Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001130-TA|BGIBMGA001130-PA|IPR002524|Cation efflux
protein
(353 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B61F4 Cluster: PREDICTED: similar to GA14626-PA... 438 e-121
UniRef50_Q7K3K5 Cluster: LD22804p; n=7; Endopterygota|Rep: LD228... 427 e-118
UniRef50_UPI0000E49D68 Cluster: PREDICTED: similar to CG17723-PA... 271 2e-71
UniRef50_Q75D95 Cluster: ABR129Cp; n=2; Saccharomycetaceae|Rep: ... 211 2e-53
UniRef50_UPI000049966E Cluster: cation diffusion facilitator fam... 203 6e-51
UniRef50_A1DD01 Cluster: Metal ion resistance protein/transporte... 199 1e-49
UniRef50_A5DPS6 Cluster: Putative uncharacterized protein; n=1; ... 194 3e-48
UniRef50_Q5GR56 Cluster: Zinc transporter 1; n=1; Glomus intrara... 151 4e-35
UniRef50_P20107 Cluster: Zinc/cadmium resistance protein; n=7; S... 148 2e-34
UniRef50_A1D9L0 Cluster: Di-, tri-valent inorganic cation transp... 148 2e-34
UniRef50_Q5KK51 Cluster: Di-, tri-valent inorganic cation transp... 142 2e-32
UniRef50_A7TP59 Cluster: Putative uncharacterized protein; n=1; ... 141 2e-32
UniRef50_Q6P3M0 Cluster: Solute carrier family 30 (Zinc transpor... 137 5e-31
UniRef50_Q54T06 Cluster: Cation efflux family protein; n=1; Dict... 134 2e-30
UniRef50_A5ABY7 Cluster: Function: Zinc-replete cells accumulate... 134 2e-30
UniRef50_Q5BCD5 Cluster: Putative uncharacterized protein; n=1; ... 134 4e-30
UniRef50_A1DI13 Cluster: Zinc/cadmium resistance protein; n=8; P... 134 4e-30
UniRef50_UPI0000DB7A0C Cluster: PREDICTED: similar to CG5130-PA,... 130 4e-29
UniRef50_Q4SCU9 Cluster: Chromosome 14 SCAF14647, whole genome s... 130 5e-29
UniRef50_A2R2G7 Cluster: Remark: the protein is probably respons... 130 7e-29
UniRef50_Q9Y6M5 Cluster: Zinc transporter 1; n=25; Euteleostomi|... 128 2e-28
UniRef50_Q2PIQ1 Cluster: Zn2+ transporter ZNT1 and related Cd2+/... 128 2e-28
UniRef50_UPI0000D55EC2 Cluster: PREDICTED: similar to CG5130-PA,... 124 3e-27
UniRef50_UPI000155D410 Cluster: PREDICTED: similar to Eprs prote... 124 5e-27
UniRef50_A6SSD0 Cluster: Putative uncharacterized protein; n=2; ... 123 6e-27
UniRef50_Q2H0R9 Cluster: Putative uncharacterized protein; n=1; ... 120 6e-26
UniRef50_A7PMH0 Cluster: Chromosome chr14 scaffold_21, whole gen... 119 1e-25
UniRef50_A0S5V1 Cluster: Putative solute carrier family 30; n=1;... 119 1e-25
UniRef50_Q2HFW8 Cluster: Putative uncharacterized protein; n=2; ... 118 2e-25
UniRef50_Q0CAH3 Cluster: Predicted protein; n=1; Aspergillus ter... 118 2e-25
UniRef50_Q9VPE3 Cluster: CG5130-PA, isoform A; n=5; Diptera|Rep:... 118 2e-25
UniRef50_Q5ALP0 Cluster: Potential vacuolar cation transporter; ... 118 2e-25
UniRef50_A4QRA6 Cluster: Putative uncharacterized protein; n=2; ... 118 2e-25
UniRef50_UPI00015A66AB Cluster: solute carrier family 30 (zinc t... 118 3e-25
UniRef50_Q6XR72 Cluster: Solute carrier family 30 member 10; n=1... 118 3e-25
UniRef50_Q6UX54 Cluster: Solute carrier family 30 member 5; n=49... 117 4e-25
UniRef50_A3LTE1 Cluster: Zinc-and cadmium resistance protein; n=... 117 4e-25
UniRef50_O13918 Cluster: Zinc homeostasis factor 1; n=1; Schizos... 112 1e-23
UniRef50_Q6DBM8 Cluster: Metal tolerance protein B; n=1; Arabido... 112 1e-23
UniRef50_Q29M69 Cluster: GA16530-PA; n=2; Endopterygota|Rep: GA1... 112 2e-23
UniRef50_UPI000069F760 Cluster: solute carrier family 30 (zinc t... 111 3e-23
UniRef50_Q8TCH2 Cluster: Zinc transporter-like 2 protein; n=37; ... 111 3e-23
UniRef50_Q95QW4 Cluster: Cation diffusion facilitator family pro... 108 2e-22
UniRef50_Q7PWD5 Cluster: ENSANGP00000006521; n=1; Anopheles gamb... 106 8e-22
UniRef50_UPI00003C04C2 Cluster: PREDICTED: similar to CG6672-PA;... 105 1e-21
UniRef50_A2FW10 Cluster: Cation efflux family protein; n=4; Tric... 104 4e-21
UniRef50_Q4T2T2 Cluster: Chromosome undetermined SCAF10190, whol... 103 5e-21
UniRef50_Q7QZ17 Cluster: GLP_464_49476_50732; n=1; Giardia lambl... 103 7e-21
UniRef50_Q2UAQ9 Cluster: Zn2+ transporter ZNT1 and related Cd2+/... 102 2e-20
UniRef50_A0E0R2 Cluster: Chromosome undetermined scaffold_72, wh... 101 2e-20
UniRef50_UPI0000F1F0D2 Cluster: PREDICTED: hypothetical protein;... 100 5e-20
UniRef50_UPI0000DD7936 Cluster: PREDICTED: similar to solute car... 99 9e-20
UniRef50_Q54QU8 Cluster: Putative uncharacterized protein; n=2; ... 99 9e-20
UniRef50_Q54F34 Cluster: Putative uncharacterized protein; n=1; ... 98 3e-19
UniRef50_A7NYR7 Cluster: Chromosome chr6 scaffold_3, whole genom... 97 5e-19
UniRef50_Q0EWA1 Cluster: Cation efflux transporter; n=1; Maripro... 94 4e-18
UniRef50_Q9VKA3 Cluster: CG31860-PA; n=4; Diptera|Rep: CG31860-P... 93 8e-18
UniRef50_Q7S9J7 Cluster: Putative uncharacterized protein NCU077... 93 8e-18
UniRef50_Q1E3Q4 Cluster: Predicted protein; n=1; Coccidioides im... 90 9e-17
UniRef50_Q4SHM2 Cluster: Chromosome 5 SCAF14581, whole genome sh... 89 1e-16
UniRef50_Q3SKU3 Cluster: Cation efflux protein; n=4; Proteobacte... 89 2e-16
UniRef50_A5VLM8 Cluster: Cation diffusion facilitator family tra... 89 2e-16
UniRef50_Q7NRV3 Cluster: Probable cation efflux system; n=1; Chr... 86 2e-15
UniRef50_Q1R0K1 Cluster: Cation diffusion facilitator family tra... 85 2e-15
UniRef50_O67168 Cluster: Cation efflux system; n=1; Aquifex aeol... 85 3e-15
UniRef50_A6SYW0 Cluster: Cobalt-zinc-cadmium resistance protein ... 85 3e-15
UniRef50_UPI0000499CA1 Cluster: cation diffusion facilitator fam... 84 5e-15
UniRef50_A0B5Z8 Cluster: Cation diffusion facilitator family tra... 84 6e-15
UniRef50_Q83EH0 Cluster: Cation-efflux family protein; n=3; Coxi... 83 8e-15
UniRef50_Q1GPY2 Cluster: Cation diffusion facilitator family tra... 83 8e-15
UniRef50_A4XA76 Cluster: Cation diffusion facilitator family tra... 83 8e-15
UniRef50_A3GEZ3 Cluster: Meiotic Sister-Chromatid recombination ... 83 8e-15
UniRef50_Q1H0B4 Cluster: Cation diffusion facilitator family tra... 83 1e-14
UniRef50_A4SX31 Cluster: Cation diffusion facilitator family tra... 83 1e-14
UniRef50_Q98H85 Cluster: Cation efflux system protein; n=8; Alph... 82 2e-14
UniRef50_Q6M5R5 Cluster: Co/Zn/Cd efflux system transmembrane pr... 82 2e-14
UniRef50_Q6NHN1 Cluster: Cation-efflux system integral membrane ... 81 4e-14
UniRef50_A0DLG1 Cluster: Chromosome undetermined scaffold_55, wh... 81 6e-14
UniRef50_A6X3Y0 Cluster: Cation diffusion facilitator family tra... 80 7e-14
UniRef50_A5DM54 Cluster: Putative uncharacterized protein; n=1; ... 80 7e-14
UniRef50_UPI0000DAE80F Cluster: hypothetical protein Rgryl_01001... 80 1e-13
UniRef50_Q5L2G4 Cluster: Cation efflux transporter; n=5; Bacilla... 80 1e-13
UniRef50_A5WCY6 Cluster: Cation diffusion facilitator family tra... 80 1e-13
UniRef50_Q1AYG3 Cluster: Cation diffusion facilitator family tra... 79 2e-13
UniRef50_Q8EZ48 Cluster: Cobalt-zinc-cadmium resistance protein ... 79 2e-13
UniRef50_A3UGA9 Cluster: Cation efflux protein; n=3; Proteobacte... 79 2e-13
UniRef50_Q97G32 Cluster: Co/Zn/Cd efflux system component; n=1; ... 78 3e-13
UniRef50_A1RH26 Cluster: Cation diffusion facilitator family tra... 78 3e-13
UniRef50_A4R597 Cluster: Putative uncharacterized protein; n=1; ... 78 3e-13
UniRef50_Q01NK8 Cluster: Cation diffusion facilitator family tra... 77 5e-13
UniRef50_Q8WQB6 Cluster: Putative uncharacterized protein; n=2; ... 77 5e-13
UniRef50_Q6D7E5 Cluster: Zinc transporter zitB; n=40; Enterobact... 77 5e-13
UniRef50_Q3VS68 Cluster: Cation efflux protein; n=2; Chlorobiace... 77 9e-13
UniRef50_A5ESK1 Cluster: Cation efflux system protein czcD; n=4;... 77 9e-13
UniRef50_A0LXC1 Cluster: CDF family cation efflux protein; n=3; ... 77 9e-13
UniRef50_Q8U3B2 Cluster: Cation efflux system protein; n=5; cell... 77 9e-13
UniRef50_Q9ZT63 Cluster: Metal tolerance protein 1 (AtMTP1) (Zin... 77 9e-13
UniRef50_UPI0000DB7E27 Cluster: PREDICTED: similar to CG31860-PA... 76 1e-12
UniRef50_O85143 Cluster: Transport protein; n=35; Bacteria|Rep: ... 76 1e-12
UniRef50_A4X1A6 Cluster: Cation diffusion facilitator family tra... 76 1e-12
UniRef50_A7HC19 Cluster: Cation diffusion facilitator family tra... 76 2e-12
UniRef50_A6SIM4 Cluster: Putative uncharacterized protein; n=2; ... 76 2e-12
UniRef50_A7HL40 Cluster: Cation diffusion facilitator family tra... 75 2e-12
UniRef50_A0NU32 Cluster: Cation efflux system protein; n=1; Stap... 75 2e-12
UniRef50_Q9PF12 Cluster: Cobalt-zinc-cadmium resistance protein;... 75 3e-12
UniRef50_Q8CNH2 Cluster: CzrB protein; n=3; Staphylococcus|Rep: ... 75 3e-12
UniRef50_Q2LY02 Cluster: Cobalt-zinc-cadmium resistance protein;... 75 3e-12
UniRef50_A3XRG5 Cluster: Cobalt/zinc/cadmium cation efflux pump ... 75 3e-12
UniRef50_Q4T2L9 Cluster: Chromosome undetermined SCAF10234, whol... 75 4e-12
UniRef50_Q8ERA7 Cluster: Cation efflux system permease; n=14; Ba... 74 5e-12
UniRef50_Q5NP70 Cluster: Cation efflux system protein; n=2; Zymo... 74 5e-12
UniRef50_Q74FW5 Cluster: Cation efflux family protein; n=7; Desu... 73 9e-12
UniRef50_Q1II24 Cluster: Cation diffusion facilitator family tra... 73 9e-12
UniRef50_Q6A8D8 Cluster: Cation-efflux transport protein; n=2; A... 73 1e-11
UniRef50_Q64SU7 Cluster: Cation efflux system protein; n=5; Bact... 73 1e-11
UniRef50_A2SD15 Cluster: Cation efflux system protein; n=1; Meth... 73 1e-11
UniRef50_Q22DR5 Cluster: Cation diffusion facilitator family tra... 73 2e-11
UniRef50_A6R777 Cluster: Predicted protein; n=2; Pezizomycotina|... 73 2e-11
UniRef50_Q9LXS1 Cluster: Metal tolerance protein A2; n=17; rosid... 73 2e-11
UniRef50_Q0ICB8 Cluster: Cation efflux system protein; n=2; Syne... 72 2e-11
UniRef50_Q1Q6G6 Cluster: Strongly similar to cation (Co/Zn/Cd) d... 72 3e-11
UniRef50_Q0AGJ2 Cluster: Cation diffusion facilitator family tra... 72 3e-11
UniRef50_A3VSL3 Cluster: Cation efflux protein; n=1; Parvularcul... 71 5e-11
UniRef50_A0JRX0 Cluster: Cation diffusion facilitator family tra... 71 5e-11
UniRef50_Q22GX2 Cluster: Cation diffusion facilitator family tra... 71 5e-11
UniRef50_A5E801 Cluster: Putative uncharacterized protein; n=1; ... 71 5e-11
UniRef50_Q8IWU4 Cluster: Zinc transporter 8; n=18; Tetrapoda|Rep... 71 5e-11
UniRef50_Q8KBG3 Cluster: Cation efflux family protein; n=5; Chlo... 71 6e-11
UniRef50_Q5FM42 Cluster: Cation efflux protein; n=5; Lactobacill... 71 6e-11
UniRef50_A0BG38 Cluster: Chromosome undetermined scaffold_105, w... 71 6e-11
UniRef50_Q5HTV1 Cluster: Cation efflux family protein; n=11; Cam... 70 8e-11
UniRef50_Q4ECE6 Cluster: Cation efflux family protein; n=12; Ric... 70 8e-11
UniRef50_P72068 Cluster: Putative uncharacterized protein; n=1; ... 70 8e-11
UniRef50_A6LME7 Cluster: Cation diffusion facilitator family tra... 70 8e-11
UniRef50_Q22541 Cluster: Putative uncharacterized protein; n=3; ... 70 8e-11
UniRef50_P13512 Cluster: Cobalt-zinc-cadmium resistance protein ... 70 8e-11
UniRef50_Q03ZB0 Cluster: Co/Zn/Cd efflux system component; n=1; ... 70 1e-10
UniRef50_A6Q136 Cluster: Cation efflux system protein, CDF famil... 70 1e-10
UniRef50_Q07XG6 Cluster: Cation diffusion facilitator family tra... 69 1e-10
UniRef50_O45923 Cluster: Putative uncharacterized protein ttm-1;... 69 1e-10
UniRef50_O14863 Cluster: Zinc transporter 4; n=33; Euteleostomi|... 69 1e-10
UniRef50_Q8F433 Cluster: Cobalt-zinc-cadmium resistance protein ... 69 2e-10
UniRef50_Q606W3 Cluster: Cation efflux family protein; n=2; Bact... 69 2e-10
UniRef50_Q5FQH8 Cluster: Cation efflux system protein; n=1; Gluc... 69 2e-10
UniRef50_A0VV15 Cluster: Cation diffusion facilitator family tra... 69 2e-10
UniRef50_A7I6Y5 Cluster: Cation diffusion facilitator family tra... 69 2e-10
UniRef50_Q5ZRY2 Cluster: Cation efflux system protein; n=4; Legi... 69 2e-10
UniRef50_Q5CSE6 Cluster: Cation diffusion facilitator like membr... 69 2e-10
UniRef50_A1B355 Cluster: Cation diffusion facilitator family tra... 68 3e-10
UniRef50_A0ZGF9 Cluster: Cation efflux system protein; n=1; Nodu... 68 3e-10
UniRef50_A6RG56 Cluster: Predicted protein; n=1; Ajellomyces cap... 68 4e-10
UniRef50_A4M7M1 Cluster: Cation diffusion facilitator family tra... 67 6e-10
UniRef50_A0FTM8 Cluster: Cation diffusion facilitator family tra... 67 7e-10
UniRef50_Q4D6N1 Cluster: Cation transporter protein, putative; n... 67 7e-10
UniRef50_A4HFQ2 Cluster: Cation transporter, putative; n=3; Leis... 67 7e-10
UniRef50_Q4P174 Cluster: Putative uncharacterized protein; n=1; ... 67 7e-10
UniRef50_Q7UMH1 Cluster: Cation efflux system protein; n=1; Pire... 66 1e-09
UniRef50_Q0BUV7 Cluster: Cation efflux system protein; n=1; Gran... 66 1e-09
UniRef50_Q04D37 Cluster: Co/Zn/Cd efflux system component; n=2; ... 66 1e-09
UniRef50_A1UA75 Cluster: Cation diffusion facilitator family tra... 66 1e-09
UniRef50_Q99726 Cluster: Zinc transporter 3; n=23; Mammalia|Rep:... 66 1e-09
UniRef50_UPI0000E4799B Cluster: PREDICTED: similar to zinc trans... 66 1e-09
UniRef50_UPI0000499414 Cluster: cation efflux protein; n=1; Enta... 66 1e-09
UniRef50_Q1ZSN3 Cluster: Cation diffusion facilitator family tra... 66 1e-09
UniRef50_Q57YU8 Cluster: Metal-ion transporter, putative; n=4; T... 66 1e-09
UniRef50_UPI00006CA446 Cluster: cation diffusion facilitator fam... 66 2e-09
UniRef50_Q8G4R7 Cluster: Probable cation efflux protein; n=4; Bi... 65 2e-09
UniRef50_Q7NDR3 Cluster: Gll4169 protein; n=3; Bacteria|Rep: Gll... 65 3e-09
UniRef50_Q30S31 Cluster: Cation efflux protein; n=1; Thiomicrosp... 65 3e-09
UniRef50_Q2GIB0 Cluster: Cation efflux family protein; n=1; Anap... 64 4e-09
UniRef50_Q5B283 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09
UniRef50_UPI0000D5546C Cluster: PREDICTED: similar to solute car... 64 5e-09
UniRef50_UPI00006CBB53 Cluster: cation diffusion facilitator fam... 64 5e-09
UniRef50_A0AW44 Cluster: Cation diffusion facilitator family tra... 64 5e-09
UniRef50_Q8TRQ7 Cluster: Cation efflux system protein; n=2; Meth... 64 5e-09
UniRef50_Q9BRI3 Cluster: Zinc transporter 2; n=34; Eumetazoa|Rep... 64 5e-09
UniRef50_UPI0000D56740 Cluster: PREDICTED: similar to T18D3.3; n... 64 7e-09
UniRef50_Q4REH2 Cluster: Chromosome 10 SCAF15123, whole genome s... 64 7e-09
UniRef50_A7B9C7 Cluster: Putative uncharacterized protein; n=1; ... 64 7e-09
UniRef50_Q4DHZ0 Cluster: Zinc transporter, putative; n=2; Trypan... 64 7e-09
UniRef50_Q9CCX3 Cluster: Putative cation-efflux transporter comp... 63 1e-08
UniRef50_A3XEG4 Cluster: Cation efflux system protein; n=9; Prot... 63 1e-08
UniRef50_A3ETR2 Cluster: Co/Zn/Cd efflux system component; n=4; ... 63 1e-08
UniRef50_Q7PWF8 Cluster: ENSANGP00000019448; n=3; Culicidae|Rep:... 63 1e-08
UniRef50_Q6ICY4 Cluster: Metal tolerance protein C2; n=7; Magnol... 63 1e-08
UniRef50_Q5LTM6 Cluster: Cation efflux system protein; n=13; Alp... 62 2e-08
UniRef50_A0J3Y1 Cluster: Cation diffusion facilitator family tra... 62 2e-08
UniRef50_Q9V471 Cluster: CG3994-PA, isoform A; n=3; Sophophora|R... 62 2e-08
UniRef50_Q4WLB1 Cluster: CDF zinc transporter (Msc2), putaitve; ... 62 2e-08
UniRef50_Q5V738 Cluster: Cation efflux system protein; n=1; Halo... 62 2e-08
UniRef50_Q9ABC7 Cluster: Cation efflux family protein; n=35; Bac... 62 3e-08
UniRef50_O67851 Cluster: Putative uncharacterized protein; n=1; ... 61 4e-08
UniRef50_A1IE74 Cluster: Cobalt-zinc-cadmium resistance protein;... 61 4e-08
UniRef50_Q0C865 Cluster: Putative uncharacterized protein; n=1; ... 61 5e-08
UniRef50_UPI000023F444 Cluster: hypothetical protein FG09632.1; ... 60 6e-08
UniRef50_Q8YT81 Cluster: Cation-efflux system membrane protein; ... 60 6e-08
UniRef50_Q2NBG7 Cluster: Cation efflux system protein; n=3; Prot... 60 6e-08
UniRef50_Q7S953 Cluster: Putative uncharacterized protein NCU072... 60 6e-08
UniRef50_Q83MV9 Cluster: Cation efflux protein; n=2; Tropheryma ... 60 9e-08
UniRef50_Q2J9T2 Cluster: Cation diffusion facilitator family tra... 60 9e-08
UniRef50_A1SIT8 Cluster: Cation diffusion facilitator family tra... 60 1e-07
UniRef50_Q9HGQ3 Cluster: Uncharacterized transporter C17D4.03c; ... 60 1e-07
UniRef50_Q4Q622 Cluster: Zinc transporter-like protein; n=3; Lei... 59 1e-07
UniRef50_Q5KCD4 Cluster: Cation:cation antiporter, putative; n=2... 59 2e-07
UniRef50_A5UNR6 Cluster: Heavy metal cation (Co/Zn/Cd) efflux sy... 59 2e-07
UniRef50_Q2JWZ6 Cluster: Cation transporter, cation diffusion fa... 58 3e-07
UniRef50_Q4Y0W9 Cluster: Zinc transporter, putative; n=3; Plasmo... 58 3e-07
UniRef50_Q8SQT3 Cluster: ZINC TRANSPORTER; n=1; Encephalitozoon ... 58 3e-07
UniRef50_A1RH69 Cluster: Cation diffusion facilitator family tra... 58 5e-07
UniRef50_Q55E98 Cluster: Putative uncharacterized protein; n=1; ... 58 5e-07
UniRef50_A7DRF6 Cluster: Cation diffusion facilitator family tra... 57 6e-07
UniRef50_Q97LF5 Cluster: C-terminal region cation efflux system ... 57 8e-07
UniRef50_Q6ML10 Cluster: Cation-efflux system membrane protein; ... 57 8e-07
UniRef50_A6BDG0 Cluster: Putative uncharacterized protein; n=2; ... 57 8e-07
UniRef50_Q3ZWB7 Cluster: Cation efflux family protein; n=2; Deha... 56 1e-06
UniRef50_Q6QSW0 Cluster: Cation efflux facilitator; n=1; Enteroc... 56 1e-06
UniRef50_A0RLZ7 Cluster: Cation efflux family protein; n=1; Camp... 56 1e-06
UniRef50_A7RHI7 Cluster: Predicted protein; n=1; Nematostella ve... 56 1e-06
UniRef50_A5JZM5 Cluster: Cation diffusion facilitator transporte... 56 1e-06
UniRef50_Q55JC6 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06
UniRef50_A6UWS0 Cluster: Cation diffusion facilitator family tra... 56 1e-06
UniRef50_UPI00015BD034 Cluster: UPI00015BD034 related cluster; n... 56 2e-06
UniRef50_P93574 Cluster: 123.pep; n=4; Magnoliophyta|Rep: 123.pe... 56 2e-06
UniRef50_A5ULB6 Cluster: Cation efflux system protein; n=1; Meth... 56 2e-06
UniRef50_Q12M16 Cluster: Cation diffusion facilitator family tra... 55 2e-06
UniRef50_Q8IBU1 Cluster: Zinc transporter, putative; n=2; Plasmo... 55 2e-06
UniRef50_Q0UF07 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_Q02XW1 Cluster: Co/Zn/Cd efflux system component; n=3; ... 54 4e-06
UniRef50_A4C4Q3 Cluster: Putative CzcD, Co/Zn/Cd efflux system c... 54 4e-06
UniRef50_Q9KDH5 Cluster: Cation efflux system; n=4; Bacillaceae|... 54 6e-06
UniRef50_A6SZ19 Cluster: Cobalt-zinc-cadmium resistance protein ... 54 7e-06
UniRef50_A6LXL8 Cluster: Cation diffusion facilitator family tra... 54 7e-06
UniRef50_A1W9S8 Cluster: Cation diffusion facilitator family tra... 53 1e-05
UniRef50_Q8ZUM0 Cluster: Cation efflux system protein; n=1; Pyro... 53 1e-05
UniRef50_UPI00015BCCB5 Cluster: UPI00015BCCB5 related cluster; n... 53 1e-05
UniRef50_Q7MUS7 Cluster: Heavy metal efflux pump, CzcD family; n... 53 1e-05
UniRef50_A7CNS8 Cluster: Cation diffusion facilitator family tra... 53 1e-05
UniRef50_A5KR43 Cluster: Putative uncharacterized protein; n=2; ... 53 1e-05
UniRef50_A3RS25 Cluster: CzcD; n=3; Ralstonia solanacearum|Rep: ... 53 1e-05
UniRef50_A1ZDC5 Cluster: Heavy metal efflux pump, CzcD family; n... 53 1e-05
UniRef50_Q97WH2 Cluster: Probable cation transport protein; n=1;... 53 1e-05
UniRef50_UPI00005852CD Cluster: PREDICTED: similar to solute car... 52 2e-05
UniRef50_Q8T0G1 Cluster: LD05335p; n=1; Drosophila melanogaster|... 52 2e-05
UniRef50_A7TSV1 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_A5G751 Cluster: Cation diffusion facilitator family tra... 52 2e-05
UniRef50_A1FMN4 Cluster: Cation diffusion facilitator family tra... 52 2e-05
UniRef50_Q4QD72 Cluster: Cation transporter, putative; n=4; Leis... 52 2e-05
UniRef50_Q03455 Cluster: Probable zinc transporter MSC2; n=2; Sa... 52 2e-05
UniRef50_Q97NZ2 Cluster: Cation efflux system protein; n=27; Str... 52 3e-05
UniRef50_Q57891 Cluster: Uncharacterized transporter MJ0449; n=4... 52 3e-05
UniRef50_A3PRE9 Cluster: Cation diffusion facilitator family tra... 50 7e-05
UniRef50_Q5XCQ6 Cluster: Cobalt-zinc-cadmium resistance protein;... 50 1e-04
UniRef50_Q11KC0 Cluster: Cation diffusion facilitator family tra... 50 1e-04
UniRef50_A5FSC2 Cluster: Cation diffusion facilitator family tra... 49 2e-04
UniRef50_A4M6M7 Cluster: Cation diffusion facilitator family tra... 49 2e-04
UniRef50_Q6CJ78 Cluster: Similarities with sgd|S0002613 Saccharo... 49 2e-04
UniRef50_Q2H1F8 Cluster: Putative uncharacterized protein; n=1; ... 49 2e-04
UniRef50_O27915 Cluster: Cation efflux system protein; n=1; Meth... 49 2e-04
UniRef50_UPI00015A5CA2 Cluster: Zinc transporter 4 (ZnT-4) (Solu... 49 2e-04
UniRef50_A1VZU0 Cluster: Cation efflux family protein; n=12; Cam... 49 2e-04
UniRef50_A1VD81 Cluster: Cation diffusion facilitator family tra... 49 2e-04
UniRef50_A1S0U9 Cluster: Cation diffusion facilitator family tra... 49 2e-04
UniRef50_Q6FU89 Cluster: Similar to tr|Q03455 Saccharomyces cere... 48 4e-04
UniRef50_Q6CBI9 Cluster: Similarities with tr|Q03455 Saccharomyc... 48 4e-04
UniRef50_Q81QV5 Cluster: Cation efflux family protein; n=19; Fir... 48 5e-04
UniRef50_Q18YB5 Cluster: Cation diffusion facilitator family tra... 48 5e-04
UniRef50_A6LJ50 Cluster: Cation diffusion facilitator family tra... 48 5e-04
UniRef50_Q6NXT4 Cluster: Solute carrier family 30 member 6; n=36... 48 5e-04
UniRef50_Q8RDD5 Cluster: Predicted Co/Zn/Cd cation transporters;... 47 6e-04
UniRef50_Q1NQB8 Cluster: Cation efflux protein; n=2; delta prote... 47 6e-04
UniRef50_A6PM43 Cluster: Cation diffusion facilitator family tra... 47 6e-04
UniRef50_A1RJA2 Cluster: Cation diffusion facilitator family tra... 47 6e-04
UniRef50_A0KXE1 Cluster: Cation diffusion facilitator family tra... 47 6e-04
UniRef50_Q8D6D0 Cluster: Co/Zn/Cd efflux system component; n=8; ... 47 9e-04
UniRef50_A0YFC6 Cluster: Cation transporter, cation diffusion fa... 47 9e-04
UniRef50_Q9CLA2 Cluster: CzcD; n=8; Pasteurellaceae|Rep: CzcD - ... 46 0.001
UniRef50_A6LZH5 Cluster: Cation diffusion facilitator family tra... 46 0.001
UniRef50_Q9KEY7 Cluster: Cation efflux system; n=11; Bacillus|Re... 46 0.002
UniRef50_A4EAI9 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002
UniRef50_A4BEK1 Cluster: Predicted Co/Zn/Cd cation transporter; ... 46 0.002
UniRef50_A1H9T8 Cluster: Cation efflux system protein; n=19; Pro... 46 0.002
UniRef50_Q99JQ3 Cluster: Slc30a6 protein; n=2; Euteleostomi|Rep:... 45 0.003
UniRef50_A6NR09 Cluster: Putative uncharacterized protein; n=1; ... 45 0.003
UniRef50_A6LYH8 Cluster: Cation diffusion facilitator family tra... 45 0.003
UniRef50_Q0AY41 Cluster: Putative cation efflux system protein; ... 45 0.003
UniRef50_A7BVM0 Cluster: Cation efflux protein; n=3; Beggiatoa s... 45 0.003
UniRef50_A0V364 Cluster: Cation diffusion facilitator family tra... 45 0.003
UniRef50_Q1IPF4 Cluster: Cation diffusion facilitator family tra... 44 0.005
UniRef50_A0LKX9 Cluster: Cation diffusion facilitator family tra... 44 0.005
UniRef50_O27240 Cluster: Possible cation transporter; n=1; Metha... 44 0.005
UniRef50_Q7MT89 Cluster: Cation efflux family protein; n=3; Bact... 44 0.006
UniRef50_Q5DCM5 Cluster: SJCHGC09275 protein; n=1; Schistosoma j... 44 0.006
UniRef50_Q45EL5 Cluster: Similar to transporter of divalent cati... 44 0.006
UniRef50_Q8TT88 Cluster: Cation efflux system protein; n=4; Meth... 44 0.006
UniRef50_Q8Q0G9 Cluster: Cobalt-zinc-cadmium resistance protein;... 44 0.006
UniRef50_UPI0000383D2E Cluster: COG0053: Predicted Co/Zn/Cd cati... 44 0.008
UniRef50_Q97MV4 Cluster: Predicted Co/Zn/Cd cation transporter; ... 44 0.008
UniRef50_Q8VLX7 Cluster: CzrB protein; n=3; Thermus thermophilus... 44 0.008
UniRef50_A5ZXZ3 Cluster: Putative uncharacterized protein; n=1; ... 44 0.008
UniRef50_A5W938 Cluster: Cation diffusion facilitator family tra... 44 0.008
UniRef50_A4E9J2 Cluster: Putative uncharacterized protein; n=1; ... 44 0.008
UniRef50_A0QIJ5 Cluster: Cation efflux family protein; n=3; Myco... 44 0.008
UniRef50_Q4DK06 Cluster: Cation transporter, putative; n=3; Tryp... 44 0.008
UniRef50_Q2SCG7 Cluster: Predicted Co/Zn/Cd cation transporters;... 43 0.011
UniRef50_A3VV32 Cluster: Cation efflux family protein; n=1; Parv... 43 0.011
UniRef50_A3AD18 Cluster: Putative uncharacterized protein; n=2; ... 43 0.011
UniRef50_Q8ZYX3 Cluster: Cation efflux system protein, conjectur... 43 0.011
UniRef50_Q83BX5 Cluster: Cation-efflux family protein; n=2; Coxi... 43 0.014
UniRef50_Q2RHV4 Cluster: Cation diffusion facilitator family tra... 43 0.014
UniRef50_A5Z978 Cluster: Putative uncharacterized protein; n=2; ... 43 0.014
UniRef50_Q4JC20 Cluster: Cation efflux integral membrane protein... 43 0.014
UniRef50_Q62FW4 Cluster: Cation efflux family protein; n=48; Pro... 42 0.018
UniRef50_A6TSV8 Cluster: Cation diffusion facilitator family tra... 42 0.018
UniRef50_A5IIQ7 Cluster: Cation diffusion facilitator family tra... 42 0.018
UniRef50_Q0W2J0 Cluster: Predicted cation efflux protein; n=3; E... 42 0.018
UniRef50_Q97K27 Cluster: Cation efflux system protein; n=1; Clos... 42 0.024
UniRef50_Q8KEZ4 Cluster: Cation efflux family protein; n=6; Chlo... 42 0.024
UniRef50_P96691 Cluster: YdfM protein; n=2; Bacillus|Rep: YdfM p... 42 0.024
UniRef50_Q2BMX3 Cluster: Cation-efflux family protein; n=1; Nept... 42 0.024
UniRef50_Q03YB0 Cluster: Predicted Co/Zn/Cd cation transporter; ... 42 0.024
UniRef50_A5TUV7 Cluster: Possible CDF family cation diffusion fa... 42 0.024
UniRef50_A0Z3U7 Cluster: Ferrous iron efflux protein F; n=4; Gam... 42 0.024
UniRef50_A0L9V8 Cluster: Cation diffusion facilitator family tra... 42 0.024
UniRef50_A7PTX2 Cluster: Chromosome chr7 scaffold_31, whole geno... 42 0.024
UniRef50_Q8PTD7 Cluster: Cobalt-zinc-cadmium resistance protein;... 42 0.024
UniRef50_Q6NE50 Cluster: Magnetosome protein MamB; n=5; Magnetos... 42 0.032
UniRef50_A6VZC2 Cluster: Cation diffusion facilitator family tra... 42 0.032
UniRef50_A6CU38 Cluster: Cation efflux family protein; probable ... 42 0.032
UniRef50_A5EV87 Cluster: Cation efflux family protein; n=1; Dich... 42 0.032
UniRef50_Q4PIB2 Cluster: Putative uncharacterized protein; n=1; ... 42 0.032
UniRef50_A3CRV2 Cluster: Cation diffusion facilitator family tra... 42 0.032
UniRef50_Q89K61 Cluster: Cation efflux system protein; n=4; Brad... 41 0.042
UniRef50_Q1JWM6 Cluster: Cation diffusion facilitator family tra... 41 0.042
UniRef50_A7GZ19 Cluster: Pantothenate metabolism flavoprotein; n... 41 0.042
UniRef50_A4J2G0 Cluster: Cation diffusion facilitator family tra... 41 0.042
UniRef50_A0NZQ3 Cluster: Cation efflux transporter, CDF family p... 41 0.042
UniRef50_P46348 Cluster: Uncharacterized transporter yeaB; n=19;... 41 0.042
UniRef50_Q08970 Cluster: Mitochondrial metal transporter 2, mito... 41 0.042
UniRef50_UPI0000DAE7E5 Cluster: hypothetical protein Rgryl_01001... 41 0.056
UniRef50_Q97PQ1 Cluster: Cation efflux family protein; n=41; Str... 41 0.056
UniRef50_Q2AI61 Cluster: Cation efflux protein; n=1; Halothermot... 41 0.056
UniRef50_A0LCE7 Cluster: Cation diffusion facilitator family tra... 41 0.056
UniRef50_O30282 Cluster: Conserved hypothetical transmembrane pr... 41 0.056
UniRef50_A1RZ87 Cluster: Cation diffusion facilitator family tra... 41 0.056
UniRef50_UPI000049A2B4 Cluster: cation diffusion facilitator fam... 40 0.074
UniRef50_Q65T10 Cluster: MMT1 protein; n=1; Mannheimia succinici... 40 0.074
UniRef50_Q3AES4 Cluster: Cation efflux family protein; n=1; Carb... 40 0.074
UniRef50_A1HSL0 Cluster: Cation diffusion facilitator family tra... 40 0.074
UniRef50_Q6CT16 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 40 0.074
UniRef50_Q8L725 Cluster: Metal tolerance protein C1; n=2; Arabid... 40 0.074
UniRef50_Q3A4F2 Cluster: Putative transport system permease prot... 40 0.098
UniRef50_Q31EH6 Cluster: Cation diffusion facilitator (CDF) fami... 40 0.098
UniRef50_A6BIC1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.098
UniRef50_Q6A6E4 Cluster: Predicted Co/Zn/Cd cation transporter; ... 40 0.13
UniRef50_Q5R141 Cluster: Co/Zn/Cd efflux system component; n=4; ... 40 0.13
UniRef50_Q9ALR5 Cluster: CztD; n=1; Pseudomonas fluorescens|Rep:... 40 0.13
UniRef50_Q1Q6L8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.13
UniRef50_A1K3F1 Cluster: Putative cobalt-zinc-cadmium resistance... 40 0.13
UniRef50_Q660Q6 Cluster: Conserved hypothetical integral membran... 39 0.17
UniRef50_A7I5F3 Cluster: Cation diffusion facilitator family tra... 39 0.17
UniRef50_Q2NTU9 Cluster: Putative transport protein; n=1; Sodali... 39 0.23
UniRef50_Q11X42 Cluster: Cation efflux system protein; n=8; Bact... 39 0.23
UniRef50_Q0TS00 Cluster: Cation efflux family protein; n=4; Clos... 39 0.23
UniRef50_Q54N31 Cluster: Putative uncharacterized protein; n=1; ... 39 0.23
UniRef50_Q96YR3 Cluster: Putative uncharacterized protein ST2110... 39 0.23
UniRef50_Q5UZ15 Cluster: Cation efflux protein; n=1; Haloarcula ... 39 0.23
UniRef50_Q03218 Cluster: Mitochondrial metal transporter 1, mito... 39 0.23
UniRef50_Q21JA9 Cluster: Co/Zn/Cd efflux system component; n=1; ... 38 0.30
UniRef50_A5G746 Cluster: Cation diffusion facilitator family tra... 38 0.30
UniRef50_A3M2K9 Cluster: Putative cation efflux system protein; ... 38 0.30
UniRef50_Q8TV30 Cluster: Predicted Co/Zn/Cd cation transporter; ... 38 0.30
UniRef50_Q6LZI4 Cluster: Cation efflux protein; n=11; cellular o... 38 0.30
UniRef50_Q2RR20 Cluster: Cation efflux protein; n=7; Proteobacte... 38 0.40
UniRef50_A1IAH4 Cluster: Cation diffusion facilitator family tra... 38 0.40
UniRef50_Q73Q10 Cluster: Cation efflux family protein; n=1; Trep... 38 0.52
UniRef50_Q3E481 Cluster: Cation efflux protein; n=5; Bacteria|Re... 38 0.52
UniRef50_A1AWZ0 Cluster: Cation diffusion facilitator family tra... 38 0.52
UniRef50_Q59MA8 Cluster: Potential cation efflux family member; ... 38 0.52
UniRef50_Q479I8 Cluster: Cation efflux protein; n=1; Dechloromon... 37 0.69
UniRef50_A1SH46 Cluster: Cation diffusion facilitator family tra... 37 0.69
UniRef50_A0Q5V4 Cluster: Predicted Co/Zn/Cd cation transporter; ... 37 0.69
UniRef50_A2QMS3 Cluster: Function: MMT1 of S. cerevisiae is invo... 37 0.69
UniRef50_Q97WI8 Cluster: Transport protein, hypothetical; n=1; S... 37 0.69
UniRef50_P74068 Cluster: Uncharacterized transporter sll1263; n=... 37 0.69
UniRef50_Q837I0 Cluster: Cation efflux family protein; n=1; Ente... 37 0.91
UniRef50_A5WDB2 Cluster: Cation efflux protein; n=14; Bacteria|R... 37 0.91
UniRef50_A0LLF0 Cluster: Cation diffusion facilitator family tra... 37 0.91
UniRef50_Q5ZTN8 Cluster: Cobalt zinc cadmium cation transporter;... 36 1.2
UniRef50_Q1EYD3 Cluster: Cation efflux protein precursor; n=1; C... 36 1.2
UniRef50_A7HCY0 Cluster: Co/Zn/Cd efflux system component; n=4; ... 36 1.2
UniRef50_A7AEG5 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_A6Q3V3 Cluster: Cation efflux protein; n=2; Epsilonprot... 36 1.2
UniRef50_A6EF02 Cluster: Cation efflux system protein; n=1; Pedo... 36 1.2
UniRef50_A4YF73 Cluster: Cation diffusion facilitator family tra... 36 1.2
UniRef50_Q5ZTX4 Cluster: Cation efflux family protein; n=4; Legi... 36 1.6
UniRef50_Q4IXC3 Cluster: Cation efflux protein; n=18; Pseudomona... 36 1.6
UniRef50_A1WYJ4 Cluster: Cation diffusion facilitator family tra... 36 1.6
UniRef50_A1DEK4 Cluster: Cation efflux family protein, putative;... 36 1.6
UniRef50_Q47VY8 Cluster: Cation efflux family protein; n=1; Colw... 36 2.1
UniRef50_UPI00003C852F Cluster: hypothetical protein Faci_030012... 35 2.8
UniRef50_Q1LHU8 Cluster: Cation diffusion facilitator family tra... 35 2.8
UniRef50_A7JSP7 Cluster: CDF family cation diffusion facilitator... 35 2.8
UniRef50_O59758 Cluster: Mitochondrial iron ion transporter; n=1... 35 2.8
UniRef50_Q0BW07 Cluster: Cobalt-zinc-cadmium resistance protein ... 35 3.7
UniRef50_A0RND9 Cluster: Ferrous-iron efflux pump FieF; n=1; Cam... 35 3.7
UniRef50_O18027 Cluster: Putative uncharacterized protein str-12... 35 3.7
UniRef50_UPI0000E4758C Cluster: PREDICTED: similar to Solute car... 34 4.9
UniRef50_Q67K51 Cluster: Cation efflux system protein; n=1; Symb... 34 4.9
UniRef50_Q1NE81 Cluster: Cation efflux protein; n=1; Sphingomona... 34 4.9
UniRef50_Q0FXT8 Cluster: Putative uncharacterized protein; n=1; ... 34 4.9
UniRef50_A0AWY3 Cluster: Cation diffusion facilitator family tra... 34 4.9
UniRef50_O28143 Cluster: Conserved hypothetical transmembrane pr... 34 4.9
UniRef50_Q8KB34 Cluster: Cation efflux family protein; n=1; Chlo... 34 6.4
UniRef50_Q6MCR1 Cluster: Putative cation efflux system protein; ... 34 6.4
UniRef50_A5DLU7 Cluster: Putative uncharacterized protein; n=1; ... 34 6.4
UniRef50_Q8PXZ0 Cluster: Cation efflux system protein; n=4; Meth... 34 6.4
UniRef50_P55237 Cluster: Uncharacterized protein in glgB 5'regio... 34 6.4
UniRef50_UPI00015B5C26 Cluster: PREDICTED: hypothetical protein;... 33 8.5
UniRef50_Q98M07 Cluster: Probable membrane transport protein; n=... 33 8.5
UniRef50_A1AQF0 Cluster: Cation diffusion facilitator family tra... 33 8.5
UniRef50_Q8I1Q4 Cluster: Putative uncharacterized protein PFD088... 33 8.5
UniRef50_Q8TP38 Cluster: Cation efflux system protein; n=3; Meth... 33 8.5
>UniRef50_UPI00015B61F4 Cluster: PREDICTED: similar to GA14626-PA;
n=2; Apocrita|Rep: PREDICTED: similar to GA14626-PA -
Nasonia vitripennis
Length = 2810
Score = 438 bits (1078), Expect = e-121
Identities = 220/339 (64%), Positives = 252/339 (74%), Gaps = 6/339 (1%)
Query: 1 MGRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM 60
MGR++GKKCRLL ML LT FF VE+IVGY+TNSMAL+ADSFHMLSDVAAL++AFLSVKM
Sbjct: 2358 MGRFTGKKCRLLTMLWLTAFFFLVEIIVGYVTNSMALIADSFHMLSDVAALVVAFLSVKM 2417
Query: 61 SPKKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXX 120
SPKKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEA KRFIE E IH+ K
Sbjct: 2418 SPKKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEACKRFIEVEKIHDAKLLVVVGAL 2477
Query: 121 XXXXXXXXXXXXHVPPPSNVRHLTEIVNSN--ADRALGHNSTDNEET---DEMVKKAKTQ 175
H + H I S+ +G + +N+ET +K+A
Sbjct: 2478 GLVVNLVGLCLFHEHGHGHGGHSHSISRSHNRLSTLVGTDDNENDETYRPPSPLKRAGGH 2537
Query: 176 NHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXX 235
H S D MNM+GVFLHVLSDALGS+IV+ SAL+VWLT W+Y+ YIDP
Sbjct: 2538 GHGHGHSHGDGSQMNMRGVFLHVLSDALGSVIVIVSALIVWLTNWEYRFYIDPALSLLLV 2597
Query: 236 XXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRR-LKNVEGVMAVHEFHVWQLAGDRIIA 294
WPLL+ES+LILLQTVPTHIQVDAIQ+R L+N++GV+AVHEFHVWQLAGDRIIA
Sbjct: 2598 MLILKSVWPLLQESALILLQTVPTHIQVDAIQQRLLENIDGVLAVHEFHVWQLAGDRIIA 2657
Query: 295 SAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFVE 333
SAHIRCRNLSEYMKIAE+VKEFFHNEGIHSTTIQPEF++
Sbjct: 2658 SAHIRCRNLSEYMKIAEQVKEFFHNEGIHSTTIQPEFID 2696
>UniRef50_Q7K3K5 Cluster: LD22804p; n=7; Endopterygota|Rep: LD22804p
- Drosophila melanogaster (Fruit fly)
Length = 449
Score = 427 bits (1052), Expect = e-118
Identities = 220/340 (64%), Positives = 248/340 (72%), Gaps = 7/340 (2%)
Query: 1 MGRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM 60
M +YSGKKCRLL M+ LT FFFVE+IVGY+TNSMALVADSFHML D+AAL+I+FLSVKM
Sbjct: 1 MAKYSGKKCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKM 60
Query: 61 SPKKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXX 120
SPKKWSKNTFGWARAEVLGALVNAVFLVALCFSIT+EA KRFIE E IH P+
Sbjct: 61 SPKKWSKNTFGWARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGAL 120
Query: 121 XXXXXXXXXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTD---NEETDEMVKKAKTQ-- 175
+ + + N R + D +E+ D +K K +
Sbjct: 121 GLLVNVIGLCLLYEHGGHHGHSHGGGLTRNHSRLTELANMDEGEDEQNDFAYEKQKEKAP 180
Query: 176 -NHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXX 234
S S DPG MNM+G FLHVLSDALGS+IVV SA+VVW TEWKY++Y+DP
Sbjct: 181 VKKSSHGHSHDPGQMNMRGAFLHVLSDALGSIIVVISAVVVWKTEWKYRYYMDPALSIVL 240
Query: 235 XXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRR-LKNVEGVMAVHEFHVWQLAGDRII 293
WPLLRES+LILLQTVPTHIQVDAIQ+R L+ V+GV+AVHEFHVWQLAGDRII
Sbjct: 241 VVLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRII 300
Query: 294 ASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFVE 333
ASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEF E
Sbjct: 301 ASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFSE 340
>UniRef50_UPI0000E49D68 Cluster: PREDICTED: similar to CG17723-PA
isoform 1; n=3; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to CG17723-PA isoform 1 -
Strongylocentrotus purpuratus
Length = 457
Score = 271 bits (665), Expect = 2e-71
Identities = 139/334 (41%), Positives = 198/334 (59%), Gaps = 6/334 (1%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
S K CRL+ M+ LT FFFVEL VGYIT+S+ALVADSFHMLSD+ ALI+ F++V+ + +
Sbjct: 3 STKSCRLMTMMVLTASFFFVELSVGYITHSLALVADSFHMLSDIIALIVGFVAVRYAKRD 62
Query: 65 WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXX 124
KNT+GW RAEV+GALVNAVFL ALCF+I V+A++R ++ + I +P+
Sbjct: 63 TPKNTYGWQRAEVVGALVNAVFLFALCFTILVDAIERLVQGDKIKDPRLVLIVGGVGLAV 122
Query: 125 XXXXXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSS 184
+ V +R N T ++ + K K + +++
Sbjct: 123 NLLGILLFSSHGGGHGHSHASSVKEPEERVALANGTKGQDDLNIYKYTKKSDKSKVTTNT 182
Query: 185 ---DPG--HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXX 239
P +NM+GVFLHVL DALGS++V+ SALVV + + +DP
Sbjct: 183 FYHSPSAQQLNMRGVFLHVLGDALGSVVVIISALVVMFADGDWVFCVDPVLSILIVIIIS 242
Query: 240 XXXWPLLRESSLILLQTVPTHIQVDAIQRRLK-NVEGVMAVHEFHVWQLAGDRIIASAHI 298
WPL ++SS+ILLQ++PT I ++ I ++L+ + +HEFHVWQL G ++IA+ HI
Sbjct: 243 TTTWPLFKQSSMILLQSIPTGIDIEDIDKKLREECSYIDNIHEFHVWQLTGSKLIATLHI 302
Query: 299 RCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFV 332
+L EY K+ E+ + H EGIHSTTIQPEF+
Sbjct: 303 SVSSLEEYGKVIEQATKILHQEGIHSTTIQPEFI 336
>UniRef50_Q75D95 Cluster: ABR129Cp; n=2; Saccharomycetaceae|Rep:
ABR129Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 423
Score = 211 bits (515), Expect = 2e-53
Identities = 123/365 (33%), Positives = 195/365 (53%), Gaps = 28/365 (7%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
S K+ R++ +L L FF +E+I+GY +S+AL+ADSFHML+D+ +LI+A +V ++ +
Sbjct: 3 SNKEIRIVSLLVLDTVFFLLEIIIGYTVHSLALIADSFHMLNDIVSLIVALWAVNVAKTR 62
Query: 65 W--SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXX 122
++ T+GW RAE+LGAL+NAVFL+ALC SI +EA++RF E + + NP+
Sbjct: 63 NPDARYTYGWKRAEILGALINAVFLIALCVSILIEAIQRFFEPQEVKNPQLILYVGTAGL 122
Query: 123 XXXXXXXXXXHVPPPSNVRHLT-------EIVNSNADRALGHNSTDNEET-DEMVKKAKT 174
H S+ T +S++ H D E E + A
Sbjct: 123 LSNILGLFLFHEHGHSHSHGTTGEDMEAHSSSHSHSHHIGSHLHEDEPEAIQEFLPAAVV 182
Query: 175 QNHKSCKSSSDP----------GH------MNMKGVFLHVLSDALGSLIVVGSALVVWLT 218
+ + S + P H +NM GVFLHVL DALG++ V+ +A+ +W T
Sbjct: 183 ERYMSSSDENTPLVKDHDHKHSAHGADHRSLNMHGVFLHVLGDALGNVGVMLTAIFIWKT 242
Query: 219 EWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMA 278
++ +++Y DP PL R++S ILLQ P+ I D I+ ++ + ++
Sbjct: 243 DYSWRYYSDPFVSLVITCIIFSSALPLSRKASRILLQATPSSISADEIKGKILAIPVAIS 302
Query: 279 VHEFHVWQLAGDRIIASAHIRCR-NLSEYMKIAEKVKEFFHNEGIHSTTIQPEFVEGPQD 337
VH+FH+W L IAS H++ Y+ A+ ++ FH GIHS T+QPEF+ G +D
Sbjct: 303 VHDFHIWNLTETFSIASIHVQVDCGQDSYIGTAKVIRSIFHRYGIHSATVQPEFI-GSRD 361
Query: 338 ENEVS 342
++ S
Sbjct: 362 VSDDS 366
>UniRef50_UPI000049966E Cluster: cation diffusion facilitator family
transporter; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
cation diffusion facilitator family transporter -
Entamoeba histolytica HM-1:IMSS
Length = 439
Score = 203 bits (495), Expect = 6e-51
Identities = 119/337 (35%), Positives = 181/337 (53%), Gaps = 16/337 (4%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
+LL +L + FF ELI G + +S+AL+AD+FHMLSD+ + +I ++ ++ KK SK
Sbjct: 61 KLLFLLIVNLLFFLCELITGIVIHSLALLADAFHMLSDLLSQVIGLGAILLAKKKASKRL 120
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXX 128
T+G+ RAEV+GAL+N VFL+++ F I +EA++RFI+ E I PK
Sbjct: 121 TYGFVRAEVVGALINGVFLLSVAFFIIIEAIQRFIDIEEITQPKIMLIVAAVGLFINLAA 180
Query: 129 XXXXHVPPPSNVRHLTEIVNSNA---------DRALGHNSTDNEETDEMVKKAK--TQNH 177
H + H + ++ + H S + E + VK+ T+
Sbjct: 181 MLLFHDHHGHSHGHSHGHSHEHSHGHSHKHSHEGYQRHESHEEEMKENDVKEVAIDTETK 240
Query: 178 KSCKSSSDPGH--MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXX 235
K K + H +NMKGVFLHV+ DALGS++ V AL VW + +K+Y+DP
Sbjct: 241 KEDKKKKEHHHQNLNMKGVFLHVMGDALGSIVAVAVALCVWFIDGDWKYYLDPSLSVIVA 300
Query: 236 XXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIAS 295
PL+ IL+Q VP ++ + ++R + V GV ++HEFH+WQLA + IA+
Sbjct: 301 CVIICSGTPLVYSCVKILMQRVPQNVSIKKLKRDILAVNGVDSIHEFHLWQLANETNIAT 360
Query: 296 AHIRCR--NLSEYMKIAEKVKEFFHNEGIHSTTIQPE 330
H+ + M+I + VK FH G+HSTTIQ E
Sbjct: 361 IHLFLNEDDRCRVMEIVQDVKNVFHKYGVHSTTIQTE 397
>UniRef50_A1DD01 Cluster: Metal ion resistance protein/transporter
(Zrc1), putative; n=3; Pezizomycotina|Rep: Metal ion
resistance protein/transporter (Zrc1), putative -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 401
Score = 199 bits (485), Expect = 1e-49
Identities = 112/341 (32%), Positives = 184/341 (53%), Gaps = 12/341 (3%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKN 68
RL+ ++ ++ FF E+ VG+ T S+ALVAD+FH L+D+ I+A +++K+S + K K
Sbjct: 10 RLILVISISASFFLAEIAVGFYTRSLALVADAFHYLNDLVGFIVALVALKISQRSKHPKE 69
Query: 69 -TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXX 127
+FGW RA++LGA N VFL++L SI ++++ RF+ E I NPK
Sbjct: 70 LSFGWQRAQLLGAFFNGVFLLSLGISIFLQSIDRFVSLERIENPKLVLIIGCVGLALNLI 129
Query: 128 XXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEM---VKKAKTQNHKSCKSSS 184
H S+ D L + + E + V + ++ + KS +
Sbjct: 130 SGLFLHEHDHGETNTPDP---SDDDLELSTSLSRLERRSSLSARVLRPHLEHRHNVKSQA 186
Query: 185 DPGH-MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXW 243
GH + M GV +HVL DA +L V+ +ALV+W +++ ++Y DP
Sbjct: 187 KKGHDLGMMGVLIHVLGDAANNLGVIIAALVIWKAKYEGRYYADPAVSMAIAIVILLSSL 246
Query: 244 PLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN- 302
PL+R+S ILLQ+VP + + ++ L+ + GV +VHE H+W+L ++ +AS H+ +
Sbjct: 247 PLVRKSGTILLQSVPLGVDPEDVKHDLEAIPGVESVHELHIWRLNQEKALASVHLAVSDE 306
Query: 303 -LSEYMKIAEKVKEFFHNEGIHSTTIQPEFVEG-PQDENEV 341
++++M A+ + E FH GIHSTT+QPE V P D +
Sbjct: 307 LIADFMDKAKIINECFHAYGIHSTTLQPEHVRPIPSDSRSI 347
>UniRef50_A5DPS6 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 427
Score = 194 bits (473), Expect = 3e-48
Identities = 123/360 (34%), Positives = 184/360 (51%), Gaps = 33/360 (9%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
S K+ R+ +L L FF +E+IVGY S+AL+ADSFHML+D+ +LIIA +V++ K
Sbjct: 29 SSKEIRIGALLALDTVFFLLEVIVGYSVGSLALIADSFHMLNDIISLIIALWAVRVKNNK 88
Query: 65 WS--KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXX 122
+ + T+GW RAE+LGAL+NAVFL+ALCF+I +EA++RF+ I PK
Sbjct: 89 PADGRYTYGWQRAEILGALINAVFLLALCFTIIIEAIQRFVSPPEISLPKLVLGVGIAGL 148
Query: 123 XXXXXXXXXXHVPPPSNVRHLTEIVNSNADRALGH---NSTDNEETDEMVKKAKTQNHKS 179
H S+ + + + H + +E++ ++ N
Sbjct: 149 LSNILGLVLFHEHGHSHSHGSPGRDVESGEHSHSHGDEEAVSRQESEADLRSYFPDNVVR 208
Query: 180 CKSSSDP----GHMNM----------KGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHY 225
S S P H + +GVFLHVL DALG++ V+ +AL +W T + ++ Y
Sbjct: 209 HYSESTPLINEDHAKLHKKKKKSMNMEGVFLHVLGDALGNVGVIITALFIWKTNYSWRFY 268
Query: 226 IDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVW 285
DP PL R SS ILLQ PT + + + ++ ++ V ++H+FHVW
Sbjct: 269 SDPLVSLVITAIIFSSALPLCRRSSKILLQATPTDVNSNLVVEKIVSLPCVKSIHDFHVW 328
Query: 286 QLAGDRIIASAHI-----RCRNLSE---------YMKIAEKVKEFFHNEGIHSTTIQPEF 331
L D +IAS H+ NLS +++ +V+E H GIHS TIQPEF
Sbjct: 329 NLNEDILIASLHLELNDTETENLSNEEQQINKPAFVQAVAQVREILHAYGIHSATIQPEF 388
>UniRef50_Q5GR56 Cluster: Zinc transporter 1; n=1; Glomus
intraradices|Rep: Zinc transporter 1 - Glomus
intraradices
Length = 454
Score = 151 bits (365), Expect = 4e-35
Identities = 68/193 (35%), Positives = 116/193 (60%)
Query: 148 NSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLI 207
++N + ++ +D ++ + QNH+ +S ++NM+GVF+HVL DALG++
Sbjct: 199 SNNENISIKEEESDTNNNQKISETEDNQNHRDNQSHKKDKNLNMRGVFIHVLGDALGNIG 258
Query: 208 VVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQ 267
VV S L ++LT + ++ YIDP PL++ +S ILLQ VP+ + +D ++
Sbjct: 259 VVCSGLFIYLTHFSWRFYIDPLTSLILTIIILMSAIPLVKSASFILLQKVPSGLPIDDVR 318
Query: 268 RRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTI 327
R+K + GV++VHE H+WQL+ + I S HI + YM+IA +++ H G+HS TI
Sbjct: 319 SRIKELYGVLSVHELHIWQLSDTKRICSVHILLAPSANYMEIAADIRKILHVHGVHSITI 378
Query: 328 QPEFVEGPQDENE 340
QPE+V+ ++N+
Sbjct: 379 QPEYVKIGLNKND 391
Score = 110 bits (265), Expect = 5e-23
Identities = 49/107 (45%), Positives = 79/107 (73%), Gaps = 2/107 (1%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW- 65
++ R++ +L + FF E+I+GY NS+A++ADSFHML+D+ +L++A ++K++ +
Sbjct: 5 RQTRIIILLIIDISFFITEIILGYWINSLAIIADSFHMLNDIFSLVVALYALKLASRSTF 64
Query: 66 -SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
SK ++GW RAEVLGAL+N VFL+ALC SI ++A++RF + I NP
Sbjct: 65 SSKYSYGWQRAEVLGALINGVFLMALCLSIFIQAIERFFDPPDIKNP 111
>UniRef50_P20107 Cluster: Zinc/cadmium resistance protein; n=7;
Saccharomycetales|Rep: Zinc/cadmium resistance protein -
Saccharomyces cerevisiae (Baker's yeast)
Length = 442
Score = 148 bits (359), Expect = 2e-34
Identities = 76/185 (41%), Positives = 105/185 (56%), Gaps = 5/185 (2%)
Query: 159 STDNEETDEMVKKAKTQNHKSCKSSSDPGH--MNMKGVFLHVLSDALGSLIVVGSALVVW 216
S N ++E +H S PGH +NM GVFLHVL DALG++ V+ +AL +W
Sbjct: 198 SVVNRLSNESQPLLNHDDHDHSHESKKPGHRSLNMHGVFLHVLGDALGNIGVIAAALFIW 257
Query: 217 LTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGV 276
TE+ +++Y DP PL R +S ILLQ P+ I D IQR + V GV
Sbjct: 258 KTEYSWRYYSDPIVSLIITIIIFSSALPLSRRASRILLQATPSTISADQIQREILAVPGV 317
Query: 277 MAVHEFHVWQLAGDRIIASAHIR--CRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFVEG 334
+AVH+FHVW L IAS H++ C ++M A+ +++ FH GIHS T+QPEFV G
Sbjct: 318 IAVHDFHVWNLTESIYIASIHVQIDCAP-DKFMSSAKLIRKIFHQHGIHSATVQPEFVSG 376
Query: 335 PQDEN 339
+E+
Sbjct: 377 DVNED 381
Score = 122 bits (294), Expect = 1e-26
Identities = 54/110 (49%), Positives = 86/110 (78%), Gaps = 2/110 (1%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
+GK+ R++ +L L FF +E+ +GY+++S+AL+ADSFHML+D+ +L++A +V ++ +
Sbjct: 3 TGKELRIISLLTLDTVFFLLEITIGYMSHSLALIADSFHMLNDIISLLVALWAVDVAKNR 62
Query: 65 W--SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
+K T+GW RAE+LGAL+NAVFL+ALCFSI +EA++R IE + I NP+
Sbjct: 63 GPDAKYTYGWKRAEILGALINAVFLIALCFSIMIEALQRLIEPQEIQNPR 112
>UniRef50_A1D9L0 Cluster: Di-, tri-valent inorganic cation
transporter, putative; n=2; Trichocomaceae|Rep: Di-,
tri-valent inorganic cation transporter, putative -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 345
Score = 148 bits (358), Expect = 2e-34
Identities = 97/328 (29%), Positives = 165/328 (50%), Gaps = 17/328 (5%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
RL+ ++ ++ FF E+ +G T+S+ALVAD+FH L+D+ ++A L++K+S
Sbjct: 10 RLIMVIGISSCFFLTEISIGLYTHSLALVADAFHYLTDLIGFVVALLALKLSEIDDPPKI 69
Query: 69 -TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXX 127
FGW RA +LGA N L AL SI ++AV+RFI +HN
Sbjct: 70 LAFGWQRAPLLGAFFNGALLFALGISILLQAVERFIS---LHNSCSLLDALAWVSISSVL 126
Query: 128 XXXXXHVP-----PPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKS 182
+ +NV+ L E +S+A R STD+ + + ++ S
Sbjct: 127 LFFTAGLSFWMRSLVANVKALEE--SSHAHRHALDASTDSSIRTDDEGSIRLPPKRTGSS 184
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
D G M GV LHV+ DA+ +L V+ +ALV+W TE++ ++Y DP
Sbjct: 185 CRDVG---MLGVLLHVIGDAVNNLGVMIAALVIWFTEYEGRYYADPGASLWIAFIIILSS 241
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIA--SAHIRC 300
PLLR++ ILL P+ I ++ ++ L+ ++GV+++HE +VW ++ + +A +
Sbjct: 242 LPLLRKTGSILLGCAPSGIDLNDLRSDLEKIQGVLSIHEINVWHISQHKSLAVIGVLVTD 301
Query: 301 RNLSEYMKIAEKVKEFFHNEGIHSTTIQ 328
+++ + K+ V E GI S ++
Sbjct: 302 QHVPGFTKLTSMVNECCQKYGIQSVALR 329
>UniRef50_Q5KK51 Cluster: Di-, tri-valent inorganic cation
transporter, putative; n=3; Basidiomycota|Rep: Di-,
tri-valent inorganic cation transporter, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 523
Score = 142 bits (343), Expect = 2e-32
Identities = 68/183 (37%), Positives = 106/183 (57%), Gaps = 2/183 (1%)
Query: 149 SNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIV 208
S++ + L N++D E A+ H S G MNM+GVFLHV+ DALG++ V
Sbjct: 294 SDSGKKLAGNASDAESGHTHGSPAEHGRHGGHGHSH--GAMNMRGVFLHVVGDALGNVGV 351
Query: 209 VGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQR 268
+ + LV+W + ++ Y DP PL++ +S IL+Q VP+H+ +DA+++
Sbjct: 352 ISAGLVIWFCQGRWTLYFDPGVSLVITCIIFSSALPLVKSASYILMQGVPSHVSLDAVRQ 411
Query: 269 RLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQ 328
+ V GV +VHE H+WQL+ ++AS H+ +YM +A ++E H+ GIHS TIQ
Sbjct: 412 CIYEVPGVDSVHELHIWQLSESTVVASVHVMIEAGRDYMVVASGIRERMHSHGIHSVTIQ 471
Query: 329 PEF 331
PEF
Sbjct: 472 PEF 474
Score = 109 bits (261), Expect = 1e-22
Identities = 54/106 (50%), Positives = 74/106 (69%), Gaps = 3/106 (2%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM--SPKK 64
++ R++ +L + FF +ELI GY S+ALVADSFHML+DV +LI+A ++++ SP
Sbjct: 5 RQARIITLLVIDSVFFLIELITGYAVGSLALVADSFHMLNDVLSLIVALYTIRLATSPSS 64
Query: 65 WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
S N++GW RAE+LGAL+N VFLVALC SI +EAV R I N
Sbjct: 65 -SANSYGWQRAEILGALINGVFLVALCVSIGLEAVGRIFSPPEISN 109
>UniRef50_A7TP59 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 437
Score = 141 bits (342), Expect = 2e-32
Identities = 67/202 (33%), Positives = 110/202 (54%), Gaps = 1/202 (0%)
Query: 134 VPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKG 193
V P + V + + N + +N+ + +H + K+ + G +NM G
Sbjct: 173 VMPQNVVARESSYLLGNGTGSHNNNNHSDSHNHSHADSNHDHSHGNTKNQASHGSLNMHG 232
Query: 194 VFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLIL 253
VFLHVL DALG++ V+ +AL +W T++ +K+Y DP PL R++S IL
Sbjct: 233 VFLHVLGDALGNIGVIIAALFIWKTDYSWKYYTDPIVSLVITIIIFSSALPLSRKASKIL 292
Query: 254 LQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNL-SEYMKIAEK 312
LQ P+ I D++QR + + GV++VH+ H+W L IAS H++ + ++ +A+
Sbjct: 293 LQATPSTISADSVQRDILAIPGVISVHDLHIWNLTESVFIASVHVQVDSTPDKFTTVAKL 352
Query: 313 VKEFFHNEGIHSTTIQPEFVEG 334
+++ FHN IHS T+QPEF G
Sbjct: 353 IRDVFHNYNIHSATVQPEFASG 374
Score = 127 bits (307), Expect = 4e-28
Identities = 59/110 (53%), Positives = 88/110 (80%), Gaps = 2/110 (1%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
SGK+ R++ +L L FF +ELI+GY+++S+AL+ADSFHML+D+ +LI+A +V ++ +
Sbjct: 2 SGKEIRIVSLLILDTIFFLLELIIGYLSHSLALIADSFHMLNDIISLIVALWAVNVAKNR 61
Query: 65 W--SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
+K T+GW RAE+LGAL+NAVFL+ALCFSI +EA++R IE + I+NPK
Sbjct: 62 SPDAKYTYGWKRAEILGALINAVFLMALCFSILIEALQRLIEPQEINNPK 111
>UniRef50_Q6P3M0 Cluster: Solute carrier family 30 (Zinc
transporter), member 1; n=5; Euteleostomi|Rep: Solute
carrier family 30 (Zinc transporter), member 1 - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 498
Score = 137 bits (331), Expect = 5e-31
Identities = 59/108 (54%), Positives = 81/108 (75%)
Query: 225 YIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHV 284
Y+DP +PLL+ES+LILLQTVP I + + RL+++EGV+AVHE H+
Sbjct: 305 YLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDMHQLNARLRDLEGVLAVHELHI 364
Query: 285 WQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFV 332
WQLAG RIIA+AHI+C + + YM +A+++K+FFH+EGIH+TTIQPEFV
Sbjct: 365 WQLAGSRIIATAHIKCHDPTSYMDVAKRIKDFFHDEGIHATTIQPEFV 412
Score = 131 bits (316), Expect = 3e-29
Identities = 63/106 (59%), Positives = 83/106 (78%), Gaps = 2/106 (1%)
Query: 8 KCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS- 66
+ RLLCML LT GFF VE++V IT+S+A+++DSFHMLSDV AL++A ++V+ + + S
Sbjct: 7 RVRLLCMLSLTFGFFIVEVVVSRITSSLAMLSDSFHMLSDVIALVVALVAVRFAEQTQST 66
Query: 67 -KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
KNTFGW RAEV+GALVNAVFL ALCF+I +EA++RF E I P
Sbjct: 67 NKNTFGWIRAEVMGALVNAVFLTALCFTIILEAIERFTEPHEIEQP 112
Score = 43.6 bits (98), Expect = 0.008
Identities = 20/33 (60%), Positives = 28/33 (84%), Gaps = 1/33 (3%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWK 221
+NM+GVFLHVL DALGS+IVV +A ++++ WK
Sbjct: 231 LNMRGVFLHVLGDALGSVIVVINA-IIFVFVWK 262
>UniRef50_Q54T06 Cluster: Cation efflux family protein; n=1;
Dictyostelium discoideum AX4|Rep: Cation efflux family
protein - Dictyostelium discoideum AX4
Length = 573
Score = 134 bits (325), Expect = 2e-30
Identities = 67/163 (41%), Positives = 94/163 (57%), Gaps = 4/163 (2%)
Query: 170 KKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPX 229
KK K ++ +C +NM GVFLH L DA+ SL V+ + V+ T K+ YIDP
Sbjct: 360 KKKKKKSSGTCLGMD----LNMFGVFLHFLGDAISSLFVLITGAVIHFTHGKWTEYIDPA 415
Query: 230 XXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAG 289
PL++ S+ILLQ VP I +D+I+ ++ VEGV++ H+ HVWQL
Sbjct: 416 VSLIIVIMIAATSAPLVKRCSMILLQKVPDDIDLDSIRYKIAKVEGVVSQHDLHVWQLVD 475
Query: 290 DRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFV 332
IAS H+ E+ IA K+++ FH EGIHST+IQPEF+
Sbjct: 476 GMTIASVHVGIEQGREFQSIASKLRKIFHKEGIHSTSIQPEFL 518
Score = 71.7 bits (168), Expect = 3e-11
Identities = 39/92 (42%), Positives = 58/92 (63%), Gaps = 3/92 (3%)
Query: 17 LTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN--TFGWAR 74
LT + VEL S+ L++D FH LSDV +L+IA+ + K + K+ S N ++GWAR
Sbjct: 66 LTLLYVIVELGAALYVGSLTLLSDGFHNLSDVVSLVIAWWAQKAA-KRDSDNFMSYGWAR 124
Query: 75 AEVLGALVNAVFLVALCFSITVEAVKRFIEFE 106
AE+LG L N FL+++ + +EA+ RFI E
Sbjct: 125 AEILGGLTNGCFLLSMSLYVALEAIPRFIRPE 156
>UniRef50_A5ABY7 Cluster: Function: Zinc-replete cells accumulate
zinc in the vacuole via the Zrc1p precursor; n=2;
Ascomycota|Rep: Function: Zinc-replete cells accumulate
zinc in the vacuole via the Zrc1p precursor -
Aspergillus niger
Length = 431
Score = 134 bits (325), Expect = 2e-30
Identities = 67/191 (35%), Positives = 109/191 (57%), Gaps = 8/191 (4%)
Query: 159 STDNEETDEMVKKAKTQNHKSCKSSSDPGH-MNMKGVFLHVLSDALGSLIVVGSALVVWL 217
+T +E+ + A+ + K K GH +NM+GVFLHV+ DALG++ V+ SAL++WL
Sbjct: 189 TTSDEDLHKFHNHAQPKP-KDEKHGHGHGHDLNMRGVFLHVMGDALGNIGVIASALIIWL 247
Query: 218 TEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVM 277
T++ ++ Y+DP PL + +S ILLQ P + +D I+ ++ + GV+
Sbjct: 248 TDYSWRFYVDPGISLVITVIILLSAIPLCKAASRILLQAAPHGLSIDHIKEDIEGLPGVI 307
Query: 278 AVHEFHVWQLAGDRIIASAHIRC------RNLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
H HVWQL+ +++AS HI+ YM++A +V++ H GIHS+TIQPEF
Sbjct: 308 GSHHLHVWQLSDTKLVASIHIQVDTEIKGEGSERYMRLARQVRKCLHAYGIHSSTIQPEF 367
Query: 332 VEGPQDENEVS 342
E+ ++
Sbjct: 368 APDSDTEDTIA 378
Score = 113 bits (273), Expect = 5e-24
Identities = 55/108 (50%), Positives = 77/108 (71%), Gaps = 2/108 (1%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
K R+L +L + FF +ELI GY +S+ALVADSFHML+DV +L + +VK++ ++ +
Sbjct: 5 KTNRILILLAIDTAFFLLELIAGYSVHSLALVADSFHMLNDVLSLCVGLWAVKVANRETN 64
Query: 67 KN--TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
T+GW RAE LGALVN VFLVALC SI +EA++R +E + + NPK
Sbjct: 65 SKMYTYGWQRAETLGALVNGVFLVALCLSIFLEAIQRLVEPQEVKNPK 112
>UniRef50_Q5BCD5 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 500
Score = 134 bits (323), Expect = 4e-30
Identities = 73/202 (36%), Positives = 112/202 (55%), Gaps = 10/202 (4%)
Query: 150 NADRALGHNSTDNEETDEMVKKA-KTQNHKSCKSSSDP-GH-MNMKGVFLHVLSDALGSL 206
+ DRA + D+ K +T NH K GH +NM+GVFLHV+ DALG++
Sbjct: 256 HTDRAANYTDEHAPVRDQTKKDPHETHNHAQPKPKDKKHGHDLNMRGVFLHVMGDALGNI 315
Query: 207 IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAI 266
V+ SALV+WLT++ ++ Y+DP PL + +S ILLQ VP + +D I
Sbjct: 316 GVILSALVIWLTDYSWRFYVDPGISLVITVIILASAIPLCKAASRILLQAVPHGLSIDHI 375
Query: 267 QRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC------RNLSEYMKIAEKVKEFFHNE 320
+ ++++ GV H HVWQL+ + +AS HI+ YM +A++V++ H
Sbjct: 376 KEDIESLPGVKGSHHLHVWQLSDTKTVASIHIQVDTEIKGEGSERYMHLAKQVRQCLHAY 435
Query: 321 GIHSTTIQPEFV-EGPQDENEV 341
GI S+TIQPEF + ++N+V
Sbjct: 436 GIQSSTIQPEFPRDSDTEDNQV 457
Score = 111 bits (267), Expect = 3e-23
Identities = 54/108 (50%), Positives = 77/108 (71%), Gaps = 2/108 (1%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
K R++ +L + FF +ELI GY +S+ALVADSFHML+DV +L++ +VK++ ++ S
Sbjct: 5 KTNRIMILLVIDTAFFLLELIAGYSVHSLALVADSFHMLNDVISLLVGLWAVKVANRETS 64
Query: 67 KN--TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
T+GW RAE LGALVN VFLVAL SI +EA++R +E + + NPK
Sbjct: 65 SKMYTYGWQRAETLGALVNGVFLVALSLSIFLEAIQRLVEPQEVRNPK 112
>UniRef50_A1DI13 Cluster: Zinc/cadmium resistance protein; n=8;
Pezizomycotina|Rep: Zinc/cadmium resistance protein -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 534
Score = 134 bits (323), Expect = 4e-30
Identities = 63/160 (39%), Positives = 97/160 (60%), Gaps = 7/160 (4%)
Query: 187 GH-MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPL 245
GH +NM+GVFLHV+ DALG++ V+ SAL++WLT++ ++ Y+DP PL
Sbjct: 320 GHDLNMRGVFLHVMGDALGNIGVIVSALIIWLTDYSWRFYVDPGISLVITVIILASAIPL 379
Query: 246 LRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC----- 300
+ +S ILLQ VP + +D I+ ++ + GV+ H HVWQL+ +++AS HI+
Sbjct: 380 CKAASRILLQAVPAGLSIDHIKEDIERLPGVIGSHHLHVWQLSDTKLVASIHIQVDTEIK 439
Query: 301 -RNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFVEGPQDEN 339
YM++A +V++ H GIHS+TIQPEF E+
Sbjct: 440 GEGSERYMRLARQVRKCLHAYGIHSSTIQPEFAPDSDAED 479
Score = 113 bits (273), Expect = 5e-24
Identities = 55/108 (50%), Positives = 77/108 (71%), Gaps = 2/108 (1%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
K R+L +L + FF +ELI GY +S+ALVADSFHML+DV +L++ +VK++ ++
Sbjct: 5 KTNRILILLVIDTAFFLLELIAGYSVHSLALVADSFHMLNDVISLLVGLWAVKVANQETK 64
Query: 67 KN--TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
T+GW RAE LGALVN VFLVALC SI +EA++R +E + + NPK
Sbjct: 65 SKMYTYGWQRAETLGALVNGVFLVALCLSIFLEAIQRLVEPQEVKNPK 112
>UniRef50_UPI0000DB7A0C Cluster: PREDICTED: similar to CG5130-PA,
isoform A; n=2; Apocrita|Rep: PREDICTED: similar to
CG5130-PA, isoform A - Apis mellifera
Length = 511
Score = 130 bits (315), Expect = 4e-29
Identities = 84/271 (30%), Positives = 133/271 (49%), Gaps = 17/271 (6%)
Query: 67 KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI---HNPKXXXXXXXXXXX 123
KNTFGWAR +++ LV VFL + CFS+ VEA++ + + + H+P
Sbjct: 112 KNTFGWARIDIVTMLVCCVFLASFCFSLLVEAMQTLVHIDHLDEMHHPLPVLTIGACGIF 171
Query: 124 XXXX--XXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCK 181
+ V H+T N D L N ++++T E ++ +Q +S
Sbjct: 172 LNAFCYILIGGYTFNQGIVLHVT----MNGDVILRRN-VNSQQTKEGEQQLSSQTRRS-- 224
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
G +G+ DALG + V+ +++V+ T+ YIDP
Sbjct: 225 ---PLGIPKSQGL-RETCRDALGCVFVILVSILVYFTDSGVAKYIDPLFAIISSISLFAL 280
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNV-EGVMAVHEFHVWQLAGDRIIASAHIRC 300
+ ++ES LILLQT+P HI +D+++R L G++ VH+ H+WQL G +II++ HI
Sbjct: 281 SYSYMKESGLILLQTIPNHINIDSLKRELLEAFPGIVNVHDLHIWQLTGQKIISTVHIIF 340
Query: 301 RNLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
+ + Y I ++V FF GI TIQPEF
Sbjct: 341 LDPTVYTTITDQVTAFFREMGITQVTIQPEF 371
Score = 45.2 bits (102), Expect = 0.003
Identities = 18/55 (32%), Positives = 36/55 (65%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
+L +L T FF VE++ ++T+S+ L+ +++HML ++ AL+ S+K S ++
Sbjct: 14 QLYLVLFFTTAFFLVEIVASHVTHSLTLLLNAYHMLCNIIALVGCIASIKYSHRQ 68
>UniRef50_Q4SCU9 Cluster: Chromosome 14 SCAF14647, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 14 SCAF14647, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 448
Score = 130 bits (314), Expect = 5e-29
Identities = 63/107 (58%), Positives = 84/107 (78%), Gaps = 2/107 (1%)
Query: 8 KCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK--KW 65
+ RLLCML LT FF VE++V IT+S+++++DSFHMLSDV ALI+A ++V+ + K
Sbjct: 2 RARLLCMLTLTFVFFIVEVVVSRITSSLSMLSDSFHMLSDVIALIVALVAVRFAEKTHST 61
Query: 66 SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
SKNTFGW RAEV+GALVNAVFL ALCF+I +EA++RF E I +P+
Sbjct: 62 SKNTFGWIRAEVMGALVNAVFLTALCFTIVLEAIERFTEPHEIESPE 108
>UniRef50_A2R2G7 Cluster: Remark: the protein is probably
responsible for the uptake of zinc and cadmium ions;
n=2; Aspergillus|Rep: Remark: the protein is probably
responsible for the uptake of zinc and cadmium ions -
Aspergillus niger
Length = 408
Score = 130 bits (313), Expect = 7e-29
Identities = 86/276 (31%), Positives = 133/276 (48%), Gaps = 26/276 (9%)
Query: 61 SPKKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXX 120
SPK S FGW RA++LGA N V L AL I+VE NPK
Sbjct: 110 SPKALS---FGWQRAQLLGAFFNGVLLFAL--GISVE------------NPKLMFIMGAI 152
Query: 121 XXXXXXXXXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSC 180
H + H +S A L ++TD+ E +HK
Sbjct: 153 GLTLNLISATFLHEHHHHDHGHEP---SSGALEELPVSTTDDITGPERPGSPNHNDHKHL 209
Query: 181 KS---SSDPGH-MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXX 236
+ ++ GH + M GV +HV+ DA +L V+ +ALV+WL + ++Y DP
Sbjct: 210 SNGAHAASHGHDLGMLGVLIHVIGDAANNLGVMAAALVIWLAHYGGRYYADPGTSMGISI 269
Query: 237 XXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASA 296
PL+R +ILL++ P + ++ ++ L+ + GV++VHE H+W+L + +AS
Sbjct: 270 MIMLSSVPLVRRCGIILLESAPNGVDLEDVKHDLEKIPGVLSVHELHIWRLNQHKALASV 329
Query: 297 HIRCRNLS--EYMKIAEKVKEFFHNEGIHSTTIQPE 330
H+ + S ++K+++ + E FH GIHSTTIQPE
Sbjct: 330 HVMVSDCSVPSFLKLSKTINECFHAYGIHSTTIQPE 365
>UniRef50_Q9Y6M5 Cluster: Zinc transporter 1; n=25;
Euteleostomi|Rep: Zinc transporter 1 - Homo sapiens
(Human)
Length = 507
Score = 128 bits (310), Expect = 2e-28
Identities = 57/107 (53%), Positives = 75/107 (70%)
Query: 225 YIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHV 284
Y+DP +PLL+ES+LILLQTVP I + + + L+NVEGV VHE HV
Sbjct: 315 YLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIRNLIKELRNVEGVEEVHELHV 374
Query: 285 WQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
WQLAG RIIA+ HI+C + + YM++A+ +K+ FHN GIH+TTIQPEF
Sbjct: 375 WQLAGSRIIATVHIKCEDPTSYMEVAKTIKDVFHNHGIHATTIQPEF 421
Score = 121 bits (291), Expect = 3e-26
Identities = 57/113 (50%), Positives = 83/113 (73%), Gaps = 2/113 (1%)
Query: 1 MGRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM 60
MG + + RLLCML LT F +E++V +T+S+A+++DSFHMLSDV AL++A ++ +
Sbjct: 1 MGCWGRNRGRLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVALVAERF 60
Query: 61 SPKKWS--KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
+ + + KNTFGW RAEV+GALVNA+FL LCF+I +EA++RFIE + P
Sbjct: 61 ARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERFIEPHEMQQP 113
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/35 (65%), Positives = 29/35 (82%), Gaps = 1/35 (2%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWK 221
G +NM+GVFLHVL DALGS+IVV +ALV + + WK
Sbjct: 241 GQLNMRGVFLHVLGDALGSVIVVVNALVFYFS-WK 274
>UniRef50_Q2PIQ1 Cluster: Zn2+ transporter ZNT1 and related
Cd2+/Zn2+ transporters; n=1; Aspergillus oryzae|Rep:
Zn2+ transporter ZNT1 and related Cd2+/Zn2+ transporters
- Aspergillus oryzae
Length = 443
Score = 128 bits (309), Expect = 2e-28
Identities = 100/351 (28%), Positives = 167/351 (47%), Gaps = 50/351 (14%)
Query: 27 IVGYITNSMALVADSFHMLSDVAALIIAFLSVKM----SPKKWSKN---------TFGWA 73
IVG+ T+S+AL+AD+FH L+D+ I+A +++++ S ++ K +FGW
Sbjct: 52 IVGFYTHSLALIADAFHYLNDLIGFIVALVALRVGYLDSSQRLHKRLTDDAPKSLSFGWQ 111
Query: 74 RAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXXXXXH 133
RA++LGA N L AL S+ +++++RFI + + NPK H
Sbjct: 112 RAQLLGAFFNGALLFALGISVFLQSIERFISMQYVENPKLMFIMGAVGLGLNLISAIFLH 171
Query: 134 VPPPSNVRHLT-EIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDP---GH- 188
S +R + + + + + G S + E ++ NHK + P GH
Sbjct: 172 --GASGLRWAEHDHGHGHHEHSAGPLSPIPHSSYES-DISEHHNHKHQMHGTQPTSLGHD 228
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKH-YIDPXXXXXXXXXXXXXXWPL-- 245
+ M GV LHV+SDA +L V+ +ALV+WL ++ +H Y D L
Sbjct: 229 LGMLGVLLHVVSDAANNLGVMAAALVIWLAHYEGRHKYGDRHDDYAVFTSSRYLDLVLDC 288
Query: 246 ---------LRESSLILLQTVPTHIQVDAIQRRLKN---------------VEGVMAVHE 281
+R S LILL++ P + ++ L+ V GV+A+HE
Sbjct: 289 VVTQLRLCIVRRSGLILLESAPNGLDPADVKHDLEKARTNASGATSREAILVPGVLAIHE 348
Query: 282 FHVWQLAGDRIIASAHIRCR--NLSEYMKIAEKVKEFFHNEGIHSTTIQPE 330
H+W+L ++ +AS H+ +++ + K + + E FH GIHS T+QPE
Sbjct: 349 LHIWRLNQNKTLASVHVVVSDPSVTNFAKTTKTINECFHAYGIHSATLQPE 399
>UniRef50_UPI0000D55EC2 Cluster: PREDICTED: similar to CG5130-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG5130-PA, isoform A - Tribolium castaneum
Length = 473
Score = 124 bits (300), Expect = 3e-27
Identities = 77/271 (28%), Positives = 130/271 (47%), Gaps = 17/271 (6%)
Query: 67 KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI---HNPKXXXXXXXXXXX 123
KNTFGWAR +V+ L+ +F+ +L FS+ VEA++ + + + H+P
Sbjct: 123 KNTFGWARIDVISLLICCIFMASLSFSVFVEALQTLVHIDHLDEMHHPLSVLFIGAAGLL 182
Query: 124 XXXX--XXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCK 181
+ + ++TE + DR + ++VK+ + ++
Sbjct: 183 LNGVCYLLIGGYTFHQGSFLYVTESGDVVLDRVV---------VPDLVKQGGRRLSRT-- 231
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
+ P + FL + D +G + V+ AL+V+ T+ Y+DP
Sbjct: 232 RPTPPLPKRQRQGFLEMCRDVIGCVFVIICALIVYFTDKHIAKYVDPILSLVSAGSLLFL 291
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRL-KNVEGVMAVHEFHVWQLAGDRIIASAHIRC 300
+P ++ES LILLQT+P I +D +++ L + ++ VH+FHVWQL +II++ HI
Sbjct: 292 SYPHMKESCLILLQTIPDSINIDVLKKDLISHFPDIVNVHDFHVWQLTATKIISTVHIIF 351
Query: 301 RNLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
N Y I + +KEF + GI TIQPEF
Sbjct: 352 ENQKSYNTIMDDIKEFLIDNGITQVTIQPEF 382
Score = 46.8 bits (106), Expect = 9e-04
Identities = 22/55 (40%), Positives = 36/55 (65%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
+L +L LT FF ELI +IT+++ L+ DS+HML ++ AL +++K S +K
Sbjct: 23 QLYVILILTVMFFITELIFSHITHALTLLMDSYHMLCNILALTGCIITIKNSNRK 77
>UniRef50_UPI000155D410 Cluster: PREDICTED: similar to Eprs protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
Eprs protein - Ornithorhynchus anatinus
Length = 668
Score = 124 bits (298), Expect = 5e-27
Identities = 55/151 (36%), Positives = 93/151 (61%), Gaps = 6/151 (3%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEW------KYKHYIDPXXXXXXXXXXXXXX 242
+N++GV LHV+ DALGS++VV +A + ++ ++ YIDP
Sbjct: 420 LNIRGVLLHVMGDALGSVVVVIAATIFYVLPLDPSEPCNWECYIDPSLTILMVIIILSSA 479
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN 302
+PL++E++ ILLQ VP + V+ + +L V G+ ++H+ H+W+LA + IA+ H++C+
Sbjct: 480 FPLIKETATILLQMVPKGVNVEELTIQLSQVPGISSIHDVHIWELASGKTIATLHVKCQK 539
Query: 303 LSEYMKIAEKVKEFFHNEGIHSTTIQPEFVE 333
+Y K++E FHN GIHS TIQPE+++
Sbjct: 540 SRDYRDANFKMREIFHNAGIHSVTIQPEYLD 570
>UniRef50_A6SSD0 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 569
Score = 123 bits (297), Expect = 6e-27
Identities = 64/186 (34%), Positives = 100/186 (53%), Gaps = 12/186 (6%)
Query: 156 GHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGH----MNMKGVFLHVLSDALGSLIVVGS 211
GH+ ++ + + A N+KS K S GH M M + LHV+ DALG++ V+ +
Sbjct: 321 GHH--EHRSSRQSKHAAHNHNNKSKKKSGGHGHNHDDMGMNAMILHVIGDALGNVGVIVT 378
Query: 212 ALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLK 271
AL++WLT W + Y DP PL + ++ ILLQ P I V I+ ++
Sbjct: 379 ALIIWLTNWPGRLYADPAVSLFITIIILRSCIPLTKATAQILLQATPDSIDVALIKEDIE 438
Query: 272 NVEGVMAVHEFHVWQLAGDRIIASAHIRCR------NLSEYMKIAEKVKEFFHNEGIHST 325
N + V H H+WQL+ +++AS HI+ +YM++A++++E H GIHS
Sbjct: 439 NFDAVKGCHHVHIWQLSDSQLVASMHIQVAFPIGEDGGEKYMQLAKEIRECLHGHGIHSA 498
Query: 326 TIQPEF 331
T+QPEF
Sbjct: 499 TLQPEF 504
Score = 99.5 bits (237), Expect = 1e-19
Identities = 52/107 (48%), Positives = 71/107 (66%), Gaps = 1/107 (0%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
K R+L ML + FF VEL VG S+AL+AD+FHML+D+ +L + +VK + + +
Sbjct: 5 KSTRILVMLLIDAVFFIVELGVGLWVGSLALMADAFHMLNDIISLAVGLWAVKAARRNTT 64
Query: 67 -KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
K +FG+ RAE+LGA NAVFL+ALC SI +EAV RF + I PK
Sbjct: 65 DKYSFGFLRAEILGAFFNAVFLIALCVSIVLEAVGRFFDPPEIGEPK 111
>UniRef50_Q2H0R9 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 336
Score = 120 bits (289), Expect = 6e-26
Identities = 86/285 (30%), Positives = 134/285 (47%), Gaps = 25/285 (8%)
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXX 128
+FGW RA VLGA N FL+AL SI +++++RFI + I K
Sbjct: 19 SFGWQRARVLGAFFNGAFLLALGISILLQSIERFISLKEIEEVKLMLIMGCVGLGLNIIT 78
Query: 129 XXXXHVPPPSNVRHLTEIV-NSNADRALGHNS-TD----NEETDEMVKKAKTQ-----NH 177
H + H ++I+ + ++ + G S TD DE K NH
Sbjct: 79 AAFLH----EHHHHHSDIIPDPESETSPGAQSPTDLLHQGHAQDECPSKGPFPADDHANH 134
Query: 178 KSCKSSSDPG--HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEW--KYKHYIDPXXXXX 233
+ + + P + M G LHV DAL + V+ +A V+WL + + Y DP
Sbjct: 135 RHTQHTPHPPGRDLGMLGALLHVAGDALNNAGVIMAAAVMWLVPAAARGRFYADPAVGLA 194
Query: 234 XXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRII 293
PLLR S ILLQ+ P +++ ++ +++V GV++VHE H+W+L + I
Sbjct: 195 IALTVLATAVPLLRRSGEILLQSAPVGVRLGDVKADMESVPGVVSVHELHIWRLDQHKAI 254
Query: 294 ASAHIRC------RNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFV 332
ASAH+ +L+ + A ++E H GIHS T+QPE +
Sbjct: 255 ASAHVVVSGPGVGADLAGFAVQARIIRECLHAYGIHSVTLQPELL 299
>UniRef50_A7PMH0 Cluster: Chromosome chr14 scaffold_21, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr14 scaffold_21, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 521
Score = 119 bits (287), Expect = 1e-25
Identities = 95/335 (28%), Positives = 149/335 (44%), Gaps = 27/335 (8%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMS--PKK 64
K ++ L + G+ VE + G+++NS+ L++D+ HML D AAL I + +S P
Sbjct: 204 KSRKIALFLLINTGYMVVEFVSGFMSNSLGLISDACHMLFDCAALAIGLYASYISRLPAN 263
Query: 65 WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXX 124
S+ +G R EVL VNAVFLV + I +E+ +R +E + I
Sbjct: 264 -SQFNYGRGRFEVLSGYVNAVFLVLVGALIVLESFERILEPQEISTNSLLTVSIGGLLVN 322
Query: 125 XXXXXXXX---HVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCK 181
H + H +S++D L H+S D + K +H
Sbjct: 323 VVGLIFFHEEHHHAHGGSCSHSHSQSHSHSD--LHHHSHACGGHDHTKRNHKHIDH---- 376
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
NM+G+FLHVL+D +GS+ VV S L++ W+ DP
Sbjct: 377 --------NMEGIFLHVLADTMGSVGVVISTLLIKYKGWQVA---DPACSIFISVLIVAS 425
Query: 242 XWPLLRESSLILLQTVPT---HIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
PLLR S+ ILLQ VP H DA++ +K + GV + HVW ++ + H+
Sbjct: 426 VIPLLRNSAEILLQRVPRVHEHDLKDALKNVMK-IRGVCGIQNLHVWSFTNTDVVGTLHL 484
Query: 299 RCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFVE 333
++ +V H+ GI T+Q E+V+
Sbjct: 485 HISTEADKASTKVQVSNILHDAGIKDLTVQVEYVK 519
>UniRef50_A0S5V1 Cluster: Putative solute carrier family 30; n=1;
Hydra vulgaris|Rep: Putative solute carrier family 30 -
Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 201
Score = 119 bits (286), Expect = 1e-25
Identities = 77/200 (38%), Positives = 110/200 (55%), Gaps = 16/200 (8%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW--SKNTFGWARAEVL 78
FF VEL+VGY+T SMALVADSF MLSD ++I+ F++ S + S+ T+GW RAE+L
Sbjct: 3 FFIVELVVGYMTKSMALVADSFQMLSDTVSIIVGFVAFHCSKRSETSSRFTYGWVRAEIL 62
Query: 79 GALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK------XXXXXXXXXXXXXXXXXXXX 132
GALVN+VFL ALCF+I +E+ KR E + NPK
Sbjct: 63 GALVNSVFLAALCFTILIESFKRSAIPERVENPKLVLIVGAVGLLVNIIGLFLFNHHSNG 122
Query: 133 HVPPPSNVR--HLTEIV-NSNADRALGHNST----DNEETDEMVKKAKTQNHKSCKSSSD 185
H +V H E+V N A+ L +S D+++++ V + + N S K
Sbjct: 123 HSNNSESVEKGHNNEVVDNIVAEFPLVDSSEVVIYDSDKSNSQVPQVVSNNENS-KKKLG 181
Query: 186 PGHMNMKGVFLHVLSDALGS 205
+N++GV+L++L DALGS
Sbjct: 182 ASRLNIRGVYLNILGDALGS 201
>UniRef50_Q2HFW8 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 553
Score = 118 bits (285), Expect = 2e-25
Identities = 64/169 (37%), Positives = 96/169 (56%), Gaps = 11/169 (6%)
Query: 174 TQNH-KSCKSSSDPGH----MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDP 228
+ NH K KS GH M M + LHVL DALG++ V+ +ALV+WLT+W ++Y DP
Sbjct: 303 SHNHNKPKKSGKKHGHSHGDMGMNAMVLHVLGDALGNVGVIITALVIWLTDWPGRYYADP 362
Query: 229 XXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLA 288
PL +S ILLQ P HI ++ ++ ++ + GV++ H H+WQL+
Sbjct: 363 AVSLFITLIILRSCIPLTIAASKILLQATPEHIDLNDVREDIQALPGVISCHHVHIWQLS 422
Query: 289 GDRIIASAHIRCR-NLSE-----YMKIAEKVKEFFHNEGIHSTTIQPEF 331
+++AS HI+ +SE YM+++ ++ H GIHS TIQPEF
Sbjct: 423 DTKVVASMHIQVAFPISEAGGEKYMELSMMARKCLHAYGIHSATIQPEF 471
Score = 100 bits (240), Expect = 5e-20
Identities = 50/105 (47%), Positives = 73/105 (69%), Gaps = 1/105 (0%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
K R+ ML L FF +EL VG+ +S+AL+AD+FHML+D+ +L++ +V ++ K +
Sbjct: 5 KSTRIKVMLVLDTVFFLLELGVGFAVHSLALMADAFHMLNDIISLLVGLWAVSVASKATT 64
Query: 67 -KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
K ++GW RAE+LGA NAVFL+ALC SI +EA+ RFI+ I N
Sbjct: 65 DKFSYGWLRAEILGAFFNAVFLIALCVSIVLEALTRFIDPPEIGN 109
>UniRef50_Q0CAH3 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 365
Score = 118 bits (285), Expect = 2e-25
Identities = 61/196 (31%), Positives = 106/196 (54%), Gaps = 5/196 (2%)
Query: 152 DRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDP-GHMNMK--GVFLHVLSDALGSLIV 208
D+ GH + N K A +++ + ++ G+ ++ GVF+H++ D +L V
Sbjct: 132 DQESGHVTNTNSSVLSDGKHAHHKHYLNASATKPKKGNFDLALMGVFIHIMGDCANNLGV 191
Query: 209 VGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQR 268
+ + LV+WL ++ ++Y DP PL++ S LILLQ+ P ++ + ++
Sbjct: 192 IIAGLVIWLADYGGRYYADPAVSMAIAIMILFSSLPLIKRSGLILLQSAPDGVEHEDVKH 251
Query: 269 RLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLS--EYMKIAEKVKEFFHNEGIHSTT 326
L+ + G+ AVHE H+W+L + +ASAH+ N E+ K+A+ V E FH GIHS T
Sbjct: 252 DLEQIPGIRAVHELHIWRLNQKKSLASAHLVLENDDDLEFHKLAKTVNECFHAYGIHSVT 311
Query: 327 IQPEFVEGPQDENEVS 342
+QPE G + + V+
Sbjct: 312 LQPESRTGDKKDTSVT 327
Score = 81.4 bits (192), Expect = 3e-14
Identities = 37/99 (37%), Positives = 62/99 (62%), Gaps = 2/99 (2%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
RL ++ ++ FF E+ VG+ T S+ALVAD+FH LSD+ ++A ++ + K
Sbjct: 10 RLSAVIGISTSFFIAEIAVGFYTGSLALVADAFHYLSDIVGFVVALVAAIVEQKSSPPQA 69
Query: 69 -TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFE 106
TFGW R++++GA N V L L S+ +++++RFI+ E
Sbjct: 70 LTFGWQRSQLVGAFFNGVLLFGLGISVFLQSIERFIKLE 108
>UniRef50_Q9VPE3 Cluster: CG5130-PA, isoform A; n=5; Diptera|Rep:
CG5130-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 513
Score = 118 bits (284), Expect = 2e-25
Identities = 77/278 (27%), Positives = 135/278 (48%), Gaps = 14/278 (5%)
Query: 67 KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFE---VIHNP--KXXXXXXXXX 121
+NTFGWAR ++L L+ + L +L FS+ VEA++ + + +H P
Sbjct: 108 RNTFGWARIDILTMLIVFIILASLSFSLVVEALQTLVHIDHQDTMHLPIPVMMLGFIGLI 167
Query: 122 XXXXXXXXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCK 181
+ + HLT N +R + N D T +K++N + +
Sbjct: 168 LNGLTYLLIGGYTLHQGSFLHLTPGGNVVLERPMSSN-LDLSLTPMQRHLSKSRNDRQLR 226
Query: 182 SS--SDPGHM---NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYK--HYIDPXXXXXX 234
++ G + + + +L D ++ V+ A +V++ E + +IDP
Sbjct: 227 EELETEVGSVYFATKRQGAVEMLRDVSSTIFVIVCAAIVYVAEDEQHTAKFIDPVLSIFS 286
Query: 235 XXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRL-KNVEGVMAVHEFHVWQLAGDRII 293
+P ++ES LILLQT+P I ++ +R L +++ H+ H+WQLA R +
Sbjct: 287 CVLLVTLSYPYMKESCLILLQTIPGSIDLEIFERTLVTKFPEIISYHDLHIWQLAAHRYV 346
Query: 294 ASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
A+ HI+ +N Y+KI E+V+ +FH++GI + TIQPEF
Sbjct: 347 ATIHIQFQNPKLYLKIIEQVRSYFHDQGIGAVTIQPEF 384
>UniRef50_Q5ALP0 Cluster: Potential vacuolar cation transporter;
n=4; Saccharomycetales|Rep: Potential vacuolar cation
transporter - Candida albicans (Yeast)
Length = 479
Score = 118 bits (284), Expect = 2e-25
Identities = 55/110 (50%), Positives = 83/110 (75%), Gaps = 2/110 (1%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
+ K+ R++ +L L FF +E I+GY +S+AL+ADSFHML+D+ +LIIA +V++ K
Sbjct: 2 NSKEIRIVALLILDTVFFLLEAIIGYTVHSLALIADSFHMLNDIISLIIALWAVRVKNTK 61
Query: 65 WS--KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
+ K T+GW RAE+LGAL+NAVFL+ALCF+I +++++RF E + I NPK
Sbjct: 62 PADGKYTYGWQRAEILGALINAVFLLALCFTIIMDSIQRFFEPQEISNPK 111
Score = 100 bits (239), Expect = 7e-20
Identities = 56/156 (35%), Positives = 90/156 (57%), Gaps = 8/156 (5%)
Query: 144 TEIVNSNADRALGHNST-DNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDA 202
T +S+A+ + +N+T ++ T+ ++ Q K KS MNM+GVFLHVL DA
Sbjct: 230 TSANSSDANTVVNNNNTSEHSGTNNNTPQSALQKIKQ-KS------MNMEGVFLHVLGDA 282
Query: 203 LGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQ 262
LG++ V+ +ALV+W T++ ++ DP PL+R++S ILLQ+ P +I
Sbjct: 283 LGNIGVIITALVIWKTDYSWRFLADPITSLFITLIILNSALPLVRKASRILLQSAPPYID 342
Query: 263 VDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ I ++K + + +H+FHVW L D +IAS HI
Sbjct: 343 SNLIVNQIKQLPLIKNIHDFHVWNLNEDILIASLHI 378
>UniRef50_A4QRA6 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 532
Score = 118 bits (284), Expect = 2e-25
Identities = 63/188 (33%), Positives = 101/188 (53%), Gaps = 12/188 (6%)
Query: 156 GHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGH------MNMKGVFLHVLSDALGSLIVV 209
GH+++ + V ++K ++ GH M M+ + LHV+ DALG++ V+
Sbjct: 269 GHSNSHGRSRRDSVLHDHHNHNKPREAQKGGGHSHNHADMGMQAMILHVIGDALGNVGVI 328
Query: 210 GSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRR 269
+AL++W TEW + Y DP PL ++ ILLQ P HI + I+
Sbjct: 329 VTALIIWKTEWSGRFYADPAVSLFITCIILRSCIPLTLATAKILLQATPDHISIRDIKAD 388
Query: 270 LKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR-NLSE-----YMKIAEKVKEFFHNEGIH 323
++++ GV++ H H+WQL+ +++AS HI+ +SE YMK+A + + H GIH
Sbjct: 389 IQDLPGVVSCHHVHIWQLSDTKLVASMHIQVSFPISEEGGEKYMKLAMRARSCLHAYGIH 448
Query: 324 STTIQPEF 331
S TIQPEF
Sbjct: 449 SATIQPEF 456
Score = 105 bits (252), Expect = 2e-21
Identities = 52/107 (48%), Positives = 75/107 (70%), Gaps = 1/107 (0%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
K R+ ML + FFF+EL VG S+AL+AD+FHML+DV +L+I +V+++ K +
Sbjct: 5 KATRIGVMLAIDLAFFFLELGVGIYVGSLALMADAFHMLNDVISLVIGLWAVRVAQNKST 64
Query: 67 -KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
K ++GW RAE+LGA NAVFL+ALC SI +EA+ RF++ I NP+
Sbjct: 65 DKFSYGWLRAEILGAFFNAVFLIALCVSILLEALGRFVDPPTIQNPQ 111
>UniRef50_UPI00015A66AB Cluster: solute carrier family 30 (zinc
transporter), member 10; n=1; Danio rerio|Rep: solute
carrier family 30 (zinc transporter), member 10 - Danio
rerio
Length = 393
Score = 118 bits (283), Expect = 3e-25
Identities = 56/102 (54%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Query: 1 MGRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM 60
MGRYSGK CRL+ ML +T FF E++ GY+ NS+ALV+DSF+MLSD+ +L + + ++
Sbjct: 1 MGRYSGKTCRLILMLVITVIFFVAEIVAGYMGNSVALVSDSFNMLSDILSLCVGLTAARV 60
Query: 61 SPKKWS-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
S + S + +FG RAEV+GAL NAVFL+ALCFSI++E++KR
Sbjct: 61 SRRAGSGRFSFGLGRAEVVGALANAVFLIALCFSISMESLKR 102
Score = 59.7 bits (138), Expect = 1e-07
Identities = 26/85 (30%), Positives = 48/85 (56%), Gaps = 4/85 (4%)
Query: 259 THIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR----NLSEYMKIAEKVK 314
TH +++ + + + GV +VHE HVW+LA R +AS H++ + L + + +++
Sbjct: 290 THTELNTLMESVCRLPGVSSVHEAHVWELAKGRNVASLHVKLQAPAGALWAQVSLQQQIT 349
Query: 315 EFFHNEGIHSTTIQPEFVEGPQDEN 339
+ FH G+HS T+Q E + D +
Sbjct: 350 QIFHRAGVHSLTLQLELADSDADSS 374
>UniRef50_Q6XR72 Cluster: Solute carrier family 30 member 10; n=18;
Amniota|Rep: Solute carrier family 30 member 10 - Homo
sapiens (Human)
Length = 496
Score = 118 bits (283), Expect = 3e-25
Identities = 61/114 (53%), Positives = 79/114 (69%), Gaps = 2/114 (1%)
Query: 1 MGRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLS--V 58
MGRYSGK CRLL ML LT FF EL+ GY+ NS+AL++DSF+M SD+ +L + + +
Sbjct: 1 MGRYSGKTCRLLFMLVLTVAFFVAELVSGYLGNSIALLSDSFNMFSDLISLCVGLSAGYI 60
Query: 59 KMSPKKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
P + T+G+ARAEV+GAL NAVFL ALCF+I VEAV R E I +P+
Sbjct: 61 ARRPTRGFSATYGYARAEVVGALSNAVFLTALCFTIFVEAVLRLARPERIDDPE 114
Score = 116 bits (278), Expect = 1e-24
Identities = 63/184 (34%), Positives = 104/184 (56%), Gaps = 17/184 (9%)
Query: 156 GHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVV 215
G + E ++M+KK K KS + +N++GV LHV+ DALGS++VV +A++
Sbjct: 214 GDSFNTQNEPEDMMKKEK-------KSEA----LNIRGVLLHVMGDALGSVVVVITAIIF 262
Query: 216 WLTEWK------YKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRR 269
++ K ++ YIDP +PL++E++ ILLQ VP + ++ + +
Sbjct: 263 YVLPLKSEDPCNWQCYIDPSLTVLMVIIILSSAFPLIKETAAILLQMVPKGVNMEELMSK 322
Query: 270 LKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQP 329
L V G+ +VHE H+W+L +IIA+ HI+ Y + K++E FH+ GIH+ TIQ
Sbjct: 323 LSAVPGISSVHEVHIWELVSGKIIATLHIKYPKDRGYQDASTKIREIFHHAGIHNVTIQF 382
Query: 330 EFVE 333
E V+
Sbjct: 383 ENVD 386
>UniRef50_Q6UX54 Cluster: Solute carrier family 30 member 5; n=49;
Eumetazoa|Rep: Solute carrier family 30 member 5 - Homo
sapiens (Human)
Length = 765
Score = 117 bits (282), Expect = 4e-25
Identities = 80/324 (24%), Positives = 151/324 (46%), Gaps = 17/324 (5%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-N 68
++ LCL F FVEL G +TNS+ L++D FHML D +AL++ + MS K ++
Sbjct: 418 QIFYFLCLNLLFTFVELFYGVLTNSLGLISDGFHMLFDCSALVMGLFAALMSRWKATRIF 477
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXX 128
++G+ R E+L +N +FL+ + F + +E+V R I+ +
Sbjct: 478 SYGYGRIEILSGFINGLFLIVIAFFVFMESVARLIDPPELDTHMLTPVSVGGLIVNLIGI 537
Query: 129 XXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGH 188
H ++ A + H S+D+ + M + + S S+ +
Sbjct: 538 CAFSHAHSHAH----------GASQGSCH-SSDHSHSHHMHGHSDHGHGHSHGSAGGGMN 586
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
NM+GVFLHVL+D LGS+ V+ S +++ W DP PL+++
Sbjct: 587 ANMRGVFLHVLADTLGSIGVIVSTVLIEQFGW---FIADPLCSLSTAILIFLSVVPLIKD 643
Query: 249 SSLILLQTVPTHI--QVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEY 306
+ +LL +P ++ +++ +EG+++ + H W+ + + + HI+ +
Sbjct: 644 ACQVLLLRLPPEYEKELHIALEKIQKIEGLISYRDPHFWRHSASIVAGTIHIQVTSDVLE 703
Query: 307 MKIAEKVKEFFHNEGIHSTTIQPE 330
+I ++V + G+++ TIQ E
Sbjct: 704 QRIVQQVTGILKDAGVNNLTIQVE 727
>UniRef50_A3LTE1 Cluster: Zinc-and cadmium resistance protein; n=1;
Pichia stipitis|Rep: Zinc-and cadmium resistance protein
- Pichia stipitis (Yeast)
Length = 419
Score = 117 bits (282), Expect = 4e-25
Identities = 56/108 (51%), Positives = 80/108 (74%), Gaps = 2/108 (1%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
K+ R+ +L L FF +E I+GY +S+AL+ADSFHML+D+ +LIIA +V++ K +
Sbjct: 4 KEIRIAALLVLDTVFFLLEAIIGYSVHSLALIADSFHMLNDIISLIIALWAVRVKNTKPA 63
Query: 67 --KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
K T+GW RAE+LGAL+NAVFL+ALCF+I ++A++RF E VI PK
Sbjct: 64 DGKYTYGWQRAEILGALINAVFLLALCFTIVIDAIQRFFEPAVITQPK 111
Score = 97.1 bits (231), Expect = 6e-19
Identities = 50/125 (40%), Positives = 73/125 (58%), Gaps = 1/125 (0%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
MNM+GVFLHVL DALG++ V+ +AL +W T++ +++ DP PL R+
Sbjct: 229 MNMEGVFLHVLGDALGNIGVIITALFIWKTDYSWRYVSDPVTSLVITLIIFSSALPLCRK 288
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
SS ILLQ P +I + I + + V ++H+FHVW L D +IAS HI + S Y +
Sbjct: 289 SSKILLQATPPYINSNLIIEEIVKLPLVKSIHDFHVWNLNEDILIASLHIELED-SCYAQ 347
Query: 309 IAEKV 313
A +V
Sbjct: 348 QAPQV 352
Score = 37.5 bits (83), Expect = 0.52
Identities = 14/26 (53%), Positives = 19/26 (73%)
Query: 306 YMKIAEKVKEFFHNEGIHSTTIQPEF 331
++K+ +V+E H GIHS TIQPEF
Sbjct: 389 FLKVVSQVREVMHKFGIHSVTIQPEF 414
>UniRef50_O13918 Cluster: Zinc homeostasis factor 1; n=1;
Schizosaccharomyces pombe|Rep: Zinc homeostasis factor 1
- Schizosaccharomyces pombe (Fission yeast)
Length = 387
Score = 112 bits (270), Expect = 1e-23
Identities = 54/153 (35%), Positives = 88/153 (57%), Gaps = 6/153 (3%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++NM GVFLHVL DALG++ V+ +AL + T++ ++ DP PL +
Sbjct: 227 NLNMHGVFLHVLGDALGNIGVISAALFIKYTDYSWRFLFDPCISILLTFIILFSAIPLCK 286
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSE-- 305
++LILLQ P I++D + + +++GV +VHE H+WQL+ ++IA+ H+ C L +
Sbjct: 287 SAALILLQVAPQSIKLDDVSNLINHLDGVESVHELHIWQLSDVKLIATVHV-CVTLPDDK 345
Query: 306 ---YMKIAEKVKEFFHNEGIHSTTIQPEFVEGP 335
Y K+ ++ + GI+ TIQPEF P
Sbjct: 346 GESYTKLTTDIRNVLQSFGIYDVTIQPEFANHP 378
Score = 109 bits (261), Expect = 1e-22
Identities = 50/107 (46%), Positives = 76/107 (71%), Gaps = 2/107 (1%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM--SPKK 64
++ R++ +L + FFF+E+I GY +S+AL+ADSFHML+D+ +L++A + ++ S
Sbjct: 6 RQTRIILLLGIDVTFFFIEIITGYAIDSLALIADSFHMLNDIVSLLVALWATRLAHSTSH 65
Query: 65 WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
K T+GW RAE+LGAL N VFL+ALC I +EA++RFIE + NP
Sbjct: 66 EPKYTYGWQRAEILGALSNGVFLIALCMFIFMEAIERFIEPPSVSNP 112
>UniRef50_Q6DBM8 Cluster: Metal tolerance protein B; n=1;
Arabidopsis thaliana|Rep: Metal tolerance protein B -
Arabidopsis thaliana (Mouse-ear cress)
Length = 375
Score = 112 bits (270), Expect = 1e-23
Identities = 79/311 (25%), Positives = 146/311 (46%), Gaps = 12/311 (3%)
Query: 24 VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNTFGWARAEVLGALV 82
V+++ G+ NS+A++ D+ H+LSDVA L ++ L++K+S + + +N+FG+ R EVL A +
Sbjct: 71 VQIVGGFKANSLAVMTDAAHLLSDVAGLCVSLLAIKVSSWEANPRNSFGFKRLEVLAAFL 130
Query: 83 NAVFLVALCFSITVEAVKRFIE-FEVIHNPKXXXXXXXXXXXXXXXXXXXXHVPPPSNVR 141
+ + + I EA++R + ++ H +
Sbjct: 131 SVQLIWLVSGVIIHEAIQRLLSRSREVNGEIMFGISAFGFFMNLVMVLWLGHNHSHHHHD 190
Query: 142 HLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSD 201
H N H EE +E + K + KSSS ++N++G +LH ++D
Sbjct: 191 HHHHHHNHKHQHQHHHKEVVAEEEEEEMNPLKGE-----KSSSKEMNINIQGAYLHAMAD 245
Query: 202 ALGSLIVVGSALVVWLT-EWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTH 260
+ SL V+ ++W+ +W +D P+L+ IL++ VP
Sbjct: 246 MIQSLGVMIGGGIIWVKPKWVL---VDLICTLVFSAFALAATLPILKNIFGILMERVPRD 302
Query: 261 IQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNE 320
+ ++ ++R LK ++GV V++ HVW++ RI+ S HI + +I V+ F
Sbjct: 303 MDIEKLERGLKRIDGVKIVYDLHVWEITVGRIVLSCHILPEPGASPKEIITGVRNFCRKS 362
Query: 321 -GIHSTTIQPE 330
GI+ T+Q E
Sbjct: 363 YGIYHATVQVE 373
>UniRef50_Q29M69 Cluster: GA16530-PA; n=2; Endopterygota|Rep:
GA16530-PA - Drosophila pseudoobscura (Fruit fly)
Length = 716
Score = 112 bits (269), Expect = 2e-23
Identities = 80/331 (24%), Positives = 155/331 (46%), Gaps = 26/331 (7%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KW 65
+K + C+LCL+ F +E+I G ++NS+A+ D+ H+L+D+A +I+ ++ +S +
Sbjct: 370 RKLIVACVLCLS--FMILEVIGGVLSNSLAIATDAAHLLTDLAGFLISLFALYISARPNT 427
Query: 66 SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXX 125
+ FGW RAEV+GA+++ F+ + + A++R E +PK
Sbjct: 428 QRMNFGWYRAEVIGAMISVYFIWVITGILVWLAIQRLWVGEHNVDPKIMLITSAVAILFN 487
Query: 126 XXXXXXXHVP----PPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCK 181
H PS V T I+ H+ +E ++V+ + + H
Sbjct: 488 VIMAFQLHHGHGHFEPSEVVRQTRIL---------HDELPKKEL-QLVESSVSVVHVQPP 537
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLT-EWKYKHYIDPXXXXXXXXXXXX 240
+ +N++ +HV+ D + S+ V +AL+++ EW + +D
Sbjct: 538 KEN----INVRAAMIHVIGDMIQSVGVFVAALIIFFRPEWSF---VDAICTFLFSIIVVL 590
Query: 241 XXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC 300
+LR+ ++L++ P ++ D +QR ++EGV VH +W L+ +++ SAH+
Sbjct: 591 VTIRILRDVLMVLMEATPDYMDYDEVQRAFLSIEGVEHVHNLRIWALSINKVALSAHLAI 650
Query: 301 RNLSEYMKIAEKVKEFFHNE-GIHSTTIQPE 330
+ ++ I E+ + H TTIQ E
Sbjct: 651 KKDADPQSILEEATKMIHKRYRFFETTIQIE 681
>UniRef50_UPI000069F760 Cluster: solute carrier family 30 (zinc
transporter), member 10; n=1; Xenopus tropicalis|Rep:
solute carrier family 30 (zinc transporter), member 10 -
Xenopus tropicalis
Length = 385
Score = 111 bits (267), Expect = 3e-23
Identities = 53/147 (36%), Positives = 89/147 (60%), Gaps = 6/147 (4%)
Query: 191 MKGVFLHVLSDALGSLIVVGSALVVWL------TEWKYKHYIDPXXXXXXXXXXXXXXWP 244
+ GV LHV+ DALGS++VV +A++ ++ ++ YIDP +P
Sbjct: 214 LAGVMLHVVGDALGSVVVVVTAVIFYVLPLDANAPCNWQCYIDPSLTVVMVAIILYSAFP 273
Query: 245 LLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLS 304
L++E++ ILLQ VP +QV I ++L V GV +VHE H+W+LA + IA+ H++ ++ +
Sbjct: 274 LIKETAYILLQMVPQGVQVGEIGQKLALVPGVNSVHEIHIWELASGKNIATLHVKFQDFA 333
Query: 305 EYMKIAEKVKEFFHNEGIHSTTIQPEF 331
+ +++++ FH E IH+ TIQ EF
Sbjct: 334 SHATASQEIRRIFHEEEIHAVTIQAEF 360
Score = 108 bits (260), Expect = 2e-22
Identities = 54/110 (49%), Positives = 79/110 (71%), Gaps = 2/110 (1%)
Query: 3 RYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP 62
RY+GK CRL+ ML LT FF EL+ GY+ NS+AL++DSF+MLSD+ +L + + ++S
Sbjct: 1 RYTGKTCRLIFMLVLTVIFFVAELVSGYLGNSIALISDSFNMLSDLISLCVGITASQISR 60
Query: 63 KK--WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
+K + T+G+ RAEV+GAL NA+FL ALCF+I V++V R + + I N
Sbjct: 61 RKSRGPRATYGYPRAEVVGALCNAIFLTALCFTILVDSVLRLAQPQRIDN 110
>UniRef50_Q8TCH2 Cluster: Zinc transporter-like 2 protein; n=37;
Eumetazoa|Rep: Zinc transporter-like 2 protein - Homo
sapiens (Human)
Length = 376
Score = 111 bits (267), Expect = 3e-23
Identities = 93/344 (27%), Positives = 148/344 (43%), Gaps = 31/344 (9%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-- 68
L LCL F FVEL+ G +N + L++DSFHM D A++ + +S KW N
Sbjct: 38 LFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVIS--KWGDNDA 95
Query: 69 -TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXX 127
++G+ RAEVL VN +FL+ F I E V+R + +H+ +
Sbjct: 96 FSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIG 155
Query: 128 XXXXXH----VPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNH------ 177
H S H + N D+A GH D+ + E VK +H
Sbjct: 156 IFVFKHGGHGHSHGSGHGHSHSLFNGALDQAHGH--VDHCHSHE-VKHGAAHSHDHAHGH 212
Query: 178 --------KSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPX 229
S K ++ P ++GVFLH+L+D LGS+ V+ SA+++ + DP
Sbjct: 213 GHFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMM---QNFGLMIADPI 269
Query: 230 XXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQ--RRLKNVEGVMAVHEFHVWQL 287
PLLRES IL+Q P ++ Q +R++ ++G ++ E H W L
Sbjct: 270 CSILIAILIVVSVIPLLRESVGILMQRTPPLLENSLPQCYQRVQQLQGAYSLQEQHFWTL 329
Query: 288 AGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
D + + + ++ I + F G+ +Q +F
Sbjct: 330 CSDVYVGTLKLIVAPDADARWILSQTHNIFTQAGVRQLYVQIDF 373
>UniRef50_Q95QW4 Cluster: Cation diffusion facilitator family
protein 1; n=3; Caenorhabditis|Rep: Cation diffusion
facilitator family protein 1 - Caenorhabditis elegans
Length = 561
Score = 108 bits (259), Expect = 2e-22
Identities = 54/145 (37%), Positives = 86/145 (59%), Gaps = 1/145 (0%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSA-LVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
++N+ GV+LH+LSDA GS+IV+ SA V +L WK Y+DP L+
Sbjct: 382 NVNIHGVWLHLLSDAFGSVIVMISAGFVYFLPTWKIAAYLDPILSISLASIMGFTAVVLV 441
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEY 306
+ S LL+ P + ++ +++ L ++ GV V + VW L G RIIA+AH+ + + +
Sbjct: 442 KTSGEKLLKQTPEGLDLEKVKKDLCSIVGVSKVEKLSVWTLCGQRIIAAAHVNICHPAVF 501
Query: 307 MKIAEKVKEFFHNEGIHSTTIQPEF 331
+ A K+K +FH+ G+HSTTI+P F
Sbjct: 502 PEAAYKIKNYFHDLGVHSTTIEPTF 526
Score = 83.8 bits (198), Expect = 6e-15
Identities = 38/101 (37%), Positives = 63/101 (62%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNTF 70
L+ + +T F +E I G + +S+A++ADS+HM +DV ALI+AF +K++ + ++ +
Sbjct: 113 LIIQIGMTVIFCALEFITGVVCSSIAMLADSYHMAADVMALIVAFTCIKIATRPSTRLGY 172
Query: 71 GWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
GW RAE LG N +F+ +C + EAV R I +I +P
Sbjct: 173 GWVRAETLGGFFNGIFMCTVCVLVFQEAVGRIINVHMITHP 213
>UniRef50_Q7PWD5 Cluster: ENSANGP00000006521; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000006521 - Anopheles gambiae
str. PEST
Length = 422
Score = 106 bits (255), Expect = 8e-22
Identities = 84/342 (24%), Positives = 156/342 (45%), Gaps = 20/342 (5%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
KK L MLC+ F E+I G +NS+A+ D+ H+++D+A+ +I+ ++ ++ + +
Sbjct: 93 KKLMLASMLCII--FMIAEIIGGIYSNSLAIATDAAHLMADLASFMISLFALWIAARPST 150
Query: 67 KN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI--EFEVIHNPKXXXXXXXXXXX 123
K +FGW RAEV+GAL++ + + + + AV R I +FE+
Sbjct: 151 KRLSFGWYRAEVIGALLSVLMIWVVTAILFYLAVLRTINKDFELNGEVMLVTSGLGILVN 210
Query: 124 XXXXXXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSS 183
H +++ H T I+ + R G +H
Sbjct: 211 IIAAVRVGFHKHTHTHM-HSTLIMPLFSSRLFGSMGATLHHHGH--------SHGGGGGH 261
Query: 184 SDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLT-EWKYKHYIDPXXXXXXXXXXXXXX 242
+ ++N++ F+HVLSD + SL V +ALV++ EW + IDP
Sbjct: 262 HEEQNINVRAAFVHVLSDFVQSLGVFIAALVIYFKPEW---NIIDPICTFLFSVLVLGTT 318
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN 302
++R++ ++L++ P ++ + + +EGV+ VH +W L+ ++I +AH+
Sbjct: 319 LAIMRDAIVVLMEGTPKYLDYTEVMQTFLQIEGVVRVHNLRIWALSINKIALAAHLAVEP 378
Query: 303 LSEYMKIAEKVKEFFHNE-GIHSTTIQPE-FVEGPQDENEVS 342
+ + K E H + TT+Q E F +D N+ S
Sbjct: 379 STNTELVLNKATETVHAKYQFFETTLQIEVFQPDMEDCNQCS 420
>UniRef50_UPI00003C04C2 Cluster: PREDICTED: similar to CG6672-PA;
n=2; Endopterygota|Rep: PREDICTED: similar to CG6672-PA
- Apis mellifera
Length = 352
Score = 105 bits (253), Expect = 1e-21
Identities = 88/337 (26%), Positives = 139/337 (41%), Gaps = 24/337 (7%)
Query: 4 YSGKKCR-LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP 62
+S K R L L L F +EL+ G TNS+ L++DSFHM D L+ + ++
Sbjct: 28 FSDKNTRNLFLFLLLNLSFACIELMYGIWTNSLGLISDSFHMFFDCTGLLFGLAASVIT- 86
Query: 63 KKWSKN---TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXX 119
KW N ++G+ RAEVLG VNA+ L + I EAV+R IE I + +
Sbjct: 87 -KWRANERYSYGYVRAEVLGGFVNALLLFFIALFIMSEAVERAIEPPEIKHERLLVVSIM 145
Query: 120 XXXXXXXXXXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKS 179
H S+ H+ + T + + + +H
Sbjct: 146 GLIVNLVGMYVFRHGHGHSH----------GMGHGHSHSHSHGSHTQSHLNHSHSHDHHD 195
Query: 180 CK---SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXX 236
+ S S MKGVFLH+L+D LGS+ V+ SA+++ L W DP
Sbjct: 196 IEIDPSFSGTNSQIMKGVFLHILADTLGSVGVIISAVLMRLFGW---FIADPICSMLISV 252
Query: 237 XXXXXXWPLLRESSLILLQTVPTHIQ--VDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIA 294
L+++S IL+Q P + + ++ + GV +V E H W L D +
Sbjct: 253 LIVLSVLSLMKDSWEILMQRQPAALDHILPQCYNKVTQLAGVYSVQEPHFWTLCSDVYVG 312
Query: 295 SAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
+ E + + F G+ T+Q ++
Sbjct: 313 CLKLEVARTVEPKYVVAHTQMIFQAAGVRHLTVQLDY 349
>UniRef50_A2FW10 Cluster: Cation efflux family protein; n=4;
Trichomonas vaginalis G3|Rep: Cation efflux family
protein - Trichomonas vaginalis G3
Length = 438
Score = 104 bits (249), Expect = 4e-21
Identities = 55/153 (35%), Positives = 83/153 (54%), Gaps = 1/153 (0%)
Query: 190 NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRES 249
N+KGVFLH+ D LGS+ V SA V T+W+ + Y+DP LLR +
Sbjct: 201 NLKGVFLHITGDFLGSVAVCISACVCLWTKWEGRFYLDPACSILIFCILIYGSQNLLRRT 260
Query: 250 SLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKI 309
+LL+T P + V++++ L +EG++AVHE HVW+L +R +A HI + K+
Sbjct: 261 GSVLLETCPPGVDVNSMKIDLMKIEGMVAVHELHVWELCKERYLALLHIVVDSKDRNKKV 320
Query: 310 AEKVKEFFHNEGIHSTTIQPEFVEG-PQDENEV 341
E+ I STT+Q EFV+ PQ + +
Sbjct: 321 LEQTHNVMIAHKIFSTTVQIEFVDDFPQGTDHI 353
Score = 101 bits (241), Expect = 4e-20
Identities = 50/107 (46%), Positives = 72/107 (67%), Gaps = 1/107 (0%)
Query: 6 GKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLS-VKMSPKK 64
G RL+ M+ LTG FF ELI G++T S++L +D++HMLSD A+L+I ++ K
Sbjct: 66 GVTWRLITMIVLTGVFFLAELITGFVTKSLSLQSDAWHMLSDEASLVIGLIAHEKAKRPP 125
Query: 65 WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
K TFG AR+EV+G N+VFL+A+C +I EA++RFI+ E I P
Sbjct: 126 TDKYTFGLARSEVIGGFTNSVFLLAVCLTILFEAIERFIKVEEIVEP 172
>UniRef50_Q4T2T2 Cluster: Chromosome undetermined SCAF10190, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF10190, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 317
Score = 103 bits (248), Expect = 5e-21
Identities = 74/307 (24%), Positives = 142/307 (46%), Gaps = 12/307 (3%)
Query: 29 GYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLGALVNAVFL 87
GY S+A++ D+ H+L D + II+ LS+ +S + + +GW RAE+LGAL++ +
Sbjct: 2 GYFAGSLAVMTDAAHLLVDFLSFIISLLSLWLSSRPATHRLNYGWHRAEILGALLSVFTI 61
Query: 88 VALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXXXXXHVPPPSNVRHLTEIV 147
+ + AV+R I + K H S H +
Sbjct: 62 WVVTAVLVYLAVERLINNDYTIEGKIMLITSGCAVLANIIMALTLH---QSGHGHSHGGL 118
Query: 148 NSNAD-RALGHNSTD--NEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALG 204
SN A H+ T+ N+ + +V + +++K ++ + +++ F+HV+ D L
Sbjct: 119 GSNGHGHAHSHDKTEKSNQNCNGVVDPEQNRDNKGHRTQQ--ANASVRAAFVHVVGDLLQ 176
Query: 205 SLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVD 264
S+ V+ SA+++++ +YK DP ++R+ ++L++ P ++
Sbjct: 177 SISVLISAIIIFVKP-EYK-IADPICTFLFSIFVLFTTVTIIRDIVIVLMEGAPVGVKYS 234
Query: 265 AIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC-RNLSEYMKIAEKVKEFFHNEGIH 323
++ L V+GV AVH H+W L ++ + +AH+ + + E + F + H
Sbjct: 235 DVRDGLLAVKGVRAVHNLHIWALTMNQAVLTAHVAIDETVDAQSVLREMTQACFSSYNFH 294
Query: 324 STTIQPE 330
S TIQ E
Sbjct: 295 SVTIQME 301
>UniRef50_Q7QZ17 Cluster: GLP_464_49476_50732; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_464_49476_50732 - Giardia lamblia
ATCC 50803
Length = 418
Score = 103 bits (247), Expect = 7e-21
Identities = 55/182 (30%), Positives = 92/182 (50%), Gaps = 7/182 (3%)
Query: 163 EETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKY 222
E T ++ A+ + + + ++ M GVFLHVL D +GS++ + SALV
Sbjct: 210 ESTTLLLNGAQKRRRRGHRGPKKQRNITMHGVFLHVLGDLMGSVVAIVSALVQKFVTHPL 269
Query: 223 KHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEF 282
H +DP PLL+ + ILLQ +P + +D ++ R+ +V+GV+ VH+
Sbjct: 270 AHLVDPMTTMLMVIIIVCAAVPLLKSTIRILLQAIPEGLSLDVLKERVLDVDGVLGVHDL 329
Query: 283 HVWQLAGDRIIASAHIRCRNLS------EYMKIAEKVKEFFHNEGIHSTTIQPEFVEGPQ 336
HVW + +I H+ N S + +I + VK FH+ +H+ TI+ E+V P
Sbjct: 330 HVWTFTDETVIGHCHVVVCNPSGAIDRTRHCQIMKDVKSVFHSLEVHNITIEIEYV-SPD 388
Query: 337 DE 338
+E
Sbjct: 389 EE 390
Score = 83.0 bits (196), Expect = 1e-14
Identities = 41/98 (41%), Positives = 63/98 (64%), Gaps = 1/98 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KN 68
RL+ ML + + ELIVG + NS+ LV D+FHMLSD+ +L+I +S+ + K+ S +
Sbjct: 27 RLIAMLVMVFFYMLAELIVGIVGNSLTLVGDAFHMLSDLLSLVIGLISLVLGRKQASAQA 86
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFE 106
TFG+ R+E +G NA FL++ F + EAV++ I E
Sbjct: 87 TFGYKRSETIGGFFNASFLLSTAFFLVTEAVQKLITAE 124
>UniRef50_Q2UAQ9 Cluster: Zn2+ transporter ZNT1 and related
Cd2+/Zn2+ transporters; n=1; Aspergillus oryzae|Rep:
Zn2+ transporter ZNT1 and related Cd2+/Zn2+ transporters
- Aspergillus oryzae
Length = 413
Score = 102 bits (244), Expect = 2e-20
Identities = 67/211 (31%), Positives = 103/211 (48%), Gaps = 10/211 (4%)
Query: 28 VGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN--TFGWARAEVLGALVNAV 85
VG+ T S+ALVAD+FH L+D+ I+AF +VK+S KK S +FGW RA +LGA N V
Sbjct: 16 VGFYTKSLALVADAFHYLNDIIGFIVAFAAVKISSKKESPKDLSFGWQRARLLGAFFNGV 75
Query: 86 FLVALCFSITVEAVKRFIE------FEVIHNPKXXXXXXXXXXXXXXXXXXXXHVP-PPS 138
FL+AL SI +++++RFI + + H P
Sbjct: 76 FLLALGVSIFLQSIERFISPQAGSYYWLCWAGAEYTKRVIPSRFFLDSEHDHSHDNLPGG 135
Query: 139 NVRHLTEI-VNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLH 197
N+ E +N + A + E + H + ++ + + GVF+H
Sbjct: 136 NLDASAESGINEVTELANREDRKSAEHPRQAYAFHTGHRHNNLQAQKKGYDLGLLGVFIH 195
Query: 198 VLSDALGSLIVVGSALVVWLTEWKYKHYIDP 228
VL DA ++ V+ SAL++WLT ++Y DP
Sbjct: 196 VLGDAFNNVGVIISALIIWLTHSASRYYADP 226
Score = 62.5 bits (145), Expect = 2e-08
Identities = 26/67 (38%), Positives = 44/67 (65%), Gaps = 2/67 (2%)
Query: 276 VMAVHEFHVWQLAGDRIIASAHIRCRNL--SEYMKIAEKVKEFFHNEGIHSTTIQPEFVE 333
V ++HE H W+L ++ +AS H+ ++ SE++K+A+ + E FH+ GIHS +QPE V+
Sbjct: 323 VSSIHELHAWRLNQEKALASVHVGLPDIRISEFVKLAKTMNECFHSYGIHSAIVQPELVQ 382
Query: 334 GPQDENE 340
+D E
Sbjct: 383 TVEDTTE 389
>UniRef50_A0E0R2 Cluster: Chromosome undetermined scaffold_72, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_72,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 574
Score = 101 bits (243), Expect = 2e-20
Identities = 90/298 (30%), Positives = 136/298 (45%), Gaps = 33/298 (11%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
+L+ L L F FVELI G+I+NS+ L+ DS HML D +AL IA + M+ +K +
Sbjct: 280 KLMIQLSLNFSFMFVELIYGWISNSLGLITDSLHMLIDSSALAIALFASFMAKRKANSTY 339
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXX 128
TFG+ R E+L N VF L F++ VE + FE + P+
Sbjct: 340 TFGFERVEILSGYANGVF---LLFAV-VEIISE--SFERVITPQEVLPEKMLIVSFLGLL 393
Query: 129 XXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGH 188
NV L N H +EE DE +++ ++H C D H
Sbjct: 394 V---------NVIGLFFFHN--------HGHIHSEEVDEQLEE---KHHHHCSHHHDHNH 433
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
N+ GV+LH+L+DALGS+ + SAL+++ ++ H DP LL++
Sbjct: 434 -NLSGVYLHILADALGSVACIISALLIYYYQF---HMADPIASIIISLLILTTTITLLKD 489
Query: 249 SSLILLQTVP-THIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSE 305
+S ILL VP + +V A N G E +WQ ++I +A + + E
Sbjct: 490 TSKILLMHVPYSGKKVLAAISHDFNHRG-FEPQEMKLWQYKEKKLIFTARFQIKQSDE 546
>UniRef50_UPI0000F1F0D2 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 320
Score = 100 bits (240), Expect = 5e-20
Identities = 71/305 (23%), Positives = 135/305 (44%), Gaps = 13/305 (4%)
Query: 29 GYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLGALVNAVFL 87
GY S+A++ D+ H+L D+ + II+ S+ +S + ++ +GW RAE+LGAL++ +F
Sbjct: 9 GYFAGSLAVMTDAAHLLVDLTSFIISLCSLWLSSRPATRTLNYGWHRAEILGALLS-IFT 67
Query: 88 VALCFSITVE-AVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXXXXXHVPPPSNVRHLTEI 146
+ L + V AV+R I H S H
Sbjct: 68 IWLVTGVLVYLAVERIINDNFTIEGTVMLITSGCAVLANIIMALTLH---QSGHGHS--- 121
Query: 147 VNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSL 206
+ GH+ +E + + + + +++ F+HV+ D L S+
Sbjct: 122 -HGGLSAGHGHSHDHGKENGHSHSDGSHHDVEEQRPGKTQANASVRAAFVHVIGDLLQSI 180
Query: 207 IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAI 266
V+ SAL+++ +YK DP + ++R+ ++L++ P + + +
Sbjct: 181 SVLVSALIIFFKP-EYK-IADPICTFLFSLFVLGTTFTIMRDIVIVLMEGTPAGVNYNEV 238
Query: 267 QRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEF-FHNEGIHST 325
++ L V+GV AVH H+W L ++ + SAH+ + ++ ++ + F HS
Sbjct: 239 RQLLLGVKGVKAVHNLHIWALTMNQAVLSAHVATDETVDPQEVLREMTQVCFTKYSFHSV 298
Query: 326 TIQPE 330
TIQ E
Sbjct: 299 TIQLE 303
>UniRef50_UPI0000DD7936 Cluster: PREDICTED: similar to solute
carrier family 30 (zinc transporter), member 10 isoform
a; n=5; Mammalia|Rep: PREDICTED: similar to solute
carrier family 30 (zinc transporter), member 10 isoform
a - Homo sapiens
Length = 152
Score = 99 bits (238), Expect = 9e-20
Identities = 49/112 (43%), Positives = 75/112 (66%), Gaps = 1/112 (0%)
Query: 1 MGRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM 60
MGRYSG+ RL+ M ++ F +EL++ Y+ NS++L +D+F +LS ++II F V+
Sbjct: 1 MGRYSGRSFRLILMCVVSILLFVMELVIAYVGNSLSLASDAFAVLSHFVSMIIGFFGVRA 60
Query: 61 SP-KKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
S K+ K+T+G+ RA+V+GA N +F VAL FSI VEA+KR+I + P
Sbjct: 61 SNIKQHKKSTYGFLRADVVGAFGNTIFAVALMFSILVEAIKRYINPQKTEEP 112
>UniRef50_Q54QU8 Cluster: Putative uncharacterized protein; n=2;
cellular organisms|Rep: Putative uncharacterized protein
- Dictyostelium discoideum AX4
Length = 543
Score = 99 bits (238), Expect = 9e-20
Identities = 84/338 (24%), Positives = 146/338 (43%), Gaps = 19/338 (5%)
Query: 5 SGKKCR--LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP 62
S KK R L+ L LT F E++ GY NS+A++ D+ H+L+D+ A+ ++ ++ +S
Sbjct: 179 SKKKARYSLILALTLTTIFMVGEIVGGYFANSLAIMTDAAHLLTDIGAMFLSLFAMWISQ 238
Query: 63 -KKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXX 121
S +FG+ RAE+LGALV+ + + AL + EA++R + + K
Sbjct: 239 HPPTSSMSFGFHRAEILGALVSVLMIWALTGVLVYEAIQRILYPPDAVDGKIMFIIASCG 298
Query: 122 XXXXXXXXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCK 181
H S + +G + + + + Q+ +
Sbjct: 299 LFINIIDAIILHW--GSGGHGHSHGGGHGHSHGIGGGTQKKKSKKNRLLNNQGQDIEDLG 356
Query: 182 SSSDPGHMNMKGVFLH-----VLSDALGSLIVVGSALVVWL-TEWKYKHYIDPXXXXXXX 235
+ ++ + +H VL D S+ V+ ++ ++W+ WK DP
Sbjct: 357 GENGKNKKGVRNINVHSAYIHVLGDCFQSIGVMVASCIIWVHPHWK---IADPITTLIFS 413
Query: 236 XXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIAS 295
LLRES +L++ VP I V ++ L +EGV VH+ H+W + R S
Sbjct: 414 VIVLGTTIKLLRESLGVLMEGVPPEIDVSEVKGDLSEIEGVTEVHDLHIWSITLGRPALS 473
Query: 296 AHIRCR---NLSEYMKIAEKVKEFFHNEGIHSTTIQPE 330
H+ + E + IA K+ + I+ TTIQ E
Sbjct: 474 VHLTILPTIDPEEILSIANKI--LLEDYEINHTTIQIE 509
>UniRef50_Q54F34 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 770
Score = 98.3 bits (234), Expect = 3e-19
Identities = 78/293 (26%), Positives = 127/293 (43%), Gaps = 11/293 (3%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP-KKWSKN 68
R+ L + F FVE+ G TNS+ L+ D+ HM D AL IA ++ +S K+ K
Sbjct: 404 RIFTFLVINLMFMFVEMAYGIWTNSLGLITDACHMFFDATALFIALVAEVISQWKQNDKY 463
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXX 128
++G+ R +VL VN +FL+ + +I +E+V+R +E I+ K
Sbjct: 464 SYGYGRFQVLSGFVNGIFLIFIAVTILMESVERLLEPPEINTDKLLLVSVLGFIINLIGI 523
Query: 129 XXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGH 188
S+ + H + D K K S
Sbjct: 524 FSFHGDHGHSHGGGGGHSHGGGEKKEKHHGHSHGGHGDHQQVTPILGEEKKKKRS----- 578
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N+ GVFLH+L+D LGS+ V+ S+L++ + W Y DP PL+
Sbjct: 579 VNIDGVFLHLLADTLGSVGVIVSSLIIQI--WGYT-LADPICSLLISILIFLSVLPLIAN 635
Query: 249 SSLILLQTVPTHIQ--VDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIR 299
++ LLQ P IQ + I + + +++GV + +H W D IA+ I+
Sbjct: 636 TAKTLLQCTPEPIQSSLYQINQFILSIDGVHNIISYHFWSHYDDMNIATLKIQ 688
>UniRef50_A7NYR7 Cluster: Chromosome chr6 scaffold_3, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr6 scaffold_3, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 382
Score = 97.5 bits (232), Expect = 5e-19
Identities = 74/299 (24%), Positives = 134/299 (44%), Gaps = 12/299 (4%)
Query: 7 KKCRLLCMLCLTGGFFF-VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP-KK 64
K R LC L + F VE++ G +NS+A++ D+ H+LSDV I+ +V S +
Sbjct: 56 KSSRKLCGLIIFYLIFMAVEIVGGIKSNSLAVLTDAAHLLSDVFGFSISLFAVWASGWRA 115
Query: 65 WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXX 124
S+ +FG+ R EVLGAL + + + + EAV R + N K
Sbjct: 116 TSQQSFGFNRVEVLGALFSVQLIWLIAGILIYEAVNRILHQHAKVNGKLMFAIAAFGFIS 175
Query: 125 XXXXXX-XXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSS 183
H + H + + H+ + E+D+ + ++ K SS
Sbjct: 176 NLIMVTWLGHDHTHHDCGHKDH--DHDHHDYHDHHHHHHHESDKPCSMDEEESTKLVSSS 233
Query: 184 SDPG---HMNMKGVFLHVLSDALGSLIVVGSALVVWLT-EWKYKHYIDPXXXXXXXXXXX 239
+ ++N++G +LHV++D + S+ V+ + ++W EW +D
Sbjct: 234 PEKTKILNINLQGAYLHVMADLIQSVGVMVAGGIIWAKPEWLM---VDLVCTLCFSVLVL 290
Query: 240 XXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+LR IL++ P I + ++ LK+++GV VH+ HVW + +++ S H+
Sbjct: 291 TTTLTMLRNIFSILMERAPIEIDIAGLENGLKSIKGVQDVHDLHVWAITVGKVVMSCHV 349
>UniRef50_Q0EWA1 Cluster: Cation efflux transporter; n=1;
Mariprofundus ferrooxydans PV-1|Rep: Cation efflux
transporter - Mariprofundus ferrooxydans PV-1
Length = 301
Score = 94.3 bits (224), Expect = 4e-18
Identities = 45/142 (31%), Positives = 76/142 (53%), Gaps = 3/142 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N + F HV+ DALGS+ V + +V++ T W IDP W L+RE
Sbjct: 147 INSRAAFWHVVGDALGSVAAVIAGVVIYFTGWMP---IDPILSFLVAAILAWGGWRLIRE 203
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
++ L++ VP I + ++ LK V+G+ +H H+W+L R+ SAH+ ++SE+ +
Sbjct: 204 TTAELMEAVPDAIDTEVVEACLKAVQGISDIHHIHLWKLPDGRMGMSAHVEIESMSEWDE 263
Query: 309 IAEKVKEFFHNEGIHSTTIQPE 330
I + E +G+ T+QPE
Sbjct: 264 ILPLLLEKLRKQGVDHATLQPE 285
Score = 61.3 bits (142), Expect = 4e-08
Identities = 42/96 (43%), Positives = 55/96 (57%), Gaps = 1/96 (1%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNTFGWA 73
L LT F VELI G I+NS+AL+AD+ HM SDV AL +A + +++ K S T+G+
Sbjct: 24 LGLTLLFAIVELIGGLISNSLALLADAAHMSSDVIALALAAFAGRLALKPAHSGMTYGYG 83
Query: 74 RAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
RA VL A +N L L IT EA R +H
Sbjct: 84 RARVLSAQLNGFALWFLSGWITWEATGRLSAPPAVH 119
>UniRef50_Q9VKA3 Cluster: CG31860-PA; n=4; Diptera|Rep: CG31860-PA -
Drosophila melanogaster (Fruit fly)
Length = 669
Score = 93.5 bits (222), Expect = 8e-18
Identities = 69/325 (21%), Positives = 146/325 (44%), Gaps = 23/325 (7%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-T 69
+ C+LC F +E+I G ++NS+A+ D+ H+L+D+A+ +I+ ++ ++ + S+
Sbjct: 311 IACILCTI--FLILEVIGGILSNSLAIATDAAHLLTDLASFLISISALHLAGRPSSERLN 368
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXX 129
+GW RAEV+GA+V+ F+ + + A+ R++ + + K
Sbjct: 369 YGWHRAEVIGAMVSIFFIWVVTGILVYMAIMRWVNQDFELDAKIMLITSALAILF----- 423
Query: 130 XXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSS-SDPGH 188
NV ++ + ++ G + + + K KS + GH
Sbjct: 424 ---------NVIMAMQLQHGHSHSLPGVHKMSKDAGSVLGSKMILLLGKSVSMQYAAKGH 474
Query: 189 --MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
+N++ +HV+ D + S V +AL+++ W ++D + +L
Sbjct: 475 ENINVRAAIIHVVGDIIQSFGVFVAALIIFF--WPEWAFMDSVCTFVFSVLVLVVTFKIL 532
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEY 306
R+ ++L++ P + + +++ ++ GV VH +W L+ +++ SAH+ ++
Sbjct: 533 RDVLMVLMEATPDFMDYEEVKQTFLSISGVEHVHNLRIWALSINKVALSAHLAISKDADP 592
Query: 307 MKIAEKVKEFFHNE-GIHSTTIQPE 330
I E+ H TTIQ E
Sbjct: 593 QLILEEATTLIHKRFKFFETTIQIE 617
>UniRef50_Q7S9J7 Cluster: Putative uncharacterized protein
NCU07709.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU07709.1 - Neurospora crassa
Length = 228
Score = 93.5 bits (222), Expect = 8e-18
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 2/141 (1%)
Query: 199 LSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVP 258
+ DA+ +L V+ +AL++WL + + + Y DP PL++ S ILL++ P
Sbjct: 1 MGDAINNLGVIVAALLIWLLKSEARFYADPGVGVGIAIMIILSSVPLIKNSGEILLESAP 60
Query: 259 THIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR--NLSEYMKIAEKVKEF 316
++ D I+ ++ V GV ++HE HVW+L ++ IAS H+ + +M A + E
Sbjct: 61 KGVRTDDIKHDIEKVPGVDSIHELHVWRLDQNKAIASVHVVLTEDGIVNFMDKARTIGEC 120
Query: 317 FHNEGIHSTTIQPEFVEGPQD 337
H GIHS T+QPE G ++
Sbjct: 121 LHAYGIHSATVQPELSPGYEE 141
>UniRef50_Q1E3Q4 Cluster: Predicted protein; n=1; Coccidioides
immitis|Rep: Predicted protein - Coccidioides immitis
Length = 289
Score = 89.8 bits (213), Expect = 9e-17
Identities = 71/259 (27%), Positives = 115/259 (44%), Gaps = 20/259 (7%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNT 69
RLL ++ ++ F E VG+ T S++LVAD+FH +D+ + ++AFL+ K S + N
Sbjct: 17 RLLIVIAVSFSFVMGEFGVGFKTRSLSLVADAFHYTADIFSFMVAFLAEKYSRRPDENNK 76
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXX 129
G+AR L A N+V LVA+ I ++ ++RFI + I +P
Sbjct: 77 RGYARLPTLAAFFNSVVLVAIGLGIFLQGIERFIHLQAISSPLLVFVMGWAGLFLNIICI 136
Query: 130 XXXHVPPPSNVRHLTEIVNSNADR--ALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPG 187
+ P + H D A G +S D + TQN ++ +S
Sbjct: 137 LI--MGPHGHHHHHGHGHGHGHDHPVAGGQSSADADPNRLEPAPGGTQNARTTGTS---- 190
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKY-----------KHYIDPXXXXXXXX 236
+++K V LH+ +DAL ++ V+ SA +VW ++ K Y DP
Sbjct: 191 -LSIKAVVLHIGADALNNVAVIISAAIVWRIPSRHEEIDPADTREAKFYADPACTVFIAI 249
Query: 237 XXXXXXWPLLRESSLILLQ 255
WPL+ S LL+
Sbjct: 250 LIMGTTWPLVVRSGKALLR 268
>UniRef50_Q4SHM2 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 5 SCAF14581, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 402
Score = 89.4 bits (212), Expect = 1e-16
Identities = 73/285 (25%), Positives = 128/285 (44%), Gaps = 17/285 (5%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLG 79
F E+I GY++NS+A++ D+ HML+DV ++ + L++ +S + +K TFG R EV+
Sbjct: 127 FMTAEIIGGYLSNSLAIMTDAVHMLTDVVGILFSLLALWLSNRPPTKRFTFGLHRLEVIS 186
Query: 80 ALVNAVFLVALCFSITVEAVKRFI--EFEVIHNPKXXXXXXXXXXXXXXXXXXXXHVPPP 137
AL++ + L + EAV R I EF++ +
Sbjct: 187 ALLSVALIYILTAILVYEAVLRTISQEFDIDGDVMLIVAAIGVAVNIIMGFLL------- 239
Query: 138 SNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLH 197
+ HL +S+ GH+ + +H + S + G M ++ F+H
Sbjct: 240 NQDGHLHGHGHSHGH---GHSHGHGHGHGHSHSRGHGHSHGASGSPAPHGSMAVRAAFIH 296
Query: 198 VLSDALGSLIVVGSALVV-WLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQT 256
L D S+ V+ +A VV + E K DP ++R++ +I+L+
Sbjct: 297 ALGDLFQSVGVLVAAYVVRFKPELK---LADPICTYVFSVLVLVTTVRIIRDAMVIVLEG 353
Query: 257 VPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR 301
VP H+ ++ L ++ V AV E +VW L D+ A H++ R
Sbjct: 354 VPRHLDSLQMKEDLLKLDDVQAVDELNVWALTTDKTAALVHLQLR 398
>UniRef50_Q3SKU3 Cluster: Cation efflux protein; n=4;
Proteobacteria|Rep: Cation efflux protein - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 313
Score = 89.0 bits (211), Expect = 2e-16
Identities = 48/143 (33%), Positives = 76/143 (53%), Gaps = 4/143 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N + LHVL DALGS+ + + +VV T W IDP LLRE
Sbjct: 153 LNSRAALLHVLGDALGSVAAIAAGIVVVTTGWTP---IDPLLSILVAVLILVSALRLLRE 209
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
+L++ VP ++++A+ R L ++GV+ VH+ HVW L+ + SAH+ R+L+++
Sbjct: 210 VVHVLMEGVPLDVELEAVGRDLAALDGVLRVHDLHVWTLSTGTVALSAHLELRDLADWPG 269
Query: 309 I-AEKVKEFFHNEGIHSTTIQPE 330
I A ++ GI T+QPE
Sbjct: 270 ILAAARRDMDARHGIRHVTLQPE 292
Score = 58.8 bits (136), Expect = 2e-07
Identities = 35/101 (34%), Positives = 62/101 (61%), Gaps = 1/101 (0%)
Query: 2 GRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMS 61
G ++G LL L LT F +E G + S+AL++D+ HM++D +AL +A + ++
Sbjct: 16 GAHAGGSRTLLVALLLTLAFAGIEAAAGLWSGSLALLSDAAHMVADSSALGLAAAAAWLA 75
Query: 62 PKKWS-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
+ S ++++G RAEVL AL+N++ ++ L I EA++R
Sbjct: 76 RRPPSMRHSYGLVRAEVLAALLNSLLVLVLVGFIVHEALER 116
>UniRef50_A5VLM8 Cluster: Cation diffusion facilitator family
transporter; n=3; Lactobacillus|Rep: Cation diffusion
facilitator family transporter - Lactobacillus reuteri
F275
Length = 306
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/153 (30%), Positives = 83/153 (54%), Gaps = 7/153 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N+K +LH+LSDAL S+ V+ +++ + +DP WP++ +
Sbjct: 139 LNVKATYLHILSDALSSVAVIIGGIILTFVNVPW---LDPALTIGVALYIAYEAWPIINQ 195
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN--LSEY 306
+ IL+Q+ P + ++I+ LK ++GV AVH H W + RII SAH+ C + LS+
Sbjct: 196 TIKILMQSSPD-LDYNSIENDLKQIDGVTAVHHVHAWMMDEHRIIFSAHLNCDDLPLSQV 254
Query: 307 MKIAEKVKEFFHNE-GIHSTTIQPEFVEGPQDE 338
+I +V++ + + GI TIQ E+ G ++
Sbjct: 255 ERIYSQVEKILYEKYGICHVTIQAEYHRGKDEK 287
Score = 64.1 bits (149), Expect = 5e-09
Identities = 29/93 (31%), Positives = 58/93 (62%), Gaps = 1/93 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
R L + L VE++ G ++ S+AL++D+FH L D ++++ + + + + ++
Sbjct: 9 RFLAVPLLNVLITIVEILGGILSGSLALLSDAFHNLGDSLSIVLGYFAQHIGGQPENRQR 68
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
T+G+ RAE+L AL N++FL+ + + +EA+KR
Sbjct: 69 TYGYRRAEILSALTNSIFLIVISVFLIIEAIKR 101
>UniRef50_Q7NRV3 Cluster: Probable cation efflux system; n=1;
Chromobacterium violaceum|Rep: Probable cation efflux
system - Chromobacterium violaceum
Length = 336
Score = 85.8 bits (203), Expect = 2e-15
Identities = 42/144 (29%), Positives = 71/144 (49%), Gaps = 4/144 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N + LHVL D GS + S +V++LT W DP W L+R+
Sbjct: 175 LNSRAALLHVLGDLFGSAAAIASGVVIYLTGWMAA---DPLLSMLVALMLLAAAWRLIRQ 231
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
+ ++L++ VP H+ + I L + GV +VH+ HVW ++ +R+ SAH+R ++ +
Sbjct: 232 AVMVLMEGVPPHLDYNRIGEALSAIAGVRSVHDLHVWTMSAERVALSAHVRIAAPQDWPR 291
Query: 309 IAEKVKEFFHNE-GIHSTTIQPEF 331
I + E I T+Q E+
Sbjct: 292 ILAACQLMLSREFCIDHVTLQAEW 315
Score = 68.5 bits (160), Expect = 2e-10
Identities = 36/91 (39%), Positives = 60/91 (65%), Gaps = 1/91 (1%)
Query: 14 MLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGW 72
+L LT GF VE + G+ + S+AL++D+ HML+D +L++A + ++ + ++ +FG
Sbjct: 50 VLALTCGFALVEALGGWWSGSLALLSDAGHMLTDSLSLLLALWAARIGRRPATERLSFGH 109
Query: 73 ARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
RAEVLGAL+N++ L L I EAV+R +
Sbjct: 110 GRAEVLGALLNSLLLFGLSAFIVAEAVERLL 140
>UniRef50_Q1R0K1 Cluster: Cation diffusion facilitator family
transporter; n=2; Proteobacteria|Rep: Cation diffusion
facilitator family transporter - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 327
Score = 85.4 bits (202), Expect = 2e-15
Identities = 46/147 (31%), Positives = 73/147 (49%), Gaps = 4/147 (2%)
Query: 185 DPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWP 244
D ++N++G LHV+ D LGS+ + ++LV+ T W IDP W
Sbjct: 166 DHENLNLRGALLHVMGDLLGSVAAIVASLVIMATGWMP---IDPLLSMLAAALILRGAWK 222
Query: 245 LLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR-NL 303
++R S LL+ P I VD I+ L+++EGV++VH+ HVW L + S H+ R ++
Sbjct: 223 IVRRSGHTLLEGTPEGIDVDGIRAALEDIEGVVSVHDLHVWGLTPQDPLLSLHLVVRDDM 282
Query: 304 SEYMKIAEKVKEFFHNEGIHSTTIQPE 330
S + + GI T+Q E
Sbjct: 283 SHAVMLKAAYARLHERFGISHATLQVE 309
Score = 68.5 bits (160), Expect = 2e-10
Identities = 40/104 (38%), Positives = 60/104 (57%), Gaps = 2/104 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-N 68
R+ + LT GF E I G+I+ S+AL+AD+ HM SD +L +A + M K K
Sbjct: 40 RVKLAMYLTAGFMLAEAIGGWISGSLALLADAGHMFSDSFSLGLALFAFYMGDKAPDKRR 99
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE-FEVIHNP 111
TFG+ R +VL A +N + L+ + I + AV+RF + EV+ P
Sbjct: 100 TFGYQRFQVLAAFINGLTLLGIAVWILIAAVQRFFQPVEVMAAP 143
>UniRef50_O67168 Cluster: Cation efflux system; n=1; Aquifex
aeolicus|Rep: Cation efflux system - Aquifex aeolicus
Length = 308
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/146 (30%), Positives = 77/146 (52%), Gaps = 9/146 (6%)
Query: 188 HMNMKGVFLHVLSDALGSL--IVVGSALVVWLTEWKYKHYI-DPXXXXXXXXXXXXXXWP 244
++N+K LHV +D LGS+ I+ G A+V W K Y+ DP +
Sbjct: 137 NINIKSALLHVATDTLGSVAAIIAGIAIVFW------KFYLADPILSVAVALLILPSAYS 190
Query: 245 LLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLS 304
+++E+ +LL+ P+HI + +++ L N++GV VH+ HVW + + + H+ + S
Sbjct: 191 VIKETVNVLLEVAPSHINTEELEKELLNLQGVKGVHDLHVWSITPGTEVLTVHVVVEDTS 250
Query: 305 EYMKIAEKVKEFFHNEGIHSTTIQPE 330
I ++V++ H GI TT+Q E
Sbjct: 251 ICNDILKEVEKIAHKYGIKHTTVQLE 276
Score = 72.9 bits (171), Expect = 1e-11
Identities = 38/83 (45%), Positives = 56/83 (67%), Gaps = 1/83 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNTFGWARAEVLG 79
F F+E + G +TNS+AL++D+ HML+D +L IA ++ ++ K K + T+G R EVL
Sbjct: 20 FAFIEFLGGLLTNSLALLSDAGHMLTDAVSLSIALVAQYLALKVKTKRTTYGLYRLEVLA 79
Query: 80 ALVNAVFLVALCFSITVEAVKRF 102
ALVN VFL+ L I +EA+ RF
Sbjct: 80 ALVNGVFLLGLIGYIILEAIHRF 102
>UniRef50_A6SYW0 Cluster: Cobalt-zinc-cadmium resistance protein
CzcD; n=1; Janthinobacterium sp. Marseille|Rep:
Cobalt-zinc-cadmium resistance protein CzcD -
Janthinobacterium sp. (strain Marseille) (Minibacterium
massiliensis)
Length = 316
Score = 84.6 bits (200), Expect = 3e-15
Identities = 49/162 (30%), Positives = 80/162 (49%), Gaps = 7/162 (4%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
SS +N+KG +L V SD LGS+ V+ AL++ T W + +D
Sbjct: 140 SSGKDASLNIKGAYLEVWSDMLGSVGVIAGALIIRFTGWTW---VDSVIAVGIGFWVLPR 196
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR 301
W LLRES +LL+ VP HI ++ +++ + ++ GV ++H+ HVW + +I + H+
Sbjct: 197 TWILLRESINVLLEGVPEHIDLEKLRKSVSDIAGVRSIHDLHVWSITSGKISLTMHV-VG 255
Query: 302 NLSEYMK---IAEKVKEFFHNEGIHSTTIQPEFVEGPQDENE 340
+L + + + E IH TTIQ E Q N+
Sbjct: 256 DLEAFNRDRLLTEIQTTLAEQWEIHHTTIQMEAEACDQATND 297
Score = 71.7 bits (168), Expect = 3e-11
Identities = 37/93 (39%), Positives = 58/93 (62%), Gaps = 1/93 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKNT 69
LL LT F E+I G +T S+AL++D+ HML+D +AL IA ++++++ + S+ T
Sbjct: 18 LLIAFVLTSTFLVAEVIGGLVTGSLALLSDAAHMLTDASALAIALIAIQIAKRAADSRRT 77
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
FG+ R E+L A NA+ L + I EA +RF
Sbjct: 78 FGYHRFEILAASFNAIMLFFVAMYILYEAYRRF 110
>UniRef50_UPI0000499CA1 Cluster: cation diffusion facilitator family
protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
cation diffusion facilitator family protein - Entamoeba
histolytica HM-1:IMSS
Length = 437
Score = 84.2 bits (199), Expect = 5e-15
Identities = 42/147 (28%), Positives = 75/147 (51%), Gaps = 1/147 (0%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
S+ ++N+KGVF+HV DALGS+ + AL V+L +K+Y+DP
Sbjct: 274 STKKKNINIKGVFIHVFGDALGSVATIFVALCVYLINGHWKYYLDPISSLIVSLVMMVSG 333
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC-R 301
PLL I++Q VP ++ I+ + V+ VH+ H+WQL +A+ +
Sbjct: 334 MPLLYSCIRIVMQVVPKRFDLEKIRESILEHPDVVGVHDLHIWQLNNKIGVATLKVELNE 393
Query: 302 NLSEYMKIAEKVKEFFHNEGIHSTTIQ 328
++ +++ +++ +N I TTI+
Sbjct: 394 KVASQGSVSDDIRKILNNNDIPLTTIE 420
Score = 76.2 bits (179), Expect = 1e-12
Identities = 36/103 (34%), Positives = 65/103 (63%), Gaps = 1/103 (0%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KN 68
RL ++ + +F ELI+G NS+ L DSF+MLSD+ + II + + + +S K
Sbjct: 63 RLSFVMVMNFCYFLFELIIGLYLNSLILTVDSFNMLSDILSQIIGLTATIIMKQNFSSKF 122
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
T+G+ RAEV GA +N+VF +++ +++++++ F E E + +P
Sbjct: 123 TYGFTRAEVTGAFINSVFQISIGLFMSIQSIESFFELEEVKDP 165
>UniRef50_A0B5Z8 Cluster: Cation diffusion facilitator family
transporter; n=1; Methanosaeta thermophila PT|Rep:
Cation diffusion facilitator family transporter -
Methanosaeta thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 298
Score = 83.8 bits (198), Expect = 6e-15
Identities = 45/151 (29%), Positives = 77/151 (50%), Gaps = 7/151 (4%)
Query: 184 SDPGHM---NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXX 240
S GHM N++ LHVL DA SL V+ +ALV+W T W + DP
Sbjct: 135 SRDGHMDDLNLRSAILHVLGDAAASLGVIAAALVIWRTGW---YPADPIISLLISVMIFA 191
Query: 241 XXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC 300
+ L+++S ++++ VP I+ D + ++ GV+ VH+ H+W + I+ SAH+
Sbjct: 192 GSYRLIKDSFRLIMEGVPECIRTDEVVDQISTASGVIQVHDLHIWGVCSSNILLSAHVVV 251
Query: 301 RNLSEYMKIAEKVKEFFHN-EGIHSTTIQPE 330
S++ + ++++ + GI TIQ E
Sbjct: 252 SPESDHQRTLSEIRDKLSSIFGIEHATIQLE 282
Score = 52.0 bits (119), Expect = 2e-05
Identities = 29/100 (29%), Positives = 57/100 (57%), Gaps = 1/100 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
R + LT EL+ + T S+AL++D+ H+ D+ AL +++ ++++S S+
Sbjct: 12 RFSLAMILTISILIAELLGSWWTGSLALLSDAAHVFLDLFALGLSWFAIRISALPASERY 71
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
++G+ R EV+ AL N + L + I +EA +R ++ E +
Sbjct: 72 SYGFHRFEVIAALANGLTLGFVALVILIEAYRRLLQPEPV 111
>UniRef50_Q83EH0 Cluster: Cation-efflux family protein; n=3;
Coxiella burnetii|Rep: Cation-efflux family protein -
Coxiella burnetii
Length = 297
Score = 83.4 bits (197), Expect = 8e-15
Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 4/143 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++ V LHV+SD +G+ V+ S +V++ + W IDP L RE
Sbjct: 146 LNIRAVLLHVVSDIVGTCAVLLSGIVIFFSHWAL---IDPLLSVLIGILIIISSVRLWRE 202
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
S +L++ VP H+ + + + + EGV AVH+ H+W L+ SAH+ +N++ +
Sbjct: 203 SMTVLMEGVPAHLNIKQVSQTMVRFEGVKAVHDVHIWTLSSGVTALSAHVNIKNITSWDD 262
Query: 309 IAEKVKEFFHNE-GIHSTTIQPE 330
+ +K + I T+QPE
Sbjct: 263 VLLGLKSTLKQQYDIDHITLQPE 285
Score = 68.5 bits (160), Expect = 2e-10
Identities = 37/98 (37%), Positives = 61/98 (62%), Gaps = 3/98 (3%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAAL-IIAFLS-VKMSPKKWSKNTFGW 72
+ LT GF VE + GY +S+AL+ D+ HM SD AL I AF S + + P K+++G+
Sbjct: 22 ILLTLGFALVEALGGYFAHSLALLGDAGHMASDAVALGIAAFASWIALRPPS-HKHSYGF 80
Query: 73 ARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
RAEV+ A +++ +V + ++ VEA+KR + +H+
Sbjct: 81 GRAEVIAAWASSLLMVIIALAVIVEAIKRIQQPSSVHS 118
>UniRef50_Q1GPY2 Cluster: Cation diffusion facilitator family
transporter; n=7; Proteobacteria|Rep: Cation diffusion
facilitator family transporter - Sphingopyxis alaskensis
(Sphingomonas alaskensis)
Length = 312
Score = 83.4 bits (197), Expect = 8e-15
Identities = 42/102 (41%), Positives = 67/102 (65%), Gaps = 1/102 (0%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKN 68
RLL L LTG F E++ ++ NS+AL++D+ HML+DVAALIIA +++++ + +
Sbjct: 31 RLLLALILTGTFLVAEVVGSFVFNSLALLSDAGHMLTDVAALIIALMAIRIGARPADDQR 90
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
TFG+ R E+L A NA+ L A+ + VEA+ RF + E + +
Sbjct: 91 TFGYRRFEILAAAFNALMLFAVAIYVLVEALNRFRDPEPVQS 132
Score = 76.6 bits (180), Expect = 9e-13
Identities = 43/150 (28%), Positives = 72/150 (48%), Gaps = 4/150 (2%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
SS +N+KG +L V +D LGS+ V+ A+ + T +IDP
Sbjct: 154 SSGKEQSLNLKGAYLEVWADMLGSIGVIAGAIAIRFTG---ATWIDPVVAVGIGLWVLPR 210
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR 301
W LLR+++ +LL+ VP + +D ++R + V GV + H+ HVW + + S HI
Sbjct: 211 TWILLRDTANVLLEGVPRGMSLDEVRRAISEVSGVQSAHDLHVWSITTGNVSCSVHIVVE 270
Query: 302 NLSEYMKIAEKVKEFFHNE-GIHSTTIQPE 330
++++ +V + I TIQ E
Sbjct: 271 DIAQAEPTRTRVAQMLAQAFQIGHATIQTE 300
>UniRef50_A4XA76 Cluster: Cation diffusion facilitator family
transporter; n=3; Actinomycetales|Rep: Cation diffusion
facilitator family transporter - Salinispora tropica
CNB-440
Length = 305
Score = 83.4 bits (197), Expect = 8e-15
Identities = 44/110 (40%), Positives = 60/110 (54%), Gaps = 3/110 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N+KG +L LSD LGSL V+ +AL++ T W+ DP W L R
Sbjct: 153 INLKGAYLEALSDLLGSLSVIAAALIIAGTGWQLA---DPLIAVALGLFRLPRIWLLGRA 209
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
++ IL+Q P H+QV A+Q RL V GV VH+ HVW L + SAH+
Sbjct: 210 ATRILVQAAPEHLQVTAVQDRLIAVPGVTDVHDLHVWTLTSGIEVTSAHL 259
Score = 57.6 bits (133), Expect = 5e-07
Identities = 34/95 (35%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAAL--IIAFLSVKMSPKKWSK 67
RL L G E + T S+ L+ D+ HM +DV + +A L++ K +
Sbjct: 22 RLWTAFTLLGTLMVAEAVTAVRTGSLTLLGDAGHMFTDVLGIGMSLAALTLTSQRGKNPQ 81
Query: 68 NTFGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
TFG R EVL AL NA+ L A+ + VEA++RF
Sbjct: 82 RTFGLYRVEVLAALTNALMLSAVSIYVLVEAIRRF 116
>UniRef50_A3GEZ3 Cluster: Meiotic Sister-Chromatid recombination
transmembrane protein (Putative) showing some protein
similarity to Zrc1p and Cot1p; n=4;
Saccharomycetales|Rep: Meiotic Sister-Chromatid
recombination transmembrane protein (Putative) showing
some protein similarity to Zrc1p and Cot1p - Pichia
stipitis (Yeast)
Length = 631
Score = 83.4 bits (197), Expect = 8e-15
Identities = 71/313 (22%), Positives = 119/313 (38%), Gaps = 16/313 (5%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS---KNTFG 71
L L F FV+L+ + + S+ L++DS HM D +L + ++ +S K+ + K FG
Sbjct: 302 LLLNATFMFVQLLHSFRSKSLGLLSDSLHMALDCMSLALGLIAGALSKKEINPHGKYPFG 361
Query: 72 WARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXXXX 131
E+L N L+ + I EA+ R + V+
Sbjct: 362 LKNFEILAGFTNGTLLIGISGGIIFEAIGRLVNPVVLEKTTELIIVSLLGLGVNLVGIFA 421
Query: 132 XHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNM 191
+ H + GHN + + + H+ CK NM
Sbjct: 422 FNHGHAHGHSH-------GHSHSHGHNHEHESGHSHNHEHSHGEEHEDCKEEGGMND-NM 473
Query: 192 KGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE--S 249
KG+FLH+L+D LGS+ VV S ++ +W + DP PL++ S
Sbjct: 474 KGIFLHILADTLGSVGVVVSTILTKYVKW---NGFDPIASMIIATLILLSAIPLIQSTAS 530
Query: 250 SLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKI 309
SL+L T +V + N++G+ + W + + I HI+ I
Sbjct: 531 SLLLRLTKKKETKVRNALNDITNIKGIKSFTTPRFWPNSSNTINGYIHIQVYRGENASYI 590
Query: 310 AEKVKEFFHNEGI 322
+ + F E I
Sbjct: 591 KRQCERVFETEKI 603
>UniRef50_Q1H0B4 Cluster: Cation diffusion facilitator family
transporter; n=1; Methylobacillus flagellatus KT|Rep:
Cation diffusion facilitator family transporter -
Methylobacillus flagellatus (strain KT / ATCC 51484 /
DSM 6875)
Length = 325
Score = 82.6 bits (195), Expect = 1e-14
Identities = 42/147 (28%), Positives = 70/147 (47%), Gaps = 6/147 (4%)
Query: 187 GH--MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWP 244
GH +N + LHVL D LGS+ + + V++ T W IDP
Sbjct: 144 GHSSLNSRAALLHVLGDLLGSVAAILAGAVIYFTGWMP---IDPILSIFISVLILVSTLR 200
Query: 245 LLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLS 304
LL E +L++ VP H+ + A++ + + V VH H+W L+ ++ SAHI N+
Sbjct: 201 LLGEVLHVLMEGVPLHLDIQAVEHAMSASDKVQGVHHLHIWSLSSEKTALSAHIVLENIL 260
Query: 305 EYMKIAEKVKEFFHNE-GIHSTTIQPE 330
++ ++ ++ H I T+QPE
Sbjct: 261 DWHEVLNNLRHMLHERFNIEHVTLQPE 287
Score = 72.5 bits (170), Expect = 2e-11
Identities = 42/102 (41%), Positives = 64/102 (62%), Gaps = 1/102 (0%)
Query: 4 YSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK 63
+ G + LL L L GF VE + G+ T S+AL++D+ HM+SD AL +A+L ++ K
Sbjct: 13 HGGGQPSLLLPLLLIAGFAVVEAVGGWWTGSLALLSDAGHMVSDAFALALAWLGSWIARK 72
Query: 64 KWS-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+ K+ FG RAEV+ ALVNA+ ++A+ I EAV+R +
Sbjct: 73 PATRKHNFGLVRAEVIVALVNALLMLAVIGGIAYEAVQRIAD 114
>UniRef50_A4SX31 Cluster: Cation diffusion facilitator family
transporter; n=1; Polynucleobacter sp. QLW-P1DMWA-1|Rep:
Cation diffusion facilitator family transporter -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 626
Score = 82.6 bits (195), Expect = 1e-14
Identities = 51/159 (32%), Positives = 75/159 (47%), Gaps = 6/159 (3%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
S D +N + +HV+ D LGS+ + + +V+ LT W ID
Sbjct: 170 SRDTKSVNTRAALVHVMGDLLGSVAALIAGIVIQLTGWMP---IDAILSILVSLLILKST 226
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN 302
+L ES L++ VP HI A+ R LK V GV+AVH+ HVW++ HI +
Sbjct: 227 ISILHESYHFLMEGVPLHIDYLAVGRDLKAVPGVLAVHDLHVWEMTPSFPALIGHIEISD 286
Query: 303 LSEYMKIAEKVKE-FFHNEGIHSTTIQPEFVEGPQDENE 340
+ E+ I K+ GI T+QPE E QDE++
Sbjct: 287 MQEWPSIMAKINAMLLDKHGIDHVTLQPE--EVGQDEHD 323
Score = 72.9 bits (171), Expect = 1e-11
Identities = 39/93 (41%), Positives = 61/93 (65%), Gaps = 1/93 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNT 69
+L L LT GF VE Y NS+AL++D+ HM++D AAL +A L+ ++ + S +++
Sbjct: 48 ILIALVLTLGFSGVEGAAAYFANSLALISDAGHMVTDAAALGLALLAQIIARRPPSPRHS 107
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
FG+ RAE L A VN++ ++AL I +EA+ RF
Sbjct: 108 FGFGRAEALAAFVNSIAMLALVLWIVIEAISRF 140
>UniRef50_Q98H85 Cluster: Cation efflux system protein; n=8;
Alphaproteobacteria|Rep: Cation efflux system protein -
Rhizobium loti (Mesorhizobium loti)
Length = 365
Score = 82.2 bits (194), Expect = 2e-14
Identities = 47/150 (31%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 185 DPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWP 244
D +NM+G LHVL D LGS + +A+V+ +T W IDP W
Sbjct: 192 DRESLNMRGAILHVLGDLLGSAAAIVAAVVILVTGWT---PIDPILSVLVSLLILSTAWS 248
Query: 245 LLRESSLILLQTVPTHIQVDAIQRRLK-NVEGVMAVHEFHVWQLAGDRIIASAHIRC--R 301
L+R ++ +LL+ VP + D I L+ ++GV VH HVW + G +A+ H C
Sbjct: 249 LMRAAAHVLLEGVPPSLDRDLIATDLETTIQGVREVHHMHVWSIDGSSNMATLH-ACLDE 307
Query: 302 NLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
+ + ++ K GI T++PEF
Sbjct: 308 GVDAHRAVSAIKKRLASEHGISHATVEPEF 337
Score = 61.3 bits (142), Expect = 4e-08
Identities = 33/97 (34%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
Query: 8 KCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWS 66
K R+L CLT GF E + G T S+AL+AD+ HML+D AL +A+ + ++ +
Sbjct: 64 KKRVLIAACLTAGFMVAEALGGLFTGSLALLADAGHMLADAIALGLAWYAFHLAGRPATG 123
Query: 67 KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
+ T+G+ R + L A N + + + I EA +R +
Sbjct: 124 QLTYGFGRVKTLVAYTNGIAIFVIALWIVYEAWQRLL 160
>UniRef50_Q6M5R5 Cluster: Co/Zn/Cd efflux system transmembrane
protein; n=5; Corynebacterium|Rep: Co/Zn/Cd efflux
system transmembrane protein - Corynebacterium
glutamicum (Brevibacterium flavum)
Length = 324
Score = 81.8 bits (193), Expect = 2e-14
Identities = 49/156 (31%), Positives = 76/156 (48%), Gaps = 6/156 (3%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
G++NM+G FLHVLSD LGS+ V+ + LV+ T W D + LL
Sbjct: 170 GNINMRGAFLHVLSDMLGSVAVIIAGLVIRYTGWMPA---DTIASIAIAAIIIPRAFSLL 226
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI---RCRNL 303
+E+ ILL+ VPT + + L+ V GV VH+ H+W + G I+A+ H+ N
Sbjct: 227 KEALNILLERVPTGAEPAEVDAALRKVPGVSDVHDLHIWSIDGKEILATVHLVVDSSTNQ 286
Query: 304 SEYMKIAEKVKEFFHNEGIHSTTIQPEFVEGPQDEN 339
+ ++ + GI +TIQ E + E+
Sbjct: 287 LHSCGVLDRAEAELSKLGILHSTIQLESADHSDHES 322
Score = 76.6 bits (180), Expect = 9e-13
Identities = 41/92 (44%), Positives = 59/92 (64%), Gaps = 1/92 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNT 69
L ++ T F ELI G I+ S+AL+AD+ HMLSD LIIA +++ + + + S+ T
Sbjct: 43 LFAVIIFTSIIFLAELIAGLISGSLALLADAMHMLSDSTGLIIAAVAMLIGRRARTSRAT 102
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
+G+ RAEVL A+VNA + AL I VEA+ R
Sbjct: 103 YGYKRAEVLAAMVNATVVTALSVWIVVEAIMR 134
>UniRef50_Q6NHN1 Cluster: Cation-efflux system integral membrane
protein; n=1; Corynebacterium diphtheriae|Rep:
Cation-efflux system integral membrane protein -
Corynebacterium diphtheriae
Length = 307
Score = 81.0 bits (191), Expect = 4e-14
Identities = 43/144 (29%), Positives = 78/144 (54%), Gaps = 5/144 (3%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N+KG +LH+L D GS+ V+ S+L++ T W + D L+R
Sbjct: 154 VNVKGAYLHILVDLGGSVAVIVSSLLIMTTGWMW---CDTAVSVLLAVIILPRSLSLVRS 210
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC-RNLS-EY 306
+ IL++ VP + V+ I+ R+ ++GV VH+ HVW + G + IA+ H+ N++ +
Sbjct: 211 TLGILMERVPKTVDVETIRSRIAQIDGVGGVHDVHVWSIDGQQDIATVHVVVDENVNVKD 270
Query: 307 MKIAEKVKEFFHNEGIHSTTIQPE 330
+++++ FH+ GI T+Q E
Sbjct: 271 CTTLDRIQKVFHDAGIDHVTVQLE 294
Score = 77.0 bits (181), Expect = 7e-13
Identities = 43/99 (43%), Positives = 63/99 (63%), Gaps = 1/99 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK-WSKNT 69
LL + LT FF VEL+ G + S+AL++D+ HMLSD LIIA ++V + +K S+ T
Sbjct: 25 LLLVAGLTFAFFIVELVGGALAKSLALMSDALHMLSDSTGLIIALIAVVIGRRKATSQAT 84
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
+G+ R EVL ALVNA+ + + I +EA++R VI
Sbjct: 85 YGYKRIEVLAALVNALSVTFITGWIVLEAIRRLSSHTVI 123
>UniRef50_A0DLG1 Cluster: Chromosome undetermined scaffold_55, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_55,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 574
Score = 80.6 bits (190), Expect = 6e-14
Identities = 50/189 (26%), Positives = 92/189 (48%), Gaps = 15/189 (7%)
Query: 157 HNSTDNEETDEMVK--KAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALV 214
H+ D++E DE K K K +NH + ++ + N+K +HV+ D L S+ V+ +A++
Sbjct: 373 HDHHDHDERDEQTKRRKNKVKNH-NLSEINEHDNYNLKAAMIHVIGDILQSIGVLIAAIL 431
Query: 215 VWLTEWK----------YKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVD 264
+++ K Y Y DP + + +E +L++ PT++ ++
Sbjct: 432 IYIFGQKKDENNEIVFTYWQYADPLCTYLFSILVLFTTFGVAKECVRVLMEGTPTNLIIE 491
Query: 265 AIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHS 324
+ RL + V VH+ H+W L+ + SAHI C EY + +K + GI+
Sbjct: 492 EFRDRLNAIHRVREVHDLHIWSLSVGKPAMSAHIVCLENPEY--VLKKATKLCRKFGIYH 549
Query: 325 TTIQPEFVE 333
+TIQ E ++
Sbjct: 550 STIQIELLD 558
Score = 64.5 bits (150), Expect = 4e-09
Identities = 33/104 (31%), Positives = 60/104 (57%), Gaps = 1/104 (0%)
Query: 9 CRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-K 67
CRL+ + + F E+I G S+A+++D+ HM SD++ I+ S+ ++ + S K
Sbjct: 59 CRLIAVSVVCVVFLIAEVIGGLWAQSLAILSDAAHMFSDMSGFFISIFSIWLAQRPASQK 118
Query: 68 NTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
+FG+ RAEV+GAL + V + L + EA +R + ++ +P
Sbjct: 119 MSFGYHRAEVIGALASIVLIWGLTILLFYEATERMVNQTLVTDP 162
>UniRef50_A6X3Y0 Cluster: Cation diffusion facilitator family
transporter; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
Cation diffusion facilitator family transporter -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 352
Score = 80.2 bits (189), Expect = 7e-14
Identities = 42/116 (36%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Query: 185 DPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWP 244
D H+N+KG LHVL D LGS+ V +A+V+ T W IDP W
Sbjct: 161 DTEHVNIKGAILHVLGDLLGSVAAVSAAIVIMYTGWT---LIDPILSVFVSLLILRAAWN 217
Query: 245 LLRESSLILLQTVPTHIQVDAIQRRL-KNVEGVMAVHEFHVWQLAGDRIIASAHIR 299
LL +S ILL+ P + + I+R L +N+ V +V HVW + R +A+ H+R
Sbjct: 218 LLGKSIHILLEGAPDNATPEKIERHLVENIADVASVSHIHVWSITSGRTLATLHVR 273
Score = 74.1 bits (174), Expect = 5e-12
Identities = 46/103 (44%), Positives = 62/103 (60%), Gaps = 3/103 (2%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW- 65
+K L L LT F VE+I G I+ S+AL+AD+ HMLSD AAL +A+ + + +
Sbjct: 34 RKVLLSFFLILT--FMIVEVIGGLISGSLALLADAGHMLSDAAALALAYAAFRFGRRAAD 91
Query: 66 SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
SK TFG+ R EVL +NA+ L A+ I EA +RF E VI
Sbjct: 92 SKRTFGYLRFEVLAGFINAITLFAIVVWIVYEAWQRFQEPHVI 134
>UniRef50_A5DM54 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 625
Score = 80.2 bits (189), Expect = 7e-14
Identities = 71/283 (25%), Positives = 113/283 (39%), Gaps = 15/283 (5%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLS---VKMSPKKWSKNTFG 71
L L F FV+LI + + S+ L++DS HM D A+L + L+ +K K FG
Sbjct: 299 LLLNSAFMFVQLIYSFRSKSLGLLSDSLHMALDCASLALGLLAGIFLKAPIDSNGKYPFG 358
Query: 72 WARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXXXX 131
E L N LV + SI EA+ R + ++
Sbjct: 359 LKNFETLAGFANGTLLVGISGSIVFEALGRLLNPVLLQKTTELILVSAMGLGVNLVGIFA 418
Query: 132 XHVPPPSNVR---HLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGH 188
H S+ H +S+ + + E D + + S K+ +D
Sbjct: 419 FHGHGHSHGHSHGHSHGYEHSHDEHVHEKLEYEKENHDHYDQNCSHSHSHSQKADND--- 475
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
NM+G+FLH+L+D LGS+ VV S ++ L W + DP PLL+
Sbjct: 476 -NMQGIFLHILADTLGSVGVVVSTILTKLLGW---NGFDPMASIVIAVLIFLSAIPLLKS 531
Query: 249 --SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAG 289
SSL+LL + +V + + ++GV + W +G
Sbjct: 532 TASSLLLLLSTSNEEKVRLVLNDILEIKGVKSFTTPRFWPSSG 574
>UniRef50_UPI0000DAE80F Cluster: hypothetical protein
Rgryl_01001334; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01001334 - Rickettsiella
grylli
Length = 298
Score = 79.8 bits (188), Expect = 1e-13
Identities = 54/153 (35%), Positives = 77/153 (50%), Gaps = 12/153 (7%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N+K FLH+ DAL +L VV + V++ T+W + IDP W LLR
Sbjct: 145 LNIKSAFLHLTYDALIALGVVLAGAVIYFTKWLW---IDPIVGLLIVGIITWGSWNLLRR 201
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC--RNLS-- 304
S ++L VP + I LKN+ GV VH+ H+W L+ +AH+ NLS
Sbjct: 202 SVELILGAVPYGVDSKEIYTYLKNLPGVQEVHDLHIWGLSTQETALTAHLIMPETNLSDE 261
Query: 305 EYMKIAEKVKEFFHNEGIHSTTIQPEFVEGPQD 337
EY KI + + E FH I T+Q E +G +D
Sbjct: 262 EYFKINQVLAEKFH---IQHVTLQVE--QGQKD 289
Score = 56.8 bits (131), Expect = 8e-07
Identities = 31/97 (31%), Positives = 57/97 (58%), Gaps = 7/97 (7%)
Query: 17 LTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAF-LSVKMSPKKWSKNTFGWARA 75
L GF F E++ G+I +S++L++D+ H +DV L++++ SV + + + ++G+ +
Sbjct: 22 LNFGFVFTEVVYGFIAHSVSLLSDAVHNFADVLGLLMSWGASVLIKRRATQRYSYGYKKL 81
Query: 76 EVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
+L AL NA+ LV I E+V R ++NPK
Sbjct: 82 TILAALANALLLVLTSALIIYESVNR------LYNPK 112
>UniRef50_Q5L2G4 Cluster: Cation efflux transporter; n=5;
Bacillaceae|Rep: Cation efflux transporter - Geobacillus
kaustophilus
Length = 315
Score = 79.8 bits (188), Expect = 1e-13
Identities = 40/151 (26%), Positives = 74/151 (49%), Gaps = 4/151 (2%)
Query: 181 KSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXX 240
K ++N++ +LHV+ DALGS+ + + LV+WL W + DP
Sbjct: 157 KKGDVKNNVNLRSAYLHVIGDALGSVGAIIAGLVMWLFSW---YVADPIISILVALLILK 213
Query: 241 XXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC 300
W +++ + IL++ P I + +++ L+++EGV+ VH+ H+W + S HI
Sbjct: 214 GAWGVIKHTVHILMEGTPITIDQNEVKKALESIEGVINVHDLHIWTITSGLDSLSCHILI 273
Query: 301 RNLSEYMKIAEKVKEFFHNE-GIHSTTIQPE 330
+ + K+ ++ F + I TIQ E
Sbjct: 274 EDHQDSQKVLQEAIHFIEDHFKIQHATIQIE 304
Score = 74.9 bits (176), Expect = 3e-12
Identities = 40/98 (40%), Positives = 60/98 (61%), Gaps = 1/98 (1%)
Query: 6 GKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW 65
G K L L +T G +E G ITNS+AL++DS HMLSD ++L+++ +++ + K
Sbjct: 29 GNKKGLTIALLITAGIMLLEFFGGLITNSLALLSDSGHMLSDASSLVLSLVAIWFATKPA 88
Query: 66 SKN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
S N T+G+ R E+L AL N V L + I EA++RF
Sbjct: 89 SPNKTYGFYRFEILAALFNGVTLFVIAGFIIWEAIERF 126
>UniRef50_A5WCY6 Cluster: Cation diffusion facilitator family
transporter; n=2; Psychrobacter|Rep: Cation diffusion
facilitator family transporter - Psychrobacter sp.
PRwf-1
Length = 359
Score = 79.8 bits (188), Expect = 1e-13
Identities = 46/170 (27%), Positives = 84/170 (49%), Gaps = 8/170 (4%)
Query: 172 AKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSAL-VVWLTEWKYKHYIDPXX 230
A +H ++ S ++NM +LHVL D LGS+ + +AL ++W+ W + DP
Sbjct: 167 AHDHDHGHGEAQSGEKNLNMHSAYLHVLGDLLGSVAAIIAALAMMWMGWW----WADPVA 222
Query: 231 XXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGD 290
+ +++ S+ IL++ P I +D ++ +++ E ++AVH+ HVW +
Sbjct: 223 SVIVAVLILMSGFRVVKASTHILMEGTPEEISLDDVKHTIEHNEHIIAVHDLHVWSITSG 282
Query: 291 RIIASAHIRCRNLSEYMKIAEKVKEFFHN---EGIHSTTIQPEFVEGPQD 337
S H+ ++ +E + E H+ GI TTIQ E +E P +
Sbjct: 283 LHALSCHVVVDGDMRILEASELIHELEHSLERLGISHTTIQVESIEHPHN 332
Score = 68.1 bits (159), Expect = 3e-10
Identities = 41/102 (40%), Positives = 59/102 (57%), Gaps = 2/102 (1%)
Query: 3 RYSGKKCRLLCM-LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMS 61
R K+ R+L + GF VE I G +T+S+AL++D+ HMLSD AAL L+ K+
Sbjct: 31 RDMSKQRRILWFSFLIISGFMLVEAIGGLLTHSLALLSDAGHMLSDAAALGATLLAFKIG 90
Query: 62 PKKWS-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
K+ S + TFG+ R E+L A N L+ + I EA+ RF
Sbjct: 91 EKQASNEKTFGYKRFEILVAGANGATLIIIALMIVREAIGRF 132
>UniRef50_Q1AYG3 Cluster: Cation diffusion facilitator family
transporter; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
Cation diffusion facilitator family transporter -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 314
Score = 79.0 bits (186), Expect = 2e-13
Identities = 47/141 (33%), Positives = 68/141 (48%), Gaps = 4/141 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++G HVL+D LGSL V+ S +VV LT W + DP W LLR+
Sbjct: 149 LNLQGALRHVLADLLGSLGVLVSGMVVLLTGW---YPADPLVSAAIGLLILASSWRLLRD 205
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
S ILL+ P + I RR+ + GV VH+ HVW + SAH+ +
Sbjct: 206 SVNILLEAAPHGMDAAEIGRRMASTSGVAEVHDLHVWTITSGFPALSAHVLVAAGEDCHA 265
Query: 309 IAEKVKEFFHNE-GIHSTTIQ 328
++++ E GI TT+Q
Sbjct: 266 KRRELEQLLREEYGISHTTLQ 286
Score = 68.9 bits (161), Expect = 2e-10
Identities = 39/104 (37%), Positives = 63/104 (60%), Gaps = 2/104 (1%)
Query: 2 GRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMS 61
GR + ++ L L +T + E + G++T S+AL+AD+ HMLSD +L +A ++ +S
Sbjct: 12 GREADRRS-LAAALAITASYTVAEAVGGFLTGSLALLADAAHMLSDNFSLGLALFALWLS 70
Query: 62 PK-KWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+ + +FG+ RAE+L AL N V LVA+ I EA +R +E
Sbjct: 71 SRPPTPERSFGYKRAEILAALFNGVTLVAVSLWIFYEAYRRLLE 114
>UniRef50_Q8EZ48 Cluster: Cobalt-zinc-cadmium resistance protein
czcD; n=4; Leptospira|Rep: Cobalt-zinc-cadmium
resistance protein czcD - Leptospira interrogans
Length = 308
Score = 78.6 bits (185), Expect = 2e-13
Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 6/145 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+NMKG +LH+L+D L SL V+ S L++ +W +IDP PL R+
Sbjct: 155 INMKGAYLHLLADGLVSLGVIISGLLI---QWLGFFWIDPVVGLLVGLVILYGNIPLFRQ 211
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN--LSEY 306
S + L + P IQ +++ LK++EGV+ +H H+W L+ +AH+ +N E+
Sbjct: 212 SLRLSLDSTPETIQSGIVEKELKSIEGVLNIHHIHIWSLSTTENALTAHLVLKNDLTFEH 271
Query: 307 MKIAE-KVKEFFHNEGIHSTTIQPE 330
+I + K +E I T++ E
Sbjct: 272 QRIIKSKAREILKGLKIEHVTLETE 296
Score = 54.8 bits (126), Expect = 3e-06
Identities = 23/79 (29%), Positives = 53/79 (67%), Gaps = 1/79 (1%)
Query: 24 VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK-WSKNTFGWARAEVLGALV 82
+E +G + S+AL++D+ H L DV++L++A++++K+ KK + T+GW ++ +L +L+
Sbjct: 39 IEAGIGLTSGSLALLSDAGHNLMDVSSLLLAWIAIKLQEKKPFPGFTYGWKKSTILVSLL 98
Query: 83 NAVFLVALCFSITVEAVKR 101
N++ + I E++++
Sbjct: 99 NSILIFGTVGLIVYESIEK 117
>UniRef50_A3UGA9 Cluster: Cation efflux protein; n=3;
Proteobacteria|Rep: Cation efflux protein - Oceanicaulis
alexandrii HTCC2633
Length = 321
Score = 78.6 bits (185), Expect = 2e-13
Identities = 38/117 (32%), Positives = 60/117 (51%), Gaps = 4/117 (3%)
Query: 184 SDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXW 243
+D ++N++G HV+ D LGS+ + +A V+W T W IDP W
Sbjct: 167 ADTDNLNIRGALAHVMGDLLGSVAAIIAAGVIWWTGWT---PIDPLLSLLIAGLIGISAW 223
Query: 244 PLLRESSLILLQTVPTHIQVDAIQRRL-KNVEGVMAVHEFHVWQLAGDRIIASAHIR 299
L+R++ +LL+ P HI ++ L +E V+ +H HVW L DR +A+ H R
Sbjct: 224 RLVRDAGRVLLEAAPDHIDPSVLRADLTAEIEDVLDIHHVHVWSLTPDRPMATLHAR 280
Score = 73.7 bits (173), Expect = 7e-12
Identities = 40/96 (41%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKN 68
R L LTGGF E+I G +T S+AL+AD+ HML+D AALI+A+ + ++S + K
Sbjct: 42 RTLIAAALTGGFMLAEVIGGLLTGSLALLADAAHMLTDFAALILAWGAFRLSRRPATDKR 101
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
++G+ R ++L A N V L L I EAV R +
Sbjct: 102 SYGYDRLQILAAFANGVTLSILVVWIACEAVMRLFD 137
>UniRef50_Q97G32 Cluster: Co/Zn/Cd efflux system component; n=1;
Clostridium acetobutylicum|Rep: Co/Zn/Cd efflux system
component - Clostridium acetobutylicum
Length = 303
Score = 78.2 bits (184), Expect = 3e-13
Identities = 43/153 (28%), Positives = 81/153 (52%), Gaps = 6/153 (3%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++ +LH+LSDA+ SL V+ S + + ++ ++ID + +L+E
Sbjct: 151 LNVRSSYLHMLSDAMASLAVIISGVFI---KYFAIYWIDSVLTIFINMLILKSSYNILKE 207
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNL--SEY 306
S IL+QT P ++ +D ++ +L ++ + VH FH+W L + I+ HI ++ SE
Sbjct: 208 SINILMQTTPVNLDMDDVKEQLLKIKEIKGVHHFHIWTLDENNIVLEGHIEIDDILVSET 267
Query: 307 MKIAEKVKEFFHNEGIHSTTIQPEFVEGPQDEN 339
I++K+ E NE H T + +F ++N
Sbjct: 268 RAISDKI-EHILNEDFHITHVVIQFESTSCEDN 299
Score = 66.9 bits (156), Expect = 7e-10
Identities = 30/86 (34%), Positives = 59/86 (68%), Gaps = 1/86 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-NTFGWARAEVLGALVN 83
E+I G I+ S++L++D+ H LSD A+LI++++S+K+S K +K T+G+ RA +L A +N
Sbjct: 36 EVIGGSISGSLSLISDALHNLSDTASLILSYVSIKISEKPKNKAKTYGYKRANILAAFIN 95
Query: 84 AVFLVALCFSITVEAVKRFIEFEVIH 109
+ L+ + + V+A+++ + I+
Sbjct: 96 SAALIGISIFLGVQALEKLTSLKKIN 121
>UniRef50_A1RH26 Cluster: Cation diffusion facilitator family
transporter; n=4; Proteobacteria|Rep: Cation diffusion
facilitator family transporter - Shewanella sp. (strain
W3-18-1)
Length = 342
Score = 78.2 bits (184), Expect = 3e-13
Identities = 48/154 (31%), Positives = 75/154 (48%), Gaps = 6/154 (3%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
H+N+KG LHV+ D LGS+ + +A+V++L W IDP W LL
Sbjct: 154 HVNVKGAILHVMGDLLGSVGAIVAAVVIYLIGWT---PIDPILSVLVAALILRSAWKLLA 210
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKN-VEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEY 306
+S ILL+ P + +++ L V G+ AV HVWQL R +A+ H+R E
Sbjct: 211 KSIHILLEGAPEDASPEQVEQGLMGAVPGLAAVSHVHVWQLTSGRTMATLHVRPSVAEEA 270
Query: 307 MKIAEKVKEFFHNE-GIHSTTIQPEFVEGPQDEN 339
+ + V+ + GI T+ E+ P ++N
Sbjct: 271 RTVVKCVEVVLREQFGIEHVTVGIEW-NSPGEKN 303
Score = 65.3 bits (152), Expect = 2e-09
Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKN 68
++L L GF VE + G ++ S+AL+AD+ HML+D AAL +A+ + + + SK
Sbjct: 25 KVLLSFFLIFGFMIVEAVGGVLSGSLALLADAGHMLTDAAALALAYAAFRFGRRPADSKR 84
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
TFG+ R EV+ +NAV L + I EA +R
Sbjct: 85 TFGYLRFEVIAGFLNAVTLFVIVAWIAYEAWER 117
>UniRef50_A4R597 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 309
Score = 78.2 bits (184), Expect = 3e-13
Identities = 42/123 (34%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 217 LTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGV 276
LT + + Y DP PL+R+S ILLQ+VP + + L+ + GV
Sbjct: 133 LTSSEARFYADPAISTFIAIMIFVTAVPLVRKSGEILLQSVPVGLSPSDVTHDLEKIPGV 192
Query: 277 MAVHEFHVWQLAGDRIIASAHIRCRN--LSEYMKIAEKVKEFFHNEGIHSTTIQPE--FV 332
+VH H+W+L + +AS H+ ++ +S++M A V E H GIH+ IQPE F
Sbjct: 193 DSVHHLHIWRLDQTKTVASVHVVVQDEAISDFMTKARTVTECLHAYGIHTAIIQPEVAFH 252
Query: 333 EGP 335
+GP
Sbjct: 253 QGP 255
Score = 46.0 bits (104), Expect = 0.001
Identities = 18/39 (46%), Positives = 29/39 (74%)
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEV 107
+FGW RA +LG+ N VFL+AL SI +++++RF+ E+
Sbjct: 14 SFGWQRATILGSFFNGVFLLALGLSIFLQSIERFVSLEL 52
>UniRef50_Q01NK8 Cluster: Cation diffusion facilitator family
transporter; n=1; Solibacter usitatus Ellin6076|Rep:
Cation diffusion facilitator family transporter -
Solibacter usitatus (strain Ellin6076)
Length = 312
Score = 77.4 bits (182), Expect = 5e-13
Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 6/153 (3%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
+S +N++ F+H+L DALGS+ ++ A+ + T W +DP
Sbjct: 141 ASSKNDINIRSAFVHMLGDALGSVAIIAGAVAIRYTGWLR---VDPVLSIVIALLIVWTA 197
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN 302
W ++RES ILL+ +P I + + + + V GV+ VH+ H+W L S H+ +
Sbjct: 198 WDIIRESLNILLEGLPRGIHLVDVAKAMGGVTGVLGVHDLHIWSLGSKTHALSCHVLIED 257
Query: 303 L--SEYMKIAEKVKEFF-HNEGIHSTTIQPEFV 332
+ S I + H GI TT+Q E V
Sbjct: 258 VPPSASDCILRSLNTLLEHKYGISHTTVQFEHV 290
Score = 58.8 bits (136), Expect = 2e-07
Identities = 33/95 (34%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWA 73
L T F +E++ G +S+AL++D+ H +D A+ +A++ +++ K + T+G+
Sbjct: 22 LLATTVFVLIEVVAGLQAHSLALISDAAHNFTDALAIGLAWVGLRLQTKPADETKTYGYH 81
Query: 74 RAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
RA VL A VNA+ LVAL I E+V R E +
Sbjct: 82 RASVLSAFVNALTLVALSAWILYESVLRLRNPEAV 116
>UniRef50_Q8WQB6 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 746
Score = 77.4 bits (182), Expect = 5e-13
Identities = 44/144 (30%), Positives = 69/144 (47%), Gaps = 3/144 (2%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
G+ NM+GVFLHVL+D LGS+ V+ S L++ W + +DP +PLL
Sbjct: 556 GNANMQGVFLHVLADTLGSVFVIISTLLIQWFGWVW---VDPLCSLILSLLIIGSVYPLL 612
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEY 306
S LLQ VP + + + +E V + H+WQ D +AS H++ + +
Sbjct: 613 VSSISTLLQDVPEEEEFEYHINEILEIEHVESYSNAHMWQHKSDINVASVHVQVKEEANA 672
Query: 307 MKIAEKVKEFFHNEGIHSTTIQPE 330
I +V + G +T+Q E
Sbjct: 673 QMIRHRVSNILKSTGATHSTVQVE 696
Score = 75.4 bits (177), Expect = 2e-12
Identities = 36/98 (36%), Positives = 59/98 (60%), Gaps = 5/98 (5%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
R+ LC+ GF VE + G+ TNS+ L++D FHML D +AL++ ++ M+ +W
Sbjct: 403 RIFWFLCVNLGFCGVEFLYGFWTNSLGLISDGFHMLFDCSALVMGLVASVMA--RWPPTR 460
Query: 69 --TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
TFG+ R E+L +NA+FL + I +EA++R +
Sbjct: 461 HFTFGFGRVEILSGFINALFLCVIALFILIEALERLFD 498
>UniRef50_Q6D7E5 Cluster: Zinc transporter zitB; n=40;
Enterobacteriaceae|Rep: Zinc transporter zitB - Erwinia
carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 320
Score = 77.4 bits (182), Expect = 5e-13
Identities = 40/101 (39%), Positives = 64/101 (63%), Gaps = 1/101 (0%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
SG RLL +T F E+I G ++ S+AL+AD+ HML+D AAL +A ++V+ + +K
Sbjct: 10 SGNSKRLLAAFIITATFMVAEVIGGLLSGSLALLADAGHMLTDAAALFVALVAVRFAQRK 69
Query: 65 -WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+++TFG+ R L A VNA+ L+ + I EA++RF +
Sbjct: 70 PNARHTFGYLRLTTLAAFVNALTLILITAFIFWEAIQRFYD 110
Score = 72.1 bits (169), Expect = 2e-11
Identities = 41/150 (27%), Positives = 78/150 (52%), Gaps = 6/150 (4%)
Query: 184 SDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXW 243
S+ ++N++ LHVL D LGS+ + +A+++ T W IDP W
Sbjct: 141 SEEKNINVRAAALHVLGDLLGSVGAIAAAIIILYTNWT---PIDPILSILVSCLVLRSAW 197
Query: 244 PLLRESSLILLQTVPTHIQVDAIQRRLK-NVEGVMAVHEFHVWQLAGDRIIASAHIRCRN 302
LL+ES LL+ P+ + V+A+Q+ + N+ V +H H+WQ+ G++ + + H +
Sbjct: 198 ALLKESIHELLEGTPSQLSVEALQKDVTLNIPEVRNIHHVHLWQV-GEKPMMTLHAQVVP 256
Query: 303 LSEYMKIAEKVKEF-FHNEGIHSTTIQPEF 331
++ + +++E+ + I TIQ E+
Sbjct: 257 PHDHDALLRRIQEYLLKHYQIEHATIQMEY 286
>UniRef50_Q3VS68 Cluster: Cation efflux protein; n=2;
Chlorobiaceae|Rep: Cation efflux protein -
Prosthecochloris aestuarii DSM 271
Length = 319
Score = 76.6 bits (180), Expect = 9e-13
Identities = 39/101 (38%), Positives = 66/101 (65%), Gaps = 3/101 (2%)
Query: 4 YSGKKCR--LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMS 61
+ G+K + L + +TG F VELI G+++ S+AL+AD+ HM +D+ AL I++L++++S
Sbjct: 31 FKGRKAKKGLRFAVSVTGLIFLVELIGGWVSGSLALMADAGHMATDLFALSISYLAIRLS 90
Query: 62 PK-KWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
+ K ++G+ R E++ AL+N V L IT+EA KR
Sbjct: 91 ARPSTKKRSYGYFRIEIIAALINGVILCITALFITIEAWKR 131
Score = 64.5 bits (150), Expect = 4e-09
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N+K ++H+LSD GS+ VV ++++ LT ID ++RE
Sbjct: 169 VNVKAAYIHILSDLAGSVGVVAGSILISLTRITT---IDSIISFIIAILIVQSALKIIRE 225
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
+ +L+++VP + + I+ L N V +H+ HVW L S H+ +NL
Sbjct: 226 AVDVLMESVPPELDIQEIEEALLNFRHVEGLHDLHVWALTSGVNALSCHLLVKNLDAGQN 285
Query: 309 IAEKV-KEFFHNEGIHSTTIQPE 330
I + +E I TIQ E
Sbjct: 286 ILVPIHRELKEKYNIDHVTIQLE 308
>UniRef50_A5ESK1 Cluster: Cation efflux system protein czcD; n=4;
Bradyrhizobiaceae|Rep: Cation efflux system protein czcD
- Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length = 305
Score = 76.6 bits (180), Expect = 9e-13
Identities = 41/150 (27%), Positives = 71/150 (47%), Gaps = 4/150 (2%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
S+ +N++G + VLSD LGSL V+ +AL++ T W DP
Sbjct: 146 SAGSSESLNVQGAYFEVLSDMLGSLGVIAAALIIMFTGWTLA---DPIIGAGIGLFIVPR 202
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR 301
W LL ++ IL++ VP I + +++ L+ + GV AVH+ HVW + + H+
Sbjct: 203 TWKLLNQAVHILMEGVPAEIDLPLLEKALREIPGVTAVHDLHVWTITSGTDSLTGHLVVT 262
Query: 302 NLSEYMKIAEKVKEFFHNE-GIHSTTIQPE 330
++ + ++ K + I T+Q E
Sbjct: 263 DMQAAATVLKRAKAVLEEKFKIDHVTLQIE 292
Score = 67.7 bits (158), Expect = 4e-10
Identities = 36/94 (38%), Positives = 55/94 (58%), Gaps = 1/94 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNT 69
L L LT + E++ G T S+AL+AD+ HM +D L +A ++ + K + + T
Sbjct: 24 LYAALALTLTYMTAEIVGGIWTGSLALIADAAHMATDAGGLGLALFAIHFAQKAPTPQKT 83
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
+G+ R E+L AL+NAV L+ L I EA KRF+
Sbjct: 84 YGYLRTEILAALINAVVLLLLTIYILYEAYKRFL 117
>UniRef50_A0LXC1 Cluster: CDF family cation efflux protein; n=3;
Bacteria|Rep: CDF family cation efflux protein -
Gramella forsetii (strain KT0803)
Length = 295
Score = 76.6 bits (180), Expect = 9e-13
Identities = 43/148 (29%), Positives = 75/148 (50%), Gaps = 6/148 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
MN K V H+L D LG + V+ A+V++ +K HY+DP L++
Sbjct: 141 MNEKVVSWHLLEDVLGWVAVLIVAIVLY---FKDIHYLDPALSLLITLYILYNVIIRLKD 197
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSE--- 305
+ + LQ VP I +D I+ +++ +E V ++H H+W L G+ + ++HI+ N+ E
Sbjct: 198 TLFVFLQGVPKDIDLDEIKSKIREIENVSSLHHTHLWSLEGEHHVFTSHIKLNNIKELGQ 257
Query: 306 YMKIAEKVKEFFHNEGIHSTTIQPEFVE 333
+ I EK++ + TI+ E E
Sbjct: 258 IITIKEKIRNILKDYNFDHYTIETELDE 285
Score = 56.4 bits (130), Expect = 1e-06
Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 3/103 (2%)
Query: 3 RYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIA-FLSVKMS 61
+ SGK +L L L F +E I G NS+A+++D+ H L D +L + +L K
Sbjct: 8 KQSGKNLKLAFFLNLA--FTILEFIGGMYVNSIAIISDAVHDLGDSLSLGTSWYLDKKSK 65
Query: 62 PKKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
++ +FG+ R +LGAL+N+V L+A + EAV R +E
Sbjct: 66 QGANAQFSFGYRRFSLLGALINSVVLIAGSVYVIYEAVGRILE 108
>UniRef50_Q8U3B2 Cluster: Cation efflux system protein; n=5;
cellular organisms|Rep: Cation efflux system protein -
Pyrococcus furiosus
Length = 295
Score = 76.6 bits (180), Expect = 9e-13
Identities = 40/105 (38%), Positives = 63/105 (60%), Gaps = 1/105 (0%)
Query: 8 KCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWS 66
K R++ L G VE+I G ++ S+AL +DS H SD +++ +++++K+ + K
Sbjct: 9 KRRMIISFALNMGIALVEIIGGIVSRSLALFSDSLHNFSDSMSILTSYIAIKIGEREKNE 68
Query: 67 KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
K TFG+ RAE+L A VN+ LV + + VEA KRF E I+ P
Sbjct: 69 KYTFGYKRAEILVAFVNSAILVGVALFLIVEAYKRFKTPEPINGP 113
Score = 70.5 bits (165), Expect = 6e-11
Identities = 39/147 (26%), Positives = 73/147 (49%), Gaps = 10/147 (6%)
Query: 188 HMNMKGVFLHVLSDALGSLIVV--GSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPL 245
++N++ +LH+LSD L S+ VV G A++ W W +DP + +
Sbjct: 140 NINVRSAYLHLLSDTLSSVAVVLGGIAIIKWNAIW-----VDPLLSALISIYILREAYEI 194
Query: 246 LRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN--L 303
L+ES +L++ P ++ + I+R ++++ GV H FH W++ + H+ + +
Sbjct: 195 LKESVEVLMEASP-NLDFNEIKREIESIPGVKNAHHFHAWRVGEKEVHFECHVEVNDMLI 253
Query: 304 SEYMKIAEKVKEFFHNEGIHSTTIQPE 330
SE +I + + E GI T+Q E
Sbjct: 254 SEAQQIIDVIAERLRRFGITHVTVQLE 280
>UniRef50_Q9ZT63 Cluster: Metal tolerance protein 1 (AtMTP1) (Zinc
transporter ZAT-1) (ZAT1p) [Contains: Metal tolerance
protein 1 short form]; n=31; Magnoliophyta|Rep: Metal
tolerance protein 1 (AtMTP1) (Zinc transporter ZAT-1)
(ZAT1p) [Contains: Metal tolerance protein 1 short form]
- Arabidopsis thaliana (Mouse-ear cress)
Length = 398
Score = 76.6 bits (180), Expect = 9e-13
Identities = 43/168 (25%), Positives = 86/168 (51%), Gaps = 8/168 (4%)
Query: 165 TDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYK 223
T++++ K+KTQ K + +N++G +LHVL D++ S+ +++G A++ + EWK
Sbjct: 236 TEQLLDKSKTQVAAKEKRKRN---INLQGAYLHVLGDSIQSVGVMIGGAIIWYNPEWKI- 291
Query: 224 HYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFH 283
+D ++R +L+++ P I +++ L +E V+AVHE H
Sbjct: 292 --VDLICTLAFSVIVLGTTINMIRNILEVLMESTPREIDATKLEKGLLEMEEVVAVHELH 349
Query: 284 VWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNE-GIHSTTIQPE 330
+W + +++ + H+ R ++ + KV ++ E I TIQ E
Sbjct: 350 IWAITVGKVLLACHVNIRPEADADMVLNKVIDYIRREYNISHVTIQIE 397
Score = 58.8 bits (136), Expect = 2e-07
Identities = 35/100 (35%), Positives = 58/100 (58%), Gaps = 3/100 (3%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP-K 63
S +K + +LCL F VE++ G NS+A++ D+ H+LSDVAA I+ S+ + +
Sbjct: 54 SMRKLCIAVVLCLV--FMSVEVVGGIKANSLAILTDAAHLLSDVAAFAISLFSLWAAGWE 111
Query: 64 KWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
+ T+G+ R E+LGALV+ + L + EA+ R +
Sbjct: 112 ATPRQTYGFFRIEILGALVSIQLIWLLTGILVYEAIIRIV 151
>UniRef50_UPI0000DB7E27 Cluster: PREDICTED: similar to CG31860-PA,
partial; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG31860-PA, partial - Apis mellifera
Length = 186
Score = 76.2 bits (179), Expect = 1e-12
Identities = 37/104 (35%), Positives = 64/104 (61%), Gaps = 1/104 (0%)
Query: 1 MGRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM 60
+G +S K L L + G + VE+I G++TNS+AL++D+ HM SD AL ++ ++ +
Sbjct: 64 LGAHSADKKVLSISLLIIGAYMVVEIIGGWLTNSLALLSDAGHMFSDALALALSLIAFHL 123
Query: 61 SPKKWS-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
S + + + TFG+ R E++ A VN + L+ + I EA+ RF+
Sbjct: 124 SERPVNGRQTFGYKRFEIIAAAVNGLALMVIAVMIVYEAIGRFV 167
>UniRef50_O85143 Cluster: Transport protein; n=35; Bacteria|Rep:
Transport protein - Staphylococcus aureus
Length = 326
Score = 76.2 bits (179), Expect = 1e-12
Identities = 41/159 (25%), Positives = 72/159 (45%), Gaps = 7/159 (4%)
Query: 185 DPGH-MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXW 243
D H +NM+G FLHV+ D LGS+ + +A+++W W DP W
Sbjct: 149 DTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWT---IADPIASILVSVIILKSAW 205
Query: 244 PLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI---RC 300
+ + S IL++ P+ + +D + + + +VH+ HVW ++ D S H+
Sbjct: 206 GITKSSINILMEGTPSDVDIDEVITTITKDSRIQSVHDCHVWTISNDMNALSCHVVVDHT 265
Query: 301 RNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFVEGPQDEN 339
+ E + E ++ + IH +IQ E DE+
Sbjct: 266 LTMKECELLLENIEHDLLHLNIHHMSIQLETPNHKHDES 304
Score = 64.1 bits (149), Expect = 5e-09
Identities = 35/93 (37%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK-WSKNT 69
L + G + F+E+I G + NS+AL+ D HM SD +L +A ++ + K + T
Sbjct: 23 LFISFLIIGLYMFIEIIGGLLANSLALLRDGIHMSSDTFSLGVALVAFIYAEKNATTTKT 82
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
FG+ R EVL AL N V L + I EA+ RF
Sbjct: 83 FGYKRFEVLAALFNGVTLFVISILIVFEAITRF 115
>UniRef50_A4X1A6 Cluster: Cation diffusion facilitator family
transporter; n=7; Actinobacteria (class)|Rep: Cation
diffusion facilitator family transporter - Salinispora
tropica CNB-440
Length = 307
Score = 76.2 bits (179), Expect = 1e-12
Identities = 41/154 (26%), Positives = 75/154 (48%), Gaps = 5/154 (3%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++G +L VL D S+ V+ +A+V+ LT+W Y DP + L R
Sbjct: 152 LNVRGAYLEVLGDLFTSVGVIIAAVVITLTDW---WYADPLIAVVVGLFILPRAYQLGRA 208
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
+ +L+Q P H+ + ++ + V+GV VH+ HVW L +ASAH+ +++
Sbjct: 209 ALRVLVQAAPVHLDISVVRAAMLGVDGVADVHDLHVWTLTSGMEVASAHLALERDADFAA 268
Query: 309 IAEKVKEFFHNE-GIHSTTIQPEFVEGPQDENEV 341
+ + + + T+Q E E P + ++V
Sbjct: 269 VLATSQRLLRDRFAVEHATLQAEPAE-PANADDV 301
Score = 62.5 bits (145), Expect = 2e-08
Identities = 33/84 (39%), Positives = 50/84 (59%), Gaps = 2/84 (2%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK--KWSKNTFGWARAEVL 78
F VE + +T S+AL++D+ HM +DV + +A ++ + K + + TFG R EVL
Sbjct: 32 FMVVEAVAAVMTGSLALLSDAGHMFTDVLGMGMALAAITAASKASRAGQRTFGLYRMEVL 91
Query: 79 GALVNAVFLVALCFSITVEAVKRF 102
AL NAV L + + VEAV+RF
Sbjct: 92 AALANAVLLFGVASYVVVEAVRRF 115
>UniRef50_A7HC19 Cluster: Cation diffusion facilitator family
transporter; n=4; Cystobacterineae|Rep: Cation diffusion
facilitator family transporter - Anaeromyxobacter sp.
Fw109-5
Length = 342
Score = 75.8 bits (178), Expect = 2e-12
Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 5/148 (3%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N + FLHVLSD + S+ ++G A + L ++DP L+ E
Sbjct: 187 LNARAAFLHVLSDTVSSVAILGGAGAMALRP--DLRWLDPVLSLAIAALILWGALRLIFE 244
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAH--IRCRNLSEY 306
+ IL++ VP H+ V A+ R++++ GV AVH+ H+W ++ SAH + ++
Sbjct: 245 ITDILMEGVPRHLDVAAVTRQMESAHGVSAVHDLHIWTISSGMYALSAHLVVHAESIGRN 304
Query: 307 MKIAEKVKEFFHNE-GIHSTTIQPEFVE 333
I +VK GI TT+Q E VE
Sbjct: 305 DDILNEVKHGLRRSFGIDHTTLQIESVE 332
Score = 69.3 bits (162), Expect = 1e-10
Identities = 39/102 (38%), Positives = 62/102 (60%), Gaps = 2/102 (1%)
Query: 2 GRYSGKKCR-LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM 60
G ++G R L L +TGG E I G+++ S+AL++D+ HML+D AL +A ++ +
Sbjct: 49 GHHAGASLRRLAASLAITGGVMIAEAIGGWLSGSLALLSDAAHMLTDAGALGLALVAAYL 108
Query: 61 SPKKWS-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
+ + + K T+G+ RAEVL A +N L+ L I EAV+R
Sbjct: 109 ATRPANDKRTYGYRRAEVLAAQLNVGALLVLSVWIVWEAVER 150
>UniRef50_A6SIM4 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 315
Score = 75.8 bits (178), Expect = 2e-12
Identities = 32/91 (35%), Positives = 58/91 (63%), Gaps = 2/91 (2%)
Query: 246 LRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC--RNL 303
++ + I+LQ+VP+ I ++ ++ ++N+ G++++HE H+W L + +ASAHI +L
Sbjct: 198 IKNAGAIMLQSVPSGININNVKHDIENIAGILSIHELHIWSLCQRKTVASAHIVTIETDL 257
Query: 304 SEYMKIAEKVKEFFHNEGIHSTTIQPEFVEG 334
+MK A+ ++E H GIHS T+Q E G
Sbjct: 258 KAFMKQAKLIRECLHAYGIHSVTLQAEASNG 288
Score = 58.4 bits (135), Expect = 3e-07
Identities = 27/70 (38%), Positives = 46/70 (65%), Gaps = 2/70 (2%)
Query: 45 LSDVAALIIAFLSVKMSPKKWSKN--TFGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
L+D+ ++A ++++S + S + +FGW RAE+LGA N FL+AL SI ++++ RF
Sbjct: 39 LNDLIGFMVALAALRVSQRSDSPDFLSFGWQRAELLGAFFNGCFLLALGVSIALQSIDRF 98
Query: 103 IEFEVIHNPK 112
+ E + NPK
Sbjct: 99 VYLEKVKNPK 108
>UniRef50_A7HL40 Cluster: Cation diffusion facilitator family
transporter; n=1; Fervidobacterium nodosum Rt17-B1|Rep:
Cation diffusion facilitator family transporter -
Fervidobacterium nodosum Rt17-B1
Length = 324
Score = 75.4 bits (177), Expect = 2e-12
Identities = 45/152 (29%), Positives = 79/152 (51%), Gaps = 8/152 (5%)
Query: 189 MNMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
+N+K +LH+L DA S+ +V+G+ L+ +L + IDP + +L
Sbjct: 169 INIKSAYLHMLGDAFSSVAVVLGAILIKYLNIYT----IDPILTIFIALYIGKESFEILI 224
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR---NLS 304
+S +L+Q+ P +I VD I +RL+N+ + VH H+W L G HI + +S
Sbjct: 225 KSLNVLMQSTPHNIDVDEIIKRLENISEIENVHHVHIWSLDGKTNFFEGHINLKEDVTVS 284
Query: 305 EYMKIAEKVKEFFHNEGIHSTTIQPEFVEGPQ 336
+ M I +K+++ I+ +TIQ E+ P+
Sbjct: 285 QSMVIYKKIEQELSKMEIYHSTIQFEYKGCPE 316
Score = 74.5 bits (175), Expect = 4e-12
Identities = 42/107 (39%), Positives = 66/107 (61%), Gaps = 3/107 (2%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
SGKK L ++ L G E I G + S+ALV+DS H LSD ++I+A+ + K+S +
Sbjct: 36 SGKK--LFYVVLLNFGITLAEFIGGMLAGSLALVSDSMHNLSDALSIILAYFAHKISLRG 93
Query: 65 WSK-NTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
+K TFG+ RA+++ A VN+V L+ + + EAV R I+ E +H+
Sbjct: 94 ANKGKTFGYGRAKIISAFVNSVTLMVITVLLIKEAVLRLIKPEFVHS 140
>UniRef50_A0NU32 Cluster: Cation efflux system protein; n=1; Stappia
aggregata IAM 12614|Rep: Cation efflux system protein -
Stappia aggregata IAM 12614
Length = 323
Score = 75.4 bits (177), Expect = 2e-12
Identities = 46/150 (30%), Positives = 75/150 (50%), Gaps = 7/150 (4%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
G +NM+ LHVL D LGS+ + +A+V++ T W + IDP ++
Sbjct: 178 GSLNMRSAILHVLGDLLGSVAAIAAAVVIYFTGW---YPIDPILSVFVALLIVRSAVSVM 234
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKN-VEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSE 305
R+S+ ILL+ P I D ++ L N V G++ V+ H+W LA +I A+ H + +
Sbjct: 235 RQSAHILLEGAPADIDRDTLKTDLLNAVPGLVDVYHIHLWSLAEGKINATMHATLKPEDD 294
Query: 306 YMKIAEKVKEFFHN-EGIHSTTIQPEFVEG 334
+ +++E + GI TI E EG
Sbjct: 295 AENVLRQIRERLKSRHGIGHVTI--EITEG 322
Score = 66.1 bits (154), Expect = 1e-09
Identities = 36/93 (38%), Positives = 58/93 (62%), Gaps = 1/93 (1%)
Query: 17 LTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKNTFGWARA 75
L F F EL+ G++ S+AL+AD+ HM++D A+L +A+ + + S K ++ T+G R
Sbjct: 57 LIAAFMFAELVGGWLAGSLALMADAVHMVTDAASLGLAWWAFQQSKKPADARLTYGRDRL 116
Query: 76 EVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
VL A N++FL+ + I VEA RF+E E +
Sbjct: 117 PVLIAFANSIFLLVVTGWICVEAAGRFMEPETV 149
>UniRef50_Q9PF12 Cluster: Cobalt-zinc-cadmium resistance protein;
n=26; Proteobacteria|Rep: Cobalt-zinc-cadmium resistance
protein - Xylella fastidiosa
Length = 321
Score = 74.9 bits (176), Expect = 3e-12
Identities = 42/144 (29%), Positives = 74/144 (51%), Gaps = 4/144 (2%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
+++MKG +L V SD LGS+ V+ +A+V+++T W +++DP W LL
Sbjct: 167 NLSMKGAYLEVWSDMLGSVAVIVAAIVIYVTGW---YWVDPVLAVLIGLWVLPRTWVLLG 223
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYM 307
E+ +LL+ VP ++ I+ L + GV VH+ H+W L + +AH+ +
Sbjct: 224 EAVNVLLEGVPKGFELLPIRDALSHHPGVANVHDVHLWALGSRMPLLTAHVVALQGTAPD 283
Query: 308 KIAEKVKEFFHNE-GIHSTTIQPE 330
++ ++E H I T+Q E
Sbjct: 284 RLRRMLQELLHERFSIEHVTLQIE 307
Score = 68.9 bits (161), Expect = 2e-10
Identities = 38/88 (43%), Positives = 56/88 (63%), Gaps = 1/88 (1%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNTFGWA 73
L LT F E+I +T S+AL++D+ HM +DV AL+IA ++V++S + + T+G+A
Sbjct: 43 LGLTASFLVAEIIGAVLTRSLALLSDAVHMATDVFALMIALVAVRLSRRPPDVRRTYGYA 102
Query: 74 RAEVLGALVNAVFLVALCFSITVEAVKR 101
R E GALVN V L + I EAV+R
Sbjct: 103 RLEAFGALVNGVLLFGVGGYILWEAVQR 130
>UniRef50_Q8CNH2 Cluster: CzrB protein; n=3; Staphylococcus|Rep:
CzrB protein - Staphylococcus epidermidis (strain ATCC
12228)
Length = 323
Score = 74.9 bits (176), Expect = 3e-12
Identities = 36/85 (42%), Positives = 57/85 (67%), Gaps = 1/85 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLG 79
F VE+I G++ NS+AL++D FHMLSD +L +A ++ + K +K+ T+G+ R E+L
Sbjct: 41 FMLVEIIGGFLANSLALLSDGFHMLSDAISLGVALIAFIYAEKHATKSKTYGYKRFEILA 100
Query: 80 ALVNAVFLVALCFSITVEAVKRFIE 104
AL N V L + I +EA++RF+E
Sbjct: 101 ALFNGVTLFIISIIIIIEAIRRFLE 125
Score = 62.1 bits (144), Expect = 2e-08
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 13/162 (8%)
Query: 185 DPGH-MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXW 243
D H +NM+G FLHVL D GS+ + ++L++W + DP +
Sbjct: 157 DTSHNLNMRGAFLHVLGDLFGSVGAIVASLLIWGFNFT---IADPIASILVSLIILKSAY 213
Query: 244 PLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNL 303
+ + S IL++ P I ++A+ + + E + VH+ HVW ++ D S H +
Sbjct: 214 GISKSSLNILMEGTPNDIDLNAVIKAISKDERIQNVHDCHVWTISNDMNALSCH---AVV 270
Query: 304 SEYMKI--AEKVKEFFHNE----GIHSTTIQPEFVEGPQDEN 339
EY+ + E + + ++ I TIQ E E DE+
Sbjct: 271 PEYLSVQTCETMLKSIESDLLQLNIQHMTIQLETPEHKHDES 312
>UniRef50_Q2LY02 Cluster: Cobalt-zinc-cadmium resistance protein;
n=1; Syntrophus aciditrophicus SB|Rep:
Cobalt-zinc-cadmium resistance protein - Syntrophus
aciditrophicus (strain SB)
Length = 323
Score = 74.9 bits (176), Expect = 3e-12
Identities = 47/146 (32%), Positives = 76/146 (52%), Gaps = 6/146 (4%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++N++ FLH+L+DAL SL VV ++WL Y+ +D W +L+
Sbjct: 161 NINIRSSFLHMLTDALTSLGVVVLG-IIWLYRPWYR--LDTLVSWGIVALIFYGGWGILK 217
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC--RNLSE 305
E+ IL+ P I V I+R ++ +EG+ +H HVW L+ DR +AHI + LS+
Sbjct: 218 ETYQILMNATPPGISVKEIKRAVEAIEGIREIHHIHVWTLSPDRAALAAHIIVDDQMLSQ 277
Query: 306 YMKIAEKVKEFFHNE-GIHSTTIQPE 330
+ +V+E + GI T+Q E
Sbjct: 278 VDLLVSRVRELLWSRFGIDHPTLQFE 303
Score = 66.5 bits (155), Expect = 1e-09
Identities = 36/100 (36%), Positives = 60/100 (60%), Gaps = 1/100 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KN 68
RLL + L V++I G + SMAL++D+ H LSD +L+I++++++M ++ +
Sbjct: 32 RLLMTMMLNLVIPVVQIIGGILAGSMALISDALHNLSDFTSLLISYVALRMGERQPTVSQ 91
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
TFG+ R EVL ALVN L + I +E +R + +VI
Sbjct: 92 TFGYKRIEVLAALVNVSLLYGVAIFIAIEGWQRLLAPQVI 131
>UniRef50_A3XRG5 Cluster: Cobalt/zinc/cadmium cation efflux pump
protein; n=7; Bacteria|Rep: Cobalt/zinc/cadmium cation
efflux pump protein - Leeuwenhoekiella blandensis MED217
Length = 304
Score = 74.9 bits (176), Expect = 3e-12
Identities = 38/148 (25%), Positives = 77/148 (52%), Gaps = 6/148 (4%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
G+MNM+ +LH+L+D + S+ V+ ++++ + ++ID + LL
Sbjct: 148 GNMNMRSAYLHLLTDMMASVAVLVGGILMYFFKI---YWIDSLLTLAISIYLIVMGYGLL 204
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN---L 303
+ S +L+ P +++D + + +K ++ + +H H+WQL D + AHI +N L
Sbjct: 205 KSSFKVLMLFSPEDLEIDDLIKEVKQLDAIKNIHHIHIWQLNDDEVHLEAHIDLKNDIKL 264
Query: 304 SEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
S + I +++ + GI+ IQPE+
Sbjct: 265 SAFDAILLEIEHIAMHYGINHINIQPEY 292
Score = 70.5 bits (165), Expect = 6e-11
Identities = 35/85 (41%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLGALVN 83
++I G I+ S+AL++D+ H LSDV +LII++++ + S K+ S + TFG+ RAE++ A VN
Sbjct: 35 QIIGGLISGSLALLSDAVHNLSDVISLIISYIAQRYSKKEASTHKTFGYKRAEIIAAFVN 94
Query: 84 AVFLVALCFSITVEAVKRFIEFEVI 108
A L+ + + EAV+RF+ + I
Sbjct: 95 AATLIVIAVLLMKEAVERFLNPQAI 119
>UniRef50_Q4T2L9 Cluster: Chromosome undetermined SCAF10234, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF10234, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 401
Score = 74.5 bits (175), Expect = 4e-12
Identities = 40/105 (38%), Positives = 59/105 (56%), Gaps = 5/105 (4%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-- 68
L LCL F FVEL G +NS+ L++DSFHM D AL+ + +S +W N
Sbjct: 38 LFFFLCLNLSFAFVELTYGIWSNSLGLISDSFHMFFDCTALLAGLAASVIS--RWRSNDS 95
Query: 69 -TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
++G+ RAEVL VN +FL+ F I E ++R +E +H+ +
Sbjct: 96 FSYGYVRAEVLAGFVNGLFLIFTAFFIMSEGIERALEPPDVHHER 140
Score = 58.0 bits (134), Expect = 3e-07
Identities = 43/144 (29%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Query: 191 MKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYI-DPXXXXXXXXXXXXXXWPLLRES 249
++GV LH+++D LGS+ V+ SAL++ KY I DP PLL+ES
Sbjct: 259 LQGVLLHIMADTLGSVGVIISALLM----QKYDLMIADPICSMLIALLIAVSVIPLLKES 314
Query: 250 SLILLQTVP---THIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEY 306
IL+Q P H D Q R+++++GV ++ E H W L D I + + ++
Sbjct: 315 IGILMQRTPPSLDHALPDCYQ-RVQHLQGVYSLQEPHFWTLCSDVYIGTVKLLVAPDADS 373
Query: 307 MKIAEKVKEFFHNEGIHSTTIQPE 330
I + F G+ +Q E
Sbjct: 374 RWILSQTHHIFTQAGVRQLYVQME 397
>UniRef50_Q8ERA7 Cluster: Cation efflux system permease; n=14;
Bacillaceae|Rep: Cation efflux system permease -
Oceanobacillus iheyensis
Length = 300
Score = 74.1 bits (174), Expect = 5e-12
Identities = 35/85 (41%), Positives = 56/85 (65%), Gaps = 1/85 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLG 79
F +E + G +TNS+AL++D+ HMLSD AAL + L+ + K + N TFG+ R E++
Sbjct: 29 FMIMEAVGGILTNSLALLSDAGHMLSDAAALGLTLLAFNIGEKSITANKTFGYKRFEIIA 88
Query: 80 ALVNAVFLVALCFSITVEAVKRFIE 104
A +N V L+ + I +EA++RF+E
Sbjct: 89 AFINGVTLILISIFIFIEALRRFVE 113
Score = 67.3 bits (157), Expect = 6e-10
Identities = 37/144 (25%), Positives = 69/144 (47%), Gaps = 4/144 (2%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++N+K LHV+ D LGS+ + + ++ L W + DP + +
Sbjct: 147 NLNLKSALLHVMGDLLGSIGALVAGALILLFNW---NIADPIASIIVAILIIISGIRITK 203
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYM 307
+S IL++ PT++ +D ++R L ++ GV VH+ HVW + + S HI+ +
Sbjct: 204 DSLHILMEGKPTNVNIDEMKRSLLSLSGVQDVHDLHVWSITSEFPSMSCHIQVTEQTNRD 263
Query: 308 KIAEKVKEFFHNE-GIHSTTIQPE 330
++ E+ + + I TIQ E
Sbjct: 264 QLLEEATKILQDSFSISHCTIQME 287
>UniRef50_Q5NP70 Cluster: Cation efflux system protein; n=2;
Zymomonas mobilis|Rep: Cation efflux system protein -
Zymomonas mobilis
Length = 322
Score = 74.1 bits (174), Expect = 5e-12
Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 5/114 (4%)
Query: 187 GH--MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWP 244
GH +N FLH+L DAL S +VV S ++ +T W H+IDP W
Sbjct: 169 GHEELNRHAAFLHMLLDALVSAVVVLSGFIIKMTGW---HWIDPSLSLAIVVVLLWSSWS 225
Query: 245 LLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
L++ S + L VP I V A+ RL + V+ VH H+W ++ +AHI
Sbjct: 226 LIKRSFAMALNAVPPSIDVSAVVTRLDQLPDVINVHHVHIWPVSTSETAMTAHI 279
Score = 62.9 bits (146), Expect = 1e-08
Identities = 33/85 (38%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLS-VKMSPKKWSKNTFGWARAEVLG 79
F VE+ G + S++L+AD+ H LSDV L ++ + + K S+ T+G+ + +L
Sbjct: 55 FILVEIGYGITSGSLSLIADAGHNLSDVLGLALSLAAFIAERSKPTSRFTYGYRSSSILA 114
Query: 80 ALVNAVFLVALCFSITVEAVKRFIE 104
AL NA+FLV C +I EA++RF E
Sbjct: 115 ALFNALFLVIACGAIGWEAIRRFSE 139
>UniRef50_Q74FW5 Cluster: Cation efflux family protein; n=7;
Desulfuromonadales|Rep: Cation efflux family protein -
Geobacter sulfurreducens
Length = 331
Score = 73.3 bits (172), Expect = 9e-12
Identities = 42/153 (27%), Positives = 76/153 (49%), Gaps = 9/153 (5%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++ FLHV+ DA S+ V+ L+++ T W + +D W +LRE
Sbjct: 144 LNVRSAFLHVVGDAAASVGVIVGGLIMYFTGW---YVLDALISIGIGCVIFAGSWRVLRE 200
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAH--IRCRNLSEY 306
++ ILL+ VP + + + VEGV AVH+ ++W + + SAH ++ +
Sbjct: 201 AAHILLEGVPRGMSTQQVANEMAGVEGVNAVHQMNIWTICSHILALSAHVDVKPEYKGQQ 260
Query: 307 MKIAEKVKE-FFHNEGIHSTTIQPE---FVEGP 335
++ ++++ F I TT+Q E V+GP
Sbjct: 261 AEVLRQIEQLLFERYHITHTTLQAECTRCVDGP 293
Score = 62.9 bits (146), Expect = 1e-08
Identities = 33/100 (33%), Positives = 55/100 (55%), Gaps = 1/100 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KN 68
RL + LT E++ G TNS+AL++D+ H+ D+ AL+++ ++K++ S
Sbjct: 14 RLKYAIALTALTLVAEIVGGIWTNSLALLSDAAHVFLDLFALVLSLAAIKLASYPASDTK 73
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
TFGW RAEV + +N + + I EAV R + E +
Sbjct: 74 TFGWHRAEVFASFINGATVFLMALGIFYEAVGRLMNPEAV 113
>UniRef50_Q1II24 Cluster: Cation diffusion facilitator family
transporter; n=1; Acidobacteria bacterium Ellin345|Rep:
Cation diffusion facilitator family transporter -
Acidobacteria bacterium (strain Ellin345)
Length = 312
Score = 73.3 bits (172), Expect = 9e-12
Identities = 46/145 (31%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++ FLH L D L + V+ V+ T + ++DP + ++R+
Sbjct: 146 LNIRSAFLHELGDTLSTAAVIVGGWVILETG---QSWVDPALSFGIGVLVLWSSFGVIRD 202
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNL--SEY 306
S ILL+ P + V + R+ +++GV+ VH+ HVW L + S HIR +L SE
Sbjct: 203 SLNILLEGTPRGMNVQRLAERMCSIDGVIDVHDLHVWSLGSETHALSCHIRIADLRASES 262
Query: 307 MKIAEKVKE-FFHNEGIHSTTIQPE 330
I + V E H+ IH TTIQ E
Sbjct: 263 EAILKAVNEAVAHDFHIHHTTIQFE 287
Score = 54.0 bits (124), Expect = 6e-06
Identities = 29/77 (37%), Positives = 50/77 (64%), Gaps = 1/77 (1%)
Query: 26 LIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLGALVNA 84
+++G ++S+AL++++ H LSD AL++ +++V + + S TFG+ RA VL A +NA
Sbjct: 33 VVMGIRSHSLALLSEAGHNLSDFLALLLTWVAVYVQSRPPSATKTFGYQRAGVLAAFINA 92
Query: 85 VFLVALCFSITVEAVKR 101
LV + F I EA +R
Sbjct: 93 ASLVLIAFFIFYEAGRR 109
>UniRef50_Q6A8D8 Cluster: Cation-efflux transport protein; n=2;
Actinomycetales|Rep: Cation-efflux transport protein -
Propionibacterium acnes
Length = 303
Score = 72.9 bits (171), Expect = 1e-11
Identities = 34/94 (36%), Positives = 59/94 (62%), Gaps = 1/94 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-T 69
L+ L L F E+I I+ S+AL++D+ HMLSD+ A+ IA + +++ ++ + T
Sbjct: 19 LVAALTLLAAFMITEIITAVISGSLALLSDAGHMLSDIGAIAIALWAARLTRRRPQGSWT 78
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
+GW RAE++ A VN V L+ + + +EAV+R +
Sbjct: 79 WGWKRAEIMSAAVNGVTLLVVAILVGIEAVRRLV 112
Score = 62.5 bits (145), Expect = 2e-08
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++G + H+L+D G + + + LV+ T W D W LL +
Sbjct: 148 LNVEGAYQHILTDLFGFIGTLVAGLVIVTTGWTRA---DAIASLIICGLMLRAAWSLLSQ 204
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ IL++ P + +D ++ L +++ V +VH+ H W ++ D SAHI
Sbjct: 205 TGRILMEVAPASLDLDEVRHHLMDLDHVRSVHDLHAWTVSSDLPALSAHI 254
>UniRef50_Q64SU7 Cluster: Cation efflux system protein; n=5;
Bacteroidetes|Rep: Cation efflux system protein -
Bacteroides fragilis
Length = 302
Score = 72.9 bits (171), Expect = 1e-11
Identities = 41/143 (28%), Positives = 67/143 (46%), Gaps = 3/143 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N+KG +LH+ +D L S+ VV S +++ T W +DP W LL +
Sbjct: 151 LNVKGAYLHMAADTLVSVGVVISGIIIMYTGWTL---VDPIIGLVIAVIIVISTWSLLHD 207
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
S + L VP I + I R + GV + H H+W L+ +AHI +L +
Sbjct: 208 SLRLSLDGVPLGIDSEKIGRVILEQPGVESYHHLHIWALSTTETALTAHIVIGDLRRMEE 267
Query: 309 IAEKVKEFFHNEGIHSTTIQPEF 331
+ +VK + GI T++ E+
Sbjct: 268 VKREVKHELEHVGITHATLEFEY 290
Score = 54.0 bits (124), Expect = 6e-06
Identities = 27/82 (32%), Positives = 53/82 (64%), Gaps = 1/82 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP-KKWSKNTFGWARAEVLG 79
F VE +G+ +S+ L++D+ H L DVA+L++A L+ +++ S+ T+G+ ++ VL
Sbjct: 32 FVLVEFGIGFYYDSLGLLSDAGHNLGDVASLVLAMLAFRLAKVHPNSRYTYGYKKSTVLV 91
Query: 80 ALVNAVFLVALCFSITVEAVKR 101
+L+NAV L+ I E++++
Sbjct: 92 SLLNAVILLVAVGIIITESIEK 113
>UniRef50_A2SD15 Cluster: Cation efflux system protein; n=1;
Methylibium petroleiphilum PM1|Rep: Cation efflux system
protein - Methylibium petroleiphilum (strain PM1)
Length = 353
Score = 72.9 bits (171), Expect = 1e-11
Identities = 67/273 (24%), Positives = 118/273 (43%), Gaps = 28/273 (10%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN---TFGWARAEVLGAL 81
E+ G+ +SMAL+AD +HM + AA+ +A LS ++ ++W+ + + G + EVLGA
Sbjct: 40 EIAAGWWWHSMALLADGWHMGTHAAAIGVAALSYALA-RRWAGDARFSLGPWKVEVLGAY 98
Query: 82 VNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXXXXX----HVPPP 137
+AV L + I VE+ R E + + H P P
Sbjct: 99 TSAVLLGVVAIGIAVESGLRLWAPEPVAYDESLVVAAIGLAVNAVCAKLLHGGHDHAPGP 158
Query: 138 SNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLH 197
+ H H D+ + Q H +++D +N++ +LH
Sbjct: 159 GHTGH-------------DHGHHDHHAHHAHAVEHTGQEH--AHAATDGKDLNLRAAYLH 203
Query: 198 VLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTV 257
VL+DA S++ +G+ L W ++DP + LLR++S ILL
Sbjct: 204 VLADAATSVLAIGALLAGKYAGWV---WVDPLVGLLGAALIAVWSFGLLRQTSTILLDRE 260
Query: 258 PTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGD 290
H ++ +L++ +G V + H+W++ GD
Sbjct: 261 MDHPLAHQVREQLES-DGDARVADLHLWRV-GD 291
>UniRef50_Q22DR5 Cluster: Cation diffusion facilitator family
transporter containing protein; n=1; Tetrahymena
thermophila SB210|Rep: Cation diffusion facilitator
family transporter containing protein - Tetrahymena
thermophila SB210
Length = 795
Score = 72.5 bits (170), Expect = 2e-11
Identities = 48/191 (25%), Positives = 93/191 (48%), Gaps = 10/191 (5%)
Query: 157 HNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVW 216
H+ + E D +H S + + N+ GVFLH+L+DALGS+ V+ S+++++
Sbjct: 571 HDHNHDHEHDHNHNHDHGHDHGHSHSHGEGHNENLTGVFLHILADALGSVGVIISSILIY 630
Query: 217 LTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQ---TVPTHIQVDAIQRRLKNV 273
W + DP +PLL+ S LLQ H+Q++ I ++L
Sbjct: 631 YYGW---YISDPITSCIISIFIFISVFPLLKGSFTTLLQGYNIKKYHVQLEEIIQKLSGH 687
Query: 274 EGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHN-EGIHSTTIQPEFV 332
+ + E H+W + ++ + + R++ + K+ ++VK+ ++ + I TI E +
Sbjct: 688 QDIERYSEIHLWAYTSNNLVFTVKVHIRDIRKRFKVLKEVKKILNSYKNIKYQTI--EII 745
Query: 333 EGPQDE-NEVS 342
Q+E +E+S
Sbjct: 746 CDKQEELSEIS 756
Score = 59.3 bits (137), Expect = 1e-07
Identities = 30/78 (38%), Positives = 48/78 (61%), Gaps = 1/78 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLGALVN 83
+LI G ++NS++L++DS HML D +AL I + MS K S +FG+ R L +N
Sbjct: 349 KLIYGLLSNSLSLISDSAHMLFDSSALAIGLYASFMSKLKPSPTYSFGFERFSTLSGFIN 408
Query: 84 AVFLVALCFSITVEAVKR 101
+FL+ + F I E+++R
Sbjct: 409 GLFLIVVAFDIFTESIER 426
>UniRef50_A6R777 Cluster: Predicted protein; n=2;
Pezizomycotina|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 157
Score = 72.5 bits (170), Expect = 2e-11
Identities = 39/103 (37%), Positives = 62/103 (60%), Gaps = 12/103 (11%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNT 69
RL ++ ++ FF VE+ VG+ T S+ALVAD+FH +S+ ++L T
Sbjct: 11 RLSIIIAISFTFFVVEISVGFYTRSLALVADAFHYVSENPDATPSYL------------T 58
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
FGW R+ +LGA N VFL+AL SI +++++RF+ E + P+
Sbjct: 59 FGWQRSTLLGAFFNGVFLLALGVSIILQSIERFVSLERVEKPE 101
>UniRef50_Q9LXS1 Cluster: Metal tolerance protein A2; n=17;
rosids|Rep: Metal tolerance protein A2 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 378
Score = 72.5 bits (170), Expect = 2e-11
Identities = 37/145 (25%), Positives = 77/145 (53%), Gaps = 5/145 (3%)
Query: 188 HMNMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
++N++G +LHVL D++ S+ +++G A++ + EWK +D +L
Sbjct: 235 NVNIQGAYLHVLGDSIQSVGVMIGGAIIWYKPEWKI---LDLICTLVFSVIVLGTTIGML 291
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEY 306
R +L+++ P I +++ + +E V+AVHE H+W + +++ + H++ R +E
Sbjct: 292 RNILEVLMESTPREIDPTMLEKGVCEIEEVVAVHELHIWAITVGKLLLACHVKIRPEAEA 351
Query: 307 MKIAEKVKEFFHNE-GIHSTTIQPE 330
+ +K+ ++ E I TIQ E
Sbjct: 352 DMVLDKIIDYIKREHNISHVTIQIE 376
Score = 58.4 bits (135), Expect = 3e-07
Identities = 34/93 (36%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KN 68
+LL + L F VE++ G NS+A++ D+ H+LSDVAA I+ S+ S K + +
Sbjct: 58 KLLIAVLLCAIFIVVEVVGGIKANSLAILTDAAHLLSDVAAFAISLFSLWASGWKANPQQ 117
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
++G+ R E+LGALV+ + L + EA+ R
Sbjct: 118 SYGFFRIEILGALVSIQMIWLLAGILVYEAIVR 150
>UniRef50_Q0ICB8 Cluster: Cation efflux system protein; n=2;
Synechococcus|Rep: Cation efflux system protein -
Synechococcus sp. (strain CC9311)
Length = 289
Score = 72.1 bits (169), Expect = 2e-11
Identities = 47/162 (29%), Positives = 79/162 (48%), Gaps = 8/162 (4%)
Query: 176 NHKSCKSSSDPGH-MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXX 234
N S K D H +N KG +H+LSDA S V+ S L+V T W +++DP
Sbjct: 127 NLGSAKLFGDHDHDLNRKGAVVHLLSDAAVSAAVLLSTLLVGATGW---YWLDPLTGLLV 183
Query: 235 XXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIA 294
LL ++ + +P +I ++ ++ L+N++GV ++H H+W L+ R+
Sbjct: 184 GCSIGWMGIGLLGKALAETMDAIPDYIDINKVKSTLQNIKGVESIHHLHIWPLSTSRVAL 243
Query: 295 SAHIRCRNLSEY---MKIAEKVKEFFHNEGIHSTTIQPEFVE 333
+AHI R+LS+ + ++ GI T Q E V+
Sbjct: 244 TAHI-VRSLSQSEADHNLISTASSKMNSLGIDHCTFQVESVD 284
Score = 46.4 bits (105), Expect = 0.001
Identities = 25/89 (28%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNTFGWA 73
+ L G ++++VG S+AL+ D+ H DV LI+ + + + + S+ ++G
Sbjct: 17 ITLNAGLSGLQIVVGITFGSIALIGDAIHNFGDVIGLIMGWGAETLGHRAPTSRFSYGLG 76
Query: 74 RAEVLGALVNAVFLVALCFSITVEAVKRF 102
R+ L A+ NAV ++ + VE+ +RF
Sbjct: 77 RSTQLAAVANAVLILMASAVLCVESFQRF 105
>UniRef50_Q1Q6G6 Cluster: Strongly similar to cation (Co/Zn/Cd)
diffusion facilitator family protein; n=1; Candidatus
Kuenenia stuttgartiensis|Rep: Strongly similar to cation
(Co/Zn/Cd) diffusion facilitator family protein -
Candidatus Kuenenia stuttgartiensis
Length = 302
Score = 71.7 bits (168), Expect = 3e-11
Identities = 37/93 (39%), Positives = 59/93 (63%), Gaps = 1/93 (1%)
Query: 17 LTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNTFGWARA 75
+TG F VE+I G ITNS+AL++D+ HML+ + AL+I+ ++ + K + T+G+ R
Sbjct: 5 ITGVIFIVEVIGGIITNSLALLSDAGHMLTHLFALLISLFAIMFASKPPTQRKTYGFYRL 64
Query: 76 EVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
E+L AL+N + L+ + I EA RF+ E I
Sbjct: 65 EILAALLNGIILLLITVWIFYEAYHRFVTPEAI 97
Score = 71.3 bits (167), Expect = 3e-11
Identities = 36/122 (29%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 183 SSDPGH-MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
S + GH +N+K FLH+L D + S+ V+ A++++ T W + IDP
Sbjct: 122 SGEHGHSLNVKSAFLHMLGDTISSVGVIIGAVIIYYTNW---YIIDPIISIMLCILILIW 178
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR 301
+ L+ ES ILL+ P I V + +L+ + GV H+ H+W + S HI +
Sbjct: 179 SYKLIMESVDILLEATPKDINVGEVISQLEQITGVDGAHDIHIWTITSGMYAMSVHIDTK 238
Query: 302 NL 303
++
Sbjct: 239 DM 240
>UniRef50_Q0AGJ2 Cluster: Cation diffusion facilitator family
transporter; n=1; Nitrosomonas eutropha C91|Rep: Cation
diffusion facilitator family transporter - Nitrosomonas
eutropha (strain C71)
Length = 318
Score = 71.7 bits (168), Expect = 3e-11
Identities = 37/98 (37%), Positives = 62/98 (63%), Gaps = 1/98 (1%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
+G + R+ + T G+ ++ I G+++ S+AL+ADS HM+SD AAL++A ++ +++ K
Sbjct: 34 AGNERRIRFVFFFTAGYALIQAIGGWLSGSLALIADSGHMISDAAALLLALVAYRIARKP 93
Query: 65 W-SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
S T+G+ R VL AL N V L+ L I +EA+ R
Sbjct: 94 ADSTRTYGFHRVRVLAALANGVTLLLLVVWIILEAIGR 131
Score = 64.9 bits (151), Expect = 3e-09
Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 3/109 (2%)
Query: 190 NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRES 249
N++G LH++ D LGS+ V +A+ + T W +DP W L+++S
Sbjct: 170 NLRGALLHIIGDLLGSVGAVAAAVGIMFTGWTI---LDPILSVLVALLIIRSAWVLVKDS 226
Query: 250 SLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+LLQ VP + ++ L + + FH W LA + IA+ H+
Sbjct: 227 VHVLLQVVPRGMDTRVVENGLTQLPEIEEAGHFHAWILADETTIATVHV 275
>UniRef50_A3VSL3 Cluster: Cation efflux protein; n=1; Parvularcula
bermudensis HTCC2503|Rep: Cation efflux protein -
Parvularcula bermudensis HTCC2503
Length = 339
Score = 70.9 bits (166), Expect = 5e-11
Identities = 41/143 (28%), Positives = 70/143 (48%), Gaps = 4/143 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+NM+G LHV+ D LGS+ + SA+++ T W +D + L++E
Sbjct: 158 VNMRGAVLHVIGDLLGSVAAIVSAIIILFTGWV---VVDVLVTLLVCGLIARSAYALVKE 214
Query: 249 SSLILLQTVPTHIQVDAIQRRL-KNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYM 307
+ ++LL+ P I ++ + ++V GV VH +W L A+ H+R R+ +
Sbjct: 215 TGVVLLEGAPQEIDPTDLRDVIRRDVRGVTDVHNVRLWMLTPGANQATMHVRVRDPYQGD 274
Query: 308 KIAEKVKEFFHNEGIHSTTIQPE 330
+I E +K GI +TIQ E
Sbjct: 275 RILEDIKSLLAARGILDSTIQIE 297
Score = 54.8 bits (126), Expect = 3e-06
Identities = 34/96 (35%), Positives = 54/96 (56%), Gaps = 1/96 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KN 68
RL L + F VE++ G ++ S+AL+AD+ HM++D AL +A + ++ + S +
Sbjct: 29 RLRIALAIIVLFAAVEIVGGVLSGSLALLADAGHMVTDAVALALALGAKYLAQRPASDRF 88
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
FG R +VL A +N V L L + VE+V R E
Sbjct: 89 NFGHQRTQVLAAFLNGVGLFLLIAYLLVESVHRMAE 124
>UniRef50_A0JRX0 Cluster: Cation diffusion facilitator family
transporter; n=5; Actinomycetales|Rep: Cation diffusion
facilitator family transporter - Arthrobacter sp.
(strain FB24)
Length = 308
Score = 70.9 bits (166), Expect = 5e-11
Identities = 38/93 (40%), Positives = 60/93 (64%), Gaps = 1/93 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KN 68
RL+ +L +T +++I I+ S+AL+AD+ HMLSD A + IA L+ ++ + S +
Sbjct: 22 RLIAVLGITLAVVLIQIIGAVISGSLALLADAGHMLSDAAGVFIALLAAWIATRPASDQR 81
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
T+G+ RAEVL AL NA+ L+ + I EAV+R
Sbjct: 82 TYGYQRAEVLAALANALVLIVISVLIFTEAVRR 114
Score = 70.5 bits (165), Expect = 6e-11
Identities = 34/116 (29%), Positives = 61/116 (52%), Gaps = 3/116 (2%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
S+ +N++G +L VL D LGS V+ +A+V+ +T ++ D
Sbjct: 146 SAQKESLNVRGAYLEVLGDLLGSFAVIAAAVVIMVTGFQAA---DTIASMVIAVMILPRA 202
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
W LLR+ +LL+ P ++V I+ + +V GV++VH+ H+W + + SAH+
Sbjct: 203 WHLLRDVVDVLLEATPKGVEVQMIREHILSVHGVVSVHDIHIWTITSGVPVFSAHV 258
>UniRef50_Q22GX2 Cluster: Cation diffusion facilitator family
transporter containing protein; n=1; Tetrahymena
thermophila SB210|Rep: Cation diffusion facilitator
family transporter containing protein - Tetrahymena
thermophila SB210
Length = 352
Score = 70.9 bits (166), Expect = 5e-11
Identities = 31/95 (32%), Positives = 61/95 (64%), Gaps = 1/95 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP-KKWSKNT 69
L + C++ F +E + GY++NS+A++ D+ H+LSDV ++ L++ +S K S T
Sbjct: 46 LKIVCCISTSFMCIEFVGGYLSNSLAIMTDAVHLLSDVVGFLVTILAIYISRLKANSTMT 105
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+G+ RAE++GA+++ + + L + VE ++RF +
Sbjct: 106 YGYHRAEIIGAMISILIIWVLIAWMFVEGIERFFK 140
Score = 66.1 bits (154), Expect = 1e-09
Identities = 45/171 (26%), Positives = 80/171 (46%), Gaps = 4/171 (2%)
Query: 160 TDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTE 219
T E E +K + + S K + +M+M+ +H+L D + S V+ AL V+
Sbjct: 169 TKLETVTEESQKEELLSEFSIKQDVEKENMSMRAAQIHILGDTIQSAGVIIGALFVFFGG 228
Query: 220 WKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAV 279
Y DP P++++S +L++ P I+ + ++ +L+ V GV+ V
Sbjct: 229 EDY-FIADPIITIVFTIVVTFTTLPVMKDSIKVLMEGQPDDIKYETVKEKLEKVSGVVNV 287
Query: 280 HEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPE 330
H+ HVW + + +AHI + S + A K+ + GI +TIQ E
Sbjct: 288 HDLHVWSINPGFVSLTAHICSKTPSVTLFEATKLCK---KLGIVHSTIQVE 335
>UniRef50_A5E801 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 672
Score = 70.9 bits (166), Expect = 5e-11
Identities = 65/275 (23%), Positives = 113/275 (41%), Gaps = 14/275 (5%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK---WSKNTFG 71
L L F ++ + + + S+ L++DS HML D +L + ++ +S K K FG
Sbjct: 336 LLLNASFMVIQFLYSFRSKSLGLLSDSLHMLLDCLSLALGLVAGVLSKTKVDPHGKYPFG 395
Query: 72 WARAEVLGALVNAVFLVALCFSITVEAVKRF---IEFEVIHNPKXXXXXXXXXXXXXXXX 128
W E L N L+ + SI EA+ R IE + +
Sbjct: 396 WQNLENLAGFANGTLLMGISGSILFEALGRLAHPIELQKTNELIVVSVLGLLVNMVGIFA 455
Query: 129 XXXXHVPPPSN-VRHLTEIVNSNA-DRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDP 186
H + H +S++ + H+ + + + ++ ++A + K D
Sbjct: 456 FNHGHGHGHGDGSGHSHSHGHSHSHSHSHSHSHSHSHSSPQLSEQAHGEGMKDNGKEGDG 515
Query: 187 GHM--NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWP 244
+ NM+G+FLH+L+DALGS+ VV S ++ L W+ DP P
Sbjct: 516 EEVNDNMRGIFLHILADALGSVGVVISTILTKLFHWQ---GFDPIASIIIGTVIFLSAVP 572
Query: 245 LLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAV 279
L++ S+ LL +V + Q I+ L + V
Sbjct: 573 LIKSSASTLLLSV-SKSQEATIRNTLNEITSTKGV 606
>UniRef50_Q8IWU4 Cluster: Zinc transporter 8; n=18; Tetrapoda|Rep:
Zinc transporter 8 - Homo sapiens (Human)
Length = 369
Score = 70.9 bits (166), Expect = 5e-11
Identities = 42/165 (25%), Positives = 84/165 (50%), Gaps = 11/165 (6%)
Query: 176 NHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXX 235
NHK ++++ +++ F+H L D S+ V+ SAL+++ +YK DP
Sbjct: 204 NHKEVQANA-----SVRAAFVHALGDLFQSISVLISALIIYFKP-EYK-IADPICTFIFS 256
Query: 236 XXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIAS 295
+L++ S++L++ VP + ++ + V+GV++VH H+W L +++I S
Sbjct: 257 ILVLASTITILKDFSILLMEGVPKSLNYSGVKELILAVDGVLSVHSLHIWSLTMNQVILS 316
Query: 296 AHIRCRNLSEYMKIAEKV-KEFFHNEGIHSTTIQPEFVEGPQDEN 339
AH+ + + ++ K + +HS TIQ +E P D++
Sbjct: 317 AHVATAASRDSQVVRREIAKALSKSFTMHSLTIQ---MESPVDQD 358
Score = 60.5 bits (140), Expect = 6e-08
Identities = 32/101 (31%), Positives = 58/101 (57%), Gaps = 1/101 (0%)
Query: 4 YSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK 63
Y+ K +L + F E++ G+I S+A+V D+ H+L D+ + +++ S+ +S K
Sbjct: 67 YAYAKWKLCSASAICFIFMIAEVVGGHIAGSLAVVTDAAHLLIDLTSFLLSLFSLWLSSK 126
Query: 64 KWSKN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
SK TFGW RAE+LGAL++ + + + + A +R +
Sbjct: 127 PPSKRLTFGWHRAEILGALLSILCIWVVTGVLVYLACERLL 167
>UniRef50_Q8KBG3 Cluster: Cation efflux family protein; n=5;
Chlorobiaceae|Rep: Cation efflux family protein -
Chlorobium tepidum
Length = 307
Score = 70.5 bits (165), Expect = 6e-11
Identities = 43/146 (29%), Positives = 71/146 (48%), Gaps = 6/146 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
MN + + LH+L D LG L V+ ++V+ T +DP LR
Sbjct: 152 MNARVIALHLLEDVLGWLSVLLVSVVLLFTSLPI---LDPLLAIVITLYILTGVVKNLRA 208
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAH--IRCR-NLSE 305
+ LQ VP+ + +D + ++ E V VH H+W L G R + +AH I C N +E
Sbjct: 209 MVPVFLQAVPSELSLDKVVADIQQTEHVTGVHHAHLWSLDGQRTVFTAHLEIGCDVNPAE 268
Query: 306 YMKIAEKVKEFFHNEGIHSTTIQPEF 331
Y I E++++ GI+ +T++ E+
Sbjct: 269 YASIKEEIRKLVARHGIYHSTVELEY 294
Score = 56.8 bits (131), Expect = 8e-07
Identities = 32/88 (36%), Positives = 52/88 (59%), Gaps = 1/88 (1%)
Query: 20 GFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVL 78
GF +E I G +TNS A++A++ H D A+ A+ K+S + K ++G+ R +
Sbjct: 34 GFTILEAIGGVMTNSTAILANAVHDFGDSIAVGQAWYFEKLSGRTGDKRYSYGYQRFSIF 93
Query: 79 GALVNAVFLVALCFSITVEAVKRFIEFE 106
GALV+A+ ++A F + VEAV R + E
Sbjct: 94 GALVSALMMLASSFLVLVEAVPRLLHPE 121
>UniRef50_Q5FM42 Cluster: Cation efflux protein; n=5;
Lactobacillus|Rep: Cation efflux protein - Lactobacillus
acidophilus
Length = 299
Score = 70.5 bits (165), Expect = 6e-11
Identities = 36/86 (41%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLGALVN 83
E + G + S+AL++D+ H LSDV A+I++F++ +S + + N TFG+ RAE L A N
Sbjct: 24 EFLGGIFSGSLALLSDAVHNLSDVGAIILSFIAHLISRRSRNNNKTFGYERAETLAAFTN 83
Query: 84 AVFLVALCFSITVEAVKRFIEFEVIH 109
V L+ + + VEA++RF E E IH
Sbjct: 84 GVVLIVISVVLFVEAIQRFWEPEHIH 109
Score = 64.9 bits (151), Expect = 3e-09
Identities = 43/159 (27%), Positives = 80/159 (50%), Gaps = 14/159 (8%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
G++N++ F+H+LSDAL S+ VV A+ ++ W ++DP + +
Sbjct: 137 GNLNVRSTFIHMLSDALSSVAVVIGAVFIYF--WNVT-WLDPVLTILVSLFVLHEAYEIT 193
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIR-----CR 301
+++ +L+++ P I +D + + + V +H HVW+ + D I+ AHI C
Sbjct: 194 MKAANVLMESNP-DIDLDKVNEIVLSFPKVTNIHHVHVWRYSDDFIMMDAHINVAPDMCA 252
Query: 302 NLSE--YMKIAEKVKEFFHNEGIHSTTIQPEFVEGPQDE 338
+ E Y +I +K+K+ GI+ T+Q E G D+
Sbjct: 253 DELEQLYQEIGKKLKK---ELGINHITLQAECKRGQNDD 288
>UniRef50_A0BG38 Cluster: Chromosome undetermined scaffold_105,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_105,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 603
Score = 70.5 bits (165), Expect = 6e-11
Identities = 50/206 (24%), Positives = 85/206 (41%), Gaps = 6/206 (2%)
Query: 9 CRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-K 67
CRL+ + + F E+I G S+A+++D+ HM SD++ I+ S+ + K S K
Sbjct: 62 CRLIAVSVVCIIFLVAEVIGGLWAQSLAILSDAAHMFSDMSGFFISIFSIWLGQKPASQK 121
Query: 68 NTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXX 127
+FG+ RAEV+GAL + + + L + EA R +E ++ +P
Sbjct: 122 MSFGYHRAEVIGALGSIILIWGLTILLFYEATIRVLEEAIVTDPLIMLITAGFGLFCNLV 181
Query: 128 XXXXXHVPPP-----SNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKS 182
H P N+ H N D HN N D ++ +H K
Sbjct: 182 MAKVLHSSPTGGHDHGNIMHQCSGHNHGHDHGHEHNHDHNHNHDHSHSHEESHSHSKQKQ 241
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIV 208
+++K V + + L+V
Sbjct: 242 QKKKKKISIKQKRQQVSENGISMLVV 267
Score = 68.9 bits (161), Expect = 2e-10
Identities = 45/190 (23%), Positives = 85/190 (44%), Gaps = 15/190 (7%)
Query: 157 HNSTDNEETDEM---VKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSAL 213
H+ +D+ D KK+ K+ ++ + N+K +HV+ D L S+ V+ +A+
Sbjct: 400 HDHSDDHSHDHSHNHKKKSNKLKSKNLTEINEHDNHNLKAAMIHVIGDILQSIGVLIAAI 459
Query: 214 VVWLTEWK----------YKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQV 263
++++ K Y Y DP + + +E +L++ P ++ +
Sbjct: 460 LIYIFGQKKDENNQIVFTYWQYADPFCTYLFSILVLFTTFGVAKECLRVLMEGTPQNLII 519
Query: 264 DAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGIH 323
+ +LK + V VH+ H+W L+ + SAHI C EY + K + GI+
Sbjct: 520 EEFNEKLKAIHRVKEVHDLHIWSLSVGKPAMSAHIVCIENPEY--VLRKATKLCRQFGIY 577
Query: 324 STTIQPEFVE 333
+TIQ E +
Sbjct: 578 HSTIQIELYD 587
>UniRef50_Q5HTV1 Cluster: Cation efflux family protein; n=11;
Campylobacter|Rep: Cation efflux family protein -
Campylobacter jejuni (strain RM1221)
Length = 316
Score = 70.1 bits (164), Expect = 8e-11
Identities = 35/91 (38%), Positives = 59/91 (64%), Gaps = 3/91 (3%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS--KNTFGW 72
L +T V+ I ++NS+AL++D+ HM SDV AL ++FL++ ++ +KW + TFG+
Sbjct: 45 LLMTFSMMLVQFIYSILSNSLALLSDTLHMFSDVFALALSFLAI-IAVEKWQDHQKTFGY 103
Query: 73 ARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
R EVL A +NA+ ++ I EA+++FI
Sbjct: 104 FRLEVLVAFINALTIILSALFIIYEAIEKFI 134
Score = 65.7 bits (153), Expect = 2e-09
Identities = 43/145 (29%), Positives = 76/145 (52%), Gaps = 8/145 (5%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++NMK FLH++SD LGSL V+ +VV+ + YID LL+
Sbjct: 170 NVNMKSAFLHMMSDLLGSLAVIIGGIVVYFSGIV---YIDTILAIVLSILLLRWAIILLK 226
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR--NLSE 305
+S+ +LL++ P + ++ +++ L V V + H+ Q+ ++AS H++ R NL E
Sbjct: 227 QSANVLLESSP--VDIEKVRQVLLLNPSVDEVVDLHITQITNKMLVASMHLKVRVCNLKE 284
Query: 306 YMKIAEKVK-EFFHNEGIHSTTIQP 329
+ K+++ + + H I TIQP
Sbjct: 285 FEKLSQDLSHKLLHEFEIGHITIQP 309
>UniRef50_Q4ECE6 Cluster: Cation efflux family protein; n=12;
Rickettsiales|Rep: Cation efflux family protein -
Wolbachia endosymbiont of Drosophila ananassae
Length = 322
Score = 70.1 bits (164), Expect = 8e-11
Identities = 34/104 (32%), Positives = 69/104 (66%), Gaps = 2/104 (1%)
Query: 2 GRYSGKKC-RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM 60
G++S + RL+ + + F+E++ G I++S+AL++D+ HML+D+ AL++++L+ +
Sbjct: 31 GKHSAAQSKRLIYSIIIVAITMFMEIVGGIISHSLALLSDAGHMLTDLFALVLSWLAHRF 90
Query: 61 SPKKWS-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
S KK + ++G+ R +++ A VN + L + I +E++KRFI
Sbjct: 91 SAKKSDLQRSYGYHRLQIIAAFVNGLTLFLIAVIIIIESIKRFI 134
Score = 67.3 bits (157), Expect = 6e-10
Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 10/159 (6%)
Query: 177 HKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXX 236
H C+S+ +N+K LHV+ D LGS+ + +++++ LT W+ +DP
Sbjct: 163 HSKCESN-----INIKSAVLHVIGDILGSVAAILASIIIMLTGWQ---IVDPILSVFVSV 214
Query: 237 XXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRL-KNVEGVMAVHEFHVWQLAGDRIIAS 295
+ +L+ S ILL+ P I + I+ ++ + V+ VH H W L+ + I +
Sbjct: 215 IILNSGYKILKNSCHILLEGTPEGISAEEIKSKITSELPEVIDVHHIHTWSLSDNYFIIT 274
Query: 296 AHIRCRNLSEYMKIAEKVKEFFHNE-GIHSTTIQPEFVE 333
H + + ++ + ++K+ ++ I +T++ E+ E
Sbjct: 275 MHAKIKQNVQHTNVLYEIKKILLDKFEIAHSTVEIEYDE 313
>UniRef50_P72068 Cluster: Putative uncharacterized protein; n=1;
Nannocystis exedens|Rep: Putative uncharacterized
protein - Nannocystis exedens
Length = 290
Score = 70.1 bits (164), Expect = 8e-11
Identities = 36/142 (25%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++N++G +H+L+DALGSL + +A++ + W H D W +LR
Sbjct: 151 NINIRGALIHMLADALGSLGAIVAAVLASM--WAI-HAADSILSLGIAVLVLFSAWGVLR 207
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYM 307
+++ LL PTH+ + ++ L+ + GV +HE H+W + G ++ + + ++
Sbjct: 208 DATRALLDFAPTHLPQERVETELRGLAGVSEIHELHLWSVGGAPVLTAHLVPEPGVAPGD 267
Query: 308 KIAEKVKEFFHNEGIHSTTIQP 329
+A + G+ TT+QP
Sbjct: 268 XLARAEHLLREHLGVVHTTLQP 289
>UniRef50_A6LME7 Cluster: Cation diffusion facilitator family
transporter; n=1; Thermosipho melanesiensis BI429|Rep:
Cation diffusion facilitator family transporter -
Thermosipho melanesiensis BI429
Length = 294
Score = 70.1 bits (164), Expect = 8e-11
Identities = 39/150 (26%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXX 240
SS ++N+K FLH+LSD S+ I++ ++ + W +DP
Sbjct: 137 SSHSKENLNLKSAFLHILSDMFSSVGIIITGHVMSYYNIW----ILDPIITFVISGYIII 192
Query: 241 XXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC 300
+L+ES +++Q +P + +D +++ ++N V VH HVW L G + H+
Sbjct: 193 ESIKILKESIRVVMQGIPKGVDLDKVKKIIQNFSFVKDVHHIHVWSLDGIELYLEMHVTV 252
Query: 301 RNLSEYMKIAEKVKEFFHNEGIHSTTIQPE 330
+Y ++KE G +TIQ E
Sbjct: 253 DG-KDYDDYLRRIKETLKEHGFRHSTIQLE 281
Score = 67.3 bits (157), Expect = 6e-10
Identities = 29/80 (36%), Positives = 57/80 (71%), Gaps = 1/80 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKNTFGWARAEVLGALVN 83
E+I G ++ S+AL++D+ H LSD AL+I++ + K+S K +K T+G+ RAE++ +++N
Sbjct: 29 EIIGGIVSGSLALISDALHNLSDTGALLISYFARKISKKPVDNKYTYGYKRAELVASVIN 88
Query: 84 AVFLVALCFSITVEAVKRFI 103
L+++ FS+ +E +K+ +
Sbjct: 89 ITVLLSISFSLILEGIKKIL 108
>UniRef50_Q22541 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 360
Score = 70.1 bits (164), Expect = 8e-11
Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 176 NHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLT-EWKYKHYIDPXXXXXX 234
+H + ++N++ F+HVL D L SL V+ +AL ++ W IDP
Sbjct: 190 SHGHSHGGGNGDNINVRAAFIHVLGDLLQSLGVLVAALFIYFQPSWVI---IDPICTLVF 246
Query: 235 XXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIA 294
+LR++ ++LL+ P++I + L+++EGV VH+ +W L D+I
Sbjct: 247 SVIVLCTTIYILRDAMIVLLEGRPSNIDFAKVFSSLEDIEGVKKVHDLRIWSLTMDKIAL 306
Query: 295 SAHIRCRNLSEYMKIAEKVKEFF-HNEGIHSTTIQPE 330
S H+ S+ I + ++ +H TIQ E
Sbjct: 307 SVHLEIDANSQSQSILRETRKMLKQTYNVHEITIQIE 343
Score = 55.6 bits (128), Expect = 2e-06
Identities = 36/101 (35%), Positives = 62/101 (61%), Gaps = 7/101 (6%)
Query: 11 LLCMLCLTGGFFFV-ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KN 68
L +LCL FF V E+I G + S+A+V D+ H+L+D A+++I+ S+ ++ + S K
Sbjct: 56 LTVVLCL---FFMVCEVIGGVLAGSLAIVTDAAHLLTDFASVLISLFSLYIARRPPSQKM 112
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI--EFEV 107
+FG+ RAEVLGA + + + + V A+ R + ++EV
Sbjct: 113 SFGFHRAEVLGAFFSVFLIWIVTGVLVVLAIMRIVSGDYEV 153
>UniRef50_P13512 Cluster: Cobalt-zinc-cadmium resistance protein
czcD; n=5; Bacteria|Rep: Cobalt-zinc-cadmium resistance
protein czcD - Ralstonia metallidurans (strain CH34 /
ATCC 43123 / DSM 2839)
Length = 316
Score = 70.1 bits (164), Expect = 8e-11
Identities = 39/151 (25%), Positives = 74/151 (49%), Gaps = 5/151 (3%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
SS +N+KG +L V SD LGS+ V+ A+++ T W + +D
Sbjct: 139 SSGQSSSLNVKGAYLEVWSDLLGSVGVIAGAIIIRFTGWAW---VDSAIAVLIGLWVLPR 195
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAH-IRC 300
W LL+ S +LL+ VP + + +++++ GV + H+ H+W L + + H +
Sbjct: 196 TWILLKSSLNVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHIWALTSGKASLTVHVVND 255
Query: 301 RNLSEYMKIAEKVKEFFHNE-GIHSTTIQPE 330
++ M++ ++K+ ++ I TIQ E
Sbjct: 256 TAVNPEMEVLPELKQMLADKFDITHVTIQFE 286
Score = 68.5 bits (160), Expect = 2e-10
Identities = 37/97 (38%), Positives = 55/97 (56%), Gaps = 1/97 (1%)
Query: 6 GKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW 65
G + L L LTG F E++ G +T S+AL++D+ HML+D AL IA ++ ++ +
Sbjct: 12 GNERSLKIALALTGTFLIAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPA 71
Query: 66 -SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
K TFG+ R E+L A NA+ L + I EA R
Sbjct: 72 DKKRTFGYYRFEILAAAFNALLLFGVAIYILYEAYLR 108
>UniRef50_Q03ZB0 Cluster: Co/Zn/Cd efflux system component; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Co/Zn/Cd efflux system component - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 305
Score = 69.7 bits (163), Expect = 1e-10
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N K ++H+L+DA S+ V+ + L++ +T W H IDP WP+++
Sbjct: 155 LNAKTAYIHLLADAGVSVGVIIAGLLIQVTGW---HVIDPIVSMIIGVIIAVTSWPVMKS 211
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC-RNLSEYM 307
+ + L VP ++ + R L EGV +H+ H+W L+ + H+ +N+ E
Sbjct: 212 TFNLALNGVPDNVNESDVLRYLSTHEGVEQLHDLHIWPLSTTEAAMTVHLSVKKNVDEQE 271
Query: 308 KIAEKVKEFFHNEGIHSTTIQPEFVEGPQDENEV 341
+A + I TIQ E E Q N +
Sbjct: 272 LLANISSDLREKYDISHVTIQIETNEFDQSCNVI 305
Score = 59.7 bits (138), Expect = 1e-07
Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 1/84 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-NTFGWARAEVLG 79
F EL+ + +S AL AD+FH LSDV AL+IA+L+V + + +K +T+GW +L
Sbjct: 25 FVLSELVFAKLAHSTALFADAFHNLSDVLALMIAWLAVVVFGLQATKRHTYGWHNMSILA 84
Query: 80 ALVNAVFLVALCFSITVEAVKRFI 103
++ N + L+ +I E+++ I
Sbjct: 85 SVFNTILLIFAVITIFYESIRNLI 108
>UniRef50_A6Q136 Cluster: Cation efflux system protein, CDF family;
n=2; unclassified Epsilonproteobacteria|Rep: Cation
efflux system protein, CDF family - Nitratiruptor sp.
(strain SB155-2)
Length = 301
Score = 69.7 bits (163), Expect = 1e-10
Identities = 40/148 (27%), Positives = 72/148 (48%), Gaps = 7/148 (4%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++N+K +LH+L+D S+ VV L L ++ + +++DP +++
Sbjct: 141 NINIKAAYLHLLTDVFTSIAVVVGGL---LMQFYHIYWVDPAVSLLIAFYLIYASIDIVK 197
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN---LS 304
ES IL++ P I ++ I +K +E V +H H+W+L I AHI + L
Sbjct: 198 ESIAILMEFAPKSIDIEKIADEVKKIEKVENIHHIHIWRLGEHDIFLEAHIDFKENLPLQ 257
Query: 305 EYMKIAEKVKEFFHNE-GIHSTTIQPEF 331
E +I +++ + I T+QPEF
Sbjct: 258 EVTQIIADIEKLLREKFYISHVTLQPEF 285
Score = 60.9 bits (141), Expect = 5e-08
Identities = 29/79 (36%), Positives = 52/79 (65%), Gaps = 1/79 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLGALVN 83
+++ G NS++L++D+ H LSDV +L+IA+ + ++ K +K+ TFG RAE++ AL N
Sbjct: 27 QIVGGIYANSLSLLSDAMHNLSDVLSLVIAWAANTIAAKPSTKSYTFGLKRAEIIAALFN 86
Query: 84 AVFLVALCFSITVEAVKRF 102
A L+ + + +EA +F
Sbjct: 87 ASLLLGIAIFLVIEAFHKF 105
>UniRef50_Q07XG6 Cluster: Cation diffusion facilitator family
transporter; n=4; Gammaproteobacteria|Rep: Cation
diffusion facilitator family transporter - Shewanella
frigidimarina (strain NCIMB 400)
Length = 300
Score = 69.3 bits (162), Expect = 1e-10
Identities = 36/142 (25%), Positives = 72/142 (50%), Gaps = 5/142 (3%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++N++ F+H LSDA S++V+ + ++ L +W + +D L +
Sbjct: 147 NLNLRAAFIHNLSDAFASVVVIVAGSLIILYQW---YVVDLLATILISVYVVYHGIILAK 203
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYM 307
+S IL+Q VP I +D I + ++++E V V HVWQL + + + + ++
Sbjct: 204 QSIRILMQAVPVDIDIDKICKDIESMENVEKVRHIHVWQLDDSEVYLETSVNLKTMEQFQ 263
Query: 308 KIAEKVKEFFHNE-GIHSTTIQ 328
+ + +K+ + GIH +TI+
Sbjct: 264 DL-KPIKDLLAAQYGIHHSTIE 284
Score = 63.3 bits (147), Expect = 9e-09
Identities = 30/79 (37%), Positives = 55/79 (69%), Gaps = 1/79 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKNTFGWARAEVLGALVN 83
++I G ++ S++L+AD+ H LSD A++IA ++ K++ K S+ TFG+ RAE++GAL+N
Sbjct: 32 QVIGGVLSGSLSLIADALHNLSDAGAIVIAIVARKIARKPANSQMTFGFKRAEIIGALIN 91
Query: 84 AVFLVALCFSITVEAVKRF 102
+ L+ L + AV+++
Sbjct: 92 STTLIILGIYLIYAAVEKY 110
>UniRef50_O45923 Cluster: Putative uncharacterized protein ttm-1;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein ttm-1 - Caenorhabditis elegans
Length = 410
Score = 69.3 bits (162), Expect = 1e-10
Identities = 37/155 (23%), Positives = 73/155 (47%), Gaps = 4/155 (2%)
Query: 177 HKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXX 236
H S + D ++N++ +HV+ D + S+ V+ +AL++ T W DP
Sbjct: 241 HSSHGHAHDGKNVNVRAALIHVIGDLVQSIGVLIAALIIRFTGWTLA---DPICTFLFSI 297
Query: 237 XXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASA 296
++R+ +L++ P+H + +++ L +EGV VH+ H+W + D+ S
Sbjct: 298 IVLFTTVTVMRDIFFVLMEATPSHYDLSDVKKALSALEGVKGVHDLHLWSIGMDKTAFSV 357
Query: 297 HIRCRNLSEYMK-IAEKVKEFFHNEGIHSTTIQPE 330
H+ + + M+ +AE G+ T+Q E
Sbjct: 358 HLALESPNRAMENVAEARSLIRRRFGVAVATVQVE 392
Score = 62.5 bits (145), Expect = 2e-08
Identities = 33/97 (34%), Positives = 56/97 (57%), Gaps = 1/97 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-T 69
L + L+ F E + G+ S+A++ D+ HMLSD+ + II+ +++ + SK +
Sbjct: 105 LWAVAALSAVFIAAEFVGGFWAQSLAIMTDAGHMLSDLLSFIISIFAIRCARLPASKRLS 164
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFE 106
FG+ RAEVLGAL + + L L + V A++R + E
Sbjct: 165 FGYERAEVLGALTSVIILWVLTTVLVVVAIQRIVNNE 201
>UniRef50_O14863 Cluster: Zinc transporter 4; n=33;
Euteleostomi|Rep: Zinc transporter 4 - Homo sapiens
(Human)
Length = 429
Score = 69.3 bits (162), Expect = 1e-10
Identities = 38/97 (39%), Positives = 60/97 (61%), Gaps = 1/97 (1%)
Query: 8 KCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK 67
K RL L F EL+ GYI NS+A++ D+ HML+D++A+I+ L++ +S K +K
Sbjct: 111 KARLTIAAVLYLLFMIGELVGGYIANSLAIMTDALHMLTDLSAIILTLLALWLSSKSPTK 170
Query: 68 N-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
TFG+ R EVL A+++ + + L + EAV+R I
Sbjct: 171 RFTFGFHRLEVLSAMISVLLVYILMGFLLYEAVQRTI 207
Score = 59.7 bits (138), Expect = 1e-07
Identities = 36/153 (23%), Positives = 74/153 (48%), Gaps = 7/153 (4%)
Query: 180 CKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYI-DPXXXXXXXXXX 238
C+ + + ++ F+H L D + S VG + ++ +K ++ I DP
Sbjct: 260 CERNHGQDSLAVRAAFVHALGDLVQS---VGVLIAAYIIRFKPEYKIADPICTYVFSLLV 316
Query: 239 XXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ ++ ++ +I+L+ VP+H+ VD I+ L +E V +V + ++W L + A HI
Sbjct: 317 AFTTFRIIWDTVVIILEGVPSHLNVDYIKEALMKIEDVYSVEDLNIWSLTSGKSTAIVHI 376
Query: 299 RC--RNLSEYMKIAEKVKEFFHNE-GIHSTTIQ 328
+ + S++ ++ K N G++ TIQ
Sbjct: 377 QLIPGSSSKWEEVQSKANHLLLNTFGMYRCTIQ 409
>UniRef50_Q8F433 Cluster: Cobalt-zinc-cadmium resistance protein
czcD; n=4; Leptospira|Rep: Cobalt-zinc-cadmium
resistance protein czcD - Leptospira interrogans
Length = 317
Score = 68.9 bits (161), Expect = 2e-10
Identities = 34/98 (34%), Positives = 65/98 (66%), Gaps = 1/98 (1%)
Query: 6 GKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW 65
G K +L + ++ FFVEL G+ + S+AL+AD+ H+++D AL ++ ++V +S KK
Sbjct: 18 GLKRSILLAILVSISIFFVELFGGFQSGSIALLADAGHIITDTIALSLSLIAVLLSSKKP 77
Query: 66 S-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
+ + +FG+ R E+L +L+N++ + + F I E+++RF
Sbjct: 78 NYRFSFGYYRIEILTSLLNSILIFGISFYIFYESIERF 115
Score = 66.5 bits (155), Expect = 1e-09
Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 4/144 (2%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++N+K ++HVLSD L ++ V+ ++++++T W ++IDP W + R
Sbjct: 151 NINIKSAYVHVLSDLLSTVGVLVGSILIYITNW---NWIDPLISVLISILILRSAWGIFR 207
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYM 307
E+ +LL++ P ++ I ++ VEGV + ++H W + + + +L
Sbjct: 208 ETIFVLLESSPNTFEITHILEYVRKVEGVSQILDYHFWAITRGIYACTLRVSIVDLKFAE 267
Query: 308 KIAEKVKEFFHNE-GIHSTTIQPE 330
++ K + + G TIQ E
Sbjct: 268 EVVFKFNQILKSSFGFDFVTIQCE 291
>UniRef50_Q606W3 Cluster: Cation efflux family protein; n=2;
Bacteria|Rep: Cation efflux family protein -
Methylococcus capsulatus
Length = 314
Score = 68.9 bits (161), Expect = 2e-10
Identities = 37/100 (37%), Positives = 61/100 (61%), Gaps = 1/100 (1%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK- 63
+G + RL+ L LTGGF E + G+ NS+AL+ D+ H LSDV AL +++ +++++ +
Sbjct: 15 AGAQGRLVWALILTGGFVVFEALAGWKANSLALLTDAVHNLSDVLALGLSWYAMRLTAQP 74
Query: 64 KWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
+ TFG+ RA +L AL N+ LV + I +A R +
Sbjct: 75 AHAAKTFGYHRAGILAALANSAGLVGVALYILYDAYVRLL 114
Score = 62.5 bits (145), Expect = 2e-08
Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 6/145 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+NM+ FLH+L D + +L + + + + T +++DP L+ E
Sbjct: 150 LNMRSAFLHLLGDVVSTLGAIAAGVAIRYTGL---YWLDPAVSVLIALLILWNAKGLMAE 206
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN--LSEY 306
ILL++ P + + ++ R + VEGV VH HVW ++ + SAHI + LSE
Sbjct: 207 VMDILLESTPRDVDMGSMVRDMMQVEGVHGVHHLHVWSISRQLRMLSAHIVTDDIRLSEG 266
Query: 307 MKIAEKVKEFF-HNEGIHSTTIQPE 330
+ ++V GI TT+Q E
Sbjct: 267 EGLQKRVTRLLAQRYGIAHTTLQLE 291
>UniRef50_Q5FQH8 Cluster: Cation efflux system protein; n=1;
Gluconobacter oxydans|Rep: Cation efflux system protein
- Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 351
Score = 68.9 bits (161), Expect = 2e-10
Identities = 34/112 (30%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++G FLH+ +DA+ + VV + L++ T + IDP W LLR
Sbjct: 197 LNVRGAFLHMAADAVMAFSVVIAGLLIAFTGYTI---IDPIMSLIVSVSIVIGTWSLLRS 253
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC 300
S + L VP I DA+Q L +++GV +H H+W ++ + H+ C
Sbjct: 254 SLNLALDAVPAGIDPDAVQAALLSLDGVSGLHHLHIWAMSTTETALTVHLVC 305
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/83 (33%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNTFGWARAEVLGALVN 83
E++ G +S++L+AD+ H LSDV L A+L+ ++ + S + T+G R+ +L AL N
Sbjct: 82 EVLWGVWAHSLSLLADAGHNLSDVLGLAGAWLAQVLATRPSSARFTYGLRRSTILSALAN 141
Query: 84 AVFLVALCFSITVEAVKRFIEFE 106
A L+ + I E+V R +
Sbjct: 142 ATILLLVTGGIVWESVLRLFSHQ 164
>UniRef50_A0VV15 Cluster: Cation diffusion facilitator family
transporter; n=6; Alphaproteobacteria|Rep: Cation
diffusion facilitator family transporter -
Dinoroseobacter shibae DFL 12
Length = 328
Score = 68.9 bits (161), Expect = 2e-10
Identities = 36/91 (39%), Positives = 58/91 (63%), Gaps = 3/91 (3%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
SGK L+ LTG +F +EL VG T S+A+++D+FH LS V +++A + +++ +
Sbjct: 13 SGKA--LVISAWLTGVYFVIELAVGLWTGSIAVLSDAFHTLSAVGGVLVAITAQRIARRP 70
Query: 65 W-SKNTFGWARAEVLGALVNAVFLVALCFSI 94
S +FGW RAE++GALVN FL+ + +
Sbjct: 71 ADSTRSFGWYRAEIIGALVNGGFLLGMALLV 101
Score = 66.5 bits (155), Expect = 1e-09
Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 4/148 (2%)
Query: 184 SDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXW 243
S +N +G H++ +GSL+++ +ALV+ T + IDP
Sbjct: 141 SSKDDLNARGALWHIIQTFVGSLLIIVTALVIEFTGFLA---IDPILGMAFGVVLLWASV 197
Query: 244 PLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNL 303
+++E+ IL++ P +DA+ L +GV+ VH H W L + SAHIR ++
Sbjct: 198 GVIKEAVHILMEGTPEGTDLDAVTADLNGQDGVLDVHHVHAWTLTSGKHAFSAHIRHQSP 257
Query: 304 SEYMKIAEKV-KEFFHNEGIHSTTIQPE 330
+E + + + G H T+Q E
Sbjct: 258 AEAADLLNRAYRRLTEQHGFHMVTLQLE 285
>UniRef50_A7I6Y5 Cluster: Cation diffusion facilitator family
transporter; n=1; Candidatus Methanoregula boonei
6A8|Rep: Cation diffusion facilitator family transporter
- Methanoregula boonei (strain 6A8)
Length = 317
Score = 68.9 bits (161), Expect = 2e-10
Identities = 43/144 (29%), Positives = 71/144 (49%), Gaps = 5/144 (3%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N + FLHV+ D L SL V+ +AL + LT + +DP + +L E
Sbjct: 152 LNTRSAFLHVIGDLLSSLAVIVAALWIALTG---QTVVDPLLGLAISVLILFSSFSILAE 208
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIR-CRNLSEYM 307
S ILLQ P + ++ + +++V GV VH H+W L + + AH+ C N E
Sbjct: 209 SFRILLQFAPRDVPIEDVIAAMESVPGVSGVHNVHLWTLCSNINVLDAHVYCCENDPETR 268
Query: 308 -KIAEKVKEFFHNEGIHSTTIQPE 330
+I E++K + I +T++ E
Sbjct: 269 EQIKEEIKHRLEHFRIGHSTLEFE 292
Score = 64.1 bits (149), Expect = 5e-09
Identities = 33/100 (33%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 4 YSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK 63
++ +K L + LT F E+I GY++ S++L+ D HML DV AL ++ ++ M+ +
Sbjct: 18 HNSRKKPLKLAIALTALIFVAEIIGGYLSGSLSLLGDGAHMLQDVVALGLSLGAMTMAER 77
Query: 64 -KWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
TFG+ R E+ A++N + L+ + I +EA+ RF
Sbjct: 78 LPTPTRTFGYHRLEIAAAVINGLLLIGVSALIILEALARF 117
>UniRef50_Q5ZRY2 Cluster: Cation efflux system protein; n=4;
Legionella pneumophila|Rep: Cation efflux system protein
- Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 307
Score = 68.5 bits (160), Expect = 2e-10
Identities = 44/147 (29%), Positives = 73/147 (49%), Gaps = 6/147 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++G +LH+ DAL S+ VV SA V++LT W + IDP W L +
Sbjct: 151 LNIRGAYLHLFYDALISVGVVLSAGVLYLTGWLW---IDPVVGLLIALVILKGTWSLFAD 207
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC--RNLSEY 306
S +++ VP I + L + GV ++H+ H+W ++ S H+ +LS+
Sbjct: 208 SFRLIIDGVPRDISWIKVSDFLLAIPGVKSIHDLHIWAISTKENALSVHLFMPEESLSDD 267
Query: 307 MKIAEKVKEFFHNEGIHSTTIQPEFVE 333
++ E V++ H+ I TIQ E E
Sbjct: 268 LR-RELVEKLKHDFSIQHVTIQVEKTE 293
Score = 61.7 bits (143), Expect = 3e-08
Identities = 34/91 (37%), Positives = 52/91 (57%), Gaps = 2/91 (2%)
Query: 19 GGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSV-KMSPKKWSKNTFGWARAEV 77
G F +++I Y+ NS +L+AD+FH L DV LI+A+++ M K K T+G+ + +
Sbjct: 31 GLFVVMQIIFAYLANSTSLLADAFHNLGDVLGLILAWVATGLMKRKPTHKATYGFKKTSI 90
Query: 78 LGALVNAVFLVALCFSITVEAV-KRFIEFEV 107
L AL N LV C I +A+ K F E+
Sbjct: 91 LAALANGALLVFTCGIIATDAMYKLFSPTEI 121
>UniRef50_Q5CSE6 Cluster: Cation diffusion facilitator like membrane
protein transporter, 6x transmembrane domains; n=2;
Cryptosporidium|Rep: Cation diffusion facilitator like
membrane protein transporter, 6x transmembrane domains -
Cryptosporidium parvum Iowa II
Length = 459
Score = 68.5 bits (160), Expect = 2e-10
Identities = 28/84 (33%), Positives = 58/84 (69%), Gaps = 1/84 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLG 79
F +E++VG ++NS+AL++D+ H++SD+ + I+ L + +S +K + +FG+ RAE+LG
Sbjct: 40 FTLIEVVVGILSNSLALISDASHLISDICSYFISLLGIHLSKRKATNTMSFGYNRAEILG 99
Query: 80 ALVNAVFLVALCFSITVEAVKRFI 103
AL++ + + + + EA++R +
Sbjct: 100 ALLSILLIWFMTIMLVYEAIQRML 123
Score = 61.7 bits (143), Expect = 3e-08
Identities = 41/194 (21%), Positives = 81/194 (41%), Gaps = 5/194 (2%)
Query: 140 VRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVL 199
+ + T ++NS R + + + NH + K SS+ + +K ++HVL
Sbjct: 231 LNNYTNLMNSPVIRRVNSGLKECSGRQNDYSHLHSSNHYTSKHSSEQESLALKSAYIHVL 290
Query: 200 SDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVP 258
D L ++ +++ L+++ W DP +L++S+ +L++ P
Sbjct: 291 GDILQNIGVMIAGLLILYNPAWTIA---DPLCTILFSFFVLATTIKILKDSANVLMEGTP 347
Query: 259 THIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFH 318
I ++IQ + V+ VH+ HVW ++ S HI + +
Sbjct: 348 IGIDCESIQNDFLKLSSVLEVHDLHVWSVSVGVPALSCHIVVASEDNARFTLRYATDLCQ 407
Query: 319 NE-GIHSTTIQPEF 331
+ GI TTIQ ++
Sbjct: 408 KKYGIFHTTIQIDY 421
>UniRef50_A1B355 Cluster: Cation diffusion facilitator family
transporter; n=3; Rhodobacteraceae|Rep: Cation diffusion
facilitator family transporter - Paracoccus
denitrificans (strain Pd 1222)
Length = 311
Score = 68.1 bits (159), Expect = 3e-10
Identities = 35/91 (38%), Positives = 58/91 (63%), Gaps = 5/91 (5%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWA 73
L LTG +++ GY+ +S AL+AD H LSD AL++AF + +++ + S ++GW
Sbjct: 33 LALTGA----QILGGYVADSTALIADGVHNLSDALALVLAFGARRLARRPASPGMSYGWG 88
Query: 74 RAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
RAEV+ A VN + L+A+ + +EA+ R +E
Sbjct: 89 RAEVVAAFVNYIALIAISVWLGIEALGRMVE 119
Score = 56.8 bits (131), Expect = 8e-07
Identities = 35/143 (24%), Positives = 59/143 (41%), Gaps = 4/143 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++ FLH L+DA S+ V+ ++W W H DP +
Sbjct: 154 VNIRAAFLHNLADAAVSVAVILGGALIWAFGW---HLADPVLTLLISGVILWHVGQEIGP 210
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
+L+ P + A+ + VEGV H H+WQ+ R S H+ R+ ++ +
Sbjct: 211 VMRMLMLAAPAGVDHAALIGAMAGVEGVAGAHHLHLWQIDERRTALSVHLVMRDGADAVM 270
Query: 309 IAEKVKEFFHNE-GIHSTTIQPE 330
+ K + GI TI+ E
Sbjct: 271 AVRQAKAMLRRDFGIDHATIEAE 293
>UniRef50_A0ZGF9 Cluster: Cation efflux system protein; n=1;
Nodularia spumigena CCY 9414|Rep: Cation efflux system
protein - Nodularia spumigena CCY 9414
Length = 326
Score = 68.1 bits (159), Expect = 3e-10
Identities = 43/101 (42%), Positives = 63/101 (62%), Gaps = 4/101 (3%)
Query: 5 SGKKCRLLCMLC-LTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMS-- 61
S +K ++L + L FF VE VG + S++L AD+ HM SD+AAL+I+ S ++
Sbjct: 21 SQQKTKILWLAAGLLTCFFVVEWTVGLWSQSLSLQADAGHMFSDIAALVISLFSTYLAQQ 80
Query: 62 PKKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRF 102
P K K TFG R EVL AL+N + L+A+ IT EA++R+
Sbjct: 81 PAK-GKATFGNQRVEVLAALLNGLSLLAIATFITWEAIQRW 120
Score = 62.9 bits (146), Expect = 1e-08
Identities = 34/143 (23%), Positives = 72/143 (50%), Gaps = 6/143 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++G LH+++D S+ V+ +A+++ L +W + D PL++E
Sbjct: 157 LNLQGALLHIIADTASSVGVIIAAVMIHLWDW---WWADVAISLVVATFTGVSALPLVQE 213
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAH--IRCRNLSEY 306
S I L+ P I +++ +K+ GV+ V + H+W ++ ++++ A+ + C E
Sbjct: 214 SIKIFLEYAPKSIDPVEVEKLIKSFAGVVQVEKLHIWTISSNKVMLCANVIVECATNQER 273
Query: 307 MKIAEKVK-EFFHNEGIHSTTIQ 328
++ K++ N I TT+Q
Sbjct: 274 DRLINKLQIHLQENFKIAETTLQ 296
>UniRef50_A6RG56 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 906
Score = 67.7 bits (158), Expect = 4e-10
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNT 69
++ +CL GF V+L G +T S+ L++DS HML D AL + + MS KW +
Sbjct: 540 KIFYFMCLNFGFMLVQLSYGILTGSLGLLSDSIHMLFDCFALAVGLCAAVMS--KWPPSV 597
Query: 70 ---FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
+G+ + + L N +FL+ + I EA++R + +H
Sbjct: 598 RFPYGYGKVDTLAGFANGIFLMIISIEIVYEAIERLVSGSEVH 640
Score = 45.6 bits (103), Expect = 0.002
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 4/108 (3%)
Query: 190 NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRES 249
NM G+FLH+L+D LGS+ VV S ++V +W DP PL+ +
Sbjct: 693 NMHGIFLHILADTLGSVAVVLSTVLVHFYKWS---GFDPIASCLIAILIFASAVPLVAST 749
Query: 250 SLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAH 297
S LL +P ++ ++ L V + V + V + D I+ H
Sbjct: 750 SKTLLLALPADVEY-RLRDALAGVSTLRGVAGYSVPKFWLDDIVDHDH 796
>UniRef50_A4M7M1 Cluster: Cation diffusion facilitator family
transporter; n=1; Petrotoga mobilis SJ95|Rep: Cation
diffusion facilitator family transporter - Petrotoga
mobilis SJ95
Length = 300
Score = 67.3 bits (157), Expect = 6e-10
Identities = 33/100 (33%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKN 68
RLL + L G E++ G +NS+AL++D+ H L+D A++I++++ +S KK SK
Sbjct: 15 RLLFSVILNFGITITEILGGIFSNSLALLSDAIHNLNDTTAILISYIARVLSKKKRDSKR 74
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
T+G+ R E L A VN L+ + + +E + + +I
Sbjct: 75 TYGYKRVETLAAFVNTEILMVIAVYLLIEGINKLSNPSII 114
Score = 64.1 bits (149), Expect = 5e-09
Identities = 33/118 (27%), Positives = 60/118 (50%), Gaps = 5/118 (4%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
S ++N++ F+H+LSD S+ +++G+ L+++ + + +D
Sbjct: 139 SGSKTNLNVRATFVHILSDTFSSIFVIIGAFLIIY----QKLYIVDAIFTLMISGYIFVE 194
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIR 299
PLL+ + ILLQ PT I+++ I+ +L+ + V VH H+W G AHIR
Sbjct: 195 SVPLLKNTVNILLQGTPTDIEIEKIKAKLEKFDFVKDVHHIHIWTTDGKDKYMEAHIR 252
>UniRef50_A0FTM8 Cluster: Cation diffusion facilitator family
transporter; n=5; Proteobacteria|Rep: Cation diffusion
facilitator family transporter - Burkholderia phymatum
STM815
Length = 373
Score = 66.9 bits (156), Expect = 7e-10
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++G FLH+L+DA S V S L + T W + +DP W LLR+
Sbjct: 217 LNIRGAFLHMLADAAVSAAVAVSGLAIVFTGWTW---LDPVMSLVVVAVIVYGTWGLLRD 273
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
S + L VP + + I+ L GV VH+ HVW L+ SAH+
Sbjct: 274 SLSLALNGVPRGVDMQKIRAYLAAQPGVTDVHDLHVWALSTTGNALSAHL 323
Score = 54.0 bits (124), Expect = 6e-06
Identities = 31/81 (38%), Positives = 50/81 (61%), Gaps = 1/81 (1%)
Query: 24 VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNTFGWARAEVLGALV 82
V+ + G + NS AL+AD+ H LSDV L++A+ + ++ ++ S + TFG + +L +L+
Sbjct: 101 VQGMYGVLANSTALLADAGHNLSDVLGLLLAWGATWLATRRPSARYTFGLGGSSILASLL 160
Query: 83 NAVFLVALCFSITVEAVKRFI 103
NA L+ C I EAV R I
Sbjct: 161 NAGLLLFACGVIVAEAVGRLI 181
>UniRef50_Q4D6N1 Cluster: Cation transporter protein, putative; n=3;
Trypanosoma|Rep: Cation transporter protein, putative -
Trypanosoma cruzi
Length = 608
Score = 66.9 bits (156), Expect = 7e-10
Identities = 36/96 (37%), Positives = 53/96 (55%), Gaps = 2/96 (2%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNT 69
RL LT +EL+ G NS+ LV+DSFHML D ++ + + +S K T
Sbjct: 315 RLFSFFLLTVAVMVLELLYGISANSLGLVSDSFHMLLDSVSIAVGLFAAFVSSLASDKMT 374
Query: 70 --FGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
FG+AR VLG +NAV L+ + + VE+V+R +
Sbjct: 375 HPFGYARYRVLGGFINAVLLLFIALFVVVESVERIM 410
Score = 52.4 bits (120), Expect = 2e-05
Identities = 38/149 (25%), Positives = 70/149 (46%), Gaps = 12/149 (8%)
Query: 177 HKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXX 236
H C S D H N++G++LH+L+D +GS+ V+ S++V+ LT K +DP
Sbjct: 448 HDGCSGSVD--H-NLRGIYLHILADLVGSINVMISSIVISLTGMK---IVDPICSLLSCV 501
Query: 237 XXXXXXWPLLRESSLILLQTVPTHIQVDAIQRR---LKNVEGVMAVHEFHVW---QLAGD 290
+PLL E+ +LL + + + +++ +K++E V +V W +
Sbjct: 502 FIALSAFPLLEETGKVLLLGGHPYDEENFLKKAIAGIKDIEDVNSVENICAWPHSTAPNE 561
Query: 291 RIIASAHIRCRNLSEYMKIAEKVKEFFHN 319
+ + R +++ KI V F N
Sbjct: 562 SAYCAIRVLARARADHGKIRFSVTHFMRN 590
>UniRef50_A4HFQ2 Cluster: Cation transporter, putative; n=3;
Leishmania|Rep: Cation transporter, putative -
Leishmania braziliensis
Length = 663
Score = 66.9 bits (156), Expect = 7e-10
Identities = 36/107 (33%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
++ +L L LT +E I G NS+ LV+DSFHM+ D +++I + +
Sbjct: 366 REYKLFVFLLLTVVIMLLEFIYGLAVNSLGLVSDSFHMMLDGTSIMIGLYAAHAASWLPD 425
Query: 67 KNT--FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
+ T FG+AR EV G VN + L+ + + VE+V+RF++ I P
Sbjct: 426 EKTHPFGYARYEVFGGFVNGILLLFIALYVMVESVQRFLDPPEIEGP 472
Score = 49.6 bits (113), Expect = 1e-04
Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 12/137 (8%)
Query: 187 GHM--NMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXW 243
GH+ NM+GV+LH+L+D LGS+ +++ S L+ W DP +
Sbjct: 509 GHVDHNMRGVYLHILADLLGSVSVIISSTLMYMFGLW----IADPICSAISAILVLLSAF 564
Query: 244 PLLRESSLILLQTVPTHIQ--VDAIQRRLKNVEGVMAVHEFHVWQ---LAGDRIIASAHI 298
PLL E+ +LL + P++ + D +++ L + V +W + I +
Sbjct: 565 PLLEETGRVLLLSAPSYERNYSDELRKVLLETALLQDVESPKLWMHSTAPRELTICTVAG 624
Query: 299 RCRNLSEYMKIAEKVKE 315
+ RN ++Y EK+ E
Sbjct: 625 KLRNNTDYTSAREKITE 641
>UniRef50_Q4P174 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 916
Score = 66.9 bits (156), Expect = 7e-10
Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIA-FLSVKMSPKKWSKN 68
++ L L F V+L+ G TNS+ L++D+ HM D AA+ + F SV + S
Sbjct: 494 KIFQFLLLNLAFMGVQLLWGVWTNSLGLISDAIHMFFDCAAIGMGLFASVMATWPTDSTF 553
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
T+G+AR E L N +FL+ + I EAV+R IE V++N
Sbjct: 554 TYGYARVETLSGFANGIFLILISIFIVFEAVQRIIEPPVMNN 595
Score = 50.8 bits (116), Expect = 5e-05
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 6/116 (5%)
Query: 187 GHM-NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPL 245
GH NM GV+LHV++D LGS+ V+ S L++ W DP PL
Sbjct: 650 GHSHNMMGVYLHVMADTLGSVGVIISTLLIGQFGWT---GFDPIASLFIAFMIVGSVIPL 706
Query: 246 LRESSLILLQTVPTHIQVDAIQR--RLKNVEGVMAVHEFHVWQLAGDRIIASAHIR 299
+ ES IL V H + + I+ L+ + GV++ H W + ++ ++
Sbjct: 707 VLESGRILCLEVGEHRETEMIEALDELRTLHGVVSYHSPRFWPKDAETLVGLIRVQ 762
>UniRef50_Q7UMH1 Cluster: Cation efflux system protein; n=1;
Pirellula sp.|Rep: Cation efflux system protein -
Rhodopirellula baltica
Length = 331
Score = 66.5 bits (155), Expect = 1e-09
Identities = 39/149 (26%), Positives = 73/149 (48%), Gaps = 8/149 (5%)
Query: 187 GHMNMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPL 245
G +N++ F+H L DA GS+ +++G+A V++L +W + +D W +
Sbjct: 168 GSLNVRAAFIHNLVDAAGSVAVLIGAAAVIYL-KWLW---VDSILTLLIATYILYQVWQM 223
Query: 246 LRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAH--IRCRNL 303
L E++ IL++ P + D + L ++GV +H H+W+L AH I
Sbjct: 224 LPEATRILMEGAPANFHFDEMMADLGGMDGVSGIHHVHLWELDESHRALEAHVVIEPTRF 283
Query: 304 SEYMKIAEKVKEFFHNE-GIHSTTIQPEF 331
+ I ++K + +E I +T++ EF
Sbjct: 284 EDLETIKREIKLYLTSEHNIRHSTLEFEF 312
Score = 63.7 bits (148), Expect = 7e-09
Identities = 32/96 (33%), Positives = 59/96 (61%), Gaps = 1/96 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
RLL + L ++I G ++ S+AL++D+ H SD +L+IA+++ +++ K+ ++
Sbjct: 40 RLLWSVLLNQALTVAQVIAGILSGSVALLSDAAHNFSDANSLLIAYIARRIARKEANQRY 99
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
TFG+ RAE++GA +N L + + EAV RF +
Sbjct: 100 TFGYRRAELIGATINLTLLAVVGCYLVYEAVHRFFD 135
>UniRef50_Q0BUV7 Cluster: Cation efflux system protein; n=1;
Granulibacter bethesdensis CGDNIH1|Rep: Cation efflux
system protein - Granulobacter bethesdensis (strain ATCC
BAA-1260 / CGDNIH1)
Length = 344
Score = 66.5 bits (155), Expect = 1e-09
Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+NM+GV+LHVLSD G + +AL++ +T W DP +++
Sbjct: 171 LNMRGVWLHVLSDLFGFAAAILAALIIMITGWVIA---DPLLSLIFAAMILRGAVSVVKG 227
Query: 249 SSLILLQTVPTHIQVDAIQRRLKN-VEGVMAVHEFHVWQLAG-DRII 293
S+ +LLQ P I +DAI L + + GV VH H W L G DR+I
Sbjct: 228 SAHVLLQGTPADIDLDAIASDLVHTIPGVQRVHHLHAWSLTGNDRLI 274
Score = 60.5 bits (140), Expect = 6e-08
Identities = 29/84 (34%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNTFGWARAEVLG 79
F E++ G ++ S+AL+AD+ HM+SDV +L++ + ++++ + S ++++G+ R EVL
Sbjct: 52 FLGAEIVGGLLSGSLALLADAGHMVSDVLSLLMGWAALRIGRRPSSTRHSYGFRRLEVLA 111
Query: 80 ALVNAVFLVALCFSITVEAVKRFI 103
A VN L+ + I +EAV+R +
Sbjct: 112 AFVNGSSLLIVSIWIVIEAVRRLL 135
>UniRef50_Q04D37 Cluster: Co/Zn/Cd efflux system component; n=2;
Oenococcus oeni|Rep: Co/Zn/Cd efflux system component -
Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 296
Score = 66.5 bits (155), Expect = 1e-09
Identities = 36/154 (23%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N K + H +DAL SL VV + ++ T W +DP W +L
Sbjct: 146 LNEKANYWHFFADALISLCVVFAGFIINFTNWVI---LDPLVSIFAAVFILFESWRVLCH 202
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
+ ++ VP +I + +++ L + + +++ H+W L+ + SAH++C ++YMK
Sbjct: 203 AFSLVTNGVPDNISENEVEKYLLSFPEIEKINDVHIWALSTTEVAISAHLQCNRPADYMK 262
Query: 309 IAEKVKEFFHNE-GIHSTTIQPEFVEGPQDENEV 341
I + + + I T+Q E + E+++
Sbjct: 263 ILDDATDGLRKKFDIDHVTLQLETSDKKHKESKI 296
Score = 57.2 bits (132), Expect = 6e-07
Identities = 32/87 (36%), Positives = 49/87 (56%), Gaps = 1/87 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-NTFGWARAEVLG 79
F E+I G S+ALV D+ H L DV L+IAF++V + +K +K +T+G+ +L
Sbjct: 26 FIVFEVICGVFAGSLALVTDAIHNLGDVLGLVIAFVAVILIKRKPTKHHTYGFYNTTILA 85
Query: 80 ALVNAVFLVALCFSITVEAVKRFIEFE 106
A N++ LVA + EA R + E
Sbjct: 86 AFTNSLILVASLAIVIWEAFLRLMNPE 112
>UniRef50_A1UA75 Cluster: Cation diffusion facilitator family
transporter; n=10; Corynebacterineae|Rep: Cation
diffusion facilitator family transporter - Mycobacterium
sp. (strain KMS)
Length = 298
Score = 66.5 bits (155), Expect = 1e-09
Identities = 35/94 (37%), Positives = 57/94 (60%), Gaps = 2/94 (2%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-- 67
R+L + FF +EL+ +S+AL+AD+ HML+D+ A+ + +V ++ + +
Sbjct: 17 RMLIAAAVLTAFFVLELVTALWIDSIALLADAGHMLTDLVAMFMGLTAVLLARRGSASPA 76
Query: 68 NTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
T+GW RAEV A+ NAV L+A+ I EAV+R
Sbjct: 77 RTYGWHRAEVFTAVANAVLLLAMAVFILYEAVER 110
Score = 65.3 bits (152), Expect = 2e-09
Identities = 38/140 (27%), Positives = 66/140 (47%), Gaps = 5/140 (3%)
Query: 191 MKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESS 250
+KG ++ V++D +GS+ V+ + +V T W Y D L R +
Sbjct: 150 VKGAYMEVVADTVGSIGVLIAGIVTVTTSWPYA---DVVVAVFVALWVLPRAISLARAAL 206
Query: 251 LILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIA 310
IL ++ P HI VD ++ L VEGV VH+ HVW L + + +AH+ + + ++
Sbjct: 207 RILSESSPAHIDVDELKTALCAVEGVTEVHDLHVWTLVPGKDVVTAHL--TSARDSARVL 264
Query: 311 EKVKEFFHNEGIHSTTIQPE 330
+ + G+ T+Q E
Sbjct: 265 DDARAVLAARGLDHATVQVE 284
>UniRef50_Q99726 Cluster: Zinc transporter 3; n=23; Mammalia|Rep:
Zinc transporter 3 - Homo sapiens (Human)
Length = 388
Score = 66.5 bits (155), Expect = 1e-09
Identities = 40/145 (27%), Positives = 71/145 (48%), Gaps = 3/145 (2%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
G+ +++ F+HVL D L S V+ ++++++ +YK DP P L
Sbjct: 228 GNTSVRAAFVHVLGDLLQSFGVLAASILIYFKP-QYKA-ADPISTFLFSICALGSTAPTL 285
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSE- 305
R+ IL++ P ++ + ++ L +V GV A HE H+W L +ASAH+ + ++
Sbjct: 286 RDVLRILMEGTPRNVGFEPVRDTLLSVPGVRATHELHLWALTLTYHVASAHLAIDSTADP 345
Query: 306 YMKIAEKVKEFFHNEGIHSTTIQPE 330
+AE + G S T+Q E
Sbjct: 346 EAVLAEASSRLYSRFGFSSCTLQVE 370
Score = 56.8 bits (131), Expect = 8e-07
Identities = 27/76 (35%), Positives = 49/76 (64%), Gaps = 3/76 (3%)
Query: 13 CMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFG 71
C +C F E++ GY+ +S+A++ D+ H+L+DV +++ + S+ +S + ++ TFG
Sbjct: 80 CAVCFV--FMAGEVVGGYLAHSLAIMTDAAHLLADVGSMMGSLFSLWLSTRPATRTMTFG 137
Query: 72 WARAEVLGALVNAVFL 87
W R+E LGAL + V L
Sbjct: 138 WHRSETLGALASVVSL 153
>UniRef50_UPI0000E4799B Cluster: PREDICTED: similar to zinc
transporter ZnT-2; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to zinc transporter
ZnT-2 - Strongylocentrotus purpuratus
Length = 379
Score = 66.1 bits (154), Expect = 1e-09
Identities = 36/98 (36%), Positives = 57/98 (58%), Gaps = 1/98 (1%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
+G K RL+ LCL E++ ++ S+A+VAD+ H+L+DV II+ S+ ++ K
Sbjct: 37 NGAKARLIFALCLCMLIVIAEIVGSILSGSLAIVADAGHLLTDVVTYIISLTSIWLAKKP 96
Query: 65 WSKN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
SK T+G RAEV+GAL + + + L +T A R
Sbjct: 97 PSKKFTYGLLRAEVVGALFSIILSICLAVVLTYFAALR 134
Score = 58.8 bits (136), Expect = 2e-07
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 4/112 (3%)
Query: 188 HMNMKGVFLHVLSDAL-GSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
HMN++ LH+ D+L G ++V + ++ + E K +DP + L
Sbjct: 216 HMNVRAACLHIFGDSLFGFGLLVAALIIYFKPELKI---LDPILTIIFGFIVLGTLFGLF 272
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ES IL+ PT + D +RRL ++GV VH +W L D + H+
Sbjct: 273 KESIHILMAGKPTGVDYDEAKRRLVEIDGVEGVHSLRIWSLTSDVPLVCVHL 324
>UniRef50_UPI0000499414 Cluster: cation efflux protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: cation efflux
protein - Entamoeba histolytica HM-1:IMSS
Length = 543
Score = 66.1 bits (154), Expect = 1e-09
Identities = 33/100 (33%), Positives = 58/100 (58%), Gaps = 5/100 (5%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
K +L + F FVE+ G+ + S+ L++D FHML D AL + ++ ++ +W+
Sbjct: 249 KSRKLFYYFLINLAFMFVEVAYGWWSGSLGLISDGFHMLFDCVALAMGLVATVIA--RWA 306
Query: 67 KN---TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
+ T+G+ R+E L VNA+FLV + F + +E++ R I
Sbjct: 307 PDRLFTYGYGRSETLSGFVNALFLVYIAFFVLLESIHRLI 346
Score = 64.5 bits (150), Expect = 4e-09
Identities = 37/109 (33%), Positives = 58/109 (53%), Gaps = 3/109 (2%)
Query: 190 NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRES 249
NM+G+FLHVLSD LGS+ V+ S+ +V W DP PLL+ S
Sbjct: 404 NMEGIFLHVLSDTLGSVGVIISSYLVEYFGWVIS---DPICSLCLSAMIFCSVLPLLKNS 460
Query: 250 SLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ +LLQ+VP D I+ +L + GV V + ++W+ + ++A+ I
Sbjct: 461 ASMLLQSVPKGYDDDLIKSKLNQIAGVKDVIKLNLWEFSESCLVATTVI 509
>UniRef50_Q1ZSN3 Cluster: Cation diffusion facilitator family
transporter; n=1; Vibrio angustum S14|Rep: Cation
diffusion facilitator family transporter - Vibrio
angustum S14
Length = 301
Score = 66.1 bits (154), Expect = 1e-09
Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+NMKG FLH+ DA SL V+ +A ++ +T W + +D W LL++
Sbjct: 145 LNMKGAFLHMAGDAAVSLGVIITAFIINITGWDW---LDSATSLAIVVVILIGTWGLLKD 201
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
S L VP+++ + ++ L + V H+ HVW ++ + H+ +
Sbjct: 202 SINYSLDAVPSNVDMVGLKAYLAALPNVATFHDLHVWPMSTTENAMTVHLVVDEYDKGQG 261
Query: 309 IAEKVKEFFHNE-GIHSTTIQPE 330
+ +++K + H+ I T+Q E
Sbjct: 262 MPDEIKHYVHDHFEIEHVTVQIE 284
Score = 56.4 bits (130), Expect = 1e-06
Identities = 31/85 (36%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNTFGWARAEVLG 79
+ VE G+IT+S+AL+AD+ H LSDV L +A+ + ++ K + T+G+ + +L
Sbjct: 26 YVIVEATYGFITDSLALLADAGHNLSDVVTLALAWGAFVLAKKAATEQRTYGFRKVTILA 85
Query: 80 ALVNAVFLVALCFSITVEAVKRFIE 104
+L +A+ L+ +I EAV RF E
Sbjct: 86 SLTSALLLLFALGAIAWEAVLRFSE 110
>UniRef50_Q57YU8 Cluster: Metal-ion transporter, putative; n=4;
Trypanosoma|Rep: Metal-ion transporter, putative -
Trypanosoma brucei
Length = 471
Score = 66.1 bits (154), Expect = 1e-09
Identities = 50/196 (25%), Positives = 86/196 (43%), Gaps = 14/196 (7%)
Query: 148 NSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLI 207
+S + GHN + + ++ + H S S G + LH L D + SL
Sbjct: 263 DSLCEENTGHNHSHDHGHGHGHSGSEGEGHDHSHSHSGRGFA-VHAALLHALGDCVQSLG 321
Query: 208 VVGSALVVWLTE--------WKYKHY--IDPXXXXXXXXXXXXXXWPLLRESSLILLQTV 257
V+ + + +++ ++Y Y DP PLLR+ IL+++
Sbjct: 322 VILAGIFIYVANRYSYGVPSYRYSIYNLADPLCSLLFAVITLNMTRPLLRDLLGILMEST 381
Query: 258 PTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFF 317
P I + L++++GV VH+ HVW +A D S H+ + ++ A++V + F
Sbjct: 382 PPGINYSELLSALRSIKGVEGVHDLHVWSIASDYAALSVHLEADDKDAALQEAQEVCKRF 441
Query: 318 HNEGIHSTTIQPEFVE 333
GI TTIQ + VE
Sbjct: 442 ---GITHTTIQVDTVE 454
Score = 63.7 bits (148), Expect = 7e-09
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Query: 3 RYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP 62
R+ K M C F VEL+ G + +S+AL+ D+ H+L DV A ++ +S++ +
Sbjct: 57 RHESKVLLAALMFCFV--FMLVELMFGVVAHSLALLTDASHLLIDVGAYALSIMSLRAAS 114
Query: 63 K-KWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
+ K ++GW RAEV+G LV+ + AL I +E + R
Sbjct: 115 RTSCGKYSYGWHRAEVIGTLVSVFSIWALVVWIVMEGLDR 154
>UniRef50_UPI00006CA446 Cluster: cation diffusion facilitator family
transporter containing protein; n=1; Tetrahymena
thermophila SB210|Rep: cation diffusion facilitator
family transporter containing protein - Tetrahymena
thermophila SB210
Length = 549
Score = 65.7 bits (153), Expect = 2e-09
Identities = 49/191 (25%), Positives = 91/191 (47%), Gaps = 7/191 (3%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLG 79
F E++ G I+ S+A+++D+ HM SD++ I+ ++V +S K SK+ +FG+ R+EV+G
Sbjct: 61 FLVAEIVGGVISGSLAILSDAAHMFSDLSGFFISIVAVWISSKPASKSLSFGYHRSEVIG 120
Query: 80 ALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXXXXXHVPPPSN 139
AL++ + + + + EA R + E + P H P +
Sbjct: 121 ALISIILIWIVTIILLYEATIRIVNKEPVEQPVYMLATAVFGLICNLIMAKVLH-SGPGH 179
Query: 140 VRHLTEIVNSNADRALGHNST---DNEETDEMVK-KAKTQNHKSCKSSSDPGHMNMKGVF 195
H +S++ GHN D+ +T+ K + + Q+ ++ K S GH + V
Sbjct: 180 SHHGCSHGHSHS-HGDGHNHNHDHDHGDTNHKHKHEGEHQHEQNHKKSHCSGHQHEHKVH 238
Query: 196 LHVLSDALGSL 206
H D + +L
Sbjct: 239 DHKNYDNMKAL 249
Score = 64.9 bits (151), Expect = 3e-09
Identities = 46/188 (24%), Positives = 81/188 (43%), Gaps = 13/188 (6%)
Query: 148 NSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLI 207
N N D H+ +N + D K K + K + N++ +HVL D L S+
Sbjct: 351 NHNQDHNHDHDHDNNHKHDSQQDKKKNISQVEAKDN-----YNLRAAMIHVLGDLLQSIG 405
Query: 208 VVGSALVVWLTE----WKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQV 263
V+ +A +++ + Y H DP + + +L++ P+ I V
Sbjct: 406 VLIAAFLIYFLGGDDGFNYWHLADPICTYIFSILVLLTTKNVSIDCFKVLMEGTPSQIDV 465
Query: 264 DAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEY-MKIAEKVKEFFHNEGI 322
+ +L + VM +H+ H+WQL+ + + HI +SE ++ K E GI
Sbjct: 466 QNFKEKLLKIANVMEIHDLHIWQLSQGKPSLTCHI---FISENPREVLNKTTELCRQYGI 522
Query: 323 HSTTIQPE 330
+ +TIQ E
Sbjct: 523 YHSTIQIE 530
>UniRef50_Q8G4R7 Cluster: Probable cation efflux protein; n=4;
Bifidobacterium|Rep: Probable cation efflux protein -
Bifidobacterium longum
Length = 312
Score = 65.3 bits (152), Expect = 2e-09
Identities = 35/93 (37%), Positives = 55/93 (59%), Gaps = 1/93 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFL-SVKMSPKKWSKN 68
RL+ L +TG F +E++ +T S+AL+ D+ HML+D++ L + + ++ M K +
Sbjct: 21 RLIATLTVTGSVFLIEVVSAVLTGSLALLVDAGHMLTDMSVLAASTITAILMRRKPSNTR 80
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
T+GWAR EVL A AV L+ + VEA R
Sbjct: 81 TWGWARLEVLTAAAGAVVLLIVGIYALVEAGMR 113
Score = 64.5 bits (150), Expect = 4e-09
Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 3/117 (2%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
+S +MNMK FL V++DALGS+ VV SALV+ T W + D
Sbjct: 147 ASQREDNMNMKAAFLEVMNDALGSVAVVASALVMIPTGW---NGFDAVAGAVIALMMIPR 203
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
LL + +LL+ P + +D ++ L++V V+AVH+ H ++ I AH+
Sbjct: 204 AIKLLHNAVKVLLEETPDGLDLDKVREHLEDVPHVLAVHDLHASTVSTGMPILMAHV 260
>UniRef50_Q7NDR3 Cluster: Gll4169 protein; n=3; Bacteria|Rep:
Gll4169 protein - Gloeobacter violaceus
Length = 303
Score = 64.9 bits (151), Expect = 3e-09
Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 3/110 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++G FLH+ SDA SL V + + LT W + +DP W LL +
Sbjct: 148 LNVRGAFLHLASDAAVSLGTVFAGAAILLTGWAW---LDPVVSLVIGVVIVVGTWGLLVD 204
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
S + L VP I + ++ L+++ GV VH+ H+W ++ +AH+
Sbjct: 205 SLNLALDAVPEGIDPEVVKAYLQSLRGVGEVHDLHIWAMSTTETALTAHL 254
Score = 58.4 bits (135), Expect = 3e-07
Identities = 34/88 (38%), Positives = 51/88 (57%), Gaps = 1/88 (1%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAF-LSVKMSPKKWSKNTFGWA 73
+ L GF +E + G + S+AL+AD+ H LSDV L +A+ SV + + T+G
Sbjct: 24 IALNVGFVVIEAVYGILAGSLALLADAGHNLSDVLGLALAWGASVLTTRHPSPRRTYGLR 83
Query: 74 RAEVLGALVNAVFLVALCFSITVEAVKR 101
R+ +L AL+NAV L+ +I EAV R
Sbjct: 84 RSSILAALLNAVTLLVAVGAIAWEAVIR 111
>UniRef50_Q30S31 Cluster: Cation efflux protein; n=1; Thiomicrospira
denitrificans ATCC 33889|Rep: Cation efflux protein -
Thiomicrospira denitrificans (strain ATCC 33889 / DSM
1351)
Length = 303
Score = 64.9 bits (151), Expect = 3e-09
Identities = 39/107 (36%), Positives = 59/107 (55%), Gaps = 2/107 (1%)
Query: 7 KKCRLLCMLCLTGGFFFV-ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW 65
KK ++L + F V E+ G + SMAL+AD+ H L DV AL I+ ++V KK
Sbjct: 6 KKNKILKKVIFLNIFLVVAEIFAGIYSGSMALLADALHNLGDVLALFISLVAVVYGTKKA 65
Query: 66 SK-NTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
TFG+ +AE++ A VN++FLV I +E+++R I P
Sbjct: 66 DDFMTFGYIKAEMMAAFVNSIFLVITMLFILLESIERLFTPNSIDAP 112
Score = 58.8 bits (136), Expect = 2e-07
Identities = 47/154 (30%), Positives = 76/154 (49%), Gaps = 12/154 (7%)
Query: 185 DPGHMNMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXW 243
D MNMK +LH+LSDA+ S + VG L+ + ID +
Sbjct: 146 DHEDMNMKSAYLHMLSDAVISFSVAVGGVLIYFFGIVA----IDSILSILFSIYIILETY 201
Query: 244 PLLRESSLILLQTVPTHI-QVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN 302
PLL++S L+ + I +V+AI + + V+++H+ H+++ + S HI +N
Sbjct: 202 PLLKKSFYSLMDSNVDDIKEVEAI---ILCFDEVLSIHDLHLYRPSSREFYGSVHIVFKN 258
Query: 303 ---LSEYMKIAEKVKEFFHNEGIHSTTIQPEFVE 333
LSE K++ ++E +EGI IQPE VE
Sbjct: 259 DLLLSEVDKLSNLIRERLCDEGITHFVIQPESVE 292
>UniRef50_Q2GIB0 Cluster: Cation efflux family protein; n=1;
Anaplasma phagocytophilum HZ|Rep: Cation efflux family
protein - Anaplasma phagocytophilum (strain HZ)
Length = 301
Score = 64.5 bits (150), Expect = 4e-09
Identities = 38/152 (25%), Positives = 76/152 (50%), Gaps = 9/152 (5%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++N++ LHV+ D L S+ + S++++ + W+ IDP + +++
Sbjct: 148 NLNIRSAVLHVIGDLLCSVAAIASSIIIRFSGWQ---IIDPMLSLLVSTVMLISAFSIVK 204
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKN-VEGVMAVHEFHVWQLAGDRIIASAHIR--C--RN 302
SS ILL+ P +I V +QR + + + V+ VH H+W L + I + H+R C +
Sbjct: 205 NSSNILLEGKPYNIDVGELQRNITSAIPNVIDVHHVHLWSLTAEYPIMTMHVRIACGSSD 264
Query: 303 LSEYMKIAEKVKEFFHNE-GIHSTTIQPEFVE 333
++ +++ + +K+ I TI+ E E
Sbjct: 265 VASSVQVVKSIKKLLQERFSISHVTIEIEHEE 296
Score = 60.9 bits (141), Expect = 5e-08
Identities = 27/101 (26%), Positives = 61/101 (60%), Gaps = 1/101 (0%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKN 68
R++ + + VE I G++++S+ L++D+ H+ D+ ALI++F + +++ K+ +
Sbjct: 19 RMVMAIVVVACTLVVETIGGFVSHSLVLLSDAGHVFIDLVALILSFAAYRLATKEADEQR 78
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
++G+ R +V+ A VN + + I +E++KRF+ +H
Sbjct: 79 SYGYHRFQVMAAFVNGISWFVIAALIVIESIKRFVNPVEVH 119
>UniRef50_Q5B283 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 841
Score = 64.5 bits (150), Expect = 4e-09
Identities = 33/103 (32%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNT 69
R+ + L GF V+L G+ T S+ L++DS HM D AL++ + MS KW +T
Sbjct: 465 RIFYFMSLNFGFMLVQLSYGFATGSLGLLSDSIHMFFDCLALVVGLCAAVMS--KWPPST 522
Query: 70 ---FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
+G+ + + L N +FL+ + I EAV+R +H
Sbjct: 523 RFPYGYGKVDTLSGFANGIFLMIISVEIIYEAVERLSSGSQMH 565
Score = 47.2 bits (107), Expect = 6e-04
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 4/97 (4%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
S G+ NM G+FLH+L+D LGS+ VV S ++V + W DP
Sbjct: 607 SHSHGNENMHGIFLHILADTLGSVAVVISTILVHYSGWA---GYDPIASCMIAILIFASA 663
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAV 279
PL+ ++ LL T+P ++ + ++ L V + V
Sbjct: 664 VPLVSSTAKSLLLTLPADVEYN-VRETLAGVSTLRGV 699
>UniRef50_UPI0000D5546C Cluster: PREDICTED: similar to solute
carrier family 30, member 2 isoform 1; n=2;
Endopterygota|Rep: PREDICTED: similar to solute carrier
family 30, member 2 isoform 1 - Tribolium castaneum
Length = 429
Score = 64.1 bits (149), Expect = 5e-09
Identities = 33/118 (27%), Positives = 60/118 (50%), Gaps = 4/118 (3%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTE-WKYKHYIDPXXXXXXXXXXXX 240
S+ ++N++ F+HV+ D L S V +A V++ E W IDP
Sbjct: 208 STHSHDNINVRAAFIHVIGDFLQSFGVFVAAAVIYFNEQWVI---IDPICTFIFSVLVMF 264
Query: 241 XXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ +++++ +L++ P I + + + L N+EGV VH +W L+ D+I SAH+
Sbjct: 265 TTFNIIKDTLTVLMEGAPKGIDFNQVMKTLLNIEGVKRVHNLRIWGLSLDKIAMSAHV 322
Score = 63.7 bits (148), Expect = 7e-09
Identities = 34/102 (33%), Positives = 63/102 (61%), Gaps = 3/102 (2%)
Query: 3 RYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP 62
R + +K + +LC+ F E+I GY++NS+A+ +D+ H+L+D A+ +I+ ++ M+
Sbjct: 69 RKARRKLIVASVLCVL--FMIGEVIGGYLSNSLAIASDAAHLLTDFASFMISLFALWMAT 126
Query: 63 KKWSKNT-FGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
+ +K FGW RAEV+GAL + + + + + AV+R I
Sbjct: 127 RPSTKTMHFGWYRAEVIGALTSVLLIWVVTGILVYIAVQRVI 168
>UniRef50_UPI00006CBB53 Cluster: cation diffusion facilitator family
transporter containing protein; n=1; Tetrahymena
thermophila SB210|Rep: cation diffusion facilitator
family transporter containing protein - Tetrahymena
thermophila SB210
Length = 525
Score = 64.1 bits (149), Expect = 5e-09
Identities = 33/107 (30%), Positives = 60/107 (56%), Gaps = 1/107 (0%)
Query: 6 GKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW 65
G C+L + F E++ G I+ S+A+++D+ HM SD++ I+ +S+ + +
Sbjct: 98 GVLCKLFVASAIALIFLIAEVVGGIISGSLAILSDAAHMFSDLSGFFISIMSIWIGTRPA 157
Query: 66 SKN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNP 111
SK ++G+ RAEV+GAL + V + L + EA R I ++ +P
Sbjct: 158 SKKLSYGYHRAEVIGALGSIVLIWGLTIVLLYEATDRIINKSMVTDP 204
Score = 63.7 bits (148), Expect = 7e-09
Identities = 42/199 (21%), Positives = 88/199 (44%), Gaps = 7/199 (3%)
Query: 148 NSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSS-SDPGHMNMKGVFLHVLSDALGSL 206
N + D H+ + + D Q K S+ ++ + N++ +HV+ D + S+
Sbjct: 321 NHDHDHDHNHDHDHDHDHDHDHDHGNGQKKKKNLSNINEHENYNLRAAMIHVIGDIIQSI 380
Query: 207 IVVGSALVVWL----TEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQ 262
VV +AL+++ E+ Y H DP ++++ +L++ P I+
Sbjct: 381 GVVVAALLIYFYANTDEYDYWHLADPICTYLFSILVLFTTVKIVKDCITVLMEGTPQDIE 440
Query: 263 VDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFHNEGI 322
+ + +L ++ V+ +H+ H+W L+ + S HI E ++ + + GI
Sbjct: 441 IKDFKDQLLAIDKVVQIHDLHIWSLSIGKPSMSVHIFVNGDKE--QVLREATKICRQHGI 498
Query: 323 HSTTIQPEFVEGPQDENEV 341
+ +TIQ E E + N +
Sbjct: 499 YHSTIQIEDWESRELPNSI 517
>UniRef50_A0AW44 Cluster: Cation diffusion facilitator family
transporter; n=13; Actinobacteria (class)|Rep: Cation
diffusion facilitator family transporter - Arthrobacter
sp. (strain FB24)
Length = 305
Score = 64.1 bits (149), Expect = 5e-09
Identities = 32/101 (31%), Positives = 59/101 (58%), Gaps = 1/101 (0%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK- 63
+G + +L+ + +T E+I +T S+AL+AD+ HM +D L+IA ++ ++ K
Sbjct: 13 AGNRSKLILVFVITFTVMIAEIIGSVLTGSLALLADAGHMFTDSTGLLIALIAASLALKP 72
Query: 64 KWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+K T+G+ RAE++ A A L+ + + VE ++R IE
Sbjct: 73 ATAKRTWGYKRAEIIAAAGQAALLLGVGGFVIVEGIRRLIE 113
Score = 54.8 bits (126), Expect = 3e-06
Identities = 30/111 (27%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
+ NMK FL VL+DALGS+ V+ +A+++ +T W D LLR
Sbjct: 147 NFNMKAAFLEVLNDALGSVAVIVAAIIIAVTGWV---QADAVVSLLIGVLIIPRTLKLLR 203
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
++ +L++ P + + ++ + + V+ VH+ H +A + SAH+
Sbjct: 204 DTVNVLMENAPQGLDMALVREHILALPHVIDVHDLHASLVASGTPVLSAHV 254
>UniRef50_Q8TRQ7 Cluster: Cation efflux system protein; n=2;
Methanosarcina|Rep: Cation efflux system protein -
Methanosarcina acetivorans
Length = 291
Score = 64.1 bits (149), Expect = 5e-09
Identities = 37/143 (25%), Positives = 72/143 (50%), Gaps = 5/143 (3%)
Query: 190 NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRES 249
N K + H+L D LG ++++ ++++ W + IDP + +E+
Sbjct: 136 NEKILSWHLLEDILGWVVLLIGSVIIGF--WN-QPIIDPIMTIGFTIFVLWGVFKNAKET 192
Query: 250 SLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRN--LSEYM 307
+LL+ VP +I +D ++ + +VEG AVH+ H+W L G+ I +AH+ + L+
Sbjct: 193 FNLLLEGVPEYIDIDEVKESILSVEGTKAVHDLHIWSLEGETDILTAHVVVEDEYLARPD 252
Query: 308 KIAEKVKEFFHNEGIHSTTIQPE 330
K+ + +K I +T++ E
Sbjct: 253 KMRQSIKSRLEKHQIEHSTLELE 275
Score = 61.7 bits (143), Expect = 3e-08
Identities = 34/90 (37%), Positives = 53/90 (58%), Gaps = 1/90 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNTFGWARAEVLG 79
F +ELI G +TNS+AL+AD+ H +D ALI+A+ + K + K SK TFG+ R +L
Sbjct: 18 FTIIELIGGILTNSLALLADAMHDFADSLALIVAWFAEKKAKKPATSKMTFGYRRLSLLS 77
Query: 80 ALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
A + L+A I +A+ R + E ++
Sbjct: 78 AAFATIVLIAGSLFILSQAIPRLLNPEPVN 107
>UniRef50_Q9BRI3 Cluster: Zinc transporter 2; n=34; Eumetazoa|Rep:
Zinc transporter 2 - Homo sapiens (Human)
Length = 323
Score = 64.1 bits (149), Expect = 5e-09
Identities = 37/155 (23%), Positives = 73/155 (47%), Gaps = 3/155 (1%)
Query: 177 HKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXX 236
H ++ + +++ F+HV+ D + S+ V+ +A +++ +YK Y+DP
Sbjct: 154 HSHGTTNQQEENPSVRAAFIHVIGDFMQSMGVLVAAYILYFKP-EYK-YVDPICTFVFSI 211
Query: 237 XXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASA 296
+LR+ L+L++ P + A++ L +VEGV A+H H+W L + + S
Sbjct: 212 LVLGTTLTILRDVILVLMEGTPKGVDFTAVRDLLLSVEGVEALHSLHIWALTVAQPVLSV 271
Query: 297 HIRCRNLSEYMKIAEKVKEFFHNE-GIHSTTIQPE 330
HI ++ + + + H+ TIQ E
Sbjct: 272 HIAIAQNTDAQAVLKTASSRLQGKFHFHTVTIQIE 306
>UniRef50_UPI0000D56740 Cluster: PREDICTED: similar to T18D3.3; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to T18D3.3 -
Tribolium castaneum
Length = 337
Score = 63.7 bits (148), Expect = 7e-09
Identities = 36/101 (35%), Positives = 59/101 (58%), Gaps = 3/101 (2%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
KK + +LC F ELI G+I S+A++ D+ H+ SD +I+ LS+ ++ K +
Sbjct: 77 KKLLIAAILCFF--FMITELIGGFIAGSLAVMTDAAHLFSDFIGFLISLLSIWVARKAPT 134
Query: 67 KN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFE 106
+N TFG+ RAEVLGA ++ + + L V A+ R ++ E
Sbjct: 135 RNMTFGYYRAEVLGAFLSVLTVWLLAGVFAVLAINRLLKKE 175
Score = 43.6 bits (98), Expect = 0.008
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 4/123 (3%)
Query: 176 NHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXX 235
NH S ++N++ HVL D L SL V+ +++++ + + DP
Sbjct: 207 NHSHGLSDQSNSNINVRAAAAHVLGDLLQSLGVLIASIIIKV--FPSAKVADPICTLIFS 264
Query: 236 XXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIAS 295
+ ++S +LL+ P H A + L N+ V +H H+W L+ + S
Sbjct: 265 AVVIFTTAKVAKDSIWLLLEGSPKHSGDLAFE--LLNISNVRHLHNLHIWALSPGKDAVS 322
Query: 296 AHI 298
H+
Sbjct: 323 VHL 325
>UniRef50_Q4REH2 Cluster: Chromosome 10 SCAF15123, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 10
SCAF15123, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 368
Score = 63.7 bits (148), Expect = 7e-09
Identities = 34/145 (23%), Positives = 68/145 (46%), Gaps = 3/145 (2%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
G+ +++ F+HV+ D + S+ V+ +A+V+ W DP +P+
Sbjct: 221 GNASVRAAFVHVVGDLVQSVGVLLAAVVIHF--WPEYKAADPICTFLFSALVLGTTFPVA 278
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEY 306
++ IL++ P + D+++++L +V GV VH HVW L + + S H+ ++
Sbjct: 279 KDVFRILMEGAPRDVCADSVRKQLLSVRGVADVHRLHVWSLNATQPLLSVHVTAEEEADA 338
Query: 307 MKIAEKVKEFFHNE-GIHSTTIQPE 330
+ V + +E T+Q E
Sbjct: 339 RMVLTNVTKLLRSEFSFSDVTVQVE 363
Score = 57.6 bits (133), Expect = 5e-07
Identities = 30/90 (33%), Positives = 55/90 (61%), Gaps = 3/90 (3%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNTFGWARAEVLG 79
F E+I GY S+A++ D+ H+L+D ++ I+ S+ +S + TFGW RAE+LG
Sbjct: 84 FMAGEMIGGYAARSLAIMTDAAHLLTDFGSIAISLFSLWLSSRPPTGVMTFGWHRAEILG 143
Query: 80 ALVNAVFLVALCFSITVEAVKRFI--EFEV 107
L++ V + A+ ++ + A +R + ++EV
Sbjct: 144 MLLSVVSIWAVTAALVLSAGQRLVHGDYEV 173
>UniRef50_A7B9C7 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 343
Score = 63.7 bits (148), Expect = 7e-09
Identities = 33/95 (34%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVK-MSPKKWSKN 68
RL L +TG EL+ + + S++L AD+ HM+ D + L+IA ++ + M + K+
Sbjct: 59 RLGWALTVTGAIVVAELVGAFWSGSLSLAADAGHMVVDASGLVIALIAARLMRRPRDEKH 118
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
T+GWAR+EVL A + A L+ +C + E R +
Sbjct: 119 TWGWARSEVLAATLQAGMLLIICAIVAWEGAWRLL 153
Score = 63.3 bits (147), Expect = 9e-09
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++NMK FL V +DALGS+ V+ +A W W D LLR
Sbjct: 188 NLNMKAAFLEVANDALGSVAVIVAAGAEWAFGWTRA---DAIASLLIAALMAPRALTLLR 244
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
S IL++ P ++ V ++ + +V+GV+ VH+ HV ++ + +AH+
Sbjct: 245 RSVAILMEQAPANVDVTELRAHMLDVDGVLDVHDLHVAAVSSHLVTVTAHV 295
>UniRef50_Q4DHZ0 Cluster: Zinc transporter, putative; n=2;
Trypanosoma cruzi|Rep: Zinc transporter, putative -
Trypanosoma cruzi
Length = 416
Score = 63.7 bits (148), Expect = 7e-09
Identities = 37/83 (44%), Positives = 51/83 (61%), Gaps = 5/83 (6%)
Query: 24 VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK---NTFGWARAEVLGA 80
VE I G+I NS+A+++D+ HML+DV AL I+ +V S WS NT+GW R EV+GA
Sbjct: 47 VEGICGFIANSLAVLSDAVHMLADVFALSISLFAVYAS--SWSATTINTYGWGRVEVVGA 104
Query: 81 LVNAVFLVALCFSITVEAVKRFI 103
L + + L I A+KR I
Sbjct: 105 LCSILTTWGLAAWIVFGAIKRTI 127
Score = 60.1 bits (139), Expect = 9e-08
Identities = 40/155 (25%), Positives = 66/155 (42%), Gaps = 13/155 (8%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWK----------YKHYIDPXXXXXXXX 236
G MN++ LHV D + +L VV +A V+W K Y + DP
Sbjct: 249 GSMNLRAAMLHVFGDCIQALGVVVAASVIWFGNLKTQGSARSANSYYNLADPFFSFLFGL 308
Query: 237 XXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASA 296
L +E +LL+ VP + D+++ L VE V + + H+W + + + SA
Sbjct: 309 ITIYTTRDLFKEVVSVLLEEVPASVSYDSVRDVLLGVENVERIDDLHMWSVGPNFHLLSA 368
Query: 297 HIR---CRNLSEYMKIAEKVKEFFHNEGIHSTTIQ 328
H+ C + E ++ E+ G+ TIQ
Sbjct: 369 HLTVAGCSTIREAKELVEEAAGRCKRLGLAHATIQ 403
>UniRef50_Q9CCX3 Cluster: Putative cation-efflux transporter
component; n=2; Mycobacterium leprae|Rep: Putative
cation-efflux transporter component - Mycobacterium
leprae
Length = 268
Score = 62.9 bits (146), Expect = 1e-08
Identities = 33/97 (34%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS--K 67
R++ + FF VEL + + NS+ L+AD+ HML+DV A+ + ++ ++ S
Sbjct: 32 RMIVAAAILMVFFGVELTIALLINSITLLADAGHMLTDVVAVFMGLAALVLAKHGHSAPN 91
Query: 68 NTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+ W RAEV A+ NA L+ + I EA++RF E
Sbjct: 92 RPYSWHRAEVFTAMANAALLIGVATFILYEAIRRFKE 128
>UniRef50_A3XEG4 Cluster: Cation efflux system protein; n=9;
Proteobacteria|Rep: Cation efflux system protein -
Roseobacter sp. MED193
Length = 305
Score = 62.9 bits (146), Expect = 1e-08
Identities = 44/163 (26%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
S G +N++ +FLH LSDAL S+ ++VG L++ L + + ++DP
Sbjct: 142 SMQKGSVNIRALFLHNLSDALASVAVIVGGTLII-LYDMR---WVDPAITIGIALYILYL 197
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR 301
+ + L+ P I + + R ++ V+GV+ VH H+WQ+ + HI
Sbjct: 198 SFTEIGAPIRTLMLGSPPDIDGNDVVRAIQIVDGVVDVHHVHLWQMQENAAALDCHIVVE 257
Query: 302 --NLSEYMKIAEKVKEFFHNE-GIHSTTIQPEFVEGPQDENEV 341
+ E KI E VK H I +T++ E + E +V
Sbjct: 258 RDRMGEADKIKENVKSVLHERFSIEHSTLEFEATDNAHQEAQV 300
Score = 61.3 bits (142), Expect = 4e-08
Identities = 30/96 (31%), Positives = 56/96 (58%), Gaps = 1/96 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
R+ + G +++ G ++ S+AL+AD+ H SD+A+L+IAF + K++ + +
Sbjct: 18 RVAIAIWANGLLTVAQIVGGILSGSLALIADALHNFSDMASLVIAFAARKIARRPADERM 77
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
TFG+ R E++ AL+N L+ + F + E R I+
Sbjct: 78 TFGYGRVEIVAALINYTTLIVIGFYLIYEGGMRMID 113
>UniRef50_A3ETR2 Cluster: Co/Zn/Cd efflux system component; n=4;
Bacteria|Rep: Co/Zn/Cd efflux system component -
Leptospirillum sp. Group II UBA
Length = 335
Score = 62.9 bits (146), Expect = 1e-08
Identities = 33/94 (35%), Positives = 56/94 (59%), Gaps = 1/94 (1%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNT 69
L L L F VE++ G +S+AL++D+ HML+D A+ ++ ++++ + + T
Sbjct: 43 LTIALALLLAFMAVEVVAGLKASSLALISDAGHMLTDAGAIAMSLAVMRLAQRPAGGRFT 102
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
FG+ RAE+ A +N + LVAL +EAV+R I
Sbjct: 103 FGFKRAEIFSAQINGLTLVALAGWFLIEAVRRLI 136
Score = 54.4 bits (125), Expect = 4e-06
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 3/117 (2%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
S ++ +N++G F H+L+D ++ +A+ L W + + D
Sbjct: 165 SKANRESLNVEGSFQHILTDLYAFIV---TAIAGALIHWTHFYRFDALAALVVAALMLRA 221
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
LL+ES + L++ P + D I L GV VH+ HVW++ SAH+
Sbjct: 222 GVGLLKESGRVFLESAPKGVDSDVIGDTLAADPGVCEVHDLHVWEVTSGFTALSAHV 278
>UniRef50_Q7PWF8 Cluster: ENSANGP00000019448; n=3; Culicidae|Rep:
ENSANGP00000019448 - Anopheles gambiae str. PEST
Length = 398
Score = 62.9 bits (146), Expect = 1e-08
Identities = 33/99 (33%), Positives = 59/99 (59%), Gaps = 1/99 (1%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW- 65
+K +L+ T F E + GY++ S+A++ D+ H+LSD + +IA +S+ +S +
Sbjct: 67 EKRKLMWATLFTVAFMTAEFVGGYLSGSLAIMTDAAHLLSDCISFVIAIISIWISNRPAD 126
Query: 66 SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
++ +FG+ R EVLGAL++ + AL + V + R IE
Sbjct: 127 TRMSFGYRRVEVLGALLSIFGIWALTAVLVVMSANRLIE 165
Score = 51.6 bits (118), Expect = 3e-05
Identities = 27/120 (22%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
Query: 179 SCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXX 238
S ++S ++N++ +HV+ D + S+ V+ +A+V+ + DP
Sbjct: 279 SRQNSRHNSNLNVRAAIIHVIGDFIQSIGVLVAAIVIKFAP--HLKAFDPICTFVFSLIV 336
Query: 239 XXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ R+S IL+ VP + ++ + L +EGV VH+ VW ++ + + H+
Sbjct: 337 LITTVRIFRDSMRILVDAVPVDVSLERLSAELAYIEGVKTVHDLRVWSVSTGWNVMTVHL 396
>UniRef50_Q6ICY4 Cluster: Metal tolerance protein C2; n=7;
Magnoliophyta|Rep: Metal tolerance protein C2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 393
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/101 (34%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
RL ++ L + EL +G T + LV+D+FH+ L + ++ S KK
Sbjct: 113 RLFLLIALNVLYSTTELSIGIFTGRVGLVSDAFHLTFGCGLLTFSLFAMATSRKKPDHAY 172
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
++G+ R EVL A NA+FL+ + FS+ VEA+ FI+ E H
Sbjct: 173 SYGYKRLEVLSAFTNALFLMFMSFSLAVEALHAFIQDESEH 213
Score = 46.8 bits (106), Expect = 9e-04
Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 7/146 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
MN V LHV+SD++ S G L WL ++ + PL +
Sbjct: 251 MNYHSVCLHVISDSIRS---AGLILASWLLSLGVEN-AEVLCLGLVSVTVFMLVMPLFKA 306
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNV---EGVMAVHEFHVWQLAGDRIIASAHIRCRNLSE 305
+ +LLQ P +I A+ + L+ + E V V + W++ + S ++ ++ +
Sbjct: 307 TGGVLLQMAPPNIPSSALSKCLRQITSREDVTEVLQARFWEVVPGHTVGSLRLQVKSGID 366
Query: 306 YMKIAEKVKEFFHNEGIHSTTIQPEF 331
+ + V + +H+ G+ T+Q ++
Sbjct: 367 ERPLLQYVYDVYHDLGVQDLTLQTDY 392
>UniRef50_Q5LTM6 Cluster: Cation efflux system protein; n=13;
Alphaproteobacteria|Rep: Cation efflux system protein -
Silicibacter pomeroyi
Length = 320
Score = 62.1 bits (144), Expect = 2e-08
Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Query: 189 MNMKGVFLHVLSDALGSL-IVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
MN++ FLH L+DALGS+ ++V + V+W W + +DP W +
Sbjct: 164 MNIRAAFLHNLADALGSVAVIVAGSAVIWFG-WTW---VDPLVTLMIAAYILWHVWVEIG 219
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ +L+ P + + + R ++ VEGV ++H H+W L + SAH+
Sbjct: 220 AAIGVLMLGTPPGYEPETVAREIEAVEGVQSLHLLHLWSLQENAAALSAHL 270
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/81 (34%), Positives = 53/81 (65%), Gaps = 1/81 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKNTFGWARAEVLGALVN 83
+++ G ++ S+AL+AD+ H SD ALIIAF + +++ + ++ ++G+ RAEV+ AL+N
Sbjct: 49 QVVGGLLSGSLALIADALHNFSDAVALIIAFGARRIARRPADARMSYGYGRAEVIAALIN 108
Query: 84 AVFLVALCFSITVEAVKRFIE 104
L+ L + E + RF++
Sbjct: 109 YTTLIVLALYLVYEGIMRFLD 129
>UniRef50_A0J3Y1 Cluster: Cation diffusion facilitator family
transporter; n=2; Shewanella|Rep: Cation diffusion
facilitator family transporter - Shewanella woodyi ATCC
51908
Length = 330
Score = 62.1 bits (144), Expect = 2e-08
Identities = 69/307 (22%), Positives = 124/307 (40%), Gaps = 36/307 (11%)
Query: 14 MLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN---TF 70
+L LT VE+ G I SMAL+AD +HM + AA +I + + +K + N +F
Sbjct: 31 VLYLTVITMIVEITAGTIYGSMALLADGWHMGTHAAAFMITLFAYYYA-RKHADNPDFSF 89
Query: 71 GWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXXX 130
G + VLG +A+ L + + VE+V + F H +
Sbjct: 90 GTGKVSVLGGFTSAIALGMVALIMLVESV---VRFFSPHQIQFSEAIFVAIIGLTVNLIS 146
Query: 131 XXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMN 190
+ H A GH+ ++E E + + +H N
Sbjct: 147 AVLLKDHHGHSH-----------AHGHHHNEHEHEHEHEHEHEGHDH------------N 183
Query: 191 MKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESS 250
++ ++HVL+DAL S++ + + L +W ++DP W LL ++S
Sbjct: 184 LRAAYMHVLADALTSILAIVALL---FGKWYGLTWLDPLMGVVGSIIITRWAWQLLGQTS 240
Query: 251 LILL-QTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKI 309
ILL +++ ++ + L E V + H+W+++ D A+ I N +
Sbjct: 241 PILLDRSIEDRYRLKITE--LIEAESDHQVADLHIWKVSADHYAAAISIVSHNPKDVEYF 298
Query: 310 AEKVKEF 316
K+ +F
Sbjct: 299 KAKLSDF 305
>UniRef50_Q9V471 Cluster: CG3994-PA, isoform A; n=3; Sophophora|Rep:
CG3994-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 472
Score = 62.1 bits (144), Expect = 2e-08
Identities = 36/171 (21%), Positives = 75/171 (43%), Gaps = 3/171 (1%)
Query: 161 DNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEW 220
D E + + A +H + +MN++ +HV+ D + S+ V +A V++ W
Sbjct: 287 DLEIAAVLAETAPGSHHHGGPVGREAVNMNVRAALIHVIGDVIQSVGVFVAAGVIYF--W 344
Query: 221 KYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVH 280
+DP + +++++ L+L++ P ++ + + + +EGV VH
Sbjct: 345 PEYSIVDPICTFVFSIIVLFTTFTIMKDALLVLMEGTPNYMHYAEVLQIFQGIEGVERVH 404
Query: 281 EFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFFH-NEGIHSTTIQPE 330
+W L+ +++ SAH+ + +I + H TTIQ E
Sbjct: 405 NLRIWALSINKVALSAHLAIAENANPKRILDAATSAVHLRYNFFETTIQIE 455
Score = 58.8 bits (136), Expect = 2e-07
Identities = 34/108 (31%), Positives = 64/108 (59%), Gaps = 5/108 (4%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KW 65
+K + +LCL F E++ G ++NS+A+ D+ H+L+D A+ +I+ ++ ++ +
Sbjct: 89 RKLIIASILCLV--FMIAEIVGGVLSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPST 146
Query: 66 SKNTFGWARAEVLGALVNAVFLVALCFSITV-EAVKRFIEFEVIHNPK 112
+ +FGW RAEV+GA+ +VF++ + I V A+ R I + N K
Sbjct: 147 QRMSFGWYRAEVIGAMA-SVFMIWVITGILVWLAIGRLISGDYEVNAK 193
>UniRef50_Q4WLB1 Cluster: CDF zinc transporter (Msc2), putaitve;
n=7; Eurotiomycetidae|Rep: CDF zinc transporter (Msc2),
putaitve - Aspergillus fumigatus (Sartorya fumigata)
Length = 877
Score = 62.1 bits (144), Expect = 2e-08
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNT 69
R+ + L F V+L G+IT S+ L++DS HM D AL++ + MS KW +
Sbjct: 517 RIFYFMTLNFTFMLVQLSYGFITGSLGLLSDSIHMFFDCLALVVGLCAAVMS--KWPSSA 574
Query: 70 ---FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
+G+ + + L N +FL+ + I EAV+R +H
Sbjct: 575 RFPYGYGKVDTLSGFANGIFLMIISIEIIYEAVERLSSGSQMH 617
Score = 47.2 bits (107), Expect = 6e-04
Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
S G+ NM G+FLH+L+D LGS+ VV S ++V + W DP
Sbjct: 654 SHSHGNENMHGIFLHILADTLGSVAVVISTILVHFSGWA---GYDPIASCLIAILIFASA 710
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAV 279
PL+ ++ LL +P I+ + ++ L V + V
Sbjct: 711 VPLVTSTAKTLLLALPADIEYN-VRETLAGVSSLRGV 746
>UniRef50_Q5V738 Cluster: Cation efflux system protein; n=1;
Haloarcula marismortui|Rep: Cation efflux system protein
- Haloarcula marismortui (Halobacterium marismortui)
Length = 311
Score = 62.1 bits (144), Expect = 2e-08
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N +G F H+L DA GS+ V+ S V + + DP +LRE
Sbjct: 156 LNERGAFYHLLGDAGGSVAVIVSTAAVAVFDLP---IADPVAAVLIGLLVLASAGNVLRE 212
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI--RCRNLSEY 306
S+ ILL+ P + + ++ L ++GV + + HVWQ+ +A+ + L E
Sbjct: 213 STSILLERSP--VSSEELRDELTTLDGVDQIEDLHVWQVCSQLTVATVRLTDTSTTLEEQ 270
Query: 307 MKIAEKVKEFFHNEGIHSTTIQ 328
+I +V ++ N GI T++
Sbjct: 271 RRIQSRVHDYLTNRGIDHATVE 292
Score = 48.8 bits (111), Expect = 2e-04
Identities = 34/111 (30%), Positives = 58/111 (52%), Gaps = 5/111 (4%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
SG RL + + F +EL G + S+AL++D+ HML D+ A +AF + ++
Sbjct: 21 SGSTRRLALVAVVNFFGFVIELAGGLLFGSVALISDALHMLFDMLAYAMAF-GASYTAER 79
Query: 65 WSKN---TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPK 112
+ ++G R E + A +N V L+ + I E+ +RF+E V NP+
Sbjct: 80 FEGGEAWSYGLHRLEPVAAFLNGVLLLPMVGYIVWESYQRFLE-PVAINPE 129
>UniRef50_Q9ABC7 Cluster: Cation efflux family protein; n=35;
Bacteria|Rep: Cation efflux family protein - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 361
Score = 61.7 bits (143), Expect = 3e-08
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 3/110 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++G FLH+ +DA S VV +AL + T W + +DP W LLR+
Sbjct: 206 LNVRGAFLHMAADAAVSAGVVIAALAMTFTGWMW---LDPVVSLVIVAVIVLGTWGLLRD 262
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
S + L P I ++ L GV VH+ H+W ++ +AH+
Sbjct: 263 SLDLALDATPRGIDTQKVRDWLAARPGVSEVHDLHIWAMSTTETALTAHV 312
Score = 58.0 bits (134), Expect = 3e-07
Identities = 31/84 (36%), Positives = 51/84 (60%), Gaps = 1/84 (1%)
Query: 20 GFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNTFGWARAEVL 78
GF VE G +T+S+AL+AD+ H LSDV L++A+ + ++ + S + T+G + +L
Sbjct: 86 GFVIVEATAGILTHSLALLADAGHNLSDVLGLLLAWGATVLAKRAPSARRTYGLRKGTIL 145
Query: 79 GALVNAVFLVALCFSITVEAVKRF 102
+L NA L+ +I E V+RF
Sbjct: 146 ASLGNAALLLVAVGAIAWEGVRRF 169
>UniRef50_O67851 Cluster: Putative uncharacterized protein; n=1;
Aquifex aeolicus|Rep: Putative uncharacterized protein -
Aquifex aeolicus
Length = 385
Score = 61.3 bits (142), Expect = 4e-08
Identities = 30/77 (38%), Positives = 48/77 (62%)
Query: 24 VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNTFGWARAEVLGALVN 83
++L+ G +T S++L+ D+ H LSD A +IAFLS+K S K + +G + E +GA+V
Sbjct: 20 IKLVGGLLTGSLSLIGDAIHSLSDATASLIAFLSIKFSEIKSERFPYGLYKLENIGAIVI 79
Query: 84 AVFLVALCFSITVEAVK 100
A FL+ + I A+K
Sbjct: 80 AFFLLFTAWEIIQRALK 96
>UniRef50_A1IE74 Cluster: Cobalt-zinc-cadmium resistance protein;
n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep:
Cobalt-zinc-cadmium resistance protein - Candidatus
Desulfococcus oleovorans Hxd3
Length = 331
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/111 (25%), Positives = 58/111 (52%), Gaps = 3/111 (2%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++N +G FLH++ D L S V+ ALV+ + + + +DP LL+
Sbjct: 169 NLNARGAFLHMVGDTLTSAAVLTGALVMRVADMPW---LDPALSLAIVAYIAWNAVLLLK 225
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
E++ +L+ P + ++ ++ ++ V+GV++VH H W + G + + H+
Sbjct: 226 EATHVLMNGTPRGLDLEKVRADMEAVDGVLSVHYLHAWAMGGCSVAMTGHV 276
Score = 48.8 bits (111), Expect = 2e-04
Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KN 68
RLL + + ++ G + S+AL++D+ H L D A+L++A+ + + + S ++
Sbjct: 40 RLLMAMAINLLIPAAQIAGGIVAGSVALISDAVHNLGDFASLVVAYGAHRAGRRGPSLRH 99
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
+FG R E+L A++N+ L I EA+ R
Sbjct: 100 SFGLQRMEILAAVINSALLGGAALFIATEALDR 132
>UniRef50_Q0C865 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 224
Score = 60.9 bits (141), Expect = 5e-08
Identities = 28/73 (38%), Positives = 42/73 (57%), Gaps = 5/73 (6%)
Query: 258 PTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKEFF 317
P H+Q+D L+ + GV+A+HE H+W+L + +AS HI +++ V F
Sbjct: 109 PLHVQLD-----LEKIPGVLAIHELHIWRLNQRKTLASVHIVLPEGADWAGTTRAVNGCF 163
Query: 318 HNEGIHSTTIQPE 330
H GIHS T+QPE
Sbjct: 164 HAHGIHSATLQPE 176
Score = 37.9 bits (84), Expect = 0.40
Identities = 15/28 (53%), Positives = 22/28 (78%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVW 216
+NM GV LH++SDA +L V+ +ALV+W
Sbjct: 72 LNMLGVLLHIISDAANNLGVMAAALVIW 99
>UniRef50_UPI000023F444 Cluster: hypothetical protein FG09632.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG09632.1 - Gibberella zeae PH-1
Length = 547
Score = 60.5 bits (140), Expect = 6e-08
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
R+ + L F V+ GY+T+S+ L++DS HM D AL++ L+ +S KW ++
Sbjct: 224 RIFYFMALNFSFMAVQAFYGYVTDSLGLLSDSIHMFFDCVALMVGLLAAVLS--KWPRSQ 281
Query: 69 --TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+G+ + E L N + L+ L I EA +R E
Sbjct: 282 RFPYGFGKIETLSGFANGILLMLLSVEIAFEAFERLWE 319
Score = 41.9 bits (94), Expect = 0.024
Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 11/140 (7%)
Query: 190 NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRES 249
NM G++LH+L+D LGS+ V+ S ++ + W + + DP PL+ S
Sbjct: 374 NMHGIYLHILADTLGSVSVIVSTILT--SFWGWAGW-DPLASCFIAILIFLSSKPLVYSS 430
Query: 250 SLILLQTVP--THIQVDAIQRRLKNVEGVMAVHEFHVWQ------LAGDRIIASAHIRCR 301
+ LL ++P T + + N GV+ W+ G +++ H+
Sbjct: 431 AKRLLLSIPEDTEYNLRNSLGGILNQRGVVGYSSPKFWRDDHSASPTGGKLLGVVHVVAA 490
Query: 302 NLSEYMKIAEKVKEFFHNEG 321
+ + ++V+E+ EG
Sbjct: 491 RGAPLEDVRDRVREYLLREG 510
>UniRef50_Q8YT81 Cluster: Cation-efflux system membrane protein;
n=1; Nostoc sp. PCC 7120|Rep: Cation-efflux system
membrane protein - Anabaena sp. (strain PCC 7120)
Length = 281
Score = 60.5 bits (140), Expect = 6e-08
Identities = 34/87 (39%), Positives = 52/87 (59%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNTFGWAR 74
L L FF +EL G ++S++L+AD+ H+LSDVAAL +A ++ +S + FG +
Sbjct: 55 LVLLSVFFCIELSAGIWSHSLSLLADAEHILSDVAALGLALIASWLSQSISQRTIFGRYK 114
Query: 75 AEVLGALVNAVFLVALCFSITVEAVKR 101
EVL AL+N + L + I EA+ R
Sbjct: 115 LEVLAALINGISLACIACWIVREALVR 141
>UniRef50_Q2NBG7 Cluster: Cation efflux system protein; n=3;
Proteobacteria|Rep: Cation efflux system protein -
Erythrobacter litoralis (strain HTCC2594)
Length = 317
Score = 60.5 bits (140), Expect = 6e-08
Identities = 29/79 (36%), Positives = 52/79 (65%), Gaps = 1/79 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-NTFGWARAEVLGALVN 83
+++ G ++ S+AL+AD+ H SD A+L +A+ + ++ + K TFG+A+ EV+ AL+N
Sbjct: 36 QIVGGILSGSLALIADALHNFSDAASLGLAWFARRIGRRPADKLMTFGYAQGEVVAALIN 95
Query: 84 AVFLVALCFSITVEAVKRF 102
L+ + F + VEA+ RF
Sbjct: 96 LTTLLIIGFYLIVEAINRF 114
Score = 50.8 bits (116), Expect = 5e-05
Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 6/144 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+NMK FLH +SDAL S+ V+ + +++ L + I LL
Sbjct: 151 INMKAAFLHNVSDALASIGVIVAGVLIILYDLVVADLIITLIIAAYVIWQGAT---LLPR 207
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSE--Y 306
+ +L+ VP ++ D + L+ + GV +H HVW L AH+ + S+ +
Sbjct: 208 TVRLLMGAVPDEVEFDQMVENLRALGGVQDIHHVHVWNLGEHHRALEAHLTLVDYSQTAF 267
Query: 307 MKIAEKVKEFFHNE-GIHSTTIQP 329
+ + + + GI T +P
Sbjct: 268 EGVKRRARAMLEKDFGIAHVTFEP 291
>UniRef50_Q7S953 Cluster: Putative uncharacterized protein
NCU07262.1; n=3; Pezizomycotina|Rep: Putative
uncharacterized protein NCU07262.1 - Neurospora crassa
Length = 604
Score = 60.5 bits (140), Expect = 6e-08
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW---S 66
R+ + + F V+ GY+T+S+ L++DS HM D AL + ++ S KW
Sbjct: 229 RIFYFMSINLSFMAVQAFYGYVTDSLGLLSDSIHMFFDCVALAVGLVAAVAS--KWPPSE 286
Query: 67 KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+ +G+ + E L N VFLV + I EA++R +E
Sbjct: 287 RFPYGFGKIETLSGFANGVFLVLISVEIMFEAIERMME 324
Score = 48.0 bits (109), Expect = 4e-04
Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 4/128 (3%)
Query: 157 HNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVW 216
H+ + + + D + H S + NM G++LHVL+D LGS V+ S ++
Sbjct: 400 HSHSHDHKHDHKHDHGHSHGHSHGGHSHSHDNENMHGIYLHVLADTLGSAAVIVSTILTH 459
Query: 217 LTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGV 276
W DP PL+ S+ LL T+P + + ++ L + G+
Sbjct: 460 FVPWS---GWDPLASFLIAVLILLSSLPLVISSARRLLLTIPPETEYN-LRETLSGISGL 515
Query: 277 MAVHEFHV 284
V + V
Sbjct: 516 RGVAGYSV 523
>UniRef50_Q83MV9 Cluster: Cation efflux protein; n=2; Tropheryma
whipplei|Rep: Cation efflux protein - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 312
Score = 60.1 bits (139), Expect = 9e-08
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 2/96 (2%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK--KWSK 67
RL LCLT GF +EL+ Y++ S+ L +D+ HM D L A ++ ++ K + S
Sbjct: 25 RLFIALCLTVGFTLIELLAVYLSASVTLASDAGHMFIDSLGLFNALIAARLVAKSNRNSH 84
Query: 68 NTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
T+G R EV A V+ + + L F I E++ R +
Sbjct: 85 RTYGLYRVEVFSAGVSILIMFFLAFLIAKESIMRLV 120
Score = 59.7 bits (138), Expect = 1e-07
Identities = 40/141 (28%), Positives = 71/141 (50%), Gaps = 6/141 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N++ ++ VLSDA+ S+ V+ SA+++ LT ID L +E
Sbjct: 157 INLRAAYMEVLSDAIASVSVMLSAILIILTGLTI---IDSIAAIAIVLFICYRAAKLGKE 213
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
ILLQ P IQ ++ L ++GV++V H W L+ ++ IA+A+I ++ K
Sbjct: 214 VIRILLQASPVDIQ--EVESSLLGIDGVISVDHLHAWTLSDEKHIATANILIHKQTDQNK 271
Query: 309 IAEKVKEFFHNE-GIHSTTIQ 328
+ + + + + GI TT+Q
Sbjct: 272 VLVEAERILYEQYGILHTTLQ 292
>UniRef50_Q2J9T2 Cluster: Cation diffusion facilitator family
transporter; n=3; Frankia|Rep: Cation diffusion
facilitator family transporter - Frankia sp. (strain
CcI3)
Length = 405
Score = 60.1 bits (139), Expect = 9e-08
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 2/117 (1%)
Query: 187 GHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
G +N + LH+ DA SL V + +WL Y ++DP LL
Sbjct: 181 GDLNTRAAVLHLAGDAAVSLAVAAAGGAIWLVGGWY--WLDPLVSLVIALLIAVQGARLL 238
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNL 303
+S +LL+ P + V A++ + V+ VH+ HVW L+ + AS H+ +L
Sbjct: 239 ASASRVLLEATPASLDVAAVRADILRDPHVLDVHDLHVWSLSDRLLAASVHLELGHL 295
Score = 51.2 bits (117), Expect = 4e-05
Identities = 30/98 (30%), Positives = 52/98 (53%), Gaps = 1/98 (1%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
+G++ RLL L + G S+ L+AD+ H L+D A +++A ++V +S +
Sbjct: 49 AGQRRRLLLATALNIAIVIGQAAAGLAVGSVGLLADAGHNLTDTAGVVLALVAVALSRRP 108
Query: 65 WS-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
S TFG R VL A NA ++ + + VE+++R
Sbjct: 109 PSASRTFGGVRWPVLAAQANAAAVLVVTALLAVESLRR 146
>UniRef50_A1SIT8 Cluster: Cation diffusion facilitator family
transporter; n=4; Actinomycetales|Rep: Cation diffusion
facilitator family transporter - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 305
Score = 59.7 bits (138), Expect = 1e-07
Identities = 34/102 (33%), Positives = 59/102 (57%), Gaps = 5/102 (4%)
Query: 2 GRYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMS 61
GRY + RL + F VEL+VG ++S+AL++D+ HM +DV AL A ++ +++
Sbjct: 18 GRY---RWRLAVTFAMVATFLVVELVVGLWSHSLALISDAGHMTADVVALGAALVATRIA 74
Query: 62 PKK--WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
+K + T+G RAEV + + + ++ + + VEAV R
Sbjct: 75 TRKDTSGRRTYGSYRAEVFASGLTVLIMLGVAVYVVVEAVGR 116
Score = 54.8 bits (126), Expect = 3e-06
Identities = 33/110 (30%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N+KG + V++DA+GS+ V+ + L+V T + + D L R+
Sbjct: 154 LNVKGAYFEVVADAVGSVGVILAGLLVATTG---QTWWDTGVAVAIGLFVAVRAIVLGRQ 210
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+L Q VP +QVD + L+ + G+ VH+ HVW L +A+AH+
Sbjct: 211 VLAVLGQHVPDGMQVDQVVADLEALPGIEDVHDLHVWTLTSGMNVATAHL 260
>UniRef50_Q9HGQ3 Cluster: Uncharacterized transporter C17D4.03c;
n=1; Schizosaccharomyces pombe|Rep: Uncharacterized
transporter C17D4.03c - Schizosaccharomyces pombe
(Fission yeast)
Length = 732
Score = 59.7 bits (138), Expect = 1e-07
Identities = 29/86 (33%), Positives = 49/86 (56%), Gaps = 1/86 (1%)
Query: 17 LTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNTFGWARA 75
L + FV++I G TNS+ L++D+ HM D A+++ ++ ++ + FG+A+
Sbjct: 356 LNVSYMFVQVIYGLWTNSLGLISDAIHMAFDCIAILVGLVATTLAKMPLNYAYPFGFAKI 415
Query: 76 EVLGALVNAVFLVALCFSITVEAVKR 101
E L N +FLV + FSI EA+ R
Sbjct: 416 EALSGFTNGIFLVLISFSIVGEALYR 441
Score = 40.7 bits (91), Expect = 0.056
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 162 NEETD-EMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSL-IVVGSALVVWLTE 219
NE+ D E + N C + + NM G+FLH+++D +GS+ ++V + L+ W +
Sbjct: 555 NEKCDHESISLQNLDNDHHCHHHHE--NHNMHGIFLHIIADTMGSVGVIVSTILIQWFS- 611
Query: 220 WKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILL 254
W DP PL+++S+ LL
Sbjct: 612 WT---GFDPLASLIIAALIFVSVLPLIKDSAKNLL 643
>UniRef50_Q4Q622 Cluster: Zinc transporter-like protein; n=3;
Leishmania|Rep: Zinc transporter-like protein -
Leishmania major
Length = 457
Score = 59.3 bits (137), Expect = 1e-07
Identities = 39/148 (26%), Positives = 73/148 (49%), Gaps = 14/148 (9%)
Query: 196 LHVLSDALGSLIVVGSALVVWLTEWKY------KHYI----DPXXXXXXXXXXXXXXWPL 245
LH + D + S+ V+ + + ++ + Y +H + DP L
Sbjct: 288 LHAMGDCVQSVGVIFAGIFIYFSNLAYYGNHMYEHSLFNLADPFCSVMFALITLNMTKAL 347
Query: 246 LRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSE 305
L + IL+++ P + A++ L+ ++GV++VH+ HVW L+ + + S H+ N +E
Sbjct: 348 LMDLLSILMESTPASVDYYALETALQQIDGVISVHDLHVWSLSAEYVSLSVHLVADNSAE 407
Query: 306 YMKIAEKV-KEFFHNEGIHSTTIQPEFV 332
++ A+ + KE F GI TTIQ + V
Sbjct: 408 ALQKAQHICKEHF---GIGHTTIQIDSV 432
Score = 53.6 bits (123), Expect = 7e-06
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 3 RYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAF-LSVKMS 61
R S KK LL L F VE G I +S+AL+ D+ H+L+DV + ++ V
Sbjct: 52 RESEKKV-LLGALIFCFVFMIVEFASGVIAHSLALLTDAIHLLTDVGSYALSIGALVAAG 110
Query: 62 PKKWSKNTFGWARAEVLGALVNAVFLVALCFSITVEA 98
+ ++GW RAEV+G L++ + AL I +EA
Sbjct: 111 RTACGRYSYGWHRAEVIGTLISVFSIWALVTWIVIEA 147
>UniRef50_Q5KCD4 Cluster: Cation:cation antiporter, putative; n=2;
Filobasidiella neoformans|Rep: Cation:cation antiporter,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 765
Score = 58.8 bits (136), Expect = 2e-07
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIA-FLSVKMSPKKWSKN 68
R+ L L + V++ G TNS+ L++D+ HML D L + + SV K +
Sbjct: 349 RIFYFLLLNLAYMGVQMGYGVFTNSLGLISDAIHMLFDCLGLGVGLWASVAAMWKPDGRY 408
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
TFG++R E L N FL+ + I EA++R + + + N
Sbjct: 409 TFGYSRVETLSGFANGCFLILISVFIIFEAIQRVVGHQFVGN 450
Score = 53.2 bits (122), Expect = 1e-05
Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 5/145 (3%)
Query: 157 HNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVW 216
HN E D A H + NM+GVFLHVL+D LGS+ V+ S +++
Sbjct: 550 HNDAHAHEDDYDHAHAHGHGHDHDRGHDHAHSHNMRGVFLHVLADTLGSVGVIISTILIR 609
Query: 217 LTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTV--PTHIQVDAIQRRLKNVE 274
T W DP PL+ +S IL V ++ + L +V+
Sbjct: 610 FTGWT---GFDPIASLFIAALIMASVIPLVVDSGRILCLDVGEEKESEIRSALTELSSVD 666
Query: 275 GVMAVHEFHVWQLAGDRIIASAHIR 299
G+ + W ++ S HI+
Sbjct: 667 GLASYAAPRFWPRCEGELVGSIHIQ 691
>UniRef50_A5UNR6 Cluster: Heavy metal cation (Co/Zn/Cd) efflux
system protein, CzcD family; n=1; Methanobrevibacter
smithii ATCC 35061|Rep: Heavy metal cation (Co/Zn/Cd)
efflux system protein, CzcD family - Methanobrevibacter
smithii (strain PS / ATCC 35061 / DSM 861)
Length = 299
Score = 58.8 bits (136), Expect = 2e-07
Identities = 30/97 (30%), Positives = 58/97 (59%), Gaps = 1/97 (1%)
Query: 8 KCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK 67
K LL + L F + ++ G ITNS+A++AD H LSD ++ +A + +S K ++
Sbjct: 14 KGNLLFVFILNITFNVIVILGGLITNSVAILADCLHDLSDTISIGLAGVLEHVSQKNPNE 73
Query: 68 N-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI 103
N T+G+ R +LGA++ ++F++ + + E++ R +
Sbjct: 74 NYTYGYQRFSILGAVITSIFVIIVSVVVVYESISRLL 110
Score = 48.0 bits (109), Expect = 4e-04
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 3/139 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N K + H+L D G + ++ + V L W ++DP L E
Sbjct: 144 INEKVILFHLLGDVFGWIAIL--VISVILMFWNVS-FLDPLLSLIISLWLLYNMGKALHE 200
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMK 308
S +LLQ P ++ VD I+ +++ + + V + H+W L G I + I +++ +
Sbjct: 201 SVCVLLQKSPKNVDVDEIKSQIEGLNHINNVLDIHLWSLDGIDSILTLKINIDDVNNGDE 260
Query: 309 IAEKVKEFFHNEGIHSTTI 327
+ +++ I TT+
Sbjct: 261 VKKEIYTIASKYHIVDTTV 279
>UniRef50_Q2JWZ6 Cluster: Cation transporter, cation diffusion
facilitator (CDF) family; n=7; Cyanobacteria|Rep: Cation
transporter, cation diffusion facilitator (CDF) family -
Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria
bacteriumYellowstone A-Prime)
Length = 304
Score = 58.0 bits (134), Expect = 3e-07
Identities = 33/82 (40%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
Query: 22 FFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKM-SPKKWSKNTFGWARAEVLGA 80
F V+LI+G T S++LVAD+ H ++D A+ I+A L+ + SP+ + +G ++ E +GA
Sbjct: 32 FSVKLILGLATGSLSLVADALHSVTDSASNILALLAARFSSPEPDEDHPYGRSKFEAIGA 91
Query: 81 LVNAVFLVALCFSITVEAVKRF 102
L A FL F I AV RF
Sbjct: 92 LGIAAFLGVASFEILSAAVGRF 113
>UniRef50_Q4Y0W9 Cluster: Zinc transporter, putative; n=3;
Plasmodium (Vinckeia)|Rep: Zinc transporter, putative -
Plasmodium chabaudi
Length = 530
Score = 58.0 bits (134), Expect = 3e-07
Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 13/170 (7%)
Query: 133 HVPPPSNVRH--LTEIVNSN-ADRALGHNST-DNEETDEMVKKAKTQNHKSCKSSSDPGH 188
H+ P N L + +N+N L HN D+ T + K K NH S S
Sbjct: 313 HILPNDNDEEHILFDSLNNNLVGEKLNHNHIHDDHHTHDHSGKHK-HNHSELNSIS---- 367
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+K +LH +SD L ++ V+ ++L++W KY DP +++E
Sbjct: 368 --LKSAYLHAISDLLQNIGVMIASLIIWYNP-KYS-ITDPICSIIFCFIVFSTTLSVIKE 423
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+L++ P I + I+ + + GV+ VH+ HVW L+ + + HI
Sbjct: 424 ILNVLMEGTPVSINLIDIKNDILKIPGVIDVHDLHVWSLSIGKPALACHI 473
Score = 57.6 bits (133), Expect = 5e-07
Identities = 30/103 (29%), Positives = 59/103 (57%), Gaps = 3/103 (2%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
KK + ++C+ F +E+I G ++NS++L+ D+ H+ D+ + + S+ +S + +
Sbjct: 32 KKLIIASIICVI--FMIIEIIAGIVSNSLSLMTDASHLFCDLLSFALNLFSIYVSTFEGN 89
Query: 67 KN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
+ +FG+ RAE++GAL + F+ AL I A R + E +
Sbjct: 90 LDMSFGYHRAEIIGALFSIFFIWALSAYILYSATFRLFQVEQV 132
>UniRef50_Q8SQT3 Cluster: ZINC TRANSPORTER; n=1; Encephalitozoon
cuniculi|Rep: ZINC TRANSPORTER - Encephalitozoon
cuniculi
Length = 334
Score = 58.0 bits (134), Expect = 3e-07
Identities = 28/84 (33%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLG 79
F F+EL + TNS++L+ADS H+L D+ I++ LS+ + K +K TFG+ R E++G
Sbjct: 34 FMFLELWGHWKTNSLSLLADSLHLLVDIFGFIVSLLSLSWAKKPSNKRMTFGYHRIEIIG 93
Query: 80 ALVNAVFLVALCFSITVEAVKRFI 103
++V+ + A + +E+ +++
Sbjct: 94 SMVSIGLIWAAVGYLVIESFHKYL 117
Score = 45.2 bits (102), Expect = 0.003
Identities = 27/128 (21%), Positives = 61/128 (47%), Gaps = 4/128 (3%)
Query: 188 HMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLR 247
++N++ ++HV+ D + S+ V+ + +V + + K +D + R
Sbjct: 158 NLNIRATYVHVVGDLIQSVGVIIAGMVTYF--YPSKAIVDVICTMFFSVLVLISTGFVFR 215
Query: 248 ESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNL--SE 305
+ IL + PT + +D ++ +++VE V + + + W ++ +R S I +L S+
Sbjct: 216 DGVYILAEGAPTDLDIDGMRSDIQDVENVYKIVDLYAWSISMNRSAVSIRILADDLLISD 275
Query: 306 YMKIAEKV 313
Y I +V
Sbjct: 276 YENILLEV 283
>UniRef50_A1RH69 Cluster: Cation diffusion facilitator family
transporter; n=19; Proteobacteria|Rep: Cation diffusion
facilitator family transporter - Shewanella sp. (strain
W3-18-1)
Length = 305
Score = 57.6 bits (133), Expect = 5e-07
Identities = 30/86 (34%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Query: 17 LTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARA 75
L GF +E I G++TNS A++AD+ H L D ++ A+L ++ K ++ T+G+ R
Sbjct: 26 LNVGFTLIEFIGGWLTNSTAIMADAVHDLGDSLSIGSAWLLNRLGRKSANRQFTYGYRRL 85
Query: 76 EVLGALVNAVFLVALCFSITVEAVKR 101
+ GAL+N + L+A + EA+ R
Sbjct: 86 SLFGALINGLVLIAGSVWVLTEAIPR 111
Score = 48.4 bits (110), Expect = 3e-04
Identities = 33/150 (22%), Positives = 63/150 (42%), Gaps = 8/150 (5%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N K + H+L D LG + V+ A+V+ +W +DP L
Sbjct: 147 LNEKVLNWHLLEDVLGWVAVLVVAIVLQFVDWPI---LDPLLSIGFTLFILVNVLRNLST 203
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI-----RCRNL 303
++ + LQ P + IQ L ++ + ++H H+W L G+ + +AH+ +
Sbjct: 204 TARLFLQAAPDSKLQNEIQDTLLKIDELDSIHHLHLWSLDGEHHVLTAHVVTNASKAFTA 263
Query: 304 SEYMKIAEKVKEFFHNEGIHSTTIQPEFVE 333
+ Y I ++ + TTI+ E +
Sbjct: 264 NHYADIKLRIANALEQFDLAHTTIELELTQ 293
>UniRef50_Q55E98 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 614
Score = 57.6 bits (133), Expect = 5e-07
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN--TFGWARAEVL 78
F E+ G S+ LV+D FH L D + IA L++ + + S T+G+ R EVL
Sbjct: 214 FTIYEIFYGAYLESLGLVSDGFHALFDCIGMGIALLAMLVGKRGISNQEYTYGYDRWEVL 273
Query: 79 GALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
G N FL+ + F + +E+++R +E IHN
Sbjct: 274 GTFSNGCFLLFVSFFLFLESIERLLEPPHIHN 305
Score = 37.9 bits (84), Expect = 0.40
Identities = 33/143 (23%), Positives = 62/143 (43%), Gaps = 7/143 (4%)
Query: 175 QNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXX 234
Q K S N+ + H+L D+ SL V+ S+LV + D
Sbjct: 329 QKSNERKQQSSIRSENLLTISHHILVDSCTSLGVILSSLVGQAFGLEIS---DSLISIII 385
Query: 235 XXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNV---EGVMAVHEFHVWQLAGDR 291
P+ ++S ILLQT P ++++ I +K++ EGV+ V + H W +
Sbjct: 386 ACIIVYNALPICIKTSAILLQTTPDQLKIN-INNAIKDILVMEGVIDVTDKHFWSHSPGN 444
Query: 292 IIASAHIRCRNLSEYMKIAEKVK 314
IIA+ ++ + + + + ++
Sbjct: 445 IIATVNLLTKKNCDDFTLTQSIR 467
>UniRef50_A7DRF6 Cluster: Cation diffusion facilitator family
transporter; n=1; Candidatus Nitrosopumilus maritimus
SCM1|Rep: Cation diffusion facilitator family
transporter - Candidatus Nitrosopumilus maritimus SCM1
Length = 450
Score = 57.2 bits (132), Expect = 6e-07
Identities = 32/83 (38%), Positives = 52/83 (62%), Gaps = 5/83 (6%)
Query: 22 FFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK-KWSKNTFGWARAEVLGA 80
F VEL+ G ++NS+AL+ DS H L D ++ L+ +M+ K +++T+G + E LG
Sbjct: 20 FLVELVFGLVSNSLALITDSIHALLDSVVTLVLLLAARMAIKPPDAEHTYGHGKIESLGG 79
Query: 81 LVN--AVFLVALCFSITVEAVKR 101
L+ A+FL+A CF I E++ R
Sbjct: 80 LIGGIAIFLIA-CFFI-YESIHR 100
>UniRef50_Q97LF5 Cluster: C-terminal region cation efflux system
protein CZCD; n=13; Clostridium|Rep: C-terminal region
cation efflux system protein CZCD - Clostridium
acetobutylicum
Length = 403
Score = 56.8 bits (131), Expect = 8e-07
Identities = 30/69 (43%), Positives = 45/69 (65%), Gaps = 2/69 (2%)
Query: 22 FFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-NTFGWARAEVLGA 80
F +EL +G NS+A++AD+FH L+DV+A +I + K+S K K + FG R E L A
Sbjct: 51 FVIELSIGIFINSIAVIADAFHNLADVSASVITLIGFKLSNKPADKEHPFGHGRVEYLSA 110
Query: 81 -LVNAVFLV 88
LV+A+ L+
Sbjct: 111 LLVSAIILL 119
>UniRef50_Q6ML10 Cluster: Cation-efflux system membrane protein;
n=1; Bdellovibrio bacteriovorus|Rep: Cation-efflux
system membrane protein - Bdellovibrio bacteriovorus
Length = 310
Score = 56.8 bits (131), Expect = 8e-07
Identities = 33/93 (35%), Positives = 53/93 (56%), Gaps = 1/93 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKN 68
R+ L L F +ELI G TNS+A+++D+ H D A+++A + K+S ++ K
Sbjct: 29 RMTFALVLNLTFAVIELIGGLWTNSVAILSDALHDFGDAIAMLLAIILEKVSHRQSDGKF 88
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
++G+ R LGA++ + LV I VEAV R
Sbjct: 89 SYGYRRFSTLGAVITGLILVLGSIFILVEAVPR 121
Score = 56.8 bits (131), Expect = 8e-07
Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 6/145 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N K + H++ D LG ++V+ ALV+ + +D LRE
Sbjct: 157 LNEKMLMWHMIEDVLGWVMVLIGALVMKFFDVPQ---LDAGMAIVLAAWILYNVVRNLRE 213
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLS---E 305
+ + L P+HIQV +++ + VE V+ VH H+W L G+ I + H+ + +
Sbjct: 214 ALKVFLMASPSHIQVLDVEKAILEVEHVVGVHHAHLWSLDGENHIFTGHVVVAGSAGPVD 273
Query: 306 YMKIAEKVKEFFHNEGIHSTTIQPE 330
K+ +VK+ + GI TI+ E
Sbjct: 274 IEKVKNQVKKRVRDFGIIEATIETE 298
>UniRef50_A6BDG0 Cluster: Putative uncharacterized protein; n=2;
Clostridiaceae|Rep: Putative uncharacterized protein -
Dorea longicatena DSM 13814
Length = 296
Score = 56.8 bits (131), Expect = 8e-07
Identities = 33/86 (38%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Query: 25 ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKNTFGWARAEVLGALVN 83
+L+ G I +S A+++D+ H LSDV A IAFL VK+S K S++ +G R E + ++V
Sbjct: 32 KLLAGIIGHSGAMISDAVHSLSDVFATFIAFLGVKLSKKSADSEHPYGHDRLECVASMVL 91
Query: 84 AVFLVALCFSITVEAVKRFIEFEVIH 109
A L+A I + VK I + H
Sbjct: 92 AAILLATGIGIGMSGVKTIIAGDYSH 117
>UniRef50_Q3ZWB7 Cluster: Cation efflux family protein; n=2;
Dehalococcoides|Rep: Cation efflux family protein -
Dehalococcoides sp. (strain CBDB1)
Length = 316
Score = 56.4 bits (130), Expect = 1e-06
Identities = 31/90 (34%), Positives = 56/90 (62%), Gaps = 3/90 (3%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS--KNTFGW 72
+ +G E + G +NS+AL++D+ H+L+DV AL +++ ++ M K+ S K TFG+
Sbjct: 25 ILFSGIILLAEFVGGLASNSLALLSDAGHVLTDVLALSLSYFAL-MQAKRPSNFKMTFGY 83
Query: 73 ARAEVLGALVNAVFLVALCFSITVEAVKRF 102
R VL A++N++ L+ + I E+ +RF
Sbjct: 84 HRIGVLVAILNSISLIGIAVFIFYESFQRF 113
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 3/116 (2%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
S ++N+K F H D L S+ V+ SA+VV + + D
Sbjct: 144 SEQKENLNIKSAFWHAAGDTLASVGVIISAVVVI---YSGNYLADIIVSVIIGLIISLGG 200
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ R+ ++L+ P I + + +KN+ GV H H+W ++ + SAH+
Sbjct: 201 INIFRQGLRVILEASPKDINISQLAASVKNIPGVKDFHHIHIWSISPEIHALSAHV 256
>UniRef50_Q6QSW0 Cluster: Cation efflux facilitator; n=1;
Enterococcus faecium|Rep: Cation efflux facilitator -
Enterococcus faecium (Streptococcus faecium)
Length = 307
Score = 56.0 bits (129), Expect = 1e-06
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 10/143 (6%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
SS + G +N LH+L D LG + V+ ++V+ TE + +DP
Sbjct: 150 SSKNEGMLN-----LHMLEDVLGWIGVLVVSIVMNFTE---AYRLDPILSILIALYILYK 201
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDR--IIASAHIR 299
P + ILL P ++ V+ + + N+ V A+ FH+W L G+ +I + I
Sbjct: 202 TVPEFLSTMKILLNGSPENVNVENLASSINNIPAVKALSHFHIWSLDGEENALIVTVLID 261
Query: 300 CRNLSEYMKIAEKVKEFFHNEGI 322
++++ +I E++ E H G+
Sbjct: 262 SSDINKAREIKEEIAELAHTSGV 284
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLG 79
F +E G + NS+++++D+ H L D ++ A+ S K+ + TFG+ R +LG
Sbjct: 35 FSMIEFFFGSLFNSVSIMSDAVHDLGDSISIGFAWFFQGYSEKQQDEQFTFGYNRFSLLG 94
Query: 80 ALVNAVFLVALCFSITVEAVKRFIE 104
AL+ V L+ F + ++ R I+
Sbjct: 95 ALITGVVLIGGSFFMIYRSIPRLID 119
>UniRef50_A0RLZ7 Cluster: Cation efflux family protein; n=1;
Campylobacter fetus subsp. fetus 82-40|Rep: Cation
efflux family protein - Campylobacter fetus subsp. fetus
(strain 82-40)
Length = 314
Score = 56.0 bits (129), Expect = 1e-06
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 10/153 (6%)
Query: 185 DPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTE-WKYKHYIDPXXXXXXXXXXXXXXW 243
D G++N+K F H++SD L S+ ++ ++V+ T W +ID +
Sbjct: 167 DMGNLNIKSSFAHMMSDLLSSVAIILGGIIVYFTNLW----WIDSALALFIAIIIAKWSF 222
Query: 244 PLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR-- 301
L R+S ILL+ P I ++A + + V+ VH+ H+ ++ + +AHI
Sbjct: 223 SLARDSMNILLEASP--IDINAAKNVMLENPLVLDVHDLHISEITHKMYVLTAHIVLNKD 280
Query: 302 NLSEYMKIAEKVKEFFHNE-GIHSTTIQPEFVE 333
N+ ++ +I + N I TIQPE+ E
Sbjct: 281 NIFKFDEIINDLSLSLKNRLEIGHITIQPEWRE 313
Score = 55.6 bits (128), Expect = 2e-06
Identities = 30/95 (31%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSV-KMSPKKWSKNTFGWA 73
L +T + + ITNS+AL++D+ HMLS V AL +++ ++ S + TFG+
Sbjct: 46 LFITVAAMIFQFVYALITNSLALMSDTLHMLSHVIALGLSWFAIWAASSFSSEQKTFGYH 105
Query: 74 RAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
R E + A +N++ + I EA+ + I E I
Sbjct: 106 RLETIAAFINSILIAVFGLFIVYEAIVKLINPEPI 140
>UniRef50_A7RHI7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 293
Score = 56.0 bits (129), Expect = 1e-06
Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 4/119 (3%)
Query: 181 KSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLT-EWKYKHYIDPXXXXXXXXXXX 239
K+ + G++N++ FLH + D + + V+ + L++ + EW+ D
Sbjct: 145 KNDNCEGNINIRAAFLHTIGDIIYAFGVLLAGLIIKIKPEWQKA---DAICSLVGAVIVL 201
Query: 240 XXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ ++R+S IL + VP +++ ++R L + V++ H HVW L R + +AH+
Sbjct: 202 VTTYAVIRDSFNILFEGVPRDVRIAEVKRDLSTLHHVVSFHNVHVWALTSGRNLLTAHL 260
Score = 48.8 bits (111), Expect = 2e-04
Identities = 28/84 (33%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP-KKWSKNTFGWARAEVLG 79
F E+ G I NS+A++ D+ H L D+ +L+ + L+ ++ K S+ T+G+ RAE+LG
Sbjct: 13 FIACEVTGGVIANSLAVMNDALHQLFDLNSLLASLLAAWIAGWKPNSQKTYGYFRAEILG 72
Query: 80 ALVNAVFLVALCFSITVEAVKRFI 103
A + + L L + EA+ R +
Sbjct: 73 ACLVILMLWLLTGVLVYEALLRLL 96
>UniRef50_A5JZM5 Cluster: Cation diffusion facilitator transporter
domain containing protein; n=2; Plasmodium|Rep: Cation
diffusion facilitator transporter domain containing
protein - Plasmodium vivax
Length = 592
Score = 56.0 bits (129), Expect = 1e-06
Identities = 28/103 (27%), Positives = 58/103 (56%), Gaps = 3/103 (2%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
KK + ++C+ F +E++ + NS++L+ D+ H+ D+ + + S+ +S + +
Sbjct: 31 KKLIIASVICII--FMIIEIVAAIVANSLSLMTDASHLFCDLLSFALNLFSIYVSTFEGN 88
Query: 67 KN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVI 108
+ +FG+ RAE++GAL + F+ AL I AV R + + +
Sbjct: 89 VDMSFGYHRAEIIGALFSIFFIWALSAYILYSAVFRLFDVQTV 131
Score = 55.6 bits (128), Expect = 2e-06
Identities = 34/156 (21%), Positives = 69/156 (44%), Gaps = 2/156 (1%)
Query: 176 NHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXX 235
+H+ + +++K +LH +SD L ++ V+ ++L++W KY DP
Sbjct: 415 SHRHSHGQDELNSISLKTAYLHAISDLLQNVGVMIASLIIWYNP-KYS-ITDPICSIIFC 472
Query: 236 XXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIAS 295
+++E +L++ P I + I+ L + GV+ VH+ HVW L+ + +
Sbjct: 473 FIVFSTTISVIKEILNVLMEGTPVSINLIDIKNDLLKIPGVIDVHDLHVWSLSIGKPALA 532
Query: 296 AHIRCRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
HI + + + I TT+Q ++
Sbjct: 533 CHIVAHKNFAHTALNNATLLCHNKYKILHTTVQTDY 568
>UniRef50_Q55JC6 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 839
Score = 56.0 bits (129), Expect = 1e-06
Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIA-FLSVKMSPKKWSKN 68
R+ L L + V++ G TNS+ L++D+ HML D L + + SV K +
Sbjct: 379 RIFYFLLLNLAYMGVQMGYGVFTNSLGLISDAIHMLFDCLGLGVGLWASVAAMWKPDGRY 438
Query: 69 TFGWARAEVLGALVNAVFLVALCFSITVEAVKR 101
TFG++R E L N FL+ + I EA++R
Sbjct: 439 TFGYSRVETLSGFANGCFLILISVFIIFEAIQR 471
Score = 53.2 bits (122), Expect = 1e-05
Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 5/145 (3%)
Query: 157 HNSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVW 216
HN E D A H + NM+GVFLHVL+D LGS+ V+ S +++
Sbjct: 624 HNDAHAHEDDYDHAHAHGHGHDHDRGHDHAHSHNMRGVFLHVLADTLGSVGVIISTILIR 683
Query: 217 LTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTV--PTHIQVDAIQRRLKNVE 274
T W DP PL+ +S IL V ++ + L +V+
Sbjct: 684 FTGWT---GFDPIASLFIAALIMASVIPLVVDSGRILCLDVGEEKESEIRSALTELSSVD 740
Query: 275 GVMAVHEFHVWQLAGDRIIASAHIR 299
G+ + W ++ S HI+
Sbjct: 741 GLASYAAPRFWPRCEGELVGSIHIQ 765
>UniRef50_A6UWS0 Cluster: Cation diffusion facilitator family
transporter; n=1; Methanococcus aeolicus Nankai-3|Rep:
Cation diffusion facilitator family transporter -
Methanococcus aeolicus Nankai-3
Length = 422
Score = 56.0 bits (129), Expect = 1e-06
Identities = 36/100 (36%), Positives = 61/100 (61%), Gaps = 6/100 (6%)
Query: 6 GKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW 65
GKK ++ + LT ++ I+GYI+ S+AL+AD+ H LSDV I ++ +K+S KK
Sbjct: 7 GKKVMVVSAI-LTLFVAILKGIIGYISGSVALIADALHSLSDVLGPIAVYVGLKISQKKP 65
Query: 66 S-KNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+ K +G++RAE L +L F+ + F VE +++ I+
Sbjct: 66 NMKFPYGYSRAETLASL----FVSFIIFLTGVETLRQSID 101
>UniRef50_UPI00015BD034 Cluster: UPI00015BD034 related cluster; n=1;
unknown|Rep: UPI00015BD034 UniRef100 entry - unknown
Length = 286
Score = 55.6 bits (128), Expect = 2e-06
Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
Query: 22 FFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNTFGWARAEVLGA 80
F +E+ GY NS+AL++D+ +M D++ +A ++ +S K + K TFG+ R E+L A
Sbjct: 21 FLLEVYYGYAFNSLALLSDAVYMFMDLSGQALAIFAMYLSKKPPNPKRTFGYYRVEILSA 80
Query: 81 LVNAVFLVALCFSITVEAVKRFIEFEVIH 109
L N + I + A KR + E ++
Sbjct: 81 LFNGITAGFFLIMIFLHAFKRLLHPEYVN 109
Score = 48.8 bits (111), Expect = 2e-04
Identities = 28/115 (24%), Positives = 57/115 (49%), Gaps = 3/115 (2%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N+ G FL VL D L S+ V+ S++++ LT + DP + +L +
Sbjct: 139 LNIAGAFLRVLMDGLSSVGVIASSVLIELTG---NYIFDPIMSILVGLSVIYPIYKVLSK 195
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNL 303
S IL+++ P ++ ++ ++ ++ + + HVW L + I A +R ++L
Sbjct: 196 SIDILMESSPEYVNLEELESFIRKHFPEIMIKSIHVWSLVPSKNIMYARLREQDL 250
>UniRef50_P93574 Cluster: 123.pep; n=4; Magnoliophyta|Rep: 123.pep -
Solanum tuberosum (Potato)
Length = 164
Score = 55.6 bits (128), Expect = 2e-06
Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Query: 7 KKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMS--PKK 64
K ++ L + + VE G+++NS+ L++D+ HML D AAL I + +S P
Sbjct: 17 KSRKIALFLLINTAYMVVEFAAGFMSNSLGLISDACHMLFDCAALAIGLYASYISRLPAN 76
Query: 65 WSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
N +G R EVL NAV LV + I +E+ +R ++
Sbjct: 77 GQFN-YGRGRFEVLSGYTNAVLLVLVGALIVLESFERILD 115
>UniRef50_A5ULB6 Cluster: Cation efflux system protein; n=1;
Methanobrevibacter smithii ATCC 35061|Rep: Cation efflux
system protein - Methanobrevibacter smithii (strain PS /
ATCC 35061 / DSM 861)
Length = 301
Score = 55.6 bits (128), Expect = 2e-06
Identities = 28/85 (32%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Query: 28 VGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKNTFGWARAEVLGALVNAVF 86
+G I+ S AL+++ H LSDVA IIA+L ++ K ++ G RAE + L+ +F
Sbjct: 30 IGIISGSYALISEGAHTLSDVATSIIAYLGFRIGQKPADEEHPLGHGRAEAIAGLIIVLF 89
Query: 87 LVALCFSITVEAVKRFIEFEVIHNP 111
L + + I A+ + + E+I P
Sbjct: 90 LTMVAYEIMTGAINKIVHPELITTP 114
>UniRef50_Q12M16 Cluster: Cation diffusion facilitator family
transporter; n=1; Shewanella denitrificans OS217|Rep:
Cation diffusion facilitator family transporter -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 346
Score = 55.2 bits (127), Expect = 2e-06
Identities = 69/309 (22%), Positives = 121/309 (39%), Gaps = 19/309 (6%)
Query: 6 GKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW 65
GK+ ++L + +T F E+ VG + SMAL+AD +HM + AA I + V +K
Sbjct: 23 GKESKVLIVFFITLVTMFAEIGVGTWSGSMALLADGWHMGTHAAAFAIT-MFVYAYARKH 81
Query: 66 SKN---TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXX 122
S N +FG + LG +AV L+ + + VE++ R E I
Sbjct: 82 SHNSLFSFGTGKVNYLGGFASAVALLIVALLMIVESLHRLWSPESI----AFDEALVVAF 137
Query: 123 XXXXXXXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKA-KTQNHKSCK 181
V + H E + + + H ++ E E A + H
Sbjct: 138 IGLGVNVISVFVLHDEHHHHADE-HHEHHEHHEHHEHHEHHEHHEHHHHADEHHEHHEHH 196
Query: 182 SSSDPGH----MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXX 237
S GH N+ + HVL+D L S++ + + W ++D
Sbjct: 197 EHSHHGHEHKDHNLSAAYFHVLADTLTSVLAILALFAGRYFGWL---WMDALMGIVGAVI 253
Query: 238 XXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAH 297
L++++S +LL V A++ ++ + + V + H+W L+ A
Sbjct: 254 ISKWALGLIKQTSTVLLDKTQAPASVAALKHIIEQ-DPDIKVEDLHLWTLSEGHNAAILS 312
Query: 298 IRCRNLSEY 306
I C + +Y
Sbjct: 313 I-CSHSGQY 320
>UniRef50_Q8IBU1 Cluster: Zinc transporter, putative; n=2;
Plasmodium falciparum|Rep: Zinc transporter, putative -
Plasmodium falciparum (isolate 3D7)
Length = 556
Score = 55.2 bits (127), Expect = 2e-06
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 2/150 (1%)
Query: 182 SSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXX 241
S +D ++++K +LH LSD L ++ V+ ++L +W KY DP
Sbjct: 387 SHNDINNISLKTAYLHALSDLLQNVGVMIASLFIWYDP-KYS-IADPICSIIFCCIVFST 444
Query: 242 XWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR 301
+++E IL++ P I + ++ L + GV+ VH+ HVW L+ + + HI
Sbjct: 445 TISVIKEILNILMEGTPVSINLIDLKNDLLKIPGVLDVHDLHVWSLSIGKPALACHIVAS 504
Query: 302 NLSEYMKIAEKVKEFFHNEGIHSTTIQPEF 331
+ + + + I TT+Q ++
Sbjct: 505 KTYSHSVLNDATLLCQNKYKILHTTVQTDY 534
Score = 53.6 bits (123), Expect = 7e-06
Identities = 27/103 (26%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Query: 3 RYSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSP 62
R + KK + ++C+ F +E++ ++NS++L++D+ H+ D+ + + S+ +S
Sbjct: 31 RKATKKLIIASIICII--FMVIEIVAAIVSNSLSLMSDASHLFCDLLSFALNLFSIYVSS 88
Query: 63 KKWSKN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+ + + +FG+ RAE++GAL + F+ +L I A+ R +
Sbjct: 89 FQGNVDMSFGYHRAEIIGALFSIFFIWSLSAYILYTAIFRLFD 131
>UniRef50_Q0UF07 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 991
Score = 54.8 bits (126), Expect = 3e-06
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNT---FGWARAEV 77
F V+ G+++ S+ L+ DS HML D A L + + MS KW N +G+ + +
Sbjct: 628 FMIVQFFYGFVSGSLGLLTDSIHMLFDCAGLAVGLAAAVMS--KWRPNARFPYGYGKIDT 685
Query: 78 LGALVNAVFLVALCFSITVEAVKRFIE 104
L N VFL+ + I +A +R E
Sbjct: 686 LSGFANGVFLLLVSVEIIFDAFERLWE 712
Score = 42.3 bits (95), Expect = 0.018
Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 190 NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRES 249
NM+G+FLH+L+DALGS+ V+ S L+ W DP PL++ S
Sbjct: 768 NMQGIFLHILADALGSVAVIISTLLTKYYGWS---GWDPIASCIIAILIFLSAIPLVKSS 824
Query: 250 SLILLQTVPTHIQ 262
L+ ++P ++
Sbjct: 825 GARLMLSLPNDLE 837
>UniRef50_Q02XW1 Cluster: Co/Zn/Cd efflux system component; n=3;
Lactococcus lactis|Rep: Co/Zn/Cd efflux system component
- Lactococcus lactis subsp. cremoris (strain SK11)
Length = 305
Score = 54.4 bits (125), Expect = 4e-06
Identities = 29/83 (34%), Positives = 48/83 (57%), Gaps = 1/83 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLG 79
F +E I G I NS A+++D+ H D A+ +A+ K S ++ K+ +FG+ R +LG
Sbjct: 36 FAILEFIFGVIFNSTAILSDAVHDTGDAVAIGLAWFFQKFSKRREDKHFSFGYQRFSLLG 95
Query: 80 ALVNAVFLVALCFSITVEAVKRF 102
A + +V L+ F + EA+ RF
Sbjct: 96 ASLTSVILITGSFIVLFEALPRF 118
Score = 45.2 bits (102), Expect = 0.003
Identities = 30/133 (22%), Positives = 58/133 (43%), Gaps = 3/133 (2%)
Query: 196 LHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQ 255
LH L D LG L V+ ++V+ +W +++DP P + ILL+
Sbjct: 160 LHALEDVLGWLGVLIVSIVLHFVDW---YWLDPLLSILIALFILSKAIPKFWGTLRILLE 216
Query: 256 TVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKE 315
+VP I + L+ + V +V + +W + G++ A HI ++ + V+
Sbjct: 217 SVPEDIDYKKLLIALEKLPEVRSVTQLIIWSIDGEQNAAMIHIVIPENQDFSEAKIAVRT 276
Query: 316 FFHNEGIHSTTIQ 328
+E + + I+
Sbjct: 277 LLESEKVCRSAIE 289
>UniRef50_A4C4Q3 Cluster: Putative CzcD, Co/Zn/Cd efflux system
component protein; n=3; Alteromonadales|Rep: Putative
CzcD, Co/Zn/Cd efflux system component protein -
Pseudoalteromonas tunicata D2
Length = 303
Score = 54.4 bits (125), Expect = 4e-06
Identities = 28/101 (27%), Positives = 54/101 (53%)
Query: 4 YSGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK 63
+ + RLL L +T F +++ Y NS+A++AD+ H+ ++L IA L+ ++ K
Sbjct: 7 HKSSRRRLLIALSITCTFMIIQVFAAYFANSLAVLADAGHLFIHNSSLFIAILASTLAIK 66
Query: 64 KWSKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+ G+ +AE+ G L+N + + + I + +RF E
Sbjct: 67 LATTYNDGYRKAELGGGLINGLLYLIISSYILFKGGERFFE 107
>UniRef50_Q9KDH5 Cluster: Cation efflux system; n=4;
Bacillaceae|Rep: Cation efflux system - Bacillus
halodurans
Length = 300
Score = 54.0 bits (124), Expect = 6e-06
Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Query: 20 GFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSV---KMSPKKWSKNTFGWARAE 76
G ++ IVG I NS AL+AD+ H SDV + ++ + V KM P + + +G +AE
Sbjct: 24 GLAAMKAIVGMIANSKALIADAVHSASDVVSSVVVLIGVRAAKMPPDE--DHPYGHGKAE 81
Query: 77 VLGALVNAVFLVALCFSITVEAVKRFIE 104
+ +++ AV L + F I V A + F E
Sbjct: 82 SVASIIVAVLLFIVGFEIAVSAFQSFFE 109
>UniRef50_A6SZ19 Cluster: Cobalt-zinc-cadmium resistance protein
CzcD; n=33; cellular organisms|Rep: Cobalt-zinc-cadmium
resistance protein CzcD - Janthinobacterium sp. (strain
Marseille) (Minibacterium massiliensis)
Length = 309
Score = 53.6 bits (123), Expect = 7e-06
Identities = 31/97 (31%), Positives = 53/97 (54%), Gaps = 2/97 (2%)
Query: 15 LCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK--KWSKNTFGW 72
L LT E+I GY NSMAL+AD +HM S AL +A ++ ++ + + FG
Sbjct: 31 LLLTTVMMVAEIISGYAFNSMALLADGWHMSSHSVALGLAVMAYVLARRYANDQRFAFGT 90
Query: 73 ARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
+ E+LGA +A+ L+ + + ++++R I +H
Sbjct: 91 WKIEILGAYTSALLLLLVAALMLYQSIERLINPTAVH 127
Score = 33.9 bits (74), Expect = 6.4
Identities = 21/101 (20%), Positives = 44/101 (43%), Gaps = 7/101 (6%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSAL--VVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLL 246
+N++ ++HV++DA S++ + + +W W +DP + L+
Sbjct: 172 LNLRSAYMHVIADAATSVLAIIALFGGKLWGASW-----LDPAMGIVGAALVSVWAYGLI 226
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQL 287
R+S LL V+ I+ + A+ + HVW++
Sbjct: 227 RDSGRFLLDAEMNAPVVEEIREVIAASPIPAAICDLHVWRV 267
>UniRef50_A6LXL8 Cluster: Cation diffusion facilitator family
transporter; n=3; Clostridiales|Rep: Cation diffusion
facilitator family transporter - Clostridium
beijerinckii NCIMB 8052
Length = 298
Score = 53.6 bits (123), Expect = 7e-06
Identities = 26/79 (32%), Positives = 49/79 (62%), Gaps = 1/79 (1%)
Query: 24 VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-NTFGWARAEVLGALV 82
++LIVG T S+++++++ H D+ A IIAF SVK+S K + +G + E + ++
Sbjct: 21 LKLIVGLATGSVSIISEAIHSTMDLLAAIIAFFSVKISDKPADDIHPYGHGKIENVSGVI 80
Query: 83 NAVFLVALCFSITVEAVKR 101
A+ +++ I +EAVK+
Sbjct: 81 EAILILSASIWIIIEAVKK 99
>UniRef50_A1W9S8 Cluster: Cation diffusion facilitator family
transporter; n=31; cellular organisms|Rep: Cation
diffusion facilitator family transporter - Acidovorax
sp. (strain JS42)
Length = 333
Score = 53.2 bits (122), Expect = 1e-05
Identities = 70/317 (22%), Positives = 119/317 (37%), Gaps = 34/317 (10%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNT 69
R+ ++ LT G E++ G + SMALVAD +HM + A++I L+ + + +
Sbjct: 35 RVWLVIALTAGMMVAEILAGKLYGSMALVADGWHMSTHAGAMLITALAYGYARRHAANPR 94
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXXXXXX 129
F + + +G L V L + A + F+ + NP
Sbjct: 95 FSFGTGK-MGDLAGFASAVVLAIVALLIAWESFLR---LTNPVPIRFEQAIA-------- 142
Query: 130 XXXHVPPPSNVRHLTEIVNSNADRAL----GHNSTDNEETDEMVKKAKTQNHKSCKSSSD 185
V + +VN + R L GH+ ++ + +H
Sbjct: 143 ----------VAVIGLVVNLVSARLLHGGHGHHHHGHDHGHDHHHADHDHDHDHDHDHGR 192
Query: 186 PGH-MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWP 244
GH N++ +LHVL+DAL S++ + + LV W + DP W
Sbjct: 193 HGHDNNLRAAYLHVLADALTSVLAIAALLVGRSYGWL---WADPAMGVVGALVIARWSWG 249
Query: 245 LLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDR---IIASAHIRCR 301
L+R++ +LL QV + G + + HVWQ+ II+ A +
Sbjct: 250 LIRDAGGVLLDAPAEGPQVRQEIEDILAATG-DTLKDLHVWQVGPGHFAAIISVASATPQ 308
Query: 302 NLSEYMKIAEKVKEFFH 318
Y + V E H
Sbjct: 309 PAQHYKALLLPVHELSH 325
>UniRef50_Q8ZUM0 Cluster: Cation efflux system protein; n=1;
Pyrobaculum aerophilum|Rep: Cation efflux system protein
- Pyrobaculum aerophilum
Length = 276
Score = 53.2 bits (122), Expect = 1e-05
Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 13/144 (9%)
Query: 190 NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRES 249
N+K +LH L+D+L S+I + SA+ + L ID PL S
Sbjct: 133 NLKAAYLHALADSLTSIIALASAVSIILAGIP---LIDAVLGLGISAYLFSRALPLFESS 189
Query: 250 SLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI---RCRNLSEY 306
L LL P I +A+++ + + VH+ H+W D IA+ HI L+E
Sbjct: 190 LLSLLDASP--INPEALKKEIG-----LHVHDMHIWSPCPDFKIATLHIVVPENYTLTEL 242
Query: 307 MKIAEKVKEFFHNEGIHSTTIQPE 330
+I ++V+ + GI+ TIQ E
Sbjct: 243 EEIRKRVEHTLRSRGINHVTIQFE 266
Score = 39.9 bits (89), Expect = 0.098
Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Query: 8 KCRLLCMLCLTGGFFFVELIVGYI-TNSMALVADSFHMLSDVAALIIAFLSVKMSPKK-W 65
+ RL+ L G V + GY+ +NS+ ++ D H ++D + +A L+ + +
Sbjct: 2 EARLIAAAALAWGATAVSAL-GYVFSNSVVVLGDFLHGVADALGITLAVLAAWLVARDPG 60
Query: 66 SKNTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
T+G+ RAE L NAV ++ + EA RF +
Sbjct: 61 GVFTYGYHRAESLAIFTNAVMILFGSIYVAYEAALRFFK 99
>UniRef50_UPI00015BCCB5 Cluster: UPI00015BCCB5 related cluster;
n=1; unknown|Rep: UPI00015BCCB5 UniRef100 entry -
unknown
Length = 384
Score = 52.8 bits (121), Expect = 1e-05
Identities = 26/76 (34%), Positives = 45/76 (59%)
Query: 24 VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKNTFGWARAEVLGALVN 83
++L VG+++ S+AL A+ H LSD A I F+S+ MS KK K +G + E +GA+
Sbjct: 20 IKLGVGFLSKSVALKAEGIHSLSDSLASFIGFISIYMSEKKHEKFPYGLYKLENIGAMFI 79
Query: 84 AVFLVALCFSITVEAV 99
+ FL + + ++ +
Sbjct: 80 SFFLFFAAYDMFMDVL 95
>UniRef50_Q7MUS7 Cluster: Heavy metal efflux pump, CzcD family; n=1;
Porphyromonas gingivalis|Rep: Heavy metal efflux pump,
CzcD family - Porphyromonas gingivalis (Bacteroides
gingivalis)
Length = 321
Score = 52.8 bits (121), Expect = 1e-05
Identities = 36/145 (24%), Positives = 66/145 (45%), Gaps = 8/145 (5%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N + V LH+L D LG V+ ++V+ +DP + LRE
Sbjct: 167 LNERAVMLHLLEDVLGWAAVLVVSIVMLFVN---APILDPILSLCITAWILYNVYGNLRE 223
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAH-IRC----RNL 303
+ +LLQ VP I ++ ++ + ++ + +VH+ H+W L G+ + + H + C +
Sbjct: 224 TFKVLLQGVPDGIDLEGLKTDILSLPHIRSVHDIHLWTLDGESHVMTIHVVYCPDDFSSP 283
Query: 304 SEYMKIAEKVKEFFHNEGIHSTTIQ 328
+ E V+E GI TI+
Sbjct: 284 QAVFDMKESVREKCSAHGIRHATIE 308
Score = 51.2 bits (117), Expect = 4e-05
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLG 79
F VEL+ G T S+A+++D+ H D +L IA+ K+S K ++ ++G+ R +LG
Sbjct: 50 FAIVELVGGIFTGSVAILSDALHDFGDSISLGIAWRLQKLSEKGRDRSFSYGYKRFSLLG 109
Query: 80 ALVNAVFLVALCFSITVEAVKRF 102
AL+ ++ L+ + + AV+RF
Sbjct: 110 ALLISIILLVGSVFVIIAAVQRF 132
>UniRef50_A7CNS8 Cluster: Cation diffusion facilitator family
transporter; n=1; Opitutaceae bacterium TAV2|Rep: Cation
diffusion facilitator family transporter - Opitutaceae
bacterium TAV2
Length = 294
Score = 52.8 bits (121), Expect = 1e-05
Identities = 26/78 (33%), Positives = 49/78 (62%), Gaps = 1/78 (1%)
Query: 24 VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN-TFGWARAEVLGALV 82
V+++ G I +S AL+AD ++D+ A ++ +S+K+S K ++ +G +AE LGAL
Sbjct: 9 VKIVTGIIGHSYALIADGIESINDIVASVVVLISLKVSSKPPDEDHPYGHGKAEQLGALF 68
Query: 83 NAVFLVALCFSITVEAVK 100
+A+ L+A +I ++ K
Sbjct: 69 SAISLLAAGATIAFQSTK 86
>UniRef50_A5KR43 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 396
Score = 52.8 bits (121), Expect = 1e-05
Identities = 27/89 (30%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Query: 22 FFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-NTFGWARAEVLGA 80
F V+ +G I +S++++AD+F+ LSD + II+F+ VKM+ K + + FG R E + A
Sbjct: 41 FAVKFTIGVIAHSVSVMADAFNNLSDAGSSIISFIGVKMAEKPADRDHPFGHGRIEYIAA 100
Query: 81 LVNAVFLVALCFSITVEAVKRFIEFEVIH 109
LV + ++ + F+ +++ + E+++
Sbjct: 101 LVVSFLILEVGFTFLKDSIGKIRTPEMLN 129
>UniRef50_A3RS25 Cluster: CzcD; n=3; Ralstonia solanacearum|Rep:
CzcD - Ralstonia solanacearum UW551
Length = 439
Score = 52.8 bits (121), Expect = 1e-05
Identities = 33/102 (32%), Positives = 56/102 (54%), Gaps = 2/102 (1%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPK--KWSK 67
R L + LT E++ G+ T SMAL+AD +HM + V AL IA + ++ + + +
Sbjct: 64 RTLYAVLLTAAMMVAEILGGWWTGSMALLADGWHMSTHVLALGIALAAYVIARRLGEDPR 123
Query: 68 NTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
TFG + E+LG+ +A+ L + + VE+V+ + IH
Sbjct: 124 FTFGTWKIEILGSFASALLLGVVGVLVVVESVQHLLAPVDIH 165
Score = 44.0 bits (99), Expect = 0.006
Identities = 29/101 (28%), Positives = 52/101 (51%), Gaps = 8/101 (7%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKY--KHYIDPXXXXXXXXXXXXXXWPLL 246
+N++ +LHV++DA S++ +G+ L+ KY +IDP + LL
Sbjct: 292 LNLRAAYLHVMADAATSVLALGA-----LSTGKYLGLRWIDPMVGIVGALVIGQWAYSLL 346
Query: 247 RESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQL 287
+ + +LL DAIQR L+ GV+ V++ H+W++
Sbjct: 347 KRAGGVLLDRGDDPDLQDAIQRALEAESGVV-VNDLHLWRV 386
>UniRef50_A1ZDC5 Cluster: Heavy metal efflux pump, CzcD family; n=1;
Microscilla marina ATCC 23134|Rep: Heavy metal efflux
pump, CzcD family - Microscilla marina ATCC 23134
Length = 331
Score = 52.8 bits (121), Expect = 1e-05
Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW-SKNTFGWARAEVLG 79
F +ELI G +TNSMA+++D+ H L D A+ A+ + S K + +G+ R L
Sbjct: 61 FTIIELIGGVLTNSMAIMSDAIHDLGDTIAIGSAWFMERYSEKGCDDRYNYGYKRFSPLS 120
Query: 80 ALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
A + +V L+ I +E + R I E ++
Sbjct: 121 AFITSVILIVGSVFIFIETIPRLIHPEAVN 150
Score = 52.4 bits (120), Expect = 2e-05
Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 3/116 (2%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
S + +N K V LH++ DALG + V+ ++V+ + IDP
Sbjct: 174 SGNNDSINQKAVMLHLMEDALGWVAVLVGSIVMLFADVPI---IDPILSLLIAVYILYNA 230
Query: 243 WPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHI 298
+ LR + LQ VP ++ + ++ + V+ +H+ VW + G +I S H+
Sbjct: 231 FKNLRAILNVFLQAVPPKFDLETTKEKILKIPHVIDLHDVRVWSMDGSEMIMSLHL 286
>UniRef50_Q97WH2 Cluster: Probable cation transport protein; n=1;
Sulfolobus solfataricus|Rep: Probable cation transport
protein - Sulfolobus solfataricus
Length = 271
Score = 52.8 bits (121), Expect = 1e-05
Identities = 40/175 (22%), Positives = 79/175 (45%), Gaps = 11/175 (6%)
Query: 160 TDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTE 219
T N+ +V A S + + KG+++H+LSD LG ++ ++++++
Sbjct: 99 TTNDSFTLIVSSALASFLTYFASPKERNDLGKKGLYMHILSDFLGYIMGFIIGILIFISG 158
Query: 220 WKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAV 279
+ +DP PLL+E+ LI ++ + +++D I L + +V
Sbjct: 159 IR---ELDPVGAIILVILNFALSIPLLKEAFLIFME--GSSVKIDHIMEELTKIS--PSV 211
Query: 280 HEFHVWQLAGDRIIASAHIRCR---NLSEYMKIAEKVKEFFHNE-GIHSTTIQPE 330
H HVW + +A+ H++ ++E KI + +F + GI T+Q E
Sbjct: 212 HHLHVWSICDHVKVATLHVKVSPNLTIAEADKIRGSICDFLKEKYGISHVTVQFE 266
Score = 33.5 bits (73), Expect = 8.5
Identities = 17/77 (22%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Query: 26 LIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKW---SKNTFGWARAEVLGALV 82
++ YIT S ++A+ H L D + + +++K + + ++G R EV+ A++
Sbjct: 16 IVAYYITFSPLILAEFSHALIDFLTIAFSIIAIKFIGENEVAEGRFSYGLHRLEVVVAMI 75
Query: 83 NAVFLVALCFSITVEAV 99
N + ++ L ++ +V
Sbjct: 76 NLIIIILLSLAVAYTSV 92
>UniRef50_UPI00005852CD Cluster: PREDICTED: similar to solute
carrier family 30 (zinc transporter), member 6; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
solute carrier family 30 (zinc transporter), member 6 -
Strongylocentrotus purpuratus
Length = 570
Score = 52.4 bits (120), Expect = 2e-05
Identities = 71/316 (22%), Positives = 131/316 (41%), Gaps = 28/316 (8%)
Query: 8 KCRLLCMLCLTGGFFFVELIVG-YITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS 66
+ + + ML L G V +++ TNS+AL A ++ +L DV +L + +++ ++ ++ S
Sbjct: 102 RAKRVLMLGLMGTLCIVTMLLWCQSTNSIALTAFTYIILFDVLSLGVCLITIWVTKQRPS 161
Query: 67 K-NTFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIHNPKXXXXXXXXXXXXX 125
T+G+ R EVL V + ++A+ SI + +K E +I P+
Sbjct: 162 SIYTYGYERFEVLA--VFSTTMLAIFGSIFI--MKESTE-RIIQPPEIHTGRLMLGAILG 216
Query: 126 XXXXXXXHVPPPSNVRHLTEIVNSNADRALGHNSTDNEETDEMVKKAKTQNHKSCKSSSD 185
HL + S ++A H ST ++ + + + C
Sbjct: 217 LFS-------------HLVLLYGSR-NQAFSHVSTASKSS-WLQEHFADICQSFCTVVPG 261
Query: 186 PGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPL 245
H+ + V +L +G ++ + +L + H DP +P+
Sbjct: 262 LDHLLLPRVNPFIL---IGLCSMLSLCVTDFLVDMNNFHMADPLAALCIAMMTVGTMFPM 318
Query: 246 LRESSLILLQTVPTHI--QVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRC-RN 302
S ILLQT P HI Q+D R ++GV+ H W L+ ++ S ++R R+
Sbjct: 319 SVYSGTILLQTTPAHILGQLDKSLREASTLDGVLEFRNEHFWTLSFGQLAGSLNVRVRRD 378
Query: 303 LSEYMKIAEKVKEFFH 318
E M +A + H
Sbjct: 379 ADEQMVLAHVFNKLSH 394
>UniRef50_Q8T0G1 Cluster: LD05335p; n=1; Drosophila
melanogaster|Rep: LD05335p - Drosophila melanogaster
(Fruit fly)
Length = 498
Score = 52.4 bits (120), Expect = 2e-05
Identities = 30/141 (21%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Query: 158 NSTDNEETDEMVKKAKTQNHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWL 217
NS +++ KK + + + + ++N++ +HV+ D + S+ V +A+++ +
Sbjct: 322 NSNEHKIVITNGKKPTLTGTSNMELAHEDKNLNLRAAMIHVIGDLVQSIGVFLAAVLIKV 381
Query: 218 TEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVM 277
Y DP L RES I++ VP ++ + + L ++EGV
Sbjct: 382 CPGA--KYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELGSIEGVR 439
Query: 278 AVHEFHVWQLAGDRIIASAHI 298
++H +VWQ + + H+
Sbjct: 440 SLHHLNVWQQTSQQRVLMVHL 460
Score = 50.8 bits (116), Expect = 5e-05
Identities = 26/103 (25%), Positives = 58/103 (56%), Gaps = 3/103 (2%)
Query: 8 KCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK 67
K +++ + L F +E + GY+ S+A++ D+ H+ SD + +I +++ + + +
Sbjct: 130 KYKIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDE 189
Query: 68 N-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFI--EFEV 107
+FG+ R EV+GAL + + + + + V A++R +FE+
Sbjct: 190 RMSFGYKRFEVIGALASILGIWFVTTLLVVVAIERIFSQDFEL 232
>UniRef50_A7TSV1 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 705
Score = 52.4 bits (120), Expect = 2e-05
Identities = 31/74 (41%), Positives = 41/74 (55%), Gaps = 4/74 (5%)
Query: 183 SSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXX 242
+ D G+ NM+GVFLH+L+D LGS+ VV S L++ LT W DP
Sbjct: 497 AGDHGNENMRGVFLHILADTLGSVGVVISTLLIKLTHWP---IFDPIASILIGSLILLSA 553
Query: 243 WPLLRE-SSLILLQ 255
PL++ SS ILLQ
Sbjct: 554 IPLIKSTSSRILLQ 567
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNT 69
+ L L F FV+L+ + + S+ L++DS HM D +L++ L+ +S + + K
Sbjct: 369 IFSFLLLNTTFMFVQLLYSFRSKSLGLLSDSLHMALDCTSLLLGLLAGILSKRPPNDKFP 428
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
FG E L N + L+ + I +EA+ R F IH
Sbjct: 429 FGMGYLETLTGFTNGILLIGIVSGIFIEAIGRI--FNPIH 466
>UniRef50_A5G751 Cluster: Cation diffusion facilitator family
transporter; n=1; Geobacter uraniumreducens Rf4|Rep:
Cation diffusion facilitator family transporter -
Geobacter uraniumreducens Rf4
Length = 293
Score = 52.0 bits (119), Expect = 2e-05
Identities = 35/143 (24%), Positives = 63/143 (44%), Gaps = 6/143 (4%)
Query: 189 MNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRE 248
+N + V H+L D LG V+ + V+ +K +DP L++
Sbjct: 141 LNARIVTWHLLGDLLGWAAVLSVSSVLL---FKDLPLLDPILSILITSYVLFNVSRNLKK 197
Query: 249 SSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCR---NLSE 305
+ + LQ VP I I+++L ++ V +VH HVW L G+ + + H+ +
Sbjct: 198 TVQLFLQAVPGGIDTGEIEKKLLAIDKVKSVHHTHVWSLDGEHNVLTTHLVVEADATRKD 257
Query: 306 YMKIAEKVKEFFHNEGIHSTTIQ 328
+KI +V+ N TT++
Sbjct: 258 VLKIRNRVRLLLENADFEHTTVE 280
Score = 47.2 bits (107), Expect = 6e-04
Identities = 31/103 (30%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 5 SGKKCRLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKK 64
+G + L LC T +EL G TNS+A+++++ H L D +L +A+ + K+
Sbjct: 12 AGLRLAFLLNLCFT----LLELFGGLWTNSIAIISNAVHDLGDCLSLGLAWYLAGYAEKE 67
Query: 65 WSKN-TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFE 106
+ ++G+ R +LGAL A+ L+ + EAV R + E
Sbjct: 68 SDRRYSYGYRRFSLLGALATALVLMVGSLLVLSEAVPRLLRPE 110
>UniRef50_A1FMN4 Cluster: Cation diffusion facilitator family
transporter; n=2; Proteobacteria|Rep: Cation diffusion
facilitator family transporter - Pseudomonas putida W619
Length = 331
Score = 52.0 bits (119), Expect = 2e-05
Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Query: 10 RLLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSKN- 68
R L ++ LT E+ GY+T SMAL+AD FHM + AL IA + + K + +
Sbjct: 23 RTLWVVMLTVVMMVGEIAAGYVTGSMALLADGFHMATHAGALGIAAAAYAYARKHSASSA 82
Query: 69 -TFGWARAEVLGALVNAVFLVALCFSITVEAVKRFIE 104
+FG + LG +A+ L + I +E+V R +
Sbjct: 83 YSFGTGKVGDLGGFASALILGLVSLGIGIESVLRLFQ 119
Score = 42.7 bits (96), Expect = 0.014
Identities = 24/112 (21%), Positives = 50/112 (44%), Gaps = 5/112 (4%)
Query: 176 NHKSCKSSSDPGHMNMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXX 235
+H + G N++ +LHVL+DA+ S++ + + L W ++DP
Sbjct: 154 SHSHGHHTHSHGDNNLRSAYLHVLADAVTSVMAIVALLAGRYLGWV---WLDPVMGIIGA 210
Query: 236 XXXXXXXWPLLRESSLILLQTVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQL 287
W L+++++ +LL + + R L G + + + HVW++
Sbjct: 211 VVIARWAWLLMKDTAAVLLDKTDNPVAEEI--RELLGQAGDLQITDLHVWKV 260
>UniRef50_Q4QD72 Cluster: Cation transporter, putative; n=4;
Leishmania|Rep: Cation transporter, putative -
Leishmania major
Length = 613
Score = 52.0 bits (119), Expect = 2e-05
Identities = 37/104 (35%), Positives = 59/104 (56%), Gaps = 7/104 (6%)
Query: 5 SGKKCRLLCMLCLTGG----FFFV-ELIVGYITNSMALVADSFHMLSDVAALIIAFLSVK 59
SGK R + L GG FF V +L +G S+ALVAD FH L+D+ A II+++++
Sbjct: 43 SGKCLRQCQIATLAGGATNVFFCVTKLWIGSAGGSVALVADGFHSLTDILADIISYVAIS 102
Query: 60 MSPKKWSKNTF--GWARAEVLGALVNAVFLVALCFSITVEAVKR 101
+S KK + F G R E GA++ A L ++ V+++++
Sbjct: 103 LSRKKLPRCRFPLGIGRLETSGAVIVAAILFFGGVALLVQSLEQ 146
>UniRef50_Q03455 Cluster: Probable zinc transporter MSC2; n=2;
Saccharomyces cerevisiae|Rep: Probable zinc transporter
MSC2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 724
Score = 52.0 bits (119), Expect = 2e-05
Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)
Query: 11 LLCMLCLTGGFFFVELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWS-KNT 69
+ L L F FV+L+ + + S+ L++DS HM D +L++ ++ ++ K S K
Sbjct: 388 IFSFLLLNTAFMFVQLLYSFRSKSLGLLSDSLHMALDCTSLLLGLIAGVLTKKPASDKFP 447
Query: 70 FGWARAEVLGALVNAVFLVALCFSITVEAVKRFIEFEVIH 109
FG L N V L+ + I VEA++R F IH
Sbjct: 448 FGLNYLGTLAGFTNGVLLLGIVCGIFVEAIERI--FNPIH 485
Score = 48.4 bits (110), Expect = 3e-04
Identities = 26/65 (40%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 190 NMKGVFLHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRES 249
NMKG+FLH+L+D LGS+ VV S L++ LT W DP PLL+ +
Sbjct: 524 NMKGIFLHILADTLGSVGVVISTLLIKLTHWP---IFDPIASLLIGSLILLSALPLLKST 580
Query: 250 SLILL 254
S +L
Sbjct: 581 SANIL 585
>UniRef50_Q97NZ2 Cluster: Cation efflux system protein; n=27;
Streptococcus|Rep: Cation efflux system protein -
Streptococcus pneumoniae
Length = 299
Score = 51.6 bits (118), Expect = 3e-05
Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 1/91 (1%)
Query: 21 FFFVELIVGYITNSMALVADSFHMLSDVAAL-IIAFLSVKMSPKKWSKNTFGWARAEVLG 79
+ VE I G + S A++ADS H L D A+ I AFL + ++ ++ T G+ R +LG
Sbjct: 20 YAIVEFIAGGVFGSSAVLADSVHDLGDAIAIGISAFLETISNREEDNQYTLGYKRFSLLG 79
Query: 80 ALVNAVFLVALCFSITVEAVKRFIEFEVIHN 110
ALV AV LV + +E V + + + +++
Sbjct: 80 ALVTAVILVTGSVLVILENVTKILHPQPVND 110
Score = 50.4 bits (115), Expect = 7e-05
Identities = 28/133 (21%), Positives = 58/133 (43%), Gaps = 3/133 (2%)
Query: 196 LHVLSDALGSLIVVGSALVVWLTEWKYKHYIDPXXXXXXXXXXXXXXWPLLRESSLILLQ 255
LH L D LG + V+ A+V+ T+W + +DP P + I L
Sbjct: 144 LHFLEDTLGWVAVILMAIVLRFTDW---YILDPLLSLVISFFILSKALPRFWSTLKIFLD 200
Query: 256 TVPTHIQVDAIQRRLKNVEGVMAVHEFHVWQLAGDRIIASAHIRCRNLSEYMKIAEKVKE 315
VP + + ++ L+ ++ V ++++ ++W + A H+ + + E ++
Sbjct: 201 AVPEGLDIKQVKSGLERLDNVASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRI 260
Query: 316 FFHNEGIHSTTIQ 328
F + G + TI+
Sbjct: 261 FLKDCGFQNITIE 273
>UniRef50_Q57891 Cluster: Uncharacterized transporter MJ0449; n=4;
Euryarchaeota|Rep: Uncharacterized transporter MJ0449 -
Methanococcus jannaschii
Length = 283
Score = 51.6 bits (118), Expect = 3e-05
Identities = 29/86 (33%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Query: 24 VELIVGYITNSMALVADSFHMLSDVAALIIAFLSVKMSPKKWSK-NTFGWARAEVLGALV 82
+++I+GY+ +S++L++D H LSDV II + VK++ K + + +G +R E L +
Sbjct: 21 IKIIIGYVYSSISLISDGIHSLSDVITSIIGIIGVKIASKPPDESHPYGHSRFECLFSFF 80
Query: 83 NAVFLVALCFSITVEAVKRFIEFEVI 108
+ L + I AV+R I EVI
Sbjct: 81 IGLALFFTAYEIGKFAVERIIYGEVI 106
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.322 0.134 0.408
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 334,605,132
Number of Sequences: 1657284
Number of extensions: 11262439
Number of successful extensions: 33116
Number of sequences better than 10.0: 422
Number of HSP's better than 10.0 without gapping: 305
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 32050
Number of HSP's gapped (non-prelim): 787
length of query: 353
length of database: 575,637,011
effective HSP length: 101
effective length of query: 252
effective length of database: 408,251,327
effective search space: 102879334404
effective search space used: 102879334404
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 73 (33.5 bits)
- SilkBase 1999-2023 -