BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA001098-TA|BGIBMGA001098-PA|IPR000917|Sulfatase (455 letters) Database: human 224,733 sequences; 73,234,838 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BC129996-1|AAI29997.1| 569|Homo sapiens arylsulfatase family, m... 265 2e-70 BC129995-1|AAI29996.1| 569|Homo sapiens arylsulfatase family, m... 265 2e-70 AY875937-1|AAW66665.1| 569|Homo sapiens arylsulfatase I protein. 265 2e-70 M32373-1|AAA51779.1| 533|Homo sapiens ARSB protein. 260 5e-69 X72735-1|CAA51272.1| 533|Homo sapiens arylsulfatase protein. 260 1e-68 J05225-1|AAA51784.1| 533|Homo sapiens ARSB protein. 260 1e-68 BC029051-1|AAH29051.1| 413|Homo sapiens arylsulfatase B protein. 260 1e-68 BC132881-1|AAI32882.1| 599|Homo sapiens ARSJ protein protein. 259 1e-68 BC132879-1|AAI32880.1| 599|Homo sapiens ARSJ protein protein. 259 1e-68 BC089445-1|AAH89445.1| 578|Homo sapiens Unknown (protein for IM... 259 1e-68 AY875938-1|AAW66666.1| 599|Homo sapiens arylsulfatase J protein. 259 1e-68 AM049401-1|CAJ18095.1| 596|Homo sapiens arylsulfatase J protein. 259 1e-68 AY358647-1|AAQ89010.1| 515|Homo sapiens APRG372 protein. 252 1e-66 U06088-1|AAC51350.1| 522|Homo sapiens N-acetylgalactosamine 6-s... 107 8e-23 D17629-1|BAA04535.1| 522|Homo sapiens N-acetylgalactosamine 6-s... 107 8e-23 BC056151-1|AAH56151.1| 522|Homo sapiens galactosamine (N-acetyl... 107 8e-23 BC050684-1|AAH50684.2| 522|Homo sapiens galactosamine (N-acetyl... 107 8e-23 AK131096-1|BAC85146.1| 456|Homo sapiens FLJ00319 protein protein. 107 8e-23 AY129021-1|AAM98764.1| 337|Homo sapiens unknown protein. 73 3e-12 X52151-1|CAA36399.1| 507|Homo sapiens arylsulfatase A protein. 66 2e-10 X52150-1|CAA36398.1| 507|Homo sapiens arylsulphatase a protein. 66 2e-10 U62317-1|AAB03341.1| 509|Homo sapiens arylsulfatase A protein. 66 2e-10 CR456383-1|CAG30269.1| 509|Homo sapiens ARSA protein. 66 2e-10 AY271820-1|AAP03431.1| 507|Homo sapiens arylsulfatase A protein. 66 2e-10 BC014210-1|AAH14210.2| 507|Homo sapiens arylsulfatase A protein. 65 4e-10 AY875940-1|AAW66668.1| 562|Homo sapiens arylsulfatase H protein. 62 4e-09 BC012375-1|AAH12375.1| 525|Homo sapiens arylsulfatase G protein. 60 2e-08 AY358380-1|AAQ88746.1| 525|Homo sapiens GWLF839 protein. 60 2e-08 AB023218-1|BAA76845.2| 551|Homo sapiens KIAA1001 protein protein. 60 2e-08 X97868-1|CAA66462.1| 591|Homo sapiens arylsulphatase protein. 58 8e-08 BC022389-1|AAH22389.1| 590|Homo sapiens ARSF protein protein. 58 8e-08 X83573-1|CAA58556.1| 589|Homo sapiens ARSE protein. 52 6e-06 BC130438-1|AAI30439.1| 589|Homo sapiens arylsulfatase E (chondr... 52 6e-06 AK223199-1|BAD96919.1| 589|Homo sapiens arylsulfatase E precurs... 52 6e-06 X83572-1|CAA58555.1| 593|Homo sapiens ARSD protein. 50 1e-05 BC020229-1|AAH20229.1| 593|Homo sapiens ARSD protein protein. 50 1e-05 AK223183-1|BAD96903.1| 589|Homo sapiens arylsulfatase E precurs... 49 3e-05 M16505-1|AAA60596.1| 583|Homo sapiens STS protein. 47 2e-04 J04964-1|AAA60597.1| 583|Homo sapiens STS protein. 47 2e-04 BC075030-1|AAH75030.1| 583|Homo sapiens steroid sulfatase (micr... 47 2e-04 AF160499-1|AAF22253.1| 382|Homo sapiens arylsulfatase D beta pr... 41 0.008 BC007825-1|AAH07825.2| 238|Homo sapiens GALNS protein protein. 41 0.010 AY101175-1|AAM76860.1| 871|Homo sapiens extracellular sulfatase... 41 0.010 AF545571-1|AAO33315.1| 871|Homo sapiens sulfatase SULF1 precurs... 41 0.010 AB029000-1|BAA83029.1| 818|Homo sapiens KIAA1077 protein protein. 41 0.010 Z12173-1|CAA78164.1| 552|Homo sapiens N-acetylglucosamine-6-sul... 38 0.097 BX537363-1|CAD97608.1| 496|Homo sapiens hypothetical protein pr... 38 0.097 BC012482-1|AAH12482.1| 552|Homo sapiens glucosamine (N-acetyl)-... 38 0.097 AK223484-1|BAD97204.1| 552|Homo sapiens glucosamine (N-acetyl)-... 38 0.097 U60111-1|AAB17952.1| 502|Homo sapiens N-sulphoglucosamine sulph... 37 0.17 U30894-1|AAA86530.1| 502|Homo sapiens N-sulphoglucosamine sulph... 37 0.17 BC047318-1|AAH47318.1| 502|Homo sapiens N-sulfoglucosamine sulf... 37 0.17 BC130329-1|AAI30330.1| 536|Homo sapiens arylsulfatase family, m... 36 0.39 BC036047-1|AAH36047.1| 542|Homo sapiens ARSK protein protein. 36 0.39 AY875939-1|AAW66667.1| 536|Homo sapiens arylsulfatase K protein. 36 0.39 AY358596-1|AAQ88959.1| 536|Homo sapiens Bone Rel Sulphatase pro... 36 0.39 AL832711-1|CAD38634.1| 483|Homo sapiens hypothetical protein pr... 36 0.39 AK222890-1|BAD96610.1| 502|Homo sapiens N-sulfoglucosamine sulf... 34 0.90 M58342-1|AAA63197.1| 550|Homo sapiens iduronate 2-sulfatase pro... 34 1.2 L40586-1|AAA92014.1| 343|Homo sapiens iduronate-2-sulphatase pr... 34 1.2 L13329-1|AAA16877.1| 550|Homo sapiens iduronate-2-sulfatase pro... 34 1.2 L04586-1|AAA59192.1| 398|Homo sapiens iduronate 2-sulfatase pro... 34 1.2 BC018054-1|AAH18054.1| 453|Homo sapiens ectonucleotide pyrophos... 34 1.2 AL035701-3|CAB56567.1| 453|Homo sapiens ectonucleotide pyrophos... 34 1.2 AF011889-1|AAC77828.1| 550|Homo sapiens iduronate 2-sulfatase p... 34 1.2 AB020686-1|BAA74902.2| 461|Homo sapiens KIAA0879 protein protein. 34 1.2 Y08110-1|CAA69325.1| 2214|Homo sapiens mosaic protein LR11 protein. 33 1.6 U60975-1|AAC50891.2| 2214|Homo sapiens gp250 precursor protein. 33 1.6 Y10183-1|CAA71256.1| 582|Homo sapiens MEMD protein protein. 32 3.6 L38608-1|AAB59499.1| 583|Homo sapiens alcam protein. 32 3.6 DQ486140-1|ABF48406.1| 583|Homo sapiens activated leukocyte cel... 32 3.6 DQ486139-1|ABF48405.1| 570|Homo sapiens activated leukocyte cel... 32 3.6 >BC129996-1|AAI29997.1| 569|Homo sapiens arylsulfatase family, member I protein. Length = 569 Score = 265 bits (650), Expect = 2e-70 Identities = 129/298 (43%), Positives = 185/298 (62%), Gaps = 10/298 (3%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I +P LPL++ LPQ L++ GY TH+VGKWHLG Y+KE LP RGFD+ +G Sbjct: 111 LQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGS 170 Query: 61 WTGRIDMYDHTTME-QGSWGTDFRRGFEVAHDLFGVYATDVYTDEAIKVVNSHNKSEPLF 119 TG +D Y + + G G D G VA L G Y+T +Y A ++ SH+ PLF Sbjct: 171 LTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQRPLF 230 Query: 120 LMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRG 179 L +A AVH+ P+++P++ + ++ + + AR+K+AA+++ +DE+V + AL G Sbjct: 231 LYVAFQAVHT-----PLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYG 285 Query: 180 LLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKARVA 239 NS+++FS+DNGG + SN+PL+G K T WEGGVRG GF+ SPLL K R + Sbjct: 286 FYNNSVIIFSSDNGGQTF----SGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTS 341 Query: 240 YQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIWGIA 297 MHI+DW PTL AGG S + LDG + W A+S+ SPRT +LHNID ++ A Sbjct: 342 RALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHA 399 >BC129995-1|AAI29996.1| 569|Homo sapiens arylsulfatase family, member I protein. Length = 569 Score = 265 bits (650), Expect = 2e-70 Identities = 129/298 (43%), Positives = 185/298 (62%), Gaps = 10/298 (3%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I +P LPL++ LPQ L++ GY TH+VGKWHLG Y+KE LP RGFD+ +G Sbjct: 111 LQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGS 170 Query: 61 WTGRIDMYDHTTME-QGSWGTDFRRGFEVAHDLFGVYATDVYTDEAIKVVNSHNKSEPLF 119 TG +D Y + + G G D G VA L G Y+T +Y A ++ SH+ PLF Sbjct: 171 LTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQRPLF 230 Query: 120 LMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRG 179 L +A AVH+ P+++P++ + ++ + + AR+K+AA+++ +DE+V + AL G Sbjct: 231 LYVAFQAVHT-----PLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYG 285 Query: 180 LLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKARVA 239 NS+++FS+DNGG + SN+PL+G K T WEGGVRG GF+ SPLL K R + Sbjct: 286 FYNNSVIIFSSDNGGQTF----SGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTS 341 Query: 240 YQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIWGIA 297 MHI+DW PTL AGG S + LDG + W A+S+ SPRT +LHNID ++ A Sbjct: 342 RALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHA 399 >AY875937-1|AAW66665.1| 569|Homo sapiens arylsulfatase I protein. Length = 569 Score = 265 bits (650), Expect = 2e-70 Identities = 129/298 (43%), Positives = 185/298 (62%), Gaps = 10/298 (3%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I +P LPL++ LPQ L++ GY TH+VGKWHLG Y+KE LP RGFD+ +G Sbjct: 111 LQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGS 170 Query: 61 WTGRIDMYDHTTME-QGSWGTDFRRGFEVAHDLFGVYATDVYTDEAIKVVNSHNKSEPLF 119 TG +D Y + + G G D G VA L G Y+T +Y A ++ SH+ PLF Sbjct: 171 LTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQRPLF 230 Query: 120 LMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRG 179 L +A AVH+ P+++P++ + ++ + + AR+K+AA+++ +DE+V + AL G Sbjct: 231 LYVAFQAVHT-----PLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYG 285 Query: 180 LLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKARVA 239 NS+++FS+DNGG + SN+PL+G K T WEGGVRG GF+ SPLL K R + Sbjct: 286 FYNNSVIIFSSDNGGQTF----SGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTS 341 Query: 240 YQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIWGIA 297 MHI+DW PTL AGG S + LDG + W A+S+ SPRT +LHNID ++ A Sbjct: 342 RALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHA 399 >M32373-1|AAA51779.1| 533|Homo sapiens ARSB protein. Length = 533 Score = 260 bits (638), Expect = 5e-69 Identities = 128/297 (43%), Positives = 182/297 (61%), Gaps = 15/297 (5%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I+ +P +PL+EK+LPQ LK+ GY TH+VGKWHLG Y+KE LP RGFD++ G+ Sbjct: 109 LQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGY 168 Query: 61 WTGRIDMYDHT------TMEQGSWGTDFRRGFEVAHDLFGVYATDVYTDEAIKVVNSHNK 114 G D Y H + DFR G EVA +Y+T+++T AI ++ +H Sbjct: 169 LLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPP 228 Query: 115 SEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKA 174 +PLFL LA +VH EP++ P++ + + +I D R +A ++S +DE+VG V A Sbjct: 229 EKPLFLYLALQSVH-----EPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAA 283 Query: 175 LHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDS 234 L + GL N++ +FSTDNGG +N+PL+G K +LWEGGVRG GF+ SPLL Sbjct: 284 LKSSGLWNNTVFIFSTDNGGQTLA----GGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQ 339 Query: 235 KARVAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNID 291 K + +HISDWLPTL A G + + LDG + W +S+ + SPR +LHNID Sbjct: 340 KGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDMWKTISEGSPSPRIELLHNID 396 >X72735-1|CAA51272.1| 533|Homo sapiens arylsulfatase protein. Length = 533 Score = 260 bits (636), Expect = 1e-68 Identities = 128/297 (43%), Positives = 182/297 (61%), Gaps = 15/297 (5%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I+ +P +PL+EK+LPQ LK+ GY TH+VGKWHLG Y+KE LP RGFD++ G+ Sbjct: 109 LQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGY 168 Query: 61 WTGRIDMYDHT------TMEQGSWGTDFRRGFEVAHDLFGVYATDVYTDEAIKVVNSHNK 114 G D Y H + DFR G EVA +Y+T+++T AI ++ +H Sbjct: 169 LLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPP 228 Query: 115 SEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKA 174 +PLFL LA +VH EP++ P++ + + +I D R +A ++S +DE+VG V A Sbjct: 229 EKPLFLYLALQSVH-----EPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAA 283 Query: 175 LHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDS 234 L + GL N++ +FSTDNGG +N+PL+G K +LWEGGVRG GF+ SPLL Sbjct: 284 LKSSGLWNNTVFIFSTDNGGQTLA----GGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQ 339 Query: 235 KARVAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNID 291 K + +HISDWLPTL A G + + LDG + W +S+ + SPR +LHNID Sbjct: 340 KGVKNRELIHISDWLPTLMKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNID 396 >J05225-1|AAA51784.1| 533|Homo sapiens ARSB protein. Length = 533 Score = 260 bits (636), Expect = 1e-68 Identities = 128/297 (43%), Positives = 182/297 (61%), Gaps = 15/297 (5%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I+ +P +PL+EK+LPQ LK+ GY TH+VGKWHLG Y+KE LP RGFD++ G+ Sbjct: 109 LQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGY 168 Query: 61 WTGRIDMYDHT------TMEQGSWGTDFRRGFEVAHDLFGVYATDVYTDEAIKVVNSHNK 114 G D Y H + DFR G EVA +Y+T+++T AI ++ +H Sbjct: 169 LLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPP 228 Query: 115 SEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKA 174 +PLFL LA +VH EP++ P++ + + +I D R +A ++S +DE+VG V A Sbjct: 229 EKPLFLYLALQSVH-----EPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAA 283 Query: 175 LHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDS 234 L + GL N++ +FSTDNGG +N+PL+G K +LWEGGVRG GF+ SPLL Sbjct: 284 LKSSGLWNNTVFIFSTDNGGQTLA----GGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQ 339 Query: 235 KARVAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNID 291 K + +HISDWLPTL A G + + LDG + W +S+ + SPR +LHNID Sbjct: 340 KGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNID 396 >BC029051-1|AAH29051.1| 413|Homo sapiens arylsulfatase B protein. Length = 413 Score = 260 bits (636), Expect = 1e-68 Identities = 128/297 (43%), Positives = 182/297 (61%), Gaps = 15/297 (5%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I+ +P +PL+EK+LPQ LK+ GY TH+VGKWHLG Y+KE LP RGFD++ G+ Sbjct: 109 LQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGY 168 Query: 61 WTGRIDMYDHT------TMEQGSWGTDFRRGFEVAHDLFGVYATDVYTDEAIKVVNSHNK 114 G D Y H + DFR G EVA +Y+T+++T AI ++ +H Sbjct: 169 LLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPP 228 Query: 115 SEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKA 174 +PLFL LA +VH EP++ P++ + + +I D R +A ++S +DE+VG V A Sbjct: 229 EKPLFLYLALQSVH-----EPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAA 283 Query: 175 LHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDS 234 L + GL N++ +FSTDNGG +N+PL+G K +LWEGGVRG GF+ SPLL Sbjct: 284 LKSSGLWNNTVFIFSTDNGGQTLA----GGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQ 339 Query: 235 KARVAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNID 291 K + +HISDWLPTL A G + + LDG + W +S+ + SPR +LHNID Sbjct: 340 KGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNID 396 >BC132881-1|AAI32882.1| 599|Homo sapiens ARSJ protein protein. Length = 599 Score = 259 bits (635), Expect = 1e-68 Identities = 129/297 (43%), Positives = 183/297 (61%), Gaps = 13/297 (4%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I +P LPL+ LPQ LK++GY TH+VGKWHLG Y+KE +P RGFD+ G Sbjct: 140 LQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGS 199 Query: 61 WTGRIDMYDHTTMEQ-GSWGTDFRRGFEVAHDLF-GVYATDVYTDEAIKVVNSHNKSEPL 118 G D Y H + G G D A D G+Y+T +YT +++ SHN ++P+ Sbjct: 200 LLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPI 259 Query: 119 FLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTR 178 FL +A+ AVHS P++AP + + ++ I + R+++AA+LS LDE++ V AL T Sbjct: 260 FLYIAYQAVHS-----PLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTY 314 Query: 179 GLLENSIVVFSTDNGG-PAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKAR 237 G NSI+++S+DNGG P AG SN+PL+G K T WEGG+R GF+ SPLL +K Sbjct: 315 GFYNNSIIIYSSDNGGQPTAG-----GSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGT 369 Query: 238 VAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIW 294 V + +HI+DW PTL S A G + LDG + W+ +S+ SPR +LHNID I+ Sbjct: 370 VCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIY 426 >BC132879-1|AAI32880.1| 599|Homo sapiens ARSJ protein protein. Length = 599 Score = 259 bits (635), Expect = 1e-68 Identities = 129/297 (43%), Positives = 183/297 (61%), Gaps = 13/297 (4%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I +P LPL+ LPQ LK++GY TH+VGKWHLG Y+KE +P RGFD+ G Sbjct: 140 LQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGS 199 Query: 61 WTGRIDMYDHTTMEQ-GSWGTDFRRGFEVAHDLF-GVYATDVYTDEAIKVVNSHNKSEPL 118 G D Y H + G G D A D G+Y+T +YT +++ SHN ++P+ Sbjct: 200 LLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPI 259 Query: 119 FLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTR 178 FL +A+ AVHS P++AP + + ++ I + R+++AA+LS LDE++ V AL T Sbjct: 260 FLYIAYQAVHS-----PLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTY 314 Query: 179 GLLENSIVVFSTDNGG-PAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKAR 237 G NSI+++S+DNGG P AG SN+PL+G K T WEGG+R GF+ SPLL +K Sbjct: 315 GFYNNSIIIYSSDNGGQPTAG-----GSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGT 369 Query: 238 VAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIW 294 V + +HI+DW PTL S A G + LDG + W+ +S+ SPR +LHNID I+ Sbjct: 370 VCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIY 426 >BC089445-1|AAH89445.1| 578|Homo sapiens Unknown (protein for IMAGE:30706925) protein. Length = 578 Score = 259 bits (635), Expect = 1e-68 Identities = 129/297 (43%), Positives = 183/297 (61%), Gaps = 13/297 (4%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I +P LPL+ LPQ LK++GY TH+VGKWHLG Y+KE +P RGFD+ G Sbjct: 140 LQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGS 199 Query: 61 WTGRIDMYDHTTMEQ-GSWGTDFRRGFEVAHDLF-GVYATDVYTDEAIKVVNSHNKSEPL 118 G D Y H + G G D A D G+Y+T +YT +++ SHN ++P+ Sbjct: 200 LLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPI 259 Query: 119 FLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTR 178 FL +A+ AVHS P++AP + + ++ I + R+++AA+LS LDE++ V AL T Sbjct: 260 FLYIAYQAVHS-----PLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTY 314 Query: 179 GLLENSIVVFSTDNGG-PAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKAR 237 G NSI+++S+DNGG P AG SN+PL+G K T WEGG+R GF+ SPLL +K Sbjct: 315 GFYNNSIIIYSSDNGGQPTAG-----GSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGT 369 Query: 238 VAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIW 294 V + +HI+DW PTL S A G + LDG + W+ +S+ SPR +LHNID I+ Sbjct: 370 VCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIY 426 >AY875938-1|AAW66666.1| 599|Homo sapiens arylsulfatase J protein. Length = 599 Score = 259 bits (635), Expect = 1e-68 Identities = 129/297 (43%), Positives = 183/297 (61%), Gaps = 13/297 (4%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I +P LPL+ LPQ LK++GY TH+VGKWHLG Y+KE +P RGFD+ G Sbjct: 140 LQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGS 199 Query: 61 WTGRIDMYDHTTMEQ-GSWGTDFRRGFEVAHDLF-GVYATDVYTDEAIKVVNSHNKSEPL 118 G D Y H + G G D A D G+Y+T +YT +++ SHN ++P+ Sbjct: 200 LLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPI 259 Query: 119 FLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTR 178 FL +A+ AVHS P++AP + + ++ I + R+++AA+LS LDE++ V AL T Sbjct: 260 FLYIAYQAVHS-----PLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTY 314 Query: 179 GLLENSIVVFSTDNGG-PAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKAR 237 G NSI+++S+DNGG P AG SN+PL+G K T WEGG+R GF+ SPLL +K Sbjct: 315 GFYNNSIIIYSSDNGGQPTAG-----GSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGT 369 Query: 238 VAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIW 294 V + +HI+DW PTL S A G + LDG + W+ +S+ SPR +LHNID I+ Sbjct: 370 VCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIY 426 >AM049401-1|CAJ18095.1| 596|Homo sapiens arylsulfatase J protein. Length = 596 Score = 259 bits (635), Expect = 1e-68 Identities = 129/297 (43%), Positives = 183/297 (61%), Gaps = 13/297 (4%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I +P LPL+ LPQ LK++GY TH+VGKWHLG Y+KE +P RGFD+ G Sbjct: 140 LQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGS 199 Query: 61 WTGRIDMYDHTTMEQ-GSWGTDFRRGFEVAHDLF-GVYATDVYTDEAIKVVNSHNKSEPL 118 G D Y H + G G D A D G+Y+T +YT +++ SHN ++P+ Sbjct: 200 LLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPI 259 Query: 119 FLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTR 178 FL +A+ AVHS P++AP + + ++ I + R+++AA+LS LDE++ V AL T Sbjct: 260 FLYIAYQAVHS-----PLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTY 314 Query: 179 GLLENSIVVFSTDNGG-PAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKAR 237 G NSI+++S+DNGG P AG SN+PL+G K T WEGG+R GF+ SPLL +K Sbjct: 315 GFYNNSIIIYSSDNGGQPTAG-----GSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGT 369 Query: 238 VAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIW 294 V + +HI+DW PTL S A G + LDG + W+ +S+ SPR +LHNID I+ Sbjct: 370 VCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIY 426 >AY358647-1|AAQ89010.1| 515|Homo sapiens APRG372 protein. Length = 515 Score = 252 bits (618), Expect = 1e-66 Identities = 127/294 (43%), Positives = 179/294 (60%), Gaps = 13/294 (4%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF 60 +QH +I +P LPL+ LPQ LK++GY TH+VGKWHLG +KE +P RGFD+ G Sbjct: 140 LQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFNRKECMPTRRGFDTFFGS 199 Query: 61 WTGRIDMYDHTTMEQ-GSWGTDFRRGFEVAHDLF-GVYATDVYTDEAIKVVNSHNKSEPL 118 G D Y H + G G D A D G+Y+T +YT +++ SHN ++P+ Sbjct: 200 LLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPI 259 Query: 119 FLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTR 178 FL A+ AVHS P++AP + + ++ I + R+++AA+LS LDE++ V AL T Sbjct: 260 FLYTAYQAVHS-----PLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTY 314 Query: 179 GLLENSIVVFSTDNGG-PAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKAR 237 G NSI+++S+DNGG P AG SN+PL+G K T WEGG+R GF+ SPLL +K Sbjct: 315 GFYNNSIIIYSSDNGGQPTAG-----GSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGT 369 Query: 238 VAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNID 291 V + +HI+DW PTL S A G + LDG + W+ +S+ SPR +LHNID Sbjct: 370 VCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNID 423 >U06088-1|AAC51350.1| 522|Homo sapiens N-acetylgalactosamine 6-sulphatase protein. Length = 522 Score = 107 bits (257), Expect = 8e-23 Identities = 84/313 (26%), Positives = 140/313 (44%), Gaps = 22/313 (7%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGFWTGRIDMYDHTT 72 G+P +E++LP+ LK GY + +VGKWHLG ++ ++ PL GFD G YD+ Sbjct: 116 GIPDSEQLLPELLKKAGYVSKIVGKWHLG-HRPQFHPLKHGFDEWFGSPNCHFGPYDNKA 174 Query: 73 MEQ----GSWGTDFRRGFEVAHDLFGVYA--TDVYTDEAIKVVNSHNKSEPLFLMLAHSA 126 W R E +L A T +Y EA+ + + P FL A A Sbjct: 175 RPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDA 234 Query: 127 VHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIV 186 H+ P+ A + ++ S R ++ + ++D+S+GK+++ L + +N+ V Sbjct: 235 THA-----PVYASKP------FLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFV 283 Query: 187 VFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHIS 246 F++DNG + SN P K T +EGG+R W P + +V++Q I Sbjct: 284 FFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIM 343 Query: 247 DWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIWGIAALTVDKYKL 306 D T + AG +DG+N L + R + D + A T+ ++K Sbjct: 344 DLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDT---LMAATLGQHKA 400 Query: 307 IKGTIYKGVWDNW 319 T + W+N+ Sbjct: 401 HFWT-WTNSWENF 412 >D17629-1|BAA04535.1| 522|Homo sapiens N-acetylgalactosamine 6-sulfate sulfatase protein. Length = 522 Score = 107 bits (257), Expect = 8e-23 Identities = 84/313 (26%), Positives = 140/313 (44%), Gaps = 22/313 (7%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGFWTGRIDMYDHTT 72 G+P +E++LP+ LK GY + +VGKWHLG ++ ++ PL GFD G YD+ Sbjct: 116 GIPDSEQLLPELLKKAGYVSKIVGKWHLG-HRPQFHPLKHGFDEWFGSPNCHFGPYDNKA 174 Query: 73 MEQ----GSWGTDFRRGFEVAHDLFGVYA--TDVYTDEAIKVVNSHNKSEPLFLMLAHSA 126 W R E +L A T +Y EA+ + + P FL A A Sbjct: 175 RPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDA 234 Query: 127 VHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIV 186 H+ P+ A + ++ S R ++ + ++D+S+GK+++ L + +N+ V Sbjct: 235 THA-----PVYASKP------FLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFV 283 Query: 187 VFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHIS 246 F++DNG + SN P K T +EGG+R W P + +V++Q I Sbjct: 284 FFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIM 343 Query: 247 DWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIWGIAALTVDKYKL 306 D T + AG +DG+N L + R + D + A T+ ++K Sbjct: 344 DLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDT---LMAATLGQHKA 400 Query: 307 IKGTIYKGVWDNW 319 T + W+N+ Sbjct: 401 HFWT-WTNSWENF 412 >BC056151-1|AAH56151.1| 522|Homo sapiens galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysacchar protein. Length = 522 Score = 107 bits (257), Expect = 8e-23 Identities = 84/313 (26%), Positives = 140/313 (44%), Gaps = 22/313 (7%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGFWTGRIDMYDHTT 72 G+P +E++LP+ LK GY + +VGKWHLG ++ ++ PL GFD G YD+ Sbjct: 116 GIPDSEQLLPELLKKAGYVSKIVGKWHLG-HRPQFHPLKHGFDEWFGSPNCHFGPYDNKA 174 Query: 73 MEQ----GSWGTDFRRGFEVAHDLFGVYA--TDVYTDEAIKVVNSHNKSEPLFLMLAHSA 126 W R E +L A T +Y EA+ + + P FL A A Sbjct: 175 RPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDA 234 Query: 127 VHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIV 186 H+ P+ A + ++ S R ++ + ++D+S+GK+++ L + +N+ V Sbjct: 235 THA-----PVYASKP------FLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFV 283 Query: 187 VFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHIS 246 F++DNG + SN P K T +EGG+R W P + +V++Q I Sbjct: 284 FFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIM 343 Query: 247 DWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIWGIAALTVDKYKL 306 D T + AG +DG+N L + R + D + A T+ ++K Sbjct: 344 DLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDT---LMAATLGQHKA 400 Query: 307 IKGTIYKGVWDNW 319 T + W+N+ Sbjct: 401 HFWT-WTNSWENF 412 >BC050684-1|AAH50684.2| 522|Homo sapiens galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysacchar protein. Length = 522 Score = 107 bits (257), Expect = 8e-23 Identities = 84/313 (26%), Positives = 140/313 (44%), Gaps = 22/313 (7%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGFWTGRIDMYDHTT 72 G+P +E++LP+ LK GY + +VGKWHLG ++ ++ PL GFD G YD+ Sbjct: 116 GIPDSEQLLPELLKKAGYVSKIVGKWHLG-HRPQFHPLKHGFDEWFGSPNCHFGPYDNKA 174 Query: 73 MEQ----GSWGTDFRRGFEVAHDLFGVYA--TDVYTDEAIKVVNSHNKSEPLFLMLAHSA 126 W R E +L A T +Y EA+ + + P FL A A Sbjct: 175 RPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDA 234 Query: 127 VHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIV 186 H+ P+ A + ++ S R ++ + ++D+S+GK+++ L + +N+ V Sbjct: 235 THA-----PVYASKP------FLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFV 283 Query: 187 VFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHIS 246 F++DNG + SN P K T +EGG+R W P + +V++Q I Sbjct: 284 FFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIM 343 Query: 247 DWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIWGIAALTVDKYKL 306 D T + AG +DG+N L + R + D + A T+ ++K Sbjct: 344 DLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDT---LMAATLGQHKA 400 Query: 307 IKGTIYKGVWDNW 319 T + W+N+ Sbjct: 401 HFWT-WTNSWENF 412 >AK131096-1|BAC85146.1| 456|Homo sapiens FLJ00319 protein protein. Length = 456 Score = 107 bits (257), Expect = 8e-23 Identities = 84/313 (26%), Positives = 140/313 (44%), Gaps = 22/313 (7%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGFWTGRIDMYDHTT 72 G+P +E++LP+ LK GY + +VGKWHLG ++ ++ PL GFD G YD+ Sbjct: 50 GIPDSEQLLPELLKKAGYVSKIVGKWHLG-HRPQFHPLKHGFDEWFGSPNCHFGPYDNKA 108 Query: 73 MEQ----GSWGTDFRRGFEVAHDLFGVYA--TDVYTDEAIKVVNSHNKSEPLFLMLAHSA 126 W R E +L A T +Y EA+ + + P FL A A Sbjct: 109 RPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDA 168 Query: 127 VHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIV 186 H+ P+ A + ++ S R ++ + ++D+S+GK+++ L + +N+ V Sbjct: 169 THA-----PVYASKP------FLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFV 217 Query: 187 VFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHIS 246 F++DNG + SN P K T +EGG+R W P + +V++Q I Sbjct: 218 FFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIM 277 Query: 247 DWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIWGIAALTVDKYKL 306 D T + AG +DG+N L + R + D + A T+ ++K Sbjct: 278 DLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDT---LMAATLGQHKA 334 Query: 307 IKGTIYKGVWDNW 319 T + W+N+ Sbjct: 335 HFWT-WTNSWENF 346 >AY129021-1|AAM98764.1| 337|Homo sapiens unknown protein. Length = 337 Score = 72.5 bits (170), Expect = 3e-12 Identities = 55/222 (24%), Positives = 98/222 (44%), Gaps = 15/222 (6%) Query: 98 TDVYTDEAIKVVNSHNKSEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKF 157 T +Y EA+ + + P FL A A H+ P+ A + ++ S R ++ Sbjct: 21 TQIYLQEALDFIKRQARHHPFFLYWAVDATHA-----PVYASKP------FLGTSQRGRY 69 Query: 158 AAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLW 217 + ++D+S+GK+++ L + +N+ V F++DNG + SN P K T + Sbjct: 70 GDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTF 129 Query: 218 EGGVRGAGFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSK 277 EGG+R W P + +V++Q I D T + AG +DG+N L + Sbjct: 130 EGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQ 189 Query: 278 NTESPRTSVLHNIDDIWGIAALTVDKYKLIKGTIYKGVWDNW 319 R + D + A T+ ++K T + W+N+ Sbjct: 190 GRLMDRPIFYYRGDT---LMAATLGQHKAHFWT-WTNSWENF 227 >X52151-1|CAA36399.1| 507|Homo sapiens arylsulfatase A protein. Length = 507 Score = 66.1 bits (154), Expect = 2e-10 Identities = 51/161 (31%), Positives = 78/161 (48%), Gaps = 6/161 (3%) Query: 148 YIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNY 207 + + S R F L +LD +VG ++ A+ GLLE ++V+F+ DNG + S Sbjct: 238 FAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGL 297 Query: 208 PLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLD 267 L+ K T +EGGVR + P + V ++ D LPTL + AG L + LD Sbjct: 298 -LRCGKGTTYEGGVREPALAFWPGHIAPG-VTHELASSLDLLPTLAALAGAPLPNV-TLD 354 Query: 268 GVNQWDALSKNTESPRTSVL---HNIDDIWGIAALTVDKYK 305 G + L +SPR S+ D++ G+ A+ KYK Sbjct: 355 GFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYK 395 Score = 44.4 bits (100), Expect = 8e-04 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG-SYKKEYLPLNRGFDSHVG 59 M GV+ + GLPL E + + L GY T + GKWHLG + +LP ++GF +G Sbjct: 87 MYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLG 146 >X52150-1|CAA36398.1| 507|Homo sapiens arylsulphatase a protein. Length = 507 Score = 66.1 bits (154), Expect = 2e-10 Identities = 51/161 (31%), Positives = 78/161 (48%), Gaps = 6/161 (3%) Query: 148 YIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNY 207 + + S R F L +LD +VG ++ A+ GLLE ++V+F+ DNG + S Sbjct: 238 FAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGL 297 Query: 208 PLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLD 267 L+ K T +EGGVR + P + V ++ D LPTL + AG L + LD Sbjct: 298 -LRCGKGTTYEGGVREPALAFWPGHIAPG-VTHELASSLDLLPTLAALAGAPLPNV-TLD 354 Query: 268 GVNQWDALSKNTESPRTSVL---HNIDDIWGIAALTVDKYK 305 G + L +SPR S+ D++ G+ A+ KYK Sbjct: 355 GFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYK 395 Score = 44.4 bits (100), Expect = 8e-04 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG-SYKKEYLPLNRGFDSHVG 59 M GV+ + GLPL E + + L GY T + GKWHLG + +LP ++GF +G Sbjct: 87 MYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLG 146 >U62317-1|AAB03341.1| 509|Homo sapiens arylsulfatase A protein. Length = 509 Score = 66.1 bits (154), Expect = 2e-10 Identities = 51/161 (31%), Positives = 78/161 (48%), Gaps = 6/161 (3%) Query: 148 YIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNY 207 + + S R F L +LD +VG ++ A+ GLLE ++V+F+ DNG + S Sbjct: 240 FAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGL 299 Query: 208 PLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLD 267 L+ K T +EGGVR + P + V ++ D LPTL + AG L + LD Sbjct: 300 -LRCGKGTTYEGGVREPALAFWPGHIAPG-VTHELASSLDLLPTLAALAGAPLPNV-TLD 356 Query: 268 GVNQWDALSKNTESPRTSVL---HNIDDIWGIAALTVDKYK 305 G + L +SPR S+ D++ G+ A+ KYK Sbjct: 357 GFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYK 397 Score = 44.4 bits (100), Expect = 8e-04 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG-SYKKEYLPLNRGFDSHVG 59 M GV+ + GLPL E + + L GY T + GKWHLG + +LP ++GF +G Sbjct: 89 MYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLG 148 >CR456383-1|CAG30269.1| 509|Homo sapiens ARSA protein. Length = 509 Score = 66.1 bits (154), Expect = 2e-10 Identities = 51/161 (31%), Positives = 78/161 (48%), Gaps = 6/161 (3%) Query: 148 YIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNY 207 + + S R F L +LD +VG ++ A+ GLLE ++V+F+ DNG + S Sbjct: 240 FAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGL 299 Query: 208 PLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLD 267 L+ K T +EGGVR + P + V ++ D LPTL + AG L + LD Sbjct: 300 -LRCGKGTTYEGGVREPALAFWPGHIAPG-VTHELASSLDLLPTLAALAGAPLPNV-TLD 356 Query: 268 GVNQWDALSKNTESPRTSVL---HNIDDIWGIAALTVDKYK 305 G + L +SPR S+ D++ G+ A+ KYK Sbjct: 357 GFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYK 397 Score = 44.4 bits (100), Expect = 8e-04 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG-SYKKEYLPLNRGFDSHVG 59 M GV+ + GLPL E + + L GY T + GKWHLG + +LP ++GF +G Sbjct: 89 MYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLG 148 >AY271820-1|AAP03431.1| 507|Homo sapiens arylsulfatase A protein. Length = 507 Score = 66.1 bits (154), Expect = 2e-10 Identities = 51/161 (31%), Positives = 78/161 (48%), Gaps = 6/161 (3%) Query: 148 YIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNY 207 + + S R F L +LD +VG ++ A+ GLLE ++V+F+ DNG + S Sbjct: 238 FAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGL 297 Query: 208 PLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLD 267 L+ K T +EGGVR + P + V ++ D LPTL + AG L + LD Sbjct: 298 -LRCGKGTTYEGGVREPALAFWPGHIAPG-VTHELASSLDLLPTLAALAGAPLPNV-TLD 354 Query: 268 GVNQWDALSKNTESPRTSVL---HNIDDIWGIAALTVDKYK 305 G + L +SPR S+ D++ G+ A+ KYK Sbjct: 355 GFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYK 395 Score = 44.4 bits (100), Expect = 8e-04 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG-SYKKEYLPLNRGFDSHVG 59 M GV+ + GLPL E + + L GY T + GKWHLG + +LP ++GF +G Sbjct: 87 MYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLG 146 >BC014210-1|AAH14210.2| 507|Homo sapiens arylsulfatase A protein. Length = 507 Score = 65.3 bits (152), Expect = 4e-10 Identities = 51/161 (31%), Positives = 78/161 (48%), Gaps = 6/161 (3%) Query: 148 YIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNY 207 + + S R F L +LD +VG ++ A+ GLLE ++V+F+ DNG + S Sbjct: 238 FAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGL 297 Query: 208 PLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLD 267 L+ K T +EGGVR + P + V ++ D LPTL + AG L + LD Sbjct: 298 -LRCGKGTTYEGGVREPALAFWPGHIAPG-VTHELASSLDLLPTLAALAGAPLPNV-TLD 354 Query: 268 GVNQWDALSKNTESPRTSVL---HNIDDIWGIAALTVDKYK 305 G + L +SPR S+ D++ G+ A+ KYK Sbjct: 355 GFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRSGKYK 395 Score = 44.4 bits (100), Expect = 8e-04 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 1 MQHGVIYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG-SYKKEYLPLNRGFDSHVG 59 M GV+ + GLPL E + + L GY T + GKWHLG + +LP ++GF +G Sbjct: 87 MYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLG 146 >AY875940-1|AAW66668.1| 562|Homo sapiens arylsulfatase H protein. Length = 562 Score = 62.1 bits (144), Expect = 4e-09 Identities = 53/172 (30%), Positives = 81/172 (47%), Gaps = 18/172 (10%) Query: 104 EAIKVVNSHNKSEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVLSK 163 EA+ + + K EP L + VH+ P+ + +K + KY ++ + + Sbjct: 248 EALAFIERY-KREPFLLFFSFLHVHT-----PLISKKKFVGRSKY------GRYGDNVEE 295 Query: 164 LDESVGKVVKALHTRGLLENSIVVFSTDNGG---PAAGFNDNAASNYPLKGVKNT-LWEG 219 +D VGK++ AL L +++V F++DNGG P G N KG K WEG Sbjct: 296 MDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEG 355 Query: 220 GVRGAG-FLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLDGVN 270 G+R G F W +L++ RV + + D PTL GG LS +DG N Sbjct: 356 GIRVPGIFRWPSVLEA-GRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQN 406 Score = 45.2 bits (102), Expect = 5e-04 Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 6/72 (8%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLG---SYKKE--YLPLNRGFDSHVGFWTGRI-D 66 GLP NE + L+ GY+T L+GKWHLG + + + Y PLN GF G G + D Sbjct: 91 GLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRNDHCYHPLNHGFHYFYGVPFGLLSD 150 Query: 67 MYDHTTMEQGSW 78 T E W Sbjct: 151 CQASKTPELHRW 162 >BC012375-1|AAH12375.1| 525|Homo sapiens arylsulfatase G protein. Length = 525 Score = 59.7 bits (138), Expect = 2e-08 Identities = 78/304 (25%), Positives = 115/304 (37%), Gaps = 36/304 (11%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF----WTGRIDM- 67 GLPLNE L + L+ GY T ++GKWHLG + Y P RGFD + G G D Sbjct: 113 GLPLNETTLAEVLQQAGYVTGIIGKWHLG-HHGSYHPNFRGFDYYFGIPYSHDMGCTDTP 171 Query: 68 -YDHTTMEQGSWGTDFRRGFEVAHDLFGVYATDVY-----TDEAIKVVNSHNKSEPLFLM 121 Y+H G R + D + A +Y ++ + + + K Sbjct: 172 GYNHPPCPACPQGDGPSRNLQ--RDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQ 229 Query: 122 LAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSA----RQKFAAVLSKLDESVGKVV-KALH 176 A SG P+ A + A R + A L ++D VG++ K H Sbjct: 230 FIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDH 289 Query: 177 TRGLLENSIVVFSTDNG------------GPAAGFNDNAASNYPLKGVKNTLWEGGVRGA 224 T + EN+ + F+ DNG GP GF P K T WEGG R Sbjct: 290 T--VKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSP---AKQTTWEGGHRVP 344 Query: 225 GFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRT 284 + P + + + D PT+ + A L DGV+ + L ++ Sbjct: 345 ALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHR 404 Query: 285 SVLH 288 + H Sbjct: 405 VLFH 408 >AY358380-1|AAQ88746.1| 525|Homo sapiens GWLF839 protein. Length = 525 Score = 59.7 bits (138), Expect = 2e-08 Identities = 78/304 (25%), Positives = 115/304 (37%), Gaps = 36/304 (11%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF----WTGRIDM- 67 GLPLNE L + L+ GY T ++GKWHLG + Y P RGFD + G G D Sbjct: 113 GLPLNETTLAEVLQQAGYVTGIIGKWHLG-HHGSYHPNFRGFDYYFGIPYSHDMGCTDTP 171 Query: 68 -YDHTTMEQGSWGTDFRRGFEVAHDLFGVYATDVY-----TDEAIKVVNSHNKSEPLFLM 121 Y+H G R + D + A +Y ++ + + + K Sbjct: 172 GYNHPPCPACPQGDGPSRNLQ--RDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQ 229 Query: 122 LAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSA----RQKFAAVLSKLDESVGKVV-KALH 176 A SG P+ A + A R + A L ++D VG++ K H Sbjct: 230 FIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDH 289 Query: 177 TRGLLENSIVVFSTDNG------------GPAAGFNDNAASNYPLKGVKNTLWEGGVRGA 224 T + EN+ + F+ DNG GP GF P K T WEGG R Sbjct: 290 T--VKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSP---AKQTTWEGGHRVP 344 Query: 225 GFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRT 284 + P + + + D PT+ + A L DGV+ + L ++ Sbjct: 345 ALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHR 404 Query: 285 SVLH 288 + H Sbjct: 405 VLFH 408 >AB023218-1|BAA76845.2| 551|Homo sapiens KIAA1001 protein protein. Length = 551 Score = 59.7 bits (138), Expect = 2e-08 Identities = 78/304 (25%), Positives = 115/304 (37%), Gaps = 36/304 (11%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGF----WTGRIDM- 67 GLPLNE L + L+ GY T ++GKWHLG + Y P RGFD + G G D Sbjct: 139 GLPLNETTLAEVLQQAGYVTGIIGKWHLG-HHGSYHPNFRGFDYYFGIPYSHDMGCTDTP 197 Query: 68 -YDHTTMEQGSWGTDFRRGFEVAHDLFGVYATDVY-----TDEAIKVVNSHNKSEPLFLM 121 Y+H G R + D + A +Y ++ + + + K Sbjct: 198 GYNHPPCPACPQGDGPSRNLQ--RDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQ 255 Query: 122 LAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSA----RQKFAAVLSKLDESVGKVV-KALH 176 A SG P+ A + A R + A L ++D VG++ K H Sbjct: 256 FIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDH 315 Query: 177 TRGLLENSIVVFSTDNG------------GPAAGFNDNAASNYPLKGVKNTLWEGGVRGA 224 T + EN+ + F+ DNG GP GF P K T WEGG R Sbjct: 316 T--VKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSP---AKQTTWEGGHRVP 370 Query: 225 GFLWSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRT 284 + P + + + D PT+ + A L DGV+ + L ++ Sbjct: 371 ALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHR 430 Query: 285 SVLH 288 + H Sbjct: 431 VLFH 434 >X97868-1|CAA66462.1| 591|Homo sapiens arylsulphatase protein. Length = 591 Score = 57.6 bits (133), Expect = 8e-08 Identities = 56/206 (27%), Positives = 85/206 (41%), Gaps = 17/206 (8%) Query: 78 WGTDFRRGFEVAHD-LFGVYATDVYTDEAIKVVNSHNKSEPLFLMLAHSAVHSGNPYEPI 136 W RG E+ + A + EAI + H+K E L + VH+ Sbjct: 244 WDCLLMRGHEITEQPMKAERAGSIMVKEAISFLERHSK-ETFLLFFSFLHVHT------- 295 Query: 137 RAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPA 196 P D F S + + ++D VGK++ A+ GL N++V F++D+GG Sbjct: 296 --PLPTTDDFT--GTSKHGLYGDNVEEMDSMVGKILDAIDDFGLRNNTLVYFTSDHGGHL 351 Query: 197 AGFNDNAAS---NYPLKGVKNTL-WEGGVRGAGFLWSPLLDSKARVAYQKMHISDWLPTL 252 +A N KG K WEGG+R G + P R+ + + D LPT+ Sbjct: 352 EARRGHAQLGGWNGIYKGGKGMGGWEGGIRVPGIVRWPGKVPAGRLIKEPTSLMDILPTV 411 Query: 253 YSAAGGDLSVLENLDGVNQWDALSKN 278 S +GG L +DG + L N Sbjct: 412 ASVSGGSLPQDRVIDGRDLMPLLQGN 437 Score = 48.0 bits (109), Expect = 7e-05 Identities = 27/56 (48%), Positives = 31/56 (55%), Gaps = 5/56 (8%) Query: 9 AEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG----SYKKE-YLPLNRGFDSHVG 59 A P GLPLNE L LK GY T L+GKWH G S + + P N GFD + G Sbjct: 110 AVPAGLPLNETTLAALLKKQGYSTGLIGKWHQGLNCDSRSDQCHHPYNYGFDYYYG 165 >BC022389-1|AAH22389.1| 590|Homo sapiens ARSF protein protein. Length = 590 Score = 57.6 bits (133), Expect = 8e-08 Identities = 56/206 (27%), Positives = 85/206 (41%), Gaps = 17/206 (8%) Query: 78 WGTDFRRGFEVAHD-LFGVYATDVYTDEAIKVVNSHNKSEPLFLMLAHSAVHSGNPYEPI 136 W RG E+ + A + EAI + H+K E L + VH+ Sbjct: 243 WDCLLMRGHEITEQPMKAERAGSIMVKEAISFLERHSK-ETFLLFFSFLHVHT------- 294 Query: 137 RAPQKLIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPA 196 P D F S + + ++D VGK++ A+ GL N++V F++D+GG Sbjct: 295 --PLPTTDDFT--GTSKHGLYGDNVEEMDSMVGKILDAIDDFGLRNNTLVYFTSDHGGHL 350 Query: 197 AGFNDNAAS---NYPLKGVKNTL-WEGGVRGAGFLWSPLLDSKARVAYQKMHISDWLPTL 252 +A N KG K WEGG+R G + P R+ + + D LPT+ Sbjct: 351 EARRGHAQLGGWNGIYKGGKGMGGWEGGIRVPGIVRWPGKVPAGRLIKEPTSLMDILPTV 410 Query: 253 YSAAGGDLSVLENLDGVNQWDALSKN 278 S +GG L +DG + L N Sbjct: 411 ASVSGGSLPQDRVIDGRDLMPLLQGN 436 Score = 48.0 bits (109), Expect = 7e-05 Identities = 27/56 (48%), Positives = 31/56 (55%), Gaps = 5/56 (8%) Query: 9 AEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG----SYKKE-YLPLNRGFDSHVG 59 A P GLPLNE L LK GY T L+GKWH G S + + P N GFD + G Sbjct: 109 AVPAGLPLNETTLAALLKKQGYSTGLIGKWHQGLNCDSRSDQCHHPYNYGFDYYYG 164 >X83573-1|CAA58556.1| 589|Homo sapiens ARSE protein. Length = 589 Score = 51.6 bits (118), Expect = 6e-06 Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 6/132 (4%) Query: 142 LIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAA---G 198 LI ++ S + + ++D VG+++ L GL ++++ F++D+GG G Sbjct: 304 LITMENFLGKSLHGLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLG 363 Query: 199 FNDNAASNYPLKGVKNTL-WEGGVRGAG-FLWSPLLDSKARVAYQKMHISDWLPTLYSAA 256 N KG K WEGG+R G F W +L + RV + + D PT+ A Sbjct: 364 NTQYGGWNGIYKGGKGMGGWEGGIRVPGIFRWPGVLPA-GRVIGEPTSLMDVFPTVVRLA 422 Query: 257 GGDLSVLENLDG 268 GG++ +DG Sbjct: 423 GGEVPQDRVIDG 434 Score = 43.6 bits (98), Expect = 0.001 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 5/52 (9%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKE-----YLPLNRGFDSHVG 59 GLP NE + LK+ GY T L+GKWHLG + + PL+ GF+ G Sbjct: 121 GLPTNETTFAKILKEKGYATGLIGKWHLGLNCESASDHCHHPLHHGFEHFYG 172 >BC130438-1|AAI30439.1| 589|Homo sapiens arylsulfatase E (chondrodysplasia punctata 1) protein. Length = 589 Score = 51.6 bits (118), Expect = 6e-06 Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 6/132 (4%) Query: 142 LIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAA---G 198 LI ++ S + + ++D VG+++ L GL ++++ F++D+GG G Sbjct: 304 LITMENFLGKSLHGLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLG 363 Query: 199 FNDNAASNYPLKGVKNTL-WEGGVRGAG-FLWSPLLDSKARVAYQKMHISDWLPTLYSAA 256 N KG K WEGG+R G F W +L + RV + + D PT+ A Sbjct: 364 NTQYGGWNGIYKGGKGMGGWEGGIRVPGIFRWPGVLPA-GRVIGEPTSLMDVFPTVVRLA 422 Query: 257 GGDLSVLENLDG 268 GG++ +DG Sbjct: 423 GGEVPQDRVIDG 434 Score = 45.2 bits (102), Expect = 5e-04 Identities = 23/52 (44%), Positives = 29/52 (55%), Gaps = 5/52 (9%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKE-----YLPLNRGFDSHVG 59 GLP NE + LK+ GY T L+GKWHLG + + PL+ GFD G Sbjct: 121 GLPTNETTFAKILKEKGYATGLIGKWHLGLNCESASDHCHHPLHHGFDHFYG 172 >AK223199-1|BAD96919.1| 589|Homo sapiens arylsulfatase E precursor variant protein. Length = 589 Score = 51.6 bits (118), Expect = 6e-06 Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 6/132 (4%) Query: 142 LIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAA---G 198 LI ++ S + + ++D VG+++ L GL ++++ F++D+GG G Sbjct: 304 LITMENFLGKSLHGLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLG 363 Query: 199 FNDNAASNYPLKGVKNTL-WEGGVRGAG-FLWSPLLDSKARVAYQKMHISDWLPTLYSAA 256 N KG K WEGG+R G F W +L + RV + + D PT+ A Sbjct: 364 NTQYGGWNGIYKGGKGMGGWEGGIRVPGIFRWPGVLPA-GRVIGEPTSLMDVFPTVVRLA 422 Query: 257 GGDLSVLENLDG 268 GG++ +DG Sbjct: 423 GGEVPQDRVIDG 434 Score = 45.2 bits (102), Expect = 5e-04 Identities = 23/52 (44%), Positives = 29/52 (55%), Gaps = 5/52 (9%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKE-----YLPLNRGFDSHVG 59 GLP NE + LK+ GY T L+GKWHLG + + PL+ GFD G Sbjct: 121 GLPTNETTFAKILKEKGYATGLIGKWHLGLNCESASDHCHHPLHHGFDHFYG 172 >X83572-1|CAA58555.1| 593|Homo sapiens ARSD protein. Length = 593 Score = 50.4 bits (115), Expect = 1e-05 Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 6/132 (4%) Query: 142 LIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAA---G 198 L+ ++ S + + ++D +GKV+ A+ GL ++ F++D+GG G Sbjct: 307 LVTTSAFLGKSQHGLYGDNVEEMDWLIGKVLNAIEDNGLKNSTFTYFTSDHGGHLEARDG 366 Query: 199 FNDNAASNYPLKGVKNTL-WEGGVRGAG-FLWSPLLDSKARVAYQKMHISDWLPTLYSAA 256 + N KG K WEGG+R G F W +L + RV + + D PT+ Sbjct: 367 HSQLGGWNGIYKGGKGMGGWEGGIRVPGIFHWPGVLPA-GRVIGEPTSLMDVFPTVVQLV 425 Query: 257 GGDLSVLENLDG 268 GG++ +DG Sbjct: 426 GGEVPQDRVIDG 437 Score = 41.1 bits (92), Expect = 0.008 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 5/58 (8%) Query: 7 YGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG---SYKKEYL--PLNRGFDSHVG 59 + A GLP NE + L+ GY T L+GKWH G + + ++ PLN GFD G Sbjct: 118 WNAGSGGLPENETTFARILQQHGYATGLIGKWHQGVNCASRGDHCHHPLNHGFDYFYG 175 >BC020229-1|AAH20229.1| 593|Homo sapiens ARSD protein protein. Length = 593 Score = 50.4 bits (115), Expect = 1e-05 Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 6/132 (4%) Query: 142 LIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAA---G 198 L+ ++ S + + ++D +GKV+ A+ GL ++ F++D+GG G Sbjct: 307 LVTTSAFLGKSQHGLYGDNVEEMDWLIGKVLNAIEDNGLKNSTFTYFTSDHGGHLEARDG 366 Query: 199 FNDNAASNYPLKGVKNTL-WEGGVRGAG-FLWSPLLDSKARVAYQKMHISDWLPTLYSAA 256 + N KG K WEGG+R G F W +L + RV + + D PT+ Sbjct: 367 HSQLGGWNGIYKGGKGMGGWEGGIRVPGIFHWPGVLPA-GRVIGEPTSLMDVFPTVVQLV 425 Query: 257 GGDLSVLENLDG 268 GG++ +DG Sbjct: 426 GGEVPQDRVIDG 437 Score = 41.1 bits (92), Expect = 0.008 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 5/58 (8%) Query: 7 YGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG---SYKKEYL--PLNRGFDSHVG 59 + A GLP NE + L+ GY T L+GKWH G + + ++ PLN GFD G Sbjct: 118 WNAGSGGLPENETTFARILQQHGYATGLIGKWHQGVNCASRGDHCHHPLNHGFDYFYG 175 >AK223183-1|BAD96903.1| 589|Homo sapiens arylsulfatase E precursor variant protein. Length = 589 Score = 49.2 bits (112), Expect = 3e-05 Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 6/132 (4%) Query: 142 LIDAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGP---AAG 198 LI ++ S + + ++D VG+++ L GL ++++ F++D+GG G Sbjct: 304 LITMENFLGKSLHGLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLG 363 Query: 199 FNDNAASNYPLKGVKNT-LWEGGVRGAG-FLWSPLLDSKARVAYQKMHISDWLPTLYSAA 256 N KG K WEGG+R G F W +L + RV + + D PT+ A Sbjct: 364 NTQYGGWNGIYKGGKGMGGWEGGIRVPGIFRWPGVLPA-GRVIGEPTSLMDVFPTVVRLA 422 Query: 257 GGDLSVLENLDG 268 G ++ +DG Sbjct: 423 GSEVPQDRVIDG 434 Score = 45.2 bits (102), Expect = 5e-04 Identities = 23/52 (44%), Positives = 29/52 (55%), Gaps = 5/52 (9%) Query: 13 GLPLNEKILPQYLKDLGYKTHLVGKWHLGSYKKE-----YLPLNRGFDSHVG 59 GLP NE + LK+ GY T L+GKWHLG + + PL+ GFD G Sbjct: 121 GLPTNETTFAKILKEKGYATGLIGKWHLGLNCESASDHCHHPLHHGFDHFYG 172 >M16505-1|AAA60596.1| 583|Homo sapiens STS protein. Length = 583 Score = 46.8 bits (106), Expect = 2e-04 Identities = 42/176 (23%), Positives = 75/176 (42%), Gaps = 18/176 (10%) Query: 98 TDVYTDEAIKVVNSHNKSEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKF 157 T T EA + + N P L+L++ VH+ L + + S + Sbjct: 261 TQRLTVEAAQFIQ-RNTETPFLLVLSYLHVHTA-----------LFSSKDFAGKSQHGVY 308 Query: 158 AAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFND----NAASNYPLKGVK 213 + ++D SVG+++ L L ++++ F++D G + + SN KG K Sbjct: 309 GDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGK 368 Query: 214 NTLWEGGVRGAGFL-WSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLDG 268 WEGG+R G L W ++ + ++ ++ D PT+ AG L +DG Sbjct: 369 ANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNM-DIFPTVAKLAGAPLPEDRIIDG 423 Score = 44.8 bits (101), Expect = 6e-04 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 5/59 (8%) Query: 6 IYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG---SYKKEYL--PLNRGFDSHVG 59 ++ A GLP +E + LKD GY T L+GKWHLG K ++ PL+ GF+ G Sbjct: 103 LFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYG 161 >J04964-1|AAA60597.1| 583|Homo sapiens STS protein. Length = 583 Score = 46.8 bits (106), Expect = 2e-04 Identities = 42/176 (23%), Positives = 75/176 (42%), Gaps = 18/176 (10%) Query: 98 TDVYTDEAIKVVNSHNKSEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKF 157 T T EA + + N P L+L++ VH+ L + + S + Sbjct: 261 TQRLTVEAAQFIQ-RNTETPFLLVLSYLHVHTA-----------LFSSKDFAGKSQHGVY 308 Query: 158 AAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFND----NAASNYPLKGVK 213 + ++D SVG+++ L L ++++ F++D G + + SN KG K Sbjct: 309 GDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGK 368 Query: 214 NTLWEGGVRGAGFL-WSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLDG 268 WEGG+R G L W ++ + ++ ++ D PT+ AG L +DG Sbjct: 369 ANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNM-DIFPTVAKLAGAPLPEDRIIDG 423 Score = 44.8 bits (101), Expect = 6e-04 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 5/59 (8%) Query: 6 IYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG---SYKKEYL--PLNRGFDSHVG 59 ++ A GLP +E + LKD GY T L+GKWHLG K ++ PL+ GF+ G Sbjct: 103 LFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYG 161 >BC075030-1|AAH75030.1| 583|Homo sapiens steroid sulfatase (microsomal), arylsulfatase C, isozyme S protein. Length = 583 Score = 46.8 bits (106), Expect = 2e-04 Identities = 42/176 (23%), Positives = 75/176 (42%), Gaps = 18/176 (10%) Query: 98 TDVYTDEAIKVVNSHNKSEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKF 157 T T EA + + N P L+L++ VH+ L + + S + Sbjct: 261 TQRLTVEAAQFIQ-RNTETPFLLVLSYLHVHTA-----------LFSSKDFAGKSQHGVY 308 Query: 158 AAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFND----NAASNYPLKGVK 213 + ++D SVG+++ L L ++++ F++D G + + SN KG K Sbjct: 309 GDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGK 368 Query: 214 NTLWEGGVRGAGFL-WSPLLDSKARVAYQKMHISDWLPTLYSAAGGDLSVLENLDG 268 WEGG+R G L W ++ + ++ ++ D PT+ AG L +DG Sbjct: 369 ANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNM-DIFPTVAKLAGAPLPEDRIIDG 423 Score = 44.8 bits (101), Expect = 6e-04 Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 5/59 (8%) Query: 6 IYGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG---SYKKEYL--PLNRGFDSHVG 59 ++ A GLP +E + LKD GY T L+GKWHLG K ++ PL+ GF+ G Sbjct: 103 LFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYG 161 >AF160499-1|AAF22253.1| 382|Homo sapiens arylsulfatase D beta protein. Length = 382 Score = 41.1 bits (92), Expect = 0.008 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 5/58 (8%) Query: 7 YGAEPRGLPLNEKILPQYLKDLGYKTHLVGKWHLG---SYKKEYL--PLNRGFDSHVG 59 + A GLP NE + L+ GY T L+GKWH G + + ++ PLN GFD G Sbjct: 118 WNAGSGGLPENETTFARILQQHGYATGLIGKWHQGVNCASRGDHCHHPLNHGFDYFYG 175 >BC007825-1|AAH07825.2| 238|Homo sapiens GALNS protein protein. Length = 238 Score = 40.7 bits (91), Expect = 0.010 Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 4/132 (3%) Query: 188 FSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLLDSKARVAYQKMHISD 247 F++DNG + SN P K T +EGG+R W P + +V++Q I D Sbjct: 1 FTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMD 60 Query: 248 WLPTLYSAAGGDLSVLENLDGVNQWDALSKNTESPRTSVLHNIDDIWGIAALTVDKYKLI 307 T + AG +DG+N L + R + D + A T+ ++K Sbjct: 61 LFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDT---LMAATLGQHKAH 117 Query: 308 KGTIYKGVWDNW 319 T + W+N+ Sbjct: 118 FWT-WTNSWENF 128 >AY101175-1|AAM76860.1| 871|Homo sapiens extracellular sulfatase SULF-1 protein. Length = 871 Score = 40.7 bits (91), Expect = 0.010 Identities = 62/267 (23%), Positives = 112/267 (41%), Gaps = 51/267 (19%) Query: 24 YLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGFWTGRIDMYDHTTMEQGSWGTDFR 83 YL + GY+T GK +L Y Y+P G+ +G Y++T G + Sbjct: 129 YLNNTGYRTAFFGK-YLNEYNGSYIP--PGWREWLGL-IKNSRFYNYTVCRN---GIKEK 181 Query: 84 RGFEVAHDLFGVYATDVYTDEAI---KVVNSHNKSEPLFLMLAHSAVHSGNPYEP----- 135 GF+ A D Y TD+ T+E+I K+ P+ ++++H+A H P Sbjct: 182 HGFDYAKD----YFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKL 237 Query: 136 -IRAPQKLIDAFKYIDDSAR--------------QKFAAVLSK--------LDESVGKVV 172 A Q + ++ Y + + +F +L + +D+SV ++ Sbjct: 238 YPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLY 297 Query: 173 KALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLL 232 L G LEN+ ++++ D+G F +KG K+ ++ +R F+ P + Sbjct: 298 NMLVETGELENTYIIYTADHGYHIGQFG-------LVKG-KSMPYDFDIRVPFFIRGPSV 349 Query: 233 DSKARVAYQKMHISDWLPTLYSAAGGD 259 + + V ++I D PT+ AG D Sbjct: 350 EPGSIVPQIVLNI-DLAPTILDIAGLD 375 >AF545571-1|AAO33315.1| 871|Homo sapiens sulfatase SULF1 precursor protein. Length = 871 Score = 40.7 bits (91), Expect = 0.010 Identities = 62/267 (23%), Positives = 112/267 (41%), Gaps = 51/267 (19%) Query: 24 YLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGFWTGRIDMYDHTTMEQGSWGTDFR 83 YL + GY+T GK +L Y Y+P G+ +G Y++T G + Sbjct: 129 YLNNTGYRTAFFGK-YLNEYNGSYIP--PGWREWLGL-IKNSRFYNYTVCRN---GIKEK 181 Query: 84 RGFEVAHDLFGVYATDVYTDEAI---KVVNSHNKSEPLFLMLAHSAVHSGNPYEP----- 135 GF+ A D Y TD+ T+E+I K+ P+ ++++H+A H P Sbjct: 182 HGFDYAKD----YFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKL 237 Query: 136 -IRAPQKLIDAFKYIDDSAR--------------QKFAAVLSK--------LDESVGKVV 172 A Q + ++ Y + + +F +L + +D+SV ++ Sbjct: 238 YPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLY 297 Query: 173 KALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLL 232 L G LEN+ ++++ D+G F +KG K+ ++ +R F+ P + Sbjct: 298 NMLVETGELENTYIIYTADHGYHIGQFG-------LVKG-KSMPYDFDIRVPFFIRGPSV 349 Query: 233 DSKARVAYQKMHISDWLPTLYSAAGGD 259 + + V ++I D PT+ AG D Sbjct: 350 EPGSIVPQIVLNI-DLAPTILDIAGLD 375 >AB029000-1|BAA83029.1| 818|Homo sapiens KIAA1077 protein protein. Length = 818 Score = 40.7 bits (91), Expect = 0.010 Identities = 62/267 (23%), Positives = 112/267 (41%), Gaps = 51/267 (19%) Query: 24 YLKDLGYKTHLVGKWHLGSYKKEYLPLNRGFDSHVGFWTGRIDMYDHTTMEQGSWGTDFR 83 YL + GY+T GK +L Y Y+P G+ +G Y++T G + Sbjct: 76 YLNNTGYRTAFFGK-YLNEYNGSYIP--PGWREWLGL-IKNSRFYNYTVCRN---GIKEK 128 Query: 84 RGFEVAHDLFGVYATDVYTDEAI---KVVNSHNKSEPLFLMLAHSAVHSGNPYEP----- 135 GF+ A D Y TD+ T+E+I K+ P+ ++++H+A H P Sbjct: 129 HGFDYAKD----YFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKL 184 Query: 136 -IRAPQKLIDAFKYIDDSAR--------------QKFAAVLSK--------LDESVGKVV 172 A Q + ++ Y + + +F +L + +D+SV ++ Sbjct: 185 YPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLY 244 Query: 173 KALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTLWEGGVRGAGFLWSPLL 232 L G LEN+ ++++ D+G F +KG K+ ++ +R F+ P + Sbjct: 245 NMLVETGELENTYIIYTADHGYHIGQFG-------LVKG-KSMPYDFDIRVPFFIRGPSV 296 Query: 233 DSKARVAYQKMHISDWLPTLYSAAGGD 259 + + V ++I D PT+ AG D Sbjct: 297 EPGSIVPQIVLNI-DLAPTILDIAGLD 322 >Z12173-1|CAA78164.1| 552|Homo sapiens N-acetylglucosamine-6-sulphatase protein. Length = 552 Score = 37.5 bits (83), Expect = 0.097 Identities = 20/69 (28%), Positives = 42/69 (60%), Gaps = 3/69 (4%) Query: 127 VHSGNPYEPIRAPQKLI--DAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENS 184 +H N + IR + + + +++D++ R+++ +LS +D+ V K+VK L G L N+ Sbjct: 261 IHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLS-VDDLVEKLVKRLEFTGELNNT 319 Query: 185 IVVFSTDNG 193 + +++DNG Sbjct: 320 YIFYTSDNG 328 >BX537363-1|CAD97608.1| 496|Homo sapiens hypothetical protein protein. Length = 496 Score = 37.5 bits (83), Expect = 0.097 Identities = 20/69 (28%), Positives = 42/69 (60%), Gaps = 3/69 (4%) Query: 127 VHSGNPYEPIRAPQKLI--DAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENS 184 +H N + IR + + + +++D++ R+++ +LS +D+ V K+VK L G L N+ Sbjct: 205 IHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLS-VDDLVEKLVKRLEFTGELNNT 263 Query: 185 IVVFSTDNG 193 + +++DNG Sbjct: 264 YIFYTSDNG 272 >BC012482-1|AAH12482.1| 552|Homo sapiens glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) protein. Length = 552 Score = 37.5 bits (83), Expect = 0.097 Identities = 20/69 (28%), Positives = 42/69 (60%), Gaps = 3/69 (4%) Query: 127 VHSGNPYEPIRAPQKLI--DAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENS 184 +H N + IR + + + +++D++ R+++ +LS +D+ V K+VK L G L N+ Sbjct: 261 IHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLS-VDDLVEKLVKRLEFTGELNNT 319 Query: 185 IVVFSTDNG 193 + +++DNG Sbjct: 320 YIFYTSDNG 328 >AK223484-1|BAD97204.1| 552|Homo sapiens glucosamine (N-acetyl)-6-sulfatase precursor variant protein. Length = 552 Score = 37.5 bits (83), Expect = 0.097 Identities = 20/69 (28%), Positives = 42/69 (60%), Gaps = 3/69 (4%) Query: 127 VHSGNPYEPIRAPQKLI--DAFKYIDDSARQKFAAVLSKLDESVGKVVKALHTRGLLENS 184 +H N + IR + + + +++D++ R+++ +LS +D+ V K+VK L G L N+ Sbjct: 261 IHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLS-VDDLVEKLVKRLEFTGELNNT 319 Query: 185 IVVFSTDNG 193 + +++DNG Sbjct: 320 YIFYTSDNG 328 >U60111-1|AAB17952.1| 502|Homo sapiens N-sulphoglucosamine sulphohydrolase protein. Length = 502 Score = 36.7 bits (81), Expect = 0.17 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 6/66 (9%) Query: 133 YEPIRAPQKLIDAFKYIDDSARQKFAA---VLSKLDESVGKVVKALHTRGLLENSIVVFS 189 Y+P+ L+ F +AR AA + ++D+ VG V++ L G+L +++V+F+ Sbjct: 215 YDPLDV---LVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFT 271 Query: 190 TDNGGP 195 +DNG P Sbjct: 272 SDNGIP 277 >U30894-1|AAA86530.1| 502|Homo sapiens N-sulphoglucosamine sulphohydrolase protein. Length = 502 Score = 36.7 bits (81), Expect = 0.17 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 6/66 (9%) Query: 133 YEPIRAPQKLIDAFKYIDDSARQKFAA---VLSKLDESVGKVVKALHTRGLLENSIVVFS 189 Y+P+ L+ F +AR AA + ++D+ VG V++ L G+L +++V+F+ Sbjct: 215 YDPLDV---LVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFT 271 Query: 190 TDNGGP 195 +DNG P Sbjct: 272 SDNGIP 277 >BC047318-1|AAH47318.1| 502|Homo sapiens N-sulfoglucosamine sulfohydrolase (sulfamidase) protein. Length = 502 Score = 36.7 bits (81), Expect = 0.17 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 6/66 (9%) Query: 133 YEPIRAPQKLIDAFKYIDDSARQKFAA---VLSKLDESVGKVVKALHTRGLLENSIVVFS 189 Y+P+ L+ F +AR AA + ++D+ VG V++ L G+L +++V+F+ Sbjct: 215 YDPLDV---LVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFT 271 Query: 190 TDNGGP 195 +DNG P Sbjct: 272 SDNGIP 277 >BC130329-1|AAI30330.1| 536|Homo sapiens arylsulfatase family, member K protein. Length = 536 Score = 35.5 bits (78), Expect = 0.39 Identities = 14/40 (35%), Positives = 28/40 (70%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 R + A+ ++ D +G+++ ALH LL+ +IV++S+D+G Sbjct: 276 RAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHG 315 >BC036047-1|AAH36047.1| 542|Homo sapiens ARSK protein protein. Length = 542 Score = 35.5 bits (78), Expect = 0.39 Identities = 14/40 (35%), Positives = 28/40 (70%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 R + A+ ++ D +G+++ ALH LL+ +IV++S+D+G Sbjct: 282 RAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHG 321 >AY875939-1|AAW66667.1| 536|Homo sapiens arylsulfatase K protein. Length = 536 Score = 35.5 bits (78), Expect = 0.39 Identities = 14/40 (35%), Positives = 28/40 (70%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 R + A+ ++ D +G+++ ALH LL+ +IV++S+D+G Sbjct: 276 RAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHG 315 >AY358596-1|AAQ88959.1| 536|Homo sapiens Bone Rel Sulphatase protein. Length = 536 Score = 35.5 bits (78), Expect = 0.39 Identities = 14/40 (35%), Positives = 28/40 (70%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 R + A+ ++ D +G+++ ALH LL+ +IV++S+D+G Sbjct: 276 RAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHG 315 >AL832711-1|CAD38634.1| 483|Homo sapiens hypothetical protein protein. Length = 483 Score = 35.5 bits (78), Expect = 0.39 Identities = 14/40 (35%), Positives = 28/40 (70%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 R + A+ ++ D +G+++ ALH LL+ +IV++S+D+G Sbjct: 223 RAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHG 262 >AK222890-1|BAD96610.1| 502|Homo sapiens N-sulfoglucosamine sulfohydrolase (sulfamidase) variant protein. Length = 502 Score = 34.3 bits (75), Expect = 0.90 Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 6/66 (9%) Query: 133 YEPIRAPQKLIDAFKYIDDSARQKFAA---VLSKLDESVGKVVKALHTRGLLENSIVVFS 189 Y+P+ L+ F +AR AA + ++D+ VG V++ L G+L +++V+ + Sbjct: 215 YDPLDV---LVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVILT 271 Query: 190 TDNGGP 195 +DNG P Sbjct: 272 SDNGIP 277 >M58342-1|AAA63197.1| 550|Homo sapiens iduronate 2-sulfatase protein. Length = 550 Score = 33.9 bits (74), Expect = 1.2 Identities = 15/40 (37%), Positives = 26/40 (65%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 RQ + A +S LD VG+++ AL L ++I+ F++D+G Sbjct: 297 RQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHG 336 >L40586-1|AAA92014.1| 343|Homo sapiens iduronate-2-sulphatase protein. Length = 343 Score = 33.9 bits (74), Expect = 1.2 Identities = 15/40 (37%), Positives = 26/40 (65%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 RQ + A +S LD VG+++ AL L ++I+ F++D+G Sbjct: 297 RQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHG 336 >L13329-1|AAA16877.1| 550|Homo sapiens iduronate-2-sulfatase protein. Length = 550 Score = 33.9 bits (74), Expect = 1.2 Identities = 15/40 (37%), Positives = 26/40 (65%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 RQ + A +S LD VG+++ AL L ++I+ F++D+G Sbjct: 297 RQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHG 336 >L04586-1|AAA59192.1| 398|Homo sapiens iduronate 2-sulfatase protein. Length = 398 Score = 33.9 bits (74), Expect = 1.2 Identities = 15/40 (37%), Positives = 26/40 (65%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 RQ + A +S LD VG+++ AL L ++I+ F++D+G Sbjct: 297 RQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHG 336 >BC018054-1|AAH18054.1| 453|Homo sapiens ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function) protein. Length = 453 Score = 33.9 bits (74), Expect = 1.2 Identities = 14/40 (35%), Positives = 26/40 (65%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 ++ + VL K+D+ +G +V+ L GL EN V+ ++D+G Sbjct: 200 KENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHG 239 >AL035701-3|CAB56567.1| 453|Homo sapiens ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function) protein. Length = 453 Score = 33.9 bits (74), Expect = 1.2 Identities = 14/40 (35%), Positives = 26/40 (65%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 ++ + VL K+D+ +G +V+ L GL EN V+ ++D+G Sbjct: 200 KENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHG 239 >AF011889-1|AAC77828.1| 550|Homo sapiens iduronate 2-sulfatase protein. Length = 550 Score = 33.9 bits (74), Expect = 1.2 Identities = 15/40 (37%), Positives = 26/40 (65%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 RQ + A +S LD VG+++ AL L ++I+ F++D+G Sbjct: 297 RQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHG 336 >AB020686-1|BAA74902.2| 461|Homo sapiens KIAA0879 protein protein. Length = 461 Score = 33.9 bits (74), Expect = 1.2 Identities = 14/40 (35%), Positives = 26/40 (65%) Query: 154 RQKFAAVLSKLDESVGKVVKALHTRGLLENSIVVFSTDNG 193 ++ + VL K+D+ +G +V+ L GL EN V+ ++D+G Sbjct: 208 KENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHG 247 >Y08110-1|CAA69325.1| 2214|Homo sapiens mosaic protein LR11 protein. Length = 2214 Score = 33.5 bits (73), Expect = 1.6 Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 10/115 (8%) Query: 102 TDEAIKVVNSHNKSEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVL 161 T+ +KV+ + + S H+ N + +R P+ L DA + + S ++ V+ Sbjct: 1610 TNTVLKVLKPDTTYQVKVQVQCLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPREAEGVI 1669 Query: 162 SKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTL 216 VG +HT GL+ IV +S G + AASN+ +KN L Sbjct: 1670 ------VGHWAPPIHTHGLIREYIVEYS--RSGSKMWASQRAASNF--TEIKNLL 1714 >U60975-1|AAC50891.2| 2214|Homo sapiens gp250 precursor protein. Length = 2214 Score = 33.5 bits (73), Expect = 1.6 Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 10/115 (8%) Query: 102 TDEAIKVVNSHNKSEPLFLMLAHSAVHSGNPYEPIRAPQKLIDAFKYIDDSARQKFAAVL 161 T+ +KV+ + + S H+ N + +R P+ L DA + + S ++ V+ Sbjct: 1610 TNTVLKVLKPDTTYQVKVQVQCLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPREAEGVI 1669 Query: 162 SKLDESVGKVVKALHTRGLLENSIVVFSTDNGGPAAGFNDNAASNYPLKGVKNTL 216 VG +HT GL+ IV +S G + AASN+ +KN L Sbjct: 1670 ------VGHWAPPIHTHGLIREYIVEYS--RSGSKMWASQRAASNF--TEIKNLL 1714 >Y10183-1|CAA71256.1| 582|Homo sapiens MEMD protein protein. Length = 582 Score = 32.3 bits (70), Expect = 3.6 Identities = 14/48 (29%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 319 WYGPSGREGAYNASLLYDSHAGRILDKLNLMPPKEKVMELRDEATVKC 366 +YGPSG++ ++ ++D + + ++PPK + E D T+KC Sbjct: 223 YYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKE-GDNITLKC 269 >L38608-1|AAB59499.1| 583|Homo sapiens alcam protein. Length = 583 Score = 32.3 bits (70), Expect = 3.6 Identities = 14/48 (29%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 319 WYGPSGREGAYNASLLYDSHAGRILDKLNLMPPKEKVMELRDEATVKC 366 +YGPSG++ ++ ++D + + ++PPK + E D T+KC Sbjct: 224 YYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKE-GDNITLKC 270 >DQ486140-1|ABF48406.1| 583|Homo sapiens activated leukocyte cell adhesion molecule variant 2 protein. Length = 583 Score = 32.3 bits (70), Expect = 3.6 Identities = 14/48 (29%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 319 WYGPSGREGAYNASLLYDSHAGRILDKLNLMPPKEKVMELRDEATVKC 366 +YGPSG++ ++ ++D + + ++PPK + E D T+KC Sbjct: 224 YYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKE-GDNITLKC 270 >DQ486139-1|ABF48405.1| 570|Homo sapiens activated leukocyte cell adhesion molecule variant 1 protein. Length = 570 Score = 32.3 bits (70), Expect = 3.6 Identities = 14/48 (29%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 319 WYGPSGREGAYNASLLYDSHAGRILDKLNLMPPKEKVMELRDEATVKC 366 +YGPSG++ ++ ++D + + ++PPK + E D T+KC Sbjct: 224 YYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKE-GDNITLKC 270 Database: human Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 73,234,838 Number of sequences in database: 224,733 Lambda K H 0.317 0.136 0.425 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 70,514,316 Number of Sequences: 224733 Number of extensions: 2988268 Number of successful extensions: 4679 Number of sequences better than 10.0: 72 Number of HSP's better than 10.0 without gapping: 63 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 4509 Number of HSP's gapped (non-prelim): 112 length of query: 455 length of database: 73,234,838 effective HSP length: 92 effective length of query: 363 effective length of database: 52,559,402 effective search space: 19079062926 effective search space used: 19079062926 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.6 bits) S2: 67 (31.1 bits)
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