Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001121-TA|BGIBMGA001121-PA|IPR012680|Laminin G,
subdomain 2, IPR001007|von Willebrand factor, type C,
IPR006209|EGF-like, IPR013091|EGF calcium-binding,
IPR008985|Concanavalin A-like lectin/glucanase, IPR009030|Growth
factor, receptor, IPR009041|Proteinase inhibitor, PMP and SGCI,
IPR000152|Aspartic acid and asparagine hydroxylation site,
IPR013032|EGF-like region, IPR000742|EGF-like, type 3,
IPR001881|EGF-like calcium-binding, IPR001791|Laminin G,
IPR003129|Laminin G, Thrombospondin-type, N-terminal, IPR006552|VWC
out, IPR006210|EGF
(654 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 384 e-106
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 383 e-105
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 382 e-105
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 382 e-105
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 382 e-105
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 382 e-105
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 366 e-100
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 366 e-100
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 366 e-100
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 146 3e-34
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 146 3e-34
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 146 3e-34
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 143 2e-33
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 143 2e-33
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 142 3e-33
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 142 3e-33
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 142 3e-33
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 142 3e-33
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 142 3e-33
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 142 3e-33
X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 142 5e-33
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 142 5e-33
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 141 6e-33
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 131 7e-30
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 131 7e-30
M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 131 7e-30
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 131 7e-30
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 131 7e-30
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 131 9e-30
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein. 126 3e-28
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein. 126 3e-28
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein. 126 3e-28
M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromoduli... 124 8e-28
M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromoduli... 124 8e-28
BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein. 124 8e-28
AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor pr... 124 8e-28
BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 123 2e-27
AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module contain... 119 3e-26
AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2 pr... 119 3e-26
AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane hel... 119 3e-26
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 119 4e-26
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 119 4e-26
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 119 4e-26
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 119 4e-26
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 119 4e-26
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 119 4e-26
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 119 4e-26
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 119 4e-26
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 119 4e-26
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 119 4e-26
U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor prot... 118 5e-26
BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein. 118 5e-26
AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein pr... 118 5e-26
AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein. 118 5e-26
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 118 5e-26
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 118 5e-26
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 118 7e-26
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 118 7e-26
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 118 7e-26
X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane ... 118 9e-26
U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein. 118 9e-26
BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module contain... 118 9e-26
BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module contain... 118 9e-26
AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane hel... 118 9e-26
U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein pro... 117 1e-25
BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing fibulin-... 117 1e-25
BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing fibulin-... 117 1e-25
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 117 1e-25
AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing fibulin-... 117 1e-25
AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing fibulin-... 117 1e-25
BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein. 117 2e-25
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 116 2e-25
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 116 2e-25
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 116 2e-25
AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 116 2e-25
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 116 2e-25
BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein. 116 3e-25
AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens ... 116 3e-25
AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens ... 116 3e-25
AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein. 116 3e-25
Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 115 5e-25
Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 115 5e-25
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 115 5e-25
X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 115 5e-25
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 115 5e-25
CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein. 115 5e-25
BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein. 115 5e-25
BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein. 115 5e-25
BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing fibulin-... 115 5e-25
AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein. 115 5e-25
AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein. 115 5e-25
AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing fibulin-... 115 5e-25
AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein. 115 5e-25
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 115 5e-25
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 115 5e-25
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 115 5e-25
AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding prot... 115 5e-25
AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein. 114 8e-25
AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 114 8e-25
AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein. 114 8e-25
DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module contain... 114 1e-24
CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein. 114 1e-24
BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein. 114 1e-24
BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein. 114 1e-24
AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein. 114 1e-24
AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries ... 114 1e-24
AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein. 114 1e-24
AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane hel... 114 1e-24
BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB dom... 113 1e-24
AF525689-1|AAN77133.1| 988|Homo sapiens signal peptide-CUB-EGF-... 113 1e-24
Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA seque... 113 2e-24
AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and... 113 2e-24
AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing ... 113 2e-24
X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein. 112 3e-24
AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein. 112 3e-24
Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein. 111 6e-24
Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein. 111 6e-24
X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein. 111 6e-24
X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein. 111 6e-24
X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein. 111 6e-24
U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein. 111 6e-24
BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein. 111 6e-24
AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein. 111 6e-24
AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens ... 111 6e-24
AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein. 111 6e-24
AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D pre... 111 6e-24
AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellu... 111 6e-24
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 111 7e-24
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 111 7e-24
D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein. 111 7e-24
DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein. 111 7e-24
BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming gro... 111 7e-24
AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming gro... 111 7e-24
AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein. 111 7e-24
AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens ... 111 1e-23
AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA seq... 110 1e-23
AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein. 110 1e-23
AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS... 110 1e-23
AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens ... 110 2e-23
BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein. 107 9e-23
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 107 9e-23
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 107 9e-23
AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein. 106 2e-22
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ... 105 4e-22
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor... 105 4e-22
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor... 105 4e-22
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro... 105 4e-22
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 105 6e-22
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 105 6e-22
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 105 6e-22
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 105 6e-22
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 105 6e-22
AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 105 6e-22
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 105 6e-22
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 104 9e-22
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 104 9e-22
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 104 1e-21
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 104 1e-21
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 104 1e-21
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 104 1e-21
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 104 1e-21
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 104 1e-21
AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 103 2e-21
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 103 2e-21
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 103 2e-21
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 103 3e-21
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 103 3e-21
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 103 3e-21
AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming gro... 103 3e-21
BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein. 101 6e-21
BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein. 101 6e-21
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 99 2e-20
AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming gro... 99 4e-20
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 99 6e-20
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 99 6e-20
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 99 6e-20
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 99 6e-20
AK122706-1|BAC85504.1| 814|Homo sapiens ISOFORM. protein. 98 7e-20
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 96 3e-19
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 96 3e-19
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 96 3e-19
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 96 3e-19
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 96 4e-19
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 96 4e-19
AL021578-2|CAI21077.1| 432|Homo sapiens matrilin 4 protein. 95 5e-19
AL021578-1|CAB46380.1| 622|Homo sapiens matrilin 4 protein. 95 5e-19
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 95 7e-19
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 95 7e-19
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 95 7e-19
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 95 7e-19
Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 95 9e-19
M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 95 9e-19
M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 95 9e-19
M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 95 9e-19
BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 95 9e-19
AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 95 9e-19
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 95 9e-19
Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor prot... 94 1e-18
BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein. 94 1e-18
AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein. 94 1e-18
AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein. 94 1e-18
AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein. 94 1e-18
BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multip... 92 5e-18
AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein. 92 5e-18
AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens ... 92 5e-18
AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein pr... 92 5e-18
AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor... 92 5e-18
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 92 6e-18
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 92 6e-18
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 92 6e-18
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 92 6e-18
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 92 6e-18
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 92 6e-18
BC131821-1|AAI31822.1| 317|Homo sapiens FRAS1 protein protein. 91 1e-17
BC131820-1|AAI31821.1| 1976|Homo sapiens FRAS1 protein protein. 91 1e-17
BC060868-1|AAH60868.1| 685|Homo sapiens BMPER protein protein. 91 1e-17
AY324650-1|AAP89012.1| 685|Homo sapiens crossveinless-2 protein. 91 1e-17
AK096150-1|BAC04712.1| 685|Homo sapiens protein ( Homo sapiens ... 91 1e-17
AJ512501-1|CAD54734.1| 4007|Homo sapiens extracellular matrix pr... 91 1e-17
AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein. 91 1e-17
AC131945-1|AAY41027.1| 475|Homo sapiens unknown protein. 91 1e-17
BC060770-1|AAH60770.2| 757|Homo sapiens SUSD1 protein protein. 90 3e-17
AY358746-1|AAQ89106.1| 747|Homo sapiens GRGP2438 protein. 90 3e-17
AL158824-3|CAI12348.2| 705|Homo sapiens sushi domain containing... 90 3e-17
AL158824-2|CAI12347.2| 747|Homo sapiens sushi domain containing... 90 3e-17
AL138756-2|CAI95300.2| 705|Homo sapiens sushi domain containing... 90 3e-17
AL138756-1|CAI95299.2| 747|Homo sapiens sushi domain containing... 90 3e-17
X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 89 5e-17
M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 89 5e-17
L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein. 88 8e-17
BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precu... 88 8e-17
AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein. 88 8e-17
AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precur... 88 8e-17
AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein. 88 8e-17
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 87 1e-16
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 87 1e-16
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 87 1e-16
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 87 1e-16
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 87 1e-16
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 87 1e-16
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 87 1e-16
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 87 1e-16
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 86 3e-16
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 86 3e-16
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 86 3e-16
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 86 3e-16
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 86 3e-16
BC125092-1|AAI25093.1| 757|Homo sapiens cartilage oligomeric ma... 85 6e-16
BC110847-1|AAI10848.1| 757|Homo sapiens cartilage oligomeric ma... 85 6e-16
AC003107-1|AAB86501.1| 817|Homo sapiens COMP_HUMAN protein. 85 6e-16
L32137-1|AAA57253.1| 757|Homo sapiens matrix protein protein. 85 7e-16
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 85 7e-16
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 85 7e-16
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 85 7e-16
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 85 7e-16
AB086984-1|BAC53888.1| 757|Homo sapiens cartilage oligomeric ma... 85 7e-16
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 85 7e-16
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 85 7e-16
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 84 1e-15
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 84 1e-15
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 84 2e-15
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 84 2e-15
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 84 2e-15
BC113371-1|AAI13372.1| 1036|Homo sapiens cysteine rich transmemb... 83 2e-15
BC111989-1|AAI11990.1| 1036|Homo sapiens cysteine rich transmemb... 83 2e-15
AY358371-1|AAQ88737.1| 1036|Homo sapiens CRIM1 protein. 83 2e-15
AK223216-1|BAD96936.1| 757|Homo sapiens cartilage oligomeric ma... 83 2e-15
AF168681-1|AAG37011.1| 925|Homo sapiens CRIM1 protein protein. 83 2e-15
AF167706-1|AAF34409.1| 1036|Homo sapiens cysteine-rich repeat-co... 83 2e-15
AC007378-1|AAX88862.1| 763|Homo sapiens unknown protein. 83 2e-15
AB209139-1|BAD92376.1| 1058|Homo sapiens cysteine-rich motor neu... 83 2e-15
AB075845-1|BAB85551.1| 565|Homo sapiens KIAA1965 protein protein. 83 2e-15
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 83 3e-15
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 83 4e-15
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 83 4e-15
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 83 4e-15
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 83 4e-15
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 83 4e-15
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 83 4e-15
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 83 4e-15
AY205235-1|AAO47606.1| 673|Homo sapiens URG11 protein. 81 1e-14
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 81 1e-14
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 81 2e-14
AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens ... 80 2e-14
BC064487-1|AAH64487.1| 651|Homo sapiens FRAS1 protein protein. 80 3e-14
BC052281-1|AAH52281.1| 651|Homo sapiens FRAS1 protein protein. 80 3e-14
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 80 3e-14
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 80 3e-14
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 80 3e-14
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 79 4e-14
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 79 4e-14
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 79 4e-14
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 79 4e-14
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 79 4e-14
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 79 4e-14
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 79 4e-14
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 79 5e-14
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 79 5e-14
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 79 5e-14
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 79 5e-14
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 79 5e-14
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 79 5e-14
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 79 5e-14
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 79 5e-14
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 79 5e-14
X84700-1|CAA59173.1| 742|Homo sapiens leucocyte antigen CD97 pr... 78 9e-14
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 78 9e-14
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 78 9e-14
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 78 9e-14
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 78 9e-14
BC050456-1|AAH50456.1| 961|Homo sapiens thrombospondin 4 protein. 78 9e-14
BC026690-1|AAH26690.1| 742|Homo sapiens CD97 molecule protein. 78 9e-14
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 78 9e-14
AY566253-1|AAS66982.1| 961|Homo sapiens thrombospondin 4 protein. 78 9e-14
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 78 9e-14
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 78 9e-14
Z19585-1|CAA79635.1| 961|Homo sapiens thrombospondin-4 protein. 78 1e-13
AC013451-1|AAF87081.1| 969|Homo sapiens LTBP-2 protein. 78 1e-13
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 77 1e-13
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 77 1e-13
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 77 1e-13
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 77 1e-13
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 77 1e-13
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 77 1e-13
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 77 2e-13
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 77 2e-13
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 77 2e-13
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 77 2e-13
AL117551-1|CAB55988.1| 511|Homo sapiens hypothetical protein pr... 77 2e-13
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 77 3e-13
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 77 3e-13
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 77 3e-13
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 77 3e-13
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 77 3e-13
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 77 3e-13
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 76 3e-13
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 76 5e-13
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 76 5e-13
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 76 5e-13
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 76 5e-13
BC131763-1|AAI31764.1| 581|Homo sapiens matrilin 4 protein. 75 1e-12
AL021578-3|CAB39280.1| 581|Homo sapiens matrilin 4 protein. 75 1e-12
AJ007581-1|CAA07569.1| 581|Homo sapiens matrilin-4 protein. 75 1e-12
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 74 2e-12
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 74 2e-12
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 74 2e-12
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 74 2e-12
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 73 2e-12
S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprot... 72 7e-12
L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprot... 72 7e-12
D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprot... 72 7e-12
D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprot... 72 7e-12
D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprot... 72 7e-12
DQ067198-1|AAY46157.1| 873|Homo sapiens very low density lipopr... 72 7e-12
AL450467-4|CAH72455.1| 845|Homo sapiens very low density lipopr... 72 7e-12
AL450467-3|CAH72454.1| 873|Homo sapiens very low density lipopr... 72 7e-12
AB208822-1|BAD92059.1| 555|Homo sapiens Very low-density lipopr... 72 7e-12
AL513325-2|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 71 1e-11
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 71 1e-11
AL136322-3|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 71 1e-11
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 71 1e-11
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 71 1e-11
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 71 1e-11
AL513325-3|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 71 1e-11
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 71 1e-11
AL136322-4|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 71 1e-11
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 71 1e-11
AL450467-2|CAH72453.1| 752|Homo sapiens very low density lipopr... 71 2e-11
AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens ... 71 2e-11
BC002909-1|AAH02909.2| 456|Homo sapiens chordin-like 1 protein. 70 3e-11
AL591489-1|CAI41336.1| 450|Homo sapiens chordin-like 1 protein. 70 3e-11
AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 70 3e-11
AL049176-1|CAI42037.1| 450|Homo sapiens chordin-like 1 protein. 70 3e-11
AK074499-1|BAC11024.1| 636|Homo sapiens protein ( Homo sapiens ... 70 3e-11
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 69 4e-11
L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprot... 69 4e-11
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 69 4e-11
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 69 4e-11
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 69 4e-11
BC050675-1|AAH50675.1| 353|Homo sapiens cysteine-rich with EGF-... 69 5e-11
AY608914-1|AAU25841.1| 458|Homo sapiens ventroptin protein. 69 5e-11
AL591489-2|CAI41337.1| 452|Homo sapiens chordin-like 1 protein. 69 5e-11
AL049176-2|CAI42038.1| 452|Homo sapiens chordin-like 1 protein. 69 5e-11
AB209548-1|BAD92785.1| 437|Homo sapiens chordin-like 1 variant ... 69 5e-11
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 69 7e-11
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 69 7e-11
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 68 9e-11
DQ470680-1|ABF06672.1| 373|Homo sapiens CRELD2-zeta protein. 67 2e-10
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 66 3e-10
DQ470679-1|ABF06671.1| 402|Homo sapiens CRELD2-epsilon protein. 66 4e-10
DQ470678-1|ABF06670.1| 353|Homo sapiens CRELD2-delta protein. 66 4e-10
AY358355-1|AAQ88721.1| 353|Homo sapiens RLPR185 protein. 66 4e-10
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 66 5e-10
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 66 5e-10
BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 66 5e-10
BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 66 5e-10
BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 66 5e-10
AY358360-1|AAQ88726.1| 690|Homo sapiens ETL protein. 66 5e-10
AL596269-1|CAI13205.1| 690|Homo sapiens EGF, latrophilin and se... 66 5e-10
AB032017-1|BAD83584.1| 690|Homo sapiens KPG_003 protein protein. 66 5e-10
BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 65 6e-10
BC110320-1|AAI10321.1| 383|Homo sapiens EGF-like-domain, multip... 65 6e-10
AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 65 6e-10
AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 65 6e-10
AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 65 6e-10
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 65 9e-10
BC077719-1|AAH77719.1| 219|Homo sapiens VWCE protein protein. 65 9e-10
BC052564-1|AAH52564.1| 219|Homo sapiens VWCE protein protein. 65 9e-10
BC042143-1|AAH42143.1| 237|Homo sapiens VWCE protein protein. 65 9e-10
AB209121-1|BAD92358.1| 620|Homo sapiens Mutant p53 binding prot... 65 9e-10
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 64 1e-09
DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin... 64 1e-09
AY358522-1|AAQ88886.1| 451|Homo sapiens chordin Like protein. 64 1e-09
AY279091-1|AAQ19180.1| 308|Homo sapiens chordin-related protein... 64 1e-09
AY279090-1|AAQ19179.1| 429|Homo sapiens chordin-related protein... 64 1e-09
AY163868-1|AAO31809.1| 451|Homo sapiens BNF1 protein. 64 1e-09
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 64 1e-09
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 64 1e-09
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 64 1e-09
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 64 2e-09
BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein. 64 2e-09
BC126440-1|AAI26441.1| 321|Homo sapiens OIT3 protein protein. 64 2e-09
BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 64 2e-09
AY358347-1|AAQ88713.1| 406|Homo sapiens VPPP1921 protein. 64 2e-09
AY358339-1|AAQ88705.1| 545|Homo sapiens PPFL826 protein. 64 2e-09
AY013707-1|AAG40096.2| 545|Homo sapiens LZP protein. 64 2e-09
AK096435-1|BAC04788.1| 545|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 64 2e-09
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 64 2e-09
AB075863-1|BAB85569.1| 418|Homo sapiens KIAA1983 protein protein. 64 2e-09
X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA... 63 3e-09
X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for ... 63 3e-09
AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precur... 63 3e-09
L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein. 63 3e-09
BC038242-1|AAH38242.1| 261|Homo sapiens Similar to RIKEN cDNA 1... 63 3e-09
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 63 3e-09
X78565-1|CAA55309.1| 2201|Homo sapiens human tenascin-C protein. 62 5e-09
X56160-1|CAA39628.1| 2199|Homo sapiens tenascin protein. 62 5e-09
AL162425-1|CAI15110.1| 2201|Homo sapiens tenascin C (hexabrachio... 62 5e-09
M55618-1|AAA88083.1| 2203|Homo sapiens hexabrachion protein. 62 6e-09
BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 62 6e-09
AC020594-1|AAY15036.1| 150|Homo sapiens unknown protein. 62 6e-09
AB210038-1|BAE06120.1| 2233|Homo sapiens TNC variant protein pro... 62 6e-09
X05495-1|CAA29045.1| 575|Homo sapiens thrombomodulin protein. 62 8e-09
M16552-1|AAB59508.1| 575|Homo sapiens THBD protein. 62 8e-09
J02973-1|AAA61175.1| 575|Homo sapiens THBD protein. 62 8e-09
D00210-1|BAA00149.1| 575|Homo sapiens thrombomodulin precursor ... 62 8e-09
BC053357-1|AAH53357.1| 575|Homo sapiens thrombomodulin protein. 62 8e-09
BC035602-1|AAH35602.2| 575|Homo sapiens thrombomodulin protein. 62 8e-09
BC020192-1|AAH20192.1| 258|Homo sapiens FRAS1 protein protein. 62 8e-09
AL049651-2|CAB51954.1| 575|Homo sapiens thrombomodulin protein. 62 8e-09
AF495471-1|AAM03232.1| 575|Homo sapiens thrombomodulin protein. 62 8e-09
AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein... 61 1e-08
AL355483-3|CAI22782.1| 700|Homo sapiens low density lipoprotein... 61 1e-08
AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 61 1e-08
DQ470677-1|ABF06669.1| 325|Homo sapiens CRELD2-gamma protein. 60 2e-08
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 60 2e-08
AK093338-1|BAC04136.1| 355|Homo sapiens protein ( Homo sapiens ... 60 2e-08
BC018786-1|AAH18786.1| 592|Homo sapiens Similar to thrombospond... 60 3e-08
U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 59 6e-08
AB052957-1|BAC15607.1| 803|Homo sapiens soluble form FELE-1 pro... 59 6e-08
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 58 7e-08
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 58 7e-08
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 58 7e-08
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 58 7e-08
DQ470676-1|ABF06668.1| 321|Homo sapiens CRELD2-alpha protein. 58 1e-07
BC002894-1|AAH02894.1| 321|Homo sapiens CRELD2 protein protein. 58 1e-07
Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor... 58 1e-07
U41069-1|AAC17464.1| 537|Homo sapiens collagen alpha2(XI) protein. 58 1e-07
U32169-3|AAC50215.1| 1629|Homo sapiens Pro-a2(XI) protein. 58 1e-07
U32169-2|AAC50213.1| 1650|Homo sapiens Pro-a2(XI) protein. 58 1e-07
U32169-1|AAC50214.1| 1736|Homo sapiens Pro-a2(XI) protein. 58 1e-07
L18987-1|AAA35498.1| 663|Homo sapiens alpha-2 type XI collagen ... 58 1e-07
BX248309-4|CAM26007.1| 262|Homo sapiens collagen, type XI, alph... 58 1e-07
BX248309-3|CAM26006.1| 596|Homo sapiens collagen, type XI, alph... 58 1e-07
BX248309-2|CAM26005.1| 1622|Homo sapiens collagen, type XI, alph... 58 1e-07
BC053886-1|AAH53886.1| 290|Homo sapiens COL11A2 protein protein. 58 1e-07
AL845446-3|CAI95551.1| 1650|Homo sapiens collagen, type XI, alph... 58 1e-07
AL844527-6|CAI41834.1| 1650|Homo sapiens collagen, type XI, alph... 58 1e-07
AL844527-5|CAM25784.1| 290|Homo sapiens collagen, type XI, alph... 58 1e-07
AL844527-4|CAM25783.1| 624|Homo sapiens collagen, type XI, alph... 58 1e-07
AL662824-18|CAM24942.1| 290|Homo sapiens collagen, type XI, alp... 58 1e-07
AL662824-17|CAM24941.1| 624|Homo sapiens collagen, type XI, alp... 58 1e-07
AL662824-16|CAI17611.2| 1650|Homo sapiens collagen, type XI, alp... 58 1e-07
AL645940-5|CAM25430.1| 290|Homo sapiens collagen, type XI, alph... 58 1e-07
AL645940-4|CAM25429.1| 624|Homo sapiens collagen, type XI, alph... 58 1e-07
AL645940-3|CAI18063.2| 1650|Homo sapiens collagen, type XI, alph... 58 1e-07
AL031228-17|CAI95624.1| 269|Homo sapiens collagen type XI alpha... 58 1e-07
AL031228-16|CAA20240.1| 1736|Homo sapiens collagen type XI alpha... 58 1e-07
AL031228-15|CAI95623.1| 1650|Homo sapiens collagen type XI alpha... 58 1e-07
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 58 1e-07
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 58 1e-07
AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein. 58 1e-07
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 58 1e-07
S54426-1|AAB25244.1| 109|Homo sapiens fibrillin protein. 57 2e-07
CR457432-1|CAG33713.1| 357|Homo sapiens NOV protein. 57 2e-07
BC015028-1|AAH15028.1| 357|Homo sapiens nephroblastoma overexpr... 57 2e-07
X96584-1|CAA65403.1| 357|Homo sapiens nov protein. 57 2e-07
X78351-1|CAA55146.1| 357|Homo sapiens novH protein. 57 2e-07
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein. 57 2e-07
>BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 384 bits (944), Expect = e-106
Identities = 185/457 (40%), Positives = 251/457 (54%), Gaps = 26/457 (5%)
Query: 41 YLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQATLYVDCHLL 100
Y E++SSG RDE+R HY+ G PR E P+R+ADG WH+VALSVS + L+VDC+ +
Sbjct: 113 YFELESSGLRDEIRYHYIHNG--KPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRI 170
Query: 101 YRRLIPPPDRNFTQPQLTLWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPGLDSECPT 160
Y R+I PPD N P + LW+GQRN KH LFKG +Q+ +++ P+GY+ QCP L+ CPT
Sbjct: 171 YERVIDPPDTNLP-PGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPT 229
Query: 161 CGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATW--Q 218
C F L + +L + ++ KL AE R+S+LE C C+K+C +G ++ D +W
Sbjct: 230 CSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDG 289
Query: 219 RDCNRCSCVHGEITCRPVECDRAECKN---PVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
C C+C G + CR + C C PV G+CC C +C+ G + G+R
Sbjct: 290 DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRIL 349
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
K C E C G + V CP L C +CC+ C G ++C G C E
Sbjct: 350 TKSCRE--CRGGVL----VKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGE 403
Query: 336 NATCMNLNTKYTCKCNQGF---QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
N+ C N NTK TC+C G+ QGD C+D+DEC H+CH+NT CVN+ G Y
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDEC----AAKMHYCHANTVCVNLPGLYR 459
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C C+ GY R D F+C E DEC H C +A+CTNT ++C C+ GY G+G C
Sbjct: 460 CDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFC 519
Query: 453 E--CTEGSHTCHHSARCVNIDG--GFRCECFTENCEL 485
E C G TC +CV G G CE + C L
Sbjct: 520 EEGCRYGG-TCVAPNKCVCPSGFTGSHCEKDIDECAL 555
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/152 (31%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 200 CQKSCYSNGTVHADGATW---QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPT 256
C C G + +G W + C+ CSC G+I CR CD C+NP CCP
Sbjct: 583 CSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD---CQNPSADL-FCCPE 638
Query: 257 C----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
C QCL LY G+ + C +C C +G + C L CP L C+
Sbjct: 639 CDTRVTSQCLDQNGHKLYRSGDNWT-HSCQQCRCLEGEVDCW----PLTCPNLSCE--YT 691
Query: 311 FSVPGECCKFCPGVDYCNMGH-SCDENATCMN 341
+ GECC C D C + + D TC++
Sbjct: 692 AILEGECCPRCVS-DPCLADNITYDIRKTCLD 722
Score = 60.1 bits (139), Expect = 2e-08
Identities = 24/46 (52%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C Q H + +RSG+ W + CQ C CL GEVDCW
Sbjct: 635 CCPECDTRVTSQCLDQNGHKL-YRSGDNWTHSCQQCRCLEGEVDCW 679
Score = 56.8 bits (131), Expect = 2e-07
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 197 QCDCQ--KSCYS-NG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + C NG ++ G W C +C C+ GE+ C P+ C C+ + GE
Sbjct: 638 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGE 697
Query: 253 CCPTCLRQCLLWGNL 267
CCP C+ L N+
Sbjct: 698 CCPRCVSDPCLADNI 712
>BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein.
Length = 763
Score = 383 bits (942), Expect = e-105
Identities = 185/457 (40%), Positives = 251/457 (54%), Gaps = 26/457 (5%)
Query: 41 YLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQATLYVDCHLL 100
Y E++SSG RDE+R HY+ G PR E P+R+ADG WH+VALSVS + L+VDC+ +
Sbjct: 113 YFELESSGLRDEIRYHYIHNG--KPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRI 170
Query: 101 YRRLIPPPDRNFTQPQLTLWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPGLDSECPT 160
Y R+I PPD N P + LW+GQRN KH LFKG +Q+ +++ P+GY+ QCP L+ CPT
Sbjct: 171 YERVIDPPDTNLP-PGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPT 229
Query: 161 CGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATW--Q 218
C F L + +L + ++ KL AE R+S+LE C C+K+C +G ++ D +W
Sbjct: 230 CSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDG 289
Query: 219 RDCNRCSCVHGEITCRPVECDRAECKN---PVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
C C+C G + CR + C C PV G+CC C +C+ G + G+R
Sbjct: 290 DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRIL 349
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
K C E C G + V CP L C +CC+ C G ++C G C E
Sbjct: 350 TKSCWE--CRGGVL----VKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGE 403
Query: 336 NATCMNLNTKYTCKCNQGF---QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
N+ C N NTK TC+C G+ QGD C+D+DEC H+CH+NT CVN+ G Y
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDEC----AAKMHYCHANTVCVNLPGLYR 459
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C C+ GY R D F+C E DEC H C +A+CTNT ++C C+ GY G+G C
Sbjct: 460 CDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFC 519
Query: 453 E--CTEGSHTCHHSARCVNIDG--GFRCECFTENCEL 485
E C G TC +CV G G CE + C L
Sbjct: 520 EEGCRYGG-TCVAPNKCVCPSGFTGSHCEKDIDECAL 555
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/152 (31%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 200 CQKSCYSNGTVHADGATW---QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPT 256
C C G + +G W + C+ CSC G+I CR CD C+NP CCP
Sbjct: 583 CSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD---CQNPSADL-FCCPE 638
Query: 257 C----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
C QCL LY G+ + C +C C +G + C L CP L C+
Sbjct: 639 CDTRVTSQCLDQNGHKLYRSGDNWT-HSCQQCRCLEGEVDCW----PLTCPNLSCE--YT 691
Query: 311 FSVPGECCKFCPGVDYCNMGH-SCDENATCMN 341
+ GECC C D C + + D TC++
Sbjct: 692 AILEGECCPRCVS-DPCLADNITYDIRKTCLD 722
Score = 60.1 bits (139), Expect = 2e-08
Identities = 24/46 (52%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C Q H + +RSG+ W + CQ C CL GEVDCW
Sbjct: 635 CCPECDTRVTSQCLDQNGHKL-YRSGDNWTHSCQQCRCLEGEVDCW 679
Score = 56.8 bits (131), Expect = 2e-07
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 197 QCDCQ--KSCYS-NG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + C NG ++ G W C +C C+ GE+ C P+ C C+ + GE
Sbjct: 638 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGE 697
Query: 253 CCPTCLRQCLLWGNL 267
CCP C+ L N+
Sbjct: 698 CCPRCVSDPCLADNI 712
>D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein.
Length = 810
Score = 382 bits (941), Expect = e-105
Identities = 184/455 (40%), Positives = 250/455 (54%), Gaps = 26/455 (5%)
Query: 41 YLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQATLYVDCHLL 100
Y E++SSG RDE+R HY+ G PR E P+R+ADG WH+VALSVS + L+VDC+ +
Sbjct: 113 YFELESSGLRDEIRYHYIHNG--KPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRI 170
Query: 101 YRRLIPPPDRNFTQPQLTLWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPGLDSECPT 160
Y R+I PPD N P + LW+GQRN KH LFKG +Q+ +++ P+GY+ QCP L+ CPT
Sbjct: 171 YERVIDPPDTNLP-PGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPT 229
Query: 161 CGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATW--Q 218
C F L + +L + ++ KL AE R+S+LE C C+K+C +G ++ D +W
Sbjct: 230 CSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDG 289
Query: 219 RDCNRCSCVHGEITCRPVECDRAECKN---PVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
C C+C G + CR + C C PV G+CC C +C+ G + G+R
Sbjct: 290 DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRIL 349
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
K C E C G + V CP L C +CC+ C G ++C G C E
Sbjct: 350 TKSCRE--CRGGVL----VKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGE 403
Query: 336 NATCMNLNTKYTCKCNQGF---QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
N+ C N NTK TC+C G+ QGD C+D+DEC H+CH+NT CVN+ G Y
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDEC----AAKMHYCHANTVCVNLPGLYR 459
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C C+ GY R D F+C E DEC H C +A+CTNT ++C C+ GY G+G C
Sbjct: 460 CDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFC 519
Query: 453 E--CTEGSHTCHHSARCVNIDG--GFRCECFTENC 483
E C G TC +CV G G CE + C
Sbjct: 520 EEGCRYGG-TCVAPNKCVCPSGFTGSHCEKDIDEC 553
Score = 123 bits (296), Expect = 2e-27
Identities = 99/336 (29%), Positives = 140/336 (41%), Gaps = 54/336 (16%)
Query: 200 CQKSCYSNGTVHADGAT-WQRDCNRC-SCVHGEIT--CRPVECDRAECKNPVLHPGECCP 255
C+ C G V A+G + C C V +IT C P+ C K+ +L +CC
Sbjct: 331 CRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSE---KDHILPENQCCR 387
Query: 256 TCLRQ--CLLWGNLYEHGERFAPKECAECVCHDGNMQ-------CTRVDPELACPRLPCD 306
C C E+ E A C C G + C +D E A C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDID-ECAAKMHYCH 446
Query: 307 PPQQ-FSVPGEC-CKFCPGV-----------DYCNMG-HSCDENATCMNLNTKYTCKCNQ 352
++PG C PG D C G H+CDENA C N ++C C
Sbjct: 447 ANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 353 GFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVD 411
G+ G+G C+ C+E G +G C + +CV C G+T +C ++D
Sbjct: 507 GYVGNGTICRAF--CEE-GCRYGGTCVAPNKCV---------CPSGFTGS---HCEKDID 551
Query: 412 ECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD------GYTCMHVDECTEGSHTCHHSA 465
EC CH + C N PG Y C CR G+ D G +C+ +DEC +HTC + +
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS 611
Query: 466 RCVNIDGGFRCECFT-ENCELSCSWQGRVVSEGATW 500
C+N+ GGF C C + +C C +G + G W
Sbjct: 612 ACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVW 647
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/152 (31%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 200 CQKSCYSNGTVHADGATW---QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPT 256
C C G + +G W + C+ CSC G+I CR CD C+NP CCP
Sbjct: 630 CSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD---CQNPSADL-FCCPE 685
Query: 257 C----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
C QCL LY G+ + C +C C +G + C L CP L C+
Sbjct: 686 CDTRVTSQCLDQNGHKLYRSGDNWT-HSCQQCRCLEGEVDCW----PLTCPNLSCE--YT 738
Query: 311 FSVPGECCKFCPGVDYCNMGH-SCDENATCMN 341
+ GECC C D C + + D TC++
Sbjct: 739 AILEGECCPRCVS-DPCLADNITYDIRKTCLD 769
Score = 60.1 bits (139), Expect = 2e-08
Identities = 24/46 (52%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C Q H + +RSG+ W + CQ C CL GEVDCW
Sbjct: 682 CCPECDTRVTSQCLDQNGHKL-YRSGDNWTHSCQQCRCLEGEVDCW 726
Score = 56.8 bits (131), Expect = 2e-07
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 197 QCDCQ--KSCYS-NG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + C NG ++ G W C +C C+ GE+ C P+ C C+ + GE
Sbjct: 685 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGE 744
Query: 253 CCPTCLRQCLLWGNL 267
CCP C+ L N+
Sbjct: 745 CCPRCVSDPCLADNI 759
>BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 382 bits (941), Expect = e-105
Identities = 184/455 (40%), Positives = 250/455 (54%), Gaps = 26/455 (5%)
Query: 41 YLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQATLYVDCHLL 100
Y E++SSG RDE+R HY+ G PR E P+R+ADG WH+VALSVS + L+VDC+ +
Sbjct: 113 YFELESSGLRDEIRYHYIHNG--KPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRI 170
Query: 101 YRRLIPPPDRNFTQPQLTLWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPGLDSECPT 160
Y R+I PPD N P + LW+GQRN KH LFKG +Q+ +++ P+GY+ QCP L+ CPT
Sbjct: 171 YERVIDPPDTNLP-PGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPT 229
Query: 161 CGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATW--Q 218
C F L + +L + ++ KL AE R+S+LE C C+K+C +G ++ D +W
Sbjct: 230 CSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDG 289
Query: 219 RDCNRCSCVHGEITCRPVECDRAECKN---PVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
C C+C G + CR + C C PV G+CC C +C+ G + G+R
Sbjct: 290 DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRIL 349
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
K C E C G + V CP L C +CC+ C G ++C G C E
Sbjct: 350 TKSCRE--CRGGVL----VKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGE 403
Query: 336 NATCMNLNTKYTCKCNQGF---QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
N+ C N NTK TC+C G+ QGD C+D+DEC H+CH+NT CVN+ G Y
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDEC----AAKMHYCHANTVCVNLPGLYR 459
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C C+ GY R D F+C E DEC H C +A+CTNT ++C C+ GY G+G C
Sbjct: 460 CDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFC 519
Query: 453 E--CTEGSHTCHHSARCVNIDG--GFRCECFTENC 483
E C G TC +CV G G CE + C
Sbjct: 520 EEGCRYGG-TCVAPNKCVCPSGFTGSHCEKDIDEC 553
Score = 123 bits (296), Expect = 2e-27
Identities = 99/336 (29%), Positives = 140/336 (41%), Gaps = 54/336 (16%)
Query: 200 CQKSCYSNGTVHADGAT-WQRDCNRC-SCVHGEIT--CRPVECDRAECKNPVLHPGECCP 255
C+ C G V A+G + C C V +IT C P+ C K+ +L +CC
Sbjct: 331 CRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSE---KDHILPENQCCR 387
Query: 256 TCLRQ--CLLWGNLYEHGERFAPKECAECVCHDGNMQ-------CTRVDPELACPRLPCD 306
C C E+ E A C C G + C +D E A C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDID-ECAAKMHYCH 446
Query: 307 PPQQ-FSVPGEC-CKFCPGV-----------DYCNMG-HSCDENATCMNLNTKYTCKCNQ 352
++PG C PG D C G H+CDENA C N ++C C
Sbjct: 447 ANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 353 GFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVD 411
G+ G+G C+ C+E G +G C + +CV C G+T +C ++D
Sbjct: 507 GYVGNGTICRAF--CEE-GCRYGGTCVAPNKCV---------CPSGFTGS---HCEKDID 551
Query: 412 ECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD------GYTCMHVDECTEGSHTCHHSA 465
EC CH + C N PG Y C CR G+ D G +C+ +DEC +HTC + +
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS 611
Query: 466 RCVNIDGGFRCECFT-ENCELSCSWQGRVVSEGATW 500
C+N+ GGF C C + +C C +G + G W
Sbjct: 612 ACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVW 647
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/152 (31%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 200 CQKSCYSNGTVHADGATW---QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPT 256
C C G + +G W + C+ CSC G+I CR CD C+NP CCP
Sbjct: 630 CSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD---CQNPSADL-FCCPE 685
Query: 257 C----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
C QCL LY G+ + C +C C +G + C L CP L C+
Sbjct: 686 CDTRVTSQCLDQNGHKLYRSGDNWT-HSCQQCRCLEGEVDCW----PLTCPNLSCE--YT 738
Query: 311 FSVPGECCKFCPGVDYCNMGH-SCDENATCMN 341
+ GECC C D C + + D TC++
Sbjct: 739 AILEGECCPRCVS-DPCLADNITYDIRKTCLD 769
Score = 60.1 bits (139), Expect = 2e-08
Identities = 24/46 (52%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C Q H + +RSG+ W + CQ C CL GEVDCW
Sbjct: 682 CCPECDTRVTSQCLDQNGHKL-YRSGDNWTHSCQQCRCLEGEVDCW 726
Score = 56.8 bits (131), Expect = 2e-07
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 197 QCDCQ--KSCYS-NG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + C NG ++ G W C +C C+ GE+ C P+ C C+ + GE
Sbjct: 685 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGE 744
Query: 253 CCPTCLRQCLLWGNL 267
CCP C+ L N+
Sbjct: 745 CCPRCVSDPCLADNI 759
>BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken)
protein.
Length = 810
Score = 382 bits (941), Expect = e-105
Identities = 184/455 (40%), Positives = 250/455 (54%), Gaps = 26/455 (5%)
Query: 41 YLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQATLYVDCHLL 100
Y E++SSG RDE+R HY+ G PR E P+R+ADG WH+VALSVS + L+VDC+ +
Sbjct: 113 YFELESSGLRDEIRYHYIHNG--KPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRI 170
Query: 101 YRRLIPPPDRNFTQPQLTLWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPGLDSECPT 160
Y R+I PPD N P + LW+GQRN KH LFKG +Q+ +++ P+GY+ QCP L+ CPT
Sbjct: 171 YERVIDPPDTNLP-PGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPT 229
Query: 161 CGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATW--Q 218
C F L + +L + ++ KL AE R+S+LE C C+K+C +G ++ D +W
Sbjct: 230 CSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDG 289
Query: 219 RDCNRCSCVHGEITCRPVECDRAECKN---PVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
C C+C G + CR + C C PV G+CC C +C+ G + G+R
Sbjct: 290 DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRIL 349
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
K C E C G + V CP L C +CC+ C G ++C G C E
Sbjct: 350 TKSCRE--CRGGVL----VKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGE 403
Query: 336 NATCMNLNTKYTCKCNQGF---QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
N+ C N NTK TC+C G+ QGD C+D+DEC H+CH+NT CVN+ G Y
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDEC----AAKMHYCHANTVCVNLPGLYR 459
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C C+ GY R D F+C E DEC H C +A+CTNT ++C C+ GY G+G C
Sbjct: 460 CDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFC 519
Query: 453 E--CTEGSHTCHHSARCVNIDG--GFRCECFTENC 483
E C G TC +CV G G CE + C
Sbjct: 520 EEGCRYGG-TCVAPNKCVCPSGFTGSHCEKDIDEC 553
Score = 123 bits (296), Expect = 2e-27
Identities = 99/336 (29%), Positives = 140/336 (41%), Gaps = 54/336 (16%)
Query: 200 CQKSCYSNGTVHADGAT-WQRDCNRC-SCVHGEIT--CRPVECDRAECKNPVLHPGECCP 255
C+ C G V A+G + C C V +IT C P+ C K+ +L +CC
Sbjct: 331 CRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSE---KDHILPENQCCR 387
Query: 256 TCLRQ--CLLWGNLYEHGERFAPKECAECVCHDGNMQ-------CTRVDPELACPRLPCD 306
C C E+ E A C C G + C +D E A C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDID-ECAAKMHYCH 446
Query: 307 PPQQ-FSVPGEC-CKFCPGV-----------DYCNMG-HSCDENATCMNLNTKYTCKCNQ 352
++PG C PG D C G H+CDENA C N ++C C
Sbjct: 447 ANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 353 GFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVD 411
G+ G+G C+ C+E G +G C + +CV C G+T +C ++D
Sbjct: 507 GYVGNGTICRAF--CEE-GCRYGGTCVAPNKCV---------CPSGFTGS---HCEKDID 551
Query: 412 ECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD------GYTCMHVDECTEGSHTCHHSA 465
EC CH + C N PG Y C CR G+ D G +C+ +DEC +HTC + +
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS 611
Query: 466 RCVNIDGGFRCECFT-ENCELSCSWQGRVVSEGATW 500
C+N+ GGF C C + +C C +G + G W
Sbjct: 612 ACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVW 647
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/152 (31%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 200 CQKSCYSNGTVHADGATW---QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPT 256
C C G + +G W + C+ CSC G+I CR CD C+NP CCP
Sbjct: 630 CSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD---CQNPSADL-FCCPE 685
Query: 257 C----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
C QCL LY G+ + C +C C +G + C L CP L C+
Sbjct: 686 CDTRVTSQCLDQNGHKLYRSGDNWT-HSCQQCRCLEGEVDCW----PLTCPNLSCE--YT 738
Query: 311 FSVPGECCKFCPGVDYCNMGH-SCDENATCMN 341
+ GECC C D C + + D TC++
Sbjct: 739 AILEGECCPRCVS-DPCLADNITYDIRKTCLD 769
Score = 60.1 bits (139), Expect = 2e-08
Identities = 24/46 (52%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C Q H + +RSG+ W + CQ C CL GEVDCW
Sbjct: 682 CCPECDTRVTSQCLDQNGHKL-YRSGDNWTHSCQQCRCLEGEVDCW 726
Score = 56.8 bits (131), Expect = 2e-07
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 197 QCDCQ--KSCYS-NG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + C NG ++ G W C +C C+ GE+ C P+ C C+ + GE
Sbjct: 685 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGE 744
Query: 253 CCPTCLRQCLLWGNL 267
CCP C+ L N+
Sbjct: 745 CCPRCVSDPCLADNI 759
>BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor
protein.
Length = 810
Score = 382 bits (941), Expect = e-105
Identities = 184/455 (40%), Positives = 250/455 (54%), Gaps = 26/455 (5%)
Query: 41 YLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQATLYVDCHLL 100
Y E++SSG RDE+R HY+ G PR E P+R+ADG WH+VALSVS + L+VDC+ +
Sbjct: 113 YFELESSGLRDEIRYHYIHNG--KPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRI 170
Query: 101 YRRLIPPPDRNFTQPQLTLWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPGLDSECPT 160
Y R+I PPD N P + LW+GQRN KH LFKG +Q+ +++ P+GY+ QCP L+ CPT
Sbjct: 171 YERVIDPPDTNLP-PGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPT 229
Query: 161 CGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATW--Q 218
C F L + +L + ++ KL AE R+S+LE C C+K+C +G ++ D +W
Sbjct: 230 CSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDG 289
Query: 219 RDCNRCSCVHGEITCRPVECDRAECKN---PVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
C C+C G + CR + C C PV G+CC C +C+ G + G+R
Sbjct: 290 DHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRIL 349
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
K C E C G + V CP L C +CC+ C G ++C G C E
Sbjct: 350 TKSCRE--CRGGVL----VKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGE 403
Query: 336 NATCMNLNTKYTCKCNQGF---QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
N+ C N NTK TC+C G+ QGD C+D+DEC H+CH+NT CVN+ G Y
Sbjct: 404 NSECKNWNTKATCECKSGYISVQGDSAYCEDIDEC----AAKMHYCHANTVCVNLPGLYR 459
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C C+ GY R D F+C E DEC H C +A+CTNT ++C C+ GY G+G C
Sbjct: 460 CDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFC 519
Query: 453 E--CTEGSHTCHHSARCVNIDG--GFRCECFTENC 483
E C G TC +CV G G CE + C
Sbjct: 520 EEGCRYGG-TCVAPNKCVCPSGFTGSHCEKDIDEC 553
Score = 123 bits (296), Expect = 2e-27
Identities = 99/336 (29%), Positives = 140/336 (41%), Gaps = 54/336 (16%)
Query: 200 CQKSCYSNGTVHADGAT-WQRDCNRC-SCVHGEIT--CRPVECDRAECKNPVLHPGECCP 255
C+ C G V A+G + C C V +IT C P+ C K+ +L +CC
Sbjct: 331 CRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSE---KDHILPENQCCR 387
Query: 256 TCLRQ--CLLWGNLYEHGERFAPKECAECVCHDGNMQ-------CTRVDPELACPRLPCD 306
C C E+ E A C C G + C +D E A C
Sbjct: 388 VCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDID-ECAAKMHYCH 446
Query: 307 PPQQ-FSVPGEC-CKFCPGV-----------DYCNMG-HSCDENATCMNLNTKYTCKCNQ 352
++PG C PG D C G H+CDENA C N ++C C
Sbjct: 447 ANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKP 506
Query: 353 GFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVD 411
G+ G+G C+ C+E G +G C + +CV C G+T +C ++D
Sbjct: 507 GYVGNGTICRAF--CEE-GCRYGGTCVAPNKCV---------CPSGFTGS---HCEKDID 551
Query: 412 ECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD------GYTCMHVDECTEGSHTCHHSA 465
EC CH + C N PG Y C CR G+ D G +C+ +DEC +HTC + +
Sbjct: 552 ECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDS 611
Query: 466 RCVNIDGGFRCECFT-ENCELSCSWQGRVVSEGATW 500
C+N+ GGF C C + +C C +G + G W
Sbjct: 612 ACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVW 647
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/152 (31%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 200 CQKSCYSNGTVHADGATW---QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPT 256
C C G + +G W + C+ CSC G+I CR CD C+NP CCP
Sbjct: 630 CSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD---CQNPSADL-FCCPE 685
Query: 257 C----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
C QCL LY G+ + C +C C +G + C L CP L C+
Sbjct: 686 CDTRVTSQCLDQNGHKLYRSGDNWT-HSCQQCRCLEGEVDCW----PLTCPNLSCE--YT 738
Query: 311 FSVPGECCKFCPGVDYCNMGH-SCDENATCMN 341
+ GECC C D C + + D TC++
Sbjct: 739 AILEGECCPRCVS-DPCLADNITYDIRKTCLD 769
Score = 60.1 bits (139), Expect = 2e-08
Identities = 24/46 (52%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C Q H + +RSG+ W + CQ C CL GEVDCW
Sbjct: 682 CCPECDTRVTSQCLDQNGHKL-YRSGDNWTHSCQQCRCLEGEVDCW 726
Score = 56.8 bits (131), Expect = 2e-07
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 197 QCDCQ--KSCYS-NG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + C NG ++ G W C +C C+ GE+ C P+ C C+ + GE
Sbjct: 685 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGE 744
Query: 253 CCPTCLRQCLLWGNL 267
CCP C+ L N+
Sbjct: 745 CCPRCVSDPCLADNI 759
>D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein.
Length = 815
Score = 366 bits (901), Expect = e-100
Identities = 174/455 (38%), Positives = 246/455 (54%), Gaps = 18/455 (3%)
Query: 40 RYLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQATLYVDCHL 99
RYLE++SSG R+EVRLHY +G P E FP+ LAD WH+++L++S + L++DC+
Sbjct: 111 RYLELESSGHRNEVRLHY-RSGSHRPHTEVFPYILADDKWHKLSLAISASHLILHIDCNK 169
Query: 100 LYRRLIPPPDRNFTQPQLTLWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPGLDSECP 159
+Y R++ P + T W+GQRNN H FKG +Q+V+L+ P G++AQCP L+ CP
Sbjct: 170 IYERVVEKPSTDLPLGT-TFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCP 228
Query: 160 TCGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQR 219
TC F L + EL + S KL AE R++RL+QC C+++C GT + + +W
Sbjct: 229 TCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWID 288
Query: 220 DCNRCSCVHGEITCRPVECDRAEC--KNPVLH-PGECCPTCLRQCLLWGNLYEHGER-FA 275
C C+C++G I C + C +C K+ + + G+CC C C G Y GER
Sbjct: 289 GCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNTV 348
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
CV ++ Q ++ CP L C Q ++ CCK C G D+C+ H+C E
Sbjct: 349 YSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCME 408
Query: 336 NATCMNLNTKYTCKCNQGFQG---DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
N+ C NLN + C C GF+ D C+D+DEC E H+C NT CVN G ++
Sbjct: 409 NSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEG----RHYCRENTMCVNTPGSFM 464
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV- 451
C C GY R D ++C E DEC N H C +A+C NT G + C C+ GY G+G TC
Sbjct: 465 CICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFC 524
Query: 452 -DECTEGSHTCHHSARCVNIDG--GFRCECFTENC 483
D C G C + C G G CE + C
Sbjct: 525 KDGCRNGG-ACIAANVCACPQGFTGPSCETDIDEC 558
Score = 120 bits (288), Expect = 2e-26
Identities = 65/189 (34%), Positives = 88/189 (46%), Gaps = 24/189 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C D C H+CDENA C N + C C G+ G+G TC+ C++ C
Sbjct: 479 CTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAF--CKDG-------CR 529
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C+ VC C G+T +C ++DEC C + A C N PG Y C CR
Sbjct: 530 NGGACI---AANVCACPQGFTGP---SCETDIDECSDGFVQCDSRANCINLPGWYHCECR 583
Query: 439 DGYEGDGY------TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC-FTENCELSCSWQG 491
DGY +G +C +DEC G H+C + C N+DGG+ C C +NC C G
Sbjct: 584 DGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDG 643
Query: 492 RVVSEGATW 500
+V G W
Sbjct: 644 KVKHNGQIW 652
Score = 63.7 bits (148), Expect = 2e-09
Identities = 44/134 (32%), Positives = 62/134 (46%), Gaps = 24/134 (17%)
Query: 199 DCQKSCYSNGTVHADGATW--QRD-CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCP 255
+C C +G V +G W + D C+ CSC +G + CR + CD C+NP + CCP
Sbjct: 634 NCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD---CENPTVDL-FCCP 689
Query: 256 TC----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C QCL LY G+ + + C +C C G + C L CP + C
Sbjct: 690 ECDPRLSSQCLHQNGETLYNSGDTWV-QNCQQCRCLQGEVDCW----PLPCPDVEC---- 740
Query: 310 QFSV--PGECCKFC 321
+FS+ ECC C
Sbjct: 741 EFSILPENECCPRC 754
Score = 62.9 bits (146), Expect = 3e-09
Identities = 39/122 (31%), Positives = 60/122 (49%), Gaps = 22/122 (18%)
Query: 197 QCDCQKS--C-YSNG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + S C + NG T++ G TW ++C +C C+ GE+ C P+ C EC+ +L E
Sbjct: 690 ECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDVECEFSILPENE 749
Query: 253 CCPTCL--------------RQCLLWGNLYEH-GERFAP--KECAECVCHDGNMQCTRVD 295
CCP C+ + CL N+ G + EC C C +G++ C VD
Sbjct: 750 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHI-CCSVD 808
Query: 296 PE 297
P+
Sbjct: 809 PQ 810
Score = 57.6 bits (133), Expect = 1e-07
Identities = 23/46 (50%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C HQ + SG+ W+ CQ C CL GEVDCW
Sbjct: 687 CCPECDPRLSSQCLHQN-GETLYNSGDTWVQNCQQCRCLQGEVDCW 731
>D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2
protein.
Length = 816
Score = 366 bits (901), Expect = e-100
Identities = 174/455 (38%), Positives = 246/455 (54%), Gaps = 18/455 (3%)
Query: 40 RYLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQATLYVDCHL 99
RYLE++SSG R+EVRLHY +G P E FP+ LAD WH+++L++S + L++DC+
Sbjct: 112 RYLELESSGHRNEVRLHY-RSGSHRPHTEVFPYILADDKWHKLSLAISASHLILHIDCNK 170
Query: 100 LYRRLIPPPDRNFTQPQLTLWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPGLDSECP 159
+Y R++ P + T W+GQRNN H FKG +Q+V+L+ P G++AQCP L+ CP
Sbjct: 171 IYERVVEKPSTDLPLGT-TFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCP 229
Query: 160 TCGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQR 219
TC F L + EL + S KL AE R++RL+QC C+++C GT + + +W
Sbjct: 230 TCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWID 289
Query: 220 DCNRCSCVHGEITCRPVECDRAEC--KNPVLH-PGECCPTCLRQCLLWGNLYEHGER-FA 275
C C+C++G I C + C +C K+ + + G+CC C C G Y GER
Sbjct: 290 GCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNTV 349
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
CV ++ Q ++ CP L C Q ++ CCK C G D+C+ H+C E
Sbjct: 350 YSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCME 409
Query: 336 NATCMNLNTKYTCKCNQGFQG---DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
N+ C NLN + C C GF+ D C+D+DEC E H+C NT CVN G ++
Sbjct: 410 NSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEG----RHYCRENTMCVNTPGSFM 465
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV- 451
C C GY R D ++C E DEC N H C +A+C NT G + C C+ GY G+G TC
Sbjct: 466 CICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFC 525
Query: 452 -DECTEGSHTCHHSARCVNIDG--GFRCECFTENC 483
D C G C + C G G CE + C
Sbjct: 526 KDGCRNGG-ACIAANVCACPQGFTGPSCETDIDEC 559
Score = 120 bits (288), Expect = 2e-26
Identities = 65/189 (34%), Positives = 88/189 (46%), Gaps = 24/189 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C D C H+CDENA C N + C C G+ G+G TC+ C++ C
Sbjct: 480 CTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAF--CKDG-------CR 530
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C+ VC C G+T +C ++DEC C + A C N PG Y C CR
Sbjct: 531 NGGACI---AANVCACPQGFTGP---SCETDIDECSDGFVQCDSRANCINLPGWYHCECR 584
Query: 439 DGYEGDGY------TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC-FTENCELSCSWQG 491
DGY +G +C +DEC G H+C + C N+DGG+ C C +NC C G
Sbjct: 585 DGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDG 644
Query: 492 RVVSEGATW 500
+V G W
Sbjct: 645 KVKHNGQIW 653
Score = 63.7 bits (148), Expect = 2e-09
Identities = 44/134 (32%), Positives = 62/134 (46%), Gaps = 24/134 (17%)
Query: 199 DCQKSCYSNGTVHADGATW--QRD-CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCP 255
+C C +G V +G W + D C+ CSC +G + CR + CD C+NP + CCP
Sbjct: 635 NCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD---CENPTVDL-FCCP 690
Query: 256 TC----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C QCL LY G+ + + C +C C G + C L CP + C
Sbjct: 691 ECDPRLSSQCLHQNGETLYNSGDTWV-QNCQQCRCLQGEVDCW----PLPCPDVEC---- 741
Query: 310 QFSV--PGECCKFC 321
+FS+ ECC C
Sbjct: 742 EFSILPENECCPRC 755
Score = 62.9 bits (146), Expect = 3e-09
Identities = 39/122 (31%), Positives = 60/122 (49%), Gaps = 22/122 (18%)
Query: 197 QCDCQKS--C-YSNG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + S C + NG T++ G TW ++C +C C+ GE+ C P+ C EC+ +L E
Sbjct: 691 ECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDVECEFSILPENE 750
Query: 253 CCPTCL--------------RQCLLWGNLYEH-GERFAP--KECAECVCHDGNMQCTRVD 295
CCP C+ + CL N+ G + EC C C +G++ C VD
Sbjct: 751 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHI-CCSVD 809
Query: 296 PE 297
P+
Sbjct: 810 PQ 811
Score = 57.6 bits (133), Expect = 1e-07
Identities = 23/46 (50%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C HQ + SG+ W+ CQ C CL GEVDCW
Sbjct: 688 CCPECDPRLSSQCLHQN-GETLYNSGDTWVQNCQQCRCLQGEVDCW 732
>BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein.
Length = 816
Score = 366 bits (901), Expect = e-100
Identities = 174/455 (38%), Positives = 246/455 (54%), Gaps = 18/455 (3%)
Query: 40 RYLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQATLYVDCHL 99
RYLE++SSG R+EVRLHY +G P E FP+ LAD WH+++L++S + L++DC+
Sbjct: 112 RYLELESSGHRNEVRLHY-RSGSHRPHTEVFPYILADDKWHKLSLAISASHLILHIDCNK 170
Query: 100 LYRRLIPPPDRNFTQPQLTLWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPGLDSECP 159
+Y R++ P + T W+GQRNN H FKG +Q+V+L+ P G++AQCP L+ CP
Sbjct: 171 IYERVVEKPSTDLPLGT-TFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCP 229
Query: 160 TCGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQR 219
TC F L + EL + S KL AE R++RL+QC C+++C GT + + +W
Sbjct: 230 TCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWID 289
Query: 220 DCNRCSCVHGEITCRPVECDRAEC--KNPVLH-PGECCPTCLRQCLLWGNLYEHGER-FA 275
C C+C++G I C + C +C K+ + + G+CC C C G Y GER
Sbjct: 290 GCKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNTV 349
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
CV ++ Q ++ CP L C Q ++ CCK C G D+C+ H+C E
Sbjct: 350 YSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCME 409
Query: 336 NATCMNLNTKYTCKCNQGFQG---DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
N+ C NLN + C C GF+ D C+D+DEC E H+C NT CVN G ++
Sbjct: 410 NSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEG----RHYCRENTMCVNTPGSFM 465
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV- 451
C C GY R D ++C E DEC N H C +A+C NT G + C C+ GY G+G TC
Sbjct: 466 CICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFC 525
Query: 452 -DECTEGSHTCHHSARCVNIDG--GFRCECFTENC 483
D C G C + C G G CE + C
Sbjct: 526 KDGCRNGG-ACIAANVCACPQGFTGPSCETDIDEC 559
Score = 120 bits (288), Expect = 2e-26
Identities = 65/189 (34%), Positives = 88/189 (46%), Gaps = 24/189 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C D C H+CDENA C N + C C G+ G+G TC+ C++ C
Sbjct: 480 CTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAF--CKDG-------CR 530
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C+ VC C G+T +C ++DEC C + A C N PG Y C CR
Sbjct: 531 NGGACI---AANVCACPQGFTGP---SCETDIDECSDGFVQCDSRANCINLPGWYHCECR 584
Query: 439 DGYEGDGY------TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC-FTENCELSCSWQG 491
DGY +G +C +DEC G H+C + C N+DGG+ C C +NC C G
Sbjct: 585 DGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDG 644
Query: 492 RVVSEGATW 500
+V G W
Sbjct: 645 KVKHNGQIW 653
Score = 63.7 bits (148), Expect = 2e-09
Identities = 44/134 (32%), Positives = 62/134 (46%), Gaps = 24/134 (17%)
Query: 199 DCQKSCYSNGTVHADGATW--QRD-CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCP 255
+C C +G V +G W + D C+ CSC +G + CR + CD C+NP + CCP
Sbjct: 635 NCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCD---CENPTVDL-FCCP 690
Query: 256 TC----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C QCL LY G+ + + C +C C G + C L CP + C
Sbjct: 691 ECDPRLSSQCLHQNGETLYNSGDTWV-QNCQQCRCLQGEVDCW----PLPCPDVEC---- 741
Query: 310 QFSV--PGECCKFC 321
+FS+ ECC C
Sbjct: 742 EFSILPENECCPRC 755
Score = 62.9 bits (146), Expect = 3e-09
Identities = 39/122 (31%), Positives = 60/122 (49%), Gaps = 22/122 (18%)
Query: 197 QCDCQKS--C-YSNG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + S C + NG T++ G TW ++C +C C+ GE+ C P+ C EC+ +L E
Sbjct: 691 ECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDVECEFSILPENE 750
Query: 253 CCPTCL--------------RQCLLWGNLYEH-GERFAP--KECAECVCHDGNMQCTRVD 295
CCP C+ + CL N+ G + EC C C +G++ C VD
Sbjct: 751 CCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHI-CCSVD 809
Query: 296 PE 297
P+
Sbjct: 810 PQ 811
Score = 57.6 bits (133), Expect = 1e-07
Identities = 23/46 (50%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C HQ + SG+ W+ CQ C CL GEVDCW
Sbjct: 688 CCPECDPRLSSQCLHQN-GETLYNSGDTWVQNCQQCRCLQGEVDCW 732
>X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein.
Length = 3002
Score = 146 bits (353), Expect = 3e-34
Identities = 78/219 (35%), Positives = 110/219 (50%), Gaps = 28/219 (12%)
Query: 281 ECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE--C-C----------KFC 321
EC C G CT +D P + CD Q ++PGE C C K C
Sbjct: 1351 ECSCQPGFALMPDQRSCTDIDECEDNPNI-CDGGQCTNIPGEYRCLCYDGFMASEDMKTC 1409
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-GLT-CQDVDECQEAGGLHGHHCH 379
V+ C++ + + TC N + C C+ G+ G G T C D++EC+ + H+C
Sbjct: 1410 VDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECE----IGAHNCG 1465
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N G + C C G+ D C ++DEC TH C A C NT GSY C C++
Sbjct: 1466 KHAVCTNTAGSFKCSCSPGWIG-DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKE 1524
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY GDG+TC +DEC+E + C + +C+N GG+RCEC
Sbjct: 1525 GYTGDGFTCTDLDECSENLNLC-GNGQCLNAPGGYRCEC 1562
Score = 142 bits (343), Expect = 5e-33
Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 21/266 (7%)
Query: 223 RCSCVHG-EITCRPVEC-DRAECK-NPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPK 277
RC C G +++ C D EC+ + L P C + QC + +R
Sbjct: 1268 RCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1327
Query: 278 ECAECVCHDGNMQ--CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
+ EC +G + CT + C C P +P + + C +D C + +
Sbjct: 1328 DIDECSIMNGGCETFCTNSEGSYECS---CQPGFAL-MPDQ--RSCTDIDECEDNPNICD 1381
Query: 336 NATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N+ +Y C C GF D TC DV+EC L+ + C S T C N G ++C
Sbjct: 1382 GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECD----LNPNICLSGT-CENTKGSFIC 1436
Query: 394 QCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C GY+ +K K C +++ECE H C AVCTNT GS+ C C G+ GDG C +D
Sbjct: 1437 HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLD 1496
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC+ G+H C A C N G +RC C
Sbjct: 1497 ECSNGTHMCSQHADCKNTMGSYRCLC 1522
Score = 129 bits (311), Expect = 3e-29
Identities = 64/163 (39%), Positives = 91/163 (55%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHH 377
C ++ CN C N C N Y C C +G+ Q DG +C+D+DEC H+
Sbjct: 2573 CVDLNECNQAPKPC--NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDEC----ATKQHN 2626
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C CVN +GG+ C+C G+T+ +C++ +EC + + C + +C NTPGS+TC C
Sbjct: 2627 CQF--LCVNTIGGFTCKCPPGFTQHHT-SCIDNNECTSDINLCGSKGICQNTPGSFTCEC 2683
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G+ D G +C VDEC EG+H C H C NI GG+RC C
Sbjct: 2684 QRGFSLDQTGSSCEDVDEC-EGNHRCQHG--CQNIIGGYRCSC 2723
Score = 120 bits (289), Expect = 2e-26
Identities = 63/162 (38%), Positives = 83/162 (51%), Gaps = 13/162 (8%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C+ G H C ++A C N Y C C +G+ GDG TC D+DEC E L G
Sbjct: 1492 CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCG---- 1547
Query: 380 SNTRCVNVVGGYVCQC-LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N +C+N GGY C+C +G D C ++DEC + C N PG + C C
Sbjct: 1548 -NGQCLNAPGGYRCECDMGFVPSADGKACEDIDEC--SLPNICVFGTCHNLPGLFRCECE 1604
Query: 439 DGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE D G C V+EC + + TC S CVN G + C+C
Sbjct: 1605 IGYELDRSGGNCTDVNECLDPT-TC-ISGNCVNTPGSYICDC 1644
Score = 115 bits (277), Expect = 5e-25
Identities = 78/247 (31%), Positives = 109/247 (44%), Gaps = 34/247 (13%)
Query: 258 LRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCTRVDPELACPRLPCDPPQQF 311
+ +C + +L HG+ +C C G CT +D P L C Q
Sbjct: 1160 INECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL-CGRGQCV 1218
Query: 312 SVPG--EC-C-----------KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-- 355
+ PG EC C K C +D C C N Y C+C G Q
Sbjct: 1219 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1278
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECE 414
+ C D++EC+ L H C N RCVN++G Y C C GY + D+ CV++DEC
Sbjct: 1279 PNISACIDINECE----LSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS 1333
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDG 472
GC + CTN+ GSY C C+ G+ D +C +DEC + + C +C NI G
Sbjct: 1334 IMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIPG 1390
Query: 473 GFRCECF 479
+RC C+
Sbjct: 1391 EYRCLCY 1397
Score = 115 bits (277), Expect = 5e-25
Identities = 55/161 (34%), Positives = 83/161 (51%), Gaps = 11/161 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCH 379
C +D C G C NA C+N Y C C G++ C D +ECQE + C
Sbjct: 1937 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNI----C- 1991
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ +C++ VG + C C G+ T D+ C++++ECE + G + C NT GS+ CRC
Sbjct: 1992 SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACG---NGTCRNTIGSFNCRCN 2048
Query: 439 DGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ C+ VDEC G+ + +C+N G F+C+C
Sbjct: 2049 HGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 2089
Score = 111 bits (266), Expect = 1e-23
Identities = 66/184 (35%), Positives = 94/184 (51%), Gaps = 22/184 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT- 360
R C+ Q + GEC VD C + C C+N YTC+C G+Q LT
Sbjct: 604 RCECNKGFQLDLRGECID----VDECEK-NPC-AGGECINNQGSYTCQCRAGYQST-LTR 656
Query: 361 --CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNT 417
C+D+DEC + G + C+ N RC+N G + C C G+ +D NC ++DEC +
Sbjct: 657 TECRDIDECLQNGRI----CN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC--SI 709
Query: 418 HGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
+ +C N GS+ C C+ G++ DG C ++EC E C + RCVN DG +R
Sbjct: 710 RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNG-RCVNTDGSYR 767
Query: 476 CECF 479
CECF
Sbjct: 768 CECF 771
Score = 108 bits (259), Expect = 7e-23
Identities = 64/170 (37%), Positives = 80/170 (47%), Gaps = 11/170 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF-QGDGLTCQDVDECQEAGGLHGHHCH 379
C ++ C +C N TC N + C+CN GF C DVDEC A G +G+ C
Sbjct: 2020 CLDINECERD-ACG-NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDEC--ASG-NGNLCR 2074
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N +C+N VG + CQC GY D CV+++EC C A C N GSY C C
Sbjct: 2075 -NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC-APGTCQNLDGSYRCICP 2132
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
GY C +DEC E C C N +G F+C C E LS S
Sbjct: 2133 PGYSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLC-PEGFSLSSS 2180
Score = 107 bits (256), Expect = 2e-22
Identities = 54/158 (34%), Positives = 75/158 (47%), Gaps = 11/158 (6%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
+D C + H N C+N Y C C G+ D G +C D++EC +A C N
Sbjct: 2534 IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAP----KPC--N 2587
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C GY ++D +C ++DEC H C +C NT G +TC+C G
Sbjct: 2588 FICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCKCPPG 2645
Query: 441 YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +C+ +ECT + C C N G F CEC
Sbjct: 2646 FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCEC 2683
Score = 105 bits (252), Expect = 5e-22
Identities = 54/151 (35%), Positives = 78/151 (51%), Gaps = 16/151 (10%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C C N +TC+C +GF D G +C+DVDEC+ H C C N++GG
Sbjct: 2666 CGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEG-----NHRCQHG--CQNIIGG 2718
Query: 391 YVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-- 447
Y C C GY + ++N CV+ +EC + H C A C NT GSY C C G++ + ++
Sbjct: 2719 YRCSCPQGYLQHYQWNQCVDENECL-SAHIC-GGASCHNTLGSYKCMCPAGFQYEQFSGG 2776
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C ++EC C + C N +GG+ C C
Sbjct: 2777 CQDINECGSAQAPCSYG--CSNTEGGYLCGC 2805
Score = 104 bits (249), Expect = 1e-21
Identities = 64/186 (34%), Positives = 93/186 (50%), Gaps = 18/186 (9%)
Query: 301 PRLPCD-PPQQFSVPG-ECCKFCPG--VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG 356
P++P PP ++ P E + P DYC + +N C+ Y C+CN+GFQ
Sbjct: 554 PQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSYRCECNKGFQL 613
Query: 357 D-GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECE 414
D C DVDEC++ + C + C+N G Y CQC GY + + C ++DEC
Sbjct: 614 DLRGECIDVDECEK------NPC-AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECL 666
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDG 472
N C+ + C NT GS+ C C G+ DG C +DEC+ + C + C+N DG
Sbjct: 667 QNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI-RNMC-LNGMCINEDG 723
Query: 473 GFRCEC 478
F+C C
Sbjct: 724 SFKCIC 729
Score = 103 bits (248), Expect = 2e-21
Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 31/211 (14%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGEC-----CKFCPGVDYCNMGHS 332
EC N +C C C P +F+ G+C C+ P + C+ G
Sbjct: 1942 ECQNGPVCQRNAECINTAGSYRCD---CKPGYRFTSTGQCNDRNECQEIPNI--CSHGQ- 1995
Query: 333 CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C++ + C C+ GF+ D C D++EC+ C + T C N +G
Sbjct: 1996 ------CIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDA------CGNGT-CRNTIGS 2042
Query: 391 YVCQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYT 447
+ C+C G+ +C++VDEC GN + C + C NT GS+ C+C +GYE DG T
Sbjct: 2043 FNCRCNHGFILSHNNDCIDVDECASGNGNLCR-NGQCINTVGSFQCQCNEGYEVAPDGRT 2101
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+ ++EC C C N+DG +RC C
Sbjct: 2102 CVDINECLLEPRKC-APGTCQNLDGSYRCIC 2131
Score = 103 bits (247), Expect = 2e-21
Identities = 68/214 (31%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG 330
G + +EC EC M+ T EL CPR P ++ + G+ F ++ C M
Sbjct: 1116 GAAWGTEECEECP-----MRNTPEYEEL-CPRGPGFATKEIT-NGK--PFFKDINECKMI 1166
Query: 331 HSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
S + C N + C+C+ GF D C D+DEC+ + L G +CVN
Sbjct: 1167 PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCG-----RGQCVNTP 1221
Query: 389 GGYVCQCLGGYTRKDKF--NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GD 444
G + C+C GY NC+++DEC+ + C VC NT GSY C C G++ +
Sbjct: 1222 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPN 1280
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+ ++EC +H C + RCVN+ G ++C C
Sbjct: 1281 ISACIDINECELSAHLC-PNGRCVNLIGKYQCAC 1313
Score = 100 bits (240), Expect = 1e-20
Identities = 55/158 (34%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C C ++ C+N + Y C+C G+ G C D DEC G+ C + T
Sbjct: 2259 MDECKEPDVC-KHGQCINTDGSYRCECPFGYTLAGNECVDTDECSV-----GNPCGNGT- 2311
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY-- 441
C NV+GG+ C C G+ C +++EC N C C NT GSY C+C GY
Sbjct: 2312 CKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYGSYECKCPVGYVL 2369
Query: 442 EGDGYTCMHVDECTEGSHTC-HHSARCVNIDGGFRCEC 478
D C DEC EG H C C N+ G + C C
Sbjct: 2370 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCIC 2407
Score = 93.9 bits (223), Expect = 2e-18
Identities = 50/159 (31%), Positives = 73/159 (45%), Gaps = 13/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSN 381
+D C EN C+N+ + C+C GF L C+D+DECQ +G C N
Sbjct: 1898 IDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-----NGPVCQRN 1952
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N G Y C C GY C + +EC+ + C + C +T GS+ C C G+
Sbjct: 1953 AECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGF 2011
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ D C+ ++EC + C + C N G F C C
Sbjct: 2012 KTNDDQTMCLDINECERDA--CGNGT-CRNTIGSFNCRC 2047
Score = 87.0 bits (206), Expect = 2e-16
Identities = 45/120 (37%), Positives = 64/120 (53%), Gaps = 9/120 (7%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCH 421
D+DEC+E G+ C + C+N+VG + C+C G+ DK C ++DEC+ N C
Sbjct: 1897 DIDECREIPGV----CENGV-CINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQ 1950
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+A C NT GSY C C+ GY C +EC E + C H +C++ G F C C T
Sbjct: 1951 RNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSH-GQCIDTVGSFYCLCHT 2009
Score = 81.8 bits (193), Expect = 7e-15
Identities = 59/170 (34%), Positives = 78/170 (45%), Gaps = 18/170 (10%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHG 375
ECC C +Y G C + N + +Y C+ G G D++EC L
Sbjct: 813 ECC--CASTEYA-FGEPC-QPCPAQN-SAEYQALCSSG-PGMTSAGSDINEC----ALDP 862
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
C N C N+ G Y C C GY NCV+++EC N+ C + C NTPGS+
Sbjct: 863 DIC-PNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCD-NGQCRNTPGSFV 920
Query: 435 CRCRDG--YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTEN 482
C C G Y+ D TC +DEC S C + C N G F CEC +E+
Sbjct: 921 CTCPKGFIYKPDLKTCEDIDECE--SSPCINGV-CKNSPGSFICECSSES 967
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/146 (34%), Positives = 69/146 (47%), Gaps = 20/146 (13%)
Query: 304 PCDP-PQQFSVPGEC-CKFCPG-------VDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
PC P P Q S + C PG ++ C + N C NL Y C CN G+
Sbjct: 826 PCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGY 885
Query: 355 QGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVD 411
+ D G C D++EC L+ C N +C N G +VC C G+ K D C ++D
Sbjct: 886 EVDSTGKNCVDINECV----LNSLLC-DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID 940
Query: 412 ECEGNTHGCHADAVCTNTPGSYTCRC 437
ECE + C + VC N+PGS+ C C
Sbjct: 941 ECESSP--C-INGVCKNSPGSFICEC 963
Score = 75.8 bits (178), Expect = 5e-13
Identities = 62/207 (29%), Positives = 83/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPT--CLR-QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT R +C L GE EC + C G +C C C
Sbjct: 594 GRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGG--ECINNQGSYTCQ---CRA 648
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q ++ C+ +D C N C+N + + C CN GF DG C+D+D
Sbjct: 649 GYQSTLTRTECR---DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMD 705
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ D C +++ECE T G +
Sbjct: 706 ECSIR-----NMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE--TPGICMNG 757
Query: 425 VCTNTPGSYTCRCRDGYEG--DGYTCM 449
C NT GSY C C G DG C+
Sbjct: 758 RCVNTDGSYRCECFPGLAVGLDGRVCV 784
Score = 74.9 bits (176), Expect = 8e-13
Identities = 44/125 (35%), Positives = 60/125 (48%), Gaps = 11/125 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C+ + N C+N Y C+C+ GF DG C+D+DEC + C
Sbjct: 1533 CTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLP-----NIC 1587
Query: 379 HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
T C N+ G + C+C GY + NC +V+EC T C C NTPGSY C C
Sbjct: 1588 VFGT-CHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPT-TC-ISGNCVNTPGSYICDC 1644
Query: 438 RDGYE 442
+E
Sbjct: 1645 PPDFE 1649
Score = 70.1 bits (164), Expect = 2e-11
Identities = 74/259 (28%), Positives = 94/259 (36%), Gaps = 32/259 (12%)
Query: 221 CNRCSCVHGEITC-RPVECDRAECKNPVLHPGECC--PTCLRQCLLWGNLYEHGERFAPK 277
C S H I C C C + G C P C CL G AP
Sbjct: 242 CGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCL------NGGRCVAPN 295
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK--FCPGVDYCNMGHSCDE 335
CA C QC R C + + Q + G C C GH C+
Sbjct: 296 RCA-CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCE- 353
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
+ C +GF + T CQDVDECQ GL C C+N VG + C
Sbjct: 354 ------MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGL----CQGGN-CINTVGSFEC 402
Query: 394 QCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMH 450
+C G+ + C ++DEC C CTNT SY C+C G+ DG C
Sbjct: 403 KCPAGHKLNEVSQKCEDIDECSTIPGICEGGE-CTNTVSSYFCKCPPGFYTSPDGTRC-- 459
Query: 451 VDECTEGSHTCHHSARCVN 469
+D +T + RC N
Sbjct: 460 IDVRPGYCYTALTNGRCSN 478
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/119 (36%), Positives = 59/119 (49%), Gaps = 15/119 (12%)
Query: 339 CMNLNT---KYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C +NT K C +GF+ + +T +D+DECQE GL C +C+N G + C
Sbjct: 1708 CPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL----CQGG-KCINTFGSFQC 1762
Query: 394 QC-LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCM 449
+C G Y +D C +V+ECE T G C NT G+YTC C Y G CM
Sbjct: 1763 RCPTGYYLNEDTRVCDDVNECE--TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM 1819
Score = 69.3 bits (162), Expect = 4e-11
Identities = 44/141 (31%), Positives = 61/141 (43%), Gaps = 16/141 (11%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQ 362
C+ + FS+ + C VD C H C C N+ Y C C QG+ C
Sbjct: 2681 CECQRGFSLD-QTGSSCEDVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCV 2737
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGC 420
D +EC A G CH N +G Y C C G+ + ++F+ C +++EC C
Sbjct: 2738 DENECLSAHICGGASCH------NTLGSYKCMCPAGF-QYEQFSGGCQDINECGSAQAPC 2790
Query: 421 HADAVCTNTPGSYTCRCRDGY 441
C+NT G Y C C GY
Sbjct: 2791 SYG--CSNTEGGYLCGCPPGY 2809
Score = 67.7 bits (158), Expect = 1e-10
Identities = 76/291 (26%), Positives = 109/291 (37%), Gaps = 46/291 (15%)
Query: 224 CSCVHGEITCRPVEC-DRAEC-KNPVLHPGECCPTC-LRQCLLWGNLYEHGERFAPKECA 280
C+C G + C D EC +NP+L C T +C +R K+
Sbjct: 2321 CTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKD-- 2378
Query: 281 ECVCHDGNMQCTRVDPELACPRLP------CDPPQQFSVPGECCKFCPGVDYCNMGHSCD 334
E C +G CT + ++ C L C P Q GE C + C
Sbjct: 2379 EDECEEGKHDCT--EKQMECKNLIGTYMCICGPGYQRRPDGEGCV---DENECQTKPGIC 2433
Query: 335 ENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
EN C+N YTC+CN GF + C D E + + C + N V
Sbjct: 2434 ENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSE 2493
Query: 393 CQCLGG-----------------------YTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
C C GG + R N ++DEC+ H + C N
Sbjct: 2494 CCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECK-VIHDVCRNGECVND 2552
Query: 430 PGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GSY C C+ GY D G +C+ ++EC + C+ C N +G ++C C
Sbjct: 2553 RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFI--CKNTEGSYQCSC 2601
Score = 66.9 bits (156), Expect = 2e-10
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 33/185 (17%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
K C ++ C + +N C N + C C +GF + D TC+D+DEC+ + ++G
Sbjct: 892 KNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGV 951
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVE----------VD-ECEGNTHGCHADA 424
C N G ++C+C T K C+E +D CE N +G +
Sbjct: 952 -------CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKS 1004
Query: 425 VCTNTPGSY------TCR----CRDGYEG-DGYTCMHVDECTEGSHTCHHSARCVNIDGG 473
C ++ G+ C+ C GY G C +DEC C + CVN G
Sbjct: 1005 QCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGL-CVNTRGS 1063
Query: 474 FRCEC 478
F+C+C
Sbjct: 1064 FKCQC 1068
Score = 66.5 bits (155), Expect = 3e-10
Identities = 79/308 (25%), Positives = 112/308 (36%), Gaps = 58/308 (18%)
Query: 220 DCNRCSCVHGEITCR-PVECDRAECKNPVL--HPGECCPTCLRQCLLW-GNLYEHGERFA 275
+C R +C +G TCR + C + + H +C + +C GNL +G+
Sbjct: 2025 ECERDACGNG--TCRNTIGSFNCRCNHGFILSHNNDCID--VDECASGNGNLCRNGQCIN 2080
Query: 276 PKECAECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCP-GV---- 324
+C C++G C ++ L PR C P ++ G CP G
Sbjct: 2081 TVGSFQCQCNEGYEVAPDGRTCVDINECLLEPR-KCAPGTCQNLDGSYRCICPPGYSLQN 2139
Query: 325 DYCNMGHSCDEN------ATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
+ C C E TC N + C C +GF G CQD+ G
Sbjct: 2140 EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGG 2199
Query: 377 HC-------HSNTRCVNVVGG-------------------YVCQCLGGYTRKDKFNCVEV 410
C HS C + G +C G + V++
Sbjct: 2200 KCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDM 2259
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNI 470
DEC+ H C NT GSY C C GY G C+ DEC+ G + C + C N+
Sbjct: 2260 DECKEPDVCKHGQ--CINTDGSYRCECPFGYTLAGNECVDTDECSVG-NPCGNGT-CKNV 2315
Query: 471 DGGFRCEC 478
GGF C C
Sbjct: 2316 IGGFECTC 2323
Score = 54.8 bits (126), Expect = 9e-07
Identities = 33/90 (36%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHC 378
C + C H C A+C N Y C C GFQ + + CQD++EC A + C
Sbjct: 2736 CVDENECLSAHICG-GASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGC 2794
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
SNT GGY+C C GY R + +CV
Sbjct: 2795 -SNTE-----GGYLCGCPPGYFRIGQGHCV 2818
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/225 (25%), Positives = 81/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP-GECCKFCPG--VDYC 327
G R+ C G QC +C C P + P G+ C + +C
Sbjct: 191 GSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 250
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
N+ C +C + + C C +G+ G Q V C E+G L+G C + RC
Sbjct: 251 NI--RCMNGGSCSDDH----CLCQKGYIGTHCG-QPV--C-ESGCLNGGRCVAPNRCACT 300
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG-CHADAVCTNTPG---SYTCR------- 436
G QC Y F + C+G G +C T G + C
Sbjct: 301 YGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH 360
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + T C VDEC C C+N G F C+C
Sbjct: 361 PCRRGFIPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKC 404
Score = 43.2 bits (97), Expect = 0.003
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ CRC GY D C V+EC E C
Sbjct: 1737 DIDECQELPGLCQGGK-CINTFGSFQCRCPTGYYLNEDTRVCDDVNEC-ETPGIC-GPGT 1793
Query: 467 CVNIDGGFRCEC 478
C N G + C C
Sbjct: 1794 CYNTVGNYTCIC 1805
Score = 43.2 bits (97), Expect = 0.003
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 9/90 (10%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ D C DV+EC+ G C
Sbjct: 1738 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG-----ICGPG 1792
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N VG Y C C Y + NC+++
Sbjct: 1793 T-CYNTVGNYTCICPPDYMQVNGGNNCMDM 1821
Score = 41.9 bits (94), Expect = 0.007
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHV 451
C GY+R C ++DECE C + +C NT GS+ C+C G + G C+ +
Sbjct: 1027 CGKGYSRIKGTQCEDIDECEVFPGVCK-NGLCVNTRGSFKCQCPSGMTLDATGRICLDI 1084
Score = 39.5 bits (88), Expect = 0.037
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 350 CNQGFQG-DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
C +G+ G C+D+DEC+ G+ C N CVN G + CQC G T
Sbjct: 1027 CGKGYSRIKGTQCEDIDECEVFPGV----C-KNGLCVNTRGSFKCQCPSGMT 1073
Score = 33.9 bits (74), Expect = 1.8
Identities = 35/162 (21%), Positives = 55/162 (33%), Gaps = 13/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C +C + C+N Y C C F+ + VD +C+
Sbjct: 1616 CTDVNECLDPTTCI-SGNCVNTPGSYICDCPPDFELNPTRVGCVDT-------RSGNCYL 1667
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
+ R G C G C + + G C + C +G
Sbjct: 1668 DIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTP--CEMCPAVNTSEYKILCPGGEG 1725
Query: 441 YEGDGYTCM--HVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ + T + +DEC E C +C+N G F+C C T
Sbjct: 1726 FRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCRCPT 1766
>L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein.
Length = 2871
Score = 146 bits (353), Expect = 3e-34
Identities = 78/219 (35%), Positives = 110/219 (50%), Gaps = 28/219 (12%)
Query: 281 ECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE--C-C----------KFC 321
EC C G CT +D P + CD Q ++PGE C C K C
Sbjct: 1220 ECSCQPGFALMPDQRSCTDIDECEDNPNI-CDGGQCTNIPGEYRCLCYDGFMASEDMKTC 1278
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-GLT-CQDVDECQEAGGLHGHHCH 379
V+ C++ + + TC N + C C+ G+ G G T C D++EC+ + H+C
Sbjct: 1279 VDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECE----IGAHNCG 1334
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N G + C C G+ D C ++DEC TH C A C NT GSY C C++
Sbjct: 1335 KHAVCTNTAGSFKCSCSPGWIG-DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKE 1393
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY GDG+TC +DEC+E + C + +C+N GG+RCEC
Sbjct: 1394 GYTGDGFTCTDLDECSENLNLC-GNGQCLNAPGGYRCEC 1431
Score = 142 bits (343), Expect = 5e-33
Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 21/266 (7%)
Query: 223 RCSCVHG-EITCRPVEC-DRAECK-NPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPK 277
RC C G +++ C D EC+ + L P C + QC + +R
Sbjct: 1137 RCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Query: 278 ECAECVCHDGNMQ--CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
+ EC +G + CT + C C P +P + + C +D C + +
Sbjct: 1197 DIDECSIMNGGCETFCTNSEGSYECS---CQPGFAL-MPDQ--RSCTDIDECEDNPNICD 1250
Query: 336 NATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N+ +Y C C GF D TC DV+EC L+ + C S T C N G ++C
Sbjct: 1251 GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECD----LNPNICLSGT-CENTKGSFIC 1305
Query: 394 QCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C GY+ +K K C +++ECE H C AVCTNT GS+ C C G+ GDG C +D
Sbjct: 1306 HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLD 1365
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC+ G+H C A C N G +RC C
Sbjct: 1366 ECSNGTHMCSQHADCKNTMGSYRCLC 1391
Score = 129 bits (311), Expect = 3e-29
Identities = 64/163 (39%), Positives = 91/163 (55%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHH 377
C ++ CN C N C N Y C C +G+ Q DG +C+D+DEC H+
Sbjct: 2442 CVDLNECNQAPKPC--NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDEC----ATKQHN 2495
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C CVN +GG+ C+C G+T+ +C++ +EC + + C + +C NTPGS+TC C
Sbjct: 2496 CQF--LCVNTIGGFTCKCPPGFTQHHT-SCIDNNECTSDINLCGSKGICQNTPGSFTCEC 2552
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G+ D G +C VDEC EG+H C H C NI GG+RC C
Sbjct: 2553 QRGFSLDQTGSSCEDVDEC-EGNHRCQHG--CQNIIGGYRCSC 2592
Score = 120 bits (289), Expect = 2e-26
Identities = 63/162 (38%), Positives = 83/162 (51%), Gaps = 13/162 (8%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C+ G H C ++A C N Y C C +G+ GDG TC D+DEC E L G
Sbjct: 1361 CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCG---- 1416
Query: 380 SNTRCVNVVGGYVCQC-LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N +C+N GGY C+C +G D C ++DEC + C N PG + C C
Sbjct: 1417 -NGQCLNAPGGYRCECDMGFVPSADGKACEDIDEC--SLPNICVFGTCHNLPGLFRCECE 1473
Query: 439 DGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE D G C V+EC + + TC S CVN G + C+C
Sbjct: 1474 IGYELDRSGGNCTDVNECLDPT-TC-ISGNCVNTPGSYICDC 1513
Score = 115 bits (277), Expect = 5e-25
Identities = 78/247 (31%), Positives = 109/247 (44%), Gaps = 34/247 (13%)
Query: 258 LRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCTRVDPELACPRLPCDPPQQF 311
+ +C + +L HG+ +C C G CT +D P L C Q
Sbjct: 1029 INECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL-CGRGQCV 1087
Query: 312 SVPG--EC-C-----------KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-- 355
+ PG EC C K C +D C C N Y C+C G Q
Sbjct: 1088 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1147
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECE 414
+ C D++EC+ L H C N RCVN++G Y C C GY + D+ CV++DEC
Sbjct: 1148 PNISACIDINECE----LSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS 1202
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDG 472
GC + CTN+ GSY C C+ G+ D +C +DEC + + C +C NI G
Sbjct: 1203 IMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIPG 1259
Query: 473 GFRCECF 479
+RC C+
Sbjct: 1260 EYRCLCY 1266
Score = 115 bits (277), Expect = 5e-25
Identities = 55/161 (34%), Positives = 83/161 (51%), Gaps = 11/161 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCH 379
C +D C G C NA C+N Y C C G++ C D +ECQE + C
Sbjct: 1806 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNI----C- 1860
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ +C++ VG + C C G+ T D+ C++++ECE + G + C NT GS+ CRC
Sbjct: 1861 SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACG---NGTCRNTIGSFNCRCN 1917
Query: 439 DGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ C+ VDEC G+ + +C+N G F+C+C
Sbjct: 1918 HGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 1958
Score = 111 bits (266), Expect = 1e-23
Identities = 66/184 (35%), Positives = 94/184 (51%), Gaps = 22/184 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT- 360
R C+ Q + GEC VD C + C C+N YTC+C G+Q LT
Sbjct: 473 RCECNKGFQLDLRGECID----VDECEK-NPC-AGGECINNQGSYTCQCRAGYQST-LTR 525
Query: 361 --CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNT 417
C+D+DEC + G + C+ N RC+N G + C C G+ +D NC ++DEC +
Sbjct: 526 TECRDIDECLQNGRI----CN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC--SI 578
Query: 418 HGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
+ +C N GS+ C C+ G++ DG C ++EC E C + RCVN DG +R
Sbjct: 579 RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNG-RCVNTDGSYR 636
Query: 476 CECF 479
CECF
Sbjct: 637 CECF 640
Score = 108 bits (259), Expect = 7e-23
Identities = 64/170 (37%), Positives = 80/170 (47%), Gaps = 11/170 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF-QGDGLTCQDVDECQEAGGLHGHHCH 379
C ++ C +C N TC N + C+CN GF C DVDEC A G +G+ C
Sbjct: 1889 CLDINECERD-ACG-NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDEC--ASG-NGNLCR 1943
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N +C+N VG + CQC GY D CV+++EC C A C N GSY C C
Sbjct: 1944 -NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC-APGTCQNLDGSYRCICP 2001
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
GY C +DEC E C C N +G F+C C E LS S
Sbjct: 2002 PGYSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLC-PEGFSLSSS 2049
Score = 107 bits (256), Expect = 2e-22
Identities = 54/158 (34%), Positives = 75/158 (47%), Gaps = 11/158 (6%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
+D C + H N C+N Y C C G+ D G +C D++EC +A C N
Sbjct: 2403 IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAP----KPC--N 2456
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C GY ++D +C ++DEC H C +C NT G +TC+C G
Sbjct: 2457 FICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCKCPPG 2514
Query: 441 YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +C+ +ECT + C C N G F CEC
Sbjct: 2515 FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCEC 2552
Score = 105 bits (252), Expect = 5e-22
Identities = 54/151 (35%), Positives = 78/151 (51%), Gaps = 16/151 (10%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C C N +TC+C +GF D G +C+DVDEC+ H C C N++GG
Sbjct: 2535 CGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEG-----NHRCQHG--CQNIIGG 2587
Query: 391 YVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-- 447
Y C C GY + ++N CV+ +EC + H C A C NT GSY C C G++ + ++
Sbjct: 2588 YRCSCPQGYLQHYQWNQCVDENECL-SAHIC-GGASCHNTLGSYKCMCPAGFQYEQFSGG 2645
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C ++EC C + C N +GG+ C C
Sbjct: 2646 CQDINECGSAQAPCSYG--CSNTEGGYLCGC 2674
Score = 104 bits (249), Expect = 1e-21
Identities = 64/186 (34%), Positives = 93/186 (50%), Gaps = 18/186 (9%)
Query: 301 PRLPCD-PPQQFSVPG-ECCKFCPG--VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG 356
P++P PP ++ P E + P DYC + +N C+ Y C+CN+GFQ
Sbjct: 423 PQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSYRCECNKGFQL 482
Query: 357 D-GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECE 414
D C DVDEC++ + C + C+N G Y CQC GY + + C ++DEC
Sbjct: 483 DLRGECIDVDECEK------NPC-AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECL 535
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDG 472
N C+ + C NT GS+ C C G+ DG C +DEC+ + C + C+N DG
Sbjct: 536 QNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI-RNMC-LNGMCINEDG 592
Query: 473 GFRCEC 478
F+C C
Sbjct: 593 SFKCIC 598
Score = 103 bits (248), Expect = 2e-21
Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 31/211 (14%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGEC-----CKFCPGVDYCNMGHS 332
EC N +C C C P +F+ G+C C+ P + C+ G
Sbjct: 1811 ECQNGPVCQRNAECINTAGSYRCD---CKPGYRFTSTGQCNDRNECQEIPNI--CSHGQ- 1864
Query: 333 CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C++ + C C+ GF+ D C D++EC+ C + T C N +G
Sbjct: 1865 ------CIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDA------CGNGT-CRNTIGS 1911
Query: 391 YVCQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYT 447
+ C+C G+ +C++VDEC GN + C + C NT GS+ C+C +GYE DG T
Sbjct: 1912 FNCRCNHGFILSHNNDCIDVDECASGNGNLCR-NGQCINTVGSFQCQCNEGYEVAPDGRT 1970
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+ ++EC C C N+DG +RC C
Sbjct: 1971 CVDINECLLEPRKC-APGTCQNLDGSYRCIC 2000
Score = 103 bits (247), Expect = 2e-21
Identities = 68/214 (31%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG 330
G + +EC EC M+ T EL CPR P ++ + G+ F ++ C M
Sbjct: 985 GAAWGTEECEECP-----MRNTPEYEEL-CPRGPGFATKEIT-NGK--PFFKDINECKMI 1035
Query: 331 HSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
S + C N + C+C+ GF D C D+DEC+ + L G +CVN
Sbjct: 1036 PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCG-----RGQCVNTP 1090
Query: 389 GGYVCQCLGGYTRKDKF--NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GD 444
G + C+C GY NC+++DEC+ + C VC NT GSY C C G++ +
Sbjct: 1091 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPN 1149
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+ ++EC +H C + RCVN+ G ++C C
Sbjct: 1150 ISACIDINECELSAHLC-PNGRCVNLIGKYQCAC 1182
Score = 100 bits (240), Expect = 1e-20
Identities = 55/158 (34%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C C ++ C+N + Y C+C G+ G C D DEC G+ C + T
Sbjct: 2128 MDECKEPDVC-KHGQCINTDGSYRCECPFGYTLAGNECVDTDECSV-----GNPCGNGT- 2180
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY-- 441
C NV+GG+ C C G+ C +++EC N C C NT GSY C+C GY
Sbjct: 2181 CKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYGSYECKCPVGYVL 2238
Query: 442 EGDGYTCMHVDECTEGSHTC-HHSARCVNIDGGFRCEC 478
D C DEC EG H C C N+ G + C C
Sbjct: 2239 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCIC 2276
Score = 93.9 bits (223), Expect = 2e-18
Identities = 50/159 (31%), Positives = 73/159 (45%), Gaps = 13/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSN 381
+D C EN C+N+ + C+C GF L C+D+DECQ +G C N
Sbjct: 1767 IDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-----NGPVCQRN 1821
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N G Y C C GY C + +EC+ + C + C +T GS+ C C G+
Sbjct: 1822 AECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGF 1880
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ D C+ ++EC + C + C N G F C C
Sbjct: 1881 KTNDDQTMCLDINECERDA--CGNGT-CRNTIGSFNCRC 1916
Score = 87.0 bits (206), Expect = 2e-16
Identities = 45/120 (37%), Positives = 64/120 (53%), Gaps = 9/120 (7%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCH 421
D+DEC+E G+ C + C+N+VG + C+C G+ DK C ++DEC+ N C
Sbjct: 1766 DIDECREIPGV----CENGV-CINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQ 1819
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+A C NT GSY C C+ GY C +EC E + C H +C++ G F C C T
Sbjct: 1820 RNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSH-GQCIDTVGSFYCLCHT 1878
Score = 81.8 bits (193), Expect = 7e-15
Identities = 59/170 (34%), Positives = 78/170 (45%), Gaps = 18/170 (10%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHG 375
ECC C +Y G C + N + +Y C+ G G D++EC L
Sbjct: 682 ECC--CASTEYA-FGEPC-QPCPAQN-SAEYQALCSSG-PGMTSAGSDINEC----ALDP 731
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
C N C N+ G Y C C GY NCV+++EC N+ C + C NTPGS+
Sbjct: 732 DIC-PNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCD-NGQCRNTPGSFV 789
Query: 435 CRCRDG--YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTEN 482
C C G Y+ D TC +DEC S C + C N G F CEC +E+
Sbjct: 790 CTCPKGFIYKPDLKTCEDIDECE--SSPCINGV-CKNSPGSFICECSSES 836
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/146 (34%), Positives = 69/146 (47%), Gaps = 20/146 (13%)
Query: 304 PCDP-PQQFSVPGEC-CKFCPG-------VDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
PC P P Q S + C PG ++ C + N C NL Y C CN G+
Sbjct: 695 PCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGY 754
Query: 355 QGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVD 411
+ D G C D++EC L+ C N +C N G +VC C G+ K D C ++D
Sbjct: 755 EVDSTGKNCVDINECV----LNSLLC-DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID 809
Query: 412 ECEGNTHGCHADAVCTNTPGSYTCRC 437
ECE + C + VC N+PGS+ C C
Sbjct: 810 ECESSP--C-INGVCKNSPGSFICEC 832
Score = 75.8 bits (178), Expect = 5e-13
Identities = 62/207 (29%), Positives = 83/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPT--CLR-QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT R +C L GE EC + C G +C C C
Sbjct: 463 GRCIPTPGSYRCECNKGFQLDLRGECIDVDECEKNPCAGG--ECINNQGSYTCQ---CRA 517
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q ++ C+ +D C N C+N + + C CN GF DG C+D+D
Sbjct: 518 GYQSTLTRTECR---DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMD 574
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ D C +++ECE T G +
Sbjct: 575 ECSIR-----NMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE--TPGICMNG 626
Query: 425 VCTNTPGSYTCRCRDGYEG--DGYTCM 449
C NT GSY C C G DG C+
Sbjct: 627 RCVNTDGSYRCECFPGLAVGLDGRVCV 653
Score = 74.9 bits (176), Expect = 8e-13
Identities = 44/125 (35%), Positives = 60/125 (48%), Gaps = 11/125 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C+ + N C+N Y C+C+ GF DG C+D+DEC + C
Sbjct: 1402 CTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLP-----NIC 1456
Query: 379 HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
T C N+ G + C+C GY + NC +V+EC T C C NTPGSY C C
Sbjct: 1457 VFGT-CHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPT-TC-ISGNCVNTPGSYICDC 1513
Query: 438 RDGYE 442
+E
Sbjct: 1514 PPDFE 1518
Score = 70.9 bits (166), Expect = 1e-11
Identities = 74/259 (28%), Positives = 95/259 (36%), Gaps = 32/259 (12%)
Query: 221 CNRCSCVHGEITC-RPVECDRAECKNPVLHPGECC--PTCLRQCLLWGNLYEHGERFAPK 277
C S H I C C C + G C P C CL G AP
Sbjct: 111 CGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCL------NGGRCVAPN 164
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECC--KFCPGVDYCNMGHSCDE 335
CA C QC R C + + Q + G C + C GH C+
Sbjct: 165 RCA-CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKQLCCATVGRAWGHPCE- 222
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
+ C +GF + T CQDVDECQ GL C C+N VG + C
Sbjct: 223 ------MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGL----CQGGN-CINTVGSFEC 271
Query: 394 QCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMH 450
+C G+ + C ++DEC C CTNT SY C+C G+ DG C
Sbjct: 272 KCPAGHKLNEVSQKCEDIDECSTIPGICEGGE-CTNTVSSYFCKCPPGFYTSPDGTRC-- 328
Query: 451 VDECTEGSHTCHHSARCVN 469
+D +T + RC N
Sbjct: 329 IDVRPGYCYTALTNGRCSN 347
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/119 (36%), Positives = 59/119 (49%), Gaps = 15/119 (12%)
Query: 339 CMNLNT---KYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C +NT K C +GF+ + +T +D+DECQE GL C +C+N G + C
Sbjct: 1577 CPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL----CQGG-KCINTFGSFQC 1631
Query: 394 QC-LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCM 449
+C G Y +D C +V+ECE T G C NT G+YTC C Y G CM
Sbjct: 1632 RCPTGYYLNEDTRVCDDVNECE--TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM 1688
Score = 69.3 bits (162), Expect = 4e-11
Identities = 44/141 (31%), Positives = 61/141 (43%), Gaps = 16/141 (11%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQ 362
C+ + FS+ + C VD C H C C N+ Y C C QG+ C
Sbjct: 2550 CECQRGFSLD-QTGSSCEDVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCV 2606
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGC 420
D +EC A G CH N +G Y C C G+ + ++F+ C +++EC C
Sbjct: 2607 DENECLSAHICGGASCH------NTLGSYKCMCPAGF-QYEQFSGGCQDINECGSAQAPC 2659
Query: 421 HADAVCTNTPGSYTCRCRDGY 441
C+NT G Y C C GY
Sbjct: 2660 SYG--CSNTEGGYLCGCPPGY 2678
Score = 67.7 bits (158), Expect = 1e-10
Identities = 76/291 (26%), Positives = 109/291 (37%), Gaps = 46/291 (15%)
Query: 224 CSCVHGEITCRPVEC-DRAEC-KNPVLHPGECCPTC-LRQCLLWGNLYEHGERFAPKECA 280
C+C G + C D EC +NP+L C T +C +R K+
Sbjct: 2190 CTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKD-- 2247
Query: 281 ECVCHDGNMQCTRVDPELACPRLP------CDPPQQFSVPGECCKFCPGVDYCNMGHSCD 334
E C +G CT + ++ C L C P Q GE C + C
Sbjct: 2248 EDECEEGKHDCT--EKQMECKNLIGTYMCICGPGYQRRPDGEGCV---DENECQTKPGIC 2302
Query: 335 ENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
EN C+N YTC+CN GF + C D E + + C + N V
Sbjct: 2303 ENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSE 2362
Query: 393 CQCLGG-----------------------YTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
C C GG + R N ++DEC+ H + C N
Sbjct: 2363 CCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECK-VIHDVCRNGECVND 2421
Query: 430 PGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GSY C C+ GY D G +C+ ++EC + C+ C N +G ++C C
Sbjct: 2422 RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFI--CKNTEGSYQCSC 2470
Score = 66.9 bits (156), Expect = 2e-10
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 33/185 (17%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
K C ++ C + +N C N + C C +GF + D TC+D+DEC+ + ++G
Sbjct: 761 KNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGV 820
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVE----------VD-ECEGNTHGCHADA 424
C N G ++C+C T K C+E +D CE N +G +
Sbjct: 821 -------CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKS 873
Query: 425 VCTNTPGSY------TCR----CRDGYEG-DGYTCMHVDECTEGSHTCHHSARCVNIDGG 473
C ++ G+ C+ C GY G C +DEC C + CVN G
Sbjct: 874 QCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGL-CVNTRGS 932
Query: 474 FRCEC 478
F+C+C
Sbjct: 933 FKCQC 937
Score = 66.5 bits (155), Expect = 3e-10
Identities = 79/308 (25%), Positives = 112/308 (36%), Gaps = 58/308 (18%)
Query: 220 DCNRCSCVHGEITCR-PVECDRAECKNPVL--HPGECCPTCLRQCLLW-GNLYEHGERFA 275
+C R +C +G TCR + C + + H +C + +C GNL +G+
Sbjct: 1894 ECERDACGNG--TCRNTIGSFNCRCNHGFILSHNNDCID--VDECASGNGNLCRNGQCIN 1949
Query: 276 PKECAECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCP-GV---- 324
+C C++G C ++ L PR C P ++ G CP G
Sbjct: 1950 TVGSFQCQCNEGYEVAPDGRTCVDINECLLEPR-KCAPGTCQNLDGSYRCICPPGYSLQN 2008
Query: 325 DYCNMGHSCDEN------ATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
+ C C E TC N + C C +GF G CQD+ G
Sbjct: 2009 EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGG 2068
Query: 377 HC-------HSNTRCVNVVGG-------------------YVCQCLGGYTRKDKFNCVEV 410
C HS C + G +C G + V++
Sbjct: 2069 KCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDM 2128
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNI 470
DEC+ H C NT GSY C C GY G C+ DEC+ G + C + C N+
Sbjct: 2129 DECKEPDVCKHGQ--CINTDGSYRCECPFGYTLAGNECVDTDECSVG-NPCGNGT-CKNV 2184
Query: 471 DGGFRCEC 478
GGF C C
Sbjct: 2185 IGGFECTC 2192
Score = 54.8 bits (126), Expect = 9e-07
Identities = 33/90 (36%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHC 378
C + C H C A+C N Y C C GFQ + + CQD++EC A + C
Sbjct: 2605 CVDENECLSAHICG-GASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGC 2663
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
SNT GGY+C C GY R + +CV
Sbjct: 2664 -SNTE-----GGYLCGCPPGYFRIGQGHCV 2687
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/225 (25%), Positives = 79/225 (35%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP-GECCKFCPG--VDYC 327
G R+ C G QC +C C P + P G+ C + +C
Sbjct: 60 GSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 119
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
N+ C +C + + C C +G+ G Q V C E+G L+G C + RC
Sbjct: 120 NI--RCMNGGSCSDDH----CLCQKGYIGTHCG-QPV--C-ESGCLNGGRCVAPNRCACT 169
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG--CHADAVCTNT--PGSYTCR------- 436
G QC Y F + C+G G C C + C
Sbjct: 170 YGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKQLCCATVGRAWGHPCEMCPAQPH 229
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + T C VDEC C C+N G F C+C
Sbjct: 230 PCRRGFIPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKC 273
Score = 43.2 bits (97), Expect = 0.003
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ CRC GY D C V+EC E C
Sbjct: 1606 DIDECQELPGLCQGGK-CINTFGSFQCRCPTGYYLNEDTRVCDDVNEC-ETPGIC-GPGT 1662
Query: 467 CVNIDGGFRCEC 478
C N G + C C
Sbjct: 1663 CYNTVGNYTCIC 1674
Score = 43.2 bits (97), Expect = 0.003
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 9/90 (10%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ D C DV+EC+ G C
Sbjct: 1607 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG-----ICGPG 1661
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N VG Y C C Y + NC+++
Sbjct: 1662 T-CYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
Score = 41.9 bits (94), Expect = 0.007
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHV 451
C GY+R C ++DECE C + +C NT GS+ C+C G + G C+ +
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGVCK-NGLCVNTRGSFKCQCPSGMTLDATGRICLDI 953
Score = 39.5 bits (88), Expect = 0.037
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 350 CNQGFQG-DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
C +G+ G C+D+DEC+ G+ C N CVN G + CQC G T
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGV----C-KNGLCVNTRGSFKCQCPSGMT 942
Score = 33.9 bits (74), Expect = 1.8
Identities = 35/162 (21%), Positives = 55/162 (33%), Gaps = 13/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C +C + C+N Y C C F+ + VD +C+
Sbjct: 1485 CTDVNECLDPTTCI-SGNCVNTPGSYICDCPPDFELNPTRVGCVDT-------RSGNCYL 1536
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
+ R G C G C + + G C + C +G
Sbjct: 1537 DIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTP--CEMCPAVNTSEYKILCPGGEG 1594
Query: 441 YEGDGYTCM--HVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ + T + +DEC E C +C+N G F+C C T
Sbjct: 1595 FRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCRCPT 1635
>AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein.
Length = 2871
Score = 146 bits (353), Expect = 3e-34
Identities = 78/219 (35%), Positives = 110/219 (50%), Gaps = 28/219 (12%)
Query: 281 ECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE--C-C----------KFC 321
EC C G CT +D P + CD Q ++PGE C C K C
Sbjct: 1220 ECSCQPGFALMPDQRSCTDIDECEDNPNI-CDGGQCTNIPGEYRCLCYDGFMASEDMKTC 1278
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-GLT-CQDVDECQEAGGLHGHHCH 379
V+ C++ + + TC N + C C+ G+ G G T C D++EC+ + H+C
Sbjct: 1279 VDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECE----IGAHNCG 1334
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N G + C C G+ D C ++DEC TH C A C NT GSY C C++
Sbjct: 1335 KHAVCTNTAGSFKCSCSPGWIG-DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKE 1393
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY GDG+TC +DEC+E + C + +C+N GG+RCEC
Sbjct: 1394 GYTGDGFTCTDLDECSENLNLC-GNGQCLNAPGGYRCEC 1431
Score = 142 bits (343), Expect = 5e-33
Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 21/266 (7%)
Query: 223 RCSCVHG-EITCRPVEC-DRAECK-NPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPK 277
RC C G +++ C D EC+ + L P C + QC + +R
Sbjct: 1137 RCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Query: 278 ECAECVCHDGNMQ--CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
+ EC +G + CT + C C P +P + + C +D C + +
Sbjct: 1197 DIDECSIMNGGCETFCTNSEGSYECS---CQPGFAL-MPDQ--RSCTDIDECEDNPNICD 1250
Query: 336 NATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N+ +Y C C GF D TC DV+EC L+ + C S T C N G ++C
Sbjct: 1251 GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECD----LNPNICLSGT-CENTKGSFIC 1305
Query: 394 QCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C GY+ +K K C +++ECE H C AVCTNT GS+ C C G+ GDG C +D
Sbjct: 1306 HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLD 1365
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC+ G+H C A C N G +RC C
Sbjct: 1366 ECSNGTHMCSQHADCKNTMGSYRCLC 1391
Score = 129 bits (311), Expect = 3e-29
Identities = 64/163 (39%), Positives = 91/163 (55%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHH 377
C ++ CN C N C N Y C C +G+ Q DG +C+D+DEC H+
Sbjct: 2442 CVDLNECNQAPKPC--NFICKNTEGSYQCSCPKGYILQEDGRSCKDLDEC----ATKQHN 2495
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C CVN +GG+ C+C G+T+ +C++ +EC + + C + +C NTPGS+TC C
Sbjct: 2496 CQF--LCVNTIGGFTCKCPPGFTQHHT-SCIDNNECTSDINLCGSKGICQNTPGSFTCEC 2552
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G+ D G +C VDEC EG+H C H C NI GG+RC C
Sbjct: 2553 QRGFSLDQTGSSCEDVDEC-EGNHRCQHG--CQNIIGGYRCSC 2592
Score = 120 bits (289), Expect = 2e-26
Identities = 63/162 (38%), Positives = 83/162 (51%), Gaps = 13/162 (8%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C+ G H C ++A C N Y C C +G+ GDG TC D+DEC E L G
Sbjct: 1361 CTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCG---- 1416
Query: 380 SNTRCVNVVGGYVCQC-LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N +C+N GGY C+C +G D C ++DEC + C N PG + C C
Sbjct: 1417 -NGQCLNAPGGYRCECDMGFVPSADGKACEDIDEC--SLPNICVFGTCHNLPGLFRCECE 1473
Query: 439 DGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE D G C V+EC + + TC S CVN G + C+C
Sbjct: 1474 IGYELDRSGGNCTDVNECLDPT-TC-ISGNCVNTPGSYICDC 1513
Score = 115 bits (277), Expect = 5e-25
Identities = 78/247 (31%), Positives = 109/247 (44%), Gaps = 34/247 (13%)
Query: 258 LRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCTRVDPELACPRLPCDPPQQF 311
+ +C + +L HG+ +C C G CT +D P L C Q
Sbjct: 1029 INECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL-CGRGQCV 1087
Query: 312 SVPG--EC-C-----------KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-- 355
+ PG EC C K C +D C C N Y C+C G Q
Sbjct: 1088 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1147
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECE 414
+ C D++EC+ L H C N RCVN++G Y C C GY + D+ CV++DEC
Sbjct: 1148 PNISACIDINECE----LSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS 1202
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDG 472
GC + CTN+ GSY C C+ G+ D +C +DEC + + C +C NI G
Sbjct: 1203 IMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIPG 1259
Query: 473 GFRCECF 479
+RC C+
Sbjct: 1260 EYRCLCY 1266
Score = 115 bits (277), Expect = 5e-25
Identities = 55/161 (34%), Positives = 83/161 (51%), Gaps = 11/161 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCH 379
C +D C G C NA C+N Y C C G++ C D +ECQE + C
Sbjct: 1806 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNI----C- 1860
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ +C++ VG + C C G+ T D+ C++++ECE + G + C NT GS+ CRC
Sbjct: 1861 SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACG---NGTCRNTIGSFNCRCN 1917
Query: 439 DGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ C+ VDEC G+ + +C+N G F+C+C
Sbjct: 1918 HGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 1958
Score = 111 bits (266), Expect = 1e-23
Identities = 66/184 (35%), Positives = 94/184 (51%), Gaps = 22/184 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT- 360
R C+ Q + GEC VD C + C C+N YTC+C G+Q LT
Sbjct: 473 RCECNKGFQLDLRGECID----VDECEK-NPC-AGGECINNQGSYTCQCRAGYQST-LTR 525
Query: 361 --CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNT 417
C+D+DEC + G + C+ N RC+N G + C C G+ +D NC ++DEC +
Sbjct: 526 TECRDIDECLQNGRI----CN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC--SI 578
Query: 418 HGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
+ +C N GS+ C C+ G++ DG C ++EC E C + RCVN DG +R
Sbjct: 579 RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNG-RCVNTDGSYR 636
Query: 476 CECF 479
CECF
Sbjct: 637 CECF 640
Score = 108 bits (259), Expect = 7e-23
Identities = 64/170 (37%), Positives = 80/170 (47%), Gaps = 11/170 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF-QGDGLTCQDVDECQEAGGLHGHHCH 379
C ++ C +C N TC N + C+CN GF C DVDEC A G +G+ C
Sbjct: 1889 CLDINECERD-ACG-NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDEC--ASG-NGNLCR 1943
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N +C+N VG + CQC GY D CV+++EC C A C N GSY C C
Sbjct: 1944 -NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC-APGTCQNLDGSYRCICP 2001
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
GY C +DEC E C C N +G F+C C E LS S
Sbjct: 2002 PGYSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLC-PEGFSLSSS 2049
Score = 107 bits (256), Expect = 2e-22
Identities = 54/158 (34%), Positives = 75/158 (47%), Gaps = 11/158 (6%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
+D C + H N C+N Y C C G+ D G +C D++EC +A C N
Sbjct: 2403 IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAP----KPC--N 2456
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C GY ++D +C ++DEC H C +C NT G +TC+C G
Sbjct: 2457 FICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF--LCVNTIGGFTCKCPPG 2514
Query: 441 YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +C+ +ECT + C C N G F CEC
Sbjct: 2515 FTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCEC 2552
Score = 103 bits (248), Expect = 2e-21
Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 31/211 (14%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGEC-----CKFCPGVDYCNMGHS 332
EC N +C C C P +F+ G+C C+ P + C+ G
Sbjct: 1811 ECQNGPVCQRNAECINTAGSYRCD---CKPGYRFTSTGQCNDRNECQEIPNI--CSHGQ- 1864
Query: 333 CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C++ + C C+ GF+ D C D++EC+ C + T C N +G
Sbjct: 1865 ------CIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDA------CGNGT-CRNTIGS 1911
Query: 391 YVCQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYT 447
+ C+C G+ +C++VDEC GN + C + C NT GS+ C+C +GYE DG T
Sbjct: 1912 FNCRCNHGFILSHNNDCIDVDECASGNGNLCR-NGQCINTVGSFQCQCNEGYEVAPDGRT 1970
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+ ++EC C C N+DG +RC C
Sbjct: 1971 CVDINECLLEPRKC-APGTCQNLDGSYRCIC 2000
Score = 103 bits (247), Expect = 2e-21
Identities = 68/214 (31%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG 330
G + +EC EC M+ T EL CPR P ++ + G+ F ++ C M
Sbjct: 985 GAAWGTEECEECP-----MRNTPEYEEL-CPRGPGFATKEIT-NGK--PFFKDINECKMI 1035
Query: 331 HSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
S + C N + C+C+ GF D C D+DEC+ + L G +CVN
Sbjct: 1036 PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCG-----RGQCVNTP 1090
Query: 389 GGYVCQCLGGYTRKDKF--NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GD 444
G + C+C GY NC+++DEC+ + C VC NT GSY C C G++ +
Sbjct: 1091 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPN 1149
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+ ++EC +H C + RCVN+ G ++C C
Sbjct: 1150 ISACIDINECELSAHLC-PNGRCVNLIGKYQCAC 1182
Score = 102 bits (245), Expect = 3e-21
Identities = 53/151 (35%), Positives = 78/151 (51%), Gaps = 16/151 (10%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C C N +TC+C +GF D G +C+DVDEC+ H C C N++GG
Sbjct: 2535 CGSKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECEG-----NHRCQHG--CQNIIGG 2587
Query: 391 YVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-- 447
Y C C GY + ++N CV+ +EC + H C A C NT GSY C C G++ + ++
Sbjct: 2588 YRCSCPQGYLQHYQWNQCVDENECL-SAHIC-GGASCHNTLGSYKCMCPAGFQYEQFSGG 2645
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C ++EC C + + N +GG+ C C
Sbjct: 2646 CQDINECGSAQAPCSYGSS--NTEGGYLCGC 2674
Score = 100 bits (240), Expect = 1e-20
Identities = 63/186 (33%), Positives = 92/186 (49%), Gaps = 18/186 (9%)
Query: 301 PRLPCD-PPQQFSVPG-ECCKFCPG--VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG 356
P++P PP ++ P E + P DYC + +N C+ C+CN+GFQ
Sbjct: 423 PQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQL 482
Query: 357 D-GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECE 414
D C DVDEC++ + C + C+N G Y CQC GY + + C ++DEC
Sbjct: 483 DLRGECIDVDECEK------NPC-AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECL 535
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDG 472
N C+ + C NT GS+ C C G+ DG C +DEC+ + C + C+N DG
Sbjct: 536 QNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI-RNMC-LNGMCINEDG 592
Query: 473 GFRCEC 478
F+C C
Sbjct: 593 SFKCIC 598
Score = 99 bits (238), Expect = 2e-20
Identities = 55/158 (34%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C C ++ C+N + Y C+C G+ G C D DEC G+ C + T
Sbjct: 2128 MDECKEPDVC-KHGQCINTDGSYRCECPFGYILAGNECVDTDECSV-----GNPCGNGT- 2180
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY-- 441
C NV+GG+ C C G+ C +++EC N C C NT GSY C+C GY
Sbjct: 2181 CKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTYGSYECKCPVGYVL 2238
Query: 442 EGDGYTCMHVDECTEGSHTC-HHSARCVNIDGGFRCEC 478
D C DEC EG H C C N+ G + C C
Sbjct: 2239 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCIC 2276
Score = 93.9 bits (223), Expect = 2e-18
Identities = 50/159 (31%), Positives = 73/159 (45%), Gaps = 13/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSN 381
+D C EN C+N+ + C+C GF L C+D+DECQ +G C N
Sbjct: 1767 IDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-----NGPVCQRN 1821
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N G Y C C GY C + +EC+ + C + C +T GS+ C C G+
Sbjct: 1822 AECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGF 1880
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ D C+ ++EC + C + C N G F C C
Sbjct: 1881 KTNDDQTMCLDINECERDA--CGNGT-CRNTIGSFNCRC 1916
Score = 87.0 bits (206), Expect = 2e-16
Identities = 45/120 (37%), Positives = 64/120 (53%), Gaps = 9/120 (7%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCH 421
D+DEC+E G+ C + C+N+VG + C+C G+ DK C ++DEC+ N C
Sbjct: 1766 DIDECREIPGV----CENGV-CINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQ 1819
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+A C NT GSY C C+ GY C +EC E + C H +C++ G F C C T
Sbjct: 1820 RNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSH-GQCIDTVGSFYCLCHT 1878
Score = 81.8 bits (193), Expect = 7e-15
Identities = 59/170 (34%), Positives = 78/170 (45%), Gaps = 18/170 (10%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHG 375
ECC C +Y G C + N + +Y C+ G G D++EC L
Sbjct: 682 ECC--CASTEYA-FGEPC-QPCPAQN-SAEYQALCSSG-PGMTSAGSDINEC----ALDP 731
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
C N C N+ G Y C C GY NCV+++EC N+ C + C NTPGS+
Sbjct: 732 DIC-PNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCD-NGQCRNTPGSFV 789
Query: 435 CRCRDG--YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTEN 482
C C G Y+ D TC +DEC S C + C N G F CEC +E+
Sbjct: 790 CTCPKGFIYKPDLKTCEDIDECE--SSPCINGV-CKNSPGSFICECSSES 836
Score = 79.8 bits (188), Expect = 3e-14
Identities = 62/207 (29%), Positives = 83/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPT---CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT C +C L GE EC + C G +C C C
Sbjct: 463 GRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGG--ECINNQGSYTCQ---CRA 517
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q ++ C+ +D C N C+N + + C CN GF DG C+D+D
Sbjct: 518 GYQSTLTRTECR---DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMD 574
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ D C +++ECE T G +
Sbjct: 575 ECSIR-----NMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE--TPGICMNG 626
Query: 425 VCTNTPGSYTCRCRDGYEG--DGYTCM 449
C NT GSY C C G DG C+
Sbjct: 627 RCVNTDGSYRCECFPGLAVGLDGRVCV 653
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/146 (34%), Positives = 69/146 (47%), Gaps = 20/146 (13%)
Query: 304 PCDP-PQQFSVPGEC-CKFCPG-------VDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
PC P P Q S + C PG ++ C + N C NL Y C CN G+
Sbjct: 695 PCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGY 754
Query: 355 QGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVD 411
+ D G C D++EC L+ C N +C N G +VC C G+ K D C ++D
Sbjct: 755 EVDSTGKNCVDINECV----LNSLLC-DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID 809
Query: 412 ECEGNTHGCHADAVCTNTPGSYTCRC 437
ECE + C + VC N+PGS+ C C
Sbjct: 810 ECESSP--C-INGVCKNSPGSFICEC 832
Score = 74.9 bits (176), Expect = 8e-13
Identities = 44/125 (35%), Positives = 60/125 (48%), Gaps = 11/125 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C+ + N C+N Y C+C+ GF DG C+D+DEC + C
Sbjct: 1402 CTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLP-----NIC 1456
Query: 379 HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
T C N+ G + C+C GY + NC +V+EC T C C NTPGSY C C
Sbjct: 1457 VFGT-CHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPT-TC-ISGNCVNTPGSYICDC 1513
Query: 438 RDGYE 442
+E
Sbjct: 1514 PPDFE 1518
Score = 70.1 bits (164), Expect = 2e-11
Identities = 74/259 (28%), Positives = 94/259 (36%), Gaps = 32/259 (12%)
Query: 221 CNRCSCVHGEITC-RPVECDRAECKNPVLHPGECC--PTCLRQCLLWGNLYEHGERFAPK 277
C S H I C C C + G C P C CL G AP
Sbjct: 111 CGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCL------NGGRCVAPN 164
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK--FCPGVDYCNMGHSCDE 335
CA C QC R C + + Q + G C C GH C+
Sbjct: 165 RCA-CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCE- 222
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
+ C +GF + T CQDVDECQ GL C C+N VG + C
Sbjct: 223 ------MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGL----CQGGN-CINTVGSFEC 271
Query: 394 QCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMH 450
+C G+ + C ++DEC C CTNT SY C+C G+ DG C
Sbjct: 272 KCPAGHKLNEVSQKCEDIDECSTIPGICEGGE-CTNTVSSYFCKCPPGFYTSPDGTRC-- 328
Query: 451 VDECTEGSHTCHHSARCVN 469
+D +T + RC N
Sbjct: 329 IDVRPGYCYTALTNGRCSN 347
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/119 (36%), Positives = 59/119 (49%), Gaps = 15/119 (12%)
Query: 339 CMNLNT---KYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C +NT K C +GF+ + +T +D+DECQE GL C +C+N G + C
Sbjct: 1577 CPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL----CQGG-KCINTFGSFQC 1631
Query: 394 QC-LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCM 449
+C G Y +D C +V+ECE T G C NT G+YTC C Y G CM
Sbjct: 1632 RCPTGYYLNEDTRVCDDVNECE--TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM 1688
Score = 67.7 bits (158), Expect = 1e-10
Identities = 76/291 (26%), Positives = 109/291 (37%), Gaps = 46/291 (15%)
Query: 224 CSCVHGEITCRPVEC-DRAEC-KNPVLHPGECCPTC-LRQCLLWGNLYEHGERFAPKECA 280
C+C G + C D EC +NP+L C T +C +R K+
Sbjct: 2190 CTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKD-- 2247
Query: 281 ECVCHDGNMQCTRVDPELACPRLP------CDPPQQFSVPGECCKFCPGVDYCNMGHSCD 334
E C +G CT + ++ C L C P Q GE C + C
Sbjct: 2248 EDECEEGKHDCT--EKQMECKNLIGTYMCICGPGYQRRPDGEGCV---DENECQTKPGIC 2302
Query: 335 ENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
EN C+N YTC+CN GF + C D E + + C + N V
Sbjct: 2303 ENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSE 2362
Query: 393 CQCLGG-----------------------YTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
C C GG + R N ++DEC+ H + C N
Sbjct: 2363 CCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECK-VIHDVCRNGECVND 2421
Query: 430 PGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GSY C C+ GY D G +C+ ++EC + C+ C N +G ++C C
Sbjct: 2422 RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFI--CKNTEGSYQCSC 2470
Score = 66.9 bits (156), Expect = 2e-10
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 33/185 (17%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
K C ++ C + +N C N + C C +GF + D TC+D+DEC+ + ++G
Sbjct: 761 KNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGV 820
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVE----------VD-ECEGNTHGCHADA 424
C N G ++C+C T K C+E +D CE N +G +
Sbjct: 821 -------CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKS 873
Query: 425 VCTNTPGSY------TCR----CRDGYEG-DGYTCMHVDECTEGSHTCHHSARCVNIDGG 473
C ++ G+ C+ C GY G C +DEC C + CVN G
Sbjct: 874 QCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGL-CVNTRGS 932
Query: 474 FRCEC 478
F+C+C
Sbjct: 933 FKCQC 937
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/141 (30%), Positives = 61/141 (43%), Gaps = 16/141 (11%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQ 362
C+ + FS+ + C VD C H C C N+ Y C C QG+ C
Sbjct: 2550 CECQRGFSLD-QTGSSCEDVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCV 2606
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGC 420
D +EC A G CH N +G Y C C G+ + ++F+ C +++EC C
Sbjct: 2607 DENECLSAHICGGASCH------NTLGSYKCMCPAGF-QYEQFSGGCQDINECGSAQAPC 2659
Query: 421 HADAVCTNTPGSYTCRCRDGY 441
+ +NT G Y C C GY
Sbjct: 2660 SYGS--SNTEGGYLCGCPPGY 2678
Score = 65.7 bits (153), Expect = 5e-10
Identities = 79/308 (25%), Positives = 112/308 (36%), Gaps = 58/308 (18%)
Query: 220 DCNRCSCVHGEITCR-PVECDRAECKNPVL--HPGECCPTCLRQCLLW-GNLYEHGERFA 275
+C R +C +G TCR + C + + H +C + +C GNL +G+
Sbjct: 1894 ECERDACGNG--TCRNTIGSFNCRCNHGFILSHNNDCID--VDECASGNGNLCRNGQCIN 1949
Query: 276 PKECAECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCP-GV---- 324
+C C++G C ++ L PR C P ++ G CP G
Sbjct: 1950 TVGSFQCQCNEGYEVAPDGRTCVDINECLLEPR-KCAPGTCQNLDGSYRCICPPGYSLQN 2008
Query: 325 DYCNMGHSCDEN------ATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
+ C C E TC N + C C +GF G CQD+ G
Sbjct: 2009 EKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGG 2068
Query: 377 HC-------HSNTRCVNVVGG-------------------YVCQCLGGYTRKDKFNCVEV 410
C HS C + G +C G + V++
Sbjct: 2069 KCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDM 2128
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNI 470
DEC+ H C NT GSY C C GY G C+ DEC+ G + C + C N+
Sbjct: 2129 DECKEPDVCKHGQ--CINTDGSYRCECPFGYILAGNECVDTDECSVG-NPCGNGT-CKNV 2184
Query: 471 DGGFRCEC 478
GGF C C
Sbjct: 2185 IGGFECTC 2192
Score = 50.8 bits (116), Expect = 1e-05
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 9/90 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHC 378
C + C H C A+C N Y C C GFQ + + CQD++EC A +
Sbjct: 2605 CVDENECLSAHICG-GASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYGS 2663
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
SNT GGY+C C GY R + +CV
Sbjct: 2664 -SNTE-----GGYLCGCPPGYFRIGQGHCV 2687
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/225 (25%), Positives = 81/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP-GECCKFCPG--VDYC 327
G R+ C G QC +C C P + P G+ C + +C
Sbjct: 60 GSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 119
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
N+ C +C + + C C +G+ G Q V C E+G L+G C + RC
Sbjct: 120 NI--RCMNGGSCSDDH----CLCQKGYIGTHCG-QPV--C-ESGCLNGGRCVAPNRCACT 169
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG-CHADAVCTNTPG---SYTCR------- 436
G QC Y F + C+G G +C T G + C
Sbjct: 170 YGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH 229
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + T C VDEC C C+N G F C+C
Sbjct: 230 PCRRGFIPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKC 273
Score = 43.2 bits (97), Expect = 0.003
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ CRC GY D C V+EC E C
Sbjct: 1606 DIDECQELPGLCQGGK-CINTFGSFQCRCPTGYYLNEDTRVCDDVNEC-ETPGIC-GPGT 1662
Query: 467 CVNIDGGFRCEC 478
C N G + C C
Sbjct: 1663 CYNTVGNYTCIC 1674
Score = 43.2 bits (97), Expect = 0.003
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 9/90 (10%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ D C DV+EC+ G C
Sbjct: 1607 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG-----ICGPG 1661
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N VG Y C C Y + NC+++
Sbjct: 1662 T-CYNTVGNYTCICPPDYMQVNGGNNCMDM 1690
Score = 41.9 bits (94), Expect = 0.007
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHV 451
C GY+R C ++DECE C + +C NT GS+ C+C G + G C+ +
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGVCK-NGLCVNTRGSFKCQCPSGMTLDATGRICLDI 953
Score = 39.5 bits (88), Expect = 0.037
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 350 CNQGFQG-DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
C +G+ G C+D+DEC+ G+ C N CVN G + CQC G T
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGV----C-KNGLCVNTRGSFKCQCPSGMT 942
Score = 33.9 bits (74), Expect = 1.8
Identities = 35/162 (21%), Positives = 55/162 (33%), Gaps = 13/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C +C + C+N Y C C F+ + VD +C+
Sbjct: 1485 CTDVNECLDPTTCI-SGNCVNTPGSYICDCPPDFELNPTRVGCVDT-------RSGNCYL 1536
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
+ R G C G C + + G C + C +G
Sbjct: 1537 DIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTP--CEMCPAVNTSEYKILCPGGEG 1594
Query: 441 YEGDGYTCM--HVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ + T + +DEC E C +C+N G F+C C T
Sbjct: 1595 FRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCRCPT 1635
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 143 bits (347), Expect = 2e-33
Identities = 76/219 (34%), Positives = 108/219 (49%), Gaps = 28/219 (12%)
Query: 281 ECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE--C-C----------KFC 321
EC C +G C +D P + CD Q ++PGE C C K C
Sbjct: 1264 ECSCSEGYALMPDGRSCADIDECENNPDI-CDGGQCTNIPGEYRCLCYDGFMASMDMKTC 1322
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHCH 379
V+ C++ + C N + C C G+ G T C DVDEC+ + H+C
Sbjct: 1323 IDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECE----IGAHNCD 1378
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C+N+ G + C C G+ C+++DEC TH C +A C NTPGSY C C +
Sbjct: 1379 MHASCLNIPGSFKCSCREGWIGNG-IKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSE 1437
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+TC VDEC E + C + +C+N+ G +RCEC
Sbjct: 1438 GFTGDGFTCSDVDECAENINLC-ENGQCLNVPGAYRCEC 1475
Score = 142 bits (344), Expect = 3e-33
Identities = 90/303 (29%), Positives = 133/303 (43%), Gaps = 22/303 (7%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C N + G + + +C C G E++ +C D EC
Sbjct: 1144 GYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINEC 1203
Query: 244 K--NPVLHPGECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPEL 298
+ + G+C QC +R + EC+ +G + QCT +
Sbjct: 1204 SLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSY 1263
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-- 356
C C G + C +D C + C N+ +Y C C GF
Sbjct: 1264 ECS---CSEGYALMPDG---RSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASM 1317
Query: 357 DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEG 415
D TC DV+EC L+ + C C N G ++C C GY+ +K C +VDECE
Sbjct: 1318 DMKTCIDVNECD----LNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI 1372
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
H C A C N PGS+ C CR+G+ G+G C+ +DEC+ G+H C +A+CVN G +R
Sbjct: 1373 GAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYR 1432
Query: 476 CEC 478
C C
Sbjct: 1433 CAC 1435
Score = 127 bits (307), Expect = 1e-28
Identities = 65/162 (40%), Positives = 84/162 (51%), Gaps = 13/162 (8%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C+ G H C NA C+N Y C C++GF GDG TC DVDEC E L C
Sbjct: 1405 CIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINL----CE 1460
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N +C+NV G Y C+C G+T D +C ++DEC + C N PG + C C
Sbjct: 1461 -NGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC--SFQNICVSGTCNNLPGMFHCICD 1517
Query: 439 DGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
DGYE D G C +DEC + + + CVN G + C C
Sbjct: 1518 DGYELDRTGGNCTDIDECADPINCV--NGLCVNTPGRYECNC 1557
Score = 123 bits (297), Expect = 2e-27
Identities = 64/163 (39%), Positives = 87/163 (53%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHH 377
C +D C+ C N C N Y C C +G+ Q DG TC+D+DECQ H+
Sbjct: 2488 CIDLDECSQSPKPC--NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQ----HN 2541
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C CVN +GG+ C+C G+T+ C++ +EC C +C NTPGS++C C
Sbjct: 2542 CQF--LCVNTLGGFTCKCPPGFTQHHTA-CIDNNECGSQPLLCGGKGICQNTPGSFSCEC 2598
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G+ D G C VDEC +G+H C H C NI GG+RC C
Sbjct: 2599 QRGFSLDATGLNCEDVDEC-DGNHRCQHG--CQNILGGYRCGC 2638
Score = 111 bits (266), Expect = 1e-23
Identities = 58/166 (34%), Positives = 78/166 (46%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C +D C TC+N + C C G + C D++EC + L
Sbjct: 1153 KNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNL--- 1209
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C N +CVN++G Y C C GY D+ C ++DEC GC D CTN+ GSY C
Sbjct: 1210 -CR-NGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGC--DTQCTNSEGSYEC 1265
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +GY DG +C +DEC C +C NI G +RC C+
Sbjct: 1266 SCSEGYALMPDGRSCADIDECENNPDICD-GGQCTNIPGEYRCLCY 1310
Score = 109 bits (261), Expect = 4e-23
Identities = 56/151 (37%), Positives = 79/151 (52%), Gaps = 16/151 (10%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C C N ++C+C +GF D GL C+DVDEC H C C N++GG
Sbjct: 2581 CGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG-----NHRCQHG--CQNILGG 2633
Query: 391 YVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-- 447
Y C C GY + ++N CV+ +EC N + C A C NT GSY C C G+ D ++
Sbjct: 2634 YRCGCPQGYIQHYQWNQCVDENECS-NPNAC-GSASCYNTLGSYKCACPSGFSFDQFSSA 2691
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C V+EC+ + C++ C N +GG+ C C
Sbjct: 2692 CHDVNECSSSKNPCNYG--CSNTEGGYLCGC 2720
Score = 107 bits (257), Expect = 1e-22
Identities = 58/160 (36%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C N TC N Y C C GF+ C D+DEC G C
Sbjct: 1931 CMDVDECER-HPCG-NGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSS---FFGQVCR 1985
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N RC N +G + C C GY D NC++ +EC C + C N GS+ C C
Sbjct: 1986 -NGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSC-SPGTCQNLEGSFRCICP 2043
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE C+ ++EC E + C + C N GGF+C C
Sbjct: 2044 PGYEVKSENCIDINECDEDPNICLFGS-CTNTPGGFQCLC 2082
Score = 101 bits (243), Expect = 6e-21
Identities = 70/203 (34%), Positives = 97/203 (47%), Gaps = 22/203 (10%)
Query: 283 VC-HDGNMQCT-RVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCM 340
+C H N+ R P ++ R C+ + G+C VD C + C N C+
Sbjct: 496 ICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCID----VDECT-SNPCT-NGDCV 549
Query: 341 NLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
N Y CKC+ GFQ C D+DEC + G L C N RCVN G + C C G
Sbjct: 550 NTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVL----C-KNGRCVNSDGSFQCICNAG 604
Query: 399 YT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECT 455
+ D NCV+ DEC T+ C + +C N GS+ C C+ G+ +G C VDEC
Sbjct: 605 FELTTDGKNCVDHDECT-TTNMC-LNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDEC- 661
Query: 456 EGSHTCHHSARCVNIDGGFRCEC 478
+ C + C+N +G FRC+C
Sbjct: 662 QTPGICMNG-HCINSEGSFRCDC 683
Score = 101 bits (242), Expect = 8e-21
Identities = 57/159 (35%), Positives = 81/159 (50%), Gaps = 14/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNT 382
+D C + N C+ + Y C+CN G++ D C DVDEC + C +N
Sbjct: 494 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECT------SNPC-TNG 546
Query: 383 RCVNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN G Y C+C G+ R K C+++DEC N C + C N+ GS+ C C G+
Sbjct: 547 DCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLC-KNGRCVNSDGSFQCICNAGF 605
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E DG C+ DECT ++ C + C+N DG F+C C
Sbjct: 606 ELTTDGKNCVDHDECTT-TNMC-LNGMCINEDGSFKCIC 642
Score = 101 bits (242), Expect = 8e-21
Identities = 56/160 (35%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC G+ C +
Sbjct: 2171 VNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI-----GNPCGNG 2225
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+G + C C G+ NC +++EC N C C NT GSY C C GY
Sbjct: 2226 T-CTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCALR--CMNTFGSYECTCPIGY 2282
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
D C +DEC EG H C C N+ G F C C
Sbjct: 2283 ALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 2322
Score = 98.7 bits (235), Expect = 6e-20
Identities = 51/158 (32%), Positives = 72/158 (45%), Gaps = 11/158 (6%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
+D C + + N C+N + C C G+ D G +C D+DEC ++ C N
Sbjct: 2449 IDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP----KPC--N 2502
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C GY ++D C ++DEC+ H C +C NT G +TC+C G
Sbjct: 2503 YICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCKCPPG 2560
Query: 441 YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C+ +EC C C N G F CEC
Sbjct: 2561 FTQHHTACIDNNECGSQPLLCGGKGICQNTPGSFSCEC 2598
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/160 (31%), Positives = 73/160 (45%), Gaps = 12/160 (7%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSN 381
+D C N C+N + C+C GF + L C+D+DEC L C N
Sbjct: 1808 IDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNL----CQRN 1863
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N G Y C+C G+ CV+ +EC + C + +C + GSY C C +G+
Sbjct: 1864 ADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC-SHGLCVDLQGSYQCICHNGF 1922
Query: 442 EG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ D CM VDEC H C + C N G + C C+
Sbjct: 1923 KASQDQTMCMDVDECER--HPCGNGT-CKNTVGSYNCLCY 1959
Score = 94.3 bits (224), Expect = 1e-18
Identities = 83/283 (29%), Positives = 122/283 (43%), Gaps = 40/283 (14%)
Query: 214 GATWQRDCNRC----SCVHGEITCRPVEC-DRAECKNPVLHPGECCPTCLRQCL-LWGNL 267
GA W C RC +C G + V C D EC+ + PG CP +C+ G+
Sbjct: 924 GAAWGSPCERCELDTACPRGLARIKGVTCEDVNECE---VFPG-VCPN--GRCVNSKGSF 977
Query: 268 YEHGERFAPKECAECVCHDGNM-QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDY 326
+ + VC D M QC E C P +F + CC G +
Sbjct: 978 HCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIH---PVPGKFRMDACCCAV--GAAW 1032
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLT----CQDVDECQEAGGLHGHHCHS 380
G C+E + C GF +GD LT +D++EC+ G+ C +
Sbjct: 1033 ---GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGM----C-T 1084
Query: 381 NTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+C N +G + C+C G+ ++ NC ++DEC + C +C NTPGS+ C C +
Sbjct: 1085 YGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLC-GSGICVNTPGSFECECFE 1143
Query: 440 GYEGDGY----TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE G+ CM +D C C CVN +G F+C+C
Sbjct: 1144 GYE-SGFMMMKNCMDIDGCERNPLLC-RGGTCVNTEGSFQCDC 1184
Score = 91.9 bits (218), Expect = 6e-18
Identities = 55/179 (30%), Positives = 86/179 (48%), Gaps = 13/179 (7%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQGDGLTCQ- 362
C+ F+V C C + G+ C+ T + K C GF D T +
Sbjct: 1748 CENELPFNVTKRMC--CCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKA 1805
Query: 363 -DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGC 420
D+DEC+E G+ C +N C+N +G + C+C G++ D C ++DEC + C
Sbjct: 1806 VDIDECKEIPGI----C-ANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLC 1860
Query: 421 HADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+A C N+PGSY C C G++ C+ +EC E + C H CV++ G ++C C
Sbjct: 1861 QRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQCIC 1918
Score = 90.6 bits (215), Expect = 1e-17
Identities = 48/125 (38%), Positives = 66/125 (52%), Gaps = 13/125 (10%)
Query: 358 GLTC--QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEG 415
GLT Q +D C+ H + C N RC+ V Y C+C GY + +C++VDEC
Sbjct: 486 GLTILNQTIDICKH----HANLC-LNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTS 540
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGG 473
N C + C NTPGSY C+C G++ C+ +DEC + C + RCVN DG
Sbjct: 541 NP--C-TNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLC-KNGRCVNSDGS 596
Query: 474 FRCEC 478
F+C C
Sbjct: 597 FQCIC 601
Score = 85.4 bits (202), Expect = 6e-16
Identities = 68/225 (30%), Positives = 95/225 (42%), Gaps = 35/225 (15%)
Query: 240 RAECKNPV-LHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R EC L P C +CL N+ HG + +C+CH+G C
Sbjct: 1874 RCECAAGFKLSPNGACVD-RNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCM 1932
Query: 293 RVDPELACPRLPCDPPQQFSVPGECCKFC-PG-----------VDYCN--MGHSCDENAT 338
VD C R PC + G C PG +D C+ G C N
Sbjct: 1933 DVDE---CERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVC-RNGR 1988
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C CN+G++ DG C D +EC G C T C N+ G + C C
Sbjct: 1989 CFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPG----SCSPGT-CQNLEGSFRCICP 2043
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
GY K + NC++++EC+ + + C + CTNTPG + C C G+
Sbjct: 2044 PGYEVKSE-NCIDINECDEDPNICLFGS-CTNTPGGFQCLCPPGF 2086
Score = 85.0 bits (201), Expect = 7e-16
Identities = 58/166 (34%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHG 375
ECC C DY G C + C G DG +D++EC L
Sbjct: 726 ECC--CANPDY-GFGEPCQPCPAKNSAEFHGLCSSGVGITVDG---RDINEC----ALDP 775
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPGSYT 434
C +N C N+ G Y C C GY NC+++DEC N C + +C NTPGSY+
Sbjct: 776 DIC-ANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCD-NGLCRNTPGSYS 833
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C C GY + TC ++EC S+ C + A C N G F CEC
Sbjct: 834 CTCPPGYVFRTETETCEDINECE--SNPCVNGA-CRNNLGSFNCEC 876
Score = 80.6 bits (190), Expect = 2e-14
Identities = 44/125 (35%), Positives = 61/125 (48%), Gaps = 11/125 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C VD C + EN C+N+ Y C+C GF D +CQD+DEC + C
Sbjct: 1446 CSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-----FQNIC 1500
Query: 379 HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
S T C N+ G + C C GY + NC ++DEC + C + +C NTPG Y C C
Sbjct: 1501 VSGT-CNNLPGMFHCICDDGYELDRTGGNCTDIDEC-ADPINC-VNGLCVNTPGRYECNC 1557
Query: 438 RDGYE 442
++
Sbjct: 1558 PPDFQ 1562
Score = 79.4 bits (187), Expect = 4e-14
Identities = 50/160 (31%), Positives = 68/160 (42%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ D G C D+DEC L N
Sbjct: 768 INECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDEC-----LVNRLLCDN 822
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C GY R + C +++ECE N C + C N GS+ C C G
Sbjct: 823 GLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNP--C-VNGACRNNLGSFNCECSPG 879
Query: 441 YEGDGYTCMHVDECTEGSHTCHHSARC-VNIDGG-FRCEC 478
+ + +D +RC VNI+G + EC
Sbjct: 880 SKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSEC 919
Score = 74.5 bits (175), Expect = 1e-12
Identities = 79/290 (27%), Positives = 114/290 (39%), Gaps = 44/290 (15%)
Query: 224 CSCVHGEITCRPVEC-DRAEC-KNPVLHPGECCPTC-LRQCLL-WGNLYEHGERFAPK-- 277
C+C G + C D EC +NP+L C T +C G ++
Sbjct: 2236 CNCNEGFEPGPMMNCEDINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQKMCKDLD 2295
Query: 278 ECAECV--CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE + C M C + C C P GE C + C E
Sbjct: 2296 ECAEGLHDCESRGMMCKNLIGTFMCI---CPPGMARRPDGEGCV---DENECRTKPGICE 2349
Query: 336 NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDE-----------CQEAGGLHGHHCHSNT 382
N C+N+ Y C+CN+GFQ G C D + CQ A S
Sbjct: 2350 NGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSEC 2409
Query: 383 RCVNVVG-GYVCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTP 430
C G G+ C+ C T + K C ++DEC+ + C + C NT
Sbjct: 2410 CCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLC-TNGQCINTM 2468
Query: 431 GSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GS+ C C+ GY D G +C+ +DEC++ C++ C N +G ++C C
Sbjct: 2469 GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYI--CKNTEGSYQCSC 2516
Score = 71.3 bits (167), Expect = 1e-11
Identities = 42/125 (33%), Positives = 58/125 (46%), Gaps = 15/125 (12%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C VD C+ H C C N+ Y C C QG+ C D +EC C
Sbjct: 2611 CEDVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA-----C 2663
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
S + C N +G Y C C G++ D+F+ C +V+EC + + C+ C+NT G Y C
Sbjct: 2664 GSAS-CYNTLGSYKCACPSGFSF-DQFSSACHDVNECSSSKNPCNYG--CSNTEGGYLCG 2719
Query: 437 CRDGY 441
C GY
Sbjct: 2720 CPPGY 2724
Score = 70.5 bits (165), Expect = 2e-11
Identities = 57/190 (30%), Positives = 74/190 (38%), Gaps = 29/190 (15%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGEC-CKF------------CPGV 324
EC D N C VD C PC + PG CK C +
Sbjct: 519 ECNMGYKQDANGDCIDVDE---CTSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDI 575
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C +N C+N + + C CN GF+ DG C D DEC + C N
Sbjct: 576 DECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNCVDHDECTTT-----NMC-LNG 629
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N G + C C G+ C +VDEC+ T G + C N+ GS+ C C G
Sbjct: 630 MCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ--TPGICMNGHCINSEGSFRCDCPPGL 687
Query: 442 E--GDGYTCM 449
DG C+
Sbjct: 688 AVGMDGRVCV 697
Score = 66.5 bits (155), Expect = 3e-10
Identities = 39/105 (37%), Positives = 52/105 (49%), Gaps = 11/105 (10%)
Query: 350 CNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN- 406
C +GF + T CQDVDECQ G+ C C+N VG + C+C G+ + +
Sbjct: 260 CRRGFIPNIRTGACQDVDECQAIPGI----CQGGN-CINTVGSFECRCPAGHKQSETTQK 314
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCM 449
C ++DEC C C+NT GSY C C GY DG C+
Sbjct: 315 CEDIDECSIIPGICETGE-CSNTVGSYFCVCPRGYVTSTDGSRCI 358
Score = 55.2 bits (127), Expect = 7e-07
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSAR 466
+++EC+ C C NT GS+ CRC G+ D C +DEC C S
Sbjct: 1072 DINECKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCG-SGI 1129
Query: 467 CVNIDGGFRCECF 479
CVN G F CECF
Sbjct: 1130 CVNTPGSFECECF 1142
Score = 54.0 bits (124), Expect = 2e-06
Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHC 378
C + C+ ++C +A+C N Y C C GF D + C DV+EC + + C
Sbjct: 2651 CVDENECSNPNACG-SASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK----NPC 2705
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
N C N GGY+C C GY R + +CV
Sbjct: 2706 --NYGCSNTEGGYLCGCPPGYYRVGQGHCV 2733
Score = 49.2 bits (112), Expect = 5e-05
Identities = 83/334 (24%), Positives = 113/334 (33%), Gaps = 57/334 (17%)
Query: 184 KLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDC-NRCSCVHGEITCRPV-ECDRA 241
KL A + R E + C V G+ +Q C N + C V EC+R
Sbjct: 1882 KLSPNGACVDRNECLEIPNVCSHGLCVDLQGS-YQCICHNGFKASQDQTMCMDVDECERH 1940
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAEC---VCHDGNMQCTRVDPEL 298
C N CL C L + + EC+ VC +G R E+
Sbjct: 1941 PCGNGTCKNTVGSYNCL--CYPGFELTHNNDCLDIDECSSFFGQVCRNG-----RCFNEI 1993
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
+ C+ + + G K C + C + SC TC NL + C C G++
Sbjct: 1994 GSFKCLCNEGYELTPDG---KNCIDTNECVALPGSCSPG-TCQNLEGSFRCICPPGYEVK 2049
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDE--CE 414
C D++EC E + C + C N GG+ C C G+ D C + + C
Sbjct: 2050 SENCIDINECDEDPNI----CLFGS-CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCF 2104
Query: 415 GNTHG--CHADAVCTNTPGSYTCRCRDGYEGDGYTC---------MHVDECTEGSHT--- 460
N C T C G EG G C D C G T
Sbjct: 2105 TNFENGKCSVPKAFNTTKAKCCCSKMPG-EGWGDPCELCPKDDEVAFQDLCPYGHGTVPS 2163
Query: 461 ----------CHHS------ARCVNIDGGFRCEC 478
C S +C+N DG FRCEC
Sbjct: 2164 LHDTREDVNECLESPGICSNGQCINTDGSFRCEC 2197
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/228 (28%), Positives = 86/228 (37%), Gaps = 38/228 (16%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
C+C DG CT +D E A P + C V G C PG CN
Sbjct: 1514 CICDDGYELDRTGGNCTDID-ECADP-INC-------VNGLCVN-TPGRYECNCPPDFQL 1563
Query: 336 NAT---CMNLNTKYTCKCNQGFQGDG-LTCQD-----VDE---CQEAGGLHGHHCHSNTR 383
N T C++ N C G +GDG L+C V C G G+ C +
Sbjct: 1564 NPTGVGCVD-NRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPP 1622
Query: 384 CVNVVGGYVCQCLGGYT-RKDKFNCV--EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
VN Y C GG R + + ++DEC+ C C NT GS+ C C G
Sbjct: 1623 -VNSTEYYTL-CPGGEGFRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQCECPQG 1679
Query: 441 Y--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELS 486
Y D C +DEC C C N G + C C E +++
Sbjct: 1680 YYLSEDTRICEDIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYMQVN 1726
Score = 46.0 bits (104), Expect = 4e-04
Identities = 51/188 (27%), Positives = 74/188 (39%), Gaps = 32/188 (17%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHH-CHS 380
+D C + C+N + C+C QG+ D C+D+DEC G+ G C++
Sbjct: 1650 IDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYN 1709
Query: 381 ---NTRCV------NVVGGYVCQ------CLGGYT-----RKDKFNCVEVDECEGNTHGC 420
N C+ V GG+ C C Y + FN + C G
Sbjct: 1710 TLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGK 1769
Query: 421 HADAVCTN--TPGSYT----CRCRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDG 472
+ C TPG+ C G+ D +T + +DEC E C + C+N G
Sbjct: 1770 AGNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGV-CINQIG 1828
Query: 473 GFRCECFT 480
FRCEC T
Sbjct: 1829 SFRCECPT 1836
Score = 41.1 bits (92), Expect = 0.012
Identities = 56/223 (25%), Positives = 72/223 (32%), Gaps = 25/223 (11%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP-GECCKFCPGVDYCNM 329
G RF C G QC +C C P + G+ C
Sbjct: 90 GSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQC 149
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVG 389
C TC + + C+C +G+ G T C E G +G C + C V G
Sbjct: 150 SVRCMNGGTCADDH----CQCQKGYIG---TYCGQPVC-ENGCQNGGRCIAQP-CACVYG 200
Query: 390 GYVCQCLGGYTRKDKFNCVEVDECEGNTHG--CHADAVCTNTPGSY--TCR--------C 437
QC Y F V C+G G C C T ++ C C
Sbjct: 201 FTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATTGRAWGHPCEMCPAQPQPC 260
Query: 438 RDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
R G+ + T C VDEC C C+N G F C C
Sbjct: 261 RRGFIPNIRTGACQDVDECQAIPGICQ-GGNCINTVGSFECRC 302
Score = 32.7 bits (71), Expect = 4.2
Identities = 32/122 (26%), Positives = 43/122 (35%), Gaps = 17/122 (13%)
Query: 249 HPGECCPTCLRQCLLWGNLYEHGERFAPKECAEC-----VCHDGNMQCTRVDPELACPRL 303
HP E CP + C + A ++ EC +C GN C C R
Sbjct: 248 HPCEMCPAQPQPCRR--GFIPNIRTGACQDVDECQAIPGICQGGN--CINTVGSFEC-RC 302
Query: 304 PCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTC 361
P Q E + C +D C++ E C N Y C C +G+ DG C
Sbjct: 303 PAGHKQS-----ETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRC 357
Query: 362 QD 363
D
Sbjct: 358 ID 359
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 143 bits (347), Expect = 2e-33
Identities = 76/219 (34%), Positives = 108/219 (49%), Gaps = 28/219 (12%)
Query: 281 ECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE--C-C----------KFC 321
EC C +G C +D P + CD Q ++PGE C C K C
Sbjct: 329 ECSCSEGYALMPDGRSCADIDECENNPDI-CDGGQCTNIPGEYRCLCYDGFMASMDMKTC 387
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHCH 379
V+ C++ + C N + C C G+ G T C DVDEC+ + H+C
Sbjct: 388 IDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECE----IGAHNCD 443
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C+N+ G + C C G+ C+++DEC TH C +A C NTPGSY C C +
Sbjct: 444 MHASCLNIPGSFKCSCREGWIGNG-IKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSE 502
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+TC VDEC E + C + +C+N+ G +RCEC
Sbjct: 503 GFTGDGFTCSDVDECAENINLC-ENGQCLNVPGAYRCEC 540
Score = 142 bits (344), Expect = 3e-33
Identities = 90/303 (29%), Positives = 133/303 (43%), Gaps = 22/303 (7%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C N + G + + +C C G E++ +C D EC
Sbjct: 209 GYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINEC 268
Query: 244 K--NPVLHPGECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPEL 298
+ + G+C QC +R + EC+ +G + QCT +
Sbjct: 269 SLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSY 328
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-- 356
C C G + C +D C + C N+ +Y C C GF
Sbjct: 329 ECS---CSEGYALMPDG---RSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASM 382
Query: 357 DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEG 415
D TC DV+EC L+ + C C N G ++C C GY+ +K C +VDECE
Sbjct: 383 DMKTCIDVNECD----LNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI 437
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
H C A C N PGS+ C CR+G+ G+G C+ +DEC+ G+H C +A+CVN G +R
Sbjct: 438 GAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYR 497
Query: 476 CEC 478
C C
Sbjct: 498 CAC 500
Score = 126 bits (304), Expect = 2e-28
Identities = 65/162 (40%), Positives = 84/162 (51%), Gaps = 13/162 (8%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C+ G H C NA C+N Y C C++GF GDG TC DVDEC E L C
Sbjct: 470 CIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINL----CE 525
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N +C+NV G Y C+C G+T D +C ++DEC + C N PG + C C
Sbjct: 526 -NGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC--SFQNICVFGTCNNLPGMFHCICD 582
Query: 439 DGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
DGYE D G C +DEC + + + CVN G + C C
Sbjct: 583 DGYELDRTGGNCTDIDECADPINCV--NGLCVNTPGRYECNC 622
Score = 126 bits (303), Expect = 3e-28
Identities = 65/163 (39%), Positives = 88/163 (53%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHH 377
C +D C+ C N C N Y C C +G+ Q DG TC+D+DECQ H+
Sbjct: 1553 CIDLDECSQSPKPC--NYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQ----HN 1606
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C CVN +GG+ C+C G+T+ C++ +EC C A +C NTPGS++C C
Sbjct: 1607 CQF--LCVNTLGGFTCKCPPGFTQHHTA-CIDNNECGSQPSLCGAKGICQNTPGSFSCEC 1663
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G+ D G C VDEC +G+H C H C NI GG+RC C
Sbjct: 1664 QRGFSLDATGLNCEDVDEC-DGNHRCQHG--CQNILGGYRCGC 1703
Score = 111 bits (267), Expect = 7e-24
Identities = 58/166 (34%), Positives = 78/166 (46%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C +D C TC+N + C C G + C D++EC + L
Sbjct: 218 KNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNL--- 274
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C N +CVN++G Y C C GY D+ C ++DEC GC D CTN+ GSY C
Sbjct: 275 -CR-NGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGC--DTQCTNSEGSYEC 330
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +GY DG +C +DEC C +C NI G +RC C+
Sbjct: 331 SCSEGYALMPDGRSCADIDECENNPDICD-GGQCTNIPGEYRCLCY 375
Score = 109 bits (262), Expect = 3e-23
Identities = 56/151 (37%), Positives = 79/151 (52%), Gaps = 16/151 (10%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C C N ++C+C +GF D GL C+DVDEC H C C N++GG
Sbjct: 1646 CGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG-----NHRCQHG--CQNILGG 1698
Query: 391 YVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-- 447
Y C C GY + ++N CV+ +EC N + C A C NT GSY C C G+ D ++
Sbjct: 1699 YRCGCPQGYIQHYQWNQCVDENECS-NPNAC-GSASCYNTLGSYKCACPSGFSFDQFSSA 1756
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C V+EC+ + C++ C N +GG+ C C
Sbjct: 1757 CHDVNECSSSKNPCNYG--CSNTEGGYLCGC 1785
Score = 107 bits (257), Expect = 1e-22
Identities = 58/160 (36%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C N TC N Y C C GF+ C D+DEC G C
Sbjct: 996 CMDVDECER-HPCG-NGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSS---FFGQVCR 1050
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N RC N +G + C C GY D NC++ +EC C + C N GS+ C C
Sbjct: 1051 -NGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSC-SPGTCQNLEGSFRCICP 1108
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE C+ ++EC E + C + C N GGF+C C
Sbjct: 1109 PGYEVKSENCIDINECDEDPNICLFGS-CTNTPGGFQCLC 1147
Score = 101 bits (241), Expect = 1e-20
Identities = 56/160 (35%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC G+ C +
Sbjct: 1236 VNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI-----GNPCGNG 1290
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+G + C C G+ NC +++EC N C C NT GSY C C GY
Sbjct: 1291 T-CTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFR--CMNTFGSYECTCPIGY 1347
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
D C +DEC EG H C C N+ G F C C
Sbjct: 1348 ALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 1387
Score = 99.5 bits (237), Expect = 3e-20
Identities = 51/158 (32%), Positives = 72/158 (45%), Gaps = 11/158 (6%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
+D C + + N C+N + C C G+ D G +C D+DEC ++ C N
Sbjct: 1514 IDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSP----KPC--N 1567
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C GY ++D C ++DEC+ H C +C NT G +TC+C G
Sbjct: 1568 YICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF--LCVNTLGGFTCKCPPG 1625
Query: 441 YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C+ +EC C C N G F CEC
Sbjct: 1626 FTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCEC 1663
Score = 97.9 bits (233), Expect = 1e-19
Identities = 51/160 (31%), Positives = 73/160 (45%), Gaps = 12/160 (7%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSN 381
+D C N C+N + C+C GF + L C+D+DEC L C N
Sbjct: 873 IDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNL----CQRN 928
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N G Y C+C G+ CV+ +EC + C + +C + GSY C C +G+
Sbjct: 929 ADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVC-SHGLCVDLQGSYQCICHNGF 987
Query: 442 EG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ D CM VDEC H C + C N G + C C+
Sbjct: 988 KASQDQTMCMDVDECER--HPCGNGT-CKNTVGSYNCLCY 1024
Score = 91.5 bits (217), Expect = 9e-18
Identities = 52/166 (31%), Positives = 81/166 (48%), Gaps = 13/166 (7%)
Query: 317 CCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ--DVDECQEAGGLH 374
CC + G + C+ T + K C GF D T + D+DEC+E G+
Sbjct: 827 CCTYNVGKAW---NKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGI- 882
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSY 433
C +N C+N +G + C+C G++ D C ++DEC + C +A C N+PGSY
Sbjct: 883 ---C-ANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSY 938
Query: 434 TCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C C G++ C+ +EC E + C H CV++ G ++C C
Sbjct: 939 RCECAAGFKLSPNGACVDRNECLEIPNVCSHGL-CVDLQGSYQCIC 983
Score = 91.1 bits (216), Expect = 1e-17
Identities = 57/182 (31%), Positives = 87/182 (47%), Gaps = 24/182 (13%)
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLT----C 361
P +F + CC G + G C+E + C GF +GD LT
Sbjct: 81 PGKFRMDACCCAV--GAAW---GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFY 135
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTHGC 420
+D++EC+ G+ C + +C N +G + C+C G+ ++ NC ++DEC + C
Sbjct: 136 KDINECKAFPGM----C-TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLC 190
Query: 421 HADAVCTNTPGSYTCRCRDGYEGDGY----TCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+C NTPGS+ C C +GYE G+ CM +DEC C CVN +G F+C
Sbjct: 191 -GSGICVNTPGSFECECFEGYE-SGFMMMKNCMDIDECERNPLLC-RGGTCVNTEGSFQC 247
Query: 477 EC 478
+C
Sbjct: 248 DC 249
Score = 85.4 bits (202), Expect = 6e-16
Identities = 68/225 (30%), Positives = 95/225 (42%), Gaps = 35/225 (15%)
Query: 240 RAECKNPV-LHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R EC L P C +CL N+ HG + +C+CH+G C
Sbjct: 939 RCECAAGFKLSPNGACVD-RNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCM 997
Query: 293 RVDPELACPRLPCDPPQQFSVPGECCKFC-PG-----------VDYCN--MGHSCDENAT 338
VD C R PC + G C PG +D C+ G C N
Sbjct: 998 DVDE---CERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVC-RNGR 1053
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C CN+G++ DG C D +EC G C T C N+ G + C C
Sbjct: 1054 CFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPG----SCSPGT-CQNLEGSFRCICP 1108
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
GY K + NC++++EC+ + + C + CTNTPG + C C G+
Sbjct: 1109 PGYEVKSE-NCIDINECDEDPNICLFGS-CTNTPGGFQCLCPPGF 1151
Score = 78.2 bits (184), Expect = 9e-14
Identities = 43/125 (34%), Positives = 60/125 (48%), Gaps = 11/125 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C VD C + EN C+N+ Y C+C GF D +CQD+DEC + C
Sbjct: 511 CSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-----FQNIC 565
Query: 379 HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
T C N+ G + C C GY + NC ++DEC + C + +C NTPG Y C C
Sbjct: 566 VFGT-CNNLPGMFHCICDDGYELDRTGGNCTDIDEC-ADPINC-VNGLCVNTPGRYECNC 622
Query: 438 RDGYE 442
++
Sbjct: 623 PPDFQ 627
Score = 74.9 bits (176), Expect = 8e-13
Identities = 79/290 (27%), Positives = 114/290 (39%), Gaps = 44/290 (15%)
Query: 224 CSCVHGEITCRPVEC-DRAEC-KNPVLHPGECCPTC-LRQCLL-WGNLYEHGERFAPK-- 277
C+C G + C D EC +NP+L C T +C G ++
Sbjct: 1301 CNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLD 1360
Query: 278 ECAECV--CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE + C M C + C C P GE C + C E
Sbjct: 1361 ECAEGLHDCESRGMMCKNLIGTFMCI---CPPGMARRPDGEGCV---DENECRTKPGICE 1414
Query: 336 NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDE-----------CQEAGGLHGHHCHSNT 382
N C+N+ Y C+CN+GFQ G C D + CQ A S
Sbjct: 1415 NGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSEC 1474
Query: 383 RCVNVVG-GYVCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTP 430
C G G+ C+ C T + K C ++DEC+ + C + C NT
Sbjct: 1475 CCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLC-TNGQCINTM 1533
Query: 431 GSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GS+ C C+ GY D G +C+ +DEC++ C++ C N +G ++C C
Sbjct: 1534 GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYI--CKNTEGSYQCSC 1581
Score = 71.3 bits (167), Expect = 1e-11
Identities = 42/125 (33%), Positives = 58/125 (46%), Gaps = 15/125 (12%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C VD C+ H C C N+ Y C C QG+ C D +EC C
Sbjct: 1676 CEDVDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA-----C 1728
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
S + C N +G Y C C G++ D+F+ C +V+EC + + C+ C+NT G Y C
Sbjct: 1729 GSAS-CYNTLGSYKCACPSGFSF-DQFSSACHDVNECSSSKNPCNYG--CSNTEGGYLCG 1784
Query: 437 CRDGY 441
C GY
Sbjct: 1785 CPPGY 1789
Score = 55.2 bits (127), Expect = 7e-07
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSAR 466
+++EC+ C C NT GS+ CRC G+ D C +DEC C S
Sbjct: 137 DINECKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCG-SGI 194
Query: 467 CVNIDGGFRCECF 479
CVN G F CECF
Sbjct: 195 CVNTPGSFECECF 207
Score = 54.0 bits (124), Expect = 2e-06
Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHC 378
C + C+ ++C +A+C N Y C C GF D + C DV+EC + + C
Sbjct: 1716 CVDENECSNPNACG-SASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK----NPC 1770
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
N C N GGY+C C GY R + +CV
Sbjct: 1771 --NYGCSNTEGGYLCGCPPGYYRVGQGHCV 1798
Score = 49.2 bits (112), Expect = 5e-05
Identities = 83/334 (24%), Positives = 113/334 (33%), Gaps = 57/334 (17%)
Query: 184 KLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDC-NRCSCVHGEITCRPV-ECDRA 241
KL A + R E + C V G+ +Q C N + C V EC+R
Sbjct: 947 KLSPNGACVDRNECLEIPNVCSHGLCVDLQGS-YQCICHNGFKASQDQTMCMDVDECERH 1005
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAEC---VCHDGNMQCTRVDPEL 298
C N CL C L + + EC+ VC +G R E+
Sbjct: 1006 PCGNGTCKNTVGSYNCL--CYPGFELTHNNDCLDIDECSSFFGQVCRNG-----RCFNEI 1058
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
+ C+ + + G K C + C + SC TC NL + C C G++
Sbjct: 1059 GSFKCLCNEGYELTPDG---KNCIDTNECVALPGSCSPG-TCQNLEGSFRCICPPGYEVK 1114
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDE--CE 414
C D++EC E + C + C N GG+ C C G+ D C + + C
Sbjct: 1115 SENCIDINECDEDPNI----CLFGS-CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCF 1169
Query: 415 GNTHG--CHADAVCTNTPGSYTCRCRDGYEGDGYTC---------MHVDECTEGSHT--- 460
N C T C G EG G C D C G T
Sbjct: 1170 TNFENGKCSVPKAFNTTKAKCCCSKMPG-EGWGDPCELCPKDDEVAFQDLCPYGHGTVPS 1228
Query: 461 ----------CHHS------ARCVNIDGGFRCEC 478
C S +C+N DG FRCEC
Sbjct: 1229 LHDTREDVNECLESPGICSNGQCINTDGSFRCEC 1262
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/228 (28%), Positives = 86/228 (37%), Gaps = 38/228 (16%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
C+C DG CT +D E A P + C V G C PG CN
Sbjct: 579 CICDDGYELDRTGGNCTDID-ECADP-INC-------VNGLCVN-TPGRYECNCPPDFQL 628
Query: 336 NAT---CMNLNTKYTCKCNQGFQGDG-LTCQD-----VDE---CQEAGGLHGHHCHSNTR 383
N T C++ N C G +GDG L+C V C G G+ C +
Sbjct: 629 NPTGVGCVD-NRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPP 687
Query: 384 CVNVVGGYVCQCLGGYT-RKDKFNCV--EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
VN Y C GG R + + ++DEC+ C C NT GS+ C C G
Sbjct: 688 -VNSTEYYTL-CPGGEGFRPNPITIILEDIDECQELPGLCQGGN-CINTFGSFQCECPQG 744
Query: 441 Y--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELS 486
Y D C +DEC C C N G + C C E +++
Sbjct: 745 YYLSEDTRICEDIDECFAHPGVC-GPGTCYNTLGNYTCICPPEYMQVN 791
Score = 45.2 bits (102), Expect = 7e-04
Identities = 51/180 (28%), Positives = 66/180 (36%), Gaps = 21/180 (11%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQ 362
C+ PQ + + E + C +D C TC N YTC C + G C
Sbjct: 739 CECPQGYYL-SEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCM 797
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
D+ + +G C N NV C C Y +N CE A
Sbjct: 798 DMRKSFCYRSYNGTTCE-NELPFNVTKRMCC-CT--YNVGKAWN----KPCEPCPTPGTA 849
Query: 423 D--AVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
D +C N PG +T G D +DEC E C + C+N G FRCEC T
Sbjct: 850 DFKTICGNIPG-FTFDIHTGKAVD------IDECKEIPGICANGV-CINQIGSFRCECPT 901
Score = 40.3 bits (90), Expect = 0.021
Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 4/96 (4%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
C G R C +V+ECE C + C N+ GS+ C C +G DG + +D
Sbjct: 5 CPRGLARIKGVTCEDVNECEVFPGVC-PNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIR 63
Query: 455 TEGSHTCHHSARCVN-IDGGFRCECFTENCELSCSW 489
E + C++ + G FR + C + +W
Sbjct: 64 MEQCYLKWDEDECIHPVPGKFRMDACC--CAVGAAW 97
Score = 38.7 bits (86), Expect = 0.064
Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 5/43 (11%)
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
G+TC+DV+EC+ G+ C N RCVN G + C+C G T
Sbjct: 14 GVTCEDVNECEVFPGV----C-PNGRCVNSKGSFHCECPEGLT 51
Score = 31.5 bits (68), Expect = 9.7
Identities = 55/224 (24%), Positives = 83/224 (37%), Gaps = 40/224 (17%)
Query: 197 QCDCQKS-CYSNGTVHADGATWQRDCNRCSCVHGE-ITCRPV-ECD---RAE--CKNPVL 248
+C Q S C + G ++ +C R + + C V ECD R + C+N +L
Sbjct: 1638 ECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGCQN-IL 1696
Query: 249 HPGEC-CPTCLRQCLLWGNLYEHGERFAPKECAECVCHD--GNMQCTRVDPELACPRLPC 305
C CP Q W + E P C C++ G+ +C AC
Sbjct: 1697 GGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKC-------AC----- 1744
Query: 306 DPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
P FS + C V+ C+ + C N C N Y C C G+ G
Sbjct: 1745 --PSGFSF-DQFSSACHDVNECSSSKNPC--NYGCSNTEGGYLCGCPPGYYRVG-----Q 1794
Query: 365 DECQEAGGLH-GHHCHSNTRC--VNVVGGYVC-QC-LGGYTRKD 403
C G + G + +T N + C +C + GY++KD
Sbjct: 1795 GHCVSGMGFNKGQYLSLDTEVDEENALSPEACYECKINGYSKKD 1838
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 142 bits (344), Expect = 3e-33
Identities = 94/302 (31%), Positives = 126/302 (41%), Gaps = 20/302 (6%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C + + G D + +C C G E+T + C D EC
Sbjct: 1058 GYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDEC 1117
Query: 244 K-NPVLHP-GECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELAC 300
+ L P G+C QC +R + EC +G ++ E
Sbjct: 1118 SLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GS 1176
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DG 358
R C G C VD C + C N+ + C C GF D
Sbjct: 1177 YRCSCGQGYSLMPDGRACA---DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDM 1233
Query: 359 LTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGN 416
TC DVDEC L+ H C H + C N G +VC C GY RK C +VDECE
Sbjct: 1234 RTCVDVDECD----LNPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 417 THGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
H C + A C N PGS++CRC G+ GDG+ C +DEC H C C+N+ G +RC
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC 1347
Query: 477 EC 478
C
Sbjct: 1348 TC 1349
Score = 140 bits (339), Expect = 1e-32
Identities = 65/160 (40%), Positives = 85/160 (53%), Gaps = 8/160 (5%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHC 378
C VD C++ + C N + C C G+ G T C DVDEC E GG H+C
Sbjct: 1236 CVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC-EVGG---HNC 1291
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ C+N+ G + C+CL G+ D F C ++DEC H C C N PGSY C CR
Sbjct: 1292 DSHASCLNIPGSFSCRCLPGWVG-DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+ C DEC E C + +C+N GG+RCEC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCEC 1389
Score = 124 bits (300), Expect = 8e-28
Identities = 63/166 (37%), Positives = 80/166 (48%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C VD C TC N + Y C+C G + G C+D+DEC + GL H
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH 1126
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+CVNV+G + C C G+ + D+ CV+++EC GC D C NT GSY C
Sbjct: 1127 G-----QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRC 1179
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C GY DG C VDEC E C C N+ GG RC C+
Sbjct: 1180 SCGQGYSLMPDGRACADVDECEENPRVCDQG-HCTNMPGGHRCLCY 1224
Score = 115 bits (277), Expect = 5e-25
Identities = 68/178 (38%), Positives = 91/178 (51%), Gaps = 16/178 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C + H C C+N+ Y C C QGF GDG C+D DEC E L C
Sbjct: 1319 CHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL----C- 1373
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
N +C+N GGY C+C G+ +D C +VDEC +GN C A C N PG + C C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL--C-AFGSCENLPGMFRCIC 1430
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRV 493
GYE D G C ++EC + + C + C+N G + C C ++ EL+ S G V
Sbjct: 1431 NGGYELDRGGGNCTDINECADPVN-CINGV-CINTPGSYLCSC-PQDFELNPSGVGCV 1485
Score = 114 bits (275), Expect = 8e-25
Identities = 75/209 (35%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 278 ECAEC--VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE VC +G C D C C P +S+ C D C++GH C +
Sbjct: 2087 ECAENPGVCTNG--VCVNTDGSFRCE---C--PFGYSLDFTGIN-CVDTDECSVGHPCGQ 2138
Query: 336 NATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
TC N+ + C C GF+ G +TC+D+DEC L CH N G Y+C
Sbjct: 2139 G-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCH------NTEGSYLCT 2191
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAV-CTNTPGSYTCRCRDGYE---GDGYTCM 449
C GYT R+D C +VDEC CHA + C N G++ C C G G G C
Sbjct: 2192 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC C + RCVN G FRC+C
Sbjct: 2252 DDNECHAQPDLCVNG-RCVNTAGSFRCDC 2279
Score = 111 bits (267), Expect = 7e-24
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 14/144 (9%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C C +G+ + DG TC+D+DEC H+C CVN VG + C+C
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS----RQHNCQF--LCVNTVGAFTCRCP 2473
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDEC 454
G+T+ + C + DEC C A C NTPGS+ C C G+ G+ C V+EC
Sbjct: 2474 PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
+G H C H C N GG+RC C
Sbjct: 2533 -DGPHRCQHG--CQNQLGGYRCSC 2553
Score = 111 bits (266), Expect = 1e-23
Identities = 59/160 (36%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC GH C
Sbjct: 2085 VNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-----GHPCGQG 2139
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+GG+ C C G+ C ++DEC N C C NT GSY C C GY
Sbjct: 2140 T-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGY 2196
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
DG C VDEC +G CH C N+ G F C C
Sbjct: 2197 TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Score = 108 bits (260), Expect = 5e-23
Identities = 94/311 (30%), Positives = 125/311 (40%), Gaps = 39/311 (12%)
Query: 193 SRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD------RAECKNP 246
S E+C+ +C + G G T D N C G C C R EC
Sbjct: 844 SPCERCEIDPAC-ARGFARMTGVTCD-DVNECESFPG--VCPNGRCVNTAGSFRCECPEG 899
Query: 247 VLHPGE---CCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDG---NMQCTRV-DPEL 298
++ C L C L + E G K + C C G ++C DPE
Sbjct: 900 LMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPES 959
Query: 299 A-----CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
CPR + F + G F V+ C + + TC N + C C G
Sbjct: 960 LEFASLCPRGLGFASRDF-LSGR--PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGG 1016
Query: 354 FQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF--NCVE 409
F D C D+DEC+ + L C T CVN G + C+C GY NC++
Sbjct: 1017 FALDAQERNCTDIDECRISPDL----CGQGT-CVNTPGSFECECFPGYESGFMLMKNCMD 1071
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARC 467
VDEC + C CTNT GSY C+C G+E G C +DEC+ C H +C
Sbjct: 1072 VDECARDPLLCRG-GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQC 1129
Query: 468 VNIDGGFRCEC 478
VN+ G F+C C
Sbjct: 1130 VNVIGAFQCSC 1140
Score = 107 bits (256), Expect = 2e-22
Identities = 69/183 (37%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-- 359
R C+ V GEC VD C C + C+N+ Y C+C GFQ
Sbjct: 432 RCECNVGYTQDVRGECID----VDECTSS-PC-HHGDCVNIPGTYHCRCYPGFQATPTRQ 485
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTH 418
C DVDEC +GGL CH RCVN G + C C G+ D NCV+ +EC +T
Sbjct: 486 ACVDVDECIVSGGL----CHLG-RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 419 GCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
C + VC N GS++C C+ G+ G+ CM +DEC T G H C N +G FR
Sbjct: 541 -C-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH---CTNTEGSFR 595
Query: 476 CEC 478
C+C
Sbjct: 596 CQC 598
Score = 103 bits (247), Expect = 2e-21
Identities = 67/205 (32%), Positives = 85/205 (41%), Gaps = 19/205 (9%)
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG--VDYCNM-GHSCDEN 336
AEC C G R + CP LP + P G VD C M H C +
Sbjct: 2322 AECCCGGGRGWGPRCE---LCP-LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AH 2376
Query: 337 ATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N + C C G+ D TC D+DEC + C C N G ++C
Sbjct: 2377 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP----KPC--TFLCKNTKGSFLCS 2430
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C GY +D C ++DEC H C +C NT G++TCRC G+ C DE
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDNDE 2488
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
C+ C C N G FRCEC
Sbjct: 2489 CSAQPGPCGAHGHCHNTPGSFRCEC 2513
Score = 99 bits (238), Expect = 2e-20
Identities = 56/161 (34%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSN 381
+D C + N C+N + C+C GF + L C+DVDEC G C N
Sbjct: 1722 IDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC----GSRESPCQQN 1777
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDG 440
C+N+ G Y C+C GY CV +EC + C H D C +T GSY C C G
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGD--CMDTEGSYMCLCHRG 1835
Query: 441 YE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
++ D CM +DEC C + C NI G + C CF
Sbjct: 1836 FQASADQTLCMDIDECDR--QPCGNGT-CKNIIGSYNCLCF 1873
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/159 (35%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNT 382
+D C + N C+ + Y C+CN G+ D C DVDEC + HG
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD------ 462
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN+ G Y C+C G+ + CV+VDEC + CH C NT GS+ C C G+
Sbjct: 463 -CVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAGF 520
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E DG C+ +EC S C + C+N DG F C C
Sbjct: 521 ELSPDGKNCVDHNECAT-STMCVNGV-CLNEDGSFSCLC 557
Score = 95.5 bits (227), Expect = 5e-19
Identities = 70/220 (31%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 265 GNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV 324
G L E R K+ EC N Q V+ A C P F+ + C
Sbjct: 2434 GYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGA---FTCRCPPGFTQHHQACF---DN 2486
Query: 325 DYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
D C+ C + C N + C+C+QGF G C+DV+EC H C
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGP-----HRCQHG 2541
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N +GGY C C G+T+ ++ CV+ +EC + C A C NT G + C C G
Sbjct: 2542 --CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC-GSASCRNTLGGFRCVCPSG 2598
Query: 441 YEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++ D C VDEC C +S C N GGF C C
Sbjct: 2599 FDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGC 2636
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/178 (31%), Positives = 81/178 (45%), Gaps = 13/178 (7%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQ 362
C+ P F+ C VD C S C +NA C+N+ Y CKC +G++ G C
Sbjct: 1746 CECPAGFNY-NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACV 1804
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
+EC+E + C S+ C++ G Y+C C G+ D+ C+++DEC+ G
Sbjct: 1805 GRNECREIPNV----C-SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG-- 1857
Query: 422 ADAVCTNTPGSYTCRCRDGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C N GSY C C G+ C+ DECT C+N G F C C
Sbjct: 1858 -NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLC 1914
Score = 91.1 bits (216), Expect = 1e-17
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGDGLTCQDVDECQEAGGLHGH 376
C +D C+ C N TC N+ Y C C GF GD C D DEC L G
Sbjct: 1845 CMDIDECDR-QPCG-NGTCKNIIGSYNCLCFPGFVVTHNGD---CVDFDECTT---LVGQ 1896
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N G + C C G+ D NCV+ +EC C C N GS+ C
Sbjct: 1897 VCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPGTCQNLEGSFRC 1954
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ C+ +DEC+E + C C N G F+C C
Sbjct: 1955 ICPPGFQVQSDHCIDIDECSEEPNLCLFGT-CTNSPGSFQCLC 1996
Score = 90.2 bits (214), Expect = 2e-17
Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHH 377
C +D C + TC+N + C+C G++ + C DVDEC L
Sbjct: 1026 CTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLL---- 1081
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C T C N G Y CQC G+ K C ++DEC + G C N G++ C
Sbjct: 1082 CRGGT-CTNTDGSYKCQCPPGHELTAKGTACEDIDEC-SLSDGLCPHGQCVNVIGAFQCS 1139
Query: 437 CRDGYEG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C+ ++EC + C C+N +G +RC C
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRCSC 1181
Score = 85.0 bits (201), Expect = 7e-16
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCH 421
D+DEC E + C +N C+N +G + C+C G+ C +VDEC C
Sbjct: 1721 DIDECGEIPAI----C-ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 422 ADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+A C N PGSY C+C GY+ G C+ +EC E + C H C++ +G + C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH-GDCMDTEGSYMCLC 1832
Score = 83.0 bits (196), Expect = 3e-15
Identities = 59/179 (32%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLP----CDPPQQFSVPGECCKFCPGVDY 326
G+ F + ECV + R P C +P C Q F+ G FC D
Sbjct: 1314 GDGFECHDLDECVSQEH-----RCSPRGDCLNVPGSYRCTCRQGFAGDGF---FCEDRDE 1365
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +N C+N Y C+C GF D CQDVDEC + G+ C + C
Sbjct: 1366 CAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-----GNLCAFGS-C 1419
Query: 385 VNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
N+ G + C C GGY + NC +++EC + C + VC NTPGSY C C +E
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVN-C-INGVCINTPGSYLCSCPQDFE 1476
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/165 (35%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ G C DVDEC L+ C N
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC----ALNSLLC-DN 737
Query: 382 TRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C G+ +D C +VDEC + C VC N GSYTC+C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--C-VSGVCRNLAGSYTCKCGPG 794
Query: 441 YEGD--GYTCMHVDECTEGSHTCH---HSARC-VNIDG-GFRCEC 478
D G C+ + T+G TC +RC VN+ G R EC
Sbjct: 795 SRLDPSGTFCL---DSTKG--TCWLKIQESRCEVNLQGASLRSEC 834
Score = 77.8 bits (183), Expect = 1e-13
Identities = 65/234 (27%), Positives = 94/234 (40%), Gaps = 37/234 (15%)
Query: 240 RAEC-KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R +C + L PG C +C N+ HG+ + C+CH G C
Sbjct: 1788 RCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCM 1846
Query: 293 RVDPELACPRLPCDPPQQFSVPGE--CCKF----------CPGVDYCN--MGHSCDENAT 338
+D C R PC ++ G C F C D C +G C
Sbjct: 1847 DIDE---CDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGH 1902
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C+N + C C GF+ DG C D +EC G C T C N+ G + C C
Sbjct: 1903 CLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT----CLPGT-CQNLEGSFRCICP 1957
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTC 448
G+ + +C+++DEC + C CTN+PGS+ C C G+ +G+ C
Sbjct: 1958 PGFQVQSD-HCIDIDECSEEPNLC-LFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 75.8 bits (178), Expect = 5e-13
Identities = 60/207 (28%), Positives = 84/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT +C + GE EC CH G+ C + C C P
Sbjct: 422 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD--CVNIPGTYHCR---CYP 476
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q + + C VD C + C+N + C CN GF+ DG C D +
Sbjct: 477 GFQATPTRQACV---DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHN 533
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ + C+++DEC+ T G +
Sbjct: 534 ECATST-----MC-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ--TPGICVNG 585
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCM 449
CTNT GS+ C+C G DG C+
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCV 612
Score = 73.3 bits (172), Expect = 2e-12
Identities = 44/122 (36%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C+ H C C N Y C C QGF Q VDE + A L C S
Sbjct: 2526 CEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGS 2581
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N +GG+ C C G+ C +VDEC G C C NTPG + C C
Sbjct: 2582 AS-CRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGCPQ 2638
Query: 440 GY 441
GY
Sbjct: 2639 GY 2640
Score = 72.5 bits (170), Expect = 4e-12
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 35/190 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGG 372
G K C VD C + +N C N Y+C C GF D C+DVDEC +
Sbjct: 716 GASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSS-- 773
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD----------KFNC---VEVDECEGNTHG 419
C S C N+ G Y C+C G +R D K C ++ CE N G
Sbjct: 774 ----PCVSGV-CRNLAGSYTCKC-GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQG 827
Query: 420 CHADAVCTNTPGS---YTCR-------CRDGY-EGDGYTCMHVDECTEGSHTCHHSARCV 468
+ C T G+ C C G+ G TC V+EC C + RCV
Sbjct: 828 ASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCV 886
Query: 469 NIDGGFRCEC 478
N G FRCEC
Sbjct: 887 NTAGSFRCEC 896
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 11/125 (8%)
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNV 387
G+ C+ + C +GFQ + +T +D+DECQE GL C CVN
Sbjct: 1528 GNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL----CQGGD-CVNT 1582
Query: 388 VGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGD 444
G + C+C GY + C ++DEC ++ C C NT G+YTC C Y
Sbjct: 1583 FGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYNTLGNYTCVCPAEYLQVNG 1641
Query: 445 GYTCM 449
G CM
Sbjct: 1642 GNNCM 1646
Score = 65.7 bits (153), Expect = 5e-10
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C++ C N Y C C G+ + DG C+DVDEC + C
Sbjct: 2164 CEDIDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ----QDC 2218
Query: 379 HSN-TRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC 435
H+ C N++G + C C G C + +EC C + C NT GS+ C
Sbjct: 2219 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFRC 2277
Query: 436 RCRDGYE 442
C +G++
Sbjct: 2278 DCDEGFQ 2284
Score = 59.7 bits (138), Expect = 3e-08
Identities = 31/71 (43%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCV 468
+D C T+ C + C TP SY C C GY D C+ VDECT S CHH CV
Sbjct: 409 IDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGD-CV 464
Query: 469 NIDGGFRCECF 479
NI G + C C+
Sbjct: 465 NIPGTYHCRCY 475
Score = 56.8 bits (131), Expect = 2e-07
Identities = 65/229 (28%), Positives = 84/229 (36%), Gaps = 39/229 (17%)
Query: 278 ECA-ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA +C +G C D +C C P + G +C +D C C N
Sbjct: 534 ECATSTMCVNG--VCLNEDGSFSCL---CKPGFLLAPGGH---YCMDIDECQTPGIC-VN 584
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDV---DECQ---EAGG----LHGHHCHSNTRC 384
C N + C+C G DG C D C E G G S C
Sbjct: 585 GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 385 VNVVGGY--VCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTPG 431
N G+ CQ C + + + C +++EC + C A+ VC N G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVC-ANGVCENLRG 703
Query: 432 SYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SY C C GYE G C VDEC S C + C N G + C C
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLC-DNGWCQNSPGSYSCSC 751
Score = 55.6 bits (128), Expect = 5e-07
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQ 362
C PQ F+ + + C + C + +A+C N + C C GF D CQ
Sbjct: 2551 CSCPQGFTQHSQWAQ-CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2609
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
DVDEC G G +S C N GG++C C GY R + +CV
Sbjct: 2610 DVDEC---AGRRGPCSYS---CANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 54.4 bits (125), Expect = 1e-06
Identities = 67/245 (27%), Positives = 88/245 (35%), Gaps = 41/245 (16%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSC- 333
CVC+ G CT VD E A L CD + PG C PG + C
Sbjct: 707 CVCNLGYEAGASGKDCTDVD-ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765
Query: 334 --DE-------NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN- 381
DE + C NL YTCKC G + D G C D + + C N
Sbjct: 766 DVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNL 825
Query: 382 ------TRCVNVVG---GYVCQ-------CLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
+ C +G G C+ C G+ R C +V+ECE C +
Sbjct: 826 QGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGR 884
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC-VNIDGGFRCECFTENCE 484
C NT GS+ C C +G D + VD E C V + G +R + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCC--CS 942
Query: 485 LSCSW 489
+ W
Sbjct: 943 IGAVW 947
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 35/213 (16%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-- 357
C R DP C V+ C N C+N + C+C +G D
Sbjct: 846 CERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 905
Query: 358 GLTCQDV-----------DECQ--------------EAGGLHGHHCHSNTRCVNVVGGYV 392
G C DV DEC G + G C + ++ +
Sbjct: 906 GRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASL 965
Query: 393 CQCLGGYTRKDKFN----CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-- 446
C G+ +D + +V+EC+ C C NT GS+ C C G+ D
Sbjct: 966 CPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC C CVN G F CECF
Sbjct: 1025 NCTDIDECRISPDLCGQGT-CVNTPGSFECECF 1056
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/225 (28%), Positives = 82/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGVDYCNM 329
G RF C G QC AC C P + G C GV +
Sbjct: 61 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSC-GV---SR 116
Query: 330 GHSCDENATCMNLNT--KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
G C + +CMN T +C C +G+ G + Q + C + G +G C RC V
Sbjct: 117 GSGC--SVSCMNGGTCRGASCLCQKGYTGT-VCGQPI--C-DRGCHNGGRCIGPNRCACV 170
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHAD-AVCTNTPG---SYTCR------- 436
G QC Y F V + C+ G A+C T G C
Sbjct: 171 YGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 230
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + +T C VDEC C + CVN+ G F C C
Sbjct: 231 PCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRC 274
Score = 49.2 bits (112), Expect = 5e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ C C GY +T C +DEC+ S C
Sbjct: 1563 DIDECQELPGLCQGGD-CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGT 1620
Query: 467 CVNIDGGFRCECFTENCELS 486
C N G + C C E +++
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVN 1640
Score = 48.4 bits (110), Expect = 8e-05
Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 23/226 (10%)
Query: 184 KLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEIT-CRPV-ECDRA 241
KL A + R E + C + +G+ + C+R + T C + ECDR
Sbjct: 1796 KLSPGGACVGRNECREIPNVCSHGDCMDTEGS-YMCLCHRGFQASADQTLCMDIDECDRQ 1854
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECV---CHDGNMQCTRVDPEL 298
C N CL C + +G+ EC V C G+ C
Sbjct: 1855 PCGNGTCKNIIGSYNCL--CFPGFVVTHNGDCVDFDECTTLVGQVCRFGH--CLNTAGSF 1910
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
C C + + G K C + C ++ +C TC NL + C C GFQ
Sbjct: 1911 HCL---CQDGFELTADG---KNCVDTNECLSLAGTCLPG-TCQNLEGSFRCICPPGFQVQ 1963
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C D+DEC E L C T C N G + C C G+ D
Sbjct: 1964 SDHCIDIDECSEEPNL----CLFGT-CTNSPGSFQCLCPPGFVLSD 2004
Score = 44.0 bits (99), Expect = 0.002
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ T C+D+DEC H C
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDEC----STHSSICGPG 1619
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N +G Y C C Y + NC+++
Sbjct: 1620 T-CYNTLGNYTCVCPAEYLQVNGGNNCMDM 1648
Score = 42.3 bits (95), Expect = 0.005
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 350 CNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C +GF + T CQDVDECQ GL C + CVN+VG + C+C G+ D
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGL----CQGGS-CVNMVGSFHCRCPVGHRLSD 282
Score = 33.1 bits (72), Expect = 3.2
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C +VDEC+ C + C N GS+ CRC G+
Sbjct: 245 CQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGH 278
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 142 bits (344), Expect = 3e-33
Identities = 94/302 (31%), Positives = 126/302 (41%), Gaps = 20/302 (6%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C + + G D + +C C G E+T + C D EC
Sbjct: 1058 GYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDEC 1117
Query: 244 K-NPVLHP-GECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELAC 300
+ L P G+C QC +R + EC +G ++ E
Sbjct: 1118 SLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GS 1176
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DG 358
R C G C VD C + C N+ + C C GF D
Sbjct: 1177 YRCSCGQGYSLMPDGRACA---DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDM 1233
Query: 359 LTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGN 416
TC DVDEC L+ H C H + C N G +VC C GY RK C +VDECE
Sbjct: 1234 RTCVDVDECD----LNPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 417 THGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
H C + A C N PGS++CRC G+ GDG+ C +DEC H C C+N+ G +RC
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC 1347
Query: 477 EC 478
C
Sbjct: 1348 TC 1349
Score = 140 bits (339), Expect = 1e-32
Identities = 65/160 (40%), Positives = 85/160 (53%), Gaps = 8/160 (5%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHC 378
C VD C++ + C N + C C G+ G T C DVDEC E GG H+C
Sbjct: 1236 CVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC-EVGG---HNC 1291
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ C+N+ G + C+CL G+ D F C ++DEC H C C N PGSY C CR
Sbjct: 1292 DSHASCLNIPGSFSCRCLPGWVG-DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+ C DEC E C + +C+N GG+RCEC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCEC 1389
Score = 124 bits (300), Expect = 8e-28
Identities = 63/166 (37%), Positives = 80/166 (48%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C VD C TC N + Y C+C G + G C+D+DEC + GL H
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH 1126
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+CVNV+G + C C G+ + D+ CV+++EC GC D C NT GSY C
Sbjct: 1127 G-----QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRC 1179
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C GY DG C VDEC E C C N+ GG RC C+
Sbjct: 1180 SCGQGYSLMPDGRACADVDECEENPRVCDQG-HCTNMPGGHRCLCY 1224
Score = 115 bits (277), Expect = 5e-25
Identities = 68/178 (38%), Positives = 91/178 (51%), Gaps = 16/178 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C + H C C+N+ Y C C QGF GDG C+D DEC E L C
Sbjct: 1319 CHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL----C- 1373
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
N +C+N GGY C+C G+ +D C +VDEC +GN C A C N PG + C C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL--C-AFGSCENLPGMFRCIC 1430
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRV 493
GYE D G C ++EC + + C + C+N G + C C ++ EL+ S G V
Sbjct: 1431 NGGYELDRGGGNCTDINECADPVN-CINGV-CINTPGSYLCSC-PQDFELNPSGVGCV 1485
Score = 114 bits (275), Expect = 8e-25
Identities = 75/209 (35%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 278 ECAEC--VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE VC +G C D C C P +S+ C D C++GH C +
Sbjct: 2087 ECAENPGVCTNG--VCVNTDGSFRCE---C--PFGYSLDFTGIN-CVDTDECSVGHPCGQ 2138
Query: 336 NATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
TC N+ + C C GF+ G +TC+D+DEC L CH N G Y+C
Sbjct: 2139 G-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCH------NTEGSYLCT 2191
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAV-CTNTPGSYTCRCRDGYE---GDGYTCM 449
C GYT R+D C +VDEC CHA + C N G++ C C G G G C
Sbjct: 2192 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC C + RCVN G FRC+C
Sbjct: 2252 DDNECHAQPDLCVNG-RCVNTAGSFRCDC 2279
Score = 111 bits (267), Expect = 7e-24
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 14/144 (9%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C C +G+ + DG TC+D+DEC H+C CVN VG + C+C
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS----RQHNCQF--LCVNTVGAFTCRCP 2473
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDEC 454
G+T+ + C + DEC C A C NTPGS+ C C G+ G+ C V+EC
Sbjct: 2474 PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
+G H C H C N GG+RC C
Sbjct: 2533 -DGPHRCQHG--CQNQLGGYRCSC 2553
Score = 111 bits (266), Expect = 1e-23
Identities = 59/160 (36%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC GH C
Sbjct: 2085 VNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-----GHPCGQG 2139
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+GG+ C C G+ C ++DEC N C C NT GSY C C GY
Sbjct: 2140 T-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGY 2196
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
DG C VDEC +G CH C N+ G F C C
Sbjct: 2197 TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Score = 108 bits (260), Expect = 5e-23
Identities = 94/311 (30%), Positives = 125/311 (40%), Gaps = 39/311 (12%)
Query: 193 SRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD------RAECKNP 246
S E+C+ +C + G G T D N C G C C R EC
Sbjct: 844 SPCERCEIDPAC-ARGFARMTGVTCD-DVNECESFPG--VCPNGRCVNTAGSFRCECPEG 899
Query: 247 VLHPGE---CCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDG---NMQCTRV-DPEL 298
++ C L C L + E G K + C C G ++C DPE
Sbjct: 900 LMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPES 959
Query: 299 A-----CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
CPR + F + G F V+ C + + TC N + C C G
Sbjct: 960 LEFASLCPRGLGFASRDF-LSGR--PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGG 1016
Query: 354 FQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF--NCVE 409
F D C D+DEC+ + L C T CVN G + C+C GY NC++
Sbjct: 1017 FALDAQERNCTDIDECRISPDL----CGQGT-CVNTPGSFECECFPGYESGFMLMKNCMD 1071
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARC 467
VDEC + C CTNT GSY C+C G+E G C +DEC+ C H +C
Sbjct: 1072 VDECARDPLLCRG-GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQC 1129
Query: 468 VNIDGGFRCEC 478
VN+ G F+C C
Sbjct: 1130 VNVIGAFQCSC 1140
Score = 107 bits (256), Expect = 2e-22
Identities = 69/183 (37%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-- 359
R C+ V GEC VD C C + C+N+ Y C+C GFQ
Sbjct: 432 RCECNVGYTQDVRGECID----VDECTSS-PC-HHGDCVNIPGTYHCRCYPGFQATPTRQ 485
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTH 418
C DVDEC +GGL CH RCVN G + C C G+ D NCV+ +EC +T
Sbjct: 486 ACVDVDECIVSGGL----CHLG-RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 419 GCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
C + VC N GS++C C+ G+ G+ CM +DEC T G H C N +G FR
Sbjct: 541 -C-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH---CTNTEGSFR 595
Query: 476 CEC 478
C+C
Sbjct: 596 CQC 598
Score = 103 bits (247), Expect = 2e-21
Identities = 67/205 (32%), Positives = 85/205 (41%), Gaps = 19/205 (9%)
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG--VDYCNM-GHSCDEN 336
AEC C G R + CP LP + P G VD C M H C +
Sbjct: 2322 AECCCGGGRGWGPRCE---LCP-LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AH 2376
Query: 337 ATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N + C C G+ D TC D+DEC + C C N G ++C
Sbjct: 2377 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP----KPC--TFLCKNTKGSFLCS 2430
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C GY +D C ++DEC H C +C NT G++TCRC G+ C DE
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDNDE 2488
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
C+ C C N G FRCEC
Sbjct: 2489 CSAQPGPCGAHGHCHNTPGSFRCEC 2513
Score = 99 bits (238), Expect = 2e-20
Identities = 56/161 (34%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSN 381
+D C + N C+N + C+C GF + L C+DVDEC G C N
Sbjct: 1722 IDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC----GSRESPCQQN 1777
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDG 440
C+N+ G Y C+C GY CV +EC + C H D C +T GSY C C G
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGD--CMDTEGSYMCLCHRG 1835
Query: 441 YE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
++ D CM +DEC C + C NI G + C CF
Sbjct: 1836 FQASADQTLCMDIDECDR--QPCGNGT-CKNIIGSYNCLCF 1873
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/159 (35%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNT 382
+D C + N C+ + Y C+CN G+ D C DVDEC + HG
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD------ 462
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN+ G Y C+C G+ + CV+VDEC + CH C NT GS+ C C G+
Sbjct: 463 -CVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAGF 520
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E DG C+ +EC S C + C+N DG F C C
Sbjct: 521 ELSPDGKNCVDHNECAT-STMCVNGV-CLNEDGSFSCLC 557
Score = 95.5 bits (227), Expect = 5e-19
Identities = 70/220 (31%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 265 GNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV 324
G L E R K+ EC N Q V+ A C P F+ + C
Sbjct: 2434 GYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGA---FTCRCPPGFTQHHQACF---DN 2486
Query: 325 DYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
D C+ C + C N + C+C+QGF G C+DV+EC H C
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGP-----HRCQHG 2541
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N +GGY C C G+T+ ++ CV+ +EC + C A C NT G + C C G
Sbjct: 2542 --CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC-GSASCRNTLGGFRCVCPSG 2598
Query: 441 YEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++ D C VDEC C +S C N GGF C C
Sbjct: 2599 FDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGC 2636
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/178 (31%), Positives = 81/178 (45%), Gaps = 13/178 (7%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQ 362
C+ P F+ C VD C S C +NA C+N+ Y CKC +G++ G C
Sbjct: 1746 CECPAGFNY-NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACV 1804
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
+EC+E + C S+ C++ G Y+C C G+ D+ C+++DEC+ G
Sbjct: 1805 GRNECREIPNV----C-SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG-- 1857
Query: 422 ADAVCTNTPGSYTCRCRDGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C N GSY C C G+ C+ DECT C+N G F C C
Sbjct: 1858 -NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLC 1914
Score = 91.1 bits (216), Expect = 1e-17
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGDGLTCQDVDECQEAGGLHGH 376
C +D C+ C N TC N+ Y C C GF GD C D DEC L G
Sbjct: 1845 CMDIDECDR-QPCG-NGTCKNIIGSYNCLCFPGFVVTHNGD---CVDFDECTT---LVGQ 1896
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N G + C C G+ D NCV+ +EC C C N GS+ C
Sbjct: 1897 VCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPGTCQNLEGSFRC 1954
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ C+ +DEC+E + C C N G F+C C
Sbjct: 1955 ICPPGFQVQSDHCIDIDECSEEPNLCLFGT-CTNSPGSFQCLC 1996
Score = 90.2 bits (214), Expect = 2e-17
Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHH 377
C +D C + TC+N + C+C G++ + C DVDEC L
Sbjct: 1026 CTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLL---- 1081
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C T C N G Y CQC G+ K C ++DEC + G C N G++ C
Sbjct: 1082 CRGGT-CTNTDGSYKCQCPPGHELTAKGTACEDIDEC-SLSDGLCPHGQCVNVIGAFQCS 1139
Query: 437 CRDGYEG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C+ ++EC + C C+N +G +RC C
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRCSC 1181
Score = 85.0 bits (201), Expect = 7e-16
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCH 421
D+DEC E + C +N C+N +G + C+C G+ C +VDEC C
Sbjct: 1721 DIDECGEIPAI----C-ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 422 ADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+A C N PGSY C+C GY+ G C+ +EC E + C H C++ +G + C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH-GDCMDTEGSYMCLC 1832
Score = 83.0 bits (196), Expect = 3e-15
Identities = 59/179 (32%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLP----CDPPQQFSVPGECCKFCPGVDY 326
G+ F + ECV + R P C +P C Q F+ G FC D
Sbjct: 1314 GDGFECHDLDECVSQEH-----RCSPRGDCLNVPGSYRCTCRQGFAGDGF---FCEDRDE 1365
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +N C+N Y C+C GF D CQDVDEC + G+ C + C
Sbjct: 1366 CAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-----GNLCAFGS-C 1419
Query: 385 VNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
N+ G + C C GGY + NC +++EC + C + VC NTPGSY C C +E
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVN-C-INGVCINTPGSYLCSCPQDFE 1476
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/165 (35%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ G C DVDEC L+ C N
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC----ALNSLLC-DN 737
Query: 382 TRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C G+ +D C +VDEC + C VC N GSYTC+C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--C-VSGVCRNLAGSYTCKCGPG 794
Query: 441 YEGD--GYTCMHVDECTEGSHTCH---HSARC-VNIDG-GFRCEC 478
D G C+ + T+G TC +RC VN+ G R EC
Sbjct: 795 SRLDPSGTFCL---DSTKG--TCWLKIQESRCEVNLQGASLRSEC 834
Score = 77.8 bits (183), Expect = 1e-13
Identities = 65/234 (27%), Positives = 94/234 (40%), Gaps = 37/234 (15%)
Query: 240 RAEC-KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R +C + L PG C +C N+ HG+ + C+CH G C
Sbjct: 1788 RCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCM 1846
Query: 293 RVDPELACPRLPCDPPQQFSVPGE--CCKF----------CPGVDYCN--MGHSCDENAT 338
+D C R PC ++ G C F C D C +G C
Sbjct: 1847 DIDE---CDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGH 1902
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C+N + C C GF+ DG C D +EC G C T C N+ G + C C
Sbjct: 1903 CLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT----CLPGT-CQNLEGSFRCICP 1957
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTC 448
G+ + +C+++DEC + C CTN+PGS+ C C G+ +G+ C
Sbjct: 1958 PGFQVQSD-HCIDIDECSEEPNLC-LFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 75.8 bits (178), Expect = 5e-13
Identities = 60/207 (28%), Positives = 84/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT +C + GE EC CH G+ C + C C P
Sbjct: 422 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD--CVNIPGTYHCR---CYP 476
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q + + C VD C + C+N + C CN GF+ DG C D +
Sbjct: 477 GFQATPTRQACV---DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHN 533
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ + C+++DEC+ T G +
Sbjct: 534 ECATST-----MC-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ--TPGICVNG 585
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCM 449
CTNT GS+ C+C G DG C+
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCV 612
Score = 73.3 bits (172), Expect = 2e-12
Identities = 44/122 (36%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C+ H C C N Y C C QGF Q VDE + A L C S
Sbjct: 2526 CEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGS 2581
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N +GG+ C C G+ C +VDEC G C C NTPG + C C
Sbjct: 2582 AS-CRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGCPQ 2638
Query: 440 GY 441
GY
Sbjct: 2639 GY 2640
Score = 72.5 bits (170), Expect = 4e-12
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 35/190 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGG 372
G K C VD C + +N C N Y+C C GF D C+DVDEC +
Sbjct: 716 GASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSS-- 773
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD----------KFNC---VEVDECEGNTHG 419
C S C N+ G Y C+C G +R D K C ++ CE N G
Sbjct: 774 ----PCVSGV-CRNLAGSYTCKC-GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQG 827
Query: 420 CHADAVCTNTPGS---YTCR-------CRDGY-EGDGYTCMHVDECTEGSHTCHHSARCV 468
+ C T G+ C C G+ G TC V+EC C + RCV
Sbjct: 828 ASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCV 886
Query: 469 NIDGGFRCEC 478
N G FRCEC
Sbjct: 887 NTAGSFRCEC 896
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 11/125 (8%)
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNV 387
G+ C+ + C +GFQ + +T +D+DECQE GL C CVN
Sbjct: 1528 GNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL----CQGGD-CVNT 1582
Query: 388 VGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGD 444
G + C+C GY + C ++DEC ++ C C NT G+YTC C Y
Sbjct: 1583 FGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYNTLGNYTCVCPAEYLQVNG 1641
Query: 445 GYTCM 449
G CM
Sbjct: 1642 GNNCM 1646
Score = 65.7 bits (153), Expect = 5e-10
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C++ C N Y C C G+ + DG C+DVDEC + C
Sbjct: 2164 CEDIDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ----QDC 2218
Query: 379 HSN-TRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC 435
H+ C N++G + C C G C + +EC C + C NT GS+ C
Sbjct: 2219 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFRC 2277
Query: 436 RCRDGYE 442
C +G++
Sbjct: 2278 DCDEGFQ 2284
Score = 59.7 bits (138), Expect = 3e-08
Identities = 31/71 (43%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCV 468
+D C T+ C + C TP SY C C GY D C+ VDECT S CHH CV
Sbjct: 409 IDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGD-CV 464
Query: 469 NIDGGFRCECF 479
NI G + C C+
Sbjct: 465 NIPGTYHCRCY 475
Score = 56.8 bits (131), Expect = 2e-07
Identities = 65/229 (28%), Positives = 84/229 (36%), Gaps = 39/229 (17%)
Query: 278 ECA-ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA +C +G C D +C C P + G +C +D C C N
Sbjct: 534 ECATSTMCVNG--VCLNEDGSFSCL---CKPGFLLAPGGH---YCMDIDECQTPGIC-VN 584
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDV---DECQ---EAGG----LHGHHCHSNTRC 384
C N + C+C G DG C D C E G G S C
Sbjct: 585 GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 385 VNVVGGY--VCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTPG 431
N G+ CQ C + + + C +++EC + C A+ VC N G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVC-ANGVCENLRG 703
Query: 432 SYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SY C C GYE G C VDEC S C + C N G + C C
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLC-DNGWCQNSPGSYSCSC 751
Score = 55.6 bits (128), Expect = 5e-07
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQ 362
C PQ F+ + + C + C + +A+C N + C C GF D CQ
Sbjct: 2551 CSCPQGFTQHSQWAQ-CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2609
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
DVDEC G G +S C N GG++C C GY R + +CV
Sbjct: 2610 DVDEC---AGRRGPCSYS---CANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 54.4 bits (125), Expect = 1e-06
Identities = 67/245 (27%), Positives = 88/245 (35%), Gaps = 41/245 (16%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSC- 333
CVC+ G CT VD E A L CD + PG C PG + C
Sbjct: 707 CVCNLGYEAGASGKDCTDVD-ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765
Query: 334 --DE-------NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN- 381
DE + C NL YTCKC G + D G C D + + C N
Sbjct: 766 DVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNL 825
Query: 382 ------TRCVNVVG---GYVCQ-------CLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
+ C +G G C+ C G+ R C +V+ECE C +
Sbjct: 826 QGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGR 884
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC-VNIDGGFRCECFTENCE 484
C NT GS+ C C +G D + VD E C V + G +R + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCC--CS 942
Query: 485 LSCSW 489
+ W
Sbjct: 943 IGAVW 947
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 35/213 (16%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-- 357
C R DP C V+ C N C+N + C+C +G D
Sbjct: 846 CERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 905
Query: 358 GLTCQDV-----------DECQ--------------EAGGLHGHHCHSNTRCVNVVGGYV 392
G C DV DEC G + G C + ++ +
Sbjct: 906 GRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASL 965
Query: 393 CQCLGGYTRKDKFN----CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-- 446
C G+ +D + +V+EC+ C C NT GS+ C C G+ D
Sbjct: 966 CPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC C CVN G F CECF
Sbjct: 1025 NCTDIDECRISPDLCGQGT-CVNTPGSFECECF 1056
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/225 (28%), Positives = 82/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGVDYCNM 329
G RF C G QC AC C P + G C GV +
Sbjct: 61 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSC-GV---SR 116
Query: 330 GHSCDENATCMNLNT--KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
G C + +CMN T +C C +G+ G + Q + C + G +G C RC V
Sbjct: 117 GSGC--SVSCMNGGTCRGASCLCQKGYTGT-VCGQPI--C-DRGCHNGGRCIGPNRCACV 170
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHAD-AVCTNTPG---SYTCR------- 436
G QC Y F V + C+ G A+C T G C
Sbjct: 171 YGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 230
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + +T C VDEC C + CVN+ G F C C
Sbjct: 231 PCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRC 274
Score = 49.2 bits (112), Expect = 5e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ C C GY +T C +DEC+ S C
Sbjct: 1563 DIDECQELPGLCQGGD-CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGT 1620
Query: 467 CVNIDGGFRCECFTENCELS 486
C N G + C C E +++
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVN 1640
Score = 48.4 bits (110), Expect = 8e-05
Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 23/226 (10%)
Query: 184 KLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEIT-CRPV-ECDRA 241
KL A + R E + C + +G+ + C+R + T C + ECDR
Sbjct: 1796 KLSPGGACVGRNECREIPNVCSHGDCMDTEGS-YMCLCHRGFQASADQTLCMDIDECDRQ 1854
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECV---CHDGNMQCTRVDPEL 298
C N CL C + +G+ EC V C G+ C
Sbjct: 1855 PCGNGTCKNIIGSYNCL--CFPGFVVTHNGDCVDFDECTTLVGQVCRFGH--CLNTAGSF 1910
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
C C + + G K C + C ++ +C TC NL + C C GFQ
Sbjct: 1911 HCL---CQDGFELTADG---KNCVDTNECLSLAGTCLPG-TCQNLEGSFRCICPPGFQVQ 1963
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C D+DEC E L C T C N G + C C G+ D
Sbjct: 1964 SDHCIDIDECSEEPNL----CLFGT-CTNSPGSFQCLCPPGFVLSD 2004
Score = 44.0 bits (99), Expect = 0.002
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ T C+D+DEC H C
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDEC----STHSSICGPG 1619
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N +G Y C C Y + NC+++
Sbjct: 1620 T-CYNTLGNYTCVCPAEYLQVNGGNNCMDM 1648
Score = 42.3 bits (95), Expect = 0.005
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 350 CNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C +GF + T CQDVDECQ GL C + CVN+VG + C+C G+ D
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGL----CQGGS-CVNMVGSFHCRCPVGHRLSD 282
Score = 33.1 bits (72), Expect = 3.2
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C +VDEC+ C + C N GS+ CRC G+
Sbjct: 245 CQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGH 278
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 142 bits (344), Expect = 3e-33
Identities = 94/302 (31%), Positives = 126/302 (41%), Gaps = 20/302 (6%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C + + G D + +C C G E+T + C D EC
Sbjct: 1058 GYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDEC 1117
Query: 244 K-NPVLHP-GECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELAC 300
+ L P G+C QC +R + EC +G ++ E
Sbjct: 1118 SLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GS 1176
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DG 358
R C G C VD C + C N+ + C C GF D
Sbjct: 1177 YRCSCGQGYSLMPDGRACA---DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDM 1233
Query: 359 LTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGN 416
TC DVDEC L+ H C H + C N G +VC C GY RK C +VDECE
Sbjct: 1234 RTCVDVDECD----LNPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 417 THGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
H C + A C N PGS++CRC G+ GDG+ C +DEC H C C+N+ G +RC
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC 1347
Query: 477 EC 478
C
Sbjct: 1348 TC 1349
Score = 140 bits (339), Expect = 1e-32
Identities = 65/160 (40%), Positives = 85/160 (53%), Gaps = 8/160 (5%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHC 378
C VD C++ + C N + C C G+ G T C DVDEC E GG H+C
Sbjct: 1236 CVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC-EVGG---HNC 1291
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ C+N+ G + C+CL G+ D F C ++DEC H C C N PGSY C CR
Sbjct: 1292 DSHASCLNIPGSFSCRCLPGWVG-DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+ C DEC E C + +C+N GG+RCEC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCEC 1389
Score = 124 bits (300), Expect = 8e-28
Identities = 63/166 (37%), Positives = 80/166 (48%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C VD C TC N + Y C+C G + G C+D+DEC + GL H
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH 1126
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+CVNV+G + C C G+ + D+ CV+++EC GC D C NT GSY C
Sbjct: 1127 G-----QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRC 1179
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C GY DG C VDEC E C C N+ GG RC C+
Sbjct: 1180 SCGQGYSLMPDGRACADVDECEENPRVCDQG-HCTNMPGGHRCLCY 1224
Score = 115 bits (277), Expect = 5e-25
Identities = 68/178 (38%), Positives = 91/178 (51%), Gaps = 16/178 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C + H C C+N+ Y C C QGF GDG C+D DEC E L C
Sbjct: 1319 CHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL----C- 1373
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
N +C+N GGY C+C G+ +D C +VDEC +GN C A C N PG + C C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL--C-AFGSCENLPGMFRCIC 1430
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRV 493
GYE D G C ++EC + + C + C+N G + C C ++ EL+ S G V
Sbjct: 1431 NGGYELDRGGGNCTDINECADPVN-CINGV-CINTPGSYLCSC-PQDFELNPSGVGCV 1485
Score = 114 bits (275), Expect = 8e-25
Identities = 75/209 (35%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 278 ECAEC--VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE VC +G C D C C P +S+ C D C++GH C +
Sbjct: 2087 ECAENPGVCTNG--VCVNTDGSFRCE---C--PFGYSLDFTGIN-CVDTDECSVGHPCGQ 2138
Query: 336 NATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
TC N+ + C C GF+ G +TC+D+DEC L CH N G Y+C
Sbjct: 2139 G-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCH------NTEGSYLCT 2191
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAV-CTNTPGSYTCRCRDGYE---GDGYTCM 449
C GYT R+D C +VDEC CHA + C N G++ C C G G G C
Sbjct: 2192 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC C + RCVN G FRC+C
Sbjct: 2252 DDNECHAQPDLCVNG-RCVNTAGSFRCDC 2279
Score = 111 bits (267), Expect = 7e-24
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 14/144 (9%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C C +G+ + DG TC+D+DEC H+C CVN VG + C+C
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS----RQHNCQF--LCVNTVGAFTCRCP 2473
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDEC 454
G+T+ + C + DEC C A C NTPGS+ C C G+ G+ C V+EC
Sbjct: 2474 PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
+G H C H C N GG+RC C
Sbjct: 2533 -DGPHRCQHG--CQNQLGGYRCSC 2553
Score = 111 bits (266), Expect = 1e-23
Identities = 59/160 (36%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC GH C
Sbjct: 2085 VNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-----GHPCGQG 2139
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+GG+ C C G+ C ++DEC N C C NT GSY C C GY
Sbjct: 2140 T-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGY 2196
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
DG C VDEC +G CH C N+ G F C C
Sbjct: 2197 TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Score = 108 bits (260), Expect = 5e-23
Identities = 94/311 (30%), Positives = 125/311 (40%), Gaps = 39/311 (12%)
Query: 193 SRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD------RAECKNP 246
S E+C+ +C + G G T D N C G C C R EC
Sbjct: 844 SPCERCEIDPAC-ARGFARMTGVTCD-DVNECESFPG--VCPNGRCVNTAGSFRCECPEG 899
Query: 247 VLHPGE---CCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDG---NMQCTRV-DPEL 298
++ C L C L + E G K + C C G ++C DPE
Sbjct: 900 LMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPES 959
Query: 299 A-----CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
CPR + F + G F V+ C + + TC N + C C G
Sbjct: 960 LEFASLCPRGLGFASRDF-LSGR--PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGG 1016
Query: 354 FQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF--NCVE 409
F D C D+DEC+ + L C T CVN G + C+C GY NC++
Sbjct: 1017 FALDAQERNCTDIDECRISPDL----CGQGT-CVNTPGSFECECFPGYESGFMLMKNCMD 1071
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARC 467
VDEC + C CTNT GSY C+C G+E G C +DEC+ C H +C
Sbjct: 1072 VDECARDPLLCRG-GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQC 1129
Query: 468 VNIDGGFRCEC 478
VN+ G F+C C
Sbjct: 1130 VNVIGAFQCSC 1140
Score = 107 bits (256), Expect = 2e-22
Identities = 69/183 (37%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-- 359
R C+ V GEC VD C C + C+N+ Y C+C GFQ
Sbjct: 432 RCECNVGYTQDVRGECID----VDECTSS-PC-HHGDCVNIPGTYHCRCYPGFQATPTRQ 485
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTH 418
C DVDEC +GGL CH RCVN G + C C G+ D NCV+ +EC +T
Sbjct: 486 ACVDVDECIVSGGL----CHLG-RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 419 GCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
C + VC N GS++C C+ G+ G+ CM +DEC T G H C N +G FR
Sbjct: 541 -C-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH---CTNTEGSFR 595
Query: 476 CEC 478
C+C
Sbjct: 596 CQC 598
Score = 103 bits (247), Expect = 2e-21
Identities = 67/205 (32%), Positives = 85/205 (41%), Gaps = 19/205 (9%)
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG--VDYCNM-GHSCDEN 336
AEC C G R + CP LP + P G VD C M H C +
Sbjct: 2322 AECCCGGGRGWGPRCE---LCP-LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AH 2376
Query: 337 ATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N + C C G+ D TC D+DEC + C C N G ++C
Sbjct: 2377 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP----KPC--TFLCKNTKGSFLCS 2430
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C GY +D C ++DEC H C +C NT G++TCRC G+ C DE
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDNDE 2488
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
C+ C C N G FRCEC
Sbjct: 2489 CSAQPGPCGAHGHCHNTPGSFRCEC 2513
Score = 99 bits (238), Expect = 2e-20
Identities = 56/161 (34%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSN 381
+D C + N C+N + C+C GF + L C+DVDEC G C N
Sbjct: 1722 IDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC----GSRESPCQQN 1777
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDG 440
C+N+ G Y C+C GY CV +EC + C H D C +T GSY C C G
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGD--CMDTEGSYMCLCHRG 1835
Query: 441 YE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
++ D CM +DEC C + C NI G + C CF
Sbjct: 1836 FQASADQTLCMDIDECDR--QPCGNGT-CKNIIGSYNCLCF 1873
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/159 (35%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNT 382
+D C + N C+ + Y C+CN G+ D C DVDEC + HG
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD------ 462
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN+ G Y C+C G+ + CV+VDEC + CH C NT GS+ C C G+
Sbjct: 463 -CVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAGF 520
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E DG C+ +EC S C + C+N DG F C C
Sbjct: 521 ELSPDGKNCVDHNECAT-STMCVNGV-CLNEDGSFSCLC 557
Score = 95.5 bits (227), Expect = 5e-19
Identities = 70/220 (31%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 265 GNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV 324
G L E R K+ EC N Q V+ A C P F+ + C
Sbjct: 2434 GYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGA---FTCRCPPGFTQHHQACF---DN 2486
Query: 325 DYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
D C+ C + C N + C+C+QGF G C+DV+EC H C
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGP-----HRCQHG 2541
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N +GGY C C G+T+ ++ CV+ +EC + C A C NT G + C C G
Sbjct: 2542 --CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC-GSASCRNTLGGFRCVCPSG 2598
Query: 441 YEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++ D C VDEC C +S C N GGF C C
Sbjct: 2599 FDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGC 2636
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/178 (31%), Positives = 81/178 (45%), Gaps = 13/178 (7%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQ 362
C+ P F+ C VD C S C +NA C+N+ Y CKC +G++ G C
Sbjct: 1746 CECPAGFNY-NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACV 1804
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
+EC+E + C S+ C++ G Y+C C G+ D+ C+++DEC+ G
Sbjct: 1805 GRNECREIPNV----C-SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG-- 1857
Query: 422 ADAVCTNTPGSYTCRCRDGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C N GSY C C G+ C+ DECT C+N G F C C
Sbjct: 1858 -NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLC 1914
Score = 91.1 bits (216), Expect = 1e-17
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGDGLTCQDVDECQEAGGLHGH 376
C +D C+ C N TC N+ Y C C GF GD C D DEC L G
Sbjct: 1845 CMDIDECDR-QPCG-NGTCKNIIGSYNCLCFPGFVVTHNGD---CVDFDECTT---LVGQ 1896
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N G + C C G+ D NCV+ +EC C C N GS+ C
Sbjct: 1897 VCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPGTCQNLEGSFRC 1954
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ C+ +DEC+E + C C N G F+C C
Sbjct: 1955 ICPPGFQVQSDHCIDIDECSEEPNLCLFGT-CTNSPGSFQCLC 1996
Score = 90.2 bits (214), Expect = 2e-17
Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHH 377
C +D C + TC+N + C+C G++ + C DVDEC L
Sbjct: 1026 CTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLL---- 1081
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C T C N G Y CQC G+ K C ++DEC + G C N G++ C
Sbjct: 1082 CRGGT-CTNTDGSYKCQCPPGHELTAKGTACEDIDEC-SLSDGLCPHGQCVNVIGAFQCS 1139
Query: 437 CRDGYEG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C+ ++EC + C C+N +G +RC C
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRCSC 1181
Score = 85.0 bits (201), Expect = 7e-16
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCH 421
D+DEC E + C +N C+N +G + C+C G+ C +VDEC C
Sbjct: 1721 DIDECGEIPAI----C-ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 422 ADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+A C N PGSY C+C GY+ G C+ +EC E + C H C++ +G + C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH-GDCMDTEGSYMCLC 1832
Score = 83.0 bits (196), Expect = 3e-15
Identities = 59/179 (32%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLP----CDPPQQFSVPGECCKFCPGVDY 326
G+ F + ECV + R P C +P C Q F+ G FC D
Sbjct: 1314 GDGFECHDLDECVSQEH-----RCSPRGDCLNVPGSYRCTCRQGFAGDGF---FCEDRDE 1365
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +N C+N Y C+C GF D CQDVDEC + G+ C + C
Sbjct: 1366 CAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-----GNLCAFGS-C 1419
Query: 385 VNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
N+ G + C C GGY + NC +++EC + C + VC NTPGSY C C +E
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVN-C-INGVCINTPGSYLCSCPQDFE 1476
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/165 (35%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ G C DVDEC L+ C N
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC----ALNSLLC-DN 737
Query: 382 TRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C G+ +D C +VDEC + C VC N GSYTC+C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--C-VSGVCRNLAGSYTCKCGPG 794
Query: 441 YEGD--GYTCMHVDECTEGSHTCH---HSARC-VNIDG-GFRCEC 478
D G C+ + T+G TC +RC VN+ G R EC
Sbjct: 795 SRLDPSGTFCL---DSTKG--TCWLKIQESRCEVNLQGASLRSEC 834
Score = 77.8 bits (183), Expect = 1e-13
Identities = 65/234 (27%), Positives = 94/234 (40%), Gaps = 37/234 (15%)
Query: 240 RAEC-KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R +C + L PG C +C N+ HG+ + C+CH G C
Sbjct: 1788 RCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCM 1846
Query: 293 RVDPELACPRLPCDPPQQFSVPGE--CCKF----------CPGVDYCN--MGHSCDENAT 338
+D C R PC ++ G C F C D C +G C
Sbjct: 1847 DIDE---CDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGH 1902
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C+N + C C GF+ DG C D +EC G C T C N+ G + C C
Sbjct: 1903 CLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT----CLPGT-CQNLEGSFRCICP 1957
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTC 448
G+ + +C+++DEC + C CTN+PGS+ C C G+ +G+ C
Sbjct: 1958 PGFQVQSD-HCIDIDECSEEPNLC-LFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 75.8 bits (178), Expect = 5e-13
Identities = 60/207 (28%), Positives = 84/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT +C + GE EC CH G+ C + C C P
Sbjct: 422 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD--CVNIPGTYHCR---CYP 476
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q + + C VD C + C+N + C CN GF+ DG C D +
Sbjct: 477 GFQATPTRQACV---DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHN 533
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ + C+++DEC+ T G +
Sbjct: 534 ECATST-----MC-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ--TPGICVNG 585
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCM 449
CTNT GS+ C+C G DG C+
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCV 612
Score = 73.3 bits (172), Expect = 2e-12
Identities = 44/122 (36%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C+ H C C N Y C C QGF Q VDE + A L C S
Sbjct: 2526 CEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGS 2581
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N +GG+ C C G+ C +VDEC G C C NTPG + C C
Sbjct: 2582 AS-CRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGCPQ 2638
Query: 440 GY 441
GY
Sbjct: 2639 GY 2640
Score = 72.5 bits (170), Expect = 4e-12
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 35/190 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGG 372
G K C VD C + +N C N Y+C C GF D C+DVDEC +
Sbjct: 716 GASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSS-- 773
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD----------KFNC---VEVDECEGNTHG 419
C S C N+ G Y C+C G +R D K C ++ CE N G
Sbjct: 774 ----PCVSGV-CRNLAGSYTCKC-GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQG 827
Query: 420 CHADAVCTNTPGS---YTCR-------CRDGY-EGDGYTCMHVDECTEGSHTCHHSARCV 468
+ C T G+ C C G+ G TC V+EC C + RCV
Sbjct: 828 ASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCV 886
Query: 469 NIDGGFRCEC 478
N G FRCEC
Sbjct: 887 NTAGSFRCEC 896
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 11/125 (8%)
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNV 387
G+ C+ + C +GFQ + +T +D+DECQE GL C CVN
Sbjct: 1528 GNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL----CQGGD-CVNT 1582
Query: 388 VGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGD 444
G + C+C GY + C ++DEC ++ C C NT G+YTC C Y
Sbjct: 1583 FGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYNTLGNYTCVCPAEYLQVNG 1641
Query: 445 GYTCM 449
G CM
Sbjct: 1642 GNNCM 1646
Score = 65.7 bits (153), Expect = 5e-10
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C++ C N Y C C G+ + DG C+DVDEC + C
Sbjct: 2164 CEDIDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ----QDC 2218
Query: 379 HSN-TRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC 435
H+ C N++G + C C G C + +EC C + C NT GS+ C
Sbjct: 2219 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFRC 2277
Query: 436 RCRDGYE 442
C +G++
Sbjct: 2278 DCDEGFQ 2284
Score = 59.7 bits (138), Expect = 3e-08
Identities = 31/71 (43%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCV 468
+D C T+ C + C TP SY C C GY D C+ VDECT S CHH CV
Sbjct: 409 IDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGD-CV 464
Query: 469 NIDGGFRCECF 479
NI G + C C+
Sbjct: 465 NIPGTYHCRCY 475
Score = 56.8 bits (131), Expect = 2e-07
Identities = 65/229 (28%), Positives = 84/229 (36%), Gaps = 39/229 (17%)
Query: 278 ECA-ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA +C +G C D +C C P + G +C +D C C N
Sbjct: 534 ECATSTMCVNG--VCLNEDGSFSCL---CKPGFLLAPGGH---YCMDIDECQTPGIC-VN 584
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDV---DECQ---EAGG----LHGHHCHSNTRC 384
C N + C+C G DG C D C E G G S C
Sbjct: 585 GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 385 VNVVGGY--VCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTPG 431
N G+ CQ C + + + C +++EC + C A+ VC N G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVC-ANGVCENLRG 703
Query: 432 SYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SY C C GYE G C VDEC S C + C N G + C C
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLC-DNGWCQNSPGSYSCSC 751
Score = 55.6 bits (128), Expect = 5e-07
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQ 362
C PQ F+ + + C + C + +A+C N + C C GF D CQ
Sbjct: 2551 CSCPQGFTQHSQWAQ-CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2609
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
DVDEC G G +S C N GG++C C GY R + +CV
Sbjct: 2610 DVDEC---AGRRGPCSYS---CANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 54.4 bits (125), Expect = 1e-06
Identities = 67/245 (27%), Positives = 88/245 (35%), Gaps = 41/245 (16%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSC- 333
CVC+ G CT VD E A L CD + PG C PG + C
Sbjct: 707 CVCNLGYEAGASGKDCTDVD-ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765
Query: 334 --DE-------NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN- 381
DE + C NL YTCKC G + D G C D + + C N
Sbjct: 766 DVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNL 825
Query: 382 ------TRCVNVVG---GYVCQ-------CLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
+ C +G G C+ C G+ R C +V+ECE C +
Sbjct: 826 QGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGR 884
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC-VNIDGGFRCECFTENCE 484
C NT GS+ C C +G D + VD E C V + G +R + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCC--CS 942
Query: 485 LSCSW 489
+ W
Sbjct: 943 IGAVW 947
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 35/213 (16%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-- 357
C R DP C V+ C N C+N + C+C +G D
Sbjct: 846 CERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 905
Query: 358 GLTCQDV-----------DECQ--------------EAGGLHGHHCHSNTRCVNVVGGYV 392
G C DV DEC G + G C + ++ +
Sbjct: 906 GRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASL 965
Query: 393 CQCLGGYTRKDKFN----CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-- 446
C G+ +D + +V+EC+ C C NT GS+ C C G+ D
Sbjct: 966 CPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC C CVN G F CECF
Sbjct: 1025 NCTDIDECRISPDLCGQGT-CVNTPGSFECECF 1056
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/225 (28%), Positives = 82/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGVDYCNM 329
G RF C G QC AC C P + G C GV +
Sbjct: 61 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSC-GV---SR 116
Query: 330 GHSCDENATCMNLNT--KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
G C + +CMN T +C C +G+ G + Q + C + G +G C RC V
Sbjct: 117 GSGC--SVSCMNGGTCRGASCLCQKGYTGT-VCGQPI--C-DRGCHNGGRCIGPNRCACV 170
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHAD-AVCTNTPG---SYTCR------- 436
G QC Y F V + C+ G A+C T G C
Sbjct: 171 YGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 230
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + +T C VDEC C + CVN+ G F C C
Sbjct: 231 PCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRC 274
Score = 49.2 bits (112), Expect = 5e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ C C GY +T C +DEC+ S C
Sbjct: 1563 DIDECQELPGLCQGGD-CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGT 1620
Query: 467 CVNIDGGFRCECFTENCELS 486
C N G + C C E +++
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVN 1640
Score = 48.4 bits (110), Expect = 8e-05
Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 23/226 (10%)
Query: 184 KLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEIT-CRPV-ECDRA 241
KL A + R E + C + +G+ + C+R + T C + ECDR
Sbjct: 1796 KLSPGGACVGRNECREIPNVCSHGDCMDTEGS-YMCLCHRGFQASADQTLCMDIDECDRQ 1854
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECV---CHDGNMQCTRVDPEL 298
C N CL C + +G+ EC V C G+ C
Sbjct: 1855 PCGNGTCKNIIGSYNCL--CFPGFVVTHNGDCVDFDECTTLVGQVCRFGH--CLNTAGSF 1910
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
C C + + G K C + C ++ +C TC NL + C C GFQ
Sbjct: 1911 HCL---CQDGFELTADG---KNCVDTNECLSLAGTCLPG-TCQNLEGSFRCICPPGFQVQ 1963
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C D+DEC E L C T C N G + C C G+ D
Sbjct: 1964 SDHCIDIDECSEEPNL----CLFGT-CTNSPGSFQCLCPPGFVLSD 2004
Score = 44.0 bits (99), Expect = 0.002
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ T C+D+DEC H C
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDEC----STHSSICGPG 1619
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N +G Y C C Y + NC+++
Sbjct: 1620 T-CYNTLGNYTCVCPAEYLQVNGGNNCMDM 1648
Score = 42.3 bits (95), Expect = 0.005
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 350 CNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C +GF + T CQDVDECQ GL C + CVN+VG + C+C G+ D
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGL----CQGGS-CVNMVGSFHCRCPVGHRLSD 282
Score = 33.1 bits (72), Expect = 3.2
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C +VDEC+ C + C N GS+ CRC G+
Sbjct: 245 CQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGH 278
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 142 bits (344), Expect = 3e-33
Identities = 94/302 (31%), Positives = 126/302 (41%), Gaps = 20/302 (6%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C + + G D + +C C G E+T + C D EC
Sbjct: 1058 GYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDEC 1117
Query: 244 K-NPVLHP-GECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELAC 300
+ L P G+C QC +R + EC +G ++ E
Sbjct: 1118 SLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GS 1176
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DG 358
R C G C VD C + C N+ + C C GF D
Sbjct: 1177 YRCSCGQGYSLMPDGRACA---DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDM 1233
Query: 359 LTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGN 416
TC DVDEC L+ H C H + C N G +VC C GY RK C +VDECE
Sbjct: 1234 RTCVDVDECD----LNPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 417 THGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
H C + A C N PGS++CRC G+ GDG+ C +DEC H C C+N+ G +RC
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC 1347
Query: 477 EC 478
C
Sbjct: 1348 TC 1349
Score = 140 bits (339), Expect = 1e-32
Identities = 65/160 (40%), Positives = 85/160 (53%), Gaps = 8/160 (5%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHC 378
C VD C++ + C N + C C G+ G T C DVDEC E GG H+C
Sbjct: 1236 CVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC-EVGG---HNC 1291
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ C+N+ G + C+CL G+ D F C ++DEC H C C N PGSY C CR
Sbjct: 1292 DSHASCLNIPGSFSCRCLPGWVG-DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+ C DEC E C + +C+N GG+RCEC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCEC 1389
Score = 124 bits (300), Expect = 8e-28
Identities = 63/166 (37%), Positives = 80/166 (48%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C VD C TC N + Y C+C G + G C+D+DEC + GL H
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH 1126
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+CVNV+G + C C G+ + D+ CV+++EC GC D C NT GSY C
Sbjct: 1127 G-----QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRC 1179
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C GY DG C VDEC E C C N+ GG RC C+
Sbjct: 1180 SCGQGYSLMPDGRACADVDECEENPRVCDQG-HCTNMPGGHRCLCY 1224
Score = 115 bits (277), Expect = 5e-25
Identities = 68/178 (38%), Positives = 91/178 (51%), Gaps = 16/178 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C + H C C+N+ Y C C QGF GDG C+D DEC E L C
Sbjct: 1319 CHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL----C- 1373
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
N +C+N GGY C+C G+ +D C +VDEC +GN C A C N PG + C C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL--C-AFGSCENLPGMFRCIC 1430
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRV 493
GYE D G C ++EC + + C + C+N G + C C ++ EL+ S G V
Sbjct: 1431 NGGYELDRGGGNCTDINECADPVN-CINGV-CINTPGSYLCSC-PQDFELNPSGVGCV 1485
Score = 114 bits (275), Expect = 8e-25
Identities = 75/209 (35%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 278 ECAEC--VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE VC +G C D C C P +S+ C D C++GH C +
Sbjct: 2087 ECAENPGVCTNG--VCVNTDGSFRCE---C--PFGYSLDFTGIN-CVDTDECSVGHPCGQ 2138
Query: 336 NATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
TC N+ + C C GF+ G +TC+D+DEC L CH N G Y+C
Sbjct: 2139 G-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCH------NTEGSYLCT 2191
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAV-CTNTPGSYTCRCRDGYE---GDGYTCM 449
C GYT R+D C +VDEC CHA + C N G++ C C G G G C
Sbjct: 2192 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC C + RCVN G FRC+C
Sbjct: 2252 DDNECHAQPDLCVNG-RCVNTAGSFRCDC 2279
Score = 111 bits (267), Expect = 7e-24
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 14/144 (9%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C C +G+ + DG TC+D+DEC H+C CVN VG + C+C
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS----RQHNCQF--LCVNTVGAFTCRCP 2473
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDEC 454
G+T+ + C + DEC C A C NTPGS+ C C G+ G+ C V+EC
Sbjct: 2474 PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
+G H C H C N GG+RC C
Sbjct: 2533 -DGPHRCQHG--CQNQLGGYRCSC 2553
Score = 111 bits (266), Expect = 1e-23
Identities = 59/160 (36%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC GH C
Sbjct: 2085 VNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-----GHPCGQG 2139
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+GG+ C C G+ C ++DEC N C C NT GSY C C GY
Sbjct: 2140 T-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGY 2196
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
DG C VDEC +G CH C N+ G F C C
Sbjct: 2197 TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Score = 108 bits (260), Expect = 5e-23
Identities = 94/311 (30%), Positives = 125/311 (40%), Gaps = 39/311 (12%)
Query: 193 SRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD------RAECKNP 246
S E+C+ +C + G G T D N C G C C R EC
Sbjct: 844 SPCERCEIDPAC-ARGFARMTGVTCD-DVNECESFPG--VCPNGRCVNTAGSFRCECPEG 899
Query: 247 VLHPGE---CCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDG---NMQCTRV-DPEL 298
++ C L C L + E G K + C C G ++C DPE
Sbjct: 900 LMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDFCCCSIGAVWGVECEACPDPES 959
Query: 299 A-----CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
CPR + F + G F V+ C + + TC N + C C G
Sbjct: 960 LEFASLCPRGLGFASRDF-LSGR--PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGG 1016
Query: 354 FQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF--NCVE 409
F D C D+DEC+ + L C T CVN G + C+C GY NC++
Sbjct: 1017 FALDAQERNCTDIDECRISPDL----CGQGT-CVNTPGSFECECFPGYESGFMLMKNCMD 1071
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARC 467
VDEC + C CTNT GSY C+C G+E G C +DEC+ C H +C
Sbjct: 1072 VDECARDPLLCRG-GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQC 1129
Query: 468 VNIDGGFRCEC 478
VN+ G F+C C
Sbjct: 1130 VNVIGAFQCSC 1140
Score = 107 bits (256), Expect = 2e-22
Identities = 69/183 (37%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-- 359
R C+ V GEC VD C C + C+N+ Y C+C GFQ
Sbjct: 432 RCECNVGYTQDVRGECID----VDECTSS-PC-HHGDCVNIPGTYHCRCYPGFQATPTRQ 485
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTH 418
C DVDEC +GGL CH RCVN G + C C G+ D NCV+ +EC +T
Sbjct: 486 ACVDVDECIVSGGL----CHLG-RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 419 GCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
C + VC N GS++C C+ G+ G+ CM +DEC T G H C N +G FR
Sbjct: 541 -C-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH---CTNTEGSFR 595
Query: 476 CEC 478
C+C
Sbjct: 596 CQC 598
Score = 103 bits (247), Expect = 2e-21
Identities = 67/205 (32%), Positives = 85/205 (41%), Gaps = 19/205 (9%)
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG--VDYCNM-GHSCDEN 336
AEC C G R + CP LP + P G VD C M H C +
Sbjct: 2322 AECCCGGGRGWGPRCE---LCP-LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AH 2376
Query: 337 ATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N + C C G+ D TC D+DEC + C C N G ++C
Sbjct: 2377 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP----KPC--TFLCKNTKGSFLCS 2430
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C GY +D C ++DEC H C +C NT G++TCRC G+ C DE
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDNDE 2488
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
C+ C C N G FRCEC
Sbjct: 2489 CSAQPGPCGAHGHCHNTPGSFRCEC 2513
Score = 99 bits (238), Expect = 2e-20
Identities = 56/161 (34%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSN 381
+D C + N C+N + C+C GF + L C+DVDEC G C N
Sbjct: 1722 IDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC----GSRESPCQQN 1777
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDG 440
C+N+ G Y C+C GY CV +EC + C H D C +T GSY C C G
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGD--CMDTEGSYMCLCHRG 1835
Query: 441 YE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
++ D CM +DEC C + C NI G + C CF
Sbjct: 1836 FQASADQTLCMDIDECDR--QPCGNGT-CKNIIGSYNCLCF 1873
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/159 (35%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNT 382
+D C + N C+ + Y C+CN G+ D C DVDEC + HG
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD------ 462
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN+ G Y C+C G+ + CV+VDEC + CH C NT GS+ C C G+
Sbjct: 463 -CVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAGF 520
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E DG C+ +EC S C + C+N DG F C C
Sbjct: 521 ELSPDGKNCVDHNECAT-STMCVNGV-CLNEDGSFSCLC 557
Score = 95.5 bits (227), Expect = 5e-19
Identities = 70/220 (31%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 265 GNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV 324
G L E R K+ EC N Q V+ A C P F+ + C
Sbjct: 2434 GYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGA---FTCRCPPGFTQHHQACF---DN 2486
Query: 325 DYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
D C+ C + C N + C+C+QGF G C+DV+EC H C
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGP-----HRCQHG 2541
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N +GGY C C G+T+ ++ CV+ +EC + C A C NT G + C C G
Sbjct: 2542 --CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC-GSASCRNTLGGFRCVCPSG 2598
Query: 441 YEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++ D C VDEC C +S C N GGF C C
Sbjct: 2599 FDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGC 2636
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/178 (31%), Positives = 81/178 (45%), Gaps = 13/178 (7%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQ 362
C+ P F+ C VD C S C +NA C+N+ Y CKC +G++ G C
Sbjct: 1746 CECPAGFNY-NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACV 1804
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
+EC+E + C S+ C++ G Y+C C G+ D+ C+++DEC+ G
Sbjct: 1805 GRNECREIPNV----C-SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG-- 1857
Query: 422 ADAVCTNTPGSYTCRCRDGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C N GSY C C G+ C+ DECT C+N G F C C
Sbjct: 1858 -NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLC 1914
Score = 91.1 bits (216), Expect = 1e-17
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGDGLTCQDVDECQEAGGLHGH 376
C +D C+ C N TC N+ Y C C GF GD C D DEC L G
Sbjct: 1845 CMDIDECDR-QPCG-NGTCKNIIGSYNCLCFPGFVVTHNGD---CVDFDECTT---LVGQ 1896
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N G + C C G+ D NCV+ +EC C C N GS+ C
Sbjct: 1897 VCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPGTCQNLEGSFRC 1954
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ C+ +DEC+E + C C N G F+C C
Sbjct: 1955 ICPPGFQVQSDHCIDIDECSEEPNLCLFGT-CTNSPGSFQCLC 1996
Score = 90.2 bits (214), Expect = 2e-17
Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHH 377
C +D C + TC+N + C+C G++ + C DVDEC L
Sbjct: 1026 CTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLL---- 1081
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C T C N G Y CQC G+ K C ++DEC + G C N G++ C
Sbjct: 1082 CRGGT-CTNTDGSYKCQCPPGHELTAKGTACEDIDEC-SLSDGLCPHGQCVNVIGAFQCS 1139
Query: 437 CRDGYEG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C+ ++EC + C C+N +G +RC C
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRCSC 1181
Score = 85.0 bits (201), Expect = 7e-16
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCH 421
D+DEC E + C +N C+N +G + C+C G+ C +VDEC C
Sbjct: 1721 DIDECGEIPAI----C-ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 422 ADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+A C N PGSY C+C GY+ G C+ +EC E + C H C++ +G + C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH-GDCMDTEGSYMCLC 1832
Score = 83.0 bits (196), Expect = 3e-15
Identities = 59/179 (32%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLP----CDPPQQFSVPGECCKFCPGVDY 326
G+ F + ECV + R P C +P C Q F+ G FC D
Sbjct: 1314 GDGFECHDLDECVSQEH-----RCSPRGDCLNVPGSYRCTCRQGFAGDGF---FCEDRDE 1365
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +N C+N Y C+C GF D CQDVDEC + G+ C + C
Sbjct: 1366 CAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-----GNLCAFGS-C 1419
Query: 385 VNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
N+ G + C C GGY + NC +++EC + C + VC NTPGSY C C +E
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVN-C-INGVCINTPGSYLCSCPQDFE 1476
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/165 (35%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ G C DVDEC L+ C N
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC----ALNSLLC-DN 737
Query: 382 TRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C G+ +D C +VDEC + C VC N GSYTC+C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--C-VSGVCRNLAGSYTCKCGPG 794
Query: 441 YEGD--GYTCMHVDECTEGSHTCH---HSARC-VNIDG-GFRCEC 478
D G C+ + T+G TC +RC VN+ G R EC
Sbjct: 795 SRLDPSGTFCL---DSTKG--TCWLKIQESRCEVNLQGASLRSEC 834
Score = 77.8 bits (183), Expect = 1e-13
Identities = 65/234 (27%), Positives = 94/234 (40%), Gaps = 37/234 (15%)
Query: 240 RAEC-KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R +C + L PG C +C N+ HG+ + C+CH G C
Sbjct: 1788 RCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCM 1846
Query: 293 RVDPELACPRLPCDPPQQFSVPGE--CCKF----------CPGVDYCN--MGHSCDENAT 338
+D C R PC ++ G C F C D C +G C
Sbjct: 1847 DIDE---CDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGH 1902
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C+N + C C GF+ DG C D +EC G C T C N+ G + C C
Sbjct: 1903 CLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT----CLPGT-CQNLEGSFRCICP 1957
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTC 448
G+ + +C+++DEC + C CTN+PGS+ C C G+ +G+ C
Sbjct: 1958 PGFQVQSD-HCIDIDECSEEPNLC-LFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 75.8 bits (178), Expect = 5e-13
Identities = 60/207 (28%), Positives = 84/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT +C + GE EC CH G+ C + C C P
Sbjct: 422 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD--CVNIPGTYHCR---CYP 476
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q + + C VD C + C+N + C CN GF+ DG C D +
Sbjct: 477 GFQATPTRQACV---DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHN 533
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ + C+++DEC+ T G +
Sbjct: 534 ECATST-----MC-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ--TPGICVNG 585
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCM 449
CTNT GS+ C+C G DG C+
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCV 612
Score = 73.3 bits (172), Expect = 2e-12
Identities = 44/122 (36%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C+ H C C N Y C C QGF Q VDE + A L C S
Sbjct: 2526 CEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGS 2581
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N +GG+ C C G+ C +VDEC G C C NTPG + C C
Sbjct: 2582 AS-CRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGCPQ 2638
Query: 440 GY 441
GY
Sbjct: 2639 GY 2640
Score = 72.5 bits (170), Expect = 4e-12
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 35/190 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGG 372
G K C VD C + +N C N Y+C C GF D C+DVDEC +
Sbjct: 716 GASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSS-- 773
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD----------KFNC---VEVDECEGNTHG 419
C S C N+ G Y C+C G +R D K C ++ CE N G
Sbjct: 774 ----PCVSGV-CRNLAGSYTCKC-GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQG 827
Query: 420 CHADAVCTNTPGS---YTCR-------CRDGY-EGDGYTCMHVDECTEGSHTCHHSARCV 468
+ C T G+ C C G+ G TC V+EC C + RCV
Sbjct: 828 ASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCV 886
Query: 469 NIDGGFRCEC 478
N G FRCEC
Sbjct: 887 NTAGSFRCEC 896
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 11/125 (8%)
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNV 387
G+ C+ + C +GFQ + +T +D+DECQE GL C CVN
Sbjct: 1528 GNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL----CQGGD-CVNT 1582
Query: 388 VGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGD 444
G + C+C GY + C ++DEC ++ C C NT G+YTC C Y
Sbjct: 1583 FGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYNTLGNYTCVCPAEYLQVNG 1641
Query: 445 GYTCM 449
G CM
Sbjct: 1642 GNNCM 1646
Score = 65.7 bits (153), Expect = 5e-10
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C++ C N Y C C G+ + DG C+DVDEC + C
Sbjct: 2164 CEDIDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ----QDC 2218
Query: 379 HSN-TRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC 435
H+ C N++G + C C G C + +EC C + C NT GS+ C
Sbjct: 2219 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFRC 2277
Query: 436 RCRDGYE 442
C +G++
Sbjct: 2278 DCDEGFQ 2284
Score = 59.7 bits (138), Expect = 3e-08
Identities = 31/71 (43%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCV 468
+D C T+ C + C TP SY C C GY D C+ VDECT S CHH CV
Sbjct: 409 IDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGD-CV 464
Query: 469 NIDGGFRCECF 479
NI G + C C+
Sbjct: 465 NIPGTYHCRCY 475
Score = 56.8 bits (131), Expect = 2e-07
Identities = 65/229 (28%), Positives = 84/229 (36%), Gaps = 39/229 (17%)
Query: 278 ECA-ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA +C +G C D +C C P + G +C +D C C N
Sbjct: 534 ECATSTMCVNG--VCLNEDGSFSCL---CKPGFLLAPGGH---YCMDIDECQTPGIC-VN 584
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDV---DECQ---EAGG----LHGHHCHSNTRC 384
C N + C+C G DG C D C E G G S C
Sbjct: 585 GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 385 VNVVGGY--VCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTPG 431
N G+ CQ C + + + C +++EC + C A+ VC N G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVC-ANGVCENLRG 703
Query: 432 SYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SY C C GYE G C VDEC S C + C N G + C C
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLC-DNGWCQNSPGSYSCSC 751
Score = 55.6 bits (128), Expect = 5e-07
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQ 362
C PQ F+ + + C + C + +A+C N + C C GF D CQ
Sbjct: 2551 CSCPQGFTQHSQWAQ-CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2609
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
DVDEC G G +S C N GG++C C GY R + +CV
Sbjct: 2610 DVDEC---AGRRGPCSYS---CANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 35/213 (16%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-- 357
C R DP C V+ C N C+N + C+C +G D
Sbjct: 846 CERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 905
Query: 358 GLTCQDV-----------DECQ--------------EAGGLHGHHCHSNTRCVNVVGGYV 392
G C DV DEC G + G C + ++ +
Sbjct: 906 GRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDFCCCSIGAVWGVECEACPDPESLEFASL 965
Query: 393 CQCLGGYTRKDKFN----CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-- 446
C G+ +D + +V+EC+ C C NT GS+ C C G+ D
Sbjct: 966 CPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC C CVN G F CECF
Sbjct: 1025 NCTDIDECRISPDLCGQGT-CVNTPGSFECECF 1056
Score = 54.0 bits (124), Expect = 2e-06
Identities = 67/245 (27%), Positives = 88/245 (35%), Gaps = 41/245 (16%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSC- 333
CVC+ G CT VD E A L CD + PG C PG + C
Sbjct: 707 CVCNLGYEAGASGKDCTDVD-ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765
Query: 334 --DE-------NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN- 381
DE + C NL YTCKC G + D G C D + + C N
Sbjct: 766 DVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNL 825
Query: 382 ------TRCVNVVG---GYVCQ-------CLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
+ C +G G C+ C G+ R C +V+ECE C +
Sbjct: 826 QGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGR 884
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC-VNIDGGFRCECFTENCE 484
C NT GS+ C C +G D + VD E C V + G +R + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDFCC--CS 942
Query: 485 LSCSW 489
+ W
Sbjct: 943 IGAVW 947
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/225 (28%), Positives = 82/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGVDYCNM 329
G RF C G QC AC C P + G C GV +
Sbjct: 61 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSC-GV---SR 116
Query: 330 GHSCDENATCMNLNT--KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
G C + +CMN T +C C +G+ G + Q + C + G +G C RC V
Sbjct: 117 GSGC--SVSCMNGGTCRGASCLCQKGYTGT-VCGQPI--C-DRGCHNGGRCIGPNRCACV 170
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHAD-AVCTNTPG---SYTCR------- 436
G QC Y F V + C+ G A+C T G C
Sbjct: 171 YGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 230
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + +T C VDEC C + CVN+ G F C C
Sbjct: 231 PCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRC 274
Score = 49.2 bits (112), Expect = 5e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ C C GY +T C +DEC+ S C
Sbjct: 1563 DIDECQELPGLCQGGD-CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGT 1620
Query: 467 CVNIDGGFRCECFTENCELS 486
C N G + C C E +++
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVN 1640
Score = 48.4 bits (110), Expect = 8e-05
Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 23/226 (10%)
Query: 184 KLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEIT-CRPV-ECDRA 241
KL A + R E + C + +G+ + C+R + T C + ECDR
Sbjct: 1796 KLSPGGACVGRNECREIPNVCSHGDCMDTEGS-YMCLCHRGFQASADQTLCMDIDECDRQ 1854
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECV---CHDGNMQCTRVDPEL 298
C N CL C + +G+ EC V C G+ C
Sbjct: 1855 PCGNGTCKNIIGSYNCL--CFPGFVVTHNGDCVDFDECTTLVGQVCRFGH--CLNTAGSF 1910
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
C C + + G K C + C ++ +C TC NL + C C GFQ
Sbjct: 1911 HCL---CQDGFELTADG---KNCVDTNECLSLAGTCLPG-TCQNLEGSFRCICPPGFQVQ 1963
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C D+DEC E L C T C N G + C C G+ D
Sbjct: 1964 SDHCIDIDECSEEPNL----CLFGT-CTNSPGSFQCLCPPGFVLSD 2004
Score = 44.0 bits (99), Expect = 0.002
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ T C+D+DEC H C
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDEC----STHSSICGPG 1619
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N +G Y C C Y + NC+++
Sbjct: 1620 T-CYNTLGNYTCVCPAEYLQVNGGNNCMDM 1648
Score = 42.3 bits (95), Expect = 0.005
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 350 CNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C +GF + T CQDVDECQ GL C + CVN+VG + C+C G+ D
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGL----CQGGS-CVNMVGSFHCRCPVGHRLSD 282
Score = 33.1 bits (72), Expect = 3.2
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C +VDEC+ C + C N GS+ CRC G+
Sbjct: 245 CQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGH 278
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 142 bits (344), Expect = 3e-33
Identities = 94/302 (31%), Positives = 126/302 (41%), Gaps = 20/302 (6%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C + + G D + +C C G E+T + C D EC
Sbjct: 1058 GYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDEC 1117
Query: 244 K-NPVLHP-GECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELAC 300
+ L P G+C QC +R + EC +G ++ E
Sbjct: 1118 SLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GS 1176
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DG 358
R C G C VD C + C N+ + C C GF D
Sbjct: 1177 YRCSCGQGYSLMPDGRACA---DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDM 1233
Query: 359 LTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGN 416
TC DVDEC L+ H C H + C N G +VC C GY RK C +VDECE
Sbjct: 1234 RTCVDVDECD----LNPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 417 THGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
H C + A C N PGS++CRC G+ GDG+ C +DEC H C C+N+ G +RC
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC 1347
Query: 477 EC 478
C
Sbjct: 1348 TC 1349
Score = 140 bits (339), Expect = 1e-32
Identities = 65/160 (40%), Positives = 85/160 (53%), Gaps = 8/160 (5%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHC 378
C VD C++ + C N + C C G+ G T C DVDEC E GG H+C
Sbjct: 1236 CVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC-EVGG---HNC 1291
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ C+N+ G + C+CL G+ D F C ++DEC H C C N PGSY C CR
Sbjct: 1292 DSHASCLNIPGSFSCRCLPGWVG-DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+ C DEC E C + +C+N GG+RCEC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCEC 1389
Score = 124 bits (300), Expect = 8e-28
Identities = 63/166 (37%), Positives = 80/166 (48%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C VD C TC N + Y C+C G + G C+D+DEC + GL H
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH 1126
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+CVNV+G + C C G+ + D+ CV+++EC GC D C NT GSY C
Sbjct: 1127 G-----QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRC 1179
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C GY DG C VDEC E C C N+ GG RC C+
Sbjct: 1180 SCGQGYSLMPDGRACADVDECEENPRVCDQG-HCTNMPGGHRCLCY 1224
Score = 115 bits (277), Expect = 5e-25
Identities = 68/178 (38%), Positives = 91/178 (51%), Gaps = 16/178 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C + H C C+N+ Y C C QGF GDG C+D DEC E L C
Sbjct: 1319 CHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL----C- 1373
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
N +C+N GGY C+C G+ +D C +VDEC +GN C A C N PG + C C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL--C-AFGSCENLPGMFRCIC 1430
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRV 493
GYE D G C ++EC + + C + C+N G + C C ++ EL+ S G V
Sbjct: 1431 NGGYELDRGGGNCTDINECADPVN-CINGV-CINTPGSYLCSC-PQDFELNPSGVGCV 1485
Score = 114 bits (275), Expect = 8e-25
Identities = 75/209 (35%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 278 ECAEC--VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE VC +G C D C C P +S+ C D C++GH C +
Sbjct: 2087 ECAENPGVCTNG--VCVNTDGSFRCE---C--PFGYSLDFTGIN-CVDTDECSVGHPCGQ 2138
Query: 336 NATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
TC N+ + C C GF+ G +TC+D+DEC L CH N G Y+C
Sbjct: 2139 G-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCH------NTEGSYLCT 2191
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAV-CTNTPGSYTCRCRDGYE---GDGYTCM 449
C GYT R+D C +VDEC CHA + C N G++ C C G G G C
Sbjct: 2192 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC C + RCVN G FRC+C
Sbjct: 2252 DDNECHAQPDLCVNG-RCVNTAGSFRCDC 2279
Score = 111 bits (267), Expect = 7e-24
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 14/144 (9%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C C +G+ + DG TC+D+DEC H+C CVN VG + C+C
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS----RQHNCQF--LCVNTVGAFTCRCP 2473
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDEC 454
G+T+ + C + DEC C A C NTPGS+ C C G+ G+ C V+EC
Sbjct: 2474 PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
+G H C H C N GG+RC C
Sbjct: 2533 -DGPHRCQHG--CQNQLGGYRCSC 2553
Score = 111 bits (266), Expect = 1e-23
Identities = 59/160 (36%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC GH C
Sbjct: 2085 VNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-----GHPCGQG 2139
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+GG+ C C G+ C ++DEC N C C NT GSY C C GY
Sbjct: 2140 T-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGY 2196
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
DG C VDEC +G CH C N+ G F C C
Sbjct: 2197 TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Score = 109 bits (262), Expect = 3e-23
Identities = 94/311 (30%), Positives = 125/311 (40%), Gaps = 39/311 (12%)
Query: 193 SRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD------RAECKNP 246
S E+C+ +C + G G T D N C G C C R EC
Sbjct: 844 SPCERCEIDPAC-ARGFARMTGVTCD-DVNECESFPG--VCPNGRCVNTAGSFRCECPEG 899
Query: 247 VLHPGE---CCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDG---NMQCTRV-DPEL 298
++ C L C L + E G K + C C G ++C DPE
Sbjct: 900 LMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYLMDVCCCSIGAVWGVECEACPDPES 959
Query: 299 A-----CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
CPR + F + G F V+ C + + TC N + C C G
Sbjct: 960 LEFASLCPRGLGFASRDF-LSGR--PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGG 1016
Query: 354 FQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF--NCVE 409
F D C D+DEC+ + L C T CVN G + C+C GY NC++
Sbjct: 1017 FALDAQERNCTDIDECRISPDL----CGQGT-CVNTPGSFECECFPGYESGFMLMKNCMD 1071
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARC 467
VDEC + C CTNT GSY C+C G+E G C +DEC+ C H +C
Sbjct: 1072 VDECARDPLLCRG-GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQC 1129
Query: 468 VNIDGGFRCEC 478
VN+ G F+C C
Sbjct: 1130 VNVIGAFQCSC 1140
Score = 107 bits (256), Expect = 2e-22
Identities = 69/183 (37%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-- 359
R C+ V GEC VD C C + C+N+ Y C+C GFQ
Sbjct: 432 RCECNVGYTQDVRGECID----VDECTSS-PC-HHGDCVNIPGTYHCRCYPGFQATPTRQ 485
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTH 418
C DVDEC +GGL CH RCVN G + C C G+ D NCV+ +EC +T
Sbjct: 486 ACVDVDECIVSGGL----CHLG-RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 419 GCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
C + VC N GS++C C+ G+ G+ CM +DEC T G H C N +G FR
Sbjct: 541 -C-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH---CTNTEGSFR 595
Query: 476 CEC 478
C+C
Sbjct: 596 CQC 598
Score = 103 bits (247), Expect = 2e-21
Identities = 67/205 (32%), Positives = 85/205 (41%), Gaps = 19/205 (9%)
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG--VDYCNM-GHSCDEN 336
AEC C G R + CP LP + P G VD C M H C +
Sbjct: 2322 AECCCGGGRGWGPRCE---LCP-LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AH 2376
Query: 337 ATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N + C C G+ D TC D+DEC + C C N G ++C
Sbjct: 2377 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP----KPC--TFLCKNTKGSFLCS 2430
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C GY +D C ++DEC H C +C NT G++TCRC G+ C DE
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDNDE 2488
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
C+ C C N G FRCEC
Sbjct: 2489 CSAQPGPCGAHGHCHNTPGSFRCEC 2513
Score = 99 bits (238), Expect = 2e-20
Identities = 56/161 (34%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSN 381
+D C + N C+N + C+C GF + L C+DVDEC G C N
Sbjct: 1722 IDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC----GSRESPCQQN 1777
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDG 440
C+N+ G Y C+C GY CV +EC + C H D C +T GSY C C G
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGD--CMDTEGSYMCLCHRG 1835
Query: 441 YE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
++ D CM +DEC C + C NI G + C CF
Sbjct: 1836 FQASADQTLCMDIDECDR--QPCGNGT-CKNIIGSYNCLCF 1873
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/159 (35%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNT 382
+D C + N C+ + Y C+CN G+ D C DVDEC + HG
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD------ 462
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN+ G Y C+C G+ + CV+VDEC + CH C NT GS+ C C G+
Sbjct: 463 -CVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAGF 520
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E DG C+ +EC S C + C+N DG F C C
Sbjct: 521 ELSPDGKNCVDHNECAT-STMCVNGV-CLNEDGSFSCLC 557
Score = 95.5 bits (227), Expect = 5e-19
Identities = 70/220 (31%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 265 GNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV 324
G L E R K+ EC N Q V+ A C P F+ + C
Sbjct: 2434 GYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGA---FTCRCPPGFTQHHQACF---DN 2486
Query: 325 DYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
D C+ C + C N + C+C+QGF G C+DV+EC H C
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGP-----HRCQHG 2541
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N +GGY C C G+T+ ++ CV+ +EC + C A C NT G + C C G
Sbjct: 2542 --CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC-GSASCRNTLGGFRCVCPSG 2598
Query: 441 YEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++ D C VDEC C +S C N GGF C C
Sbjct: 2599 FDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGC 2636
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/178 (31%), Positives = 81/178 (45%), Gaps = 13/178 (7%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQ 362
C+ P F+ C VD C S C +NA C+N+ Y CKC +G++ G C
Sbjct: 1746 CECPAGFNY-NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACV 1804
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
+EC+E + C S+ C++ G Y+C C G+ D+ C+++DEC+ G
Sbjct: 1805 GRNECREIPNV----C-SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG-- 1857
Query: 422 ADAVCTNTPGSYTCRCRDGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C N GSY C C G+ C+ DECT C+N G F C C
Sbjct: 1858 -NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLC 1914
Score = 91.1 bits (216), Expect = 1e-17
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGDGLTCQDVDECQEAGGLHGH 376
C +D C+ C N TC N+ Y C C GF GD C D DEC L G
Sbjct: 1845 CMDIDECDR-QPCG-NGTCKNIIGSYNCLCFPGFVVTHNGD---CVDFDECTT---LVGQ 1896
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N G + C C G+ D NCV+ +EC C C N GS+ C
Sbjct: 1897 VCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPGTCQNLEGSFRC 1954
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ C+ +DEC+E + C C N G F+C C
Sbjct: 1955 ICPPGFQVQSDHCIDIDECSEEPNLCLFGT-CTNSPGSFQCLC 1996
Score = 90.2 bits (214), Expect = 2e-17
Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHH 377
C +D C + TC+N + C+C G++ + C DVDEC L
Sbjct: 1026 CTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLL---- 1081
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C T C N G Y CQC G+ K C ++DEC + G C N G++ C
Sbjct: 1082 CRGGT-CTNTDGSYKCQCPPGHELTAKGTACEDIDEC-SLSDGLCPHGQCVNVIGAFQCS 1139
Query: 437 CRDGYEG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C+ ++EC + C C+N +G +RC C
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRCSC 1181
Score = 85.0 bits (201), Expect = 7e-16
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCH 421
D+DEC E + C +N C+N +G + C+C G+ C +VDEC C
Sbjct: 1721 DIDECGEIPAI----C-ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 422 ADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+A C N PGSY C+C GY+ G C+ +EC E + C H C++ +G + C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH-GDCMDTEGSYMCLC 1832
Score = 83.0 bits (196), Expect = 3e-15
Identities = 59/179 (32%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLP----CDPPQQFSVPGECCKFCPGVDY 326
G+ F + ECV + R P C +P C Q F+ G FC D
Sbjct: 1314 GDGFECHDLDECVSQEH-----RCSPRGDCLNVPGSYRCTCRQGFAGDGF---FCEDRDE 1365
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +N C+N Y C+C GF D CQDVDEC + G+ C + C
Sbjct: 1366 CAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-----GNLCAFGS-C 1419
Query: 385 VNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
N+ G + C C GGY + NC +++EC + C + VC NTPGSY C C +E
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVN-C-INGVCINTPGSYLCSCPQDFE 1476
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/165 (35%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ G C DVDEC L+ C N
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC----ALNSLLC-DN 737
Query: 382 TRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C G+ +D C +VDEC + C VC N GSYTC+C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--C-VSGVCRNLAGSYTCKCGPG 794
Query: 441 YEGD--GYTCMHVDECTEGSHTCH---HSARC-VNIDG-GFRCEC 478
D G C+ + T+G TC +RC VN+ G R EC
Sbjct: 795 SRLDPSGTFCL---DSTKG--TCWLKIQESRCEVNLQGASLRSEC 834
Score = 77.8 bits (183), Expect = 1e-13
Identities = 65/234 (27%), Positives = 94/234 (40%), Gaps = 37/234 (15%)
Query: 240 RAEC-KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R +C + L PG C +C N+ HG+ + C+CH G C
Sbjct: 1788 RCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCM 1846
Query: 293 RVDPELACPRLPCDPPQQFSVPGE--CCKF----------CPGVDYCN--MGHSCDENAT 338
+D C R PC ++ G C F C D C +G C
Sbjct: 1847 DIDE---CDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGH 1902
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C+N + C C GF+ DG C D +EC G C T C N+ G + C C
Sbjct: 1903 CLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT----CLPGT-CQNLEGSFRCICP 1957
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTC 448
G+ + +C+++DEC + C CTN+PGS+ C C G+ +G+ C
Sbjct: 1958 PGFQVQSD-HCIDIDECSEEPNLC-LFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 75.8 bits (178), Expect = 5e-13
Identities = 60/207 (28%), Positives = 84/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT +C + GE EC CH G+ C + C C P
Sbjct: 422 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD--CVNIPGTYHCR---CYP 476
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q + + C VD C + C+N + C CN GF+ DG C D +
Sbjct: 477 GFQATPTRQACV---DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHN 533
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ + C+++DEC+ T G +
Sbjct: 534 ECATST-----MC-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ--TPGICVNG 585
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCM 449
CTNT GS+ C+C G DG C+
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCV 612
Score = 73.3 bits (172), Expect = 2e-12
Identities = 44/122 (36%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C+ H C C N Y C C QGF Q VDE + A L C S
Sbjct: 2526 CEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGS 2581
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N +GG+ C C G+ C +VDEC G C C NTPG + C C
Sbjct: 2582 AS-CRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGCPQ 2638
Query: 440 GY 441
GY
Sbjct: 2639 GY 2640
Score = 72.5 bits (170), Expect = 4e-12
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 35/190 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGG 372
G K C VD C + +N C N Y+C C GF D C+DVDEC +
Sbjct: 716 GASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSS-- 773
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD----------KFNC---VEVDECEGNTHG 419
C S C N+ G Y C+C G +R D K C ++ CE N G
Sbjct: 774 ----PCVSGV-CRNLAGSYTCKC-GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQG 827
Query: 420 CHADAVCTNTPGS---YTCR-------CRDGY-EGDGYTCMHVDECTEGSHTCHHSARCV 468
+ C T G+ C C G+ G TC V+EC C + RCV
Sbjct: 828 ASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCV 886
Query: 469 NIDGGFRCEC 478
N G FRCEC
Sbjct: 887 NTAGSFRCEC 896
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 11/125 (8%)
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNV 387
G+ C+ + C +GFQ + +T +D+DECQE GL C CVN
Sbjct: 1528 GNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL----CQGGD-CVNT 1582
Query: 388 VGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGD 444
G + C+C GY + C ++DEC ++ C C NT G+YTC C Y
Sbjct: 1583 FGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYNTLGNYTCVCPAEYLQVNG 1641
Query: 445 GYTCM 449
G CM
Sbjct: 1642 GNNCM 1646
Score = 65.7 bits (153), Expect = 5e-10
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C++ C N Y C C G+ + DG C+DVDEC + C
Sbjct: 2164 CEDIDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ----QDC 2218
Query: 379 HSN-TRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC 435
H+ C N++G + C C G C + +EC C + C NT GS+ C
Sbjct: 2219 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFRC 2277
Query: 436 RCRDGYE 442
C +G++
Sbjct: 2278 DCDEGFQ 2284
Score = 59.7 bits (138), Expect = 3e-08
Identities = 31/71 (43%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCV 468
+D C T+ C + C TP SY C C GY D C+ VDECT S CHH CV
Sbjct: 409 IDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGD-CV 464
Query: 469 NIDGGFRCECF 479
NI G + C C+
Sbjct: 465 NIPGTYHCRCY 475
Score = 56.8 bits (131), Expect = 2e-07
Identities = 65/229 (28%), Positives = 84/229 (36%), Gaps = 39/229 (17%)
Query: 278 ECA-ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA +C +G C D +C C P + G +C +D C C N
Sbjct: 534 ECATSTMCVNG--VCLNEDGSFSCL---CKPGFLLAPGGH---YCMDIDECQTPGIC-VN 584
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDV---DECQ---EAGG----LHGHHCHSNTRC 384
C N + C+C G DG C D C E G G S C
Sbjct: 585 GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 385 VNVVGGY--VCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTPG 431
N G+ CQ C + + + C +++EC + C A+ VC N G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVC-ANGVCENLRG 703
Query: 432 SYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SY C C GYE G C VDEC S C + C N G + C C
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLC-DNGWCQNSPGSYSCSC 751
Score = 55.6 bits (128), Expect = 5e-07
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQ 362
C PQ F+ + + C + C + +A+C N + C C GF D CQ
Sbjct: 2551 CSCPQGFTQHSQWAQ-CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2609
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
DVDEC G G +S C N GG++C C GY R + +CV
Sbjct: 2610 DVDEC---AGRRGPCSYS---CANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 35/213 (16%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-- 357
C R DP C V+ C N C+N + C+C +G D
Sbjct: 846 CERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 905
Query: 358 GLTCQDV-----------DECQ--------------EAGGLHGHHCHSNTRCVNVVGGYV 392
G C DV DEC G + G C + ++ +
Sbjct: 906 GRLCVDVRLEPCFLRWDEDECGVTLPGKYLMDVCCCSIGAVWGVECEACPDPESLEFASL 965
Query: 393 CQCLGGYTRKDKFN----CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-- 446
C G+ +D + +V+EC+ C C NT GS+ C C G+ D
Sbjct: 966 CPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC C CVN G F CECF
Sbjct: 1025 NCTDIDECRISPDLCGQGT-CVNTPGSFECECF 1056
Score = 53.6 bits (123), Expect = 2e-06
Identities = 60/208 (28%), Positives = 78/208 (37%), Gaps = 40/208 (19%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSC- 333
CVC+ G CT VD E A L CD + PG C PG + C
Sbjct: 707 CVCNLGYEAGASGKDCTDVD-ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765
Query: 334 --DE-------NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN- 381
DE + C NL YTCKC G + D G C D + + C N
Sbjct: 766 DVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNL 825
Query: 382 ------TRCVNVVG---GYVCQ-------CLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
+ C +G G C+ C G+ R C +V+ECE C +
Sbjct: 826 QGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGR 884
Query: 426 CTNTPGSYTCRCRDG--YEGDGYTCMHV 451
C NT GS+ C C +G + G C+ V
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDV 912
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/225 (28%), Positives = 82/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGVDYCNM 329
G RF C G QC AC C P + G C GV +
Sbjct: 61 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSC-GV---SR 116
Query: 330 GHSCDENATCMNLNT--KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
G C + +CMN T +C C +G+ G + Q + C + G +G C RC V
Sbjct: 117 GSGC--SVSCMNGGTCRGASCLCQKGYTGT-VCGQPI--C-DRGCHNGGRCIGPNRCACV 170
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHAD-AVCTNTPG---SYTCR------- 436
G QC Y F V + C+ G A+C T G C
Sbjct: 171 YGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 230
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + +T C VDEC C + CVN+ G F C C
Sbjct: 231 PCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRC 274
Score = 49.2 bits (112), Expect = 5e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ C C GY +T C +DEC+ S C
Sbjct: 1563 DIDECQELPGLCQGGD-CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGT 1620
Query: 467 CVNIDGGFRCECFTENCELS 486
C N G + C C E +++
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVN 1640
Score = 48.4 bits (110), Expect = 8e-05
Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 23/226 (10%)
Query: 184 KLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEIT-CRPV-ECDRA 241
KL A + R E + C + +G+ + C+R + T C + ECDR
Sbjct: 1796 KLSPGGACVGRNECREIPNVCSHGDCMDTEGS-YMCLCHRGFQASADQTLCMDIDECDRQ 1854
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECV---CHDGNMQCTRVDPEL 298
C N CL C + +G+ EC V C G+ C
Sbjct: 1855 PCGNGTCKNIIGSYNCL--CFPGFVVTHNGDCVDFDECTTLVGQVCRFGH--CLNTAGSF 1910
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
C C + + G K C + C ++ +C TC NL + C C GFQ
Sbjct: 1911 HCL---CQDGFELTADG---KNCVDTNECLSLAGTCLPG-TCQNLEGSFRCICPPGFQVQ 1963
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C D+DEC E L C T C N G + C C G+ D
Sbjct: 1964 SDHCIDIDECSEEPNL----CLFGT-CTNSPGSFQCLCPPGFVLSD 2004
Score = 44.0 bits (99), Expect = 0.002
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ T C+D+DEC H C
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDEC----STHSSICGPG 1619
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N +G Y C C Y + NC+++
Sbjct: 1620 T-CYNTLGNYTCVCPAEYLQVNGGNNCMDM 1648
Score = 42.3 bits (95), Expect = 0.005
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 350 CNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C +GF + T CQDVDECQ GL C + CVN+VG + C+C G+ D
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGL----CQGGS-CVNMVGSFHCRCPVGHRLSD 282
Score = 33.1 bits (72), Expect = 3.2
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C +VDEC+ C + C N GS+ CRC G+
Sbjct: 245 CQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGH 278
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 142 bits (344), Expect = 3e-33
Identities = 94/302 (31%), Positives = 126/302 (41%), Gaps = 20/302 (6%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C + + G D + +C C G E+T + C D EC
Sbjct: 1058 GYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDEC 1117
Query: 244 K-NPVLHP-GECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELAC 300
+ L P G+C QC +R + EC +G ++ E
Sbjct: 1118 SLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GS 1176
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DG 358
R C G C VD C + C N+ + C C GF D
Sbjct: 1177 YRCSCGQGYSLMPDGRACA---DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDM 1233
Query: 359 LTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGN 416
TC DVDEC L+ H C H + C N G +VC C GY RK C +VDECE
Sbjct: 1234 RTCVDVDECD----LNPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 417 THGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
H C + A C N PGS++CRC G+ GDG+ C +DEC H C C+N+ G +RC
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC 1347
Query: 477 EC 478
C
Sbjct: 1348 TC 1349
Score = 140 bits (339), Expect = 1e-32
Identities = 65/160 (40%), Positives = 85/160 (53%), Gaps = 8/160 (5%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHC 378
C VD C++ + C N + C C G+ G T C DVDEC E GG H+C
Sbjct: 1236 CVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC-EVGG---HNC 1291
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ C+N+ G + C+CL G+ D F C ++DEC H C C N PGSY C CR
Sbjct: 1292 DSHASCLNIPGSFSCRCLPGWVG-DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+ C DEC E C + +C+N GG+RCEC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCEC 1389
Score = 124 bits (300), Expect = 8e-28
Identities = 63/166 (37%), Positives = 80/166 (48%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C VD C TC N + Y C+C G + G C+D+DEC + GL H
Sbjct: 1067 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH 1126
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+CVNV+G + C C G+ + D+ CV+++EC GC D C NT GSY C
Sbjct: 1127 G-----QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRC 1179
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C GY DG C VDEC E C C N+ GG RC C+
Sbjct: 1180 SCGQGYSLMPDGRACADVDECEENPRVCDQG-HCTNMPGGHRCLCY 1224
Score = 115 bits (277), Expect = 5e-25
Identities = 68/178 (38%), Positives = 91/178 (51%), Gaps = 16/178 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C + H C C+N+ Y C C QGF GDG C+D DEC E L C
Sbjct: 1319 CHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL----C- 1373
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
N +C+N GGY C+C G+ +D C +VDEC +GN C A C N PG + C C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL--C-AFGSCENLPGMFRCIC 1430
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRV 493
GYE D G C ++EC + + C + C+N G + C C ++ EL+ S G V
Sbjct: 1431 NGGYELDRGGGNCTDINECADPVN-CINGV-CINTPGSYLCSC-PQDFELNPSGVGCV 1485
Score = 114 bits (275), Expect = 8e-25
Identities = 75/209 (35%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 278 ECAEC--VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE VC +G C D C C P +S+ C D C++GH C +
Sbjct: 2087 ECAENPGVCTNG--VCVNTDGSFRCE---C--PFGYSLDFTGIN-CVDTDECSVGHPCGQ 2138
Query: 336 NATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
TC N+ + C C GF+ G +TC+D+DEC L CH N G Y+C
Sbjct: 2139 G-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCH------NTEGSYLCT 2191
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAV-CTNTPGSYTCRCRDGYE---GDGYTCM 449
C GYT R+D C +VDEC CHA + C N G++ C C G G G C
Sbjct: 2192 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC C + RCVN G FRC+C
Sbjct: 2252 DDNECHAQPDLCVNG-RCVNTAGSFRCDC 2279
Score = 111 bits (267), Expect = 7e-24
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 14/144 (9%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C C +G+ + DG TC+D+DEC H+C CVN VG + C+C
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS----RQHNCQF--LCVNTVGAFTCRCP 2473
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDEC 454
G+T+ + C + DEC C A C NTPGS+ C C G+ G+ C V+EC
Sbjct: 2474 PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
+G H C H C N GG+RC C
Sbjct: 2533 -DGPHRCQHG--CQNQLGGYRCSC 2553
Score = 111 bits (266), Expect = 1e-23
Identities = 59/160 (36%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC GH C
Sbjct: 2085 VNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-----GHPCGQG 2139
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+GG+ C C G+ C ++DEC N C C NT GSY C C GY
Sbjct: 2140 T-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGY 2196
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
DG C VDEC +G CH C N+ G F C C
Sbjct: 2197 TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Score = 108 bits (260), Expect = 5e-23
Identities = 94/311 (30%), Positives = 125/311 (40%), Gaps = 39/311 (12%)
Query: 193 SRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD------RAECKNP 246
S E+C+ +C + G G T D N C G C C R EC
Sbjct: 844 SPCERCEIDPAC-ARGFARMTGVTCD-DVNECESFPG--VCPNGRCVNTAGSFRCECPEG 899
Query: 247 VLHPGE---CCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDG---NMQCTRV-DPEL 298
++ C L C L + E G K + C C G ++C DPE
Sbjct: 900 LMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPES 959
Query: 299 A-----CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
CPR + F + G F V+ C + + TC N + C C G
Sbjct: 960 LEFASLCPRGLGFASRDF-LSGR--PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGG 1016
Query: 354 FQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF--NCVE 409
F D C D+DEC+ + L C T CVN G + C+C GY NC++
Sbjct: 1017 FALDAQERNCTDIDECRISPDL----CGQGT-CVNTPGSFECECFPGYESGFMLMKNCMD 1071
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARC 467
VDEC + C CTNT GSY C+C G+E G C +DEC+ C H +C
Sbjct: 1072 VDECARDPLLCRG-GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQC 1129
Query: 468 VNIDGGFRCEC 478
VN+ G F+C C
Sbjct: 1130 VNVIGAFQCSC 1140
Score = 106 bits (255), Expect = 2e-22
Identities = 69/183 (37%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-- 359
R C+ V GEC VD C C + C+N+ Y C+C GFQ
Sbjct: 432 RCECNVGYTQDVRGECID----VDECTSS-PC-HHGDCVNIPGTYHCQCYPGFQATPTRQ 485
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTH 418
C DVDEC +GGL CH RCVN G + C C G+ D NCV+ +EC +T
Sbjct: 486 ACVDVDECIVSGGL----CHLG-RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 419 GCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
C + VC N GS++C C+ G+ G+ CM +DEC T G H C N +G FR
Sbjct: 541 -C-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH---CTNTEGSFR 595
Query: 476 CEC 478
C+C
Sbjct: 596 CQC 598
Score = 103 bits (247), Expect = 2e-21
Identities = 67/205 (32%), Positives = 85/205 (41%), Gaps = 19/205 (9%)
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG--VDYCNM-GHSCDEN 336
AEC C G R + CP LP + P G VD C M H C +
Sbjct: 2322 AECCCGGGRGWGPRCE---LCP-LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AH 2376
Query: 337 ATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N + C C G+ D TC D+DEC + C C N G ++C
Sbjct: 2377 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP----KPC--TFLCKNTKGSFLCS 2430
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C GY +D C ++DEC H C +C NT G++TCRC G+ C DE
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDNDE 2488
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
C+ C C N G FRCEC
Sbjct: 2489 CSAQPGPCGAHGHCHNTPGSFRCEC 2513
Score = 99 bits (238), Expect = 2e-20
Identities = 56/161 (34%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSN 381
+D C + N C+N + C+C GF + L C+DVDEC G C N
Sbjct: 1722 IDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC----GSRESPCQQN 1777
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDG 440
C+N+ G Y C+C GY CV +EC + C H D C +T GSY C C G
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGD--CMDTEGSYMCLCHRG 1835
Query: 441 YE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
++ D CM +DEC C + C NI G + C CF
Sbjct: 1836 FQASADQTLCMDIDECDR--QPCGNGT-CKNIIGSYNCLCF 1873
Score = 97.1 bits (231), Expect = 2e-19
Identities = 58/159 (36%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNT 382
+D C + N C+ + Y C+CN G+ D C DVDEC + HG
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD------ 462
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN+ G Y CQC G+ + CV+VDEC + CH C NT GS+ C C G+
Sbjct: 463 -CVNIPGTYHCQCYPGFQATPTRQACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAGF 520
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E DG C+ +EC S C + C+N DG F C C
Sbjct: 521 ELSPDGKNCVDHNECAT-STMCVNGV-CLNEDGSFSCLC 557
Score = 95.5 bits (227), Expect = 5e-19
Identities = 70/220 (31%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 265 GNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV 324
G L E R K+ EC N Q V+ A C P F+ + C
Sbjct: 2434 GYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGA---FTCRCPPGFTQHHQACF---DN 2486
Query: 325 DYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
D C+ C + C N + C+C+QGF G C+DV+EC H C
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGP-----HRCQHG 2541
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N +GGY C C G+T+ ++ CV+ +EC + C A C NT G + C C G
Sbjct: 2542 --CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC-GSASCRNTLGGFRCVCPSG 2598
Query: 441 YEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++ D C VDEC C +S C N GGF C C
Sbjct: 2599 FDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGC 2636
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/178 (31%), Positives = 81/178 (45%), Gaps = 13/178 (7%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQ 362
C+ P F+ C VD C S C +NA C+N+ Y CKC +G++ G C
Sbjct: 1746 CECPAGFNY-NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACV 1804
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
+EC+E + C S+ C++ G Y+C C G+ D+ C+++DEC+ G
Sbjct: 1805 GRNECREIPNV----C-SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG-- 1857
Query: 422 ADAVCTNTPGSYTCRCRDGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C N GSY C C G+ C+ DECT C+N G F C C
Sbjct: 1858 -NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLC 1914
Score = 91.1 bits (216), Expect = 1e-17
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGDGLTCQDVDECQEAGGLHGH 376
C +D C+ C N TC N+ Y C C GF GD C D DEC L G
Sbjct: 1845 CMDIDECDR-QPCG-NGTCKNIIGSYNCLCFPGFVVTHNGD---CVDFDECTT---LVGQ 1896
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N G + C C G+ D NCV+ +EC C C N GS+ C
Sbjct: 1897 VCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPGTCQNLEGSFRC 1954
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ C+ +DEC+E + C C N G F+C C
Sbjct: 1955 ICPPGFQVQSDHCIDIDECSEEPNLCLFGT-CTNSPGSFQCLC 1996
Score = 90.2 bits (214), Expect = 2e-17
Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHH 377
C +D C + TC+N + C+C G++ + C DVDEC L
Sbjct: 1026 CTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLL---- 1081
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C T C N G Y CQC G+ K C ++DEC + G C N G++ C
Sbjct: 1082 CRGGT-CTNTDGSYKCQCPPGHELTAKGTACEDIDEC-SLSDGLCPHGQCVNVIGAFQCS 1139
Query: 437 CRDGYEG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C+ ++EC + C C+N +G +RC C
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRCSC 1181
Score = 85.0 bits (201), Expect = 7e-16
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCH 421
D+DEC E + C +N C+N +G + C+C G+ C +VDEC C
Sbjct: 1721 DIDECGEIPAI----C-ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 422 ADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+A C N PGSY C+C GY+ G C+ +EC E + C H C++ +G + C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH-GDCMDTEGSYMCLC 1832
Score = 83.0 bits (196), Expect = 3e-15
Identities = 59/179 (32%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLP----CDPPQQFSVPGECCKFCPGVDY 326
G+ F + ECV + R P C +P C Q F+ G FC D
Sbjct: 1314 GDGFECHDLDECVSQEH-----RCSPRGDCLNVPGSYRCTCRQGFAGDGF---FCEDRDE 1365
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +N C+N Y C+C GF D CQDVDEC + G+ C + C
Sbjct: 1366 CAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-----GNLCAFGS-C 1419
Query: 385 VNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
N+ G + C C GGY + NC +++EC + C + VC NTPGSY C C +E
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVN-C-INGVCINTPGSYLCSCPQDFE 1476
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/165 (35%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ G C DVDEC L+ C N
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC----ALNSLLC-DN 737
Query: 382 TRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C G+ +D C +VDEC + C VC N GSYTC+C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--C-VSGVCRNLAGSYTCKCGPG 794
Query: 441 YEGD--GYTCMHVDECTEGSHTCH---HSARC-VNIDG-GFRCEC 478
D G C+ + T+G TC +RC VN+ G R EC
Sbjct: 795 SRLDPSGTFCL---DSTKG--TCWLKIQESRCEVNLQGASLRSEC 834
Score = 77.8 bits (183), Expect = 1e-13
Identities = 65/234 (27%), Positives = 94/234 (40%), Gaps = 37/234 (15%)
Query: 240 RAEC-KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R +C + L PG C +C N+ HG+ + C+CH G C
Sbjct: 1788 RCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCM 1846
Query: 293 RVDPELACPRLPCDPPQQFSVPGE--CCKF----------CPGVDYCN--MGHSCDENAT 338
+D C R PC ++ G C F C D C +G C
Sbjct: 1847 DIDE---CDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGH 1902
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C+N + C C GF+ DG C D +EC G C T C N+ G + C C
Sbjct: 1903 CLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT----CLPGT-CQNLEGSFRCICP 1957
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTC 448
G+ + +C+++DEC + C CTN+PGS+ C C G+ +G+ C
Sbjct: 1958 PGFQVQSD-HCIDIDECSEEPNLC-LFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 76.2 bits (179), Expect = 3e-13
Identities = 60/207 (28%), Positives = 84/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT +C + GE EC CH G+ C + C C P
Sbjct: 422 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD--CVNIPGTYHCQ---CYP 476
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q + + C VD C + C+N + C CN GF+ DG C D +
Sbjct: 477 GFQATPTRQACV---DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHN 533
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ + C+++DEC+ T G +
Sbjct: 534 ECATST-----MC-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ--TPGICVNG 585
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCM 449
CTNT GS+ C+C G DG C+
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCV 612
Score = 73.3 bits (172), Expect = 2e-12
Identities = 44/122 (36%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C+ H C C N Y C C QGF Q VDE + A L C S
Sbjct: 2526 CEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGS 2581
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N +GG+ C C G+ C +VDEC G C C NTPG + C C
Sbjct: 2582 AS-CRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGCPQ 2638
Query: 440 GY 441
GY
Sbjct: 2639 GY 2640
Score = 72.5 bits (170), Expect = 4e-12
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 35/190 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGG 372
G K C VD C + +N C N Y+C C GF D C+DVDEC +
Sbjct: 716 GASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSS-- 773
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD----------KFNC---VEVDECEGNTHG 419
C S C N+ G Y C+C G +R D K C ++ CE N G
Sbjct: 774 ----PCVSGV-CRNLAGSYTCKC-GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQG 827
Query: 420 CHADAVCTNTPGS---YTCR-------CRDGY-EGDGYTCMHVDECTEGSHTCHHSARCV 468
+ C T G+ C C G+ G TC V+EC C + RCV
Sbjct: 828 ASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCV 886
Query: 469 NIDGGFRCEC 478
N G FRCEC
Sbjct: 887 NTAGSFRCEC 896
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 11/125 (8%)
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNV 387
G+ C+ + C +GFQ + +T +D+DECQE GL C CVN
Sbjct: 1528 GNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL----CQGGD-CVNT 1582
Query: 388 VGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGD 444
G + C+C GY + C ++DEC ++ C C NT G+YTC C Y
Sbjct: 1583 FGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYNTLGNYTCVCPAEYLQVNG 1641
Query: 445 GYTCM 449
G CM
Sbjct: 1642 GNNCM 1646
Score = 65.7 bits (153), Expect = 5e-10
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C++ C N Y C C G+ + DG C+DVDEC + C
Sbjct: 2164 CEDIDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ----QDC 2218
Query: 379 HSN-TRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC 435
H+ C N++G + C C G C + +EC C + C NT GS+ C
Sbjct: 2219 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFRC 2277
Query: 436 RCRDGYE 442
C +G++
Sbjct: 2278 DCDEGFQ 2284
Score = 60.5 bits (140), Expect = 2e-08
Identities = 31/71 (43%), Positives = 38/71 (53%), Gaps = 5/71 (7%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCV 468
+D C T+ C + C TP SY C C GY D C+ VDECT S CHH CV
Sbjct: 409 IDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGD-CV 464
Query: 469 NIDGGFRCECF 479
NI G + C+C+
Sbjct: 465 NIPGTYHCQCY 475
Score = 56.8 bits (131), Expect = 2e-07
Identities = 65/229 (28%), Positives = 84/229 (36%), Gaps = 39/229 (17%)
Query: 278 ECA-ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA +C +G C D +C C P + G +C +D C C N
Sbjct: 534 ECATSTMCVNG--VCLNEDGSFSCL---CKPGFLLAPGGH---YCMDIDECQTPGIC-VN 584
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDV---DECQ---EAGG----LHGHHCHSNTRC 384
C N + C+C G DG C D C E G G S C
Sbjct: 585 GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 385 VNVVGGY--VCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTPG 431
N G+ CQ C + + + C +++EC + C A+ VC N G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVC-ANGVCENLRG 703
Query: 432 SYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SY C C GYE G C VDEC S C + C N G + C C
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLC-DNGWCQNSPGSYSCSC 751
Score = 55.6 bits (128), Expect = 5e-07
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQ 362
C PQ F+ + + C + C + +A+C N + C C GF D CQ
Sbjct: 2551 CSCPQGFTQHSQWAQ-CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2609
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
DVDEC G G +S C N GG++C C GY R + +CV
Sbjct: 2610 DVDEC---AGRRGPCSYS---CANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 54.4 bits (125), Expect = 1e-06
Identities = 67/245 (27%), Positives = 88/245 (35%), Gaps = 41/245 (16%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSC- 333
CVC+ G CT VD E A L CD + PG C PG + C
Sbjct: 707 CVCNLGYEAGASGKDCTDVD-ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765
Query: 334 --DE-------NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN- 381
DE + C NL YTCKC G + D G C D + + C N
Sbjct: 766 DVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNL 825
Query: 382 ------TRCVNVVG---GYVCQ-------CLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
+ C +G G C+ C G+ R C +V+ECE C +
Sbjct: 826 QGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGR 884
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC-VNIDGGFRCECFTENCE 484
C NT GS+ C C +G D + VD E C V + G +R + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCC--CS 942
Query: 485 LSCSW 489
+ W
Sbjct: 943 IGAVW 947
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 35/213 (16%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-- 357
C R DP C V+ C N C+N + C+C +G D
Sbjct: 846 CERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 905
Query: 358 GLTCQDV-----------DECQ--------------EAGGLHGHHCHSNTRCVNVVGGYV 392
G C DV DEC G + G C + ++ +
Sbjct: 906 GRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASL 965
Query: 393 CQCLGGYTRKDKFN----CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-- 446
C G+ +D + +V+EC+ C C NT GS+ C C G+ D
Sbjct: 966 CPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC C CVN G F CECF
Sbjct: 1025 NCTDIDECRISPDLCGQGT-CVNTPGSFECECF 1056
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/225 (28%), Positives = 82/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGVDYCNM 329
G RF C G QC AC C P + G C GV +
Sbjct: 61 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSC-GV---SR 116
Query: 330 GHSCDENATCMNLNT--KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
G C + +CMN T +C C +G+ G + Q + C + G +G C RC V
Sbjct: 117 GSGC--SVSCMNGGTCRGASCLCQKGYTGT-VCGQPI--C-DRGCHNGGRCIGPNRCACV 170
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHAD-AVCTNTPG---SYTCR------- 436
G QC Y F V + C+ G A+C T G C
Sbjct: 171 YGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 230
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + +T C VDEC C + CVN+ G F C C
Sbjct: 231 PCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRC 274
Score = 49.2 bits (112), Expect = 5e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ C C GY +T C +DEC+ S C
Sbjct: 1563 DIDECQELPGLCQGGD-CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGT 1620
Query: 467 CVNIDGGFRCECFTENCELS 486
C N G + C C E +++
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVN 1640
Score = 48.4 bits (110), Expect = 8e-05
Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 23/226 (10%)
Query: 184 KLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEIT-CRPV-ECDRA 241
KL A + R E + C + +G+ + C+R + T C + ECDR
Sbjct: 1796 KLSPGGACVGRNECREIPNVCSHGDCMDTEGS-YMCLCHRGFQASADQTLCMDIDECDRQ 1854
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECV---CHDGNMQCTRVDPEL 298
C N CL C + +G+ EC V C G+ C
Sbjct: 1855 PCGNGTCKNIIGSYNCL--CFPGFVVTHNGDCVDFDECTTLVGQVCRFGH--CLNTAGSF 1910
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
C C + + G K C + C ++ +C TC NL + C C GFQ
Sbjct: 1911 HCL---CQDGFELTADG---KNCVDTNECLSLAGTCLPG-TCQNLEGSFRCICPPGFQVQ 1963
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C D+DEC E L C T C N G + C C G+ D
Sbjct: 1964 SDHCIDIDECSEEPNL----CLFGT-CTNSPGSFQCLCPPGFVLSD 2004
Score = 44.0 bits (99), Expect = 0.002
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ T C+D+DEC H C
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDEC----STHSSICGPG 1619
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N +G Y C C Y + NC+++
Sbjct: 1620 T-CYNTLGNYTCVCPAEYLQVNGGNNCMDM 1648
Score = 42.3 bits (95), Expect = 0.005
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 350 CNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C +GF + T CQDVDECQ GL C + CVN+VG + C+C G+ D
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGL----CQGGS-CVNMVGSFHCRCPVGHRLSD 282
Score = 33.1 bits (72), Expect = 3.2
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C +VDEC+ C + C N GS+ CRC G+
Sbjct: 245 CQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGH 278
>X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein.
Length = 754
Score = 142 bits (343), Expect = 5e-33
Identities = 76/219 (34%), Positives = 107/219 (48%), Gaps = 28/219 (12%)
Query: 281 ECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE--C-C----------KFC 321
EC C +G C +D P + CD Q ++PGE C C K C
Sbjct: 513 ECSCSEGYALMPDGRSCADIDECENNPDI-CDGGQCTNIPGEYRCLCYDGFMASMDMKTC 571
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHCH 379
V+ C++ + C N + C C G+ G T C DVDEC+ + H+C
Sbjct: 572 IDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECE----IGAHNCD 627
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C+N+ G + C C G+ C++ DEC TH C +A C NTPGSY C C +
Sbjct: 628 MHASCLNIPGSFKCSCREGWIGNG-IKCIDRDECSNGTHQCSINAQCVNTPGSYRCACSE 686
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+TC VDEC E + C + +C+N+ G +RCEC
Sbjct: 687 GFTGDGFTCSDVDECAENINLC-ENGQCLNVPGAYRCEC 724
Score = 140 bits (340), Expect = 1e-32
Identities = 90/303 (29%), Positives = 132/303 (43%), Gaps = 22/303 (7%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C N + G + + +C C G E++ +C D EC
Sbjct: 393 GYESGFMMMKNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINEC 452
Query: 244 K--NPVLHPGECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPEL 298
+ + G+C QC +R + EC+ +G + QCT +
Sbjct: 453 SLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSY 512
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-- 356
C C G + C +D C + C N+ +Y C C GF
Sbjct: 513 ECS---CSEGYALMPDG---RSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASM 566
Query: 357 DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEG 415
D TC DV+EC L+ + C C N G ++C C GY+ +K C +VDECE
Sbjct: 567 DMKTCIDVNECD----LNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI 621
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
H C A C N PGS+ C CR+G+ G+G C+ DEC+ G+H C +A+CVN G +R
Sbjct: 622 GAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDRDECSNGTHQCSINAQCVNTPGSYR 681
Query: 476 CEC 478
C C
Sbjct: 682 CAC 684
Score = 113 bits (272), Expect = 2e-24
Identities = 50/122 (40%), Positives = 68/122 (55%), Gaps = 7/122 (5%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C +G H+CD +A+C+N+ + C C +G+ G+G+ C D DEC H C
Sbjct: 613 CTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDRDECSNGT----HQCS 668
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
N +CVN G Y C C G+T D F C +VDEC N + C + C N PG+Y C C
Sbjct: 669 INAQCVNTPGSYRCACSEGFTG-DGFTCSDVDECAENINLCE-NGQCLNVPGAYRCECEM 726
Query: 440 GY 441
G+
Sbjct: 727 GF 728
Score = 111 bits (266), Expect = 1e-23
Identities = 58/166 (34%), Positives = 78/166 (46%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C +D C TC+N + C C G + C D++EC + L
Sbjct: 402 KNCMDIDGCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNL--- 458
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C N +CVN++G Y C C GY D+ C ++DEC GC D CTN+ GSY C
Sbjct: 459 -CR-NGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGC--DTQCTNSEGSYEC 514
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +GY DG +C +DEC C +C NI G +RC C+
Sbjct: 515 SCSEGYALMPDGRSCADIDECENNPDICD-GGQCTNIPGEYRCLCY 559
Score = 94.3 bits (224), Expect = 1e-18
Identities = 83/283 (29%), Positives = 122/283 (43%), Gaps = 40/283 (14%)
Query: 214 GATWQRDCNRC----SCVHGEITCRPVEC-DRAECKNPVLHPGECCPTCLRQCL-LWGNL 267
GA W C RC +C G + V C D EC+ + PG CP +C+ G+
Sbjct: 173 GAAWGSPCERCELDTACPRGLARIKGVTCEDVNECE---VFPG-VCPN--GRCVNSKGSF 226
Query: 268 YEHGERFAPKECAECVCHDGNM-QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDY 326
+ + VC D M QC E C P +F + CC G +
Sbjct: 227 HCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIH---PVPGKFRMDACCCAV--GAAW 281
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLT----CQDVDECQEAGGLHGHHCHS 380
G C+E + C GF +GD LT +D++EC+ G+ C +
Sbjct: 282 ---GTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGM----C-T 333
Query: 381 NTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+C N +G + C+C G+ ++ NC ++DEC + C +C NTPGS+ C C +
Sbjct: 334 YGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLC-GSGICVNTPGSFECECFE 392
Query: 440 GYEGDGY----TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE G+ CM +D C C CVN +G F+C+C
Sbjct: 393 GYE-SGFMMMKNCMDIDGCERNPLLC-RGGTCVNTEGSFQCDC 433
Score = 79.4 bits (187), Expect = 4e-14
Identities = 50/160 (31%), Positives = 68/160 (42%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ D G C D+DEC L N
Sbjct: 17 INECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDEC-----LVNRLLCDN 71
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C GY R + C +++ECE N C + C N GS+ C C G
Sbjct: 72 GLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNP--C-VNGACRNNLGSFNCECSPG 128
Query: 441 YEGDGYTCMHVDECTEGSHTCHHSARC-VNIDGG-FRCEC 478
+ + +D +RC VNI+G + EC
Sbjct: 129 SKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSEC 168
Score = 79.4 bits (187), Expect = 4e-14
Identities = 40/89 (44%), Positives = 49/89 (55%), Gaps = 7/89 (7%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C D C+ G H C NA C+N Y C C++GF GDG TC DVDEC E L C
Sbjct: 654 CIDRDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINL----CE 709
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNC 407
N +C+NV G Y C+C G+T D +C
Sbjct: 710 -NGQCLNVPGAYRCECEMGFTPASDSRSC 737
Score = 79.0 bits (186), Expect = 5e-14
Identities = 50/134 (37%), Positives = 66/134 (49%), Gaps = 15/134 (11%)
Query: 348 CKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-N 406
C G DG +D++EC L C +N C N+ G Y C C GY N
Sbjct: 4 CSSGVGITVDG---RDINEC----ALDPDIC-ANGICENLRGSYRCNCNSGYEPDASGRN 55
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHS 464
C+++DEC N C + +C NTPGSY+C C GY + TC ++EC S+ C +
Sbjct: 56 CIDIDECLVNRLLCD-NGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE--SNPCVNG 112
Query: 465 ARCVNIDGGFRCEC 478
A C N G F CEC
Sbjct: 113 A-CRNNLGSFNCEC 125
Score = 62.5 bits (145), Expect = 5e-09
Identities = 53/183 (28%), Positives = 74/183 (40%), Gaps = 33/183 (18%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHC 378
C +D C + +N C N Y+C C G F+ + TC+D++EC+ + C
Sbjct: 56 CIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECE------SNPC 109
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKD---------KFNC---VEVDECEGNTHGCHADAVC 426
N C N +G + C+C G K C ++ CE N +G + C
Sbjct: 110 -VNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSEC 168
Query: 427 TNTPGS---YTC-RC-------RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
T G+ C RC R G TC V+EC C + RCVN G F
Sbjct: 169 CATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVC-PNGRCVNSKGSFH 227
Query: 476 CEC 478
CEC
Sbjct: 228 CEC 230
Score = 55.2 bits (127), Expect = 7e-07
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSAR 466
+++EC+ C C NT GS+ CRC G+ D C +DEC C S
Sbjct: 321 DINECKAFPGMC-TYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCG-SGI 378
Query: 467 CVNIDGGFRCECF 479
CVN G F CECF
Sbjct: 379 CVNTPGSFECECF 391
Score = 35.9 bits (79), Expect = 0.45
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQ 362
C VD C + EN C+N+ Y C+C GF D +CQ
Sbjct: 695 CSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ 738
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 142 bits (343), Expect = 5e-33
Identities = 94/302 (31%), Positives = 126/302 (41%), Gaps = 20/302 (6%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C + + G D + +C C G E+T + C D EC
Sbjct: 1065 GYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDEC 1124
Query: 244 K-NPVLHP-GECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELAC 300
+ L P G+C QC +R + EC +G ++ E
Sbjct: 1125 SLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GS 1183
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DG 358
R C G C VD C + C N+ + C C GF D
Sbjct: 1184 YRCSCGQGYSLMPDGRACA---DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDM 1240
Query: 359 LTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGN 416
TC DVDEC L+ H C H + C N G +VC C GY RK C +VDECE
Sbjct: 1241 RTCVDVDECD----LNPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1294
Query: 417 THGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
H C + A C N PGS++CRC G+ GDG+ C +DEC H C C+N+ G +RC
Sbjct: 1295 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECISQEHRCSPRGDCLNVPGSYRC 1354
Query: 477 EC 478
C
Sbjct: 1355 TC 1356
Score = 140 bits (338), Expect = 2e-32
Identities = 65/160 (40%), Positives = 85/160 (53%), Gaps = 8/160 (5%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHC 378
C VD C++ + C N + C C G+ G T C DVDEC E GG H+C
Sbjct: 1243 CVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC-EVGG---HNC 1298
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ C+N+ G + C+CL G+ D F C ++DEC H C C N PGSY C CR
Sbjct: 1299 DSHASCLNIPGSFSCRCLPGWVG-DGFECHDLDECISQEHRCSPRGDCLNVPGSYRCTCR 1357
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+ C DEC E C + +C+N GG+RCEC
Sbjct: 1358 QGFAGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCEC 1396
Score = 124 bits (300), Expect = 8e-28
Identities = 63/166 (37%), Positives = 80/166 (48%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C VD C TC N + Y C+C G + G C+D+DEC + GL H
Sbjct: 1074 KNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH 1133
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+CVNV+G + C C G+ + D+ CV+++EC GC D C NT GSY C
Sbjct: 1134 G-----QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRC 1186
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C GY DG C VDEC E C C N+ GG RC C+
Sbjct: 1187 SCGQGYSLMPDGRACADVDECEENPRVCDQG-HCTNMPGGHRCLCY 1231
Score = 115 bits (277), Expect = 5e-25
Identities = 68/178 (38%), Positives = 91/178 (51%), Gaps = 16/178 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C + H C C+N+ Y C C QGF GDG C+D DEC E L C
Sbjct: 1326 CHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL----C- 1380
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
N +C+N GGY C+C G+ +D C +VDEC +GN C A C N PG + C C
Sbjct: 1381 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL--C-AFGSCENLPGMFRCIC 1437
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRV 493
GYE D G C ++EC + + C + C+N G + C C ++ EL+ S G V
Sbjct: 1438 NGGYELDRGGGNCTDINECADPVN-CINGV-CINTPGSYLCSC-PQDFELNPSGVGCV 1492
Score = 114 bits (275), Expect = 8e-25
Identities = 75/209 (35%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 278 ECAEC--VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE VC +G C D C C P +S+ C D C++GH C +
Sbjct: 2094 ECAENPGVCTNG--VCVNTDGSFRCE---C--PFGYSLDFTGIN-CVDTDECSVGHPCGQ 2145
Query: 336 NATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
TC N+ + C C GF+ G +TC+D+DEC L CH N G Y+C
Sbjct: 2146 G-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCH------NTEGSYLCT 2198
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAV-CTNTPGSYTCRCRDGYE---GDGYTCM 449
C GYT R+D C +VDEC CHA + C N G++ C C G G G C
Sbjct: 2199 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2258
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC C + RCVN G FRC+C
Sbjct: 2259 DDNECHAQPDLCVNG-RCVNTAGSFRCDC 2286
Score = 111 bits (267), Expect = 7e-24
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 14/144 (9%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C C +G+ + DG TC+D+DEC H+C CVN VG + C+C
Sbjct: 2427 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS----RQHNCQF--LCVNTVGAFTCRCP 2480
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDEC 454
G+T+ + C + DEC C A C NTPGS+ C C G+ G+ C V+EC
Sbjct: 2481 PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2539
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
+G H C H C N GG+RC C
Sbjct: 2540 -DGPHRCQHG--CQNQLGGYRCSC 2560
Score = 111 bits (266), Expect = 1e-23
Identities = 59/160 (36%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC GH C
Sbjct: 2092 VNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-----GHPCGQG 2146
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+GG+ C C G+ C ++DEC N C C NT GSY C C GY
Sbjct: 2147 T-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGY 2203
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
DG C VDEC +G CH C N+ G F C C
Sbjct: 2204 TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2243
Score = 108 bits (260), Expect = 5e-23
Identities = 94/311 (30%), Positives = 125/311 (40%), Gaps = 39/311 (12%)
Query: 193 SRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD------RAECKNP 246
S E+C+ +C + G G T D N C G C C R EC
Sbjct: 851 SPCERCEIDPAC-ARGFARMTGVTCD-DVNECESFPG--VCPNGRCVNTAGSFRCECPEG 906
Query: 247 VLHPGE---CCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDG---NMQCTRV-DPEL 298
++ C L C L + E G K + C C G ++C DPE
Sbjct: 907 LMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPES 966
Query: 299 A-----CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
CPR + F + G F V+ C + + TC N + C C G
Sbjct: 967 LEFASLCPRGLGFASRDF-LSGR--PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGG 1023
Query: 354 FQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF--NCVE 409
F D C D+DEC+ + L C T CVN G + C+C GY NC++
Sbjct: 1024 FALDAQERNCTDIDECRISPDL----CGQGT-CVNTPGSFECECFPGYESGFMLMKNCMD 1078
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARC 467
VDEC + C CTNT GSY C+C G+E G C +DEC+ C H +C
Sbjct: 1079 VDECARDPLLCRG-GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQC 1136
Query: 468 VNIDGGFRCEC 478
VN+ G F+C C
Sbjct: 1137 VNVIGAFQCSC 1147
Score = 107 bits (256), Expect = 2e-22
Identities = 69/183 (37%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-- 359
R C+ V GEC VD C C + C+N+ Y C+C GFQ
Sbjct: 439 RCECNVGYTQDVRGECID----VDECTSS-PC-HHGDCVNIPGTYHCRCYPGFQATPTRQ 492
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTH 418
C DVDEC +GGL CH RCVN G + C C G+ D NCV+ +EC +T
Sbjct: 493 ACVDVDECIVSGGL----CHLG-RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 547
Query: 419 GCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
C + VC N GS++C C+ G+ G+ CM +DEC T G H C N +G FR
Sbjct: 548 -C-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH---CTNTEGSFR 602
Query: 476 CEC 478
C+C
Sbjct: 603 CQC 605
Score = 103 bits (247), Expect = 2e-21
Identities = 67/205 (32%), Positives = 85/205 (41%), Gaps = 19/205 (9%)
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG--VDYCNM-GHSCDEN 336
AEC C G R + CP LP + P G VD C M H C +
Sbjct: 2329 AECCCGGGRGWGPRCE---LCP-LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AH 2383
Query: 337 ATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N + C C G+ D TC D+DEC + C C N G ++C
Sbjct: 2384 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP----KPC--TFLCKNTKGSFLCS 2437
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C GY +D C ++DEC H C +C NT G++TCRC G+ C DE
Sbjct: 2438 CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDNDE 2495
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
C+ C C N G FRCEC
Sbjct: 2496 CSAQPGPCGAHGHCHNTPGSFRCEC 2520
Score = 100 bits (239), Expect = 2e-20
Identities = 56/161 (34%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSN 381
+D C + N C+N + C+C GF + L C+DVDEC G C N
Sbjct: 1729 IDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC----GSRESPCQQN 1784
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDG 440
C+N+ G Y C+C GY CV +EC + C H D C +T GSY C C G
Sbjct: 1785 ADCINIPGSYRCKCTRGYKLSPGGACVGQNECREIPNVCSHGD--CMDTEGSYMCLCHRG 1842
Query: 441 YE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
++ D CM +DEC C + C NI G + C CF
Sbjct: 1843 FQASADQTLCMDIDECDR--QPCGNGT-CKNIIGSYNCLCF 1880
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/159 (35%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNT 382
+D C + N C+ + Y C+CN G+ D C DVDEC + HG
Sbjct: 416 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD------ 469
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN+ G Y C+C G+ + CV+VDEC + CH C NT GS+ C C G+
Sbjct: 470 -CVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAGF 527
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E DG C+ +EC S C + C+N DG F C C
Sbjct: 528 ELSPDGKNCVDHNECAT-STMCVNGV-CLNEDGSFSCLC 564
Score = 95.5 bits (227), Expect = 5e-19
Identities = 70/220 (31%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 265 GNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV 324
G L E R K+ EC N Q V+ A C P F+ + C
Sbjct: 2441 GYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGA---FTCRCPPGFTQHHQACF---DN 2493
Query: 325 DYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
D C+ C + C N + C+C+QGF G C+DV+EC H C
Sbjct: 2494 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGP-----HRCQHG 2548
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N +GGY C C G+T+ ++ CV+ +EC + C A C NT G + C C G
Sbjct: 2549 --CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC-GSASCRNTLGGFRCVCPSG 2605
Query: 441 YEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++ D C VDEC C +S C N GGF C C
Sbjct: 2606 FDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGC 2643
Score = 94.3 bits (224), Expect = 1e-18
Identities = 56/178 (31%), Positives = 81/178 (45%), Gaps = 13/178 (7%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQ 362
C+ P F+ C VD C S C +NA C+N+ Y CKC +G++ G C
Sbjct: 1753 CECPAGFNY-NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACV 1811
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
+EC+E + C S+ C++ G Y+C C G+ D+ C+++DEC+ G
Sbjct: 1812 GQNECREIPNV----C-SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG-- 1864
Query: 422 ADAVCTNTPGSYTCRCRDGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C N GSY C C G+ C+ DECT C+N G F C C
Sbjct: 1865 -NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLC 1921
Score = 91.1 bits (216), Expect = 1e-17
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGDGLTCQDVDECQEAGGLHGH 376
C +D C+ C N TC N+ Y C C GF GD C D DEC L G
Sbjct: 1852 CMDIDECDR-QPCG-NGTCKNIIGSYNCLCFPGFVVTHNGD---CVDFDECTT---LVGQ 1903
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N G + C C G+ D NCV+ +EC C C N GS+ C
Sbjct: 1904 VCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPGTCQNLEGSFRC 1961
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ C+ +DEC+E + C C N G F+C C
Sbjct: 1962 ICPPGFQVQSDHCIDIDECSEEPNLCLFGT-CTNSPGSFQCLC 2003
Score = 90.2 bits (214), Expect = 2e-17
Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHH 377
C +D C + TC+N + C+C G++ + C DVDEC L
Sbjct: 1033 CTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLL---- 1088
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C T C N G Y CQC G+ K C ++DEC + G C N G++ C
Sbjct: 1089 CRGGT-CTNTDGSYKCQCPPGHELTAKGTACEDIDEC-SLSDGLCPHGQCVNVIGAFQCS 1146
Query: 437 CRDGYEG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C+ ++EC + C C+N +G +RC C
Sbjct: 1147 CHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRCSC 1188
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCH 421
D+DEC E + C +N C+N +G + C+C G+ C +VDEC C
Sbjct: 1728 DIDECGEIPAI----C-ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1782
Query: 422 ADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+A C N PGSY C+C GY+ G C+ +EC E + C H C++ +G + C C
Sbjct: 1783 QNADCINIPGSYRCKCTRGYKLSPGGACVGQNECREIPNVCSH-GDCMDTEGSYMCLC 1839
Score = 82.6 bits (195), Expect = 4e-15
Identities = 58/169 (34%), Positives = 76/169 (44%), Gaps = 21/169 (12%)
Query: 284 CHDGN---MQCTRVDPELACPRLP----CDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
CHD + Q R P C +P C Q F+ G FC D C +N
Sbjct: 1326 CHDLDECISQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGF---FCEDRDECAENVDLCDN 1382
Query: 337 ATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N Y C+C GF D CQDVDEC + G+ C + C N+ G + C
Sbjct: 1383 GQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-----GNLCAFGS-CENLPGMFRCI 1436
Query: 395 CLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
C GGY + NC +++EC + C + VC NTPGSY C C +E
Sbjct: 1437 CNGGYELDRGGGNCTDINECADPVN-C-INGVCINTPGSYLCSCPQDFE 1483
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/165 (35%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ G C DVDEC L+ C N
Sbjct: 690 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC----ALNSLLC-DN 744
Query: 382 TRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C G+ +D C +VDEC + C VC N GSYTC+C G
Sbjct: 745 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--C-VSGVCRNLAGSYTCKCGPG 801
Query: 441 YEGD--GYTCMHVDECTEGSHTCH---HSARC-VNIDG-GFRCEC 478
D G C+ + T+G TC +RC VN+ G R EC
Sbjct: 802 SRLDPSGTFCL---DSTKG--TCWLKIQESRCEVNLQGASLRSEC 841
Score = 77.8 bits (183), Expect = 1e-13
Identities = 65/234 (27%), Positives = 94/234 (40%), Gaps = 37/234 (15%)
Query: 240 RAEC-KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R +C + L PG C +C N+ HG+ + C+CH G C
Sbjct: 1795 RCKCTRGYKLSPGGAC-VGQNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCM 1853
Query: 293 RVDPELACPRLPCDPPQQFSVPGE--CCKF----------CPGVDYCN--MGHSCDENAT 338
+D C R PC ++ G C F C D C +G C
Sbjct: 1854 DIDE---CDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGH 1909
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C+N + C C GF+ DG C D +EC G C T C N+ G + C C
Sbjct: 1910 CLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT----CLPGT-CQNLEGSFRCICP 1964
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTC 448
G+ + +C+++DEC + C CTN+PGS+ C C G+ +G+ C
Sbjct: 1965 PGFQVQSD-HCIDIDECSEEPNLC-LFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2016
Score = 75.8 bits (178), Expect = 5e-13
Identities = 60/207 (28%), Positives = 84/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT +C + GE EC CH G+ C + C C P
Sbjct: 429 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD--CVNIPGTYHCR---CYP 483
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q + + C VD C + C+N + C CN GF+ DG C D +
Sbjct: 484 GFQATPTRQACV---DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHN 540
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ + C+++DEC+ T G +
Sbjct: 541 ECATST-----MC-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ--TPGICVNG 592
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCM 449
CTNT GS+ C+C G DG C+
Sbjct: 593 HCTNTEGSFRCQCLGGLAVGTDGRVCV 619
Score = 73.3 bits (172), Expect = 2e-12
Identities = 44/122 (36%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C+ H C C N Y C C QGF Q VDE + A L C S
Sbjct: 2533 CEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGS 2588
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N +GG+ C C G+ C +VDEC G C C NTPG + C C
Sbjct: 2589 AS-CRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGCPQ 2645
Query: 440 GY 441
GY
Sbjct: 2646 GY 2647
Score = 72.5 bits (170), Expect = 4e-12
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 35/190 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGG 372
G K C VD C + +N C N Y+C C GF D C+DVDEC +
Sbjct: 723 GASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSS-- 780
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD----------KFNC---VEVDECEGNTHG 419
C S C N+ G Y C+C G +R D K C ++ CE N G
Sbjct: 781 ----PCVSGV-CRNLAGSYTCKC-GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQG 834
Query: 420 CHADAVCTNTPGS---YTCR-------CRDGY-EGDGYTCMHVDECTEGSHTCHHSARCV 468
+ C T G+ C C G+ G TC V+EC C + RCV
Sbjct: 835 ASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCV 893
Query: 469 NIDGGFRCEC 478
N G FRCEC
Sbjct: 894 NTAGSFRCEC 903
Score = 67.3 bits (157), Expect = 2e-10
Identities = 43/126 (34%), Positives = 58/126 (46%), Gaps = 13/126 (10%)
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNV 387
G+ C+ + C +GFQ + +T +D+DECQE GL C CVN
Sbjct: 1535 GNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL----CQGGD-CVNT 1589
Query: 388 VGGYVCQCLGGYTRKDKFN-CVEVDECEGNTH-GCHADAVCTNTPGSYTCRCRDGY--EG 443
G + C+C GY + C ++DEC +TH G C NT G+YTC C Y
Sbjct: 1590 FGSFQCECPPGYHLSEHTRICEDIDEC--STHSGICGPGTCYNTLGNYTCVCPAEYLQVN 1647
Query: 444 DGYTCM 449
G CM
Sbjct: 1648 GGNNCM 1653
Score = 65.7 bits (153), Expect = 5e-10
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C++ C N Y C C G+ + DG C+DVDEC + C
Sbjct: 2171 CEDIDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ----QDC 2225
Query: 379 HSN-TRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC 435
H+ C N++G + C C G C + +EC C + C NT GS+ C
Sbjct: 2226 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFRC 2284
Query: 436 RCRDGYE 442
C +G++
Sbjct: 2285 DCDEGFQ 2291
Score = 59.7 bits (138), Expect = 3e-08
Identities = 31/71 (43%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCV 468
+D C T+ C + C TP SY C C GY D C+ VDECT S CHH CV
Sbjct: 416 IDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGD-CV 471
Query: 469 NIDGGFRCECF 479
NI G + C C+
Sbjct: 472 NIPGTYHCRCY 482
Score = 56.8 bits (131), Expect = 2e-07
Identities = 65/229 (28%), Positives = 84/229 (36%), Gaps = 39/229 (17%)
Query: 278 ECA-ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA +C +G C D +C C P + G +C +D C C N
Sbjct: 541 ECATSTMCVNG--VCLNEDGSFSCL---CKPGFLLAPGGH---YCMDIDECQTPGIC-VN 591
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDV---DECQ---EAGG----LHGHHCHSNTRC 384
C N + C+C G DG C D C E G G S C
Sbjct: 592 GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 651
Query: 385 VNVVGGY--VCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTPG 431
N G+ CQ C + + + C +++EC + C A+ VC N G
Sbjct: 652 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVC-ANGVCENLRG 710
Query: 432 SYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SY C C GYE G C VDEC S C + C N G + C C
Sbjct: 711 SYRCVCNLGYEAGASGKDCTDVDECALNSLLC-DNGWCQNSPGSYSCSC 758
Score = 55.6 bits (128), Expect = 5e-07
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQ 362
C PQ F+ + + C + C + +A+C N + C C GF D CQ
Sbjct: 2558 CSCPQGFTQHSQWAQ-CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2616
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
DVDEC G G +S C N GG++C C GY R + +CV
Sbjct: 2617 DVDEC---AGRRGPCSYS---CANTPGGFLCGCPQGYFRAGQGHCV 2656
Score = 54.4 bits (125), Expect = 1e-06
Identities = 67/245 (27%), Positives = 88/245 (35%), Gaps = 41/245 (16%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSC- 333
CVC+ G CT VD E A L CD + PG C PG + C
Sbjct: 714 CVCNLGYEAGASGKDCTDVD-ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 772
Query: 334 --DE-------NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN- 381
DE + C NL YTCKC G + D G C D + + C N
Sbjct: 773 DVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNL 832
Query: 382 ------TRCVNVVG---GYVCQ-------CLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
+ C +G G C+ C G+ R C +V+ECE C +
Sbjct: 833 QGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGR 891
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC-VNIDGGFRCECFTENCE 484
C NT GS+ C C +G D + VD E C V + G +R + C
Sbjct: 892 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCC--CS 949
Query: 485 LSCSW 489
+ W
Sbjct: 950 IGAVW 954
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 35/213 (16%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-- 357
C R DP C V+ C N C+N + C+C +G D
Sbjct: 853 CERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 912
Query: 358 GLTCQDV-----------DECQ--------------EAGGLHGHHCHSNTRCVNVVGGYV 392
G C DV DEC G + G C + ++ +
Sbjct: 913 GRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASL 972
Query: 393 CQCLGGYTRKDKFN----CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-- 446
C G+ +D + +V+EC+ C C NT GS+ C C G+ D
Sbjct: 973 CPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER 1031
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC C CVN G F CECF
Sbjct: 1032 NCTDIDECRISPDLCGQGT-CVNTPGSFECECF 1063
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/225 (28%), Positives = 82/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGVDYCNM 329
G RF C G QC AC C P + G C GV +
Sbjct: 68 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSC-GV---SR 123
Query: 330 GHSCDENATCMNLNT--KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
G C + +CMN T +C C +G+ G + Q + C + G +G C RC V
Sbjct: 124 GSGC--SVSCMNGGTCRGASCLCQKGYTGT-VCGQPI--C-DRGCHNGGRCIGPNRCACV 177
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHAD-AVCTNTPG---SYTCR------- 436
G QC Y F V + C+ G A+C T G C
Sbjct: 178 YGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 237
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + +T C VDEC C + CVN+ G F C C
Sbjct: 238 PCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRC 281
Score = 48.8 bits (111), Expect = 6e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ C C GY +T C +DEC+ S C
Sbjct: 1570 DIDECQELPGLCQGGD-CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGIC-GPGT 1627
Query: 467 CVNIDGGFRCECFTENCELS 486
C N G + C C E +++
Sbjct: 1628 CYNTLGNYTCVCPAEYLQVN 1647
Score = 48.0 bits (109), Expect = 1e-04
Identities = 48/171 (28%), Positives = 62/171 (36%), Gaps = 20/171 (11%)
Query: 237 ECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECV---CHDGNMQCTR 293
ECDR C N CL C + +G+ EC V C G+ C
Sbjct: 1857 ECDRQPCGNGTCKNIIGSYNCL--CFPGFVVTHNGDCVDFDECTTLVGQVCRFGH--CLN 1912
Query: 294 VDPELACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQ 352
C C + + G K C + C ++ +C TC NL + C C
Sbjct: 1913 TAGSFHCL---CQDGFELTADG---KNCVDTNECLSLAGTCLPG-TCQNLEGSFRCICPP 1965
Query: 353 GFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
GFQ C D+DEC E L C T C N G + C C G+ D
Sbjct: 1966 GFQVQSDHCIDIDECSEEPNL----CLFGT-CTNSPGSFQCLCPPGFVLSD 2011
Score = 44.8 bits (101), Expect = 0.001
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ T C+D+DEC G+ C
Sbjct: 1571 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGI----CGPG 1626
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N +G Y C C Y + NC+++
Sbjct: 1627 T-CYNTLGNYTCVCPAEYLQVNGGNNCMDM 1655
Score = 42.3 bits (95), Expect = 0.005
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 350 CNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C +GF + T CQDVDECQ GL C + CVN+VG + C+C G+ D
Sbjct: 239 CRRGFIPNIHTGACQDVDECQAVPGL----CQGGS-CVNMVGSFHCRCPVGHRLSD 289
Score = 33.1 bits (72), Expect = 3.2
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C +VDEC+ C + C N GS+ CRC G+
Sbjct: 252 CQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGH 285
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 141 bits (342), Expect = 6e-33
Identities = 94/302 (31%), Positives = 126/302 (41%), Gaps = 20/302 (6%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAEC 243
G E+ ++ C C + + G D + +C C G E+T + C D EC
Sbjct: 1058 GYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDEC 1117
Query: 244 K-NPVLHP-GECCPTC-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELAC 300
+ L P G+C QC +R + EC +G ++ E
Sbjct: 1118 SLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTE-GS 1176
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DG 358
R C G C VD C + C N+ + C C GF D
Sbjct: 1177 YRCSCGQGYSLMPDGRACA---DVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDM 1233
Query: 359 LTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGN 416
TC DVDEC L+ H C H + C N G +VC C GY RK C +VDECE
Sbjct: 1234 RTCVDVDECD----LNPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSDVDECEVG 1287
Query: 417 THGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
H C + A C N PGS++CRC G+ GDG+ C +DEC H C C+N+ G +RC
Sbjct: 1288 GHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRC 1347
Query: 477 EC 478
C
Sbjct: 1348 TC 1349
Score = 140 bits (339), Expect = 1e-32
Identities = 65/160 (40%), Positives = 85/160 (53%), Gaps = 8/160 (5%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT-CQDVDECQEAGGLHGHHC 378
C VD C++ + C N + C C G+ G T C DVDEC E GG H+C
Sbjct: 1236 CVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC-EVGG---HNC 1291
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ C+N+ G + C+CL G+ D F C ++DEC H C C N PGSY C CR
Sbjct: 1292 DSHASCLNIPGSFSCRCLPGWVG-DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ GDG+ C DEC E C + +C+N GG+RCEC
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLC-DNGQCLNAPGGYRCEC 1389
Score = 123 bits (297), Expect = 2e-27
Identities = 63/166 (37%), Positives = 80/166 (48%), Gaps = 13/166 (7%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGH 376
K C VD C TC N + Y C+C G + G C+D+DEC + GL H
Sbjct: 1067 KNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH 1126
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+CVNV+G + C C G+ + D+ CV+++EC GC D C NT GSY C
Sbjct: 1127 G-----QCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRC 1179
Query: 436 RCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C GY DG C VDEC E C C N+ GG RC C+
Sbjct: 1180 SCGQGYSLMPDGRACADVDECEENPRVCDQG-HCTNMPGGHRCLCY 1224
Score = 115 bits (277), Expect = 5e-25
Identities = 68/178 (38%), Positives = 91/178 (51%), Gaps = 16/178 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C + H C C+N+ Y C C QGF GDG C+D DEC E L C
Sbjct: 1319 CHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDL----C- 1373
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
N +C+N GGY C+C G+ +D C +VDEC +GN C A C N PG + C C
Sbjct: 1374 DNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL--C-AFGSCENLPGMFRCIC 1430
Query: 438 RDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRV 493
GYE D G C ++EC + + C + C+N G + C C ++ EL+ S G V
Sbjct: 1431 NGGYELDRGGGNCTDINECADPVN-CINGV-CINTPGSYLCSC-PQDFELNPSGVGCV 1485
Score = 114 bits (275), Expect = 8e-25
Identities = 75/209 (35%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 278 ECAEC--VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE VC +G C D C C P +S+ C D C++GH C +
Sbjct: 2087 ECAENPGVCTNG--VCVNTDGSFRCE---C--PFGYSLDFTGIN-CVDTDECSVGHPCGQ 2138
Query: 336 NATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
TC N+ + C C GF+ G +TC+D+DEC L CH N G Y+C
Sbjct: 2139 G-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCH------NTEGSYLCT 2191
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAV-CTNTPGSYTCRCRDGYE---GDGYTCM 449
C GYT R+D C +VDEC CHA + C N G++ C C G G G C
Sbjct: 2192 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC C + RCVN G FRC+C
Sbjct: 2252 DDNECHAQPDLCVNG-RCVNTAGSFRCDC 2279
Score = 111 bits (267), Expect = 7e-24
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 14/144 (9%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C C +G+ + DG TC+D+DEC H+C CVN VG + C+C
Sbjct: 2420 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS----RQHNCQF--LCVNTVGAFTCRCP 2473
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDEC 454
G+T+ + C + DEC C A C NTPGS+ C C G+ G+ C V+EC
Sbjct: 2474 PGFTQHHQA-CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNEC 2532
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
+G H C H C N GG+RC C
Sbjct: 2533 -DGPHRCQHG--CQNQLGGYRCSC 2553
Score = 111 bits (266), Expect = 1e-23
Identities = 59/160 (36%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC GH C
Sbjct: 2085 VNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-----GHPCGQG 2139
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+GG+ C C G+ C ++DEC N C C NT GSY C C GY
Sbjct: 2140 T-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGY 2196
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
DG C VDEC +G CH C N+ G F C C
Sbjct: 2197 TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 2236
Score = 107 bits (258), Expect = 9e-23
Identities = 94/311 (30%), Positives = 125/311 (40%), Gaps = 39/311 (12%)
Query: 193 SRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD------RAECKNP 246
S E+C+ +C + G G T D N C G C C R EC
Sbjct: 844 SPCERCEIDPAC-ARGFARMTGVTCD-DVNECESFPG--VCPNGRCVNTAGSFRCECPEG 899
Query: 247 VLHPGE---CCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDG---NMQCTRV-DPEL 298
++ C L C L + E G K + C C G ++C DPE
Sbjct: 900 LMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPES 959
Query: 299 A-----CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
CPR + F + G F V+ C + + TC N + C C G
Sbjct: 960 LEFASLCPRGLGFASRDF-LSGR--PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGG 1016
Query: 354 FQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF--NCVE 409
F D C D+DEC+ + L C T CVN G + C+C GY NC++
Sbjct: 1017 FALDAQERNCTDIDECRISPDL----CGQGT-CVNTPGSFECECFPGYESGFMLMKNCMD 1071
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARC 467
VDEC + C CTNT GSY C+C G+E G C +DEC+ C H +C
Sbjct: 1072 VDECARDPLLCWG-GTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPH-GQC 1129
Query: 468 VNIDGGFRCEC 478
VN+ G F+C C
Sbjct: 1130 VNVIGAFQCSC 1140
Score = 107 bits (256), Expect = 2e-22
Identities = 69/183 (37%), Positives = 89/183 (48%), Gaps = 22/183 (12%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-- 359
R C+ V GEC VD C C + C+N+ Y C+C GFQ
Sbjct: 432 RCECNVGYTQDVRGECID----VDECTSS-PC-HHGDCVNIPGTYHCRCYPGFQATPTRQ 485
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVDECEGNTH 418
C DVDEC +GGL CH RCVN G + C C G+ D NCV+ +EC +T
Sbjct: 486 ACVDVDECIVSGGL----CHLG-RCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 419 GCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
C + VC N GS++C C+ G+ G+ CM +DEC T G H C N +G FR
Sbjct: 541 -C-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGH---CTNTEGSFR 595
Query: 476 CEC 478
C+C
Sbjct: 596 CQC 598
Score = 103 bits (247), Expect = 2e-21
Identities = 67/205 (32%), Positives = 85/205 (41%), Gaps = 19/205 (9%)
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG--VDYCNM-GHSCDEN 336
AEC C G R + CP LP + P G VD C M H C +
Sbjct: 2322 AECCCGGGRGWGPRCE---LCP-LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AH 2376
Query: 337 ATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N + C C G+ D TC D+DEC + C C N G ++C
Sbjct: 2377 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP----KPC--TFLCKNTKGSFLCS 2430
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C GY +D C ++DEC H C +C NT G++TCRC G+ C DE
Sbjct: 2431 CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDNDE 2488
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
C+ C C N G FRCEC
Sbjct: 2489 CSAQPGPCGAHGHCHNTPGSFRCEC 2513
Score = 99 bits (238), Expect = 2e-20
Identities = 56/161 (34%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSN 381
+D C + N C+N + C+C GF + L C+DVDEC G C N
Sbjct: 1722 IDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDEC----GSRESPCQQN 1777
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDG 440
C+N+ G Y C+C GY CV +EC + C H D C +T GSY C C G
Sbjct: 1778 ADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGD--CMDTEGSYMCLCHRG 1835
Query: 441 YE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
++ D CM +DEC C + C NI G + C CF
Sbjct: 1836 FQASADQTLCMDIDECDR--QPCGNGT-CKNIIGSYNCLCF 1873
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/159 (35%), Positives = 76/159 (47%), Gaps = 14/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNT 382
+D C + N C+ + Y C+CN G+ D C DVDEC + HG
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD------ 462
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN+ G Y C+C G+ + CV+VDEC + CH C NT GS+ C C G+
Sbjct: 463 -CVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAGF 520
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E DG C+ +EC S C + C+N DG F C C
Sbjct: 521 ELSPDGKNCVDHNECAT-STMCVNGV-CLNEDGSFSCLC 557
Score = 95.5 bits (227), Expect = 5e-19
Identities = 70/220 (31%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 265 GNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV 324
G L E R K+ EC N Q V+ A C P F+ + C
Sbjct: 2434 GYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGA---FTCRCPPGFTQHHQACF---DN 2486
Query: 325 DYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
D C+ C + C N + C+C+QGF G C+DV+EC H C
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGP-----HRCQHG 2541
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N +GGY C C G+T+ ++ CV+ +EC + C A C NT G + C C G
Sbjct: 2542 --CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC-GSASCRNTLGGFRCVCPSG 2598
Query: 441 YEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++ D C VDEC C +S C N GGF C C
Sbjct: 2599 FDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGC 2636
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/178 (31%), Positives = 81/178 (45%), Gaps = 13/178 (7%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQ 362
C+ P F+ C VD C S C +NA C+N+ Y CKC +G++ G C
Sbjct: 1746 CECPAGFNY-NSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACV 1804
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
+EC+E + C S+ C++ G Y+C C G+ D+ C+++DEC+ G
Sbjct: 1805 GRNECREIPNV----C-SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCG-- 1857
Query: 422 ADAVCTNTPGSYTCRCRDGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C N GSY C C G+ C+ DECT C+N G F C C
Sbjct: 1858 -NGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLC 1914
Score = 91.1 bits (216), Expect = 1e-17
Identities = 55/163 (33%), Positives = 71/163 (43%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGDGLTCQDVDECQEAGGLHGH 376
C +D C+ C N TC N+ Y C C GF GD C D DEC L G
Sbjct: 1845 CMDIDECDR-QPCG-NGTCKNIIGSYNCLCFPGFVVTHNGD---CVDFDECTT---LVGQ 1896
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N G + C C G+ D NCV+ +EC C C N GS+ C
Sbjct: 1897 VCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTC-LPGTCQNLEGSFRC 1954
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ C+ +DEC+E + C C N G F+C C
Sbjct: 1955 ICPPGFQVQSDHCIDIDECSEEPNLCLFGT-CTNSPGSFQCLC 1996
Score = 89.4 bits (212), Expect = 3e-17
Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHH 377
C +D C + TC+N + C+C G++ + C DVDEC L
Sbjct: 1026 CTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLL---- 1081
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C T C N G Y CQC G+ K C ++DEC + G C N G++ C
Sbjct: 1082 CWGGT-CTNTDGSYKCQCPPGHELTAKGTACEDIDEC-SLSDGLCPHGQCVNVIGAFQCS 1139
Query: 437 CRDGYEG--DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C+ ++EC + C C+N +G +RC C
Sbjct: 1140 CHAGFQSTPDRQGCVDINECRVQNGGC--DVHCINTEGSYRCSC 1181
Score = 85.0 bits (201), Expect = 7e-16
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCH 421
D+DEC E + C +N C+N +G + C+C G+ C +VDEC C
Sbjct: 1721 DIDECGEIPAI----C-ANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 422 ADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+A C N PGSY C+C GY+ G C+ +EC E + C H C++ +G + C C
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH-GDCMDTEGSYMCLC 1832
Score = 83.0 bits (196), Expect = 3e-15
Identities = 59/179 (32%), Positives = 79/179 (44%), Gaps = 23/179 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLP----CDPPQQFSVPGECCKFCPGVDY 326
G+ F + ECV + R P C +P C Q F+ G FC D
Sbjct: 1314 GDGFECHDLDECVSQEH-----RCSPRGDCLNVPGSYRCTCRQGFAGDGF---FCEDRDE 1365
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +N C+N Y C+C GF D CQDVDEC + G+ C + C
Sbjct: 1366 CAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQ-----GNLCAFGS-C 1419
Query: 385 VNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
N+ G + C C GGY + NC +++EC + C + VC NTPGSY C C +E
Sbjct: 1420 ENLPGMFRCICNGGYELDRGGGNCTDINECADPVN-C-INGVCINTPGSYLCSCPQDFE 1476
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/165 (35%), Positives = 75/165 (45%), Gaps = 23/165 (13%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSN 381
++ C + N C NL Y C CN G++ G C DVDEC L+ C N
Sbjct: 683 INECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC----ALNSLLC-DN 737
Query: 382 TRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C N G Y C C G+ +D C +VDEC + C VC N GSYTC+C G
Sbjct: 738 GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSP--C-VSGVCRNLAGSYTCKCGPG 794
Query: 441 YEGD--GYTCMHVDECTEGSHTCH---HSARC-VNIDG-GFRCEC 478
D G C+ + T+G TC +RC VN+ G R EC
Sbjct: 795 SRLDPSGTFCL---DSTKG--TCWLKIQESRCEVNLQGASLRSEC 834
Score = 77.8 bits (183), Expect = 1e-13
Identities = 65/234 (27%), Positives = 94/234 (40%), Gaps = 37/234 (15%)
Query: 240 RAEC-KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCT 292
R +C + L PG C +C N+ HG+ + C+CH G C
Sbjct: 1788 RCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCM 1846
Query: 293 RVDPELACPRLPCDPPQQFSVPGE--CCKF----------CPGVDYCN--MGHSCDENAT 338
+D C R PC ++ G C F C D C +G C
Sbjct: 1847 DIDE---CDRQPCGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVC-RFGH 1902
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C+N + C C GF+ DG C D +EC G C T C N+ G + C C
Sbjct: 1903 CLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGT----CLPGT-CQNLEGSFRCICP 1957
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTC 448
G+ + +C+++DEC + C CTN+PGS+ C C G+ +G+ C
Sbjct: 1958 PGFQVQSD-HCIDIDECSEEPNLC-LFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 75.8 bits (178), Expect = 5e-13
Identities = 60/207 (28%), Positives = 84/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT +C + GE EC CH G+ C + C C P
Sbjct: 422 GRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGD--CVNIPGTYHCR---CYP 476
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q + + C VD C + C+N + C CN GF+ DG C D +
Sbjct: 477 GFQATPTRQACV---DVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHN 533
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ + C+++DEC+ T G +
Sbjct: 534 ECATST-----MC-VNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ--TPGICVNG 585
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCM 449
CTNT GS+ C+C G DG C+
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCV 612
Score = 73.3 bits (172), Expect = 2e-12
Identities = 44/122 (36%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C V+ C+ H C C N Y C C QGF Q VDE + A L C S
Sbjct: 2526 CEDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGS 2581
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
+ C N +GG+ C C G+ C +VDEC G C C NTPG + C C
Sbjct: 2582 AS-CRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGCPQ 2638
Query: 440 GY 441
GY
Sbjct: 2639 GY 2640
Score = 72.5 bits (170), Expect = 4e-12
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 35/190 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGG 372
G K C VD C + +N C N Y+C C GF D C+DVDEC +
Sbjct: 716 GASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSS-- 773
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD----------KFNC---VEVDECEGNTHG 419
C S C N+ G Y C+C G +R D K C ++ CE N G
Sbjct: 774 ----PCVSGV-CRNLAGSYTCKC-GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQG 827
Query: 420 CHADAVCTNTPGS---YTCR-------CRDGY-EGDGYTCMHVDECTEGSHTCHHSARCV 468
+ C T G+ C C G+ G TC V+EC C + RCV
Sbjct: 828 ASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCV 886
Query: 469 NIDGGFRCEC 478
N G FRCEC
Sbjct: 887 NTAGSFRCEC 896
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/125 (32%), Positives = 57/125 (45%), Gaps = 11/125 (8%)
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNV 387
G+ C+ + C +GFQ + +T +D+DECQE GL C CVN
Sbjct: 1528 GNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL----CQGGD-CVNT 1582
Query: 388 VGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGD 444
G + C+C GY + C ++DEC ++ C C NT G+YTC C Y
Sbjct: 1583 FGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGTCYNTLGNYTCVCPAEYLQVNG 1641
Query: 445 GYTCM 449
G CM
Sbjct: 1642 GNNCM 1646
Score = 65.7 bits (153), Expect = 5e-10
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C++ C N Y C C G+ + DG C+DVDEC + C
Sbjct: 2164 CEDIDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ----QDC 2218
Query: 379 HSN-TRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC 435
H+ C N++G + C C G C + +EC C + C NT GS+ C
Sbjct: 2219 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFRC 2277
Query: 436 RCRDGYE 442
C +G++
Sbjct: 2278 DCDEGFQ 2284
Score = 59.7 bits (138), Expect = 3e-08
Identities = 31/71 (43%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCV 468
+D C T+ C + C TP SY C C GY D C+ VDECT S CHH CV
Sbjct: 409 IDICRHFTNLC-LNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECT--SSPCHHGD-CV 464
Query: 469 NIDGGFRCECF 479
NI G + C C+
Sbjct: 465 NIPGTYHCRCY 475
Score = 56.8 bits (131), Expect = 2e-07
Identities = 65/229 (28%), Positives = 84/229 (36%), Gaps = 39/229 (17%)
Query: 278 ECA-ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA +C +G C D +C C P + G +C +D C C N
Sbjct: 534 ECATSTMCVNG--VCLNEDGSFSCL---CKPGFLLAPGGH---YCMDIDECQTPGIC-VN 584
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDV---DECQ---EAGG----LHGHHCHSNTRC 384
C N + C+C G DG C D C E G G S C
Sbjct: 585 GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCC 644
Query: 385 VNVVGGY--VCQ-CLGGYTRKDKFNCV----------EVDECEGNTHGCHADAVCTNTPG 431
N G+ CQ C + + + C +++EC + C A+ VC N G
Sbjct: 645 ANPDHGFGEPCQLCPAKNSAEFQALCSSGLGITTDGRDINECALDPEVC-ANGVCENLRG 703
Query: 432 SYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SY C C GYE G C VDEC S C + C N G + C C
Sbjct: 704 SYRCVCNLGYEAGASGKDCTDVDECALNSLLC-DNGWCQNSPGSYSCSC 751
Score = 55.6 bits (128), Expect = 5e-07
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQ 362
C PQ F+ + + C + C + +A+C N + C C GF D CQ
Sbjct: 2551 CSCPQGFTQHSQWAQ-CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2609
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
DVDEC G G +S C N GG++C C GY R + +CV
Sbjct: 2610 DVDEC---AGRRGPCSYS---CANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 54.4 bits (125), Expect = 1e-06
Identities = 67/245 (27%), Positives = 88/245 (35%), Gaps = 41/245 (16%)
Query: 282 CVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSC- 333
CVC+ G CT VD E A L CD + PG C PG + C
Sbjct: 707 CVCNLGYEAGASGKDCTDVD-ECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICK 765
Query: 334 --DE-------NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN- 381
DE + C NL YTCKC G + D G C D + + C N
Sbjct: 766 DVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNL 825
Query: 382 ------TRCVNVVG---GYVCQ-------CLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
+ C +G G C+ C G+ R C +V+ECE C +
Sbjct: 826 QGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGR 884
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC-VNIDGGFRCECFTENCE 484
C NT GS+ C C +G D + VD E C V + G +R + C
Sbjct: 885 CVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCC--CS 942
Query: 485 LSCSW 489
+ W
Sbjct: 943 IGAVW 947
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 35/213 (16%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD-- 357
C R DP C V+ C N C+N + C+C +G D
Sbjct: 846 CERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDAS 905
Query: 358 GLTCQDV-----------DECQ--------------EAGGLHGHHCHSNTRCVNVVGGYV 392
G C DV DEC G + G C + ++ +
Sbjct: 906 GRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASL 965
Query: 393 CQCLGGYTRKDKFN----CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-- 446
C G+ +D + +V+EC+ C C NT GS+ C C G+ D
Sbjct: 966 CPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGTCRNTVGSFHCACAGGFALDAQER 1024
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC C CVN G F CECF
Sbjct: 1025 NCTDIDECRISPDLCGQGT-CVNTPGSFECECF 1056
Score = 49.2 bits (112), Expect = 5e-05
Identities = 63/225 (28%), Positives = 82/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGVDYCNM 329
G RF C G QC AC C P + G C GV +
Sbjct: 61 GSRFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSC-GV---SR 116
Query: 330 GHSCDENATCMNLNT--KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
G C + +CMN T +C C +G+ G + Q + C + G +G C RC V
Sbjct: 117 GSGC--SVSCMNGGTCRGASCLCQKGYTGT-VCGQPI--C-DRGCHNGGRCIGPNRCACV 170
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHAD-AVCTNTPG---SYTCR------- 436
G QC Y F V + C+ G A+C T G C
Sbjct: 171 YGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPH 230
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + +T C VDEC C + CVN+ G F C C
Sbjct: 231 PCRRGFIPNIHTGACQDVDECQAVPGLCQGGS-CVNMVGSFHCRC 274
Score = 49.2 bits (112), Expect = 5e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ C C GY +T C +DEC+ S C
Sbjct: 1563 DIDECQELPGLCQGGD-CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSIC-GPGT 1620
Query: 467 CVNIDGGFRCECFTENCELS 486
C N G + C C E +++
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVN 1640
Score = 48.4 bits (110), Expect = 8e-05
Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 23/226 (10%)
Query: 184 KLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEIT-CRPV-ECDRA 241
KL A + R E + C + +G+ + C+R + T C + ECDR
Sbjct: 1796 KLSPGGACVGRNECREIPNVCSHGDCMDTEGS-YMCLCHRGFQASADQTLCMDIDECDRQ 1854
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECV---CHDGNMQCTRVDPEL 298
C N CL C + +G+ EC V C G+ C
Sbjct: 1855 PCGNGTCKNIIGSYNCL--CFPGFVVTHNGDCVDFDECTTLVGQVCRFGH--CLNTAGSF 1910
Query: 299 ACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
C C + + G K C + C ++ +C TC NL + C C GFQ
Sbjct: 1911 HCL---CQDGFELTADG---KNCVDTNECLSLAGTCLPG-TCQNLEGSFRCICPPGFQVQ 1963
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C D+DEC E L C T C N G + C C G+ D
Sbjct: 1964 SDHCIDIDECSEEPNL----CLFGT-CTNSPGSFQCLCPPGFVLSD 2004
Score = 44.0 bits (99), Expect = 0.002
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ T C+D+DEC H C
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDEC----STHSSICGPG 1619
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N +G Y C C Y + NC+++
Sbjct: 1620 T-CYNTLGNYTCVCPAEYLQVNGGNNCMDM 1648
Score = 42.3 bits (95), Expect = 0.005
Identities = 24/56 (42%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 350 CNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
C +GF + T CQDVDECQ GL C + CVN+VG + C+C G+ D
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGL----CQGGS-CVNMVGSFHCRCPVGHRLSD 282
Score = 33.1 bits (72), Expect = 3.2
Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C +VDEC+ C + C N GS+ CRC G+
Sbjct: 245 CQDVDECQAVPGLCQGGS-CVNMVGSFHCRCPVGH 278
>X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein.
Length = 1246
Score = 131 bits (317), Expect = 7e-30
Identities = 69/163 (42%), Positives = 85/163 (52%), Gaps = 17/163 (10%)
Query: 327 CNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +G H CD NA C T++TC+C+ GF+GDG TC D+DEC E + C S+T C
Sbjct: 671 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSV----CGSHTIC 726
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVEV------DECEGNTHGCHAD--AVCTNTPG-SYTC 435
N G + C+C+ GY D+ CV V + CE H C A C T G SYTC
Sbjct: 727 NNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTC 786
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G+ GDG C VDEC CH A C N G F C+C
Sbjct: 787 SCLPGFSGDGQACQDVDECQPS--RCHPDAFCYNTPGSFTCQC 827
Score = 96.3 bits (229), Expect = 3e-19
Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAG----GLH 374
C +D C+ S C + C N + C+C +G+Q D TC V + + GLH
Sbjct: 707 CYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLH 766
Query: 375 GHHCHSNTRCVNVVGG-YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
+C+ G Y C CL G++ D C +VDEC+ + CH DA C NTPGS+
Sbjct: 767 NCDIPQRAQCIYTGGSSYTCSCLPGFSG-DGQACQDVDECQPSR--CHPDAFCYNTPGSF 823
Query: 434 TCRCRDGYEGDGYTCMHVD-ECTEGSHTCHH 463
TC+C+ GY+GDG+ C+ + E T H H
Sbjct: 824 TCQCKPGYQGDGFRCVPGEVEKTRCQHEREH 854
Score = 35.9 bits (79), Expect = 0.45
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM 449
+N C N H C A C + + C C GY G+G C+
Sbjct: 381 YNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCV 425
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGG 372
N H C +A C + T + C C G+ G+G C Q G
Sbjct: 391 NNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNG 435
Score = 31.9 bits (69), Expect = 7.3
Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C N GC +C TPGS TCRC D G
Sbjct: 1211 CSVNNGGC--THLCLATPGSRTCRCPDNTLG 1239
>M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein.
Length = 1247
Score = 131 bits (317), Expect = 7e-30
Identities = 69/163 (42%), Positives = 85/163 (52%), Gaps = 17/163 (10%)
Query: 327 CNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +G H CD NA C T++TC+C+ GF+GDG TC D+DEC E + C S+T C
Sbjct: 672 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSV----CGSHTIC 727
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVEV------DECEGNTHGCHAD--AVCTNTPG-SYTC 435
N G + C+C+ GY D+ CV V + CE H C A C T G SYTC
Sbjct: 728 NNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTC 787
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G+ GDG C VDEC CH A C N G F C+C
Sbjct: 788 SCLPGFSGDGQACQDVDECQPS--RCHPDAFCYNTPGSFTCQC 828
Score = 96.3 bits (229), Expect = 3e-19
Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAG----GLH 374
C +D C+ S C + C N + C+C +G+Q D TC V + + GLH
Sbjct: 708 CYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLH 767
Query: 375 GHHCHSNTRCVNVVGG-YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
+C+ G Y C CL G++ D C +VDEC+ + CH DA C NTPGS+
Sbjct: 768 NCDIPQRAQCIYTGGSSYTCSCLPGFSG-DGQACQDVDECQPSR--CHPDAFCYNTPGSF 824
Query: 434 TCRCRDGYEGDGYTCMHVD-ECTEGSHTCHH 463
TC+C+ GY+GDG+ C+ + E T H H
Sbjct: 825 TCQCKPGYQGDGFRCVPGEVEKTRCQHEREH 855
Score = 35.9 bits (79), Expect = 0.45
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM 449
+N C N H C A C + + C C GY G+G C+
Sbjct: 382 YNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCV 426
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGG 372
N H C +A C + T + C C G+ G+G C Q G
Sbjct: 392 NNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNG 436
Score = 31.9 bits (69), Expect = 7.3
Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C N GC +C TPGS TCRC D G
Sbjct: 1212 CSVNNGGC--THLCLATPGSRTCRCPDNTLG 1240
>M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein.
Length = 581
Score = 131 bits (317), Expect = 7e-30
Identities = 69/163 (42%), Positives = 85/163 (52%), Gaps = 17/163 (10%)
Query: 327 CNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +G H CD NA C T++TC+C+ GF+GDG TC D+DEC E + C S+T C
Sbjct: 6 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSV----CGSHTIC 61
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVEV------DECEGNTHGCHAD--AVCTNTPG-SYTC 435
N G + C+C+ GY D+ CV V + CE H C A C T G SYTC
Sbjct: 62 NNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTC 121
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G+ GDG C VDEC CH A C N G F C+C
Sbjct: 122 SCLPGFSGDGQACQDVDECQPS--RCHPDAFCYNTPGSFTCQC 162
Score = 96.3 bits (229), Expect = 3e-19
Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAG----GLH 374
C +D C+ S C + C N + C+C +G+Q D TC V + + GLH
Sbjct: 42 CYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLH 101
Query: 375 GHHCHSNTRCVNVVGG-YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
+C+ G Y C CL G++ D C +VDEC+ + CH DA C NTPGS+
Sbjct: 102 NCDIPQRAQCIYTGGSSYTCSCLPGFSG-DGQACQDVDECQPSR--CHPDAFCYNTPGSF 158
Query: 434 TCRCRDGYEGDGYTCMHVD-ECTEGSHTCHH 463
TC+C+ GY+GDG+ C+ + E T H H
Sbjct: 159 TCQCKPGYQGDGFRCVPGEVEKTRCQHEREH 189
Score = 31.9 bits (69), Expect = 7.3
Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C N GC +C TPGS TCRC D G
Sbjct: 546 CSVNNGGC--THLCLATPGSRTCRCPDNTLG 574
>AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 131 bits (317), Expect = 7e-30
Identities = 69/163 (42%), Positives = 85/163 (52%), Gaps = 17/163 (10%)
Query: 327 CNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +G H CD NA C T++TC+C+ GF+GDG TC D+DEC E + C S+T C
Sbjct: 672 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSV----CGSHTIC 727
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVEV------DECEGNTHGCHAD--AVCTNTPG-SYTC 435
N G + C+C+ GY D+ CV V + CE H C A C T G SYTC
Sbjct: 728 NNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTC 787
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G+ GDG C VDEC CH A C N G F C+C
Sbjct: 788 SCLPGFSGDGQACQDVDECQPS--RCHPDAFCYNTPGSFTCQC 828
Score = 96.3 bits (229), Expect = 3e-19
Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAG----GLH 374
C +D C+ S C + C N + C+C +G+Q D TC V + + GLH
Sbjct: 708 CYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLH 767
Query: 375 GHHCHSNTRCVNVVGG-YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
+C+ G Y C CL G++ D C +VDEC+ + CH DA C NTPGS+
Sbjct: 768 NCDIPQRAQCIYTGGSSYTCSCLPGFSG-DGQACQDVDECQPSR--CHPDAFCYNTPGSF 824
Query: 434 TCRCRDGYEGDGYTCMHVD-ECTEGSHTCHH 463
TC+C+ GY+GDG+ C+ + E T H H
Sbjct: 825 TCQCKPGYQGDGFRCVPGEVEKTRCQHEREH 855
Score = 35.9 bits (79), Expect = 0.45
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM 449
+N C N H C A C + + C C GY G+G C+
Sbjct: 382 YNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCV 426
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGG 372
N H C +A C + T + C C G+ G+G C Q G
Sbjct: 392 NNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNG 436
Score = 31.9 bits (69), Expect = 7.3
Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C N GC +C TPGS TCRC D G
Sbjct: 1212 CSVNNGGC--THLCLATPGSRTCRCPDNTLG 1240
>AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 131 bits (317), Expect = 7e-30
Identities = 69/163 (42%), Positives = 85/163 (52%), Gaps = 17/163 (10%)
Query: 327 CNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +G H CD NA C T++TC+C+ GF+GDG TC D+DEC E + C S+T C
Sbjct: 672 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSV----CGSHTIC 727
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVEV------DECEGNTHGCHAD--AVCTNTPG-SYTC 435
N G + C+C+ GY D+ CV V + CE H C A C T G SYTC
Sbjct: 728 NNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTC 787
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G+ GDG C VDEC CH A C N G F C+C
Sbjct: 788 SCLPGFSGDGQACQDVDECQPS--RCHPDAFCYNTPGSFTCQC 828
Score = 96.3 bits (229), Expect = 3e-19
Identities = 54/151 (35%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAG----GLH 374
C +D C+ S C + C N + C+C +G+Q D TC V + + GLH
Sbjct: 708 CYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLH 767
Query: 375 GHHCHSNTRCVNVVGG-YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
+C+ G Y C CL G++ D C +VDEC+ + CH DA C NTPGS+
Sbjct: 768 NCDIPQRAQCIYTGGSSYTCSCLPGFSG-DGQACQDVDECQPSR--CHPDAFCYNTPGSF 824
Query: 434 TCRCRDGYEGDGYTCMHVD-ECTEGSHTCHH 463
TC+C+ GY+GDG+ C+ + E T H H
Sbjct: 825 TCQCKPGYQGDGFRCVPGEVEKTRCQHEREH 855
Score = 35.9 bits (79), Expect = 0.45
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM 449
+N C N H C A C + + C C GY G+G C+
Sbjct: 382 YNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCV 426
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGG 372
N H C +A C + T + C C G+ G+G C Q G
Sbjct: 392 NNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNG 436
Score = 31.9 bits (69), Expect = 7.3
Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C N GC +C TPGS TCRC D G
Sbjct: 1212 CSVNNGGC--THLCLATPGSRTCRCPDNTLG 1240
>AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) variant
protein.
Length = 1241
Score = 131 bits (316), Expect = 9e-30
Identities = 69/163 (42%), Positives = 85/163 (52%), Gaps = 17/163 (10%)
Query: 327 CNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C +G H CD NA C T++TC+C+ GF+GDG TC D+DEC E + C S+T C
Sbjct: 671 CYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSV----CGSHTIC 726
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVEV------DECEGNTHGCHAD--AVCTNTPG-SYTC 435
N G + C+C+ GY D+ CV V + CE H C A C T G SYTC
Sbjct: 727 NNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTC 786
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G+ GDG C VDEC CH A C N G F C+C
Sbjct: 787 SCLPGFSGDGQACQDVDECHPS--RCHPDAFCYNTPGSFTCQC 827
Score = 95.5 bits (227), Expect = 5e-19
Identities = 54/151 (35%), Positives = 76/151 (50%), Gaps = 11/151 (7%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAG----GLH 374
C +D C+ S C + C N + C+C +G+Q D TC V + + GLH
Sbjct: 707 CYDIDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLH 766
Query: 375 GHHCHSNTRCVNVVGG-YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
+C+ G Y C CL G++ D C +VDEC + CH DA C NTPGS+
Sbjct: 767 NCDIPQRAQCIYTGGSSYTCSCLPGFSG-DGQACQDVDECHPSR--CHPDAFCYNTPGSF 823
Query: 434 TCRCRDGYEGDGYTCMHVD-ECTEGSHTCHH 463
TC+C+ GY+GDG+ C+ + E T H H
Sbjct: 824 TCQCKPGYQGDGFRCVPGEVEKTRCQHEREH 854
Score = 35.9 bits (79), Expect = 0.45
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM 449
+N C N H C A C + + C C GY G+G C+
Sbjct: 381 YNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCV 425
Score = 33.9 bits (74), Expect = 1.8
Identities = 14/45 (31%), Positives = 19/45 (42%)
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGG 372
N H C +A C + T + C C G+ G+G C Q G
Sbjct: 391 NNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNG 435
Score = 31.9 bits (69), Expect = 7.3
Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C N GC +C TPGS TCRC D G
Sbjct: 1206 CSVNNGGC--THLCLATPGSRTCRCPDNTLG 1234
>D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 126 bits (303), Expect = 3e-28
Identities = 66/165 (40%), Positives = 86/165 (52%), Gaps = 16/165 (9%)
Query: 324 VDYCNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN 381
V+ C G H CD A C YTC+C G+QGDG C D +EC A G H C N
Sbjct: 761 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENEC--ATGFH--RCGPN 816
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEV----DECEGNTHGCH--ADAVCTNTPGS-Y 433
+ C+N+ G Y C+C GY D+ C+ + + CE +H C A C + GS +
Sbjct: 817 SVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTF 876
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C C GY GDG+ C VDEC+E + CH +A C N G F C C
Sbjct: 877 SCACLPGYAGDGHQCTDVDECSE--NRCHPAATCYNTPGSFSCRC 919
Score = 100 bits (240), Expect = 1e-20
Identities = 64/194 (32%), Positives = 87/194 (44%), Gaps = 22/194 (11%)
Query: 284 CHDGNMQC---TRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATC 339
C+DG+ C R P C+ + G + C + C G H C N+ C
Sbjct: 764 CYDGSHMCDTTARCHPGTGVD-YTCECASGYQGDG---RNCVDENECATGFHRCGPNSVC 819
Query: 340 MNLNTKYTCKCNQGFQ--GDGLTC----QDVDECQEAGGLHGHHCHSNTRCVNVVGG-YV 392
+NL Y C+C G++ D TC + C++ G H RCV+ G +
Sbjct: 820 INLPGSYRCECRSGYEFADDRHTCILITPPANPCED--GSHTCAPAGQARCVHHGGSTFS 877
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C CL GY D C +VDEC N CH A C NTPGS++CRC+ GY GDG+ C +
Sbjct: 878 CACLPGYAG-DGHQCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGYYGDGFQC--IP 932
Query: 453 ECTEGSHTCHHSAR 466
+ T C R
Sbjct: 933 DSTSSLTPCEQQQR 946
Score = 74.1 bits (174), Expect = 1e-12
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 402 KDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGDGYTCMHVDECTEGSHT 460
K+ + V+ C +H C A C G YTC C GY+GDG C+ +EC G H
Sbjct: 753 KEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHR 812
Query: 461 CHHSARCVNIDGGFRCEC 478
C ++ C+N+ G +RCEC
Sbjct: 813 CGPNSVCINLPGSYRCEC 830
Score = 38.7 bits (86), Expect = 0.064
Identities = 15/54 (27%), Positives = 24/54 (44%)
Query: 396 LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM 449
+G T +N + CE N C A CT+ + C C+ + G+G C+
Sbjct: 472 IGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCL 525
Score = 31.9 bits (69), Expect = 7.3
Identities = 15/54 (27%), Positives = 19/54 (35%), Gaps = 1/54 (1%)
Query: 327 CNMGH-SCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C H C +A C + T + C C F G+G C G H H
Sbjct: 489 CEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHLH 542
>AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein.
Length = 1375
Score = 126 bits (303), Expect = 3e-28
Identities = 66/165 (40%), Positives = 86/165 (52%), Gaps = 16/165 (9%)
Query: 324 VDYCNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN 381
V+ C G H CD A C YTC+C G+QGDG C D +EC A G H C N
Sbjct: 760 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENEC--ATGFH--RCGPN 815
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEV----DECEGNTHGCH--ADAVCTNTPGS-Y 433
+ C+N+ G Y C+C GY D+ C+ + + CE +H C A C + GS +
Sbjct: 816 SVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTF 875
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C C GY GDG+ C VDEC+E + CH +A C N G F C C
Sbjct: 876 SCACLPGYAGDGHQCTDVDECSE--NRCHPAATCYNTPGSFSCRC 918
Score = 100 bits (240), Expect = 1e-20
Identities = 64/194 (32%), Positives = 87/194 (44%), Gaps = 22/194 (11%)
Query: 284 CHDGNMQC---TRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATC 339
C+DG+ C R P C+ + G + C + C G H C N+ C
Sbjct: 763 CYDGSHMCDTTARCHPGTGVD-YTCECASGYQGDG---RNCVDENECATGFHRCGPNSVC 818
Query: 340 MNLNTKYTCKCNQGFQ--GDGLTC----QDVDECQEAGGLHGHHCHSNTRCVNVVGG-YV 392
+NL Y C+C G++ D TC + C++ G H RCV+ G +
Sbjct: 819 INLPGSYRCECRSGYEFADDRHTCILITPPANPCED--GSHTCAPAGQARCVHHGGSTFS 876
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C CL GY D C +VDEC N CH A C NTPGS++CRC+ GY GDG+ C +
Sbjct: 877 CACLPGYAG-DGHQCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGYYGDGFQC--IP 931
Query: 453 ECTEGSHTCHHSAR 466
+ T C R
Sbjct: 932 DSTSSLTPCEQQQR 945
Score = 74.1 bits (174), Expect = 1e-12
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 402 KDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGDGYTCMHVDECTEGSHT 460
K+ + V+ C +H C A C G YTC C GY+GDG C+ +EC G H
Sbjct: 752 KEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHR 811
Query: 461 CHHSARCVNIDGGFRCEC 478
C ++ C+N+ G +RCEC
Sbjct: 812 CGPNSVCINLPGSYRCEC 829
Score = 38.7 bits (86), Expect = 0.064
Identities = 15/54 (27%), Positives = 24/54 (44%)
Query: 396 LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM 449
+G T +N + CE N C A CT+ + C C+ + G+G C+
Sbjct: 471 IGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCL 524
Score = 31.9 bits (69), Expect = 7.3
Identities = 15/54 (27%), Positives = 19/54 (35%), Gaps = 1/54 (1%)
Query: 327 CNMGH-SCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C H C +A C + T + C C F G+G C G H H
Sbjct: 488 CEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHLH 541
>AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 126 bits (303), Expect = 3e-28
Identities = 66/165 (40%), Positives = 86/165 (52%), Gaps = 16/165 (9%)
Query: 324 VDYCNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN 381
V+ C G H CD A C YTC+C G+QGDG C D +EC A G H C N
Sbjct: 761 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENEC--ATGFH--RCGPN 816
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEV----DECEGNTHGCH--ADAVCTNTPGS-Y 433
+ C+N+ G Y C+C GY D+ C+ + + CE +H C A C + GS +
Sbjct: 817 SVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTF 876
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C C GY GDG+ C VDEC+E + CH +A C N G F C C
Sbjct: 877 SCACLPGYAGDGHQCTDVDECSE--NRCHPAATCYNTPGSFSCRC 919
Score = 100 bits (240), Expect = 1e-20
Identities = 64/194 (32%), Positives = 87/194 (44%), Gaps = 22/194 (11%)
Query: 284 CHDGNMQC---TRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATC 339
C+DG+ C R P C+ + G + C + C G H C N+ C
Sbjct: 764 CYDGSHMCDTTARCHPGTGVD-YTCECASGYQGDG---RNCVDENECATGFHRCGPNSVC 819
Query: 340 MNLNTKYTCKCNQGFQ--GDGLTC----QDVDECQEAGGLHGHHCHSNTRCVNVVGG-YV 392
+NL Y C+C G++ D TC + C++ G H RCV+ G +
Sbjct: 820 INLPGSYRCECRSGYEFADDRHTCILITPPANPCED--GSHTCAPAGQARCVHHGGSTFS 877
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C CL GY D C +VDEC N CH A C NTPGS++CRC+ GY GDG+ C +
Sbjct: 878 CACLPGYAG-DGHQCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGYYGDGFQC--IP 932
Query: 453 ECTEGSHTCHHSAR 466
+ T C R
Sbjct: 933 DSTSSLTPCEQQQR 946
Score = 74.1 bits (174), Expect = 1e-12
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 402 KDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGDGYTCMHVDECTEGSHT 460
K+ + V+ C +H C A C G YTC C GY+GDG C+ +EC G H
Sbjct: 753 KEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHR 812
Query: 461 CHHSARCVNIDGGFRCEC 478
C ++ C+N+ G +RCEC
Sbjct: 813 CGPNSVCINLPGSYRCEC 830
Score = 38.7 bits (86), Expect = 0.064
Identities = 15/54 (27%), Positives = 24/54 (44%)
Query: 396 LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM 449
+G T +N + CE N C A CT+ + C C+ + G+G C+
Sbjct: 472 IGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCL 525
Score = 31.9 bits (69), Expect = 7.3
Identities = 15/54 (27%), Positives = 19/54 (35%), Gaps = 1/54 (1%)
Query: 327 CNMGH-SCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C H C +A C + T + C C F G+G C G H H
Sbjct: 489 CEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHLH 542
>M17778-1|AAA36799.1| 640|Homo sapiens protein ( Human uromodulin
(Tamm-Horsfall glycoprotein) mRNA, complete cds. ).
Length = 640
Score = 124 bits (300), Expect = 8e-28
Identities = 61/137 (44%), Positives = 71/137 (51%), Gaps = 10/137 (7%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C NATC TC C +GF GDGLTC D+DEC G H+C +N+ CVN G +
Sbjct: 35 CHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPG---AHNCSANSSCVNTPGSFS 91
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV 451
C C G+ C +VDEC E CHA A C N GSY C C GY GDG+ C
Sbjct: 92 CVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC--- 148
Query: 452 DECTEGSHTCHHSARCV 468
EC+ GS C CV
Sbjct: 149 -ECSPGS--CGPGLDCV 162
Score = 94.7 bits (225), Expect = 9e-19
Identities = 44/104 (42%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CHSN C C C G+T D CV++DEC H C A++ C NTPGS++C
Sbjct: 35 CHSNATCTEDEAVTTCTCQEGFTG-DGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCV 93
Query: 437 CRDGYE-GDGYTCMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
C +G+ G C VDEC E G CH A CVN+ G + C C
Sbjct: 94 CPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
Score = 83.4 bits (197), Expect = 2e-15
Identities = 44/108 (40%), Positives = 59/108 (54%), Gaps = 11/108 (10%)
Query: 321 CPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHH 377
C +D C + H+C N++C+N ++C C +GF+ GL C DVDEC E G H
Sbjct: 63 CVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPG---LSH 119
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
CH+ CVNVVG Y+C C GY R D ++C EC + G D V
Sbjct: 120 CHALATCVNVVGSYLCVCPAGY-RGDGWHC----ECSPGSCGPGLDCV 162
>M15881-1|AAA36798.1| 640|Homo sapiens protein ( Human uromodulin
(Tamm-Horsfall glycoprotein) mRNA, complete cds. ).
Length = 640
Score = 124 bits (300), Expect = 8e-28
Identities = 61/137 (44%), Positives = 71/137 (51%), Gaps = 10/137 (7%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C NATC TC C +GF GDGLTC D+DEC G H+C +N+ CVN G +
Sbjct: 35 CHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPG---AHNCSANSSCVNTPGSFS 91
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV 451
C C G+ C +VDEC E CHA A C N GSY C C GY GDG+ C
Sbjct: 92 CVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC--- 148
Query: 452 DECTEGSHTCHHSARCV 468
EC+ GS C CV
Sbjct: 149 -ECSPGS--CGPGLDCV 162
Score = 94.7 bits (225), Expect = 9e-19
Identities = 44/104 (42%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CHSN C C C G+T D CV++DEC H C A++ C NTPGS++C
Sbjct: 35 CHSNATCTEDEAVTTCTCQEGFTG-DGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCV 93
Query: 437 CRDGYE-GDGYTCMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
C +G+ G C VDEC E G CH A CVN+ G + C C
Sbjct: 94 CPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
Score = 83.4 bits (197), Expect = 2e-15
Identities = 44/108 (40%), Positives = 59/108 (54%), Gaps = 11/108 (10%)
Query: 321 CPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHH 377
C +D C + H+C N++C+N ++C C +GF+ GL C DVDEC E G H
Sbjct: 63 CVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPG---LSH 119
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
CH+ CVNVVG Y+C C GY R D ++C EC + G D V
Sbjct: 120 CHALATCVNVVGSYLCVCPAGY-RGDGWHC----ECSPGSCGPGLDCV 162
>BC035975-1|AAH35975.1| 611|Homo sapiens UMOD protein protein.
Length = 611
Score = 124 bits (300), Expect = 8e-28
Identities = 61/137 (44%), Positives = 71/137 (51%), Gaps = 10/137 (7%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C NATC TC C +GF GDGLTC D+DEC G H+C +N+ CVN G +
Sbjct: 35 CHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPG---AHNCSANSSCVNTPGSFS 91
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV 451
C C G+ C +VDEC E CHA A C N GSY C C GY GDG+ C
Sbjct: 92 CVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC--- 148
Query: 452 DECTEGSHTCHHSARCV 468
EC+ GS C CV
Sbjct: 149 -ECSPGS--CGPGLDCV 162
Score = 94.7 bits (225), Expect = 9e-19
Identities = 44/104 (42%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CHSN C C C G+T D CV++DEC H C A++ C NTPGS++C
Sbjct: 35 CHSNATCTEDEAVTTCTCQEGFTG-DGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCV 93
Query: 437 CRDGYE-GDGYTCMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
C +G+ G C VDEC E G CH A CVN+ G + C C
Sbjct: 94 CPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
Score = 83.4 bits (197), Expect = 2e-15
Identities = 44/108 (40%), Positives = 59/108 (54%), Gaps = 11/108 (10%)
Query: 321 CPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHH 377
C +D C + H+C N++C+N ++C C +GF+ GL C DVDEC E G H
Sbjct: 63 CVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPG---LSH 119
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
CH+ CVNVVG Y+C C GY R D ++C EC + G D V
Sbjct: 120 CHALATCVNVVGSYLCVCPAGY-RGDGWHC----ECSPGSCGPGLDCV 162
>AY162970-1|AAO64446.1| 640|Homo sapiens uromodulin precursor
protein.
Length = 640
Score = 124 bits (300), Expect = 8e-28
Identities = 61/137 (44%), Positives = 71/137 (51%), Gaps = 10/137 (7%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C NATC TC C +GF GDGLTC D+DEC G H+C +N+ CVN G +
Sbjct: 35 CHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPG---AHNCSANSSCVNTPGSFS 91
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV 451
C C G+ C +VDEC E CHA A C N GSY C C GY GDG+ C
Sbjct: 92 CVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC--- 148
Query: 452 DECTEGSHTCHHSARCV 468
EC+ GS C CV
Sbjct: 149 -ECSPGS--CGPGLDCV 162
Score = 94.7 bits (225), Expect = 9e-19
Identities = 44/104 (42%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CHSN C C C G+T D CV++DEC H C A++ C NTPGS++C
Sbjct: 35 CHSNATCTEDEAVTTCTCQEGFTG-DGLTCVDLDECAIPGAHNCSANSSCVNTPGSFSCV 93
Query: 437 CRDGYE-GDGYTCMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
C +G+ G C VDEC E G CH A CVN+ G + C C
Sbjct: 94 CPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVC 137
Score = 83.4 bits (197), Expect = 2e-15
Identities = 44/108 (40%), Positives = 59/108 (54%), Gaps = 11/108 (10%)
Query: 321 CPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHH 377
C +D C + H+C N++C+N ++C C +GF+ GL C DVDEC E G H
Sbjct: 63 CVDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPG---LSH 119
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAV 425
CH+ CVNVVG Y+C C GY R D ++C EC + G D V
Sbjct: 120 CHALATCVNVVGSYLCVCPAGY-RGDGWHC----ECSPGSCGPGLDCV 162
>BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein.
Length = 969
Score = 123 bits (297), Expect = 2e-27
Identities = 65/165 (39%), Positives = 85/165 (51%), Gaps = 16/165 (9%)
Query: 324 VDYCNMG-HSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN 381
V+ C G H CD A C YTC+C G+QGDG C D +EC A G H C N
Sbjct: 354 VNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENEC--ATGFH--RCGPN 409
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEV----DECEGNTHGCH--ADAVCTNTPGS-Y 433
+ C+N+ G Y C+C Y D+ C+ + + CE +H C A C + GS +
Sbjct: 410 SVCINLPGSYRCECRSAYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTF 469
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C C GY GDG+ C VDEC+E + CH +A C N G F C C
Sbjct: 470 SCACLPGYAGDGHQCTDVDECSE--NRCHPAATCYNTPGSFSCRC 512
Score = 98.3 bits (234), Expect = 7e-20
Identities = 63/194 (32%), Positives = 86/194 (44%), Gaps = 22/194 (11%)
Query: 284 CHDGNMQC---TRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATC 339
C+DG+ C R P C+ + G + C + C G H C N+ C
Sbjct: 357 CYDGSHMCDTTARCHPGTGVD-YTCECASGYQGDG---RNCVDENECATGFHRCGPNSVC 412
Query: 340 MNLNTKYTCKCNQGFQ--GDGLTC----QDVDECQEAGGLHGHHCHSNTRCVNVVGG-YV 392
+NL Y C+C ++ D TC + C++ G H RCV+ G +
Sbjct: 413 INLPGSYRCECRSAYEFADDRHTCILITPPANPCED--GSHTCAPAGQARCVHHGGSTFS 470
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C CL GY D C +VDEC N CH A C NTPGS++CRC+ GY GDG+ C +
Sbjct: 471 CACLPGYAG-DGHQCTDVDECSENR--CHPAATCYNTPGSFSCRCQPGYYGDGFQC--IP 525
Query: 453 ECTEGSHTCHHSAR 466
+ T C R
Sbjct: 526 DSTSSLTPCEQQQR 539
Score = 74.1 bits (174), Expect = 1e-12
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 1/78 (1%)
Query: 402 KDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGDGYTCMHVDECTEGSHT 460
K+ + V+ C +H C A C G YTC C GY+GDG C+ +EC G H
Sbjct: 346 KEDSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHR 405
Query: 461 CHHSARCVNIDGGFRCEC 478
C ++ C+N+ G +RCEC
Sbjct: 406 CGPNSVCINLPGSYRCEC 423
>AK222891-1|BAD96611.1| 810|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like sequence 2
isofor protein.
Length = 810
Score = 119 bits (287), Expect = 3e-26
Identities = 65/167 (38%), Positives = 81/167 (48%), Gaps = 24/167 (14%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 78 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 133
Query: 382 TRCVNVVGGYVCQCLGGYTRK--DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ K D C +V+EC + CH+ C N GSY CRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 440 GYE-------GDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G++ G T C VDEC+ G H C S C N G + C C
Sbjct: 194 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240
Score = 101 bits (242), Expect = 8e-21
Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C ++++C+N C+CN GF TC D++EC + C + C
Sbjct: 33 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVS---CGKFSDCW 86
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 147 CLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 191
Score = 99.5 bits (237), Expect = 3e-20
Identities = 51/133 (38%), Positives = 66/133 (49%), Gaps = 15/133 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ---GDGLTCQDVDECQEAGGLHGH 376
C VD C C TC+N YTC+C GF+ D C DV+EC +
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQ----N 172
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-------TRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
CHS+T C+N VG Y C+C G+ + C +VDEC H C + VC NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 430 PGSYTCRCRDGYE 442
GSY+CRCR G++
Sbjct: 233 VGSYSCRCRPGWK 245
>AF114491-1|AAF21974.1| 823|Homo sapiens EGF-like module EMR2
protein.
Length = 823
Score = 119 bits (287), Expect = 3e-26
Identities = 65/167 (38%), Positives = 81/167 (48%), Gaps = 24/167 (14%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 78 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 133
Query: 382 TRCVNVVGGYVCQCLGGYTRK--DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ K D C +V+EC + CH+ C N GSY CRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 440 GYE-------GDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G++ G T C VDEC+ G H C S C N G + C C
Sbjct: 194 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240
Score = 101 bits (242), Expect = 8e-21
Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C ++++C+N C+CN GF TC D++EC + C + C
Sbjct: 33 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVS---CGKFSDCW 86
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 147 CLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 191
Score = 99.5 bits (237), Expect = 3e-20
Identities = 51/133 (38%), Positives = 66/133 (49%), Gaps = 15/133 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ---GDGLTCQDVDECQEAGGLHGH 376
C VD C C TC+N YTC+C GF+ D C DV+EC +
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQ----N 172
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-------TRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
CHS+T C+N VG Y C+C G+ + C +VDEC H C + VC NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 430 PGSYTCRCRDGYE 442
GSY+CRCR G++
Sbjct: 233 VGSYSCRCRPGWK 245
>AB065931-1|BAC06146.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 119 bits (287), Expect = 3e-26
Identities = 65/167 (38%), Positives = 81/167 (48%), Gaps = 24/167 (14%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 79 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 134
Query: 382 TRCVNVVGGYVCQCLGGYTRK--DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ K D C +V+EC + CH+ C N GSY CRCR
Sbjct: 135 GTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 194
Query: 440 GYE-------GDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G++ G T C VDEC+ G H C S C N G + C C
Sbjct: 195 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 241
Score = 101 bits (242), Expect = 8e-21
Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C ++++C+N C+CN GF TC D++EC + C + C
Sbjct: 34 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVS---CGKFSDCW 87
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 88 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 147
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 148 CLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 192
Score = 99.5 bits (237), Expect = 3e-20
Identities = 51/133 (38%), Positives = 66/133 (49%), Gaps = 15/133 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ---GDGLTCQDVDECQEAGGLHGH 376
C VD C C TC+N YTC+C GF+ D C DV+EC +
Sbjct: 118 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQ----N 173
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-------TRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
CHS+T C+N VG Y C+C G+ + C +VDEC H C + VC NT
Sbjct: 174 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 233
Query: 430 PGSYTCRCRDGYE 442
GSY+CRCR G++
Sbjct: 234 VGSYSCRCRPGWK 246
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 119 bits (286), Expect = 4e-26
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 5190 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 5241
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 5242 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 5301
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM ++EC + C H +C N G F+C C
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVPKPCAH--QCSNTPGSFKCIC 5341
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 5104 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 5157
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 5158 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 5214
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 5215 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 5254
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 5143
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 5202
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 5203 HQ--RCFNAIGSFHCGC 5217
Score = 74.9 bits (176), Expect = 8e-13
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 5131 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 5178
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 5179 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 5227
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 5228 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 5282
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C++++ECE C C+NTPGS+ C
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCI 5340
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 5341 CPPGQHLLGDGKSC 5354
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 5430 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 5486
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 5487 RMCFNMRGSYQC 5498
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 5470
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 5471 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5527
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 5430 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 5483
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 5484 GPNRMCFNMRGSYQC 5498
>AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 119 bits (286), Expect = 4e-26
Identities = 99/337 (29%), Positives = 132/337 (39%), Gaps = 37/337 (10%)
Query: 160 TCGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCD----CQKS-----CYSNGTV 210
T G F + TV +I + K VG ++ L C C + CY T
Sbjct: 739 TLGSFYCVNHTVLCADGYILNAHRKCVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTC 798
Query: 211 HADGATWQRDCNRCS-CVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYE 269
A +C C G TC+P C+N G ++C+
Sbjct: 799 EPGYALKDGECEDVDECAMGTHTCQPGFL----CQNT---KGSFYCQARQRCMDGFLQDP 851
Query: 270 HGERFAPKECAECV--CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYC 327
G EC C G C C R P + + + K C V+ C
Sbjct: 852 EGNCVDINECTSLSEPCRPG-FSCINTVGSYTCQRNPLICARGYHASDDGAK-CVDVNEC 909
Query: 328 NMG-HSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRC 384
G H C E C NL Y C C GFQ D G C DV+EC + G H C
Sbjct: 910 ETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT-----C 964
Query: 385 VNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE- 442
N +G Y C C G+ D C +V+ECE C + C N GSY C CR GY+
Sbjct: 965 ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQR--CSQE--CANIYGSYQCYCRQGYQL 1020
Query: 443 -GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
DG+TC +DEC +G+ + RC+N+ G ++C C
Sbjct: 1021 AEDGHTCTDIDECAQGAGILC-TFRCLNVPGSYQCAC 1056
Score = 107 bits (258), Expect = 9e-23
Identities = 61/164 (37%), Positives = 76/164 (46%), Gaps = 19/164 (11%)
Query: 321 CPGVDYC--NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
C V+ C + G C TC N Y C C GF DG C+DV+EC+
Sbjct: 946 CIDVNECWASPGRLCQH--TCENTLGSYRCSCASGFLLAADGKRCEDVNECE------AQ 997
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C + C N+ G Y C C GY +D C ++DEC G C N PGSY C
Sbjct: 998 RC--SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGA-GILCTFRCLNVPGSYQC 1054
Query: 436 RCRD-GYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C + GY +G +C VDEC G+H C + C NI G FRC
Sbjct: 1055 ACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
Score = 93.9 bits (223), Expect = 2e-18
Identities = 53/167 (31%), Positives = 68/167 (40%), Gaps = 17/167 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCH 379
P + C C + C + C C G+ DG++C+D DEC + H C
Sbjct: 678 PQPNTCKDNGPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDQDECL----MGAHDCS 731
Query: 380 SNTRCVNVVGGYVCQ-----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CVN +G + C C GY CV +EC + H C C NT GS+
Sbjct: 732 RRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVGKNECVTDLHTCSRGEHCVNTLGSFH 791
Query: 435 C----RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCE 477
C C GY C VDEC G+HTC C N G F C+
Sbjct: 792 CYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 838
Score = 58.8 bits (136), Expect = 6e-08
Identities = 67/267 (25%), Positives = 102/267 (38%), Gaps = 36/267 (13%)
Query: 177 HIHDLSLKLVGAEARISRLEQCDCQKSCYS-NGTVHAD-GATWQRDCNRCSCVH-GEITC 233
H D K V + + +C + C++ G+ D A +QRD C+ E
Sbjct: 895 HASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 954
Query: 234 RPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTR 293
P + C+N + G +C LL + G+R ++ EC + +C
Sbjct: 955 SPGRLCQHTCENTL---GSYRCSCASGFLLAAD----GKRC--EDVNECEAQRCSQECAN 1005
Query: 294 VDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKC-NQ 352
+ C C Q + G C +D C G C+N+ Y C C Q
Sbjct: 1006 IYGSYQCY---CRQGYQLAEDGHTCT---DIDECAQGAGILCTFRCLNVPGSYQCACPEQ 1059
Query: 353 GFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC---QCLGGYTRKDKFNC 407
G+ +G +C+DVDEC L H+C C N+ G + C +C Y + K
Sbjct: 1060 GYTMTANGRSCKDVDEC----ALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK--- 1112
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYT 434
+CE T CH C N+P T
Sbjct: 1113 ---TKCERTT--CHDFLECQNSPARIT 1134
Score = 51.2 bits (117), Expect = 1e-05
Identities = 25/61 (40%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTEN 482
VC+ GS C C GY DG +C DEC G+H C CVN G F C T
Sbjct: 692 VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVL 751
Query: 483 C 483
C
Sbjct: 752 C 752
Score = 35.5 bits (78), Expect = 0.60
Identities = 40/151 (26%), Positives = 54/151 (35%), Gaps = 22/151 (14%)
Query: 233 CRPVECDRAE-CKNPVLHPGECCPTCLRQ-----------CL----LWGNLYEHGERFAP 276
C VEC E C L PG CC TC++Q CL + G + F
Sbjct: 33 CTGVECPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCLQGGFVRGRVPAGQSYFVD 92
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
EC C G + + + CP LP + + V + C C V + GH
Sbjct: 93 FGSTECSCPPGGGKIS--CQFMLCPELPPNCIEAV-VVADSCPQCGQVGCVHAGHEYAAG 149
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDEC 367
T ++L C C G L C + C
Sbjct: 150 HT-VHLPPCRACHCPDA--GGELICYQLPGC 177
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 119 bits (286), Expect = 4e-26
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 5190 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 5241
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 5242 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 5301
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM ++EC + C H +C N G F+C C
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVPKPCAH--QCSNTPGSFKCIC 5341
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 5104 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 5157
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 5158 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 5214
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 5215 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 5254
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 5143
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 5202
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 5203 HQ--RCFNAIGSFHCGC 5217
Score = 74.9 bits (176), Expect = 8e-13
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 5131 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 5178
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 5179 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 5227
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 5228 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 5282
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C++++ECE C C+NTPGS+ C
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCI 5340
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 5341 CPPGQHLLGDGKSC 5354
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 5430 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 5486
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 5487 RMCFNMRGSYQC 5498
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 5470
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 5471 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5527
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 5430 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 5483
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 5484 GPNRMCFNMRGSYQC 5498
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 119 bits (286), Expect = 4e-26
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 5190 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 5241
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 5242 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 5301
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM ++EC + C H +C N G F+C C
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVPKPCAH--QCSNTPGSFKCIC 5341
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 5104 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 5157
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 5158 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 5214
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 5215 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 5254
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 5143
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 5202
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 5203 HQ--RCFNAIGSFHCGC 5217
Score = 74.9 bits (176), Expect = 8e-13
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 5131 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 5178
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 5179 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 5227
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 5228 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 5282
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C++++ECE C C+NTPGS+ C
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCI 5340
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 5341 CPPGQHLLGDGKSC 5354
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 5430 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 5486
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 5487 RMCFNMRGSYQC 5498
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 5470
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 5471 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5527
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 5430 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 5483
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 5484 GPNRMCFNMRGSYQC 5498
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 119 bits (286), Expect = 4e-26
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 5190 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 5241
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 5242 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 5301
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM ++EC + C H +C N G F+C C
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVPKPCAH--QCSNTPGSFKCIC 5341
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 5104 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 5157
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 5158 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 5214
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 5215 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 5254
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 5143
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 5202
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 5203 HQ--RCFNAIGSFHCGC 5217
Score = 74.9 bits (176), Expect = 8e-13
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 5131 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 5178
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 5179 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 5227
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 5228 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 5282
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C++++ECE C C+NTPGS+ C
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCI 5340
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 5341 CPPGQHLLGDGKSC 5354
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 5430 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 5486
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 5487 RMCFNMRGSYQC 5498
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 5470
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 5471 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5527
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 5430 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 5483
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 5484 GPNRMCFNMRGSYQC 5498
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 119 bits (286), Expect = 4e-26
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 5190 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 5241
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 5242 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 5301
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM ++EC + C H +C N G F+C C
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVPKPCAH--QCSNTPGSFKCIC 5341
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 5104 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 5157
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 5158 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 5214
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 5215 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 5254
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 5143
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 5202
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 5203 HQ--RCFNAIGSFHCGC 5217
Score = 74.9 bits (176), Expect = 8e-13
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 5131 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 5178
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 5179 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 5227
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 5228 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 5282
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C++++ECE C C+NTPGS+ C
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCI 5340
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 5341 CPPGQHLLGDGKSC 5354
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 5430 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 5486
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 5487 RMCFNMRGSYQC 5498
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 5470
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 5471 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5527
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 5430 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 5483
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 5484 GPNRMCFNMRGSYQC 5498
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 119 bits (286), Expect = 4e-26
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 5190 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 5241
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 5242 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 5301
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM ++EC + C H +C N G F+C C
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVPKPCAH--QCSNTPGSFKCIC 5341
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 5104 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 5157
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 5158 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 5214
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 5215 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 5254
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 5143
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 5202
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 5203 HQ--RCFNAIGSFHCGC 5217
Score = 74.9 bits (176), Expect = 8e-13
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 5131 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 5178
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 5179 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 5227
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 5228 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 5282
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C++++ECE C C+NTPGS+ C
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCI 5340
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 5341 CPPGQHLLGDGKSC 5354
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 5430 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 5486
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 5487 RMCFNMRGSYQC 5498
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 5470
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 5471 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5527
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 5430 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 5483
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 5484 GPNRMCFNMRGSYQC 5498
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 119 bits (286), Expect = 4e-26
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 5190 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 5241
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 5242 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 5301
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM ++EC + C H +C N G F+C C
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVPKPCAH--QCSNTPGSFKCIC 5341
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 5104 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 5157
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 5158 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 5214
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 5215 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 5254
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 5143
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 5202
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 5203 HQ--RCFNAIGSFHCGC 5217
Score = 74.9 bits (176), Expect = 8e-13
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 5131 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 5178
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 5179 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 5227
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 5228 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 5282
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C++++ECE C C+NTPGS+ C
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCI 5340
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 5341 CPPGQHLLGDGKSC 5354
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 5430 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 5486
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 5487 RMCFNMRGSYQC 5498
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 5470
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 5471 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5527
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 5430 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 5483
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 5484 GPNRMCFNMRGSYQC 5498
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 119 bits (286), Expect = 4e-26
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 5190 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 5241
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 5242 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 5301
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM ++EC + C H +C N G F+C C
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVPKPCAH--QCSNTPGSFKCIC 5341
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 5104 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 5157
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 5158 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 5214
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 5215 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 5254
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 5091 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 5143
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 5144 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 5202
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 5203 HQ--RCFNAIGSFHCGC 5217
Score = 74.9 bits (176), Expect = 8e-13
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 5131 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 5178
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 5179 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 5227
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 5228 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 5282
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C++++ECE C C+NTPGS+ C
Sbjct: 5283 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCI 5340
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 5341 CPPGQHLLGDGKSC 5354
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 5430 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 5486
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 5487 RMCFNMRGSYQC 5498
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 5470
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 5471 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5527
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 5430 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 5483
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 5484 GPNRMCFNMRGSYQC 5498
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 119 bits (286), Expect = 4e-26
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 2228 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 2279
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 2280 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 2339
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM ++EC + C H +C N G F+C C
Sbjct: 2340 RGYRSQGVGRPCMDINECEQVPKPCAH--QCSNTPGSFKCIC 2379
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 2142 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 2195
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 2196 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 2252
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 2253 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 2292
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 2129 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 2181
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 2182 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 2240
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 2241 HQ--RCFNAIGSFHCGC 2255
Score = 74.9 bits (176), Expect = 8e-13
Identities = 74/254 (29%), Positives = 101/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 2169 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 2216
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 2217 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 2265
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 2266 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 2320
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C++++ECE C C+NTPGS+ C
Sbjct: 2321 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQ--CSNTPGSFKCI 2378
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 2379 CPPGQHLLGDGKSC 2392
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 2468 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 2524
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 2525 RMCFNMRGSYQC 2536
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 2457 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 2508
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 2509 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 2565
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 2468 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 2521
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 2522 GPNRMCFNMRGSYQC 2536
>U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor
protein.
Length = 956
Score = 118 bits (285), Expect = 5e-26
Identities = 60/165 (36%), Positives = 78/165 (47%), Gaps = 17/165 (10%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
K C + H+C C+N+ Y C+C QG+ D TC+ D C + H
Sbjct: 235 KLCTAHMCSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLC----AMEDH 288
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+C CVNV G +VCQC GY +D CV VD C HGC + C N GSY C
Sbjct: 289 NCEQ--LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHE--CVNADGSYLC 344
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +G+ D TC +D C +H C H CVN D + C C
Sbjct: 345 QCHEGFALNPDKKTCTKIDYCASSNHGCQH--ECVNTDDSYSCHC 387
Score = 111 bits (266), Expect = 1e-23
Identities = 60/166 (36%), Positives = 79/166 (47%), Gaps = 18/166 (10%)
Query: 319 KFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHG 375
K C VDYC + H C+ C+N + Y C+C++GF D TC +D C +
Sbjct: 316 KRCVAVDYCASENHGCEHE--CVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSN---- 369
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
H C CVN Y C CL G+T DK C ++ C N GC + C N SY
Sbjct: 370 HGCQHE--CVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHE--CVNMEESYY 425
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CRC GY + +G TC VD C + H C C+N + F C+C
Sbjct: 426 CRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQC 469
Score = 110 bits (265), Expect = 1e-23
Identities = 58/166 (34%), Positives = 82/166 (49%), Gaps = 16/166 (9%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C ++YC + E+ C+N+ Y C+C++G+ D G TC VD C + H
Sbjct: 398 KTCRRINYCALNKPGCEHE-CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQ----QDH 452
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N +VCQC G+ +D C VD C + HGC C N S+ C
Sbjct: 453 GCEQ--LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFAC 508
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+C +G+ DG TC +D C G H C HS CV+ + F C+CF
Sbjct: 509 QCPEGHVLRSDGKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCF 552
Score = 110 bits (264), Expect = 2e-23
Identities = 62/180 (34%), Positives = 86/180 (47%), Gaps = 19/180 (10%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQG--FQGDGLTC 361
C + F + E K C VDYC + H C+ + C+N++ + C+C +G + DG TC
Sbjct: 467 CQCSEGFLI-NEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTC 523
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGC 420
+D C L H C + CV+ +VCQC GY R+D C D C+ HGC
Sbjct: 524 AKLDSC----ALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGC 577
Query: 421 HADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +C N+ SYTC C G+ DG C D C H C H CVN + C+C
Sbjct: 578 --EHICVNSDDSYTCECLVGFRLAEDGKRCRRKDVCKSTHHGCEHI--CVNNGNSYICKC 633
Score = 85.8 bits (203), Expect = 4e-16
Identities = 56/179 (31%), Positives = 79/179 (44%), Gaps = 25/179 (13%)
Query: 285 HDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLN 343
H C +D AC C G K C +D C +G H C+ + C++
Sbjct: 493 HGCEYSCVNMDRSFACQ---CPEGHVLRSDG---KTCAKLDSCALGDHGCEHS--CVSSE 544
Query: 344 TKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT- 400
+ C+C +G+ + DG TC+ D CQ H C CVN Y C+CL G+
Sbjct: 545 DSFVCQCFEGYILREDGKTCRRKDVCQAID----HGCEHI--CVNSDDSYTCECLVGFRL 598
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
+D C D C+ HGC + +C N SY C+C +G+ DG C +CTEG
Sbjct: 599 AEDGKRCRRKDVCKSTHHGC--EHICVNNGNSYICKCSEGFVLAEDGRRC---KKCTEG 652
Score = 59.7 bits (138), Expect = 3e-08
Identities = 28/70 (40%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNI 470
C H C C N PGSY CRC+ GY D TC D C H C CVN+
Sbjct: 242 CSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNV 297
Query: 471 DGGFRCECFT 480
G F C+C++
Sbjct: 298 PGSFVCQCYS 307
Score = 37.1 bits (82), Expect = 0.20
Identities = 29/109 (26%), Positives = 42/109 (38%), Gaps = 9/109 (8%)
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
QC L E G+ K+ + + H C D C C + + G+ C+
Sbjct: 550 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCE---CLVGFRLAEDGKRCR 606
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDE 366
D C H E+ C+N Y CKC++GF DG C+ E
Sbjct: 607 ---RKDVCKSTHHGCEHI-CVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
>BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein.
Length = 937
Score = 118 bits (285), Expect = 5e-26
Identities = 60/165 (36%), Positives = 78/165 (47%), Gaps = 17/165 (10%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
K C + H+C C+N+ Y C+C QG+ D TC+ D C + H
Sbjct: 235 KLCTAHMCSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLC----AMEDH 288
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+C CVNV G +VCQC GY +D CV VD C HGC + C N GSY C
Sbjct: 289 NCEQ--LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHE--CVNADGSYLC 344
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +G+ D TC +D C +H C H CVN D + C C
Sbjct: 345 QCHEGFALNPDEKTCTKIDYCASSNHGCQH--ECVNTDDSYSCHC 387
Score = 112 bits (269), Expect = 4e-24
Identities = 62/180 (34%), Positives = 87/180 (48%), Gaps = 19/180 (10%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQG--FQGDGLTC 361
C + F + E K C VDYC + H C+ + C+N++ + C+C +G + DG TC
Sbjct: 467 CQCSEGFLI-NEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTC 523
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGC 420
+D C L H C + CV+ +VCQC GY R+D C D C+ HGC
Sbjct: 524 AKLDSC----ALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGC 577
Query: 421 HADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +C N+ SYTC C +G+ DG C D C H C H CVN + C+C
Sbjct: 578 --EHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHI--CVNNGNSYICKC 633
Score = 111 bits (266), Expect = 1e-23
Identities = 60/166 (36%), Positives = 79/166 (47%), Gaps = 18/166 (10%)
Query: 319 KFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHG 375
K C VDYC + H C+ C+N + Y C+C++GF D TC +D C +
Sbjct: 316 KRCVAVDYCASENHGCEHE--CVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSN---- 369
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
H C CVN Y C CL G+T DK C ++ C N GC + C N SY
Sbjct: 370 HGCQHE--CVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHE--CVNMEESYY 425
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CRC GY + +G TC VD C + H C C+N + F C+C
Sbjct: 426 CRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQC 469
Score = 110 bits (265), Expect = 1e-23
Identities = 58/166 (34%), Positives = 82/166 (49%), Gaps = 16/166 (9%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C ++YC + E+ C+N+ Y C+C++G+ D G TC VD C + H
Sbjct: 398 KTCRRINYCALNKPGCEHE-CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQ----QDH 452
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N +VCQC G+ +D C VD C + HGC C N S+ C
Sbjct: 453 GCEQ--LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFAC 508
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+C +G+ DG TC +D C G H C HS CV+ + F C+CF
Sbjct: 509 QCPEGHVLRSDGKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCF 552
Score = 86.2 bits (204), Expect = 3e-16
Identities = 56/179 (31%), Positives = 79/179 (44%), Gaps = 25/179 (13%)
Query: 285 HDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLN 343
H C +D AC C G K C +D C +G H C+ + C++
Sbjct: 493 HGCEYSCVNMDRSFACQ---CPEGHVLRSDG---KTCAKLDSCALGDHGCEHS--CVSSE 544
Query: 344 TKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT- 400
+ C+C +G+ + DG TC+ D CQ H C CVN Y C+CL G+
Sbjct: 545 DSFVCQCFEGYILREDGKTCRRKDVCQAID----HGCEHI--CVNSDDSYTCECLEGFRL 598
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
+D C D C+ HGC + +C N SY C+C +G+ DG C +CTEG
Sbjct: 599 AEDGKRCRRKDVCKSTHHGC--EHICVNNGNSYICKCSEGFVLAEDGRRC---KKCTEG 652
Score = 59.7 bits (138), Expect = 3e-08
Identities = 28/70 (40%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNI 470
C H C C N PGSY CRC+ GY D TC D C H C CVN+
Sbjct: 242 CSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNV 297
Query: 471 DGGFRCECFT 480
G F C+C++
Sbjct: 298 PGSFVCQCYS 307
Score = 38.3 bits (85), Expect = 0.084
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 9/109 (8%)
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
QC L E G+ K+ + + H C D C L + F + E K
Sbjct: 550 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECL-----EGFRL-AEDGK 603
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDE 366
C D C H E+ C+N Y CKC++GF DG C+ E
Sbjct: 604 RCRRKDVCKSTHHGCEHI-CVNNGNSYICKCSEGFVLAEDGRRCKKCTE 651
>AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein
protein.
Length = 1016
Score = 118 bits (285), Expect = 5e-26
Identities = 60/165 (36%), Positives = 78/165 (47%), Gaps = 17/165 (10%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
K C + H+C C+N+ Y C+C QG+ D TC+ D C + H
Sbjct: 295 KLCTAHMCSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLC----AMEDH 348
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+C CVNV G +VCQC GY +D CV VD C HGC + C N GSY C
Sbjct: 349 NCEQ--LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHE--CVNADGSYLC 404
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +G+ D TC +D C +H C H CVN D + C C
Sbjct: 405 QCHEGFALNPDEKTCTKIDYCASSNHGCQH--ECVNTDDSYSCHC 447
Score = 112 bits (269), Expect = 4e-24
Identities = 62/180 (34%), Positives = 87/180 (48%), Gaps = 19/180 (10%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQG--FQGDGLTC 361
C + F + E K C VDYC + H C+ + C+N++ + C+C +G + DG TC
Sbjct: 527 CQCSEGFLI-NEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTC 583
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGC 420
+D C L H C + CV+ +VCQC GY R+D C D C+ HGC
Sbjct: 584 AKLDSC----ALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGC 637
Query: 421 HADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +C N+ SYTC C +G+ DG C D C H C H CVN + C+C
Sbjct: 638 --EHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHI--CVNNGNSYICKC 693
Score = 111 bits (266), Expect = 1e-23
Identities = 60/166 (36%), Positives = 79/166 (47%), Gaps = 18/166 (10%)
Query: 319 KFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHG 375
K C VDYC + H C+ C+N + Y C+C++GF D TC +D C +
Sbjct: 376 KRCVAVDYCASENHGCEHE--CVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSN---- 429
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
H C CVN Y C CL G+T DK C ++ C N GC + C N SY
Sbjct: 430 HGCQHE--CVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHE--CVNMEESYY 485
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CRC GY + +G TC VD C + H C C+N + F C+C
Sbjct: 486 CRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQC 529
Score = 110 bits (265), Expect = 1e-23
Identities = 58/166 (34%), Positives = 82/166 (49%), Gaps = 16/166 (9%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C ++YC + E+ C+N+ Y C+C++G+ D G TC VD C + H
Sbjct: 458 KTCRRINYCALNKPGCEHE-CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQ----QDH 512
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N +VCQC G+ +D C VD C + HGC C N S+ C
Sbjct: 513 GCEQ--LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFAC 568
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+C +G+ DG TC +D C G H C HS CV+ + F C+CF
Sbjct: 569 QCPEGHVLRSDGKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCF 612
Score = 86.2 bits (204), Expect = 3e-16
Identities = 56/179 (31%), Positives = 79/179 (44%), Gaps = 25/179 (13%)
Query: 285 HDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLN 343
H C +D AC C G K C +D C +G H C+ + C++
Sbjct: 553 HGCEYSCVNMDRSFACQ---CPEGHVLRSDG---KTCAKLDSCALGDHGCEHS--CVSSE 604
Query: 344 TKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT- 400
+ C+C +G+ + DG TC+ D CQ H C CVN Y C+CL G+
Sbjct: 605 DSFVCQCFEGYILREDGKTCRRKDVCQAID----HGCEHI--CVNSDDSYTCECLEGFRL 658
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
+D C D C+ HGC + +C N SY C+C +G+ DG C +CTEG
Sbjct: 659 AEDGKRCRRKDVCKSTHHGC--EHICVNNGNSYICKCSEGFVLAEDGRRC---KKCTEG 712
Score = 59.7 bits (138), Expect = 3e-08
Identities = 28/70 (40%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNI 470
C H C C N PGSY CRC+ GY D TC D C H C CVN+
Sbjct: 302 CSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNV 357
Query: 471 DGGFRCECFT 480
G F C+C++
Sbjct: 358 PGSFVCQCYS 367
Score = 38.3 bits (85), Expect = 0.084
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 9/109 (8%)
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
QC L E G+ K+ + + H C D C L + F + E K
Sbjct: 610 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECL-----EGFRL-AEDGK 663
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDE 366
C D C H E+ C+N Y CKC++GF DG C+ E
Sbjct: 664 RCRRKDVCKSTHHGCEHI-CVNNGNSYICKCSEGFVLAEDGRRCKKCTE 711
>AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein.
Length = 451
Score = 118 bits (285), Expect = 5e-26
Identities = 60/165 (36%), Positives = 78/165 (47%), Gaps = 17/165 (10%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
K C + H+C C+N+ Y C+C QG+ D TC+ D C + H
Sbjct: 235 KLCTAHMCSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLC----AMEDH 288
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+C CVNV G +VCQC GY +D CV VD C HGC + C N GSY C
Sbjct: 289 NCEQ--LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHE--CVNADGSYLC 344
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +G+ D TC +D C +H C H CVN D + C C
Sbjct: 345 QCHEGFALNPDKKTCTKIDYCASSNHGCQH--ECVNTDDSYSCHC 387
Score = 91.5 bits (217), Expect = 9e-18
Identities = 54/145 (37%), Positives = 69/145 (47%), Gaps = 18/145 (12%)
Query: 319 KFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHG 375
K C VDYC + H C+ C+N + Y C+C++GF D TC +D C +
Sbjct: 316 KRCVAVDYCASENHGCEHE--CVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSN---- 369
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
H C CVN Y C CL G+T DK C ++ C N GC + C N SY
Sbjct: 370 HGCQHE--CVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHE--CVNMEESYY 425
Query: 435 CRCRDGY--EGDGYTCMHVDECTEG 457
CRC GY + +G TC ECT G
Sbjct: 426 CRCHRGYTLDPNGKTCSR--ECTLG 448
Score = 59.7 bits (138), Expect = 3e-08
Identities = 28/70 (40%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNI 470
C H C C N PGSY CRC+ GY D TC D C H C CVN+
Sbjct: 242 CSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNV 297
Query: 471 DGGFRCECFT 480
G F C+C++
Sbjct: 298 PGSFVCQCYS 307
>AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens
cDNA FLJ14438 fis, clone HEMBB1000317, weakly similar to
FIBULIN-1, ISOFORM D PRECURSOR. ).
Length = 741
Score = 118 bits (285), Expect = 5e-26
Identities = 57/162 (35%), Positives = 80/162 (49%), Gaps = 15/162 (9%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 413 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 464
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT GSY C C
Sbjct: 465 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCP 524
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM +DEC E + C H C N G ++C C
Sbjct: 525 RGYRSQGVGRPCMDIDEC-ENTDACQH--ECKNTFGSYQCIC 563
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 327 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 380
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 381 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 437
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 438 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 477
Score = 101 bits (241), Expect = 1e-20
Identities = 86/282 (30%), Positives = 118/282 (41%), Gaps = 39/282 (13%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 354 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 401
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 402 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 450
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 451 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 505
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C+++DECE NT C + C NT GSY C
Sbjct: 506 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECE-NTDACQHE--CKNTFGSYQCI 562
Query: 437 CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C GY+ +G TC +DEC E + C + C N+ G ++C
Sbjct: 563 CPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 604
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 314 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 366
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 367 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 425
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 426 HQ--RCFNAIGSFHCGC 440
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 118 bits (285), Expect = 5e-26
Identities = 56/162 (34%), Positives = 79/162 (48%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS 380
C ++ C C + C N + C C G+Q G C DV+EC++ + C
Sbjct: 5191 CQDINECQESSPCHQR--CFNAIGSFHCGCEPGYQLKGRKCMDVNECRQ------NVCRP 5242
Query: 381 NTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ C N GGY C C G T+ + C+++DEC+ TH C + +C NT SY C C
Sbjct: 5243 DQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRSSYRCVCP 5302
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY +G G CM +DEC + C H +C N G F+C C
Sbjct: 5303 RGYRSQGVGRPCMDIDECEQVPKPCAH--QCSNTPGSFKCIC 5342
Score = 112 bits (270), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
FC D C G+ C + C N Y C C +G DG TCQD+DEC L H
Sbjct: 5105 FCADEDECAAGNPCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC----ALGRHT 5158
Query: 378 CHSNTRCVNVVGGYVC--QCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CH+ C N +G Y C +C G+ R D +C +++EC+ + CH C N GS+
Sbjct: 5159 CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQ-ESSPCHQR--CFNAIGSFH 5215
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 5216 CGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 5255
Score = 96.3 bits (229), Expect = 3e-19
Identities = 57/137 (41%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 349 KCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
+C GF D G C D DEC AG H CH N +G Y C C G T D
Sbjct: 5092 QCPSGFTLDSVGPFCADEDECA-AGNPCSHSCH------NAMGTYYCSCPKGLTIAADGR 5144
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE--GDGYTCMHVDECTEGSHTC 461
C ++DEC H CHA C NT GSY C RC G+ DG +C ++EC E S C
Sbjct: 5145 TCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESS-PC 5203
Query: 462 HHSARCVNIDGGFRCEC 478
H RC N G F C C
Sbjct: 5204 HQ--RCFNAIGSFHCGC 5218
Score = 74.5 bits (175), Expect = 1e-12
Identities = 74/254 (29%), Positives = 100/254 (39%), Gaps = 38/254 (14%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL 262
SC T+ ADG T Q D + C+ G TC + +C N + G C+ +C
Sbjct: 5132 SCPKGLTIAADGRTCQ-DIDECAL--GRHTCHAGQ----DCDNTI---GSY--RCVVRCG 5179
Query: 263 LWGNLYEHGERFAP-KECAECV-CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKF 320
G EC E CH +C C C+P Q +
Sbjct: 5180 SGFRRTSDGLSCQDINECQESSPCHQ---RCFNAIGSFHCG---CEPGYQLKG-----RK 5228
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 5229 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 5283
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N Y C C GY + C+++DECE C C+NTPGS+ C
Sbjct: 5284 CRYNQICENTRSSYRCVCPRGYRSQGVGRPCMDIDECEQVPKPCAHQ--CSNTPGSFKCI 5341
Query: 437 CRDGYE--GDGYTC 448
C G GDG +C
Sbjct: 5342 CPPGQHLLGDGKSC 5355
Score = 66.9 bits (156), Expect = 2e-10
Identities = 31/72 (43%), Positives = 42/72 (58%), Gaps = 5/72 (6%)
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
CV++DECE NT C + C NT GSY C C GY+ +G TC +DEC E + C +
Sbjct: 5431 CVDIDECE-NTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPN 5487
Query: 465 ARCVNIDGGFRC 476
C N+ G ++C
Sbjct: 5488 RMCFNMRGSYQC 5499
Score = 57.6 bits (133), Expect = 1e-07
Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY--TRKDKFNC 407
C +G + TC D+DEC+ C C N G Y C C GY T K C
Sbjct: 5420 CPEGSEASHDTCVDIDECENTDA-----CQH--ECKNTFGSYQCICPPGYQLTHNGK-TC 5471
Query: 408 VEVDEC-EGNTHGCHADAVCTNTPGSYTC---RCRDGYEGDGYTCMHVDECTEGSHTC 461
++DEC E N H C + +C N GSY C C Y+ D + + C C
Sbjct: 5472 QDIDECLEQNVH-CGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLEC 5528
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C +C C N Y C C G+Q +G TCQD+DEC E HC
Sbjct: 5431 CVDIDECENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLE----QNVHC 5484
Query: 379 HSNTRCVNVVGGYVC 393
N C N+ G Y C
Sbjct: 5485 GPNRMCFNMRGSYQC 5499
>X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein.
Length = 1184
Score = 118 bits (284), Expect = 7e-26
Identities = 70/201 (34%), Positives = 91/201 (45%), Gaps = 18/201 (8%)
Query: 284 CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNL 342
C G C C R P + + + K C V+ C G H C E C NL
Sbjct: 821 CRPG-FSCINTVGSYTCQRNPLICARGYHASDDGAK-CVDVNECETGVHRCGEGQVCHNL 878
Query: 343 NTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
Y C C GFQ D G C DV+EC + G H C N +G Y C C G+
Sbjct: 879 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT-----CENTLGSYRCSCASGFL 933
Query: 401 -RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEG 457
D C +V+ECE C + C N GSY C CR GY+ DG+TC +DEC +G
Sbjct: 934 LAADGKRCEDVNECEAQR--CSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQG 989
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
+ + RC+N+ G ++C C
Sbjct: 990 AGILC-TFRCLNVPGSYQCAC 1009
Score = 111 bits (266), Expect = 1e-23
Identities = 63/173 (36%), Positives = 78/173 (45%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTC----KCNQGFQGDGL-TCQDVDECQEAGGLH 374
C VD C MG H+C C N + C +C GF D C D++EC
Sbjct: 762 CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLS--- 818
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTN 428
C C+N VG Y CQ C GY D CV+V+ECE H C VC N
Sbjct: 819 -EPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHN 877
Query: 429 TPGSYTCRCRDGYEGD--GYTCMHVDEC-TEGSHTCHHSARCVNIDGGFRCEC 478
PGSY C C+ G++ D G C+ V+EC C H+ C N G +RC C
Sbjct: 878 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT--CENTLGSYRCSC 928
Score = 107 bits (258), Expect = 9e-23
Identities = 61/164 (37%), Positives = 76/164 (46%), Gaps = 19/164 (11%)
Query: 321 CPGVDYC--NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
C V+ C + G C TC N Y C C GF DG C+DV+EC+
Sbjct: 899 CIDVNECWASPGRLCQH--TCENTLGSYRCSCASGFLLAADGKRCEDVNECE------AQ 950
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C + C N+ G Y C C GY +D C ++DEC G C N PGSY C
Sbjct: 951 RC--SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGA-GILCTFRCLNVPGSYQC 1007
Query: 436 RCRD-GYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C + GY +G +C VDEC G+H C + C NI G FRC
Sbjct: 1008 ACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1051
Score = 97.1 bits (231), Expect = 2e-19
Identities = 54/167 (32%), Positives = 75/167 (44%), Gaps = 18/167 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCH 379
P + C C + C + C C G+ DG++C+D++EC H C
Sbjct: 678 PQPNTCKDNGPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDINECV----TDLHTCS 731
Query: 380 SNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
CVN +G + C C GY KD C +VDEC TH C +C NT GS+ C
Sbjct: 732 RGEHCVNTLGSFHCYKALTCEPGYALKDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYC 790
Query: 436 ----RCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCE 477
RC DG+ D C+ ++ECT S C C+N G + C+
Sbjct: 791 QARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQ 837
Score = 58.8 bits (136), Expect = 6e-08
Identities = 67/267 (25%), Positives = 102/267 (38%), Gaps = 36/267 (13%)
Query: 177 HIHDLSLKLVGAEARISRLEQCDCQKSCYS-NGTVHAD-GATWQRDCNRCSCVH-GEITC 233
H D K V + + +C + C++ G+ D A +QRD C+ E
Sbjct: 848 HASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 907
Query: 234 RPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTR 293
P + C+N + G +C LL + G+R ++ EC + +C
Sbjct: 908 SPGRLCQHTCENTL---GSYRCSCASGFLLAAD----GKRC--EDVNECEAQRCSQECAN 958
Query: 294 VDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKC-NQ 352
+ C C Q + G C +D C G C+N+ Y C C Q
Sbjct: 959 IYGSYQCY---CRQGYQLAEDGHTCT---DIDECAQGAGILCTFRCLNVPGSYQCACPEQ 1012
Query: 353 GFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC---QCLGGYTRKDKFNC 407
G+ +G +C+DVDEC L H+C C N+ G + C +C Y + K
Sbjct: 1013 GYTMTANGRSCKDVDEC----ALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK--- 1065
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYT 434
+CE T CH C N+P T
Sbjct: 1066 ---TKCERTT--CHDFLECQNSPARIT 1087
Score = 35.5 bits (78), Expect = 0.60
Identities = 40/151 (26%), Positives = 54/151 (35%), Gaps = 22/151 (14%)
Query: 233 CRPVECDRAE-CKNPVLHPGECCPTCLRQ-----------CL----LWGNLYEHGERFAP 276
C VEC E C L PG CC TC++Q CL + G + F
Sbjct: 33 CTGVECPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCLQGGFVRGRVPAGQSYFVD 92
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
EC C G + + + CP LP + + V + C C V + GH
Sbjct: 93 FGSTECSCPPGGGKIS--CQFMLCPELPPNCIEAV-VVADSCPQCGQVGCVHAGHEYAAG 149
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDEC 367
T ++L C C G L C + C
Sbjct: 150 HT-VHLPPCRACHCPDA--GGELICYQLPGC 177
>BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein.
Length = 1184
Score = 118 bits (284), Expect = 7e-26
Identities = 70/201 (34%), Positives = 91/201 (45%), Gaps = 18/201 (8%)
Query: 284 CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNL 342
C G C C R P + + + K C V+ C G H C E C NL
Sbjct: 821 CRPG-FSCINTVGSYTCQRNPLICARGYHASDDGAK-CVDVNECETGVHRCGEGQVCHNL 878
Query: 343 NTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
Y C C GFQ D G C DV+EC + G H C N +G Y C C G+
Sbjct: 879 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT-----CENTLGSYRCSCASGFL 933
Query: 401 -RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEG 457
D C +V+ECE C + C N GSY C CR GY+ DG+TC +DEC +G
Sbjct: 934 LAADGKRCEDVNECEAQR--CSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQG 989
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
+ + RC+N+ G ++C C
Sbjct: 990 AGILC-TFRCLNVPGSYQCAC 1009
Score = 111 bits (266), Expect = 1e-23
Identities = 63/173 (36%), Positives = 78/173 (45%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTC----KCNQGFQGDGL-TCQDVDECQEAGGLH 374
C VD C MG H+C C N + C +C GF D C D++EC
Sbjct: 762 CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLS--- 818
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTN 428
C C+N VG Y CQ C GY D CV+V+ECE H C VC N
Sbjct: 819 -EPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHN 877
Query: 429 TPGSYTCRCRDGYEGD--GYTCMHVDEC-TEGSHTCHHSARCVNIDGGFRCEC 478
PGSY C C+ G++ D G C+ V+EC C H+ C N G +RC C
Sbjct: 878 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT--CENTLGSYRCSC 928
Score = 107 bits (258), Expect = 9e-23
Identities = 61/164 (37%), Positives = 76/164 (46%), Gaps = 19/164 (11%)
Query: 321 CPGVDYC--NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
C V+ C + G C TC N Y C C GF DG C+DV+EC+
Sbjct: 899 CIDVNECWASPGRLCQH--TCENTLGSYRCSCASGFLLAADGKRCEDVNECE------AQ 950
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C + C N+ G Y C C GY +D C ++DEC G C N PGSY C
Sbjct: 951 RC--SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGA-GILCTFRCLNVPGSYQC 1007
Query: 436 RCRD-GYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C + GY +G +C VDEC G+H C + C NI G FRC
Sbjct: 1008 ACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1051
Score = 97.1 bits (231), Expect = 2e-19
Identities = 54/167 (32%), Positives = 75/167 (44%), Gaps = 18/167 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCH 379
P + C C + C + C C G+ DG++C+D++EC H C
Sbjct: 678 PQPNTCKDNGPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDINECV----TDLHTCS 731
Query: 380 SNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
CVN +G + C C GY KD C +VDEC TH C +C NT GS+ C
Sbjct: 732 RGEHCVNTLGSFHCYKALTCEPGYALKDG-ECEDVDECAMGTHTCQPGFLCQNTKGSFYC 790
Query: 436 ----RCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCE 477
RC DG+ D C+ ++ECT S C C+N G + C+
Sbjct: 791 QARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQ 837
Score = 58.8 bits (136), Expect = 6e-08
Identities = 67/267 (25%), Positives = 102/267 (38%), Gaps = 36/267 (13%)
Query: 177 HIHDLSLKLVGAEARISRLEQCDCQKSCYS-NGTVHAD-GATWQRDCNRCSCVH-GEITC 233
H D K V + + +C + C++ G+ D A +QRD C+ E
Sbjct: 848 HASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 907
Query: 234 RPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTR 293
P + C+N + G +C LL + G+R ++ EC + +C
Sbjct: 908 SPGRLCQHTCENTL---GSYRCSCASGFLLAAD----GKRC--EDVNECEAQRCSQECAN 958
Query: 294 VDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKC-NQ 352
+ C C Q + G C +D C G C+N+ Y C C Q
Sbjct: 959 IYGSYQCY---CRQGYQLAEDGHTCT---DIDECAQGAGILCTFRCLNVPGSYQCACPEQ 1012
Query: 353 GFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC---QCLGGYTRKDKFNC 407
G+ +G +C+DVDEC L H+C C N+ G + C +C Y + K
Sbjct: 1013 GYTMTANGRSCKDVDEC----ALGTHNCSEAETCHNIQGSFRCLRLECPPNYVQVSK--- 1065
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYT 434
+CE T CH C N+P T
Sbjct: 1066 ---TKCERTT--CHDFLECQNSPARIT 1087
Score = 35.5 bits (78), Expect = 0.60
Identities = 40/151 (26%), Positives = 54/151 (35%), Gaps = 22/151 (14%)
Query: 233 CRPVECDRAE-CKNPVLHPGECCPTCLRQ-----------CL----LWGNLYEHGERFAP 276
C VEC E C L PG CC TC++Q CL + G + F
Sbjct: 33 CTGVECPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCLQGGFVRGRVPAGQSYFVD 92
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
EC C G + + + CP LP + + V + C C V + GH
Sbjct: 93 FGSTECSCPPGGGKIS--CQFMLCPELPPNCIEAV-VVADSCPQCGQVGCVHAGHKYAAG 149
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDEC 367
T ++L C C G L C + C
Sbjct: 150 HT-VHLPPCRACHCPDA--GGELICYQLPGC 177
>AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant
protein.
Length = 830
Score = 118 bits (284), Expect = 7e-26
Identities = 81/242 (33%), Positives = 111/242 (45%), Gaps = 31/242 (12%)
Query: 250 PGECCPT----CLRQCLLWGNLYEHGERFAPKECAEC----VCHDGNMQCTRVDPELACP 301
P E CPT RQ +G+ G + + EC VC G QC D C
Sbjct: 530 PCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHG--QCINTDGSYRCE 587
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-GDGLT 360
C P + + G C D C++G+ C N TC N+ + C C +GF+ G +T
Sbjct: 588 ---C--PFGYILAGN---ECVDTDECSVGNPCG-NGTCKNVIGGFECTCEEGFEPGPMMT 638
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHG 419
C+D++EC + L RCVN G Y C+C GY R+D+ C + DECE H
Sbjct: 639 CEDINECAQNPLLCAF------RCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHD 692
Query: 420 CHADAV-CTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C + C N G+Y C C GY+ DG C+ +EC C + RC+N G + C
Sbjct: 693 CTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGIC-ENGRCLNTRGSYTC 751
Query: 477 EC 478
EC
Sbjct: 752 EC 753
Score = 115 bits (277), Expect = 5e-25
Identities = 55/161 (34%), Positives = 83/161 (51%), Gaps = 11/161 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGL-TCQDVDECQEAGGLHGHHCH 379
C +D C G C NA C+N Y C C G++ C D +ECQE + C
Sbjct: 241 CEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNI----C- 295
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+ +C++ VG + C C G+ T D+ C++++ECE + G + C NT GS+ CRC
Sbjct: 296 SHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACG---NGTCRNTIGSFNCRCN 352
Query: 439 DGY-EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ C+ VDEC G+ + +C+N G F+C+C
Sbjct: 353 HGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQC 393
Score = 108 bits (259), Expect = 7e-23
Identities = 64/170 (37%), Positives = 80/170 (47%), Gaps = 11/170 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF-QGDGLTCQDVDECQEAGGLHGHHCH 379
C ++ C +C N TC N + C+CN GF C DVDEC A G +G+ C
Sbjct: 324 CLDINECERD-ACG-NGTCRNTIGSFNCRCNHGFILSHNNDCIDVDEC--ASG-NGNLCR 378
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
N +C+N VG + CQC GY D CV+++EC C A C N GSY C C
Sbjct: 379 -NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC-APGTCQNLDGSYRCICP 436
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
GY C +DEC E C C N +G F+C C E LS S
Sbjct: 437 PGYSLQNEKCEDIDECVEEPEIC-ALGTCSNTEGSFKCLC-PEGFSLSSS 484
Score = 103 bits (248), Expect = 2e-21
Identities = 64/211 (30%), Positives = 97/211 (45%), Gaps = 31/211 (14%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGEC-----CKFCPGVDYCNMGHS 332
EC N +C C C P +F+ G+C C+ P + C+ G
Sbjct: 246 ECQNGPVCQRNAECINTAGSYRCD---CKPGYRFTSTGQCNDRNECQEIPNI--CSHGQ- 299
Query: 333 CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C++ + C C+ GF+ D C D++EC+ C + T C N +G
Sbjct: 300 ------CIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDA------CGNGT-CRNTIGS 346
Query: 391 YVCQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYT 447
+ C+C G+ +C++VDEC GN + C + C NT GS+ C+C +GYE DG T
Sbjct: 347 FNCRCNHGFILSHNNDCIDVDECASGNGNLCR-NGQCINTVGSFQCQCNEGYEVAPDGRT 405
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+ ++EC C C N+DG +RC C
Sbjct: 406 CVDINECLLEPRKC-APGTCQNLDGSYRCIC 435
Score = 93.9 bits (223), Expect = 2e-18
Identities = 50/159 (31%), Positives = 73/159 (45%), Gaps = 13/159 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSN 381
+D C EN C+N+ + C+C GF L C+D+DECQ +G C N
Sbjct: 202 IDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-----NGPVCQRN 256
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N G Y C C GY C + +EC+ + C + C +T GS+ C C G+
Sbjct: 257 AECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC-SHGQCIDTVGSFYCLCHTGF 315
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ D C+ ++EC + C + C N G F C C
Sbjct: 316 KTNDDQTMCLDINECERDA--CGNGT-CRNTIGSFNCRC 351
Score = 87.0 bits (206), Expect = 2e-16
Identities = 45/120 (37%), Positives = 64/120 (53%), Gaps = 9/120 (7%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCH 421
D+DEC+E G+ C + C+N+VG + C+C G+ DK C ++DEC+ N C
Sbjct: 201 DIDECREIPGV----CENGV-CINMVGSFRCECPVGFFYNDKLLVCEDIDECQ-NGPVCQ 254
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+A C NT GSY C C+ GY C +EC E + C H +C++ G F C C T
Sbjct: 255 RNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSH-GQCIDTVGSFYCLCHT 313
Score = 82.2 bits (194), Expect = 5e-15
Identities = 42/107 (39%), Positives = 56/107 (52%), Gaps = 9/107 (8%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYVCQC 395
C+N Y CKC G+ + D C+D DEC+E H C C N++G Y+C C
Sbjct: 656 CVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGK----HDCTEKQMECKNLIGTYMCIC 711
Query: 396 LGGYTRK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
GY R+ D CV+ +EC+ C + C NT GSYTC C DG+
Sbjct: 712 GPGYQRRPDGEGCVDENECQTKPGICE-NGRCLNTRGSYTCECNDGF 757
Score = 70.1 bits (164), Expect = 2e-11
Identities = 44/119 (36%), Positives = 59/119 (49%), Gaps = 15/119 (12%)
Query: 339 CMNLNT---KYTCKCNQGFQGDGLTC--QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C +NT K C +GF+ + +T +D+DECQE GL C +C+N G + C
Sbjct: 12 CPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL----CQGG-KCINTFGSFQC 66
Query: 394 QC-LGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCM 449
+C G Y +D C +V+ECE T G C NT G+YTC C Y G CM
Sbjct: 67 RCPTGYYLNEDTRVCDDVNECE--TPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCM 123
Score = 62.1 bits (144), Expect = 6e-09
Identities = 67/238 (28%), Positives = 93/238 (39%), Gaps = 33/238 (13%)
Query: 185 LVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECK 244
+VG + +++C C ++ DG+ RC C G I D EC
Sbjct: 553 IVGPDDSAVDMDECKEPDVCKHGQCINTDGSY------RCECPFGYILAGNECVDTDECS 606
Query: 245 NPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRL- 303
G C + ++ G E F P C D N +C + +P L R
Sbjct: 607 -----VGNPCGNGTCKNVIGGFECTCEEGFEPGPMM--TCEDIN-ECAQ-NPLLCAFRCV 657
Query: 304 ------PCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENAT-CMNLNTKYTCKCNQGFQ 355
C P + V E + C D C G H C E C NL Y C C G+Q
Sbjct: 658 NTYGSYECKCPVGY-VLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQ 716
Query: 356 G--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEV 410
DG C D +ECQ G+ C N RC+N G Y C+C G+T ++ C++V
Sbjct: 717 RRPDGEGCVDENECQTKPGI----CE-NGRCLNTRGSYTCECNDGFTASPNQDECLDV 769
Score = 43.2 bits (97), Expect = 0.003
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC+ C C NT GS+ CRC GY D C V+EC E C
Sbjct: 41 DIDECQELPGLCQGGK-CINTFGSFQCRCPTGYYLNEDTRVCDDVNEC-ETPGIC-GPGT 97
Query: 467 CVNIDGGFRCEC 478
C N G + C C
Sbjct: 98 CYNTVGNYTCIC 109
Score = 43.2 bits (97), Expect = 0.003
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 9/90 (10%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSN 381
+D C + C+N + C+C G+ D C DV+EC+ G C
Sbjct: 42 IDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPG-----ICGPG 96
Query: 382 TRCVNVVGGYVCQCLGGYTR-KDKFNCVEV 410
T C N VG Y C C Y + NC+++
Sbjct: 97 T-CYNTVGNYTCICPPDYMQVNGGNNCMDM 125
>X94630-1|CAA64333.1| 835|Homo sapiens seven-span transmembrane
protein protein.
Length = 835
Score = 118 bits (283), Expect = 9e-26
Identities = 64/167 (38%), Positives = 81/167 (48%), Gaps = 24/167 (14%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 75 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 130
Query: 382 TRCVNVVGGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ +D C +V+EC + CH+ C N GSY CRCR
Sbjct: 131 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 190
Query: 440 GYE-------GDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G++ G T C VDEC+ G H C S C N G + C C
Sbjct: 191 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 237
Score = 103 bits (248), Expect = 2e-21
Identities = 55/165 (33%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C +N++C+N C+CN GF TC D++EC + C + C
Sbjct: 30 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVS---CGKFSDCW 83
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 84 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 143
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 144 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 188
Score = 99 bits (238), Expect = 2e-20
Identities = 51/133 (38%), Positives = 66/133 (49%), Gaps = 15/133 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ---GDGLTCQDVDECQEAGGLHGH 376
C VD C C TC+N YTC+C GF+ D C DV+EC +
Sbjct: 114 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQ----N 169
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-------TRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
CHS+T C+N VG Y C+C G+ + C +VDEC H C + VC NT
Sbjct: 170 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 229
Query: 430 PGSYTCRCRDGYE 442
GSY+CRCR G++
Sbjct: 230 VGSYSCRCRPGWK 242
>U76764-1|AAB36682.1| 835|Homo sapiens CD97 protein.
Length = 835
Score = 118 bits (283), Expect = 9e-26
Identities = 64/167 (38%), Positives = 81/167 (48%), Gaps = 24/167 (14%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 75 SCGKFSDCWNTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRL----CKSY 130
Query: 382 TRCVNVVGGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ +D C +V+EC + CH+ C N GSY CRCR
Sbjct: 131 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 190
Query: 440 GYE-------GDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G++ G T C VDEC+ G H C S C N G + C C
Sbjct: 191 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 237
Score = 103 bits (248), Expect = 2e-21
Identities = 55/165 (33%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C +N++C+N C+CN GF TC D++EC + C + C
Sbjct: 30 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVS---CGKFSDCW 83
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 84 NTEGSYDCVCSPGYEPVSGTKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 143
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 144 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 188
Score = 99 bits (238), Expect = 2e-20
Identities = 51/133 (38%), Positives = 66/133 (49%), Gaps = 15/133 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ---GDGLTCQDVDECQEAGGLHGH 376
C VD C C TC+N YTC+C GF+ D C DV+EC +
Sbjct: 114 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQ----N 169
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-------TRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
CHS+T C+N VG Y C+C G+ + C +VDEC H C + VC NT
Sbjct: 170 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 229
Query: 430 PGSYTCRCRDGYE 442
GSY+CRCR G++
Sbjct: 230 VGSYSCRCRPGWK 242
>BC127005-1|AAI27006.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 118 bits (283), Expect = 9e-26
Identities = 64/167 (38%), Positives = 81/167 (48%), Gaps = 24/167 (14%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 78 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 133
Query: 382 TRCVNVVGGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ +D C +V+EC + CH+ C N GSY CRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 440 GYE-------GDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G++ G T C VDEC+ G H C S C N G + C C
Sbjct: 194 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240
Score = 101 bits (243), Expect = 6e-21
Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C ++++C+N C+CN GF TC D++EC + C + C
Sbjct: 33 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVS---CGKFSDCW 86
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 147 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 191
Score = 99 bits (238), Expect = 2e-20
Identities = 51/133 (38%), Positives = 66/133 (49%), Gaps = 15/133 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ---GDGLTCQDVDECQEAGGLHGH 376
C VD C C TC+N YTC+C GF+ D C DV+EC +
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQ----N 172
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-------TRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
CHS+T C+N VG Y C+C G+ + C +VDEC H C + VC NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 430 PGSYTCRCRDGYE 442
GSY+CRCR G++
Sbjct: 233 VGSYSCRCRPGWK 245
>BC127004-1|AAI27005.1| 823|Homo sapiens egf-like module
containing, mucin-like, hormone receptor-like 2 protein.
Length = 823
Score = 118 bits (283), Expect = 9e-26
Identities = 64/167 (38%), Positives = 81/167 (48%), Gaps = 24/167 (14%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 78 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 133
Query: 382 TRCVNVVGGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ +D C +V+EC + CH+ C N GSY CRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 440 GYE-------GDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G++ G T C VDEC+ G H C S C N G + C C
Sbjct: 194 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240
Score = 101 bits (243), Expect = 6e-21
Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C ++++C+N C+CN GF TC D++EC + C + C
Sbjct: 33 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVS---CGKFSDCW 86
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 147 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 191
Score = 99 bits (238), Expect = 2e-20
Identities = 51/133 (38%), Positives = 66/133 (49%), Gaps = 15/133 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ---GDGLTCQDVDECQEAGGLHGH 376
C VD C C TC+N YTC+C GF+ D C DV+EC +
Sbjct: 117 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQ----N 172
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-------TRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
CHS+T C+N VG Y C+C G+ + C +VDEC H C + VC NT
Sbjct: 173 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 232
Query: 430 PGSYTCRCRDGYE 442
GSY+CRCR G++
Sbjct: 233 VGSYSCRCRPGWK 245
>AB065966-1|BAC06178.1| 837|Homo sapiens seven transmembrane helix
receptor protein.
Length = 837
Score = 118 bits (283), Expect = 9e-26
Identities = 64/167 (38%), Positives = 81/167 (48%), Gaps = 24/167 (14%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 77 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 132
Query: 382 TRCVNVVGGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ +D C +V+EC + CH+ C N GSY CRCR
Sbjct: 133 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 192
Query: 440 GYE-------GDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G++ G T C VDEC+ G H C S C N G + C C
Sbjct: 193 GWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 239
Score = 103 bits (248), Expect = 2e-21
Identities = 55/165 (33%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C +N++C+N C+CN GF TC D++EC + C + C
Sbjct: 32 CPQNSSCVNATA---CRCNPGFSSFSEIITTPTETCDDINECATPSKVS---CGKFSDCW 85
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 86 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 145
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 146 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 190
Score = 99 bits (238), Expect = 2e-20
Identities = 51/133 (38%), Positives = 66/133 (49%), Gaps = 15/133 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ---GDGLTCQDVDECQEAGGLHGH 376
C VD C C TC+N YTC+C GF+ D C DV+EC +
Sbjct: 116 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQ----N 171
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-------TRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
CHS+T C+N VG Y C+C G+ + C +VDEC H C + VC NT
Sbjct: 172 PCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNT 231
Query: 430 PGSYTCRCRDGYE 442
GSY+CRCR G++
Sbjct: 232 VGSYSCRCRPGWK 244
>U03877-1|AAA65590.1| 387|Homo sapiens extracellular protein
protein.
Length = 387
Score = 117 bits (282), Expect = 1e-25
Identities = 58/162 (35%), Positives = 82/162 (50%), Gaps = 16/162 (9%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C G H+C + C+NL + C+C G+Q G C D+DEC +CH
Sbjct: 65 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIP-----PYCH 119
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN G + CQC G+ + + CV+++EC+ + C C N GS+ C+C
Sbjct: 120 Q--RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQ--CYNILGSFICQCN 174
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE D C +DEC S+ C + +CVN G F C C
Sbjct: 175 QGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEPGKFSCMC 214
Score = 116 bits (278), Expect = 3e-25
Identities = 65/213 (30%), Positives = 100/213 (46%), Gaps = 20/213 (9%)
Query: 268 YEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYC 327
YE E ++ EC N + +V L C P + GE C +D C
Sbjct: 57 YEQSEHNVCQDIDECTAGTHNCRADQVCINLR-GSFACQCPPGYQKRGEQCV---DIDEC 112
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCV 385
+ C + C+N + C+C+ GFQ + TC D++EC + + C +C
Sbjct: 113 TIPPYCHQR--CVNTPGSFYCQCSPGFQLAANNYTCVDINECDAS-----NQCAQ--QCY 163
Query: 386 NVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE-G 443
N++G ++CQC GY D+ NC ++DEC +++ C C N PG ++C C GY+
Sbjct: 164 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ--CVNEPGKFSCMCPQGYQVV 221
Query: 444 DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
TC ++EC E ++ C C N GGFRC
Sbjct: 222 RSRTCQDINEC-ETTNECREDEMCWNYHGGFRC 253
Score = 92.3 bits (219), Expect = 5e-18
Identities = 38/85 (44%), Positives = 49/85 (57%), Gaps = 3/85 (3%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
QC GY + + C ++DEC TH C AD VC N GS+ C+C GY+ G C+ +DE
Sbjct: 52 QCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDE 111
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
CT + CH RCVN G F C+C
Sbjct: 112 CTIPPY-CHQ--RCVNTPGSFYCQC 133
Score = 78.6 bits (185), Expect = 6e-14
Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 15/127 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C ++ C+ + C + C N+ + C+CNQG++ D L C+D+DEC+ + L C
Sbjct: 146 CVDINECDASNQCAQQ--CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYL----C 199
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC--- 435
+CVN G + C C GY C +++ECE T+ C D +C N G + C
Sbjct: 200 QY--QCVNEPGKFSCMCPQGYQVVRSRTCQDINECE-TTNECREDEMCWNYHGGFRCYPR 256
Query: 436 -RCRDGY 441
C+D Y
Sbjct: 257 NPCQDPY 263
>BC098561-1|AAH98561.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 117 bits (282), Expect = 1e-25
Identities = 58/162 (35%), Positives = 82/162 (50%), Gaps = 16/162 (9%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C G H+C + C+NL + C+C G+Q G C D+DEC +CH
Sbjct: 171 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIP-----PYCH 225
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN G + CQC G+ + + CV+++EC+ + C C N GS+ C+C
Sbjct: 226 Q--RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQ--CYNILGSFICQCN 280
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE D C +DEC S+ C + +CVN G F C C
Sbjct: 281 QGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEPGKFSCMC 320
Score = 116 bits (278), Expect = 3e-25
Identities = 65/213 (30%), Positives = 100/213 (46%), Gaps = 20/213 (9%)
Query: 268 YEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYC 327
YE E ++ EC N + +V L C P + GE C +D C
Sbjct: 163 YEQSEHNVCQDIDECTAGTHNCRADQVCINLR-GSFACQCPPGYQKRGEQCV---DIDEC 218
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCV 385
+ C + C+N + C+C+ GFQ + TC D++EC + + C +C
Sbjct: 219 TIPPYCHQR--CVNTPGSFYCQCSPGFQLAANNYTCVDINECDAS-----NQCAQ--QCY 269
Query: 386 NVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE-G 443
N++G ++CQC GY D+ NC ++DEC +++ C C N PG ++C C GY+
Sbjct: 270 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ--CVNEPGKFSCMCPQGYQVV 327
Query: 444 DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
TC ++EC E ++ C C N GGFRC
Sbjct: 328 RSRTCQDINEC-ETTNECREDEMCWNYHGGFRC 359
Score = 92.3 bits (219), Expect = 5e-18
Identities = 38/85 (44%), Positives = 49/85 (57%), Gaps = 3/85 (3%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
QC GY + + C ++DEC TH C AD VC N GS+ C+C GY+ G C+ +DE
Sbjct: 158 QCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDE 217
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
CT + CH RCVN G F C+C
Sbjct: 218 CTIPPY-CHQ--RCVNTPGSFYCQC 239
Score = 78.6 bits (185), Expect = 6e-14
Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 15/127 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C ++ C+ + C + C N+ + C+CNQG++ D L C+D+DEC+ + L C
Sbjct: 252 CVDINECDASNQCAQQ--CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYL----C 305
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC--- 435
+CVN G + C C GY C +++ECE T+ C D +C N G + C
Sbjct: 306 QY--QCVNEPGKFSCMCPQGYQVVRSRTCQDINECE-TTNECREDEMCWNYHGGFRCYPR 362
Query: 436 -RCRDGY 441
C+D Y
Sbjct: 363 NPCQDPY 369
Score = 38.3 bits (85), Expect = 0.084
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 432 SYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+YT +C DGYE D C +DEC C +CVN GG+ C
Sbjct: 25 TYT-QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 36.3 bits (80), Expect = 0.34
Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 7/50 (14%)
Query: 346 YTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
YT +C G++ D + C+D+DEC + C +CVN GGY+C
Sbjct: 26 YT-QCTDGYEWDPVRQQCKDIDECD----IVPDACKGGMKCVNHYGGYLC 70
>BC014410-1|AAH14410.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 117 bits (282), Expect = 1e-25
Identities = 58/162 (35%), Positives = 82/162 (50%), Gaps = 16/162 (9%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C G H+C + C+NL + C+C G+Q G C D+DEC +CH
Sbjct: 171 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIP-----PYCH 225
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN G + CQC G+ + + CV+++EC+ + C C N GS+ C+C
Sbjct: 226 Q--RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQ--CYNILGSFICQCN 280
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE D C +DEC S+ C + +CVN G F C C
Sbjct: 281 QGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEPGKFSCMC 320
Score = 116 bits (278), Expect = 3e-25
Identities = 65/213 (30%), Positives = 100/213 (46%), Gaps = 20/213 (9%)
Query: 268 YEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYC 327
YE E ++ EC N + +V L C P + GE C +D C
Sbjct: 163 YEQSEHNVCQDIDECTAGTHNCRADQVCINLR-GSFACQCPPGYQKRGEQCV---DIDEC 218
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCV 385
+ C + C+N + C+C+ GFQ + TC D++EC + + C +C
Sbjct: 219 TIPPYCHQR--CVNTPGSFYCQCSPGFQLAANNYTCVDINECDAS-----NQCAQ--QCY 269
Query: 386 NVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE-G 443
N++G ++CQC GY D+ NC ++DEC +++ C C N PG ++C C GY+
Sbjct: 270 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ--CVNEPGKFSCMCPQGYQVV 327
Query: 444 DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
TC ++EC E ++ C C N GGFRC
Sbjct: 328 RSRTCQDINEC-ETTNECREDEMCWNYHGGFRC 359
Score = 92.3 bits (219), Expect = 5e-18
Identities = 38/85 (44%), Positives = 49/85 (57%), Gaps = 3/85 (3%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
QC GY + + C ++DEC TH C AD VC N GS+ C+C GY+ G C+ +DE
Sbjct: 158 QCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDE 217
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
CT + CH RCVN G F C+C
Sbjct: 218 CTIPPY-CHQ--RCVNTPGSFYCQC 239
Score = 78.6 bits (185), Expect = 6e-14
Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 15/127 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C ++ C+ + C + C N+ + C+CNQG++ D L C+D+DEC+ + L C
Sbjct: 252 CVDINECDASNQCAQQ--CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYL----C 305
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC--- 435
+CVN G + C C GY C +++ECE T+ C D +C N G + C
Sbjct: 306 QY--QCVNEPGKFSCMCPQGYQVVRSRTCQDINECE-TTNECREDEMCWNYHGGFRCYPR 362
Query: 436 -RCRDGY 441
C+D Y
Sbjct: 363 NPCQDPY 369
Score = 38.3 bits (85), Expect = 0.084
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 432 SYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+YT +C DGYE D C +DEC C +CVN GG+ C
Sbjct: 25 TYT-QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 36.3 bits (80), Expect = 0.34
Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 7/50 (14%)
Query: 346 YTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
YT +C G++ D + C+D+DEC + C +CVN GGY+C
Sbjct: 26 YT-QCTDGYEWDPVRQQCKDIDECD----IVPDACKGGMKCVNHYGGYLC 70
>AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein.
Length = 1231
Score = 117 bits (282), Expect = 1e-25
Identities = 70/201 (34%), Positives = 91/201 (45%), Gaps = 18/201 (8%)
Query: 284 CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNL 342
C G C C R P + + + K C V+ C G H C E C NL
Sbjct: 868 CRPG-FSCINTVGSYTCQRNPLICARGYHASDDGXK-CVDVNECETGVHRCGEGQVCHNL 925
Query: 343 NTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
Y C C GFQ D G C DV+EC + G H C N +G Y C C G+
Sbjct: 926 PGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT-----CENTLGSYRCSCASGFL 980
Query: 401 -RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEG 457
D C +V+ECE C + C N GSY C CR GY+ DG+TC +DEC +G
Sbjct: 981 LAADGKRCEDVNECEAQR--CSQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQG 1036
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
+ + RC+N+ G ++C C
Sbjct: 1037 AGILC-TFRCLNVPGSYQCAC 1056
Score = 111 bits (267), Expect = 7e-24
Identities = 63/173 (36%), Positives = 78/173 (45%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTC----KCNQGFQGDGL-TCQDVDECQEAGGLH 374
C VD C MG H+C C N + C +C GF D C D++EC
Sbjct: 809 CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLS--- 865
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTN 428
C C+N VG Y CQ C GY D CV+V+ECE H C VC N
Sbjct: 866 -EPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGXKCVDVNECETGVHRCGEGQVCHN 924
Query: 429 TPGSYTCRCRDGYEGD--GYTCMHVDEC-TEGSHTCHHSARCVNIDGGFRCEC 478
PGSY C C+ G++ D G C+ V+EC C H+ C N G +RC C
Sbjct: 925 LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHT--CENTLGSYRCSC 975
Score = 107 bits (258), Expect = 9e-23
Identities = 61/164 (37%), Positives = 76/164 (46%), Gaps = 19/164 (11%)
Query: 321 CPGVDYC--NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
C V+ C + G C TC N Y C C GF DG C+DV+EC+
Sbjct: 946 CIDVNECWASPGRLCQH--TCENTLGSYRCSCASGFLLAADGKRCEDVNECE------AQ 997
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C + C N+ G Y C C GY +D C ++DEC G C N PGSY C
Sbjct: 998 RC--SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGA-GILCTFRCLNVPGSYQC 1054
Query: 436 RCRD-GYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C + GY +G +C VDEC G+H C + C NI G FRC
Sbjct: 1055 ACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1098
Score = 97.5 bits (232), Expect = 1e-19
Identities = 53/167 (31%), Positives = 70/167 (41%), Gaps = 17/167 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCH 379
P + C C + C + C C G+ DG++C+D DEC + H C
Sbjct: 678 PQPNTCKDNGPCKQ--VCSTVGGSAICSCFPGYAIMADGVSCEDQDECL----MGAHDCS 731
Query: 380 SNTRCVNVVGGYVCQ-----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
CVN +G + C C GY CV+++EC + H C C NT GS+
Sbjct: 732 RRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFH 791
Query: 435 C----RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCE 477
C C GY C VDEC G+HTC C N G F C+
Sbjct: 792 CYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQ 838
Score = 58.8 bits (136), Expect = 6e-08
Identities = 67/267 (25%), Positives = 102/267 (38%), Gaps = 36/267 (13%)
Query: 177 HIHDLSLKLVGAEARISRLEQCDCQKSCYS-NGTVHAD-GATWQRDCNRCSCVH-GEITC 233
H D K V + + +C + C++ G+ D A +QRD C+ E
Sbjct: 895 HASDDGXKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWA 954
Query: 234 RPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTR 293
P + C+N + G +C LL + G+R ++ EC + +C
Sbjct: 955 SPGRLCQHTCENTL---GSYRCSCASGFLLAAD----GKRC--EDVNECEAQRCSQECAN 1005
Query: 294 VDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKC-NQ 352
+ C C Q + G C +D C G C+N+ Y C C Q
Sbjct: 1006 IYGSYQCY---CRQGYQLAEDGHTCT---DIDECAQGAGILCTFRCLNVPGSYQCACPEQ 1059
Query: 353 GFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC---QCLGGYTRKDKFNC 407
G+ +G +C+DVDEC L H+C C N+ G + C +C Y + K
Sbjct: 1060 GYTMTANGRSCKDVDEC----ALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSK--- 1112
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYT 434
+CE T CH C N+P T
Sbjct: 1113 ---TKCERTT--CHDFLECQNSPARIT 1134
Score = 51.2 bits (117), Expect = 1e-05
Identities = 25/61 (40%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 425 VCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTEN 482
VC+ GS C C GY DG +C DEC G+H C CVN G F C T
Sbjct: 692 VCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVL 751
Query: 483 C 483
C
Sbjct: 752 C 752
Score = 35.5 bits (78), Expect = 0.60
Identities = 40/151 (26%), Positives = 54/151 (35%), Gaps = 22/151 (14%)
Query: 233 CRPVECDRAE-CKNPVLHPGECCPTCLRQ-----------CL----LWGNLYEHGERFAP 276
C VEC E C L PG CC TC++Q CL + G + F
Sbjct: 33 CTGVECPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCLQGGFVRGRVPAGQSYFVD 92
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
EC C G + + + CP LP + + V + C C V + GH
Sbjct: 93 FGSTECSCPPGGGKIS--CQFMLCPELPPNCIEAV-VVADSCPQCGQVGCVHAGHXYAAG 149
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDEC 367
T ++L C C G L C + C
Sbjct: 150 HT-VHLPPCRACHCPDA--GGELICYQLPGC 177
>AY004330-1|AAK11491.1| 493|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 protein.
Length = 493
Score = 117 bits (282), Expect = 1e-25
Identities = 58/162 (35%), Positives = 82/162 (50%), Gaps = 16/162 (9%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C G H+C + C+NL + C+C G+Q G C D+DEC +CH
Sbjct: 171 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIP-----PYCH 225
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN G + CQC G+ + + CV+++EC+ + C C N GS+ C+C
Sbjct: 226 Q--RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQ--CYNILGSFICQCN 280
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE D C +DEC S+ C + +CVN G F C C
Sbjct: 281 QGYELSSDRLNCEDIDECRTSSYLCQY--QCVNEPGKFSCMC 320
Score = 116 bits (278), Expect = 3e-25
Identities = 65/213 (30%), Positives = 100/213 (46%), Gaps = 20/213 (9%)
Query: 268 YEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYC 327
YE E ++ EC N + +V L C P + GE C +D C
Sbjct: 163 YEQSEHNVCQDIDECTAGTHNCRADQVCINLR-GSFACQCPPGYQKRGEQCV---DIDEC 218
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCV 385
+ C + C+N + C+C+ GFQ + TC D++EC + + C +C
Sbjct: 219 TIPPYCHQR--CVNTPGSFYCQCSPGFQLAANNYTCVDINECDAS-----NQCAQ--QCY 269
Query: 386 NVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE-G 443
N++G ++CQC GY D+ NC ++DEC +++ C C N PG ++C C GY+
Sbjct: 270 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ--CVNEPGKFSCMCPQGYQVV 327
Query: 444 DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
TC ++EC E ++ C C N GGFRC
Sbjct: 328 RSRTCQDINEC-ETTNECREDEMCWNYHGGFRC 359
Score = 92.3 bits (219), Expect = 5e-18
Identities = 38/85 (44%), Positives = 49/85 (57%), Gaps = 3/85 (3%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
QC GY + + C ++DEC TH C AD VC N GS+ C+C GY+ G C+ +DE
Sbjct: 158 QCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDE 217
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
CT + CH RCVN G F C+C
Sbjct: 218 CTIPPY-CHQ--RCVNTPGSFYCQC 239
Score = 78.6 bits (185), Expect = 6e-14
Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 15/127 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C ++ C+ + C + C N+ + C+CNQG++ D L C+D+DEC+ + L C
Sbjct: 252 CVDINECDASNQCAQQ--CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYL----C 305
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC--- 435
+CVN G + C C GY C +++ECE T+ C D +C N G + C
Sbjct: 306 QY--QCVNEPGKFSCMCPQGYQVVRSRTCQDINECE-TTNECREDEMCWNYHGGFRCYPR 362
Query: 436 -RCRDGY 441
C+D Y
Sbjct: 363 NPCQDPY 369
Score = 38.3 bits (85), Expect = 0.084
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 432 SYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+YT +C DGYE D C +DEC C +CVN GG+ C
Sbjct: 25 TYT-QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 36.3 bits (80), Expect = 0.34
Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 7/50 (14%)
Query: 346 YTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
YT +C G++ D + C+D+DEC + C +CVN GGY+C
Sbjct: 26 YT-QCTDGYEWDPVRQQCKDIDECD----IVPDACKGGMKCVNHYGGYLC 70
>AB209212-1|BAD92449.1| 418|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 1 isoform b
variant protein.
Length = 418
Score = 117 bits (282), Expect = 1e-25
Identities = 58/162 (35%), Positives = 82/162 (50%), Gaps = 16/162 (9%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C G H+C + C+NL + C+C G+Q G C D+DEC +CH
Sbjct: 96 CQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIP-----PYCH 150
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN G + CQC G+ + + CV+++EC+ + C C N GS+ C+C
Sbjct: 151 Q--RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQ--CYNILGSFICQCN 205
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE D C +DEC S+ C + +CVN G F C C
Sbjct: 206 QGYELSSDRLNCEDIDECRTSSYLCQY--QCVNQPGKFSCMC 245
Score = 116 bits (278), Expect = 3e-25
Identities = 65/213 (30%), Positives = 100/213 (46%), Gaps = 20/213 (9%)
Query: 268 YEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYC 327
YE E ++ EC N + +V L C P + GE C +D C
Sbjct: 88 YEQSEHNVCQDIDECTAGTHNCRADQVCINLR-GSFACQCPPGYQKRGEQCV---DIDEC 143
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCV 385
+ C + C+N + C+C+ GFQ + TC D++EC + + C +C
Sbjct: 144 TIPPYCHQR--CVNTPGSFYCQCSPGFQLAANNYTCVDINECDAS-----NQCAQ--QCY 194
Query: 386 NVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE-G 443
N++G ++CQC GY D+ NC ++DEC +++ C C N PG ++C C GY+
Sbjct: 195 NILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ--CVNQPGKFSCMCPQGYQVV 252
Query: 444 DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
TC ++EC E ++ C C N GGFRC
Sbjct: 253 RSRTCQDINEC-ETTNECREDEMCWNYHGGFRC 284
Score = 92.3 bits (219), Expect = 5e-18
Identities = 38/85 (44%), Positives = 49/85 (57%), Gaps = 3/85 (3%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
QC GY + + C ++DEC TH C AD VC N GS+ C+C GY+ G C+ +DE
Sbjct: 83 QCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDE 142
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
CT + CH RCVN G F C+C
Sbjct: 143 CTIPPY-CHQ--RCVNTPGSFYCQC 164
Score = 78.6 bits (185), Expect = 6e-14
Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 15/127 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C ++ C+ + C + C N+ + C+CNQG++ D L C+D+DEC+ + L C
Sbjct: 177 CVDINECDASNQCAQQ--CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYL----C 230
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC--- 435
+CVN G + C C GY C +++ECE T+ C D +C N G + C
Sbjct: 231 QY--QCVNQPGKFSCMCPQGYQVVRSRTCQDINECE-TTNECREDEMCWNYHGGFRCYPR 287
Query: 436 -RCRDGY 441
C+D Y
Sbjct: 288 NPCQDPY 294
>BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein.
Length = 715
Score = 117 bits (281), Expect = 2e-25
Identities = 58/153 (37%), Positives = 75/153 (49%), Gaps = 17/153 (11%)
Query: 331 HSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
H+C C+N+ Y C+C QG+ D TC+ D C + H+C CVNV
Sbjct: 6 HNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLC----AMEDHNCEQ--LCVNVP 57
Query: 389 GGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDG 445
G +VCQC GY +D CV VD C HGC + C N GSY C+C +G+ D
Sbjct: 58 GSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHE--CVNADGSYLCQCHEGFALNPDE 115
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
TC +D C +H C H CVN D + C C
Sbjct: 116 KTCTKIDYCASSNHGCQH--ECVNTDDSYSCHC 146
Score = 112 bits (269), Expect = 4e-24
Identities = 62/180 (34%), Positives = 87/180 (48%), Gaps = 19/180 (10%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQG--FQGDGLTC 361
C + F + E K C VDYC + H C+ + C+N++ + C+C +G + DG TC
Sbjct: 226 CQCSEGFLI-NEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTC 282
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGC 420
+D C L H C + CV+ +VCQC GY R+D C D C+ HGC
Sbjct: 283 AKLDSC----ALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGC 336
Query: 421 HADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +C N+ SYTC C +G+ DG C D C H C H CVN + C+C
Sbjct: 337 --EHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHI--CVNNGNSYICKC 392
Score = 111 bits (266), Expect = 1e-23
Identities = 60/166 (36%), Positives = 79/166 (47%), Gaps = 18/166 (10%)
Query: 319 KFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHG 375
K C VDYC + H C+ C+N + Y C+C++GF D TC +D C +
Sbjct: 75 KRCVAVDYCASENHGCEHE--CVNADGSYLCQCHEGFALNPDEKTCTKIDYCASSN---- 128
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
H C CVN Y C CL G+T DK C ++ C N GC + C N SY
Sbjct: 129 HGCQHE--CVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHE--CVNMEESYY 184
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CRC GY + +G TC VD C + H C C+N + F C+C
Sbjct: 185 CRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQC 228
Score = 110 bits (265), Expect = 1e-23
Identities = 58/166 (34%), Positives = 82/166 (49%), Gaps = 16/166 (9%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C ++YC + E+ C+N+ Y C+C++G+ D G TC VD C + H
Sbjct: 157 KTCRRINYCALNKPGCEHE-CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQ----QDH 211
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N +VCQC G+ +D C VD C + HGC C N S+ C
Sbjct: 212 GCEQ--LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFAC 267
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+C +G+ DG TC +D C G H C HS CV+ + F C+CF
Sbjct: 268 QCPEGHVLRSDGKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCF 311
Score = 86.2 bits (204), Expect = 3e-16
Identities = 56/179 (31%), Positives = 79/179 (44%), Gaps = 25/179 (13%)
Query: 285 HDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLN 343
H C +D AC C G K C +D C +G H C+ + C++
Sbjct: 252 HGCEYSCVNMDRSFACQ---CPEGHVLRSDG---KTCAKLDSCALGDHGCEHS--CVSSE 303
Query: 344 TKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT- 400
+ C+C +G+ + DG TC+ D CQ H C CVN Y C+CL G+
Sbjct: 304 DSFVCQCFEGYILREDGKTCRRKDVCQAID----HGCEHI--CVNSDDSYTCECLEGFRL 357
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
+D C D C+ HGC + +C N SY C+C +G+ DG C +CTEG
Sbjct: 358 AEDGKRCRRKDVCKSTHHGC--EHICVNNGNSYICKCSEGFVLAEDGRRC---KKCTEG 411
Score = 59.7 bits (138), Expect = 3e-08
Identities = 28/70 (40%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNI 470
C H C C N PGSY CRC+ GY D TC D C H C CVN+
Sbjct: 1 CSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNV 56
Query: 471 DGGFRCECFT 480
G F C+C++
Sbjct: 57 PGSFVCQCYS 66
Score = 38.3 bits (85), Expect = 0.084
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 9/109 (8%)
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
QC L E G+ K+ + + H C D C L + F + E K
Sbjct: 309 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECL-----EGFRL-AEDGK 362
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDE 366
C D C H E+ C+N Y CKC++GF DG C+ E
Sbjct: 363 RCRRKDVCKSTHHGCEHI-CVNNGNSYICKCSEGFVLAEDGRRCKKCTE 410
>M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein.
Length = 1394
Score = 116 bits (280), Expect = 2e-25
Identities = 68/201 (33%), Positives = 93/201 (46%), Gaps = 17/201 (8%)
Query: 290 QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK 349
QC + C CD + S G+ C+ ++ C S + C+N Y C
Sbjct: 807 QCRNTEGSFQCV---CDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYDCT 860
Query: 350 CNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNC 407
C GFQ D TCQD++EC+ G C C+N G + C C G++ D C
Sbjct: 861 CPDGFQLDDNKTCQDINECEHPG-----LCGPQGECLNTEGSFHCVCQQGFSISADGRTC 915
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMHVDECTEGSHTCHHSA 465
++DEC NT C + C NT GS+ C C G++ DG C+ V+EC S C A
Sbjct: 916 EDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC-GEA 973
Query: 466 RCVNIDGGFRCECFTENCELS 486
C N++G F C C EN E S
Sbjct: 974 FCENVEGSFLCVCADENQEYS 994
Score = 114 bits (274), Expect = 1e-24
Identities = 66/212 (31%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 277 KECAEC-VCHDGNM----QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGH 331
K C + C GN+ QC + C C Q S + C+ +D C H
Sbjct: 748 KHCRDIDECQQGNLCVNGQCKNTEGSFRCT---CGQGYQLSAAKDQCE---DIDECQHRH 801
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVG 389
C + C N + C C+QG++ GL C+D++EC E + C C+N G
Sbjct: 802 LC-AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV----CQRGD-CINTAG 855
Query: 390 GYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYT 447
Y C C G+ D C +++ECE + C C NT GS+ C C+ G+ DG T
Sbjct: 856 SYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 914
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC + C C N G FRC C+
Sbjct: 915 CEDIDECVNNT-VCDSHGFCDNTAGSFRCLCY 945
Score = 103 bits (248), Expect = 2e-21
Identities = 61/163 (37%), Positives = 83/163 (50%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C +C + C+N Y C C +GF+G C DVDEC L + C
Sbjct: 669 CEDIDECLNPSTCPDEQ-CVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-----LEPNVC- 721
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
+N C N+ G Y+C C GYTR D +C ++DEC +GN C + C NT GS+ C C
Sbjct: 722 ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNL--C-VNGQCKNTEGSFRCTC 778
Query: 438 RDGYEGDGY--TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY+ C +DEC + H C H +C N +G F+C C
Sbjct: 779 GQGYQLSAAKDQCEDIDEC-QHRHLCAH-GQCRNTEGSFQCVC 819
Score = 99.1 bits (236), Expect = 4e-20
Identities = 58/163 (35%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHH 377
C +D C + H C + C N + C C GF +G C DVDEC L
Sbjct: 586 CVDIDECTQVQHLCSQGR-CENTEGSFLCICPAGFMASEEGTNCIDVDEC-----LRPDV 639
Query: 378 CHSNTRCVNVVGGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC- 435
C CVN VG + C+ C GY + C ++DEC N C D C N+PGSY C
Sbjct: 640 C-GEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECL-NPSTC-PDEQCVNSPGSYQCV 696
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +G+ G C+ VDEC E + C + C N++G + C C
Sbjct: 697 PCTEGFRGWNGQCLDVDECLE-PNVC-ANGDCSNLEGSYMCSC 737
Score = 88.2 bits (209), Expect = 8e-17
Identities = 58/173 (33%), Positives = 78/173 (45%), Gaps = 24/173 (13%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C GH C+NL +YTC C +G F C D+DEC + H S
Sbjct: 555 DICGAGH-------CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQV-----QHLCSQG 602
Query: 383 RCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-CRDG 440
RC N G ++C C G+ ++ NC++VDEC C + C NT G++ C C G
Sbjct: 603 RCENTEGSFLCICPAGFMASEEGTNCIDVDECL-RPDVC-GEGHCVNTVGAFRCEYCDSG 660
Query: 441 YE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGR 492
Y C +DEC S TC +CVN G ++C TE W G+
Sbjct: 661 YRMTQRGRCEDIDECLNPS-TC-PDEQCVNSPGSYQCVPCTEGFR---GWNGQ 708
Score = 61.7 bits (143), Expect = 8e-09
Identities = 34/79 (43%), Positives = 41/79 (51%), Gaps = 6/79 (7%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECE--GNTHGCHA 422
+ +E G L+G C N RCV V GY C CL GY K C +V+EC+ N
Sbjct: 1294 QAEECGILNG--CE-NGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSLCK 1350
Query: 423 DAVCTNTPGSYTCRCRDGY 441
+A C NT GSY C C GY
Sbjct: 1351 NAKCINTDGSYKCLCLPGY 1369
Score = 61.7 bits (143), Expect = 8e-09
Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRC 384
C + + C EN C+ + YTC C G+ D +TC DV+EC E C N +C
Sbjct: 1298 CGILNGC-ENGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNRMSL-C-KNAKC 1354
Query: 385 VNVVGGYVCQCLGGYTRKDKFN 406
+N G Y C CL GY DK N
Sbjct: 1355 INTDGSYKCLCLPGYVPSDKPN 1376
Score = 58.8 bits (136), Expect = 6e-08
Identities = 55/200 (27%), Positives = 82/200 (41%), Gaps = 38/200 (19%)
Query: 222 NRCSCVHGEITCRPVE------CDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
+R C HG+ CR E CD+ + + G+ C + +CL ++ + G+
Sbjct: 799 HRHLCAHGQ--CRNTEGSFQCVCDQGYRASGL---GDHCED-INECLEDKSVCQRGDCIN 852
Query: 276 PKECAECVCHDG-----NMQCTRVD----PELACPR---------LPCDPPQQFSVPGEC 317
+C C DG N C ++ P L P+ C Q FS+ +
Sbjct: 853 TAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 912
Query: 318 CKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHG 375
+ C +D C CD + C N + C C QGFQ DG C DV+EC+ G+ G
Sbjct: 913 -RTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 971
Query: 376 HHCHSNTRCVNVVGGYVCQC 395
C NV G ++C C
Sbjct: 972 -----EAFCENVEGSFLCVC 986
Score = 54.8 bits (126), Expect = 9e-07
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Query: 403 DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCMHVDECTEGSHT 460
+ F ++ +EC G +GC + C YTC C DGY D TC V+EC E ++
Sbjct: 1288 NSFEELQAEEC-GILNGCE-NGRCVRVQEGYTCDCLDGYHLDTAKMTCFDVNECDELNNR 1345
Query: 461 CH--HSARCVNIDGGFRCEC 478
+A+C+N DG ++C C
Sbjct: 1346 MSLCKNAKCINTDGSYKCLC 1365
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 355 QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDEC 413
+ G +D DEC L G N C+N GY C C G Y K C ++DEC
Sbjct: 1089 EAGGENYKDADECL----LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC 1144
Query: 414 EGNTHGCHADAVCTNTPGSYTCRC 437
+ + C D C NT GSY C C
Sbjct: 1145 Q-DPSSC-IDGQCVNTEGSYNCFC 1166
Score = 47.6 bits (108), Expect = 1e-04
Identities = 56/201 (27%), Positives = 75/201 (37%), Gaps = 22/201 (10%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS--CDENATC 339
CVC D N + + + + R D P E K C Y N+ + CD N
Sbjct: 984 CVCADENQEYSPMTGQCRS-RTSTDLDVDVDQPKEEKKEC----YYNLNDASLCD-NVLA 1037
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY 399
N+ TK C C G G G C+ + C G + V G GG
Sbjct: 1038 PNV-TKQECCCTSG-AGWGDNCE-IFPCPVLGTAEFTEMCPKGKGF-VPAGESSSEAGGE 1093
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEG 457
KD DEC + C NT Y C C+ G Y+ C +DEC +
Sbjct: 1094 NYKD------ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDP 1147
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S +C +CVN +G + C C
Sbjct: 1148 S-SC-IDGQCVNTEGSYNCFC 1166
Score = 44.0 bits (99), Expect = 0.002
Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+CL GY R + C +++EC+ G + C NT GSY C C+ G+ D
Sbjct: 285 ECLPGYKRVNNTFCQDINECQ--LQGVCPNGECLNTMGSYRCTCKIGFGPD 333
Score = 34.3 bits (75), Expect = 1.4
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 8/62 (12%)
Query: 349 KCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-N 406
+C G++ T CQD++ECQ G C N C+N +G Y C C G+ F +
Sbjct: 285 ECLPGYKRVNNTFCQDINECQLQGV-----C-PNGECLNTMGSYRCTCKIGFGPDPTFSS 338
Query: 407 CV 408
CV
Sbjct: 339 CV 340
Score = 31.5 bits (68), Expect = 9.7
Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
FC ++ C + C N C+N Y C C GF D
Sbjct: 297 FCQDINECQLQGVCP-NGECLNTMGSYRCTCKIGFGPD 333
>BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming growth
factor beta binding protein 1 protein.
Length = 1395
Score = 116 bits (280), Expect = 2e-25
Identities = 68/201 (33%), Positives = 93/201 (46%), Gaps = 17/201 (8%)
Query: 290 QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK 349
QC + C CD + S G+ C+ ++ C S + C+N Y C
Sbjct: 808 QCRNTEGSFQCV---CDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYDCT 861
Query: 350 CNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNC 407
C GFQ D TCQD++EC+ G C C+N G + C C G++ D C
Sbjct: 862 CPDGFQLDDNKTCQDINECEHPG-----LCGPQGECLNTEGSFHCVCQQGFSISADGRTC 916
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMHVDECTEGSHTCHHSA 465
++DEC NT C + C NT GS+ C C G++ DG C+ V+EC S C A
Sbjct: 917 EDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC-GEA 974
Query: 466 RCVNIDGGFRCECFTENCELS 486
C N++G F C C EN E S
Sbjct: 975 FCENVEGSFLCVCADENQEYS 995
Score = 114 bits (274), Expect = 1e-24
Identities = 66/212 (31%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 277 KECAEC-VCHDGNM----QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGH 331
K C + C GN+ QC + C C Q S + C+ +D C H
Sbjct: 749 KHCRDIDECQQGNLCVNGQCKNTEGSFRCT---CGQGYQLSAAKDQCE---DIDECQHRH 802
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVG 389
C + C N + C C+QG++ GL C+D++EC E + C C+N G
Sbjct: 803 LC-AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV----CQRGD-CINTAG 856
Query: 390 GYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYT 447
Y C C G+ D C +++ECE + C C NT GS+ C C+ G+ DG T
Sbjct: 857 SYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 915
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC + C C N G FRC C+
Sbjct: 916 CEDIDECVNNT-VCDSHGFCDNTAGSFRCLCY 946
Score = 103 bits (248), Expect = 2e-21
Identities = 61/163 (37%), Positives = 83/163 (50%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C +C + C+N Y C C +GF+G C DVDEC L + C
Sbjct: 670 CEDIDECLNPSTCPDEQ-CVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-----LEPNVC- 722
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
+N C N+ G Y+C C GYTR D +C ++DEC +GN C + C NT GS+ C C
Sbjct: 723 ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNL--C-VNGQCKNTEGSFRCTC 779
Query: 438 RDGYEGDGY--TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY+ C +DEC + H C H +C N +G F+C C
Sbjct: 780 GQGYQLSAAKDQCEDIDEC-QHRHLCAH-GQCRNTEGSFQCVC 820
Score = 99.1 bits (236), Expect = 4e-20
Identities = 58/163 (35%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHH 377
C +D C + H C + C N + C C GF +G C DVDEC L
Sbjct: 587 CVDIDECTQVQHLCSQGR-CENTEGSFLCICPAGFMASEEGTNCIDVDEC-----LRPDV 640
Query: 378 CHSNTRCVNVVGGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC- 435
C CVN VG + C+ C GY + C ++DEC N C D C N+PGSY C
Sbjct: 641 C-GEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECL-NPSTC-PDEQCVNSPGSYQCV 697
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +G+ G C+ VDEC E + C + C N++G + C C
Sbjct: 698 PCTEGFRGWNGQCLDVDECLE-PNVC-ANGDCSNLEGSYMCSC 738
Score = 88.2 bits (209), Expect = 8e-17
Identities = 58/173 (33%), Positives = 78/173 (45%), Gaps = 24/173 (13%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C GH C+NL +YTC C +G F C D+DEC + H S
Sbjct: 556 DICGAGH-------CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQV-----QHLCSQG 603
Query: 383 RCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-CRDG 440
RC N G ++C C G+ ++ NC++VDEC C + C NT G++ C C G
Sbjct: 604 RCENTEGSFLCICPAGFMASEEGTNCIDVDECL-RPDVC-GEGHCVNTVGAFRCEYCDSG 661
Query: 441 YE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGR 492
Y C +DEC S TC +CVN G ++C TE W G+
Sbjct: 662 YRMTQRGRCEDIDECLNPS-TC-PDEQCVNSPGSYQCVPCTEGFR---GWNGQ 709
Score = 62.1 bits (144), Expect = 6e-09
Identities = 34/79 (43%), Positives = 41/79 (51%), Gaps = 6/79 (7%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECE--GNTHGCHA 422
+ +E G L+G C N RCV V GY C C GY K CV+V+EC+ N
Sbjct: 1295 QAEECGILNG--CE-NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCK 1351
Query: 423 DAVCTNTPGSYTCRCRDGY 441
+A C NT GSY C C GY
Sbjct: 1352 NAKCINTDGSYKCLCLPGY 1370
Score = 62.1 bits (144), Expect = 6e-09
Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRC 384
C + + C EN C+ + YTC C G+ D +TC DV+EC E C N +C
Sbjct: 1299 CGILNGC-ENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSL-C-KNAKC 1355
Query: 385 VNVVGGYVCQCLGGYTRKDKFN 406
+N G Y C CL GY DK N
Sbjct: 1356 INTDGSYKCLCLPGYVPSDKPN 1377
Score = 58.8 bits (136), Expect = 6e-08
Identities = 55/200 (27%), Positives = 82/200 (41%), Gaps = 38/200 (19%)
Query: 222 NRCSCVHGEITCRPVE------CDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
+R C HG+ CR E CD+ + + G+ C + +CL ++ + G+
Sbjct: 800 HRHLCAHGQ--CRNTEGSFQCVCDQGYRASGL---GDHCED-INECLEDKSVCQRGDCIN 853
Query: 276 PKECAECVCHDG-----NMQCTRVD----PELACPR---------LPCDPPQQFSVPGEC 317
+C C DG N C ++ P L P+ C Q FS+ +
Sbjct: 854 TAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 913
Query: 318 CKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHG 375
+ C +D C CD + C N + C C QGFQ DG C DV+EC+ G+ G
Sbjct: 914 -RTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 972
Query: 376 HHCHSNTRCVNVVGGYVCQC 395
C NV G ++C C
Sbjct: 973 -----EAFCENVEGSFLCVC 987
Score = 54.8 bits (126), Expect = 9e-07
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Query: 403 DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCMHVDECTEGSHT 460
+ F ++ +EC G +GC + C YTC C DGY D TC+ V+EC E ++
Sbjct: 1289 NSFEELQAEEC-GILNGCE-NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNR 1346
Query: 461 CH--HSARCVNIDGGFRCEC 478
+A+C+N DG ++C C
Sbjct: 1347 MSLCKNAKCINTDGSYKCLC 1366
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 355 QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDEC 413
+ G +D DEC L G N C+N GY C C G Y K C ++DEC
Sbjct: 1090 EAGGENYKDADECL----LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC 1145
Query: 414 EGNTHGCHADAVCTNTPGSYTCRC 437
+ + C D C NT GSY C C
Sbjct: 1146 Q-DPSSC-IDGQCVNTEGSYNCFC 1167
Score = 47.6 bits (108), Expect = 1e-04
Identities = 56/201 (27%), Positives = 75/201 (37%), Gaps = 22/201 (10%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS--CDENATC 339
CVC D N + + + + R D P E K C Y N+ + CD N
Sbjct: 985 CVCADENQEYSPMTGQCRS-RTSTDLDVDVDQPKEEKKEC----YYNLNDASLCD-NVLA 1038
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY 399
N+ TK C C G G G C+ + C G + V G GG
Sbjct: 1039 PNV-TKQECCCTSG-AGWGDNCE-IFPCPVLGTAEFTEMCPKGKGF-VPAGESSSEAGGE 1094
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEG 457
KD DEC + C NT Y C C+ G Y+ C +DEC +
Sbjct: 1095 NYKD------ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDP 1148
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S +C +CVN +G + C C
Sbjct: 1149 S-SC-IDGQCVNTEGSYNCFC 1167
Score = 44.0 bits (99), Expect = 0.002
Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+CL GY R + C +++EC+ G + C NT GSY C C+ G+ D
Sbjct: 285 ECLPGYKRVNNTFCQDINECQ--LQGVCPNGECLNTMGSYRCTCKIGFGPD 333
Score = 34.3 bits (75), Expect = 1.4
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 8/62 (12%)
Query: 349 KCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-N 406
+C G++ T CQD++ECQ G C N C+N +G Y C C G+ F +
Sbjct: 285 ECLPGYKRVNNTFCQDINECQLQGV-----C-PNGECLNTMGSYRCTCKIGFGPDPTFSS 338
Query: 407 CV 408
CV
Sbjct: 339 CV 340
Score = 31.5 bits (68), Expect = 9.7
Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
FC ++ C + C N C+N Y C C GF D
Sbjct: 297 FCQDINECQLQGVCP-NGECLNTMGSYRCTCKIGFGPD 333
>AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth
factor-beta binding protein-1S protein.
Length = 1394
Score = 116 bits (280), Expect = 2e-25
Identities = 68/201 (33%), Positives = 93/201 (46%), Gaps = 17/201 (8%)
Query: 290 QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK 349
QC + C CD + S G+ C+ ++ C S + C+N Y C
Sbjct: 807 QCRNTEGSFQCV---CDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYDCT 860
Query: 350 CNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNC 407
C GFQ D TCQD++EC+ G C C+N G + C C G++ D C
Sbjct: 861 CPDGFQLDDNKTCQDINECEHPG-----LCGPQGECLNTEGSFHCVCQQGFSISADGRTC 915
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMHVDECTEGSHTCHHSA 465
++DEC NT C + C NT GS+ C C G++ DG C+ V+EC S C A
Sbjct: 916 EDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC-GEA 973
Query: 466 RCVNIDGGFRCECFTENCELS 486
C N++G F C C EN E S
Sbjct: 974 FCENVEGSFLCVCADENQEYS 994
Score = 114 bits (274), Expect = 1e-24
Identities = 66/212 (31%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 277 KECAEC-VCHDGNM----QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGH 331
K C + C GN+ QC + C C Q S + C+ +D C H
Sbjct: 748 KHCRDIDECQQGNLCVNGQCKNTEGSFRCT---CGQGYQLSAAKDQCE---DIDECQHRH 801
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVG 389
C + C N + C C+QG++ GL C+D++EC E + C C+N G
Sbjct: 802 LC-AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV----CQRGD-CINTAG 855
Query: 390 GYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYT 447
Y C C G+ D C +++ECE + C C NT GS+ C C+ G+ DG T
Sbjct: 856 SYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 914
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC + C C N G FRC C+
Sbjct: 915 CEDIDECVNNT-VCDSHGFCDNTAGSFRCLCY 945
Score = 103 bits (248), Expect = 2e-21
Identities = 61/163 (37%), Positives = 83/163 (50%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C +C + C+N Y C C +GF+G C DVDEC L + C
Sbjct: 669 CEDIDECLNPSTCPDEQ-CVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-----LEPNVC- 721
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
+N C N+ G Y+C C GYTR D +C ++DEC +GN C + C NT GS+ C C
Sbjct: 722 ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNL--C-VNGQCKNTEGSFRCTC 778
Query: 438 RDGYEGDGY--TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY+ C +DEC + H C H +C N +G F+C C
Sbjct: 779 GQGYQLSAAKDQCEDIDEC-QHRHLCAH-GQCRNTEGSFQCVC 819
Score = 99.1 bits (236), Expect = 4e-20
Identities = 58/163 (35%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHH 377
C +D C + H C + C N + C C GF +G C DVDEC L
Sbjct: 586 CVDIDECTQVQHLCSQGR-CENTEGSFLCICPAGFMASEEGTNCIDVDEC-----LRPDV 639
Query: 378 CHSNTRCVNVVGGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC- 435
C CVN VG + C+ C GY + C ++DEC N C D C N+PGSY C
Sbjct: 640 C-GEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECL-NPSTC-PDEQCVNSPGSYQCV 696
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +G+ G C+ VDEC E + C + C N++G + C C
Sbjct: 697 PCTEGFRGWNGQCLDVDECLE-PNVC-ANGDCSNLEGSYMCSC 737
Score = 88.2 bits (209), Expect = 8e-17
Identities = 58/173 (33%), Positives = 78/173 (45%), Gaps = 24/173 (13%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C GH C+NL +YTC C +G F C D+DEC + H S
Sbjct: 555 DICGAGH-------CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQV-----QHLCSQG 602
Query: 383 RCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-CRDG 440
RC N G ++C C G+ ++ NC++VDEC C + C NT G++ C C G
Sbjct: 603 RCENTEGSFLCICPAGFMASEEGTNCIDVDECL-RPDVC-GEGHCVNTVGAFRCEYCDSG 660
Query: 441 YE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGR 492
Y C +DEC S TC +CVN G ++C TE W G+
Sbjct: 661 YRMTQRGRCEDIDECLNPS-TC-PDEQCVNSPGSYQCVPCTEGFR---GWNGQ 708
Score = 63.7 bits (148), Expect = 2e-09
Identities = 35/79 (44%), Positives = 42/79 (53%), Gaps = 6/79 (7%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECE--GNTHGCHA 422
+ +E G L+G C N RCV V GY C CL GY K CV+V+EC+ N
Sbjct: 1294 QAEECGILNG--CE-NGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSLCK 1350
Query: 423 DAVCTNTPGSYTCRCRDGY 441
+A C NT GSY C C GY
Sbjct: 1351 NAKCINTDGSYKCLCLPGY 1369
Score = 62.1 bits (144), Expect = 6e-09
Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRC 384
C + + C EN C+ + YTC C G+ D +TC DV+EC E C N +C
Sbjct: 1298 CGILNGC-ENGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNRMSL-C-KNAKC 1354
Query: 385 VNVVGGYVCQCLGGYTRKDKFN 406
+N G Y C CL GY DK N
Sbjct: 1355 INTDGSYKCLCLPGYVPSDKPN 1376
Score = 58.8 bits (136), Expect = 6e-08
Identities = 55/200 (27%), Positives = 82/200 (41%), Gaps = 38/200 (19%)
Query: 222 NRCSCVHGEITCRPVE------CDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
+R C HG+ CR E CD+ + + G+ C + +CL ++ + G+
Sbjct: 799 HRHLCAHGQ--CRNTEGSFQCVCDQGYRASGL---GDHCED-INECLEDKSVCQRGDCIN 852
Query: 276 PKECAECVCHDG-----NMQCTRVD----PELACPR---------LPCDPPQQFSVPGEC 317
+C C DG N C ++ P L P+ C Q FS+ +
Sbjct: 853 TAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 912
Query: 318 CKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHG 375
+ C +D C CD + C N + C C QGFQ DG C DV+EC+ G+ G
Sbjct: 913 -RTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 971
Query: 376 HHCHSNTRCVNVVGGYVCQC 395
C NV G ++C C
Sbjct: 972 -----EAFCENVEGSFLCVC 986
Score = 55.2 bits (127), Expect = 7e-07
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Query: 403 DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCMHVDECTEGSHT 460
+ F ++ +EC G +GC + C YTC C DGY D TC+ V+EC E ++
Sbjct: 1288 NSFEELQAEEC-GILNGCE-NGRCVRVQEGYTCDCLDGYHLDTAKMTCVDVNECDELNNR 1345
Query: 461 CH--HSARCVNIDGGFRCEC 478
+A+C+N DG ++C C
Sbjct: 1346 MSLCKNAKCINTDGSYKCLC 1365
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 355 QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDEC 413
+ G +D DEC L G N C+N GY C C G Y K C ++DEC
Sbjct: 1089 EAGGENYKDADECL----LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC 1144
Query: 414 EGNTHGCHADAVCTNTPGSYTCRC 437
+ + C D C NT GSY C C
Sbjct: 1145 Q-DPSSC-IDGQCVNTEGSYNCFC 1166
Score = 47.6 bits (108), Expect = 1e-04
Identities = 56/201 (27%), Positives = 75/201 (37%), Gaps = 22/201 (10%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS--CDENATC 339
CVC D N + + + + R D P E K C Y N+ + CD N
Sbjct: 984 CVCADENQEYSPMTGQCRS-RTSTDLDVDVDQPKEEKKEC----YYNLNDASLCD-NVLA 1037
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY 399
N+ TK C C G G G C+ + C G + V G GG
Sbjct: 1038 PNV-TKQECCCTSG-AGWGDNCE-IFPCPVLGTAEFTEMCPKGKGF-VPAGESSSEAGGE 1093
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEG 457
KD DEC + C NT Y C C+ G Y+ C +DEC +
Sbjct: 1094 NYKD------ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDP 1147
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S +C +CVN +G + C C
Sbjct: 1148 S-SC-IDGQCVNTEGSYNCFC 1166
Score = 44.0 bits (99), Expect = 0.002
Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+CL GY R + C +++EC+ G + C NT GSY C C+ G+ D
Sbjct: 285 ECLPGYKRVNNTFCQDINECQ--LQGVCPNGECLNTMGSYRCTCKIGFGPD 333
Score = 34.3 bits (75), Expect = 1.4
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 8/62 (12%)
Query: 349 KCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-N 406
+C G++ T CQD++ECQ G C N C+N +G Y C C G+ F +
Sbjct: 285 ECLPGYKRVNNTFCQDINECQLQGV-----C-PNGECLNTMGSYRCTCKIGFGPDPTFSS 338
Query: 407 CV 408
CV
Sbjct: 339 CV 340
Score = 31.5 bits (68), Expect = 9.7
Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
FC ++ C + C N C+N Y C C GF D
Sbjct: 297 FCQDINECQLQGVCP-NGECLNTMGSYRCTCKIGFGPD 333
>AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein.
Length = 697
Score = 116 bits (280), Expect = 2e-25
Identities = 68/201 (33%), Positives = 93/201 (46%), Gaps = 17/201 (8%)
Query: 290 QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK 349
QC + C CD + S G+ C+ ++ C S + C+N Y C
Sbjct: 261 QCRNTEGSFQCV---CDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYDCT 314
Query: 350 CNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNC 407
C GFQ D TCQD++EC+ G C C+N G + C C G++ D C
Sbjct: 315 CPDGFQLDDNKTCQDINECEHPG-----LCGPQGECLNTEGSFHCVCQQGFSISADGRTC 369
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMHVDECTEGSHTCHHSA 465
++DEC NT C + C NT GS+ C C G++ DG C+ V+EC S C A
Sbjct: 370 EDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC-GEA 427
Query: 466 RCVNIDGGFRCECFTENCELS 486
C N++G F C C EN E S
Sbjct: 428 FCENVEGSFLCVCADENQEYS 448
Score = 114 bits (274), Expect = 1e-24
Identities = 66/212 (31%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 277 KECAEC-VCHDGNM----QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGH 331
K C + C GN+ QC + C C Q S + C+ +D C H
Sbjct: 202 KHCRDIDECQQGNLCVNGQCKNTEGSFRCT---CGQGYQLSAAKDQCE---DIDECQHRH 255
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVG 389
C + C N + C C+QG++ GL C+D++EC E + C C+N G
Sbjct: 256 LC-AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV----CQRGD-CINTAG 309
Query: 390 GYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYT 447
Y C C G+ D C +++ECE + C C NT GS+ C C+ G+ DG T
Sbjct: 310 SYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 368
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC + C C N G FRC C+
Sbjct: 369 CEDIDECVNNT-VCDSHGFCDNTAGSFRCLCY 399
Score = 103 bits (248), Expect = 2e-21
Identities = 61/163 (37%), Positives = 83/163 (50%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C +C + C+N Y C C +GF+G C DVDEC L + C
Sbjct: 123 CEDIDECLNPSTCPDEQ-CVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-----LEPNVC- 175
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
+N C N+ G Y+C C GYTR D +C ++DEC +GN C + C NT GS+ C C
Sbjct: 176 ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNL--C-VNGQCKNTEGSFRCTC 232
Query: 438 RDGYEGDGY--TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY+ C +DEC + H C H +C N +G F+C C
Sbjct: 233 GQGYQLSAAKDQCEDIDEC-QHRHLCAH-GQCRNTEGSFQCVC 273
Score = 99.1 bits (236), Expect = 4e-20
Identities = 58/163 (35%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHH 377
C +D C + H C + C N + C C GF +G C DVDEC L
Sbjct: 40 CVDIDECTQVQHLCSQGR-CENTEGSFLCICPAGFMASEEGTNCIDVDEC-----LRPDV 93
Query: 378 CHSNTRCVNVVGGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC- 435
C CVN VG + C+ C GY + C ++DEC N C D C N+PGSY C
Sbjct: 94 C-GEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECL-NPSTC-PDEQCVNSPGSYQCV 150
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +G+ G C+ VDEC E + C + C N++G + C C
Sbjct: 151 PCTEGFRGWNGQCLDVDECLE-PNVC-ANGDCSNLEGSYMCSC 191
Score = 88.2 bits (209), Expect = 8e-17
Identities = 58/173 (33%), Positives = 78/173 (45%), Gaps = 24/173 (13%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C GH C+NL +YTC C +G F C D+DEC + H S
Sbjct: 9 DICGAGH-------CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQV-----QHLCSQG 56
Query: 383 RCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-CRDG 440
RC N G ++C C G+ ++ NC++VDEC C + C NT G++ C C G
Sbjct: 57 RCENTEGSFLCICPAGFMASEEGTNCIDVDECL-RPDVC-GEGHCVNTVGAFRCEYCDSG 114
Query: 441 YE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGR 492
Y C +DEC S TC +CVN G ++C TE W G+
Sbjct: 115 YRMTQRGRCEDIDECLNPS-TC-PDEQCVNSPGSYQCVPCTEGFR---GWNGQ 162
Score = 58.8 bits (136), Expect = 6e-08
Identities = 55/200 (27%), Positives = 82/200 (41%), Gaps = 38/200 (19%)
Query: 222 NRCSCVHGEITCRPVE------CDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
+R C HG+ CR E CD+ + + G+ C + +CL ++ + G+
Sbjct: 253 HRHLCAHGQ--CRNTEGSFQCVCDQGYRASGL---GDHCED-INECLEDKSVCQRGDCIN 306
Query: 276 PKECAECVCHDG-----NMQCTRVD----PELACPR---------LPCDPPQQFSVPGEC 317
+C C DG N C ++ P L P+ C Q FS+ +
Sbjct: 307 TAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 366
Query: 318 CKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHG 375
+ C +D C CD + C N + C C QGFQ DG C DV+EC+ G+ G
Sbjct: 367 -RTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 425
Query: 376 HHCHSNTRCVNVVGGYVCQC 395
C NV G ++C C
Sbjct: 426 -----EAFCENVEGSFLCVC 440
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 355 QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDEC 413
+ G +D DEC L G N C+N GY C C G Y K C ++DEC
Sbjct: 543 EAGGENYKDADECL----LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC 598
Query: 414 EGNTHGCHADAVCTNTPGSYTCRC 437
+ + C D C NT GSY C C
Sbjct: 599 Q-DPSSC-IDGQCVNTEGSYNCFC 620
Score = 47.6 bits (108), Expect = 1e-04
Identities = 56/201 (27%), Positives = 75/201 (37%), Gaps = 22/201 (10%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS--CDENATC 339
CVC D N + + + + R D P E K C Y N+ + CD N
Sbjct: 438 CVCADENQEYSPMTGQCRS-RTSTDLDVDVDQPKEEKKEC----YYNLNDASLCD-NVLA 491
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY 399
N+ TK C C G G G C+ + C G + V G GG
Sbjct: 492 PNV-TKQECCCTSGV-GWGDNCE-IFPCPVLGTAEFTEMCPKGKGF-VPAGESSSEAGGE 547
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEG 457
KD DEC + C NT Y C C+ G Y+ C +DEC +
Sbjct: 548 NYKD------ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDP 601
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S +C +CVN +G + C C
Sbjct: 602 S-SC-IDGQCVNTEGSYNCFC 620
>AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming growth
factor beta binding protein 1 isoform LTBP-1S varian
protein.
Length = 1348
Score = 116 bits (280), Expect = 2e-25
Identities = 68/201 (33%), Positives = 93/201 (46%), Gaps = 17/201 (8%)
Query: 290 QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK 349
QC + C CD + S G+ C+ ++ C S + C+N Y C
Sbjct: 761 QCRNTEGSFQCV---CDQGYRASGLGDHCE---DINECLEDKSVCQRGDCINTAGSYDCT 814
Query: 350 CNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNC 407
C GFQ D TCQD++EC+ G C C+N G + C C G++ D C
Sbjct: 815 CPDGFQLDDNKTCQDINECEHPG-----LCGPQGECLNTEGSFHCVCQQGFSISADGRTC 869
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMHVDECTEGSHTCHHSA 465
++DEC NT C + C NT GS+ C C G++ DG C+ V+EC S C A
Sbjct: 870 EDIDECVNNTV-CDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVC-GEA 927
Query: 466 RCVNIDGGFRCECFTENCELS 486
C N++G F C C EN E S
Sbjct: 928 FCENVEGSFLCVCADENQEYS 948
Score = 114 bits (274), Expect = 1e-24
Identities = 66/212 (31%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 277 KECAEC-VCHDGNM----QCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGH 331
K C + C GN+ QC + C C Q S + C+ +D C H
Sbjct: 702 KHCRDIDECQQGNLCVNGQCKNTEGSFRCT---CGQGYQLSAAKDQCE---DIDECQHRH 755
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVG 389
C + C N + C C+QG++ GL C+D++EC E + C C+N G
Sbjct: 756 LC-AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSV----CQRGD-CINTAG 809
Query: 390 GYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYT 447
Y C C G+ D C +++ECE + C C NT GS+ C C+ G+ DG T
Sbjct: 810 SYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 868
Query: 448 CMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C +DEC + C C N G FRC C+
Sbjct: 869 CEDIDECVNNT-VCDSHGFCDNTAGSFRCLCY 899
Score = 103 bits (248), Expect = 2e-21
Identities = 61/163 (37%), Positives = 83/163 (50%), Gaps = 17/163 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C +D C +C + C+N Y C C +GF+G C DVDEC L + C
Sbjct: 623 CEDIDECLNPSTCPDEQ-CVNSPGSYQCVPCTEGFRGWNGQCLDVDEC-----LEPNVC- 675
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRC 437
+N C N+ G Y+C C GYTR D +C ++DEC +GN C + C NT GS+ C C
Sbjct: 676 ANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNL--C-VNGQCKNTEGSFRCTC 732
Query: 438 RDGYEGDGY--TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY+ C +DEC + H C H +C N +G F+C C
Sbjct: 733 GQGYQLSAAKDQCEDIDEC-QHRHLCAH-GQCRNTEGSFQCVC 773
Score = 99.1 bits (236), Expect = 4e-20
Identities = 58/163 (35%), Positives = 77/163 (47%), Gaps = 16/163 (9%)
Query: 321 CPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHH 377
C +D C + H C + C N + C C GF +G C DVDEC L
Sbjct: 540 CVDIDECTQVQHLCSQGR-CENTEGSFLCICPAGFMASEEGTNCIDVDEC-----LRPDV 593
Query: 378 CHSNTRCVNVVGGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC- 435
C CVN VG + C+ C GY + C ++DEC N C D C N+PGSY C
Sbjct: 594 C-GEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECL-NPSTC-PDEQCVNSPGSYQCV 650
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +G+ G C+ VDEC E + C + C N++G + C C
Sbjct: 651 PCTEGFRGWNGQCLDVDECLE-PNVC-ANGDCSNLEGSYMCSC 691
Score = 88.2 bits (209), Expect = 8e-17
Identities = 58/173 (33%), Positives = 78/173 (45%), Gaps = 24/173 (13%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C GH C+NL +YTC C +G F C D+DEC + H S
Sbjct: 509 DICGAGH-------CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQV-----QHLCSQG 556
Query: 383 RCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-CRDG 440
RC N G ++C C G+ ++ NC++VDEC C + C NT G++ C C G
Sbjct: 557 RCENTEGSFLCICPAGFMASEEGTNCIDVDECL-RPDVC-GEGHCVNTVGAFRCEYCDSG 614
Query: 441 YE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGR 492
Y C +DEC S TC +CVN G ++C TE W G+
Sbjct: 615 YRMTQRGRCEDIDECLNPS-TC-PDEQCVNSPGSYQCVPCTEGFR---GWNGQ 662
Score = 62.1 bits (144), Expect = 6e-09
Identities = 34/79 (43%), Positives = 41/79 (51%), Gaps = 6/79 (7%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVEVDECE--GNTHGCHA 422
+ +E G L+G C N RCV V GY C C GY K CV+V+EC+ N
Sbjct: 1248 QAEECGILNG--CE-NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCK 1304
Query: 423 DAVCTNTPGSYTCRCRDGY 441
+A C NT GSY C C GY
Sbjct: 1305 NAKCINTDGSYKCLCLPGY 1323
Score = 62.1 bits (144), Expect = 6e-09
Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRC 384
C + + C EN C+ + YTC C G+ D +TC DV+EC E C N +C
Sbjct: 1252 CGILNGC-ENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSL-C-KNAKC 1308
Query: 385 VNVVGGYVCQCLGGYTRKDKFN 406
+N G Y C CL GY DK N
Sbjct: 1309 INTDGSYKCLCLPGYVPSDKPN 1330
Score = 58.8 bits (136), Expect = 6e-08
Identities = 55/200 (27%), Positives = 82/200 (41%), Gaps = 38/200 (19%)
Query: 222 NRCSCVHGEITCRPVE------CDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFA 275
+R C HG+ CR E CD+ + + G+ C + +CL ++ + G+
Sbjct: 753 HRHLCAHGQ--CRNTEGSFQCVCDQGYRASGL---GDHCED-INECLEDKSVCQRGDCIN 806
Query: 276 PKECAECVCHDG-----NMQCTRVD----PELACPR---------LPCDPPQQFSVPGEC 317
+C C DG N C ++ P L P+ C Q FS+ +
Sbjct: 807 TAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADG 866
Query: 318 CKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHG 375
+ C +D C CD + C N + C C QGFQ DG C DV+EC+ G+ G
Sbjct: 867 -RTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCG 925
Query: 376 HHCHSNTRCVNVVGGYVCQC 395
C NV G ++C C
Sbjct: 926 -----EAFCENVEGSFLCVC 940
Score = 54.8 bits (126), Expect = 9e-07
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Query: 403 DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCMHVDECTEGSHT 460
+ F ++ +EC G +GC + C YTC C DGY D TC+ V+EC E ++
Sbjct: 1242 NSFEELQAEEC-GILNGCE-NGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNR 1299
Query: 461 CH--HSARCVNIDGGFRCEC 478
+A+C+N DG ++C C
Sbjct: 1300 MSLCKNAKCINTDGSYKCLC 1319
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 355 QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDEC 413
+ G +D DEC L G N C+N GY C C G Y K C ++DEC
Sbjct: 1043 EAGGENYKDADECL----LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDEC 1098
Query: 414 EGNTHGCHADAVCTNTPGSYTCRC 437
+ + C D C NT GSY C C
Sbjct: 1099 Q-DPSSC-IDGQCVNTEGSYNCFC 1120
Score = 47.6 bits (108), Expect = 1e-04
Identities = 56/201 (27%), Positives = 75/201 (37%), Gaps = 22/201 (10%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS--CDENATC 339
CVC D N + + + + R D P E K C Y N+ + CD N
Sbjct: 938 CVCADENQEYSPMTGQCRS-RTSTDLDVDVDQPKEEKKEC----YYNLNDASLCD-NVLA 991
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY 399
N+ TK C C G G G C+ + C G + V G GG
Sbjct: 992 PNV-TKQECCCTSG-AGWGDNCE-IFPCPVLGTAEFTEMCPKGKGF-VPAGESSSEAGGE 1047
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEG 457
KD DEC + C NT Y C C+ G Y+ C +DEC +
Sbjct: 1048 NYKD------ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDP 1101
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S +C +CVN +G + C C
Sbjct: 1102 S-SC-IDGQCVNTEGSYNCFC 1120
Score = 44.0 bits (99), Expect = 0.002
Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+CL GY R + C +++EC+ G + C NT GSY C C+ G+ D
Sbjct: 291 ECLPGYKRVNNTFCQDINECQ--LQGVCPNGECLNTMGSYRCTCKIGFGPD 339
Score = 34.3 bits (75), Expect = 1.4
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 8/62 (12%)
Query: 349 KCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-N 406
+C G++ T CQD++ECQ G C N C+N +G Y C C G+ F +
Sbjct: 291 ECLPGYKRVNNTFCQDINECQLQGV-----C-PNGECLNTMGSYRCTCKIGFGPDPTFSS 344
Query: 407 CV 408
CV
Sbjct: 345 CV 346
Score = 31.5 bits (68), Expect = 9.7
Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD 357
FC ++ C + C N C+N Y C C GF D
Sbjct: 303 FCQDINECQLQGVCP-NGECLNTMGSYRCTCKIGFGPD 339
>BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein.
Length = 807
Score = 116 bits (278), Expect = 3e-25
Identities = 61/163 (37%), Positives = 79/163 (48%), Gaps = 16/163 (9%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
VD C G C +A C N T Y C C G+QG+G C+D+DEC L+G H
Sbjct: 46 VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC--GNELNGGCVHD-- 101
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N+ G Y C C G+ D NC++VDEC N GC C N GSY C C++G+
Sbjct: 102 -CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC--QHTCVNVMGSYECCCKEGF 158
Query: 442 --EGDGYTCMHVDE----CTEGSHTCHHSARCVNIDGGFRCEC 478
+ +TC+H E C H C H + G CEC
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAP-RGSVACEC 200
Score = 96.3 bits (229), Expect = 3e-19
Identities = 56/150 (37%), Positives = 75/150 (50%), Gaps = 17/150 (11%)
Query: 333 CDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
CD TC + +T C C GF Q DG TC+D+DECQ G H C N+VG
Sbjct: 293 CDR--TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCK------NIVGS 344
Query: 391 YVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-C 448
+ C C G+ D+ +C +VDEC + C D C N PG++ C C GY G+T C
Sbjct: 345 FDCGCKKGFKLLTDEKSCQDVDECSLD-RTC--DHSCINHPGTFACACNRGYTLYGFTHC 401
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC+ + C CVN G + C+C
Sbjct: 402 GDTNECSINNGGCQQV--CVNTVGSYECQC 429
Score = 85.8 bits (203), Expect = 4e-16
Identities = 36/72 (50%), Positives = 45/72 (62%), Gaps = 3/72 (4%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC-TEGSHTCHHSARC 467
+VDEC CHADA+C NTP SY C C+ GY+G+G C +DEC E + C H C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHD--C 102
Query: 468 VNIDGGFRCECF 479
+NI G +RC CF
Sbjct: 103 LNIPGNYRCTCF 114
Score = 85.0 bits (201), Expect = 7e-16
Identities = 73/239 (30%), Positives = 99/239 (41%), Gaps = 28/239 (11%)
Query: 218 QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL---------LWGNLY 268
QRDC +C HG C+ D A+ HP T R CL N
Sbjct: 210 QRDCI-LTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTT 268
Query: 269 E--HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDY 326
G++ + C N C R + + + C P F++ + K C +D
Sbjct: 269 SVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTG-VHCSCPVGFTLQLDG-KTCKDIDE 326
Query: 327 CNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTR 383
C + CD C N+ + C C +GF+ D +CQDVDEC L HS
Sbjct: 327 CQTRNGGCDH--FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECS----LDRTCDHS--- 377
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
C+N G + C C GYT +C + +EC N GC VC NT GSY C+C GY+
Sbjct: 378 CINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQ--VCVNTVGSYECQCHPGYK 434
Score = 83.8 bits (198), Expect = 2e-15
Identities = 68/213 (31%), Positives = 86/213 (40%), Gaps = 33/213 (15%)
Query: 278 ECAECV--CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN--MGHSC 333
ECA+ + CH + C C C P Q GE + C +D C + C
Sbjct: 48 ECAQGLDDCH-ADALCQNTPTSYKCS---CKPGYQ----GEG-RQCEDIDECGNELNGGC 98
Query: 334 DENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
+ C+N+ Y C C GF DG C DVDEC E G H CVNV+G Y
Sbjct: 99 VHD--CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH------TCVNVMGSY 150
Query: 392 VCQCLGGYTRKD-KFNCVEVDE----CEGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDG 445
C C G+ D + C+ E C HGC +C P GS C CR G+E
Sbjct: 151 ECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGC--SHICKEAPRGSVACECRPGFELAK 208
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C G+ C HS C + G C C
Sbjct: 209 NQRDCILTCNHGNGGCQHS--CDDTADGPECSC 239
Score = 48.8 bits (111), Expect = 6e-05
Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 6/71 (8%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARC 467
++ C N GC D C +T C C G+ + DG TC +DEC + C H C
Sbjct: 283 METCAVNNGGC--DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--C 338
Query: 468 VNIDGGFRCEC 478
NI G F C C
Sbjct: 339 KNIVGSFDCGC 349
>AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ16792 fis, clone TBAES2007379, moderately
similar to Homo sapiens signal peptide, CUB domain,
EGF-like 2 (SCUBE2). ).
Length = 682
Score = 116 bits (278), Expect = 3e-25
Identities = 61/163 (37%), Positives = 79/163 (48%), Gaps = 16/163 (9%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
VD C G C +A C N T Y C C G+QG+G C+D+DEC L+G H
Sbjct: 46 VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC--GNELNGGCVHD-- 101
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N+ G Y C C G+ D NC++VDEC N GC C N GSY C C++G+
Sbjct: 102 -CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC--QHTCVNVMGSYECCCKEGF 158
Query: 442 --EGDGYTCMHVDE----CTEGSHTCHHSARCVNIDGGFRCEC 478
+ +TC+H E C H C H + G CEC
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAP-RGSVACEC 200
Score = 96.3 bits (229), Expect = 3e-19
Identities = 56/150 (37%), Positives = 75/150 (50%), Gaps = 17/150 (11%)
Query: 333 CDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
CD TC + +T C C GF Q DG TC+D+DECQ G H C N+VG
Sbjct: 293 CDR--TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCK------NIVGS 344
Query: 391 YVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-C 448
+ C C G+ D+ +C +VDEC + C D C N PG++ C C GY G+T C
Sbjct: 345 FDCGCKKGFKLLTDEKSCQDVDECSLD-RTC--DHSCINHPGTFACACNRGYTLYGFTHC 401
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC+ + C CVN G + C+C
Sbjct: 402 GDTNECSINNGGCQQV--CVNTVGSYECQC 429
Score = 85.8 bits (203), Expect = 4e-16
Identities = 36/72 (50%), Positives = 45/72 (62%), Gaps = 3/72 (4%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC-TEGSHTCHHSARC 467
+VDEC CHADA+C NTP SY C C+ GY+G+G C +DEC E + C H C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHD--C 102
Query: 468 VNIDGGFRCECF 479
+NI G +RC CF
Sbjct: 103 LNIPGNYRCTCF 114
Score = 85.8 bits (203), Expect = 4e-16
Identities = 73/239 (30%), Positives = 100/239 (41%), Gaps = 28/239 (11%)
Query: 218 QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL---------LWGNLY 268
QRDC +C HG C+ D A+ HP T R CL N
Sbjct: 210 QRDCI-LTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTT 268
Query: 269 E--HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDY 326
G++ ++ C N C R + + + C P F++ + K C +D
Sbjct: 269 SVVDGDKRVKRQLLMETCAVNNGGCDRTCKDTSTG-VHCSCPVGFTLQLDG-KTCKDIDE 326
Query: 327 CNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTR 383
C + CD C N+ + C C +GF+ D +CQDVDEC L HS
Sbjct: 327 CQTRNGGCDH--FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECS----LDRTCDHS--- 377
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
C+N G + C C GYT +C + +EC N GC VC NT GSY C+C GY+
Sbjct: 378 CINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQ--VCVNTVGSYECQCHPGYK 434
Score = 83.8 bits (198), Expect = 2e-15
Identities = 68/213 (31%), Positives = 86/213 (40%), Gaps = 33/213 (15%)
Query: 278 ECAECV--CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN--MGHSC 333
ECA+ + CH + C C C P Q GE + C +D C + C
Sbjct: 48 ECAQGLDDCH-ADALCQNTPTSYKCS---CKPGYQ----GEG-RQCEDIDECGNELNGGC 98
Query: 334 DENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
+ C+N+ Y C C GF DG C DVDEC E G H CVNV+G Y
Sbjct: 99 VHD--CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH------TCVNVMGSY 150
Query: 392 VCQCLGGYTRKD-KFNCVEVDE----CEGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDG 445
C C G+ D + C+ E C HGC +C P GS C CR G+E
Sbjct: 151 ECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGC--SHICKEAPRGSVACECRPGFELAK 208
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C G+ C HS C + G C C
Sbjct: 209 NQRDCILTCNHGNGGCQHS--CDDTADGPECSC 239
Score = 48.8 bits (111), Expect = 6e-05
Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 6/71 (8%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARC 467
++ C N GC D C +T C C G+ + DG TC +DEC + C H C
Sbjct: 283 METCAVNNGGC--DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--C 338
Query: 468 VNIDGGFRCEC 478
NI G F C C
Sbjct: 339 KNIVGSFDCGC 349
>AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens
cDNA FLJ41044 fis, clone NT2RP7000466, highly similar
to Mus musculus CUB domain and EGF-like repeat
containing 1 (Cegf1). ).
Length = 971
Score = 116 bits (278), Expect = 3e-25
Identities = 61/163 (37%), Positives = 79/163 (48%), Gaps = 16/163 (9%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
VD C G C +A C N T Y C C G+QG+G C+D+DEC L+G H
Sbjct: 46 VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC--GNELNGGCVHD-- 101
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N+ G Y C C G+ D NC++VDEC N GC C N GSY C C++G+
Sbjct: 102 -CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC--QHTCVNVMGSYECCCKEGF 158
Query: 442 --EGDGYTCMHVDE----CTEGSHTCHHSARCVNIDGGFRCEC 478
+ +TC+H E C H C H + G CEC
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAP-RGSVACEC 200
Score = 96.3 bits (229), Expect = 3e-19
Identities = 56/150 (37%), Positives = 75/150 (50%), Gaps = 17/150 (11%)
Query: 333 CDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
CD TC + +T C C GF Q DG TC+D+DECQ G H C N+VG
Sbjct: 293 CDR--TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCK------NIVGS 344
Query: 391 YVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-C 448
+ C C G+ D+ +C +VDEC + C D C N PG++ C C GY G+T C
Sbjct: 345 FDCGCKKGFKLLTDEKSCQDVDECSLD-RTC--DHSCINHPGTFACACNRGYTLYGFTHC 401
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC+ + C CVN G + C+C
Sbjct: 402 GDTNECSINNGGCQQV--CVNTVGSYECQC 429
Score = 87.0 bits (206), Expect = 2e-16
Identities = 81/275 (29%), Positives = 110/275 (40%), Gaps = 30/275 (10%)
Query: 218 QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL---------LWGNLY 268
QRDC +C HG C+ D A+ HP T R CL N
Sbjct: 210 QRDCI-LTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTT 268
Query: 269 E--HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDY 326
G++ + C N C R + + + C P F++ + K C +D
Sbjct: 269 SVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTG-VHCSCPVGFTLQLDG-KTCKDIDE 326
Query: 327 CNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTR 383
C + CD C N+ + C C +GF+ D +CQDVDEC L HS
Sbjct: 327 CQTRNGGCDH--FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECS----LDRTCDHS--- 377
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE- 442
C+N G + C C GYT +C + +EC N GC VC NT GSY C+C GY+
Sbjct: 378 CINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQ--VCVNTVGSYECQCHPGYKL 435
Query: 443 -GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+ C+ V S + S C GG C
Sbjct: 436 HWNKKDCVEVKGLLPTSVSPRVSLHCGKSGGGDGC 470
Score = 85.8 bits (203), Expect = 4e-16
Identities = 36/72 (50%), Positives = 45/72 (62%), Gaps = 3/72 (4%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC-TEGSHTCHHSARC 467
+VDEC CHADA+C NTP SY C C+ GY+G+G C +DEC E + C H C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHD--C 102
Query: 468 VNIDGGFRCECF 479
+NI G +RC CF
Sbjct: 103 LNIPGNYRCTCF 114
Score = 83.8 bits (198), Expect = 2e-15
Identities = 68/213 (31%), Positives = 86/213 (40%), Gaps = 33/213 (15%)
Query: 278 ECAECV--CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN--MGHSC 333
ECA+ + CH + C C C P Q GE + C +D C + C
Sbjct: 48 ECAQGLDDCH-ADALCQNTPTSYKCS---CKPGYQ----GEG-RQCEDIDECGNELNGGC 98
Query: 334 DENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
+ C+N+ Y C C GF DG C DVDEC E G H CVNV+G Y
Sbjct: 99 VHD--CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH------TCVNVMGSY 150
Query: 392 VCQCLGGYTRKD-KFNCVEVDE----CEGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDG 445
C C G+ D + C+ E C HGC +C P GS C CR G+E
Sbjct: 151 ECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGC--SHICKEAPRGSVACECRPGFELAK 208
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C G+ C HS C + G C C
Sbjct: 209 NQRDCILTCNHGNGGCQHS--CDDTADGPECSC 239
Score = 48.8 bits (111), Expect = 6e-05
Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 6/71 (8%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARC 467
++ C N GC D C +T C C G+ + DG TC +DEC + C H C
Sbjct: 283 METCAVNNGGC--DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--C 338
Query: 468 VNIDGGFRCEC 478
NI G F C C
Sbjct: 339 KNIVGSFDCGC 349
>AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein.
Length = 999
Score = 116 bits (278), Expect = 3e-25
Identities = 61/163 (37%), Positives = 79/163 (48%), Gaps = 16/163 (9%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
VD C G C +A C N T Y C C G+QG+G C+D+DEC L+G H
Sbjct: 46 VDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDEC--GNELNGGCVHD-- 101
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N+ G Y C C G+ D NC++VDEC N GC C N GSY C C++G+
Sbjct: 102 -CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC--QHTCVNVMGSYECCCKEGF 158
Query: 442 --EGDGYTCMHVDE----CTEGSHTCHHSARCVNIDGGFRCEC 478
+ +TC+H E C H C H + G CEC
Sbjct: 159 FLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAP-RGSVACEC 200
Score = 96.3 bits (229), Expect = 3e-19
Identities = 56/150 (37%), Positives = 75/150 (50%), Gaps = 17/150 (11%)
Query: 333 CDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
CD TC + +T C C GF Q DG TC+D+DECQ G H C N+VG
Sbjct: 293 CDR--TCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCK------NIVGS 344
Query: 391 YVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-C 448
+ C C G+ D+ +C +VDEC + C D C N PG++ C C GY G+T C
Sbjct: 345 FDCGCKKGFKLLTDEKSCQDVDECSLD-RTC--DHSCINHPGTFACACNRGYTLYGFTHC 401
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC+ + C CVN G + C+C
Sbjct: 402 GDTNECSINNGGCQQV--CVNTVGSYECQC 429
Score = 87.0 bits (206), Expect = 2e-16
Identities = 81/275 (29%), Positives = 110/275 (40%), Gaps = 30/275 (10%)
Query: 218 QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCL---------LWGNLY 268
QRDC +C HG C+ D A+ HP T R CL N
Sbjct: 210 QRDCI-LTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTT 268
Query: 269 E--HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDY 326
G++ + C N C R + + + C P F++ + K C +D
Sbjct: 269 SVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTG-VHCSCPVGFTLQLDG-KTCKDIDE 326
Query: 327 CNMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTR 383
C + CD C N+ + C C +GF+ D +CQDVDEC L HS
Sbjct: 327 CQTRNGGCDH--FCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECS----LDRTCDHS--- 377
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE- 442
C+N G + C C GYT +C + +EC N GC VC NT GSY C+C GY+
Sbjct: 378 CINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQ--VCVNTVGSYECQCHPGYKL 435
Query: 443 -GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+ C+ V S + S C GG C
Sbjct: 436 HWNKKDCVEVKGLLPTSVSPRVSLHCGKSGGGDGC 470
Score = 85.8 bits (203), Expect = 4e-16
Identities = 36/72 (50%), Positives = 45/72 (62%), Gaps = 3/72 (4%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC-TEGSHTCHHSARC 467
+VDEC CHADA+C NTP SY C C+ GY+G+G C +DEC E + C H C
Sbjct: 45 DVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHD--C 102
Query: 468 VNIDGGFRCECF 479
+NI G +RC CF
Sbjct: 103 LNIPGNYRCTCF 114
Score = 83.8 bits (198), Expect = 2e-15
Identities = 68/213 (31%), Positives = 86/213 (40%), Gaps = 33/213 (15%)
Query: 278 ECAECV--CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN--MGHSC 333
ECA+ + CH + C C C P Q GE + C +D C + C
Sbjct: 48 ECAQGLDDCH-ADALCQNTPTSYKCS---CKPGYQ----GEG-RQCEDIDECGNELNGGC 98
Query: 334 DENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
+ C+N+ Y C C GF DG C DVDEC E G H CVNV+G Y
Sbjct: 99 VHD--CLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH------TCVNVMGSY 150
Query: 392 VCQCLGGYTRKD-KFNCVEVDE----CEGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDG 445
C C G+ D + C+ E C HGC +C P GS C CR G+E
Sbjct: 151 ECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGC--SHICKEAPRGSVACECRPGFELAK 208
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ C G+ C HS C + G C C
Sbjct: 209 NQRDCILTCNHGNGGCQHS--CDDTADGPECSC 239
Score = 48.8 bits (111), Expect = 6e-05
Identities = 26/71 (36%), Positives = 33/71 (46%), Gaps = 6/71 (8%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARC 467
++ C N GC D C +T C C G+ + DG TC +DEC + C H C
Sbjct: 283 METCAVNNGGC--DRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHF--C 338
Query: 468 VNIDGGFRCEC 478
NI G F C C
Sbjct: 339 KNIVGSFDCGC 349
>Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP1-100N22 on chromosome 22q13.31-13.33. ).
Length = 988
Score = 115 bits (277), Expect = 5e-25
Identities = 59/163 (36%), Positives = 80/163 (49%), Gaps = 15/163 (9%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
VD C+ G C +A C N Y C C G++G+G C+D+DEC E +G H
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDEC-ENDYYNGGCVH--- 89
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N+ G Y C C G+ D NC++VDEC+ N GC +C N GSY C+C G+
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC--QQICVNAMGSYECQCHSGF 147
Query: 442 --EGDGYTCMHVD----ECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +TC+H C H C H R GG C+C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICR-ETPKGGVACDC 189
Score = 88.2 bits (209), Expect = 8e-17
Identities = 34/72 (47%), Positives = 43/72 (59%)
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
V+VDEC T CH DA+C NTP SY C C+ GY+G+G C +DEC + C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 468 VNIDGGFRCECF 479
+NI G +RC CF
Sbjct: 92 INIPGNYRCTCF 103
Score = 81.4 bits (192), Expect = 9e-15
Identities = 63/216 (29%), Positives = 91/216 (42%), Gaps = 25/216 (11%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CDE 335
+ C E C N C R + A + C P F++ + K C ++ C + + CD
Sbjct: 239 RTCIE-TCAVNNGGCDRTCKDTATG-VRCSCPVGFTLQPDG-KTCKDINECLVNNGGCDH 295
Query: 336 NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N + C C +G++ D TCQD+DEC C + C+N G + C
Sbjct: 296 --FCRNTVGSFECGCRKGYKLLTDERTCQDIDECS-----FERTC--DHICINSPGSFQC 346
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHV 451
C GY +C +VDEC + C D C NT GSY C C G +G C+
Sbjct: 347 LCHRGYILYGTTHCGDVDECSMSNGSC--DQGCVNTKGSYECVCPPGRRLHWNGKDCVET 404
Query: 452 DECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+C + T + + GG E+C LSC
Sbjct: 405 GKCLSRAKTSPRAQLSCSKAGG------VESCFLSC 434
Score = 48.4 bits (110), Expect = 8e-05
Identities = 43/168 (25%), Positives = 62/168 (36%), Gaps = 25/168 (14%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGF--QGDGLTC----QDVDECQEAGGL 373
C VD C + C + C+N Y C+C+ GF + TC + C
Sbjct: 115 CLDVDECQDNNGGCQQ--ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHG 172
Query: 374 HGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGS 432
H C + GG C C G+ +++ +C C GC C +T
Sbjct: 173 CAHICRETPK-----GGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHS--CEDTDTG 223
Query: 433 YTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
TC C Y DG TC ++ C + C + C + G RC C
Sbjct: 224 PTCGCHQKYALHSDGRTC--IETCAVNNGGCDRT--CKDTATGVRCSC 267
>Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP3-526I14 on chromosome 22. ).
Length = 988
Score = 115 bits (277), Expect = 5e-25
Identities = 59/163 (36%), Positives = 80/163 (49%), Gaps = 15/163 (9%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
VD C+ G C +A C N Y C C G++G+G C+D+DEC E +G H
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDEC-ENDYYNGGCVH--- 89
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N+ G Y C C G+ D NC++VDEC+ N GC +C N GSY C+C G+
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC--QQICVNAMGSYECQCHSGF 147
Query: 442 --EGDGYTCMHVD----ECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +TC+H C H C H R GG C+C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICR-ETPKGGVACDC 189
Score = 88.2 bits (209), Expect = 8e-17
Identities = 34/72 (47%), Positives = 43/72 (59%)
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
V+VDEC T CH DA+C NTP SY C C+ GY+G+G C +DEC + C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 468 VNIDGGFRCECF 479
+NI G +RC CF
Sbjct: 92 INIPGNYRCTCF 103
Score = 81.4 bits (192), Expect = 9e-15
Identities = 63/216 (29%), Positives = 91/216 (42%), Gaps = 25/216 (11%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CDE 335
+ C E C N C R + A + C P F++ + K C ++ C + + CD
Sbjct: 239 RTCIE-TCAVNNGGCDRTCKDTATG-VRCSCPVGFTLQPDG-KTCKDINECLVNNGGCDH 295
Query: 336 NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N + C C +G++ D TCQD+DEC C + C+N G + C
Sbjct: 296 --FCRNTVGSFECGCRKGYKLLTDERTCQDIDECS-----FERTC--DHICINSPGSFQC 346
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHV 451
C GY +C +VDEC + C D C NT GSY C C G +G C+
Sbjct: 347 LCHRGYILYGTTHCGDVDECSMSNGSC--DQGCVNTKGSYECVCPPGRRLHWNGKDCVET 404
Query: 452 DECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+C + T + + GG E+C LSC
Sbjct: 405 GKCLSRAKTSPRAQLSCSKAGG------VESCFLSC 434
Score = 48.4 bits (110), Expect = 8e-05
Identities = 43/168 (25%), Positives = 62/168 (36%), Gaps = 25/168 (14%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGF--QGDGLTC----QDVDECQEAGGL 373
C VD C + C + C+N Y C+C+ GF + TC + C
Sbjct: 115 CLDVDECQDNNGGCQQ--ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHG 172
Query: 374 HGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGS 432
H C + GG C C G+ +++ +C C GC C +T
Sbjct: 173 CAHICRETPK-----GGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHS--CEDTDTG 223
Query: 433 YTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
TC C Y DG TC ++ C + C + C + G RC C
Sbjct: 224 PTCGCHQKYALHSDGRTC--IETCAVNNGGCDRT--CKDTATGVRCSC 267
>Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding
protein-4 protein.
Length = 1587
Score = 115 bits (277), Expect = 5e-25
Identities = 98/274 (35%), Positives = 115/274 (41%), Gaps = 32/274 (11%)
Query: 223 RCSCVHG--EITCRPVEC-DRAEC-KNPVLHP-GECCPTCLRQCLLWGNLYEHGERFAP- 276
RCSC G + RP C D EC + P GEC T Y G R A
Sbjct: 822 RCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 881
Query: 277 ---KECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN-MGH 331
EC+E +C G CT D C C P + G C VD C G
Sbjct: 882 LDVDECSEEDLCQSGI--CTNTDGSFECI---CPPGHR---AGPDLASCLDVDECRERGP 933
Query: 332 SCDENATCMNLNTKYTC--KCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
+ + C N Y C C+ G+ G TC DVDECQE +G RC N
Sbjct: 934 ALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQE----YGPEICGAQRCENTP 989
Query: 389 GGYVCQ--CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--D 444
G Y C C GY C +VDEC N C A AVC N PGS+ C C GYEG D
Sbjct: 990 GSYRCTPACDPGYQPTPGGGCQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARD 1048
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G C+ V+EC C +A C N++G F C C
Sbjct: 1049 GRHCVDVNECETLQGVC-GAALCENVEGSFLCVC 1081
Score = 100 bits (240), Expect = 1e-20
Identities = 57/164 (34%), Positives = 69/164 (42%), Gaps = 14/164 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHC 378
C VD C C N + C C GFQ + G C+DVDEC+ H
Sbjct: 713 CQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECEN------HLA 766
Query: 379 HSNTRCVNVVGGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G + C+ C G+ + C +VDEC C CTNT GS+ C C
Sbjct: 767 CPGQECVNSPGSFQCRTCPSGH-HLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 825
Query: 438 RDGY---EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY G C V+EC EG C C+N DG F C C
Sbjct: 826 APGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACTC 868
Score = 96.3 bits (229), Expect = 3e-19
Identities = 63/192 (32%), Positives = 81/192 (42%), Gaps = 20/192 (10%)
Query: 293 RVDPELACPRLPCDPPQQFSVPGECCKFCP-GVDYCNMGHSCDENATCMNLNTKYTCKCN 351
R PEL P +P + G C C G C++ + YTC C+
Sbjct: 484 RPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGR-------CISRPSGYTCACD 536
Query: 352 QGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-NCV 408
GF+ G C DVDEC+ C RC N G + C C G+ + C+
Sbjct: 537 SGFRLSPQGTRCIDVDECRRVPP----PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECL 591
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMHVDECTEGSHTCHHSAR 466
+VDEC C C NTPGS+ C C GY+ G +C VDECT+ C
Sbjct: 592 DVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGG- 649
Query: 467 CVNIDGGFRCEC 478
C N+ G FRC C
Sbjct: 650 CKNLPGSFRCVC 661
Score = 89.0 bits (211), Expect = 5e-17
Identities = 87/290 (30%), Positives = 112/290 (38%), Gaps = 37/290 (12%)
Query: 204 CYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAECKN--PVLHPGEC--CPT 256
C N V G R C+C G ++ + C D EC+ P PG C P
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 257 CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPEL---ACPRLP----CDPPQ 309
R C+ G R P+ AEC+ D +C RV P C P C P
Sbjct: 572 SFR-CVCGP-----GFRAGPR-AAECLDVD---ECHRVPPPCDLGRCENTPGSFLCVCPA 621
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
+ C VD C C NL + C C GF+G +DVDEC +
Sbjct: 622 GYQAAPHGAS-CQDVDECTQSPGLCGRGGCKNLPGSFRCVCPAGFRGSACE-EDVDECAQ 679
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
G RC N G + C C G+ +R C +VDEC + C C N
Sbjct: 680 EPPPCG-----PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC-TYGRCEN 733
Query: 429 TPGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
T GS+ C C G++ + G C VDEC +H CVN G F+C
Sbjct: 734 TEGSFQCVCPMGFQPNTAGSECEDVDECE--NHLACPGQECVNSPGSFQC 781
Score = 79.4 bits (187), Expect = 4e-14
Identities = 52/161 (32%), Positives = 62/161 (38%), Gaps = 11/161 (6%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHC 378
C VD C C N + C C GF+ C DVDEC C
Sbjct: 548 CIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPP----PC 603
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
RC N G ++C C GY +C +VDEC + C C N PGS+ C C
Sbjct: 604 DLG-RCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGG-CKNLPGSFRCVC 661
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ G VDEC + C RC N G F C C
Sbjct: 662 PAGFRGSACE-EDVDECAQEPPPCG-PGRCDNTAGSFHCAC 700
Score = 73.3 bits (172), Expect = 2e-12
Identities = 53/161 (32%), Positives = 69/161 (42%), Gaps = 16/161 (9%)
Query: 287 GNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN-MGHSCDENATCMNLNTK 345
G+ +C C R CDP G C VD C G C N
Sbjct: 937 GSQRCENSPGSYRCVR-DCDPGYHAGPEGTC----DDVDECQEYGPEICGAQRCENTPGS 991
Query: 346 YTCK--CNQGFQGD-GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-R 401
Y C C+ G+Q G CQDVDEC+ C ++ C N+ G + C C GY
Sbjct: 992 YRCTPACDPGYQPTPGGGCQDVDECRNRS-----FCGAHAVCQNLPGSFQCLCDQGYEGA 1046
Query: 402 KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
+D +CV+V+ECE C A A+C N GS+ C C + E
Sbjct: 1047 RDGRHCVDVNECETLQGVCGA-ALCENVEGSFLCVCPNSPE 1086
Score = 60.1 bits (139), Expect = 2e-08
Identities = 33/76 (43%), Positives = 41/76 (53%), Gaps = 8/76 (10%)
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GYTCMHVDECTE---GSHTCH 462
+E +EC G GC D C P +TCRC DGY D C+ ++EC E S C
Sbjct: 1495 LEAEEC-GILDGCTNDR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC- 1551
Query: 463 HSARCVNIDGGFRCEC 478
+ARC+N DG FRC C
Sbjct: 1552 VNARCLNTDGSFRCIC 1567
Score = 58.4 bits (135), Expect = 7e-08
Identities = 34/91 (37%), Positives = 38/91 (41%), Gaps = 6/91 (6%)
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDECE 414
GD +DVDECQ C S CVN GY C C G Y + C++ DEC
Sbjct: 1209 GDLSLRRDVDECQL---FRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECA 1264
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
C C NT GSY C C DG
Sbjct: 1265 DEEPACEGGR-CVNTVGSYHCTCEPPLVLDG 1294
Score = 56.8 bits (131), Expect = 2e-07
Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 10/81 (12%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD--KFNCVEVDEC---EGNTHGC 420
E +E G L G C +N RCV V G+ C+C GY R D + CV+++EC E + C
Sbjct: 1496 EAEECGILDG--C-TNDRCVRVPEGFTCRCFDGY-RLDMTRMACVDINECDEAEAASPLC 1551
Query: 421 HADAVCTNTPGSYTCRCRDGY 441
+A C NT GS+ C CR G+
Sbjct: 1552 -VNARCLNTDGSFRCICRPGF 1571
Score = 52.0 bits (119), Expect = 6e-06
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEGSHTCHHSAR 466
+VDEC+ VC NT Y+C C +G Y C+ DEC + C R
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPAC-EGGR 1274
Query: 467 CVNIDGGFRCEC 478
CVN G + C C
Sbjct: 1275 CVNTVGSYHCTC 1286
Score = 46.4 bits (105), Expect = 3e-04
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
Query: 304 PCDPPQQFSVPGECCKFCPGVDY--CNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GL 359
P +PP+ S G + ++ C + C N C+ + +TC+C G++ D +
Sbjct: 1475 PEEPPEGGSYAGSLAEPYEELEAEECGILDGCT-NDRCVRVPEGFTCRCFDGYRLDMTRM 1533
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY 399
C D++EC EA C N RC+N G + C C G+
Sbjct: 1534 ACVDINECDEAEAA-SPLC-VNARCLNTDGSFRCICRPGF 1571
Score = 41.5 bits (93), Expect = 0.009
Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 324 VDYCNMGHS--CDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHCH 379
VD C + C ++ C+N Y+C C+ G + L C D DEC + C
Sbjct: 1217 VDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD----EEPACE 1271
Query: 380 SNTRCVNVVGGYVCQC 395
RCVN VG Y C C
Sbjct: 1272 GG-RCVNTVGSYHCTC 1286
Score = 41.1 bits (92), Expect = 0.012
Identities = 39/125 (31%), Positives = 53/125 (42%), Gaps = 20/125 (16%)
Query: 358 GLTCQDVDECQEAGGLHG-HHCH------SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEV 410
GL Q+V C+ AG G H C N+ V+ G C G+ R + +C +V
Sbjct: 267 GLRTQEVC-CRGAGLAWGVHDCQLCSERLGNSERVSAPDG---PCPTGFERVNG-SCEDV 321
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCV 468
DEC H + C NT G YTC C DG+ + +C+ +E C R
Sbjct: 322 DECATGGRCQHGE--CANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLR-- 377
Query: 469 NIDGG 473
DGG
Sbjct: 378 --DGG 380
Score = 39.5 bits (88), Expect = 0.037
Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 10/82 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCV 408
C GF+ +C+DVDEC G C + C N GGY C C G+ + +C+
Sbjct: 307 CPTGFERVNGSCEDVDECATGG-----RC-QHGECANTRGGYTCVCPDGFLLDSSRSSCI 360
Query: 409 E---VDECEGNTHGCHADAVCT 427
+ E +G D C+
Sbjct: 361 SQHVISEAKGPCFRVLRDGGCS 382
Score = 38.3 bits (85), Expect = 0.084
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 437 CRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G+E +C VDEC G C H C N GG+ C C
Sbjct: 307 CPTGFERVNGSCEDVDECATGGR-CQHG-ECANTRGGYTCVC 346
Score = 32.7 bits (71), Expect = 4.2
Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
C VD C G C ++ C N YTC C GF
Sbjct: 318 CEDVDECATGGRC-QHGECANTRGGYTCVCPDGF 350
>X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein.
Length = 517
Score = 115 bits (277), Expect = 5e-25
Identities = 78/247 (31%), Positives = 109/247 (44%), Gaps = 34/247 (13%)
Query: 258 LRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCTRVDPELACPRLPCDPPQQF 311
+ +C + +L HG+ +C C G CT +D P L C Q
Sbjct: 233 INECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL-CGRGQCV 291
Query: 312 SVPG--EC-C-----------KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-- 355
+ PG EC C K C +D C C N Y C+C G Q
Sbjct: 292 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 351
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECE 414
+ C D++EC+ L H C N RCVN++G Y C C GY + D+ CV++DEC
Sbjct: 352 PNISACIDINECE----LSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS 406
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDG 472
GC + CTN+ GSY C C+ G+ D +C +DEC + + C +C NI G
Sbjct: 407 IMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIPG 463
Query: 473 GFRCECF 479
+RC C+
Sbjct: 464 EYRCLCY 470
Score = 115 bits (276), Expect = 6e-25
Identities = 67/182 (36%), Positives = 83/182 (45%), Gaps = 16/182 (8%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGL 359
R C P Q S P C ++ C + N C+NL KY C CN G+ D L
Sbjct: 341 RCECPPGHQLS-PN--ISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRL 397
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTH 418
C D+DEC G C T C N G Y C C G+ D+ +C ++DECE N +
Sbjct: 398 FCVDIDECSIMNG----GC--ETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPN 451
Query: 419 GCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C CTN PG Y C C DG+ D TC+ V+EC + C S C N G F C
Sbjct: 452 ICDG-GQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNIC-LSGTCENTKGSFIC 509
Query: 477 EC 478
C
Sbjct: 510 HC 511
Score = 103 bits (247), Expect = 2e-21
Identities = 68/214 (31%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG 330
G + +EC EC M+ T EL CPR P ++ + G+ F ++ C M
Sbjct: 189 GAAWGTEECEECP-----MRNTPEYEEL-CPRGPGFATKEIT-NGK--PFFKDINECKMI 239
Query: 331 HSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
S + C N + C+C+ GF D C D+DEC+ + L G +CVN
Sbjct: 240 PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCG-----RGQCVNTP 294
Query: 389 GGYVCQCLGGYTRKDKF--NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GD 444
G + C+C GY NC+++DEC+ + C VC NT GSY C C G++ +
Sbjct: 295 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPN 353
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+ ++EC +H C + RCVN+ G ++C C
Sbjct: 354 ISACIDINECELSAHLC-PNGRCVNLIGKYQCAC 386
Score = 85.0 bits (201), Expect = 7e-16
Identities = 45/128 (35%), Positives = 62/128 (48%), Gaps = 12/128 (9%)
Query: 320 FCPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
FC +D C+ M C+ C N Y C C GF D +C D+DEC++ +
Sbjct: 398 FCVDIDECSIMNGGCE--TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNI--- 452
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C +C N+ G Y C C G+ +D CV+V+EC+ N + C C NT GS+ C
Sbjct: 453 -CDGG-QCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNIC-LSGTCENTKGSFIC 509
Query: 436 RCRDGYEG 443
C GY G
Sbjct: 510 HCDMGYSG 517
Score = 41.9 bits (94), Expect = 0.007
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHV 451
C GY+R C ++DECE C + +C NT GS+ C+C G + G C+ +
Sbjct: 100 CGKGYSRIKGTQCEDIDECEVFPGVCK-NGLCVNTRGSFKCQCPSGMTLDATGRICLDI 157
Score = 39.5 bits (88), Expect = 0.037
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 350 CNQGFQG-DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
C +G+ G C+D+DEC+ G+ C N CVN G + CQC G T
Sbjct: 100 CGKGYSRIKGTQCEDIDECEVFPGV----C-KNGLCVNTRGSFKCQCPSGMT 146
Score = 39.1 bits (87), Expect = 0.048
Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 24/121 (19%)
Query: 381 NTRCVNVVGGYVCQCLGGYTRKD-KFNCVE----------VD-ECEGNTHGCHADAVCTN 428
N C N G ++C+C T K C+E +D CE N +G + C +
Sbjct: 22 NGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCS 81
Query: 429 TPGSY------TCR----CRDGYEG-DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCE 477
+ G+ C+ C GY G C +DEC C + CVN G F+C+
Sbjct: 82 SLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGL-CVNTRGSFKCQ 140
Query: 478 C 478
C
Sbjct: 141 C 141
Score = 34.3 bits (75), Expect = 1.4
Identities = 27/95 (28%), Positives = 39/95 (41%), Gaps = 20/95 (21%)
Query: 281 ECVCHDG------NMQCTRVDPELACPRLPCDPPQQFSVPGE--C-C----------KFC 321
EC C G CT +D P + CD Q ++PGE C C K C
Sbjct: 424 ECSCQPGFALMPDQRSCTDIDECEDNPNI-CDGGQCTNIPGEYRCLCYDGFMASEDMKTC 482
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG 356
V+ C++ + + TC N + C C+ G+ G
Sbjct: 483 VDVNECDLNPNICLSGTCENTKGSFICHCDMGYSG 517
>U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homolog
mRNA, partial cds. ).
Length = 446
Score = 115 bits (277), Expect = 5e-25
Identities = 63/189 (33%), Positives = 91/189 (48%), Gaps = 24/189 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C D C G H+CDENA C N ++C C G+ G+G C+ C+E G +G C
Sbjct: 92 CTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAF--CEE-GCRYGGTCV 148
Query: 380 SNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
+ +CV C G+T +C ++DEC CH + C N PG + C CR
Sbjct: 149 APNKCV---------CPSGFTGS---HCEKDIDECSEGIIECHNHSRCVNLPGWHHCECR 196
Query: 439 DGYEGDGY------TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC-FTENCELSCSWQG 491
G+ DG +C+ +DEC +HTC + + C+N+ GGF C C +C C +G
Sbjct: 197 SGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPCGPSCSGDCPHEG 256
Query: 492 RVVSEGATW 500
+ G W
Sbjct: 257 GLKHNGQVW 265
Score = 113 bits (271), Expect = 2e-24
Identities = 55/133 (41%), Positives = 71/133 (53%), Gaps = 9/133 (6%)
Query: 355 QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE 414
+GD C+D+DEC H+CH+NT CVN+ G Y C C+ GY R D F+C E DEC
Sbjct: 44 RGDSAYCEDIDEC----AAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECG 99
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE--CTEGSHTCHHSARCVNIDG 472
H C +A+CTNT ++C C+ GY G+G C E C G TC +CV G
Sbjct: 100 SGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGG-TCVAPNKCVCPSG 158
Query: 473 --GFRCECFTENC 483
G CE + C
Sbjct: 159 FTGSHCEKDIDEC 171
Score = 97.1 bits (231), Expect = 2e-19
Identities = 56/161 (34%), Positives = 72/161 (44%), Gaps = 16/161 (9%)
Query: 320 FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
+C +D C H C N C+NL Y C C G+ + D +C + DEC G H+
Sbjct: 49 YCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDEC----GSGQHN 104
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C N C N V G+ C C GY C CE GC C P C C
Sbjct: 105 CDENAICTNTVQGHSCTCKPGYVGNGTI-CRAF--CE---EGCRYGGTCV-APNK--CVC 155
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ G + +DEC+EG CH+ +RCVN+ G CEC
Sbjct: 156 PSGFTG-SHCEKDIDECSEGIIECHNHSRCVNLPGWHHCEC 195
Score = 82.6 bits (195), Expect = 4e-15
Identities = 34/80 (42%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY-EGDGYTCMHVDECTEGS 458
+R D C ++DEC H CHA+ VC N PG Y C C GY D ++C DEC G
Sbjct: 43 SRGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQ 102
Query: 459 HTCHHSARCVNIDGGFRCEC 478
H C +A C N G C C
Sbjct: 103 HNCDENAICTNTVQGHSCTC 122
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/152 (31%), Positives = 65/152 (42%), Gaps = 22/152 (14%)
Query: 200 CQKSCYSNGTVHADGATW---QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPT 256
C C G + +G W + C+ CSC G+I CR CD C+NP CCP
Sbjct: 248 CSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACD---CQNPSADL-FCCPE 303
Query: 257 C----LRQCLLWG--NLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
C QCL LY G+ + C +C C +G + C L CP L C+
Sbjct: 304 CDTRVTSQCLDQNGHKLYRSGDNWT-HSCQQCRCLEGEVDCW----PLTCPNLSCE--YT 356
Query: 311 FSVPGECCKFCPGVDYCNMGH-SCDENATCMN 341
+ GECC C D C + + D TC++
Sbjct: 357 AILEGECCPRCVS-DPCLADNITYDIRKTCLD 387
Score = 60.1 bits (139), Expect = 2e-08
Identities = 24/46 (52%), Positives = 28/46 (60%), Gaps = 3/46 (6%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCW 598
CCP CD R C Q H + +RSG+ W + CQ C CL GEVDCW
Sbjct: 300 CCPECDTRVTSQCLDQNGHKL-YRSGDNWTHSCQQCRCLEGEVDCW 344
Score = 56.8 bits (131), Expect = 2e-07
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 197 QCDCQ--KSCYS-NG-TVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGE 252
+CD + C NG ++ G W C +C C+ GE+ C P+ C C+ + GE
Sbjct: 303 ECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGE 362
Query: 253 CCPTCLRQCLLWGNL 267
CCP C+ L N+
Sbjct: 363 CCPRCVSDPCLADNI 377
Score = 37.9 bits (84), Expect = 0.11
Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 12/126 (9%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRCSC-VHGEITC-RPVECDRAECKNPVLHPGECCP 255
C+C+ + +GT G + D + C+ H TC C L P C P
Sbjct: 193 CECRSGFHDDGTYSLSGESCI-DIDECALRTH---TCWNDSACINLAGGFDCLCP--CGP 246
Query: 256 TCLRQCLLWGNLYEHGERFAPKE--CAECVCHDGNMQCTRVDPELACPR--LPCDPPQQF 311
+C C G L +G+ + KE C+ C C DG + C R + P L C P
Sbjct: 247 SCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCPECDT 306
Query: 312 SVPGEC 317
V +C
Sbjct: 307 RVTSQC 312
>CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 115 bits (277), Expect = 5e-25
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C + C NL Y C C G++ G C D+DEC+ +C
Sbjct: 121 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRY------RYCQ 174
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN+ G + CQC G+ + +CV+V+EC+ G + C N+ G++ CRC
Sbjct: 175 H--RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECD---MGAPCEQRCFNSYGTFLCRCH 229
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE DG++C +DEC+ S+ C + RCVN G F C C
Sbjct: 230 QGYELHRDGFSCSDIDECSYSSYLCQY--RCVNEPGRFSCHC 269
Score = 113 bits (273), Expect = 1e-24
Identities = 88/284 (30%), Positives = 121/284 (42%), Gaps = 35/284 (12%)
Query: 213 DGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
DG W D C V+ +T P C + E K + G C R + +L+ G
Sbjct: 41 DGYEWDPDSQHCRDVNECLTI-PEAC-KGEMKCINHYGGYLCLP--RSAAVINDLHGEGP 96
Query: 273 ------RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVPGECCKFCPGVD 325
P C D C VD E A C P Q ++PG CP
Sbjct: 97 PPPVPPAQHPNPCPPGYEPDDQDSCVDVD-ECAQALHDCRPSQDCHNLPGSYQCTCPD-G 154
Query: 326 YCNMGHSC---DE------NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
Y +G C DE C+NL + C+C GFQ + +C DV+EC
Sbjct: 155 YRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM----- 209
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C RC N G ++C+C GY +D F+C ++DEC +++ C C N PG +
Sbjct: 210 GAPCEQ--RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRF 265
Query: 434 TCRCRDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+C C GY+ C +DEC G+H C + CVN GG+RC
Sbjct: 266 SCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 88.2 bits (209), Expect = 8e-17
Identities = 50/146 (34%), Positives = 68/146 (46%), Gaps = 17/146 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGL 359
R C+P Q G + C V+ C+MG C++ C N + C+C+QG++ DG
Sbjct: 185 RCQCEPGFQL---GPNNRSCVDVNECDMGAPCEQR--CFNSYGTFLCRCHQGYELHRDGF 239
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG 419
+C D+DEC + L C RCVN G + C C GY C ++DECE H
Sbjct: 240 SCSDIDECSYSSYL----CQY--RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQ 293
Query: 420 CHADAVCTNTPGSYTC----RCRDGY 441
C C N G Y C RC + Y
Sbjct: 294 CSEAQTCVNFHGGYRCVDTNRCVEPY 319
Score = 87.8 bits (208), Expect = 1e-16
Identities = 39/84 (46%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
C GY D+ +CV+VDEC H C C N PGSY C C DGY G C+ +DEC
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDEC 168
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
C H RCVN+ G FRC+C
Sbjct: 169 R--YRYCQH--RCVNLPGSFRCQC 188
>BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein.
Length = 363
Score = 115 bits (277), Expect = 5e-25
Identities = 59/163 (36%), Positives = 80/163 (49%), Gaps = 15/163 (9%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
VD C+ G C +A C N Y C C G++G+G C+D+DEC E +G H
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDEC-ENDYYNGGCVH--- 89
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N+ G Y C C G+ D NC++VDEC+ N GC +C N GSY C+C G+
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC--QQICVNAMGSYECQCHSGF 147
Query: 442 --EGDGYTCMHVD----ECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +TC+H C H C H R GG C+C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICR-ETPKGGVACDC 189
Score = 88.2 bits (209), Expect = 8e-17
Identities = 34/72 (47%), Positives = 43/72 (59%)
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
V+VDEC T CH DA+C NTP SY C C+ GY+G+G C +DEC + C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 468 VNIDGGFRCECF 479
+NI G +RC CF
Sbjct: 92 INIPGNYRCTCF 103
Score = 84.6 bits (200), Expect = 1e-15
Identities = 81/295 (27%), Positives = 121/295 (41%), Gaps = 42/295 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVE-C-DRAECKNPVLHPGECCPT 256
+C+ Y+ G VH RC+C G + C D EC++ + G C
Sbjct: 77 ECENDYYNGGCVHE--CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQD---NNGGCQQI 131
Query: 257 CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGE 316
C+ + H F C+ H N ++ + C + + P+ G
Sbjct: 132 CVNAMGSY-ECQCHSGFFLSDNQHTCI-HRSNEGMNCMNKDHGCAHICRETPKG----GV 185
Query: 317 CCKFCPGVDY----------CNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDV 364
C PG D CN G+ +++ C + +T C C+Q + DG TC +
Sbjct: 186 ACDCRPGFDLAQNQKDCTLTCNYGNGGCQHS-CEDTDTGPMCGCHQKYALHSDGRTC--I 242
Query: 365 DECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHAD 423
+ C G C + C + G C C G+T + D C +++EC N GC D
Sbjct: 243 ETCAVNNG----GC--DRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC--D 294
Query: 424 AVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C NT GS+ C CR GY+ D TC +DEC+ TC H C+N G F+C
Sbjct: 295 HFCRNTVGSFECGCRKGYKLLTDERTCQDIDECS-FERTCDHI--CINSPGSFQC 346
Score = 55.6 bits (128), Expect = 5e-07
Identities = 44/160 (27%), Positives = 58/160 (36%), Gaps = 18/160 (11%)
Query: 323 GVDYCNMGHSCDENATCMNL-NTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN 381
G++ N H C C C C GF Q+ +C C +
Sbjct: 163 GMNCMNKDHGCAH--ICRETPKGGVACDCRPGFD----LAQNQKDCTLTCNYGNGGCQHS 216
Query: 382 TRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
C + G +C C Y D C+E C N GC D C +T C C G
Sbjct: 217 --CEDTDTGPMCGCHQKYALHSDGRTCIET--CAVNNGGC--DRTCKDTATGVRCSCPVG 270
Query: 441 Y--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ + DG TC ++EC + C H C N G F C C
Sbjct: 271 FTLQPDGKTCKDINECLVNNGGCDHF--CRNTVGSFECGC 308
>BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein.
Length = 347
Score = 115 bits (277), Expect = 5e-25
Identities = 59/163 (36%), Positives = 80/163 (49%), Gaps = 15/163 (9%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
VD C+ G C +A C N Y C C G++G+G C+D+DEC E +G H
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDEC-ENDYYNGGCVH--- 89
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N+ G Y C C G+ D NC++VDEC+ N GC +C N GSY C+C G+
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC--QQICVNAMGSYECQCHSGF 147
Query: 442 --EGDGYTCMHVD----ECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +TC+H C H C H R GG C+C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICR-ETPKGGVACDC 189
Score = 88.2 bits (209), Expect = 8e-17
Identities = 34/72 (47%), Positives = 43/72 (59%)
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
V+VDEC T CH DA+C NTP SY C C+ GY+G+G C +DEC + C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 468 VNIDGGFRCECF 479
+NI G +RC CF
Sbjct: 92 INIPGNYRCTCF 103
Score = 45.2 bits (102), Expect = 7e-04
Identities = 44/189 (23%), Positives = 68/189 (35%), Gaps = 22/189 (11%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGF--QGDGLTC----QDVDECQEAGGL 373
C VD C + C + C+N Y C+C+ GF + TC + C
Sbjct: 115 CLDVDECQDNNGGCQQ--ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHG 172
Query: 374 HGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGS 432
H C + GG C C G+ +++ +C C GC C +T
Sbjct: 173 CAHICRETPK-----GGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHS--CEDTDTG 223
Query: 433 YTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQ 490
TC C Y DG TC+ DE + ++ ++D + E C ++
Sbjct: 224 PTCGCHQKYALHSDGRTCIEKDEAAI-ERSQFNATSVADVDKRVKRRLLMETCAVNNGGC 282
Query: 491 GRVVSEGAT 499
R + AT
Sbjct: 283 DRTCKDTAT 291
Score = 37.9 bits (84), Expect = 0.11
Identities = 41/185 (22%), Positives = 59/185 (31%), Gaps = 17/185 (9%)
Query: 281 ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCM 340
EC CH G D + C + + C C + C
Sbjct: 140 ECQCHSGFFLS---DNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLA 196
Query: 341 NLNTKYTCKCNQGFQGDGLTCQDVDE-----CQEAGGLH--GHHCHSNTRCVNVVGGYVC 393
T CN G G +C+D D C + LH G C +
Sbjct: 197 QNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIEKDEAAIERSQFNA 256
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTC--M 449
+ ++ K + ++ C N GC D C +T C C G+ + DG TC
Sbjct: 257 TSVADVDKRVKRRLL-METCAVNNGGC--DRTCKDTATGVRCSCPVGFTLQPDGKTCKGQ 313
Query: 450 HVDEC 454
HV+ C
Sbjct: 314 HVELC 318
>BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 115 bits (277), Expect = 5e-25
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C + C NL Y C C G++ G C D+DEC+ +C
Sbjct: 121 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRY------RYCQ 174
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN+ G + CQC G+ + +CV+V+EC+ G + C N+ G++ CRC
Sbjct: 175 H--RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECD---MGAPCEQRCFNSYGTFLCRCH 229
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE DG++C +DEC+ S+ C + RCVN G F C C
Sbjct: 230 QGYELHRDGFSCSDIDECSYSSYLCQY--RCVNEPGRFSCHC 269
Score = 113 bits (273), Expect = 1e-24
Identities = 88/284 (30%), Positives = 121/284 (42%), Gaps = 35/284 (12%)
Query: 213 DGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
DG W D C V+ +T P C + E K + G C R + +L+ G
Sbjct: 41 DGYEWDPDSQHCRDVNECLTI-PEAC-KGEMKCINHYGGYLCLP--RSAAVINDLHGEGP 96
Query: 273 ------RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVPGECCKFCPGVD 325
P C D C VD E A C P Q ++PG CP
Sbjct: 97 PPPVPPAQHPNPCPPGYEPDDQDSCVDVD-ECAQALHDCRPSQDCHNLPGSYQCTCPD-G 154
Query: 326 YCNMGHSC---DE------NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
Y +G C DE C+NL + C+C GFQ + +C DV+EC
Sbjct: 155 YRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM----- 209
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C RC N G ++C+C GY +D F+C ++DEC +++ C C N PG +
Sbjct: 210 GAPCEQ--RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRF 265
Query: 434 TCRCRDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+C C GY+ C +DEC G+H C + CVN GG+RC
Sbjct: 266 SCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 88.2 bits (209), Expect = 8e-17
Identities = 50/146 (34%), Positives = 68/146 (46%), Gaps = 17/146 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGL 359
R C+P Q G + C V+ C+MG C++ C N + C+C+QG++ DG
Sbjct: 185 RCQCEPGFQL---GPNNRSCVDVNECDMGAPCEQR--CFNSYGTFLCRCHQGYELHRDGF 239
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG 419
+C D+DEC + L C RCVN G + C C GY C ++DECE H
Sbjct: 240 SCSDIDECSYSSYL----CQY--RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQ 293
Query: 420 CHADAVCTNTPGSYTC----RCRDGY 441
C C N G Y C RC + Y
Sbjct: 294 CSEAQTCVNFHGGYRCVDTNRCVEPY 319
Score = 87.8 bits (208), Expect = 1e-16
Identities = 39/84 (46%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
C GY D+ +CV+VDEC H C C N PGSY C C DGY G C+ +DEC
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDEC 168
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
C H RCVN+ G FRC+C
Sbjct: 169 R--YRYCQH--RCVNLPGSFRCQC 188
>AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein.
Length = 443
Score = 115 bits (277), Expect = 5e-25
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C + C NL Y C C G++ G C D+DEC+ +C
Sbjct: 121 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRY------RYCQ 174
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN+ G + CQC G+ + +CV+V+EC+ G + C N+ G++ CRC
Sbjct: 175 H--RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECD---MGAPCEQRCFNSYGTFLCRCH 229
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE DG++C +DEC+ S+ C + RCVN G F C C
Sbjct: 230 QGYELHRDGFSCSDIDECSYSSYLCQY--RCVNEPGRFSCHC 269
Score = 113 bits (273), Expect = 1e-24
Identities = 88/284 (30%), Positives = 121/284 (42%), Gaps = 35/284 (12%)
Query: 213 DGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
DG W D C V+ +T P C + E K + G C R + +L+ G
Sbjct: 41 DGYEWDPDSQHCRDVNECLTI-PEAC-KGEMKCINHYGGYLCLP--RSAAVINDLHGEGP 96
Query: 273 ------RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVPGECCKFCPGVD 325
P C D C VD E A C P Q ++PG CP
Sbjct: 97 PPPVPPAQHPNPCPPGYEPDDQDSCVDVD-ECAQALHDCRPSQDCHNLPGSYQCTCPD-G 154
Query: 326 YCNMGHSC---DE------NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
Y +G C DE C+NL + C+C GFQ + +C DV+EC
Sbjct: 155 YRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM----- 209
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C RC N G ++C+C GY +D F+C ++DEC +++ C C N PG +
Sbjct: 210 GAPCEQ--RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRF 265
Query: 434 TCRCRDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+C C GY+ C +DEC G+H C + CVN GG+RC
Sbjct: 266 SCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 88.2 bits (209), Expect = 8e-17
Identities = 50/146 (34%), Positives = 68/146 (46%), Gaps = 17/146 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGL 359
R C+P Q G + C V+ C+MG C++ C N + C+C+QG++ DG
Sbjct: 185 RCQCEPGFQL---GPNNRSCVDVNECDMGAPCEQR--CFNSYGTFLCRCHQGYELHRDGF 239
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG 419
+C D+DEC + L C RCVN G + C C GY C ++DECE H
Sbjct: 240 SCSDIDECSYSSYL----CQY--RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQ 293
Query: 420 CHADAVCTNTPGSYTC----RCRDGY 441
C C N G Y C RC + Y
Sbjct: 294 CSEAQTCVNFHGGYRCVDTNRCVEPY 319
Score = 87.8 bits (208), Expect = 1e-16
Identities = 39/84 (46%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
C GY D+ +CV+VDEC H C C N PGSY C C DGY G C+ +DEC
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDEC 168
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
C H RCVN+ G FRC+C
Sbjct: 169 R--YRYCQH--RCVNLPGSFRCQC 188
>AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein.
Length = 443
Score = 115 bits (277), Expect = 5e-25
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C + C NL Y C C G++ G C D+DEC+ +C
Sbjct: 121 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRY------RYCQ 174
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN+ G + CQC G+ + +CV+V+EC+ G + C N+ G++ CRC
Sbjct: 175 H--RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECD---MGAPCEQRCFNSYGTFLCRCH 229
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE DG++C +DEC+ S+ C + RCVN G F C C
Sbjct: 230 QGYELHRDGFSCSDIDECSYSSYLCQY--RCVNEPGRFSCHC 269
Score = 113 bits (273), Expect = 1e-24
Identities = 88/284 (30%), Positives = 121/284 (42%), Gaps = 35/284 (12%)
Query: 213 DGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
DG W D C V+ +T P C + E K + G C R + +L+ G
Sbjct: 41 DGYEWDPDSQHCRDVNECLTI-PEAC-KGEMKCINHYGGYLCLP--RSAAVINDLHGEGP 96
Query: 273 ------RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVPGECCKFCPGVD 325
P C D C VD E A C P Q ++PG CP
Sbjct: 97 PPPVPPAQHPNPCPPGYEPDDQDSCVDVD-ECAQALHDCRPSQDCHNLPGSYQCTCPD-G 154
Query: 326 YCNMGHSC---DE------NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
Y +G C DE C+NL + C+C GFQ + +C DV+EC
Sbjct: 155 YRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM----- 209
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C RC N G ++C+C GY +D F+C ++DEC +++ C C N PG +
Sbjct: 210 GAPCEQ--RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRF 265
Query: 434 TCRCRDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+C C GY+ C +DEC G+H C + CVN GG+RC
Sbjct: 266 SCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 88.2 bits (209), Expect = 8e-17
Identities = 50/146 (34%), Positives = 68/146 (46%), Gaps = 17/146 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGL 359
R C+P Q G + C V+ C+MG C++ C N + C+C+QG++ DG
Sbjct: 185 RCQCEPGFQL---GPNNRSCVDVNECDMGAPCEQR--CFNSYGTFLCRCHQGYELHRDGF 239
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG 419
+C D+DEC + L C RCVN G + C C GY C ++DECE H
Sbjct: 240 SCSDIDECSYSSYL----CQY--RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQ 293
Query: 420 CHADAVCTNTPGSYTC----RCRDGY 441
C C N G Y C RC + Y
Sbjct: 294 CSEAQTCVNFHGGYRCVDTNRCVEPY 319
Score = 87.8 bits (208), Expect = 1e-16
Identities = 39/84 (46%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
C GY D+ +CV+VDEC H C C N PGSY C C DGY G C+ +DEC
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDEC 168
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
C H RCVN+ G FRC+C
Sbjct: 169 R--YRYCQH--RCVNLPGSFRCQC 188
>AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing
fibulin-like extracellular matrix protein 2 protein.
Length = 443
Score = 115 bits (277), Expect = 5e-25
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C + C NL Y C C G++ G C D+DEC+ +C
Sbjct: 121 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRY------RYCQ 174
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN+ G + CQC G+ + +CV+V+EC+ G + C N+ G++ CRC
Sbjct: 175 H--RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECD---MGAPCEQRCFNSYGTFLCRCH 229
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE DG++C +DEC+ S+ C + RCVN G F C C
Sbjct: 230 QGYELHRDGFSCSDIDECSYSSYLCQY--RCVNEPGRFSCHC 269
Score = 113 bits (273), Expect = 1e-24
Identities = 88/284 (30%), Positives = 121/284 (42%), Gaps = 35/284 (12%)
Query: 213 DGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
DG W D C V+ +T P C + E K + G C R + +L+ G
Sbjct: 41 DGYEWDPDSQHCRDVNECLTI-PEAC-KGEMKCINHYGGYLCLP--RSAAVINDLHGEGP 96
Query: 273 ------RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVPGECCKFCPGVD 325
P C D C VD E A C P Q ++PG CP
Sbjct: 97 PPPVPPAQHPNPCPPGYEPDDQDSCVDVD-ECAQALHDCRPSQDCHNLPGSYQCTCPD-G 154
Query: 326 YCNMGHSC---DE------NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
Y +G C DE C+NL + C+C GFQ + +C DV+EC
Sbjct: 155 YRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM----- 209
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C RC N G ++C+C GY +D F+C ++DEC +++ C C N PG +
Sbjct: 210 GAPCEQ--RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRF 265
Query: 434 TCRCRDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+C C GY+ C +DEC G+H C + CVN GG+RC
Sbjct: 266 SCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 88.2 bits (209), Expect = 8e-17
Identities = 50/146 (34%), Positives = 68/146 (46%), Gaps = 17/146 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGL 359
R C+P Q G + C V+ C+MG C++ C N + C+C+QG++ DG
Sbjct: 185 RCQCEPGFQL---GPNNRSCVDVNECDMGAPCEQR--CFNSYGTFLCRCHQGYELHRDGF 239
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG 419
+C D+DEC + L C RCVN G + C C GY C ++DECE H
Sbjct: 240 SCSDIDECSYSSYL----CQY--RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQ 293
Query: 420 CHADAVCTNTPGSYTC----RCRDGY 441
C C N G Y C RC + Y
Sbjct: 294 CSEAQTCVNFHGGYRCVDTNRCVEPY 319
Score = 87.8 bits (208), Expect = 1e-16
Identities = 39/84 (46%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
C GY D+ +CV+VDEC H C C N PGSY C C DGY G C+ +DEC
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDEC 168
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
C H RCVN+ G FRC+C
Sbjct: 169 R--YRYCQH--RCVNLPGSFRCQC 188
>AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein.
Length = 439
Score = 115 bits (277), Expect = 5e-25
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C + C NL Y C C G++ G C D+DEC+ +C
Sbjct: 117 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRY------RYCQ 170
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN+ G + CQC G+ + +CV+V+EC+ G + C N+ G++ CRC
Sbjct: 171 H--RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECD---MGAPCEQRCFNSYGTFLCRCH 225
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE DG++C +DEC+ S+ C + RCVN G F C C
Sbjct: 226 QGYELHRDGFSCSDIDECSYSSYLCQY--RCVNEPGRFSCHC 265
Score = 107 bits (256), Expect = 2e-22
Identities = 69/205 (33%), Positives = 95/205 (46%), Gaps = 25/205 (12%)
Query: 286 DGNMQCTRVDPELACPRLPCDPPQQ-FSVPGECCKFCPGVDYCNMGHSC---DE------ 335
D C VD E A C P Q ++PG CP Y +G C DE
Sbjct: 112 DDQDSCVDVD-ECAQALHDCRPSQDCHNLPGSYQCTCPD-GYRKIGPECVDIDECRYRYC 169
Query: 336 NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C+NL + C+C GFQ + +C DV+EC G C RC N G ++C
Sbjct: 170 QHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM-----GAPCEQ--RCFNSYGTFLC 222
Query: 394 QCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT-CMHV 451
+C GY +D F+C ++DEC +++ C C N PG ++C C GY+ C +
Sbjct: 223 RCHQGYELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHCPQGYQLLATRLCQDI 280
Query: 452 DECTEGSHTCHHSARCVNIDGGFRC 476
DEC G+H + CVN GG+RC
Sbjct: 281 DECESGAHQWSEAQTCVNFHGGYRC 305
Score = 86.2 bits (204), Expect = 3e-16
Identities = 38/81 (46%), Positives = 45/81 (55%), Gaps = 4/81 (4%)
Query: 398 GYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEG 457
GY D+ +CV+VDEC H C C N PGSY C C DGY G C+ +DEC
Sbjct: 108 GYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECR-- 165
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
C H RCVN+ G FRC+C
Sbjct: 166 YRYCQH--RCVNLPGSFRCQC 184
Score = 83.8 bits (198), Expect = 2e-15
Identities = 49/146 (33%), Positives = 67/146 (45%), Gaps = 17/146 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGL 359
R C+P Q G + C V+ C+MG C++ C N + C+C+QG++ DG
Sbjct: 181 RCQCEPGFQL---GPNNRSCVDVNECDMGAPCEQR--CFNSYGTFLCRCHQGYELHRDGF 235
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG 419
+C D+DEC + L C RCVN G + C C GY C ++DECE H
Sbjct: 236 SCSDIDECSYSSYL----CQY--RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQ 289
Query: 420 CHADAVCTNTPGSYTC----RCRDGY 441
C N G Y C RC + Y
Sbjct: 290 WSEAQTCVNFHGGYRCVDTNRCVEPY 315
Score = 48.4 bits (110), Expect = 8e-05
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 29/112 (25%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD-------------- 439
+C GYT+ NC +V+EC C + C N G Y C R
Sbjct: 38 ECTDGYTQTA--NCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPP 95
Query: 440 ------------GYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE D +C+ VDEC + H C S C N+ G ++C C
Sbjct: 96 PVPPVNTQPLPTGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTC 147
Score = 37.5 bits (83), Expect = 0.15
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
P SYT C DGY C V+EC C +C+N GG+ C
Sbjct: 33 PDSYT-ECTDGYTQTA-NCRDVNECLTIPEACKGEMKCINHYGGYLC 77
>AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming growth
factor-beta binding protein 4L protein.
Length = 1624
Score = 115 bits (277), Expect = 5e-25
Identities = 98/274 (35%), Positives = 115/274 (41%), Gaps = 32/274 (11%)
Query: 223 RCSCVHG--EITCRPVEC-DRAEC-KNPVLHP-GECCPTCLRQCLLWGNLYEHGERFAP- 276
RCSC G + RP C D EC + P GEC T Y G R A
Sbjct: 859 RCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 918
Query: 277 ---KECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN-MGH 331
EC+E +C G CT D C C P + G C VD C G
Sbjct: 919 LDVDECSEEDLCQSGI--CTNTDGSFECI---CPPGHR---AGPDLASCLDVDECRERGP 970
Query: 332 SCDENATCMNLNTKYTC--KCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
+ + C N Y C C+ G+ G TC DVDECQE +G RC N
Sbjct: 971 ALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQE----YGPEICGAQRCENTP 1026
Query: 389 GGYVCQ--CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--D 444
G Y C C GY C +VDEC N C A AVC N PGS+ C C GYEG D
Sbjct: 1027 GSYRCTPACDPGYQPTPGGGCQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARD 1085
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G C+ V+EC C +A C N++G F C C
Sbjct: 1086 GRHCVDVNECETLQGVC-GAALCENVEGSFLCVC 1118
Score = 101 bits (241), Expect = 1e-20
Identities = 79/257 (30%), Positives = 96/257 (37%), Gaps = 33/257 (12%)
Query: 230 EITCRPVECDRAECKNPVLHPGE--C-CPTCLRQCLLWGNLYEHGERFAPKECAECVCHD 286
E T P C R CKN PG C CP R ++ E + P C
Sbjct: 674 ECTQSPGLCGRGACKNL---PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA 730
Query: 287 GNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKY 346
G+ C ACP + PG C+ VD C C N +
Sbjct: 731 GSFHC-------ACPA-----GFRSRGPGAPCQ---DVDECARSPPPCTYGRCENTEGSF 775
Query: 347 TCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK 404
C C GFQ + G C+DVDEC+ H CVN G + C+ +
Sbjct: 776 QCVCPMGFQPNAAGSECEDVDECEN------HLACPGQECVNSPGSFQCRACPSGHHLHR 829
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EGDGYTCMHVDECTEGSHTC 461
C +VDEC C CTNT GS+ C C GY G C V+EC EG C
Sbjct: 830 GRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDF-C 888
Query: 462 HHSARCVNIDGGFRCEC 478
C+N DG F C C
Sbjct: 889 FPHGECLNTDGSFACTC 905
Score = 96.3 bits (229), Expect = 3e-19
Identities = 63/192 (32%), Positives = 81/192 (42%), Gaps = 20/192 (10%)
Query: 293 RVDPELACPRLPCDPPQQFSVPGECCKFCP-GVDYCNMGHSCDENATCMNLNTKYTCKCN 351
R PE P +P + G C C G C++ + YTC C+
Sbjct: 521 RPGPEFPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGR-------CISRPSGYTCACD 573
Query: 352 QGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-NCV 408
GF+ G C DVDEC+ C RC N G + C C G+ + C+
Sbjct: 574 SGFRLSPQGTRCIDVDECRRVPP----PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECL 628
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMHVDECTEGSHTCHHSAR 466
+VDEC C C NTPGS+ C C GY+ G +C VDECT+ C A
Sbjct: 629 DVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA- 686
Query: 467 CVNIDGGFRCEC 478
C N+ G FRC C
Sbjct: 687 CKNLPGSFRCVC 698
Score = 89.8 bits (213), Expect = 3e-17
Identities = 87/290 (30%), Positives = 112/290 (38%), Gaps = 37/290 (12%)
Query: 204 CYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAECKN--PVLHPGEC--CPT 256
C N V G R C+C G ++ + C D EC+ P PG C P
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 257 CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPEL---ACPRLP----CDPPQ 309
R C+ G R P+ AEC+ D +C RV P C P C P
Sbjct: 609 SFR-CVCGP-----GFRAGPR-AAECLDVD---ECHRVPPPCDLGRCENTPGSFLCVCPA 658
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
+ C VD C C NL + C C GF+G +DVDEC +
Sbjct: 659 GYQAAPHGAS-CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE-EDVDECAQ 716
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
G RC N G + C C G+ +R C +VDEC + C C N
Sbjct: 717 EPPPCG-----PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC-TYGRCEN 770
Query: 429 TPGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
T GS+ C C G++ + G C VDEC +H CVN G F+C
Sbjct: 771 TEGSFQCVCPMGFQPNAAGSECEDVDECE--NHLACPGQECVNSPGSFQC 818
Score = 73.3 bits (172), Expect = 2e-12
Identities = 53/161 (32%), Positives = 69/161 (42%), Gaps = 16/161 (9%)
Query: 287 GNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN-MGHSCDENATCMNLNTK 345
G+ +C C R CDP G C VD C G C N
Sbjct: 974 GSQRCENSPGSYRCVR-DCDPGYHAGPEGTC----DDVDECQEYGPEICGAQRCENTPGS 1028
Query: 346 YTCK--CNQGFQGD-GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-R 401
Y C C+ G+Q G CQDVDEC+ C ++ C N+ G + C C GY
Sbjct: 1029 YRCTPACDPGYQPTPGGGCQDVDECRNRS-----FCGAHAVCQNLPGSFQCLCDQGYEGA 1083
Query: 402 KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
+D +CV+V+ECE C A A+C N GS+ C C + E
Sbjct: 1084 RDGRHCVDVNECETLQGVCGA-ALCENVEGSFLCVCPNSPE 1123
Score = 58.8 bits (136), Expect = 6e-08
Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 8/76 (10%)
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GYTCMHVDECTE---GSHTCH 462
+E +EC G GC + C P +TCRC DGY D C+ ++EC E S C
Sbjct: 1532 LEAEEC-GILDGC-TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC- 1588
Query: 463 HSARCVNIDGGFRCEC 478
+ARC+N DG FRC C
Sbjct: 1589 VNARCLNTDGSFRCIC 1604
Score = 58.4 bits (135), Expect = 7e-08
Identities = 34/91 (37%), Positives = 38/91 (41%), Gaps = 6/91 (6%)
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDECE 414
GD +DVDECQ C S CVN GY C C G Y + C++ DEC
Sbjct: 1246 GDLSLRRDVDECQL---FRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECA 1301
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
C C NT GSY C C DG
Sbjct: 1302 DEEPACEGGR-CVNTVGSYHCTCEPPLVLDG 1331
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 10/81 (12%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD--KFNCVEVDEC---EGNTHGC 420
E +E G L G C +N RCV V G+ C+C GY R D + CV+++EC E + C
Sbjct: 1533 EAEECGILDG--C-TNGRCVRVPEGFTCRCFDGY-RLDMTRMACVDINECDEAEAASPLC 1588
Query: 421 HADAVCTNTPGSYTCRCRDGY 441
+A C NT GS+ C CR G+
Sbjct: 1589 -VNARCLNTDGSFRCICRPGF 1608
Score = 52.0 bits (119), Expect = 6e-06
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEGSHTCHHSAR 466
+VDEC+ VC NT Y+C C +G Y C+ DEC + C R
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPAC-EGGR 1311
Query: 467 CVNIDGGFRCEC 478
CVN G + C C
Sbjct: 1312 CVNTVGSYHCTC 1323
Score = 47.2 bits (107), Expect = 2e-04
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
Query: 304 PCDPPQQFSVPGECCKFCPGVDY--CNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GL 359
P +PP+ S G + ++ C + C N C+ + +TC+C G++ D +
Sbjct: 1512 PEEPPEGGSYAGSLAEPYEELEAEECGILDGCT-NGRCVRVPEGFTCRCFDGYRLDMTRM 1570
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY 399
C D++EC EA C N RC+N G + C C G+
Sbjct: 1571 ACVDINECDEAEAA-SPLC-VNARCLNTDGSFRCICRPGF 1608
Score = 41.5 bits (93), Expect = 0.009
Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 324 VDYCNMGHS--CDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHCH 379
VD C + C ++ C+N Y+C C+ G + L C D DEC + C
Sbjct: 1254 VDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD----EEPACE 1308
Query: 380 SNTRCVNVVGGYVCQC 395
RCVN VG Y C C
Sbjct: 1309 GG-RCVNTVGSYHCTC 1323
Score = 41.1 bits (92), Expect = 0.012
Identities = 39/125 (31%), Positives = 53/125 (42%), Gaps = 20/125 (16%)
Query: 358 GLTCQDVDECQEAGGLHG-HHCH------SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEV 410
GL Q+V C+ AG G H C N+ V+ G C G+ R + +C +V
Sbjct: 304 GLRTQEVC-CRGAGLAWGVHDCQLCSERLGNSERVSAPDG---PCPTGFERVNG-SCEDV 358
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCV 468
DEC H + C NT G YTC C DG+ + +C+ +E C R
Sbjct: 359 DECATGGRCQHGE--CANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLR-- 414
Query: 469 NIDGG 473
DGG
Sbjct: 415 --DGG 417
Score = 39.5 bits (88), Expect = 0.037
Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 10/82 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCV 408
C GF+ +C+DVDEC G C + C N GGY C C G+ + +C+
Sbjct: 344 CPTGFERVNGSCEDVDECATGG-----RC-QHGECANTRGGYTCVCPDGFLLDSSRSSCI 397
Query: 409 E---VDECEGNTHGCHADAVCT 427
+ E +G D C+
Sbjct: 398 SQHVISEAKGPCFRVLRDGGCS 419
Score = 38.3 bits (85), Expect = 0.084
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 437 CRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G+E +C VDEC G C H C N GG+ C C
Sbjct: 344 CPTGFERVNGSCEDVDECATGGR-CQHG-ECANTRGGYTCVC 383
Score = 32.7 bits (71), Expect = 4.2
Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
C VD C G C ++ C N YTC C GF
Sbjct: 355 CEDVDECATGGRC-QHGECANTRGGYTCVCPDGF 387
>AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming growth
factor-beta binding protein 4S protein.
Length = 1557
Score = 115 bits (277), Expect = 5e-25
Identities = 98/274 (35%), Positives = 115/274 (41%), Gaps = 32/274 (11%)
Query: 223 RCSCVHG--EITCRPVEC-DRAEC-KNPVLHP-GECCPTCLRQCLLWGNLYEHGERFAP- 276
RCSC G + RP C D EC + P GEC T Y G R A
Sbjct: 792 RCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 851
Query: 277 ---KECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN-MGH 331
EC+E +C G CT D C C P + G C VD C G
Sbjct: 852 LDVDECSEEDLCQSGI--CTNTDGSFECI---CPPGHR---AGPDLASCLDVDECRERGP 903
Query: 332 SCDENATCMNLNTKYTC--KCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
+ + C N Y C C+ G+ G TC DVDECQE +G RC N
Sbjct: 904 ALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQE----YGPEICGAQRCENTP 959
Query: 389 GGYVCQ--CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--D 444
G Y C C GY C +VDEC N C A AVC N PGS+ C C GYEG D
Sbjct: 960 GSYRCTPACDPGYQPTPGGGCQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARD 1018
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G C+ V+EC C +A C N++G F C C
Sbjct: 1019 GRHCVDVNECETLQGVC-GAALCENVEGSFLCVC 1051
Score = 101 bits (241), Expect = 1e-20
Identities = 79/257 (30%), Positives = 96/257 (37%), Gaps = 33/257 (12%)
Query: 230 EITCRPVECDRAECKNPVLHPGE--C-CPTCLRQCLLWGNLYEHGERFAPKECAECVCHD 286
E T P C R CKN PG C CP R ++ E + P C
Sbjct: 607 ECTQSPGLCGRGACKNL---PGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTA 663
Query: 287 GNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKY 346
G+ C ACP + PG C+ VD C C N +
Sbjct: 664 GSFHC-------ACPA-----GFRSRGPGAPCQ---DVDECARSPPPCTYGRCENTEGSF 708
Query: 347 TCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK 404
C C GFQ + G C+DVDEC+ H CVN G + C+ +
Sbjct: 709 QCVCPMGFQPNAAGSECEDVDECEN------HLACPGQECVNSPGSFQCRACPSGHHLHR 762
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EGDGYTCMHVDECTEGSHTC 461
C +VDEC C CTNT GS+ C C GY G C V+EC EG C
Sbjct: 763 GRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDF-C 821
Query: 462 HHSARCVNIDGGFRCEC 478
C+N DG F C C
Sbjct: 822 FPHGECLNTDGSFACTC 838
Score = 96.3 bits (229), Expect = 3e-19
Identities = 63/192 (32%), Positives = 81/192 (42%), Gaps = 20/192 (10%)
Query: 293 RVDPELACPRLPCDPPQQFSVPGECCKFCP-GVDYCNMGHSCDENATCMNLNTKYTCKCN 351
R PE P +P + G C C G C++ + YTC C+
Sbjct: 454 RPGPEFPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGR-------CISRPSGYTCACD 506
Query: 352 QGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-NCV 408
GF+ G C DVDEC+ C RC N G + C C G+ + C+
Sbjct: 507 SGFRLSPQGTRCIDVDECRRVPP----PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECL 561
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMHVDECTEGSHTCHHSAR 466
+VDEC C C NTPGS+ C C GY+ G +C VDECT+ C A
Sbjct: 562 DVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA- 619
Query: 467 CVNIDGGFRCEC 478
C N+ G FRC C
Sbjct: 620 CKNLPGSFRCVC 631
Score = 89.8 bits (213), Expect = 3e-17
Identities = 87/290 (30%), Positives = 112/290 (38%), Gaps = 37/290 (12%)
Query: 204 CYSNGTVHADGATWQRDCN-RCSCVHG-EITCRPVEC-DRAECKN--PVLHPGEC--CPT 256
C N V G R C+C G ++ + C D EC+ P PG C P
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 257 CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPEL---ACPRLP----CDPPQ 309
R C+ G R P+ AEC+ D +C RV P C P C P
Sbjct: 542 SFR-CVCGP-----GFRAGPR-AAECLDVD---ECHRVPPPCDLGRCENTPGSFLCVCPA 591
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
+ C VD C C NL + C C GF+G +DVDEC +
Sbjct: 592 GYQAAPHGAS-CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE-EDVDECAQ 649
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
G RC N G + C C G+ +R C +VDEC + C C N
Sbjct: 650 EPPPCG-----PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC-TYGRCEN 703
Query: 429 TPGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
T GS+ C C G++ + G C VDEC +H CVN G F+C
Sbjct: 704 TEGSFQCVCPMGFQPNAAGSECEDVDECE--NHLACPGQECVNSPGSFQC 751
Score = 73.3 bits (172), Expect = 2e-12
Identities = 53/161 (32%), Positives = 69/161 (42%), Gaps = 16/161 (9%)
Query: 287 GNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN-MGHSCDENATCMNLNTK 345
G+ +C C R CDP G C VD C G C N
Sbjct: 907 GSQRCENSPGSYRCVR-DCDPGYHAGPEGTC----DDVDECQEYGPEICGAQRCENTPGS 961
Query: 346 YTCK--CNQGFQGD-GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-R 401
Y C C+ G+Q G CQDVDEC+ C ++ C N+ G + C C GY
Sbjct: 962 YRCTPACDPGYQPTPGGGCQDVDECRNRS-----FCGAHAVCQNLPGSFQCLCDQGYEGA 1016
Query: 402 KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
+D +CV+V+ECE C A A+C N GS+ C C + E
Sbjct: 1017 RDGRHCVDVNECETLQGVCGA-ALCENVEGSFLCVCPNSPE 1056
Score = 58.8 bits (136), Expect = 6e-08
Identities = 32/76 (42%), Positives = 41/76 (53%), Gaps = 8/76 (10%)
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GYTCMHVDECTE---GSHTCH 462
+E +EC G GC + C P +TCRC DGY D C+ ++EC E S C
Sbjct: 1465 LEAEEC-GILDGC-TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC- 1521
Query: 463 HSARCVNIDGGFRCEC 478
+ARC+N DG FRC C
Sbjct: 1522 VNARCLNTDGSFRCIC 1537
Score = 58.4 bits (135), Expect = 7e-08
Identities = 34/91 (37%), Positives = 38/91 (41%), Gaps = 6/91 (6%)
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDECE 414
GD +DVDECQ C S CVN GY C C G Y + C++ DEC
Sbjct: 1179 GDLSLRRDVDECQL---FRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECA 1234
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
C C NT GSY C C DG
Sbjct: 1235 DEEPACEGGR-CVNTVGSYHCTCEPPLVLDG 1264
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/81 (41%), Positives = 46/81 (56%), Gaps = 10/81 (12%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD--KFNCVEVDEC---EGNTHGC 420
E +E G L G C +N RCV V G+ C+C GY R D + CV+++EC E + C
Sbjct: 1466 EAEECGILDG--C-TNGRCVRVPEGFTCRCFDGY-RLDMTRMACVDINECDEAEAASPLC 1521
Query: 421 HADAVCTNTPGSYTCRCRDGY 441
+A C NT GS+ C CR G+
Sbjct: 1522 -VNARCLNTDGSFRCICRPGF 1541
Score = 52.0 bits (119), Expect = 6e-06
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEGSHTCHHSAR 466
+VDEC+ VC NT Y+C C +G Y C+ DEC + C R
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPAC-EGGR 1244
Query: 467 CVNIDGGFRCEC 478
CVN G + C C
Sbjct: 1245 CVNTVGSYHCTC 1256
Score = 47.2 bits (107), Expect = 2e-04
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
Query: 304 PCDPPQQFSVPGECCKFCPGVDY--CNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GL 359
P +PP+ S G + ++ C + C N C+ + +TC+C G++ D +
Sbjct: 1445 PEEPPEGGSYAGSLAEPYEELEAEECGILDGCT-NGRCVRVPEGFTCRCFDGYRLDMTRM 1503
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY 399
C D++EC EA C N RC+N G + C C G+
Sbjct: 1504 ACVDINECDEAEAA-SPLC-VNARCLNTDGSFRCICRPGF 1541
Score = 41.5 bits (93), Expect = 0.009
Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 324 VDYCNMGHS--CDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHCH 379
VD C + C ++ C+N Y+C C+ G + L C D DEC + C
Sbjct: 1187 VDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD----EEPACE 1241
Query: 380 SNTRCVNVVGGYVCQC 395
RCVN VG Y C C
Sbjct: 1242 GG-RCVNTVGSYHCTC 1256
Score = 41.1 bits (92), Expect = 0.012
Identities = 39/125 (31%), Positives = 53/125 (42%), Gaps = 20/125 (16%)
Query: 358 GLTCQDVDECQEAGGLHG-HHCH------SNTRCVNVVGGYVCQCLGGYTRKDKFNCVEV 410
GL Q+V C+ AG G H C N+ V+ G C G+ R + +C +V
Sbjct: 237 GLRTQEVC-CRGAGLAWGVHDCQLCSERLGNSERVSAPDG---PCPTGFERVNG-SCEDV 291
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCV 468
DEC H + C NT G YTC C DG+ + +C+ +E C R
Sbjct: 292 DECATGGRCQHGE--CANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLR-- 347
Query: 469 NIDGG 473
DGG
Sbjct: 348 --DGG 350
Score = 39.5 bits (88), Expect = 0.037
Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 10/82 (12%)
Query: 350 CNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCV 408
C GF+ +C+DVDEC G C + C N GGY C C G+ + +C+
Sbjct: 277 CPTGFERVNGSCEDVDECATGG-----RC-QHGECANTRGGYTCVCPDGFLLDSSRSSCI 330
Query: 409 E---VDECEGNTHGCHADAVCT 427
+ E +G D C+
Sbjct: 331 SQHVISEAKGPCFRVLRDGGCS 352
Score = 38.3 bits (85), Expect = 0.084
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 437 CRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G+E +C VDEC G C H C N GG+ C C
Sbjct: 277 CPTGFERVNGSCEDVDECATGGR-CQHG-ECANTRGGYTCVC 316
Score = 32.7 bits (71), Expect = 4.2
Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
C VD C G C ++ C N YTC C GF
Sbjct: 288 CEDVDECATGGRC-QHGECANTRGGYTCVCPDGF 320
>AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein.
Length = 1365
Score = 115 bits (277), Expect = 5e-25
Identities = 78/247 (31%), Positives = 109/247 (44%), Gaps = 34/247 (13%)
Query: 258 LRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCTRVDPELACPRLPCDPPQQF 311
+ +C + +L HG+ +C C G CT +D P L C Q
Sbjct: 1029 INECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL-CGRGQCV 1087
Query: 312 SVPG--EC-C-----------KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ-- 355
+ PG EC C K C +D C C N Y C+C G Q
Sbjct: 1088 NTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLS 1147
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECE 414
+ C D++EC+ L H C N RCVN++G Y C C GY + D+ CV++DEC
Sbjct: 1148 PNISACIDINECE----LSAHLC-PNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECS 1202
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDG 472
GC + CTN+ GSY C C+ G+ D +C +DEC + + C +C NI G
Sbjct: 1203 IMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC-DGGQCTNIPG 1259
Query: 473 GFRCECF 479
+RC C+
Sbjct: 1260 EYRCLCY 1266
Score = 113 bits (273), Expect = 1e-24
Identities = 60/165 (36%), Positives = 81/165 (49%), Gaps = 14/165 (8%)
Query: 320 FCPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
FC +D C+ M C+ C N Y C C GF D +C D+DEC++ +
Sbjct: 1194 FCVDIDECSIMNGGCE--TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNI--- 1248
Query: 377 HCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C +C N+ G Y C C G+ +D CV+V+EC+ N + C C NT GS+ C
Sbjct: 1249 -CDGG-QCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNIC-LSGTCENTKGSFIC 1305
Query: 436 RCRDGYEGD-GYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C GY G G T C ++EC G+H C A C N G F+C C
Sbjct: 1306 HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSC 1350
Score = 111 bits (267), Expect = 7e-24
Identities = 75/240 (31%), Positives = 108/240 (45%), Gaps = 21/240 (8%)
Query: 223 RCSCVHG-EITCRPVEC-DRAECK-NPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPK 277
RC C G +++ C D EC+ + L P C + QC + +R
Sbjct: 1137 RCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Query: 278 ECAECVCHDGNMQ--CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
+ EC +G + CT + C C P +P + + C +D C + +
Sbjct: 1197 DIDECSIMNGGCETFCTNSEGSYECS---CQPGFAL-MPDQ--RSCTDIDECEDNPNICD 1250
Query: 336 NATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N+ +Y C C GF D TC DV+EC L+ + C S T C N G ++C
Sbjct: 1251 GGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECD----LNPNICLSGT-CENTKGSFIC 1305
Query: 394 QCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVD 452
C GY+ +K K C +++ECE H C AVCTNT GS+ C C G+ GDG C +D
Sbjct: 1306 HCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLD 1365
Score = 111 bits (266), Expect = 1e-23
Identities = 66/184 (35%), Positives = 94/184 (51%), Gaps = 22/184 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT- 360
R C+ Q + GEC VD C + C C+N YTC+C G+Q LT
Sbjct: 473 RCECNKGFQLDLRGECID----VDECEK-NPC-AGGECINNQGSYTCQCRAGYQST-LTR 525
Query: 361 --CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNT 417
C+D+DEC + G + C+ N RC+N G + C C G+ +D NC ++DEC +
Sbjct: 526 TECRDIDECLQNGRI----CN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC--SI 578
Query: 418 HGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
+ +C N GS+ C C+ G++ DG C ++EC E C + RCVN DG +R
Sbjct: 579 RNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINEC-ETPGICMNG-RCVNTDGSYR 636
Query: 476 CECF 479
CECF
Sbjct: 637 CECF 640
Score = 103 bits (247), Expect = 2e-21
Identities = 68/214 (31%), Positives = 103/214 (48%), Gaps = 22/214 (10%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG 330
G + +EC EC M+ T EL CPR P ++ + G+ F ++ C M
Sbjct: 985 GAAWGTEECEECP-----MRNTPEYEEL-CPRGPGFATKEIT-NGK--PFFKDINECKMI 1035
Query: 331 HSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
S + C N + C+C+ GF D C D+DEC+ + L G +CVN
Sbjct: 1036 PSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCG-----RGQCVNTP 1090
Query: 389 GGYVCQCLGGYTRKDKF--NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GD 444
G + C+C GY NC+++DEC+ + C VC NT GSY C C G++ +
Sbjct: 1091 GDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG-GVCHNTEGSYRCECPPGHQLSPN 1149
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+ ++EC +H C + RCVN+ G ++C C
Sbjct: 1150 ISACIDINECELSAHLC-PNGRCVNLIGKYQCAC 1182
Score = 100 bits (240), Expect = 1e-20
Identities = 63/186 (33%), Positives = 92/186 (49%), Gaps = 18/186 (9%)
Query: 301 PRLPCD-PPQQFSVPG-ECCKFCPG--VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG 356
P++P PP ++ P E + P DYC + +N C+ C+CN+GFQ
Sbjct: 423 PQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQL 482
Query: 357 D-GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECE 414
D C DVDEC++ + C + C+N G Y CQC GY + + C ++DEC
Sbjct: 483 DLRGECIDVDECEK------NPC-AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECL 535
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDG 472
N C+ + C NT GS+ C C G+ DG C +DEC+ + C + C+N DG
Sbjct: 536 QNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSI-RNMC-LNGMCINEDG 592
Query: 473 GFRCEC 478
F+C C
Sbjct: 593 SFKCIC 598
Score = 81.8 bits (193), Expect = 7e-15
Identities = 59/170 (34%), Positives = 78/170 (45%), Gaps = 18/170 (10%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHG 375
ECC C +Y G C + N + +Y C+ G G D++EC L
Sbjct: 682 ECC--CASTEYA-FGEPC-QPCPAQN-SAEYQALCSSG-PGMTSAGSDINEC----ALDP 731
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
C N C N+ G Y C C GY NCV+++EC N+ C + C NTPGS+
Sbjct: 732 DIC-PNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCD-NGQCRNTPGSFV 789
Query: 435 CRCRDG--YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTEN 482
C C G Y+ D TC +DEC S C + C N G F CEC +E+
Sbjct: 790 CTCPKGFIYKPDLKTCEDIDECE--SSPCINGV-CKNSPGSFICECSSES 836
Score = 79.8 bits (188), Expect = 3e-14
Identities = 62/207 (29%), Positives = 83/207 (40%), Gaps = 24/207 (11%)
Query: 251 GECCPT---CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G C PT C +C L GE EC + C G +C C C
Sbjct: 463 GRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPCAGG--ECINNQGSYTCQ---CRA 517
Query: 308 PQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVD 365
Q ++ C+ +D C N C+N + + C CN GF DG C+D+D
Sbjct: 518 GYQSTLTRTECR---DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMD 574
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADA 424
EC + C N C+N G + C C G+ D C +++ECE T G +
Sbjct: 575 ECSIR-----NMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE--TPGICMNG 626
Query: 425 VCTNTPGSYTCRCRDGYEG--DGYTCM 449
C NT GSY C C G DG C+
Sbjct: 627 RCVNTDGSYRCECFPGLAVGLDGRVCV 653
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/146 (34%), Positives = 69/146 (47%), Gaps = 20/146 (13%)
Query: 304 PCDP-PQQFSVPGEC-CKFCPG-------VDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
PC P P Q S + C PG ++ C + N C NL Y C CN G+
Sbjct: 695 PCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGY 754
Query: 355 QGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK-DKFNCVEVD 411
+ D G C D++EC L+ C N +C N G +VC C G+ K D C ++D
Sbjct: 755 EVDSTGKNCVDINECV----LNSLLC-DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID 809
Query: 412 ECEGNTHGCHADAVCTNTPGSYTCRC 437
ECE + C + VC N+PGS+ C C
Sbjct: 810 ECESSP--C-INGVCKNSPGSFICEC 832
Score = 70.1 bits (164), Expect = 2e-11
Identities = 74/259 (28%), Positives = 94/259 (36%), Gaps = 32/259 (12%)
Query: 221 CNRCSCVHGEITC-RPVECDRAECKNPVLHPGECC--PTCLRQCLLWGNLYEHGERFAPK 277
C S H I C C C + G C P C CL G AP
Sbjct: 111 CGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCL------NGGRCVAPN 164
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK--FCPGVDYCNMGHSCDE 335
CA C QC R C + + Q + G C C GH C+
Sbjct: 165 RCA-CTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCE- 222
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
+ C +GF + T CQDVDECQ GL C C+N VG + C
Sbjct: 223 ------MCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGL----CQGGN-CINTVGSFEC 271
Query: 394 QCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMH 450
+C G+ + C ++DEC C CTNT SY C+C G+ DG C
Sbjct: 272 KCPAGHKLNEVSQKCEDIDECSTIPGICEGGE-CTNTVSSYFCKCPPGFYTSPDGTRC-- 328
Query: 451 VDECTEGSHTCHHSARCVN 469
+D +T + RC N
Sbjct: 329 IDVRPGYCYTALTNGRCSN 347
Score = 66.9 bits (156), Expect = 2e-10
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 33/185 (17%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
K C ++ C + +N C N + C C +GF + D TC+D+DEC+ + ++G
Sbjct: 761 KNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGV 820
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKD-KFNCVE----------VD-ECEGNTHGCHADA 424
C N G ++C+C T K C+E +D CE N +G +
Sbjct: 821 -------CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKS 873
Query: 425 VCTNTPGSY------TCR----CRDGYEG-DGYTCMHVDECTEGSHTCHHSARCVNIDGG 473
C ++ G+ C+ C GY G C +DEC C + CVN G
Sbjct: 874 QCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGL-CVNTRGS 932
Query: 474 FRCEC 478
F+C+C
Sbjct: 933 FKCQC 937
Score = 50.0 bits (114), Expect = 3e-05
Identities = 58/225 (25%), Positives = 81/225 (36%), Gaps = 28/225 (12%)
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP-GECCKFCPG--VDYC 327
G R+ C G QC +C C P + P G+ C + +C
Sbjct: 60 GSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 119
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
N+ C +C + + C C +G+ G Q V C E+G L+G C + RC
Sbjct: 120 NI--RCMNGGSCSDDH----CLCQKGYIGTHCG-QPV--C-ESGCLNGGRCVAPNRCACT 169
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG-CHADAVCTNTPG---SYTCR------- 436
G QC Y F + C+G G +C T G + C
Sbjct: 170 YGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPH 229
Query: 437 -CRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
CR G+ + T C VDEC C C+N G F C+C
Sbjct: 230 PCRRGFIPNIRTGACQDVDECQAIPGLC-QGGNCINTVGSFECKC 273
Score = 41.9 bits (94), Expect = 0.007
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHV 451
C GY+R C ++DECE C + +C NT GS+ C+C G + G C+ +
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGVCK-NGLCVNTRGSFKCQCPSGMTLDATGRICLDI 953
Score = 39.5 bits (88), Expect = 0.037
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 350 CNQGFQG-DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
C +G+ G C+D+DEC+ G+ C N CVN G + CQC G T
Sbjct: 896 CGKGYSRIKGTQCEDIDECEVFPGV----C-KNGLCVNTRGSFKCQCPSGMT 942
>AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding protein
1 (MBP1) protein.
Length = 443
Score = 115 bits (277), Expect = 5e-25
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C + C NL Y C C G++ G C D+DEC+ +C
Sbjct: 121 CVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRY------RYCQ 174
Query: 380 SNTRCVNVVGGYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN+ G + CQC G+ + +CV+V+EC+ G + C N+ G++ CRC
Sbjct: 175 H--RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECD---MGAPCEQRCFNSYGTFLCRCH 229
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE DG++C +DEC+ S+ C + RCVN G F C C
Sbjct: 230 QGYELHRDGFSCSDIDECSYSSYLCQY--RCVNEPGRFSCHC 269
Score = 113 bits (273), Expect = 1e-24
Identities = 88/284 (30%), Positives = 121/284 (42%), Gaps = 35/284 (12%)
Query: 213 DGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
DG W D C V+ +T P C + E K + G C R + +L+ G
Sbjct: 41 DGYEWDPDSQHCRDVNECLTI-PEAC-KGEMKCINHYGGYLCLP--RSAAVINDLHGEGP 96
Query: 273 ------RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVPGECCKFCPGVD 325
P C D C VD E A C P Q ++PG CP
Sbjct: 97 PPPVPPAQHPNPCPPGYEPDDQDSCVDVD-ECAQALHDCRPSQDCHNLPGSYQCTCPD-G 154
Query: 326 YCNMGHSC---DE------NATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
Y +G C DE C+NL + C+C GFQ + +C DV+EC
Sbjct: 155 YRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM----- 209
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C RC N G ++C+C GY +D F+C ++DEC +++ C C N PG +
Sbjct: 210 GAPCEQ--RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRF 265
Query: 434 TCRCRDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
+C C GY+ C +DEC G+H C + CVN GG+RC
Sbjct: 266 SCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 88.2 bits (209), Expect = 8e-17
Identities = 50/146 (34%), Positives = 68/146 (46%), Gaps = 17/146 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGL 359
R C+P Q G + C V+ C+MG C++ C N + C+C+QG++ DG
Sbjct: 185 RCQCEPGFQL---GPNNRSCVDVNECDMGAPCEQR--CFNSYGTFLCRCHQGYELHRDGF 239
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG 419
+C D+DEC + L C RCVN G + C C GY C ++DECE H
Sbjct: 240 SCSDIDECSYSSYL----CQY--RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQ 293
Query: 420 CHADAVCTNTPGSYTC----RCRDGY 441
C C N G Y C RC + Y
Sbjct: 294 CSEAQTCVNFHGGYRCVDTNRCVEPY 319
Score = 87.8 bits (208), Expect = 1e-16
Identities = 39/84 (46%), Positives = 46/84 (54%), Gaps = 4/84 (4%)
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
C GY D+ +CV+VDEC H C C N PGSY C C DGY G C+ +DEC
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDEC 168
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
C H RCVN+ G FRC+C
Sbjct: 169 R--YRYCQH--RCVNLPGSFRCQC 188
>AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein.
Length = 915
Score = 114 bits (275), Expect = 8e-25
Identities = 81/254 (31%), Positives = 111/254 (43%), Gaps = 36/254 (14%)
Query: 248 LHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG------NMQCTRVD----PE 297
L+P E T + C L EH E +E C CH G C+RVD +
Sbjct: 352 LNPDEKTCTRINYCALNKPGCEH-ECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQD 410
Query: 298 LACPRLPCDPPQQFSVP-------GECCKFCPGVDYCNMG-HSCDENATCMNLNTKYTCK 349
C +L + F E K C VDYC + H C+ + C+N++ + C+
Sbjct: 411 HGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFACQ 468
Query: 350 CNQG--FQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFN 406
C +G + DG TC +D C L H C + CV+ +VCQC GY R+D
Sbjct: 469 CPEGHVLRSDGKTCAKLDSC----ALGDHGCEHS--CVSSEDSFVCQCFEGYILREDGKT 522
Query: 407 CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHS 464
C D C+ HGC + +C N+ SYTC C +G+ DG C D C H C H
Sbjct: 523 CRRKDVCQAIDHGC--EHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHI 580
Query: 465 ARCVNIDGGFRCEC 478
CVN + C+C
Sbjct: 581 --CVNNGNSYICKC 592
Score = 114 bits (274), Expect = 1e-24
Identities = 72/226 (31%), Positives = 102/226 (45%), Gaps = 24/226 (10%)
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSV-PGECC 318
QC L E G+R + H +C D C C + F++ P E
Sbjct: 304 QCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQ---CH--EGFALNPDE-- 356
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C ++YC + E+ C+N+ Y C+C++G+ D G TC VD C + H
Sbjct: 357 KTCTRINYCALNKPGCEHE-CVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQ----QDH 411
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C C+N +VCQC G+ +D C VD C + HGC C N S+ C
Sbjct: 412 GCEQ--LCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYS--CVNMDRSFAC 467
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+C +G+ DG TC +D C G H C HS CV+ + F C+CF
Sbjct: 468 QCPEGHVLRSDGKTCAKLDSCALGDHGCEHS--CVSSEDSFVCQCF 511
Score = 109 bits (263), Expect = 2e-23
Identities = 57/165 (34%), Positives = 77/165 (46%), Gaps = 17/165 (10%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
K C + H+C C+N+ Y C+C QG+ D TC+ D C + H
Sbjct: 235 KLCTAHMCSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLC----AMEDH 288
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
+C CVNV G +VCQC GY +D CV VD C HGC + C N GSY C
Sbjct: 289 NCEQ--LCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHE--CVNADGSYLC 344
Query: 436 RCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +G+ D TC ++ C C H CVN++ + C C
Sbjct: 345 QCHEGFALNPDEKTCTRINYCALNKPGCEH--ECVNMEESYYCRC 387
Score = 86.2 bits (204), Expect = 3e-16
Identities = 56/179 (31%), Positives = 79/179 (44%), Gaps = 25/179 (13%)
Query: 285 HDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLN 343
H C +D AC C G K C +D C +G H C+ + C++
Sbjct: 452 HGCEYSCVNMDRSFACQ---CPEGHVLRSDG---KTCAKLDSCALGDHGCEHS--CVSSE 503
Query: 344 TKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT- 400
+ C+C +G+ + DG TC+ D CQ H C CVN Y C+CL G+
Sbjct: 504 DSFVCQCFEGYILREDGKTCRRKDVCQAID----HGCEHI--CVNSDDSYTCECLEGFRL 557
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
+D C D C+ HGC + +C N SY C+C +G+ DG C +CTEG
Sbjct: 558 AEDGKRCRRKDVCKSTHHGC--EHICVNNGNSYICKCSEGFVLAEDGRRC---KKCTEG 611
Score = 59.7 bits (138), Expect = 3e-08
Identities = 28/70 (40%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 413 CEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNI 470
C H C C N PGSY CRC+ GY D TC D C H C CVN+
Sbjct: 242 CSTLEHNCAH--FCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQ--LCVNV 297
Query: 471 DGGFRCECFT 480
G F C+C++
Sbjct: 298 PGSFVCQCYS 307
Score = 38.3 bits (85), Expect = 0.084
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 9/109 (8%)
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
QC L E G+ K+ + + H C D C L + F + E K
Sbjct: 509 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECL-----EGFRL-AEDGK 562
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDE 366
C D C H E+ C+N Y CKC++GF DG C+ E
Sbjct: 563 RCRRKDVCKSTHHGCEHI-CVNNGNSYICKCSEGFVLAEDGRRCKKCTE 610
>AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens
cDNA FLJ16233 fis, clone FEBRA2028256, moderately
similar to FIBRILLIN 2 PRECURSOR. ).
Length = 872
Score = 114 bits (275), Expect = 8e-25
Identities = 75/209 (35%), Positives = 96/209 (45%), Gaps = 24/209 (11%)
Query: 278 ECAEC--VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
ECAE VC +G C D C C P +S+ C D C++GH C +
Sbjct: 193 ECAENPGVCTNG--VCVNTDGSFRCE---C--PFGYSLDFTGIN-CVDTDECSVGHPCGQ 244
Query: 336 NATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
TC N+ + C C GF+ G +TC+D+DEC L CH N G Y+C
Sbjct: 245 G-TCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCH------NTEGSYLCT 297
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAV-CTNTPGSYTCRCRDGYE---GDGYTCM 449
C GYT R+D C +VDEC CHA + C N G++ C C G G G C
Sbjct: 298 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 357
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+EC C + RCVN G FRC+C
Sbjct: 358 DDNECHAQPDLCVNG-RCVNTAGSFRCDC 385
Score = 111 bits (266), Expect = 1e-23
Identities = 59/160 (36%), Positives = 73/160 (45%), Gaps = 13/160 (8%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSN 381
V+ C N C+N + + C+C G+ D G+ C D DEC GH C
Sbjct: 191 VNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-----GHPCGQG 245
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C NV+GG+ C C G+ C ++DEC N C C NT GSY C C GY
Sbjct: 246 T-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGY 302
Query: 442 --EGDGYTCMHVDECTEGSHTCH-HSARCVNIDGGFRCEC 478
DG C VDEC +G CH C N+ G F C C
Sbjct: 303 TLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVC 342
Score = 105 bits (252), Expect = 5e-22
Identities = 69/205 (33%), Positives = 89/205 (43%), Gaps = 22/205 (10%)
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG--VDYCNM-GHSCDEN 336
AEC C G R + CP LP + P G VD C M H C +
Sbjct: 428 AECCCGGGRGWGPRCE---LCP-LPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLC-AH 482
Query: 337 ATCMNLNTKYTCKCNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C+N + C C G+ D TC D+DEC + C C N G ++C
Sbjct: 483 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVP----KPC--TFLCKNTKGSFLCS 536
Query: 395 CLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C GY +D C ++DEC H C +C NT G++TCRC G+ C V+E
Sbjct: 537 CPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQHHQACFDVNE 594
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC 478
C +G H C H C N GG+RC C
Sbjct: 595 C-DGPHRCQHG--CQNQLGGYRCSC 616
Score = 96.3 bits (229), Expect = 3e-19
Identities = 59/178 (33%), Positives = 82/178 (46%), Gaps = 17/178 (9%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD 363
C P+ + + E + C +D C + H+C C+N +TC+C GF C D
Sbjct: 535 CSCPRGYLLE-EDGRTCKDLDECTSRQHNCQ--FLCVNTVGAFTCRCPPGFTQHHQACFD 591
Query: 364 VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHA 422
V+EC H C C N +GGY C C G+T+ ++ CV+ +EC + C
Sbjct: 592 VNECDGP-----HRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTC-G 643
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
A C NT G + C C G++ D C VDEC C +S C N GGF C C
Sbjct: 644 SASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGC 699
Score = 95.9 bits (228), Expect = 4e-19
Identities = 53/144 (36%), Positives = 71/144 (49%), Gaps = 15/144 (10%)
Query: 339 CMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C N + C C +G+ + DG TC+D+DEC H+C CVN VG + C+C
Sbjct: 526 CKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTS----RQHNCQF--LCVNTVGAFTCRCP 579
Query: 397 GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDEC 454
G+T+ + C +V+EC+G H C C N G Y C C G+ C+ +EC
Sbjct: 580 PGFTQHHQA-CFDVNECDG-PHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 635
Query: 455 TEGSHTCHHSARCVNIDGGFRCEC 478
TC SA C N GGFRC C
Sbjct: 636 ALSPPTCG-SASCRNTLGGFRCVC 658
Score = 73.3 bits (172), Expect = 2e-12
Identities = 58/178 (32%), Positives = 71/178 (39%), Gaps = 15/178 (8%)
Query: 265 GNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV 324
G L E R K+ EC N Q V+ A C P F+ + C V
Sbjct: 540 GYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGA---FTCRCPPGFTQHHQACF---DV 592
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
+ C+ H C C N Y C C QGF Q VDE + A L C S + C
Sbjct: 593 NECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGSAS-C 647
Query: 385 VNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
N +GG+ C C G+ C +VDEC G C C NTPG + C C GY
Sbjct: 648 RNTLGGFRCVCPSGFDFDQALGGCQDVDECAGRRGPCSYS--CANTPGGFLCGCPQGY 703
Score = 65.7 bits (153), Expect = 5e-10
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C++ C N Y C C G+ + DG C+DVDEC + C
Sbjct: 270 CEDIDECSLNPLLCA-FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQ----QDC 324
Query: 379 HSN-TRCVNVVGGYVCQCLGGYTRKDKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC 435
H+ C N++G + C C G C + +EC C + C NT GS+ C
Sbjct: 325 HARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLC-VNGRCVNTAGSFRC 383
Query: 436 RCRDGYE 442
C +G++
Sbjct: 384 DCDEGFQ 390
Score = 55.6 bits (128), Expect = 5e-07
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT--CQ 362
C PQ F+ + + C + C + +A+C N + C C GF D CQ
Sbjct: 614 CSCPQGFTQHSQWAQ-CVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 672
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
DVDEC G G +S C N GG++C C GY R + +CV
Sbjct: 673 DVDEC---AGRRGPCSYS---CANTPGGFLCGCPQGYFRAGQGHCV 712
>AC010895-1|AAY14669.1| 320|Homo sapiens unknown protein.
Length = 320
Score = 114 bits (275), Expect = 8e-25
Identities = 57/159 (35%), Positives = 81/159 (50%), Gaps = 16/159 (10%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
+D C G H+C + C+NL + C+C G+Q G C D+DEC +CH
Sbjct: 1 IDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIP-----PYCHQ-- 53
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
RCVN G + CQC G+ + + CV+++EC+ + C C N GS+ C+C GY
Sbjct: 54 RCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQ-CAQQ--CYNILGSFICQCNQGY 110
Query: 442 E--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
E D C +DEC S+ C + +CVN G F C C
Sbjct: 111 ELSSDRLNCEDIDECRTSSYLCQY--QCVNEPGKFSCMC 147
Score = 111 bits (267), Expect = 7e-24
Identities = 62/200 (31%), Positives = 95/200 (47%), Gaps = 20/200 (10%)
Query: 281 ECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCM 340
EC N + +V L C P + GE C +D C + C + C+
Sbjct: 3 ECTAGTHNCRADQVCINLR-GSFACQCPPGYQKRGEQCV---DIDECTIPPYCHQR--CV 56
Query: 341 NLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
N + C+C+ GFQ + TC D++EC + + C +C N++G ++CQC G
Sbjct: 57 NTPGSFYCQCSPGFQLAANNYTCVDINECDAS-----NQCAQ--QCYNILGSFICQCNQG 109
Query: 399 YT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTE 456
Y D+ NC ++DEC +++ C C N PG ++C C GY+ TC ++EC E
Sbjct: 110 YELSSDRLNCEDIDECRTSSYLCQYQ--CVNEPGKFSCMCPQGYQVVRSRTCQDINEC-E 166
Query: 457 GSHTCHHSARCVNIDGGFRC 476
++ C C N GGFRC
Sbjct: 167 TTNECREDEMCWNYHGGFRC 186
Score = 78.6 bits (185), Expect = 6e-14
Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 15/127 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C ++ C+ + C + C N+ + C+CNQG++ D L C+D+DEC+ + L C
Sbjct: 79 CVDINECDASNQCAQQ--CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYL----C 132
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTC--- 435
+CVN G + C C GY C +++ECE T+ C D +C N G + C
Sbjct: 133 QY--QCVNEPGKFSCMCPQGYQVVRSRTCQDINECE-TTNECREDEMCWNYHGGFRCYPR 189
Query: 436 -RCRDGY 441
C+D Y
Sbjct: 190 NPCQDPY 196
>DQ217942-1|ABB70739.1| 886|Homo sapiens EGF-like module containing
mucin-like hormone receptor-like 1 protein.
Length = 886
Score = 114 bits (274), Expect = 1e-24
Identities = 69/222 (31%), Positives = 94/222 (42%), Gaps = 29/222 (13%)
Query: 278 ECAECVCHDG-NMQCTRVDPELACPRLP--CDPPQQFSVPGECCKF-CPGVDYCNMGHSC 333
EC++ G N C + C L P VPG+ F C ++ C C
Sbjct: 83 ECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVC 142
Query: 334 DENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
E++ C+N Y+C C GF TC+DVDEC + C + C N VG Y C
Sbjct: 143 PEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADP-----RACPEHATCNNTVGNYSC 197
Query: 394 QCLGGYTRKD--------KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG----- 440
C G+ K +C ++DEC T C ++ CTNTPGSY C C G
Sbjct: 198 FCNPGFESSSGHLSFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSN 254
Query: 441 ----YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G C +DEC + TC ++ C N G + C C
Sbjct: 255 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
Score = 98.3 bits (234), Expect = 7e-20
Identities = 54/171 (31%), Positives = 77/171 (45%), Gaps = 25/171 (14%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQG---------FQGDGLTCQDVDECQEAGGLHGHH 377
C C ATC N Y C C QG F+ G+ C+D+DEC ++
Sbjct: 35 CRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQS----PQP 90
Query: 378 CHSNTRCVNVVGGYVCQCLGGYT----------RKDKFNCVEVDECEGNTHGCHADAVCT 427
C N+ C N+ G Y C CL G++ + F+C +++EC + C + C
Sbjct: 91 CGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECL-TSSVCPEHSDCV 149
Query: 428 NTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
N+ GSY+C C+ G+ TC VDEC + C A C N G + C C
Sbjct: 150 NSMGSYSCSCQVGFISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFC 199
Score = 87.4 bits (207), Expect = 1e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 24/138 (17%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF---------QGDGLTCQDVDECQEAG 371
C VD C +C E+ATC N Y+C CN GF QG +C+D+DEC E
Sbjct: 170 CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM- 228
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFN-------CVEVDECEGNTHGCHAD 423
C N+ C N G Y C C G+ + + N C ++DEC + C +
Sbjct: 229 ------CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPN 282
Query: 424 AVCTNTPGSYTCRCRDGY 441
++CTN GSY+C C G+
Sbjct: 283 SICTNALGSYSCGCIAGF 300
Score = 56.0 bits (129), Expect = 4e-07
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
Query: 398 GYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---------EGDGYTC 448
G+ R + + + C +T C A A CTNT SY C C+ G+ + G C
Sbjct: 20 GHIRPTRKPNTKGNNCRDSTL-CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC 78
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+DEC++ C ++ C N+ G ++C C
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSC 108
>CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 114 bits (274), Expect = 1e-24
Identities = 58/161 (36%), Positives = 83/161 (51%), Gaps = 17/161 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C G+ C + C N+ Y+C CN GF DG +CQDV+EC + C
Sbjct: 166 CLDIDECRYGY-CQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-----NPC 217
Query: 379 HSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G ++C+C GY +D +C ++DEC + C + C N PG+Y C C
Sbjct: 218 VQT--CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE--CVNQPGTYFCSC 273
Query: 438 RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY D +C ++EC +HTC+ C N+ GGF+C
Sbjct: 274 PPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 103 bits (247), Expect = 2e-21
Identities = 60/162 (37%), Positives = 77/162 (47%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNM-GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C+ C+N YTC C G+ C D+DEC+ +G +C
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECR-----YG-YCQ 178
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
C NV G Y C C G+T +D +C +V+EC + C C NT GS+ CRC
Sbjct: 179 Q--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPC--VQTCVNTYGSFICRCD 233
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY E DG C +DEC+ C H CVN G + C C
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSC 273
Score = 91.5 bits (217), Expect = 9e-18
Identities = 49/132 (37%), Positives = 65/132 (49%), Gaps = 15/132 (11%)
Query: 350 CNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C G+Q D C DVDEC H C+ C+N GGY C C GY + C+
Sbjct: 113 CRFGYQMDESNQCVDVDEC----ATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG-QCL 167
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC +G + +C N PGSY+C C G+ DG +C V+EC + C +
Sbjct: 168 DIDECR---YG-YCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQT-- 220
Query: 467 CVNIDGGFRCEC 478
CVN G F C C
Sbjct: 221 CVNTYGSFICRC 232
Score = 65.3 bits (152), Expect = 6e-10
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 8/146 (5%)
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
A C+ +C GF D + C D+DEC+ C + CVN GGY+C
Sbjct: 14 ALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIP----EACRGDMMCVNQNGGYLCI 69
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGD-GYTCMHVD 452
+ ++ G N P S CR GY+ D C+ VD
Sbjct: 70 PRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVD 129
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC SH C+ + C+N +GG+ C C
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSC 155
>BC059395-1|AAH59395.1| 821|Homo sapiens EMR1 protein protein.
Length = 821
Score = 114 bits (274), Expect = 1e-24
Identities = 69/222 (31%), Positives = 94/222 (42%), Gaps = 29/222 (13%)
Query: 278 ECAECVCHDG-NMQCTRVDPELACPRLP--CDPPQQFSVPGECCKF-CPGVDYCNMGHSC 333
EC++ G N C + C L P VPG+ F C ++ C C
Sbjct: 83 ECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVC 142
Query: 334 DENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
E++ C+N Y+C C GF TC+DVDEC + C + C N VG Y C
Sbjct: 143 PEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADP-----RACPEHATCNNTVGNYSC 197
Query: 394 QCLGGYTRKD--------KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG----- 440
C G+ K +C ++DEC T C ++ CTNTPGSY C C G
Sbjct: 198 FCNPGFESSSGHLSFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSN 254
Query: 441 ----YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G C +DEC + TC ++ C N G + C C
Sbjct: 255 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
Score = 98.3 bits (234), Expect = 7e-20
Identities = 54/171 (31%), Positives = 77/171 (45%), Gaps = 25/171 (14%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQG---------FQGDGLTCQDVDECQEAGGLHGHH 377
C C ATC N Y C C QG F+ G+ C+D+DEC ++
Sbjct: 35 CRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQS----PQP 90
Query: 378 CHSNTRCVNVVGGYVCQCLGGYT----------RKDKFNCVEVDECEGNTHGCHADAVCT 427
C N+ C N+ G Y C CL G++ + F+C +++EC + C + C
Sbjct: 91 CGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECL-TSSVCPEHSDCV 149
Query: 428 NTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
N+ GSY+C C+ G+ TC VDEC + C A C N G + C C
Sbjct: 150 NSMGSYSCSCQVGFISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFC 199
Score = 87.4 bits (207), Expect = 1e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 24/138 (17%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF---------QGDGLTCQDVDECQEAG 371
C VD C +C E+ATC N Y+C CN GF QG +C+D+DEC E
Sbjct: 170 CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM- 228
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFN-------CVEVDECEGNTHGCHAD 423
C N+ C N G Y C C G+ + + N C ++DEC + C +
Sbjct: 229 ------CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPN 282
Query: 424 AVCTNTPGSYTCRCRDGY 441
++CTN GSY+C C G+
Sbjct: 283 SICTNALGSYSCGCIAGF 300
Score = 56.0 bits (129), Expect = 4e-07
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
Query: 398 GYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---------EGDGYTC 448
G+ R + + + C +T C A A CTNT SY C C+ G+ + G C
Sbjct: 20 GHIRPTRKPNTKGNNCRDSTL-CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC 78
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+DEC++ C ++ C N+ G ++C C
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSC 108
>BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein.
Length = 448
Score = 114 bits (274), Expect = 1e-24
Identities = 58/161 (36%), Positives = 83/161 (51%), Gaps = 17/161 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C G+ C + C N+ Y+C CN GF DG +CQDV+EC + C
Sbjct: 166 CLDIDECRYGY-CQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-----NPC 217
Query: 379 HSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G ++C+C GY +D +C ++DEC + C + C N PG+Y C C
Sbjct: 218 VQT--CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE--CVNQPGTYFCSC 273
Query: 438 RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY D +C ++EC +HTC+ C N+ GGF+C
Sbjct: 274 PPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 103 bits (247), Expect = 2e-21
Identities = 60/162 (37%), Positives = 77/162 (47%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNM-GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C+ C+N YTC C G+ C D+DEC+ +G +C
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECR-----YG-YCQ 178
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
C NV G Y C C G+T +D +C +V+EC + C C NT GS+ CRC
Sbjct: 179 Q--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPC--VQTCVNTYGSFICRCD 233
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY E DG C +DEC+ C H CVN G + C C
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSC 273
Score = 91.5 bits (217), Expect = 9e-18
Identities = 49/132 (37%), Positives = 65/132 (49%), Gaps = 15/132 (11%)
Query: 350 CNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C G+Q D C DVDEC H C+ C+N GGY C C GY + C+
Sbjct: 113 CRFGYQMDESNQCVDVDEC----ATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG-QCL 167
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC +G + +C N PGSY+C C G+ DG +C V+EC + C +
Sbjct: 168 DIDECR---YG-YCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQT-- 220
Query: 467 CVNIDGGFRCEC 478
CVN G F C C
Sbjct: 221 CVNTYGSFICRC 232
Score = 65.3 bits (152), Expect = 6e-10
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 8/146 (5%)
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
A C+ +C GF D + C D+DEC+ C + CVN GGY+C
Sbjct: 14 ALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIP----EACRGDMMCVNQNGGYLCI 69
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGD-GYTCMHVD 452
+ ++ G N P S CR GY+ D C+ VD
Sbjct: 70 PRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVD 129
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC SH C+ + C+N +GG+ C C
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSC 155
>AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein.
Length = 448
Score = 114 bits (274), Expect = 1e-24
Identities = 58/161 (36%), Positives = 83/161 (51%), Gaps = 17/161 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C G+ C + C N+ Y+C CN GF DG +CQDV+EC + C
Sbjct: 166 CLDIDECRYGY-CQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-----NPC 217
Query: 379 HSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G ++C+C GY +D +C ++DEC + C + C N PG+Y C C
Sbjct: 218 VQT--CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE--CVNQPGTYFCSC 273
Query: 438 RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY D +C ++EC +HTC+ C N+ GGF+C
Sbjct: 274 PPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 103 bits (247), Expect = 2e-21
Identities = 60/162 (37%), Positives = 77/162 (47%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNM-GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C+ C+N YTC C G+ C D+DEC+ +G +C
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECR-----YG-YCQ 178
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
C NV G Y C C G+T +D +C +V+EC + C C NT GS+ CRC
Sbjct: 179 Q--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPC--VQTCVNTYGSFICRCD 233
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY E DG C +DEC+ C H CVN G + C C
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSC 273
Score = 91.5 bits (217), Expect = 9e-18
Identities = 49/132 (37%), Positives = 65/132 (49%), Gaps = 15/132 (11%)
Query: 350 CNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C G+Q D C DVDEC H C+ C+N GGY C C GY + C+
Sbjct: 113 CRFGYQMDESNQCVDVDEC----ATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG-QCL 167
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC +G + +C N PGSY+C C G+ DG +C V+EC + C +
Sbjct: 168 DIDECR---YG-YCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQT-- 220
Query: 467 CVNIDGGFRCEC 478
CVN G F C C
Sbjct: 221 CVNTYGSFICRC 232
Score = 65.3 bits (152), Expect = 6e-10
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 8/146 (5%)
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
A C+ +C GF D + C D+DEC+ C + CVN GGY+C
Sbjct: 14 ALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIP----EACRGDMMCVNQNGGYLCI 69
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGD-GYTCMHVD 452
+ ++ G N P S CR GY+ D C+ VD
Sbjct: 70 PRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVD 129
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC SH C+ + C+N +GG+ C C
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSC 155
>AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries and
neural crest EGF-like protein protein.
Length = 448
Score = 114 bits (274), Expect = 1e-24
Identities = 58/161 (36%), Positives = 83/161 (51%), Gaps = 17/161 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C G+ C + C N+ Y+C CN GF DG +CQDV+EC + C
Sbjct: 166 CLDIDECRYGY-CQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-----NPC 217
Query: 379 HSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G ++C+C GY +D +C ++DEC + C + C N PG+Y C C
Sbjct: 218 VQT--CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE--CVNQPGTYFCSC 273
Query: 438 RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY D +C ++EC +HTC+ C N+ GGF+C
Sbjct: 274 PPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 103 bits (247), Expect = 2e-21
Identities = 60/162 (37%), Positives = 77/162 (47%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNM-GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C+ C+N YTC C G+ C D+DEC+ +G +C
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECR-----YG-YCQ 178
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
C NV G Y C C G+T +D +C +V+EC + C C NT GS+ CRC
Sbjct: 179 Q--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPC--VQTCVNTYGSFICRCD 233
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY E DG C +DEC+ C H CVN G + C C
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSC 273
Score = 91.5 bits (217), Expect = 9e-18
Identities = 49/132 (37%), Positives = 65/132 (49%), Gaps = 15/132 (11%)
Query: 350 CNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C G+Q D C DVDEC H C+ C+N GGY C C GY + C+
Sbjct: 113 CRFGYQMDESNQCVDVDEC----ATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG-QCL 167
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC +G + +C N PGSY+C C G+ DG +C V+EC + C +
Sbjct: 168 DIDECR---YG-YCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQT-- 220
Query: 467 CVNIDGGFRCEC 478
CVN G F C C
Sbjct: 221 CVNTYGSFICRC 232
Score = 65.3 bits (152), Expect = 6e-10
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 8/146 (5%)
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
A C+ +C GF D + C D+DEC+ C + CVN GGY+C
Sbjct: 14 ALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIP----EACRGDMMCVNQNGGYLCI 69
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGD-GYTCMHVD 452
+ ++ G N P S CR GY+ D C+ VD
Sbjct: 70 PRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVD 129
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC SH C+ + C+N +GG+ C C
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSC 155
>AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein.
Length = 448
Score = 114 bits (274), Expect = 1e-24
Identities = 58/161 (36%), Positives = 83/161 (51%), Gaps = 17/161 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C G+ C + C N+ Y+C CN GF DG +CQDV+EC + C
Sbjct: 166 CLDIDECRYGY-CQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-----NPC 217
Query: 379 HSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G ++C+C GY +D +C ++DEC + C + C N PG+Y C C
Sbjct: 218 VQT--CVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE--CVNQPGTYFCSC 273
Query: 438 RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY D +C ++EC +HTC+ C N+ GGF+C
Sbjct: 274 PPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 104 bits (250), Expect = 9e-22
Identities = 60/162 (37%), Positives = 78/162 (48%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNM-GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C+ C+N+ YTC C G+ C D+DEC+ +G +C
Sbjct: 125 CVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYWLLEGQCLDIDECR-----YG-YCQ 178
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
C NV G Y C C G+T +D +C +V+EC + C C NT GS+ CRC
Sbjct: 179 Q--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPC--VQTCVNTYGSFICRCD 233
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY E DG C +DEC+ C H CVN G + C C
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSC 273
Score = 91.9 bits (218), Expect = 6e-18
Identities = 49/132 (37%), Positives = 66/132 (50%), Gaps = 15/132 (11%)
Query: 350 CNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C G+Q D C DVDEC H C+ C+N+ GGY C C GY + C+
Sbjct: 113 CRFGYQMDESNQCVDVDEC----ATDSHQCNPTQICINMKGGYTCSCTDGYWLLEG-QCL 167
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC +G + +C N PGSY+C C G+ DG +C V+EC + C +
Sbjct: 168 DIDECR---YG-YCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQT-- 220
Query: 467 CVNIDGGFRCEC 478
CVN G F C C
Sbjct: 221 CVNTYGSFICRC 232
Score = 66.9 bits (156), Expect = 2e-10
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 8/146 (5%)
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
A C+ +C GF D + C D+DEC+ C + CVN GGY+C
Sbjct: 14 ALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIP----EACRGDMMCVNQNGGYLCH 69
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGD-GYTCMHVD 452
+ ++ G N P S CR GY+ D C+ VD
Sbjct: 70 SRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVD 129
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC SH C+ + C+N+ GG+ C C
Sbjct: 130 ECATDSHQCNPTQICINMKGGYTCSC 155
Score = 45.2 bits (102), Expect = 7e-04
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
Query: 424 AVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
A+C +PG+ +C +G++ D + C+ +DEC C CVN +GG+ C T
Sbjct: 14 ALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCHSRT 72
>AB065918-1|BAC06133.1| 929|Homo sapiens seven transmembrane helix
receptor protein.
Length = 929
Score = 114 bits (274), Expect = 1e-24
Identities = 69/222 (31%), Positives = 94/222 (42%), Gaps = 29/222 (13%)
Query: 278 ECAECVCHDG-NMQCTRVDPELACPRLP--CDPPQQFSVPGECCKF-CPGVDYCNMGHSC 333
EC++ G N C + C L P VPG+ F C ++ C C
Sbjct: 101 ECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVC 160
Query: 334 DENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
E++ C+N Y+C C GF TC+DVDEC + C + C N VG Y C
Sbjct: 161 PEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADP-----RACPEHATCNNTVGNYSC 215
Query: 394 QCLGGYTRKD--------KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG----- 440
C G+ K +C ++DEC T C ++ CTNTPGSY C C G
Sbjct: 216 FCNPGFESSSGHLSFQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSN 272
Query: 441 ----YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G C +DEC + TC ++ C N G + C C
Sbjct: 273 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 314
Score = 98.3 bits (234), Expect = 7e-20
Identities = 54/171 (31%), Positives = 77/171 (45%), Gaps = 25/171 (14%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQG---------FQGDGLTCQDVDECQEAGGLHGHH 377
C C ATC N Y C C QG F+ G+ C+D+DEC ++
Sbjct: 53 CRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQS----PQP 108
Query: 378 CHSNTRCVNVVGGYVCQCLGGYT----------RKDKFNCVEVDECEGNTHGCHADAVCT 427
C N+ C N+ G Y C CL G++ + F+C +++EC + C + C
Sbjct: 109 CGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECL-TSSVCPEHSDCV 167
Query: 428 NTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
N+ GSY+C C+ G+ TC VDEC + C A C N G + C C
Sbjct: 168 NSMGSYSCSCQVGFISRNSTCEDVDECAD-PRACPEHATCNNTVGNYSCFC 217
Score = 87.4 bits (207), Expect = 1e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 24/138 (17%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF---------QGDGLTCQDVDECQEAG 371
C VD C +C E+ATC N Y+C CN GF QG +C+D+DEC E
Sbjct: 188 CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM- 246
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFN-------CVEVDECEGNTHGCHAD 423
C N+ C N G Y C C G+ + + N C ++DEC + C +
Sbjct: 247 ------CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPN 300
Query: 424 AVCTNTPGSYTCRCRDGY 441
++CTN GSY+C C G+
Sbjct: 301 SICTNALGSYSCGCIAGF 318
Score = 56.0 bits (129), Expect = 4e-07
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
Query: 398 GYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---------EGDGYTC 448
G+ R + + + C +T C A A CTNT SY C C+ G+ + G C
Sbjct: 38 GHIRPTRKPNTKGNNCRDSTL-CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC 96
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+DEC++ C ++ C N+ G ++C C
Sbjct: 97 KDIDECSQSPQPCGPNSSCKNLSGRYKCSC 126
>BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB
domain, EGF-like 3 protein.
Length = 992
Score = 113 bits (273), Expect = 1e-24
Identities = 67/186 (36%), Positives = 87/186 (46%), Gaps = 23/186 (12%)
Query: 319 KFCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
K VD C G +C +A C N Y C C G+ GDG C+DVDEC+ H
Sbjct: 25 KAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVH 84
Query: 378 CHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
CVN+ G Y C C G+ D NC++VDEC GC C N GSY C
Sbjct: 85 -----DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS--CVNMMGSYECH 137
Query: 437 CRDGY--EGDGYTCMHVDE---CTEGSHTCHHSARCVNIDGGFRCEC-----FTEN---C 483
CR+G+ + +TC+ E C +H C H R GG CEC T+N C
Sbjct: 138 CREGFFLSDNQHTCIQRPEGMNCMNKNHGCAHICR-ETPKGGIACECRPGFELTKNQRDC 196
Query: 484 ELSCSW 489
+L+C++
Sbjct: 197 KLTCNY 202
Score = 78.6 bits (185), Expect = 6e-14
Identities = 65/227 (28%), Positives = 92/227 (40%), Gaps = 29/227 (12%)
Query: 277 KECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CD 334
K C E C ++G D + + C P F + + K C +D C + + CD
Sbjct: 233 KTCIETCAVNNGGCDSKCHDAAIG---VHCTCPVGFMLQPDR-KTCKDIDECRLNNGGCD 288
Query: 335 ENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C N + C C +G++ + CQD+DEC C + CVN G +
Sbjct: 289 H--ICRNTVGSFECSCKKGYKLLINERNCQDIDECS-----FDRTC--DHICVNTPGSFQ 339
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG---YEGDGYTCM 449
C C GY +C +VDEC N GC C NTPGSY C C G +G C
Sbjct: 340 CLCHRGYLLYGITHCGDVDECSINRGGCRFG--CINTPGSYQCTCPAGQGRLHWNGKDCT 397
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
+C +GS + N G + C L+C + R + E
Sbjct: 398 EPLKC-QGSPGASKAMLSCNRSGK------KDTCALTCPSRARFLPE 437
>AF525689-1|AAN77133.1| 988|Homo sapiens signal
peptide-CUB-EGF-like domain containing protein 1
protein.
Length = 988
Score = 113 bits (273), Expect = 1e-24
Identities = 59/163 (36%), Positives = 79/163 (48%), Gaps = 15/163 (9%)
Query: 324 VDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNT 382
VD C+ G C +A C N Y C C G++G+G C D+DEC E +G H
Sbjct: 34 VDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQCGDIDEC-ENDYYNGGCVH--- 89
Query: 383 RCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
C+N+ G Y C C G+ D NC++VDEC+ N GC +C N GSY C+C G+
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC--QQICVNAMGSYECQCHSGF 147
Query: 442 --EGDGYTCMHVD----ECTEGSHTCHHSARCVNIDGGFRCEC 478
+ +TC+H C H C H R GG C+C
Sbjct: 148 FLSDNQHTCIHRSNEGMNCMNKDHGCAHICR-ETPKGGVACDC 189
Score = 85.8 bits (203), Expect = 4e-16
Identities = 33/72 (45%), Positives = 42/72 (58%)
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
V+VDEC T CH DA+C N P SY C C+ GY+G+G C +DEC + C
Sbjct: 32 VDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQCGDIDECENDYYNGGCVHEC 91
Query: 468 VNIDGGFRCECF 479
+NI G +RC CF
Sbjct: 92 INIPGNYRCTCF 103
Score = 78.6 bits (185), Expect = 6e-14
Identities = 64/225 (28%), Positives = 95/225 (42%), Gaps = 29/225 (12%)
Query: 272 ERFAP----KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYC 327
+++AP + C E C N C R + A + C P F++ + K C ++ C
Sbjct: 230 QKYAPHSDGRTCIE-TCAVNNGGCDRTCKDTATG-VRCSCPVGFTLQPDG-KTCKDINEC 286
Query: 328 NMGHS-CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
+ + CD C N + C C +G++ D TCQD+DEC C + C
Sbjct: 287 LVNNGGCDH--FCRNTVGSFECGCRKGYKLLTDERTCQDIDECS-----FERTC--DHIC 337
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YE 442
+N G + C C GY +C +VDEC + C D C NT GSY C C G
Sbjct: 338 INSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSC--DQGCVNTKGSYECVCPPGRRLH 395
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+ C+ +C + T + + GG E+C LSC
Sbjct: 396 WNRKDCVETGKCLSRAKTSPRAQLSCSKAGG------VESCFLSC 434
Score = 48.4 bits (110), Expect = 8e-05
Identities = 43/168 (25%), Positives = 62/168 (36%), Gaps = 25/168 (14%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGF--QGDGLTC----QDVDECQEAGGL 373
C VD C + C + C+N Y C+C+ GF + TC + C
Sbjct: 115 CLDVDECQDNNGGCQQ--ICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHG 172
Query: 374 HGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGS 432
H C + GG C C G+ +++ +C C GC C +T
Sbjct: 173 CAHICRETPK-----GGVACDCRPGFDLAQNQKDCTLT--CNYGNGGCQHS--CEDTDTG 223
Query: 433 YTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
TC C Y DG TC ++ C + C + C + G RC C
Sbjct: 224 PTCGCHQKYAPHSDGRTC--IETCAVNNGGCDRT--CKDTATGVRCSC 267
>Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA sequence
from clone RP3-329A5 on chromosome 6p21.1-21.33. ).
Length = 993
Score = 113 bits (271), Expect = 2e-24
Identities = 67/187 (35%), Positives = 87/187 (46%), Gaps = 24/187 (12%)
Query: 319 KFCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
K VD C G +C +A C N Y C C G+ GDG C+DVDEC+ H
Sbjct: 25 KAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVH 84
Query: 378 CHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
CVN+ G Y C C G+ D NC++VDEC GC C N GSY C
Sbjct: 85 -----DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS--CVNMMGSYECH 137
Query: 437 CRDGY--EGDGYTCMHVDE----CTEGSHTCHHSARCVNIDGGFRCEC-----FTEN--- 482
CR+G+ + +TC+ E C +H C H R GG CEC T+N
Sbjct: 138 CREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICR-ETPKGGIACECRPGFELTKNQRD 196
Query: 483 CELSCSW 489
C+L+C++
Sbjct: 197 CKLTCNY 203
Score = 79.0 bits (186), Expect = 5e-14
Identities = 66/227 (29%), Positives = 92/227 (40%), Gaps = 29/227 (12%)
Query: 277 KECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CD 334
K C E C ++G D A + C P F + + K C +D C + + CD
Sbjct: 234 KTCIETCAVNNGGCDSKCHD---AATGVHCTCPVGFMLQPDR-KTCKDIDECRLNNGGCD 289
Query: 335 ENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C N + C C +G++ + CQD+DEC C + CVN G +
Sbjct: 290 H--ICRNTVGSFECSCKKGYKLLINERNCQDIDECS-----FDRTC--DHICVNTPGSFQ 340
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG---YEGDGYTCM 449
C C GY +C +VDEC N GC C NTPGSY C C G +G C
Sbjct: 341 CLCHRGYLLYGITHCGDVDECSINRGGCRFG--CINTPGSYQCTCPAGQGRLHWNGKDCT 398
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
+C +GS + N G + C L+C + R + E
Sbjct: 399 EPLKC-QGSPGASKAMLSCNRSGK------KDTCALTCPSRARFLPE 438
>AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and
EGF-like domain containing protein 3 protein.
Length = 993
Score = 113 bits (271), Expect = 2e-24
Identities = 67/187 (35%), Positives = 87/187 (46%), Gaps = 24/187 (12%)
Query: 319 KFCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
K VD C G +C +A C N Y C C G+ GDG C+DVDEC+ H
Sbjct: 25 KAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVH 84
Query: 378 CHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
CVN+ G Y C C G+ D NC++VDEC GC C N GSY C
Sbjct: 85 -----DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS--CVNMMGSYECH 137
Query: 437 CRDGY--EGDGYTCMHVDE----CTEGSHTCHHSARCVNIDGGFRCEC-----FTEN--- 482
CR+G+ + +TC+ E C +H C H R GG CEC T+N
Sbjct: 138 CREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICR-ETPKGGIACECRPGFELTKNQRD 196
Query: 483 CELSCSW 489
C+L+C++
Sbjct: 197 CKLTCNY 203
Score = 79.0 bits (186), Expect = 5e-14
Identities = 66/227 (29%), Positives = 92/227 (40%), Gaps = 29/227 (12%)
Query: 277 KECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CD 334
K C E C ++G D A + C P F + + K C +D C + + CD
Sbjct: 234 KTCIETCAVNNGGCDSKCHD---AATGVHCTCPVGFMLQPDR-KTCKDIDECRLNNGGCD 289
Query: 335 ENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C N + C C +G++ + CQD+DEC C + CVN G +
Sbjct: 290 H--ICRNTVGSFECSCKKGYKLLINERNCQDIDECS-----FDRTC--DHICVNTPGSFQ 340
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG---YEGDGYTCM 449
C C GY +C +VDEC N GC C NTPGSY C C G +G C
Sbjct: 341 CLCHRGYLLYGITHCGDVDECSINRGGCRFG--CINTPGSYQCTCPAGQGRLHWNGKDCT 398
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
+C +GS + N G + C L+C + R + E
Sbjct: 399 EPLKC-QGSPGASKAMLSCNRSGK------KDTCALTCPSRARFLPE 438
>AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing
protein protein.
Length = 993
Score = 113 bits (271), Expect = 2e-24
Identities = 67/187 (35%), Positives = 87/187 (46%), Gaps = 24/187 (12%)
Query: 319 KFCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
K VD C G +C +A C N Y C C G+ GDG C+DVDEC+ H
Sbjct: 25 KAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVH 84
Query: 378 CHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
CVN+ G Y C C G+ D NC++VDEC GC C N GSY C
Sbjct: 85 -----DCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS--CVNMMGSYECH 137
Query: 437 CRDGY--EGDGYTCMHVDE----CTEGSHTCHHSARCVNIDGGFRCEC-----FTEN--- 482
CR+G+ + +TC+ E C +H C H R GG CEC T+N
Sbjct: 138 CREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICR-ETPKGGIACECRPGFELTKNQRD 196
Query: 483 CELSCSW 489
C+L+C++
Sbjct: 197 CKLTCNY 203
Score = 79.0 bits (186), Expect = 5e-14
Identities = 66/227 (29%), Positives = 92/227 (40%), Gaps = 29/227 (12%)
Query: 277 KECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CD 334
K C E C ++G D A + C P F + + K C +D C + + CD
Sbjct: 234 KTCIETCAVNNGGCDSKCHD---AATGVHCTCPVGFMLQPDR-KTCKDIDECRLNNGGCD 289
Query: 335 ENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C N + C C +G++ + CQD+DEC C + CVN G +
Sbjct: 290 H--ICRNTVGSFECSCKKGYKLLINERNCQDIDECS-----FDRTC--DHICVNTPGSFQ 340
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG---YEGDGYTCM 449
C C GY +C +VDEC N GC C NTPGSY C C G +G C
Sbjct: 341 CLCHRGYLLYGITHCGDVDECSINRGGCRFG--CINTPGSYQCTCPAGQGRLHWNGKDCT 398
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
+C +GS + N G + C L+C + R + E
Sbjct: 399 EPLKC-QGSPGASKAMLSCNRSGK------KDTCALTCPSRARFLPE 438
>X81479-1|CAA57232.1| 886|Homo sapiens EMR1 protein.
Length = 886
Score = 112 bits (270), Expect = 3e-24
Identities = 68/222 (30%), Positives = 94/222 (42%), Gaps = 29/222 (13%)
Query: 278 ECAECVCHDG-NMQCTRVDPELACPRLP--CDPPQQFSVPGECCKF-CPGVDYCNMGHSC 333
EC++ G N C + C L P VPG+ F C ++ C C
Sbjct: 83 ECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSRVC 142
Query: 334 DENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
E++ C+N Y+C C GF TC+DV+EC + C + C N VG Y C
Sbjct: 143 PEHSDCVNSMGSYSCSCQVGFISRNSTCEDVNECADP-----RACPEHATCNNTVGNYSC 197
Query: 394 QCLGGYTRKD--------KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG----- 440
C G+ K +C ++DEC T C ++ CTNTPGSY C C G
Sbjct: 198 FCNPGFESSSGHLSCQGLKASCEDIDEC---TEMCPINSTCTNTPGSYFCTCHPGFAPSS 254
Query: 441 ----YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G C +DEC + TC ++ C N G + C C
Sbjct: 255 GQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGC 296
Score = 96.7 bits (230), Expect = 2e-19
Identities = 53/171 (30%), Positives = 77/171 (45%), Gaps = 25/171 (14%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQG---------FQGDGLTCQDVDECQEAGGLHGHH 377
C C ATC N Y C C QG F+ G+ C+D+DEC ++
Sbjct: 35 CRDSTLCPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRCKDIDECSQS----PQP 90
Query: 378 CHSNTRCVNVVGGYVCQCLGGYT----------RKDKFNCVEVDECEGNTHGCHADAVCT 427
C N+ C N+ G Y C CL G++ + F+C +++EC + C + C
Sbjct: 91 CGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECL-TSRVCPEHSDCV 149
Query: 428 NTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
N+ GSY+C C+ G+ TC V+EC + C A C N G + C C
Sbjct: 150 NSMGSYSCSCQVGFISRNSTCEDVNECAD-PRACPEHATCNNTVGNYSCFC 199
Score = 84.6 bits (200), Expect = 1e-15
Identities = 47/138 (34%), Positives = 65/138 (47%), Gaps = 24/138 (17%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF---------QGDGLTCQDVDECQEAG 371
C V+ C +C E+ATC N Y+C CN GF QG +C+D+DEC E
Sbjct: 170 CEDVNECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSCQGLKASCEDIDECTEM- 228
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFN-------CVEVDECEGNTHGCHAD 423
C N+ C N G Y C C G+ + N C ++DEC + C +
Sbjct: 229 ------CPINSTCTNTPGSYFCTCHPGFAPSSGQLNFTDQGVECRDIDECRQDPSTCGPN 282
Query: 424 AVCTNTPGSYTCRCRDGY 441
++CTN GSY+C C G+
Sbjct: 283 SICTNALGSYSCGCIVGF 300
Score = 56.0 bits (129), Expect = 4e-07
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
Query: 398 GYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---------EGDGYTC 448
G+ R + + + C +T C A A CTNT SY C C+ G+ + G C
Sbjct: 20 GHIRPTRKPNTKGNNCRDSTL-CPAYATCTNTVDSYYCTCKQGFLSSNGQNHFKDPGVRC 78
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+DEC++ C ++ C N+ G ++C C
Sbjct: 79 KDIDECSQSPQPCGPNSSCKNLSGRYKCSC 108
>AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein.
Length = 448
Score = 112 bits (270), Expect = 3e-24
Identities = 58/161 (36%), Positives = 82/161 (50%), Gaps = 17/161 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHC 378
C +D C G+ C + C N+ Y+C CN GF DG +CQDV+EC + C
Sbjct: 166 CLDIDECRYGY-CQQ--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATE-----NPC 217
Query: 379 HSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G +C+C GY +D +C ++DEC + C + C N PG+Y C C
Sbjct: 218 VQT--CVNTYGSLICRCDPGYELEEDGVHCSDMDECSFSEFLCQHE--CVNQPGTYFCSC 273
Query: 438 RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY D +C ++EC +HTC+ C N+ GGF+C
Sbjct: 274 PPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGGFKC 314
Score = 101 bits (243), Expect = 6e-21
Identities = 60/162 (37%), Positives = 76/162 (46%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNM-GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H C+ C+N YTC C G+ C D+DEC+ +G +C
Sbjct: 125 CVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECR-----YG-YCQ 178
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
C NV G Y C C G+T +D +C +V+EC + C C NT GS CRC
Sbjct: 179 Q--LCANVPGSYSCTCNPGFTLNEDGRSCQDVNEC-ATENPC--VQTCVNTYGSLICRCD 233
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY E DG C +DEC+ C H CVN G + C C
Sbjct: 234 PGYELEEDGVHCSDMDECSFSEFLCQH--ECVNQPGTYFCSC 273
Score = 89.0 bits (211), Expect = 5e-17
Identities = 48/132 (36%), Positives = 64/132 (48%), Gaps = 15/132 (11%)
Query: 350 CNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C G+Q D C DVDEC H C+ C+N GGY C C GY + C+
Sbjct: 113 CRFGYQMDESNQCVDVDEC----ATDSHQCNPTQICINTEGGYTCSCTDGYWLLEG-QCL 167
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSAR 466
++DEC +G + +C N PGSY+C C G+ DG +C V+EC + C +
Sbjct: 168 DIDECR---YG-YCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECAT-ENPCVQT-- 220
Query: 467 CVNIDGGFRCEC 478
CVN G C C
Sbjct: 221 CVNTYGSLICRC 232
Score = 65.3 bits (152), Expect = 6e-10
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 8/146 (5%)
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLT--CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
A C+ +C GF D + C D+DEC+ C + CVN GGY+C
Sbjct: 14 ALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIP----EACRGDMMCVNQNGGYLCI 69
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCRCRDGYEGD-GYTCMHVD 452
+ ++ G N P S CR GY+ D C+ VD
Sbjct: 70 PRTNPVYRGPYSNPYSTPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVD 129
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC SH C+ + C+N +GG+ C C
Sbjct: 130 ECATDSHQCNPTQICINTEGGYTCSC 155
>Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 231
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 341
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 271
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 272 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 329
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 330 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 386
Score = 107 bits (256), Expect = 2e-22
Identities = 61/170 (35%), Positives = 77/170 (45%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 395 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 449
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 450 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI GGFRC F
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAF 554
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 317
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 318 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 426
>Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 231
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 341
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 271
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 272 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 329
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 330 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 386
Score = 107 bits (256), Expect = 2e-22
Identities = 61/170 (35%), Positives = 77/170 (45%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 395 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 449
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 450 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI GGFRC F
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAF 554
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 317
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 318 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 426
>X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein.
Length = 683
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 231
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 341
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 271
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 272 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 329
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 330 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 386
Score = 104 bits (250), Expect = 9e-22
Identities = 60/170 (35%), Positives = 76/170 (44%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 395 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 449
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 450 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI G FRC F
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAF 554
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 317
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 318 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 426
>X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein.
Length = 601
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 231
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 341
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 271
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 272 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 329
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 330 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 386
Score = 105 bits (251), Expect = 6e-22
Identities = 64/183 (34%), Positives = 81/183 (44%), Gaps = 21/183 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 395 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 449
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 450 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF--TENCELSC 487
+ C C GY +G C +DEC G H C + C NI G FRC F EN S
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAFECPENYRRSA 564
Query: 488 SWQ 490
+ Q
Sbjct: 565 ATQ 567
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 317
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 318 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 426
>X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein.
Length = 566
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 231
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 341
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 271
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 272 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 329
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 330 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 386
Score = 104 bits (250), Expect = 9e-22
Identities = 60/170 (35%), Positives = 76/170 (44%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 395 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 449
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 450 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI G FRC F
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAF 554
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 317
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 318 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 426
>U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein.
Length = 703
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 231
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 341
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 271
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 272 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 329
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 330 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 386
Score = 104 bits (250), Expect = 9e-22
Identities = 60/170 (35%), Positives = 76/170 (44%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 395 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 449
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 450 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI G FRC F
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAF 554
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 317
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 318 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 426
>BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein.
Length = 683
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 231
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 341
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 271
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 272 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 329
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 330 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 386
Score = 107 bits (256), Expect = 2e-22
Identities = 61/170 (35%), Positives = 77/170 (45%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 395 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 449
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 450 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI GGFRC F
Sbjct: 505 FQCSCPSSGYRLAPNGSNCQDIDECVTGIHNCSINETCFNIQGGFRCLAF 554
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 317
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 318 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 426
>AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein.
Length = 703
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 231
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 341
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 271
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 272 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 329
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 330 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 386
Score = 107 bits (256), Expect = 2e-22
Identities = 61/170 (35%), Positives = 77/170 (45%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 395 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 449
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 450 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI GGFRC F
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAF 554
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 317
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 318 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 426
>AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens
cDNA PSEC0266 fis, clone NT2RP3003649, highly similar to
Homo sapiens fibulin-1D mRNA. ).
Length = 638
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 113 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 166
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 167 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 226
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 227 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 276
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 149 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 206
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 207 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 264
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 265 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 321
Score = 107 bits (256), Expect = 2e-22
Identities = 61/170 (35%), Positives = 77/170 (45%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 330 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 384
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 385 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 439
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI GGFRC F
Sbjct: 440 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAF 489
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 195 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 252
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 253 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 310
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 311 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 361
>AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein.
Length = 495
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 48 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 101
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 102 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 161
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 162 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 211
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 84 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 141
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 142 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 199
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 200 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 256
Score = 107 bits (256), Expect = 2e-22
Identities = 61/170 (35%), Positives = 77/170 (45%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 265 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 319
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 320 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 374
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI GGFRC F
Sbjct: 375 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAF 424
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 130 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 187
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 188 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 245
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 246 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 296
>AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D
precursor protein.
Length = 703
Score = 111 bits (268), Expect = 6e-24
Identities = 56/170 (32%), Positives = 81/170 (47%), Gaps = 17/170 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNT 382
D C G C + C + + C C G+Q DG++C+DV+EC H C
Sbjct: 178 DRCRGGGPCKQQ--CRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGS----HSCRLGE 231
Query: 383 RCVNVVGGYVCQ----CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-- 436
C+N VG + CQ C GY + +C ++DECE H C D +C NT GS+ CR
Sbjct: 232 SCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPK 291
Query: 437 --CRDGYEGDGY-TCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENC 483
C+ G+ D C+ ++EC S C C+N +G + C+ NC
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNC 341
Score = 109 bits (262), Expect = 3e-23
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 21/177 (11%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQ-GDGLTCQDVDECQEAGGLH 374
C V+ C G HSC +C+N + C+ C G++ + +C+D+DEC+ G+H
Sbjct: 214 CEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECES--GIH 271
Query: 375 GHHCHSNTRCVNVVGGYVC----QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+C + C N +G + C QC G+ + NC++++EC + C C NT
Sbjct: 272 --NCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTE 329
Query: 431 GSYTCR-----CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
GSYTC+ C GY +G C+ VDEC + C RCVN G FRCEC T
Sbjct: 330 GSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKT 386
Score = 104 bits (250), Expect = 9e-22
Identities = 60/170 (35%), Positives = 76/170 (44%), Gaps = 19/170 (11%)
Query: 319 KFCPGVDYCNM--GHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLH 374
+ C V+ C G C C N Y C C+ GF+ DG +C+D++EC +
Sbjct: 395 RMCVDVNECQRYPGRLCGHK--CENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSP--- 449
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDK--FNCVEVDECEGNTHGCHADAVCTNTPGS 432
C + C NV G Y C C GY D C ++DEC T G C N PGS
Sbjct: 450 ---C--SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGS 504
Query: 433 YTCRC-RDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
+ C C GY +G C +DEC G H C + C NI G FRC F
Sbjct: 505 FQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGAFRCLAF 554
Score = 95.9 bits (228), Expect = 4e-19
Identities = 57/173 (32%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCK----CNQGFQGDGL-TCQDVDECQEAGGLH 374
C +D C G H+C + C N + C+ C GF D L C D++EC
Sbjct: 260 CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-- 317
Query: 375 GHHCHSNTRCVNVVGGYVCQ-----CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C C+N G Y CQ C GY ++ CV+VDEC C C N
Sbjct: 318 --PCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVN 375
Query: 429 TPGSYTCRCRDGYEGDGYT--CMHVDECTE-GSHTCHHSARCVNIDGGFRCEC 478
+PGS+ C C+ GY DG + C+ V+EC C H +C N G + C C
Sbjct: 376 SPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH--KCENTLGSYLCSC 426
>AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellular
matrix protein protein.
Length = 443
Score = 111 bits (268), Expect = 6e-24
Identities = 59/162 (36%), Positives = 84/162 (51%), Gaps = 17/162 (10%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C H + C NL+ Y C C G++ G C D+DEC+ +C
Sbjct: 121 CVDVDECAQALHDRRPSQDCHNLSGSYQCTCPDGYRKIGPECVDIDECRY------RYCQ 174
Query: 380 SNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
RCVN+ G + CQC G+ + +CV+V+EC+ G + C N+ G++ CRC
Sbjct: 175 H--RCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECD---MGAPCEQRCFNSYGTFLCRCH 229
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GYE DG++C +DEC+ S+ C + RCVN G F C C
Sbjct: 230 QGYELHRDGFSCSDIDECSYSSYLCQY--RCVNEPGRFSCHC 269
Score = 109 bits (263), Expect = 2e-23
Identities = 56/160 (35%), Positives = 81/160 (50%), Gaps = 16/160 (10%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C +D C + C C+NL + C+C GFQ + +C DV+EC G C
Sbjct: 162 CVDIDECRYRY-CQHR--CVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDM-----GAPC 213
Query: 379 HSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
RC N G ++C+C GY +D F+C ++DEC +++ C C N PG ++C C
Sbjct: 214 EQ--RCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYR--CVNEPGRFSCHC 269
Query: 438 RDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY+ C +DEC G+H C + CVN GG+RC
Sbjct: 270 PQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRC 309
Score = 88.2 bits (209), Expect = 8e-17
Identities = 50/146 (34%), Positives = 68/146 (46%), Gaps = 17/146 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGL 359
R C+P Q G + C V+ C+MG C++ C N + C+C+QG++ DG
Sbjct: 185 RCQCEPGFQL---GPNNRSCVDVNECDMGAPCEQR--CFNSYGTFLCRCHQGYELHRDGF 239
Query: 360 TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG 419
+C D+DEC + L C RCVN G + C C GY C ++DECE H
Sbjct: 240 SCSDIDECSYSSYL----CQY--RCVNEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQ 293
Query: 420 CHADAVCTNTPGSYTC----RCRDGY 441
C C N G Y C RC + Y
Sbjct: 294 CSEAQTCVNFHGGYRCVDTNRCVEPY 319
Score = 79.8 bits (188), Expect = 3e-14
Identities = 48/132 (36%), Positives = 66/132 (50%), Gaps = 15/132 (11%)
Query: 350 CNQGFQGDGL-TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C G++ D +C DVDEC +A LH + C N+ G Y C C GY RK CV
Sbjct: 109 CPPGYEPDDQDSCVDVDECAQA--LHDR--RPSQDCHNLSGSYQCTCPDGY-RKIGPECV 163
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMHVDECTEGSHTCHHSAR 466
++DEC + C N PGS+ C+C G++ + +C+ V+EC G+ C R
Sbjct: 164 DIDECRYR----YCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGA-PCEQ--R 216
Query: 467 CVNIDGGFRCEC 478
C N G F C C
Sbjct: 217 CFNSYGTFLCRC 228
Score = 49.6 bits (113), Expect = 3e-05
Identities = 38/136 (27%), Positives = 53/136 (38%), Gaps = 23/136 (16%)
Query: 346 YTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD 403
YT +C G++ D C+DV+EC C +C+N GGY+C D
Sbjct: 36 YT-ECTDGYEWDPDSQHCRDVNECLTIP----EACKGEMKCINHYGGYLCLPRSAAVIND 90
Query: 404 KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY-TCMHVDECTEGSHTCH 462
HG P + C GYE D +C+ VDEC + H
Sbjct: 91 -------------LHG--EGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDRR 135
Query: 463 HSARCVNIDGGFRCEC 478
S C N+ G ++C C
Sbjct: 136 PSQDCHNLSGSYQCTC 151
Score = 40.7 bits (91), Expect = 0.016
Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 3/49 (6%)
Query: 430 PGSYTCRCRDGYEGD--GYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
P SYT C DGYE D C V+EC C +C+N GG+ C
Sbjct: 33 PDSYT-ECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLC 80
>Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein.
Length = 1821
Score = 111 bits (267), Expect = 7e-24
Identities = 91/295 (30%), Positives = 117/295 (39%), Gaps = 29/295 (9%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVEC-DRAECKNPVLHP-GEC 253
++C C G T C C G I R C D EC++P P G C
Sbjct: 926 QECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRC 985
Query: 254 CPT-CLRQCLLWGNLY--EHGERFAPKEC-AECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
+ CL Y + G EC VC G +CT ++ C C+ Q
Sbjct: 986 VNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG--KCTNLEGSFRC---SCE--Q 1038
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK-CNQGF--QGDGLTCQDVDE 366
+ V + K C VD C SC C+N + C C G+ DG C+D+DE
Sbjct: 1039 GYEVTSD-EKGCQDVDECASRASC-PTGLCLNTEGSFACSACENGYWVNEDGTACEDLDE 1096
Query: 367 CQEAGGLHGHHCHSNTRCVNVVGGYVCQ-CLGGYTRKD-KFNCVEVDECEGNTHGCHADA 424
C G C S C N G + C+ C GGY +C +VDECE C
Sbjct: 1097 CAFPG-----VCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC-LGG 1149
Query: 425 VCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C NT GSY C C G++ +G C V+EC H H C+N G F C C
Sbjct: 1150 ECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPH-GECLNSHGSFFCLC 1203
Score = 109 bits (263), Expect = 2e-23
Identities = 63/183 (34%), Positives = 88/183 (48%), Gaps = 21/183 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGD 357
R C P Q P + +C + C + C C+N Y+C C G+ G
Sbjct: 869 RCVCSPGYQLH-PSQA--YCTDDNEC-LRDPCQGKGRCINRVGSYSCFCYPGYTLATSGA 924
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
CQD++EC++ G G +C N G Y C+C GY K +C +++EC
Sbjct: 925 TQECQDINECEQPGVCSGG------QCTNTEGSYHCECDQGYIMVRKGHCQDINEC--RH 976
Query: 418 HGCHADAVCTNTPGSYTC-RCRDGYEGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
G D C N+PGSYTC C +GY G +C+ V+EC T G C H +C N++G FR
Sbjct: 977 PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPG--VCAH-GKCTNLEGSFR 1033
Query: 476 CEC 478
C C
Sbjct: 1034 CSC 1036
Score = 96.7 bits (230), Expect = 2e-19
Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 13/167 (7%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHC 378
C VD C C C+N + C C GFQ + C D+DEC++ +G
Sbjct: 1216 CQDVDECATTDPC-VGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECED----YGDPV 1270
Query: 379 HSNTRCVNVVGGYVCQ--CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
+C N G Y C C G+ +C+++DEC +T C + C NT GS+ C
Sbjct: 1271 CGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM-CGSHGFCDNTDGSFRCL 1329
Query: 437 CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTE 481
C G+E G+ C+ V+EC C +A C N++G F C C ++
Sbjct: 1330 CDQGFEISPSGWDCVDVNECELMLAVC-GAALCENVEGSFLCLCASD 1375
Score = 93.9 bits (223), Expect = 2e-18
Identities = 88/289 (30%), Positives = 120/289 (41%), Gaps = 44/289 (15%)
Query: 220 DCNRCSCVHG-EITCRPVEC-DRAEC-KNPVLHPGECCPTC-LRQCLLWGNLYEHGERFA 275
D RC C G ++ C D EC ++P G C C + Y A
Sbjct: 866 DGYRCVCSPGYQLHPSQAYCTDDNECLRDPCQGKGRCINRVGSYSCFCYPG-YTLATSGA 924
Query: 276 PKECA---EC----VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN 328
+EC EC VC G QCT + C CD G C ++ C
Sbjct: 925 TQECQDINECEQPGVCSGG--QCTNTEGSYHCE---CDQGYIMVRKGHC----QDINECR 975
Query: 329 MGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGL-HGHHCHSNTRCVN 386
+C + C+N YTC C +G++G +C DV+EC G HG +C N
Sbjct: 976 HPGTCPDGR-CVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-------KCTN 1027
Query: 387 VVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-CRDGY--E 442
+ G + C C GY D+ C +VDEC C +C NT GS+ C C +GY
Sbjct: 1028 LEGSFRCSCEQGYEVTSDEKGCQDVDECASRA-SCPT-GLCLNTEGSFACSACENGYWVN 1085
Query: 443 GDGYTCMHVDECT-EG---SHTCHHSA---RCVNIDGGFRCECFTENCE 484
DG C +DEC G S C ++A C + DGG+R ++CE
Sbjct: 1086 EDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE 1134
Score = 93.5 bits (222), Expect = 2e-18
Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 24/210 (11%)
Query: 278 ECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA C G C + AC C+ + G C+ +D C C +
Sbjct: 1054 ECASRASCPTG--LCLNTEGSFACSA--CENGYWVNEDGTACE---DLDECAFPGVCP-S 1105
Query: 337 ATCMNLNTKYTCK-CNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N ++CK C+ G++ L +C+DVDEC++ C C N VG Y C
Sbjct: 1106 GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQS----SCLGG-ECKNTVGSYQC 1160
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EGDGYTCMH 450
C G+ + C +V+EC G H C C N+ GS+ C C G+ EG G +C
Sbjct: 1161 LCPQGFQLANGTVCEDVNECMGEEH-CAPHGECLNSHGSFFCLCAPGFVSAEG-GTSCQD 1218
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFT 480
VDEC + C CVN +G F C C T
Sbjct: 1219 VDECAT-TDPC-VGGHCVNTEGSFNCLCET 1246
Score = 90.2 bits (214), Expect = 2e-17
Identities = 59/164 (35%), Positives = 74/164 (45%), Gaps = 21/164 (12%)
Query: 322 PGVDYCNMGHS--CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
PG+D C G + C TC+NL Y C C+ G+Q C D +EC
Sbjct: 843 PGIDRCAAGATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR------DP 895
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDK---FNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
C RC+N VG Y C C GYT C +++ECE G + CTNT GSY
Sbjct: 896 CQGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECE--QPGVCSGGQCTNTEGSYH 953
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY G+ C ++EC TC RCVN G + C
Sbjct: 954 CECDQGYIMVRKGH-CQDINECRHPG-TC-PDGRCVNSPGSYTC 994
Score = 55.6 bits (128), Expect = 5e-07
Identities = 40/127 (31%), Positives = 53/127 (41%), Gaps = 11/127 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCK--CNQGFQ-GDGLTCQDVDECQEAGGLHGH 376
C +D C + G C N Y C C GF C D+DEC +
Sbjct: 1257 CVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECA-----NDT 1311
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C S+ C N G + C C G+ ++CV+V+ECE C A A+C N GS+ C
Sbjct: 1312 MCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGA-ALCENVEGSFLC 1370
Query: 436 RCRDGYE 442
C E
Sbjct: 1371 LCASDLE 1377
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/75 (37%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRC 384
C + + C EN C+ + YTC C +GFQ D + C DV+EC + G H C
Sbjct: 1737 CGILNGC-ENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG--YC 1793
Query: 385 VNVVGGYVCQCLGGY 399
N G Y C C GY
Sbjct: 1794 ENTEGSYRCHCSPGY 1808
Score = 53.6 bits (123), Expect = 2e-06
Identities = 32/80 (40%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECE---GNTHGCH 421
+ +E G L+G C N RCV V GY C C G+ CV+V+EC+ G C
Sbjct: 1733 QAEECGILNG--CE-NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLC- 1788
Query: 422 ADAVCTNTPGSYTCRCRDGY 441
C NT GSY C C GY
Sbjct: 1789 VHGYCENTEGSYRCHCSPGY 1808
Score = 49.6 bits (113), Expect = 3e-05
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 17/132 (12%)
Query: 269 EHGERFAPKECAEC---VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVD 325
E GE EC + VC G +C C L C P + G+C +D
Sbjct: 1253 ESGECVDIDECEDYGDPVC--GTWKCENSPGSYRCV-LGCQPGFHMAPNGDCID----ID 1305
Query: 326 YCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTR 383
C C + C N + + C C+QGF+ G C DV+EC+ + G
Sbjct: 1306 ECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCG-----AAL 1360
Query: 384 CVNVVGGYVCQC 395
C NV G ++C C
Sbjct: 1361 CENVEGSFLCLC 1372
Score = 48.8 bits (111), Expect = 6e-05
Identities = 39/125 (31%), Positives = 49/125 (39%), Gaps = 18/125 (14%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLH 374
G+ C CP D C + + +T F T D DEC +
Sbjct: 1445 GDACDLCPSEDSAEFSEICPSGKGYIPVEGAWT------FGQTMYT--DADECV----IF 1492
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGG--YTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS 432
G N RC+N V GYVC C G Y K C + DEC+ C + C NT GS
Sbjct: 1493 GPGLCPNGRCLNTVPGYVCLCNPGFHYDASHK-KCEDHDECQ--DLACE-NGECVNTEGS 1548
Query: 433 YTCRC 437
+ C C
Sbjct: 1549 FHCFC 1553
Score = 45.6 bits (103), Expect = 6e-04
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 8/79 (10%)
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCMHVDECTE---GSH 459
F ++ +EC G +GC + C YTC C +G++ D C+ V+EC + +
Sbjct: 1729 FEGLQAEEC-GILNGCE-NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAV 1786
Query: 460 TCHHSARCVNIDGGFRCEC 478
C H C N +G +RC C
Sbjct: 1787 LCVH-GYCENTEGSYRCHC 1804
Score = 45.2 bits (102), Expect = 7e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
+C GY R + +C +++EC T G DA C NT GSY C CR G
Sbjct: 607 ECPQGYKRLNLTHCQDINECL--TLGLCKDAECVNTRGSYLCTCRPG 651
Score = 43.6 bits (98), Expect = 0.002
Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 6/73 (8%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE---GDGYTCMHVDECTEGSHTCHHSAR 466
+D C C N P Y C C GY+ Y C +EC C R
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAY-CTDDNECLR--DPCQGKGR 901
Query: 467 CVNIDGGFRCECF 479
C+N G + C C+
Sbjct: 902 CINRVGSYSCFCY 914
Score = 42.7 bits (96), Expect = 0.004
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 5/72 (6%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEGSHTCHHSAR 466
+ DEC G + C NT Y C C G Y+ C DEC + C +
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD--LAC-ENGE 1541
Query: 467 CVNIDGGFRCEC 478
CVN +G F C C
Sbjct: 1542 CVNTEGSFHCFC 1553
Score = 36.7 bits (81), Expect = 0.26
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 7/51 (13%)
Query: 349 KCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+C QG++ LT CQD++EC G C + CVN G Y+C C G
Sbjct: 607 ECPQGYKRLNLTHCQDINECLTLG-----LC-KDAECVNTRGSYLCTCRPG 651
>S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growth
factor-beta-binding protein-2 protein.
Length = 1821
Score = 111 bits (267), Expect = 7e-24
Identities = 91/295 (30%), Positives = 117/295 (39%), Gaps = 29/295 (9%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVEC-DRAECKNPVLHP-GEC 253
++C C G T C C G I R C D EC++P P G C
Sbjct: 926 QECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRC 985
Query: 254 CPT-CLRQCLLWGNLY--EHGERFAPKEC-AECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
+ CL Y + G EC VC G +CT ++ C C+ Q
Sbjct: 986 VNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG--KCTNLEGSFRC---SCE--Q 1038
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK-CNQGF--QGDGLTCQDVDE 366
+ V + K C VD C SC C+N + C C G+ DG C+D+DE
Sbjct: 1039 GYEVTSD-EKGCQDVDECASRASC-PTGLCLNTEGSFACSACENGYWVNEDGTACEDLDE 1096
Query: 367 CQEAGGLHGHHCHSNTRCVNVVGGYVCQ-CLGGYTRKD-KFNCVEVDECEGNTHGCHADA 424
C G C S C N G + C+ C GGY +C +VDECE C
Sbjct: 1097 CAFPG-----VCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC-LGG 1149
Query: 425 VCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C NT GSY C C G++ +G C V+EC H H C+N G F C C
Sbjct: 1150 ECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPH-GECLNSHGSFFCLC 1203
Score = 109 bits (262), Expect = 3e-23
Identities = 63/183 (34%), Positives = 88/183 (48%), Gaps = 21/183 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGD 357
R C P Q P + +C + C + C C+N Y+C C G+ G
Sbjct: 869 RCVCSPGYQLH-PSQA--YCTDDNEC-LRDPCKGKGRCINRVGSYSCFCYPGYTLATSGA 924
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
CQD++EC++ G G +C N G Y C+C GY K +C +++EC
Sbjct: 925 TQECQDINECEQPGVCSGG------QCTNTEGSYHCECDQGYIMVRKGHCQDINEC--RH 976
Query: 418 HGCHADAVCTNTPGSYTC-RCRDGYEGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
G D C N+PGSYTC C +GY G +C+ V+EC T G C H +C N++G FR
Sbjct: 977 PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPG--VCAH-GKCTNLEGSFR 1033
Query: 476 CEC 478
C C
Sbjct: 1034 CSC 1036
Score = 96.7 bits (230), Expect = 2e-19
Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 13/167 (7%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHC 378
C VD C C C+N + C C GFQ + C D+DEC++ +G
Sbjct: 1216 CQDVDECATTDPC-VGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECED----YGDPV 1270
Query: 379 HSNTRCVNVVGGYVCQ--CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
+C N G Y C C G+ +C+++DEC +T C + C NT GS+ C
Sbjct: 1271 CGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM-CGSHGFCDNTDGSFRCL 1329
Query: 437 CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTE 481
C G+E G+ C+ V+EC C +A C N++G F C C ++
Sbjct: 1330 CDQGFEISPSGWDCVDVNECELMLAVC-GAALCENVEGSFLCLCASD 1375
Score = 93.9 bits (223), Expect = 2e-18
Identities = 88/289 (30%), Positives = 120/289 (41%), Gaps = 44/289 (15%)
Query: 220 DCNRCSCVHG-EITCRPVEC-DRAEC-KNPVLHPGECCPTC-LRQCLLWGNLYEHGERFA 275
D RC C G ++ C D EC ++P G C C + Y A
Sbjct: 866 DGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPG-YTLATSGA 924
Query: 276 PKECA---EC----VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN 328
+EC EC VC G QCT + C CD G C ++ C
Sbjct: 925 TQECQDINECEQPGVCSGG--QCTNTEGSYHCE---CDQGYIMVRKGHC----QDINECR 975
Query: 329 MGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGL-HGHHCHSNTRCVN 386
+C + C+N YTC C +G++G +C DV+EC G HG +C N
Sbjct: 976 HPGTCPDGR-CVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-------KCTN 1027
Query: 387 VVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-CRDGY--E 442
+ G + C C GY D+ C +VDEC C +C NT GS+ C C +GY
Sbjct: 1028 LEGSFRCSCEQGYEVTSDEKGCQDVDECASRA-SCPT-GLCLNTEGSFACSACENGYWVN 1085
Query: 443 GDGYTCMHVDECT-EG---SHTCHHSA---RCVNIDGGFRCECFTENCE 484
DG C +DEC G S C ++A C + DGG+R ++CE
Sbjct: 1086 EDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE 1134
Score = 93.5 bits (222), Expect = 2e-18
Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 24/210 (11%)
Query: 278 ECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA C G C + AC C+ + G C+ +D C C +
Sbjct: 1054 ECASRASCPTG--LCLNTEGSFACSA--CENGYWVNEDGTACE---DLDECAFPGVCP-S 1105
Query: 337 ATCMNLNTKYTCK-CNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N ++CK C+ G++ L +C+DVDEC++ C C N VG Y C
Sbjct: 1106 GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQS----SCLGG-ECKNTVGSYQC 1160
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EGDGYTCMH 450
C G+ + C +V+EC G H C C N+ GS+ C C G+ EG G +C
Sbjct: 1161 LCPQGFQLANGTVCEDVNECMGEEH-CAPHGECLNSHGSFFCLCAPGFVSAEG-GTSCQD 1218
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFT 480
VDEC + C CVN +G F C C T
Sbjct: 1219 VDECAT-TDPC-VGGHCVNTEGSFNCLCET 1246
Score = 89.8 bits (213), Expect = 3e-17
Identities = 59/164 (35%), Positives = 74/164 (45%), Gaps = 21/164 (12%)
Query: 322 PGVDYCNMGHS--CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
PG+D C G + C TC+NL Y C C+ G+Q C D +EC
Sbjct: 843 PGIDRCAAGATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR------DP 895
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDK---FNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
C RC+N VG Y C C GYT C +++ECE G + CTNT GSY
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECE--QPGVCSGGQCTNTEGSYH 953
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY G+ C ++EC TC RCVN G + C
Sbjct: 954 CECDQGYIMVRKGH-CQDINECRHPG-TC-PDGRCVNSPGSYTC 994
Score = 55.6 bits (128), Expect = 5e-07
Identities = 40/127 (31%), Positives = 53/127 (41%), Gaps = 11/127 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCK--CNQGFQ-GDGLTCQDVDECQEAGGLHGH 376
C +D C + G C N Y C C GF C D+DEC +
Sbjct: 1257 CVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECA-----NDT 1311
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C S+ C N G + C C G+ ++CV+V+ECE C A A+C N GS+ C
Sbjct: 1312 MCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGA-ALCENVEGSFLC 1370
Query: 436 RCRDGYE 442
C E
Sbjct: 1371 LCASDLE 1377
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/75 (37%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRC 384
C + + C EN C+ + YTC C +GFQ D + C DV+EC + G H C
Sbjct: 1737 CGILNGC-ENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG--YC 1793
Query: 385 VNVVGGYVCQCLGGY 399
N G Y C C GY
Sbjct: 1794 ENTEGSYRCHCSPGY 1808
Score = 53.6 bits (123), Expect = 2e-06
Identities = 32/80 (40%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECE---GNTHGCH 421
+ +E G L+G C N RCV V GY C C G+ CV+V+EC+ G C
Sbjct: 1733 QAEECGILNG--CE-NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLC- 1788
Query: 422 ADAVCTNTPGSYTCRCRDGY 441
C NT GSY C C GY
Sbjct: 1789 VHGYCENTEGSYRCHCSPGY 1808
Score = 49.6 bits (113), Expect = 3e-05
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 17/132 (12%)
Query: 269 EHGERFAPKECAEC---VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVD 325
E GE EC + VC G +C C L C P + G+C +D
Sbjct: 1253 ESGECVDIDECEDYGDPVC--GTWKCENSPGSYRCV-LGCQPGFHMAPNGDCID----ID 1305
Query: 326 YCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTR 383
C C + C N + + C C+QGF+ G C DV+EC+ + G
Sbjct: 1306 ECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCG-----AAL 1360
Query: 384 CVNVVGGYVCQC 395
C NV G ++C C
Sbjct: 1361 CENVEGSFLCLC 1372
Score = 48.8 bits (111), Expect = 6e-05
Identities = 39/125 (31%), Positives = 49/125 (39%), Gaps = 18/125 (14%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLH 374
G+ C CP D C + + +T F T D DEC +
Sbjct: 1445 GDACDLCPSEDSAEFSEICPSGKGYIPVEGAWT------FGQTMYT--DADECV----IF 1492
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGG--YTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS 432
G N RC+N V GYVC C G Y K C + DEC+ C + C NT GS
Sbjct: 1493 GPGLCPNGRCLNTVPGYVCLCNPGFHYDASHK-KCEDHDECQ--DLACE-NGECVNTEGS 1548
Query: 433 YTCRC 437
+ C C
Sbjct: 1549 FHCFC 1553
Score = 45.6 bits (103), Expect = 6e-04
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 8/79 (10%)
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCMHVDECTE---GSH 459
F ++ +EC G +GC + C YTC C +G++ D C+ V+EC + +
Sbjct: 1729 FEGLQAEEC-GILNGCE-NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAV 1786
Query: 460 TCHHSARCVNIDGGFRCEC 478
C H C N +G +RC C
Sbjct: 1787 LCVH-GYCENTEGSYRCHC 1804
Score = 45.2 bits (102), Expect = 7e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
+C GY R + +C +++EC T G DA C NT GSY C CR G
Sbjct: 607 ECPQGYKRLNLTHCQDINECL--TLGLCKDAECVNTRGSYLCTCRPG 651
Score = 43.2 bits (97), Expect = 0.003
Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 6/73 (8%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE---GDGYTCMHVDECTEGSHTCHHSAR 466
+D C C N P Y C C GY+ Y C +EC C R
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAY-CTDDNECLR--DPCKGKGR 901
Query: 467 CVNIDGGFRCECF 479
C+N G + C C+
Sbjct: 902 CINRVGSYSCFCY 914
Score = 42.7 bits (96), Expect = 0.004
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 5/72 (6%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEGSHTCHHSAR 466
+ DEC G + C NT Y C C G Y+ C DEC + C +
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD--LAC-ENGE 1541
Query: 467 CVNIDGGFRCEC 478
CVN +G F C C
Sbjct: 1542 CVNTEGSFHCFC 1553
Score = 36.7 bits (81), Expect = 0.26
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 7/51 (13%)
Query: 349 KCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+C QG++ LT CQD++EC G C + CVN G Y+C C G
Sbjct: 607 ECPQGYKRLNLTHCQDINECLTLG-----LC-KDAECVNTRGSYLCTCRPG 651
>D87433-1|BAA13377.2| 2589|Homo sapiens KIAA0246 protein protein.
Length = 2589
Score = 111 bits (267), Expect = 7e-24
Identities = 75/226 (33%), Positives = 102/226 (45%), Gaps = 24/226 (10%)
Query: 261 CLLWGNLYEHGERFAPKECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
C + N +HGE +C E C C G R C + C P FS G C
Sbjct: 786 CHICSNPNKHGE-----QCQEDCGCVHGLCD-NRPGSGGVCQQGTCAPG--FS--GRFCN 835
Query: 320 FCPG-VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQ--EAGGLHGH 376
G + C +A C++ C+C GF+GDG +C + C + GG
Sbjct: 836 ESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGG---- 891
Query: 377 HCHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG-CHADAVCTNT-PGSY 433
C N CV +G + C C G++ + CV +DECE + G CH DA+C+ PG
Sbjct: 892 -CSENAECVPGSLGTHHCTCHKGWSGDGRV-CVAIDECELDVRGGCHTDALCSYVGPGQS 949
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
C C+ G+ GDGY C +D C G+ CH A C + GG R C C
Sbjct: 950 RCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTC 995
Score = 99 bits (238), Expect = 2e-20
Identities = 56/154 (36%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 333 CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH-CHSNTRCVNVVGG 390
CD NA C+ + TC C G+ G+G+ C +VD C HGH C + C V G
Sbjct: 1443 CDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCA-----HGHGGCSPHANCTKVAPG 1497
Query: 391 Y-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGY-T 447
C C GY + C E++ C + GCH A C T P +C CR+GY GDG T
Sbjct: 1498 QRTCTCQDGYMGDGEL-CQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1556
Query: 448 CMHVDECTEGSHTCHHSARCVNI-DGGFRCECFT 480
C +D C++ + C A C + DG C C T
Sbjct: 1557 CELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDT 1590
Score = 91.1 bits (216), Expect = 1e-17
Identities = 62/187 (33%), Positives = 80/187 (42%), Gaps = 25/187 (13%)
Query: 282 CVCHDGNMQCTRVDPELACPRLP--CDPPQ---QFSVPGECCK----------FCPGVDY 326
CVC+ G Q R D ++ P+ P CDP Q S C FC VD
Sbjct: 1419 CVCNVG-WQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDP 1477
Query: 327 CNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C GH C +A C + + TC C G+ GDG CQ+++ C +H CH + C
Sbjct: 1478 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCL----IHHGGCHIHAEC 1533
Query: 385 VNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYE 442
+ V C C GY+ C +D C N GC A C +T G TC C +
Sbjct: 1534 IPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHT 1593
Query: 443 -GDGYTC 448
GDG TC
Sbjct: 1594 VGDGLTC 1600
Score = 83.8 bits (198), Expect = 2e-15
Identities = 53/151 (35%), Positives = 63/151 (41%), Gaps = 17/151 (11%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C GV C+ H C E L +C CN G+QG L C + C
Sbjct: 1398 CTGV--CDCAHGLCQEG-----LQGDGSCVCNVGWQG--LRCDQKITSPQCP----RKCD 1444
Query: 380 SNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRC 437
N CV + G C C GY+ F C EVD C GC A CT PG TC C
Sbjct: 1445 PNANCVQDSAGASTCACAAGYSGNGIF-CSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1503
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCV 468
+DGY GDG C ++ C CH A C+
Sbjct: 1504 QDGYMGDGELCQEINSCLIHHGGCHIHAECI 1534
Score = 82.2 bits (194), Expect = 5e-15
Identities = 72/253 (28%), Positives = 98/253 (38%), Gaps = 38/253 (15%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVE---CDRAECKNPVLHPGECCPTCLR 259
+C+ + G Q DC CVHG RP C + C G C +
Sbjct: 785 ACHICSNPNKHGEQCQEDCG---CVHGLCDNRPGSGGVCQQGTCAPG--FSGRFCNESMG 839
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
C G L +H A CV +G +C +D C P S P
Sbjct: 840 DCGPTG-LAQHCHLH-----ARCVSQEGVARCRCLD-GFEGDGFSCTPSNPCSHPDR--- 889
Query: 320 FCPGVDYCNMGHSCDENATCM--NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
C ENA C+ +L T + C C++G+ GDG C +DEC+ + G
Sbjct: 890 -----------GGCSENAECVPGSLGTHH-CTCHKGWSGDGRVCVAIDECEL--DVRG-G 934
Query: 378 CHSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY-TC 435
CH++ C V G C C G+ D + C +D C GCH A C G C
Sbjct: 935 CHTDALCSYVGPGQSRCTCKLGFA-GDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVC 993
Query: 436 RCRDGYEGDGYTC 448
C G+ GDG++C
Sbjct: 994 TCPPGFGGDGFSC 1006
Score = 77.4 bits (182), Expect = 1e-13
Identities = 47/145 (32%), Positives = 64/145 (44%), Gaps = 15/145 (10%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C A C N+ C+C+ G++GDG C D CQ+ HG C + C V
Sbjct: 2083 CAPEAVCRAGNS---CECSLGYEGDGRVCTVADLCQDG---HGG-CSEHANCSQVGTMVT 2135
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDGYTCMH 450
C CL Y D ++C + C +G+ GC A C +T + C C GY GDG C+
Sbjct: 2136 CTCLPDY-EGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLE 2194
Query: 451 -----VDECTEGSHTCHHSARCVNI 470
VD C CH A C ++
Sbjct: 2195 ESEPPVDRCLGQPPPCHSDAMCTDL 2219
Score = 73.7 bits (173), Expect = 2e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 11/117 (9%)
Query: 319 KFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
+ C D C GH C E+A C + T TC C ++GDG +C+ + C + H
Sbjct: 2106 RVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDG---HRGG 2162
Query: 378 CHSNTRCVNV-VGGYVCQCLGGYTRKDKFNCVE-----VDECEGNTHGCHADAVCTN 428
C + C++ + C+C GY D C+E VD C G CH+DA+CT+
Sbjct: 2163 CSEHANCLSTGLNTRRCECHAGYVG-DGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2218
Score = 64.1 bits (149), Expect = 1e-09
Identities = 52/175 (29%), Positives = 70/175 (40%), Gaps = 25/175 (14%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C + CM+ ++ C C GF G C+ C A G
Sbjct: 1984 GSECQACPG----GPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTA--CE---LC--APGA 2032
Query: 374 HGHHCHS-----NTRCVNVVGGY-VCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVC 426
G HC + + RC +GG C C G+T C V+++ T C +AVC
Sbjct: 2033 FGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGP---RCEVQLELQPVCTPPCAPEAVC 2089
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTE 481
+C C GYEGDG C D C +G C A C + C C +
Sbjct: 2090 R---AGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPD 2141
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/170 (28%), Positives = 68/170 (40%), Gaps = 16/170 (9%)
Query: 315 GECCKFC-PGV--DYCNMGHSCDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEA 370
G C+ C PG +C C + C L +C C++G+ G C+ E Q
Sbjct: 2022 GTACELCAPGAFGPHCQACR-CTVHGRCDEGLGGSGSCFCDEGWTGP--RCEVQLELQP- 2077
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+ C C G C+C GY + C D C+ GC A C+
Sbjct: 2078 --VCTPPCAPEAVCR---AGNSCECSLGYEGDGRV-CTVADLCQDGHGGCSEHANCSQVG 2131
Query: 431 GSYTCRCRDGYEGDGYTCMHVDECTEGSH-TCHHSARCVNID-GGFRCEC 478
TC C YEGDG++C + CT+G C A C++ RCEC
Sbjct: 2132 TMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCEC 2181
Score = 59.7 bits (138), Expect = 3e-08
Identities = 48/173 (27%), Positives = 68/173 (39%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG +G C + C + C C++GF G T +V E G
Sbjct: 1345 GTLCEPCPG----GLGGVCSGHGQCQDRFLGSGECHCHEGFHG---TACEVCEL----GR 1393
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCT 427
+G +C C + + G C C G+ + +C C +A C
Sbjct: 1394 YGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRK---CDPNANCV 1450
Query: 428 -NTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
++ G+ TC C GY G+G C VD C G C A C + G R C C
Sbjct: 1451 QDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1503
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKY------TCKCNQGFQGDGLTCQDVDECQ 368
G C+ C D G C +C++ + +C C G+ G Q++ CQ
Sbjct: 163 GSACQECQ--DPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCD-QELPVCQ 219
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTN 428
E C NT+C C+CL GYT++ C + C + C A C+
Sbjct: 220 EL------RCPQNTQCSAEAPS--CRCLPGYTQQGS-ECRAPNPCWPSP--CSLLAQCSV 268
Query: 429 TP-GSYTCRCRDGYEGDGYTCMHVDECTEGSHTC-HHSARCV-NIDGGFRCEC 478
+P G C C + Y GDG C+ D CT+ C +S CV G C C
Sbjct: 269 SPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTC 321
Score = 57.6 bits (133), Expect = 1e-07
Identities = 84/343 (24%), Positives = 113/343 (32%), Gaps = 39/343 (11%)
Query: 130 LFKGALQEVRLVSGPHGYLAQCPGLDSE-CPTCGQFALLQATVQELTTHIHDLSLKLVGA 188
LFKG +V+ H C + + CP+ L Q+ + L +V
Sbjct: 47 LFKGC--DVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQ-LGGSMVSM 103
Query: 189 EARISRLEQCDCQKSC---YSNGTVHADGATWQRDCN-RCSCVHG---EITCRPVECDRA 241
+ + QK+C Y H + CN +C+ G TC E R
Sbjct: 104 SGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRG 163
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPEL-AC 300
P P C C + HG P+ C+C G D EL C
Sbjct: 164 SACQECQDPNRFGPDCQSVCSCVHGVCNHG----PRGDGSCLCFAGYTG-PHCDQELPVC 218
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC------------MNLNTKYTC 348
L C Q S C+ PG Y G C C ++ + C
Sbjct: 219 QELRCPQNTQCSAEAPSCRCLPG--YTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQC 276
Query: 349 KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN-TRCVNVVGGYV-CQCLGGYTRKDKFN 406
C + + GDG+ C D C + L G C SN T CV G C C G + N
Sbjct: 277 HCPENYHGDGMVCLPKDPCTD--NLGG--CPSNSTLCVYQKPGQAFCTCRPGLVSINS-N 331
Query: 407 CVEVDECEGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDGYTC 448
+ C A C T G +C CR+ GDG C
Sbjct: 332 ASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRAC 374
Score = 56.4 bits (130), Expect = 3e-07
Identities = 56/199 (28%), Positives = 75/199 (37%), Gaps = 38/199 (19%)
Query: 317 CCK--FCPGVDYCNMGHS--CDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAG 371
CCK F P C G S C C + + C C ++G + C +
Sbjct: 739 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKG--IACHICSNPNK-- 794
Query: 372 GLHGHHCHSNTRCVNVV------GGYVCQ---CLGGYTRKDKFNCVEVDEC--EGNTHGC 420
HG C + CV+ + G VCQ C G++ +F + +C G C
Sbjct: 795 --HGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS--GRFCNESMGDCGPTGLAQHC 850
Query: 421 HADAVCTNTPGSYTCRCRDGYEGDGYTCM------HVD--------ECTEGSHTCHHSAR 466
H A C + G CRC DG+EGDG++C H D EC GS HH
Sbjct: 851 HLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTC 910
Query: 467 CVNIDGGFRCECFTENCEL 485
G R + CEL
Sbjct: 911 HKGWSGDGRVCVAIDECEL 929
>DQ786774-1|ABG91068.1| 2570|Homo sapiens FEX1 protein.
Length = 2570
Score = 111 bits (267), Expect = 7e-24
Identities = 75/226 (33%), Positives = 102/226 (45%), Gaps = 24/226 (10%)
Query: 261 CLLWGNLYEHGERFAPKECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
C + N +HGE +C E C C G R C + C P FS G C
Sbjct: 767 CHICSNPNKHGE-----QCQEDCGCVHGLCD-NRPGSGGVCQQGTCAPG--FS--GRFCN 816
Query: 320 FCPG-VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQ--EAGGLHGH 376
G + C +A C++ C+C GF+GDG +C + C + GG
Sbjct: 817 ESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGG---- 872
Query: 377 HCHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG-CHADAVCTNT-PGSY 433
C N CV +G + C C G++ + CV +DECE + G CH DA+C+ PG
Sbjct: 873 -CSENAECVPGSLGTHHCTCHKGWSGDGRV-CVAIDECELDVRGGCHTDALCSYVGPGQS 930
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
C C+ G+ GDGY C +D C G+ CH A C + GG R C C
Sbjct: 931 RCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTC 976
Score = 99 bits (238), Expect = 2e-20
Identities = 56/154 (36%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 333 CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH-CHSNTRCVNVVGG 390
CD NA C+ + TC C G+ G+G+ C +VD C HGH C + C V G
Sbjct: 1424 CDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCA-----HGHGGCSPHANCTKVAPG 1478
Query: 391 Y-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGY-T 447
C C GY + C E++ C + GCH A C T P +C CR+GY GDG T
Sbjct: 1479 QRTCTCQDGYMGDGEL-CQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1537
Query: 448 CMHVDECTEGSHTCHHSARCVNI-DGGFRCECFT 480
C +D C++ + C A C + DG C C T
Sbjct: 1538 CELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDT 1571
Score = 91.1 bits (216), Expect = 1e-17
Identities = 62/187 (33%), Positives = 80/187 (42%), Gaps = 25/187 (13%)
Query: 282 CVCHDGNMQCTRVDPELACPRLP--CDPPQ---QFSVPGECCK----------FCPGVDY 326
CVC+ G Q R D ++ P+ P CDP Q S C FC VD
Sbjct: 1400 CVCNVG-WQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDP 1458
Query: 327 CNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C GH C +A C + + TC C G+ GDG CQ+++ C +H CH + C
Sbjct: 1459 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCL----IHHGGCHIHAEC 1514
Query: 385 VNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYE 442
+ V C C GY+ C +D C N GC A C +T G TC C +
Sbjct: 1515 IPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHT 1574
Query: 443 -GDGYTC 448
GDG TC
Sbjct: 1575 VGDGLTC 1581
Score = 83.8 bits (198), Expect = 2e-15
Identities = 53/151 (35%), Positives = 63/151 (41%), Gaps = 17/151 (11%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C GV C+ H C E L +C CN G+QG L C + C
Sbjct: 1379 CTGV--CDCAHGLCQEG-----LQGDGSCVCNVGWQG--LRCDQKITSPQCP----RKCD 1425
Query: 380 SNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRC 437
N CV + G C C GY+ F C EVD C GC A CT PG TC C
Sbjct: 1426 PNANCVQDSAGASTCACAAGYSGNGIF-CSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1484
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCV 468
+DGY GDG C ++ C CH A C+
Sbjct: 1485 QDGYMGDGELCQEINSCLIHHGGCHIHAECI 1515
Score = 82.2 bits (194), Expect = 5e-15
Identities = 72/253 (28%), Positives = 98/253 (38%), Gaps = 38/253 (15%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVE---CDRAECKNPVLHPGECCPTCLR 259
+C+ + G Q DC CVHG RP C + C G C +
Sbjct: 766 ACHICSNPNKHGEQCQEDCG---CVHGLCDNRPGSGGVCQQGTCAPG--FSGRFCNESMG 820
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
C G L +H A CV +G +C +D C P S P
Sbjct: 821 DCGPTG-LAQHCHLH-----ARCVSQEGVARCRCLD-GFEGDGFSCTPSNPCSHPDR--- 870
Query: 320 FCPGVDYCNMGHSCDENATCM--NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
C ENA C+ +L T + C C++G+ GDG C +DEC+ + G
Sbjct: 871 -----------GGCSENAECVPGSLGTHH-CTCHKGWSGDGRVCVAIDECEL--DVRG-G 915
Query: 378 CHSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY-TC 435
CH++ C V G C C G+ D + C +D C GCH A C G C
Sbjct: 916 CHTDALCSYVGPGQSRCTCKLGFA-GDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVC 974
Query: 436 RCRDGYEGDGYTC 448
C G+ GDG++C
Sbjct: 975 TCPPGFGGDGFSC 987
Score = 76.6 bits (180), Expect = 3e-13
Identities = 47/144 (32%), Positives = 63/144 (43%), Gaps = 15/144 (10%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C A C N+ C+C+ G++GDG C D CQ+ HG C + C V
Sbjct: 2064 CAPEAVCRAGNS---CECSLGYEGDGRVCTVADLCQDG---HGG-CSEHANCSQVGTMVT 2116
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDGYTCMH 450
C CL Y D ++C + C +G+ GC A C +T + C C GY GDG C+
Sbjct: 2117 CTCLPDY-EGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLE 2175
Query: 451 -----VDECTEGSHTCHHSARCVN 469
VD C CH A C +
Sbjct: 2176 ESEPPVDRCLGQPPPCHSDAMCTD 2199
Score = 73.7 bits (173), Expect = 2e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 11/117 (9%)
Query: 319 KFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
+ C D C GH C E+A C + T TC C ++GDG +C+ + C + H
Sbjct: 2087 RVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDG---HRGG 2143
Query: 378 CHSNTRCVNV-VGGYVCQCLGGYTRKDKFNCVE-----VDECEGNTHGCHADAVCTN 428
C + C++ + C+C GY D C+E VD C G CH+DA+CT+
Sbjct: 2144 CSEHANCLSTGLNTRRCECHAGYVG-DGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2199
Score = 64.1 bits (149), Expect = 1e-09
Identities = 52/175 (29%), Positives = 70/175 (40%), Gaps = 25/175 (14%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C + CM+ ++ C C GF G C+ C A G
Sbjct: 1965 GSECQACPG----GPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTA--CE---LC--APGA 2013
Query: 374 HGHHCHS-----NTRCVNVVGGY-VCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVC 426
G HC + + RC +GG C C G+T C V+++ T C +AVC
Sbjct: 2014 FGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGP---RCEVQLELQPVCTPPCAPEAVC 2070
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTE 481
+C C GYEGDG C D C +G C A C + C C +
Sbjct: 2071 R---AGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPD 2122
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/170 (28%), Positives = 68/170 (40%), Gaps = 16/170 (9%)
Query: 315 GECCKFC-PGV--DYCNMGHSCDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEA 370
G C+ C PG +C C + C L +C C++G+ G C+ E Q
Sbjct: 2003 GTACELCAPGAFGPHCQACR-CTVHGRCDEGLGGSGSCFCDEGWTGP--RCEVQLELQP- 2058
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+ C C G C+C GY + C D C+ GC A C+
Sbjct: 2059 --VCTPPCAPEAVCR---AGNSCECSLGYEGDGRV-CTVADLCQDGHGGCSEHANCSQVG 2112
Query: 431 GSYTCRCRDGYEGDGYTCMHVDECTEGSH-TCHHSARCVNID-GGFRCEC 478
TC C YEGDG++C + CT+G C A C++ RCEC
Sbjct: 2113 TMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCEC 2162
Score = 59.7 bits (138), Expect = 3e-08
Identities = 48/173 (27%), Positives = 68/173 (39%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG +G C + C + C C++GF G T +V E G
Sbjct: 1326 GTLCEPCPG----GLGGVCSGHGQCQDRFLGSGECHCHEGFHG---TACEVCEL----GR 1374
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCT 427
+G +C C + + G C C G+ + +C C +A C
Sbjct: 1375 YGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRK---CDPNANCV 1431
Query: 428 -NTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
++ G+ TC C GY G+G C VD C G C A C + G R C C
Sbjct: 1432 QDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1484
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKY------TCKCNQGFQGDGLTCQDVDECQ 368
G C+ C D G C +C++ + +C C G+ G Q++ CQ
Sbjct: 144 GSACQECQ--DPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCD-QELPVCQ 200
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTN 428
E C NT+C C+CL GYT++ C + C + C A C+
Sbjct: 201 EL------RCPQNTQCSAEAPS--CRCLPGYTQQGS-ECRAPNPCWPSP--CSLLAQCSV 249
Query: 429 TP-GSYTCRCRDGYEGDGYTCMHVDECTEGSHTC-HHSARCV-NIDGGFRCEC 478
+P G C C + Y GDG C+ D CT+ C +S CV G C C
Sbjct: 250 SPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTC 302
Score = 57.6 bits (133), Expect = 1e-07
Identities = 84/343 (24%), Positives = 113/343 (32%), Gaps = 39/343 (11%)
Query: 130 LFKGALQEVRLVSGPHGYLAQCPGLDSE-CPTCGQFALLQATVQELTTHIHDLSLKLVGA 188
LFKG +V+ H C + + CP+ L Q+ + L +V
Sbjct: 28 LFKGC--DVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQ-LGGSMVSM 84
Query: 189 EARISRLEQCDCQKSC---YSNGTVHADGATWQRDCN-RCSCVHG---EITCRPVECDRA 241
+ + QK+C Y H + CN +C+ G TC E R
Sbjct: 85 SGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRG 144
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPEL-AC 300
P P C C + HG P+ C+C G D EL C
Sbjct: 145 SACQECQDPNRFGPDCQSVCSCVHGVCNHG----PRGDGSCLCFAGYTG-PHCDQELPVC 199
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC------------MNLNTKYTC 348
L C Q S C+ PG Y G C C ++ + C
Sbjct: 200 QELRCPQNTQCSAEAPSCRCLPG--YTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQC 257
Query: 349 KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN-TRCVNVVGGYV-CQCLGGYTRKDKFN 406
C + + GDG+ C D C + L G C SN T CV G C C G + N
Sbjct: 258 HCPENYHGDGMVCLPKDPCTD--NLGG--CPSNSTLCVYQKPGQAFCTCRPGLVSINS-N 312
Query: 407 CVEVDECEGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDGYTC 448
+ C A C T G +C CR+ GDG C
Sbjct: 313 ASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRAC 355
Score = 56.4 bits (130), Expect = 3e-07
Identities = 56/199 (28%), Positives = 75/199 (37%), Gaps = 38/199 (19%)
Query: 317 CCK--FCPGVDYCNMGHS--CDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAG 371
CCK F P C G S C C + + C C ++G + C +
Sbjct: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKG--IACHICSNPNK-- 775
Query: 372 GLHGHHCHSNTRCVNVV------GGYVCQ---CLGGYTRKDKFNCVEVDEC--EGNTHGC 420
HG C + CV+ + G VCQ C G++ +F + +C G C
Sbjct: 776 --HGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS--GRFCNESMGDCGPTGLAQHC 831
Query: 421 HADAVCTNTPGSYTCRCRDGYEGDGYTCM------HVD--------ECTEGSHTCHHSAR 466
H A C + G CRC DG+EGDG++C H D EC GS HH
Sbjct: 832 HLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTC 891
Query: 467 CVNIDGGFRCECFTENCEL 485
G R + CEL
Sbjct: 892 HKGWSGDGRVCVAIDECEL 910
>BC078659-1|AAH78659.1| 1821|Homo sapiens latent transforming growth
factor beta binding protein 2 protein.
Length = 1821
Score = 111 bits (267), Expect = 7e-24
Identities = 91/295 (30%), Positives = 117/295 (39%), Gaps = 29/295 (9%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVEC-DRAECKNPVLHP-GEC 253
++C C G T C C G I R C D EC++P P G C
Sbjct: 926 QECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRC 985
Query: 254 CPT-CLRQCLLWGNLY--EHGERFAPKEC-AECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
+ CL Y + G EC VC G +CT ++ C C+ Q
Sbjct: 986 VNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG--KCTNLEGSFRC---SCE--Q 1038
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK-CNQGF--QGDGLTCQDVDE 366
+ V + K C VD C SC C+N + C C G+ DG C+D+DE
Sbjct: 1039 GYEVTSD-EKGCQDVDECASRASC-PTGLCLNTEGSFACSACENGYWVNEDGTACEDLDE 1096
Query: 367 CQEAGGLHGHHCHSNTRCVNVVGGYVCQ-CLGGYTRKD-KFNCVEVDECEGNTHGCHADA 424
C G C S C N G + C+ C GGY +C +VDECE C
Sbjct: 1097 CAFPG-----VCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC-LGG 1149
Query: 425 VCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C NT GSY C C G++ +G C V+EC H H C+N G F C C
Sbjct: 1150 ECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPH-GECLNSHGSFFCLC 1203
Score = 109 bits (262), Expect = 3e-23
Identities = 63/183 (34%), Positives = 88/183 (48%), Gaps = 21/183 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGD 357
R C P Q P + +C + C + C C+N Y+C C G+ G
Sbjct: 869 RCVCSPGYQLH-PSQA--YCTDDNEC-LRDPCKGKGRCINRVGSYSCFCYPGYTLATSGA 924
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
CQD++EC++ G G +C N G Y C+C GY K +C +++EC
Sbjct: 925 TQECQDINECEQPGVCSGG------QCTNTEGSYHCECDQGYIMVRKGHCQDINEC--RH 976
Query: 418 HGCHADAVCTNTPGSYTC-RCRDGYEGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
G D C N+PGSYTC C +GY G +C+ V+EC T G C H +C N++G FR
Sbjct: 977 PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPG--VCAH-GKCTNLEGSFR 1033
Query: 476 CEC 478
C C
Sbjct: 1034 CSC 1036
Score = 96.7 bits (230), Expect = 2e-19
Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 13/167 (7%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHC 378
C VD C C C+N + C C GFQ + C D+DEC++ +G
Sbjct: 1216 CQDVDECATTDPC-VGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECED----YGDPV 1270
Query: 379 HSNTRCVNVVGGYVCQ--CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
+C N G Y C C G+ +C+++DEC +T C + C NT GS+ C
Sbjct: 1271 CGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM-CGSHGFCDNTDGSFRCL 1329
Query: 437 CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTE 481
C G+E G+ C+ V+EC C +A C N++G F C C ++
Sbjct: 1330 CDQGFEISPSGWDCVDVNECELMLAVC-GAALCENVEGSFLCLCASD 1375
Score = 93.9 bits (223), Expect = 2e-18
Identities = 88/289 (30%), Positives = 120/289 (41%), Gaps = 44/289 (15%)
Query: 220 DCNRCSCVHG-EITCRPVEC-DRAEC-KNPVLHPGECCPTC-LRQCLLWGNLYEHGERFA 275
D RC C G ++ C D EC ++P G C C + Y A
Sbjct: 866 DGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPG-YTLATSGA 924
Query: 276 PKECA---EC----VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN 328
+EC EC VC G QCT + C CD G C ++ C
Sbjct: 925 TQECQDINECEQPGVCSGG--QCTNTEGSYHCE---CDQGYIMVRKGHC----QDINECR 975
Query: 329 MGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGL-HGHHCHSNTRCVN 386
+C + C+N YTC C +G++G +C DV+EC G HG +C N
Sbjct: 976 HPGTCPDGR-CVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-------KCTN 1027
Query: 387 VVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-CRDGY--E 442
+ G + C C GY D+ C +VDEC C +C NT GS+ C C +GY
Sbjct: 1028 LEGSFRCSCEQGYEVTSDEKGCQDVDECASRA-SCPT-GLCLNTEGSFACSACENGYWVN 1085
Query: 443 GDGYTCMHVDECT-EG---SHTCHHSA---RCVNIDGGFRCECFTENCE 484
DG C +DEC G S C ++A C + DGG+R ++CE
Sbjct: 1086 EDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE 1134
Score = 93.5 bits (222), Expect = 2e-18
Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 24/210 (11%)
Query: 278 ECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA C G C + AC C+ + G C+ +D C C +
Sbjct: 1054 ECASRASCPTG--LCLNTEGSFACSA--CENGYWVNEDGTACE---DLDECAFPGVCP-S 1105
Query: 337 ATCMNLNTKYTCK-CNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N ++CK C+ G++ L +C+DVDEC++ C C N VG Y C
Sbjct: 1106 GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQS----SCLGG-ECKNTVGSYQC 1160
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EGDGYTCMH 450
C G+ + C +V+EC G H C C N+ GS+ C C G+ EG G +C
Sbjct: 1161 LCPQGFQLANGTVCEDVNECMGEEH-CAPHGECLNSHGSFFCLCAPGFVSAEG-GTSCQD 1218
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFT 480
VDEC + C CVN +G F C C T
Sbjct: 1219 VDECAT-TDPC-VGGHCVNTEGSFNCLCET 1246
Score = 89.8 bits (213), Expect = 3e-17
Identities = 59/164 (35%), Positives = 74/164 (45%), Gaps = 21/164 (12%)
Query: 322 PGVDYCNMGHS--CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
PG+D C G + C TC+NL Y C C+ G+Q C D +EC
Sbjct: 843 PGIDRCAAGATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR------DP 895
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDK---FNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
C RC+N VG Y C C GYT C +++ECE G + CTNT GSY
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECE--QPGVCSGGQCTNTEGSYH 953
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY G+ C ++EC TC RCVN G + C
Sbjct: 954 CECDQGYIMVRKGH-CQDINECRHPG-TC-PDGRCVNSPGSYTC 994
Score = 55.6 bits (128), Expect = 5e-07
Identities = 40/127 (31%), Positives = 53/127 (41%), Gaps = 11/127 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCK--CNQGFQ-GDGLTCQDVDECQEAGGLHGH 376
C +D C + G C N Y C C GF C D+DEC +
Sbjct: 1257 CVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECA-----NDT 1311
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C S+ C N G + C C G+ ++CV+V+ECE C A A+C N GS+ C
Sbjct: 1312 MCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGA-ALCENVEGSFLC 1370
Query: 436 RCRDGYE 442
C E
Sbjct: 1371 LCASDLE 1377
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/75 (37%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRC 384
C + + C EN C+ + YTC C +GFQ D + C DV+EC + G H C
Sbjct: 1737 CGILNGC-ENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG--YC 1793
Query: 385 VNVVGGYVCQCLGGY 399
N G Y C C GY
Sbjct: 1794 ENTEGSYRCHCSPGY 1808
Score = 53.6 bits (123), Expect = 2e-06
Identities = 32/80 (40%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECE---GNTHGCH 421
+ +E G L+G C N RCV V GY C C G+ CV+V+EC+ G C
Sbjct: 1733 QAEECGILNG--CE-NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLC- 1788
Query: 422 ADAVCTNTPGSYTCRCRDGY 441
C NT GSY C C GY
Sbjct: 1789 VHGYCENTEGSYRCHCSPGY 1808
Score = 49.6 bits (113), Expect = 3e-05
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 17/132 (12%)
Query: 269 EHGERFAPKECAEC---VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVD 325
E GE EC + VC G +C C L C P + G+C +D
Sbjct: 1253 ESGECVDIDECEDYGDPVC--GTWKCENSPGSYRCV-LGCQPGFHMAPNGDCID----ID 1305
Query: 326 YCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTR 383
C C + C N + + C C+QGF+ G C DV+EC+ + G
Sbjct: 1306 ECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCG-----AAL 1360
Query: 384 CVNVVGGYVCQC 395
C NV G ++C C
Sbjct: 1361 CENVEGSFLCLC 1372
Score = 48.8 bits (111), Expect = 6e-05
Identities = 39/125 (31%), Positives = 49/125 (39%), Gaps = 18/125 (14%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLH 374
G+ C CP D C + + +T F T D DEC +
Sbjct: 1445 GDACDLCPSEDSAEFSEICPSGKGYIPVEGAWT------FGQTMYT--DADECV----IF 1492
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGG--YTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS 432
G N RC+N V GYVC C G Y K C + DEC+ C + C NT GS
Sbjct: 1493 GPGLCPNGRCLNTVPGYVCLCNPGFHYDASHK-KCEDHDECQ--DLACE-NGECVNTEGS 1548
Query: 433 YTCRC 437
+ C C
Sbjct: 1549 FHCFC 1553
Score = 45.6 bits (103), Expect = 6e-04
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 8/79 (10%)
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCMHVDECTE---GSH 459
F ++ +EC G +GC + C YTC C +G++ D C+ V+EC + +
Sbjct: 1729 FEGLQAEEC-GILNGCE-NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAV 1786
Query: 460 TCHHSARCVNIDGGFRCEC 478
C H C N +G +RC C
Sbjct: 1787 LCVH-GYCENTEGSYRCHC 1804
Score = 45.2 bits (102), Expect = 7e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
+C GY R + +C +++EC T G DA C NT GSY C CR G
Sbjct: 607 ECPQGYKRLNLTHCQDINECL--TLGLCKDAECVNTRGSYLCTCRPG 651
Score = 43.2 bits (97), Expect = 0.003
Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 6/73 (8%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE---GDGYTCMHVDECTEGSHTCHHSAR 466
+D C C N P Y C C GY+ Y C +EC C R
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAY-CTDDNECLR--DPCKGKGR 901
Query: 467 CVNIDGGFRCECF 479
C+N G + C C+
Sbjct: 902 CINRVGSYSCFCY 914
Score = 42.7 bits (96), Expect = 0.004
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 5/72 (6%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEGSHTCHHSAR 466
+ DEC G + C NT Y C C G Y+ C DEC + C +
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD--LAC-ENGE 1541
Query: 467 CVNIDGGFRCEC 478
CVN +G F C C
Sbjct: 1542 CVNTEGSFHCFC 1553
Score = 36.7 bits (81), Expect = 0.26
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 7/51 (13%)
Query: 349 KCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+C QG++ LT CQD++EC G C + CVN G Y+C C G
Sbjct: 607 ECPQGYKRLNLTHCQDINECLTLG-----LC-KDAECVNTRGSYLCTCRPG 651
>AB209865-1|BAD93102.1| 1700|Homo sapiens latent transforming growth
factor beta binding protein 2 variant protein.
Length = 1700
Score = 111 bits (267), Expect = 7e-24
Identities = 91/295 (30%), Positives = 117/295 (39%), Gaps = 29/295 (9%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVEC-DRAECKNPVLHP-GEC 253
++C C G T C C G I R C D EC++P P G C
Sbjct: 805 QECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRC 864
Query: 254 CPT-CLRQCLLWGNLY--EHGERFAPKEC-AECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
+ CL Y + G EC VC G +CT ++ C C+ Q
Sbjct: 865 VNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG--KCTNLEGSFRC---SCE--Q 917
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK-CNQGF--QGDGLTCQDVDE 366
+ V + K C VD C SC C+N + C C G+ DG C+D+DE
Sbjct: 918 GYEVTSD-EKGCQDVDECASRASC-PTGLCLNTEGSFACSACENGYWVNEDGTACEDLDE 975
Query: 367 CQEAGGLHGHHCHSNTRCVNVVGGYVCQ-CLGGYTRKD-KFNCVEVDECEGNTHGCHADA 424
C G C S C N G + C+ C GGY +C +VDECE C
Sbjct: 976 CAFPG-----VCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSC-LGG 1028
Query: 425 VCTNTPGSYTCRCRDGYE-GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C NT GSY C C G++ +G C V+EC H H C+N G F C C
Sbjct: 1029 ECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPH-GECLNSHGSFFCLC 1082
Score = 109 bits (262), Expect = 3e-23
Identities = 63/183 (34%), Positives = 88/183 (48%), Gaps = 21/183 (11%)
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF----QGD 357
R C P Q P + +C + C + C C+N Y+C C G+ G
Sbjct: 748 RCVCSPGYQLH-PSQA--YCTDDNEC-LRDPCKGKGRCINRVGSYSCFCYPGYTLATSGA 803
Query: 358 GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
CQD++EC++ G G +C N G Y C+C GY K +C +++EC
Sbjct: 804 TQECQDINECEQPGVCSGG------QCTNTEGSYHCECDQGYIMVRKGHCQDINEC--RH 855
Query: 418 HGCHADAVCTNTPGSYTC-RCRDGYEGDGYTCMHVDEC-TEGSHTCHHSARCVNIDGGFR 475
G D C N+PGSYTC C +GY G +C+ V+EC T G C H +C N++G FR
Sbjct: 856 PGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPG--VCAH-GKCTNLEGSFR 912
Query: 476 CEC 478
C C
Sbjct: 913 CSC 915
Score = 96.7 bits (230), Expect = 2e-19
Identities = 53/167 (31%), Positives = 78/167 (46%), Gaps = 13/167 (7%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHC 378
C VD C C C+N + C C GFQ + C D+DEC++ +G
Sbjct: 1095 CQDVDECATTDPC-VGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECED----YGDPV 1149
Query: 379 HSNTRCVNVVGGYVCQ--CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
+C N G Y C C G+ +C+++DEC +T C + C NT GS+ C
Sbjct: 1150 CGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTM-CGSHGFCDNTDGSFRCL 1208
Query: 437 CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTE 481
C G+E G+ C+ V+EC C +A C N++G F C C ++
Sbjct: 1209 CDQGFEISPSGWDCVDVNECELMLAVC-GAALCENVEGSFLCLCASD 1254
Score = 93.9 bits (223), Expect = 2e-18
Identities = 88/289 (30%), Positives = 120/289 (41%), Gaps = 44/289 (15%)
Query: 220 DCNRCSCVHG-EITCRPVEC-DRAEC-KNPVLHPGECCPTC-LRQCLLWGNLYEHGERFA 275
D RC C G ++ C D EC ++P G C C + Y A
Sbjct: 745 DGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPG-YTLATSGA 803
Query: 276 PKECA---EC----VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN 328
+EC EC VC G QCT + C CD G C ++ C
Sbjct: 804 TQECQDINECEQPGVCSGG--QCTNTEGSYHCE---CDQGYIMVRKGHC----QDINECR 854
Query: 329 MGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGL-HGHHCHSNTRCVN 386
+C + C+N YTC C +G++G +C DV+EC G HG +C N
Sbjct: 855 HPGTCPDGR-CVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG-------KCTN 906
Query: 387 VVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR-CRDGY--E 442
+ G + C C GY D+ C +VDEC C +C NT GS+ C C +GY
Sbjct: 907 LEGSFRCSCEQGYEVTSDEKGCQDVDECASRA-SCPT-GLCLNTEGSFACSACENGYWVN 964
Query: 443 GDGYTCMHVDECT-EG---SHTCHHSA---RCVNIDGGFRCECFTENCE 484
DG C +DEC G S C ++A C + DGG+R ++CE
Sbjct: 965 EDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE 1013
Score = 93.5 bits (222), Expect = 2e-18
Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 24/210 (11%)
Query: 278 ECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
ECA C G C + AC C+ + G C+ +D C C +
Sbjct: 933 ECASRASCPTG--LCLNTEGSFACSA--CENGYWVNEDGTACE---DLDECAFPGVCP-S 984
Query: 337 ATCMNLNTKYTCK-CNQGFQGDGL--TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
C N ++CK C+ G++ L +C+DVDEC++ C C N VG Y C
Sbjct: 985 GVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQS----SCLGG-ECKNTVGSYQC 1039
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EGDGYTCMH 450
C G+ + C +V+EC G H C C N+ GS+ C C G+ EG G +C
Sbjct: 1040 LCPQGFQLANGTVCEDVNECMGEEH-CAPHGECLNSHGSFFCLCAPGFVSAEG-GTSCQD 1097
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFT 480
VDEC + C CVN +G F C C T
Sbjct: 1098 VDECAT-TDPC-VGGHCVNTEGSFNCLCET 1125
Score = 89.8 bits (213), Expect = 3e-17
Identities = 59/164 (35%), Positives = 74/164 (45%), Gaps = 21/164 (12%)
Query: 322 PGVDYCNMGHS--CDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHH 377
PG+D C G + C TC+NL Y C C+ G+Q C D +EC
Sbjct: 722 PGIDRCAAGATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR------DP 774
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDK---FNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
C RC+N VG Y C C GYT C +++ECE G + CTNT GSY
Sbjct: 775 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECE--QPGVCSGGQCTNTEGSYH 832
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C C GY G+ C ++EC TC RCVN G + C
Sbjct: 833 CECDQGYIMVRKGH-CQDINECRHPG-TC-PDGRCVNSPGSYTC 873
Score = 55.6 bits (128), Expect = 5e-07
Identities = 40/127 (31%), Positives = 53/127 (41%), Gaps = 11/127 (8%)
Query: 321 CPGVDYC-NMGHSCDENATCMNLNTKYTCK--CNQGFQ-GDGLTCQDVDECQEAGGLHGH 376
C +D C + G C N Y C C GF C D+DEC +
Sbjct: 1136 CVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECA-----NDT 1190
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECEGNTHGCHADAVCTNTPGSYTC 435
C S+ C N G + C C G+ ++CV+V+ECE C A A+C N GS+ C
Sbjct: 1191 MCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGA-ALCENVEGSFLC 1249
Query: 436 RCRDGYE 442
C E
Sbjct: 1250 LCASDLE 1256
Score = 54.0 bits (124), Expect = 2e-06
Identities = 28/75 (37%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRC 384
C + + C EN C+ + YTC C +GFQ D + C DV+EC + G H C
Sbjct: 1616 CGILNGC-ENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG--YC 1672
Query: 385 VNVVGGYVCQCLGGY 399
N G Y C C GY
Sbjct: 1673 ENTEGSYRCHCSPGY 1687
Score = 53.6 bits (123), Expect = 2e-06
Identities = 32/80 (40%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 366 ECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK-FNCVEVDECE---GNTHGCH 421
+ +E G L+G C N RCV V GY C C G+ CV+V+EC+ G C
Sbjct: 1612 QAEECGILNG--CE-NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLC- 1667
Query: 422 ADAVCTNTPGSYTCRCRDGY 441
C NT GSY C C GY
Sbjct: 1668 VHGYCENTEGSYRCHCSPGY 1687
Score = 49.6 bits (113), Expect = 3e-05
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 17/132 (12%)
Query: 269 EHGERFAPKECAEC---VCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVD 325
E GE EC + VC G +C C L C P + G+C +D
Sbjct: 1132 ESGECVDIDECEDYGDPVC--GTWKCENSPGSYRCV-LGCQPGFHMAPNGDCID----ID 1184
Query: 326 YCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTR 383
C C + C N + + C C+QGF+ G C DV+EC+ + G
Sbjct: 1185 ECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCG-----AAL 1239
Query: 384 CVNVVGGYVCQC 395
C NV G ++C C
Sbjct: 1240 CENVEGSFLCLC 1251
Score = 48.8 bits (111), Expect = 6e-05
Identities = 39/125 (31%), Positives = 49/125 (39%), Gaps = 18/125 (14%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLH 374
G+ C CP D C + + +T F T D DEC +
Sbjct: 1324 GDACDLCPSEDSAEFSEICPSGKGYIPVEGAWT------FGQTMYT--DADECV----IF 1371
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGG--YTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS 432
G N RC+N V GYVC C G Y K C + DEC+ C + C NT GS
Sbjct: 1372 GPGLCPNGRCLNTVPGYVCLCNPGFHYDASHK-KCEDHDECQ--DLACE-NGECVNTEGS 1427
Query: 433 YTCRC 437
+ C C
Sbjct: 1428 FHCFC 1432
Score = 45.6 bits (103), Expect = 6e-04
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 8/79 (10%)
Query: 405 FNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCMHVDECTE---GSH 459
F ++ +EC G +GC + C YTC C +G++ D C+ V+EC + +
Sbjct: 1608 FEGLQAEEC-GILNGCE-NGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAV 1665
Query: 460 TCHHSARCVNIDGGFRCEC 478
C H C N +G +RC C
Sbjct: 1666 LCVH-GYCENTEGSYRCHC 1683
Score = 45.2 bits (102), Expect = 7e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 394 QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG 440
+C GY R + +C +++EC T G DA C NT GSY C CR G
Sbjct: 486 ECPQGYKRLNLTHCQDINECL--TLGLCKDAECVNTRGSYLCTCRPG 530
Score = 43.2 bits (97), Expect = 0.003
Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 6/73 (8%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE---GDGYTCMHVDECTEGSHTCHHSAR 466
+D C C N P Y C C GY+ Y C +EC C R
Sbjct: 724 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAY-CTDDNECLR--DPCKGKGR 780
Query: 467 CVNIDGGFRCECF 479
C+N G + C C+
Sbjct: 781 CINRVGSYSCFCY 793
Score = 42.7 bits (96), Expect = 0.004
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 5/72 (6%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEGSHTCHHSAR 466
+ DEC G + C NT Y C C G Y+ C DEC + C +
Sbjct: 1364 DADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD--LAC-ENGE 1420
Query: 467 CVNIDGGFRCEC 478
CVN +G F C C
Sbjct: 1421 CVNTEGSFHCFC 1432
Score = 36.7 bits (81), Expect = 0.26
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 7/51 (13%)
Query: 349 KCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+C QG++ LT CQD++EC G C + CVN G Y+C C G
Sbjct: 486 ECPQGYKRLNLTHCQDINECLTLG-----LC-KDAECVNTRGSYLCTCRPG 530
>AB052956-1|BAC15606.1| 2570|Homo sapiens FELE-1 protein.
Length = 2570
Score = 111 bits (267), Expect = 7e-24
Identities = 75/226 (33%), Positives = 102/226 (45%), Gaps = 24/226 (10%)
Query: 261 CLLWGNLYEHGERFAPKECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
C + N +HGE +C E C C G R C + C P FS G C
Sbjct: 767 CHICSNPNKHGE-----QCQEDCGCVHGLCD-NRPGSGGVCQQGTCAPG--FS--GRFCN 816
Query: 320 FCPG-VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQ--EAGGLHGH 376
G + C +A C++ C+C GF+GDG +C + C + GG
Sbjct: 817 ESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGG---- 872
Query: 377 HCHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG-CHADAVCTNT-PGSY 433
C N CV +G + C C G++ + CV +DECE + G CH DA+C+ PG
Sbjct: 873 -CSENAECVPGSLGTHHCTCHKGWSGDGRV-CVAIDECELDVRGGCHTDALCSYVGPGQS 930
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
C C+ G+ GDGY C +D C G+ CH A C + GG R C C
Sbjct: 931 RCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTC 976
Score = 99 bits (238), Expect = 2e-20
Identities = 56/154 (36%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 333 CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH-CHSNTRCVNVVGG 390
CD NA C+ + TC C G+ G+G+ C +VD C HGH C + C V G
Sbjct: 1424 CDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCA-----HGHGGCSPHANCTKVAPG 1478
Query: 391 Y-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGY-T 447
C C GY + C E++ C + GCH A C T P +C CR+GY GDG T
Sbjct: 1479 QRTCTCQDGYMGDGEL-CQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1537
Query: 448 CMHVDECTEGSHTCHHSARCVNI-DGGFRCECFT 480
C +D C++ + C A C + DG C C T
Sbjct: 1538 CELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDT 1571
Score = 91.1 bits (216), Expect = 1e-17
Identities = 62/187 (33%), Positives = 80/187 (42%), Gaps = 25/187 (13%)
Query: 282 CVCHDGNMQCTRVDPELACPRLP--CDPPQ---QFSVPGECCK----------FCPGVDY 326
CVC+ G Q R D ++ P+ P CDP Q S C FC VD
Sbjct: 1400 CVCNVG-WQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDP 1458
Query: 327 CNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C GH C +A C + + TC C G+ GDG CQ+++ C +H CH + C
Sbjct: 1459 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCL----IHHGGCHIHAEC 1514
Query: 385 VNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYE 442
+ V C C GY+ C +D C N GC A C +T G TC C +
Sbjct: 1515 IPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHT 1574
Query: 443 -GDGYTC 448
GDG TC
Sbjct: 1575 VGDGLTC 1581
Score = 83.8 bits (198), Expect = 2e-15
Identities = 53/151 (35%), Positives = 63/151 (41%), Gaps = 17/151 (11%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C GV C+ H C E L +C CN G+QG L C + C
Sbjct: 1379 CTGV--CDCAHGLCQEG-----LQGDGSCVCNVGWQG--LRCDQKITSPQCP----RKCD 1425
Query: 380 SNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRC 437
N CV + G C C GY+ F C EVD C GC A CT PG TC C
Sbjct: 1426 PNANCVQDSAGASTCACAAGYSGNGIF-CSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1484
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCV 468
+DGY GDG C ++ C CH A C+
Sbjct: 1485 QDGYMGDGELCQEINSCLIHHGGCHIHAECI 1515
Score = 82.2 bits (194), Expect = 5e-15
Identities = 72/253 (28%), Positives = 98/253 (38%), Gaps = 38/253 (15%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVE---CDRAECKNPVLHPGECCPTCLR 259
+C+ + G Q DC CVHG RP C + C G C +
Sbjct: 766 ACHICSNPNKHGEQCQEDCG---CVHGLCDNRPGSGGVCQQGTCAPG--FSGRFCNESMG 820
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
C G L +H A CV +G +C +D C P S P
Sbjct: 821 DCGPTG-LAQHCHLH-----ARCVSQEGVARCRCLD-GFEGDGFSCTPSNPCSHPDR--- 870
Query: 320 FCPGVDYCNMGHSCDENATCM--NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
C ENA C+ +L T + C C++G+ GDG C +DEC+ + G
Sbjct: 871 -----------GGCSENAECVPGSLGTHH-CTCHKGWSGDGRVCVAIDECEL--DVRG-G 915
Query: 378 CHSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY-TC 435
CH++ C V G C C G+ D + C +D C GCH A C G C
Sbjct: 916 CHTDALCSYVGPGQSRCTCKLGFA-GDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVC 974
Query: 436 RCRDGYEGDGYTC 448
C G+ GDG++C
Sbjct: 975 TCPPGFGGDGFSC 987
Score = 77.4 bits (182), Expect = 1e-13
Identities = 47/145 (32%), Positives = 64/145 (44%), Gaps = 15/145 (10%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C A C N+ C+C+ G++GDG C D CQ+ HG C + C V
Sbjct: 2064 CAPEAVCRAGNS---CECSLGYEGDGRVCTVADLCQDG---HGG-CSEHANCSQVGTMVT 2116
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDGYTCMH 450
C CL Y D ++C + C +G+ GC A C +T + C C GY GDG C+
Sbjct: 2117 CTCLPDY-EGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLE 2175
Query: 451 -----VDECTEGSHTCHHSARCVNI 470
VD C CH A C ++
Sbjct: 2176 ESEPPVDRCLGQPPPCHSDAMCTDL 2200
Score = 73.7 bits (173), Expect = 2e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 11/117 (9%)
Query: 319 KFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
+ C D C GH C E+A C + T TC C ++GDG +C+ + C + H
Sbjct: 2087 RVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDG---HRGG 2143
Query: 378 CHSNTRCVNV-VGGYVCQCLGGYTRKDKFNCVE-----VDECEGNTHGCHADAVCTN 428
C + C++ + C+C GY D C+E VD C G CH+DA+CT+
Sbjct: 2144 CSEHANCLSTGLNTRRCECHAGYVG-DGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2199
Score = 64.1 bits (149), Expect = 1e-09
Identities = 52/175 (29%), Positives = 70/175 (40%), Gaps = 25/175 (14%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C + CM+ ++ C C GF G C+ C A G
Sbjct: 1965 GSECQACPG----GPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTA--CE---LC--APGA 2013
Query: 374 HGHHCHS-----NTRCVNVVGGY-VCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVC 426
G HC + + RC +GG C C G+T C V+++ T C +AVC
Sbjct: 2014 FGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGP---RCEVQLELQPVCTPPCAPEAVC 2070
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTE 481
+C C GYEGDG C D C +G C A C + C C +
Sbjct: 2071 R---AGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPD 2122
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/170 (28%), Positives = 68/170 (40%), Gaps = 16/170 (9%)
Query: 315 GECCKFC-PGV--DYCNMGHSCDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEA 370
G C+ C PG +C C + C L +C C++G+ G C+ E Q
Sbjct: 2003 GTACELCAPGAFGPHCQACR-CTVHGRCDEGLGGSGSCFCDEGWTGP--RCEVQLELQP- 2058
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+ C C G C+C GY + C D C+ GC A C+
Sbjct: 2059 --VCTPPCAPEAVCR---AGNSCECSLGYEGDGRV-CTVADLCQDGHGGCSEHANCSQVG 2112
Query: 431 GSYTCRCRDGYEGDGYTCMHVDECTEGSH-TCHHSARCVNID-GGFRCEC 478
TC C YEGDG++C + CT+G C A C++ RCEC
Sbjct: 2113 TMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCEC 2162
Score = 59.7 bits (138), Expect = 3e-08
Identities = 48/173 (27%), Positives = 68/173 (39%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG +G C + C + C C++GF G T +V E G
Sbjct: 1326 GTLCEPCPG----GLGGVCSGHGQCQDRFLGSGECHCHEGFHG---TACEVCEL----GR 1374
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCT 427
+G +C C + + G C C G+ + +C C +A C
Sbjct: 1375 YGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRK---CDPNANCV 1431
Query: 428 -NTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
++ G+ TC C GY G+G C VD C G C A C + G R C C
Sbjct: 1432 QDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1484
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKY------TCKCNQGFQGDGLTCQDVDECQ 368
G C+ C D G C +C++ + +C C G+ G Q++ CQ
Sbjct: 144 GSACQECQ--DPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCD-QELPVCQ 200
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTN 428
E C NT+C C+CL GYT++ C + C + C A C+
Sbjct: 201 EL------RCPQNTQCSAEAPS--CRCLPGYTQQGS-ECRAPNPCWPSP--CSLLAQCSV 249
Query: 429 TP-GSYTCRCRDGYEGDGYTCMHVDECTEGSHTC-HHSARCV-NIDGGFRCEC 478
+P G C C + Y GDG C+ D CT+ C +S CV G C C
Sbjct: 250 SPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTC 302
Score = 57.6 bits (133), Expect = 1e-07
Identities = 84/343 (24%), Positives = 113/343 (32%), Gaps = 39/343 (11%)
Query: 130 LFKGALQEVRLVSGPHGYLAQCPGLDSE-CPTCGQFALLQATVQELTTHIHDLSLKLVGA 188
LFKG +V+ H C + + CP+ L Q+ + L +V
Sbjct: 28 LFKGC--DVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQ-LGGSMVSM 84
Query: 189 EARISRLEQCDCQKSC---YSNGTVHADGATWQRDCN-RCSCVHG---EITCRPVECDRA 241
+ + QK+C Y H + CN +C+ G TC E R
Sbjct: 85 SGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRG 144
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPEL-AC 300
P P C C + HG P+ C+C G D EL C
Sbjct: 145 SACQECQDPNRFGPDCQSVCSCVHGVCNHG----PRGDGSCLCFAGYTG-PHCDQELPVC 199
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC------------MNLNTKYTC 348
L C Q S C+ PG Y G C C ++ + C
Sbjct: 200 QELRCPQNTQCSAEAPSCRCLPG--YTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQC 257
Query: 349 KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN-TRCVNVVGGYV-CQCLGGYTRKDKFN 406
C + + GDG+ C D C + L G C SN T CV G C C G + N
Sbjct: 258 HCPENYHGDGMVCLPKDPCTD--NLGG--CPSNSTLCVYQKPGQAFCTCRPGLVSINS-N 312
Query: 407 CVEVDECEGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDGYTC 448
+ C A C T G +C CR+ GDG C
Sbjct: 313 ASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRAC 355
Score = 56.4 bits (130), Expect = 3e-07
Identities = 56/199 (28%), Positives = 75/199 (37%), Gaps = 38/199 (19%)
Query: 317 CCK--FCPGVDYCNMGHS--CDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAG 371
CCK F P C G S C C + + C C ++G + C +
Sbjct: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKG--IACHICSNPNK-- 775
Query: 372 GLHGHHCHSNTRCVNVV------GGYVCQ---CLGGYTRKDKFNCVEVDEC--EGNTHGC 420
HG C + CV+ + G VCQ C G++ +F + +C G C
Sbjct: 776 --HGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS--GRFCNESMGDCGPTGLAQHC 831
Query: 421 HADAVCTNTPGSYTCRCRDGYEGDGYTCM------HVD--------ECTEGSHTCHHSAR 466
H A C + G CRC DG+EGDG++C H D EC GS HH
Sbjct: 832 HLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTC 891
Query: 467 CVNIDGGFRCECFTENCEL 485
G R + CEL
Sbjct: 892 HKGWSGDGRVCVAIDECEL 910
>AK131562-1|BAD18695.1| 867|Homo sapiens protein ( Homo sapiens
cDNA FLJ16811 fis, clone THYMU3024602, highly similar
to Cell surface glycoprotein EMR1 precursor. ).
Length = 867
Score = 111 bits (266), Expect = 1e-23
Identities = 61/185 (32%), Positives = 82/185 (44%), Gaps = 28/185 (15%)
Query: 311 FSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEA 370
F PG CK ++ C C E++ C+N Y+C C GF TC+DVDEC +
Sbjct: 71 FKDPGVRCK---DINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADP 127
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD--------KFNCVEVDECEGNTHGCHA 422
C + C N VG Y C C G+ K +C ++DEC T C
Sbjct: 128 -----RACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDEC---TEMCPI 179
Query: 423 DAVCTNTPGSYTCRCRDG---------YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGG 473
++ CTNTPGSY C C G + G C +DEC + TC ++ C N G
Sbjct: 180 NSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGS 239
Query: 474 FRCEC 478
+ C C
Sbjct: 240 YSCGC 244
Score = 97.5 bits (232), Expect = 1e-19
Identities = 56/170 (32%), Positives = 78/170 (45%), Gaps = 28/170 (16%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQG---------FQGDGLTCQDVDECQEAGGLHGHH 377
C C ATC N Y C C QG F+ G+ C+D++EC L
Sbjct: 35 CRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDINEC-----LTSSV 89
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C ++ CVN +G Y C C G+ ++ C +VDEC + C A C NT G+Y+C C
Sbjct: 90 CPEHSDCVNSMGSYSCSCQVGFISRNS-TCEDVDEC-ADPRACPEHATCNNTVGNYSCFC 147
Query: 438 RDGYE-GDGY--------TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+E G+ +C +DECTE C ++ C N G + C C
Sbjct: 148 NPGFESSSGHLSFQGLKASCEDIDECTE---MCPINSTCTNTPGSYFCTC 194
Score = 87.4 bits (207), Expect = 1e-16
Identities = 48/138 (34%), Positives = 66/138 (47%), Gaps = 24/138 (17%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF---------QGDGLTCQDVDECQEAG 371
C VD C +C E+ATC N Y+C CN GF QG +C+D+DEC E
Sbjct: 118 CEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEM- 176
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKD-KFN-------CVEVDECEGNTHGCHAD 423
C N+ C N G Y C C G+ + + N C ++DEC + C +
Sbjct: 177 ------CPINSTCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPN 230
Query: 424 AVCTNTPGSYTCRCRDGY 441
++CTN GSY+C C G+
Sbjct: 231 SICTNALGSYSCGCIAGF 248
Score = 48.8 bits (111), Expect = 6e-05
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 398 GYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDG---------YEGDGYTC 448
G+ R + + + C +T C A A CTNT SY C C+ G ++ G C
Sbjct: 20 GHIRPTRKPNTKGNNCRDSTL-CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRC 78
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++EC S C + CVN G + C C
Sbjct: 79 KDINECLTSS-VCPEHSDCVNSMGSYSCSC 107
>AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA
sequence from clone GS1-174L6 on chromosome 1. ).
Length = 240
Score = 110 bits (265), Expect = 1e-23
Identities = 52/137 (37%), Positives = 72/137 (52%), Gaps = 13/137 (9%)
Query: 346 YTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC--QCLGGYTRKD 403
+ C C G+Q G C DV+EC++ + C + C N GGY C C G T+ +
Sbjct: 5 FHCGCEPGYQLKGRKCMDVNECRQ------NVCRPDQHCKNTRGGYKCIDLCPNGMTKAE 58
Query: 404 KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTC 461
C+++DEC+ TH C + +C NT GSY C C GY +G G CM +DEC E + C
Sbjct: 59 NGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDEC-ENTDAC 117
Query: 462 HHSARCVNIDGGFRCEC 478
H C N G ++C C
Sbjct: 118 QH--ECKNTFGSYQCIC 132
Score = 100 bits (240), Expect = 1e-20
Identities = 57/162 (35%), Positives = 78/162 (48%), Gaps = 14/162 (8%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTC--KCNQGF-QGDGLTCQDVDECQEAGGLHGHH 377
C V+ C + C + C N Y C C G + + TC D+DEC++ H
Sbjct: 20 CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGT----HQ 74
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C N C N G Y C C GY + C+++DECE NT C + C NT GSY C
Sbjct: 75 CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDIDECE-NTDACQHE--CKNTFGSYQCI 131
Query: 437 CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
C GY+ +G TC +DEC E + C + C N+ G ++C
Sbjct: 132 CPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQC 173
Score = 45.2 bits (102), Expect = 7e-04
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 431 GSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GS+ C C GY+ G CM V+EC + + C C N GG++C
Sbjct: 3 GSFHCGCEPGYQLKGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKC 46
>AJ275213-1|CAB61827.1| 2570|Homo sapiens stabilin-1 protein.
Length = 2570
Score = 110 bits (265), Expect = 1e-23
Identities = 75/226 (33%), Positives = 102/226 (45%), Gaps = 24/226 (10%)
Query: 261 CLLWGNLYEHGERFAPKECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
C + N +HGE +C E C C G R C + C P FS G C
Sbjct: 767 CHICSNPNKHGE-----QCQEDCGCVHGLCD-NRPGSGGVCQQGTCAPG--FS--GRFCN 816
Query: 320 FCPG-VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQ--EAGGLHGH 376
G + C +A C++ C+C GF+GDG +C + C + GG
Sbjct: 817 ESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGG---- 872
Query: 377 HCHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG-CHADAVCTNT-PGSY 433
C N CV +G + C C G++ + CV +DECE + G CH DA+C+ PG
Sbjct: 873 -CSENAECVPGSLGTHHCTCHKGWSGDGRV-CVAIDECELDVGGGCHTDALCSYVGPGQS 930
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
C C+ G+ GDGY C +D C G+ CH A C + GG R C C
Sbjct: 931 RCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTC 976
Score = 99 bits (238), Expect = 2e-20
Identities = 56/154 (36%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 333 CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH-CHSNTRCVNVVGG 390
CD NA C+ + TC C G+ G+G+ C +VD C HGH C + C V G
Sbjct: 1424 CDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDPCA-----HGHGGCSPHANCTKVAPG 1478
Query: 391 Y-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGY-T 447
C C GY + C E++ C + GCH A C T P +C CR+GY GDG T
Sbjct: 1479 QRTCTCQDGYMGDGEL-CQEINSCLIHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRT 1537
Query: 448 CMHVDECTEGSHTCHHSARCVNI-DGGFRCECFT 480
C +D C++ + C A C + DG C C T
Sbjct: 1538 CELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDT 1571
Score = 91.1 bits (216), Expect = 1e-17
Identities = 62/187 (33%), Positives = 80/187 (42%), Gaps = 25/187 (13%)
Query: 282 CVCHDGNMQCTRVDPELACPRLP--CDPPQ---QFSVPGECCK----------FCPGVDY 326
CVC+ G Q R D ++ P+ P CDP Q S C FC VD
Sbjct: 1400 CVCNVG-WQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCSEVDP 1458
Query: 327 CNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
C GH C +A C + + TC C G+ GDG CQ+++ C +H CH + C
Sbjct: 1459 CAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCL----IHHGGCHIHAEC 1514
Query: 385 VNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYE 442
+ V C C GY+ C +D C N GC A C +T G TC C +
Sbjct: 1515 IPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGDGQRTCTCDTAHT 1574
Query: 443 -GDGYTC 448
GDG TC
Sbjct: 1575 VGDGLTC 1581
Score = 85.0 bits (201), Expect = 7e-16
Identities = 73/254 (28%), Positives = 99/254 (38%), Gaps = 40/254 (15%)
Query: 203 SCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVE---CDRAECKNPVLHPGECCPTCLR 259
+C+ + G Q DC CVHG RP C + C G C +
Sbjct: 766 ACHICSNPNKHGEQCQEDCG---CVHGLCDNRPGSGGVCQQGTCAPG--FSGRFCNESMG 820
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
C G L +H A CV +G +C +D C P S P
Sbjct: 821 DCGPTG-LAQHCHLH-----ARCVSQEGVARCRCLD-GFEGDGFSCTPSNPCSHPDR--- 870
Query: 320 FCPGVDYCNMGHSCDENATCM--NLNTKYTCKCNQGFQGDGLTCQDVDECQ-EAGGLHGH 376
C ENA C+ +L T + C C++G+ GDG C +DEC+ + GG
Sbjct: 871 -----------GGCSENAECVPGSLGTHH-CTCHKGWSGDGRVCVAIDECELDVGG---- 914
Query: 377 HCHSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY-T 434
CH++ C V G C C G+ D + C +D C GCH A C G
Sbjct: 915 GCHTDALCSYVGPGQSRCTCKLGFA-GDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQRV 973
Query: 435 CRCRDGYEGDGYTC 448
C C G+ GDG++C
Sbjct: 974 CTCPPGFGGDGFSC 987
Score = 83.8 bits (198), Expect = 2e-15
Identities = 53/151 (35%), Positives = 63/151 (41%), Gaps = 17/151 (11%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C GV C+ H C E L +C CN G+QG L C + C
Sbjct: 1379 CTGV--CDCAHGLCQEG-----LQGDGSCVCNVGWQG--LRCDQKITSPQCP----RKCD 1425
Query: 380 SNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRC 437
N CV + G C C GY+ F C EVD C GC A CT PG TC C
Sbjct: 1426 PNANCVQDSAGASTCACAAGYSGNGIF-CSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1484
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCV 468
+DGY GDG C ++ C CH A C+
Sbjct: 1485 QDGYMGDGELCQEINSCLIHHGGCHIHAECI 1515
Score = 76.6 bits (180), Expect = 3e-13
Identities = 47/144 (32%), Positives = 63/144 (43%), Gaps = 15/144 (10%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C A C N+ C+C+ G++GDG C D CQ+ HG C + C V
Sbjct: 2064 CAPEAVCRAGNS---CECSLGYEGDGRVCTVADLCQDG---HGG-CSEHANCSQVGTMVT 2116
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDGYTCMH 450
C CL Y D ++C + C +G+ GC A C +T + C C GY GDG C+
Sbjct: 2117 CTCLPDY-EGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLE 2175
Query: 451 -----VDECTEGSHTCHHSARCVN 469
VD C CH A C +
Sbjct: 2176 ESEPPVDRCLGQPPPCHSDAMCTD 2199
Score = 73.7 bits (173), Expect = 2e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 11/117 (9%)
Query: 319 KFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH 377
+ C D C GH C E+A C + T TC C ++GDG +C+ + C + H
Sbjct: 2087 RVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDG---HRGG 2143
Query: 378 CHSNTRCVNV-VGGYVCQCLGGYTRKDKFNCVE-----VDECEGNTHGCHADAVCTN 428
C + C++ + C+C GY D C+E VD C G CH+DA+CT+
Sbjct: 2144 CSEHANCLSTGLNTRRCECHAGYVG-DGLQCLEESEPPVDRCLGQPPPCHSDAMCTD 2199
Score = 64.1 bits (149), Expect = 1e-09
Identities = 52/175 (29%), Positives = 70/175 (40%), Gaps = 25/175 (14%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C + CM+ ++ C C GF G C+ C A G
Sbjct: 1965 GSECQACPG----GPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTA--CE---LC--APGA 2013
Query: 374 HGHHCHS-----NTRCVNVVGGY-VCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVC 426
G HC + + RC +GG C C G+T C V+++ T C +AVC
Sbjct: 2014 FGPHCQACRCTVHGRCDEGLGGSGSCFCDEGWTGP---RCEVQLELQPVCTPPCAPEAVC 2070
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTE 481
+C C GYEGDG C D C +G C A C + C C +
Sbjct: 2071 R---AGNSCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPD 2122
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/170 (28%), Positives = 68/170 (40%), Gaps = 16/170 (9%)
Query: 315 GECCKFC-PGV--DYCNMGHSCDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEA 370
G C+ C PG +C C + C L +C C++G+ G C+ E Q
Sbjct: 2003 GTACELCAPGAFGPHCQACR-CTVHGRCDEGLGGSGSCFCDEGWTGP--RCEVQLELQP- 2058
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
+ C C G C+C GY + C D C+ GC A C+
Sbjct: 2059 --VCTPPCAPEAVCR---AGNSCECSLGYEGDGRV-CTVADLCQDGHGGCSEHANCSQVG 2112
Query: 431 GSYTCRCRDGYEGDGYTCMHVDECTEGSH-TCHHSARCVNID-GGFRCEC 478
TC C YEGDG++C + CT+G C A C++ RCEC
Sbjct: 2113 TMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCEC 2162
Score = 59.7 bits (138), Expect = 3e-08
Identities = 48/173 (27%), Positives = 68/173 (39%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG +G C + C + C C++GF G T +V E G
Sbjct: 1326 GTLCEPCPG----GLGGVCSGHGQCQDRFLGSGECHCHEGFHG---TACEVCEL----GR 1374
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCT 427
+G +C C + + G C C G+ + +C C +A C
Sbjct: 1375 YGPNCTGVCDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRK---CDPNANCV 1431
Query: 428 -NTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
++ G+ TC C GY G+G C VD C G C A C + G R C C
Sbjct: 1432 QDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTC 1484
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKY------TCKCNQGFQGDGLTCQDVDECQ 368
G C+ C D G C +C++ + +C C G+ G Q++ CQ
Sbjct: 144 GSACQECQ--DPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCD-QELPVCQ 200
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTN 428
E C NT+C C+CL GYT++ C + C + C A C+
Sbjct: 201 EL------RCPQNTQCSAEAPS--CRCLPGYTQQGS-ECRAPNPCWPSP--CSLLAQCSV 249
Query: 429 TP-GSYTCRCRDGYEGDGYTCMHVDECTEGSHTC-HHSARCV-NIDGGFRCEC 478
+P G C C + Y GDG C+ D CT+ C +S CV G C C
Sbjct: 250 SPKGQAQCHCPENYHGDGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTC 302
Score = 57.6 bits (133), Expect = 1e-07
Identities = 84/343 (24%), Positives = 113/343 (32%), Gaps = 39/343 (11%)
Query: 130 LFKGALQEVRLVSGPHGYLAQCPGLDSE-CPTCGQFALLQATVQELTTHIHDLSLKLVGA 188
LFKG +V+ H C + + CP+ L Q+ + L +V
Sbjct: 28 LFKGC--DVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQITQDCRYEVQ-LGGSMVSM 84
Query: 189 EARISRLEQCDCQKSC---YSNGTVHADGATWQRDCN-RCSCVHG---EITCRPVECDRA 241
+ + QK+C Y H + CN +C+ G TC E R
Sbjct: 85 SGCRRKCRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRG 144
Query: 242 ECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPEL-AC 300
P P C C + HG P+ C+C G D EL C
Sbjct: 145 SACQECQDPNRFGPDCQSVCSCVHGVCNHG----PRGDGSCLCFAGYTG-PHCDQELPVC 199
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC------------MNLNTKYTC 348
L C Q S C+ PG Y G C C ++ + C
Sbjct: 200 QELRCPQNTQCSAEAPSCRCLPG--YTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQC 257
Query: 349 KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN-TRCVNVVGGYV-CQCLGGYTRKDKFN 406
C + + GDG+ C D C + L G C SN T CV G C C G + N
Sbjct: 258 HCPENYHGDGMVCLPKDPCTD--NLGG--CPSNSTLCVYQKPGQAFCTCRPGLVSINS-N 312
Query: 407 CVEVDECEGNTHGCHADAVCTNTP-GSYTCRCRDGYEGDGYTC 448
+ C A C T G +C CR+ GDG C
Sbjct: 313 ASAGCFAFCSPFSCDRSATCQVTADGKTSCVCRESEVGDGRAC 355
Score = 56.4 bits (130), Expect = 3e-07
Identities = 56/199 (28%), Positives = 75/199 (37%), Gaps = 38/199 (19%)
Query: 317 CCK--FCPGVDYCNMGHS--CDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAG 371
CCK F P C G S C C + + C C ++G + C +
Sbjct: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKG--IACHICSNPNK-- 775
Query: 372 GLHGHHCHSNTRCVNVV------GGYVCQ---CLGGYTRKDKFNCVEVDEC--EGNTHGC 420
HG C + CV+ + G VCQ C G++ +F + +C G C
Sbjct: 776 --HGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFS--GRFCNESMGDCGPTGLAQHC 831
Query: 421 HADAVCTNTPGSYTCRCRDGYEGDGYTCM------HVD--------ECTEGSHTCHHSAR 466
H A C + G CRC DG+EGDG++C H D EC GS HH
Sbjct: 832 HLHARCVSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTC 891
Query: 467 CVNIDGGFRCECFTENCEL 485
G R + CEL
Sbjct: 892 HKGWSGDGRVCVAIDECEL 910
>AC005327-1|AAC27673.1| 287|Homo sapiens CD97_HUMAN, partial CDS
protein.
Length = 287
Score = 110 bits (265), Expect = 1e-23
Identities = 64/165 (38%), Positives = 79/165 (47%), Gaps = 30/165 (18%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 70 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 125
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
CVN +G Y CQCL G+ KD V+EC + CH+ C N GSY CRCR G+
Sbjct: 126 GTCVNTLGSYTCQCLPGF--KD------VNECTSGQNPCHSSTHCLNNVGSYQCRCRPGW 177
Query: 442 E-------GDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ G T C VDEC+ G H C S C N G + C C
Sbjct: 178 QPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 222
Score = 97.5 bits (232), Expect = 1e-19
Identities = 51/157 (32%), Positives = 76/157 (48%), Gaps = 24/157 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C ++++C+N C+CN GF + +T D++EC + C + C N G
Sbjct: 30 CPQDSSCVNATA---CRCNPGFSSFSEIITTPDINECATLSKVS---CGKFSDCWNTEGS 83
Query: 391 YVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
Y C C GY + + C +VDEC+ N C + C NT GSYTC+C G+
Sbjct: 84 YDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGF 143
Query: 442 EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ V+ECT G + CH S C+N G ++C C
Sbjct: 144 K-------DVNECTSGQNPCHSSTHCLNNVGSYQCRC 173
Score = 93.5 bits (222), Expect = 2e-18
Identities = 49/130 (37%), Positives = 64/130 (49%), Gaps = 19/130 (14%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH 379
C VD C C TC+N YTC+C GF+ DV+EC + CH
Sbjct: 109 CQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFK-------DVNECTSGQ----NPCH 157
Query: 380 SNTRCVNVVGGYVCQCLGGY-------TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS 432
S+T C+N VG Y C+C G+ + C +VDEC H C + VC NT GS
Sbjct: 158 SSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGS 217
Query: 433 YTCRCRDGYE 442
Y+CRCR G++
Sbjct: 218 YSCRCRPGWK 227
>AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens
cDNA FLJ14869 fis, clone PLACE1002474, moderately
similar to Mus musculus matrilin-2 precursor mRNA. ).
Length = 537
Score = 110 bits (264), Expect = 2e-23
Identities = 58/164 (35%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Query: 321 CPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHH 377
C VDYC + H C+ + C+N++ + C+C +G + DG TC +D C L H
Sbjct: 63 CSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTCAKLDSC----ALGDHG 116
Query: 378 CHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
C + CV+ +VCQC GY R+D C D C+ HGC + +C N+ SYTC
Sbjct: 117 CEHS--CVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGC--EHICVNSDDSYTCE 172
Query: 437 CRDGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +G+ DG C D C H C H CVN + C+C
Sbjct: 173 CLEGFRLAEDGKRCRRKDVCKSTHHGCEHI--CVNNGNSYICKC 214
Score = 109 bits (261), Expect = 4e-23
Identities = 59/166 (35%), Positives = 81/166 (48%), Gaps = 18/166 (10%)
Query: 319 KFCPGVDYC-NMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHG 375
K C VD+C H C++ C+N + C+C++GF D +TC VD C L
Sbjct: 20 KTCSRVDHCAQQDHGCEQ--LCLNTEDSFVCQCSEGFLINEDLMTCSRVDYCL----LSD 73
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
H C + CVN+ + CQC G+ R D C ++D C HGC + C ++ S+
Sbjct: 74 HGCEYS--CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGC--EHSCVSSEDSFV 129
Query: 435 CRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+C +GY DG TC D C H C H CVN D + CEC
Sbjct: 130 CQCFEGYILREDGKTCRRKDVCQAIDHGCEHI--CVNSDDSYTCEC 173
Score = 99 bits (238), Expect = 2e-20
Identities = 51/143 (35%), Positives = 70/143 (48%), Gaps = 15/143 (10%)
Query: 342 LNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY 399
+ Y C+C++G+ D G TC VD C + H C C+N +VCQC G+
Sbjct: 1 MEESYYCRCHRGYTLDPNGKTCSRVDHCAQ----QDHGCEQ--LCLNTEDSFVCQCSEGF 54
Query: 400 T-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTE 456
+D C VD C + HGC C N S+ C+C +G+ DG TC +D C
Sbjct: 55 LINEDLMTCSRVDYCLLSDHGCEYS--CVNMDRSFACQCPEGHVLRSDGKTCAKLDSCAL 112
Query: 457 GSHTCHHSARCVNIDGGFRCECF 479
G H C HS CV+ + F C+CF
Sbjct: 113 GDHGCEHS--CVSSEDSFVCQCF 133
Score = 86.2 bits (204), Expect = 3e-16
Identities = 56/179 (31%), Positives = 79/179 (44%), Gaps = 25/179 (13%)
Query: 285 HDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG-HSCDENATCMNLN 343
H C +D AC C G K C +D C +G H C+ + C++
Sbjct: 74 HGCEYSCVNMDRSFACQ---CPEGHVLRSDG---KTCAKLDSCALGDHGCEHS--CVSSE 125
Query: 344 TKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT- 400
+ C+C +G+ + DG TC+ D CQ H C CVN Y C+CL G+
Sbjct: 126 DSFVCQCFEGYILREDGKTCRRKDVCQAID----HGCEHI--CVNSDDSYTCECLEGFRL 179
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
+D C D C+ HGC + +C N SY C+C +G+ DG C +CTEG
Sbjct: 180 AEDGKRCRRKDVCKSTHHGC--EHICVNNGNSYICKCSEGFVLAEDGRRC---KKCTEG 233
Score = 38.3 bits (85), Expect = 0.084
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 9/109 (8%)
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
QC L E G+ K+ + + H C D C L + F + E K
Sbjct: 131 QCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECL-----EGFRL-AEDGK 184
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDE 366
C D C H E+ C+N Y CKC++GF DG C+ E
Sbjct: 185 RCRRKDVCKSTHHGCEHI-CVNNGNSYICKCSEGFVLAEDGRRCKKCTE 232
>BC008761-1|AAH08761.2| 743|Homo sapiens LTBP3 protein protein.
Length = 743
Score = 107 bits (258), Expect = 9e-23
Identities = 71/206 (34%), Positives = 94/206 (45%), Gaps = 22/206 (10%)
Query: 278 ECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
EC + C DG +C C + C P + S G C+ V+ C G C
Sbjct: 193 ECRDPSSCPDG--KCENKPGSFKC--IACQPGYR-SQGGGACR---DVNECAEGSPCSPG 244
Query: 337 ATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C NL + C C QG+ DG +C DVDEC EAG + C N C N G + CQ
Sbjct: 245 -WCENLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDV----C-DNGICSNTPGSFQCQ 297
Query: 395 CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVD 452
CL GY +D+ +C ++DEC+ D C NT GSY C C G+ G C +D
Sbjct: 298 CLSGYHLSRDRSHCEDIDECDFPAACIGGD--CINTNGSYRCLCPQGHRLVGGRKCQDID 355
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC++ C C N+ G + C C
Sbjct: 356 ECSQDPSLCLPHGACKNLQGSYVCVC 381
Score = 103 bits (246), Expect = 3e-21
Identities = 66/200 (33%), Positives = 90/200 (45%), Gaps = 23/200 (11%)
Query: 287 GNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKY 346
G+ +C P+ +C C+P + S P ++C V+ C CMN Y
Sbjct: 73 GHGECVPGPPDYSCH---CNPGYR-SHPQH--RYCVDVNECEAEPCGPGRGICMNTGGSY 126
Query: 347 TCKCNQGFQ----GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK 402
C CN+G++ G +C D++EC + H C C+N G Y C C GY K
Sbjct: 127 NCHCNRGYRLHVGAGGRSCVDLNECAKP-----HLCGDGGFCINFPGHYKCNCYPGYRLK 181
Query: 403 DKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC-RCRDGYEGD-GYTCMHVDECTEGS 458
C ++DEC + C D C N PGS+ C C+ GY G C V+EC EGS
Sbjct: 182 ASRPPVCEDIDECR-DPSSC-PDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS 239
Query: 459 HTCHHSARCVNIDGGFRCEC 478
C C N+ G FRC C
Sbjct: 240 -PC-SPGWCENLPGSFRCTC 257
Score = 94.3 bits (224), Expect = 1e-18
Identities = 63/210 (30%), Positives = 90/210 (42%), Gaps = 22/210 (10%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
EC C G C C C+ + V G + C ++ C H C +
Sbjct: 106 ECEAEPCGPGRGICMNTGGSYNCH---CNRGYRLHV-GAGGRSCVDLNECAKPHLCGDGG 161
Query: 338 TCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC- 393
C+N Y C C G++ C+D+DEC++ C +C N G + C
Sbjct: 162 FCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS-----CPDG-KCENKPGSFKCI 215
Query: 394 QCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMH 450
C GY + C +V+EC EG+ C + C N PGS+ C C GY DG +C+
Sbjct: 216 ACQPGYRSQGGGACRDVNECAEGSP--C-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 272
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFT 480
VDEC G C + C N G F+C+C +
Sbjct: 273 VDECEAGD-VCDNGI-CSNTPGSFQCQCLS 300
Score = 83.8 bits (198), Expect = 2e-15
Identities = 74/266 (27%), Positives = 106/266 (39%), Gaps = 30/266 (11%)
Query: 223 RCSCVHGEI--TCRPVEC-DRAECKNPVLHP-GEC--CPTCLRQCLLWGNLYEHGERFAP 276
+C+C G RP C D EC++P P G+C P + C+ Y A
Sbjct: 171 KCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFK-CIACQPGYRSQGGGAC 229
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
++ EC +G+ C+ E C Q ++ P + C VD C G CD N
Sbjct: 230 RDVNECA--EGS-PCSPGWCENLPGSFRCTCAQGYA-PAPDGRSCLDVDECEAGDVCD-N 284
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C N + C+C G+ D C+D+DEC G C +N G Y C
Sbjct: 285 GICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDC------INTNGSYRCL 338
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVD 452
C G+ C ++DEC + C C N GSY C C +G+ D + C V+
Sbjct: 339 CPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVE 398
Query: 453 ECTEGSHTCHHSARC-VNIDGGFRCE 477
+ HH C +N D C+
Sbjct: 399 Q-------PHHKKECYLNFDDTVFCD 417
Score = 75.4 bits (177), Expect = 6e-13
Identities = 40/122 (32%), Positives = 56/122 (45%), Gaps = 12/122 (9%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCH 421
+ DEC+ + GH CV Y C C GY + CV+V+ECE G
Sbjct: 61 ETDECRLNQNICGHG-----ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCG-P 114
Query: 422 ADAVCTNTPGSYTCRCRDGYE----GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCE 477
+C NT GSY C C GY G +C+ ++EC + H C C+N G ++C
Sbjct: 115 GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCN 173
Query: 478 CF 479
C+
Sbjct: 174 CY 175
Score = 74.9 bits (176), Expect = 8e-13
Identities = 48/160 (30%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNT 382
D C + + + C+ Y+C CN G++ C DV+EC+ G
Sbjct: 63 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGI---- 118
Query: 383 RCVNVVGGYVCQCLGGY---TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
C+N G Y C C GY +CV+++EC H C C N PG Y C C
Sbjct: 119 -CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKCNCYP 176
Query: 440 GYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY C +DEC + S +C +C N G F+C
Sbjct: 177 GYRLKASRPPVCEDIDECRDPS-SC-PDGKCENKPGSFKC 214
Score = 55.2 bits (127), Expect = 7e-07
Identities = 78/276 (28%), Positives = 99/276 (35%), Gaps = 36/276 (13%)
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGER 273
G RD + C EI C +C N PG C C + GNL E +
Sbjct: 474 GIPAHRDIDECMLFGSEI------CKEGKCVNT--QPGYEC-YCKQGFYYDGNLLECVD- 523
Query: 274 FAPKECA-ECVCHDGNMQCTRVDPELAC-PRLPCDPPQQFSVPGECCKFCPGV-DYCNMG 330
EC E C +G + TR AC P P Q+ + E + P D C
Sbjct: 524 --VDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQ 581
Query: 331 HSCDENATCMNLNTKYT---CKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
D T C C QG +G G C+ C G G HC ++ N
Sbjct: 582 RGEDGMCAGPLAGPALTFDDCCCRQG-RGWGAQCRP---CPPRGA--GSHCPTSQSESNS 635
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT 447
LG R + + + DEC C C PG C C G++ D
Sbjct: 636 FWDTSPLLLGKPPRDEDSSEEDSDECR-----C-VSGRCVPRPGGAVCECPGGFQLDASR 689
Query: 448 --CMHVDECTEGSHT---CHHSARCVNIDGGFRCEC 478
C+ +DEC E + C S RCVN G FRC C
Sbjct: 690 ARCVDIDECRELNQRGLLCK-SERCVNTSGSFRCVC 724
Score = 53.2 bits (122), Expect = 3e-06
Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 5/63 (7%)
Query: 383 RCVNVVGGYVCQCLGGYTRK-DKFNCVEVDEC-EGNTHG--CHADAVCTNTPGSYTCRCR 438
RCV GG VC+C GG+ + CV++DEC E N G C ++ C NT GS+ C C+
Sbjct: 667 RCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER-CVNTSGSFRCVCK 725
Query: 439 DGY 441
G+
Sbjct: 726 AGF 728
Score = 46.0 bits (104), Expect = 4e-04
Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 348 CKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR 401
C+C GFQ D C D+DEC+E G C S RCVN G + C C G+ R
Sbjct: 677 CECPGGFQLDASRARCVDIDECRELNQ-RGLLCKSE-RCVNTSGSFRCVCKAGFAR 730
>AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein.
Length = 1382
Score = 107 bits (258), Expect = 9e-23
Identities = 71/206 (34%), Positives = 94/206 (45%), Gaps = 22/206 (10%)
Query: 278 ECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
EC + C DG +C C + C P + S G C+ V+ C G C
Sbjct: 785 ECRDPSSCPDG--KCENKPGSFKC--IACQPGYR-SQGGGACR---DVNECAEGSPCSPG 836
Query: 337 ATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C NL + C C QG+ DG +C DVDEC EAG + C N C N G + CQ
Sbjct: 837 -WCENLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDV----C-DNGICSNTPGSFQCQ 889
Query: 395 CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVD 452
CL GY +D+ +C ++DEC+ D C NT GSY C C G+ G C +D
Sbjct: 890 CLSGYHLSRDRSHCEDIDECDFPAACIGGD--CINTNGSYRCLCPQGHRLVGGRKCQDID 947
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC++ C C N+ G + C C
Sbjct: 948 ECSQDPSLCLPHGACKNLQGSYVCVC 973
Score = 103 bits (246), Expect = 3e-21
Identities = 66/200 (33%), Positives = 90/200 (45%), Gaps = 23/200 (11%)
Query: 287 GNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKY 346
G+ +C P+ +C C+P + S P ++C V+ C CMN Y
Sbjct: 665 GHGECVPGPPDYSCH---CNPGYR-SHPQH--RYCVDVNECEAEPCGPGRGICMNTGGSY 718
Query: 347 TCKCNQGFQ----GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK 402
C CN+G++ G +C D++EC + H C C+N G Y C C GY K
Sbjct: 719 NCHCNRGYRLHVGAGGRSCVDLNECAKP-----HLCGDGGFCINFPGHYKCNCYPGYRLK 773
Query: 403 DKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC-RCRDGYEGD-GYTCMHVDECTEGS 458
C ++DEC + C D C N PGS+ C C+ GY G C V+EC EGS
Sbjct: 774 ASRPPVCEDIDECR-DPSSC-PDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS 831
Query: 459 HTCHHSARCVNIDGGFRCEC 478
C C N+ G FRC C
Sbjct: 832 -PC-SPGWCENLPGSFRCTC 849
Score = 94.3 bits (224), Expect = 1e-18
Identities = 63/210 (30%), Positives = 90/210 (42%), Gaps = 22/210 (10%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
EC C G C C C+ + V G + C ++ C H C +
Sbjct: 698 ECEAEPCGPGRGICMNTGGSYNCH---CNRGYRLHV-GAGGRSCVDLNECAKPHLCGDGG 753
Query: 338 TCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC- 393
C+N Y C C G++ C+D+DEC++ C +C N G + C
Sbjct: 754 FCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS-----CPDG-KCENKPGSFKCI 807
Query: 394 QCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMH 450
C GY + C +V+EC EG+ C + C N PGS+ C C GY DG +C+
Sbjct: 808 ACQPGYRSQGGGACRDVNECAEGSP--C-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 864
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFT 480
VDEC G C + C N G F+C+C +
Sbjct: 865 VDECEAGD-VCDNGI-CSNTPGSFQCQCLS 892
Score = 83.8 bits (198), Expect = 2e-15
Identities = 74/266 (27%), Positives = 106/266 (39%), Gaps = 30/266 (11%)
Query: 223 RCSCVHGEI--TCRPVEC-DRAECKNPVLHP-GEC--CPTCLRQCLLWGNLYEHGERFAP 276
+C+C G RP C D EC++P P G+C P + C+ Y A
Sbjct: 763 KCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFK-CIACQPGYRSQGGGAC 821
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
++ EC +G+ C+ E C Q ++ P + C VD C G CD N
Sbjct: 822 RDVNECA--EGS-PCSPGWCENLPGSFRCTCAQGYA-PAPDGRSCLDVDECEAGDVCD-N 876
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C N + C+C G+ D C+D+DEC G C +N G Y C
Sbjct: 877 GICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDC------INTNGSYRCL 930
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVD 452
C G+ C ++DEC + C C N GSY C C +G+ D + C V+
Sbjct: 931 CPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVE 990
Query: 453 ECTEGSHTCHHSARC-VNIDGGFRCE 477
+ HH C +N D C+
Sbjct: 991 Q-------PHHKKECYLNFDDTVFCD 1009
Score = 75.4 bits (177), Expect = 6e-13
Identities = 40/122 (32%), Positives = 56/122 (45%), Gaps = 12/122 (9%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCH 421
+ DEC+ + GH CV Y C C GY + CV+V+ECE G
Sbjct: 653 ETDECRLNQNICGHG-----ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCG-P 706
Query: 422 ADAVCTNTPGSYTCRCRDGYE----GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCE 477
+C NT GSY C C GY G +C+ ++EC + H C C+N G ++C
Sbjct: 707 GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCN 765
Query: 478 CF 479
C+
Sbjct: 766 CY 767
Score = 74.9 bits (176), Expect = 8e-13
Identities = 48/160 (30%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNT 382
D C + + + C+ Y+C CN G++ C DV+EC+ G
Sbjct: 655 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGI---- 710
Query: 383 RCVNVVGGYVCQCLGGY---TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
C+N G Y C C GY +CV+++EC H C C N PG Y C C
Sbjct: 711 -CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKCNCYP 768
Query: 440 GYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY C +DEC + S +C +C N G F+C
Sbjct: 769 GYRLKASRPPVCEDIDECRDPS-SC-PDGKCENKPGSFKC 806
Score = 74.5 bits (175), Expect = 1e-12
Identities = 82/306 (26%), Positives = 117/306 (38%), Gaps = 46/306 (15%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVEC-DRAECKNPVLHPGEC 253
+++CD +C ++ +G+ RC C G +C D EC P C
Sbjct: 906 IDECDFPAACIGGDCINTNGSY------RCLCPQGHRLVGGRKCQDIDECSQD---PSLC 956
Query: 254 CPTCLRQCLLWGNLYEHGERFAPKE----CAECVCHDGNMQC-TRVDPELACPRLPCDPP 308
P + L + E F P + C E +C D + C +
Sbjct: 957 LPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNV 1016
Query: 309 QQFSVPGECCKFCPGV-DYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD------GLTC 361
Q CC G D+C + + C ++ C +G+ D G+
Sbjct: 1017 TQQEC---CCSLGAGWGDHCEI-YPCPVYSSA---EFHSLCPDGKGYTQDNNIVNYGIPA 1069
Query: 362 -QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDECEGNTHG 419
+D+DEC L G +CVN GY C C G Y + CV+VDEC ++
Sbjct: 1070 HRDIDECM----LFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN- 1124
Query: 420 CHADAVCTNTPGSYTCRCRDG--YEGDGYTC-----MHVDECTEGSHTCHHSARCVNIDG 472
C + VC NT G Y C C Y C M VDEC + + C RCVN+ G
Sbjct: 1125 CR-NGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPA-ACR-PGRCVNLPG 1181
Query: 473 GFRCEC 478
+RCEC
Sbjct: 1182 SYRCEC 1187
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/125 (36%), Positives = 57/125 (45%), Gaps = 19/125 (15%)
Query: 324 VDYCNM-GHSCDENATCMNLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHS 380
+D C + G + C+N Y C C QGF DG L C DVDEC L +C
Sbjct: 1073 IDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-----LDESNCR- 1126
Query: 381 NTRCVNVVGGYVCQCL--GGYTRKDKFNC-----VEVDECEGNTHGCHADAVCTNTPGSY 433
N C N GGY C C Y+ + C ++VDEC+ + C C N PGSY
Sbjct: 1127 NGVCENTRGGYRCACTPPAEYSPAQR-QCLSPEEMDVDECQ-DPAACRPGR-CVNLPGSY 1183
Query: 434 TCRCR 438
C CR
Sbjct: 1184 RCECR 1188
Score = 53.2 bits (122), Expect = 3e-06
Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 5/63 (7%)
Query: 383 RCVNVVGGYVCQCLGGYTRK-DKFNCVEVDEC-EGNTHG--CHADAVCTNTPGSYTCRCR 438
RCV GG VC+C GG+ + CV++DEC E N G C ++ C NT GS+ C C+
Sbjct: 1306 RCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER-CVNTSGSFRCVCK 1364
Query: 439 DGY 441
G+
Sbjct: 1365 AGF 1367
Score = 52.0 bits (119), Expect = 6e-06
Identities = 43/136 (31%), Positives = 55/136 (40%), Gaps = 18/136 (13%)
Query: 348 CKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC 407
C C QG +G G C+ C G G HC ++ N LG R + +
Sbjct: 1241 CCCRQG-RGWGAQCRP---CPPRGA--GSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSE 1294
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT--CMHVDECTEGSHT---CH 462
+ DEC C C PG C C G++ D C+ +DEC E + C
Sbjct: 1295 EDSDECR-----C-VSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCK 1348
Query: 463 HSARCVNIDGGFRCEC 478
S RCVN G FRC C
Sbjct: 1349 -SERCVNTSGSFRCVC 1363
Score = 46.0 bits (104), Expect = 4e-04
Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 348 CKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR 401
C+C GFQ D C D+DEC+E G C S RCVN G + C C G+ R
Sbjct: 1316 CECPGGFQLDASRARCVDIDECRELNQ-RGLLCKSE-RCVNTSGSFRCVCKAGFAR 1369
Score = 39.5 bits (88), Expect = 0.037
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
Query: 387 VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
V G C GY R + +C +++EC H D C N PGSY C C G+
Sbjct: 412 VRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGD--CLNNPGSYRCVCPPGH 464
>AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming growth
factor beta binding protein 3 protein.
Length = 1256
Score = 107 bits (258), Expect = 9e-23
Identities = 71/206 (34%), Positives = 94/206 (45%), Gaps = 22/206 (10%)
Query: 278 ECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
EC + C DG +C C + C P + S G C+ V+ C G C
Sbjct: 706 ECRDPSSCPDG--KCENKPGSFKC--IACQPGYR-SQGGGACR---DVNECAEGSPCSPG 757
Query: 337 ATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C NL + C C QG+ DG +C DVDEC EAG + C N C N G + CQ
Sbjct: 758 -WCENLPGSFRCTCAQGYAPAPDGRSCLDVDEC-EAGDV----C-DNGICSNTPGSFQCQ 810
Query: 395 CLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE-GDGYTCMHVD 452
CL GY +D+ +C ++DEC+ D C NT GSY C C G+ G C +D
Sbjct: 811 CLSGYHLSRDRSHCEDIDECDFPAACIGGD--CINTNGSYRCLCPQGHRLVGGRKCQDID 868
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCEC 478
EC++ C C N+ G + C C
Sbjct: 869 ECSQDPSLCLPHGACKNLQGSYVCVC 894
Score = 103 bits (246), Expect = 3e-21
Identities = 66/200 (33%), Positives = 90/200 (45%), Gaps = 23/200 (11%)
Query: 287 GNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKY 346
G+ +C P+ +C C+P + S P ++C V+ C CMN Y
Sbjct: 586 GHGECVPGPPDYSCH---CNPGYR-SHPQH--RYCVDVNECEAEPCGPGRGICMNTGGSY 639
Query: 347 TCKCNQGFQ----GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK 402
C CN+G++ G +C D++EC + H C C+N G Y C C GY K
Sbjct: 640 NCHCNRGYRLHVGAGGRSCVDLNECAKP-----HLCGDGGFCINFPGHYKCNCYPGYRLK 694
Query: 403 DKFN--CVEVDECEGNTHGCHADAVCTNTPGSYTC-RCRDGYEGD-GYTCMHVDECTEGS 458
C ++DEC + C D C N PGS+ C C+ GY G C V+EC EGS
Sbjct: 695 ASRPPVCEDIDECR-DPSSC-PDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGS 752
Query: 459 HTCHHSARCVNIDGGFRCEC 478
C C N+ G FRC C
Sbjct: 753 -PC-SPGWCENLPGSFRCTC 770
Score = 94.3 bits (224), Expect = 1e-18
Identities = 63/210 (30%), Positives = 90/210 (42%), Gaps = 22/210 (10%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
EC C G C C C+ + V G + C ++ C H C +
Sbjct: 619 ECEAEPCGPGRGICMNTGGSYNCH---CNRGYRLHV-GAGGRSCVDLNECAKPHLCGDGG 674
Query: 338 TCMNLNTKYTCKCNQGFQGDGL---TCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC- 393
C+N Y C C G++ C+D+DEC++ C +C N G + C
Sbjct: 675 FCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSS-----CPDG-KCENKPGSFKCI 728
Query: 394 QCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTCMH 450
C GY + C +V+EC EG+ C + C N PGS+ C C GY DG +C+
Sbjct: 729 ACQPGYRSQGGGACRDVNECAEGSP--C-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 785
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFT 480
VDEC G C + C N G F+C+C +
Sbjct: 786 VDECEAGD-VCDNGI-CSNTPGSFQCQCLS 813
Score = 83.8 bits (198), Expect = 2e-15
Identities = 74/266 (27%), Positives = 106/266 (39%), Gaps = 30/266 (11%)
Query: 223 RCSCVHGEI--TCRPVEC-DRAECKNPVLHP-GEC--CPTCLRQCLLWGNLYEHGERFAP 276
+C+C G RP C D EC++P P G+C P + C+ Y A
Sbjct: 684 KCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFK-CIACQPGYRSQGGGAC 742
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
++ EC +G+ C+ E C Q ++ P + C VD C G CD N
Sbjct: 743 RDVNECA--EGS-PCSPGWCENLPGSFRCTCAQGYA-PAPDGRSCLDVDECEAGDVCD-N 797
Query: 337 ATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
C N + C+C G+ D C+D+DEC G C +N G Y C
Sbjct: 798 GICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDC------INTNGSYRCL 851
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVD 452
C G+ C ++DEC + C C N GSY C C +G+ D + C V+
Sbjct: 852 CPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVE 911
Query: 453 ECTEGSHTCHHSARC-VNIDGGFRCE 477
+ HH C +N D C+
Sbjct: 912 Q-------PHHKKECYLNFDDTVFCD 930
Score = 75.4 bits (177), Expect = 6e-13
Identities = 40/122 (32%), Positives = 56/122 (45%), Gaps = 12/122 (9%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFN-CVEVDECEGNTHGCH 421
+ DEC+ + GH CV Y C C GY + CV+V+ECE G
Sbjct: 574 ETDECRLNQNICGHG-----ECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCG-P 627
Query: 422 ADAVCTNTPGSYTCRCRDGYE----GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCE 477
+C NT GSY C C GY G +C+ ++EC + H C C+N G ++C
Sbjct: 628 GRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAK-PHLCGDGGFCINFPGHYKCN 686
Query: 478 CF 479
C+
Sbjct: 687 CY 688
Score = 74.9 bits (176), Expect = 8e-13
Identities = 48/160 (30%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNT 382
D C + + + C+ Y+C CN G++ C DV+EC+ G
Sbjct: 576 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGI---- 631
Query: 383 RCVNVVGGYVCQCLGGY---TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
C+N G Y C C GY +CV+++EC H C C N PG Y C C
Sbjct: 632 -CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNEC-AKPHLCGDGGFCINFPGHYKCNCYP 689
Query: 440 GYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GY C +DEC + S +C +C N G F+C
Sbjct: 690 GYRLKASRPPVCEDIDECRDPS-SC-PDGKCENKPGSFKC 727
Score = 55.2 bits (127), Expect = 7e-07
Identities = 78/276 (28%), Positives = 99/276 (35%), Gaps = 36/276 (13%)
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGER 273
G RD + C EI C +C N PG C C + GNL E +
Sbjct: 987 GIPAHRDIDECMLFGSEI------CKEGKCVNT--QPGYEC-YCKQGFYYDGNLLECVD- 1036
Query: 274 FAPKECA-ECVCHDGNMQCTRVDPELAC-PRLPCDPPQQFSVPGECCKFCPGV-DYCNMG 330
EC E C +G + TR AC P P Q+ + E + P D C
Sbjct: 1037 --VDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQ 1094
Query: 331 HSCDENATCMNLNTKYT---CKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV 387
D T C C QG +G G C+ C G G HC ++ N
Sbjct: 1095 RGEDGMCAGPLAGPALTFDDCCCRQG-RGWGAQCRP---CPPRGA--GSHCPTSQSESNS 1148
Query: 388 VGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYT 447
LG R + + + DEC C C PG C C G++ D
Sbjct: 1149 FWDTSPLLLGKPPRDEDSSEEDSDECR-----C-VSGRCVPRPGGAVCECPGGFQLDASR 1202
Query: 448 --CMHVDECTEGSHT---CHHSARCVNIDGGFRCEC 478
C+ +DEC E + C S RCVN G FRC C
Sbjct: 1203 ARCVDIDECRELNQRGLLCK-SERCVNTSGSFRCVC 1237
Score = 53.2 bits (122), Expect = 3e-06
Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 5/63 (7%)
Query: 383 RCVNVVGGYVCQCLGGYTRK-DKFNCVEVDEC-EGNTHG--CHADAVCTNTPGSYTCRCR 438
RCV GG VC+C GG+ + CV++DEC E N G C ++ C NT GS+ C C+
Sbjct: 1180 RCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSER-CVNTSGSFRCVCK 1238
Query: 439 DGY 441
G+
Sbjct: 1239 AGF 1241
Score = 46.0 bits (104), Expect = 4e-04
Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 348 CKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR 401
C+C GFQ D C D+DEC+E G C S RCVN G + C C G+ R
Sbjct: 1190 CECPGGFQLDASRARCVDIDECRELNQ-RGLLCKSE-RCVNTSGSFRCVCKAGFAR 1243
Score = 39.5 bits (88), Expect = 0.037
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
Query: 387 VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
V G C GY R + +C +++EC H D C N PGSY C C G+
Sbjct: 333 VRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGD--CLNNPGSYRCVCPPGH 385
>AK160380-1|BAD18723.1| 1055|Homo sapiens FLJ00344 protein protein.
Length = 1055
Score = 106 bits (255), Expect = 2e-22
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 16/211 (7%)
Query: 273 RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFC-PGVDYCNMGH 331
++ P+ +C+C G R+D + AC C + + C P V +C++
Sbjct: 216 KYGPRCNKKCLCVHGTCN-NRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHI-- 272
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV-VGG 390
+ATC N +C C G++GDG C ++D C GL C N C+N G
Sbjct: 273 ----HATCEYSNGTASCICKAGYEGDGTLCSEMDPCT---GLTPGGCSRNAECINTGTGT 325
Query: 391 YVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC 448
+ C C G+T + +C E++ C + GCH +A C PG C C+ G+ G+G C
Sbjct: 326 HTCVCQQGWTGNGR-DCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC 384
Query: 449 MHVDECTEGSHTCHHSARCVNIDGG-FRCEC 478
+ C E + CH A C + G + C C
Sbjct: 385 EPITSCLEQTGKCHPLASCQSTSSGVWSCVC 415
Score = 91.5 bits (217), Expect = 9e-18
Identities = 49/135 (36%), Positives = 69/135 (51%), Gaps = 13/135 (9%)
Query: 321 CPGVDYCN--MGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDEC--QEAGGLHG 375
C +D C C NA C+N T +TC C QG+ G+G C +++ C AGG
Sbjct: 298 CSEMDPCTGLTPGGCSRNAECINTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGG--- 354
Query: 376 HHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP-GSY 433
CH N C+ V G C+C G+ R + +C + C T CH A C +T G +
Sbjct: 355 --CHDNASCLYVGPGQNECECKKGF-RGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVW 411
Query: 434 TCRCRDGYEGDGYTC 448
+C C++GYEGDG+ C
Sbjct: 412 SCVCQEGYEGDGFLC 426
Score = 91.1 bits (216), Expect = 1e-17
Identities = 52/156 (33%), Positives = 70/156 (44%), Gaps = 10/156 (6%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C D CN +C +A C+ N + +CKC GFQG+G C ++ C+ + G
Sbjct: 857 GVHCDNATTEDNCN--GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNG- 913
Query: 374 HGHHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PG 431
C + C G VC C GYT D C+E++ C N GC +A CT T P
Sbjct: 914 ---GCSAKADCKRTTPGRRVCTCKAGYTG-DGIVCLEINPCLENHCGCDKNAECTQTGPN 969
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
C C Y GDG C ++ C + C A C
Sbjct: 970 QAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC 1005
Score = 83.8 bits (198), Expect = 2e-15
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
C+ + FS G C+ C Y G CD+ +C++ +CNQG GDG DV
Sbjct: 805 CECGEGFS--GTACETCTEGKY---GIHCDQACSCVH------GRCNQGPLGDGSCDCDV 853
Query: 365 D----ECQEAGGLHGHH--CHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
C A + CH++ C+ N G C+C G+ C ++ CE +
Sbjct: 854 GWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTI-CTAINACEISN 912
Query: 418 HGCHADAVCTNT-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GC A A C T PG C C+ GY GDG C+ ++ C E C +A C G +
Sbjct: 913 GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHCGCDKNAECTQ-TGPNQA 971
Query: 477 ECFTENCELSCSWQGRV 493
C NC + + G+V
Sbjct: 972 AC---NCLPAYTGDGKV 985
Score = 77.4 bits (182), Expect = 1e-13
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG N + C N C++ +N C+C +GF G C + C E G
Sbjct: 775 GPQCQPCPG----NAQNVCFGNGICLDGVNGTGVCECGEGF--SGTAC---ETCTE--GK 823
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVC- 426
+G HC CV+ +G C C G+ N D C G CH A C
Sbjct: 824 YGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT---CHTSANCL 880
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
TN+ G+ +C+C G++G+G C ++ C + C A C G R C C
Sbjct: 881 TNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC 933
Score = 71.7 bits (168), Expect = 7e-12
Identities = 53/174 (30%), Positives = 71/174 (40%), Gaps = 14/174 (8%)
Query: 316 ECCK--FCPGVDYCNMGHS--CDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEA 370
+CCK + P + C G S C N C + L TC C +GFQG CQ + +
Sbjct: 160 KCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGS--QCQFCSDPNKY 217
Query: 371 GGLHGHHCHS-NTRCVNVVGGYVCQCLGGYTRKDKFNCV---EVDECEGNTHGCHADAVC 426
G C + C N + CL G R + + C CH A C
Sbjct: 218 GPRCNKKCLCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATC 276
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTE-GSHTCHHSARCVNI-DGGFRCEC 478
+ G+ +C C+ GYEGDG C +D CT C +A C+N G C C
Sbjct: 277 EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECINTGTGTHTCVC 330
Score = 59.3 bits (137), Expect = 4e-08
Identities = 33/122 (27%), Positives = 49/122 (40%), Gaps = 9/122 (7%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
C ++ C + + C A C + C C G+ GDG+ C +++ C E + C
Sbjct: 902 CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLE----NHCGC 957
Query: 379 HSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCR 436
N C C CL YT K C ++ C GC A+C +T TC
Sbjct: 958 DKNAECTQTGPNQAACNCLPAYTGDGKV-CTLINVCLTKNGGCSEFAICNHTGQVERTCT 1016
Query: 437 CR 438
C+
Sbjct: 1017 CK 1018
>X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for
kidney epidermal growth factor (EGF) precursor. ).
Length = 1207
Score = 105 bits (253), Expect = 4e-22
Identities = 47/117 (40%), Positives = 62/117 (52%), Gaps = 8/117 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH- 421
D D+C G C RC++ CQCL G+ K C ++DECE C
Sbjct: 831 DQDDCAPVG------CSMYARCISEGEDATCQCLKGFAGDGKL-CSDIDECEMGVPVCPP 883
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
A + C NT G Y CRC +GY+GDG C+ +DEC G H+C +A C N +GG+ C C
Sbjct: 884 ASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMC 940
Score = 105 bits (252), Expect = 5e-22
Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 6/117 (5%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH-SNTRCVNVVGGY 391
C A C++ TC+C +GF GDG C D+DEC+ + C ++++C+N GGY
Sbjct: 840 CSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPV----CPPASSKCINTEGGY 895
Query: 392 VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC 448
VC+C GY + D +C+++DEC+ H C +A CTNT G YTC C G C
Sbjct: 896 VCRCSEGY-QGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLIC 951
Score = 63.3 bits (147), Expect = 3e-09
Identities = 36/102 (35%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+T C + ++C C GY +D+ C +V+EC HGC C NTPGSY C C
Sbjct: 326 SSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG--CKNTPGSYYCTCP 383
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ DG C + C C H CV G C C
Sbjct: 384 VGFVLLPDGKRCHQLVSCPRNVSECSHD--CVLTSEGPLCFC 423
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 18/125 (14%)
Query: 252 ECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDP-ELACPRLPCDPPQQ 310
+C P C ++ GE A +C + DG + C+ +D E+ P P +
Sbjct: 834 DCAPV---GCSMYARCISEGED-ATCQCLKGFAGDGKL-CSDIDECEMGVPVCPPASSKC 888
Query: 311 FSVPG----ECCK-------FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDG 358
+ G C + C +D C +G HSC ENA+C N YTC C G
Sbjct: 889 INTEGGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPG 948
Query: 359 LTCQD 363
L C D
Sbjct: 949 LICPD 953
Score = 31.5 bits (68), Expect = 9.7
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVD 452
D C GC + +C G+ C CR+G+ DG TC+ +D
Sbjct: 743 DPCLYQNGGC--EHICKKRLGTAWCSCREGFMKASDGKTCLALD 784
>BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor
(beta-urogastrone) protein.
Length = 1207
Score = 105 bits (253), Expect = 4e-22
Identities = 47/117 (40%), Positives = 62/117 (52%), Gaps = 8/117 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH- 421
D D+C G C RC++ CQCL G+ K C ++DECE C
Sbjct: 831 DQDDCAPVG------CSMYARCISEGEDATCQCLKGFAGDGKL-CSDIDECEMGVPVCPP 883
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
A + C NT G Y CRC +GY+GDG C+ +DEC G H+C +A C N +GG+ C C
Sbjct: 884 ASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMC 940
Score = 105 bits (252), Expect = 5e-22
Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 6/117 (5%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH-SNTRCVNVVGGY 391
C A C++ TC+C +GF GDG C D+DEC+ + C ++++C+N GGY
Sbjct: 840 CSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPV----CPPASSKCINTEGGY 895
Query: 392 VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC 448
VC+C GY + D +C+++DEC+ H C +A CTNT G YTC C G C
Sbjct: 896 VCRCSEGY-QGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLIC 951
Score = 63.3 bits (147), Expect = 3e-09
Identities = 36/102 (35%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+T C + ++C C GY +D+ C +V+EC HGC C NTPGSY C C
Sbjct: 326 SSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG--CKNTPGSYYCTCP 383
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ DG C + C C H CV G C C
Sbjct: 384 VGFVLLPDGKRCHQLVSCPRNVSECSHD--CVLTSEGPLCFC 423
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 18/125 (14%)
Query: 252 ECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDP-ELACPRLPCDPPQQ 310
+C P C ++ GE A +C + DG + C+ +D E+ P P +
Sbjct: 834 DCAPV---GCSMYARCISEGED-ATCQCLKGFAGDGKL-CSDIDECEMGVPVCPPASSKC 888
Query: 311 FSVPG----ECCK-------FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDG 358
+ G C + C +D C +G HSC ENA+C N YTC C G
Sbjct: 889 INTEGGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPG 948
Query: 359 LTCQD 363
L C D
Sbjct: 949 LICPD 953
Score = 31.5 bits (68), Expect = 9.7
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVD 452
D C GC + +C G+ C CR+G+ DG TC+ +D
Sbjct: 743 DPCLYQNGGC--EHICKKRLGTAWCSCREGFMKASDGKTCLALD 784
>BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor
(beta-urogastrone) protein.
Length = 1207
Score = 105 bits (253), Expect = 4e-22
Identities = 47/117 (40%), Positives = 62/117 (52%), Gaps = 8/117 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH- 421
D D+C G C RC++ CQCL G+ K C ++DECE C
Sbjct: 831 DQDDCAPVG------CSMYARCISEGEDATCQCLKGFAGDGKL-CSDIDECEMGVPVCPP 883
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
A + C NT G Y CRC +GY+GDG C+ +DEC G H+C +A C N +GG+ C C
Sbjct: 884 ASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMC 940
Score = 105 bits (252), Expect = 5e-22
Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 6/117 (5%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH-SNTRCVNVVGGY 391
C A C++ TC+C +GF GDG C D+DEC+ + C ++++C+N GGY
Sbjct: 840 CSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPV----CPPASSKCINTEGGY 895
Query: 392 VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC 448
VC+C GY + D +C+++DEC+ H C +A CTNT G YTC C G C
Sbjct: 896 VCRCSEGY-QGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLIC 951
Score = 63.3 bits (147), Expect = 3e-09
Identities = 36/102 (35%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+T C + ++C C GY +D+ C +V+EC HGC C NTPGSY C C
Sbjct: 326 SSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG--CKNTPGSYYCTCP 383
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ DG C + C C H CV G C C
Sbjct: 384 VGFVLLPDGKRCHQLVSCPRNVSECSHD--CVLTSEGPLCFC 423
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 18/125 (14%)
Query: 252 ECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDP-ELACPRLPCDPPQQ 310
+C P C ++ GE A +C + DG + C+ +D E+ P P +
Sbjct: 834 DCAPV---GCSMYARCISEGED-ATCQCLKGFAGDGKL-CSDIDECEMGVPVCPPASSKC 888
Query: 311 FSVPG----ECCK-------FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDG 358
+ G C + C +D C +G HSC ENA+C N YTC C G
Sbjct: 889 INTEGGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPG 948
Query: 359 LTCQD 363
L C D
Sbjct: 949 LICPD 953
Score = 31.5 bits (68), Expect = 9.7
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVD 452
D C GC + +C G+ C CR+G+ DG TC+ +D
Sbjct: 743 DPCLYQNGGC--EHICKKRLGTAWCSCREGFMKASDGKTCLALD 784
>AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal growth
factor (beta-urogastrone) protein.
Length = 1152
Score = 105 bits (253), Expect = 4e-22
Identities = 47/117 (40%), Positives = 62/117 (52%), Gaps = 8/117 (6%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH- 421
D D+C G C RC++ CQCL G+ K C ++DECE C
Sbjct: 831 DQDDCAPVG------CSMYARCISEGEDATCQCLKGFAGDGKL-CSDIDECEMGVPVCPP 883
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
A + C NT G Y CRC +GY+GDG C+ +DEC G H+C +A C N +GG+ C C
Sbjct: 884 ASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMC 940
Score = 105 bits (252), Expect = 5e-22
Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 6/117 (5%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCH-SNTRCVNVVGGY 391
C A C++ TC+C +GF GDG C D+DEC+ + C ++++C+N GGY
Sbjct: 840 CSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPV----CPPASSKCINTEGGY 895
Query: 392 VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC 448
VC+C GY + D +C+++DEC+ H C +A CTNT G YTC C G C
Sbjct: 896 VCRCSEGY-QGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPGLIC 951
Score = 63.3 bits (147), Expect = 3e-09
Identities = 36/102 (35%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
S+T C + ++C C GY +D+ C +V+EC HGC C NTPGSY C C
Sbjct: 326 SSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG--CKNTPGSYYCTCP 383
Query: 439 DGYE--GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+ DG C + C C H CV G C C
Sbjct: 384 VGFVLLPDGKRCHQLVSCPRNVSECSHD--CVLTSEGPLCFC 423
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 18/125 (14%)
Query: 252 ECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDP-ELACPRLPCDPPQQ 310
+C P C ++ GE A +C + DG + C+ +D E+ P P +
Sbjct: 834 DCAPV---GCSMYARCISEGED-ATCQCLKGFAGDGKL-CSDIDECEMGVPVCPPASSKC 888
Query: 311 FSVPG----ECCK-------FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDG 358
+ G C + C +D C +G HSC ENA+C N YTC C G
Sbjct: 889 INTEGGYVCRCSEGYQGDGIHCLDIDECQLGVHSCGENASCTNTEGGYTCMCAGRLSEPG 948
Query: 359 LTCQD 363
L C D
Sbjct: 949 LICPD 953
Score = 31.5 bits (68), Expect = 9.7
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVD 452
D C GC + +C G+ C CR+G+ DG TC+ +D
Sbjct: 743 DPCLYQNGGC--EHICKKRLGTAWCSCREGFMKASDGKTCLALD 784
>AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein.
Length = 2551
Score = 105 bits (251), Expect = 6e-22
Identities = 53/144 (36%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C +ATC NT C+CN ++GDG+TC VD C++ G C RC
Sbjct: 2055 CSAHATCKENNT---CECNLDYEGDGITCTVVDFCKQDNG----GCAKVARCSQKGTKVS 2107
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC-- 448
C C GY + D +C E+D C +G GCH A C T PG + C C+ Y GDG C
Sbjct: 2108 CSCQKGY-KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 2166
Query: 449 --MHVDECTEGSHTCHHSARCVNI 470
+ +D C + + CH A+CV++
Sbjct: 2167 EQLPIDRCLQDNGQCHADAKCVDL 2190
Score = 104 bits (249), Expect = 1e-21
Identities = 61/211 (28%), Positives = 95/211 (45%), Gaps = 16/211 (7%)
Query: 273 RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFC-PGVDYCNMGH 331
++ P+ +C+C G R+D + AC C + + C P V +C++
Sbjct: 783 KYGPRCNKKCLCVHGTCN-NRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHI-- 839
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV-VGG 390
+ATC N +C C G++GDG C ++D C GL C N C+ G
Sbjct: 840 ----HATCEYSNGTASCICKAGYEGDGTLCSEMDPCT---GLTPGGCSRNAECIKTGTGT 892
Query: 391 YVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC 448
+ C C G+T + +C E++ C + GCH +A C PG C C+ G+ G+G C
Sbjct: 893 HTCVCQQGWTGNGR-DCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC 951
Query: 449 MHVDECTEGSHTCHHSARCVNIDGG-FRCEC 478
+ C E + CH A C + G + C C
Sbjct: 952 EPITSCLEQTGKCHPLASCQSTSSGVWSCVC 982
Score = 91.5 bits (217), Expect = 9e-18
Identities = 52/156 (33%), Positives = 70/156 (44%), Gaps = 10/156 (6%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C D CN +C +A C+ N + +CKC GFQG+G C ++ C+ + G
Sbjct: 1424 GVHCDNATTEDNCN--GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNG- 1480
Query: 374 HGHHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PG 431
C + C G VC C GYT D C+E++ C N GC +A CT T P
Sbjct: 1481 ---GCSAKADCKRTTPGRRVCTCKAGYTG-DGIVCLEINPCLENHGGCDKNAECTQTGPN 1536
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
C C Y GDG C ++ C + C A C
Sbjct: 1537 QAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC 1572
Score = 89.0 bits (211), Expect = 5e-17
Identities = 48/135 (35%), Positives = 68/135 (50%), Gaps = 13/135 (9%)
Query: 321 CPGVDYCN--MGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDEC--QEAGGLHG 375
C +D C C NA C+ T +TC C QG+ G+G C +++ C AGG
Sbjct: 865 CSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGG--- 921
Query: 376 HHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP-GSY 433
CH N C+ V G C+C G+ R + +C + C T CH A C +T G +
Sbjct: 922 --CHDNASCLYVGPGQNECECKKGF-RGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVW 978
Query: 434 TCRCRDGYEGDGYTC 448
+C C++GYEGDG+ C
Sbjct: 979 SCVCQEGYEGDGFLC 993
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
C+ + FS G C+ C Y G CD+ +C++ +CNQG GDG DV
Sbjct: 1372 CECGEGFS--GTACETCTEGKY---GIHCDQACSCVH------GRCNQGPLGDGSCDCDV 1420
Query: 365 D----ECQEAGGLHGHH--CHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
C A + CH++ C+ N G C+C G+ C ++ CE +
Sbjct: 1421 GWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTI-CTAINACEISN 1479
Query: 418 HGCHADAVCTNT-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GC A A C T PG C C+ GY GDG C+ ++ C E C +A C G +
Sbjct: 1480 GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQ-TGPNQA 1538
Query: 477 ECFTENCELSCSWQGRV 493
C NC + + G+V
Sbjct: 1539 AC---NCLPAYTGDGKV 1552
Score = 77.4 bits (182), Expect = 1e-13
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG N + C N C++ +N C+C +GF G C + C E G
Sbjct: 1342 GPQCQPCPG----NAQNVCFGNGICLDGVNGTGVCECGEGF--SGTAC---ETCTE--GK 1390
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVC- 426
+G HC CV+ +G C C G+ N D C G CH A C
Sbjct: 1391 YGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT---CHTSANCL 1447
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
TN+ G+ +C+C G++G+G C ++ C + C A C G R C C
Sbjct: 1448 TNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC 1500
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
C ++ C + + C A C + C C G+ GDG+ C +++ C E HG C
Sbjct: 1469 CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLEN---HGG-C 1524
Query: 379 HSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCR 436
N C C CL YT K C ++ C GC A+C +T TC
Sbjct: 1525 DKNAECTQTGPNQAACNCLPAYTGDGKV-CTLINVCLTKNGGCSEFAICNHTGQVERTCT 1583
Query: 437 CRDGYEGDGYTC 448
C+ Y GDG+TC
Sbjct: 1584 CKPNYIGDGFTC 1595
Score = 74.9 bits (176), Expect = 8e-13
Identities = 57/179 (31%), Positives = 84/179 (46%), Gaps = 23/179 (12%)
Query: 278 ECAECVCHDGNMQC---TRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCD 334
ECA +C + N +C T + +L C LP + G K+C ++ C + C
Sbjct: 198 ECAALLCPE-NSRCSPSTEDENKLECKCLP-----NYRGDG---KYCDPINPC-LRKICH 247
Query: 335 ENATCMNLN-TKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS-NTRC-VNVVGGY 391
+A C L +++C C +G++GDG C VD CQ G +C + +T C + G
Sbjct: 248 PHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFG----NCPTKSTVCKYDGPGQS 303
Query: 392 VCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC 448
C+C Y C D C+ + + CH +A CT PG C C+ GY GDG TC
Sbjct: 304 HCECKEHYQNFVPGVGCSMTDICKSD-NPCHRNANCTTVAPGRTECICQKGYVGDGLTC 361
Score = 69.3 bits (162), Expect = 4e-11
Identities = 52/174 (29%), Positives = 70/174 (40%), Gaps = 14/174 (8%)
Query: 316 ECCK--FCPGVDYCNMGHS--CDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEA 370
+CCK + P + C G S C N C + L TC C +GFQG CQ + +
Sbjct: 727 KCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGS--QCQFCSDPNKY 784
Query: 371 GGLHGHHCHS-NTRCVNVVGGYVCQCLGGYTRKDKFNCV---EVDECEGNTHGCHADAVC 426
G C + C N + CL G R + + C CH A C
Sbjct: 785 GPRCNKKCLCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATC 843
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTE-GSHTCHHSARCVNI-DGGFRCEC 478
+ G+ +C C+ GYEGDG C +D CT C +A C+ G C C
Sbjct: 844 EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVC 897
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 18/171 (10%)
Query: 315 GECCKFC-PG---VDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQE 369
G C+ C PG D G C ++ C + + C C G+ G Q V
Sbjct: 1994 GTACEMCWPGRFGPDCLPCG--CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAV----- 2046
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
+ C ++ C C+C Y D C VD C+ + GC A C+
Sbjct: 2047 LPAVCTPPCSAHATCKE---NNTCECNLDY-EGDGITCTVVDFCKQDNGGCAKVARCSQK 2102
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEG-SHTCHHSARC-VNIDGGFRCEC 478
+C C+ GY+GDG++C +D C +G + CH A C + G +CEC
Sbjct: 2103 GTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCEC 2153
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/173 (27%), Positives = 68/173 (39%), Gaps = 18/173 (10%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN------LNTKYTCKCNQGFQGDGLTCQDVDECQ 368
G C+ C D G SC C++ L+ TC+C + G + + EC
Sbjct: 144 GTACETC--ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCD-KPIPECA 200
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C +T N + C+CL Y K+ C ++ C CH A CT
Sbjct: 201 ALLCPENSRCSPSTEDENKLE---CKCLPNYRGDGKY-CDPINPCLRKI--CHPHAHCTY 254
Query: 429 T-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNID--GGFRCEC 478
P ++C C++GY GDG C+ VD C C + D G CEC
Sbjct: 255 LGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCEC 307
Score = 61.3 bits (142), Expect = 1e-08
Identities = 48/167 (28%), Positives = 64/167 (38%), Gaps = 15/167 (8%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C+ C++ + CKCN GF +G C+ +
Sbjct: 1956 GRDCQACPG----GPDAPCNNRGVCLDQYSATGECKCNTGF--NGTACEMCWPGRFGPDC 2009
Query: 374 HGHHCHSNTRCVN-VVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPG 431
C + +C + + G C C G+T V C T C A A C
Sbjct: 2010 LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVC---TPPCSAHATCKE--- 2063
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ TC C YEGDG TC VD C + + C ARC C C
Sbjct: 2064 NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSC 2110
Score = 53.6 bits (123), Expect = 2e-06
Identities = 51/177 (28%), Positives = 65/177 (36%), Gaps = 33/177 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGL-TCQDVDECQEAGG 372
G C CPG G C+ +C + TC C +GF G TC D
Sbjct: 106 GPDCIECPG----GAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCAD-------DN 154
Query: 373 LHGHHCHSNTRCVNVV------GGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADA 424
L G C S CV+ V G C+C YT + DK + EC C ++
Sbjct: 155 LFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDK----PIPECAALL--CPENS 208
Query: 425 VC---TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C T C+C Y GDG C ++ C CH A C + G R C
Sbjct: 209 RCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLR--KICHPHAHCTYL-GPNRHSC 262
Score = 37.1 bits (82), Expect = 0.20
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 286 DGNMQCTRVDP-ELACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLN 343
D N +CT+ P + AC LP ++ G+ C ++ C C E A C +
Sbjct: 1525 DKNAECTQTGPNQAACNCLPA-----YTGDGKVCTL---INVCLTKNGGCSEFAICNHTG 1576
Query: 344 -TKYTCKCNQGFQGDGLTCQ 362
+ TC C + GDG TC+
Sbjct: 1577 QVERTCTCKPNYIGDGFTCR 1596
Score = 31.5 bits (68), Expect = 9.7
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Query: 412 ECEGNTHG-CHADAVCTN-TPGSYTCRCRDGYEGDG-YTC----MHVDECTEGSHTCHHS 464
EC G C+ C G+ TC C++G+ G TC + C+ + C H
Sbjct: 111 ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCN-CVHG 169
Query: 465 ARCVNIDGGFRCECFT 480
+DG CEC++
Sbjct: 170 VCNSGLDGDGTCECYS 185
>AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for
endocytosis precursor protein.
Length = 1416
Score = 105 bits (251), Expect = 6e-22
Identities = 53/144 (36%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C +ATC NT C+CN ++GDG+TC VD C++ G C RC
Sbjct: 920 CSAHATCKENNT---CECNLDYEGDGITCTVVDFCKQDNG----GCAKVARCSQKGTKVS 972
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC-- 448
C C GY + D +C E+D C +G GCH A C T PG + C C+ Y GDG C
Sbjct: 973 CSCQKGY-KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 1031
Query: 449 --MHVDECTEGSHTCHHSARCVNI 470
+ +D C + + CH A+CV++
Sbjct: 1032 EQLPIDRCLQDNGQCHADAKCVDL 1055
Score = 89.8 bits (213), Expect = 3e-17
Identities = 52/156 (33%), Positives = 69/156 (44%), Gaps = 10/156 (6%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C D CN +C +A C+ N + +CKC GFQG+G C ++ C+ + G
Sbjct: 289 GVHCDNATTEDNCN--GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNG- 345
Query: 374 HGHHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PG 431
C + C G VC C GYT D C+E++ C N GC +A CT T P
Sbjct: 346 ---GCSAKADCKRTTPGRRVCTCKAGYTG-DGIVCLEINPCLENHGGCDKNAECTQTGPN 401
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
C C Y GDG C + C + C A C
Sbjct: 402 QAACNCLPAYTGDGKVCTLIYVCLTKNGGCSEFAIC 437
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
C+ + FS G C+ C Y G CD+ +C++ +CNQG GDG DV
Sbjct: 237 CECGEGFS--GTACETCTEGKY---GIHCDQACSCVH------GRCNQGPLGDGSCDCDV 285
Query: 365 D----ECQEAGGLHGHH--CHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
C A + CH++ C+ N G C+C G+ C ++ CE +
Sbjct: 286 GWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTI-CTAINACEISN 344
Query: 418 HGCHADAVCTNT-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GC A A C T PG C C+ GY GDG C+ ++ C E C +A C G +
Sbjct: 345 GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQ-TGPNQA 403
Query: 477 ECFTENCELSCSWQGRV 493
C NC + + G+V
Sbjct: 404 AC---NCLPAYTGDGKV 417
Score = 77.4 bits (182), Expect = 1e-13
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG N + C N C++ +N C+C +GF G C + C E G
Sbjct: 207 GPQCQPCPG----NAQNVCFGNGICLDGVNGTGVCECGEGF--SGTAC---ETCTE--GK 255
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVC- 426
+G HC CV+ +G C C G+ N D C G CH A C
Sbjct: 256 YGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT---CHTSANCL 312
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
TN+ G+ +C+C G++G+G C ++ C + C A C G R C C
Sbjct: 313 TNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC 365
Score = 75.8 bits (178), Expect = 5e-13
Identities = 41/132 (31%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
C ++ C + + C A C + C C G+ GDG+ C +++ C E HG C
Sbjct: 334 CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLEN---HGG-C 389
Query: 379 HSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCR 436
N C C CL YT K C + C GC A+C +T TC
Sbjct: 390 DKNAECTQTGPNQAACNCLPAYTGDGKV-CTLIYVCLTKNGGCSEFAICNHTGQVERTCT 448
Query: 437 CRDGYEGDGYTC 448
C+ Y GDG+TC
Sbjct: 449 CKPNYIGDGFTC 460
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 18/171 (10%)
Query: 315 GECCKFC-PG---VDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQE 369
G C+ C PG D G C ++ C + + C C G+ G Q V
Sbjct: 859 GTACEMCWPGRFGPDCLPCG--CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAV----- 911
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
+ C ++ C C+C Y D C VD C+ + GC A C+
Sbjct: 912 LPAVCTPPCSAHATCKE---NNTCECNLDY-EGDGITCTVVDFCKQDNGGCAKVARCSQK 967
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEG-SHTCHHSARC-VNIDGGFRCEC 478
+C C+ GY+GDG++C +D C +G + CH A C + G +CEC
Sbjct: 968 GTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCEC 1018
Score = 61.3 bits (142), Expect = 1e-08
Identities = 48/167 (28%), Positives = 64/167 (38%), Gaps = 15/167 (8%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C+ C++ + CKCN GF +G C+ +
Sbjct: 821 GRDCQACPG----GPDAPCNNRGVCLDQYSATGECKCNTGF--NGTACEMCWPGRFGPDC 874
Query: 374 HGHHCHSNTRCVN-VVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPG 431
C + +C + + G C C G+T V C T C A A C
Sbjct: 875 LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVC---TPPCSAHATCKE--- 928
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ TC C YEGDG TC VD C + + C ARC C C
Sbjct: 929 NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSC 975
Score = 35.5 bits (78), Expect = 0.60
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Query: 286 DGNMQCTRVDP-ELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLN- 343
D N +CT+ P + AC LP ++ G+ C N G C E A C +
Sbjct: 390 DKNAECTQTGPNQAACNCLPA-----YTGDGKVCTLIYVCLTKNGG--CSEFAICNHTGQ 442
Query: 344 TKYTCKCNQGFQGDGLTCQ 362
+ TC C + GDG TC+
Sbjct: 443 VERTCTCKPNYIGDGFTCR 461
>AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein.
Length = 1736
Score = 105 bits (251), Expect = 6e-22
Identities = 53/144 (36%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C +ATC NT C+CN ++GDG+TC VD C++ G C RC
Sbjct: 1240 CSAHATCKENNT---CECNLDYEGDGITCTVVDFCKQDNG----GCAKVARCSQKGTKVS 1292
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC-- 448
C C GY + D +C E+D C +G GCH A C T PG + C C+ Y GDG C
Sbjct: 1293 CSCQKGY-KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 1351
Query: 449 --MHVDECTEGSHTCHHSARCVNI 470
+ +D C + + CH A+CV++
Sbjct: 1352 EQLPIDRCLQDNGQCHADAKCVDL 1375
Score = 97.9 bits (233), Expect = 1e-19
Identities = 49/150 (32%), Positives = 71/150 (47%), Gaps = 8/150 (5%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV-VGGY 391
C +ATC N +C C G++GDG C ++D C GL C N C+ G +
Sbjct: 22 CHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCT---GLTPGGCSRNAECIKTGTGTH 78
Query: 392 VCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTCM 449
C C G+T + +C E++ C + GCH +A C PG C C+ G+ G+G C
Sbjct: 79 TCVCQQGWTGNGR-DCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCE 137
Query: 450 HVDECTEGSHTCHHSARCVNIDGG-FRCEC 478
+ C E + CH A C + G + C C
Sbjct: 138 PITSCLEQTGKCHPLASCQSTSSGVWSCVC 167
Score = 91.5 bits (217), Expect = 9e-18
Identities = 52/156 (33%), Positives = 70/156 (44%), Gaps = 10/156 (6%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C D CN +C +A C+ N + +CKC GFQG+G C ++ C+ + G
Sbjct: 609 GVHCDNATTEDNCN--GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNG- 665
Query: 374 HGHHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PG 431
C + C G VC C GYT D C+E++ C N GC +A CT T P
Sbjct: 666 ---GCSAKADCKRTTPGRRVCTCKAGYTG-DGIVCLEINPCLENHGGCDKNAECTQTGPN 721
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
C C Y GDG C ++ C + C A C
Sbjct: 722 QAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC 757
Score = 89.0 bits (211), Expect = 5e-17
Identities = 48/135 (35%), Positives = 68/135 (50%), Gaps = 13/135 (9%)
Query: 321 CPGVDYCN--MGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDEC--QEAGGLHG 375
C +D C C NA C+ T +TC C QG+ G+G C +++ C AGG
Sbjct: 50 CSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGG--- 106
Query: 376 HHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP-GSY 433
CH N C+ V G C+C G+ R + +C + C T CH A C +T G +
Sbjct: 107 --CHDNASCLYVGPGQNECECKKGF-RGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVW 163
Query: 434 TCRCRDGYEGDGYTC 448
+C C++GYEGDG+ C
Sbjct: 164 SCVCQEGYEGDGFLC 178
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
C+ + FS G C+ C Y G CD+ +C++ +CNQG GDG DV
Sbjct: 557 CECGEGFS--GTACETCTEGKY---GIHCDQACSCVH------GRCNQGPLGDGSCDCDV 605
Query: 365 D----ECQEAGGLHGHH--CHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
C A + CH++ C+ N G C+C G+ C ++ CE +
Sbjct: 606 GWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTI-CTAINACEISN 664
Query: 418 HGCHADAVCTNT-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GC A A C T PG C C+ GY GDG C+ ++ C E C +A C G +
Sbjct: 665 GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQ-TGPNQA 723
Query: 477 ECFTENCELSCSWQGRV 493
C NC + + G+V
Sbjct: 724 AC---NCLPAYTGDGKV 737
Score = 77.4 bits (182), Expect = 1e-13
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG N + C N C++ +N C+C +GF G C + C E G
Sbjct: 527 GPQCQPCPG----NAQNVCFGNGICLDGVNGTGVCECGEGF--SGTAC---ETCTE--GK 575
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVC- 426
+G HC CV+ +G C C G+ N D C G CH A C
Sbjct: 576 YGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT---CHTSANCL 632
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
TN+ G+ +C+C G++G+G C ++ C + C A C G R C C
Sbjct: 633 TNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC 685
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
C ++ C + + C A C + C C G+ GDG+ C +++ C E HG C
Sbjct: 654 CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLEN---HGG-C 709
Query: 379 HSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCR 436
N C C CL YT K C ++ C GC A+C +T TC
Sbjct: 710 DKNAECTQTGPNQAACNCLPAYTGDGKV-CTLINVCLTKNGGCSEFAICNHTGQVERTCT 768
Query: 437 CRDGYEGDGYTC 448
C+ Y GDG+TC
Sbjct: 769 CKPNYIGDGFTC 780
Score = 71.7 bits (168), Expect = 7e-12
Identities = 42/126 (33%), Positives = 59/126 (46%), Gaps = 5/126 (3%)
Query: 357 DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGN 416
DG + D+ A G + CH + C G C C GY D C E+D C G
Sbjct: 1 DGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGY-EGDGTLCSEMDPCTGL 59
Query: 417 T-HGCHADAVCTNT-PGSYTCRCRDGYEGDGYTCMHVDEC-TEGSHTCHHSARCVNI-DG 472
T GC +A C T G++TC C+ G+ G+G C ++ C + CH +A C+ + G
Sbjct: 60 TPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPG 119
Query: 473 GFRCEC 478
CEC
Sbjct: 120 QNECEC 125
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 18/171 (10%)
Query: 315 GECCKFC-PG---VDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQE 369
G C+ C PG D G C ++ C + + C C G+ G Q V
Sbjct: 1179 GTACEMCWPGRFGPDCLPCG--CSDHGQCDDGITGSGQCLCETGWTGTSCDTQAV----- 1231
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
+ C ++ C C+C Y D C VD C+ + GC A C+
Sbjct: 1232 LPAVCTPPCSAHATCKE---NNTCECNLDY-EGDGITCTVVDFCKQDNGGCAKVARCSQK 1287
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEG-SHTCHHSARC-VNIDGGFRCEC 478
+C C+ GY+GDG++C +D C +G + CH A C + G +CEC
Sbjct: 1288 GTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCEC 1338
Score = 37.1 bits (82), Expect = 0.20
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 286 DGNMQCTRVDP-ELACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLN 343
D N +CT+ P + AC LP ++ G+ C ++ C C E A C +
Sbjct: 710 DKNAECTQTGPNQAACNCLPA-----YTGDGKVCTL---INVCLTKNGGCSEFAICNHTG 761
Query: 344 -TKYTCKCNQGFQGDGLTCQ 362
+ TC C + GDG TC+
Sbjct: 762 QVERTCTCKPNYIGDGFTCR 781
>AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein.
Length = 1192
Score = 105 bits (251), Expect = 6e-22
Identities = 53/144 (36%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C +ATC NT C+CN ++GDG+TC VD C++ G C RC
Sbjct: 696 CSAHATCKENNT---CECNLDYEGDGITCTVVDFCKQDNG----GCAKVARCSQKGTKVS 748
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC-- 448
C C GY + D +C E+D C +G GCH A C T PG + C C+ Y GDG C
Sbjct: 749 CSCQKGY-KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 807
Query: 449 --MHVDECTEGSHTCHHSARCVNI 470
+ +D C + + CH A+CV++
Sbjct: 808 EQLPIDRCLQDNGQCHADAKCVDL 831
Score = 91.5 bits (217), Expect = 9e-18
Identities = 52/156 (33%), Positives = 70/156 (44%), Gaps = 10/156 (6%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C D CN +C +A C+ N + +CKC GFQG+G C ++ C+ + G
Sbjct: 65 GVHCDNATTEDNCN--GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNG- 121
Query: 374 HGHHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PG 431
C + C G VC C GYT D C+E++ C N GC +A CT T P
Sbjct: 122 ---GCSAKADCKRTTPGRRVCTCKAGYTG-DGIVCLEINPCLENHGGCDKNAECTQTGPN 177
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
C C Y GDG C ++ C + C A C
Sbjct: 178 QAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC 213
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
C+ + FS G C+ C Y G CD+ +C++ +CNQG GDG DV
Sbjct: 13 CECGEGFS--GTACETCTEGKY---GIHCDQACSCVH------GRCNQGPLGDGSCDCDV 61
Query: 365 D----ECQEAGGLHGHH--CHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
C A + CH++ C+ N G C+C G+ C ++ CE +
Sbjct: 62 GWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTI-CTAINACEISN 120
Query: 418 HGCHADAVCTNT-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GC A A C T PG C C+ GY GDG C+ ++ C E C +A C G +
Sbjct: 121 GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQ-TGPNQA 179
Query: 477 ECFTENCELSCSWQGRV 493
C NC + + G+V
Sbjct: 180 AC---NCLPAYTGDGKV 193
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
C ++ C + + C A C + C C G+ GDG+ C +++ C E HG C
Sbjct: 110 CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLEN---HGG-C 165
Query: 379 HSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCR 436
N C C CL YT K C ++ C GC A+C +T TC
Sbjct: 166 DKNAECTQTGPNQAACNCLPAYTGDGKV-CTLINVCLTKNGGCSEFAICNHTGQVERTCT 224
Query: 437 CRDGYEGDGYTC 448
C+ Y GDG+TC
Sbjct: 225 CKPNYIGDGFTC 236
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 18/171 (10%)
Query: 315 GECCKFC-PG---VDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQE 369
G C+ C PG D G C ++ C + + C C G+ G Q V
Sbjct: 635 GTACEMCWPGRFGPDCLPCG--CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAV----- 687
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
+ C ++ C C+C Y D C VD C+ + GC A C+
Sbjct: 688 LPAVCTPPCSAHATCKE---NNTCECNLDY-EGDGITCTVVDFCKQDNGGCAKVARCSQK 743
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEG-SHTCHHSARC-VNIDGGFRCEC 478
+C C+ GY+GDG++C +D C +G + CH A C + G +CEC
Sbjct: 744 GTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCEC 794
Score = 61.3 bits (142), Expect = 1e-08
Identities = 48/167 (28%), Positives = 64/167 (38%), Gaps = 15/167 (8%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C+ C++ + CKCN GF +G C+ +
Sbjct: 597 GRDCQACPG----GPDAPCNNRGVCLDQYSATGECKCNTGF--NGTACEMCWPGRFGPDC 650
Query: 374 HGHHCHSNTRCVN-VVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPG 431
C + +C + + G C C G+T V C T C A A C
Sbjct: 651 LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVC---TPPCSAHATCKE--- 704
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ TC C YEGDG TC VD C + + C ARC C C
Sbjct: 705 NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSC 751
Score = 37.1 bits (82), Expect = 0.20
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 286 DGNMQCTRVDP-ELACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLN 343
D N +CT+ P + AC LP ++ G+ C ++ C C E A C +
Sbjct: 166 DKNAECTQTGPNQAACNCLPA-----YTGDGKVCTL---INVCLTKNGGCSEFAICNHTG 217
Query: 344 -TKYTCKCNQGFQGDGLTCQ 362
+ TC C + GDG TC+
Sbjct: 218 QVERTCTCKPNYIGDGFTCR 237
>AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein.
Length = 2551
Score = 105 bits (251), Expect = 6e-22
Identities = 53/144 (36%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C +ATC NT C+CN ++GDG+TC VD C++ G C RC
Sbjct: 2055 CSAHATCKENNT---CECNLDYEGDGITCTVVDFCKQDNG----GCAKVARCSQKGTKVS 2107
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC-- 448
C C GY + D +C E+D C +G GCH A C T PG + C C+ Y GDG C
Sbjct: 2108 CSCQKGY-KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 2166
Query: 449 --MHVDECTEGSHTCHHSARCVNI 470
+ +D C + + CH A+CV++
Sbjct: 2167 EQLPIDRCLQDNGQCHADAKCVDL 2190
Score = 104 bits (249), Expect = 1e-21
Identities = 61/211 (28%), Positives = 95/211 (45%), Gaps = 16/211 (7%)
Query: 273 RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFC-PGVDYCNMGH 331
++ P+ +C+C G R+D + AC C + + C P V +C++
Sbjct: 783 KYGPRCNKKCLCVHGTCN-NRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHI-- 839
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV-VGG 390
+ATC N +C C G++GDG C ++D C GL C N C+ G
Sbjct: 840 ----HATCEYSNGTASCICKAGYEGDGTLCSEMDPCT---GLTPGGCSRNAECIKTGTGT 892
Query: 391 YVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC 448
+ C C G+T + +C E++ C + GCH +A C PG C C+ G+ G+G C
Sbjct: 893 HTCVCQQGWTGNGR-DCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC 951
Query: 449 MHVDECTEGSHTCHHSARCVNIDGG-FRCEC 478
+ C E + CH A C + G + C C
Sbjct: 952 EPITSCLEQTGKCHPLASCQSTSSGVWSCVC 982
Score = 91.5 bits (217), Expect = 9e-18
Identities = 52/156 (33%), Positives = 70/156 (44%), Gaps = 10/156 (6%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C D CN +C +A C+ N + +CKC GFQG+G C ++ C+ + G
Sbjct: 1424 GVHCDNATTEDNCN--GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNG- 1480
Query: 374 HGHHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PG 431
C + C G VC C GYT D C+E++ C N GC +A CT T P
Sbjct: 1481 ---GCSAKADCKRTTPGRRVCTCKAGYTG-DGIVCLEINPCLENHGGCDKNAECTQTGPN 1536
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
C C Y GDG C ++ C + C A C
Sbjct: 1537 QAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC 1572
Score = 89.0 bits (211), Expect = 5e-17
Identities = 48/135 (35%), Positives = 68/135 (50%), Gaps = 13/135 (9%)
Query: 321 CPGVDYCN--MGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDEC--QEAGGLHG 375
C +D C C NA C+ T +TC C QG+ G+G C +++ C AGG
Sbjct: 865 CSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGG--- 921
Query: 376 HHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP-GSY 433
CH N C+ V G C+C G+ R + +C + C T CH A C +T G +
Sbjct: 922 --CHDNASCLYVGPGQNECECKKGF-RGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVW 978
Query: 434 TCRCRDGYEGDGYTC 448
+C C++GYEGDG+ C
Sbjct: 979 SCVCQEGYEGDGFLC 993
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
C+ + FS G C+ C Y G CD+ +C++ +CNQG GDG DV
Sbjct: 1372 CECGEGFS--GTACETCTEGKY---GIHCDQACSCVH------GRCNQGPLGDGSCDCDV 1420
Query: 365 D----ECQEAGGLHGHH--CHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
C A + CH++ C+ N G C+C G+ C ++ CE +
Sbjct: 1421 GWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTI-CTAINACEISN 1479
Query: 418 HGCHADAVCTNT-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GC A A C T PG C C+ GY GDG C+ ++ C E C +A C G +
Sbjct: 1480 GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQ-TGPNQA 1538
Query: 477 ECFTENCELSCSWQGRV 493
C NC + + G+V
Sbjct: 1539 AC---NCLPAYTGDGKV 1552
Score = 77.4 bits (182), Expect = 1e-13
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG N + C N C++ +N C+C +GF G C + C E G
Sbjct: 1342 GPQCQPCPG----NAQNVCFGNGICLDGVNGTGVCECGEGF--SGTAC---ETCTE--GK 1390
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVC- 426
+G HC CV+ +G C C G+ N D C G CH A C
Sbjct: 1391 YGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT---CHTSANCL 1447
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
TN+ G+ +C+C G++G+G C ++ C + C A C G R C C
Sbjct: 1448 TNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC 1500
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
C ++ C + + C A C + C C G+ GDG+ C +++ C E HG C
Sbjct: 1469 CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLEN---HGG-C 1524
Query: 379 HSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCR 436
N C C CL YT K C ++ C GC A+C +T TC
Sbjct: 1525 DKNAECTQTGPNQAACNCLPAYTGDGKV-CTLINVCLTKNGGCSEFAICNHTGQVERTCT 1583
Query: 437 CRDGYEGDGYTC 448
C+ Y GDG+TC
Sbjct: 1584 CKPNYIGDGFTC 1595
Score = 74.9 bits (176), Expect = 8e-13
Identities = 57/179 (31%), Positives = 84/179 (46%), Gaps = 23/179 (12%)
Query: 278 ECAECVCHDGNMQC---TRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCD 334
ECA +C + N +C T + +L C LP + G K+C ++ C + C
Sbjct: 198 ECAALLCPE-NSRCSPSTEDENKLECKCLP-----NYRGDG---KYCDPINPC-LRKICH 247
Query: 335 ENATCMNLN-TKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS-NTRC-VNVVGGY 391
+A C L +++C C +G++GDG C VD CQ G +C + +T C + G
Sbjct: 248 PHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFG----NCPTKSTVCKYDGPGQS 303
Query: 392 VCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC 448
C+C Y C D C+ + + CH +A CT PG C C+ GY GDG TC
Sbjct: 304 HCECKEHYQNFVPGVGCSMTDICKSD-NPCHRNANCTTVAPGRTECICQKGYVGDGLTC 361
Score = 69.3 bits (162), Expect = 4e-11
Identities = 52/174 (29%), Positives = 70/174 (40%), Gaps = 14/174 (8%)
Query: 316 ECCK--FCPGVDYCNMGHS--CDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEA 370
+CCK + P + C G S C N C + L TC C +GFQG CQ + +
Sbjct: 727 KCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGS--QCQFCSDPNKY 784
Query: 371 GGLHGHHCHS-NTRCVNVVGGYVCQCLGGYTRKDKFNCV---EVDECEGNTHGCHADAVC 426
G C + C N + CL G R + + C CH A C
Sbjct: 785 GPRCNKKCLCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATC 843
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTE-GSHTCHHSARCVNI-DGGFRCEC 478
+ G+ +C C+ GYEGDG C +D CT C +A C+ G C C
Sbjct: 844 EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVC 897
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 18/171 (10%)
Query: 315 GECCKFC-PG---VDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQE 369
G C+ C PG D G C ++ C + + C C G+ G Q V
Sbjct: 1994 GTACEMCWPGRFGPDCLPCG--CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAV----- 2046
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
+ C ++ C C+C Y D C VD C+ + GC A C+
Sbjct: 2047 LPAVCTPPCSAHATCKE---NNTCECNLDY-EGDGITCTVVDFCKQDNGGCAKVARCSQK 2102
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEG-SHTCHHSARC-VNIDGGFRCEC 478
+C C+ GY+GDG++C +D C +G + CH A C + G +CEC
Sbjct: 2103 GTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCEC 2153
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/173 (27%), Positives = 68/173 (39%), Gaps = 18/173 (10%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN------LNTKYTCKCNQGFQGDGLTCQDVDECQ 368
G C+ C D G SC C++ L+ TC+C + G + + EC
Sbjct: 144 GTACETC--ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCD-KPIPECA 200
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C +T N + C+CL Y K+ C ++ C CH A CT
Sbjct: 201 ALLCPENSRCSPSTEDENKLE---CKCLPNYRGDGKY-CDPINPCLRKI--CHPHAHCTY 254
Query: 429 T-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNID--GGFRCEC 478
P ++C C++GY GDG C+ VD C C + D G CEC
Sbjct: 255 LGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCEC 307
Score = 61.3 bits (142), Expect = 1e-08
Identities = 48/167 (28%), Positives = 64/167 (38%), Gaps = 15/167 (8%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C+ C++ + CKCN GF +G C+ +
Sbjct: 1956 GRDCQACPG----GPDAPCNNRGVCLDQYSATGECKCNTGF--NGTACEMCWPGRFGPDC 2009
Query: 374 HGHHCHSNTRCVN-VVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPG 431
C + +C + + G C C G+T V C T C A A C
Sbjct: 2010 LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVC---TPPCSAHATCKE--- 2063
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ TC C YEGDG TC VD C + + C ARC C C
Sbjct: 2064 NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSC 2110
Score = 53.6 bits (123), Expect = 2e-06
Identities = 51/177 (28%), Positives = 65/177 (36%), Gaps = 33/177 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGL-TCQDVDECQEAGG 372
G C CPG G C+ +C + TC C +GF G TC D
Sbjct: 106 GPDCIECPG----GAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCAD-------DN 154
Query: 373 LHGHHCHSNTRCVNVV------GGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADA 424
L G C S CV+ V G C+C YT + DK + EC C ++
Sbjct: 155 LFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDK----PIPECAALL--CPENS 208
Query: 425 VC---TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C T C+C Y GDG C ++ C CH A C + G R C
Sbjct: 209 RCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLR--KICHPHAHCTYL-GPNRHSC 262
Score = 37.1 bits (82), Expect = 0.20
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 286 DGNMQCTRVDP-ELACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLN 343
D N +CT+ P + AC LP ++ G+ C ++ C C E A C +
Sbjct: 1525 DKNAECTQTGPNQAACNCLPA-----YTGDGKVCTL---INVCLTKNGGCSEFAICNHTG 1576
Query: 344 -TKYTCKCNQGFQGDGLTCQ 362
+ TC C + GDG TC+
Sbjct: 1577 QVERTCTCKPNYIGDGFTCR 1596
Score = 31.5 bits (68), Expect = 9.7
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Query: 412 ECEGNTHG-CHADAVCTN-TPGSYTCRCRDGYEGDG-YTC----MHVDECTEGSHTCHHS 464
EC G C+ C G+ TC C++G+ G TC + C+ + C H
Sbjct: 111 ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCN-CVHG 169
Query: 465 ARCVNIDGGFRCECFT 480
+DG CEC++
Sbjct: 170 VCNSGLDGDGTCECYS 185
>AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FELL
protein.
Length = 897
Score = 105 bits (251), Expect = 6e-22
Identities = 53/144 (36%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C +ATC NT C+CN ++GDG+TC VD C++ G C RC
Sbjct: 401 CSAHATCKENNT---CECNLDYEGDGITCTVVDFCKQDNG----GCAKVARCSQKGTKVS 453
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC-- 448
C C GY + D +C E+D C +G GCH A C T PG + C C+ Y GDG C
Sbjct: 454 CSCQKGY-KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 512
Query: 449 --MHVDECTEGSHTCHHSARCVNI 470
+ +D C + + CH A+CV++
Sbjct: 513 EQLPIDRCLQDNGQCHADAKCVDL 536
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 18/171 (10%)
Query: 315 GECCKFC-PG---VDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQE 369
G C+ C PG D G C ++ C + + C C G+ G Q V
Sbjct: 340 GTACEMCWPGRFGPDCLPCG--CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAV----- 392
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
+ C ++ C C+C Y D C VD C+ + GC A C+
Sbjct: 393 LPAVCTPPCSAHATCKE---NNTCECNLDY-EGDGITCTVVDFCKQDNGGCAKVARCSQK 448
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEG-SHTCHHSARC-VNIDGGFRCEC 478
+C C+ GY+GDG++C +D C +G + CH A C + G +CEC
Sbjct: 449 GTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCEC 499
Score = 61.3 bits (142), Expect = 1e-08
Identities = 48/167 (28%), Positives = 64/167 (38%), Gaps = 15/167 (8%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C+ C++ + CKCN GF +G C+ +
Sbjct: 302 GRDCQACPG----GPDAPCNNRGVCLDQYSATGECKCNTGF--NGTACEMCWPGRFGPDC 355
Query: 374 HGHHCHSNTRCVN-VVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPG 431
C + +C + + G C C G+T V C T C A A C
Sbjct: 356 LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVC---TPPCSAHATCKE--- 409
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ TC C YEGDG TC VD C + + C ARC C C
Sbjct: 410 NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSC 456
>AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein.
Length = 2551
Score = 105 bits (251), Expect = 6e-22
Identities = 53/144 (36%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C +ATC NT C+CN ++GDG+TC VD C++ G C RC
Sbjct: 2055 CSAHATCKENNT---CECNLDYEGDGITCTVVDFCKQDNG----GCAKVARCSQKGTKVS 2107
Query: 393 CQCLGGYTRKDKFNCVEVDEC-EGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC-- 448
C C GY + D +C E+D C +G GCH A C T PG + C C+ Y GDG C
Sbjct: 2108 CSCQKGY-KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 2166
Query: 449 --MHVDECTEGSHTCHHSARCVNI 470
+ +D C + + CH A+CV++
Sbjct: 2167 EQLPIDRCLQDNGQCHADAKCVDL 2190
Score = 104 bits (249), Expect = 1e-21
Identities = 61/211 (28%), Positives = 95/211 (45%), Gaps = 16/211 (7%)
Query: 273 RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFC-PGVDYCNMGH 331
++ P+ +C+C G R+D + AC C + + C P V +C++
Sbjct: 783 KYGPRCNKKCLCVHGTCN-NRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHI-- 839
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV-VGG 390
+ATC N +C C G++GDG C ++D C GL C N C+ G
Sbjct: 840 ----HATCEYSNGTASCICKAGYEGDGTLCSEMDPCT---GLTPGGCSRNAECIKTGTGT 892
Query: 391 YVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC 448
+ C C G+T + +C E++ C + GCH +A C PG C C+ G+ G+G C
Sbjct: 893 HTCVCQQGWTGNGR-DCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC 951
Query: 449 MHVDECTEGSHTCHHSARCVNIDGG-FRCEC 478
+ C E + CH A C + G + C C
Sbjct: 952 EPITSCLEQTGKCHPLASCQSTSSGVWSCVC 982
Score = 91.5 bits (217), Expect = 9e-18
Identities = 52/156 (33%), Positives = 70/156 (44%), Gaps = 10/156 (6%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCM-NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C D CN +C +A C+ N + +CKC GFQG+G C ++ C+ + G
Sbjct: 1424 GVHCDNATTEDNCN--GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNG- 1480
Query: 374 HGHHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT-PG 431
C + C G VC C GYT D C+E++ C N GC +A CT T P
Sbjct: 1481 ---GCSAKADCKRTTPGRRVCTCKAGYTG-DGIVCLEINPCLENHGGCDKNAECTQTGPN 1536
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
C C Y GDG C ++ C + C A C
Sbjct: 1537 QAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC 1572
Score = 89.0 bits (211), Expect = 5e-17
Identities = 48/135 (35%), Positives = 68/135 (50%), Gaps = 13/135 (9%)
Query: 321 CPGVDYCN--MGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDEC--QEAGGLHG 375
C +D C C NA C+ T +TC C QG+ G+G C +++ C AGG
Sbjct: 865 CSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGG--- 921
Query: 376 HHCHSNTRCVNVVGGY-VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP-GSY 433
CH N C+ V G C+C G+ R + +C + C T CH A C +T G +
Sbjct: 922 --CHDNASCLYVGPGQNECECKKGF-RGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVW 978
Query: 434 TCRCRDGYEGDGYTC 448
+C C++GYEGDG+ C
Sbjct: 979 SCVCQEGYEGDGFLC 993
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
C+ + FS G C+ C Y G CD+ +C++ +CNQG GDG DV
Sbjct: 1372 CECGEGFS--GTACETCTEGKY---GIHCDQACSCVH------GRCNQGPLGDGSCDCDV 1420
Query: 365 D----ECQEAGGLHGHH--CHSNTRCV-NVVGGYVCQCLGGYTRKDKFNCVEVDECEGNT 417
C A + CH++ C+ N G C+C G+ C ++ CE +
Sbjct: 1421 GWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTI-CTAINACEISN 1479
Query: 418 HGCHADAVCTNT-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRC 476
GC A A C T PG C C+ GY GDG C+ ++ C E C +A C G +
Sbjct: 1480 GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQ-TGPNQA 1538
Query: 477 ECFTENCELSCSWQGRV 493
C NC + + G+V
Sbjct: 1539 AC---NCLPAYTGDGKV 1552
Score = 77.4 bits (182), Expect = 1e-13
Identities = 53/173 (30%), Positives = 75/173 (43%), Gaps = 23/173 (13%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG N + C N C++ +N C+C +GF G C + C E G
Sbjct: 1342 GPQCQPCPG----NAQNVCFGNGICLDGVNGTGVCECGEGF--SGTAC---ETCTE--GK 1390
Query: 374 HGHHCHSNTRCVN------VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVC- 426
+G HC CV+ +G C C G+ N D C G CH A C
Sbjct: 1391 YGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT---CHTSANCL 1447
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR-CEC 478
TN+ G+ +C+C G++G+G C ++ C + C A C G R C C
Sbjct: 1448 TNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC 1500
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 321 CPGVDYCNMGHS-CDENATCMNLNT-KYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
C ++ C + + C A C + C C G+ GDG+ C +++ C E HG C
Sbjct: 1469 CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLEN---HGG-C 1524
Query: 379 HSNTRCVNVVGGYV-CQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG-SYTCR 436
N C C CL YT K C ++ C GC A+C +T TC
Sbjct: 1525 DKNAECTQTGPNQAACNCLPAYTGDGKV-CTLINVCLTKNGGCSEFAICNHTGQVERTCT 1583
Query: 437 CRDGYEGDGYTC 448
C+ Y GDG+TC
Sbjct: 1584 CKPNYIGDGFTC 1595
Score = 74.9 bits (176), Expect = 8e-13
Identities = 57/179 (31%), Positives = 84/179 (46%), Gaps = 23/179 (12%)
Query: 278 ECAECVCHDGNMQC---TRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCD 334
ECA +C + N +C T + +L C LP + G K+C ++ C + C
Sbjct: 198 ECAALLCPE-NSRCSPSTEDENKLECKCLP-----NYRGDG---KYCDPINPC-LRKICH 247
Query: 335 ENATCMNLN-TKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHS-NTRC-VNVVGGY 391
+A C L +++C C +G++GDG C VD CQ G +C + +T C + G
Sbjct: 248 PHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFG----NCPTKSTVCKYDGPGQS 303
Query: 392 VCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNT-PGSYTCRCRDGYEGDGYTC 448
C+C Y C D C+ + + CH +A CT PG C C+ GY GDG TC
Sbjct: 304 HCECKEHYQNFVPGVGCSMTDICKSD-NPCHRNANCTTVAPGRTECICQKGYVGDGLTC 361
Score = 69.3 bits (162), Expect = 4e-11
Identities = 52/174 (29%), Positives = 70/174 (40%), Gaps = 14/174 (8%)
Query: 316 ECCK--FCPGVDYCNMGHS--CDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEA 370
+CCK + P + C G S C N C + L TC C +GFQG CQ + +
Sbjct: 727 KCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGS--QCQFCSDPNKY 784
Query: 371 GGLHGHHCHS-NTRCVNVVGGYVCQCLGGYTRKDKFNCV---EVDECEGNTHGCHADAVC 426
G C + C N + CL G R + + C CH A C
Sbjct: 785 GPRCNKKCLCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATC 843
Query: 427 TNTPGSYTCRCRDGYEGDGYTCMHVDECTE-GSHTCHHSARCVNI-DGGFRCEC 478
+ G+ +C C+ GYEGDG C +D CT C +A C+ G C C
Sbjct: 844 EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVC 897
Score = 69.3 bits (162), Expect = 4e-11
Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 18/171 (10%)
Query: 315 GECCKFC-PG---VDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQE 369
G C+ C PG D G C ++ C + + C C G+ G Q V
Sbjct: 1994 GTACEMCWPGRFGPDCLPCG--CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAV----- 2046
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNT 429
+ C ++ C C+C Y D C VD C+ + GC A C+
Sbjct: 2047 LPAVCTPPCSAHATCKE---NNTCECNLDY-EGDGITCTVVDFCKQDNGGCAKVARCSQK 2102
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEG-SHTCHHSARC-VNIDGGFRCEC 478
+C C+ GY+GDG++C +D C +G + CH A C + G +CEC
Sbjct: 2103 GTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCEC 2153
Score = 65.7 bits (153), Expect = 5e-10
Identities = 48/173 (27%), Positives = 68/173 (39%), Gaps = 18/173 (10%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN------LNTKYTCKCNQGFQGDGLTCQDVDECQ 368
G C+ C D G SC C++ L+ TC+C + G + + EC
Sbjct: 144 GTACETC--ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCD-KPIPECA 200
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTN 428
C +T N + C+CL Y K+ C ++ C CH A CT
Sbjct: 201 ALLCPENSRCSPSTEDENKLE---CKCLPNYRGDGKY-CDPINPCLRKI--CHPHAHCTY 254
Query: 429 T-PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNID--GGFRCEC 478
P ++C C++GY GDG C+ VD C C + D G CEC
Sbjct: 255 LGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCEC 307
Score = 61.3 bits (142), Expect = 1e-08
Identities = 48/167 (28%), Positives = 64/167 (38%), Gaps = 15/167 (8%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
G C+ CPG C+ C++ + CKCN GF +G C+ +
Sbjct: 1956 GRDCQACPG----GPDAPCNNRGVCLDQYSATGECKCNTGF--NGTACEMCWPGRFGPDC 2009
Query: 374 HGHHCHSNTRCVN-VVGGYVCQCLGGYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPG 431
C + +C + + G C C G+T V C T C A A C
Sbjct: 2010 LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVC---TPPCSAHATCKE--- 2063
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ TC C YEGDG TC VD C + + C ARC C C
Sbjct: 2064 NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSC 2110
Score = 53.6 bits (123), Expect = 2e-06
Identities = 51/177 (28%), Positives = 65/177 (36%), Gaps = 33/177 (18%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMN-LNTKYTCKCNQGFQGDGL-TCQDVDECQEAGG 372
G C CPG G C+ +C + TC C +GF G TC D
Sbjct: 106 GPDCIECPG----GAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCAD-------DN 154
Query: 373 LHGHHCHSNTRCVNVV------GGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADA 424
L G C S CV+ V G C+C YT + DK + EC C ++
Sbjct: 155 LFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDK----PIPECAALL--CPENS 208
Query: 425 VC---TNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C T C+C Y GDG C ++ C CH A C + G R C
Sbjct: 209 RCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLR--KICHPHAHCTYL-GPNRHSC 262
Score = 37.1 bits (82), Expect = 0.20
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 286 DGNMQCTRVDP-ELACPRLPCDPPQQFSVPGECCKFCPGVDYC-NMGHSCDENATCMNLN 343
D N +CT+ P + AC LP ++ G+ C ++ C C E A C +
Sbjct: 1525 DKNAECTQTGPNQAACNCLPA-----YTGDGKVCTL---INVCLTKNGGCSEFAICNHTG 1576
Query: 344 -TKYTCKCNQGFQGDGLTCQ 362
+ TC C + GDG TC+
Sbjct: 1577 QVERTCTCKPNYIGDGFTCR 1596
Score = 31.5 bits (68), Expect = 9.7
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Query: 412 ECEGNTHG-CHADAVCTN-TPGSYTCRCRDGYEGDG-YTC----MHVDECTEGSHTCHHS 464
EC G C+ C G+ TC C++G+ G TC + C+ + C H
Sbjct: 111 ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCN-CVHG 169
Query: 465 ARCVNIDGGFRCECFT 480
+DG CEC++
Sbjct: 170 VCNSGLDGDGTCECYS 185
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 104 bits (250), Expect = 9e-22
Identities = 59/155 (38%), Positives = 80/155 (51%), Gaps = 18/155 (11%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
CN G +CD N +N K C C G+ G + QDVDEC L + C +C+N
Sbjct: 381 CNEGSNCDTNP----VNGKAICTCPSGYTGPACS-QDVDECS----LGANPCEHAGKCIN 431
Query: 387 VVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+G + CQCL GYT C ++V+EC N C DA C + G + C C GYEG
Sbjct: 432 TLGSFECQCLQGYTGP---RCEIDVNECVSNP--CQNDATCLDQIGEFQCMCMPGYEG-V 485
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ ++ DEC S C H+ RC++ F+CEC T
Sbjct: 486 HCEVNTDEC--ASSPCLHNGRCLDKINEFQCECPT 518
Score = 99.1 bits (236), Expect = 4e-20
Identities = 81/282 (28%), Positives = 114/282 (40%), Gaps = 37/282 (13%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGEITC-RP-VECDRAECKNPVLHPGECCPT--CLR 259
C GT H + +++ C C H C RP V C + C+N G C PT
Sbjct: 189 CRHGGTCHNEVGSYR--CV-CRATHTGPNCERPYVPCSPSPCQNG----GTCRPTGDVTH 241
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
+C +C C +G C CP C PP+ G+ C
Sbjct: 242 ECACLPGFTGQNCEENIDDCPGNNCKNGGA-CVDGVNTYNCP---C-PPEW---TGQYCT 293
Query: 320 FCPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
VD C M ++C TC N + Y C C G+ G+ + +++D+C A HG C
Sbjct: 294 --EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS-ENIDDCASAACFHGATC 350
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP--GSYTCR 436
H V + C+C G T C D C N C+ + C P G C
Sbjct: 351 HDR------VASFYCECPHGRTG---LLCHLNDACISNP--CNEGSNCDTNPVNGKAICT 399
Query: 437 CRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C GY G + VDEC+ G++ C H+ +C+N G F C+C
Sbjct: 400 CPSGYTGPACS-QDVDECSLGANPCEHAGKCINTLGSFECQC 440
Score = 88.2 bits (209), Expect = 8e-17
Identities = 64/214 (29%), Positives = 92/214 (42%), Gaps = 35/214 (16%)
Query: 279 CAECVCHDGNMQC--TRVDPELACPR----LPCDPPQQFSVPGECCKFCPGVDYCNMGHS 332
C C +G +C T CP L CD P SV E GVD +
Sbjct: 1064 CDSSPCKNGG-KCWQTHTQYRCECPSGWTGLYCDVP---SVSCEVAAQRQGVDVARL--- 1116
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C C++ + C+C G+ G C+D VDEC + C + C + +GGY
Sbjct: 1117 CQHGGLCVDAGNTHHCRCQAGYTGS--YCEDLVDECSPSP------CQNGATCTDYLGGY 1168
Query: 392 VCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
C+C+ GY NC E+DEC +H C C + P +Y C C G +G + ++
Sbjct: 1169 SCKCVAGY---HGVNCSEEIDEC--LSHPCQNGGTCLDLPNTYKCSCPRGTQG-VHCEIN 1222
Query: 451 VDEC------TEGSHTCHHSARCVNIDGGFRCEC 478
VD+C S C ++ CV+ GG+ C C
Sbjct: 1223 VDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC 1256
Score = 79.4 bits (187), Expect = 4e-14
Identities = 47/164 (28%), Positives = 72/164 (43%), Gaps = 13/164 (7%)
Query: 333 CDENATCMNL-NTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C TC + + C C GF G +++D+C G++C + CV+ V Y
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCE-ENIDDCP------GNNCKNGGACVDGVNTY 279
Query: 392 VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV 451
C C +T ++ +VDEC+ + C C NT G Y C C +G+ G+ + ++
Sbjct: 280 NCPCPPEWT--GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS-ENI 336
Query: 452 DECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
D+C S C H A C + F CEC L C +S
Sbjct: 337 DDCA--SAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Score = 79.4 bits (187), Expect = 4e-14
Identities = 75/287 (26%), Positives = 116/287 (40%), Gaps = 32/287 (11%)
Query: 198 CDCQKS-CYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP 255
CD + C SN V+ C+C G + + + EC NP L+ G C
Sbjct: 750 CDINNNECESNPCVNGGTCKDMTSGIVCTCREG-FSGPNCQTNINECASNPCLNKGTCID 808
Query: 256 TCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
CLL AP CA C +G +C + + + C P
Sbjct: 809 DVAGYKCNCLLPYTGATCEVVLAP--CAPSPCRNGG-ECRQSEDYES---FSCVCPTA-G 861
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAG 371
G+ C+ ++ C + C A+C N + Y C C G+ G C+ D+D+C+
Sbjct: 862 AKGQTCEV--DINECVLS-PCRHGASCQNTHGXYRCHCQAGYSGRN--CETDIDDCRP-- 914
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+ CH+ C + + C CL G+ + F +++EC + C A CT+
Sbjct: 915 ----NPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVD 966
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SYTC C G+ G + + +CTE S C + CV+ F C C
Sbjct: 967 SYTCTCPAGFSGI-HCENNTPDCTESS--CFNGGTCVDGINSFTCLC 1010
Score = 76.6 bits (180), Expect = 3e-13
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 19/176 (10%)
Query: 314 PGECCKFC-PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGG 372
PG C +D C G+ C TC + +TC+C +G+ D +V+EC
Sbjct: 668 PGYTGSMCNSNIDEC-AGNPCHNGGTCEDGINGFTCRCPEGYH-DPTCLSEVNECNSNPC 725
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPG 431
+HG C + + GY C C G++ NC + +ECE N C C +
Sbjct: 726 VHG-------ACRDSLNGYKCDCDPGWSGT---NCDINNNECESNP--CVNGGTCKDMTS 773
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
C CR+G+ G +++EC S+ C + C++ G++C C +C
Sbjct: 774 GIVCTCREGFSGPNCQT-NINECA--SNPCLNKGTCIDDVAGYKCNCLLPYTGATC 826
Score = 75.8 bits (178), Expect = 5e-13
Identities = 47/156 (30%), Positives = 77/156 (49%), Gaps = 18/156 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNT 382
V+ C + + C +ATC++ ++ C C G++G + C+ + DEC + LH N
Sbjct: 453 VNEC-VSNPCQNDATCLDQIGEFQCMCMPGYEG--VHCEVNTDECASSPCLH------NG 503
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
RC++ + + C+C G+T +VDEC C A C + P +YTC C +GY
Sbjct: 504 RCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGYT 559
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + + +DEC CH+ + C + F C C
Sbjct: 560 GT-HCEVDIDEC--DPDPCHYGS-CKDGVATFTCLC 591
Score = 75.4 bits (177), Expect = 6e-13
Identities = 49/162 (30%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGG--LHGHHCHS 380
+D C + H C TC++L Y C C +G Q G+ C+ +VD+C C +
Sbjct: 1185 IDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQ--GVHCEINVDDCNPPVDPVSRSPKCFN 1241
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
N CV+ VGGY C C G+ + C +V+EC N C + C CR
Sbjct: 1242 NGTCVDQVGGYSCTCPPGFVGE---RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1298
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCV---NIDGGFRCEC 478
G+ G C V +G C + C N GF C+C
Sbjct: 1299 GH--TGRRCESVINGCKGK-PCKNGGTCAVASNTARGFICKC 1337
Score = 73.7 bits (173), Expect = 2e-12
Identities = 75/294 (25%), Positives = 113/294 (38%), Gaps = 35/294 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNP 246
G + + + +C + NG DG + C C G T E D EC
Sbjct: 519 GFTGHLCQYDVDECASTPCKNGAKCLDGP----NTYTCVCTEG-YTGTHCEVDIDECDPD 573
Query: 247 VLHPGECCP-TCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPC 305
H G C CL H EC+ C ++ T DP+ A C
Sbjct: 574 PCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCR---LRGTCQDPDNA---YLC 627
Query: 306 DPPQQFSVPGECCKFCP-GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
F + G C +D C CD + TC++ Y C C G+ G + ++
Sbjct: 628 -----FCLKGTTGPNCEINLDDC-ASSPCD-SGTCLDKIDGYECACEPGYTGS-MCNSNI 679
Query: 365 DECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADA 424
DEC G+ CH+ C + + G+ C+C GY D EV+EC N++ C
Sbjct: 680 DECA------GNPCHNGGTCEDGINGFTCRCPEGY--HDPTCLSEVNEC--NSNPC-VHG 728
Query: 425 VCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C ++ Y C C G+ G ++ +EC S+ C + C ++ G C C
Sbjct: 729 ACRDSLNGYKCDCDPGWSGTNCD-INNNECE--SNPCVNGGTCKDMTSGIVCTC 779
Score = 66.1 bits (154), Expect = 4e-10
Identities = 77/300 (25%), Positives = 113/300 (37%), Gaps = 38/300 (12%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCL 258
DC+ + NG DG + C C+ G E D EC + G C C+
Sbjct: 911 DCRPNPCHNGGSCTDGI----NTAFCDCLPG-FRGTFCEEDINECASDPCRNGANCTDCV 965
Query: 259 RQ--CLLWGNLYE-HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPG 315
C H E P +C E C +G T VD C P F+ G
Sbjct: 966 DSYTCTCPAGFSGIHCENNTP-DCTESSCFNGG---TCVD---GINSFTCLCPPGFT--G 1016
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
C+ V+ C+ C TC + + C C QG+ G CQ+ V C +
Sbjct: 1017 SYCQHV--VNECD-SRPCLLGGTCQDGRGLHRCTCPQGYTGPN--CQNLVHWCDSSP--- 1068
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRK----DKFNCVEVDECEGNTHG--CHADAVCTN 428
C + +C Y C+C G+T +C + +G C +C +
Sbjct: 1069 ---CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVD 1125
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
++ CRC+ GY G Y VDEC+ C + A C + GG+ C+C ++CS
Sbjct: 1126 AGNTHHCRCQAGYTGS-YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCS 1182
Score = 64.5 bits (150), Expect = 1e-09
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHS 380
P VD + C N TC++ Y+C C GF G+ C+ DV+EC +
Sbjct: 1228 PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE--RCEGDVNECLS----NPCDARG 1281
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCVEV-DECEGN-THGCHADAVCTNTPGSYTCRCR 438
CV V + C+C G+T + C V + C+G AV +NT + C+C
Sbjct: 1282 TQNCVQRVNDFHCECRAGHTGR---RCESVINGCKGKPCKNGGTCAVASNTARGFICKCP 1338
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+E G TC + D T GS C + C++ C C
Sbjct: 1339 AGFE--GATCEN-DARTCGSLRCLNGGTCISGPRSPTCLC 1375
Score = 60.1 bits (139), Expect = 2e-08
Identities = 54/218 (24%), Positives = 77/218 (35%), Gaps = 33/218 (15%)
Query: 291 CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-----CDENATCMNLNTK 345
C + P LA C P + + G C+ G + C G + C + C++ K
Sbjct: 10 CLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCK 69
Query: 346 ---------------YTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
Y C C GF G + C +G C T +
Sbjct: 70 NAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLT-----LTE 124
Query: 391 YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
Y C+C G++ K +C + D C N C C SY C C + G TC
Sbjct: 125 YKCRCPPGWSGK---SCQQADPCASNP--CANGGQCLPFEASYICHCPPSFHGP--TCRQ 177
Query: 451 -VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
V+EC + C H C N G +RC C + +C
Sbjct: 178 DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNC 215
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 104 bits (250), Expect = 9e-22
Identities = 59/155 (38%), Positives = 80/155 (51%), Gaps = 18/155 (11%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
CN G +CD N +N K C C G+ G + QDVDEC L + C +C+N
Sbjct: 381 CNEGSNCDTNP----VNGKAICTCPSGYTGPACS-QDVDECS----LGANPCEHAGKCIN 431
Query: 387 VVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+G + CQCL GYT C ++V+EC N C DA C + G + C C GYEG
Sbjct: 432 TLGSFECQCLQGYTGP---RCEIDVNECVSNP--CQNDATCLDQIGEFQCMCMPGYEG-V 485
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ ++ DEC S C H+ RC++ F+CEC T
Sbjct: 486 HCEVNTDEC--ASSPCLHNGRCLDKINEFQCECPT 518
Score = 99.1 bits (236), Expect = 4e-20
Identities = 81/282 (28%), Positives = 114/282 (40%), Gaps = 37/282 (13%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGEITC-RP-VECDRAECKNPVLHPGECCPT--CLR 259
C GT H + +++ C C H C RP V C + C+N G C PT
Sbjct: 189 CRHGGTCHNEVGSYR--CV-CRATHTGPNCERPYVPCSPSPCQNG----GTCRPTGDVTH 241
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
+C +C C +G C CP C PP+ G+ C
Sbjct: 242 ECACLPGFTGQNCEENIDDCPGNNCKNGGA-CVDGVNTYNCP---C-PPEW---TGQYCT 293
Query: 320 FCPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
VD C M ++C TC N + Y C C G+ G+ + +++D+C A HG C
Sbjct: 294 --EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS-ENIDDCASAACFHGATC 350
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP--GSYTCR 436
H V + C+C G T C D C N C+ + C P G C
Sbjct: 351 HDR------VASFYCECPHGRTG---LLCHLNDACISNP--CNEGSNCDTNPVNGKAICT 399
Query: 437 CRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C GY G + VDEC+ G++ C H+ +C+N G F C+C
Sbjct: 400 CPSGYTGPACS-QDVDECSLGANPCEHAGKCINTLGSFECQC 440
Score = 88.2 bits (209), Expect = 8e-17
Identities = 64/214 (29%), Positives = 92/214 (42%), Gaps = 35/214 (16%)
Query: 279 CAECVCHDGNMQC--TRVDPELACPR----LPCDPPQQFSVPGECCKFCPGVDYCNMGHS 332
C C +G +C T CP L CD P SV E GVD +
Sbjct: 1064 CDSSPCKNGG-KCWQTHTQYRCECPSGWTGLYCDVP---SVSCEVAAQRQGVDVARL--- 1116
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C C++ + C+C G+ G C+D VDEC + C + C + +GGY
Sbjct: 1117 CQHGGLCVDAGNTHHCRCQAGYTGS--YCEDLVDECSPSP------CQNGATCTDYLGGY 1168
Query: 392 VCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
C+C+ GY NC E+DEC +H C C + P +Y C C G +G + ++
Sbjct: 1169 SCKCVAGY---HGVNCSEEIDEC--LSHPCQNGGTCLDLPNTYKCSCPRGTQG-VHCEIN 1222
Query: 451 VDEC------TEGSHTCHHSARCVNIDGGFRCEC 478
VD+C S C ++ CV+ GG+ C C
Sbjct: 1223 VDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC 1256
Score = 79.4 bits (187), Expect = 4e-14
Identities = 47/164 (28%), Positives = 72/164 (43%), Gaps = 13/164 (7%)
Query: 333 CDENATCMNL-NTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C TC + + C C GF G +++D+C G++C + CV+ V Y
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCE-ENIDDCP------GNNCKNGGACVDGVNTY 279
Query: 392 VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV 451
C C +T ++ +VDEC+ + C C NT G Y C C +G+ G+ + ++
Sbjct: 280 NCPCPPEWT--GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS-ENI 336
Query: 452 DECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
D+C S C H A C + F CEC L C +S
Sbjct: 337 DDCA--SAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Score = 79.4 bits (187), Expect = 4e-14
Identities = 75/287 (26%), Positives = 116/287 (40%), Gaps = 32/287 (11%)
Query: 198 CDCQKS-CYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP 255
CD + C SN V+ C+C G + + + EC NP L+ G C
Sbjct: 750 CDINNNECESNPCVNGGTCKDMTSGIVCTCREG-FSGPNCQTNINECASNPCLNKGTCID 808
Query: 256 TCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
CLL AP CA C +G +C + + + C P
Sbjct: 809 DVAGYKCNCLLPYTGATCEVVLAP--CAPSPCRNGG-ECRQSEDYES---FSCVCPTA-G 861
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAG 371
G+ C+ ++ C + C A+C N + Y C C G+ G C+ D+D+C+
Sbjct: 862 AKGQTCEV--DINECVLS-PCRHGASCQNTHGXYRCHCQAGYSGRN--CETDIDDCRP-- 914
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+ CH+ C + + C CL G+ + F +++EC + C A CT+
Sbjct: 915 ----NPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVD 966
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SYTC C G+ G + + +CTE S C + CV+ F C C
Sbjct: 967 SYTCTCPAGFSGI-HCENNTPDCTESS--CFNGGTCVDGINSFTCLC 1010
Score = 76.6 bits (180), Expect = 3e-13
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 19/176 (10%)
Query: 314 PGECCKFC-PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGG 372
PG C +D C G+ C TC + +TC+C +G+ D +V+EC
Sbjct: 668 PGYTGSMCNSNIDEC-AGNPCHNGGTCEDGINGFTCRCPEGYH-DPTCLSEVNECNSNPC 725
Query: 373 LHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPG 431
+HG C + + GY C C G++ NC + +ECE N C C +
Sbjct: 726 VHG-------ACRDSLNGYKCDCDPGWSGT---NCDINNNECESNP--CVNGGTCKDMTS 773
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
C CR+G+ G +++EC S+ C + C++ G++C C +C
Sbjct: 774 GIVCTCREGFSGPNCQT-NINECA--SNPCLNKGTCIDDVAGYKCNCLLPYTGATC 826
Score = 75.8 bits (178), Expect = 5e-13
Identities = 47/156 (30%), Positives = 77/156 (49%), Gaps = 18/156 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNT 382
V+ C + + C +ATC++ ++ C C G++G + C+ + DEC + LH N
Sbjct: 453 VNEC-VSNPCQNDATCLDQIGEFQCMCMPGYEG--VHCEVNTDECASSPCLH------NG 503
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
RC++ + + C+C G+T +VDEC C A C + P +YTC C +GY
Sbjct: 504 RCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKNGAKCLDGPNTYTCVCTEGYT 559
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + + +DEC CH+ + C + F C C
Sbjct: 560 GT-HCEVDIDEC--DPDPCHYGS-CKDGVATFTCLC 591
Score = 75.4 bits (177), Expect = 6e-13
Identities = 49/162 (30%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGG--LHGHHCHS 380
+D C + H C TC++L Y C C +G Q G+ C+ +VD+C C +
Sbjct: 1185 IDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQ--GVHCEINVDDCNPPVDPVSRSPKCFN 1241
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
N CV+ VGGY C C G+ + C +V+EC N C + C CR
Sbjct: 1242 NGTCVDQVGGYSCTCPPGFVGE---RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1298
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCV---NIDGGFRCEC 478
G+ G C V +G C + C N GF C+C
Sbjct: 1299 GH--TGRRCESVINGCKGK-PCKNGGTCAVASNTARGFICKC 1337
Score = 73.7 bits (173), Expect = 2e-12
Identities = 75/294 (25%), Positives = 113/294 (38%), Gaps = 35/294 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNP 246
G + + + +C + NG DG + C C G T E D EC
Sbjct: 519 GFTGHLCQYDVDECASTPCKNGAKCLDGP----NTYTCVCTEG-YTGTHCEVDIDECDPD 573
Query: 247 VLHPGECCP-TCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPC 305
H G C CL H EC+ C ++ T DP+ A C
Sbjct: 574 PCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCR---LRGTCQDPDNA---YLC 627
Query: 306 DPPQQFSVPGECCKFCP-GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDV 364
F + G C +D C CD + TC++ Y C C G+ G + ++
Sbjct: 628 -----FCLKGTTGPNCEINLDDC-ASSPCD-SGTCLDKIDGYECACEPGYTGS-MCNSNI 679
Query: 365 DECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADA 424
DEC G+ CH+ C + + G+ C+C GY D EV+EC N++ C
Sbjct: 680 DECA------GNPCHNGGTCEDGINGFTCRCPEGY--HDPTCLSEVNEC--NSNPC-VHG 728
Query: 425 VCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C ++ Y C C G+ G ++ +EC S+ C + C ++ G C C
Sbjct: 729 ACRDSLNGYKCDCDPGWSGTNCD-INNNECE--SNPCVNGGTCKDMTSGIVCTC 779
Score = 66.1 bits (154), Expect = 4e-10
Identities = 77/300 (25%), Positives = 113/300 (37%), Gaps = 38/300 (12%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCL 258
DC+ + NG DG + C C+ G E D EC + G C C+
Sbjct: 911 DCRPNPCHNGGSCTDGI----NTAFCDCLPG-FRGTFCEEDINECASDPCRNGANCTDCV 965
Query: 259 RQ--CLLWGNLYE-HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPG 315
C H E P +C E C +G T VD C P F+ G
Sbjct: 966 DSYTCTCPAGFSGIHCENNTP-DCTESSCFNGG---TCVD---GINSFTCLCPPGFT--G 1016
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
C+ V+ C+ C TC + + C C QG+ G CQ+ V C +
Sbjct: 1017 SYCQHV--VNECD-SRPCLLGGTCQDGRGLHRCTCPQGYTGPN--CQNLVHWCDSSP--- 1068
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRK----DKFNCVEVDECEGNTHG--CHADAVCTN 428
C + +C Y C+C G+T +C + +G C +C +
Sbjct: 1069 ---CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVD 1125
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
++ CRC+ GY G Y VDEC+ C + A C + GG+ C+C ++CS
Sbjct: 1126 AGNTHHCRCQAGYTGS-YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCS 1182
Score = 64.5 bits (150), Expect = 1e-09
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHS 380
P VD + C N TC++ Y+C C GF G+ C+ DV+EC +
Sbjct: 1228 PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE--RCEGDVNECLS----NPCDARG 1281
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCVEV-DECEGN-THGCHADAVCTNTPGSYTCRCR 438
CV V + C+C G+T + C V + C+G AV +NT + C+C
Sbjct: 1282 TQNCVQRVNDFHCECRAGHTGR---RCESVINGCKGKPCKNGGTCAVASNTARGFICKCP 1338
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+E G TC + D T GS C + C++ C C
Sbjct: 1339 AGFE--GATCEN-DARTCGSLRCLNGGTCISGPRSPTCLC 1375
Score = 60.1 bits (139), Expect = 2e-08
Identities = 54/218 (24%), Positives = 77/218 (35%), Gaps = 33/218 (15%)
Query: 291 CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-----CDENATCMNLNTK 345
C + P LA C P + + G C+ G + C G + C + C++ K
Sbjct: 10 CLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCK 69
Query: 346 ---------------YTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
Y C C GF G + C +G C T +
Sbjct: 70 NAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLT-----LTE 124
Query: 391 YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
Y C+C G++ K +C + D C N C C SY C C + G TC
Sbjct: 125 YKCRCPPGWSGK---SCQQADPCASNP--CANGGQCLPFEASYICHCPPSFHGP--TCRQ 177
Query: 451 -VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
V+EC + C H C N G +RC C + +C
Sbjct: 178 DVNECGQKPRLCRHGGTCHNEVGSYRCVCRATHTGPNC 215
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 104 bits (249), Expect = 1e-21
Identities = 84/283 (29%), Positives = 132/283 (46%), Gaps = 32/283 (11%)
Query: 213 DGATWQR---DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYE 269
+G+T +R DC C +G + V + C+ P G+ C + +CLL N +
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310
Query: 270 HGERFAPKECAE-CVCHDG--NMQCTRVDPELA---C-PRLPC-DPPQQFSV---PGECC 318
+G A + CVC +G C+ + A C P C D FS G+
Sbjct: 311 NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370
Query: 319 KFCPGVDYCNMGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
C D C + + C + A C LN +Y C C QG++G T +DVDEC A + +
Sbjct: 371 LLCHLDDAC-ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT-EDVDECAMA---NSN 425
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTC 435
C +CVN G + C+CL GY C ++++EC + C DA C + G +TC
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYAGP---RCEMDINECHSDP--CQNDATCLDKIGGFTC 480
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++G + + ++EC S+ C ++ +CV+ F+C C
Sbjct: 481 LCMPGFKG-VHCELEINECQ--SNPCVNNGQCVDKVNRFQCLC 520
Score = 88.6 bits (210), Expect = 6e-17
Identities = 54/154 (35%), Positives = 72/154 (46%), Gaps = 20/154 (12%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ + C TC NL Y C C +GF+ G CQ ++DEC + C + C +
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECA------SNPCLNQGTCFDD 813
Query: 388 VGGYVCQCLGGYTRKDKFNCVEV-DECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGD 444
+ GY C C+ YT K NC V C N C AVC +P SYTC C G++G
Sbjct: 814 ISGYTCHCVLPYTGK---NCQTVLAPCSPNP--CENAAVCKESPNFESYTCLCAPGWQGQ 868
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T + +DEC S C + C N G + CEC
Sbjct: 869 RCT-IDIDECI--SKPCMNHGLCHNTQGSYMCEC 899
Score = 87.0 bits (206), Expect = 2e-16
Identities = 80/297 (26%), Positives = 113/297 (38%), Gaps = 37/297 (12%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRCSCVH----GEITCRPVECDRAE-CKNPVLHPGE 252
C C + H D R N +CV G+ TCR E C+ HP
Sbjct: 51 CKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCF 110
Query: 253 CCPTCLR--QC-LLWGNLYEHGER--FAPKECA---ECVCHD--GNMQCTRVDPELACPR 302
CL C +L + YE + F KEC C+ H CT V + +C
Sbjct: 111 VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
L G+ C+ V+ C++ C TC+NL Y C+C QGF G
Sbjct: 171 LT-------GFTGQKCE--TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL 221
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCH 421
V C + ++G C + C CL G+ + C +D+C H C
Sbjct: 222 YV-PCAPSPCVNGGTCRQTGDFT-----FECNCLPGF---EGSTCERNIDDCP--NHRCQ 270
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC + +Y CRC + G + VDEC + C + C N +GG+ C C
Sbjct: 271 NGGVCVDGVNTYNCRCPPQWTGQ-FCTEDVDECLLQPNACQNGGTCANRNGGYGCVC 326
Score = 83.4 bits (197), Expect = 2e-15
Identities = 71/260 (27%), Positives = 108/260 (41%), Gaps = 33/260 (12%)
Query: 243 CKNPVLHPGECCPTCLRQCLLWG-NLYEHGERFAPKECA-ECVCHDGNMQCTRVDPEL-A 299
C P + G C + +C + N EH + + A C C G R + ++
Sbjct: 401 CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG-PRCEMDINE 459
Query: 300 CPRLPC--DPPQQFSVPGECCKFCPGVD--YCNM------GHSCDENATCMNLNTKYTCK 349
C PC D + G C PG +C + + C N C++ ++ C
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
Query: 350 CNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C GF G CQ D+D+C L+G +C++ GY CQC G+T C
Sbjct: 520 CPPGFTGP--VCQIDIDDCSSTPCLNG------AKCIDHPNGYECQCATGFT---GVLCE 568
Query: 409 E-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
E +D C+ + CH C + SYTC C GY G +DEC S C + RC
Sbjct: 569 ENIDNCDPDP--CH-HGQCQDGIDSYTCICNPGYMG-AICSDQIDECY--SSPCLNDGRC 622
Query: 468 VNIDGGFRCECFTENCELSC 487
+++ G++C C ++C
Sbjct: 623 IDLVNGYQCNCQPGTSGVNC 642
Score = 79.8 bits (188), Expect = 3e-14
Identities = 74/261 (28%), Positives = 112/261 (42%), Gaps = 38/261 (14%)
Query: 224 CSCVHGEITCRPVECDRA--ECK-NPVLHPGECCPTCLR-QCLLWGNLYEHGERFAPKEC 279
C C+ G + V C+ EC+ NP ++ G+C R QCL + +C
Sbjct: 480 CLCMPG---FKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC 536
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC 339
+ C +G +C +D C F+ G C+ +D C+ C + C
Sbjct: 537 SSTPCLNG-AKC--IDHPNG---YECQCATGFT--GVLCE--ENIDNCDPD-PC-HHGQC 584
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ YTC CN G+ G C D +DEC + C ++ RC+++V GY C C G
Sbjct: 585 QDGIDSYTCICNPGYMG--AICSDQIDEC------YSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 399 YTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEG 457
+ NC + D+C N C +C + Y+C C G+ G + +DEC
Sbjct: 637 TSG---VNCEINFDDCASNP--C-IHGICMDGINRYSCVCSPGFTGQRCN-IDIDEC--A 687
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S+ C A C+N GFRC C
Sbjct: 688 SNPCRKGATCINGVNGFRCIC 708
Score = 78.2 bits (184), Expect = 9e-14
Identities = 63/211 (29%), Positives = 88/211 (41%), Gaps = 24/211 (11%)
Query: 274 FAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSC 333
F E EC H + T VD L R C P ++ G+ C+ V+ C+ C
Sbjct: 1021 FCLHEINECSSHPCLNEGTCVDG-LGTYRCSC--PLGYT--GKNCQTL--VNLCSRS-PC 1072
Query: 334 DENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHG----HHCHSNTRCVNVVG 389
TC+ + C C G+ G +V C A G H C + C+N
Sbjct: 1073 KNKGTCVQKKAESQCLCPSGWAGAYCDVPNVS-CDIAASRRGVLVEHLCQHSGVCINAGN 1131
Query: 390 GYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC 448
+ CQC GYT C E +DEC N C A C++ G Y C C GY+G C
Sbjct: 1132 THYCQCPLGYTGS---YCEEQLDECASNP--CQHGATCSDFIGGYRCECVPGYQG--VNC 1184
Query: 449 MH-VDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ VDEC + C + C+++ F+C C
Sbjct: 1185 EYEVDECQ--NQPCQNGGTCIDLVNHFKCSC 1213
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/156 (30%), Positives = 71/156 (45%), Gaps = 18/156 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + C + ATC+N + C C +G Q V+EC +HG+
Sbjct: 683 IDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-VNECLSNPCIHGN------- 733
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C + GY C C G+ NC EVD+ E ++ C C N Y C C+ G++
Sbjct: 734 CTGGLSGYKCLCDAGWVG---INC-EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK- 788
Query: 444 DGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY C +++DEC S+ C + C + G+ C C
Sbjct: 789 -GYNCQVNIDEC--ASNPCLNQGTCFDDISGYTCHC 821
Score = 72.1 bits (169), Expect = 6e-12
Identities = 83/305 (27%), Positives = 112/305 (36%), Gaps = 44/305 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP-- 255
DC + NG DG + C C+ G T + D EC P + G C
Sbjct: 914 DCLANPCQNGGSCMDGV----NTFSCLCLPG-FTGDKYQTDMNECLSEPCKNGGTCSDYV 968
Query: 256 ---TCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
TC Q G E+ EC E C +G T VD C P F+
Sbjct: 969 NSYTCKCQAGFDGVHCENNIN----ECTESSCFNGG---TCVD---GINSFSCLCPVGFT 1018
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAG 371
G C ++ C+ H C TC++ Y C C G+ G CQ V+ C +
Sbjct: 1019 --GSFCLH--EINECS-SHPCLNEGTCVDGLGTYRCSCPLGYTGKN--CQTLVNLCSRSP 1071
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQC----LGGYTRKDKFNCVEVDECEGNT--HGCHADAV 425
C + CV C C G Y +C G H C V
Sbjct: 1072 ------CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCEL 485
C N ++ C+C GY G Y +DEC S+ C H A C + GG+RCEC +
Sbjct: 1126 CINAGNTHYCQCPLGYTGS-YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGV 1182
Query: 486 SCSWQ 490
+C ++
Sbjct: 1183 NCEYE 1187
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/177 (27%), Positives = 73/177 (41%), Gaps = 35/177 (19%)
Query: 317 CCKFCPGVDYCNMGHS-CDENATCMNLN--TKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
CC C G+ C C+ + T Y CKC +GF G+ CQ D C++
Sbjct: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGY-CKCPEGFLGE--YCQHRDPCEK---- 70
Query: 374 HGHHCHSNTRCVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNT-HGCHADAVCTN-- 428
+ C + CV ++G C+C G+T +D C+ +T H C C N
Sbjct: 71 --NRCQNGGTCVAQAMLGKATCRCASGFTGED---------CQYSTSHPCFVSRPCLNGG 119
Query: 429 -----TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ +Y C C+ G+ G C D C SH C + + C + F C+C T
Sbjct: 120 TCHMLSRDTYECTCQVGFTGK--ECQWTDACL--SHPCANGSTCTTVANQFSCKCLT 172
Score = 56.0 bits (129), Expect = 4e-07
Identities = 78/301 (25%), Positives = 107/301 (35%), Gaps = 44/301 (14%)
Query: 200 CQKSCYSNGTVHADGATWQR---DCNRCS---CVHGEITCRPVECDRAECKNPVLHPGEC 253
C V + G T QR D + C+ C G V R C HP
Sbjct: 659 CMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS-- 716
Query: 254 CPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQF 311
C + + +CL N HG +C+C G + C VD C PC
Sbjct: 717 CYSQVNECL--SNPCIHGNCTGGLSGYKCLCDAGWVGINC-EVDKN-ECLSNPCQNGGTC 772
Query: 312 S--VPGECCKFCPGVDYCNMGHSCDENAT--CMNLNT------KYTCKCNQGFQGDGLTC 361
V G C G N + DE A+ C+N T YTC C + G C
Sbjct: 773 DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN--C 830
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVG--GYVCQCLGGYTRKDKFNC-VEVDECEGNTH 418
Q V + C + C Y C C G+ + C +++DEC
Sbjct: 831 QTV-----LAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKP- 881
Query: 419 GCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCE 477
C +C NT GSY C C G+ G C +D+C ++ C + C++ F C
Sbjct: 882 -CMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCL 936
Query: 478 C 478
C
Sbjct: 937 C 937
Score = 45.2 bits (102), Expect = 7e-04
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 10/76 (13%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNT 382
+D C + C ATC + Y C+C G+QG + C+ +VDECQ C +
Sbjct: 1150 LDEC-ASNPCQHGATCSDFIGGYRCECVPGYQG--VNCEYEVDECQN------QPCQNGG 1200
Query: 383 RCVNVVGGYVCQCLGG 398
C+++V + C C G
Sbjct: 1201 TCIDLVNHFKCSCPPG 1216
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 104 bits (249), Expect = 1e-21
Identities = 84/283 (29%), Positives = 132/283 (46%), Gaps = 32/283 (11%)
Query: 213 DGATWQR---DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYE 269
+G+T +R DC C +G + V + C+ P G+ C + +CLL N +
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310
Query: 270 HGERFAPKECAE-CVCHDG--NMQCTRVDPELA---C-PRLPC-DPPQQFSV---PGECC 318
+G A + CVC +G C+ + A C P C D FS G+
Sbjct: 311 NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370
Query: 319 KFCPGVDYCNMGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
C D C + + C + A C LN +Y C C QG++G T +DVDEC A + +
Sbjct: 371 LLCHLDDAC-ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT-EDVDECAMA---NSN 425
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTC 435
C +CVN G + C+CL GY C ++++EC + C DA C + G +TC
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYAGP---RCEMDINECHSDP--CQNDATCLDKIGGFTC 480
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++G + + ++EC S+ C ++ +CV+ F+C C
Sbjct: 481 LCMPGFKG-VHCELEINECQ--SNPCVNNGQCVDKVNRFQCLC 520
Score = 88.6 bits (210), Expect = 6e-17
Identities = 54/154 (35%), Positives = 72/154 (46%), Gaps = 20/154 (12%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ + C TC NL Y C C +GF+ G CQ ++DEC + C + C +
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECA------SNPCLNQGTCFDD 813
Query: 388 VGGYVCQCLGGYTRKDKFNCVEV-DECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGD 444
+ GY C C+ YT K NC V C N C AVC +P SYTC C G++G
Sbjct: 814 ISGYTCHCVLPYTGK---NCQTVLAPCSPNP--CENAAVCKESPNFESYTCLCAPGWQGQ 868
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T + +DEC S C + C N G + CEC
Sbjct: 869 RCT-IDIDECI--SKPCMNHGLCHNTQGSYMCEC 899
Score = 87.0 bits (206), Expect = 2e-16
Identities = 80/297 (26%), Positives = 113/297 (38%), Gaps = 37/297 (12%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRCSCVH----GEITCRPVECDRAE-CKNPVLHPGE 252
C C + H D R N +CV G+ TCR E C+ HP
Sbjct: 51 CKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCF 110
Query: 253 CCPTCLR--QC-LLWGNLYEHGER--FAPKECA---ECVCHD--GNMQCTRVDPELACPR 302
CL C +L + YE + F KEC C+ H CT V + +C
Sbjct: 111 VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
L G+ C+ V+ C++ C TC+NL Y C+C QGF G
Sbjct: 171 LT-------GFTGQKCE--TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL 221
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCH 421
V C + ++G C + C CL G+ + C +D+C H C
Sbjct: 222 YV-PCAPSPCVNGGTCRQTGDFT-----FECNCLPGF---EGSTCERNIDDCP--NHRCQ 270
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC + +Y CRC + G + VDEC + C + C N +GG+ C C
Sbjct: 271 NGGVCVDGVNTYNCRCPPQWTGQ-FCTEDVDECLLQPNACQNGGTCANRNGGYGCVC 326
Score = 83.4 bits (197), Expect = 2e-15
Identities = 71/260 (27%), Positives = 108/260 (41%), Gaps = 33/260 (12%)
Query: 243 CKNPVLHPGECCPTCLRQCLLWG-NLYEHGERFAPKECA-ECVCHDGNMQCTRVDPEL-A 299
C P + G C + +C + N EH + + A C C G R + ++
Sbjct: 401 CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG-PRCEMDINE 459
Query: 300 CPRLPC--DPPQQFSVPGECCKFCPGVD--YCNM------GHSCDENATCMNLNTKYTCK 349
C PC D + G C PG +C + + C N C++ ++ C
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
Query: 350 CNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C GF G CQ D+D+C L+G +C++ GY CQC G+T C
Sbjct: 520 CPPGFTGP--VCQIDIDDCSSTPCLNG------AKCIDHPNGYECQCATGFT---GVLCE 568
Query: 409 E-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
E +D C+ + CH C + SYTC C GY G +DEC S C + RC
Sbjct: 569 ENIDNCDPDP--CH-HGQCQDGIDSYTCICNPGYMG-AICSDQIDECY--SSPCLNDGRC 622
Query: 468 VNIDGGFRCECFTENCELSC 487
+++ G++C C ++C
Sbjct: 623 IDLVNGYQCNCQPGTSGVNC 642
Score = 79.8 bits (188), Expect = 3e-14
Identities = 74/261 (28%), Positives = 112/261 (42%), Gaps = 38/261 (14%)
Query: 224 CSCVHGEITCRPVECDRA--ECK-NPVLHPGECCPTCLR-QCLLWGNLYEHGERFAPKEC 279
C C+ G + V C+ EC+ NP ++ G+C R QCL + +C
Sbjct: 480 CLCMPG---FKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC 536
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC 339
+ C +G +C +D C F+ G C+ +D C+ C + C
Sbjct: 537 SSTPCLNG-AKC--IDHPNG---YECQCATGFT--GVLCE--ENIDNCDPD-PC-HHGQC 584
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ YTC CN G+ G C D +DEC + C ++ RC+++V GY C C G
Sbjct: 585 QDGIDSYTCICNPGYMG--AICSDQIDEC------YSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 399 YTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEG 457
+ NC + D+C N C +C + Y+C C G+ G + +DEC
Sbjct: 637 TSG---VNCEINFDDCASNP--C-IHGICMDGINRYSCVCSPGFTGQRCN-IDIDEC--A 687
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S+ C A C+N GFRC C
Sbjct: 688 SNPCRKGATCINGVNGFRCIC 708
Score = 76.6 bits (180), Expect = 3e-13
Identities = 62/219 (28%), Positives = 91/219 (41%), Gaps = 33/219 (15%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
ECA C G C+ C C P Q G C++ VD C C
Sbjct: 1152 ECASNPCQHG-ATCSDFIGGYRCE---CVPGYQ----GVNCEY--EVDECQ-NQPCQNGG 1200
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC++L + C C G +G L C++ +D+C G HC + +C++ +GGY C+CL
Sbjct: 1201 TCIDLVNHFKCSCPPGTRG--LLCEENIDDCAR-----GPHCLNGGQCMDRIGGYSCRCL 1253
Query: 397 GGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G+ + C +++EC N C Y C CR + G + VD C
Sbjct: 1254 PGFAGE---RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG-RHCETFVDVCP 1309
Query: 456 EGSHTCHHSARCV---NIDGGFRCEC---FT-ENCELSC 487
+ C + C N+ GF C C F+ C+ SC
Sbjct: 1310 Q--MPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/156 (30%), Positives = 71/156 (45%), Gaps = 18/156 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + C + ATC+N + C C +G Q V+EC +HG+
Sbjct: 683 IDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-VNECLSNPCIHGN------- 733
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C + GY C C G+ NC EVD+ E ++ C C N Y C C+ G++
Sbjct: 734 CTGGLSGYKCLCDAGWVG---INC-EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK- 788
Query: 444 DGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY C +++DEC S+ C + C + G+ C C
Sbjct: 789 -GYNCQVNIDEC--ASNPCLNQGTCFDDISGYTCHC 821
Score = 72.1 bits (169), Expect = 6e-12
Identities = 83/305 (27%), Positives = 112/305 (36%), Gaps = 44/305 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP-- 255
DC + NG DG + C C+ G T + D EC P + G C
Sbjct: 914 DCLANPCQNGGSCMDGV----NTFSCLCLPG-FTGDKCQTDMNECLSEPCKNGGTCSDYV 968
Query: 256 ---TCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
TC Q G E+ EC E C +G T VD C P F+
Sbjct: 969 NSYTCKCQAGFDGVHCENNIN----ECTESSCFNGG---TCVD---GINSFSCLCPVGFT 1018
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAG 371
G C ++ C+ H C TC++ Y C C G+ G CQ V+ C +
Sbjct: 1019 --GSFCLH--EINECS-SHPCLNEGTCVDGLGTYRCSCPLGYTGKN--CQTLVNLCSRSP 1071
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQC----LGGYTRKDKFNCVEVDECEGNT--HGCHADAV 425
C + CV C C G Y +C G H C V
Sbjct: 1072 ------CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCEL 485
C N ++ C+C GY G Y +DEC S+ C H A C + GG+RCEC +
Sbjct: 1126 CINAGNTHYCQCPLGYTGS-YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGV 1182
Query: 486 SCSWQ 490
+C ++
Sbjct: 1183 NCEYE 1187
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/177 (27%), Positives = 73/177 (41%), Gaps = 35/177 (19%)
Query: 317 CCKFCPGVDYCNMGHS-CDENATCMNLN--TKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
CC C G+ C C+ + T Y CKC +GF G+ CQ D C++
Sbjct: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGY-CKCPEGFLGE--YCQHRDPCEK---- 70
Query: 374 HGHHCHSNTRCVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNT-HGCHADAVCTN-- 428
+ C + CV ++G C+C G+T +D C+ +T H C C N
Sbjct: 71 --NRCQNGGTCVAQAMLGKATCRCASGFTGED---------CQYSTSHPCFVSRPCLNGG 119
Query: 429 -----TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ +Y C C+ G+ G C D C SH C + + C + F C+C T
Sbjct: 120 TCHMLSRDTYECTCQVGFTGK--ECQWTDACL--SHPCANGSTCTTVANQFSCKCLT 172
Score = 56.0 bits (129), Expect = 4e-07
Identities = 78/301 (25%), Positives = 107/301 (35%), Gaps = 44/301 (14%)
Query: 200 CQKSCYSNGTVHADGATWQR---DCNRCS---CVHGEITCRPVECDRAECKNPVLHPGEC 253
C V + G T QR D + C+ C G V R C HP
Sbjct: 659 CMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS-- 716
Query: 254 CPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQF 311
C + + +CL N HG +C+C G + C VD C PC
Sbjct: 717 CYSQVNECL--SNPCIHGNCTGGLSGYKCLCDAGWVGINC-EVDKN-ECLSNPCQNGGTC 772
Query: 312 S--VPGECCKFCPGVDYCNMGHSCDENAT--CMNLNT------KYTCKCNQGFQGDGLTC 361
V G C G N + DE A+ C+N T YTC C + G C
Sbjct: 773 DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN--C 830
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVG--GYVCQCLGGYTRKDKFNC-VEVDECEGNTH 418
Q V + C + C Y C C G+ + C +++DEC
Sbjct: 831 QTV-----LAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKP- 881
Query: 419 GCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCE 477
C +C NT GSY C C G+ G C +D+C ++ C + C++ F C
Sbjct: 882 -CMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCL 936
Query: 478 C 478
C
Sbjct: 937 C 937
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/291 (24%), Positives = 109/291 (37%), Gaps = 42/291 (14%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGE--ITCRPVECDRAECKNPVLHPGECCPTCLRQC 261
C SN H + RC CV G + C E D EC+N G TC+
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCE-YEVD--ECQNQPCQNGG---TCI--- 1203
Query: 262 LLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS---VPGECC 318
+L H + P +C + C R P D +S +PG
Sbjct: 1204 ----DLVNHFKCSCPPGTRGLLCEENIDDCAR-GPHCLNGGQCMDRIGGYSCRCLPGFAG 1258
Query: 319 KFCPG-VDYCNMGHSCDENAT--CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
+ C G ++ C + + C + C+ L Y C C F G C+ VD C + L+
Sbjct: 1259 ERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRH--CETFVDVCPQMPCLN 1315
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C + N+ G++C+C G++ + + +C +V C C +T
Sbjct: 1316 GGTCAVAS---NMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQCVHTASGP 1364
Query: 434 TCRC---RDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
C C RD G + C H C ++S +C G RCE +T
Sbjct: 1365 RCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 104 bits (249), Expect = 1e-21
Identities = 84/283 (29%), Positives = 132/283 (46%), Gaps = 32/283 (11%)
Query: 213 DGATWQR---DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYE 269
+G+T +R DC C +G + V + C+ P G+ C + +CLL N +
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310
Query: 270 HGERFAPKECAE-CVCHDG--NMQCTRVDPELA---C-PRLPC-DPPQQFSV---PGECC 318
+G A + CVC +G C+ + A C P C D FS G+
Sbjct: 311 NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370
Query: 319 KFCPGVDYCNMGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
C D C + + C + A C LN +Y C C QG++G T +DVDEC A + +
Sbjct: 371 LLCHLDDAC-ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT-EDVDECAMA---NSN 425
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTC 435
C +CVN G + C+CL GY C ++++EC + C DA C + G +TC
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYAGP---RCEMDINECHSDP--CQNDATCLDKIGGFTC 480
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++G + + ++EC S+ C ++ +CV+ F+C C
Sbjct: 481 LCMPGFKG-VHCELEINECQ--SNPCVNNGQCVDKVNRFQCLC 520
Score = 88.6 bits (210), Expect = 6e-17
Identities = 54/154 (35%), Positives = 72/154 (46%), Gaps = 20/154 (12%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ + C TC NL Y C C +GF+ G CQ ++DEC + C + C +
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECA------SNPCLNQGTCFDD 813
Query: 388 VGGYVCQCLGGYTRKDKFNCVEV-DECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGD 444
+ GY C C+ YT K NC V C N C AVC +P SYTC C G++G
Sbjct: 814 ISGYTCHCVLPYTGK---NCQTVLAPCSPNP--CENAAVCKESPNFESYTCLCAPGWQGQ 868
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T + +DEC S C + C N G + CEC
Sbjct: 869 RCT-IDIDECI--SKPCMNHGLCHNTQGSYMCEC 899
Score = 87.0 bits (206), Expect = 2e-16
Identities = 80/297 (26%), Positives = 113/297 (38%), Gaps = 37/297 (12%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRCSCVH----GEITCRPVECDRAE-CKNPVLHPGE 252
C C + H D R N +CV G+ TCR E C+ HP
Sbjct: 51 CKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCF 110
Query: 253 CCPTCLR--QC-LLWGNLYEHGER--FAPKECA---ECVCHD--GNMQCTRVDPELACPR 302
CL C +L + YE + F KEC C+ H CT V + +C
Sbjct: 111 VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
L G+ C+ V+ C++ C TC+NL Y C+C QGF G
Sbjct: 171 LT-------GFTGQKCE--TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL 221
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCH 421
V C + ++G C + C CL G+ + C +D+C H C
Sbjct: 222 YV-PCAPSPCVNGGTCRQTGDFT-----FECNCLPGF---EGSTCERNIDDCP--NHRCQ 270
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC + +Y CRC + G + VDEC + C + C N +GG+ C C
Sbjct: 271 NGGVCVDGVNTYNCRCPPQWTGQ-FCTEDVDECLLQPNACQNGGTCANRNGGYGCVC 326
Score = 83.4 bits (197), Expect = 2e-15
Identities = 71/260 (27%), Positives = 108/260 (41%), Gaps = 33/260 (12%)
Query: 243 CKNPVLHPGECCPTCLRQCLLWG-NLYEHGERFAPKECA-ECVCHDGNMQCTRVDPEL-A 299
C P + G C + +C + N EH + + A C C G R + ++
Sbjct: 401 CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG-PRCEMDINE 459
Query: 300 CPRLPC--DPPQQFSVPGECCKFCPGVD--YCNM------GHSCDENATCMNLNTKYTCK 349
C PC D + G C PG +C + + C N C++ ++ C
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
Query: 350 CNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C GF G CQ D+D+C L+G +C++ GY CQC G+T C
Sbjct: 520 CPPGFTGP--VCQIDIDDCSSTPCLNG------AKCIDHPNGYECQCATGFT---GVLCE 568
Query: 409 E-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
E +D C+ + CH C + SYTC C GY G +DEC S C + RC
Sbjct: 569 ENIDNCDPDP--CH-HGQCQDGIDSYTCICNPGYMG-AICSDQIDECY--SSPCLNDGRC 622
Query: 468 VNIDGGFRCECFTENCELSC 487
+++ G++C C ++C
Sbjct: 623 IDLVNGYQCNCQPGTSGVNC 642
Score = 79.8 bits (188), Expect = 3e-14
Identities = 74/261 (28%), Positives = 112/261 (42%), Gaps = 38/261 (14%)
Query: 224 CSCVHGEITCRPVECDRA--ECK-NPVLHPGECCPTCLR-QCLLWGNLYEHGERFAPKEC 279
C C+ G + V C+ EC+ NP ++ G+C R QCL + +C
Sbjct: 480 CLCMPG---FKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC 536
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC 339
+ C +G +C +D C F+ G C+ +D C+ C + C
Sbjct: 537 SSTPCLNG-AKC--IDHPNG---YECQCATGFT--GVLCE--ENIDNCDPD-PC-HHGQC 584
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ YTC CN G+ G C D +DEC + C ++ RC+++V GY C C G
Sbjct: 585 QDGIDSYTCICNPGYMG--AICSDQIDEC------YSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 399 YTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEG 457
+ NC + D+C N C +C + Y+C C G+ G + +DEC
Sbjct: 637 TSG---VNCEINFDDCASNP--C-IHGICMDGINRYSCVCSPGFTGQRCN-IDIDEC--A 687
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S+ C A C+N GFRC C
Sbjct: 688 SNPCRKGATCINGVNGFRCIC 708
Score = 76.6 bits (180), Expect = 3e-13
Identities = 62/219 (28%), Positives = 91/219 (41%), Gaps = 33/219 (15%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
ECA C G C+ C C P Q G C++ VD C C
Sbjct: 1152 ECASNPCQHG-ATCSDFIGGYRCE---CVPGYQ----GVNCEY--EVDECQ-NQPCQNGG 1200
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC++L + C C G +G L C++ +D+C G HC + +C++ +GGY C+CL
Sbjct: 1201 TCIDLVNHFKCSCPPGTRG--LLCEENIDDCAR-----GPHCLNGGQCMDRIGGYSCRCL 1253
Query: 397 GGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G+ + C +++EC N C Y C CR + G + VD C
Sbjct: 1254 PGFAGE---RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG-RHCETFVDVCP 1309
Query: 456 EGSHTCHHSARCV---NIDGGFRCEC---FT-ENCELSC 487
+ C + C N+ GF C C F+ C+ SC
Sbjct: 1310 Q--MPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/156 (30%), Positives = 71/156 (45%), Gaps = 18/156 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + C + ATC+N + C C +G Q V+EC +HG+
Sbjct: 683 IDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-VNECLSNPCIHGN------- 733
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C + GY C C G+ NC EVD+ E ++ C C N Y C C+ G++
Sbjct: 734 CTGGLSGYKCLCDAGWVG---INC-EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK- 788
Query: 444 DGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY C +++DEC S+ C + C + G+ C C
Sbjct: 789 -GYNCQVNIDEC--ASNPCLNQGTCFDDISGYTCHC 821
Score = 72.1 bits (169), Expect = 6e-12
Identities = 83/305 (27%), Positives = 112/305 (36%), Gaps = 44/305 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP-- 255
DC + NG DG + C C+ G T + D EC P + G C
Sbjct: 914 DCLANPCQNGGSCMDGV----NTFSCLCLPG-FTGDKCQTDMNECLSEPCKNGGTCSDYV 968
Query: 256 ---TCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
TC Q G E+ EC E C +G T VD C P F+
Sbjct: 969 NSYTCKCQAGFDGVHCENNIN----ECTESSCFNGG---TCVD---GINSFSCLCPVGFT 1018
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAG 371
G C ++ C+ H C TC++ Y C C G+ G CQ V+ C +
Sbjct: 1019 --GSFCLH--EINECS-SHPCLNEGTCVDGLGTYRCSCPLGYTGKN--CQTLVNLCSRSP 1071
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQC----LGGYTRKDKFNCVEVDECEGNT--HGCHADAV 425
C + CV C C G Y +C G H C V
Sbjct: 1072 ------CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCEL 485
C N ++ C+C GY G Y +DEC S+ C H A C + GG+RCEC +
Sbjct: 1126 CINAGNTHYCQCPLGYTGS-YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGV 1182
Query: 486 SCSWQ 490
+C ++
Sbjct: 1183 NCEYE 1187
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/177 (27%), Positives = 73/177 (41%), Gaps = 35/177 (19%)
Query: 317 CCKFCPGVDYCNMGHS-CDENATCMNLN--TKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
CC C G+ C C+ + T Y CKC +GF G+ CQ D C++
Sbjct: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGY-CKCPEGFLGE--YCQHRDPCEK---- 70
Query: 374 HGHHCHSNTRCVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNT-HGCHADAVCTN-- 428
+ C + CV ++G C+C G+T +D C+ +T H C C N
Sbjct: 71 --NRCQNGGTCVAQAMLGKATCRCASGFTGED---------CQYSTSHPCFVSRPCLNGG 119
Query: 429 -----TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ +Y C C+ G+ G C D C SH C + + C + F C+C T
Sbjct: 120 TCHMLSRDTYECTCQVGFTGK--ECQWTDACL--SHPCANGSTCTTVANQFSCKCLT 172
Score = 56.0 bits (129), Expect = 4e-07
Identities = 78/301 (25%), Positives = 107/301 (35%), Gaps = 44/301 (14%)
Query: 200 CQKSCYSNGTVHADGATWQR---DCNRCS---CVHGEITCRPVECDRAECKNPVLHPGEC 253
C V + G T QR D + C+ C G V R C HP
Sbjct: 659 CMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS-- 716
Query: 254 CPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQF 311
C + + +CL N HG +C+C G + C VD C PC
Sbjct: 717 CYSQVNECL--SNPCIHGNCTGGLSGYKCLCDAGWVGINC-EVDKN-ECLSNPCQNGGTC 772
Query: 312 S--VPGECCKFCPGVDYCNMGHSCDENAT--CMNLNT------KYTCKCNQGFQGDGLTC 361
V G C G N + DE A+ C+N T YTC C + G C
Sbjct: 773 DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN--C 830
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVG--GYVCQCLGGYTRKDKFNC-VEVDECEGNTH 418
Q V + C + C Y C C G+ + C +++DEC
Sbjct: 831 QTV-----LAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKP- 881
Query: 419 GCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCE 477
C +C NT GSY C C G+ G C +D+C ++ C + C++ F C
Sbjct: 882 -CMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCL 936
Query: 478 C 478
C
Sbjct: 937 C 937
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/291 (24%), Positives = 109/291 (37%), Gaps = 42/291 (14%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGE--ITCRPVECDRAECKNPVLHPGECCPTCLRQC 261
C SN H + RC CV G + C E D EC+N G TC+
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCE-YEVD--ECQNQPCQNGG---TCI--- 1203
Query: 262 LLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS---VPGECC 318
+L H + P +C + C R P D +S +PG
Sbjct: 1204 ----DLVNHFKCSCPPGTRGLLCEENIDDCAR-GPHCLNGGQCMDRIGGYSCRCLPGFAG 1258
Query: 319 KFCPG-VDYCNMGHSCDENAT--CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
+ C G ++ C + + C + C+ L Y C C F G C+ VD C + L+
Sbjct: 1259 ERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRH--CETFVDVCPQMPCLN 1315
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C + N+ G++C+C G++ + + +C +V C C +T
Sbjct: 1316 GGTCAVAS---NMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQCVHTASGP 1364
Query: 434 TCRC---RDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
C C RD G + C H C ++S +C G RCE +T
Sbjct: 1365 RCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2
(Drosophila) protein.
Length = 2471
Score = 104 bits (249), Expect = 1e-21
Identities = 84/283 (29%), Positives = 132/283 (46%), Gaps = 32/283 (11%)
Query: 213 DGATWQR---DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYE 269
+G+T +R DC C +G + V + C+ P G+ C + +CLL N +
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310
Query: 270 HGERFAPKECAE-CVCHDG--NMQCTRVDPELA---C-PRLPC-DPPQQFSV---PGECC 318
+G A + CVC +G C+ + A C P C D FS G+
Sbjct: 311 NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370
Query: 319 KFCPGVDYCNMGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
C D C + + C + A C LN +Y C C QG++G T +DVDEC A + +
Sbjct: 371 LLCHLDDAC-ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT-EDVDECAMA---NSN 425
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTC 435
C +CVN G + C+CL GY C ++++EC + C DA C + G +TC
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYAGP---RCEMDINECHSDP--CQNDATCLDKIGGFTC 480
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++G + + ++EC S+ C ++ +CV+ F+C C
Sbjct: 481 LCMPGFKG-VHCELEINECQ--SNPCVNNGQCVDKVNRFQCLC 520
Score = 88.6 bits (210), Expect = 6e-17
Identities = 54/154 (35%), Positives = 72/154 (46%), Gaps = 20/154 (12%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ + C TC NL Y C C +GF+ G CQ ++DEC + C + C +
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECA------SNPCLNQGTCFDD 813
Query: 388 VGGYVCQCLGGYTRKDKFNCVEV-DECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGD 444
+ GY C C+ YT K NC V C N C AVC +P SYTC C G++G
Sbjct: 814 ISGYTCHCVLPYTGK---NCQTVLAPCSPNP--CENAAVCKESPNFESYTCLCAPGWQGQ 868
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T + +DEC S C + C N G + CEC
Sbjct: 869 RCT-IDIDECI--SKPCMNHGLCHNTQGSYMCEC 899
Score = 87.0 bits (206), Expect = 2e-16
Identities = 80/297 (26%), Positives = 113/297 (38%), Gaps = 37/297 (12%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRCSCVH----GEITCRPVECDRAE-CKNPVLHPGE 252
C C + H D R N +CV G+ TCR E C+ HP
Sbjct: 51 CKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCF 110
Query: 253 CCPTCLR--QC-LLWGNLYEHGER--FAPKECA---ECVCHD--GNMQCTRVDPELACPR 302
CL C +L + YE + F KEC C+ H CT V + +C
Sbjct: 111 VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
L G+ C+ V+ C++ C TC+NL Y C+C QGF G
Sbjct: 171 LT-------GFTGQKCE--TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL 221
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCH 421
V C + ++G C + C CL G+ + C +D+C H C
Sbjct: 222 YV-PCAPSPCVNGGTCRQTGDFT-----FECNCLPGF---EGSTCERNIDDCP--NHRCQ 270
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC + +Y CRC + G + VDEC + C + C N +GG+ C C
Sbjct: 271 NGGVCVDGVNTYNCRCPPQWTGQ-FCTEDVDECLLQPNACQNGGTCANRNGGYGCVC 326
Score = 83.4 bits (197), Expect = 2e-15
Identities = 71/260 (27%), Positives = 108/260 (41%), Gaps = 33/260 (12%)
Query: 243 CKNPVLHPGECCPTCLRQCLLWG-NLYEHGERFAPKECA-ECVCHDGNMQCTRVDPEL-A 299
C P + G C + +C + N EH + + A C C G R + ++
Sbjct: 401 CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG-PRCEMDINE 459
Query: 300 CPRLPC--DPPQQFSVPGECCKFCPGVD--YCNM------GHSCDENATCMNLNTKYTCK 349
C PC D + G C PG +C + + C N C++ ++ C
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
Query: 350 CNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C GF G CQ D+D+C L+G +C++ GY CQC G+T C
Sbjct: 520 CPPGFTGP--VCQIDIDDCSSTPCLNG------AKCIDHPNGYECQCATGFT---GVLCE 568
Query: 409 E-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
E +D C+ + CH C + SYTC C GY G +DEC S C + RC
Sbjct: 569 ENIDNCDPDP--CH-HGQCQDGIDSYTCICNPGYMG-AICSDQIDECY--SSPCLNDGRC 622
Query: 468 VNIDGGFRCECFTENCELSC 487
+++ G++C C ++C
Sbjct: 623 IDLVNGYQCNCQPGTSGVNC 642
Score = 79.8 bits (188), Expect = 3e-14
Identities = 74/261 (28%), Positives = 112/261 (42%), Gaps = 38/261 (14%)
Query: 224 CSCVHGEITCRPVECDRA--ECK-NPVLHPGECCPTCLR-QCLLWGNLYEHGERFAPKEC 279
C C+ G + V C+ EC+ NP ++ G+C R QCL + +C
Sbjct: 480 CLCMPG---FKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC 536
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC 339
+ C +G +C +D C F+ G C+ +D C+ C + C
Sbjct: 537 SSTPCLNG-AKC--IDHPNG---YECQCATGFT--GVLCE--ENIDNCDPD-PC-HHGQC 584
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ YTC CN G+ G C D +DEC + C ++ RC+++V GY C C G
Sbjct: 585 QDGIDSYTCICNPGYMG--AICSDQIDEC------YSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 399 YTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEG 457
+ NC + D+C N C +C + Y+C C G+ G + +DEC
Sbjct: 637 TSG---VNCEINFDDCASNP--C-IHGICMDGINRYSCVCSPGFTGQRCN-IDIDEC--A 687
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S+ C A C+N GFRC C
Sbjct: 688 SNPCRKGATCINGVNGFRCIC 708
Score = 76.6 bits (180), Expect = 3e-13
Identities = 62/219 (28%), Positives = 91/219 (41%), Gaps = 33/219 (15%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
ECA C G C+ C C P Q G C++ VD C C
Sbjct: 1152 ECASNPCQHG-ATCSDFIGGYRCE---CVPGYQ----GVNCEY--EVDECQ-NQPCQNGG 1200
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC++L + C C G +G L C++ +D+C G HC + +C++ +GGY C+CL
Sbjct: 1201 TCIDLVNHFKCSCPPGTRG--LLCEENIDDCAR-----GPHCLNGGQCMDRIGGYSCRCL 1253
Query: 397 GGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G+ + C +++EC N C Y C CR + G + VD C
Sbjct: 1254 PGFAGE---RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG-RHCETFVDVCP 1309
Query: 456 EGSHTCHHSARCV---NIDGGFRCEC---FT-ENCELSC 487
+ C + C N+ GF C C F+ C+ SC
Sbjct: 1310 Q--MPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/156 (30%), Positives = 71/156 (45%), Gaps = 18/156 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + C + ATC+N + C C +G Q V+EC +HG+
Sbjct: 683 IDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-VNECLSNPCIHGN------- 733
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C + GY C C G+ NC EVD+ E ++ C C N Y C C+ G++
Sbjct: 734 CTGGLSGYKCLCDAGWVG---INC-EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK- 788
Query: 444 DGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY C +++DEC S+ C + C + G+ C C
Sbjct: 789 -GYNCQVNIDEC--ASNPCLNQGTCFDDISGYTCHC 821
Score = 72.1 bits (169), Expect = 6e-12
Identities = 83/305 (27%), Positives = 112/305 (36%), Gaps = 44/305 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP-- 255
DC + NG DG + C C+ G T + D EC P + G C
Sbjct: 914 DCLANPCQNGGSCMDGV----NTFSCLCLPG-FTGDKCQTDMNECLSEPCKNGGTCSDYV 968
Query: 256 ---TCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
TC Q G E+ EC E C +G T VD C P F+
Sbjct: 969 NSYTCKCQAGFDGVHCENNIN----ECTESSCFNGG---TCVD---GINSFSCLCPVGFT 1018
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAG 371
G C ++ C+ H C TC++ Y C C G+ G CQ V+ C +
Sbjct: 1019 --GSFCLH--EINECS-SHPCLNEGTCVDGLGTYRCSCPLGYTGKN--CQTLVNLCSRSP 1071
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQC----LGGYTRKDKFNCVEVDECEGNT--HGCHADAV 425
C + CV C C G Y +C G H C V
Sbjct: 1072 ------CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCEL 485
C N ++ C+C GY G Y +DEC S+ C H A C + GG+RCEC +
Sbjct: 1126 CINAGNTHYCQCPLGYTGS-YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGV 1182
Query: 486 SCSWQ 490
+C ++
Sbjct: 1183 NCEYE 1187
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/177 (27%), Positives = 73/177 (41%), Gaps = 35/177 (19%)
Query: 317 CCKFCPGVDYCNMGHS-CDENATCMNLN--TKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
CC C G+ C C+ + T Y CKC +GF G+ CQ D C++
Sbjct: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGY-CKCPEGFLGE--YCQHRDPCEK---- 70
Query: 374 HGHHCHSNTRCVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNT-HGCHADAVCTN-- 428
+ C + CV ++G C+C G+T +D C+ +T H C C N
Sbjct: 71 --NRCQNGGTCVAQAMLGKATCRCASGFTGED---------CQYSTSHPCFVSRPCLNGG 119
Query: 429 -----TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ +Y C C+ G+ G C D C SH C + + C + F C+C T
Sbjct: 120 TCHMLSRDTYECTCQVGFTGK--ECQWTDACL--SHPCANGSTCTTVANQFSCKCLT 172
Score = 56.0 bits (129), Expect = 4e-07
Identities = 78/301 (25%), Positives = 107/301 (35%), Gaps = 44/301 (14%)
Query: 200 CQKSCYSNGTVHADGATWQR---DCNRCS---CVHGEITCRPVECDRAECKNPVLHPGEC 253
C V + G T QR D + C+ C G V R C HP
Sbjct: 659 CMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS-- 716
Query: 254 CPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQF 311
C + + +CL N HG +C+C G + C VD C PC
Sbjct: 717 CYSQVNECL--SNPCIHGNCTGGLSGYKCLCDAGWVGINC-EVDKN-ECLSNPCQNGGTC 772
Query: 312 S--VPGECCKFCPGVDYCNMGHSCDENAT--CMNLNT------KYTCKCNQGFQGDGLTC 361
V G C G N + DE A+ C+N T YTC C + G C
Sbjct: 773 DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN--C 830
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVG--GYVCQCLGGYTRKDKFNC-VEVDECEGNTH 418
Q V + C + C Y C C G+ + C +++DEC
Sbjct: 831 QTV-----LAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKP- 881
Query: 419 GCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCE 477
C +C NT GSY C C G+ G C +D+C ++ C + C++ F C
Sbjct: 882 -CMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCL 936
Query: 478 C 478
C
Sbjct: 937 C 937
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/291 (24%), Positives = 109/291 (37%), Gaps = 42/291 (14%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGE--ITCRPVECDRAECKNPVLHPGECCPTCLRQC 261
C SN H + RC CV G + C E D EC+N G TC+
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCE-YEVD--ECQNQPCQNGG---TCI--- 1203
Query: 262 LLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS---VPGECC 318
+L H + P +C + C R P D +S +PG
Sbjct: 1204 ----DLVNHFKCSCPPGTRGLLCEENIDDCAR-GPHCLNGGQCMDRIGGYSCRCLPGFAG 1258
Query: 319 KFCPG-VDYCNMGHSCDENAT--CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
+ C G ++ C + + C + C+ L Y C C F G C+ VD C + L+
Sbjct: 1259 ERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRH--CETFVDVCPQMPCLN 1315
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C + N+ G++C+C G++ + + +C +V C C +T
Sbjct: 1316 GGTCAVAS---NMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQCVHTASGP 1364
Query: 434 TCRC---RDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
C C RD G + C H C ++S +C G RCE +T
Sbjct: 1365 RCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 104 bits (249), Expect = 1e-21
Identities = 84/283 (29%), Positives = 132/283 (46%), Gaps = 32/283 (11%)
Query: 213 DGATWQR---DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYE 269
+G+T +R DC C +G + V + C+ P G+ C + +CLL N +
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310
Query: 270 HGERFAPKECAE-CVCHDG--NMQCTRVDPELA---C-PRLPC-DPPQQFSV---PGECC 318
+G A + CVC +G C+ + A C P C D FS G+
Sbjct: 311 NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370
Query: 319 KFCPGVDYCNMGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
C D C + + C + A C LN +Y C C QG++G T +DVDEC A + +
Sbjct: 371 LLCHLDDAC-ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT-EDVDECAMA---NSN 425
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTC 435
C +CVN G + C+CL GY C ++++EC + C DA C + G +TC
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYAGP---RCEMDINECHSDP--CQNDATCLDKIGGFTC 480
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++G + + ++EC S+ C ++ +CV+ F+C C
Sbjct: 481 LCMPGFKG-VHCELEINECQ--SNPCVNNGQCVDKVNRFQCLC 520
Score = 88.6 bits (210), Expect = 6e-17
Identities = 54/154 (35%), Positives = 72/154 (46%), Gaps = 20/154 (12%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ + C TC NL Y C C +GF+ G CQ ++DEC + C + C +
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECA------SNPCLNQGTCFDD 813
Query: 388 VGGYVCQCLGGYTRKDKFNCVEV-DECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGD 444
+ GY C C+ YT K NC V C N C AVC +P SYTC C G++G
Sbjct: 814 ISGYTCHCVLPYTGK---NCQTVLAPCSPNP--CENAAVCKESPNFESYTCLCAPGWQGQ 868
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T + +DEC S C + C N G + CEC
Sbjct: 869 RCT-IDIDECI--SKPCMNHGLCHNTQGSYMCEC 899
Score = 86.6 bits (205), Expect = 2e-16
Identities = 80/297 (26%), Positives = 113/297 (38%), Gaps = 37/297 (12%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRCSCVH----GEITCRPVECDRAE-CKNPVLHPGE 252
C C + H D R N +CV G+ TCR E C+ HP
Sbjct: 51 CKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCF 110
Query: 253 CCPTCLR--QC-LLWGNLYEHGER--FAPKECA---ECVCHD--GNMQCTRVDPELACPR 302
CL C +L + YE + F KEC C+ H CT V + +C
Sbjct: 111 VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
L G+ C+ V+ C++ C TC+NL Y C+C QGF G
Sbjct: 171 LT-------GFTGQKCE--TDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSL 221
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCH 421
V C + ++G C + C CL G+ + C +D+C H C
Sbjct: 222 YV-PCAPSPCVNGGTCRQTGDFT-----FECNCLPGF---EGSTCERNIDDCP--NHRCQ 270
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC + +Y CRC + G + VDEC + C + C N +GG+ C C
Sbjct: 271 NGGVCVDGVNTYNCRCPPQWTGQ-FCTEDVDECLLQPNACQNGGTCANRNGGYGCVC 326
Score = 83.4 bits (197), Expect = 2e-15
Identities = 71/260 (27%), Positives = 108/260 (41%), Gaps = 33/260 (12%)
Query: 243 CKNPVLHPGECCPTCLRQCLLWG-NLYEHGERFAPKECA-ECVCHDGNMQCTRVDPEL-A 299
C P + G C + +C + N EH + + A C C G R + ++
Sbjct: 401 CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG-PRCEMDINE 459
Query: 300 CPRLPC--DPPQQFSVPGECCKFCPGVD--YCNM------GHSCDENATCMNLNTKYTCK 349
C PC D + G C PG +C + + C N C++ ++ C
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
Query: 350 CNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C GF G CQ D+D+C L+G +C++ GY CQC G+T C
Sbjct: 520 CPPGFTGP--VCQIDIDDCSSTPCLNG------AKCIDHPNGYECQCATGFT---GVLCE 568
Query: 409 E-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
E +D C+ + CH C + SYTC C GY G +DEC S C + RC
Sbjct: 569 ENIDNCDPDP--CH-HGQCQDGIDSYTCICNPGYMG-AICSDQIDECY--SSPCLNDGRC 622
Query: 468 VNIDGGFRCECFTENCELSC 487
+++ G++C C ++C
Sbjct: 623 IDLVNGYQCNCQPGTSGVNC 642
Score = 79.8 bits (188), Expect = 3e-14
Identities = 74/261 (28%), Positives = 112/261 (42%), Gaps = 38/261 (14%)
Query: 224 CSCVHGEITCRPVECDRA--ECK-NPVLHPGECCPTCLR-QCLLWGNLYEHGERFAPKEC 279
C C+ G + V C+ EC+ NP ++ G+C R QCL + +C
Sbjct: 480 CLCMPG---FKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC 536
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC 339
+ C +G +C +D C F+ G C+ +D C+ C + C
Sbjct: 537 SSTPCLNG-AKC--IDHPNG---YECQCATGFT--GVLCE--ENIDNCDPD-PC-HHGQC 584
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ YTC CN G+ G C D +DEC + C ++ RC+++V GY C C G
Sbjct: 585 QDGIDSYTCICNPGYMG--AICSDQIDEC------YSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 399 YTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEG 457
+ NC + D+C N C +C + Y+C C G+ G + +DEC
Sbjct: 637 TSG---VNCEINFDDCASNP--C-IHGICMDGINRYSCVCSPGFTGQRCN-IDIDEC--A 687
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S+ C A C+N GFRC C
Sbjct: 688 SNPCRKGATCINGVNGFRCIC 708
Score = 76.6 bits (180), Expect = 3e-13
Identities = 62/219 (28%), Positives = 91/219 (41%), Gaps = 33/219 (15%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
ECA C G C+ C C P Q G C++ VD C C
Sbjct: 1152 ECASNPCQHG-ATCSDFIGGYRCE---CVPGYQ----GVNCEY--EVDECQ-NQPCQNGG 1200
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC++L + C C G +G L C++ +D+C G HC + +C++ +GGY C+CL
Sbjct: 1201 TCIDLVNHFKCSCPPGTRG--LLCEENIDDCAR-----GPHCLNGGQCMDRIGGYSCRCL 1253
Query: 397 GGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G+ + C +++EC N C Y C CR + G + VD C
Sbjct: 1254 PGFAGE---RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG-RHCETFVDVCP 1309
Query: 456 EGSHTCHHSARCV---NIDGGFRCEC---FT-ENCELSC 487
+ C + C N+ GF C C F+ C+ SC
Sbjct: 1310 Q--MPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/156 (30%), Positives = 71/156 (45%), Gaps = 18/156 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + C + ATC+N + C C +G Q V+EC +HG+
Sbjct: 683 IDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-VNECLSNPCIHGN------- 733
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C + GY C C G+ NC EVD+ E ++ C C N Y C C+ G++
Sbjct: 734 CTGGLSGYKCLCDAGWVG---INC-EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK- 788
Query: 444 DGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY C +++DEC S+ C + C + G+ C C
Sbjct: 789 -GYNCQVNIDEC--ASNPCLNQGTCFDDISGYTCHC 821
Score = 72.1 bits (169), Expect = 6e-12
Identities = 83/305 (27%), Positives = 112/305 (36%), Gaps = 44/305 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP-- 255
DC + NG DG + C C+ G T + D EC P + G C
Sbjct: 914 DCLANPCQNGGSCMDGV----NTFSCLCLPG-FTGDKCQTDMNECLSEPCKNGGTCSDYV 968
Query: 256 ---TCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
TC Q G E+ EC E C +G T VD C P F+
Sbjct: 969 NSYTCKCQAGFDGVHCENNIN----ECTESSCFNGG---TCVD---GINSFSCLCPVGFT 1018
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAG 371
G C ++ C+ H C TC++ Y C C G+ G CQ V+ C +
Sbjct: 1019 --GSFCLH--EINECS-SHPCLNEGTCVDGLGTYRCSCPLGYTGKN--CQTLVNLCSRSP 1071
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQC----LGGYTRKDKFNCVEVDECEGNT--HGCHADAV 425
C + CV C C G Y +C G H C V
Sbjct: 1072 ------CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCEL 485
C N ++ C+C GY G Y +DEC S+ C H A C + GG+RCEC +
Sbjct: 1126 CINAGNTHYCQCPLGYTGS-YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGV 1182
Query: 486 SCSWQ 490
+C ++
Sbjct: 1183 NCEYE 1187
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/177 (27%), Positives = 73/177 (41%), Gaps = 35/177 (19%)
Query: 317 CCKFCPGVDYCNMGHS-CDENATCMNLN--TKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
CC C G+ C C+ + T Y CKC +GF G+ CQ D C++
Sbjct: 18 CCATPAHALQCRDGYEPCVNEGMCVTYHNGTGY-CKCPEGFLGE--YCQHRDPCEK---- 70
Query: 374 HGHHCHSNTRCVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNT-HGCHADAVCTN-- 428
+ C + CV ++G C+C G+T +D C+ +T H C C N
Sbjct: 71 --NRCQNGGTCVAQAMLGKATCRCASGFTGED---------CQYSTSHPCFVSRPCLNGG 119
Query: 429 -----TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ +Y C C+ G+ G C D C SH C + + C + F C+C T
Sbjct: 120 TCHMLSRDTYECTCQVGFTGK--ECQWTDACL--SHPCANGSTCTTVANQFSCKCLT 172
Score = 56.0 bits (129), Expect = 4e-07
Identities = 78/301 (25%), Positives = 107/301 (35%), Gaps = 44/301 (14%)
Query: 200 CQKSCYSNGTVHADGATWQR---DCNRCS---CVHGEITCRPVECDRAECKNPVLHPGEC 253
C V + G T QR D + C+ C G V R C HP
Sbjct: 659 CMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS-- 716
Query: 254 CPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQF 311
C + + +CL N HG +C+C G + C VD C PC
Sbjct: 717 CYSQVNECL--SNPCIHGNCTGGLSGYKCLCDAGWVGINC-EVDKN-ECLSNPCQNGGTC 772
Query: 312 S--VPGECCKFCPGVDYCNMGHSCDENAT--CMNLNT------KYTCKCNQGFQGDGLTC 361
V G C G N + DE A+ C+N T YTC C + G C
Sbjct: 773 DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN--C 830
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVG--GYVCQCLGGYTRKDKFNC-VEVDECEGNTH 418
Q V + C + C Y C C G+ + C +++DEC
Sbjct: 831 QTV-----LAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKP- 881
Query: 419 GCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCE 477
C +C NT GSY C C G+ G C +D+C ++ C + C++ F C
Sbjct: 882 -CMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCL 936
Query: 478 C 478
C
Sbjct: 937 C 937
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/291 (24%), Positives = 109/291 (37%), Gaps = 42/291 (14%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGE--ITCRPVECDRAECKNPVLHPGECCPTCLRQC 261
C SN H + RC CV G + C E D EC+N G TC+
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCE-YEVD--ECQNQPCQNGG---TCI--- 1203
Query: 262 LLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS---VPGECC 318
+L H + P +C + C R P D +S +PG
Sbjct: 1204 ----DLVNHFKCSCPPGTRGLLCEENIDDCAR-GPHCLNGGQCMDRIGGYSCRCLPGFAG 1258
Query: 319 KFCPG-VDYCNMGHSCDENAT--CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
+ C G ++ C + + C + C+ L Y C C F G C+ VD C + L+
Sbjct: 1259 ERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRH--CETFVDVCPQMPCLN 1315
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C + N+ G++C+C G++ + + +C +V C C +T
Sbjct: 1316 GGTCAVAS---NMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQCVHTASGP 1364
Query: 434 TCRC---RDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
C C RD G + C H C ++S +C G RCE +T
Sbjct: 1365 RCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 104 bits (249), Expect = 1e-21
Identities = 84/283 (29%), Positives = 132/283 (46%), Gaps = 32/283 (11%)
Query: 213 DGATWQR---DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYE 269
+G+T +R DC C +G + V + C+ P G+ C + +CLL N +
Sbjct: 253 EGSTCERNIDDCPNHRCQNGGVCVDGV--NTYNCRCPPQWTGQFCTEDVDECLLQPNACQ 310
Query: 270 HGERFAPKECAE-CVCHDG--NMQCTRVDPELA---C-PRLPC-DPPQQFSV---PGECC 318
+G A + CVC +G C+ + A C P C D FS G+
Sbjct: 311 NGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAG 370
Query: 319 KFCPGVDYCNMGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
C D C + + C + A C LN +Y C C QG++G T +DVDEC A + +
Sbjct: 371 LLCHLDDAC-ISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT-EDVDECAMA---NSN 425
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTC 435
C +CVN G + C+CL GY C ++++EC + C DA C + G +TC
Sbjct: 426 PCEHAGKCVNTDGAFHCECLKGYAGP---RCEMDINECHSDP--CQNDATCLDKIGGFTC 480
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++G + + ++EC S+ C ++ +CV+ F+C C
Sbjct: 481 LCMPGFKG-VHCELEINECQ--SNPCVNNGQCVDKVNRFQCLC 520
Score = 88.6 bits (210), Expect = 6e-17
Identities = 54/154 (35%), Positives = 72/154 (46%), Gaps = 20/154 (12%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ + C TC NL Y C C +GF+ G CQ ++DEC + C + C +
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECA------SNPCLNQGTCFDD 813
Query: 388 VGGYVCQCLGGYTRKDKFNCVEV-DECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGD 444
+ GY C C+ YT K NC V C N C AVC +P SYTC C G++G
Sbjct: 814 ISGYTCHCVLPYTGK---NCQTVLAPCSPNP--CENAAVCKESPNFESYTCLCAPGWQGQ 868
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T + +DEC S C + C N G + CEC
Sbjct: 869 RCT-IDIDECI--SKPCMNHGLCHNTQGSYMCEC 899
Score = 87.0 bits (206), Expect = 2e-16
Identities = 80/297 (26%), Positives = 113/297 (38%), Gaps = 37/297 (12%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRCSCVH----GEITCRPVECDRAE-CKNPVLHPGE 252
C C + H D R N +CV G+ TCR E C+ HP
Sbjct: 51 CKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCF 110
Query: 253 CCPTCLR--QC-LLWGNLYEHGER--FAPKECA---ECVCHD--GNMQCTRVDPELACPR 302
CL C +L + YE + F KEC C+ H CT V + +C
Sbjct: 111 VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
L G+ C+ V+ C++ C TC+NL Y C+C QGF G
Sbjct: 171 LT-------GFTGQKCE--TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL 221
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCH 421
V C + ++G C + C CL G+ + C +D+C H C
Sbjct: 222 YV-PCAPSPCVNGGTCRQTGDFT-----FECNCLPGF---EGSTCERNIDDCP--NHRCQ 270
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC + +Y CRC + G + VDEC + C + C N +GG+ C C
Sbjct: 271 NGGVCVDGVNTYNCRCPPQWTGQ-FCTEDVDECLLQPNACQNGGTCANRNGGYGCVC 326
Score = 83.4 bits (197), Expect = 2e-15
Identities = 71/260 (27%), Positives = 108/260 (41%), Gaps = 33/260 (12%)
Query: 243 CKNPVLHPGECCPTCLRQCLLWG-NLYEHGERFAPKECA-ECVCHDGNMQCTRVDPEL-A 299
C P + G C + +C + N EH + + A C C G R + ++
Sbjct: 401 CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAG-PRCEMDINE 459
Query: 300 CPRLPC--DPPQQFSVPGECCKFCPGVD--YCNM------GHSCDENATCMNLNTKYTCK 349
C PC D + G C PG +C + + C N C++ ++ C
Sbjct: 460 CHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCL 519
Query: 350 CNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCV 408
C GF G CQ D+D+C L+G +C++ GY CQC G+T C
Sbjct: 520 CPPGFTGP--VCQIDIDDCSSTPCLNG------AKCIDHPNGYECQCATGFT---GVLCE 568
Query: 409 E-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARC 467
E +D C+ + CH C + SYTC C GY G +DEC S C + RC
Sbjct: 569 ENIDNCDPDP--CH-HGQCQDGIDSYTCICNPGYMG-AICSDQIDECY--SSPCLNDGRC 622
Query: 468 VNIDGGFRCECFTENCELSC 487
+++ G++C C ++C
Sbjct: 623 IDLVNGYQCNCQPGTSGVNC 642
Score = 79.8 bits (188), Expect = 3e-14
Identities = 74/261 (28%), Positives = 112/261 (42%), Gaps = 38/261 (14%)
Query: 224 CSCVHGEITCRPVECDRA--ECK-NPVLHPGECCPTCLR-QCLLWGNLYEHGERFAPKEC 279
C C+ G + V C+ EC+ NP ++ G+C R QCL + +C
Sbjct: 480 CLCMPG---FKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC 536
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC 339
+ C +G +C +D C F+ G C+ +D C+ C + C
Sbjct: 537 SSTPCLNG-AKC--IDHPNG---YECQCATGFT--GVLCE--ENIDNCDPD-PC-HHGQC 584
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ YTC CN G+ G C D +DEC + C ++ RC+++V GY C C G
Sbjct: 585 QDGIDSYTCICNPGYMG--AICSDQIDEC------YSSPCLNDGRCIDLVNGYQCNCQPG 636
Query: 399 YTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEG 457
+ NC + D+C N C +C + Y+C C G+ G + +DEC
Sbjct: 637 TSG---VNCEINFDDCASNP--C-IHGICMDGINRYSCVCSPGFTGQRCN-IDIDEC--A 687
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S+ C A C+N GFRC C
Sbjct: 688 SNPCRKGATCINGVNGFRCIC 708
Score = 76.6 bits (180), Expect = 3e-13
Identities = 62/219 (28%), Positives = 91/219 (41%), Gaps = 33/219 (15%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
ECA C G C+ C C P Q G C++ VD C C
Sbjct: 1152 ECASNPCQHG-ATCSDFIGGYRCE---CVPGYQ----GVNCEY--EVDECQ-NQPCQNGG 1200
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC++L + C C G +G L C++ +D+C G HC + +C++ +GGY C+CL
Sbjct: 1201 TCIDLVNHFKCSCPPGTRG--LLCEENIDDCAR-----GPHCLNGGQCMDRIGGYSCRCL 1253
Query: 397 GGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G+ + C +++EC N C Y C CR + G + VD C
Sbjct: 1254 PGFAGE---RCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTG-RHCETFVDVCP 1309
Query: 456 EGSHTCHHSARCV---NIDGGFRCEC---FT-ENCELSC 487
+ C + C N+ GF C C F+ C+ SC
Sbjct: 1310 Q--MPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSC 1346
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/156 (30%), Positives = 71/156 (45%), Gaps = 18/156 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + C + ATC+N + C C +G Q V+EC +HG+
Sbjct: 683 IDEC-ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-VNECLSNPCIHGN------- 733
Query: 384 CVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C + GY C C G+ NC EVD+ E ++ C C N Y C C+ G++
Sbjct: 734 CTGGLSGYKCLCDAGWVG---INC-EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFK- 788
Query: 444 DGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY C +++DEC S+ C + C + G+ C C
Sbjct: 789 -GYNCQVNIDEC--ASNPCLNQGTCFDDISGYTCHC 821
Score = 72.1 bits (169), Expect = 6e-12
Identities = 83/305 (27%), Positives = 112/305 (36%), Gaps = 44/305 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP-- 255
DC + NG DG + C C+ G T + D EC P + G C
Sbjct: 914 DCLANPCQNGGSCMDGV----NTFSCLCLPG-FTGDKCQTDMNECLSEPCKNGGTCSDYV 968
Query: 256 ---TCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
TC Q G E+ EC E C +G T VD C P F+
Sbjct: 969 NSYTCKCQAGFDGVHCENNIN----ECTESSCFNGG---TCVD---GINSFSCLCPVGFT 1018
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAG 371
G C ++ C+ H C TC++ Y C C G+ G CQ V+ C +
Sbjct: 1019 --GSFCLH--EINECS-SHPCLNEGTCVDGLGTYRCSCPLGYTGKN--CQTLVNLCSRSP 1071
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQC----LGGYTRKDKFNCVEVDECEGNT--HGCHADAV 425
C + CV C C G Y +C G H C V
Sbjct: 1072 ------CKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGV 1125
Query: 426 CTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCEL 485
C N ++ C+C GY G Y +DEC S+ C H A C + GG+RCEC +
Sbjct: 1126 CINAGNTHYCQCPLGYTGS-YCEEQLDECA--SNPCQHGATCSDFIGGYRCECVPGYQGV 1182
Query: 486 SCSWQ 490
+C ++
Sbjct: 1183 NCEYE 1187
Score = 63.3 bits (147), Expect = 3e-09
Identities = 49/177 (27%), Positives = 73/177 (41%), Gaps = 35/177 (19%)
Query: 317 CCKFCPGVDYCNMGHS-CDENATCMNLN--TKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
CC C G+ C C+ + T Y CKC +GF G+ CQ D C++
Sbjct: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGY-CKCPEGFLGE--YCQHRDPCEK---- 70
Query: 374 HGHHCHSNTRCVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNT-HGCHADAVCTN-- 428
+ C + CV ++G C+C G+T +D C+ +T H C C N
Sbjct: 71 --NRCQNGGTCVAQAMLGKATCRCASGFTGED---------CQYSTSHPCFVSRPCLNGG 119
Query: 429 -----TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ +Y C C+ G+ G C D C SH C + + C + F C+C T
Sbjct: 120 TCHMLSRDTYECTCQVGFTGK--ECQWTDACL--SHPCANGSTCTTVANQFSCKCLT 172
Score = 56.0 bits (129), Expect = 4e-07
Identities = 78/301 (25%), Positives = 107/301 (35%), Gaps = 44/301 (14%)
Query: 200 CQKSCYSNGTVHADGATWQR---DCNRCS---CVHGEITCRPVECDRAECKNPVLHPGEC 253
C V + G T QR D + C+ C G V R C HP
Sbjct: 659 CMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPS-- 716
Query: 254 CPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQF 311
C + + +CL N HG +C+C G + C VD C PC
Sbjct: 717 CYSQVNECL--SNPCIHGNCTGGLSGYKCLCDAGWVGINC-EVDKN-ECLSNPCQNGGTC 772
Query: 312 S--VPGECCKFCPGVDYCNMGHSCDENAT--CMNLNT------KYTCKCNQGFQGDGLTC 361
V G C G N + DE A+ C+N T YTC C + G C
Sbjct: 773 DNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN--C 830
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVG--GYVCQCLGGYTRKDKFNC-VEVDECEGNTH 418
Q V + C + C Y C C G+ + C +++DEC
Sbjct: 831 QTV-----LAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQ---RCTIDIDECISKP- 881
Query: 419 GCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCE 477
C +C NT GSY C C G+ G C +D+C ++ C + C++ F C
Sbjct: 882 -CMNHGLCHNTQGSYMCECPPGF--SGMDCEEDIDDCL--ANPCQNGGSCMDGVNTFSCL 936
Query: 478 C 478
C
Sbjct: 937 C 937
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/291 (24%), Positives = 109/291 (37%), Gaps = 42/291 (14%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGE--ITCRPVECDRAECKNPVLHPGECCPTCLRQC 261
C SN H + RC CV G + C E D EC+N G TC+
Sbjct: 1153 CASNPCQHGATCSDFIGGYRCECVPGYQGVNCE-YEVD--ECQNQPCQNGG---TCI--- 1203
Query: 262 LLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS---VPGECC 318
+L H + P +C + C R P D +S +PG
Sbjct: 1204 ----DLVNHFKCSCPPGTRGLLCEENIDDCAR-GPHCLNGGQCMDRIGGYSCRCLPGFAG 1258
Query: 319 KFCPG-VDYCNMGHSCDENAT--CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
+ C G ++ C + + C + C+ L Y C C F G C+ VD C + L+
Sbjct: 1259 ERCEGDINEC-LSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRH--CETFVDVCPQMPCLN 1315
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
G C + N+ G++C+C G++ + + +C +V C C +T
Sbjct: 1316 GGTCAVAS---NMPDGFICRCPPGFSGARCQSSCGQVK--------CRKGEQCVHTASGP 1364
Query: 434 TCRC---RDGYEGDGYT-CMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
C C RD G + C H C ++S +C G RCE +T
Sbjct: 1365 RCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYT 1415
>AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein.
Length = 509
Score = 103 bits (248), Expect = 2e-21
Identities = 68/218 (31%), Positives = 92/218 (42%), Gaps = 32/218 (14%)
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCDPP 308
G+C P C +C +HGE P +C CH G C + E PC
Sbjct: 54 GQCQPVCQPRC-------KHGECIGPNKCK---CHPGYAGKTCNQDLNECGLKPRPCKHR 103
Query: 309 QQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTC-------KCNQGFQG----- 356
+ C G G SC TC N +Y C +C G
Sbjct: 104 CMNTYGSYKCYCLNGYMLMPDG-SCSSALTCSMANCQYGCDVVKGQIRCQCPSPGLHLAP 162
Query: 357 DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK---DKFNCVEVDEC 413
DG TC DVDEC C +CVN G Y+C+C G+ K+ C ++DEC
Sbjct: 163 DGRTCVDVDECATGRA----SCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDEC 218
Query: 414 EGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV 451
+ C + A C N GSY C+C++GY+GDG TC+++
Sbjct: 219 SLGQYQCSSFARCYNVRGSYKCKCKEGYQGDGLTCVYI 256
Score = 91.5 bits (217), Expect = 9e-18
Identities = 52/148 (35%), Positives = 67/148 (45%), Gaps = 17/148 (11%)
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
CMN Y C C G+ DG +C C A +G C V G CQC
Sbjct: 104 CMNTYGSYKCYCLNGYMLMPDG-SCSSALTCSMANCQYG--------CDVVKGQIRCQCP 154
Query: 397 --GGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE----GDGYTCMH 450
G + D CV+VDEC C C NT GSY C+C G++ G Y C
Sbjct: 155 SPGLHLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHD 214
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCEC 478
+DEC+ G + C ARC N+ G ++C+C
Sbjct: 215 IDECSLGQYQCSSFARCYNVRGSYKCKC 242
Score = 37.1 bits (82), Expect = 0.20
Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 15/91 (16%)
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC 448
GG + C G+ R+ C V C+ H + + G C+C GY G TC
Sbjct: 39 GGRI-DCCWGWARQSWGQCQPV--CQPRCK--HGECI-----GPNKCKCHPGYAGK--TC 86
Query: 449 -MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
++EC C H RC+N G ++C C
Sbjct: 87 NQDLNECGLKPRPCKH--RCMNTYGSYKCYC 115
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 103 bits (248), Expect = 2e-21
Identities = 59/155 (38%), Positives = 80/155 (51%), Gaps = 18/155 (11%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
CN G +CD N +N K C C G+ G + QDVDEC L + C +C+N
Sbjct: 381 CNEGSNCDTNP----VNGKAICTCPSGYTGPACS-QDVDECS----LGANPCEHAGKCIN 431
Query: 387 VVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+G + CQCL GYT C ++V+EC N C DA C + G + C C GYEG
Sbjct: 432 TLGSFECQCLQGYTGP---RCEIDVNECVSNP--CQNDATCLDQIGEFQCICMPGYEG-V 485
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ ++ DEC S C H+ RC++ F+CEC T
Sbjct: 486 HCEVNTDEC--ASSPCLHNGRCLDKINEFQCECPT 518
Score = 96.3 bits (229), Expect = 3e-19
Identities = 78/282 (27%), Positives = 114/282 (40%), Gaps = 37/282 (13%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGEITC-RP-VECDRAECKNPVLHPGECCPT--CLR 259
C GT H + +++ C C H C RP V C + C+N G C PT
Sbjct: 189 CRHGGTCHNEVGSYR--CV-CRATHTGPNCERPYVPCSPSPCQNG----GTCRPTGDVTH 241
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
+C +C C +G V+ C P +++ G+ C
Sbjct: 242 ECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNT------YNCRCPPEWT--GQYCT 293
Query: 320 FCPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
VD C M ++C TC N + Y C C G+ G+ + +++D+C A HG C
Sbjct: 294 --EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS-ENIDDCASAACFHGATC 350
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP--GSYTCR 436
H V + C+C G T C D C N C+ + C P G C
Sbjct: 351 HDR------VASFYCECPHGRTG---LLCHLNDACISNP--CNEGSNCDTNPVNGKAICT 399
Query: 437 CRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C GY G + VDEC+ G++ C H+ +C+N G F C+C
Sbjct: 400 CPSGYTGPACS-QDVDECSLGANPCEHAGKCINTLGSFECQC 440
Score = 95.9 bits (228), Expect = 4e-19
Identities = 86/297 (28%), Positives = 122/297 (41%), Gaps = 44/297 (14%)
Query: 199 DC-QKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKN-PVLHPGECCPT 256
DC + SC++ GT DG + C C G T + D EC + P LH G C
Sbjct: 986 DCTESSCFNGGTC-VDGI----NSFTCLCPPG-FTGSYCQHDVNECDSQPCLHGGTCQDG 1039
Query: 257 C-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQC--TRVDPELACPR----LPCDPPQ 309
C +C + C C +G +C T CP L CD P
Sbjct: 1040 CGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG-KCWQTHTQYRCECPSGWTGLYCDVP- 1097
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQ 368
SV E GVD + C C++ + C+C G+ G C+D VDEC
Sbjct: 1098 --SVSCEVAAQRQGVDVARL---CQHGGLCVDAGNTHHCRCQAGYTGS--YCEDLVDECS 1150
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCT 427
+ C + C + +GGY C+C+ GY NC E+DEC +H C C
Sbjct: 1151 PSP------CQNGATCTDYLGGYSCKCVAGY---HGVNCSEEIDEC--LSHPCQNGGTCL 1199
Query: 428 NTPGSYTCRCRDGYEGDGYTCMHVDEC------TEGSHTCHHSARCVNIDGGFRCEC 478
+ P +Y C C G +G + ++VD+C S C ++ CV+ GG+ C C
Sbjct: 1200 DLPNTYKCSCPRGTQG-VHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC 1255
Score = 89.8 bits (213), Expect = 3e-17
Identities = 83/295 (28%), Positives = 121/295 (41%), Gaps = 43/295 (14%)
Query: 211 HADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEH 270
H + A CN S PV +A C P + G C + +C L N EH
Sbjct: 371 HLNDACISNPCNEGS----NCDTNPVN-GKAICTCPSGYTGPACSQDVDECSLGANPCEH 425
Query: 271 -GERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQ-FSVPGECCKFC-PGVD 325
G+ EC C G +C +D C PC GE C PG +
Sbjct: 426 AGKCINTLGSFECQCLQGYTGPRC-EIDVN-ECVSNPCQNDATCLDQIGEFQCICMPGYE 483
Query: 326 --YCNMGHS------CDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGH 376
+C + C N C++ ++ C+C GF G CQ DVDEC
Sbjct: 484 GVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGH--LCQYDVDECASTP----- 536
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTC 435
C + +C++ Y C C GYT +C V++DEC+ + CH + C + ++TC
Sbjct: 537 -CKNGAKCLDGPNTYTCVCTEGYTGT---HCEVDIDECDPDP--CHYGS-CKDGVATFTC 589
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT----ENCELS 486
CR GY G + +++EC+ S C H C + D + C C NCE++
Sbjct: 590 LCRPGYTGH-HCETNINECS--SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEIN 641
Score = 82.6 bits (195), Expect = 4e-15
Identities = 79/326 (24%), Positives = 123/326 (37%), Gaps = 43/326 (13%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGA-TWQRDCNR-CSCVHGEIT---CRPVECDRA 241
G + + + +C + NG DG T+ C + H E+ C P C
Sbjct: 519 GFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG 578
Query: 242 ECKNPVL---------HPGECCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDGNMQC 291
CK+ V + G C T + +C HG ++ A C C G
Sbjct: 579 SCKDGVATFTCLCRPGYTGHHCETNINECS--SQPCRHGGTCQDRDNAYLCFCLKGTTGP 636
Query: 292 TRVDPELACPRLPCDPPQQFS-VPGECCKFCPGV--DYCNM------GHSCDENATCMNL 342
C PCD + G C PG CN+ G+ C TC +
Sbjct: 637 NCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDG 696
Query: 343 NTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK 402
+TC+C +G+ D +V+EC +HG C + + GY C C G++
Sbjct: 697 INGFTCRCPEGYH-DPTCLSEVNECNSNPCVHG-------ACRDSLNGYKCDCDPGWSGT 748
Query: 403 DKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTC 461
NC + +ECE N C C + Y C CR+G+ G +++EC S+ C
Sbjct: 749 ---NCDINNNECESNP--CVNGGTCKDMTSGYVCTCREGFSGPNCQT-NINECA--SNPC 800
Query: 462 HHSARCVNIDGGFRCECFTENCELSC 487
+ C++ G++C C +C
Sbjct: 801 LNQGTCIDDVAGYKCNCLLPYTGATC 826
Score = 80.2 bits (189), Expect = 2e-14
Identities = 47/164 (28%), Positives = 73/164 (44%), Gaps = 13/164 (7%)
Query: 333 CDENATCMNL-NTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C TC + + C C GF G +++D+C G++C + CV+ V Y
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCE-ENIDDCP------GNNCKNGGACVDGVNTY 279
Query: 392 VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV 451
C+C +T ++ +VDEC+ + C C NT G Y C C +G+ G+ + ++
Sbjct: 280 NCRCPPEWT--GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS-ENI 336
Query: 452 DECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
D+C S C H A C + F CEC L C +S
Sbjct: 337 DDC--ASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Score = 79.0 bits (186), Expect = 5e-14
Identities = 76/273 (27%), Positives = 107/273 (39%), Gaps = 35/273 (12%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPK-E 278
DC C G TC + D EC + G C + +C GN +G
Sbjct: 644 DCASSPCDSG--TCLD-KIDGYECACEPGYTGSMCNINIDECA--GNPCHNGGTCEDGIN 698
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCPGVDYCNM---GHSCD 334
C C +G T + C PC + S+ G C PG N + C+
Sbjct: 699 GFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECE 758
Query: 335 EN-----ATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVV 388
N TC ++ + Y C C +GF G CQ +++EC + C + C++ V
Sbjct: 759 SNPCVNGGTCKDMTSGYVCTCREGFSGP--NCQTNINECA------SNPCLNQGTCIDDV 810
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGDGY 446
GY C CL YT C EV C C + S++C C G++G
Sbjct: 811 AGYKCNCLLPYTGA---TC-EVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQ-- 864
Query: 447 TC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
TC + ++EC C H A C N GG+RC C
Sbjct: 865 TCEVDINECV--LSPCRHGASCQNTHGGYRCHC 895
Score = 79.0 bits (186), Expect = 5e-14
Identities = 75/287 (26%), Positives = 117/287 (40%), Gaps = 33/287 (11%)
Query: 198 CDCQKS-CYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP 255
CD + C SN V+ C+C G + + + EC NP L+ G C
Sbjct: 750 CDINNNECESNPCVNGGTCKDMTSGYVCTCREG-FSGPNCQTNINECASNPCLNQGTCID 808
Query: 256 TCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
CLL AP CA C +G +C + + + C P +
Sbjct: 809 DVAGYKCNCLLPYTGATCEVVLAP--CAPSPCRNGG-ECRQSEDYES---FSCVCPTGWQ 862
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAG 371
G+ C+ ++ C + C A+C N + Y C C G+ G C+ D+D+C+
Sbjct: 863 --GQTCEV--DINECVLS-PCRHGASCQNTHGGYRCHCQAGYSGRN--CETDIDDCRP-- 913
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+ CH+ C + + C CL G+ + F +++EC + C A CT+
Sbjct: 914 ----NPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVD 965
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SYTC C G+ G + + +CTE S C + CV+ F C C
Sbjct: 966 SYTCTCPAGFSGI-HCENNTPDCTESS--CFNGGTCVDGINSFTCLC 1009
Score = 78.6 bits (185), Expect = 6e-14
Identities = 53/164 (32%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLH 374
GE C +D C +C ATC + + C+C G GL C D C
Sbjct: 329 GEDCS--ENIDDCASA-ACFHGATCHDRVASFYCECPHG--RTGLLCHLNDACISNPCNE 383
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
G +C +N V G +C C GYT +VDEC + C C NT GS+
Sbjct: 384 GSNCDTNP----VNGKAICTCPSGYTGPACSQ--DVDECSLGANPCEHAGKCINTLGSFE 437
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+C GY G + V+EC S+ C + A C++ G F+C C
Sbjct: 438 CQCLQGYTGPRCE-IDVNECV--SNPCQNDATCLDQIGEFQCIC 478
Score = 75.4 bits (177), Expect = 6e-13
Identities = 49/162 (30%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGG--LHGHHCHS 380
+D C + H C TC++L Y C C +G Q G+ C+ +VD+C C +
Sbjct: 1184 IDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQ--GVHCEINVDDCNPPVDPVSRSPKCFN 1240
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
N CV+ VGGY C C G+ + C +V+EC N C + C CR
Sbjct: 1241 NGTCVDQVGGYSCTCPPGFVGE---RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1297
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCV---NIDGGFRCEC 478
G+ G C V +G C + C N GF C+C
Sbjct: 1298 GH--TGRRCESVINGCKGK-PCKNGGTCAVASNTARGFICKC 1336
Score = 68.9 bits (161), Expect = 5e-11
Identities = 78/300 (26%), Positives = 113/300 (37%), Gaps = 38/300 (12%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCL 258
DC+ + NG DG + C C+ G E D EC + G C C+
Sbjct: 910 DCRPNPCHNGGSCTDGI----NTAFCDCLPG-FRGTFCEEDINECASDPCRNGANCTDCV 964
Query: 259 RQ--CLLWGNLYE-HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPG 315
C H E P +C E C +G T VD C P F+ G
Sbjct: 965 DSYTCTCPAGFSGIHCENNTP-DCTESSCFNGG---TCVD---GINSFTCLCPPGFT--G 1015
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
C+ V+ C+ C TC + Y C C QG+ G CQ+ V C +
Sbjct: 1016 SYCQH--DVNECD-SQPCLHGGTCQDGCGSYRCTCPQGYTGPN--CQNLVHWCDSSP--- 1067
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRK----DKFNCVEVDECEGNTHG--CHADAVCTN 428
C + +C Y C+C G+T +C + +G C +C +
Sbjct: 1068 ---CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVD 1124
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
++ CRC+ GY G Y VDEC+ C + A C + GG+ C+C ++CS
Sbjct: 1125 AGNTHHCRCQAGYTGS-YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCS 1181
Score = 64.5 bits (150), Expect = 1e-09
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHS 380
P VD + C N TC++ Y+C C GF G+ C+ DV+EC +
Sbjct: 1227 PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE--RCEGDVNECLS----NPCDARG 1280
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCVEV-DECEGN-THGCHADAVCTNTPGSYTCRCR 438
CV V + C+C G+T + C V + C+G AV +NT + C+C
Sbjct: 1281 TQNCVQRVNDFHCECRAGHTGR---RCESVINGCKGKPCKNGGTCAVASNTARGFICKCP 1337
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+E G TC + D T GS C + C++ C C
Sbjct: 1338 AGFE--GATCEN-DARTCGSLRCLNGGTCISGPRSPTCLC 1374
Score = 59.3 bits (137), Expect = 4e-08
Identities = 54/218 (24%), Positives = 77/218 (35%), Gaps = 33/218 (15%)
Query: 291 CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-----CDENATCMNLNTK 345
C + P LA C P + + G C+ G + C G + C + C++ K
Sbjct: 10 CLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCK 69
Query: 346 ---------------YTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
Y C C GF G + C +G C T +
Sbjct: 70 NAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLT-----LTE 124
Query: 391 YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
Y C+C G++ K +C + D C N C C SY C C + G TC
Sbjct: 125 YKCRCPPGWSGK---SCQQADPCASNP--CANGGQCLPFEASYICHCPPSFHGP--TCRQ 177
Query: 451 -VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
V+EC + C H C N G +RC C + +C
Sbjct: 178 DVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNC 215
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 103 bits (248), Expect = 2e-21
Identities = 59/155 (38%), Positives = 80/155 (51%), Gaps = 18/155 (11%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
CN G +CD N +N K C C G+ G + QDVDEC L + C +C+N
Sbjct: 381 CNEGSNCDTNP----VNGKAICTCPSGYTGPACS-QDVDECS----LGANPCEHAGKCIN 431
Query: 387 VVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+G + CQCL GYT C ++V+EC N C DA C + G + C C GYEG
Sbjct: 432 TLGSFECQCLQGYTGP---RCEIDVNECVSNP--CQNDATCLDQIGEFQCICMPGYEG-V 485
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+ ++ DEC S C H+ RC++ F+CEC T
Sbjct: 486 HCEVNTDEC--ASSPCLHNGRCLDKINEFQCECPT 518
Score = 96.3 bits (229), Expect = 3e-19
Identities = 78/282 (27%), Positives = 114/282 (40%), Gaps = 37/282 (13%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGEITC-RP-VECDRAECKNPVLHPGECCPT--CLR 259
C GT H + +++ C C H C RP V C + C+N G C PT
Sbjct: 189 CRHGGTCHNEVGSYR--CV-CRATHTGPNCERPYVPCSPSPCQNG----GTCRPTGDVTH 241
Query: 260 QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
+C +C C +G V+ C P +++ G+ C
Sbjct: 242 ECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNT------YNCRCPPEWT--GQYCT 293
Query: 320 FCPGVDYCN-MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC 378
VD C M ++C TC N + Y C C G+ G+ + +++D+C A HG C
Sbjct: 294 --EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS-ENIDDCASAACFHGATC 350
Query: 379 HSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP--GSYTCR 436
H V + C+C G T C D C N C+ + C P G C
Sbjct: 351 HDR------VASFYCECPHGRTG---LLCHLNDACISNP--CNEGSNCDTNPVNGKAICT 399
Query: 437 CRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C GY G + VDEC+ G++ C H+ +C+N G F C+C
Sbjct: 400 CPSGYTGPACS-QDVDECSLGANPCEHAGKCINTLGSFECQC 440
Score = 95.9 bits (228), Expect = 4e-19
Identities = 86/297 (28%), Positives = 122/297 (41%), Gaps = 44/297 (14%)
Query: 199 DC-QKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKN-PVLHPGECCPT 256
DC + SC++ GT DG + C C G T + D EC + P LH G C
Sbjct: 986 DCTESSCFNGGTC-VDGI----NSFTCLCPPG-FTGSYCQHDVNECDSQPCLHGGTCQDG 1039
Query: 257 C-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQC--TRVDPELACPR----LPCDPPQ 309
C +C + C C +G +C T CP L CD P
Sbjct: 1040 CGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG-KCWQTHTQYRCECPSGWTGLYCDVP- 1097
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQ 368
SV E GVD + C C++ + C+C G+ G C+D VDEC
Sbjct: 1098 --SVSCEVAAQRQGVDVARL---CQHGGLCVDAGNTHHCRCQAGYTGS--YCEDLVDECS 1150
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCT 427
+ C + C + +GGY C+C+ GY NC E+DEC +H C C
Sbjct: 1151 PSP------CQNGATCTDYLGGYSCKCVAGY---HGVNCSEEIDEC--LSHPCQNGGTCL 1199
Query: 428 NTPGSYTCRCRDGYEGDGYTCMHVDEC------TEGSHTCHHSARCVNIDGGFRCEC 478
+ P +Y C C G +G + ++VD+C S C ++ CV+ GG+ C C
Sbjct: 1200 DLPNTYKCSCPRGTQG-VHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC 1255
Score = 89.8 bits (213), Expect = 3e-17
Identities = 83/295 (28%), Positives = 121/295 (41%), Gaps = 43/295 (14%)
Query: 211 HADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEH 270
H + A CN S PV +A C P + G C + +C L N EH
Sbjct: 371 HLNDACISNPCNEGS----NCDTNPVN-GKAICTCPSGYTGPACSQDVDECSLGANPCEH 425
Query: 271 -GERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQ-FSVPGECCKFC-PGVD 325
G+ EC C G +C +D C PC GE C PG +
Sbjct: 426 AGKCINTLGSFECQCLQGYTGPRC-EIDVN-ECVSNPCQNDATCLDQIGEFQCICMPGYE 483
Query: 326 --YCNMGHS------CDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGH 376
+C + C N C++ ++ C+C GF G CQ DVDEC
Sbjct: 484 GVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGH--LCQYDVDECASTP----- 536
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTC 435
C + +C++ Y C C GYT +C V++DEC+ + CH + C + ++TC
Sbjct: 537 -CKNGAKCLDGPNTYTCVCTEGYTGT---HCEVDIDECDPDP--CHYGS-CKDGVATFTC 589
Query: 436 RCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT----ENCELS 486
CR GY G + +++EC+ S C H C + D + C C NCE++
Sbjct: 590 LCRPGYTGH-HCETNINECS--SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEIN 641
Score = 82.6 bits (195), Expect = 4e-15
Identities = 79/326 (24%), Positives = 123/326 (37%), Gaps = 43/326 (13%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGA-TWQRDCNR-CSCVHGEIT---CRPVECDRA 241
G + + + +C + NG DG T+ C + H E+ C P C
Sbjct: 519 GFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG 578
Query: 242 ECKNPVL---------HPGECCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDGNMQC 291
CK+ V + G C T + +C HG ++ A C C G
Sbjct: 579 SCKDGVATFTCLCRPGYTGHHCETNINECS--SQPCRHGGTCQDRDNAYLCFCLKGTTGP 636
Query: 292 TRVDPELACPRLPCDPPQQFS-VPGECCKFCPGV--DYCNM------GHSCDENATCMNL 342
C PCD + G C PG CN+ G+ C TC +
Sbjct: 637 NCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDG 696
Query: 343 NTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK 402
+TC+C +G+ D +V+EC +HG C + + GY C C G++
Sbjct: 697 INGFTCRCPEGYH-DPTCLSEVNECNSNPCVHG-------ACRDSLNGYKCDCDPGWSGT 748
Query: 403 DKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTC 461
NC + +ECE N C C + Y C CR+G+ G +++EC S+ C
Sbjct: 749 ---NCDINNNECESNP--CVNGGTCKDMTSGYVCTCREGFSGPNCQT-NINECA--SNPC 800
Query: 462 HHSARCVNIDGGFRCECFTENCELSC 487
+ C++ G++C C +C
Sbjct: 801 LNQGTCIDDVAGYKCNCLLPYTGATC 826
Score = 80.2 bits (189), Expect = 2e-14
Identities = 47/164 (28%), Positives = 73/164 (44%), Gaps = 13/164 (7%)
Query: 333 CDENATCMNL-NTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C TC + + C C GF G +++D+C G++C + CV+ V Y
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCE-ENIDDCP------GNNCKNGGACVDGVNTY 279
Query: 392 VCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHV 451
C+C +T ++ +VDEC+ + C C NT G Y C C +G+ G+ + ++
Sbjct: 280 NCRCPPEWT--GQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS-ENI 336
Query: 452 DECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
D+C S C H A C + F CEC L C +S
Sbjct: 337 DDC--ASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Score = 79.0 bits (186), Expect = 5e-14
Identities = 76/273 (27%), Positives = 107/273 (39%), Gaps = 35/273 (12%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPK-E 278
DC C G TC + D EC + G C + +C GN +G
Sbjct: 644 DCASSPCDSG--TCLD-KIDGYECACEPGYTGSMCNINIDECA--GNPCHNGGTCEDGIN 698
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCPGVDYCNM---GHSCD 334
C C +G T + C PC + S+ G C PG N + C+
Sbjct: 699 GFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECE 758
Query: 335 EN-----ATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVV 388
N TC ++ + Y C C +GF G CQ +++EC + C + C++ V
Sbjct: 759 SNPCVNGGTCKDMTSGYVCTCREGFSGP--NCQTNINECA------SNPCLNQGTCIDDV 810
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGDGY 446
GY C CL YT C EV C C + S++C C G++G
Sbjct: 811 AGYKCNCLLPYTGA---TC-EVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQ-- 864
Query: 447 TC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
TC + ++EC C H A C N GG+RC C
Sbjct: 865 TCEVDINECV--LSPCRHGASCQNTHGGYRCHC 895
Score = 79.0 bits (186), Expect = 5e-14
Identities = 75/287 (26%), Positives = 117/287 (40%), Gaps = 33/287 (11%)
Query: 198 CDCQKS-CYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP 255
CD + C SN V+ C+C G + + + EC NP L+ G C
Sbjct: 750 CDINNNECESNPCVNGGTCKDMTSGYVCTCREG-FSGPNCQTNINECASNPCLNQGTCID 808
Query: 256 TCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
CLL AP CA C +G +C + + + C P +
Sbjct: 809 DVAGYKCNCLLPYTGATCEVVLAP--CAPSPCRNGG-ECRQSEDYES---FSCVCPTGWQ 862
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAG 371
G+ C+ ++ C + C A+C N + Y C C G+ G C+ D+D+C+
Sbjct: 863 --GQTCEV--DINECVLS-PCRHGASCQNTHGGYRCHCQAGYSGRN--CETDIDDCRP-- 913
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+ CH+ C + + C CL G+ + F +++EC + C A CT+
Sbjct: 914 ----NPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVD 965
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SYTC C G+ G + + +CTE S C + CV+ F C C
Sbjct: 966 SYTCTCPAGFSGI-HCENNTPDCTESS--CFNGGTCVDGINSFTCLC 1009
Score = 78.6 bits (185), Expect = 6e-14
Identities = 53/164 (32%), Positives = 72/164 (43%), Gaps = 14/164 (8%)
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLH 374
GE C +D C +C ATC + + C+C G GL C D C
Sbjct: 329 GEDCS--ENIDDCASA-ACFHGATCHDRVASFYCECPHG--RTGLLCHLNDACISNPCNE 383
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYT 434
G +C +N V G +C C GYT +VDEC + C C NT GS+
Sbjct: 384 GSNCDTNP----VNGKAICTCPSGYTGPACSQ--DVDECSLGANPCEHAGKCINTLGSFE 437
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+C GY G + V+EC S+ C + A C++ G F+C C
Sbjct: 438 CQCLQGYTGPRCE-IDVNECV--SNPCQNDATCLDQIGEFQCIC 478
Score = 75.4 bits (177), Expect = 6e-13
Identities = 49/162 (30%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGG--LHGHHCHS 380
+D C + H C TC++L Y C C +G Q G+ C+ +VD+C C +
Sbjct: 1184 IDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQ--GVHCEINVDDCNPPVDPVSRSPKCFN 1240
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
N CV+ VGGY C C G+ + C +V+EC N C + C CR
Sbjct: 1241 NGTCVDQVGGYSCTCPPGFVGE---RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 1297
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCV---NIDGGFRCEC 478
G+ G C V +G C + C N GF C+C
Sbjct: 1298 GH--TGRRCESVINGCKGK-PCKNGGTCAVASNTARGFICKC 1336
Score = 68.9 bits (161), Expect = 5e-11
Identities = 78/300 (26%), Positives = 113/300 (37%), Gaps = 38/300 (12%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCL 258
DC+ + NG DG + C C+ G E D EC + G C C+
Sbjct: 910 DCRPNPCHNGGSCTDGI----NTAFCDCLPG-FRGTFCEEDINECASDPCRNGANCTDCV 964
Query: 259 RQ--CLLWGNLYE-HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPG 315
C H E P +C E C +G T VD C P F+ G
Sbjct: 965 DSYTCTCPAGFSGIHCENNTP-DCTESSCFNGG---TCVD---GINSFTCLCPPGFT--G 1015
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
C+ V+ C+ C TC + Y C C QG+ G CQ+ V C +
Sbjct: 1016 SYCQH--DVNECD-SQPCLHGGTCQDGCGSYRCTCPQGYTGPN--CQNLVHWCDSSP--- 1067
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRK----DKFNCVEVDECEGNTHG--CHADAVCTN 428
C + +C Y C+C G+T +C + +G C +C +
Sbjct: 1068 ---CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVD 1124
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
++ CRC+ GY G Y VDEC+ C + A C + GG+ C+C ++CS
Sbjct: 1125 AGNTHHCRCQAGYTGS-YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCS 1181
Score = 64.5 bits (150), Expect = 1e-09
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHS 380
P VD + C N TC++ Y+C C GF G+ C+ DV+EC +
Sbjct: 1227 PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE--RCEGDVNECLS----NPCDARG 1280
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCVEV-DECEGN-THGCHADAVCTNTPGSYTCRCR 438
CV V + C+C G+T + C V + C+G AV +NT + C+C
Sbjct: 1281 TQNCVQRVNDFHCECRAGHTGR---RCESVINGCKGKPCKNGGTCAVASNTARGFICKCP 1337
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+E G TC + D T GS C + C++ C C
Sbjct: 1338 AGFE--GATCEN-DARTCGSLRCLNGGTCISGPRSPTCLC 1374
Score = 59.3 bits (137), Expect = 4e-08
Identities = 54/218 (24%), Positives = 77/218 (35%), Gaps = 33/218 (15%)
Query: 291 CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-----CDENATCMNLNTK 345
C + P LA C P + + G C+ G + C G + C + C++ K
Sbjct: 10 CLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCK 69
Query: 346 ---------------YTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG 390
Y C C GF G + C +G C T +
Sbjct: 70 NAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLT-----LTE 124
Query: 391 YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
Y C+C G++ K +C + D C N C C SY C C + G TC
Sbjct: 125 YKCRCPPGWSGK---SCQQADPCASNP--CANGGQCLPFEASYICHCPPSFHGP--TCRQ 177
Query: 451 -VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
V+EC + C H C N G +RC C + +C
Sbjct: 178 DVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNC 215
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 103 bits (246), Expect = 3e-21
Identities = 99/346 (28%), Positives = 143/346 (41%), Gaps = 48/346 (13%)
Query: 172 QELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSN-----GT---VHAD---------- 213
Q +++ I+ L+ KLV E + L+Q +K C SN GT +H
Sbjct: 104 QNISSQIYQLNSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWK 163
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDRA-ECKNPVLHPGECCP--TCLRQCLLWGNLYEH 270
G D N C G P+ C C N + CP T QC + Y+
Sbjct: 164 GPLCSADVNECEIYSGT----PLSCQNGGTCVNTMGSYSCHCPPETYGPQC---ASKYDD 216
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG 330
E + C +C D M+ +P+ +C CD FS C D C+
Sbjct: 217 CEGGSVARCVHGICED-LMREQAGEPKYSCV---CDAGWMFSPNSPACTL--DRDECSFQ 270
Query: 331 HS-CDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
C C N + C C G+QG+G C+D++EC+ G G CVN
Sbjct: 271 PGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNG--GCSVAPPVECVNTP 328
Query: 389 GGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY-TCRCRDGYEGDGY 446
G CQ C GY + D C D C + GCH DA C++T GS C C GY G+GY
Sbjct: 329 GSSHCQACPPGY-QGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 387
Query: 447 ---TCMHVDE-CTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
C+ + C SH C + +C++ G+ C+C + ++C+
Sbjct: 388 GPNGCVQLSNICL--SHPC-LNGQCIDTVSGYFCKCDSGWTGVNCT 430
Score = 73.3 bits (172), Expect = 2e-12
Identities = 50/165 (30%), Positives = 73/165 (44%), Gaps = 16/165 (9%)
Query: 321 CPGVDYC---NMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLTCQDVDECQEAGGLHGH 376
C ++ C N G S C+N C+ C G+QGDG C D C + G
Sbjct: 303 CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNG---- 358
Query: 377 HCHSNTRCVNVVGGY-VCQCLGGYTRKD--KFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
CH + C + +G +C CL GYT CV++ +H C + C +T Y
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNI-CLSHPC-LNGQCIDTVSGY 416
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+C G+ G T +++EC S+ C + CV+ F CEC
Sbjct: 417 FCKCDSGWTGVNCT-ENINECL--SNPCLNGGTCVDGVDSFSCEC 458
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 103 bits (246), Expect = 3e-21
Identities = 99/346 (28%), Positives = 143/346 (41%), Gaps = 48/346 (13%)
Query: 172 QELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSN-----GT---VHAD---------- 213
Q +++ I+ L+ KLV E + L+Q +K C SN GT +H
Sbjct: 104 QNISSQIYQLNSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWK 163
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDRA-ECKNPVLHPGECCP--TCLRQCLLWGNLYEH 270
G D N C G P+ C C N + CP T QC + Y+
Sbjct: 164 GPLCSADVNECEIYSGT----PLSCQNGGTCVNTMGSYSCHCPPETYGPQC---ASKYDD 216
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG 330
E + C +C D M+ +P+ +C CD FS C D C+
Sbjct: 217 CEGGSVARCVHGICED-LMREQAGEPKYSCV---CDAGWMFSPNSPACTL--DRDECSFQ 270
Query: 331 HS-CDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
C C N + C C G+QG+G C+D++EC+ G G CVN
Sbjct: 271 PGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNG--GCSVAPPVECVNTP 328
Query: 389 GGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY-TCRCRDGYEGDGY 446
G CQ C GY + D C D C + GCH DA C++T GS C C GY G+GY
Sbjct: 329 GSSHCQACPPGY-QGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 387
Query: 447 ---TCMHVDE-CTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
C+ + C SH C + +C++ G+ C+C + ++C+
Sbjct: 388 GPNGCVQLSNICL--SHPC-LNGQCIDTVSGYFCKCDSGWTGVNCT 430
Score = 73.3 bits (172), Expect = 2e-12
Identities = 50/165 (30%), Positives = 73/165 (44%), Gaps = 16/165 (9%)
Query: 321 CPGVDYC---NMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLTCQDVDECQEAGGLHGH 376
C ++ C N G S C+N C+ C G+QGDG C D C + G
Sbjct: 303 CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNG---- 358
Query: 377 HCHSNTRCVNVVGGY-VCQCLGGYTRKD--KFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
CH + C + +G +C CL GYT CV++ +H C + C +T Y
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNI-CLSHPC-LNGQCIDTVSGY 416
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+C G+ G T +++EC S+ C + CV+ F CEC
Sbjct: 417 FCKCDSGWTGVNCT-ENINECL--SNPCLNGGTCVDGVDSFSCEC 458
>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 103 bits (246), Expect = 3e-21
Identities = 99/346 (28%), Positives = 143/346 (41%), Gaps = 48/346 (13%)
Query: 172 QELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSN-----GT---VHAD---------- 213
Q +++ I+ L+ KLV E + L+Q +K C SN GT +H
Sbjct: 104 QNISSQIYQLNSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGTCLNLHDSFFCICPPQWK 163
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDRA-ECKNPVLHPGECCP--TCLRQCLLWGNLYEH 270
G D N C G P+ C C N + CP T QC + Y+
Sbjct: 164 GPLCSADVNECEIYSGT----PLSCQNGGTCVNTMGSYSCHCPPETYGPQC---ASKYDD 216
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG 330
E + C +C D M+ +P+ +C CD FS C D C+
Sbjct: 217 CEGGSVARCVHGICED-LMREQAGEPKYSCV---CDAGWMFSPNSPACTL--DRDECSFQ 270
Query: 331 HS-CDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
C C N + C C G+QG+G C+D++EC+ G G CVN
Sbjct: 271 PGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNG--GCSVAPPVECVNTP 328
Query: 389 GGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY-TCRCRDGYEGDGY 446
G CQ C GY + D C D C + GCH DA C++T GS C C GY G+GY
Sbjct: 329 GSSHCQACPPGY-QGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 387
Query: 447 ---TCMHVDE-CTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
C+ + C SH C + +C++ G+ C+C + ++C+
Sbjct: 388 GPNGCVQLSNICL--SHPC-LNGQCIDTVSGYFCKCDSGWTGVNCT 430
Score = 73.3 bits (172), Expect = 2e-12
Identities = 50/165 (30%), Positives = 73/165 (44%), Gaps = 16/165 (9%)
Query: 321 CPGVDYC---NMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLTCQDVDECQEAGGLHGH 376
C ++ C N G S C+N C+ C G+QGDG C D C + G
Sbjct: 303 CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNG---- 358
Query: 377 HCHSNTRCVNVVGGY-VCQCLGGYTRKD--KFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
CH + C + +G +C CL GYT CV++ +H C + C +T Y
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNI-CLSHPC-LNGQCIDTVSGY 416
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+C G+ G T +++EC S+ C + CV+ F CEC
Sbjct: 417 FCKCDSGWTGVNCT-ENINECL--SNPCLNGGTCVDGVDSFSCEC 458
>AF054501-1|AAC39881.1| 161|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 161
Score = 103 bits (246), Expect = 3e-21
Identities = 60/150 (40%), Positives = 75/150 (50%), Gaps = 12/150 (8%)
Query: 335 ENATCMNLNTKYTCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
++ C N + + C C G + D +C DVDEC+E G C S RC N G Y
Sbjct: 3 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPAL---CGSQ-RCENSPGSYR 58
Query: 393 C--QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG--DGYTC 448
C C GY + C +VDEC N C A AVC N PGS+ C C GYEG DG C
Sbjct: 59 CVRDCDPGYHAGPEGTCDDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC 117
Query: 449 MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+ V+EC C +A C N++G F C C
Sbjct: 118 VDVNECETLQGVC-GAALCENVEGSFLCVC 146
Score = 69.7 bits (163), Expect = 3e-11
Identities = 51/157 (32%), Positives = 68/157 (43%), Gaps = 17/157 (10%)
Query: 291 CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN-MGHSCDENATCMNLNTKYTC- 348
CT D C C P + G C VD C G + + C N Y C
Sbjct: 7 CTNTDGSFECI---CPPGHR---AGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 60
Query: 349 -KCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT-RKDKF 405
C+ G+ G TC DVDEC+ C ++ C N+ G + C C GY +D
Sbjct: 61 RDCDPGYHAGPEGTCDDVDECRNRS-----FCGAHAVCQNLPGSFQCLCDQGYEGARDGR 115
Query: 406 NCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
+CV+V+ECE C A A+C N GS+ C C + E
Sbjct: 116 HCVDVNECETLQGVCGA-ALCENVEGSFLCVCPNSPE 151
Score = 64.1 bits (149), Expect = 1e-09
Identities = 37/111 (33%), Positives = 49/111 (44%), Gaps = 12/111 (10%)
Query: 287 GNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKY 346
G+ +C C R CDP G C VD C C +A C NL +
Sbjct: 46 GSQRCENSPGSYRCVR-DCDPGYHAGPEGTC----DDVDECRNRSFCGAHAVCQNLPGSF 100
Query: 347 TCKCNQGFQG--DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQC 395
C C+QG++G DG C DV+EC+ G+ G C NV G ++C C
Sbjct: 101 QCLCDQGYEGARDGRHCVDVNECETLQGVCG-----AALCENVEGSFLCVC 146
>BC053933-1|AAH53933.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 101 bits (243), Expect = 6e-21
Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C ++++C+N C+CN GF TC D++EC + C + C
Sbjct: 33 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVS---CGKFSDCW 86
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 147 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 191
Score = 93.1 bits (221), Expect = 3e-18
Identities = 48/123 (39%), Positives = 63/123 (51%), Gaps = 16/123 (13%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 78 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 133
Query: 382 TRCVNVVGGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ +D C +V+EC + CH+ C N GSY CRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 440 GYE 442
G++
Sbjct: 194 GWQ 196
>BC034949-1|AAH34949.1| 239|Homo sapiens EMR2 protein protein.
Length = 239
Score = 101 bits (243), Expect = 6e-21
Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 25/165 (15%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGL-------TCQDVDECQEAGGLHGHHCHSNTRCV 385
C ++++C+N C+CN GF TC D++EC + C + C
Sbjct: 33 CPQDSSCVNATA---CRCNPGFSSFSEIITTPMETCDDINECATLSKVS---CGKFSDCW 86
Query: 386 NVVGGYVCQCLGGYT---------RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCR 436
N G Y C C GY + + C +VDEC+ N C + C NT GSYTC+
Sbjct: 87 NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQ 146
Query: 437 CRDGYE---GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C G++ D C V+ECT G + CH S C+N G ++C C
Sbjct: 147 CLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRC 191
Score = 93.1 bits (221), Expect = 3e-18
Identities = 48/123 (39%), Positives = 63/123 (51%), Gaps = 16/123 (13%)
Query: 332 SCDENATCMNLNTKYTCKCNQGFQG-DGL---------TCQDVDECQEAGGLHGHHCHSN 381
SC + + C N Y C C+ G++ G TCQDVDECQ+ L C S
Sbjct: 78 SCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRL----CKSY 133
Query: 382 TRCVNVVGGYVCQCLGGYT--RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
CVN +G Y CQCL G+ +D C +V+EC + CH+ C N GSY CRCR
Sbjct: 134 GTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRP 193
Query: 440 GYE 442
G++
Sbjct: 194 GWQ 196
>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
receptor precursor protein.
Length = 3623
Score = 99 bits (238), Expect = 2e-20
Identities = 96/342 (28%), Positives = 142/342 (41%), Gaps = 40/342 (11%)
Query: 172 QELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCV---H 228
Q +++ I+ L+ KLV E + L+Q +K C SN + D C C
Sbjct: 104 QNISSQIYQLNSKLVDLERKFQGLQQTVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWK 163
Query: 229 GEITCRPV-ECD-----RAECKNP-----VLHPGEC-CP--TCLRQCLLWGNLYEHGERF 274
G + V EC+ C+N + C CP T QC + Y+ E
Sbjct: 164 GPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQC---ASKYDDCEGG 220
Query: 275 APKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-C 333
+ C +C D M+ +P+ +C CD S C D C+ C
Sbjct: 221 SVARCVHGICED-LMREQAGEPKYSCV---CDAGWMSSPNSPACTL--DRDECSFQPGPC 274
Query: 334 DENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C N + C C G+QG+G C+D++EC+ G G CVN G
Sbjct: 275 STLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNG--GCSVAPPVECVNTPGSSH 332
Query: 393 CQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY-TCRCRDGYEGDGY---T 447
CQ C GY + D C D C + GCH DA C++T GS C C GY G+GY
Sbjct: 333 CQACPPGY-QGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNG 391
Query: 448 CMHVDE-CTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
C+ + C SH C + +C++ G+ C+C + ++C+
Sbjct: 392 CVQLSNICL--SHPC-LNGQCIDTVSGYFCKCDSGWTGVNCT 430
Score = 73.3 bits (172), Expect = 2e-12
Identities = 50/165 (30%), Positives = 73/165 (44%), Gaps = 16/165 (9%)
Query: 321 CPGVDYC---NMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLTCQDVDECQEAGGLHGH 376
C ++ C N G S C+N C+ C G+QGDG C D C + G
Sbjct: 303 CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNG---- 358
Query: 377 HCHSNTRCVNVVGGY-VCQCLGGYTRKD--KFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
CH + C + +G +C CL GYT CV++ +H C + C +T Y
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNI-CLSHPC-LNGQCIDTVSGY 416
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+C G+ G T +++EC S+ C + CV+ F CEC
Sbjct: 417 FCKCDSGWTGVNCT-ENINECL--SNPCLNGGTCVDGVDSFSCEC 458
>AF054502-1|AAC39882.1| 669|Homo sapiens latent transforming growth
factor-beta binding protein 4 protein.
Length = 669
Score = 99.1 bits (236), Expect = 4e-20
Identities = 78/254 (30%), Positives = 104/254 (40%), Gaps = 24/254 (9%)
Query: 237 EC-DRAECKNPVLHPGECCPTCLR--QCLLW--GNLYEHGERFAPKECAECVCHDG-NMQ 290
EC D EC+N + PG+ C QC G+ G EC+ G +
Sbjct: 14 ECEDVDECENHLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGH 73
Query: 291 CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKC 350
CT + C C P + P C V+ C G C + C+N + + C C
Sbjct: 74 CTNTEGSFRCS---CAPG--YRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 128
Query: 351 NQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR-KDKFNC 407
G++ G +C DVDEC E C S C N G + C C G+ D +C
Sbjct: 129 APGYRPGPRGASCLDVDECSEED-----LCQSGI-CTNTDGSFECICPPGHRAGPDLASC 182
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTC--RCRDGYE-GDGYTCMHVDECTEGSHTCHHS 464
++VDEC C N+PGSY C C GY G TC V+EC C +
Sbjct: 183 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVC-GA 241
Query: 465 ARCVNIDGGFRCEC 478
A C N++G F C C
Sbjct: 242 ALCENVEGSFLCVC 255
Score = 87.0 bits (206), Expect = 2e-16
Identities = 47/131 (35%), Positives = 57/131 (43%), Gaps = 12/131 (9%)
Query: 353 GFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEV 410
GFQ + G C+DVDEC+ H CVN G + C+ + C +V
Sbjct: 5 GFQPNAAGSECEDVDECEN------HLACPGQECVNSPGSFQCRACPSGHHLHRGRCTDV 58
Query: 411 DECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EGDGYTCMHVDECTEGSHTCHHSARC 467
DEC C CTNT GS+ C C GY G C V+EC EG C C
Sbjct: 59 DECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDF-CFPHGEC 117
Query: 468 VNIDGGFRCEC 478
+N DG F C C
Sbjct: 118 LNTDGSFACTC 128
Score = 75.8 bits (178), Expect = 5e-13
Identities = 75/261 (28%), Positives = 103/261 (39%), Gaps = 31/261 (11%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHP-GEC 253
+++C+ +C V++ G+ C C H R + D P P G C
Sbjct: 18 VDECENHLACPGQECVNSPGSF---QCRACPSGHHLHRGRCTDVDECSSGAPPCGPHGHC 74
Query: 254 CPT--CLRQCLLWGNLYEHGERFAPKECAEC-VCHDGNM-----QCTRVDPELACPRLPC 305
T R G G P CA+ C +G+ +C D AC C
Sbjct: 75 TNTEGSFRCSCAPGYRAPSGR---PGPCADVNECLEGDFCFPHGECLNTDGSFACT---C 128
Query: 306 DPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG--DGLTCQD 363
P + PG C VD C+ C ++ C N + + C C G + D +C D
Sbjct: 129 APGYR---PGPRGASCLDVDECSEEDLC-QSGICTNTDGSFECICPPGHRAGPDLASCLD 184
Query: 364 VDECQEAGGLHGHHCHSNTRCVNVVGGYVC--QCLGGYTRKDKFNCVEVDECEGNTHGCH 421
VDEC+E G C S RC N G Y C C GY + C +V+ECE C
Sbjct: 185 VDECRERGPAL---CGSQ-RCENSPGSYRCVRDCDPGYHAGPEGTCDDVNECETLQGVCG 240
Query: 422 ADAVCTNTPGSYTCRCRDGYE 442
A A+C N GS+ C C + E
Sbjct: 241 A-ALCENVEGSFLCVCPNSPE 260
Score = 58.4 bits (135), Expect = 7e-08
Identities = 34/91 (37%), Positives = 38/91 (41%), Gaps = 6/91 (6%)
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG-YTRKDKFNCVEVDECE 414
GD +DVDECQ C S CVN GY C C G Y + C++ DEC
Sbjct: 383 GDLSLRRDVDECQL---FRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDNDECA 438
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
C C NT GSY C C DG
Sbjct: 439 DEEPACEGGR-CVNTVGSYHCTCEPPLVLDG 468
Score = 52.0 bits (119), Expect = 6e-06
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Query: 409 EVDECEGNTHGCHADAVCTNTPGSYTCRCRDG--YEGDGYTCMHVDECTEGSHTCHHSAR 466
+VDEC+ VC NT Y+C C +G Y C+ DEC + C R
Sbjct: 390 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPAC-EGGR 448
Query: 467 CVNIDGGFRCEC 478
CVN G + C C
Sbjct: 449 CVNTVGSYHCTC 460
Score = 41.5 bits (93), Expect = 0.009
Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 10/76 (13%)
Query: 324 VDYCNMGHS--CDENATCMNLNTKYTCKCNQG--FQGDGLTCQDVDECQEAGGLHGHHCH 379
VD C + C ++ C+N Y+C C+ G + L C D DEC + C
Sbjct: 391 VDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD----EEPACE 445
Query: 380 SNTRCVNVVGGYVCQC 395
RCVN VG Y C C
Sbjct: 446 GG-RCVNTVGSYHCTC 460
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 98.7 bits (235), Expect = 6e-20
Identities = 57/164 (34%), Positives = 76/164 (46%), Gaps = 17/164 (10%)
Query: 319 KFCP-GVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
+FC VD C + ++C TC N ++C C G+ G+ + Q++D+C A HG
Sbjct: 269 QFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS-QNIDDCATAVCFHGA 327
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP--GSYT 434
CH V + C C G K C D C N CH DA+C P G
Sbjct: 328 TCHDR------VASFYCACPMG---KTGLLCHLDDACVSNP--CHEDAICDTNPVNGRAI 376
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C C G+ G G VDEC+ G++ C H RCVN G F C+C
Sbjct: 377 CTCPPGFTG-GACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 419
Score = 87.0 bits (206), Expect = 2e-16
Identities = 52/165 (31%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 333 CDENATCMNL-NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C TC + Y C C GF+G C+ +VD+C GH C + CV+ V
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQN--CEVNVDDCP------GHRCLNGGTCVDGVNT 257
Query: 391 YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
Y CQC +T +F +VDEC+ + CH C NT G ++C C +G+ G+ + +
Sbjct: 258 YNCQCPPEWT--GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS-QN 314
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
+D+C C H A C + F C C L C VS
Sbjct: 315 IDDCATA--VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS 357
Score = 87.0 bits (206), Expect = 2e-16
Identities = 81/273 (29%), Positives = 112/273 (41%), Gaps = 30/273 (10%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGER-FAPKE 278
DC C++G V +C P G+ C + +C L N +G F
Sbjct: 239 DCPGHRCLNGGTCVDGVNTYNCQC--PPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLG 296
Query: 279 CAECVCHDG--NMQCTRVDPELACP----RLPC-DPPQQF--SVP-GECCKFCPGVDYCN 328
CVC +G C++ + A C D F + P G+ C D C
Sbjct: 297 GHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDAC- 355
Query: 329 MGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + C E+A C +N + C C GF G G QDVDEC + + C RCVN
Sbjct: 356 VSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECS----IGANPCEHLGRCVN 410
Query: 387 VVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
G ++CQC GYT C +V+EC C A C + G +TC C G+ G
Sbjct: 411 TQGSFLCQCGRGYTGP---RCETDVNECLSGP--CRNQATCLDRIGQFTCICMAGFTGT- 464
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
Y + +DEC S C + C + GF C C
Sbjct: 465 YCEVDIDECQ--SSPCVNGGVCKDRVNGFSCTC 495
Score = 85.8 bits (203), Expect = 4e-16
Identities = 54/157 (34%), Positives = 76/157 (48%), Gaps = 20/157 (12%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNT 382
V+ C G C ATC++ ++TC C GF G C+ D+DECQ + ++G C
Sbjct: 432 VNECLSG-PCRNQATCLDRIGQFTCICMAGFTGT--YCEVDIDECQSSPCVNGGVCKDR- 487
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
V G+ C C G++ C ++VDEC C A C + P Y CRC +G+
Sbjct: 488 -----VNGFSCTCPSGFSGS---TCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGF 537
Query: 442 EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
EG +VD+C+ CHH RCV+ F C C
Sbjct: 538 EGT-LCDRNVDDCS--PDPCHH-GRCVDGIASFSCAC 570
Score = 84.6 bits (200), Expect = 1e-15
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 22/214 (10%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P C C G D C C P Q G C+ VD C +G C
Sbjct: 120 PDPCLSSPCAHGARCSVGPDGRFLCS---CPPGYQ----GRSCR--SDVDECRVGEPCRH 170
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQC 395
TC+N + C+C G+ G L C + +G C + Y C C
Sbjct: 171 GGTCLNTPGSFRCQCPAGYTGP-LCENPAVPCAPSPCRNGGTCRQSGDLT-----YDCAC 224
Query: 396 LGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
L G+ + NC V VD+C G H C C + +Y C+C + G + VDEC
Sbjct: 225 LPGFEGQ---NCEVNVDDCPG--HRCLNGGTCVDGVNTYNCQCPPEWTGQ-FCTEDVDEC 278
Query: 455 TEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
+ CH+ C N GG C C SCS
Sbjct: 279 QLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 312
Score = 81.4 bits (192), Expect = 9e-15
Identities = 79/277 (28%), Positives = 114/277 (41%), Gaps = 37/277 (13%)
Query: 228 HGEITC--RPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEH-GERFAPKECAECVC 284
H + C PV RA C P G C + +C + N EH G + C C
Sbjct: 361 HEDAICDTNPVN-GRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 419
Query: 285 HDG--NMQC-TRVDPELACP---RLPC-DPPQQFS---VPGECCKFCP-GVDYCNMGHSC 333
G +C T V+ L+ P + C D QF+ + G +C +D C C
Sbjct: 420 GRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSS-PC 478
Query: 334 DENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C + ++C C GF G TCQ DVDEC C + +CV+ GY
Sbjct: 479 VNGGVCKDRVNGFSCTCPSGFSGS--TCQLDVDECASTP------CRNGAKCVDQPDGYE 530
Query: 393 CQCLGGY--TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
C+C G+ T D+ VD+C + CH C + S++C C GY G
Sbjct: 531 CRCAEGFEGTLCDR----NVDDCSPDP--CHHGR-CVDGIASFSCACAPGYTGTRCESQ- 582
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
VDEC S C H +C+++ + C C + ++C
Sbjct: 583 VDECR--SQPCRHGGKCLDLVDKYLCRCPSGTTGVNC 617
Score = 76.2 bits (179), Expect = 3e-13
Identities = 79/270 (29%), Positives = 106/270 (39%), Gaps = 34/270 (12%)
Query: 250 PGECCPTCLRQCLLWGNL-YEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCD 306
PG P CL + HG + CVC G +C++ AC PC
Sbjct: 685 PGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCR 744
Query: 307 PPQQFSVPGEC--CKFCPGVD--YCNM-----GHSCDENATCMNLNTKY-TCKCNQGFQG 356
S G C PGV C + + C+ C + + C C QG+QG
Sbjct: 745 AGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQG 804
Query: 357 DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEG 415
QDVDEC AG C + C N+ G + C C GGYT +C ++++C+
Sbjct: 805 PRCQ-QDVDEC--AGPAP---CGPHGICTNLAGSFSCTCHGGYTGP---SCDQDINDCDP 855
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTE---GSHTC-HHSAR----C 467
N C C + GS++C C G+ G VDEC G TC H A C
Sbjct: 856 NP--CLNGGSCQDGVGSFSCSCLPGFAGPR-CARDVDECLSNPCGPGTCTDHVASFTCTC 912
Query: 468 VNIDGGFRCECFTENCELSCSWQGRVVSEG 497
GGF CE +C S + G +G
Sbjct: 913 PPGYGGFHCEQDLPDCSPSSCFNGGTCVDG 942
Score = 74.9 bits (176), Expect = 8e-13
Identities = 66/218 (30%), Positives = 90/218 (41%), Gaps = 31/218 (14%)
Query: 282 CVCHDGNM--QCTR-VDPELACPRLPCDPPQQFSVPGECCKFCPG---------VDYCNM 329
CVC +G C + VDP LA P + + + G C+ PG VD C
Sbjct: 1070 CVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGY-MGGYMCECLPGYNGDNCEDDVDEC-A 1127
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLH-GHHCHSNTRCVNV 387
C +C++L +Y C C G G + C+ + D+C L G C N CV++
Sbjct: 1128 SQPCQHGGSCIDLVARYLCSCPPGTLG--VLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1185
Query: 388 VGGYVCQCLGGYTRKDKFNC-VEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
VGG+ C C GYT C +++EC G H H + G + C C G+ G
Sbjct: 1186 VGGFRCTCPPGYT---GLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGP- 1241
Query: 446 YTCMHVDECTEGSHTCHHSARC---VNIDGG--FRCEC 478
C V E S C H +C GG F C C
Sbjct: 1242 -RCQTVLSPCE-SQPCQHGGQCRPSPGPGGGLTFTCHC 1277
Score = 73.7 bits (173), Expect = 2e-12
Identities = 86/296 (29%), Positives = 111/296 (37%), Gaps = 43/296 (14%)
Query: 223 RCSCVHGEITCRPVECDRA-ECKNPVLHPGECCPTCL--RQCLLWG----NLYEHGERF- 274
RCS C C C + + CP + RQC L N EHG R
Sbjct: 728 RCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCE 787
Query: 275 -APKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGV---DYC 327
AP + C C G +C + E A P PC P + + G C G C
Sbjct: 788 SAPGQLPVCSCPQGWQGPRCQQDVDECAGPA-PCGPHGICTNLAGSFSCTCHGGYTGPSC 846
Query: 328 NMG-HSCDEN-----ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN 381
+ + CD N +C + ++C C GF G +DVDEC + C
Sbjct: 847 DQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCA-RDVDECLS------NPCGPG 899
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C + V + C C GY F+C E D + + C C + S++C CR GY
Sbjct: 900 T-CTDHVASFTCTCPPGY---GGFHC-EQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 954
Query: 442 EGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCEC---FT-ENCELSCSWQGR 492
G C H D C S C H C GFRC C FT C+ W R
Sbjct: 955 --TGAHCQHEADPCL--SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSR 1006
Score = 69.3 bits (162), Expect = 4e-11
Identities = 72/275 (26%), Positives = 98/275 (35%), Gaps = 38/275 (13%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTC---LRQCLLWGNLYEHGERFAP 276
DC C G CR +R +C V PG P C + +C E G
Sbjct: 623 DCASNPCTFG--VCRD-GINRYDC---VCQPGFTGPLCNVEINECAS-SPCGEGGSCVDG 675
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFC-PGV----------- 324
+ C+C G++ + P C PC + PG C PG
Sbjct: 676 ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLAR 735
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
D C C TC + + C C G QG C+ + C HG C S
Sbjct: 736 DACE-SQPCRAGGTCSSDGMGFHCTCPPGVQGR--QCELLSPCTPNPCEHGGRCESAPGQ 792
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
+ V C C G+ C + VDEC G C +CTN GS++C C GY G
Sbjct: 793 LPV-----CSCPQGWQGP---RCQQDVDECAGPAP-CGPHGICTNLAGSFSCTCHGGYTG 843
Query: 444 DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+++C + C + C + G F C C
Sbjct: 844 PSCD-QDINDC--DPNPCLNGGSCQDGVGSFSCSC 875
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 17/149 (11%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNL----NTKYTCKCNQGFQ 355
C +LP PG + C D C+ G C C + +++C+C +GF+
Sbjct: 55 CTQLPSREAACLCPPGWVGERCQLEDPCHSG-PCAGRGVCQSSVVAGTARFSCRCPRGFR 113
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECE 414
G C D C + HG C V G ++C C GY + +C +VDEC
Sbjct: 114 GP--DCSLPDPCLSSPCAHGARC-----SVGPDGRFLCSCPPGYQGR---SCRSDVDECR 163
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C NTPGS+ C+C GY G
Sbjct: 164 VG-EPCRHGGTCLNTPGSFRCQCPAGYTG 191
Score = 56.4 bits (130), Expect = 3e-07
Identities = 69/276 (25%), Positives = 101/276 (36%), Gaps = 44/276 (15%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPK-E 278
+C CV+G + C+ + C P G C + +C +G + + +
Sbjct: 472 ECQSSPCVNGGV-CKD-RVNGFSCTCPSGFSGSTCQLDVDECA--STPCRNGAKCVDQPD 527
Query: 279 CAECVCHDGNMQCTRVDPELA-CPRLPC------DPPQQFS---VPGECCKFCPG-VDYC 327
EC C +G + T D + C PC D FS PG C VD C
Sbjct: 528 GYECRCAEG-FEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDEC 586
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVN 386
C C++L KY C+C G G+ C+ ++D+C + C C +
Sbjct: 587 R-SQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDCA------SNPCTFGV-CRD 636
Query: 387 VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ Y C C G+T VE++EC + C C + + C C G
Sbjct: 637 GINRYDCVCQPGFT--GPLCNVEINECASSP--CGEGGSCVDGENGFRCLCPPG------ 686
Query: 447 TCMHVDECTEGSHTCHHS----ARCVNIDGGFRCEC 478
C SH C H C + GGFRC C
Sbjct: 687 --SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVC 720
Score = 52.4 bits (120), Expect = 5e-06
Identities = 77/299 (25%), Positives = 101/299 (33%), Gaps = 43/299 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCL 258
DC + NG DG CSC+ G R D EC + PG C
Sbjct: 852 DCDPNPCLNGGSCQDGV----GSFSCSCLPGFAGPRCAR-DVDECLSNPCGPGTCTDHVA 906
Query: 259 RQCLLWGNLYE--HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGE 316
Y H E+ P +C+ C +G C +C C P G
Sbjct: 907 SFTCTCPPGYGGFHCEQDLP-DCSPSSCFNGGT-CVDGVNSFSCL---CRP----GYTGA 957
Query: 317 CCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHG 375
C+ D C + C C + + C C + F G CQ VD C
Sbjct: 958 HCQH--EADPC-LSRPCLHGGVCSAAHPGFRCTCLESFTGP--QCQTLVDWCSR------ 1006
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYTRK----DKFNCVEVDECEGNT--HGCHADAVCTNT 429
C + RCV G Y C C G++ + C E G C A C +
Sbjct: 1007 QPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDE 1064
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT----ENCE 484
S+ C C +G G + VD C + C H C GG+ CEC +NCE
Sbjct: 1065 DSSHYCVCPEGRTG-SHCEQEVDPCL--AQPCQHGGTCRGYMGGYMCECLPGYNGDNCE 1120
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 98.7 bits (235), Expect = 6e-20
Identities = 57/164 (34%), Positives = 76/164 (46%), Gaps = 17/164 (10%)
Query: 319 KFCP-GVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
+FC VD C + ++C TC N ++C C G+ G+ + Q++D+C A HG
Sbjct: 269 QFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS-QNIDDCATAVCFHGA 327
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP--GSYT 434
CH V + C C G K C D C N CH DA+C P G
Sbjct: 328 TCHDR------VASFYCACPMG---KTGLLCHLDDACVSNP--CHEDAICDTNPVNGRAI 376
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C C G+ G G VDEC+ G++ C H RCVN G F C+C
Sbjct: 377 CTCPPGFTG-GACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 419
Score = 87.0 bits (206), Expect = 2e-16
Identities = 52/165 (31%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 333 CDENATCMNL-NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C TC + Y C C GF+G C+ +VD+C GH C + CV+ V
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQN--CEVNVDDCP------GHRCLNGGTCVDGVNT 257
Query: 391 YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
Y CQC +T +F +VDEC+ + CH C NT G ++C C +G+ G+ + +
Sbjct: 258 YNCQCPPEWT--GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS-QN 314
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
+D+C C H A C + F C C L C VS
Sbjct: 315 IDDCATA--VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS 357
Score = 87.0 bits (206), Expect = 2e-16
Identities = 81/273 (29%), Positives = 112/273 (41%), Gaps = 30/273 (10%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGER-FAPKE 278
DC C++G V +C P G+ C + +C L N +G F
Sbjct: 239 DCPGHRCLNGGTCVDGVNTYNCQC--PPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLG 296
Query: 279 CAECVCHDG--NMQCTRVDPELACP----RLPC-DPPQQF--SVP-GECCKFCPGVDYCN 328
CVC +G C++ + A C D F + P G+ C D C
Sbjct: 297 GHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDAC- 355
Query: 329 MGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + C E+A C +N + C C GF G G QDVDEC + + C RCVN
Sbjct: 356 VSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECS----IGANPCEHLGRCVN 410
Query: 387 VVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
G ++CQC GYT C +V+EC C A C + G +TC C G+ G
Sbjct: 411 TQGSFLCQCGRGYTGP---RCETDVNECLSGP--CRNQATCLDRIGQFTCICMAGFTGT- 464
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
Y + +DEC S C + C + GF C C
Sbjct: 465 YCEVDIDECQ--SSPCVNGGVCKDRVNGFSCTC 495
Score = 85.8 bits (203), Expect = 4e-16
Identities = 54/157 (34%), Positives = 76/157 (48%), Gaps = 20/157 (12%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNT 382
V+ C G C ATC++ ++TC C GF G C+ D+DECQ + ++G C
Sbjct: 432 VNECLSG-PCRNQATCLDRIGQFTCICMAGFTGT--YCEVDIDECQSSPCVNGGVCKDR- 487
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
V G+ C C G++ C ++VDEC C A C + P Y CRC +G+
Sbjct: 488 -----VNGFSCTCPSGFSGS---TCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGF 537
Query: 442 EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
EG +VD+C+ CHH RCV+ F C C
Sbjct: 538 EGT-LCDRNVDDCS--PDPCHH-GRCVDGIASFSCAC 570
Score = 84.6 bits (200), Expect = 1e-15
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 22/214 (10%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P C C G D C C P Q G C+ VD C +G C
Sbjct: 120 PDPCLSSPCAHGARCSVGPDGRFLCS---CPPGYQ----GRSCR--SDVDECRVGEPCRH 170
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQC 395
TC+N + C+C G+ G L C + +G C + Y C C
Sbjct: 171 GGTCLNTPGSFRCQCPAGYTGP-LCENPAVPCAPSPCRNGGTCRQSGDLT-----YDCAC 224
Query: 396 LGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
L G+ + NC V VD+C G H C C + +Y C+C + G + VDEC
Sbjct: 225 LPGFEGQ---NCEVNVDDCPG--HRCLNGGTCVDGVNTYNCQCPPEWTGQ-FCTEDVDEC 278
Query: 455 TEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
+ CH+ C N GG C C SCS
Sbjct: 279 QLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 312
Score = 81.4 bits (192), Expect = 9e-15
Identities = 79/277 (28%), Positives = 114/277 (41%), Gaps = 37/277 (13%)
Query: 228 HGEITC--RPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEH-GERFAPKECAECVC 284
H + C PV RA C P G C + +C + N EH G + C C
Sbjct: 361 HEDAICDTNPVN-GRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 419
Query: 285 HDG--NMQC-TRVDPELACP---RLPC-DPPQQFS---VPGECCKFCP-GVDYCNMGHSC 333
G +C T V+ L+ P + C D QF+ + G +C +D C C
Sbjct: 420 GRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSS-PC 478
Query: 334 DENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C + ++C C GF G TCQ DVDEC C + +CV+ GY
Sbjct: 479 VNGGVCKDRVNGFSCTCPSGFSGS--TCQLDVDECASTP------CRNGAKCVDQPDGYE 530
Query: 393 CQCLGGY--TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
C+C G+ T D+ VD+C + CH C + S++C C GY G
Sbjct: 531 CRCAEGFEGTLCDR----NVDDCSPDP--CHHGR-CVDGIASFSCACAPGYTGTRCESQ- 582
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
VDEC S C H +C+++ + C C + ++C
Sbjct: 583 VDECR--SQPCRHGGKCLDLVDKYLCRCPSGTTGVNC 617
Score = 76.2 bits (179), Expect = 3e-13
Identities = 79/270 (29%), Positives = 106/270 (39%), Gaps = 34/270 (12%)
Query: 250 PGECCPTCLRQCLLWGNL-YEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCD 306
PG P CL + HG + CVC G +C++ AC PC
Sbjct: 685 PGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCR 744
Query: 307 PPQQFSVPGEC--CKFCPGVD--YCNM-----GHSCDENATCMNLNTKY-TCKCNQGFQG 356
S G C PGV C + + C+ C + + C C QG+QG
Sbjct: 745 AGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQG 804
Query: 357 DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEG 415
QDVDEC AG C + C N+ G + C C GGYT +C ++++C+
Sbjct: 805 PRCQ-QDVDEC--AGPAP---CGPHGICTNLAGSFSCTCHGGYTGP---SCDQDINDCDP 855
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTE---GSHTC-HHSAR----C 467
N C C + GS++C C G+ G VDEC G TC H A C
Sbjct: 856 NP--CLNGGSCQDGVGSFSCSCLPGFAGPR-CARDVDECLSNPCGPGTCTDHVASFTCTC 912
Query: 468 VNIDGGFRCECFTENCELSCSWQGRVVSEG 497
GGF CE +C S + G +G
Sbjct: 913 PPGYGGFHCEQDLPDCSPSSCFNGGTCVDG 942
Score = 74.9 bits (176), Expect = 8e-13
Identities = 66/218 (30%), Positives = 90/218 (41%), Gaps = 31/218 (14%)
Query: 282 CVCHDGNM--QCTR-VDPELACPRLPCDPPQQFSVPGECCKFCPG---------VDYCNM 329
CVC +G C + VDP LA P + + + G C+ PG VD C
Sbjct: 1070 CVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGY-MGGYMCECLPGYNGDNCEDDVDEC-A 1127
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLH-GHHCHSNTRCVNV 387
C +C++L +Y C C G G + C+ + D+C L G C N CV++
Sbjct: 1128 SQPCQHGGSCIDLVARYLCSCPPGTLG--VLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1185
Query: 388 VGGYVCQCLGGYTRKDKFNC-VEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
VGG+ C C GYT C +++EC G H H + G + C C G+ G
Sbjct: 1186 VGGFRCTCPPGYT---GLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGP- 1241
Query: 446 YTCMHVDECTEGSHTCHHSARC---VNIDGG--FRCEC 478
C V E S C H +C GG F C C
Sbjct: 1242 -RCQTVLSPCE-SQPCQHGGQCRPSPGPGGGLTFTCHC 1277
Score = 73.7 bits (173), Expect = 2e-12
Identities = 86/296 (29%), Positives = 111/296 (37%), Gaps = 43/296 (14%)
Query: 223 RCSCVHGEITCRPVECDRA-ECKNPVLHPGECCPTCL--RQCLLWG----NLYEHGERF- 274
RCS C C C + + CP + RQC L N EHG R
Sbjct: 728 RCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCE 787
Query: 275 -APKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGV---DYC 327
AP + C C G +C + E A P PC P + + G C G C
Sbjct: 788 SAPGQLPVCSCPQGWQGPRCQQDVDECAGPA-PCGPHGICTNLAGSFSCTCHGGYTGPSC 846
Query: 328 NMG-HSCDEN-----ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN 381
+ + CD N +C + ++C C GF G +DVDEC + C
Sbjct: 847 DQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCA-RDVDECLS------NPCGPG 899
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C + V + C C GY F+C E D + + C C + S++C CR GY
Sbjct: 900 T-CTDHVASFTCTCPPGY---GGFHC-EQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 954
Query: 442 EGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCEC---FT-ENCELSCSWQGR 492
G C H D C S C H C GFRC C FT C+ W R
Sbjct: 955 --TGAHCQHEADPCL--SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSR 1006
Score = 69.3 bits (162), Expect = 4e-11
Identities = 72/275 (26%), Positives = 98/275 (35%), Gaps = 38/275 (13%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTC---LRQCLLWGNLYEHGERFAP 276
DC C G CR +R +C V PG P C + +C E G
Sbjct: 623 DCASNPCTFG--VCRD-GINRYDC---VCQPGFTGPLCNVEINECAS-SPCGEGGSCVDG 675
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFC-PGV----------- 324
+ C+C G++ + P C PC + PG C PG
Sbjct: 676 ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLAR 735
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
D C C TC + + C C G QG C+ + C HG C S
Sbjct: 736 DACE-SQPCRAGGTCSSDGMGFHCTCPPGVQGR--QCELLSPCTPNPCEHGGRCESAPGQ 792
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
+ V C C G+ C + VDEC G C +CTN GS++C C GY G
Sbjct: 793 LPV-----CSCPQGWQGP---RCQQDVDECAGPAP-CGPHGICTNLAGSFSCTCHGGYTG 843
Query: 444 DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+++C + C + C + G F C C
Sbjct: 844 PSCD-QDINDC--DPNPCLNGGSCQDGVGSFSCSC 875
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 17/149 (11%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNL----NTKYTCKCNQGFQ 355
C +LP PG + C D C+ G C C + +++C+C +GF+
Sbjct: 55 CTQLPSREAACLCPPGWVGERCQLEDPCHSG-PCAGRGVCQSSVVAGTARFSCRCPRGFR 113
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECE 414
G C D C + HG C V G ++C C GY + +C +VDEC
Sbjct: 114 GP--DCSLPDPCLSSPCAHGARC-----SVGPDGRFLCSCPPGYQGR---SCRSDVDECR 163
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C NTPGS+ C+C GY G
Sbjct: 164 VG-EPCRHGGTCLNTPGSFRCQCPAGYTG 191
Score = 56.4 bits (130), Expect = 3e-07
Identities = 69/276 (25%), Positives = 101/276 (36%), Gaps = 44/276 (15%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPK-E 278
+C CV+G + C+ + C P G C + +C +G + + +
Sbjct: 472 ECQSSPCVNGGV-CKD-RVNGFSCTCPSGFSGSTCQLDVDECA--STPCRNGAKCVDQPD 527
Query: 279 CAECVCHDGNMQCTRVDPELA-CPRLPC------DPPQQFS---VPGECCKFCPG-VDYC 327
EC C +G + T D + C PC D FS PG C VD C
Sbjct: 528 GYECRCAEG-FEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDEC 586
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVN 386
C C++L KY C+C G G+ C+ ++D+C + C C +
Sbjct: 587 R-SQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDCA------SNPCTFGV-CRD 636
Query: 387 VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ Y C C G+T VE++EC + C C + + C C G
Sbjct: 637 GINRYDCVCQPGFT--GPLCNVEINECASSP--CGEGGSCVDGENGFRCLCPPG------ 686
Query: 447 TCMHVDECTEGSHTCHHS----ARCVNIDGGFRCEC 478
C SH C H C + GGFRC C
Sbjct: 687 --SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVC 720
Score = 52.4 bits (120), Expect = 5e-06
Identities = 77/299 (25%), Positives = 101/299 (33%), Gaps = 43/299 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCL 258
DC + NG DG CSC+ G R D EC + PG C
Sbjct: 852 DCDPNPCLNGGSCQDGV----GSFSCSCLPGFAGPRCAR-DVDECLSNPCGPGTCTDHVA 906
Query: 259 RQCLLWGNLYE--HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGE 316
Y H E+ P +C+ C +G C +C C P G
Sbjct: 907 SFTCTCPPGYGGFHCEQDLP-DCSPSSCFNGGT-CVDGVNSFSCL---CRP----GYTGA 957
Query: 317 CCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHG 375
C+ D C + C C + + C C + F G CQ VD C
Sbjct: 958 HCQH--EADPC-LSRPCLHGGVCSAAHPGFRCTCLESFTGP--QCQTLVDWCSR------ 1006
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYTRK----DKFNCVEVDECEGNT--HGCHADAVCTNT 429
C + RCV G Y C C G++ + C E G C A C +
Sbjct: 1007 QPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDE 1064
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT----ENCE 484
S+ C C +G G + VD C + C H C GG+ CEC +NCE
Sbjct: 1065 DSSHYCVCPEGRTG-SHCEQEVDPCL--AQPCQHGGTCRGYMGGYMCECLPGYNGDNCE 1120
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 98.7 bits (235), Expect = 6e-20
Identities = 57/164 (34%), Positives = 76/164 (46%), Gaps = 17/164 (10%)
Query: 319 KFCP-GVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
+FC VD C + ++C TC N ++C C G+ G+ + Q++D+C A HG
Sbjct: 229 QFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS-QNIDDCATAVCFHGA 287
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP--GSYT 434
CH V + C C G K C D C N CH DA+C P G
Sbjct: 288 TCHDR------VASFYCACPMG---KTGLLCHLDDACVSNP--CHEDAICDTNPVNGRAI 336
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C C G+ G G VDEC+ G++ C H RCVN G F C+C
Sbjct: 337 CTCPPGFTG-GACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 379
Score = 87.0 bits (206), Expect = 2e-16
Identities = 52/165 (31%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 333 CDENATCMNL-NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C TC + Y C C GF+G C+ +VD+C GH C + CV+ V
Sbjct: 166 CRNGGTCRQSGDLTYDCACLPGFEGQN--CEVNVDDCP------GHRCLNGGTCVDGVNT 217
Query: 391 YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
Y CQC +T +F +VDEC+ + CH C NT G ++C C +G+ G+ + +
Sbjct: 218 YNCQCPPEWT--GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS-QN 274
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
+D+C C H A C + F C C L C VS
Sbjct: 275 IDDCATA--VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS 317
Score = 87.0 bits (206), Expect = 2e-16
Identities = 81/273 (29%), Positives = 112/273 (41%), Gaps = 30/273 (10%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGER-FAPKE 278
DC C++G V +C P G+ C + +C L N +G F
Sbjct: 199 DCPGHRCLNGGTCVDGVNTYNCQC--PPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLG 256
Query: 279 CAECVCHDG--NMQCTRVDPELACP----RLPC-DPPQQF--SVP-GECCKFCPGVDYCN 328
CVC +G C++ + A C D F + P G+ C D C
Sbjct: 257 GHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDAC- 315
Query: 329 MGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + C E+A C +N + C C GF G G QDVDEC + + C RCVN
Sbjct: 316 VSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECS----IGANPCEHLGRCVN 370
Query: 387 VVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
G ++CQC GYT C +V+EC C A C + G +TC C G+ G
Sbjct: 371 TQGSFLCQCGRGYTGP---RCETDVNECLSGP--CRNQATCLDRIGQFTCICMAGFTGT- 424
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
Y + +DEC S C + C + GF C C
Sbjct: 425 YCEVDIDECQ--SSPCVNGGVCKDRVNGFSCTC 455
Score = 85.8 bits (203), Expect = 4e-16
Identities = 54/157 (34%), Positives = 76/157 (48%), Gaps = 20/157 (12%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNT 382
V+ C G C ATC++ ++TC C GF G C+ D+DECQ + ++G C
Sbjct: 392 VNECLSG-PCRNQATCLDRIGQFTCICMAGFTGT--YCEVDIDECQSSPCVNGGVCKDR- 447
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
V G+ C C G++ C ++VDEC C A C + P Y CRC +G+
Sbjct: 448 -----VNGFSCTCPSGFSGS---TCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGF 497
Query: 442 EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
EG +VD+C+ CHH RCV+ F C C
Sbjct: 498 EGT-LCDRNVDDCS--PDPCHH-GRCVDGIASFSCAC 530
Score = 84.6 bits (200), Expect = 1e-15
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 22/214 (10%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P C C G D C C P Q G C+ VD C +G C
Sbjct: 80 PDPCLSSPCAHGARCSVGPDGRFLCS---CPPGYQ----GRSCR--SDVDECRVGEPCRH 130
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQC 395
TC+N + C+C G+ G L C + +G C + Y C C
Sbjct: 131 GGTCLNTPGSFRCQCPAGYTGP-LCENPAVPCAPSPCRNGGTCRQSGDLT-----YDCAC 184
Query: 396 LGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
L G+ + NC V VD+C G H C C + +Y C+C + G + VDEC
Sbjct: 185 LPGFEGQ---NCEVNVDDCPG--HRCLNGGTCVDGVNTYNCQCPPEWTGQ-FCTEDVDEC 238
Query: 455 TEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
+ CH+ C N GG C C SCS
Sbjct: 239 QLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 272
Score = 81.4 bits (192), Expect = 9e-15
Identities = 79/277 (28%), Positives = 114/277 (41%), Gaps = 37/277 (13%)
Query: 228 HGEITC--RPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEH-GERFAPKECAECVC 284
H + C PV RA C P G C + +C + N EH G + C C
Sbjct: 321 HEDAICDTNPVN-GRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 379
Query: 285 HDG--NMQC-TRVDPELACP---RLPC-DPPQQFS---VPGECCKFCP-GVDYCNMGHSC 333
G +C T V+ L+ P + C D QF+ + G +C +D C C
Sbjct: 380 GRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSS-PC 438
Query: 334 DENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C + ++C C GF G TCQ DVDEC C + +CV+ GY
Sbjct: 439 VNGGVCKDRVNGFSCTCPSGFSGS--TCQLDVDECASTP------CRNGAKCVDQPDGYE 490
Query: 393 CQCLGGY--TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
C+C G+ T D+ VD+C + CH C + S++C C GY G
Sbjct: 491 CRCAEGFEGTLCDR----NVDDCSPDP--CHHGR-CVDGIASFSCACAPGYTGTRCESQ- 542
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
VDEC S C H +C+++ + C C + ++C
Sbjct: 543 VDECR--SQPCRHGGKCLDLVDKYLCRCPSGTTGVNC 577
Score = 76.2 bits (179), Expect = 3e-13
Identities = 79/270 (29%), Positives = 106/270 (39%), Gaps = 34/270 (12%)
Query: 250 PGECCPTCLRQCLLWGNL-YEHGERFAPKECAECVCHDG--NMQCTRVDPELACPRLPCD 306
PG P CL + HG + CVC G +C++ AC PC
Sbjct: 645 PGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCR 704
Query: 307 PPQQFSVPGEC--CKFCPGVD--YCNM-----GHSCDENATCMNLNTKY-TCKCNQGFQG 356
S G C PGV C + + C+ C + + C C QG+QG
Sbjct: 705 AGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQG 764
Query: 357 DGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEG 415
QDVDEC AG C + C N+ G + C C GGYT +C ++++C+
Sbjct: 765 PRCQ-QDVDEC--AGPAP---CGPHGICTNLAGSFSCTCHGGYTGP---SCDQDINDCDP 815
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTE---GSHTC-HHSAR----C 467
N C C + GS++C C G+ G VDEC G TC H A C
Sbjct: 816 NP--CLNGGSCQDGVGSFSCSCLPGFAGPR-CARDVDECLSNPCGPGTCTDHVASFTCTC 872
Query: 468 VNIDGGFRCECFTENCELSCSWQGRVVSEG 497
GGF CE +C S + G +G
Sbjct: 873 PPGYGGFHCEQDLPDCSPSSCFNGGTCVDG 902
Score = 74.9 bits (176), Expect = 8e-13
Identities = 66/218 (30%), Positives = 90/218 (41%), Gaps = 31/218 (14%)
Query: 282 CVCHDGNM--QCTR-VDPELACPRLPCDPPQQFSVPGECCKFCPG---------VDYCNM 329
CVC +G C + VDP LA P + + + G C+ PG VD C
Sbjct: 1030 CVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGY-MGGYMCECLPGYNGDNCEDDVDEC-A 1087
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLH-GHHCHSNTRCVNV 387
C +C++L +Y C C G G + C+ + D+C L G C N CV++
Sbjct: 1088 SQPCQHGGSCIDLVARYLCSCPPGTLG--VLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1145
Query: 388 VGGYVCQCLGGYTRKDKFNC-VEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
VGG+ C C GYT C +++EC G H H + G + C C G+ G
Sbjct: 1146 VGGFRCTCPPGYT---GLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGP- 1201
Query: 446 YTCMHVDECTEGSHTCHHSARC---VNIDGG--FRCEC 478
C V E S C H +C GG F C C
Sbjct: 1202 -RCQTVLSPCE-SQPCQHGGQCRPSPGPGGGLTFTCHC 1237
Score = 73.7 bits (173), Expect = 2e-12
Identities = 86/296 (29%), Positives = 111/296 (37%), Gaps = 43/296 (14%)
Query: 223 RCSCVHGEITCRPVECDRA-ECKNPVLHPGECCPTCL--RQCLLWG----NLYEHGERF- 274
RCS C C C + + CP + RQC L N EHG R
Sbjct: 688 RCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCE 747
Query: 275 -APKECAECVCHDG--NMQCTRVDPELACPRLPCDPPQQFS-VPGECCKFCPGV---DYC 327
AP + C C G +C + E A P PC P + + G C G C
Sbjct: 748 SAPGQLPVCSCPQGWQGPRCQQDVDECAGPA-PCGPHGICTNLAGSFSCTCHGGYTGPSC 806
Query: 328 NMG-HSCDEN-----ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSN 381
+ + CD N +C + ++C C GF G +DVDEC + C
Sbjct: 807 DQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCA-RDVDECLS------NPCGPG 859
Query: 382 TRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
T C + V + C C GY F+C E D + + C C + S++C CR GY
Sbjct: 860 T-CTDHVASFTCTCPPGY---GGFHC-EQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 914
Query: 442 EGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCEC---FT-ENCELSCSWQGR 492
G C H D C S C H C GFRC C FT C+ W R
Sbjct: 915 --TGAHCQHEADPCL--SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSR 966
Score = 69.3 bits (162), Expect = 4e-11
Identities = 72/275 (26%), Positives = 98/275 (35%), Gaps = 38/275 (13%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTC---LRQCLLWGNLYEHGERFAP 276
DC C G CR +R +C V PG P C + +C E G
Sbjct: 583 DCASNPCTFG--VCRD-GINRYDC---VCQPGFTGPLCNVEINECAS-SPCGEGGSCVDG 635
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFC-PGV----------- 324
+ C+C G++ + P C PC + PG C PG
Sbjct: 636 ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLAR 695
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
D C C TC + + C C G QG C+ + C HG C S
Sbjct: 696 DACE-SQPCRAGGTCSSDGMGFHCTCPPGVQGR--QCELLSPCTPNPCEHGGRCESAPGQ 752
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
+ V C C G+ C + VDEC G C +CTN GS++C C GY G
Sbjct: 753 LPV-----CSCPQGWQGP---RCQQDVDECAGPAP-CGPHGICTNLAGSFSCTCHGGYTG 803
Query: 444 DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+++C + C + C + G F C C
Sbjct: 804 PSCD-QDINDC--DPNPCLNGGSCQDGVGSFSCSC 835
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 17/149 (11%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNL----NTKYTCKCNQGFQ 355
C +LP PG + C D C+ G C C + +++C+C +GF+
Sbjct: 15 CTQLPSREAACLCPPGWVGERCQLEDPCHSG-PCAGRGVCQSSVVAGTARFSCRCPRGFR 73
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECE 414
G C D C + HG C V G ++C C GY + +C +VDEC
Sbjct: 74 GP--DCSLPDPCLSSPCAHGARC-----SVGPDGRFLCSCPPGYQGR---SCRSDVDECR 123
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C NTPGS+ C+C GY G
Sbjct: 124 VG-EPCRHGGTCLNTPGSFRCQCPAGYTG 151
Score = 56.4 bits (130), Expect = 3e-07
Identities = 69/276 (25%), Positives = 101/276 (36%), Gaps = 44/276 (15%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPK-E 278
+C CV+G + C+ + C P G C + +C +G + + +
Sbjct: 432 ECQSSPCVNGGV-CKD-RVNGFSCTCPSGFSGSTCQLDVDECA--STPCRNGAKCVDQPD 487
Query: 279 CAECVCHDGNMQCTRVDPELA-CPRLPC------DPPQQFS---VPGECCKFCPG-VDYC 327
EC C +G + T D + C PC D FS PG C VD C
Sbjct: 488 GYECRCAEG-FEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDEC 546
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVN 386
C C++L KY C+C G G+ C+ ++D+C + C C +
Sbjct: 547 R-SQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDCA------SNPCTFGV-CRD 596
Query: 387 VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ Y C C G+T VE++EC + C C + + C C G
Sbjct: 597 GINRYDCVCQPGFT--GPLCNVEINECASSP--CGEGGSCVDGENGFRCLCPPG------ 646
Query: 447 TCMHVDECTEGSHTCHHS----ARCVNIDGGFRCEC 478
C SH C H C + GGFRC C
Sbjct: 647 --SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVC 680
Score = 52.4 bits (120), Expect = 5e-06
Identities = 77/299 (25%), Positives = 101/299 (33%), Gaps = 43/299 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCL 258
DC + NG DG CSC+ G R D EC + PG C
Sbjct: 812 DCDPNPCLNGGSCQDGV----GSFSCSCLPGFAGPRCAR-DVDECLSNPCGPGTCTDHVA 866
Query: 259 RQCLLWGNLYE--HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGE 316
Y H E+ P +C+ C +G C +C C P G
Sbjct: 867 SFTCTCPPGYGGFHCEQDLP-DCSPSSCFNGGT-CVDGVNSFSCL---CRP----GYTGA 917
Query: 317 CCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHG 375
C+ D C + C C + + C C + F G CQ VD C
Sbjct: 918 HCQH--EADPC-LSRPCLHGGVCSAAHPGFRCTCLESFTGP--QCQTLVDWCSR------ 966
Query: 376 HHCHSNTRCVNVVGGYVCQCLGGYTRK----DKFNCVEVDECEGNT--HGCHADAVCTNT 429
C + RCV G Y C C G++ + C E G C A C +
Sbjct: 967 QPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDE 1024
Query: 430 PGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT----ENCE 484
S+ C C +G G + VD C + C H C GG+ CEC +NCE
Sbjct: 1025 DSSHYCVCPEGRTG-SHCEQEVDPCL--AQPCQHGGTCRGYMGGYMCECLPGYNGDNCE 1080
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 98.7 bits (235), Expect = 6e-20
Identities = 57/164 (34%), Positives = 76/164 (46%), Gaps = 17/164 (10%)
Query: 319 KFCP-GVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGH 376
+FC VD C + ++C TC N ++C C G+ G+ + Q++D+C A HG
Sbjct: 272 QFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS-QNIDDCATAVCFHGA 330
Query: 377 HCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP--GSYT 434
CH V + C C G K C D C N CH DA+C P G
Sbjct: 331 TCHDR------VASFYCACPMG---KTGLLCHLDDACVSNP--CHEDAICDTNPVNGRAI 379
Query: 435 CRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C C G+ G G VDEC+ G++ C H RCVN G F C+C
Sbjct: 380 CTCPPGFTG-GACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 422
Score = 87.0 bits (206), Expect = 2e-16
Identities = 52/165 (31%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 333 CDENATCMNL-NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGG 390
C TC + Y C C GF+G C+ +VD+C GH C + CV+ V
Sbjct: 209 CRNGGTCRQSGDLTYDCACLPGFEGQN--CEVNVDDCP------GHRCLNGGTCVDGVNT 260
Query: 391 YVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
Y CQC +T +F +VDEC+ + CH C NT G ++C C +G+ G+ + +
Sbjct: 261 YNCQCPPEWT--GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS-QN 317
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
+D+C C H A C + F C C L C VS
Sbjct: 318 IDDCATA--VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS 360
Score = 87.0 bits (206), Expect = 2e-16
Identities = 81/273 (29%), Positives = 112/273 (41%), Gaps = 30/273 (10%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGER-FAPKE 278
DC C++G V +C P G+ C + +C L N +G F
Sbjct: 242 DCPGHRCLNGGTCVDGVNTYNCQC--PPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLG 299
Query: 279 CAECVCHDG--NMQCTRVDPELACP----RLPC-DPPQQF--SVP-GECCKFCPGVDYCN 328
CVC +G C++ + A C D F + P G+ C D C
Sbjct: 300 GHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDAC- 358
Query: 329 MGHSCDENATCMN--LNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + C E+A C +N + C C GF G G QDVDEC + + C RCVN
Sbjct: 359 VSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECS----IGANPCEHLGRCVN 413
Query: 387 VVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
G ++CQC GYT C +V+EC C A C + G +TC C G+ G
Sbjct: 414 TQGSFLCQCGRGYTGP---RCETDVNECLSGP--CRNQATCLDRIGQFTCICMAGFTGT- 467
Query: 446 YTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
Y + +DEC S C + C + GF C C
Sbjct: 468 YCEVDIDECQ--SSPCVNGGVCKDRVNGFSCTC 498
Score = 85.8 bits (203), Expect = 4e-16
Identities = 54/157 (34%), Positives = 76/157 (48%), Gaps = 20/157 (12%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNT 382
V+ C G C ATC++ ++TC C GF G C+ D+DECQ + ++G C
Sbjct: 435 VNECLSG-PCRNQATCLDRIGQFTCICMAGFTGT--YCEVDIDECQSSPCVNGGVCKDR- 490
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
V G+ C C G++ C ++VDEC C A C + P Y CRC +G+
Sbjct: 491 -----VNGFSCTCPSGFSGS---TCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGF 540
Query: 442 EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
EG +VD+C+ CHH RCV+ F C C
Sbjct: 541 EGT-LCDRNVDDCS--PDPCHH-GRCVDGIASFSCAC 573
Score = 84.6 bits (200), Expect = 1e-15
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 22/214 (10%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P C C G D C C P Q G C+ VD C +G C
Sbjct: 123 PDPCLSSPCAHGARCSVGPDGRFLCS---CPPGYQ----GRSCR--SDVDECRVGEPCRH 173
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQC 395
TC+N + C+C G+ G L C + +G C + Y C C
Sbjct: 174 GGTCLNTPGSFRCQCPAGYTGP-LCENPAVPCAPSPCRNGGTCRQSGDLT-----YDCAC 227
Query: 396 LGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDEC 454
L G+ + NC V VD+C G H C C + +Y C+C + G + VDEC
Sbjct: 228 LPGFEGQ---NCEVNVDDCPG--HRCLNGGTCVDGVNTYNCQCPPEWTGQ-FCTEDVDEC 281
Query: 455 TEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
+ CH+ C N GG C C SCS
Sbjct: 282 QLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 315
Score = 81.4 bits (192), Expect = 9e-15
Identities = 79/277 (28%), Positives = 114/277 (41%), Gaps = 37/277 (13%)
Query: 228 HGEITC--RPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEH-GERFAPKECAECVC 284
H + C PV RA C P G C + +C + N EH G + C C
Sbjct: 364 HEDAICDTNPVN-GRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQC 422
Query: 285 HDG--NMQC-TRVDPELACP---RLPC-DPPQQFS---VPGECCKFCP-GVDYCNMGHSC 333
G +C T V+ L+ P + C D QF+ + G +C +D C C
Sbjct: 423 GRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSS-PC 481
Query: 334 DENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C + ++C C GF G TCQ DVDEC C + +CV+ GY
Sbjct: 482 VNGGVCKDRVNGFSCTCPSGFSGS--TCQLDVDECASTP------CRNGAKCVDQPDGYE 533
Query: 393 CQCLGGY--TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
C+C G+ T D+ VD+C + CH C + S++C C GY G
Sbjct: 534 CRCAEGFEGTLCDR----NVDDCSPDP--CHHGR-CVDGIASFSCACAPGYTGTRCESQ- 585
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
VDEC S C H +C+++ + C C + ++C
Sbjct: 586 VDECR--SQPCRHGGKCLDLVDKYLCRCPSGTTGVNC 620
Score = 74.9 bits (176), Expect = 8e-13
Identities = 66/218 (30%), Positives = 90/218 (41%), Gaps = 31/218 (14%)
Query: 282 CVCHDGNM--QCTR-VDPELACPRLPCDPPQQFSVPGECCKFCPG---------VDYCNM 329
CVC +G C + VDP LA P + + + G C+ PG VD C
Sbjct: 1021 CVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGY-MGGYMCECLPGYNGDNCEDDVDEC-A 1078
Query: 330 GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLH-GHHCHSNTRCVNV 387
C +C++L +Y C C G G + C+ + D+C L G C N CV++
Sbjct: 1079 SQPCQHGGSCIDLVARYLCSCPPGTLG--VLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1136
Query: 388 VGGYVCQCLGGYTRKDKFNC-VEVDEC-EGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
VGG+ C C GYT C +++EC G H H + G + C C G+ G
Sbjct: 1137 VGGFRCTCPPGYT---GLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGP- 1192
Query: 446 YTCMHVDECTEGSHTCHHSARC---VNIDGG--FRCEC 478
C V E S C H +C GG F C C
Sbjct: 1193 -RCQTVLSPCE-SQPCQHGGQCRPSPGPGGGLTFTCHC 1228
Score = 73.3 bits (172), Expect = 2e-12
Identities = 69/223 (30%), Positives = 87/223 (39%), Gaps = 38/223 (17%)
Query: 282 CVCHDG--NMQCTRVDPELACPRLPCDPPQQF-SVPGEC--CKFCPG--VDYCNMGHSCD 334
C C G QC + P C PC+ + S PG+ C CP D C G SC
Sbjct: 761 CTCPPGVQGRQCELLSP---CTPNPCEHGGRCESAPGQLPVCS-CPQGWQDPCLNGGSCQ 816
Query: 335 ENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
+ ++C C GF G +DVDEC + C T C + V + C
Sbjct: 817 DGVG------SFSCSCLPGFAGPRCA-RDVDECLS------NPCGPGT-CTDHVASFTCT 862
Query: 395 CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDE 453
C GY F+C E D + + C C + S++C CR GY G C H D
Sbjct: 863 CPPGY---GGFHC-EQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY--TGAHCQHEADP 916
Query: 454 CTEGSHTCHHSARCVNIDGGFRCEC---FT-ENCELSCSWQGR 492
C S C H C GFRC C FT C+ W R
Sbjct: 917 CL--SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSR 957
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 17/149 (11%)
Query: 300 CPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNL----NTKYTCKCNQGFQ 355
C +LP PG + C D C+ G C C + +++C+C +GF+
Sbjct: 58 CTQLPSREAACLCPPGWVGERCQLEDPCHSG-PCAGRGVCQSSVVAGTARFSCRCPRGFR 116
Query: 356 GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECE 414
G C D C + HG C V G ++C C GY + +C +VDEC
Sbjct: 117 GP--DCSLPDPCLSSPCAHGARC-----SVGPDGRFLCSCPPGYQGR---SCRSDVDECR 166
Query: 415 GNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C NTPGS+ C+C GY G
Sbjct: 167 VG-EPCRHGGTCLNTPGSFRCQCPAGYTG 194
Score = 56.4 bits (130), Expect = 3e-07
Identities = 69/276 (25%), Positives = 101/276 (36%), Gaps = 44/276 (15%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPK-E 278
+C CV+G + C+ + C P G C + +C +G + + +
Sbjct: 475 ECQSSPCVNGGV-CKD-RVNGFSCTCPSGFSGSTCQLDVDECA--STPCRNGAKCVDQPD 530
Query: 279 CAECVCHDGNMQCTRVDPELA-CPRLPC------DPPQQFS---VPGECCKFCPG-VDYC 327
EC C +G + T D + C PC D FS PG C VD C
Sbjct: 531 GYECRCAEG-FEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDEC 589
Query: 328 NMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVN 386
C C++L KY C+C G G+ C+ ++D+C + C C +
Sbjct: 590 R-SQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDCA------SNPCTFGV-CRD 639
Query: 387 VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ Y C C G+T VE++EC + C C + + C C G
Sbjct: 640 GINRYDCVCQPGFT--GPLCNVEINECASSP--CGEGGSCVDGENGFRCLCPPG------ 689
Query: 447 TCMHVDECTEGSHTCHHS----ARCVNIDGGFRCEC 478
C SH C H C + GGFRC C
Sbjct: 690 --SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVC 723
Score = 52.4 bits (120), Expect = 5e-06
Identities = 80/313 (25%), Positives = 107/313 (34%), Gaps = 48/313 (15%)
Query: 189 EARISRLEQCDC----QKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECK 244
E+ +L C C Q C + G+ DG CSC+ G R D EC
Sbjct: 790 ESAPGQLPVCSCPQGWQDPCLNGGSCQ-DGV----GSFSCSCLPGFAGPRCAR-DVDECL 843
Query: 245 NPVLHPGECCPTCLRQCLLWGNLYE--HGERFAPKECAECVCHDGNMQCTRVDPELACPR 302
+ PG C Y H E+ P +C+ C +G C +C
Sbjct: 844 SNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLP-DCSPSSCFNGGT-CVDGVNSFSCL- 900
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
C P G C+ D C + C C + + C C + F G CQ
Sbjct: 901 --CRP----GYTGAHCQH--EADPC-LSRPCLHGGVCSAAHPGFRCTCLESFTGP--QCQ 949
Query: 363 D-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK----DKFNCVEVDECEGNT 417
VD C C + RCV G Y C C G++ + C E G
Sbjct: 950 TLVDWCSR------QPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVR 1001
Query: 418 --HGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
C A C + S+ C C +G G + VD C + C H C GG+
Sbjct: 1002 LEQLCQAGGQCVDEDSSHYCVCPEGRTG-SHCEQEVDPCL--AQPCQHGGTCRGYMGGYM 1058
Query: 476 CECFT----ENCE 484
CEC +NCE
Sbjct: 1059 CECLPGYNGDNCE 1071
Score = 48.0 bits (109), Expect = 1e-04
Identities = 78/301 (25%), Positives = 103/301 (34%), Gaps = 56/301 (18%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTC---LRQCLLWGNLYEHGERFAP 276
DC C G CR +R +C V PG P C + +C E G
Sbjct: 626 DCASNPCTFG--VCRD-GINRYDC---VCQPGFTGPLCNVEINECAS-SPCGEGGSCVDG 678
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFC-PGV----------- 324
+ C+C G++ + P C PC + PG C PG
Sbjct: 679 ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLAR 738
Query: 325 DYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
D C C TC + + C C G QG C+ + C HG C S
Sbjct: 739 DACE-SQPCRAGGTCSSDGMGFHCTCPPGVQGR--QCELLSPCTPNPCEHGGRCESAPGQ 795
Query: 385 VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+ V C C G+ +D C+ C+ D V GS++C C G+ G
Sbjct: 796 LPV-----CSCPQGW--QDP--CLNGGSCQ--------DGV-----GSFSCSCLPGFAGP 833
Query: 445 GYTCMHVDECTE---GSHTC-HHSAR----CVNIDGGFRCECFTENCELSCSWQGRVVSE 496
VDEC G TC H A C GGF CE +C S + G +
Sbjct: 834 R-CARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD 892
Query: 497 G 497
G
Sbjct: 893 G 893
Score = 46.8 bits (106), Expect = 2e-04
Identities = 70/297 (23%), Positives = 95/297 (31%), Gaps = 39/297 (13%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRA--ECK 244
G +L+ +C + NG D Q D C C G CDR +C
Sbjct: 501 GFSGSTCQLDVDECASTPCRNGAKCVD----QPDGYECRCAEG---FEGTLCDRNVDDCS 553
Query: 245 NPVLHPGECCPTCLRQCLLWGNLYEHGERFAPK--ECAECVCHDGNMQCTRVDPELA-CP 301
H G C Y G R + EC C G VD L CP
Sbjct: 554 PDPCHHGRCVDGIASFSCACAPGYT-GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCP 612
Query: 302 RLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTC 361
G C+ +D C + C C + +Y C C GF G L
Sbjct: 613 S---------GTTGVNCEV--NIDDC-ASNPCTFGV-CRDGINRYDCVCQPGFTGP-LCN 658
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH 421
+++EC + C CV+ G+ C C G E +HG
Sbjct: 659 VEINECASSP------CGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-- 710
Query: 422 ADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C + PG + C C G+ G + + E S C C + GF C C
Sbjct: 711 ---ICYDAPGGFRCVCEPGWSGPRCSQSLARDACE-SQPCRAGGTCSSDGMGFHCTC 763
>AK122706-1|BAC85504.1| 814|Homo sapiens ISOFORM. protein.
Length = 814
Score = 98.3 bits (234), Expect = 7e-20
Identities = 66/237 (27%), Positives = 104/237 (43%), Gaps = 20/237 (8%)
Query: 200 CQKSCYSNGTVHADGATW---QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPT 256
C+ C G ++ +G T+ + C +C+C+ + C ++C + C PVL PG CCPT
Sbjct: 188 CKPGCDYEGQLYEEGVTFLSSSKPCLQCTCLRSRVRCMALKCPPSPCPEPVLRPGHCCPT 247
Query: 257 CLRQCLLWGNLYEHGERF-APKE-CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP 314
C + C G+ +EHG+ + P + C C C +G++QC + + CP P P +P
Sbjct: 248 C-QGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCP-YPARP-----LP 300
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKC-NQGFQGDGLTCQDVDECQEAGGL 373
G CC C G H E + + C+C N Q + L C V C+ G +
Sbjct: 301 GTCCPVCDGCFLNGREHRSGEPVGSGDPCSH--CRCANGSVQCEPLPCPPV-PCRHPGKI 357
Query: 374 HGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP 430
G C C G+ Q + +++ CV C+ C + C TP
Sbjct: 358 PGQCCPVCDGC--EYQGHQYQSQETFRLQERGLCVRC-SCQAGEVSCE-EQECPVTP 410
Score = 92.3 bits (219), Expect = 5e-18
Identities = 47/125 (37%), Positives = 60/125 (48%), Gaps = 12/125 (9%)
Query: 203 SCYSNGTVHADGATWQRD---CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLR 259
+C +G A+G W+ D C C C G C V C A C++P PG CCP+C
Sbjct: 423 ACELDGEEFAEGVQWEPDGRPCTACVCQDGVPECGAVLCPPAPCQHPTQPPGACCPSC-D 481
Query: 260 QCLLWGNLYEHGERF--APKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGEC 317
C +Y +G+ F A C C C DG + C+ VD CP C PQ S PG+C
Sbjct: 482 SCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVD----CPPTTCARPQ--SGPGQC 535
Query: 318 CKFCP 322
C CP
Sbjct: 536 CPRCP 540
Score = 89.8 bits (213), Expect = 3e-17
Identities = 46/125 (36%), Positives = 56/125 (44%), Gaps = 13/125 (10%)
Query: 202 KSCYSNGTVHADGATWQRD-CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQ 260
+ C NG + +G T+ D C C C+ G ITC C R C PG CCP C
Sbjct: 136 RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRGPCP----EPGACCPHCKPG 191
Query: 261 CLLWGNLYEHGERF--APKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECC 318
C G LYE G F + K C +C C ++C L CP PC P+ PG CC
Sbjct: 192 CDYEGQLYEEGVTFLSSSKPCLQCTCLRSRVRCM----ALKCPPSPC--PEPVLRPGHCC 245
Query: 319 KFCPG 323
C G
Sbjct: 246 PTCQG 250
Score = 85.8 bits (203), Expect = 4e-16
Identities = 45/126 (35%), Positives = 62/126 (49%), Gaps = 14/126 (11%)
Query: 198 CDCQKSCYSNGTVHADGATW---QRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECC 254
C SC + V+A+G + C+ C C G +TC V+C C P PG+CC
Sbjct: 477 CPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCC 536
Query: 255 PTCLRQCLLWGNLYEHGERFA-PKE-CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
P C C+L ++ GE F+ P++ C EC C +G+ C P CPR PC P
Sbjct: 537 PRC-PDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHC---QPR-PCPRAPCAHP---- 587
Query: 313 VPGECC 318
+PG CC
Sbjct: 588 LPGTCC 593
Score = 82.2 bits (194), Expect = 5e-15
Identities = 48/130 (36%), Positives = 57/130 (43%), Gaps = 13/130 (10%)
Query: 198 CDCQKSCYSNGTVHADGATWQ--RD-CNRCSCVHGEITCRPVECDRAECKNPVLHPGECC 254
C C V DG ++ RD C C C G C+P C RA C +P+ PG CC
Sbjct: 536 CPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL--PGTCC 593
Query: 255 PTCLRQCLLWGNLYEHGERFA-PKE-CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
P C G Y G F P + C C C GN+QC C LPC P+
Sbjct: 594 PNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCL----ARRCVPLPC--PEPVL 647
Query: 313 VPGECCKFCP 322
+PGECC CP
Sbjct: 648 LPGECCPQCP 657
Score = 79.0 bits (186), Expect = 5e-14
Identities = 49/139 (35%), Positives = 59/139 (42%), Gaps = 20/139 (14%)
Query: 199 DCQKSCYSNGTVHADGATWQRD---CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCP 255
DC C G + GA + C C C+ G + C C C PVL PGECCP
Sbjct: 596 DCS-GCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCP 654
Query: 256 TCLRQ-----CLLWGNLY-EHGERFAPK--ECAECVCHDGNMQCTRVDPELACPRLPCDP 307
C C G + H E F+P C C+C DG++ C R L CP PC
Sbjct: 655 QCPAAPAPAGCPRPGAAHARHQEYFSPPGVPCRRCLCLDGSVSCQR----LPCPPAPCAH 710
Query: 308 PQQFSVPGECCKFCPGVDY 326
P+Q G CC C G Y
Sbjct: 711 PRQ----GPCCPSCDGCLY 725
Score = 74.5 bits (175), Expect = 1e-12
Identities = 48/147 (32%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
Query: 221 CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAP--KE 278
C RCSC GE++C EC C P + CP C L G + G ++ P +
Sbjct: 389 CVRCSCQAGEVSCEEQECPVTPCALPA-SGRQLCPA----CELDGEEFAEGVQWEPDGRP 443
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
C CVC DG +C V CP PC P Q PG CC C Y + ++ +N T
Sbjct: 444 CTACVCQDGVPECGAV----LCPPAPCQHPTQ--PPGACCPSCDSCTYHSQVYANGQNFT 497
Query: 339 CMNLNTKYTCKCNQGFQGDGLTCQDVD 365
+ + + C C G +TC VD
Sbjct: 498 DAD-SPCHACHCQDG----TVTCSLVD 519
Score = 41.5 bits (93), Expect = 0.009
Identities = 21/45 (46%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 555 CCPHCDARYHCRHQEMHHVTFRSGERWLYQCQICECLLGEVDCWE 599
CCP CD + HQ TFR ER L C C C GEV C E
Sbjct: 361 CCPVCDGCEYQGHQYQSQETFRLQERGL--CVRCSCQAGEVSCEE 403
Score = 40.3 bits (90), Expect = 0.021
Identities = 20/63 (31%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 198 CDCQKSCYSNGTVHADGATWQRD---CNRCSCVHGEITCRPVECDRAECKNPVLHPGECC 254
C C G A G + C+ C C G ++C P C A C P G+CC
Sbjct: 717 CPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPA--RGDCC 774
Query: 255 PTC 257
P C
Sbjct: 775 PDC 777
Score = 35.9 bits (79), Expect = 0.45
Identities = 16/40 (40%), Positives = 18/40 (45%), Gaps = 1/40 (2%)
Query: 252 ECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQC 291
EC P QC G + G R+ P C CVC DG C
Sbjct: 88 ECHPAS-PQCWGLGRAWPEGARWEPDACTACVCQDGAAHC 126
Score = 31.5 bits (68), Expect = 9.7
Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 10/49 (20%)
Query: 555 CCPHCDARYHCRHQEMHHVTFRSGERW---LYQCQICECLLGEVDCWEP 600
CCP CD C +Q F SGER+ C +C C G V C EP
Sbjct: 716 CCPSCDG---CLYQGKE---FASGERFPSPTAACHLCLCWEGSVSC-EP 757
>U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein.
Length = 652
Score = 96.3 bits (229), Expect = 3e-19
Identities = 61/156 (39%), Positives = 73/156 (46%), Gaps = 22/156 (14%)
Query: 333 CDENATCM--NLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
C ATC+ YTC+C QG+Q D L C DVDECQ++ C CVN
Sbjct: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP------CAQE--CVNTP 362
Query: 389 GGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EG 443
GG+ C+C GY + C +VDEC C CTNT GS+ C C +GY
Sbjct: 363 GGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGE 420
Query: 444 DGYTCMHVDECT-EGSHTCHHSARCVNIDGGFRCEC 478
DG C VDEC G C + C N G F C C
Sbjct: 421 DGTQCQDVDECVGPGGPLC--DSLCFNTQGSFHCGC 454
Score = 81.0 bits (191), Expect = 1e-14
Identities = 50/142 (35%), Positives = 65/142 (45%), Gaps = 22/142 (15%)
Query: 346 YTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG--YVCQCLGGYTR 401
+ C C GF+ D +TC + C + C CV G Y C+C GY
Sbjct: 283 FLCGCRPGFRLLDDLVTCASRNPCSSSP------CRGGATCVLGPHGKNYTCRCPQGYQL 336
Query: 402 -KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE----GDGYTCMHVDECTE 456
+ +CV+VDEC+ + C + C NTPG + C C GYE G+G C VDEC
Sbjct: 337 DSSQLDCVDVDECQDSP--CAQE--CVNTPGGFRCECWVGYEPGGPGEG-ACQDVDECAL 391
Query: 457 GSHTCHHSARCVNIDGGFRCEC 478
G C + C N DG F C C
Sbjct: 392 GRSPC--AQGCTNTDGSFHCSC 411
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/143 (33%), Positives = 63/143 (44%), Gaps = 18/143 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ----GDGLT 360
C PQ + + C VD C E C+N + C+C G++ G+G
Sbjct: 328 CRCPQGYQLDSSQLD-CVDVDECQDSPCAQE---CVNTPGGFRCECWVGYEPGGPGEG-A 382
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTH 418
CQDVDEC L C C N G + C C GY +D C +VDEC G
Sbjct: 383 CQDVDEC----ALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG-PG 435
Query: 419 GCHADAVCTNTPGSYTCRCRDGY 441
G D++C NT GS+ C C G+
Sbjct: 436 GPLCDSLCFNTQGSFHCGCLPGW 458
Score = 62.9 bits (146), Expect = 3e-09
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
Query: 389 GGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGDG 445
G ++C C G+ D C + C + C A C P +YTCRC GY+ D
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 446 --YTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C+ VDEC + C + CVN GGFRCEC+
Sbjct: 339 SQLDCVDVDECQDSP--C--AQECVNTPGGFRCECW 370
>BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein.
Length = 652
Score = 96.3 bits (229), Expect = 3e-19
Identities = 61/156 (39%), Positives = 73/156 (46%), Gaps = 22/156 (14%)
Query: 333 CDENATCM--NLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
C ATC+ YTC+C QG+Q D L C DVDECQ++ C CVN
Sbjct: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP------CAQE--CVNTP 362
Query: 389 GGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EG 443
GG+ C+C GY + C +VDEC C CTNT GS+ C C +GY
Sbjct: 363 GGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGE 420
Query: 444 DGYTCMHVDECT-EGSHTCHHSARCVNIDGGFRCEC 478
DG C VDEC G C + C N G F C C
Sbjct: 421 DGTQCQDVDECVGPGGPLC--DSLCFNTQGSFHCGC 454
Score = 81.0 bits (191), Expect = 1e-14
Identities = 50/142 (35%), Positives = 65/142 (45%), Gaps = 22/142 (15%)
Query: 346 YTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG--YVCQCLGGYTR 401
+ C C GF+ D +TC + C + C CV G Y C+C GY
Sbjct: 283 FLCGCRPGFRLLDDLVTCASRNPCSSSP------CRGGATCVLGPHGKNYTCRCPQGYQL 336
Query: 402 -KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE----GDGYTCMHVDECTE 456
+ +CV+VDEC+ + C + C NTPG + C C GYE G+G C VDEC
Sbjct: 337 DSSQLDCVDVDECQDSP--CAQE--CVNTPGGFRCECWVGYEPGGPGEG-ACQDVDECAL 391
Query: 457 GSHTCHHSARCVNIDGGFRCEC 478
G C + C N DG F C C
Sbjct: 392 GRSPC--AQGCTNTDGSFHCSC 411
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/143 (33%), Positives = 63/143 (44%), Gaps = 18/143 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ----GDGLT 360
C PQ + + C VD C E C+N + C+C G++ G+G
Sbjct: 328 CRCPQGYQLDSSQLD-CVDVDECQDSPCAQE---CVNTPGGFRCECWVGYEPGGPGEG-A 382
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTH 418
CQDVDEC L C C N G + C C GY +D C +VDEC G
Sbjct: 383 CQDVDEC----ALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG-PG 435
Query: 419 GCHADAVCTNTPGSYTCRCRDGY 441
G D++C NT GS+ C C G+
Sbjct: 436 GPLCDSLCFNTQGSFHCGCLPGW 458
Score = 62.9 bits (146), Expect = 3e-09
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
Query: 389 GGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGDG 445
G ++C C G+ D C + C + C A C P +YTCRC GY+ D
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 446 --YTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C+ VDEC + C + CVN GGFRCEC+
Sbjct: 339 SQLDCVDVDECQDSP--C--AQECVNTPGGFRCECW 370
>AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1, q
subcomponent, receptor 1 protein.
Length = 652
Score = 96.3 bits (229), Expect = 3e-19
Identities = 61/156 (39%), Positives = 73/156 (46%), Gaps = 22/156 (14%)
Query: 333 CDENATCM--NLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
C ATC+ YTC+C QG+Q D L C DVDECQ++ C CVN
Sbjct: 311 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP------CAQE--CVNTP 362
Query: 389 GGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EG 443
GG+ C+C GY + C +VDEC C CTNT GS+ C C +GY
Sbjct: 363 GGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGE 420
Query: 444 DGYTCMHVDECT-EGSHTCHHSARCVNIDGGFRCEC 478
DG C VDEC G C + C N G F C C
Sbjct: 421 DGTQCQDVDECVGPGGPLC--DSLCFNTQGSFHCGC 454
Score = 81.0 bits (191), Expect = 1e-14
Identities = 50/142 (35%), Positives = 65/142 (45%), Gaps = 22/142 (15%)
Query: 346 YTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG--YVCQCLGGYTR 401
+ C C GF+ D +TC + C + C CV G Y C+C GY
Sbjct: 283 FLCGCRPGFRLLDDLVTCASRNPCSSSP------CRGGATCVLGPHGKNYTCRCPQGYQL 336
Query: 402 -KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE----GDGYTCMHVDECTE 456
+ +CV+VDEC+ + C + C NTPG + C C GYE G+G C VDEC
Sbjct: 337 DSSQLDCVDVDECQDSP--CAQE--CVNTPGGFRCECWVGYEPGGPGEG-ACQDVDECAL 391
Query: 457 GSHTCHHSARCVNIDGGFRCEC 478
G C + C N DG F C C
Sbjct: 392 GRSPC--AQGCTNTDGSFHCSC 411
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/143 (33%), Positives = 63/143 (44%), Gaps = 18/143 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ----GDGLT 360
C PQ + + C VD C E C+N + C+C G++ G+G
Sbjct: 328 CRCPQGYQLDSSQLD-CVDVDECQDSPCAQE---CVNTPGGFRCECWVGYEPGGPGEG-A 382
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTH 418
CQDVDEC L C C N G + C C GY +D C +VDEC G
Sbjct: 383 CQDVDEC----ALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG-PG 435
Query: 419 GCHADAVCTNTPGSYTCRCRDGY 441
G D++C NT GS+ C C G+
Sbjct: 436 GPLCDSLCFNTQGSFHCGCLPGW 458
Score = 62.9 bits (146), Expect = 3e-09
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
Query: 389 GGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGDG 445
G ++C C G+ D C + C + C A C P +YTCRC GY+ D
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS 338
Query: 446 --YTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C+ VDEC + C + CVN GGFRCEC+
Sbjct: 339 SQLDCVDVDECQDSP--C--AQECVNTPGGFRCECW 370
>AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1, q
subcomponent, receptor 1 variant protein.
Length = 671
Score = 96.3 bits (229), Expect = 3e-19
Identities = 61/156 (39%), Positives = 73/156 (46%), Gaps = 22/156 (14%)
Query: 333 CDENATCM--NLNTKYTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
C ATC+ YTC+C QG+Q D L C DVDECQ++ C CVN
Sbjct: 330 CRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP------CAQE--CVNTP 381
Query: 389 GGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EG 443
GG+ C+C GY + C +VDEC C CTNT GS+ C C +GY
Sbjct: 382 GGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGE 439
Query: 444 DGYTCMHVDECT-EGSHTCHHSARCVNIDGGFRCEC 478
DG C VDEC G C + C N G F C C
Sbjct: 440 DGTQCQDVDECVGPGGPLC--DSLCFNTQGSFHCGC 473
Score = 81.0 bits (191), Expect = 1e-14
Identities = 50/142 (35%), Positives = 65/142 (45%), Gaps = 22/142 (15%)
Query: 346 YTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGG--YVCQCLGGYTR 401
+ C C GF+ D +TC + C + C CV G Y C+C GY
Sbjct: 302 FLCGCRPGFRLLDDLVTCASRNPCSSSP------CRGGATCVLGPHGKNYTCRCPQGYQL 355
Query: 402 -KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE----GDGYTCMHVDECTE 456
+ +CV+VDEC+ + C + C NTPG + C C GYE G+G C VDEC
Sbjct: 356 DSSQLDCVDVDECQDSP--CAQE--CVNTPGGFRCECWVGYEPGGPGEG-ACQDVDECAL 410
Query: 457 GSHTCHHSARCVNIDGGFRCEC 478
G C + C N DG F C C
Sbjct: 411 GRSPC--AQGCTNTDGSFHCSC 430
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/143 (33%), Positives = 63/143 (44%), Gaps = 18/143 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ----GDGLT 360
C PQ + + C VD C E C+N + C+C G++ G+G
Sbjct: 347 CRCPQGYQLDSSQLD-CVDVDECQDSPCAQE---CVNTPGGFRCECWVGYEPGGPGEG-A 401
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTH 418
CQDVDEC L C C N G + C C GY +D C +VDEC G
Sbjct: 402 CQDVDEC----ALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG-PG 454
Query: 419 GCHADAVCTNTPGSYTCRCRDGY 441
G D++C NT GS+ C C G+
Sbjct: 455 GPLCDSLCFNTQGSFHCGCLPGW 477
Score = 62.9 bits (146), Expect = 3e-09
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
Query: 389 GGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGDG 445
G ++C C G+ D C + C + C A C P +YTCRC GY+ D
Sbjct: 300 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCVLGPHGKNYTCRCPQGYQLDS 357
Query: 446 --YTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C+ VDEC + C + CVN GGFRCEC+
Sbjct: 358 SQLDCVDVDECQDSP--C--AQECVNTPGGFRCECW 389
>AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein
protein.
Length = 652
Score = 95.9 bits (228), Expect = 4e-19
Identities = 62/156 (39%), Positives = 75/156 (48%), Gaps = 22/156 (14%)
Query: 333 CDENATC-MNLNTK-YTCKCNQGFQGDG--LTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
C ATC + + K YTC+C QG+Q D L C DVDECQ++ C CVN
Sbjct: 311 CRGGATCALGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSP------CAQE--CVNTP 362
Query: 389 GGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY---EG 443
GG+ C+C GY + C +VDEC C CTNT GS+ C C +GY
Sbjct: 363 GGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGE 420
Query: 444 DGYTCMHVDECT-EGSHTCHHSARCVNIDGGFRCEC 478
DG C VDEC G C + C N G F C C
Sbjct: 421 DGTQCQDVDECVGPGGPLC--DSLCFNTQGSFHCGC 454
Score = 81.0 bits (191), Expect = 1e-14
Identities = 49/140 (35%), Positives = 64/140 (45%), Gaps = 18/140 (12%)
Query: 346 YTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR-K 402
+ C C GF+ D +TC + C + G C N Y C+C GY
Sbjct: 283 FLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCALGPHGKN----YTCRCPQGYQLDS 338
Query: 403 DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE----GDGYTCMHVDECTEGS 458
+ +CV+VDEC+ + C + C NTPG + C C GYE G+G C VDEC G
Sbjct: 339 SQLDCVDVDECQDSP--CAQE--CVNTPGGFRCECWVGYEPGGPGEG-ACQDVDECALGR 393
Query: 459 HTCHHSARCVNIDGGFRCEC 478
C + C N DG F C C
Sbjct: 394 SPC--AQGCTNTDGSFHCSC 411
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/143 (33%), Positives = 63/143 (44%), Gaps = 18/143 (12%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ----GDGLT 360
C PQ + + C VD C E C+N + C+C G++ G+G
Sbjct: 328 CRCPQGYQLDSSQLD-CVDVDECQDSPCAQE---CVNTPGGFRCECWVGYEPGGPGEG-A 382
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTH 418
CQDVDEC L C C N G + C C GY +D C +VDEC G
Sbjct: 383 CQDVDEC----ALGRSPCAQG--CTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVG-PG 435
Query: 419 GCHADAVCTNTPGSYTCRCRDGY 441
G D++C NT GS+ C C G+
Sbjct: 436 GPLCDSLCFNTQGSFHCGCLPGW 458
Score = 62.9 bits (146), Expect = 3e-09
Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
Query: 389 GGYVCQCLGGYTRKDKF-NCVEVDECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGDG 445
G ++C C G+ D C + C + C A C P +YTCRC GY+ D
Sbjct: 281 GSFLCGCRPGFRLLDDLVTCASRNPCSSSP--CRGGATCALGPHGKNYTCRCPQGYQLDS 338
Query: 446 --YTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C+ VDEC + C + CVN GGFRCEC+
Sbjct: 339 SQLDCVDVDECQDSP--C--AQECVNTPGGFRCECW 370
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 95.9 bits (228), Expect = 4e-19
Identities = 86/297 (28%), Positives = 122/297 (41%), Gaps = 44/297 (14%)
Query: 199 DC-QKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKN-PVLHPGECCPT 256
DC + SC++ GT DG + C C G T + D EC + P LH G C
Sbjct: 498 DCTESSCFNGGTC-VDGI----NSFTCLCPPG-FTGSYCQHDVNECDSQPCLHGGTCQDG 551
Query: 257 C-LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQC--TRVDPELACPR----LPCDPPQ 309
C +C + C C +G +C T CP L CD P
Sbjct: 552 CGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG-KCWQTHTQYRCECPSGWTGLYCDVP- 609
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQ 368
SV E GVD + C C++ + C+C G+ G C+D VDEC
Sbjct: 610 --SVSCEVAAQRQGVDVARL---CQHGGLCVDAGNTHHCRCQAGYTGS--YCEDLVDECS 662
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCT 427
+ C + C + +GGY C+C+ GY NC E+DEC +H C C
Sbjct: 663 PSP------CQNGATCTDYLGGYSCKCVAGY---HGVNCSEEIDEC--LSHPCQNGGTCL 711
Query: 428 NTPGSYTCRCRDGYEGDGYTCMHVDEC------TEGSHTCHHSARCVNIDGGFRCEC 478
+ P +Y C C G +G + ++VD+C S C ++ CV+ GG+ C C
Sbjct: 712 DLPNTYKCSCPRGTQG-VHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTC 767
Score = 82.6 bits (195), Expect = 4e-15
Identities = 79/326 (24%), Positives = 123/326 (37%), Gaps = 43/326 (13%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGA-TWQRDCNR-CSCVHGEIT---CRPVECDRA 241
G + + + +C + NG DG T+ C + H E+ C P C
Sbjct: 31 GFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG 90
Query: 242 ECKNPVL---------HPGECCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDGNMQC 291
CK+ V + G C T + +C HG ++ A C C G
Sbjct: 91 SCKDGVATFTCLCRPGYTGHHCETNINECS--SQPCRHGGTCQDRDNAYLCFCLKGTTGP 148
Query: 292 TRVDPELACPRLPCDPPQQFS-VPGECCKFCPGV--DYCNM------GHSCDENATCMNL 342
C PCD + G C PG CN+ G+ C TC +
Sbjct: 149 NCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDG 208
Query: 343 NTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK 402
+TC+C +G+ D +V+EC +HG C + + GY C C G++
Sbjct: 209 INGFTCRCPEGYH-DPTCLSEVNECNSNPCVHG-------ACRDSLNGYKCDCDPGWSGT 260
Query: 403 DKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTC 461
NC + +ECE N C C + Y C CR+G+ G +++EC S+ C
Sbjct: 261 ---NCDINNNECESNP--CVNGGTCKDMTSGYVCTCREGFSGPNCQT-NINECA--SNPC 312
Query: 462 HHSARCVNIDGGFRCECFTENCELSC 487
+ C++ G++C C +C
Sbjct: 313 LNQGTCIDDVAGYKCNCLLPYTGATC 338
Score = 82.2 bits (194), Expect = 5e-15
Identities = 50/160 (31%), Positives = 77/160 (48%), Gaps = 23/160 (14%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C N C++ ++ C+C GF G CQ DVDEC C + +C++ Y
Sbjct: 11 CLHNGRCLDKINEFQCECPTGFTGH--LCQYDVDECAST------PCKNGAKCLDGPNTY 62
Query: 392 VCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMH 450
C C GYT +C V++DEC+ + CH + C + ++TC CR GY G + +
Sbjct: 63 TCVCTEGYTGT---HCEVDIDECDPDP--CHYGS-CKDGVATFTCLCRPGYTGH-HCETN 115
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECFT----ENCELS 486
++EC+ S C H C + D + C C NCE++
Sbjct: 116 INECS--SQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEIN 153
Score = 79.0 bits (186), Expect = 5e-14
Identities = 76/273 (27%), Positives = 107/273 (39%), Gaps = 35/273 (12%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPK-E 278
DC C G TC + D EC + G C + +C GN +G
Sbjct: 156 DCASSPCDSG--TCLD-KIDGYECACEPGYTGSMCNINIDECA--GNPCHNGGTCEDGIN 210
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCPGVDYCNM---GHSCD 334
C C +G T + C PC + S+ G C PG N + C+
Sbjct: 211 GFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECE 270
Query: 335 EN-----ATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVV 388
N TC ++ + Y C C +GF G CQ +++EC + C + C++ V
Sbjct: 271 SNPCVNGGTCKDMTSGYVCTCREGFSGP--NCQTNINECA------SNPCLNQGTCIDDV 322
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG--SYTCRCRDGYEGDGY 446
GY C CL YT C EV C C + S++C C G++G
Sbjct: 323 AGYKCNCLLPYTGA---TC-EVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQ-- 376
Query: 447 TC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
TC + ++EC C H A C N GG+RC C
Sbjct: 377 TCEVDINECV--LSPCRHGASCQNTHGGYRCHC 407
Score = 79.0 bits (186), Expect = 5e-14
Identities = 75/287 (26%), Positives = 117/287 (40%), Gaps = 33/287 (11%)
Query: 198 CDCQKS-CYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHPGECCP 255
CD + C SN V+ C+C G + + + EC NP L+ G C
Sbjct: 262 CDINNNECESNPCVNGGTCKDMTSGYVCTCREG-FSGPNCQTNINECASNPCLNQGTCID 320
Query: 256 TCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS 312
CLL AP CA C +G +C + + + C P +
Sbjct: 321 DVAGYKCNCLLPYTGATCEVVLAP--CAPSPCRNGG-ECRQSEDYES---FSCVCPTGWQ 374
Query: 313 VPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAG 371
G+ C+ ++ C + C A+C N + Y C C G+ G C+ D+D+C+
Sbjct: 375 --GQTCEV--DINECVLS-PCRHGASCQNTHGGYRCHCQAGYSGRN--CETDIDDCRP-- 425
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+ CH+ C + + C CL G+ + F +++EC + C A CT+
Sbjct: 426 ----NPCHNGGSCTDGINTAFCDCLPGF--RGTFCEEDINECASDP--CRNGANCTDCVD 477
Query: 432 SYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
SYTC C G+ G + + +CTE S C + CV+ F C C
Sbjct: 478 SYTCTCPAGFSGI-HCENNTPDCTESS--CFNGGTCVDGINSFTCLC 521
Score = 75.4 bits (177), Expect = 6e-13
Identities = 49/162 (30%), Positives = 69/162 (42%), Gaps = 16/162 (9%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGG--LHGHHCHS 380
+D C + H C TC++L Y C C +G Q G+ C+ +VD+C C +
Sbjct: 696 IDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQ--GVHCEINVDDCNPPVDPVSRSPKCFN 752
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRD 439
N CV+ VGGY C C G+ + C +V+EC N C + C CR
Sbjct: 753 NGTCVDQVGGYSCTCPPGFVGE---RCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRA 809
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSARCV---NIDGGFRCEC 478
G+ G C V +G C + C N GF C+C
Sbjct: 810 GH--TGRRCESVINGCKGK-PCKNGGTCAVASNTARGFICKC 848
Score = 68.9 bits (161), Expect = 5e-11
Identities = 78/300 (26%), Positives = 113/300 (37%), Gaps = 38/300 (12%)
Query: 199 DCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCL 258
DC+ + NG DG + C C+ G E D EC + G C C+
Sbjct: 422 DCRPNPCHNGGSCTDGI----NTAFCDCLPG-FRGTFCEEDINECASDPCRNGANCTDCV 476
Query: 259 RQ--CLLWGNLYE-HGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPG 315
C H E P +C E C +G T VD C P F+ G
Sbjct: 477 DSYTCTCPAGFSGIHCENNTP-DCTESSCFNGG---TCVD---GINSFTCLCPPGFT--G 527
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLH 374
C+ V+ C+ C TC + Y C C QG+ G CQ+ V C +
Sbjct: 528 SYCQH--DVNECD-SQPCLHGGTCQDGCGSYRCTCPQGYTGPN--CQNLVHWCDSSP--- 579
Query: 375 GHHCHSNTRCVNVVGGYVCQCLGGYTRK----DKFNCVEVDECEGNTHG--CHADAVCTN 428
C + +C Y C+C G+T +C + +G C +C +
Sbjct: 580 ---CKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVD 636
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
++ CRC+ GY G Y VDEC+ C + A C + GG+ C+C ++CS
Sbjct: 637 AGNTHHCRCQAGYTGS-YCEDLVDECSPSP--CQNGATCTDYLGGYSCKCVAGYHGVNCS 693
Score = 66.9 bits (156), Expect = 2e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 25/176 (14%)
Query: 305 CDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-D 363
C+ P F+ G C++ VD C C A C++ YTC C +G+ G C+ D
Sbjct: 26 CECPTGFT--GHLCQY--DVDEC-ASTPCKNGAKCLDGPNTYTCVCTEGY--TGTHCEVD 78
Query: 364 VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHA 422
+DEC CH + C + V + C C GYT +C ++EC ++ C
Sbjct: 79 IDECDP------DPCHYGS-CKDGVATFTCLCRPGYT---GHHCETNINEC--SSQPCRH 126
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C + +Y C C G G +++D+C S C S C++ G+ C C
Sbjct: 127 GGTCQDRDNAYLCFCLKGTTGPNCE-INLDDC--ASSPC-DSGTCLDKIDGYECAC 178
Score = 64.5 bits (150), Expect = 1e-09
Identities = 48/160 (30%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHS 380
P VD + C N TC++ Y+C C GF G+ C+ DV+EC +
Sbjct: 739 PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE--RCEGDVNECLS----NPCDARG 792
Query: 381 NTRCVNVVGGYVCQCLGGYTRKDKFNCVEV-DECEGN-THGCHADAVCTNTPGSYTCRCR 438
CV V + C+C G+T + C V + C+G AV +NT + C+C
Sbjct: 793 TQNCVQRVNDFHCECRAGHTGR---RCESVINGCKGKPCKNGGTCAVASNTARGFICKCP 849
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G+E G TC + D T GS C + C++ C C
Sbjct: 850 AGFE--GATCEN-DARTCGSLRCLNGGTCISGPRSPTCLC 886
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 14/116 (12%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
+ DEC + LH N RC++ + + C+C G+T +VDEC C
Sbjct: 2 NTDECASSPCLH------NGRCLDKINEFQCECPTGFT--GHLCQYDVDECASTP--CKN 51
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
A C + P +YTC C +GY G + + +DEC CH+ + C + F C C
Sbjct: 52 GAKCLDGPNTYTCVCTEGYTGT-HCEVDIDEC--DPDPCHYGS-CKDGVATFTCLC 103
>AL021578-2|CAI21077.1| 432|Homo sapiens matrilin 4 protein.
Length = 432
Score = 95.5 bits (227), Expect = 5e-19
Identities = 55/162 (33%), Positives = 76/162 (46%), Gaps = 18/162 (11%)
Query: 323 GVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCH 379
G D C GH C C+N + C CN G++ D +C +D C E G HG H
Sbjct: 25 GKDQCAEGGHGCQHQ--CVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAE--GTHGCEHH 80
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
CVN G Y C C G+ ++D+ +C +D C H C + C +TPG C CR
Sbjct: 81 ----CVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHE--CVSTPGGPRCHCR 134
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+G+ + DG +C D C H C +CV+ +RC C
Sbjct: 135 EGHDLQPDGRSCQVRDLCNGVDHGCEF--QCVSEGLSYRCLC 174
>AL021578-1|CAB46380.1| 622|Homo sapiens matrilin 4 protein.
Length = 622
Score = 95.5 bits (227), Expect = 5e-19
Identities = 55/162 (33%), Positives = 76/162 (46%), Gaps = 18/162 (11%)
Query: 323 GVDYC-NMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCH 379
G D C GH C C+N + C CN G++ D +C +D C E G HG H
Sbjct: 215 GKDQCAEGGHGCQHQ--CVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAE--GTHGCEHH 270
Query: 380 SNTRCVNVVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCR 438
CVN G Y C C G+ ++D+ +C +D C H C + C +TPG C CR
Sbjct: 271 ----CVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHE--CVSTPGGPRCHCR 324
Query: 439 DGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+G+ + DG +C D C H C +CV+ +RC C
Sbjct: 325 EGHDLQPDGRSCQVRDLCNGVDHGCEF--QCVSEGLSYRCLC 364
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/201 (29%), Positives = 85/201 (42%), Gaps = 16/201 (7%)
Query: 284 CHDGNMQCT-RVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNL 342
C + N C R R C Q + G+ C+ VD C G + + C+N
Sbjct: 143 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE---DVDECAAGLAQCAHG-CLNT 198
Query: 343 NTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ C C+ G++ DG C + E + ++ + C + G +C C GY
Sbjct: 199 QGSFKCVCHAGYELGADGRQCYRI-EMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYE 257
Query: 401 RK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
D+ C++VD+C + C VCTN PG Y C C GY DG C VDEC
Sbjct: 258 LDTDQRTCIDVDDCADSP--C-CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 314
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
C H C N+ G F+C C
Sbjct: 315 RGGCEH--HCTNLAGSFQCSC 333
Score = 84.2 bits (199), Expect = 1e-15
Identities = 66/209 (31%), Positives = 85/209 (40%), Gaps = 27/209 (12%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSCDENATCM 340
C +G Q V + R C P Q G C + P N SC C
Sbjct: 101 CALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSP---CANRNGSCMHR--CQ 155
Query: 341 NLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ C+C+ G+Q DG C+DVDEC A GL H C+N G + C C G
Sbjct: 156 VVRGLARCECHVGYQLAADGKACEDVDEC--AAGL-AQCAHG---CLNTQGSFKCVCHAG 209
Query: 399 YTR-KDKFNCVEVD-----ECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMH 450
Y D C ++ CE N GC C++T C C GYE D TC+
Sbjct: 210 YELGADGRQCYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTCID 267
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECF 479
VD+C + S C C N GG+ C C+
Sbjct: 268 VDDCAD-SPCCQQV--CTNNPGGYECGCY 293
Score = 71.7 bits (168), Expect = 7e-12
Identities = 62/212 (29%), Positives = 80/212 (37%), Gaps = 32/212 (15%)
Query: 281 ECVCHDGNMQ--CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENA 337
EC H+G Q C C C P + C ++ C +G+ C +
Sbjct: 59 ECRTHNGGCQHRCVNTPGSYLCE---CKPGFRLHTDSRTCL---AINSCALGNGGCQHHC 112
Query: 338 TCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQC 395
+ + T++ C+C GF Q DG C C G H RC V G C+C
Sbjct: 113 VQLTI-TRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH------RCQVVRGLARCEC 165
Query: 396 LGGY-TRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDGYE--GDGYTCMH- 450
GY D C +VDEC C H C NT GS+ C C GYE DG C
Sbjct: 166 HVGYQLAADGKACEDVDECAAGLAQCAHG---CLNTQGSFKCVCHAGYELGADGRQCYRI 222
Query: 451 ----VDECTEGSHTCHHSARCVNIDGGFRCEC 478
V+ C + C H C + G C C
Sbjct: 223 EMEIVNSCEANNGGCSHG--CSHTSAGPLCTC 252
Score = 68.1 bits (159), Expect = 9e-11
Identities = 40/119 (33%), Positives = 55/119 (46%), Gaps = 12/119 (10%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
DVDEC+ G H RCVN G Y+C+C G+ D C+ ++ C GC
Sbjct: 56 DVDECRTHNGGCQH------RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQ 109
Query: 422 ADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
V T + C+CR G+ + DG C+ C + +C H RC + G RCEC
Sbjct: 110 HHCV-QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCEC 165
Score = 68.1 bits (159), Expect = 9e-11
Identities = 38/106 (35%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C + + C C +G++ D TC DVD+C ++ C C N GGY C C
Sbjct: 241 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP------CCQQV-CTNNPGGYECGCY 293
Query: 397 GGYTRK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
GY D C +VDEC + GC CTN GS+ C C GY
Sbjct: 294 AGYRLSADGCGCEDVDECASSRGGCEHH--CTNLAGSFQCSCEAGY 337
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 11/95 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C VD C C + C N Y C C G++ DG C+DVDEC + G HH
Sbjct: 265 CIDVDDCADSPCCQQ--VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHH- 321
Query: 379 HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDE 412
C N+ G + C C GY +D+ C ++E
Sbjct: 322 -----CTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 351
Score = 46.0 bits (104), Expect = 4e-04
Identities = 49/175 (28%), Positives = 60/175 (34%), Gaps = 26/175 (14%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
C SC A C ++ C+C GF G G C+ C G +G C C+N
Sbjct: 937 CAQRCSCPPGAACHHVTG--ACRCPPGFTGSG--CE--QGCPP--GRYGPGCEQLCGCLN 988
Query: 387 VVGGY------VCQCLGGYTRKD-KFNCVEVDECEGNTH--GCHADAVCTNTPGSYTCRC 437
GG C+C G+ D C + TH GC A C G TC C
Sbjct: 989 --GGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLC 1044
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGR 492
G G C C H+ C N GG C +C W GR
Sbjct: 1045 PPGRA--GVRCERGCPQNRFGVGCEHTCSCRN--GGL-CHASNGSCSCGLGWTGR 1094
Score = 44.8 bits (101), Expect = 0.001
Identities = 62/246 (25%), Positives = 91/246 (36%), Gaps = 39/246 (15%)
Query: 273 RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP-GECCKFCPGVDYCNMGH 331
R+ P C C +G C CP + P G C V C G
Sbjct: 975 RYGPGCEQLCGCLNGG-SCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGA 1033
Query: 332 SCDE-NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
+CD TC+ + +C +G + G+ C+ C+ GGL CH++
Sbjct: 1034 ACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN-GGL----CHASNGS---- 1084
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHG--CHADAVCTNT----PGSYTCRCRDGYE 442
C C G+T + +C E+ C +G CH + C N P + TCRC G+
Sbjct: 1085 ----CSCGLGWTGR---HC-EL-ACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY 1135
Query: 443 G-------DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
G G TC ++D C G + C + GG C+ + C + G
Sbjct: 1136 GQACEHRRSGATC-NLD-CRRGQFGPSCTLHC-DCGGGADCDPVSGQCHCVDGYMGPTCR 1192
Query: 496 EGATWR 501
EG R
Sbjct: 1193 EGGPLR 1198
Score = 40.7 bits (91), Expect = 0.016
Identities = 81/308 (26%), Positives = 114/308 (37%), Gaps = 66/308 (21%)
Query: 195 LEQCDCQKS---CYSNGTVHADGATWQRDCN-RCSCVHGEITCRPVECDRAECKNPVLHP 250
L+ CDC + N T D T+ ++C+ CSC +G TC V C+ P P
Sbjct: 432 LDGCDCPEGWTGLICNETCPPD--TFGKNCSFSCSCQNGG-TCDSVT---GACRCP---P 482
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQ 309
G C C + + K C + C C + +C R+ AC CDP
Sbjct: 483 GVSGTNCEDGC---------PKGYYGKHCRKKCNCANRG-RCHRLYG--ACL---CDP-- 525
Query: 310 QFSVPGECCKF-CPGVDYCNMGHSCDENATCMNLNTKY------TCKCNQGFQGDGLTCQ 362
+ G C CP + G C E C+ +T+ +C C GF+G+ CQ
Sbjct: 526 --GLYGRFCHLTCPPWAF---GPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE--RCQ 578
Query: 363 DVDECQEA----GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTH 418
EC+ G C C +V G +C G+ +D C + EC T
Sbjct: 579 A--ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGED---CGQ--ECPVGTF 631
Query: 419 G--CHADAVCTNTPG---SYTCRCRDGYEGDGYTCMHVDE-----CTEGSHTCHHSARCV 468
G C + C P + CRC G G+ + C E C H+ARC
Sbjct: 632 GVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCD 691
Query: 469 NIDGGFRC 476
G C
Sbjct: 692 PETGACLC 699
Score = 39.9 bits (89), Expect = 0.028
Identities = 57/220 (25%), Positives = 69/220 (31%), Gaps = 29/220 (13%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCD-ENA 337
C CH QC R P D P+ G C + CP C CD E
Sbjct: 641 CGGAPCHGVTGQC-RCPPGRTGEDCEADCPEGRWGLG-CQEICPA---CQHAARCDPETG 695
Query: 338 TCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ- 394
C+ L +C G +CQ C G H H + C G+ CQ
Sbjct: 696 ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDG--HCHPATGHCSCAPGWTGFSCQR 753
Query: 395 -CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCM-- 449
C G+ D C C C DA+ S C C GY G C
Sbjct: 754 ACDTGHWGPD---CSHPCNCSAGHGSC--DAI------SGLCLCEAGYVGPRCEQQCPQG 802
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCECFTEN--CELSC 487
H E C H A C ++ G C CE +C
Sbjct: 803 HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHAC 842
Score = 36.3 bits (80), Expect = 0.34
Identities = 51/184 (27%), Positives = 68/184 (36%), Gaps = 33/184 (17%)
Query: 327 CNMGH-SCDE-NATCM----NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC-H 379
C+ GH SCD + C+ + + +C QG G G C+ +CQ HG C H
Sbjct: 770 CSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPG--CEQRCQCQ-----HGAACDH 822
Query: 380 SNTRCVNVVG--GYVCQ--CLGGYTRKD---KFNCVEVDECEGNTHGCHADAVCTNTPGS 432
+ C G G C+ C G+ D NC C+ C A +
Sbjct: 823 VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA 882
Query: 433 YTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDG--GFRCE--C----FTENCE 484
C RD G C H C G H+ RC+ G G +C+ C F E C
Sbjct: 883 EKCLPRDVRAG----CRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACA 938
Query: 485 LSCS 488
CS
Sbjct: 939 QRCS 942
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/201 (29%), Positives = 85/201 (42%), Gaps = 16/201 (7%)
Query: 284 CHDGNMQCT-RVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNL 342
C + N C R R C Q + G+ C+ VD C G + + C+N
Sbjct: 143 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE---DVDECAAGLAQCAHG-CLNT 198
Query: 343 NTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ C C+ G++ DG C + E + ++ + C + G +C C GY
Sbjct: 199 QGSFKCVCHAGYELGADGRQCYRI-EMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYE 257
Query: 401 RK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
D+ C++VD+C + C VCTN PG Y C C GY DG C VDEC
Sbjct: 258 LDTDQRTCIDVDDCADSP--C-CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 314
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
C H C N+ G F+C C
Sbjct: 315 RGGCEH--HCTNLAGSFQCSC 333
Score = 84.2 bits (199), Expect = 1e-15
Identities = 66/209 (31%), Positives = 85/209 (40%), Gaps = 27/209 (12%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSCDENATCM 340
C +G Q V + R C P Q G C + P N SC C
Sbjct: 101 CALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSP---CANRNGSCMHR--CQ 155
Query: 341 NLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ C+C+ G+Q DG C+DVDEC A GL H C+N G + C C G
Sbjct: 156 VVRGLARCECHVGYQLAADGKACEDVDEC--AAGL-AQCAHG---CLNTQGSFKCVCHAG 209
Query: 399 YTR-KDKFNCVEVD-----ECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMH 450
Y D C ++ CE N GC C++T C C GYE D TC+
Sbjct: 210 YELGADGRQCYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTCID 267
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECF 479
VD+C + S C C N GG+ C C+
Sbjct: 268 VDDCAD-SPCCQQV--CTNNPGGYECGCY 293
Score = 71.7 bits (168), Expect = 7e-12
Identities = 62/212 (29%), Positives = 80/212 (37%), Gaps = 32/212 (15%)
Query: 281 ECVCHDGNMQ--CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENA 337
EC H+G Q C C C P + C ++ C +G+ C +
Sbjct: 59 ECRTHNGGCQHRCVNTPGSYLCE---CKPGFRLHTDSRTCL---AINSCALGNGGCQHHC 112
Query: 338 TCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQC 395
+ + T++ C+C GF Q DG C C G H RC V G C+C
Sbjct: 113 VQLTI-TRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH------RCQVVRGLARCEC 165
Query: 396 LGGY-TRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDGYE--GDGYTCMH- 450
GY D C +VDEC C H C NT GS+ C C GYE DG C
Sbjct: 166 HVGYQLAADGKACEDVDECAAGLAQCAHG---CLNTQGSFKCVCHAGYELGADGRQCYRI 222
Query: 451 ----VDECTEGSHTCHHSARCVNIDGGFRCEC 478
V+ C + C H C + G C C
Sbjct: 223 EMEIVNSCEANNGGCSHG--CSHTSAGPLCTC 252
Score = 68.1 bits (159), Expect = 9e-11
Identities = 40/119 (33%), Positives = 55/119 (46%), Gaps = 12/119 (10%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
DVDEC+ G H RCVN G Y+C+C G+ D C+ ++ C GC
Sbjct: 56 DVDECRTHNGGCQH------RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQ 109
Query: 422 ADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
V T + C+CR G+ + DG C+ C + +C H RC + G RCEC
Sbjct: 110 HHCV-QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCEC 165
Score = 68.1 bits (159), Expect = 9e-11
Identities = 38/106 (35%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C + + C C +G++ D TC DVD+C ++ C C N GGY C C
Sbjct: 241 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP------CCQQV-CTNNPGGYECGCY 293
Query: 397 GGYTRK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
GY D C +VDEC + GC CTN GS+ C C GY
Sbjct: 294 AGYRLSADGCGCEDVDECASSRGGCEHH--CTNLAGSFQCSCEAGY 337
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 11/95 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C VD C C + C N Y C C G++ DG C+DVDEC + G HH
Sbjct: 265 CIDVDDCADSPCCQQ--VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHH- 321
Query: 379 HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDE 412
C N+ G + C C GY +D+ C ++E
Sbjct: 322 -----CTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 351
Score = 46.0 bits (104), Expect = 4e-04
Identities = 49/175 (28%), Positives = 60/175 (34%), Gaps = 26/175 (14%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
C SC A C ++ C+C GF G G C+ C G +G C C+N
Sbjct: 937 CAQRCSCPPGAACHHVTG--ACRCPPGFTGSG--CE--QGCPP--GRYGPGCEQLCGCLN 988
Query: 387 VVGGY------VCQCLGGYTRKD-KFNCVEVDECEGNTH--GCHADAVCTNTPGSYTCRC 437
GG C+C G+ D C + TH GC A C G TC C
Sbjct: 989 --GGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLC 1044
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGR 492
G G C C H+ C N GG C +C W GR
Sbjct: 1045 PPGRA--GVRCERGCPQNRFGVGCEHTCSCRN--GGL-CHASNGSCSCGLGWTGR 1094
Score = 44.8 bits (101), Expect = 0.001
Identities = 62/246 (25%), Positives = 91/246 (36%), Gaps = 39/246 (15%)
Query: 273 RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP-GECCKFCPGVDYCNMGH 331
R+ P C C +G C CP + P G C V C G
Sbjct: 975 RYGPGCEQLCGCLNGG-SCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGA 1033
Query: 332 SCDE-NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
+CD TC+ + +C +G + G+ C+ C+ GGL CH++
Sbjct: 1034 ACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN-GGL----CHASNGS---- 1084
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHG--CHADAVCTNT----PGSYTCRCRDGYE 442
C C G+T + +C E+ C +G CH + C N P + TCRC G+
Sbjct: 1085 ----CSCGLGWTGR---HC-EL-ACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY 1135
Query: 443 G-------DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
G G TC ++D C G + C + GG C+ + C + G
Sbjct: 1136 GQACEHRRSGATC-NLD-CRRGQFGPSCTLHC-DCGGGADCDPVSGQCHCVDGYMGPTCR 1192
Query: 496 EGATWR 501
EG R
Sbjct: 1193 EGGPLR 1198
Score = 40.7 bits (91), Expect = 0.016
Identities = 81/308 (26%), Positives = 114/308 (37%), Gaps = 66/308 (21%)
Query: 195 LEQCDCQKS---CYSNGTVHADGATWQRDCN-RCSCVHGEITCRPVECDRAECKNPVLHP 250
L+ CDC + N T D T+ ++C+ CSC +G TC V C+ P P
Sbjct: 432 LDGCDCPEGWTGLICNETCPPD--TFGKNCSFSCSCQNGG-TCDSVT---GACRCP---P 482
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQ 309
G C C + + K C + C C + +C R+ AC CDP
Sbjct: 483 GVSGTNCEDGC---------PKGYYGKHCRKKCNCANRG-RCHRLYG--ACL---CDP-- 525
Query: 310 QFSVPGECCKF-CPGVDYCNMGHSCDENATCMNLNTKY------TCKCNQGFQGDGLTCQ 362
+ G C CP + G C E C+ +T+ +C C GF+G+ CQ
Sbjct: 526 --GLYGRFCHLTCPPWAF---GPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE--RCQ 578
Query: 363 DVDECQEA----GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTH 418
EC+ G C C +V G +C G+ +D C + EC T
Sbjct: 579 A--ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGED---CGQ--ECPVGTF 631
Query: 419 G--CHADAVCTNTPG---SYTCRCRDGYEGDGYTCMHVDE-----CTEGSHTCHHSARCV 468
G C + C P + CRC G G+ + C E C H+ARC
Sbjct: 632 GVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCD 691
Query: 469 NIDGGFRC 476
G C
Sbjct: 692 PETGACLC 699
Score = 39.9 bits (89), Expect = 0.028
Identities = 57/220 (25%), Positives = 69/220 (31%), Gaps = 29/220 (13%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCD-ENA 337
C CH QC R P D P+ G C + CP C CD E
Sbjct: 641 CGGAPCHGVTGQC-RCPPGRTGEDCEADCPEGRWGLG-CQEICPA---CQHAARCDPETG 695
Query: 338 TCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ- 394
C+ L +C G +CQ C G H H + C G+ CQ
Sbjct: 696 ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDG--HCHPATGHCSCAPGWTGFSCQR 753
Query: 395 -CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCM-- 449
C G+ D C C C DA+ S C C GY G C
Sbjct: 754 ACDTGHWGPD---CSHPCNCSAGHGSC--DAI------SGLCLCEAGYVGPRCEQQCPQG 802
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCECFTEN--CELSC 487
H E C H A C ++ G C CE +C
Sbjct: 803 HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHAC 842
Score = 36.3 bits (80), Expect = 0.34
Identities = 51/184 (27%), Positives = 68/184 (36%), Gaps = 33/184 (17%)
Query: 327 CNMGH-SCDE-NATCM----NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC-H 379
C+ GH SCD + C+ + + +C QG G G C+ +CQ HG C H
Sbjct: 770 CSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPG--CEQRCQCQ-----HGAACDH 822
Query: 380 SNTRCVNVVG--GYVCQ--CLGGYTRKD---KFNCVEVDECEGNTHGCHADAVCTNTPGS 432
+ C G G C+ C G+ D NC C+ C A +
Sbjct: 823 VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA 882
Query: 433 YTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDG--GFRCE--C----FTENCE 484
C RD G C H C G H+ RC+ G G +C+ C F E C
Sbjct: 883 EKCLPRDVRAG----CRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACA 938
Query: 485 LSCS 488
CS
Sbjct: 939 QRCS 942
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/201 (29%), Positives = 85/201 (42%), Gaps = 16/201 (7%)
Query: 284 CHDGNMQCT-RVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNL 342
C + N C R R C Q + G+ C+ VD C G + + C+N
Sbjct: 323 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE---DVDECAAGLAQCAHG-CLNT 378
Query: 343 NTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ C C+ G++ DG C + E + ++ + C + G +C C GY
Sbjct: 379 QGSFKCVCHAGYELGADGRQCYRI-EMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYE 437
Query: 401 RK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
D+ C++VD+C + C VCTN PG Y C C GY DG C VDEC
Sbjct: 438 LDTDQRTCIDVDDCADSP--C-CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 494
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
C H C N+ G F+C C
Sbjct: 495 RGGCEH--HCTNLAGSFQCSC 513
Score = 84.2 bits (199), Expect = 1e-15
Identities = 66/209 (31%), Positives = 85/209 (40%), Gaps = 27/209 (12%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSCDENATCM 340
C +G Q V + R C P Q G C + P N SC C
Sbjct: 281 CALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSP---CANRNGSCMHR--CQ 335
Query: 341 NLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ C+C+ G+Q DG C+DVDEC A GL H C+N G + C C G
Sbjct: 336 VVRGLARCECHVGYQLAADGKACEDVDEC--AAGL-AQCAHG---CLNTQGSFKCVCHAG 389
Query: 399 YTR-KDKFNCVEVD-----ECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMH 450
Y D C ++ CE N GC C++T C C GYE D TC+
Sbjct: 390 YELGADGRQCYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTCID 447
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECF 479
VD+C + S C C N GG+ C C+
Sbjct: 448 VDDCAD-SPCCQQV--CTNNPGGYECGCY 473
Score = 79.0 bits (186), Expect = 5e-14
Identities = 52/156 (33%), Positives = 70/156 (44%), Gaps = 17/156 (10%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCV 385
C+ G C C+ + C C GFQG CQ DVDEC+ G H RCV
Sbjct: 203 CSAG-LCFHGGRCVP-GSAQPCHCPPGFQGP--RCQYDVDECRTHNGGCQH------RCV 252
Query: 386 NVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--E 442
N G Y+C+C G+ D C+ ++ C GC V T + C+CR G+ +
Sbjct: 253 NTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCV-QLTITRHRCQCRPGFQLQ 311
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
DG C+ C + +C H RC + G RCEC
Sbjct: 312 EDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCEC 345
Score = 76.6 bits (180), Expect = 3e-13
Identities = 73/256 (28%), Positives = 94/256 (36%), Gaps = 36/256 (14%)
Query: 238 CDRAECKNPV-LHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQ--CTRV 294
C AEC + H G C P + C G R + EC H+G Q C
Sbjct: 198 CLSAECSAGLCFHGGRCVPGSAQPCHCPPGF--QGPR-CQYDVDECRTHNGGCQHRCVNT 254
Query: 295 DPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENATCMNLNTKYTCKCNQG 353
C C P + C ++ C +G+ C + + + T++ C+C G
Sbjct: 255 PGSYLCE---CKPGFRLHTDSRTCL---AINSCALGNGGCQHHCVQLTI-TRHRCQCRPG 307
Query: 354 F--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEV 410
F Q DG C C G H RC V G C+C GY D C +V
Sbjct: 308 FQLQEDGRHCVRRSPCANRNGSCMH------RCQVVRGLARCECHVGYQLAADGKACEDV 361
Query: 411 DECEGNTHGC-HADAVCTNTPGSYTCRCRDGYE--GDGYTCMH-----VDECTEGSHTCH 462
DEC C H C NT GS+ C C GYE DG C V+ C + C
Sbjct: 362 DECAAGLAQCAHG---CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCS 418
Query: 463 HSARCVNIDGGFRCEC 478
H C + G C C
Sbjct: 419 HG--CSHTSAGPLCTC 432
Score = 68.1 bits (159), Expect = 9e-11
Identities = 38/106 (35%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C + + C C +G++ D TC DVD+C ++ C C N GGY C C
Sbjct: 421 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP------CCQQV-CTNNPGGYECGCY 473
Query: 397 GGYTRK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
GY D C +VDEC + GC CTN GS+ C C GY
Sbjct: 474 AGYRLSADGCGCEDVDECASSRGGCEHH--CTNLAGSFQCSCEAGY 517
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 11/95 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C VD C C + C N Y C C G++ DG C+DVDEC + G HH
Sbjct: 445 CIDVDDCADSPCCQQ--VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHH- 501
Query: 379 HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDE 412
C N+ G + C C GY +D+ C ++E
Sbjct: 502 -----CTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 531
Score = 48.0 bits (109), Expect = 1e-04
Identities = 75/298 (25%), Positives = 107/298 (35%), Gaps = 53/298 (17%)
Query: 198 CDCQKSCYSNGTVHA-DGATWQRDCNR-CSCVHGEITCRPVECDRAECKNPVLHPGECCP 255
C C +G A ++ DC + C C C P C + G P
Sbjct: 1222 CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPAT---GTCSCAAGYHG---P 1275
Query: 256 TCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP- 314
+C ++C R+ P C C +G C CP + P
Sbjct: 1276 SCQQRC--------PPGRYGPGCEQLCGCLNGG-SCDAATGACRCPTGFLGTDCNLTCPQ 1326
Query: 315 GECCKFCPGVDYCNMGHSCDE-NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAG 371
G C V C G +CD TC+ + +C +G + G+ C+ C+ G
Sbjct: 1327 GRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN-G 1385
Query: 372 GLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG--CHADAVCTNT 429
GL CH++ C C G+T + +C E+ C +G CH + C N
Sbjct: 1386 GL----CHASNGS--------CSCGLGWTGR---HC-EL-ACPPGRYGAACHLECSCHNN 1428
Query: 430 ----PGSYTCRCRDGYEGDG--YTC---MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
P + TCRC G+ G + C H C +G C H A C I G RC C
Sbjct: 1429 STCEPATGTCRCGPGFYGQACEHPCPPGFHGAGC-QGLCWCQHGAPCDPISG--RCLC 1483
Score = 46.8 bits (106), Expect = 2e-04
Identities = 80/311 (25%), Positives = 106/311 (34%), Gaps = 73/311 (23%)
Query: 200 CQKSCYSNGTVHADGATWQRDCNR-CSCVHGEITCRPVECDRAECKNPVLHPGECCPTCL 258
CQ++C D W DC+ C+C G +C + C + G P C
Sbjct: 931 CQRAC--------DTGHWGPDCSHPCNCSAGHGSCDAIS---GLC---LCEAGYVGPRCE 976
Query: 259 RQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECC 318
+QC G F P C C G C V CP G C
Sbjct: 977 QQC-------PQGH-FGPGCEQLCQCQHG-AACDHVSGACTCPA---------GWRGTFC 1018
Query: 319 KF-CP----GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGL 373
+ CP G+D C +C A C +N +C C G +G C E
Sbjct: 1019 EHACPAGFFGLD-CRSACNCTAGAACDAVNG--SCLCPAGRRGP--------RCAETCPA 1067
Query: 374 H--GHHCHSNTRCVN-----VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG--CHADA 424
H GH+C C N V G C C G+ +C++ C +G C
Sbjct: 1068 HTYGHNCSQACACFNGASCDPVHGQ-CHCAPGWMGP---SCLQA--CPAGLYGDNCRHSC 1121
Query: 425 VCTN----TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFT 480
+C N P S C C +G+ G C + C HS C+N GG C+ T
Sbjct: 1122 LCQNGGTCDPVSGHCACPEGWA--GLACEKECLPRDVRAGCRHSGGCLN--GGL-CDPHT 1176
Query: 481 ENCELSCSWQG 491
C W G
Sbjct: 1177 GRCLCPAGWTG 1187
Score = 40.7 bits (91), Expect = 0.016
Identities = 81/308 (26%), Positives = 114/308 (37%), Gaps = 66/308 (21%)
Query: 195 LEQCDCQKS---CYSNGTVHADGATWQRDCN-RCSCVHGEITCRPVECDRAECKNPVLHP 250
L+ CDC + N T D T+ ++C+ CSC +G TC V C+ P P
Sbjct: 612 LDGCDCPEGWTGLICNETCPPD--TFGKNCSFSCSCQNGG-TCDSVT---GACRCP---P 662
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQ 309
G C C + + K C + C C + +C R+ AC CDP
Sbjct: 663 GVSGTNCEDGC---------PKGYYGKHCRKKCNCANRG-RCHRLYG--ACL---CDP-- 705
Query: 310 QFSVPGECCKF-CPGVDYCNMGHSCDENATCMNLNTKY------TCKCNQGFQGDGLTCQ 362
+ G C CP + G C E C+ +T+ +C C GF+G+ CQ
Sbjct: 706 --GLYGRFCHLTCPPWAF---GPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE--RCQ 758
Query: 363 DVDECQEA----GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTH 418
EC+ G C C +V G +C G+ +D C + EC T
Sbjct: 759 A--ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGED---CGQ--ECPVGTF 811
Query: 419 G--CHADAVCTNTPG---SYTCRCRDGYEGDGYTCMHVDE-----CTEGSHTCHHSARCV 468
G C + C P + CRC G G+ + C E C H+ARC
Sbjct: 812 GVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCD 871
Query: 469 NIDGGFRC 476
G C
Sbjct: 872 PETGACLC 879
Score = 39.5 bits (88), Expect = 0.037
Identities = 57/220 (25%), Positives = 69/220 (31%), Gaps = 29/220 (13%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCD-ENA 337
C CH QC R P D P+ G C + CP C CD E
Sbjct: 821 CGGAPCHGVTGQC-RCPPGRTGEDCEADCPEGRWGLG-CQEICPA---CQHAARCDPETG 875
Query: 338 TCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ- 394
C+ L +C G +CQ C G H H + C G+ CQ
Sbjct: 876 ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDG--HCHPATGHCSCAPGWTGFSCQR 933
Query: 395 -CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCM-- 449
C G+ D C C C DA+ S C C GY G C
Sbjct: 934 ACDTGHWGPD---CSHPCNCSAGHGSC--DAI------SGLCLCEAGYVGPRCEQQCPQG 982
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCECFTEN--CELSC 487
H E C H A C ++ G C CE +C
Sbjct: 983 HFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHAC 1022
Score = 33.5 bits (73), Expect = 2.4
Identities = 44/167 (26%), Positives = 53/167 (31%), Gaps = 17/167 (10%)
Query: 281 ECVCHDGNMQCTRVDPELAC-PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATC 339
EC CH+ N C C P + PG C G+ +C G CD +
Sbjct: 1422 ECSCHN-NSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISG- 1479
Query: 340 MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAG-GLHGH-HCHSNTRCVNVVGGYVCQCLG 397
C C GF G C+ E G G H C C V G +C C
Sbjct: 1480 -------RCLCPAGFHGH--FCERGCEPGSFGEGCHQRCDCDGGAPCDPVTG--LCLCPP 1528
Query: 398 GYTRKD-KFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
G + +C T C P S C C DGY G
Sbjct: 1529 GRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMG 1575
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/201 (29%), Positives = 85/201 (42%), Gaps = 16/201 (7%)
Query: 284 CHDGNMQCT-RVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNL 342
C + N C R R C Q + G+ C+ VD C G + + C+N
Sbjct: 160 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE---DVDECAAGLAQCAHG-CLNT 215
Query: 343 NTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ C C+ G++ DG C + E + ++ + C + G +C C GY
Sbjct: 216 QGSFKCVCHAGYELGADGRQCYRI-EMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYE 274
Query: 401 RK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEG 457
D+ C++VD+C + C VCTN PG Y C C GY DG C VDEC
Sbjct: 275 LDTDQRTCIDVDDCADSP--C-CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 331
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
C H C N+ G F+C C
Sbjct: 332 RGGCEH--HCTNLAGSFQCSC 350
Score = 84.2 bits (199), Expect = 1e-15
Identities = 66/209 (31%), Positives = 85/209 (40%), Gaps = 27/209 (12%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGE-CCKFCPGVDYCNMGHSCDENATCM 340
C +G Q V + R C P Q G C + P N SC C
Sbjct: 118 CALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSP---CANRNGSCMHR--CQ 172
Query: 341 NLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGG 398
+ C+C+ G+Q DG C+DVDEC A GL H C+N G + C C G
Sbjct: 173 VVRGLARCECHVGYQLAADGKACEDVDEC--AAGL-AQCAHG---CLNTQGSFKCVCHAG 226
Query: 399 YTR-KDKFNCVEVD-----ECEGNTHGCHADAVCTNTPGSYTCRCRDGYE--GDGYTCMH 450
Y D C ++ CE N GC C++T C C GYE D TC+
Sbjct: 227 YELGADGRQCYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTCPRGYELDTDQRTCID 284
Query: 451 VDECTEGSHTCHHSARCVNIDGGFRCECF 479
VD+C + S C C N GG+ C C+
Sbjct: 285 VDDCAD-SPCCQQV--CTNNPGGYECGCY 310
Score = 71.7 bits (168), Expect = 7e-12
Identities = 62/212 (29%), Positives = 80/212 (37%), Gaps = 32/212 (15%)
Query: 281 ECVCHDGNMQ--CTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHS-CDENA 337
EC H+G Q C C C P + C ++ C +G+ C +
Sbjct: 76 ECRTHNGGCQHRCVNTPGSYLCE---CKPGFRLHTDSRTCL---AINSCALGNGGCQHHC 129
Query: 338 TCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQC 395
+ + T++ C+C GF Q DG C C G H RC V G C+C
Sbjct: 130 VQLTI-TRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH------RCQVVRGLARCEC 182
Query: 396 LGGY-TRKDKFNCVEVDECEGNTHGC-HADAVCTNTPGSYTCRCRDGYE--GDGYTCMH- 450
GY D C +VDEC C H C NT GS+ C C GYE DG C
Sbjct: 183 HVGYQLAADGKACEDVDECAAGLAQCAHG---CLNTQGSFKCVCHAGYELGADGRQCYRI 239
Query: 451 ----VDECTEGSHTCHHSARCVNIDGGFRCEC 478
V+ C + C H C + G C C
Sbjct: 240 EMEIVNSCEANNGGCSHG--CSHTSAGPLCTC 269
Score = 68.1 bits (159), Expect = 9e-11
Identities = 40/119 (33%), Positives = 55/119 (46%), Gaps = 12/119 (10%)
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDECEGNTHGCH 421
DVDEC+ G H RCVN G Y+C+C G+ D C+ ++ C GC
Sbjct: 73 DVDECRTHNGGCQH------RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQ 126
Query: 422 ADAVCTNTPGSYTCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
V T + C+CR G+ + DG C+ C + +C H RC + G RCEC
Sbjct: 127 HHCV-QLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH--RCQVVRGLARCEC 182
Score = 68.1 bits (159), Expect = 9e-11
Identities = 38/106 (35%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 339 CMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
C + + C C +G++ D TC DVD+C ++ C C N GGY C C
Sbjct: 258 CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSP------CCQQV-CTNNPGGYECGCY 310
Query: 397 GGYTRK-DKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGY 441
GY D C +VDEC + GC CTN GS+ C C GY
Sbjct: 311 AGYRLSADGCGCEDVDECASSRGGCEHH--CTNLAGSFQCSCEAGY 354
Score = 56.8 bits (131), Expect = 2e-07
Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 11/95 (11%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQ--GDGLTCQDVDECQEAGGLHGHHC 378
C VD C C + C N Y C C G++ DG C+DVDEC + G HH
Sbjct: 282 CIDVDDCADSPCCQQ--VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHH- 338
Query: 379 HSNTRCVNVVGGYVCQCLGGY-TRKDKFNCVEVDE 412
C N+ G + C C GY +D+ C ++E
Sbjct: 339 -----CTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 368
Score = 45.2 bits (102), Expect = 7e-04
Identities = 49/175 (28%), Positives = 60/175 (34%), Gaps = 26/175 (14%)
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
C SC A C ++ C+C GF G G C+ C G +G C C+N
Sbjct: 954 CAQRCSCPPAAACHHVTG--ACRCPPGFTGSG--CE--QGCPP--GRYGPGCEQLCGCLN 1005
Query: 387 VVGGY------VCQCLGGYTRKD-KFNCVEVDECEGNTH--GCHADAVCTNTPGSYTCRC 437
GG C+C G+ D C + TH GC A C G TC C
Sbjct: 1006 --GGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLC 1061
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGR 492
G G C C H+ C N GG C +C W GR
Sbjct: 1062 PPGRA--GVRCERGCPQNRFGVGCEHTCSCRN--GGL-CHASNGSCSCGLGWTGR 1111
Score = 44.8 bits (101), Expect = 0.001
Identities = 62/246 (25%), Positives = 91/246 (36%), Gaps = 39/246 (15%)
Query: 273 RFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP-GECCKFCPGVDYCNMGH 331
R+ P C C +G C CP + P G C V C G
Sbjct: 992 RYGPGCEQLCGCLNGG-SCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGA 1050
Query: 332 SCDE-NATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
+CD TC+ + +C +G + G+ C+ C+ GGL CH++
Sbjct: 1051 ACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRN-GGL----CHASNGS---- 1101
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHG--CHADAVCTNT----PGSYTCRCRDGYE 442
C C G+T + +C E+ C +G CH + C N P + TCRC G+
Sbjct: 1102 ----CSCGLGWTGR---HC-EL-ACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY 1152
Query: 443 G-------DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVS 495
G G TC ++D C G + C + GG C+ + C + G
Sbjct: 1153 GQACEHRRSGATC-NLD-CRRGQFGPSCTLHC-DCGGGADCDPVSGQCHCVDGYMGPTCR 1209
Query: 496 EGATWR 501
EG R
Sbjct: 1210 EGGPLR 1215
Score = 40.7 bits (91), Expect = 0.016
Identities = 81/308 (26%), Positives = 114/308 (37%), Gaps = 66/308 (21%)
Query: 195 LEQCDCQKS---CYSNGTVHADGATWQRDCN-RCSCVHGEITCRPVECDRAECKNPVLHP 250
L+ CDC + N T D T+ ++C+ CSC +G TC V C+ P P
Sbjct: 449 LDGCDCPEGWTGLICNETCPPD--TFGKNCSFSCSCQNGG-TCDSVT---GACRCP---P 499
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAE-CVCHDGNMQCTRVDPELACPRLPCDPPQ 309
G C C + + K C + C C + +C R+ AC CDP
Sbjct: 500 GVSGTNCEDGC---------PKGYYGKHCRKKCNCANRG-RCHRLYG--ACL---CDP-- 542
Query: 310 QFSVPGECCKF-CPGVDYCNMGHSCDENATCMNLNTKY------TCKCNQGFQGDGLTCQ 362
+ G C CP + G C E C+ +T+ +C C GF+G+ CQ
Sbjct: 543 --GLYGRFCHLTCPPWAF---GPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE--RCQ 595
Query: 363 DVDECQEA----GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTH 418
EC+ G C C +V G +C G+ +D C + EC T
Sbjct: 596 A--ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGED---CGQ--ECPVGTF 648
Query: 419 G--CHADAVCTNTPG---SYTCRCRDGYEGDGYTCMHVDE-----CTEGSHTCHHSARCV 468
G C + C P + CRC G G+ + C E C H+ARC
Sbjct: 649 GVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCD 708
Query: 469 NIDGGFRC 476
G C
Sbjct: 709 PETGACLC 716
Score = 39.5 bits (88), Expect = 0.037
Identities = 57/220 (25%), Positives = 69/220 (31%), Gaps = 29/220 (13%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCD-ENA 337
C CH QC R P D P+ G C + CP C CD E
Sbjct: 658 CGGAPCHGVTGQC-RCPPGRTGEDCEADCPEGRWGLG-CQEICPA---CQHAARCDPETG 712
Query: 338 TCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ- 394
C+ L +C G +CQ C G H H + C G+ CQ
Sbjct: 713 ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDG--HCHPATGHCSCAPGWTGFSCQR 770
Query: 395 -CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG--YTCM-- 449
C G+ D C C C DA+ S C C GY G C
Sbjct: 771 ACDTGHWGPD---CSHPCNCSAGHGSC--DAI------SGLCLCEAGYVGPRCEQQCPQG 819
Query: 450 HVDECTEGSHTCHHSARCVNIDGGFRCECFTEN--CELSC 487
H E C H A C ++ G C CE +C
Sbjct: 820 HFGPGCEQLCQCQHGAACDHVSGACTCPAGWRGTFCEHAC 859
Score = 37.9 bits (84), Expect = 0.11
Identities = 51/184 (27%), Positives = 69/184 (37%), Gaps = 33/184 (17%)
Query: 327 CNMGH-SCDE-NATCM----NLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC-H 379
C+ GH SCD + C+ + + +C QG G G C+ + +CQ HG C H
Sbjct: 787 CSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPG--CEQLCQCQ-----HGAACDH 839
Query: 380 SNTRCVNVVG--GYVCQ--CLGGYTRKD---KFNCVEVDECEGNTHGCHADAVCTNTPGS 432
+ C G G C+ C G+ D NC C+ C A +
Sbjct: 840 VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA 899
Query: 433 YTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDG--GFRCE--C----FTENCE 484
C RD G C H C G H+ RC+ G G +C+ C F E C
Sbjct: 900 EKCLPRDVRAG----CRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACA 955
Query: 485 LSCS 488
CS
Sbjct: 956 QRCS 959
>Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein.
Length = 676
Score = 94.7 bits (225), Expect = 9e-19
Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 16/152 (10%)
Query: 333 CDENA--TCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVG 389
C+E+ +C + +TC C G+QG+ C+ D++EC++ ++G C + C N G
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGG-C--SQICDNTPG 180
Query: 390 GYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GY 446
Y C C G+ +K +C +VDEC C AVC N PG + C C +GY +
Sbjct: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSK 239
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +DEC+E + C + CVN GG+ C C
Sbjct: 240 SCEDIDECSE--NMC--AQLCVNYPGGYTCYC 267
Score = 55.2 bits (127), Expect = 7e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C VD C++ S A C N+ + C+C +G++ + +C+D+DEC E +
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE------N 250
Query: 377 HCHSNTRCVNVVGGYVCQCLG--GY-TRKDKFNCVEVDEC 413
C CVN GGY C C G G+ +D+ +C V C
Sbjct: 251 MCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
>M57853-1|AAA60357.1| 676|Homo sapiens S protein protein.
Length = 676
Score = 94.7 bits (225), Expect = 9e-19
Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 16/152 (10%)
Query: 333 CDENA--TCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVG 389
C+E+ +C + +TC C G+QG+ C+ D++EC++ ++G C + C N G
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGG-C--SQICDNTPG 180
Query: 390 GYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GY 446
Y C C G+ +K +C +VDEC C AVC N PG + C C +GY +
Sbjct: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSK 239
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +DEC+E + C + CVN GG+ C C
Sbjct: 240 SCEDIDECSE--NMC--AQLCVNYPGGYTCYC 267
Score = 55.2 bits (127), Expect = 7e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C VD C++ S A C N+ + C+C +G++ + +C+D+DEC E +
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE------N 250
Query: 377 HCHSNTRCVNVVGGYVCQCLG--GY-TRKDKFNCVEVDEC 413
C CVN GGY C C G G+ +D+ +C V C
Sbjct: 251 MCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
>M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein.
Length = 650
Score = 94.7 bits (225), Expect = 9e-19
Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 16/152 (10%)
Query: 333 CDENA--TCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVG 389
C+E+ +C + +TC C G+QG+ C+ D++EC++ ++G C + C N G
Sbjct: 100 CNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGG-C--SQICDNTPG 154
Query: 390 GYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GY 446
Y C C G+ +K +C +VDEC C AVC N PG + C C +GY +
Sbjct: 155 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSK 213
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +DEC+E + C + CVN GG+ C C
Sbjct: 214 SCEDIDECSE--NMC--AQLCVNYPGGYTCYC 241
Score = 55.2 bits (127), Expect = 7e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C VD C++ S A C N+ + C+C +G++ + +C+D+DEC E +
Sbjct: 171 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE------N 224
Query: 377 HCHSNTRCVNVVGGYVCQCLG--GY-TRKDKFNCVEVDEC 413
C CVN GGY C C G G+ +D+ +C V C
Sbjct: 225 MCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 262
>M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin
K-dependent plasma protein S mRNA, complete cds. ).
Length = 676
Score = 94.7 bits (225), Expect = 9e-19
Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 16/152 (10%)
Query: 333 CDENA--TCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVG 389
C+E+ +C + +TC C G+QG+ C+ D++EC++ ++G C + C N G
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGG-C--SQICDNTPG 180
Query: 390 GYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GY 446
Y C C G+ +K +C +VDEC C AVC N PG + C C +GY +
Sbjct: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSK 239
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +DEC+E + C + CVN GG+ C C
Sbjct: 240 SCEDIDECSE--NMC--AQLCVNYPGGYTCYC 267
Score = 55.2 bits (127), Expect = 7e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C VD C++ S A C N+ + C+C +G++ + +C+D+DEC E +
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE------N 250
Query: 377 HCHSNTRCVNVVGGYVCQCLG--GY-TRKDKFNCVEVDEC 413
C CVN GGY C C G G+ +D+ +C V C
Sbjct: 251 MCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
>BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein.
Length = 676
Score = 94.7 bits (225), Expect = 9e-19
Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 16/152 (10%)
Query: 333 CDENA--TCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVG 389
C+E+ +C + +TC C G+QG+ C+ D++EC++ ++G C + C N G
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGG-C--SQICDNTPG 180
Query: 390 GYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GY 446
Y C C G+ +K +C +VDEC C AVC N PG + C C +GY +
Sbjct: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSK 239
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +DEC+E + C + CVN GG+ C C
Sbjct: 240 SCEDIDECSE--NMC--AQLCVNYPGGYTCYC 267
Score = 55.2 bits (127), Expect = 7e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C VD C++ S A C N+ + C+C +G++ + +C+D+DEC E +
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE------N 250
Query: 377 HCHSNTRCVNVVGGYVCQCLG--GY-TRKDKFNCVEVDEC 413
C CVN GGY C C G G+ +D+ +C V C
Sbjct: 251 MCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
>AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein.
Length = 497
Score = 94.7 bits (225), Expect = 9e-19
Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 16/152 (10%)
Query: 333 CDENA--TCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVG 389
C+E+ +C + +TC C G+QG+ C+ D++EC++ ++G C + C N G
Sbjct: 126 CNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGG-C--SQICDNTPG 180
Query: 390 GYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GY 446
Y C C G+ +K +C +VDEC C AVC N PG + C C +GY +
Sbjct: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSK 239
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +DEC+E + C + CVN GG+ C C
Sbjct: 240 SCEDIDECSE--NMC--AQLCVNYPGGYTCYC 267
Score = 55.2 bits (127), Expect = 7e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C VD C++ S A C N+ + C+C +G++ + +C+D+DEC E +
Sbjct: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE------N 250
Query: 377 HCHSNTRCVNVVGGYVCQCLG--GY-TRKDKFNCVEVDEC 413
C CVN GGY C C G G+ +D+ +C V C
Sbjct: 251 MCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin
B12 receptor protein.
Length = 3494
Score = 94.7 bits (225), Expect = 9e-19
Identities = 82/286 (28%), Positives = 117/286 (40%), Gaps = 30/286 (10%)
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDRA-ECKNPVLHPGECCP--TCLRQCLLWGNLYEH 270
G D N C G P+ C C N + CP T QC + Y+
Sbjct: 35 GPLCSADVNECEIYSGT----PLSCQNGGTCVNTMGSYSCHCPPETYGPQC---ASKYDD 87
Query: 271 GERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMG 330
E + C +C D M+ +P+ +C CD S C D C+
Sbjct: 88 CEGGSVARCVHGICED-LMREQAGEPKYSCV---CDAGWMSSPNSPACTL--DRDECSFQ 141
Query: 331 HS-CDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVV 388
C C N + C C G+QG+G C+D++EC+ G G CVN
Sbjct: 142 PGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNG--GCSVAPPVECVNTP 199
Query: 389 GGYVCQ-CLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSY-TCRCRDGYEGDGY 446
G CQ C GY + D C D C + GCH DA C++T GS C C GY G+GY
Sbjct: 200 GSSHCQACPPGY-QGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGY 258
Query: 447 ---TCMHVDE-CTEGSHTCHHSARCVNIDGGFRCECFTENCELSCS 488
C+ + C SH C + +C++ G+ C+C + ++C+
Sbjct: 259 GPNGCVQLSNICL--SHPC-LNGQCIDTVSGYFCKCDSGWTGVNCT 301
Score = 73.3 bits (172), Expect = 2e-12
Identities = 50/165 (30%), Positives = 73/165 (44%), Gaps = 16/165 (9%)
Query: 321 CPGVDYC---NMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLTCQDVDECQEAGGLHGH 376
C ++ C N G S C+N C+ C G+QGDG C D C + G
Sbjct: 174 CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNG---- 229
Query: 377 HCHSNTRCVNVVGGY-VCQCLGGYTRKD--KFNCVEVDECEGNTHGCHADAVCTNTPGSY 433
CH + C + +G +C CL GYT CV++ +H C + C +T Y
Sbjct: 230 GCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNI-CLSHPC-LNGQCIDTVSGY 287
Query: 434 TCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+C G+ G T +++EC S+ C + CV+ F CEC
Sbjct: 288 FCKCDSGWTGVNCT-ENINECL--SNPCLNGGTCVDGVDSFSCEC 329
Score = 58.4 bits (135), Expect = 7e-08
Identities = 43/153 (28%), Positives = 63/153 (41%), Gaps = 13/153 (8%)
Query: 333 CDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYV 392
C C+NL+ + C C ++G L DV+EC+ G C + CVN +G Y
Sbjct: 12 CQNGGNCLNLHDSFFCICPPQWKGP-LCSADVNECEIYSGT-PLSCQNGGTCVNTMGSYS 69
Query: 393 CQCLGGYTRKDKFNCVEVDECEGNT-----HGCHADAVCTNT-PGSYTCRCRDGY--EGD 444
C C T + + D+CEG + HG D + Y+C C G+ +
Sbjct: 70 CHC-PPETYGPQC-ASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMSSPN 127
Query: 445 GYTC-MHVDECTEGSHTCHHSARCVNIDGGFRC 476
C + DEC+ C +C N G F C
Sbjct: 128 SPACTLDRDECSFQPGPCSTLVQCFNTQGSFYC 160
Score = 36.7 bits (81), Expect = 0.26
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 4/82 (4%)
Query: 410 VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHT---CHHSAR 466
VD+ +++ C C N S+ C C ++G V+EC S T C +
Sbjct: 2 VDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGP-LCSADVNECEIYSGTPLSCQNGGT 60
Query: 467 CVNIDGGFRCECFTENCELSCS 488
CVN G + C C E C+
Sbjct: 61 CVNTMGSYSCHCPPETYGPQCA 82
>Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor
protein.
Length = 310
Score = 94.3 bits (224), Expect = 1e-18
Identities = 62/170 (36%), Positives = 85/170 (50%), Gaps = 23/170 (13%)
Query: 320 FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
FC +D C +G H C ++ + K+ C+C+QG+ D TC +D C L+ H
Sbjct: 86 FC-ALDPCVLGTHQC-QHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC----ALNTH 139
Query: 377 HCHSNTRCVNV-VGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSY 433
C CVN G Y C+C GYT +D+ C D+C THGC +C N GS+
Sbjct: 140 GCEHI--CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH--ICVNDRTGSH 195
Query: 434 TCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDG--GFRCECF 479
C C +GY D TC D+C GSH C H CV+ DG + C+C+
Sbjct: 196 HCECYEGYTLNADKKTCSVRDKCALGSHGCQHI--CVS-DGAASYHCDCY 242
Score = 74.5 bits (175), Expect = 1e-12
Identities = 62/198 (31%), Positives = 87/198 (43%), Gaps = 18/198 (9%)
Query: 264 WGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG 323
+G + + RF CA C G QC V + C+ Q +++ + K C
Sbjct: 72 YGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADK-KTCSA 130
Query: 324 VDYCNMG-HSCDENATCMNLNT-KYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCH 379
+D C + H C+ C+N + Y C+C +G+ D TC D+C A G HG C
Sbjct: 131 LDRCALNTHGCEH--ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKC--ALGTHG--CQ 184
Query: 380 SNTRCVN-VVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G + C+C GYT DK C D+C +HGC V ++ SY C C
Sbjct: 185 H--ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICV-SDGAASYHCDC 241
Query: 438 RDGY--EGDGYTCMHVDE 453
GY D TC +E
Sbjct: 242 YPGYTLNEDKKTCSATEE 259
>BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein.
Length = 486
Score = 94.3 bits (224), Expect = 1e-18
Identities = 62/170 (36%), Positives = 85/170 (50%), Gaps = 23/170 (13%)
Query: 320 FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
FC +D C +G H C ++ + K+ C+C+QG+ D TC +D C L+ H
Sbjct: 262 FC-ALDPCVLGTHQC-QHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC----ALNTH 315
Query: 377 HCHSNTRCVNV-VGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSY 433
C CVN G Y C+C GYT +D+ C D+C THGC +C N GS+
Sbjct: 316 GCEHI--CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH--ICVNDRTGSH 371
Query: 434 TCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDG--GFRCECF 479
C C +GY D TC D+C GSH C H CV+ DG + C+C+
Sbjct: 372 HCECYEGYTLNADKKTCSVRDKCALGSHGCQHI--CVS-DGAASYHCDCY 418
Score = 74.5 bits (175), Expect = 1e-12
Identities = 62/198 (31%), Positives = 87/198 (43%), Gaps = 18/198 (9%)
Query: 264 WGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG 323
+G + + RF CA C G QC V + C+ Q +++ + K C
Sbjct: 248 YGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADK-KTCSA 306
Query: 324 VDYCNMG-HSCDENATCMNLNT-KYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCH 379
+D C + H C+ C+N + Y C+C +G+ D TC D+C A G HG C
Sbjct: 307 LDRCALNTHGCEH--ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKC--ALGTHG--CQ 360
Query: 380 SNTRCVN-VVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G + C+C GYT DK C D+C +HGC V ++ SY C C
Sbjct: 361 H--ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICV-SDGAASYHCDC 417
Query: 438 RDGY--EGDGYTCMHVDE 453
GY D TC +E
Sbjct: 418 YPGYTLNEDKKTCSATEE 435
>AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein.
Length = 486
Score = 94.3 bits (224), Expect = 1e-18
Identities = 62/170 (36%), Positives = 85/170 (50%), Gaps = 23/170 (13%)
Query: 320 FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
FC +D C +G H C ++ + K+ C+C+QG+ D TC +D C L+ H
Sbjct: 262 FC-ALDPCVLGTHQC-QHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC----ALNTH 315
Query: 377 HCHSNTRCVNV-VGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSY 433
C CVN G Y C+C GYT +D+ C D+C THGC +C N GS+
Sbjct: 316 GCEHI--CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH--ICVNDRTGSH 371
Query: 434 TCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDG--GFRCECF 479
C C +GY D TC D+C GSH C H CV+ DG + C+C+
Sbjct: 372 HCECYEGYTLNADKKTCSVRDKCALGSHGCQHI--CVS-DGAASYHCDCY 418
Score = 74.5 bits (175), Expect = 1e-12
Identities = 62/198 (31%), Positives = 87/198 (43%), Gaps = 18/198 (9%)
Query: 264 WGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG 323
+G + + RF CA C G QC V + C+ Q +++ + K C
Sbjct: 248 YGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADK-KTCSA 306
Query: 324 VDYCNMG-HSCDENATCMNLNT-KYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCH 379
+D C + H C+ C+N + Y C+C +G+ D TC D+C A G HG C
Sbjct: 307 LDRCALNTHGCEH--ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKC--ALGTHG--CQ 360
Query: 380 SNTRCVN-VVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G + C+C GYT DK C D+C +HGC V ++ SY C C
Sbjct: 361 H--ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICV-SDGAASYHCDC 417
Query: 438 RDGY--EGDGYTCMHVDE 453
GY D TC +E
Sbjct: 418 YPGYTLNEDKKTCSATEE 435
>AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein.
Length = 303
Score = 94.3 bits (224), Expect = 1e-18
Identities = 62/170 (36%), Positives = 85/170 (50%), Gaps = 23/170 (13%)
Query: 320 FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
FC +D C +G H C ++ + K+ C+C+QG+ D TC +D C L+ H
Sbjct: 79 FC-ALDPCVLGTHQC-QHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC----ALNTH 132
Query: 377 HCHSNTRCVNV-VGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSY 433
C CVN G Y C+C GYT +D+ C D+C THGC +C N GS+
Sbjct: 133 GCEHI--CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH--ICVNDRTGSH 188
Query: 434 TCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDG--GFRCECF 479
C C +GY D TC D+C GSH C H CV+ DG + C+C+
Sbjct: 189 HCECYEGYTLNADKKTCSVRDKCALGSHGCQHI--CVS-DGAASYHCDCY 235
Score = 74.5 bits (175), Expect = 1e-12
Identities = 62/198 (31%), Positives = 87/198 (43%), Gaps = 18/198 (9%)
Query: 264 WGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG 323
+G + + RF CA C G QC V + C+ Q +++ + K C
Sbjct: 65 YGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADK-KTCSA 123
Query: 324 VDYCNMG-HSCDENATCMNLNT-KYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCH 379
+D C + H C+ C+N + Y C+C +G+ D TC D+C A G HG C
Sbjct: 124 LDRCALNTHGCEH--ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKC--ALGTHG--CQ 177
Query: 380 SNTRCVN-VVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G + C+C GYT DK C D+C +HGC V ++ SY C C
Sbjct: 178 H--ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICV-SDGAASYHCDC 234
Query: 438 RDGY--EGDGYTCMHVDE 453
GY D TC +E
Sbjct: 235 YPGYTLNEDKKTCSATEE 252
>AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein.
Length = 486
Score = 94.3 bits (224), Expect = 1e-18
Identities = 62/170 (36%), Positives = 85/170 (50%), Gaps = 23/170 (13%)
Query: 320 FCPGVDYCNMG-HSCDENATCMNLNTKYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGH 376
FC +D C +G H C ++ + K+ C+C+QG+ D TC +D C L+ H
Sbjct: 262 FC-ALDPCVLGTHQC-QHVCISDGEGKHHCECSQGYTLNADKKTCSALDRC----ALNTH 315
Query: 377 HCHSNTRCVNV-VGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNT-PGSY 433
C CVN G Y C+C GYT +D+ C D+C THGC +C N GS+
Sbjct: 316 GCEHI--CVNDRSGSYHCECYEGYTLNEDRKTCSAQDKCALGTHGCQH--ICVNDRTGSH 371
Query: 434 TCRCRDGY--EGDGYTCMHVDECTEGSHTCHHSARCVNIDG--GFRCECF 479
C C +GY D TC D+C GSH C H CV+ DG + C+C+
Sbjct: 372 HCECYEGYTLNADKKTCSVRDKCALGSHGCQHI--CVS-DGAASYHCDCY 418
Score = 74.5 bits (175), Expect = 1e-12
Identities = 62/198 (31%), Positives = 87/198 (43%), Gaps = 18/198 (9%)
Query: 264 WGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPG 323
+G + + RF CA C G QC V + C+ Q +++ + K C
Sbjct: 248 YGVIEKLSSRFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADK-KTCSA 306
Query: 324 VDYCNMG-HSCDENATCMNLNT-KYTCKCNQGF--QGDGLTCQDVDECQEAGGLHGHHCH 379
+D C + H C+ C+N + Y C+C +G+ D TC D+C A G HG C
Sbjct: 307 LDRCALNTHGCEH--ICVNDRSGSYHCECYEGYTLNEDRKTCSAQDKC--ALGTHG--CQ 360
Query: 380 SNTRCVN-VVGGYVCQCLGGYT-RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
CVN G + C+C GYT DK C D+C +HGC V ++ SY C C
Sbjct: 361 H--ICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICV-SDGAASYHCDC 417
Query: 438 RDGY--EGDGYTCMHVDE 453
GY D TC +E
Sbjct: 418 YPGYTLNEDKKTCSATEE 435
>BC038587-1|AAH38587.1| 553|Homo sapiens EGF-like-domain, multiple
6 protein.
Length = 553
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/218 (27%), Positives = 96/218 (44%), Gaps = 28/218 (12%)
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
G C TC C + GE P +C C C++ E PC +
Sbjct: 59 GVCEATCEPGC-------KFGECVGPNKC-RCFPGYTGKTCSQDVNECGMKPRPCQH-RC 109
Query: 311 FSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK---------C-NQGFQ--GDG 358
+ G FC +C + TC +N +Y+C+ C + G + +G
Sbjct: 110 VNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Query: 359 LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK---DKFNCVEVDECEG 415
C D+DEC + C N RCVN G Y C+C G+ + +++C++++EC
Sbjct: 170 RDCLDIDECASGKVI----CPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTM 225
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
++H C A C NT GS+ C+C+ GY+G+G C + E
Sbjct: 226 DSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPE 263
Score = 85.4 bits (202), Expect = 6e-16
Identities = 55/174 (31%), Positives = 75/174 (43%), Gaps = 19/174 (10%)
Query: 314 PGECCKFCP-GVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEA 370
PG K C V+ C M C C+N + Y C C G TC + C
Sbjct: 84 PGYTGKTCSQDVNECGMKPRPCQHR--CVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMI 141
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTN 428
+C + C + G C C R + +C+++DEC C + C N
Sbjct: 142 ------NCQYS--CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVN 193
Query: 429 TPGSYTCRCRDGYE----GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T GSY C+C G+E Y C+ ++ECT SHTC H A C N G F+C+C
Sbjct: 194 TFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Score = 40.7 bits (91), Expect = 0.016
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 16/114 (14%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C + VG C+C GYT K +V+EC C C NT GSY C C
Sbjct: 65 CEPGCKFGECVGPNKCRCFPGYTGKTCSQ--DVNECGMKPRPCQHR--CVNTHGSYKCFC 120
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQG 491
G+ M + + T C +S C I+ + CE E + C G
Sbjct: 121 LSGH-------MLMPDAT-----CVNSRTCAMINCQYSCEDTEEGPQCLCPSSG 162
>AY358333-1|AAQ88699.1| 338|Homo sapiens EGFL6 protein.
Length = 338
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/218 (27%), Positives = 96/218 (44%), Gaps = 28/218 (12%)
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
G C TC C + GE P +C C C++ E PC +
Sbjct: 59 GVCEATCEPGC-------KFGECVGPNKC-RCFPGYTGKTCSQDVNECGMKPRPCQH-RC 109
Query: 311 FSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK---------C-NQGFQ--GDG 358
+ G FC +C + TC +N +Y+C+ C + G + +G
Sbjct: 110 VNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Query: 359 LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK---DKFNCVEVDECEG 415
C D+DEC + C N RCVN G Y C+C G+ + +++C++++EC
Sbjct: 170 RDCLDIDECASGKVI----CPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTM 225
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
++H C A C NT GS+ C+C+ GY+G+G C + E
Sbjct: 226 DSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPE 263
Score = 85.4 bits (202), Expect = 6e-16
Identities = 55/174 (31%), Positives = 75/174 (43%), Gaps = 19/174 (10%)
Query: 314 PGECCKFCP-GVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEA 370
PG K C V+ C M C C+N + Y C C G TC + C
Sbjct: 84 PGYTGKTCSQDVNECGMKPRPCQHR--CVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMI 141
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTN 428
+C + C + G C C R + +C+++DEC C + C N
Sbjct: 142 ------NCQYS--CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVN 193
Query: 429 TPGSYTCRCRDGYE----GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T GSY C+C G+E Y C+ ++ECT SHTC H A C N G F+C+C
Sbjct: 194 TFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Score = 40.7 bits (91), Expect = 0.016
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 16/114 (14%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C + VG C+C GYT K +V+EC C C NT GSY C C
Sbjct: 65 CEPGCKFGECVGPNKCRCFPGYTGKTCSQ--DVNECGMKPRPCQHR--CVNTHGSYKCFC 120
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQG 491
G+ M + + T C +S C I+ + CE E + C G
Sbjct: 121 LSGH-------MLMPDAT-----CVNSRTCAMINCQYSCEDTEEGPQCLCPSSG 162
>AK075214-1|BAC11477.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ90733 fis, clone PLACE1010251, highly similar to
Epidermal growth factor-like protein 6 precursor. ).
Length = 553
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/218 (27%), Positives = 96/218 (44%), Gaps = 28/218 (12%)
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
G C TC C + GE P +C C C++ E PC +
Sbjct: 59 GVCEATCEPGC-------KFGECVGPNKC-RCFPGYTGKTCSQDVNECGMKPRPCQH-RC 109
Query: 311 FSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK---------C-NQGFQ--GDG 358
+ G FC +C + TC +N +Y+C+ C + G + +G
Sbjct: 110 VNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Query: 359 LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK---DKFNCVEVDECEG 415
C D+DEC + C N RCVN G Y C+C G+ + +++C++++EC
Sbjct: 170 RDCLDIDECASGKVI----CPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTM 225
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
++H C A C NT GS+ C+C+ GY+G+G C + E
Sbjct: 226 DSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPE 263
Score = 85.4 bits (202), Expect = 6e-16
Identities = 55/174 (31%), Positives = 75/174 (43%), Gaps = 19/174 (10%)
Query: 314 PGECCKFCP-GVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEA 370
PG K C V+ C M C C+N + Y C C G TC + C
Sbjct: 84 PGYTGKTCSQDVNECGMKPRPCQHR--CVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMI 141
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTN 428
+C + C + G C C R + +C+++DEC C + C N
Sbjct: 142 ------NCQYS--CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVN 193
Query: 429 TPGSYTCRCRDGYE----GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T GSY C+C G+E Y C+ ++ECT SHTC H A C N G F+C+C
Sbjct: 194 TFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Score = 40.7 bits (91), Expect = 0.016
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 16/114 (14%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C + VG C+C GYT K +V+EC C C NT GSY C C
Sbjct: 65 CEPGCKFGECVGPNKCRCFPGYTGKTCSQ--DVNECGMKPRPCQHR--CVNTHGSYKCFC 120
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQG 491
G+ M + + T C +S C I+ + CE E + C G
Sbjct: 121 LSGH-------MLMPDAT-----CVNSRTCAMINCQYSCEDTEEGPQCLCPSSG 162
>AJ245671-1|CAB92132.1| 554|Homo sapiens hypothetical protein
protein.
Length = 554
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/218 (27%), Positives = 96/218 (44%), Gaps = 28/218 (12%)
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
G C TC C + GE P +C C C++ E PC +
Sbjct: 59 GVCEATCEPGC-------KFGECVGPNKC-RCFPGYTGKTCSQDVNECGMKPRPCQH-RC 109
Query: 311 FSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK---------C-NQGFQ--GDG 358
+ G FC +C + TC +N +Y+C+ C + G + +G
Sbjct: 110 VNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Query: 359 LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK---DKFNCVEVDECEG 415
C D+DEC + C N RCVN G Y C+C G+ + +++C++++EC
Sbjct: 170 RDCLDIDECASGKVI----CPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTM 225
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
++H C A C NT GS+ C+C+ GY+G+G C + E
Sbjct: 226 DSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPE 263
Score = 85.4 bits (202), Expect = 6e-16
Identities = 55/174 (31%), Positives = 75/174 (43%), Gaps = 19/174 (10%)
Query: 314 PGECCKFCP-GVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEA 370
PG K C V+ C M C C+N + Y C C G TC + C
Sbjct: 84 PGYTGKTCSQDVNECGMKPRPCQHR--CVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMI 141
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTN 428
+C + C + G C C R + +C+++DEC C + C N
Sbjct: 142 ------NCQYS--CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVN 193
Query: 429 TPGSYTCRCRDGYE----GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T GSY C+C G+E Y C+ ++ECT SHTC H A C N G F+C+C
Sbjct: 194 TFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Score = 40.7 bits (91), Expect = 0.016
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 16/114 (14%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C + VG C+C GYT K +V+EC C C NT GSY C C
Sbjct: 65 CEPGCKFGECVGPNKCRCFPGYTGKTCSQ--DVNECGMKPRPCQHR--CVNTHGSYKCFC 120
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQG 491
G+ M + + T C +S C I+ + CE E + C G
Sbjct: 121 LSGH-------MLMPDAT-----CVNSRTCAMINCQYSCEDTEEGPQCLCPSSG 162
>AF186084-1|AAF27812.1| 553|Homo sapiens epidermal growth factor
repeat containing protein protein.
Length = 553
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/218 (27%), Positives = 96/218 (44%), Gaps = 28/218 (12%)
Query: 251 GECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ 310
G C TC C + GE P +C C C++ E PC +
Sbjct: 59 GVCEATCEPGC-------KFGECVGPNKC-RCFPGYTGKTCSQDVNECGMKPRPCQH-RC 109
Query: 311 FSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCK---------C-NQGFQ--GDG 358
+ G FC +C + TC +N +Y+C+ C + G + +G
Sbjct: 110 VNTHGSYKCFCLSGHMLMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNG 169
Query: 359 LTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK---DKFNCVEVDECEG 415
C D+DEC + C N RCVN G Y C+C G+ + +++C++++EC
Sbjct: 170 RDCLDIDECASGKVI----CPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTM 225
Query: 416 NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
++H C A C NT GS+ C+C+ GY+G+G C + E
Sbjct: 226 DSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCSAIPE 263
Score = 85.4 bits (202), Expect = 6e-16
Identities = 55/174 (31%), Positives = 75/174 (43%), Gaps = 19/174 (10%)
Query: 314 PGECCKFCP-GVDYCNMG-HSCDENATCMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEA 370
PG K C V+ C M C C+N + Y C C G TC + C
Sbjct: 84 PGYTGKTCSQDVNECGMKPRPCQHR--CVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMI 141
Query: 371 GGLHGHHCHSNTRCVNVVGGYVCQCLGGYTR--KDKFNCVEVDECEGNTHGCHADAVCTN 428
+C + C + G C C R + +C+++DEC C + C N
Sbjct: 142 ------NCQYS--CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVN 193
Query: 429 TPGSYTCRCRDGYE----GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
T GSY C+C G+E Y C+ ++ECT SHTC H A C N G F+C+C
Sbjct: 194 TFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKC 247
Score = 40.7 bits (91), Expect = 0.016
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 16/114 (14%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRC 437
C + VG C+C GYT K +V+EC C C NT GSY C C
Sbjct: 65 CEPGCKFGECVGPNKCRCFPGYTGKTCSQ--DVNECGMKPRPCQHR--CVNTHGSYKCFC 120
Query: 438 RDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQG 491
G+ M + + T C +S C I+ + CE E + C G
Sbjct: 121 LSGH-------MLMPDAT-----CVNSRTCAMINCQYSCEDTEEGPQCLCPSSG 162
>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
precursor protein.
Length = 1285
Score = 91.9 bits (218), Expect = 6e-18
Identities = 69/207 (33%), Positives = 93/207 (44%), Gaps = 27/207 (13%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P+ CA CH G + C P+ R C P Q G C+ +D C C
Sbjct: 68 PRGCATQPCHHGAL-CVPQGPDPTGFRCYCVPGFQ----GPRCEL--DIDEC-ASRPCHH 119
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
ATC NL +Y C C G+ G+TC+ +VDEC A LHG C++ VG + C
Sbjct: 120 GATCRNLADRYECHCPLGYA--GVTCEMEVDECASAPCLHG------GSCLDGVGSFRCV 171
Query: 395 CLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCR-DGYEGDGYTCMHVD 452
C GY C +++DEC+ + C C + + C C GYEG + V
Sbjct: 172 CAPGY---GGTRCQLDLDECQ--SQPCAHGGTCHDLVNGFRCDCAGTGYEGT-HCEREVL 225
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCECF 479
EC S C H+A C+ G FRC C+
Sbjct: 226 EC--ASAPCEHNASCLEGLGSFRCLCW 250
Score = 79.4 bits (187), Expect = 4e-14
Identities = 86/290 (29%), Positives = 110/290 (37%), Gaps = 47/290 (16%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKEC 279
+C C HG TCR + DR EC P+ + G C + +C L+ G
Sbjct: 111 ECASRPCHHGA-TCRNL-ADRYECHCPLGYAGVTCEMEVDECASAPCLHG-GSCLDGVGS 167
Query: 280 AECVCHDGNMQCTRVDPEL-ACPRLPCDPPQQFS--VPGECCKFCPGVDY----CNM--- 329
CVC G TR +L C PC V G C C G Y C
Sbjct: 168 FRCVCAPG-YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD-CAGTGYEGTHCEREVL 225
Query: 330 ---GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHC--HSNTR 383
C+ NA+C+ + C C G+ G+ C+ D DEC + HG C S+
Sbjct: 226 ECASAPCEHNASCLEGLGSFRCLCWPGYSGE--LCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 384 CVNVV-------------GGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNT 429
V G++C C G+ D C VEVDEC C C +
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGAD---CGVEVDECASRP--CLNGGHCQDL 338
Query: 430 PGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCEC 478
P + C C DGY G TC VDEC S C H C + G+ C C
Sbjct: 339 PNGFQCHCPDGYAGP--TCEEDVDECL--SDPCLHGGTCSDTVAGYICRC 384
Score = 70.5 bits (165), Expect = 2e-11
Identities = 75/264 (28%), Positives = 100/264 (37%), Gaps = 31/264 (11%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECC 254
L++C Q C GT H ++ DC +EC A C+ H C
Sbjct: 185 LDECQSQP-CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE----HNASCL 239
Query: 255 PTCLR-QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS- 312
+CL W ECA C G R DP L + P FS
Sbjct: 240 EGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPAL-YGGVQAAFPGAFSF 298
Query: 313 --VPGECCKFCPGVDYCNMGHSCDENAT--------CMNLNTKYTCKCNQGFQGDGLTC- 361
G C PG + + G DE A+ C +L + C C G+ G TC
Sbjct: 299 RHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGP--TCE 356
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH 421
+DVDEC LHG C S+T V GY+C+C + +D V++ C+G+T
Sbjct: 357 EDVDECLSDPCLHGGTC-SDT-----VAGYICRCPETWGGRD--CSVQLTGCQGHTCPLA 408
Query: 422 ADAVCTNTPG--SYTCRCRDGYEG 443
A + G SY C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 64.5 bits (150), Expect = 1e-09
Identities = 45/132 (34%), Positives = 55/132 (41%), Gaps = 18/132 (13%)
Query: 352 QGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV---VGGYVCQCLGGYTRKDKFNC- 407
Q + G TC + E G CH CV G+ C C+ G+ C
Sbjct: 54 QATESGGYTCGPM----EPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP---RCE 106
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSAR 466
+++DEC CH A C N Y C C GY G TC M VDEC S C H
Sbjct: 107 LDIDECASRP--CHHGATCRNLADRYECHCPLGYA--GVTCEMEVDEC--ASAPCLHGGS 160
Query: 467 CVNIDGGFRCEC 478
C++ G FRC C
Sbjct: 161 CLDGVGSFRCVC 172
Score = 58.4 bits (135), Expect = 7e-08
Identities = 74/265 (27%), Positives = 100/265 (37%), Gaps = 36/265 (13%)
Query: 223 RCSCVHGEITCRPVECDRAECKN-PVLHPGECCPTCLR-QCLLWGNLYE--HGERFAPKE 278
RC C G R + D EC++ P H G C +C G YE H ER E
Sbjct: 169 RCVCAPGYGGTR-CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREV-LE 226
Query: 279 CAECVCHDGNMQCTRVDPELACPRLP------C--DPPQQFSVP----GECCKFCPGVDY 326
CA C + N C C P C D + S P G C + Y
Sbjct: 227 CASAPC-EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + A + C C GF+G + VDEC L+G HC +
Sbjct: 286 GGV-QAAFPGAFSFRHAAGFLCHCPPGFEGADCGVE-VDECASRPCLNGGHCQ------D 337
Query: 387 VVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+ G+ C C GY C E VDEC + C C++T Y CRC + + G
Sbjct: 338 LPNGFQCHCPDGYAGP---TCEEDVDECLSDP--CLHGGTCSDTVAGYICRCPETWGGRD 392
Query: 446 YTCMHVDECTEGSHTCHHSARCVNI 470
+ + + C HTC +A C+ I
Sbjct: 393 CS-VQLTGCQ--GHTCPLAATCIPI 414
Score = 47.2 bits (107), Expect = 2e-04
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNT---PGSYTCRCRDGYEGDGYTCMHVDECTE 456
T + C ++ T CH A+C P + C C G++G + +DEC
Sbjct: 56 TESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCE-LDIDECA- 113
Query: 457 GSHTCHHSARCVNIDGGFRCECFTENCELSCSWQ 490
S CHH A C N+ + C C ++C +
Sbjct: 114 -SRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
Score = 35.1 bits (77), Expect = 0.79
Identities = 19/59 (32%), Positives = 24/59 (40%), Gaps = 3/59 (5%)
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C D C + ++ C C G+EG HVD C S C + DG F C C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEA-HVDPC--HSAPCARGRCHTHPDGRFECRC 1120
>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 91.9 bits (218), Expect = 6e-18
Identities = 69/207 (33%), Positives = 93/207 (44%), Gaps = 27/207 (13%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P+ CA CH G + C P+ R C P Q G C+ +D C C
Sbjct: 68 PRGCATQPCHHGAL-CVPQGPDPTGFRCYCVPGFQ----GPRCEL--DIDEC-ASRPCHH 119
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
ATC NL +Y C C G+ G+TC+ +VDEC A LHG C++ VG + C
Sbjct: 120 GATCRNLADRYECHCPLGYA--GVTCEMEVDECASAPCLHG------GSCLDGVGSFRCV 171
Query: 395 CLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCR-DGYEGDGYTCMHVD 452
C GY C +++DEC+ + C C + + C C GYEG + V
Sbjct: 172 CAPGY---GGTRCQLDLDECQ--SQPCAHGGTCHDLVNGFRCDCAGTGYEGT-HCEREVL 225
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCECF 479
EC S C H+A C+ G FRC C+
Sbjct: 226 EC--ASAPCEHNASCLEGLGSFRCLCW 250
Score = 79.4 bits (187), Expect = 4e-14
Identities = 86/290 (29%), Positives = 110/290 (37%), Gaps = 47/290 (16%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKEC 279
+C C HG TCR + DR EC P+ + G C + +C L+ G
Sbjct: 111 ECASRPCHHGA-TCRNL-ADRYECHCPLGYAGVTCEMEVDECASAPCLHG-GSCLDGVGS 167
Query: 280 AECVCHDGNMQCTRVDPEL-ACPRLPCDPPQQFS--VPGECCKFCPGVDY----CNM--- 329
CVC G TR +L C PC V G C C G Y C
Sbjct: 168 FRCVCAPG-YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD-CAGTGYEGTHCEREVL 225
Query: 330 ---GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHC--HSNTR 383
C+ NA+C+ + C C G+ G+ C+ D DEC + HG C S+
Sbjct: 226 ECASAPCEHNASCLEGLGSFRCLCWPGYSGE--LCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 384 CVNVV-------------GGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNT 429
V G++C C G+ D C VEVDEC C C +
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGAD---CGVEVDECASRP--CLNGGHCQDL 338
Query: 430 PGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCEC 478
P + C C DGY G TC VDEC S C H C + G+ C C
Sbjct: 339 PNGFQCHCPDGYAGP--TCEEDVDECL--SDPCLHGGTCSDTVAGYICRC 384
Score = 70.5 bits (165), Expect = 2e-11
Identities = 75/264 (28%), Positives = 100/264 (37%), Gaps = 31/264 (11%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECC 254
L++C Q C GT H ++ DC +EC A C+ H C
Sbjct: 185 LDECQSQP-CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE----HNASCL 239
Query: 255 PTCLR-QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS- 312
+CL W ECA C G R DP L + P FS
Sbjct: 240 EGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPAL-YGGVQAAFPGAFSF 298
Query: 313 --VPGECCKFCPGVDYCNMGHSCDENAT--------CMNLNTKYTCKCNQGFQGDGLTC- 361
G C PG + + G DE A+ C +L + C C G+ G TC
Sbjct: 299 RHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGP--TCE 356
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH 421
+DVDEC LHG C S+T V GY+C+C + +D V++ C+G+T
Sbjct: 357 EDVDECLSDPCLHGGTC-SDT-----VAGYICRCPETWGGRD--CSVQLTGCQGHTCPLA 408
Query: 422 ADAVCTNTPG--SYTCRCRDGYEG 443
A + G SY C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 64.5 bits (150), Expect = 1e-09
Identities = 45/132 (34%), Positives = 55/132 (41%), Gaps = 18/132 (13%)
Query: 352 QGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV---VGGYVCQCLGGYTRKDKFNC- 407
Q + G TC + E G CH CV G+ C C+ G+ C
Sbjct: 54 QATESGGYTCGPM----EPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP---RCE 106
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSAR 466
+++DEC CH A C N Y C C GY G TC M VDEC S C H
Sbjct: 107 LDIDECASRP--CHHGATCRNLADRYECHCPLGYA--GVTCEMEVDEC--ASAPCLHGGS 160
Query: 467 CVNIDGGFRCEC 478
C++ G FRC C
Sbjct: 161 CLDGVGSFRCVC 172
Score = 58.4 bits (135), Expect = 7e-08
Identities = 74/265 (27%), Positives = 100/265 (37%), Gaps = 36/265 (13%)
Query: 223 RCSCVHGEITCRPVECDRAECKN-PVLHPGECCPTCLR-QCLLWGNLYE--HGERFAPKE 278
RC C G R + D EC++ P H G C +C G YE H ER E
Sbjct: 169 RCVCAPGYGGTR-CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREV-LE 226
Query: 279 CAECVCHDGNMQCTRVDPELACPRLP------C--DPPQQFSVP----GECCKFCPGVDY 326
CA C + N C C P C D + S P G C + Y
Sbjct: 227 CASAPC-EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + A + C C GF+G + VDEC L+G HC +
Sbjct: 286 GGV-QAAFPGAFSFRHAAGFLCHCPPGFEGADCGVE-VDECASRPCLNGGHCQ------D 337
Query: 387 VVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+ G+ C C GY C E VDEC + C C++T Y CRC + + G
Sbjct: 338 LPNGFQCHCPDGYAGP---TCEEDVDECLSDP--CLHGGTCSDTVAGYICRCPETWGGRD 392
Query: 446 YTCMHVDECTEGSHTCHHSARCVNI 470
+ + + C HTC +A C+ I
Sbjct: 393 CS-VQLTGCQ--GHTCPLAATCIPI 414
Score = 47.2 bits (107), Expect = 2e-04
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNT---PGSYTCRCRDGYEGDGYTCMHVDECTE 456
T + C ++ T CH A+C P + C C G++G + +DEC
Sbjct: 56 TESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCE-LDIDECA- 113
Query: 457 GSHTCHHSARCVNIDGGFRCECFTENCELSCSWQ 490
S CHH A C N+ + C C ++C +
Sbjct: 114 -SRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
Score = 35.1 bits (77), Expect = 0.79
Identities = 19/59 (32%), Positives = 24/59 (40%), Gaps = 3/59 (5%)
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C D C + ++ C C G+EG HVD C S C + DG F C C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEA-HVDPC--HSAPCARGRCHTHPDGRFECRC 1120
>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 91.9 bits (218), Expect = 6e-18
Identities = 69/207 (33%), Positives = 93/207 (44%), Gaps = 27/207 (13%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P+ CA CH G + C P+ R C P Q G C+ +D C C
Sbjct: 68 PRGCATQPCHHGAL-CVPQGPDPTGFRCYCVPGFQ----GPRCEL--DIDEC-ASRPCHH 119
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
ATC NL +Y C C G+ G+TC+ +VDEC A LHG C++ VG + C
Sbjct: 120 GATCRNLADRYECHCPLGYA--GVTCEMEVDECASAPCLHG------GSCLDGVGSFRCV 171
Query: 395 CLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCR-DGYEGDGYTCMHVD 452
C GY C +++DEC+ + C C + + C C GYEG + V
Sbjct: 172 CAPGY---GGTRCQLDLDECQ--SQPCAHGGTCHDLVNGFRCDCAGTGYEGT-HCEREVL 225
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCECF 479
EC S C H+A C+ G FRC C+
Sbjct: 226 EC--ASAPCEHNASCLEGLGSFRCLCW 250
Score = 79.4 bits (187), Expect = 4e-14
Identities = 86/290 (29%), Positives = 110/290 (37%), Gaps = 47/290 (16%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKEC 279
+C C HG TCR + DR EC P+ + G C + +C L+ G
Sbjct: 111 ECASRPCHHGA-TCRNL-ADRYECHCPLGYAGVTCEMEVDECASAPCLHG-GSCLDGVGS 167
Query: 280 AECVCHDGNMQCTRVDPEL-ACPRLPCDPPQQFS--VPGECCKFCPGVDY----CNM--- 329
CVC G TR +L C PC V G C C G Y C
Sbjct: 168 FRCVCAPG-YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD-CAGTGYEGTHCEREVL 225
Query: 330 ---GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHC--HSNTR 383
C+ NA+C+ + C C G+ G+ C+ D DEC + HG C S+
Sbjct: 226 ECASAPCEHNASCLEGLGSFRCLCWPGYSGE--LCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 384 CVNVV-------------GGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNT 429
V G++C C G+ D C VEVDEC C C +
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGAD---CGVEVDECASRP--CLNGGHCQDL 338
Query: 430 PGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCEC 478
P + C C DGY G TC VDEC S C H C + G+ C C
Sbjct: 339 PNGFQCHCPDGYAGP--TCEEDVDECL--SDPCLHGGTCSDTVAGYICRC 384
Score = 70.5 bits (165), Expect = 2e-11
Identities = 75/264 (28%), Positives = 100/264 (37%), Gaps = 31/264 (11%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECC 254
L++C Q C GT H ++ DC +EC A C+ H C
Sbjct: 185 LDECQSQP-CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE----HNASCL 239
Query: 255 PTCLR-QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS- 312
+CL W ECA C G R DP L + P FS
Sbjct: 240 EGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPAL-YGGVQAAFPGAFSF 298
Query: 313 --VPGECCKFCPGVDYCNMGHSCDENAT--------CMNLNTKYTCKCNQGFQGDGLTC- 361
G C PG + + G DE A+ C +L + C C G+ G TC
Sbjct: 299 RHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGP--TCE 356
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH 421
+DVDEC LHG C S+T V GY+C+C + +D V++ C+G+T
Sbjct: 357 EDVDECLSDPCLHGGTC-SDT-----VAGYICRCPETWGGRD--CSVQLTGCQGHTCPLA 408
Query: 422 ADAVCTNTPG--SYTCRCRDGYEG 443
A + G SY C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 64.5 bits (150), Expect = 1e-09
Identities = 45/132 (34%), Positives = 55/132 (41%), Gaps = 18/132 (13%)
Query: 352 QGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV---VGGYVCQCLGGYTRKDKFNC- 407
Q + G TC + E G CH CV G+ C C+ G+ C
Sbjct: 54 QATESGGYTCGPM----EPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP---RCE 106
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSAR 466
+++DEC CH A C N Y C C GY G TC M VDEC S C H
Sbjct: 107 LDIDECASRP--CHHGATCRNLADRYECHCPLGYA--GVTCEMEVDEC--ASAPCLHGGS 160
Query: 467 CVNIDGGFRCEC 478
C++ G FRC C
Sbjct: 161 CLDGVGSFRCVC 172
Score = 58.4 bits (135), Expect = 7e-08
Identities = 74/265 (27%), Positives = 100/265 (37%), Gaps = 36/265 (13%)
Query: 223 RCSCVHGEITCRPVECDRAECKN-PVLHPGECCPTCLR-QCLLWGNLYE--HGERFAPKE 278
RC C G R + D EC++ P H G C +C G YE H ER E
Sbjct: 169 RCVCAPGYGGTR-CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREV-LE 226
Query: 279 CAECVCHDGNMQCTRVDPELACPRLP------C--DPPQQFSVP----GECCKFCPGVDY 326
CA C + N C C P C D + S P G C + Y
Sbjct: 227 CASAPC-EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + A + C C GF+G + VDEC L+G HC +
Sbjct: 286 GGV-QAAFPGAFSFRHAAGFLCHCPPGFEGADCGVE-VDECASRPCLNGGHCQ------D 337
Query: 387 VVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+ G+ C C GY C E VDEC + C C++T Y CRC + + G
Sbjct: 338 LPNGFQCHCPDGYAGP---TCEEDVDECLSDP--CLHGGTCSDTVAGYICRCPETWGGRD 392
Query: 446 YTCMHVDECTEGSHTCHHSARCVNI 470
+ + + C HTC +A C+ I
Sbjct: 393 CS-VQLTGCQ--GHTCPLAATCIPI 414
Score = 47.2 bits (107), Expect = 2e-04
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNT---PGSYTCRCRDGYEGDGYTCMHVDECTE 456
T + C ++ T CH A+C P + C C G++G + +DEC
Sbjct: 56 TESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCE-LDIDECA- 113
Query: 457 GSHTCHHSARCVNIDGGFRCECFTENCELSCSWQ 490
S CHH A C N+ + C C ++C +
Sbjct: 114 -SRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
Score = 37.5 bits (83), Expect = 0.15
Identities = 22/72 (30%), Positives = 27/72 (37%), Gaps = 3/72 (4%)
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C D C + ++ C C G+EG HVD C S C + DG F C C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEA-HVDPC--HSAPCARGRCHTHPDGRFECRCP 1121
Query: 480 TENCELSCSWQG 491
C W G
Sbjct: 1122 PGFGGPRCRWDG 1133
>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 91.9 bits (218), Expect = 6e-18
Identities = 69/207 (33%), Positives = 93/207 (44%), Gaps = 27/207 (13%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P+ CA CH G + C P+ R C P Q G C+ +D C C
Sbjct: 68 PRGCATQPCHHGAL-CVPQGPDPTGFRCYCVPGFQ----GPRCEL--DIDEC-ASRPCHH 119
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
ATC NL +Y C C G+ G+TC+ +VDEC A LHG C++ VG + C
Sbjct: 120 GATCRNLADRYECHCPLGYA--GVTCEMEVDECASAPCLHG------GSCLDGVGSFRCV 171
Query: 395 CLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCR-DGYEGDGYTCMHVD 452
C GY C +++DEC+ + C C + + C C GYEG + V
Sbjct: 172 CAPGY---GGTRCQLDLDECQ--SQPCAHGGTCHDLVNGFRCDCAGTGYEGT-HCEREVL 225
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCECF 479
EC S C H+A C+ G FRC C+
Sbjct: 226 EC--ASAPCEHNASCLEGLGSFRCLCW 250
Score = 79.4 bits (187), Expect = 4e-14
Identities = 86/290 (29%), Positives = 110/290 (37%), Gaps = 47/290 (16%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKEC 279
+C C HG TCR + DR EC P+ + G C + +C L+ G
Sbjct: 111 ECASRPCHHGA-TCRNL-ADRYECHCPLGYAGVTCEMEVDECASAPCLHG-GSCLDGVGS 167
Query: 280 AECVCHDGNMQCTRVDPEL-ACPRLPCDPPQQFS--VPGECCKFCPGVDY----CNM--- 329
CVC G TR +L C PC V G C C G Y C
Sbjct: 168 FRCVCAPG-YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD-CAGTGYEGTHCEREVL 225
Query: 330 ---GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHC--HSNTR 383
C+ NA+C+ + C C G+ G+ C+ D DEC + HG C S+
Sbjct: 226 ECASAPCEHNASCLEGLGSFRCLCWPGYSGE--LCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 384 CVNVV-------------GGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNT 429
V G++C C G+ D C VEVDEC C C +
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGAD---CGVEVDECASRP--CLNGGHCQDL 338
Query: 430 PGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCEC 478
P + C C DGY G TC VDEC S C H C + G+ C C
Sbjct: 339 PNGFQCHCPDGYAGP--TCEEDVDECL--SDPCLHGGTCSDTVAGYICRC 384
Score = 70.5 bits (165), Expect = 2e-11
Identities = 75/264 (28%), Positives = 100/264 (37%), Gaps = 31/264 (11%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECC 254
L++C Q C GT H ++ DC +EC A C+ H C
Sbjct: 185 LDECQSQP-CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE----HNASCL 239
Query: 255 PTCLR-QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS- 312
+CL W ECA C G R DP L + P FS
Sbjct: 240 EGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPAL-YGGVQAAFPGAFSF 298
Query: 313 --VPGECCKFCPGVDYCNMGHSCDENAT--------CMNLNTKYTCKCNQGFQGDGLTC- 361
G C PG + + G DE A+ C +L + C C G+ G TC
Sbjct: 299 RHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGP--TCE 356
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH 421
+DVDEC LHG C S+T V GY+C+C + +D V++ C+G+T
Sbjct: 357 EDVDECLSDPCLHGGTC-SDT-----VAGYICRCPETWGGRD--CSVQLTGCQGHTCPLA 408
Query: 422 ADAVCTNTPG--SYTCRCRDGYEG 443
A + G SY C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 64.5 bits (150), Expect = 1e-09
Identities = 45/132 (34%), Positives = 55/132 (41%), Gaps = 18/132 (13%)
Query: 352 QGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV---VGGYVCQCLGGYTRKDKFNC- 407
Q + G TC + E G CH CV G+ C C+ G+ C
Sbjct: 54 QATESGGYTCGPM----EPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP---RCE 106
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSAR 466
+++DEC CH A C N Y C C GY G TC M VDEC S C H
Sbjct: 107 LDIDECASRP--CHHGATCRNLADRYECHCPLGYA--GVTCEMEVDEC--ASAPCLHGGS 160
Query: 467 CVNIDGGFRCEC 478
C++ G FRC C
Sbjct: 161 CLDGVGSFRCVC 172
Score = 58.4 bits (135), Expect = 7e-08
Identities = 74/265 (27%), Positives = 100/265 (37%), Gaps = 36/265 (13%)
Query: 223 RCSCVHGEITCRPVECDRAECKN-PVLHPGECCPTCLR-QCLLWGNLYE--HGERFAPKE 278
RC C G R + D EC++ P H G C +C G YE H ER E
Sbjct: 169 RCVCAPGYGGTR-CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREV-LE 226
Query: 279 CAECVCHDGNMQCTRVDPELACPRLP------C--DPPQQFSVP----GECCKFCPGVDY 326
CA C + N C C P C D + S P G C + Y
Sbjct: 227 CASAPC-EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + A + C C GF+G + VDEC L+G HC +
Sbjct: 286 GGV-QAAFPGAFSFRHAAGFLCHCPPGFEGADCGVE-VDECASRPCLNGGHCQ------D 337
Query: 387 VVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+ G+ C C GY C E VDEC + C C++T Y CRC + + G
Sbjct: 338 LPNGFQCHCPDGYAGP---TCEEDVDECLSDP--CLHGGTCSDTVAGYICRCPETWGGRD 392
Query: 446 YTCMHVDECTEGSHTCHHSARCVNI 470
+ + + C HTC +A C+ I
Sbjct: 393 CS-VQLTGCQ--GHTCPLAATCIPI 414
Score = 47.2 bits (107), Expect = 2e-04
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNT---PGSYTCRCRDGYEGDGYTCMHVDECTE 456
T + C ++ T CH A+C P + C C G++G + +DEC
Sbjct: 56 TESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCE-LDIDECA- 113
Query: 457 GSHTCHHSARCVNIDGGFRCECFTENCELSCSWQ 490
S CHH A C N+ + C C ++C +
Sbjct: 114 -SRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
Score = 35.1 bits (77), Expect = 0.79
Identities = 19/59 (32%), Positives = 24/59 (40%), Gaps = 3/59 (5%)
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C D C + ++ C C G+EG HVD C S C + DG F C C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEA-HVDPC--HSAPCARGRCHTHPDGRFECRC 1120
>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 91.9 bits (218), Expect = 6e-18
Identities = 69/207 (33%), Positives = 93/207 (44%), Gaps = 27/207 (13%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P+ CA CH G + C P+ R C P Q G C+ +D C C
Sbjct: 68 PRGCATQPCHHGAL-CVPQGPDPTGFRCYCVPGFQ----GPRCEL--DIDEC-ASRPCHH 119
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
ATC NL +Y C C G+ G+TC+ +VDEC A LHG C++ VG + C
Sbjct: 120 GATCRNLADRYECHCPLGYA--GVTCEMEVDECASAPCLHG------GSCLDGVGSFRCV 171
Query: 395 CLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCR-DGYEGDGYTCMHVD 452
C GY C +++DEC+ + C C + + C C GYEG + V
Sbjct: 172 CAPGY---GGTRCQLDLDECQ--SQPCAHGGTCHDLVNGFRCDCAGTGYEGT-HCEREVL 225
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCECF 479
EC S C H+A C+ G FRC C+
Sbjct: 226 EC--ASAPCEHNASCLEGLGSFRCLCW 250
Score = 79.4 bits (187), Expect = 4e-14
Identities = 86/290 (29%), Positives = 110/290 (37%), Gaps = 47/290 (16%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKEC 279
+C C HG TCR + DR EC P+ + G C + +C L+ G
Sbjct: 111 ECASRPCHHGA-TCRNL-ADRYECHCPLGYAGVTCEMEVDECASAPCLHG-GSCLDGVGS 167
Query: 280 AECVCHDGNMQCTRVDPEL-ACPRLPCDPPQQFS--VPGECCKFCPGVDY----CNM--- 329
CVC G TR +L C PC V G C C G Y C
Sbjct: 168 FRCVCAPG-YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD-CAGTGYEGTHCEREVL 225
Query: 330 ---GHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHC--HSNTR 383
C+ NA+C+ + C C G+ G+ C+ D DEC + HG C S+
Sbjct: 226 ECASAPCEHNASCLEGLGSFRCLCWPGYSGE--LCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 384 CVNVV-------------GGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNT 429
V G++C C G+ D C VEVDEC C C +
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGAD---CGVEVDECASRP--CLNGGHCQDL 338
Query: 430 PGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCEC 478
P + C C DGY G TC VDEC S C H C + G+ C C
Sbjct: 339 PNGFQCHCPDGYAGP--TCEEDVDECL--SDPCLHGGTCSDTVAGYICRC 384
Score = 70.5 bits (165), Expect = 2e-11
Identities = 75/264 (28%), Positives = 100/264 (37%), Gaps = 31/264 (11%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAECKNPVLHPGECC 254
L++C Q C GT H ++ DC +EC A C+ H C
Sbjct: 185 LDECQSQP-CAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE----HNASCL 239
Query: 255 PTCLR-QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFS- 312
+CL W ECA C G R DP L + P FS
Sbjct: 240 EGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPAL-YGGVQAAFPGAFSF 298
Query: 313 --VPGECCKFCPGVDYCNMGHSCDENAT--------CMNLNTKYTCKCNQGFQGDGLTC- 361
G C PG + + G DE A+ C +L + C C G+ G TC
Sbjct: 299 RHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGP--TCE 356
Query: 362 QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCH 421
+DVDEC LHG C S+T V GY+C+C + +D V++ C+G+T
Sbjct: 357 EDVDECLSDPCLHGGTC-SDT-----VAGYICRCPETWGGRD--CSVQLTGCQGHTCPLA 408
Query: 422 ADAVCTNTPG--SYTCRCRDGYEG 443
A + G SY C C G G
Sbjct: 409 ATCIPIFESGVHSYVCHCPPGTHG 432
Score = 64.5 bits (150), Expect = 1e-09
Identities = 45/132 (34%), Positives = 55/132 (41%), Gaps = 18/132 (13%)
Query: 352 QGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV---VGGYVCQCLGGYTRKDKFNC- 407
Q + G TC + E G CH CV G+ C C+ G+ C
Sbjct: 54 QATESGGYTCGPM----EPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGP---RCE 106
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSAR 466
+++DEC CH A C N Y C C GY G TC M VDEC S C H
Sbjct: 107 LDIDECASRP--CHHGATCRNLADRYECHCPLGYA--GVTCEMEVDEC--ASAPCLHGGS 160
Query: 467 CVNIDGGFRCEC 478
C++ G FRC C
Sbjct: 161 CLDGVGSFRCVC 172
Score = 58.4 bits (135), Expect = 7e-08
Identities = 74/265 (27%), Positives = 100/265 (37%), Gaps = 36/265 (13%)
Query: 223 RCSCVHGEITCRPVECDRAECKN-PVLHPGECCPTCLR-QCLLWGNLYE--HGERFAPKE 278
RC C G R + D EC++ P H G C +C G YE H ER E
Sbjct: 169 RCVCAPGYGGTR-CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREV-LE 226
Query: 279 CAECVCHDGNMQCTRVDPELACPRLP------C--DPPQQFSVP----GECCKFCPGVDY 326
CA C + N C C P C D + S P G C + Y
Sbjct: 227 CASAPC-EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + A + C C GF+G + VDEC L+G HC +
Sbjct: 286 GGV-QAAFPGAFSFRHAAGFLCHCPPGFEGADCGVE-VDECASRPCLNGGHCQ------D 337
Query: 387 VVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+ G+ C C GY C E VDEC + C C++T Y CRC + + G
Sbjct: 338 LPNGFQCHCPDGYAGP---TCEEDVDECLSDP--CLHGGTCSDTVAGYICRCPETWGGRD 392
Query: 446 YTCMHVDECTEGSHTCHHSARCVNI 470
+ + + C HTC +A C+ I
Sbjct: 393 CS-VQLTGCQ--GHTCPLAATCIPI 414
Score = 47.2 bits (107), Expect = 2e-04
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 400 TRKDKFNCVEVDECEGNTHGCHADAVCTNT---PGSYTCRCRDGYEGDGYTCMHVDECTE 456
T + C ++ T CH A+C P + C C G++G + +DEC
Sbjct: 56 TESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRCYCVPGFQGPRCE-LDIDECA- 113
Query: 457 GSHTCHHSARCVNIDGGFRCECFTENCELSCSWQ 490
S CHH A C N+ + C C ++C +
Sbjct: 114 -SRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
Score = 37.5 bits (83), Expect = 0.15
Identities = 22/72 (30%), Positives = 27/72 (37%), Gaps = 3/72 (4%)
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C D C + ++ C C G+EG HVD C S C + DG F C C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEA-HVDPC--HSAPCARGRCHTHPDGRFECRCP 1121
Query: 480 TENCELSCSWQG 491
C W G
Sbjct: 1122 PGFGGPRCRWDG 1133
>AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein.
Length = 1176
Score = 91.9 bits (218), Expect = 6e-18
Identities = 69/207 (33%), Positives = 93/207 (44%), Gaps = 27/207 (13%)
Query: 276 PKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDE 335
P+ CA CH G + C P+ R C P Q G C+ +D C C
Sbjct: 68 PRGCATQPCHHGAL-CVPQGPDPNGFRCYCVPGFQ----GPRCEL--DIDEC-ASRPCHH 119
Query: 336 NATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQ 394
ATC NL +Y C C G+ G+TC+ +VDEC A LHG C++ VG + C
Sbjct: 120 GATCRNLADRYECHCPLGYA--GVTCETEVDECASAPCLHG------ASCLDGVGSFRCV 171
Query: 395 CLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCR-DGYEGDGYTCMHVD 452
C GY C +++DEC+ + C C + + C C GYEG + V
Sbjct: 172 CAPGY---GGTRCQLDLDECQ--SQPCAHGGTCHDLVNGFRCDCAGTGYEGT-HCEREVL 225
Query: 453 ECTEGSHTCHHSARCVNIDGGFRCECF 479
EC S C H+A C+ G FRC C+
Sbjct: 226 EC--ASAPCEHNASCLEGLGSFRCLCW 250
Score = 80.6 bits (190), Expect = 2e-14
Identities = 88/290 (30%), Positives = 112/290 (38%), Gaps = 47/290 (16%)
Query: 220 DCNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKEC 279
+C C HG TCR + DR EC P+ + G C T + +C L HG
Sbjct: 111 ECASRPCHHGA-TCRNL-ADRYECHCPLGYAGVTCETEVDECASAPCL--HGASCLDGVG 166
Query: 280 A-ECVCHDGNMQCTRVDPEL-ACPRLPC--DPPQQFSVPGECCKFCPGVDY----CN--- 328
+ CVC G TR +L C PC V G C C G Y C
Sbjct: 167 SFRCVCAPG-YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCD-CAGTGYEGTHCEREV 224
Query: 329 ---MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHC--HSNTR 383
C+ NA+C+ + C C G+ G+ L D DEC + HG C S+
Sbjct: 225 LECASAPCEHNASCLEGLGSFRCLCWPGYSGE-LCEVDEDECASSPCQHGGRCLQRSDPA 283
Query: 384 CVNVV-------------GGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNT 429
V G++C C G+ D C VEVDEC + C C +
Sbjct: 284 LYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGAD---CGVEVDECA--SRPCLNGGHCQDL 338
Query: 430 PGSYTCRCRDGYEGDGYTCMH-VDECTEGSHTCHHSARCVNIDGGFRCEC 478
P + C C DGY G TC VDEC S C H C + G+ C C
Sbjct: 339 PNGFQCHCPDGYAGP--TCEEDVDECL--SDPCLHGGTCSDTVAGYICRC 384
Score = 64.5 bits (150), Expect = 1e-09
Identities = 45/132 (34%), Positives = 55/132 (41%), Gaps = 18/132 (13%)
Query: 352 QGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV---VGGYVCQCLGGYTRKDKFNC- 407
Q + G TC + E G CH CV G+ C C+ G+ C
Sbjct: 54 QATESGGYTCGPM----EPRGCATQPCHHGALCVPQGPDPNGFRCYCVPGFQGP---RCE 106
Query: 408 VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSAR 466
+++DEC CH A C N Y C C GY G TC VDEC S C H A
Sbjct: 107 LDIDECASRP--CHHGATCRNLADRYECHCPLGYA--GVTCETEVDEC--ASAPCLHGAS 160
Query: 467 CVNIDGGFRCEC 478
C++ G FRC C
Sbjct: 161 CLDGVGSFRCVC 172
Score = 58.4 bits (135), Expect = 7e-08
Identities = 74/265 (27%), Positives = 100/265 (37%), Gaps = 36/265 (13%)
Query: 223 RCSCVHGEITCRPVECDRAECKN-PVLHPGECCPTCLR-QCLLWGNLYE--HGERFAPKE 278
RC C G R + D EC++ P H G C +C G YE H ER E
Sbjct: 169 RCVCAPGYGGTR-CQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREV-LE 226
Query: 279 CAECVCHDGNMQCTRVDPELACPRLP------C--DPPQQFSVP----GECCKFCPGVDY 326
CA C + N C C P C D + S P G C + Y
Sbjct: 227 CASAPC-EHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALY 285
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVN 386
+ + A + C C GF+G + VDEC L+G HC +
Sbjct: 286 GGV-QAAFPGAFSFRHAAGFLCHCPPGFEGADCGVE-VDECASRPCLNGGHCQ------D 337
Query: 387 VVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDG 445
+ G+ C C GY C E VDEC + C C++T Y CRC + + G
Sbjct: 338 LPNGFQCHCPDGYAGP---TCEEDVDECLSDP--CLHGGTCSDTVAGYICRCPETWGGRD 392
Query: 446 YTCMHVDECTEGSHTCHHSARCVNI 470
+ + + C HTC +A C+ I
Sbjct: 393 CS-VQLTGCQ--GHTCPLAATCIPI 414
Score = 37.5 bits (83), Expect = 0.15
Identities = 22/72 (30%), Positives = 27/72 (37%), Gaps = 3/72 (4%)
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECF 479
C D C + ++ C C G+EG HVD C S C + DG F C C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEA-HVDPC--HSAPCARGRCHTHPDGRFECRCP 1121
Query: 480 TENCELSCSWQG 491
C W G
Sbjct: 1122 PGFGGPRCRWDG 1133
Score = 33.1 bits (72), Expect = 3.2
Identities = 50/194 (25%), Positives = 66/194 (34%), Gaps = 28/194 (14%)
Query: 223 RCSCVHGEITCRPVECDRAEC-KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAE 281
RC C G + E D EC +P H G C L G F+ + A
Sbjct: 246 RCLCWPG-YSGELCEVDEDECASSPCQHGGRCLQRS-DPALYGGVQAAFPGAFSFRHAAG 303
Query: 282 CVCH-DGNMQCTRVDPEL-ACPRLPC-------DPPQQFSV---PGECCKFCP-GVDYCN 328
+CH + E+ C PC D P F G C VD C
Sbjct: 304 FLCHCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDEC- 362
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNV- 387
+ C TC + Y C+C + + G + Q + CQ GH C C+ +
Sbjct: 363 LSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQ-LTGCQ------GHTCPLAATCIPIF 415
Query: 388 ---VGGYVCQCLGG 398
V YVC C G
Sbjct: 416 ESGVHSYVCHCPPG 429
>BC131821-1|AAI31822.1| 317|Homo sapiens FRAS1 protein protein.
Length = 317
Score = 90.6 bits (215), Expect = 1e-17
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 13/159 (8%)
Query: 203 SCYSNGTVHADGATWQRD-CNRCSCVHGEITCRPVECDRAECKNPVL---HPGECCPTCL 258
SC+ +H G W C+ CSC HGE+ C P C C + L G CCP C+
Sbjct: 94 SCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCV 153
Query: 259 ---RQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP 314
+ C G++++ GE + CA+C+C +G QC C L C+ + VP
Sbjct: 154 GLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQ----CQPLFCNQDETVVRVP 209
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
G+CC C C+ E+ + N TC C++G
Sbjct: 210 GKCCPQC-SARSCSAAGQVYEHGEQWSENACTTCICDRG 247
Score = 81.4 bits (192), Expect = 9e-15
Identities = 43/126 (34%), Positives = 59/126 (46%), Gaps = 10/126 (7%)
Query: 202 KSCYSNGTVHADGATWQRD-CNRCSCVHGEITCRPVECDRAECKNP---VLHPGECCPTC 257
K C G V DG W+ C +C C +G C +C C V PG+CCP C
Sbjct: 157 KPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQC 216
Query: 258 -LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ-QFSVPG 315
R C G +YEHGE+++ C C+C G ++C + AC L C Q + G
Sbjct: 217 SARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHK----QACLPLRCGKGQSRARRHG 272
Query: 316 ECCKFC 321
+CC+ C
Sbjct: 273 QCCEEC 278
Score = 81.0 bits (191), Expect = 1e-14
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 18/164 (10%)
Query: 203 SCYSNGTVHADGATWQRD-CNRCSCVHGEIT-CRPVECDRAEC---KNPVLH--PGECCP 255
+C G++ AD W+ D C C C HG+I C+P C +C K VL +CCP
Sbjct: 27 ACVYQGSLLADATIWKPDSCQSCRC-HGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCP 85
Query: 256 TCLRQ----CLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQF 311
C+ + C ++EHG +A C+ C C+ G ++CT P+ CP L C +
Sbjct: 86 ECVLRTPGSCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCT---PQ-PCPPLSCGHQELA 141
Query: 312 SVP-GECCKFCPGVDY-CNMGHSCDENATCMNLNTKYTCKCNQG 353
+P G CC C G+ C+ ++ L+ C C G
Sbjct: 142 FIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNG 185
Score = 41.5 bits (93), Expect = 0.009
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 9/72 (12%)
Query: 197 QCDCQKSCYSNGTVHADGATWQRD-CNRCSCVHGEITCR-----PVECDRAECKNPVLHP 250
QC +SC + G V+ G W + C C C GE+ C P+ C + + +
Sbjct: 215 QCSA-RSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSR--ARRH 271
Query: 251 GECCPTCLRQCL 262
G+CC C+ L
Sbjct: 272 GQCCEECVSPAL 283
Score = 34.3 bits (75), Expect = 1.4
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 6/46 (13%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQ-CQICECLLGEVDC 597
CCP C R C H++ H G W C +C C GEV C
Sbjct: 83 CCPECVLRTPGSCHHEKKIH---EHGTEWASSPCSVCSCNHGEVRC 125
>BC131820-1|AAI31821.1| 1976|Homo sapiens FRAS1 protein protein.
Length = 1976
Score = 90.6 bits (215), Expect = 1e-17
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 13/159 (8%)
Query: 203 SCYSNGTVHADGATWQRD-CNRCSCVHGEITCRPVECDRAECKNPVL---HPGECCPTCL 258
SC+ +H G W C+ CSC HGE+ C P C C + L G CCP C+
Sbjct: 94 SCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCV 153
Query: 259 ---RQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP 314
+ C G++++ GE + CA+C+C +G QC C L C+ + VP
Sbjct: 154 GLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQ----CQPLFCNQDETVVRVP 209
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
G+CC C C+ E+ + N TC C++G
Sbjct: 210 GKCCPQC-SARSCSAAGQVYEHGEQWSENACTTCICDRG 247
Score = 81.4 bits (192), Expect = 9e-15
Identities = 43/126 (34%), Positives = 59/126 (46%), Gaps = 10/126 (7%)
Query: 202 KSCYSNGTVHADGATWQRD-CNRCSCVHGEITCRPVECDRAECKNP---VLHPGECCPTC 257
K C G V DG W+ C +C C +G C +C C V PG+CCP C
Sbjct: 157 KPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQC 216
Query: 258 -LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ-QFSVPG 315
R C G +YEHGE+++ C C+C G ++C + AC L C Q + G
Sbjct: 217 SARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHK----QACLPLRCGKGQSRARRHG 272
Query: 316 ECCKFC 321
+CC+ C
Sbjct: 273 QCCEEC 278
Score = 78.2 bits (184), Expect = 9e-14
Identities = 49/164 (29%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Query: 203 SCYSNGTVHADGATWQRD-CNRCSCVHGEIT-CRPVECDRAEC---KNPVLH--PGECCP 255
+C ++ AD W+ D C C C HG+I C+P C +C K VL +CCP
Sbjct: 27 ACVYQDSLLADATIWKPDSCQSCRC-HGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCP 85
Query: 256 TCLRQ----CLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQF 311
C+ + C ++EHG +A C+ C C+ G ++CT P+ CP L C +
Sbjct: 86 ECVLRTPGSCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCT---PQ-PCPPLSCGHQELA 141
Query: 312 SVP-GECCKFCPGVDY-CNMGHSCDENATCMNLNTKYTCKCNQG 353
+P G CC C G+ C+ ++ L+ C C G
Sbjct: 142 FIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNG 185
Score = 63.7 bits (148), Expect = 2e-09
Identities = 84/330 (25%), Positives = 121/330 (36%), Gaps = 52/330 (15%)
Query: 181 LSLKLVGAEARISRLEQC--DCQK---SCYSNGTVHADGATWQRD-CNRCSCVHGEITCR 234
L L+ ++R R QC +C SC +G V W+ C C C HG++TC+
Sbjct: 257 LPLRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQ 316
Query: 235 PVECDRAEC--KNPVLH-PGECCPTCLRQ---CL-------LWGNLYE-----HGERFAP 276
EC + EC ++H G+CCP C+ + C+ + N E GE++
Sbjct: 317 TGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWED 376
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV----DYCNMGHS 332
C C C + C E +CP P V G+CC C V D S
Sbjct: 377 GPCKVCECRGAQVTCY----EPSCPPCPVG-TLALEVKGQCCPDCTSVHCHPDCLTCSQS 431
Query: 333 ---CD--ENATCMNLNTKYTCKCNQGFQGDGLTCQDVD-ECQEAGGLHGHHCHSNTRCVN 386
CD ++ T + N C GF G C +C G C S +
Sbjct: 432 PDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLACQPQCSTC--TSGLECSSCQPPLL 489
Query: 387 VVGGYVCQCLGGYTRKDKFNCVEVDE----CEGNTH-GCHA--DAVCTNTPGSYTCRCRD 439
+ G G +D+ +C E C G T C A D + G C
Sbjct: 490 MRHGQCVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGK 549
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSA-RCV 468
G+ TC C + +C S+ RC+
Sbjct: 550 GFYNRQGTC---SACDQSCDSCGPSSPRCL 576
Score = 58.0 bits (134), Expect = 1e-07
Identities = 45/185 (24%), Positives = 76/185 (41%), Gaps = 23/185 (12%)
Query: 197 QCDCQKSCYSNGTVHADGATWQRD-CNRCSCVHGEITCR-----PVECDRAECKNPVLHP 250
QC +SC + G V+ G W + C C C GE+ C P+ C + + +
Sbjct: 215 QCSA-RSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSR--ARRH 271
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G+CC C+ C G + E + C C+C G + C + C ++ C
Sbjct: 272 GQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGE----CAKVECAR 327
Query: 308 PQQ-FSVPGECCKFCPGVD-YCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVD 365
++ + G+CC C + YC +E M+ N + +G + + C+ V
Sbjct: 328 DEELIHLDGKCCPECISRNGYC----VYEETGEFMSSNASEVKRIPEGEKWEDGPCK-VC 382
Query: 366 ECQEA 370
EC+ A
Sbjct: 383 ECRGA 387
Score = 37.1 bits (82), Expect = 0.20
Identities = 56/229 (24%), Positives = 81/229 (35%), Gaps = 35/229 (15%)
Query: 224 CSCVHGEI-TCR---PVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKEC 279
C H TC+ P C + + H G C TC L N H
Sbjct: 857 CKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDN---H--------- 904
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGEC-CKFCPGVDY----CNMGHSCD 334
VC N C D + +C C P + + GEC + C Y N CD
Sbjct: 905 ---VCQPCNTHCGSCDSQASC--TSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECD 959
Query: 335 ENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHC-HSNTRCVNVVGGYV 392
+ + + K C +C G+ C V++C + C + ++ C+ G +
Sbjct: 960 WSCSACSGPLKTDCLQCMDGYVLQDGAC--VEQCLSSFYQDSGLCKNCDSYCLQCQGPHE 1017
Query: 393 C-QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP-GSYTCRCRD 439
C +C G + + CV+ EC HA CT P G C RD
Sbjct: 1018 CTRCKGPFLLLEA-QCVQ--ECGKGYFADHAKHKCTACPQGCLQCSHRD 1063
Score = 34.3 bits (75), Expect = 1.4
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 6/46 (13%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQ-CQICECLLGEVDC 597
CCP C R C H++ H G W C +C C GEV C
Sbjct: 83 CCPECVLRTPGSCHHEKKIH---EHGTEWASSPCSVCSCNHGEVRC 125
Score = 32.7 bits (71), Expect = 4.2
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 11/57 (19%)
Query: 555 CCPHCDARY-HCRHQEMHHVTFRS---------GERWLY-QCQICECLLGEVDCWEP 600
CCP C +R +C ++E + GE+W C++CEC +V C+EP
Sbjct: 338 CCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEP 394
>BC060868-1|AAH60868.1| 685|Homo sapiens BMPER protein protein.
Length = 685
Score = 90.6 bits (215), Expect = 1e-17
Identities = 81/274 (29%), Positives = 111/274 (40%), Gaps = 47/274 (17%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRC---SCVHGEITCRPVECDRAECKNPVLHPGECC 254
C+ K C G + WQ C C G +T V C CKNP+ H G CC
Sbjct: 102 CEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCC 160
Query: 255 PTCLRQCLLWGNLYEHGERFAPK--ECAECVCHDGNMQCTR-VDPELACPR-LPCDPPQQ 310
PTC C+ G Y+ GE F P+ +C +C C G QC R V P L+CP+ L PP Q
Sbjct: 161 PTC-PGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQ 219
Query: 311 -----------FSVPGECCKFCPGVDYCNMGHSCDENAT-CMNLNTKYTCK--------C 350
F +P C F V Y N +N T C ++ CK C
Sbjct: 220 CCPKCLGQRKVFDLPFGSCLFRSDV-YDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGC 278
Query: 351 NQGFQGDGLTC------QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK 404
+QG +G C +D+ C+ G+ + + + +C C+ G T
Sbjct: 279 DQGQEGCCEECLLRVPPEDIKVCK-----FGNKIFQDGEMWSSINCTICACVKGRTECRN 333
Query: 405 FNCVEVDEC-EG---NTHGCHADAVCTNTPGSYT 434
C+ + C +G N GC +CT PG T
Sbjct: 334 KQCIPISSCPQGKILNRKGC--CPICTEKPGVCT 365
>AY324650-1|AAP89012.1| 685|Homo sapiens crossveinless-2 protein.
Length = 685
Score = 90.6 bits (215), Expect = 1e-17
Identities = 81/274 (29%), Positives = 111/274 (40%), Gaps = 47/274 (17%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRC---SCVHGEITCRPVECDRAECKNPVLHPGECC 254
C+ K C G + WQ C C G +T V C CKNP+ H G CC
Sbjct: 102 CEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCC 160
Query: 255 PTCLRQCLLWGNLYEHGERFAPK--ECAECVCHDGNMQCTR-VDPELACPR-LPCDPPQQ 310
PTC C+ G Y+ GE F P+ +C +C C G QC R V P L+CP+ L PP Q
Sbjct: 161 PTC-PGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQ 219
Query: 311 -----------FSVPGECCKFCPGVDYCNMGHSCDENAT-CMNLNTKYTCK--------C 350
F +P C F V Y N +N T C ++ CK C
Sbjct: 220 CCPKCLGQRKVFDLPFGSCLFRSDV-YDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGC 278
Query: 351 NQGFQGDGLTC------QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK 404
+QG +G C +D+ C+ G+ + + + +C C+ G T
Sbjct: 279 DQGQEGCCEECLLRVPPEDIKVCK-----FGNKIFQDGEMWSSINCTICACVKGRTECRN 333
Query: 405 FNCVEVDEC-EG---NTHGCHADAVCTNTPGSYT 434
C+ + C +G N GC +CT PG T
Sbjct: 334 KQCIPISSCPQGKILNRKGC--CPICTEKPGVCT 365
Score = 46.0 bits (104), Expect = 4e-04
Identities = 40/155 (25%), Positives = 60/155 (38%), Gaps = 15/155 (9%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD--RAECKNPVLHPGECCPTCLRQC 261
C + G V C C C++ E+TC+ +C +C + G CC C + C
Sbjct: 50 CENEGEVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQC-KGC 108
Query: 262 LLWGNLYEHGERF-APKE-CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
GN Y ++ +P E C C +G + + + C + C P + G CC
Sbjct: 109 TYEGNTYNSSFKWQSPAEPCVLRQCQEGVV----TESGVRCV-VHCKNPLEHL--GMCCP 161
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYT-CKCNQG 353
CPG + G E +K T C C G
Sbjct: 162 TCPGCVF--EGVQYQEGEEFQPEGSKCTKCSCTGG 194
>AK096150-1|BAC04712.1| 685|Homo sapiens protein ( Homo sapiens
cDNA FLJ38831 fis, clone MESAN1000126, weakly similar to
Drosophila melanogaster Crossveinless 2 (CV-2) mRNA. ).
Length = 685
Score = 90.6 bits (215), Expect = 1e-17
Identities = 81/274 (29%), Positives = 111/274 (40%), Gaps = 47/274 (17%)
Query: 198 CDCQKSCYSNGTVHADGATWQRDCNRC---SCVHGEITCRPVECDRAECKNPVLHPGECC 254
C+ K C G + WQ C C G +T V C CKNP+ H G CC
Sbjct: 102 CEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCV-VHCKNPLEHLGMCC 160
Query: 255 PTCLRQCLLWGNLYEHGERFAPK--ECAECVCHDGNMQCTR-VDPELACPR-LPCDPPQQ 310
PTC C+ G Y+ GE F P+ +C +C C G QC R V P L+CP+ L PP Q
Sbjct: 161 PTC-PGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQ 219
Query: 311 -----------FSVPGECCKFCPGVDYCNMGHSCDENAT-CMNLNTKYTCK--------C 350
F +P C F V Y N +N T C ++ CK C
Sbjct: 220 CCPKCLGQRKVFDLPFGSCLFRSDV-YDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGC 278
Query: 351 NQGFQGDGLTC------QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDK 404
+QG +G C +D+ C+ G+ + + + +C C+ G T
Sbjct: 279 DQGQEGCCEECLLRVPPEDIKVCK-----FGNKIFQDGEMWSSINCTICACVKGRTECRN 333
Query: 405 FNCVEVDEC-EG---NTHGCHADAVCTNTPGSYT 434
C+ + C +G N GC +CT PG T
Sbjct: 334 KQCIPISSCPQGKILNRKGC--CPICTEKPGVCT 365
Score = 46.0 bits (104), Expect = 4e-04
Identities = 40/155 (25%), Positives = 60/155 (38%), Gaps = 15/155 (9%)
Query: 204 CYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECD--RAECKNPVLHPGECCPTCLRQC 261
C + G V C C C++ E+TC+ +C +C + G CC C + C
Sbjct: 50 CENEGEVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQC-KGC 108
Query: 262 LLWGNLYEHGERF-APKE-CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCK 319
GN Y ++ +P E C C +G + + + C + C P + G CC
Sbjct: 109 TYEGNTYNSSFKWQSPAEPCVLRQCQEGVV----TESGVRCV-VHCKNPLEHL--GMCCP 161
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYT-CKCNQG 353
CPG + G E +K T C C G
Sbjct: 162 TCPGCVF--EGVQYQEGEEFQPEGSKCTKCSCTGG 194
>AJ512501-1|CAD54734.1| 4007|Homo sapiens extracellular matrix
protein protein.
Length = 4007
Score = 90.6 bits (215), Expect = 1e-17
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 13/159 (8%)
Query: 203 SCYSNGTVHADGATWQRD-CNRCSCVHGEITCRPVECDRAECKNPVL---HPGECCPTCL 258
SC+ +H G W C+ CSC HGE+ C P C C + L G CCP C+
Sbjct: 94 SCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCV 153
Query: 259 ---RQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP 314
+ C G++++ GE + CA+C+C +G QC C L C+ + VP
Sbjct: 154 GLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQ----CQPLFCNQDETVVRVP 209
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
G+CC C C+ E+ + N TC C++G
Sbjct: 210 GKCCPQC-SARSCSAAGQVYEHGEQWSENACTTCICDRG 247
Score = 81.4 bits (192), Expect = 9e-15
Identities = 43/126 (34%), Positives = 59/126 (46%), Gaps = 10/126 (7%)
Query: 202 KSCYSNGTVHADGATWQRD-CNRCSCVHGEITCRPVECDRAECKNP---VLHPGECCPTC 257
K C G V DG W+ C +C C +G C +C C V PG+CCP C
Sbjct: 157 KPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQC 216
Query: 258 -LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ-QFSVPG 315
R C G +YEHGE+++ C C+C G ++C + AC L C Q + G
Sbjct: 217 SARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHK----QACLPLRCGKGQSRARRHG 272
Query: 316 ECCKFC 321
+CC+ C
Sbjct: 273 QCCEEC 278
Score = 81.0 bits (191), Expect = 1e-14
Identities = 50/164 (30%), Positives = 75/164 (45%), Gaps = 18/164 (10%)
Query: 203 SCYSNGTVHADGATWQRD-CNRCSCVHGEIT-CRPVECDRAEC---KNPVLH--PGECCP 255
+C G++ AD W+ D C C C HG+I C+P C +C K VL +CCP
Sbjct: 27 ACVYQGSLLADATIWKPDSCQSCRC-HGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCP 85
Query: 256 TCLRQ----CLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQF 311
C+ + C ++EHG +A C+ C C+ G ++CT P+ CP L C +
Sbjct: 86 ECVLRTPGSCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCT---PQ-PCPPLSCGHQELA 141
Query: 312 SVP-GECCKFCPGVDY-CNMGHSCDENATCMNLNTKYTCKCNQG 353
+P G CC C G+ C+ ++ L+ C C G
Sbjct: 142 FIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNG 185
Score = 63.7 bits (148), Expect = 2e-09
Identities = 84/330 (25%), Positives = 121/330 (36%), Gaps = 52/330 (15%)
Query: 181 LSLKLVGAEARISRLEQC--DCQK---SCYSNGTVHADGATWQRD-CNRCSCVHGEITCR 234
L L+ ++R R QC +C SC +G V W+ C C C HG++TC+
Sbjct: 257 LPLRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQ 316
Query: 235 PVECDRAEC--KNPVLH-PGECCPTCLRQ---CL-------LWGNLYE-----HGERFAP 276
EC + EC ++H G+CCP C+ + C+ + N E GE++
Sbjct: 317 TGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWED 376
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGV----DYCNMGHS 332
C C C + C E +CP P V G+CC C V D S
Sbjct: 377 GPCKVCECRGAQVTCY----EPSCPPCPVG-TLALEVKGQCCPDCTSVHCHPDCLTCSQS 431
Query: 333 ---CD--ENATCMNLNTKYTCKCNQGFQGDGLTCQDVD-ECQEAGGLHGHHCHSNTRCVN 386
CD ++ T + N C GF G C +C G C S +
Sbjct: 432 PDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLACQPQCSTC--TSGLECSSCQPPLL 489
Query: 387 VVGGYVCQCLGGYTRKDKFNCVEVDE----CEGNTH-GCHA--DAVCTNTPGSYTCRCRD 439
+ G G +D+ +C E C G T C A D + G C
Sbjct: 490 MRHGQCVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGK 549
Query: 440 GYEGDGYTCMHVDECTEGSHTCHHSA-RCV 468
G+ TC C + +C S+ RC+
Sbjct: 550 GFYNRQGTC---SACDQSCDSCGPSSPRCL 576
Score = 58.0 bits (134), Expect = 1e-07
Identities = 45/185 (24%), Positives = 76/185 (41%), Gaps = 23/185 (12%)
Query: 197 QCDCQKSCYSNGTVHADGATWQRD-CNRCSCVHGEITCR-----PVECDRAECKNPVLHP 250
QC +SC + G V+ G W + C C C GE+ C P+ C + + +
Sbjct: 215 QCSA-RSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSR--ARRH 271
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G+CC C+ C G + E + C C+C G + C + C ++ C
Sbjct: 272 GQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGE----CAKVECAR 327
Query: 308 PQQ-FSVPGECCKFCPGVD-YCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVD 365
++ + G+CC C + YC +E M+ N + +G + + C+ V
Sbjct: 328 DEELIHLDGKCCPECISRNGYC----VYEETGEFMSSNASEVKRIPEGEKWEDGPCK-VC 382
Query: 366 ECQEA 370
EC+ A
Sbjct: 383 ECRGA 387
Score = 40.7 bits (91), Expect = 0.016
Identities = 56/228 (24%), Positives = 80/228 (35%), Gaps = 34/228 (14%)
Query: 224 CSCVHGEI-TCR---PVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKEC 279
C H TC+ P C + + H G C TC L N H
Sbjct: 857 CKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDN---H--------- 904
Query: 280 AECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGEC-CKFCPGVDY----CNMGHSCD 334
VC N C D + +C C P + + GEC + C Y N CD
Sbjct: 905 ---VCQPCNTHCGSCDSQASC--TSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECD 959
Query: 335 ENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVC 393
+ + + K C +C G+ C V++C + C ++ C+ G + C
Sbjct: 960 WSCSACSGPLKTDCLQCMDGYVLQDGAC--VEQCLSSFYQDSGLCKCDSYCLQCQGPHEC 1017
Query: 394 -QCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTP-GSYTCRCRD 439
+C G + + CV+ EC HA CT P G C RD
Sbjct: 1018 TRCKGPFLLLEA-QCVQ--ECGKGYFADHAKHKCTACPQGCLQCSHRD 1062
Score = 35.5 bits (78), Expect = 0.60
Identities = 55/225 (24%), Positives = 76/225 (33%), Gaps = 47/225 (20%)
Query: 284 CHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLN 343
CH C P +C CD S G C C GH D+N C N
Sbjct: 860 CHSSCRTCQGRGP-FSCSS--CDTNLVLSHTGTCSTTC------FPGHYLDDNHVCQPCN 910
Query: 344 TKYTCKCNQGFQGDGLTCQDVD------ECQEAGGLHGHHCHSNTR-----------CVN 386
T + C+ Q +C+D + ECQ ++ +T C
Sbjct: 911 T-HCGSCDS--QASCTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSG 967
Query: 387 VVGGYVCQCLGGYTRKDKFNCVE--VDECEGNTHGCHADAVCTNTPGSYTC-RCRDGYE- 442
+ QC+ GY +D CVE + ++ C D+ C G + C RC+ +
Sbjct: 968 PLKTDCLQCMDGYVLQDG-ACVEQCLSSFYQDSGLCKCDSYCLQCQGPHECTRCKGPFLL 1026
Query: 443 ---------GDGYTCMHVDE----CTEGSHTCHHSARCVNIDGGF 474
G GY H C +G C H RC D GF
Sbjct: 1027 LEAQCVQECGKGYFADHAKHKCTACPQGCLQCSHRDRCHLCDHGF 1071
Score = 34.3 bits (75), Expect = 1.4
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 6/46 (13%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQ-CQICECLLGEVDC 597
CCP C R C H++ H G W C +C C GEV C
Sbjct: 83 CCPECVLRTPGSCHHEKKIH---EHGTEWASSPCSVCSCNHGEVRC 125
Score = 32.7 bits (71), Expect = 4.2
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 11/57 (19%)
Query: 555 CCPHCDARY-HCRHQEMHHVTFRS---------GERWLY-QCQICECLLGEVDCWEP 600
CCP C +R +C ++E + GE+W C++CEC +V C+EP
Sbjct: 338 CCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEP 394
>AF193055-1|AAG22483.1| 474|Homo sapiens unknown protein.
Length = 474
Score = 90.6 bits (215), Expect = 1e-17
Identities = 48/149 (32%), Positives = 78/149 (52%), Gaps = 25/149 (16%)
Query: 326 YCNMGHSCDENATCMN------LNTKYTCK---------C-NQGFQ--GDGLTCQDVDEC 367
+C GH +ATC+N +N +Y+C+ C + G + +G C D+DEC
Sbjct: 40 FCLSGHMLMPDATCVNSRTCAMINCQYSCEDTEEGPQCLCPSSGLRLAPNGRDCLDIDEC 99
Query: 368 QEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRK---DKFNCVEVDECEGNTHGCHADA 424
+ C N RCVN G Y C+C G+ + +++C++++EC ++H C A
Sbjct: 100 ASGKVI----CPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDINECTMDSHTCSHHA 155
Query: 425 VCTNTPGSYTCRCRDGYEGDGYTCMHVDE 453
C NT GS+ C+C+ GY+G+G C + E
Sbjct: 156 NCFNTQGSFKCKCKQGYKGNGLRCSAIPE 184
Score = 83.4 bits (197), Expect = 2e-15
Identities = 47/147 (31%), Positives = 66/147 (44%), Gaps = 15/147 (10%)
Query: 339 CMNLNTKYTCKCNQGFQ-GDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLG 397
C+N + Y C C G TC + C +C + C + G C C
Sbjct: 30 CVNTHGSYKCFCLSGHMLMPDATCVNSRTCAMI------NCQYS--CEDTEEGPQCLCPS 81
Query: 398 GYTR--KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE----GDGYTCMHV 451
R + +C+++DEC C + C NT GSY C+C G+E Y C+ +
Sbjct: 82 SGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYYCKCHIGFELQYISGRYDCIDI 141
Query: 452 DECTEGSHTCHHSARCVNIDGGFRCEC 478
+ECT SHTC H A C N G F+C+C
Sbjct: 142 NECTMDSHTCSHHANCFNTQGSFKCKC 168
Score = 66.1 bits (154), Expect = 4e-10
Identities = 41/123 (33%), Positives = 52/123 (42%), Gaps = 14/123 (11%)
Query: 360 TC-QDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTH 418
TC QDV+EC G+ C RCVN G Y C CL G+ CV C
Sbjct: 11 TCSQDVNEC----GMKPRPCQH--RCVNTHGSYKCFCLSGHMLMPDATCVNSRTCA--MI 62
Query: 419 GCHADAVCTNTPGSYTCRCRDG---YEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFR 475
C C +T C C +G C+ +DEC G C ++ RCVN G +
Sbjct: 63 NCQYS--CEDTEEGPQCLCPSSGLRLAPNGRDCLDIDECASGKVICPYNRRCVNTFGSYY 120
Query: 476 CEC 478
C+C
Sbjct: 121 CKC 123
>AC131945-1|AAY41027.1| 475|Homo sapiens unknown protein.
Length = 475
Score = 90.6 bits (215), Expect = 1e-17
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 13/159 (8%)
Query: 203 SCYSNGTVHADGATWQRD-CNRCSCVHGEITCRPVECDRAECKNPVL---HPGECCPTCL 258
SC+ +H G W C+ CSC HGE+ C P C C + L G CCP C+
Sbjct: 58 SCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCV 117
Query: 259 ---RQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP 314
+ C G++++ GE + CA+C+C +G QC C L C+ + VP
Sbjct: 118 GLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQ----CQPLFCNQDETVVRVP 173
Query: 315 GECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQG 353
G+CC C C+ E+ + N TC C++G
Sbjct: 174 GKCCPQC-SARSCSAAGQVYEHGEQWSENACTTCICDRG 211
Score = 81.4 bits (192), Expect = 9e-15
Identities = 43/126 (34%), Positives = 59/126 (46%), Gaps = 10/126 (7%)
Query: 202 KSCYSNGTVHADGATWQRD-CNRCSCVHGEITCRPVECDRAECKNP---VLHPGECCPTC 257
K C G V DG W+ C +C C +G C +C C V PG+CCP C
Sbjct: 121 KPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQC 180
Query: 258 -LRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ-QFSVPG 315
R C G +YEHGE+++ C C+C G ++C + AC L C Q + G
Sbjct: 181 SARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHK----QACLPLRCGKGQSRARRHG 236
Query: 316 ECCKFC 321
+CC+ C
Sbjct: 237 QCCEEC 242
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/154 (30%), Positives = 69/154 (44%), Gaps = 18/154 (11%)
Query: 213 DGATWQRD-CNRCSCVHGEIT-CRPVECDRAEC---KNPVLH--PGECCPTCLRQ----C 261
D W+ D C C C HG+I C+P C +C K VL +CCP C+ + C
Sbjct: 1 DATIWKPDSCQSCRC-HGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSC 59
Query: 262 LLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVP-GECCKF 320
++EHG +A C+ C C+ G ++CT P+ CP L C + +P G CC
Sbjct: 60 HHEKKIHEHGTEWASSPCSVCSCNHGEVRCT---PQ-PCPPLSCGHQELAFIPEGSCCPV 115
Query: 321 CPGVDY-CNMGHSCDENATCMNLNTKYTCKCNQG 353
C G+ C+ ++ L+ C C G
Sbjct: 116 CVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNG 149
Score = 62.9 bits (146), Expect = 3e-09
Identities = 49/172 (28%), Positives = 73/172 (42%), Gaps = 30/172 (17%)
Query: 181 LSLKLVGAEARISRLEQC--DCQK---SCYSNGTVHADGATWQRD-CNRCSCVHGEITCR 234
L L+ ++R R QC +C SC +G V W+ C C C HG++TC+
Sbjct: 221 LPLRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQ 280
Query: 235 PVECDRAEC--KNPVLH-PGECCPTCLRQ---CL-------LWGNLYE-----HGERFAP 276
EC + EC ++H G+CCP C+ + C+ + N E GE++
Sbjct: 281 TGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWED 340
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCN 328
C C C + C E +CP P V G+CC C V +C+
Sbjct: 341 GPCKVCECRGAQVTCY----EPSCPPCPVG-TLALEVKGQCCPDCTSV-HCH 386
Score = 58.0 bits (134), Expect = 1e-07
Identities = 45/185 (24%), Positives = 76/185 (41%), Gaps = 23/185 (12%)
Query: 197 QCDCQKSCYSNGTVHADGATWQRD-CNRCSCVHGEITCR-----PVECDRAECKNPVLHP 250
QC +SC + G V+ G W + C C C GE+ C P+ C + + +
Sbjct: 179 QCSA-RSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSR--ARRH 235
Query: 251 GECCPTCLR---QCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDP 307
G+CC C+ C G + E + C C+C G + C + C ++ C
Sbjct: 236 GQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGE----CAKVECAR 291
Query: 308 PQQ-FSVPGECCKFCPGVD-YCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVD 365
++ + G+CC C + YC +E M+ N + +G + + C+ V
Sbjct: 292 DEELIHLDGKCCPECISRNGYC----VYEETGEFMSSNASEVKRIPEGEKWEDGPCK-VC 346
Query: 366 ECQEA 370
EC+ A
Sbjct: 347 ECRGA 351
Score = 34.3 bits (75), Expect = 1.4
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 6/46 (13%)
Query: 555 CCPHCDARY--HCRHQEMHHVTFRSGERWLYQ-CQICECLLGEVDC 597
CCP C R C H++ H G W C +C C GEV C
Sbjct: 47 CCPECVLRTPGSCHHEKKIH---EHGTEWASSPCSVCSCNHGEVRC 89
Score = 32.7 bits (71), Expect = 4.2
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 11/57 (19%)
Query: 555 CCPHCDARY-HCRHQEMHHVTFRS---------GERWLY-QCQICECLLGEVDCWEP 600
CCP C +R +C ++E + GE+W C++CEC +V C+EP
Sbjct: 302 CCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEP 358
>BC060770-1|AAH60770.2| 757|Homo sapiens SUSD1 protein protein.
Length = 757
Score = 89.8 bits (213), Expect = 3e-17
Identities = 51/130 (39%), Positives = 64/130 (49%), Gaps = 14/130 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHS 380
PG D ++ +C E+ATC K C CN GF G+G T C D +ECQ L C +
Sbjct: 31 PGPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATL---VCGN 87
Query: 381 NTRCVNVVGGYVCQCLGGYTR---------KDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+T C N GG+ C CL GY D C ++DECE + C C NT G
Sbjct: 88 HTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL-CRHGGRCVNTHG 146
Query: 432 SYTCRCRDGY 441
S+ C C DGY
Sbjct: 147 SFECYCMDGY 156
Score = 81.0 bits (191), Expect = 1e-14
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CH + C G +C C G+ + CV+ +EC+ G T C C NTPG + C
Sbjct: 42 CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI 101
Query: 437 CRDGYEG----------DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +GY DG C +DEC E S C H RCVN G F C C
Sbjct: 102 CLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVNTHGSFECYC 152
Score = 32.7 bits (71), Expect = 4.2
Identities = 10/35 (28%), Positives = 16/35 (45%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
FC +D C + C C+N + + C C G+
Sbjct: 122 FCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY 156
>AY358746-1|AAQ89106.1| 747|Homo sapiens GRGP2438 protein.
Length = 747
Score = 89.8 bits (213), Expect = 3e-17
Identities = 51/130 (39%), Positives = 64/130 (49%), Gaps = 14/130 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHS 380
PG D ++ +C E+ATC K C CN GF G+G T C D +ECQ L C +
Sbjct: 31 PGPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATL---VCGN 87
Query: 381 NTRCVNVVGGYVCQCLGGYTR---------KDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+T C N GG+ C CL GY D C ++DECE + C C NT G
Sbjct: 88 HTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL-CRHGGRCVNTHG 146
Query: 432 SYTCRCRDGY 441
S+ C C DGY
Sbjct: 147 SFECYCMDGY 156
Score = 81.0 bits (191), Expect = 1e-14
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CH + C G +C C G+ + CV+ +EC+ G T C C NTPG + C
Sbjct: 42 CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI 101
Query: 437 CRDGYEG----------DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +GY DG C +DEC E S C H RCVN G F C C
Sbjct: 102 CLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVNTHGSFECYC 152
Score = 32.7 bits (71), Expect = 4.2
Identities = 10/35 (28%), Positives = 16/35 (45%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
FC +D C + C C+N + + C C G+
Sbjct: 122 FCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY 156
>AL158824-3|CAI12348.2| 705|Homo sapiens sushi domain containing 1
protein.
Length = 705
Score = 89.8 bits (213), Expect = 3e-17
Identities = 51/130 (39%), Positives = 64/130 (49%), Gaps = 14/130 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHS 380
PG D ++ +C E+ATC K C CN GF G+G T C D +ECQ L C +
Sbjct: 14 PGPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATL---VCGN 70
Query: 381 NTRCVNVVGGYVCQCLGGYTR---------KDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+T C N GG+ C CL GY D C ++DECE + C C NT G
Sbjct: 71 HTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL-CRHGGRCVNTHG 129
Query: 432 SYTCRCRDGY 441
S+ C C DGY
Sbjct: 130 SFECYCMDGY 139
Score = 81.0 bits (191), Expect = 1e-14
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CH + C G +C C G+ + CV+ +EC+ G T C C NTPG + C
Sbjct: 25 CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI 84
Query: 437 CRDGYEG----------DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +GY DG C +DEC E S C H RCVN G F C C
Sbjct: 85 CLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVNTHGSFECYC 135
Score = 32.7 bits (71), Expect = 4.2
Identities = 10/35 (28%), Positives = 16/35 (45%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
FC +D C + C C+N + + C C G+
Sbjct: 105 FCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY 139
>AL158824-2|CAI12347.2| 747|Homo sapiens sushi domain containing 1
protein.
Length = 747
Score = 89.8 bits (213), Expect = 3e-17
Identities = 51/130 (39%), Positives = 64/130 (49%), Gaps = 14/130 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHS 380
PG D ++ +C E+ATC K C CN GF G+G T C D +ECQ L C +
Sbjct: 31 PGPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATL---VCGN 87
Query: 381 NTRCVNVVGGYVCQCLGGYTR---------KDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+T C N GG+ C CL GY D C ++DECE + C C NT G
Sbjct: 88 HTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL-CRHGGRCVNTHG 146
Query: 432 SYTCRCRDGY 441
S+ C C DGY
Sbjct: 147 SFECYCMDGY 156
Score = 81.0 bits (191), Expect = 1e-14
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CH + C G +C C G+ + CV+ +EC+ G T C C NTPG + C
Sbjct: 42 CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI 101
Query: 437 CRDGYEG----------DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +GY DG C +DEC E S C H RCVN G F C C
Sbjct: 102 CLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVNTHGSFECYC 152
Score = 32.7 bits (71), Expect = 4.2
Identities = 10/35 (28%), Positives = 16/35 (45%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
FC +D C + C C+N + + C C G+
Sbjct: 122 FCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY 156
>AL138756-2|CAI95300.2| 705|Homo sapiens sushi domain containing 1
protein.
Length = 705
Score = 89.8 bits (213), Expect = 3e-17
Identities = 51/130 (39%), Positives = 64/130 (49%), Gaps = 14/130 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHS 380
PG D ++ +C E+ATC K C CN GF G+G T C D +ECQ L C +
Sbjct: 14 PGPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATL---VCGN 70
Query: 381 NTRCVNVVGGYVCQCLGGYTR---------KDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+T C N GG+ C CL GY D C ++DECE + C C NT G
Sbjct: 71 HTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL-CRHGGRCVNTHG 129
Query: 432 SYTCRCRDGY 441
S+ C C DGY
Sbjct: 130 SFECYCMDGY 139
Score = 81.0 bits (191), Expect = 1e-14
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CH + C G +C C G+ + CV+ +EC+ G T C C NTPG + C
Sbjct: 25 CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI 84
Query: 437 CRDGYEG----------DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +GY DG C +DEC E S C H RCVN G F C C
Sbjct: 85 CLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVNTHGSFECYC 135
Score = 32.7 bits (71), Expect = 4.2
Identities = 10/35 (28%), Positives = 16/35 (45%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
FC +D C + C C+N + + C C G+
Sbjct: 105 FCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY 139
>AL138756-1|CAI95299.2| 747|Homo sapiens sushi domain containing 1
protein.
Length = 747
Score = 89.8 bits (213), Expect = 3e-17
Identities = 51/130 (39%), Positives = 64/130 (49%), Gaps = 14/130 (10%)
Query: 322 PGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT-CQDVDECQEAGGLHGHHCHS 380
PG D ++ +C E+ATC K C CN GF G+G T C D +ECQ L C +
Sbjct: 31 PGPDGLDVCATCHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATL---VCGN 87
Query: 381 NTRCVNVVGGYVCQCLGGYTR---------KDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+T C N GG+ C CL GY D C ++DECE + C C NT G
Sbjct: 88 HTSCHNTPGGFYCICLEGYRATNNNKTFIPNDGTFCTDIDECEVSGL-CRHGGRCVNTHG 146
Query: 432 SYTCRCRDGY 441
S+ C C DGY
Sbjct: 147 SFECYCMDGY 156
Score = 81.0 bits (191), Expect = 1e-14
Identities = 41/112 (36%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 378 CHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECE-GNTHGCHADAVCTNTPGSYTCR 436
CH + C G +C C G+ + CV+ +EC+ G T C C NTPG + C
Sbjct: 42 CHEHATCQQREGKKICICNYGFVGNGRTQCVDKNECQFGATLVCGNHTSCHNTPGGFYCI 101
Query: 437 CRDGYEG----------DGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C +GY DG C +DEC E S C H RCVN G F C C
Sbjct: 102 CLEGYRATNNNKTFIPNDGTFCTDIDEC-EVSGLCRHGGRCVNTHGSFECYC 152
Score = 32.7 bits (71), Expect = 4.2
Identities = 10/35 (28%), Positives = 16/35 (45%)
Query: 320 FCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGF 354
FC +D C + C C+N + + C C G+
Sbjct: 122 FCTDIDECEVSGLCRHGGRCVNTHGSFECYCMDGY 156
>X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA for
protein S. ).
Length = 650
Score = 89.0 bits (211), Expect = 5e-17
Identities = 51/152 (33%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Query: 333 CDENA--TCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVG 389
C+E+ +C + +TC C G+QG+ C+ D++EC++ ++G C + C N G
Sbjct: 100 CNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGG-C--SQICDNTPG 154
Query: 390 GYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GY 446
Y C C G+ +K +C +VDEC C AVC N G + C C +GY +
Sbjct: 155 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNILGDFECECPEGYRYNLKSK 213
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +DEC+E + C + CVN GG C C
Sbjct: 214 SCEDIDECSE--NMC--AQLCVNYPGGHTCYC 241
Score = 52.8 bits (121), Expect = 4e-06
Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C VD C++ S A C N+ + C+C +G++ + +C+D+DEC E +
Sbjct: 171 KDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSE------N 224
Query: 377 HCHSNTRCVNVVGGYVCQCLG--GY-TRKDKFNCVEVDEC 413
C CVN GG+ C C G G+ +D+ +C V C
Sbjct: 225 MCAQ--LCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
>M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein.
Length = 650
Score = 89.0 bits (211), Expect = 5e-17
Identities = 51/152 (33%), Positives = 78/152 (51%), Gaps = 16/152 (10%)
Query: 333 CDENA--TCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVG 389
C+E+ +C + +TC C G+QG+ C+ D++EC++ ++G C + C N G
Sbjct: 100 CNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGG-C--SQICDNTPG 154
Query: 390 GYVCQCLGGYTR-KDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGD--GY 446
Y C C G+ +K +C +VDEC C AVC N G + C C +GY +
Sbjct: 155 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNILGDFECECPEGYRYNLKSK 213
Query: 447 TCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
+C +DEC+E + C + CVN GG C C
Sbjct: 214 SCEDIDECSE--NMC--AQLCVNYPGGHTCYC 241
Score = 52.8 bits (121), Expect = 4e-06
Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 319 KFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGD--GLTCQDVDECQEAGGLHGH 376
K C VD C++ S A C N+ + C+C +G++ + +C+D+DEC E +
Sbjct: 171 KDCKDVDECSLKPSICGTAVCKNILGDFECECPEGYRYNLKSKSCEDIDECSE------N 224
Query: 377 HCHSNTRCVNVVGGYVCQCLG--GY-TRKDKFNCVEVDEC 413
C CVN GG+ C C G G+ +D+ +C V C
Sbjct: 225 MCAQ--LCVNYPGGHTCYCDGKKGFKLAQDQKSCEVVSVC 262
>L38969-1|AAC41762.1| 956|Homo sapiens thrombospondin 3 protein.
Length = 956
Score = 88.2 bits (209), Expect = 8e-17
Identities = 57/184 (30%), Positives = 85/184 (46%), Gaps = 27/184 (14%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTK--YTC-KCNQGFQGDGLTCQDVDECQEAGG 372
+ C F +C+ + C CM + Y C C G QG+G C D++EC
Sbjct: 267 QVCGFHEQRSHCSP-NPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECA---- 321
Query: 373 LHGHHCHSNTRCVNVVGGYVCQ-CLGGY------------TRKDKFNCVEVDEC-EGNTH 418
H C + C+N + G+ C+ C GY R K C ++DEC +GN
Sbjct: 322 -HADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNG 380
Query: 419 GCHADAVCTNTPGSYTC-RCRDGYEGD-GYTCMHVDECTEGSHT-CHHSARCV-NIDGGF 474
GC +++CTNT GS+ C CR G+ G+ C+ C +H+ CH A C+ +G
Sbjct: 381 GCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERNGAV 440
Query: 475 RCEC 478
C+C
Sbjct: 441 SCQC 444
Score = 64.9 bits (151), Expect = 9e-10
Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 20/145 (13%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLT-------------CQDVDE 366
C ++ C C ++C+N + C+ C +G++G ++ C D+DE
Sbjct: 314 CSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDE 373
Query: 367 CQEAGGLHGHHCHSNTRCVNVVGGYVC-QCLGGYTRKDKFNCVEVDECEGNTHG-CHADA 424
C + G +G C N+ C N VG + C C G+ C+ C H CH A
Sbjct: 374 CND--GNNGG-CDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHA 430
Query: 425 VCT-NTPGSYTCRCRDGYEGDGYTC 448
C G+ +C+C G+ G+G C
Sbjct: 431 HCLFERNGAVSCQCNVGWAGNGNVC 455
Score = 58.4 bits (135), Expect = 7e-08
Identities = 92/379 (24%), Positives = 138/379 (36%), Gaps = 32/379 (8%)
Query: 40 RYLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQAT-----LY 94
R+LE G+ ++V + Y G V LADG H V L + G LY
Sbjct: 83 RWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTVLLRLRGPSRPSPALHLY 142
Query: 95 VDCHLLYRRLIPPPDRNFTQPQLT-LWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPG 153
VDC L + P ++ L I + +G ++ ++++ G G +A+
Sbjct: 143 VDCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRMQGFVESMKIILG--GSMARVGA 200
Query: 154 LDSECPTCGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHAD 213
L SECP G ++ A L + + + + LV +++ + + +
Sbjct: 201 L-SECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQI-LVELRDDIRDQVKEMSL 258
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDR-AECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
+C C C P C R +C +PG C C L GN +
Sbjct: 259 IRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPG--LQGNGTHCSD 316
Query: 273 RFAPKECAEC-VCHDGNMQCTRVDPELACPRLPCD-PPQQFSVPG-----ECCKFCPGVD 325
ECA C G+ C P C P Q S G + C +D
Sbjct: 317 ---INECAHADPCFPGS-SCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDID 372
Query: 326 YCNMGHS--CDENATCMNLNTKYTC-KCNQGFQGD-GLTCQDVDECQEAGGLHGHHCHSN 381
CN G++ CD N+ C N + C C GF G+ C C H CH +
Sbjct: 373 ECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPA--HS-PCHIH 429
Query: 382 TRCVNVVGGYV-CQCLGGY 399
C+ G V CQC G+
Sbjct: 430 AHCLFERNGAVSCQCNVGW 448
>BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3,
precursor protein.
Length = 956
Score = 88.2 bits (209), Expect = 8e-17
Identities = 57/184 (30%), Positives = 85/184 (46%), Gaps = 27/184 (14%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTK--YTC-KCNQGFQGDGLTCQDVDECQEAGG 372
+ C F +C+ + C CM + Y C C G QG+G C D++EC
Sbjct: 267 QVCGFHEQRSHCSP-NPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECA---- 321
Query: 373 LHGHHCHSNTRCVNVVGGYVCQ-CLGGY------------TRKDKFNCVEVDEC-EGNTH 418
H C + C+N + G+ C+ C GY R K C ++DEC +GN
Sbjct: 322 -HADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNG 380
Query: 419 GCHADAVCTNTPGSYTC-RCRDGYEGD-GYTCMHVDECTEGSHT-CHHSARCV-NIDGGF 474
GC +++CTNT GS+ C CR G+ G+ C+ C +H+ CH A C+ +G
Sbjct: 381 GCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERNGAV 440
Query: 475 RCEC 478
C+C
Sbjct: 441 SCQC 444
Score = 64.9 bits (151), Expect = 9e-10
Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 20/145 (13%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLT-------------CQDVDE 366
C ++ C C ++C+N + C+ C +G++G ++ C D+DE
Sbjct: 314 CSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDE 373
Query: 367 CQEAGGLHGHHCHSNTRCVNVVGGYVC-QCLGGYTRKDKFNCVEVDECEGNTHG-CHADA 424
C + G +G C N+ C N VG + C C G+ C+ C H CH A
Sbjct: 374 CND--GNNGG-CDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHA 430
Query: 425 VCT-NTPGSYTCRCRDGYEGDGYTC 448
C G+ +C+C G+ G+G C
Sbjct: 431 HCLFERNGAVSCQCNVGWAGNGNVC 455
Score = 58.4 bits (135), Expect = 7e-08
Identities = 92/379 (24%), Positives = 138/379 (36%), Gaps = 32/379 (8%)
Query: 40 RYLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQAT-----LY 94
R+LE G+ ++V + Y G V LADG H V L + G LY
Sbjct: 83 RWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTVLLRLRGPSRPSPALHLY 142
Query: 95 VDCHLLYRRLIPPPDRNFTQPQLT-LWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPG 153
VDC L + P ++ L I + +G ++ ++++ G G +A+
Sbjct: 143 VDCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRMQGFVESMKIILG--GSMARVGA 200
Query: 154 LDSECPTCGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHAD 213
L SECP G ++ A L + + + + LV +++ + + +
Sbjct: 201 L-SECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQI-LVELRDDIRDQVKEMSL 258
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDR-AECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
+C C C P C R +C +PG C C L GN +
Sbjct: 259 IRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPG--LQGNGTHCSD 316
Query: 273 RFAPKECAEC-VCHDGNMQCTRVDPELACPRLPCD-PPQQFSVPG-----ECCKFCPGVD 325
ECA C G+ C P C P Q S G + C +D
Sbjct: 317 ---INECAHADPCFPGS-SCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDID 372
Query: 326 YCNMGHS--CDENATCMNLNTKYTC-KCNQGFQGD-GLTCQDVDECQEAGGLHGHHCHSN 381
CN G++ CD N+ C N + C C GF G+ C C H CH +
Sbjct: 373 ECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPA--HS-PCHIH 429
Query: 382 TRCVNVVGGYV-CQCLGGY 399
C+ G V CQC G+
Sbjct: 430 AHCLFERNGAVSCQCNVGW 448
>AL713999-15|CAI95084.1| 956|Homo sapiens thrombospondin 3 protein.
Length = 956
Score = 88.2 bits (209), Expect = 8e-17
Identities = 57/184 (30%), Positives = 85/184 (46%), Gaps = 27/184 (14%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTK--YTC-KCNQGFQGDGLTCQDVDECQEAGG 372
+ C F +C+ + C CM + Y C C G QG+G C D++EC
Sbjct: 267 QVCGFHEQRSHCSP-NPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECA---- 321
Query: 373 LHGHHCHSNTRCVNVVGGYVCQ-CLGGY------------TRKDKFNCVEVDEC-EGNTH 418
H C + C+N + G+ C+ C GY R K C ++DEC +GN
Sbjct: 322 -HADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNG 380
Query: 419 GCHADAVCTNTPGSYTC-RCRDGYEGD-GYTCMHVDECTEGSHT-CHHSARCV-NIDGGF 474
GC +++CTNT GS+ C CR G+ G+ C+ C +H+ CH A C+ +G
Sbjct: 381 GCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERNGAV 440
Query: 475 RCEC 478
C+C
Sbjct: 441 SCQC 444
Score = 64.9 bits (151), Expect = 9e-10
Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 20/145 (13%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLT-------------CQDVDE 366
C ++ C C ++C+N + C+ C +G++G ++ C D+DE
Sbjct: 314 CSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDE 373
Query: 367 CQEAGGLHGHHCHSNTRCVNVVGGYVC-QCLGGYTRKDKFNCVEVDECEGNTHG-CHADA 424
C + G +G C N+ C N VG + C C G+ C+ C H CH A
Sbjct: 374 CND--GNNGG-CDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHA 430
Query: 425 VCT-NTPGSYTCRCRDGYEGDGYTC 448
C G+ +C+C G+ G+G C
Sbjct: 431 HCLFERNGAVSCQCNVGWAGNGNVC 455
Score = 58.4 bits (135), Expect = 7e-08
Identities = 92/379 (24%), Positives = 138/379 (36%), Gaps = 32/379 (8%)
Query: 40 RYLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQAT-----LY 94
R+LE G+ ++V + Y G V LADG H V L + G LY
Sbjct: 83 RWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTVLLRLRGPSRPSPALHLY 142
Query: 95 VDCHLLYRRLIPPPDRNFTQPQLT-LWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPG 153
VDC L + P ++ L I + +G ++ ++++ G G +A+
Sbjct: 143 VDCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRMQGFVESMKIILG--GSMARVGA 200
Query: 154 LDSECPTCGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHAD 213
L SECP G ++ A L + + + + LV +++ + + +
Sbjct: 201 L-SECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQI-LVELRDDIRDQVKEMSL 258
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDR-AECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
+C C C P C R +C +PG C C L GN +
Sbjct: 259 IRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPG--LQGNGTHCSD 316
Query: 273 RFAPKECAEC-VCHDGNMQCTRVDPELACPRLPCD-PPQQFSVPG-----ECCKFCPGVD 325
ECA C G+ C P C P Q S G + C +D
Sbjct: 317 ---INECAHADPCFPGS-SCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDID 372
Query: 326 YCNMGHS--CDENATCMNLNTKYTC-KCNQGFQGD-GLTCQDVDECQEAGGLHGHHCHSN 381
CN G++ CD N+ C N + C C GF G+ C C H CH +
Sbjct: 373 ECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPA--HS-PCHIH 429
Query: 382 TRCVNVVGGYV-CQCLGGY 399
C+ G V CQC G+
Sbjct: 430 AHCLFERNGAVSCQCNVGW 448
>AK223278-1|BAD96998.1| 956|Homo sapiens thrombospondin 3 precursor
variant protein.
Length = 956
Score = 88.2 bits (209), Expect = 8e-17
Identities = 57/184 (30%), Positives = 85/184 (46%), Gaps = 27/184 (14%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTK--YTC-KCNQGFQGDGLTCQDVDECQEAGG 372
+ C F +C+ + C CM + Y C C G QG+G C D++EC
Sbjct: 267 QVCGFHEQRSHCSP-NPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECA---- 321
Query: 373 LHGHHCHSNTRCVNVVGGYVCQ-CLGGY------------TRKDKFNCVEVDEC-EGNTH 418
H C + C+N + G+ C+ C GY R K C ++DEC +GN
Sbjct: 322 -HADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNG 380
Query: 419 GCHADAVCTNTPGSYTC-RCRDGYEGD-GYTCMHVDECTEGSHT-CHHSARCV-NIDGGF 474
GC +++CTNT GS+ C CR G+ G+ C+ C +H+ CH A C+ +G
Sbjct: 381 GCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERNGAV 440
Query: 475 RCEC 478
C+C
Sbjct: 441 SCQC 444
Score = 64.9 bits (151), Expect = 9e-10
Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 20/145 (13%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLT-------------CQDVDE 366
C ++ C C ++C+N + C+ C +G++G ++ C D+DE
Sbjct: 314 CSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDE 373
Query: 367 CQEAGGLHGHHCHSNTRCVNVVGGYVC-QCLGGYTRKDKFNCVEVDECEGNTHG-CHADA 424
C + G +G C N+ C N VG + C C G+ C+ C H CH A
Sbjct: 374 CND--GNNGG-CDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHA 430
Query: 425 VCT-NTPGSYTCRCRDGYEGDGYTC 448
C G+ +C+C G+ G+G C
Sbjct: 431 HCLFERNGAVSCQCNVGWAGNGNVC 455
Score = 56.4 bits (130), Expect = 3e-07
Identities = 91/379 (24%), Positives = 138/379 (36%), Gaps = 32/379 (8%)
Query: 40 RYLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQAT-----LY 94
R+LE G+ ++V + Y G V LADG H V L + G LY
Sbjct: 83 RWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTVLLRLRGPSRPSPALHLY 142
Query: 95 VDCHLLYRRLIPPPDRNFTQPQLT-LWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPG 153
V+C L + P ++ L I + +G ++ ++++ G G +A+
Sbjct: 143 VNCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRMQGFVESMKIILG--GSMARVGA 200
Query: 154 LDSECPTCGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHAD 213
L SECP G ++ A L + + + + LV +++ + + +
Sbjct: 201 L-SECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQI-LVELRDDIRDQVKEMSL 258
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDR-AECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
+C C C P C R +C +PG C C L GN +
Sbjct: 259 IRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPG--LQGNGTHCSD 316
Query: 273 RFAPKECAEC-VCHDGNMQCTRVDPELACPRLPCD-PPQQFSVPG-----ECCKFCPGVD 325
ECA C G+ C P C P Q S G + C +D
Sbjct: 317 ---INECAHADPCFPGS-SCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDID 372
Query: 326 YCNMGHS--CDENATCMNLNTKYTC-KCNQGFQGD-GLTCQDVDECQEAGGLHGHHCHSN 381
CN G++ CD N+ C N + C C GF G+ C C H CH +
Sbjct: 373 ECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPA--HS-PCHIH 429
Query: 382 TRCVNVVGGYV-CQCLGGY 399
C+ G V CQC G+
Sbjct: 430 AHCLFERNGAVSCQCNVGW 448
>AF023268-6|AAC51818.1| 736|Homo sapiens thrombospondin3 protein.
Length = 736
Score = 88.2 bits (209), Expect = 8e-17
Identities = 57/184 (30%), Positives = 85/184 (46%), Gaps = 27/184 (14%)
Query: 316 ECCKFCPGVDYCNMGHSCDENATCMNLNTK--YTC-KCNQGFQGDGLTCQDVDECQEAGG 372
+ C F +C+ + C CM + Y C C G QG+G C D++EC
Sbjct: 267 QVCGFHEQRSHCSP-NPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECA---- 321
Query: 373 LHGHHCHSNTRCVNVVGGYVCQ-CLGGY------------TRKDKFNCVEVDEC-EGNTH 418
H C + C+N + G+ C+ C GY R K C ++DEC +GN
Sbjct: 322 -HADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNG 380
Query: 419 GCHADAVCTNTPGSYTC-RCRDGYEGD-GYTCMHVDECTEGSHT-CHHSARCV-NIDGGF 474
GC +++CTNT GS+ C CR G+ G+ C+ C +H+ CH A C+ +G
Sbjct: 381 GCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERNGAV 440
Query: 475 RCEC 478
C+C
Sbjct: 441 SCQC 444
Score = 64.9 bits (151), Expect = 9e-10
Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 20/145 (13%)
Query: 321 CPGVDYCNMGHSCDENATCMNLNTKYTCK-CNQGFQGDGLT-------------CQDVDE 366
C ++ C C ++C+N + C+ C +G++G ++ C D+DE
Sbjct: 314 CSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDE 373
Query: 367 CQEAGGLHGHHCHSNTRCVNVVGGYVC-QCLGGYTRKDKFNCVEVDECEGNTHG-CHADA 424
C + G +G C N+ C N VG + C C G+ C+ C H CH A
Sbjct: 374 CND--GNNGG-CDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHA 430
Query: 425 VCT-NTPGSYTCRCRDGYEGDGYTC 448
C G+ +C+C G+ G+G C
Sbjct: 431 HCLFERNGAVSCQCNVGWAGNGNVC 455
Score = 58.4 bits (135), Expect = 7e-08
Identities = 92/379 (24%), Positives = 138/379 (36%), Gaps = 32/379 (8%)
Query: 40 RYLEVQSSGRRDEVRLHYVAAGGAAPRVETFPFRLADGSWHRVALSVSGAQAT-----LY 94
R+LE G+ ++V + Y G V LADG H V L + G LY
Sbjct: 83 RWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTVLLRLRGPSRPSPALHLY 142
Query: 95 VDCHLLYRRLIPPPDRNFTQPQLT-LWIGQRNNKHSLFKGALQEVRLVSGPHGYLAQCPG 153
VDC L + P ++ L I + +G ++ ++++ G G +A+
Sbjct: 143 VDCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRMQGFVESMKIILG--GSMARVGA 200
Query: 154 LDSECPTCGQFALLQATVQELTTHIHDLSLKLVGAEARISRLEQCDCQKSCYSNGTVHAD 213
L SECP G ++ A L + + + + LV +++ + + +
Sbjct: 201 L-SECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQI-LVELRDDIRDQVKEMSL 258
Query: 214 GATWQRDCNRCSCVHGEITCRPVECDR-AECKNPVLHPGECCPTCLRQCLLWGNLYEHGE 272
+C C C P C R +C +PG C C L GN +
Sbjct: 259 IRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPG--LQGNGTHCSD 316
Query: 273 RFAPKECAEC-VCHDGNMQCTRVDPELACPRLPCD-PPQQFSVPG-----ECCKFCPGVD 325
ECA C G+ C P C P Q S G + C +D
Sbjct: 317 ---INECAHADPCFPGS-SCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDID 372
Query: 326 YCNMGHS--CDENATCMNLNTKYTC-KCNQGFQGD-GLTCQDVDECQEAGGLHGHHCHSN 381
CN G++ CD N+ C N + C C GF G+ C C H CH +
Sbjct: 373 ECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPA--HS-PCHIH 429
Query: 382 TRCVNVVGGYV-CQCLGGY 399
C+ G V CQC G+
Sbjct: 430 AHCLFERNGAVSCQCNVGW 448
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 87.4 bits (207), Expect = 1e-16
Identities = 61/205 (29%), Positives = 84/205 (40%), Gaps = 23/205 (11%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA+ C N C + P C L ++P C+ ++ C
Sbjct: 848 CAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 339 CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLG 397
C++ Y C C GFQG CQD V+ C+ C + C+ GY+CQC
Sbjct: 907 CVDSGPSYFCHCPPGFQGS--LCQDHVNPCES------RPCQNGATCMAQPSGYLCQCAP 958
Query: 398 GYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECT 455
GY D NC E+D C+ CH CT PG + C C G+ G C VDEC
Sbjct: 959 GY---DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACPPGFV--GLRCEGDVDECL 1011
Query: 456 EGSHTCH--HSARCVNIDGGFRCEC 478
+ CH +A C ++ F C+C
Sbjct: 1012 D--QPCHPTGTAACHSLANAFYCQC 1034
Score = 80.6 bits (190), Expect = 2e-14
Identities = 75/276 (27%), Positives = 102/276 (36%), Gaps = 32/276 (11%)
Query: 221 CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECA 280
C+ C++G +C P C P H G C T C+ + G
Sbjct: 733 CHSGPCLNGG-SCNPSP-GGYYCTCPPSHTGPQCQTSTDYCVS-APCFNGGTCVNRPGTF 789
Query: 281 ECVCHDGNMQCTRVDPEL--ACPRLPCDPPQ--QFSVPGECCKFCPG----------VDY 326
C+C G Q R + +L +C PC Q S G C CP +D
Sbjct: 790 SCLCAMG-FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGGSCQTLMDL 847
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH----CHSNT 382
C C N+ C+ + C C QG+ G L + CQ+A G CH+
Sbjct: 848 CAQ-KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
CV+ Y C C G+ + V+ CE C A C P Y C+C GY+
Sbjct: 906 LCVDSGPSYFCHCPPGF--QGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYD 961
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + +D C S CH+ C GGF C C
Sbjct: 962 GQNCS-KELDACQ--SQPCHNHGTCTPKPGGFHCAC 994
Score = 78.2 bits (184), Expect = 9e-14
Identities = 84/292 (28%), Positives = 117/292 (40%), Gaps = 32/292 (10%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHP-GEC 253
EQC + C +N V+ +C C G E D EC ++P P G
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPG-FEGHACERDVNECFQDPGPCPKGTS 210
Query: 254 CPTCLR--QCLLWGNLYEHGERFAPKE--CAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C L QCL + + G R + C C +G C ++ PE C P
Sbjct: 211 CHNTLGSFQCLC--PVGQEGPRCELRAGPCPPRGCSNGGT-C-QLMPEKDSTFHLCLCPP 266
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
F P C+ P D C + H C TC + YTC C + + G + +DVDEC+
Sbjct: 267 GFIGPD--CEVNP--DNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS-EDVDECET 320
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTN 428
G HC + C N G + C C+ G+ +C E +D+C T C + C +
Sbjct: 321 QGP---PHCRNGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAAT--CAPGSTCID 372
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVN--IDGGFRCEC 478
GS++C C G G C D C S CH A+C + G C C
Sbjct: 373 RVGSFSCLCPPG--RTGLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLC 420
Score = 77.0 bits (181), Expect = 2e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 20/153 (13%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ C +TC++L + C C G +G C+ + +EC A L+ CH ++
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQ--LCEVETNECASAPCLNHADCH------DL 531
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ G+ C CL G++ C E +DEC + C C + PG++ C+C G+EG
Sbjct: 532 LNGFQCICLPGFSGT---RCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFEGP-- 584
Query: 447 TCM-HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C VDEC S C A C+++ G F C C
Sbjct: 585 RCQTEVDECL--SDPCPVGASCLDLPGAFFCLC 615
Score = 75.8 bits (178), Expect = 5e-13
Identities = 67/219 (30%), Positives = 87/219 (39%), Gaps = 36/219 (16%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP-GECCKFCPGVDYCN--------MGH 331
C C G D C PC + P G C+ PG D N
Sbjct: 916 CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ 975
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCH--SNTRCVNVV 388
C + TC + C C GF G L C+ DVDEC + CH C ++
Sbjct: 976 PCHNHGTCTPKPGGFHCACPPGFVG--LRCEGDVDECLD------QPCHPTGTAACHSLA 1027
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS---YTCRCRDGYEGDG 445
+ CQCL G+T ++ VE+D C ++ C C T GS + C C G+EG
Sbjct: 1028 NAFYCQCLPGHT--GQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGFEGP- 1082
Query: 446 YTCMH-VDECTEGSHTCHHSARCV-NIDGGF--RCECFT 480
TC H C G H CHH C+ + GF RC C +
Sbjct: 1083 -TCSHRAPSC--GFHHCHHGGLCLPSPKPGFPPRCACLS 1118
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + +C +TC++ ++C C G GL C D C CH + +
Sbjct: 356 LDDC-IAATCAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLS------QPCHGDAQ 406
Query: 384 CVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG---CHADAVCTNTPGSYTCRCR 438
C + G +C C GY+ ++DEC G C C NTPGS+ C C
Sbjct: 407 CSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 464
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY G H +EC S CH + C+++ F C C
Sbjct: 465 PGYTGSRCEADH-NECL--SQPCHPGSTCLDLLATFHCLC 501
Score = 68.5 bits (160), Expect = 7e-11
Identities = 54/212 (25%), Positives = 72/212 (33%), Gaps = 15/212 (7%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
K+ A C+C DG+ C + C C G C + C
Sbjct: 644 KDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 703
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC + Y C C G+ G TC + E H C + C GGY C C
Sbjct: 704 GTCYPQPSGYNCTCPTGYTGP--TCSE-----EMTACHSGPCLNGGSCNPSPGGYYCTCP 756
Query: 397 GGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
+T C D C C C N PG+++C C G++G C
Sbjct: 757 PSHTGPQ---CQTSTDYCVSAP--CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
Query: 456 EGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+ C + A C + G RC C T SC
Sbjct: 812 DS--PCRNRATCQDSPQGPRCLCPTGYTGGSC 841
Score = 65.7 bits (153), Expect = 5e-10
Identities = 69/246 (28%), Positives = 87/246 (35%), Gaps = 35/246 (14%)
Query: 224 CSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPKECAE 281
C C G R E D EC + HPG C L CL L ECA
Sbjct: 461 CLCPPGYTGSR-CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECAS 519
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMN 341
C + + C + C LP FS G C+ +D C C C +
Sbjct: 520 APCLN-HADCHDLLNGFQCICLP-----GFS--GTRCE--EDIDECRSS-PCANGGQCQD 568
Query: 342 LNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ CKC GF+G CQ +VDEC C C+++ G + C C G+T
Sbjct: 569 QPGAFHCKCLPGFEGP--RCQTEVDECLS------DPCPVGASCLDLPGAFFCLCPSGFT 620
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG-----DGYTCMHVDECT 455
+ EV C N C +C + C C DG G D TC H C
Sbjct: 621 GQ----LCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH-GHCQ 673
Query: 456 EGSHTC 461
S C
Sbjct: 674 RSSCVC 679
Score = 65.3 bits (152), Expect = 6e-10
Identities = 81/321 (25%), Positives = 112/321 (34%), Gaps = 67/321 (20%)
Query: 218 QRDCNRCSCVHGEITCRPVE---------CDRAECKNPVLHPGECCPTCLRQCLLWGNLY 268
Q+D C C G C P E C R+ C V G C L C+
Sbjct: 643 QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCI--SAPC 700
Query: 269 EHGERFAPKECA-ECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCP---- 322
HG P+ C C G T + AC PC + PG CP
Sbjct: 701 AHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
Query: 323 ------GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-----------------DGL 359
DYC + C TC+N ++C C GFQG +
Sbjct: 761 GPQCQTSTDYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 360 TCQDVDE---CQEAGGLHGHHCHS------------NTRCVNVVGGYVCQCLGGYT---- 400
TCQD + C G G C + N+ C+ + C CL G+T
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 401 RKDKFNCVEVDECEG--NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECTEG 457
+C + +G + CH +C ++ SY C C G++G C HV+ C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS--LCQDHVNPCE-- 935
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S C + A C+ G+ C+C
Sbjct: 936 SRPCQNGATCMAQPSGYLCQC 956
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 23/172 (13%)
Query: 333 CDENATCMNL----NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
C TC + +T + C C GF G C+ + D C H C + C +
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPD--CEVNPDNCVS------HQCQNGGTCQDG 294
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECE--GNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+ Y C C +T D C E VDECE G H C C N+ GS+ C C G+ G
Sbjct: 295 LDTYTCLCPETWTGWD---CSEDVDECETQGPPH-CRNGGTCQNSAGSFHCVCVSGWGGT 350
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
++D+C TC + C++ G F C C L C + +S+
Sbjct: 351 SCE-ENLDDCIAA--TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ 399
Score = 61.7 bits (143), Expect = 8e-09
Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 26/177 (14%)
Query: 315 GECCKF---CPGVDYCNMGHSCDE--------NATCMNLNTKYTCKCNQGFQGDGLTCQD 363
GE C+F C C G SC ++ L + C C GF G+ +
Sbjct: 59 GETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL 118
Query: 364 VDECQEAGGLHGHHCHSNTRC-VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
D C + C RC + G C C+ G+T + C D C N C
Sbjct: 119 EDPCPPS------FCSKRGRCHIQASGRPQCSCMPGWTGE---QCQLRDFCSANP--CVN 167
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC T C C G+E G+ C V+EC + C C N G F+C C
Sbjct: 168 GGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/262 (25%), Positives = 100/262 (38%), Gaps = 29/262 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPV--ECDRAEC- 243
G + LE + C+ + + T C C + TC EC A+
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLC-LCQPGYSGPTCHQDLDECLMAQQG 442
Query: 244 KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAP-KECAECVCHDGNMQCTRVDPELACPR 302
+P H G C T L Y A EC CH G+ C + LA
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDL---LATFH 498
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
C P + G+ C+ + C C +A C +L + C C GF G +
Sbjct: 499 CLCPP----GLEGQLCEV--ETNECASA-PCLNHADCHDLLNGFQCICLPGFSGTRCE-E 550
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCH 421
D+DEC+ + C + +C + G + C+CL G+ C EVDEC + C
Sbjct: 551 DIDECRSSP------CANGGQCQDQPGAFHCKCLPGFEGP---RCQTEVDECLSDP--CP 599
Query: 422 ADAVCTNTPGSYTCRCRDGYEG 443
A C + PG++ C C G+ G
Sbjct: 600 VGASCLDLPGAFFCLCPSGFTG 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 16/190 (8%)
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT 360
P++ C P F G C+ + + G C + +C N + C C G +G
Sbjct: 176 PQIQCHCPPGFE--GHACERDVNECFQDPG-PCPKGTSCHNTLGSFQCLCPVGQEGPRCE 232
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHG 419
+ C G +G C + ++C C G+ D C V D C +H
Sbjct: 233 LR-AGPCPPRGCSNGGTCQLMPEKDSTF--HLCLCPPGFIGPD---CEVNPDNCV--SHQ 284
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDEC-TEGSHTCHHSARCVNIDGGFRCE 477
C C + +YTC C + + G + C VDEC T+G C + C N G F C
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTG--WDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 478 CFTENCELSC 487
C + SC
Sbjct: 343 CVSGWGGTSC 352
Score = 39.1 bits (87), Expect = 0.048
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 333 CDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C + C + + + C C G+ G+ CQ D C + C + C+
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCS------ANPCVNGGVCLATYPQI 178
Query: 392 VCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C G+ + C +V+EC + C C NT GS+ C C G EG
Sbjct: 179 QCHCPPGF---EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 87.4 bits (207), Expect = 1e-16
Identities = 61/205 (29%), Positives = 84/205 (40%), Gaps = 23/205 (11%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA+ C N C + P C L ++P C+ ++ C
Sbjct: 847 CAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 905
Query: 339 CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLG 397
C++ Y C C GFQG CQD V+ C+ C + C+ GY+CQC
Sbjct: 906 CVDSGPSYFCHCPPGFQGS--LCQDHVNPCES------RPCQNGATCMAQPSGYLCQCAP 957
Query: 398 GYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECT 455
GY D NC E+D C+ CH CT PG + C C G+ G C VDEC
Sbjct: 958 GY---DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACPPGFV--GLRCEGDVDECL 1010
Query: 456 EGSHTCH--HSARCVNIDGGFRCEC 478
+ CH +A C ++ F C+C
Sbjct: 1011 D--QPCHPTGTAACHSLANAFYCQC 1033
Score = 81.0 bits (191), Expect = 1e-14
Identities = 85/292 (29%), Positives = 118/292 (40%), Gaps = 32/292 (10%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHP-GEC 253
EQC + C +N V+ +C C G E D EC ++P P G
Sbjct: 151 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPG-FEGHACERDVNECFQDPGPCPKGTS 209
Query: 254 CPTCLR--QCLLWGNLYEHGERFAPKE--CAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C L QCL + + G R + C C +G C ++ PE C P
Sbjct: 210 CHNTLGSFQCLC--PVGQEGPRCELRAGPCPPRGCSNGGT-C-QLMPEKDSTFHLCLCPP 265
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
F PG C+ P D C + H C TC + YTC C + + G + +DVDEC+
Sbjct: 266 GFIGPG--CEVNP--DNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS-EDVDECEA 319
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTN 428
G HC + C N G + C C+ G+ +C E +D+C T C + C +
Sbjct: 320 QGP---PHCRNGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAAT--CAPGSTCID 371
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVN--IDGGFRCEC 478
GS++C C G G C D C S CH A+C + G C C
Sbjct: 372 RVGSFSCLCPPG--RTGLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLC 419
Score = 80.6 bits (190), Expect = 2e-14
Identities = 75/276 (27%), Positives = 102/276 (36%), Gaps = 32/276 (11%)
Query: 221 CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECA 280
C+ C++G +C P C P H G C T C+ + G
Sbjct: 732 CHSGPCLNGG-SCNPSP-GGYYCTCPPSHTGPQCQTSTDYCVS-APCFNGGTCVNRPGTF 788
Query: 281 ECVCHDGNMQCTRVDPEL--ACPRLPCDPPQ--QFSVPGECCKFCPG----------VDY 326
C+C G Q R + +L +C PC Q S G C CP +D
Sbjct: 789 SCLCAMG-FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGGSCQTLMDL 846
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH----CHSNT 382
C C N+ C+ + C C QG+ G L + CQ+A G CH+
Sbjct: 847 CAQ-KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLSSCQKAALSQGIDVSSLCHNGG 904
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
CV+ Y C C G+ + V+ CE C A C P Y C+C GY+
Sbjct: 905 LCVDSGPSYFCHCPPGF--QGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYD 960
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + +D C S CH+ C GGF C C
Sbjct: 961 GQNCS-KELDACQ--SQPCHNHGTCTPKPGGFHCAC 993
Score = 77.0 bits (181), Expect = 2e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 20/153 (13%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ C +TC++L + C C G +G C+ + +EC A L+ CH ++
Sbjct: 479 LSQPCHPGSTCLDLLATFHCLCPPGLEGQ--LCEVETNECASAPCLNHADCH------DL 530
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ G+ C CL G++ C E +DEC + C C + PG++ C+C G+EG
Sbjct: 531 LNGFQCICLPGFSGT---RCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFEGP-- 583
Query: 447 TCM-HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C VDEC S C A C+++ G F C C
Sbjct: 584 RCQTEVDECL--SDPCPVGASCLDLPGAFFCLC 614
Score = 75.8 bits (178), Expect = 5e-13
Identities = 67/219 (30%), Positives = 87/219 (39%), Gaps = 36/219 (16%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP-GECCKFCPGVDYCN--------MGH 331
C C G D C PC + P G C+ PG D N
Sbjct: 915 CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ 974
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCH--SNTRCVNVV 388
C + TC + C C GF G L C+ DVDEC + CH C ++
Sbjct: 975 PCHNHGTCTPKPGGFHCACPPGFVG--LRCEGDVDECLD------QPCHPTGTAACHSLA 1026
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS---YTCRCRDGYEGDG 445
+ CQCL G+T ++ VE+D C ++ C C T GS + C C G+EG
Sbjct: 1027 NAFYCQCLPGHT--GQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGFEGP- 1081
Query: 446 YTCMH-VDECTEGSHTCHHSARCV-NIDGGF--RCECFT 480
TC H C G H CHH C+ + GF RC C +
Sbjct: 1082 -TCSHRAPSC--GFHHCHHGGLCLPSPKPGFPPRCACLS 1117
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + +C +TC++ ++C C G GL C D C CH + +
Sbjct: 355 LDDC-IAATCAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLS------QPCHGDAQ 405
Query: 384 CVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG---CHADAVCTNTPGSYTCRCR 438
C + G +C C GY+ ++DEC G C C NTPGS+ C C
Sbjct: 406 CSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 463
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY G H +EC S CH + C+++ F C C
Sbjct: 464 PGYTGSRCEADH-NECL--SQPCHPGSTCLDLLATFHCLC 500
Score = 68.5 bits (160), Expect = 7e-11
Identities = 54/212 (25%), Positives = 72/212 (33%), Gaps = 15/212 (7%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
K+ A C+C DG+ C + C C G C + C
Sbjct: 643 KDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 702
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC + Y C C G+ G TC + E H C + C GGY C C
Sbjct: 703 GTCYPQPSGYNCTCPTGYTGP--TCSE-----EMTACHSGPCLNGGSCNPSPGGYYCTCP 755
Query: 397 GGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
+T C D C C C N PG+++C C G++G C
Sbjct: 756 PSHTGPQ---CQTSTDYCVSAP--CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 810
Query: 456 EGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+ C + A C + G RC C T SC
Sbjct: 811 DS--PCRNRATCQDSPQGPRCLCPTGYTGGSC 840
Score = 65.7 bits (153), Expect = 5e-10
Identities = 51/172 (29%), Positives = 72/172 (41%), Gaps = 23/172 (13%)
Query: 333 CDENATCMNL----NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
C TC + +T + C C GF G G C+ + D C H C + C +
Sbjct: 242 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPG--CEVNPDNCVS------HQCQNGGTCQDG 293
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECE--GNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+ Y C C +T D C E VDECE G H C C N+ GS+ C C G+ G
Sbjct: 294 LDTYTCLCPETWTGWD---CSEDVDECEAQGPPH-CRNGGTCQNSAGSFHCVCVSGWGGT 349
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
++D+C TC + C++ G F C C L C + +S+
Sbjct: 350 SCE-ENLDDCIAA--TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ 398
Score = 65.7 bits (153), Expect = 5e-10
Identities = 69/246 (28%), Positives = 87/246 (35%), Gaps = 35/246 (14%)
Query: 224 CSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPKECAE 281
C C G R E D EC + HPG C L CL L ECA
Sbjct: 460 CLCPPGYTGSR-CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECAS 518
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMN 341
C + + C + C LP FS G C+ +D C C C +
Sbjct: 519 APCLN-HADCHDLLNGFQCICLP-----GFS--GTRCE--EDIDECRSS-PCANGGQCQD 567
Query: 342 LNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ CKC GF+G CQ +VDEC C C+++ G + C C G+T
Sbjct: 568 QPGAFHCKCLPGFEGP--RCQTEVDECLS------DPCPVGASCLDLPGAFFCLCPSGFT 619
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG-----DGYTCMHVDECT 455
+ EV C N C +C + C C DG G D TC H C
Sbjct: 620 GQ----LCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH-GHCQ 672
Query: 456 EGSHTC 461
S C
Sbjct: 673 RSSCVC 678
Score = 65.3 bits (152), Expect = 6e-10
Identities = 81/321 (25%), Positives = 112/321 (34%), Gaps = 67/321 (20%)
Query: 218 QRDCNRCSCVHGEITCRPVE---------CDRAECKNPVLHPGECCPTCLRQCLLWGNLY 268
Q+D C C G C P E C R+ C V G C L C+
Sbjct: 642 QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCI--SAPC 699
Query: 269 EHGERFAPKECA-ECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCP---- 322
HG P+ C C G T + AC PC + PG CP
Sbjct: 700 AHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 759
Query: 323 ------GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-----------------DGL 359
DYC + C TC+N ++C C GFQG +
Sbjct: 760 GPQCQTSTDYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 818
Query: 360 TCQDVDE---CQEAGGLHGHHCHS------------NTRCVNVVGGYVCQCLGGYT---- 400
TCQD + C G G C + N+ C+ + C CL G+T
Sbjct: 819 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 878
Query: 401 RKDKFNCVEVDECEG--NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECTEG 457
+C + +G + CH +C ++ SY C C G++G C HV+ C
Sbjct: 879 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS--LCQDHVNPCE-- 934
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S C + A C+ G+ C+C
Sbjct: 935 SRPCQNGATCMAQPSGYLCQC 955
Score = 61.7 bits (143), Expect = 8e-09
Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 26/177 (14%)
Query: 315 GECCKF---CPGVDYCNMGHSCDE--------NATCMNLNTKYTCKCNQGFQGDGLTCQD 363
GE C+F C C G SC ++ L + C C GF G+ +
Sbjct: 58 GETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL 117
Query: 364 VDECQEAGGLHGHHCHSNTRC-VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
D C + C RC + G C C+ G+T + C D C N C
Sbjct: 118 EDPCPPS------FCSKRGRCHIQASGRPQCSCMPGWTGE---QCQLRDFCSANP--CVN 166
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC T C C G+E G+ C V+EC + C C N G F+C C
Sbjct: 167 GGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 221
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/262 (25%), Positives = 100/262 (38%), Gaps = 29/262 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPV--ECDRAEC- 243
G + LE + C+ + + T C C + TC EC A+
Sbjct: 383 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLC-LCQPGYSGPTCHQDLDECLMAQQG 441
Query: 244 KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAP-KECAECVCHDGNMQCTRVDPELACPR 302
+P H G C T L Y A EC CH G+ C + LA
Sbjct: 442 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDL---LATFH 497
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
C P + G+ C+ + C C +A C +L + C C GF G +
Sbjct: 498 CLCPP----GLEGQLCEV--ETNECASA-PCLNHADCHDLLNGFQCICLPGFSGTRCE-E 549
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCH 421
D+DEC+ + C + +C + G + C+CL G+ C EVDEC + C
Sbjct: 550 DIDECRSSP------CANGGQCQDQPGAFHCKCLPGFEGP---RCQTEVDECLSDP--CP 598
Query: 422 ADAVCTNTPGSYTCRCRDGYEG 443
A C + PG++ C C G+ G
Sbjct: 599 VGASCLDLPGAFFCLCPSGFTG 620
Score = 55.6 bits (128), Expect = 5e-07
Identities = 48/190 (25%), Positives = 72/190 (37%), Gaps = 16/190 (8%)
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT 360
P++ C P F G C+ + + G C + +C N + C C G +G
Sbjct: 175 PQIQCHCPPGFE--GHACERDVNECFQDPG-PCPKGTSCHNTLGSFQCLCPVGQEGPRCE 231
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHG 419
+ C G +G C + ++C C G+ C V D C +H
Sbjct: 232 LR-AGPCPPRGCSNGGTCQLMPEKDSTF--HLCLCPPGFIGP---GCEVNPDNCV--SHQ 283
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDEC-TEGSHTCHHSARCVNIDGGFRCE 477
C C + +YTC C + + G + C VDEC +G C + C N G F C
Sbjct: 284 CQNGGTCQDGLDTYTCLCPETWTG--WDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCV 341
Query: 478 CFTENCELSC 487
C + SC
Sbjct: 342 CVSGWGGTSC 351
Score = 39.1 bits (87), Expect = 0.048
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 333 CDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C + C + + + C C G+ G+ CQ D C + C + C+
Sbjct: 126 CSKRGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCS------ANPCVNGGVCLATYPQI 177
Query: 392 VCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C G+ + C +V+EC + C C NT GS+ C C G EG
Sbjct: 178 QCHCPPGF---EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEG 227
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 87.4 bits (207), Expect = 1e-16
Identities = 61/205 (29%), Positives = 84/205 (40%), Gaps = 23/205 (11%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA+ C N C + P C L ++P C+ ++ C
Sbjct: 848 CAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 339 CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLG 397
C++ Y C C GFQG CQD V+ C+ C + C+ GY+CQC
Sbjct: 907 CVDSGPSYFCHCPPGFQGS--LCQDHVNPCES------RPCQNGATCMAQPSGYLCQCAP 958
Query: 398 GYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECT 455
GY D NC E+D C+ CH CT PG + C C G+ G C VDEC
Sbjct: 959 GY---DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACPPGFV--GLRCEGDVDECL 1011
Query: 456 EGSHTCH--HSARCVNIDGGFRCEC 478
+ CH +A C ++ F C+C
Sbjct: 1012 D--QPCHPTGTAACHSLANAFYCQC 1034
Score = 80.6 bits (190), Expect = 2e-14
Identities = 75/276 (27%), Positives = 102/276 (36%), Gaps = 32/276 (11%)
Query: 221 CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECA 280
C+ C++G +C P C P H G C T C+ + G
Sbjct: 733 CHSGPCLNGG-SCNPSP-GGYYCTCPPSHTGPQCQTSTDYCVS-APCFNGGTCVNRPGTF 789
Query: 281 ECVCHDGNMQCTRVDPEL--ACPRLPCDPPQ--QFSVPGECCKFCPG----------VDY 326
C+C G Q R + +L +C PC Q S G C CP +D
Sbjct: 790 SCLCAMG-FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGGSCQTLMDL 847
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH----CHSNT 382
C C N+ C+ + C C QG+ G L + CQ+A G CH+
Sbjct: 848 CAQ-KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
CV+ Y C C G+ + V+ CE C A C P Y C+C GY+
Sbjct: 906 LCVDSGPSYFCHCPPGF--QGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYD 961
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + +D C S CH+ C GGF C C
Sbjct: 962 GQNCS-KELDACQ--SQPCHNHGTCTPKPGGFHCAC 994
Score = 78.2 bits (184), Expect = 9e-14
Identities = 84/292 (28%), Positives = 117/292 (40%), Gaps = 32/292 (10%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHP-GEC 253
EQC + C +N V+ +C C G E D EC ++P P G
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPG-FEGHACERDVNECFQDPGPCPKGTS 210
Query: 254 CPTCLR--QCLLWGNLYEHGERFAPKE--CAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C L QCL + + G R + C C +G C ++ PE C P
Sbjct: 211 CHNTLGSFQCLC--PVGQEGPRCELRAGPCPPRGCSNGGT-C-QLMPEKDSTFHLCLCPP 266
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
F P C+ P D C + H C TC + YTC C + + G + +DVDEC+
Sbjct: 267 GFIGPD--CEVNP--DNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS-EDVDECET 320
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTN 428
G HC + C N G + C C+ G+ +C E +D+C T C + C +
Sbjct: 321 QGP---PHCRNGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAAT--CAPGSTCID 372
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVN--IDGGFRCEC 478
GS++C C G G C D C S CH A+C + G C C
Sbjct: 373 RVGSFSCLCPPG--RTGLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLC 420
Score = 77.0 bits (181), Expect = 2e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 20/153 (13%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ C +TC++L + C C G +G C+ + +EC A L+ CH ++
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQ--LCEVETNECASAPCLNHADCH------DL 531
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ G+ C CL G++ C E +DEC + C C + PG++ C+C G+EG
Sbjct: 532 LNGFQCICLPGFSGT---RCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFEGP-- 584
Query: 447 TCM-HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C VDEC S C A C+++ G F C C
Sbjct: 585 RCQTEVDECL--SDPCPVGASCLDLPGAFFCLC 615
Score = 75.8 bits (178), Expect = 5e-13
Identities = 67/219 (30%), Positives = 87/219 (39%), Gaps = 36/219 (16%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP-GECCKFCPGVDYCN--------MGH 331
C C G D C PC + P G C+ PG D N
Sbjct: 916 CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ 975
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCH--SNTRCVNVV 388
C + TC + C C GF G L C+ DVDEC + CH C ++
Sbjct: 976 PCHNHGTCTPKPGGFHCACPPGFVG--LRCEGDVDECLD------QPCHPTGTAACHSLA 1027
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS---YTCRCRDGYEGDG 445
+ CQCL G+T ++ VE+D C ++ C C T GS + C C G+EG
Sbjct: 1028 NAFYCQCLPGHT--GQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGFEGP- 1082
Query: 446 YTCMH-VDECTEGSHTCHHSARCV-NIDGGF--RCECFT 480
TC H C G H CHH C+ + GF RC C +
Sbjct: 1083 -TCSHRAPSC--GFHHCHHGGLCLPSPKPGFPPRCACLS 1118
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + +C +TC++ ++C C G GL C D C CH + +
Sbjct: 356 LDDC-IAATCAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLS------QPCHGDAQ 406
Query: 384 CVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG---CHADAVCTNTPGSYTCRCR 438
C + G +C C GY+ ++DEC G C C NTPGS+ C C
Sbjct: 407 CSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 464
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY G H +EC S CH + C+++ F C C
Sbjct: 465 PGYTGSRCEADH-NECL--SQPCHPGSTCLDLLATFHCLC 501
Score = 68.5 bits (160), Expect = 7e-11
Identities = 54/212 (25%), Positives = 72/212 (33%), Gaps = 15/212 (7%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
K+ A C+C DG+ C + C C G C + C
Sbjct: 644 KDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 703
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC + Y C C G+ G TC + E H C + C GGY C C
Sbjct: 704 GTCYPQPSGYNCTCPTGYTGP--TCSE-----EMTACHSGPCLNGGSCNPSPGGYYCTCP 756
Query: 397 GGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
+T C D C C C N PG+++C C G++G C
Sbjct: 757 PSHTGPQ---CQTSTDYCVSAP--CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
Query: 456 EGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+ C + A C + G RC C T SC
Sbjct: 812 DS--PCRNRATCQDSPQGPRCLCPTGYTGGSC 841
Score = 65.7 bits (153), Expect = 5e-10
Identities = 69/246 (28%), Positives = 87/246 (35%), Gaps = 35/246 (14%)
Query: 224 CSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPKECAE 281
C C G R E D EC + HPG C L CL L ECA
Sbjct: 461 CLCPPGYTGSR-CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECAS 519
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMN 341
C + + C + C LP FS G C+ +D C C C +
Sbjct: 520 APCLN-HADCHDLLNGFQCICLP-----GFS--GTRCE--EDIDECRSS-PCANGGQCQD 568
Query: 342 LNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ CKC GF+G CQ +VDEC C C+++ G + C C G+T
Sbjct: 569 QPGAFHCKCLPGFEGP--RCQTEVDECLS------DPCPVGASCLDLPGAFFCLCPSGFT 620
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG-----DGYTCMHVDECT 455
+ EV C N C +C + C C DG G D TC H C
Sbjct: 621 GQ----LCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH-GHCQ 673
Query: 456 EGSHTC 461
S C
Sbjct: 674 RSSCVC 679
Score = 65.3 bits (152), Expect = 6e-10
Identities = 81/321 (25%), Positives = 112/321 (34%), Gaps = 67/321 (20%)
Query: 218 QRDCNRCSCVHGEITCRPVE---------CDRAECKNPVLHPGECCPTCLRQCLLWGNLY 268
Q+D C C G C P E C R+ C V G C L C+
Sbjct: 643 QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCI--SAPC 700
Query: 269 EHGERFAPKECA-ECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCP---- 322
HG P+ C C G T + AC PC + PG CP
Sbjct: 701 AHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
Query: 323 ------GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-----------------DGL 359
DYC + C TC+N ++C C GFQG +
Sbjct: 761 GPQCQTSTDYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 360 TCQDVDE---CQEAGGLHGHHCHS------------NTRCVNVVGGYVCQCLGGYT---- 400
TCQD + C G G C + N+ C+ + C CL G+T
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 401 RKDKFNCVEVDECEG--NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECTEG 457
+C + +G + CH +C ++ SY C C G++G C HV+ C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS--LCQDHVNPCE-- 935
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S C + A C+ G+ C+C
Sbjct: 936 SRPCQNGATCMAQPSGYLCQC 956
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 23/172 (13%)
Query: 333 CDENATCMNL----NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
C TC + +T + C C GF G C+ + D C H C + C +
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPD--CEVNPDNCVS------HQCQNGGTCQDG 294
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECE--GNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+ Y C C +T D C E VDECE G H C C N+ GS+ C C G+ G
Sbjct: 295 LDTYTCLCPETWTGWD---CSEDVDECETQGPPH-CRNGGTCQNSAGSFHCVCVSGWGGT 350
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
++D+C TC + C++ G F C C L C + +S+
Sbjct: 351 SCE-ENLDDCIAA--TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ 399
Score = 61.7 bits (143), Expect = 8e-09
Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 26/177 (14%)
Query: 315 GECCKF---CPGVDYCNMGHSCDE--------NATCMNLNTKYTCKCNQGFQGDGLTCQD 363
GE C+F C C G SC ++ L + C C GF G+ +
Sbjct: 59 GETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL 118
Query: 364 VDECQEAGGLHGHHCHSNTRC-VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
D C + C RC + G C C+ G+T + C D C N C
Sbjct: 119 EDPCPPS------FCSKRGRCHIQASGRPQCSCMPGWTGE---QCQLRDFCSANP--CVN 167
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC T C C G+E G+ C V+EC + C C N G F+C C
Sbjct: 168 GGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/262 (25%), Positives = 100/262 (38%), Gaps = 29/262 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPV--ECDRAEC- 243
G + LE + C+ + + T C C + TC EC A+
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLC-LCQPGYSGPTCHQDLDECLMAQQG 442
Query: 244 KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAP-KECAECVCHDGNMQCTRVDPELACPR 302
+P H G C T L Y A EC CH G+ C + LA
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDL---LATFH 498
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
C P + G+ C+ + C C +A C +L + C C GF G +
Sbjct: 499 CLCPP----GLEGQLCEV--ETNECASA-PCLNHADCHDLLNGFQCICLPGFSGTRCE-E 550
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCH 421
D+DEC+ + C + +C + G + C+CL G+ C EVDEC + C
Sbjct: 551 DIDECRSSP------CANGGQCQDQPGAFHCKCLPGFEGP---RCQTEVDECLSDP--CP 599
Query: 422 ADAVCTNTPGSYTCRCRDGYEG 443
A C + PG++ C C G+ G
Sbjct: 600 VGASCLDLPGAFFCLCPSGFTG 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 16/190 (8%)
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT 360
P++ C P F G C+ + + G C + +C N + C C G +G
Sbjct: 176 PQIQCHCPPGFE--GHACERDVNECFQDPG-PCPKGTSCHNTLGSFQCLCPVGQEGPRCE 232
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHG 419
+ C G +G C + ++C C G+ D C V D C +H
Sbjct: 233 LR-AGPCPPRGCSNGGTCQLMPEKDSTF--HLCLCPPGFIGPD---CEVNPDNCV--SHQ 284
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDEC-TEGSHTCHHSARCVNIDGGFRCE 477
C C + +YTC C + + G + C VDEC T+G C + C N G F C
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTG--WDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 478 CFTENCELSC 487
C + SC
Sbjct: 343 CVSGWGGTSC 352
Score = 39.1 bits (87), Expect = 0.048
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 333 CDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C + C + + + C C G+ G+ CQ D C + C + C+
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCS------ANPCVNGGVCLATYPQI 178
Query: 392 VCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C G+ + C +V+EC + C C NT GS+ C C G EG
Sbjct: 179 QCHCPPGF---EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 87.4 bits (207), Expect = 1e-16
Identities = 61/205 (29%), Positives = 84/205 (40%), Gaps = 23/205 (11%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA+ C N C + P C L ++P C+ ++ C
Sbjct: 848 CAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 339 CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLG 397
C++ Y C C GFQG CQD V+ C+ C + C+ GY+CQC
Sbjct: 907 CVDSGPSYFCHCPPGFQGS--LCQDHVNPCES------RPCQNGATCMAQPSGYLCQCAP 958
Query: 398 GYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECT 455
GY D NC E+D C+ CH CT PG + C C G+ G C VDEC
Sbjct: 959 GY---DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACPPGFV--GLRCEGDVDECL 1011
Query: 456 EGSHTCH--HSARCVNIDGGFRCEC 478
+ CH +A C ++ F C+C
Sbjct: 1012 D--QPCHPTGTAACHSLANAFYCQC 1034
Score = 80.6 bits (190), Expect = 2e-14
Identities = 75/276 (27%), Positives = 102/276 (36%), Gaps = 32/276 (11%)
Query: 221 CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECA 280
C+ C++G +C P C P H G C T C+ + G
Sbjct: 733 CHSGPCLNGG-SCNPSP-GGYYCTCPPSHTGPQCQTSTDYCVS-APCFNGGTCVNRPGTF 789
Query: 281 ECVCHDGNMQCTRVDPEL--ACPRLPCDPPQ--QFSVPGECCKFCPG----------VDY 326
C+C G Q R + +L +C PC Q S G C CP +D
Sbjct: 790 SCLCAMG-FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGGSCQTLMDL 847
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH----CHSNT 382
C C N+ C+ + C C QG+ G L + CQ+A G CH+
Sbjct: 848 CAQ-KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
CV+ Y C C G+ + V+ CE C A C P Y C+C GY+
Sbjct: 906 LCVDSGPSYFCHCPPGF--QGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYD 961
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + +D C S CH+ C GGF C C
Sbjct: 962 GQNCS-KELDACQ--SQPCHNHGTCTPKPGGFHCAC 994
Score = 78.2 bits (184), Expect = 9e-14
Identities = 84/292 (28%), Positives = 117/292 (40%), Gaps = 32/292 (10%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHP-GEC 253
EQC + C +N V+ +C C G E D EC ++P P G
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPG-FEGHACERDVNECFQDPGPCPKGTS 210
Query: 254 CPTCLR--QCLLWGNLYEHGERFAPKE--CAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C L QCL + + G R + C C +G C ++ PE C P
Sbjct: 211 CHNTLGSFQCLC--PVGQEGPRCELRAGPCPPRGCSNGGT-C-QLMPEKDSTFHLCLCPP 266
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
F P C+ P D C + H C TC + YTC C + + G + +DVDEC+
Sbjct: 267 GFIGPD--CEVNP--DNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS-EDVDECET 320
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTN 428
G HC + C N G + C C+ G+ +C E +D+C T C + C +
Sbjct: 321 QGP---PHCRNGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAAT--CAPGSTCID 372
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVN--IDGGFRCEC 478
GS++C C G G C D C S CH A+C + G C C
Sbjct: 373 RVGSFSCLCPPG--RTGLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLC 420
Score = 77.0 bits (181), Expect = 2e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 20/153 (13%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ C +TC++L + C C G +G C+ + +EC A L+ CH ++
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQ--LCEVETNECASAPCLNHADCH------DL 531
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ G+ C CL G++ C E +DEC + C C + PG++ C+C G+EG
Sbjct: 532 LNGFQCICLPGFSGT---RCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFEGP-- 584
Query: 447 TCM-HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C VDEC S C A C+++ G F C C
Sbjct: 585 RCQTEVDECL--SDPCPVGASCLDLPGAFFCLC 615
Score = 75.8 bits (178), Expect = 5e-13
Identities = 67/219 (30%), Positives = 87/219 (39%), Gaps = 36/219 (16%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP-GECCKFCPGVDYCN--------MGH 331
C C G D C PC + P G C+ PG D N
Sbjct: 916 CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ 975
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCH--SNTRCVNVV 388
C + TC + C C GF G L C+ DVDEC + CH C ++
Sbjct: 976 PCHNHGTCTPKPGGFHCACPPGFVG--LRCEGDVDECLD------QPCHPTGTAACHSLA 1027
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS---YTCRCRDGYEGDG 445
+ CQCL G+T ++ VE+D C ++ C C T GS + C C G+EG
Sbjct: 1028 NAFYCQCLPGHT--GQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGFEGP- 1082
Query: 446 YTCMH-VDECTEGSHTCHHSARCV-NIDGGF--RCECFT 480
TC H C G H CHH C+ + GF RC C +
Sbjct: 1083 -TCSHRAPSC--GFHHCHHGGLCLPSPKPGFPPRCACLS 1118
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + +C +TC++ ++C C G GL C D C CH + +
Sbjct: 356 LDDC-IAATCAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLS------QPCHGDAQ 406
Query: 384 CVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG---CHADAVCTNTPGSYTCRCR 438
C + G +C C GY+ ++DEC G C C NTPGS+ C C
Sbjct: 407 CSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 464
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY G H +EC S CH + C+++ F C C
Sbjct: 465 PGYTGSRCEADH-NECL--SQPCHPGSTCLDLLATFHCLC 501
Score = 68.5 bits (160), Expect = 7e-11
Identities = 54/212 (25%), Positives = 72/212 (33%), Gaps = 15/212 (7%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
K+ A C+C DG+ C + C C G C + C
Sbjct: 644 KDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 703
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC + Y C C G+ G TC + E H C + C GGY C C
Sbjct: 704 GTCYPQPSGYNCTCPTGYTGP--TCSE-----EMTACHSGPCLNGGSCNPSPGGYYCTCP 756
Query: 397 GGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
+T C D C C C N PG+++C C G++G C
Sbjct: 757 PSHTGPQ---CQTSTDYCVSAP--CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
Query: 456 EGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+ C + A C + G RC C T SC
Sbjct: 812 DS--PCRNRATCQDSPQGPRCLCPTGYTGGSC 841
Score = 65.7 bits (153), Expect = 5e-10
Identities = 69/246 (28%), Positives = 87/246 (35%), Gaps = 35/246 (14%)
Query: 224 CSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPKECAE 281
C C G R E D EC + HPG C L CL L ECA
Sbjct: 461 CLCPPGYTGSR-CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECAS 519
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMN 341
C + + C + C LP FS G C+ +D C C C +
Sbjct: 520 APCLN-HADCHDLLNGFQCICLP-----GFS--GTRCE--EDIDECRSS-PCANGGQCQD 568
Query: 342 LNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ CKC GF+G CQ +VDEC C C+++ G + C C G+T
Sbjct: 569 QPGAFHCKCLPGFEGP--RCQTEVDECLS------DPCPVGASCLDLPGAFFCLCPSGFT 620
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG-----DGYTCMHVDECT 455
+ EV C N C +C + C C DG G D TC H C
Sbjct: 621 GQ----LCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH-GHCQ 673
Query: 456 EGSHTC 461
S C
Sbjct: 674 RSSCVC 679
Score = 65.3 bits (152), Expect = 6e-10
Identities = 81/321 (25%), Positives = 112/321 (34%), Gaps = 67/321 (20%)
Query: 218 QRDCNRCSCVHGEITCRPVE---------CDRAECKNPVLHPGECCPTCLRQCLLWGNLY 268
Q+D C C G C P E C R+ C V G C L C+
Sbjct: 643 QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCI--SAPC 700
Query: 269 EHGERFAPKECA-ECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCP---- 322
HG P+ C C G T + AC PC + PG CP
Sbjct: 701 AHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
Query: 323 ------GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-----------------DGL 359
DYC + C TC+N ++C C GFQG +
Sbjct: 761 GPQCQTSTDYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 360 TCQDVDE---CQEAGGLHGHHCHS------------NTRCVNVVGGYVCQCLGGYT---- 400
TCQD + C G G C + N+ C+ + C CL G+T
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 401 RKDKFNCVEVDECEG--NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECTEG 457
+C + +G + CH +C ++ SY C C G++G C HV+ C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS--LCQDHVNPCE-- 935
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S C + A C+ G+ C+C
Sbjct: 936 SRPCQNGATCMAQPSGYLCQC 956
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 23/172 (13%)
Query: 333 CDENATCMNL----NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
C TC + +T + C C GF G C+ + D C H C + C +
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPD--CEVNPDNCVS------HQCQNGGTCQDG 294
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECE--GNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+ Y C C +T D C E VDECE G H C C N+ GS+ C C G+ G
Sbjct: 295 LDTYTCLCPETWTGWD---CSEDVDECETQGPPH-CRNGGTCQNSAGSFHCVCVSGWGGT 350
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
++D+C TC + C++ G F C C L C + +S+
Sbjct: 351 SCE-ENLDDCIAA--TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ 399
Score = 61.7 bits (143), Expect = 8e-09
Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 26/177 (14%)
Query: 315 GECCKF---CPGVDYCNMGHSCDE--------NATCMNLNTKYTCKCNQGFQGDGLTCQD 363
GE C+F C C G SC ++ L + C C GF G+ +
Sbjct: 59 GETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL 118
Query: 364 VDECQEAGGLHGHHCHSNTRC-VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
D C + C RC + G C C+ G+T + C D C N C
Sbjct: 119 EDPCPPS------FCSKRGRCHIQASGRPQCSCMPGWTGE---QCQLRDFCSANP--CVN 167
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC T C C G+E G+ C V+EC + C C N G F+C C
Sbjct: 168 GGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/262 (25%), Positives = 100/262 (38%), Gaps = 29/262 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPV--ECDRAEC- 243
G + LE + C+ + + T C C + TC EC A+
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLC-LCQPGYSGPTCHQDLDECLMAQQG 442
Query: 244 KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAP-KECAECVCHDGNMQCTRVDPELACPR 302
+P H G C T L Y A EC CH G+ C + LA
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDL---LATFH 498
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
C P + G+ C+ + C C +A C +L + C C GF G +
Sbjct: 499 CLCPP----GLEGQLCEV--ETNECASA-PCLNHADCHDLLNGFQCICLPGFSGTRCE-E 550
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCH 421
D+DEC+ + C + +C + G + C+CL G+ C EVDEC + C
Sbjct: 551 DIDECRSSP------CANGGQCQDQPGAFHCKCLPGFEGP---RCQTEVDECLSDP--CP 599
Query: 422 ADAVCTNTPGSYTCRCRDGYEG 443
A C + PG++ C C G+ G
Sbjct: 600 VGASCLDLPGAFFCLCPSGFTG 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 16/190 (8%)
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT 360
P++ C P F G C+ + + G C + +C N + C C G +G
Sbjct: 176 PQIQCHCPPGFE--GHACERDVNECFQDPG-PCPKGTSCHNTLGSFQCLCPVGQEGPRCE 232
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHG 419
+ C G +G C + ++C C G+ D C V D C +H
Sbjct: 233 LR-AGPCPPRGCSNGGTCQLMPEKDSTF--HLCLCPPGFIGPD---CEVNPDNCV--SHQ 284
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDEC-TEGSHTCHHSARCVNIDGGFRCE 477
C C + +YTC C + + G + C VDEC T+G C + C N G F C
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTG--WDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 478 CFTENCELSC 487
C + SC
Sbjct: 343 CVSGWGGTSC 352
Score = 39.1 bits (87), Expect = 0.048
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 333 CDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C + C + + + C C G+ G+ CQ D C + C + C+
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCS------ANPCVNGGVCLATYPQI 178
Query: 392 VCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C G+ + C +V+EC + C C NT GS+ C C G EG
Sbjct: 179 QCHCPPGF---EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 87.4 bits (207), Expect = 1e-16
Identities = 61/205 (29%), Positives = 84/205 (40%), Gaps = 23/205 (11%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA+ C N C + P C L ++P C+ ++ C
Sbjct: 848 CAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 339 CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLG 397
C++ Y C C GFQG CQD V+ C+ C + C+ GY+CQC
Sbjct: 907 CVDSGPSYFCHCPPGFQGS--LCQDHVNPCES------RPCQNGATCMAQPSGYLCQCAP 958
Query: 398 GYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECT 455
GY D NC E+D C+ CH CT PG + C C G+ G C VDEC
Sbjct: 959 GY---DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACPPGFV--GLRCEGDVDECL 1011
Query: 456 EGSHTCH--HSARCVNIDGGFRCEC 478
+ CH +A C ++ F C+C
Sbjct: 1012 D--QPCHPTGTAACHSLANAFYCQC 1034
Score = 81.8 bits (193), Expect = 7e-15
Identities = 76/276 (27%), Positives = 102/276 (36%), Gaps = 32/276 (11%)
Query: 221 CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECA 280
C+ C++G +C P C P H G C T C+ + G
Sbjct: 733 CHSGPCLNGG-SCNPSP-GGYYCTCPPSHTGPQCQTSTDYCVS-APCFNGGTCVNRPGTF 789
Query: 281 ECVCHDGNMQCTRVDPEL--ACPRLPCDPPQ--QFSVPGECCKFCPGV----------DY 326
C+C G Q R + +L +C PC Q S G C CP V D
Sbjct: 790 SCLCAMG-FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTVYTGGSCQTLMDL 847
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH----CHSNT 382
C C N+ C+ + C C QG+ G L + CQ+A G CH+
Sbjct: 848 CAQ-KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
CV+ Y C C G+ + V+ CE C A C P Y C+C GY+
Sbjct: 906 LCVDSGPSYFCHCPPGF--QGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYD 961
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + +D C S CH+ C GGF C C
Sbjct: 962 GQNCS-KELDACQ--SQPCHNHGTCTPKPGGFHCAC 994
Score = 78.2 bits (184), Expect = 9e-14
Identities = 84/292 (28%), Positives = 117/292 (40%), Gaps = 32/292 (10%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHP-GEC 253
EQC + C +N V+ +C C G E D EC ++P P G
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPG-FEGHACERDVNECFQDPGPCPKGTS 210
Query: 254 CPTCLR--QCLLWGNLYEHGERFAPKE--CAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C L QCL + + G R + C C +G C ++ PE C P
Sbjct: 211 CHNTLGSFQCLC--PVGQEGPRCELRAGPCPPRGCSNGGT-C-QLMPEKDSTFHLCLCPP 266
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
F P C+ P D C + H C TC + YTC C + + G + +DVDEC+
Sbjct: 267 GFIGPD--CEVNP--DNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS-EDVDECET 320
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTN 428
G HC + C N G + C C+ G+ +C E +D+C T C + C +
Sbjct: 321 QGP---PHCRNGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAAT--CAPGSTCID 372
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVN--IDGGFRCEC 478
GS++C C G G C D C S CH A+C + G C C
Sbjct: 373 RVGSFSCLCPPG--RTGLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLC 420
Score = 77.0 bits (181), Expect = 2e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 20/153 (13%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ C +TC++L + C C G +G C+ + +EC A L+ CH ++
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQ--LCEVETNECASAPCLNHADCH------DL 531
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ G+ C CL G++ C E +DEC + C C + PG++ C+C G+EG
Sbjct: 532 LNGFQCICLPGFSGT---RCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFEGP-- 584
Query: 447 TCM-HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C VDEC S C A C+++ G F C C
Sbjct: 585 RCQTEVDECL--SDPCPVGASCLDLPGAFFCLC 615
Score = 75.8 bits (178), Expect = 5e-13
Identities = 67/219 (30%), Positives = 87/219 (39%), Gaps = 36/219 (16%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP-GECCKFCPGVDYCN--------MGH 331
C C G D C PC + P G C+ PG D N
Sbjct: 916 CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ 975
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCH--SNTRCVNVV 388
C + TC + C C GF G L C+ DVDEC + CH C ++
Sbjct: 976 PCHNHGTCTPKPGGFHCACPPGFVG--LRCEGDVDECLD------QPCHPTGTAACHSLA 1027
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS---YTCRCRDGYEGDG 445
+ CQCL G+T ++ VE+D C ++ C C T GS + C C G+EG
Sbjct: 1028 NAFYCQCLPGHT--GQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGFEGP- 1082
Query: 446 YTCMH-VDECTEGSHTCHHSARCV-NIDGGF--RCECFT 480
TC H C G H CHH C+ + GF RC C +
Sbjct: 1083 -TCSHRAPSC--GFHHCHHGGLCLPSPKPGFPPRCACLS 1118
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + +C +TC++ ++C C G GL C D C CH + +
Sbjct: 356 LDDC-IAATCAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLS------QPCHGDAQ 406
Query: 384 CVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG---CHADAVCTNTPGSYTCRCR 438
C + G +C C GY+ ++DEC G C C NTPGS+ C C
Sbjct: 407 CSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 464
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY G H +EC S CH + C+++ F C C
Sbjct: 465 PGYTGSRCEADH-NECL--SQPCHPGSTCLDLLATFHCLC 501
Score = 68.5 bits (160), Expect = 7e-11
Identities = 54/212 (25%), Positives = 72/212 (33%), Gaps = 15/212 (7%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
K+ A C+C DG+ C + C C G C + C
Sbjct: 644 KDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 703
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC + Y C C G+ G TC + E H C + C GGY C C
Sbjct: 704 GTCYPQPSGYNCTCPTGYTGP--TCSE-----EMTACHSGPCLNGGSCNPSPGGYYCTCP 756
Query: 397 GGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
+T C D C C C N PG+++C C G++G C
Sbjct: 757 PSHTGPQ---CQTSTDYCVSAP--CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
Query: 456 EGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+ C + A C + G RC C T SC
Sbjct: 812 DS--PCRNRATCQDSPQGPRCLCPTVYTGGSC 841
Score = 65.7 bits (153), Expect = 5e-10
Identities = 69/246 (28%), Positives = 87/246 (35%), Gaps = 35/246 (14%)
Query: 224 CSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPKECAE 281
C C G R E D EC + HPG C L CL L ECA
Sbjct: 461 CLCPPGYTGSR-CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECAS 519
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMN 341
C + + C + C LP FS G C+ +D C C C +
Sbjct: 520 APCLN-HADCHDLLNGFQCICLP-----GFS--GTRCE--EDIDECRSS-PCANGGQCQD 568
Query: 342 LNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ CKC GF+G CQ +VDEC C C+++ G + C C G+T
Sbjct: 569 QPGAFHCKCLPGFEGP--RCQTEVDECLS------DPCPVGASCLDLPGAFFCLCPSGFT 620
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG-----DGYTCMHVDECT 455
+ EV C N C +C + C C DG G D TC H C
Sbjct: 621 GQ----LCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH-GHCQ 673
Query: 456 EGSHTC 461
S C
Sbjct: 674 RSSCVC 679
Score = 64.5 bits (150), Expect = 1e-09
Identities = 81/321 (25%), Positives = 111/321 (34%), Gaps = 67/321 (20%)
Query: 218 QRDCNRCSCVHGEITCRPVE---------CDRAECKNPVLHPGECCPTCLRQCLLWGNLY 268
Q+D C C G C P E C R+ C V G C L C+
Sbjct: 643 QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCI--SAPC 700
Query: 269 EHGERFAPKECA-ECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCP---- 322
HG P+ C C G T + AC PC + PG CP
Sbjct: 701 AHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
Query: 323 ------GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-----------------DGL 359
DYC + C TC+N ++C C GFQG +
Sbjct: 761 GPQCQTSTDYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 360 TCQDVDE--------------CQEAGGLHGHH-CHSNTRCVNVVGGYVCQCLGGYT---- 400
TCQD + CQ L C N+ C+ + C CL G+T
Sbjct: 820 TCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 401 RKDKFNCVEVDECEG--NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECTEG 457
+C + +G + CH +C ++ SY C C G++G C HV+ C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS--LCQDHVNPCE-- 935
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S C + A C+ G+ C+C
Sbjct: 936 SRPCQNGATCMAQPSGYLCQC 956
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 23/172 (13%)
Query: 333 CDENATCMNL----NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
C TC + +T + C C GF G C+ + D C H C + C +
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPD--CEVNPDNCVS------HQCQNGGTCQDG 294
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECE--GNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+ Y C C +T D C E VDECE G H C C N+ GS+ C C G+ G
Sbjct: 295 LDTYTCLCPETWTGWD---CSEDVDECETQGPPH-CRNGGTCQNSAGSFHCVCVSGWGGT 350
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
++D+C TC + C++ G F C C L C + +S+
Sbjct: 351 SCE-ENLDDCIAA--TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ 399
Score = 61.7 bits (143), Expect = 8e-09
Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 26/177 (14%)
Query: 315 GECCKF---CPGVDYCNMGHSCDE--------NATCMNLNTKYTCKCNQGFQGDGLTCQD 363
GE C+F C C G SC ++ L + C C GF G+ +
Sbjct: 59 GETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL 118
Query: 364 VDECQEAGGLHGHHCHSNTRC-VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
D C + C RC + G C C+ G+T + C D C N C
Sbjct: 119 EDPCPPS------FCSKRGRCHIQASGRPQCSCMPGWTGE---QCQLRDFCSANP--CVN 167
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC T C C G+E G+ C V+EC + C C N G F+C C
Sbjct: 168 GGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/262 (25%), Positives = 100/262 (38%), Gaps = 29/262 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPV--ECDRAEC- 243
G + LE + C+ + + T C C + TC EC A+
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLC-LCQPGYSGPTCHQDLDECLMAQQG 442
Query: 244 KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAP-KECAECVCHDGNMQCTRVDPELACPR 302
+P H G C T L Y A EC CH G+ C + LA
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDL---LATFH 498
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
C P + G+ C+ + C C +A C +L + C C GF G +
Sbjct: 499 CLCPP----GLEGQLCEV--ETNECASA-PCLNHADCHDLLNGFQCICLPGFSGTRCE-E 550
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCH 421
D+DEC+ + C + +C + G + C+CL G+ C EVDEC + C
Sbjct: 551 DIDECRSSP------CANGGQCQDQPGAFHCKCLPGFEGP---RCQTEVDECLSDP--CP 599
Query: 422 ADAVCTNTPGSYTCRCRDGYEG 443
A C + PG++ C C G+ G
Sbjct: 600 VGASCLDLPGAFFCLCPSGFTG 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 16/190 (8%)
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT 360
P++ C P F G C+ + + G C + +C N + C C G +G
Sbjct: 176 PQIQCHCPPGFE--GHACERDVNECFQDPG-PCPKGTSCHNTLGSFQCLCPVGQEGPRCE 232
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHG 419
+ C G +G C + ++C C G+ D C V D C +H
Sbjct: 233 LR-AGPCPPRGCSNGGTCQLMPEKDSTF--HLCLCPPGFIGPD---CEVNPDNCV--SHQ 284
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDEC-TEGSHTCHHSARCVNIDGGFRCE 477
C C + +YTC C + + G + C VDEC T+G C + C N G F C
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTG--WDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 478 CFTENCELSC 487
C + SC
Sbjct: 343 CVSGWGGTSC 352
Score = 39.1 bits (87), Expect = 0.048
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 333 CDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C + C + + + C C G+ G+ CQ D C + C + C+
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCS------ANPCVNGGVCLATYPQI 178
Query: 392 VCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C G+ + C +V+EC + C C NT GS+ C C G EG
Sbjct: 179 QCHCPPGF---EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 87.4 bits (207), Expect = 1e-16
Identities = 61/205 (29%), Positives = 84/205 (40%), Gaps = 23/205 (11%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA+ C N C + P C L ++P C+ ++ C
Sbjct: 848 CAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 339 CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLG 397
C++ Y C C GFQG CQD V+ C+ C + C+ GY+CQC
Sbjct: 907 CVDSGPSYFCHCPPGFQGS--LCQDHVNPCES------RPCQNGATCMAQPSGYLCQCAP 958
Query: 398 GYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECT 455
GY D NC E+D C+ CH CT PG + C C G+ G C VDEC
Sbjct: 959 GY---DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACPPGFV--GLRCEGDVDECL 1011
Query: 456 EGSHTCH--HSARCVNIDGGFRCEC 478
+ CH +A C ++ F C+C
Sbjct: 1012 D--QPCHPTGTAACHSLANAFYCQC 1034
Score = 81.8 bits (193), Expect = 7e-15
Identities = 76/276 (27%), Positives = 102/276 (36%), Gaps = 32/276 (11%)
Query: 221 CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECA 280
C+ C++G +C P C P H G C T C+ + G
Sbjct: 733 CHSGPCLNGG-SCNPSP-GGYYCTCPPSHTGPQCQTSTDYCVS-APCFNGGTCVNRPGTF 789
Query: 281 ECVCHDGNMQCTRVDPEL--ACPRLPCDPPQ--QFSVPGECCKFCPGV----------DY 326
C+C G Q R + +L +C PC Q S G C CP V D
Sbjct: 790 SCLCAMG-FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTVYTGGSCQTLMDL 847
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH----CHSNT 382
C C N+ C+ + C C QG+ G L + CQ+A G CH+
Sbjct: 848 CAQ-KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
CV+ Y C C G+ + V+ CE C A C P Y C+C GY+
Sbjct: 906 LCVDSGPSYFCHCPPGF--QGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYD 961
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + +D C S CH+ C GGF C C
Sbjct: 962 GQNCS-KELDACQ--SQPCHNHGTCTPKPGGFHCAC 994
Score = 78.2 bits (184), Expect = 9e-14
Identities = 84/292 (28%), Positives = 117/292 (40%), Gaps = 32/292 (10%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHP-GEC 253
EQC + C +N V+ +C C G E D EC ++P P G
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPG-FEGHACERDVNECFQDPGPCPKGTS 210
Query: 254 CPTCLR--QCLLWGNLYEHGERFAPKE--CAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C L QCL + + G R + C C +G C ++ PE C P
Sbjct: 211 CHNTLGSFQCLC--PVGQEGPRCELRAGPCPPRGCSNGGT-C-QLMPEKDSTFHLCLCPP 266
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
F P C+ P D C + H C TC + YTC C + + G + +DVDEC+
Sbjct: 267 GFIGPD--CEVNP--DNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS-EDVDECET 320
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTN 428
G HC + C N G + C C+ G+ +C E +D+C T C + C +
Sbjct: 321 QGP---PHCRNGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAAT--CAPGSTCID 372
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVN--IDGGFRCEC 478
GS++C C G G C D C S CH A+C + G C C
Sbjct: 373 RVGSFSCLCPPG--RTGLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLC 420
Score = 77.0 bits (181), Expect = 2e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 20/153 (13%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ C +TC++L + C C G +G C+ + +EC A L+ CH ++
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQ--LCEVETNECASAPCLNHADCH------DL 531
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ G+ C CL G++ C E +DEC + C C + PG++ C+C G+EG
Sbjct: 532 LNGFQCICLPGFSGT---RCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFEGP-- 584
Query: 447 TCM-HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C VDEC S C A C+++ G F C C
Sbjct: 585 RCQTEVDECL--SDPCPVGASCLDLPGAFFCLC 615
Score = 75.8 bits (178), Expect = 5e-13
Identities = 67/219 (30%), Positives = 87/219 (39%), Gaps = 36/219 (16%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP-GECCKFCPGVDYCN--------MGH 331
C C G D C PC + P G C+ PG D N
Sbjct: 916 CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ 975
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCH--SNTRCVNVV 388
C + TC + C C GF G L C+ DVDEC + CH C ++
Sbjct: 976 PCHNHGTCTPKPGGFHCACPPGFVG--LRCEGDVDECLD------QPCHPTGTAACHSLA 1027
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS---YTCRCRDGYEGDG 445
+ CQCL G+T ++ VE+D C ++ C C T GS + C C G+EG
Sbjct: 1028 NAFYCQCLPGHT--GQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGFEGP- 1082
Query: 446 YTCMH-VDECTEGSHTCHHSARCV-NIDGGF--RCECFT 480
TC H C G H CHH C+ + GF RC C +
Sbjct: 1083 -TCSHRAPSC--GFHHCHHGGLCLPSPKPGFPPRCACLS 1118
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + +C +TC++ ++C C G GL C D C CH + +
Sbjct: 356 LDDC-IAATCAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLS------QPCHGDAQ 406
Query: 384 CVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG---CHADAVCTNTPGSYTCRCR 438
C + G +C C GY+ ++DEC G C C NTPGS+ C C
Sbjct: 407 CSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 464
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY G H +EC S CH + C+++ F C C
Sbjct: 465 PGYTGSRCEADH-NECL--SQPCHPGSTCLDLLATFHCLC 501
Score = 68.5 bits (160), Expect = 7e-11
Identities = 54/212 (25%), Positives = 72/212 (33%), Gaps = 15/212 (7%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
K+ A C+C DG+ C + C C G C + C
Sbjct: 644 KDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 703
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC + Y C C G+ G TC + E H C + C GGY C C
Sbjct: 704 GTCYPQPSGYNCTCPTGYTGP--TCSE-----EMTACHSGPCLNGGSCNPSPGGYYCTCP 756
Query: 397 GGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
+T C D C C C N PG+++C C G++G C
Sbjct: 757 PSHTGPQ---CQTSTDYCVSAP--CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
Query: 456 EGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+ C + A C + G RC C T SC
Sbjct: 812 DS--PCRNRATCQDSPQGPRCLCPTVYTGGSC 841
Score = 65.7 bits (153), Expect = 5e-10
Identities = 69/246 (28%), Positives = 87/246 (35%), Gaps = 35/246 (14%)
Query: 224 CSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPKECAE 281
C C G R E D EC + HPG C L CL L ECA
Sbjct: 461 CLCPPGYTGSR-CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECAS 519
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMN 341
C + + C + C LP FS G C+ +D C C C +
Sbjct: 520 APCLN-HADCHDLLNGFQCICLP-----GFS--GTRCE--EDIDECRSS-PCANGGQCQD 568
Query: 342 LNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ CKC GF+G CQ +VDEC C C+++ G + C C G+T
Sbjct: 569 QPGAFHCKCLPGFEGP--RCQTEVDECLS------DPCPVGASCLDLPGAFFCLCPSGFT 620
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG-----DGYTCMHVDECT 455
+ EV C N C +C + C C DG G D TC H C
Sbjct: 621 GQ----LCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH-GHCQ 673
Query: 456 EGSHTC 461
S C
Sbjct: 674 RSSCVC 679
Score = 64.5 bits (150), Expect = 1e-09
Identities = 81/321 (25%), Positives = 111/321 (34%), Gaps = 67/321 (20%)
Query: 218 QRDCNRCSCVHGEITCRPVE---------CDRAECKNPVLHPGECCPTCLRQCLLWGNLY 268
Q+D C C G C P E C R+ C V G C L C+
Sbjct: 643 QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCI--SAPC 700
Query: 269 EHGERFAPKECA-ECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCP---- 322
HG P+ C C G T + AC PC + PG CP
Sbjct: 701 AHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
Query: 323 ------GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-----------------DGL 359
DYC + C TC+N ++C C GFQG +
Sbjct: 761 GPQCQTSTDYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 360 TCQDVDE--------------CQEAGGLHGHH-CHSNTRCVNVVGGYVCQCLGGYT---- 400
TCQD + CQ L C N+ C+ + C CL G+T
Sbjct: 820 TCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 401 RKDKFNCVEVDECEG--NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECTEG 457
+C + +G + CH +C ++ SY C C G++G C HV+ C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS--LCQDHVNPCE-- 935
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S C + A C+ G+ C+C
Sbjct: 936 SRPCQNGATCMAQPSGYLCQC 956
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 23/172 (13%)
Query: 333 CDENATCMNL----NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
C TC + +T + C C GF G C+ + D C H C + C +
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPD--CEVNPDNCVS------HQCQNGGTCQDG 294
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECE--GNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+ Y C C +T D C E VDECE G H C C N+ GS+ C C G+ G
Sbjct: 295 LDTYTCLCPETWTGWD---CSEDVDECETQGPPH-CRNGGTCQNSAGSFHCVCVSGWGGT 350
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
++D+C TC + C++ G F C C L C + +S+
Sbjct: 351 SCE-ENLDDCIAA--TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ 399
Score = 61.7 bits (143), Expect = 8e-09
Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 26/177 (14%)
Query: 315 GECCKF---CPGVDYCNMGHSCDE--------NATCMNLNTKYTCKCNQGFQGDGLTCQD 363
GE C+F C C G SC ++ L + C C GF G+ +
Sbjct: 59 GETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL 118
Query: 364 VDECQEAGGLHGHHCHSNTRC-VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
D C + C RC + G C C+ G+T + C D C N C
Sbjct: 119 EDPCPPS------FCSKRGRCHIQASGRPQCSCMPGWTGE---QCQLRDFCSANP--CVN 167
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC T C C G+E G+ C V+EC + C C N G F+C C
Sbjct: 168 GGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/262 (25%), Positives = 100/262 (38%), Gaps = 29/262 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPV--ECDRAEC- 243
G + LE + C+ + + T C C + TC EC A+
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLC-LCQPGYSGPTCHQDLDECLMAQQG 442
Query: 244 KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAP-KECAECVCHDGNMQCTRVDPELACPR 302
+P H G C T L Y A EC CH G+ C + LA
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDL---LATFH 498
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
C P + G+ C+ + C C +A C +L + C C GF G +
Sbjct: 499 CLCPP----GLEGQLCEV--ETNECASA-PCLNHADCHDLLNGFQCICLPGFSGTRCE-E 550
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCH 421
D+DEC+ + C + +C + G + C+CL G+ C EVDEC + C
Sbjct: 551 DIDECRSSP------CANGGQCQDQPGAFHCKCLPGFEGP---RCQTEVDECLSDP--CP 599
Query: 422 ADAVCTNTPGSYTCRCRDGYEG 443
A C + PG++ C C G+ G
Sbjct: 600 VGASCLDLPGAFFCLCPSGFTG 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 16/190 (8%)
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT 360
P++ C P F G C+ + + G C + +C N + C C G +G
Sbjct: 176 PQIQCHCPPGFE--GHACERDVNECFQDPG-PCPKGTSCHNTLGSFQCLCPVGQEGPRCE 232
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHG 419
+ C G +G C + ++C C G+ D C V D C +H
Sbjct: 233 LR-AGPCPPRGCSNGGTCQLMPEKDSTF--HLCLCPPGFIGPD---CEVNPDNCV--SHQ 284
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDEC-TEGSHTCHHSARCVNIDGGFRCE 477
C C + +YTC C + + G + C VDEC T+G C + C N G F C
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTG--WDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 478 CFTENCELSC 487
C + SC
Sbjct: 343 CVSGWGGTSC 352
Score = 39.1 bits (87), Expect = 0.048
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 333 CDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C + C + + + C C G+ G+ CQ D C + C + C+
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCS------ANPCVNGGVCLATYPQI 178
Query: 392 VCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C G+ + C +V+EC + C C NT GS+ C C G EG
Sbjct: 179 QCHCPPGF---EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 87.4 bits (207), Expect = 1e-16
Identities = 61/205 (29%), Positives = 84/205 (40%), Gaps = 23/205 (11%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA+ C N C + P C L ++P C+ ++ C
Sbjct: 848 CAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 339 CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLG 397
C++ Y C C GFQG CQD V+ C+ C + C+ GY+CQC
Sbjct: 907 CVDSGPSYFCHCPPGFQGS--LCQDHVNPCES------RPCQNGATCMAQPSGYLCQCAP 958
Query: 398 GYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECT 455
GY D NC E+D C+ CH CT PG + C C G+ G C VDEC
Sbjct: 959 GY---DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACPPGFV--GLRCEGDVDECL 1011
Query: 456 EGSHTCH--HSARCVNIDGGFRCEC 478
+ CH +A C ++ F C+C
Sbjct: 1012 D--QPCHPTGTAACHSLANAFYCQC 1034
Score = 80.6 bits (190), Expect = 2e-14
Identities = 75/276 (27%), Positives = 102/276 (36%), Gaps = 32/276 (11%)
Query: 221 CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECA 280
C+ C++G +C P C P H G C T C+ + G
Sbjct: 733 CHSGPCLNGG-SCNPSP-GGYYCTCPPSHTGPQCQTSTDYCVS-APCFNGGTCVNRPGTF 789
Query: 281 ECVCHDGNMQCTRVDPEL--ACPRLPCDPPQ--QFSVPGECCKFCPG----------VDY 326
C+C G Q R + +L +C PC Q S G C CP +D
Sbjct: 790 SCLCAMG-FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGGSCQTLMDL 847
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH----CHSNT 382
C C N+ C+ + C C QG+ G L + CQ+A G CH+
Sbjct: 848 CAQ-KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
CV+ Y C C G+ + V+ CE C A C P Y C+C GY+
Sbjct: 906 LCVDSGPSYFCHCPPGF--QGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYD 961
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + +D C S CH+ C GGF C C
Sbjct: 962 GQNCS-KELDACQ--SQPCHNHGTCTPKPGGFHCAC 994
Score = 78.2 bits (184), Expect = 9e-14
Identities = 84/292 (28%), Positives = 117/292 (40%), Gaps = 32/292 (10%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHP-GEC 253
EQC + C +N V+ +C C G E D EC ++P P G
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPG-FEGHACERDVNECFQDPGPCPKGTS 210
Query: 254 CPTCLR--QCLLWGNLYEHGERFAPKE--CAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C L QCL + + G R + C C +G C ++ PE C P
Sbjct: 211 CHNTLGSFQCLC--PVGQEGPRCELRAGPCPPRGCSNGGT-C-QLMPEKDSTFHLCLCPP 266
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
F P C+ P D C + H C TC + YTC C + + G + +DVDEC+
Sbjct: 267 GFIGPD--CEVNP--DNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS-EDVDECET 320
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTN 428
G HC + C N G + C C+ G+ +C E +D+C T C + C +
Sbjct: 321 QGP---PHCRNGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAAT--CAPGSTCID 372
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVN--IDGGFRCEC 478
GS++C C G G C D C S CH A+C + G C C
Sbjct: 373 RVGSFSCLCPPG--RTGLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLC 420
Score = 77.0 bits (181), Expect = 2e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 20/153 (13%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ C +TC++L + C C G +G C+ + +EC A L+ CH ++
Sbjct: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQ--LCEVETNECASAPCLNHADCH------DL 531
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ G+ C CL G++ C E +DEC + C C + PG++ C+C G+EG
Sbjct: 532 LNGFQCICLPGFSGT---RCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFEGP-- 584
Query: 447 TCM-HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C VDEC S C A C+++ G F C C
Sbjct: 585 RCQTEVDECL--SDPCPVGASCLDLPGAFFCLC 615
Score = 75.8 bits (178), Expect = 5e-13
Identities = 67/219 (30%), Positives = 87/219 (39%), Gaps = 36/219 (16%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP-GECCKFCPGVDYCN--------MGH 331
C C G D C PC + P G C+ PG D N
Sbjct: 916 CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ 975
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCH--SNTRCVNVV 388
C + TC + C C GF G L C+ DVDEC + CH C ++
Sbjct: 976 PCHNHGTCTPKPGGFHCACPPGFVG--LRCEGDVDECLD------QPCHPTGTAACHSLA 1027
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS---YTCRCRDGYEGDG 445
+ CQCL G+T ++ VE+D C ++ C C T GS + C C G+EG
Sbjct: 1028 NAFYCQCLPGHT--GQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGFEGP- 1082
Query: 446 YTCMH-VDECTEGSHTCHHSARCV-NIDGGF--RCECFT 480
TC H C G H CHH C+ + GF RC C +
Sbjct: 1083 -TCSHRAPSC--GFHHCHHGGLCLPSPKPGFPPRCACLS 1118
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + +C +TC++ ++C C G GL C D C CH + +
Sbjct: 356 LDDC-IAATCAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLS------QPCHGDAQ 406
Query: 384 CVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG---CHADAVCTNTPGSYTCRCR 438
C + G +C C GY+ ++DEC G C C NTPGS+ C C
Sbjct: 407 CSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 464
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY G H +EC S CH + C+++ F C C
Sbjct: 465 PGYTGSRCEADH-NECL--SQPCHPGSTCLDLLATFHCLC 501
Score = 68.5 bits (160), Expect = 7e-11
Identities = 54/212 (25%), Positives = 72/212 (33%), Gaps = 15/212 (7%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
K+ A C+C DG+ C + C C G C + C
Sbjct: 644 KDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 703
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC + Y C C G+ G TC + E H C + C GGY C C
Sbjct: 704 GTCYPQPSGYNCTCPTGYTGP--TCSE-----EMTACHSGPCLNGGSCNPSPGGYYCTCP 756
Query: 397 GGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
+T C D C C C N PG+++C C G++G C
Sbjct: 757 PSHTGPQ---CQTSTDYCVSAP--CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
Query: 456 EGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+ C + A C + G RC C T SC
Sbjct: 812 DS--PCRNRATCQDSPQGPRCLCPTGYTGGSC 841
Score = 65.7 bits (153), Expect = 5e-10
Identities = 69/246 (28%), Positives = 87/246 (35%), Gaps = 35/246 (14%)
Query: 224 CSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPKECAE 281
C C G R E D EC + HPG C L CL L ECA
Sbjct: 461 CLCPPGYTGSR-CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECAS 519
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMN 341
C + + C + C LP FS G C+ +D C C C +
Sbjct: 520 APCLN-HADCHDLLNGFQCICLP-----GFS--GTRCE--EDIDECRSS-PCANGGQCQD 568
Query: 342 LNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ CKC GF+G CQ +VDEC C C+++ G + C C G+T
Sbjct: 569 QPGAFHCKCLPGFEGP--RCQTEVDECLS------DPCPVGASCLDLPGAFFCLCPSGFT 620
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG-----DGYTCMHVDECT 455
+ EV C N C +C + C C DG G D TC H C
Sbjct: 621 GQ----LCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH-GHCQ 673
Query: 456 EGSHTC 461
S C
Sbjct: 674 RSSCVC 679
Score = 65.3 bits (152), Expect = 6e-10
Identities = 81/321 (25%), Positives = 112/321 (34%), Gaps = 67/321 (20%)
Query: 218 QRDCNRCSCVHGEITCRPVE---------CDRAECKNPVLHPGECCPTCLRQCLLWGNLY 268
Q+D C C G C P E C R+ C V G C L C+
Sbjct: 643 QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCI--SAPC 700
Query: 269 EHGERFAPKECA-ECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCP---- 322
HG P+ C C G T + AC PC + PG CP
Sbjct: 701 AHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 760
Query: 323 ------GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-----------------DGL 359
DYC + C TC+N ++C C GFQG +
Sbjct: 761 GPQCQTSTDYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 360 TCQDVDE---CQEAGGLHGHHCHS------------NTRCVNVVGGYVCQCLGGYT---- 400
TCQD + C G G C + N+ C+ + C CL G+T
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 401 RKDKFNCVEVDECEG--NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECTEG 457
+C + +G + CH +C ++ SY C C G++G C HV+ C
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS--LCQDHVNPCE-- 935
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S C + A C+ G+ C+C
Sbjct: 936 SRPCQNGATCMAQPSGYLCQC 956
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 23/172 (13%)
Query: 333 CDENATCMNL----NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
C TC + +T + C C GF G C+ + D C H C + C +
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPD--CEVNPDNCVS------HQCQNGGTCQDG 294
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECE--GNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+ Y C C +T D C E VDECE G H C C N+ GS+ C C G+ G
Sbjct: 295 LDTYTCLCPETWTGWD---CSEDVDECETQGPPH-CRNGGTCQNSAGSFHCVCVSGWGGT 350
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
++D+C TC + C++ G F C C L C + +S+
Sbjct: 351 SCE-ENLDDCIAA--TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ 399
Score = 61.7 bits (143), Expect = 8e-09
Identities = 49/177 (27%), Positives = 65/177 (36%), Gaps = 26/177 (14%)
Query: 315 GECCKF---CPGVDYCNMGHSCDE--------NATCMNLNTKYTCKCNQGFQGDGLTCQD 363
GE C+F C C G SC ++ L + C C GF G+ +
Sbjct: 59 GETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL 118
Query: 364 VDECQEAGGLHGHHCHSNTRC-VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
D C + C RC + G C C+ G+T + C D C N C
Sbjct: 119 EDPCPPS------FCSKRGRCHIQASGRPQCSCMPGWTGE---QCQLRDFCSANP--CVN 167
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC T C C G+E G+ C V+EC + C C N G F+C C
Sbjct: 168 GGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 222
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/262 (25%), Positives = 100/262 (38%), Gaps = 29/262 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPV--ECDRAEC- 243
G + LE + C+ + + T C C + TC EC A+
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLC-LCQPGYSGPTCHQDLDECLMAQQG 442
Query: 244 KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAP-KECAECVCHDGNMQCTRVDPELACPR 302
+P H G C T L Y A EC CH G+ C + LA
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDL---LATFH 498
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
C P + G+ C+ + C C +A C +L + C C GF G +
Sbjct: 499 CLCPP----GLEGQLCEV--ETNECASA-PCLNHADCHDLLNGFQCICLPGFSGTRCE-E 550
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCH 421
D+DEC+ + C + +C + G + C+CL G+ C EVDEC + C
Sbjct: 551 DIDECRSSP------CANGGQCQDQPGAFHCKCLPGFEGP---RCQTEVDECLSDP--CP 599
Query: 422 ADAVCTNTPGSYTCRCRDGYEG 443
A C + PG++ C C G+ G
Sbjct: 600 VGASCLDLPGAFFCLCPSGFTG 621
Score = 60.1 bits (139), Expect = 2e-08
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 16/190 (8%)
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT 360
P++ C P F G C+ + + G C + +C N + C C G +G
Sbjct: 176 PQIQCHCPPGFE--GHACERDVNECFQDPG-PCPKGTSCHNTLGSFQCLCPVGQEGPRCE 232
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHG 419
+ C G +G C + ++C C G+ D C V D C +H
Sbjct: 233 LR-AGPCPPRGCSNGGTCQLMPEKDSTF--HLCLCPPGFIGPD---CEVNPDNCV--SHQ 284
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDEC-TEGSHTCHHSARCVNIDGGFRCE 477
C C + +YTC C + + G + C VDEC T+G C + C N G F C
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTG--WDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
Query: 478 CFTENCELSC 487
C + SC
Sbjct: 343 CVSGWGGTSC 352
Score = 39.1 bits (87), Expect = 0.048
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 333 CDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C + C + + + C C G+ G+ CQ D C + C + C+
Sbjct: 127 CSKRGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCS------ANPCVNGGVCLATYPQI 178
Query: 392 VCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C G+ + C +V+EC + C C NT GS+ C C G EG
Sbjct: 179 QCHCPPGF---EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEG 228
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2005
Score = 87.4 bits (207), Expect = 1e-16
Identities = 61/205 (29%), Positives = 84/205 (40%), Gaps = 23/205 (11%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA+ C N C + P C L ++P C+ ++ C
Sbjct: 850 CAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 908
Query: 339 CMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLG 397
C++ Y C C GFQG CQD V+ C+ C + C+ GY+CQC
Sbjct: 909 CVDSGPSYFCHCPPGFQGS--LCQDHVNPCES------RPCQNGATCMAQPSGYLCQCAP 960
Query: 398 GYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECT 455
GY D NC E+D C+ CH CT PG + C C G+ G C VDEC
Sbjct: 961 GY---DGQNCSKELDACQSQP--CHNHGTCTPKPGGFHCACPPGFV--GLRCEGDVDECL 1013
Query: 456 EGSHTCH--HSARCVNIDGGFRCEC 478
+ CH +A C ++ F C+C
Sbjct: 1014 D--QPCHPTGTAACHSLANAFYCQC 1036
Score = 80.6 bits (190), Expect = 2e-14
Identities = 75/276 (27%), Positives = 102/276 (36%), Gaps = 32/276 (11%)
Query: 221 CNRCSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLRQCLLWGNLYEHGERFAPKECA 280
C+ C++G +C P C P H G C T C+ + G
Sbjct: 735 CHSGPCLNGG-SCNPSP-GGYYCTCPPSHTGPQCQTSTDYCVS-APCFNGGTCVNRPGTF 791
Query: 281 ECVCHDGNMQCTRVDPEL--ACPRLPCDPPQ--QFSVPGECCKFCPG----------VDY 326
C+C G Q R + +L +C PC Q S G C CP +D
Sbjct: 792 SCLCAMG-FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC-LCPTGYTGGSCQTLMDL 849
Query: 327 CNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHH----CHSNT 382
C C N+ C+ + C C QG+ G L + CQ+A G CH+
Sbjct: 850 CAQ-KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLSSCQKAALSQGIDVSSLCHNGG 907
Query: 383 RCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYE 442
CV+ Y C C G+ + V+ CE C A C P Y C+C GY+
Sbjct: 908 LCVDSGPSYFCHCPPGF--QGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYD 963
Query: 443 GDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
G + +D C S CH+ C GGF C C
Sbjct: 964 GQNCS-KELDACQ--SQPCHNHGTCTPKPGGFHCAC 996
Score = 78.2 bits (184), Expect = 9e-14
Identities = 84/292 (28%), Positives = 117/292 (40%), Gaps = 32/292 (10%)
Query: 196 EQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPVECDRAEC-KNPVLHP-GEC 253
EQC + C +N V+ +C C G E D EC ++P P G
Sbjct: 154 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPG-FEGHACERDVNECFQDPGPCPKGTS 212
Query: 254 CPTCLR--QCLLWGNLYEHGERFAPKE--CAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
C L QCL + + G R + C C +G C ++ PE C P
Sbjct: 213 CHNTLGSFQCLC--PVGQEGPRCELRAGPCPPRGCSNGGT-C-QLMPEKDSTFHLCLCPP 268
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQE 369
F P C+ P D C + H C TC + YTC C + + G + +DVDEC+
Sbjct: 269 GFIGPD--CEVNP--DNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS-EDVDECEA 322
Query: 370 AGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTN 428
G HC + C N G + C C+ G+ +C E +D+C T C + C +
Sbjct: 323 QGP---PHCRNGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAAT--CAPGSTCID 374
Query: 429 TPGSYTCRCRDGYEGDGYTCMHVDECTEGSHTCHHSARCVN--IDGGFRCEC 478
GS++C C G G C D C S CH A+C + G C C
Sbjct: 375 RVGSFSCLCPPG--RTGLLCHLEDMCL--SQPCHGDAQCSTNPLTGSTLCLC 422
Score = 77.0 bits (181), Expect = 2e-13
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 20/153 (13%)
Query: 329 MGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
+ C +TC++L + C C G +G C+ + +EC A L+ CH ++
Sbjct: 482 LSQPCHPGSTCLDLLATFHCLCPPGLEGQ--LCEVETNECASAPCLNHADCH------DL 533
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGY 446
+ G+ C CL G++ C E +DEC + C C + PG++ C+C G+EG
Sbjct: 534 LNGFQCICLPGFSGT---RCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGFEGP-- 586
Query: 447 TCM-HVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C VDEC S C A C+++ G F C C
Sbjct: 587 RCQTEVDECL--SDPCPVGASCLDLPGAFFCLC 617
Score = 75.8 bits (178), Expect = 5e-13
Identities = 67/219 (30%), Positives = 87/219 (39%), Gaps = 36/219 (16%)
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQ-FSVP-GECCKFCPGVDYCN--------MGH 331
C C G D C PC + P G C+ PG D N
Sbjct: 918 CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ 977
Query: 332 SCDENATCMNLNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCH--SNTRCVNVV 388
C + TC + C C GF G L C+ DVDEC + CH C ++
Sbjct: 978 PCHNHGTCTPKPGGFHCACPPGFVG--LRCEGDVDECLD------QPCHPTGTAACHSLA 1029
Query: 389 GGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHADAVCTNTPGS---YTCRCRDGYEGDG 445
+ CQCL G+T ++ VE+D C ++ C C T GS + C C G+EG
Sbjct: 1030 NAFYCQCLPGHT--GQWCEVEIDPC--HSQPCFHGGTCEATAGSPLGFICHCPKGFEGP- 1084
Query: 446 YTCMH-VDECTEGSHTCHHSARCV-NIDGGF--RCECFT 480
TC H C G H CHH C+ + GF RC C +
Sbjct: 1085 -TCSHRAPSC--GFHHCHHGGLCLPSPKPGFPPRCACLS 1120
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 19/160 (11%)
Query: 324 VDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTR 383
+D C + +C +TC++ ++C C G GL C D C CH + +
Sbjct: 358 LDDC-IAATCAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLS------QPCHGDAQ 408
Query: 384 CVN--VVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHG---CHADAVCTNTPGSYTCRCR 438
C + G +C C GY+ ++DEC G C C NTPGS+ C C
Sbjct: 409 CSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 466
Query: 439 DGYEGDGYTCMHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
GY G H +EC S CH + C+++ F C C
Sbjct: 467 PGYTGSRCEADH-NECL--SQPCHPGSTCLDLLATFHCLC 503
Score = 68.5 bits (160), Expect = 7e-11
Identities = 54/212 (25%), Positives = 72/212 (33%), Gaps = 15/212 (7%)
Query: 277 KECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDEN 336
K+ A C+C DG+ C + C C G C + C
Sbjct: 646 KDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 705
Query: 337 ATCMNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
TC + Y C C G+ G TC + E H C + C GGY C C
Sbjct: 706 GTCYPQPSGYNCTCPTGYTGP--TCSE-----EMTACHSGPCLNGGSCNPSPGGYYCTCP 758
Query: 397 GGYTRKDKFNC-VEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
+T C D C C C N PG+++C C G++G C
Sbjct: 759 PSHTGPQ---CQTSTDYCVSAP--CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 813
Query: 456 EGSHTCHHSARCVNIDGGFRCECFTENCELSC 487
+ C + A C + G RC C T SC
Sbjct: 814 DS--PCRNRATCQDSPQGPRCLCPTGYTGGSC 843
Score = 65.7 bits (153), Expect = 5e-10
Identities = 69/246 (28%), Positives = 87/246 (35%), Gaps = 35/246 (14%)
Query: 224 CSCVHGEITCRPVECDRAECKNPVLHPGECCPTCLR--QCLLWGNLYEHGERFAPKECAE 281
C C G R E D EC + HPG C L CL L ECA
Sbjct: 463 CLCPPGYTGSR-CEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECAS 521
Query: 282 CVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMN 341
C + + C + C LP FS G C+ +D C C C +
Sbjct: 522 APCLN-HADCHDLLNGFQCICLP-----GFS--GTRCE--EDIDECRSS-PCANGGQCQD 570
Query: 342 LNTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYT 400
+ CKC GF+G CQ +VDEC C C+++ G + C C G+T
Sbjct: 571 QPGAFHCKCLPGFEGP--RCQTEVDECLS------DPCPVGASCLDLPGAFFCLCPSGFT 622
Query: 401 RKDKFNCVEVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG-----DGYTCMHVDECT 455
+ EV C N C +C + C C DG G D TC H C
Sbjct: 623 GQ----LCEVPLCAPNL--CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH-GHCQ 675
Query: 456 EGSHTC 461
S C
Sbjct: 676 RSSCVC 681
Score = 65.3 bits (152), Expect = 6e-10
Identities = 81/321 (25%), Positives = 112/321 (34%), Gaps = 67/321 (20%)
Query: 218 QRDCNRCSCVHGEITCRPVE---------CDRAECKNPVLHPGECCPTCLRQCLLWGNLY 268
Q+D C C G C P E C R+ C V G C L C+
Sbjct: 645 QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCI--SAPC 702
Query: 269 EHGERFAPKECA-ECVCHDGNMQCTRVDPELACPRLPC-DPPQQFSVPGECCKFCP---- 322
HG P+ C C G T + AC PC + PG CP
Sbjct: 703 AHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT 762
Query: 323 ------GVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQG-----------------DGL 359
DYC + C TC+N ++C C GFQG +
Sbjct: 763 GPQCQTSTDYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 821
Query: 360 TCQDVDE---CQEAGGLHGHHCHS------------NTRCVNVVGGYVCQCLGGYT---- 400
TCQD + C G G C + N+ C+ + C CL G+T
Sbjct: 822 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 881
Query: 401 RKDKFNCVEVDECEG--NTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCM-HVDECTEG 457
+C + +G + CH +C ++ SY C C G++G C HV+ C
Sbjct: 882 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS--LCQDHVNPCE-- 937
Query: 458 SHTCHHSARCVNIDGGFRCEC 478
S C + A C+ G+ C+C
Sbjct: 938 SRPCQNGATCMAQPSGYLCQC 958
Score = 63.3 bits (147), Expect = 3e-09
Identities = 50/177 (28%), Positives = 65/177 (36%), Gaps = 26/177 (14%)
Query: 315 GECCKF---CPGVDYCNMGHSCDE--------NATCMNLNTKYTCKCNQGFQGDGLTCQD 363
GE C+F C C G SC ++ L + C C GF G+ Q
Sbjct: 61 GETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQL 120
Query: 364 VDECQEAGGLHGHHCHSNTRC-VNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
D C + C RC + G C C+ G+T + C D C N C
Sbjct: 121 EDPCPPS------FCSKRGRCHIQASGRPQCSCMPGWTGE---QCQLRDFCSANP--CVN 169
Query: 423 DAVCTNTPGSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
VC T C C G+E G+ C V+EC + C C N G F+C C
Sbjct: 170 GGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLC 224
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 23/172 (13%)
Query: 333 CDENATCMNL----NTKYTCKCNQGFQGDGLTCQ-DVDECQEAGGLHGHHCHSNTRCVNV 387
C TC + +T + C C GF G C+ + D C H C + C +
Sbjct: 245 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPD--CEVNPDNCVS------HQCQNGGTCQDG 296
Query: 388 VGGYVCQCLGGYTRKDKFNCVE-VDECE--GNTHGCHADAVCTNTPGSYTCRCRDGYEGD 444
+ Y C C +T D C E VDECE G H C C N+ GS+ C C G+ G
Sbjct: 297 LDTYTCLCPETWTGWD---CSEDVDECEAQGPPH-CRNGGTCQNSAGSFHCVCVSGWGGT 352
Query: 445 GYTCMHVDECTEGSHTCHHSARCVNIDGGFRCECFTENCELSCSWQGRVVSE 496
++D+C TC + C++ G F C C L C + +S+
Sbjct: 353 SCE-ENLDDCIAA--TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ 401
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/262 (25%), Positives = 100/262 (38%), Gaps = 29/262 (11%)
Query: 187 GAEARISRLEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEITCRPV--ECDRAEC- 243
G + LE + C+ + + T C C + TC EC A+
Sbjct: 386 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLC-LCQPGYSGPTCHQDLDECLMAQQG 444
Query: 244 KNPVLHPGECCPTCLRQCLLWGNLYEHGERFAP-KECAECVCHDGNMQCTRVDPELACPR 302
+P H G C T L Y A EC CH G+ C + LA
Sbjct: 445 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST-CLDL---LATFH 500
Query: 303 LPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQ 362
C P + G+ C+ + C C +A C +L + C C GF G +
Sbjct: 501 CLCPP----GLEGQLCEV--ETNECASA-PCLNHADCHDLLNGFQCICLPGFSGTRCE-E 552
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCH 421
D+DEC+ + C + +C + G + C+CL G+ C EVDEC + C
Sbjct: 553 DIDECRSSP------CANGGQCQDQPGAFHCKCLPGFEGP---RCQTEVDECLSDP--CP 601
Query: 422 ADAVCTNTPGSYTCRCRDGYEG 443
A C + PG++ C C G+ G
Sbjct: 602 VGASCLDLPGAFFCLCPSGFTG 623
Score = 58.0 bits (134), Expect = 1e-07
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 16/190 (8%)
Query: 301 PRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLT 360
P++ C P F G C+ + + G C + +C N + C C G +G
Sbjct: 178 PQIQCHCPPGFE--GHACERDVNECFQDPG-PCPKGTSCHNTLGSFQCLCPVGQEGPRCE 234
Query: 361 CQDVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHG 419
+ C G +G C + ++C C G+ D C V D C +H
Sbjct: 235 LR-AGPCPPRGCSNGGTCQLMPEKDSTF--HLCLCPPGFIGPD---CEVNPDNCV--SHQ 286
Query: 420 CHADAVCTNTPGSYTCRCRDGYEGDGYTCMH-VDEC-TEGSHTCHHSARCVNIDGGFRCE 477
C C + +YTC C + + G + C VDEC +G C + C N G F C
Sbjct: 287 CQNGGTCQDGLDTYTCLCPETWTG--WDCSEDVDECEAQGPPHCRNGGTCQNSAGSFHCV 344
Query: 478 CFTENCELSC 487
C + SC
Sbjct: 345 CVSGWGGTSC 354
Score = 39.1 bits (87), Expect = 0.048
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 333 CDENATC-MNLNTKYTCKCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRCVNVVGGY 391
C + C + + + C C G+ G+ CQ D C + C + C+
Sbjct: 129 CSKRGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCS------ANPCVNGGVCLATYPQI 180
Query: 392 VCQCLGGYTRKDKFNCV-EVDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEG 443
C C G+ + C +V+EC + C C NT GS+ C C G EG
Sbjct: 181 QCHCPPGF---EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEG 230
>AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein.
Length = 723
Score = 86.2 bits (204), Expect = 3e-16
Identities = 69/238 (28%), Positives = 95/238 (39%), Gaps = 23/238 (9%)
Query: 247 VLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCD 306
V +PG P C L G +HG P EC V G C C C
Sbjct: 211 VCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRY-CDECIRYPGCLHGTCQ 269
Query: 307 PPQQFSVP-GECCKFC-PGVDYCNMGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQ- 362
P Q + G FC ++YC C ATC N YTC C G+ G TC+
Sbjct: 270 QPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG--ATCEL 327
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
+DEC + C + C ++ Y C C G+ K E+ C
Sbjct: 328 GIDECDPSP------CKNGGSCTDLENSYSCTCPPGFYGK----ICELSAMTCADGPCFN 377
Query: 423 DAVCTNTP-GSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+++P G Y+CRC GY G + C +D C+ S C + A+CV++ + C C
Sbjct: 378 GGRCSDSPDGGYSCRCPVGYSG--FNCEKKIDYCS--SSPCSNGAKCVDLGDAYLCRC 431
Score = 70.9 bits (166), Expect = 1e-11
Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 38/256 (14%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEI--TCRPV--ECDRAECKNPVLHP 250
L C K C + T G + CSC G TC ECD + CKN
Sbjct: 289 LNYCTHHKPCKNGATCTNTG----QGSYTCSCRPGYTGATCELGIDECDPSPCKNG---- 340
Query: 251 GECCPT-CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
G C C Y + CA+ C +G D +C C P
Sbjct: 341 GSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR---C--PV 395
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQ 368
+S G C+ +DYC+ C A C++L Y C+C GF G C D VD+C
Sbjct: 396 GYS--GFNCE--KKIDYCSSS-PCSNGAKCVDLGDAYLCRCQAGF--SGRHCDDNVDDCA 448
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCT 427
+ C + C + V + C C GYT + NC V CE CH A C
Sbjct: 449 SS------PCANGGTCRDGVNDFSCTCPPGYTGR---NCSAPVSRCEHAP--CHNGATCH 497
Query: 428 NTPGSYTCRCRDGYEG 443
Y C C GY G
Sbjct: 498 ERGHRYVCECARGYGG 513
Score = 61.3 bits (142), Expect = 1e-08
Identities = 49/203 (24%), Positives = 82/203 (40%), Gaps = 28/203 (13%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
EC C +G CT ++ +C C PP + E C G C ++
Sbjct: 331 ECDPSPCKNGG-SCTDLENSYSCT---C-PPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
+ Y+C+C G+ G C+ +D C + C + +CV++ Y+C+C
Sbjct: 386 -----DGGYSCRCPVGYSG--FNCEKKIDYCSSSP------CSNGAKCVDLGDAYLCRCQ 432
Query: 397 GGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G++ + +C + VD+C + C C + ++C C GY G + V C
Sbjct: 433 AGFSGR---HCDDNVDDCASSP--CANGGTCRDGVNDFSCTCPPGYTGRNCSAP-VSRCE 486
Query: 456 EGSHTCHHSARCVNIDGGFRCEC 478
CH+ A C + CEC
Sbjct: 487 HAP--CHNGATCHERGHRYVCEC 507
>AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophila)
protein.
Length = 723
Score = 86.2 bits (204), Expect = 3e-16
Identities = 69/238 (28%), Positives = 95/238 (39%), Gaps = 23/238 (9%)
Query: 247 VLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCD 306
V +PG P C L G +HG P EC V G C C C
Sbjct: 211 VCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRY-CDECIRYPGCLHGTCQ 269
Query: 307 PPQQFSVP-GECCKFC-PGVDYCNMGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQ- 362
P Q + G FC ++YC C ATC N YTC C G+ G TC+
Sbjct: 270 QPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG--ATCEL 327
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
+DEC + C + C ++ Y C C G+ K E+ C
Sbjct: 328 GIDECDPSP------CKNGGSCTDLENSYSCTCPPGFYGK----ICELSAMTCADGPCFN 377
Query: 423 DAVCTNTP-GSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+++P G Y+CRC GY G + C +D C+ S C + A+CV++ + C C
Sbjct: 378 GGRCSDSPDGGYSCRCPVGYSG--FNCEKKIDYCS--SSPCSNGAKCVDLGDAYLCRC 431
Score = 70.9 bits (166), Expect = 1e-11
Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 38/256 (14%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEI--TCRPV--ECDRAECKNPVLHP 250
L C K C + T G + CSC G TC ECD + CKN
Sbjct: 289 LNYCTHHKPCKNGATCTNTG----QGSYTCSCRPGYTGATCELGIDECDPSPCKNG---- 340
Query: 251 GECCPT-CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
G C C Y + CA+ C +G D +C C P
Sbjct: 341 GSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR---C--PV 395
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQ 368
+S G C+ +DYC+ C A C++L Y C+C GF G C D VD+C
Sbjct: 396 GYS--GFNCE--KKIDYCSSS-PCSNGAKCVDLGDAYLCRCQAGF--SGRHCDDNVDDCA 448
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCT 427
+ C + C + V + C C GYT + NC V CE CH A C
Sbjct: 449 SS------PCANGGTCRDGVNDFSCTCPPGYTGR---NCSAPVSRCEHAP--CHNGATCH 497
Query: 428 NTPGSYTCRCRDGYEG 443
Y C C GY G
Sbjct: 498 ERGHRYVCECARGYGG 513
Score = 61.3 bits (142), Expect = 1e-08
Identities = 49/203 (24%), Positives = 82/203 (40%), Gaps = 28/203 (13%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
EC C +G CT ++ +C C PP + E C G C ++
Sbjct: 331 ECDPSPCKNGG-SCTDLENSYSCT---C-PPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
+ Y+C+C G+ G C+ +D C + C + +CV++ Y+C+C
Sbjct: 386 -----DGGYSCRCPVGYSG--FNCEKKIDYCSSSP------CSNGAKCVDLGDAYLCRCQ 432
Query: 397 GGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G++ + +C + VD+C + C C + ++C C GY G + V C
Sbjct: 433 AGFSGR---HCDDNVDDCASSP--CANGGTCRDGVNDFSCTCPPGYTGRNCSAP-VSRCE 486
Query: 456 EGSHTCHHSARCVNIDGGFRCEC 478
CH+ A C + CEC
Sbjct: 487 HAP--CHNGATCHERGHRYVCEC 507
>AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein.
Length = 723
Score = 86.2 bits (204), Expect = 3e-16
Identities = 69/238 (28%), Positives = 95/238 (39%), Gaps = 23/238 (9%)
Query: 247 VLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCD 306
V +PG P C L G +HG P EC V G C C C
Sbjct: 211 VCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRY-CDECIRYPGCLHGTCQ 269
Query: 307 PPQQFSVP-GECCKFC-PGVDYCNMGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQ- 362
P Q + G FC ++YC C ATC N YTC C G+ G TC+
Sbjct: 270 QPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG--ATCEL 327
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
+DEC + C + C ++ Y C C G+ K E+ C
Sbjct: 328 GIDECDPSP------CKNGGSCTDLENSYSCTCPPGFYGK----ICELSAMTCADGPCFN 377
Query: 423 DAVCTNTP-GSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+++P G Y+CRC GY G + C +D C+ S C + A+CV++ + C C
Sbjct: 378 GGRCSDSPDGGYSCRCPVGYSG--FNCEKKIDYCS--SSPCSNGAKCVDLGDAYLCRC 431
Score = 71.3 bits (167), Expect = 1e-11
Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 38/256 (14%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEI--TCRPV--ECDRAECKNPVLHP 250
L C K C + T G + CSC G TC ECD + CKN
Sbjct: 289 LNYCTHHKPCKNGATCTNTG----QGSYTCSCRPGYTGATCELGIDECDPSPCKNG---- 340
Query: 251 GECCPT-CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
G C C Y + CA+ C +G D +C C P
Sbjct: 341 GSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR---C--PV 395
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQ 368
+S G C+ +DYC+ C A C++L Y C+C GF G C D VD+C
Sbjct: 396 GYS--GFNCE--KKIDYCSSS-PCSNGAKCVDLGDAYLCRCQAGF--SGRHCDDNVDDCA 448
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCT 427
+ C + C + V + C C GYT + NC V CE CH A C
Sbjct: 449 SS------PCANGGTCRDGVNDFSCTCPPGYTGR---NCSAPVSRCEHAP--CHNGATCH 497
Query: 428 NTPGSYTCRCRDGYEG 443
Y C C GY G
Sbjct: 498 ERGHGYVCECARGYGG 513
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/203 (24%), Positives = 83/203 (40%), Gaps = 28/203 (13%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
EC C +G CT ++ +C C PP + E C G C ++
Sbjct: 331 ECDPSPCKNGG-SCTDLENSYSCT---C-PPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
+ Y+C+C G+ G C+ +D C + C + +CV++ Y+C+C
Sbjct: 386 -----DGGYSCRCPVGYSG--FNCEKKIDYCSSSP------CSNGAKCVDLGDAYLCRCQ 432
Query: 397 GGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G++ + +C + VD+C + C C + ++C C GY G + V C
Sbjct: 433 AGFSGR---HCDDNVDDCASSP--CANGGTCRDGVNDFSCTCPPGYTGRNCSAP-VSRCE 486
Query: 456 EGSHTCHHSARCVNIDGGFRCEC 478
CH+ A C G+ CEC
Sbjct: 487 HAP--CHNGATCHERGHGYVCEC 507
>AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein
protein.
Length = 723
Score = 86.2 bits (204), Expect = 3e-16
Identities = 69/238 (28%), Positives = 95/238 (39%), Gaps = 23/238 (9%)
Query: 247 VLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCD 306
V +PG P C L G +HG P EC V G C C C
Sbjct: 211 VCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRY-CDECIRYPGCLHGTCQ 269
Query: 307 PPQQFSVP-GECCKFC-PGVDYCNMGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQ- 362
P Q + G FC ++YC C ATC N YTC C G+ G TC+
Sbjct: 270 QPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG--ATCEL 327
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
+DEC + C + C ++ Y C C G+ K E+ C
Sbjct: 328 GIDECDPSP------CKNGGSCTDLENSYSCTCPPGFYGK----ICELSAMTCADGPCFN 377
Query: 423 DAVCTNTP-GSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+++P G Y+CRC GY G + C +D C+ S C + A+CV++ + C C
Sbjct: 378 GGRCSDSPDGGYSCRCPVGYSG--FNCEKKIDYCS--SSPCSNGAKCVDLGDAYLCRC 431
Score = 68.9 bits (161), Expect = 5e-11
Identities = 73/256 (28%), Positives = 93/256 (36%), Gaps = 38/256 (14%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEI--TCRPV--ECDRAECKNPVLHP 250
L C K C + T G + CSC G TC ECD + CKN
Sbjct: 289 LNYCTHHKPCKNGATCTNTG----QGSYTCSCRPGYTGATCELGIDECDPSPCKNG---- 340
Query: 251 GECCPT-CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
G C C Y + CA+ C +G D +C C P
Sbjct: 341 GSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR---C--PV 395
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQ 368
+S G C+ +DYC+ C A C++L Y C+C GF G C D VD+C
Sbjct: 396 GYS--GFNCE--KKIDYCSSS-PCSNGAKCVDLGDAYLCRCQAGF--SGRHCDDNVDDCA 448
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCT 427
+ C + C + V + C C GYT + NC V CE CH A C
Sbjct: 449 SS------PCANGGTCRDGVNDFSCTCPPGYTGR---NCSAPVSRCEHAP--CHNGATCH 497
Query: 428 NTPGSYTCRCRDGYEG 443
Y C C Y G
Sbjct: 498 QRGHGYVCECARSYGG 513
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/203 (24%), Positives = 83/203 (40%), Gaps = 28/203 (13%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
EC C +G CT ++ +C C PP + E C G C ++
Sbjct: 331 ECDPSPCKNGG-SCTDLENSYSCT---C-PPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
+ Y+C+C G+ G C+ +D C + C + +CV++ Y+C+C
Sbjct: 386 -----DGGYSCRCPVGYSG--FNCEKKIDYCSSSP------CSNGAKCVDLGDAYLCRCQ 432
Query: 397 GGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G++ + +C + VD+C + C C + ++C C GY G + V C
Sbjct: 433 AGFSGR---HCDDNVDDCASSP--CANGGTCRDGVNDFSCTCPPGYTGRNCSAP-VSRCE 486
Query: 456 EGSHTCHHSARCVNIDGGFRCEC 478
CH+ A C G+ CEC
Sbjct: 487 HAP--CHNGATCHQRGHGYVCEC 507
>AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein.
Length = 723
Score = 86.2 bits (204), Expect = 3e-16
Identities = 69/238 (28%), Positives = 95/238 (39%), Gaps = 23/238 (9%)
Query: 247 VLHPGECCPTCLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCD 306
V +PG P C L G +HG P EC V G C C C
Sbjct: 211 VCNPGWKGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRY-CDECIRYPGCLHGTCQ 269
Query: 307 PPQQFSVP-GECCKFC-PGVDYCNMGHSCDENATCMNLNT-KYTCKCNQGFQGDGLTCQ- 362
P Q + G FC ++YC C ATC N YTC C G+ G TC+
Sbjct: 270 QPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG--ATCEL 327
Query: 363 DVDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNCVEVDECEGNTHGCHA 422
+DEC + C + C ++ Y C C G+ K E+ C
Sbjct: 328 GIDECDPSP------CKNGGSCTDLENSYSCTCPPGFYGK----ICELSAMTCADGPCFN 377
Query: 423 DAVCTNTP-GSYTCRCRDGYEGDGYTC-MHVDECTEGSHTCHHSARCVNIDGGFRCEC 478
C+++P G Y+CRC GY G + C +D C+ S C + A+CV++ + C C
Sbjct: 378 GGRCSDSPDGGYSCRCPVGYSG--FNCEKKIDYCS--SSPCSNGAKCVDLGDAYLCRC 431
Score = 71.3 bits (167), Expect = 1e-11
Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 38/256 (14%)
Query: 195 LEQCDCQKSCYSNGTVHADGATWQRDCNRCSCVHGEI--TCRPV--ECDRAECKNPVLHP 250
L C K C + T G + CSC G TC ECD + CKN
Sbjct: 289 LNYCTHHKPCKNGATCTNTG----QGSYTCSCRPGYTGATCELGIDECDPSPCKNG---- 340
Query: 251 GECCPT-CLRQCLLWGNLYEHGERFAPKECAECVCHDGNMQCTRVDPELACPRLPCDPPQ 309
G C C Y + CA+ C +G D +C C P
Sbjct: 341 GSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCR---C--PV 395
Query: 310 QFSVPGECCKFCPGVDYCNMGHSCDENATCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQ 368
+S G C+ +DYC+ C A C++L Y C+C GF G C D VD+C
Sbjct: 396 GYS--GFNCE--KKIDYCSSS-PCSNGAKCVDLGDAYLCRCQAGF--SGRHCDDNVDDCA 448
Query: 369 EAGGLHGHHCHSNTRCVNVVGGYVCQCLGGYTRKDKFNC-VEVDECEGNTHGCHADAVCT 427
+ C + C + V + C C GYT + NC V CE CH A C
Sbjct: 449 SS------PCANGGTCRDGVNDFSCTCPPGYTGR---NCSAPVSRCEHAP--CHNGATCH 497
Query: 428 NTPGSYTCRCRDGYEG 443
Y C C GY G
Sbjct: 498 ERGHGYVCECARGYGG 513
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/203 (24%), Positives = 83/203 (40%), Gaps = 28/203 (13%)
Query: 278 ECAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENA 337
EC C +G CT ++ +C C PP + E C G C ++
Sbjct: 331 ECDPSPCKNGG-SCTDLENSYSCT---C-PPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Query: 338 TCMNLNTKYTCKCNQGFQGDGLTCQD-VDECQEAGGLHGHHCHSNTRCVNVVGGYVCQCL 396
+ Y+C+C G+ G C+ +D C + C + +CV++ Y+C+C
Sbjct: 386 -----DGGYSCRCPVGYSG--FNCEKKIDYCSSSP------CSNGAKCVDLGDAYLCRCQ 432
Query: 397 GGYTRKDKFNCVE-VDECEGNTHGCHADAVCTNTPGSYTCRCRDGYEGDGYTCMHVDECT 455
G++ + +C + VD+C + C C + ++C C GY G + V C
Sbjct: 433 AGFSGR---HCDDNVDDCASSP--CANGGTCRDGVNDFSCTCPPGYTGRNCSAP-VSRCE 486
Query: 456 EGSHTCHHSARCVNIDGGFRCEC 478
CH+ A C G+ CEC
Sbjct: 487 HAP--CHNGATCHERGHGYVCEC 507
>BC125092-1|AAI25093.1| 757|Homo sapiens cartilage oligomeric
matrix protein protein.
Length = 757
Score = 85.4 bits (202), Expect = 6e-16
Identities = 56/173 (32%), Positives = 80/173 (46%), Gaps = 27/173 (15%)
Query: 326 YCNMGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
+C G C C+ + C C GF G+G C DV+EC + H C RC
Sbjct: 90 HCAPGF-CFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNEC------NAHPCFPRVRC 142
Query: 385 VNVVGGYVCQ-CLGGYT------------RKDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+N G+ C+ C GY+ + +K C +++ECE H C ++VC NT G
Sbjct: 143 INTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRG 202
Query: 432 SYTC-RCRDGYEGDGYT-CMHVDE--CTEGSHT-CHHSARCV-NIDGGFRCEC 478
S+ C C+ G+ GD + C + C +GS + CH A CV DG C C
Sbjct: 203 SFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVC 255
Score = 64.5 bits (150), Expect = 1e-09
Identities = 56/189 (29%), Positives = 79/189 (41%), Gaps = 32/189 (16%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA C G + C + + C PC P F+ G C V+ CN H C
Sbjct: 91 CAPGFCFPG-VACIQTESGARCG--PC--PAGFTGNGS---HCTDVNECN-AHPCFPRVR 141
Query: 339 CMNLNTKYTCK-CNQGF-----QGDGLT--------CQDVDECQEAGGLHGHHCHSNTRC 384
C+N + + C+ C G+ QG GL C D++EC E G H+C N+ C
Sbjct: 142 CINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINEC-ETGQ---HNCVPNSVC 197
Query: 385 VNVVGGYVC-QCLGGYTRKDKFNCVEVDE--C-EGNTHGCHADAVCT-NTPGSYTCRCRD 439
+N G + C C G+ C + C +G+ CH A C GS +C C
Sbjct: 198 INTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
Query: 440 GYEGDGYTC 448
G+ G+G C
Sbjct: 258 GWAGNGILC 266
>BC110847-1|AAI10848.1| 757|Homo sapiens cartilage oligomeric
matrix protein protein.
Length = 757
Score = 85.4 bits (202), Expect = 6e-16
Identities = 56/173 (32%), Positives = 80/173 (46%), Gaps = 27/173 (15%)
Query: 326 YCNMGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
+C G C C+ + C C GF G+G C DV+EC + H C RC
Sbjct: 90 HCAPGF-CFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNEC------NAHPCFPRVRC 142
Query: 385 VNVVGGYVCQ-CLGGYT------------RKDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+N G+ C+ C GY+ + +K C +++ECE H C ++VC NT G
Sbjct: 143 INTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRG 202
Query: 432 SYTC-RCRDGYEGDGYT-CMHVDE--CTEGSHT-CHHSARCV-NIDGGFRCEC 478
S+ C C+ G+ GD + C + C +GS + CH A CV DG C C
Sbjct: 203 SFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVC 255
Score = 64.5 bits (150), Expect = 1e-09
Identities = 56/189 (29%), Positives = 79/189 (41%), Gaps = 32/189 (16%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA C G + C + + C PC P F+ G C V+ CN H C
Sbjct: 91 CAPGFCFPG-VACIQTESGARCG--PC--PAGFTGNGS---HCTDVNECN-AHPCFPRVR 141
Query: 339 CMNLNTKYTCK-CNQGF-----QGDGLT--------CQDVDECQEAGGLHGHHCHSNTRC 384
C+N + + C+ C G+ QG GL C D++EC E G H+C N+ C
Sbjct: 142 CINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINEC-ETGQ---HNCVPNSVC 197
Query: 385 VNVVGGYVC-QCLGGYTRKDKFNCVEVDE--C-EGNTHGCHADAVCT-NTPGSYTCRCRD 439
+N G + C C G+ C + C +G+ CH A C GS +C C
Sbjct: 198 INTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
Query: 440 GYEGDGYTC 448
G+ G+G C
Sbjct: 258 GWAGNGILC 266
>AC003107-1|AAB86501.1| 817|Homo sapiens COMP_HUMAN protein.
Length = 817
Score = 85.4 bits (202), Expect = 6e-16
Identities = 56/173 (32%), Positives = 80/173 (46%), Gaps = 27/173 (15%)
Query: 326 YCNMGHSCDENATCMNLNTKYTC-KCNQGFQGDGLTCQDVDECQEAGGLHGHHCHSNTRC 384
+C G C C+ + C C GF G+G C DV+EC + H C RC
Sbjct: 90 HCAPGF-CFPGVACIQTESGARCGPCPAGFTGNGSHCTDVNEC------NAHPCFPRVRC 142
Query: 385 VNVVGGYVCQ-CLGGYT------------RKDKFNCVEVDECEGNTHGCHADAVCTNTPG 431
+N G+ C+ C GY+ + +K C +++ECE H C ++VC NT G
Sbjct: 143 INTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINTRG 202
Query: 432 SYTC-RCRDGYEGDGYT-CMHVDE--CTEGSHT-CHHSARCV-NIDGGFRCEC 478
S+ C C+ G+ GD + C + C +GS + CH A CV DG C C
Sbjct: 203 SFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVC 255
Score = 64.5 bits (150), Expect = 1e-09
Identities = 56/189 (29%), Positives = 79/189 (41%), Gaps = 32/189 (16%)
Query: 279 CAECVCHDGNMQCTRVDPELACPRLPCDPPQQFSVPGECCKFCPGVDYCNMGHSCDENAT 338
CA C G + C + + C PC P F+ G C V+ CN H C
Sbjct: 91 CAPGFCFPG-VACIQTESGARCG--PC--PAGFTGNGS---HCTDVNECN-AHPCFPRVR 141
Query: 339 CMNLNTKYTCK-CNQGF-----QGDGLT--------CQDVDECQEAGGLHGHHCHSNTRC 384
C+N + + C+ C G+ QG GL C D++EC E G H+C N+ C
Sbjct: 142 CINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINEC-ETGQ---HNCVPNSVC 197
Query: 385 VNVVGGYVC-QCLGGYTRKDKFNCVEVDE--C-EGNTHGCHADAVCT-NTPGSYTCRCRD 439
+N G + C C G+ C + C +G+ CH A C GS +C C
Sbjct: 198 INTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAV 257
Query: 440 GYEGDGYTC 448
G+ G+G C
Sbjct: 258 GWAGNGILC 266
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.324 0.138 0.485
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,699,693
Number of Sequences: 224733
Number of extensions: 4879286
Number of successful extensions: 32553
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 655
Number of HSP's successfully gapped in prelim test: 628
Number of HSP's that attempted gapping in prelim test: 13479
Number of HSP's gapped (non-prelim): 7167
length of query: 654
length of database: 73,234,838
effective HSP length: 95
effective length of query: 559
effective length of database: 51,885,203
effective search space: 29003828477
effective search space used: 29003828477
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.5 bits)
S2: 68 (31.5 bits)
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