 Cluster: Putative uncharacterized protein; n=1; ...    38   0.36 
UniRef50_Q93HR5 Cluster: Sphingomyelinase; n=2; cellular organis...    37   1.1  
UniRef50_A2QPH4 Cluster: Transposase Tan1-Aspergillus niger; n=3...    36   1.4  
UniRef50_Q5KM82 Cluster: Trehalose-phosphatase, putative; n=2; F...    36   1.9  
UniRef50_A1A5I2 Cluster: Zgc:154063; n=2; Danio rerio|Rep: Zgc:1...    36   2.5  
UniRef50_A0DEC1 Cluster: Chromosome undetermined scaffold_48, wh...    36   2.5  
UniRef50_Q8CVD9 Cluster: Sphingomyelinase C; n=5; Leptospira int...    35   3.3  
UniRef50_Q5AVC8 Cluster: Ferrochelatase; n=9; Fungi/Metazoa grou...    35   3.3  
UniRef50_A7F024 Cluster: Predicted protein; n=1; Sclerotinia scl...    35   3.3  
UniRef50_P59116 Cluster: Sphingomyelinase C 2 precursor; n=6; Le...    35   3.3  
UniRef50_O51552 Cluster: Rep helicase, single-stranded DNA-depen...    35   4.4  
UniRef50_Q9N467 Cluster: Putative uncharacterized protein; n=2; ...    35   4.4  
UniRef50_Q4UHF9 Cluster: Putative uncharacterized protein; n=2; ...    35   4.4  
UniRef50_A7AR39 Cluster: Endonuclease/exonuclease/phosphatase fa...    35   4.4  
UniRef50_P22657 Cluster: RNA replication protein (152 kDa protei...    35   4.4  
UniRef50_UPI00006CF82F Cluster: Endonuclease/Exonuclease/phospha...    34   5.8  
UniRef50_A6F7A0 Cluster: Putative phospholipase C; n=1; Moritell...    34   5.8  
UniRef50_A5ID83 Cluster: Putative uncharacterized protein; n=4; ...    34   5.8  
UniRef50_A4M652 Cluster: DegV family protein; n=1; Petrotoga mob...    34   5.8  
UniRef50_Q332A8 Cluster: Conserved hypothetical phage-related pr...    34   5.8  
UniRef50_Q7QTT1 Cluster: GLP_191_17261_17716; n=1; Giardia lambl...    34   5.8  
UniRef50_Q8YVZ6 Cluster: All1820 protein; n=2; Nostocaceae|Rep: ...    34   7.7  
UniRef50_A6CBS1 Cluster: Probable aggregation factor core protei...    34   7.7  
UniRef50_O96266 Cluster: Putative uncharacterized protein PFB087...    34   7.7  
UniRef50_A6R9W9 Cluster: Predicted protein; n=1; Ajellomyces cap...    34   7.7  

>UniRef50_UPI0000DB7E14 Cluster: PREDICTED: similar to CG12034-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to
           CG12034-PA - Apis mellifera
          Length = 385

 Score =  324 bits (797), Expect = 2e-87
 Identities = 162/397 (40%), Positives = 239/397 (60%), Gaps = 30/397 (7%)

Query: 2   IINLMLL-LRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVL 60
           +IN++ L   GIP VS N+  R  AI+       ++I+CLQE+WS  D+  +K   +  L
Sbjct: 6   LINILTLNCWGIPYVSPNRSARMTAIADKFATENYDIICLQEIWSINDFKMIKAKTQEQL 65

Query: 61  PYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGE 120
           PYS+YFYSGV+GSGLC+ SK+ I+DV FH+WPLNGY+HKIHHGDWFGGKGVGLC+++   
Sbjct: 66  PYSHYFYSGVIGSGLCILSKFPIKDVIFHKWPLNGYVHKIHHGDWFGGKGVGLCKLQIHN 125

Query: 121 RLINVYCTHLHAEYH-EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLS 179
             +NVY  HLHAEY+  +D Y+AHRVLQA+ TA+F+++TS  AD +IL GDLNT P DL 
Sbjct: 126 WNVNVYIAHLHAEYNRHNDEYIAHRVLQAFDTAQFIRMTSGGADSTILGGDLNTEPQDLV 185

Query: 180 YKIISQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFH 239
           Y+II  +  L D  +          +   GT++  NNSY++ K    +P+GKRIDHIL+ 
Sbjct: 186 YRIICGVAGLTDACSNS--------SSNLGTNECANNSYTNTKHANTFPDGKRIDHILYQ 237

Query: 240 TNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESVDSAFQET 299
              + +  ++NF +P P+R+P + FSYSDH A+                  S+D   +++
Sbjct: 238 GTKNVKIEIINFQHPFPNRIPYKNFSYSDHEAIMATFKF------------SID--IKDS 283

Query: 300 ITQAIKVCRDATTNXXXXXXXXXXXXXXIFMFLLGSVGFWPNFLIYDVL------KLLIT 353
           + +AI +C  +  N              + + L+ S+G   +F   DV+      ++ +T
Sbjct: 284 LKEAINICETSLKNVRRQRFWYLLLGCILIIPLIWSIGLDCSFTSLDVIIGLNIGRIFLT 343

Query: 354 ALCFYNLVMGSLWNQIEMNSLKAGLNALENFIQTRND 390
           A+  Y L M S+WN +E N+LKA    +E  ++  N+
Sbjct: 344 AILCYTLFMSSIWNSVEKNALKAACLGMEICLRNLNN 380


>UniRef50_UPI0000D55DE6 Cluster: PREDICTED: similar to CG12034-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG12034-PA - Tribolium castaneum
          Length = 362

 Score =  306 bits (751), Expect = 7e-82
 Identities = 143/323 (44%), Positives = 209/323 (64%), Gaps = 10/323 (3%)

Query: 11  GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70
           G+ VVSKN++ R +AI+  L  S++++VCLQE+W + DY  ++  +  VLPYS+YFYSGV
Sbjct: 12  GLAVVSKNRRHRMQAIAEKLATSQYDVVCLQEIWLDSDYQLIRNKVSGVLPYSHYFYSGV 71

Query: 71  LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130
            GSG+C+ S+  ++DVFFHQWP+NGYIHKIHHGDWFGGKGVGLC++K     +NVY  HL
Sbjct: 72  TGSGVCILSRHPMEDVFFHQWPVNGYIHKIHHGDWFGGKGVGLCKLKVNNYTVNVYSAHL 131

Query: 131 HAEYHED-DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSL 189
           HAEY  + D Y AHRVLQ++ TA+F+++TS  AD+ +LAGDLNT PGDL+Y+I+  +P L
Sbjct: 132 HAEYDRNCDEYQAHRVLQSFDTAQFIQMTSGDADLVVLAGDLNTEPGDLAYRIMLSVPGL 191

Query: 190 LDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEARVV 249
           +D +    E     +A    T+++L NSY+    +K    GKRID+I++H   S +  + 
Sbjct: 192 VDAFGEAGETVQNCVA----TNESLTNSYTPVALLKKNIPGKRIDYIMYHPGSSLQIDLK 247

Query: 250 NFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESVDSAFQETI-TQAIKVCR 308
           ++  PLP ++P   +SYSDH A++  L +     K   R    D   ++T+  ++I++C 
Sbjct: 248 SYTLPLPHKIPGCAYSYSDHEAIAATLIV----TKSEIRSLKSDQHMKKTVLEESIEICD 303

Query: 309 DATTNXXXXXXXXXXXXXXIFMF 331
           DA                 +FMF
Sbjct: 304 DALRGLNNHKYLYWFFTITLFMF 326


>UniRef50_Q17JK7 Cluster: Neutral Sphingomyelinase, putative; n=1;
           Aedes aegypti|Rep: Neutral Sphingomyelinase, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 420

 Score =  302 bits (742), Expect = 9e-81
 Identities = 157/395 (39%), Positives = 230/395 (58%), Gaps = 22/395 (5%)

Query: 5   LMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 64
           L L + GIP VSK++  R EAI   L    ++IV LQEVWS+ DY YLK+ ++ VLP+++
Sbjct: 8   LTLNIWGIPYVSKDRAVRVEAIGDVLSSGNYDIVSLQEVWSDSDYQYLKKRVEGVLPFAH 67

Query: 65  YFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLIN 124
           YFYSGV+GSGL + S++ I    FH W +NGY+H+I HGDWFGGKGVGL +I   ++L+N
Sbjct: 68  YFYSGVVGSGLALLSRYPIVSALFHAWSVNGYVHRIQHGDWFGGKGVGLAKIAVNDQLVN 127

Query: 125 VYCTHLHAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKII 183
           VY  HLHAEY  + D Y+AHRV+QAY TA+F++ T   A + ILAGDLNT PGDL+Y+++
Sbjct: 128 VYAAHLHAEYDRKCDDYMAHRVIQAYDTAQFIESTRGNAVMQILAGDLNTEPGDLAYRVL 187

Query: 184 SQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHS 243
                L+D  + K      L     GT++   NSY+DP+  K YP+GKRID+I++     
Sbjct: 188 QTNAKLIDTADKKLYAAGHL-----GTNEIGRNSYTDPETGKKYPQGKRIDYIMYRIGEH 242

Query: 244 WEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQR----------QESVD 293
           +E R++    PLPDR+P +  SYSDH AV  ++ LK       Q+              D
Sbjct: 243 FEGRLLEHRLPLPDRIPGKDISYSDHEAVYAKIILKKTNSSTIQQLMACGSGEGSHGKCD 302

Query: 294 SAFQETI---TQAIKVCRDATTNXXXXXXXXXXXXXXIFMFLLGSVGFWPNFLI---YDV 347
              QETI    ++I +C ++                 + + LL  +     + +   Y +
Sbjct: 303 YNDQETILALRESIVICNESLKQLDSHKRSYTLMAIGVIIVLLNMLELEAPYGLKSAYLL 362

Query: 348 LKLLITALCFYNLVMGSLWNQIEMNSLKAGLNALE 382
           LK L+     + + M ++WN +E + + AG  ++E
Sbjct: 363 LKFLLCGFVIFFIFMATIWNVMEKHGILAGKLSME 397


>UniRef50_Q9VZS6 Cluster: Putative neutral sphingomyelinase; n=2;
           Sophophora|Rep: Putative neutral sphingomyelinase -
           Drosophila melanogaster (Fruit fly)
          Length = 442

 Score =  239 bits (586), Expect = 7e-62
 Identities = 118/290 (40%), Positives = 179/290 (61%), Gaps = 11/290 (3%)

Query: 5   LMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 64
           L L + GIP VS +++ R +AI   L   +++IV LQEVW+++D   L++  + VLP+S+
Sbjct: 9   LTLNIWGIPYVSSDRRPRIDAICKELASGKYDIVSLQEVWAQEDSELLQKGTEAVLPHSH 68

Query: 65  YFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLIN 124
           YF+SGV+G+GL V SK+ I    FH W +NGY H+I H DWFGGKGVGLCRI  G ++++
Sbjct: 69  YFHSGVMGAGLLVLSKYPILGTLFHAWSVNGYFHRIQHADWFGGKGVGLCRILVGGQMVH 128

Query: 125 VYCTHLHAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKII 183
           +Y  HLHAEY + +D Y  HRV+QA+ TA+F++ T   + + ILAGDLN  P D+SYK++
Sbjct: 129 LYNAHLHAEYDNANDEYKTHRVIQAFDTAQFIEATRGNSALQILAGDLNAQPQDISYKVL 188

Query: 184 SQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHS 243
                +LD  +          + +  T++  +NSY+  +  +  P G RIDHI       
Sbjct: 189 LYTSKMLDSCD----------SDSFRTNECEHNSYTSKQARERNPLGIRIDHIFVRGGDH 238

Query: 244 WEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESVD 293
             A +  +  P P+RVP ++FS+SDH AV  +L L   E +  +   +++
Sbjct: 239 VNAEIAEYKLPFPERVPGEKFSFSDHEAVMAKLKLFKLEPRSEEPVATIE 288


>UniRef50_A7RL32 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 419

 Score =  213 bits (520), Expect = 7e-54
 Identities = 113/285 (39%), Positives = 172/285 (60%), Gaps = 9/285 (3%)

Query: 11  GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70
           GIP +SK  KER+E I+  L   ++++V LQEVW++ DY  + + L + LPYS YFYSGV
Sbjct: 23  GIPFISKQVKERFEHIAKELSTGKYDVVALQEVWNKSDYAVMCDKLSSTLPYSLYFYSGV 82

Query: 71  LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130
           +GSG+CVFS++ I + F +++ LNGY++K+ HGDW  G   G C I    + I+ + +HL
Sbjct: 83  IGSGMCVFSRYRITNSFTYRFSLNGYLYKLWHGDWLAGTSAGYCVIDHPIKPIHFFVSHL 142

Query: 131 HAEYH-EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSL 189
           HAEY+ +DD YLAHRV QAY  A+ ++L + P+D  I+ GD+N+ P DL Y+I+  LP L
Sbjct: 143 HAEYNRQDDEYLAHRVTQAYQFAQLIELITKPSDCVIVCGDMNSEPTDLCYRILCNLPGL 202

Query: 190 LDPY-NMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYP-EGKRIDHILFHTNHSWEAR 247
            D +     EG +       G S N     +  + ++  P +G RID+I +  + S    
Sbjct: 203 TDTWLECNKEGYH---GNTYGVSHNSFAGSTFQQAIQKGPSDGIRIDYIFYRGDRS-NME 258

Query: 248 VVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESV 292
           +++  +    R+P ++ SYSDH  V     LK  ++ L + QE V
Sbjct: 259 LLDC-HVTMSRIPWEEISYSDHEGVLATFCLKN-DKVLEKGQEKV 301


>UniRef50_UPI000069E344 Cluster: Sphingomyelin phosphodiesterase 2
           (EC 3.1.4.12) (Neutral sphingomyelinase) (nSMase)
           (N-SMase) (Lyso-platelet-activating factor-
           phospholipase C) (Lyso-PAF-PLC).; n=2; Xenopus
           tropicalis|Rep: Sphingomyelin phosphodiesterase 2 (EC
           3.1.4.12) (Neutral sphingomyelinase) (nSMase) (N-SMase)
           (Lyso-platelet-activating factor- phospholipase C)
           (Lyso-PAF-PLC). - Xenopus tropicalis
          Length = 341

 Score =  203 bits (496), Expect = 6e-51
 Identities = 99/225 (44%), Positives = 149/225 (66%), Gaps = 5/225 (2%)

Query: 15  VSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGVLGSG 74
           +SK +KER   I   L +  +++  LQE+WS+KDY  L+  L +V PY++ F SGV+GSG
Sbjct: 22  LSKKRKERLALIGQLLSQQCYDLALLQEIWSDKDYSELRHRLSDVFPYTHRFKSGVIGSG 81

Query: 75  LCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHLHAEY 134
           LCVFS++ I D   +Q+ LNG+ + ++HGDWF GK VGL ++K    L +VY THLHAEY
Sbjct: 82  LCVFSQFPIIDCLQYQFSLNGFPYMMNHGDWFCGKAVGLVKLKAYGFLCHVYVTHLHAEY 141

Query: 135 -HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPY 193
             E+D Y +HR+LQ++  A+F++ TS+ +DV +LAGDLN  PGDL  K++ +   L D Y
Sbjct: 142 CRENDCYRSHRILQSWELAQFIRHTSNNSDVVVLAGDLNMHPGDLGVKLVREWTGLKDSY 201

Query: 194 NMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILF 238
               E   P      G +   +N ++DP+++K +P+G RID+I++
Sbjct: 202 LECTEYEGP----PDGCTLIPSNPFTDPQELKNFPQGIRIDYIMY 242


>UniRef50_O45870 Cluster: Putative neutral sphingomyelinase; n=2;
           Caenorhabditis|Rep: Putative neutral sphingomyelinase -
           Caenorhabditis elegans
          Length = 434

 Score =  201 bits (491), Expect = 2e-50
 Identities = 126/395 (31%), Positives = 203/395 (51%), Gaps = 18/395 (4%)

Query: 3   INLMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPY 62
           +N   L +  P+ S ++  R   I  Y++   ++IV LQE+WS  D++ L E + +V PY
Sbjct: 44  LNAWCLPQPWPIGSTDRVHRLNKIGQYMIDELYDIVGLQELWSYYDFVRLSEQVSSVYPY 103

Query: 63  SYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF-GER 121
            +YF+SG  GSG+CVFS+  I     +++ LNG+ H IH GDWFGGK VGL  I+  G+ 
Sbjct: 104 FHYFHSGFTGSGVCVFSRHPIVSTLTNRYSLNGFAHHIHRGDWFGGKVVGLTEIEIDGDL 163

Query: 122 LINVYCTHLHAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSY 180
            +N Y THLHAEY  E+D+YL HR  QA+  A+FV+ T+  ADV I+ GDLN  P DL +
Sbjct: 164 RVNFYTTHLHAEYDRENDLYLPHRTAQAFELAQFVRHTARGADVVIVTGDLNMEPCDLGF 223

Query: 181 KIISQLPSLLDPYNMKFEGTNP----------LIAKASGTSDNLNNSYSDPKQVKAYPEG 230
           ++I     L D + M  E  N            IAK  GT D  +N Y+  + +K   + 
Sbjct: 224 RLILSHAKLFDAWRMSHEVENEDSEGELLKFRGIAK-GGTCDRPDNCYT-KRALKNVDDS 281

Query: 231 KRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQE 290
           KRID++LF +      ++      L +++P +  +YSDH  V L       ++  +++  
Sbjct: 282 KRIDYMLFKSGRC-NVKLEECEITL-NQIPGEDLNYSDH--VGLRARFTIDDRFRHEKSV 337

Query: 291 SVDSAFQETITQAIKVCRDATTNXXXXXXXXXXXXXXIFMFLLGSVGFWPNFLIYDVLKL 350
           +     +  + +AI +                       + +LGS+ F    + + VL+ 
Sbjct: 338 NTWEPNRPLLIEAIGLVAGGERRARTDRIFFFILAVICLILILGSLFFEVFPMGFAVLRF 397

Query: 351 LITALCFYNLVMGSLWNQIEMNSLKAGLNALENFI 385
            +T +  + +  G +   +E  +LKA   A++  +
Sbjct: 398 ALTVVGVFFVWQGLIGLTLERKALKAAKQAIQQIL 432


>UniRef50_O60906 Cluster: Sphingomyelin phosphodiesterase 2; n=17;
           Amniota|Rep: Sphingomyelin phosphodiesterase 2 - Homo
           sapiens (Human)
          Length = 423

 Score =  199 bits (485), Expect = 1e-49
 Identities = 104/270 (38%), Positives = 153/270 (56%), Gaps = 6/270 (2%)

Query: 11  GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70
           GIP +SK++ +R   +  +L +   ++  L+EVWSE+D+ YL++ L    P +++F SG+
Sbjct: 18  GIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYPAAHHFRSGI 77

Query: 71  LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130
           +GSGLCVFSK  IQ++  H + LNGY + IHHGDWF GK VGL  +     ++N Y THL
Sbjct: 78  IGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHL 137

Query: 131 HAEYH-EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSL 189
           HAEY+ + D+YLAHRV QA+  A+F+  TS  ADV +L GDLN  P DL   ++ +   L
Sbjct: 138 HAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGL 197

Query: 190 LDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEARVV 249
            D Y    E T        G +    N Y   +++K +P G RID++L+     +     
Sbjct: 198 HDAY---LE-TRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCK 253

Query: 250 NFGNPLPDRVPEQQFSYSDHNAVSLELHLK 279
           +F        P      SDH A+   L ++
Sbjct: 254 SF-ETTTGFDPHSGTPLSDHEALMATLFVR 282


>UniRef50_Q4LEU0 Cluster: Mg2+-dependent neutral sphingomyelinase;
           n=7; Clupeocephala|Rep: Mg2+-dependent neutral
           sphingomyelinase - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 420

 Score =  198 bits (482), Expect = 3e-49
 Identities = 109/271 (40%), Positives = 155/271 (57%), Gaps = 10/271 (3%)

Query: 11  GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70
           GI  +SK   +RYE I   L + +H+I  LQEVWSE+D+L+LK  L    PY++YF SGV
Sbjct: 18  GIRFLSKLCAQRYEMIGELLGREQHDIALLQEVWSERDFLFLKRKLSCSHPYTHYFKSGV 77

Query: 71  LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130
           +GSGL VFSK  IQD   +Q+ LNGY + + HGDWFGGK  GL  ++      +VY THL
Sbjct: 78  IGSGLAVFSKHRIQDALLYQYSLNGYPYMLSHGDWFGGKAAGLVIVEVFGLKAHVYVTHL 137

Query: 131 HAEY-HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSL 189
           HAEY    D YL HR++Q++   +FV+ TS  AD+ IL GDLN  P DL  +++     L
Sbjct: 138 HAEYSRAQDGYLPHRIVQSWELQQFVRHTSHGADLVILGGDLNMHPSDLGNRLLRSHTGL 197

Query: 190 LDPYNM--KFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEAR 247
              Y    KF+G         G +   NN ++  + +  + +G RID+IL   +     +
Sbjct: 198 RGCYTETDKFDGCE------DGHTLIANNHFTKKQDLIPFEKGIRIDYILMKGSQRVSVK 251

Query: 248 VVNFGNPLPDRVPEQQFSYSDHNAVSLELHL 278
             +  +     V ++ F YSDH A+  +L+L
Sbjct: 252 CESL-STTKGSVSDKPFPYSDHEALMADLNL 281


>UniRef50_UPI0000E490B9 Cluster: PREDICTED: similar to LD24865p;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to LD24865p - Strongylocentrotus purpuratus
          Length = 212

 Score =  168 bits (408), Expect = 3e-40
 Identities = 81/192 (42%), Positives = 116/192 (60%), Gaps = 6/192 (3%)

Query: 11  GIPV-VSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSG 69
           G+P  VSK++ ER + I+  L    ++IV LQE+W  +DY  +K  ++ VLP+S+YF  G
Sbjct: 12  GLPFGVSKHRSERMQHIAKELASGAYDIVSLQEIWVMEDYQLIKSTVEKVLPHSFYFRMG 71

Query: 70  VLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTH 129
           +L  GLC+FSKW I D F+H + LNGY HK+   DW+  K V LC++      +NVY TH
Sbjct: 72  MLHGGLCIFSKWPIIDTFYHPYSLNGYAHKVTMADWYISKMVALCKLDVEGMTVNVYNTH 131

Query: 130 LHAEY-----HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIIS 184
            HA Y      E D +L HR+ Q Y  +EFV+LTS  AD+ ++ GD N+ P  L+ K+  
Sbjct: 132 AHALYAPSNIPEKDEFLTHRLTQLYELSEFVRLTSGAADLVLVTGDFNSEPFSLATKLAV 191

Query: 185 QLPSLLDPYNMK 196
               LLD +  +
Sbjct: 192 SNARLLDAWETR 203


>UniRef50_A7S570 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
           Predicted protein - Nematostella vectensis
          Length = 163

 Score =  154 bits (374), Expect = 3e-36
 Identities = 75/146 (51%), Positives = 100/146 (68%), Gaps = 6/146 (4%)

Query: 11  GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70
           GIP +SK  KER+  I+  L   +++IV LQEVWS+ DY  L+ N+   LP+S YFYSGV
Sbjct: 23  GIPFISKQVKERFGHIAKELASGKYDIVSLQEVWSKADYDVLRSNVSKTLPHSMYFYSGV 82

Query: 71  LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHL 130
                CVFS++ I + F +++ LNGY++KI HGDWFGGK  G C I    R I+ + THL
Sbjct: 83  -----CVFSRYPIIESFTYRYTLNGYMYKIAHGDWFGGKSSGYCVIDHPLRPIHFFTTHL 137

Query: 131 HAEYH-EDDMYLAHRVLQAYSTAEFV 155
           HAEY+ ++D YLAHRV QAY  A+F+
Sbjct: 138 HAEYNRKNDEYLAHRVTQAYQLAQFI 163


>UniRef50_Q5D9I7 Cluster: SJCHGC06222 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC06222 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 213

 Score =  149 bits (362), Expect = 1e-34
 Identities = 73/185 (39%), Positives = 107/185 (57%), Gaps = 4/185 (2%)

Query: 13  PVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGVLG 72
           P  +  K++R  AI++ L   + +++ LQE+W E DY  L+  L +  PYS YFY  ++G
Sbjct: 19  PSSTVRKEDRVNAIASKLANGDFDVILLQEIWLESDYRKLRLLLDDKYPYSNYFYCNLIG 78

Query: 73  SGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERL-INVYCTHLH 131
           +G+C+FSKW+I+ VF H +  NGY H IH  D++ GKG+GL RI   E   IN Y THL 
Sbjct: 79  TGMCIFSKWIIECVFTHPFTTNGYPHLIHQADYYCGKGIGLARITSKEGFRINFYVTHLI 138

Query: 132 AEYHED---DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPS 188
           A Y  D   D Y  HR+ Q     EFV++TS+ +D  I+ GD N      + +++     
Sbjct: 139 ARYELDRMLDKYNGHRISQLVEVMEFVRMTSTGSDAIIITGDFNLESNTSAIELLCTSLK 198

Query: 189 LLDPY 193
           L D +
Sbjct: 199 LSDAW 203


>UniRef50_O74369 Cluster: Putative neutral sphingomyelinase; n=3;
           Schizosaccharomyces pombe|Rep: Putative neutral
           sphingomyelinase - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 424

 Score =  139 bits (337), Expect = 1e-31
 Identities = 92/285 (32%), Positives = 149/285 (52%), Gaps = 19/285 (6%)

Query: 11  GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70
           G+  VSK + ER +A+   L K +++IV LQEVWS  D+  ++  +   L YS +F+S  
Sbjct: 18  GLRFVSKYRTERLKAVGEKLAKCDYDIVLLQEVWSIYDFQEIRNLVSCNLVYSRFFHSAA 77

Query: 71  LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF-GERLINVYCTH 129
           +G+GL +FSK+ I +   +++PLNG       GDW+ GKGV    ++    R+I+++ TH
Sbjct: 78  MGAGLAMFSKFPIIESSMNKYPLNGRPQAFWRGDWYVGKGVATASLQHPSGRIISLFNTH 137

Query: 130 LHAEYHED-DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPS 188
           LHA Y +  D YL HR+ QA+  ++ ++       + I AGD N  P  + ++II+    
Sbjct: 138 LHAPYGKGADTYLCHRLSQAWYISKLLRAAVQRGHIVIAAGDFNIQPLSVPHEIITSYGL 197

Query: 189 LLD------------PYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPE--GKRID 234
           + D            P N        L+  A  T D+  N++ +    K   +   KR+D
Sbjct: 198 VNDAWLSVYPDQVEHPPNRFSMNDKELVEIAGTTCDSRLNTWRENISSKDMDDFVAKRLD 257

Query: 235 HILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLK 279
           ++ FH+  + EA+  N      +RVP+   SYSDH A+   L +K
Sbjct: 258 YV-FHSPSTCEAK--NAKVVFLERVPKLDCSYSDHFAIETVLSIK 299


>UniRef50_A4QVL4 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 649

 Score =  134 bits (325), Expect = 3e-30
 Identities = 72/201 (35%), Positives = 111/201 (55%), Gaps = 6/201 (2%)

Query: 3   INLMLL-LRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLP 61
           IN++ L   G+  VSK + ER   I   L  +   IV LQEVWSE+DY  L+   + VLP
Sbjct: 6   INIVTLNCWGLRFVSKWRSERILEIGRRLSTTAPGIVALQEVWSEEDYEILRRETRAVLP 65

Query: 62  YSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG-- 119
           Y   +++GV GSGL + S+W +++    Q+PLNG       GDW+ GKGV   RI++G  
Sbjct: 66  YGKQYHAGVFGSGLVILSRWPLEESSMFQFPLNGRPTAFFRGDWYAGKGVAHARIRYGPQ 125

Query: 120 -ERLINVYCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPG 176
             ++I V+  H HA Y  +  D Y AHR  QA+  A+ ++  S    + +  GDLN  P 
Sbjct: 126 KSQVIEVFNIHTHAAYETEAKDSYAAHRASQAWFFAKLLRSASERGHLVVGLGDLNAPPF 185

Query: 177 DLSYKIISQLPSLLDPYNMKF 197
            L +++++    + D + + +
Sbjct: 186 SLPHRLVTAQAPVRDAWRVLY 206


>UniRef50_Q6C8M5 Cluster: Yarrowia lipolytica chromosome D of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome D of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 454

 Score =  134 bits (324), Expect = 4e-30
 Identities = 93/297 (31%), Positives = 147/297 (49%), Gaps = 25/297 (8%)

Query: 11  GIPVVSKNKKERYEAISTYLLKS--EHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYS 68
           G+ +VSK +  R EAIS  L +    ++IVCLQEVW E D+  +K+   +  PY+ Y+YS
Sbjct: 60  GLKLVSKLRPLRLEAISAQLAQDGDSYDIVCLQEVWVESDFDQIKKACVDHFPYTKYYYS 119

Query: 69  GVL-GSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF-GERLINVY 126
           G++ G GL V S+W I+  + H++ LNG       GDW+ GK V    I       I + 
Sbjct: 120 GIIAGPGLAVLSRWPIESAYVHRFGLNGRPSAFFRGDWYVGKSVASATIIHPSNHRIEIL 179

Query: 127 CTHLHAEYHEDDM-YLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQ 185
             H+HA Y   D  Y  HR  QA+  A   K +    +++I+ GDLN+ P  L++++   
Sbjct: 180 NAHMHAPYGPGDANYTCHRTSQAWEMARIAKRSMDAGNLTIVTGDLNSRPSSLTHQLFEN 239

Query: 186 LPSLLDPYNMK---FEG------TNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHI 236
           +  L D +  +   F G          I +A  T ++  NS+   +  +   +  R+D+I
Sbjct: 240 MALLQDAWESRHGEFSGDLSEMTPEQQIEEAGVTCNSRLNSW---RASRPLSDACRLDYI 296

Query: 237 LFHTNHSW--EARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQES 291
            F  + +   EARV        D++ E   S SDH  VS    L P ++  +++  S
Sbjct: 297 FFDPSRATVREARVA-----FTDKI-EGGCSVSDHFGVSAVFELTPQDKSRHRKVSS 347


>UniRef50_A1CTA2 Cluster: Sphingomyelinase family protein, putative;
           n=9; Pezizomycotina|Rep: Sphingomyelinase family
           protein, putative - Aspergillus clavatus
          Length = 482

 Score =  133 bits (322), Expect = 7e-30
 Identities = 64/180 (35%), Positives = 102/180 (56%), Gaps = 7/180 (3%)

Query: 11  GIPVVSKNKKERYEAISTYLLKSEH--NIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYS 68
           G+  +SK + ER   I   L  ++    IV LQE W+++DY  +++  +++LPY  +++ 
Sbjct: 27  GLKYISKFRHERMSEIGRQLAIADPPPQIVGLQECWTQQDYESIRQQTRDILPYGKFYFG 86

Query: 69  GVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG---ERLINV 125
           G+ G+GL + SKW I++     +PLNG       GDWF GKGV   RI+FG   + +  V
Sbjct: 87  GIFGAGLAILSKWPIEESSMFAYPLNGRPTAFFRGDWFVGKGVACARIRFGPAAQDVAEV 146

Query: 126 YCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKII 183
           +CTHLHA Y  +  D YL HR  QA+  A+ ++  +    + I  GD N  P   ++++I
Sbjct: 147 FCTHLHAPYEREPHDSYLCHRTAQAWEIAKLMRGAAERGHLVIGLGDFNMIPSSFAHRLI 206


>UniRef50_Q2UM93 Cluster: Sphingomyelinase family protein; n=3;
           Trichocomaceae|Rep: Sphingomyelinase family protein -
           Aspergillus oryzae
          Length = 476

 Score =  133 bits (321), Expect = 9e-30
 Identities = 62/180 (34%), Positives = 105/180 (58%), Gaps = 7/180 (3%)

Query: 11  GIPVVSKNKKERYEAISTYLLKSEH--NIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYS 68
           G+  ++K + ER   I   L  ++    IV LQE W+++DY  ++E  +++LPY  +++ 
Sbjct: 25  GLKYLAKYRHERLSEIGRQLALADPAPEIVGLQECWTQQDYESIREQTRHLLPYGKFYFG 84

Query: 69  GVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG---ERLINV 125
           GV+G+GL + SKW I++   + +PLNG       GDW+ GKGV   R++FG     +  V
Sbjct: 85  GVMGAGLAILSKWPIEESSMYGYPLNGRPTAFFRGDWYVGKGVACARVRFGPGASDVAEV 144

Query: 126 YCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKII 183
           +CTHLHA Y ++  D Y+ HR  QA+  A+ ++  +    ++I  GD N  P   ++++I
Sbjct: 145 FCTHLHAPYEKEPNDSYICHRTAQAWEIAKLMRGAAERGHLAIGLGDFNMVPSSFAHQLI 204


>UniRef50_P40015 Cluster: Inositol phosphosphingolipids
           phospholipase C; n=7; Saccharomycetales|Rep: Inositol
           phosphosphingolipids phospholipase C - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 477

 Score =  132 bits (318), Expect = 2e-29
 Identities = 80/260 (30%), Positives = 131/260 (50%), Gaps = 19/260 (7%)

Query: 34  EHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGVL-GSGLCVFSKWVIQDVFFHQWP 92
           +++++ LQE+W  +D+ YL     +  PY   F+SG+L G GL + SK  I+  F +++P
Sbjct: 92  DYDVIALQEIWCVEDWKYLASACASKYPYQRLFHSGILTGPGLAILSKVPIESTFLYRFP 151

Query: 93  LNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHLHAEYHE--DDMYLAHRVLQAYS 150
           +NG    +  GDW+ GK + +  +  G R I +  +H+HA Y +  D  YL HR  QA+ 
Sbjct: 152 INGRPSAVFRGDWYVGKSIAITVLNTGTRPIAIMNSHMHAPYAKQGDAAYLCHRSCQAWD 211

Query: 151 TAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPYNM--------KFEGTNP 202
            +  +KL        I+ GDLN+ PG L +K ++Q   L+D +               +P
Sbjct: 212 FSRLIKLYRQAGYAVIVVGDLNSRPGSLPHKFLTQEAGLVDSWEQLHGKQDLAVIARLSP 271

Query: 203 L--IAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVP 260
           L  + K   T D+L N++   +Q     E  R+D+ L   +     + V+ G    +R+P
Sbjct: 272 LQQLLKGCTTCDSLLNTWRAQRQP---DEACRLDYALIDPDF---LQTVDAGVRFTERIP 325

Query: 261 EQQFSYSDHNAVSLELHLKP 280
               S SDH A S  L++ P
Sbjct: 326 HLDCSVSDHFAYSCTLNIVP 345


>UniRef50_Q4PAL6 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 525

 Score =  125 bits (301), Expect = 2e-27
 Identities = 85/261 (32%), Positives = 130/261 (49%), Gaps = 12/261 (4%)

Query: 5   LMLLLRGIPVVSKNKKERYEAISTYLLKSE---HNIVCLQEVWSE-KDYLYLKENLKNVL 60
           L L + G+  +SK +  R +AI++ L  S+   ++ VCLQE+W E +D+ +LK  L +  
Sbjct: 42  LTLNVWGLKYISKLRIARIKAIASRLASSDMPLYDFVCLQEIWYESRDWRFLKHALSSRY 101

Query: 61  PYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGE 120
           P+S +FYSG  GSGL + S+W I +   H + LNG    +HHGDWF GK  G   I    
Sbjct: 102 PHSKFFYSGAFGSGLAILSRWNILETRTHPYSLNGQPIHVHHGDWFVGKACGSVTINHPR 161

Query: 121 -RLINVYCTHLHAEYHED--DMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGD 177
             L++V+ TH  A   ED  +   +HR+ QAY  A   + ++S     +  GDLN+ P  
Sbjct: 162 LGLVDVWNTHFVAAGGEDGPEYKRSHRITQAYELAANCRNSASKGRHVVCVGDLNSTPPS 221

Query: 178 LSYKIISQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDPKQVKAYPEGKRIDHIL 237
           L+  ++  +  L D     F  T P + + + + D    S     +  A P+ +R    L
Sbjct: 222 LAIGLLRHIGGLYD----SFLDTRPQLPEHAVSLDPEETSTQVGDRATAAPDPQRAIEEL 277

Query: 238 FHTNHSWEARVVNFGNPLPDR 258
             T  S        G PL +R
Sbjct: 278 GVTCDS-PLNTWTAGKPLDER 297


>UniRef50_A3LY15 Cluster: Phospholipase C type enzyme; n=5;
           Saccharomycetales|Rep: Phospholipase C type enzyme -
           Pichia stipitis (Yeast)
          Length = 442

 Score =  124 bits (300), Expect = 3e-27
 Identities = 91/301 (30%), Positives = 145/301 (48%), Gaps = 31/301 (10%)

Query: 11  GIPVVSKNKKERYEAISTYLL-----KSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYY 65
           G+  +SK +++R  AI+  L        E++IV LQEVW E D+ YL    K V PY   
Sbjct: 34  GLKYISKFRRQRLRAIANKLAYPATKDDEYDIVALQEVWCEDDWKYLDGTCKKVYPYRRV 93

Query: 66  FYSGVL-GSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF---GER 121
           F SG++ G GL + SK  I + F +++P+NG       GDW  GK + +  +K    G  
Sbjct: 94  FKSGIVTGPGLVLLSKIPIDESFLYRFPINGRASAFFRGDWLVGKSIAITLLKPHQPGAM 153

Query: 122 LINVYCTHLHAEYHE--DDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLS 179
            I +  +H+HA Y +  ++ Y  HR  QA+  A+ VK+        I  GDLN+ PG L 
Sbjct: 154 PIALLNSHMHAPYAQSGENSYSTHRACQAWDFAKLVKMLRRSGYAVIQVGDLNSKPGSLP 213

Query: 180 YKIISQLPSLLDPYNMKFEGTNPL-------------IAKASGTSDNLNNSYSDPKQVKA 226
           YK+ +    L D +++ ++  + L             I KA  T +N  N++     ++ 
Sbjct: 214 YKLFTVEGGLSDSWDLCYDKESQLTIEDLAAMQPLEQIHKAGTTVNNQLNTWRAHSDIR- 272

Query: 227 YPEGKRIDHILFHT-NHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQKL 285
             +  R+D+ L    N    +  V F   LP   P    S+SDH   + EL ++   ++L
Sbjct: 273 --DACRLDYALIDAHNIKPISAAVKFTEKLP---PPYNCSFSDHFGYTAELQIRSDGEEL 327

Query: 286 N 286
           +
Sbjct: 328 D 328


>UniRef50_Q2HD33 Cluster: Putative uncharacterized protein; n=2;
           Sordariales|Rep: Putative uncharacterized protein -
           Chaetomium globosum (Soil fungus)
          Length = 574

 Score =  121 bits (291), Expect = 4e-26
 Identities = 61/198 (30%), Positives = 111/198 (56%), Gaps = 9/198 (4%)

Query: 3   INLMLL-LRGIPVVSKNKKERYEAISTYLLKS--EHNIVCLQEVWSEKDYLYLKENLKNV 59
           INL+ L   G+  +SK ++ER   I   L  +  + +IV LQE ++++DY  ++  ++ +
Sbjct: 8   INLVTLNCWGLKYISKLRRERLTEIGRQLATASPQPHIVALQECFTQEDYQSIRHEVRFI 67

Query: 60  LPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG 119
           LPY  +++S   G GL + S+W I++   +++PLNG       GDW+ GKG+   +I++G
Sbjct: 68  LPYGKFYHSAAFGGGLAILSRWPIEESTMYRYPLNGRPTAFWRGDWYVGKGIACAKIRYG 127

Query: 120 ---ERLINVYCTHLHAEYH---EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNT 173
              ++++ V+ TH HA Y     +D YL HR  Q++  A+ ++  +    + +  GD N 
Sbjct: 128 PAAKQVVEVFNTHTHAPYEGGKPNDSYLCHRTAQSWEMAKLLRGAAERGHLVLAMGDFNM 187

Query: 174 APGDLSYKIISQLPSLLD 191
            P    Y++I+ L  + D
Sbjct: 188 IPMSREYQLITGLAPVSD 205


>UniRef50_Q1HG89 Cluster: Inositol
           phosphorylsphingolipid-phospholipase C; n=3;
           Filobasidiella neoformans|Rep: Inositol
           phosphorylsphingolipid-phospholipase C - Cryptococcus
           neoformans var. grubii (Filobasidiella neoformans
           var.grubii)
          Length = 529

 Score =  115 bits (276), Expect = 3e-24
 Identities = 75/245 (30%), Positives = 126/245 (51%), Gaps = 19/245 (7%)

Query: 11  GIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGV 70
           G+ +V+KN+  R  AI+ YL  S ++IVCLQE+W  KDY  ++E ++  LP+S +F++G 
Sbjct: 23  GLAIVAKNRHTRIHAIAEYLASSNYDIVCLQELWIYKDYEVVREEVQRNLPFSRFFHTGA 82

Query: 71  LGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGK---GVGLCRIKFGERLINVYC 127
           LGSGL +F+++ +       + L+G   +   GD+F  K    V +     GE  + ++ 
Sbjct: 83  LGSGLAIFTRFPLIAAHALPYSLSGSPAQAFAGDFFVKKAAANVVILHPVLGE--VEIWN 140

Query: 128 THLHAE-YHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQL 186
           TH+HA   H  D   AHR+ Q++  A  V+  ++      + GD N+ P  +   ++   
Sbjct: 141 THMHAAGEHPPDTRQAHRIAQSWQLANAVRGGAAKGRYVFVMGDFNSQPWSIPIAMMRDH 200

Query: 187 PSLLDPYNMKFEGTNPLIA---------KASG-TSDNLNNSYSDPKQVKAY---PEGKRI 233
             L+D ++      N  I+         K  G T D+  N+YS  K +  +     GKR+
Sbjct: 201 AQLMDSFDQVHPSANSEISPPPSPAEALKVYGMTCDSPLNTYSAGKPIPEHVLEKGGKRL 260

Query: 234 DHILF 238
           D+I F
Sbjct: 261 DYIFF 265


>UniRef50_A5DP62 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 468

 Score =  110 bits (264), Expect = 7e-23
 Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 12/197 (6%)

Query: 11  GIPVVSKNKKERYEAISTYLLKS------EHNIVCLQEVWSEKDYLYLKENLKNVLPYSY 64
           G+  VSK ++ R  AI+  L  +      +++IV LQEVW  +D+ YL    +N+ PY  
Sbjct: 35  GLKYVSKYRRFRLCAIADRLANAVPGSQDDYDIVALQEVWCSEDWEYLSSRCENLYPYRR 94

Query: 65  YFYSGVL-GSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIK---FGE 120
            F SG++ G GLC+ SK  I++ F +++P+NG       GDW  GK + +  ++    G 
Sbjct: 95  NFNSGIITGPGLCILSKVPIKETFLYRFPINGRPSAFFRGDWMVGKSISVTLLQPHTKGA 154

Query: 121 RLINVYCTHLHAEY--HEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDL 178
             I +  +H+HA Y    D  Y  HR  QA+   + V++        +  GDLN+ PG L
Sbjct: 155 LPIALLNSHMHAPYALTGDAAYSCHRACQAWDFTKLVRMLKRAGYAVVQVGDLNSRPGSL 214

Query: 179 SYKIISQLPSLLDPYNM 195
            YK+ +    L D +++
Sbjct: 215 PYKLFTVEGGLEDSWDV 231


>UniRef50_Q4DIM2 Cluster: Putative uncharacterized protein; n=1;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 597

 Score = 92.7 bits (220), Expect = 2e-17
 Identities = 89/285 (31%), Positives = 130/285 (45%), Gaps = 43/285 (15%)

Query: 18  NKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENLKNVLPYSYYFY---SGVLGS 73
           N K R   ++ +  K  H +I+ LQE +S++D+  +  NL + +    YF    S   GS
Sbjct: 17  NSKYRAARMARFAAKVAHYDIILLQEQFSKEDFELIISNLPSEVREKRYFKRFPSAFYGS 76

Query: 74  GLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG---ERLIN------ 124
           G+ V S++ I+   F  +PL GY  ++ HGD++  KG  L RI       R ++      
Sbjct: 77  GIAVISRFPIKSALFFTFPLQGYPERVLHGDYYANKGASLLRIHVPCTTRRGVSPDPPYE 136

Query: 125 ---VYCTHLHAEYHE--------DDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNT 173
              +Y THL A Y +        D++YL  R+ QA S AEF+  TS P D  I+ GD N 
Sbjct: 137 DVLLYNTHLVAAYQKTARLLNWRDELYLPVRLSQAISLAEFISSTSHPTDRVIIGGDFNA 196

Query: 174 APGDL------------SYKIISQLPSLLDPYNMKFEGTNPLIAKASGT-SD-NLNNSYS 219
               L             YK++S LP  +  Y  +       I  A+ T SD N+ NS  
Sbjct: 197 TQRSLELQAMLILLRKRGYKLVSVLPPSI-MYRPEMSEREKRINTATLTYSDANMFNSPK 255

Query: 220 DPKQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQF 264
           D   V+      +IDHI F +N     R+  F N  PD   +  F
Sbjct: 256 DGWFVEGGDVPCQIDHIFFTSN---TLRLSAF-NDCPDAAADYPF 296


>UniRef50_Q4QIE9 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 653

 Score = 89.8 bits (213), Expect = 1e-16
 Identities = 58/188 (30%), Positives = 91/188 (48%), Gaps = 22/188 (11%)

Query: 18  NKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENLKNVLPYSYYFY---SGVLGS 73
           N + R   +  +  K EH +++ LQE +S +D+  + +N   V+  +Y F    S   GS
Sbjct: 26  NSRMREARMKVFATKIEHYDVILLQEQFSVEDFDLIFQNASPVVQRTYTFRRFCSSFYGS 85

Query: 74  GLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERL----------I 123
           G  V S++ I   FFH +PL GY   + HGD+F  KG  + R+     +          +
Sbjct: 86  GCAVISRYPISQAFFHTFPLQGYPEMVLHGDFFANKGAAMVRVMVPVTMADGGAAKAQEV 145

Query: 124 NVYCTHLHAEYHE--------DDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAP 175
            +Y THL A Y +         + YL  R+ QA S A+F+  TS P D  I+ GD N + 
Sbjct: 146 TLYTTHLVAVYEKVSQLSSWRRERYLPFRISQAISFADFIVSTSRPTDPIIIGGDFNCSQ 205

Query: 176 GDLSYKII 183
             L  +++
Sbjct: 206 RSLEVQMM 213


>UniRef50_Q57U95 Cluster: Sphingomyelin phosphodiesterase, putative;
           n=1; Trypanosoma brucei|Rep: Sphingomyelin
           phosphodiesterase, putative - Trypanosoma brucei
          Length = 580

 Score = 82.2 bits (194), Expect = 2e-14
 Identities = 59/181 (32%), Positives = 93/181 (51%), Gaps = 25/181 (13%)

Query: 18  NKKERYEAISTYLLKSE-HNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFY---SGVLGS 73
           N K R E ++ +  K E ++I+ LQE +SE D+  + +N+   +  + YF    +   GS
Sbjct: 17  NSKHRPERMAHFASKVEDYDIILLQEQFSESDFDIIIQNMPEEVRRTRYFKRYPTAFYGS 76

Query: 74  GLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVG-LC---------RIKFGE--- 120
           G+ V S++ ++   F  +PL G+  ++ HGD++  KG   LC          +  G    
Sbjct: 77  GIAVISRFPVKSGVFFTFPLQGFPEQVLHGDYYANKGAAMLCVSVPCNNDVEVSGGSVMH 136

Query: 121 RLINVYCTHLHAEYH--------EDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLN 172
           R + VY THL A Y          D++YLA R+ QA S A F+  TS+P D  I+ GD N
Sbjct: 137 RDVLVYSTHLVAVYQVPSQLRDWRDEVYLAVRLSQAISFANFIIATSNPTDHIIIGGDFN 196

Query: 173 T 173
           +
Sbjct: 197 S 197


>UniRef50_UPI000023DADB Cluster: hypothetical protein FG01057.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG01057.1 - Gibberella zeae PH-1
          Length = 476

 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 26/87 (29%), Positives = 49/87 (56%), Gaps = 3/87 (3%)

Query: 3   INLMLL-LRGIPVVSKNKKERYEAISTYLLKS--EHNIVCLQEVWSEKDYLYLKENLKNV 59
           INL+ L   G+  +S  +  R + I   +  +     IV LQE ++++DY  ++ + + +
Sbjct: 31  INLLTLNCWGLRYISTQRNARLDEIGRRIAHAVPTPQIVALQECFTQEDYEAIRHHTRQI 90

Query: 60  LPYSYYFYSGVLGSGLCVFSKWVIQDV 86
           LPY  +++SG  G GL + S W I+++
Sbjct: 91  LPYGKFYHSGAFGGGLAILSHWPIEEI 117


>UniRef50_Q5TEC8 Cluster: Sphingomyelin phosphodiesterase 2, neutral
           membrane; n=2; Homo/Pan/Gorilla group|Rep: Sphingomyelin
           phosphodiesterase 2, neutral membrane - Homo sapiens
           (Human)
          Length = 203

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 5/122 (4%)

Query: 158 TSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNS 217
           TS  ADV +L GDLN  P DL   ++ +   L D Y    E T        G +    N 
Sbjct: 62  TSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAY---LE-TRDFKGSEEGNTMVPKNC 117

Query: 218 YSDPKQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELH 277
           Y   +++K +P G RID++L+     +     +F        P +    SDH A+   L 
Sbjct: 118 YVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSF-ETTTGFDPHRGTPLSDHEALMATLF 176

Query: 278 LK 279
           ++
Sbjct: 177 VR 178


>UniRef50_A0DMK4 Cluster: Chromosome undetermined scaffold_56, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_56,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 352

 Score = 42.3 bits (95), Expect = 0.022
 Identities = 54/182 (29%), Positives = 83/182 (45%), Gaps = 30/182 (16%)

Query: 13  PVVSKN----KKERYEAISTYLLKSEHNIVCLQEVW----SEKDYLYLKE-----NLKNV 59
           PVV+ N    K ER E I   L+  +  IVCLQEV+    S K  L  K        + V
Sbjct: 33  PVVNNNGDDYKNERCELIIKELMNFD--IVCLQEVFGFLNSRKSILKHKAFKLGFTYQAV 90

Query: 60  LPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG 119
            P   +F S ++  GL   S++ I    F ++P  G +      D    KGV   +I   
Sbjct: 91  SPSPSFFSSQMVDGGLVTLSRYPILSHEFKEFPY-GIL-----SDNLSNKGVLYTKILVN 144

Query: 120 ERLINVYCTHLHAEY--HEDDM--YLAHRVLQAYSTAEFVKLT-----SSPADVSILAGD 170
            ++++++ THL A Y   E ++   ++ R+ Q Y   +FV  T     +   D+ +L GD
Sbjct: 145 GQMLHLFNTHLQASYVGKESNVRATVSTRIDQLYCFKKFVHSTLEQQQAQENDLILLVGD 204

Query: 171 LN 172
            N
Sbjct: 205 YN 206


>UniRef50_UPI0000F21D16 Cluster: PREDICTED: similar to
           Mg2+-dependent neutral sphingomyelinase, partial; n=1;
           Danio rerio|Rep: PREDICTED: similar to Mg2+-dependent
           neutral sphingomyelinase, partial - Danio rerio
          Length = 145

 Score = 41.9 bits (94), Expect = 0.029
 Identities = 18/34 (52%), Positives = 24/34 (70%)

Query: 69  GVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHH 102
           GV+GSGL VFSK  IQD   +Q+ LNGY + + +
Sbjct: 1   GVIGSGLAVFSKHRIQDALLYQYSLNGYPYMVSY 34


>UniRef50_Q9NY59 Cluster: Sphingomyelin phosphodiesterase 3; n=22;
           Euteleostomi|Rep: Sphingomyelin phosphodiesterase 3 -
           Homo sapiens (Human)
          Length = 655

 Score = 41.1 bits (92), Expect = 0.051
 Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 22/141 (15%)

Query: 36  NIVCLQEVWSEKDYLYLKENLKNVLPYSYY---FYS-------GVLGSGLCVFSKWVIQD 85
           + +CLQEV+ ++    LKE L     Y  Y    Y          L SGL   S++ I D
Sbjct: 358 DFLCLQEVFDKRAATKLKEQLHGYFEYILYDVGVYGCQGCCSFKCLNSGLLFASRYPIMD 417

Query: 86  VFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFG-----ERLIN-VYCTHLHAEYHEDDM 139
           V +H +P     +K  + D    KG    +++ G     +R++  + CTHLHA   +  +
Sbjct: 418 VAYHCYP-----NKC-NDDALASKGALFLKVQVGSTPQDQRIVGYIACTHLHAPQEDSAI 471

Query: 140 YLAHRVLQAYSTAEFVKLTSS 160
                 L     A+F K TSS
Sbjct: 472 RCGQLDLLQDWLADFRKSTSS 492


>UniRef50_Q2SCA2 Cluster: Endonuclease/exonuclease/phophatase family
           protein; n=2; Oceanospirillales|Rep:
           Endonuclease/exonuclease/phophatase family protein -
           Hahella chejuensis (strain KCTC 2396)
          Length = 445

 Score = 40.7 bits (91), Expect = 0.067
 Identities = 49/175 (28%), Positives = 75/175 (42%), Gaps = 20/175 (11%)

Query: 4   NLMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLPY- 62
           N   LL G+  +SKN   R   ++  +    ++ V  QEV+        + +L+   PY 
Sbjct: 182 NAWALLPGL--MSKNTSNRLATMAEAV--KGYDAVVFQEVFDPILTARFRSDLQAEYPYL 237

Query: 63  -SYYFYSG-VLGSGLCVFSKWVI--QDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKF 118
               F  G +L  G  + S+W I  QD   ++   N           F  KG    +I  
Sbjct: 238 TEIPFKLGRLLTGGSFIASRWPILAQDAMVYEGCRND--------GCFASKGANYAKIDK 289

Query: 119 GERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVS-ILAGDLN 172
           G ++ +++  H HA   E+D+ L    LQ Y    FV    + AD   I+AGDLN
Sbjct: 290 GGQIYHLFGAHTHAYTGEEDVALRRWHLQQYKA--FVDSKGAAADEPVIIAGDLN 342


>UniRef50_P17627 Cluster: Sphingomyelinase C precursor; n=5;
           Leptospira|Rep: Sphingomyelinase C precursor -
           Leptospira interrogans
          Length = 556

 Score = 40.3 bits (90), Expect = 0.089
 Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 10/128 (7%)

Query: 74  GLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVYCTHLHAE 133
           G+ + SKW I++   H +   G        D F  KG    RI    R  ++  TH+ A+
Sbjct: 179 GVVIVSKWPIEEKIQHVFKEKGC-----GADVFSNKGFAYVRIDKNGRKFHIIGTHVQAQ 233

Query: 134 YHE-DDMYLAHRVLQAYSTAEFVKLTSSPA-DVSILAGDLNTAPGDLSYKIISQLPSLLD 191
                ++ +  RV Q     +F+     P  ++ ++AGDLN   G   Y    Q+  +L+
Sbjct: 234 DSGCANLGVVSRVNQFNEIRDFIDSKKIPKNEMVLIAGDLNVIKGSREY---HQMLCILN 290

Query: 192 PYNMKFEG 199
             N K+ G
Sbjct: 291 VNNPKYVG 298


>UniRef50_A3Y6R9 Cluster: Putative uncharacterized protein; n=1;
           Marinomonas sp. MED121|Rep: Putative uncharacterized
           protein - Marinomonas sp. MED121
          Length = 349

 Score = 38.3 bits (85), Expect = 0.36
 Identities = 53/201 (26%), Positives = 85/201 (42%), Gaps = 23/201 (11%)

Query: 5   LMLLLRGIP-VVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKEN---LKNVL 60
           L+  + G P  +  N K   + +   L    +N+V +QE++SE  +  +K+     +   
Sbjct: 69  LVYNIDGFPECIGGNSKSDLKELLKRLESENYNLVLMQEMFSESKHDLVKDEDRLSQQAY 128

Query: 61  PYSYYFYSGVL---GSGLCVFSKWVIQ----DVFFHQWPLNGYI-HKIHHGDWFGG---- 108
           PY    + G +   G GL   S +  Q    D   +    N +  +   HG+ F      
Sbjct: 129 PYRSKHWRGGMTSYGDGLMRLSDFPFQMNSRDNDDYSLTSNEFEEYSACHGNLFDNSPDC 188

Query: 109 ---KGVGLCRIKFGERL-INVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADV 164
              KG  +   +  E   ++VY TH++A   EDD Y A R  Q    A+F+   SS A V
Sbjct: 189 WTEKGFSVAVHEITEDFSVHVYNTHMNAGRDEDD-YNARR-KQFLQLADFINSYSSNATV 246

Query: 165 SILAGDLNTAPGDLSYKIISQ 185
            I+ GD N    D  + +  Q
Sbjct: 247 -IIGGDFNNKWSDYPHAVEQQ 266


>UniRef50_Q93HR5 Cluster: Sphingomyelinase; n=2; cellular
           organisms|Rep: Sphingomyelinase - Pseudomonas sp. TK4
          Length = 516

 Score = 36.7 bits (81), Expect = 1.1
 Identities = 52/232 (22%), Positives = 91/232 (39%), Gaps = 22/232 (9%)

Query: 90  QWPLNGYIHKIHH----GDWFGGKGVGLCRIKFGERLINVYCTHLH-AEYHEDDMYLAHR 144
           +WP+   +  ++H     D    KG    ++  GER  +V  TH   A+    D   A R
Sbjct: 128 RWPIARRVQYLYHDACGADRLANKGFVYVKVLRGERPFHVIATHTQAADSACPDGGRAVR 187

Query: 145 VLQAYSTAEFVKLTSSPA-DVSILAGDLNTAPGDLSY-KIISQLPSLLDPYNMKFEGTNP 202
             Q      F+   + PA +V  + GDLN   G   Y  +++QL  L +P +  + G + 
Sbjct: 188 ESQFREMRAFIDRENIPANEVLFIGGDLNVIRGSDEYPHMLAQL-DLREPDS--YAGASA 244

Query: 203 LIAKASGTSDNLNNSYSD--PKQVKAYPEGKRIDHILFHTNHS----WEARVVNFGNP-- 254
                          Y D  P +  + P  + +D+IL    H     W  + ++  +P  
Sbjct: 245 TFDTRRNGVTGYQYPYKDNGPGKAPSNPP-EYLDYILVSNRHGQVSYWHNQALDIPSPRW 303

Query: 255 -LPDRVPEQQF-SYSDHNAVSLELHLKPCEQKLNQRQESVDSAFQETITQAI 304
              D V    +  YSDH  V+   +  P      Q  +  D+ +   + +++
Sbjct: 304 SASDGVNTWYYQDYSDHYPVAAFTYADPLRTP-QQAYKPTDNRYARVVLRSL 354


>UniRef50_A2QPH4 Cluster: Transposase Tan1-Aspergillus niger; n=3;
           Aspergillus|Rep: Transposase Tan1-Aspergillus niger -
           Aspergillus niger
          Length = 555

 Score = 36.3 bits (80), Expect = 1.4
 Identities = 21/60 (35%), Positives = 26/60 (43%)

Query: 254 PLPDRVPEQQFSYSDHNAVSLELHLKPCEQKLNQRQESVDSAFQETITQAIKVCRDATTN 313
           P PD         + HN   L  H K  E+ L +RQ S  S    T+ Q +K C  A TN
Sbjct: 402 PTPDSQSSGSVLQTPHNIKHLLKHQKSVERLLRKRQASPTSPTNSTLRQLLKGCELAITN 461


>UniRef50_Q5KM82 Cluster: Trehalose-phosphatase, putative; n=2;
           Filobasidiella neoformans|Rep: Trehalose-phosphatase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 989

 Score = 35.9 bits (79), Expect = 1.9
 Identities = 34/140 (24%), Positives = 60/140 (42%), Gaps = 12/140 (8%)

Query: 120 ERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGDLNTAPGDLS 179
           ER+     +H++  Y   D    H   QA    E+  L S  AD++++   L       S
Sbjct: 531 ERMTAELVSHINGTYGSLDFTPVHHYHQALEKDEYFGLLSC-ADLALITS-LRDGMNTTS 588

Query: 180 YK-IISQLPSLLDPYNM-KFEGTNPLIAKAS--------GTSDNLNNSYSDPKQVKAYPE 229
            + I+ Q  +   P  + +F GT P  A A         G +  +N   +  ++ KA   
Sbjct: 589 MEFILCQDKTSKSPLVLSEFMGTAPSFASALQINPHDLLGVAQAINKGLTMREEEKAERH 648

Query: 230 GKRIDHILFHTNHSWEARVV 249
              ++ +L HT+H+W A ++
Sbjct: 649 ANLLEGVLAHTSHTWAATIL 668


>UniRef50_A1A5I2 Cluster: Zgc:154063; n=2; Danio rerio|Rep:
           Zgc:154063 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 969

 Score = 35.5 bits (78), Expect = 2.5
 Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 23/136 (16%)

Query: 96  YIHKIHHGDWFGGKGVGLCRIKFGERLIN------VYCTHLHAEYHEDDMYLAHRVLQAY 149
           YI KIH+   F  K +   R    + L+N      + C H H+ +HE +  +AH  L A+
Sbjct: 434 YIMKIHN---FTSKCLYCNRYLPSDSLLNHMLVHGLSCPHCHSTFHEVEKIVAHNRL-AH 489

Query: 150 STAEFVKLTSSPADVSILAGDLNTAPGDLSYKIISQLPSLLDPYNMKFEGTNPLIAKASG 209
              +  + T SP     L  DL    G+L       +  L+  YNMK     P  A A+ 
Sbjct: 490 PNEQGDQPTGSP-----LTFDLTLQQGNL-----KNVQLLVTTYNMK---ETPEAAAAAA 536

Query: 210 TSDNLNNSYSDPKQVK 225
            ++ L+ + + PK VK
Sbjct: 537 AANQLSQNSAMPKPVK 552


>UniRef50_A0DEC1 Cluster: Chromosome undetermined scaffold_48, whole
           genome shotgun sequence; n=4; Eukaryota|Rep: Chromosome
           undetermined scaffold_48, whole genome shotgun sequence
           - Paramecium tetraurelia
          Length = 1056

 Score = 35.5 bits (78), Expect = 2.5
 Identities = 57/251 (22%), Positives = 95/251 (37%), Gaps = 18/251 (7%)

Query: 48  DYLYLKENLKNVLPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFG 107
           D L+ + NL  + PY+    S ++G  + VF K            ++  + K   G   G
Sbjct: 575 DQLF-QSNLSKIEPYTKIGESDLVGLYMAVFVK---TSQISRVTQIDTDVVKTGLGGTLG 630

Query: 108 GKGVGLCRIKFGERLINVYCTHLHAEYHEDDMYLA--HRVLQAYSTAEFVKLTSSPADVS 165
            KG    + KF +  +   C HL +   +    L+    + Q        K T +  D S
Sbjct: 631 NKGGVSVKFKFDDSQLGFTCCHLTSGNKQCQQRLSDVDEIHQRAFQNSKSKTTLNDLDYS 690

Query: 166 ILAGDLNTAPGDLSY-KIISQLPSLLDPYNMKFEGTNPLIAKA-SGTSDNLNNSYSDPKQ 223
              GD+N    DL Y ++I Q+       +      N     A     D L  + +  + 
Sbjct: 691 FFFGDMNFRI-DLPYQEVIEQIRHYQQLISQDQNNPNAKAKLAYLLNQDQLGKNKNRNQY 749

Query: 224 VKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHNAVSLELHLKPCEQ 283
           ++ Y EG     I F   + ++     +      R P    S+ D   VS +  L  C+Q
Sbjct: 750 LQNYQEGS----IFFLPTYKYDKNCQVYDTSKKQRTP----SWCDRILVSCKEEL-ICQQ 800

Query: 284 KLNQRQESVDS 294
           +  +R E +DS
Sbjct: 801 RFYKRNECLDS 811


>UniRef50_Q8CVD9 Cluster: Sphingomyelinase C; n=5; Leptospira
           interrogans|Rep: Sphingomyelinase C - Leptospira
           interrogans
          Length = 558

 Score = 35.1 bits (77), Expect = 3.3
 Identities = 34/132 (25%), Positives = 58/132 (43%), Gaps = 12/132 (9%)

Query: 66  FYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHH--GDWFGGKGVGLCRIKFGERLI 123
           F   +   G+ + SKW IQ+          YI K H    D F  KG    +IK G ++I
Sbjct: 164 FRQQINNGGVVILSKWPIQEKI-------QYIFKNHGCGNDTFYNKGFAYVKIKKGSQII 216

Query: 124 NVYCTHLHAEYHE-DDMYLAHRVLQAYSTAEFV-KLTSSPADVSILAGDLNTAPGDLS-Y 180
           ++  T   +E     D+ +  R+ Q     +F+     S  ++ ++AG LN    + S Y
Sbjct: 217 HIVGTDTQSEDSTCSDLGVNARINQLTEIKKFIDSKRISNKEIVLIAGALNVDKSNQSEY 276

Query: 181 KIISQLPSLLDP 192
           K +  +  + +P
Sbjct: 277 KNMLNILEVNEP 288


>UniRef50_Q5AVC8 Cluster: Ferrochelatase; n=9; Fungi/Metazoa
           group|Rep: Ferrochelatase - Emericella nidulans
           (Aspergillus nidulans)
          Length = 419

 Score = 35.1 bits (77), Expect = 3.3
 Identities = 17/37 (45%), Positives = 21/37 (56%)

Query: 223 QVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRV 259
           Q+K YPE KR   +L  + HS    VVN G+P P  V
Sbjct: 239 QLKTYPEEKRNSVVLLFSAHSLPMSVVNRGDPYPAEV 275


>UniRef50_A7F024 Cluster: Predicted protein; n=1; Sclerotinia
           sclerotiorum 1980|Rep: Predicted protein - Sclerotinia
           sclerotiorum 1980
          Length = 880

 Score = 35.1 bits (77), Expect = 3.3
 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 2/68 (2%)

Query: 200 TNPLIAKA-SGTSDNLNNSYSDPKQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDR 258
           T+P++A+  + T+ +L  +YS+ +Q    P  ++ DH+  H    +E    + GN  PD 
Sbjct: 392 TSPILARELTATNRSLGGNYSESQQGSQSPGAEQSDHVGQHQLRRYETASEHHGN-RPDV 450

Query: 259 VPEQQFSY 266
           V    F Y
Sbjct: 451 VSHPTFGY 458


>UniRef50_P59116 Cluster: Sphingomyelinase C 2 precursor; n=6;
           Leptospira interrogans|Rep: Sphingomyelinase C 2
           precursor - Leptospira interrogans
          Length = 623

 Score = 35.1 bits (77), Expect = 3.3
 Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 9/123 (7%)

Query: 67  YSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKFGERLINVY 126
           YS V G G+ + SKW I++   + +  +G        DWF  KG    +I    +  +V 
Sbjct: 242 YSLVNG-GVVILSKWPIEEKIQYIFNDSGC-----GADWFANKGFVYVKINKEGKKFHVI 295

Query: 127 CTHLHAEYHE-DDMYLAHRVLQAYSTAEFVKLTSSPADVSIL-AGDLNT-APGDLSYKII 183
            TH  ++     ++ + +R  Q      F+   + P D ++L  GDLN     +  Y +I
Sbjct: 296 GTHAQSQDQNCSNLGIPNRANQFDDIRNFIYSKNIPKDETVLIVGDLNVIKESNEYYDMI 355

Query: 184 SQL 186
           S+L
Sbjct: 356 SRL 358


>UniRef50_O51552 Cluster: Rep helicase, single-stranded
           DNA-dependent ATPase; n=3; Borrelia burgdorferi
           group|Rep: Rep helicase, single-stranded DNA-dependent
           ATPase - Borrelia burgdorferi (Lyme disease spirochete)
          Length = 659

 Score = 34.7 bits (76), Expect = 4.4
 Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 1/62 (1%)

Query: 336 VGFWPNFLIYDVLKLLITALCFYNLVMGSLWNQIEMNSLKAGLNALENFIQTRNDTKPED 395
           +G+  NF IYD     I+ L    L  G    ++ +NSL   ++ L+N I T ND K ED
Sbjct: 105 LGYRKNFSIYDDNDR-ISLLKEILLDEGLFNKKVSLNSLSNVISLLKNGILTLNDLKEED 163

Query: 396 IN 397
           IN
Sbjct: 164 IN 165


>UniRef50_Q9N467 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 604

 Score = 34.7 bits (76), Expect = 4.4
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 5/84 (5%)

Query: 121 RLINVYCTHLHAEYHED---DMYLAHRVLQAYST-AEFVKLTSSPAD-VSILAGDLNTAP 175
           R+IN Y T LHAE  E    +M +  RV +  +  +E+ K  +   D +++++ DL  A 
Sbjct: 94  RVINAYGTVLHAEVDEKVKLEMAMERRVYEELAPFSEYEKNVNKLKDKLNLVSTDLEIAQ 153

Query: 176 GDLSYKIISQLPSLLDPYNMKFEG 199
            DL  +        LD   MK+EG
Sbjct: 154 KDLEKENSMTHQESLDAIQMKYEG 177


>UniRef50_Q4UHF9 Cluster: Putative uncharacterized protein; n=2;
           Theileria|Rep: Putative uncharacterized protein -
           Theileria annulata
          Length = 1233

 Score = 34.7 bits (76), Expect = 4.4
 Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 2/74 (2%)

Query: 155 VKLTSSPADVSILAGDLNTAPG--DLSYKIISQLPSLLDPYNMKFEGTNPLIAKASGTSD 212
           ++ T+ P+ V ++  DLN  P   DL    ++ +PS +D  N      + +    SGT  
Sbjct: 344 IQNTTIPSTVDLVTSDLNNIPSTVDLVNNDLNNIPSAVDLVNNDLNIPSAVNLVTSGTMV 403

Query: 213 NLNNSYSDPKQVKA 226
           N  N  +D K+V++
Sbjct: 404 NGMNGMNDVKEVES 417


>UniRef50_A7AR39 Cluster: Endonuclease/exonuclease/phosphatase
           family protein; n=1; Babesia bovis|Rep:
           Endonuclease/exonuclease/phosphatase family protein -
           Babesia bovis
          Length = 319

 Score = 34.7 bits (76), Expect = 4.4
 Identities = 51/212 (24%), Positives = 87/212 (41%), Gaps = 28/212 (13%)

Query: 26  ISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVL--------PYSYYFYSGVLGSGLCV 77
           IS+   K + +I+ LQEV+S   Y  +K+ L+ +         P S       L + L  
Sbjct: 38  ISSLFQKYDVDIMVLQEVFSYSLYNKIKDALRGIAEDTGIISRPVSNSVLMSCLDTLLST 97

Query: 78  FSKWVIQDVFFHQWPLNGYIHKI-----HHGDWFGGKGVGLCRIKFGERLINVYCTHLHA 132
           FS      V F + P+  Y  ++      + + + GKG    RI     L++V  THL +
Sbjct: 98  FSFITSGIVIFSRHPIV-YKERLLFSNGFNAERYAGKGAVAARISVNGNLLDVIGTHLQS 156

Query: 133 EYHEDDMYLAHRVLQAYSTAEFVKLT------------SSPADVSILAGDLNTAPGDLSY 180
           +  ED   + ++  Q    AE++ +             S P    +LAGDLN +    + 
Sbjct: 157 DEGEDAQEIRNK--QLIELAEWIGINPLEDERAIAERDSLPYVPMVLAGDLNCSLDSETE 214

Query: 181 KIISQLPSLLDPYNMKFEGTNPLIAKASGTSD 212
           +    + +L D     F    P    ++ T+D
Sbjct: 215 RFSDVVAALNDKLEDTFGYNQPEPTYSTLTND 246


>UniRef50_P22657 Cluster: RNA replication protein (152 kDa protein)
           (ORF 1 protein) [Includes: RNA-directed RNA polymerase
           (EC 2.7.7.48); Helicase (EC 3.6.1.-)]; n=20;
           Carlavirus|Rep: RNA replication protein (152 kDa
           protein) (ORF 1 protein) [Includes: RNA-directed RNA
           polymerase (EC 2.7.7.48); Helicase (EC 3.6.1.-)] -
           Potato virus S (strain Peruvian)
          Length = 353

 Score = 34.7 bits (76), Expect = 4.4
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 6/59 (10%)

Query: 32  KSEHNIVCLQE--VWSEKDYL-YLKENLKNVLPYSYYFYSGVLGSGLCVFSKWVIQDVF 87
           K+   IVC Q   +     Y+ Y+++ L  VLP ++Y +S   G GL   +KWVI+  F
Sbjct: 80  KAAQTIVCFQHSVLCRFAPYMRYIEKKLNEVLPATFYIHS---GKGLEELNKWVIESKF 135


>UniRef50_UPI00006CF82F Cluster:
           Endonuclease/Exonuclease/phosphatase family protein;
           n=1; Tetrahymena thermophila SB210|Rep:
           Endonuclease/Exonuclease/phosphatase family protein -
           Tetrahymena thermophila SB210
          Length = 480

 Score = 34.3 bits (75), Expect = 5.8
 Identities = 48/202 (23%), Positives = 90/202 (44%), Gaps = 29/202 (14%)

Query: 2   IINLMLLLRGIPVVSKNKKERYEAISTYLLK---SEHNIVCLQEVW---SEKDYLYLKEN 55
           ++   + LR  P+  KN K+ Y+   T L     S+ +IVCLQE++   +++ +  +   
Sbjct: 79  VLTYNIFLRPPPI--KNNKDDYKNERTKLFLNSISDFDIVCLQELFGFLNQRKHKIIFNA 136

Query: 56  LKN------VLPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGK 109
           +K         P   +F S ++  GL   S++ I +  +  +   G +      D    K
Sbjct: 137 MKQGFFYHATSPSPSFFSSYLVDGGLVTISRFPIIEKSYRPFKY-GVL-----SDNLSQK 190

Query: 110 GVGLCRIKFGERLINVYCTHLHAEY--HEDDM--YLAHRVLQAYSTAEFV-----KLTSS 160
           GV   +I+  +  I+++ THL A Y   E+++   +  RV Q     +F+     K    
Sbjct: 191 GVLYTKIQANDSYIHLFNTHLQASYVGAENNVKATVITRVDQLILIKDFIKEQVKKHREK 250

Query: 161 PADVSILAGDLNTAPGDLSYKI 182
            +D+ ++ GD N      +Y I
Sbjct: 251 ESDIIMICGDFNVNARPQTYPI 272


>UniRef50_A6F7A0 Cluster: Putative phospholipase C; n=1; Moritella
           sp. PE36|Rep: Putative phospholipase C - Moritella sp.
           PE36
          Length = 428

 Score = 34.3 bits (75), Expect = 5.8
 Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 7/74 (9%)

Query: 109 KGVGLCRIKFGERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVS-IL 167
           +GV   RI     + +V+ TH  +   +DD     R+ Q     EF++  + PAD + IL
Sbjct: 269 RGVIYTRINKQGYIYHVFATHTQSS--DDDTNRTARLAQLEEMGEFIREQNIPADEAVIL 326

Query: 168 AGDLNT----APGD 177
           AGD N      PGD
Sbjct: 327 AGDFNVNKIGLPGD 340


>UniRef50_A5ID83 Cluster: Putative uncharacterized protein; n=4;
           Legionella pneumophila|Rep: Putative uncharacterized
           protein - Legionella pneumophila (strain Corby)
          Length = 882

 Score = 34.3 bits (75), Expect = 5.8
 Identities = 20/74 (27%), Positives = 33/74 (44%)

Query: 109 KGVGLCRIKFGERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILA 168
           K   L R+K  +R+I  YC H+   +H     +  ++ +  +  E V+LT    DV IL 
Sbjct: 447 KYASLVRLKELKRIITQYCDHISWLHHNRTQAIKKQLQEELAKDERVRLTEELNDVEILE 506

Query: 169 GDLNTAPGDLSYKI 182
            D       +  +I
Sbjct: 507 KDAEQIKSQILIRI 520


>UniRef50_A4M652 Cluster: DegV family protein; n=1; Petrotoga
           mobilis SJ95|Rep: DegV family protein - Petrotoga
           mobilis SJ95
          Length = 292

 Score = 34.3 bits (75), Expect = 5.8
 Identities = 19/73 (26%), Positives = 35/73 (47%)

Query: 1   FIINLMLLLRGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVL 60
           F+  ++  ++ +    K+ +E    IS  +   +  I+C +    ++D  Y+ E LK  L
Sbjct: 200 FVNGVVKPIKAVRSRRKSLEEMVNIISDRIKDPKKAIICTRNAICKEDEEYMIEKLKEKL 259

Query: 61  PYSYYFYSGVLGS 73
            Y    YSG LG+
Sbjct: 260 NYEGEIYSGTLGA 272


>UniRef50_Q332A8 Cluster: Conserved hypothetical phage-related
           protein; n=1; Clostridium phage c-st|Rep: Conserved
           hypothetical phage-related protein - Clostridium
           botulinum C bacteriophage
          Length = 451

 Score = 34.3 bits (75), Expect = 5.8
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 2/71 (2%)

Query: 31  LKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYFYSGVLGSGLCVFSKWVIQDVFFHQ 90
           L S+++ V LQ++       Y+ E  KN LP+  +  + V    L  F K  +QDVF  +
Sbjct: 296 LLSKNDFVKLQDIEKNAQKNYVGEEAKNALPFYVHTKTIVFELPLNKF-KQGVQDVFV-K 353

Query: 91  WPLNGYIHKIH 101
           +P+NG I  I+
Sbjct: 354 FPMNGQITNIN 364


>UniRef50_Q7QTT1 Cluster: GLP_191_17261_17716; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_191_17261_17716 - Giardia lamblia
           ATCC 50803
          Length = 151

 Score = 34.3 bits (75), Expect = 5.8
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 7/77 (9%)

Query: 18  NKKERYEAISTYL--LKSEHNIVCLQEVWSEKDYLYLKENLKNVLPYSYYF-YSGVLGSG 74
           N K+  +A+S  L   KSE  +      W EK   ++   L+    YS+Y   S  + SG
Sbjct: 70  NLKKFMKAMSKNLKKTKSEEEVAA----WQEKVNAWVTGLLEKFDDYSFYLGASNDVESG 125

Query: 75  LCVFSKWVIQDVFFHQW 91
           + VF KW   D +F+ W
Sbjct: 126 MVVFCKWDGADPYFYYW 142


>UniRef50_Q8YVZ6 Cluster: All1820 protein; n=2; Nostocaceae|Rep:
           All1820 protein - Anabaena sp. (strain PCC 7120)
          Length = 1009

 Score = 33.9 bits (74), Expect = 7.7
 Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 2/91 (2%)

Query: 116 IKFGERLINVYCTHLHAEYHEDDMYLAHRV-LQAYSTAEFVKLTSSPADVSILAG-DLNT 173
           I FG+ L N+  T  +A     +  +A  V L+   TAEF K T +PA V+++     N+
Sbjct: 592 IAFGQELTNLRQTPANARTAIQEKRIAELVKLEQTITAEFNKFTKTPAVVALVQQLSANS 651

Query: 174 APGDLSYKIISQLPSLLDPYNMKFEGTNPLI 204
              +LS + ++ L   L   N K     PL+
Sbjct: 652 GQENLSLRQLNSLRDNLRQLNKKAVLLYPLV 682


>UniRef50_A6CBS1 Cluster: Probable aggregation factor core protein
           MAFp3, isoform C; n=1; Planctomyces maris DSM 8797|Rep:
           Probable aggregation factor core protein MAFp3, isoform
           C - Planctomyces maris DSM 8797
          Length = 1133

 Score = 33.9 bits (74), Expect = 7.7
 Identities = 27/109 (24%), Positives = 41/109 (37%), Gaps = 3/109 (2%)

Query: 162 ADVSILAGDLNTAPGDLSYKIISQLPSLLDPYNMKFEGTNPLIAKASGTSDNLNNSYSDP 221
           AD  +L   +  +PG      +   P+ + PYN+ FE TN  +     T   +N   S  
Sbjct: 807 ADSPVLFARVRFSPGSEDQVSLETEPNSIGPYNLNFEITNSHVELGGNTPVTVNVDLSPG 866

Query: 222 KQVKAYPEGKRIDHILFHTNHSWEARVVNFGNPLPDRVPEQQFSYSDHN 270
             + A P     D I+   N+      V   N +P         +SD N
Sbjct: 867 ASIYANPFDLNDDDII---NYRDLILFVGLYNTVPSESDSSFAWFSDFN 912


>UniRef50_O96266 Cluster: Putative uncharacterized protein PFB0870w;
           n=1; Plasmodium falciparum 3D7|Rep: Putative
           uncharacterized protein PFB0870w - Plasmodium falciparum
           (isolate 3D7)
          Length = 2380

 Score = 33.9 bits (74), Expect = 7.7
 Identities = 13/28 (46%), Positives = 19/28 (67%)

Query: 40  LQEVWSEKDYLYLKENLKNVLPYSYYFY 67
           +  +W EKDYL+L ENLK++L    + Y
Sbjct: 880 INNLWIEKDYLFLIENLKDILERKIFDY 907


>UniRef50_A6R9W9 Cluster: Predicted protein; n=1; Ajellomyces
           capsulatus NAm1|Rep: Predicted protein - Ajellomyces
           capsulatus NAm1
          Length = 330

 Score = 33.9 bits (74), Expect = 7.7
 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 1/91 (1%)

Query: 111 VGLCRIKFGERLINVYCTHLHAEYHEDDMYLAHRVLQAYSTAEFVKLTSSPADVSILAGD 170
           +G+ R K    +  V  THL  +  E  ++ +  +L+     +  +         IL GD
Sbjct: 172 IGVFRNKRTRAMALVMNTHLDHQVSEARLHGSELILKLIGDYKNKRQYKCKLTGVILTGD 231

Query: 171 LNTAPGDLSYKIISQLPSLLDPYNMKFEGTN 201
            N+  G  +YK+I++   L+DP   KF   N
Sbjct: 232 FNSEEGQEAYKVITESKVLVDPVK-KFGDKN 261


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.320    0.137    0.421 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 464,496,757
Number of Sequences: 1657284
Number of extensions: 20444116
Number of successful extensions: 48261
Number of sequences better than 10.0: 58
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 48162
Number of HSP's gapped (non-prelim): 70
length of query: 404
length of database: 575,637,011
effective HSP length: 102
effective length of query: 302
effective length of database: 406,594,043
effective search space: 122791400986
effective search space used: 122791400986
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 74 (33.9 bits)

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