Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA001102-TA|BGIBMGA001102-PA|IPR013234|PIGA, GPI anchor
biosynthesis, IPR001296|Glycosyl transferase, group 1
(431 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D28791-1|BAA05966.1| 484|Homo sapiens PIG-A protein protein. 485 e-137
D11466-1|BAA02019.1| 484|Homo sapiens PIG-A protein protein. 485 e-137
BC038236-1|AAH38236.1| 484|Homo sapiens phosphatidylinositol gl... 485 e-137
X77725-1|CAB57276.1| 248|Homo sapiens PIG-A protein. 211 3e-54
S74936-1|AAD14160.1| 315|Homo sapiens ria patient LD, periphera... 164 5e-40
S61523-1|AAD13929.1| 51|Homo sapiens PIG-A protein. 52 3e-06
AK056540-1|BAB71209.1| 266|Homo sapiens protein ( Homo sapiens ... 36 0.28
AY281366-1|AAQ16408.1| 458|Homo sapiens glycosyltransferase-lik... 33 2.6
AK021815-1|BAB13904.1| 272|Homo sapiens protein ( Homo sapiens ... 33 2.6
AJ007421-1|CAB65124.1| 1272|Homo sapiens spalt-like zinc finger ... 33 2.6
AF347021-1|AAK18311.1| 1300|Homo sapiens C2H2 zinc finger protei... 33 2.6
AC016910-1|AAY14764.1| 166|Homo sapiens unknown protein. 33 2.6
AB201269-1|BAE16560.1| 458|Homo sapiens mannosyltransferase can... 33 2.6
>D28791-1|BAA05966.1| 484|Homo sapiens PIG-A protein protein.
Length = 484
Score = 485 bits (1197), Expect = e-137
Identities = 223/386 (57%), Positives = 294/386 (76%), Gaps = 1/386 (0%)
Query: 4 RKKRQVVCMASDFFYPNTGGVEEHIFNLSQCLIKRGHKVIVLTHSYGDRVGIRYLTAGLK 63
R + +CM SDFFYPN GGVE HI+ LSQCLI+RGHKVI++TH+YG+R GIRYLT+GLK
Sbjct: 29 RTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLK 88
Query: 64 VYYLPIRVFYAQCVLPTMICNIALIRNILIRECIEIVHGHSAFSVLCHEVCIIGKLMGLK 123
VYYLP++V Y Q T+ ++ L+R I +RE + I+H HS+FS + H+ K MGL+
Sbjct: 89 VYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHDALFHAKTMGLQ 148
Query: 124 TVFTDHSLFGFADTSAVLTNKYLQICLSEIDHCICVSHTGKENTVLRAKVQAHKVSVIPN 183
TVFTDHSLFGFAD S+VLTNK L + L + +H ICVS+T KENTVLRA + VSVIPN
Sbjct: 149 TVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPN 208
Query: 184 AVDAFSFIPDPCQRDQKFITIVIVSRLVYRKGVNLMAAVIADMCPRYPNLRFIIGGDGPK 243
AVD F PDP +R ITIV+VSRLVYRKG++L++ +I ++C +YP+L FIIGG+GPK
Sbjct: 209 AVDPTDFTPDPFRRHDS-ITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPK 267
Query: 244 MWLLQEVREKIGCQESVRLLGSLKHSEIRNVLVKGDIFLNTSLTEAYCMAIVEAAACGLK 303
+L+EVRE+ + VRLLG+L+H ++RNVLV+G IFLNTSLTEA+CMAIVEAA+CGL+
Sbjct: 268 RIILEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQ 327
Query: 304 VVSTKVGGIPEVLPESMIYLTEPNVGSLVRGIEKAITDIKEGNIMCPFKCNRLVREMYSW 363
VVST+VGGIPEVLPE++I L EP+V SL G+EKAI +K G + P + +V+ Y+W
Sbjct: 328 VVSTRVGGIPEVLPENLIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTW 387
Query: 364 MDITKRTEGVYDRILLNKNKPLGQQL 389
++ +RTE VYDR+ + P+ ++L
Sbjct: 388 RNVAERTEKVYDRVSVEAVLPMDKRL 413
>D11466-1|BAA02019.1| 484|Homo sapiens PIG-A protein protein.
Length = 484
Score = 485 bits (1197), Expect = e-137
Identities = 223/386 (57%), Positives = 294/386 (76%), Gaps = 1/386 (0%)
Query: 4 RKKRQVVCMASDFFYPNTGGVEEHIFNLSQCLIKRGHKVIVLTHSYGDRVGIRYLTAGLK 63
R + +CM SDFFYPN GGVE HI+ LSQCLI+RGHKVI++TH+YG+R GIRYLT+GLK
Sbjct: 29 RTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLK 88
Query: 64 VYYLPIRVFYAQCVLPTMICNIALIRNILIRECIEIVHGHSAFSVLCHEVCIIGKLMGLK 123
VYYLP++V Y Q T+ ++ L+R I +RE + I+H HS+FS + H+ K MGL+
Sbjct: 89 VYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHDALFHAKTMGLQ 148
Query: 124 TVFTDHSLFGFADTSAVLTNKYLQICLSEIDHCICVSHTGKENTVLRAKVQAHKVSVIPN 183
TVFTDHSLFGFAD S+VLTNK L + L + +H ICVS+T KENTVLRA + VSVIPN
Sbjct: 149 TVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPN 208
Query: 184 AVDAFSFIPDPCQRDQKFITIVIVSRLVYRKGVNLMAAVIADMCPRYPNLRFIIGGDGPK 243
AVD F PDP +R ITIV+VSRLVYRKG++L++ +I ++C +YP+L FIIGG+GPK
Sbjct: 209 AVDPTDFTPDPFRRHDS-ITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPK 267
Query: 244 MWLLQEVREKIGCQESVRLLGSLKHSEIRNVLVKGDIFLNTSLTEAYCMAIVEAAACGLK 303
+L+EVRE+ + VRLLG+L+H ++RNVLV+G IFLNTSLTEA+CMAIVEAA+CGL+
Sbjct: 268 RIILEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQ 327
Query: 304 VVSTKVGGIPEVLPESMIYLTEPNVGSLVRGIEKAITDIKEGNIMCPFKCNRLVREMYSW 363
VVST+VGGIPEVLPE++I L EP+V SL G+EKAI +K G + P + +V+ Y+W
Sbjct: 328 VVSTRVGGIPEVLPENLIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTW 387
Query: 364 MDITKRTEGVYDRILLNKNKPLGQQL 389
++ +RTE VYDR+ + P+ ++L
Sbjct: 388 RNVAERTEKVYDRVSVEAVLPMDKRL 413
>BC038236-1|AAH38236.1| 484|Homo sapiens phosphatidylinositol
glycan anchor biosynthesis, class A (paroxysmal
nocturnal protein.
Length = 484
Score = 485 bits (1197), Expect = e-137
Identities = 223/386 (57%), Positives = 294/386 (76%), Gaps = 1/386 (0%)
Query: 4 RKKRQVVCMASDFFYPNTGGVEEHIFNLSQCLIKRGHKVIVLTHSYGDRVGIRYLTAGLK 63
R + +CM SDFFYPN GGVE HI+ LSQCLI+RGHKVI++TH+YG+R GIRYLT+GLK
Sbjct: 29 RTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLK 88
Query: 64 VYYLPIRVFYAQCVLPTMICNIALIRNILIRECIEIVHGHSAFSVLCHEVCIIGKLMGLK 123
VYYLP++V Y Q T+ ++ L+R I +RE + I+H HS+FS + H+ K MGL+
Sbjct: 89 VYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHDALFHAKTMGLQ 148
Query: 124 TVFTDHSLFGFADTSAVLTNKYLQICLSEIDHCICVSHTGKENTVLRAKVQAHKVSVIPN 183
TVFTDHSLFGFAD S+VLTNK L + L + +H ICVS+T KENTVLRA + VSVIPN
Sbjct: 149 TVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPN 208
Query: 184 AVDAFSFIPDPCQRDQKFITIVIVSRLVYRKGVNLMAAVIADMCPRYPNLRFIIGGDGPK 243
AVD F PDP +R ITIV+VSRLVYRKG++L++ +I ++C +YP+L FIIGG+GPK
Sbjct: 209 AVDPTDFTPDPFRRHDS-ITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPK 267
Query: 244 MWLLQEVREKIGCQESVRLLGSLKHSEIRNVLVKGDIFLNTSLTEAYCMAIVEAAACGLK 303
+L+EVRE+ + VRLLG+L+H ++RNVLV+G IFLNTSLTEA+CMAIVEAA+CGL+
Sbjct: 268 RIILEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQ 327
Query: 304 VVSTKVGGIPEVLPESMIYLTEPNVGSLVRGIEKAITDIKEGNIMCPFKCNRLVREMYSW 363
VVST+VGGIPEVLPE++I L EP+V SL G+EKAI +K G + P + +V+ Y+W
Sbjct: 328 VVSTRVGGIPEVLPENLIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTW 387
Query: 364 MDITKRTEGVYDRILLNKNKPLGQQL 389
++ +RTE VYDR+ + P+ ++L
Sbjct: 388 RNVAERTEKVYDRVSVEAVLPMDKRL 413
>X77725-1|CAB57276.1| 248|Homo sapiens PIG-A protein.
Length = 248
Score = 211 bits (516), Expect = 3e-54
Identities = 97/185 (52%), Positives = 138/185 (74%), Gaps = 2/185 (1%)
Query: 195 CQRDQKFITIVIVSRLVYRKGV--NLMAAVIADMCPRYPNLRFIIGGDGPKMWLLQEVRE 252
C ++ I++ RKG+ +L++ +I ++C +YP+L FIIGG+GPK +L+EVRE
Sbjct: 59 CLIERGHKVIIVTHAYGNRKGIRIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRE 118
Query: 253 KIGCQESVRLLGSLKHSEIRNVLVKGDIFLNTSLTEAYCMAIVEAAACGLKVVSTKVGGI 312
+ + VRLLG+L+H ++RNVLV+G IFLNTSLTEA+CMAIVEAA+CGL+VVST+VGGI
Sbjct: 119 RYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGI 178
Query: 313 PEVLPESMIYLTEPNVGSLVRGIEKAITDIKEGNIMCPFKCNRLVREMYSWMDITKRTEG 372
PEVLPE++I L EP+V SL G+EKAI +K G + P + +V+ Y+W ++ +RTE
Sbjct: 179 PEVLPENLIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEK 238
Query: 373 VYDRI 377
VYDR+
Sbjct: 239 VYDRV 243
Score = 88.2 bits (209), Expect = 5e-17
Identities = 36/53 (67%), Positives = 44/53 (83%)
Query: 4 RKKRQVVCMASDFFYPNTGGVEEHIFNLSQCLIKRGHKVIVLTHSYGDRVGIR 56
R + +CM SDFFYPN GGVE HI+ LSQCLI+RGHKVI++TH+YG+R GIR
Sbjct: 29 RTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIR 81
>S74936-1|AAD14160.1| 315|Homo sapiens ria patient LD, peripheral
blood protein.
Length = 315
Score = 164 bits (399), Expect = 5e-40
Identities = 75/130 (57%), Positives = 102/130 (78%)
Query: 260 VRLLGSLKHSEIRNVLVKGDIFLNTSLTEAYCMAIVEAAACGLKVVSTKVGGIPEVLPES 319
VRLLG+L+H ++RNVLV+G IFLNTSLTEA+CMAIVEAA+CGL+VVST+VGGIPEVLPE+
Sbjct: 115 VRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLPEN 174
Query: 320 MIYLTEPNVGSLVRGIEKAITDIKEGNIMCPFKCNRLVREMYSWMDITKRTEGVYDRILL 379
+I L EP+V SL G+EKAI +K G + P + +V+ Y+W ++ +RTE VYDR+ +
Sbjct: 175 LIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDRVSV 234
Query: 380 NKNKPLGQQL 389
P+ ++L
Sbjct: 235 EAVLPMDKRL 244
Score = 125 bits (302), Expect = 3e-28
Identities = 53/86 (61%), Positives = 68/86 (79%)
Query: 4 RKKRQVVCMASDFFYPNTGGVEEHIFNLSQCLIKRGHKVIVLTHSYGDRVGIRYLTAGLK 63
R + +CM SDFFYPN GGVE HI+ LSQCLI+RGHKVI++TH+YG+R GIRYLT+GLK
Sbjct: 29 RTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLK 88
Query: 64 VYYLPIRVFYAQCVLPTMICNIALIR 89
VYYLP++V Y Q T+ ++ L+R
Sbjct: 89 VYYLPLKVMYNQSTATTLFHSLPLLR 114
>S61523-1|AAD13929.1| 51|Homo sapiens PIG-A protein.
Length = 51
Score = 52.4 bits (120), Expect = 3e-06
Identities = 23/28 (82%), Positives = 27/28 (96%)
Query: 277 KGDIFLNTSLTEAYCMAIVEAAACGLKV 304
+G IFLNTSLTEA+CMAIVEAA+CGL+V
Sbjct: 1 QGHIFLNTSLTEAFCMAIVEAASCGLQV 28
>AK056540-1|BAB71209.1| 266|Homo sapiens protein ( Homo sapiens
cDNA FLJ31978 fis, clone NT2RP7008406, weakly similar to
Probable hexosyltransferase (EC 2.4.1.-) SC2G5.06. ).
Length = 266
Score = 35.9 bits (79), Expect = 0.28
Identities = 22/94 (23%), Positives = 45/94 (47%)
Query: 248 QEVREKIGCQESVRLLGSLKHSEIRNVLVKGDIFLNTSLTEAYCMAIVEAAACGLKVVST 307
+EV+ K+ VRL+G + ++ V+ +N+S++E AI+EA + V++
Sbjct: 132 REVKAKVKRAAGVRLIGEMPQEDLHAVVKNCFAVVNSSVSEGMSAAILEAMDLEVPVLAR 191
Query: 308 KVGGIPEVLPESMIYLTEPNVGSLVRGIEKAITD 341
+ G V+ + L N V ++ ++D
Sbjct: 192 NIPGNAAVVKHEVTGLLFSNPQEFVHLAKRLVSD 225
>AY281366-1|AAQ16408.1| 458|Homo sapiens glycosyltransferase-like 1
protein.
Length = 458
Score = 32.7 bits (71), Expect = 2.6
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 274 VLVKGDIFLNTSLTEAYCMAIVEAAACGLKVVSTKVGGIPEVLPESMIYLT 324
VL D+ ++T+ E + +A++EA CG + K PE+ P +Y T
Sbjct: 357 VLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYST 407
>AK021815-1|BAB13904.1| 272|Homo sapiens protein ( Homo sapiens
cDNA FLJ11753 fis, clone HEMBA1005583. ).
Length = 272
Score = 32.7 bits (71), Expect = 2.6
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 274 VLVKGDIFLNTSLTEAYCMAIVEAAACGLKVVSTKVGGIPEVLPESMIYLT 324
VL D+ ++T+ E + +A++EA CG + K PE+ P +Y T
Sbjct: 171 VLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYST 221
>AJ007421-1|CAB65124.1| 1272|Homo sapiens spalt-like zinc finger
protein protein.
Length = 1272
Score = 32.7 bits (71), Expect = 2.6
Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Query: 241 GPKMWLLQEVRE--KIGCQESVRLLG--SLKHSEI-RNVLVKGDIFLNTSLTEAYCMAIV 295
G MW R ++ + + LLG +LK SE+ + L + ++ S Y AI
Sbjct: 1133 GTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNVDPSFWNQYAAAIT 1192
Query: 296 EAAACGLKVVST-KVGGIPEVLPESMIYLTEPNVGSLVRGIEKAIT 340
A +S + GGIP+ LP S+ P +GS+ G++KA T
Sbjct: 1193 NGLAMKNNEISVIQNGGIPQ-LPVSLGGSALPPLGSMASGMDKART 1237
>AF347021-1|AAK18311.1| 1300|Homo sapiens C2H2 zinc finger protein
protein.
Length = 1300
Score = 32.7 bits (71), Expect = 2.6
Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Query: 241 GPKMWLLQEVRE--KIGCQESVRLLG--SLKHSEI-RNVLVKGDIFLNTSLTEAYCMAIV 295
G MW R ++ + + LLG +LK SE+ + L + ++ S Y AI
Sbjct: 1161 GTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNVDPSFWNQYAAAIT 1220
Query: 296 EAAACGLKVVST-KVGGIPEVLPESMIYLTEPNVGSLVRGIEKAIT 340
A +S + GGIP+ LP S+ P +GS+ G++KA T
Sbjct: 1221 NGLAMKNNEISVIQNGGIPQ-LPVSLGGSALPPLGSMASGMDKART 1265
>AC016910-1|AAY14764.1| 166|Homo sapiens unknown protein.
Length = 166
Score = 32.7 bits (71), Expect = 2.6
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 274 VLVKGDIFLNTSLTEAYCMAIVEAAACGLKVVSTKVGGIPEVLPESMIYLT 324
VL D+ ++T+ E + +A++EA CG + K PE+ P +Y T
Sbjct: 65 VLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYST 115
>AB201269-1|BAE16560.1| 458|Homo sapiens mannosyltransferase
candidate protein.
Length = 458
Score = 32.7 bits (71), Expect = 2.6
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 274 VLVKGDIFLNTSLTEAYCMAIVEAAACGLKVVSTKVGGIPEVLPESMIYLT 324
VL D+ ++T+ E + +A++EA CG + K PE+ P +Y T
Sbjct: 357 VLCMADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYST 407
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.327 0.142 0.431
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 60,165,726
Number of Sequences: 224733
Number of extensions: 2396476
Number of successful extensions: 4532
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 4516
Number of HSP's gapped (non-prelim): 15
length of query: 431
length of database: 73,234,838
effective HSP length: 92
effective length of query: 339
effective length of database: 52,559,402
effective search space: 17817637278
effective search space used: 17817637278
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 67 (31.1 bits)
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