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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA001100-TA|BGIBMGA001100-PA|IPR000980|SH2 motif,
IPR000242|Tyrosine specific protein phosphatase, IPR000387|Tyrosine
specific protein phosphatase and dual specificity protein phosphatase,
IPR003595|Protein tyrosine phosphatase, catalytic region
         (598 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q16YG8 Cluster: Protein tyrosine phosphatase n11; n=2; ...   416   e-114
UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;...   260   8e-68
UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept...   253   9e-66
UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no...   243   9e-63
UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept...   238   3e-61
UniRef50_Q9NL10 Cluster: AmPTPN6 protein; n=3; Coelomata|Rep: Am...   219   2e-55
UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty...   215   3e-54
UniRef50_Q9Y1W9 Cluster: SPTPN6; n=1; Ephydatia fluviatilis|Rep:...   208   4e-52
UniRef50_Q9NKZ9 Cluster: HgPTPN6b protein; n=1; Eptatretus burge...   169   2e-40
UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ...   164   7e-39
UniRef50_UPI0000E46C41 Cluster: PREDICTED: similar to the murine...   159   3e-37
UniRef50_Q12913 Cluster: Receptor-type tyrosine-protein phosphat...   158   4e-37
UniRef50_A7SQN6 Cluster: Predicted protein; n=2; Nematostella ve...   157   6e-37
UniRef50_A7SWW8 Cluster: Predicted protein; n=1; Nematostella ve...   155   2e-36
UniRef50_A7RTS6 Cluster: Predicted protein; n=1; Nematostella ve...   154   7e-36
UniRef50_Q4RV19 Cluster: Chromosome 15 SCAF14992, whole genome s...   152   2e-35
UniRef50_O14522 Cluster: Receptor-type tyrosine-protein phosphat...   152   2e-35
UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphat...   152   2e-35
UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphat...   152   3e-35
UniRef50_Q4SAP1 Cluster: Chromosome undetermined SCAF14681, whol...   151   4e-35
UniRef50_UPI0000DB76E9 Cluster: PREDICTED: similar to protein ty...   151   5e-35
UniRef50_Q4SFF7 Cluster: Chromosome 1 SCAF14603, whole genome sh...   151   5e-35
UniRef50_UPI0001554856 Cluster: PREDICTED: similar to Tyrosine-p...   151   7e-35
UniRef50_UPI0000E49AED Cluster: PREDICTED: similar to protein ty...   151   7e-35
UniRef50_Q4SH31 Cluster: Chromosome 8 SCAF14587, whole genome sh...   150   9e-35
UniRef50_Q9BI03 Cluster: Receptor protein tyrosine phosphatase; ...   150   9e-35
UniRef50_Q9I8F1 Cluster: CD45 precursor; n=4; Tetraodontidae|Rep...   150   1e-34
UniRef50_UPI0000F1E754 Cluster: PREDICTED: hypothetical protein;...   149   2e-34
UniRef50_O44328 Cluster: Receptor tyrosine phosphatase; n=6; Eum...   149   2e-34
UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor t...   149   3e-34
UniRef50_Q5BJ20 Cluster: Zgc:113105; n=2; Danio rerio|Rep: Zgc:1...   149   3e-34
UniRef50_P23467 Cluster: Receptor-type tyrosine-protein phosphat...   149   3e-34
UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd prot...   148   4e-34
UniRef50_UPI000069DD95 Cluster: Tyrosine-protein phosphatase non...   148   5e-34
UniRef50_A7RS70 Cluster: Predicted protein; n=1; Nematostella ve...   147   6e-34
UniRef50_Q9Y2R2 Cluster: Tyrosine-protein phosphatase non-recept...   147   6e-34
UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella ve...   147   8e-34
UniRef50_Q32NT3 Cluster: MGC52584 protein; n=5; Xenopus|Rep: MGC...   146   1e-33
UniRef50_O44329 Cluster: Receptor tyrosine phosphatase; n=1; Hir...   146   1e-33
UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor ...   146   1e-33
UniRef50_UPI0000F21332 Cluster: PREDICTED: similar to protein ty...   146   2e-33
UniRef50_UPI0000E816EE Cluster: PREDICTED: similar to Tyrosine-p...   146   2e-33
UniRef50_UPI0000DB6DA7 Cluster: PREDICTED: similar to Protein ty...   146   2e-33
UniRef50_Q5W9G3 Cluster: LAR splice variant 1; n=24; Eutheria|Re...   145   3e-33
UniRef50_Q05209 Cluster: Tyrosine-protein phosphatase non-recept...   145   3e-33
UniRef50_Q6E5N7 Cluster: Receptor protein tyrosine phosphatase p...   145   3e-33
UniRef50_Q5C521 Cluster: SJCHGC03800 protein; n=1; Schistosoma j...   145   3e-33
UniRef50_P06800 Cluster: Leukocyte common antigen precursor; n=1...   145   3e-33
UniRef50_Q17N21 Cluster: Protein-tyrosine phosphatase; n=1; Aede...   144   4e-33
UniRef50_A5D6T3 Cluster: Si:dkey-78k11.1 protein; n=3; Danio rer...   144   8e-33
UniRef50_A4QN87 Cluster: LOC569591 protein; n=3; Danio rerio|Rep...   143   1e-32
UniRef50_UPI00015B5CF6 Cluster: PREDICTED: similar to Si:dkey-21...   143   1e-32
UniRef50_UPI00015B5B23 Cluster: PREDICTED: similar to protein-ty...   142   2e-32
UniRef50_UPI000065E288 Cluster: Receptor-type tyrosine-protein p...   142   2e-32
UniRef50_Q91054 Cluster: CD45 homolog; n=1; Heterodontus francis...   142   3e-32
UniRef50_Q4RK94 Cluster: Chromosome 18 SCAF15030, whole genome s...   142   3e-32
UniRef50_A7SDC7 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ...   142   3e-32
UniRef50_P34138 Cluster: Tyrosine-protein phosphatase 2; n=2; Di...   142   3e-32
UniRef50_A7RL98 Cluster: Predicted protein; n=4; Nematostella ve...   141   4e-32
UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar precur...   141   6e-32
UniRef50_Q15426 Cluster: Protein-tyrosine phosphatase receptor t...   140   1e-31
UniRef50_Q9W323 Cluster: CG32697-PA, isoform A; n=5; Drosophila ...   140   1e-31
UniRef50_P18433 Cluster: Receptor-type tyrosine-protein phosphat...   140   1e-31
UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like p...   140   1e-31
UniRef50_UPI00015B4D57 Cluster: PREDICTED: similar to ENSANGP000...   139   2e-31
UniRef50_P35832 Cluster: Tyrosine-protein phosphatase 99A precur...   139   2e-31
UniRef50_Q64512 Cluster: Tyrosine-protein phosphatase non-recept...   139   2e-31
UniRef50_UPI0000F20574 Cluster: PREDICTED: similar to glomerular...   139   2e-31
UniRef50_UPI0000DB795D Cluster: PREDICTED: similar to Protein ty...   139   2e-31
UniRef50_Q4RHI4 Cluster: Chromosome 19 SCAF15047, whole genome s...   139   2e-31
UniRef50_Q12923 Cluster: Tyrosine-protein phosphatase non-recept...   139   2e-31
UniRef50_P08575 Cluster: Leukocyte common antigen precursor; n=1...   139   2e-31
UniRef50_Q179W1 Cluster: Protein-tyrosine phosphatase n9; n=1; A...   138   3e-31
UniRef50_A7SX30 Cluster: Predicted protein; n=7; Nematostella ve...   138   3e-31
UniRef50_UPI000065DD5D Cluster: Homolog of Homo sapiens "protein...   138   5e-31
UniRef50_P35236 Cluster: Tyrosine-protein phosphatase non-recept...   138   5e-31
UniRef50_UPI0000F21610 Cluster: PREDICTED: similar to protein ty...   137   7e-31
UniRef50_P18031 Cluster: Tyrosine-protein phosphatase non-recept...   137   7e-31
UniRef50_UPI0000DB7D47 Cluster: PREDICTED: similar to Tyrosine-p...   136   1e-30
UniRef50_Q6EHH9 Cluster: Frizzled-8 associated multidomain prote...   136   2e-30
UniRef50_UPI000051A95C Cluster: PREDICTED: similar to ia2 CG3179...   136   2e-30
UniRef50_A3KPJ4 Cluster: Protein tyrosine phosphatase, receptor ...   136   2e-30
UniRef50_Q6NSL1 Cluster: PTPRN protein; n=4; Eutheria|Rep: PTPRN...   136   2e-30
UniRef50_Q16849 Cluster: Receptor-type tyrosine-protein phosphat...   136   2e-30
UniRef50_UPI0001554B98 Cluster: PREDICTED: similar to protein ty...   135   3e-30
UniRef50_Q7PWY3 Cluster: ENSANGP00000004166; n=1; Anopheles gamb...   135   4e-30
UniRef50_UPI0000E4935D Cluster: PREDICTED: hypothetical protein;...   134   5e-30
UniRef50_UPI0000519EC5 Cluster: PREDICTED: similar to Tyrosine-p...   134   5e-30
UniRef50_UPI00004D95F8 Cluster: protein tyrosine phosphatase, re...   134   5e-30
UniRef50_Q4SQB7 Cluster: Chromosome 4 SCAF14533, whole genome sh...   134   5e-30
UniRef50_P43378 Cluster: Tyrosine-protein phosphatase non-recept...   134   5e-30
UniRef50_UPI00005A2CD6 Cluster: PREDICTED: similar to Receptor-t...   134   6e-30
UniRef50_A7T4C4 Cluster: Predicted protein; n=1; Nematostella ve...   134   6e-30
UniRef50_P54829 Cluster: Tyrosine-protein phosphatase non-recept...   134   6e-30
UniRef50_UPI0000E4A291 Cluster: PREDICTED: similar to testis-enr...   134   8e-30
UniRef50_UPI0000E494F1 Cluster: PREDICTED: similar to protein-ty...   134   8e-30
UniRef50_UPI000065CBFD Cluster: Tyrosine-protein phosphatase non...   134   8e-30
UniRef50_P23471-2 Cluster: Isoform Short of P23471 ; n=6; Tetrap...   134   8e-30
UniRef50_P23471 Cluster: Receptor-type tyrosine-protein phosphat...   134   8e-30
UniRef50_O55082 Cluster: Tyrosine-protein phosphatase non-recept...   134   8e-30
UniRef50_Q8MY44 Cluster: CD45; n=5; Eptatretus stoutii|Rep: CD45...   133   1e-29
UniRef50_P35992 Cluster: Tyrosine-protein phosphatase 10D precur...   133   1e-29
UniRef50_A0AV39 Cluster: Protein tyrosine phosphatase, receptor ...   133   1e-29
UniRef50_Q16827 Cluster: Receptor-type tyrosine-protein phosphat...   133   1e-29
UniRef50_P35821 Cluster: Tyrosine-protein phosphatase non-recept...   133   1e-29
UniRef50_O01556 Cluster: Putative uncharacterized protein; n=2; ...   132   2e-29
UniRef50_Q5W0Y5 Cluster: Protein tyrosine phosphatase, receptor ...   132   2e-29
UniRef50_Q92932 Cluster: Receptor-type tyrosine-protein phosphat...   132   2e-29
UniRef50_Q4JDL3 Cluster: Tyrosine-protein phosphatase non-recept...   132   2e-29
UniRef50_UPI0000E8189A Cluster: PREDICTED: similar to human phos...   132   3e-29
UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;...   132   3e-29
UniRef50_Q20120 Cluster: Putative uncharacterized protein dep-1;...   132   3e-29
UniRef50_A1ZAB3 Cluster: CG18243-PA; n=2; Sophophora|Rep: CG1824...   132   3e-29
UniRef50_P23470 Cluster: Receptor-type tyrosine-protein phosphat...   132   3e-29
UniRef50_UPI0000D5709F Cluster: PREDICTED: similar to CG31795-PA...   132   3e-29
UniRef50_Q90947 Cluster: Phosphotyrosyl phosphatase; n=5; Tetrap...   132   3e-29
UniRef50_UPI00015B6015 Cluster: PREDICTED: hypothetical protein;...   131   4e-29
UniRef50_UPI0000D567E0 Cluster: PREDICTED: similar to Receptor-t...   131   4e-29
UniRef50_Q7QBG0 Cluster: ENSANGP00000003247; n=3; Culicidae|Rep:...   131   6e-29
UniRef50_Q62656 Cluster: Receptor-type tyrosine-protein phosphat...   131   6e-29
UniRef50_Q15678 Cluster: Tyrosine-protein phosphatase non-recept...   130   8e-29
UniRef50_UPI00015A519A Cluster: Receptor-type tyrosine-protein p...   130   1e-28
UniRef50_Q4D9I2 Cluster: Tyrosine specific protein phosphatase, ...   130   1e-28
UniRef50_UPI0000D56952 Cluster: PREDICTED: similar to CG10975-PA...   130   1e-28
UniRef50_Q9Y1X5 Cluster: SPTPR2B; n=1; Ephydatia fluviatilis|Rep...   130   1e-28
UniRef50_Q15256 Cluster: Receptor-type tyrosine-protein phosphat...   130   1e-28
UniRef50_UPI0000E46DBF Cluster: PREDICTED: similar to non-recept...   129   2e-28
UniRef50_UPI0000EB46AF Cluster: protein tyrosine phosphatase, re...   129   2e-28
UniRef50_Q4SDY5 Cluster: Chromosome 13 SCAF14627, whole genome s...   129   2e-28
UniRef50_P17706 Cluster: Tyrosine-protein phosphatase non-recept...   129   2e-28
UniRef50_UPI000065D195 Cluster: Tyrosine-protein phosphatase non...   128   3e-28
UniRef50_Q24495 Cluster: Receptor protein tyrosine phosphatase; ...   128   3e-28
UniRef50_A7SMI6 Cluster: Predicted protein; n=2; Nematostella ve...   128   3e-28
UniRef50_UPI00006A1133 Cluster: protein tyrosine phosphatase, no...   128   4e-28
UniRef50_UPI00004D876B Cluster: protein tyrosine phosphatase, no...   128   4e-28
UniRef50_UPI0000E4853E Cluster: PREDICTED: similar to Receptor-t...   127   1e-27
UniRef50_UPI0000D578C4 Cluster: PREDICTED: similar to CG10975-PB...   126   1e-27
UniRef50_A6NJM5 Cluster: Uncharacterized protein PTPRN2; n=9; Eu...   126   1e-27
UniRef50_P29074 Cluster: Tyrosine-protein phosphatase non-recept...   126   1e-27
UniRef50_Q4SSV8 Cluster: Chromosome undetermined SCAF14347, whol...   126   2e-27
UniRef50_A7RUW8 Cluster: Predicted protein; n=1; Nematostella ve...   126   2e-27
UniRef50_P70289 Cluster: Receptor-type tyrosine-protein phosphat...   126   2e-27
UniRef50_Q98936 Cluster: Receptor-type tyrosine-protein phosphat...   126   2e-27
UniRef50_Q6IPX8 Cluster: PTPN22 protein; n=5; Catarrhini|Rep: PT...   126   2e-27
UniRef50_Q99952 Cluster: Tyrosine-protein phosphatase non-recept...   126   2e-27
UniRef50_Q4TC72 Cluster: Chromosome undetermined SCAF7048, whole...   125   3e-27
UniRef50_Q4T7R9 Cluster: Chromosome undetermined SCAF8020, whole...   125   3e-27
UniRef50_UPI0000E816A0 Cluster: PREDICTED: similar to protein-ty...   125   4e-27
UniRef50_UPI000069DA70 Cluster: Protein tyrosine phosphatase RQ;...   125   4e-27
UniRef50_Q8AV93 Cluster: CD45 protein tyrosine phosphatase recep...   125   4e-27
UniRef50_Q4SWB8 Cluster: Chromosome undetermined SCAF13636, whol...   125   4e-27
UniRef50_Q9NL16 Cluster: AmPTP10 protein; n=1; Branchiostoma bel...   125   4e-27
UniRef50_A7RLA3 Cluster: Predicted protein; n=1; Nematostella ve...   125   4e-27
UniRef50_A7RJD7 Cluster: Predicted protein; n=1; Nematostella ve...   125   4e-27
UniRef50_Q9UMZ3 Cluster: Phosphotidylinositol phosphatase PTPRQ ...   124   5e-27
UniRef50_UPI000065D738 Cluster: Homolog of Homo sapiens "Splice ...   124   7e-27
UniRef50_UPI0000E45FB8 Cluster: PREDICTED: similar to PTPRT; n=1...   124   9e-27
UniRef50_Q6PNC4 Cluster: Protein tyrosine phosphatase non-recept...   124   9e-27
UniRef50_P16620 Cluster: Tyrosine-protein phosphatase 69D precur...   124   9e-27
UniRef50_UPI0000E4798C Cluster: PREDICTED: similar to phogrin; n...   123   1e-26
UniRef50_Q9NDP4 Cluster: Tyrosine phosphatase; n=1; Ciona intest...   123   1e-26
UniRef50_Q95Y26 Cluster: Putative uncharacterized protein Y41D4A...   122   2e-26
UniRef50_UPI0000E49356 Cluster: PREDICTED: similar to human phos...   121   6e-26
UniRef50_Q7Q404 Cluster: ENSANGP00000010449; n=1; Anopheles gamb...   121   6e-26
UniRef50_UPI000051A879 Cluster: PREDICTED: similar to protein ty...   120   1e-25
UniRef50_UPI0000F2E97C Cluster: PREDICTED: similar to PTPRH prot...   120   1e-25
UniRef50_Q2THU9 Cluster: PTP8; n=3; Bracovirus|Rep: PTP8 - Glypt...   120   1e-25
UniRef50_UPI0000F2AE09 Cluster: PREDICTED: hypothetical protein;...   119   2e-25
UniRef50_Q9W0G1 Cluster: Tyrosine-protein phosphatase non-recept...   119   2e-25
UniRef50_P28191 Cluster: Tyrosine-protein phosphatase 1; n=4; Ca...   119   2e-25
UniRef50_UPI00015B643E Cluster: PREDICTED: similar to ENSANGP000...   118   3e-25
UniRef50_UPI0000D55E2F Cluster: PREDICTED: similar to CG18243-PA...   118   3e-25
UniRef50_Q5BVG2 Cluster: SJCHGC04925 protein; n=2; Schistosoma j...   118   3e-25
UniRef50_UPI0000D56953 Cluster: PREDICTED: similar to Receptor-t...   118   6e-25
UniRef50_UPI00005A3E04 Cluster: PREDICTED: similar to protein ty...   118   6e-25
UniRef50_UPI0000F2E7E7 Cluster: PREDICTED: similar to Tyrosine-p...   117   8e-25
UniRef50_Q3TU63 Cluster: 15 days embryo head cDNA, RIKEN full-le...   117   8e-25
UniRef50_Q69HS3 Cluster: Receptor tyrosine phosphatase-like; n=1...   117   1e-24
UniRef50_Q17JS6 Cluster: Protein tyrosine phosphatase, non-recep...   117   1e-24
UniRef50_A3LZ13 Cluster: Predicted protein; n=3; Saccharomycetal...   117   1e-24
UniRef50_Q9Y1X4 Cluster: SPTPR5; n=1; Ephydatia fluviatilis|Rep:...   116   2e-24
UniRef50_P28192 Cluster: Tyrosine-protein phosphatase 2 precurso...   115   3e-24
UniRef50_Q9Y1X2 Cluster: SPTPN1; n=1; Ephydatia fluviatilis|Rep:...   115   4e-24
UniRef50_O82656 Cluster: Protein tyrosine phosphatase; n=9; core...   114   5e-24
UniRef50_Q9VJ95 Cluster: CG7180-PA; n=8; Endopterygota|Rep: CG71...   114   5e-24
UniRef50_P54637 Cluster: Tyrosine-protein phosphatase 3; n=2; Di...   114   7e-24
UniRef50_Q9Y1W8 Cluster: SPTPN8; n=1; Ephydatia fluviatilis|Rep:...   113   1e-23
UniRef50_UPI0000F203A3 Cluster: PREDICTED: similar to Ptpn23 pro...   112   2e-23
UniRef50_Q9Y1X3 Cluster: SPTPR3; n=1; Ephydatia fluviatilis|Rep:...   112   2e-23
UniRef50_Q9NKZ8 Cluster: HgPTPN3 protein; n=1; Eptatretus burger...   112   3e-23
UniRef50_Q5W3C2 Cluster: Protein tyrosine phosphatase; n=5; Brac...   112   3e-23
UniRef50_Q9NL09 Cluster: AmPTPN3 protein; n=1; Branchiostoma bel...   111   4e-23
UniRef50_UPI0000E45C40 Cluster: PREDICTED: similar to receptor p...   111   5e-23
UniRef50_Q9TZQ1 Cluster: Putative uncharacterized protein; n=5; ...   109   2e-22
UniRef50_UPI000155BF12 Cluster: PREDICTED: similar to protein ty...   108   5e-22
UniRef50_Q4Q0M4 Cluster: Tyrosine specific protein phosphatase, ...   108   5e-22
UniRef50_UPI00006CBB4B Cluster: Protein-tyrosine phosphatase con...   107   6e-22
UniRef50_UPI00006A1AD2 Cluster: Tyrosine-protein phosphatase non...   107   6e-22
UniRef50_Q5I146 Cluster: PTP 2; n=1; Microplitis demolitor braco...   107   6e-22
UniRef50_Q9Y1X0 Cluster: SPTPR7; n=1; Ephydatia fluviatilis|Rep:...   107   6e-22
UniRef50_UPI0000E49995 Cluster: PREDICTED: similar to Receptor-t...   107   1e-21
UniRef50_Q4SQ75 Cluster: Chromosome 2 SCAF14534, whole genome sh...   107   1e-21
UniRef50_Q9NL17 Cluster: AmPTPR3 protein; n=1; Branchiostoma bel...   106   1e-21
UniRef50_A0T008 Cluster: Protein tyrosine phosphatase; n=4; Brac...   105   3e-21
UniRef50_Q22668 Cluster: Putative uncharacterized protein; n=2; ...   105   3e-21
UniRef50_A2PZQ3 Cluster: GfV-B2-ORF1; n=3; Glypta fumiferanae ic...   105   3e-21
UniRef50_Q5AXJ8 Cluster: Putative uncharacterized protein; n=1; ...   105   3e-21
UniRef50_P34137 Cluster: Tyrosine-protein phosphatase 1; n=3; Di...   105   3e-21
UniRef50_Q9Y1X1 Cluster: SPTPN2; n=1; Ephydatia fluviatilis|Rep:...   105   4e-21
UniRef50_Q9H3S7 Cluster: Tyrosine-protein phosphatase non-recept...   105   4e-21
UniRef50_Q1DME1 Cluster: Putative uncharacterized protein; n=1; ...   104   6e-21
UniRef50_A3GI89 Cluster: Protein tyrosine phosphatase; n=1; Pich...   104   6e-21
UniRef50_UPI00015B4244 Cluster: PREDICTED: similar to IP14232p; ...   103   1e-20
UniRef50_A0D1T8 Cluster: Chromosome undetermined scaffold_34, wh...   103   1e-20
UniRef50_UPI0000DB775F Cluster: PREDICTED: similar to CG14714-PA...   103   2e-20
UniRef50_O01557 Cluster: Putative uncharacterized protein; n=3; ...   103   2e-20
UniRef50_Q6BYA8 Cluster: Debaryomyces hansenii chromosome A of s...   103   2e-20
UniRef50_Q2QX07 Cluster: Protein-tyrosine phosphatase containing...   102   2e-20
UniRef50_P91498 Cluster: Putative uncharacterized protein; n=2; ...   102   2e-20
UniRef50_Q4TC71 Cluster: Chromosome undetermined SCAF7048, whole...   102   3e-20
UniRef50_A2PZT3 Cluster: GfV-B36-ORF1; n=1; Glypta fumiferanae i...   102   3e-20
UniRef50_Q8IG13 Cluster: Clear protein 1, isoform b; n=6; Caenor...   102   3e-20
UniRef50_UPI00015603C7 Cluster: PREDICTED: similar to Ptpn21 pro...   101   4e-20
UniRef50_UPI0000E464A3 Cluster: PREDICTED: similar to protein ty...   101   4e-20
UniRef50_P91568 Cluster: Putative uncharacterized protein; n=1; ...   101   4e-20
UniRef50_A5DFA6 Cluster: Putative uncharacterized protein; n=1; ...   101   5e-20
UniRef50_UPI0000E49FA3 Cluster: PREDICTED: similar to RE52018p, ...   100   1e-19
UniRef50_Q5I141 Cluster: PTP 1; n=1; Microplitis demolitor braco...   100   1e-19
UniRef50_A2PZX3 Cluster: GfV-C8-ORF1; n=1; Glypta fumiferanae ic...   100   1e-19
UniRef50_Q966M2 Cluster: Putative uncharacterized protein; n=6; ...   100   1e-19
UniRef50_Q9UDA9 Cluster: Protein-tyrosine phosphatase; n=13; Eut...   100   1e-19
UniRef50_A2Q7J2 Cluster: Contig An01c0050, complete genome; n=1;...   100   1e-19
UniRef50_P32587 Cluster: Tyrosine-protein phosphatase 3; n=1; Sc...   100   1e-19
UniRef50_UPI0000E475CC Cluster: PREDICTED: similar to ENSANGP000...   100   1e-19
UniRef50_A5DI66 Cluster: Putative uncharacterized protein; n=1; ...   100   1e-19
UniRef50_Q6C0H6 Cluster: Similar to tr|Q9P664 Neurospora crassa ...    99   2e-19
UniRef50_P27574 Cluster: Tyrosine-protein phosphatase 1; n=1; Sc...    99   2e-19
UniRef50_A2QDC9 Cluster: Contig An02c0190, complete genome; n=5;...   100   2e-19
UniRef50_Q5W3K6 Cluster: Putative tyrosine phosphatase protein; ...    99   3e-19
UniRef50_Q0MW10 Cluster: Protein tyrosine phosphatase 1; n=4; Br...    99   3e-19
UniRef50_Q61XF0 Cluster: Putative uncharacterized protein CBG040...    99   3e-19
UniRef50_Q0U823 Cluster: Putative uncharacterized protein; n=1; ...    99   3e-19
UniRef50_Q9NL00 Cluster: HgPTPR5b protein; n=1; Eptatretus burge...    99   4e-19
UniRef50_Q4RQG0 Cluster: Chromosome 17 SCAF15006, whole genome s...    99   4e-19
UniRef50_Q5K8S3 Cluster: Protein-tyrosine-phosphatase, putative;...    98   5e-19
UniRef50_UPI000065EB91 Cluster: Homolog of Homo sapiens "Splice ...    97   9e-19
UniRef50_P91345 Cluster: Putative uncharacterized protein; n=3; ...    97   9e-19
UniRef50_Q4EW66 Cluster: Protein tyrosine phosphatase A; n=1; En...    97   1e-18
UniRef50_Q7YZG5 Cluster: Putative uncharacterized protein; n=4; ...    96   3e-18
UniRef50_Q6BEU3 Cluster: Putative uncharacterized protein; n=4; ...    96   3e-18
UniRef50_Q22852 Cluster: Putative uncharacterized protein; n=2; ...    95   6e-18
UniRef50_Q4FEY9 Cluster: Protein tyrosine phosphatase; n=3; Brac...    94   8e-18
UniRef50_Q61WV3 Cluster: Putative uncharacterized protein CBG042...    94   8e-18
UniRef50_Q5ZP01 Cluster: Protein-tyrosine phosphatase; n=2; Brac...    94   1e-17
UniRef50_UPI00006CBB46 Cluster: Protein-tyrosine phosphatase con...    93   2e-17
UniRef50_Q6FPJ8 Cluster: Candida glabrata strain CBS138 chromoso...    92   3e-17
UniRef50_UPI0000D55692 Cluster: PREDICTED: similar to CG14714-PA...    92   4e-17
UniRef50_Q4FEY6 Cluster: Protein tyrosine phosphatase; n=2; Brac...    91   6e-17
UniRef50_A1CKK1 Cluster: Protein-tyrosine phosphatase 2; n=3; Eu...    91   6e-17
UniRef50_UPI000023E225 Cluster: hypothetical protein FG06297.1; ...    91   8e-17
UniRef50_A2PZT9 Cluster: GfV-B43-ORF1; n=1; Glypta fumiferanae i...    91   8e-17
UniRef50_O01435 Cluster: Putative uncharacterized protein; n=1; ...    91   8e-17
UniRef50_A0CMV5 Cluster: Chromosome undetermined scaffold_215, w...    91   8e-17
UniRef50_Q5DI00 Cluster: SJCHGC01183 protein; n=2; Schistosoma j...    91   1e-16
UniRef50_Q5C361 Cluster: SJCHGC05676 protein; n=1; Schistosoma j...    90   1e-16
UniRef50_Q5ZP28 Cluster: PTPS protein; n=7; Bracovirus|Rep: PTPS...    90   2e-16
UniRef50_UPI000150A051 Cluster: Protein-tyrosine phosphatase con...    89   2e-16
UniRef50_Q20108 Cluster: Putative uncharacterized protein; n=3; ...    89   2e-16
UniRef50_O44180 Cluster: Putative uncharacterized protein M04G7....    89   2e-16
UniRef50_Q6BJ79 Cluster: Debaryomyces hansenii chromosome G of s...    89   2e-16
UniRef50_Q75CG0 Cluster: ACL041Cp; n=1; Eremothecium gossypii|Re...    89   3e-16
UniRef50_P32586 Cluster: Tyrosine-protein phosphatase 2; n=1; Sc...    89   3e-16
UniRef50_Q7PYY8 Cluster: ENSANGP00000019140; n=1; Anopheles gamb...    88   7e-16
UniRef50_A6S859 Cluster: Putative uncharacterized protein; n=2; ...    88   7e-16
UniRef50_A5E4K6 Cluster: Putative uncharacterized protein; n=1; ...    88   7e-16
UniRef50_Q7PMF4 Cluster: ENSANGP00000006015; n=2; Culicidae|Rep:...    87   1e-15
UniRef50_Q5I128 Cluster: PTP 2; n=1; Microplitis demolitor braco...    87   1e-15
UniRef50_O01736 Cluster: Putative uncharacterized protein F20H11...    87   1e-15
UniRef50_Q9W0R3 Cluster: CG1228-PA, isoform A; n=5; Diptera|Rep:...    87   2e-15
UniRef50_Q8WSF2 Cluster: Split central complex; n=3; Sophophora|...    87   2e-15
UniRef50_Q4E4C8 Cluster: Tyrosine specific protein phosphatase, ...    87   2e-15
UniRef50_A7RS60 Cluster: Predicted protein; n=2; Nematostella ve...    87   2e-15
UniRef50_Q86QP9 Cluster: Nontransmembrane protein tyrosine phosp...    86   2e-15
UniRef50_A6RGK2 Cluster: Predicted protein; n=1; Ajellomyces cap...    86   2e-15
UniRef50_UPI0000D5706F Cluster: PREDICTED: similar to protein ty...    86   3e-15
UniRef50_Q4RMH6 Cluster: Chromosome 10 SCAF15019, whole genome s...    85   4e-15
UniRef50_Q09962 Cluster: Related to islet cell diabetes autoanti...    85   4e-15
UniRef50_A2PZY5 Cluster: GfV-C18-ORF1; n=3; Glypta fumiferanae i...    84   1e-14
UniRef50_Q6BZT9 Cluster: Similar to DEHA0A11495g Debaryomyces ha...    84   1e-14
UniRef50_UPI000065FA99 Cluster: Receptor-type tyrosine-protein p...    83   2e-14
UniRef50_Q4RXD7 Cluster: Chromosome 11 SCAF14979, whole genome s...    82   4e-14
UniRef50_Q5I147 Cluster: PTP 1; n=2; Microplitis demolitor braco...    82   4e-14
UniRef50_Q9UDA8 Cluster: Protein-tyrosine phosphatase; n=24; Eut...    82   4e-14
UniRef50_Q86QP7 Cluster: Protein tyrosine phosphatase receptor-l...    82   5e-14
UniRef50_Q4FEY5 Cluster: Protein tyrosine phosphatase; n=2; Brac...    81   6e-14
UniRef50_Q5ZP77 Cluster: PTP D protein; n=2; Cotesia congregata ...    81   8e-14
UniRef50_P28202 Cluster: Tyrosine-protein phosphatase 10; n=30; ...    81   8e-14
UniRef50_UPI0000D5641B Cluster: PREDICTED: similar to Tyrosine-p...    81   1e-13
UniRef50_Q4SXQ1 Cluster: Chromosome 6 SCAF12355, whole genome sh...    81   1e-13
UniRef50_Q769I0 Cluster: Endostyle specific protein 11; n=1; Cio...    81   1e-13
UniRef50_UPI0000D9A0A3 Cluster: PREDICTED: similar to Tyrosine-p...    80   1e-13
UniRef50_Q5ZP10 Cluster: PTPW protein; n=2; Cotesia congregata b...    80   1e-13
UniRef50_A2PZT1 Cluster: GfV-B33-ORF1; n=2; Glypta fumiferanae i...    80   1e-13
UniRef50_Q537E7 Cluster: Protein tyrosine phosphatase; n=2; Brac...    80   2e-13
UniRef50_Q5I137 Cluster: PTP 2; n=2; Microplitis demolitor braco...    79   3e-13
UniRef50_Q3LDS6 Cluster: Protein-tyrosine phosphatase 1; n=1; Ny...    79   3e-13
UniRef50_Q4SE53 Cluster: Chromosome undetermined SCAF14625, whol...    79   3e-13
UniRef50_Q4W5R1 Cluster: Putative uncharacterized protein; n=1; ...    79   3e-13
UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad...    78   6e-13
UniRef50_A5DMM8 Cluster: Putative uncharacterized protein; n=1; ...    78   6e-13
UniRef50_UPI0000EBF021 Cluster: PREDICTED: similar to protein-ty...    77   1e-12
UniRef50_P28212 Cluster: Tyrosine-protein phosphatase 20; n=8; S...    77   1e-12
UniRef50_Q61HU2 Cluster: Putative uncharacterized protein CBG105...    77   2e-12
UniRef50_Q5ACN2 Cluster: Putative uncharacterized protein PTP3; ...    76   3e-12
UniRef50_UPI00005A12F1 Cluster: PREDICTED: similar to Receptor-t...    75   4e-12
UniRef50_Q9N4H5 Cluster: Putative uncharacterized protein; n=4; ...    75   4e-12
UniRef50_A7T089 Cluster: Predicted protein; n=1; Nematostella ve...    75   4e-12
UniRef50_UPI0000E47710 Cluster: PREDICTED: similar to ENSANGP000...    75   5e-12
UniRef50_Q16344 Cluster: Protein-tyrosine phosphatase; n=8; Eute...    75   5e-12
UniRef50_Q6FLK0 Cluster: Candida glabrata strain CBS138 chromoso...    75   5e-12
UniRef50_Q4S655 Cluster: Chromosome 9 SCAF14729, whole genome sh...    75   7e-12
UniRef50_A2PZQ7 Cluster: GfV-B7-ORF1; n=1; Glypta fumiferanae ic...    75   7e-12
UniRef50_Q4EW65 Cluster: Protein tyrosine phosphatase B; n=2; En...    74   9e-12
UniRef50_Q95XJ2 Cluster: Putative uncharacterized protein; n=1; ...    74   1e-11
UniRef50_Q5W3L1 Cluster: Putative tyrosine phosphatase protein; ...    73   2e-11
UniRef50_Q60NT8 Cluster: Putative uncharacterized protein CBG225...    73   2e-11
UniRef50_Q60NY2 Cluster: Putative uncharacterized protein CBG225...    73   2e-11
UniRef50_A1C8Z4 Cluster: Protein tyrosine phosphatase (Pyp1), pu...    73   2e-11
UniRef50_UPI0001555693 Cluster: PREDICTED: similar to protein ty...    73   3e-11
UniRef50_UPI0000D55FE8 Cluster: PREDICTED: similar to CG9311-PA;...    71   7e-11
UniRef50_Q2THU7 Cluster: PTP9; n=1; Glyptapanteles indiensis bra...    71   9e-11
UniRef50_P28209 Cluster: Tyrosine-protein phosphatase 17; n=1; S...    71   9e-11
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul...    70   2e-10
UniRef50_Q49AC9 Cluster: PTPRM protein; n=23; Euteleostomi|Rep: ...    70   2e-10
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA...    69   3e-10
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le...    69   3e-10
UniRef50_Q9XWA6 Cluster: Putative uncharacterized protein; n=2; ...    69   3e-10
UniRef50_Q9V3V3 Cluster: CG9493-PA; n=3; Drosophila|Rep: CG9493-...    69   3e-10
UniRef50_Q86QP6 Cluster: Protein tyrosine phosphatase receptor-l...    69   3e-10
UniRef50_Q06DZ5 Cluster: EAK-6B isoform; n=3; Caenorhabditis ele...    69   3e-10
UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve...    69   3e-10
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n...    69   4e-10
UniRef50_P28208 Cluster: Tyrosine-protein phosphatase 16; n=1; S...    69   4e-10
UniRef50_UPI0000DD8783 Cluster: PREDICTED: similar to Tyrosine-p...    68   6e-10
UniRef50_A7TKR6 Cluster: Putative uncharacterized protein; n=1; ...    68   6e-10
UniRef50_P28204 Cluster: Tyrosine-protein phosphatase 12; n=1; S...    68   6e-10
UniRef50_UPI0000DB7602 Cluster: PREDICTED: similar to CG9311-PA;...    67   1e-09
UniRef50_A6S541 Cluster: Putative uncharacterized protein; n=2; ...    67   1e-09
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo...    67   1e-09
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh...    67   1e-09
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia...    67   1e-09
UniRef50_Q0V1L0 Cluster: Putative uncharacterized protein; n=1; ...    67   1e-09
UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ...    67   1e-09
UniRef50_P28198 Cluster: Tyrosine-protein phosphatase 6; n=1; St...    67   1e-09
UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase...    66   2e-09
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty...    66   2e-09
UniRef50_Q5C820 Cluster: SJCHGC07650 protein; n=1; Schistosoma j...    66   2e-09
UniRef50_Q4THX3 Cluster: Chromosome undetermined SCAF2602, whole...    66   3e-09
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol...    66   3e-09
UniRef50_Q2R9R4 Cluster: Protein-tyrosine phosphatase containing...    66   3e-09
UniRef50_A7ERJ0 Cluster: Putative uncharacterized protein; n=1; ...    66   3e-09
UniRef50_Q5ZP76 Cluster: PTPI protein; n=5; Bracovirus|Rep: PTPI...    65   4e-09
UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot...    65   4e-09
UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho...    65   6e-09
UniRef50_A0T025 Cluster: Protein tyrosine phosphatase; n=4; Brac...    65   6e-09
UniRef50_Q8MYN1 Cluster: Putative uncharacterized protein; n=4; ...    65   6e-09
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae...    65   6e-09
UniRef50_A4RKV6 Cluster: Putative uncharacterized protein; n=1; ...    65   6e-09
UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...    65   6e-09
UniRef50_Q5ZP29 Cluster: PTPE protein; n=6; Bracovirus|Rep: PTPE...    64   8e-09
UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin...    64   8e-09
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil...    64   8e-09
UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-...    64   8e-09
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ...    64   1e-08
UniRef50_O17889 Cluster: Putative uncharacterized protein; n=1; ...    64   1e-08
UniRef50_Q9P664 Cluster: Related to protein-tyrosine-phosphatase...    64   1e-08
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph...    64   1e-08
UniRef50_P28218 Cluster: Tyrosine-protein phosphatase 26; n=2; S...    64   1e-08
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut...    64   1e-08
UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2...    63   2e-08
UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos...    63   2e-08
UniRef50_Q2THV3 Cluster: PTP5; n=1; Glyptapanteles indiensis bra...    63   2e-08
UniRef50_A0T028 Cluster: Protein tyrosine phosphatase; n=5; Brac...    63   2e-08
UniRef50_Q2GUP8 Cluster: Putative uncharacterized protein; n=1; ...    63   2e-08
UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein;...    63   2e-08
UniRef50_Q4RDK9 Cluster: Chromosome 13 SCAF16223, whole genome s...    63   2e-08
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia...    63   2e-08
UniRef50_A7T0L8 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ...    62   3e-08
UniRef50_Q6CRT4 Cluster: Kluyveromyces lactis strain NRRL Y-1140...    62   3e-08
UniRef50_Q4RI64 Cluster: Chromosome 8 SCAF15044, whole genome sh...    62   4e-08
UniRef50_Q5I139 Cluster: PTP 3; n=1; Microplitis demolitor braco...    62   4e-08
UniRef50_Q64504 Cluster: Protein-tyrosine-phosphatase; n=2; Mamm...    62   4e-08
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot...    62   4e-08
UniRef50_Q616S5 Cluster: Putative uncharacterized protein CBG151...    62   4e-08
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H...    62   4e-08
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd...    62   4e-08
UniRef50_UPI000050473A Cluster: UPI000050473A related cluster; n...    62   5e-08
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E...    62   5e-08
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ...    62   5e-08
UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc...    61   7e-08
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s...    61   7e-08
UniRef50_Q4S635 Cluster: Chromosome 9 SCAF14729, whole genome sh...    61   7e-08
UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb...    61   7e-08
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099...    61   7e-08
UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase...    61   9e-08
UniRef50_A0SZZ1 Cluster: Protein tyrosine phosphatase; n=1; Cote...    61   9e-08
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:...    61   9e-08
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ...    61   9e-08
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr...    61   9e-08
UniRef50_Q1LXS1 Cluster: Protein tyrosine phosphatase, non-recep...    60   1e-07
UniRef50_O01777 Cluster: Putative uncharacterized protein W03F11...    60   1e-07
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R...    60   1e-07
UniRef50_Q5W3L0 Cluster: Putative tyrosine phosphatase protein; ...    60   2e-07
UniRef50_Q16Q35 Cluster: Putative uncharacterized protein; n=1; ...    60   2e-07
UniRef50_A6RDG7 Cluster: Predicted protein; n=1; Ajellomyces cap...    60   2e-07
UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A...    60   2e-07
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut...    60   2e-07
UniRef50_Q4TIE2 Cluster: Chromosome undetermined SCAF2213, whole...    60   2e-07
UniRef50_A2PZQ2 Cluster: GfV-A10-ORF1; n=1; Glypta fumiferanae i...    60   2e-07
UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s...    59   3e-07
UniRef50_A2PZS9 Cluster: GfV-B28-ORF1; n=1; Glypta fumiferanae i...    59   3e-07
UniRef50_A2VEF6 Cluster: IP14232p; n=8; Diptera|Rep: IP14232p - ...    59   3e-07
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ...    59   3e-07
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ...    59   3e-07
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;...    59   3e-07
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr...    59   3e-07
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;...    59   4e-07
UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ...    59   4e-07
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet...    59   4e-07
UniRef50_A7SZ84 Cluster: Predicted protein; n=4; Nematostella ve...    58   5e-07
UniRef50_UPI0000F21F11 Cluster: PREDICTED: hypothetical protein,...    58   7e-07
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh...    58   7e-07
UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei...    58   9e-07
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco...    58   9e-07
UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol...    58   9e-07
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1...    58   9e-07
UniRef50_A2PZU2 Cluster: GfV-B46-ORF1; n=1; Glypta fumiferanae i...    58   9e-07
UniRef50_Q4P610 Cluster: Putative uncharacterized protein; n=1; ...    58   9e-07
UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygot...    58   9e-07
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty...    57   1e-06
UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;...    57   1e-06
UniRef50_UPI00005A46F1 Cluster: PREDICTED: similar to protein ty...    57   1e-06
UniRef50_A2PZV7 Cluster: GfV-B61-ORF1; n=1; Glypta fumiferanae i...    57   1e-06
UniRef50_Q17MG6 Cluster: Protein-tryrosine phosphatase; n=1; Aed...    57   1e-06
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos...    57   1e-06
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop...    57   1e-06
UniRef50_P28195 Cluster: Tyrosine-protein phosphatase 3; n=1; St...    57   1e-06
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut...    57   1e-06
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi...    57   2e-06
UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome s...    57   2e-06
UniRef50_Q18415 Cluster: Putative uncharacterized protein; n=1; ...    57   2e-06
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92...    56   2e-06
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole...    56   2e-06
UniRef50_Q7Z7G1 Cluster: MIST; n=18; Eutheria|Rep: MIST - Homo s...    56   2e-06
UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain...    56   3e-06
UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3; ...    56   3e-06
UniRef50_Q4Q1K3 Cluster: Protein-tyrosine phosphatase 1-like pro...    56   3e-06
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd...    56   3e-06
UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro...    56   4e-06
UniRef50_UPI0000D577F5 Cluster: PREDICTED: similar to CG10975-PA...    56   4e-06
UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1...    56   4e-06
UniRef50_A2PZV8 Cluster: GfV-B62-ORF1; n=1; Glypta fumiferanae i...    56   4e-06
UniRef50_P28197 Cluster: Tyrosine-protein phosphatase 5; n=1; St...    56   4e-06
UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote...    55   5e-06
UniRef50_Q64500 Cluster: Protein-tyrosine-phosphatase; n=5; Eute...    55   6e-06
UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb...    55   6e-06
UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ...    55   6e-06
UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;...    55   6e-06
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve...    55   6e-06
UniRef50_Q5W3L2 Cluster: Putative tyrosine phosphatase protein; ...    54   8e-06
UniRef50_Q3UWY6 Cluster: In vitro fertilized eggs cDNA, RIKEN fu...    54   8e-06
UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG164...    54   8e-06
UniRef50_A7SQ18 Cluster: Predicted protein; n=1; Nematostella ve...    54   8e-06
UniRef50_Q5K7Z6 Cluster: Putative uncharacterized protein; n=1; ...    54   8e-06
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ...    54   8e-06
UniRef50_Q5W3K8 Cluster: Putative tyrosine phosphatase protein; ...    54   1e-05
UniRef50_Q61FA2 Cluster: Putative uncharacterized protein CBG117...    54   1e-05
UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve...    54   1e-05
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am...    54   1e-05
UniRef50_P40048 Cluster: Tyrosine-protein phosphatase 3; n=2; Sa...    54   1e-05
UniRef50_UPI000058412C Cluster: PREDICTED: hypothetical protein;...    54   1e-05
UniRef50_Q9BL78 Cluster: Putative uncharacterized protein; n=1; ...    54   1e-05
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B...    54   1e-05
UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s...    53   2e-05
UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat...    53   2e-05
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote...    53   2e-05
UniRef50_Q2THV2 Cluster: PTP4; n=10; Bracovirus|Rep: PTP4 - Glyp...    53   3e-05
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia...    53   3e-05
UniRef50_Q20179 Cluster: Putative uncharacterized protein; n=2; ...    53   3e-05
UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|...    53   3e-05
UniRef50_A4RDP8 Cluster: Putative uncharacterized protein; n=1; ...    53   3e-05
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E...    53   3e-05
UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E...    53   3e-05
UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;...    53   3e-05
UniRef50_P28199 Cluster: Tyrosine-protein phosphatase 7; n=17; F...    53   3e-05
UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P4...    53   3e-05
UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad...    52   3e-05
UniRef50_Q13322-2 Cluster: Isoform 1 of Q13322 ; n=5; Homo/Pan/G...    52   3e-05
UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh...    52   3e-05
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol...    52   3e-05

>UniRef50_Q16YG8 Cluster: Protein tyrosine phosphatase n11; n=2;
           Aedes aegypti|Rep: Protein tyrosine phosphatase n11 -
           Aedes aegypti (Yellowfever mosquito)
          Length = 511

 Score =  416 bits (1024), Expect = e-114
 Identities = 230/467 (49%), Positives = 296/467 (63%), Gaps = 27/467 (5%)

Query: 123 IIRRKDNKYDVGGGQQFDDLVSLIEYYRSFPMVETTGEVLRLIQPFNATRIQVRHFHTRV 182
           +IR  +NKYDVGGGQ+F+ L  LIE+Y+  PMVET G V+ L QPFNATRI       RV
Sbjct: 1   MIRWHENKYDVGGGQKFNTLCDLIEHYKRNPMVETCGTVVHLRQPFNATRITAAGIDARV 60

Query: 183 KQLQKENEGPIESMAY-KQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFD 241
           +QLQ+EN     S  Y K GFWEEFE+LQ  E    F R EG + EN  KNRYKNI+PFD
Sbjct: 61  EQLQRENG----SHCYGKGGFWEEFESLQQQECRYTFSRREGQRNENRVKNRYKNILPFD 116

Query: 242 HTRVILKDIPPDGPPGSDYINANYIRCDSMDSISDSQEFTGNGSTENGKDGTPSKAKDKS 301
           HTRV LKD+    P G++YINANYIR  +    +D    + N + + G     S   +  
Sbjct: 117 HTRVKLKDVDSTHP-GAEYINANYIRQPTESEQNDMNSSSENLAQQQGHQNNNSTTNNAI 175

Query: 302 SPVHTSVIVTEEPVK---SSKKVHGNGTHKLPAFEPSVLRPNPNYFNTTIP---KSATET 355
               T   + ++P K   S + ++   +        S  + N +  +T +    +S +++
Sbjct: 176 ----TYASINQQPAKNCQSCQLLNKPCSQCSMKANESKHKRNDSLTSTRLQLQSQSQSKS 231

Query: 356 ENGVPTVHVYN-----KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCE 410
             G  +  + +     KTYIATQGCL+ TI  FW+MIWQED R+I+MTTKEIERGK KCE
Sbjct: 232 SIGSGSSLLRDEKDLFKTYIATQGCLANTIQDFWNMIWQEDTRVIVMTTKEIERGKKKCE 291

Query: 411 RYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRV 470
           +YWPD  +++      +    E+ST DYTLR FL++ + +   +R I+ +HF  WPDH V
Sbjct: 292 KYWPDPQQSKEWGSAKVTCLSETSTADYTLREFLLSWRGQD--ERKIFQYHFQVWPDHGV 349

Query: 471 PSEPGRVLNILLDVNYRLQQI-MTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRK 529
           PS+PG VLN L DVN R +Q+ + G  P     +CVHCSAGIGRTGTFIVIDMILDQI +
Sbjct: 350 PSDPGCVLNFLQDVNARQEQLQLEGLTP---GPICVHCSAGIGRTGTFIVIDMILDQIDR 406

Query: 530 EGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQR 576
           EG DCEIDI RT+QMVR QRSGMVQ EAQYKF+Y AV  +I+T  QR
Sbjct: 407 EGLDCEIDIQRTIQMVRSQRSGMVQTEAQYKFVYFAVQHYIQTLFQR 453


>UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;
           n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase
           corkscrew - Drosophila melanogaster (Fruit fly)
          Length = 845

 Score =  260 bits (637), Expect = 8e-68
 Identities = 158/332 (47%), Positives = 200/332 (60%), Gaps = 56/332 (16%)

Query: 1   MITRRWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVRRGNEVTHIKIQNNG 60
           M +RRWFHP+++G++AEKLL E G DG FLAR SSSN G FTLSVRRGNEVTHIKIQNNG
Sbjct: 1   MSSRRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNG 60

Query: 61  EFLDLYGD------PTTERWY--HGQLTAKEAERMMME------------------NGKN 94
           +F DLYG       P   ++Y  +G+L  K  + + ++                  +GK 
Sbjct: 61  DFFDLYGGEKFATLPELVQYYMENGELKEKNGQAIELKQPLICAEPTTERWFHGNLSGKE 120

Query: 95  GSFLVRE-----------SQSQPGDFVLSVRTRDRVTHVIIRRKDNKYDVGGGQQFDDLV 143
              L+ E           SQS+PGDFVLSVRT D+VTHV+IR +D KYDVGGG+ F  L 
Sbjct: 121 AEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKYDVGGGESFGTLS 180

Query: 144 SLIEYYRSFPMVETTGEVLRLIQPFNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFW 203
            LI++Y+  PMVET G V+ L QPFNATRI     + RV+QL             K GFW
Sbjct: 181 ELIDHYKRNPMVETCGTVVHLRQPFNATRITAAGINARVEQL------------VKGGFW 228

Query: 204 EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
           EEFE+LQ  ++   F R EG K EN  KNRY+NI+P+DHTRV L D+      G++YINA
Sbjct: 229 EEFESLQ-QDSRDTFSRNEGYKQENRLKNRYRNILPYDHTRVKLLDV-EHSVAGAEYINA 286

Query: 264 NYIRCDSMDSISDSQEFTGNGSTENGKDGTPS 295
           NYIR       +D   +  + S+E+     PS
Sbjct: 287 NYIRLP-----TDGDLYNMSSSSESLNSSVPS 313



 Score =  260 bits (637), Expect = 8e-68
 Identities = 125/210 (59%), Positives = 150/210 (71%), Gaps = 8/210 (3%)

Query: 367 KTYIATQGCLST----TIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
           KTYIATQGCL T    T+  FW+M+WQE+ R+I+MTTKE ERGK KC RYWPD  ++E  
Sbjct: 443 KTYIATQGCLLTQQVNTVTDFWNMVWQENTRVIVMTTKEYERGKEKCARYWPDEGRSEQF 502

Query: 423 KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
               I    E+ST DYTLR FLV+ +D+    R I+H+HF  WPDH VP++PG VLN L 
Sbjct: 503 GHARIQCVSENSTSDYTLREFLVSWRDQPA--RRIFHYHFQVWPDHGVPADPGCVLNFLQ 560

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
           DVN R   +    + P    +CVHCSAGIGRTGTFIVIDMILDQI + G D EIDI RT+
Sbjct: 561 DVNTRQSHLAQAGEKPGP--ICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTI 618

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
           QMVR QRSG+VQ EAQYKF+Y AV  +I+T
Sbjct: 619 QMVRSQRSGLVQTEAQYKFVYYAVQHYIQT 648


>UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor
           type 11; n=73; Bilateria|Rep: Tyrosine-protein
           phosphatase non-receptor type 11 - Homo sapiens (Human)
          Length = 597

 Score =  253 bits (620), Expect = 9e-66
 Identities = 153/314 (48%), Positives = 188/314 (59%), Gaps = 52/314 (16%)

Query: 1   MITRRWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVRRGNEVTHIKIQNNG 60
           M +RRWFHP++ GV+AE LL+  G DG FLARPS SN GDFTLSVRR   VTHIKIQN G
Sbjct: 1   MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG 60

Query: 61  EFLDLYGD------PTTERWY---HGQLTAKEAERMMME------------------NGK 93
           ++ DLYG           ++Y   HGQL  K  + + ++                  +GK
Sbjct: 61  DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK 120

Query: 94  NGSFLVRES---------QSQ--PGDFVLSVRTRD----------RVTHVIIRRKDNKYD 132
               L+ E          +SQ  PGDFVLSVRT D          +VTHV+IR ++ KYD
Sbjct: 121 EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD 180

Query: 133 VGGGQQFDDLVSLIEYYRSFPMVETTGEVLRLIQPFNATRIQVRHFHTRVKQLQKENEGP 192
           VGGG++FD L  L+E+Y+  PMVET G VL+L QP N TRI      +RV++L K  E  
Sbjct: 181 VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAE-- 238

Query: 193 IESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPP 252
             +   KQGFWEEFETLQ  E   L+ R EG + EN  KNRYKNI+PFDHTRV+L D  P
Sbjct: 239 -TTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDP 297

Query: 253 DGPPGSDYINANYI 266
           +  P SDYINAN I
Sbjct: 298 N-EPVSDYINANII 310



 Score =  243 bits (594), Expect = 1e-62
 Identities = 120/245 (48%), Positives = 164/245 (66%), Gaps = 17/245 (6%)

Query: 339 PNPNYFNTTI--PKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIII 396
           P  +Y N  I  P+  T+  N  P      K+YIATQGCL  T+  FW M++QE+ R+I+
Sbjct: 300 PVSDYINANIIMPEFETKCNNSKP-----KKSYIATQGCLQNTVNDFWRMVFQENSRVIV 354

Query: 397 MTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVK-- 454
           MTTKE+ERGK KC +YWPD    +      + N  ES+  DYTLR   ++K  +  ++  
Sbjct: 355 MTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGN 414

Query: 455 --RTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIG 512
             RT++ +HF  WPDH VPS+PG VL+ L +V+++ + IM          V VHCSAGIG
Sbjct: 415 TERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDA------GPVVVHCSAGIG 468

Query: 513 RTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
           RTGTFIVID+++D IR++G DC+ID+ +T+QMVR QRSGMVQ EAQY+FIYMAV  +IET
Sbjct: 469 RTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIET 528

Query: 573 EKQRV 577
            ++R+
Sbjct: 529 LQRRI 533


>UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase,
           non-receptor type 11 (Noonan syndrome 1); n=1; Danio
           rerio|Rep: protein tyrosine phosphatase, non-receptor
           type 11 (Noonan syndrome 1) - Danio rerio
          Length = 564

 Score =  243 bits (595), Expect = 9e-63
 Identities = 111/211 (52%), Positives = 153/211 (72%), Gaps = 6/211 (2%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           ++YIATQGCL  TI  FW M++QE+ R+I+MTTKE+ERGK KC +YWPD++  +      
Sbjct: 296 RSYIATQGCLQNTISDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDVSALKEYGAMR 355

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           + N  E+   DY LR   ++K  +   +RT++ +HF AWPDH VP +PG VL+ L +V  
Sbjct: 356 VRNVKETMAHDYILRELKLSKVGQGNTERTVWQYHFRAWPDHGVPGDPGGVLDFLEEVKL 415

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
           + Q+ +TG  P     + VHCSAGIGRTGTFIVID+++D IR++G DC+ID+ +T+QMVR
Sbjct: 416 K-QEGITGAGP-----IVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVR 469

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
            QRSGMVQ EAQY+FIYMAV  +IET ++R+
Sbjct: 470 SQRSGMVQTEAQYRFIYMAVQHYIETLQRRI 500



 Score =  234 bits (573), Expect = 4e-60
 Identities = 134/293 (45%), Positives = 166/293 (56%), Gaps = 23/293 (7%)

Query: 5   RWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVRRGNEVTHIKIQNNGEFLD 64
           RWFHP++ GV+AE LL+  G DG FLARPS SN GDFTLSVRR   VTHIKIQN G++ D
Sbjct: 5   RWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYD 64

Query: 65  L--------YGDPTTERWYHGQLTAKEAERMMMENGK------NGSFLVRESQSQPGDFV 110
           L        Y       W            +  EN        +  +L      Q  +  
Sbjct: 65  LWLFAKTRLYKQHYDPLWQTNANMGPSVRLLKAENEPITAHIFDNMYLKTVLLLQKNNLY 124

Query: 111 L-----SVRTRDRVTHVIIRRKDNKYDVGGGQQFDDLVSLIEYYRSFPMVETTGEVLRLI 165
           L     ++    RV  +II + D KYDVGGG++FD L  L+E+Y+  PMVET G VL+L 
Sbjct: 125 LVPNEQNISNITRVVFIIINKHDLKYDVGGGEKFDSLTDLVEHYKKNPMVETLGTVLQLK 184

Query: 166 QPFNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSK 225
           QP N TRI      +RV++L K  E   +    KQGFWEEFETLQ  E   L+ R EG +
Sbjct: 185 QPLNTTRINAAEIESRVRELSKLAEATDK---VKQGFWEEFETLQQQECKLLYSRKEGQR 241

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCDSMDSISDSQ 278
           PEN  KNRYKNI+PFDHTRV+L D       GSDYINAN I  D+    ++S+
Sbjct: 242 PENKNKNRYKNILPFDHTRVVLTD-GDVNEQGSDYINANLIMPDNEAKSNNSK 293


>UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor
           type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase
           non-receptor type 6 - Homo sapiens (Human)
          Length = 595

 Score =  238 bits (582), Expect = 3e-61
 Identities = 107/211 (50%), Positives = 145/211 (68%), Gaps = 6/211 (2%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           KTYIA+QGCL  T+  FW M WQE+ R+I+MTT+E+E+G+ KC  YWP++        Y+
Sbjct: 319 KTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYS 378

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           + N  E  T +Y LR   V+  D   + R I+H+ + +WPDH VPSEPG VL+ L  +N 
Sbjct: 379 VTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQ 438

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
           R + +      P    + VHCSAGIGRTGT IVIDM+++ I  +G DC+IDI +T+QMVR
Sbjct: 439 RQESL------PHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVR 492

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
            QRSGMVQ EAQYKFIY+A+ +FIET K+++
Sbjct: 493 AQRSGMVQTEAQYKFIYVAIAQFIETTKKKL 523



 Score =  192 bits (467), Expect = 3e-47
 Identities = 100/209 (47%), Positives = 132/209 (63%), Gaps = 13/209 (6%)

Query: 68  DPTTERWYHGQLTAKEAERMMMENGKNGSFLVRESQSQPGDFVLSVRTRD---------R 118
           DPT+ERWYHG ++  +AE ++   G+  +FLVRES SQPGDFVLSV +           R
Sbjct: 104 DPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLR 163

Query: 119 VTHVIIRRKDNKYDVGGGQQFDDLVSLIEYYRSFPMVETTGEVLRLIQPFNATRIQVRHF 178
           VTH+ +  +  +Y VGG + FD L  L+E+++   + E +G  + L QP+ ATR+     
Sbjct: 164 VTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADI 223

Query: 179 HTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNII 238
             RV +L K+ E   E  A K GFWEEFE+LQ  E   L  R+EG +PEN  KNRYKNI+
Sbjct: 224 ENRVLELNKKQES--EDTA-KAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNIL 280

Query: 239 PFDHTRVILKDIPPDGPPGSDYINANYIR 267
           PFDH+RVIL+       PGSDYINANYI+
Sbjct: 281 PFDHSRVILQG-RDSNIPGSDYINANYIK 308



 Score = 90.6 bits (215), Expect = 1e-16
 Identities = 41/63 (65%), Positives = 50/63 (79%)

Query: 5  RWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVRRGNEVTHIKIQNNGEFLD 64
          RWFH  L+G+DAE LL   G  G FLARPS  N+GDF+LSVR G++VTHI+IQN+G+F D
Sbjct: 3  RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62

Query: 65 LYG 67
          LYG
Sbjct: 63 LYG 65



 Score = 82.6 bits (195), Expect = 3e-14
 Identities = 39/101 (38%), Positives = 60/101 (59%), Gaps = 2/101 (1%)

Query: 73  RWYHGQLTAKEAERMMMENGKNGSFLVRESQSQPGDFVLSVRTRDRVTHVIIRRKDNKYD 132
           RW+H  L+  +AE ++   G +GSFL R S+   GDF LSVR  D+VTH+ I+   + YD
Sbjct: 3   RWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62

Query: 133 VGGGQQFDDLVSLIEYY--RSFPMVETTGEVLRLIQPFNAT 171
           + GG++F  L  L+EYY  +   + +  G ++ L  P N +
Sbjct: 63  LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCS 103



 Score = 41.9 bits (94), Expect = 0.047
 Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 9/67 (13%)

Query: 3   TRRWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVRRGN---------EVTH 53
           + RW+H  ++G  AE LL   G    FL R S S  GDF LSV              VTH
Sbjct: 107 SERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTH 166

Query: 54  IKIQNNG 60
           IK+   G
Sbjct: 167 IKVMCEG 173


>UniRef50_Q9NL10 Cluster: AmPTPN6 protein; n=3; Coelomata|Rep:
           AmPTPN6 protein - Branchiostoma belcheri (Amphioxus)
          Length = 275

 Score =  219 bits (534), Expect = 2e-55
 Identities = 107/196 (54%), Positives = 133/196 (67%), Gaps = 6/196 (3%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKK 448
           QE+ R+I+MTTKE+ERGK KC RYWP+    +      I +  E++ PDYTLR   VTK+
Sbjct: 1   QENTRVIVMTTKEVERGKNKCTRYWPEPGTKKSYGILLIRHLSETNFPDYTLRELEVTKE 60

Query: 449 DETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCS 508
            E    RTIYH+HF AWPDH VP +PG VLN L + N + + I      P    + VHCS
Sbjct: 61  GENNPPRTIYHYHFKAWPDHGVPGDPGCVLNFLHETNTKQENI------PDVGPMVVHCS 114

Query: 509 AGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
           AGIGRTGTFIVID+IL+ I+K G DCEIDI +T+Q +R QRSGMVQ EAQYKF+YMAV  
Sbjct: 115 AGIGRTGTFIVIDIILNLIKKFGLDCEIDIQKTIQHMRTQRSGMVQTEAQYKFVYMAVQH 174

Query: 569 FIETEKQRVGLGPEAA 584
            IET  +R+    + A
Sbjct: 175 HIETVSKRIAAQTKVA 190


>UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to
           protein-tyrosine phosphatase; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to protein-tyrosine
           phosphatase - Strongylocentrotus purpuratus
          Length = 533

 Score =  215 bits (525), Expect = 3e-54
 Identities = 103/190 (54%), Positives = 134/190 (70%), Gaps = 7/190 (3%)

Query: 57  QNNGEFLDLY-----GDPTTERWYHGQLTAKEAERMMMENGKNGSFLVRESQSQPGDFVL 111
           + NG+ ++L       DPT ERW+HG +T KEAE+ +++ GKNGS+LVRES S+PGD+VL
Sbjct: 90  ERNGQMIELKYPLNCADPTNERWFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVL 149

Query: 112 SVRTRDRVTHVIIRRKDNKYDVGGGQQFDDLVSLIEYYRSFPMVETTGEVLRLIQPFNAT 171
           SVRT D+VTHV+IR +D KYDVGGG+QF+ L  L+++YR  PMVETTG V+ L  PFNAT
Sbjct: 150 SVRTEDKVTHVMIRCQDTKYDVGGGEQFETLTDLVDHYRKNPMVETTGYVVHLKVPFNAT 209

Query: 172 RIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRK 231
           RI       RV+ L+KE +    S   K GF EEFE LQ+++N  L  R  G K EN  K
Sbjct: 210 RISASGIRNRVEVLEKETKSRENSK--KAGFEEEFEALQLLDNKHLLPRKIGDKAENKSK 267

Query: 232 NRYKNIIPFD 241
           NRYKNI+P++
Sbjct: 268 NRYKNILPYN 277



 Score =  192 bits (469), Expect = 2e-47
 Identities = 93/170 (54%), Positives = 118/170 (69%), Gaps = 6/170 (3%)

Query: 408 KCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPD 467
           KC RYWPD N  +     T+ +  E S  DY LR F ++ KD     R ++HFHF +WPD
Sbjct: 292 KCCRYWPDANTKKDTGVITVTHISEQSMADYDLREFSMSHKDFPEESRPMFHFHFKSWPD 351

Query: 468 HRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQI 527
           H VPS+P RVLN L DVN + +     T P A +++ VHCSAGIGRTGTFIVID+IL+ I
Sbjct: 352 HGVPSDPSRVLNFLQDVNKKQE-----TFPDAGSII-VHCSAGIGRTGTFIVIDIILNLI 405

Query: 528 RKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
           ++ G DCEIDI+ T+++VR QRSG+VQ EAQYKF+Y AV  +IET  QRV
Sbjct: 406 KQHGLDCEIDIYNTIRLVRQQRSGLVQTEAQYKFVYRAVQHYIETLSQRV 455



 Score =  106 bits (255), Expect = 1e-21
 Identities = 46/67 (68%), Positives = 55/67 (82%)

Query: 1  MITRRWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVRRGNEVTHIKIQNNG 60
          M +RRWFHP+++G++AE+LL+  G DG FL RPS SN GDFTLSVRR  EVTHIKIQN G
Sbjct: 1  MASRRWFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTG 60

Query: 61 EFLDLYG 67
          +F DLYG
Sbjct: 61 DFFDLYG 67



 Score = 87.4 bits (207), Expect = 1e-15
 Identities = 43/121 (35%), Positives = 69/121 (57%), Gaps = 3/121 (2%)

Query: 71  TERWYHGQLTAKEAERMMMENGKNGSFLVRESQSQPGDFVLSVRTRDRVTHVIIRRKDNK 130
           + RW+H  ++  EAE++++ NG +G FL R S+S PGDF LSVR    VTH+ I+   + 
Sbjct: 3   SRRWFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTGDF 62

Query: 131 YDVGGGQQFDDLVSLIEYYRS--FPMVETTGEVLRLIQPFN-ATRIQVRHFHTRVKQLQK 187
           +D+ GG++F  L  L+++Y      + E  G+++ L  P N A     R FH  +   + 
Sbjct: 63  FDLYGGEKFATLAELVQHYTEGRNQLKERNGQMIELKYPLNCADPTNERWFHGHITGKEA 122

Query: 188 E 188
           E
Sbjct: 123 E 123



 Score = 58.0 bits (134), Expect = 7e-07
 Identities = 27/63 (42%), Positives = 39/63 (61%)

Query: 5   RWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVRRGNEVTHIKIQNNGEFLD 64
           RWFH  + G +AEK L++ G +G +L R S S  GD+ LSVR  ++VTH+ I+      D
Sbjct: 111 RWFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQDTKYD 170

Query: 65  LYG 67
           + G
Sbjct: 171 VGG 173


>UniRef50_Q9Y1W9 Cluster: SPTPN6; n=1; Ephydatia fluviatilis|Rep:
           SPTPN6 - Ephydatia fluviatilis
          Length = 229

 Score =  208 bits (507), Expect = 4e-52
 Identities = 99/189 (52%), Positives = 131/189 (69%), Gaps = 7/189 (3%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKK 448
           QE+  II+MTT E+ERG+ KC RYWPDL+ +++  K T+    E++ P Y LR F+V + 
Sbjct: 1   QENSLIIVMTTNEVERGRNKCTRYWPDLDVSKLYGKVTVCCVKETTKPHYVLREFVVNRN 60

Query: 449 DETTV-----KRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVV 503
            E        +RTI+ +HF AWPDH VP +PG VL IL DVN + +++      P   VV
Sbjct: 61  SEDDPAEKEERRTIFQYHFKAWPDHGVPHDPGAVLGILQDVNLQQKELTDEGVKPGPIVV 120

Query: 504 CVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIY 563
             HCSAGIGRTGTFIVID+I D I  +G+DCEIDI +T+Q+VR QRSGMVQ E QYKF+Y
Sbjct: 121 --HCSAGIGRTGTFIVIDVIQDLINHQGWDCEIDIQKTIQLVRSQRSGMVQTEQQYKFVY 178

Query: 564 MAVLEFIET 572
           +A+  F+E+
Sbjct: 179 VAIQHFVES 187


>UniRef50_Q9NKZ9 Cluster: HgPTPN6b protein; n=1; Eptatretus
           burgeri|Rep: HgPTPN6b protein - Eptatretus burgeri
           (Inshore hagfish)
          Length = 243

 Score =  169 bits (411), Expect = 2e-40
 Identities = 87/189 (46%), Positives = 116/189 (61%), Gaps = 6/189 (3%)

Query: 387 IWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVT 446
           I+QE  R+I+MTT+E+ERGKVKC RYWP+L   +      +    E++  +YTLR   + 
Sbjct: 1   IYQEGSRVIVMTTREVERGKVKCVRYWPELGIEKEFGMLRVGLVDETAKQEYTLRELSLQ 60

Query: 447 KKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVH 506
                T  RTI+ + + AWPDH VP + G V+  L +V  R   +      P    V VH
Sbjct: 61  HIGFPTAVRTIWQYQYKAWPDHGVPGDLGEVIEFLDEVAKRQAYL------PEAGPVIVH 114

Query: 507 CSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAV 566
           CSAGIGRTGT IVID++ D I  +G +C IDI   VQ VR QRSG+VQ E+Q++FIY  V
Sbjct: 115 CSAGIGRTGTLIVIDILTDMILHKGPNCSIDIPWVVQWVRSQRSGLVQTESQFRFIYEVV 174

Query: 567 LEFIETEKQ 575
           + FIE  K+
Sbjct: 175 MHFIENLKK 183


>UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3;
           Gallus gallus|Rep: Putative uncharacterized protein -
           Gallus gallus (Chicken)
          Length = 431

 Score =  164 bits (398), Expect = 7e-39
 Identities = 80/146 (54%), Positives = 100/146 (68%), Gaps = 4/146 (2%)

Query: 122 VIIRRKDNKYDVGGGQQFDDLVSLIEYYRSFPMVETTGEVLRLIQPFNATRIQVRHFHTR 181
           V + + D KYDVGGG++FD L  L+E+Y+  PMVE +G V+ L QPFNATRI   +   R
Sbjct: 202 VALLQPDGKYDVGGGERFDTLTDLVEHYKKNPMVEKSGAVVHLKQPFNATRINAANIENR 261

Query: 182 VKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFD 241
           V++L K  +    S   KQGFWEEFE LQ  E   L+ R EG +PEN  KNRYKNI+PFD
Sbjct: 262 VRELNKMAD---HSEKAKQGFWEEFEMLQQQECKLLYPRKEGQRPENKAKNRYKNILPFD 318

Query: 242 HTRVILKDIPPDGPPGSDYINANYIR 267
            TRV L+D+  +  PGSDYINANYI+
Sbjct: 319 TTRVALRDV-DESVPGSDYINANYIK 343



 Score =  101 bits (242), Expect = 5e-20
 Identities = 44/63 (69%), Positives = 53/63 (84%)

Query: 5  RWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVRRGNEVTHIKIQNNGEFLD 64
          RWFHP+++G++AEKLL+  G  G FLARPS SN GDFTLSVRR +EVTHIKIQN G++ D
Sbjct: 3  RWFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGDYYD 62

Query: 65 LYG 67
          LYG
Sbjct: 63 LYG 65



 Score = 86.2 bits (204), Expect = 2e-15
 Identities = 45/120 (37%), Positives = 68/120 (56%), Gaps = 5/120 (4%)

Query: 73  RWYHGQLTAKEAERMMMENGKNGSFLVRESQSQPGDFVLSVRTRDRVTHVIIRRKDNKYD 132
           RW+H  ++  EAE++++  G +GSFL R S+S PGDF LSVR  D VTH+ I+   + YD
Sbjct: 3   RWFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGDYYD 62

Query: 133 VGGGQQFDDLVSLIEYY--RSFPMVETTGEVLRLIQPFNA---TRIQVRHFHTRVKQLQK 187
           + GG++F     L++YY  +   + E    V+ L  P N    T  +  H H   K+ +K
Sbjct: 63  LYGGEKFARKPELVQYYTEQQGLLREKNSNVIELKYPLNCQDPTSERWYHGHLTGKEAEK 122



 Score = 85.4 bits (202), Expect = 4e-15
 Identities = 37/50 (74%), Positives = 43/50 (86%)

Query: 68  DPTTERWYHGQLTAKEAERMMMENGKNGSFLVRESQSQPGDFVLSVRTRD 117
           DPT+ERWYHG LT KEAE+++ E GK GSFLVRESQS+PGDFVLSV T +
Sbjct: 104 DPTSERWYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSVLTNE 153



 Score = 72.1 bits (169), Expect = 4e-11
 Identities = 34/70 (48%), Positives = 47/70 (67%), Gaps = 4/70 (5%)

Query: 339 PNPNYFNTTIPKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMT 398
           P  +Y N    KS  E  +G  + H   K YIATQGCL TT+  FW+M++QE+  +I+MT
Sbjct: 332 PGSDYINANYIKSIPE--DGRNSEHC--KIYIATQGCLQTTVNDFWTMVYQENTHVIVMT 387

Query: 399 TKEIERGKVK 408
           TKE+ERG+V+
Sbjct: 388 TKEVERGRVR 397



 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 24/43 (55%), Positives = 27/43 (62%)

Query: 3   TRRWFHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSV 45
           + RW+H  L G +AEKLL E G  G FL R S S  GDF LSV
Sbjct: 107 SERWYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSV 149


>UniRef50_UPI0000E46C41 Cluster: PREDICTED: similar to the murine
           homolog of receptor-like tyrosine phosphatase gamma
           PTPRG, partial; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to the murine homolog of
           receptor-like tyrosine phosphatase gamma PTPRG, partial
           - Strongylocentrotus purpuratus
          Length = 1529

 Score =  159 bits (385), Expect = 3e-37
 Identities = 82/207 (39%), Positives = 120/207 (57%), Gaps = 14/207 (6%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           K YIATQG L TT   FW ++W++   +I+M TK  ERG+ KC+RYWP     E   +  
Sbjct: 719 KAYIATQGALKTTFDDFWRLVWEQKSVVIVMITKLEERGRRKCDRYWPAKGTPERYNELE 778

Query: 427 ILNEFESSTPDYTLRRFLVT---KKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
           +  E +     YTLR FL+    KK     +R +YHFH+T WPDH VP     VL+ +  
Sbjct: 779 VTLELKEKFASYTLRTFLLKHRHKKHGKVPERRVYHFHYTDWPDHGVPPYTLPVLSFI-- 836

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
                 Q  +  +P     + VHCSAG+GRTGT+IVID +L Q++ E    ++++   ++
Sbjct: 837 ------QRSSAANPTDAGPIIVHCSAGVGRTGTYIVIDTMLKQMQAEE---KVNVFGFLK 887

Query: 544 MVRDQRSGMVQNEAQYKFIYMAVLEFI 570
            +R QR+ +VQ E QY FI+  +LE++
Sbjct: 888 RIRTQRNYLVQTEEQYVFIHDVLLEWL 914



 Score = 54.4 bits (125), Expect = 8e-06
 Identities = 31/66 (46%), Positives = 39/66 (59%), Gaps = 4/66 (6%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF  E+E +Q +     F     S  EN  KNRY NI+ +D +RV L+ +P  G P SDY
Sbjct: 651 GFAAEYEEIQHVPTS--FPATFSSDVENKLKNRYTNIVSYDSSRVSLQPLP--GIPNSDY 706

Query: 261 INANYI 266
           INANYI
Sbjct: 707 INANYI 712



 Score = 44.4 bits (100), Expect = 0.009
 Identities = 45/225 (20%), Positives = 96/225 (42%), Gaps = 30/225 (13%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-------LNKTEV 421
            YI TQ   + T+  FW M+W+ +   I+  T + +  +     YWP        L    +
Sbjct: 1010 YIVTQYPSAETMEDFWKMLWEHNSTTIVTLTDDQKEDE---PIYWPTNVDEPLTLGALTI 1066

Query: 422  V--KKYTILN-----EFESSTPDYTLRRFLVTKKD-ETTVKRTIYHFHFTAWPDHRVPSE 473
               K+ T+++     +F   +   T    ++  K+ +   +  +  +H + WPD   P  
Sbjct: 1067 TLWKRNTLISPSSQGKFLGQSSQGTHTPLVIQNKEFDDDDQLNVRQYHCSYWPDCCSP-- 1124

Query: 474  PGRVLNILLDVNYRLQ---QIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKE 530
                L+   D+ Y +Q   + +  ++      + VH  +G  + GTF  +  +  ++  E
Sbjct: 1125 ----LHTAFDLIYAVQKRNEFLERSNKETVGPITVHDRSGGCQAGTFCALSTLHQEMIHE 1180

Query: 531  GFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQ 575
                 +DI++TV++   +R  ++ +   Y +++ A+      E Q
Sbjct: 1181 E---AVDIYKTVKLYAAKRPNLITSREDYYYLFKALQSCHSAELQ 1222


>UniRef50_Q12913 Cluster: Receptor-type tyrosine-protein phosphatase
            eta precursor; n=32; Mammalia|Rep: Receptor-type
            tyrosine-protein phosphatase eta precursor - Homo sapiens
            (Human)
          Length = 1337

 Score =  158 bits (383), Expect = 4e-37
 Identities = 84/218 (38%), Positives = 125/218 (57%), Gaps = 12/218 (5%)

Query: 357  NGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL 416
            N +P  H   K +IATQG L  T+  FW M+W+++V  IIM TK +E+G+ KCE YWP  
Sbjct: 1098 NYMPGYHS-KKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWPS- 1155

Query: 417  NKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGR 476
             + +     T+    E   P++T+R F V K  +T+    +  FHFT+WPDH VP     
Sbjct: 1156 KQAQDYGDITVAMTSEIVLPEWTIRDFTV-KNIQTSESHPLRQFHFTSWPDHGVPD---- 1210

Query: 477  VLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEI 536
              ++L++  Y ++  M     P ++ + VHCSAG+GRTGTFI ID ++ QI  E     +
Sbjct: 1211 TTDLLINFRYLVRDYM--KQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENEN---TV 1265

Query: 537  DIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
            D++  V  +R  R  MVQ E QY F+   VL+ + ++K
Sbjct: 1266 DVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRSQK 1303



 Score = 43.2 bits (97), Expect = 0.020
 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 14/102 (13%)

Query: 165  IQPFNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGS 224
            I+P  +  I+V +F    K+ Q ++           GF EE+E L+++   Q   +    
Sbjct: 1013 IKPKKSKLIRVENFEAYFKKQQADSNC---------GFAEEYEDLKLVGISQ--PKYAAE 1061

Query: 225  KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
              EN  KNRY N++P+D +RV L           DYINANY+
Sbjct: 1062 LAENRGKNRYNNVLPYDISRVKLS---VQTHSTDDYINANYM 1100


>UniRef50_A7SQN6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 548

 Score =  157 bits (382), Expect = 6e-37
 Identities = 78/204 (38%), Positives = 118/204 (57%), Gaps = 12/204 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           K YIAT G  + T   FW M+W+    I++M TK +E+GKVKC +YWP+ N  E   +  
Sbjct: 96  KKYIATIGPKAETTSDFWRMMWEHKSSIVVMLTKLVEKGKVKCHKYWPEEN--EQYGEII 153

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           +  E +    D+ +R+F + K       R + HF+FT+WPDH VP     +L        
Sbjct: 154 VTLEEKEELADFEIRKFFLRKLSNQMETRMVKHFYFTSWPDHDVPEYATGLLEF------ 207

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
             +++    + P    + VHCSAG+GRTGTFIVID +++QI++E     +D++  V  +R
Sbjct: 208 -WKRVRNSWEGPQSGPITVHCSAGVGRTGTFIVIDAMMEQIKEENL---LDVYSYVSRIR 263

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFI 570
            QR+ MVQ  +QY FI+ A+LE +
Sbjct: 264 AQRNFMVQRPSQYSFIHYALLEAV 287



 Score = 75.8 bits (178), Expect = 3e-12
 Identities = 41/123 (33%), Positives = 71/123 (57%), Gaps = 10/123 (8%)

Query: 450 ETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSA 509
           ET   R I HF +  W +H VP++   +++++ D+    ++ +   D P    V VHCS 
Sbjct: 426 ETGEVRQISHFMYLEWTEHAVPTKLLTIIDLIGDLQKARRKHL---DRP----VVVHCSD 478

Query: 510 GIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEF 569
           G+GRTG F  +   L++++ EG    +D+  T +M+R QR GMV +  QY+  Y A+L +
Sbjct: 479 GVGRTGAFCTLFATLERVKLEGV---LDVFITARMLRTQRPGMVSHLDQYRLCYEAILAY 535

Query: 570 IET 572
           +++
Sbjct: 536 LDS 538



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 7/99 (7%)

Query: 168 FNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPE 227
           F  T I+V++   R+ QL ++  G    M    G   EF+ L      +L D    ++P+
Sbjct: 289 FGDTEIEVQNLRMRLMQLAEKVAGT--GMT---GLEREFQLLNGAVPDELSDFYTATQPK 343

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N +KNRY NI+P +  RV+L  IP      + YINA+Y+
Sbjct: 344 NSKKNRYPNILPCERCRVVLPAIP--DKEDTTYINASYL 380



 Score = 43.2 bits (97), Expect = 0.020
 Identities = 21/39 (53%), Positives = 26/39 (66%), Gaps = 1/39 (2%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N  KNRY NI  +DH+RVIL  +  D    +DYINAN+I
Sbjct: 52  NKPKNRYGNIKAYDHSRVILSSVQGDS-ESTDYINANWI 89



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 3/55 (5%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIM---TTKEIERGKVKCERYWPDLNKTE 420
           +IATQ  L  TI  FW M+W E+V  I+M     + +E G+V+   ++  L  TE
Sbjct: 389 FIATQAPLDNTIEDFWRMVWHEEVFCIVMLCGLNEPLETGEVRQISHFMYLEWTE 443


>UniRef50_A7SWW8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 573

 Score =  155 bits (377), Expect = 2e-36
 Identities = 96/243 (39%), Positives = 134/243 (55%), Gaps = 15/243 (6%)

Query: 357 NGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL 416
           N V T +  N  YIATQG L+ TI  FW MIW+++ R+I+M T  IE+G+ KC  YWP  
Sbjct: 83  NYVDTYNAMN-AYIATQGPLAKTISDFWRMIWEQNCRVIVMITNIIEKGRHKCAMYWPTK 141

Query: 417 N-KTEVVKKYTILNEFESSTPDYTLRRF-LVTKKDET--TVKRTIYHFHFTAWPDHRVPS 472
           N KTE     TI    E +   Y++R F +   KD T  T    +  FHFT WPDH  P 
Sbjct: 142 NRKTENHGPLTITFVQEETFAYYSIRTFEIKPNKDGTHYTQPMMVKQFHFTGWPDHGAP- 200

Query: 473 EPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGF 532
           EPG    +L  +      ++ GT P     + VHCSAG+GR+G FIVID ++ +I   G 
Sbjct: 201 EPGFEFPVLDLIMKSTACVVPGTGP-----LVVHCSAGVGRSGAFIVIDSMIKRIHDNG- 254

Query: 533 DCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDSPRARS 592
             ++DI   +  +R+QR+ +VQ E QY FI+  + E+I      + L  +A +D  R   
Sbjct: 255 --DLDIFNFLAHIRNQRNHLVQEECQYIFIHDTLAEYIACNFV-ISLPIKALKDHVRMMR 311

Query: 593 MPV 595
           MP+
Sbjct: 312 MPI 314



 Score = 94.7 bits (225), Expect = 6e-18
 Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 4/184 (2%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           + +IATQ  L +T   +W MIWQE+ R I+M   E E  K     Y P ++ T     Y 
Sbjct: 392 EAFIATQHPLQSTTMDYWRMIWQENCRSIVMLLSEKEWDKDVFPSYLPAVHDTAHFGDYE 451

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           +  E E++  D+ +R   +    + +V R I HFHF  WP+H  P     VL ++  V  
Sbjct: 452 VTMESETARGDFIIRDLKLISTKDPSVIRQIRHFHFLHWPEHGQPWSGQTVLQLVSKVEE 511

Query: 487 RLQQIMTGTDP-PAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
              ++   +        + VHC+ GIGRTG +  +  +  QI +E     + +++T  + 
Sbjct: 512 WESEVEKNSHQFDIIGPIVVHCNNGIGRTGVYCALHALWQQITQEKL---VSVYQTAWLQ 568

Query: 546 RDQR 549
             QR
Sbjct: 569 GHQR 572



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 26/65 (40%), Positives = 38/65 (58%), Gaps = 4/65 (6%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F+ EFE +   E  +    ++  KPEN  KNR+ N++ +DH+RV+L     D    S YI
Sbjct: 25  FFMEFEGVH--EKNKRLTWVQSQKPENQMKNRFANVVAYDHSRVVLSLTEND--QSSHYI 80

Query: 262 NANYI 266
           NANY+
Sbjct: 81  NANYV 85


>UniRef50_A7RTS6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 625

 Score =  154 bits (373), Expect = 7e-36
 Identities = 92/224 (41%), Positives = 126/224 (56%), Gaps = 17/224 (7%)

Query: 348 IPKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKV 407
           IP S     N +   +  NK +IATQG +S T   FW M+W+     I+M T  +ERGK+
Sbjct: 84  IPGSDYINANFIDGYNHRNK-FIATQGPVSNTFDDFWRMVWEHGCSCIVMVTNIVERGKL 142

Query: 408 KCERYWPDLNKTEVVK-KYTILNEFESSTPDYTLRRFL--VTKKDETTVKRTIYHFHFTA 464
           KC++YWP  N  E  +   T L E E S   Y +R+F   +   D  +  R I  +H+TA
Sbjct: 143 KCQKYWPSANPEEYGRLVVTPLEEEELS--HYVIRKFCIEIANSDVESPAREIVQYHYTA 200

Query: 465 WPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMIL 524
           WPDH VP+    +L         +++I       A  +V VHCSAG+GRTGT+IV+D +L
Sbjct: 201 WPDHGVPTHATSLLAF-------IRRIRNSVSRDAGPIV-VHCSAGVGRTGTYIVLDAML 252

Query: 525 DQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
           DQ+ KEG    +DI   V   R QR+ MVQ EAQY FI+ A++E
Sbjct: 253 DQMSKEG---AVDIFGFVSHTRLQRNMMVQTEAQYIFIHDALME 293



 Score = 93.9 bits (223), Expect = 1e-17
 Identities = 75/237 (31%), Positives = 115/237 (48%), Gaps = 45/237 (18%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV----- 421
           + ++ATQ  L TTI  FW M+W+ +   ++M  K+ E  KV+ ++      KTE+     
Sbjct: 393 EAFLATQAPLETTINDFWRMLWEYESYTVVMLNKDSENIKVRLKQ---TPGKTEIIIVQQ 449

Query: 422 ------VKKYTILNEFESSTPD------YTLRRFLV--TKKDETTVKRTI---------- 457
                 +    +L + +S  PD      Y L    V   ++ E  +KR +          
Sbjct: 450 RFFFLLISPKHVLYQGQSYLPDKGEFVVYGLLMVEVESEERQEGYIKRQLKISNTKSSEV 509

Query: 458 ---YHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRT 514
              +HF +  WP+  VP +   V+++L  +  R QQ  TG  P     + VHCS G GRT
Sbjct: 510 RNVFHFQYEDWPEDGVPQDGKLVIDMLKHI-ARAQQ-QTGNGP-----ITVHCSDGSGRT 562

Query: 515 GTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
           GTF  I + L++++    D  ID+ +TV+ +R QR  MVQ   QYKF Y  V  F+E
Sbjct: 563 GTFCAISIALERVK---LDATIDMFQTVRNLRTQRPIMVQTPEQYKFCYEVVRHFVE 616



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 37/97 (38%), Positives = 54/97 (55%), Gaps = 11/97 (11%)

Query: 171 TRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMEN-LQLFDRMEGSKPENI 229
           T  +V+  H R+K LQ  +    E+   K     EF+ L + ++ ++ FD    S PEN 
Sbjct: 300 TEFKVQDLHDRIKALQSRDPDSGETYIAK-----EFKNLDIGDSDVETFD--SASMPENK 352

Query: 230 RKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            KNR+  ++P+D TRV L   P  G  GSDYINA++I
Sbjct: 353 SKNRFL-VLPYDRTRVKLWPYP--GVLGSDYINASFI 386



 Score = 43.2 bits (97), Expect = 0.020
 Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 19/81 (23%)

Query: 200 QGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPF--------------DHTRV 245
           + F EEF  ++   N   F      K EN  KNRY+NI+                DHTRV
Sbjct: 20  KSFKEEFMCIRTPGN---FSWDHSLKEENKPKNRYQNIVACKLFRLTNPCVNSVDDHTRV 76

Query: 246 ILKDIPPDGPPGSDYINANYI 266
            + ++  DG PGSDYINAN+I
Sbjct: 77  AISEL--DGIPGSDYINANFI 95


>UniRef50_Q4RV19 Cluster: Chromosome 15 SCAF14992, whole genome
            shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 15
            SCAF14992, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1790

 Score =  152 bits (369), Expect = 2e-35
 Identities = 83/203 (40%), Positives = 122/203 (60%), Gaps = 15/203 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-NKTEVVKKYTI 427
            YIATQG L+ T   FW M+W++    ++M T+  E+ +VKC++YWP+   +T  + + T+
Sbjct: 1318 YIATQGPLAETFGDFWRMVWEQRTASVVMMTRLEEKSRVKCDQYWPNRGTETYGMVQVTL 1377

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L+  E +T  + +R F +  K  ++ +R +  F FTAWPDH VP  P   LN L  V   
Sbjct: 1378 LDTMELAT--FCVRTFSL-HKSGSSERREVRQFQFTAWPDHGVPEYPTPFLNFLRRVK-- 1432

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                    +PP    + VHCSAG+GRTG FIVID +L++IR E     +DI+  V ++R 
Sbjct: 1433 ------ACNPPDAGPITVHCSAGVGRTGCFIVIDAMLERIRHER---TVDIYGHVTLMRS 1483

Query: 548  QRSGMVQNEAQYKFIYMAVLEFI 570
            QR+ MVQ E QY FI+ A+LE +
Sbjct: 1484 QRNYMVQTEDQYSFIHEALLEAV 1506



 Score =  150 bits (364), Expect = 9e-35
 Identities = 79/202 (39%), Positives = 117/202 (57%), Gaps = 11/202 (5%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YIATQG L+ T   FW M+W+ +  I++M TK  E G+ KC +YWP   ++   + + + 
Sbjct: 1592 YIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFVVD 1650

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
               E + P Y LR F VT   +    RT+  F FT WP+  VP      ++ +  V+   
Sbjct: 1651 PMAEYNMPQYILREFKVTDARDGQ-SRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTK 1709

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            +Q   G D P    + VHCSAG+GRTG FI + ++L+++R EG    +DI +TV+M+R Q
Sbjct: 1710 EQF--GQDGP----IAVHCSAGVGRTGVFITLSIVLERMRYEG---AVDIFQTVKMLRTQ 1760

Query: 549  RSGMVQNEAQYKFIYMAVLEFI 570
            R  MVQ E +Y+F Y A LE++
Sbjct: 1761 RPAMVQTEDEYQFCYQAALEYL 1782



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 30/64 (46%), Positives = 40/64 (62%), Gaps = 7/64 (10%)

Query: 204  EEFETLQMMENLQL-FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYIN 262
            +E+E++   +        +E +KP    KNRY N+I +DHTRVIL   P DG  G+DYIN
Sbjct: 1252 QEYESIDPSQQFTWEHSNLEVNKP----KNRYANVIAYDHTRVIL--APIDGILGNDYIN 1305

Query: 263  ANYI 266
            ANYI
Sbjct: 1306 ANYI 1309



 Score = 42.3 bits (95), Expect = 0.035
 Identities = 23/41 (56%), Positives = 28/41 (68%), Gaps = 2/41 (4%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            P N  KNR  NI+P++ TRV L+  P  G  GSDYINA+YI
Sbjct: 1545 PCNKFKNRLVNIMPYETTRVCLQ--PIRGLEGSDYINASYI 1583


>UniRef50_O14522 Cluster: Receptor-type tyrosine-protein phosphatase T
            precursor; n=168; Chordata|Rep: Receptor-type
            tyrosine-protein phosphatase T precursor - Homo sapiens
            (Human)
          Length = 1463

 Score =  152 bits (369), Expect = 2e-35
 Identities = 84/200 (42%), Positives = 109/200 (54%), Gaps = 14/200 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YIATQG +  T+  FW MIWQE+   I+M T  +E G+VKC RYWPD   TEV     + 
Sbjct: 979  YIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWPD--DTEVYGDIKVT 1036

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
                    +Y +R F V KK    + R +  FHFT+WPDH VP     +L  +  V +  
Sbjct: 1037 LIETEPLAEYVIRTFTVQKKGYHEI-RELRLFHFTSWPDHGVPCYATGLLGFVRQVKF-- 1093

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
                   +PP    + VHCSAG GRTG FI ID +LD    EG    +DI   V+ +R Q
Sbjct: 1094 ------LNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGV---VDIFNCVRELRAQ 1144

Query: 549  RSGMVQNEAQYKFIYMAVLE 568
            R  +VQ E QY F++ A+LE
Sbjct: 1145 RVNLVQTEEQYVFVHDAILE 1164



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 60/213 (28%), Positives = 100/213 (46%), Gaps = 15/213 (7%)

Query: 363  HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
            H     ++ TQ  L  T+  FW +++  +   ++M   E++  +  C +YWP+  KT   
Sbjct: 1262 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLN-EMDTAQF-CMQYWPE--KTSGC 1317

Query: 423  KKYTILNEFESSTPDYTL--RRFLVTKKDETTVK-RTIYHFHFTAWPDHRVPSEPGRVLN 479
                I  EF S+  D  +  R F +          R + H  +  WP +R  + P +   
Sbjct: 1318 YG-PIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYR-DTPPSK--R 1373

Query: 480  ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
             LL V  RL++     D      V VHC  G GR+GTF  I  + + I+++     ID+ 
Sbjct: 1374 SLLKVVRRLEKWQEQYDGREGRTV-VHCLNGGGRSGTFCAICSVCEMIQQQNI---IDVF 1429

Query: 540  RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
              V+ +R+ +S MV+   QYKF+Y   LE++ +
Sbjct: 1430 HIVKTLRNNKSNMVETLEQYKFVYEVALEYLSS 1462



 Score = 54.8 bits (126), Expect = 6e-06
 Identities = 33/66 (50%), Positives = 41/66 (62%), Gaps = 5/66 (7%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF EE+E L   +    +D  +  + EN  KNRY NII +DH+RV L  +  DG P SDY
Sbjct: 910 GFKEEYEALPEGQTAS-WDTAK--EDENRNKNRYGNIISYDHSRVRL--LVLDGDPHSDY 964

Query: 261 INANYI 266
           INANYI
Sbjct: 965 INANYI 970


>UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphatase
            delta precursor; n=183; Eumetazoa|Rep: Receptor-type
            tyrosine-protein phosphatase delta precursor - Homo
            sapiens (Human)
          Length = 1912

 Score =  152 bits (369), Expect = 2e-35
 Identities = 81/204 (39%), Positives = 118/204 (57%), Gaps = 11/204 (5%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG L+ T   FW M+W+ +  I++M TK  E G+ KC +YWP   ++   + + 
Sbjct: 1712 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFV 1770

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +    E + P Y LR F VT   +    RT+  F FT WP+  VP      ++ +  V+ 
Sbjct: 1771 VDPMAEYNMPQYILREFKVTDARDGQ-SRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHK 1829

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
              +Q   G D P    + VHCSAG+GRTG FI + ++L+++R EG    +DI +TV+M+R
Sbjct: 1830 TKEQF--GQDGP----ISVHCSAGVGRTGVFITLSIVLERMRYEGV---VDIFQTVKMLR 1880

Query: 547  DQRSGMVQNEAQYKFIYMAVLEFI 570
             QR  MVQ E QY+F Y A LE++
Sbjct: 1881 TQRPAMVQTEDQYQFSYRAALEYL 1904



 Score =  151 bits (366), Expect = 5e-35
 Identities = 86/203 (42%), Positives = 123/203 (60%), Gaps = 15/203 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-NKTEVVKKYTI 427
            YIATQG L  T   FW MIW++    ++M TK  ER +VKC++YWP    +T  + + T+
Sbjct: 1425 YIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTL 1484

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L+  E +T  Y +R F +  K+ ++ KR +  F FTAWPDH VP  P   L         
Sbjct: 1485 LDTVELAT--YCVRTFAL-YKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAF------- 1534

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
            L+++ T  +PP    + VHCSAG+GRTG FIVID +L++I+ E     +DI+  V ++R 
Sbjct: 1535 LRRVKT-CNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEK---TVDIYGHVTLMRA 1590

Query: 548  QRSGMVQNEAQYKFIYMAVLEFI 570
            QR+ MVQ E QY FI+ A+LE +
Sbjct: 1591 QRNYMVQTEDQYIFIHDALLEAV 1613



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 29/66 (43%), Positives = 42/66 (63%), Gaps = 7/66 (10%)

Query: 202  FWEEFETLQMMENLQL-FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
            F +E+E++   +        +E +KP    KNRY N+I +DH+RV+L  I  +G PGSDY
Sbjct: 1357 FSQEYESIDPGQQFTWEHSNLEVNKP----KNRYANVIAYDHSRVLLSAI--EGIPGSDY 1410

Query: 261  INANYI 266
            +NANYI
Sbjct: 1411 VNANYI 1416



 Score = 41.5 bits (93), Expect = 0.062
 Identities = 22/41 (53%), Positives = 28/41 (68%), Gaps = 2/41 (4%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            P N  KNR  NI+P++ TRV L+  P  G  GSDYINA++I
Sbjct: 1667 PCNKFKNRLVNIMPYESTRVCLQ--PIRGVEGSDYINASFI 1705


>UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphatase S
            precursor; n=34; Craniata|Rep: Receptor-type
            tyrosine-protein phosphatase S precursor - Homo sapiens
            (Human)
          Length = 1948

 Score =  152 bits (368), Expect = 3e-35
 Identities = 80/204 (39%), Positives = 118/204 (57%), Gaps = 11/204 (5%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG L+ T   FW M+W+ +  I++M TK  E G+ KC +YWP   ++   + + 
Sbjct: 1748 KAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFV 1806

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +    E + P Y LR F VT   +    RT+  F FT WP+  VP      ++ +  V+ 
Sbjct: 1807 VDPMAEYNMPQYILREFKVTDARDGQ-SRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHK 1865

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
              +Q   G D P    + VHCSAG+GRTG FI + ++L+++R EG    +DI +TV+M+R
Sbjct: 1866 TKEQF--GQDGP----ISVHCSAGVGRTGVFITLSIVLERMRYEGV---VDIFQTVKMLR 1916

Query: 547  DQRSGMVQNEAQYKFIYMAVLEFI 570
             QR  MVQ E +Y+F Y A LE++
Sbjct: 1917 TQRPAMVQTEDEYQFCYQAALEYL 1940



 Score =  147 bits (355), Expect = 1e-33
 Identities = 81/203 (39%), Positives = 123/203 (60%), Gaps = 15/203 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-NKTEVVKKYTI 427
            YIATQG L  T   FW M+W++    I+M T+  E+ ++KC++YWP+   +T    + T+
Sbjct: 1461 YIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTL 1520

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L+  E +T  + +R F +  K+ ++ KR +  F FTAWPDH VP  P   L         
Sbjct: 1521 LDTIELAT--FCVRTFSL-HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAF------- 1570

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
            L+++ T  +PP    + VHCSAG+GRTG FIVID +L++I+ E     +D++  V ++R 
Sbjct: 1571 LRRVKT-CNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEK---TVDVYGHVTLMRS 1626

Query: 548  QRSGMVQNEAQYKFIYMAVLEFI 570
            QR+ MVQ E QY FI+ A+LE +
Sbjct: 1627 QRNYMVQTEDQYSFIHEALLEAV 1649



 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 24/39 (61%), Positives = 30/39 (76%), Gaps = 2/39 (5%)

Query: 228  NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            N  KNRY N+I +DH+RVIL+  P +G  GSDYINANY+
Sbjct: 1416 NKPKNRYANVIAYDHSRVILQ--PIEGIMGSDYINANYV 1452



 Score = 41.5 bits (93), Expect = 0.062
 Identities = 22/41 (53%), Positives = 28/41 (68%), Gaps = 2/41 (4%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            P N  KNR  NI+P++ TRV L+  P  G  GSDYINA++I
Sbjct: 1703 PCNKFKNRLVNIMPYESTRVCLQ--PIRGVEGSDYINASFI 1741


>UniRef50_Q4SAP1 Cluster: Chromosome undetermined SCAF14681, whole
            genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF14681, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1751

 Score =  151 bits (367), Expect = 4e-35
 Identities = 81/204 (39%), Positives = 118/204 (57%), Gaps = 11/204 (5%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG L+ T   FW M+W+ +  I++M TK  E G+ KC +YWP   ++   + + 
Sbjct: 1551 KAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFV 1609

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +    E + P Y LR F VT   +    RT+  F FT WP+  VP      ++ +  V+ 
Sbjct: 1610 VDPMAEYNMPQYILREFKVTDARDGQ-SRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHK 1668

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
              +Q   G D P    + VHCSAG+GRTG FI + ++L+++R EG    +DI +TV+M+R
Sbjct: 1669 TKEQF--GQDGP----ISVHCSAGVGRTGVFITLSIVLERMRYEGV---VDIFQTVKMLR 1719

Query: 547  DQRSGMVQNEAQYKFIYMAVLEFI 570
             QR  MVQ E QY+F Y A LE++
Sbjct: 1720 TQRPAMVQTEDQYQFCYRAGLEYL 1743



 Score =  133 bits (321), Expect = 1e-29
 Identities = 87/226 (38%), Positives = 119/226 (52%), Gaps = 37/226 (16%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLN-KTEVVKKYTI 427
            YIATQG L  T   FW MIW++    I+M TK  ER +VKC++YWP    +T  + + T+
Sbjct: 1240 YIATQGALPETFGEFWRMIWEQRSANIVMMTKLEERSRVKCDQYWPTRGTETYGLIQVTL 1299

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTV-----------------------KRTIYHFHFTA 464
            L+  E +T  Y +R F + K    ++                       KR +  F FTA
Sbjct: 1300 LDTVELAT--YCVRTFALFKVGSASISRYSEGSEADHSPVLLLQNGSSEKREVRQFQFTA 1357

Query: 465  WPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMIL 524
            WPDH VP  P   L  L  V           +PP    + VHCSAG+GRTG FIVID +L
Sbjct: 1358 WPDHGVPEHPTLFLAFLRRVK--------ACNPPDAGPMVVHCSAGVGRTGCFIVIDAML 1409

Query: 525  DQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
            ++I+ E     +DI+  V ++R QR+ MVQ E QY FI+ A+LE +
Sbjct: 1410 ERIKHEK---TVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAV 1452



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 31/66 (46%), Positives = 42/66 (63%), Gaps = 7/66 (10%)

Query: 202  FWEEFETLQMMENLQL-FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
            F +E+E++   +        +E +KP    KNRY N+I +DH+RV+L  I  DG PGSDY
Sbjct: 1172 FSQEYESIDPGQQFTWEHSNLEVNKP----KNRYANVIAYDHSRVLLSAI--DGVPGSDY 1225

Query: 261  INANYI 266
            INANYI
Sbjct: 1226 INANYI 1231



 Score = 41.5 bits (93), Expect = 0.062
 Identities = 22/41 (53%), Positives = 28/41 (68%), Gaps = 2/41 (4%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            P N  KNR  NI+P++ TRV L+  P  G  GSDYINA++I
Sbjct: 1506 PCNKFKNRLVNIMPYESTRVCLQ--PIRGVEGSDYINASFI 1544


>UniRef50_UPI0000DB76E9 Cluster: PREDICTED: similar to protein
            tyrosine phosphatase, receptor type, K precursor; n=1;
            Apis mellifera|Rep: PREDICTED: similar to protein
            tyrosine phosphatase, receptor type, K precursor - Apis
            mellifera
          Length = 1957

 Score =  151 bits (366), Expect = 5e-35
 Identities = 84/202 (41%), Positives = 109/202 (53%), Gaps = 15/202 (7%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG  + TI  FW MIWQE+  II M  K IE GK KCE+YWPD+ K +      
Sbjct: 1469 KFYIATQGPKANTIIDFWRMIWQEESYIICMIAKLIEDGKTKCEQYWPDIGKKKRYGDII 1528

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            + N   +   D+T R   VT  DE    R I H H+TAWPDH  P     V      V Y
Sbjct: 1529 VFNAKHAVFADFTFRTLHVTYGDEA---RKIEHLHYTAWPDHGAPLFTHSV------VTY 1579

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
              + + T   PP    V VHCSAG+GRTG  I+ D+ L +   EG    +++    Q +R
Sbjct: 1580 LKKLLAT---PPGSGPVVVHCSAGVGRTGIVILCDICLRRAAAEG---AVNVFSETQAIR 1633

Query: 547  DQRSGMVQNEAQYKFIYMAVLE 568
            +QR  M+ N+ QY F ++ +LE
Sbjct: 1634 NQRINMIDNKQQYLFAHLTLLE 1655



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 24/45 (53%), Positives = 30/45 (66%), Gaps = 2/45 (4%)

Query: 223  GSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
            G   +N  KNRY N+I +D  RVIL+ +P D  P SDYINA YI+
Sbjct: 1421 GKLEQNRGKNRYGNLIAYDENRVILEKLPDD--PYSDYINATYIK 1463



 Score = 43.6 bits (98), Expect = 0.015
 Identities = 47/206 (22%), Positives = 90/206 (43%), Gaps = 17/206 (8%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK-KYTI 427
            YIATQ  L  T   FW MI +  V +IIM    ++   +K     P + K E     Y  
Sbjct: 1757 YIATQLPLPETFSDFWRMIAEYKVELIIM----LQLPDLKDATCCPIVPKREFKPVPYIN 1812

Query: 428  LNEFESSTPD-YTLRRFLVTKKDE-TTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            +   E ST + YTL + ++    E    ++ +     T W   +    P  +  + L   
Sbjct: 1813 VRTKEFSTFEYYTLEKLIIVDNSEKPATEQYVTILCSTEWKTGKNQDLPATMSLVTL--- 1869

Query: 486  YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
            ++  Q +   D P    + V C  G+   G ++ ++ +L+++  E    E D+   V+ +
Sbjct: 1870 WQSAQKILKEDSP----IVVVCHDGVTGCGLYLALNFLLERMIIEK---ECDVCFAVRAI 1922

Query: 546  RDQRSGMVQNEAQYKFIYMAVLEFIE 571
            R  R   + +    +++Y A++ +++
Sbjct: 1923 RKSRPDFITSLEHMEYLYDAIITYLK 1948


>UniRef50_Q4SFF7 Cluster: Chromosome 1 SCAF14603, whole genome shotgun
            sequence; n=2; Tetraodontidae|Rep: Chromosome 1
            SCAF14603, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1843

 Score =  151 bits (366), Expect = 5e-35
 Identities = 80/204 (39%), Positives = 118/204 (57%), Gaps = 11/204 (5%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG L+ T   FW M+W+ +  I++M TK  E G+ KC +YWP   ++   + + 
Sbjct: 1643 KAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFV 1701

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +    E + P Y LR F VT   +    RT+  F FT WP+  VP      ++ +  V+ 
Sbjct: 1702 VDPMAEYNMPQYILREFKVTDARDGQ-SRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHK 1760

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
              +Q   G D P    + VHCSAG+GRTG FI + ++L+++R EG    +DI +TV+M+R
Sbjct: 1761 TKEQF--GQDGP----ISVHCSAGVGRTGVFITLSIVLERMRYEGV---VDIFQTVKMLR 1811

Query: 547  DQRSGMVQNEAQYKFIYMAVLEFI 570
             QR  MVQ E +Y+F Y A LE++
Sbjct: 1812 TQRPAMVQTEDEYQFCYHAALEYL 1835



 Score = 88.2 bits (209), Expect = 5e-16
 Identities = 48/140 (34%), Positives = 77/140 (55%), Gaps = 12/140 (8%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-NKTEVVKKYTI 427
            YIATQG L  T   FW M+W++    ++M T+  E+ ++KC++YWP    +T  + + T+
Sbjct: 1197 YIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRIKCDQYWPSRGTETYGMTQVTL 1256

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L+  E +T  + +R F +  K+ ++ KR +  F FTAWPDH VP  P   L         
Sbjct: 1257 LDTIELAT--FCVRTFSL-HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAF------- 1306

Query: 488  LQQIMTGTDPPAQAVVCVHC 507
            L+++ T  +PP    +  HC
Sbjct: 1307 LRRVKT-CNPPDAGPIIAHC 1325



 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 33/64 (51%), Positives = 46/64 (71%), Gaps = 3/64 (4%)

Query: 507  CSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAV 566
            CSAG+GRTG FIVID +L++I+ E     +DI+  V ++R QR+ MVQ E QY FI+ A+
Sbjct: 1484 CSAGVGRTGCFIVIDAMLERIKHEK---TVDIYGHVTLMRSQRNYMVQTEDQYSFIHDAL 1540

Query: 567  LEFI 570
            LE +
Sbjct: 1541 LEAV 1544



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 9/109 (8%)

Query: 165  IQPFNATR-IQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFD---- 219
            I P + T  +++R  + +   +      PI  +A      +  + L++ +  +  D    
Sbjct: 1082 ITPHHPTDPVEMRRINFQTPGMMNHPPIPISELAEHTELLKANDNLKLSQEYESIDPGQQ 1141

Query: 220  -RMEGSKPE-NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
               E S  E N  KNRY N+I +DH+RVIL   P DG  GSDYINANYI
Sbjct: 1142 FTWEHSNLEVNKPKNRYANVIAYDHSRVIL--APIDGITGSDYINANYI 1188



 Score = 41.1 bits (92), Expect = 0.082
 Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 8/96 (8%)

Query: 171  TRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIR 230
            T +  R  ++ +++L +     +ES  +  G   EF+ L   +       +  + P N  
Sbjct: 1549 TEVAARSLYSYIQKLAQ-----VESGEHVTGMELEFKRLANSK-AHTSRFISANLPCNKF 1602

Query: 231  KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            KNR  NI+P++ TRV L+  P  G  GSDYINA++I
Sbjct: 1603 KNRLVNIMPYETTRVCLQ--PIRGLEGSDYINASFI 1636


>UniRef50_UPI0001554856 Cluster: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 22
           (Hematopoietic cell protein-tyrosine phosphatase
           70Z-PEP) (Lymphoid phosphatase) (LyP); n=1;
           Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 22
           (Hematopoietic cell protein-tyrosine phosphatase
           70Z-PEP) (Lymphoid phosphatase) (LyP) - Ornithorhynchus
           anatinus
          Length = 800

 Score =  151 bits (365), Expect = 7e-35
 Identities = 80/203 (39%), Positives = 111/203 (54%), Gaps = 12/203 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKKY 425
           + YIATQG LSTT+  FW MIW+  V II+M   E E GK KCERYWP+L +T +    +
Sbjct: 189 RAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEFEMGKKKCERYWPELGETVLQFGPF 248

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
           +I  E E    DY +R        ET   RTIY FH+  WPDH VPS     ++ +L++ 
Sbjct: 249 SISCEAEEKKSDYVVRTLKAKLYSET---RTIYQFHYKNWPDHDVPSS----IDPILELI 301

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
           + ++      + P    +C+HCSAG GRTG    ID     ++        +I   +Q +
Sbjct: 302 WEMRCYQEDDNVP----ICIHCSAGCGRTGVICAIDYTWKLLKDGIIPVNFNIFSLIQEM 357

Query: 546 RDQRSGMVQNEAQYKFIYMAVLE 568
           R QR  +VQ + QY+ +Y AV E
Sbjct: 358 RTQRPSLVQTQEQYELVYNAVTE 380



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 27/43 (62%), Positives = 33/43 (76%), Gaps = 2/43 (4%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           KPENI+KNRYK+I+PFDH+RV L  I  D    S YINAN+I+
Sbjct: 143 KPENIKKNRYKDILPFDHSRVELSLITSD--EDSYYINANFIK 183


>UniRef50_UPI0000E49AED Cluster: PREDICTED: similar to protein
            tyrosine phosphatase precursor, partial; n=5;
            Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
            protein tyrosine phosphatase precursor, partial -
            Strongylocentrotus purpuratus
          Length = 4520

 Score =  151 bits (365), Expect = 7e-35
 Identities = 77/207 (37%), Positives = 116/207 (56%), Gaps = 8/207 (3%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG L  TI  FW M+W+     I+M T  +E GK KCE YWP   + ++    T
Sbjct: 4322 KKYIATQGPLPNTIEHFWEMVWENQTSTIVMMTALVEGGKTKCEHYWPAGEEPQLHGNVT 4381

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +     + T ++ + R L+ +K+ T  +RT+ H+ + AW DH VP     ++ +L  V  
Sbjct: 4382 VTLVGSNQTDNF-IERTLLLEKEGT--ERTVTHYQYLAWTDHGVPESTAPLVGLLRQVKV 4438

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
              Q+    T P     + VHCSAG+GRTGTFI  DM++D I++      ID+  T+  +R
Sbjct: 4439 TNQEDGAATGP-----IVVHCSAGVGRTGTFIAADMLMDAIQRSTATDYIDVAGTIAKIR 4493

Query: 547  DQRSGMVQNEAQYKFIYMAVLEFIETE 573
            +QR+ +VQ   QY +++  VL  IE +
Sbjct: 4494 EQRALLVQTLYQYIYLHRTVLSLIEEQ 4520



 Score = 54.4 bits (125), Expect = 8e-06
 Identities = 29/69 (42%), Positives = 43/69 (62%), Gaps = 7/69 (10%)

Query: 201  GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
            GF +E+  L  ME  +       ++ ++  KNRY+NI+P+D+TRV LK     G  G+DY
Sbjct: 4257 GFSDEYNNLPAMEKTRAVTAARQARNDD--KNRYRNILPYDYTRVQLK-----GVAGTDY 4309

Query: 261  INANYIRCD 269
            INA+YI+ D
Sbjct: 4310 INASYIKDD 4318


>UniRef50_Q4SH31 Cluster: Chromosome 8 SCAF14587, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 8 SCAF14587, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1108

 Score =  150 bits (364), Expect = 9e-35
 Identities = 85/220 (38%), Positives = 125/220 (56%), Gaps = 15/220 (6%)

Query: 349 PKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVK 408
           P S     N +   H  N  +IATQG +  T+Y FW M+WQE+   I+M TK +E G+VK
Sbjct: 613 PNSDYINANYIDGYHRSNH-FIATQGPMEETLYDFWRMVWQENCFSIVMITKLVEVGRVK 671

Query: 409 CERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDH 468
           C +YWPD ++     K T+L     +  +YT+R F + ++  +T K  +  FHFT+WP+H
Sbjct: 672 CCKYWPDDSEMYGDIKITLLK--TETLAEYTVRTFALERRGYST-KHEVRQFHFTSWPEH 728

Query: 469 RVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIR 528
            VP     +L         ++++   T P A  VV VHCS G GRTG +IV+D++LD   
Sbjct: 729 GVPYHATGLLAF-------IRRVKASTPPDAGPVV-VHCSVGAGRTGCYIVLDVMLDMAE 780

Query: 529 KEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
            EG    +DI+  V+ +  +R  M+Q E QY FI+ A+LE
Sbjct: 781 CEGV---VDIYNCVKTLCSRRINMIQTEEQYVFIHDAILE 817



 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 46/193 (23%), Positives = 86/193 (44%), Gaps = 20/193 (10%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKV-KCERYWPDLNKTEVVKKYTI 427
            +I T   L  T   FW +++      ++M  +  +      C +YWP+      +++Y  
Sbjct: 921  FIVTPHPLPGTTADFWRLVFDYGCTAVVMLNQLNQSNSAWPCVQYWPEPG----LQQYGP 976

Query: 428  LN-EFESSTPDYTLRRFLVTKKDETTVKR---TIYHFHFTAWPDHR-VPSEPGRVLNILL 482
            +  EF S + D  +   L   K+ T ++     +  F F  W  +R VP      LN+L 
Sbjct: 977  MEVEFLSMSADEDVVTRLFRVKNVTRLQEGQLVVCQFQFLRWSAYRDVPDSKKAFLNLLA 1036

Query: 483  DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
             V+   ++   G          VHC  G GR+G+F   +++L+ I+ +     +DI   V
Sbjct: 1037 QVHKWQRECGEGR-------TVVHCLNGGGRSGSFCACNILLEMIQYQNM---VDIFYAV 1086

Query: 543  QMVRDQRSGMVQN 555
            + +R+ +  MV++
Sbjct: 1087 KTLRNCKPNMVES 1099


>UniRef50_Q9BI03 Cluster: Receptor protein tyrosine phosphatase;
           n=2; Metazoa|Rep: Receptor protein tyrosine phosphatase
           - Geodia cydonium (Sponge)
          Length = 999

 Score =  150 bits (364), Expect = 9e-35
 Identities = 86/214 (40%), Positives = 114/214 (53%), Gaps = 12/214 (5%)

Query: 365 YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
           +   +IATQG L  TI  FW ++WQE    I+M T   E  K+KC++YWP+ + T+    
Sbjct: 508 FRNKFIATQGPLPKTIVDFWRLVWQEKPPTIVMVTNLKEGTKIKCQQYWPE-SGTKNFGP 566

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
           + I    E +  DYT R  LV  K  +     +  FHFTAWPDH VP     +L      
Sbjct: 567 FEITISEEQTLADYTTRTLLVQLKGSSECPLKVTQFHFTAWPDHGVPDYATPIL--AFHK 624

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
             R Q        P++  + +HCSAG+GRTGT I ID +LDQI KE     +DI   +Q 
Sbjct: 625 KIRKQH------RPSKGPLLMHCSAGVGRTGTLITIDRVLDQIAKERV---VDIAGVIQH 675

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVG 578
           +R QR  MVQN  QY FI  A+LE I     ++G
Sbjct: 676 LRGQRMKMVQNPEQYIFINDAILEAITCGDTQIG 709



 Score = 91.5 bits (217), Expect = 6e-17
 Identities = 60/223 (26%), Positives = 108/223 (48%), Gaps = 16/223 (7%)

Query: 354 ETENGVPTVHV----YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKC 409
           ETE+ +  V V      + +I  Q  + +T   FW M++     +I+M    +E GK  C
Sbjct: 779 ETEDYIHAVAVNGYKQQRAFIIAQSPMQSTARDFWKMVYDRKCGVIVMLCDLVESGKEAC 838

Query: 410 ERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHR 469
            +YWP  +  + V ++TI    E     +TLR F V  K +T     +   +   W    
Sbjct: 839 YKYWPS-SGVQHVGEFTIDILGEEELEGFTLRTFGVLHK-KTNKSHQVQQIYIQGWAPDG 896

Query: 470 VPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRK 529
             S  G +  ++ +V  ++QQ  TG +P     + VHCS  + R+G F  I   +++ + 
Sbjct: 897 QCSNLGSITAVIAEVT-KIQQ-RTGNNP-----ILVHCSDTVNRSGMFCAIATTIERCKT 949

Query: 530 EGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
           EG    +D+ + V+ +R Q+ G V++  QY  ++  VL ++++
Sbjct: 950 EGV---VDVFQVVKALRVQKPGAVRSVMQYHSLFETVLVYLDS 989



 Score = 34.3 bits (75), Expect = 9.4
 Identities = 15/44 (34%), Positives = 25/44 (56%)

Query: 223 GSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           G+ PE    NR+ NI  +D+ R++L+ +        D+INA Y+
Sbjct: 460 GTSPELKLLNRFGNITVYDNNRIVLRPLEGHADCQRDFINACYV 503


>UniRef50_Q9I8F1 Cluster: CD45 precursor; n=4; Tetraodontidae|Rep:
           CD45 precursor - Fugu rubripes (Japanese pufferfish)
           (Takifugu rubripes)
          Length = 1246

 Score =  150 bits (363), Expect = 1e-34
 Identities = 82/211 (38%), Positives = 120/211 (56%), Gaps = 15/211 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK-TEVVKKY 425
           K YIA QG    T+  FW MIW++   II+M ++  E  ++KC +YWP  ++ TE+ +++
Sbjct: 686 KKYIAAQGPKEETVSNFWRMIWEQQTSIIVMVSRCEEGNRIKCAQYWPSEDRDTEIFEEF 745

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            +    E   PDY +R   +T K +   +R + H  F +WPDH VP E   +L +   VN
Sbjct: 746 IVKLTSEDHYPDYIIRHLSLTNKKDKGSEREVTHIQFMSWPDHGVPEEAQLLLKLRRRVN 805

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
              +   +G        + VHCSAG+GRTGT+I ID +++ +  EG    +DI+  V M+
Sbjct: 806 -SFKNFFSGP-------IVVHCSAGVGRTGTYIGIDAMMESLEAEG---RVDIYGYVVML 854

Query: 546 RDQRSGMVQNEAQYKFIYMAVLE---FIETE 573
           R QR  MVQ EAQY  I+ A+LE   F ETE
Sbjct: 855 RRQRCLMVQVEAQYILIHQALLEHTQFGETE 885



 Score =  101 bits (241), Expect = 7e-20
 Identities = 59/199 (29%), Positives = 103/199 (51%), Gaps = 13/199 (6%)

Query: 368  TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI 427
            T+I+ Q  L  T+  FWSMI Q+ V I++M + +  +G   C  YW +  KT  V+   +
Sbjct: 999  TFISAQTPLPDTVADFWSMILQKRVSIVVMLS-DCSQGDEDCV-YWGEDKKT--VEDIEV 1054

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
              E   ++P++ LR  ++    +T   + + HF F  W D  VP +P  + +++ ++ +R
Sbjct: 1055 ETESTDNSPNFILRNMMIHHL-KTDAHQQVKHFQFLKWGDKEVPEKPQDLADLIKEIKHR 1113

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                  G   P    + VHC+ G  R+G F  +  +LD   KE     +D+ + V+ +R 
Sbjct: 1114 -----CGYTWPRSTPIIVHCNDGSSRSGAFCALWNLLDNAEKEKM---VDVFQVVKTLRK 1165

Query: 548  QRSGMVQNEAQYKFIYMAV 566
            +R GM  +  QY+F+Y A+
Sbjct: 1166 ERQGMCPSLEQYQFLYDAL 1184



 Score = 44.8 bits (101), Expect = 0.007
 Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 4/65 (6%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F  EF+++  +     +   E  K  N+ KNRY +I+P+D+ RV L     +G  G DYI
Sbjct: 619 FLAEFQSIPRI--FSKYTVKEAKKSHNVPKNRYVDILPYDYNRVQL--TTGNGSAGCDYI 674

Query: 262 NANYI 266
           NA++I
Sbjct: 675 NASFI 679



 Score = 42.3 bits (95), Expect = 0.035
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 14/91 (15%)

Query: 204 EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVIL-----KDIPPDGPPGS 258
           +EFE L   +N + F+   G   EN +KNR  ++IP+D+ RV+L     K    D  P  
Sbjct: 912 DEFERLPNFKNWRTFNT--GVTEENKKKNRTSSVIPYDYNRVLLKLDEEKSHESDPDPDD 969

Query: 259 DYINANYIRCDSMDSISDSQEFTGNGSTENG 289
           DY  ++Y      D I DS ++  N S  +G
Sbjct: 970 DYDTSSY------DDIEDSAKYI-NASLLSG 993


>UniRef50_UPI0000F1E754 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 901

 Score =  149 bits (361), Expect = 2e-34
 Identities = 80/210 (38%), Positives = 121/210 (57%), Gaps = 12/210 (5%)

Query: 363 HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
           ++  K +IA QG L  T+  FW +IW+++V  I+M TK  E+G+VKCE YWP   KT   
Sbjct: 669 YITKKEFIAAQGPLPGTVNDFWRLIWEKNVHTIVMLTKCNEQGRVKCEEYWPAEMKT--F 726

Query: 423 KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
              T+    +    D+TLR F V K  +T   R++ HFHFTAWPDH VP        +L+
Sbjct: 727 SNLTVTTISDIPLEDWTLRDFEV-KNMKTAEIRSVRHFHFTAWPDHGVP----ETTELLI 781

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
           +  + +++ M   +    +   VHCSAG+GRTGTFI ID ++ QI ++G    +D++  +
Sbjct: 782 NFRHLVREHM--DEYSRHSPTLVHCSAGVGRTGTFIAIDRLIFQIERDGV---VDVYGII 836

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
             +R  R  MVQ E QY F+    ++ I++
Sbjct: 837 HDLRMHRPLMVQTEDQYVFLNQCAMDIIKS 866



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 29/66 (43%), Positives = 38/66 (57%), Gaps = 5/66 (7%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF EEFE L+ +   Q   +     PEN  KNRY N++P+D +RV L  +     P  DY
Sbjct: 606 GFAEEFEDLRPVGINQ--SKTVAVFPENKAKNRYNNVLPYDSSRVKLSVL---SSPFDDY 660

Query: 261 INANYI 266
           INANY+
Sbjct: 661 INANYM 666


>UniRef50_O44328 Cluster: Receptor tyrosine phosphatase; n=6;
            Eumetazoa|Rep: Receptor tyrosine phosphatase - Hirudo
            medicinalis (Medicinal leech)
          Length = 2051

 Score =  149 bits (361), Expect = 2e-34
 Identities = 81/210 (38%), Positives = 122/210 (58%), Gaps = 15/210 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK-KYTI 427
            YIATQG ++ T   FW M+W+    +I+M TK  ERG+VKC++YWP          +  +
Sbjct: 1557 YIATQGPMAETSVDFWRMVWERQSPVIVMMTKLEERGRVKCDQYWPSRGSESYGSLQVNL 1616

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            ++  E +T  YT+R F ++  +  + KR + HF FTAWPD+ VP     +L     + + 
Sbjct: 1617 VDVIELAT--YTMRTFQMS-SEFNSEKREVRHFQFTAWPDYGVPEHAAPLL-----LFHE 1668

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
              Q+    DPP    + VHCSAG+GRTG F+V+D +L++I+  G    +DI+  V  +R 
Sbjct: 1669 EGQV---HDPPDSGPIVVHCSAGVGRTGVFVVLDSMLERIKHTG---SVDIYGHVTCLRA 1722

Query: 548  QRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
            QR+ MVQ E QY FI+ A+LE + +    V
Sbjct: 1723 QRNYMVQTEDQYIFIHAAILEAVTSGNTEV 1752



 Score =  147 bits (355), Expect = 1e-33
 Identities = 78/207 (37%), Positives = 117/207 (56%), Gaps = 13/207 (6%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            Y + YIATQG L  T+  FW  +W+ +  II+M TK  E G+  C +YWP  ++     +
Sbjct: 1849 YRRAYIATQGPLPDTVEDFWRALWESNCNIIVMLTKLREMGREMCHQYWP--SERSARYQ 1906

Query: 425  YTILNEF-ESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
            Y +++   E + P Y LR F VT   +    RT+  F  T WP+  VPS     ++ +  
Sbjct: 1907 YFVVDPLAEYNMPQYILREFKVTDARDGQ-SRTMRQFQLTDWPEQGVPSTGDGFIDFIGQ 1965

Query: 484  VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
             +   +Q   G + P    + VHCSAG+GRTG FI + ++L+++R EG    +D+ +TV 
Sbjct: 1966 THKTKEQF--GQEGP----IAVHCSAGVGRTGVFITLSIVLERMRFEG---AVDVFQTVN 2016

Query: 544  MVRDQRSGMVQNEAQYKFIYMAVLEFI 570
            ++R QR GMVQ E QY F Y A LE++
Sbjct: 2017 VLRTQRPGMVQTEEQYAFCYRAALEYL 2043



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 24/48 (50%), Positives = 30/48 (62%), Gaps = 9/48 (18%)

Query: 228  NIRKNRYKNIIPFDHTRVILKDIP-------PDGP--PGSDYINANYI 266
            N  KNRY N+I +DH+RV L  +P       P G   PGSDYINAN++
Sbjct: 1501 NKSKNRYANVIAYDHSRVTLHPLPQASSTYHPPGQVVPGSDYINANFL 1548



 Score = 41.5 bits (93), Expect = 0.062
 Identities = 20/39 (51%), Positives = 28/39 (71%), Gaps = 2/39 (5%)

Query: 228  NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            N +KNR  N++P++ TRV L+  P  G  GSDYINA++I
Sbjct: 1808 NKQKNRLVNVLPYETTRVCLQ--PIRGVDGSDYINASFI 1844


>UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor
            tyrosine phosphatase type r2a; n=1; Nasonia
            vitripennis|Rep: PREDICTED: similar to receptor tyrosine
            phosphatase type r2a - Nasonia vitripennis
          Length = 2046

 Score =  149 bits (360), Expect = 3e-34
 Identities = 80/206 (38%), Positives = 118/206 (57%), Gaps = 11/206 (5%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            Y   YIATQG LS T   FW M+W+ +  I++M TK  E G+ KC  YWP  ++T   + 
Sbjct: 1844 YRSAYIATQGPLSDTTDDFWRMLWEHNSTIVVMLTKLKEMGREKCHLYWPS-DRTIRYQC 1902

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
            + +    E + P Y LR F VT   + +  RT+  F F  WP+  VP      ++ +  V
Sbjct: 1903 FVVDPIAEYNMPQYILREFKVTDARDGS-SRTVRQFQFIDWPEQGVPKSVDGFIDFIGQV 1961

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
            +   +Q   G D P    + VHCSAG+GRTG FI + ++L++++ EG    +DI +TV++
Sbjct: 1962 HKTKEQF--GQDGP----ITVHCSAGVGRTGVFITLSIVLERMQYEGV---VDIFQTVRI 2012

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFI 570
            +R QR  MVQ E QY+F Y A LE++
Sbjct: 2013 LRTQRPAMVQTEDQYQFCYRASLEYL 2038



 Score =  135 bits (327), Expect = 3e-30
 Identities = 81/202 (40%), Positives = 109/202 (53%), Gaps = 13/202 (6%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            Y+ATQG L  T   FW M W+     I+M TK  ER ++KC++YWP    TE   +  I 
Sbjct: 1560 YVATQGPLQETFADFWRMCWELRSSTIVMMTKLEERTRIKCDQYWP-TRGTETYGQMQIT 1618

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
                     Y +R F V +   +  +R I    FTAWPDH VP  P   L         L
Sbjct: 1619 ISDVQELATYCIRTFQVCRHGYSE-RREIKQLQFTAWPDHGVPEHPAPFLQF-------L 1670

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            +++ T  +P     + VHCSAG+GRTG FIVID +L++I+ E     IDI+  V  +R Q
Sbjct: 1671 RRVRT-LNPTDSGPLIVHCSAGVGRTGCFIVIDSMLERIKHEK---TIDIYGHVTCLRAQ 1726

Query: 549  RSGMVQNEAQYKFIYMAVLEFI 570
            R+ MVQ E QY FI+ A+LE +
Sbjct: 1727 RNYMVQTEDQYIFIHDALLEAV 1748



 Score = 58.4 bits (135), Expect = 5e-07
 Identities = 33/68 (48%), Positives = 43/68 (63%), Gaps = 7/68 (10%)

Query: 202  FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
            F +E+E++   E  Q F     +   N  KNRY N+I +DH+RVIL+ +  DG PGSDYI
Sbjct: 1492 FSQEYESI---EPGQQFTWDHSNMEVNTSKNRYANVIAYDHSRVILQTV--DGIPGSDYI 1546

Query: 262  NANYIRCD 269
            NANY  CD
Sbjct: 1547 NANY--CD 1552



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 9/96 (9%)

Query: 171  TRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIR 230
            T +  R+ H+ +++L +     I  M        EF+ L  +++      +  + P N  
Sbjct: 1753 TEVPARNLHSHIQKLMQPEIDNITGMEL------EFKKLSNIKS-DSTRFISANLPCNKH 1805

Query: 231  KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            KNR  +I+P++ TRV L+  P     GSDYINA+ I
Sbjct: 1806 KNRLVHILPYECTRVCLQ--PQRNIEGSDYINASLI 1839


>UniRef50_Q5BJ20 Cluster: Zgc:113105; n=2; Danio rerio|Rep:
           Zgc:113105 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 513

 Score =  149 bits (360), Expect = 3e-34
 Identities = 81/210 (38%), Positives = 115/210 (54%), Gaps = 14/210 (6%)

Query: 364 VYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK 423
           V N+TYIATQG LS+T+  FW MIWQ +V++IIM  +EIE GK KCE YW   + T  + 
Sbjct: 96  VRNRTYIATQGPLSSTVVDFWRMIWQHNVKVIIMACREIEMGKKKCEVYWASTSDTSTLG 155

Query: 424 KYTILNEFESSTP--DYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
            +T+ +  E S P  +  +R  +V   DE    R + HF +TAWPDH +P  P  +L ++
Sbjct: 156 PFTV-STLEESRPNEEVIVRTLVVNYCDEA---RKVSHFQYTAWPDHGIPDMPDGILGMM 211

Query: 482 LDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
                  Q+    TDP     V +HCSAG GRTG    +D + D +  E    + +I   
Sbjct: 212 ---ELARQKQGNQTDP-----VVIHCSAGCGRTGVICAVDYVNDLLLTEQIQEDFNILDL 263

Query: 542 VQMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
           V  +R QR   VQ + QY F++  V +  +
Sbjct: 264 VLELRRQRPSAVQTKEQYGFVFHTVAQMFQ 293



 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 26/61 (42%), Positives = 38/61 (62%), Gaps = 3/61 (4%)

Query: 207 ETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           +T  + E+  L     G K EN++KNRY++I+P+D TRV L   P      SDYINAN++
Sbjct: 36  KTASLKEDYGLTTNAGGMK-ENVKKNRYRDILPYDQTRVCL--TPTTSEYQSDYINANFV 92

Query: 267 R 267
           +
Sbjct: 93  K 93


>UniRef50_P23467 Cluster: Receptor-type tyrosine-protein phosphatase
            beta precursor; n=74; Chordata|Rep: Receptor-type
            tyrosine-protein phosphatase beta precursor - Homo
            sapiens (Human)
          Length = 1997

 Score =  149 bits (360), Expect = 3e-34
 Identities = 74/212 (34%), Positives = 113/212 (53%), Gaps = 9/212 (4%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            + + YI TQG L  T   FW M+W+++V  I+M T+ +E+G+VKC+ YWP    +     
Sbjct: 1768 FRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGD 1827

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
              +    ES  P++T+R F +  +++    R I HFH+T WPDH VP     ++  +  V
Sbjct: 1828 LILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTV 1887

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
               + +       P      VHCSAG+GRTGTFI +D IL Q+  +     +DI+  V  
Sbjct: 1888 RDYINR------SPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKD---SVDIYGAVHD 1938

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQR 576
            +R  R  MVQ E QY +++  V + +   K R
Sbjct: 1939 LRLHRVHMVQTECQYVYLHQCVRDVLRARKLR 1970



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 25/41 (60%), Positives = 30/41 (73%), Gaps = 2/41 (4%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            PEN  KNRY NI+P+D TRV L ++  D  P SDYINA+YI
Sbjct: 1725 PENRGKNRYNNILPYDATRVKLSNV--DDDPCSDYINASYI 1763


>UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd protein,
            partial; n=5; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to Ptprd protein, partial -
            Strongylocentrotus purpuratus
          Length = 1773

 Score =  148 bits (359), Expect = 4e-34
 Identities = 83/203 (40%), Positives = 119/203 (58%), Gaps = 15/203 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKKYTI 427
            YIATQG L  T+  FW M+W++    I+M TK  ER +VKC++YWP  ++ +    + T+
Sbjct: 1287 YIATQGPLLETMADFWRMVWEQRTNTIVMMTKLEERNRVKCDQYWPTRDQEKYGFIQVTL 1346

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L+  E +T  YT+R F +  K+ +  KR +  F FTAWPDH VP     VL  +  V   
Sbjct: 1347 LDTTELAT--YTVRSFALV-KNRSMEKREVKQFQFTAWPDHGVPEHATSVLAFISRVK-- 1401

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                    +PP    + VHCSAG+GRTG +IVID +L++I+ E     +DI+  V  +R 
Sbjct: 1402 ------SCNPPDAGPIVVHCSAGVGRTGAYIVIDSMLERIKHEK---TVDIYGHVTCLRA 1452

Query: 548  QRSGMVQNEAQYKFIYMAVLEFI 570
            QR+ MVQ E QY FI+ A+ E +
Sbjct: 1453 QRNYMVQTEEQYIFIHEALYEAV 1475



 Score =  148 bits (358), Expect = 5e-34
 Identities = 79/202 (39%), Positives = 118/202 (58%), Gaps = 11/202 (5%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YIATQG L+ T   FW M+W+++  II+M +K  E G+ KC +YWP   ++   + + + 
Sbjct: 1576 YIATQGPLAETTEDFWRMLWEQNSTIIVMLSKLREMGREKCHQYWP-AERSARYQYFVVD 1634

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
               E + P Y LR F VT   +    RTI  F FT WP+  VP      ++ +  V+   
Sbjct: 1635 PMSEYNMPQYILREFKVTDARDGQ-SRTIRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTK 1693

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            +Q   G + P    + VHCSAG+GRTG FI + ++L+++R EG    +D+ +TV+M+R Q
Sbjct: 1694 EQF--GQEGP----ISVHCSAGVGRTGVFITLSVVLERMRYEGI---VDMFQTVKMLRTQ 1744

Query: 549  RSGMVQNEAQYKFIYMAVLEFI 570
            R  MVQ E QY+F Y A LE++
Sbjct: 1745 RPAMVQTEDQYQFCYHAALEYL 1766



 Score = 54.8 bits (126), Expect = 6e-06
 Identities = 31/69 (44%), Positives = 43/69 (62%), Gaps = 9/69 (13%)

Query: 202  FWEEFETLQMMENLQL-FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
            F +E+E+++  +        +E +KP    KNRY N+I +DH+RVIL   P +G PGSDY
Sbjct: 1219 FSQEYESIEPGQQFTWDHSNLETNKP----KNRYANVIAYDHSRVILS--PMEGLPGSDY 1272

Query: 261  INANYIRCD 269
             NANY  CD
Sbjct: 1273 TNANY--CD 1279



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 8/96 (8%)

Query: 171  TRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIR 230
            T +  R+ +  +++L     G  E++    G   EF+ L   +  Q    +  + P N  
Sbjct: 1480 TEVHARNLYGHIQKLTALEPG--ETIT---GMENEFKRLAS-QKAQPSRFVSANIPANKF 1533

Query: 231  KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            KNR  NI P++  RV L+  P  G  GSDYINA++I
Sbjct: 1534 KNRLLNIQPYEGNRVCLQ--PIRGVEGSDYINASHI 1567


>UniRef50_UPI000069DD95 Cluster: Tyrosine-protein phosphatase
           non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell
           protein-tyrosine phosphatase 70Z-PEP) (Lymphoid
           phosphatase) (LyP).; n=1; Xenopus tropicalis|Rep:
           Tyrosine-protein phosphatase non-receptor type 22 (EC
           3.1.3.48) (Hematopoietic cell protein-tyrosine
           phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP). -
           Xenopus tropicalis
          Length = 758

 Score =  148 bits (358), Expect = 5e-34
 Identities = 77/214 (35%), Positives = 111/214 (51%), Gaps = 12/214 (5%)

Query: 365 YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VK 423
           Y + YIATQG L  T+  FW MIW+  + ++++   E E GK KCERYW +L    +   
Sbjct: 97  YPRAYIATQGPLPNTLVDFWRMIWEYKIEVVVIACMEFEMGKKKCERYWVELGSEALQCG 156

Query: 424 KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
            ++I    E    +YT+R   V K       R IY FH+  WPDH VPS    +L+ + D
Sbjct: 157 PFSITCCNEMKKTEYTIR---VLKAAYGKENRIIYQFHYKKWPDHDVPSSVEHILDFIND 213

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
                +QI     PP    +CVHCSAG GRTG    ID I   ++ +       I+  +Q
Sbjct: 214 ----FRQIQKDDSPP----ICVHCSAGCGRTGVICAIDYIWRLLKDKIIPMNFSIYSIIQ 265

Query: 544 MVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
            +R  RS +VQ + QY+ +Y AV+   + E + +
Sbjct: 266 EMRTMRSSLVQTKEQYELVYNAVINLFQNELEMI 299


>UniRef50_A7RS70 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 630

 Score =  147 bits (357), Expect = 6e-34
 Identities = 81/209 (38%), Positives = 116/209 (55%), Gaps = 9/209 (4%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
           +K +IATQG L  T   FW M+W++   +I+M T+ +ERG+VKC RYWP+    +     
Sbjct: 393 HKAFIATQGPLPNTTSDFWRMVWEQGAMVIVMITRCMERGRVKCRRYWPEDGDCDDHVDL 452

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            + +       D+  R F +    +T   RTI HF  T+WPD  VPS     L+IL  V 
Sbjct: 453 RVQHVETQEYEDHVERIFTIDHV-QTGQSRTIIHFQMTSWPDFGVPSSAESCLHILGLVR 511

Query: 486 YRLQQIMTGTDP-----PAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHR 540
                 +    P     P+   + VHCSAGIGRTGTF  +D+ + +++ EG  CE  I  
Sbjct: 512 QAQASAVLAMGPSWKGHPSGPPIVVHCSAGIGRTGTFCTLDINVSRLQHEGV-CE--IVN 568

Query: 541 TVQMVRDQRSGMVQNEAQYKFIYMAVLEF 569
           TV+ +R QR+ M+Q   QY+F ++AVLEF
Sbjct: 569 TVKYLRTQRAHMIQTPEQYEFCHLAVLEF 597



 Score = 36.3 bits (80), Expect = 2.3
 Identities = 18/38 (47%), Positives = 25/38 (65%), Gaps = 2/38 (5%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANY 265
           N+RKNRY +++  + TRV L   P D    SDYI+AN+
Sbjct: 351 NLRKNRYTDVLCVEETRVPLS--PVDEDDCSDYIHANF 386


>UniRef50_Q9Y2R2 Cluster: Tyrosine-protein phosphatase non-receptor
           type 22; n=29; Tetrapoda|Rep: Tyrosine-protein
           phosphatase non-receptor type 22 - Homo sapiens (Human)
          Length = 807

 Score =  147 bits (357), Expect = 6e-34
 Identities = 83/209 (39%), Positives = 112/209 (53%), Gaps = 14/209 (6%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKKY 425
           K YIATQG LSTT+  FW MIW+  V II+M   E E GK KCERYW +  + ++    +
Sbjct: 97  KAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPF 156

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
           ++  E E    DY +R   V    ET   RTIY FH+  WPDH VPS    +L ++ DV 
Sbjct: 157 SVSCEAEKRKSDYIIRTLKVKFNSET---RTIYQFHYKNWPDHDVPSSIDPILELIWDV- 212

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCE-IDIHRTVQM 544
            R  Q            +C+HCSAG GRTG    ID     + K+G   E   +   ++ 
Sbjct: 213 -RCYQ------EDDSVPICIHCSAGCGRTGVICAIDYTW-MLLKDGIIPENFSVFSLIRE 264

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLEFIETE 573
           +R QR  +VQ + QY+ +Y AVLE  + +
Sbjct: 265 MRTQRPSLVQTQEQYELVYNAVLELFKRQ 293



 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 24/43 (55%), Positives = 33/43 (76%), Gaps = 2/43 (4%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           KP+NI+KNRYK+I+P+D++RV L  I  D    S YINAN+I+
Sbjct: 51  KPKNIKKNRYKDILPYDYSRVELSLITSD--EDSSYINANFIK 91


>UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1874

 Score =  147 bits (356), Expect = 8e-34
 Identities = 79/204 (38%), Positives = 117/204 (57%), Gaps = 13/204 (6%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            + YIATQG +  T   FW M+W++    I+M T+E ERG+VKC++YWP  + T+V +   
Sbjct: 1386 RAYIATQGPMQHTAADFWRMVWEQRTFTIVMLTREEERGRVKCDQYWP-TDGTDVYEGIE 1444

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +         +YT+    +  K+  +  R + HF FT WPDH VP+ P   L  L  V +
Sbjct: 1445 VSLVDWVELANYTISTLQIC-KEGASQPREVKHFQFTGWPDHGVPAHPTPFLAFLRRVKF 1503

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
                     +PP    + VHCSAG+GRTG FIVID +L+++R E     +DI+  V ++R
Sbjct: 1504 --------YNPPDAGPIVVHCSAGVGRTGCFIVIDSMLERLRHEE---TVDIYGHVTVLR 1552

Query: 547  DQRSGMVQNEAQYKFIYMAVLEFI 570
             QR+ MVQ + QY F + A+LE +
Sbjct: 1553 TQRNYMVQTQEQYIFSHDAILEAV 1576



 Score =  125 bits (301), Expect = 4e-27
 Identities = 68/202 (33%), Positives = 110/202 (54%), Gaps = 11/202 (5%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            +IATQG L  T+  FW M+ +++  II+M T+  E    KC +YWP  +++   + Y + 
Sbjct: 1676 FIATQGPLQDTVDDFWRMLMEQNSNIIVMLTQLHEGEWEKCYKYWP-TDRSARHQYYIVD 1734

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
               E   P + +R F V      TV R I  FHF  WP+  VP     +++++  V    
Sbjct: 1735 PIAEHEYPQFVIRDFKVKDARSDTV-RNIKQFHFLGWPETGVPKSGEGIIDLIGQVQRAY 1793

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            +Q         +  + VHCS G+GRTG F  + ++L+++R EG    +D+ +TV+++R Q
Sbjct: 1794 EQ------QEEEGPITVHCSDGVGRTGVFTALFIVLERMRSEGV---VDLFQTVKLLRTQ 1844

Query: 549  RSGMVQNEAQYKFIYMAVLEFI 570
            R  MVQ++ QY F Y   LE++
Sbjct: 1845 RPAMVQSQEQYLFCYKTALEYL 1866



 Score = 44.8 bits (101), Expect = 0.007
 Identities = 30/68 (44%), Positives = 38/68 (55%), Gaps = 7/68 (10%)

Query: 202  FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
            F +E+E++   E  Q F         N  KNRY NI  +DH+RV L  I  +G  GSDYI
Sbjct: 1320 FTQEYESI---EPGQTFTADSSQMECNKGKNRYPNIHAYDHSRVRLSYI--NGIEGSDYI 1374

Query: 262  NANYIRCD 269
            NAN+  CD
Sbjct: 1375 NANF--CD 1380



 Score = 39.5 bits (88), Expect = 0.25
 Identities = 20/39 (51%), Positives = 26/39 (66%), Gaps = 2/39 (5%)

Query: 228  NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            N  KNR  NI+P++ TRV +   P  G  GSDYINA++I
Sbjct: 1631 NRPKNRLANILPYETTRVHIS--PVRGVEGSDYINASFI 1667


>UniRef50_Q32NT3 Cluster: MGC52584 protein; n=5; Xenopus|Rep:
           MGC52584 protein - Xenopus laevis (African clawed frog)
          Length = 694

 Score =  147 bits (355), Expect = 1e-33
 Identities = 79/209 (37%), Positives = 118/209 (56%), Gaps = 10/209 (4%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
           YIATQG L  T   FW M+W++ V II+MTT+ IERG++KC +YWP +  ++E    + I
Sbjct: 470 YIATQGPLPKTFDDFWRMVWEQKVLIIVMTTRVIERGRIKCGQYWPLEAGRSEDTGHFII 529

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            N       D+ L    V  K +T   +++ H+ + +WPD  VP     +L+    V   
Sbjct: 530 RNIHIDLFQDFKLTHLEVYNK-QTDESQSVAHYQYMSWPDFGVPKSASAMLDFRTQVKQH 588

Query: 488 ----LQQI-MTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
               +Q + M  T  PA   V VHCSAGIGRTGTF  +D+ L ++   G    +D+ +TV
Sbjct: 589 QAVAVQALGMAWTGHPAGPPVVVHCSAGIGRTGTFCTLDICLSRLEDIG---TVDVLQTV 645

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
           + +R QR+  +Q   QY F YMA++E+ +
Sbjct: 646 KRMRTQRAFSIQTWDQYYFCYMAIIEYAQ 674


>UniRef50_O44329 Cluster: Receptor tyrosine phosphatase; n=1; Hirudo
            medicinalis|Rep: Receptor tyrosine phosphatase - Hirudo
            medicinalis (Medicinal leech)
          Length = 1437

 Score =  147 bits (355), Expect = 1e-33
 Identities = 86/205 (41%), Positives = 120/205 (58%), Gaps = 17/205 (8%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV--K 423
            +  YIATQG L  T   FW M+W++ V  I+M TK  ERG++KC++YWP+   TEV    
Sbjct: 940  SNAYIATQGPLPETFVDFWRMVWEQRVTTIVMMTKLEERGRIKCDQYWPN-RGTEVYGPM 998

Query: 424  KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
              T+++  E +   YTLR F+VTK  +   +  +  F FTAWPDH VP  P      LL 
Sbjct: 999  HVTLVDVVELAI--YTLRTFIVTKTGQQE-RIEVKQFQFTAWPDHGVPEHP----TALLM 1051

Query: 484  VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
             + R++   T    P    + VHCSAG+GRTG FIV+D +L++   E     ID++  V 
Sbjct: 1052 FHRRVRSFHTVDSGP----MVVHCSAGVGRTGRFIVVDRMLERALHEK---TIDVYGHVT 1104

Query: 544  MVRDQRSGMVQNEAQYKFIYMAVLE 568
             +R QR+ MVQ E QY F++ A+LE
Sbjct: 1105 CLRAQRNYMVQTEDQYIFVHDAILE 1129



 Score =  130 bits (313), Expect = 1e-28
 Identities = 75/213 (35%), Positives = 114/213 (53%), Gaps = 18/213 (8%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            Y K YIATQG L++T   FW M+W+ +  I++M  K  E G+ KC +YWP   ++   + 
Sbjct: 1228 YKKAYIATQGPLASTTEDFWRMLWEHNSTIVVMLVKLREMGREKCLQYWPS-ERSARYQY 1286

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
            + +    E + P Y LR F VT   +    RTI  F FT WP+  VP      ++ +  V
Sbjct: 1287 FVVDPMVEYNMPQYILREFKVTDARDGQ-SRTIRQFQFTDWPEQGVPKSGEGFVDFIGQV 1345

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
            +   +Q   G D P    + VHC AG+ RTG FI + ++L+++R EG    +D+ +TV++
Sbjct: 1346 HKTKEQF--GQDGP----ITVHCGAGVSRTGVFIALSVVLERMRYEGV---VDLFQTVRL 1396

Query: 545  VRDQRSGMVQ-------NEAQYKFIYMAVLEFI 570
            +R QR   V+        E  Y F Y A LE++
Sbjct: 1397 LRTQRPCCVKLRLQVQTPEDHYAFCYRAALEYL 1429



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 28/65 (43%), Positives = 41/65 (63%), Gaps = 5/65 (7%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F +E+E++   E  Q F     S   N  KNRY N+I +DH+RV+L+ +  +G  GSDYI
Sbjct: 875 FSQEYESI---EPGQQFTWEASSLDCNKPKNRYANVIAYDHSRVVLQSL--EGISGSDYI 929

Query: 262 NANYI 266
           NAN++
Sbjct: 930 NANFM 934



 Score = 43.2 bits (97), Expect = 0.020
 Identities = 23/43 (53%), Positives = 29/43 (67%), Gaps = 2/43 (4%)

Query: 224  SKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            S P N  KNR  NI+P++ +RV L+ I   G  GSDYINAN+I
Sbjct: 1183 SLPSNKFKNRLVNILPYESSRVTLQLI--RGVDGSDYINANFI 1223


>UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor type,
            sigma isoform 3 variant; n=14; Amniota|Rep: Protein
            tyrosine phosphatase, receptor type, sigma isoform 3
            variant - Homo sapiens (Human)
          Length = 1560

 Score =  147 bits (355), Expect = 1e-33
 Identities = 81/203 (39%), Positives = 123/203 (60%), Gaps = 15/203 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-NKTEVVKKYTI 427
            YIATQG L  T   FW M+W++    I+M T+  E+ ++KC++YWP+   +T    + T+
Sbjct: 1056 YIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTL 1115

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L+  E +T  + +R F +  K+ ++ KR +  F FTAWPDH VP  P   L         
Sbjct: 1116 LDTIELAT--FCVRTFSL-HKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAF------- 1165

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
            L+++ T  +PP    + VHCSAG+GRTG FIVID +L++I+ E     +D++  V ++R 
Sbjct: 1166 LRRVKT-CNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEK---TVDVYGHVTLMRS 1221

Query: 548  QRSGMVQNEAQYKFIYMAVLEFI 570
            QR+ MVQ E QY FI+ A+LE +
Sbjct: 1222 QRNYMVQTEDQYSFIHEALLEAV 1244



 Score =  138 bits (334), Expect = 4e-31
 Identities = 76/202 (37%), Positives = 114/202 (56%), Gaps = 11/202 (5%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG L+ T   FW M+W+ +  I++M TK  E G+ KC +YWP   ++   + + 
Sbjct: 1343 KAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWP-AERSARYQYFV 1401

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +    E + P Y LR F VT   +    RT+  F FT WP+  VP      ++ +  V+ 
Sbjct: 1402 VDPMAEYNMPQYILREFKVTDARDGQ-SRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHK 1460

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
              +Q   G D P    + VHCSAG+GRTG FI + ++L+++R EG    +DI +TV+M+R
Sbjct: 1461 TKEQF--GQDGP----ISVHCSAGVGRTGVFITLSIVLERMRYEGV---VDIFQTVKMLR 1511

Query: 547  DQRSGMVQNEAQYKFIYMAVLE 568
             QR  MVQ E + +  + AV +
Sbjct: 1512 TQRPAMVQTETESRPGWSAVAQ 1533



 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 24/39 (61%), Positives = 30/39 (76%), Gaps = 2/39 (5%)

Query: 228  NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            N  KNRY N+I +DH+RVIL+  P +G  GSDYINANY+
Sbjct: 1011 NKPKNRYANVIAYDHSRVILQ--PIEGIMGSDYINANYV 1047



 Score = 41.5 bits (93), Expect = 0.062
 Identities = 22/41 (53%), Positives = 28/41 (68%), Gaps = 2/41 (4%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            P N  KNR  NI+P++ TRV L+  P  G  GSDYINA++I
Sbjct: 1298 PCNKFKNRLVNIMPYESTRVCLQ--PIRGVEGSDYINASFI 1336


>UniRef50_UPI0000F21332 Cluster: PREDICTED: similar to protein
            tyrosine phosphatase, receptor type, H; n=2; Danio
            rerio|Rep: PREDICTED: similar to protein tyrosine
            phosphatase, receptor type, H - Danio rerio
          Length = 1053

 Score =  146 bits (353), Expect = 2e-33
 Identities = 81/218 (37%), Positives = 125/218 (57%), Gaps = 12/218 (5%)

Query: 357  NGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL 416
            N +P     ++ YIA QG L +T+  FW MIW++    I+M T   E G+VKCE+YWP L
Sbjct: 816  NYMPGYGNASREYIAAQGPLPSTVNDFWRMIWEKKSSTIVMVTNCTEGGRVKCEQYWP-L 874

Query: 417  NKTEVVKKYTILN-EFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPG 475
            + T  + +  ++  + E+ +  +TLR F V K   T+  RT+ HFHFTAWPDH VP    
Sbjct: 875  DYTPCLYENLLVTVKSENKSQSWTLREFNV-KNKMTSETRTVRHFHFTAWPDHGVPRGTE 933

Query: 476  RVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCE 535
             ++     +   ++   + T P       VHCSAG+GRTGT I +D++L Q+ +E     
Sbjct: 934  ELIQFRDLIRQHIESHFS-TGP-----TVVHCSAGVGRTGTLIALDVLLQQLNREK---A 984

Query: 536  IDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETE 573
            + +   VQ +R  R  MVQ E+QY F++  +L+ ++T+
Sbjct: 985  VGVAAFVQEMRLNRPLMVQTESQYVFLHQCILDSLQTK 1022



 Score = 41.1 bits (92), Expect = 0.082
 Identities = 22/41 (53%), Positives = 28/41 (68%), Gaps = 3/41 (7%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           PEN  KNR+ N++P+D +RV L  I   G   SDYINANY+
Sbjct: 781 PENKDKNRFSNVLPYDTSRVHL-TINKAG--DSDYINANYM 818


>UniRef50_UPI0000E816EE Cluster: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 22
           (Hematopoietic cell protein-tyrosine phosphatase
           70Z-PEP) (Lymphoid phosphatase) (LyP); n=1; Gallus
           gallus|Rep: PREDICTED: similar to Tyrosine-protein
           phosphatase non-receptor type 22 (Hematopoietic cell
           protein-tyrosine phosphatase 70Z-PEP) (Lymphoid
           phosphatase) (LyP) - Gallus gallus
          Length = 775

 Score =  146 bits (353), Expect = 2e-33
 Identities = 80/231 (34%), Positives = 119/231 (51%), Gaps = 13/231 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKKY 425
           + YIATQG L TT+  FW MIW+ +V I++M   E E GK KCERYW ++  + +    +
Sbjct: 97  RAYIATQGPLPTTVTDFWRMIWEYEVLIVVMACMEFEMGKKKCERYWAEVGDSALQCGPF 156

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
           +I  E E    +Y +R   V+  +     RTI+ FH+  WPDH +PS    +L ++ +V 
Sbjct: 157 SITCEAEEKKNEYVIRTLKVSLNEAV---RTIHQFHYQNWPDHDIPSSIDPILELIGEV- 212

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
            R  Q      P     +C+HCSAG GRTG    ID     ++         I   +Q +
Sbjct: 213 -RCYQ------PDDSIPICIHCSAGCGRTGVVCAIDYTWKLLKDGIVPVNFSIFSLIQEM 265

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDSPRARSMPVP 596
           R QR  +VQ + QYK +Y AV+E  + + + +    ++A      R  PVP
Sbjct: 266 RTQRPSIVQTKEQYKLVYNAVIELFKRQIEALDAQEDSASSQVLTRH-PVP 315



 Score = 52.4 bits (120), Expect = 3e-05
 Identities = 24/52 (46%), Positives = 36/52 (69%), Gaps = 2/52 (3%)

Query: 216 QLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           +++  +    PENI++NRYK+I+P+DH+RV L  I  D    S YINAN+I+
Sbjct: 42  KIYPTVTAECPENIKRNRYKDILPYDHSRVELSLITSD--TDSHYINANFIK 91


>UniRef50_UPI0000DB6DA7 Cluster: PREDICTED: similar to Protein
           tyrosine phosphatase 99A CG2005-PB, isoform B; n=1; Apis
           mellifera|Rep: PREDICTED: similar to Protein tyrosine
           phosphatase 99A CG2005-PB, isoform B - Apis mellifera
          Length = 1299

 Score =  146 bits (353), Expect = 2e-33
 Identities = 83/219 (37%), Positives = 127/219 (57%), Gaps = 21/219 (9%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-NKTEVVKKY 425
           + YI TQG L  T   FW M+W++ V II+M T  +ERG+ KC+ YWP   ++T    + 
Sbjct: 671 RAYIGTQGPLPPTFDGFWRMVWEQRVSIIVMITNLVERGRKKCDMYWPKKGSETYGCIQV 730

Query: 426 TILNEFESSTPDYTLR----RFLVTKKDETTV---KRTIYHFHFTAWPDHRVPSEPGRVL 478
           T+L E   +T  YT+R    R +  KK +  V   +R I+ +H+T WPDH VP  P  VL
Sbjct: 731 TLLREDVMAT--YTIRTLQIRHMKVKKRKNGVNMGERIIWQYHYTGWPDHGVPEHPLPVL 788

Query: 479 NILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
           + +        +  +  +PP    + VHCSAG+GRTGT+IVID +L Q + +    E+++
Sbjct: 789 SFI--------RKSSNANPPDAGPIVVHCSAGVGRTGTYIVIDAMLKQAKCKN---EVNV 837

Query: 539 HRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
              ++ +R QR+ +VQ E QY FI+ A+ E IE+ +  +
Sbjct: 838 FGFLKHIRTQRNFLVQTEEQYVFIHHALQEAIESGETNI 876



 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 31/68 (45%), Positives = 37/68 (54%), Gaps = 5/68 (7%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPP--GS 258
           GF +E+E +Q       F        EN  KNRY NI+ +DHTRV L      GPP  G 
Sbjct: 600 GFSKEYEFIQSESGK--FTAENSQYVENKAKNRYLNILAYDHTRVQLLSC-GGGPPKKGH 656

Query: 259 DYINANYI 266
           DY+NANYI
Sbjct: 657 DYVNANYI 664



 Score = 39.5 bits (88), Expect = 0.25
 Identities = 21/49 (42%), Positives = 29/49 (59%), Gaps = 2/49 (4%)

Query: 218 FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           F+ +   KP N+ KNR +++I  +  RV L   P  G  GSDYINA +I
Sbjct: 917 FNLVSAIKPCNLHKNRNQDVISIETARVHLT--PKPGIDGSDYINATWI 963



 Score = 35.1 bits (77), Expect = 5.4
 Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 4/53 (7%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK 418
            N+ +I TQ  +  TI  FW M+W  + + ++M T+  E    +   +WP   K
Sbjct: 969  NREFIITQHPMENTIMEFWQMMWDYNAQTVVMLTECDE----EYPEFWPTEGK 1017


>UniRef50_Q5W9G3 Cluster: LAR splice variant 1; n=24; Eutheria|Rep:
            LAR splice variant 1 - Homo sapiens (Human)
          Length = 1484

 Score =  145 bits (352), Expect = 3e-33
 Identities = 79/204 (38%), Positives = 116/204 (56%), Gaps = 11/204 (5%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG L+ +   FW M+W+ +  II+M TK  E G+ KC +YWP   ++   + + 
Sbjct: 1284 KAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWP-AERSARYQYFV 1342

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +    E + P Y LR F VT   +    RTI  F FT WP+  VP      ++ +  V+ 
Sbjct: 1343 VDPMAEYNMPQYILREFKVTDARDGQ-SRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHK 1401

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
              +Q   G D P    + VHCSAG+GRTG FI + ++L+++R EG    +D+ +TV+ +R
Sbjct: 1402 TKEQF--GQDGP----ITVHCSAGVGRTGVFITLSIVLERMRYEGV---VDMFQTVKTLR 1452

Query: 547  DQRSGMVQNEAQYKFIYMAVLEFI 570
             QR  MVQ E QY+  Y A LE++
Sbjct: 1453 TQRPAMVQTEDQYQLCYRAALEYL 1476



 Score =  141 bits (341), Expect = 6e-32
 Identities = 81/201 (40%), Positives = 118/201 (58%), Gaps = 15/201 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-NKTEVVKKYTI 427
            YIATQG L  T+  FW M+W++    ++M T+  E+ +VKC++YWP    +T  + + T+
Sbjct: 997  YIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTL 1056

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L+  E +T  YT+R F +  K  ++ KR +  F F AWPDH VP  P  +L  L  V   
Sbjct: 1057 LDTVELAT--YTVRTFAL-HKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVK-- 1111

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                    +P     + VHCSAG+GRTG FIVID +L++++ E     +DI+  V  +R 
Sbjct: 1112 ------ACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEK---TVDIYGHVTCMRS 1162

Query: 548  QRSGMVQNEAQYKFIYMAVLE 568
            QR+ MVQ E QY FI+ A+LE
Sbjct: 1163 QRNYMVQTEDQYVFIHEALLE 1183



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 32/66 (48%), Positives = 43/66 (65%), Gaps = 7/66 (10%)

Query: 202 FWEEFETLQMMENLQLFD-RMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           F +E+E++   +     +  +E +KP    KNRY N+I +DH+RVIL  I  DG PGSDY
Sbjct: 929 FSQEYESIDPGQQFTWENSNLEVNKP----KNRYANVIAYDHSRVILTSI--DGVPGSDY 982

Query: 261 INANYI 266
           INANYI
Sbjct: 983 INANYI 988



 Score = 39.9 bits (89), Expect = 0.19
 Identities = 21/41 (51%), Positives = 28/41 (68%), Gaps = 2/41 (4%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            P N  KNR  NI+P++ TRV L+  P  G  GSDYINA+++
Sbjct: 1239 PCNKFKNRLVNIMPYELTRVCLQ--PIRGVEGSDYINASFL 1277


>UniRef50_Q05209 Cluster: Tyrosine-protein phosphatase non-receptor
           type 12; n=32; Euteleostomi|Rep: Tyrosine-protein
           phosphatase non-receptor type 12 - Homo sapiens (Human)
          Length = 780

 Score =  145 bits (352), Expect = 3e-33
 Identities = 74/210 (35%), Positives = 115/210 (54%), Gaps = 12/210 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV-KKY 425
           K Y+ATQG L+ T+  FW MIW+ +V II+M  +E E G+ KCERYWP   +  +    +
Sbjct: 101 KAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPF 160

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            I  E E +  DY +R  L+  ++E+   R +Y FH+  WPDH VPS      + +LD+ 
Sbjct: 161 KISCEDEQARTDYFIRTLLLEFQNES---RRLYQFHYVNWPDHDVPSS----FDSILDMI 213

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
             +++     D P    +C+HCSAG GRTG    ID   + ++      E ++   +Q +
Sbjct: 214 SLMRKYQEHEDVP----ICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEM 269

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETEKQ 575
           R QR   VQ + QY+ ++ A+ +  E + Q
Sbjct: 270 RTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 299



 Score = 56.4 bits (130), Expect = 2e-06
 Identities = 26/52 (50%), Positives = 36/52 (69%), Gaps = 2/52 (3%)

Query: 216 QLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           +++    G K EN++KNRYK+I+PFDH+RV L    P     SDYINAN+I+
Sbjct: 46  KIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPS--QDSDYINANFIK 95


>UniRef50_Q6E5N7 Cluster: Receptor protein tyrosine phosphatase psi;
            n=20; Euteleostomi|Rep: Receptor protein tyrosine
            phosphatase psi - Danio rerio (Zebrafish) (Brachydanio
            rerio)
          Length = 1434

 Score =  145 bits (351), Expect = 3e-33
 Identities = 84/220 (38%), Positives = 123/220 (55%), Gaps = 15/220 (6%)

Query: 349  PKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVK 408
            P S     N +   H  N  +IATQG    T+Y FW M+WQE+   I+M TK +E G+VK
Sbjct: 927  PNSDYINANYIDGYHRSNH-FIATQGPKQETVYDFWRMVWQENCFSIVMITKLVEVGRVK 985

Query: 409  CERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDH 468
            C +YWPD ++     K T+L     +  +YT+R F + ++   + K  +  FHFT+WP+H
Sbjct: 986  CCKYWPDESEMYGDIKITLLK--TETLAEYTVRTFALERRG-YSAKHEVCQFHFTSWPEH 1042

Query: 469  RVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIR 528
             VP     +L         ++++ T T   A  VV VHCS G GRTG +IV+D++LD   
Sbjct: 1043 GVPYHATGLLAF-------IRRVKTSTPLDAGPVV-VHCSVGAGRTGCYIVLDVMLDMAE 1094

Query: 529  KEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
             EG    +DI+  V+ +  +R  M+Q E QY FI+ A+LE
Sbjct: 1095 CEGV---VDIYNCVKTLCSRRINMIQTEEQYIFIHDAILE 1131



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 51/209 (24%), Positives = 95/209 (45%), Gaps = 20/209 (9%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKV-KCERYWPDLNKTEVVKKYTI 427
            +I T   L  T   FW +++      ++M  +  +      C +YWP+      +++Y  
Sbjct: 1235 FIVTPHPLPGTTSDFWRLVFDYGCTSVVMLNQLNQSNSAWPCVQYWPEPG----LQQYGP 1290

Query: 428  LN-EFESSTPDYTLRRFLVTKKDETTVKR---TIYHFHFTAWPDHR-VPSEPGRVLNILL 482
            +  EF S + D  +   L   K+ T ++     +  F F  W  +R VP      LN+L 
Sbjct: 1291 MQVEFLSMSADEDIITRLFRVKNVTRLQEGQLVVCQFQFLRWSAYRDVPDSKKAFLNLLA 1350

Query: 483  DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
             V    ++   G          VHC  G GR+GT+   +++++ I+ +     +D+   V
Sbjct: 1351 SVQKWQRECGEGR-------TVVHCLNGGGRSGTYCASNILMEMIQYQNI---VDVFYAV 1400

Query: 543  QMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
            + +R+ +  MV+   QY+F Y  VLE+++
Sbjct: 1401 KTLRNAKPNMVETLEQYRFCYELVLEYLD 1429



 Score = 38.3 bits (85), Expect = 0.58
 Identities = 21/49 (42%), Positives = 29/49 (59%), Gaps = 2/49 (4%)

Query: 218 FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           FD  + +K ++  K R+  ++ +D  RV L   P  G P SDYINANYI
Sbjct: 891 FDGWDINKKKDKTKGRHDTLMGYDRHRVKLH--PLLGDPNSDYINANYI 937


>UniRef50_Q5C521 Cluster: SJCHGC03800 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC03800 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 241

 Score =  145 bits (351), Expect = 3e-33
 Identities = 64/122 (52%), Positives = 86/122 (70%), Gaps = 6/122 (4%)

Query: 456 TIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTG 515
           T+YH+HFT WPDH  PS+P  VL+ + D++ R   I      P    + VHCSAGIGRTG
Sbjct: 74  TVYHYHFTVWPDHGTPSDPSCVLDFMHDISARHDSI------PGSGPIVVHCSAGIGRTG 127

Query: 516 TFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQ 575
            FIVIDM+++ I+  G +C+IDI RT+Q VR+QRSGMVQ E QY+FIY AV +++ T  +
Sbjct: 128 AFIVIDMLINYIKTMGLNCDIDISRTIQAVREQRSGMVQTETQYRFIYKAVQQYVNTMSK 187

Query: 576 RV 577
           R+
Sbjct: 188 RI 189


>UniRef50_P06800 Cluster: Leukocyte common antigen precursor; n=13;
           Eutheria|Rep: Leukocyte common antigen precursor - Mus
           musculus (Mouse)
          Length = 1291

 Score =  145 bits (351), Expect = 3e-33
 Identities = 77/214 (35%), Positives = 116/214 (54%), Gaps = 12/214 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK-TEVVKKY 425
           + YIA QG    T+  FW MIW++   +I+M T+  E  + KC  YWP + + T   K  
Sbjct: 707 RKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFKDI 766

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            +        PDY +++  V  K E    R + H  FT+WPDH VP +P    ++LL + 
Sbjct: 767 VVTINDHKRCPDYIIQKLNVAHKKEKATGREVTHIQFTSWPDHGVPEDP----HLLLKLR 822

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
            R+         P    + VHCSAG+GRTGT+I ID +L+ +  EG   ++D++  V  +
Sbjct: 823 RRVNAFSNFFSGP----IVVHCSAGVGRTGTYIGIDAMLEGLEAEG---KVDVYGYVVKL 875

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGL 579
           R QR  MVQ EAQY  I+ A++E+ +  + +V L
Sbjct: 876 RRQRCLMVQVEAQYILIHQALVEYNQFGETQVNL 909



 Score = 98.3 bits (234), Expect = 5e-19
 Identities = 58/209 (27%), Positives = 104/209 (49%), Gaps = 7/209 (3%)

Query: 370  IATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILN 429
            IA QG L  TI  FW MI+Q  V++I+M T+ +   +  C +YW +  +T    +  + +
Sbjct: 1020 IAAQGPLKETIGDFWQMIFQRKVKVIVMLTELVNGDQEVCAQYWGEGKQTYGDMEVEMKD 1079

Query: 430  EFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQ 489
               +S   YTLR F + +  +    RT+Y +  T W    +P+EP  +++++ D+  +L 
Sbjct: 1080 TNRASA--YTLRTFEL-RHSKRKEPRTVYQYQCTTWKGEELPAEPKDLVSMIQDLKQKLP 1136

Query: 490  QIM-TGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            +    G      A + VHC  G  +TG F  +  +L+    E     +D+ + V+ +R  
Sbjct: 1137 KASPEGMKYHKHASILVHCRDGSQQTGLFCALFNLLESAETEDV---VDVFQVVKSLRKA 1193

Query: 549  RSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
            R G+V +  QY+F+Y  +      +  +V
Sbjct: 1194 RPGVVCSYEQYQFLYDIIASIYPAQNGQV 1222



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 4/65 (6%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F  EF+++  +     F   +  KP N  KNRY +I+P+D+ RV L +I  +G  GS YI
Sbjct: 640 FLAEFQSIPRV--FSKFPIKDARKPHNQNKNRYVDILPYDYNRVELSEI--NGDAGSTYI 695

Query: 262 NANYI 266
           NA+YI
Sbjct: 696 NASYI 700


>UniRef50_Q17N21 Cluster: Protein-tyrosine phosphatase; n=1; Aedes
            aegypti|Rep: Protein-tyrosine phosphatase - Aedes aegypti
            (Yellowfever mosquito)
          Length = 1080

 Score =  144 bits (350), Expect = 4e-33
 Identities = 80/229 (34%), Positives = 125/229 (54%), Gaps = 15/229 (6%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            Y + YIATQG    T + FW MI Q +V  I+M T+ +E  ++KC +Y+P  N+T   + 
Sbjct: 823  YQREYIATQGPKKETCFDFWRMILQYEVETIVMLTQTVENDRIKCYQYFPRFNQTLRFRD 882

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
              +    E +   Y  R FLV++ + T   R ++H+HF AWPDH  P+    ++  +   
Sbjct: 883  VAVKCTQELNLSFYQKRLFLVSRDNLT---RPVFHYHFLAWPDHGCPASASDLIKFI--- 936

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
                 +I+          V VHCSAG+GRTGT I +D+IL +I++E    +I+I+ TV+ 
Sbjct: 937  -----KIIRSERKNLALPVVVHCSAGVGRTGTLIALDIILQRIQQEK---KINIYETVKQ 988

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEF-IETEKQRVGLGPEAAQDSPRARS 592
            +R QR  MVQ   QY F+Y A LE+     +++     E +  S R+ +
Sbjct: 989  LRSQRVKMVQTSEQYAFLYHACLEYTTRNNRKKPKTSDEESASSTRSNT 1037



 Score = 35.1 bits (77), Expect = 5.4
 Identities = 21/44 (47%), Positives = 27/44 (61%), Gaps = 4/44 (9%)

Query: 227 ENIRKNRYKNIIPFDHTRVILK--DI--PPDGPPGSDYINANYI 266
           EN RKNRY  I P+D  RV L+  DI    +    +DYINA++I
Sbjct: 775 ENERKNRYLGIFPYDGNRVPLECDDIVTEEEDEEVNDYINASFI 818


>UniRef50_A5D6T3 Cluster: Si:dkey-78k11.1 protein; n=3; Danio
           rerio|Rep: Si:dkey-78k11.1 protein - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 887

 Score =  144 bits (348), Expect = 8e-33
 Identities = 73/202 (36%), Positives = 112/202 (55%), Gaps = 12/202 (5%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKK 424
           +K YIATQG LS T+  FW MIW+ ++++I+M  +E E G+ KCERYWP+      V + 
Sbjct: 101 SKAYIATQGPLSNTVLDFWRMIWEYNIQVIVMVCREFEMGRKKCERYWPESKGDVFVCEA 160

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
           +TIL E + +  DY  R   VT K E+   R +   H+  WPDH VP     +L +L ++
Sbjct: 161 FTILYESDENKGDYLTRTLKVTFKQES---RRLKQLHYVNWPDHGVPDSIPAILELLQEM 217

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
             R+ Q         +  +C+HCSAG GRTG    ID   + ++++    +  I   V+ 
Sbjct: 218 --RIYQ------DNEEIPICIHCSAGCGRTGALCAIDYTWNLLKRQIIPEDFSIFELVKG 269

Query: 545 VRDQRSGMVQNEAQYKFIYMAV 566
           +R QR  +VQ + QY+ +Y  +
Sbjct: 270 MRTQRPSVVQTKEQYELVYRTI 291



 Score = 48.0 bits (109), Expect = 7e-04
 Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 6/78 (7%)

Query: 194 ESMAYKQGFWEEFETLQMMENLQLFDRM----EGSKPENIRKNRYKNIIPFDHTRVILKD 249
           E    + GF  EF  L+        +R        K +N++KNRYK+I+PFDH+RV L  
Sbjct: 21  EDETAENGFAGEFLKLKRQSTKYRAERTYPTTAADKQDNVKKNRYKDIVPFDHSRVKLSL 80

Query: 250 IPPDGPPGSDYINANYIR 267
                   +DYINA++I+
Sbjct: 81  FTSKN--DTDYINASFIK 96


>UniRef50_A4QN87 Cluster: LOC569591 protein; n=3; Danio rerio|Rep:
           LOC569591 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 299

 Score =  143 bits (347), Expect = 1e-32
 Identities = 76/200 (38%), Positives = 113/200 (56%), Gaps = 14/200 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKT-EVVKKYTI 427
           YIA QG L TT+  FW M+W++   +I M T+E+E GKVKC+RYWPD  ++ ++V     
Sbjct: 99  YIACQGPLPTTLGDFWQMVWEQKSNVIAMMTQEVEGGKVKCQRYWPDTPRSPQMVDDRLQ 158

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
           +   +    D  + R +  K  +T   + + H ++T WPDH  P++P ++L     ++Y 
Sbjct: 159 VTLVKDQHLDNFVIRLIELKDVQTNELQRVTHLNYTGWPDHGTPTQPEQLLTF---ISYM 215

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
               ++G        +  HCSAGIGR+GT I ID++L  I K   D + DI   V+ +R 
Sbjct: 216 RHIHLSGP-------IITHCSAGIGRSGTLICIDVVLGLISK---DADFDISDIVRTMRL 265

Query: 548 QRSGMVQNEAQYKFIYMAVL 567
           QR GMVQ E QY F Y  +L
Sbjct: 266 QRQGMVQTEEQYIFCYQVIL 285



 Score = 52.4 bits (120), Expect = 3e-05
 Identities = 31/64 (48%), Positives = 41/64 (64%), Gaps = 9/64 (14%)

Query: 204 EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
           +EFE LQ +  L   + + G   EN +KNRYKNI+PFD TRV+L +   DG     YINA
Sbjct: 35  QEFENLQNLRPLD--ECLIGQTKENKKKNRYKNIVPFDTTRVLLGN---DG----GYINA 85

Query: 264 NYIR 267
           N+I+
Sbjct: 86  NFIK 89


>UniRef50_UPI00015B5CF6 Cluster: PREDICTED: similar to Si:dkey-21k10.1
            protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar
            to Si:dkey-21k10.1 protein - Nasonia vitripennis
          Length = 1992

 Score =  143 bits (346), Expect = 1e-32
 Identities = 87/209 (41%), Positives = 113/209 (54%), Gaps = 14/209 (6%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG    TI  FW MIWQE+V+II M    +E    KCE+YWP     +++   T
Sbjct: 1501 KAYIATQGPKPNTIVDFWRMIWQENVQIICMMANLVEND--KCEQYWPSAVGKKILYG-T 1557

Query: 427  ILNEFESST--PDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
            IL +F S     DYT R F V     T   RTI H H+TAWPDH VPS P  ++  L   
Sbjct: 1558 ILVQFSSEEIHSDYTYRTFKV--YCGTLEARTIEHLHYTAWPDHGVPSSPRSIVAFL--- 1612

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
              +LQ+     D   Q  + VHCSAG+GRTGT IV+D+ L Q   E     I +   +  
Sbjct: 1613 -QQLQRHAPFDDRANQPPIVVHCSAGVGRTGTLIVLDICLHQAFCEKV---IYVFENLLS 1668

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFIETE 573
            VR  R  MV N  QY  +++ ++E+  T+
Sbjct: 1669 VRQGRLNMVDNTEQYLLVHLVLVEYFHTK 1697



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 22/44 (50%), Positives = 30/44 (68%), Gaps = 2/44 (4%)

Query: 223  GSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            GS+ E   KNRY N+ P+D +RV+L  +  +  P SDYINAN+I
Sbjct: 1452 GSQSETKPKNRYANLFPYDESRVVLDKLSEE--PFSDYINANFI 1493



 Score = 41.1 bits (92), Expect = 0.082
 Identities = 41/202 (20%), Positives = 82/202 (40%), Gaps = 17/202 (8%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YI TQ  + TT+  FW M+ + +V  ++       +    CE    D  +    K   I+
Sbjct: 1794 YITTQLPMPTTLADFWRMLSELNVEYVLALQLPDLQDPTYCELI-ADSQEFGSTKYLKII 1852

Query: 429  NEFESSTPD---YTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
             + +SST D   Y     L+    E + ++ +    +  WP+  +P  P + L       
Sbjct: 1853 RQ-QSSTTDSKYYLKEEVLIIDSSEPSKEQRVKILSYKNWPEFSLP--PVKEL------- 1902

Query: 486  YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
             +L +         +  + + C+ G+  +G ++    +L   ++   D E D+ + VQ +
Sbjct: 1903 VQLWKAFDELPKTNKCPIVIACANGVTASGIWLASSFLL---KRMTVDKECDVPQAVQAI 1959

Query: 546  RDQRSGMVQNEAQYKFIYMAVL 567
            R  R   +      +++Y   L
Sbjct: 1960 RRCRKDFLSQPKYLEYLYDVAL 1981


>UniRef50_UPI00015B5B23 Cluster: PREDICTED: similar to
            protein-tyrosine phosphatase; n=1; Nasonia
            vitripennis|Rep: PREDICTED: similar to protein-tyrosine
            phosphatase - Nasonia vitripennis
          Length = 1306

 Score =  142 bits (345), Expect = 2e-32
 Identities = 80/206 (38%), Positives = 116/206 (56%), Gaps = 14/206 (6%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
            N+ YIA QG    T Y FW MI Q DV++I+M T+ +E+GK KC +Y+P + +T   +K 
Sbjct: 953  NEEYIACQGPKEDTTYDFWRMIDQYDVKMILMLTQLVEKGKEKCHQYYPTIRETFNYEKL 1012

Query: 426  TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            +I    E    ++T +R LV +KD+   +RTI H HF  WPDH VP +         D  
Sbjct: 1013 SIRCTSELDYRNFT-QRTLVLQKDDK--RRTITHLHFKDWPDHDVPDD--------FDAM 1061

Query: 486  YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
                QI        + +  +HCSAGIGRTGT I ID++L  IR    + ++D+  TV  +
Sbjct: 1062 IHFCQIFRKQFSTVKGLAVIHCSAGIGRTGTLIAIDILLQSIRD---NRKLDVFGTVYRL 1118

Query: 546  RDQRSGMVQNEAQYKFIYMAVLEFIE 571
            R  R  MVQ E+QY +IY  + + ++
Sbjct: 1119 RRHRLNMVQRESQYAYIYNCIRQVLK 1144



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 27/64 (42%), Positives = 40/64 (62%), Gaps = 4/64 (6%)

Query: 205 EFETLQMME-NLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
           EF+ LQ +  +LQ+          N +KNRY +I+P+D +RV L+ I  D  P +DYINA
Sbjct: 888 EFQLLQTLSVDLQMPSNA-ACLQANRKKNRYSDILPYDFSRVKLEVI--DNDPNTDYINA 944

Query: 264 NYIR 267
           ++IR
Sbjct: 945 SFIR 948


>UniRef50_UPI000065E288 Cluster: Receptor-type tyrosine-protein
            phosphatase U precursor (EC 3.1.3.48) (R-PTP-U)
            (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic
            carcinoma phosphatase 2) (PCP-2).; n=1; Takifugu
            rubripes|Rep: Receptor-type tyrosine-protein phosphatase
            U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine
            phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase
            2) (PCP-2). - Takifugu rubripes
          Length = 1341

 Score =  142 bits (344), Expect = 2e-32
 Identities = 79/200 (39%), Positives = 114/200 (57%), Gaps = 14/200 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            +IATQG     IY FW M+WQE+   I+M TK +E G++KC +YWPD  +     K T+L
Sbjct: 853  FIATQGPKQEMIYDFWRMVWQENCFSIVMITKLVEVGRMKCCKYWPDDTELYGDIKITLL 912

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
                 +  +YT+R F + ++     K  +  FHFT+WP+H VP     +L         L
Sbjct: 913  K--TETLAEYTVRTFAMERRG-YPAKHEVCQFHFTSWPEHGVPYHATGLLAF-------L 962

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            +++   T P A  VV VHCS G GRTG +IV+D++LD    EG    +DI+  V+ +  +
Sbjct: 963  RRVKASTPPDAGPVV-VHCSMGAGRTGCYIVLDVMLDMAECEGV---VDIYNCVKTLCSR 1018

Query: 549  RSGMVQNEAQYKFIYMAVLE 568
            R  M+Q E QY FI+ A+LE
Sbjct: 1019 RINMIQTEEQYVFIHDAILE 1038



 Score = 63.7 bits (148), Expect = 1e-08
 Identities = 52/208 (25%), Positives = 88/208 (42%), Gaps = 18/208 (8%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKV-KCERYWPDLNKTEVVKKYTI 427
            ++ T   L  T   FW +++      ++M  +  +      C +YWP+    +     T+
Sbjct: 1142 FVVTPHPLPGTTTDFWRLVYDYGCTSVVMLNQLNQSNSAWPCLQYWPEPGLQQF-GPMTV 1200

Query: 428  LNEFESSTPDYTLRRFLV---TKKDETTVKRTIYHFHFTAWPDHR-VPSEPGRVLNILLD 483
                 ++  D  +R F V   T+  E  +   + HF F  W  +R VP      L++L  
Sbjct: 1201 ELLSRTADDDVIIRLFRVQNITRLQEGQL--VVRHFQFLRWSPYRDVPDSKKAFLSLLAQ 1258

Query: 484  VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
            V+   ++   G          VHC  G GR+GTF    MIL+ IR        D+    +
Sbjct: 1259 VHNWQRECGEGR-------TVVHCLNGGGRSGTFCACTMILEMIRHHSV---ADVFFAAK 1308

Query: 544  MVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
             +R+ +  MV+   QY+F Y    E++E
Sbjct: 1309 TLRNAKPNMVETMEQYRFCYDLAQEYLE 1336



 Score = 37.5 bits (83), Expect = 1.0
 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%)

Query: 218 FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           FD  + SK ++  K R+ +++  D  RV L  +  D  P SDY+NANYI
Sbjct: 798 FDGWDVSKKKDKTKGRHDSLLSHDRHRVKLHSLLAD--PCSDYVNANYI 844


>UniRef50_Q91054 Cluster: CD45 homolog; n=1; Heterodontus
           francisci|Rep: CD45 homolog - Heterodontus francisci
           (Horn shark)
          Length = 1200

 Score =  142 bits (343), Expect = 3e-32
 Identities = 73/205 (35%), Positives = 114/205 (55%), Gaps = 12/205 (5%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK-TEVVKK 424
           ++ YIA QG    T   FW M+W++   II+M T+  E  + KC +YWP ++  ++    
Sbjct: 617 SRKYIAAQGPKEETSDDFWKMVWEQKATIIVMVTRCEEGKRPKCAQYWPTMDSPSKTFGD 676

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
            T+    E   PDY +R+  ++ K E T +R + H  F  WPDH VP +P  +L +   V
Sbjct: 677 LTVRISEEQWCPDYVIRKLFISHKSEKTPEREVTHIQFIRWPDHGVPEDPHLLLKLRQRV 736

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
           N   + + +G        + VHCSAG+GRTG++I ID ++  +  EG    +D++  +  
Sbjct: 737 N-AFRNLFSGP-------IVVHCSAGVGRTGSYIGIDAMMQGLEAEG---RVDVYGYIVQ 785

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLEF 569
           +R QR  MVQ EAQY  I+ A+LE+
Sbjct: 786 LRRQRCLMVQVEAQYILIHQALLEY 810



 Score =  102 bits (245), Expect = 2e-20
 Identities = 64/201 (31%), Positives = 106/201 (52%), Gaps = 13/201 (6%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            +++T IATQ  L  TI  FW M++Q   RII M  K ++  K  C +YW D  KT     
Sbjct: 927  HSETLIATQTPLPETIADFWMMVYQRKARIIAMLGK-LKDDK-DCSQYWEDDKKT-YDDI 983

Query: 425  YTILNEFESSTPDYTLRRFLV--TKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
              +L+E  +  P++ +R F +  TK+ ET   R +Y +HF  W +  +P +P     ++ 
Sbjct: 984  EVVLSEC-NKQPEFIVRIFEIRHTKRKET---RQVYQYHFHDWAESELPEDPSNFTKMIR 1039

Query: 483  DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
             +  +L  +       + +++ VHCS G  +TG F  + ++LD    E     ID+ +TV
Sbjct: 1040 SIKEKLSTLQEPESSLSPSLI-VHCSDGAKKTGVFYALWILLDNADTENV---IDVLQTV 1095

Query: 543  QMVRDQRSGMVQNEAQYKFIY 563
            +++R  R G+V    QY+F+Y
Sbjct: 1096 KVLRKARPGLVSTFEQYQFLY 1116



 Score = 48.8 bits (111), Expect = 4e-04
 Identities = 32/91 (35%), Positives = 47/91 (51%), Gaps = 10/91 (10%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F  EF+++  +     F   E  +  N  KNRY +I+P+DH RV L   P  G  GSDYI
Sbjct: 551 FLAEFQSIPRV--FSKFSVKEARRGCNTNKNRYVDILPYDHNRVQLS--PIAGEQGSDYI 606

Query: 262 NANYIRCDSMDSISDSQEF-TGNGSTENGKD 291
           NA++I     D  ++S+++    G  E   D
Sbjct: 607 NASFI-----DGFNESRKYIAAQGPKEETSD 632


>UniRef50_Q4RK94 Cluster: Chromosome 18 SCAF15030, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 18
           SCAF15030, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 729

 Score =  142 bits (343), Expect = 3e-32
 Identities = 78/209 (37%), Positives = 115/209 (55%), Gaps = 10/209 (4%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
           Y+ATQG L  T   FW M+W++ V II+MTT+ +ERG+VKC +YWP +  +TE    + I
Sbjct: 518 YVATQGPLPKTFADFWRMVWEQMVLIIVMTTRVVERGRVKCGQYWPLEEGRTEQHGYFRI 577

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            N       D+ L   L     ++  +R + H+ + +WPD  VP     +L+    V  R
Sbjct: 578 RNAHIQVFQDFKLSH-LELYNTQSGERREVCHYLYLSWPDFGVPKSASAMLDFREHVLQR 636

Query: 488 LQQIM-----TGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
            +  +     + T PP    V VHCSAGIGRTGTF  +D+ L ++   G    +DI  TV
Sbjct: 637 RETAVQSLGSSWTGPPGGPPVVVHCSAGIGRTGTFCTLDICLSRLEDIG---TVDIRETV 693

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
           + +R QR+  +Q   QY F Y AV+E+ +
Sbjct: 694 RRMRTQRAFSIQTWDQYYFCYTAVIEYAQ 722



 Score = 40.3 bits (90), Expect = 0.14
 Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 3/68 (4%)

Query: 199 KQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGS 258
           K+G ++E+E ++       FD  +  K  N  KNRY +++  DH+RV L  +  D    S
Sbjct: 445 KKGIYQEYEDIRKEPPAGTFDYSK--KLSNQIKNRYSDVLCLDHSRVQLCKLDGDDET-S 501

Query: 259 DYINANYI 266
           DYIN +++
Sbjct: 502 DYINGSFM 509


>UniRef50_A7SDC7 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
           Predicted protein - Nematostella vectensis
          Length = 296

 Score =  142 bits (343), Expect = 3e-32
 Identities = 81/211 (38%), Positives = 121/211 (57%), Gaps = 17/211 (8%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK---KY 425
           YIATQG L  T   FW MIW++ V ++ M T + E GKVKC RYWPD N  + +K   ++
Sbjct: 100 YIATQGPLPNTTKDFWQMIWEQGVEVVAMVTLDKEGGKVKCHRYWPD-NTNQPLKLGGRF 158

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            + +  + +  D  ++R +  K  ++     I H +F  WPDH VP  P  ++     V 
Sbjct: 159 EV-SLLKQTNYDSFVQRDIAVKHLQSGKSIEIAHLNFVKWPDHGVPRSPVEMVQF---VA 214

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
           Y ++ + T     +QA V VHCSAGIGRTG  I +D+ L  + +   D   DI++T++ +
Sbjct: 215 Y-MRSLAT-----SQAPVVVHCSAGIGRTGALIAVDVALGLMER---DKPFDINQTIRDL 265

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETEKQR 576
           R+QR GM+Q + QY F Y A LE +++  QR
Sbjct: 266 REQRQGMIQTKDQYIFCYKACLEVLKSLAQR 296



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 27/64 (42%), Positives = 37/64 (57%), Gaps = 7/64 (10%)

Query: 204 EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
           EEF+ L+ ++     D   G    N  KNRY+N++P++ TRV L      G  G DYINA
Sbjct: 34  EEFKDLREIKPTDGCD--SGKNQANTDKNRYRNVLPYEATRVRL-----SGSSGEDYINA 86

Query: 264 NYIR 267
           N+IR
Sbjct: 87  NHIR 90


>UniRef50_P34138 Cluster: Tyrosine-protein phosphatase 2; n=2;
           Dictyostelium discoideum|Rep: Tyrosine-protein
           phosphatase 2 - Dictyostelium discoideum (Slime mold)
          Length = 377

 Score =  142 bits (343), Expect = 3e-32
 Identities = 80/225 (35%), Positives = 121/225 (53%), Gaps = 20/225 (8%)

Query: 364 VYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK 423
           + N TYI TQG L  TI  FW MIW+++  II+M T+E E  K KC++YWPD ++ E   
Sbjct: 149 INNGTYICTQGPLLNTIVDFWKMIWEQNSNIIVMLTREEENFKTKCDKYWPDKDE-ERYG 207

Query: 424 KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
            + +  +   + PD  +RR    +  +    R IYHF +T WPDH  P      L  +  
Sbjct: 208 NFIVKFDNNITIPDILIRREFTLENLKDNKTRKIYHFQYTTWPDHGTPVSTTGFLKFVSF 267

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCE----IDIH 539
           V++  +             + VHCSAGIGR+GTF+ I  I+ +  K   + +    I++ 
Sbjct: 268 VDHEKR----------SGPIVVHCSAGIGRSGTFVAIHSIVAKFAKHYDEKKQAPSINLP 317

Query: 540 RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIET-----EKQRVGL 579
           + V  +R++R GMVQ   QY+F Y+A+ E + T     +K+R GL
Sbjct: 318 KLVVEMRNERPGMVQTRDQYRFCYLAISEAMNTVLKKEQKKRKGL 362


>UniRef50_A7RL98 Cluster: Predicted protein; n=4; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 272

 Score =  141 bits (342), Expect = 4e-32
 Identities = 71/211 (33%), Positives = 117/211 (55%), Gaps = 9/211 (4%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           KTYIA QG L ++   FW M+WQE   +I+M T  IER ++KC +YWP  ++       T
Sbjct: 59  KTYIAAQGPLESSCNDFWQMVWQEKCSVIVMLTGLIERNELKCHQYWPSTDQPAAYGVLT 118

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           +  + +    DYT+R  L++K+      R I+ + FT+WP   VP +   +L    ++  
Sbjct: 119 VSLKKKEEFSDYTVRSLLLSKQGTLKEVRLIHQYQFTSWPHRGVPQQTAALLRFRKNIIN 178

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
           R   + + + P       +HCSAG+GRTG F+VID +L Q +++     +DI+  V  + 
Sbjct: 179 RSPHV-SESGP-----WIIHCSAGVGRTGIFLVIDAMLRQAKEKKV---VDIYNYVHSIE 229

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
           + R  ++Q + QY FI+  +LE +  E +R+
Sbjct: 230 EDRPYIIQTKDQYVFIHQTILEALIAENKRI 260



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 20/40 (50%), Positives = 25/40 (62%), Gaps = 4/40 (10%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           N  KNRY NI  +DH+RV+L+        G DYINA YI+
Sbjct: 17  NRAKNRYGNIQAYDHSRVMLR----GAGSGCDYINATYIK 52


>UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar precursor;
            n=37; cellular organisms|Rep: Tyrosine-protein
            phosphatase Lar precursor - Drosophila melanogaster
            (Fruit fly)
          Length = 2029

 Score =  141 bits (341), Expect = 6e-32
 Identities = 75/207 (36%), Positives = 117/207 (56%), Gaps = 13/207 (6%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            Y   YIA QG +      FW M+W+ +  I++M TK  E G+ KC +YWP  ++  V  +
Sbjct: 1827 YRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWP--HERSVRYQ 1884

Query: 425  YTILNEF-ESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
            Y +++   E + P Y LR F VT   + +  RT+  F F  WP+  VP      ++ +  
Sbjct: 1885 YYVVDPIAEYNMPQYKLREFKVTDARDGS-SRTVRQFQFIDWPEQGVPKSGEGFIDFIGQ 1943

Query: 484  VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
            V+   +Q   G D P    + VHCSAG+GR+G FI + ++L++++ EG    +D+ +TV+
Sbjct: 1944 VHKTKEQF--GQDGP----ITVHCSAGVGRSGVFITLSIVLERMQYEGV---LDVFQTVR 1994

Query: 544  MVRDQRSGMVQNEAQYKFIYMAVLEFI 570
            ++R QR  MVQ E QY F Y A LE++
Sbjct: 1995 ILRSQRPAMVQTEDQYHFCYRAALEYL 2021



 Score =  138 bits (335), Expect = 3e-31
 Identities = 79/205 (38%), Positives = 112/205 (54%), Gaps = 13/205 (6%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
            +  Y+ATQG L  T   FW M W+     I+M T+  ER ++KC++YWP        + +
Sbjct: 1539 HNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIF 1598

Query: 426  TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
              + E +     Y++R F + ++     +R I    FTAWPDH VP  P   L  L    
Sbjct: 1599 VTITETQ-ELATYSIRTFQLCRQGFND-RREIKQLQFTAWPDHGVPDHPAPFLQFL---- 1652

Query: 486  YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
             R  + +T   PP    V VHCSAG+GRTG +IVID +L++++ E     IDI+  V  +
Sbjct: 1653 -RRCRALT---PPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKI---IDIYGHVTCL 1705

Query: 546  RDQRSGMVQNEAQYKFIYMAVLEFI 570
            R QR+ MVQ E QY FI+ A+LE I
Sbjct: 1706 RAQRNYMVQTEDQYIFIHDAILEAI 1730



 Score = 48.4 bits (110), Expect = 5e-04
 Identities = 30/70 (42%), Positives = 40/70 (57%), Gaps = 7/70 (10%)

Query: 200  QGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSD 259
            Q F +E+E++   E  Q F     +   N  KNRY N+  +DH+RV L  +  +G  GSD
Sbjct: 1472 QKFSQEYESI---EPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAV--EGVVGSD 1526

Query: 260  YINANYIRCD 269
            YINANY  CD
Sbjct: 1527 YINANY--CD 1534



 Score = 42.3 bits (95), Expect = 0.035
 Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 8/96 (8%)

Query: 171  TRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIR 230
            T +  R+ HT +++L     G   S     G   EF+ L  ++ +     +  + P N  
Sbjct: 1735 TEVPARNLHTHLQKLLITEPGETIS-----GMEVEFKKLSNVK-MDSSKFVTANLPCNKH 1788

Query: 231  KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            KNR  +I+P++ +RV L   P  G  GSDY+NA++I
Sbjct: 1789 KNRLVHILPYESSRVYL--TPIHGIEGSDYVNASFI 1822


>UniRef50_Q15426 Cluster: Protein-tyrosine phosphatase receptor type H
            precursor; n=19; Eutheria|Rep: Protein-tyrosine
            phosphatase receptor type H precursor - Homo sapiens
            (Human)
          Length = 1117

 Score =  140 bits (339), Expect = 1e-31
 Identities = 74/207 (35%), Positives = 113/207 (54%), Gaps = 10/207 (4%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            +IATQG L  T+  FW ++W++    ++M T  +E G+VKCE YWP  ++        + 
Sbjct: 891  FIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPLDSQPCTHGHLRVT 950

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
               E    ++T+R  L+ + +E     ++  FH+ AWPDH VPS P  +L     +   L
Sbjct: 951  LVGEEVMENWTVRELLLLQVEEQKT-LSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWL 1009

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
             Q M G  P       VHCSAG+GRTGT I +D++L Q++ EG    +     V+ +R+ 
Sbjct: 1010 DQTMEGGPP------IVHCSAGVGRTGTLIALDVLLRQLQSEGL---LGPFSFVRKMRES 1060

Query: 549  RSGMVQNEAQYKFIYMAVLEFIETEKQ 575
            R  MVQ EAQY F++  +L F++   Q
Sbjct: 1061 RPLMVQTEAQYVFLHQCILRFLQQSAQ 1087



 Score = 57.6 bits (133), Expect = 9e-07
 Identities = 29/66 (43%), Positives = 45/66 (68%), Gaps = 4/66 (6%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF +E++ L ++ + Q   +M  S  EN  KNRY+N++P+D +RV LK I  +  PGSDY
Sbjct: 821 GFADEYQQLSLVGHSQ--SQMVASASENNAKNRYRNVLPYDWSRVPLKPIHEE--PGSDY 876

Query: 261 INANYI 266
           INA+++
Sbjct: 877 INASFM 882


>UniRef50_Q9W323 Cluster: CG32697-PA, isoform A; n=5; Drosophila
           melanogaster|Rep: CG32697-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 827

 Score =  140 bits (338), Expect = 1e-31
 Identities = 75/207 (36%), Positives = 114/207 (55%), Gaps = 10/207 (4%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKKYTI 427
           YI+TQG L  T   FW MIW++   +I+MTT+ +ERG+VKC +YW    ++ +    Y +
Sbjct: 602 YISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHV 661

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
                    DY +   L  +  +T   R + H+ FT+WPD+ VPS    +LN L  V  +
Sbjct: 662 RTISVECNEDYMVAS-LELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREK 720

Query: 488 LQQIMTG-----TDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
             Q++ G        P    + VHCSAGIGRTGTFI +D+ + ++   G     DI  TV
Sbjct: 721 QAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVG---TADIRGTV 777

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEF 569
           + +R QR+  +Q   QY F ++A++E+
Sbjct: 778 EKIRSQRAYSIQMPDQYVFCHLALIEY 804



 Score = 44.8 bits (101), Expect = 0.007
 Identities = 19/39 (48%), Positives = 28/39 (71%), Gaps = 2/39 (5%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N+ KNRY +++ +DH+RV+L     DG   SDYINAN++
Sbjct: 557 NLTKNRYTDVLCYDHSRVVLAH--EDGDEPSDYINANFV 593


>UniRef50_P18433 Cluster: Receptor-type tyrosine-protein phosphatase
           alpha precursor; n=81; Chordata|Rep: Receptor-type
           tyrosine-protein phosphatase alpha precursor - Homo
           sapiens (Human)
          Length = 802

 Score =  140 bits (338), Expect = 1e-31
 Identities = 78/203 (38%), Positives = 109/203 (53%), Gaps = 15/203 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
           +IA QG    T+  FW MIW+++   I+M T   ER + KC +YWPD           + 
Sbjct: 310 FIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPD-QGCWTYGNIRVS 368

Query: 429 NEFESSTPDYTLRRFLVTKKDETT---VKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            E  +   DYT+R+F + +  + T    +R I  FHFT+WPD  VP  P  +L  L  V 
Sbjct: 369 VEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVK 428

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
                     +P     + VHCSAG+GRTGTF+VID +LD +  E    ++D++  V  +
Sbjct: 429 --------ACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTER---KVDVYGFVSRI 477

Query: 546 RDQRSGMVQNEAQYKFIYMAVLE 568
           R QR  MVQ + QY FIY A+LE
Sbjct: 478 RAQRCQMVQTDMQYVFIYQALLE 500



 Score =  136 bits (329), Expect = 2e-30
 Identities = 79/204 (38%), Positives = 114/204 (55%), Gaps = 12/204 (5%)

Query: 368 TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI 427
           +YIA+QG L  TI  FW MIW+     I+M T+  ERG+ KC +YWP  +        T+
Sbjct: 602 SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPS-DGLVSYGDITV 660

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
             + E     YT+R  LVT   E    R I  FHF  WP+  +PS+   +++I+  V  +
Sbjct: 661 ELKKEEECESYTVRDLLVTNTRENK-SRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQ 719

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
            QQ  +G  P     + VHCSAG GRTGTF  +  +L++++ EG    +D+ +TV+ +R 
Sbjct: 720 QQQ--SGNHP-----ITVHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRL 769

Query: 548 QRSGMVQNEAQYKFIYMAVLEFIE 571
           QR  MVQ   QY+F Y  V E+I+
Sbjct: 770 QRPHMVQTLEQYEFCYKVVQEYID 793



 Score = 54.8 bits (126), Expect = 6e-06
 Identities = 26/43 (60%), Positives = 32/43 (74%), Gaps = 2/43 (4%)

Query: 224 SKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           SK EN  KNRY NI+P+DH+RV L   P +G P SDYINA++I
Sbjct: 261 SKEENKEKNRYVNILPYDHSRVHL--TPVEGVPDSDYINASFI 301



 Score = 44.0 bits (99), Expect = 0.012
 Identities = 28/99 (28%), Positives = 51/99 (51%), Gaps = 8/99 (8%)

Query: 168 FNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPE 227
           +  T ++V    T ++++  +  G   +     G  EEF+ L  ++ +Q      G+ P 
Sbjct: 504 YGDTELEVTSLETHLQKIYNKIPGTSNN-----GLEEEFKKLTSIK-IQNDKMRTGNLPA 557

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N++KNR   IIP++  RVI+      G   +DY+NA++I
Sbjct: 558 NMKKNRVLQIIPYEFNRVIIP--VKRGEENTDYVNASFI 594


>UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like
            precursor; n=6; Caenorhabditis|Rep: Tyrosine-protein
            phosphatase Lar-like precursor - Caenorhabditis elegans
          Length = 2200

 Score =  140 bits (338), Expect = 1e-31
 Identities = 85/212 (40%), Positives = 116/212 (54%), Gaps = 15/212 (7%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-NKTEVVKKY 425
            ++YIATQG L  T   FW M+W+E    I+M T   ER +VKC++YWP     T    + 
Sbjct: 1713 RSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEV 1772

Query: 426  TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            T+L     +   YT+R   +    E  V R I H  +TAWPDH VP  P   L       
Sbjct: 1773 TLLESVHLA--HYTMRTMRLKMVGEPEV-REIKHLQYTAWPDHGVPDHPTPFLIF----- 1824

Query: 486  YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
              L+++ T  +P     +  HCSAGIGRTG FIVID +L+++R   +D  +DI+  V  +
Sbjct: 1825 --LKRVKT-LNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLR---YDNTVDIYGCVTAL 1878

Query: 546  RDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
            R QRS MVQ E QY FI+ AVL+ + +    V
Sbjct: 1879 RAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEV 1910



 Score =  118 bits (284), Expect = 4e-25
 Identities = 69/202 (34%), Positives = 100/202 (49%), Gaps = 11/202 (5%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YIATQ   + T   FW  IW+ +  II M  +  ERG+ +C  YWP L     V    + 
Sbjct: 2003 YIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWP-LETGVQVGMLVVE 2061

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
               E     Y LR F ++  +   V RT+  FHF  WPD   P      L+ +  V+   
Sbjct: 2062 PMAEYDMKHYHLREFRISDINTREV-RTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTY 2120

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
             Q   G   P    + VHC +G GRT  FI + +ILD++R E     +D+  TV+++R +
Sbjct: 2121 AQF--GCTGP----ITVHCCSGAGRTAVFIALSIILDRMRAEHV---VDVFTTVKLLRTE 2171

Query: 549  RSGMVQNEAQYKFIYMAVLEFI 570
            R  M+Q   QY F+Y+A  E++
Sbjct: 2172 RQNMIQEPEQYHFLYLAAYEYL 2193



 Score = 58.0 bits (134), Expect = 7e-07
 Identities = 30/66 (45%), Positives = 40/66 (60%), Gaps = 5/66 (7%)

Query: 201  GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
            GF  EFE++   E  Q F     S   N  KNRY N+  +DH+RV+L ++  +G PG DY
Sbjct: 1646 GFQSEFESI---ETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNV--EGYPGMDY 1700

Query: 261  INANYI 266
            INANY+
Sbjct: 1701 INANYV 1706



 Score = 41.9 bits (94), Expect = 0.047
 Identities = 20/41 (48%), Positives = 28/41 (68%), Gaps = 2/41 (4%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            P N  KNR  + +P+D  RVI++ +P  G  GSDYINA++I
Sbjct: 1956 PVNRPKNRMLSAVPYDSNRVIMRLLP--GADGSDYINASWI 1994


>UniRef50_UPI00015B4D57 Cluster: PREDICTED: similar to
           ENSANGP00000010449; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000010449 - Nasonia
           vitripennis
          Length = 746

 Score =  139 bits (337), Expect = 2e-31
 Identities = 81/228 (35%), Positives = 120/228 (52%), Gaps = 13/228 (5%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
           N  YIATQG L  T   FW ++W++   +I+M T+  E G+  C RYWPD   +E+   Y
Sbjct: 512 NPAYIATQGPLPQTAADFWQLVWEQGSVVIVMLTRLTEEGQAMCHRYWPD-EGSELYHIY 570

Query: 426 TI-LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
            + L        DY +R F + K   T   RT+  FHF +WP + VP         LL+ 
Sbjct: 571 EVHLVSEHIWCDDYLVRSFYL-KNLRTGETRTVTQFHFLSWPQNGVPKSS----KTLLEF 625

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
             ++ +   G   P    + VHCS G GRTGT+ +IDM+L+++ K     EIDI  T++ 
Sbjct: 626 RRKVNKSYRGRSCP----IIVHCSDGAGRTGTYCLIDMVLNRMAKGA--KEIDIAATLEH 679

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDSPRARS 592
           +RDQR+ MV  + QY+F+ MAV E +    + + +  E   D  +  S
Sbjct: 680 IRDQRADMVATKQQYEFVLMAVAEEVHAILKSLPIVAEKPSDGEKPSS 727


>UniRef50_P35832 Cluster: Tyrosine-protein phosphatase 99A
           precursor; n=18; Endopterygota|Rep: Tyrosine-protein
           phosphatase 99A precursor - Drosophila melanogaster
           (Fruit fly)
          Length = 1301

 Score =  139 bits (337), Expect = 2e-31
 Identities = 77/208 (37%), Positives = 120/208 (57%), Gaps = 19/208 (9%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
           +I TQG L  T   FW MIW++ V II+M T  +ERG+ KC+ YWP D  +T  V +  +
Sbjct: 548 FIGTQGPLPDTFDCFWRMIWEQRVAIIVMITNLVERGRRKCDMYWPKDGVETYGVIQVKL 607

Query: 428 LNEFESSTPDYTLRRFLV-----TKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
           + E   ST  YT+R   +      KK +   ++ +Y +H+T WPDH  P  P  VLN + 
Sbjct: 608 IEEEVMST--YTVRTLQIKHLKLKKKKQCNTEKLVYQYHYTNWPDHGTPDHPLPVLNFV- 664

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
                  +  +  +P     + VHCSAG+GRTGT+IV+D +L QI+++     +++   +
Sbjct: 665 -------KKSSAANPAEAGPIVVHCSAGVGRTGTYIVLDAMLKQIQQKNI---VNVFGFL 714

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
           + +R QR+ +VQ E QY F++ A++E I
Sbjct: 715 RHIRAQRNFLVQTEEQYIFLHDALVEAI 742



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 31/146 (21%), Positives = 63/146 (43%), Gaps = 11/146 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           + +I TQ  ++ TI  FW M+W  + + +++ +       +   ++WPD         Y 
Sbjct: 831 RDFIVTQHPMAHTIKDFWQMVWDHNAQTVVLLS---SLDDINFAQFWPDEATPIESDHYR 887

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           +    +++  DY  R F++ +  +   + T+   H  +WP+    S P  + + ++DV+ 
Sbjct: 888 VKFLNKTNKSDYVSRDFVI-QSIQDDYELTVKMLHCPSWPE---MSNPNSIYDFIVDVHE 943

Query: 487 RLQQIMTG----TDPPAQAVVCVHCS 508
           R      G     D    A  C  C+
Sbjct: 944 RCNDYRNGPIVIVDRYGGAQACTFCA 969



 Score = 48.0 bits (109), Expect = 7e-04
 Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 1/66 (1%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF  E+E +Q               PEN RKNRY NI  +DH+RV L   P       DY
Sbjct: 475 GFSREYEAIQNECISDDLPCEHSQHPENKRKNRYLNITAYDHSRVHLHPTPGQ-KKNLDY 533

Query: 261 INANYI 266
           INAN+I
Sbjct: 534 INANFI 539


>UniRef50_Q64512 Cluster: Tyrosine-protein phosphatase non-receptor
            type 13; n=19; Eumetazoa|Rep: Tyrosine-protein
            phosphatase non-receptor type 13 - Mus musculus (Mouse)
          Length = 2453

 Score =  139 bits (337), Expect = 2e-31
 Identities = 82/212 (38%), Positives = 116/212 (54%), Gaps = 17/212 (8%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKYTI 427
            YIA QG L TT+  FW M+W+++  +I M T+E+E  K+KC+RYWP  L  T +  +   
Sbjct: 2246 YIACQGPLPTTVGDFWQMVWEQNSTVIAMMTQEVEGEKIKCQRYWPSILGTTTMANERLR 2305

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L           + R +  +  +T   R I H +FTAWPDH  PS+P    ++L  ++Y 
Sbjct: 2306 LALLRMQQLKGFIVRVMALEDIQTGEVRHISHLNFTAWPDHDTPSQPD---DLLTFISYM 2362

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                 +G        V  HCSAGIGR+GT I ID++L  I +   D E DI   V+ +R 
Sbjct: 2363 RHIRRSGP-------VITHCSAGIGRSGTLICIDVVLGLISQ---DLEFDISDLVRCMRL 2412

Query: 548  QRSGMVQNEAQYKFIY---MAVLEFIETEKQR 576
            QR GMVQ E QY F Y   + VL  ++ E+Q+
Sbjct: 2413 QRHGMVQTEGQYVFCYQVILYVLTHLQAEEQK 2444



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 30/64 (46%), Positives = 38/64 (59%), Gaps = 9/64 (14%)

Query: 204  EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
            +E E LQ ++ L     + G   EN RKNRYKNI+P+D TRV      P G  G  YINA
Sbjct: 2182 KELENLQELKPLD--QCLIGQTKENRRKNRYKNILPYDTTRV------PLGDEGG-YINA 2232

Query: 264  NYIR 267
            ++IR
Sbjct: 2233 SFIR 2236


>UniRef50_UPI0000F20574 Cluster: PREDICTED: similar to glomerular
            mesangial cell receptor protein-tyrosine phosphatase;
            n=1; Danio rerio|Rep: PREDICTED: similar to glomerular
            mesangial cell receptor protein-tyrosine phosphatase -
            Danio rerio
          Length = 1253

 Score =  139 bits (336), Expect = 2e-31
 Identities = 70/206 (33%), Positives = 115/206 (55%), Gaps = 15/206 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            +IATQG L +T+  FW MIW+   + I+M T+  E+G+++C +YWP+ NK   V    I+
Sbjct: 1026 FIATQGPLPSTVADFWRMIWETGTKTIVMLTQCFEKGRIRCHQYWPEDNKPVTVFADIII 1085

Query: 429  NEF-ESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
             +  E   PD+T+R   V +     +   ++HF++T+WP+H VP     ++  +  V   
Sbjct: 1086 TKLTEDVRPDWTVRALKVERHGSYMI---VHHFNYTSWPEHGVPESSSTLVQFVKAVRSN 1142

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                  G +      + VHCSAG+GRTG FI +D ++  +R   F   +DI+  V  +R 
Sbjct: 1143 -----RGHE---NTTIVVHCSAGVGRTGVFIALDHLIQHLRDHEF---VDIYGLVAELRS 1191

Query: 548  QRSGMVQNEAQYKFIYMAVLEFIETE 573
            +R  MVQN AQY F++ + L+ +  +
Sbjct: 1192 ERMCMVQNLAQYMFLHQSTLDLLSAK 1217



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 28/65 (43%), Positives = 38/65 (58%), Gaps = 4/65 (6%)

Query: 202  FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
            F EEF  L  +  LQ     +   P N  KNR+ NI P++++RV L   P  G PGSDYI
Sbjct: 957  FQEEFAELPKL--LQDLATSDADLPWNRSKNRFTNIKPYNNSRVKLLSEP--GMPGSDYI 1012

Query: 262  NANYI 266
            NA+++
Sbjct: 1013 NASFV 1017


>UniRef50_UPI0000DB795D Cluster: PREDICTED: similar to Protein
            tyrosine phosphatase 69D CG10975-PB, isoform B; n=2;
            Apocrita|Rep: PREDICTED: similar to Protein tyrosine
            phosphatase 69D CG10975-PB, isoform B - Apis mellifera
          Length = 1435

 Score =  139 bits (336), Expect = 2e-31
 Identities = 73/207 (35%), Positives = 112/207 (54%), Gaps = 16/207 (7%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K +I  QG +  T+  +W MIW++ + +I+M T   E  K KC +YWPD  +T+     T
Sbjct: 943  KKFICAQGPMENTVCDYWRMIWEQHLELILMLTNLEEYSKTKCAKYWPDKGETKNFGDIT 1002

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN- 485
            + +  E +  DY +R   +T+  E    RTI  +HF  W D   P  P  +L  +  VN 
Sbjct: 1003 VEHVRERAYSDYVVRELKMTRLGERDA-RTIIQYHFLVWKDFMAPEHPHAILRFIKRVNE 1061

Query: 486  -YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
             Y L+          +  + VHCSAG+GRTGT + +D +L Q+ +EG   ++ I  TV  
Sbjct: 1062 AYSLE----------KGPILVHCSAGVGRTGTLVALDSLLQQLAEEG---QVSIFNTVCD 1108

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFIE 571
            +R QR+ +VQ+  QY FIY A++E  +
Sbjct: 1109 LRHQRNFLVQSLKQYIFIYRALMEMAQ 1135



 Score =  105 bits (253), Expect = 3e-21
 Identities = 69/207 (33%), Positives = 110/207 (53%), Gaps = 19/207 (9%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
            +++++ TQ  L TTI  FW MI ++ +  I+M + ++  G  KC RYWPD    E    +
Sbjct: 1232 SESFVITQDPLDTTIADFWRMISEQCISTIVMLS-DLNEGPRKCPRYWPD---EETAYDH 1287

Query: 426  TILNEFES-STPDYTLRRFLV--TKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
              +   +S S P YT R F V  TK DE+ V  T Y +H   WP   V  E   V   L+
Sbjct: 1288 IRVRYIQSESCPYYTRREFCVSNTKTDESVVV-TQYQYH--GWPT--VEGEVPEVTRGLI 1342

Query: 483  DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
            ++   + Q +T  D  +   + VHCS G  R+  F+ + +++ Q+R E     +DI  T 
Sbjct: 1343 EL---VNQTLTN-DTESSGSLVVHCSYGSDRSSMFVALSILVQQLRTEK---RVDIFTTT 1395

Query: 543  QMVRDQRSGMVQNEAQYKFIYMAVLEF 569
            + +R QR GM+   AQY+F++ A++ +
Sbjct: 1396 KKLRSQRHGMISTFAQYEFLHRAIVNY 1422



 Score = 44.4 bits (100), Expect = 0.009
 Identities = 29/66 (43%), Positives = 36/66 (54%), Gaps = 4/66 (6%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF  EFE L      +     E    EN+ KNRY +I  +D TRV L  +  DG  GSDY
Sbjct: 875 GFQHEFELLPDRFTDRTTRASEAR--ENLYKNRYPDIKCYDQTRVRLAQM--DGICGSDY 930

Query: 261 INANYI 266
           INAN++
Sbjct: 931 INANFV 936



 Score = 42.3 bits (95), Expect = 0.035
 Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 6/78 (7%)

Query: 204  EEFETLQ-MMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYIN 262
            EE++ +  ++E+ + F    G   EN  KNR + IIP+D  RVIL  +P  G   S YIN
Sbjct: 1167 EEYDKINSVLEDRKSFS--VGGGEENKSKNRSELIIPYDRNRVILTPVP--GREHSTYIN 1222

Query: 263  ANYIR-CDSMDSISDSQE 279
            A++I   D+ +S   +Q+
Sbjct: 1223 ASFIEGYDNSESFVITQD 1240


>UniRef50_Q4RHI4 Cluster: Chromosome 19 SCAF15047, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 19 SCAF15047, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 703

 Score =  139 bits (336), Expect = 2e-31
 Identities = 74/210 (35%), Positives = 114/210 (54%), Gaps = 12/210 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV-KKY 425
           +TYIATQG L  T+  FW M W+ +V +I+M  +E E G+ KCERY+P L +  V    +
Sbjct: 70  ETYIATQGPLPNTVIDFWRMNWEYNVAVIVMACREFEMGRKKCERYYPQLKEEPVTFGPF 129

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            I  E E +  DY +R   V  ++ET   R I  FH+  WPDH VPS      + +LD+ 
Sbjct: 130 RISCESEQARTDYLIRALTVEYENET---RRITQFHYLNWPDHDVPSS----FDSILDMI 182

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
             +++    +  P    +CVHCSAG GRTG    ID   + ++      + ++ R +Q +
Sbjct: 183 GLMREYQDHSGVP----ICVHCSAGCGRTGAICAIDHTWNLLKAGKIPEDFNVFRLIQEM 238

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETEKQ 575
           R QR   VQ + QY+ ++ A+ +  + + Q
Sbjct: 239 RTQRHSAVQTKEQYELVHKAIAQLFKKQLQ 268



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 24/52 (46%), Positives = 35/52 (67%), Gaps = 2/52 (3%)

Query: 216 QLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           +++    G K EN++KNRYK+I+PFDH+RV L          +DYINAN+I+
Sbjct: 15  KIYPTNAGEKEENVKKNRYKDILPFDHSRVKLG--LKTSNQDADYINANFIK 64


>UniRef50_Q12923 Cluster: Tyrosine-protein phosphatase non-receptor
            type 13; n=12; Amniota|Rep: Tyrosine-protein phosphatase
            non-receptor type 13 - Homo sapiens (Human)
          Length = 2485

 Score =  139 bits (336), Expect = 2e-31
 Identities = 80/200 (40%), Positives = 110/200 (55%), Gaps = 14/200 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKYTI 427
            YIA QG L TT+  FW MIW++   +I M T+E+E  K+KC+RYWP+ L KT +V     
Sbjct: 2279 YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLR 2338

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L           + R +  +  +T   R I H +FTAWPDH  PS+P    ++L  ++Y 
Sbjct: 2339 LALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPD---DLLTFISYM 2395

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                 +G        +  HCSAGIGR+GT I ID++L  I +   D + DI   V+ +R 
Sbjct: 2396 RHIHRSGP-------IITHCSAGIGRSGTLICIDVVLGLISQ---DLDFDISDLVRCMRL 2445

Query: 548  QRSGMVQNEAQYKFIYMAVL 567
            QR GMVQ E QY F Y  +L
Sbjct: 2446 QRHGMVQTEDQYIFCYQVIL 2465



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 29/64 (45%), Positives = 38/64 (59%), Gaps = 9/64 (14%)

Query: 204  EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
            +E E LQ ++ L     + G   EN RKNRYKNI+P+D TRV      P G  G  YINA
Sbjct: 2215 KELENLQELKPLD--QCLIGQTKENRRKNRYKNILPYDATRV------PLGDEGG-YINA 2265

Query: 264  NYIR 267
            ++I+
Sbjct: 2266 SFIK 2269


>UniRef50_P08575 Cluster: Leukocyte common antigen precursor; n=106;
           Amniota|Rep: Leukocyte common antigen precursor - Homo
           sapiens (Human)
          Length = 1304

 Score =  139 bits (336), Expect = 2e-31
 Identities = 74/214 (34%), Positives = 113/214 (52%), Gaps = 12/214 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK-TEVVKKY 425
           + YIA QG    T+  FW MIW++   +I+M T+  E  + KC  YWP + + T      
Sbjct: 718 RKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDV 777

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            +        PDY +++  +  K E    R + H  FT+WPDH VP +P    ++LL + 
Sbjct: 778 VVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDP----HLLLKLR 833

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
            R+         P    + VHCSAG+GRTGT+I ID +L+ +  E    ++D++  V  +
Sbjct: 834 RRVNAFSNFFSGP----IVVHCSAGVGRTGTYIGIDAMLEGLEAEN---KVDVYGYVVKL 886

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGL 579
           R QR  MVQ EAQY  I+ A++E+ +  +  V L
Sbjct: 887 RRQRCLMVQVEAQYILIHQALVEYNQFGETEVNL 920



 Score = 97.9 bits (233), Expect = 7e-19
 Identities = 62/197 (31%), Positives = 103/197 (52%), Gaps = 10/197 (5%)

Query: 370  IATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVK-CERYWPDLNKTEVVKKYTIL 428
            IA QG L  TI  FW MI+Q  V++I+M T E++ G  + C +YW +  +T    +  + 
Sbjct: 1031 IAAQGPLKETIGDFWQMIFQRKVKVIVMLT-ELKHGDQEICAQYWGEGKQTYGDIEVDLK 1089

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
            +  +SST  YTLR F + +  +    RT+Y + +T W   ++P+EP  +++++  V  +L
Sbjct: 1090 DTDKSST--YTLRVFEL-RHSKRKDSRTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKL 1146

Query: 489  QQ--IMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
             Q     G        + +HC  G  +TG F  +  +L+    E     +DI + V+ +R
Sbjct: 1147 PQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV---VDIFQVVKALR 1203

Query: 547  DQRSGMVQNEAQYKFIY 563
              R GMV    QY+F+Y
Sbjct: 1204 KARPGMVSTFEQYQFLY 1220



 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 4/65 (6%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F  EF+++  +     F   E  KP N  KNRY +I+P+D+ RV L +I  +G  GS+YI
Sbjct: 651 FLAEFQSIPRV--FSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEI--NGDAGSNYI 706

Query: 262 NANYI 266
           NA+YI
Sbjct: 707 NASYI 711


>UniRef50_Q179W1 Cluster: Protein-tyrosine phosphatase n9; n=1;
           Aedes aegypti|Rep: Protein-tyrosine phosphatase n9 -
           Aedes aegypti (Yellowfever mosquito)
          Length = 681

 Score =  138 bits (335), Expect = 3e-31
 Identities = 74/207 (35%), Positives = 113/207 (54%), Gaps = 10/207 (4%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYW-PDLNKTEVVKKYTI 427
           YI+TQG L  T Y FW M+W++   +I+MTT+ +ERG+VKC +YW P          Y +
Sbjct: 456 YISTQGPLPKTSYDFWRMVWEQHCLVIVMTTRVMERGRVKCGQYWEPTEGGVVEYGCYQV 515

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
                 +  DYT+   L  K  +T   R + H+ FT+WPD+ VP+    +LN L     +
Sbjct: 516 RTLSVEANEDYTVAE-LEVKNSKTDEVRCVSHWQFTSWPDYGVPASARAMLNFLQRAREK 574

Query: 488 LQQIMTG-----TDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
             +++          P    + VHCSAGIGRTGTFI +D+ + ++   G     DI  TV
Sbjct: 575 QAEMVKSLGDLWAGHPRGPPMVVHCSAGIGRTGTFITLDICISRLEDVG---TADIKGTV 631

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEF 569
           + +R QR+  +Q   QY F ++A++E+
Sbjct: 632 EKIRAQRAYSIQMPDQYVFCHLALIEY 658



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 20/39 (51%), Positives = 28/39 (71%), Gaps = 2/39 (5%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N+ KNRY +++ +DH+RVIL     D  P SDYINAN++
Sbjct: 411 NLAKNRYTDVLCYDHSRVILSQEADD--PTSDYINANFV 447


>UniRef50_A7SX30 Cluster: Predicted protein; n=7; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 577

 Score =  138 bits (335), Expect = 3e-31
 Identities = 78/210 (37%), Positives = 113/210 (53%), Gaps = 17/210 (8%)

Query: 362 VHVYNKT---YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK 418
           +H Y+ T   +IA+QG L      FW M+W+++ + I+M T  +E GK KC +YWPD  K
Sbjct: 81  IHGYDGTPRSFIASQGPLPPAFEDFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPD--K 138

Query: 419 TEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVL 478
           TE     T+         +Y +R F+++K  ++   R +  FHFT WPD  VP     VL
Sbjct: 139 TETYGGVTVTLHQSEIFAEYEIRTFILSKAKQSG-SRMVRQFHFTVWPDKGVPQYATAVL 197

Query: 479 NILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
                     ++ +   +P     V VHCSAG+GRTG +IVID +L+Q +K      +DI
Sbjct: 198 --------AFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKKSR---TVDI 246

Query: 539 HRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
              +  +R  R  MVQ + QY FI+ AVLE
Sbjct: 247 RNYLIALRKDRPHMVQTKEQYSFIHSAVLE 276



 Score = 92.7 bits (220), Expect = 3e-17
 Identities = 62/213 (29%), Positives = 104/213 (48%), Gaps = 19/213 (8%)

Query: 363 HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
           H     +IATQ  L  T+  FW M+   D+  I+M     E  + +  +YWPD   T+  
Sbjct: 371 HRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPKYWPDHGPTKYG 429

Query: 423 K-KYTILNEFESSTPDYTLRRFLVTKKDETTVKRT--IYHFHFTAWPDHRVPSEPGRVLN 479
               ++L++ E    D    +  VT+K    V+RT  + H H  +WPD  +P     VL+
Sbjct: 430 HIGVSVLSKQEQG--DVICTKLKVTRKK---VRRTHEVRHLHHVSWPDKCIPEVACSVLD 484

Query: 480 ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
           +L +     QQ          A V V CS G+GR+GTF  I  +L++++ E     ID+ 
Sbjct: 485 LLDEAQTSQQQC-------GNAPVLVQCSNGVGRSGTFCAISSVLERLKTEQV---IDVF 534

Query: 540 RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
           + ++ +R    G V++  QY F Y  + +++++
Sbjct: 535 QVIKRIRVNLPGAVESPTQYMFCYQIIQKYLDS 567



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 25/54 (46%), Positives = 35/54 (64%), Gaps = 2/54 (3%)

Query: 213 ENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           +N Q F      KP N  KNRY NI+ +DH+RV+L+ +  +G   SDYINA++I
Sbjct: 30  DNGQQFPWEAARKPANKNKNRYANIVAYDHSRVVLERV--NGDEDSDYINASFI 81



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 25/57 (43%), Positives = 36/57 (63%), Gaps = 2/57 (3%)

Query: 210 QMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           Q  +N Q F      KP N  KNRY NI+ +DH+R++L+ +  +G   SDYINA++I
Sbjct: 314 QKFDNGQQFPWEAARKPANKNKNRYANIVAYDHSRLVLERV--NGNEDSDYINASFI 368


>UniRef50_UPI000065DD5D Cluster: Homolog of Homo sapiens "protein
            tyrosine phosphatase, non-receptor type 13 isoform 2;
            n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens
            "protein tyrosine phosphatase, non-receptor type 13
            isoform 2 - Takifugu rubripes
          Length = 2538

 Score =  138 bits (333), Expect = 5e-31
 Identities = 77/200 (38%), Positives = 108/200 (54%), Gaps = 14/200 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKT-EVVKKYTI 427
            YIA QG L TT+  FW M+ ++   +I M T+E+E GKVKC+RYWPD   T E+V     
Sbjct: 2342 YIACQGPLPTTLSDFWQMVLEQKSNVIAMMTREVEGGKVKCQRYWPDTPMTAEMVDDRLQ 2401

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            +   +    D    R +  K  +T+  + + H ++T WPDH  P++P  +L     ++Y 
Sbjct: 2402 ITLIKDQYLDNFGIRLIEVKDIQTSESQLVTHLNYTGWPDHGTPTQPEHLLTF---ISYM 2458

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                 +G        +  HCSAGIGR+GT I ID +L  I K   D + DI   V+ +R 
Sbjct: 2459 RHIHRSGP-------IITHCSAGIGRSGTLICIDTVLGLISK---DADFDISDVVRNMRL 2508

Query: 548  QRSGMVQNEAQYKFIYMAVL 567
            QR GMVQ E QY F Y  +L
Sbjct: 2509 QRHGMVQTEDQYIFCYQVIL 2528



 Score = 52.4 bits (120), Expect = 3e-05
 Identities = 31/69 (44%), Positives = 41/69 (59%), Gaps = 9/69 (13%)

Query: 204  EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
            +EF+ LQ +E L   D +     EN +KNRYKN++PFD TRV+L      G  G  YINA
Sbjct: 2278 QEFDNLQNLEPLD--DCLIAQTKENKKKNRYKNVVPFDTTRVLL------GKDGG-YINA 2328

Query: 264  NYIRCDSMD 272
            N+I+    D
Sbjct: 2329 NFIKMPVKD 2337


>UniRef50_P35236 Cluster: Tyrosine-protein phosphatase non-receptor
           type 7; n=15; Mammalia|Rep: Tyrosine-protein phosphatase
           non-receptor type 7 - Homo sapiens (Human)
          Length = 360

 Score =  138 bits (333), Expect = 5e-31
 Identities = 73/197 (37%), Positives = 110/197 (55%), Gaps = 15/197 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           K YIATQG +  T+  FW M+WQE+V +I+M T ++  GK KC  YWP   + E    + 
Sbjct: 163 KVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLT-QLREGKEKCVHYWP--TEEETYGPFQ 219

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           I  +     P+YT+R+  +  ++E   +R++ H  F+AWPDH+ P   G +L ++ +V  
Sbjct: 220 IRIQDMKECPEYTVRQLTIQYQEE---RRSVKHILFSAWPDHQTPESAGPLLRLVAEVE- 275

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
             +   T   P     + VHCSAGIGRTG FI   +   Q++  G   E+DI   V  +R
Sbjct: 276 --ESPETAAHP---GPIVVHCSAGIGRTGCFIATRIGCQQLKARG---EVDILGIVCQLR 327

Query: 547 DQRSGMVQNEAQYKFIY 563
             R GM+Q   QY+F++
Sbjct: 328 LDRGGMIQTAEQYQFLH 344



 Score = 35.1 bits (77), Expect = 5.4
 Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 2/42 (4%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           P +  K+RYK I+P   +RV L           DYINANYIR
Sbjct: 117 PGHASKDRYKTILPNPQSRVCLG--RAQSQEDGDYINANYIR 156


>UniRef50_UPI0000F21610 Cluster: PREDICTED: similar to protein
            tyrosine phosphatase, receptor-type, Z polypeptide 1,;
            n=2; Danio rerio|Rep: PREDICTED: similar to protein
            tyrosine phosphatase, receptor-type, Z polypeptide 1, -
            Danio rerio
          Length = 1814

 Score =  137 bits (332), Expect = 7e-31
 Identities = 81/220 (36%), Positives = 129/220 (58%), Gaps = 21/220 (9%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTE----- 420
            NK YIA QG L ++   FW M+W+++V +I+M T  +E+G+ KC++YWP  N+ E     
Sbjct: 1290 NKAYIAAQGPLKSSTPDFWRMVWEQNVGVIVMITNLVEKGRKKCDQYWPLENQEEYGCFL 1349

Query: 421  -VVKKYTILNEFESSTPDYTLRRFLVTKKDE--TTVKRTIYHFHFTAWPDHRVPSEPGRV 477
              VK   +L  +   T  +TLR   + K  +   + +RT+  +H+T WPD  VP     V
Sbjct: 1350 VTVKSTNVLAYYTKRT--FTLRNTSIKKGSQRYRSNERTVTQYHYTQWPDMGVPE---YV 1404

Query: 478  LNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEID 537
            L +L  V Y+  +  T    P    + VHCSAG+GRTGT+IV+D +L QI+++G    ++
Sbjct: 1405 LPVLSFV-YKSSKAQTDGMGP----MVVHCSAGVGRTGTYIVLDSMLKQIKEKG---TVN 1456

Query: 538  IHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
            I   ++ +R QR+ +VQ E QY F + A++E I +++  V
Sbjct: 1457 IMGFLKHIRTQRNYLVQTEEQYIFTHDALVEAILSQETEV 1496



 Score = 66.1 bits (154), Expect = 3e-09
 Identities = 50/241 (20%), Positives = 106/241 (43%), Gaps = 22/241 (9%)

Query: 348  IPKSATETENGVPTVHVY----NKTYIATQGCLSTTIYPFWSMIWQEDVRIII-MTTKEI 402
            +  SA ET + +   +V     NK +I TQ  L  T+   W M+W ++ ++I+ +  +  
Sbjct: 1563 VSSSAGETSDYINASYVMGYRQNKEFIITQNPLPNTVKDLWRMVWDQNSQVIVSLPDRSS 1622

Query: 403  ERGKVKCERYWPDLNKTEVVKKYTILNEFES----STPDYTLRRFLVTKKDETTVKRTIY 458
                 +   +WP  ++  + + +++    E     S  D  + +  + +  +      + 
Sbjct: 1623 TTEDSEPVIFWPTRDQPIIYETFSVSLRGEDHVCLSNEDMLIVQDYILEATKDDFVLEVK 1682

Query: 459  HFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFI 518
            HF    WP+   P  P   ++ + ++   +Q+  +  D P    + +H   G    GTF 
Sbjct: 1683 HFRSPRWPN---PDSP---ISSVFEMIRIIQKEASSKDGP----MVIHDEHGGVTAGTFC 1732

Query: 519  VIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVG 578
             +  +L Q+  E     +D++   +M+   R G+  +  QY+F+Y A+L  + T++    
Sbjct: 1733 ALFTLLQQLEAESV---VDVYMVAKMINLMRPGVFTDIDQYQFLYKAILSLVSTQEDEQA 1789

Query: 579  L 579
            L
Sbjct: 1790 L 1790



 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 23/42 (54%), Positives = 29/42 (69%), Gaps = 1/42 (2%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDI-PPDGPPGSDYINANYI 266
            P+N  KNRY NI+ +DH+RV L  +   DG  G DYINANY+
Sbjct: 1243 PDNKNKNRYVNILAYDHSRVRLAPLNDKDGKSGGDYINANYV 1284


>UniRef50_P18031 Cluster: Tyrosine-protein phosphatase non-receptor
           type 1; n=16; Euteleostomi|Rep: Tyrosine-protein
           phosphatase non-receptor type 1 - Homo sapiens (Human)
          Length = 435

 Score =  137 bits (332), Expect = 7e-31
 Identities = 76/207 (36%), Positives = 112/207 (54%), Gaps = 14/207 (6%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV---- 422
           ++YI TQG L  T   FW M+W++  R ++M  + +E+G +KC +YWP   + E++    
Sbjct: 79  RSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDT 138

Query: 423 -KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
             K T+++E   S   YT+R+ L  +   T   R I HFH+T WPD  VP  P   LN L
Sbjct: 139 NLKLTLISEDIKSY--YTVRQ-LELENLTTQETREILHFHYTTWPDFGVPESPASFLNFL 195

Query: 482 LDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
             V        +G+  P    V VHCSAGIGR+GTF + D  L  + K      +DI + 
Sbjct: 196 FKVRE------SGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKV 249

Query: 542 VQMVRDQRSGMVQNEAQYKFIYMAVLE 568
           +  +R  R G++Q   Q +F Y+AV+E
Sbjct: 250 LLEMRKFRMGLIQTADQLRFSYLAVIE 276



 Score = 37.5 bits (83), Expect = 1.0
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 6/44 (13%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           P+N  +NRY+++ PFDH+R+ L          +DYINA+ I+ +
Sbjct: 38  PKNKNRNRYRDVSPFDHSRIKLHQ------EDNDYINASLIKME 75


>UniRef50_UPI0000DB7D47 Cluster: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 4
           (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG);
           n=3; Endopterygota|Rep: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 4
           (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG)
           - Apis mellifera
          Length = 927

 Score =  136 bits (330), Expect = 1e-30
 Identities = 76/208 (36%), Positives = 118/208 (56%), Gaps = 15/208 (7%)

Query: 359 VPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK 418
           +P   + N+ YIATQG LS+T+  FW M+ +    +++M T  +ERG+ KC +YWP LN+
Sbjct: 704 IPGSGIINR-YIATQGPLSSTVADFWQMVLEAGSTLVVMLTTLVERGRAKCHQYWPALNE 762

Query: 419 TEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVL 478
           T  ++  T+ +  E+    +  R F++    +  V+R I H  + +WPDH VPS+  R  
Sbjct: 763 TLTLRNLTLTSTAENVEDTFIFREFILR---DINVRRNITHMQYCSWPDHGVPSD-WRQF 818

Query: 479 NILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
               +   R++   TG   PA     VHCSAGIGRTG  ++++  L  I        +DI
Sbjct: 819 TTFTE---RVRAARTGIVEPA----VVHCSAGIGRTGVLVLMETALCLIEANQPVYPLDI 871

Query: 539 HRTVQMVRDQRSGMVQNEAQYKFIYMAV 566
              V+ +RDQR+ M+QN +QY+F+  AV
Sbjct: 872 ---VRSMRDQRAMMIQNASQYRFVCEAV 896



 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 25/49 (51%), Positives = 31/49 (63%), Gaps = 5/49 (10%)

Query: 221 MEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           +E  KPEN  KNRY++I P+D TRVIL      G    DYINANY+  +
Sbjct: 660 LESKKPENQNKNRYRDISPYDVTRVILL-----GSASGDYINANYVNME 703


>UniRef50_Q6EHH9 Cluster: Frizzled-8 associated multidomain protein;
            n=3; Xenopus|Rep: Frizzled-8 associated multidomain
            protein - Xenopus laevis (African clawed frog)
          Length = 2500

 Score =  136 bits (329), Expect = 2e-30
 Identities = 75/204 (36%), Positives = 112/204 (54%), Gaps = 14/204 (6%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
            YIA QG L +T+  FW M+W+++  +I M T+EIE GK+KC+RYWP +  +  ++     
Sbjct: 2300 YIACQGPLPSTVSDFWQMVWEQNSSVISMMTQEIEGGKIKCQRYWPEEPGRPLMISNQLQ 2359

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L    +   +  + R L     ++   R I H ++TAWPDH  PS+P ++L     +++ 
Sbjct: 2360 LTLVMTQHLESFVLRVLELHDIQSEEVRQIAHLNYTAWPDHDTPSDPYQLLTF---ISFM 2416

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                 +G        +  HCSAGIGR+GT I ID++L  I K   D E DI   V  +R 
Sbjct: 2417 RHIYKSGP-------IITHCSAGIGRSGTLICIDVMLALISK---DLEFDISNMVHTMRL 2466

Query: 548  QRSGMVQNEAQYKFIYMAVLEFIE 571
            QR GM+Q E QY F Y  +L  ++
Sbjct: 2467 QRHGMIQTEEQYIFCYQVILYILK 2490



 Score = 43.2 bits (97), Expect = 0.020
 Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 9/63 (14%)

Query: 205  EFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINAN 264
            EFE LQ ++       + G   EN +KNRYKNI+P+D TRV L          +DYINA+
Sbjct: 2237 EFELLQDLKPTD--GCLIGQTKENKKKNRYKNILPYDATRVSL-------GAENDYINAS 2287

Query: 265  YIR 267
            +I+
Sbjct: 2288 FIK 2290


>UniRef50_UPI000051A95C Cluster: PREDICTED: similar to ia2
           CG31795-PA, isoform A isoform 2, partial; n=1; Apis
           mellifera|Rep: PREDICTED: similar to ia2 CG31795-PA,
           isoform A isoform 2, partial - Apis mellifera
          Length = 902

 Score =  136 bits (328), Expect = 2e-30
 Identities = 76/204 (37%), Positives = 112/204 (54%), Gaps = 13/204 (6%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
           N  YIATQG L  T   FW ++W++   +I+M T+  E G   C RYWP+   +E+   Y
Sbjct: 684 NPAYIATQGPLPETTADFWQLVWEQGSVVIVMLTRLTEEGIAMCHRYWPE-EGSELYHIY 742

Query: 426 TI-LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
            + L        DY +R F + K   T   RT+  FHF +WP++ +P      +  LL+ 
Sbjct: 743 EVHLVSEHFWCDDYLVRSFYL-KNLRTGETRTVTQFHFLSWPENGIPHS----IKALLEF 797

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
             ++ +   G   P    + VHCS G GRTGT+ +IDM+L+++ K     EIDI  T++ 
Sbjct: 798 RRKINKSYKGRSCP----IVVHCSDGAGRTGTYCLIDMVLNRMMKGA--KEIDIAATLEH 851

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLE 568
           +RDQR  MV  + Q+KF+ MAV E
Sbjct: 852 IRDQRPNMVATKQQFKFVLMAVAE 875



 Score = 36.3 bits (80), Expect = 2.3
 Identities = 19/39 (48%), Positives = 25/39 (64%), Gaps = 2/39 (5%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N++ NR    IP+DH+RVIL D+       SDYINA+ I
Sbjct: 641 NMKCNRPGAAIPYDHSRVILNDLA--NTNNSDYINASTI 677


>UniRef50_A3KPJ4 Cluster: Protein tyrosine phosphatase, receptor
           type, N polypeptide 2; n=4; Danio rerio|Rep: Protein
           tyrosine phosphatase, receptor type, N polypeptide 2 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 650

 Score =  136 bits (328), Expect = 2e-30
 Identities = 78/203 (38%), Positives = 111/203 (54%), Gaps = 11/203 (5%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
           N  YI+ QG L +T+  FW M+W+    +I+M T   E G  +C +YWPD   +++   Y
Sbjct: 448 NPAYISAQGPLPSTVADFWQMVWESGCVVIVMLTPLAENGLKQCHQYWPD-EGSDLYHIY 506

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            +    E    D  L R    K  +T   RT+  FHF +W D  VP E  R    LLD  
Sbjct: 507 EVNLVSEHIWCDDFLVRSFYLKNVQTNETRTVTQFHFLSWMDQNVP-ESART---LLDFR 562

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
            ++ +   G   P    + VHCS G GR+GT+I+IDM+L+++ K     EIDI  T++ +
Sbjct: 563 RKVNKCYRGRSCP----IIVHCSDGAGRSGTYILIDMVLNKMAKGA--KEIDIAATLEHL 616

Query: 546 RDQRSGMVQNEAQYKFIYMAVLE 568
           RDQRSGMVQ + Q++F   AV E
Sbjct: 617 RDQRSGMVQTKDQFEFALTAVAE 639



 Score = 35.5 bits (78), Expect = 4.1
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 2/44 (4%)

Query: 223 GSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           G + +N+++NR   ++ +DH+R ILK    +    SDYINA+ I
Sbjct: 400 GQEEQNVQRNRPHGVLVYDHSRFILK--LENNQSRSDYINASPI 441


>UniRef50_Q6NSL1 Cluster: PTPRN protein; n=4; Eutheria|Rep: PTPRN
           protein - Homo sapiens (Human)
          Length = 950

 Score =  136 bits (328), Expect = 2e-30
 Identities = 79/201 (39%), Positives = 116/201 (57%), Gaps = 13/201 (6%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKKYTI 427
           YIATQG LS TI  FW M+W+    +I+M T  +E G  +C+RYWPD   +   V +  +
Sbjct: 751 YIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGASLYHVYEVNL 810

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
           ++E      D+ +R F + K  +T   RT+  FHF +WP    P+        LLD   +
Sbjct: 811 VSE-HIWCEDFLVRSFYL-KNVQTQETRTLTQFHFLSWPAEGTPAS----TRPLLDFRRK 864

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
           + +   G   P    + VHCS G GRTGT+I+IDM+L+++ K G   EIDI  T++ VRD
Sbjct: 865 VNKCYRGRSCP----IIVHCSDGAGRTGTYILIDMVLNRMAK-GVK-EIDIAATLEHVRD 918

Query: 548 QRSGMVQNEAQYKFIYMAVLE 568
           QR G+V+++ Q++F   AV E
Sbjct: 919 QRPGLVRSKDQFEFALTAVAE 939



 Score = 40.7 bits (91), Expect = 0.11
 Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 2/39 (5%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           NI+KNR+ + +P+DH R+ LK      P  SDYINA+ I
Sbjct: 705 NIKKNRHPDFLPYDHARIKLK--VESSPSRSDYINASPI 741


>UniRef50_Q16849 Cluster: Receptor-type tyrosine-protein
           phosphatase-like N precursor; n=24; Euteleostomi|Rep:
           Receptor-type tyrosine-protein phosphatase-like N
           precursor - Homo sapiens (Human)
          Length = 979

 Score =  136 bits (328), Expect = 2e-30
 Identities = 79/201 (39%), Positives = 116/201 (57%), Gaps = 13/201 (6%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKKYTI 427
           YIATQG LS TI  FW M+W+    +I+M T  +E G  +C+RYWPD   +   V +  +
Sbjct: 780 YIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGASLYHVYEVNL 839

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
           ++E      D+ +R F + K  +T   RT+  FHF +WP    P+        LLD   +
Sbjct: 840 VSE-HIWCEDFLVRSFYL-KNVQTQETRTLTQFHFLSWPAEGTPAS----TRPLLDFRRK 893

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
           + +   G   P    + VHCS G GRTGT+I+IDM+L+++ K G   EIDI  T++ VRD
Sbjct: 894 VNKCYRGRSCP----IIVHCSDGAGRTGTYILIDMVLNRMAK-GVK-EIDIAATLEHVRD 947

Query: 548 QRSGMVQNEAQYKFIYMAVLE 568
           QR G+V+++ Q++F   AV E
Sbjct: 948 QRPGLVRSKDQFEFALTAVAE 968



 Score = 40.7 bits (91), Expect = 0.11
 Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 2/39 (5%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           NI+KNR+ + +P+DH R+ LK      P  SDYINA+ I
Sbjct: 734 NIKKNRHPDFLPYDHARIKLK--VESSPSRSDYINASPI 770


>UniRef50_UPI0001554B98 Cluster: PREDICTED: similar to protein
            tyrosine phosphatase, receptor type Z, polypeptide 1,
            partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
            similar to protein tyrosine phosphatase, receptor type Z,
            polypeptide 1, partial - Ornithorhynchus anatinus
          Length = 1902

 Score =  135 bits (327), Expect = 3e-30
 Identities = 78/218 (35%), Positives = 122/218 (55%), Gaps = 19/218 (8%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIA QG L +T   FW MIW+ +V +I+M T  +E+G+ KC++YWP  + +E    + 
Sbjct: 1382 KAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWP-ADGSEEYGNFL 1440

Query: 427  ILNEFESSTPDYTLRRFLV--TKKDETTVK-----RTIYHFHFTAWPDHRVPSEPGRVLN 479
            +  +       YT+R F +  TK  + + K     R +  +H+T WPD  VP     VL 
Sbjct: 1441 VTQKSIHVLAYYTIRNFTIRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYTLPVLT 1500

Query: 480  ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
             +   ++  +         A   V VHCSAG+GRTGT+IV+D +L QI+ EG    ++I 
Sbjct: 1501 FVRKASHAKRH--------AVGPVAVHCSAGVGRTGTYIVLDSMLQQIQHEG---TVNIF 1549

Query: 540  RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
              ++ +R QR+ +VQ E QY FI+ A++E I +++  V
Sbjct: 1550 GFLKHIRSQRNYLVQTEEQYVFIHDALVEAILSKETEV 1587



 Score = 68.5 bits (160), Expect = 5e-10
 Identities = 58/226 (25%), Positives = 97/226 (42%), Gaps = 27/226 (11%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK----K 424
            +I TQ  L  TI  FW MIW  + ++I+M        + +   YWP  NK E +     K
Sbjct: 1679 FIITQHPLLHTIKDFWRMIWDHNAQLIVMLPDSQNMAEDEFV-YWP--NKDEPINCESFK 1735

Query: 425  YTILNEFE---SSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
             T++ E     S+     ++ F++    +  V   + HF    WP+   P  P       
Sbjct: 1736 VTMIAEEHKCLSNEEKLIIQDFILEATQDDYVLE-VRHFQCPKWPN---PDSP------- 1784

Query: 482  LDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
            +   + L  I+          + VH   G    GTF  +  ++ Q+ KE     ID+++ 
Sbjct: 1785 ISKTFELISIIKDETSSRDGPMIVHDEHGGVTAGTFCALMTLMHQLEKEN---SIDVYQV 1841

Query: 542  VQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDS 587
             +M    R G+  +  QY+F+Y A+L  + T ++     P A+ DS
Sbjct: 1842 ARMTNLMRPGIFTDMEQYQFLYKAILSLVSTRQEE---NPSASLDS 1884



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 7/73 (9%)

Query: 201  GFWEEFETL-QMMENLQL------FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPD 253
            GF EEFETL +  + +Q             + P+N  KNRY NI+ +DH+RV L  +   
Sbjct: 1303 GFSEEFETLKEFYQEVQSCTVDLGITSDSSNHPDNKNKNRYINIVAYDHSRVKLTQLAEK 1362

Query: 254  GPPGSDYINANYI 266
                +DYINANY+
Sbjct: 1363 DGKMTDYINANYV 1375



 Score = 35.5 bits (78), Expect = 4.1
 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 4/63 (6%)

Query: 204  EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
            ++F+ L    N Q  D     K  N  KNR   IIP + +RV +  +  +   G+DYINA
Sbjct: 1612 KQFKLLSQT-NTQQCDYSTALKQCNREKNRTSAIIPVERSRVGISSLSGE---GTDYINA 1667

Query: 264  NYI 266
            +YI
Sbjct: 1668 SYI 1670


>UniRef50_Q7PWY3 Cluster: ENSANGP00000004166; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000004166 - Anopheles gambiae
           str. PEST
          Length = 684

 Score =  135 bits (326), Expect = 4e-30
 Identities = 72/207 (34%), Positives = 112/207 (54%), Gaps = 10/207 (4%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYW-PDLNKTEVVKKYTI 427
           YI+TQG L  T Y FW M+W++   +I+MTT+ +ERG+ KC +YW P          + +
Sbjct: 459 YISTQGPLPKTSYDFWRMVWEQHCLLIVMTTRVMERGRAKCGQYWEPTEGGLAEYGSFRL 518

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
                 +  DYT+   L  +  +T   R + H+ FT+WPD+ VPS    +LN L     +
Sbjct: 519 RTMSIETNEDYTVVE-LEIRNIKTDEVRCVSHWQFTSWPDYGVPSSAKAMLNFLQRAREK 577

Query: 488 LQQIMTG-----TDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
             +++          P    + VHCSAGIGRTGTFI +D+ + ++   G     DI  TV
Sbjct: 578 QAEMVRALGDLWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVG---TADIKGTV 634

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEF 569
           + +R QR+  +Q   QY F ++A++E+
Sbjct: 635 EKIRSQRAYSIQMPDQYVFCHLALIEY 661



 Score = 44.8 bits (101), Expect = 0.007
 Identities = 18/39 (46%), Positives = 28/39 (71%), Gaps = 2/39 (5%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N+ KNRY +++ +DH+RV+L     D  P +DYINAN++
Sbjct: 414 NLAKNRYTDVLCYDHSRVVLSQEEDD--PATDYINANFV 450


>UniRef50_UPI0000E4935D Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 967

 Score =  134 bits (325), Expect = 5e-30
 Identities = 72/216 (33%), Positives = 114/216 (52%), Gaps = 15/216 (6%)

Query: 368 TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI 427
           TY+A QG L  T+  FW M+W+ +  II+M   E E G+ KCERYW D  +        +
Sbjct: 104 TYLAAQGPLPHTVNEFWRMLWECNTEIIVMACNEFELGRHKCERYWVDEGEEHCFGDILV 163

Query: 428 LNEFESS-TPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
               +   T D+ +R    T+  E   ++    FH+TAWPDH VP+     +  +LD+  
Sbjct: 164 TQIGQQRVTKDFMIRTLKATRDKE---EKIFNQFHYTAWPDHGVPTS----VKPILDMIK 216

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
            +++  T  +PP    + VHCSAG GRTGT  VID + + ++ E  D    ++  +  +R
Sbjct: 217 LVREYQTAEEPP----IVVHCSAGCGRTGTICVIDYVRNALQLEKIDQNFSLYDIIVDMR 272

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPE 582
            QR  +VQ   QY+ ++ AV++  +     +G+ PE
Sbjct: 273 KQRHAIVQTRNQYELVHRAVVDMFQA---HLGIKPE 305



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 24/52 (46%), Positives = 36/52 (69%), Gaps = 2/52 (3%)

Query: 216 QLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           +++    G    N+RKNRYK+I+PFDH+R +L  I  D   GSDY+NAN+++
Sbjct: 48  KVYPTSAGESDVNMRKNRYKDILPFDHSRYLLSQI--DNVEGSDYVNANFLK 97


>UniRef50_UPI0000519EC5 Cluster: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 1
           (Protein-tyrosine phosphatase 1B) (PTP-1B)
           (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2)
           isoform 1; n=3; Endopterygota|Rep: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 1
           (Protein-tyrosine phosphatase 1B) (PTP-1B)
           (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2)
           isoform 1 - Apis mellifera
          Length = 495

 Score =  134 bits (325), Expect = 5e-30
 Identities = 79/209 (37%), Positives = 112/209 (53%), Gaps = 17/209 (8%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-------DLNKT 419
           + YI TQG L  T   FW MIW+++ + ++M  K IE+  VKC +YWP        +   
Sbjct: 92  RQYILTQGPLENTAGHFWLMIWEQNSKAVLMLNKIIEKNHVKCYQYWPLGESVINTMIFP 151

Query: 420 EVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLN 479
           +V  K   +++ ESS  DYT R   +T   ET   R I+HFH+T WPD  VP  P   LN
Sbjct: 152 DVGMKIKYISKTESS--DYTTRILKLTDL-ETKESREIFHFHYTTWPDFGVPQSPTAFLN 208

Query: 480 ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
            L DV  +   +     PP      VHCSAGIGR+GTF ++D  L  I + G +  ++I 
Sbjct: 209 FLTDVR-QSGTLDQNVGPPV-----VHCSAGIGRSGTFCLVDTCLVLIEENGLN-SVNIR 261

Query: 540 RTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
             +  +R  R G++Q   Q +F Y A++E
Sbjct: 262 DILIEMRRSRMGLIQTPDQLRFSYAAIIE 290



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 23/48 (47%), Positives = 33/48 (68%), Gaps = 6/48 (12%)

Query: 222 EGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           E  KP+N   NRY++++P+DH+R++LK     GP   DYINAN I+ D
Sbjct: 47  ESKKPQNKNLNRYRDVLPYDHSRIVLK----KGP--CDYINANLIQVD 88


>UniRef50_UPI00004D95F8 Cluster: protein tyrosine phosphatase,
            receptor type, H (PTPRH), mRNA; n=4; Xenopus
            tropicalis|Rep: protein tyrosine phosphatase, receptor
            type, H (PTPRH), mRNA - Xenopus tropicalis
          Length = 1249

 Score =  134 bits (325), Expect = 5e-30
 Identities = 77/207 (37%), Positives = 110/207 (53%), Gaps = 12/207 (5%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTE-VVKK 424
            +K +IA+QG L  T   FW MIW+  V  I+M T  +E G+VKCE YWP L+ T      
Sbjct: 1026 SKEFIASQGPLPNTSADFWRMIWENQVSTIVMLTNCMENGRVKCEHYWP-LDYTPCTYGD 1084

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
             T+    E   PD+T+R F + K  +    +   HFHFT WPDH VP     ++    ++
Sbjct: 1085 ITVTVTSEMILPDWTVRDFTL-KHAKQQGNKHARHFHFTVWPDHGVPENTTTIVE-FRNL 1142

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
                  +   + P       VHCSAG+GRTGT I +D ++ ++ KE     I I+  VQ 
Sbjct: 1143 VREYMDLKRSSGP-----TVVHCSAGVGRTGTLIALDYLIQKMEKEQ---RIGIYSFVQK 1194

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFIE 571
            +R  R  MVQ E+QY F+   +L+ I+
Sbjct: 1195 MRQNRPLMVQTESQYVFLNKCMLDLIQ 1221



 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 4/66 (6%)

Query: 201  GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
            GF EE++ L  +   Q   ++     EN  KNR+ N++P+DH+RV L  I  D    SDY
Sbjct: 959  GFAEEYQQLSNVGINQ--SKLAAELSENRSKNRFTNVLPYDHSRVRLNRI--DADETSDY 1014

Query: 261  INANYI 266
            INANY+
Sbjct: 1015 INANYM 1020


>UniRef50_Q4SQB7 Cluster: Chromosome 4 SCAF14533, whole genome shotgun
            sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 4
            SCAF14533, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2517

 Score =  134 bits (325), Expect = 5e-30
 Identities = 77/203 (37%), Positives = 107/203 (52%), Gaps = 14/203 (6%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-NKTEVVKK 424
            N  YIA QG L TT+  FW M+ ++   +I M T+E+E GKVKC+RYWPD     E+V  
Sbjct: 2317 NYMYIACQGPLPTTLSDFWQMVLEQKSNVIAMMTREVEGGKVKCQRYWPDTPMMPEMVDD 2376

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
               +   +    +    R +  K  +T   + + H ++T WPDH  P++P  +L     +
Sbjct: 2377 RLQITLIKDQFLENFGIRLIEVKDIQTNETQLVTHLNYTGWPDHGTPTQPEHLLTF---I 2433

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
            +Y      +G        V  HCSAGIGR+GT I ID +L  I K   D + DI   V+ 
Sbjct: 2434 SYMRHIHRSGP-------VITHCSAGIGRSGTLICIDTVLGLISK---DADFDISDVVRN 2483

Query: 545  VRDQRSGMVQNEAQYKFIYMAVL 567
            +R QR GMVQ E QY F Y  +L
Sbjct: 2484 MRLQRHGMVQTEDQYIFCYQVIL 2506



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 31/69 (44%), Positives = 41/69 (59%), Gaps = 9/69 (13%)

Query: 204  EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
            +EF+ LQ +E L   D +     EN +KNRYKN++PFD TRV+L      G  G  YINA
Sbjct: 2256 QEFDNLQNLEPLD--DCLIAQTKENKKKNRYKNVVPFDTTRVLL------GKDGG-YINA 2306

Query: 264  NYIRCDSMD 272
            N+I+    D
Sbjct: 2307 NFIKMSVKD 2315


>UniRef50_P43378 Cluster: Tyrosine-protein phosphatase non-receptor
           type 9; n=20; Euteleostomi|Rep: Tyrosine-protein
           phosphatase non-receptor type 9 - Homo sapiens (Human)
          Length = 593

 Score =  134 bits (325), Expect = 5e-30
 Identities = 75/212 (35%), Positives = 114/212 (53%), Gaps = 12/212 (5%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
           YI TQG L  T   FW M+W++ V +I+MTT+  E G+ KC +YWP    + +   +  +
Sbjct: 372 YIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTV 431

Query: 429 NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
                   ++  +  L     E   KR + HF F +WPD+ VPS    +++ L  V  R 
Sbjct: 432 TNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVV--RN 489

Query: 489 QQIMTGTDPPAQA-------VVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
           QQ +  ++  A++        + VHCSAGIGRTGTF  +D+ L Q+ + G    +++ +T
Sbjct: 490 QQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELG---TLNVFQT 546

Query: 542 VQMVRDQRSGMVQNEAQYKFIYMAVLEFIETE 573
           V  +R QR+  +Q   QY F Y A+LEF E E
Sbjct: 547 VSRMRTQRAFSIQTPEQYYFCYKAILEFAEKE 578



 Score = 40.3 bits (90), Expect = 0.14
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 10/91 (10%)

Query: 199 KQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGS 258
           KQG +EE+E ++    +  F       P N+ KNRY ++   D TRV  K     G   +
Sbjct: 300 KQGIYEEYEDIRRENPVGTFHC--SMSPGNLEKNRYGDVPCLDQTRV--KLTKRSGHTQT 355

Query: 259 DYINANYIRCDSMDSISDSQEFTG-NGSTEN 288
           DYINA++     MD       + G  G  EN
Sbjct: 356 DYINASF-----MDGYKQKNAYIGTQGPLEN 381


>UniRef50_UPI00005A2CD6 Cluster: PREDICTED: similar to Receptor-type
            tyrosine-protein phosphatase zeta precursor (R-PTP-zeta);
            n=1; Canis lupus familiaris|Rep: PREDICTED: similar to
            Receptor-type tyrosine-protein phosphatase zeta precursor
            (R-PTP-zeta) - Canis familiaris
          Length = 1926

 Score =  134 bits (324), Expect = 6e-30
 Identities = 78/218 (35%), Positives = 122/218 (55%), Gaps = 19/218 (8%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIA QG L +T   FW MIW+ +V +I+M T  +E+G+ KC++YWP  + +E    + 
Sbjct: 1346 KAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWP-ADGSEEYGNFL 1404

Query: 427  ILNEFESSTPDYTLRRFLV--TKKDETTVK-----RTIYHFHFTAWPDHRVPSEPGRVLN 479
            +  +       YT+R F +  TK  + + K     R +  +H+T WPD  VP     VL 
Sbjct: 1405 VTQKSVQMLAYYTVRSFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLPVLT 1464

Query: 480  ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
             +    +  +         A   V VHCSAG+GRTGT+IV+D +L QI++EG    ++I 
Sbjct: 1465 FVRKAAHAKRH--------AVGPVVVHCSAGVGRTGTYIVLDSMLQQIQQEG---TVNIF 1513

Query: 540  RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
              ++ +R QR+ +VQ E QY FI+ A++E I +++  V
Sbjct: 1514 GFLKHIRSQRNYLVQTEEQYVFIHDALVEAILSKETEV 1551



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 27/66 (40%), Positives = 36/66 (54%)

Query: 201  GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
            GF EEFE +Q             + P+N  KNRY NI+ +DH+RV L  +       +DY
Sbjct: 1274 GFTEEFEEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQLAEKDGKLTDY 1333

Query: 261  INANYI 266
            INANY+
Sbjct: 1334 INANYV 1339



 Score = 34.7 bits (76), Expect = 7.1
 Identities = 26/122 (21%), Positives = 53/122 (43%), Gaps = 15/122 (12%)

Query: 444  LVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVV 503
            L   KD+  ++  + HF    WP+   P  P       +   + L  I+          V
Sbjct: 1750 LALAKDDYVLE--VRHFQCPKWPN---PDSP-------ISKTFELISIIKEEAASRDGPV 1797

Query: 504  CVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIY 563
             VH   G    GTF  +  ++ Q+ KE     +D+++  +M+   R G+  + ++++ I+
Sbjct: 1798 VVHDEPGGVTAGTFCALTTLMHQLEKEN---SMDVYQVAKMINLMRPGVFADISKHRLIH 1854

Query: 564  MA 565
            ++
Sbjct: 1855 LS 1856


>UniRef50_A7T4C4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 322

 Score =  134 bits (324), Expect = 6e-30
 Identities = 75/191 (39%), Positives = 103/191 (53%), Gaps = 13/191 (6%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           + YIA+QG L  T+  FW ++WQE V  I+M T  +E GK KC RYWP         ++ 
Sbjct: 49  RAYIASQGPLPVTVADFWQLVWQEQVTTIVMLTNIVEVGKTKCHRYWPGGKARH--GEFD 106

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           I    E    DY +R F++ KKDE    R +  F +T+WPD  VP     VL       +
Sbjct: 107 ISLHREEVFADYVVRTFII-KKDEGQ-SRQVVQFQYTSWPDKGVPRHATSVL------GF 158

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
           R +     T    Q  + VHCSAG+GRTG FI ID +L++ +KE     +DIH  V ++R
Sbjct: 159 RRKVRAHYTSRNGQVPMLVHCSAGVGRTGAFIAIDAMLERAKKEK---TVDIHNYVNVMR 215

Query: 547 DQRSGMVQNEA 557
           + R  M+Q EA
Sbjct: 216 NNRCTMIQTEA 226


>UniRef50_P54829 Cluster: Tyrosine-protein phosphatase non-receptor
           type 5; n=27; Euteleostomi|Rep: Tyrosine-protein
           phosphatase non-receptor type 5 - Homo sapiens (Human)
          Length = 541

 Score =  134 bits (324), Expect = 6e-30
 Identities = 81/216 (37%), Positives = 116/216 (53%), Gaps = 17/216 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           K YIATQG + +T+  FW M+WQE   II+M T  IE    KC  YWP+        + T
Sbjct: 343 KVYIATQGPIVSTVADFWRMVWQEHTPIIVMIT-NIEEMNEKCTEYWPEEQVAYDGVEIT 401

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           +       T DY LR  L++ K  T  +R + H+ FT+WPD + P     +L+++ +V  
Sbjct: 402 VQKVIH--TEDYRLR--LISLKSGTE-ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE 456

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
             QQ     + P  A + VHCSAGIGRTG FI   +   Q+R+EG    +DI +T   +R
Sbjct: 457 AAQQ-----EGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGV---VDILKTTCQLR 508

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPE 582
             R GM+Q+  QY+F++  +  +   EKQ     PE
Sbjct: 509 QDRGGMIQHCEQYQFVHHVMSLY---EKQLSHQSPE 541



 Score = 50.0 bits (114), Expect = 2e-04
 Identities = 25/42 (59%), Positives = 27/42 (64%), Gaps = 1/42 (2%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           P   RKNRYK I+P  H+RV L    PD P  S YINANYIR
Sbjct: 296 PGRCRKNRYKTILPNPHSRVCLTSPDPDDPL-SSYINANYIR 336


>UniRef50_UPI0000E4A291 Cluster: PREDICTED: similar to
           testis-enriched protein tyrosine phosphatase; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           testis-enriched protein tyrosine phosphatase -
           Strongylocentrotus purpuratus
          Length = 659

 Score =  134 bits (323), Expect = 8e-30
 Identities = 75/210 (35%), Positives = 111/210 (52%), Gaps = 14/210 (6%)

Query: 359 VPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-N 417
           +P   + NK Y+A QG L  T+  FW M+W++   +I+M T  +ERG+VKC +YWPDL +
Sbjct: 447 IPGFDLVNK-YVAAQGPLPNTVNDFWYMVWEQRSTLIVMLTTNVERGRVKCHKYWPDLDD 505

Query: 418 KTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRV 477
           + +      +       TP +  R F++     T  +R +    + AWPDH VP +    
Sbjct: 506 RLKFGPDLEVRCTRCDETPSFAYRDFIIC-NTATKEERIVLQMQYVAWPDHGVPDDSSDF 564

Query: 478 LNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEID 537
           L+ +L    R++Q   G D P      VHCSAGIGRTG  I ++  +  I        +D
Sbjct: 565 LDFVL----RVRQCRVGMDVP----TIVHCSAGIGRTGVLITMETAMCLIEANEPVYPLD 616

Query: 538 IHRTVQMVRDQRSGMVQNEAQYKFIYMAVL 567
           I RT    RDQR  ++Q  AQYKF+  A++
Sbjct: 617 IVRT---ERDQRPMLIQTAAQYKFVCEAII 643



 Score = 44.4 bits (100), Expect = 0.009
 Identities = 22/43 (51%), Positives = 28/43 (65%), Gaps = 5/43 (11%)

Query: 227 ENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           EN+ KNRY++I P+D TRVIL++         DYINAN I  D
Sbjct: 409 ENVAKNRYRDIAPYDATRVILREADT-----GDYINANTINMD 446


>UniRef50_UPI0000E494F1 Cluster: PREDICTED: similar to
            protein-tyrosine phosphatase; n=1; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to protein-tyrosine
            phosphatase - Strongylocentrotus purpuratus
          Length = 1024

 Score =  134 bits (323), Expect = 8e-30
 Identities = 69/224 (30%), Positives = 118/224 (52%), Gaps = 11/224 (4%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YIATQG +S T++ FW M+W+++   I+M  + IE GK KC++YWP  +   V  K  + 
Sbjct: 801  YIATQGPMSNTVHEFWRMVWEKECPAIVMLVRCIEGGKEKCDKYWPINSDPTVFGKVIVT 860

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
               E +   + +R F +    E   +R I  +HF +WP H  P      LN + ++   L
Sbjct: 861  KLAEHTHDTWAVRDFRLKVGSE---ERLIRQYHFISWPTHSTPRVSRPTLNFVKNIREEL 917

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            +       P     + VHC AGIGRTG FI +D++L +++ +  +  +D+   V  +R +
Sbjct: 918  E------SPKLSGPLVVHCGAGIGRTGVFIALDILLQELKAD--ERTVDVFAVVAKMRRE 969

Query: 549  RSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDSPRARS 592
            R  +VQ+  QY F++ A+ +F++ +   V +      D+   +S
Sbjct: 970  RCSLVQSLVQYIFLHRALADFLQGQGHGVEVSSIERSDAGSIQS 1013


>UniRef50_UPI000065CBFD Cluster: Tyrosine-protein phosphatase
           non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine
           phosphatase MEG2) (PTPase-MEG2).; n=1; Takifugu
           rubripes|Rep: Tyrosine-protein phosphatase non-receptor
           type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2)
           (PTPase-MEG2). - Takifugu rubripes
          Length = 617

 Score =  134 bits (323), Expect = 8e-30
 Identities = 72/215 (33%), Positives = 116/215 (53%), Gaps = 10/215 (4%)

Query: 365 YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVK 423
           +   YI TQG L  T   FW M+W+++V +I+MTT+  E  + KC +YWP +    EV  
Sbjct: 404 HRNAYIGTQGPLENTYGDFWRMVWEQNVLVIVMTTRTNEGNRRKCGQYWPLEEGGQEVYG 463

Query: 424 KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
              ++N+       Y     LV    ET  +R + HF + +WPD+ VP+    +++ L  
Sbjct: 464 HMAVVNQRVDHHTHYN-HTTLVLHNTETCEQRQVSHFQYLSWPDYGVPTSAVTLIDFLGA 522

Query: 484 VNYRLQQIMTGTDP-----PAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
           V  + ++++    P     P    + VHCSAGIGRTGTF  +D+ L Q++  G    +++
Sbjct: 523 VKRQQRKMVNTLGPQWTGHPQGPPMVVHCSAGIGRTGTFCALDICLSQLQDVG---SLNV 579

Query: 539 HRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETE 573
            +TV+ +R QR+  +Q   QY F Y A+LE  + +
Sbjct: 580 CQTVRRMRTQRAFSIQTPDQYYFCYNAILEHAQRQ 614


>UniRef50_P23471-2 Cluster: Isoform Short of P23471 ; n=6;
            Tetrapoda|Rep: Isoform Short of P23471 - Homo sapiens
            (Human)
          Length = 1454

 Score =  134 bits (323), Expect = 8e-30
 Identities = 78/218 (35%), Positives = 120/218 (55%), Gaps = 19/218 (8%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIA QG L +T   FW MIW+ +V +I+M T  +E+G+ KC++YWP  + +E    + 
Sbjct: 934  KAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWP-ADGSEEYGNFL 992

Query: 427  ILNEFESSTPDYTLRRFLV--TKKDETTVK-----RTIYHFHFTAWPDHRVPSEPGRVLN 479
            +  +       YT+R F +  TK  + + K     R +  +H+T WPD  VP     VL 
Sbjct: 993  VTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLPVLT 1052

Query: 480  ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
             +    Y  +         A   V VHCSAG+GRTGT+IV+D +L QI+ EG    ++I 
Sbjct: 1053 FVRKAAYAKRH--------AVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEG---TVNIF 1101

Query: 540  RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
              ++ +R QR+ +VQ E QY FI+  ++E I +++  V
Sbjct: 1102 GFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEV 1139



 Score = 64.9 bits (151), Expect = 6e-09
 Identities = 56/226 (24%), Positives = 99/226 (43%), Gaps = 27/226 (11%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK----K 424
            +I TQ  L  TI  FW MIW  + ++++M        + +   YWP  NK E +     K
Sbjct: 1231 FIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFV-YWP--NKDEPINCESFK 1287

Query: 425  YTILNEFE---SSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
             T++ E     S+     ++ F++    +  V   + HF    WP+   P  P      L
Sbjct: 1288 VTLMAEEHKCLSNEEKLIIQDFILEATQDDYVLE-VRHFQCPKWPN---PDSPISKTFEL 1343

Query: 482  LDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
            + V   +++     D P    + VH   G    GTF  +  ++ Q+ KE     +D+++ 
Sbjct: 1344 ISV---IKEEAANRDGP----MIVHDEHGGVTAGTFCALTTLMHQLEKEN---SVDVYQV 1393

Query: 542  VQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDS 587
             +M+   R G+  +  QY+F+Y  +L  + T ++     P  + DS
Sbjct: 1394 AKMINLMRPGVFADIEQYQFLYKVILSLVSTRQEE---NPSTSLDS 1436



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 7/73 (9%)

Query: 201 GFWEEFETL-QMMENLQL------FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPD 253
           GF EEFETL +  + +Q             + P+N  KNRY NI+ +DH+RV L  +   
Sbjct: 855 GFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQLAEK 914

Query: 254 GPPGSDYINANYI 266
               +DYINANY+
Sbjct: 915 DGKLTDYINANYV 927



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 4/74 (5%)

Query: 193  IESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPP 252
            I   A K    ++F+ L    N+Q  D     K  N  KNR  +IIP + +RV +  +  
Sbjct: 1153 IPGPAGKTKLEKQFQLLSQ-SNIQQSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSG 1211

Query: 253  DGPPGSDYINANYI 266
            +   G+DYINA+YI
Sbjct: 1212 E---GTDYINASYI 1222


>UniRef50_P23471 Cluster: Receptor-type tyrosine-protein phosphatase
            zeta precursor; n=10; Euarchontoglires|Rep: Receptor-type
            tyrosine-protein phosphatase zeta precursor - Homo
            sapiens (Human)
          Length = 2314

 Score =  134 bits (323), Expect = 8e-30
 Identities = 78/218 (35%), Positives = 120/218 (55%), Gaps = 19/218 (8%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIA QG L +T   FW MIW+ +V +I+M T  +E+G+ KC++YWP  + +E    + 
Sbjct: 1794 KAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWP-ADGSEEYGNFL 1852

Query: 427  ILNEFESSTPDYTLRRFLV--TKKDETTVK-----RTIYHFHFTAWPDHRVPSEPGRVLN 479
            +  +       YT+R F +  TK  + + K     R +  +H+T WPD  VP     VL 
Sbjct: 1853 VTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPSGRVVTQYHYTQWPDMGVPEYSLPVLT 1912

Query: 480  ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
             +    Y  +         A   V VHCSAG+GRTGT+IV+D +L QI+ EG    ++I 
Sbjct: 1913 FVRKAAYAKRH--------AVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEG---TVNIF 1961

Query: 540  RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
              ++ +R QR+ +VQ E QY FI+  ++E I +++  V
Sbjct: 1962 GFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEV 1999



 Score = 64.9 bits (151), Expect = 6e-09
 Identities = 56/226 (24%), Positives = 99/226 (43%), Gaps = 27/226 (11%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK----K 424
            +I TQ  L  TI  FW MIW  + ++++M        + +   YWP  NK E +     K
Sbjct: 2091 FIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFV-YWP--NKDEPINCESFK 2147

Query: 425  YTILNEFE---SSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
             T++ E     S+     ++ F++    +  V   + HF    WP+   P  P      L
Sbjct: 2148 VTLMAEEHKCLSNEEKLIIQDFILEATQDDYVLE-VRHFQCPKWPN---PDSPISKTFEL 2203

Query: 482  LDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
            + V   +++     D P    + VH   G    GTF  +  ++ Q+ KE     +D+++ 
Sbjct: 2204 ISV---IKEEAANRDGP----MIVHDEHGGVTAGTFCALTTLMHQLEKEN---SVDVYQV 2253

Query: 542  VQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDS 587
             +M+   R G+  +  QY+F+Y  +L  + T ++     P  + DS
Sbjct: 2254 AKMINLMRPGVFADIEQYQFLYKVILSLVSTRQEE---NPSTSLDS 2296



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 29/73 (39%), Positives = 40/73 (54%), Gaps = 7/73 (9%)

Query: 201  GFWEEFETL-QMMENLQL------FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPD 253
            GF EEFETL +  + +Q             + P+N  KNRY NI+ +DH+RV L  +   
Sbjct: 1715 GFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQLAEK 1774

Query: 254  GPPGSDYINANYI 266
                +DYINANY+
Sbjct: 1775 DGKLTDYINANYV 1787



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 4/74 (5%)

Query: 193  IESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPP 252
            I   A K    ++F+ L    N+Q  D     K  N  KNR  +IIP + +RV +  +  
Sbjct: 2013 IPGPAGKTKLEKQFQLLSQ-SNIQQSDYSAALKQCNREKNRTSSIIPVERSRVGISSLSG 2071

Query: 253  DGPPGSDYINANYI 266
            +   G+DYINA+YI
Sbjct: 2072 E---GTDYINASYI 2082


>UniRef50_O55082 Cluster: Tyrosine-protein phosphatase non-receptor
           type 20; n=8; Eutheria|Rep: Tyrosine-protein phosphatase
           non-receptor type 20 - Mus musculus (Mouse)
          Length = 426

 Score =  134 bits (323), Expect = 8e-30
 Identities = 76/204 (37%), Positives = 108/204 (52%), Gaps = 15/204 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
           YIATQG L  TI  FW M+ + +  +I M T+EIE G +KC  YWP  L +    + +++
Sbjct: 231 YIATQGPLPETIEDFWQMVLENNCNVIAMITREIECGVIKCYSYWPISLKEPLEFEHFSV 290

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
             E    T  +T+R F + KK  T   + + H  FT WPDH  P+     +     V Y 
Sbjct: 291 FLETFHVTQYFTVRVFQIVKK-STGKSQCVKHLQFTKWPDHGTPASADFFIKY---VRYV 346

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
            +  +TG        + VHCSAG+GRTG FI +D++   I K   +   DI   V  +R 
Sbjct: 347 RKSHITGP-------LLVHCSAGVGRTGVFICVDVVFSAIEK---NYSFDIMNIVTQMRK 396

Query: 548 QRSGMVQNEAQYKFIYMAVLEFIE 571
           QR GM+Q + QY+F Y  VLE ++
Sbjct: 397 QRCGMIQTKEQYQFCYEIVLEVLQ 420



 Score = 39.5 bits (88), Expect = 0.25
 Identities = 23/49 (46%), Positives = 30/49 (61%), Gaps = 7/49 (14%)

Query: 219 DRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           D   G+  +N  KNRY++I+P+D TRV      P G    DYINA+YIR
Sbjct: 180 DFNSGNTLQNRDKNRYRDILPYDSTRV------PLG-KNKDYINASYIR 221


>UniRef50_Q8MY44 Cluster: CD45; n=5; Eptatretus stoutii|Rep: CD45 -
           Eptatretus stoutii (Pacific hagfish)
          Length = 1222

 Score =  133 bits (322), Expect = 1e-29
 Identities = 77/204 (37%), Positives = 107/204 (52%), Gaps = 15/204 (7%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKK 424
           +K YI  QG +  T   FW+MIW++   +IIM T+ IE GK KC +YWP    K    K 
Sbjct: 662 SKKYICAQGPMEETAAEFWTMIWEQKTAVIIMVTRCIEGGKNKCYQYWPRQKGKKLEFKS 721

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
            ++ N      PDY +    +     +   R I H  FT WPDH VP +P    ++LL +
Sbjct: 722 LSVTNNEVMLYPDYIITEISLNHGGNS---RIITHVQFTKWPDHGVPDDP----DLLLRL 774

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
             R+       D P    + VHCSAG+GR+GTFI I  +++ +  EG    ID++  V  
Sbjct: 775 RRRVLSFCNFFDGP----MVVHCSAGVGRSGTFIAISSLMEMLEDEG---RIDVYGFVVS 827

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLE 568
           +R QR  MVQ E QY  I+  +LE
Sbjct: 828 LRQQRCLMVQVEDQYILIHQVLLE 851



 Score =  110 bits (265), Expect = 9e-23
 Identities = 67/206 (32%), Positives = 108/206 (52%), Gaps = 12/206 (5%)

Query: 368  TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI 427
            T+IATQG L  T+  FW M++Q+D   I+M T+  E G  +C +YWP+ +     +    
Sbjct: 965  TFIATQGPLQNTLAHFWHMVFQKDCHNIVMLTELTEGGVEQCYQYWPEKDAQTYGEVEVQ 1024

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            L E E    + T+RRF +  K +    R +  F   +W    VPS    ++ I+  +  +
Sbjct: 1025 LVETEKPNEELTVRRFNIKHKQKC---REVRQFQIHSWRGKVVPSSNKGLIEIIKTI--Q 1079

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
            ++Q + G   P    + VHCS G  RTGTF  +  IL+  R EG    +D+ +TV+ +R 
Sbjct: 1080 MKQEIFGFKRP----IVVHCSDGAERTGTFCALWNILESGRMEGM---VDVFQTVKKLRL 1132

Query: 548  QRSGMVQNEAQYKFIYMAVLEFIETE 573
            QR  M++    Y+F Y  V++ I+ +
Sbjct: 1133 QRPAMIKTLDHYRFCYETVVKVIKVQ 1158



 Score = 52.8 bits (121), Expect = 3e-05
 Identities = 28/65 (43%), Positives = 39/65 (60%), Gaps = 4/65 (6%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F +EFE++  +         E  +P N  KNRY +I+P+D+ RV L  +   G PGSDYI
Sbjct: 596 FQQEFESIPRVWKSN--PSKEAQQPHNNGKNRYSDILPYDNNRVRL--VSNGGKPGSDYI 651

Query: 262 NANYI 266
           NA+YI
Sbjct: 652 NASYI 656


>UniRef50_P35992 Cluster: Tyrosine-protein phosphatase 10D precursor;
            n=11; Endopterygota|Rep: Tyrosine-protein phosphatase 10D
            precursor - Drosophila melanogaster (Fruit fly)
          Length = 1631

 Score =  133 bits (322), Expect = 1e-29
 Identities = 84/226 (37%), Positives = 122/226 (53%), Gaps = 23/226 (10%)

Query: 357  NGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL 416
            N VP  H   + +I TQG L +T   FW M W+ + R I+M T+  E+G+ KC++YWP  
Sbjct: 1330 NYVPG-HNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP-- 1386

Query: 417  NKTEVV----KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPS 472
            N T  V     K  ILN  +S   D+ +  F++ +  E   +R + HFHFT WPD  VP+
Sbjct: 1387 NDTVPVFYGDIKVQILN--DSHYADWVMTEFMLCRGSE---QRILRHFHFTTWPDFGVPN 1441

Query: 473  EPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGF 532
             P  ++  +     R+     G +   Q  + VHCSAG+GR+GTFI +D IL QI    +
Sbjct: 1442 PPQTLVRFVRAFRDRI-----GAE---QRPIVVHCSAGVGRSGTFITLDRILQQINTSDY 1493

Query: 533  DCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVG 578
               +DI   V  +R +R  MVQ E QY  I+  +L  +E ++  VG
Sbjct: 1494 ---VDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLEGKENIVG 1536



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 30/65 (46%), Positives = 39/65 (60%), Gaps = 4/65 (6%)

Query: 202  FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
            F EEFE L+ +   Q     +   P N  KNR+ NI+P+DH+R  L+  P D   GSDYI
Sbjct: 1272 FSEEFEELKHVGRDQPCTFAD--LPCNRPKNRFTNILPYDHSRFKLQ--PVDDDEGSDYI 1327

Query: 262  NANYI 266
            NANY+
Sbjct: 1328 NANYV 1332


>UniRef50_A0AV39 Cluster: Protein tyrosine phosphatase, receptor type,
            O; n=16; Euteleostomi|Rep: Protein tyrosine phosphatase,
            receptor type, O - Homo sapiens (Human)
          Length = 1216

 Score =  133 bits (321), Expect = 1e-29
 Identities = 77/208 (37%), Positives = 109/208 (52%), Gaps = 12/208 (5%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YIATQG L  T   FW M+ Q+  +II+M T+  E+ +VKC+ YWP   +       T+ 
Sbjct: 1007 YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVE 1066

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
               E    D+  R F +   DE    + + HF++TAWPDH VP+        +L   + +
Sbjct: 1067 MISEEEQDDWACRHFRINYADE---MQDVMHFNYTAWPDHGVPT--ANAAESILQFVHMV 1121

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            +Q  T +  P    + +HCSAG+GRTGTFI +D +L  IR   F   +DI   V  +R  
Sbjct: 1122 RQQATKSKGP----MIIHCSAGVGRTGTFIALDRLLQHIRDHEF---VDILGLVSEMRSY 1174

Query: 549  RSGMVQNEAQYKFIYMAVLEFIETEKQR 576
            R  MVQ E QY FI+  V      +KQ+
Sbjct: 1175 RMSMVQTEEQYIFIHQCVQLMWMKKKQQ 1202



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 13/94 (13%)

Query: 173 IQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKN 232
           +Q+  F   +K + K+++       YK  F  +FE L+++  L +        P N  KN
Sbjct: 918 VQLDDFDAYIKDMAKDSD-------YK--FSLQFEELKLI-GLDI-PHFAADLPLNRCKN 966

Query: 233 RYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           RY NI+P+D +RV L  +  +   G+DYINANYI
Sbjct: 967 RYTNILPYDFSRVRL--VSMNEEEGADYINANYI 998


>UniRef50_Q16827 Cluster: Receptor-type tyrosine-protein phosphatase O
            precursor; n=30; Euteleostomi|Rep: Receptor-type
            tyrosine-protein phosphatase O precursor - Homo sapiens
            (Human)
          Length = 1216

 Score =  133 bits (321), Expect = 1e-29
 Identities = 77/208 (37%), Positives = 109/208 (52%), Gaps = 12/208 (5%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YIATQG L  T   FW M+ Q+  +II+M T+  E+ +VKC+ YWP   +       T+ 
Sbjct: 1007 YIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVE 1066

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
               E    D+  R F +   DE    + + HF++TAWPDH VP+        +L   + +
Sbjct: 1067 MISEEEQDDWACRHFRINYADE---MQDVMHFNYTAWPDHGVPT--ANAAESILQFVHMV 1121

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            +Q  T +  P    + +HCSAG+GRTGTFI +D +L  IR   F   +DI   V  +R  
Sbjct: 1122 RQQATKSKGP----MIIHCSAGVGRTGTFIALDRLLQHIRDHEF---VDILGLVSEMRSY 1174

Query: 549  RSGMVQNEAQYKFIYMAVLEFIETEKQR 576
            R  MVQ E QY FI+  V      +KQ+
Sbjct: 1175 RMSMVQTEEQYIFIHQCVQLMWMKKKQQ 1202



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 13/94 (13%)

Query: 173 IQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKN 232
           +Q+  F   +K + K+++       YK  F  +FE L+++  L +        P N  KN
Sbjct: 918 VQLDDFDAYIKDMAKDSD-------YK--FSLQFEELKLI-GLDI-PHFAADLPLNRCKN 966

Query: 233 RYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           RY NI+P+D +RV L  +  +   G+DYINANYI
Sbjct: 967 RYTNILPYDFSRVRL--VSMNEEEGADYINANYI 998


>UniRef50_P35821 Cluster: Tyrosine-protein phosphatase non-receptor
           type 1; n=16; Amniota|Rep: Tyrosine-protein phosphatase
           non-receptor type 1 - Mus musculus (Mouse)
          Length = 432

 Score =  133 bits (321), Expect = 1e-29
 Identities = 75/207 (36%), Positives = 111/207 (53%), Gaps = 14/207 (6%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV---- 422
           ++YI TQG L  T   FW M+W++  R ++M  + +E+G +KC +YWP   + E+V    
Sbjct: 79  RSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQQEEKEMVFDDT 138

Query: 423 -KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
             K T+++E   S   YT+R+ L  +   T   R I HFH+T WPD  VP  P   LN L
Sbjct: 139 GLKLTLISEDVKSY--YTVRQ-LELENLTTKETREILHFHYTTWPDFGVPESPASFLNFL 195

Query: 482 LDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
             V        +G+       + VHCSAGIGR+GTF + D  L  + K      +DI + 
Sbjct: 196 FKVR------ESGSLSLEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKV 249

Query: 542 VQMVRDQRSGMVQNEAQYKFIYMAVLE 568
           +  +R  R G++Q   Q +F Y+AV+E
Sbjct: 250 LLEMRRFRMGLIQTADQLRFSYLAVIE 276



 Score = 37.5 bits (83), Expect = 1.0
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 6/44 (13%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           P+N  +NRY+++ PFDH+R+ L          +DYINA+ I+ +
Sbjct: 38  PKNKNRNRYRDVSPFDHSRIKLHQ------EDNDYINASLIKME 75


>UniRef50_O01556 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 374

 Score =  132 bits (320), Expect = 2e-29
 Identities = 82/221 (37%), Positives = 124/221 (56%), Gaps = 21/221 (9%)

Query: 362 VHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL---NK 418
           + +  K +I TQG   +TIY FW+M+ Q++V  IIM  K IE  +VKCE+YWP +     
Sbjct: 126 ISIKPKKFICTQGPKDSTIYDFWAMVIQDNVESIIMLCKVIELARVKCEQYWPAVEGQTN 185

Query: 419 TEVVKKYTI-LNEFESST--PDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPG 475
           T V K +TI +N     T  PD         +       R+I H+ +T WPDH  P    
Sbjct: 186 TYVSKGHTITINNLGVGTLSPDDDFINVTNLELVWAGKTRSITHYQWTNWPDHGAPPINM 245

Query: 476 RVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCE 535
             +N++  VNY        T+P     V VHCSAG+GR+GT + I +I+D++  +G +C+
Sbjct: 246 GAINLIEAVNY-------DTNP-----VVVHCSAGVGRSGTIVGISLIMDKM-IQGINCK 292

Query: 536 IDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE-FIETEKQ 575
            D+ + V+ +R+QR   +Q EAQY +I+  +LE F+E  K+
Sbjct: 293 -DMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKE 332


>UniRef50_Q5W0Y5 Cluster: Protein tyrosine phosphatase, receptor type,
            T; n=17; Euteleostomi|Rep: Protein tyrosine phosphatase,
            receptor type, T - Homo sapiens (Human)
          Length = 1451

 Score =  132 bits (320), Expect = 2e-29
 Identities = 84/220 (38%), Positives = 109/220 (49%), Gaps = 34/220 (15%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGK--------------------VK 408
            YIATQG +  T+  FW MIWQE+   I+M T  +E G+                    VK
Sbjct: 947  YIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGNATLGRAASPGMVK 1006

Query: 409  CERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDH 468
            C RYWPD   TEV     +         +Y +R F V KK    + R +  FHFT+WPDH
Sbjct: 1007 CVRYWPD--DTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEI-RELRLFHFTSWPDH 1063

Query: 469  RVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIR 528
             VP     +L  +  V +         +PP    + VHCSAG GRTG FI ID +LD   
Sbjct: 1064 GVPCYATGLLGFVRQVKF--------LNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAE 1115

Query: 529  KEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
             EG    +DI   V+ +R QR  +VQ E QY F++ A+LE
Sbjct: 1116 NEGV---VDIFNCVRELRAQRVNLVQTEEQYVFVHDAILE 1152



 Score = 76.6 bits (180), Expect = 2e-12
 Identities = 60/213 (28%), Positives = 100/213 (46%), Gaps = 15/213 (7%)

Query: 363  HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
            H     ++ TQ  L  T+  FW +++  +   ++M   E++  +  C +YWP+  KT   
Sbjct: 1250 HKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLN-EMDTAQF-CMQYWPE--KTSGC 1305

Query: 423  KKYTILNEFESSTPDYTL--RRFLVTKKDETTVK-RTIYHFHFTAWPDHRVPSEPGRVLN 479
                I  EF S+  D  +  R F +          R + H  +  WP +R  + P +   
Sbjct: 1306 YG-PIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYR-DTPPSK--R 1361

Query: 480  ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
             LL V  RL++     D      V VHC  G GR+GTF  I  + + I+++     ID+ 
Sbjct: 1362 SLLKVVRRLEKWQEQYDGREGRTV-VHCLNGGGRSGTFCAICSVCEMIQQQNI---IDVF 1417

Query: 540  RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
              V+ +R+ +S MV+   QYKF+Y   LE++ +
Sbjct: 1418 HIVKTLRNNKSNMVETLEQYKFVYEVALEYLSS 1450



 Score = 54.8 bits (126), Expect = 6e-06
 Identities = 33/66 (50%), Positives = 41/66 (62%), Gaps = 5/66 (7%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF EE+E L   +    +D  +  + EN  KNRY NII +DH+RV L  +  DG P SDY
Sbjct: 878 GFKEEYEALPEGQTAS-WDTAK--EDENRNKNRYGNIISYDHSRVRL--LVLDGDPHSDY 932

Query: 261 INANYI 266
           INANYI
Sbjct: 933 INANYI 938


>UniRef50_Q92932 Cluster: Receptor-type tyrosine-protein phosphatase
            N2 precursor; n=36; Gnathostomata|Rep: Receptor-type
            tyrosine-protein phosphatase N2 precursor - Homo sapiens
            (Human)
          Length = 1015

 Score =  132 bits (320), Expect = 2e-29
 Identities = 76/204 (37%), Positives = 111/204 (54%), Gaps = 13/204 (6%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKK 424
            N  YIATQG L  T+  FW M+W+    +I+M T   E G  +C  YWPD       + +
Sbjct: 813  NPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYE 872

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
              +++E      D+ +R F + K  +T   RT+  FHF +W D  VPS        LLD 
Sbjct: 873  VNLVSE-HIWCEDFLVRSFYL-KNLQTNETRTVTQFHFLSWYDRGVPSSS----RSLLDF 926

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
              ++ +   G   P    + VHCS G GR+GT+++IDM+L+++ K     EIDI  T++ 
Sbjct: 927  RRKVNKCYRGRSCP----IIVHCSDGAGRSGTYVLIDMVLNKMAKGA--KEIDIAATLEH 980

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLE 568
            +RDQR GMVQ + Q++F   AV E
Sbjct: 981  LRDQRPGMVQTKEQFEFALTAVAE 1004



 Score = 35.9 bits (79), Expect = 3.1
 Identities = 18/42 (42%), Positives = 27/42 (64%), Gaps = 2/42 (4%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           + EN+ KNR   ++ +DH+RV+LK    +    SDYINA+ I
Sbjct: 767 REENVPKNRSLAVLTYDHSRVLLK--AENSHSHSDYINASPI 806


>UniRef50_Q4JDL3 Cluster: Tyrosine-protein phosphatase non-receptor
           type 20; n=32; Catarrhini|Rep: Tyrosine-protein
           phosphatase non-receptor type 20 - Homo sapiens (Human)
          Length = 420

 Score =  132 bits (320), Expect = 2e-29
 Identities = 76/203 (37%), Positives = 107/203 (52%), Gaps = 15/203 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
           YIATQG L +TI  FW M+ + +  +I M T+EIE G +KC  YWP  L K   +K + +
Sbjct: 225 YIATQGPLLSTIDDFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKHFRV 284

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
             E       + +R F V +K  T    ++    FT WPDH  P+     +     + Y 
Sbjct: 285 FLENYQILQYFIIRMFQVVEK-STGTSHSVKQLQFTKWPDHGTPASADSFIKY---IRYA 340

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
            +  +TG        + VHCSAGIGRTG F+ +D++   I K   +C  +I   V  +R+
Sbjct: 341 RKSHLTGP-------MVVHCSAGIGRTGVFLCVDVVFCAIVK---NCSFNIMDIVAQMRE 390

Query: 548 QRSGMVQNEAQYKFIYMAVLEFI 570
           QRSGMVQ + QY F Y  VLE +
Sbjct: 391 QRSGMVQTKEQYHFCYDIVLEVL 413



 Score = 44.4 bits (100), Expect = 0.009
 Identities = 27/64 (42%), Positives = 38/64 (59%), Gaps = 9/64 (14%)

Query: 204 EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
           +EF  L++      F+   G++P N  KNRY++I+P+D TRV      P G    DYINA
Sbjct: 161 QEFMALELKNLPGEFN--SGNQPSNREKNRYRDILPYDSTRV------PLG-KSKDYINA 211

Query: 264 NYIR 267
           +YIR
Sbjct: 212 SYIR 215


>UniRef50_UPI0000E8189A Cluster: PREDICTED: similar to human
           phosphotyrosine phosphatase kappa; n=2; Gallus
           gallus|Rep: PREDICTED: similar to human phosphotyrosine
           phosphatase kappa - Gallus gallus
          Length = 857

 Score =  132 bits (319), Expect = 3e-29
 Identities = 80/220 (36%), Positives = 119/220 (54%), Gaps = 28/220 (12%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI- 427
           +IA QG L  T+  FW M+WQE + +I+M T  +E+ KVKCE+YWP+  + +V   +T+ 
Sbjct: 454 FIAAQGPLPGTVVDFWQMVWQEKISVIVMLTGLVEQNKVKCEQYWPE--QQQVYGDFTVT 511

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
           LN   ++T    + R    +K    + + +  FH+  WPDH VP  P ++L ++  VN  
Sbjct: 512 LNNTRTTTG--LITRVFCLQKAGCVLPKVVEQFHYLQWPDHDVPRNPAQLLCLVEMVNKS 569

Query: 488 LQQIMTGT--------DPPA-----------QAVVCVHCSAGIGRTGTFIVIDMILDQIR 528
             +  TG         D  A           Q + CV  SAGIGRTGTFI +D +L   +
Sbjct: 570 GSESPTGPVLVHCRYWDGSALVLEQGWPGLYQPLSCV-LSAGIGRTGTFIALDFLLKMAK 628

Query: 529 KEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
            EG   ++D+   VQ +R+QR  MVQ + QY F+Y  +LE
Sbjct: 629 AEG---KVDVFHCVQKLREQRICMVQTKEQYAFLYEVLLE 665



 Score = 40.7 bits (91), Expect = 0.11
 Identities = 18/70 (25%), Positives = 37/70 (52%), Gaps = 3/70 (4%)

Query: 503 VCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFI 562
           + V C  G  R+G F     + +QI+ EG    +D+ + V+M++ +R  ++++  QY   
Sbjct: 783 ILVTCWDGASRSGIFCAASFLCEQIQSEGL---VDVSQAVRMLKRRRRQLIKDVEQYGLC 839

Query: 563 YMAVLEFIET 572
           Y   L ++ +
Sbjct: 840 YKLALSYLNS 849



 Score = 38.7 bits (86), Expect = 0.44
 Identities = 24/62 (38%), Positives = 32/62 (51%), Gaps = 4/62 (6%)

Query: 204 EEFETLQMMENL-QLFDRMEGSKPENIRKNRYKNIIPFDHTR-VILKDIPPDGPPGSDYI 261
           +EF+ +Q    L QL    E  KP N  KNR   I+P D  R +++  +  DG P   YI
Sbjct: 700 KEFKAVQKFSELFQLLPCREAEKPSNQPKNRKPGILPADFFRPILMSSLNADGSPA--YI 757

Query: 262 NA 263
           NA
Sbjct: 758 NA 759


>UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;
           n=2; Caenorhabditis|Rep: Protein tyrosine phosphatase
           protein 2 - Caenorhabditis elegans
          Length = 668

 Score =  132 bits (319), Expect = 3e-29
 Identities = 81/205 (39%), Positives = 119/205 (58%), Gaps = 12/205 (5%)

Query: 73  RWYHGQLTAKEAERMMMENGKNGSFLVRESQSQPGDFVLSVRTRDRVTHVIIRRKDN--K 130
           RW+HG L A  A +++ +  KNG++L+R SQ  PG  V+S +T  +V H+ I +  +  +
Sbjct: 133 RWWHGNLPASSANKLL-QTEKNGTYLLRASQHIPGALVISAKTEGQVVHLTIYQDPSTGR 191

Query: 131 YDVGGGQ-QFDDLVSLIEYYRSFPMVET--TGEVLRLIQPFNATRIQVRHFHTRVKQLQK 187
           +++ G + +F     LI+ Y   P+VE      VL L +P   T I+   F  R + +++
Sbjct: 192 FNIDGDRTKFQSAWLLIDSYSKNPIVEKGEASRVLYLEEPLFNTFIEADLFVDRFEIIRR 251

Query: 188 ENEGPIESMAYKQGFWEEFETL--QMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRV 245
               P ESM  K G  EEF+ L  + +   Q   + EG +P N  KNRYKNI+PFDHTRV
Sbjct: 252 PIN-PRESME-KTGISEEFDRLSQEALPAEQYLSKREGRRPVNAEKNRYKNIVPFDHTRV 309

Query: 246 ILKDIPPDGPPGSDYINANYIRCDS 270
           IL D P    PGSDYINA+Y+R ++
Sbjct: 310 ILTDRP--NTPGSDYINASYVRFEN 332



 Score =  109 bits (261), Expect = 3e-22
 Identities = 68/188 (36%), Positives = 101/188 (53%), Gaps = 14/188 (7%)

Query: 391 DVRIIIMTTKEIERG---KVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTK 447
           D+ +     ++++R    +VK E      N+  + K      E       Y LR  LV K
Sbjct: 402 DISLTCTIERKVQRAVSDEVKAELEQEKTNR--IAKGLVPEAELNGDGISYILRT-LVMK 458

Query: 448 KDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN----YRLQQIMTGTDPPAQAVV 503
           K + T  R I    +  WPDH  P  P  VLN L DV+    Y   Q +  + P  Q  +
Sbjct: 459 KGKDT--REIRQLQYLTWPDHGCPLHPYAVLNFLEDVDREYDYFNAQPIAASLP--QGPI 514

Query: 504 CVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIY 563
            VHCSAGIGRTGT +V+D +L+Q++K G  C +D+++ V+ VR  RSG+VQ E QY+F+Y
Sbjct: 515 VVHCSAGIGRTGTVLVLDALLNQVKKVGLLCPMDVYKMVKYVRTYRSGLVQTEQQYQFLY 574

Query: 564 MAVLEFIE 571
            A+  +++
Sbjct: 575 KALAFYLK 582



 Score = 80.2 bits (189), Expect = 1e-13
 Identities = 41/86 (47%), Positives = 55/86 (63%), Gaps = 7/86 (8%)

Query: 339 PNPNYFNTTIPK--SATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIII 396
           P  +Y N +  +  ++  T+N         K++IATQGCL TTI  FWSM+WQE+ R+I+
Sbjct: 318 PGSDYINASYVRFENSQRTKN---VTFACEKSFIATQGCLETTISDFWSMVWQENSRVIV 374

Query: 397 MTTKEIERGKVKCERYWP-DLNKTEV 421
           M T E ER K KC RYWP ++NK EV
Sbjct: 375 MPTMENER-KEKCARYWPAEVNKPEV 399



 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 37/99 (37%), Positives = 52/99 (52%), Gaps = 9/99 (9%)

Query: 7   FHPSLNGVDAEKLLMECGHDGYFLARPSSSNKGDFTLSVR-RGNEVTHIKI-QNNGEFLD 64
           F+  +NG  AE+LL E G DG FL R S SN  +F++SVR   +++ HIK+ +   + L 
Sbjct: 11  FYYRVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLS 70

Query: 65  LYGDPTTERWYHGQLTAKEAERMMME-----NGKNGSFL 98
           ++ D  T     G +T  E     ME       KNG FL
Sbjct: 71  IFEDERTTPNQFGSIT--ELAEFYMEFPEKLREKNGLFL 107



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 29/102 (28%), Positives = 56/102 (54%), Gaps = 9/102 (8%)

Query: 75  YHGQLTAKEAERMMMENGKNGSFLVRESQSQPGDFVLSVR-TRDRVTHVIIRRKDN---- 129
           ++ ++  ++AE ++ E G++G FL+R S+S P +F +SVR   D++ H+ + + ++    
Sbjct: 11  FYYRVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIKVTKYESDMLS 70

Query: 130 --KYDVGGGQQFDDLVSLIEYYRSFP--MVETTGEVLRLIQP 167
             + +     QF  +  L E+Y  FP  + E  G  L L +P
Sbjct: 71  IFEDERTTPNQFGSITELAEFYMEFPEKLREKNGLFLELKKP 112


>UniRef50_Q20120 Cluster: Putative uncharacterized protein dep-1; n=2;
            Caenorhabditis|Rep: Putative uncharacterized protein
            dep-1 - Caenorhabditis elegans
          Length = 1367

 Score =  132 bits (319), Expect = 3e-29
 Identities = 92/273 (33%), Positives = 134/273 (49%), Gaps = 25/273 (9%)

Query: 304  VHTSVIVTEEPVKSSKKVHGNGTHKLPAFEPSVLR-PNPNYFNTTIPKSATETENGVPTV 362
            V  SV  +E P+   K    N    +P+++ S ++  NPN     I        N VP  
Sbjct: 1084 VGQSVAASELPINRPKNRFTN----IPSYDHSRVKLSNPN----NIEGGDYINANYVPGF 1135

Query: 363  HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
                + +IA QG L TT   FW M W++    II  TK +E+G+ KC +YWPD     V+
Sbjct: 1136 SS-RREFIAAQGPLPTTRDHFWQMTWEQQCPAIIALTKCVEKGRDKCHQYWPDHENVPVL 1194

Query: 423  K---KYTILNEFESSTPDYTLRRFLVTKK-DETTVKRTIYHFHFTAWPDHRVPSEPGRVL 478
                + TI+ E E    ++ +R   + K   +  V R + H+H+ AWPD   PS P  ++
Sbjct: 1195 YGDIEVTIVAEKEFD--EFVIRDIRLEKSGPDGRVTRFVRHWHYMAWPDFGAPSHPNGII 1252

Query: 479  NILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
                   + L         P  A   VHCSAG+GR+GTFI ID +L   +   F   ID+
Sbjct: 1253 QFSRMFRHHLPH------SPHNAPTIVHCSAGVGRSGTFISIDRLL---QSSSFGDPIDV 1303

Query: 539  HRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
              TV  +R +R  MVQNE QY FI+  +L+ ++
Sbjct: 1304 FGTVCEMRYERCQMVQNEQQYIFIHYCILQVLQ 1336



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 26/61 (42%), Positives = 36/61 (59%), Gaps = 3/61 (4%)

Query: 207  ETLQMMENLQLFDRMEGSK-PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANY 265
            E   MM N+ +   +  S+ P N  KNR+ NI  +DH+RV L +  P+   G DYINANY
Sbjct: 1074 EEYDMMRNVGVGQSVAASELPINRPKNRFTNIPSYDHSRVKLSN--PNNIEGGDYINANY 1131

Query: 266  I 266
            +
Sbjct: 1132 V 1132


>UniRef50_A1ZAB3 Cluster: CG18243-PA; n=2; Sophophora|Rep: CG18243-PA
            - Drosophila melanogaster (Fruit fly)
          Length = 1419

 Score =  132 bits (319), Expect = 3e-29
 Identities = 76/236 (32%), Positives = 120/236 (50%), Gaps = 21/236 (8%)

Query: 363  HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP--DLNKTE 420
            H   K YIATQG    ++  FW MI Q +VR+I+  T+  E   +KC  Y+P      T 
Sbjct: 1146 HTRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYPYNVRGLTV 1205

Query: 421  VVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNI 480
             +K   +L  ++        R  L    D+  +K  + H++F  WPDH VP +P  ++  
Sbjct: 1206 TIKSKEVLELYD--------RTELTVVHDKYGLKEKVIHYYFKKWPDHGVPEDPMHLIMF 1257

Query: 481  LLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHR 540
            +  V    +        P+ + + VHCSAG+GRTGTFI +D+I+ +++ E    +I+I  
Sbjct: 1258 VKKVKAEKR--------PSYSPIVVHCSAGVGRTGTFIGLDLIMQRLKSES---KINIFE 1306

Query: 541  TVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDSPRARSMPVP 596
            TV+ +R QR  MVQ + QY F+Y    E ++ +  R  L  +    S    ++P P
Sbjct: 1307 TVKKLRFQRMKMVQTQQQYTFLYACTYELVKHKIPRAALKMDGRPKSVTVPAIPSP 1362



 Score = 39.5 bits (88), Expect = 0.25
 Identities = 21/36 (58%), Positives = 26/36 (72%), Gaps = 4/36 (11%)

Query: 231  KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            KNRY +I P+D  RVIL DI  +   GSDYINA++I
Sbjct: 1112 KNRYADIFPYDKNRVIL-DIDAE---GSDYINASFI 1143


>UniRef50_P23470 Cluster: Receptor-type tyrosine-protein phosphatase
            gamma precursor; n=33; Euteleostomi|Rep: Receptor-type
            tyrosine-protein phosphatase gamma precursor - Homo
            sapiens (Human)
          Length = 1445

 Score =  132 bits (319), Expect = 3e-29
 Identities = 82/214 (38%), Positives = 116/214 (54%), Gaps = 22/214 (10%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIATQG L +T   FW MIW+++  II+M T  +E+G+ KC++YWP  N  E      
Sbjct: 919  KAYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIV 978

Query: 427  ILNEFESSTPDYTLRRFLV----TKKDE------TTVKRTIYHFHFTAWPDHRVPSEPGR 476
             L   +     YT+RRF +     KK +         +R +  +H+T WPD  VP     
Sbjct: 979  TLKSTKIHA-CYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPE---Y 1034

Query: 477  VLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEI 536
             L +L  V       M  T P     V VHCSAG+GRTGT+IVID +L QI+ +     +
Sbjct: 1035 ALPVLTFVRRSSAARMPETGP-----VLVHCSAGVGRTGTYIVIDSMLQQIKDKS---TV 1086

Query: 537  DIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
            ++   ++ +R QR+ +VQ E QY FI+ A+LE I
Sbjct: 1087 NVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAI 1120



 Score = 60.5 bits (140), Expect = 1e-07
 Identities = 29/68 (42%), Positives = 39/68 (57%)

Query: 199 KQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGS 258
           + GF E+FE +Q             + PEN  KNRY NI+ +DH+RV L+ +P      S
Sbjct: 845 QHGFSEDFEEVQRCTADMNITAEHSNHPENKHKNRYINILAYDHSRVKLRPLPGKDSKHS 904

Query: 259 DYINANYI 266
           DYINANY+
Sbjct: 905 DYINANYV 912



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 48/218 (22%), Positives = 88/218 (40%), Gaps = 22/218 (10%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            +I TQ  L  T   FW MIW  + +II+M        + +   YWP   ++   + +T+ 
Sbjct: 1220 FIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWPSREESMNCEAFTVT 1278

Query: 429  ----NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVP-SEPGRVLNILLD 483
                +    S  +  +    + +  +      + HF    WP+   P S    ++N++ +
Sbjct: 1279 LISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKE 1338

Query: 484  VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
                  + +T   P       VH   G    G    +  +  Q+  E     +D+ +  +
Sbjct: 1339 ------EALTRDGP-----TIVHDEYGAVSAGMLCALTTLSQQLENEN---AVDVFQVAK 1384

Query: 544  MVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGP 581
            M+   R G+  +  QY+FIY A L  + T++   G GP
Sbjct: 1385 MINLMRPGVFTDIEQYQFIYKARLSLVSTKEN--GNGP 1420



 Score = 38.7 bits (86), Expect = 0.44
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 2/53 (3%)

Query: 214  NLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            N +  +     K  N  KNR  +++P +  RV L  +P  G  G+DYINA+YI
Sbjct: 1161 NAKYVECFSAQKECNKEKNRNSSVVPSERARVGLAPLP--GMKGTDYINASYI 1211


>UniRef50_UPI0000D5709F Cluster: PREDICTED: similar to CG31795-PA,
            isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
            similar to CG31795-PA, isoform A - Tribolium castaneum
          Length = 1014

 Score =  132 bits (318), Expect = 3e-29
 Identities = 79/221 (35%), Positives = 116/221 (52%), Gaps = 13/221 (5%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
            N  YIATQG L  T   FW +IW++   +I+M T+  E G   C RYWP+   +E+   Y
Sbjct: 800  NPAYIATQGPLPLTAPDFWQLIWEQGAVVIVMLTRLTEGGAAMCHRYWPE-EGSELYHIY 858

Query: 426  TI-LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
             + L        DY +R F + K  +T   RT+  FHF +WP+  VP+        LL+ 
Sbjct: 859  EVHLVSEHIWCDDYLVRSFYL-KNVKTGETRTVTQFHFLSWPESGVPAS----TKALLEF 913

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
              ++ +   G   P    + VHCS G GRTGT+ +IDM+L ++ K     EIDI  T++ 
Sbjct: 914  RRKVNKSYRGRSCP----IVVHCSDGAGRTGTYCLIDMVLSRMAKGA--KEIDIAATLEH 967

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQ 585
            +RDQR  MV  + Q++F+  AV E +    + +   P  AQ
Sbjct: 968  LRDQRPRMVATKQQFEFVLTAVAEEVHAILKALPPQPSPAQ 1008



 Score = 52.4 bits (120), Expect = 3e-05
 Identities = 24/48 (50%), Positives = 33/48 (68%), Gaps = 2/48 (4%)

Query: 219 DRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           D    +K EN+ KNRY +IIP+DH+RV+L ++      GSDYINA+ I
Sbjct: 748 DTSIATKKENLEKNRYPDIIPYDHSRVVLNEL--SNASGSDYINASSI 793


>UniRef50_Q90947 Cluster: Phosphotyrosyl phosphatase; n=5;
           Tetrapoda|Rep: Phosphotyrosyl phosphatase - Gallus
           gallus (Chicken)
          Length = 832

 Score =  132 bits (318), Expect = 3e-29
 Identities = 76/218 (34%), Positives = 121/218 (55%), Gaps = 19/218 (8%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           K YIA QG L +T   FW MIW+ +V +I+M T  +E+G+ KC++YWP    +E    + 
Sbjct: 312 KAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLLEKGRRKCDQYWP-AEGSEEYGNFL 370

Query: 427 ILNEFESSTPDYTLRRFLV--TKKDETTVK-----RTIYHFHFTAWPDHRVPSEPGRVLN 479
           +  +       YT+R F +  TK  + + K     R +  +H+T WPD  VP     VL 
Sbjct: 371 VTQKSVHVLAYYTVRNFTLRNTKIKKGSQKGRSSGRVVTQYHYTQWPDMGVPEYTLPVLT 430

Query: 480 ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
            +   ++  +         A   + VHCSAG+GRTGT++V+D +L QI+ EG    ++I 
Sbjct: 431 FVRKASHAKRH--------AVGPIVVHCSAGVGRTGTYVVLDSMLQQIQHEG---TVNIF 479

Query: 540 RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
             ++ +R QR+ +VQ E QY FI+ A++E I +++  V
Sbjct: 480 GFLKHIRTQRNYLVQTEEQYIFIHDALVEAILSKETEV 517



 Score = 67.7 bits (158), Expect = 8e-10
 Identities = 55/224 (24%), Positives = 99/224 (44%), Gaps = 23/224 (10%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKT---EVVKKY 425
           +I TQ  L  TI  FW MIW  + ++I+M        + +   YWP+ ++    E  K  
Sbjct: 609 FIITQHPLLHTIKDFWRMIWDHNAQLIVMLPDSQNMAEDEFV-YWPNKDEPINCETFKVT 667

Query: 426 TILNEFE--SSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
            I  E +  S      ++ F++    +  V   + HF    WP+   P  P      L+ 
Sbjct: 668 MIAEEHKCLSKEEKLIIQDFILEATQDDYVLE-VRHFQCPKWPN---PDSPISKTFELIS 723

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
           +   +++  +  D P    + VH   G    GTF  +  ++ Q+  E     +D+++  +
Sbjct: 724 I---IKEETSNRDGP----MIVHDEHGGVTAGTFCALTTLMHQLENEN---SVDVYQVAK 773

Query: 544 MVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDS 587
           M+   R G+  +  QY+F+Y A+L  + T ++     P A+ DS
Sbjct: 774 MINLMRPGVFTDIEQYQFLYKAILSLVSTRQEE---NPSASMDS 814



 Score = 54.4 bits (125), Expect = 8e-06
 Identities = 28/66 (42%), Positives = 36/66 (54%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF EEFE +Q             + P+N  KNRY NI+ +DHTRV L  +       +DY
Sbjct: 240 GFSEEFEEIQSCTVDLGITSDSSNHPDNKNKNRYINIVAYDHTRVKLAQLAEKDGKLTDY 299

Query: 261 INANYI 266
           INANY+
Sbjct: 300 INANYV 305



 Score = 37.1 bits (82), Expect = 1.3
 Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)

Query: 204 EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
           ++F+ L    N Q  D     K  N  KNR  +IIP + +RV +  +  +   G+DYINA
Sbjct: 542 KQFKLLSQ-SNTQQCDYSTALKQCNREKNRTSSIIPVERSRVGISSLSGE---GTDYINA 597

Query: 264 NYI 266
           +YI
Sbjct: 598 SYI 600


>UniRef50_UPI00015B6015 Cluster: PREDICTED: hypothetical protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
           protein - Nasonia vitripennis
          Length = 619

 Score =  131 bits (317), Expect = 4e-29
 Identities = 79/209 (37%), Positives = 115/209 (55%), Gaps = 19/209 (9%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
           YIATQG LS TI  FWSM W E   +IIM T+  E  K KCE Y+P +LN       +T+
Sbjct: 417 YIATQGPLSHTIADFWSMAWAERTPVIIMITRLHEAAKTKCEAYFPLELNSRIQAGPFTV 476

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
           +     +   Y++R   V  ++E   +R I H+ + +WPDH VP     ++ +  ++N  
Sbjct: 477 ILNSMDTRGGYSVRDLEVRYENE---RRIIQHYWYDSWPDHLVPQTADALVGLAAEIN-- 531

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                T T P     + VHCSAGIGRTG FI +   + Q+ +EG    +DI R +  +R 
Sbjct: 532 -----TLTGP-----IIVHCSAGIGRTGCFIALATGMTQLIREG---NVDILRILCQMRY 578

Query: 548 QRSGMVQNEAQYKFIYMAVLEFIETEKQR 576
            R GMVQ   QY+F++ A+  F ET +++
Sbjct: 579 DRGGMVQTAEQYEFLHKALCLFEETLERK 607



 Score = 36.3 bits (80), Expect = 2.3
 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 231 KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           KNRY  ++P   +RVIL   P    P + YINANY+R
Sbjct: 376 KNRYPTVLPNARSRVIL---PGSEDPLTSYINANYVR 409


>UniRef50_UPI0000D567E0 Cluster: PREDICTED: similar to Receptor-type
           tyrosine-protein phosphatase mu precursor
           (Protein-tyrosine phosphatase mu) (R-PTP-mu); n=1;
           Tribolium castaneum|Rep: PREDICTED: similar to
           Receptor-type tyrosine-protein phosphatase mu precursor
           (Protein-tyrosine phosphatase mu) (R-PTP-mu) - Tribolium
           castaneum
          Length = 566

 Score =  131 bits (317), Expect = 4e-29
 Identities = 75/206 (36%), Positives = 109/206 (52%), Gaps = 14/206 (6%)

Query: 363 HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
           H  +K YIATQG  + T+  FW M+W+++V  I       E GK K E+YWPD+N+T   
Sbjct: 142 HKISKAYIATQGPKAVTLNDFWRMVWEQNVMHIANLANVYEGGKKKVEKYWPDINETLQF 201

Query: 423 KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
              ++ +       DY  R F V + +E    R I   HF +WPDH VP     ++  L 
Sbjct: 202 GTISVQHLSTQVFADYEHRFFSVCQNNEI---RKIDQLHFMSWPDHGVPLYSQSLVPFL- 257

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
               +L +    T  P    + VHCSAG+GRTGT ++ D+ L    +EG    ID+ R +
Sbjct: 258 ---QKLLKFPLSTYSP----IVVHCSAGVGRTGTILLCDICLRMAAREG---TIDVLRNL 307

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLE 568
           + +R QR+ MV N  QYK  ++ +LE
Sbjct: 308 EHLRQQRANMVDNIEQYKLAHLVILE 333



 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 26/44 (59%), Positives = 31/44 (70%), Gaps = 2/44 (4%)

Query: 223 GSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           GS  EN  KNRY N+I +DH+RVIL+ I   G   SDYINA+YI
Sbjct: 98  GSLKENKSKNRYNNLIAYDHSRVILQKI--KGDSYSDYINASYI 139



 Score = 37.1 bits (82), Expect = 1.3
 Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 1/53 (1%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV 421
           +I TQ  +  T+  FW ++ + D+R+I+       + K  C R+WP  +  E+
Sbjct: 436 FIVTQQPMPNTLGDFWRLVEENDIRVILSLNDVNLKNKTSC-RFWPTRSNPEM 487


>UniRef50_Q7QBG0 Cluster: ENSANGP00000003247; n=3; Culicidae|Rep:
            ENSANGP00000003247 - Anopheles gambiae str. PEST
          Length = 1458

 Score =  131 bits (316), Expect = 6e-29
 Identities = 73/209 (34%), Positives = 115/209 (55%), Gaps = 21/209 (10%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K +I  QG +  TI  FW MIW++ + II+M T   E  K KC +YWP+ +  + ++   
Sbjct: 956  KKFICAQGPMDATINDFWRMIWEQHLEIIVMLTNLEEYNKTKCAKYWPE-STNDSIQYGE 1014

Query: 427  ILNEFESST--PDYTLRRFLVTKKDETT---VKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
            +L  F+S T   DY +R   VTK+  ++     R I  +H+ AW D   P  P  +   +
Sbjct: 1015 LLITFQSLTYYADYIIRTLKVTKRSASSGEETSREISQYHYLAWKDFMAPEHPQGITKFI 1074

Query: 482  LDVN--YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
              +N  Y LQ          +  + VHCSAG+GRTGTF+ +D ++ Q+++EG   ++ I 
Sbjct: 1075 NRINSEYSLQ----------RGPILVHCSAGVGRTGTFVALDTLMQQLQEEG---QVFIF 1121

Query: 540  RTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
             T+  +R QR+ +VQ+  QY F+Y A+ E
Sbjct: 1122 NTICDMRYQRNFLVQSLKQYIFLYRALAE 1150



 Score = 97.9 bits (233), Expect = 7e-19
 Identities = 65/214 (30%), Positives = 110/214 (51%), Gaps = 17/214 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            ++ TQ  +  TI+ FW MI+++ ++ I+M + EI  G  KC RYW D    E +K   +L
Sbjct: 1255 FVITQDPMEDTIFDFWRMIFEQRIKTIVMFS-EIGDGPNKCPRYWAD----EEMKYENLL 1309

Query: 429  NEF--ESSTPDYTLRRFLVTK-KDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
              +    S P YT R F VT  K   T+  T   F +  WP   V  E   V   ++++ 
Sbjct: 1310 VSYIQSESGPYYTKREFTVTNCKTNDTIHVT--QFQYNGWPT--VEGEVPEVTRGMIEIV 1365

Query: 486  YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
             + Q+    +       + VHCS G  ++  F+ + +++ Q++ E     +DI   V+ +
Sbjct: 1366 NQAQK--HSSQQQDIFTIAVHCSLGTDKSSLFVAMCILVMQLKTEK---RVDICTVVRKL 1420

Query: 546  RDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGL 579
            R QRS M+Q  AQY+F++ A++ F +  K  +G+
Sbjct: 1421 RAQRSLMIQTYAQYEFLHRAIVNFADLYKISLGI 1454



 Score = 45.6 bits (103), Expect = 0.004
 Identities = 28/66 (42%), Positives = 35/66 (53%), Gaps = 4/66 (6%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF  EFE L   +             EN+ KNRY +I  +D TRV  K  P +G  GSDY
Sbjct: 888 GFQHEFELLP--DKFADRTTKNSDMKENMPKNRYPDIKAYDQTRV--KLTPLNGLAGSDY 943

Query: 261 INANYI 266
           INAN++
Sbjct: 944 INANFV 949



 Score = 41.5 bits (93), Expect = 0.062
 Identities = 22/44 (50%), Positives = 27/44 (61%), Gaps = 2/44 (4%)

Query: 223  GSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            GS  EN  KNR ++ IP+D  RVIL  IP  G     YINA++I
Sbjct: 1205 GSSEENKAKNRSESCIPYDKNRVILAPIP--GRDNCTYINASFI 1246


>UniRef50_Q62656 Cluster: Receptor-type tyrosine-protein phosphatase
            zeta precursor; n=13; Amniota|Rep: Receptor-type
            tyrosine-protein phosphatase zeta precursor - Rattus
            norvegicus (Rat)
          Length = 2316

 Score =  131 bits (316), Expect = 6e-29
 Identities = 79/218 (36%), Positives = 120/218 (55%), Gaps = 19/218 (8%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIA QG L +T   FW MIW+ +V +I+M T  +E+G+ KC++YWP  + +E    + 
Sbjct: 1796 KAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWP-TDGSEEYGSFL 1854

Query: 427  ILNEFESSTPDYTLRRFLV--TKKDETTVK-----RTIYHFHFTAWPDHRVPSEPGRVLN 479
            +  +       YT+R F +  TK  + + K     R +  +H+T WPD  VP      L 
Sbjct: 1855 VNQKNVQVLAYYTVRNFTLRNTKIKKGSQKGRSSGRLVTQYHYTQWPDMGVPEYS---LP 1911

Query: 480  ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
            +L  V    Q       P     V VHCSAG+GRTGT+IV+D +L QI+ EG    ++I 
Sbjct: 1912 VLAFVRKTAQAKRHAVGP-----VVVHCSAGVGRTGTYIVLDSMLQQIQHEG---TVNIF 1963

Query: 540  RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
              ++ +R QR+ +VQ E QY FI+  ++E I +++  V
Sbjct: 1964 GFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEV 2001



 Score = 64.9 bits (151), Expect = 6e-09
 Identities = 54/225 (24%), Positives = 98/225 (43%), Gaps = 25/225 (11%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK----K 424
            +I TQ  L  TI  FW MIW  + ++++M        + +   YWP  NK E +     K
Sbjct: 2093 FIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQNMAEDEFV-YWP--NKDEPINCESFK 2149

Query: 425  YTILNEFES--STPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
             T+++E     S  +  + +  + +  +      + HF    WP+   P  P      L+
Sbjct: 2150 VTLMSEEHKCLSNEEKLIVQDFILEATQDDYVLEVRHFQCPKWPN---PDSPISKTFELI 2206

Query: 483  DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
             +   +++     D P    + VH   G    GTF  +  ++ Q+ KE     +D+++  
Sbjct: 2207 SI---IKEEAANRDGP----MIVHDEHGGVTAGTFCALTTLMHQLEKEN---SMDVYQVA 2256

Query: 543  QMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDS 587
            +M+   R G+  +  QY+F+Y  VL  + T ++     P  + DS
Sbjct: 2257 KMINLMRPGVFTDIEQYQFLYKVVLSLVSTRQEE---NPSTSLDS 2298



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 173  IQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKN 232
            I ++HF   V  L   N G  E     + F++E ++  +   +        + P+N  KN
Sbjct: 1700 IPIKHFPKHVADLHASN-GFTEEFETLKEFYQEVQSCTVDLGITADS---SNHPDNKHKN 1755

Query: 233  RYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            RY NI+ +DH+RV L  +       +DYINANY+
Sbjct: 1756 RYVNIVAYDHSRVKLTQLAEKDGKLTDYINANYV 1789



 Score = 36.3 bits (80), Expect = 2.3
 Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 4/63 (6%)

Query: 204  EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
            ++F+ L     LQ  D     K  N  KNR  +IIP + +RV +  +  +   G+DYINA
Sbjct: 2026 KQFQLLSQSNILQS-DYSTALKQCNREKNRTSSIIPVERSRVGISSLSGE---GTDYINA 2081

Query: 264  NYI 266
            +YI
Sbjct: 2082 SYI 2084


>UniRef50_Q15678 Cluster: Tyrosine-protein phosphatase non-receptor
            type 14; n=52; Tetrapoda|Rep: Tyrosine-protein
            phosphatase non-receptor type 14 - Homo sapiens (Human)
          Length = 1187

 Score =  130 bits (315), Expect = 8e-29
 Identities = 68/212 (32%), Positives = 116/212 (54%), Gaps = 11/212 (5%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL---NKTEVVKKY 425
            YIATQG L  T + FW M+W++ V +I M T E E G+ K  RYWP L   + +    K+
Sbjct: 979  YIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKF 1038

Query: 426  TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD-- 483
             +  +F + +  Y     L  K   +  +RT++H  +T WPDH  P +    L+ L +  
Sbjct: 1039 KVTTKFRTDSVCYATTG-LKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQ 1097

Query: 484  -VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
             V      ++ GT      +V VHCSAG+GRTG  I+ ++++  +       ++++   +
Sbjct: 1098 SVRRHTNSMLEGTKNRHPPIV-VHCSAGVGRTGVLILSELMIYCLEHNE---KVEVPMML 1153

Query: 543  QMVRDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
            +++R+QR  M+Q  AQYKF+Y  +++F++  +
Sbjct: 1154 RLLREQRMFMIQTIAQYKFVYQVLIQFLQNSR 1185


>UniRef50_UPI00015A519A Cluster: Receptor-type tyrosine-protein
           phosphatase gamma precursor (EC 3.1.3.48)
           (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).;
           n=4; Euteleostomi|Rep: Receptor-type tyrosine-protein
           phosphatase gamma precursor (EC 3.1.3.48)
           (Protein-tyrosine phosphatase gamma) (R-PTP-gamma). -
           Danio rerio
          Length = 705

 Score =  130 bits (314), Expect = 1e-28
 Identities = 76/214 (35%), Positives = 115/214 (53%), Gaps = 22/214 (10%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           K YIA QG L +T   FW M+W+++  II+M T  +E+G+ KC++YWP  N  E      
Sbjct: 179 KAYIAAQGPLKSTFEDFWRMVWEQNTGIIVMITNLVEKGRRKCDQYWPSENSEEYGNIVV 238

Query: 427 ILNEFESSTPDYTLRRFLV----TKKDE------TTVKRTIYHFHFTAWPDHRVPSEPGR 476
            L   +     YTLR F +     KK +         +RT+  +H+T WPD  VP     
Sbjct: 239 TLKRTKVMA-CYTLRIFTIRNTKVKKGQKGNTKGRQSERTVLQYHYTQWPDMGVPEYTLP 297

Query: 477 VLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEI 536
           VL  +        +  +    P    + VHCSAG+GRTGT+IVID +L Q++ +G    +
Sbjct: 298 VLTFV--------RKSSAAQTPDMGPMLVHCSAGVGRTGTYIVIDSMLQQLKDKG---AV 346

Query: 537 DIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
           ++   ++ +R QR+ +VQ E QY FI+ A++E I
Sbjct: 347 NVLGFLKHIRTQRNYLVQTEEQYIFIHDALMEAI 380



 Score = 60.1 bits (139), Expect = 2e-07
 Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 9/100 (9%)

Query: 167 PFNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKP 226
           P +   I V+HF   V +L   N+          GF ++FE +Q             + P
Sbjct: 82  PDDMEAIPVKHFIKHVSELYSNNQ---------HGFSDDFEEVQRCTADMKITAEHSNHP 132

Query: 227 ENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           +N  KNRY NII +DH+RV L+ +       SDYINANY+
Sbjct: 133 DNKHKNRYINIIAYDHSRVKLRPLAGKDSKHSDYINANYV 172



 Score = 57.6 bits (133), Expect = 9e-07
 Identities = 48/212 (22%), Positives = 88/212 (41%), Gaps = 22/212 (10%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCE-RYWPDLNKTEVVKKYTI 427
           +I TQ  L  T   FW MIW  + +II+M      +G  + E  YWP   +    + +T+
Sbjct: 480 FIITQHPLPHTTKDFWRMIWDHNAQIIVMLPD--NQGLAEDEFVYWPSREEAMNCEAFTV 537

Query: 428 L----NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVP-SEPGRVLNILL 482
                +    S  +  +    + +  +      + HF    WP+   P S    ++N++ 
Sbjct: 538 TLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVI- 596

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
                 ++ MT   P       VH   G    G F  +  +  Q+  EG      +++  
Sbjct: 597 -----KEEAMTRDGP-----TIVHDEFGAVSAGMFCALTTLSQQLESEG---AAGVYQVA 643

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
           +M+   R G+  +  QY+++Y A+L  I T++
Sbjct: 644 KMINLMRPGVFTDIEQYQYLYKAMLSLISTKE 675



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 2/53 (3%)

Query: 214 NLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N +  +     K  N  KNR  +++P +  RV L  +P  G  G+DYINA+YI
Sbjct: 421 NARFVECFSAQKDCNKEKNRNSSVVPSERARVGLAPLP--GMKGTDYINASYI 471


>UniRef50_Q4D9I2 Cluster: Tyrosine specific protein phosphatase,
           putative; n=2; Trypanosoma cruzi|Rep: Tyrosine specific
           protein phosphatase, putative - Trypanosoma cruzi
          Length = 668

 Score =  130 bits (314), Expect = 1e-28
 Identities = 71/199 (35%), Positives = 104/199 (52%), Gaps = 12/199 (6%)

Query: 368 TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI 427
           TYIATQ  L  TI+ FW M+++ DV  ++M   E+E GK K E YWP  N    +    I
Sbjct: 107 TYIATQAPLQNTIFDFWRMVFENDVVFVVMLCGEVEDGKAKSEMYWPKENGVLDIGILQI 166

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            +  E    D   R F++  ++    +  +YH  +  WPD  +P     ++ I+      
Sbjct: 167 SSISEKRLSDLVFRSFIL--RNANGEEHQVYHMQYIGWPDQGIPDTSAPLMEII------ 218

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
             Q M  ++   Q  + VHCS GIGRTG FI + + L Q + E  D  IDI R V +++ 
Sbjct: 219 --QTMGKSELSVQTPIVVHCSGGIGRTGVFIALHVALAQFQLERKD--IDIKRIVHILKL 274

Query: 548 QRSGMVQNEAQYKFIYMAV 566
            R+GMVQ + QY F+Y +V
Sbjct: 275 SRTGMVQRKDQYVFLYYSV 293


>UniRef50_UPI0000D56952 Cluster: PREDICTED: similar to CG10975-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG10975-PA, isoform A - Tribolium castaneum
          Length = 516

 Score =  130 bits (313), Expect = 1e-28
 Identities = 74/202 (36%), Positives = 106/202 (52%), Gaps = 15/202 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           + +IATQ  + +TI  FW M+WQE+V+ IIM T+ +E    KC +YWP+L       K  
Sbjct: 105 RAFIATQAPMESTIGDFWWMVWQENVKNIIMLTELVENNVEKCAQYWPELKSHVRYGKIL 164

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           I N ++    D+  R+  V   +E    RTI H  F  WPDH+VP  P      +     
Sbjct: 165 IRNTYQKIHADFIQRKLSVRCNNE---NRTIQHLQFVTWPDHQVPLYPQNFTKFV----- 216

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
           R    M    P  ++ + VHC+AG GRTGT I+ D +L    KE    ++D  +T+  +R
Sbjct: 217 RTMVAM----PLNKSRIVVHCNAGCGRTGTLILCDTVLRMAAKE---TKLDFVKTLTNMR 269

Query: 547 DQRSGMVQNEAQYKFIYMAVLE 568
            QR+ +V N  QY F +  VLE
Sbjct: 270 QQRTNLVSNVDQYIFAHFIVLE 291



 Score = 48.8 bits (111), Expect = 4e-04
 Identities = 26/47 (55%), Positives = 29/47 (61%), Gaps = 5/47 (10%)

Query: 220 RMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           R  G    N+ KNRYKNII FD TRV LKD       G DYINA+Y+
Sbjct: 57  RTVGLLKRNVAKNRYKNIIAFDETRVKLKDY-----DGYDYINASYV 98


>UniRef50_Q9Y1X5 Cluster: SPTPR2B; n=1; Ephydatia fluviatilis|Rep:
           SPTPR2B - Ephydatia fluviatilis
          Length = 478

 Score =  130 bits (313), Expect = 1e-28
 Identities = 68/206 (33%), Positives = 113/206 (54%), Gaps = 12/206 (5%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
           +I TQ  ++ T+  FW M+W+     I+M  + +E GK  C RYWP ++ + EV  KY +
Sbjct: 275 FIVTQAPMAETVGDFWRMVWEHKSAAIVMLAQLVEDGKEVCVRYWPEEMGRPEVFGKYQV 334

Query: 428 LNEFES-STPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
               E  +   Y +R+F +   D     R +  FH+  WP+   P     ++  L+D   
Sbjct: 335 EKSTEDRNESTYIIRKFKICSIDNPQDNRMVTQFHYLMWPNRAAPENTKSIVE-LIDELQ 393

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
           R+Q+  +G  P     + VHC+ GIGRTGTF     ++D+++ E     +D  +T++ +R
Sbjct: 394 RVQR-KSGNGP-----ITVHCNDGIGRTGTFCAAYSMMDRVKVEQV---VDAFQTIKSMR 444

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIET 572
            QR+G++ + AQY F++ AVLEF+ T
Sbjct: 445 IQRAGLLDSLAQYIFLHSAVLEFLST 470



 Score =  111 bits (266), Expect = 7e-23
 Identities = 70/184 (38%), Positives = 93/184 (50%), Gaps = 16/184 (8%)

Query: 391 DVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVT---- 446
           D   I+M T   E  KVKC +YWP    T        L E E+   +Y++R F VT    
Sbjct: 3   DCPTIVMVTNLQEEDKVKCHQYWPSYGSTTYGHLKVTLKEVENLA-EYSIRTFSVTPISG 61

Query: 447 KKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVH 506
           +       R +  FHF  WPDH VP    +    LL    R+ +      P  +  + VH
Sbjct: 62  QSRSPMPVREVRQFHFLVWPDHGVP----QYATALLSFRKRISKY----HPLNRGPMAVH 113

Query: 507 CSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAV 566
           CSAG+GRTGTFI ID +L QI  E     +DI   V+ +R +R+ MVQ  AQY FI+ A+
Sbjct: 114 CSAGVGRTGTFICIDYVLKQIEGEAI---VDIFNFVRHMRYRRNYMVQTSAQYIFIHDAI 170

Query: 567 LEFI 570
           LE +
Sbjct: 171 LESV 174


>UniRef50_Q15256 Cluster: Receptor-type tyrosine-protein phosphatase
           R precursor; n=57; Euteleostomi|Rep: Receptor-type
           tyrosine-protein phosphatase R precursor - Homo sapiens
           (Human)
          Length = 657

 Score =  130 bits (313), Expect = 1e-28
 Identities = 76/200 (38%), Positives = 111/200 (55%), Gaps = 15/200 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           K +IATQG +  T+  FW M+WQED  +I+M TK  E+ + KC  YWP+  K  +  K  
Sbjct: 460 KAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNE-KCVLYWPE--KRGIYGKVE 516

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           +L    +   +YT+R  LV K+   T  + + H+ +T+WPDH+ P     +L ++LDV  
Sbjct: 517 VLVISVNECDNYTIRN-LVLKQGSHT--QHVKHYWYTSWPDHKTPDSAQPLLQLMLDVE- 572

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
             +    G  P     V VHCSAGIGRTG FI   +   Q+++EG    +D    V  +R
Sbjct: 573 EDRLASQGRGP-----VVVHCSAGIGRTGCFIATSIGCQQLKEEGV---VDALSIVCQLR 624

Query: 547 DQRSGMVQNEAQYKFIYMAV 566
             R GMVQ   QY+F++ A+
Sbjct: 625 MDRGGMVQTSEQYEFVHHAL 644



 Score = 35.5 bits (78), Expect = 4.1
 Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 3/54 (5%)

Query: 215 LQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPG-SDYINANYIR 267
           +   D  E   P +  KNRYK I+P   +RV L+  P +     S YINANYIR
Sbjct: 402 MNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLR--PKNVTDSLSTYINANYIR 453


>UniRef50_UPI0000E46DBF Cluster: PREDICTED: similar to non-receptor
           protein tyrosine phosphatase; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to non-receptor
           protein tyrosine phosphatase - Strongylocentrotus
           purpuratus
          Length = 440

 Score =  129 bits (312), Expect = 2e-28
 Identities = 76/236 (32%), Positives = 118/236 (50%), Gaps = 12/236 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP----DLNKTEVV 422
           + YI TQG L+ T+  FW M+W++D R IIM    +E  + KC  Y+P    + N  E++
Sbjct: 82  RKYILTQGPLTRTVCHFWQMVWEQDSRAIIMLNNFVENHQQKCADYFPRGQDNGNTDELL 141

Query: 423 KKYTILNE--FESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNI 480
            + T+L           Y + R L+ +   T   + I HFH+T W D  VP  P   L  
Sbjct: 142 CEDTLLKVTYLRQERHHYYIVRTLLLEDLVTQQTKEILHFHYTRWSDFSVPQSPAAFLQF 201

Query: 481 LLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHR 540
           L  V  R   ++    PP      +HCSAG+GR+GT  ++D  L QI K+G    +D+ +
Sbjct: 202 LHHVR-RSGSLVDNVGPPV-----IHCSAGVGRSGTLCLVDTCLVQIEKKGNTSGLDVRK 255

Query: 541 TVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDSPRARSMPVP 596
            +  +R  R G++Q   Q +F Y A+LE  +   +   LG    +++    S+P P
Sbjct: 256 QLLDMRRYRHGLIQTWQQLRFSYCAILEGSKVILRGDDLGSLTVENNTDVESIPPP 311


>UniRef50_UPI0000EB46AF Cluster: protein tyrosine phosphatase,
            receptor type, H precursor; n=3; Laurasiatheria|Rep:
            protein tyrosine phosphatase, receptor type, H precursor
            - Canis familiaris
          Length = 1038

 Score =  129 bits (312), Expect = 2e-28
 Identities = 70/207 (33%), Positives = 107/207 (51%), Gaps = 10/207 (4%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            +IA QG L  T+  FW ++W++    ++M T  +E G+VKCE YWP   K        + 
Sbjct: 825  FIAAQGPLPQTVGDFWRLVWEQQSHTLVMLTNCVESGQVKCEHYWPLDTKPCTYGHLQVT 884

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
             E E    ++T+R   +    E  +   I  FH+  WPDH VP  P  +L     +   L
Sbjct: 885  LEGEEVLENWTVRDLKLWHMQEQKMLH-IRQFHYMTWPDHSVPYSPDPILAFWKMLRQWL 943

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
             Q + G  P       +HCSAG+GRTGT I +D++L Q+ ++   C +     V+ +R+ 
Sbjct: 944  DQTVGGGPP------IIHCSAGVGRTGTLIALDVLLRQLERD--RC-VRPFNYVRKMRES 994

Query: 549  RSGMVQNEAQYKFIYMAVLEFIETEKQ 575
            R  MVQ EAQY F++  +L F++   Q
Sbjct: 995  RPLMVQTEAQYVFLHQCILRFLQQPDQ 1021



 Score = 56.8 bits (131), Expect = 2e-06
 Identities = 29/66 (43%), Positives = 43/66 (65%), Gaps = 4/66 (6%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF +E++ L +  + Q   +   S PEN  KNRY+N++P+D +RV LK  P    PGSDY
Sbjct: 754 GFEKEYQQLYLESHNQ--SQTVASAPENGAKNRYRNVLPYDWSRVSLK--PLQDEPGSDY 809

Query: 261 INANYI 266
           INA+++
Sbjct: 810 INASFM 815


>UniRef50_Q4SDY5 Cluster: Chromosome 13 SCAF14627, whole genome
            shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 13
            SCAF14627, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1188

 Score =  129 bits (312), Expect = 2e-28
 Identities = 71/190 (37%), Positives = 111/190 (58%), Gaps = 12/190 (6%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K +IA QG L  T+  FW M+W+++V+ ++M T+  E+G+VKCE+YW D   T+  +   
Sbjct: 854  KEFIAAQGPLPGTVKDFWRMVWEKNVQTLVMLTRCNEQGRVKCEQYW-DFG-TKRFENIN 911

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            + +  +    D+T+R F + K  +T   R++  FHFTAWPDH VP        +L+   +
Sbjct: 912  VTSVSDIPLEDWTIRDFDI-KNVKTAETRSVRQFHFTAWPDHGVP----ETTELLISFRH 966

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
             +++ M      +  V  VHCSAG+GRTGTFI ID ++ QI +E     +D++  V  +R
Sbjct: 967  LVREHMDQYSRHSPTV--VHCSAGVGRTGTFIAIDRLIFQIERENI---VDVYGIVHDLR 1021

Query: 547  DQRSGMVQNE 556
              R+ MVQ E
Sbjct: 1022 MHRTLMVQTE 1031



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 30/66 (45%), Positives = 38/66 (57%), Gaps = 4/66 (6%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF EEFE L+ +   Q   +      EN  KNRY N++P+D +RV L  I   G P  DY
Sbjct: 786 GFAEEFEDLKPVGTDQ--PKTAALILENKPKNRYNNVLPYDSSRVKLSII--HGSPYDDY 841

Query: 261 INANYI 266
           INANY+
Sbjct: 842 INANYM 847


>UniRef50_P17706 Cluster: Tyrosine-protein phosphatase non-receptor
           type 2; n=53; Eumetazoa|Rep: Tyrosine-protein
           phosphatase non-receptor type 2 - Homo sapiens (Human)
          Length = 415

 Score =  129 bits (312), Expect = 2e-28
 Identities = 71/204 (34%), Positives = 111/204 (54%), Gaps = 12/204 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK-- 424
           ++YI TQG L  T   FW M+WQ+  + ++M  + +E+  VKC +YWP  ++  + K+  
Sbjct: 81  RSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETG 140

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
           +++    E     YT+   L  +   +   RTI HFH+T WPD  VP  P   LN L  V
Sbjct: 141 FSVKLLSEDVKSYYTV-HLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKV 199

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
                   +G+  P      +HCSAGIGR+GTF ++D  L  + ++G D  I+I + +  
Sbjct: 200 R------ESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCL-VLMEKGDD--INIKQVLLN 250

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLE 568
           +R  R G++Q   Q +F YMA++E
Sbjct: 251 MRKYRMGLIQTPDQLRFSYMAIIE 274



 Score = 37.9 bits (84), Expect = 0.76
 Identities = 17/41 (41%), Positives = 28/41 (68%), Gaps = 6/41 (14%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           PEN  +NRY+++ P+DH+RV L++        +DYINA+ +
Sbjct: 40  PENRNRNRYRDVSPYDHSRVKLQNAE------NDYINASLV 74


>UniRef50_UPI000065D195 Cluster: Tyrosine-protein phosphatase
            non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine
            phosphatase D1).; n=9; Euteleostomi|Rep: Tyrosine-protein
            phosphatase non-receptor type 21 (EC 3.1.3.48)
            (Protein-tyrosine phosphatase D1). - Takifugu rubripes
          Length = 1255

 Score =  128 bits (310), Expect = 3e-28
 Identities = 74/210 (35%), Positives = 109/210 (51%), Gaps = 8/210 (3%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL---NKTEVVKKY 425
            YIA+QG LS T   FW M+W++ V II M T E ERG+ K  RYWP L   + T    ++
Sbjct: 1048 YIASQGPLSNTCQDFWQMVWEQGVSIIAMVTAEEERGREKSFRYWPRLGSRHNTVTYGRF 1107

Query: 426  TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
             I   F + +  Y     L  K   T  +RTI+H  +T WPDH  P +    L  L ++ 
Sbjct: 1108 KITTRFRTESGCYATTG-LKIKHLLTGQERTIWHLQYTDWPDHGCPDDIKGFLTYLEEIQ 1166

Query: 486  YRLQQIMTGTDPP-AQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
               +   + +DP      V VHCSAG+GRTG  I+ ++++  +        +DI   +  
Sbjct: 1167 SVRRHTNSISDPKNTNLPVLVHCSAGVGRTGVVILSEILIACLEHNE---TLDIPNVLLK 1223

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
            +R QR  +VQ  AQY FIYM ++ ++   +
Sbjct: 1224 LRAQRMMVVQTFAQYSFIYMVLIHYLRNSR 1253



 Score = 34.7 bits (76), Expect = 7.1
 Identities = 14/43 (32%), Positives = 29/43 (67%), Gaps = 3/43 (6%)

Query: 225  KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
            +PE+  KNR+ +++P+D +RV   ++ P     + YINA++++
Sbjct: 999  QPESSDKNRFHDVLPYDSSRV---ELVPTKENNTGYINASHVK 1038


>UniRef50_Q24495 Cluster: Receptor protein tyrosine phosphatase; n=7;
            Sophophora|Rep: Receptor protein tyrosine phosphatase -
            Drosophila melanogaster (Fruit fly)
          Length = 1767

 Score =  128 bits (310), Expect = 3e-28
 Identities = 72/209 (34%), Positives = 110/209 (52%), Gaps = 14/209 (6%)

Query: 363  HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
            H   + +I TQG   +T   FW M W+ + R I+M T+  E+G+ KC++YWP        
Sbjct: 1392 HNSPREFIVTQGPFHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFY 1451

Query: 423  KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
                +    ++   D+++  F+V++  E+ + R   HFHFT WPD  VP  P  ++  + 
Sbjct: 1452 GDIKVQLIIDTHYHDWSISEFMVSRNCESRIMR---HFHFTTWPDFGVPEPPLSLVRFV- 1507

Query: 483  DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
                R  + + GTD      + VHCSAG+GR+GTFI +D IL  I K  +   +DI   V
Sbjct: 1508 ----RAFRDVIGTD---MRPIIVHCSAGVGRSGTFIALDRILQHIHKSDY---VDIFGIV 1557

Query: 543  QMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
              +R +R  MVQ E QY  I+  +L  +E
Sbjct: 1558 FAMRKERVFMVQTEQQYVCIHQCLLAVLE 1586



 Score = 51.2 bits (117), Expect = 8e-05
 Identities = 30/65 (46%), Positives = 39/65 (60%), Gaps = 4/65 (6%)

Query: 202  FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
            F EEFE L+ +   Q       + P N  KNR+ NI+P+DH+R  L+  P D   GSDYI
Sbjct: 1329 FSEEFEELKHVGRDQACSF--ANLPCNRPKNRFTNILPYDHSRFKLQ--PVDDDDGSDYI 1384

Query: 262  NANYI 266
            NANY+
Sbjct: 1385 NANYM 1389


>UniRef50_A7SMI6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 556

 Score =  128 bits (310), Expect = 3e-28
 Identities = 75/197 (38%), Positives = 101/197 (51%), Gaps = 13/197 (6%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
           YIA QG L+ TI  FW +IW++    I+M      + +  CERYWP+    E       +
Sbjct: 66  YIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDGHQEYGDVAVSV 125

Query: 429 NEFESSTPDYTLRRFLVTKK--DETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +    T D+T+R FLV  +   E   KR +  F FTAWPD  VP     ++       Y
Sbjct: 126 VDVTHMT-DWTVRTFLVWVRLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRY 184

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
            L    TG        + VHC AG+GRTGTFI ID ++DQ+  EG    +D++  V  +R
Sbjct: 185 HLSSEETGP-------ILVHCGAGVGRTGTFIAIDSLMDQMMMEGV---VDVYGFVAQMR 234

Query: 547 DQRSGMVQNEAQYKFIY 563
            QR+ MVQ   QY FIY
Sbjct: 235 TQRNFMVQTHEQYAFIY 251



 Score =  101 bits (241), Expect = 7e-20
 Identities = 65/208 (31%), Positives = 104/208 (50%), Gaps = 22/208 (10%)

Query: 365 YNKT--YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
           YN+   YIATQ  +  TI  FW M+W++    I+M T+  +RG+++ E YWP  +     
Sbjct: 356 YNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWP-RDGCVRY 414

Query: 423 KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
            KY +    E    D+T R       D   V    YHF +  W  H +P      +N L+
Sbjct: 415 GKYIVTKIDEEELDDHTQR-----SMDSLLV----YHFQYHNWSAHGMPPR----MNGLV 461

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
            ++ ++Q+I +  D        VHCS G GRTG F+ + + ++++  E     +DI +TV
Sbjct: 462 FLHEQVQKIQSTED---HGPTVVHCSDGAGRTGVFLALAISIERLEAED---TVDIFQTV 515

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
           + +R QR  +V +  QY   Y AV  ++
Sbjct: 516 RWLRSQRPALVGSIEQYSCCYQAVKSYL 543



 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 22/41 (53%), Positives = 29/41 (70%), Gaps = 2/41 (4%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           P N  KNRY NI+P+DH+RV+L+        GSDYINAN++
Sbjct: 19  PYNKTKNRYPNILPYDHSRVVLR--ARKDSHGSDYINANFV 57


>UniRef50_UPI00006A1133 Cluster: protein tyrosine phosphatase,
           non-receptor type 20; n=6; Tetrapoda|Rep: protein
           tyrosine phosphatase, non-receptor type 20 - Xenopus
           tropicalis
          Length = 275

 Score =  128 bits (309), Expect = 4e-28
 Identities = 76/200 (38%), Positives = 110/200 (55%), Gaps = 15/200 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKYTI 427
           YI TQG L  T+  FW M+W+    +IIM T+E E GKVK E+YWP+ + +T   +  ++
Sbjct: 80  YICTQGPLPDTVNYFWQMVWENHSSVIIMMTQERESGKVKSEQYWPEQIQETWKGENLSL 139

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
             E  ++  D+T+R   + +K ET   R I H  FT WPDH  P  P  +L+ L  +  R
Sbjct: 140 RLEKCNALQDFTIRIMTLFQK-ETGENRLITHLQFTTWPDHSTPQSPQSLLHFLCYLR-R 197

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                       +  + VHCSAGIGRTG  I + +IL  + ++G   +  I   V+ +R 
Sbjct: 198 FHN---------EWPLVVHCSAGIGRTGVLICVHVILTYL-EQGI--QFQIKDIVKTMRQ 245

Query: 548 QRSGMVQNEAQYKFIYMAVL 567
           QR GM+Q + QY F Y A+L
Sbjct: 246 QRYGMIQTKDQYIFCYKALL 265



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 8/43 (18%)

Query: 224 SKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           S PEN  KNRY++I+P+D TRV + D          YINA+Y+
Sbjct: 35  SAPENRNKNRYRDILPYDSTRVRVGD--------EGYINASYV 69


>UniRef50_UPI00004D876B Cluster: protein tyrosine phosphatase,
           non-receptor type 20; n=1; Xenopus tropicalis|Rep:
           protein tyrosine phosphatase, non-receptor type 20 -
           Xenopus tropicalis
          Length = 267

 Score =  128 bits (309), Expect = 4e-28
 Identities = 76/200 (38%), Positives = 110/200 (55%), Gaps = 15/200 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKYTI 427
           YI TQG L  T+  FW M+W+    +IIM T+E E GKVK E+YWP+ + +T   +  ++
Sbjct: 70  YICTQGPLPDTVNYFWQMVWENHSSVIIMMTQERESGKVKSEQYWPEQIQETWKGENLSL 129

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
             E  ++  D+T+R   + +K ET   R I H  FT WPDH  P  P  +L+ L  +  R
Sbjct: 130 RLEKCNALQDFTIRIMTLFQK-ETGENRLITHLQFTTWPDHSTPQSPQSLLHFLCYLR-R 187

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                       +  + VHCSAGIGRTG  I + +IL  + ++G   +  I   V+ +R 
Sbjct: 188 FHN---------EWPLVVHCSAGIGRTGVLICVHVILTYL-EQGI--QFQIKDIVKTMRQ 235

Query: 548 QRSGMVQNEAQYKFIYMAVL 567
           QR GM+Q + QY F Y A+L
Sbjct: 236 QRYGMIQTKDQYIFCYKALL 255


>UniRef50_UPI0000E4853E Cluster: PREDICTED: similar to Receptor-type
           tyrosine-protein phosphatase alpha precursor
           (Protein-tyrosine phosphatase alpha) (R-PTP-alpha); n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Receptor-type tyrosine-protein phosphatase alpha
           precursor (Protein-tyrosine phosphatase alpha)
           (R-PTP-alpha) - Strongylocentrotus purpuratus
          Length = 1344

 Score =  127 bits (306), Expect = 1e-27
 Identities = 80/206 (38%), Positives = 110/206 (53%), Gaps = 19/206 (9%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
           +K YIA+QG   T++  FW M+WQE+V  I M TK  E  K+KC +YWPD  K + V+  
Sbjct: 789 DKAYIASQGPNKTSMDDFWRMVWQENVTTIAMVTKLQEGDKIKCRQYWPD-RKGQSVEFG 847

Query: 426 TI---LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
           TI   L E E  T     RR ++ K +E+   R +  FHFT WPD  VP     +L  + 
Sbjct: 848 TIKVELMELEPCTGG-VARRMVMRKGEES---RRVTQFHFTEWPDKGVPKHTSSLLKFIK 903

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
           +V     Q    T P     + +HCSAG+GRTG    ID ++   ++      +D+   V
Sbjct: 904 EVKADHGQY---THP-----LIIHCSAGVGRTGVVTSIDSVVAHAKRTRM---VDVFNFV 952

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLE 568
             +R +R  MVQ + QY FIY AVLE
Sbjct: 953 TNMRQKRPYMVQTQEQYAFIYGAVLE 978



 Score =  100 bits (239), Expect = 1e-19
 Identities = 61/206 (29%), Positives = 99/206 (48%), Gaps = 12/206 (5%)

Query: 368  TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI 427
            T++ TQ  L  T+  FWSM+       I+M   + +  K  C +YWP+ +  +    Y++
Sbjct: 1076 TFMTTQMPLPATVSDFWSMVLNYKPSTIVMLNDKSQNDK-SCAQYWPNADSAQF-GSYSV 1133

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
                 S+  D T+R+  +T+  +T+   T Y FH   WP H    + G    I L     
Sbjct: 1134 TTLSTSTDGDMTIRKLKITRNSKTSHTVTQYQFH--GWPKHGSDQQSGARSLIKL----- 1186

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
            ++ +   T+   +  + VHC +G GRTG        + QI +      +DI +TV+ +R 
Sbjct: 1187 IRAVKGSTNKMNEFSILVHCLSGAGRTGVLCTAMECIAQIAERD---SVDIFQTVKTLRA 1243

Query: 548  QRSGMVQNEAQYKFIYMAVLEFIETE 573
             R   VQ E +Y FIY A+ E++ TE
Sbjct: 1244 DRMQFVQTEEEYAFIYDAIREYLHTE 1269



 Score = 48.0 bits (109), Expect = 7e-04
 Identities = 28/65 (43%), Positives = 38/65 (58%), Gaps = 5/65 (7%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F EEF  L   +   ++ +    +  N +KNRYKNI+P+D  RV L+ I  D  P SDY 
Sbjct: 724 FSEEFHDLPGPD---IYPQTVAREQINFKKNRYKNILPYDSARVKLEVI--DDIPHSDYF 778

Query: 262 NANYI 266
           NA+YI
Sbjct: 779 NASYI 783



 Score = 41.1 bits (92), Expect = 0.082
 Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 12/98 (12%)

Query: 171  TRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMM-ENLQLFDRMEGSKPENI 229
            T I V HF   ++ L    +G   S   K     EF+TL+ +  +        G  P+N 
Sbjct: 985  TLIPVIHFTDHLQDLHTSGDGRGRSKMTK-----EFQTLKSLCPDPPASQTRSGRTPDNQ 1039

Query: 230  RKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
             KNRY N +P    RVIL        P  DYINA+ ++
Sbjct: 1040 PKNRYGNNLPLQRNRVILDS------PDHDYINASQMK 1071


>UniRef50_UPI0000D578C4 Cluster: PREDICTED: similar to CG10975-PB,
            isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
            similar to CG10975-PB, isoform B - Tribolium castaneum
          Length = 1346

 Score =  126 bits (305), Expect = 1e-27
 Identities = 67/215 (31%), Positives = 111/215 (51%), Gaps = 14/215 (6%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKY 425
            K +I  QG + TT+  FW MIW++ + +I+M T   E  K KC +YWPD  +  +     
Sbjct: 855  KKFICAQGPMDTTVNDFWRMIWEQHLELILMLTNLEEYSKTKCAKYWPDKCDGDKCFGDI 914

Query: 426  TILNEFESSTPDYTLRRFLVTKK--DETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
            T+ +  E+   DY +R   +++    +   +R I  +H+  W D   P  P  ++  +  
Sbjct: 915  TVTHVQETRYSDYIVRELRISRNAPGKDKEERQITQYHYLVWKDFMAPEHPNGIIKFIKR 974

Query: 484  VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
            VN     I  G        + +HCSAG+GRTGT + +D +L Q+++E     + I  T+ 
Sbjct: 975  VN-EAYSIEKG-------CILIHCSAGVGRTGTLVALDCLLQQLKEEE---HVSIFNTIC 1023

Query: 544  MVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVG 578
             +R QR+ +VQ+  QY FIY A++E  +     +G
Sbjct: 1024 DLRHQRNFLVQSLKQYIFIYRALMEVAQYGDTEIG 1058



 Score = 98.7 bits (235), Expect = 4e-19
 Identities = 59/205 (28%), Positives = 103/205 (50%), Gaps = 13/205 (6%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            +++I TQ    +TI  FW MI ++ + +I+M +   E G+ KC RYWPD ++       T
Sbjct: 1149 ESFIITQDPTESTINDFWRMISEQGISVIVMLS---ELGEGKCPRYWPDEDEG-TYDHIT 1204

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +  E   S P YT R   +  +D     + + H  +  WP   V  E   V   L+++  
Sbjct: 1205 VRYEQAESCPYYTRREMYIKSRD--CDDQRVIHLQYHGWPT--VDGEVPEVTRGLIELVD 1260

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
              Q  +   D     VV  HCS G  R+  F+ + +++ Q+R E     +D+    + +R
Sbjct: 1261 HSQASLVHNDCSPSMVV--HCSLGSDRSSMFVGLTILVQQLRTEK---RVDVFTVTRKLR 1315

Query: 547  DQRSGMVQNEAQYKFIYMAVLEFIE 571
             QR+G++ + AQY+F++ A++ + E
Sbjct: 1316 SQRNGLINSYAQYEFLHRAIVNYAE 1340



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 27/66 (40%), Positives = 35/66 (53%), Gaps = 4/66 (6%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
           GF +EFE L   +             EN+ KNRY +I  +D TRV L  I  D   GSDY
Sbjct: 787 GFQQEFELLP--DRFSDRTTRASDARENVYKNRYPDIKAYDQTRVKLSQI--DSIAGSDY 842

Query: 261 INANYI 266
           +NAN++
Sbjct: 843 VNANFV 848



 Score = 39.9 bits (89), Expect = 0.19
 Identities = 31/80 (38%), Positives = 42/80 (52%), Gaps = 6/80 (7%)

Query: 204  EEFET-LQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYIN 262
            EEFE  L   E+ +     +G   EN  KNR   +IP+D  RVIL   P  G   S YIN
Sbjct: 1083 EEFENILNAFEDRKSCSVAKGD--ENREKNRSDVVIPYDRNRVIL--TPLSGKEHSTYIN 1138

Query: 263  ANYIR-CDSMDSISDSQEFT 281
            A++I   D+ +S   +Q+ T
Sbjct: 1139 ASFIEGYDNTESFIITQDPT 1158


>UniRef50_A6NJM5 Cluster: Uncharacterized protein PTPRN2; n=9;
           Eutheria|Rep: Uncharacterized protein PTPRN2 - Homo
           sapiens (Human)
          Length = 986

 Score =  126 bits (305), Expect = 1e-27
 Identities = 74/204 (36%), Positives = 110/204 (53%), Gaps = 13/204 (6%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKK 424
           N  YIATQG L  T+  FW M+W+    +I+M T   E G  +C  YWPD       + +
Sbjct: 784 NPAYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGSNLYHIYE 843

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
             +++E      D+ +R F + K  +T   RT+  FHF +W D  VPS        LLD 
Sbjct: 844 VNLVSE-HIWCEDFLVRSFYL-KNLQTNETRTVTQFHFLSWYDRGVPSSS----RSLLDF 897

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
             ++ +   G   P   ++C  C  G GR+GT+++IDM+L+++ K     EIDI  T++ 
Sbjct: 898 RRKVNKCYRGRSCP--IILC--CGDGAGRSGTYVLIDMVLNKMAKGA--KEIDIAATLEH 951

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLE 568
           +RDQR GMVQ + Q++F   AV E
Sbjct: 952 LRDQRPGMVQTKEQFEFALTAVAE 975



 Score = 35.9 bits (79), Expect = 3.1
 Identities = 18/42 (42%), Positives = 27/42 (64%), Gaps = 2/42 (4%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           + EN+ KNR   ++ +DH+RV+LK    +    SDYINA+ I
Sbjct: 738 REENVPKNRSLAVLTYDHSRVLLK--AENSHSHSDYINASPI 777


>UniRef50_P29074 Cluster: Tyrosine-protein phosphatase non-receptor
           type 4; n=77; Euteleostomi|Rep: Tyrosine-protein
           phosphatase non-receptor type 4 - Homo sapiens (Human)
          Length = 926

 Score =  126 bits (305), Expect = 1e-27
 Identities = 76/236 (32%), Positives = 117/236 (49%), Gaps = 19/236 (8%)

Query: 336 VLRPNPNYFNTTIPKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRII 395
           +L+ N +Y N      A      +P+  + N+ YIA QG L  T   FW M W++   ++
Sbjct: 697 ILKGNEDYIN------ANYINMEIPSSSIINQ-YIACQGPLPHTCTDFWQMTWEQGSSMV 749

Query: 396 IMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKR 455
           +M T ++ERG+VKC +YWP+   +     Y +    E     Y  R+  +  + E    R
Sbjct: 750 VMLTTQVERGRVKCHQYWPEPTGSSSYGCYQVTCHSEEGNTAYIFRKMTLFNQ-EKNESR 808

Query: 456 TIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTG 515
            +    + AWPDH VP +    L+ +  V  +      G + P    V VHCSAGIGRTG
Sbjct: 809 PLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNK----RAGKEEP----VVVHCSAGIGRTG 860

Query: 516 TFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
             I ++  +  I        +DI RT   +RDQR+ M+Q  +QY+F+  A+L+  E
Sbjct: 861 VLITMETAMCLIECNQPVYPLDIVRT---MRDQRAMMIQTPSQYRFVCEAILKVYE 913



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 24/44 (54%), Positives = 29/44 (65%), Gaps = 7/44 (15%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           P+NI KNRY++I P+D TRVILK          DYINANYI  +
Sbjct: 677 PQNISKNRYRDISPYDATRVILKG-------NEDYINANYINME 713


>UniRef50_Q4SSV8 Cluster: Chromosome undetermined SCAF14347, whole
           genome shotgun sequence; n=3; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14347, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 767

 Score =  126 bits (304), Expect = 2e-27
 Identities = 76/208 (36%), Positives = 115/208 (55%), Gaps = 14/208 (6%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           + Y+A QG L +    FW MIWQ++V +++M T   E+G+ KCE+YWP   + E    Y 
Sbjct: 218 RAYVAAQGPLRSGREDFWRMIWQQNVGVVVMITNLKEKGRTKCEQYWPGEGQ-EDYGPYQ 276

Query: 427 ILNEFESSTPDYTLRRFLVT----KKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
           +  +   +   YTLR   V+    K  +  V+ T+ H+H+T WPD  VP     VL+ + 
Sbjct: 277 VTLKSTLTLAYYTLRTLSVSDTANKASQKRVEHTVLHYHYTQWPDMGVPEYTLPVLSFIR 336

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
             +    Q M   D        V  SAG+GRTGT+IVID +L QI+ +G    +++   +
Sbjct: 337 ASSRARTQEMGPGD------YGVFDSAGVGRTGTYIVIDSMLQQIQDQG---TVNVLGFL 387

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
           + VR QR+ +VQ E QY FI+ A++E I
Sbjct: 388 KHVRTQRNFLVQTEEQYVFIHDALVEAI 415



 Score = 35.9 bits (79), Expect = 3.1
 Identities = 30/81 (37%), Positives = 42/81 (51%), Gaps = 17/81 (20%)

Query: 202 FWEEFETLQMMENLQLFDRMEG------SKPENIRKNRYKNII---------PFDHTRVI 246
           F +EFE  Q   ++Q+     G      + P+N  KNRY NI+         P DH+RV 
Sbjct: 132 FSKEFEVNQAFGDVQVCTVDMGITADSSNHPDNKSKNRYINILACEWLFPCDPHDHSRVK 191

Query: 247 LKD-IPPDGPPGSDYINANYI 266
           L + +  DG  G DYINAN++
Sbjct: 192 LSNSLDRDGKCG-DYINANFV 211


>UniRef50_A7RUW8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 883

 Score =  126 bits (304), Expect = 2e-27
 Identities = 74/210 (35%), Positives = 108/210 (51%), Gaps = 15/210 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
           YIA QG L  T   FW MIW+++  ++IM T  +ERG+VKC +YWP+   T       ++
Sbjct: 682 YIAAQGPLEKTCGDFWQMIWEQESTLVIMLTTTMERGRVKCHQYWPEGEDTWTFGNLEVV 741

Query: 429 -NEFESSTPDYTLRRFLVTKKDETTVK-RTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            N+    +P Y  R   VT  D TT++ R I    + AWPDH VP +    L  +  V +
Sbjct: 742 CNKIRDFSPSYVYREMYVT--DTTTLRSRVIIQLQYLAWPDHDVPDDATDFLEFVHSVRH 799

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
             +    GT  PA     VHCSAG+GR+G  + I+     I  EG +    +   V+ +R
Sbjct: 800 YRE----GTSTPA----VVHCSAGVGRSGVLMFIETAFGMI--EGAEPVYPL-ELVRRMR 848

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIETEKQR 576
           DQR  ++Q   Q+ F+  A L+  + E  R
Sbjct: 849 DQRGSLIQTPGQFLFVCEATLKAYDDEVVR 878



 Score = 48.4 bits (110), Expect = 5e-04
 Identities = 23/48 (47%), Positives = 32/48 (66%), Gaps = 7/48 (14%)

Query: 222 EGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           +  KPEN+ KNRY++I+P+D TRV L         GSDYINAN++  +
Sbjct: 632 DARKPENLPKNRYRDILPYDETRVKLF-------KGSDYINANFVNME 672


>UniRef50_P70289 Cluster: Receptor-type tyrosine-protein phosphatase V
            precursor; n=8; Eutheria|Rep: Receptor-type
            tyrosine-protein phosphatase V precursor - Mus musculus
            (Mouse)
          Length = 1705

 Score =  126 bits (304), Expect = 2e-27
 Identities = 76/223 (34%), Positives = 116/223 (52%), Gaps = 13/223 (5%)

Query: 349  PKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVK 408
            P S     N +P  + + +  IATQG L  T+  FW ++W++ V +IIM T  +E G+V 
Sbjct: 1200 PHSDYINANFIPG-YSHPQEIIATQGPLKKTVEDFWRLVWEQQVHVIIMLTVGMENGRVL 1258

Query: 409  CERYWPDLNKTEVVKKYTILNEF-ESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPD 467
            CE YWP +N T V   +   +   E S  ++T R F +    E   +R +    FT WPD
Sbjct: 1259 CEHYWP-VNSTPVTHGHITTHLLAEESEDEWTRREFQLQHGAEQK-QRRVKQLQFTTWPD 1316

Query: 468  HRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQI 527
            H VP  P  +L  +  V   ++    G  P     + VHCSAG+GRTGTF+ +   + Q+
Sbjct: 1317 HSVPEAPSSLLAFVELVQEEVKATQ-GKGP-----ILVHCSAGVGRTGTFVALLPAVRQL 1370

Query: 528  RKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
             +E     +D+  TV ++R  R  M+Q  +QY F++  +L  I
Sbjct: 1371 EEEQV---VDVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKI 1410



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 32/67 (47%), Positives = 44/67 (65%), Gaps = 4/67 (5%)

Query: 200  QGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSD 259
            Q F++EFE L+ +   Q   R+E   P NI KNRY +++P+DH+RV L  +   G P SD
Sbjct: 1148 QAFFQEFEELKEVGKDQ--PRLEAEHPANITKNRYPHVLPYDHSRVRLTQL--SGEPHSD 1203

Query: 260  YINANYI 266
            YINAN+I
Sbjct: 1204 YINANFI 1210


>UniRef50_Q98936 Cluster: Receptor-type tyrosine-protein phosphatase
            gamma precursor; n=9; Amniota|Rep: Receptor-type
            tyrosine-protein phosphatase gamma precursor - Gallus
            gallus (Chicken)
          Length = 1422

 Score =  126 bits (304), Expect = 2e-27
 Identities = 77/213 (36%), Positives = 113/213 (53%), Gaps = 20/213 (9%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTE-----V 421
            K YIATQG L +T   FW MIW +   II+M T  +E+G+ KC++YWP  N  E     V
Sbjct: 896  KAYIATQGPLKSTFEDFWRMIWAQHTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIV 955

Query: 422  VKKYTILNEFESSTP----DYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRV 477
              K T ++   +  P    ++   +    K      +RT+  +H+T WPD  VP     V
Sbjct: 956  TLKSTNIHACYTVRPLHGQEHKDEKGSERKPKGRQNERTVIQYHYTQWPDMGVPEYALPV 1015

Query: 478  LNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEID 537
            L  +        +  +    P    V VHCSAG+GRTGT+IVID +L QI+ +     ++
Sbjct: 1016 LTFV--------RRSSAARTPHMGPVVVHCSAGVGRTGTYIVIDSMLQQIKDKS---TVN 1064

Query: 538  IHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
            +   ++ +R QR+ +VQ E QY FI+ A+LE I
Sbjct: 1065 VLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAI 1097



 Score = 59.7 bits (138), Expect = 2e-07
 Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 9/100 (9%)

Query: 167 PFNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKP 226
           P +   I V+ F   + +L   N+          GF E+FE +Q             + P
Sbjct: 799 PDDMEAIPVKQFVKHISELYSNNQ---------HGFSEDFEEVQRCTADMNITAEHSNHP 849

Query: 227 ENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           +N  KNRY NI+ +DH+RV L+ +P      SDYINANY+
Sbjct: 850 DNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYV 889



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 47/217 (21%), Positives = 89/217 (41%), Gaps = 22/217 (10%)

Query: 370  IATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL- 428
            + TQ  L  T   FW MIW  + +II+M        + +   YWP   ++   + +T+  
Sbjct: 1198 VITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFV-YWPSREESMNCEAFTVTL 1256

Query: 429  ---NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVP-SEPGRVLNILLDV 484
               +    S  +  +    + +  +      + HF    WP+   P S    ++N++ + 
Sbjct: 1257 ISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKE- 1315

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
                 + +T   P       VH   G    GT   +  +  Q+  E     +D+ +  +M
Sbjct: 1316 -----EALTRDGP-----TIVHDEYGAVSAGTLCALTTLSQQLENEN---AVDVFQVAKM 1362

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGP 581
            +   R G+  +  QY+F+Y A+L  + T++   G GP
Sbjct: 1363 INLMRPGVFTDIEQYQFLYKAMLSLVSTKEN--GNGP 1397



 Score = 38.7 bits (86), Expect = 0.44
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 2/53 (3%)

Query: 214  NLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            N +  +     K  N  KNR  +++P +  RV L  +P  G  G+DYINA+YI
Sbjct: 1138 NAKYVECFSAQKDCNKEKNRNSSVVPSERARVGLAPLP--GMKGTDYINASYI 1188


>UniRef50_Q6IPX8 Cluster: PTPN22 protein; n=5; Catarrhini|Rep:
           PTPN22 protein - Homo sapiens (Human)
          Length = 752

 Score =  126 bits (303), Expect = 2e-27
 Identities = 68/156 (43%), Positives = 85/156 (54%), Gaps = 12/156 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKKY 425
           K YIATQG LSTT+  FW MIW+  V II+M   E E GK KCERYW +  + ++    +
Sbjct: 97  KAYIATQGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPF 156

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
           ++  E E    DY +R   V    ET   RTIY FH+  WPDH VPS    +L ++ DV 
Sbjct: 157 SVSCEAEKRKSDYIIRTLKVKFNSET---RTIYQFHYKNWPDHDVPSSIDPILELIWDV- 212

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVID 521
            R  Q            +C+HCSAG GRTG    ID
Sbjct: 213 -RCYQ------EDDSVPICIHCSAGCGRTGVICAID 241



 Score = 51.6 bits (118), Expect = 6e-05
 Identities = 24/43 (55%), Positives = 33/43 (76%), Gaps = 2/43 (4%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           KP+NI+KNRYK+I+P+D++RV L  I  D    S YINAN+I+
Sbjct: 51  KPKNIKKNRYKDILPYDYSRVELSLITSD--EDSSYINANFIK 91


>UniRef50_Q99952 Cluster: Tyrosine-protein phosphatase non-receptor
           type 18; n=18; Eutheria|Rep: Tyrosine-protein
           phosphatase non-receptor type 18 - Homo sapiens (Human)
          Length = 458

 Score =  126 bits (303), Expect = 2e-27
 Identities = 70/201 (34%), Positives = 107/201 (53%), Gaps = 12/201 (5%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI- 427
           YIATQG L  T+  FW ++W+  V++I+M  +EIE G+ +CERYW    +      + I 
Sbjct: 101 YIATQGPLPHTLLDFWRLVWEFGVKVILMACREIENGRKRCERYWAQEQEPLQTGLFCIT 160

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
           L + +    D  LR   VT + E+   R++Y   + +WPD  VPS P  +L ++ +   R
Sbjct: 161 LIKEKWLNEDIMLRTLKVTFQKES---RSVYQLQYMSWPDRGVPSSPDHMLAMVEEAR-R 216

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
           LQ   +G +P     +CVHCSAG GRTG    +D +   +  +    +  +   V  +R 
Sbjct: 217 LQG--SGPEP-----LCVHCSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRK 269

Query: 548 QRSGMVQNEAQYKFIYMAVLE 568
           QR   VQ E QY+F+Y  V +
Sbjct: 270 QRPAAVQTEEQYRFLYHTVAQ 290



 Score = 62.1 bits (144), Expect = 4e-08
 Identities = 27/45 (60%), Positives = 36/45 (80%), Gaps = 2/45 (4%)

Query: 223 GSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           GS+PEN+RKNRYK+++P+D TRVIL  +  +G   SDYIN N+IR
Sbjct: 51  GSRPENVRKNRYKDVLPYDQTRVILSLLQEEG--HSDYINGNFIR 93


>UniRef50_Q4TC72 Cluster: Chromosome undetermined SCAF7048, whole
            genome shotgun sequence; n=3; root|Rep: Chromosome
            undetermined SCAF7048, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 1991

 Score =  125 bits (302), Expect = 3e-27
 Identities = 69/212 (32%), Positives = 103/212 (48%), Gaps = 18/212 (8%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            Y + Y   QG L  T   FW M+W+  V  ++M         VKC++YWP   +      
Sbjct: 1778 YRREYNPAQGPLPGTKDDFWRMVWEHGVCNVVM---------VKCDQYWPPDAEPLYYGD 1828

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
              I    ES  P++T+R F ++ +      R + HFH+T WPDH VP     ++     V
Sbjct: 1829 LVIQKLSESVLPEWTIREFRISSESGCAQPRRLRHFHYTVWPDHGVPESTQSLVQFTRTV 1888

Query: 485  NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
               + +       P+     VHCSAG+GRTGTFI +D +L Q+  +G    +D++  V  
Sbjct: 1889 RDYVDR------SPSTGATVVHCSAGVGRTGTFIALDRVLQQLDAKG---TVDLYSCVFD 1939

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQR 576
            +R  R  MVQ E QY F++  V + +   K R
Sbjct: 1940 MRLHRQHMVQTEGQYTFLHQCVRDVLRARKHR 1971



 Score = 54.0 bits (124), Expect = 1e-05
 Identities = 31/63 (49%), Positives = 38/63 (60%), Gaps = 4/63 (6%)

Query: 204  EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
            EEFE L+ +   Q  D      PEN  KNRY NI+P+D TRV L  +  D  P SDYINA
Sbjct: 1715 EEFEDLKDVGRNQAMD--VARVPENRGKNRYNNILPYDSTRVKLSYLEDD--PCSDYINA 1770

Query: 264  NYI 266
            +Y+
Sbjct: 1771 SYV 1773


>UniRef50_Q4T7R9 Cluster: Chromosome undetermined SCAF8020, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF8020,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 771

 Score =  125 bits (302), Expect = 3e-27
 Identities = 81/225 (36%), Positives = 116/225 (51%), Gaps = 24/225 (10%)

Query: 365 YNK--TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKV-KCERYWPDLNKTEV 421
           YNK   YIA QG L +T   FW M+W+++  +I+M T  +E+G+V KCE+YWP     E 
Sbjct: 161 YNKPRAYIAAQGPLRSTFKDFWRMVWEQNTGVIVMITNLMEKGRVRKCEQYWPAEGSEEH 220

Query: 422 VKKYTILNEFESSTPDYTLRRFLVTK---------KDETTVKRTIYHFHFTAWPDHRVPS 472
                 L   E     YT+R F + K         K  T  +RT+  +H+T WPD  VP 
Sbjct: 221 GDVVVTLKSTEVHA-CYTVRWFSLCKVKKTGKGSHKSRTQSERTVLQYHYTQWPDMGVPE 279

Query: 473 EPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGF 532
               VL  +        +  +    P    + VHCSAG+GRTGT+IVID +L QI +   
Sbjct: 280 YTLPVLTFV--------RRSSAAQTPDMGPMIVHCSAGVGRTGTYIVIDSMLKQIEERK- 330

Query: 533 DCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
              ++I   ++ +R QR+ +VQ E QY FI+  + E I  +K  V
Sbjct: 331 --TVNILGFLKHIRRQRNYLVQTEEQYVFIHDVLTEAILGKKTEV 373



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 34/101 (33%), Positives = 56/101 (55%), Gaps = 4/101 (3%)

Query: 182 VKQLQKENEGPIESMAYKQGFWEEFETLQMME-NLQLFDRMEGSKPENIRKNRYKNIIPF 240
           VKQ  +   G   S  +++GF E+FE +Q    N++L      + P+N  +NRY NI+ +
Sbjct: 45  VKQFIRHISGRRSS--HQRGFSEDFEEVQRCTANMKLTSECS-NHPDNKHRNRYVNIMAY 101

Query: 241 DHTRVILKDIPPDGPPGSDYINANYIRCDSMDSISDSQEFT 281
           DH+RV L+ +       SDYINAN++   +   +S S+  +
Sbjct: 102 DHSRVKLQPLEGKDSKYSDYINANHVDVSAAGVLSISRSLS 142


>UniRef50_UPI0000E816A0 Cluster: PREDICTED: similar to
            protein-tyrosine-phosphatase (EC 3.1.3.48), receptor type
            OST precursor - rat; n=2; Gallus gallus|Rep: PREDICTED:
            similar to protein-tyrosine-phosphatase (EC 3.1.3.48),
            receptor type OST precursor - rat - Gallus gallus
          Length = 2269

 Score =  125 bits (301), Expect = 4e-27
 Identities = 75/221 (33%), Positives = 116/221 (52%), Gaps = 13/221 (5%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            +I TQG L  TI  FW ++W+++V  IIM T  +E G+V C+ YWP         +  + 
Sbjct: 1779 FIVTQGPLKKTIEDFWRLVWEQNVCNIIMLTVCMENGRVLCDHYWPSEAAPVSYGQVRVH 1838

Query: 429  NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
               +SS  ++T+R F +        +R + H H+TAWPDH +P     +L     V    
Sbjct: 1839 LLSQSSAEEWTMREFKLW--HGLRAERHVSHLHYTAWPDHGIPESTSSILAFRELVR--- 1893

Query: 489  QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
            + I +  D        VHCSAG+GR+GTFI +D +L Q+++E     +D+   V  +R  
Sbjct: 1894 EHIQSAKD---AGPTLVHCSAGVGRSGTFIALDRLLQQMKQEKV---VDMFGVVYTLRMN 1947

Query: 549  RSGMVQNEAQYKFIYMAVLEFIETEKQRVGL-GPEAAQDSP 588
            R  M+Q  +QY F++  +LE I  E+  +GL G E +   P
Sbjct: 1948 RYQMIQTLSQYIFLHSCILEKI-LEEPLLGLSGTETSCPIP 1987



 Score = 65.7 bits (153), Expect = 3e-09
 Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 14/211 (6%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
            ++ Y+A QG    T   FW+++W++D+  I+      E G+V  +  WP    +   K  
Sbjct: 2071 SRDYLAVQGPDKLTTEDFWTLVWEQDIHTILTLLPWQEMGEVPHDTCWPLEGDSLCTKLL 2130

Query: 426  TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            TI    E     +   + L  K ++   +R +  F +  W   + P+    V   LL   
Sbjct: 2131 TIQCGTEKPASGWRCIQ-LKVKHEKKGKERQVQQFLYRLWSSEKQPNVQSLV--ELLTAV 2187

Query: 486  YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHR-TVQM 544
             R         P     + +HCS G  + GT I +D +L Q++ E     +DI+  T+Q+
Sbjct: 2188 RRCVPNRKRAGP-----LLLHCSGGENQMGTLIALDCLLHQLKTER---TVDIYGVTLQL 2239

Query: 545  VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQ 575
            +R     M     QY F+Y  + + I T+KQ
Sbjct: 2240 MR-SCCLMTPTLDQYVFLYTCIRDII-TQKQ 2268



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 4/100 (4%)

Query: 167  PFNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKP 226
            P       +R+ H  +     +    +++ +    F++EFE L+ +   QL  ++    P
Sbjct: 1675 PQEMVTYSLRNVHRPIPIQNFKQYYEVKTASGNHAFFQEFEELKEVGKEQL--KVGAELP 1732

Query: 227  ENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
             N+ KNRY +++P+DH+RV L  +  D    SDYINAN++
Sbjct: 1733 ANVSKNRYPHVLPYDHSRVRLSQLGDD--LHSDYINANFV 1770


>UniRef50_UPI000069DA70 Cluster: Protein tyrosine phosphatase RQ; n=1;
            Xenopus tropicalis|Rep: Protein tyrosine phosphatase RQ -
            Xenopus tropicalis
          Length = 1242

 Score =  125 bits (301), Expect = 4e-27
 Identities = 65/206 (31%), Positives = 110/206 (53%), Gaps = 15/206 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK-TEVVKKYTI 427
            +IATQG L+ T+  FW M+W+   + I+M T+  E+G+++C +YWP+ NK   V     I
Sbjct: 1019 FIATQGPLAGTVGDFWRMVWETRAKTIVMLTQCYEKGRIRCHQYWPEDNKPVTVFGDIVI 1078

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
                E    D+T R   V +  +  + R     ++T+WP+H VP     +++ +      
Sbjct: 1079 TKVAEDVQIDWTTRDLKVERHGDFMIVR---QCNYTSWPEHGVPESTASLMHFV------ 1129

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
              +++    P       VHCSAG+GRTG F+ +D ++  I    F   +DI+  V  +R 
Sbjct: 1130 --KMIRANRPHENTPTVVHCSAGVGRTGVFVALDHLVQHINHHDF---VDIYGLVAELRS 1184

Query: 548  QRSGMVQNEAQYKFIYMAVLEFIETE 573
            +R  MVQN AQY F++  V++ + ++
Sbjct: 1185 ERMCMVQNMAQYIFLHQCVVDLLASK 1210



 Score = 48.4 bits (110), Expect = 5e-04
 Identities = 28/65 (43%), Positives = 38/65 (58%), Gaps = 5/65 (7%)

Query: 202  FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
            F EEF  + + + L + D      P N  KNR+ NI P+++ RV L  I   G PGSDYI
Sbjct: 951  FQEEFSIVMLNQYLAVSD---ADLPWNRSKNRFTNIKPYNNNRVKL--IADAGVPGSDYI 1005

Query: 262  NANYI 266
            NA+Y+
Sbjct: 1006 NASYV 1010


>UniRef50_Q8AV93 Cluster: CD45 protein tyrosine phosphatase receptor
           type C; n=2; Petromyzon marinus|Rep: CD45 protein
           tyrosine phosphatase receptor type C - Petromyzon
           marinus (Sea lamprey)
          Length = 1000

 Score =  125 bits (301), Expect = 4e-27
 Identities = 76/208 (36%), Positives = 110/208 (52%), Gaps = 15/208 (7%)

Query: 365 YNKT--YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTE-V 421
           YN +  YIA QG L  T   FW MIW++   +I+M TK  E GKVKC +YWP  ++ +  
Sbjct: 465 YNSSIRYIAAQGPLENTAGDFWQMIWEKKSSVIVMVTKCEEMGKVKCFQYWPHPDEDKRA 524

Query: 422 VKKYTILNEFESSTPDYTLRRFLVT-KKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNI 480
               T+    E    D  +R   ++  K        + H    +WPDH VP +P    N+
Sbjct: 525 YGDVTVTIMDEKPYADIVIRTLSISHSKHRGFGAHWVTHVQLVSWPDHGVPEDP----NL 580

Query: 481 LLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHR 540
           LL +  R+     G    A   V VHCSAG+GR+GT+I +D ++ Q+  EG    +D++ 
Sbjct: 581 LLKLRRRVNS-FNGAGCTA---VVVHCSAGVGRSGTYIGLDCLVRQLENEG---HVDVYG 633

Query: 541 TVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
            V  +R QR  MVQ E+QY  ++ A+LE
Sbjct: 634 CVFRLRHQRPLMVQVESQYVLLHRALLE 661



 Score = 84.2 bits (199), Expect = 9e-15
 Identities = 59/206 (28%), Positives = 100/206 (48%), Gaps = 13/206 (6%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           K+ IATQ  L  T+  FW M+ Q++   I+M ++  E GK +   YWP +  T+      
Sbjct: 781 KSIIATQNPLPDTVSDFWLMVVQQNCNHIVMLSELSEGGKEQSAHYWP-VKGTQNYGAVG 839

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           +  +  +S  D  +R   +T +++ +V   I + H   W    +P  P  +++I+  V  
Sbjct: 840 VTVKNVTSRRDLVVRELSLTYENKESVVTQIQYPH---WKPDGLPKSPKALVSIMNAV-- 894

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
           +  Q   G        + VHCS G  RTGTF  +   L+  R EG    +D  + V+ + 
Sbjct: 895 QGWQKENGN----HRHIVVHCSDGASRTGTFCALWNTLEAARIEGM---VDFFQAVKWLN 947

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIET 572
            QR  +V+N+  Y+F+Y  V  F+ +
Sbjct: 948 MQRPEIVKNKVHYRFLYETVCSFVNS 973



 Score = 48.0 bits (109), Expect = 7e-04
 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 7/65 (10%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F EEF        +  + + E ++  N +KNRY +I+P+DH RV L      G   SDYI
Sbjct: 405 FQEEFSNFP--RKINKYSQQEATQEYNTKKNRYSDILPYDHNRVKL-----SGEGESDYI 457

Query: 262 NANYI 266
           NA+Y+
Sbjct: 458 NASYV 462



 Score = 34.7 bits (76), Expect = 7.1
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 7/80 (8%)

Query: 168 FNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPE 227
           F  T + +   H+RV+ ++ +     ES         EF+ L   E    F +  G    
Sbjct: 665 FGNTELSMAKLHSRVQGMKFKGSQQDESPVDV-----EFKRLPTFEGT--FAQRAGRNSN 717

Query: 228 NIRKNRYKNIIPFDHTRVIL 247
           N+ KNR  N+IP+D  RV L
Sbjct: 718 NVNKNRSTNVIPYDFNRVKL 737


>UniRef50_Q4SWB8 Cluster: Chromosome undetermined SCAF13636, whole
            genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF13636, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1455

 Score =  125 bits (301), Expect = 4e-27
 Identities = 76/226 (33%), Positives = 119/226 (52%), Gaps = 27/226 (11%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YIATQG L  T   FW+M+ Q+   +I+M T+  ER +VKC+ YWP  ++     + ++ 
Sbjct: 1227 YIATQGPLPETRNDFWTMVLQQKASLIVMLTQCNERRRVKCDHYWPFTDEPVTYGEISVE 1286

Query: 429  NEFESSTPDYTLRRFLV------------------TKKDETTVKRTIYHFHFTAWPDHRV 470
               ES +P++T+R+F +                      +    R + H ++T+WPDH V
Sbjct: 1287 MLSESESPEWTVRKFRLGYVSTAVPSPPLLEAPPTPGPPQADNSRDVLHLNYTSWPDHGV 1346

Query: 471  PSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKE 530
            P+    + +IL  V+   QQ     +P     + VHCSAG+GRTGTFI +D ++  IR+ 
Sbjct: 1347 PTV-NAIESILQFVHIVRQQANRTKEP-----IVVHCSAGVGRTGTFIALDRLMQHIREH 1400

Query: 531  GFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQR 576
             F   +D+   V  +R  R  MVQ E QY FI+  VL   + ++Q+
Sbjct: 1401 EF---VDVLGMVSEMRSHRLSMVQTEEQYVFIHQCVLLMWQKKQQQ 1443



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 42/123 (34%), Positives = 64/123 (52%), Gaps = 19/123 (15%)

Query: 144  SLIEYYRSFPMVETTGEVLRLIQPFNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFW 203
            SL+ +Y + P  +T+ +  +L  P     +Q+  F    K++ K++       AYK  F 
Sbjct: 1089 SLLAFYIN-PWSKTSLKKRKLTSP-----VQLDDFDAYFKEMSKDS-------AYK--FS 1133

Query: 204  EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
             +FE L+ +  L L        P N  KNRY NI+P+D +RV L  +  D   G+DYINA
Sbjct: 1134 LQFEELKSV-GLDL-PHEAADLPVNRAKNRYTNILPYDFSRVKLVSLHND--DGADYINA 1189

Query: 264  NYI 266
            N+I
Sbjct: 1190 NFI 1192


>UniRef50_Q9NL16 Cluster: AmPTP10 protein; n=1; Branchiostoma
           belcheri|Rep: AmPTP10 protein - Branchiostoma belcheri
           (Amphioxus)
          Length = 480

 Score =  125 bits (301), Expect = 4e-27
 Identities = 75/185 (40%), Positives = 98/185 (52%), Gaps = 17/185 (9%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWPDLNKT--EVVKKY---TILNEFESSTPDYTLRRF 443
           QE    ++M T  +E G+ KCERYWP+ N      V+ Y   T+  E  S+  DY LR  
Sbjct: 1   QERSACVVMVTNLVENGRAKCERYWPEENSEYENNVQTYGDITVTAEKVSTMADYALRLL 60

Query: 444 LVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVV 503
            + K     V R + HF +T+WPD+ VP  P   +N +  V      I  G  P      
Sbjct: 61  HIQKAGVDEV-REVLHFQYTSWPDYGVPKHPTSTINFVKRVK---ASIPRGAGP-----T 111

Query: 504 CVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIY 563
            VHCSAG+GR+GTFI I  +LD I +EG    I+IH  V  +R+ R  MVQ   QY FIY
Sbjct: 112 IVHCSAGVGRSGTFITIAAMLDMIEEEG---AINIHDFVDAMRENRMTMVQTSDQYAFIY 168

Query: 564 MAVLE 568
            A+LE
Sbjct: 169 TALLE 173



 Score = 84.6 bits (200), Expect = 7e-15
 Identities = 59/204 (28%), Positives = 96/204 (47%), Gaps = 14/204 (6%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
           ++ TQ  L  T+  FW M+       +IM  +   + K    +YWPD   ++      + 
Sbjct: 279 FLVTQSPLPGTVTDFWRMLSDHRSVSVIMLNQLNPKDK-SVVKYWPD-EGSKTFGNLEVE 336

Query: 429 NEFESSTPDYTLRRFLVTKKDETTVKRTIYH-FHFTAWPDHR-VPSEPGRVLNILLDVNY 486
              ES     T+R+F ++       +  I H F FTAWP  R  P+    +L +L  V  
Sbjct: 337 MVSESREKSATVRQFKLSSDTRFDRQSDIVHQFEFTAWPSGRSTPTSVDDLLELLGLVEK 396

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
             QQ  +G  P     + VHC  G+GR+G F     +LD+++ E     +D+ + V+ +R
Sbjct: 397 WQQQ--SGNGP-----ITVHCINGVGRSGVFCTAHAMLDRLKTEQV---VDVFQAVKTLR 446

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFI 570
           + R  MV+ E QY+F Y   L ++
Sbjct: 447 NHRPNMVETEEQYQFCYQVALAYL 470



 Score = 40.3 bits (90), Expect = 0.14
 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 7/97 (7%)

Query: 171 TRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGS-KPENI 229
           T I    F  R   L ++N  P   +     + EEF+ L  +      D+   +  P N 
Sbjct: 180 TTIPADEFRDRFSTLSRKN--PKTGL---NAYQEEFKRLARVCPPLTPDKTRSALSPANK 234

Query: 230 RKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            KNR+ +++  D  R +L   P D PP +DYINA+++
Sbjct: 235 NKNRFSSVLASDSNRPMLTPRPGD-PPDADYINADFL 270


>UniRef50_A7RLA3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 489

 Score =  125 bits (301), Expect = 4e-27
 Identities = 77/195 (39%), Positives = 104/195 (53%), Gaps = 23/195 (11%)

Query: 386 MIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLV 445
           M+WQE   +I+M T  IE  K KC +YWPD N+ +   +YT+      +  DYT+R FLV
Sbjct: 1   MVWQERCSVIVMLTGLIEGSKEKCHKYWPDTNQPKPYGQYTVSLCKNEAFADYTVRTFLV 60

Query: 446 TKK-------DE-----TTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMT 493
           T +       DE     +  +R IY +HFT WPD  VP     VL        R ++ + 
Sbjct: 61  TVRLQQQRVGDEGLSAPSNEQRFIYQYHFTVWPDKGVPQYATAVL--------RFRKKII 112

Query: 494 GTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMV 553
                  A   VHCSAG+GRTG FIVID +L Q +++     +DI+  V+  R  R  MV
Sbjct: 113 NESRHNTAPWIVHCSAGVGRTGAFIVIDAMLRQAKEKKV---VDIYNYVRATRGDRPNMV 169

Query: 554 QNEAQYKFIYMAVLE 568
           Q + QY FI+ AVLE
Sbjct: 170 QTKDQYVFIHRAVLE 184



 Score =  101 bits (242), Expect = 5e-20
 Identities = 67/212 (31%), Positives = 99/212 (46%), Gaps = 15/212 (7%)

Query: 363 HVYNK--TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTE 420
           H Y +   +I TQ  L  TI  FW M+   D+  I+M     E  +    RYWP     E
Sbjct: 281 HAYRERNAFILTQAPLEDTIASFWRMVVDYDLGTIVMLNSLDEEDE-HFPRYWPSQGAEE 339

Query: 421 VVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNI 480
                  L E E     +  RRF +T K ++T +R I HF  T W DH VP +P      
Sbjct: 340 YGGIKVELQE-EDDKSFFISRRFDITTKGKSTPQR-ICHFQVTNWSDHSVPDKP------ 391

Query: 481 LLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHR 540
            LD+   L  I T         + V CS G+GR+GT   I  ++++++ E     +D+ +
Sbjct: 392 -LDLLPLLNDIQTSQQKSGDKAIVVQCSDGVGRSGTLCAIMSVIERVKVEHV---VDVFQ 447

Query: 541 TVQMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
            V+ +R  R G V+   QYKF Y   L ++++
Sbjct: 448 AVKNLRISRPGAVETLEQYKFCYDVTLAYLDS 479



 Score = 41.1 bits (92), Expect = 0.082
 Identities = 33/97 (34%), Positives = 52/97 (53%), Gaps = 8/97 (8%)

Query: 170 ATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEG-SKPEN 228
           +T IQ  +    + +L+K    P E ++   G+  EF+ L +   L    R+E  S+  N
Sbjct: 190 STDIQAPNLRNVMTKLEKIR--PREQVS---GYESEFQRLSIFW-LSPDVRVESASRACN 243

Query: 229 IRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANY 265
             KNR+ +I+P D  RV L  +  D  PG+DYINA++
Sbjct: 244 ASKNRFPDILPLDSHRVAL-HLSVDKDPGADYINASF 279


>UniRef50_A7RJD7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 352

 Score =  125 bits (301), Expect = 4e-27
 Identities = 73/212 (34%), Positives = 109/212 (51%), Gaps = 12/212 (5%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKK 424
           N  Y+A QG L  T+  FW M+   ++++++M  +E E GK+KC+RYWP+ + +T     
Sbjct: 95  NIMYLAAQGPLPKTVDDFWRMMISHNIQVVVMACREYELGKLKCKRYWPESMEETLTFAG 154

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
             I  E E +  D    R L  +  +T  K  +  FH+TAWPDH VP    R    L+++
Sbjct: 155 MKISLESEEAMGDGFTVRTLAVQAGKT--KHNVTQFHYTAWPDHDVP----RSATPLIEL 208

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
               +  +   D P    V VHCSAG GRTGT   +D     + + G   E+ +   V  
Sbjct: 209 TRSFRTFVGSQDTP----VLVHCSAGCGRTGTICALD-YARTLLQTGRTEELSVFDIVAN 263

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQR 576
           +R QR  MVQ + QY  +Y AV E +  E ++
Sbjct: 264 LRRQRVAMVQTKEQYTLVYKAVEELVNEELRK 295



 Score = 60.9 bits (141), Expect = 9e-08
 Identities = 31/73 (42%), Positives = 47/73 (64%), Gaps = 6/73 (8%)

Query: 199 KQGFWEEFETLQMMENLQLFDRM----EGSKPENIRKNRYKNIIPFDHTRVILKDIPPDG 254
           + GF +EF+ L+ + + Q  D+      G K  N  KNRYK+I+P+D++R++L +I   G
Sbjct: 20  ENGFAKEFQELKNISSRQKRDKAFSTNHGEKEYNRTKNRYKDILPYDYSRIVLPEI--KG 77

Query: 255 PPGSDYINANYIR 267
             GSDYIN NYI+
Sbjct: 78  VDGSDYINGNYIK 90


>UniRef50_Q9UMZ3 Cluster: Phosphotidylinositol phosphatase PTPRQ
            precursor; n=14; Amniota|Rep: Phosphotidylinositol
            phosphatase PTPRQ precursor - Homo sapiens (Human)
          Length = 2332

 Score =  124 bits (300), Expect = 5e-27
 Identities = 65/206 (31%), Positives = 109/206 (52%), Gaps = 15/206 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK-TEVVKKYTI 427
            +IATQG L  T+  FW M+W+   + ++M T+  E+G+++C +YWP+ NK   V     I
Sbjct: 2105 FIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVI 2164

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
                E    D+T+R   + +  +     T+   +FTAWP+H VP     +++ +      
Sbjct: 2165 TKLMEDVQIDWTIRDLKIERHGDC---MTVRQCNFTAWPEHGVPENSAPLIHFV------ 2215

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
              +++  +       + VHCSAG+GRTG FI +D +   I    F   +DI+  V  +R 
Sbjct: 2216 --KLVRASRAHDTTPMIVHCSAGVGRTGVFIALDHLTQHINDHDF---VDIYGLVAELRS 2270

Query: 548  QRSGMVQNEAQYKFIYMAVLEFIETE 573
            +R  MVQN AQY F++  +L+ +  +
Sbjct: 2271 ERMCMVQNLAQYIFLHQCILDLLSNK 2296



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 29/65 (44%), Positives = 35/65 (53%), Gaps = 4/65 (6%)

Query: 202  FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
            F EEF  L     LQ     +   P N  KNR+ NI P+++ RV  K I     PGSDYI
Sbjct: 2036 FQEEFSELPKF--LQDLSSTDADLPWNRAKNRFPNIKPYNNNRV--KLIADASVPGSDYI 2091

Query: 262  NANYI 266
            NA+YI
Sbjct: 2092 NASYI 2096


>UniRef50_UPI000065D738 Cluster: Homolog of Homo sapiens "Splice
            Isoform 3 of Tyrosine-protein phosphatase, non-receptor
            type 13; n=1; Takifugu rubripes|Rep: Homolog of Homo
            sapiens "Splice Isoform 3 of Tyrosine-protein
            phosphatase, non-receptor type 13 - Takifugu rubripes
          Length = 1845

 Score =  124 bits (299), Expect = 7e-27
 Identities = 68/204 (33%), Positives = 109/204 (53%), Gaps = 15/204 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKYTI 427
            YI+ QG L +T+  FW MIW+    ++ M T+E+ERG++KC +YWP+ L  ++    Y +
Sbjct: 1656 YISCQGPLPSTVTAFWQMIWENKSDVVAMMTQEVERGRIKCHKYWPERLGTSQDAGGYQL 1715

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
              E +     + ++   + +K ++     ++H  FT WPDH VP    +++  +     R
Sbjct: 1716 HLENQQFLEYFHIKVIRMVEK-QSGETHLVHHLKFTHWPDHGVPHSSDQLVRFI-----R 1769

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
              +++    P     V VHCSAGIGR G  I  D+IL  I     D  I++   V+ +R 
Sbjct: 1770 YMRVVHSKGP-----VTVHCSAGIGRAGVLICTDLILGLIDS---DLPINVSDIVKEMRL 1821

Query: 548  QRSGMVQNEAQYKFIYMAVLEFIE 571
            QR GM+Q + QY F Y   LE ++
Sbjct: 1822 QRHGMIQTKEQYLFCYKVWLEVLQ 1845



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 26/57 (45%), Positives = 36/57 (63%), Gaps = 8/57 (14%)

Query: 212  MENLQLFDR-MEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
            +E+L+  D  + G  PEN  KNRY++I+P+D TRV + D         DYINA+YIR
Sbjct: 1597 LEHLKPSDNCLVGKAPENRDKNRYRDILPYDKTRVAIGD-------QQDYINASYIR 1646


>UniRef50_UPI0000E45FB8 Cluster: PREDICTED: similar to PTPRT; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           PTPRT - Strongylocentrotus purpuratus
          Length = 487

 Score =  124 bits (298), Expect = 9e-27
 Identities = 72/191 (37%), Positives = 100/191 (52%), Gaps = 16/191 (8%)

Query: 369 YIATQGCLST-TIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI 427
           YI    C +  ++  FW M+W+ED   I+M T  +E  K KCE+YWPD  K  +  K T+
Sbjct: 312 YINIIACPNVASVKDFWRMVWEEDCGKIVMLTNTVEGEKRKCEKYWPD--KKMIYGKITV 369

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
             + E     YT+R F V K  E    R +  FH+T+WPD  VP     ++N +  V   
Sbjct: 370 TMKSEEVNTHYTVRTFNVVKFGENI--REVVQFHYTSWPDMGVPKYTTPLMNFIRTVKQH 427

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                  TD  +Q  + VHCSAG+GRTGTFI +D +LDQ   E     ID++  +  +R 
Sbjct: 428 ------HTD--SQGAIVVHCSAGVGRTGTFITLDAMLDQAEAEN---TIDVYNFITGMRQ 476

Query: 548 QRSGMVQNEAQ 558
            R  MVQ  +Q
Sbjct: 477 NRIKMVQVASQ 487


>UniRef50_Q6PNC4 Cluster: Protein tyrosine phosphatase non-receptor
           type 4; n=8; Euteleostomi|Rep: Protein tyrosine
           phosphatase non-receptor type 4 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 329

 Score =  124 bits (298), Expect = 9e-27
 Identities = 73/215 (33%), Positives = 113/215 (52%), Gaps = 17/215 (7%)

Query: 359 VPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK 418
           +P   + N+ YIA QG L  T   FW M W++   +++M T ++ERG+VKC +YWP+ + 
Sbjct: 115 IPACSLINR-YIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPNPSG 173

Query: 419 TEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVL 478
           +     + I  + E     + +R   +T   E+   R +    + AWPDH VP +    L
Sbjct: 174 SATYGGFQISCQTEEGNSAFLVREITLT-HIESGESRELTQIQYLAWPDHGVPDDSTDFL 232

Query: 479 NILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVID--MILDQIRKEGFDCEI 536
           + +  V  +      G D P    V VHCSAGIGRTG  I ++  M L +  +  F  EI
Sbjct: 233 DFVALVRNK----RAGKDEP----VVVHCSAGIGRTGVLITMETAMCLMECSQPVFPLEI 284

Query: 537 DIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
                V+ +RDQR+ M+Q  +Q+KF+  A+L+  E
Sbjct: 285 -----VRTMRDQRAMMIQTPSQFKFVCEAILKVYE 314



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 24/44 (54%), Positives = 29/44 (65%), Gaps = 7/44 (15%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           P+NI KNRY++I P+D TRVILK          DYINANYI  +
Sbjct: 78  PQNISKNRYRDISPYDATRVILKGT-------EDYINANYINME 114


>UniRef50_P16620 Cluster: Tyrosine-protein phosphatase 69D precursor;
            n=4; Sophophora|Rep: Tyrosine-protein phosphatase 69D
            precursor - Drosophila melanogaster (Fruit fly)
          Length = 1462

 Score =  124 bits (298), Expect = 9e-27
 Identities = 74/211 (35%), Positives = 112/211 (53%), Gaps = 24/211 (11%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY- 425
            K +I  QG + +TI  FW MIW++ + II+M T   E  K KC +YWP+  K    K++ 
Sbjct: 960  KKFICAQGPMESTIDDFWRMIWEQHLEIIVMLTNLEEYNKAKCAKYWPE--KVFDTKQFG 1017

Query: 426  TILNEF--ESSTPDYTLRRFLVTKK----DETTVKRTIYHFHFTAWPDHRVPSEPGRVLN 479
             IL +F  E  T DY  R   V+K      E   +R I  +H+  W D   P  P  ++ 
Sbjct: 1018 DILVKFAQERKTGDYIERTLNVSKNKANVGEEEDRRQITQYHYLTWKDFMAPEHPHGIIK 1077

Query: 480  ILLDVN--YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEID 537
             +  +N  Y LQ          +  + VHCSAG+GRTGT + +D ++ Q+ +E     + 
Sbjct: 1078 FIRQINSVYSLQ----------RGPILVHCSAGVGRTGTLVALDSLIQQLEEED---SVS 1124

Query: 538  IHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
            I+ TV  +R QR+ +VQ+  QY F+Y A+L+
Sbjct: 1125 IYNTVCDLRHQRNFLVQSLKQYIFLYRALLD 1155



 Score =  103 bits (247), Expect = 1e-20
 Identities = 81/283 (28%), Positives = 134/283 (47%), Gaps = 19/283 (6%)

Query: 294  PSKAKDKSSPVHTSVIVTEEPVKSSKKVHGNGTHKLPAFEPSVLRPNPN-YFNTTIPKSA 352
            P++ K K       ++ T + +  S  V  N  + +      ++  + N    T +P   
Sbjct: 1180 PNEGKCKLEVEFEKLLATADEISKSCSVGENEENNMKNRSQEIIPYDRNRVILTPLPMRE 1239

Query: 353  TETENGVPTVHVYN--KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCE 410
              T      +  Y+  +T+I  Q  L  TI  FW MI ++ V  ++M + EI  G  KC 
Sbjct: 1240 NSTYINASFIEGYDNSETFIIAQDPLENTIGDFWRMISEQSVTTLVMIS-EIGDGPRKCP 1298

Query: 411  RYWPDLNKTEVVKKYTILNEFES-STPDYTLRRFLVTK-KDETTVKRTIYHFHFTAWP-- 466
            RYW D    EV   + ++    S S P YT R F VT  K + T+K T   F +  WP  
Sbjct: 1299 RYWAD---DEVQYDHILVKYVHSESCPYYTRREFYVTNCKIDDTLKVT--QFQYNGWPTV 1353

Query: 467  DHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQ 526
            D  VP E  R +  L+D  Y         +   ++ + VHCS G  R+  F+ + +++  
Sbjct: 1354 DGEVP-EVCRGIIELVDQAYN--HYKNNKNSGCRSPLTVHCSLGTDRSSIFVAMCILVQH 1410

Query: 527  IRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEF 569
            +R E   C +DI  T + +R QR+G++ + AQY+F++ A++ +
Sbjct: 1411 LRLE--KC-VDICATTRKLRSQRTGLINSYAQYEFLHRAIINY 1450



 Score = 39.9 bits (89), Expect = 0.19
 Identities = 21/44 (47%), Positives = 26/44 (59%), Gaps = 2/44 (4%)

Query: 223  GSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            G   EN  KNR + IIP+D  RVIL  +P      S YINA++I
Sbjct: 1208 GENEENNMKNRSQEIIPYDRNRVILTPLPM--RENSTYINASFI 1249



 Score = 37.9 bits (84), Expect = 0.76
 Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 8/68 (11%)

Query: 201 GFWEEFETLQMMENLQLFDRMEGSKP--ENIRKNRYKNIIPFDHTRVILKDIPPDGPPGS 258
           GF  E+E   M+ N +  DR   +    EN  KNRY +I  +D TRV L  I  +G   +
Sbjct: 892 GFLREYE---MLPN-RFSDRTTKNSDLKENACKNRYPDIKAYDQTRVKLAVI--NGLQTT 945

Query: 259 DYINANYI 266
           DYINAN++
Sbjct: 946 DYINANFV 953


>UniRef50_UPI0000E4798C Cluster: PREDICTED: similar to phogrin; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           phogrin - Strongylocentrotus purpuratus
          Length = 533

 Score =  123 bits (297), Expect = 1e-26
 Identities = 78/224 (34%), Positives = 117/224 (52%), Gaps = 14/224 (6%)

Query: 346 TTIPKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERG 405
           T+  KS     + +  +      YIATQ  L+ T+  FW MIW++   +I+  T   E  
Sbjct: 312 TSANKSDYINSSAIMDIDPRAPAYIATQAPLANTLADFWQMIWEQGSVVIVNLTHMSETD 371

Query: 406 KVKCERYWPDLNKTEVVKKYTI-LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTA 464
             +C RYWPD   + +   Y + L        DY +R F + K  ET   RT+  FHF  
Sbjct: 372 INRC-RYWPD-EGSALYHFYEVHLVSEHVWCEDYLVRSFYL-KNLETQETRTVTQFHFLT 428

Query: 465 WPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMIL 524
           WP+   P  P      LL+   ++ +   G   P    + VHCS G+GRTGT+ ++D++L
Sbjct: 429 WPETGCPPSP----KSLLEFRRKVNKSFRGRACP----IVVHCSDGVGRTGTYCLLDLVL 480

Query: 525 DQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
            ++ K G   E+DI  T++ +RDQR GMVQ +AQ++F   AV+E
Sbjct: 481 TRMLK-GVK-ELDIAATLEHIRDQRPGMVQTQAQFEFALTAVVE 522



 Score = 45.2 bits (102), Expect = 0.005
 Identities = 23/44 (52%), Positives = 27/44 (61%), Gaps = 2/44 (4%)

Query: 223 GSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           G  PEN  KNR KN IP+DHTRV L +        SDYIN++ I
Sbjct: 284 GKAPENANKNRVKNAIPYDHTRVKLTE--ETSANKSDYINSSAI 325


>UniRef50_Q9NDP4 Cluster: Tyrosine phosphatase; n=1; Ciona
           intestinalis|Rep: Tyrosine phosphatase - Ciona
           intestinalis (Transparent sea squirt)
          Length = 987

 Score =  123 bits (297), Expect = 1e-26
 Identities = 74/211 (35%), Positives = 108/211 (51%), Gaps = 19/211 (9%)

Query: 365 YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
           +   YIA QG L  T + FW M+W++   +I+M T  +ERG+ KC +YWPD   +     
Sbjct: 752 WTNRYIACQGPLPNTSFDFWEMVWEQKSTLIVMLTTVVERGRPKCHQYWPDGGTSVQFGP 811

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDE--------TTVKRTIYHFHFTAWPDHRVPSEPGR 476
           + I +  E  TP +  R F + K +E         T  R I    + AWPDH VP +   
Sbjct: 812 FIIESVTEEVTPSFAFRDFKLYKCNEDAEVNGNDLTKGRDIRQMQYIAWPDHGVPDDSSD 871

Query: 477 VLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEI 536
            L+ +L    R++Q   G   P+     VHCSAGIGRTG  I ++  +  I        I
Sbjct: 872 FLDFVL----RVRQNRVGMAIPS----TVHCSAGIGRTGVLITMETAMCLIEANQPVYPI 923

Query: 537 DIHRTVQMVRDQRSGMVQNEAQYKFIYMAVL 567
           +I R    +RDQR+ M+Q  +Q+KF+  A+L
Sbjct: 924 EIARA---MRDQRAMMIQTPSQFKFVCDAIL 951



 Score = 47.6 bits (108), Expect = 0.001
 Identities = 22/41 (53%), Positives = 30/41 (73%), Gaps = 5/41 (12%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           P+N+ KNRY++I P+D TRVIL     +G   +DYINANY+
Sbjct: 708 PQNVTKNRYRDISPYDSTRVIL-----NGIVDTDYINANYV 743


>UniRef50_Q95Y26 Cluster: Putative uncharacterized protein Y41D4A.5;
           n=3; Caenorhabditis|Rep: Putative uncharacterized
           protein Y41D4A.5 - Caenorhabditis elegans
          Length = 456

 Score =  122 bits (295), Expect = 2e-26
 Identities = 65/188 (34%), Positives = 105/188 (55%), Gaps = 7/188 (3%)

Query: 384 WSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKYTI-LNEFESSTPDYTLR 441
           W MI +  V ++++  K +E  K+KCERYWP+ + ++E+   Y I L E +    D  L 
Sbjct: 172 WKMIDEHRVSLVVILCKLVELNKIKCERYWPEQVGESELFGDYEITLEEEKLFDDDEYLM 231

Query: 442 RFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQA 501
           R L  +   T   R ++  H+  WPDH  PS   ++LN ++D+   ++ I     P   +
Sbjct: 232 RCLKMENQTTGECRKVHQLHYREWPDHGCPSGEKQLLN-MIDL---MENIHEEVSPQDSS 287

Query: 502 VVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKF 561
            + VHCSAG+GRTGT I I+ I +Q++ E     IDI   V  +R QR+ MVQ + Q++F
Sbjct: 288 PILVHCSAGVGRTGTIIAINFIREQMKAETLH-SIDIFGLVMTLRKQRASMVQTQDQFQF 346

Query: 562 IYMAVLEF 569
           ++  +  +
Sbjct: 347 VHRCIASY 354


>UniRef50_UPI0000E49356 Cluster: PREDICTED: similar to human
           phosphotyrosine phosphatase kappa; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           human phosphotyrosine phosphatase kappa -
           Strongylocentrotus purpuratus
          Length = 721

 Score =  121 bits (291), Expect = 6e-26
 Identities = 68/203 (33%), Positives = 108/203 (53%), Gaps = 7/203 (3%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKY 425
           KT+IA Q   + +I  FW +IWQE+V  ++M T  +E GK +C  YWP ++ K++     
Sbjct: 219 KTFIAAQAPNTASINDFWRLIWQENVCSVVMVTNILEGGKDRCTVYWPKEMGKSKTFGGI 278

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            +         D+ + R L  K+      R+++ FH+ +WPD  VP  P  +++    V 
Sbjct: 279 EVKLRTIEEFSDH-VHRVLDVKQVSGGETRSVHQFHYQSWPDMGVPQYPTTLISYTQTVK 337

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
           +  ++I   T       + VHCSAG+GRTGTFI +  +L Q+ +E     +DI   +Q +
Sbjct: 338 HVHERITANT--KGSTPMLVHCSAGVGRTGTFISLYCMLAQVIEES---RVDIFGFIQKM 392

Query: 546 RDQRSGMVQNEAQYKFIYMAVLE 568
           R  R  MVQ   QY  I+ A++E
Sbjct: 393 RKDRPNMVQTADQYILIHTALVE 415



 Score = 70.5 bits (165), Expect = 1e-10
 Identities = 49/203 (24%), Positives = 92/203 (45%), Gaps = 11/203 (5%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
           ++ATQ  L  T    W M+      +I+M   E++     C +YWP+ +  +       +
Sbjct: 520 FLATQMPLPHTTGDIWRMVCDWRSPVIVMLN-ELDLQDKSCAQYWPNKDSVQFGPLKVSI 578

Query: 429 NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
              E+   DY +R+F +    + T+  T+  F    W  ++    P  +  IL  V+   
Sbjct: 579 ISAETIRSDYVMRKFEIKGPKKGTL--TVKQFQLMGWDGNQ--KRPASLAPILHLVDAVS 634

Query: 489 QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
           + + T     A   + +HC  GIGR+G F  I    +++     D  +DI ++V+ +R  
Sbjct: 635 ECVRTSQ---ASGPIVLHCINGIGRSGVFAAIYSAAEKMIT---DSSVDIFQSVKRLRAN 688

Query: 549 RSGMVQNEAQYKFIYMAVLEFIE 571
           R  M+++  QY   Y  + E+++
Sbjct: 689 RPSMIESVDQYSICYEGMAEYMK 711



 Score = 62.1 bits (144), Expect = 4e-08
 Identities = 33/71 (46%), Positives = 43/71 (60%), Gaps = 5/71 (7%)

Query: 199 KQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGS 258
           + GF  EF  L   + +    +    KPEN  KNR+KNI+ FDH+RV+L+ +  D  P S
Sbjct: 150 QDGFAHEFGLLPSDDGIA---KTVAMKPENKAKNRFKNIVAFDHSRVVLETLKDD--PHS 204

Query: 259 DYINANYIRCD 269
           DY NANYIR D
Sbjct: 205 DYYNANYIRDD 215



 Score = 37.9 bits (84), Expect = 0.76
 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 14/100 (14%)

Query: 171 TRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMME---NLQLFDRMEGSKPE 227
           T + V  F  ++  LQ+ N      +  K    +EFE L  +      Q F       P 
Sbjct: 422 TDVPVSSFEAKLSSLQERNP-----LTQKLNIEQEFEILNQLTPPVGPQAFKA--AGLPA 474

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGS-DYINANYI 266
           NI KNR+ N++P +  R  L      G  GS DYINA+++
Sbjct: 475 NIDKNRFPNVLPMEKNRPCL---VTKGEAGSTDYINASFL 511


>UniRef50_Q7Q404 Cluster: ENSANGP00000010449; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000010449 - Anopheles gambiae
           str. PEST
          Length = 994

 Score =  121 bits (291), Expect = 6e-26
 Identities = 69/201 (34%), Positives = 107/201 (53%), Gaps = 13/201 (6%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI- 427
           Y+A QG + +T+  FW M+W++   +++   +  E G+  C RYWP+    EV   Y + 
Sbjct: 762 YVAAQGPMQSTLAHFWQMVWEQGAVVLVALCRLQENGESACARYWPE-EGAEVYHIYEVH 820

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
           L        DY +R F + K   T   RT+  FHF +WP   VP+        LLD   +
Sbjct: 821 LVSEHIWCDDYLVRSFYL-KNLRTGETRTVTQFHFLSWPQGGVPTS----AKALLDFRRK 875

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
           + +   G   P    + VH S G GRTG +I++D++L ++ K     EIDI  T++ +RD
Sbjct: 876 VNKSYRGRSCP----IVVHSSNGSGRTGAYILLDLVLGRMNKGA--REIDIAATLEHLRD 929

Query: 548 QRSGMVQNEAQYKFIYMAVLE 568
           QR+G+V    Q++F+ MAV E
Sbjct: 930 QRAGLVATRQQFEFVLMAVAE 950


>UniRef50_UPI000051A879 Cluster: PREDICTED: similar to protein
           tyrosine phosphatase, receptor type, R isoform 2; n=1;
           Apis mellifera|Rep: PREDICTED: similar to protein
           tyrosine phosphatase, receptor type, R isoform 2 - Apis
           mellifera
          Length = 573

 Score =  120 bits (289), Expect = 1e-25
 Identities = 78/245 (31%), Positives = 121/245 (49%), Gaps = 23/245 (9%)

Query: 329 LPAFEPSVLRPNPNYFNTTIPKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIW 388
           LP  +  V+ P P+      P S+    N +      +  YIATQG L+ T+  FW M+W
Sbjct: 340 LPNPQSRVILPGPS----DDPLSSYINANYIRGYDGEDARYIATQGPLAHTVDDFWKMVW 395

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTILNEFESSTPDYTLRRFLVTK 447
            E V  I+M TK  E  K KCE Y+P D N       +TI+     +   YT+R   +  
Sbjct: 396 AEKVPAIVMMTKLHEAAKTKCEAYFPLDKNNRIQAGLFTIIVSSIDTREGYTIRDLELRY 455

Query: 448 KDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHC 507
           + E   ++ + H+ + +WPDH VP     ++++  +VN                 V VHC
Sbjct: 456 EGE---RKHVQHYWYDSWPDHAVPQTADTLVSLAAEVN------------SLPGPVVVHC 500

Query: 508 SAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVL 567
           SAGIGRTG FI +   + Q+ ++G    +D+   +  +R  R GMVQ   QY+F++ A+ 
Sbjct: 501 SAGIGRTGCFIALATGMTQLLRDG---NVDVLGILCQMRYDRGGMVQTAEQYEFVHRALC 557

Query: 568 EFIET 572
            + +T
Sbjct: 558 LYEQT 562



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 2/37 (5%)

Query: 231 KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           KNRY +++P   +RVIL    P   P S YINANYIR
Sbjct: 333 KNRYCSVLPNPQSRVILPG--PSDDPLSSYINANYIR 367


>UniRef50_UPI0000F2E97C Cluster: PREDICTED: similar to PTPRH
           protein; n=1; Monodelphis domestica|Rep: PREDICTED:
           similar to PTPRH protein - Monodelphis domestica
          Length = 901

 Score =  120 bits (288), Expect = 1e-25
 Identities = 71/214 (33%), Positives = 112/214 (52%), Gaps = 19/214 (8%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           + +IATQG L  T+  FW ++W++ +R +++ T       VKCE YWP   +     +  
Sbjct: 686 REFIATQGPLPQTVGDFWRLVWEQRIRSMVVLTN-----CVKCEHYWPLDAQPCNHGRLR 740

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRT--IYHFHFTAWPDHRVPSEPGRVLNILLDV 484
           +    E+    +T+R   +   D   +K+T  +  FH+T WPDH VP  P  +L     +
Sbjct: 741 VTLRGETVAEHWTVRDLHLFHMD---LKQTLCVRQFHYTVWPDHGVPHSPDPLLAFQALL 797

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
              L+Q   G  P       VHCSAG+GRTGTFI +D++L Q++K G    + +   V+ 
Sbjct: 798 RQWLEQSPEGGPP------IVHCSAGVGRTGTFIALDVLLRQLQKHG---HVGVQSFVRR 848

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVG 578
           +R  R  MVQ E QY F+Y  +L  ++  + + G
Sbjct: 849 MRRSRPLMVQTEVQYIFLYQTLLRHMQQSEDQEG 882



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 30/69 (43%), Positives = 42/69 (60%), Gaps = 8/69 (11%)

Query: 209 LQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI-- 266
           L+ +E LQ       S  EN  KNR+ N++P+D  RV L+ IP  G PGSDYINA+++  
Sbjct: 628 LESLEQLQT----AASALENKSKNRFSNVLPYDWARVPLQPIP--GDPGSDYINASFLPG 681

Query: 267 RCDSMDSIS 275
            CD  + I+
Sbjct: 682 LCDPREFIA 690


>UniRef50_Q2THU9 Cluster: PTP8; n=3; Bracovirus|Rep: PTP8 -
           Glyptapanteles indiensis bracovirus
          Length = 320

 Score =  120 bits (288), Expect = 1e-25
 Identities = 72/210 (34%), Positives = 105/210 (50%), Gaps = 8/210 (3%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYW-PDLNKTEVVK-- 423
           K Y+A QG L  TI  FW ++W+++ RII+M T+    G+ KC  YW P  NK ++ +  
Sbjct: 101 KKYVAIQGPLEETIGQFWQVVWEQNSRIIVMLTELQVAGEEKCAPYWHPYDNKQQIFQAD 160

Query: 424 KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
           + +I    ES    Y    F V     T   R I H+ +  WPD  VPS+      ++  
Sbjct: 161 ELSIRTVSESKESGYVETTFDVFNCC-TEESRLIKHYMYLDWPDRGVPSDWDSFKQLICT 219

Query: 484 VNYRLQQIMTG-TDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
           V+   Q+++    D PA   + VHCSAG+GRTG F  +D    Q+ K      + +  TV
Sbjct: 220 VDKERQRLLAEMADGPALGPIIVHCSAGVGRTGVFCAVDSCFYQLVKTE---TVSVPETV 276

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
             +R QR   V    QY FIY  + EF ++
Sbjct: 277 LRIRQQRYSSVSTTEQYVFIYKILYEFAQS 306



 Score = 44.8 bits (101), Expect = 0.007
 Identities = 24/45 (53%), Positives = 30/45 (66%), Gaps = 4/45 (8%)

Query: 224 SKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRC 268
           SK EN++KNRY +II  D TRV  K  P  G   +DYI+ANY+ C
Sbjct: 56  SKQENLKKNRYDDIICLDATRV--KITPKKG--NTDYIHANYVDC 96


>UniRef50_UPI0000F2AE09 Cluster: PREDICTED: hypothetical protein;
           n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
           protein - Monodelphis domestica
          Length = 454

 Score =  119 bits (287), Expect = 2e-25
 Identities = 67/203 (33%), Positives = 102/203 (50%), Gaps = 15/203 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
           YIATQ  L  T   FW M+W+    +I M TKE+E G +KC  YWP  L K   ++ + +
Sbjct: 254 YIATQAPLPGTTEDFWQMVWENKSNVIAMITKEMEDGIIKCHPYWPISLTKPLGLQNFLV 313

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
             E       + +R F +  K   +V   ++   F  WPDH +P+     ++ +     R
Sbjct: 314 ELENTQILEAFIIRVFKIVNKSTGSV-HFVHQIQFMNWPDHGIPTSYEAFVSYI-----R 367

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
             + +  T P     +  HCSAGIGRTG  + +D++L  +     D E DI   V  +R+
Sbjct: 368 YMKKIHETGP-----IIAHCSAGIGRTGVLLCMDVVLHALEN---DLEFDIKTIVTQMRN 419

Query: 548 QRSGMVQNEAQYKFIYMAVLEFI 570
           QR GM+Q + QY+F Y  V+  +
Sbjct: 420 QRCGMIQTKEQYQFCYETVIHVL 442



 Score = 56.0 bits (129), Expect = 3e-06
 Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 10/116 (8%)

Query: 153 PMVETTGE-VLRLIQPFNATRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQM 211
           P+V +TGE ++   +    + I+     T ++   +     IE    ++  +EEF  L+ 
Sbjct: 138 PIVTSTGEKIITEEELIEISEIRPNLSGTLLRSTVRNLIEDIEKRIDQKEIFEEFLALEN 197

Query: 212 MENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
            E L   D + G+ PEN  KNRY++IIP+D TRV +           DYINANYIR
Sbjct: 198 RELLD--DCILGNNPENRDKNRYRDIIPYDRTRVSIGQ-------SQDYINANYIR 244


>UniRef50_Q9W0G1 Cluster: Tyrosine-protein phosphatase non-receptor
           type 61F; n=6; Diptera|Rep: Tyrosine-protein phosphatase
           non-receptor type 61F - Drosophila melanogaster (Fruit
           fly)
          Length = 548

 Score =  119 bits (287), Expect = 2e-25
 Identities = 72/210 (34%), Positives = 108/210 (51%), Gaps = 15/210 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVK-- 423
           + YI TQG L  T+  FW M+W++  R ++M  K +E+ ++KC  YWP ++   + +K  
Sbjct: 99  RQYILTQGPLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLP 158

Query: 424 --KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
             K T+       T    +RR+      ET   R +  FH+T WPD  +PS P   L  L
Sbjct: 159 HVKLTV-ELVRLETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFL 217

Query: 482 LDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
             V  R    ++    PA     VHCSAGIGR+GTF ++D  L  I K G   E ++ + 
Sbjct: 218 QQV--RDSGCLSRDVGPA----VVHCSAGIGRSGTFCLVDCCLVLIDKYG---ECNVSKV 268

Query: 542 VQMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
           +  +R  R G++Q   Q  F Y A++E I+
Sbjct: 269 LCELRSYRMGLIQTADQLDFSYQAIIEGIK 298



 Score = 40.3 bits (90), Expect = 0.14
 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 8/87 (9%)

Query: 184 QLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHT 243
           +LQ E E   +   + + + E  ET       + F   E  +  N   NRY+++ P+DH+
Sbjct: 16  RLQIEAEYKDKGPQWHRFYKEICETCDREAKEKQFSTSESERHTNRGLNRYRDVNPYDHS 75

Query: 244 RVILKDIPPDGPPGS-DYINANYIRCD 269
           R++LK        GS DYINAN ++ +
Sbjct: 76  RIVLK-------RGSVDYINANLVQLE 95


>UniRef50_P28191 Cluster: Tyrosine-protein phosphatase 1; n=4;
            Caenorhabditis|Rep: Tyrosine-protein phosphatase 1 -
            Caenorhabditis elegans
          Length = 1026

 Score =  119 bits (287), Expect = 2e-25
 Identities = 68/209 (32%), Positives = 110/209 (52%), Gaps = 13/209 (6%)

Query: 359  VPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK 418
            +P+  + N+ YIA QG L+ T   FW M+W++    I+M T   ERG+VKC +YWP + +
Sbjct: 814  IPSSGIVNR-YIACQGPLAHTSSDFWVMVWEQHCTTIVMLTTITERGRVKCHQYWPRVFE 872

Query: 419  TEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVL 478
            T+   +  I    +  T +   R F +  ++ ++ +R +    + AWPDH VP +P   +
Sbjct: 873  TQEYGRLMIKCIKDKQTTNCCYREFSIRDRN-SSEERRVTQMQYIAWPDHGVPDDPKHFI 931

Query: 479  NILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
              + +V    Q      DP     + VHCSAGIGRTG  I+++     +        +DI
Sbjct: 932  QFVDEVRKARQ---GSVDP-----IVVHCSAGIGRTGVLILMETAACLVESNEPVYPLDI 983

Query: 539  HRTVQMVRDQRSGMVQNEAQYKFIYMAVL 567
             RT   +RDQR+ ++Q   QY F+  ++L
Sbjct: 984  VRT---MRDQRAMLIQTPGQYTFVCESIL 1009



 Score = 44.0 bits (99), Expect = 0.012
 Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 5/42 (11%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           N+ KNRY+++ P+D TRV L+       P  DYINANY+  +
Sbjct: 777 NLAKNRYRDVCPYDDTRVTLQ-----ASPSGDYINANYVNME 813


>UniRef50_UPI00015B643E Cluster: PREDICTED: similar to
           ENSANGP00000011584; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000011584 - Nasonia
           vitripennis
          Length = 715

 Score =  118 bits (285), Expect = 3e-25
 Identities = 66/206 (32%), Positives = 108/206 (52%), Gaps = 12/206 (5%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP---DLNKTEVVKKY 425
           YI TQG +  T+  FW M+WQE    I+M TK  +  KV C +YWP   D ++       
Sbjct: 202 YIVTQGPMENTVVEFWRMVWQERAACIVMLTKTFDFIKVMCMQYWPASKDKDEDYGGIGV 261

Query: 426 TILNEFE-SSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
           ++L E E ++    T++ +   +KDE T +RTI  FH+T W  H  P       N +L+ 
Sbjct: 262 SVLAEEELANFHIRTIKLYKKDEKDEVTEERTILQFHYTEWHSHTCPFG-----NAVLEF 316

Query: 485 NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
             R++ ++  T       + VHC+ G GR+G ++ ID  ++   +E      D+   ++ 
Sbjct: 317 RRRVRAVVGSTLKSEAGPMVVHCNDGGGRSGVYLAIDANMELAEEED---AFDVFGYLKK 373

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLEFI 570
           +R  R G+++N  QYKF+Y  + EF+
Sbjct: 374 LRQSRKGLIENLEQYKFVYDTLEEFV 399



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 47/215 (21%), Positives = 95/215 (44%), Gaps = 22/215 (10%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKY 425
           + YI T+  ++ ++  FWS+++  +   +++       G      +WP+  +  +    +
Sbjct: 500 REYIVTEWPVTRSLGEFWSLVYDYECAAVVVLCVP-PAGSTNYPSFWPEGRHSKKYGPVF 558

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVK---------RTIYHFHFTAWP-DHRVPSEPG 475
           TI +   +   +     F + KK  +  +         +T+  F  T WP    VP+   
Sbjct: 559 TIDHISHNHYTNIKTWVFRINKKIVSLTELMAGVKAPPKTVQLFQLTCWPMGQAVPTST- 617

Query: 476 RVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCE 535
              N L+++   +++    TD    AVV      G  R G +   +  ++Q+ + G   E
Sbjct: 618 ---NSLVELMNMVERWRQRTDYGPVAVVSPD---GRSRCGVYCAANACIEQVIQHG---E 668

Query: 536 IDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
           +DI + V+ VR  R  +V+N  +YK+ Y  VL ++
Sbjct: 669 VDIFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYV 703



 Score = 46.4 bits (105), Expect = 0.002
 Identities = 25/62 (40%), Positives = 36/62 (58%), Gaps = 5/62 (8%)

Query: 205 EFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINAN 264
           EF+T   +E          +KP N  KN+ +  IP+D+ RV+L+ I  DG   SDYINA+
Sbjct: 137 EFQTATKVETHSC---RHATKPANREKNQNQKCIPYDYNRVVLETI--DGRADSDYINAS 191

Query: 265 YI 266
           Y+
Sbjct: 192 YV 193


>UniRef50_UPI0000D55E2F Cluster: PREDICTED: similar to CG18243-PA;
            n=1; Tribolium castaneum|Rep: PREDICTED: similar to
            CG18243-PA - Tribolium castaneum
          Length = 1083

 Score =  118 bits (285), Expect = 3e-25
 Identities = 71/205 (34%), Positives = 108/205 (52%), Gaps = 15/205 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV-KKYTI 427
            YIATQG L +T   FW M+ QE+V II+M ++ +E+ K KC  Y+P  +++ +  +   +
Sbjct: 856  YIATQGPLESTTRDFWKMVLQENVSIIVMVSQFVEQSKEKCYHYFPSNHESVMFGESLEV 915

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
                E     Y +R   V K  E   +R + H  F  WPD  VP     +L     +  +
Sbjct: 916  KCCTELHFGTYCMRTLQVRKGTE---QRHVIHMQFLEWPDFGVPLGTDNMLQFCRQLREK 972

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                          ++ VHCSAG+GRTGT I +D++L  I       +I+I++TV  +R 
Sbjct: 973  ANS--------EGGLIVVHCSAGVGRTGTLIALDILLQTIDDHR---DINIYKTVLDLRK 1021

Query: 548  QRSGMVQNEAQYKFIYMAVLEFIET 572
            QR+ MVQ E QY FI+  V +++ET
Sbjct: 1022 QRANMVQTEKQYVFIHTCVNDYLET 1046



 Score = 52.0 bits (119), Expect = 4e-05
 Identities = 26/41 (63%), Positives = 30/41 (73%), Gaps = 1/41 (2%)

Query: 227 ENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           EN RKNRY NI+PFD TRV L +I  D    SDYINA+YI+
Sbjct: 809 ENRRKNRYTNILPFDETRVKL-NIDEDDEISSDYINASYIK 848


>UniRef50_Q5BVG2 Cluster: SJCHGC04925 protein; n=2; Schistosoma
           japonicum|Rep: SJCHGC04925 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 359

 Score =  118 bits (285), Expect = 3e-25
 Identities = 86/297 (28%), Positives = 142/297 (47%), Gaps = 22/297 (7%)

Query: 277 SQEFTGNGSTENGKDGTPSKAKDKSSPVHTSVIVTEEPVKSSKKVHGNGTHKLPAFEPSV 336
           S+EF  + S  +  D    +A+ +S   +     +    +S + +  N    + A++ S 
Sbjct: 46  SKEFHAHVSAYHADDDAGFQAEFESLEQNVQTDWSTSVARSLENIAKNRYSNVLAYDHSR 105

Query: 337 LRPNPNYFNTTIPKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIII 396
           +         T  KS     N V   H     YIA QG + +T   FW M+W+++  II+
Sbjct: 106 V-----ILKETTNKSDYINANYVDGYH-RRAAYIAAQGPIPSTFDDFWLMVWEQNSNIIV 159

Query: 397 MTTKEIERGKVKCERYWPDL-NKTEVVKKYTILNEFESSTPDYTLRRFLV--TKKDETTV 453
           M +  +ERG+ KC++YWP   ++T       +++E   +   YT+R F V   K      
Sbjct: 160 MISNFVERGRRKCDKYWPSSGHRTYGNISVRLISEVIRAF--YTIRVFTVRHIKTKRGNK 217

Query: 454 KRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGR 513
            R +YH+ +T W D  VP  P   L +L  V   +        P     + VHCSAG+GR
Sbjct: 218 DRLVYHYQYTDWRDFDVPPSP---LPVLKFVEASVTHWTFDKGP-----IVVHCSAGVGR 269

Query: 514 TGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
           TGT+I I+ ++ Q++ E     + +   ++ +R QR  +VQ E QY FI+  + E+I
Sbjct: 270 TGTYICIESLIRQLKVEH---AVSVCGFLEHIRQQRMKLVQTEQQYAFIHDVLREYI 323



 Score = 55.6 bits (128), Expect = 4e-06
 Identities = 31/67 (46%), Positives = 42/67 (62%), Gaps = 7/67 (10%)

Query: 201 GFWEEFETLQMMENLQL-FDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSD 259
           GF  EFE+L+  +N+Q  +        ENI KNRY N++ +DH+RVILK+        SD
Sbjct: 63  GFQAEFESLE--QNVQTDWSTSVARSLENIAKNRYSNVLAYDHSRVILKETTNK----SD 116

Query: 260 YINANYI 266
           YINANY+
Sbjct: 117 YINANYV 123


>UniRef50_UPI0000D56953 Cluster: PREDICTED: similar to Receptor-type
           tyrosine-protein phosphatase alpha precursor
           (Protein-tyrosine phosphatase alpha) (R-PTP-alpha); n=1;
           Tribolium castaneum|Rep: PREDICTED: similar to
           Receptor-type tyrosine-protein phosphatase alpha
           precursor (Protein-tyrosine phosphatase alpha)
           (R-PTP-alpha) - Tribolium castaneum
          Length = 590

 Score =  118 bits (283), Expect = 6e-25
 Identities = 68/203 (33%), Positives = 108/203 (53%), Gaps = 16/203 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           + +IATQ   S T+  FW MI +++V IIIM T+  E G++KC +YWPD        K +
Sbjct: 97  QAFIATQAPSSGTVEDFWLMICEQNVSIIIMLTELRENGRIKCVQYWPDFQSRCRFGKIS 156

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
           + N    + P Y+ R   +  ++ T     + HF +  WPDH VP       N       
Sbjct: 157 LENISTKNFPHYSRREIKIHYRNRTYF---VQHFQYVTWPDHGVPLCRQGFTNF------ 207

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
            L++IM   + P  + + VHC+AG GRTGTFI+  + +   +KE    E++ ++ ++ +R
Sbjct: 208 -LKEIM---EIPQTSPIVVHCNAGCGRTGTFILCAIAISVAKKEN---EVNFYKLLKHMR 260

Query: 547 DQRSGMVQNEAQYKFIYMAVLEF 569
           +QR  +V    QY F +  VLE+
Sbjct: 261 EQRPRVVTTADQYIFAHFVVLEY 283



 Score = 97.5 bits (232), Expect = 9e-19
 Identities = 67/209 (32%), Positives = 100/209 (47%), Gaps = 15/209 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKY 425
           K YIATQG    TI  FW MIWQE    I+M T  +E  K KC  Y+P  L       + 
Sbjct: 346 KVYIATQGPKFATIRDFWRMIWQEQADTIVMATNFMEDKKRKCGEYFPQRLGTLCEYGEM 405

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
            I    E     Y  R F+V+ ++    +R I HF     PD   P       N L+ + 
Sbjct: 406 RIKLVSERLFEHYDSRIFVVSYRES---ERRIQHFQMKWSPDDLKP----LYANCLVPLV 458

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
            R+++I   +  P    + +HCS+G+ RTGT I+ D+ L           +D +  ++ +
Sbjct: 459 KRIREIRMNSKKP----MVIHCSSGMNRTGTLILCDLALQMAETVK---AVDFYALLKKM 511

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
           R++R  M+ +E QY   ++ VLE +  EK
Sbjct: 512 RNERPNMITSEKQYVLAHLVVLECLTEEK 540



 Score = 53.2 bits (122), Expect = 2e-05
 Identities = 25/42 (59%), Positives = 31/42 (73%), Gaps = 4/42 (9%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           K EN RKNRYK I+P+D TRVIL+    +   G+DYINAN+I
Sbjct: 53  KVENARKNRYKTILPYDETRVILR----ESEDGNDYINANFI 90


>UniRef50_UPI00005A3E04 Cluster: PREDICTED: similar to protein
            tyrosine phosphatase, receptor type, sigma isoform 2
            precursor; n=1; Canis lupus familiaris|Rep: PREDICTED:
            similar to protein tyrosine phosphatase, receptor type,
            sigma isoform 2 precursor - Canis familiaris
          Length = 1738

 Score =  118 bits (283), Expect = 6e-25
 Identities = 103/357 (28%), Positives = 165/357 (46%), Gaps = 32/357 (8%)

Query: 228  NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCDSMDSISDSQEF--TGNGS 285
            N  KNRY N+I +DH+RVIL+  P +G  GSD     YI  + +D       +  T    
Sbjct: 1392 NKPKNRYANVIAYDHSRVILQ--PIEGIVGSD-----YINANYVDGYRRQNAYIATQGPL 1444

Query: 286  TENGKDGTPSKAKDKSSPVHTSVIVTEEP-----VKSSKKVHGNGTHKLPAFEPSVLRPN 340
             E   D      + +S+ +     + E+      ++   K   N       F  + L  N
Sbjct: 1445 PETFGDFWRMVWEQRSATIVMMTRLEEKSRHVTGMELEFKRLANSKAHTSRFISANLPCN 1504

Query: 341  P--NYFNTTIPKSAT----ETENGVPTVHVYNKTYIATQGCLSTTI-YPFWSMIWQEDVR 393
               N     +P  +T    +   GV      N ++I    CL+  +     S+ W+ ++ 
Sbjct: 1505 KFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRCLAFALPRGVSSLPWETELG 1564

Query: 394  IIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTV 453
             +  + K   +G    ++  P   +  V + +T+    E + P Y LR F VT   +   
Sbjct: 1565 ALPASCKAPAQGGRWAQKA-PPARRLGVTEGFTVDPMAEYNMPQYILREFKVTDARDGQ- 1622

Query: 454  KRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGR 513
             RT+  F FT WP+  VP      ++ +  V+   +Q   G D P    + VHCSAG+GR
Sbjct: 1623 SRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQF--GQDGP----ISVHCSAGVGR 1676

Query: 514  TGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
            TG FI + ++L+++R EG    +DI +TV+M+R QR  MVQ E +Y+F Y A LE++
Sbjct: 1677 TGVFITLSIVLERMRYEGV---VDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYL 1730



 Score = 41.5 bits (93), Expect = 0.062
 Identities = 22/41 (53%), Positives = 28/41 (68%), Gaps = 2/41 (4%)

Query: 226  PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
            P N  KNR  NI+P++ TRV L+  P  G  GSDYINA++I
Sbjct: 1502 PCNKFKNRLVNIMPYESTRVCLQ--PIRGVEGSDYINASFI 1540


>UniRef50_UPI0000F2E7E7 Cluster: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 2 (T-cell
           protein-tyrosine phosphatase) (TCPTP); n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to Tyrosine-protein
           phosphatase non-receptor type 2 (T-cell protein-tyrosine
           phosphatase) (TCPTP) - Monodelphis domestica
          Length = 612

 Score =  117 bits (282), Expect = 8e-25
 Identities = 68/208 (32%), Positives = 104/208 (50%), Gaps = 8/208 (3%)

Query: 362 VHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYW-PDLNKTE 420
           + V  + YI TQG L  T   FW M+WQ++ R ++M  K +ER  +KC +YW P L ++ 
Sbjct: 397 MQVAQRKYILTQGPLPNTCGHFWLMVWQQNSRGVVMLNKLVERSSIKCSQYWPPHLGQSL 456

Query: 421 VVKKYTILNEFE-SSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLN 479
           + ++ +I    E      Y     L  +   T  K+ I HF FT WPD  VP  P   L 
Sbjct: 457 LFEEMSISVHLEGEDVRAYYKIHHLRLENMVTGEKKPISHFQFTQWPDLGVPESPIPFLA 516

Query: 480 ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
            L  V        +G     Q  V +HC++GIGR+G F ++D  L  +  +     ++I 
Sbjct: 517 FLSVVR------DSGCLSHEQGPVVIHCTSGIGRSGVFALVDACLVMMESKEHPFSLNIR 570

Query: 540 RTVQMVRDQRSGMVQNEAQYKFIYMAVL 567
           + +  +R  R G++Q   Q +F YMAV+
Sbjct: 571 QVLVNMRKYRMGLIQTPEQLRFSYMAVI 598



 Score = 35.1 bits (77), Expect = 5.4
 Identities = 17/41 (41%), Positives = 27/41 (65%), Gaps = 2/41 (4%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           PEN  +NR++ + P+DH+RV LK    +    +DYINA+ +
Sbjct: 357 PENRYRNRHRYVSPYDHSRVRLKAAFRNA--HNDYINASLV 395


>UniRef50_Q3TU63 Cluster: 15 days embryo head cDNA, RIKEN
           full-length enriched library, clone:4022406H20
           product:protein tyrosine phosphatase, receptor type, E,
           full insert sequence; n=4; Euteleostomi|Rep: 15 days
           embryo head cDNA, RIKEN full-length enriched library,
           clone:4022406H20 product:protein tyrosine phosphatase,
           receptor type, E, full insert sequence - Mus musculus
           (Mouse)
          Length = 483

 Score =  117 bits (282), Expect = 8e-25
 Identities = 68/190 (35%), Positives = 98/190 (51%), Gaps = 14/190 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
           +IA QG    T+  FW M+W++    I+M T   ER + KC +YWPD           + 
Sbjct: 146 FIAAQGPKQETVNDFWRMVWEQRSATIVMLTNLKERKEEKCYQYWPD-QGCWTYGNIRVC 204

Query: 429 NEFESSTPDYTLRRFLVTKK--DETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            E      DYT+R+F +  +  D     R +   HFT+WPD  VP  P  +L        
Sbjct: 205 VEDCVVLVDYTIRKFCIHPQLPDSCKAPRLVSQLHFTSWPDFGVPFTPIGMLKF------ 258

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
            L+++ T  +P     + VHCSAG+GRTGTFIVID ++D I  E    ++D+   V  +R
Sbjct: 259 -LKKVKT-LNPSHAGPIVVHCSAGVGRTGTFIVIDAMMDMIHSEQ---KVDVFEFVSRIR 313

Query: 547 DQRSGMVQNE 556
           +QR  MVQ +
Sbjct: 314 NQRPQMVQTD 323



 Score = 57.2 bits (132), Expect = 1e-06
 Identities = 36/79 (45%), Positives = 44/79 (55%), Gaps = 4/79 (5%)

Query: 188 ENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVIL 247
           E E  + S    + F EEF +L        F+    +K EN  KNRY NI+P DH RVIL
Sbjct: 63  EEEIRVRSADDCKRFREEFNSLPSGHIQGTFEL--ANKEENREKNRYPNILPNDHCRVIL 120

Query: 248 KDIPPDGPPGSDYINANYI 266
             +  DG P SDYINA+YI
Sbjct: 121 SQV--DGIPCSDYINASYI 137


>UniRef50_Q69HS3 Cluster: Receptor tyrosine phosphatase-like; n=1;
           Ciona intestinalis|Rep: Receptor tyrosine
           phosphatase-like - Ciona intestinalis (Transparent sea
           squirt)
          Length = 445

 Score =  117 bits (281), Expect = 1e-24
 Identities = 68/195 (34%), Positives = 99/195 (50%), Gaps = 12/195 (6%)

Query: 386 MIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLV 445
           M+W+ +  +I+M  K +E GK KCE+YWPD N T+      +    E     +T R F +
Sbjct: 1   MVWETESSVIVMLAKLVENGKKKCEKYWPDYNGTKSYPSMQVTCTQEEVFGCFTARSFTM 60

Query: 446 TKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCV 505
           T+   T   R I  FH+T WPDH VP     +      V  + Q+   G + P    + V
Sbjct: 61  TRWGAT---RQITQFHYTTWPDHGVPITTSGLHAFKRAVLGKQQEF--GRNKP----IVV 111

Query: 506 HCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMA 565
           HCSAG GRTGTFI  D +  ++ ++     +++++TV  +R QR  MVQ E QY  ++  
Sbjct: 112 HCSAGAGRTGTFIAFDSLTMEMNQKD---NVNVYQTVLGMRRQRVEMVQTEKQYMLLHKL 168

Query: 566 VLEFIETEKQRVGLG 580
           V E        VG G
Sbjct: 169 VAEEYALGTTEVGFG 183



 Score = 74.1 bits (174), Expect = 9e-12
 Identities = 64/235 (27%), Positives = 106/235 (45%), Gaps = 22/235 (9%)

Query: 343 YFNTTIPKSATETENGVPTVHVYNKT---YIATQGCLSTTIYPFWSMIWQEDVRIIIMTT 399
           +F     + A  ++     +  Y++T    IA +G    TI  FW  +    V  I+   
Sbjct: 218 HFRIMDDRFAPASKYNASFIESYDRTKTEMIAAEGPTEATIKGFWGAVLSNQVHTIVSLR 277

Query: 400 KEIERGKVKC--ERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTI 457
              E  K +C      P  N    V K  +L E ++   D T R   ++      ++  I
Sbjct: 278 SSSEETKHRCMPSLQMPTRNFDNFVVK--LLTESDAGN-DVTQRELHLSHGAGEQIE--I 332

Query: 458 YHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTF 517
             +HF  W  + +PS  G VL  L+    + +   +G        V V+CS G+GRTG F
Sbjct: 333 GFYHFDNWLPNSIPS-CGDVLE-LIKKTQKSKLHRSGK-------VLVYCSDGVGRTGVF 383

Query: 518 IVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
             +  ++++ + EG   +ID+   V+ +R+ R GMV  E  Y+FIY  ++EF+ T
Sbjct: 384 FGVLNLIERAKLEG---KIDVPWQVKDMREMRQGMVNAEVLYRFIYQCLVEFVST 435


>UniRef50_Q17JS6 Cluster: Protein tyrosine phosphatase, non-receptor
           type nt1; n=2; Aedes aegypti|Rep: Protein tyrosine
           phosphatase, non-receptor type nt1 - Aedes aegypti
           (Yellowfever mosquito)
          Length = 503

 Score =  117 bits (281), Expect = 1e-24
 Identities = 69/207 (33%), Positives = 107/207 (51%), Gaps = 13/207 (6%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL----NKTEVV 422
           + YI  QG L  T+  FW M+W+ + R I+M  K IE+ ++KC  YWP+     +K E+ 
Sbjct: 6   RKYILCQGPLPLTVGHFWLMVWEYNSRAILMLNKLIEKKQIKCHLYWPEKIGEEHKLELP 65

Query: 423 KKYTILNEFES-STPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
           +    +   +     ++  R F +T   E++  R +  FH+T WPD  +PS P   L  L
Sbjct: 66  EVQLAIEYVKCVEYKNFCKRTFRLTDM-ESSKTREVVQFHYTTWPDFGIPSSPVAFLQFL 124

Query: 482 LDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
            +V      +     PP      +HCSAGIGR+GTF ++D  L  I KEG D ++ +   
Sbjct: 125 KEVR-ESGALDKDVGPP-----IIHCSAGIGRSGTFCLVDCCLVLIDKEGED-KVAVQDV 177

Query: 542 VQMVRDQRSGMVQNEAQYKFIYMAVLE 568
           +  +R  R G++Q   Q  F Y A++E
Sbjct: 178 LLELRRYRMGLIQTVDQLYFSYQAIIE 204


>UniRef50_A3LZ13 Cluster: Predicted protein; n=3;
           Saccharomycetales|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 324

 Score =  117 bits (281), Expect = 1e-24
 Identities = 80/232 (34%), Positives = 121/232 (52%), Gaps = 37/232 (15%)

Query: 362 VHVYNKTYIATQGCLSTTIYPFWSMIWQE------DVRIIIMTTKEIERGKVKCERYWPD 415
           V +Y  TYIA QG L  T+  FWSM + E      +V +I+M T   E G VKC RYWPD
Sbjct: 88  VKLYKSTYIAAQGPLEATVNQFWSMAYNESEKQNNEVILIVMVTPLTESGMVKCNRYWPD 147

Query: 416 L----------NKTEVVKKYTILNEFESSTPDYTLRRFLVTKKD--ETTVKRTIYHFHFT 463
                      NK + +    +  E  S T D  +  FL+T+ +   ++  + +YHF++ 
Sbjct: 148 KDQKVLEMAAENKQDGIDISGLTLEHVSETYD-EIGDFLLTEMNLKSSSKSKKVYHFYYY 206

Query: 464 AWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMI 523
            W D RVP+    +L +  ++N  +++++   +PP   +  VHCSAG+GRTGTFI ID +
Sbjct: 207 KWADSRVPASIYPLLYLSEEIN-SIRKLVE--NPP---IPIVHCSAGVGRTGTFIAIDHL 260

Query: 524 LDQIRK-----------EGFDCEID-IHRTVQMVRDQRSGMVQNEAQYKFIY 563
                K           +G+D + D + +TV  +RD R  MVQ   Q+ F+Y
Sbjct: 261 FRDFDKFIAVCDKAKSSKGYDIDFDPVFQTVLQLRDSRMMMVQTAYQFSFLY 312



 Score = 40.7 bits (91), Expect = 0.11
 Identities = 19/46 (41%), Positives = 30/46 (65%), Gaps = 2/46 (4%)

Query: 222 EGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           +G    N ++NRY N+ P+D +RV L  +  D   G+DYINA+Y++
Sbjct: 46  DGINKANAKRNRYTNVFPYDISRVKL-PLNEDA-TGTDYINASYVK 89


>UniRef50_Q9Y1X4 Cluster: SPTPR5; n=1; Ephydatia fluviatilis|Rep:
           SPTPR5 - Ephydatia fluviatilis
          Length = 446

 Score =  116 bits (278), Expect = 2e-24
 Identities = 67/182 (36%), Positives = 97/182 (53%), Gaps = 14/182 (7%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKK 448
           + +V  I+M T  +E GK KC +YWP  + T       +  E     PD+T+R   VT  
Sbjct: 1   EHNVPTIVMLTNIMEEGKAKCSQYWPSGSGTLQYGGLLVKVETTIILPDHTIRSLTVTSP 60

Query: 449 DETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCS 508
              T  RT+ HFH+T W D+  P+    ++N +  VN     ++ G        + VHCS
Sbjct: 61  SGDT--RTVLHFHYTNWHDYGTPTHLAPLINFVRVVNQ--SHVVHGP-------LLVHCS 109

Query: 509 AGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
           AG+GRTGT I ID  + QI  EG   E+D+   V ++R+QR+ MVQ E Q+  I+  +LE
Sbjct: 110 AGVGRTGTVIAIDYCMKQIHMEG---EVDVKGVVSVLREQRNFMVQTEQQFTCIHYVLLE 166

Query: 569 FI 570
            I
Sbjct: 167 AI 168



 Score = 64.1 bits (149), Expect = 1e-08
 Identities = 49/208 (23%), Positives = 90/208 (43%), Gaps = 15/208 (7%)

Query: 363 HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
           ++  + +I   G    TI  FW M+       II  T       V  + YWP  N+   +
Sbjct: 246 YLNTQQFIVADGPCVDTIEHFWQMLVNNGCSNIITLTPS----DVGVDPYWPPCNQMMSL 301

Query: 423 KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
              ++    E     Y +R+ ++T +  +T    +  + +  W   ++    G V   + 
Sbjct: 302 TNISVEVVEEQPEHMYNVRKIMLTNRTGST--HLVMQYEYIGWTAEKMTDVSGFV-QFVF 358

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
           DV  R+ +            + VH +  +G +G F  +   ++++R E     +D+ + V
Sbjct: 359 DVARRIDE-----GNYTNNAILVHDTTSLGPSGIFCALWHCMERLRLERV---VDVFQAV 410

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
           Q ++ Q+ GMV++  QY FIY  V EFI
Sbjct: 411 QKLQLQKPGMVESVKQYAFIYDCVHEFI 438


>UniRef50_P28192 Cluster: Tyrosine-protein phosphatase 2 precursor;
           n=2; Caenorhabditis|Rep: Tyrosine-protein phosphatase 2
           precursor - Caenorhabditis elegans
          Length = 1159

 Score =  115 bits (277), Expect = 3e-24
 Identities = 73/211 (34%), Positives = 107/211 (50%), Gaps = 15/211 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
           YIATQ  L +T   FWSMIWQE   II+  T  +E GK KC++YWP   +  +    Y +
Sbjct: 714 YIATQAPLPSTFSDFWSMIWQERSNIIVCITNMVEDGKRKCDQYWPSQQDSPQTFGNYQV 773

Query: 428 LNEFESSTPDYTLRRF-LVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
               ES+   ++ R   L   K    V+R ++  HF  WPDH VPS    V  +L  V+Y
Sbjct: 774 TLVSESTNAHFSHRILDLKIAKAVPAVERKVHQLHFMGWPDHGVPSS---VFPLLSFVHY 830

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
                 TG        V VHCSAG+GR+G++I++D +   +        +++   +  +R
Sbjct: 831 TSDIHSTGP-------VVVHCSAGVGRSGSYILVDSMRRHLISFR---RLNVQGHLTHMR 880

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
            QR+ +VQ   QY F + A+ + I     RV
Sbjct: 881 RQRAKLVQTLEQYIFCHEAIRQLIRHGITRV 911



 Score = 41.5 bits (93), Expect = 0.062
 Identities = 21/43 (48%), Positives = 27/43 (62%), Gaps = 5/43 (11%)

Query: 224 SKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           S  EN +KNRY NI   + TR+ L     + P G+DYINANY+
Sbjct: 668 SSDENSQKNRYNNIGAIEATRIRL-----NSPTGNDYINANYV 705


>UniRef50_Q9Y1X2 Cluster: SPTPN1; n=1; Ephydatia fluviatilis|Rep:
           SPTPN1 - Ephydatia fluviatilis
          Length = 180

 Score =  115 bits (276), Expect = 4e-24
 Identities = 69/186 (37%), Positives = 102/186 (54%), Gaps = 15/186 (8%)

Query: 392 VRIIIMTTKEIERGKVKCERYWPDLNKTE---VVKKYTILNEFESSTPDYTLRRFLVTKK 448
           V +I+MTTK +E  KVKC  YW D  + +   V+ + T + +FE     Y  R   V  +
Sbjct: 4   VLVIVMTTKLVEAAKVKCAEYWSDERQEQHGGVIIQVTKVEKFEG----YEQRTMRVQFE 59

Query: 449 DETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY-RLQQIMTGTDPPAQAV-VCVH 506
            E   +RT+ HF F AWPD+ +PS    VLN+L  V   + +Q  T    P     V VH
Sbjct: 60  GE---ERTLAHFQFLAWPDYGIPSSGSSVLNLLRAVRETQAKQAKTVAGMPLYGPPVLVH 116

Query: 507 CSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAV 566
           CSAG+GR+G F  ID  +D++R  G   ++++   V+ +R QR+  +Q E QY   Y  V
Sbjct: 117 CSAGVGRSGAFCAIDYCIDELRDLG---QVNVQGAVRKLRRQRAYAIQTEEQYVLCYRTV 173

Query: 567 LEFIET 572
           LE+ ++
Sbjct: 174 LEYAKS 179


>UniRef50_O82656 Cluster: Protein tyrosine phosphatase; n=9; core
           eudicotyledons|Rep: Protein tyrosine phosphatase -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 340

 Score =  114 bits (275), Expect = 5e-24
 Identities = 71/205 (34%), Positives = 106/205 (51%), Gaps = 12/205 (5%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGK-VKCERYWPDLNKTEVVKKYTI 427
           +IATQG L  T+  FW M+ Q+   II+M T+ ++  + VKC  Y+ D +        ++
Sbjct: 134 FIATQGPLPHTMEDFWEMVIQQHCPIIVMLTRLVDNNRTVKCGDYFQDEDGPREFGNISL 193

Query: 428 LNEFESSTP-DYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
             ++  +T     LR   V  K+      ++ H  +  WPDH VP +   V  IL     
Sbjct: 194 TTKWIKTTDTSLMLRNLEVNYKETEDQPMSVLHIQYPEWPDHGVPKDTVAVREILK---- 249

Query: 487 RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
           RL Q+     PP+   + VHCSAGIGRTGT+  I   + +I   G    +D+ +TV + R
Sbjct: 250 RLYQV-----PPSLGPIIVHCSAGIGRTGTYCAIHNTIQRI-LAGDMSALDLAKTVALFR 303

Query: 547 DQRSGMVQNEAQYKFIYMAVLEFIE 571
            QR GMVQ   QY F Y A+++ +E
Sbjct: 304 KQRIGMVQTMDQYFFCYNAIVDELE 328



 Score = 44.4 bits (100), Expect = 0.009
 Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 6/102 (5%)

Query: 174 QVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNR 233
           Q+ H H  +   + + + P +S+A++   +   +  +M  +  L +        N+ KNR
Sbjct: 37  QLNHCHQALGVFRGKIQNP-DSIAHE---FTGLQANRMWPSELLLNSTVAMNSVNVEKNR 92

Query: 234 YKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCDSMDSIS 275
           Y +++PFD  R++L         G  Y+NA+ I+    +SIS
Sbjct: 93  YSDVVPFDKNRIVLNPCKDSSAKG--YVNASLIKTSESESIS 132


>UniRef50_Q9VJ95 Cluster: CG7180-PA; n=8; Endopterygota|Rep:
           CG7180-PA - Drosophila melanogaster (Fruit fly)
          Length = 682

 Score =  114 bits (275), Expect = 5e-24
 Identities = 69/211 (32%), Positives = 111/211 (52%), Gaps = 19/211 (9%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY--- 425
           YI TQG +  T+  +W M+WQE++  I+M TK  +  KV C +YWP     EV ++Y   
Sbjct: 170 YIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPP--NMEVHEQYGDI 227

Query: 426 --TILNEFE-SSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
              I+ E + ++    T R + + +K E T +R I  FH+T W  H  P       N LL
Sbjct: 228 FINIVREEQLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCPFS-----NALL 282

Query: 483 DVNYRLQQIMTG---TDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIH 539
           +   R++ ++      +   +  + VHCS G GR+G ++ ID  L+   +E  +C  ++ 
Sbjct: 283 EFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEE--EC-FNVF 339

Query: 540 RTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
             ++ +R  R G+V+N  QYKFIY  + E I
Sbjct: 340 GYLKKLRQSRKGLVENVEQYKFIYDTLEEHI 370



 Score = 69.3 bits (162), Expect = 3e-10
 Identities = 52/218 (23%), Positives = 101/218 (46%), Gaps = 28/218 (12%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTE------ 420
           + YI T+  +  T+  FWS+++ ++   +++  +   + + +   +WP+ +K E      
Sbjct: 471 REYIVTEWPMKHTLGEFWSLVYDQECSAVVVLCQPPSQSQ-QYPSFWPNKSKMEKYGPVF 529

Query: 421 -----VVKKYTILN--EFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWP-DHRVPS 472
                + K YT +   EF+ +    +L   +   K  T   RT+  F  T WP  H+VPS
Sbjct: 530 SVHYVMSKSYTNIKQWEFKINKKIVSLTEMMAGVKAPT---RTVQLFQLTCWPMGHKVPS 586

Query: 473 EPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGF 532
               ++ ++  V     ++  G        VCV    G  R G +   +  ++Q+ + G 
Sbjct: 587 STNSLVYLMNMVEIWRNKVDYGP-------VCVVSPDGRSRAGVYCAANACIEQVIQHG- 638

Query: 533 DCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
             E+D+ + V+ VR  R  +V+N  +YK+ Y  VL ++
Sbjct: 639 --EVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYV 674



 Score = 39.9 bits (89), Expect = 0.19
 Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 2/42 (4%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           K  N+ KN+    IP+D+ RV+L+ +   G   SDY+NA+Y+
Sbjct: 122 KKNNLEKNQNPKCIPYDYNRVVLEKV--GGLQDSDYVNASYV 161


>UniRef50_P54637 Cluster: Tyrosine-protein phosphatase 3; n=2;
           Dictyostelium discoideum|Rep: Tyrosine-protein
           phosphatase 3 - Dictyostelium discoideum (Slime mold)
          Length = 989

 Score =  114 bits (274), Expect = 7e-24
 Identities = 80/247 (32%), Positives = 120/247 (48%), Gaps = 13/247 (5%)

Query: 357 NG-VPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD 415
           NG VP  + Y   YIA Q  L +TI  FW M+W+E   +I+  TK  E GK K + Y+P+
Sbjct: 505 NGEVPNSYRY---YIACQAPLPSTIKDFWRMVWEERSSVIVCLTKLEENGKKKADVYYPE 561

Query: 416 LNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPG 475
            ++ +    + I    +    D  +    + KK E    R +   H+T WPD   P    
Sbjct: 562 TSQAQEYGSFWIHLHKKVMFKDIGVSSLHLYKKGE-EFPREVVLLHYTQWPDCGAPPSSS 620

Query: 476 RVLNILLDVN-YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFD- 533
            +  + + VN ++ +     T+ P    V VHCSAGIGR+GTFI I++ + +I + G D 
Sbjct: 621 HIRTLSVMVNTFKARGSAKNTNGP----VIVHCSAGIGRSGTFISININMAKIERFGNDP 676

Query: 534 --CEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDSPRAR 591
               I I  +V  +R QR GMVQ   QY FI+  + + +     R    P   +     +
Sbjct: 677 SQMNISIKDSVLELRRQRRGMVQTLDQYIFIFKVINDVLTDMGIRSLSSPSKRRSCEMIK 736

Query: 592 SMPVPFL 598
           S P+P L
Sbjct: 737 STPMPRL 743



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 22/43 (51%), Positives = 27/43 (62%), Gaps = 5/43 (11%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPP-DGPPGSDYINANYI 266
           +P N  KNRY +++P + TRV L  I   DG    DYINANYI
Sbjct: 466 QPNNYGKNRYHDVLPNESTRVRLTPIESGDG----DYINANYI 504


>UniRef50_Q9Y1W8 Cluster: SPTPN8; n=1; Ephydatia fluviatilis|Rep:
           SPTPN8 - Ephydatia fluviatilis
          Length = 180

 Score =  113 bits (272), Expect = 1e-23
 Identities = 68/188 (36%), Positives = 107/188 (56%), Gaps = 18/188 (9%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWP--DLNKTEV-VKKYTILNEFESSTPDYTLRRFLV 445
           +++V II+M T E E G+ KC RY+P  D     V  ++Y I  +F +     T R F +
Sbjct: 1   EQNVSIILMLTSEQEEGQPKCHRYFPPDDQQGGHVQFEQYRITLKFVAQN-SVTTRCFSL 59

Query: 446 TKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCV 505
                  V R I H  ++ WPDH +P +P   L+ +  V+   QQ  +G        V V
Sbjct: 60  RHIPSNQV-REITHLQYSEWPDHGIPEDPQPFLDFVGTVHSLRQQYHSGVP------VLV 112

Query: 506 HCSAGIGRTGTFIVIDMILDQIRKEGFDC--EIDIHRTVQMVRDQRSGMVQNEAQYKFIY 563
           HCSAG+GR+G F+++D ++ ++     DC  EIDI +++Q++RDQR  +VQ   QYKF+Y
Sbjct: 113 HCSAGVGRSGVFVLMDFLMAKV-----DCGDEIDIAKSLQLLRDQRMNLVQMVGQYKFLY 167

Query: 564 MAVLEFIE 571
            A++ +I+
Sbjct: 168 SAIVHYIK 175


>UniRef50_UPI0000F203A3 Cluster: PREDICTED: similar to Ptpn23 protein;
            n=1; Danio rerio|Rep: PREDICTED: similar to Ptpn23
            protein - Danio rerio
          Length = 1273

 Score =  112 bits (270), Expect = 2e-23
 Identities = 70/218 (32%), Positives = 114/218 (52%), Gaps = 13/218 (5%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK- 423
            Y    IATQ  L+ T   FW M++++ V +I+M   E E  K K  RY+P     ++ + 
Sbjct: 854  YCPRLIATQAPLTGTAADFWLMVYEQKVSVIVMLVSEQELEKQKVLRYFPSERGQQLAQG 913

Query: 424  KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
              T+    + STP +  R   +  +D+ +++RT+ H  FT+WP+  +P     ++  + +
Sbjct: 914  PITLTLTTQKSTPTHIERMIGLQYRDQ-SLRRTVVHLQFTSWPELGLPESKSNLIRFIQE 972

Query: 484  V--NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRT 541
            V  +Y LQ+       P    V VHCS+G+GRTG F ++   L +I  E  +   D+ + 
Sbjct: 973  VHGHYLLQR-------PLHTPVVVHCSSGVGRTGAFCLLYAALQEI--EAGNGIPDLIQL 1023

Query: 542  VQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGL 579
            V+ +R QR  M+Q +   KF Y AVL+  E   QR G+
Sbjct: 1024 VRKMRQQRKNMLQEKLHLKFCYEAVLKHTEQVLQRHGI 1061


>UniRef50_Q9Y1X3 Cluster: SPTPR3; n=1; Ephydatia fluviatilis|Rep:
           SPTPR3 - Ephydatia fluviatilis
          Length = 183

 Score =  112 bits (270), Expect = 2e-23
 Identities = 63/181 (34%), Positives = 95/181 (52%), Gaps = 12/181 (6%)

Query: 392 VRIIIMTTKEIERGKVKCERYWPD-LNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDE 450
           ++ I+M TK  E GK+KCE YW D +         T+      S  D+ +R+F +  K  
Sbjct: 4   LQTIVMLTKCSEGGKIKCEMYWSDSMGGVYETDTLTVTTTSNESYADFQIRKFSIKCKVA 63

Query: 451 TTVK-RTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSA 509
                  + HFH+TAWPDH VP     +L+ +       +++    D      + VHCSA
Sbjct: 64  PDADCLQVTHFHYTAWPDHGVPQTATSILSFV-------RRVQNAHDKGKGVPLLVHCSA 116

Query: 510 GIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEF 569
           G+GRTGTFI +D +LD++R E     I +   V+ +R++R  M+Q  AQY  IY A  ++
Sbjct: 117 GVGRTGTFIALDTLLDRVRSE---TSISVFEIVKDMRNRRRFMIQTLAQYVLIYDAFDKY 173

Query: 570 I 570
           I
Sbjct: 174 I 174


>UniRef50_Q9NKZ8 Cluster: HgPTPN3 protein; n=1; Eptatretus
           burgeri|Rep: HgPTPN3 protein - Eptatretus burgeri
           (Inshore hagfish)
          Length = 379

 Score =  112 bits (269), Expect = 3e-23
 Identities = 61/182 (33%), Positives = 101/182 (55%), Gaps = 12/182 (6%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPD--YTLRRFLVT 446
           ++  R ++M  + +E+G VKCE+YWP +++ E+V          SS P   +T+ R L+ 
Sbjct: 1   EQQSRAVVMLNRVLEKGLVKCEQYWPTVDEPEMVFDTGYRLTLASSIPKEYFTISR-LML 59

Query: 447 KKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVH 506
           +   T  +R + HFH+T+WPD  VP  P   L  L+ V        +G   P+   + VH
Sbjct: 60  ECLSTAERREVLHFHYTSWPDFGVPDSPAAFLAFLMRVR------RSGVLDPSFGPIVVH 113

Query: 507 CSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAV 566
           CSAGIGR+GTF ++D  L      G   E D+++ +  +R  R G++Q  AQ +F ++A+
Sbjct: 114 CSAGIGRSGTFCLVDSCLALHAARG---EPDVYQVLLDLRRFRMGLIQTPAQLRFSFLAI 170

Query: 567 LE 568
           ++
Sbjct: 171 IQ 172


>UniRef50_Q5W3C2 Cluster: Protein tyrosine phosphatase; n=5;
           Bracovirus|Rep: Protein tyrosine phosphatase - Cotesia
           congregata bracovirus
          Length = 322

 Score =  112 bits (269), Expect = 3e-23
 Identities = 64/213 (30%), Positives = 106/213 (49%), Gaps = 11/213 (5%)

Query: 365 YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VK 423
           + K +I  +     T Y F+ M+W E V+II+M T++ E GK KC  YW ++ +T   + 
Sbjct: 90  HTKKFICGEAPTRNTCYDFYRMMWMEQVQIIVMLTQKKENGKEKCYPYWSNVEQTSFRLG 149

Query: 424 KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
           K+ I        P Y      +T  D T   +T+ HF+FTAWPDH VP      ++ +L+
Sbjct: 150 KFQITTINVEKFPHYVKSTLELT--DGTGATQTVIHFNFTAWPDHDVPKNTSEFVSFVLE 207

Query: 484 VNYRLQQ-----IMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
           V    ++     +  G        + VHC+AG+GRT  + V+D+ + +      +  + I
Sbjct: 208 VRQCQRELYENSLQNGHKRLQPPPIVVHCNAGLGRTPCYCVVDISISRFH---HNQTVSI 264

Query: 539 HRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
              V  +R++R   + N  QY F Y AV  +++
Sbjct: 265 PSIVSSIREKRYHSLFNPFQYFFCYEAVKFYLD 297



 Score = 35.1 bits (77), Expect = 5.4
 Identities = 21/51 (41%), Positives = 33/51 (64%), Gaps = 7/51 (13%)

Query: 219 DRMEGS---KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           +++EG+   + +N   NR+ + + FDH+RVIL   P +   GS YINANY+
Sbjct: 39  EKVEGTFTAEKKNKSLNRFDHAVCFDHSRVIL---PKERNRGS-YINANYV 85


>UniRef50_Q9NL09 Cluster: AmPTPN3 protein; n=1; Branchiostoma
           belcheri|Rep: AmPTPN3 protein - Branchiostoma belcheri
           (Amphioxus)
          Length = 331

 Score =  111 bits (268), Expect = 4e-23
 Identities = 64/193 (33%), Positives = 101/193 (52%), Gaps = 18/193 (9%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWP---------DLNKTEVVKKYTILNEFESSTPDYT 439
           ++  + ++M  + IE+G +KC +YWP         +L   E   K T+L E     P +T
Sbjct: 1   EQRTKAVVMLNRVIEKGTIKCAQYWPQGEVNGHSDELELEETGYKVTLLEE--DVRPYFT 58

Query: 440 LRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPA 499
           +R +L+ +  +T   R ++HFH+T WPD  VP  P   L+ LL+V      + +   PP 
Sbjct: 59  IRTYLLQRL-KTNESRKVFHFHYTRWPDFGVPESPAAFLHFLLEVRDS-GSLESDVGPPV 116

Query: 500 QAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQY 559
                VHCSAGIGR+G F ++D  L  + K      ++I R +  +R  R G++Q   Q 
Sbjct: 117 -----VHCSAGIGRSGVFCLVDTCLVLLDKTRDLTSLNIRRLLLDMRQYRMGLIQTPDQL 171

Query: 560 KFIYMAVLEFIET 572
           +F Y+AV+E   T
Sbjct: 172 RFSYLAVIEGART 184


>UniRef50_UPI0000E45C40 Cluster: PREDICTED: similar to receptor
            protein-tyrosine phosphatase 10d; n=5; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to receptor
            protein-tyrosine phosphatase 10d - Strongylocentrotus
            purpuratus
          Length = 2542

 Score =  111 bits (267), Expect = 5e-23
 Identities = 63/201 (31%), Positives = 98/201 (48%), Gaps = 11/201 (5%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
            K YIA+QG +  ++  FW M+++     I M T  +E GK KCE YWPD +        T
Sbjct: 2349 KEYIASQGPVPDSVNDFWEMVFENKSTTIAMITGLVEGGKTKCEHYWPDDDTPVNYGSVT 2408

Query: 427  ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNY 486
            +          +T+R FL+ K  +   +   + + F  W DH VP+    ++  +  ++ 
Sbjct: 2409 VTMTHTQEMEQWTVRSFLLEKGMQ---QFETHQYAFKGWVDHDVPNNARPMIEFIRTIDV 2465

Query: 487  RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVR 546
                 +          + VHCSAGIGRTG FI +  ++ Q+     +  ID+  TV  +R
Sbjct: 2466 AHDANL--------GPITVHCSAGIGRTGVFIALHKLIKQVETSKPNDYIDVCGTVARMR 2517

Query: 547  DQRSGMVQNEAQYKFIYMAVL 567
            +QR  MVQ   QY FI+  +L
Sbjct: 2518 EQRFNMVQTVKQYMFIHQCLL 2538



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 30/67 (44%), Positives = 41/67 (61%), Gaps = 4/67 (5%)

Query: 201  GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
            GF EE+ +L  +   +  D    +   N  KNRY+NI+PFD T V L+D+  +G   SDY
Sbjct: 2281 GFVEEYNSLSNVGRDKSTDASRLAV--NATKNRYRNILPFDETAVHLQDL-EEGQT-SDY 2336

Query: 261  INANYIR 267
            INANYI+
Sbjct: 2337 INANYIQ 2343


>UniRef50_Q9TZQ1 Cluster: Putative uncharacterized protein; n=5;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 398

 Score =  109 bits (262), Expect = 2e-22
 Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 19/215 (8%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEV-VKKY 425
           K +I  QG L  TI  FW M+ Q  V  I+M  K +E GK+KC +YWP     ++ +K  
Sbjct: 172 KRFICAQGPLDQTIDEFWWMVIQNKVEQIVMLCKTVEMGKLKCAQYWPAAQGEKLTLKSG 231

Query: 426 TILNEFESSTP---DYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
            ++     S P   D  ++  ++          ++ H  +T WPD  VP  P ++ ++  
Sbjct: 232 CVVENVSGSKPMERDPEIQITMLNLTYSGGQTMSVRHLQWTEWPDRGVP--PCKLTSL-- 287

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
                L   + G+  P    + VHCSAGIGRTGT + I+ IL++I  E   C   +   V
Sbjct: 288 ----ELLSAIRGSKVP----IVVHCSAGIGRTGTIVAIEYILEKI-AENKPCP-PMPELV 337

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLE-FIETEKQR 576
           + +RDQR+  +QN+ QY FI+  +L  F+E  K++
Sbjct: 338 KALRDQRAFSIQNDVQYLFIHRVMLNYFLEKYKEK 372


>UniRef50_UPI000155BF12 Cluster: PREDICTED: similar to protein
           tyrosine phosphatase, non-receptor type 18
           (brain-derived); n=1; Ornithorhynchus anatinus|Rep:
           PREDICTED: similar to protein tyrosine phosphatase,
           non-receptor type 18 (brain-derived) - Ornithorhynchus
           anatinus
          Length = 682

 Score =  108 bits (259), Expect = 5e-22
 Identities = 62/173 (35%), Positives = 85/173 (49%), Gaps = 12/173 (6%)

Query: 397 MTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESS-TPDYTLRRFLVTKKDETTVKR 455
           M   E E GK KCERYWP   +   +  ++++   E    PD  LR   VT + +T   R
Sbjct: 298 MAVMEFENGKKKCERYWPLEQEPLQIGPFSVVQTREKQLNPDVLLRSMTVTFQRDT---R 354

Query: 456 TIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTG 515
           T+  FH+ AWPD  +P   G  L+++ +          G DP   A +CVHCSAG GRTG
Sbjct: 355 TLSQFHYMAWPDRGIPDNTGHFLSMVEEARRT-----KGDDP---APLCVHCSAGCGRTG 406

Query: 516 TFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
               +D +   + K+       I   V  +R QR   VQ + QYKF+Y  V E
Sbjct: 407 VICTVDYVRHLLLKQRIPPNFSIFDIVLEMRRQRPSAVQTQEQYKFVYHIVAE 459


>UniRef50_Q4Q0M4 Cluster: Tyrosine specific protein phosphatase,
           putative; n=4; Leishmania|Rep: Tyrosine specific protein
           phosphatase, putative - Leishmania major
          Length = 493

 Score =  108 bits (259), Expect = 5e-22
 Identities = 68/224 (30%), Positives = 110/224 (49%), Gaps = 16/224 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
           YIATQ  +  ++  FW M+++ D   I+M     E GK+K E YWP       +   ++ 
Sbjct: 108 YIATQAPMKNSVLDFWRMVYENDSAFIVMLCAVKENGKIKSETYWPPRGAAYDMGVLSVT 167

Query: 429 NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
              E+  PD   RR L+  +     ++ +YH  + AWPD  VP     ++ ++       
Sbjct: 168 LVAENMRPDSVHRRLLL--RSVRGDEKEVYHMQYVAWPDQGVPQSSVTLMEMI------- 218

Query: 489 QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
              +  +    Q+ + VHCS GIGRTG FI + + L Q +       I+I   V+ ++  
Sbjct: 219 -NTIAKSPRSTQSPIVVHCSGGIGRTGVFIGLHIALAQFQLG--QANINIPCIVRHLKAC 275

Query: 549 RSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDSPRARS 592
           R+GMVQ + QY F+Y AV    + E +R+ L  +A  +   +RS
Sbjct: 276 RTGMVQRKDQYIFLYYAV----QREMERMLLSQKAGVNLLDSRS 315


>UniRef50_UPI00006CBB4B Cluster: Protein-tyrosine phosphatase
           containing protein; n=1; Tetrahymena thermophila
           SB210|Rep: Protein-tyrosine phosphatase containing
           protein - Tetrahymena thermophila SB210
          Length = 381

 Score =  107 bits (258), Expect = 6e-22
 Identities = 76/245 (31%), Positives = 128/245 (52%), Gaps = 36/245 (14%)

Query: 359 VPTVHVYN--KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD- 415
           + +VH  N  + +IATQG L  T   FW M+W E+V+ I+M     E  KV+C++YWP  
Sbjct: 114 INSVHKGNGERKFIATQGPLPETFNQFWKMVWSENVQCIMMLCNLRENDKVQCDQYWPSG 173

Query: 416 LNKTEVVKKYTI-LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEP 474
           +  T+   K ++   + E        R+  +TK +ET   R IY + ++ W DH +P E 
Sbjct: 174 VGVTQQYGKLSVNFEDEEIHFNSLYKRKMTLTKHNET---RVIYQYQWSEWKDHGIPDEN 230

Query: 475 G-RVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFI-VIDMILD------Q 526
              +++ L+D+      +++      +++  VHCSAG+GRTGT I +++++L+       
Sbjct: 231 SINIIDELIDI------MLSEYQQNRKSI--VHCSAGVGRTGTLISLVNLVLNLRHHLPT 282

Query: 527 IRK---EGF----------DCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETE 573
           I+    +G            C I I   V+ +R+QR GMV +  QY ++Y  +   IE E
Sbjct: 283 IKNAVMQGITNFHENEQLKKCTISIFGIVRRLREQRWGMVHHSEQYGYLYKYMKIIIERE 342

Query: 574 KQRVG 578
            Q++G
Sbjct: 343 LQKIG 347



 Score = 35.5 bits (78), Expect = 4.1
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 4/63 (6%)

Query: 205 EFETLQMMENLQLF-DRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
           EF  ++ +   Q   + ++  +P+  + NRY NI+P+  T V L++   D  P   YINA
Sbjct: 55  EFRLIRRITETQFHNEELKDYEPKLNKLNRYNNILPYKRTEVKLEEESDDECP---YINA 111

Query: 264 NYI 266
           ++I
Sbjct: 112 SFI 114


>UniRef50_UPI00006A1AD2 Cluster: Tyrosine-protein phosphatase
            non-receptor type 23 (EC 3.1.3.48) (His-
            domain-containing protein tyrosine phosphatase) (HD-PTP)
            (Protein tyrosine phosphatase TD14) (PTP-TD14).; n=2;
            Xenopus tropicalis|Rep: Tyrosine-protein phosphatase
            non-receptor type 23 (EC 3.1.3.48) (His-
            domain-containing protein tyrosine phosphatase) (HD-PTP)
            (Protein tyrosine phosphatase TD14) (PTP-TD14). - Xenopus
            tropicalis
          Length = 1652

 Score =  107 bits (258), Expect = 6e-22
 Identities = 69/216 (31%), Positives = 107/216 (49%), Gaps = 9/216 (4%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            Y  + IATQ  L  T   FW MI ++ V +I+M   E E  K K  RY+P      +V  
Sbjct: 1269 YCPSIIATQAPLVGTASDFWLMIHEQKVSLIVMLVSEQEIEKQKVLRYFPLERGQAMVHG 1328

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
            +  L        D  + R L  +  + ++KR+I H  FT+WP+  +P   G +L  + +V
Sbjct: 1329 HISLTLTSQKVTDIHVERVLSLQYKDQSLKRSIIHLQFTSWPELGLPDSKGNLLRFIQEV 1388

Query: 485  -NYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
             ++ L Q       P    + VHCS+G+GRTG F ++   + ++  E  +   D+   V+
Sbjct: 1389 HSHYLHQ------RPLHTPIVVHCSSGVGRTGAFCLMYAAMQEV--EAGNGIPDLAELVK 1440

Query: 544  MVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGL 579
             +R QR  M+Q +   KF Y AVL+  E   QR G+
Sbjct: 1441 KMRQQRKYMLQEKIHLKFCYEAVLKHAEQVLQRHGV 1476


>UniRef50_Q5I146 Cluster: PTP 2; n=1; Microplitis demolitor
           bracovirus|Rep: PTP 2 - Microplitis demolitor bracovirus
          Length = 325

 Score =  107 bits (258), Expect = 6e-22
 Identities = 74/225 (32%), Positives = 109/225 (48%), Gaps = 23/225 (10%)

Query: 365 YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV-K 423
           Y K +I TQ  L  T Y FW  +W    RII+M  K+ E  K +C  YW D+   ++V  
Sbjct: 90  YKKKFICTQAPLQQTAYDFWRTVWMHHTRIIVMMCKKKENRK-QCFAYWNDIEGGDIVFG 148

Query: 424 KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL- 482
           K+ I      +   Y     LVT  D T+  + + HF FT WPD+ VP++   +LN +L 
Sbjct: 149 KFKITTTQIETHLSYIETTLLVT--DGTSAIQEVTHFVFTQWPDYGVPNDVMNLLNFILT 206

Query: 483 ------DVNYRLQQ--IMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFD- 533
                 DV  +L Q     G +PP    + VHCSAG+GRTG + ++D  + +     FD 
Sbjct: 207 VKSAQKDVIRQLAQERFKIGDNPPP---IVVHCSAGVGRTGAYCLLDSAISE-----FDA 258

Query: 534 -CEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
              I I  T+  +R+QR   +    QY F Y  +  ++     +V
Sbjct: 259 CATISIPSTLINIRNQRYYCIFILPQYFFCYRVMERYVNLTVNKV 303



 Score = 41.5 bits (93), Expect = 0.062
 Identities = 23/45 (51%), Positives = 29/45 (64%), Gaps = 4/45 (8%)

Query: 222 EGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           E  K EN + NRY +++ FDHTRV L   P +   G DYINANY+
Sbjct: 45  ESMKLENRKLNRYLDMLCFDHTRVTL---PAEKNRG-DYINANYV 85


>UniRef50_Q9Y1X0 Cluster: SPTPR7; n=1; Ephydatia fluviatilis|Rep:
           SPTPR7 - Ephydatia fluviatilis
          Length = 179

 Score =  107 bits (258), Expect = 6e-22
 Identities = 59/185 (31%), Positives = 99/185 (53%), Gaps = 14/185 (7%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWPDLNKTE--VVKKYTILNEFESSTPDYTLRRFLVT 446
           + +V  I+M TK +E  K KC RYWP ++  E  V  +Y+I N FE S   YT+    ++
Sbjct: 1   ENNVPSIVMLTKLVENDKEKCSRYWPQVSSLEPDVYGQYSIRNNFEQSEASYTISYLTIS 60

Query: 447 -KKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCV 505
            +++  + ++ + H  +TAWPD  VP E   +L+    V+  L         PA     V
Sbjct: 61  MEQNGISREKDVVHLWYTAWPDFGVPKECNTILDFYNTVSVYLN--------PAAGPTVV 112

Query: 506 HCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMA 565
           HCSAG+GR+G FI I M + + ++      +D  + +  +R+ R G +Q   QY F++ A
Sbjct: 113 HCSAGVGRSGAFIAIHMGITEFKRMKI---VDPLKYLCSIREDRGGAIQTWEQYLFVHRA 169

Query: 566 VLEFI 570
           + +++
Sbjct: 170 LADYM 174


>UniRef50_UPI0000E49995 Cluster: PREDICTED: similar to Receptor-type
           tyrosine-protein phosphatase alpha precursor
           (Protein-tyrosine phosphatase alpha) (R-PTP-alpha); n=8;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Receptor-type tyrosine-protein phosphatase alpha
           precursor (Protein-tyrosine phosphatase alpha)
           (R-PTP-alpha) - Strongylocentrotus purpuratus
          Length = 1037

 Score =  107 bits (256), Expect = 1e-21
 Identities = 65/206 (31%), Positives = 105/206 (50%), Gaps = 12/206 (5%)

Query: 368 TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI 427
           T++ TQ  L TT+  FWS++       ++M   + +  K  C +YWPD N  +    Y++
Sbjct: 769 TFMTTQMPLPTTVSDFWSLVLNYKPSTVVMLNDKSQNDK-SCAQYWPDANSVQF-GSYSV 826

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
                SS  D T+R+  VT+  +T+   T Y FH   WP H   S+P      L+ +   
Sbjct: 827 STLSTSSDGDMTIRQLKVTRNSKTSHTVTQYQFH--GWPKHG--SDPQLGARSLMKL--- 879

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
           ++ + + T+   +  + VHC +G GRTG F      + QI  EG    +DI +TV+++R 
Sbjct: 880 IRAVKSSTNKMNEFSILVHCLSGAGRTGVFCTAMECIAQIA-EGDS--VDIFQTVKILRA 936

Query: 548 QRSGMVQNEAQYKFIYMAVLEFIETE 573
            R   VQ E +Y F+Y  + E++ TE
Sbjct: 937 DRMQFVQTEEEYAFVYDVIREYLHTE 962



 Score = 76.2 bits (179), Expect = 2e-12
 Identities = 44/114 (38%), Positives = 59/114 (51%), Gaps = 11/114 (9%)

Query: 455 RTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRT 514
           RT+  FHFT WPD  VP     +L  + +V     Q    T P     + +HCSAG+GRT
Sbjct: 569 RTVTQFHFTEWPDKGVPKHTSSLLKFIKEVKADHGQF---THP-----LIIHCSAGVGRT 620

Query: 515 GTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
           G  I ID ++   +       +D+   V  +R +R  MVQ + QY FIY AVLE
Sbjct: 621 GVVISIDSVVAHAKTTRM---VDVFNFVTNIRQKRPYMVQTQEQYAFIYGAVLE 671



 Score = 50.8 bits (116), Expect = 1e-04
 Identities = 47/142 (33%), Positives = 63/142 (44%), Gaps = 21/142 (14%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F EEF  L       ++ +    +  N  KNRYKNI+P+D  RV L+ I  D  P SDY 
Sbjct: 475 FSEEFHDLP---GPNIYPQTVAQEEINFTKNRYKNILPYDSARVKLEVI--DNNPHSDYF 529

Query: 262 NANYIRCDSMDS--ISDSQEFTGNGS-----TENGKDGTPSKAK-------DKSSPVHTS 307
           NA+YI     D   I+   +  G G        N  D   +  +       DK  P HTS
Sbjct: 530 NASYIPSFDNDKAYIASQGKKWGPGKMTKAFVSNAGDDYRTVTQFHFTEWPDKGVPKHTS 589

Query: 308 VIVTEEPVKSSKKVHGNGTHKL 329
            ++  + +K  K  HG  TH L
Sbjct: 590 SLL--KFIKEVKADHGQFTHPL 609



 Score = 37.5 bits (83), Expect = 1.0
 Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 12/98 (12%)

Query: 171 TRIQVRHFHTRVKQLQKENEGPIESMAYKQGFWEEFETLQMM-ENLQLFDRMEGSKPENI 229
           T I V HF   ++ L    +G   S   K     EF+TL+ +  +        G   +N 
Sbjct: 678 TLIPVVHFTDHLQDLHSSGDGRGRSKMTK-----EFQTLKSLCPDPPASHTRSGRTRDNH 732

Query: 230 RKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
            KNRY N +P    RVIL        P  DYINA+ ++
Sbjct: 733 PKNRYGNNLPLQRNRVILDS------PDHDYINASQMK 764


>UniRef50_Q4SQ75 Cluster: Chromosome 2 SCAF14534, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2
           SCAF14534, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1003

 Score =  107 bits (256), Expect = 1e-21
 Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 13/196 (6%)

Query: 359 VPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNK 418
           +P   + N+ YIA QG L  T   FW M W++   +++M T ++ERG++KC +YWP+ + 
Sbjct: 772 IPASSLINR-YIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRIKCHQYWPNPDS 830

Query: 419 TEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVL 478
                 +T+    E     + +R  +     +T  +R +    + AWPDH VP +    L
Sbjct: 831 ATNYGDFTVTCHNEEGNSAFLVRE-MTLMNAQTEQQRELTQIQYLAWPDHGVPDDSTDFL 889

Query: 479 NILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
           + +  V  +      G D P    + VHCSAGIGRTG  I ++  L  +        ++I
Sbjct: 890 DFVALVRSK----RAGQDQP----MVVHCSAGIGRTGVLITMETALCLMECGQPVYPLEI 941

Query: 539 HRTVQMVRDQRSGMVQ 554
            RT   +RDQR+ M+Q
Sbjct: 942 VRT---MRDQRAMMIQ 954



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 23/44 (52%), Positives = 29/44 (65%), Gaps = 7/44 (15%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           P+N+ KNRY++I P+D TRVILK          DYINANYI  +
Sbjct: 735 PQNVSKNRYRDISPYDATRVILKST-------DDYINANYINME 771


>UniRef50_Q9NL17 Cluster: AmPTPR3 protein; n=1; Branchiostoma
           belcheri|Rep: AmPTPR3 protein - Branchiostoma belcheri
           (Amphioxus)
          Length = 217

 Score =  106 bits (255), Expect = 1e-21
 Identities = 60/183 (32%), Positives = 94/183 (51%), Gaps = 14/183 (7%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKK 448
           +++ R+I+M T+  ERGK KCERYWP+  +        +    E+   D+T R F +   
Sbjct: 1   EQNSRVIVMLTQCWERGKPKCERYWPEDEEPVFYGDIVVKMLSENKEDDWTCREFELANN 60

Query: 449 DETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCS 508
             +   R +  + FT+WPDH VP +    L  +  V    + I  G  P       VHCS
Sbjct: 61  SHS---RCVRQYQFTSWPDHGVPEDTTSSLQFVRMVR---RNIGEGAGP-----TVVHCS 109

Query: 509 AGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
           AG+GR+GTFI +D +L  +       ++DI   V  +R  R  MVQ + QY FI+  +++
Sbjct: 110 AGVGRSGTFITLDRLLQHMEDHE---QVDIFGIVHQMRMHRVFMVQTQEQYIFIHQCIMD 166

Query: 569 FIE 571
            ++
Sbjct: 167 LLQ 169


>UniRef50_A0T008 Cluster: Protein tyrosine phosphatase; n=4;
           Bracovirus|Rep: Protein tyrosine phosphatase - Cotesia
           plutellae polydnavirus
          Length = 306

 Score =  105 bits (253), Expect = 3e-21
 Identities = 70/211 (33%), Positives = 103/211 (48%), Gaps = 7/211 (3%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYW-PDLNKTEVVKKY 425
           K +IATQG L+ T   FW ++WQ+   +I+M T     G  KC +YW    N +  +  +
Sbjct: 91  KKFIATQGPLANTAADFWRLVWQQCCYVIVMLTPTKVSGGEKCYQYWCARENGSLDIDDF 150

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSE-PGRV-LNILLD 483
            I     ++  +Y      VT K   T  R + HF  + W +   PS+ P  V    ++D
Sbjct: 151 RIKTLKVTARNNYVRTLIEVTDKSLKT-SRKLSHFQCSNWFEFNTPSDLPWFVHFTNMID 209

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
              R+   +     P    + VHCSAG+GRTGTF  +D+ L+Q+ K     EI I   V 
Sbjct: 210 RVRRVYMELLEPKDPLLCPIVVHCSAGVGRTGTFCAVDICLNQVVKTS---EICIPNVVF 266

Query: 544 MVRDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
            VR+QR   V +  QY FIY  +  F+  +K
Sbjct: 267 NVREQRYAGVMSFKQYSFIYEVLHYFLSVQK 297



 Score = 40.3 bits (90), Expect = 0.14
 Identities = 21/42 (50%), Positives = 29/42 (69%), Gaps = 5/42 (11%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           KPEN  KNRY +I  ++H+RV+L     D   GS+YI+AN+I
Sbjct: 48  KPENELKNRYSDIPCWEHSRVVL-----DTKEGSNYIHANWI 84


>UniRef50_Q22668 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 591

 Score =  105 bits (253), Expect = 3e-21
 Identities = 65/209 (31%), Positives = 104/209 (49%), Gaps = 16/209 (7%)

Query: 362 VHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPD-LNKTE 420
           V+  N  +I TQG  + T+  FW M+       I+M  + +E GK KC +Y+P+   +  
Sbjct: 184 VNGLNAPFILTQGATAATVIDFWRMVVHTKTAYIVMLCEVMEDGKAKCAQYYPEKAGEAM 243

Query: 421 VVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNI 480
               +TIL   E       ++R L  +  +   +  + H H  +WPD  VP+    +L +
Sbjct: 244 TFGAWTILCSLEDDKDANIIKRTLSVRNVDNGKEHILKHLHTKSWPDRCVPNSTMALLRM 303

Query: 481 LLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHR 540
           L  V        T + P     V VHCSAGIGRTGTF+ I+  L QI  +G   E+D+  
Sbjct: 304 LYIVR-------TASGP-----VTVHCSAGIGRTGTFVAIEACL-QILTDG--KELDLLG 348

Query: 541 TVQMVRDQRSGMVQNEAQYKFIYMAVLEF 569
           T + +R+ R+G +Q + QY  +   ++ +
Sbjct: 349 TCRALRNSRAGSIQVDIQYMALVQILINY 377



 Score = 36.7 bits (81), Expect = 1.8
 Identities = 21/39 (53%), Positives = 26/39 (66%), Gaps = 5/39 (12%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N  KNRYK+++  D TRVIL     DG  G DYI+ANY+
Sbjct: 151 NPTKNRYKDVVCNDITRVILS----DGGDG-DYIHANYV 184


>UniRef50_A2PZQ3 Cluster: GfV-B2-ORF1; n=3; Glypta fumiferanae
           ichnovirus|Rep: GfV-B2-ORF1 - Glypta fumiferanae
           ichnovirus
          Length = 330

 Score =  105 bits (252), Expect = 3e-21
 Identities = 66/208 (31%), Positives = 101/208 (48%), Gaps = 6/208 (2%)

Query: 365 YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
           +   +IATQ  +  TI  F +MIWQ    II++ T   E  +     YW        + K
Sbjct: 122 WKNKFIATQAPMPNTIIDFLNMIWQNRCPIIVVLTDICEDKESNMYSYWSTTKGVRKIGK 181

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
           YT++        +YT     V        +R+I  FH+T W  H +P      L ++ +V
Sbjct: 182 YTVMTTDIKQKKNYTKYSLEVENAMVMKERRSISLFHYTDWEIHGIPKYIKGFLKLISNV 241

Query: 485 NY-RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
           N  RL+ +   +D    + + VHC+AG+ RTGT+ VID+ LD     G   EI++  TV+
Sbjct: 242 NEDRLKNLEEPSD--ISSPIVVHCNAGVSRTGTYCVIDICLDDFSIFG---EINVLDTVR 296

Query: 544 MVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
            VR QR   V +  QY FI+  + E ++
Sbjct: 297 SVRAQRHSSVFSANQYAFIFETLKEAVK 324



 Score = 48.4 bits (110), Expect = 5e-04
 Identities = 23/39 (58%), Positives = 28/39 (71%)

Query: 228 NIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           N +KNRY+NI  +DHTRVIL    P G   SDYI+ANY+
Sbjct: 79  NKKKNRYENIPCWDHTRVILPMSGPAGCTDSDYIHANYV 117


>UniRef50_Q5AXJ8 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 685

 Score =  105 bits (252), Expect = 3e-21
 Identities = 72/254 (28%), Positives = 118/254 (46%), Gaps = 40/254 (15%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-----DLNKTE 420
           N+ YIATQ  +  T   FW +IW++D+R+++  T E+ERG+VKC  YW        +   
Sbjct: 433 NQHYIATQAPMPDTFNDFWRVIWEQDIRLVVSLTAEVERGQVKCHPYWKTGTYGQFHVNN 492

Query: 421 VVKKYTILNEFESSTPDYTLRRFLVTKKDETTV----------------KRTIYHFHFTA 464
             KKY  +   +S T D  + R      D  T+                 R +    +  
Sbjct: 493 FSKKYVPMVPTDSQTVDSVVERSSTDSSDNPTLIVRHFGLSHSGFPFEPLREVTQIQYAD 552

Query: 465 WPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDP-PAQAVVCVHCSAGIGRTGTFIVIDMI 523
           WPD    S+P  +L+++   + +++ +     P      V VHCSAG GRTGTF  +D +
Sbjct: 553 WPDFGTTSQPRHLLSLIEQCD-KVRNVAAKAAPGNPNRPVLVHCSAGCGRTGTFCTVDSV 611

Query: 524 LDQIRKE-----------GFD-----CEID-IHRTVQMVRDQRSGMVQNEAQYKFIYMAV 566
           LD ++++            FD      ++D + +T+   R QR  +VQN +Q+   Y ++
Sbjct: 612 LDVLKRQRAQPGGQHDGRPFDQLLGGGQLDLVAKTLSDFRTQRPSVVQNLSQFVLCYESI 671

Query: 567 LEFIETEKQRVGLG 580
           LE+   +  R   G
Sbjct: 672 LEWAVAQMPRESPG 685



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 21/39 (53%), Positives = 30/39 (76%), Gaps = 3/39 (7%)

Query: 231 KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCD 269
           KNRY +I P+DH+RV L DI P+G  G DY+NA+Y++ +
Sbjct: 395 KNRYNDIYPYDHSRVKLHDI-PNG--GCDYVNASYLKAE 430


>UniRef50_P34137 Cluster: Tyrosine-protein phosphatase 1; n=3;
           Dictyostelium discoideum|Rep: Tyrosine-protein
           phosphatase 1 - Dictyostelium discoideum (Slime mold)
          Length = 521

 Score =  105 bits (252), Expect = 3e-21
 Identities = 57/175 (32%), Positives = 88/175 (50%), Gaps = 17/175 (9%)

Query: 365 YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL-------- 416
           Y K +I TQG L  TI  FW M+W+   RII+M ++E E  ++KC+RYWP+         
Sbjct: 161 YPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGGEQFSI 220

Query: 417 --NKTEVVKKYTI--LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPS 472
             N  EV   Y++  +   +    +   R   +T + ET   R I  + +  WPDH +P 
Sbjct: 221 YGNGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGET---RDITQYQYEGWPDHNIPD 277

Query: 473 EPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQI 527
                  +L  +  R  QI+  +D      + VHCSAG+GRTGTF    +++ ++
Sbjct: 278 HTQPFRQLLHSITNRQNQIIPSSD--RNVPIIVHCSAGVGRTGTFCTAVIMMKKL 330



 Score = 59.3 bits (137), Expect = 3e-07
 Identities = 33/63 (52%), Positives = 39/63 (61%), Gaps = 4/63 (6%)

Query: 204 EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
           EEF  L+  E++   +  EG K  N  KNRY NI+P +HTRV LK I      GSDYINA
Sbjct: 99  EEFRLLE--ESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKI--QDKEGSDYINA 154

Query: 264 NYI 266
           NYI
Sbjct: 155 NYI 157


>UniRef50_Q9Y1X1 Cluster: SPTPN2; n=1; Ephydatia fluviatilis|Rep:
           SPTPN2 - Ephydatia fluviatilis
          Length = 837

 Score =  105 bits (251), Expect = 4e-21
 Identities = 66/206 (32%), Positives = 106/206 (51%), Gaps = 19/206 (9%)

Query: 389 QEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKK 448
           ++ V+ ++MTT  IE+   KCE+YWP+   T      T+    +     + L + L    
Sbjct: 1   EQRVKCVVMTTNIIEKDSKKCEKYWPEPGHTLRFGAITVSGIQQKQEEGFILSK-LTLAH 59

Query: 449 DETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQI-MTGTDPPAQAVVCVHC 507
           D    +  +YHFH+T WPD   P  P  V     + N  ++Q  +  ++ P    +  HC
Sbjct: 60  DSEPQQHQVYHFHYTLWPDFGSP--PSTV-----EFNALVKQFSLFSSNHP----ILAHC 108

Query: 508 SAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVL 567
           SAG+GRTG  + +   L +  K G   ++D+   V+ +R QR GM+Q   QY+F Y A+ 
Sbjct: 109 SAGLGRTGVLVAVHTAL-EYHKAGH--KVDLPAIVRRMRRQRGGMIQTPEQYQFCYQAIA 165

Query: 568 EFIETEK-QRVGLGPEAAQDSPRARS 592
           + + +++ QRVG  P     SP+ARS
Sbjct: 166 DTLVSKRLQRVGSEPSI--KSPQARS 189


>UniRef50_Q9H3S7 Cluster: Tyrosine-protein phosphatase non-receptor
            type 23; n=21; Euteleostomi|Rep: Tyrosine-protein
            phosphatase non-receptor type 23 - Homo sapiens (Human)
          Length = 1636

 Score =  105 bits (251), Expect = 4e-21
 Identities = 63/218 (28%), Positives = 107/218 (49%), Gaps = 9/218 (4%)

Query: 365  YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
            Y    +ATQ  L  T   FW M+ ++ V +I+M   E E  K K  RY+P      +V  
Sbjct: 1255 YCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHG 1314

Query: 425  YTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDV 484
               L      + +  + R L  +  + ++KR++ H HF  WP+  +P  P  +L  + +V
Sbjct: 1315 ALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEV 1374

Query: 485  N-YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
            + + L Q       P    + VHCS+G+GRTG F ++   + ++  E  +   ++ + V+
Sbjct: 1375 HAHYLHQ------RPLHTPIIVHCSSGVGRTGAFALLYAAVQEV--EAGNGIPELPQLVR 1426

Query: 544  MVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGP 581
             +R QR  M+Q +   +F Y AV+  +E   QR G+ P
Sbjct: 1427 RMRQQRKHMLQEKLHLRFCYEAVVRHVEQVLQRHGVPP 1464


>UniRef50_Q1DME1 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 809

 Score =  104 bits (250), Expect = 6e-21
 Identities = 77/254 (30%), Positives = 122/254 (48%), Gaps = 46/254 (18%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY 425
           NK YIATQ  L +T   FW ++W++D R+I+M T E E  ++KC  YW   +      + 
Sbjct: 554 NKLYIATQAPLPSTFKDFWHVVWEQDARLIVMLTAESEGLQLKCHPYWQ--SNAYGPFRV 611

Query: 426 TILNEF-------------------ESSTPD-----YTLRRFLVTKKDETTVK--RTIYH 459
           T++NE+                   ES+ P      Y + R L    +    +  R I  
Sbjct: 612 TLMNEYKVPLHVPPLSPNKRTHSRRESTGPSSFEELYMIVRHLTIIHESLPFEPLREITQ 671

Query: 460 FHFTAWPDHRVPSEPGRVLNILLDVNY-------RLQQIMTGTDPPAQAVVCVHCSAGIG 512
             ++ WPD   PS P  +L ++ + N        R  + +   +PP    + VHCSAG G
Sbjct: 672 IQYSHWPDFGTPSRPAHLLRVIEETNKFSNASNGRGPECIQDPEPPDPRKIVVHCSAGCG 731

Query: 513 RTGTFIVIDMILDQIRK-----EGFD-----CEID-IHRTVQMVRDQRSGMVQNEAQYKF 561
           RTGTF  ID ++D +++     EG D      ++D I  TV+  R QR  MVQ+  Q+  
Sbjct: 732 RTGTFCTIDSVIDMLKRQRRRGEGEDGWVYRDDLDLIASTVEDFRCQRLSMVQSLRQFVL 791

Query: 562 IYMAVLEFIETEKQ 575
            Y ++LE++ ++ +
Sbjct: 792 CYESILEWLASQPE 805



 Score = 35.9 bits (79), Expect = 3.1
 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 3/48 (6%)

Query: 227 ENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCDSMDSI 274
           E   KNRY NI P++H RV L           DY+NA+Y++    + +
Sbjct: 512 EQGNKNRYNNIYPYEHCRVRLGSTVQG---SCDYVNASYVKASRSNKL 556


>UniRef50_A3GI89 Cluster: Protein tyrosine phosphatase; n=1; Pichia
           stipitis|Rep: Protein tyrosine phosphatase - Pichia
           stipitis (Yeast)
          Length = 849

 Score =  104 bits (250), Expect = 6e-21
 Identities = 72/239 (30%), Positives = 106/239 (44%), Gaps = 12/239 (5%)

Query: 340 NPNYFNTTIPKSATETENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTT 399
           N +Y N   P    E   G+    + +  YIATQG +  T+  FW +I    + III  T
Sbjct: 592 NASYLN---PIQTVEGLTGLTPKFLKHLKYIATQGPMEETMGDFWKVIINLQIPIIISLT 648

Query: 400 KEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDY-TLRRFLVTKKDETTVKRTIY 458
            EIE G +KC  +W            T+  +   +  DY  +R F +T  D   V   + 
Sbjct: 649 DEIENGVMKCSPFWKSGVYKSNKSSITLRLQNSKTVNDYLIMRSFDMTMTD--AVHHKVL 706

Query: 459 HFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFI 518
                +WPD      P  ++ ++   +Y L  +  G +   +    +HCSAG GRTGT  
Sbjct: 707 QLQLLSWPDMGTVLTPVDIIQLIQLKSYLLDHLKLGEN--CEYPTAIHCSAGCGRTGTLC 764

Query: 519 VIDMILDQIRKEGFDCEI---DIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
            ID I++ I K     E+    ++  V   R QR  MVQN  QY  IY  +L ++   K
Sbjct: 765 TIDTIIN-ILKNNHSTELLYDPVYNIVNNFRKQRISMVQNLRQYFLIYEVLLHYLNNGK 822



 Score = 35.9 bits (79), Expect = 3.1
 Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 2/38 (5%)

Query: 231 KNRYKNIIPFDHTRVILKD--IPPDGPPGSDYINANYI 266
           KNRYK+I  ++H+RV L D  +  +     DYINA+Y+
Sbjct: 559 KNRYKDIFLYEHSRVKLNDSELEEEERDTEDYINASYL 596


>UniRef50_UPI00015B4244 Cluster: PREDICTED: similar to IP14232p;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           IP14232p - Nasonia vitripennis
          Length = 948

 Score =  103 bits (247), Expect = 1e-20
 Identities = 62/201 (30%), Positives = 97/201 (48%), Gaps = 16/201 (7%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTE---VV 422
           NK YI  Q  + +T+  FW MIW++  ++IIM T  +E G  KC  Y P L  ++   + 
Sbjct: 748 NKYYIGCQAPMESTVSDFWRMIWEQQCKVIIMLTDLVENGVEKCTEYIPPLEVSDCHRLY 807

Query: 423 KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
             Y +  +   +   Y +   L  K  E    R ++H  +  WP    P++   ++ +LL
Sbjct: 808 GDYQVTLKKREAKEKYAIST-LHLKNLENNTFREVFHIWY-LWPPSGTPTDATGLIAVLL 865

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
           +     + +  G   P    + VHCS G GRTGT I +D+    IR+      +D+ R V
Sbjct: 866 EA----RALQRGAAGP----IVVHCSPGTGRTGTLIALDL---GIRQYEITRTVDVPRVV 914

Query: 543 QMVRDQRSGMVQNEAQYKFIY 563
             +R  R+G VQ   QY F+Y
Sbjct: 915 YTIRRDRAGAVQTREQYAFVY 935



 Score = 41.1 bits (92), Expect = 0.082
 Identities = 22/52 (42%), Positives = 32/52 (61%), Gaps = 2/52 (3%)

Query: 216 QLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           Q+  +++   P    KNRY N+IP   TRV L+ +  D  P ++YINA+YIR
Sbjct: 693 QVSSKIDELPPGAELKNRYANVIPLPETRVPLQRLNND--PLTEYINASYIR 742


>UniRef50_A0D1T8 Cluster: Chromosome undetermined scaffold_34, whole
           genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_34,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 309

 Score =  103 bits (247), Expect = 1e-20
 Identities = 65/209 (31%), Positives = 104/209 (49%), Gaps = 15/209 (7%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           + YIATQG ++ ++  FW MIW  +V  IIM  K  +R +++CE+YWP         +  
Sbjct: 113 RKYIATQGPVNQSVQDFWHMIWTNNVGAIIMLCKLFDRQRIQCEKYWPSEKAIYGPYQID 172

Query: 427 ILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPG-RVLNILLDVN 485
            ++  ES+   +     + TK+ +  V     H+ +  WPD  +  E   +VL+ L  + 
Sbjct: 173 TISRQESNKDIFESSLIMKTKEKQHKVS----HYQWCDWPDFGIVKEDSYQVLDWLAGIA 228

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
               Q       P      +HCSAG+GRTGTF+ I  I   + K   D +I I   V+ +
Sbjct: 229 NEAAQ---DNKTPV-----IHCSAGVGRTGTFLAICHIKQLLIKN--DAQISIFSIVRRL 278

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
           R+QR  +VQ+  QY+ IY   +  ++  K
Sbjct: 279 REQRPLLVQSVQQYEMIYKYTIWLLKNLK 307



 Score = 34.7 bits (76), Expect = 7.1
 Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 3/63 (4%)

Query: 205 EFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINAN 264
           EF  L+ +   +  DR+     +    NRY +I+P+ H+  I+K    D    S YINAN
Sbjct: 47  EFSFLKQITQTREHDRLLYRSAQIQHLNRYADILPYVHS--IVKP-QLDTSDNSYYINAN 103

Query: 265 YIR 267
           YIR
Sbjct: 104 YIR 106


>UniRef50_UPI0000DB775F Cluster: PREDICTED: similar to CG14714-PA;
            n=2; Apis mellifera|Rep: PREDICTED: similar to CG14714-PA
            - Apis mellifera
          Length = 1397

 Score =  103 bits (246), Expect = 2e-20
 Identities = 65/203 (32%), Positives = 102/203 (50%), Gaps = 16/203 (7%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY- 425
            K YIA Q  + +T+  FW MIW++  ++IIM T  +E G  KC  Y P    T+  + Y 
Sbjct: 1193 KYYIACQAPMESTVTDFWRMIWEQQSKVIIMLTDLVENGVEKCTEYIPPSEVTDCRRLYG 1252

Query: 426  --TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
               +  +   +   Y +    +   ++ T  R +YH  +  WP + V S+   ++ +LL+
Sbjct: 1253 DFQVTLKKRETKEKYAISTLHLNNLEKNTF-REVYHIWY-LWPVNGVQSDGAGLIAVLLE 1310

Query: 484  VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
                LQ+   G  P     + VHCS G GRTGT I +D+    IR+      +D+ R V 
Sbjct: 1311 AR-ALQR--GGPGP-----IVVHCSPGTGRTGTLIALDL---GIRQYEITRTVDVPRVVY 1359

Query: 544  MVRDQRSGMVQNEAQYKFIYMAV 566
             +R  R+G V+ + QY FIY A+
Sbjct: 1360 TIRRDRAGAVKTKEQYAFIYKAL 1382



 Score = 42.7 bits (96), Expect = 0.027
 Identities = 19/37 (51%), Positives = 27/37 (72%), Gaps = 2/37 (5%)

Query: 231  KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
            KNRY N+IP   TRV+L+ +  D  P ++YINA+Y+R
Sbjct: 1152 KNRYANVIPLPETRVLLQKVNND--PLTEYINASYVR 1186


>UniRef50_O01557 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 363

 Score =  103 bits (246), Expect = 2e-20
 Identities = 70/216 (32%), Positives = 101/216 (46%), Gaps = 21/216 (9%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-----DLNKTEV 421
           K +I  QG L  T + FW+M  QE V  +IM    IE GK+KC +YWP      L   E 
Sbjct: 134 KKFICAQGPLENTQHSFWAMAIQEKVECVIMLCNCIETGKIKCHQYWPLEQGQKLVFGEA 193

Query: 422 VKKYTILN-EFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNI 480
               ++ N   +   PD         K D     RTI H  +  WPD  VP      +N+
Sbjct: 194 PNTISVANLGAKKMAPDEQCINVTTLKVDWGQGSRTIQHLQWENWPDRGVPQTNLTAINL 253

Query: 481 LLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHR 540
           L            G   P    + VHCSAGIGRTGT + I  + D++   G +C + ++ 
Sbjct: 254 L--------SATRGNQNP----ILVHCSAGIGRTGTIVAIAYVQDKM-MAGENC-MAMNE 299

Query: 541 TVQMVRDQRSGMVQNEAQYKFIYMAVLE-FIETEKQ 575
            ++ +R  R   +QNE QY +++  +L  F+E  K+
Sbjct: 300 LIKELRSHRPWSIQNEFQYLYLHRVLLSYFLERYKE 335


>UniRef50_Q6BYA8 Cluster: Debaryomyces hansenii chromosome A of
           strain CBS767 of Debaryomyces hansenii; n=1;
           Debaryomyces hansenii|Rep: Debaryomyces hansenii
           chromosome A of strain CBS767 of Debaryomyces hansenii -
           Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
          Length = 352

 Score =  103 bits (246), Expect = 2e-20
 Identities = 76/224 (33%), Positives = 111/224 (49%), Gaps = 33/224 (14%)

Query: 369 YIATQGCLSTTIYPFWSMIWQE------DVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
           YIA QG L  TI+ FWSM + E      D  II M T   E G  KC +YWP   KT  V
Sbjct: 134 YIAAQGPLEATIHHFWSMCYNESEKQKNDTVIIAMVTPLTEGGMKKCSQYWP--TKTNPV 191

Query: 423 KKYTILNEFES-STPDYTLR----------RFLVTK---KDETTVKRTIYHFHFTAWPDH 468
              T L + +    P  T+            +L+T+   + +T VK+ +YHF++  W D 
Sbjct: 192 LNVTTLLQGDGIEIPGLTVHFVSETYIEKGDYLLTEMELRSKTQVKK-VYHFYYYKWADA 250

Query: 469 RVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIR 528
           RVP     ++++  ++    + +   T+ P   V  VHCSAG+GRTGTFI +D + +++ 
Sbjct: 251 RVPPSVSPLISLSQEIRALKKSV---TNEP---VPIVHCSAGVGRTGTFIALDQLFNELS 304

Query: 529 KEGFDCEID----IHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
            +  D   D    I   V  +R +R  MVQ   QY F+Y  + E
Sbjct: 305 PDILDPANDQFDPIEAIVTQLRSERMMMVQTVYQYCFLYDTMRE 348



 Score = 35.1 bits (77), Expect = 5.4
 Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 4/40 (10%)

Query: 227 ENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           +++++NRY N+ P++ +RV L    P     SDYINA+YI
Sbjct: 91  KSVQRNRYSNVFPWNKSRVKL----PVEQGHSDYINASYI 126


>UniRef50_Q2QX07 Cluster: Protein-tyrosine phosphatase containing
           protein, expressed; n=3; Oryza sativa|Rep:
           Protein-tyrosine phosphatase containing protein,
           expressed - Oryza sativa subsp. japonica (Rice)
          Length = 328

 Score =  102 bits (245), Expect = 2e-20
 Identities = 63/201 (31%), Positives = 101/201 (50%), Gaps = 16/201 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI- 427
           +I+TQG L+ T   FW M+++    +I+M T   +   +KC+ Y P   + E   KY + 
Sbjct: 133 FISTQGPLAKTFDDFWEMVYEYQCPVIVMLT---QFDSLKCDEYLPLRKQREAYGKYNVK 189

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
           +   +  +    LR  +V   + + V  ++ H  +  WPDH VP+    V  I       
Sbjct: 190 ITNAKRDSHQLWLRDVMVQCNESSRV-HSVRHIEYPDWPDHGVPTNTDAVRQI------- 241

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
            ++ +  T  P +  + VHCSAGIGRTG +I I   ++++   G      +  TV+ +R 
Sbjct: 242 -RKWLQNT--PMEHPIVVHCSAGIGRTGAYITIHSTIERLLL-GDKSSYHLDETVKTLRT 297

Query: 548 QRSGMVQNEAQYKFIYMAVLE 568
           QR GMVQ E QY F Y A+ +
Sbjct: 298 QRVGMVQTEKQYMFCYRAIAD 318



 Score = 46.8 bits (106), Expect = 0.002
 Identities = 24/64 (37%), Positives = 34/64 (53%)

Query: 204 EEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINA 263
           +EF  LQ   +  +    E     N  KNRY +++PFD TRV LK         +DYINA
Sbjct: 60  DEFRRLQDTRHELMRSSNEARNAANREKNRYIDVVPFDTTRVRLKRSTTSQTSSNDYINA 119

Query: 264 NYIR 267
           ++I+
Sbjct: 120 SFIK 123


>UniRef50_P91498 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 355

 Score =  102 bits (245), Expect = 2e-20
 Identities = 64/209 (30%), Positives = 104/209 (49%), Gaps = 19/209 (9%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV---KKY 425
           +I TQG    T+  F+ +IWQE    ++M    +E GK KCE+YWP+    +++    K 
Sbjct: 141 FICTQGPTEKTVDDFYRLIWQEKAPCVVMLCNIMECGKKKCEQYWPETADGQMILMDGKL 200

Query: 426 TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
           T+     +   +  +    +T  D+        H+ + AWPD  VP  P  V  +L+   
Sbjct: 201 TVKIAEPAKEVEQNILLMKITVIDDKGTSHNFEHWQWKAWPDRGVPELPMAVFRLLI--- 257

Query: 486 YRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMV 545
            RL+     T  P    + VHCSAGIGRTG+ + +++ L +        ++ +   V+ +
Sbjct: 258 -RLK-----TASP----IVVHCSAGIGRTGSIVGLEIALVKFCAGE---KVVLKDIVKEI 304

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
           R+QR G VQ +AQY F++  +L   E  K
Sbjct: 305 RNQRHGSVQTDAQYLFMHRVLLALAENRK 333



 Score = 40.7 bits (91), Expect = 0.11
 Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 3/48 (6%)

Query: 231 KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCDSMDSISDSQ 278
           KNRYK++   D TRV+LK  P D P  SDYI+AN+++ +  +    +Q
Sbjct: 101 KNRYKDVYCIDDTRVVLK-WPEDSP--SDYIHANWVKINGANKFICTQ 145


>UniRef50_Q4TC71 Cluster: Chromosome undetermined SCAF7048, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7048,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 516

 Score =  102 bits (244), Expect = 3e-20
 Identities = 71/233 (30%), Positives = 108/233 (46%), Gaps = 37/233 (15%)

Query: 357 NGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKV--------- 407
           N +   H   + +IATQG +  T+  FW M WQE+  II+M TK  E+ +V         
Sbjct: 293 NYIRGYHGDERAFIATQGPMVNTVNDFWQMAWQEESPIIVMITKLKEKNEVSASSSSSSS 352

Query: 408 --------------KCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTV 453
                         KC  YWP+  K  +  K  +L         YT R   +   ++T  
Sbjct: 353 SPPMTAPSPSLSLQKCVLYWPE--KRGIYGKVEVLVSGLRECEHYTTRSLTLKCGNQT-- 408

Query: 454 KRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGR 513
            R + H+ +T+WPDH+ P     +L ++ +V    +         A+  V VHCSAGIGR
Sbjct: 409 -RVLQHYWYTSWPDHKTPDSTLPLLQLMAEVEADRRAAA------ARGPVIVHCSAGIGR 461

Query: 514 TGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAV 566
           TG FI   +   Q++ EG    +D+      +R  R GM+Q   QY+F++ A+
Sbjct: 462 TGCFIATTIGCQQLQAEGV---VDMLSITCQLRADRGGMIQTGEQYEFVHHAL 511


>UniRef50_A2PZT3 Cluster: GfV-B36-ORF1; n=1; Glypta fumiferanae
           ichnovirus|Rep: GfV-B36-ORF1 - Glypta fumiferanae
           ichnovirus
          Length = 313

 Score =  102 bits (244), Expect = 3e-20
 Identities = 67/231 (29%), Positives = 112/231 (48%), Gaps = 13/231 (5%)

Query: 349 PKSATETEN---GVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERG 405
           P ++T+T+       T + + +  IATQ  +  T+  F++MIWQ D RII++ T+  E G
Sbjct: 90  PAASTQTDYIHANYVTNYKFKQKLIATQSPMPETMIDFFNMIWQNDCRIIVVLTEVFENG 149

Query: 406 KVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETT--VKRTIYHFHFT 463
             + + YW          KY ++        DY  +++ +  ++ET    +R +  +H+T
Sbjct: 150 VFEIDPYWCTKMGDRKHGKYRVMTSRIDDKGDY--KKYYLEIRNETVPEERRIVRLYHYT 207

Query: 464 AWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMI 523
            WP   +P     +L ++  VN   + +    + P    + VH  AG+GRTGT   ID+ 
Sbjct: 208 MWPAQGIPKNKVGILALVAAVN--SEMLYRRLEVPRMGPIVVHGDAGVGRTGTLCAIDIC 265

Query: 524 LDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
            +Q  K      +DI  TV  +R +R   V    QY FI+  VL+ + T K
Sbjct: 266 FEQWTKTQ---RLDILNTVIRLRTERHSSVTTAEQYIFIF-RVLKVLVTTK 312



 Score = 41.1 bits (92), Expect = 0.082
 Identities = 19/43 (44%), Positives = 28/43 (65%)

Query: 224 SKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           +KP N  +NRY++I  +D TRV L +  P     +DYI+ANY+
Sbjct: 62  NKPANRMRNRYEDIPCWDLTRVKLSNFGPAASTQTDYIHANYV 104


>UniRef50_Q8IG13 Cluster: Clear protein 1, isoform b; n=6;
            Caenorhabditis|Rep: Clear protein 1, isoform b -
            Caenorhabditis elegans
          Length = 1444

 Score =  102 bits (244), Expect = 3e-20
 Identities = 77/230 (33%), Positives = 114/230 (49%), Gaps = 42/230 (18%)

Query: 367  KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKY- 425
            K +IA Q  +  TI  FW M+W+++  +I+M     E+ + +C +YWPD    E + +Y 
Sbjct: 893  KLFIAAQAPVDATIGDFWRMVWEQESYLIVMVANLTEKNRQQCAKYWPD----EQITRYG 948

Query: 426  TILNEFESST--PDYTLRRFLVTKKDET-----------------TVK-------RTIYH 459
             I+ E  S +   DY +R F +    E                   VK       R I  
Sbjct: 949  DIIVEPASFSFHSDYAIRAFDIAHIGECGPDVIPNGNGVEYANVPIVKGQFANNSRRILQ 1008

Query: 460  FHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIV 519
            +HFT W D++ P     +L  +    YRL+++    + P    V +HCSAG+GRTGTFI 
Sbjct: 1009 YHFTNWNDYKAPECSTGLLRFM----YRLRELPQFNNSP----VVIHCSAGVGRTGTFIS 1060

Query: 520  IDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEF 569
            ID +LDQ   E    + +I   V  +R QR+ MVQ+  QY FIY A+ E+
Sbjct: 1061 IDSMLDQCLAED---KANIFEFVCNLRRQRNLMVQSLEQYVFIYKALAEW 1107



 Score = 77.0 bits (181), Expect = 1e-12
 Identities = 59/212 (27%), Positives = 101/212 (47%), Gaps = 20/212 (9%)

Query: 369  YIATQGCLST-TIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVV---- 422
            YIA Q  +S  T + FW MI  ++V  ++M + E +   V  E+YWP D + TE      
Sbjct: 1238 YIAAQDPVSEGTAFDFWRMIADQNVTTVVMLSDETDWSDV--EKYWPIDGSGTECHFGSE 1295

Query: 423  -KKYTILNEFESSTPDYTLRRFLVTKKDETTV--KRTIYHFHFTAWP-DHRVPSEPGRVL 478
                 +    E    D+ +R    + KD  ++   + +  + +T WP D  VP     ++
Sbjct: 1296 RNSVNVTCVSEEHHQDFIIRNLSYSMKDNESMPANQEVVQYSYTGWPSDSIVPKSANSLM 1355

Query: 479  NILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
            N++  V  R   +M      +QA + VHC  G   +G FI I ++   +R++  +  ID+
Sbjct: 1356 NLIEMVLQRQSSLMG-----SQAPIVVHCRNGSSESGIFICISLLW--LRQKA-EQRIDV 1407

Query: 539  HRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
             +TV+ ++  R  M     QY F Y A+ ++I
Sbjct: 1408 FQTVKGLQSHRPMMFTRFEQYSFCYRALADYI 1439



 Score = 49.6 bits (113), Expect = 2e-04
 Identities = 31/66 (46%), Positives = 42/66 (63%), Gaps = 6/66 (9%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F +E+E+L    + QL D +  ++ EN  KNRY +I  FD TRV LK I  +G   SDYI
Sbjct: 828 FAQEYESLP---HFQL-DTVASNRKENAIKNRYNDIRAFDDTRVKLKKI--NGDDYSDYI 881

Query: 262 NANYIR 267
           NAN+I+
Sbjct: 882 NANFIK 887



 Score = 47.2 bits (107), Expect = 0.001
 Identities = 30/75 (40%), Positives = 40/75 (53%), Gaps = 3/75 (4%)

Query: 201  GFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDY 260
            G  EEF+ L+      L      +K EN+ KNRY+  +PFD  RVIL   P  G   S Y
Sbjct: 1169 GLEEEFKKLERNLTTPLSSNF-AAKDENLLKNRYEAAVPFDKYRVILP--PTIGHADSSY 1225

Query: 261  INANYIRCDSMDSIS 275
            INA++I+    D I+
Sbjct: 1226 INASHIKGYFFDYIA 1240


>UniRef50_UPI00015603C7 Cluster: PREDICTED: similar to Ptpn21 protein;
            n=1; Equus caballus|Rep: PREDICTED: similar to Ptpn21
            protein - Equus caballus
          Length = 1141

 Score =  101 bits (243), Expect = 4e-20
 Identities = 55/160 (34%), Positives = 85/160 (53%), Gaps = 5/160 (3%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDL---NKTEVVKKY 425
            YIATQG L  T   FW M+W++ V II M T E E G+ K  RYWP L   + T    ++
Sbjct: 904  YIATQGPLQNTCQDFWQMVWEQGVAIIAMVTAEEEGGREKSFRYWPRLGSRHNTVTYGRF 963

Query: 426  TILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVN 485
             I   F + +  Y     L  K   T  +RT++H  +T WP+H  P +    L+ L ++ 
Sbjct: 964  KITTRFRTDSGCYATTG-LKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSYLEEIQ 1022

Query: 486  YRLQQIMTGTDPPA-QAVVCVHCSAGIGRTGTFIVIDMIL 524
               +   + ++P +    + VHCSAG+GRTG  I+ ++++
Sbjct: 1023 SVRRHTNSTSEPKSPNPPLLVHCSAGVGRTGVVILSEIMI 1062



 Score = 37.1 bits (82), Expect = 1.3
 Identities = 15/42 (35%), Positives = 28/42 (66%), Gaps = 3/42 (7%)

Query: 226 PENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           PEN  +NR+++++P+D  RV   ++ P     + YINA++I+
Sbjct: 856 PENAERNRFQDVLPYDDARV---ELVPTKENNTGYINASHIK 894


>UniRef50_UPI0000E464A3 Cluster: PREDICTED: similar to protein
           tyrosine phosphatase, receptor type, R, partial; n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           protein tyrosine phosphatase, receptor type, R, partial
           - Strongylocentrotus purpuratus
          Length = 176

 Score =  101 bits (243), Expect = 4e-20
 Identities = 61/182 (33%), Positives = 94/182 (51%), Gaps = 15/182 (8%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
           ++ATQG ++ T+  FW MIW  +  +I+M TK  ER + KCE YWP            + 
Sbjct: 9   FVATQGPMAHTLADFWRMIWFTNAPVIVMVTKIKERKRSKCEMYWP--QGQGFYGDIDVT 66

Query: 429 NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
            E      DY L+ F +   +E    R + H+ +TAWPD++ P  P  +L ++ +V +  
Sbjct: 67  VEETVPKDDYILKIFTLKYLNEC---RQVLHYWYTAWPDNKPPENPVTLLEMIREVEF-- 121

Query: 489 QQIMTGTDPP-AQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
               +  DP   +  V VHCSAG+GRTG +I I + + Q+ +E     +DI   V  +R 
Sbjct: 122 ----SRIDPTLPRGPVIVHCSAGLGRTGCYIAITLGMRQMDEESM---VDILGIVCQIRQ 174

Query: 548 QR 549
            R
Sbjct: 175 DR 176


>UniRef50_P91568 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 483

 Score =  101 bits (243), Expect = 4e-20
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 18/211 (8%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKY 425
           + +I TQ  L+ TI  FW MI    +  I+M  + +E+GK K   Y+P  + +T  + + 
Sbjct: 262 RRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRL 321

Query: 426 TILNEFESSTPDYTL--RRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
             + +      D TL      ++K  +  V + + H H+  WPDH VP       N L  
Sbjct: 322 CTVTKESRVDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPD------NFLSP 375

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
             +RL  ++     P    + VHCSAG+GRTGT  +I +IL+ I    F   I + R + 
Sbjct: 376 --FRLLTVVKNCTKP----IVVHCSAGVGRTGTLALILIILESICLPDF---IGVPRLLA 426

Query: 544 MVRDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
            +R++R   VQ E QY + +  VLE++  +K
Sbjct: 427 KLREERFRAVQTEMQYLYAHRCVLEYLALKK 457


>UniRef50_A5DFA6 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 310

 Score =  101 bits (242), Expect = 5e-20
 Identities = 77/225 (34%), Positives = 117/225 (52%), Gaps = 32/225 (14%)

Query: 369 YIATQGCLSTTIYPFWSMIWQE------DVRIIIMTTKEIERGKVKCERYWPD------- 415
           YIA+QG +  TI+ FW+M +Q+      D  I+ M T  +E G  KC +YWPD       
Sbjct: 93  YIASQGPMPATIHHFWAMCFQQSELQHNDTIIVAMVTPLVENGMTKCCKYWPDEHEPIMY 152

Query: 416 ----LNKTEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKR--TIYHFHFTAWPDHR 469
               L++    +K T+  E+ S + D     FLV+K    T ++  T++H++++ W D R
Sbjct: 153 LTNDLHRDGFTEKLTL--EYNSLSWDDE-GGFLVSKFTLLTPQKSKTVHHYYYSKWVDSR 209

Query: 470 VPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRK 529
            P    R L + L    RL Q    +  P + +  +HCSAG+GRTGT+I +D +L  ++ 
Sbjct: 210 SPPS-ARPL-VTLSRRIRLLQ----STVPNRPIPIIHCSAGVGRTGTYITVDHLLHHVQS 263

Query: 530 EGFDCEID---IHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
              + E D   I  TV  +R QR  MVQ   QY+F+Y  V   +E
Sbjct: 264 V-INPENDRDPILDTVTKLRQQRMMMVQTLHQYEFLYDTVKLMVE 307



 Score = 43.6 bits (98), Expect = 0.015
 Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 4/57 (7%)

Query: 222 EGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCDSMDSISDSQ 278
           + S P N  +NRY N+ P++  RV LK +    P  SDYINA++I  DS      SQ
Sbjct: 45  DASAPRNASRNRYINVFPWNFNRVHLKVL----PNYSDYINASHIEIDSSSRYIASQ 97


>UniRef50_UPI0000E49FA3 Cluster: PREDICTED: similar to RE52018p,
           partial; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to RE52018p, partial -
           Strongylocentrotus purpuratus
          Length = 908

 Score =  100 bits (240), Expect = 1e-19
 Identities = 93/382 (24%), Positives = 167/382 (43%), Gaps = 40/382 (10%)

Query: 202 FWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYI 261
           F EE++ ++++   Q    +   +  N  KNR+ NI+P++H+RV L  +  D        
Sbjct: 518 FTEEYDEIRLVGKDQAI--VSALEMVNRAKNRFTNILPYEHSRVKLAALADDS------- 568

Query: 262 NANYIRCDSMDSISDSQEFTG-NGSTENGKDGTPSKAKDKSSPVHTSVIVTEEPVKSSKK 320
           + +YI  + +   +  +EF    G      D       +K + +   V++T+   K   K
Sbjct: 569 DTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSI--IVMLTQLVEKGKIK 626

Query: 321 VHGNGTHKL-PAFEPSV---LRPNPNYFNTTIPKSATETENGVPTVHVYNKTYIATQGCL 376
            H        P    S+   ++    Y +  I + +    + +  +  Y+       G  
Sbjct: 627 CHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVP 686

Query: 377 STTIYPFWSMI-WQEDVRIIIMTTKE-------IERGKVKCERYWPDLNKTEVVKKYTIL 428
             T    W+M+ +   VR  I  T            G +KC  YWP            + 
Sbjct: 687 EKT----WTMLDFVRTVREAIQKTASDRPIVAHCSAGAIKCHEYWPADYNPVTYGSIQVS 742

Query: 429 NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRL 488
            +       + +R F +++ DE    R +  +HF +WPDH VP +   +L+ +  V   +
Sbjct: 743 VQALQQYDHWVIREFSISQGDEI---RKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAI 799

Query: 489 QQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQ 548
           Q+  T +D P    +  HCSAG+GRTGT+I +D ++  +++  +   IDI   +  +R Q
Sbjct: 800 QK--TASDRP----IVAHCSAGVGRTGTYIALDRLMQAMQENDY---IDIFGIICEMRMQ 850

Query: 549 RSGMVQNEAQYKFIYMAVLEFI 570
           R+ MVQ E QY FI+  V++ +
Sbjct: 851 RNHMVQTEKQYIFIHECVMDLL 872


>UniRef50_Q5I141 Cluster: PTP 1; n=1; Microplitis demolitor
           bracovirus|Rep: PTP 1 - Microplitis demolitor bracovirus
          Length = 300

 Score =  100 bits (240), Expect = 1e-19
 Identities = 63/212 (29%), Positives = 102/212 (48%), Gaps = 8/212 (3%)

Query: 363 HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
           H   + +I TQG L  T   FW  ++Q+ VR+I+M TK  E  K KC  YW    ++ V 
Sbjct: 88  HNMKRRFICTQGPLEETALDFWQAVYQDRVRVIVMITKTYEDNKQKCYPYWMTHERSTVT 147

Query: 423 -KKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL 481
             +  I  +   S  +Y +    +T  +  TV   I HF +  WP   VPS+    L+ +
Sbjct: 148 YGELKIRTKKIKSFRNYKVTTLCLTNTNTGTV-LDIKHFAYEDWPQGGVPSDVNNFLDFV 206

Query: 482 LDVNY---RLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
           L V +   + +  ++      ++ + VH SAG+ R   F VID+ + +  +      I +
Sbjct: 207 LAVRHADSKTEVPISSESRVKESPILVHSSAGLDRAPAFCVIDICISKYSESAI---IPL 263

Query: 539 HRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
             TV+ +R QR+  +    QY F Y  VL+F+
Sbjct: 264 LTTVRDLRRQRNNCLSLSTQYIFCYFTVLQFV 295


>UniRef50_A2PZX3 Cluster: GfV-C8-ORF1; n=1; Glypta fumiferanae
           ichnovirus|Rep: GfV-C8-ORF1 - Glypta fumiferanae
           ichnovirus
          Length = 304

 Score =  100 bits (240), Expect = 1e-19
 Identities = 74/268 (27%), Positives = 122/268 (45%), Gaps = 13/268 (4%)

Query: 311 TEEPVKSSKKVHGNGTHK---LPAFEPSVLRPNPNYFNTTIPKSATETENGVPTVHVYNK 367
           T+  +++ +K   N  ++   +P ++ S  R N +  ++T    +T             +
Sbjct: 36  TKPSIEAFEKPENNVKNRRADVPCWDHS--RVNLSNVDSTAANDSTYIHANYVDAFSTER 93

Query: 368 TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI 427
            +IATQ  ++ T+  F  MIWQ +   I++ TK +E  + KC  YW      +  +KYT+
Sbjct: 94  KFIATQAPMAQTVDDFLDMIWQNNCGNIVVLTKMVENNEEKCYPYWSTDMGDKKSEKYTV 153

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPS--EPG--RVLNILLD 483
                    DYT     +  +        I  +H+T W ++ VP+  EP   +   ++  
Sbjct: 154 TTIEIEEIDDYTKYTLQLENRKVAKDFPLISLYHYTHWSENGVPADGEPTVYQFAGLVTA 213

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
           +N    +        A  +V VH SAG GRTGTF  I+  +DQ  +      +D+ R VQ
Sbjct: 214 INIEYDEYCYCGGKFAGPIV-VHGSAGAGRTGTFCAINYCVDQYLRTK---NVDVLRAVQ 269

Query: 544 MVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
            +R  R   V N  QYKFI+  +  FIE
Sbjct: 270 RMRSMRHSSVMNADQYKFIFCVLKSFIE 297



 Score = 39.1 bits (87), Expect = 0.33
 Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 11/73 (15%)

Query: 205 EFET-LQMMENLQLFDRMEGS----------KPENIRKNRYKNIIPFDHTRVILKDIPPD 253
           +++T +Q   NL L DR+ G           KPEN  KNR  ++  +DH+RV L ++   
Sbjct: 14  QYQTAIQDETNLFLLDRVAGGSTKPSIEAFEKPENNVKNRRADVPCWDHSRVNLSNVDST 73

Query: 254 GPPGSDYINANYI 266
               S YI+ANY+
Sbjct: 74  AANDSTYIHANYV 86


>UniRef50_Q966M2 Cluster: Putative uncharacterized protein; n=6;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 346

 Score =  100 bits (240), Expect = 1e-19
 Identities = 68/233 (29%), Positives = 110/233 (47%), Gaps = 28/233 (12%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLN--------- 417
           K +I TQ  L  T   FW M +Q+ V  I M    +E+G  KC  Y+P            
Sbjct: 120 KRFICTQAPLEKTCADFWYMCYQDKVEYIFMLCNLLEKGARKCFEYFPSKKGDVMDFEEG 179

Query: 418 --KTEVVKKYTILNEFESSTP-DYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEP 474
             K  V  + ++   F S    + T    ++    E T K T  H+H+  WPD  VP+  
Sbjct: 180 GQKISVKCESSVTYSFRSDAKANVTATEIVIEGPGEKTRKTT--HYHWNDWPDRGVPAAD 237

Query: 475 GRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDC 534
             VL +L +              P++  + VHCSAGIGRTG+ ++++ I+DQ+   G   
Sbjct: 238 MAVLELLENAR------------PSKGPIVVHCSAGIGRTGSVVMLEYIMDQL-LAGQII 284

Query: 535 EIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPEAAQDS 587
           + D  + +  +R+QR+  +Q +AQY F++  +L +   +K     G + A D+
Sbjct: 285 D-DGEKILVKIREQRNNSIQTDAQYLFVHQVILNYFRKKKLMEETGVQEAYDA 336



 Score = 35.9 bits (79), Expect = 3.1
 Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 11/85 (12%)

Query: 183 KQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKP-ENIRKNRYKNIIPFD 241
           KQ+ K  +  +E M   QG   EF  ++   +   F++M+  K  +   KNRYK++   D
Sbjct: 39  KQILKFVQRTLEKMP--QGLRAEFVGMRRFND---FEKMKAFKEAQEAGKNRYKDVGCLD 93

Query: 242 HTRVILKDIPPDGPPGSDYINANYI 266
           + RV L     +GP   +YI+ANY+
Sbjct: 94  NNRVKL-----EGPWPHEYIHANYV 113


>UniRef50_Q9UDA9 Cluster: Protein-tyrosine phosphatase; n=13;
           Euteleostomi|Rep: Protein-tyrosine phosphatase - Homo
           sapiens (Human)
          Length = 122

 Score =  100 bits (240), Expect = 1e-19
 Identities = 49/130 (37%), Positives = 76/130 (58%), Gaps = 8/130 (6%)

Query: 384 WSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRF 443
           W M+W+++V  IIM TK +E+G+ KCE YWP   + +     T+    E   P++T+R F
Sbjct: 1   WRMVWEQNVYAIIMLTKCVEQGRTKCEEYWPS-KQAQDYGDITVAMTSEIVLPEWTIRDF 59

Query: 444 LVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVV 503
            V K  +T+    +  FHFT+WPDH VP       ++L++  Y ++  M  + P ++  +
Sbjct: 60  TV-KNIQTSESHPLRQFHFTSWPDHGVPD----TTDLLINFRYLVRDYMKQSPPESE--I 112

Query: 504 CVHCSAGIGR 513
            VHCSAGIGR
Sbjct: 113 LVHCSAGIGR 122


>UniRef50_A2Q7J2 Cluster: Contig An01c0050, complete genome; n=1;
           Aspergillus niger|Rep: Contig An01c0050, complete genome
           - Aspergillus niger
          Length = 937

 Score =  100 bits (240), Expect = 1e-19
 Identities = 70/210 (33%), Positives = 111/210 (52%), Gaps = 23/210 (10%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQE--DVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVK 423
           +TYIATQ  +   +  FW M++ E  DV +I+M T+  E G+ KC +Y+P  L++  +  
Sbjct: 701 RTYIATQAPIIGYLSHFWHMVFHESKDVAVIVMLTQTFEAGREKCAQYFPLHLDQASMFL 760

Query: 424 KYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
           + T   +  S      +R+  +T   ET +   ++HF F  WP++  P   G     LL+
Sbjct: 761 ESTFDVKSRSE-----IRKLELTIGSETKI---VWHFLFAGWPEYSKPE--GDDCEALLE 810

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRK----EGFDCEID-I 538
           +  RL    +G   P      VHCS+G+GRTGTFI ++ +L ++      +  D E D +
Sbjct: 811 L-IRLSASKSGPQNPR----VVHCSSGVGRTGTFIALEHLLQELESGQLLQLADPEADPV 865

Query: 539 HRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
             TV  +R+QR  MV N  Q++FIY  + E
Sbjct: 866 FDTVNQMREQRMMMVYNVKQFQFIYDVLRE 895


>UniRef50_P32587 Cluster: Tyrosine-protein phosphatase 3; n=1;
           Schizosaccharomyces pombe|Rep: Tyrosine-protein
           phosphatase 3 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 303

 Score =  100 bits (240), Expect = 1e-19
 Identities = 87/275 (31%), Positives = 127/275 (46%), Gaps = 34/275 (12%)

Query: 311 TEEPVKSSKKVHGNGTHKLPAFEPSVLRPNPNYFNTTIPKSATETENGVPTVHVYNKTYI 370
           T  P  S K +  N    +  +E + +R +P +      K A +  N         KT+I
Sbjct: 40  TRLPKLSKKALARNRYSNIVPYENTRVRLDPMW------KEACDYINASIVKIPSGKTFI 93

Query: 371 ATQGCLSTTIYPFWSMIWQEDVR--IIIMTTKEIERGKVKCERYWP-----DLNKTEV-- 421
           ATQG  S +I  FW M+WQ   +  II+M TK  ER ++KC+ YWP      LN  ++  
Sbjct: 94  ATQGPTSNSIDVFWKMVWQSVPKSGIIVMLTKLRERHRLKCDIYWPVELFETLNIGDLSV 153

Query: 422 --VKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLN 479
             VK YT+     +S  +  +R F + K     VK+ I HF++  WPD   P        
Sbjct: 154 ILVKVYTL-----TSLNEVQVREFELNKDG---VKKKILHFYYNGWPDFGAPHTFS---- 201

Query: 480 ILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQI--RKEGFDCEID 537
            LL +   ++ +    D     ++ VHCSAG GRTGTF+ +  IL Q          E+D
Sbjct: 202 -LLSLTRYIKSLSYSPDFETAPII-VHCSAGCGRTGTFMALFEILSQTDDSTSTSKFEVD 259

Query: 538 -IHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIE 571
            I   V  +R QR   VQ+  Q  F+Y    E ++
Sbjct: 260 NIANIVSSLRSQRMQSVQSVDQLVFLYTVSQELLQ 294



 Score = 39.9 bits (89), Expect = 0.19
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 183 KQLQKENEGPIESMAYKQGFWEEFETLQMMENLQLFDRMEGSKPENIRKNRYKNIIPFDH 242
           K++  EN      +  K+  +   E L   E   L  R+     + + +NRY NI+P+++
Sbjct: 4   KEVSTENGVLTPLITIKEKAYMIIEGLNEEEIELLNTRLPKLSKKALARNRYSNIVPYEN 63

Query: 243 TRVILKDIPPDGPPGSDYINANYIRCDSMDSISDSQEFTGN 283
           TRV L    P      DYINA+ ++  S  +   +Q  T N
Sbjct: 64  TRVRL---DPMWKEACDYINASIVKIPSGKTFIATQGPTSN 101


>UniRef50_UPI0000E475CC Cluster: PREDICTED: similar to
           ENSANGP00000001164, partial; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to
           ENSANGP00000001164, partial - Strongylocentrotus
           purpuratus
          Length = 178

 Score =  100 bits (239), Expect = 1e-19
 Identities = 44/85 (51%), Positives = 56/85 (65%)

Query: 365 YNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
           + K YIATQGCL  T+  FW + WQE+ R+I+MTTKE+ERGK KC RYWPD N  +    
Sbjct: 49  HQKRYIATQGCLKDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTGV 108

Query: 425 YTILNEFESSTPDYTLRRFLVTKKD 449
            T+ +  E S  DY LR F ++ KD
Sbjct: 109 ITVTHISEQSMADYDLREFSMSHKD 133



 Score = 43.2 bits (97), Expect = 0.020
 Identities = 60/209 (28%), Positives = 85/209 (40%), Gaps = 32/209 (15%)

Query: 241 DHTRVILKDIPPDGPPGSDYINANYIRCDSMDSISDSQEFTGNGSTENGKDGTPSKAKDK 300
           DH+RVI+ D    G PG DYIN NYI  D   +  +S E    G  EN +    S    K
Sbjct: 1   DHSRVIIND----GLPG-DYINGNYI--DLPKAWKNSIELQQQG--ENVEKIDMSWEHQK 51

Query: 301 SSPVHTSVIVTEEPVKSSKKVHGNGTHKLPAFEPSVLRPNPNYFNTTIPKSATETENGVP 360
                   +  ++ V    +V      ++       +    N      P + T+ + GV 
Sbjct: 52  RYIATQGCL--KDTVPEFWRVAWQENSRVIVMTTKEVERGKNKCCRYWPDANTKKDTGVI 109

Query: 361 TVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTE 420
           TV     T+I+ Q   S   Y         D+R   M+ K+      KC RYWPD N  +
Sbjct: 110 TV-----THISEQ---SMADY---------DLREFSMSHKDFN----KCCRYWPDANTKK 148

Query: 421 VVKKYTILNEFESSTPDYTLRRFLVTKKD 449
                T+ +  E S  DY LR F ++ KD
Sbjct: 149 DTGVITVTHISEQSMADYDLREFSMSHKD 177


>UniRef50_A5DI66 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 767

 Score =  100 bits (239), Expect = 1e-19
 Identities = 68/208 (32%), Positives = 97/208 (46%), Gaps = 10/208 (4%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTI- 427
           YIATQG L++TI  FW         II+  T E E G  KC  +W     T       + 
Sbjct: 545 YIATQGPLNSTIGDFWKCALDNHCSIIVSLTGETENGVDKCSPFWRAGTYTSNSTSIVVS 604

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
           L E      +  LRRF V+  +     +++   H  +WPD    S+   +L ++      
Sbjct: 605 LEEDAQIDENLLLRRFTVSMGNNK--PQSVLQIHLLSWPDMGSISKSEDILTVVF----- 657

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGF-DCEID-IHRTVQMV 545
           L+Q +      +     +HCSAG GRTGT   ID IL  ++  G  + E D ++  V   
Sbjct: 658 LKQFLLDKLKSSDGRAMIHCSAGCGRTGTLCAIDTILSLMKTNGTNEFERDPVYAIVNSF 717

Query: 546 RDQRSGMVQNEAQYKFIYMAVLEFIETE 573
           R+QR  MVQN  QY  IY  +L F++ E
Sbjct: 718 RNQRISMVQNLRQYNSIYDTILLFLKDE 745



 Score = 35.5 bits (78), Expect = 4.1
 Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 3/45 (6%)

Query: 231 KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCDSMDSIS 275
           KNRYK+I  ++H+RV L++         DYINA+YI    +   S
Sbjct: 494 KNRYKDIFVYEHSRVRLQE---QQQQACDYINASYIDPSGLQEFS 535


>UniRef50_Q6C0H6 Cluster: Similar to tr|Q9P664 Neurospora crassa
           Related to protein-tyrosine- phosphatase; n=1; Yarrowia
           lipolytica|Rep: Similar to tr|Q9P664 Neurospora crassa
           Related to protein-tyrosine- phosphatase - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 687

 Score =   99 bits (238), Expect = 2e-19
 Identities = 65/209 (31%), Positives = 101/209 (48%), Gaps = 11/209 (5%)

Query: 367 KTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYT 426
           + YIATQ  L  T   F+ MIW+E V +I+    E E   +KC  YW +        +  
Sbjct: 481 RVYIATQAPLPETFADFFHMIWEEKVPVIVQLAPEFEGAMLKCHNYWGEGTHGPYTVRVI 540

Query: 427 ILNEFESSTPD---YTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
              + +  T D    T+R F V+++    V R +    + AWPD   P+ P  +L ++  
Sbjct: 541 ATRKEDVDTKDNIVATIRTFEVSREG---VVRHVTQIFYDAWPDLGRPANPADLLRLMEL 597

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRK--EGFDCEIDIHRT 541
            +  L+      D      V VHCSAG GRTGTF  ID++ D +++    +  +  +   
Sbjct: 598 KDGILKHAKLPVD---GTKVVVHCSAGCGRTGTFCAIDIVCDILQRGDPQYQHKDVVAEV 654

Query: 542 VQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
           V  +R QR+ MVQ+  QY   Y +VL ++
Sbjct: 655 VAELRTQRTSMVQSLRQYVLCYDSVLAWL 683



 Score = 36.7 bits (81), Expect = 1.8
 Identities = 19/36 (52%), Positives = 23/36 (63%), Gaps = 4/36 (11%)

Query: 231 KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           KNRY NI P++HTRV L         G DYINA++I
Sbjct: 443 KNRYDNIYPYEHTRVKL----ARKTQGCDYINASHI 474


>UniRef50_P27574 Cluster: Tyrosine-protein phosphatase 1; n=1;
           Schizosaccharomyces pombe|Rep: Tyrosine-protein
           phosphatase 1 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 550

 Score =   99 bits (238), Expect = 2e-19
 Identities = 65/208 (31%), Positives = 100/208 (48%), Gaps = 24/208 (11%)

Query: 369 YIATQGCLSTTIYPFWSMIWQ--EDVRIIIMTTKEIERGKVKCERYWPD--LNKTEVVKK 424
           YIA QG +S +I  FW M+W   E++  I+M     E G+  C  YWP   +   +V   
Sbjct: 337 YIACQGSISRSISDFWHMVWDNVENIGTIVMLGSLFEAGREMCTAYWPSNGIGDKQVYGD 396

Query: 425 YTI--LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILL 482
           Y +  ++E       + LR+F +   +  +VK+ ++H+ +  W D   P     ++  L 
Sbjct: 397 YCVKQISEENVDNSRFILRKFEIQNANFPSVKK-VHHYQYPNWSDCNSPENVKSMVEFLK 455

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMIL--DQIRKEGF-----DCE 535
            VN          +        VHCSAG+GRTGTFIV+D IL   + +  GF     D  
Sbjct: 456 YVN----------NSHGSGNTIVHCSAGVGRTGTFIVLDTILRFPESKLSGFNPSVADSS 505

Query: 536 IDIHRTVQMVRDQRSGMVQNEAQYKFIY 563
             + + V  +R QR  MVQ   Q+K++Y
Sbjct: 506 DVVFQLVDHIRKQRMKMVQTFTQFKYVY 533



 Score = 38.7 bits (86), Expect = 0.44
 Identities = 19/46 (41%), Positives = 31/46 (67%), Gaps = 3/46 (6%)

Query: 230 RKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIRCDSMDSIS 275
           +KNRY +I+P++ TRV LK      P   DYINA++I+ ++ + I+
Sbjct: 297 KKNRYTDIVPYNCTRVHLK---RTSPSELDYINASFIKTETSNYIA 339


>UniRef50_A2QDC9 Cluster: Contig An02c0190, complete genome; n=5;
           Trichocomaceae|Rep: Contig An02c0190, complete genome -
           Aspergillus niger
          Length = 555

 Score = 99.5 bits (237), Expect = 2e-19
 Identities = 80/261 (30%), Positives = 122/261 (46%), Gaps = 36/261 (13%)

Query: 361 TVHVYNKTYIATQGCLSTTIYPFWSMIWQE--DVRIIIMTTKEIERGKVKCERYWP-DLN 417
           +V    + YIATQG     +  FW M++ E  DV +I+M T+  E G+ KC +Y+P D  
Sbjct: 262 SVSQQERRYIATQGPKPDHLSHFWHMVFHESDDVGVIVMLTQTFEAGREKCAQYFPLDRE 321

Query: 418 KTEV----VKKYTILNEFESSTPDYTLRRF---LVTKKDET-------------TVKRTI 457
              +    V++   +N+      D  L  +   L T+ D T             T  + +
Sbjct: 322 NPTMPLRRVEQDPFVNDHHHQQADEDLLGYVTLLETQWDPTSRSEIRKLRLTLGTESKIV 381

Query: 458 YHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTF 517
           +HF F  W D+  P    R      D   +L ++      PA   + VHCSAG+GRTGTF
Sbjct: 382 WHFLFAGWADYSKPEGEDR------DALLQLIKLSGSKCTPANPRI-VHCSAGVGRTGTF 434

Query: 518 IVIDMILDQIRK----EGFDCEID-IHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIET 572
           I +D +L ++      E  D +ID +  TV  +R+QR  MV NE Q +FIY  + E  + 
Sbjct: 435 IALDHLLQELESGQLLEATDPDIDPVFETVNQMREQRMMMVYNEMQLQFIYEVLREQTDL 494

Query: 573 EKQRVGLGPEAAQDSPRARSM 593
           +  +  L P   +   R+  M
Sbjct: 495 KLGKTAL-PSGRKSDERSTKM 514


>UniRef50_Q5W3K6 Cluster: Putative tyrosine phosphatase protein;
           n=3; Toxoneuron nigriceps polydnavirus|Rep: Putative
           tyrosine phosphatase protein - Toxoneuron nigriceps
           polydnavirus
          Length = 297

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 66/211 (31%), Positives = 105/211 (49%), Gaps = 16/211 (7%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYW-PDLNKTEVVKKYTI 427
           +IATQ  L TT+  FW M+W E+ ++I+M  K +E    K   YW PD+     + K+ I
Sbjct: 96  FIATQAPLRTTVEDFWRMVWSENTKMIVMLMK-LE--DPKYFPYWSPDIGNHITIGKFKI 152

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
            +   S    Y +   L+    E T  R I+H+ +  WP++ VP+     LN L  ++ +
Sbjct: 153 -STIVSYKASYYVHTVLLIINQEITELRLIHHYCYQEWPNYSVPTNFECFLNFLNVISEK 211

Query: 488 LQQI---MTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQM 544
            + +    T  DP     + VHCSAG+GRTGTF  I   +  I + G    +++   V+ 
Sbjct: 212 RKLLCPKTTSCDP-----IIVHCSAGVGRTGTFCAIMNAIKSIEQTG---TVNLFEIVKK 263

Query: 545 VRDQRSGMVQNEAQYKFIYMAVLEFIETEKQ 575
           VR  R   V  + QY F Y  ++ ++ +  Q
Sbjct: 264 VRINRPLSVVVQNQYLFCYQILVHYVTSMPQ 294


>UniRef50_Q0MW10 Cluster: Protein tyrosine phosphatase 1; n=4;
           Bracovirus|Rep: Protein tyrosine phosphatase 1 - Cotesia
           glomerata bracovirus
          Length = 299

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 60/210 (28%), Positives = 97/210 (46%), Gaps = 6/210 (2%)

Query: 369 YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK-KYTI 427
           ++ TQ  L  T   FW MI+   VR+I+M T+ +E G+  C  YW    + ++V  K+TI
Sbjct: 95  FLCTQAPLQETTQDFWKMIFTNQVRVIVMLTRLVEDGREACYPYWSPKKRGKMVHGKFTI 154

Query: 428 LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
                     + +    VT  ++T     I HF +  WP + +P +P   L+ +L V   
Sbjct: 155 KTLKIKFFRYHVVTSLRVT--NDTGASLDIKHFAYNDWPSYSLPRDPSNFLDFVLSVRKA 212

Query: 488 LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRD 547
                 G+D      + VHCSAG+ RTG F  ID+ L Q  +      I +   ++ +R 
Sbjct: 213 QLMADLGSDGENVPPMVVHCSAGLNRTGAFCAIDISLSQYDER---ATISLSSVLRNLRK 269

Query: 548 QRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
           QR   +     Y F Y+ V+ + +    R+
Sbjct: 270 QRHNCLCLPEHYVFCYLIVVIYAKLVADRL 299



 Score = 36.3 bits (80), Expect = 2.3
 Identities = 21/42 (50%), Positives = 24/42 (57%), Gaps = 4/42 (9%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           K EN  K RY N   FD  RVIL    P    GSD+INAN++
Sbjct: 49  KLENWSKCRYWNTFMFDRNRVIL----PTEDGGSDFINANHV 86


>UniRef50_Q61XF0 Cluster: Putative uncharacterized protein CBG04012;
           n=2; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG04012 - Caenorhabditis
           briggsae
          Length = 538

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 64/216 (29%), Positives = 103/216 (47%), Gaps = 22/216 (10%)

Query: 366 NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-------DLNK 418
           N+ +I  Q  L+ T+  FW MI    + +I+M  + +E GK K   Y+P        + K
Sbjct: 315 NRRFICAQAPLAGTVEEFWKMIIFSGLELIVMLCEFVETGKQKSAVYFPAKVGASMKIGK 374

Query: 419 TEVVKKYTILNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVL 478
              V K +            T+    +TKKD+     T+ H H+  WPDH VP       
Sbjct: 375 LCTVTKISNFQLVLQLDKTLTMSTLRITKKDKQDATLTVKHIHWHNWPDHGVPD------ 428

Query: 479 NILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDI 538
           N +  +  RL  +   +  P    + VHCSAG+GRTGT ++I +IL+      F     +
Sbjct: 429 NFISPL--RLLNLYRASPKP----IIVHCSAGVGRTGTLVLIFIILESFSLPDF---AGV 479

Query: 539 HRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEK 574
            R +  +R++R   +Q E QY +++  VLE++  +K
Sbjct: 480 PRLLAKLREERFKSIQTEMQYLYVHRCVLEYLVYKK 515


>UniRef50_Q0U823 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 552

 Score = 99.1 bits (236), Expect = 3e-19
 Identities = 73/218 (33%), Positives = 106/218 (48%), Gaps = 23/218 (10%)

Query: 369 YIATQGCLSTTIYPFWSMIWQE--DVRIIIMTTKEIERGKVKCERYWPD--------LNK 418
           YIATQG ++ +    W MIW+E  D  +I+M T+  E G+ KC  Y+P         +N+
Sbjct: 170 YIATQGPIADSWSHIWRMIWKENQDPAVIVMLTQTHETGREKCYPYYPQSPSNPDMRINE 229

Query: 419 TEVVKKYTILNEFESSTPDYTLRRFLVTKKDETT----VKRTIYHFHFTAWPDHRVPSEP 474
            +  +   I N   +S       R  V + D TT      R I+H  F  WPD   P   
Sbjct: 230 HDEFEDGLIHNLHLASLHQDEEARTQVREIDMTTDDSDEMRKIWHLLFAGWPDFSAPEGA 289

Query: 475 GRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDC 534
            R   + L    R +     T+P       VHCSAGIGR+GTFI ++ +L ++ +   D 
Sbjct: 290 DRAALLRLIEISREKGGDLATNPRI-----VHCSAGIGRSGTFIALEYLLQELAEGSLDA 344

Query: 535 EID----IHRTVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
             D    I   +  +RDQR+GMVQ + Q+ F+Y A+ E
Sbjct: 345 VPDTDDPIVSVITQLRDQRAGMVQAKLQFLFLYDALRE 382


>UniRef50_Q9NL00 Cluster: HgPTPR5b protein; n=1; Eptatretus
           burgeri|Rep: HgPTPR5b protein - Eptatretus burgeri
           (Inshore hagfish)
          Length = 253

 Score = 98.7 bits (235), Expect = 4e-19
 Identities = 68/208 (32%), Positives = 106/208 (50%), Gaps = 30/208 (14%)

Query: 387 IWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLV- 445
           +W+ DVRIIIM T  +E+G+ KC+ YWP +   E      +      +   YT+RRF + 
Sbjct: 1   VWEHDVRIIIMITNLVEKGRRKCDPYWP-MEGGEEYGTVVVTLRATRTLACYTVRRFTLR 59

Query: 446 ----TKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNIL-------------LDVNYRL 488
                + ++  V+RT+  F +T+WPD   P     +L  +               V   L
Sbjct: 60  LTKPRRANQRGVERTVLQFQYTSWPDMGTPEHALPLLAFVRTTVQAAAQAAAQASVQATL 119

Query: 489 Q-----QIMTGTDPPAQ---AVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHR 540
           Q     Q  +   P  +     V VHCSAG+GRTGT+IV+  +L Q++++G    I I  
Sbjct: 120 QASSKSQTRSKKKPRGRVGPGPVVVHCSAGVGRTGTYIVLASMLQQMKEKG---TIGIKG 176

Query: 541 TVQMVRDQRSGMVQNEAQYKFIYMAVLE 568
            ++ +R QR+ +VQ E QY F++ A+LE
Sbjct: 177 FLKHIRTQRNFLVQTEEQYIFLHEALLE 204


>UniRef50_Q4RQG0 Cluster: Chromosome 17 SCAF15006, whole genome
            shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome 17 SCAF15006, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 1865

 Score = 98.7 bits (235), Expect = 4e-19
 Identities = 55/160 (34%), Positives = 83/160 (51%), Gaps = 12/160 (7%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWP-DLNKTEVVKKYTI 427
            YI+ QG L +T+  FW MIW+    +I M T+E+ERG++KC +YWP  L  +     Y +
Sbjct: 1697 YISCQGPLPSTVTAFWQMIWENKSDVIAMMTQEVERGRIKCHKYWPARLGASLDAGGYQL 1756

Query: 428  LNEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYR 487
              E +     + ++   + +K E+     ++H  FT WPDH VP    +++  +     R
Sbjct: 1757 HLENQQFLEYFHIKVIRMVEK-ESGETHLVHHLKFTHWPDHGVPHSSDQLVRFI-----R 1810

Query: 488  LQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQI 527
              + +    P     V VHCSAGIGR G  I  D+IL  I
Sbjct: 1811 YMRAVHSRGP-----VTVHCSAGIGRAGVLICTDVILGLI 1845



 Score = 49.2 bits (112), Expect = 3e-04
 Identities = 27/57 (47%), Positives = 36/57 (63%), Gaps = 8/57 (14%)

Query: 212  MENLQLFDR-MEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
            +E+LQ  D  + G  PEN  KNRY++I+P+D TRV + D         DYINA+YIR
Sbjct: 1638 LEHLQPSDNCLVGKAPENRDKNRYRDILPYDQTRVAIGD-------NRDYINASYIR 1687


>UniRef50_Q5K8S3 Cluster: Protein-tyrosine-phosphatase, putative; n=1;
            Filobasidiella neoformans|Rep:
            Protein-tyrosine-phosphatase, putative - Cryptococcus
            neoformans (Filobasidiella neoformans)
          Length = 1409

 Score = 98.3 bits (234), Expect = 5e-19
 Identities = 66/194 (34%), Positives = 101/194 (52%), Gaps = 29/194 (14%)

Query: 366  NKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLN----KTEV 421
            ++ YIATQG L  T   FW+++W+++VRII+M TK+ E G +KC  YW +      K ++
Sbjct: 866  SRRYIATQGPLDATYRDFWTLVWEQNVRIIVMITKQFEGGLIKCGNYWCEERYGHIKLQL 925

Query: 422  VKKY----TILNEFES--------STP---------DYTLRR-FLVTKKDE-TTVKRTIY 458
            + +     T L    S        +TP         D  ++R FL+++ D+     R I 
Sbjct: 926  ISQSGGEDTALPAANSGFDFGTAGATPKSSKFPQESDSNIKRVFLISRDDKPDQPPRKIV 985

Query: 459  HFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIM-TGTDPPA-QAVVCVHCSAGIGRTGT 516
                  WPD  VP  P  +L ++ +VN    +    G    A +  V VHCSAG+GRTG+
Sbjct: 986  QLQCIGWPDFDVPETPDTLLKLIQEVNDAAHEAKPEGCYRKADEPPVLVHCSAGVGRTGS 1045

Query: 517  FIVIDMILDQIRKE 530
            FIV+D ILD + ++
Sbjct: 1046 FIVVDAILDGLHRD 1059



 Score = 44.8 bits (101), Expect = 0.007
 Identities = 26/55 (47%), Positives = 35/55 (63%), Gaps = 3/55 (5%)

Query: 213 ENLQLFDRMEGSKPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYIR 267
           E+++ F     +  E   KNRYKNI P+D +RV L D PPD    SDYINA++I+
Sbjct: 810 EDIEYFPFSITAGVERGTKNRYKNIWPYDFSRVRL-DSPPD--QDSDYINASFIQ 861


>UniRef50_UPI000065EB91 Cluster: Homolog of Homo sapiens "Splice
            Isoform Long of Receptor-type tyrosine-protein
            phosphatase zeta precursor; n=1; Takifugu rubripes|Rep:
            Homolog of Homo sapiens "Splice Isoform Long of
            Receptor-type tyrosine-protein phosphatase zeta precursor
            - Takifugu rubripes
          Length = 1506

 Score = 97.5 bits (232), Expect = 9e-19
 Identities = 74/221 (33%), Positives = 112/221 (50%), Gaps = 33/221 (14%)

Query: 369  YIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKKYTIL 428
            YIA QG L ++   FW +IW+++V +I+M TK +E G     RYWP  +  +V   Y + 
Sbjct: 1019 YIAAQGPLKSSTDDFWRIIWEQNVGVIVMITKLVENG-----RYWP-TDMPQVYGSYLVT 1072

Query: 429  NEFESSTPDYTLR----RFLVTKK---------DETTVKRTIYHFHFTAWPDHRVPSEPG 475
             +       YT R    R + TKK            +++RTI  + +T WPD  VP    
Sbjct: 1073 LKSSRVLAHYTQRTLTLRNIHTKKVLPLLEGCQRGRSIERTITQYQYTQWPDIGVPDFAL 1132

Query: 476  RVLNILLDVNYRLQQIMTGTDPPAQAVVCVHC------SAGIGRTGTFIVIDMILDQIRK 529
             +L+ +     R  +  T    P   + C  C      SAG+GRTGT+IV+D +L QIR 
Sbjct: 1133 PLLSFI----RRSSKARTDDMGPV-VIHCRSCSLFVFHSAGVGRTGTYIVLDSMLKQIRD 1187

Query: 530  EGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFI 570
            +     ++I   ++ +R QR+ +VQ E QY FI+ A+ E I
Sbjct: 1188 QN---AVNIMAFLKHIRKQRNYLVQTEEQYVFIHDALAEAI 1225



 Score = 42.7 bits (96), Expect = 0.027
 Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 23/200 (11%)

Query: 361  TVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTT----KEIERGKVKCERYWPDL 416
            T + +++ +I TQ  L  T+  FW M+W  + RII+        E E     C   WP  
Sbjct: 1316 TGYRHSREFIITQNPLPGTMKDFWRMVWDHNARIIVSLQAAWGSEAEEEVGLC-ALWPQK 1374

Query: 417  NKTEVVKKYTILNEFES----STPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPS 472
             +    + +T++ + E     S+ D  +    V +  +      +  +   +WP+     
Sbjct: 1375 GQKICYELFTVMQKNEDRICLSSEDVLVIHNYVLESTKDDFVLEVKQYCAPSWPN----- 1429

Query: 473  EPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGF 532
             P R +N   +V   + +     D P      VH   G     TF V+  +  Q+  EG 
Sbjct: 1430 -PDRPINNTFEV-VAMVKNQGAIDGP----TVVHDLVGGVTAATFCVLTFLTQQLEAEG- 1482

Query: 533  DCEIDIHRTVQMVRDQRSGM 552
               +D+ +  +M    R G+
Sbjct: 1483 --SVDVFQVAKMTNLMRPGV 1500


>UniRef50_P91345 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 518

 Score = 97.5 bits (232), Expect = 9e-19
 Identities = 67/207 (32%), Positives = 101/207 (48%), Gaps = 18/207 (8%)

Query: 368 TYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVK--KY 425
           TYI TQG L  T+  FW MI+QE +  ++M     E G  KC  Y+P+    EVVK  KY
Sbjct: 245 TYITTQGPLPETLSDFWHMIYQEKIAYVLMLCTLFEGGVEKCALYYPE-KLGEVVKFGKY 303

Query: 426 TI-LNEFESSTPDYTLRRFLVTKKDETTVKRTIY--HFHFTAWPDHRVPSEPGRVLNILL 482
            I L E +      T+   L     E      +Y  H     WPD   P +   ++ +  
Sbjct: 304 EITLTECKEEAIAGTILNSLTVINTEDATSEPLYMNHVQVPWWPDQLAPEDARPMIEL-- 361

Query: 483 DVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTV 542
              Y+  + +     P +  +CVHCSAG+GRT TF+ ID    +I +      +DI R +
Sbjct: 362 ---YKWVKKVN----PKEKPICVHCSAGVGRTATFVGIDYATIRIMENPNIEMLDIVREM 414

Query: 543 QMVRDQRSGMVQNEAQYKFIYMAVLEF 569
           + +R Q    VQ+  Q+ F+Y+ ++E+
Sbjct: 415 RAMRFQ---AVQSHMQFLFLYVVLMEY 438


>UniRef50_Q4EW66 Cluster: Protein tyrosine phosphatase A; n=1;
           Entamoeba histolytica|Rep: Protein tyrosine phosphatase
           A - Entamoeba histolytica
          Length = 350

 Score = 97.1 bits (231), Expect = 1e-18
 Identities = 54/169 (31%), Positives = 95/169 (56%), Gaps = 9/169 (5%)

Query: 363 HVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVV 422
           +V+   YI+ Q  L+TTI  F++M+W+++  II+M TK  E+ ++K  RY+P+    +  
Sbjct: 67  YVFGGRYISCQAPLTTTIEDFYNMVWEQETPIIVMLTKYEEKNRIKATRYFPENGIEQKY 126

Query: 423 KKY-----TIL-NEFESSTPDYTLRRFLVTKKDETTVKRTIYHFHFTAWPDHRVPSEPGR 476
            K+     TIL N+ ++     T  R ++ +      KR+I H H+T WPD  VPS   +
Sbjct: 127 GKFNVKVGTILYNDLQTIKRMETQVREIIIENQIEKSKRSIIHIHYTGWPDFGVPSNIKQ 186

Query: 477 VLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILD 525
           + ++L  ++   +  + G       +  +HCSAG+GR+GTFI++  I +
Sbjct: 187 ITDMLF-ISLVCRGKIKGIKLNGPPI--IHCSAGLGRSGTFIILFRIYE 232



 Score = 35.1 bits (77), Expect = 5.4
 Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 8/42 (19%)

Query: 225 KPENIRKNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           K  N+ KNRYKN++  + T V LK          DYINANY+
Sbjct: 35  KASNLTKNRYKNVLANNRTIVPLK--------SGDYINANYV 68


>UniRef50_Q7YZG5 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 361

 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 74/239 (30%), Positives = 109/239 (45%), Gaps = 29/239 (12%)

Query: 347 TIPKSATET---ENGVPTVHVYNKTYIATQGCLSTTIYPFWSMIWQEDVRIIIMTTKEIE 403
           TI KS  E     N V T ++ N T+I TQG L  TI  FW MI+QE    I+M  K +E
Sbjct: 115 TIDKSRYEDYIHANYVKTNYLRN-TFICTQGPLQHTIIDFWRMIFQERAESILMLCKTME 173

Query: 404 RGKVKCERYWPDLNKTEVVKKYTILNEFESSTPDYTLRRFLVT---------KKDETTVK 454
            G+ KC  YWP L  TE      + N  ESS  ++ +    VT         ++     +
Sbjct: 174 EGRPKCVGYWPSLGVTETYGCIRVTNMGESS-DEFEICNLAVTFVPDNVPVDEQPANLKE 232

Query: 455 RTIYHFHFTAWPDHRVPSEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRT 514
             +    +  WPD  VP E    +   L     L Q+  G          VHCSAGIGRT
Sbjct: 233 LRVNLIKWPNWPDRGVPDEKCHTVPQRL-----LAQVRHGP-------CVVHCSAGIGRT 280

Query: 515 GTFIVIDMILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETE 573
           G  + ++   +++ +     ++D    +  +R QR+  +Q E QY +I+  ++ F   E
Sbjct: 281 GCVVALEFAYNKLDR---GLKVDFEEIITELRKQRAQCIQTEIQYLYIHRVMIAFARGE 336


>UniRef50_Q6BEU3 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 753

 Score = 95.9 bits (228), Expect = 3e-18
 Identities = 58/214 (27%), Positives = 107/214 (50%), Gaps = 14/214 (6%)

Query: 366 NKTYIATQGCLSTTIYP-FWSMIWQEDVRIIIMTTKEIERGKVKCERYWPDLNKTEVVKK 424
           +K Y+ TQ   +  +   FW M+W+     I+M TK  +  +V C +YWP L K +  + 
Sbjct: 181 DKAYVVTQAVRTKPMNAEFWRMVWELGSNCIVMLTKVFDFMRVMCLQYWP-LTKFQFREI 239

Query: 425 YTILNEFESSTPDYTLRRFLVTKKDETTVK-RTIYHFHFTAWPDHRVPSEPGRVLNILLD 483
                E ++ +  + +R F +T+    +++ R + HFHFT W     P      ++  ++
Sbjct: 240 EVETTEVKTYS-HFVIRTFKLTRTTPESIETRIVKHFHFTEWELDSFP-----YISAFIE 293

Query: 484 VNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDMILDQIRKEGFDCEIDIHRTVQ 543
           +  R++Q M     P +A + VHCS G GR+G F+ +D  L+ ++K G   ++D     +
Sbjct: 294 LRRRVRQFMEKN--PVEAPMVVHCSNGAGRSGAFLALDANLELMKKTG---QLDFFEYAK 348

Query: 544 MVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRV 577
            + + R  ++ +  QY FIY  + E +    Q +
Sbjct: 349 TLVNSRPHLIDSVEQYMFIYEVLSEAVMCNVQPI 382



 Score = 42.7 bits (96), Expect = 0.027
 Identities = 32/134 (23%), Positives = 63/134 (47%), Gaps = 9/134 (6%)

Query: 465 WP-DHRVP-SEPGRVLNILLDVNYRLQQIMTGTDPPAQAVVCVHCSAGIGRTGTFIVIDM 522
           WP +++VP S  G +  I +  ++R +      D P      V    G+ R G +I  ++
Sbjct: 588 WPIENKVPLSTTGLIDVIKMARSWRKR----APDRPETKPTIVMSHNGVSRVGVYIGANI 643

Query: 523 ILDQIRKEGFDCEIDIHRTVQMVRDQRSGMVQNEAQYKFIYMAVLEFIETEKQRVGLGPE 582
            +DQ+     D E+D+   V+M+R  R  ++  + +YK++Y  +L +  T         E
Sbjct: 644 CIDQM---DIDHEVDVFHAVKMMRINRPQLIDMKDEYKYLYDVMLHWYMTNPDYRIYDKE 700

Query: 583 AAQDSPRARSMPVP 596
            ++D+   ++   P
Sbjct: 701 DSEDTDSQKTSRPP 714



 Score = 37.1 bits (82), Expect = 1.3
 Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 2/36 (5%)

Query: 231 KNRYKNIIPFDHTRVILKDIPPDGPPGSDYINANYI 266
           +N Y + +P+D+ RVIL  I  DG   S YINA+Y+
Sbjct: 142 RNPYPDTLPYDYNRVILPRI--DGDENSHYINASYV 175


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.135    0.406 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 715,227,878
Number of Sequences: 1657284
Number of extensions: 32026685
Number of successful extensions: 79229
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 550
Number of HSP's successfully gapped in prelim test: 302
Number of HSP's that attempted gapping in prelim test: 76184
Number of HSP's gapped (non-prelim): 1847
length of query: 598
length of database: 575,637,011
effective HSP length: 105
effective length of query: 493
effective length of database: 401,622,191
effective search space: 197999740163
effective search space used: 197999740163
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 75 (34.3 bits)

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