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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001137-TA|BGIBMGA001137-PA|IPR000398|Thymidylate
synthase
         (253 letters)

Database: fruitfly 
           52,641 sequences; 24,830,863 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY089595-1|AAL90333.1|  321|Drosophila melanogaster RE18955p pro...   384   e-107
AF073994-3|AAC27622.1|  321|Drosophila melanogaster thymidylate ...   384   e-107
AE014134-521|AAF51176.1|  321|Drosophila melanogaster CG3181-PA ...   384   e-107
AF233659-1|AAF42939.1| 1530|Drosophila melanogaster RECQ4 protein.     31   2.0  
AE014296-1383|AAF50477.1| 1579|Drosophila melanogaster CG7487-PA...    31   2.0  
AE014134-756|AAN10358.4| 23015|Drosophila melanogaster CG33196-P...    29   6.2  
AY061340-1|AAL28888.1|  608|Drosophila melanogaster LD27045p pro...    29   8.2  
AE014296-2271|AAN11835.1|  604|Drosophila melanogaster CG10724-P...    29   8.2  
AE014296-2270|AAF49822.1|  608|Drosophila melanogaster CG10724-P...    29   8.2  

>AY089595-1|AAL90333.1|  321|Drosophila melanogaster RE18955p
           protein.
          Length = 321

 Score =  384 bits (945), Expect = e-107
 Identities = 169/247 (68%), Positives = 203/247 (82%), Gaps = 2/247 (0%)

Query: 9   NTLPLLTPKRVFTRGVIEELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREE 68
           N+ PLLT KRVF R V EELLW ++G TD+K L AK VHIWD N SR FLD +GFT R  
Sbjct: 75  NSFPLLTTKRVFFRAVAEELLWFVAGKTDAKLLQAKNVHIWDGNSSREFLDKMGFTGRAV 134

Query: 69  GDLGPVYGFQWRHSGAKYIDCQTDYTGQGIDQLQSVIDSIKNNPADRRMLICAWNSSDLK 128
           GDLGPVYGFQWRH GA+Y  C  DY+G+GIDQL+ VID+I+NNP+DRR+++ AWN  D+ 
Sbjct: 135 GDLGPVYGFQWRHFGAQYGTCDDDYSGKGIDQLRQVIDTIRNNPSDRRIIMSAWNPLDIP 194

Query: 129 KMALPPCHCLAQFYVAD--GKLSCLLYQRSADMGLGVPFNIASYSLLTHMIAHVTGYQAG 186
           KMALPPCHCLAQFYV++  G+LSC LYQRSADMGLGVPFNIASY+LLTHMIAHVTG + G
Sbjct: 195 KMALPPCHCLAQFYVSEKRGELSCQLYQRSADMGLGVPFNIASYALLTHMIAHVTGLKPG 254

Query: 187 EFIHTTGDTHVYLNHIEPLKIQLQREPKQFPTLEFARKIESIDDFKYEDFIIKDYKPHPK 246
           +F+HT GDTHVYLNH+EPLK QL+R P+ FP L   R+++ I+DF++EDF I DY PHPK
Sbjct: 255 DFVHTMGDTHVYLNHVEPLKEQLERTPRPFPKLIIKRQVQDIEDFRFEDFQIVDYNPHPK 314

Query: 247 IEMEMAV 253
           I+M+MAV
Sbjct: 315 IQMDMAV 321


>AF073994-3|AAC27622.1|  321|Drosophila melanogaster thymidylate
           synthase protein.
          Length = 321

 Score =  384 bits (945), Expect = e-107
 Identities = 169/247 (68%), Positives = 203/247 (82%), Gaps = 2/247 (0%)

Query: 9   NTLPLLTPKRVFTRGVIEELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREE 68
           N+ PLLT KRVF R V EELLW ++G TD+K L AK VHIWD N SR FLD +GFT R  
Sbjct: 75  NSFPLLTTKRVFFRAVAEELLWFVAGKTDAKLLQAKNVHIWDGNSSREFLDKMGFTGRAV 134

Query: 69  GDLGPVYGFQWRHSGAKYIDCQTDYTGQGIDQLQSVIDSIKNNPADRRMLICAWNSSDLK 128
           GDLGPVYGFQWRH GA+Y  C  DY+G+GIDQL+ VID+I+NNP+DRR+++ AWN  D+ 
Sbjct: 135 GDLGPVYGFQWRHFGAQYGTCDDDYSGKGIDQLRQVIDTIRNNPSDRRIIMSAWNPLDMP 194

Query: 129 KMALPPCHCLAQFYVAD--GKLSCLLYQRSADMGLGVPFNIASYSLLTHMIAHVTGYQAG 186
           KMALPPCHCLAQFYV++  G+LSC LYQRSADMGLGVPFNIASY+LLTHMIAHVTG + G
Sbjct: 195 KMALPPCHCLAQFYVSEKRGELSCQLYQRSADMGLGVPFNIASYALLTHMIAHVTGLKPG 254

Query: 187 EFIHTTGDTHVYLNHIEPLKIQLQREPKQFPTLEFARKIESIDDFKYEDFIIKDYKPHPK 246
           +F+HT GDTHVYLNH+EPLK QL+R P+ FP L   R+++ I+DF++EDF I DY PHPK
Sbjct: 255 DFVHTMGDTHVYLNHVEPLKEQLERTPRPFPKLIIKRQVQDIEDFRFEDFQIVDYNPHPK 314

Query: 247 IEMEMAV 253
           I+M+MAV
Sbjct: 315 IQMDMAV 321


>AE014134-521|AAF51176.1|  321|Drosophila melanogaster CG3181-PA
           protein.
          Length = 321

 Score =  384 bits (945), Expect = e-107
 Identities = 169/247 (68%), Positives = 203/247 (82%), Gaps = 2/247 (0%)

Query: 9   NTLPLLTPKRVFTRGVIEELLWMISGSTDSKALAAKGVHIWDANGSRNFLDNLGFTDREE 68
           N+ PLLT KRVF R V EELLW ++G TD+K L AK VHIWD N SR FLD +GFT R  
Sbjct: 75  NSFPLLTTKRVFFRAVAEELLWFVAGKTDAKLLQAKNVHIWDGNSSREFLDKMGFTGRAV 134

Query: 69  GDLGPVYGFQWRHSGAKYIDCQTDYTGQGIDQLQSVIDSIKNNPADRRMLICAWNSSDLK 128
           GDLGPVYGFQWRH GA+Y  C  DY+G+GIDQL+ VID+I+NNP+DRR+++ AWN  D+ 
Sbjct: 135 GDLGPVYGFQWRHFGAQYGTCDDDYSGKGIDQLRQVIDTIRNNPSDRRIIMSAWNPLDIP 194

Query: 129 KMALPPCHCLAQFYVAD--GKLSCLLYQRSADMGLGVPFNIASYSLLTHMIAHVTGYQAG 186
           KMALPPCHCLAQFYV++  G+LSC LYQRSADMGLGVPFNIASY+LLTHMIAHVTG + G
Sbjct: 195 KMALPPCHCLAQFYVSEKRGELSCQLYQRSADMGLGVPFNIASYALLTHMIAHVTGLKPG 254

Query: 187 EFIHTTGDTHVYLNHIEPLKIQLQREPKQFPTLEFARKIESIDDFKYEDFIIKDYKPHPK 246
           +F+HT GDTHVYLNH+EPLK QL+R P+ FP L   R+++ I+DF++EDF I DY PHPK
Sbjct: 255 DFVHTMGDTHVYLNHVEPLKEQLERTPRPFPKLIIKRQVQDIEDFRFEDFQIVDYNPHPK 314

Query: 247 IEMEMAV 253
           I+M+MAV
Sbjct: 315 IQMDMAV 321


>AF233659-1|AAF42939.1| 1530|Drosophila melanogaster RECQ4 protein.
          Length = 1530

 Score = 30.7 bits (66), Expect = 2.0
 Identities = 16/48 (33%), Positives = 25/48 (52%)

Query: 180 VTGYQAGEFIHTTGDTHVYLNHIEPLKIQLQREPKQFPTLEFARKIES 227
           +T +Q G   H      V  + + PL  QL+ +P  FPTL  A+++ S
Sbjct: 626 LTCFQCGGVGHFAQQCKVKGDSLLPLSAQLEEDPSPFPTLAEAQEMAS 673


>AE014296-1383|AAF50477.1| 1579|Drosophila melanogaster CG7487-PA
           protein.
          Length = 1579

 Score = 30.7 bits (66), Expect = 2.0
 Identities = 16/48 (33%), Positives = 25/48 (52%)

Query: 180 VTGYQAGEFIHTTGDTHVYLNHIEPLKIQLQREPKQFPTLEFARKIES 227
           +T +Q G   H      V  + + PL  QL+ +P  FPTL  A+++ S
Sbjct: 675 LTCFQCGGVGHFAQQCKVKGDSLLPLSAQLEEDPSPFPTLAEAQEMAS 722


>AE014134-756|AAN10358.4| 23015|Drosophila melanogaster CG33196-PB
             protein.
          Length = 23015

 Score = 29.1 bits (62), Expect = 6.2
 Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 2/59 (3%)

Query: 86    YIDCQTDYTGQGIDQLQSVIDSIKN-NPADR-RMLICAWNSSDLKKMALPPCHCLAQFY 142
             +  C+  YTG  I Q   +I+  ++  P D  +   C  NS   +    P C CL+ F+
Sbjct: 15909 FCSCRPGYTGNPIVQCHMIIEPQRDITPKDPCQPSPCGPNSECRRVGETPSCSCLSNFF 15967


>AY061340-1|AAL28888.1|  608|Drosophila melanogaster LD27045p
           protein.
          Length = 608

 Score = 28.7 bits (61), Expect = 8.2
 Identities = 13/63 (20%), Positives = 27/63 (42%), Gaps = 2/63 (3%)

Query: 72  GPVYGFQWRHSGAKYIDCQTDYTGQ--GIDQLQSVIDSIKNNPADRRMLICAWNSSDLKK 129
           G VY   W+    + + C  D T +   ++  + V + +     D + + C W   +L  
Sbjct: 240 GGVYALAWKPDSTQLLTCSGDKTCRLWTVESRELVSEFVMGTTVDDQQVSCLWQGDNLIT 299

Query: 130 MAL 132
           ++L
Sbjct: 300 VSL 302


>AE014296-2271|AAN11835.1|  604|Drosophila melanogaster CG10724-PB,
           isoform B protein.
          Length = 604

 Score = 28.7 bits (61), Expect = 8.2
 Identities = 13/63 (20%), Positives = 27/63 (42%), Gaps = 2/63 (3%)

Query: 72  GPVYGFQWRHSGAKYIDCQTDYTGQ--GIDQLQSVIDSIKNNPADRRMLICAWNSSDLKK 129
           G VY   W+    + + C  D T +   ++  + V + +     D + + C W   +L  
Sbjct: 236 GGVYALAWKPDSTQLLTCSGDKTCRLWTVESRELVSEFVMGTTVDDQQVSCLWQGDNLIT 295

Query: 130 MAL 132
           ++L
Sbjct: 296 VSL 298


>AE014296-2270|AAF49822.1|  608|Drosophila melanogaster CG10724-PA,
           isoform A protein.
          Length = 608

 Score = 28.7 bits (61), Expect = 8.2
 Identities = 13/63 (20%), Positives = 27/63 (42%), Gaps = 2/63 (3%)

Query: 72  GPVYGFQWRHSGAKYIDCQTDYTGQ--GIDQLQSVIDSIKNNPADRRMLICAWNSSDLKK 129
           G VY   W+    + + C  D T +   ++  + V + +     D + + C W   +L  
Sbjct: 240 GGVYALAWKPDSTQLLTCSGDKTCRLWTVESRELVSEFVMGTTVDDQQVSCLWQGDNLIT 299

Query: 130 MAL 132
           ++L
Sbjct: 300 VSL 302


  Database: fruitfly
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 24,830,863
  Number of sequences in database:  52,641
  
Lambda     K      H
   0.321    0.138    0.428 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 13,489,755
Number of Sequences: 52641
Number of extensions: 577478
Number of successful extensions: 1186
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1176
Number of HSP's gapped (non-prelim): 13
length of query: 253
length of database: 24,830,863
effective HSP length: 83
effective length of query: 170
effective length of database: 20,461,660
effective search space: 3478482200
effective search space used: 3478482200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 61 (28.7 bits)

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